view test-data/samples/sample4/sample4_2.fastq @ 52:0acc1975bbeb

"planemo upload"
author jpayne
date Thu, 05 Nov 2020 15:21:19 -0500
parents eefdd97a6749
children
line wrap: on
line source
@r1
GCATCTCCTGCGCGGTATCAGGACGCCCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGNCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTC
+
,!,58+.7=@5A0C8;%C%"'*"'H;%AH5/5;;-$E@D+2F#3=A'@$&&*F+)%)617<9E54E?>(5&GAA..E@(>8/@E0)!.A':.2.%:A4517*'?)*A-%8,6<8(:#+))22%CHF"0*5)6C&*7(!+8"?1?2A7.5;8@1D$.@F+E:'.+@#287>B?+F1"";#&GC<$441C@#6H4-@,1513<@)F(A#C5,<3G6C5H'A-%4E
@r2
AGNAGTGCTNGATACCGAGGCTGCNGTGTACAGCGGTCAGGAGGC
+
'#!"'''')!*#$+*))*%"!+&#'"%$#&&*#*!#&*$%*!)(&
@r3
NAGAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGA
+
$.C36E>#G61/F%=4G4"GH<4%E+"=9G"8$A%9;)0>:1;E0'CF.1+F%@(6=#8C#'4BA#4,A;BA9:GH;$/)?-*
@r4
GTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTGTAAGGAACGATGAACATGAA
+
-F#BA-?35F'*H22/D"!"1:586=??2(=#;92/6E$-,1A8GD43@,3E&*#D1-G;&1A3B:($F:3"*&5.54..23-G<)G:5<0'"'7EG@G+4D2!*.%+2+90*F
@r5
GATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCNAACAACATGCCGGAA
+
)840?8.,!$3.).-<@-D,9*C'?>05##%;1,&&:E::->$?396+--@C?1,
@r6
TTCCCCTTGATTGNCCAGCCTCGCATATCNGCCGANGGATACGCGACAGCAAGTTTTGGGTAGGCTGATT
+
-8,#<25+EGG5B7DE,G35F-@?0277=0(+,>;&%G.$+>HG))/@(567E26B'/%5!H-E0"*>F$
@r7
ACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCT
+
H146/;B2G0<".9@<@>'<-64E0732,!@'DF6&9$2HD$9,,9D=
@r8
TAATGGTGATGTCTTTTTCCGTCACCCAGCCNCCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCNGTCACCCTTTGAGGTGGTTTCC
+
;>C:9H/.G'#'C07.C9B,*B8/'@-E?(C6<<?#H)@#<+)=AED@4AC*%H@B=.0-9>(9!G);*703!?*)<FD?="#6C$F.#GC.!*9:)2D#?
@r9
GCTGGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTT
+
";*:3<<HGB(1ED)/1%H*>5"5*#H<)A14F*1"('8?E'<7483E-'/?-'!((595H**";6D6+#1EH*7@(22#/>B/1'F4<:/!
@r10
GTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTAACAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTAGATG
+
')+&#)(+(!!%$)%))!$)+%($(+!+!"!'"%*$'+#&'&&"%"(++($))##)(""%!""&$'(*(#"&'()'(#&'&#$&%(("(&$$*#&"+(#+(*$+$&%')"$*!!#''&'&(#"*(&**%&#&(+)#%&(
@r11
TTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGT
+
&;&B$*"C?7-B&-*-*#9HH-:!A!#4=G3(&D';F&@F".":,.(C-<2%E+&"*4:DE6G*H021&21/+/:8#"@A)<?))<@C(8A.C"2+:8H51">/,D0<0%10?,7&33:4DA#!(4G.
@r12
CCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGANGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTT
+
5(7'<.F!EAH"!9C@(6*-$E!/8%5H!*9/**A=6G#,!;G@<D0#8?;=:/E@;-B<4!+20@D3=$6H$,!>*"/)$>#G7%0-67>DC<!"%29H3"A"'370F?>,B!G"'4F3F:3E$,;8601!B">&:F5&2)(.-,C!:'H=9*C+>8:B4(4,$G2
@r13
ATTCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACGTGTTACTGGTCGATTTAAGT
+
?@++2/9<BG-/(>C;=HA49)#(@?89/H="60:"%>!*A.2AC6!?44?#F860<5&)3'H);9>C,3C2A&G2B+
@r14
AGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGC
+
D(H2.-6(@-D#B6#-H)#=#H=$?6D<?H1;50*F?"?>%=+A,">23#.:5#2HEG+1E'D2*
@r15
NGTCTTCCAAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATATAGCGATGAAACATACTGAACTCCGTGCAGCCGTACNGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTNCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAG
+
#8AED$(;<3,'.8A<)<;#BE(+1%@G84A39D0?!/&9#/!@/%F'H==!B.+8)!DC/!,.)G,7'D-G=7?2C#;=$?.#CE39$E3"&"519C9"B#'82A)00/@=8G7,F"5%.A(E**HB?8()(=&@"*B"B9-%.-BG0F)%/<;#H)4H'5,9>'92/=0B"8,6F*"4-C#DD51D5:AC+5=>(=>A)7A<6/+3<#E6%EGD7H?F413,8D(21"9B+5B1=/?!B:/@A-929>(3GG8
@r16
ACCTGATGCTTTTCGTGCGCGCATAANATACCTTCATACTGTGCCGGATGAAAGCGGTTCGCG
+
:@3H%1@+580A;D0(E7)!#$E5.(878)';&H-+:**$-)"B0G'C6G*+%7;-0%;8*1C
@r17
CNAGGNTTTGCTNTCACNTNGTGANGTTCTGNAGCNNTTATGACGCCGAGCCGTAATTTGTGCCACGCAACATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATNCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGG
+
%%*#%%(%(%#)'(%&#!&)*(*#!(&%$%*!&'$$%*!"+'$''()+*(!$%$$"("#'%''+!)#(!$("%($)$+*"$%$)!%*$%$*)!)#!"!(##%)("((#%**'&)**#($+'"'$$#++$%#$(")*%#&&%(%+$!&*)""*%)'"!%%%##'"*#($)+*#++#$"#"$+#)*&#&%#%$$(&!
@r18
GCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTT
+
HH67&;::70H$+&8E@GG@"<8.3/2>-21;5<#:&*30!+"$#.8,(H09?CAD,="C+$%$>('FEE='#0@4G.<H>(8A<%:3>
@r19
AGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTT
+
.DCCB#+-F;,;C6(5+AF.#83!!F,-D'A3/)-CDC3&(B4&=7"&$1A+%/,&(18+=*-BB&3?D88>+0?+=5$F5=?9%H*@D)(>HD!C=DG!.&.H)33C#
@r20
GGCNNTNNTCTNGAGANCCGNATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGT
+
(*('&!!!(**##)#''$%'%((()+"()$#$&&#$%&!"!""!#$(##++*%*(
@r21
GCAGAAACTCTTCCAGGNCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGCCTTCACGGACTTCGTTGCTTTCCCGTTTANCAATA
+
A?'"+7B3=,C<0?"C4'?,9%:H<C>:B+?G("+1F<$(D*:),?<1@747/=0(B,((6C5A#5C)=?9HFHEF@-CB$@F&*-7.5?H?:?8A%A"<:62'DF!8E.;GD7*;&<E
@r22
TTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGTAATGGAATGGAGAGCCATTCAACAGAGNTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGAGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGAT
+
+F?584+:+;@*>@'*F;C1F*%(2!B4:?4,$(&.6.*9;:28E45.%&2B2,&#HE'8;0C"G?,-AC'G##C+0'@0<AF#H;):=*!+/$G'<C9(;C9-DF5,H<@(0:2*C=E<H?3"<A*!7A8'1;>B72(2'A03@D)F:,#,,A!G%5%2178"7.<084-%3#A'(4)-/5*7%8D=*7A
@r23
CTCCGGTGGCAGGACGTCAGCNTATTTGCTCTGGCTAATGGAGCAAAAGCGACAGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCA
+
*F0-3<?E<B?!&0F$++;.00+'H?18*.)*0"F774."-G++:+(H94336)(A5>H=3853/0'9<!%/,@>'F)6:D:5-A=9H&!:@F&3'2GD3/<'/99
@r24
TTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGG
+
")4(7:1.32H,F;/4$=HA&$%32!/<GE''%B3E,1.=*'/&;8;:$#33)%A/1<=C1>@?D-:)*D<99#;9H!)<F
@r25
CAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTC
+
-B>738+F*>%3=2$E&0<2&$(-/=&B#0'G101#?E*2
@r26
TCGTATCACACACCCCAATGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGC
+
;=B3@2/,8)F6(8D5G=0+-8$8>!5'8E&$:"*03577H1&<738"@$':"
@r27
CGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGG
+
12&(BB6!+"2&C51G&F699-3'E*$>'17G;3>9=@>0%B?.$H*;76<FD!<.
@r28
GAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGA
+
4*#&9&.+!$F8&>G8FG.3.0E"!9G!$'5)&E5C+$;0?9%..:#"!7*A$2=B7:-+2@)EE6)/3A)%B:?9>B#C'B:)B
@r29
TTCGCANCTATGGCTGCNTTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGG
+
@,DH6=5.?-G8,?9A,*:?,D.;4B#D#<C0/58@6>.9G!!163+?@%HC6;.%#?E?@:!0#B8?H?EC7H5:-#'F
@r30
NCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCNCAGA
+
!=4?2'AA=/%858+*77GB8(F&*$D*=CE@;@G#>+=0/%'BA,6<*(
@r31
AGCGTCCGGAGTTCTGCCTGAAGCATCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTCGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAANCCTTCTGCGCCTCTTCGGTATNTTTCAGCCGTGA
+
F211>>3B$32.)BA,G#=:B4-95%$4;3D0'#(9)/G/HC:;;@*#E@3FG/=:&E%;!!974B=*,+5@C&A"=!?5#B!4E9>*&)&AC%8D:%7>H"-5&!9*&3%$C)0+B8).=)D>F):3*!#":4=1:-->'.$/=%B=341,'6>.(/B@@AD<"4)&A)!?2B=H>:7=H/"=-BBFB.4H7,,5@&2F(6H#?<0,><"#/<7*/C5631:G;&7-)G2+!0F@#41!='"*3$*4&D7(31!A&*@</(@*E=%8#5E;.4"C=6$
@r32
ATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCNGTCGACGCTTATAAAA
+
,%#;4H/>**D9)@F=1+9=+1F@48"F?&DH2B>A+<?@5>=E*AF*@A4*21/,6<##8.8+>0)<6H>,"HD!%68E:3
@r33
ATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGN
+
92!&+CB?(/229&83D8AD/,A*H;2&@<.=(?./'+<%,;848-(!<$D;@6?;(2'64@H'!D=&B-E+
@r34
NGCNTNATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGAT
+
"("#'!"%)+"(*$$&!+!((#+%))%&&**(()&)!)"&+$&#%%")"$&$'&&''"##''!'""))()(&+'%+")#(&(#))"
@r35
NCANCGACCGGACCTTCAATCGGCCCTTCGCTAATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTC
+
%#$&$&(+*!((%!%""()"$'*+"+")"")++%!&&'!()'#"(!+%'&!&(+$'!#%$#")('#&#$""'%%!)*#($(!#*#"'!$&!!+$&%&&()"")"&)$*($"#'*$&')%"%*"%!#*#*('#"
@r36
CAATGAAGGAAACACTTGATAAATGCAAAGAGANTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGT
+
AE6<)3!+G,;B*6!<(%1'%:80#026.0%$F0E>A;0(4=C6E83/:)./&@E>58)0C9EF@!05)/4'&8!E<6%;(6D$;4A0$&.A+;DH>2%?1$
@r37
GGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATC
+
6A'81F=29='FH?=#79&.7;68$G%H1E((DEF!8;AA2&6;A'F"&6G.)2--0E@;28+20,24G80%D7?"&1?7(E&@%*,2#=1C!;"4;.C/=2<5*9;/5+#-8!A<&88
@r38
TANCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCT
+
;0%)39CG.A;!2A'?A=D55!)!*81)5B(:H"A6!F/9:"1<&=#B"B)&#;4=#=42D4#>/+1+%G&:50BC2@8,F-33,7@;.)F*$;8?%?75-E>%D"F8+&C
@r39
TCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTG
+
9,8,!#CH6D$H=!&1#?*",%</9/5*:335#6A9,*?<6$?8-AE!3(B)6"(212&$C8@1*5@8%-9;F3:3CD&%57+4#'8;=EG9;-"?E',#1=
@r40
GAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAG
+
!72*2>,=9*!>&+3/4::,!5CE;(4<$=;=@$##H4!B=#(1FG5>'D-?*984/"))5)+1:@H99C19$,")=%E2.
@r41
AGGAATGGGTAAAGGAAGCAGTAAGGGCCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTGGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGCAGGTCCGGTGGATGGCTGAAAAAGCGTGCTGCTGAACAGTAC
+
B&H:<<B.0,+=!&B#$;>H(,9):<2$=$3G0#!:D39!'2A46?<*1>+FA)A%,A1/.F),+55FC01*F)B2!)6A/$;D+?*D=1H6F9!>8:@CA4D%"3/0&6;99G0-7(-H&0<<4/#..3<19FA7?%%C6<.F7FF40&H.!
@r42
NGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAAC
+
"4!+9?0:#@9%%-9+,"-#<C"3/02*D(8;,4%,#:!6E)8:)%8A-:B96$B@.3:<-+"9E"+:4G<H2""D#+5
@r43
GGTGCTTNTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCNCGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAA
+
9HG%(/-?7$F2?16%>9F1:#4">;.1E"/*@$$G%C)0(4#FE%;#A@=@@1C6(78/:B$)>4B%!$&E"@CGG6&/&93'(.5E*&=(F;4<A5@F.)&!>'<@G=;==-'!)>76"808A27)&C9G4F":9-5'$*G#H<%")C.?82-*
@r44
CTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTNCCCCATGCCGTAGNGCGGATGGGNCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTT
+
A*-B/H(%0CF#$1;/1D5$+#8H%5%9@"C'=2@D5:G-#=2HBD/B)?<)H(,19/%<551;E?=,62F@"24$=B$E;,*(37%-+-FE52//=G6F16*#F**A!&?(=?!'F-<#%G>=8
@r45
CGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTT
+
*0E+G(@929*+?6FD=*5;<036+!"=$#H$;3425=7A
@r46
CAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCG
+
C=<>>;-0<'1/7B+-C;8F>(&57<%+CA9>)<0,<;11GG$)H&#)>%>7;!!G3;=0455=6,7("2
@r47
CGAATCTTAGGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTNTTTCCGCTTTTTCGCGTNCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTNCAGACTCTGGAGAGCA
+
DFE4;CH!5$AD71(+=H1!$A("G!7:3(1B8G8A.E+@$AFAHA;&2!A<!(&41$-4920,+F95:@#@6!*9B(;,.2/:+-?2E+1>A)G:)!/;"EC,D6$">8*/*+F&:*/-B7(F5:>D
@r48
AACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGATAA
+
<F?&.C676!(>884*!H5@+'#?E9?;,"((8?F%-*CH6D%+*;&!
@r49
TTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTN
+
A7&>H?5BAE7A4!>19=!)8*089'A5)A+>AF:+2?4075<ABA%FB/!"5F$2'4>;&8,@
@r50
ATCGGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCTCTTCTT
+
*;"#5F.0BDE"08E+C*H)):51&6=0/8=C8($<7;4'2>#"D&F7(D131$"H,-F7/4?&(/,35!!.+DEA1%57
@r51
AAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGNGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGNAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTATGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTNGATGACATT
+
,6=,(9683D2$9:699=D!$2(%3*877AB?3EF/<=31-*506":@4,'@'61<+2+B#,04,%A%.74G>B&?&7"E6/A+/F7*+*!?<5&*>/2D7):*0C;4,!EAC64H*>!-.<B!&)=/:F9H"A*-<G;CB+2+%H:8#20":A8*C'5185F3.C8H.@:@61=C40.G$@)<4F';$G$.0E!
@r52
GTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGG
+
4%(,3+-&AH/"&H9F4D@=H>%)'HFF7D,H"4=40,)5?H9$%:E::<8E0+2.).<(!?G'H=(:-*:)#F?C'!F1#B&,6E$:G"/55,(F""):D%9!G)1(C87685
@r53
NAGATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGG
+
$(&+!)!%""+'+$(&('&""#'+'&(($(!##(""))()&+""(#$+&'(!*$%&$#!((#'&#&'&%#%+'''**&'#$#*($(#)(%'$#'"%'$''*)(!*!"*%)*#+*!)&)#!*"!!%#
@r54
TAATGANTTATCAAAGGTATAGTAATATCTTTTATGTTCATG
+
(16B<510;:!&'-E,A@,96/!*A;"G"<8>H5.8D5-HF3
@r55
ACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCCAAC
+
>GBG+27E6F;=(;*%,6H?;44AE30/>-32@%:/#/.6#F""@D3G.#;%B96%12+F@/@"=DD8":@?!@?*F-:8?(?='G:.@+:4$3,E,:1@4+6'#4+C&*7,-=<"8@A31:B>@B<*&!@@":1+9./6E(&#@B3!(.G:H845)+"A
@r56
CGNTGATTNNTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAANCTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGC
+
#)"'#$&'"+$"+$(!**(*$&''+*#(!%$)*'%('"$((&+("*)"#*"!%#"$!("$+#"'(%"#'!#)#%+$*"$!%"#'%$&)'"((+%"'!'!*)$#)
@r57
TTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCAATCGGCGTCATGATGGCTCACAG
+
1'95#>7?(F%7<EF?@%0=/7-H?C/7>".5$F144$C);)";H-6&4D&:2=7%.F")29+E6!*6,/9+,<,8
@r58
CCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCG
+
44?FB(60*+@!C1C-7;D:BD-8"&*(.>(9C74F&E/!561@5AH%5(1,%%#@D$8*E')064+&-><A:*&3H#2@$>#BFC1+A/C&&.'0H8'H44,B";"
@r59
TGCGTACCTTCGNGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGCTCATTCGTGACCTTCTCGACTNCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCT
+
"+&$&)!(++)"('&)&!'*##(#!'(+"(##)+"$"&!$$#$'*%#&'!"!)##$)*%*'+#$%$$+&*%!'%*#"*)!*+!%'#"*(*(!*"&!%%%+!++'&+$+*#""$$"%$$+*)+(&**")*#'+'*"!'#"#+*#'%$'((*#&&$*
@r60
CNGTGGCGAGCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCTTTTCCGGCAATCAGGCGGGA
+
/7&+3C0B-<1+%'&;5<8*/?#6#++56*4,>/>A8+#%/2,<,"9-4)8G/*!4B<3$3HH90:E-$-52-69,>6:E.F5(5(?3$(32<%&%-B
@r61
TAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAA
+
9%C?@E&H""45H4EAE$'-?.<.';'5).3@3<1CCB)*6!HB04@:%(>9?$B=HD3586%6C3#7!&:%(C9<B;?#33,)97=2=@()-BF/010+2,+.!F=),78C3D3G$&$2<."1@B@)7.HA2D)"%;8+7CC!"D-F67C8!)#G*2C>4$&7.B7D&*'35/2A40H&.-22?>!02HA)+-4%->E-8A$=&)?!+9<68.+#<C:F/F<$'<?;6'?)&52=%+&6C6H<,A1:<=G+D?0G893!G
@r62
CCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGC
+
"=*+D3!0<8#>*"7$A5DC8/A!=-F=$;09>4">2:H?&/G3/1C5+<>@+(6#@H@HE%!(D<!H+!+AF>?+B-)3+G'.2@5,@%562G1!;-%0$A@6-ED
@r63
GATTTCGAGTTGGGTCCNCTTATCGCGGAGTTTGGCCGGGCNCAGCACGTTACCGGACCAGA
+
+"!"#)$+*!%$%%#)!)&')$+()!($&(&)"%&''+#("))!$!)"+*$(!&!"!!!(%#
@r64
GGGTCCTAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATTGCCTCGAAACCACCGAGCCGGACCTTCATGAAATCCCTGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGATACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGANTTCAAA
+
.(C2.&9;*,H!G9.8"B84;$-H>-,10H98@'#0(72D+3!!"#&,H<*.%@>5?5(".ED30!GA#+B<F=&2;?;D&$='+:#@49F*&2G6?,$?#'(C*:"?%."E04>3,#/56/$(0+*0/!#7%#'6!F4<&7-.EF1*E)B$=</E68'80@/=85#)%B>9H.;*0*1365)=3*-CB93H@(GH7BEGA($9A5.>-25E-=%F#:8*;>(;57C-+CE91H5"<F:*D*H&:?45!<+0"5(&=
@r65
NNCTGACGGCGATGGCTCGGCAGTTCCATAACGTGTCGGCGGAGCAGATTG
+
##<44$:-805(C#-/40C(;%C1+$07%558?.5!>"-$?B>'->.-;H?
@r66
NNGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCNAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGA
+
'#2;(2,1C+>9:D/;$:A.?*D(4$>==">3DF%!45:G",4D308(,7/&;945'F#D1-7?$'!67H.?A".<E"H:"-B*<B376.<=!!&3(F42)/D4<!$51@%4?($<5#7G<@/E$49>42=A,148-=6)31$/<-7CE'6%27($E5?6;3G1,*:D!1#-A:0?(+FF99#9H"?2<5$HH;7;.H647-%H+1+EAB;E;@.0&2/=*<=/+00)(#':-D40C')
@r67
ATGTCGTGATTGAGCGGGANGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCNGAGTTCATCGAAAAAATGGACGAGGCACAGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATNCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTT
+
@-D8$'?:!E@(,2(B*)(:4BB)/&,B-95:507>E)B!EA"';1@<0(,?@>/F:/(0*8A:#)9=B3?6&FCF8D0-*1A0$!1<>%(."?:.*3=D#-0/-9EA/@04#'7?-*A;=.(6770+=$(<@93&=7@*$!>3(5=<2G1=43CG1.="(:C9H396*<$.27<?)713"0<33B6DC;"@=)60969
@r68
CANCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCAGAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAA
+
<%">A(?*"=AH,B74"*;H:E!B<%+"/'D0)&(+6(;F:B:@$$=(:&@%1<)*9;?0'/H8E:E4)6<#1::3;&"==//=7H/6(@CE5
@r69
CGNCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCNGACCG
+
&.>+)%->*0F$82>,H':F#,5.:&A==3%3A.3'G8EA"(FDH5<-):3=+=/6$;"G.C?17D:<%52;)F:&@%B(5'&1B11"*5,,8#+4;=1"#"<#%6C=*5E25$!!5)F@!?$*3:99C!#?G@
@r70
NGTGGNAGCCGCCCGAAAGAATGCTGAGCAGCAGACTCAACAGGA
+
!"&#)%+#'!)!*#!)((*"#!(*%'&$*)*$($%*!*)&$$%*)
@r71
AGGTTTNGGTANNCCAGATTGCGTATGTTGCACAGTTGCNGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGNCGAACGAGGCCGCANCGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTNGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGG
+
##'%")!)%!"&##++!*(#!%()+!%%"'#(&*%!$($(&&*&+"#!*$*"!+*"++*))%$+')#&!'(*!!$)#$'!#)+("$*)&!#'*"*)!)+&%"%&(*+(*#%!"!*%&&(%%!$)(+"'+%&!$''##(&!&%)$%"*!!)$&#"&$%!($$#$"'+)&#%*"#%'#"(+(#+%+#(*+%$%"#!*
@r72
CCGGATGTGTTCTGCCNTACGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCNGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGG
+
=<)%C,;1D,4)H7B%!+>.&C&$43%E%!!5/D*CAC@?&'!)3+B5D,C175B0#:3B?6,-<+#/H>D/14$*,,7<*,.,"$E-27"//>,@6*9>;7(5FH;(+8C<A-44478.,+'E-/-7,43>%'
@r73
GCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGNAA
+
"8("25;&5<=)*C#G??*2#H(7:$=B/;!?B/<%3@+/$?95,/399H%2G%#A
@r74
GGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAAT
+
,%G$"0()0)DH/85A&<!"'0A,8'A0=:?*H=#B<C$<$5;0G52
@r75
TNCNNTNATCAGAAGACCTGCCCGTGCCNTTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAA
+
##*"#&#""+!"$$#&&'()"++!%&((&%""#$&$%!&#+''!%##'%))*'(+(+!'&")*)#'*(*#%*)#$+*+'$(*!
@r76
NCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCA
+
!+7-6!&G)G04;!08+*@@0:;.4&3D+(*2.BCB59-&=@704!C'55+.85,:76*)C
@r77
NATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTNC
+
!$7#C=!+."FA-93D9,9FB"!*'3**;G4'$;0G&3)8!9#$0)/#.4!2,C?76?F#6D4-F7@,28)&0+;:,77*G1"5)0/;:02H886426:H/#4%C))7$E4H5D=F;H1"(FF@EB$A=)"7.#4
@r78
ATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACG
+
@+$/.D:''C?;9?(7<*'#H<3.02A1#%$:65?GH@/.:5%#
@r79
TGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACNGACGGCGTGAAGGTAAAAGTGAGACGTGTTCCTGACGGGG
+
2.'B"?5'5,DE,!<?825;.$%7%*97(9:?3B!%$==.A4GC*62EGAH/>%,#$8B>4&032%*9!@2&#&@8'3;<==D0>="#%>7:B
@r80
CCNNGCAGNAATNGNNTTACGCNATNANTNNNCGCNNNACNGANATNNNCNNNGATCNNAANCAGNT
+
"""#"#!"!$"$#$!#"!!$#$!""###$!$#$$$$!#"#"#!""#!"#!""!"""#"!$!#"#"""
@r81
TCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCAC
+
@#9E7E"2'5$(E!#>-;:?0>E&2!,%33("*!5AF5.8+"
@r82
CTGAACTGTCAGCCNTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGTGGGGTCAGACAGCAACC
+
5>@5B418('A&6:1.%'(F/!.*)=E.$D73>6&@'9%F)'?$)CHG)01%@G'.20E$.B%C2/H(:7<A=.F8H?G";
@r83
ATCGAAGGTANGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAANGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGG
+
>35:#7!#D(.@>D>%*D#0.AGH+-)86C''#?=4-(BA91;("2&,+/6-F&+4827*.F"&,31(3?/701(;4>$#HG/=4'7CB.G
@r84
GNAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGT
+
(!9$57=4$9'F&,$5-&<>(&62);F--36,(?,0?9@?E@=59A>:"0=:;#C/$,;*:93+&@BB61H1D+5%%.4'-5$962@?5D"6=+/>.'?%,:8*
@r85
TTACCTGCGACATACTGTCNGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATCCAGT
+
7GH:+'')6'0+:%H5G!!!G-*9>$73+.;2!4.,(#H4=F#'2722')'F/*<D(G-<==2;8<4H"<
@r86
NCAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGNCTTTACGAGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCNGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGNCGGGCGGGACG
+
!(?-),<)&(*-F35'CH#$5A59<)2?$C-/A:0B.D5-GB8D$>#+2/.)?F8$$+6"1G8G<5>4H-+A-/:/=#?)G#?F*>;!E%=:67;)@#G9;",C4C+$FD4<&40H)9+#-DGD1HF'?B*!8'D#@H1B@="G91!;-+1>E8B@%66:9B(;H'=;&EC+:$.#3:(1??G1-$G6'8=F88%%F3;?8,"1B$.;'
@r87
CCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTNCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCAGCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTAT
+
&G7EH/4/;/#5FG@*'<4*.=(,%<E6(HA*E/9%.-5%>#%G5BA=)<!HB0:A2"91!*,6=)6$))9<!!&@)%/..03C;?><9G5+8:7E5"+H5C2DH31G!;08!&:D,%8-)766:(!C=D7A5A:80(%G4:-?9B095H":E49-))>=D2F.;E<F@;-7//3HC#
@r88
TTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCG
+
&98B"E='CBF*G5)%;EA9@$6)G4"*53<H:?=$'1;)+%3+=;$C?9+#H%C
@r89
CGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATNACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATG
+
9?=;65B?E2*15HC9B8'3,17B"&#>-G(6(";>>!DB5!(2H>'H$-:303-4/4H,!@AE84G<7>,&B37;;)A"+8E8$'/:(&'2=B<,.A3<!!>-.((
@r90
TTCAATCTGTTTGTGGTATTCAGCCAGCACTGTATGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGNATAGGGCGGT
+
B#"A;$=9@9@"#)-,2$B>#0#*(/7>)36;9$'=:,1#->B:<974$?F'H;2+3<!+(@4H,?90BE!!6/C@@A,!6BE**9!(2#D;9#*(1()+&6@;
@r91
CAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTT
+
6B3*&,7;&+,?8BF&61*?(0@A/3:?&84,:G3)8$#;DB/C&((8&+:618,@D,*2++6/
@r92
CAACGGCCTGCTCAAGACCTTTTATGGCCATAAATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCTGACAAACAGGGACGGGCTGGAGCGTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGCGGCTGACGTT
+
2*B6-DF"=.4F$.F)2H0%A*@;13:D@.'>1.*%C)*B7E4F$D%:GA$B(#8)%B65D(>GG=$F=?6<G/GD,%+0##,BE50)!?"-.0!(>>,#3B==->1-64'!!*4E%&BE3;09/CG262F16<99'+2GEF)H:2D-.@240@'#H+;:?+,(.HCA-3"#$4*7E>:4+&F(#,?"C)E,3)6=!1E>+'#(+!<4<?1++44@0;+#6@!3E$,.1A75>1"G6>71$&7/4.9;BA!'!&,<C&56H/#79*(8"H",("72B+<$:!7/;-3)7C7"6.AB&-H(4039G>F-4@20@(3,2,CH*!-1H
@r93
CNCGGCAACGGCGGCAGAAAATTCTCCCAGGGCGGCAAAAACGT
+
*()(+&(!!"#&&!%&'$$$+'))%#!&&*%*$"*+!#&$&+##
@r94
TNAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGAC
+
)$/1/B4>6H151H"4/!&!CF1)=FH@;5>8;/<?-:?BD1(1$
@r95
AGNCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAA
+
&$!GH#"$CH>66,@1=C1@51;F-4@2/6;H.9:'B44&(-,-E%,
@r96
GGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGAAGCACCGTCGGTGGTG
+
@9)@:,;0/F!=B,4.G,502D9#</H/857FB@?<(C@,,?B%:9ED,%70F9$21B/)>G%4>C@2>E--%B.B(8G&6>8GB-F%B?76>F=,C!9B>,#<-D112&4<(6%#A4B9#A>>9,'$F9>F.-9:7>)0E1;9%3'=$&1#:"
@r97
TCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGA
+
<1.:A@?-5%D.-,<43F;#53<$94*<CF!)4C$',/G3
@r98
GAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATNCAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTA
+
:EEC1FB3!.>%H;82:3;)*"E<;+:%!H68?29A'9.A%56C*$E%3D;7,-7754/#6.@,6'>?FF#'7G243$5CD+5CAH&/HH'<G7D'25<6!G'#@8>
@r99
CCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGNCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCANTAGTCGTAGTCATACGGATAGTCC
+
E-'<B,8""&4(9D$B&F#&=:!.HH@<,"1G4<>,C'@)+03?%H?3#"D1<E8!DE93A.C/"(%2?B-&*C5=A'F))-#G@7-6H-F2A61)'6-H$+$-E16>%?><2@EG4++D(-+?-0!5-!A.>0&B2827+?>&=6;.2C53B2D#<,.73(B9;
@r100
CAGGCAACATGNAAACGCNTAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGANAGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCNGCAAG
+
?$A(@9.(''B0H+B:0&6*6..>&6!:;">?G/.!:45,9:./87/F)5:DH$'F.6);?.3*1A>01.H+'&'7+8=(3+8$-<D*-..=E(67<D;"A0&E+B))0C/-F=)-'49/E&!&?35H5,'GF"'#9)!+C@BC7,E.?0*5'A"@7*.D.&"2&/739=!--F?"+88HH=
@r101
GCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATG
+
+"!!%*'&$!!($""&%'#"$()*#$(!+%#%)!+(+(')*!)$'&!'*(%%%%!&&+&$+($!''$
@r102
GCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATG
+
8F92@!A1#:2'(E"%2D1??*!,()5'@4=%.2,=$"$<92/50D0,#5+C96E;E6.-EH7(#FF)CA,FC)'%/5-*)D*$''+
@r103
GAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATNCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGT
+
6E7;D-+4.@=%"@>2,5+=5-0;=7A//0'6=,B"@%@;<#,#+/@$?';9>C+>(#EA&6:?(E3!>DB"<4H(FAAE$F0-//G8C<CE/#"F"<=!+4%2!#FB7,(:#C9.(D)5"3AFB$A!9HC*#)4-A'"D?A<4C.)%,G-?;0,&71?"+FD>>'.=D-983:5<%+?+@@$A*
@r104
CTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACA
+
5%<F?:G9&5:F$9@6CC;7-$EBE-(8<1*(*%6.F9G,#%''E+HA*8145-?2#")><4G
@r105
AGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGC
+
$8C%!'"1D8E34""+H#&.++9G+86?.+")8%2'6+G=C-D>!3;B%A!2=/0
@r106
NGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTNGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACNTCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGA
+
1,2"E7')@?H@"-*7"57$E6";7:>!3#&B.GFF=#$%C%6829)<4E%?'>45&B.F-6GB*)!#77?H:%8):./@E0)F23+4!<C45&4FEB)-+"0$BH%2#$/2G=@E8<&1E>H>.5="0931<G;;GD(#G&:3-$C%75(0(9=$D*,:D
@r107
NACTTGATGATGCGTTCGTTTCTGATGATTTTNCTGCCTCTTTTGAGGCCACCGCATCTCGTGCT
+
!)('+*)')#"!"+!*!+)''$#*$'+"""*!!!%"*#**(('*+)!)&'(!&%)%'%*(!+#'(
@r108
GGCGGCTTTATACTGCCCGACNGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGNTGTTTTTTTCGCATCACTTTCCGTACCA
+
8D8+*)#*DF2G!2+E-/5)@;4%&/46C:%=A,)9*",E7%;&/.1%A.%;G14$5+A2(85(23#1<8D;:"!@B?G@"'EH/*@5F%7/-(4G87B9D%%2,.C,7.)H
@r109
TGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAA
+
;2%%'">9<#@%A/-217496E5=<=#<%>/7-@82&+FB315>,4)F(683F/F#"!B&B"GF:@'/%;56&:"*"2@,E#B!6.7!EB,)C?)+$
@r110
TACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGNCGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTG
+
G??4-GD':;8$#@;>28"G!!<A&'3;49.ED=>(/9,-8-F%!C8C&7.,GF!1'4D#'9,:!7B)?/#)4%=C?<'BA"<*G5,1*!B8/=9:0<4E>8'*EDH1B')=A*>&48;-%6D@=3G#@?DB6H80068'AG6AF"(1)#-6
@r111
TAGCGTTGAAGAATTNAGCCCTTCAATCGCCAGAGAAATCTAC
+
@4C4*(.8H-;1/=<9*060$A(B":4.FD1;F16*='0G968
@r112
CATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTG
+
>(AHB21.(!3#E;6D!5+"4A%,!F2B4=B9EG5/:A31G)C)%7#C'!H7.4*C<+@9;4+@2$*:A556F/#,>3%%,-$=E7<8E!B2G,3+6>#3EC/9'B7%7-:7(075)$'5.(-AE)%+<(:=,12"6!;:1@?$(9H=%7H.(.F2E7,1==<=7#=@5D0H$?@,B:"3CD""!
@r113
CGTCAAACATTAATTTTTTATGATAAACAATTCCATCCAA
+
*!+'+)*%"*("+%(+!'#'#"'&&)!#+(!!)#'$(+'#
@r114
CGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGNAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCA
+
8#?BC=6./>D::D-3=DA/)#5;A<;3A%'C@./%.4,82=7E0$28*(;AC&:A>8;(1412>&.@1E-2%%8!/<#F6D8/98/=-?#(./DF'7:'4A"#8A56@D'@@+0#-H8.CD5+G2&1/G
@r115
TCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAANCGGCGTCTCTTTGTCGCCAAATTTAAGATACTG
+
3=+?-&E518G)94752H!-&F'.E@#F4,1+1$40<5F55*0"417=26A1>5*591:3*D48F4-E*<>'10D?)A)53G
@r116
TNCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCTTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCNGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGACTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGNTCGATGATTAACGGAAGTTCATCTGCNTTATGGGCNAGGCTT
+
GD3;B.-;<)=,=797/;7$:@8>8879/%3(8+036=C0'0C*>:-'FDF7:>B@+875-!#*?.,HC@@,%H>4FD-C3HD*:*E)?H)7*/9&=)B8&A<1/8*@8DG4$"31E(8/-%&BC<C&4B0CC@1$'2;2B0)F">C'F9#9!H69=;!;11!>G>5%*%0)4?!&H9.B0H-1*"&9@9/G;,3AEB@(-8049,@)GH(</;@.'"3#)@4=/;+"&@!*(C
@r117
ACTCACCATTACCGGATANAACCGGAATGTTGACCTTGCCTGCAGCAACGCCNTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACNGCACGAAAGCTCTTGTCGGT
+
EAE,G=&D.+%45+5H?F5E:D*>C0-?90>.:H?C<E,5,?++$@/@!-7/>#-E1"6?05444582-42.D"3!498?D-%%C(HB8;++5#19.E#$&$76DBF3BD),()8:+11*">.8'4F;;4:=+
@r118
TCTCTCCGNAAAGTCAGGACGCTGTGGCATTGCAGCAGAT
+
2+<(+@0C85B?EHG*7C>.:<95#,974#5",G&<GG;D
@r119
ATGNAANTTTCCGGTCTGACGTACACCGTGCTCAGCCTGTTTTT
+
)$*##$'+))'%(#(!!*+))!"("$(%%!%%+*"'+!&#%*(*
@r120
GAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAANAGTGGAAGGATGCCAGTGATAAG
+
:78=F$5+C'8@5@C<6B)-):H1?F3?51-1'+88C(BEC:&-:@A4)004B>5F)!G883,01&5&,G@B!GF6H"??H)>0G,E)"H/=))=,.;06",;HG
@r121
TTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTNACGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAANAATGCTGCCAGCAATAGTTTAAAATC
+
52(-$FGD-#G98./9);G22GA"29HH+-6-B6$:HE,/)A7#B&&<&'*.1$1*99;%/%('D,<8.@3:-;C*ED?'90(8CC*(+3=7?4H#5H5,+G&+*(%2F."FE77==,%>:1"A<%7,CF.%@FH
@r122
ACTATGTCCACAGCCCTGACGGGGAACTTCTCTGNGGGAGTGTCTGGGAATAATTAAAACGATGCA
+
:"<=39>7@;+33*"85F$G-=.@*9+(1+#>&/8..'=+C34(,#!1$59(12$##+4!"2H'6/
@r123
CCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCATGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCNGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTANCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGNCGCCAAGTGCAGCCAGCTGG
+
">B"$?<:8':+-FB4=/304#0):@#(F2-A0$2H1,;$?DB8"#@)3:*6CA'C%!:38($GD":(H?$C+#.>4&F>2&)E7*5$'><@2C7!@*#..5,39$A&:C)81#D9$0BGD)2:?(*&9G36D6"<,D8?,(&56E:G=AD12>4F'(-(=0E*.H"/%(G@GD1B!!2'8(;<-5=$?,@7+&&1=F$$46437$*5@FD'GA>);@*26?)+:)0<9!':F*""/-C33&G(:'2*#";*%""&##+:'5+:*4#&B2@@'5$!0!2E*:0%;#H2B"&'()-=D!3#C*/#C(!*"=G.5+%A46@A?)7AE;8C2!5;6BC8/#!/&H>BFD6;3)D+"3,3(.,3AA;E9>!CG@>51"+-&;'&(*B:3=->FHA6?5/*0<&9;20,E$#D'(/1&0,'(<+E.'C0&659-+25"2E*@$%4=:0>6*A78E)/'?69+)((#&+*D5$(@")>79@A
@r124
NNCNTNNGNCTCGGTGGTTCTCGTGTNCCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGNATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGCACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTT
+
%#%#%&!+'$)()"*%*#&$'!!')&+"'(*#!"&)%"+)*')%!#'%+%%&%&)#"$&"&!+*'&#')!&&+*$(&"('$)&!!(')%+%"*!#%##'+'!*(+*))+!%(*')&'$%$")'*%&'+%(++$++&)%!"##*!##$(#**%++**$')+)$$'&)+!)!$)"*)(+"%+&
@r125
TTTCGATGAACTCCGGCACNATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCGTTTTTTCGCGTCACCCACAT
+
12%8,13<F,803>"@'<(D)B9/03A*E<#;542?->F/4?E<-3'3=+;/D(;D81#D?;EF*.D%4;BHC(//.2A07!.)5BH)AB63!6F2,7%22#$2:;8(?4<$:<4>+..'1=,=)1(286+<CF;:27/<5!
@r126
NTCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTAC
+
"'825#C+B)/B=#7:-D%)6,F%AF#7%9C,*)F4-+94$(1-+=*@*:,)FE;%5401(F2BA3-F?@&9&;9<)>51'DG"77?G5G-E#54.2&2/7%/$,'@4'.7>4C<
@r127
ANCNGGATGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAG
+
%#''*"%!)$*)%+$#$)+*#*'%#*&"*)+)'%'"(!!%##")#(#((+"$*'+)+$(#('+))$*%&(!('!!
@r128
GTTTGTTTTGAACAGTAAANGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCG
+
91EBD:6:H*%%17,-FE/,&,$"3&*<C#F;5EE=%<B'28'H,=%43DGA*6;:)
@r129
NTTGNTACACCANTGCGTGCATCGAGTATGTCGCCTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAAC
+
&@9@2A&7-)B#&C.#B1:>4(82(%D0"(>1*)FGH3"+@.&GD.$,'0?1$>%4E>+4)=B0200G#G,*E@5/@,)@E77.H+-'"B9D3H=8%&;?(HG<7.C>G8E"C%!5#05
@r130
AGTCTGTCAGTCAGTGNGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGC
+
-7C;4<4@#6F>'"=>.>7:6H3"D/,:2=),=<+<C)@80&!A08;/+7$-D4
@r131
TGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAG
+
-D!A59GE*+D$B?4902?E#3F2E6,</E4%?E?%6,F/!EA/$D3:"BE%'F#8!=5?B2%:F31-40-.2>G6/B>FHGEC
@r132
NTAATACAAGTTGTTTGATCTGTGCANTGATTCTTATCAGAAACANTATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTTTGTC
+
#0<0-4HBE%8,!>D,&F8$9CH@G9,>/1,H#F8&);;C<F9@=+7<2<F!+"3@G#'3<,;=?&%>/>E5$<)ED'%-DH*1?G/,61<@//!E>1"1-4D
@r133
CCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTNTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCA
+
4&D?)1*#5F+-'=(>8!9=4)E&4B=%3.70#B22)1-(C%4CF=,@A!G3E@@7'F!$G#H-)*;-8>#E''A*DD*.E%#=7A:!6?,D:,EF:4CG<6%7;)'<1-!C)21;1(;%=D1)#/=G+D'18+!&>)F-2.,1FA2?//&D&.'@C0;6;0#>2"-:>'7-,EE;&&9H(C,59)4)C'*;:1'?%-:E%<A&'5G%0
@r134
CTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCT
+
):..22H1*E&*:9:$#B4'()&.0F;$A$;47.CA",0E)?*
@r135
TGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCA
+
=%;FG7D;A'?9ADHEH<+'#>DFC7BB%/4"H/#1;=0C+GAD>7'*HFHCC3-0"(B*5!A**8@/.541!%.E<'@81.>%F.$((GE
@r136
GNGACGGTGTTGCTGAATACAGCGTATCGGAGCTGAAGCAGC
+
((-;7;D3'F=(/A5D0>+/*G@834,,,A+5A43E=<9)*1
@r137
TATNNCNCATATCCNGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCNGCCTGCCAGGTATCGCTGTCCAGCT
+
''("!&&%)'"#*%!+!*%$(*"(++))"$)"#""((#$!$(#"#+&#*&((*+$%#))%""#!#)#**))$($#!!&%$!(+#"$#("$#)*&&#+(!%#(%%)&*&'!(($&"##%&!
@r138
ACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACTAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAAGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCNTTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTAC
+
C1630F:(:(!??//>D/4=-C>B15E5A'8A",)3,4)A")C"67?B@5-&;,+';&0(F2/>"7"?7C;A)+,5GGHFE(?/8F6*107).F+(!3>B<:)#;=28-EB!'EG;G;/4??"GAE?$?0B;;?8%-&/0,48,$0-8<H+/6H#-@'0+62<FF;1DF*1?!'D4#0;60:F$7D$)B,!&?0+#/?&"*#;?H7/;/9#=.5@;!2':)/#69C92H?H/.8"G)78+6<!68E6CH@$%A,%<.$);?*9BGB:5/18#B%(),-F9,@A8//88>4%"3)B!A29BE3<.B1?<(,<&?/%A#6B<*"A@!&C;?2.!5;!@!'.G*H&@1/++-$):!6
@r139
GCGGCAAATGAGCAGANATTTANGTTTGATCCGCTGTTNCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTC
+
D686D;8$;*!B)H*>8/?4C%?E4;:-+%!+42D9B"5C*0*H?D6@!:&%,HF"$B!B4=?"&?);'"/8/F:#@"@H)G8@)-B50=(9C
@r140
AGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGAT
+
BC$#/"26?@3,D0C#DH..<9%:.42*1!-"BF8*<$4<@@B,$6&>9
@r141
NNTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCTGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAANGCCAACGGCAGCACCGT
+
!!4A:7.;5E8&+)>5F&,>C,;#H87./"&9,&1?#%G,9H&E?*2"B2A=<G>5;G'B#/'"&<)#/(E8FE?A,%;;A!HH,)$E69-*/,'%B4<+:F+>DCD"->:CA-5G0&,#
@r142
NTTATNNTCNCNGNNANNATTTTCATTGTTTTCTGGGTTGGTGATANCAATCATTCCATTCAACATTGTTGTTTTACCACACCCANTC
+
#''&!!&)("!$'&"($"('#$+&*&&%(!((#&$#(*###+#'"*"!*)!%(*++&!"''#$&(##"*&&!!+&(!'(%$$+)%#($
@r143
NAANNNNNGGNTATTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCG
+
&&("(%"%#%"$$+()&'''"%'!''""+"!!"!&#)(++!+#)&'!%**(('&*&+)#$+)'$&+$)$+'"*%$*$#&''$*(+'&%')'*'%"('#%%!$$%%$+
@r144
GAGTCGAATGATGTTGGCGAAANCACATCGTCACCCATTGGATTGTTTATTTNTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGT
+
D=@4+$E?&*5B0G%3>D.*C#87D7'2=*2$@4E3.=1F%6E;!;6-9E>(13;#'/5*<<+7#D&B,!'(8C(G+G&F>C@470:+A@$.*':*.C&*"40=A.1/9/>
@r145
GGAGGGATCATCAGCAGATTGTTCTTTATTCNTTTTGTCGCTCCAT
+
-B<,'8;#$=!#D1-082?3;9))=!$!B$8HD1#<$E$#9:.5/#
@r146
TCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACCCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATC
+
C1DA<?"*.71C<5:*+=+'G,03/%%1+G:;-*.19@?3#@D.%4*$9G'?4+;8,7B1,($)7DF(%&,*:9):C%E<#17=)FB4@!B*-4A1"E?8H4<":8DD+8+*AD&E.:;0>;,4EDH$=EH(F"#/)>@/H59D1-G@"8$()44<>1@=4%1G2C=(G-9,:C#B4?-,=%.,7B97()AH%D$=D&@-*3?C!AC6<96%/G!76.(,E2B=9;H4&B+$*-D4=++($'*&&4+F%1>2!4=(.8:%
@r147
GGNGNGCTANNTGANNNNCTNTGNNNNTNNNTANANGTNNTNTNCTCTNG
+
"!$"$$"##!!$$!$"!"$$!$$$!$$##$$!"""$#$!!"!"!"#$!!"
@r148
NCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCNGTGNCTCTG
+
(.8?(=;9-!,$)69<47-(.(A$G!@C-F?'1%EH@*D&@1H0*5/5?43&9/"2A8BC2B/(A:-,+E>/%<B(,24!E1)="=G3'.55!9(=0%H!?>5'!#!!2!5FG&@$/.G;HB%.8H5)H;;8<"E>-<4=E/@"
@r149
GTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCNTATTTGAA
+
EFB8-A0(C!;BA,!8@)$7:.:,6)"C4D29:,CF1B2/-B/=&9A61"?*@!.D!%-+2758D4&5F&(>C>9%
@r150
TCTGCNACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCAGCACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACCGTC
+
+H+?8&-#C%27A&!.?:78"HB.&D1459G73(=!G2E!4A-7%,32#+1'&2',),1;5)/)'C>H!E%>D9&;E-*:3+;HB68$-7C#0%!E17*(&&F4C<34=+9&!8C2"A80(#599(/HF6>C#FDF#&?!;#H@-1?-4,(H3;'6/2C7?*'#!B9(!.@C.)$,5>+#:9;11E/5.7'4@A+8#C-9*3G-B&%.:=B$;?:+4&:$(:(.#7D3
@r151
GACGATCCTGATTGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTANTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTATTTATAAGCGTCGACGGCTTCACGAAACATCT
+
A?@3C#7=50&)"C-GAF(B3$.AE,5825!=43/B./@30$=:DH+)AH<8D1%<0;1D)%D2?(6*;"?6D8:F,1&=3%-"+A>B3$):G)9/3??B)&=2!#-(.=<A!;27BC0*8.D9/,+%!.6'AG>(!HGD9C&B17?7*@G#>)H.286/;(H,-''1-<3+$41*3>BG"(
@r152
CACGCTGGCGCGGAAAATCCGGGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTT
+
+$&'+($'#*$%$)(!"!$*+'$#%&%")%"'!)+)+*&!*&")&+$()(+$+(*#"*')$$!!#+*+$'%+((&&"&+$"%(()'"+!*+"(#!('&%(')*"%**)%&!''&%'")"&'*#(%!"&))"'++'((+(!+&##*+&)!!$$!%&
@r153
AATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATT
+
'<7EC>H=5$)=H7C2F?5%&3%4H87'?<B38@6,2<B+%#3'(DE="F-CC&(DE39?.E:>&+#*=&:;?-''&8&=5"2#=%&GC!-7A1:<)!5).#E-4B$F)<6B7*))=*E;&0=.
@r154
TTTCACGATCCCGTTTTGTGAGTTGCTGATTCGNTCGCGGTTCCAGATTACC
+
:0<8A=?'>:&85')+:B&>B#C>E80#32@$55HD;9)64.0*-93(*66>
@r155
CATCCAATTGATTTAATCAANACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATNTCAGAGCTATGNCTCAGAAA
+
,!1)-'*8F"4,$17G$(HC4>=>(B%?F(%0.3,'@8;3*41('86EH9,F(!).B&&*+:C6:7AB)1,CB!EDC:D>F/>+?'*>=?2&)=9@>3.8&>A>6D%A3G42;7E19561#A$'H'&840<7&-
@r156
GCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGGCGGACNTGTAGAACGTCAGCGTGGTGCTGGTCTGGGCAGCAGCAACCGCANGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACG
+
;;E0(G9/8%::8+)12/=?#)<%C0!#<58#F=E.'<=%F@*-6(08%(#G43B#..:3/7(HEG932G?.+1B,*#'(>=B>&"D$%);5)+55(635<@B:A9B+A.H:'!69>:0?@55*75$)&C"+6@E'GG+1).D9!7,*!>F9>#;=9
@r157
CGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCT
+
>>?-/*,)!=8=D/)8/(H2>@+&?/A$./@7->>)$$041<08G&%GF-AF:'1$8?
@r158
AGANGTCCCGNGCATAGGCGGGTTCAAGCANCAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGNGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGNAGCCCGGATTCAA
+
)#%"%"&(%%!)&(+#)%("*)!$&*+&'"*%!))!+"%!)+*%)%("#$%#!)*%&#"((%!($"%%$#(**"+"'&)"'"*%)%)"(*$))*'*&&*+''#"%'*''!*)+%&&'!!!'+$#"#%
@r159
GGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGNCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCA
+
D>",A#,)07D+-/+5E?.62"(3=#E"E*9E/C2;H#=*:%H10=.*,$B"C$2"!>AD=-G1/%G7&HC1='6+8A5("G8.0';ECF=9=.A!5<#(.#//#D,4#!!!3)EB@AF28'AG7.>"&>'.9#?))4G
@r160
CCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCTGCCGC
+
'A3C@.G<#/:%);1"$?.5%4HA!-9.),@/B-":93;#F&&61<,//-/+>*@);/
@r161
NTTCCTGTGGGTCGACNGAATCCATGCCGACACGTGCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGC
+
!&"(++)+&%&)!$)&&+'""#)+"&*$*'+)#$+%#*''*('$)##+$#&(*##!*(#(*+'"%&$"))*$!$''()"#)*+&!()"#+#'$#+()#$(%$(+#%+*)+&#($&*#
@r162
ACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAA
+
F?&-,@>%3"*<+A/H25?EH&H*/10G#*%7H'%1(CCG:?4B0)@?!?2/(<:-/>BF;+%/4:1@&;HB:2D('>9=/*-!",37$>E28@!+8?6+)H!:'<-
@r163
TGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCANCGAAAAAATGGACGAGGCACTNGCTGAAATCGGTTTTGTATTTGGCGAGCAATGGCGATGAC
+
FB"($339H%:E.(+?0,"1D!=CE(>:6!%<1!C=C0!7DE:4BE'97B!CHB+8&';#=:F%>.C:$>9()20GE:DB*?#3/(G'.FFG4)6.(&&,14%2=D9
@r164
AGTGCTACCNGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAATCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTNTTCTGCAGGTGCCNTCGAACTATAACCCGCAGCCGCGGCAATANAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGNGTCTNTGGGATATGCTGACCCA
+
D+(!2G5*D?::$'!!:F#F=2$3$G!0(;FBD(#4(D?%<<9?:9=?&?9D/GH$>157)+7.1)>F5@3B&&A'>C37H=--,F)'?7#@4H47&86?";CC:)H%$F,+'#36!5!#E*>2H'2=,,(H7/E@$4!#$")F#$'")H?C80C$D($3;A2C6(*/:2H1B8C>!!C#2H/&"$E0.>2472C,G!7#=(2&;F,++@
@r165
CGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCG
+
=4:H"G.AF;;/A119<A/C3!%<-%/C@2A%&9?---4F'1;3/&8.H55E"A7>C*0B>4E3*$H2*+7,%(88D
@r166
AACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGGAAGTATGCGTACCGCCTGCTCTCCCGATGGTTT
+
<"D+4;592,7!B@6F>5B#.=C.;9:./479HH?<CG"C8=&9#E&;*+&)'9@D)(1%51)&$;$1)<))*AE31=/,%)'.31'E90&0*B>2
@r167
GCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATC
+
$($&9".>9@&/=<57'$3?%7G-A27#87+15F,=/1)F0>5A<;FD/*,@10
@r168
CCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTT
+
$,1:4%6-!FGC,@:F/<("G+9-?6@6??+$EEG*$08)1
@r169
TTAGCNATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGT
+
(+FB(+*.!2&H7G1A:59H$6>=.?B7@)#3"C/&G!%;80)55%>!,+24*.;.6$20<3-00
@r170
GACATGGTGAAGACTATCGCACCATCAGCCAGTAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTCACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCC
+
C613<+D:HE(.))D,719.%"4."A..B,/>'*;;>)5("A&6%CC>/*8@?$652:?E<;)CAFH(6,?70A@1:%?/)%D42)C/<#&##.$B;A1"@$"#5C!(6?>&G(44:#E1>).7&39&'8/#'5:+0&9D#=+85.H&F'@--.)$+957DD)"A6(
@r171
NTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTNGTCTTCACAGCGATGGCAGAGTCTGAAGTGTCAGATG
+
#+$*%&%*)'"!**!$'&$"+"+('*%$*%'"$%*$&%')%!)"$!#&*++"'")%%*!*)%##"!++"+##'!!$&'%*
@r172
NGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGNCTGCAGGAAGAGGATGGTGCANCAACCAACAAGAAAACACT
+
%&+'%*!&%&()#*+#&%!'!%((%+"(!++'%&'!)(')#+&$%+!*#%%*)$(!)$+%!+#*#&*!+!*$$$#&'&%&')'*)%'
@r173
NCACATTNCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTNCCGATGGGTTACAAATATCCATGAACACAAAAGA
+
+@+:<,3<%'0&(4H7-1D1<&B7-*;$)"#-4)/"7#HA*"3;H1B"$@+*E@3#ED#".+5+5(!+9A+91:E=-6A-
@r174
GCGCTGGCAATAGCTGNTAATCGCTGCACATTAATTGCTANCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCACATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCAATACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGN
+
$)2+(!=-3&=00F1$F;!2?):.>"FH'+9/*8(&>:D-/)*#,+H&H-,1$5%=H..G2/?*6-C9!D=+#!;C#06D)#GC*,0=')D/AB5>4)7<EC?AA$'3-(##@#,)9?E!BEF#9E8>#%-A"$:-:(9?E?9(=)2EC9(H7C#251AA'?5=*G4+':,4(@53>C</>''/$H!@)5:C-,(?5:B&,9B5D***:'HB5#=4H",-+>F2%ED.1?-(*A!E2++231*-#)=B"
@r175
GNTAATCAGTTCGACGCGACACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCNCACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGT
+
)$+.-D9EA81.#A&+/:!+'-6!G3C=.+==6%+DHG//6F-A)B:G",#=D1D7/$$F4;B@#"@(H4H,*!?HB.%>47#*-)(>&6)..07G43=2-G=
@r176
TTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCA
+
(*+#*+*'!*+&")%'#$#**$%$$%*)&$"($!(#$"#"&&'%"!'!'#'!+
@r177
GAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTC
+
3*;GFA'4CG;C?=#!/0$(D8F)B:8E#.C1**.+,(D9+'&;8!5?/4?;F-2)'+.
@r178
GTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCANATGTCATCGA
+
):9!8>(4),<)3BE7'DD;&BG+63D&).F8+5G3A;AH*#B'<$?5801176?4!B5>A3)$+D0$!,
@r179
GGATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACG
+
&(=986;E7&<).6<C5"20951DH9>,1$;-*!/H06G"=D0G,%H8!7A4472+
@r180
CAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCAT
+
57)*(2:C74'%"/F0<EG442G9!@%C%:A8&9C/?F:&(?A8"6'C2
@r181
GCATCGGTGCTGTTAACAAGTTCATCAGCNAGTCCGGCATC
+
1;<&>7!+G*!F4-7+@D8EH%>&'1:*;:/($&&G89!3)
@r182
CTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTGCTGGCT
+
H:#>-6@;4C>#@157(@@?%H6"E)4C.%:?:FG=9D?:G9&=4->
@r183
NCAATGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCNGGACTACAACTGCCACACACCACNAAAGCTAACTGACAGGAGAATCCAGA
+
!%'#&+&*%!"!#"*+)&'+'!(&)"$#+)'***&'(%+*&"!*%&!'')$(!")')$&#($&&%+"((&#*+)%(&!(#!##&%+%&#!)(+*))%$&+'('&#%)!"')#$(%
@r184
ATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCANTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAAT
+
B8C9.4;C3"3/6#>#H<88,:B73:,-!-*0;8&E-AE77;0AA(("*+4D,5#18%9*<G/F3E-(@(4?=$>28,53G++F"D32A(9'#82&:<<$((/3<+8FE-<%&B9459!:4B&:D-*+7=+4"C@C2E%8<&716.2."#1D.=GA*@'@&5;"(
@r185
TAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAANAGTCGAATGATGTTGGCG
+
8H!)"86AH5<9(-8)$?%#%.0#,&3:.B058#D'+)/6/3,"A.=)'<E@'10CD%
@r186
CCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCNGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTC
+
GC0-7#;36$G,,2#7!"@&!937EF;A9&3H,B:5.?;6.B&#.B#,=*D(8.+G$(/B9DCGCC/@)A%0&:67F?-E!#2(<>./?HC!88)>8.;3GE#@,63;.'@$2,1FC1H:20<21?0
@r187
TGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCNGAATGGCAAGCAGCACTTTAAACTGTCGCNTGGTCAGATCTGCGCCCAAATAAGCCTCATGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCT
+
6%$14FFD>9(%6&?0"AC.,>03-B78/%/1F0845BG-2.46;F&!4EE9,9<<CF,/,:2@@D;,$0&4+<4!EBC%@<9!3HFG&06/69;1#@D&-+<!EDHE6H7.%.<@%,*?48%7!%#3$;DA-$4&!1%87;=>*DD%1D>D=@-A1.$H00-00$B+A5)@-<'C82%"H8H(H>13*1!10=905-,EH#-4)5DD9;:>/<5$$B6/'=;1,G*1,<1"C$7$2C2H42E<;
@r188
NTCNCCANTNGNNGNTCCAGGCNNAAGCNCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTT
+
&)'!##%('#%#!)''"#%#"%*$$+"&''(*%%%*&!"$'#+%!$')%(*%'*"$+'*""*+!!**#"!+%'
@r189
CATTGAGCCTGTTTNTCTGCGCGACGTTCGCGGCGGCGTGTTTGT
+
F,0%+$$*7DB/=C?&/278%3>7'$!<.:+D)>:#B>G<&5%0%
@r190
GCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAA
+
G4G/2D2<A3;*4=$%<G+06<7'G/=)=2FAH2C%2=4D6C7@;=-3C&).3HHE+!0&3F&=8A#+)?#CA
@r191
GAAGAGCAAGCGCATGNAGCGACAAAATGAATAAAGAACANTATGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTTTAATTGCATGTATAGAACA
+
G8*8$'2'*F=05E:0,%@0!0E%>6+A9&$<H8>2"6+'&=D($$.9*+<'#97F90%@F"3,;0F$!%+!FCA'E5/9."5#$8"//"!=;CH'><>C#5/2@&5+#;@)H;>H71>*."4<8G"=E!6"0'+;(!B72?
@r192
CACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCA
+
,B9F53;G&-A/*DBEED##10CG#'"@H<'+C%=)&B/AD(+G78;!H5>E:"4/D!)"00:-F$;93#CH%+*!H*&H)96E)(?FG-HF-1;=.
@r193
CCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGC
+
B/?$+3.+3C=4$"':?B=#/)H$<-/>'(;@@:<**8+B?F++//:8&3450'')C=B)E26.'+!";=%,G?+;7/>BCC"4=,!6%1098HEG0F,
@r194
ACCCGCNAGGTCGCCGCCCGTCACTGCAGACAGCGGGGGATATCAGGTGCTGGCGCGATGG
+
:8?!C?',6+CD)&+5/.+-0%/1H-)D*$?/?+G2A080G)/&AEF$3,)?E=078263G
@r195
TTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGC
+
@$3!)7?+B)9+H7?.)?-0#B!0*@.,,47@A-7(,H/D9G@@':%(>4/E?</&>G8!1;8?3A+E,H$!G@#,A<E#9+;C?CE6B)A
@r196
ATTACNTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAG
+
-.?:"88H%#=:93/,#&2*$?@!AA7/EG1'FC8GBG:"DE
@r197
ACGCATTTGGTGANCCGGTTGTGCTTCCGGTATTCGCTTAAT
+
#%&++'$%"'+"%*()$"!!($)%*($%(+"")!)%%($)!'
@r198
TCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCT
+
+9#;67D5-=5>E2'C08%&)113;2.*FD,,4/@!27<>H8/;+&+13@9
@r199
CAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGANCGCAGTTAGCGCACGTGAAAGCTCGCTCG
+
&3*-<:';('G>5&%0(A#4/41A8=#;E(+&G!;<.:E&(;(*-E7,/>!13.A:$@6;,>>1A61<",32A)G6(D'H!+%)*
@r200
AATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACC
+
)*'$8)F7*F00!50A=#E&DH/A&:@.%C96<>.$=-!E/'E3!71$
@r201
GACCGCTGAGTCCTATTACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCC
+
0C+;6495A+H067A)161(%0+6D-C!)8=:G,;<79:/B.(,?C%.4*+8E'0<D,&D(C39!'B.G+">B>!:<.5:D#
@r202
NAAGGTACGCCATTGCANACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAAAAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAANCGGCAGGAGGTTGTTAGCGCGACCT
+
$15##-,>EA.:":A&$F=.=688F2!%1BH1"2)'4.!D#-'>+97*C(6974@E?>$G04@2A48+%923/@+6HF;F'#E-F&<@<-@(;*GEA6"071</*F>";EB$!E*-0<<*&5B2C(E*<(1;<5A*/&)HE8+/2F!A$?2?B@7519."2'.H<;,2#D=<,(5A,B$'/$7!*1-4832>?#>$?46248290C;436@E6@"?%&"29<56F);AE17:-99,8=<'/;+D:$
@r203
ATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCG
+
8@'6?80GG#F:>),8;:1FG//B#?AG>C-6)A5,GE?7"&.79&"GA-*'"'H#!?5H8")F=.!$3:E
@r204
TACCTTTGATGGTATTGCACAGAGTATGGCGGCGATGCTGACCGGCAGTG
+
!#&#+#%(((!%*&+('''('*+%"$"$)(!("*''&""*!!#$#('#(%
@r205
AGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGANGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGNAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTNATACGAGACACCCA
+
-3.F5@+.0/<:7@)E!@<D13+92"'*%1;.H645D<-3)131.CCA?)A5.<;AG'#:FBG/!"-%C/$!H8F2EBH/79C).68!"2B3$7,%8-79/B,"A2=,C@#$G#D(=%>-)?07@)+*!:(@,<E2,*E0G-B00:1;1/4'%,,%G;B(9@&A#+G6H%%AH4"&=H2GA4E'926/DF=$H/63CA731.A4(-4!66>>F'%9A!>C*?*>344G?4@4*E6-&
@r206
TGTTTCCTGCCGGNTATCCTGCANCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCA
+
@5.(G*8'6F+>;F672(#FF?+=+829+$(<"H2'6F+2=$@59$!./2>-#"3C,@DF
@r207
TATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGC
+
%B!@C3*836<5?@(5G4'B447$67&)%9<&6?E7((3BD/#C@
@r208
CTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACG
+
&/!(*8:$(&#H,C*B,*).9/($=,;7'66;@?>>?"@):07D=3:F4471-B
@r209
NAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGA
+
")H#$.?'9+5**E#'7:#A?1G-H3!BH924B4+=9@<4)DD/8!GF':3G9/H%=&<4=&"42!4&D-D)/<D$.DB1,+;&GF,#14
@r210
CAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAA
+
/<,HEC-8>#60@<7#&$G$>E?8;-$0*%/A7@@%!!E'D0,)E0C3B:B,2(11>&B(@1
@r211
TGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTNGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAANGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAANCCACTCAAGTTTGCCANCCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATNGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCATAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGANCGANAAACAAAAGGCTATCAA
+
+*)'*!)*!!)()&&()%"%*(#*$++##)&)&#&!++#')#"&"$(!))&"+*#+$%&&"$"*+!"%$"!+)!+&)!#&%%&*+)%+!!$'(!!*$'%)&$'"##!&*('%&!')"+$$+)###&++*!&+$#)'*&)*&"!*!"&%&")('!'('"$%!%"(!&"%)+('$+!((""!&(#"("((!*%*#++$($!$"%*$')'*&+)$*)$!"(#()!'(&+('$&&$&$#*#"+!#)!*!)(!*'$&'&+'$#*+!+!&$#!%"+"''))!*!"%'+#'!&!&!(#!('%+$"*+*('*$"!%+$&**(("((!*!*%*&!)#%"#)!%)#""($)#"'+%(#$'!**)"*#)%&*'(#**#*"!&%#&'$$%&*$"#!&"&(&$#+#+&%%**(!$###&)%&")+!$%!%+&*%'+)'%!%%)"'(&''%"%()!$()$+$%!#*###&!#%!(
@r212
NATACAAATCAGCGACNCTGANTACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAG
+
'$5(08-'>'/99+,=05=%,:H'4(+2'D@+@':9")#84-2@#?2;6H8BC9"D,95,)>;866:FF<*@9<";"/A131#:B.81D:"2:21$>!@-27?&47FA>
@r213
GGCTCAAGAATGCTCCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTNATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACA
+
EG1$C%9;"5/@(<FD<DC4&'+<<67@>!4?'AF)'")D?4'.3!:06F;%,!?),"F::->0)?.&>>1HF?&;,?>6C37/C*GB/?08D>=)$@82+#2
@r214
TAGTGGTAACACCCCTGTTGNTGTTCTTTCACACCGGAGACACCATCGATTCCCGTAAGGTTNATTTGGTCGGAAGCGGTT
+
2"H9A%A#A3(5%@DA$0F4.%+$0+-3*>58!0E-G,78/;80=%=?;-7-&7GB0&#3&.:>?-0G;:ADE<E,BED6H
@r215
GATATGCTGCGCTTGCTGGCATCCTTGAATANCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAAGTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGAAATCTCTGCATC
+
<4C7:6&=B1$71@/85;2B52G?2.$.E;-?6.;'<B=?0;5F&D*50&%9?0BDAG8/2?-1#2#&'$&+F?7(6&D#&,#"17C9%?;/B7=)-2B<*+&G*3"&3!A7=##57/F36-#'")=@GGE-63%
@r216
ATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCNGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGA
+
<80@.>"=BE5?/+E/B-3='=.9!2#;$62@,/7?11@;C:(38;<"+5?B':"$*-/,)G>(=@,2*.:4,.0,5=64.GG9>8"?2?*5C9%H#@1<''4&E&,&&:*
@r217
TACCCAGATTGCGAACACCGCTTTTGTACTTGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTG
+
1(/CGE0B!43)")+H,>9F:/!6)6:6G.E8<0%F1%;C?07"<8@BA"4?EB2A-&2#-=%H9<0AG'/A(#'H#H39#7#HE1#A@#G
@r218
CTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCT
+
E(&(*#".CA>>(.%"+-6H!H?":E6#+E,.58BG7#G6<:+:+793#+06%90.2!(*<7",72#48A"<E+(EF?:#1%<%0<(1E2*@1D
@r219
CNNCGGAGGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCG
+
$!"**$&"++)))(+&'('*)%"#$)"+*((%+)(%)$#*)+(#($($%!*'!)%
@r220
ATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGG
+
7)?=-5/.78<9F-9>7)@9363>>A46"/)%73*D#3=,3?,0'?%@HG"!1C969D4=5A?%1';H30H7C*!CB5'2H
@r221
TTGTGGTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTNAACCTGACGAGAGACGTCACCTAGGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTATGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGNTTTGCTGATGTGC
+
'"#)("('+)!#$)*%((('&$'+"!()$("#+"")')+$'(#)**+'!('%+&)%'"+&(+$($*)*&'"$")"'"')%&#&&!)()'%(&"%!#)'#)'##&$'!$%($+%%%!$'%*&(()*%+"$"%++%()++#&(""$%*!#&+#)'++)#!"(*&*+"$)#*))+$))')(''"*!()$!)'($'"$%'!!#%+')*)$%
@r222
CAGCCACAAAGCCAGCCGGAANATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAANATATGCGTCACCTTCACCAATAAATTCATTANTTCCGGCCACCAGATTATAAATTTTTATGGT
+
+&!*!("$$%"$(*%#**)&!&)($(&)%(*#%+)&+&!%!%""!$***!#"+#''"$*%"+(#+#$%)&"+%!$)#+("++$$)$*&&*%%*(#"*"#*()"!)+$%+'(%)$"&*)''%+"""!*"++)"(&$+)+!
@r223
GCTTGATAACAGGAGTCTNCCCAGGATGGCGAACAACAAGAAACTGGTTTC
+
4?/-:(+$2AA)+;7!09@)<60?"=.6@D2'B@'-31G3.7E$AF*3D(>
@r224
TTTNTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCC
+
G5**>3G=C6/+@-)#5CCF>9GE/+&2504&8)2'$-;ECD/+7@<27AF)A7HD>37D6CC,D:6H+@=<%CH9F$H.C*5G!$B2@0)@3CFGB5
@r225
AAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTT
+
/@2":?A*!'*86;28G!C1HD=(H5#&7C>0%D(6(EF<":3!C<7))<
@r226
GAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAA
+
=561(9A0?*E61%@8)CH@:FF)"B1G2-82-'B;C&%3'H-
@r227
CGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCAT
+
>98%:H5:552#);"?$=#ED"2)@?$,A997@.3$6<,,!(35%92$8?.!;>A5F7+1B:6)!")F:3)9%/)/*#@321AB%$EB?03;$!(
@r228
NTAGACGCNGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGGGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTCACAGAGGTCGGTGGAGAACG
+
$#%5E.+@)1=9'=.BF?,&:@.(!7#.,.&A1#&),00#E1G:=EB>0B.0&<0&C+G;>C<<D7=>/F*G+D#3!&'$486"+;0D@A9A-"E@<;F6E2),;FA?3$B!/+G./'7>A8H-99B%%0#*A4+,5/>7%<>9@!?=>)<-;$C))>"%C8A91*2F6?4%5;48,$*D-1"#<GC;,,.5$/H9$1;13E<@1GF=6!)HB$CG+(
@r229
AACCTCACCGGAAACANTCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTNTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCC
+
:7D*;3C"#3C:&'G&;64>=%$1@&=C5*HC.D?3@';)-&!D20*B'2=7.D?$22A*:+6A(<.)-8&A98GHH&6=@&-$#<"0"B0CF/6$*=93-1*0H/59,(17:<BG!&54'@-=&BCCD$1,7;0$:/$FD,H!A$%4>2%?H0@7-B+D.3-/5245(F0<,.A)5;+7!:09@D=3A.82#&?H
@r230
CGGGTCAGCGACTGTTCAACGAATGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATNTGGCCGCNTCCAGACTCAAATCAACAACCAGATCGCCTACCGGTTCAGCCATACC
+
6=F3G((".+-B40(?$9'3%#E2>(!!;*CD!7?4%-G/8(D<.B;-3/94$:C>D&-AB-E9*)<HBF?(-9,%3#2(0)0:G410@>,70-8=E552709>*,;#.65)/1"1<AAD=9D8C)2378+@"+*@8)+;!/!>:D'!"(&1
@r231
TGAAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCT
+
=,.!0(A2'G.33:,%778+H&?AF"9:E7$=%/417E,44$>$>E))G+F$)2.)%24,9&%
@r232
TTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTNTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACNTATC
+
?*'@#0+D/68>:B"F8FF%B::D,+4;-7?DAC.2/3)<.>%4#E"%#)F%>40+E=>C.#/0D@:H,@"=E@?&%)4<:3D>@:F&>+A3%H'))!7/EB2"*>#B+4F-'2(@
@r233
TCNGGGNANGNGTNTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCNTTCAAATCCATGTGGGATG
+
))!)#(!'**&!%+#*$"'$*%"*'+"%*!!+$$"!&!'*$%"$*'!*''&*$#()%**("!$'+)+*!$!!)(!!()))$''!'("&$(!!"#(%((##&#%(!"
@r234
TGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGC
+
2D.9#/F6-6;>;CG;C/2/(0#'<318&4>22H@$#'8#G#;2/=*=:G1398DA)F/7;#+H4&
@r235
NTGCGCCAGCCGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATTTCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGA
+
"C3+F6B6!:/E/GE<FA/0C'ED30#!/5%.G&587"A3/6=%;8,(>'&%%E<'?4-B$GH0:2--;HE<B";=215-4+:93*B6;6)/4;H3"*8#"*<1-B:!F5$H0"(94>/+2:GAECC76@8(96F,C$=9->B
@r236
TGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGC
+
3@>AG9%02+>,:17E@F=C5>DD'$%B@%'4$!(@@/69%5&*+<=4B<+88<.>.8$-=&@;1+5$01*!9276!2(H+F?0&#5&
@r237
ATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTT
+
HG+2$+C613B%=4>.:;B61293>+2(&#4!$3FC-BC-87@F./(.:D00FE+B)4(/B
@r238
ATTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGGTGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCANCANCACCAACCGCGCTCAGGGGAACAAACAATACCCANATTCCGAACACCGCTTTT
+
706%5CA1H""11D)%2:3AF7H6/#G"$C'*1C>+$/3?6<"E(DHG%%6.!/!G)G'")$;G!=A*:;(2(G-44/G*!<1!C'F=>3$#!8%+B*1"=<%FH)=F-+0E.F93$<G*4?&'3())0,%/%C323%@7/3,A@5(:*7*F?#/=-#AG
@r239
GGNATTTTCCCTCGNTTNGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCTCCTTGNTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGTACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGG
+
'*#++&"$#+(('(#)"++%'+*&"(''#))(!**&#+()'*'##))"%"!**#!+('#%"#""+))+$'('**''$###%""*'&&"'*!++)+!"*')%#"')(+"'$(%"$(#&#*&*+#))""+%%+"$)'#'!+$+%(!)!(*%!$##(+&++&*((
@r240
ATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAA
+
1CE6E;/F#7-*6C:A=@$(*5+054F-2)*D@E>4-.>E'1:B;:**??6-CD8%3'$!!F,.''&(D>:6B@<3;?)<@F>%$*B,:;1FF$(.*57#&D$%<"CE*'+4::>#''E*=?
@r241
GCCCTGNTNNNGNGCAAGNNTGANNCNTNNATCCTGNCCGGNNAAGAGANANTNGNNGGGTANCCNNGA
+
""$$!"$$""!$""!""""""$$""$$""!$$!!#$!"!#!#$$!"!!#$$#$""#!####!#!#!!$#
@r242
AACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTNGATTTCAACCTATCATAGGACGTTTCTA
+
..5708'=1D7H%@@8:?-+-G0:A=C(F:)3'9=@.==A@4%2>1&G,%#!6;F%*.1>GC-C%0/>>&1:)7!D2@CG,+CD1:88>6;*
@r243
CAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATNCATCAACTGNACCTGATATTGAGTGGC
+
.AH*ABA#&710&+)5%39&$8FF'*=#&G2E4*C!E+(F++2$<.47DH6B5!*=-4H/E7FEH;)&.&3ABDC.<AF)4;?'.2'!4:;$!+.%105-$;$,(E)1"%H-"&<BC2.$>,"-8("+%*-><:D%(:!5@'H9B(<E6=7
@r244
GTACCTGATACCAGCCGTCGCTCAGTTTCTGACCAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCC
+
++"$#+$)#&%*+)'#**"()"+%%+!'$"'+)"!$*&)+*$"*($'#)+$$(*&$&"$"(#'"&!"*))("(#(#!+)
@r245
NGAAGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATNGNTGTGAAACAGTGCTACCCGAACACGGCCCTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATGCAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTNTNGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGT
+
$))+&+#"%"!)%$#$"%'#$+&(%"'+''()")''&#++'+"&!)'+%)#%!(&+"+#"##"%%)!+"!%%'(%&+'&(#*&"$'*%$(**%&"%%')!#&&)#$'"$"%'$$""!&$#%*$++"$%#&$%%"(*%$+*)+#"(!")&'+'#+&#+(!%++*'+!)"+!#+""&()'*(*'(""%+!&'%(+!+)!$+"))$(+&+&(()+*#)*('!(**"+"#&"%&#!#$*$*$!!!"$(($#$#%)''('%+&%*+#'#(#$!'#"#!'%%"'#((&'&!+""**!!$#(#$(+**+!%"+()$#$%$)#$#*$#!**&*#$+%%%&"+)()'!&$$+''*&'))"#!%$'#$+&"!+*%&%!*+%'(*!#(!+%*#)#*&$$!+"*!'$&&#&'"$*&")'#$)&'%#+)##"'&
@r246
CCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAG
+
>;41"D6A<;%F'A8F2";(0%CB35$==!!5=&#?(1.)/+'D+2&?:?
@r247
TTCTCCCTGCAGCCAGTCTTCCGGCGACNTACGGAAATAGCCTCAGGCTCACCGGAGATANTCACGCAGGGGAAATATTTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCCGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGNTTGTTAATGGAAAGGAAGCCGCCANAGTTGCCGACG
+
%?2(H)!E*HD&*>E?F#-()(+)D*%7("6(A6@$$>8;9<-+$2@D7H?!.;F19"!.5.1#1/!A+2$8D!<D0:60HDD(:F.;>H'.E/',=A<76')/?067HG*GC>&5-#H%1+B?!8A&A0-<')E$HF#%33A"4'">3$:!DC/1.12*D"*3AB*G9$;FD>*5!FF'(!<:+@A<G"38G#'&G??(.%#A@)'><#1920:20A9!('H.C3?
@r248
NATANATNACCCNCGNGNNGGNCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCA
+
#(#)'))"*&(!!'$#%!&'!!&#%+"%+((&$''&+$###!*$%!+$'+*$&"!'*)*&)(*#%$"+%!%#*")&'"#'%
@r249
NGGANNCACCGNNCATNTTGNTGAGNNNNANNNGANNCTNTGTGN
+
"#$"!#""$"!!$$#"$"$#!$###!""#$$""##"##""#"#!"
@r250
AGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAGAACCGGTACAGAACTGCACCAT
+
5&H4)B>?+/,32?*2D;8/.C4:=<$9;ED8"BD7)(BA-3*5<"2G3/E6+F$($D,+
@r251
AAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATANTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGNTTAGTTAG
+
6$C8"50->D,B=F!&"&427@<.;B.%>/'F-%53;B-H.-H;>%4H:H"=@?%<E(/'<!9E>'582C"35573C(!*4;FG"&:0"3+43@)B3C&"*.<<2:G6"5!;<0A-802H)!4/C?3B&(<6'*AF/4.$D=7,42=@4FD?$=(,:$),8A)+@0!
@r252
TTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGACCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACTGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGNTCGCATCGGTGCTGTTAACAAGT
+
,H4);G-B,+$*0;DE7H/=.8F3'<14F#5@6&6".;(><50'=&**'.06H2&.2)+)+0245A947F?753:<3A1;E/=0?4#FC/#5A9>&;BC7*@:33-F0?+'*A&0*'+9C==F%;=85H()<:A-&33<A"0"2.C=9%.D,;E&G>D9E+31,?*G+,3+F36#)&4*'*4DH'$@$1,*.(=F4#/44$8AB2=94??2@8GE,E/%6/@>6$CC
@r253
TACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCNGGGAAACGTGATCCTGACGTTCACGCTTACGT
+
)H94H&/=,%@G>%.72ABF.=FE:3$"-2$+@B%>7)'318,-("!"59#7?0-8?:2/,$60GH""-@<@;7E"G=#4>'A-3;3DAGC:43F;&B"#.>=@E6/0FCCC1!?/A</1416<.3=:C#:,9"$/=>+)+$-4:"2$2$#!E:!EFB-G'6'2")3(-$#(C5&1(5!G62,96(,!+.$%'84C,FEA%9"8,H6"$$%=(39&(-?&&<#>7FF;/(AH!BA6!5HC(8
@r254
CCTTCGATACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGNCCCTTGAAATTGCTAT
+
B6/H'+!(?11/!+=50<#!/*/HD258#F;8H,B/2>/4.$52/#)F4@#?&:%(D*>5=/)C')E#$*90>7'7G9"D*AABFC2C#5,G$9>=>B',3@=&
@r255
NNCGGAGTCTCTNGNANNTTCNAGCTCNNGTGCGTAGGCNTGNGCACNCGTAAG
+
")$$%'('#)))!&&)&#!'&()(*(%"#%(*'()#)*)('%!))*&+)#!(!*
@r256
AGNCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCAGTCGCATCCNTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTANCCTCCGTCAGCTCNACTTTTTCCAGNAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTT
+
$$!'(*+&&#&"&"&)#&%$)!%*(""!++#&''*()%%(%*$*%%&!%(%#"(#!**%!$!#&""&#')&&"$"'&'+%#!#!$*$%%*+""+(()!*)++$(#+!#("!*&#+)%%"+'!%$$%#""&!'(!'&""!*+#&'!*$%%##%+'"+*(**('#)')(!)$&$!)#)!"(('!#)*(&!&'"%)+#&'""%'")!&*)%'(!%'+*#&(&!)"'%')++$'%*%!"&(&"%&"$$$"#$"+""+*)##)%%)+%)&(*$(+''""&+'$*!#+*%+%*&*
@r257
TAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTAACGTCCGCCTGCGCCGCGCTGGCGTTCTCGCCCTCCG
+
H,'+GE!A!-')1!<#74(7<4,/==BE%E=%C-9"&4><72,66'72&&#-,)E!=H6HG,&4.4,'CB--?(#3<E*C$E6)
@r258
GGCGTGGATTCTGGTGCCTGGGCGGTAAAGCGGCAAAANACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGTTGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTANTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTNCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTTTGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCACATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAAGGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACA
+
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
@r259
GAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCNTCAGAGGCCGCCACTTCAGCACGAGATGC
+
8(D>,;%$9'*0<22>.;#G:C+>3/<:C+$+)D:F!$1744:GH+7CB/62'/;/=!9+-!=,(1)=8@;.:;?E7,5,!/FH/&&'=,*@8=8
@r260
ATGGTGTCNGCGGAGCAGATTGCGTATGGTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACA
+
#*&)#'&)$&)+*(+&+$*%%%''&+$*()#"$)"&*!*%)'(+"(()*##+!('$%#+!&)!*('(!#$'+%%+'"%%%!**%)"*)+'+&%$!(")*'&&'!$)$!'$#!&'"*'!%)(*"&&#++##$'(
@r261
NTATCAGGTGCAGTTNATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTT
+
'BF6+2+#-<"$*#<9%>GEE%"3$()G*:F%5*(#"A'1=+%C-C<A;1HC%6B)?*$EE#AC*"FC9;A4#4=6,/19;6,:54.99?4?&E"?CH,)>=D*2E""A@6("</<>/D'C4*&5D<6:AE.%DBDF-E0<:8C.=D;/?7;3
@r262
TTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCG
+
93>#,2!;H>?D=1EC956./-!25)<;>:!6FF?!FCC<7
@r263
CAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCA
+
,9A,?5H>4*F29"6F>8ED2$2>72HC"G-9C8+3#:B?90/.E"G=@82
@r264
AGCCTTCTTTNGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAANGCGCCCGCNCTTCATCGTTAACAAAATAATCATCCTTG
+
<B1=)51/HB>H@#.--<8'$9DE&2'%H%@B-876ADA(B,)F;'H@CEC-2AH"&>&(!=!<<E(;/-@C4>G@/<4'CA3@296:CF@"!!86;
@r265
AACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACNCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTG
+
8'24@EH?;!#A)<<@#5D8A<@3''@5)>C"%'<:=D$?/,97F1GAB(!@6;#5!-76*.9)0B+753=5,#/,/&5+<016%&,G:7B(%%",?=+=$*E#
@r266
CATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGAT
+
B04?C1305@8(50G%7%-&DH*#'/#@2":(80#:F6;A+;BH=@A#&>-01@>B)?<,..6(1D/@AE
@r267
GACGATGAACAGACGNTGCTGCGTGTGGATGAGNCCATCAAT
+
?&B'E>=&A#E02<BE5E3HH8:!#/G0"#D-<*!/6%)D5;
@r268
NAAAATTGGCGANCGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGC
+
!+'#$$(#*!&(#)"'#$+'*#+$&#&$(+"*'!$(+#)!%(#$$"#(#"
@r269
TAAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACNTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTG
+
#!**+!*')+!*%"$#$(%'%+!&*)!+!($"*()'#*""$)$+#*##*+*+%(+*%*%'!(!+++&(###$'$'$++&)'#((+$*#("+))+*%!#*)"((%")$#+$($*'(')$#&!*(%
@r270
CGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTT
+
G--(-)H9),;/)+E@*A57AC,@.E0/E:>(4%F7F=.+42*?G$",=A&15H19D'D8-!/GH;:?
@r271
CTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACG
+
F@'G"-84##+?/")'-5=/5,4;!(7!,$C>B!&),%=9F&4@/9@/;('"/5<3;G8C9231+?6<D&8
@r272
GCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCATATGAAGGCTCCGGCAGTGGCGACTGGCG
+
E4B"D>%!#%?=#A;BC2B#H!!3+&D=>(?B0EF"'B>;;H:)*&4(+7%65)0D#.=(>C74#.",>BHF042,*-A=B?1FA/5>4-@='C4492$687
@r273
AAAAGATATTACTATACCTTTGATAATTCATTACCATTTACTGAGAGCATTCAGAAC
+
G*:H4/B:;?A006'!@?!/<$>'="G>)-3;219#C9.3?!-&E!:!&H7.>4F/,
@r274
GCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCNCACCACGGTTAATTCTCGCAGTCNTATGGACAAGCTCATCTGCGGCCTTACGGCGTAATNCCGCATCAGT
+
F:%@<B720'..#CA*:!!D5H%1B")A3C*11;!&/9!D,$@G59.#%)9-);;$*:<$7!@$E1'460;@B?#H+B8=%@8.(;'5=F.36-EG))&H5$8D0B<(6;<
@r275
AAGCATTGACTACTNTGTTAATCTCAGTAAATTAAGCGATGGTTTTAAACATAACCTTCTNAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCNGACATTGAAAATGAAAGCGTCNTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTT
+
DDF@C>?:8.-)7"4FA-%:)100HH3-+A@BH1&E,"%A8D14(7?F==<F+89'F9:88C2/43+(:("6(C19!>;7BH<*+2@!$B>.,'2)?5@'=A.+(#8G/7-C<7?,2-5&E(,##)+:88<)*4+44;4'$,-80:"2FA%.G6E/1,E@B;-:0C8>-?C,(5FF:E'C(=$:&4%2C':-+E.G:
@r276
AATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCA
+
56+?3-3G)0D>/&2D-A'=:&$0E8="8-8E2*,*,+=8#?==-<:G<:;*.>5%E$,689550-28'E!$BH974'(EE7>=2A@HGG<DE+/@5F&)H.C/,79'3B*93/17(A+8-(
@r277
TGGCGATCTGCANGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGG
+
G.-A9B6!4"#/@/F,;A)D.0A@?&.&?!AAG?,=771;'$/"A0'#D'>8&:>$%7+<(?)?F$&DF"-6B"G22F-=;6"75+
@r278
GCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAG
+
HG%HF>-G"57,0/?<F"A*923#",974*GC55B=FE:+)4&AF?2
@r279
CAATGNNGNTGAGCGAAAACGCACGTTTACCATGATGATTCGGGGAGNTGTGGCCATGCACGCCTTTAACGGTGAACTG
+
*)!*&!$#"+&&!*"!%"#$%!"'$$"+%*")$+#"("'%'*&'!&))!"(#&!*%)+'!(!(%$)&+)*%"(%&'#'(
@r280
CTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTG
+
H)E,;8G+E:690#!:D43#%3(9$!HF!&@?;4';A4.8B688B
@r281
GGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTA
+
C!+>9,A*A=!+D#F"+?-G=5$#6C&?-5/:4:29C2)B%=B1/:
@r282
NTACNGNGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCACAGCTTAGACCAAAACAG
+
&(($!'+&")#""&")*$)"#!)&!#"&#(+%&')$)#+%+&$)"*'!+!#*'*$'(%'(+'%)"*$")++*$)''&!")&+$)!#!+($"")%*+#*#%!!%!)&'*#((&!!)$'!!+*)'&)#"%"+)*#'+$'(!(&)'#(+$"'!!%%($#(#(*!)*+$%&%#!#)$($&(!$!!$"++##(#'**))*&'+)&+%"'
@r283
GGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAAAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATC
+
'DA,30%'*"7C2!)B*&!/$.@'-:41./.?.*3H!A>C522DH$,5GG<,%+G+@.3!@E@29&AB1>DGHB$:@#0-?D(A53;$&!!24D5D"<7!7*BCA3,;$C,=CB<,72H2/?B1D@9+9$G+&6GGA1,4.,,!!@&0#$&<B?#?;G%&0D;7*(8E<'/@7
@r284
AGNNAGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCGGGCGTGGATGCCCGGAGAGCAGGGGC
+
&*(!"+*)*+)**#+"!#)''#&#+&**'##+'+!!%%&(#'(+'*)*!)"("%!)!'&)!((')'*(*##%(%%#)'+#%$*
@r285
NTGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTT
+
-&F(H>"EG+/,=)E;88;=C'@:>&<'>15?(=&%:H:"$2-0&$A/&*9C-<!+30HFH3?(,E4$-GB.'%?#1/0%/.H(<*;6@<8'66E95;&*G"&/:!C!)62$&
@r286
CAATAAATGCTGAAATNAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATG
+
F<A*41$#=#<GH=1CAB-)=5.0=9.(*.9-76C;2G)7&BB8A1>/;67.2,5G&>*>%C-,$)@9"BE05&8-E6D1#BG)2%;",427-&0E(0C8/".'EC*6B0!*7>)@<,?G?8=5(E$6$5-@>$(:/C8G7:;7
@r287
TGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCT
+
):F&&<)(4-D=&H+#430162,;=0,&H$4#2?=AE;D(1ECF02?4B<!=#"29
@r288
NANCTTNNCGGCNGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGAC
+
!)$*&*%#)+!$*)(#%$''+'&$!&'#(+!"+&&$#%*((#$(')#$%%+
@r289
TGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGNAATACATCAAACGCCGCGACCNGGAGAACG
+
8-'<A!;#5+<H"B80H##?;0@),<-$'*,(A..%.9",*8/5-'C%1.6$:45C3-+:?80;'%2D
@r290
GTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCA
+
GBG=HA936?-GBG>B<29E4>)#C*)"%.F./CGC&;4!4,.-2;&1.D4>>B.&2>=C0';@C)F*H#GE;&
@r291
NNAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGACGGTTTA
+
!-78"!'0!DD1-#B+,C66!)3H;)?#G*<@%!:87%8#,HAA=B'=;C3@(
@r292
ACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTC
+
D=<:E=36AG@2)(;*%/#345'9><>>6FGC@-=2>6)E455%)FG><%G
@r293
CATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGANAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGAT
+
29/G<AH@;3BB-(E1?*>4E>/<5HCAA)5C**6!$?D.23G(D2(*5=C'/5(+8;D(-F1?'2-8=@5:EFF9!B'47<*%<4(0"0C469*=30'.(A+/485?=8/2G#13+,E'*A39'1-+*#!>*-9)%+8-E-$2&3/<7:3'!;3/!<2116)G*7DA6=G27B+!?7*</#B$(:E;C,&F'7A.=!F4""FAH!38<$F?>H49G*&>D(/C@)BE0H''>!>"A2$@,+B#*/69(
@r294
TTTTTTCAGGTCAGACACGGANGTGGCCGTAAACTCCACCCTT
+
A.H!:@4.D!(<?.B@)3<:&#(<!0-$%A@FB)0;"A*'("2
@r295
CGGTNGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAA
+
F>@)CE4'4;#A2F"/H:B!66(#!G'/D?,%G,FDAC"=HF;.<2H*C0C!22"E)/"F%.:3#?#;@B
@r296
GATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTG
+
G9/CG$&!9"6%@*/+-=97'B=-"C;#:0D4DC-4&(=0#D35>%*H'#3D"*5=$906E-;',19&$F&2&:-G!
@r297
CTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCC
+
>6'-5*(/:5G3@$G$1-(*?"5*+&F0C'6D8"=4'(E%@;#"0%+>8".B?=%@1>21@%E3;4>)#:157
@r298
CTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCGATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGG
+
<5<:4C4&7'39*;$C=E'D@2$EGF:%G/B;4C6)451(*''4AB06#F!AH%G@.D7$$65!</F'>7&(%/=#2E3&4H7GG#"@"*)3<+'C40%/BG1#$4%6<DD()+&>,!2D35FD3&4@=9G(",A$6B*?8*-"'"/1A1.3HG*/=>H)%'6G8D$-/6=E*B+00/9?7!C&3A3"'1;0/<?5+B68)'>?""@D3(;,1808?#EDD52.@C-6*E:6-75:.AF1$C&,G&40:>8)6H%"F@4&06"!6$7G2'%31$G55!(@0H2!5'G=DG4$
@r299
CACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAANAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGAC
+
24&)'"F;5.#!;06!*D74/4=B9C5&A%.B1ED&;"GC41&F"5+0:=C"4(#"&=,"/G.<@8AB(395>D:):E*)7=,)HE'3'"=D<GD2EDB
@r300
CTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGNCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGC
+
*A*=3G$FD6;(.G$4,#50$0H>%F?6C'9GF12A.*:C-;!+/=40-F:.G(27.%4,G21)"$H:;H8=<11?<$4@?B=0>67H/,6'4FF446#?'2CH6=4E@:@EC2?/@E6G?8'(D)6B
@r301
ATAAAACTCTCCATTTTGATAGGTNGAATGCTAGATGCNGATATATATTAGAGGTGATAAAATTAGCTGCNTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGNAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCNGCAGANACGTCGNATGCAGG
+
1(;3?A3/&H58@1A'8/-3.:D:<8.4!F&A/3;#(-18$*!DE-B(";(98(51,=.?1#9$5#2/G%#$-6+5:+F+H0?D2GF23;B%,,#+*11>14(65/7BG3+,(25H2/<&*54>#F:,71%!,(%FB>3GG&&!/1#22=1F8,3'%?B<C6A/'3>1>HG.,'#./G#2H=@$*;C2?4;%7%FE)59*B>)7+!G.>('%5="2(#"5+8,=>%3H8"!:HD;4<H0G4&%-,!0!'E8;F@?.F7%(1+FC9:D
@r302
CCTTTGCTGATGCCGCTTCTGCGCCGGANGACGCTTCCTGAGCTGACGATGCNGCCTGTCCGGCGGACGTGCTGG
+
D'7:>D@@0H%%=><-3"#(32:<1-'!):D;C;<#B-2?38$9:D59A4:8#/8?-,H$CG)6&G;'.@-28B4
@r303
GGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCANATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCCATACAGTTCCCGCGAAGNTGGTCTTCAGCCGTCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGGTTCCCGTTCTGCCTGCCGGTCAGT
+
53C;",-(C#D22B/FC:0*%5<<GCF+%>$*&<:6C*D63/.&):$=4F@?BE%B0&;(#D4>=@$,D8(-""2:9,*;AD'E080F),$,,46+609)$/$>%*">4#(-F)55//%/8;HE?3=("7(+)@*$2A4$)'G&D:@*$H"*$F78$4%3/G&:'")"B"*7B=G9=:A>2,F6"=D;$G9$AD#!>"#G79:8',C5*-'"GB%D%#BB.8H<%@"!:%$E@&D@@#A=G&C'?<*:!$@3#H),*<E+H><.A>6/&:)+H=+H<.>8$4/D$#A,*!=DH,5:,G
@r304
TTGAGAAGGAAGATATCCTCGCATGGTGGAANCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAACCAANGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGNGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTACGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAANGATT
+
+-"9B:/<!8?@1(E;&1@6A:63.#?=;;@5"8-A+>B!:,&E<@G#3%/+7>(=;<.FH8!.&7,:39&4)C(E2@,A=CCF,71$#(3DE60(*-83+"502%F)!A=7A;)D=G#C)GF#>?*9AH:51#'H0B67H*3$(85%E-$&F=)B:61%H:B,//=$1.@+-0&>"9C""9):+'@<(=?A/;A'<A*;%+%#7?:<C0.8E:?+58B/559+)>8:%8@=D/2(>,9&/@/%2+E7)<58A5+#6-G509A-2B5((5B$D,,;)B)H-=059H0D5<;AB)>99.)FG=#EH!+H@?
@r305
CTCTCCATTTTGATAGGTTGCATGNTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTT
+
C&<3G=:8@:22#*8,GE<*8A4<D3B;5&&24-@E@'(>;EE.3%!B"E)H>>F7#-#./(E-.8
@r306
GTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCA
+
'((+'"*)("#))!*!!*()!$$))%#!*#$""&$#$##$(#%+)#$"#!+()#!(+%"((&*'"))++)##!+
@r307
CTAGTGCATTTCATCCTTTTACTCCTCCTAAAGCACAACCTGACCCAGCAAAAGGTTCACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCA
+
$++'##%%+$"%*+&#&'#(&)"*'*'"$(!("%))&'")!"*'"'%(&!*+$)$!#"&%'(&&$#!$+#'&"(&))+)&(&"!)%$)&&"%"!"#
@r308
TCATCATATTCTANATCCCTCTGAAAAAATCTTCCGAGTTTGCT
+
(39;A>27HA1/5H/#@70C$<*AB5(F%G<1)/,*-45G!-/?
@r309
TGAAGGATTATTCCCTGGTGGTTGCCTGATCACCATAACTGCTAANCATTCAAACTAT
+
#?/813H+F+>$7A(,8C'6!$GE7D#*?5C24@3$;%52B(8#$B//<+DG7$:A@%
@r310
TAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGNGAAAGCAGTGTGG
+
<.<13/&E6@*9)(71&?9@<B6C'E:9@.4,$)4>5#3;"5>=F0A"
@r311
NACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAA
+
&4D=)B,4BE?=HF=3,.,-!G'--&*$C'(:8H-45(AH?FF1A7#&>#6%>G<C2F3D%D$'!5<B0=+38H"$9&$FC)B(B)16"?%#348F0C1$-=!90F-*A69A69&2.C#
@r312
NGAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTA
+
%$%+*('$)'#$""+%#*)!&''!##!!++%*%!$+(&"!#)"+($***+('+&!()*('"&+#%+&'
@r313
NNCCACGTGGATTGGCATCAGAGCTGATGAACCGANGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTNCTGAACTGCCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAANCAACAACCATT
+
"$A4&6<+',*"17!=%H:'-9$!/FB-CF,DD7H7C:(B-C"H83&2+C,-%+<:755@8%?B&.4E*FC*?D32-3;<E2C)=&.1&>F3G)&;-+:4+:53,.0,'0&@/0+*A//E67/4#"(=.
@r314
CGTAAACATGGCGCTGTACGTNTCGCCGATTGTTTGCGGTGAGGTTATCCGTTCCCG
+
%:#'9)11432@DDFG$,-?=<.3#41&97GD("G9G8G/@:E1-@87.>C3(<4&4
@r315
CGTACNNNNTCNGTGGCGNCGNCATTGCCANGGGTAAAGTTGTGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAAT
+
)%()&("%&*(&!&#%$)')#%$+%*"$%%##$!("&#*()'%(%$##!*&%)'+('$($"$*'%%"##&&(+()*")"$%#*$+$&"#%(()'$!&+'!#""&&
@r316
NGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCANCCAAAATTTGTGGC
+
%+*)')+)((%*#(!++#("($("(%"%$(&'*&$#"$$$$'+(#%)(+%&%!')*)"!(&*!*$%*$%"('$!'(&+'%!$++"#))!*"
@r317
GCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCNCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGGATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAGGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTC
+
-+,6E2(.-$D<(F(8$!)4,=F1%!><!@%C<25FC'>C>/=@AGEC5#33*,#0@B;H3'=A:*GB3-!.#'A!%12)$F<G:?C&842&#B1#E,=;-*4*C=&+E<7A33&CH!41BF'9.?.:A?-7<=8$*09!$08H;D*AA90/=:!-H54A=?6$F9)+DE.<B9*A3/=.E6+AF?/<$/CC)8%()&DG60G)H15H/CC,-95.56%$F
@r318
CNGGAAANTNNACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGC
+
%$&#"&"($!'&+!$("+%#$)%"&**("'(%!''%%((##)&(#%))'+++*)*$"+*#*&&(
@r319
ACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCG
+
B>"!D"$@$)9(3%:%!%$)FE=C,"1!C+BA=97##F3D;:%@='
@r320
CGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGG
+
<"D;0?=1=.D>%%)9?!:1B02,0E-&*7A4#E8D8<?<E3@5"4;',('&G2F-D+$33H)%
@r321
AAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTT
+
!=E'%*+AB1A<-8F;350:?%$=991C@1:HD*214*+H5.')@6
@r322
ACCGGGGACGCTGNATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGNGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCA
+
C%//HD!)9F4&=5+D46>0*3C$&4D,AA#,8F%=):;)6#AG4(G#1,=?!979*#,+2EACH#2:.<F2+>B'>G+H<)(,*D>!B@;-H6(@+/E87-)*4E!H8;53>AA@:;00)(92:@C/5D6%4)'.9D.=,%'='7./@%($73'D32,0%264?B=6,6FH1D*E588"!$FG5D,*1,7%GAA<35#
@r323
GNCGNNTCGGNTGANTTATANCGAAGNGGCGCACAAGGNTTACGAAAGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTNCAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCT
+
"(('""*)'(!($*$$((%(!#)#((#'%&&#%$*''(%++)+&$+$&'*($"#*&++('!$!!)+"#!!+%**""(&*+)"(")!"#%$&&'($(&+)"**%"!%'''(')")'#!##"$"+(&(!!$(%"!$++#')#&&$&''%")&'%(!$%")#!$$#%%)!"$''&'(*"&'%$
@r324
CGTTGAGGTGAACTGGCTTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGNAGATA
+
+*%'#!&%#)")%(+%('*&'**+)#+&*"$*)#&((!%%#!+$&*)('"%+*'!++!%$#''+(
@r325
CTGTCCAGATGTGAANGGTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCNGATCCCGGTCTTTTCGCAGATATAACGGGCANCAGTAA
+
G3GC35G650>+(6E@8>@@F!$%<(*1,+==B/,E$A=$D5<,?;9).;).3'/&#B01!2=C2D6&@G<.8;G=5&,1.08,B&/(5?558@3F%<0637?<E8>@BF%572D=3*#A-G,
@r326
GNTNNAANCGNCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTA
+
*(%!"*(!#"!*+"$%'))*#*"'("$#%*"#(()+%'!%*''"(&#)%"'##*$&
@r327
NTTGCTGCATTNATCCTTCGTGATATCGGACGTTGGCTGGTCATATNCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGNTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTTCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCAC
+
"C$D)7@H&F.?:));@>4-(:&:.23"A%7<&818@,5HD.13&-&9*1@0,$2-+$0"$;7"!88E@9DA7=F1'1*@!H.&5)'%@+<=9-@EH0#$4(EE@(802%"GF-<."B/E3%1,97CF!).9G'$!3=<D"&9="@$CD,2/&FF4-54-/?'81<:@<>F:8)D7!-.E#G':FHC2'C-;B.4!?7BG;-!$*
@r328
ACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCNGTCTTCACGGACTTCGTTGCTTTCCAGTTTA
+
=@A'"F=1&&)*9;)(@+%9:F/A&=/4+$;3(/A%.?6(%51C<H?HD**.G#6H)>@)(*G$:#H(G?=,8D9
@r329
TGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGNAACGAGGG
+
2%"8;:5#?#5=E2%#))H84FC8-(62"%6B#!8:H!+,!-6,-1!
@r330
NNAANNNNGGGNTGGAGCCTTCAACGCGCACGCCCTGTCCG
+
"!%"!#'$)&(%'*'+!("%'##+$!##*+%"$#&*(!#")
@r331
TGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAA
+
2,6&E2BB.=@)3.?)**?:5CA>@!&%!)#7=1&9':>4G0-=)1;E
@r332
TACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGAGACTCATAAATTA
+
;,0E3>#&HDD)'D?D#5,B@=<+G&&<*1#0:";3%8DH:$)'H148'@:-@71"E19ED?"47/7EH,;69
@r333
GGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACNGGGCA
+
>952;7>(6C<AB+#<1)BH<(:H(H7+*H*,A)6%'<0'4=&6>&;=
@r334
NTGTAGNGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATT
+
!+"!)''*'$$"(**('*+*#%#(#))(+(!)$*+(+&!"!"%*(++($&!
@r335
GTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTNACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACA
+
BC%==).3!@G&6).75CD?#72<<?/4%&)D>$8$#.B2<(#:@#$(=&2.$>2A/9&G$&E1%=8!?.9.9-=6F+6D8+5()A:8##
@r336
GTANGGNTNAAANGANNNNTNANNTGNCNNNNCACNNGNTNNAN
+
#"#"!$!$!$$$$#!"$##!!#"!$$#!$##$"#!""$$"#"$#
@r337
NACCCATTCCTCACGCTCCATAANTGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATC
+
-<,7,(91'456?H9&!$E7;1#!06GFC9>0$<(B8A%*<@%B>"65BA,,":AB&-%.8)(D5#G*!+-412-98'C(
@r338
TCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTTTGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGANAGGTTGAAACCNGCACGC
+
+G#8D":E5@%#$+4+9?$1B?C#.'CG09"-3EE!2B7A%1+5!!(-#$>:(9,F9.02HH51,G=*.*A431C4)H'(3F?,/+CE7=8"==@)!(@0>,990@)E*BFH.):A9D#70<F$/:>E,A0125B!908!;A"((78+65)4DC6*5?B,7H%&&.F'8<"(E"2(;E/>-B
@r339
TCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCG
+
<5FAH:D3;!@5$B?/6)=BBDA7'CCH?#@54+:'G)D,54A)A35=1:<1B*/E(",#:=(
@r340
TGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCAAATTGGCAGCTAATCCGGAATCGCACTTACGGCCAA
+
2&)DA!(<19HEE7:"2$;8?)86+HE)F@>DF=(EF'#9?(1B+!7(FH&41'8AB0H@8)F#?%@1.H!*%+B03;419F,3=&6:07G!?:C?(-*"-86%4*0>,G!5/:8:C+9HB?
@r341
AAAATTCGTCGCATCCNGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCANCG
+
92;)7<'A5@'9!36#'16,D7@D&7+.@*288CA4B.6G"9H/2D1,D0@%4B-0D4>;-7
@r342
AAGANATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGT
+
<-9,8A?'%"7@+(<04F-+0+C5$H%=-:E&4=AA8$&%7HG5C0AEB=!8?:F2F8!#6+?
@r343
TNTCANCGTCTNGTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCANGA
+
&!%#%!()"&$#%*%+&&)(*('$&&&+!$))'#&(('+((#!)&)$(!%"%&!!%"*!%#((
@r344
CATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGA
+
.1F3.!.CD%'?>+/$&3B4A@1=;"A@B%"2':$@#*+F$%;,4B-EH26!FD
@r345
GGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGANCAGGCCGTTGAAAACTTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTGNGGGCCAACCGCGTTGCTTCATCCNCGATATCG
+
<!?2#GC$-60$5FG?>E?48>3!E6=F#!.(-79H=0>A)4EG@)<B?.'H&::+A0G9F1):?*D>"=CB6H),8F?-#='$'-/HC:+/&1AC;&CH)'636.)7G+C'?3+C%>=65:7+3#1E8#>A$57/%4G,B:+C+:)%$-A9>'3*'39$#'A75!?(A&&5;=!!C?8-=:3!5+$,2'3!4)B7&()=6>$;=2&#3<)'%53>%8@'0F,E)-.?.'3;D!>4@
@r346
TAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTGAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAA
+
-($+B&:.'5E.E17;F=??,E"@!+5($/"?'7.52*-6(9)F"6&.$:C<%91'&6*AGE4%>-G1#.&D7-;'$:.189)"G"<<CF'CA
@r347
ATTAGTATGCAGNNANANNNNNGCCACGACCGTGACCNGTTCAGAC
+
$*$'(%()%)*$($"')"!$""$#'"++)&%$%$#+*+('%"'))#
@r348
GTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTANCTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGAT
+
B.:%59#7@EDEC/:($>,.0!05FF6G62:"(63")G.=#)3''*)DAH01:5E>BH,@G*?<*C=9'6=8*&$'G9+16"1AF9%A>C6,!"?#94<!C4>-)8C(G)F"?F@A3)"1-3!,>E?H,:++C<).#%:/<=*G*&@!>9;/7;=
@r349
GCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCA
+
&C:+'@750*B/.(&?3*AB/,,.1::;>*#665,(,3D@F@B+58+$D@+3&@<@!BCA,&C3#F'#E?)0E23@-F=488/1
@r350
AAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTT
+
3E6F7'6F$?0E?)**$1B"2D<7/B,74<->:H/'19;32):**(,$'8.;(%?F+F8G+:%<'6B,$<;@=>A(:<>1H
@r351
TCCNCCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCG
+
+)"++*)#(+%"&+%+'"!#%"''&#*$&!*!#%%&)(+''$#!%+'(&')&&!#!+$&$'***(%&&
@r352
TTTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTATTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGACTTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGANAACGATAACACCGTGTTAATAAAAGGACTTANAAA
+
&#+D22>40B/G%:#<<0?(;C+,?9B-5(,F!2>98024!?E#8AH//H#=88*G"69?8D&DG516.'<$@@DH*27'-'A-HACB=(:?)E&F7):?263<>!#&1+2+6C1>>;E1%4E3);;1?*8=,'7A%=D,6>8$'D:E:$2<D.H59#C)=%@,EG*'/"469H!.<$/@$:"D1!<481&?$7;-C$745+36/'>*&+:8>?%:81;)/<666FE>4B2<!&DE3+#"0#?($/%-88/
@r353
CCATCGGCATTGCCTCTGCATCGTTCATTCATATATGNANCCTTGTTTTGCAACT
+
?=F0';:/4#>'(:<#9#82$E2"D!(2HC1/".'65BH+/#>7EG-=FG8H<?*
@r354
TTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGNCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTNCACCACCTGGGTGCAGATTGT
+
*6,-.?351*(2@<.&G>25:#$3-'A<4?=(B=57#";%:A/8*.@1D06=<FE%#3:;>#B;)3:G1@4:=E5BC.7"9BA=2(@!(9%6D:+7D:7-A8!,-4$,EF>?0H"B*B(52A=1=<0'&H60/=<!<?A(F0;08-2CF+E68/E?F>
@r355
TTNAAGNNGNNCCNAACATNANNTANNNGNGTNNNTGNANGNNCNNNTNCNNNGTNNNNNNGTNNCNGNNGCCNNGCNNNTCGGNTNNGNNGNCNNGNNNGNNNA
+
!$##!"!$"!!#"!"$#"#!$!####!!!"#"$!!$"##$"!!"!"!!$!!#$"#"!""!"!"!##!$!#$$!!!$$"#!$#!"$"""$#!"##"!#!"####""
@r356
TTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTGACGCCC
+
5;)9/9+%G);@/=%-9D82%.++*:5'4%G=B"D8'%'F<C,'E2'+@!E3!?A</!#+'&;H"5>$5G4='17@"5/339@3(A?%=.=65/H-@8B<G.#26
@r357
CTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGANTCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCANTATCAACCTGGTGGTGAGCAATGGTTTCAA
+
&(.@$/31/0EC0$A/"#7.*F?0>AB9:A,D%2)<*2(.+6+;)A$%<C1?G->;?GG<1!8H?G0H>$.<1DG4F3@8(&(D!00/3)-C-:@.C&,"'$;:GF=##7<",G29H;9FD/&$D!6/'4!46(&+*'4<,/=C6@ED
@r358
AACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAAT
+
H;0$H>%80@!:H20D2#B8(A<EG1C(9&A"?<H*6$F<A1D**H
@r359
TGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAANACGCTTGANGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCCATTGCCAGGCTTAAATGAGTCGGTNTGAATCCCATCAGCGTTACCG
+
1".HC6&G"C6#3-;;2*<$A,&D?+%3#.@8'.A5>)F)#4+?."<A*&"*&;7&1%!*8<8,86A3#.D8$+.*D.;96A#8<:),%@D%$34!44!->/+G$0@21$B347>3<G!#@@=>/%>:*)%$!2%"AHF*,(.9:>:4H*"1A5)/7D#<HC':3.H<-#6;3G$@%DA29=6)HFH?$:*
@r360
GTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGCATATCTG
+
H?&G@C,&CEA9E83H!3?>G.E8G38<?C!97!2%17:.==CH67</7<HE;61C:G7+*%A<C%:"
@r361
GACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCNCCCGGCGTTTCGTCAGAAACTNA
+
=D&D!(E16+F"!A:44AC<?9&#''7+;-20;)/8'E$BF.8?$93',&<3:7>==5+;4%'):*>=)GBFDA0#
@r362
AACTNCCCAAATATTTCGGTATTTGCTGCCAAATTCAATT
+
%)'!(*+*!&)*"#%#*#*(&$#!'#)$%)($%"$$*$#&
@r363
ATTGTTCNNTTNTTCCTNACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGNCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTCTGTNCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGNTTCAAGCGCAAGACGGGCCTTTTCA
+
$*(*&()!"&#"+!&*"+!(*&$+#"!"$!++**)*!$&*+&+&+'&)"!%'(%)(+%**'%"(&#)!+'+*!$!%!*((!&%++(#&%(##%#')'!$'(&**%'*&*$'**$'"&"+')!&#%#!$+&$*(#'!*"'%&*&'&+)#$&+)$)!%%!#'$)*&)&"!%)"$)!()!%'')!)%&&***+($)
@r364
TAGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGAGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCC
+
("D7.';F62"%-',69"E28('F16>DEAH/F43E:A+@%;#41538:D;C()52=+H;8)),7(&)0F?H.6,(!1D>:=#<<71=0)@-A53DB7*;
@r365
NCNNCACCATAACCCTNAACAACTGAGCAAACGAGAGAGGTACACCGANAAATGGCAGCGACGCACGCACTCCCTCTGGCGTCACCGGCCATGGCGCGCATCTGCCTTTNCGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAAC
+
#'!')'')**!%%+&%"*!%$&$'&+*#&!#!''!!!*%)'!&&'!&$&!&&'(!+'+'&+!%"!(*%*)!$'""*)#+$&"%)&"('%!%&+&!#$*"&("*#""$"*'!'$*$!"$$'*!!!$'$'*$'*#!''$%&&$'*))))$#%"'(#(&+'
@r366
CAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCNTTTCTC
+
<&1E=AE02-5>'=)H8>758,%&""E%,:+F$2FC-826D4D0?%4
@r367
GGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGC
+
BH"1&DE?BB'<=1>#""'+(0'2E:"=DHFA0!3"9#?&%BB&$CD=<=)B=2$B8$'>)AC"B,9:A&B=@E2=E$=10:E)G::$6G5('0=085=7);F(04(4(9.'!')'>0
@r368
ACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAANGCCGCAAANCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCG
+
;6*:)#,7%G2+.16E0A0$A<8:/<*H?F=>?3)!'HG8G+3$"D':H/AA'<%@8F9A@.97<:"(A68*E97=-?16";.E7)=,*(4A:B?*D3.9E@3%CC(C13<-;"FC,
@r369
TNCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCG
+
'"9G#2-G?3?4=3B%8G&<1A#8@9G*HF=;8(8?!DEB;80C(&.1$7>D+!3'B2B851/G."+!%1E1<1/CDDE>"C$2+5E2-+9,?)*1D%&B'94BBA=&):#C7+E-4FF#7,/>
@r370
GTGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACNGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTNATGGTCGCCCCGCTG
+
!<!$E+4+%B=B44<"7;1(<7><;%HG!B+:45C0+EB<3@;?6;+,?@'3%2,1)79%?=6=;62E@F,5H:'D&'$--:;6>(2**DE6>*A+=E=/@5/5E2>0+'-87F'B9=$E6:%@6
@r371
NGAAGGAGNTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGA
+
*)")'&(%!+##$%(&()%)$+")&&!$*!!%!+)+$"&("!!%$*)"#%+'*)#$%+"(#+%++*"!+&('*$(+%+(%"%(#!()#+%#+#&&#+
@r372
NCGGCNGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGCCAACGGAAACAGTTACGNCGATC
+
!@/:1?>H@5::E(>7E7GA47386$0G5$37)&&8@16-:!@5>E.:'%&29G!0EA-/.9)$74)$>54B5>+:?.?>>*?'
@r373
TGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTNT
+
8+:<E?033"/:)4E%9%'-3.@@-,'%--9G)$!;;5/?<02=)',ED9)#'A-A>>.7,1B&G6&(C$C*D!C,D%<D
@r374
AACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGA
+
*")935&3/8:)C+*$4$>86E'A8:%+%><$+0#".GD90
@r375
TACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAA
+
C682,H5)>7%!2=$49(2-;:%*5)*C;F-C,!@75F9+/-?+H7?>B?&1+987/F
@r376
CATCANCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTNAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTATGCG
+
4FF4F7*F)5D4?;$8;=?17+.F=B2-6E85.C1&:.*6/=D$&*"#@2E@(?8):7,ED7-(#?*HF1B;.11B<&G$3#+,?2.(1.++5(<D(46/B/4'A9C9.;1$+H4E2$('<+"AD(;B$1/:=H!4-3@9&:)-%#!8H;;<8(;0<58*H.9>=/"2G<:7H,C+1&AG;#40-$#78541$7?+'%6A=H.;,%8H2<"*E!E(4@16))5!<78'@(;@(-/*2:>/F8+D*!C'3?/@$8;>G5$:5$D"%)2;.16$BB=5%57G&*##C/7?$?!$)+7A1!E6:?.E..H
@r377
TGTCCNCNNCNTACNCGTCGGTCGGTCCTGCACGAACGTCA
+
#(('&")&&%!"'%"#*"&%*)*)+#)(#"!#%''(!#('$
@r378
TAAAACATGGGATGACGACTTATTGCCGNTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTNACACAGG
+
6E7H!??.?7FC@.481AB3'9#1E-/$F7="':<,&4+40"EE5':>/?@&'<,-*H/B&;-%E"8G,%>0&@7&0*B9CB>
@r379
CTTGCCGCTGCCCGTGCGGCACTGCATNACCTGATGACAGGTAAACGGGTG
+
C;(.)1@0(>"4<'.!2;":@5A!0>A+)H9?46/=H2#H8!A,0.AA:(D
@r380
CGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCNGGTGATCCGACNGGTTACANATGCATACACCATAGGTGTGGTTTAATTT
+
-E@B=0!%+03F@3?E=3>:"G)<$.3./!C?-2:41=26AF:&,:(AE./F#C1A*@40*(11=E.-1..$?<+';)"E*;A/*D1A(G=)289(;E(3G!"5E+&F#<111?C37&;,08+#-*.@(CD6E*0",&H?B2C"(2?B=!+E)-D:--/FH1/#(''C5?8+24;(-.(C&8('79"C./&)?1&9,)#'CC?45B)#*#%
@r381
GGGNNAANATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTCAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCG
+
%"#"!&'"(+&!*'!%%)+$##%!)#*'&')&'**$"%&"'""%#"%!%*"&*!'*&#&($#+#("*##'+%#''%"(*!!*#(*(!&)#"+")+&$$'"(')%#&&*#!%"$
@r382
CANNNAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAG
+
'%"'"*+)*&"$$#(%+%$#*!+!+'*%'"!('"##+#%$%&('*&#))*%&&+*
@r383
CNCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATNACT
+
("?D0"C)(H11A09&9F1@C3$B45C#(0%(HC(#',E?AAH)+D8-#
@r384
AGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTNCGAAGGAAAGACCTGATG
+
7,1<F/)E!(D6>(5%/,.+9!;A9!G6>*=9HC(AE&<DBE45/)!8?:*,:,?=B3$<EBD%5$-'F
@r385
CAGTTCAAGGCCGTTGCCGTAACTGCATAAACCATCGGGAGAGCAGGCAGTACGCATACTTTCGTC
+
11B-%@0&@)7B?"/*$1>.6AC>42F,>.(DG6B0B59A6*-B*96-&9D09(++2A+#:%))0G
@r386
CGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCNGCTTCG
+
FD.EG##'':?324C:@G(-F&0AA;D'-?3:4@F'4;)H)<-(8/+*G-&)F'@(ED2B<3B-'%#H"!!9@:-C'3!;/
@r387
CCGGTTTTATGTCACGCACACGGGCGATGAGGTCAGCGCAGTCAAATGCCCCCGCCACCATCCGGCCGGGCGTGT
+
++)*+&($'"&""(&&%#+#"&+!((*"**&%&)&&#%"%#%+)+")%!'&*&!&!#+'(*)(%&%+*#*(+!*#
@r388
NGACNCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTT
+
("(&#*+$)#"''#("!'"#$+&))#!%&'$($&"#&*%&+&()*')##%"%(!&
@r389
AGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCA
+
?D;4':!B3DA"(:$B&DB>4/86:F(7!E.A$E@;D*>B#:'G5F,,/;8
@r390
CTATGTTGACTGATAAGNTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAAC
+
'&"%+"!"!%)#(&))*%&()#!(*"'%+$$&*&%"'$(#"'!*#&(%#+"&&*&
@r391
CAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGT
+
.>-.0=!7&#FC<:9A($5C(#CE?@B;@@?C%'2A+0B6B:6(AEE3,CB2*+.@0@;&A.9(@4:0/F@AA?@/CAA!BD?4
@r392
TAATATGCCATCTCTTCANCTATCTCAGCATTGGTGACCTTG
+
$A1=@21;6ADC5$/75C>@;*D?-%@D=96%@!=G-8236?
@r393
AGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAA
+
@-'.DCBH#(2-!0<F8?$,67#064)<AF>!2',$$/@118=45B6:?E%7$
@r394
AAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCA
+
.'9A:&B73#H>1>+0;/3,:/$?7C:6>/%A'</;G88>'2F/'9>HC&'0=*C/+;<#6@&E)/'.G.*7H&,H/".*H1,9B+GB#03'$E6(+-H
@r395
TTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAG
+
@/#93%577;C8*$4F@%7'1F1!5?G#%==&35</";90-B<9-;?31),7>4?6/8+G"=4!G%1G2H0+864'&E;';-B)6-C8C;<<&#H*/125685G@G7-10(6F7!H2')'D<6F!6D,52'#-?*%1B?:H(A+&4=;1"(C3?3C6+G%(3<%=C&8('-6)%E,G(D6E5C&02E/$'<BH
@r396
TCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTC
+
A>1()(25.A#G;GH*'D-65>@-,;AE&D!!:2.1*1EH*(4*3;<>E(#'#-D?=591.+03H<.CE4;B/@@'48/G
@r397
CATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTNGTGGTGATATAGGACAG
+
.(4"7B,<(48&+;5.#7,F17E.E1)$8-30B1;,D'5)"7H'1G$8>D4#;H>&B<,<+D"
@r398
GGNCGNAGCAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGC
+
'&#('&#&!+)$*&*'($&)&!#$+'*(!##'("**&$'(*''!!!')&&#*
@r399
ACTTCTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCNCCNCTTCAGCGGAGTCTCTGGCATT
+
&'&%+*"!!%%%%'#**'!&!*$*+&!((%+#+)$"#$)&'&#"!#!#*)+$%+"&%+)"(+$+&##'&("&'$(*#%"#&!('
@r400
CTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGAGGGANGCCTTNGGCTGTACCAGCCGGGGGCA
+
@=6E*@-"%HG=&)@2(-/,#7-4<:C%D<9CH1:,+16E.2+.1",$D*2E*B#A+:?F=*-$?>%$E#7)5?BC?3@1?;-@(+.2>+4.7)3C&+08"5
@r401
GGCGTCCTCAGGATGTGATGGAANAATACCAGGACTATCCGTATGACTACGGCTATTGATAAAAATCAAGGGTGTGGACAATTCAAGCGATGCAATCGAGG
+
!0;77!82@B+A+>G9?:<),2H5D(+6<?3DFC71('F,C1C4)*+41#8FB'B6>.D8!62D*C$A5H+C%,<*4$=(3$H(D34?-:0/E;6=0.;/%
@r402
TTTAATGCATCGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCACGTTC
+
6399/)B+@4-0G%%CD+0)9#GF.@!2:*0A!./B/;9,0&:>,%<$,698&:A<C6@3>/0H.&9;?BE4*%73<'5?8F'47$!+67='
@r403
CCNGCTCTCCCGATGGTTTATGCAGNGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCA
+
%&!)+""(*('!*$)'&)#('+)'#&"%*&$)!!%"$))"&+'%'#'%#)!*("+'%'!&%%#'+"'&!$'%#'("%+"#$&$$+"+)+&'$%)#(++&""%#+"
@r404
ANNAGATGCGTGNCNNNTGNGAATTNCANNATTACAACCTTTTTAAGTCCTNTTATTAACACGGTGTTATCNTTTTCTAACACGATGTGAATATTNTCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACCTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAANAATGGCAACGTGAGCCATTGGTAAAACCTTCCATGNGATACGAGGGCGCGGTTTGNATTATCGTTTT
+
$$&*&)*'(#&%"%!"!("$)*#&%#*&('%)+)"%%(&$"+#&(+)'$(+%*!+(%!*!!(((*)$)!')&#$!#$#%!$")"+#'$$#+%)'(%&#"!!#(')$'+"!!*)+%##%+&$()"+)%(&#"#'+*+#+&$#&%'&+(#%*#(&&"$$"&%))((&$**!(%+#+*("$$$*('%$%*!(%$%$(*&)$!%)!&%)$('+%'!$&'$#")#*"!&*#"'&$$**!+*"*&+$***+$('&%)!!%'$&)*$%)''")"
@r405
TATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTNAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGANCAGTCACTGCTGCGGTATATCGCTGCC
+
'<!"A%>.-C;8,?-A%*!%*DD%@47'9FA=5BD?E8HF@C89:B15F4@'A&?D!BE)>45#G2;6<B#3>)"+&23+B1!DG?!E6!>A%#3,B?31@:AD=8%E/BE.5%EG/!>&,!6=H>#-24GC:;B>C2'55>-
@r406
ATCCATGAAAACGTAATGCACGTCTTTACCTNCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGNCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGATTGGCCTATTACCACANAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGAGACGNCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGNTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTNCCCCAAATAAAAAGGCCTGCGATNACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCA
+
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
@r407
TCNCGCCAGCACCTGATATTCCCCGCTGTCNGCAGTGACGGGCGGCGACCTCGCGGGGTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTT
+
*'%*+)'!%$!+!)")")%'+#!+'$%&%#*&&!#"(('+#('&)'%"!*$")'&*""(%&#!&#**++!*!'*&*%!%!!*(%"!%+++!'*+#$&!+$&"!*$"'%#'#%#$*#)*&!'&+"$*
@r408
TTCGTGAGCAATGGGTATATNCAAATTTCGTTTCCGGAACNCCGGGTGCTATCAGTGTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAACTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATNGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGAN
+
$A1,$F:2=(/'EFC";,A?!%'9!H(4@)C&(!+='GHD*9F!=#1#A&,&BF,?)?<6'B<<9".8BE;!54;"))*3-*<1F@*?&02#,;:.0!)GH.?BFD3/F.8H3&0CB8934#):=6B>D?2G=''4#A-2C4(%-*H88%:G@)A90&?;(71(.24%G<&'&D*3CH57#
@r409
GCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGANAACAGTTCTGGCAAAACGAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAA
+
-G2>3G6;HBE?:/,:@D-H$;$'!FHC#"/"3F"((DC42/-::!A(4>?(#>:G))3'?*"/?FC##%&"F>@H7H)6:9$),!#3-/%,D5%FA==):!BAC0%<HDE,0"4DE@.D545.8D?<=C#6G5A40G7CAA2.<%/E)B##BD"?(G*
@r410
NGNNGTCTGCAGNTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTTCCGCTGCTCCTGACTGTTCGCTCCCAGAATAAAATCNATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTG
+
!%!$*'(%%#)$!+"+&$+*'+%(#%"$!'$$%'"'(!&(#&&)+$##+(+#*'+'"&"#!'(&+**$#%$&!"*%$#*$!+*(!'(&*$(&(''$$")(#*!$++#%"$&'+''(%*''"')*+$"*!$%')*(&!%&)''+()#%+$$&*'+&$+'#%#!$$+++(%$$&++'%*%%*(&&"&)'&*()#(%*$""!%')!$'("''*%%"#($&(+#$$*(''!%'&$"$$
@r411
AGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCTTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGA
+
';."(A(10%2(,$:60.4%,G!;G?(75$;0&E."GG!*--/(("2!)%;21BE1H;*.!(@*7.()/-=68#G.H*($'!":43(75$5GC+6FF%F:+.:428G#1$5@
@r412
NGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGNTTCGG
+
!(%#37)6;#G;D:+;)+&B!!&%=#==C/@76&;.HE@?:?17$,AC'-D3(7@D@"2.2?+AD?F#;:4,$-$+)H4>
@r413
NGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTAGGTAACTGCATATGCTGCATTAAAAAATCAACGCAAAAAATCGGA
+
$F9+7-3),BA2C*/2$%2<EDH6$D6$"(D(5!8)$;*$H:+=*=!,0E)8E@;0H%8='4B?3$2#&H%9$<+(#3D?>:87@5D!9
@r414
CAATATGCGGGAGATTCCGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCG
+
E7E5D"CHB(#5%=*'=D/-(43#1!8B0@%(9)@"-70@16%H#+9$,$/#.?4"(?4GGEG>+:
@r415
TAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCC
+
+$&&)!%*#)(+"!$*($%$&($&#!**!$%())"&$"%$%%$'*%%%*!&&&+&
@r416
GCCGCCTTGCTGCTTGATAATATTCATTCTNACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAG
+
',FH(&)+"C#%8!'!<)1!15BB?1+H23C(8"-9;$$GCC:3=0;F3#6A)FG-'9,0F0.0F88-@,/%&13#60>:E$>+H%C-=%C7'>H
@r417
AGACTGCGAGNATTAACCGTGGTGAGGCGATCNCTGAACCAGNAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACANGCTCTGGCGAAGATNGCAGAAANC
+
$+#&$%($"(!%+++("$$''"#$*()*"&"+($*)+&"$%&*$()+"##&&("%*%+&%&&#)(%%'$)!))"#"(#'*&'((+&'*%#*#%%%!&#*+&!'%'+)!+%#"%
@r418
GAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCA
+
'+(#)()#)&)(*%!)++''+(#+(&(!"&''%#('%+$!!''%%")"$%$!'+'+$#
@r419
GTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGNCCTGGCTGAGTGANGCCGACCGGCGGCTGCAG
+
=),6+">?38?G2@.E8H!9"'<*F5E?+%;!<G4G$GE9#;'81B9(?"D:787315:<0#*HD(#;1B:==B".F46'A"C34$.;!7&&D(?45..!)$53>/#H0'":@
@r420
TAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGNAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGNTAAGA
+
,?3(,%/)6:!6G:F;A:*1:.A31$F+56D,$1.8F?8<4:9F"H8-+@,G.17%.!FF:A1,2,7+866??%;H//"1H521:$+/3'CE9$2D5E0+50?C:2EB"H>A:C>?6&G7F:*$#>:60.;<9!;/60C)H%B%H31:($:>.E<?,,49<DB"A"3
@r421
GGTATTCGTNAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATAT
+
(;2C79<;0$-,"#+)A;300HF/5+(!A3>.=392EF00D;$A<$-'7?(*A*E&=5:1%7D0-.$1@G:C/066E1,E>
@r422
CGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCAT
+
)BC6%";)A&G$;G-(0.!8;?"9A;,A/D+$G5822?/G&'"604<!#+$16<:
@r423
CATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTNGTTCCC
+
B!!:645D/@*EE@44/$H,+AC<-1</?;'AAB!9:2&5C0#HC#+F3CDH9)A"
@r424
CNNCNNNGNTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTG
+
*#")*"$*$+$$$)++!"(++&!)$+&#+"#$***("&)$()
@r425
CGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGA
+
CD1<,H$.1><%":'!#?8>$-9$."5"?6(2E97)):>EA%$;#+"#
@r426
GGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGT
+
8+00B5G$-$*;<9D5A$!?7H;<?CD<!*-0C:G6&1>"01B;6;$;"713BC>??<B$0(!8(3H;HD6'#>5'"-E15@+G/$B5)>>.3EA#D(@9?6/2A<3FEG)*6(7!8G.F""FA'48G#"D@$+*8@2B<>)+<+'3!>=.6F+=3)0!:A3,D:9E9@'>>$8>?<2/0)@-?,AB0E('7@H(=+<84.:4GF-E@($!,0'(#$,@"'1?8E!$*3/139#?H;$DB09
@r427
CGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTATGCTGCT
+
G;;7=<E+HH">?A38>(4'D--)&>2'@,4/<,E*F%="-#4'@?(9-:A7#%/6/,%=B>5!&=&?
@r428
GATCTACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATG
+
#($)#%'*!+("#&"'!%#*((#')!(*")&%'*!&#%+#$!"'%("*%)'&))"('#&&'(
@r429
GAGCAGACGTGAGCGTTCCGCACGANATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGC
+
*<$2GA2&&B2E8/)=4$;A+GC@$F+B>:&A!-"4B?%A@C363/C-2(B</&F>'2;E65'-5/,(44?73<:/>3&*&/<8>?<"D,$FC5-4'D(E;;GB3.,(03'""(G
@r430
GGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGCTTTGAATC
+
86E;>3%2HADG86-9G-&6"4?<%'=>;9#B$,H:;9#.FG
@r431
TNNCNCCCTTCACNACCATCGGTGTGTCCCATCGCGCCAGCACCTNATATTCCCCGCTGTCTGCAGT
+
*"$*((+$&"$&"#)+)#"#"*+(&*&"*""#"&+($)%$*#()(#$!&%""#(#&'')"!)"!+'!
@r432
CANAATNAAATCAACGCAAAAAATCGGNCTTGCCTGCAAAGATGAGGNGGGATTGCAGCTTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTA
+
''"!*$+*+*$(*&'"#'")+)(*$*))!!()**+)*('*)#"%+*'(&*#*#&+%!#%)!*)(+'*+!'$)!$("))'$**%&%'*+$!+#"!)++#)$)#'*$"&#!##")"!$+'"*"'&!(*$*&*$+
@r433
TAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTNAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACCTATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCACATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATNCCTGTTCTGGAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGANGANCATTTCGGGCGAGGGAATTACACCACGTGNATTGGCATCAGAGCNGATGAACCGACGCGGCTANAGCCAAAGCCTGGNATCAGATATCNTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATNCCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACNGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTNTCAAGCCCTGTATCAGGACATGGTACGAGCTAAAA
+
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
@r434
TTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAG
+
+;%4$F!')6'(AD;DA(!9$!F'(84C1E7=AB.:DH*"+/
@r435
CATCTGCTCCNTCACGCTGTAAAACANATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAAC
+
F$C69=H,)#F:ED"C=25<83GC(BG#A%*4/AF+F=GF0<GA)!D7@0"0)(>72?6&<G:;$2<*1:*EH2'-"'C
@r436
GAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCC
+
3;7?7%-B/*!78"30'E)C8<>45'A!1:*,D>B''G267*G'!0*>7=!#12576AE2*;)#5-)6A%D"?'#D&&,#B;#=!G@"A2&94-#"("8%:42ED"7)E$4*H.>(&1'EC#)-*4
@r437
NCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCC
+
"7G,,&?A)BH3*4=1"'70)F,F'>,A$''FA%-G87(*!.$H
@r438
CAGGAAAGTGGTAAAGCTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCG
+
H71>?;3.!G%3?>@=E45;*49DHD%527D/.7?0E(63%A35C+G!(#22;F96H("D428+5H3&*=;3':1;H.9.$+9=H$2B6A6
@r439
GCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGT
+
2>22DD"8)10GGEAD!572!7+F,!C+$A.$=/6.(<43/12%9:&42?1
@r440
NTGTCGTTGGCAAGCGCCCATACCGGTTGTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCACCGCCCGCGTCCGGCTGGCCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGA
+
"+#+*&%&"*"!(#)#)+("!'#)$)%$(!)$*'%*'&+($%%(!%&(*+%%"!)"$+$'*'"&&(#!&))'"%&)'!''*#$*'(%%)$%")+*%(!(()!!&*+#*)&$'&"+%%$**(#!"$(&%%+')!%%%&)'"!!(('')*"!"%$+)$$"*!%&+)(!$&**('!#)+#!)"!*)*#)((+&)#$"&!%'("#*!%*#+*"#(*%"&#$"$"('(#+)%"++'&+#!"%%)*"()!$"!'&+($#***
@r441
AATGGAATGATTGGTATCACCAACCCANAAAACAATGAATATTTNTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCNCAAAGGGATATTTTCGAT
+
+--&!;(D!"(F2H?1G&(+!A,">":H5/*4#*'C)<.-!4FGAD6<3#2D230'4,@%4*-='=$E)/?07;:*C&?5BH%?<&/1EBD>6H"=2CF!
@r442
CGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAA
+
H4#?)*.A*%*C-GE/7F%-?@7F;/:F/<'HD(+/F@H%"<G9%*/)H&:)1'2A/F:-"C<,3H5/:>B0'7/834%)9;G-G7,=,
@r443
CGAANGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGNANCAGATAGTTGATAGCCTTTT
+
1B>'A#&F'$/"9.HH4!#3!,+6=?B<)-G95(HD(+<9:?<F0$G0('A5F7+@?3@+-6&4HE5+=,;,8#=?>E36?A5(&DBG>F*-!"H8&D<;&1@:*&$$D6(@+!:)6
@r444
CACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTC
+
335!3)&+&:=7:'E%.$2A&8,2'%'-,2.>C:@*E>.-0H")8BG#DC@5E#F*)F'#53>,!(4!$#&>CF8/."3A42,8.8CE:";DBA8?':E8-*@!%#?%*&'AFH'-BB,F
@r445
CGNCNCTGGTCGNNNTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCNGGTGCCGTCGAACTATAACCCGCAGACGCGGCAANANAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACA
+
($&(!))%('&$'%"'(+!!&&('(#+#*+%(()*'$($&$!%(!)%"+%('$&%!)#+++'*"$*(+(&(%!")%$(&#*("+'*%*&+!$$'%!)$$$$))'%"$*#"#++"$"&"%(#%%'(+$%"#*&(#%+*$)"(!($%&$(&$$*"'!
@r446
CGTTGTCGGGCGGGGNTACCGGTGTGAGTCATCTGAAAGGGATTAACGGGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGAT
+
0>"8'@80G#?=<&"@!!?-=E($$(D8E+A&C35=3+8&+=1,=5)B$G(279,>H!2G):1->"4GB66:&7!/D0<08;4HG#/=
@r447
TTANNCTCTCACCAGCCGGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATGAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTNACCACCGCGACATGTGTGTGCTGTTCNGCTGNGCATGCCAGGACAACTTCTGGNCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAANCAAAACTCGACCTGACAAA
+
%!!"$*&*)*+!##&%"'$**"#!'%)!'!&('*$&()("#$%"(++&!'(&%*%#'#$%$)!&$!*!"+!"('%")$'&&&"'""*)"'("!)*#%&%&+#+"'%$+$!%(&#**(+&'($!+(!&)('&!(+)%'"'*"(!(#+&#+*#!+&+&*($(%*!*%!*$)"$)+$(**!*&+)$(%&&#'#%)$"!%)%#&#%+'"(%*"%'!'(%&#!')!&%)&$&"')!##+(*')*"''+$(+&&%&##)#&+&*+('("!)(*$!"+(+$&$(%+'*+%$!'*%$"*+(&(+%#&"*"((#'+%"%+('$*&%'+')+)+!'($&(**+*"&*#(#%(&&'++'#(+!"#(%+##*!+"''*"$$%*("%')%
@r448
CCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTNCGATGAACTTCGGCACGATCNCGTCAAAACTCGCCATGTACTTTTCANCCCGCT
+
+'6EG%A>2##%FE.3H:-C98,1,3&E)3$9BDG%9B+8F&15+F;F*>#A<3D*50?'6>?B="<7''2<?:9=B@11283D6E/+5F6=.DF$(5A;$&B?*7-"E5@5CF<4$2@.:3&E$GHE;E887$E.E$76<:'C>1-$135;C;4,.0FD;<2-0;:(*6"4-C/"''C737B0$8/-42;EAF-;4>16<%BH!&7=B-0'F@>?3C<7.8@5
@r449
CGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGNTCCCGTAAATCCTCCGGTTGCAAAATGGAA
+
&A/1DH;A?$-).'0(D";2H3<1<F!-#+"C!%&)91$D"?E*2/,3?'$FB'5/D4&>1:<97%.4;+$5B999G.,B(EE%)GE:"83A!#5'7..;*%4B3<'9+%<%<<>-+8@G-'!'.<7#&,'4D>DC31,))0C4&;=
@r450
CTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCNCNTGCAATGCCCCGGCTTCATNGCCGGAACGCTGCAACTGANCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCNTGTCCACCTCCACGCCGGA
+
)'$$+$*+)'"*)&!$*'%*'&"#)'"'#$")#*"#$!"'&+'"#()#+*$'++)$$(%('%!%+!*()+&""(*'(#("'#&$%*!''%)+!!*"*&'))%$+!$($%()!#(!($$!+%$&&##(+!'(+'$$)"!)*!)*"%#&()("*"")!&&&'!('+#%!(&&*"!#"##$"+(&&**'%$"#%)"''*+&%*%!"+&""'+*(+)%)#&$"*)&()''*+)$("&"!%$("&&+#(*!(##
@r451
GACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAA
+
=)D5&45/G)>F'@,1;??DD42C4&0>9#*)&<5B%!@;H>?3)+(6DG?38..#'A/$2FD@=/DD1AB$!$07((6?H1F370:&%0'+2*'A<(
@r452
TCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAG
+
7#?8$H.-3+2F%'A2H#:D14;FHH'"@2.@%(*!45&5&G>;8E>+'GF=1>7*?-.(*!B!!"0F@$/B;3E*%$62)HE10(D67)5.#@!9
@r453
ACNGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGG
+
))"'&+'%&#))*"!$"*"%)&"!%)$('&")()!+(%*"&**''((&&#++&'+++$!#$*&$''*$+("$%"#+"$**#"%'*#+"#&!*!%*))!*%)%)#')!))(%!"!(!)*"!$%!&%!%*"($!*"")
@r454
GGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCTATATANTCACTCAGCAACCCCGGT
+
-(86G05!G+F!5!'H'-3A6-"=D@B-.;B,9=E#--2/F"83#6(H!):6D5&(B,:E
@r455
ATTNTGNGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTC
+
)$%$*'#(+*'($!%!#)+(%&%*#$*"&$&(+!"%)$#)(+#"##*$
@r456
AGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGA
+
?GA#+&*.1BB/71H&!8+$;#1C;,/8??$08<%!$DH+BG=F88;D$'#.=-/,>%(/4(17DD)F2A(@>#)1=
@r457
TGACGGCGGCAGAGTCATAAATCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCA
+
6E<*#0+81!+'@E."!H@3:/AC9'A/=$*2249!7#9?7E5+/5*%#3;85,H03-/1
@r458
GCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTN
+
!D,2#769*9;?75G**A<66E3#8)4-52@E%)44&?8-(8.($&9)5,*C?6D:?#%3<&;D+49@)!("H+"=FB>,:##F/1+D?1=3A&5"@59E5D16&#1>%E5C0.!8(
@r459
AAGTCTGCCCGNGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGC
+
ADH!'&:G=F)@!%E!,@;=>7$E2@A.,+AC;H5.>'A-?!8*9DBF4@D50$(='2F$:&6-F*3"CFDC
@r460
NGGNCATCNCNCTCACATAACGTCCACGCAGGCTCTCATAGNGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTT
+
#''#'))&&)+*!&+"*(%(+(+$%"(+*&*(&$'+'("+!"')'$++&()"%"+%"&)'$'#!!+*"&'&+&'&&#"'))
@r461
AGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTANGCCGAAAGGGATGCT
+
CA#D5<4,8(!*5%/C('C:!,A;'$;:;ADC$*F7;5$-%H9G8..FH-#1;!#'/#</,:)304E$'0,CD,-4"1(#768+EB3:=A;BBE1C>D+1"3-7/?H
@r462
GGTACAGCAAGNCAGGCGAACGCGGCAGTTAACATGCAGTGGACGNCAGGAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCANTATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTGAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACNCCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACAAACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACC
+
54=28&F7!@;49GB?'D<-5H')135#.G#A6,=C850(A;#=H1#7:;1$0=15=4E';295,6!A09E55%73A/G*9H:",$,/8!H@4C,)H=F$)=.&H><)"-1)%#8::298,B.@D%F73A<#:G22#$-A*';GG:+*3+C"90D$E7AG1)E<;&&60<63/>9-4F6-.8,?E>H$!E6@"D%6':#B(G<A+$3GD0')'#,D'+B,<C/2:23";90//D7'.:C$+$0"2#90C7,6/%?9$:-186$,8-?C%"<1:.2C&?#?D''37"G.77F#75:3;&-F:$")7
@r463
ATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGAC
+
B19H#6=D%(C7;A!+0D00>E><1-0'C>)-H(F37*A+F;E8+2&$>D(:3:1HA48">45;G0-.>!)-H,7#.3A#&)GD8?:BG&F,=F>/+"';'9/=>*46C@<E(2!8!>382*
@r464
CCATGTCTGGCTTTGCAGACATCACCTGGNTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATNCCGTCAGGAAAGCATGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATG
+
++$$(#%"#*"&$*#)+'&%$+$%%(*+*%*%*(#"%!)%!'#+%($*&'&"*'!+*"+(%***$'&")&$!%###!%"*((%&(*)%!"'()'$'$('))%&")!)(+#%&**'#)&$+"$*##)**'"+!$$)*
@r465
TTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCTTTAATGGATCATTTTTCCNTTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGNGGTTTGGAGGAATTGATTCAAATTCAAGCGAAAAAATTCAGGGTCAAAATATGTATCAA
+
B=D;>F9B?&E&D3/-)%&#%=&@/:,>.4:5<$.6494/)<8B.ECE5!,E@18,5!&C".0#-'@"2:)B9!BEA:"+2F8547&5A3>??F;5F=(3A57:');GBEF+9G*:AD$*@30=4'-EC=.$)>1+0:B$C/'()%:8=G=6B()(+53@,),A4F:!DE@A+.@FB>GH$@G958$#==!=AA71F'A5*G7"9H20=?),>33*B.A*/G'%%2F*->6HF/-/"5:5';>%6?%D0BGDD?"-3FF7!&758;B3?'9B$-C3E$E4*D'E.85!1
@r466
CGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGG
+
>%,;E(+/GF%6-DG&''3)DH%AH4E9C7E?27@-GD?F=*2.7+#9&<2>F2$-7F
@r467
TGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCNCAGTATCA
+
":!##-BA>66@H>"/!GF.>5C>)G07"(FF21H0)1A17#<?GD>6E:,*
@r468
CNGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCG
+
'$)+'(&++'(+*%($#!#&##+&"&''()))*'&$'&$'+*)'*
@r469
NCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCNCCACACTCTGGCTGATGAACGCAATCTGAGCCTNACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAG
+
#5AH/D@)7B*0-13'.&/A1$<7':@?&1+-:#6=C4:,.2&03?,70%(,:E6&H(23)CH,#H,A!/>.2E,H'(1805;A,;=6B:&G1%$79D?;8=89,E-G+5G5C0@>/0'.;B2'$#.D!(0B7'0=/41159C9%2<-178@A>G%9;BG8!43H37+5@6*>+6=AH>;-2E>42DA@6'G3&=(5G<FB;F?1H;)"(.20&&!A;72CG8D1"H0.#D?(C,)+FC0'A*$4,&1&:-::G<*&!
@r470
ATCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCC
+
"E!*:54&0*A#--&1D*)>E3DE")5>,*?&-"+;B4%HD)49$&:%,
@r471
CATCCGGTACGNATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCNGTTTCGATTACGGCA
+
%1/*)1%041/$7%A8/B,*@G:7?FC=$.@H!&=B#&=%-=2>E=+6>@&/50G%$9?9A1<91%'>A9F>;@6G<A<DG
@r472
ATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGCAAGTTGTCATC
+
BC9=4$6<?4&!F!;A333?;&BGF<;<-C/=30G?@)'797A2>D5D2+53$$.@"-?B1%.*4<FG2?1!<6<662D7+&$/'$5#;H%+29'@5A,
@r473
GGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCANCATATTTGCTCTGGCTAATGGAGCAAAAGNGACGGGCCGGTAAAGACGTGCATTACGTTTTCATGGAT
+
(5&;;>.>'>H8#(-5)366>'@*"AD2,-#1BE."<;EE+A2DE2@*2E9&<,<&8=:8!8.9'*E>%:>,0DF6%0B"@("857/>2"0==-/*<H=G$?>+E#&;+8(F56':#=0.A/>&86178+1/3C%57!GF?'@(0F$!#!7=*)'0D1/52(C%939D+5<H4+'D((C-5%!;#;$./A,<,$!,6HBHG6%7*;1)%=5:12$3
@r474
GATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCNGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTNCAGCACCGGCGNACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGNTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCA
+
0"HD<07D";+".:9'/$DH0!0=<6%0#5.'31C"1(:*>+84'/(!.%$+F:3E:8"EB84'@3:B1BE3(,0:B#1&H2GB#'0#9%#7%!:;$B)'<;*E1B-CD2!-6,%"G<3%?@BF@6)/1*:@84G%/)>-710F=B9H8C?2,,($&/3#0H2D:+F/-06">C.G1**":B?1310E,1;$+3C0055-)=-!9(,D5B1',%4@%3F@A/*??,354@(:G&7,")GD;'F:D=.C#5>7/*17@25CB8419;,(>7=F%0>B3)24E)?B'GH,AD:FE81"0635%6*,?,
@r475
ATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTT
+
/3)D2E73#;.#=BF6HF+3'@<#5((/?6'$)HA:>!=70%F@/":A*(>3?&G<
@r476
GGNACTGTAAAANCGNTGCCANTTGGGNTACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAANACTCAGCTCTCCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCTGACAGCCGGTACAACACGTTTTCAGCATGAGA
+
('$*$)'&*&&(!$$"&'#%)%&!$&"!*+*+))%#'("'+$#&++(%!)"+*&'$#*+)*+*"&$!&&!""+*+()%)(!#"&$''+(#)*!!'*#")$$%+%%)'%')(#!"(**'$!%'%!%'&&&"%+"!(#+"*!"!'*&!%&$$%'&$*!'("+*"!(+'*#&*+*+%!'("(*#)+&&#!&**#!(&(%*$!*)%)#'!"$&%*!*!+*!**+%)##(#%""$(##)("&!''"
@r477
CCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGT
+
%>9.22?@B%+2C:"A5D'3?H,0*1?8C20@29/&8=!>'C3@G22+,D?,8#5'80>)
@r478
CCAACCGCAAGAACAGTAACATTTANTATTCAAAAAAACA
+
)#+8576$*<25+81,;.A$"(@(7*13='6F+C.,,,3?
@r479
AAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGAC
+
30<AE4B5!,FAA"@-G&+DG%")+1=#*==.C9H.>2.*9#D:>D;;9&+0F2%+173*A:>C<69:H;G+CF/-)-(?.>!!8%9?!
@r480
CATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATG
+
=E1?/$)D4(C?A)C)#&'A!'5AD!%7?7;+=B"'2!@=@5+@2E",?@6;49;BB?&=F'/%?2B(>-@&1%%;C4;H0:@><93H&?D$))=/@!E8
@r481
AGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGNGGTGAGCAANGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCANGTCGT
+
D:7-/#C$=>1%$$569.72GB%&7FB@32,B<$7/6+*:6'>7ABH<)8D70?%"F(H4BB?@(=;-D?>::(9<&,AG0/D8:%38=,03E4)$73/;+2$H7$?#$7#D'7>)#;>)#23F2%?'GC;:%:G.EHF$A.?0F3;1AG9C$5&(2!"%1?-(>%D>+"F#,'*E2!>7F=0#*)=$BA@BECFE930C%3D;,'(;56A@DHG"9>;-A<**G5(2%@B2=)*7D4-?%E7C#F<)9F(;A70C1/?0;#83;10/-!:=,C"),+A5:<94+#%?,6/#)2F.
@r482
TAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAAACCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATTCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTAT
+
$&+%**"#'$)&&(*)($'#""'#%#&)"***'#(#+%%#(**!)"%+*"'##&()+#+&)*&+'%&))$((**))")$!!%!("%%""&*"*))$'$&(!&$+'%)$++#$+%%+#'#'%*!#(#+"+)&+"(#'!"&!(+)%%'(&((*#!&%##(%$)*'#&#)&)&&#&++**"&&&**'%)+#%"**#+()#"('!(#%*&("$"(%##(&'+(%%)&#))$))*&#*'##%&$)$!&$&%*+)**&+$!+*++)+#*('*%+!('%)'###"$"+(*((')$(&))'""+"&&'""%"#)*&**"($&$!**
@r483
GNCNANNTACANGGCTATNCGNCGNNNAGNAGNNCNGTNAANCCNACTTNNNTATTNNTGNTNNCANGTTTANTNNANGGGN
+
#"#"$"!##"#!"!!$$$##$#""$"!#$""#$!"$$#!!"""#""""#!"$##$$#""!$#!""#"$!#!$#$!!!"##$"
@r484
ATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACC
+
8B@!;+=.=)4%@$1+G!75D0''5?"5&HG=F4*)(C-6*G.C(
@r485
NAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAAT
+
"8?B%82@):/9%$5F.C#C,7/$?.?-,4A!G':92//+.2:<&7-*6;<,8+31,'=2>=A<(B4G>;;1;>*646F07B?B.>=:'073ABD1+;*9A+1@6>0>;$G+1BE>,#)AE(<45&0?>-?$?#HF3/%A*&268-!*9C<$>*9/52$<&%A9'#5//*,#C:*D)D
@r486
TTTGTCGCTNCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAA
+
>?*<>E,HA37/6AA(*-'%,7;4G7H(4,07-;)2746"9:8):0D&/>>':45;E:-;:,?+9A'
@r487
ATATGGACACGCCCGTCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTNACATAAANCCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCNCCCGGCGTCTGGTCACGCNGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTG
+
>4011=<:C(B!F@<F/B?12+;:;4D:!A&>H>!%(/GHA=!2A%195'"(B</>;65';@6-!59(,@4@";8H+$B$2=F$/2:F-2G3*8"=8DGA?<'B0D=GC!65<)89#&A#5(72+"60"#0@5D:H@6E"##'#*50<G7<E$:F=E&BG39:2>/,"?0G/D.B)8)(3A<&B,C4?%",@E$)DH&;G3E(19.-E,?B7=?5$)?>*E/+(/,3G;GC>(E@0
@r488
CTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAA
+
F&,:!-#..<)>000@#<E%'-G(%15-F0+;%#>DA?FC+7A<7<9.E8%6B$<"H#)E),5;9#?10;4!DD=&#0F0
@r489
GCGCATTGCATAATCTTNCAGGGTTATGCGTTGTTCCATACAACCTCCTTA
+
/=HB'/-?517=6')9?(H9E.3<)H&77G#GEG6=268"B(;3'3.%'#-
@r490
CCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACT
+
#E1@1)3,EB5!;"B,#/+8?>@#'2>@E;6G<$C*?D22'!<2
@r491
TCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGC
+
2H=$!.?%&0E.6:BE<G6=5$17,;4%@B=:-(+?'"(88"*7>A"GB5A921$1A<+03;#'5?E$G-(*/.
@r492
GGAGCCCCCGTGTTATTCGTCGATTTGGTGCNGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTNGTTTTCGTCCCCAAATCCGTACCGGATGCACT
+
)+%)%)#'%(#%#%)++$!!%!!+#%#*#)!)(!+)!"))!+('#'+$')#)(")')%"*$+**)*%#(+%')#&$"+)(&$&!&$&'$(#+(&"+""!(%(&*)*+*#&!)$
@r493
NTTNCGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGNAGGGTCATCTGCG
+
%(!$$++&$#)*($'!()(*#'%!#)(*&")$!'&$&'$'&!(+#%#&(%+(%"++!&$"$%)%++#'&)+&'(+#'#!!"*!"'#&&%&*&"+*!%!
@r494
NCCAACCTATCNAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTNCATTGATA
+
""$*+!)!#&+&+#*(('#*$(*!+(#&"(''&#$(*&!($!)**'''"'#"&!+%"%%)++$*+'*%"$'"!('%&*%"+++$*'*#"*+++
@r495
CTATCAACTATCTGATGCAATTTGCACACAAGGCATCGGGGAAATACCGTGGTGTGGC
+
A'>'"7D(&&">:):DA/3G&&5%C+G.D/7*$G?$AG!->58F"%1'8#D%<>B1;8
@r496
GATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTNTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACNGAGGATAAGGCCA
+
4*(CG.?0<&%E@A0)1.EC0>6$(1/->!-(?H3=/..<%>%<./,4-0)%<E,-FE%/C6BG.257,CH1ED-H1*CH0%,6$:%(=5"5&@0'AC.;./B1F$&6!DH?,%-&"4D4,BHHGB"+.DA&6$:F%6/7.>8%.:E,-**=D;&E13+(1528B@3,0G@7&8?*'+;<H.+&E1D5/09?71EA$!@&G9D996(*E8A1
@r497
NACGNNGATTGGCATCAGAGCTGANGAACCGANGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAAC
+
&))&"%($$+%*%&(+""$&((*#)%!#!*$##&#'$*")#$&"(&()%#'!)#)$%$(&+))&))!+$#*$!!
@r498
CCGTGCCACTCGGTTCGCCGTCAAATTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATNCTCACGCAGCGGAACAGTCGCTGGCNCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATT
+
%'"$+"(+#)#$(*'$*!')&&+&%$#**(+)(+!$(%"%"!!(*#)&*$"(+'#!+"&''%*()!(&$*(*&%()!+(**'*#+"**"+)**&#)#)'")$+%)!&*%(+&$)$(%($&!($"$%$$"((!'''!)*$&'+'"%"%"'((&$#'"(!'"%"*)#%)&$("+"$
@r499
TACTGCCCGACGGAAATCCCCGCTTTCTGTGCANCCAGCGCCTGTCGGCTCNGCGACTGTTCAACGACTGCCGCTGTTTTTTTC
+
B<(;@F>@6?-42%/&);*;;5!5>D:#7"#,=16D"9'F2;5EC&<-&-6.6:/(=B@5D*,#$+/79H=E0;=4BAF=&;,/
@r500
NCATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCA
+
%!/5A*E?.;'8&-=A6A'?)?@1F%$#!G8F)G6:!+-G&2H5-@4
@r501
CCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTT
+
++%)#)'!$&$"%'*%&''())+'$%'!&%"!#**$)&!!"$+!%++"#$+''%+(+%*")'#&((+%%&)#&#'+(()%+)'&"*#!#)%")
@r502
GGNACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACNATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACG
+
D(./=!&%9A&.1??6"500+%34>;B:C).69??A25997<26FA#$G-%4#%'0>DEE3!"/#&-?!D&8@/7A5&7&52E<>9/887";?&@@/@G;
@r503
TGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGCTGAAAAGAGGCGGCGCTTA
+
1$$9=)68B)&E&'1(H;=(;1F58("=E"@A<.H-(:B;B.53&3G+G#*F05/&)41C
@r504
CCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATANGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGNTGAGATGCG
+
7<(5)<?'08?*B=D&G;B%<?FD?<<3@F#.9#6G&2:"!%30H;$56@4/1*,!)92!0>'D=<%!G"'&"@B7CEDA!A)'9A+568<-@384>?F<=.0G#3&.78BD--7@8(),CD36C19
@r505
GGCCTNCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAANGCT
+
6''G-%C/>8H@;8#G:?@3-.@;!)C:=%8AD%G?3;9494CB5C!2@*?=A6>D<.:B0%2-9
@r506
NTTAATCATTACNGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAG
+
!%+$$#%"*(%*)!"')$%"&&*++(*(%('(*!#++#$+'##)+(&()"*'('+$(&!#(
@r507
CCATTGCAAACGCAAGGATTGCCCCGATGCCTGGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGNCAGTGGCTACGGCTCAGTTTGG
+
81$?452H%DDH"-?4F!<+!3=':''>80;73$?-,.;@.,5F3>&;>$%<2'/H8*&A2(A,GA=%/./H7)6:C/63/GG0.30%*H(44/445H0@D065,'&!78H4<#;98.E.43-B88'D)>;6)63,%7$1+=,,*!785E#*"5D?:3(&;A.3;),9C;=2!8$<(!)=B.@=<771(@<<35!'>,3(('=9652#FE(+FC0(&7D!9?9/B').7:#);FE8&'C<4?2)%,3,=,2!)/$AD<B1!3D,25@..$=%&G$<)A71A6D@G6$=H<@+)G6*/=&<F'01(EF0--3<#>1B16E:A7#*-H(B6A4H
@r508
GAAGTGATTACTCAAAGAANCTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGTAGCTACAGTCA
+
+&*#)(!$($'$"&&%$&%))&**$+%%%#')$%&!)$#$+'(%()&'"+'$*&'$$&$'#$**#*##'''&&""%!)%&+
@r509
AACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAANACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCNACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGG
+
G'=/93/58$)-=<H('+0-E5E97H5>6."F?%;$"*C:-2$)5H.++;>E(H%:,96DA3C;%%!?8E*,7@>DG996D=-2=/;C!<B(E34G??EA./:'32??H9($@)E4DD7)#$;B;,C4"1HH,+.4@%B@!"7ABA2,/2?HEH*/=(4/C&:-6
@r510
NGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTA
+
!#H+63&@?&00*AA*E218-?5%F1)35;4F3):1'&B='%#5,F=G490$8H.*=G
@r511
GCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGANTCCACCTGCA
+
ED&05+=$3<*4?"1F85%!9H3'00;64@*A0.?D()ABD49=,1<1?>777)5<A"%;,>B"B4,F@B0<;!4,81"2H3E+&(9/$"7417.
@r512
AGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTNTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCT
+
4><CH<<1A#+<F/H)7H+&F9*24HC?#FH$/'6,/.<;F3>/;4*:8&-!#GB:>/;:#A64:71-&E2G?19;84=,??(!%0+AC15%=8$%21=97#DD*>55495?$(B/G'"<!9)D#>.)''5A11E19E#86+*F=/>):!3D;$"-&F!E%E):,0:7%FD9'&*.C:=17/+!/F)5A%BF+#157$BH515$+8@33.?HED7>;%"!H$5A,+G'<>+G",D)%:;@A4>D1HHGG%5@"&2=:=)3"#F4;6(%E&7B!4F*F0$B7"2%?"6F?;1*&53;8A=.E@CG/??B@AB@06-<3E3"7"+;/,5(E@+=C#)G9
@r513
CTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCC
+
81((2C+<@)8&8</<ED5GE<1+.(C)#(8!)B4)=3B6A#=9?+
@r514
GTCCCTGTAGCAGTAATATCCATTGTTTCTAATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACGTGTTACTGGTCGATTTAAGTCNACCTTTACCGCTGATTCGTGGAANAGATACTCTCTTCCATCCTTAACC
+
4<@.,$>A41&(10.++9-7:411(0>F;1$>&FC.%2<;;%4909?+6/F)5*6'(##61=7">A">3D$$4/4/C:):E<@<$E3#:H;(F-=-3$D.'?6C@9HG6<')@;F:=E0<6>:152E&=')F:+/1=B'B;4*?.=?'?G29@C;5<&<CC;BA3>179!B/9C*G@'2
@r515
NCGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTT
+
"!C+1(=)01914E(%(E3AE:;392@G'0A1)@"<2A:&&;<FB+166%A><72&>$517,93
@r516
AACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCA
+
?9B:E52:);"A8B%.(H:A,4-&1G7>+%,49H3#8?CB070A=%08BBG"'D;'30/D$H<48H?+$"+A8E
@r517
GTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGG
+
H)2>FB*:G1FB"BG4DA@H.%2(C9')(8>%C@;9((HC?$;E@#;(9C#<H>9&30/4")
@r518
ATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCAGAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCNTATGCTGCCTGCACAGTTCNCCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGA
+
FC=";9H;.#C'G%$7:!?>?;.B=;C>;"H-9$(+B4=;"F-(-A%2'@A;"1';E+:=.=#)C-,&3(A687E70<,."536D/-36G&"F&#C<%)",(/3)5>E541'*.:.GB"5EFC1+;6@*C6@""*;@,(=,+*5?@=*<-/&.B/*=A9;?!3A91))?,>H-1*'@+,!-76<$G<154$H1F6/+ACB("(GD"1=($?<(46(9,7'*CE&7,F1G2DC,4B?1C0><5<'::-G10=2#(+)
@r519
AAACCCCCGGTANGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGANGCA
+
H$C794FF>.G;)F+'>"')/2D0@..@8-5%:,4#9>E744)"-?,**H>7;1<'2>C+<AG*6*C(2-/,?)*%.HB'8D";:C-2H9>/1)A=.@G0
@r520
ACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCA
+
?@,:H@&<H4'=;%/!5EG)C@$G*.9:FD4&#@=:$D!DFH1%A2H*D"$
@r521
CNATNANTNTACANCACNGAAANACNCAGNNNCANNGNNGCNTTTNNANNANAANATGTACNTTT
+
$#"$!"$#!$$$$#!"!$"#$$#!###$$!"!"#!!"$!!"""$#!!$"""!"#!"$$$!!""#$
@r522
NNCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTCGCAATAATTGTAACTCATTCCCCAGTAGTACTGCAAGANGTTCCAAAAT
+
%%5B8!4(,D/09#0.G5-?,7/-G773#8*H.C$012.(6DH:7%E5;<H9,2@5D-#0&<FH8.38505<$3@9!3%B5.3=2'<B@-&/.1/:0>
@r523
CNTTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGGGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCA
+
%+"'&(%!(#&$!&&$!"(%*$)'*")"'!(+"$!)#%+$%$)!'$&&#)!)&(!##"!&)%$'!+(!*++!!*$!$'+&+&$++&%#+!#*))!(+'+'#)%
@r524
GGTTAGGAACAACCTCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAG
+
8<-:"?;;HG@*A(CH*+<1*@G6.%<.4E-)C;3HB:AH25C1(2.>5D,C(72-$C%G22+EA!',!<#
@r525
NAGCGATACCGAAGCGTCACGGCTGAAATATACCGNAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTG
+
-!#?:H*>880+)@<@(4>5"%.F5H4=?&BE6>$"$A:99:$!).@F*@A8:293(D(:;$0!4>?*E4$*'83!:=)"AA<'<02+F0%E>>9BH@9F;F+/-3<.B=;+"F/8!$20$38.%-0F@(A-)D6)
@r526
CGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGNTTTAAGGAAAAC
+
3FG1%;8E$)7'063(05:2AC+%!%>F1"=.2C;D,.G+7.><H&.1#4#874A1'%/!#D'?F-37'B@!.-,FCD$''%24,@%@>BC5-*%1,)B2C(<,)+):C0#DC(@#%331D&(9+B@&28BG:C'H0>$B3B3H-"=<,0E0!!9F>9B/BE3H#F:9D-F("%H-=+'+D?-?/7
@r527
AAGNNGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGNCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGNTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCAC
+
E0CA16&F8'5D+!:442,,D1!,("-1*,*-2>/E<.*1?-='?/"#D$-3E"5@>?($0EC:$*0.3D&?B<C3FB:%CAB!4(,A/=H8@%//@(/>$7.2+F*&A77G"(;>6D2%5GD>0;&0CB.('4-C.9F&:F<FH*,'=.,."$=8#'*.17)(@D*7F*34A0&1-"H!9/3/4H%H?GH$.7(?-E):,#&!A6F?+F6B7>G
@r528
ANCTNGTTCAATTGTTATCAGCNATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGN
+
#"$(!)"%#($+$!+!+$+%(!%*)$$+++%+#&%(!(#)!&%"*$##&$$#('&(#+!#($&&&'+(''#
@r529
CGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCA
+
C2C'6C?9?D7!&)4'8"&A2?#29G8F,7'@FG'%$2H8:2
@r530
NGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAANCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGC
+
"G*/3#3A"E.*8H:!<;H0.F'(E*>%.B,(0=D1+F<,@0H>,D!*H8<),/4*+?27E4-?AAD<7A112F=6<C2278+"$.!!HEF3?(5&E$8(FF/??H8C8?A-(%?<$,F1"33?4;;>E+%*G!&=*D"(EAB<;=;$655BB>C6?#.D44B,C&,9!E2'%G$+(6:6";5D$GE3/):+H&#ED>3H<0$B3%$=+0&C,-"&-)-G?*!.;F@%=F9$A44&8-8%:%E:&0.9A#%"C'@(%#F
@r531
GTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCNTACAGCCATCTTNCGGATGACGTCCGGG
+
9,H%*+&;'BH9;&:)C,!H>1:15;E*.3C;:'$50(/':-D?.E%=4$?.A'&DB@,0%!,96->;<@8>C;:;AA-
@r532
CGNCCTAANCCGTCTGCAGGTTCAGCGAGTCACCCGGCATCAGGTGCGGTACTTTT
+
#"#))!"#'(''+&(!+&(("%&(!*#')#+%+&(#%##"&%('*+$()'&&*'+%
@r533
TCAGGTGCGNTGAANCGTCACNCTAGTCTCNNATTAACTATGTCCACAGCCCTGACGGGGAAC
+
(%*)%**%'&*''##*(&$#'")*"!()%%"&+("$%&(!$&)+"%($$!)*#&"'!++"!#'
@r534
TATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATT
+
(*++"'**"%"+$&&""*'!&#$*)!+')#&&(+%&(&%++!"&"$
@r535
CGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTNCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTC
+
ADD5:+18C;#?E6E8B;7'(<A:/#3>'@!@BB+.>)6G;@;,&$BGGB-=2E;4AF*/+EG7,E,E6"@%C<++E'>:H;'E=(4="-;$!#">051AFB@9?7G9/%'B:)1>?,*:.:6<#$",9>B-=9E#744=7H"6?&<&!1H#:(>!H>=6C?29F.;?(('@G=F100)0:5F!.13+B2,(=,%?$?3!CG+)3.@B$2E=6="D*EH81GH292$"<9"AE<@39168,062+)4HG&**E;-'!+;FH*5;1>.>2*!,"3;("#F/0!=H7"0H+/#:(=63'!;--;H88/D7>65'?,#/67"2=(1+69534!(352.%9)8%B1;+@:,?
@r536
TTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACA
+
.DHED'$C?$+/5CE+2212*B6,C%A&*5/C?&+:F/'6:)E##EC#58/2);(7D7B8A2/1G'<.A<"4FD+5$-D/'G3;')>-.D:/AG>='4#D:A(D5(6A)6>$8B#"8;G==:E<H91*%!G0FH6@:
@r537
AAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAAT
+
=(,%(E6&,:E"/.%;2&-9/H9:5*1,,".74$;EF0%)#50@&'(:0#$BA"F!B#!?@4H"'1?6;,?FHB;/3=!+B=.F9-(?'+(/1G(C&?D(-%!
@r538
ATAAAGCCGNCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAG
+
C(=E.<)3>4"?1:33)0$9.FDHA6C,,5/=HE9F?-E-E.>*!;??HB"%#<E)E"!#+/+71ACA1(
@r539
TTAGCCGCATCGNGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGA
+
2/G7(4.)C07?($C"0"&1C):.2.07F9$6.B$3E0'8$/$&=G6#1@&0??5@=2%=1CB
@r540
CGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCA
+
G>.;11GB$<.$4<%F,=.,9,:6-5>A*6!-2<6<9<GC;8=<#@&D4.(&*195:%%/.6$4*;3"!"!<%-./?F@#9>7:>9D;=>"A/=),',,2"!@"G
@r541
CGCGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAANATCTGGCGGTGCAATATGGGTACTG
+
+@B?+-276?$')>";/<H!,*'7E4&A.9A=55!EC!@20,9@C;-2,+2>A/;87CCGE&#51:;6!%H8
@r542
AAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGANCGATGACCATCCTTTTGA
+
0H&-D83F"8%=;+C"@%/H##0?.<>;G+/B3;D.57AD#"56<.;1F!F851(1H88<80=
@r543
NACTNTCGCCNTGNNCAATGCCTCNGCATCGTTCATTCATATATGCATCCTTG
+
&*&(&&*(*#))'%!$(#+!(%*&!#$"$(##''&!+'&(("%%*+&&(%$"&
@r544
CCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACT
+
>2E6;?C0?,;2A7C7,E(?.?5FDB.!H'9;)9;2'$4*49-.$E"<3+C'4D+G46'94*;.#
@r545
AATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCATAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGG
+
';$=7++)*.'=99#,E%&70(/7!#6=5D1).:00C@FAB!=ADE%4!$,GEB?D,E@4G-+!4,@/C6&F+3DF;1B"/5E?;7$>);H3:D-&857%(@G>H9C$FA6"+65*-%@*$0/8.$"A74:H'&!3D#!!A,<8D'=,>3@#1.1*6?D%2D1,."//+>+7>;/A)42HE
@r546
AGGTAACGGATGCTTCTTCCCTGCACCATGCAACAAACTGCCCG
+
)2G0&D!@:!@;B*((E:#.A=D0!>2@4-F1#).32.3.B$-D
@r547
GAATCGCTATGCATCGATCATTTGCAACGCCACGACTNGGGCCAGC
+
C4>$7H6G<*59H);>*,.>2C<"-@A2B2DD#></3*"3$G*0<4
@r548
ACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTT
+
HB>+C(HC1&&2(A4B=,#;1.-6H=48"))/%$',0?%CDC&2'2<5#'!3&>/<*G-G9&%'BD!)H@/8"54C8:A6$#,+"
@r549
AATGTATGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTNACAGTCACTCCGGCCNGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGNACATTGCCGTCGTTGTCGGGCGGGGATACNGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCANTANGAGAGCCTGCGTGGACNNTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAG
+
&0@1@=<H*AA+>$4!>4&(C@)-B089-D@A62=?ED8..$')0G+-A%%"!!.-%<;DFC),4,#(,*5>6)C75;<270-5)2:!C#((#0('B(:;+40>!C<!C?(6D4>-/+4;4./>D<*HH&-A$!"*".CFD-$'.'F#2>;1GA0&B&!."H%F282EGA2*-8!4,7A0!2)3B#7+9%@(E/.($*6/>A<4&?<?/.119>#4<$G?+?"&6#?>"52?,EA#(-,C+,17/D#3&#1G0F*@"$A$E8G(-@?8%*&&=-1895CB!0%">()GF1H*AH-6D4+/<&)2><(D<2&""5/>G>'F.+#"*#;G5@E*B*=3*@4(
@r550
ATAATAATCAAAAATGTATTTCATGTAAAATAGTTAGAGAAAANGAAGAAAAAAA
+
?1F)%),+5A:GE2?'>:)0$A-44<;6F/-DC1%AA&",D8375F53?9,>?E#
@r551
GACGTATCATGCNGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGNTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGA
+
:*A>0BC26;5??3H""//&B:!;59;49A;.&'08"5*/==?,;GHG:*H->>'?*7A:D):,(3$;7!8B)/;#<-"-(>/4(;G84)2=2**@%"%#9+9
@r552
GTGATTTAACTATANCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAAAAGACTTATCGAGTCAAGA
+
=;>$74"E68!'=,$*5A+!D!C$.-G%CC-+"7&DG;9A=#;H7%G;C5"B;CB%2$G36.;;3;*/!=9G.+1CA8$%G>?>D,114B68,9%++/C?'-=@&%0$!;*<.0>AD!('H&C+<.)#"0;G%B@B75;:7-+>>GH29B($F&A):B.FEH7=:///,8'GB9:9%7?
@r553
CGCGCACATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAA
+
C1>&H2"#;9C3:&55:E-,>0D#D%(C<%H.);'7790!8HG&D2?;B1D8=8#<,3C>=">5"<&>1E+F0>7.*"@.=(
@r554
NAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCNTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATC
+
"%+!*'%'((%&*$)*#+')))"!*"$""&"%'&%!()")"%+$$$+"*'"'!%*#&"))('&*"'+$#'""(&&*%!!"#*'(&#(*)"*#%"&$(+&$(&(*$+%("++!%!!#"(*%%'((##(!&!*(#"(&*(($"+')!&%
@r555
CCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCAT
+
36$4#@&?)&D,0(G6G;;=?7A#&H+@7'G2);0B@4ADA1GA1DD5G4(6&:?%1>)#>6/F5DF0F
@r556
ACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAA
+
*9;8(.;+63EA5>%2?F=7@!;$,@6-.03>&=$F=7)8;;3E%D<33>+AC%6,&=%C/C:;GE%F'#D1A=#=8H*1#B/7:;5#3&F*8>?279;1"$5+E>0,E+1=B!#!@G:0>02G"6$H6#""'.BBG9':$H%!%A4+=G89#!9::7
@r557
TATAGTTAAATCACTGAATCCGGGAGNACTTATTCTATTAAGTGAAAAGTGGAAATCTGA
+
+H#--)B2>2$3A*.H:3@,11">G2E=*=,D4F+D+*'518*75.5:CBH!;H-B)&:H
@r558
GGTTGATTTCTGCATAGCCAGACATGGGGNTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTNTGGCTGATCGGNAAGGTGTTCTGGTCGGCGCNTAGCTGACAACAATTGANCAAGAATCTTCATCGAATTAGGG
+
!$'+)&)*!(''(!%!&$))!)*%&"')++("&(+*&**##))&)!*!&)'&#%)&$)!('+$&&#!(((!&+'$&$&#%)')$*!)'"!$&$%$!)"%!!&#+*)+##$*%(&%##+!%#!)#('*#%%$"#%&$&"$))%&")+$&!!&#"%%+$""("+""(&()%"(#%%"*&!$$!#"+$$('%($(!*(&(%*!!+%&(&+#'+$)+&(+#$*!#(!"+$!'")(&%%"*%$(&#()&&'"&&%
@r559
AGTCACTCNGGCCCGTGCGGAAGGTGGACATAGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCNTCTGAAAGGGATCNACGTGAAGTACCGTNATGAGCTGACGGACAGTG
+
678G+5.*=<@A0=G=.A>?-E!-<D13,)%A"8E%-*'6,0286%;8E''F2C1/?<FG,HF'3%#B+3/62<#;A<&BC+E<B>)>0-.A3;8*/-<9(17E5(9..64,1'?+4D#H=0*8:)A2.F0.87@!#1$EE"/7E%(H6AD4C89CA5
@r560
NATGTTGTGCAGATCCGGTGTCTTGNCTCCATGCAGACATCACGAAGGTNTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCTTGAAGGT
+
!#$)+%%)#+&"(%"%%"('%#'++**(&(##%!!!+$+%'&#')'*+"#)%"++"%$")&&&+('($"+$$*("!%'$+**''&&"!+"*&")(#"$&%!%!#%
@r561
CAGAGCCTGTGCACGATTTAGAGGTCTACCGCCNATGACAGGAAGTTGTTTTACTGGTTCAGGGA
+
76@CH5(,=EB3)-8<6"H-$.',63*+#0?:E0$)5?9"18B"C&F3E4.E)<#(D@B?$*.-#
@r562
GTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTT
+
.?1@@C-$A.2:,),:53"D*($?-GB/'2%8%;C*;&<<7E=//820+(;23*6;FD,#H$CC165G4(2)2E-5/E0%?F;0::B;!H
@r563
ACATCGACATAAAAAAATCCCGNAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTANAGTTA
+
=9/2>'&"&=?EEC!&)5*+H6>B.<7+6>75D+H*>6$!A6'EH69"0H37:;+4+.4A;A;;'#*5
@r564
NCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATC
+
$+$&"!&"+)(+"*&)&!'*#)+!(*#$+"&#)$+(##+#
@r565
NNANTANAGCCNTACGATNANANANGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGCTAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTAAATCACTTTTCATTCTTGCGTAGCAATANGCCATCTCTTCAGCTATCTCAGCA
+
%#*$$*!&$"*!)'"%%(#&'!#*"+)+$((&#('$(*$#*()(%(#%&%$'%$(('*!&%"'*+$*##(''(&$#&$*&#(!$''$##!*$)*)%''("!&!+'*#**+%!*"*"(!*#('%!"'())')&"*%+)*+%!!)'&&(%%+%"+#!+*&+*+&!"%***%&+!&!#!#&%)"
@r566
TTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCACGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATCCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGC
+
H@+!7?8A-=F(-:=!DF5G+7C-%.<%>9!12&C79?CG!*9$+%$C'#2CGD?@7($&6:F(5C%9%%"B9/;;H%+&&0=;/8,F*5GC=&=#C;G")9.:G:-+4D=H@3/>H6@;AH$C7%0A6,*96F9B;949DH$G68!;#&)0,'/;F)6'G17;,90)7)B69#)$?C@$4>>1C<$A)5#6B>D.>58HAEB2H=(H"=1/>?EAG3D;@--B#.0:DAH,-FB?+3'<$&3.=%1FC%4<04#/:8'&2*7!!,:G?5-;/1DE:;0,'821F=%!0"H4!=8C9B9?H>237/EA!"%((!;D"2:7CHD7</89E,3A.2F44(
@r567
TGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCAT
+
$'+%%(#%+*'$#"%$(*#*+*#"!+!(#+''(+&(%)$$)+&(%$"'%'*'%$
@r568
AGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAA
+
9GF*D?):0.='>5,;-"G"@06HB;<A$H'>#H%9FC8&:83?9(7@C3D%*=8/F&:H>9G&"-=#6&E93=3)<=4GE7CD+6>
@r569
GTATGACCAANGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTC
+
39:"=2"G<3.).$#47=,84-05/9%0!E!,3828C%$)3BBH!8B+:E0#&/!D@"A%.08@+;!H6A!E.<97,A"+784/,%-)%8#.0(A@":EDBF6:(%''7"7C*C+4*B+0,-C9;8(%
@r570
GGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGT
+
+$!*"&%$%*'#&&'$$&&#!)$*)#'$(&+$##)$&$(#)#((&('*#%%&#&*+'%"#+&+(&"'((#+(&"$"!)&*$&#
@r571
CCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACC
+
=:@%AD/9@7,..";/&A?0)/!'87'3(FB'"./6$D4F(E$1"/8/)DF5
@r572
TCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTT
+
+%)"+)&)'*$+%!'*#+'%#&)'")"'#"!"!**)(#&""$+##&*$$)+%&)(*'%$#&#+$%!"++$!!&#&)$%&(&#$"&'%
@r573
GTGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGNGCTGCCG
+
#A'A-"2"%&C!0%7#87EE8H"C'F@:?@#+.6"><,.1H/89,%'5%/-E".&/@C81#D
@r574
CAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCT
+
+%!*+#$*"#)&($)*)!'+!('&!+)''&&"*%+*!&+$)%&+!+)%%&
@r575
NATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAA
+
#C)4"C)B(E'>=8"3).D0AH+6>3-C*6FD@@5B@2BH<@:#D:/F@
@r576
GCATGTCAACAATACGGGAGAACACCTGTACCGCATCGTTCGCCGCGCCATCATAAACCACCGCAC
+
-$6$4&&*5?C40-%;+0)5;8?="$.96H?+E'8/?C;>+@?548?*H1AF&F""5:A6B(?*-/
@r577
TGGTTTCNTNNANNTTNGCTGTATAGTCAACTAACTCTTCTGTCGANGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTT
+
)#''$%$'!&"!$!$$&%+*!)&)$%!+&!$'$('!$)*"!)'(#'*)$)&%%(&!+!)($+!&()(%#!'**)+)$'$!!'$)%")')!''+))!
@r578
TTTACTACCGCAATCCACTATTTAAGGNGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACT
+
6=-.2)3F=@%G"6#'0H,#CC9;*8F"!F15:3'!,A';C=7A#-2;?BE0H0743(>;<*0#>>@04B6;EC79C@?A'C62)"7467F;B<CE!G/A?0>;$
@r579
AGCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCNGA
+
:53":E3AG*=>37+6/-E93;#84G<D><@.2%985>5$)'>:@
@r580
ANNNGCCNNCTTTGGCCCGGACGGGAATNAAGTTATCCCCGCTTCCCCGGATGTGG
+
'*%#'%)$)+)&*!*''#&*%!%#$&(*+*#+#'++!'!'$$'!&"$()*$&"$"&
@r581
AGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATNCCA
+
BE=G6/7*"D)B4!)H;1;/+0:%$*586>>*0(FBE?(1H*F13?0C,+C/7"=.B3H<=F@E+896+=>'9-8+7%
@r582
CAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAA
+
2;&G2);E.)+8E@2+'<BFG:@$E1.8&/-BH+174G12?*)%(D0.G&E?;.5;9B:)$H#HH'>4,2/$$1<,5,2'6-6#G@3GF?05<0EA&;(:>"/<=;H1">3A!
@r583
TCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATNGGTCCACGTCT
+
B1H(#:.93..)%(E65?*,D6/,(1!&#G/4'7G89<(;+>*<2&5;*A3>.>4:/9F#::'%#3/);$F)4))<727%0%#E(5=)1B>AH0,$382D<*!-3
@r584
ACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAAT
+
BC01$<B,9=F%!1DA8;)'8'@-8?,'<E%8"%<!:1#A7,G14$3(3..62D+@-!A7>"/!@7(@'
@r585
TCATCATGGTAAACGTGCGTTTTCGCTCAACGTNAATGCNGCAGCAGTNATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCG
+
5"?6&F<==#?B05+H.,(B@,5D=1$H;=3+3),;C/EDB:(%3%<6'+G,4";8!#'?")E?6EE:..51"H:$:>#&F"EE7?.'
@r586
CCGGCGGGTTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTC
+
;.&6'/2=@E:D-H>F/C12/HH#((;;BG38@1-A0");8+%'==/E7B!G!+)7@79>4$!&D&=+:666
@r587
GNGCTTCGGGCTGACCATCGGGAACTGTGTCCGGAAAAGCNGCGA
+
+*(!#!('&)!#%$*%#!!($"$**)!+"%&*"#('++($!*#&*
@r588
GCCTTTTCCCGCGAGGTTNAAGCGGCATGGAAAGAGTTTGCCNAGGATAACTGCTGCTGCATTGACG
+
0C/*F,=FB>(4+*#8'&EA&5CA?%C%0$':,C1'".#--,1=7G7&5+!5-3.#>*AA@/('3;H
@r589
CATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAA
+
>E?>.>E24F4%.$<D?67@)D1=0B!++?4E9.-!>?="*%169=?/@AH'7/)AG%C87>.H$29$%&D&3D;FEH,736/D8<:/$9<:===#A#A)$5>FF)@*.896D4&;>H%/%&8'/=5H1/1A
@r590
GTTTCACGGACCTGCTTGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTNGCGCACTCTTTCTCGTA
+
1='5,&.*:)?H?7?):+%+*9D@DE)>#=G54?F%C8=H('B(<8*)<.0%-,A>"@4FG6>:2$/1
@r591
AACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGT
+
70?71F"?D:(;37D!:%,/'/!"4C06-8&.D9%#-(.G"@>4H<G*'=?
@r592
CGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCT
+
=834$.B=,A!*3</D;F'G;DF=.%:D<&0?>&FH#,+,)6(00'09<&;@</,=/46"@(#$F
@r593
NCCNANGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATT
+
%$*!((+'#!"**'$#(('$(&#$%***(""$"$&%%"*()*!))*%("&+*#*%$"%*)!$+'("#"$)#''(*%++**!$&$#(&'
@r594
GCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCGGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCANCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTT
+
F#!A$5C*/<(E/D(!1%@G8H,9@2F;/$*.,7+7,13A6)4*!:.9+()&55%E4<>-9<$'*C35*%-,9CBB+-?A4?'G:7+@8;C071*7BC.9/$+DE-C:1@1.7H(,50@GC>B@EH$/A!"("3;2E$C$0*7"!!2&+E%$4&"7&0?91<F)1%5)GC8:("B;8-F=8G+6+6F(*CBHG6H09H?+B7/0?B7#,7HE-*::6)')?.?C;"!!<(<373H58=00D@((<-#'!8>H%,68B+E.:2;?%B1:=5(4.'6(3G(%4>D/1E#78!'#.(7/'="A9-!95(D8:>,DC!(:5BD$
@r595
AACTAACGACATTTATCANGCAGCCCTGTCTCCCCCTCTCG
+
;3+D<67#2EG4G"$B=,???*:B!(4!2D?0)1#?<97"4
@r596
GTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCT
+
6G.!=G*;#!&H)C:H4$#5=.95=(67DDCA!C/?5"'%"!%GHC98%%%4@4"5'
@r597
CTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGC
+
630/5/?AG>8/?3/%#D!%'D?(H0EC$"/F>,+HG(%#5$9!F@C.H
@r598
AGTCTGTCAGTCNGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCATCCCCCCGACTGGCAGACAACGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGACCACTNTGCAAAAACAACTGGAAGGAACCCANAAGTATATTAATGAGCAGTNCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGNGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATGTTCTGCGCNGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCNTTGGTG
+
02G1?#60#4=$<"2<78!=4:;#-DA($>A(#,G/EDH,6+"*:)3-CC(G";+2F+H017A&1:;1-G4;4!!:**'"&98&.DB0:4386:0E%,%3()3/?='B<&@#)1D?-9C8"48;E#0%47BBGC2,C@5!A(>1B.*9-8.7,-/B?$)BAB%4".+=A:A<-;D5!$+=H/=*?#-HDE%/H9>$GE!B?0H'4+G/)+4(G"-&58H:2/G=%D396C=H23BF"05149($:6!-"G=0"9.#7>H?7;6%+.#<>,BD980(@#0DB;""BG3!!8;A40?C:F+$CC4@#@1/5,12223GB?59B22.:,0H;62/;3@5!C>+B=-FH'B+**-/6B!.04.1C#3?8-D?-"H86=$7.H")!6G>5GF(AD34=FH62?B7'+<
@r599
TCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAA
+
BEBFF-8H<BA9.>'9<(>&1@:6)D;.6C@)<*?A+1#&#3(
@r600
TTNNNCCGANATNGNNCGNCTNCNNTGTATCTTCGGTGTACAGGCACTGGTGGAAACCANCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGT
+
)*$!%$!)($)#('!&))&*$&(!'$!$(%+'+%&$!+")(#'!)"+#%*'"(+"$&!"*%&((#$'$!$$"&*+$+"*"&!'+*)&'&!'%%"%(#)&*')+)*%')%!#%+#&!$''&!
@r601
TGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAA
+
.@"'5:-*@*:D:):-#5C$D*4"@$-@H3'-78+8*A+<F8%.F@?G98<B29>%%519&)045D?0/E735G=2-D39D9=#7;)5>-;0.3E0EE'$/>6H>0+!:-@!33&8#-)E"7$68@45F=03C=*F<C,=@74@.4<>=26-D5'E-0;08G5/D/3=F((4*B5<#C6C*2;*<C6H
@r602
AATGAGTACTGCACTCGCTACGCTGGCTGGGAAGCTGGCTGAAAGTGTCGGCATGGATTCTGTCGACCCAC
+
E?A;1H>;$#,0?(B4"!B8.F@7C=((@?$$),A;B@%G'(*;*0DE2"E?CD3;>;;@>*?<:=))(8E
@r603
CCGNCATCATCACCGGATAATGCCAGCGTCGCNAGTGCCTCCTGGGCAGTCAGGCTGTC
+
'+===H13#G>B<":$)!G=0A/2A/2'&@;=/EH!"D3<2@5F1!@2#A#&FG#CCDE
@r604
ANNNNAAGNCNTGNCNGNNNAANANCNCNTCNTNAGNTNNGTNCNAGCNCNCGNNTTTCNNNT
+
##!$"$!##$""#"#"!!"$""!##$!$"#$#!"#!!#!#"""$"###""$!$!#"#$#!"#$
@r605
TGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGT
+
$/G5&7)'%C"D.FF362#=:>1F>FH;?$C9!/+=BB>)8%8.732=?+9H!,3;A#2<:(F%E>F&49*H7.&
@r606
CACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTNTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGC
+
<*A8--($.4E*EE5**B%CBACE5'2"A.+>51BC)!-#,5F9;88"/2./35:C6/4A6BB++728423#;@0G,7"<7?2B%<0H891/C5/+21B9*E/'+=@/+"'-
@r607
GGTCANNACATTTTCCCGGCTGGGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCT
+
('&#$&)+%*+%#'*%$#$(#'()"!%&"(&)(!"$!+)!$''+()"#)'+%$(##"+))*)*%%%!"&%&&#'*#++*!'**))*+%#(#!&(**%$#$
@r608
CAGTCTNNGNNAATCNGCTCNCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGT
+
'))&#'##("&&*$(#$*"("*(+*'(*''!!$&$(!$'&$+#!#(#*'($*$%!
@r609
GCTCTGAAGGCGGAGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGNCACNGATG
+
F%#(1-95.,B),!B;3=:#,)">"13?;"F1B3F8.1E4-G-A*GGC8+&,6'!@.CD"3@?
@r610
CTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGNTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATNTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGGGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTAATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTNTTTATCCGGAAACTGCTGTTTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAANTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCCCTCATC
+
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
@r611
NCAGGGNTNGACTNTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCT
+
!)&'))'*"*#!&!')+*%#"!%*$$&"*'"'#$!$$"%(')%(&(%(%$%*+&'$*$&*))'+"#)+!+'&&###+)%(*!$!(&*"
@r612
AAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGT
+
50HBD0?!B)5B??:(E>:9.5,,G>()!?+E,A;C+/=0#*6A@%/1!0>B46&*/
@r613
ATGATTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCNCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAAT
+
=(/*FG0G@B*6C9+/*DH++9G#1*(E=F7.0!6".#>G;&!<4*<CF31A=D*A(5H?70+6+%)4E/#?#)%"B4G<%<<D"638FCB%C9%:D"B
@r614
GTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTG
+
(E'73B),7C2((*%%>F1!?B8?2)."F0&F5;1"48F,/>*,0C;
@r615
ACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTNGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAA
+
9&#*&#3&0>,$":6*#?6F&FD1&)5:6G>&D:6B<4:7#D>F1A<3+/.#D'>%83=7@?9,=!*)C<+:HA?/%C:4&6AD;F<;-F-4%C):2;,,F1#>#"<)95E,,-5!4H69,H=<.=E>6#:,,&;149/EB.A)B+0"H.$-1E..&@>-5C
@r616
ACGCAGGCCATTGCCCGTTACGGTCGTAATGTTNNGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGNCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCA
+
;+H0+C89.9*A67.:D//;+217.>H+1!!.)#F04G#;?1?$),G00(:#%:':!<B<"&$6(,D@(*B?&+>!=,4;108B';D2$-)AD3!F$/H@($+0"#AH9",1"025'G!/49
@r617
AAACATCTGGCTCGCCTGACGGGANGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCG
+
)/(.-A/CG3E19/20A==$47*H&F&4.BCC!D%24$#6)'<?!0FDFH?@508(A""'90>&31*D&+7
@r618
NGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGANCAAG
+
$>9#C94..3@$1BB:/<7?G"2*&D%+;:>*@D";/1H+'>1E(G*G,+=!A"G%<GBH;".,3*4&6/@1!>2#>GD(@4
@r619
TCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGA
+
);*C)0!D=D<D)2#45>E?85ED.?C+=9F*5B,6*B;F>(DB285)9&(51'$1@%$&6(@=0G4%,/F?;3*
@r620
CAGCACAAANGCGGAAATCTCGTTCCGTATCGTGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAANCCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAA
+
+!!(+&$'"*('*)#((*%"&$&&'!+"!#*$$""")&(%)+*+'($"#&!"(++)(+')$#)!&##&((+*$$%$#+()!("+#!$'+)%+($%$$%++%*"&"(+$%(%&("##$(#(*!)+"+##(!"#(()"+%+*#"$$))$'(*'&)*+*
@r621
ATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGNCGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGG
+
#)8@=9A-(1>61*:A(.0($.0"D:(#1>*:$!(:4H1%4<5;?0/2,<4F;4A8.;<90G'&=A@47A76<F2H4>,23%'1)GB)/<)?%:2F
@r622
GCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCC
+
7!35D.07;>C37C*%G@97+8B*G#:"?H#-B$11>H7:%G07"8FE?7>CG..C9#'#F87HFF2G32BD06*B'2/,3#+5B),#***%0HCD;&C<D;(%G-21G=(B!15<"#?09='H#!#.7=@6@(9FC:0/E,0#.743-6,#*.,=??#H2-03,44<F2"84=;8DHA"@&;C4B1,6H,#H>>G6)("'!?F4470/>2GC'?<,E-
@r623
TTATGCGCGCACAAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTNTCACGAGTTGCG
+
3=>!G+F'H@!-B6D&36**,)FF#&#,&@,A2*=@+49>4400*((7*9H)-5;A(C(@,*,4D3/
@r624
ATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGAC
+
?EB++<$:G&A2.#=!;&6A')F(8/:A<,!$9F52%/*2D
@r625
NNANGTNNCTAANATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACCGGAAGGAAAGATGAGCAC
+
%$#!#"$%*)*&")(+%%+"#!#*)+"&+$&!"+&&'+)%*$""*(#&#%!*%(**")+*!!%+*"%!''++++'")+(%$%&)*!&+)#)*$)')'#'$#+'+$'&+&$#
@r626
GCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAANAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGNAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACNACCCGCAACATCCGCTTTCCTAACCAAATGATT
+
)?236.4&$BE$A&44*G'4H8;."5A$#48)6C&>+$B*0(,-&?363DC!E&7&%#G/872B.-%#EG0+0?<+$#2H=/*E83&3.C7/0(?,.5HH&,@=7)7A3;+.49%"#"+=E!0H>,C@D9@;0?:GG<'@%D"HHA(A$>HDEG0/&0+;:2C&A$B<1A@DC7$$,?E-5/@7'(&4*?D:(
@r627
TCCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAA
+
+!-DE061=.02+@")(>@-;&4$E.AG/5HB;2>!D-0>/#5.8:D,(=!5964BE+5,+#DB#',=/9,G.E@2>A4#3,7$.28<B=$(D"2@0@
@r628
NCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGACAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTNTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAANCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGC
+
!-0;(.#,>2)(!*</>")/E/E3!4":65<(=9:$0"4E$0+=)"(.:2C#D,H>!/&%?'GD/BH68>&?77.H)1B7B:(C2D7>(9";#5639BE3=17(;:!&C@9D=9!-?=<H==,1H>9E::$6H6(GCH-A=-%@3/B9!4.=>0AG>A)5;,>=#)B5+D?8#!8B,F>'4-'>/$#A76&G$$1?HB6B;%D6B3A+#:HA+D8E?#CB(/3#8$-E#>*.)%5=;23*>40>>;&G343,>@.'")%59-A$)88C@-*)$24#0"*DH"!F<+.G+200=E?)C=9#(7A?013$D+&A;6
@r629
TGCTGGTTCAGATACANCGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGACAAAACCACCTCGCAGTATCTGGCCTCGGTGGTNATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCNGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGNGCAGGTGGACTCGGAGCA
+
&6",;<B=;8>'F":>.4*850.A:7C3GEF-+/G47D>23A7A"AHDH*.)-4$@B4)(46;-">#<9640F&H:#G*'0;+/8$121()@H#-+8@#+:#G;)9&5!@!8)HC23@0H'-)?<8/9$9FAG-7$97.GD:%++302?3F%"1A>H"*=(7C4-/;.,<?<9A/74(2/&=<"97298G4G%;>D8%@='+5.@0C@G'C4!2+<(51&B.DG(;H<7B3-#'-*9*1;;,C2@@+106#D7E>:0!D+69BG&F80
@r630
GCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCNCCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAA
+
29<@;$0#50*"7<<>C1?*)4,++/.779CG,5C.B.+8:'G";:4<AGB@1=B#;5/!;1@%G7)<!6;EG;84+D8=,'<H1F'CHD3
@r631
TGATATCGGAGGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGG
+
2H&A;.@H$7.,1FG:*;96BD"-<60,)=1*A215-!F;@&-&A9!;0*F:A-91#7.1=<85##!CD?;D0"-H"B&BD2#7AC22&5=8<
@r632
CTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACG
+
&/%$8/9//82'*A81A03:7E=:&?,3=B6/?BGC?@:#)17<49$D-9)>"A,,?>&)0,737*</9,&*<#4$07*AC/0?90)6+457<"8.F)+AC!A<:'!0#%2'('(H)7B@4&$3?,"$C.2?
@r633
ACTCGTCGNGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTNCACGAGTTGCGCAGTNTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCNACATCTTTACTCGGGCATAAGTCG
+
E9*<3;5:?G@:F<C'/E%$E$;'"C::"'00B;"'G8#4#75-;;E(5<08'?1.1'E8?G2.8+%9/56A%>>+0*/+H0??*(7>E*F2*H*B43"$*+8-,5$7)(-&<)F.0G'9:79**35383515*D:$>/'76:B)$004:6#2#?E<A1%9:$H$0+,%@'1&1**$?@B&)8F3
@r634
AGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCTGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCA
+
3&8',;@8?(*.)D!'"F,@1$A/#3A!5>.$E1'89G'9/$7C2>>%87/1F4>1&<D;4$#,1-.<7(3D#:9"@*F+42557/--)B?6!54F&1@(#%#'.GHBA;1(5"663*'CGD<(=B+8+@3,/=5D0-.;)6#1$&1BB(B=*$&!140A*C"@C8,>'6
@r635
NTTNGNGNNGCAGNTGGTGGCGGCGCATCCGCGTCAGGCGGTACNGCCATTCAGGCCGCTGCG
+
$))"**&###)'*#+('(!&)$#%)%'%$%'*!*$&(&"%%")*$!$")'!'*()(&$%*!$'
@r636
NGNTTCTGACGAACCGCCGGGAGCTGTNTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCNCCATGCCCGGNGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTAGGCACNGATGAAC
+
$)##&+$'#!("")'$***+*)"#'*$+'*!)'")+)+&+''!&++%!#%")"*$&'!%%+$"!+($")*%!#'!#+&&*$$$(')*!("*+&#&)!+#$++(!)!(*+!'$(&*&*+##%*+")(#)(!&#%*+*#++$#("!")"#&)++(#!!$!&*#$%!%$!"')"'%)(%))!(&)"$)$&$+"")#%'!"+"&+(%*'!+'''!'(%)"&$+'&!%$++%"$!()+$#'%()*!""(($"("#&!""&$))&+'!(*
@r637
TCGGGTAACGGGCAGAGGCGTTANTGCCTTCGCGCTNTGCGTCCGCATCCTGNATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGATGTCCGGCAGGAAGT
+
<A/3/B$40F@3?4/%23196>!>1/.5=-,1>:8E?54+-.C-+&FCG+<)863:0215@CC@0=8H,D@?*.7C(<G1..E<'("@%2C6<;:!-F9?"7=CH'7F705)<<#:8.>A&EF
@r638
GAGATAAAGCCTAGGCCAATATCTAAGTAACTAGATAAGAGG
+
C08/::.1.)G048B:2"D#-DA,1@89F9@56$B>'8B5!E
@r639
ATGGATGAAACGAACAGAAAAGCCCACTGGACANTCCGGCACTGACCGGAACGCCAANAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGNTTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTANCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGNCTAACGCGCNTGCGGGTAAACAACCGAAGAANGCGACACTGACGGCGCTGGCAGGGCTTTCCAC
+
#$*'+"+&*#%))"(($+")(!)!)(#(%)+*)+("#("+'))!"$')&*!((**&$$$(%$&%!!)!")'"')"(*"(&$'(+&&!!$$!$&*!!)'(#!($"$%%#*#'*%(%+&+*"#*&&'+((%%(+$!'!%)*)"+#!("%!$%"!++)"*$$"&"!#%''$)!$'&++$+&$(*$%'$&)%")'+(&&'(*&"%%)!$*)*+!$+$!&')+)*(+()&*)*%#')%"*&"+"!$"#*%(*"#)*+$%(+)#(%&&#!(*"''""#+$"(&))#"'"!&'
@r640
NGTTCAAATGATTNGGTTTNCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGCAATTTCTGCAACCGCANCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACC
+
":C;H&#;0(A*C;(957>=)0F??.)"@.#(7*B%8=5;=%"!E0>E<';:;%#-$"A/G$*-(>""14@2(B+-+:H3#*DG//76>C<9$GHAG."<;;>4@AG,)7--;'1=!A9<<./CD<<,(-C6B0,16<:;*6!"(1')/H77C;E
@r641
AGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGC
+
-GE&%AC68(D*4AG42BG761?E"2+=';<3H:D4:10;>AB4'/';B*&(E'(,7(C%<'@+5B*=?36@.H,@35A!CF"2ED:-!0$)>E3E>8*/+C@%3#;:+891'17?(=#"0(BC!BC:B51A
@r642
NCCTGGNTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGA
+
$'(*)$+&(%!"&&)"*#))"%&%(%("$%%##$()+**"!')))"&*&($'%!%%)+'&$!+$*$
@r643
TCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAANCCGGGACTCCATCCACG
+
38&"9>,;9>=6-2H>@F5<41,(5;=.?C68:%14E(?E<'1E00CDBC1<()!CA&,%
@r644
CAGCGCTCGGGAATGATCCAGATTTTGCGACCACCATGACTAACGCGCTTGCGNGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGNA
+
E48.)A4CB<9";'4H5-,4*$C3F-3:0",@GH=,F89;26>503!)E)&<H=24+4*6>3H&,:"43?3BH%5H#./&*:DBG;$:'=$FB"1<F-AA?D+#CF*CF
@r645
ACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGCTT
+
H(C0864$,$1B"'#/H=$B?H6GA>GA)D9&#48;@?9%@H9,!-.B4E>(7
@r646
GTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCNTGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATNAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAANTACCCAAAN
+
7*?8>=8?F14"<4?/0HAD1?G%H$4%*11#A8')11F.GG)9?7D?#A(#"3"8&=@2-!"2-#'5,E*@FB9")2E5#A?16H,)+&#-'#C4A)8%=5")@+9?%),26;:5%E>!B-'=CDC8'6D'0885@:H$%<AA<5>3($)<$FGB6AFE5,8G+E:@6CD%GE(G8$$D4A"<,)$!!.H"AG9@A-+C@3,H57<2/+&1E0DE59#;8.H8:
@r647
TCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGC
+
=(*D;5F<-B6;9E.)(E4C.A8?3D/"BC$A1F6?>C2@)HH8,/A"1!+*!(.>@#,!CF*#+'C99%3=<4B!@*G-!B$
@r648
CAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGC
+
9H:4!?E-(?;;!7=F1H9C('$3-.04,0D(;D=-$&C1
@r649
TGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCG
+
20;*H$CE#F589#195)+E0>+D,-G>F4*=6%1"E@/*F=64987--EC)27>BH&2947D,EH&G;7=1+</$6H3=H,7*DF!/>?1,-/
@r650
TTTGTGGGGTGAATATGGCAGTANAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACAACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGNAGGTTGACGGTTTTTCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACC
+
E:E++(/@#52A*8C<!.-8$<&G1+-&C9D=A1*E&,5$&=F8'!/3B)"B+!;82F/(C$0A!B*7:<3(3'1D&:8*'+C8="!B03(;&(*!C-4#>,F#9'7&5A7.!B<C5'E($':$AF3>(E0:*/--,B!1F!(+@/0CEC.5G'#<A8@%32-9&:1'%716FCHD+?+HB;)3D,8H8&$9;@2'$3-=9.4E?H%&.+-+90-EH8$-()F5'@D"5',1%007F68?'!0;4!4)G3G)4G;<&07)F?
@r651
GAAACCTAACATTGATTCAGGTTCAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCAATCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGA
+
;%#GG1*1;!=F4-('FED"5F(C86*?9G/@D)(50G*1@2$@8F6/<B'!52%=#'2:+?GEA3"'4C<G'3?94.:*F08:"F7/.3:747$+C#@.H:&@!@-;="E0="!.!
@r652
GCACATCGTTGCGTCNATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTAC
+
7!!-+4F>G)B(G45$:A0'+%-(<#;?=;8F-E/"D=-9'C.5#1=.'=7!:*>):1;HH3F3
@r653
TCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCCTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACG
+
EG!*H/-/BC:81F+*?6+>G12@+'H!C,?+.A"B<;@+&0<42D6:9(D)/D(EE/8EG=%,"F;*2,6E&927&:%E9"H;8&F$!-96>1H+:/7%%89#5EC-$(FDA$F@#8@8A*;'=:A(D#!:=/*&.$D@76-7@B4G"!-3.%>2CC)*B.#C1%
@r654
GCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTT
+
$)F4F.?4E%$;*C4G3#0BFG/,5795!>23BAB%9--"$4,@<H<->6'/@"=2/6-(?BD-F+;4##+A*1$;<6D0+*?;;>CBD$6.@'
@r655
GGTAAAACAACAACTTTGAATGGAATGATTGGTATCACCAACCCAGAAA
+
5283!3+3#;C-(+*0>--,ED1"&:D)*E+780G9176",3(E+*#1-
@r656
NACCTCTGTCAGGTCGATTTCCCAGAGCACCACACTGGCCGACTGCTCCGCACGGGTGCATTCATTC
+
$&,%C"%@<-A9,,B*/,#B;=C-3>D-E@GG#(,:-6C.-8(8!0-+=>A-)GB3C*&9D>#$-74
@r657
CCGTTGTCAGCGGCACAGCCGGGCGATNTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAG
+
.3!/>&;C<8BD(!%:50>,F*F3<!'56"D8C$-!$:+';EB,+39!%'#.C(+,*&"&(1G/=+@=GF5:)5=@HH",G,,?,$H>:F595DC8;>C,::,#4<+%B#<&$=/C.9H?'9<G9C?@G%"#
@r658
TTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGA
+
H=*E)8C+"(-93!-,!D-7*F-GG%$.#=$+F48>6+#F
@r659
GAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGNTAGNCGATCTGGTTGTTGATTTGA
+
7=0G?E.)2@(F+HA6$<B5D"46?A(A42,=+<'0?203?68>'(=FH5&-+@/2=H$2>'0/F1:/13),00)F(6>/@H;"&B':7+G<
@r660
CCNGTGGTNCNGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGNAGGCNGAAATGCAGGGTGANATTGTGGCGCTGGTCGACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGNGAT
+
&*'$%*"!'+'+"()'#)'%!++%)%'!%%#!)#+$"$&+!%'((%$(+)"%')(#'!&'(##!'"$)&&&$#(#)($+#(+)%%$#'$$#()($'*&'%"(%*!"*))#'(#!"$%(&+!$##")$)#+&(!$'$'%$'$*+&(&(+
@r661
TACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACT
+
C3B4&A/%C,223;A=,:.B-@'D?8+H*=)%6)5(F:06</=)2
@r662
TAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCANCTCCTGCGC
+
-+'F7+5-.B$"-=C;"$:#/0++!,EFD4!8#B=.B@*8HB'B:=0$%C71D!(!,:#9.$)F,/36;#")?34*&
@r663
CCCGCCGCCTGAAANAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCAT
+
42&6$F.2922H2,7%/93,(?4*9/!0AG!/)%1(09/2E.,<3+D)F4.4=H=%G<>C4)H
@r664
GTTGGCTCTGTCACAGACTAAATAGTTTGATTGATTAGCAGTTATGGTGATCAGTCAA
+
>4:&(>AH62#@&-2@4/F@-";>0#C98;%<++-;00#/%-;/$H;%"/F"F9=F&*
@r665
CCTGACAAACACAGACTGGATNTACGGGGTGGATCTATGAAAAACATCGCCGCACAGA
+
+"""$$'!+)#!*(#')!!&++)++$%+&(&$"$")%'''#*%$"%!&"$")&)%)%#
@r666
TTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCAT
+
7!FCD=8C&)%)0%-#H=9!=D7)45$-BGC8--A$?#5F=.4.A'<;3#C9G
@r667
NNGAAGCANCAGNGGNGNNNACTGAANCATNGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATC
+
#!!!$')*!&$%"'"#*!"&''(%(*$($$%$+(+*#!'*%#))$%(&#!'*''#"&''''+('))+(!*""%*#&!'*'("+'&#(%!&+!$("(%)(%%!!(!+*+"%(+**$#))+&
@r668
CAGTACNACNGTGCTGGACACTGAGGGGAATACCAACATATCCGGGGTC
+
*&"*'%%("#!!+"+''("!"$!'#(*(&&$"'$(#*$+$%(!%"!#+$
@r669
TGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCNATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATAGTGCAGCAA
+
5853=F64(#$06%0+.$?+CF.E<F(-0<D3D1?$6B$82*&6+2<,1<"22>)#FH5-,.78H>5#(+.:6!":;=G<#28'"8*C(7$49H1@(:!%-HE0,,'(5E7G$:>5@;66B-;08,3@=;:!$A(+%4A-2G;=4D5CA6)!,G66G9*09!!-H2:
@r670
TTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTC
+
C5:(;H0;*F*%#<-6E$%4-BG"F$983#.7?%F2/D.E=&
@r671
GGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGC
+
)9%&;$*,G+3$#=H<4)'9%*2(%@>+)?:D(HEH13"9=?#7E2(@B%F<?.;4#/)80<*".EG84:$(:6053(/%E=G4A8")2&#--DD$%/$><4C6:&73G*'
@r672
CNNCNTCCATNNGCNANTANNCNNNCCCCNCATCACGCANTATNCNANNNCNNNCGNACTCNGNACTTNCNGGCNTNNGN
+
!"#$$$!$""!"""!"!#$"!#""#"#$#"!!$"$##$#"!!"!#$$#!$$!!"$$!##"$!"###$$"!#$"#!"!$#$
@r673
TTGCTGAGATTAACATAGTAGTCAATGCTTTCATCTAAGGAAAAAAACATTTCAGGGAGTTGACT
+
9BECD&9"0=D?6),$FCC8/;?3F6..).!B<-&;<,(23">*70%G)G'3/$1H<@@3:E#A9
@r674
AACCATTCTAAAAAATTATAATGGTCAGATAGGATGAGAAGGTCGAACCGTTNNAAAAGCGATGATA
+
'0F1@DD#;3*,%(9>;!AB#A&A2D!,5'>'.?2)""?,A2"87/GB+H@?5*EB2D!1@,791,(
@r675
TNNATCTACGNANNNANNCCNCTTCATTTCGCATAAATCACCAACTCGTTGCCCG
+
*!$%%&$*'&")!#(*&#(("+'"$++$+!()&*"$*$)(%!+!*&'#&$'!"%'
@r676
TGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGG
+
<.C:>D13;,%620/E7;*=(;HE;15%D",01&G/:@.B.F9
@r677
CCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATNTCAGGAGTCCTGAAAGACGGCACA
+
;$#59#)&D9!6618?B?5@/,=;>C:.DA/$4?6'(E?*A&)3-D":B9A?,D5GF34+:!5*<<:5<B-2(!F
@r678
TGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGACACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGAAAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCAC
+
>@.F#;<;2/H-55>E0')(5G;/+;.!EGA3.<HCFG'4))0>#5B74(>F$%*F/?E>D,5(B+/%5(##'7&0*#7A5"/"</&.8/<7;5H#@C6:=76>#G.,H'#%18.#G*3D'",<7%&2*HB)H4$-6,-#AE&+(%:F1,E$E)H>C
@r679
GCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGN
+
';)0%<G%@F342E<4C#("/'.G%%5&0@"A'8-D-;*C>.?!E!4,1,A?$G;9&!23A?*D8!=&
@r680
AGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCNTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTNGANGACGCCATCA
+
7;+@9(@$=4&@9F,4&4&89!2#7"CA2)=>9>#E)8E,A9H8-GD"7324(7D<42(-.<17F/=E+H(G:(E+A9?('=4>A#:&C-G+6/3B<;!CBE.!!9:E3)<;)H*:@.F4D4'?>HF&B$D%CH)@CE"C=/&,.518;#5+H?!:*0*;<(%!@F>"
@r681
AGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGC
+
//#(/77<EFE$%&$1/C)2$&D:C44<<1+.'E,"'.'10;B1$2/,GHE5*8$<'><29#
@r682
CATCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCGTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATA
+
''.B'!?8"?2CA&8+&2?(D+"D<2.3D*B59/8)A#-.":3$&/DG:#<,3%1+!+DG)7H("9"C#$FA4F";/E'H7";9/0)6(@>0/##:B69!#<%58;H<%?!8D@>B=<$(6=C+(7H-+HC!.A**F2&9**?@E,$$=G;<9"33='7880!2-+.G(/GC?D7A&7"5.<@H@688#>6"">
@r683
TGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTAAAAAATAATATCCTTGGC
+
G#/@(EED#;/,%D(E/9-7@CG$C:')'<.)44$3'0/A7"7'#67C+A3D,:;'C9"4E30)HA1@4.C4<%DF%6#0<-5H1'-&HD,@,+5=-F".6'5:50F60>2(G,B)&2FG>/C26<;G(DG-+71D$.>
@r684
GCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTNAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCAC
+
(>),;#6/@<$,.=43/1)E+*B$H,0'-2)>$&>.7BBH0/5E&AG7D.E1F*33.->3'@+0,H0*2<H$$3!F0H!+?->34G&4858F338>46F!@+'9;*5/@DED'%4)$0/A2F3(/1@/?&09$H<#846++>2)@CD$+E@&-H>%@:C(@'?$7@1&F'-;&(;+@G:!(1A&@4,FG-8*&:+''<#;!&
@r685
ATATTGAGATAAAGCCAAGGCCAATATCTANGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCC
+
>;7D:4<*2(,.(@36!6GC=5$9/D)=%$D#H>'"0D;./F@#&4?:D?61!<"&C,,@,>CF')<5*>.="2+D'@&G$B:;C,)7@19'<C>FE%)<!!;
@r686
CAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCCTGAGGATGCGTCATCGCCATTGCTCGCCAAATACAAAACCAA
+
8B)6.+!?-)&'*"@-14;60!85@39%;>6#D1;<H>B&%,&$%+$#<%B&<F0=<-2GD'339"<6,*7@A1A,=*(6@'>#."$,<<9;B)06$.!EH+.H,!E89.$9B>8?+?9#940"")4A-@=H&-2
@r687
CTGANNNTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGT
+
)")*$"$$+%%$'#&&#*!*#'+''*$+#&!%('"!&'$(')*$#(*(!))+!&"*%%&&&%+*'&+%
@r688
CTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAG
+
@BG19?56#+A>6G1/@@'A=3>%<,.:<-$/9+0EHC8)C.H10*+*2+2$).C
@r689
TGGATAAACTTCCTGTAATGGTTGCTGTTCCGTACTGACTCNAGCCAGAACTGCTCATCCTTAAACCACTTGTGTGGGC
+
AD;0$4B<!%'7#9.&A0E1"59:D@*6B'(7E89A74B8'>2(CC@5795/3>#G@AG>C?;39>A5?'5H2(650AD
@r690
TNATACNACNNTCTNTNTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTNGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCG
+
()(*)(""#!##%'&)#"+!'&'$($&*"!*"(*&!"(+(!'*'*(*&'%%)(%++&+)'&&'#*"'"'#!(!%+!""+!'&%#$))*+*#'#+&"**)*(+!+!()#"#%)$#)%)+##%"*!(&)
@r691
NGCGTAACCATCATCGAGANCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGNTGTATTTGTCATAATGAC
+
!4G*&*$B-H8-10.=89<A-A6C=*';7H$+=?C2!AE-4;C902.=!H56#.:/EC5!$.?7$+*)F#G)9G)HE90)3,;(4&0CDH78/$FC
@r692
GGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGAGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATNCCTCGTTTTAGGTGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCNAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTAT
+
>8B4"&"?:7?-A<!+8H63E1C'"0)#.1>%B#C+;:(<5&5652?9%G4;4C2*C526,)C<2=$5*D>F260A:C'=C;B1%99F?+@2-2<5GD(8!D38>$D2467*%8F;>%/+>0&-*$,-;)$@0+8:(85&B?$C#C=---$4=)B-(;E'H,"AHC9'E.129/G!35>,0;30*=F>##:0"A3!9)CG:39C73((-9;&+D04H9((#):5*>)!'F-,&<0D10D1+:"B&,+*;8)/C+6.!GF.8<"C%3'A7*--(45/?5,&7:<#=?-#C!82=+$G"3*"/<6+.!:&?G0E2?:
@r693
CACCACCGTGACACCNGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTNCAGCAGCACGCTTTT
+
,#AA2"<&=/3!;$<:-/C?$5>8&**%:-F-*F'>2.*F4B%?*@;/>9D?E9$&?2'F1#DB6;FH4/18$D7
@r694
CGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTT
+
C;8@.8*.27AH6;1&=#&4"/-25:!6,&2A<5-EB48=<%#'(738G278>#%3:>7G;,;3=,A/-:7=)1=>"=E<%8(!>@E(<CA.-<>:>"2&>HB$&66>=;3-@'".'@2G-&@=!)/33@):6C?A;#@+9H2,23&54.7,"+/&%)>>&1A!D!B7>)A49(F&,;#C(-$152;!
@r695
ACGGTGTGGCAGCCGAAATNACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGC
+
8;&F6-.7%"7;F*H'D#23B-?%.?33'??%EBE->4#BG-B)$!"/F#!'1E4BG3
@r696
ACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCGACGTATTTTCTGNCCGTACCGCGANTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGA
+
D&>47>1,/3?'H=/&/%.8B&E)HAG*.G$2+"&7#(9(5@H#G-;4!?*CA9<6!>;9E#4)5:3"=E4,CD&&0"/<581>!&&B7F.-%*H@A92#CA!'"D1&A*(B3-54!:?-(:-2.FA04H1?.;/!!/H@5>.=?@>2:+'5;1C##!E?,)'BH;C58:3537'BA895=,<%1+
@r697
AGGACGCTTTCATTNTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATA
+
04!><.,G-#BE54D3C/C&9.F5<6./H9G+:>><(56B+DE/>@4F#)D!-?$!2*)3
@r698
GAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACT
+
D4?H&A0%:5=D+"'*9#*9)!)?A(/3B@8";@&:91!09:1F52,35>);7.H5>7#BB@;F9',/<"B&E%0A
@r699
NATGAAANGGGTATTGGCGGTATATGGAGTTAAAANATGACCATCTACATTAC
+
+(&$*')!"#%'&%#'')'"$''+$!)&)+(+&"#(%&!(!(+*&+&+*$%*!
@r700
GCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCNGATTCGTTCGCGGTTCCAGATTACCTNCTGAT
+
;&(E(B993%/&.8<5G)2?=",CB522(H9=(@G!#/(*!14.G$@->-&EH;@F%D*2"@DG32:B618
@r701
CCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTA
+
B?C>CA58=@)C1+,#&/%%%CFH0+66*!3;/-23:*1.
@r702
GCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGT
+
8<H<.69#H$>2&28C9"@@5C>>D('G-H;GH3&5+&,-F<$HG%7$,*C1F+-62337+F,#;7@B7G(>51C1''1*6H2F!D5D::=/$04%2=#GD8G,
@r703
NACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGG
+
"+(#(%!%+'#*!((*$''("%&%('"&!$(*"++%%%"!)&$!&))'(*"!"'&%%'*(&&$$$%*()$"!!!#!)''&"*%"!!%$$"'"("#((+)#%')"$&(*
@r704
ATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCNTCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCTACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATG
+
*,7B?"*BG$8.<3)0381/FC&2-'@:+&(=HF84DA::?%8,:>,&$4E@:-,+#B+H23>"<D:('&37E.4<CG0H6CC:4(:5D,;9!$<:1+53&)9D6%@%3,+G$0?!6'90"3':6/>'!#6-86G(2DF8A1%#+F"(E0=?%=G778369E3("E*&D=B)*9E2G/=!E6#/;/B-?'8*HG:,$%G*3&'C%F)$H+4"C/1A>6CG0?'C8D@**!F5"C"?1B"%*2E%G-<1D67+72A%E5H'7.8$9$+./61B8"BF">?82/%DF=&F*!+/(CF
@r705
GTGCTCATCTTTCCTTCCCNTTCNTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCC
+
2EC2B+G<A@7*>;3AH2D!&-(?1B,6;@5%(H)14&G%9G=7>">=5920GAF&FH&*@@<6*-AA$#4<&,0?0D3EC6?H:5,G0@%
@r706
TGCNNGNNCGGCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATNGCNGAGTACATCCCACGCCTT
+
#()#!((")&$+'(!%+#&*!%"%$*)!!(!%"+#+&$""$$*%!")("#'$!'+'"$)%*')!!&$&&&+!'%*+%*&**$*
@r707
GTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTC
+
=+03!)'D%-<GG44H1.)0'%&>",?29'##5.'9#!9.;CF)-F(7#-!8.@3071#
@r708
TCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGNACGTAGCCAG
+
2-3G@>:-?%>B>6$4+30C36>*E*%@:%%7D7F:/>F1A=*!!4G9.,-*10):$DBF2%?FE!*!<$(3'+"23!=
@r709
AAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATA
+
.75+9>/!A1'34(!'(?"5"=0A".4F$%G-.GF88/"<6?,B).$8)+;C!&H;/BC>A@)%/+&,,+;;)#"0(;-B$.6'?E9*C>!)&>#4C%>A(<'%04$>*-9E6@9H
@r710
TGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCCCCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATG
+
.<!G"@;!C(=223D:"3B)239103"$D):380&CH;"EF(6#";(';?)9D&10,+;)-%B:?22?+=<H!:&79@0@B723"89:5-:#>H&?.B@68C+*6,,*AB%;1H8B=C+3F-F=H18'(*;!6>?7DE895/5HG2;."-C#6/?CF96C'"*A1+'E8<7+6$3"-.7<=B%0E
@r711
CGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTNACGCC
+
115.2=@?<BC?$?C776B1"1$2B92;A29B7%#:/(;;',944H>C
@r712
TNTNTTANTACGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTG
+
!"(")*!!(+#!)($)!')'*"+%)+("#'+##)%(*'&+*!#%"*'&("&($%*+('"#&)'#!##"'+*($#*'&)"'%#&&'++%##'"")))"%))%)%$#)+$"%*(&*&)%'*)!"&)(%*!
@r713
NGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAANAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTACCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGNGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACNGCCACTTCCGTGTCTNACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGNCATGACACAGCGACGC
+
);8*5&9!#8=''./)DC$2GC$FC0HD8E6898C17)2%"0#*@'5>"F%C*+9GD#'2,)D0*4G.G?,%02.E2$36=7"?&E<!3$#5(D&2!"?,)67#(2:4D1$48B"CH;5*&4F27&:>5C&@3#/:#",#D1&G1D)?1*AA9,78H*,A0!;AHC,2*C5.."0.E3)#==($+<B>B52"4;6617DC.A&5G#5H3+7(%A>H/=!$?6"C10)H2/-.60&9G6:#/H=9D.#<6E<<#+.C<;%)
@r714
ATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAAAGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGT
+
A#2D0@H/G9'?BB5E088>E:<9F.2&5#<4'C)E()<./;,!#(@FHH7E<F:22#=5:;>8&GE<FG1"FG)"%(G&9<G3D$76"C%7!<2E*@>=<DA!*D:'C!5!,8A-#8+
@r715
AGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCTGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCNTCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCT
+
4C0>="E$;0=;&63-7(2>/D$64"/&#%2#'0:-1DA,02=G)'#07+9=E()<GAG%<1&>561!%&)7H$EEC7@!%G-HGF!1")GDAFF)8-+(#HDD0=HA(4(4:2=;:!+D=7.7A<&BC+$!E&,?&<&G5D."D'<E-,B287@E+B'!;8)DH$,&H9.DC6F(!47"@!87.8ABE>@=#G<42%0'@"*1/:>D7/.$'A8&113F6C8:F9FH''&.EC)7@(30>42#-)%#"$A+1(73;&33>2<2"/G4D7H;5,H5%@D!+3D*>:!";4C<%FF;0B(+';&?E;1@H?&C,>&71739=@(',5;G9<E
@r716
CAGGAGAATAATGGAAGTTCTATGACTCAATTGTNCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTG
+
C&F);=A06A7"%)8A*"9?G5%:+'F3<<+AD.13;D.E$G4B@:D9!>%GA?F(?H/''=#!H3+"#)F85'7(($C%3)1!&C<*C&D:604?%,&0,(&+H:6B$-B)
@r717
TCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAG
+
5E<&3%&&/GC+>)?*+?:?!"7:)@1$A!?04((&>8:#92EG;:#.H)8+&
@r718
NNACGCCTGTCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTNAAANCAACAACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTGATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGA
+
'!+%$""(&#)#&%%&#'(*(*!(+""&&#+$"&&!$%#&'#$'"$($'+!!+%"(!%*)#()$%)&!+#"&+"%#!'#$&$("(#%"#%(&#%'!(()#%")+$%"!*!%$('%!"$&!'$)#+&+&&#++*"')")%*&!)&!*%(!"#")!'%!&($$+)*('&$#+*)*++)+*"!$!%)"$'&$"*)+!+$(%''))$+''+!$%#(*#!)(+!)
@r719
TGNTTTCCNTTGGTGCTACTGCTGCCGGTTTGTTTTTAACAGTAAACGTCTGTTGAGCACATCCTGTA
+
20!+B?,"5*4='A)1ED6$C8#%>7,D6B32=73*<3,#@G)EE0B>+'1690CG,E5B&873=.):
@r720
ACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACG
+
9.18)//='!9=9!F!-F#<:'B)DH3B(#:"5B:3"81H%
@r721
AATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATAT
+
7#=ACF<.GC,EF3)?C!1D;#%;6&-&6>/#;GC*?%B@:H!-9
@r722
CTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATA
+
:.;7F0)7*7$3G#H(02".H"(G!07:&/$9#+>;H@,C;))-!$29D$).C$,!649.&A5F?8=?;,7'98&7<3:'>0.(:E6('B
@r723
NNAAATGCCCGTTTACCTCCAGGGATTTCATGAAGTTCCG
+
$#;3>&/C'(0./#!H/:.;2/:G$1713GHG/E%96F4?
@r724
TCTACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAG
+
&(#+%(*("$))+&*()!%"")!%$$&*#$('%)'#"'!&!%#!)+"#(++)$&('((!**
@r725
GTTTGTCTTCCTGCCTCCAGTTCGCCGTGCATTCAACATAAAAACTGATAGCA
+
+*&#!"#$&%!##'"+(*(&$(#"#$%)#$$)%$!$'#)&!#*#$"((()*#)
@r726
GCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTG
+
-$2%H90A(.9,50-=.(7BED0526-@<<E,=H!.G9!;D85(/$B8;D)-%)"6'F:21$=(*-H)25<E9*9/.9*16<5D0$'FD$E4+:7*01//G(+*57(A8F<&%<6G
@r727
ATGAAAAATGNCTACGAAGTCCGTGGCGATCTATCGNCTTATTAGT
+
)6!-A"*?E2=,(06A/9GF34)B?+="#A@,@*3?0<E+=.=#,C
@r728
TCATTNGACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATGATAAAAAAGCATTGCTTATCACTTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAAT
+
E!0'.7'!?<3H:D@AC>A:0C55#0*'E*D4:,@$"0H!EB=9:0=<:G1HE$>54+HF2E0(5)25@))H?4.5@<F22(*+/F(>C/(+!"@$/0;A>:%;--8
@r729
GAATCCACTTTTTTAAAGGACGGTTATCACATTCAAAAATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAA
+
*')!%#&+()$!"*'&'#&*'&#')")))"%(#*('!'+&"#(*%)*++("$'$#$)%")&))%#(")"&***$!"*"&$*+(
@r730
ANGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTG
+
*#C<.5=,C"75#='/52)B;-@/0"DF.&8,'=+!*DA./200C#4D;&C408(@A#+B&2A!#',>%-47891-DC1D.<G!/+!G6B-;4;>3/9&;694-
@r731
ACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATAT
+
#83GAAD8A+B5+?#$(7;7'!%,3/C??$$9*;@?B%81+;$%23=?'3A;'"FB9&+;26,=6BDE0672E1$##;*+#$@3..!E-G-D+.B8"3G=C4($2#?.4C13>+'(C,3%(5H->70$D-8
@r732
GTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTAGTCGNCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCNTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTG
+
3*%82#$#09/4?6A3,49(F05)$AB??4EE4.%?*1,7E.24G@-4#?G8D*7,#HGA&D9D2$-DF;(//>&DG&:&4.=401:7&H2?%*,B0(7<%,>3/C<*F%#C9!D*6CD$3?)A9'>D=>:8D@/(.9>9'.9<*%*!(C-%,3H'-+)FEBE3<+6;!%20$".;3<68,7CA(11='(D;")-@(9AB9#@D71F).%,:<))C
@r733
GGAATGATGGAANTGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTAC
+
2)=D=$3+5+C?();=9(+,8;(2:G*05505@/)(74!!-.6-;GA">%18"C,-:-AD<C@6
@r734
NATNNTGNTAACNAAGTNGNNAGNNCGANTTCNNCNNNGCNNCGNN
+
#!$"#$$!"!$""!#""$##$"!"!$"""#$!!#$#$##"!!#!##
@r735
TTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGNTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGTGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAAT
+
6/8<<#?+$=@,>'E;F02A0>#E3:G=)%92F+A(>E=7F-;?(99#&G1(E9*B4>2:'10"9HC%BGC;"9-=H,&=9A>8>9&5;*.!!+;.A&9@/8(?9B<9E+8A7H351B;03:E!A6H5<".='8E(=C&H8)053#(;G+'A*3;'(8$0>'),/8(A-(H1,,?-?=,*H@*81,+-C$%F2%#(*5%!'G801&#=A*H0FA,$*9F18%:'A>*>>E#G."40!'17%;0F6CB$C21C0D4$*(3!'29,.!A:4?$CE4
@r736
AATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTNCCTGCAAACAGTACCGATATTGCACCGCCAGATATT
+
4,H2F0B!4%%;@.G,3<'C45,>*)0D&B::"BGD&8D#G7/%??30A+E"1AD<>70E@D4'+/)"C%$+*B";)=%H(4E
@r737
TTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCA
+
&.#?7%2<5%9H6F7(F)-?:1)E)CDF6-!;>;1'3.HF00-/<353,'"-$C-C3A0%:B>'>(=89,AC*5+0A3=@H9/5?8+-":5-D"
@r738
TCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGNAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCG
+
H5?E+*4ECE<H.780$5!9DAE$#)8%!GD<=&8;/$(4H0).5?C"'E,+)1-/:C47@B)F?"8$H7<C'.FB6=>0$3.'E%<.(DDE"5A2G,E$%74:-*7;0(2;H6-%9
@r739
NTGGCGTGGAGTGCAGGTATACAGANTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAACGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAG
+
$%.+72?-$1?AC@7DA$091!:2F.E65<C*+:E*$G,"3E=%D/@!C180#D'=4(,AG#30<B"@+%.@:%)@2"0:7F+'(2F%E6<.5/6<@F=0,-7<10;$/AB*(F./;"+CH=):09.4)C8E)
@r740
GGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGA
+
%C@)A9&@CD'#G373#F2A/@G9>C+;(-E*D7771;DH-47G3)94%F)3?878+B$:@@>%=;&?%:&5,C>22
@r741
CCGAAGCAGTAAAAGCTCTTGGATTCCAGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCNTGCAGCGTACCGGGATCGATGTGAGCGCTGT
+
53C4D4:A=A>3/&*FG+!46982):=G<F85.44$7E4@6?>#-%H*G:B.@019E+*5"5/6"09%5$&19E98(2@G9#/>2-200,372>74974<!:=2C>(25*/
@r742
NNTNGGNNNCNNGNNANNTACTCNCGACTTTNCANGAAGCGGAANANNCGGTNGNTCNCCNTGAAANCGANTNGNTNNATTATGNGGAATNGANCGNNTCCAG
+
$"!#"##!"##$#$#"$##!#$$"""$!$!$$###$#$$###$$!$#"#""$!$!!#$!$##"#!"!"$"!!!$"""!!!$$"$$""##$"$$"#"!$!"$$"
@r743
GGAAAGAGAGTCNNAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAANGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTAGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTT
+
GH@'':C&1D%&"!7=:A)0!844&;'H(:,>4/1$=7ED&G$:CB-(:EH7(9$:=;=@.B)D&5"8/"5?=2&C87+FG"AA"B=4C,H)%<0*B*7-8;=G=>GB!#B//6(>==#E<G(C-(470BDG*F"C4>?8&E-7C)7869(=7C/.%$-300B3+''9"-EG?5-$/.##(9:,H.<*.&*D10.5<.H,>1/FE)21*FA8$8/'":AFA%943$1F4/#EDC;G@G3.!.%&-6!?8DH:0H=/@!+<9D5E*4;D6:&&!C-%6'%=?<&'(F257*1,E8D8&)>=7F*
@r744
AGTNTCATNNGCCNCTTACCTGTACCTGAATNAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGNGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACT
+
*$&%$)('')''("*!$$+#"'(*!#!!))%#*!!&%&"++#!&%!$$++'(*#%*(&'+&%+(%%!!*$"$&"%#**&$*(*+'%#$$+$'&'!))((&'*&"*+$'(')$*!!#(!%#*##&$)("##%$(!&&*($!+++#')!+&%($$&)#+%#*%""$)+()%)))&"$%($$"+$(#*)'#$(!%*'&!&$!)($"&"%+#+%&%)('')%#"(&"'$"!*
@r745
ACGATTATNGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTATCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGANGCGTCGAAGTGACCAACTAGGCGGAATCGNTA
+
#FF0@EA27784D1/2$<:!'D:&E3<%#F=AB58<.@,*%A-#A02)-C%0D9!+B)@F(3='#&@&D73*;;=+%27A?!+-%.74BG0+"C2&"70E'3*6.)B39+EHC)7/4AE&!?5HH$;+#(AE%.B.8#%B:!3#-027<8-C5H"1$-HE-7B7A+<4&#<8*8!5F)
@r746
GCATCGACCTTCGNGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGNCAGAAACTGAGCGACGGCTGGTATCAGGTACNGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCG
+
3<HF6B3"'5$=B817'<F+1-71>D?08H/,4)"6$$(D,3$=6-.7"#%,7C8G3B(9<.E@;7(+@9$GCDC%*H,.;0EG,*/+0D2D5D,C08BF/%+$B%2%?@)E4<-?%2*-@5)@1<<=2?234F=CD)15>H3)=HA$B!&*F;(!,.*1,9'3'&4D.G)3&F(!G5&.=4,'D7$H.(D>@'C>6H>A&78&<4.7?%&H2%#?4@!GD%F)'2G40/>)C"0*D3*88/*@
@r747
CTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATG
+
216B1+#5$35B"?%C'%<?<78$1F(G=---7D+"7D$$<<7;D9#'48
@r748
CGNCTTACGGTAATCCATTGTACTGCCGGACCACCNACTGT
+
-!C)G.(G(7'GH:;.()+7D4%1D9E8F!&&(2@"#(A5?
@r749
TGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCA
+
)B46>1F=><#/8(/&'5)36A?,01<,:16#BF=2.B7+B&C52D'.9
@r750
AGGTCTTTAACTTTTGCCAGACGCGACCGGTCAACGTCTGAAAGCGGATTCGC
+
D&,?:B=G/D-@43>(/A/:6?$(A+%B&7'6HE*8/1B7><?BA.74E=&5E
@r751
GGATGATTATTTTGTTAACGATGAAGCNCGGTCGCGTTAC
+
+%=/'0):95DGEHE+-$"39B/6"0(&!<+&?%!/1-%6
@r752
TAANNNCNGAGCTCNNTCNACGAGATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCNGAATGCAATAACGGGAGGCGCTG
+
%%&"&"&$#('$$(!!)%%&$(%#+*$&)*&)+%)(!(%*%%(*$(**!!%!'"*')(+%&*+$")""!&!!*')+"&$%)+!*+$+($&()$%&'"**++&'('""+*''$($""#%!!)!'%""%#(%&+'&!(*'$)%%*(+('"*!++"(+'&("("!$%)'%))&""#)#
@r753
CCGTGNAGGTTCTGCTGCATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCNTTGATGCCGGACTGGCTGATGAACTTGT
+
?76B3F@AC>&./#0%9C-?,4%.&!!354:7&!&B!G82"5*<>*EHDH+(6,?H(,5+*32'CCBFH+>2;>25760"7D
@r754
GGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCNTTAACTTTTGCC
+
<56<(/A:C!C$)B%DF21(5%6248B8,H/>"B-E<HD#4>+&'D'B);%(*B9#4+(8''/<G)$-:73C($?>0?1H+0!(A+8!:E9836G3,>1"601F-)-5=!5)?3C?AHB0&9?:EB7=F.<2=G84>8"/)H91<<.
@r755
GAGTCAGAAGCCGTGGCCCGNGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTC
+
&/8?/@-:DD'$G()@;58E0'@D%#-H/996.B+(/728'>")2G"<!A1E:5B%&)88+F$H(<=1,($!-9!<0"%
@r756
CATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATNACGCTGATT
+
+8D561=3'=4!@+*7?F)<!%=(7>"3F5D:2(*76B%1F'217&$G5'>+(BAEFH,$(#(/'+GG=3'@>
@r757
TCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCNCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTNCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCANTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAA
+
CA-#?&,7//BG"87"*(;C/*%GHF77&"@*>2?680#E:6*HHH.$,D&*6.66=&D::0$9(:/"-:<4),F+=>7*47:%+!F*0$9/>+1(3&9%H?&1G/EF73#,"1%3#6#=->=94A$9>$F.7AE#:;-8*),;.2=:/,$FHEF15H@4#&9?)90!G%9D0@2>.06$"00;&B/A@62/0+HG<37#7G$E(/@BFD.(57?7!H*
@r758
TCNGAAGAGCCCACCGTGTTCACCACCACCGTGGTGCTGCTACGTCTGGCTTTCAGCTAAATGGTGCAGTTCTGTACCGNTTTTCCT
+
("%#"#+("%!&(&"*(!'+"&$++*"%(*)*#*+"$)%%&&!)*+&%!*&+)!%%"')!&"("&+*'&++%(*&!$%++($#))&!
@r759
TAGNGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTNGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATC
+
9-D/(5D-762(>8BE5?B/8.;8!D7/.90),3@F/9&($1=-:%-0?(2/+FDE78*(%<(.G12/.*<C2?=?;-&64!CF;F+/.7A2=DH-H$(,44;H?&/<-C>"B));B#5C-8!=?096=:&,+.<@#9$B//.(A4H?A5FE#!%B7/7/293,@>$872?%HE2>
@r760
GGTTAGGCGATCCCTGAACCAGTTAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGNAAGGAGNAAGTGTATGACGGGCANAGAGGCAATTATTCATTACCTGGG
+
+8%$)<$!!*E2A%320#"=,AGG57<9D!!<=36C8/&D8=4@/AH@&;)3B3.,H$G,D(,8$:57HB),-CHAG7)=H7C<9#-!.H@845A33(-%<(?1.;D>224B:$/B)@6/->""%CH'::'0?3A#5.$"2@1F?0*F1"#:E',-=:B2
@r761
TGGGCCCGCAGACAGCTTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACC
+
)?91"'56.-1B@27<$C"&,$3/3D);"C>&12G84DG$H/6$%(#E*&;%DD?C*7)-DCF9=-D=7+"'A/B@<$=;"#@>.:":>%$<3G=95.@"4+D>'--$53=;(4H6.//((??0(8$<%=%9"7+5*5C,A=903=9H*G?E?&F$?$
@r762
TTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATCAATCGCTCTAAAGCT
+
-4?,!%2<6C&4!A4G)(/;,H(5/6H'9#A&A>==F54H=GA)/=#!FB6H/H:@-H--
@r763
GTTCGGTGTACAGGCANTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGNAAAACCANCTCGCAGTA
+
"+%%3#6$%5)*#>:HEHAH5/$D,D@<B7#.H!/C35".32C#@-<A'3$/'>;!7,H+4@F@CBE>2;#H$-=21F7:GA13@)B:.6!07"H)1B.%G48=%9>%?HD/%G4&6!'E=F0?%0%HE9%3"A@C?-#<)=+1
@r764
TAATAATTGCCANTNTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTNTGGTTTAATTTGATGCCCTTTTTCANGGNTGGNATGTGT
+
('*$#&$%'$*)(#%)+*!&'"*%$()%'(+())+(%#()#)%#&#(&)+$$!*$!+'!)#''!'%**%#"!+"+*&'*#'"+#)&#+$$!"$*(&%+)#+**'%*
@r765
CGCGTTACGCGCCACCTCTTCCACCAGCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTGCGTCATGGCACAGAGAAAA
+
<D&9.H!;%0001%#)(HDBD-=#$@:>"05:!68@<@":,1=("->$,-$,D5A+)48F/B'B02E(9>83H952H1F"6&6(=98.
@r766
ACTGTTCCGGATCCGGGAGACCGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGC
+
67>E-&'E-/&G2"))@1)@($H%83>#,#9:C2&H8@08A>4:@=;8H&2D29%HF'D8?H2$$0$-6!(HH.$(H,%;<*</G6<
@r767
TTTNAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAAGCNATACAACATTTGAAGCTCAAGCAGATAAATATATTTTTT
+
(+&)%%"*&)''%%#!!)$*#%('!+"%*##)"#'*"*%$%(#!*(&%++*)!$"$%!$"%*"%(&(%!+&')('*"'!+&*#*'+"$*#%+)*(!)(+)*%"&*&)+$"
@r768
CTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCA
+
A%9F52>((?.)A92F5HB<')&06;!,)A%-8H4C--7+?7E2G6>8>"79A-&GGC=@"&#1$BGE&+%&9)
@r769
GGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCC
+
9)HH/G:9E'.06,81*-@).)+$*.+791F!!#-*F?=7,:BG<()0G&?6:?HA9++3&H5(%E*)C@#C"3FC
@r770
CTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTAGTGGACTGAATTAGTTG
+
8=D>#D799A:"(-66D'+?+=,:#..3F6!1,$+</*(E34)H7,!9$0.D*7C2(<F73&:.H=DD<>8."39!C9>8*49)$.9;
@r771
NTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGTNGAAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGNCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCAGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTNTGCGCCGGAGGACGCTT
+
$'+"*#)()'!(%'"*()&*"(+$$!$'**(*##()&)#"($%$#)')&+"%+"#%&$*++%&#%%#$"'&)%"%('+$'%"(!"%!%$('$&%'++'&%!"$%$%)(+$!'"&)&$(%**&&&+%'%%!('##"+++(!$%(+&&(%&)$++)"'"&&*'$!+)#&&+#(($"$&!%(#"***$"(%$!)##$'*!"$&+%&#')")*&()#+*(#((*'#&%#!$%*+')#&%')!&#%&!*&+()'($($
@r772
CNACANGNGAGGATATCTTCCTTCTCAAANTCTGACAGTTCAGCAAGATATCTGATTCCAGGCT
+
)%"(#$+*(*%##"+'"+)!$(!#$$$"*!)%$+$+$)&!)#&"+'#')!+*&$!'(+#$(*$&
@r773
CGCCACCATTGAGNGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGTAAAGGCTNACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGG
+
*5/A3-1%$7G7H2D<.8BF:C'(E*H-0"G8DD422*=%D0AFC?*E?.$@6(2B4HB92"=)-E,?6%%-1+(,"915'-/9@616&<:;$%D47=F4'=6&!!E@H0H%&G*,;'D2;71G6>8)A-@86G>
@r774
CAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCNGAG
+
@8&0?8"4,4$&!=B.%1D-#63@)'#/AC4H43<*?,*3H=$
@r775
GGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCGGGTGCTGCACCGCTGGC
+
)FGHE>#*3((H7#@D0D"D29B0A3*(/F*>D#!#,"0=CG5E>(02#<5570:68G/
@r776
NTGCTGNGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGANCGTCTGCGCTTTACCTTCGGTGTACAGGCAC
+
*!#)(*'&(%+!%!"$&('%"(('$+%&)++&#*$#)')!&()*#$%#")$#+)%%$'#&'*!&"$"+%')'#&+#%*%&("#%)!%+"(()'!$&%$#
@r777
CNTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGT
+
$"H"0,?$C%/F;;"4-$)2=GCH3!2#*9:)H8'80>+'*%0DC?"G)2B+HA"='6A5F
@r778
ATTGNANNTGTAGGTGCGCAGCCCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGNTCTTTTTGACGCCGTTTTCCACGTACTGTACGGAATAC
+
'#'((%!"#!($$+!*#$%&&&%+%*&''&!((#!$+$((&*"!%!&%)(&(($$%'+*&$()%!!$%#+#$!)#&%($'($+#'"%(#(+!*"*!'+*"!%&"*)$#'
@r779
NACCATTCNGCAGCTNNAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAGTCCGTCGN
+
"'(**&%!"**!!*&!#$'+'+#%%+"!%!&'#"(%!"$'!$#!#!+*$'(!%*#('#$&$)%%)*#!!'&)(!+'(#+%&#%"%**(&!$!$*'(&
@r780
ATGCCNCCGGCCATTTTNCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCA
+
6+'(24@D6<CC$B=6*00.&=-2*CHE160*$'-965!C5D#5460!67(B)5H0?H1#)=,<B@.=-9,*H78A>.'
@r781
GANTTNTGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTANGNTAAGAAAACGCATTAAGATGCAANACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGNAATCTATGGTTTTGTGCGCNGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACNATTCCCNTACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGG
+
#*(%"!+#!#*&''$"!*%%+#&)$(%#&$%!&&'#)+('&+%&')+"#*%)()#!+)!$+#!"&#'+$+%"%""'!&&$$)#!))#+%!(!$+(*(%'%#(#(&$'#**)+*"*#'!&'#*()&*'***!+&'#(#%&!")+%(!(&""$#%$*##'!!%!+&+'!&%"*$#)(!!('(!(('('""+$&'"+#!%&)%(%&")'''+)#"")(#"(!+!#*'!%(!$&&++"!+%)%%)+'*%$)"(
@r782
GATTTAATCAATANAACATTTGAAGATCAAGCAGATAAANATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCGATGGCTTCANTTGGATATCAGAGCTATGGCTC
+
-/GHA3#43$(>*H*D73:FC"6&;:7H(A?D$)52#/FA>C4/@.#(=!6#;9+93H6#"@:/.=#">59"7F?:DE43F8:!H/7@/!G/E*?"/7=7F6/:=D,)9<:)$:9>721@
@r783
GAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGA
+
G6<DG$8CGA1-(*33/'?E+/BC9.93#-+040'0*50,6!>@!+.87'),-4$*'A(H:<$"?7:;$AC9&+($?#>)0@1H!%H'5&:80C9-B:E$&#.G3AGA583'B#"&B%#==,"00E04:96;A?2./0CCD91!8G=G-<$60@A:E?%+A6-#8C+
@r784
ACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCAT
+
4$2;13$(/;9""3-((#F=<2/32?A)+=/#F!A8?/&8:!$#-,";<16F/7-9A"?31*G?,.:!8+?>1H>E&(H,##>H
@r785
TCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGGCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGACGCGCAAAAGTA
+
6H36E)9;*+8#65G%;!B8'6'G7C=*6&1FB+3*0(=+.-E%22/F3C.5,FF377!;:<EDB9@8BB*#:5@50>%B'H18)&=5.F1A2:;CF+B&)3CFB
@r786
CCCCATAGCAGCCATCACATCAGTACCGGAANGAGAGTCAGNAGCCGTGGCCCGTGGTGAGT
+
/</".A?!*E"(.;G>,A&*<@3*G4@:2(;,G!B!:1B'>4*DC#%!6G@96/01@(3H,2
@r787
TTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTAC
+
;41-C=0<1>!-:(4$0EBF'<(%,9:(3E.A<G6AD&=<2*&A7*)*%=(5.9&0:GE6863(:8A84&$9;<<E4<@#87#2<C2?2:5.3"7@3
@r788
AACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGC
+
#7?81;E.F/='1-CCC:/1>/8)'B=@!33B>B#&.&<%-G<+!E0-<&67?7:%*;/>1#)!9,
@r789
AAATCATCGATGTGAAACAGTGCNACCCGAACACGGCACTGNTCGGCGTGCNGGTGGAC
+
+%#'#)*+%%#(###)'"+$("!#*!(&#&)$+)%"$*$(+&)*%"#("&(#&)%&"#&
@r790
CTCCTGTTTCAGCTCGGCCTCACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCACGCTGACATCACGGTTTAGTTGTTCACCCAGCGAGCGGA
+
5-D<+!26+-ABCE"$3(>,504$5<6=C$/B#?H14$%D.5?A1)(-&H94H,)E@!&+.C75D"0+,1!?(;/?-*1E$$#F,@,7:/C;
@r791
NTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTG
+
'7G+5(#$@<1<.='(6DE4?!'AGA76AC)$6A;,'C<31(%3?96
@r792
NACCGTGACCGATGACCATCCTTTTGATCNCCAGATAGTGG
+
!E=/A)<8(C6(&*F&&7"'C13EB"&E#9.?*C;H<B$&(
@r793
CAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGNANTCAGGCTGTCAGCCTTATGCTCGAACTGAC
+
2(,A.+1$'@0'AA/C,9/BE5CG%6<?G9D"8G.<9##C/8=8!:A3$*D1@F3>@.#<.0'GF$F+29:*,09D"80A:E!FGA>38CE#&:%?E:34C2-5.FH42@HG3EGE?2!;G*.#2;2F9
@r794
ATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCT
+
*)+*"()#)$%*(+*"%($)&()"%$#+*'++*&+(%!#$+(#*(''#$
@r795
ATTACGAGGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAANGAAGTCCGTGAAGACGGAAANCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATC
+
5)$B?%!46'>=">?5,4E3GG3=/A=9<6=70"C6(H.@2.)6>,.%-7/=>$A,**AF4)1A7(F/!*@;:@D<!)!<(G'"((<5D,$@'26+<9#%4A+BB<@/06E1"F!H-9>C-E'<E7@B4/2#F@0>>$HF"3%9A&2E#=G)%=@4#6$!E$2##/1,HFE!:46:D01,>:231;+D
@r796
GACTCGGAAGTGCNTTTATCATCTCCATAANACAAAACCCGC
+
%'#+**%"!&+#"("((#$*'"'($'%)#!%+('(*%&%&&%
@r797
CCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAANCATTCAGAGCA
+
=#?C,/;:5?G44+/0'3H)23A@:&%>H>H4!*2;$<H#8CD@FF67#11D/*F<:;
@r798
AGTCCACGCNGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAA
+
'A,7,60;'G54A3+'3E=)DD-95>F?GE,E$B2"F9:26F-E::-494<2!-&=$2EH!>3?0:-5:%F+7@
@r799
GCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATG
+
&A*,E$@'DAD8E?;8596<<;7F@.HGCEB70*C:9+A6=!8*1%12$A7("
@r800
GNTTNTTACAAATNAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTA
+
&!(&!*+%*$!(((+(''"%**$#!)%&+!#!%$'""#))&)$(+&'*'($*&%"%"!#""&)!+$%$%&%!###!$%'%$#
@r801
NTNCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATANAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATC
+
#&%>?(?4=H3(B!-1;'G354>.+%/".5C0=))6C1E*E>5$<E-D)D6/BHDA3H:1373;F680/E%,1FHA+)-50>3F/-06D,6=AB:<8*1B:)*>/!)@BC&5.7%748EE:+?5.%!C<@+5/6,F9AC>C8.G)A@#G,C39(4F5:<'E'8D>5G!=CGA,1E"0:
@r802
GCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGA
+
'/"8G=+G#5/%"%;<.80=$/'?"".1B8@>$;$?A//D!7+)+8B95G/@$G3);$(3;#00@3,$G*@91&"'*BAH;/*=/H8E>*@E%.):)2CD'5(C&1+,B432#2C!C3628H+(3&%@HH+!D9":%/5&/*,).?=FGA(
@r803
TTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTT
+
<@D',$4260"9"C78E7&6(/@?9!0%"18=6BD3,+>HH2:,9.0*0/=4+2#%5
@r804
AGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCANGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCG
+
C/%6!4D"3'7;F9>F=%92>7952*A-;.H$"@::4H:<'(GB(1B5B(#'#A;./E//F(A+"5#&=G8!9C8BH%58%D-4<9&F/;"*2-62A>.-<EE=#H7AA>>=?C+'1B1>((E
@r805
AATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTCCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGC
+
)!'?!+-<-E@>GEAD-B?DB?HF;1B$3%E'#";H#C52&/4;'HG+CGA$7#)#$37'<.?HF<(*0(+:1)'+95A!+$B?@"5$+6"34G?$H,8?"*<750=*H@51D7+*F9F>G5E##@.$/B4#)A>26C%<(@>.A5E/#G@F2)133!DE&<E,49A2?,E4"(E!($2("+B'5##'?=BBG(97;)>>D-&0B3%@)FD;)3&/C57(H45F7>%"B&;D%>6=H!+A-2G@=
@r806
TACTTTGGTAATGACATAAGTCAGATCGGCTGAACTCCANAAGCCCGCA
+
$%)**(+'(#!#!+")*(!**(#**%(&%&!#")**+$#*"!'%%($!(
@r807
GGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGA
+
%CA"83,$-H#>,**'!&#3.%+$154=@7C$>4?GG)+B383?A=
@r808
NGAATGCTGCCAGCAATAGTTTAAAATCACTNGGCGATCTCCGCTTAGAA
+
,FG6'=0FG$B,7A64GF1'$/1#/BG9D6.8%;F';;206,@6!F"3#(
@r809
TTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGANCAAATCTGATTANTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATNAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACA
+
D1B":A<0B@"4G8<7<-;/F(&'47!,==6CGD;+G=C$<;"07+#<8+=.D8F(8@&$@)BE7B//$<>(.+9)C0;0@:=;4"90<0.>E"<E29.F<?6)C-#6))/&B#0+&)&FD)47)C;H$&=FF/(1:",.8$D@A,H1F)C1,54"H"=+:=;5FB)H@'7!"7.G3"*4AFE=8&*26-BE63=>(*45:6#,?H.#&=>3.(B'</(<2(->@$8%,;.!!*5"G;
@r810
AACTGATGCAGGATATCCGGCCGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGANATCGACCTGAC
+
-')3'1!@5?(2!>?F6.-172';10)6A%8#7F1D0F;')<6.=25*"2!:CE74*3//=6/G(,4C%@1DE.D<5!?";56H,1':@%!
@r811
TGGGTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGGATGCTAGATGCNGATNTATTTTAGAGGTGATAAAAT
+
@!E==16D2*/73GHE0E7+631<&$(?D.*F&+>F$%>*@.$2;+/''-3!4"$41DE)9,7;E5:2.C*16G/4
@r812
AGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCT
+
A-%54"#-:0F/45-(>G"+C.-A2A;,(C<0@'$B2E0B&+1+(+18*<DC!4$52$;<8:,*9D@2&1C"+B5$?#-.?;4@>6$B&*?>/8&;G8&0:B
@r813
TNTCAGACCACTTCNTTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCG
+
*+!%"%')#""+$$%#%*$&(#*'++')$(*+"&#'$$)$*!#*&*&&(#$")((%!!+%!"$#!'#%)&'+*('+&''))"
@r814
ACCANGTNTGAGGCGATGTTTTTCATAGATNCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTATGCTGGC
+
%$&*($#"""%+#+&%%)$*!)&*'*"'"%#"+!(!+%!&""%&*"$+&!*'(!$!!*+*#&(")$)$*$")%""+$!(!!"
@r815
CGCATCGGTGCTGTTAACAAGTTCATCNGCCAGTCCGGCATCANTGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCTGTGTCTC
+
%*@.B'8@D.1.("H(!HG!6")HEF>+CBB!=-/C?(:/0G8E7!,=DGE>:)92<B6')E;-C89*?!!@E',8B!#4-B=::G%C/D2F3:))C&$GA?<B4-5CA8*9D2$%'2:D22;8%20)(*6DC:?+D$D",9&#DB945;6>(GG2>,'4DA!A$1)%15F
@r816
TCCCAACCGTTTGGGATGCGACTGCCACGGCCCCGTGATTNCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACNGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCAGGCCATCAAACTGCTNGTTTTCATTGA
+
!"!&%+))(#("+((%)&$'+&$$(&%#"#))"+!!)++"!%$$&)+$$!#!)&)!*#+*$((#&+**!$!'!("''%"*($)$("##$'%&&*!%#&&*)++'$$'#++&("%!+#$"'*%$)%)**)&$#)&*$*%#%'')#&%!)!"*"+$!%'('())'$'%#!(&$#$&#*+#$*'($+&("++#""*&&%%
@r817
TCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCG
+
/3G$/>2=C.'.!,)-3!;/&:E.5HC+$!5(8F=&E*+$0?G7,##+*+&89!AE9"E<3GD4@)%)+=H2H3A>2$B<-(%&A;3C@:?F!A?!1+"B.20CE24-':-,:'-8H#E=":<(GD24+F6A!A)C-E&6!8/=0F@+**0G.@3(:**E(7<6C)F";65H1.1?"!
@r818
TGTGACGATGCTAATCCCAAACCTTACCCAACCNACCTGGTCACGNACTNTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCC
+
*:EF=C'&(&8<E/8==8"F,B=3#"(B/'+B"<5G17<$(%&$4)/$#/&("G."&<*8,6,0>:<(/37+5<4F)#/#9*#5?#
@r819
NTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGT
+
&H>F=D&44$#!5<6%H5;=?-A0*6!.:-#3,434A!CFA
@r820
NACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGG
+
+F5,;4<&B-=/.=8""D-FB.8A21A3"D&<+D+5,+26>',6
@r821
GTTTCTTGAAGGTAAACTCATCACCCCCTTGTCTGGCTATGCAGAAATCACCTGGCCC
+
*?)#G5$G!;(B41@=@?'>"GGB#'CA#*A#1B?A@(@!#A+DAFF8:+9C7.26&*
@r822
CGCAATGAGGCACNCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTG
+
@:;!(8*/2:EB')G*@1#>4*F@D(F@-7(+B3*$FG)+0EH.1'1/A%(BG,1F*9/:4G4<"9
@r823
GTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTNAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAA
+
5986AB@6/BEB8,/6>5+.#G8G6"9D9;9A<*75$C>?%:6'D8F(+?F8":<@;0F(6<HE.4697E=%,+4A3CF3482,1:9B50=G5#<A)C3$8/@??@7("+)
@r824
CCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATT
+
*BF%<"0!<%$&94FA7?%6@!@F42E<!,$/3C02:2$C?H+B0A#*F;'#
@r825
CTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCG
+
83."&6,,HCA>)/&ED;#*?@&?$D'8)@8A63BE)9?#?0&7*A9)AD&E)4=9;&3-!>3AC9><50E12&(#HF%=##2;403G+E/>C"E=$
@r826
CCNCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAG
+
>*5#)2.C5*4373=2-#8B9>CB(6E1#(>'-82%@;)13'2G8>0H.D$
@r827
CTGGCACCACGTCAGTAACGNCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTNGATTGA
+
G<<1.C='5/34/.(HH;$@&%;)!6,H!HH8*2!F@>;"F8>?9>!'-";B>,?0+?E
@r828
TNANNNNTTTTACATNNAGGATCTTCNCNACNNTCAGAGGTGGGCGCGTCACTACCAGCAGCTCGCCCGTGGAGAGAAAGAGGCAGAACTGGCAGA
+
#'!%!&#$"'"'$)($$*'))!$(!*"#!&"$!+%!*#%+%$%+("'"'%+())*+"!#!!))&'("&'&($+(*"("*+!$+''#)'")$&'+"$
@r829
AAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTNTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGA
+
BF*-/41C=%G=//ED'+C886.;+3",6E+ED1B>?5?5<+%E(7-E!G0($,E4-,3HA>?5!.6?,GE0#7@5)'/>8'C(%=2(=7D03@CA26.14"701-0G>G89>-987!;%;?E4C;!C2G!,#!D->!!#-0)/;:?=3>!=&3:363*@<".3E??!;H&E)4-26-HC!A(0'0G2B=!*D!ADB2=C?&073D:'D$E7;D:2<G/A=<!+.B3;75&4
@r830
CAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGNCTGATTTCCGTA
+
*F0)F3*?/-3%-<C7;5#.A%A!$8!5:*HA@::;+#-,D&6*G=@"D&HAC?>"&'97C),+<F'
@r831
NCNCNCGTNTTATATCCGGGTGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTG
+
('"%!*('(($'(&))(*"&++("'#+++"!#)(&++**%')%!+&(+)+*#&!(&"&
@r832
CCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACAT
+
9)%G(3FB$<H+*D/%).!5:G*GFGE%0!5FD3>#9G<-;'5)9>/(A73'=6)8!8"!2'D>7<4.50DB>&5A-8&B8%C;3+9)"/$?=*5>C)!"B7&0::BDCA4=G%1$2=*A*
@r833
TGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGA
+
CF6,#)G991)'(((=A:4%&(H5;(21.%HFAD'+1C=*7@59E#B2+G6B')%E81"?%""2()68.:!B@0HC-G,/-",83-D&*;/7@C-#E4>+:C29+5(-!=?#/,D#H+;4<&=60F2B@6'4&'%(-?51".1,,:$)2#"=A3
@r834
GTGCCACGACCGTGACCAGTGCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATN
+
@,/+'(0<29D-"?*##.8>(C-"%"@6>7FE!(.;+/&.9#F%5>C?'8"=@"(%=!H!'7;B2%88.*
@r835
CGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTG
+
BH0B(<!DEA"/CDC63/0%*+>:6B81-E.*70@5#*/.'DA*)E=.E8@A1A5((@C#GHG",H.&H1G/!'9<-%%08&<6G("26*;@.E/.3'
@r836
GGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAA
+
F(*-"3):#*(B/BH-6:=$/%@"7?0@C2C1:8B*,;F4/!+H!:,==2#!#0&"75F!B/D;5??D1#0H<"$57*/B?D.%1/".G5
@r837
TAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTAT
+
3/F03F;@">A+=(C!0@+@6.=3&9,5C8>H@D%BA-<F19="#<3>)8,$F;"+B1-##=9B+/#
@r838
NCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGAC
+
!CC7%;":C@(,?$8<0>'G9B&#;$=8;/H/$&=CF>1>+7!>:AB+H@G5;=3E&$'$>=B?'"7"F4@#8#:D!9F/(5<2>(#/#>%C)-B..H&#?+'39C4D!0H%";49%GD%47($G)8;<&E636+DB?'-#/+1C700$9,6E-G>0*0/
@r839
AATNCTTTANNNCANAANNANTANNNTNCCTNNNNAGCANCNNTGNTGNANNNCNTANTNCATGCCANCNGANNNGAAGCA
+
#!#$$!!""$#$$"#"$"!$!$##$!$!!###"!"#$"$"$!!""#!$!!!#!"!$#!$#!"$!!$##""#""!#!$$$$"
@r840
ATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGAC
+
5=!-:!$,%"F$D)%$??A');81D&#;6+:3AC0.=)HA-?#?43($!@>E1H-'F@F+'+CHCGG(;*0%9+
@r841
GATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATG
+
4-D(,(@>=>1/C<"E.>C%.E%@F?@?D796$6@:B,$1/$4#>61*=?-6572)(6/'98&*4D97+>H4%63E"@3+@"=5,8"E;A',!)'ECG@,=7%!3@41&3,5F:F-66;/?04
@r842
GTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTCACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGC
+
,ED%F,<?44GDB*?&1:1=%CC*3>6?0(:#11GA/<>-7?C>9F6!C!G0H9AD570.(>06!.568;'+C(6=:7-B@(%E#)"4)36)3GA>439+3=0"56:6/2))>@60@'@>CG'?;5'D72>1DF**B6-0"@5CF(:)?1.F=245%-:B9/%(&9G;>7>/D("H4/80H/;9@8:G?8=,H&4D6:H8:3)@"+C+;=>1<
@r843
CAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCAT
+
;$9!=*-;6;1A:E"10F&/4!493E2%;/)%8"#:F#3799>B..H+9<?B=7+,:6HB
@r844
ACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGCATGACATCCCGGCAAGCATGGCACGCNAGTCGG
+
!#'+'$(#!'++)&#)(&+)&")"!+'!(#(%'$#!"!##!**")"!"(*)(%$($)&'*%!&#&+%"')*)"+!$"+()#!'+$'$$%&$!))++%%#*(&'(+&"++**'&"+!+'((
@r845
GTNGANTNCTCNAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTANATTTCAGCCGTGACGCT
+
)&%#)%*!+(('%+&#)*)%")%'++'#&&%&!(&()+)"'"!&$'+$#'(+)%('!%&&%#&%)!"&("*+*"*
@r846
CCCGCCCGTCAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCGGCACGGGCCGGAGTGACTGTCACCGCA
+
EF1!:(6?5,+C=-1BB,%=">$69#+%!/5!7#6%.3.$/%D!*G9;:>-'A+&?.8E0H#(C91F5=1D)/*E!-6@:;7F!=0#)(F-3;>G(2,'<6<D
@r847
GGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATC
+
292#HC(1,4;*;!F-)57?@(@&$:9D,1$D3:416-G@0C5:HC
@r848
GCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCNACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGA
+
*('&&$+"*+*)*(#"$!#!'%%)&&'*'+")(&#)+("$'#'*'!''("$#(+'(&$)*"#*"&#'"&)'#&&"!+%*&)"#&$(("#&'('!(+%#''"+(#&#!#+&(+(+%$()$)""%
@r849
ACNNAATGGANTTTTCNGGCAGCNGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATNACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGAAAGCAGTT
+
$#&($$)'$%&'#')''$$*')("+$*&+!%*#"+*$'*#(+#&'!#)%!$""%!#(($%#'(#+%)'&")$!%#'!#&#!))**&%(*$*&'+#("*$'$%&)#&++"%&%!%%+!#+"&+*")'&$!)&#%$$#&$"&#'+%''!+%%!*
@r850
NNCNTTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAA
+
#)*#+*''+")$!$&$%"$!%#&%#*%!"*'%#%&&%!*+!#!%+))"%"$
@r851
AAGNCAGNNTCAGGGNNNTTTTTGGTTGTGGTTACCCATCTCTCCGCATCACNGTTTGGTAAAGCTTCTA
+
"%#)%(&!#('*$)$#!$'+#+'&(+((!&&&(#%+(++"!*%$""%(!!%%(%((*$$)")"*+!!#(*
@r852
NNNCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTC
+
%#"(((+&++)$&"$&#%+$)#$&)$$*$)&(+*))'&!+'#"#&
@r853
AGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTT
+
?4$%'?(+".@A--%3$2%G09>1:7/CE?D(D4$C2-CBH-#G)>-9@10A
@r854
CTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTT
+
'?>2:(#F>':)6G!=@#B!&&D?*,)D2,%G;(-&(30,0)4;$&;G$>8G:5:?@55
@r855
TTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGTTAACATCTGGA
+
?1H5"!=C,,(3H0&/"(D&.=#/1E?B8F<G$.!,?!?;5%$;=3#E>
@r856
NTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGAGCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCC
+
#8@1)%&5,6+EF2'5<EEC%9;1#B,)#<F;.22((<90/2,'127;6=E@59:@EH&/+$**C:?$2**%!=<"6"40,0H=*#35$1AE7%F(@72>.;H9+H;
@r857
NGGTTCCCATACCGTATAACCATTTGGCTGTCCANGCTCCGGGTTGATATCAACCTGCANTACGGTGAGCGGTATATCCCG
+
"0!C)4B6'1?,F;.'$#E50<0>,==6BH/=7!D;81$B>H%4%:7(?4C8(-9B(<"&$*;HG%/H":%:.5C!;4<'8
@r858
NCTANAGCANNATNGGNNGCCTGTGCGGCTTTTTTTACGGGATTTTTNTATGTCGATGTACAC
+
!*"!"*$'("%&"'$*!)+#'$)+*!+)!")'%!)")!%$&*'$!)&(+"&$#&+*%*&'))'
@r859
TGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATNATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGC
+
C@5@".&!3C4#6+5>*4<403F=-?,4?83@2D+$!G)&==H'<);(BE3C?-7G*F3B7%>5!83.5>F2&BHF+>4A9?;D0(&/HC:D!F$->60B70)H6E.*=$/#';$-?<(3$,8;&(4C"45.1"G:?&@2!=-!*H;7CFCF)@>"H6<F=*,ED8E+7C.*>'/08$#E617D>:"4$75!C+!480%-E$(85.2
@r860
NCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAG
+
/F"<-;E"HA2>5-;01?,&3&01+7=3/B,-%.7*)'('="++5E:
@r861
GGCACGGCAGCTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAANAGCCGCGAC
+
=6'%9#5C6H@52!?4=*31703$7-@=/-9?54@0E*1),7:&44;AE&#B@<//"0*">2C!2'G(1'A5-%;G(?%',"B?<$5$F+C
@r862
TTGCAACAGGCTGCCAGCGATCCGATGGTGGANGGCATTCTG
+
"@"74=H,-/"),:5D*/A!9,2HD,+E#&1%)/)H'D*!/!
@r863
TGGCCAGCAGANGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAANAAGNAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTG
+
F'+C"B.*3(1&2E!,G%*%(28H+;7)79:034"'#5;G8E%+0,:):)D*%)51<;.;8!%-$<7@3389H%E$C6*H5&>=A%18#?<+7F)$-&C3,:7G24+6<B!@;40,BA9-A.0')G.0AB?!-70,)!705#)8EE$5()"'(@!.,E+0!H45-=&B&"$354)(&,@!4.
@r864
ACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATC
+
5!/BH3:&=;5&'+,-<@E;?F@!3D'<&"<;E.:&:"=?C4H)"E?%A4545)=4"AH!*(A
@r865
CATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTAC
+
>B2ABF0G.G)8+197""'4#*";E0,>E&3"!-H4E&C<#(9D*-@+D<%%**@.2HB@B&2&9E2E95A;<4"(C/G>CAC9?/AG+:5E#'<,EC>?<6'"%'*"G/+33+5!A26?2*,E>?<,/D4:A?20!*E271".&>!&A:=#7:'5)5.*G&B24*,#.94836B$$80.;$*6
@r866
CTGNCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTG
+
)$*!)+""''$""+")(+$(()&+(%%%#$''*+&'%(''$(%%"&""$$$&+!$#'&(*"'
@r867
NCGGCGGCAGAANATTCTGCCAGGGCGGCAAAAACGTCCG
+
"*+(&)$)(&*&+*$%$")$*)))')"#)!*)+(!!#'$*
@r868
CNGGATCGNNGCNTNAGCNNNNNNNANNNCCNGCNNNNNCCGNNNNNATTCNTGGCANGNGNAGAGNGNNTGCNNGNNNATGGNNNNCNGANTNNAATTNCNTNNTNTNCNTGNNATGGANANNTNNANNNCGGCGNNNGACNNNNNGNCGNTGTNGAATNNNNGNNGNNNTGTNANNNNCNNGGCNAANNTTANANATCAGNNNAATCNNNCCACGCNANCGNNGNANNNGGCTNGNTNNGCAAGGCNNCTATCNNCNGANTANNANNNCNTNCAANNNANNNGGTNGGGCCNGANNGATAGGGAGTTNGAACNNNANNANACNGANNNGNNACTGTTNTAAGANTNTGNCGCTNCTTNGCATCCNNNNAATNNNGTCNCTCGANGNTANACNGNGNNGNGNCNANCTGNNNNNCTNNNNN
+
$$$$#!!$$!$"!!"$#$#"#"$#!###!"!"$#!#"#"!#$""""!$"$#$$""##!#"#$"$#$""""$##"!$!#$$"$"$!"$!"!!!#!!###""$!"!!!"$!##$"$"#"$#$!""$#!#!#!!!"#""$"#$$!$"#"##!"$#$##"$"$!""$$#"$#"#"!""!#!!!$#$!"$!!#$!#!"$!"##$###"""$#"#!!!!#!#$#""!!$$"###!#!#!""!$"##!""$!!##!!$!"!!#"!#"$""$"#$!"!$"""!#!!!$$!"#$#!!##"!"#"$$"!$##"$$$"$##$$$!##"$"$"!"#$$$#!"$"#!!#$!$!#!"!$$$!$$#!$#$!!#"$#$#!"$##!$"$$$"#$$#!!"#"##""!"##"$"!$""!!"!"!"#$$$$!$!!"!#"$"#
@r869
GACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATC
+
6>D.+%)1D)01?G8CB-D"1$B:!2(-8*-,:2"/A1@=71)(@49-D*<<?C;<<3C+#F".G*)/$G4+/(9A:@'$&!H3G@'E&"366.(?E(:=
@r870
TGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGA
+
1(,(($4:;1!"F-,F"2E."7$#,-CD/+8%&/0?;.(95%CH+D).0:'
@r871
ACTGTACCGNTATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGG
+
;6+:"#D#,6$<39:%(41')C66=*57.BC1%6!@.F,%*="5EE855)H7:=9$,@=&86<:&&
@r872
AGGTGACGNTTAATTCTATGCCCAGCACGAACATTCATGCTTTT
+
*)+)#!+)!&+&%!$)%!"+(&+*+($%"'("!*%++)(+#%&)
@r873
TGNNTNNGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGNGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTC
+
%)!"'#!$*(**)+(*)%+$+&$"%$#)#&)'&+&&!"$(%!&#$%%"'$%)"*%%*!'+#"))+'($%&''%!#%+%)'*#+*&&"&$%"*+'#$!%*#%$*$*$"$#
@r874
TTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGTGTT
+
1>.'?<).BA1?'*4)<6)*A@,;*/%*F7;$!;.5?$9>)CBD>A54(
@r875
GCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTT
+
HHF0'E;!!/5*DG5E4,)C@$):A=%/2:3(60.,BE48.3&72+;1*4A*!2;0A:%+.-0(=EB>-1FF$>8
@r876
GGTNNNTAGTCTCGNTCANCTTTNTGANTGGTNCNANTNTNGGTNNTTTNTNCTATCCNNCTNNAGNTANNANNNGNTNCCCACNNNCGNAAGCNGCACTNNNTNTTNGNNNNN
+
"#"!!"#""$!"!""$!"#$$$##"#$"!!"$!##!$!"$$##$!!##!""!"!!###!"""!$!##!$#"!$!##"#!#"$##""!$$#$"""$$$"!""#"!$""!#$#"##
@r877
GTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTNTAAACGCACCGCCATTANATCTGCCGCGAANGTACGCCATTGCAA
+
:($?!#!:=FG@;C/$F02",&.H&3:5@H&-'#+>C(-@G;6%.>/-83&0?<"3",5>+?916@:&'$BF2+!@017-A@)C%.#+4C!/>E<&.B#.*,CG91":"#
@r878
AGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATANTTCANTCCATTTACTATGTTATGTTCTGAGGGGA
+
A<4D7"F@@H5'GA.'%G#E!)9$>#75?<E+5=$G4;FH#3#=E:E1#;"&AG?2C?2>D,G67-%""?-?5*.>4CEHD*2,:76E?)C8@C,7G%6BA3"%C91F*A.0*5=',GCF23+'3*($'?('BD7.H?=8"HB7)!7C8G:9;8=?4
@r879
ATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCG
+
+#"'#!(!!+&)!+$$%#")&#$"%!)$%!$#!+$+"")'#'*!#*"*'
@r880
ANANTNCNTNGAATACNNCGTCAAAAANAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGNGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTA
+
*#(%'*$"%%%(**''#"+(%#+(*(+%$!+$*"#%#)%'')%%'&%%((#"$'(!&%"(!$+"&!&$$$!&#'")#%('+)"+*&%+'*++#(&&'*#*$%'$!#&&#*'(**"$$%"!*$'#+&$#'&&($#+%+%)"%"#$'*)
@r881
GCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATNAGGT
+
C>-9@A!8E2.&"@:!**$-8</EG;5&AB8D&H.GE-3@(91$2D85":EHF/>(<4-519D(#E%.)5F=@80<@;=.++.&&.D2&AD=86A,9610$#$B
@r882
GCACAACCCAAACTGAGCCGTAGCAACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGG
+
=+6A9F7=!4FA*%';6+9;9)%'>3H10*C394(6F@G"!,,(?!!=@)H;#%;')?>F-1ED:F@BA-BB6;99A0D3/CB#:3>":D+D6=747D
@r883
NTGGGTGTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGAC
+
"'$*+(#%$$&(+"*'+'**"'%&#()"*'('*$!'(+'!*&#'$#)**!%)&!()+*$")!+(+&%)!$
@r884
CGGGAAATACTGATGCGCAGCGCCGNCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTNCGTCG
+
(>=BBAHF=EA1+D'E&+0@/E5DF?"2,1;@9/--:'4D9.$1+E,?13C6-7(,;.%78*A-3
@r885
GACTAGCGATAACTTTCCCCACAACGGAACTACTCTCATTGCATGGGATCANTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGAAATCACCTGGCGCAACAGCCTGCTCCGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGAGCGGTCATGGAATTACCTTC
+
'"-<,#=0$#1B0"E1,C8A17+/A*(6C3*6C++<=6&H'B5/C>.-(?35DC-&>=3:(5./8@"4.%D6)"-,5?($4.*-%5@+@='19)6@)5B6/#E1.?8('4<E%HHD;978"9/>.<-9DH3(4%:%>'26843)69%<$A-F%9A3*>.%+7C='(!@:!?*%-<0&#1,-9/F?FG115>H-8+E)%0BC)$:!:-//=%-=E=(8#G'.H,"B2@786?0036;B>;,H+<57.?293
@r886
GCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCG
+
?,<80@E)-*F0?>C@(288+:F/CF?:2<7<E"=<C4B*,3/*-*69-B9
@r887
NGAATNACCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATANTTGGAAAACAAGGATG
+
"*$%!!#!+*$('*))'(*#($+'"!)"+"((')()($*%#*#'+!($)!!&%)(%!+"'*&&"#%'$"&
@r888
CCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGATGTAGTCCTGAACGAAAACCCCCCGCGA
+
0../98C2A#!>ED)"4/$=>+788%6#*(/=>HC80<;$'6()8%3"'?4C!E/D;F@>6=6#F*3)7$*9>,EG(HBCD3.<,;>->HB)?H33>"7@'@=/B3:H$08>4"!
@r889
AGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGG
+
A?')690?*<A=)%A68F!F,!+'">F:))G,C->"8A@"4*>1=77E2#G&
@r890
AGCCGGACTAGGCCTGCCATCCAGTTCCCGCGANGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACG
+
,1-'A;51H:?',>=&<06G>C,.$9(DE4#A!;9"0;030?!@1<E4#--0;=:,6+2",1H*<G<?7AG81%.)$'
@r891
CCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTC
+
E'GC?*G$#0-().%HA;33E(B<7,)F$"=,'1*$;H=&A=$-H#(4="F*H-A83AF#G2*)H6F="#)%2F;AA&5+:3BA"8.14$40C(%?+;4#$?/9B<
@r892
TTCGTCCCTNCNTGGAGNNCGATTTNGTAANTTCNGTTAATTACGAGGGCATTGCAGTNATTGAGTTGCAGTTTTACTACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAANAGTTTGAA
+
**'(&%'*&!!#"($)*"!)''"#*(*"%##)*$!'&(&+*%!+"*%(*)#&++#"!&&)*'#$"&++()$$+$'+!%)+"&#&%(+$"%#)!**')'!%*")"&'*#('))"%#'"!("!&)'(+&'*+)"*#*
@r893
CCAGTTTGTTCATCAGGTTCGTGTAGNATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCNTAATAGCGCATCTCTTTCCCTCCATCCGCGATGAACC
+
8.(!),)0'0):!+@(,!",+;':44A,4GHH(:4+)'37311"9'65,)8:?5;;$41=4:=8=.+GC?841)E0#H>!5#/*6@.>!HD%#;@9,<+:BB-36D)>D3/*(*<&.(67$/BB$"
@r894
GACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACATGAAGGAGTTAGCTGATGCTAAA
+
%+%#(&!%"+)+'*%)!$'&(+%#+"%!&%&''*"!()%$'#$%&+'$*($#+"!+'+%(&!)!$'%))+)#!"+)&$'("##'#!%&#*)(&*+!&(%&*$)")+(#($"+%&*&(
@r895
CGACGTTCCTGGGTGACAAGCGTATTGAANGCTCNGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTG
+
FC9A2A2'2D/:64!?6*G;?0B;'F9@0?!1%%GE$>59HA&B/&3$7'7,$5#E<CD$F97A,5A!@01<)=0/BF+,3>D:?5(<:'-)>
@r896
TCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAANTCGACCATGACGT
+
G>G@$<'$,A1!.E*0)':B>2!@#H)B+/G$(.9<@+$-<)5G-0&>C(>9F*#&<;%%#;HC
@r897
GGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTNAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTNCACCACCAGAGCGTCATNCAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCT
+
-F<2D77#2G5&CH;#D-:2,BB.A6C&0F/<9*GH074)$1&7>;@0$(;B$<=HGE6B$$1-!1AH0<4G73#)&)/*%<7)(3B56$@);@D5B*D78(B%A#BGE<&D25H/9.3:4#74-9&3085(!)E<3';6&0D$<HH9E410=#,-A58*GF$:1AG@'(/E6(E'3%45%)A285:FH5=3"?;!>E),*3)%+#HBC:>+>G8:<?:=<;*5CE2"H?C?;;5$E%24%01#<)&D-9921:&?@5:1(%4H/+@H'6AH%9D0/+<!25#E7E$4
@r898
NNNACAANNNNTCGNCTCNNCAGATNGANTNNNTCCCCNCNCGNGNNCTNAANANNANNNGGNNCAGCNNNNCTGAGNGNNGCGTGACANNTACANNN
+
"#!"!"!#!#"!"!#"!!!!#"$##!#"$$#$"$##"#!""!!$$!"!"###"""!$!#"$$$#!"$#$#!"$"!$#!#"$$$#"$#$##$#$$#$#"
@r899
NCAACCNGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAGCCGACANGAGCTTTCGTGCGGGGTCTGCGGATAAAACAA
+
'-@,CG'.0HH!(B15GE$=;"60&=A%D3??1H@??H=H?16;=0DH&+&FF=#@C?AA2BD(0*@1:#H,CFC6;%89-A$#F%E%-!,1>FG*(1:98/A*#670-=.81C8B7?%%:B-<-"."/-
@r900
AGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGC
+
H<C,5!(84E35+3=1*7)3.;$+,F;>$F,!?B;>F202-8$
@r901
CCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATNACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGGCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATNAACGCTGCCCATTTTTACGACGCCTGCGGCGCGAAAGGACA
+
6+$G*CH!@(86)6@99-A$;7FB+).-A+5CEE29>$$>)*/<+0<?#:429B.3G-,2A1#7;=H;>DB:=?BD73@$)1">G@"7&>.&B>5(<E-FA@+9<556,4:7C'*/??=H48,!:5&)62/B*.1,-E7=G/>2&,G<(2+;E*:9'<'@.@%#%F+,HA6;+BDE@EH'C**&1G8/H&5D#C4E@!,?4!4:9;F/&CH=B.07,>==6;3A:"<+D#2&9-;%F7D>F
@r902
GGCAAAGGCTATTCTTATTTCATCTTACATTGAAGAAAATGA
+
6#!)//6)-9:)!&E*4H5G;*5(>0DG:3*=H(7EA4'>=;
@r903
TCATTCGCCCTCCTGANAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCNGTTAACAAGG
+
04&E3=7>3?HG"&?;@?F9/)5$6$@.32#32,:"*!G+BB=)%C14?7':C6.0;'"404"G2B/E!2$0()!=FB&FA"2
@r904
GGNTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCNNGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCNGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGNCTGAGAGGGGTGTCCTGACCGGCAGTTT
+
+!&&$#*#!*+"$&'''"&+""!+(*%!*')%'"#))''"#""*%##*$+&#%+(#"""&+*#!!"%'++'#%&")%$$(*&"(%+!%#"%"$&)$(%%$#$*(#"""*(*'*)*%'(()$!(#"(!"'"*#('&%&!#)(##&%"$)$$)))(#$+%&*('()%#!"*"'"
@r905
CCGGTGAAAGGTGCCGGGACCACCCTGNGGGTTTATANGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTAACCGCTGAGTCCTA
+
);4A$FA,"2E2B<1<93#*7G%&11G4!4+$<HB)>F#E,'*)?'.=;/@&@=-;/>4D>C/*50-%4-6+@/,$)+G$4C9/':@'6;=):5:%EF<5:&)@4)GD=.6'$!":B1=(9C":=C8/@#FH0%-1*>25
@r906
TAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACNCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATG
+
+E0"A*+!H.'D"@?#A!H!$?G>F0#E22F-E0#(,2'#D:6*F+@*2:1"%@7,&2=%87+3>76<($%66@9:.&>-$$(0%;.?@+(E0=E<'#D&+(9;=0A'.#:1@>@FD7+2%)HE)/&F3/.852<!1D4A,/*6HE44A9=9)14*'4D-7*D1<CH>9?*&A7F!&GC$
@r907
ATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATA
+
-**.*3B?F.;A2-1E+HD?!:D</$*6G$;/;6!'E!B=H#<6E!=-"*@7&$5=H=,7)B."C-)+(
@r908
GACCCTGCGCCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTT
+
+"*+$(!###%"&"")((!""$!'(&"#"+*+%"+%&$*!+"#*&)!!##"!%
@r909
TGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGG
+
H62=(?D(&6,?2<0,0%'$*F57H(.B?"F;!;E<ED>7%:C+E(42$3E.F#&HH&E:'.'B>@-<?/A@##/0?3<6.@A69E4<<">>9;'6#<%F!&('H*;C0>
@r910
TATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCNTAAAACAAA
+
.G,%&".D)2>38EGC6,>?+02D6G?<.;,/>/%2AE5<:$74)C5(B!"-+?H"'!'4+9=%C>.=B"BD564@D*03=#DD<9&6,A?#*(4$2*2%+)++CG!/:3<3&D-5%;#EC=$$./%<&
@r911
TCATGCNGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTC
+
>EAG."=>!D:1!!76A67+47?'=DD:>?05)/!,;$C9?G.,+/90$?$+/E.3@3'E
@r912
GCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGTTGAGCGATATCCCGGCACT
+
+!+$#$"*#)#'(!%)&#)&%"+%!*"$&#'(")"'!+"##"%&!%$$"*)%(%+&$#'%%)"&"%+#!*#+#"*')"!'"
@r913
GGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAA
+
2$?,9G5EA::6@!>4+22?5.;,)5.<!&+'05@&'('@F*<<:=G0H<;>+.)
@r914
CGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTGTCTTCAGGCCNCTGACTAGCGATAACTTTCCACACAACGGAA
+
D*24#,'FD#56B.%6*"*'.#-()'%8<&+.H6%6*"(8@;3196;H$$/<0,:.!@;@,#!6$*#C0/(6@%&>>-G2>9.?24?%?%A2A?9H?2?/AHA/$!0'CCE9%
@r915
GGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATTCCATACGATTGGCGGCAACCAGA
+
/3G5!'7H.&<$!3(&(!.E&D:3-(;+B%:-;D*<<'&&$6%:GD#?%B'/?77+05)7/0-.-&@;.?:G&EH@!(%<B+9@G-+$3/,'";.-D#=)E/%H233-8.B#4FFD+@9+0)>!1!'81/:&<2-#=E0.B*:*"D;#$&D#A*=-43;%
@r916
GCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGTTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTNTGTTTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGAT
+
31$/*8C/,F+!1@4=@4+3&+(2?!D9<E'%8%678F=5"57<3GH.H14D5.$$.<2EC805H2837>G"*9/6/%*.293C$1)A&H6.6/1D*G8B(H-=F*6D<%CG"+#;6)<*$!%7)(/9G#>D)6>:$:B<26&B1#==GE;F$AC-D,"F#BA#<D>.+48H2:/5*6D0BE>7H2*.E<*E6E$7/0"9!H$#@#E2/,G'!!$"0+1(+;FGAE574'59+:%/CA=
@r917
CATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGG
+
CH9C":089-F?*@/5,!8B/$/"/HGB97#,@$#B!*?DE=>H4%;FC5**B)5,;*.*&2"F4/E3&G-D@01%@?.(C9:%GEFD-20G.<8/#HD<2C4%$B0826!35-3E(;<D9,5E;")*!<+CE$H71=3#&56H9H0$0/546)%&)3H*#!&+",;H/3B7D+8H/D"7'6/!1$&'E)3<-#92@G
@r918
TGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAG
+
3$#D@(D0"><F3&)"B;$4H037)+8=99:GAGCGHGF10D<#=E@&(,*>/-:7B!0H
@r919
GCTCTGCTGCTGCGCATTTTNGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAA
+
*+$#*'+"&$%'%(!)&&)''($$$&)#+!*%!""$+)*$*!#$#*(%*))$)!$**$&'+#)&+
@r920
AGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATNAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCNCCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGNCCAGACGCCGGGAGGCNGCACTGGCAAGCAACTGACCTGCACTGCAG
+
+,C*@":>A*&3#>.'@+1+654'*?+/3;95$/#7D).620)C</*)89*0<7?-=%B@"!.E<A?.?"3;'0?%=$)0B#@D?E.+/E:.<!@7'7-?+H#@$:7@4.AE&$B5!9'-D4+0<,9#:G/+*%!@>B(7)-&C>F;<4,'*1#B!>(G5'H6/E(;G67!+H$>GB5;
@r921
GGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATG
+
:F8BB-5D(?@DCE!!@4$B<0+A,:-3;-$670D(<G.=H%B#/C:=CB@;<-(;:>)H-/@>.C%0@0?9A566+$*A;==$D;4*.87:>
@r922
ATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTNGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGT
+
H*44(F);)D&9%+%FF(44:)40$8,;/0=%@;#-93/!*#,G)&D%/154A$C:9BE)@G$;%1C1#E%*':<G4!E:603A@0>H=:E@H7F>4@=@/350-3%8&;+37E->/+8*5,4DBG%%"HH31#7<+-0'(#,B,&4HH8;5%FD*B$6G)'+-1GBG
@r923
GTCATTGAATTCNGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAGCGCCGTTCCCGGCAGCACAAATGCCACAGTTACC
+
*)%*")$&%$)*!++!&&+*#)+*%)+*#))()!$("!&+$!))'!)(+"()#(#("+%*!*("&!%%!#+)#*'(!!&+(%)!!%*"&%#'"+!&$(
@r924
GTATCATGTAGCCGCTTATGCTGGGAAGAAGCAATAACCCGCAGAAAAACNAA
+
0$3339@F"A2#7H#/DD6,H1F(4:D$%9B"':*3+=A%A*"B%"B&57D/,
@r925
ATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAA
+
7>G+B6D?78&(!EB(1H4G<=))GA='.85$:&@0H?/0%2;,
@r926
NGNANAGACGGNAGNNTGNNNNANAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTANATGGATTAAATTATGAAGAATGG
+
!)!&#)('"('%"#"#"'#!%$!!*+!(#+#&*++''+*#!+)"+')++(%#)*%"$'&(&"*)"$(*%#+$"+"!!#+#'&)*+'+"'*$!&*(*+'"&$($&'&*#!$++"%"$+$($'$)&""&)*%$#!(&()%&'$#
@r927
GCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGACAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCC
+
';,5)G9*8<#$B<*3/A4><4-><5*#!9@A6E/,95+&A!/=@@3::48F1/$H?+!.&(%H%#9='H8,5"C>32D@,23"#B&<?'('80DD#:/4H,0):!>>F!93(C7#$
@r928
NTNGGNNTGATATATCCNGGNGTAANTTNAANGGTGATGNCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCG
+
$!)*'#"$&%!&'')'(%)&$)()(!%'!*$"&&()$"%+"&+(!*'(!*#'"!$(*!"(%(**"'("&$#!*')!$)"))#+%(!%"#"!
@r929
CGACACCGCTTTGCCCAGGTCTTTCANCGCTGTCTCCAGCTCGGAATTAGTGCCACGACGGGNATCCAGCTTCTCCTTCA
+
"+*)!'&++&'#+)((&(*('(&+!#$(#+&&""*+%*+**")'$+(+'"%&%+!'%)***)&&&#$#&!#!+&(#"#%+
@r930
CGTTTCANGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACGGACAGGGGCAGCCCGTCGAGAATACTGGCAATTTCACATGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTNAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTNGATGGCGTTCGTACTCANTAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCATTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCT
+
&%@-"7.3%4)+$*:G4D;FG8+G;!=D0-#E==E8@0-H9.G"$)6"(?C.(<-<#?A'G/%,/(EA,G6/$1$C9C48"7$'HBCD/<*7$222@F<;"D;>H6H4"A/09,!GB@!-HG)-(75)$D5,=D(A!3&G.41!;H2"**':CH+>DH@53)+17G5%""D$*F#8%$7%(,8.8(EC?.!118->*<-"50,9C*+%-'G24'<?&(9-!H:/3+E>8(A-;6*97&=CC@'3("-7H0-30?"-<-(@F!+27H6A";8(2F.-=D?:C%*;$;
@r931
GNNCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCA
+
&#&+)$#$"#+%$**&(+("")())"%('!%$%!%$#&$"!'#$*&%")))(!*!'*'*+!"!&$"#$*'%(*)+#'!"%)%!%)&))&$
@r932
CTGNNTCGNCTGNNGNCATCCGNCNAATTTTCGCCGCCCCATAAAG
+
%('&!(#*!'*("")"!&&&%)#+"$%*#'$*$+*&'*#+!'!''&
@r933
CGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCT
+
1/18<5%5?0;$5<@$,,@1"$:1,.F6>*&G2@=BH"@*?@?'>##)+E*+0-3?BE901G-HD(:
@r934
AACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGC
+
-=13B-6CG3>@;G04B1%BC"+2?=-05-C72!1&;*-/7%0-@#FD9%D>0$+#1?&/3F"HB)H&=F1)!8+B;B?E!&)+%?-,E;$$
@r935
GTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAAGCAGCGTTGGTGAAGCACNATAATAATATGAA
+
&)%+&")&)##*)"%+$#'*%""'*#'"%*%*%*&!&!+$(!)'*)+&"&##*(+&##$!(+!!*&+"$"'&%('$+)%**$"&+#
@r936
ACATCCAGCGCGGCTGCTTTGTTCATGGCTTTTATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTT
+
)+;;@'#=B<BB.>F*+!01&%"'@3$:!C<@+=(+B,'5E)$(H><6C-.G!4=,B1%#>1)%&C=HC>
@r937
AGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGA
+
/)>;F99%";F+?>D<:@&B'HEG5!C5&3*GE19$;=;-+##H8>8;(96-=&"2(5/C!*C0C:-/@;
@r938
ACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTT
+
2,.:,(*7(E06GH+'4892=H8G5H3+-=297>?!$53,7@)'16
@r939
CGCTGCNGCGTGTTTGTGCATCCATNTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTG
+
&*('+*+*#+')!!*+*)((+"*+&(!"+$+"!"')$!!)&+'))(!!+#(#%+!'*"&'!&!(!)!&!)$#"#+#
@r940
CCTGGTACTTTGCCAACTATGANCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTGTTTGGCGAGCAATGGCGATGACGCNTCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTNTACTCCGTTACAAAGCGAGGCT
+
&+'%!)%!$$!#!&'!%+("*''+")$#*+)#((&$!)$+&!%)(((%($!)!()$+**'!!+)'%$$%)!+&(%!#%!$(#!&'+#%##%'+$)++*+(%&)%!#*'(#+&%$"**!+(+*%((&$*'$"'&*$%%+!*"*&!!%#)"%%#+()%!(%!**)')(#'!"%#"'%&%*&$%%("*#*%#*+(!'#(*(&$#+&+'!%%*'&!%&()($)'%)+***+)(&$()!$+(+")(#
@r941
TCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACNATTGAGTCATAGAACTTCCATTATTCTCCGGAAGANAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACG
+
'6F(?690HD2=D<7:*C=7.B+:#9*1G4#F*:@(;?H%5-1E:(DCA";>"GEH-B'2>D7C>=('A#$@*8,5;$.@+$)@%B<2*DDB4G%6$4+?@.H?A7H&%C<%6'-,H::G"B-@&E';,<>0BC>)96>%F3@,,0F,+2*>HC07F7&C'=>09H7<@,$05;?&%@D4C!*
@r942
CTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGT
+
35DA?;&*+'?-)%=D)D#9A@!"25GH#A%7E-5<32D)10+G,?,,DFAE2#-*.('>)7&"7!017A!=5AE7-""$!0.)@4E#9&':2(F(>-B(H/6@H273C55%",>&.)E@//.-"9-%
@r943
AGTTGACTGAATTTTTTATCTATTAATGTATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCT
+
32(?.D:0;!)4GE0BC<,>4A(4A!C%816.(40H<?+G%B%C'CB<)%'*;?+6FE9B25<6='@F/-:-?8%;>2/*5!75C/6/C*87H'#*B91;D#.
@r944
NCGGANCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGA
+
#0$!'<F$F!>D060!<-:*@"13/6?9$*?/C!#),41-4."+*'GB<-<3D!5+D/8A$>0!?1<*6%*/E"-#(@4=<G"D,#'53=3/A74,!AC"=.E)$/('E<<'%C20B
@r945
GCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACNGTTGATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGTGGTCAGCGTTCCGTCCGGTGTCAGCGAAAAGGACGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTT
+
&$,.-AH:$-8,?9D';H?)9.;5F'$#A!&H10.#5.1/$/E;>B1"2@,@31DG*=.6!)(?,27=F880CE8?A7(E<38>03@F#C).4"G3-4/+75%1?+)((&&H8!7:E0%)3:*0$%H%D>%B5@;%48*CE*?F+"D+H".C5;+@GA$E5D#.E127#;/3$6-F5&5,!*5@$A>6!CH*!E5<!D6$?):3$GH%G5F/#&.A,?<A)B-);'.=G!#:#)7EB?G>F-;73A*2C!'>C:B!(9>0D3#,:+F#*-8:F2;&./9-%D;1
@r946
NTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTNAGGT
+
%/>A07$&3,"B+43+#'@8#(F3+>@/-D(<;@6#);4F@!H
@r947
NTTGCNCGNGTCNNNCAGNGTNGTCCNCGGCTCGGAANTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGCTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGNTCCACTCCGTGCCGCTGGACTGCGTGATGTTATTCTCTTCACTG
+
%#')*"'$%*$'"!$%)""&!!(%)&&$!)"$*)#)%$++*'#$+"$%'&&")$#"$)$("#($)(&&#$*%*)()''(""(*!($(%)+##*#*'++%$("$'*(*$'&$#*''%'))+%')$$*&'(+!%#'"+&""'+*%*$)&!"++(*"*"$($$%(*"'(%*!++"'"&%!##(%(!$'$)!"+'++#+%)$*'&%!)**'*)$&%"*!)&**&*$++*'*""(')!!)$)(%%&*+#
@r948
ATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTA
+
++E@.!'15F81G$#021<><=6*.<GB03E5&("$>*>)DE7FDBH$C==9*6G'%.&%CF2$*%
@r949
ACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGNTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTNGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACG
+
).6?*1',731?3C+=;CAE>B-5F0<+A!*9@HH=3>!0D<C>@HC6048B0+4=*$61E8;@!608-'9?;.02>8#&2FD>F48'+$9!5.4!0=D)=E%.2%94C!&=@B;':67!=+-'A=A.#7C4G)07D$2@53=!H.7.>$H@BA-53%:06+:<FDC,/-8C-6%9<6B*#?AC2(&)G.B6?>(3E.!:6&$>$5"+&4EF8A''D%,.*5%>0;%?(.G;B$/#E0$!B$H??)769/@&,5
@r950
AGGAGTCCGGTATGNCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTC
+
F""2%B$4?;B!&"%F'?4:)-;HD>)E-)"'-95-DG4)%'3+/.)HG('.A./0B<6)"0#&%,,#>DD;-;(AD;-*8D#3EFE0A&&".H41
@r951
ATCACCGCACCTGACTGCTCACCGGATGTANTGGTGGCTGACGTTCCCATGTACNCGCGTATCGTTTCA
+
1+@&+GB/@(=)*'2,@"+E7)32@%#70/E<80'CB$&?.<-77H=4FCD!#D&;&$!*)4:=?+&F!
@r952
TNTGNCGGNGCTTTTTGCCATACCACGGGGCCAGCGCCNGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGNCGGCAACCAAATACGGGTGTTGCGCTGCTTATGCTCTATA
+
("*#")*'$+$%*(&%+''*!#(+)#*%#(!*("#(%!*)$%%$%))(#!)'&&"#)('!++)'"))$**)$"!!)$#*"(%!*&*!"&&%+%"'&$""%$$"%+%)**&$!&#%)*$'!&"+%#+(#++)))#&$&&#(*')!+&'"%
@r953
CTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATATATTNCTAAATCGCC
+
AA*)GG/6*).&&0.%@49DHC'&(01"D"/'E#+$??B!!++=5C8=F7!-#;,=$B097'H+0+A@912!
@r954
GACGCGGCAATACAGCGGTATCTNGGACGNAACGTTTAAACCGGCATNCAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGG
+
671D*?>;),C$21@8<.+-;A:%6+BH)H&B5!'::73,H9<!!&+)%!&F3>FBH98?"":9#/ED'+'/!=F"110%0G83&?H##D+><(2'*%<EDE*3-05GF64'/%+)>=H=G9<)=6);>?!,,C&3<?"1$>
@r955
TTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCC
+
&H9?(15D,3FD-0@:'8>;($*!'45-;,85.DG)&,G"#E(B0@5
@r956
ATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATG
+
=<H!'80($@'.@&3-08(2*0?3(DCF';<EGH&#;',C89!5D&?8'@F$78)@$!9-1@E=D2'H;A6<C(F.C>E>%?8=="-(.);06'$,)&E*DC1!='?EF<58)=#H9#>??:*!,%0/A/9HF3&7>;A!2C"1C%02%"):C2;"6F,H0#634:9E2-6;;(&(FE1'46G&</<@</:E4=FE2%*4F!@!A
@r957
GGANTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTNTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAAT
+
"&*+$%%&)*%"%+%#+'*&+'*!&"!$'$*&*#%()(&'&+#)+*(&%+'&)+'*"(!!%(#)(+&'!!##%%$&*+*+!$$'"&**$("($+#"$"$$!""&&'#*)#!+(%)#&$!&*#+%+'
@r958
CGGCGTGCGATGGTGGAAAACCGTCAACCTGNAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGGAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGT
+
8)@@'&#+.'+9H"'+9,:G!9H6;:$G"'2H9A76*H"B?3+CB5=#3*'.?+7=%82()$@?46FG44>9>>,@9836:!29<.E,85(6,F%C&7#A:0.#F)628>9+"24G)+B%.<H8#:E8$7E*3/,=#
@r959
TTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGT
+
;"E&.6AH/()2*FB@9"#2%#.#7B;&(;!BD<CEC+=<?&;.
@r960
TAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATNACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCGGNCTCCAAACGATACCTGTTAGCAATATTTNAT
+
0CC6@?8??0GD%&E1:":%F8$H6(%2%G5+/7"/F(25#G4.88(HG,ACDA'!*0?:;-91-D84398'E6C#F.)/""+9;@+?A@098>DF8,AC/7DGG6AG:E"A1<>)A3F-;;/.F11+0HHD6AFF>
@r961
GCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTGT
+
44$$%.+6B9'"5#@F$&(1&A(;$%!7GB4@C'(%1:/#!GE,8#3&B*?
@r962
TGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGCATTT
+
D&,A/077@07@H4?<F!3+0,D6'@%@%7+3$9E$1G*9;%D?6
@r963
CTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGT
+
75-B-%55")FA-B'B(*#(:),%B0(*-,!01C76>@.<'+%#?/1?,B@4
@r964
GGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCANGACGATGAACAGACGCTGCTGCGTGTGGATGNGGCCATCAATAAAACCTATACCCG
+
-7=+3)FDD%%"%#>7992&42,0&C7,;7(1G7C40*1(1!E?5B)!#?$0G9?#>#='C7?+?0%9#+H=955$*$A-E+*4?4&C+#'BA::0?>:D27>>%A?:6"".C*$154167B"38#)C*<1CG9E!="!#3-2D(-%'9BFE<&0":F
@r965
CGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTT
+
2?E"4'-H<@4(%,!$+<)G;?7&*"!5)=DGCHGCF#%"G5
@r966
GCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAG
+
>8##>8:*E+6&:(-D%;9/EC''5*@%D:'6=+):06F=4H%-1H9.@1E&?!79*3#6CB>/#115*H3?8H/A/-);:E9%6327E3@%@+$#D8"6*+6$)3!"8-F&C!2&($39G4?$FH
@r967
GTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGT
+
>9E;51DG.3039*(3:E0B71C79D&:6!,-6#81B6@F"(*C/;+:=94):?<66!*!=C&=7B)3;G+>=3B!G*=8(2?A$+
@r968
TTTATATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGA
+
:*/H34D'!H4?/:0/C#F".7CB1636D()+0#D":3AA+D>3>
@r969
TTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAANGCATCNATCTT
+
*D;5GA6-+C47-$!?>CCF"0G9$H?AF7*"?,<*#5@*1"<A.%)0,996'#<B=+9GB4H8B
@r970
GCTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGCCATCCTGCGCATCCGGATATTAAACGGGCGCGGNGGCAGGTTANCCATCACCACCNAGGCCAGATANTGCGAGGTGGTTTTGNCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGANTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCT
+
@&9+A<*?F-$(9+>)=,*4,9;;01(<FA!/@*HCA).;?5+?CA-@4"B+?%!<&.G>4,#%,0$0F(B#A(<%?H2H$C7../-%"A4"2<=E*C/"C80#8'!?609)()-A!<G#7<,/C"?/'-+<1%H!.C@3B?(BA<,C&81,9>.D:+'B;/1C6$CH=&"(;,0;-FFHFH$/8.9;7:0<)>",;#"?8E-(4#AGB6#'?71+4,6&,(8''G6F<F*03-!%9D?.).B;":*''0<+3%A3G<,44G:#D>),6'&%2#C6(.1:;%/>,/H265C)@HDF50<H7.!5./(G$*CG7!9B2C#3!5)7C=EH-
@r971
CATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTG
+
4!9BD;!4>5@##>./H"#!0<H.!6@/!G1)*/H:'7.-
@r972
TGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCC
+
6AF;,%.,:,+/'2!8C/;C=*E:<@">?&4*"45+3-2&7%
@r973
NCACGACNCGACANTCAGCATTTTCACAAGCGNTANCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACCCACCTGCATCCTGAACCCATTGACCTCCA
+
$"#)()(('&()%$$+')"&*(#)'++%$%(+!"&&"(#"'+(&))%*!%*)#('!#*#'$#*'#"$!"'"'!'(")*(+*%)*((+!+((!"+$)$"%)""*''!$$"&(+++)&!+"%))$*')$)%'$)
@r974
CGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGNT
+
9#>:C$@:B0F'!'6&,H"<D+(7,,?".)3F@+&-!>4AA>$E;.
@r975
NTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAA
+
*44@5,"!A-)+)$*2:%%29<D(!',B1-)+60'97>C8,AH<'+B9,DG*&(,"2$3G)1F?6,+4B7$)-3',HB/.7"(%2H5;F9BGF&:HH/G6*(0'CC;(B(2"E@$*.7?&8@ECC%>$@18;?>0G9E1.
@r976
AATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACNAATATCCATGAACAT
+
4<+;EH?./7<4+#AF/'9.E2//'3/%4(1DF(*-/.0>>=6A'$7'*5<)+8(3B?H+,$$5/G:1*!;0#GG+!.9*E<HF+<8>A%#DH*?%<'0?H08('A9-AB..??C.00,93>1.(98FH<<.@%/.4;,49E=G?.G('!1!H5:E91G;&:,#%-2@,BG"(87+C?:!?7"+(:H@B+(/D%+4;+(+&.-!%*(83F)F0=)?<)EFGF4+C5A2-'9(<E81!=28/H1#DD6"73%C:=(H@,>63.H2<$%.3D3>(7H?%*83<!>$@2+9#,A"36%B12H-C9@,,B'5.F?65E=<G'G2#)H,2<>5'<1A#F'4?(.8=#E8.4,7(2B+(H.0%<@H0'0<DA35
@r977
CGGCAGGNTGNTCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCT
+
%G=$<54$=A#D/2E/FG4'E1&?D6D)=!%-##F()1(C1)69'?H01C33*>F7,A$8?)!.%/@+G;@-'/1.&
@r978
ACCGATACCGACGCCNGATCGCCCTGCTGCCCCCACGCATTTACCGC
+
*!B..,6:4!'HB00-'23.'@5,%8C-'.@=8'C$+&<>$E,9?;9
@r979
TTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGG
+
&A+!<"<GB<"7.H@$E,:7>6?<;B@C40#*/%4<'/@@01)507969)*)%,;/>
@r980
ACTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGATACCATCCATTGGAGGCCATCCTTCCTGACCATTTCNATCATTCCAGTCG
+
%-C-.23<!#0+B"0>HE)069@8%!$>%-;B.1'.2@D$"*4,*'H=BH=#+,.%>BE42"?E69331H;#9-;5::&$166G,E86F5/+"'"4<"/:>)C=0/G7!(/+0>-./B@07#.!=&%7:E7E7D7*B-<=A?D)+,.5-62G.GC$H1E<D%#-&CB%6+!G&$712'647':-(+H+3!(A&1
@r981
CAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGC
+
>3-$A&/7*G"1<A34D=777@H:69!,-,.;*FA'128H"*3%723-*
@r982
TCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTG
+
)C#+0<0&H#:<C2%C(%.H<5F?3.<44G5B,@D!#&&&'5FHE=6629EA&/H,;9<4!!*$-:#)C:#<@?6C5H!8!@&03/"F0&4/B'B6?14A!AHBD)$3;+".FEEG3,,52,#F.31-*<)'E2)#2H
@r983
GGGCATAAGTCGGACACCATGGCATCACAGTACCGTGATGACAGAGGCAGGGAGTGGGACAAAACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGC
+
4F0D2@F3'3$%G'<6H")1%:=;0H>6/+1+=39;A$/F01.54//607#;D7'?<=+>29$;H?'",%>+%#A:)3"1&29:1E.2<39(++D1-C8%1C3#,(G+&H4FC4?0<3%%ABG(4%33A
@r984
TCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCA
+
4D,'0C-)=2>DF&.)-.0:B&C"%/5<"G82%$E9<<"*<25(010#G3E&+H32G5!,37A+,&G=/1&H8;;!H6+A-;8!A9."=,/7?!&-)B9:C@=!*F@(F+9%%519?6*+:B9D/
@r985
CCTACACGTAGNCNGTCACTGTCAGGANAGTGGTAAAACTGCAACTCAATTACTGCAATGCNCNCGTAATTAAGTGAATNTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGNATGTTCGCTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTTTCCGACGGCAGGCTTCAGTGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAA
+
)&%*&*&($#!&*#+'+%())"&'"$')%**%&"#&'#&$)+!%'!&*('$("+*#"$#"*%&)!$**%!"(!$#+%!)$''#&%"!+(')"$%*(&&#%$(&$%"%'*!$!*(+**$+"'#!$*%#+!*&*$!#$"+%!*#**%*#%&'!('+)$#($*%(&)*#)+&%*%!($&+'*(!((('((!(#*'%+'%'''%'+*%"&#(#+*(#%#*'%*"+#*!)&$*)&+*!%&*"'&%%%!&))&&%#+$##"%&$+#$'#)#
@r986
NCTTATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAA
+
"")!E),,<6+3?$(#7D'0D5-2/D(A4A*HC%F;;,@2/:H8)(998<807%-F92>D@=0)
@r987
GCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCTTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTT
+
#4=00+#GGCA**3)G*4$.#:8"9DF54;?.884/$B!/=E;5*F$+A3?;E2$HA=,*3892)9!3)/1;$B*/50F=8.!,H7,@,,%4E2#<6#<DE#1=$57+8,HD.:AF1B)40G,C+)F65A>68<#E<#7@#?999?H,A6'4AFC$?1@2.:/69(>0!E*3AHC@C/+G4*,D>EF=11=E7%H9(
@r988
ATGGGCCTGCTTAGGTGACGTCTCTCGTCAGNTTGAATGGCATGGCCGCTGNCNGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGG
+
8<()F-A&(6<8%5A1%CF;#,:">AA.(=E;3H%B=/;4&0)96H8(A<"(9$0<!&+-78D#8@G5*<3;;30<=B$-%=0*B?G0/5$(E9)#!-E,/!@9.?31$(3?,58(;#5G)@688=D,$(8><*==:6>97%0(D%:9$=F<!$!-&/++C@<$@5)=%@#15)='"0191%/CB7880<"-$2D0,@-8+,G84+67:B0,DEB$<F1G%/(8*(#?38G@9>+
@r989
TCACACNGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCGTCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGC
+
G50.B7BAH%4D"HC5,$'/BH6H0F#?0!<)*#<#-=G)4-(78G;-H"B-#DF1%H8!GC/G/CD!&,#0@9'C3CE-";=E0@*:;*//3D2B30-!$H;&=&1./#=H)>D3?-/C8$@/77%:6:.2$0B4?1<!,,?<44>-E24<3CC7A&/
@r990
NNGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTNACCTGNNGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGNCCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGG
+
"("*'+$+'+!+)%+$$"+!'')&)"+'"&)"(+$''+($%&"%!)$$*+*(+%(%")%*""$$(+)$%%'!)*"$%+*!%"''""+%($+#!%#*'*!$#&+))(('"+&*%(&"!$*++$$%+*$$)"*%&'"#(!"*)'($&%$!'&'''#(($)*$$+&#(!!"!$*"+(
@r991
TGCGGCGGGCCGTTTTCACGGTNATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTT
+
'C/'#7H@:*@:%,!9,1,$4&B(H5#+=H9!2F,!,5,2(CD/!:3@E;*(@'*C4D1HE-EEB.40/"&=A8F"8)GE-/."G5,,+E%:%?E'@2-!AC/E>%1&,7.-B7+&*8?,&C0&>18%'/!"4,8//)50"H
@r992
AACACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGNTGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCAGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCT
+
$#@0HE37?:.)HB6!,A(A7)G;D=0,C#(%/10D?H'H%%H/73!*9?>@1@"<-'?C6"'&15%9"C77$"7=4E1$&3B4$?-DHBB2-56;&?>4*@@&E(1')#;5>&?D;'5>8@=:*4-$*GHAAD?'14(&>)14>9C;>B-88<DC"#>%%9%0?>FE#@B"G#2,/:>@;=G-039F%34*3>86(@7$GG%A);.)%'G)31:4'"2A-&*6()&A1"B6*
@r993
ANCAGNNNGTNATTNCGNNGNCNNNGCATGCNNNANNCGNNNNANACNNNNNGCANANNATGTNNNTNNTNNNNNTNGNCCNNNNNNNACANCNCNNCANATCANNTNNNNCNNANNGNCNNNNGNCNNNNTNNTNNNGANAGGGNGNTN
+
$#$$$!"!""!$#!#$!!""$"!""$$#"!#!#""#!!!!"#!!"$$"!"$!""$###"$#"#!!!##!$"#"$!"###!#$!"$!""$$#""$$"##$$$#"###!#!"!$!$"!""#"#!$"#$""$$!$!$$$#"#"#$$"$"#!!$
@r994
CACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGACAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGC
+
04=,??2&48A'B<04;G0H'BA5,"A(=D/+=6H6FB<(AD1D1&&=2&C1-<020H:6"%2'564G@!8$=G#52:/+;E=5HA)!"*)D1)
@r995
ATGGCATTCCNCTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCNTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCGGGTAACCTTCCGCA
+
))"'&$(%'*!'")++'"!!)%++(&(%'*##")*!$"#)(""&(#%&&'"'+(!)''((&**$*!(')&+*!"#$'(*+*((&#$$')+!!'+%%"'("*%$&*#('*&($+'*)"$$"*+'$&!("'&)+##''))#!+($&+(((%&)+$$)*
@r996
GCCAGCACCTCGNTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGANAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACC
+
3G)6:B(;9)"7,%:20@;A8!,>@G=75D>:E874.5!G!AB38$!-/)>@8<E)@=7?H3>H,:04<=0=<05FG$<,&>2=B)79>F70:E7))CH<%5B?1?F69!H!5-'C>!-A%8==+7A)&64-,A?*E;.F%3F";7)759-56.@1$H-*G'@=H4)6+.%/-+>B"+#G?%!1+$=H3A4;8'F@@1B;**F$6GD2)3;)B?/E7-&C*A=;A%C)D5%0(>B'781".'%A:@=B*G/;H2$@#)8B289=F?,.D#6!C4%)3&$>!#3CH1=36*;F2(
@r997
TCNATCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATNCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATTATGGCCCGGNTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACNAGAACTCAAACTGTACCGTCGG
+
&)"("+!"#)*(*'!()+&"()"$+"%((%&'#")+'#!$&*#&%(""#&$**)"'&)&"%#%''%'!#$""*+"%'+%)&*!"(*$&!!'*)(**+!))!%%"(!"$++&+$$#)*%%%#)*$*"+*%'(!&%(#%+#+(')*"%#$*$&$+%!(#()&*''()%$')&)"#'%&''''""#%%&$+'(+"(%")!)!&"#*"+%%+*$''+$#&%'%!$)"$*)#+)!+)&!)'&&%%"*(+&"$"'$*#(%&*%+&+*&*'&))()!%%)#*$#$%%%
@r998
TGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTT
+
3?4?7+->+8'#!/0:-67=,+9FC(+?=9>(B>+/>)7D
@r999
GTTTNNATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCC
+
(!%##!#)+$*"(+$!"%&&(&(%++++!#*$*()&"''!)!*#'+!*%!+%+($
@r1000
NGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAG
+
!F,%%3A9)?D',?4=@',"GC:;C+84D+D>!.@H>5,*90C8$,7.G,".>'C
@r1001
TACGGCCTTAATCCGTGGACGAAAGAANTTTACGCCTTTCCTGATAAGCAGAATGGCATC
+
F@%A8*+6(:H;B+A6A1G'/H.8><FE:G*5,96486+EHE->AC9DH'F*EB83*:'D
@r1002
GATGCGCGGCTCCGTGCCGCCAAAGCNGGCCGNCACTGACTGGTCGCAGTANTGGCCGATGAAATACAGCGCCCATTTATCCACATCCGCCGCACCAAGAC
+
>)48@=*@8*4.F./)654H)%16!4<F9C=.G6;?@=232+$,A.#;"3*7B;"G>"E+#1>,0#-*92?B='956C!5"2&!GD$;!,4<HBGC$7E1?
@r1003
TGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTA
+
%=;$$8#.+78,'+/)?5&'%3(CE'94H-GA&DG03(G"-B3!%B?A5DD%H+'
@r1004
NATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACNATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACA
+
"<%C104(>FED;44?A?$C7&43(=<5B7=B:<F>A"/>>>=))-<40;0#>-;'/AD<$//GA7*'59%F">H>9@+2C@)/(BH'2)*A)E94$6='0.!85:)%;-?%%G8C
@r1005
NAANCNGANNTTNACCGCTTTCCCCCGCCCTAACCAGTGNGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACC
+
&'%()"**(&!%!(#+)"*"'$"#&(*!+(($+%($"*!!))$))(#$&($&*#($$#$+#'%(!("#$+!)!$'##*#&!)#%+%"#%#)#)'*%(+'+$'*"*'%+'!*%#"&+"))$)#$"'%##'&+)+(#*'(*$*)(""+*''&$#'&"**'*$"&&#'%$%&#"*"&(&%(!)')*()%&')!$&
@r1006
GCCGGGAGCGGTTGCGGTATGAGCCGGGTCACNGTTNCCCTGCGGCTGATA
+
:#!>)*G!C0:E+H?B=$4AD!G+/?6$595"@H8#7&;,*,254*;FG#2
@r1007
GTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAANGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAAT
+
H9=2C'$+GDAA206,B7C-##*6)$D;@@?(9:2H>7)%)F8A9GD/&4D3EB!C*;)32?0'D:$4D9!2A.407G&32+@C":%B*/788=076%->(?5D2F)@G<A0,H5(:')19#!#EF:?
@r1008
GTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATCATATTCACATCGTGTTAGAAAACGATA
+
$G888:D&@:.2':6:=>"@<885C;"H5$9$01B23.69+H31GF"%D7B#C!/!;%,61%44%$%&@$*D$68E,78.2@/EE:-
@r1009
TTAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGC
+
*"%+%$&$%$'$$')#!%"#&()"#('*'(*"(!'!+%&&'%()(%((*
@r1010
CAACNTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGNGCAGAAAATGTTGTTAAAACAGAAACCCAGCAA
+
"$4?61$!,6!)2/.<F;&E0->#/1;!!6;(@GH"DF*/)CG&45!/H71@E'1A:;%5"98$G);73@4@:/:.2%0C=+=6E=**4?%G;6BC'2+0<%=?;$E6H1&)*3.1*F!5,55=A9//E3GE)-D;=3:=/G5H1A=</)%:+-0:,)?@;;@+$)!4A'(>G7#:38*'$F7#&;G#8E;$DC0'0-D>20/=;:#A%948:<&G<#08=-8=97,C8#&E0<A3:0C:+'
@r1011
CTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTNTTANTGCTTCGGCCTGTGTCAGTTCTGACGA
+
E"*@CG7B$7;A4>'@H;C($+H7!5C15*G*#=+*,5?'(('8D-=+(4@$CH%--)17H2=,)#
@r1012
CGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGG
+
->7H1>D+@70;8%484:<2C#93#@&?)4)50>2;/35,FBD%+E3306;4
@r1013
AACCAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTT
+
)($+#!+$"(+)")*#*$)"&#&&&)"($(+(((&+#$+''$#!+'#**+$#&%)!!*%*'&&'))%
@r1014
GAAATGATGGGTGATGGTTTCCTTTGGTGCTANTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTNTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTG
+
-?C-5168,H49.@/DH2&DF@61?&+70&%7%D?2#.232B058AB:5'B.B)@'65C9'9F;.1'?9,?(2<"A@4$"A#(=E-.B&%%#=%@;1&3+D535$0/*7G(E)7/$43"<A,H32CFE5/$<."*/%?GA7G#&H;
@r1015
NCAGAGCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGNTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTNAATTTTTAAGAGCNTCACCTTCATGGT
+
!#(#!+''"!)*&##!#*&&)*&!(+(&!(&&$'&#(('%#'"%*$()()&)%*#$%&*+$#)'$"'!)(!$$)%%('"&*&#($$#!('"'!(*)++$$#&+%+$%&+"((')()%"+$&!*%*%+!!"))!*#)*$!"*'("!'*%*+$'#*%$!)!%
@r1016
CTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAG
+
;F"$?2',G<=:258%1#3%A-%?><8B(>/#.9'!7411H<-A76;&.
@r1017
GAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGAC
+
C''DA3"E33)B@0#$&%H2?*";7#CC<;;+E"*0#33,/+B".0F#%*4
@r1018
GTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATNAGACGATC
+
2;,/83+>:H%(B1,>1H*"B":@;;$-D>&FB)+(#+-2ED%&4
@r1019
NACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCNCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTT
+
+>98:55!&G:<;%@?*2>1A/.4'C"->1G6BFD%0,B.0G3!A((.;7'C0;'):&3&%,C"4<*2=>G&#=0?5)09)2<8%>&5*@).!C/437034G,$<.>0A#/B$DH(:?57;E5.51$6B
@r1020
TNGTNTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGNAGTTAGCGCACG
+
'"#)#(+(()(*$%!"+"##"&&)*'$**&()))"!'")"&#'+!)'*)($&+$(!(*$!###!&$"!"%''''%"&&"*#%$&##%('$%$()*"$()&*&%"!'&$""""*#)'(&$&+'""&**$!'*+++'#'*%*!)&!#%
@r1021
CNGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAA
+
F1)/F08-(D&/:')+%*-H4"!*;913,'(*'?35@HC2-$)B@H-
@r1022
CATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATA
+
73(<#='A<0(H?=>B;F("7=5A=B0=;3'C:/!$0@$$E7+*1;>0EE(B*>&>&4/;('-"E?7?6?.(G@F-&8(742EB0E=7E-F&2-+D#0&-FH570G=>
@r1023
NGCCAAGCTTGCAGAAACGACTTTTCTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGA
+
#H77:/"+6H2G8E/0/F(B=<6:B,A?@6DD'&2-31);65=-"-&+A%,*4790'0>&0E:H,<
@r1024
AGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCC
+
/5D#>F&E!F39FBD:*=FH=D&6.,..=E593*.AA?--FAB1&E@3/;#0
@r1025
CTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTNAGTGACGGCTGCATACTAACCGCTTCATANATCTCGTAGATTT
+
639F0,4#=C$34>9C9(>59AA4GAF0DG.):AEED46>:#?6"'F,'1959*"$!0?3!/>2F6###.A"$!,1?@0*/G!/B$0FG)&BF7-B0)4F%>%'&#<3"
@r1026
TTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCT
+
"BE"?G&3'FA4)?0?$7H%E6;#,+$35/=>!=785@+D6>7'"=4G=-.1BC@1?9.>
@r1027
GTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCTGTCGCAGGCGTCCGGGACGTTTGAGCAGAATCACCA
+
=@#*9(?21:+BF=.0"5"E6#E)4H>%;/-/*9/(=0&%@/F0)8@+#8%5"2''<%D30<6BD"H%36-*H&;";:-93?-4A>%H374,'#EB=;E?+-:$=(AD4(B26<;""3*EF99B5,@,<4*!3*"9G%7/+:/*1
@r1028
TTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGT
+
/4)G840**9%H"1,#.C#*.F-('0>35%)FGC9$:GH?:#0D<92#4A.4BE
@r1029
ATCTACGATATCAGACCNCTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGC
+
/)#3/3C+&)*08",*B2B1%C).H:4<,GAG+33+G048#>$</$/+:!90%#+5C64*2!7H-4&!C<C0B%".-/<B?+./3$H&!=+9))(078+@C<?8.A?!FD44+#9;$*/A.G#6<7?)(C02EC!$=6?>+<!>;28(-5+3B@EC-A+CDF2.8;4>0E+4<1(?4694$',+0HF/"A4
@r1030
TTNCNTGANTNCCCTCTCCCCCAAATAAAAAGGNCTGCGATTNCTAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCC
+
D#C5:+DH+$,0.?:2;:64<(@+?GEC$4:03D)*()'3*12F/""1@#!--+*=;&(F*0".)?*!H2D8/4G09/912$4C6)0G?,'$?>4#-4D%0+(7G5/*8'!
@r1031
AGCAACTGGAAATCATTCAACACCCGCACTATCTGAAGTTCACCAG
+
!/<7($$+,/?4'/7HG3<:0("6C2'97FH9&9GB;:54A>EHG?
@r1032
GGAACCGCGAACGAATCAGCAACTCACAAAACGGGATNGTGNAAGAAATCAAAGGCGCGGACACGTTCAGCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATA
+
BBAH%A7-<A/D).@)5?/5=?2@+:?GE5E"-97HA=8785<$B2C".7)B91#<@.<(FD7D@C;&&2')@.>8)!1:76D:B'(9AH5,7?-0A8?H,D4-&"0G4.1:%E(91-%':EC$F)$/<
@r1033
CCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGA
+
C68/BHD"2*.;+.)6?A<6D<9.A70B$"7+<=-,5BD0!'%8GD/.BE%>G6'"+G"12)B<**B=E53)($<H5#46-,,B0.#!=09:%?<D99H$?AF:3D)/.G#$''33074.%@$/@7)(''/;9"*G)<A3!@=3<!!/A*<=?%$H>97#27,+!/7+17F::0AF'A(?$+,,'A("<
@r1034
GCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTT
+
E6*4$??,A(9BF."%$%)+H9%/;G&FE02A!:(),<C3'&'5F;$#53,5#8$74;'/63D((-).8!><"(
@r1035
CAAATTAAACCACACCTATGGTGTATGCATTTGNAACCTGTCGGATCACCGGAAAGGACCCGTAAAGT
+
H<H'7H1;'D:.#5';8G1#8"'F31'5$8"#57<+F+=F!>@(')$:(7$16E56,CB:A01#3A=-
@r1036
GAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATNTATCCGGTGATGAGCGATATCCCGTCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTA
+
/D61?!G,1#.69*?#'D&BAH?5@D9A";CDF&4;E%EH,C%'5'@BB7"8;'4.E;B(&":,D5#92+A/9-<,#;0&5;$05#*;-7!(0A1F;0?@A+E%AA52B";#@;#?2C7F5A5E7+7D!9:#>&
@r1037
ACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCNTCCGGTTGCAAAATGG
+
&H;<$%)%.CA8+5&*?AH(/?F%=<F.6F"F"F@E)#%=4/-132263"487>F"6*8=4@%;,6"GAA>GF!
@r1038
GGAAAACATTTTGTCGCGGGTNTTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCNGTCTCTGGTTGCCGCCAATCGTACGGCATTT
+
:;2&6>=>;>;))C;?1FF8.&%C-2-&!C3#1@'1#"-92DH4!5.$G;/:;(7G-<3;.+85",F"9%48458$60!%&,HC%'#F'7,)@2!5
@r1039
CCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGA
+
F)&.%'*!EF4?+EE@.C+?=?,1&?@4>:E*,H,)<H1A&1=HB(50</B
@r1040
GCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATT
+
@=?'DGB2#:%$;F>#<5!$)FG/&"#5C)A'H#C*C3=:12G9.'&(&B%<'9>.:?"/&B'@78:!)&
@r1041
CAGGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGNTTCCCGAAC
+
19G8?5BH@6*>DE5*,'//F(8%0/6,#>D9%$8(EC2D=AG:$64G&B*<G:0B%)/16'7+08=;7H'3
@r1042
AGATGTGAAAGGTCACACTGTCAGGTGGCTNAATCTCTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGC
+
4503$4)2H@(-D;9B997>+)1FA'C95*FA&)H;(*5H,)/;6A='.A26$AH6#<@8'<>=,-4!62;1<5)*GB#61::%41:,E24!4E%)9G(6?4!;A2,@$
@r1043
GAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGG
+
A3,$03B2H/A(D0G/==5)F(8#'9C,,90>5@61>@<(2&%G&E6;@G
@r1044
AGTCCTGTCTCNCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCA
+
%'!$*&##&%"#&+(*$)"#)+'$'*%$("(('(')+&)""#+"
@r1045
GACATTGATTCNGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAA
+
$@-)*D!,G2;5;/.5#5@?BG%B54(,+:#!2<>BA?<27>;,B8/4+?&1'3
@r1046
NGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATTCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAG
+
#A/0%H5"!F77D#;/3@E.%/'5%%69($/&++3!E$="H".$H=8B.GB,B(90#;6B=03D&D:<?$9,@D"+5(?D<=F2B:;2>C=C!#>BG;B:,;'&,0$,#$GB/%#.
@r1047
TTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTNCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTNTGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGC
+
CE7>)44493",F(;"=4427A:D*D@BH'A61>4E(7G%7FG3AEH174H890762F.1('('.>"$1#*9@1E$A1H:8=!8>CG%49&,$-15.7-#93C**&.24C"!?3+3.B+++2C474>/'*H-"@6-%9;8)(4>C!G71+,BCAF$E+'4G-'FA+='0*41@=H"'8168')5=-B@?&$E&2'H(!=9+%HG&5?799>',5&0A16.:0BF4?B"+
@r1048
GTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATT
+
*28';"@/'C161;2C$7>%+>C$(+%;:*$.#!@<6D<@
@r1049
CNCCTCTGGCGGTGATAATGGTTGCATGTAGTAAGGAGGTTGTATGGAACAAC
+
!%0@8D@>"0:<>D3.C+F(?0(#G@G=1@+"(5+:D?!=@+A/&5%+=488=
@r1050
TGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGGTGTGGCGGGTTATGATGAACTTGCTG
+
<-G$$/>C<%89:@(=G=%"%,@FB('A,#H3(D29&.;-.2HA7#488.*5+E4=+H+,D,-4*+=8D9;=)
@r1051
NTAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTTCAGGCTCGCCAGCA
+
!8&/1%<96)>%2@1*5@A4>FBDC5;A$G40F;%$8%6=!0$?)C):'CC</H541/#-7*G>'70+3C)&!-?
@r1052
AAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGG
+
#2'%/@&0=34+B4>;&(A7;3$&7$=:08F#5G@)&.<7
@r1053
TCCCGACGATATGATCCTGATGTAGCTGGATGGCGTTGGCGGC
+
$#33"##<GA;E(%'"&E7&D%E("?1B<)H&2/@5*-'H,D(
@r1054
ACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAG
+
;A'.B)&1+C584A::/>CC<9'#/613>"B:3+'@$"=?4==/@@/==#&9=%"@=$F?/H=G=,B&
@r1055
GTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTANTCCTCTGCATCCGGCGTG
+
,5C-(A6B(#G39>8?:"4E*)'@$A5:/C/17''6-19$;7D&D),;>80C!B;DD,D6<E"DA=#7!D:F%4B9.01:B
@r1056
ACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTTTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGACCAGCACGGCAGACGAAGGGGACGGT
+
18-CC"A!*=@425&%5+%F<C=H1DA=76%C#)@-"+C81A%.'5$$;3F@@2)D3C(;>(63#C''9)%0#8$!!&,;77(#=H3).')F@;3>$>@600'#*=A>D>3D?*2%-?4#:$$'-B
@r1057
ANTAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGNCACCTTATGTTCTATACATGCAA
+
<2%?#%BC5D$.04,&$8444'<&#"F761C+$>&+'0!=?)6/;/8+D",6)">50#D%)&**9@5DH(%6,7%E">C@7(;%08*.)3
@r1058
TCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCAT
+
A-0C*75:)/2:9':*?':*2H%8?=@A$-8%?E+H')%)C7$%,8<$50G)87&;<.%"DHD72$A3-!;
@r1059
TCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATATGAATATACAAATAATTGGAG
+
125/1D*F>A8"#.!3%.8*;</,784'+4.%7C4=7$;+EB;%/-#D'.120B0%*@)"'GD=CA2!G9238D"3%@(%0#:-#
@r1060
GTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGNTATCCCGGTCCT
+
%-908%#G"&(BE@":8<@F8$;0!"3<4E@9&D2#=('7-:D,#+65CG93.)%#35.G+GC/;<B>#'&$(EG:'%E/)$#A#/
@r1061
NTATGAGGCCGGAGATATTTTAACGGAACATTATCTATCAGAAAAAG
+
"$*$)+&#!*)"(!))'")"+$)+$(#%%%(#!&$%+$$'*$!!"('
@r1062
GCGAAACAAAAACGGGGTTTACCTTACCGAACTCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGANGANCCGCTTCCCGGTGCCGTTCACTTCCCGCATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCGGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGA
+
+37<.*?)7<E@$35/<*@.@-<#E(!-)6G)@63/@"*G@.4"F5,2D*=97'F9EB3/>,5.A@,,>+.*)8)>CG$4%6E+&%G-*&'*4DG*@)A?>6+?!/A)457?3&"&01>!?=?(."5D;"1%G5'#7--FA!#H;7B::@)(2E-4,12$>6AG,3;4$$F11$1$GF%:B$=G!/#AG#*D*!?G:.3F/3A<!A
@r1063
TTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGATTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGA
+
;H.F)%;E)HAC<>:7GE8/GF)E1<$6'4#@#1;%GG693A'B+C*;*+:*'B<F,318%?01@H=5>.?9A?:0:#+&H-:<7A*$450@085&3;=G0CG2*9BF8'!59<>+;<0H(>:&=C;E?)<E(3:6)2@!CH2"H5F-%$+6DBH*8!9GC$C1&%H3C0
@r1064
NNTAAACNNNACGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGG
+
)!(*$''$!$#+!%"''"+$+%"!)&($+++())"$)'&&%%%&#+
@r1065
CTGCGCGAGTGGCAGCGACATGGTTTNTTGTTATATGGCCTTCAGC
+
34%3F)A1HE<0E7G)@9=<(37<>#-#=2+7F(*1?E;2-=5@HF
@r1066
CACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCG
+
C.->#@F0&7&3',!D:B1GC(*$A";FA<*++FG3G?*'H?,D$4D=2-,3+7+F/'6.>7*ADF+C)'6?G10!/&:,?/+$A=E@A9F3:486EGBH"@F81)-6('
@r1067
CACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGT
+
41#<D?#3*%A26?&>H#80HDC@GA&==)$."7((<3-58@$'D3=F$CG7(4?(H">4/%08B3*G+@,1E*9?DB>$GA-A2/D51%B-D0$G41-D+G8G:?0(:?B,C/@#>0)#3&?>8%.:>B:G>:BCF6=F10!<H?%)=F<544.EG2<-93H;84B=)&+.2(>3>F,B29<3E+A7:-H?,?1(BA4=
@r1068
AAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTT
+
+C7D"DFH?F'2'<885@,!*>=H96@83*%(%=/*:5AAD132A0'=G,04%+E&;/4+,$H<%3A@!8/62C,'B)7%!C,C)8?,$B')H-/9B5-
@r1069
AGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGAACCGCGAAACGGTAACGCTGATGGGATTCACACCGANTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTGTTTATTATTCGCATTCACCCT
+
@"-@'-;"4D1B&G(*.F=,,&<.4>+?@G=B9$&?&$9/(3/1/5<'CG+<&9@%-F!11>=>5)2.>4<A?-"'D,7)=<G<1$=-?-@>9=8D(6%#"?,C("&!F-,"AG/AC4*2-&;GBD+B'&"&C<<+4*4H:$2;??3"15<#5-B;'$;BD=HE;$!"?1G1@(06G4::5C'G+@'FB-37,3*8C=<=,*(176/*
@r1070
NATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGANTGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACG
+
$'5'HA87:.1$D!3B=(7.@F0&E@=!)*DF)%A>F:+;4!::%&657605#=6!>3/24>6+@028.#=-<5/?$2,2C)>"534@=-@,5-)@!0'4E*42F6F)*$8C$?-*A',CD6H'?<A2/1CD<F3AH:.C"C(=;?F<$=89<'E=:84@</,C:#42:6:;33,C$>"2F:3F)H:3D.H8294B3/?HAEGC9,3!
@r1071
ANATCTTCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCG
+
$$(#"$$++)!$$"#!&((#'&+'+!(#"%$*++#$"('''&)#)!$""%"")'!$+(&#
@r1072
ATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCG
+
=(@,?<5-=844>.49.H$(629.,2>C1"$-6":6*6;:=;2,").?"5%!$6H96==1=(:A37#5
@r1073
ATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTG
+
(G#4&F)9&@-5%,'AC*6C;,<D"*;=@;)$7;/$-A,7?7++->
@r1074
NCCTAATACNAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGG
+
$***!))$(%%*+$$*"'*#"'"+)$(&$###"*)'#+#%!$('%$$$%(%('%"'%#+%)()++$!((*
@r1075
CCGGTNGTTCCCCAGCGCCAGTTGCGTGAAGCGGTNTGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGNCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTTACGCCATTCACCACCTTCNGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGT
+
&)#"'#+)"&$%"%!*)%*!(#+!"#!$%&*!++""#+%+'&*+'*!)$())"%$'!!!!"*)'#&("&#*((')*!*"!%"$)$&!)')(!%''((*"$(*$&*$%!&"+''"%$(%+!&#+(%)")$!!")+%"&&&(+%()!&(%&$#+'#!'+"!+*"$!+*("**(*#&#($&%$)!)
@r1076
CAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCNCATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTC
+
75%<33FA%-1G/'@(@H@6<?>)E+5$0#$$70&9*$)#:D7D)!30G?*6@AG46'*DG29E1E>**H1(.#HH*7+?1?>36D/%:7;:5!>2@A82>?=+F+,C@77/H@F%0<<C=A=7!.
@r1077
ATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATG
+
=!1255:@%@5*?A6;!@G,8#?A<$E'5=<"?B/.6H!AD544*1%2
@r1078
GGCGCCCNTNGNTNNGTCANTTGGATGAGTCNCATGGGGNGTGN
+
((#$(&#!#&)"#""&($&!''!"&*#()*(*)(%'!"'(*'%!
@r1079
TTCCCTATCCTTCACCCAGNCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACC
+
(4?#(*EDHF<6#/18;.D#/*2$6H1("C<8'?856#.8+C3G5)??.2AEAD1,=FC63?)7+G=@,#>%CAG6@@C0,*6;+*+
@r1080
TGNCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCTA
+
B4,0:%CG/4@/%H1>&?@%B$*-F!H=6@"=;"'HE.7+=B.>?4H86,HA!:)93)-#@9"*7+,=B(+9"-1$/,FH*8&,<
@r1081
AGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGNGATGGC
+
9!9H<A8G6?91:3'75*.#>5<?@CG4#!,!C@(@3.3A<DH!(D7"$,-"E?+9.5/7#2#$<B&.=@:D&B.C'7.<H3E*2B<CC?4!5
@r1082
ACNANATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATA
+
)'%%+"("*&$''!(!)#)#+'#$!(#&%)'$&$#%'&"!)+)$!+)#'''
@r1083
AGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAG
+
.6:C'$%$>F*E=?E+7<!">(F;,G><:,);!<E)-7260$2@+?:3>4":%)$8075F5A#0:6,#D="8??-F,<=:
@r1084
ATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATT
+
/G:D;79.8D6.(?C4H%B+-2<49G24&B(-FD791!5!'0$+
@r1085
ACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATT
+
B=1:=.@D)AD176/2/>83A)G/D7-;.:2H2:3G;:+&&@/6#1*3:B2242
@r1086
TTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACNGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTAAAGCAATTTCAAGCGACTTAAATGC
+
<%%'$)E)D.#@,70,?5H5/;:0(:C.EH,<1/0<=($!H(3,8:&!0&;&H+4C;%//7?#$1H&E&71C(A+78&#3@GAA@@$6E''%,D51"H"A(&9C>><F"(B>;/<<)>)/.
@r1087
CGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCNACTATCAGGCAG
+
&CB#5'0$+@4',$):9#2)+;<H9<;0F$?)"+9,(2/:@4A,/7GD#/<)//)5;"#9-&<#&&15AG'#.%*$4#075:9*0$4)$>3(B-)"?#
@r1088
TGTTGGTTGGGGTAAGCGCAAGACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAANTCACGAGTAGAAAGCGCA
+
?(;DA6?9+1.;"!G-D76>6BD)/F/50?C(:D"#)75,)09CE+BG!4FD0//A?D(8!;#2)#&@AB58@C=+.0>1D#,
@r1089
GTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGC
+
C*--%;0E*<,%/45&57F2!:4*.0>@=97!38*33:?(!('F.2A@534E
@r1090
TNATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATG
+
@&!6$28+,.:8AD@5(D"28*8?!25,*%4!8:95*(D(>&D&/2-)-H0A/6361$*
@r1091
GGTCAGGAAGGATGGCCTCCAATGGATGGTATNGAAGGAATAAGAATTACCGATATC
+
;%4,E@?$)?-,8:3B(6*CG=687.!5%+@!+.-0:;@<>7<1=4:042DC07HE5
@r1092
TCTCAGTGTNNCANAGACGANNANGGTGCTAGATNCCANANATGAAACTGCCGGTCANGACACCCCTCTCAGCCGGGAAAATGTGCTG
+
(%%*#)(*&$(()%%*%%#(!!"!)&"##$!$$#")$*"&+*#%$*$*%++%)#*&*$*&#(#+*&*'%*##"++%'+&##+%$%%)(
@r1093
ANTNAANTCAAAATTGTTGTTTTACCACACCNATTCCGCCCGNTAAAAGCATGAATGTTCGTGCTGGG
+
%%(""%%)(''+))'("$#'+$*''""&###%*!!()%)('"((*)("+"!#+%*((%&(&!%$!()!
@r1094
GGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTT
+
#="(B%A00)6!76FH3'+H'E.8"2FCEA:HD?C70+F></4+F-('3+%6%+%-:+D?;04@8<'G.)115052)<.
@r1095
CNATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAA
+
$$')+((+('(+#!$*+$+*!#+!&+$()!"%%%%!(%##)+'$"#*##$"*()$+(&'&&%&*()$+'"!)"'")'*!)()$"#'+(!"&%$)!+&&
@r1096
NGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGG
+
%'+<0C,#?0>"+@H*D4-H05>2=D<-<E?'!C#-."D;D3
@r1097
TNAGTCCGGCTTCTANCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCAGAGCCTATCCAGTCGC
+
"")'&)#")("'*()%++"#!''$%)*&$*(&"*+%#*'*+#)!&$%*%)%&%!++$&$+')()(!*&#&)!%#++())%""&"
@r1098
ACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTAGACTTTTTCCAGCAGCTCCTTG
+
:G<G%E9;E?*6(D.E#%282&$?)'!54'9?G8@6%<7F+GB"EFH+(#G$%7.,!/7
@r1099
TTCTGNCTGTTCTGCACGGGGAAATGCGCGTGGGGTCNCGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGA
+
++&'('!())""%"$!%!$!#&&&$"*!*)%(!*+*&)%("!!!##%%'$(""%(&!*#!(%%&+*!"+()$&
@r1100
NTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGGG
+
*#())EE0D:8DC3+&%;CB.1)@DB3C?,E!46BD'0-03DAE5C'9B
@r1101
ANTAATNTCNATTNNTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACT
+
("(*$(!$%"(%&%+"(&!!*&!#!'+(*%(+%(!!%*(!!(')($)!(*&%&#$!%%
@r1102
CAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAAC
+
>.C+&H%7!(+'):F,3@<A%;?,(:':G#23AAC5"?GC$>D&($D=4*92/F;"H),9+C"(8:0@6D:A5D(5>5*?;>38B2C>HG-'G,-@+5$F$D47+8@%&+F337A'%!.(?=5B6(7B-?/CF+.1/>@;2C6>8D)$>.A#!?E<1..68.;5C*E?H,*.@<+;+7C1'B4&=:9C4H,<#$65:2!1-E<03A8@F1!,1-=2E7*";AG**=>&#+=!H-6?G4/
@r1103
AAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTG
+
@6&D;G-C<D"':47G$0&%5$#8*%1@?#9-AED;4';!&F3"(0D+*'D
@r1104
CCTGGGTNCAGATTGTGAAAGGCTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGT
+
0!#5-'!D=H6+%&GE&:F"1>%@/HEE(7'4%=&<<A*)*4AA8;=A387@13*63.8(5??)(.F
@r1105
TGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTA
+
3*<'G$90==F4AH>FD<<6!<E5"*/<4*0:.""4A=:4=8-;C=*)DFA5
@r1106
CGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTT
+
(HA=B)BF3HD<$GC)6C1?D.04DG'8."5B=?!.E,4@!$/:4.$C%<#<03B,>52/&
@r1107
GATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTAGTGCTAAACTGGAAAGCAACGAAGTCTGTGAAGAAGGNAACCAGTTTCTTGTTGTTCGCCATCCTG
+
G?)A,F&(>)+-!@&3;31',%*6G#><='ED70#4*!>G-6:B)D-4)>&D;.CE9)/*(*H<AG=/#+,=:894)F<2<*5F,1!+5=A)7+**/(7"F"34>1B#(&.9/HC<%(+E,,?:(8DEB)H?01BCEDA(39$.$C(E*%B>8>*;B?(&C4,2!49CCH887FB=B(6B:7A@3),+D?41A&)"F*7='("&*)F7)C2,'D<:.$'</@53:"B0FB)5+HA))A#3-.<!)8:0!$@
@r1108
NTACGGTGAGCGGTATATCCCAGAACNTCACAACTTCCCTGACAAACCGAAATGTCATTGGATNTTCACAAC
+
#?195A#96<CB;0&<6ED?F*4G06*7E"%2:<F2F>>'4172*$F"%'9.-*=/6@'9:0(D&GH(?36-
@r1109
TATGGAGTGCGACGGGTTTGATGACACAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTG
+
,"AH#-8+5.H:+BG0:6,GG(C!E@$')<$H8>>/5+-+(>,6G6D+F<=-5(CA$DC&*=5?9A+4=185A'6"1??2<H).5$<E!HC-9&H40<*6/-5
@r1110
GCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTC
+
;B75-$$$7:4&$9C%37A/&#:;E0;$%/6<,4B"4<07<.&03(&2&5A&2?6F+C'"C*@/C()2?:
@r1111
NCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACC
+
"384E-5%?7E*:+C23.;C56+(G!@-&7<;<$=+0)H4:.(2+E("C;-@5."F6#F'2@/*=;>=/%A4.8-%%-
@r1112
CANNNGCNGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCNCTGACCNGAACGC
+
)'#"'%&!)&++(#$!#$#()+"))'(&+!)++%$(!!('+!&)!""+%%$(+))(%++%"#&!#")**&(%%%
@r1113
CAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGC
+
&,><>E'*;0=E!H;5?*@G'29!><2"5B&#*&8HD%?/#,H0&7%$<-&EAEA;+$%<*A6
@r1114
CTGGATATTGGTCGTCCTGATACCGCNCAGGAGATGCTGATTAAGGCAGAGGCTGCGAATAAGAANGCAGACGACATCTGGAA
+
<E-A2#8.&060<7G9A#9G#)<E/;&/<<0,/0,BAH:*A7(4HG%)96B=30@('!B09A!'2-*H;#=3#68C?E!##7$
@r1115
NCNACNATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATAC
+
'!"(+)&!&%##&"#((*&$&(+)*%*'"$(!!#%)'!*"+(!($"!('(!++*$!"&++)+*$)(&&!!)++*+!(+!'())%&&#%*(!#"'!'$%%)"++')#*&$%'&#((+&
@r1116
AACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTNCTGCTCCTCTCGTCGTCGT
+
%'(+*%#&(*%)')++**(#)**)*(+($$+%#(*'&"'*+(&"*$&$&"%&&'"+%&)+*(%!!**%*&+
@r1117
GGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATT
+
A%2>H>'?.!:9G5%9>(-#:;9,D&E5,/.3HE*11>F0G-2<F%)'
@r1118
ATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTA
+
-*"*0&..A(9>".?(!8>:(GF41%;!*=.(.86D#!-$2G--"HF'H'/(&$./31>DH4-+6C1'"6D>B=%=@B7#"H1?.-09
@r1119
CCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATNGCCCGGTTTGNTATTGATACTGGCGGCT
+
9A)D>6+9=0):5H(E;FH"#B239+&A+<D)8A.&%E++-80*#:::;,7H'#B860D02(=A'8<9$**EG;#(?9-4A&*:8.;-?<@;B<>2/'F,FE837/G8.3+6"05;(<.(;&G$6=,;
@r1120
ATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCNCTTNCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGANAACTTCCGCCATCATCCGGCGAAACCCNATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAA
+
GH74>A+$,@.)9A=@$2!2F*+DC,0/:=.'-""#C2?:<$!9<007$9A0*#D?+3?.!6>,<%").;$!=<:+D/B'#,C%0663;+G3#D)60&3AC58!7/C+EF=*+'#-:*<$.,*-$3%.#0A?/F846!FE@H?$C#!A69<(>0.<4>G)C((E9A,!&.5$4.E;$;+#>!878%D&C*,(*$A;B;D.(8@6H4$><8";5?9GC'4*E''1>=%$B65H@:6>CF8!&AC8A3=%'E<!#)@(+$!A-7+8)&/6)!#++171@)-CH?=(=>C+19D.?3%'@$@8*&*<,72-*10942$7.%E129>&1G$13/>1%;'*@#5F+'G?"0G-(40/#6&
@r1121
TGNTTCATCGCGCATGGAGTGAAAGAGATGCGCTATTACGAAAAAANTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACG
+
*&!+)&!("+'%$(##+*&!"+#)'%%'%!#)%$)#%**##*""%$"%'$*$'("'(%%"(!)!)"#%#$$!)&('!"()(%*$##!")'*&&!&"$
@r1122
TGACCTGACANAGGTTAANTTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAG
+
(!%))+$$)%!")$"%"")+"&+"&("*!"*'$)'+"*("!+($*&+'*($")&$$+%%*$#+*$#&'(
@r1123
GCAGCCAGTCTTCCGGCGACATACCGAAATAGCCTCCGGCTC
+
:9=F*G-C%'5079#D:->=42DA=6+'C,0%!38D@#,*#D
@r1124
GTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTT
+
#EH9>3)!"38*")<G"229?HH2(+$<!"&$(16?=355"H-<2;$;1D<9.>,)01F6%)/1F?
@r1125
GCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAGAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCNCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATAT
+
)+#'#'($!!!'(!&'!$$$'++$"+&($($+(*+'*'&'%+!(+'&##"+#''$&%'#'!+%!!$)%"*%%+'*$)*##&#*"!#(**$'%!%(%$+)!)&$&#)('+!(#)&$$'"*&!$%&!#)'$(*+!'%&!&"!#$'$"#"&)$$"+*"#"+('%'!+$+$*#(((&+((&"(#*$)#$$$")('"%%$*%&&##!*)$*""
@r1126
CCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGNCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGA
+
C1G$F3)=1?/FF$A*49GC?.582=F):5)0?.!9>.8-)4E*A0+F4C"#7!,30?"654$?71BD;+$FG?5$,<6E#6A!).F@H25*.B$(*:G?!+09D,4,?1$/3')>&=16#94,E;&1:)6B%#-%/B'#C5A-?-<8>DDBE*8+4F*52C!$5BE2;#=*:97"84@=>HE1:!:G&ABDCFDAA0:?>:+##<C*$H*
@r1127
CCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTG
+
8@58@G924<81":H&!F+:G?B'D./:0$/3GF.'C;1FC+/8$.#7)'@8!,C>
@r1128
CGTGGCTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATNATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACA
+
0GC15-GH"@=8B%3FF2)<."'$B=,@9GF6E@3=14(+7:/FD!,+78/:20-+A(%A6%*?%4.-G<0>:(%,1%)#6:%
@r1129
CGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGNAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGNTGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGGTGTAAAAACGATGAATGCCGGGAATGGTTNCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAA
+
*EFB"'>:1='76):!*?D5-$59E7)/+8F**71.+7EH,'*C&0H&0&+,+E)%+<":G)1C-$8=%A++A9#;6=<?12*&:+G"5?0F4&C-:?"3$A5=&9>G9$3'A6!B6$/,7;?(&##&'1)>("(?D!?<(.5)>>C560/C2@@H'8"+1+H5;4E0=3(2=;01)H)%-'BA;5-:E7'*97G?0<(@A)0D/&C)6B,4<8,<+EF<8'BG!'/7B+/9-/9>#&E.4?$1H'AD02E>-8G58
@r1130
CATGCTTGGAACTCAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTNGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTC
+
+;#(6FH=:5642"45D":$=>2!0GF;(##/H!4'6=27+*3(8$,+G-A)$4H90=-/%.G73)0>'43*F39+C.F6+2'>!#'6E0*E5?)(-9?'-(E.<*:7F?4!-H<;6/34H+BF<6'8"C,.!?&)4%4#9>=@-0=-"7H?*6>C8@-E<,)4G";2D)@?<;4A6F>H.<A@=#%':<0'>@8@HD(38@&1+B+3!A:E%/1$2CG)(%!@.F-CA@@#G'D2
@r1131
GTCTGCAAAATGCAATCACGANACAGTTCNCAGTTAATAGTTAGAGCCTGCATAACGGTTTCGGGATNTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGANTCGGCGAGCCTCGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAA
+
,G<#(F+79&8,)(C##CG4/-C"E7,AG=74<?/,(C4!%A0('92%D**:&A%B");6'&7BF6$),*98+"?<!$;AC3#HB5B?+#<:59$<F=G4!1@-=A$E';4'6.&@HH>&1"@D>6%B$$-%BH""@1$""=AGD-E%%1,+<4HB("(<?0>;
@r1132
CGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATNACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCA
+
"%21:!5C6C1!6.9+.$'+?;$<;E@C#</<D<():60,8GH"&#?@;<*3-*3)41@57&0H6F!1%8=BA.619;=#>))4'0+*'.B$8="=F@(<</5$55B
@r1133
GCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGNCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTA
+
#9<F,F.&1&@A;88"<<27H($E'/0/:4%+30@*7"!A3';$60D!(E1!89$";E3,D72&@0<58BG2-!*#=5<0&(C*&9H<%'"B20E39>,,0(,)+-734.!GCA*2C=9(/'B"A
@r1134
NCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGA
+
%7#$#2>!?D1%G="<'DC"2+H:**)!C<D72FB)917878@*)#*4:#HG-:C488F&1342G(6./G6F820A6(G;G+.2!5"&507.#$."<>=3<(*,'H6&FD3;8B-)GH3'+<(#(,7F@$E77A1(3+F*>!;D)4;9&9%A<DFDCE+(9G@*2%
@r1135
TTTGCTCCATTAGCCAGAGCANATANGCTGACGTCCTGCCACCGGNGANACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTAGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCNCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCA
+
?:EG?B"4>92A$'870H+-GH28!,%3>F7DGCB+";<*5?7E**.H12H=(9*3$A8@)/*54906/6D<'.)==GDBCE)>,$0>8HF5HA2C>&!.#$8DH*7C!(=*#FH5H;C="(,3.:5%4G%-%6+0%EA>'8@)*4"3EH8;CG(882(,F7D01@H@#G$?.9533G47%6BC8"=56E#3(>7:<&93,*,/5.8!%H<8DB+B*="G)=;.)!-E.#-9B'!F"4
@r1136
NGAGGTGATCACCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCAC
+
$+#'&%)$&#!*($''#&"#"+&%%(*$#%)"+*)$")&*+"!"#)*)""!"(!"%%!%%##()###$)+%+"%#
@r1137
NAGGGTTTGTTNTTATATGGCCTCCAGCTATTGCCTCTCGGAA
+
!"+(#&#!&%*(!!*(*%!%$$)#(""!)"!"'#&()"''%)#
@r1138
CATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTNTAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAATCTGCA
+
0(<G1/@!5$"7!E@F%0"<DED#=3G>>0%"=+3A#F2"G8A3D9)%,/'0:@(7F*6F)75E0%>D36D<1@"5&!?@
@r1139
AGTAACATGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGATGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTG
+
!/&)'BCG.B@F,E2A8>D@D&H=H)F*G,@H5,<*6;$%B$F7G+-*F6/.,/),2:E2%21$(4!(7("2%#D6$A:2-8D:-39;514%=*30BAGD(!9=!='480,/EA")EE%3C?(2'9?("1GA'<A0C1'A?&$-H.93.H?0C+4F3,'95/7"55311@403'HE'!;+!-=6'@>-3/#1'8"=B=32F*B00!(D/,E"2EE
@r1140
NGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCAT
+
)>40,C!5G)*$.5+A0)F:%&#CC"9/E+.E%"GAHG*%#$,E,02;@=2)"?!D+F(D:!)92<0
@r1141
ANTACNCCATGACCGGTGAAGCCTNCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGT
+
/G5!<BH=->D(/DD18<E.97C=1$)AB<G(*5F*/=0>E@84'4':99D4@;58H'(01-3C-4?>*(D6#6#@'4
@r1142
TTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGNGACGCTCAGTAATGTGACGATAGCTGAAAACCG
+
,BE:G@BA,:>=H3$%-1'6%*06<?E,9-;7<18E#D3C;B6+%95A;)"#G!'A08-4G3<FD7F6;G?$EH,EC9(@<CH+C%6,4&HH""==8/@8,@&"8(F
@r1143
GCTTCAGGATGCTGCAGATCNGGAAATTGCAACGAAGGNAGAAACCTCGTTGCCGGAAGCCTGGAAGAAGTATCGGGTCTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCATGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAAC
+
)+36H('3889DA)$<#9"<6/24-B)(,*-'@)"836.-#HG"-#7/D50:?#.2H2>E:)9'81$86(1,/B%(8)4E7-2(5(0323A!)&@BF*GD,8<(HC'=7>4)D%7)2)4.-..=(8,B9#(E!@5*.#H<),+%;+A1EE%GF7C(75E+7!=/88-F?15%#
@r1144
TTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACC
+
0&H+!C@);583#?39#()')G!&??F-@+=6<<H%2C:@>D?D
@r1145
TTANGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCNATG
+
&&*!#$+')('#*%&%$$&&'((((*('(#"(&$%&"$((!($%##)(*$++%"+'(+#+$#$#!&$&##(&&+!%)('*'!"*))#*)!"$*$&(+"&)+*("%#*)*&#$"$#*"&!)'#%&$*($*&)"&''!*%#+'&%$%+"&')$'+%&
@r1146
TTCAGANGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATANC
+
3!*-$%<:(?5D8=F7/6<7...C*(8B9$%.&@54*(>62#E$C(6-$@1'@"3:.&FDF'7><<?<CA$>-:*!D,>=?17.+:042=!EB)(H
@r1147
CACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTA
+
91C?$./H$-&9F9=*0/ED+.C6.D..?@9$.7+E?)"$;,%8#;&@!9648
@r1148
ANTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTG
+
!"4ED&8,*.>44?34284=%7C/D7?*F*6BD1,"+$D7B
@r1149
NGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCNAATGTTGTATTGANTAAATCAATTGGATGNAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTC
+
&"+"("#'!""'&("++*""!%*!&#)!*(#(%+'!&#++&&%#($!$)"!&+("+%#"+))&"'#"%#+!(!$#$*!(++!$!**!&*'""!'"+++&!!$#")(%*++"')%!&)(+&*#'("!")''%#&)$%'"'#*'
@r1150
GGCGGACTTCCGACGGATTCCTGTCACCCNTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTA
+
9H"#!9DEG=>3@D<(D!?E3='H%G40/G>&AFD?8GB$3<@#*9+:6A*4BG8H)E1FG%GB(-*!
@r1151
NTCNAGANATCNGGGATAACAGAAAGGCCCGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTA
+
"&%$)***')")!+#&#*+#$&)*#*'"!$#)("$$#$$'')%%&*$$'(#$&!'))(%*'(*'*%&'$")$&#!'%#++&*
@r1152
TAGTGTTTACATCACCGCCAATTGNTTTTAAGACTTAACGCATGAAATATGGTTTTTCGTCATGTTTTG
+
/?#.AAD,0#%C<F=24@F&88$0&%3.&F#27-5@23:@(AC)>/7#,HGGF7=C)>)*6#G4-',:#
@r1153
GNATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTAT
+
$*+'!&%#$(+&&%*"((&'#%+#*$(%)'$)$"""*'&'#'#)
@r1154
TTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGNAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGNTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCNGCAACCGCAGCAAACTCACCATTACCGGA
+
%GG5"(F8;=G4.%,DB(<$,B8C<17HBD>(0'(99<5DA<A&A'43:)"B#%>8:+D10%9;16/0+E5-2(H#=A5G30(4=024;2)5FH<8?&#AC+1.E6&0-#85C6("?-E/&?:,72"2,0+-09!.?;0,FC?74,1B*#H!,5#$9,DB*1&7"3-+,3!$?94G7A5)?<>BC+!9A+B-&?):'G)%'?29/19,-D>?84-<7?D$2&(HC6(!:0.6*;!$C."&!G-A*,"$5--02>?H:EB,D;@0/;GFB-"@>7$@)C;37-!54,EF
@r1155
TGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTANACAGATTAATCCGGCAGCGTCCGTCGTTGCTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGT
+
H7>HH4-9;!>$#@A8D/CBEB)FF>/D,2A>E,6D2E=3>+.;D9.D@H-.2#)D!B('0C!,$2$3FC$*6CG4<;4'E#6'C/5+.F<@@0+F:0(7<!6F::E-(7!3#+C%E4<1&'$=)06(@(&1C'F&@0>07<-A"=0-HH9$51:D(E3HB:#$/!E;
@r1156
GCCAAAANGCCTCGNCCNGTTAACCTAACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGC
+
#!(&)&%"&*#%$!"*'"$''')&"&"+"&#)*)!&"%%('')$#(!!&)+'&+"+)&#")+&!)!#(&&$(!"&&""(
@r1157
ACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTNCACGGCANGGGCCAGTGCGAACGAGNCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGT
+
=>78C@$02*5F*+;C*%D%/?BC1G8;)66D%=?F)!8)9!E*G;H9,8E13**:156@BG.D&CD:016G3E/&2C>42<0*$":8%'3%?'A<+=D-3A43&.D=BF%6DC18H*)#%4H*>.&>CFA-%6@&17G:+.-%:63=0!!'%;+":>@><=DC7727:<D-#2#8C!C#$F8F45E:37F=0:C9H-B)%%3:=%!.B0H
@r1158
TGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCC
+
0C/6:3'@%@F0=E16,E=@)+EB.&HC5)/7D80/58!&H5:
@r1159
AGCACGGCAGAAACTGCCTGCANCTCTTCGACCTGAGCAATGGCCAGCT
+
=HF.1?7E"C>*<3F;B6"FHG9=;58C<-,?:(/1;B,2,?B$&;5C1
@r1160
AGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCA
+
B)=AG1<*9:0H&6>A@(E@=;:8&B;,@C-@%B,;/7):2?-!.@',.AG1##6C;+-H'3,C02'!;0&4G*+%8!,%H:2(2<&+@G
@r1161
TGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAANTACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGC
+
:E7/2,%G:CF-/50-B1'94*69;G0=/2##==96+A6793&G13-3FD?18(.$F69/09-B0'%<7B91%<@-7#80-DA5'&(9B41.*?(8&<G*H?B"74=AAF1"'7!5H;"98<=G';4!C/H&F>3<)D.>31'<$:!:C#
@r1162
TTCTGCGCCTCTTCGGTATATTTCAGCNGTGACGNTTCGGTATCGCTC
+
?5?::8D/6H(?=,--(<2D9@;)<(&$"B)F4;AG&<4*/0GE('@0
@r1163
GAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTG
+
#-4+B).*F1?%@31B;C&$G)&4G0'6*":=#03A)'B/B$1,99D->5)7&8G1$6GE&):=);
@r1164
CCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTATCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGA
+
?045(D;@1/")H=,4@%GC72)!)A8F"5*;'&!:"%08B'>4)$,;!257.E#?-!5C5A,6/$@B>?,AE.%%H.&#@/H0H#45)?%*$704:(89>;/D)5H>)C=97)0+76!"86*#%5"6-52-1D(.(@(24/
@r1165
CAGNCAGNTCNNTTATGTTGACTTCCATTGTTCATTCCACGGACAAAAACAG
+
)'%$$"&%!)(!)%%(+$%*#""'*+%&(%$)'(*"%*"+"*'")+*&!*)'
@r1166
ATTTTAATAAAATTAAGGGTTACTATAAGTTGGAGTCTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTT
+
A.".E1GD#:#15?:(&4/<E(C0$7B;A;00C0H3<%.+;>30H&#;7;)$,?8E$*,68':>96/$*D,>&C6/G2GC81>6/=@+F6:'20+5-"99!:"$C"*-(?;/E;47:%C)#1-A48C")D#5H@&?C@FFH;6E&28;)""3
@r1167
GCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCG
+
'G=H'9/-/-/<E"*3&-A7*<7/$F!(,:FCE?@;<"=B33&&EA@4.+@G1&=@+B6$H9E*;D"=+C,9*C@?EE'--,$.5B91!6>A9/)90:#%A%A=9;D'C-"20$
@r1168
CCCCCATCTTCGTAACATTACGACGGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCNGCCGTTGTTCNGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTNAAGCTGTAGCGGAANGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCT
+
##%+*)&!#)$'$+%'%%$)%!!!'#"%%'&"!+("($($#)('('&"*##$(&*)($'*(""*'&$&*('''$$*$#)$#&%(#&'*#+*'$$)%+!!+&""#""%#+++*$*"(((&&%(*#)(#!#*'#*!+$'$*&%%&$*+)+")%#(&+&!$)!"&")')&%''&#*+'*"&+#%)$++%&+%"!))##!#+$&&(%#&(&$)("!&&*'!#(%*$
@r1169
TGACATCACGGNTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCANCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCNCCGAAGGGCCATGAT
+
698?38.5B/5F)16*&2%=3B60&06G>D&8>1'F$3E+H5;9*,7-H35(2/%9,$&D;2@>G,2@'541!=(898G5>#;@:!E,44<F-%AB0C%."<'*A>B
@r1170
NNTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCNCACCGACTCATTTAAGCCTGGCAANCGGCATGTTAAACGGCGTCTTTAAGG
+
""*2@).C2@3*D8(@,67+&0"507(;8)3-);.#+83#3%+9$/.)7/3'9,"$<7:5.*(7>%/F,AFE$1-4;5'>D0824$ABG:4#B*H&-=%5D'&D'.)"7"H%AD)D;*6382+:$G=(,D"
@r1171
GATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCANGANTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGAATAGAGAGT
+
0--H#.7%5("2#H'66C=A#-G':6<5HC"85?AG()"9CE+4.22FEGE16!2E"!@.<+=F9G>&0C7!45$;.1&F""")1$@7D!A96<)H(4*4;2AHDDDC@;'2EC<
@r1172
CCGATGCTTTTTGANGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATAGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGGGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTNTGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGANTTCTCGTGATTTCA
+
EE(+A,(1DH!/-6@G$3>1#@*,9>%!8,";?4H7/#2!'#/4'&>30E/C3&2&9CDG@19F40"(2!0DC,CEDA)@="#+-GE=B'2&'1@'7;=9&$81/>+F"3'&'"F(;:1&3/BC93#4H(G#==-H3-C%*G6,DH:H*A#4&$C<;,"4!+8,>4<G#81%EE+D56E9$*&&4'FBA'/0C=67;(3"23;"&@<7691F;&$.1;C/6*DB-&:5/3+4$##9$DB?"0B)6/@,/=D<B-(&)G--,B-DD.>"9=-)0.B#1,,2%.>:/D9H$0:9.0B5,*H//&>..8$7?-6.;;?>-5=<-.8F66</6.#C&CD)&'FEH-8?7-#'@<D"<-591?CC?E$@@E49F?8%A9E+6,GGCB<41G9/)0'H7?7G();**.9(7;)!/E&F$C*F4E!3:(=1"2$(E-G39$G85<&&").9FA.H=
@r1173
AGGAATATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGA
+
EA!#E!=2=?6?//?HAE&0G(E8$@"'F2(.EG8.A16:>'0-91(<5!':F#/)F!/1F7-0D,=(G&%+#.'<@3==5/=.71HG#!EE8?428@
@r1174
NTTAACATATTCAGGCCAGTTATCTGGGCTNAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTNT
+
&HF(5,0:">&&61%&/5(,,#F++'80G&)7);>E+,:@F+C).60.!""5%,'AFF@?B0.%,'&<759-;'./:<14.00E*)C=E,=B2!8<#*+0';1''6-'@>C#,430'27+2=-2)/0)071/:9794@?GD*4?#F$=$>"1874+H5AE6)1*/%H0">E0BE!G/9G,
@r1175
GTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCC
+
7HE&(1F)G&6AH#*27)G>$<.4-5'@D"*&4#(%B5,G
@r1176
NGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTTTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACNGCCACAAAGCC
+
%?"FC(1)$9.B:&&H3(FD#@7./>D#&@6E+,'/5)"-!!7D"61-%2-7'C<;DH.)07+(-@5E2GH)1)."(H)A@*G((/,5
@r1177
GAAATATTTGGGTAGTTGGCGATCTGCACGGNTGCTACACGAACCTGATGAACAAACTGGATNCGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGNTGCAGAGAACGTTGAATGCCTGGAATTAATCNCATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGANAAAGAAATTCTGG
+
+'#'())#$*"!'(*$((#!*)$+%((')#%%)'!(#!#)+%)##")+!!&(%**"$**)!*)%(#&!**"*+*!(!'))%!!'#)*&#"'+%*#'#(!*'*$)(&!'&"%#"#*)%%)'+('+#!'#(*'&+!#))+$"!*)'$+!&"%'(")(#$**"$$&+&$%!&#%**'$')!"**&$**'#"(+"*(%"'%&&'#"&$('$&!&+")&&&%('#*)%*&%((('&!#$+)"'&"$(++(*'$'+)+'*)#&&(""%#!()"!"%%!!$"(('$&+$+"+%"(#$(!(#)!%
@r1178
NCGGTATGAGGCGGAATATATGCGACACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAANTTTTATGGTCCGTG
+
"-:%6E/?$'H<H50'6)'EB4&5,8:>48A;$#>.AC;$BHD;0H'"(+D!4),$#G5B%5G)25HD@0$3GF12"F/6";+"#
@r1179
TGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGG
+
G#F1EA)0DHH!,H?G4<99-=?+4&4/'23)H?89EG&'
@r1180
TGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACT
+
=<'?)G"$/0$2.0*$1*AF>C$>72-"."356'=$C!@!*,H**4+7@0)"0!:%#>!2#4%>032*=!)$%28@2>!*>(47"D"F15
@r1181
GAATCGGTATTCCTCATGNGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGNGCCAGATATAAGCGATTTAAGCTAAGAAAACNCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCA
+
++%%"+()))%#!)(+*&&##**$#$++++('#"$'"!*%#+!)$%&%%""$++#*%&(&#(!#&"+)(%)$'!(&&*&!('+&$)+'#+)%')!!)&"$%&$')*%'')%#&*'%+*(++'*(&$'+$"$*($*(&!%$))&*$%*("*'*"'$"()"*+%)
@r1182
GGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAATGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGNAAGGACCAGCG
+
-E&+?26.(+672$9$/%4A)E!=+E;A<;0*A,+6*7E$"#?#E:B4*5<0(00"'!7,CCC?F&C$9B$9=#F0<07A$!GH+(96:&800E#*;<5.33..:H9&1C/"(!70D9@>'6'$?@7#7>"?'H4*:C%&''3?3'.E61&E4(C%H+<=#=0#!
@r1183
CGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCAGCCACTCATAAGGCGGCGTCCNCAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAG
+
*$5G!:).E39',1='<6!E;AC(5>F57F'AH--&74,/=0BF3119ACE3@&@C:A82D6A#+)%)3E$../H8:$3?A9-B1E-7215)-.%DA#,?29B8D654"8,F:DD$(*.%54!C)5@C$FH!5&A('AE#B=!%;9+G(-:");<$&5>805GE9;
@r1184
CTGGATAGGCTCCGNTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGA
+
=%#F.H;*B>'0E<D-<D2/'<#+/>$3.,+C<D3:*1;=C13*6-FB?/)/'6968*+8B((6G!B&;
@r1185
GTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCNACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGNGCATGGAGCGACAAAATGAAT
+
,>:4"8C!:.>-06-1A50:@!;@B0$6=AG"A$.+CA;:&(B)8</89!4+B.1E*'B0.::5B<B/H,2#@B@./.((39'"F)5>"-+2!H/6<#/:!#(%/1C"1D7?4A8+D?.G?4!H<6+:6&D2'&::30:H5/<
@r1186
NTTCAGGTTGGCATTCAGCCCGGCAGGCGCNCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGNCCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATAACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAAT
+
!?$1:"''#6?'1+@?+>&=GC9H0B7D0*%+3)1*@/EAD+19BHBB4A(G05('>21=,?'>C?"7=7('7>2H/G$,&?,A%DF8.9"7'+$C9@B0)GH(GC%.185+5&"'8(=EB6.$%-=-"'>$F"1"%.#D2G1&H",&C/-@&D=F/8HBG3=H+1G'?$8&G(:,/0!;.C#,'01H8(0;8%+&24(#+D8@!:@3&*+&(-D,,42&<>/(:*2=C*A1D3*F8#56G"?.@-,16'?F"!)GE.6E
@r1187
NTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATC
+
$C==9)*#E&#78==$07."B7ACGBB#"**"A.G0)4A'5H;<8E7()%,DGA(6F)@>C/468,,.04?>3$&.)CG@<<C:7#<"A=(<#:3,*<"(<
@r1188
GTACTGAAGNAGCACCGCGAAACGGTNACGCTGATGGTATTCACACC
+
B-<(.5F?D#@791B>BA5.;9D!HABH.#E>EGFF6/;FGBG6%8<
@r1189
TCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCNCGCATG
+
G:'?7@#??2#&1:,$79/AE1%41<D(?+F,):#=+;5F00E
@r1190
TCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACAT
+
9!$!<)%C-8+))5G><D(GBC#E9?!8,5@.<E:(>%(%*>5B1)4(.%,E:&>)H/74&13)&;08,EHC*:1);3?14*C4*'.1
@r1191
CATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTAC
+
=B,%$EB%'A(6.0*?"3(FC?$9+>.>)C2D3H)7>H%=85E=E!EB*C1-7)#8EE-**#==(14B<
@r1192
AANCCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCC
+
"$#+&*')&*&+)+&')(($!")''(%"'%*$"+$*%'#!"!)*()"(+'('''"*$"!*'##+#%+*'%#"*&'%+&()&)%'*#)+*'&'%&)#$($(!#*"&$**$*#$$&(
@r1193
CTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATNCACGCAGTACAGCAAAT
+
>&2AB61+=@-:F*:G@BE'D>;G/C5C.F@43D'7,?D,C70';G!0)9=:%DG2+/7:H4"H.9*3(4,)+#-2,>;C1*"9*&'9#;9,=FB:"$C,7A)F.:*2,?G8
@r1194
NTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTC
+
)5/2657;<4A?2>..AE!-)$1+4(6-@*)+&C9>./#1>!9<D#%2?=E!9H>!5GA<+&!@&4(C5!!<-+AGB+=@G:94C72=,#*2#:B>8=EA$E8C.&+.+:>E&B5*8?C>&-*1+-4<=-6
@r1195
CNAACGCGCNNNANGGCNNACANGGNNCNNNNNACCNTGNCTGGCCNNAGNGANGTNGTNNNGNNTTCCC
+
!""$$$#"#!##$"!!!"$""#"""!!$$$$###$$!$"!#!#""!!##""$#"""$$###!#####"##
@r1196
GGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGANAATACTGCA
+
F*6>/G->.9.>$H9*82/*=9751@8(&3?F!C)!%#+AG<6*%D*#7:6'$/40G;"AB24)%F,"1C@F;5+1E;4FH06%#E=41FH+=D("1(8-:0E#4C(/E=+?F%G'=G)%B<376(-+2
@r1197
GCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTC
+
-.<5;2&)C7<>-BH5;;GCHA?"B7<B9,B,"&G;@:"1$>,F;:#:66H<A,.EH45F%(<+DB)5:?+>BD)==7HH;C;55='!<6DB"9<DB4?D)'H1FG*1C6-74A1F-><0<%65:35(57-%=-&7<94,B1H/(:?&+"#>"65'A%-+;H/<?*%A4H/
@r1198
TCTACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGNCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAA
+
4-=6:+.D=E-0A&5%2H>$!*C,&,<D<@0H(2,"F2(>;D'@@9#!B@'"9<H/>6616"C!=(<'%=G5E7B7>9F=*E>=A%EG0C;3G#-:"<;?&&)7"%5*511>CD28:/?#B@?6*7<3E&:8%GH$'=37.6>#'3D/?'1A(.0$7#G<'*=,1.52!*@DB"%)#.F,)1&.@#97D7>)!(/B/D((;,@B7-2
@r1199
CAGAGCGTGGAAACGTTAATCACTGGATGCTTAATGGCGGTNGCTGGTTCTTTAATCTCGATTACGACAAAGA
+
F0#5+-B68?<59>C<8&*<155;;5)89+4G/*/4&79;1>:A2E9/E@GB&"1CD/AA/#1850+(20H&"
@r1200
GATCTGCGCGTTCACGTCCGNCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTNTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGAGCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAA
+
:1)7;@6B;*.607<EA95$8B7519*1D#F1A!<)'()#&!@-23".#?HG?A--,>+9E/8%3/@-$C/(&:.D-%2%B;)D%D-!*?*9906.F2'GE(*GFB%342'%2F3HC/BE&BH=&:)3&05)%-**(49:#7$$+!7#8($A'.4201=3=F29A1*1,?@-,;6#=7,(G3)41)6>?.0'F?&D0&270,F>'!C+.H9187H(C=1,A7//'>8C<!#B(&/?:6!=?-<(84>4!,*@+-*9-A10-154C$;8'23-:<E>8!A&!>9*E%6%7'&5),/$+8B68/194:3/):+019%
@r1201
GATCCCCATTAAAGGGGCATNCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATNTTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAA
+
C4&.E7/!2+<1/440E*-"$"&B+;8F9BHD10!H6!9>#<4E='D"5A<&$571H.F3(@B1+#D;.$B>C"*)HF2,&B5<#;8)#>30*D<5*;4D(1<&,"$.&>1$*BE!CE*E$)#,>63'%!D=:0+="$(H)0?3H&#B34491/!D&)5*/D(;H&B6G>'<>F%(!05093)G#1&3.#<?0C<=&4<#9A0D07$.0+4BH3&8)F(%:FH<F"0@4B>F-)0+4D-6;=/@)'
@r1202
GACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCTAATTAACCCATCGTTGAGTCAAATTTACCCAATNTTATTCACCACTGAAAGCACAGCGGCTGGNTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCNGTTGAG
+
$+%#%(&%%+()%'##*!(&$'"%"(+!*!+'#!#%+)'*#'%&"&+))#%)+("""&$$*$+!'!"+%$!)"!'"$"%##+!"!+)&+'%*#!!*$%%%()++"+*)*+%*&))"+)!('$*))&!#(**"$%#%()')+#+&*(&&'&)"$)%%(('"#)+&*#'!)*!!!"!'+&%$("((#!"'("'
@r1203
CAGAGAAGAAACGACGNCGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGNCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGA
+
.#269C2F,/$F.42E.06+".H?=!A'!D!CD&&F52AB36$.D'+,5.:B=1*"$1AE$A*#F#,+C8HAAD';;D.9553$D)83F=*!0>24,#@@%8<B5:!&H2;;"E2#$7F"EF:$.)7E>(..8D50H3-)-E@E3B@F7(,30,/!9:548
@r1204
CAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTT
+
;4%)2+>H;&C/6&DB"5&!>?D)H$*6F4D72.9"47D%$HHH>13:
@r1205
TTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCT
+
5G=(EG1)B</-F/D?>;5=2"8.+F5+>?D5%EE;5+;7'+6@>1,-3D8(;"5-'!34@
@r1206
TTAGGAGGAGTNAAAGGATCAAATGCACTAAACGNAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGACAA
+
:0('D"F--@(>9+-??4'$D$/D;6'</(+D@?%7D)9/6(//9"",3H&'E@=0!9F:3&)+FC?%%$G1G?5&1;*:F/-G5
@r1207
AAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGNCAAGGC
+
661!"A@0,/<GHDC3H3&;%:)C01+E)H=0:F,,3=E.:!9A#-$/4<D*0HH8=C=4H:2/#;#@#4<@6E#-1.4:*(6.1FC4!'B:3F-(.);05864*%F)78D'!='/9=<,
@r1208
CCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGT
+
:*1CG&@C:.4.DE=&F769!21*(*:>+3E0?9':03;"95@%.F'';B2=(*.G>3
@r1209
GATTCTGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAAC
+
8EF&#D)-?E#7344B)9;+B)(,H"&7<#2192C7&7C:/!.@(>A(&1:88)9=$0..A)C:#3,=
@r1210
CGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACACCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGAC
+
:+!++@99/,#18,:75;1<"(9A+$E!30&/G))&2?(E#:;<B+"19G/#.#B;E>C693B(A"?,*6#/E"H'%B(,<3;@!A.;)%6G/C088)(=D?BFH?E!?C::%"8B@+H,.#74<":F"6>3&83F"F/,E@FD<6B..!G
@r1211
AACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATC
+
=F9+<,-'2&:,):/<%"B<*#97B!?'%:=0F,6FH1F4<"C1D22#'E2?FB6,2H?H%D95#F?&%C0D5>8@8*54H"/1$,;BB1"0*+&G1'-%""8&D0'
@r1212
NCCNTCAGTCANGCGAGCCAGGTGTTNCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGNGCTTCAGTTTNCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATA
+
!!""!%#)((%%)'*)++%!!(#!&%$#*+%()'))*%%*"*$"&!"!+)&%*($(!)))!"%+$%&*&++%&#$)%&*'%"$+#(!"'!(%+%&&#(*"(!"$'$)"$(+("&$(()$$%#!(+$"!(&+$'+%
@r1213
TCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACATCGATATGCAGCTCCGCCTGCCAGGTTTCGCTGTCCAGCTCTTCGCCCG
+
)+E6E/FG)AC39F8(HH!#%DG&3(5A###GH*@B==!."FF58>GAB:.9(9"5F@D.2"+F$!'+D'*'E399);G-H%3'3$)<-1+H,%..0A'#<+0<%.HA36;%0-!3336/79&66;=
@r1214
AACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGCTGTTCTTTAGGAGGAGTAAAAGGATCAAAT
+
&C19'E#HB)*01"'D+.6EE1)98A2/+)&C!'5$)#):.%DB)';+&F?91=E%AA$/<#'(7!(F0/5#A%->,1)D/B$<(:;,#<0<%B4
@r1215
GTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCAT
+
)<ECH.?D:%!70'&7!*!F,$@-G0C,G58H$35A>"1>=E14HH0@3#$!H2
@r1216
CCATATCGAGCAGAATGCCGTCCACCATNGGATCGCTGGCAG
+
686,AD>#9:E#"81>?60<E%C1%'#"35D=C!2+A)#=CB
@r1217
GCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCA
+
.4A)%?0008H;5*6)1;,E=?2F%&!=8*BG8!;./%H1+E+)5@D0<:/'H.'@34%C39
@r1218
TATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATAT
+
;6:9"'*548H'?F805=7(@3?(H6D1>0#G29#5&<63,G$682)+;3@:G??6.')6C'-3$5D4*#2>/<07DB-G.+D3C&&=E*B:AH&?B.#E)*9(0=E?!)74%1GD!;4/2F<B!@$0D5<1
@r1219
GCGTGAGTATNACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCT
+
E,)D4D64(?C"537<33D)3.41)=".?8!B&;F"2&E43323;/@35FAF/-'B8#-"D)(2@.3/E*%2#<A.;:,G40!A,$E3=#@G&
@r1220
TGCAGTTCTGTACCGGTTNTNCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGG
+
0.E&'E;#$;"D0F$&"A72!6"5%2,-:C>3EA3+*,863.5C'7#?03H9@:0!9E<4A4;:#).:-H<%ED+:#05E*3&*;8,E$&!643;C"
@r1221
CAATATCCAGCACCACATCCCAAATGGATTTGAATGCCNGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATNTTCTCTTTCAGG
+
=A3:'A13%5$2%0.#FD&+9H..',$='%%AG9:93$.!*F!!(C:;1,##)061>#3F*B*6!B7EC3/7B"9F;?%))<1<3%H6?
@r1222
NGCNNCCGCTGNNNNCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCANCGA
+
#&%!%'&'&%("##!)+$+((!"+(%'&"#*!*$*'*'$!!)')'($+$('**(+**'
@r1223
GATGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGNAGGAATAAGAATTACCGATNTCGATACATCAGGAATATTTGATTCAGATGA
+
")(+&&"+("!$"!'!"%&')&**"(!!%)"$%(&&+)#!!*$&''*#"'('"'&'$+*"*(*$!*)*&$)*")#%*"+'%'!)+*$$)'((&%('('%*'#!!%)%&!!'(%+))***&+%*"')*#)*((&'!#&"*%+!(*($*'!&+"&#)+#()$'&&!#+&(""%"%"
@r1224
GCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACAACGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTTCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATAATCCCCCTGTTCGACAGCTCTCACATCG
+
*8;1$(E@D4&--;43245;GGACDG?G>$G&2F-6A:?0>(3ACHA30E+%##BF:5'%BC6G=?>.&>B<@2;E/6AD4EC0=;4'49EFBH)-?#31304<<05:0$1=+B48/.?%&>#,($+-636+;35/:6B(.131)ED6AA8)",:)//C104;398BAH(F-.)1-$'<=#A#-@D$<<'1A#;#<5:;5614D3268=5E"(F3*:E*C>@=@F,6#
@r1225
AGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAG
+
7G.<>!9(?C@!=65C793/EH>D$E>65:#8EAG++=<G14*!=2>&<;<G27C-=(#'99><=/&)*7&'31917%5(>)4B&'!C
@r1226
TAATGAATTATCAAAGGTTTAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATNAGATGCGTGT
+
<&70:<C@!!C0$>28&;/4DGH.5?(9@<*6EH'>9:>319,*&G/A'@)E8F61@9A=%?.2-C)*#%*.,'3+%?!D)A-&7&?:C,%C<7;6*>.B)*H%5''B;4<8:<7+*,CBD:<F&H7"786;%@E5#>D0";#G:'@C'-2/>B7
@r1227
TTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTNCGCAAACATCTGGCGGGTTGC
+
#D6%D()<!@'<F++%?E=%;2+&>+>4?-?)203&1F&:)?D&,G>E@C;<%.GG>E:==51;44")B=&905:+H/&F;0?EEH046
@r1228
TCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAANATAGTGAATTAGTTACACAGGAAATTTTTAATA
+
EH?+&CD2<:&38@':78&:4>20>*C"(6)47-?F$36E!D!-#?&0*&4C5+3<7,E2#8DC>GBG:6(;B4+@=((&2C,-7
@r1229
TATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCG
+
$+#$)!*)+'+$##"+)#&(&"+#'&#&&+%*&&+%')*&*'(!&+!"+%(%"$#!'++#'!#*#&(")"&&)'!'%%%#)"$#+(%&))%#&"%"$$*'*"*)#(+*(()+"%'(##""%))
@r1230
ANCCAATGGACAGAATCACCGATTCTCAACTCAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAG
+
51":C@).9(H9##>2;41:--+'B#HH;0"8'/$6:C%1@B3929$/=(2+&@6'+%.1#"@F-8:'<9EF+G/6*:E)>
@r1231
AGGGGTACACGAGAACCACCGAGCCTGNTGTGGTTAAAAGACAGGCAC
+
>(!7D$#;3F<@%08$<H&EG,1A=B'?.9:FB"?$?C<52/D??)'%
@r1232
NTCCANTGTNCGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGANTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAAC
+
"&#"*!'*(&#+%)$!$"$(%%&')%%**$!!%+"'!&!+%(&("!!"$+"()%%')(!&+#!!*+#$#&%+%(**&')+++%""&+$%$+)''"(+%#""##(%&&$#()!)%
@r1233
CGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCANATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTNTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCTAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCNTTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCANTCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACNTTCTCTGCACCACGATCAACCAAATCGC
+
3F6A)A#?;!3=2))@77)?>33))$F,!>;$79AED*,68B"4B)%>4=%.BC;3)?(?/>H!<*B<,F<4F)B3>=47*F0AF*9-?*H@-0@#2"<H5&G1%6*3)/:;6?G1+A<D!$G,(#E.1);F*>:$<)*3&;!H:./:!=CGG"25';>02)"'<!E*?69CF4?G)C3,,!#A#H2<:64"@3@/:G9>%"83!83*6<>D;?/"5G;0);3!G$;H@+>":E67(9?565C4+C@>/"<3'B''<6*0)$5#1@+93/)#/&>2@EC..#==3B+45:'FG+@1%7((-+,68.CG:CBD*>GG/6';23::C0!=$6&1G%&0D*$HF>9(3'7'</D9)0ED6454;E)3'.D2;"EA*(
@r1234
GTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCG
+
9$3?H9H=6@=@+1.9#C'6;!B-3)7$43",E%)091%27.-5,&0;,4(,D&HF1D
@r1235
GCACAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTTCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATT
+
2-%)?B!<"7=B('.&-(>2<#H(@&&!/+0(-&F+5=$/E?-/"--B+'6?-DC>2)!>),=*%?)>28=(=./*7C/F<D>9$>0121745F".-&=/&6(4H@3@!A>67:E@A*<%;"6D$(5%"BG%$DA24%=7?CD,;$%*AA6;6567'?',:=+3,C69#.41C;%>=(@>:620?5H=7:AAB+/%#=
@r1236
GCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTCGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGC
+
E3,?FBG%$4(8*3<?;'C$%>')64=@06)33B;>;;9E6%2<?::-(5*DD.*B*D)6D17HA)18));/-!E9.,B1D+0(!1:E&:"B01#?(DD-%92B,88'5(()3<8F5*#4/(-;.D;"?-BA17';5
@r1237
TCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAAC
+
0<G2409H*G.,FH)1(>*-C3.E3A*7$E"/@G/4H'4@.&H@C*G-":;0":+@.$1#!%2F,&
@r1238
AGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTT
+
EA83FE9-A/#=5D&>B/?D(.DB=#0@7CB)3G&/)@B1$(B;1.,:**-6=9D6"B/?E?C.802
@r1239
NNANAAAANGNANTNNNAATNTANNTAANCNANTAGNAAANNTATNNTTNTGTNGATNNNNNNGCNCAANNAGGNNATAANTNGNTNCNNNNNGNGNCNNNCGAAACNNNANNNANTGTNCNGATAGGTNTNAAGNNGGCCNTNACANNCAAAANNNNNNCGCNGANCNGGAGTNGNCGAANANANCTCNNATNGNNCNNGCNGNNNTGNANGATNNNNGNATNAATNNGNTNNCGANCTCCCATNNTG
+
#!##!$!!"!!#""##"$"#!$#!"!"$$$"#!##!#$#!$#"$"!!$###!#!#""$$$#$###!$$"$"#!#!!###$$!$!###!#"#"##!$"$$#""""$!##$"$$$#"!####$##"!""#$!###"!#"!""!$!$#"!#$$$"$"!$"#!!$##!$$"$!$!!##""$"$#!#"$"!##!"$#"$$"!!#""!!$$#"$#""$!"!"#!$$!#!!$$!#"#!###$#$$$#!$!!!$!"!
@r1240
GANTNTGNCTCCCANNGNNTNTGAAAANGNTTNNGNAGNTCTNTANNNNTCTCCCNATGGNNT
+
#"!!$"!!!$#!"####$"$#$$"!$"#$#!#!$!#!!!#!#"#!#"!!"$"$#!$"#$!!!!
@r1241
TNCCNCATTGAAGTGCCCCATCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATNAACAAATATTAACA
+
*&'(!**"%')!)**%')$"+%!+)+($#!&+'#+')""'))%#*"%&#*))!*#"&#!$"!+"&#%$"'+%#&""&$+(%$%'!$%!"'$!+$)(*
@r1242
TCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGNTCATTCTTTACCGCCGGAGCCACCC
+
@$+&5H/>(B$D/B.<)?/)E*-((&>:""HA8'3?(+F>CC;?H&,<=$#=7**F./+*AA*$6HB"9@9),91E#0A:H=A.?+7
@r1243
GTTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCNCCACCATTGCC
+
5B'A.;G907F8!3(2&*BG8C*9-'$"1*2A5057%6@*(0D97%0DG7!?C%.-G.*(,$)@A:2)"->+#52<-4&-@%F4@@H?C"9<B94#!(2=9>?@.*0,?>#C7)F*="<0%
@r1244
ANTGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTT
+
*"(%:@-.CA;9>$%7)6*4!#%?@E+"%$$G:=+).4++8
@r1245
TGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAG
+
4;1(7$9E+91!H=3D<+*5,5C4*=D8.8%H>$#,8:@<713*,,+-&.5,$4.%/:B-G*?"B9E3()4?&+A)<CAA1@2"/($/F:*;(%-'68-+&A,'F08->3(!+D/9&%5C8B7H$.@+'7&
@r1246
ATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCANAGCTGCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGG
+
'23&HGEB1:/E?#'')##/G+??<@(/44F!&G!=B%();<@)F+<F(,F//672.;&=?835%%@2A-8E5C"%";4/3"CC1&;>C%$DF=>-ECD5/G'1F..*6
@r1247
TTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACAAGTAAGAAGATAGCAGT
+
2$-'A=(D+H=%$7-30=9DD/C,5AA*(;,>,9;!46)C:0=/'*E9H2>/+23B?)%/0)-.D;.&210<=>%1>G&=<%!G346,-7*F"EG8=?')%,3(29$&:G+H
@r1248
TTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACANGTCGGTTTTCC
+
H-!G6)=@$=FD!)/+@2)2!'-.D26C<2/8+8@/,536;83D!-.5.G3,-6B52#5."G<523B*$D"8.!>;#"H/7392>9:=BG&5.1&67=>2E2=91=%A+!213?2+BG
@r1249
CCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTC
+
%648<-?-*?5$.#.(19.3)D-),A.!'&(:,A9:6';9
@r1250
ACATTTCGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTNCCAGCCGTTGTTCGGGTC
+
=A&3#9E#*9A0>6+3*!537,.B2@!@#C6-27$"&>?"4*;F&4@2HD?))C+C@HH8-:'"7>?ED$&23C@,<
@r1251
NAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAAT
+
!4+=!(<$&2./%C,7DA,5"$?B7*8.#7$,6>%(&/!-+
@r1252
TGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGGACTGAGA
+
"FH!H+%GF->E?<!2"!B&--86-"?<;'H-!96$1H3+$D*
@r1253
CCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGANCCTGCAGACGGCTCAG
+
51+0@>0%0#3C,AE&1:1/0677:6)(B9-',A<H!987.;9>C9(":?HA%D?A44002.;?D&+E<$*?
@r1254
TGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAG
+
):'G+(5H:<F8#619/'80)/0!9:*$2+G!8EF%E83B:6:
@r1255
ATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCA
+
.::H*,@<F72!=%..C,A.)7)9F'1-1+8H0/+='".95>
@r1256
GATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCNTACCAATAACGCTTCACTCGAGGCGTTTTTCGNTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCC
+
%+3)E?64$1:)F/':-#54D9D19G,?EBG;+)2,5)@:!?#*><787<.:9/GG7972C21*.<@/'B(%=9G*))4$8+4<4A1@?G&E&%GAB'82A*9/94G!-'5H4<;C#0D.?/)('B<&CB997*&7.$3;:.(
@r1257
ACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGA
+
(3*<G*+;64D0@=EH0&3F9D-A4&'701+0@3F,9=-DE6)<()/7"2*,*3:@B$)8
@r1258
GTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGNANCAATGTTAGNTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAG
+
9"FE(C'@!8AFG&*9(DHH)HH>)!1!H4%>-)?H>)=(2;,5C?F6&)5+!/B&D)@CH#<!3;CE=?E%8+?)49/H;6)(5:%D(97/!*@CE8>#4(#(2G,"&$$10<0";8(:-;+-F$1C*!G"B8/55D)(@=0G8B7
@r1259
CGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGC
+
AC*72A&/1<#8&6+13G,7#H&+@ED:!B$1!CD(9.+4G0/8*%@G(%*9
@r1260
GACACCATCGATTCCAGTAGGGTTGATTGGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCGT
+
DG?''0AGE@F$79:36640@0!%7&C0.;CC28@C.DG#;'==53:9@:);>2G";>;9(+=,'H@+14<:5&"!E)"
@r1261
AACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGG
+
<&@"&?H79!9+(G<?!+<5DG-7)/3..>;8(B6>DE5+)C<".0B:A@35-85$A5?-"><?"88D3<!G;1B87@H7?*+=;!D?)5>68F+!*E!9(@(H;@CC-%60@/%=0
@r1262
CCCCCACGCATTTACNGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGAACAGNCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCC
+
55/@;<EH8*1(7<A=6/.?2,;32")&:-%>;!9"D9F&4/FG)#1&$A/(&,%&5E291),)A.*7!E<.27"C:.:GA?>,>8=$9@8>-?3:6;>.BB/$C615G3&C,,+&513#<!#@$6F&4&<'&?8)(&<00H89%%-$41;+:,8;4"A6=C9H$7)G8F<AF9/8>H182$F"
@r1263
CTTCNTTGNCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGA
+
<5=G@$>>H0."D('$/9<+0<?%#F&*!6.G@D$=&=D3'G<,#;?"8:0*1+
@r1264
AAAANGAAANNAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGNATTAAATGCTTATAACGCCNCATTGCTTGCAAAAATTCTCAAAGNTAGCNTTGAAGAATTTAGCCCTTCAATCNCCAGAGAAATCTAAGAC
+
**'$#!$)&$!%+#)'*&&$**)&&*&'%$%)#(+*%$!%"'"")*%#)"$!%+%+'+#&$!%+('#)#)(('(%)#!+!)&)+&(%$"'#%&&!##+*''#'(&&""#'$&++'#"%$'&+%+'$$"%"$#+##'$*'*!"!+!"''*%!*+'$#"$'&"($#&#!*%'(*+#"'$(!&())")&$
@r1265
GNNCTATNANNCNNNNNNGCGGNAANACNGCGGTATCTGGGACGGAACGNTTAAACCGGCATACAGCAACNACATGGCCTGGTGTCTGTNGGATATGCTGACCCATCCGCGC
+
(*!&"#(*&"(%(")"%$"$')!&'+%((+"($)'!&****&)!('))$+)*#+*$!$#&%%*$&#)%!#+$()(*&*(&+*$"#")()'&+(#!)%)"*)&"'#%%!!!"%
@r1266
TCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATNCGGAAACTGCTGTCT
+
7)9&22H%;:=E+43;"HF!%G5.:,;*3G"-+2"5.3%-0@5F.@@;,.E6!9)8/6H)6'>3H
@r1267
CGAGGGATAAAACATCCCTCAAATTGGGNGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTA
+
@2'G8'E5F93010,.5%&>'=3=DC?2<:,B+%59/,-B3G?"5D@5+%?H96A/447GAD)'@),AGC/H
@r1268
TTTTTCCGTCACCCAGCCACCGTTACGTTGNATCTGAACCAGCAGGCGGACTTCCGACG
+
H30-(*+D@0?G>>E;5A:#*'H=0?C"43'2"/36.#>B0D*/F:F3/29,"@>4H!&
@r1269
AGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCC
+
D/,2)1"53''A/&%9)3$<G3E@#B*5&2'/-4D2=*3A:!96"&>3(AA1)9:,@/%"E>$7/D&A;>G26CD8
@r1270
CGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACGCGCGTATCGTTTCATCGGCNCGGGCAATGGCAGCATCGAACAGGTTNTCGAAAT
+
:'??%4F@$'2!32*4-72A:$C""H#F=90D&<6:/:)@?(B;5!3<7@B5.*"E;A$#1;(C#B"6$/8;(8=-$0/"(@;)@,(B$6,/A!693)(0=)>9&$$5%>:8#)"%:0*HG:1"9DD08A&(G@)%FD#?>))B31?A>DB22<G"<H8/76DB7?#7/<47$.;=02;!:2-D#;,)B'#!7&.9B3&0+@83.!.B=<@
@r1271
AGNCACACCGGTGCAAANCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTNCCGGAGCGGGGTTTT
+
-)EH#@(8#?6'G28?)342*F053&%+G.DG*+;C<=!H?F3!7:;,D-5E7=(&73E36")>)5(>8@3;##6B-6%")(H%D
@r1272
AGNTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAANGGACG
+
:"@%'!0&E"1C$@,8:'A@(>-E+!G88)7;#7D-.9<>$$*3:-6
@r1273
CCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGT
+
&/+G>#9/C";))6.5'G41(B"!/A%-&1G?>)%/@&1;;D0&4*?%$8='4?GB96B.?
@r1274
GCGATCACCGTCANGCGTGATGCACTGGATGCACGTAAATCCCG
+
351?22D/("2*2-3$."),B09D5>,06+*!.:#4!%F5"5=@
@r1275
CCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCAT
+
>?!;E:E93)?7C%A67:H%84(GF1%="66'*%,AD-F-?%A&4*1(>DFAE17%.2/*@/-=>9=
@r1276
ACCNGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTC
+
81%5@+E@%3&9-35/B-.3;!,)).>2%79?+'6A)6E-.,'F)B-8-1#3D.AB#:7"2E0!H,;-H&?!H-B#'6H;!3=+:.3
@r1277
GTCCAGAGCTCATTCGAAGCAGATATTTCTGGATAATGTCATAAAACAATTTAGTGAATNTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCT
+
80/F5+3BB.1H;>$H1F5B9G:%BGA364?.C5&&1G2//,:8B25/&=/.3%0%$3AB.H5%9,.1".@&>1+6BG:#6;'.%)"9.:GE9"H6">(C:G<"
@r1278
GACTGCGTATCCAGCTCACTCTCAATNGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGC
+
%,,@?!=?>=FE8$76*DF6C?*@83$2FF>:!.6,$<+B2%(HD**:!B1F$5/>/%-'8<F
@r1279
GATATAGATGATTAAACCCAATATTACATAACAATCCTCGCAC
+
##0*:-!,&:@2)GG*7)3*A/F2,C$B3F53.HA4E$-5D:H
@r1280
NGTGAACGATGCGTAATGTGTGTATNGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCNTGCGGAAGGT
+
!%(#+')#)#''#&*((&$*&"&(%)&(*)%"*"#+#&!"'**!#%*''#'*##)'$$"$!$#%!!**((((+&())"'+#
@r1281
TNTNGNAAGAATTTCTTNGTCGCAATCGAGATTAAAGAACCAGCCACCGCCATTANGCAGCCAGTGATTAACGTTTCCACGCTNTGATAAGCCATCAATC
+
()#(*$"((%'&#*$""$#('""&"'+!("#&&+#)+%$"$%+)#+!$*&""!*(%$%$%&+&&!'*)(''"&'+('(##+*#$**#%'#'(&+!$(+'!
@r1282
NNTATCTCGNCTNAATCACCAACTCGTTGCCCGGTAACTGTNGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTNTC
+
!%(%&&&)&!#('%+()%#%""!*+)%!)"#%&$"%"(!!$%*(%#%+!"+!)!*!')##"(()')+)&%'"&##&(
@r1283
NAANCTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATNCCCC
+
*)6,G>,!A#$0-55?-:+.<A84'F6'75-79%(1801%"5>'4A(%.B,#=0+$<>,>
@r1284
CTNNAATGNTCNTCNNTNCNNGNNNNTTCTGNCGNTNGNNTCGANCNNCTNNTCACAGANNGNGCNATNCCAGGNGTNNNGGANCN
+
##$!##$""$$"#""##!""$$$!"!$#$#$!###""!$$"#""!"!"!"##"$!##$##!!#$##"$"#!!$"$!!$!!##$"!#
@r1285
GCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGCCCAGCNTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTA
+
+'A%7FEB=3)((G'?,<,?CH;(3E=82"H$(,&0H3:C;?DC3BB6+C%3)7@4!)>&"D.<=)7A+"3"6%,F(,9;4(91>-:$G<A4".F<+(HA%>CE"**9+?5.:5=-CD:&6%%B:"-G'H9:%9DB-D:.'F88!5+0A$'&0,.9F
@r1286
CTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGTTCAGTGCGTCCTGCTGATGTGATCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCA
+
9@@4+!:"/8&*"1":F8)=-88/<=-!>?(11>;1+)E#E+?!9&40@:?=,23*'*<F9:6%+$";GEB0#=F&!/-1$1%A?6!)+%(*(@,,<@F#5
@r1287
CTCATCATCAATGAAAATCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGC
+
GC,D"BD#$12BCB/:%!&<(42#/'*"3(,7/;)"?&!7$@',?!&@)BF2(;)6=,@8G5,)6.*,."=E%0?F*??.5
@r1288
CTCTCACCTACCAAACAATGNCCCCCTGCAAAAAATAAATTCATATANAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACNGAG
+
A$>!ED64'?@9!!2BDB!HD!G8D58?B3*!491.=$F/!*0H'G2.41)+%"5%+)<:H89*0&/)?E$+19<#:DGA>'=2'6G&78&>F;0F5EC2;<&FD5G*?*>G.#='(>,G06</GC/
@r1289
CAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCTGTTTGTTCATCAGGATCGTG
+
3&7""6A653DF#$'#;"E4/BG.&???!A74?E,"C5!$)FE0E*-$@?AE%;/+AE9@%$B,+(B-<B%;C&%%/<2*
@r1290
TCTTTCAGAAATTCATGGACAGTTCTCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGCTTAATTCTATG
+
?2>-@C@)!>;*#&&4:C+#AA,CC@<:-'6;+D%51!C?.7.4479EDEE"F/8%+D"GE;)0)8B:;?="%*+B8<!.?@(%#"A+#F*$:H7=<HAF):D$>@HF/>1H0A#,H9:87ED*<@E"+##5!,""$6/'>*
@r1291
TGCGAATGCCANCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCT
+
8-%&$*H$55>>/:34=!,G-/1'F2@0,)@2=&>81?"@B%7'-9=,9G0/G7E49GG/47
@r1292
ATCNGGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGNGATGGCAATTTTTACGCCTGTTTTGCTTTGCTC
+
(%)"+&!#&''$%'%#")&+%!*#'#"#('+'+*)##*"('#$#"%+$'($&+&*+*"))%+'"+(*%##'$#)"!")*(#&)$&*$
@r1293
NANNNATTCCTGANGNCTNNATATCNGTNNTTCTTCTTNCTTCGANACCNTNCGNTNGAGGCCATCCTTCCNGACCATTTCCANCATTCCAGTCGAACTCACACA
+
!&"#!&&&"!()$!(!%*##'&&&"!**&!%%''*%$%"!"*)%*%'*'$%!#*!)#$)")$+++&!*++#"*!'"#("%&++'#+'&"$(&")(%*"$('"!(!
@r1294
GTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTT
+
3;!;(;C9B'7)!CD)@()F:)9F,'">#+G.BD%9.$:*,$
@r1295
TGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGNTTATTGAGCGCTTATCTTTCC
+
'?2$6C.?=H'#=HEB%)<">#-5(H.;1D.)*BD@6<*F4&+%+F*!0(7B8!33=?H=D/+A!@G0'*
@r1296
GAAGAACAAGCAGANAAANATATTTTTTGGCGTTATACAGCTGACAGA
+
:/DD3775?A7!0F+!-359!A379.05(5EG,2#?BA!D(3?HB@<*
@r1297
CTATGGCTTCATTNGGATATCAGAGCTATGGCTCAGAAAAGCAAGCA
+
?;!(>25B2(E!.2+E#G/"C,!&1G'?+CB%<)2)->@AG8;$4F(
@r1298
GTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCC
+
&&,)2;.1):!'!8,31E82DA;4<-(F25=A:9G/*)+7:&3'+@7*;G?;,75'D2$44H*>!;;CH#@D5-=H16$+BB)
@r1299
CAGAGACACCTTATGTTCTATACATNCAATTACAACATCAGGGTAACTCATAGAAA
+
'<;??*:B>-F-)(%(>,/1,3@>E:AGC:2D.?.H%"&H*2E5E:D(+H&43&1@
@r1300
TTGAGCTCGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTGCCTATTGAGGATATTTACTGGACTGAAGTAGTTGCCAGCTATGATCCATATAATATTGAGAAAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCT
+
1C95'"!5%9.!82F<CG4#8<.,A5,8)1B.&65:47:@::D!?0C$409?4C:(BE4<6).G#9$,=>+422H,)3!?*=2')/-'B%%'F$G6<775*/C%1;;##/H2/>%C%030:&B#CA4>!3,326G'-<A@#/!)<'+C8CAE/6C8E31#:4HF(G)'G%."
@r1301
GTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGCTAATTCTTATTCCTTCGNTACCATC
+
'**7#8)/B%40"2<E2E"7&4<9&27F56E?)2<(<.*)?&8!B@@:=,=8%-B::E).0-3*:15??.3/,.C3>?&99!D$C#5=@06.610H
@r1302
TTTGGCTCNGANNNNTNNTNNATTAATNTANNATNNATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAG
+
)$#%'%*&$%#!"$%(""("#')*!)"&%'%"!$#""(&(*+&+'#!'#%'(&"#!*&$!+$(#)&)$(+&%&%%%
@r1303
ANTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTNTGACTCTGCNGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATT
+
*!4GD?/G.E;34.;8!H1@>@4E,:2)C7&"@*E,<<C%362=*)+5(=6+%93'2+8)/F>;'$"30-;7%2>F2")B-.BG5:#3?F%3949@.;24-1FED5F='$.?/9>@/91@5C<")0F#F5F#8-)G/C6$!9F50H(18BG"@A+)93$=.H=:8!%;4";C(1(!A!)!0@#49D%%!5$++7?2?$!)2%G,5B<-/)/$-#=,C.=).A%,/<*E1%"G9C3B6G*01@%(GE")1G?G67#@)!)E%H#0&AF4$/"=>:E/'
@r1304
GGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAAC
+
-=/G+"+=6.F<:B4G82>7BHG,C==*59+7B120(42.>/
@r1305
GTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAANACGAATGAG
+
.G<$1%H,5&#BEGD:!/!G2@H.6>&@6<4;@.7F':B=!%4'#?7G%F$-;E-0:;60,@#70
@r1306
CACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAG
+
E7%>.?6AC4$$/"FH.!128G#,H=F-!F@>2("340>!%G'CD14F<
@r1307
GGGTAACTCACGGGGTATCCATGTCCATTTCTGTGGCATCCAGCCAGGANACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGG
+
,??$<08A,F+%F;&DA3/'&8'.8#>'9@6)<-A0C-9.98;*5+8!28,1,.023-.)DE/&*.F-,!*E7>C*&;9038%@68F'D32$"3'&/2(4E1C6-3B$DA;646:5HG-)C6H.
@r1308
GGACANCNATNTCNGCACTNGTCNTCGCGATAGGTCCAGGTG
+
&(#*!!*$"'"(#$%&'(%%('&$&(+%)()('(+"*$&!)'
@r1309
NCNANGCTCATTGACGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGNACATCCCNCGTTCTTC
+
'*##%($+#)$$"'##'$)*#'($%++%#)(&%&#'&))(&!#+$%'"#$"+%)+!)#*)+&'!*&*%'''*"##*#()$$(&*#$#'#+$%*!'""
@r1310
ATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGC
+
2$H),D'='9..8*9+7,"&#<2,6EE+71D;"!G%!C8%1):785.:A2G$?:2#-!?+;6"6&0)CDHC%%&5'-H;'G6C18$)@5<!$@=H
@r1311
AGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTNTT
+
<3CED>5!GH1:&&-FF%%+!!%+1=//->5;;+'%D"9,A=1D$0&".A%"/*<$2A<+$H9+8#=B'1<0DC((AG-DF=3(C
@r1312
AGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCNACCTGACAAACACAGACTGGATTTACGGGGTGGATCTTTGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAAC
+
BD>D)AGB2H<A#?-3176%(+>4<.>)?2,E/#<A&'%@@E6=7-45%("*-.(1F364##F/'!)<,8@B)"CC."/$0C@H&96&7")H<@B*38#/'776)E*G"/,3,&0;/74B+G1-,"@3A&-'>1*<$";75->-<$><=(9:))3F%%*<(DG36$-8B)6!&6"&7',H26=<F<+$4:-4.E3GE=H)?7B*1'H?H/.#,#!9);:)GF".B'-B6#+H-A(,#@36>*:0G9>==A=$*A8+&E3/+B49#'5A41HA?$)1'"038(%669HG89G2*""+60'/;2H@'+2B&..?;9%8@29D7D,@'B6$1=?3.51F!0-8;:,5=G48-;+?+G#EH?"G;?<?<9?9D?#$=2"!1"300A"B?1-
@r1313
ACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATG
+
'/GC.'8#&:>5.@<5CED?#:467596#"!0?E;:;#A%!5#BCG$BB))
@r1314
TGAAACGACAGAGGCCAAAAAGCCTCGCTTNCAGCACCTGTCNTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTNAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGATG
+
)(F#8FE3,+7!70C<,(/H9(9C7"8!!--<8"&:(+/C9.H)84&$7)#H9$)/"3$&5'=9F9-"9G8"GA.G#<?,H:07>73/D$/&G%!7D5.#%9C%69+E)96;28C:!6+(*/+.D!@G"+.F@=&F#+=*4+GF=/$)?E!9/0!=;A$%>@2A7)))40B==B)>H6%.42E+!/HE)A3<"!.A0E1$2F.G()D/@B85H!:7:$&<*
@r1315
CGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCNGGCAGGCGACGCAGGGTNATCTGCGGATTCACTTCATGCTT
+
3H;C?B3?69;?"=FAC(53B84;E;D+%4'6H-A&C2%CDB"2B4'=*0))-/BH=,E-%**,HG2EA2HB061?+%>-6)@
@r1316
NNNTTANGNGACTNNGCNCAGCAAAAATAAAGGGAAAGAT
+
&)!'(*&#"'%(*)!#%&+$+))&(%('+(')"'$!"&*(
@r1317
GCCATTACGGGTCCAGATCCCGGTGTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGANGACACAGCCATTATGCTCGCAGAGATAAAAC
+
1>6!#0;*B6"%&E4;H)%)C.5:F,+4;%A6%F-8!,(0*&:23$;,.<&35F2.!E?B'6!5%E$6$0,&E:%'2)<@6G8%$G,GGF@&9..3?%89#(/4@A
@r1318
AATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCNGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTA
+
&5G;@<=?CH/<@#(9G?,B;%A17$C<!6*>&9;*@+="H*E+//!6*?*D+8C)5A@-"8E9."A@=<3C/5DA)>=9.C>H!-"@3$G8>E858(379'(:E>&6?'
@r1319
GGCTGTTCCGGGTGATCNCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACNGAAA
+
8=78)"0+&$0C<(?(0#@2B<:-=C3'$&6)@D/H:+!"FE:-E&!,!2*5-F?-*>#7H7-0-F9+@8/'B(48="#)%$D!$@7AD%??+7/F7C&4).
@r1320
NAAATTTTCATAAATAGCGAAAACCNGCGAGGTCGCCGCCCGTCACTGC
+
#"$+"$$+&%"'$&')!%!)$%"(&)"!)'))'!*!"!&&%(&&$$!$)
@r1321
CAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAATAA
+
=&.>)(*$8:-#,#CE)3(:+=$&%6%#89GF*-FCEC1C""&5(<"<6>F%A!36H$E%!5:2G+2*>%D1)DHA%8/<D
@r1322
AATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCAC
+
G!:"D/A??'>H94H4E;-.5C5"A72>.@65;3'D;,?"F6%DE6'<&)"7C!*1.2;7)!=H")ECCF
@r1323
TATTTCCTTAGATAACAATTGATTGAATGTATGCAAATGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGA
+
94311#1)'(9F?58$;!<+2(8'*HD#>?A<(#8@911349(7;*3,,-,<%50@CH7.8D;7G//0-9A?#+?.!#943'5$@9=$3@63>
@r1324
AAGTGGTATGATATCNTAGATGGATATCTATATNTCGCGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCT
+
+4FH#D(#/D2%<:";8!'?@*8;5'88FFB%/1(8:4$!<1#<""7F909=2$>.,-#,29CBE%.13#:!9#G&=;$68&>F,C+:85/<-
@r1325
NCGNCNTAAGANGNAAANCNNTGCCGGGTANATGAAAGAG
+
"%!#'$&"(%*$#!)%&$*##'(&$)'#'*!+!$!&""++
@r1326
TCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGA
+
G>8%.,?'()=5(:;=03B9E&6<1EF*+14D*55/5-&238:&AH.,/9>?,<C)<+"H*EE;9E7GBC42BCD5.FG,>9>D8?8@>+/!2D:.,HF<7H;4HF//-*?G'$H),
@r1327
CTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGNA
+
'H5(A01"*9(.5<#'8G(2A!71#.)5<3'50+/D33-DE65A4E0*C.@=6E!20"0!3@,H$A9<;3B(HG%4-
@r1328
AACGNAANNCCAGGAAAGCTGCTGATACGAGACACCCAGCCCGGNAGCGATATACCGCA
+
'"'#$''))'##"'$$"((')*"(%$++!"'+(&#$$%%'&&&$!+*(&#&)"!+!&)+
@r1329
TTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAAGAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGNTTAGCAATACGCTTACTCCCAT
+
,9-05E64#)4<$5?%6B&+<#@(*#/-<%B5CB!;*-C>HD;7"#8?11"#<24A3%!+!;<&@""0BF5(-"%?F37<G'6+8F0:4F=1!B,C26+&($58'6,#"@+@),43<3)<10&"2&,G;<0,C8(82:4D"2*-7AC0-&0:%G1.+7-@B:D*%'#E7D-C-/;C3#-F&F)%F<,B=H#:C&-A3,>)-7>55!*:'22BB9@<CA$D:%H%!!9?;87$/+,/)%6<9H1):(-:<H0D(>@9>.$+"!&C',
@r1330
ATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAG
+
9;8-D?.4/*#2D.>%+*E.#DG(?@C&33>5,*7</644#9C4(3$/$$;0&:F1=+807?9-3=#C<G*;,%#609HH;)>C"=A=E42E.>HHB)B9F(58-$6>4E0)(3!%$G2373.E6)F(-!)"<05AB*=HH#AA7:(*18-2#7BG(E+0G+3)E0@G0?C(.47/6'(3*2:0).G"EC9<!C>2:?CE#@F'5A9D:/-1@>&%E
@r1331
ACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGC
+
9*/=@FG4.B"$*=',49A?#",+@>4>A;57G+@0)(D2"H'(B9G/;/&&F=EAHG+/2H=3=$?8@H%3@4H#'-@E0E6B60+6#H"1
@r1332
CTGCTCTCCCGATGGTTTATGCAGTGACNGCAACGGCCTTGAACTGAAATGCCNGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGNCTTTCTGTTATCCGAAATTTCGGCGGTCAGGTGCTGCACCGCTGGCGGCGTGA
+
3*$=A.!BD"".+*@C6#);5C29DB:D/42F/>"3<!5FE@B=<%;<,!@#5"HD/7E7D,5-$B+-A<61$3$<G*E$)D1*D>@>2G@C>+C$1#(:4:E6;B'(C>*.A<3F$0?F0):D(C,8(0@:<(4"=E>=%FF./0-.G),;#AC<&EH-7'%0?H)=A+7:F,).8+9%CA-@9>=:%33&>!G6@,)45*!%+/!D#/=DE(=58HH*"DB)9G?.);CH8>909,:GE4DE9(G)B5%$%A4)H1@)*/D5/=&#7&E(F+E?:)(?C;$/))-G=46=4/<E20!6GD+*.C)8&22@>$=5<*%4%#.$6$26B)(161"3?7)(F*)<<C>346C67*0'776#-+$)6F%8D&?@.*30+62!?E@/97:BD2B>%>/F;2695&-4F1<HFHF7B<7&99-F:3*&#=6!B9/CA?(0"G5!5*H441+62.3=2<B4EH/!5DC,9G$@C(
@r1333
TTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTTAGGATATNAACANATGTCAAACATCAAAAAATACATCA
+
%A'10(B0C;:=3EFB"0,8$FC(9,7<821H?+7&8*H"EE.$>%,>&6=.$:':*2/3*.E#B<9>=##8H48A3?=:*C4#)21&"!AA9A$
@r1334
GCCGTCTTTCAGGACNCCTGAAATCTTTACTGCCATATTCACCCCACA
+
5<%6C&'4+/1#&14";$7%>;BBA2>&G(A>0+#1::C:0"1E65D*
@r1335
TGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTA
+
:"A,)0F-70/#?:1<$%.$9AD,;=,A":>C*8-C=;4(3="5><;$6E24,2C%)94-5$//!0<2HC0499:=DE/:H@
@r1336
GGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTAT
+
3F>&+%9(#6(#G&'%#H+4$;:59;9.)#CHD9(8,2?+4!G$/FEB$H5.&"*74$5(3"F9;(5'@('5(AH9;0A@-3,5D?.842C(7=#78;$C.&0*E(7D8?A=6$%<#A5!'#3C.#D=G198F+)3)71B?;B
@r1337
AAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCGTCCAATTGATTTAATCAATACAAC
+
@+F1(/:>"=!CE0,D#42=E'$,.>40,928F)8<=H?'**<65#6+F;C/6@/!/'$A$B0*+40"/)F48D
@r1338
AGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATG
+
H=924%--%;&,G*!HFD!C&(%F)44,+;:$F9$6:G1,(6'A:4)&G6%::4+:"C%@"9:-,
@r1339
GTGTGAACCAATACTGAAAGAATGGGCNTGAGCACCGATAACAACCGGATGCTGGTGCGCACCAANACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGG
+
6;F<4?E-D101@3*F0A$%("H:!!#*>*:@8B&!($"0**HE#%A8>?E5$+./5F7=E&==D?1+5,==;;G+CC-")G?+?9,0-#!4:G:@'"59%=4$FH;G>@
@r1340
ATTGGTATANAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTNCGAATTANTACATGCCTTAGCTA
+
2;1*2(C&34*3"&)3A0)'$$:D,2=B@:75*C16)GC$7.>;A=@0&,*>A"&B!9+06&;3%%=;C&&,3'>!A</EH3F-F>#EEF#0;/!.,.D%1>.*.4C!/-D,&<#;A9!,,4FA34<B95'578'4
@r1341
TAACGGGAGGCGCTGTGGTTGATTTCGATAACCTGTTCGATGCTGCC
+
)($@>.2F@@G!5$?+7:=3@+3B,@@6$FE5F45A9=12D2#<"CE
@r1342
TTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGNTTGCGTAACAAAGTGCGGTCCTGCTGGCATTNTGGAGGGAAATACAACCGNCAGATG
+
,="97#G&G2.9'+1HG$)<'8H7:7-7/B>57'A;CE#AD>5*4H3#%E.4HC=#9>.0*-#83:,4AH$0:"'3F0*&0E=H+&H3$%:<HH2C6>:+2;3:82F830?=1(62/5,/!B%E26DDE':D)G5A"B3#3>%/(
@r1343
GTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGTTGGGGGGACTGAANCTCCACGCTAACCNGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGA
+
FB=9A2%H2B&G,%FF-=E'7)B,)?$9/<2,0DG9:92<7#:(/+9:0C)$7H@"H<%=;+/().3>7,&+;;@?9?"3C1$A8G2945E-5F9F,.(8&(@0C'7@00<>2,$.<3!;H>.G*EG)5A7DH&.E1.@>2((GC)63'F(554.9(06'E:4"$%(3*.;%;!4E)C+#C#:G=.!+;".H/)(<2/=<%#"$07?2-:)9(2<BD>$C8-05?,9!/D<%8&;*
@r1344
GGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGA
+
-F!EH%%+@@"6F00H=$*/($*48E<(<,?='?&F:":->)"F#==9H17%#H!5,'
@r1345
GGCAGACGTGGCGGCTGATTGTTGTGACGCTGGAGCATTCGTTTCTGA
+
=)7><</*,;.?(+B5*;2$9689;$0G::+<H=2*@?31*8A,C.*H
@r1346
NTGACGGACAGTGTGGGTGTGATNGCTTCCCTGGGGTTCGCCGNGTCGAAAAAGAGCAGNACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGG
+
$:+(D!6DF7%9D76FED#+(3A6)-"-:9:->D<A-*:/$,;>7,!*!<:6@<>F%%9(H5*C.,"%=?!8C?!B337>$1*9?C*5D/G:F79C&%HE78'21B+>%(<&A)DA>1/225:3,>*DG45/"5;D<5C3.36>%68D6'%9H7@B;EA22-7444H3E>/E*6EC<@;
@r1347
TCAATCTCTCTNACCGTTCCGNCCGCTTCTTTGAATTTTGCAATCGGNCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGCCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTG
+
@2B/E+!578("63%5!1D;;B7:@5E-'"7>E8418!<!&".8).((";(33+*C##2!G@'6"!D9E.E@AA2&HG/588G#>;*!5+/?9=50F)-><HE9#2$46H/2@-.;);?AC(2!:C8<!B-B98F,6D1'(77+%?:<F5/>'G:-1B+)8/A70-%;"-;+@%40F+)!*1
@r1348
TGCACGCAATGGTGTAGCANTAATTGCAACTCATTCCCCAGTAGTANTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCG
+
F5/F<)((E(")(!639E@'7B!!E&+)B+H5,D",BFF-=HG#$<7A"A%,$&/4"G2)7&"915-2AE@27)77$D'>F)H**8F?(*B.:A,>(A=DA474)>3'D$/FD#B4('?D*;#A+4FH5F&@7A
@r1349
NCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAG
+
#02#?%>>*%?)-64&B&9/??=EC$+=*+9<(;0-#FC9D=?
@r1350
GAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCNGGATGC
+
#?C#0H:.5=;4:,7@$=3B-#H19+8EF)0,D+'E8!=2?4G'@&@6,3
@r1351
GTCCTGCCACCGGAGAAACTAACGACAATTATCATGCAGCCCTGTCTCCCCCTCTCGC
+
>""#>+3>?A</08.<2'HD"4-G;)41*$'C>A*84;'8F$!++%;(?$1#A32@F&
@r1352
CCCGGNCGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGATAGTCCGGGCGGTAAATNCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTNCGGATTGCCGCACCGGCCGCACCGTCGAGGATTGAGCTGACGCCGGGCTATT
+
$%+'%'+&'%!""%$%'+(#!+!$&"'#*(*$%&)('+)*"*&#&*"*$&+'$&*")!"))*$%((')$"+#%))#!#**+**&"+(%(##&)#$*!"")!)(*$*#"&"(%""('$"!'**$$"#%""#+(&'+&&*&(%(!)'#!&)'!+%)#!%!(%!'#%$)*!
@r1353
GCTATTTCGCAGGTCTTTGAGTTTCNGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTAT
+
C-A5'.@B6A+$?%9@@&C9%"<=6:3D!6/,)G32"D%4("@9*-/F&7E4)AC?;903'G7<2-A/:&C!2<HE@96A)4+
@r1354
CCAACCCAGATAACGATCATATACATGGTTCTCTNCAGAGGTTCATTACTGAACACTCGTCCGAGAANAACGAGTGGATCCATTTCTCTACTCATCAAACNGTAGGGGTTGTAATNGTTTATCCGATTTCTCGCAGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGNTGATATATGGAAGAAGACTTTGAATCGAAGAGCATCCT
+
5'GF1#->G8+.&+"G2-E:"E=A.3(DB3>3!43D,@-!.G;B),BH0F<."+%!A*;'&F69*+D>/'HE>HE!5,$8(<-(8-'+<!@@$5AG+$4:!?"5';2;D"'/C9,(H-C=')=%.%7&%:#0/0F(@6,'0G*/F="0!;C/G@%FEB4=,'+!;>#?H?FE0!G1<8&&2#@4$.8*>$H59G!83<$FCE0=53"??4?6E4;G)%5*(>;!D1&1%/8B9E=%"+=!H!G<0"#3)=2.9,
@r1355
GCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCNTTATCGCCTG
+
8>3<$(*A!?4-G9-23%1#6(7.>G$AA+!/D?<<0*#3%20915,0C+A,%")
@r1356
ANNGGANNNCGNCAGNCCNNANTNGNNCAAGGTCANAANTNNNCANNGANNANTNNANNN
+
$""!$$"""!##$$$!#"!##"!$!$"$$$"$$#$!$"!"!"!###$$!""$""""$""#
@r1357
AAGGAAGAAACTTCGTCGCTGGAAGCCTGGAAGAAGTATCGGGTG
+
E86$0A?3.'<F=B4+D,3?39';+7:'7'-8$*FAHH9B372!&
@r1358
TTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTAT
+
.4:<F3E$D484,99+D;1"$!A8DA'/+69#(/*/A6"A77/49.34G?7<70%6+A4>1>CB?@,$:27>H1F;>)%G='584<GF)->$-@4D78:!"6-)>4H*96(/)!D--/76GDF0,.##F##%:B=1#0
@r1359
NTTGATATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATNAATTGGATGGAATTGTTTATCATAAAANATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCNAGCTTGGCTNTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCNACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAAGAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACNTCGTCACCCATTCGATTGTTTATTTGTAT
+
%#')!+%*'!!%&)#))%%+$")!&!""$+$)##!$&*(!&#"'&*!&)%%$)&)*((#!(+)#+"%!!%!#+&+$)"#+$+$$')%%*!&&!!+!(("'"#+'!*%""+#&'&#(&")"%$)"#'$$$"$*+++)&*!')*+'*!%&)*&#!)$%)(+*$(+*"'!'"+###'##%&$#*&%'!%%*"(*$)(!"&$!(%&+!")*!"*)##)"#"**"(+$$)('%!''&$&!*(!#&$*((+))*($$+%(*+#'$$+#()""*'##)*'"!$%)+))("&**")$!#*('#+(%++*$**(+))!$%'#%%&!%(&''%+$#$"+$+"'%!(%#(+'#$*#)*$'"%!(*'+)+')&")$(#++)%*("'#+#%)#(()""!+!)&%!'("(+$!%"&)&(+#!
@r1360
GGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACNAAGATAGCACTCGAACNACGAAGTAAAGA
+
'59&!;,0H.#G7<%GG4/A/":0->65C50B#8E+;E7.>:D"E9=(G0(F=%1:$";6**3D'=BG31.:1!@F::*412;+!(9
@r1361
CNCGAACTGACTCCCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTC
+
'$/!$</)@!73*/+&;%H(+?/&C*/GGCG.D+H6AG$!AB3@#%,2<F3H7B.(>B%:>H'28/C@7(3F=+;
@r1362
GCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGNAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGCTCTGGAAGGATTTGCTGTACTGCGT
+
E"(8,D,'64?8&<F:2>*F8!H#,+'6DA)2G2D@=DD93;*8+B"1*);E;A,B%H#57%?!)B.19,,9,697-#$#+H>E"&!GB!&B2'5/39E?45:@58:=E-":/D8:&$=0#3C9H18>,#$7+8!8+,<(
@r1363
TACCGCACCTGATGNCGGGTGACTCACTGAACCTGCAGACGGCTCAGGANACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCATCTTTCCCGGAATTACGNCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTAAGGGGCGGCGAAAATTCGTC
+
7-0!019*(*+H57<#46CA%@%#6HE49#C%06<"?AAB%#,%@72!<:7/!%$%(#=!#>B!!9!442,4F>H>*@(-:"G>/&AH174#DH)%3AD-GC;8:58@?;!3'!6!);C,"+E18>/0#)>(*/G$**BC!&(8,7@@H46&0'*D#6954E,"$23;%DD#'C$346A-4:*9FA9?EH:"F#/8EH;(H%A,@-"/5<<*<:H&F:"FA
@r1364
GTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGT
+
412B&9@(#H(.<6%94:<G$0*:3.H'HH)8G64DB5$8HF?A/5%"1$'G'E5A)3(:5<@F&HD,@;.H9
@r1365
ATTGTNACAAAGGAATACTCATTCCAACCATCTGCTCGTAGGAATGCCTTNTTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTC
+
E<A$-&3):G8&&)4D8/"A*.20F1>AF,B)#;:,/52)G)3@!=&'F5C><.16"(00,)176&;'?<FB/(76D836/>+<.E4EB!@E?!6"D'#?,"#8,#:-')-34.D0/@(0%32:<H?03,+C@C"9$0.H$,!D"??>H.F<G/3CHE+H3.H4GD6
@r1366
TATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTNTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATGCAAATGAAGCCATAGGCATTTGTTATTT
+
E+78C=2!8H:6,*&+=:*H<),<A2C**18B)%+/5#F6'B<?%%((+:F+C&18H5=C*@7/G4"*#,#C.B,0EA;,)0;=+:>*-6;,A>:7@)FC<%,9#&@&'53G@86D0AC@/EB-1'"E.13$<8B
@r1367
CACGTCTTATCCGACAGTCGGTCNTGCACGAACGNCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCNGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATGACAGGTGATGCGCGGCTCCGTGCCGCC
+
2/7.#<8D6?!"3!<A*2CF,>#(,&!G%'B>'G>53!'71A7'2,?;6$%2"=267:3,GA)0':B1+:?!)*H!(9!0%(B=$H#80E(/E,0(4H<'9-=("AG7,'>$&/#C!;-/?D(=!(.@%=-9B-).#$HG-1)5!H@"#*6&)8H08D
@r1368
TCTCGGCGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGNTTACCAACTACTAAGGTTGTAGGCTCA
+
12=>D':=;2H-'-C'>*0;-1,>B=(GD/D>BE;0H<;-F/!8E0E1/F8;D).G?A5E9-D:*E6E!-&;(@8
@r1369
AGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATNAGG
+
,#B7-.;0!067::4:@*-89:%=.&B'8"(3+A%+:3C?/,'!H(!?C9F9054B,E8/8"/.'@**7'8@F&D3/?76GEE#GG0G6&1
@r1370
TATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTCTCCTGTTTTCCTAATCAGCCCGGCATTTCG
+
<)$#67A$(H&5.-(A"<(,,;&79,7@92:04$)B:@"CA(A)8A5(-<A8<-!$76E6"A-.-H4G-9CE+B;7(H:E7F&>D?EC$.C5B@!A$*GG8+C+9"D06C9:4*8";<1@=G/F,/@-.?)/&D5<)<E38(=
@r1371
ANGANGGCNCGAATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAA
+
'"'#!'$&"&*%+!''!"#&&)##*(!$"*()+%'$)%'+(!!!&!#
@r1372
AANCTAAATNTTCTGCACGNNTTGCCGAATTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTCCCCGCAGCCTCTTTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCG
+
$)&$)'!(!'$#&*#*)&&$*+*''((#)%)$&)$+!$))#!''&$+#"''+$+'&(*+'$*'!%&'&#%!%"+")#"%!(*$"$++'))&%#*!&**#%($)*)&)&+*+(!*#""$$*&*%*'!(%&$"'("$+')+++#
@r1373
CNANNANNCTCANGNTNNNACTNNNNGNNNAANNGNNCAACTNTNGANCNNGTGGCNGGTNGCNNCNGNANAGATNNTNTCTTNTNNCAGNTNTCCAANNCNNNGNCNNNATGGCCCANCANNNNNNGNTANNCNNNNNANCNCNNNAACANTANCNAGNGNGTCTNTNCCACNNNNNGTNNGANGCNGNNTNGNANNGNNNNGNACNCANNANANNNNNNAANNNNNACNTGNNNCAN
+
""#"##"$!""$!#!$$!#""$"#$!$!"!$""!$$$##"#$#$"$#$$!$#""#$$"#$!"#"!##$$!""#$!$!#$#!$"!!!!!$$!"#"$$#"!$"$##$!#$#!#""$#!"$!$"$!!$!$!"!#!#!"!""!#"$"#$"$!#"##!$!"""$!""##$!#$!$#"##$$!#!#""!#!$$#$#!!!#"""#!#!"!$"#"""#""!!!$!!""#$"!!$$!$$$#"##!#$!
@r1374
CNTNCATAGGTATGCCGNCANNCNTGNTGACANTNNGAACGAANAGCTGCGCCGGGAGGNTGAAGAACTGCGGCAGGCCAGCGAGG
+
&$&%"*&"$("#()#&("&%#("!$""*"%##'&!"+#)&%$+%+!(''!$"+"!$#*+'((*"+"*$"*'"$&$"#'("$$*%'"
@r1375
TCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTA
+
&'94/=?@%"-7$*27B36+#C>33<6&&;A/<<6H;2>*%+A(#;16:
@r1376
TAGCGTCCTCACATTTCNTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCG
+
<=7<B?'5/(%3%#A@('GH7)0(1A4E&8;A@F?@<&6/+$GC;31;"!@8)75D2!$!'!*CA#F<D=F>
@r1377
CAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATC
+
C8B<D7&B5.!HD2>*#503;-G0$D/?)0!:A#"A0>5G5B(95!AGD:3@$$%&&,@<4
@r1378
CATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTNGCAAA
+
A/**42=<8AH6?F03&7B!)H?02&(4115=-%5+3#8.-.AH,1$8&
@r1379
CCCNNGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATC
+
(&)"!+'%!''#)*'!)(&#)(+(%"!&)'+($&#'#!!(&'%!!'%"##%!#)(!+
@r1380
GCATTTGAATCCGGGCTGNGACAATCAACAGAGGAGGAGAAGAGTGACA
+
F5&>>"H'B,=E&$4F0E",@G//4>(<#E87*,7>*2)$#3$**/958
@r1381
GCCGGAGATACCAGCTTCACGCTGGNGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCCTGCCTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCANCA
+
>0B$D"?@1H9E$+#->$6"E?86=?*(;8,0&6"A*>$9H+":3237,:H+;8,*EE0@A(/@&/4F,'!@1@:(#:6/2*8B#2A1%0C5>%+#C<&C$;G7#.3B6>'G>>G09A><&.F5;FFE&7A6'(-%92799
@r1382
AAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTTCCAATCGCNGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTCACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGA
+
E142#3<4"%953B:F'8""#=2A"/6E1H20H@:%;&+#3EF4F-,HE)HDA<6@.0:5A,93B+09EC#9!&D7<1*H85(.E4'A2E490:;%>*@;$A"()CG%G!*?E6+!152F$-<F4>?-01/C.9)/ECD..0FD.%*B#(6;#G++;@D;:."C6=C#>*#,A72/G(1<G(80"2&7)$G1D
@r1383
CNNNTACTNTCCGCCCANAGNATCNGCATAACCAGGAAGGGCGCTGGGAAAC
+
!#!((*(#'''$#*)#$!))!&(+!'$+*#!#'(!)$*+##&")%((+$+$!
@r1384
TGGTTGCCTGGCCTATTACCACAAAGCCATTCCCGGCAAGGNTAGGAACAACAT
+
A?>1/>3D%';!A;HE-1;+7&$"@)=;!B%!H$'5%G;"?<A;C(>/H)03>?
@r1385
GCGGCGCTGGGATATTACGCCAGCGAGGACGGGTATCCTGGCTAGATGCCGCAGAAATGGACA
+
-*!0-C7:>1!D@H.607A($9%9D7)&C#(B*$5!://$0C-80(#36**%'3#67?$D1<5
@r1386
TCCCNGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATNAATGAAGCCGNTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTC
+
'*'*$*&*+"#!+*)*!&(*#(+&+"%#*"#)$)((#"&$"+)($#$*))*%#!%%)!!*!)&$!$#$&!+&$***((%*(*')'*('*&$+""!"+!%&!(+&%#(
@r1387
TATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCG
+
4/@01B2-8F*-29=*)=7/?0G-8!2@F!6G/".,A*81!8:1=H4&<'"H/FD$@:8A82=;7.$A?-;""0610!>&<?+)(.$!):55F6.
@r1388
NAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATG
+
$<6-%'#;$$'5(>E636.(;720)$B(A:C30+12>!>3C"4*7,46+.
@r1389
ACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGA
+
9F%@=,#.HA$;'"4(H+0A:/,:@!4'8!)&B$$4+DH*E$"3@CE,+980(7*'/@2!F=B9D2052:F-A<@>1?9FAH)16,2.=<16,+HD$1
@r1390
GCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACNTGATAAATGCAAAGAGATTCTTGGCGGAGAAA
+
2*!*58C!>'.<B5;/G;"7B):<(+E:'=+,!-+#A4>EGF+;;/C882!'(?7=.3"%7'2'F*5A/"E?=F!'6>?*;0+E5.)E
@r1391
GTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTNATCAGGGCGAGATGCTCA
+
(+D@,*1'12,HD+5;99D&,E4#BA('!#EC''7*7,E+/DFG*H"&;24>+&0
@r1392
TAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGA
+
($;8+D?(G'4DA'C-?67$*=E.C3+$9!:&ABG&G92FGG=,.$C2D<>%<B1.&"%9:G"(#",*%:)D
@r1393
TGATGGCCTCCACGCACNTTGTGATATGTAGATGATAAGCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCNGTTGTTTTTTTGGTACTCGGGAAGGGCTTTACCTCTTCCGCATNA
+
%;-5!+E:-A(565'0/4$?;%/7E6&AH6A6B-9;6H:5B"0CEG&BD=>7$G<<56:#&6$4,?%(,1)'G(560CGE!GBG&*@1?21@-'5!.%("=%F@7BB&H@63$/CD5*:5B)8"/(6-4>(0C71<:6?-:#2H3$:HA,F+E0,%3,2<:$+C<*.9:7>*><D422**/5C7G)4F;="FB')!G%H'6@7,3,7
@r1394
TGGCTAANGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATA
+
1<2'-H)'0:<;!%44@0&;!H/;83)6&72A&E274E3B>FF??H'7-A!E(A1%+69EH;!B;0<+C;2A$-/858&2.59
@r1395
TTCGATGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTT
+
A01/$F)>-9,@H*GE$C79E!>3DC(';BH<>.A(HD$4".?C2A:'C5B">#!"06A%*+-(5H<5?A
@r1396
TTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTG
+
+&("!+#'*'$#'#$''+""$*!"%))*#%%(%+$''('*++'(*)*#!##*!+!())'#")$#&%&!%"$(""#"'$($+$#
@r1397
NAAGTCGGTGAACTGTGCAGGCNGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTNTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTATTTTTTTCGCATCACTTTCCGNACCAGAAA
+
"''%%()+*)'!(*$&%**!%"'#('&*)&($'+&%"$(!(&$#*#'&+#(+!+)+%!&%!%%(#"(()%()$&%*#&&"!%"$*+$%)&*(&%(%))'#%$&+'"*$#($"'(+&%(%"+"$#$&%'$'#!(&#("*!**#%''('#$
@r1398
ACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTNTGACTCTGCCGCCGTCATAAAATGGCATGCCGAAAGGGATGCTGAAATTGAGAACGAAA
+
C"'H4%")58%C2'&.;D"AA:">%!;E<.F?;D9@620&$C=00?.@'<-%C4AF>)F;>?E&EG(%%<>,DH0#7G!E<D$+$%H/4E=:>H&,..4H8";-5"8HF3+1A=2?G)"',*(3F/F1!E8A5)0>6/EC'$E(?B4%".H&/
@r1399
ACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGNCAGCACCGTCGAGGATTGAGCTGACGCCGGG
+
*7-#18=#%&4**3+78(">2)08/?A<F/H4?BCG0>1%$01EAE!DG#F2,*%$.;;4%E602<0B.03>&D,8#D,++0,E2>HD#(7.=G=/;F3;8)@<=.")$5E,02!?=BCB-F491&8(=5)/3<C,?C%$E:%!,3
@r1400
GATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCNCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCANCCCAGAAAACAATGTATATTTTTTCTCTGAAAATAATAGACTTAT
+
1!7B"645G;*"4!+=F.A6B31/><5+"(0)!!D3:+?B.2-1G=,,0,6/B,!#)7)8984*3;'3<<9$4$B!/F5=('1"&96!/H+2$;$E(52BAE-?.3;!2F$&,)73,;67?8GAGH.EF*951!@!A0%A3BH3"56BE%F,3B32!>52'>;6(E"
@r1401
CGGGCGGAACGGTCAGAGAGNTTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCTTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATNCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAACCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGG
+
GF1.:6"#(-.6/5)H)82?B"#'359"3;H0A3.G=194"'G@<E>@=).0$(289*?<>+8322A()87B4)?"3C!'1!H@6&$(6D52-:94A$<AF!-$*1,0?0:4:2:5<D?4*,?-;E19"7.->G46:+C(<H&?5$H8:7?0"*-4F(>(-/9,0#>+$8G?;8#D2$"$4#27(DC+/$#0+3"<!/HG0/A0E!FE"/:9($/21C7=7C@H3-9,A85A%2%(@8>*E,"(';/3!*?20H<$3@*?0@*A"<B.+/,3;0A)2#,)<(+:F8B.)%1C+%E$)9*B4,#0
@r1402
ACGNNNTNGGTANTGATATCGCGAAAGAGCAGATTTATAACCNCTTCACACTGACGCCGGAAGGGGATGAAC
+
"!%"""(#*)"'#'""'%+#&*(!+#+$"!'#'!(%!#)%#%!+&#&#$""!*$%#$#&%!$($*'*$*++*
@r1403
CCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAA
+
/!%D(?;GD2B#999&.)A+)/<(26/9+9&@,$#2(=F&&C?=H?%@E07?%1D46EA-
@r1404
CCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGNGAACGAGGANATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGA
+
3G7H*1G=2,A.3=4-@,E98@;$=D,E?>D=/+>1+G,.G,5CC#**+/$"6,*6$F9(4/$5"<$D'50>+;4>-G/3F#'>*94@3/8H):3A*/-=E<C?-60:)C'.+A)"(A>96=D1E6D4!D19+4<82F(2/+,
@r1405
TCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGA
+
H.3!/>=!<;1:;52.-&6AF8FE'<4;FF9@9,04'(B?&:'.DG.;,8!D!23=93'$'6DC%B,'9&22=9"<BG&B%*1(3"G
@r1406
ATNCNTCNNNCCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAAC
+
*"!(())"!)!+"#!+)!$!*$'*'*#')&%'+$&&!')%+%%$*"*$'&+"$
@r1407
CCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCTGGTTCTGCTGGGTACCGAGGCTGC
+
C6;E;:8G=G=B4>1/$0>G%93==*!F==602)F.->-&:+='40C2#7&=-)D,B$:#10&+092""$8F8A.4-41/D?6E53=#D@-?+68#>;:CH")E$</:>F"@*B=,6'B.0%*)-$
@r1408
CTTTAGGCATTTATACTCCGCTGNAAGCGCGNGTGTATTGCTCACAATAATTGCAT
+
'#"*+%%##)'#*+$!$()%'%"%+(!$%$"'!(#&+$#%!#%*$'+'"*#&&'#*
@r1409
TTGCATCAGATAGTTGACNGCCTNTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGGTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGC
+
,)A=54>;'!@(E6!B=.&",4%80(CA0)9?!"+86"F@A=5.:9!7DA@0==2>3<+#C+5!F;+/D+B'7#6$1D1+0</C1H.*!((DA3+1"C6)8F?:H%1934%4H&D?',F9@,037C?H9,?3AB#$/?,@A9F9G5:$+7H?:&"C1*2?.#%C55%3"&E.8.-3"%HD48D53%+:G'G;,+>B!C:5F04+F=&&>)'1>B%%38.2(G,H8#BF:%59DF,7/$)85?+&.(8$<#'6?C=B0C:0$<:(*,3D@=$=29H9#8/E@,$.4A;&)!(2D
@r1410
ATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAA
+
<29?%"@:#EC&(,3GAB&2&&4B8?*5-$*F3D7%G,9E#);-("3>,$D0GBB*,(2',;&
@r1411
TATACCATCACCGCCGTGCAGCCTGTGCCGGAAAAAGAGGCCA
+
+'!"#&'*#*"&+)$+&)%)&+*$($!!&*!)$#"&%##*&("
@r1412
CCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGNGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGT
+
'::,"H!*&9@3.4DE!+&8'4&'G!@2-3$6312E+"A+1>/-G=97FCH1+5+&8H,!A04C6+3)5<#0D?&%(-27G4.!$-6/?G5B$%0?@.
@r1413
NCACCCCAAAGCCTTNTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATT
+
%)+#+%$"+%$"'%(&*'%)!*!"#(%&&!)+!+&&&("+$&#$!!(#"*')''#'#%&''&%!%")#$"!+%+%*+#'%")"'&&*#)%&"+""()*%"+!$'!)&$!!$#$))$!"$+
@r1414
GAANTGACAGNGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCNATTGCCCGCGCCGATGAAAC
+
'''"&"$&*)!&+(!#&#*%+!)'###%!)(&))"&"##%&!"'!)(#%++$'#!*)#*$#'!+#!"+"!+"*$)$%"#(!"&$''*#)&)$*$&)#!++
@r1415
CGGCGGGCTGTCATAACANTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCANTGGTCGTCTCTTTCATATACC
+
8='547.)F<9C5%*.!));3>?D&+>B5=<'"@""F8$+,6*-44,$,5./+*&52?/?4"<2=;,!./$4=>A.4-D(-E@39'<C<$/H"H2/)#E'(,8<15H.>9>.:B3H)?*."0<:"9:C4!9:$)2+EDE6C<(>=7CCD<AA*F$(3%+H#8E(%@'G%2C%*1;!(1'6H(A((9E='.05=!8C0?@"5/10</FD?8G#655D&G99
@r1416
TGTAACGTAACGGAATNATCACTGTTGATTCTCGCTGTCAGAGGC
+
G%FD$5>7/='5)/,!8DE?(@:190<.*'A;;.=/8)):-+%4=
@r1417
AAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGC
+
+),1E8G@(322:9B89C?::%:=G!C1H/H:FA9=.=.>HD/+F"(2&,"$1"590D<.'?4"(/!?#%($C=%A(/&10#
@r1418
CTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAG
+
C?$7?F(*&+C740G#%?G-=--"GA7+'5D>#"B6.6D(E'F0$'.GC'7>$#67+$)4.?C23B$>=?%6'A@BA-*=041G*&6=-#!E6/40G:7937$5H5<!;56'E:)"&,:BD8;>D@
@r1419
ACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCNTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCNTGTC
+
&(+##''*$*!#&"%!'"%)!#)$#'&#$$*#))#"#!*%#'!%('+$%!%*')!"(*#)++&)%"*$'"&"'%'*&+*+))"(#+)%"*#$()"%)"))#($!
@r1420
GAGCGACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGANAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCGGAAGT
+
230*,!,6<E.FHB0(@.G/G+G;46F/)"/9D+57@%!!>'F!6(":?G/%<-42-*FH)D49=#F;3><7*C%H106?#C120H>+@;%4F&8:/A>C0>/DE>3E41,--!75C>G*@)5..7E(BF=,'0:/$(,4",@!H($)8)?3%BC>8+6H6#79(62>1CG3!5D983D%D*
@r1421
TTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAA
+
4!#:2"##E)/3D<'(#73AA1HA,->A?1D2EB%<*1#&=9!BF:A6
@r1422
NGNGGAGGAGCCGCCACGGGAACGGATAACCTCANCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAA
+
&$)#'*)+'##*+'$#+"#&(')$+#+&#%&#+#$!%"("('&"$%$((&$%")%!+'$)))'+*!%*#"$!)*$%$+'%)++(!""'+!'!#%''++*"")"'+")#&(#)!)
@r1423
AGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGNAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGC
+
F3&0)A!CE#A4F;8,DF;.)A2:#@'24E,6D+-@D7%(@&:;<A1C8C2:@)2.%5,:F=?2>%%?530AH;,G*8$,G=9H8)=<(CGEE:F&)9FAF96,0H)-C&H"@<"!&D32FA'+H*)D.(,"0D:D;@5%G3?:(*,.,;!,$4%:E<4"1@.%*;,0C7
@r1424
NTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGNGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCA
+
,$!%DG*;1@*G1/96H,G26D#*4<&-"71<>+<;'<:$"'-)&7!<*8G&3!,?:"*<&2,2;4C@&<.H+:6)C("08=9,CAH#9>)<:6;(2#8>>%*7C"0$A#*<+G
@r1425
CTCCANNANGATANCGAGCANGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTTTACTGCACCTGGGCCNTTTAAGCTGACTTTATGGCCTCNAAACCACCGAGCCGGAACTTCATGAAATCCCG
+
)$)'&#!$*'"%#'!%$&(%!+!%""%!)#%*!++!!%$"((!))"**%$$"$)%)!++%$)$$(*!!%%&'!)$!"%$#%!#(%)*!*#)&)$'#+""+%")+''*&#"$&$$%%!%(!#")'&%%+#$(!$""$!%!+'%)!#*$!+&'#!('!&")!(*
@r1426
GTTTTGGTTTGCTGGCTGTCACGCCTGCCAGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCNGTGGTTACNTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGC
+
+$-@@A,9B5%1/:.C<>C45#+2>36$5!6<$%-H'$++#?.?'-9E=?%/."A09&+H:+F,'C+D&G;)B!'+5!5+41#&;%>76@&/(@97@6/G"B0(9'!=E%5G377"8@=)!F./=G)EBD)@-H+=#-,-7(,=+!%#72DCG#E5G!%4/:EGB=6>:-7%64.-.BDFAE>):/:;6G$A:5/,
@r1427
CCCGATGATGAGCGACTNACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCCCAATCACAAGCCGNATTCGGTATGGCTGCA
+
7)&-?$@/7@;A01?-4(83D9@0EFE,CC>&*#?1@DA!0;E?C(*=BG40.!@A9;>"FA.-F@3!A7+<%/?,@"3,#>7D80$A:(99B60F4-FBC(*;,&;757*!
@r1428
TCAGGNCTACAACTGCCACACACCACCAAAGCTAACTGACAG
+
97+%"-G47=$#-C;2:>8-5)E27;3(3<07D!$D6E!7%9
@r1429
NCCANTTGTTTGATCTTTGCAATGNTTTTTATCAGAAACAATATAGTAAATTAGTTACACAGGAACTTTTTAATATN
+
%#"&+#+"#!$%+++'#*"!*$!$'&#'(&#+&**$('$&#$#(%*#**#*!+((%)!"(+$&+""%'+*"&%((%&
@r1430
AAGAGCCTGAAGATGATGTGCTGATGCAGANAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTA
+
7G"7<-$E4.G)1<D<F+5@-#DH5<A/&!&3.(D4&=!*0;(/;&04;(!+#!-':"D%)9!3?5;/AG4$D4&46+/4")?7@=$!11::0>9<(.=!7?#&@:H%/>'<.DE-4&G1F240(E>"
@r1431
CGCAATANCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCA
+
C4936D85'(A"D+7(4/"(:%-<B$:B,&8$'#>=A%-C++46C92+23F24B#A,$@/A
@r1432
AGGGNACTCTTGATAAATGAAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATC
+
*$(&"''")&+)#!%#$$+!!#&*%'*#**"!$$&"&+'(%($'))!()$#!")&"&*%*!'+*+%"%'+*)+#)*+)%*$$&(#$%"+**
@r1433
AAGCTTGAAGGAAATACTNAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTA
+
GA3>,+B%0<H1(8'9B"4;7!H.+=%#GA#%454H!$-&#;CD2=@-'D7$>77(&AF59<$)/2;'28A6"
@r1434
GCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACC
+
G'!C,40+.9<E'/%7$<+<G>'%@!;;+H&57:F1';D:"<D82=-:>D-:E+.E#2:/48$,!
@r1435
TNNNCCAGGNNNNGNANNGAGTCNANGNNCNGNNGANANAGNNGNNNNNTNNNTAGTGNNNGTTGTNNNTGTNTTNANTTANGNAGCNNNNNTTGACCNNNNATANAAACANNNAACNNGCACNANNCTNCNNNTGNAANNCAGCNTCCTCAGNNCCANCNTNANGANCATNATNGTGNCCTCGGAGTGGGNNGNCNAANCNGGNGGNT
+
"!$!"###$!!"!#$!"##"$!""$#$"!$!!$!"$#$!"#!"$""!#!!"$"!!$!$$!$"!$#$#!$#"#!"!!$!""!#"!##"$##!!"$##$"$!#!$!!"$###$"!!#"!!!#"!!"$!!"#!$#$""$"$$$!##$"!"$#$####""####!$"!#$"""#!#$!"#$$#!$$$"#$#"!$"##$!!$#!!""#"#!"!!
@r1436
GATAACAATTGANTGAATGTNTGCAAATGGTTCATCCCGCGTGGCGTGA
+
+&)("*!&%&)")"'%)!++!'**"+$#)+%+$()'%((!!'($(+&!'
@r1437
GGCCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCGGNCGGGCNTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGA
+
#!>A#/A6)5<&,@#,+61$/(-/A!-0=ED2H=#?67%:C<#6=535!$3&>G!<:!:";)<G%=@6;71%>%%+"G:9D2(:A$3!""+C.$H@/0<0H8@'C',"&"F69>6.+23A@E#;7E6$8)4G;8?@*6+1#4('-!G@"E/H*64,A;D4$.</8$H8.!5%=&1@(,0#3#$08*@=#;3$,!G0(>@4G"F(,D6'D9;;FEF8@9-5#?E/D>0=83:-:.,E(-+"-+8$5#H>,*F!BF9=7(<*-H&362=(;.9*,
@r1438
AACCGAGCAATCCATTTACGAATGTTTGCTGGGTTACTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATG
+
*4ED>F5'G(9D"25)4<2B6<7#6-)>;6%9+D,B<7128"6#.EHF/$B2@3<1'054FA,+F=*!G1587&<#:F2!2G8.>2A3+CE&'!.EG&;3"8/(9#-882.7"@+.=A1F*7(4
@r1439
GTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTNCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTN
+
4"BA@?@60&F<96B6H8EF>C/@>::,7.#5,E)A"64)9)G4&21809'0'D354)$'@9+0.B3/E(-BE%%/.42%B.'DB0=CG'!)B#="2:20@GH-/')9*1G&=-(#7<!C@9(,'2-F(B/4+3C=1B,>;5>87<"+6-<A126.2;)(.?%53"*=2">2+=6/>?6E'.>F*.C%A*(G>>133&.:*0C)/7<*.:$%C?$-74C7AFA!<42%8H/#F!)<G?*04;?
@r1440
CCACAGTNACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATNTTGATGCTCTCGGAATATCAATGAACGAAACACTTGATA
+
/=6?$4;&E(B7<.>*G%DA@F&6*).>1,0?+H/"58#)88&3*#%%8/!?H!#*/%/!!A)8+'6(G2;9.FE)2H7)=#B%*&H&@6;'F@&F"0;&"+31)'=#997H08*%9,A2:$@33'G*HE4:8AE8@$=A/?9&'*;!8&6(2)9!%B@DB3$1E
@r1441
GNGAGNCATNNGTAAAGGAAGCAGTAAGTGGCATACCCCGCGCGAANCGAAGGACAACCTGAAGTC
+
"$$##$!(%!%+!!)'!($(#"*%"#*!%('"'*%#((+'$()++*!'$*&+!+%*)"$)($&"$"
@r1442
GAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTGTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTNCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGT
+
-143E-?,:3:>:F.A@</D.B@&&8(BE#&G()<<)(2/>"99#/3.FF>/AH3=15?('2D5:=3*H182:B$(C')#29CA$+,!'.1:/@".6=A.;B+.AF,8F(@D.B=5:$?"@!/?4"%E)0+A"22(<:/C4F#HFF2))94""B.!*F#?"6,&&=&24"G"08B&@%(@*-B?9A/%'0G><7:1!.AGF@CC8$,/24BG%?.E#A#46,9+AH90D@9A3-:%$04-$F+2-!>A6%&38<FD9%33%DBF-.09F&+E$B6)/F!E1D/0&44E3E6C98'5)BBC8%"2&H=-A&#5AEC<#2=6:%:4)<*4=/%./,H)02,7$C+>/-6=C?&?*>&+':!5-4G04;%8-)7DC9:$33.
@r1443
TCCTTCGCCGTCACCGCCTTACCGAAACTGCTGACCCAGCCACGGAACACATCGAG
+
>B/2?@DD4?9$=14&G8?:G(+;:A5#3%&;9$C<D,-D)"80!(/9"EFE=64>
@r1444
NACAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCANTCCATTTACGAATGTTTGCTGGGATTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTC
+
"'$))$+(#"%'#($!%(&$%*"("("*''#**&'(#!!%"#)'+'#!(&!")('+#!)&*!')%')(#"'%(((*)%"!*(+'(%'&(%+'*(*)+$'!%%*'*"!*'+#+$("#!$$#!")(#$($&+%%*%&!$*$&#*&"%')"')+)*&(("*+*)!"+$"%$*#&*'+($#%("##
@r1445
CCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGNGTCAGCANGGCAGCANGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCG
+
;77'@8>63<61(0.-@DH86%1G,4>4-4B.?7B>-:10D0C7$C#$&9H1#3?)%398$00B%;+$2?#F(8C0*;G%HG':8%3!>5/6D@?61FB+:GD8E.F$D,D7F-*#:*"%5(GBD+:!5.67'>/#AG6>DBD,(-!6489#G0B5+;&>6D*@406@B"
@r1446
GTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCCCACGTCCTCCTTTTCCTGCGGTAGTGGTAA
+
C,/2G&>"E#)8*"6:EH(4&FB!;G,)2G/*.A>+8>$=1EE+?#."44E,*04816DC40C>$H*5$9)FFB9"F!"B-8:>,)>2B#D-;B!,
@r1447
NACAACGCCCCGGTGCNGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAANGTATAGTACTATCTTTNATGTTCATGGNTATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGC
+
(#(+!+*)**'+%%$#)(#%!$'$!'*("$&!$*((#("(#()$&*&&$)%&$+%*)(+"$$"*%(('*#+!)(+$!&"*"*')*$%%&'%$&*"(&)##&!)+)!%"*"*'*%#(%&)))!("&&'""#'+*"%"$!*%+#!))$*+*&*("!&!()"&()"%!+$+*!*#)!+$%)"#+#"!$*"#%
@r1448
TGCAGGTAGCCAGTGAGCNTATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGANACCTCGTGGCTGG
+
100%:'0@/3,?<33*D(/"$0%,C<#4*7.A?)</G".G@6D=9?352!*75DHA9E$@:"!<%D'1?G$%;%2<G25%/'';
@r1449
NGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCANCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTGCTACTGGTATTGGCACAAAGCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAAGAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCTTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCNCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCANAACGGTTTCGGGATTTTTT
+
&<E9<&<?!;6D)7%DAC!61.:D-G./H.2=2!%&$$=3F8<%B)?>3%@*(8;E&(;FA,58F-!8FE'"++'*<.1'BEAE62@+$H*3B,)A"E<$0@!''#/&%+;+-?.2>=;E=(;4%C::1(+C>-D:2"1;=&1:-/6@16#7),5)&$A:*;6@0.C!2+70@A3$DA.'/A4584C/+>.;F,0+.)*E8F4*#+>G"'5(43H'47";*$B;4=1!C&%F;&%6&DA3=6!?>F>8#H#=%##2H"1A<>BF82+"G<$,?6<9'#)?AB)$)(E8))(1(B(+E&A*.&-42C-B!:%@"F,(-G!%)G#0./>-!1=>*H@5A;B%!(7D7=$"*C'*@9E%<8=BA&3C'GB5GDG9:)-,E+5#-C1%&(6=>-!:-04.7CDCA-$H0%-AD1A<1:H543#!=5C,4E!,F%#BF@2<3%F:7?:@?#@4>2-89!6B(!>'*7)9BD:7#'D366(/6=GD!4*F6/<?1:%"A1-31H2@
@r1450
CAGTANCGTCNTNCAGGTNGNCATAGCCGCTGGCCACCANACTGGTGATCAAATCTGACAGTGTNGGGATATCGCTCATCACCGGATAAATCCGGGANTCCATCCACGCATC
+
''!('$#')%&%")!!(*$!#*(%++%!%!("%#&)#$"%*##%*'+*+%''"'$&!$((!+"(+)%$((++'+&)(#"$%*#"')"+(!'(%')++"*"$!#)#'")$)*)
@r1451
TGGGAAGAGAGCGCCACGGACACTATGTCGCAGGTAAAAAGT
+
)+!'$)*)'("&$(#%)#+%%!+!()*)")'#&+()'(%("$
@r1452
CAGACCACGCTGATGCCCAGCGCCTGATTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGNCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAG
+
<4BBD(C/-D3B;BC($2GB:DD=5(1230::>A=,?51+.@2>E=A)!&5>.$E3?*)"#C74>,(+CC+?F3/!%*-'1?%.+*<?!-$B'/6#86;5+;1A2*AA80>9**!&@:F:C<(/AB'2ED%E-?>%5$,2+=+>EA87+625<$6BC/-<7B2*7:BHD@&*177/1#"1+G;H2!?.DA5A-)F+;A*;E8A&E399!H$C:1#@6A:>2F0/
@r1453
ATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGNTCTTAGGGGCAACAGATATTGAAG
+
+""$$%")")++"(**!%+')+'!*($&+())%&$*$'$*!!)(($'+(%'*#'*%!('$+&+$!)'&"$+'"#)&'%%((+!*'!!'%!$&*#*%'$%)!%*$*(*##!"$("#!##!!&')()%%'"*!!*)!$%(##"&*))%&!(!'$')#($#)+'*$*
@r1454
CAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGANGCAATTTCTC
+
/%<$'F4-(&%(?B3(-@+:=71%:@.F=E*?C)6@:A6H42!9+C'9;
@r1455
CAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCTTGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTNTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTA
+
B,?,09'$1$G$&H@G->$9=B-/B>9,;F;00!?88D:>:G55A;#<,20"1510<.$DG("BB$'>5A-;%>D0B9>8=?%=G#(>58:E#AF4/;$;59*-:0:*'><8(*881(='D4A8/@":&D:/C6?"%8EF;G<:1"-3?&>).?<$3-';-!G)C.-/HC9..E806&$&.FG@*"#)@B2#D/H1>?#)@=663!;*E137/:,8(7;D1C!(.?1;B)"41+F)'48,<87E;"<-2;,H-D&#/(9&-)G+A((6;@%=C((B=10=B1C
@r1456
AGGTGCGANGAATCGTCATTGTATTCCCGGATTAACTATGTCCACANCCCNGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACAC
+
2:/(/F$=GG%7->%,>.9>'F*7A,%8B;F7.3#1/&:16G=$G'4<>3/4(1">$<EHECB9*6"8C&CD2'4<7GE9>%=-=H1=(G/<ED>B/"%2E8>
@r1457
GAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTC
+
<AG>C:&%4C>".'=,59'$565=9""=E37%;D5DE@./+6AG69="@;;HF#<>:0*4+3+A/5G
@r1458
TAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCA
+
HAB7$25.G9=8"G.8#F-:/H+F0EB%=E;>;-1(C9:E9@.GHB
@r1459
AATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAANTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACC
+
8'32.*(0<(D3*8$2$4C7?-(<<56G/&&;C#5@0<A:"#8/5?C85E-4<.C&$)+-1=>2C?(-3-6-;CEAE,80@(@(=CD71E.0:%1?;?=#G">)41.:/':'G0<$?D?H3B"*2A7.E!AG@F"9#=B@*8<<B4,03G&'2>.23,!:#:@("$<F:%572<&3,$((7%&&6+A4CH3G4H$%1C=6AE/
@r1460
NTTANCNCNAATTNNCTGACGCTCAGTAATGTGACGATAGNTGAAAACTGTACGATNAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGC
+
'(!&##"$$&&$&!&"%+*+#((!*#!$%$"'("(&))"!&$'()""'*'"()!("$'%)!#+$))'(()$+'$'#%(#''((")+$($%)!!)())("%&'*!
@r1461
TGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACG
+
'C(-()2F$2G9%GF"!7/!@F#*2-A2FF4HCH<61=@)!6#E$0&@C-+7#78)HGA<6C559:>$6@(C08>)%!&>$?0.5-/2
@r1462
TCGATACCGGCGCANTGTTCTGNGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTT
+
:D&H<(A3/1)0B=8@#+A;9<3B3.84%B04@.H6HB0):B,&8+7($9?E)8>?!8FH'6&=56B?-5&3+1HA&*C%H,,7+DC/8E&@"3%3D%7F1G0@)(7C87#>>$?7D>6.4/E+,G&C#&:;9($4F
@r1463
TTGATAACGCCCAATCTTTTTGCTCAGACTCTANCTCATTGATACTCATTT
+
.7E?=)8;84A!:E50$H078G6))7=-9C05D,-2,%>D,6!H@9/2?H7
@r1464
CCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCNTCAGAGAGAGGCTGATCACTCTGCAAAAACAACTGGAAGGAAC
+
AA?455!C<$("G8(=;/5144)62.GB*)@9<C2CE&B"@!H.%52.%>9<%#<;1-&?27398"74*;*;()/.>@,>&?H
@r1465
NNCATTTCGTTTCCGGAACNCCGGGTGCTATCAGTTTTTCTGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATANTGCTAACAGGT
+
"$"0/%)0,B-;G1A,1;11E*%/0*!1C63%2D6=-;+**95A?:>=+'1GF8%5;):#559(!;1(-><3GD&!-D)2"?/1HD<#9'&#8$H%F*/DG%*C:(&'6-)&$.*"F;8!A(9
@r1466
TGACTGCTCAAACACGGAGTAGCCNTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTNCGGTACTTTTGCGCCTCC
+
'@8(29-(G.!*<@H)%BE'AC;6G!/4=F<&&B.:E#HF>$;F'(2.1H%=#;4(.!F>"H5<390H>##-HG:<(%/?0:G3&H%>C*,6>>,0
@r1467
NCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGC
+
!F19(/.1<#,FG*H58D.1+=';.8F,D<.<55),C>58>%D9@21;74/8/E#D1C8?/()HE&).%0C.35-:&;E0#86==/E..1-,.9*G+,-F6<!D7"'H5;9@)G'$/EBC:2A0AH&GB?6,&=H%C%H78%.:+1;84.7G32,?%6!G-67?;+"6&D?;);;/$.1*0F&?62"3H-9ED0?19-:/9B#B0H<;B-B=B*+.%!3A(5>.02:1!?!$E2<"D@C2>B
@r1468
GAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTT
+
A,6@(%4G"7#(A;*?F<#;D&/A.'(#-+E&/%,$:@9#*1'&
@r1469
CGNNGCGANCTNACAGGTANNNCNGNCTGCTCTGAAGGCGGTGTATGAAATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACCGATGCGTGATGGTGGCCNGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGNTGTGGCTTCGNTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCCCAGCGAGCGCCTGCCGGGCTGAATNCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACT
+
'$##!#$*%"!%"&$""(&&"")&*")"$%%+%%$"(*!"#"!("&%$)%%%#"!*""&"#)&!"$!&')%+)($*+%##"$$$%"*%(%''(%(#**)*###$"$*&%!'$$%()%!)'#))&%*%'&**!%&$+!'()$%#"+&)""(!&"$!!&##"+')+$"'(+'$*'!+#$+)$)*('$)("&+!!*%%!$+$*%+&%'*!(&&%(&%+!(#)$&#'+*&$!$)%*)'++*'$&+"#*%&!'#('#('*'*)!!'&&$%&!"&#%"'*!"'#'%*""($+%)'!*+'#&+
@r1470
ACNNNNNTNGGNNGTNTCGNGNTNCCNTTAANCNTGTTCCNGNCNTCATNANNNNTTTCGNATCANTNANANNNNANNNNNNGNGTNNNNNNNNNGNNNNCNCTNNGNNN
+
$#""#$!$#"!$#"$"$!""$!#""!!$!"#!#!$#$"#!!#$$"#$"""$!###$"$$##"$#$#$"$!$"""!"!#!!!#!!"!$$$""#"""#!"#$#!##$##$#$
@r1471
CAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTNCCTTCNCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGNCGCAACGATGTGCGCCATTATCGCCTGG
+
)3'4E?&54FE,GD6)ED5-F>9D=G0%=:%3*#>-+08&D.F6)-0%96!!-1DA:0($<A036&:7=:$@@052:0;AF55,=?<6&33;A*3($?A42C<$#@7$!7-(=$
@r1472
AANNTNCCTCCAATACCCGTTTCATCGCGGCACTCTGGCTACACTCCTTAAAAACCAGGTTCGTGCT
+
'(&"("($!&+$'#%#"$()!&'!)*($"&""!#%!'!(%!)&#!*(&$"))(')*#*+#$#&$)%)
@r1473
CCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGAT
+
H#6$2D&"3BDC8F9=$'8A/$3EC60!?D!>GEB;07&7C022<9G<>42)C.G59E!78,;+?6*=9;?!828C<-0@:
@r1474
AAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCACCAAGGCCANTCATGCAGGCCGAAAGATTTTTTTAACTATAAAC
+
.$G8"'1D#7;,0D1'>4=")2;H&%8(=3F"119"3$E'3#"HA24#6&%6-9@2:)AB8+G5;(E*?&+A!HG/<#.;,,G<1DBG:,GD('C=@E7"B&<C4D86H#,.$/
@r1475
NNGCTNTGACNANTGNGNGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTNGAATTGAAGAACTGAAAGAACACAAAGCCGCCTGATGGCGG
+
!!*(""$&**"%"%%'!$+$)!&)'(&+'))*(+"'$'+'+'&$%#"$)'+#)+*$!%*##*%++$*(#''+'"$$%$)$")!''(#$+(("*"%)*!$%
@r1476
CAAGNNCNNNTACCAACAGAAANTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTANA
+
'(&*!!"#%+"$&!"('%#*"#)""$$)$(++)")!&$*+'#+)**+%"!+!&&$'&#$#%'"#(**((!#($$
@r1477
GACATTATCCTGCAGCGTACCGGGATCGATGTGAGANCTGTCGAACAGGGGGATGATGCGTGGCACAAANTACGGCTCGGCGTCA
+
B<E,/=:HB-=AG1/H%B:#<9;HA(F:*.0,<#)&F>C!F5F6$"<-36G$A2DD1>7@<$->EF;&3C;:9D0G>+EHC&$?+
@r1478
ATCTNTTNATTTAGGTTAAATAAGTTATTCTCCGGGCTTCATCAAATAAAGAGTCGAATGACGTTGGCGAAATCA
+
)*+#'!"+)&&)"*&%#)!#*")$+'+&#+$#$%($+"*(##))!(&)+)*)+'$!$$"&%+%"+%"*"$$)!(%
@r1479
AAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTT
+
*D@GG4(:79/!B!.0)-,@7#D:GG5)=0HB'A?)G>+$G#,+/1,/H>E%>4$
@r1480
NACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGNTGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCG
+
#A'#;B##A,=.)<A-B-*9/HH>A:178B2)1E=B)*:/#/.B#9$9&)0$&(C97"52,='H36?)HB+9E<$E1((A38E<81''&8@F$5?G7H7A%.?5.&0=6F43!<5@%@,.$5?13(E0"223@?&42AAG#(
@r1481
NNANNCTNTNNANCNNGNGTNTNTTTTTNNCTGANNNNCNANGNTNATNNTNTNNNGNNTTNGNGNCNNNNNNATTNNTNTTNNNGATTTTANNANNNNAATAANACNTNCNANCNNTNNGAGGGNANGTNNNAATTNTGNGGNTNACNNTAAGCGTTNTNTGANNNNNNATNGTTANANCNNCNTNANNCNNANNANTNNNNANNGNANANTTNANCNNNNNNNNACACG
+
!$###$$""#!!##!#!!$$"$!#$$#"!!$!"$#$!#!!#"""#$#$!"$!$$""#$!$$"##$$$!"$!$"#"$""$!"###!!"!#$$###"!!!"!#!$"##"!#"$#!"""$"#"!$#!"$"!$"$"###!$"$$!#$"$$!"!$$##"$$##"#"$!!!!!""$##"##$#"##$#!!"#$"!#!$#$!!$"$!!"$##$$!$#$!""!#"!""!!"!#!#"#"$
@r1482
TCNGTCGGNCNTGCGACGGATTCCTGTCACCCTTTGAGGTGGTTTC
+
("!)!)*(!(*&(+*$%((!#'"*(%%"%'!($&%+%!%"))+("+
@r1483
ACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGCTGACCGGATTGCCCCTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAG
+
.G0>6=!A%91A9,2(#H=6=E<;5?D7>,.F(9,=8>-#;&<"H:>?.)#0&<AE%2E'85!G2!-.(2@H=31@AF/!>GAC3A7'<'!7+'6(2@@A6?@67GF*FB<<07
@r1484
CACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACTCGCGAGGTCGCCGCCC
+
F))?54"F8*2B9*5BC,!=?#56D?);FC-*C2CHG")8(3):+9!C=+;2D&G<>;72';C=1''&8GFFC$H6.(339>D#H22(28)'#(8'!@1"F$+0+.+20*A0D:F8>+=*4.:-+G6
@r1485
AACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTG
+
$*#+(*&##%(&+*%+%)(('&%""&&&'+&$'!&$)**!#)($
@r1486
GATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAAACGGACTTGCCTGCAAAG
+
-,6?ABH>$3:@>#BG'0F,=(F:<6"G93F-D!D9.>E15%1"".*!H@G"C?$"46?(A%HD/B@D9$%&1<97;<<.B',(66?7%?;2G9&%C(?63(<7%HH9'14=#*"
@r1487
CTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCC
+
E4*EA&5G12#<8(C#6&3*33;F!/B#59A0B()%#B#',&*&&30E>0.+/B3.F<3=093(0H0C/DDC+$=:3-&B!%.;CC;4:8*<,&)29"
@r1488
CGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGG
+
-(D1D/?333<2+;-*@G@!&H-4BF<A;DD>6*G.6%7$'H!9>"$9>F80A(
@r1489
GATTAAAAAATCTGTCATATCGGATGTGGTCGGCCCGAAAACANTNCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAA
+
-6(4@?434%(@FG)7/>;"+F?+F%A+2;30,H-"0%6-=B;;9->!!.D?1).+F%'#9F+9>*7,2*(,4H&:>"2E=/%1B4!"-*:D@&?&B;!=1/)-H5=?(7=/7'"5">*-C)&!?0BC
@r1490
GCNGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCNCTTTCTNTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCT
+
1:&@AH"@%B(%C@-?;>29:(?55*%<"C"=+9@%"&H>/476=&*&BF**;C+$6'->61+63()6/;.;CD"'%6/+BF3$B)(2!4@?;?H=/DBC0:+/-G&>8.5)8/)C1:;8AB
@r1491
TGTTGCTGANTACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAG
+
)3=CA,(+$E0A)#:3!B*<+2?4'E&+@:,?7$+)3-*!%C%@%*398
@r1492
ATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATNTCTTCGTTTCTGGAATTGGGCAGAAGAAAAC
+
6F8G<C!+0;>CBA/C@0E'AH?>"G;6#F3>'+>CG78#1BHC'<$89/D,:6"!G5*>7B*-4020.+'$6%+H+"/(1A5!A"=9(&-H0('.&AB$)91=A
@r1493
GGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTNACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTNCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCTCATCTTG
+
:A"BC:#@-.?<47$3@!<(!'8C$7,'B*+B4.")!B=G'DF36HFE3>=535*%'9'2'E()E5+::*H;C';19E'$"8!3&950//G1D!<)"F6+A2=995/!$AA1;@"H=%C.9.0?#;B>#70EG&&</8;%G"&>:>84:B89HF%CB-<0''=?#:57?1A$D5'?,,!**E%)$4>0F%0##7*7)0'G33=:2>EE9E;46$(3"'8)$;107F3
@r1494
GAGGCTGCGTATAAGAAAGCAGNTGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGNCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTG
+
?"<==0/909;*B,D9&H2+!(,-=.02"6#C*4*53<:!)84,9#?/*$AH)66!C49$/B'2@G<E7!*@B1!-<1$3G()$C4CF!,)7=*31C!7=G8H@E#2BHD,7A0&"$7
@r1495
ACGCTGACGGTTTCTAACCTGTACGNTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAAC
+
1.+$F::F3/@/0;D@$0&F.1:1(94<:7#F=!%(<H8%#&7%8-=6E3@?67+*45H/#0"D#);*;=;!?&BE&?2&@-/A>5!G*>95-.=.)<7)*3ED8=#?#2>E/A,.B"B8#4-?.*:#2<+D9&5
@r1496
CGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCCTCACCGGATAATGCCAGCGACGCGAGTGCCTCCTGGG
+
.12=5$F,4HE(9%<%3<#4!*70%F>:==H@8#.?&2>C$#D5'!82EE"D&63457,.);$!D:H6)E%3:-.CD?.<B"&$#%'4?(1"#".</!69;%68='=B=B-:C(D;!/3;:'5%A
@r1497
AAANAAACCCCGGCGCTGAGGCCGGGTTATTCTNGTTCTCTGG
+
#*$#''%%&&+($&+%#)"(*'&(#")'&$&%&)%(%*(&#$(
@r1498
GAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGA
+
A)1C2*>62<>%'09$35E>1-9H$3")-6"!B<,3>9./BG/2:HCCCE<H$1<G4AD$2-?)&&@.H-E5)E&H3C%4C7A4?7<#:>??<8+D12,9(*<,3D+2FEH?C%D2##>)=)8G$30;."-"$-:6$2"58$7C)#6G4+,0&EH#).7/;@6B>
@r1499
CGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGANGTACTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCC
+
6D-&18/F6<4H%$3#=#8:/2*'-=H@"$/,-''H*+>696)0F&%.8%(!>,9@)%'&;B!F@-2;?-E+CA@%32C:4:';5#6@@B17:;:2B(5?#66*+86)C&FD5%%="G&6&8*89('#A<F:6.8+0.%'';+1=+?G@DC>@%%:H*24*..4H*!E(.)F6H9&@4?#"4%-%((@>
@r1500
CTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCACCATCGT
+
7,>(466H4-*3$#"%1%7HB%&""8*-=@3%'3A@D5D!A<AEGC5%>+G69G15:&&B(%D?F08#C"3
@r1501
NTTGCTCCTTTCAGTCCGAACTTATCTTTGATTTCTGCGATCTTCGCCAGANCCTGTGCNCGATTTAGAGGTCTACCGCNCATGA
+
.8E4C2H@-G*9>*0>:""-B7/?2E-'BB7;'9)$("3;?1</".2!G-E2&-=H.F"%7984-#/<B7"D--3BB<=8"1H:%
@r1502
ACAGGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGC
+
&)%+(')#)'$*)$#+!&)*&*&!+$+!#"#")&%$'+*$"!+
@r1503
CACTGGCCCNTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGAGAAAGCTGCTCATACGANA
+
'0C=.!@:-D&5-<B+:#(C.#:<9+3BE;49*7(53H5/>>$*<4:;@3C19F?,!):<)86
@r1504
CGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGNGAGAATAGGGCGGTTAACTGGTTTTGCGCTT
+
,1$,;>F96=FF:1;%+B80;%#%HB)/?!8F2?=1;+>6>6$/F)'@CA?5&&=5,"*28&54#!BCC.922"HHGEC
@r1505
NTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCANCTACATA
+
"8,D4A:2DH0F/1+"F3?=E$3648/1HA:E?<@?)F*14E>?!8C=B%@0;'-%4:C*8B)'!=2%#/<<AG5+1H#@-2/'HDA?B?$@%#)*5=09+2>#DC29$<(630+C#9<$+<F<$3H$A01F3-=$,1"?:E&%%.C2GG6?>0&87-?6($"(
@r1506
GANATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGNGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAA
+
0>>68H%,?+F8!442$)0?)9)6HD<-A4#7),F#D?!7!GE2?>HB:D.9@H?!<;&G&FBHB-2':),=$A0.5)6-%G*7(F1.*74CF&#>BB4>"&850(>%4GG+303G34DF?"636%285.(:/)(&$84F%<%,%+->1:F>114&/%F)-D8"A:
@r1507
ANANNTNGCNNANGTNANTANNNNNNTNTTTGNNAGANNCANNNGCANNCCANTNATCNGNNNNNNNAAGNTNTNNNCC
+
$#!!$##!"!##"$$$$"!$$$#$$!!!""$#!"$$!!!$#!!#$#$"!!#$"#!"""$$"!""#!!$!#!"$"""!$#
@r1508
GAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACG
+
9/@*&"&E13"",$29D$8;D8><$/++"CH9F>.!DD(B9&%7149#;0H)A&82%,+F"A8-*A!(&##C73H+5.9%5!D9?
@r1509
AGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGC
+
G8=1=28:9/)*:4.*48!+#@$'6G;&2.7='F;7643?8844$A)'?<AC2
@r1510
NGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAANAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAA
+
!=@1+F:>BF&BF0.<>1>G+1<EH&H1887'5</(?"*32=7-0)-5).+E->/!-A>3%:1-:32,--2;%/!D%C?50<@+44=GE=8D8@!$<1A3<4"3C(D%/A+<"#7=7:)A!((%$-5B%E%E5)H##,5=B
@r1511
GAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTC
+
G4-9/=:2@3;%04A"#G?,?'5,',+<%,54C,=DC2159$$(C!H#9!*E(+95$#B+H$+9"&FF'
@r1512
CTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCT
+
,6,H9'G3>2E6>D*:9@'4+7(')@1&#&8G9E8)=7@,&?*5(3A@28.'41F*G#D:&)!@&&"D2'%=14H:;</A<($8@&=(E,28)("@<"<!;5#<8;5#E=/'&.:-.<,=CB9>712E4&':1G*A9HEC+7;2AF79,3FE-<
@r1513
CGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTC
+
<AH+1E()=$<-"F3-:$?!8?:.#:"1;.D+*EH3,.,0&%*/D!;"690@H0G4=CC%B<5DAA.?F=:5$(C7;!#FB6;?=.#9
@r1514
AAGTTAATCGAACANGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACG
+
"+'&!'&'$(**'(("*"#)&&((!%!*+%*#*)($(*&$*!&')%&($%(&(!(+"*(%&**+&)%!!$!'"!!#*%+""+!!))*!!)!*#&!)&&'&&#"%!!&('!+%()(
@r1515
GGNTTTTTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGTGTTATCACGGTAATGATTANCAGCCCATGACAGGCAGACGATGATGNANATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTGATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATATTGCAATCAGGGTGTCAGCATTATGCTCGGACTGACCA
+
$)!!*#%#&+#&(&#!!!+(#*#!&#*$#*$$%(*+'%$%%)())!!%#)'$')%#)#&$('#&#*%"'+$%#%)'"#&'$&#$$#%"+***!%!!)!&)!#&"#&"%((#"*'+%"+$*)$"!%*(+*"!'++#$")%&'#$!)&)!(*$')(%#%"(#'(!"#'%&!#*!)+%&+#+'$!%))%$'))!""%$!$'(%%"('(+%%&&)(*)'$$''*+%"!&&%*&#'*!#)!)$($($##()(&&*$"*''")!#"&"')'#+%("!"$%#%$$+%+!%+#
@r1516
ATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGG
+
D43"/H3H/3*?+=&),E9"/?!6G?<9<%59F7,6-1F>0*><)<%>(7+D3BG
@r1517
TGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGT
+
=C,"-:C/'=38D6D*01/+"4$<0B=,'*<0$!0!+/!9:5'%-'A,9G'B77E@#DGB-70013)F>.>;G?04F/FF:7#(:'.E1.#65*4/5/B5G5C4">A>*?CB;"=B6.+$7E3>)$-;/'F:69+'D1">FFB(<3C%:-)!,
@r1518
NAGCNGCTTTCCCGGAATTACGCCCAGATGAGCTNCTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGC
+
#+BD?+$06B38777/'A=7)-:(-@<4G="H/88@.;H$-C1/)F"&B1D#59G;.E>:%%G7&;+9F='
@r1519
GAATCGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACANCCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCC
+
40D0B;?%@',:18<(3C1*5E$0B-HA7$&H,=8!:%E5&'*92,)/06.;)3;3.44:8/D*6G;>"7/(2??":<-*!/,3FC$7>;2--C!;#H5;C"1=F(9-0;.8!D;
@r1520
GTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTT
+
HG51,<C1$+1-'D2FGEH/B+D79BG2%:&CC'C*@:96'<1DB?9;?3098FH<G<&G3*",@?(=;7
@r1521
GTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTNCCTGAAGCGCCTGACGG
+
C:?2(C??B'("@2#F':F?2D;D38/B#F$BDC2)'$1>???$0AA(1(;=2C6D3"2C*H:E.(,8<G)>F%@9F-?/2);.37+34=(E"<3H%%:$*.G;(G30$/@A9<$7B:=-2B
@r1522
CNTTCGCGGTATCCGTACCNATTTCGGTAAGGTAAACCCCGTTTTTGTTTCTCTT
+
5-$'(>@7:C7(%GF!B-2>@0471.8@!C<;:3)"3"56?71&$@"0DA-(;+&
@r1523
CAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCT
+
1('7=8=.9&+C$<.6::#).H/H9-F!?F",E%1>/(.!BE4A?5'=A=%<,!9:(:E##'F+@<&0@A99?%$%%(A
@r1524
NCANGTGNNCTGCNANTNNCNNATNNTTTAANNNNNGNCNNGGNG
+
$##$""$!"$!$!#!#$"!""!#$"!"$$$$!!$##$$!$$$$"!
@r1525
ANAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTATTT
+
)!<;<6?2H%';7>5B34E8'1";2("G9FD66"+!F(2*0;B;C%;0'*@>H)%6<)C27#)D
@r1526
TGCTTCGTTTCGTATCACACANCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGT
+
C,1=*G>=F;+D$!DDE0=)83%C;"D46@GG1=,35*4.G/C74,=E+4D<:;$)'!*C!.7CA)(:.>!$#G!&*+2H/<B.F,50A$==4A:@+C2!62/5!EB+>#$(53B'-2G>
@r1527
CNGNCNCNAAANANGACNAACAACGATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAAT
+
($%"&%'!*')$*!'&%!'*#*%)$+'#'#!%%&!*'+#(!'%$&()($)(!!+*"))#&"$!")"++**!&)#$**&)%+"&
@r1528
TGCAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGC
+
&!$&H!?."*"$$-86!<)70'7:#:)(A3.=$!CA0#!#?,8"<
@r1529
NGGTCAANNGTNNCGGGNTCACNCTGTGGGNTTNTAAGGTGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTT
+
!%*%!*'!#%)%"("&(%"%&(!'#(&*(*+%!)%!+)"%*!"!"(%#%'+"("'&'!('#!"'#)'#**#$*$+!!
@r1530
NNNAATTNCCTGTAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGCTGAACTGATACCGGGGTTGCTGAGTCAATATATCGAAC
+
$$"#*(*!+'$"#'##"'%&#$%!(!+"*)*$'*&$)$*!%+*!#%'!+'*#%!$##%&%&'&'&!&"(('')"!"##&$*&'!%(&%&"%#&"
@r1531
GCCTGAAGAGACGTTTGGCNGANCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTNCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAG
+
@&(F5G$=D:1$*G/95>E7-H?A7#A/@F.D2(;'E%+8F-#B325(6(5?F27C'3F=5A3A3.G%#?&>FG;H@%!:*:4+(#1="C4%*D7>8)A<5*"05?@,E1;7%"0-C;58#;<=$A3-?8E@='8!!7'>&"1!-=+6(-/8@06C>8+H+<%2,@1'+0>',@,-8
@r1532
TTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCT
+
8#3/='1CA6!1)(=<(<,!7'BD,G=C'=+:2%,8?$*A,+@348EF0;?;.*+,8A>?@8AAD2;4)C2:C+6C
@r1533
TATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTG
+
A;#=/>/"50>1,&5(<F$(%8H?9'?H*E+.">'F&8;7C./G"&5:"<8,"B$!B/31)CF:!>72$-3*3;(::&9*6.B"6>+.FF8C71-%<15.+A.9A0).0)G:-23+0
@r1534
AAACAGCCGCATTATGGGGATCCTCANCTGTGAGGAGGCTCAAGGACGCGAAGAACAGGCACGCGTGC
+
<4E525<0E(5H-A:!-'""B$>+338!!1*3=#>E/F$)-=27FD9H;E*%(4$/-F':!G$>#+3%
@r1535
GTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATC
+
$F1(7EG($'B<&!2'5646H0.:9.-(=9E/2,*32&4)5
@r1536
CAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAATTTTNATT
+
?C!)(E5**(HB%;CD01%/322-8:2%A#@)F@C;F5*8D=GH2
@r1537
AGNTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGNGAAACGTGATCCTGAAGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTANGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCTTAGCCGCACTTGC
+
*&%+'')*+$!*%+&"!)$++')(()))!''#&$)!++%#+%&$%)*+'&$'#("(#'*$""%%+('!)*!#++"%'!"%$&!!'*!'))("!'%"*!*'$'*$#""$$''*''"!!($+&!*&#'%%'#&!&#*'%'+(+*+#!$(&"&")'+"&$#(%""")()!&$'#+#$#&'&("""%*$(%*("#+&"#"&""'##!$$!)!&)'$&"%"*$&))!*($"&*$*+!)'*%'"&$%*"&#'#&(+"!!&%#%!&*!)"!)+%+(!
@r1538
TCAGGTTGTTCTTTAGGAGGAGTAANAGGATCAAATGCACTA
+
#D#74!;-:*3C98B5"0)+325"..H)"$$+)2",/09:#'
@r1539
AATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGGATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACG
+
;,E*799%-40CE"21#$*$BH@HG.H;:17G(=@.?(:</>9/!AAA"C'EE6A<8.,'::><'34)99<B#!3,/?7+)D34B&31?9!5"+>90.,7!=.=G.B'+"?>3E9-::0@F,@88):;600@.5G4-$="(?&,=C1!D"!7+)3&((&E/<0E%0;9(2*453ACE0.A;&20'#@$:
@r1540
GTTGTGATCATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTAATGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATG
+
0,7="'C7G(.@/;/*#/?:*B<1./&%G0!:D409#314A0!@/(FA&F;B3(BDA922!D8:A8'#H>+./HC-G?!&D.D?97A8"8>FB3<0F."72F$/4FA:FA%$10@#.2$1(%;*
@r1541
AANNNGGGACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGT
+
'*##"$!&%(+%!&+&%'&!$*&$$$#((#+#()&(&'*&%+*))(')$+*)!"&#*!++&#"!*+%*!!"
@r1542
NGNAAAACAACAATTTTGAANGGAATGATTGGTANCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCT
+
$(!+?25F2?EG=4!46:3<&&D*(HA2H6E:).$0+1-F3#C5,'-A1+*H4*FF05*D2DH6/%&C,B$8H.H>%"-A*@+-.*.A%FD@8@;1>43@@1$*)1,0C?"5D>$!B->:..
@r1543
GCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTT
+
C>>(#;D)(H>")/B;/'89/6H*G+-??!E$"2'5*@*CE.(2>*96B-6<8G2?9(5H)*@-D40<87D7;2;
@r1544
AGAAGTGAANGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTA
+
"4;,@?((?*=!%%.,#E=70&E>5B))64)".5.C/5!7&((C304=72B#8&2=(7/!'/*".9E4BAE3/,
@r1545
GCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTNCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAA
+
G5H@/*?2,/G:;1*<,CD0+B;&!<B-HD)C+!;?7EF&0%')80!CGF/<F)4@;668>E?;9G$G=B'B$@B80/$F-4F2#D@7210=2'*-39/29*9AAHH%)A('-%551%$*G?,C$);D9F669&';E*@=%:E)+#1=;C&;HA!4#&+D92.@@?D-H!&<-!:A;$@/!6%:EE/E4B(C/-*@(#EF7&<:BB0+?=4
@r1546
TCGCACGCCGGGACCATCACCGTNTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTACGTGGTGGCACAGAGTAC
+
7#+C2?1.E9431?B(*&((*@(.=G-.0A0%!)9,BG0+5>,C/D=22*>A%++!))(!$:'E8A5)D'19'$/.E+@.<F8F?$D'.GG<4<H$:F5'+.#<-.=>3.64&,(2?9#A0:5959=!5&58=E@@0(:0@>%D0*+;E(;),'$//(F=-D#-
@r1547
NANCTCNNNGGNNTCGNNNATANANCGGNTTNNNCACNNNNTGNAGGNGAAGNAANNCCGANCANTCGNCCCGCNNCAAGTCAATANNNTNNNNGGGGGNNNCNGCNTNCCCNNGCTGGCA
+
##!!$$!!###$!""$"#!$!$!$#!$!!#$"!#!$$$$!$$!!""!!"#!"!#!#""!"!"""##$$"!#!"#$!""$""$#$!$!!$!!!$#$#"#"!"""$!"#"!#!$!#"#!$#!$
@r1548
GTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGNGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACTCNCAGAAAAACAA
+
HA>)><#A%+(2C1#AE(7'2$<>++)<'=%'0!)C8GG)BF/$-+E:C?D;7!41>29D;<-F&4ED>A"*A)#=1,C$1<=$G16$.A0A5.+@G!4*33F.BD"B66<HH;&
@r1549
CAGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCG
+
'!1<*C!HF0;:(2:.5$>*@'F??;!5%-FE&@F)173<;(93DF.2'('/<<)1D@?E*)90?1$A>%G1@5?,6-+D+,108;=B">8HECH#AFDH'BE19%.!%->7"?!0;4,9>C-FG;G+!$)>F=7;8CD9-'/9C4C.(,D89
@r1550
CGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATGAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGG
+
<B@B:G6F?;1H?4HA33,)+C42G*>&F4G%,%1%@9!7"<?05H;=FC5/<'#>*"+-+!<BC)80<.C,0!1'<G,1'B30+2D,3*>5$=%?9;@#F:-%F)<"<&/21+H&84)!0#-<CBBA&49>9>';034)';"8+1E*!E;"1*@9
@r1551
NCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATNACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACNTCTCACCGAGCGAGGTGTTTACGAAGGTTTTACGTTTTCCCNTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACG
+
!GF=21'38CA9GF4*4!5-C76%-."9!-!4>(H$EF99.7%#'BFC=*H&<A=$:.G-,A'0*)HB=83BG!(+1@+:F<GD9#3&+/H)'<+@2"6!.A#6:%?D1:".(2.)'80?@;+!E$E*6,<+8+/!)(5/!"77@14##C:">+,@2&>29GAC3EE?C,,0*;E1F(C=.=9G*G!;':9"#-';0<'/.H.5B>FAA*#%#30&8#E@#:HE?>)!GF6?0!%?2B98'3))
@r1552
NNTAATGTNGNNTNATNNGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATG
+
$"!(()"($"!"%"&"&'%(+'("&%)"%'!#)'+(%$#"(%$&&*'%()*(*''''
@r1553
TGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCNCGGCTGCTTTGTTCATGGC
+
:=8<:D)/#@+3;E#=E*D;%2(?@(0,/!%&'GD;/(>6!<;86-A;4+7":*@=4);,>$F?1
@r1554
GATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCAC
+
(''*E/9=>GBA"03=&0',)=GD>,4D13$:<.8)12@$C-;;#;%2>6"A.5A>E1,
@r1555
NTGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACNGCCGGTATCGACTCCCAGCNGGACNGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCNGATTGACCGGCAGATTNTTATGGGC
+
&+&*%+&#!(%!"*'"#!$"(!*+)&%**#$#+!)$++&)(%"+))%%"&&$&%#$"(&###%%*&$+&*)#!%$('+&#)"))&"$$&&##((%)"*&*+%*#(!!!+#%$$"*+!((+'*++#''+&**$**(!"!!$$$&$)(!'+('#"!&!")'*&$!'#(%+'%
@r1556
CATGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTG
+
=CGDE804+8.:0B@E+HE28.:*,G?8:#-%:;/G4B35#?C>:,3
@r1557
TNATGCGGAGAGATGGGTAAGCACAACCAAAANAGCCAGTGATTCTGCAT
+
%"4-4<?G@=&;D!D<)5@=D*!E@C.H2G5).):C'!'%!<60@!'+>!
@r1558
CACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTG
+
4'6-*4E#CCD;8%7*$@>)5$7':B8A/689*@)(>:1(?2GC&(!6$-#)H=#B'62E&40**9#;B5'"5D,"=#!4'('?1E55CD&F?;,9
@r1559
GCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACATCCGCCATCATCCNGCGAAACCCGATCTACCCAGAAATTTTCCTCACC
+
E9@E+)%)'>GG?4C$<E3C7,$*;@A">H7;=1A-<AG1"B0>/G7-93D5"$)>B-/G&/8'9!C0@%69>="*B.=7/A53F?6B=3!=1<&)C>*
@r1560
AANATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATNCATTACCTGGGGACGCATAATAGCTTCTGTGGGCCGGACGTTGCC
+
$($'+*&#&(+%!!(#)!+*%$)#(+&(+''%)+$+"#%')&$$")(+)$*!&!**$*&$+#%%+%(&*$%*%&'%!#*(%&'+)+&+#)!'+"$#$$$+$##(%#+#+)++(+$)&)'%!$*%!!$)"))%&*(&+%(
@r1561
CGCCCCCTGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTAT
+
,E#,2B"'1,B>&&+-$9D9BGH$2DE)(9F$0(1+6%;*$(;7D!69$D1@EE!05B$EA@F>5C7%?160",;;<?!73E*<,EE9F"3"8H:*,C!H2#"GG"=A4.D*.)>+;A?*02?3A(5;.E#G$&345"%&#4+;/$3&H2"1"5=D3(4D*-:6$3$"G<$*(F.9=C<3=A4/E@,A;)&!?B'5*367444CC:$8!H1B(C$"=
@r1562
CGGATTGCCGCACCGGCAGCACCGTCGNGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCNGCATN
+
B6'C>C/);*C9/-$3*%$<H/&BG%:9/1-.92-F+.C,1G<DC70<EH$,@>F2$G2E.*(;/C/01A-B*5G1
@r1563
NTAAATANAAANCAGTGAGANGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCT
+
")!&#'&"%'%"))+%(")"&'+++!'#!'$'%*!'%(%"#*'!&(!)+##$+)'+&
@r1564
TACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCA
+
H9B+(5-D/9(#9/,?3":<49F18%=;.8:%)&F(10/=><.(A;$0%0ABA"1??8:37043+,7AG?;<F(>121?%,C*08082(
@r1565
GAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGNGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAG
+
-$7;45$7>06*><+C7=.>#23+&??'.&E@D:4#F<!?75+3+=-0,9+)&1%#6'$D7E(=?CDA&2E5-/*E<=%&*738'.
@r1566
TGNGACTGGATAGGCTCCGGTCGTATGGCCANCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTG
+
&%#+!*#!%'++'#)%&&'*&*$*")#'*"%)"#!(+"$#&+&&'%!%+#"$&'+))'!($&$#*&!!)!($"#!(!(!#!**%
@r1567
ANTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCA
+
"&.+G8*,'"G*6G*B-.6?8%8@/B!1$%=65*4E%F>+!$H.#74G3B:*<)3<*3
@r1568
CGGTATGGTCACCNGGCTGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTNTGGATGCCGTGAAC
+
28@!77>0$>&(6C1"-G-:6C@9&$*>:F*<)G)H&2%EFDH7?.@$E9A<CD(G*@%.=)(;*C47&(.6B)("F6:>;;3.6G+*&AFD9ADG)
@r1569
NTCACTTTTACCTTCACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGCNGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCAC
+
"6<>>G&A!/!4H+)2B)163<2.4(GAA-52(5.(<.54A@2,@1%=@:!.7H(@;9*(($!>"!#,,88-1D=1"="%/D+'"07##"C$6A=-?,$1?;H!>H@H!.&7&EG=7H"#2"
@r1570
CAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGAC
+
=/'B-"E55A;*4E<G/6@"(?;A7$%%'/AD(3/,.2F#</DA&=!'31GD5C$DB$6("4G0C6C.45$;#,EF9?F*,7>A/0,&>BB12<"/&&0@EE;+,#15;-@.%!6/8*@;%FFCDC6C
@r1571
GGTGTTTACANAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTT
+
45!+=8H'&4?*G@F9<D#H2&"H&9=/>3!H!=?%?#E1.C36,0@>C("614D2+B4F"B0=F@2$$08387@A+1
@r1572
ANCGTCGGCNANGNNCCCGGTTTCACTTGAAAATAGCCCACCGGAAACGTACCATGTCC
+
*#()#)&*))("&!#)+'#('%*)+""!%$#($+"$#$&+&!)')&(!&'##($")+!(
@r1573
AGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTANGAAAAACATCGCCGCACAGNTGGTTAACTTTGACCGTGAGGAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCANATCATCAACA
+
,%*7-9<&#D-(.&C%1F59F4:D.)9@7)&ACC;<$@5;35*@/1-;G1/3#&%@(E@A>&1>%?0>%1/.*,G!B;3F(4*@EC8$:"+7354#22,6-896",(?953E((;2+H8$:D??)-99/5%7;"7%">9"2CD,/>=)D"BD(@-9/HD?!%!'C-8#0C,G<FF8<?#&2=0?/$$2=C("7-+06?B#
@r1574
ATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCNCGACTCCGCTGGCGCACATCGCCGGG
+
A1$'H=-4"35E.A/E6)0:H8E*.D,>*9=+."!HFE33@@,7%&<-";@C,%F7%5(0/&,
@r1575
GCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTT
+
,8,'5E-3714G75@51?-!A>E2/5-=E:,<.;;E"8>>.6+H2
@r1576
ATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGC
+
$62;!%&08">@.@%-*,*+,D)E43E%2!83!"B1F3>C;%7?EE/0)#E$1E95#>"+B;2FC'==BF.321)1C)<F3E3+,43A+?2B2G130C>#568?+=%+?'HD$
@r1577
TNTGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGNTCTCAGTAAATAGTAATGAATTANCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTC
+
&(/49:",++B(C.>0F+D/+55#HH#01H?"39"4+2$<1%;@9$A:D=,4*04C,1E"'0@B*09;C*<4318#DD>"EE(@?<<,'/GH:H),6;8@*1C/G:>:A&FC#:#652./=6/F)6!)'.48">DE30A.8-=+(>)6*<9-E>%?165G+:+
@r1578
CATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAGCGCCGGGACCTGTGAGGCC
+
0-;-,@-!@,1#D&87C6C44DA6>&D6<:B(=H56!,D;1*)35%G&;.2=.FE3'++!C=F9!2D6CD<1/2C?E@,C:':HF;5>F6;*F0?)G#B9+&(C$=0
@r1579
GATGCCGTTAATATGTTGCCATCCGTGGCAATCATNCTNCTAACGTGTGACNGCATTCA
+
+!+"&#+&%'*#'''!"+&"&&$%#)&*("#((*$%*$&#&*#")+!#'+!(*%+*+')
@r1580
GCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAA
+
%20-/6%,=G9C913C13BF$AD,!:4-<'41&(/":0'D/$7(!H?!GE*>*2"0D-F:/5A(E;6=G)H!9"-0!:AD.1'B&03(.D'.@!/C+A&A#//.16-:3DA)!?-0,E#%;2*612!
@r1581
GAATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCACGTATCTGCTGGAGATACTGGCGGGATTGACCCGA
+
'$7,.$&576G3DC(5'0($A614B>92D9.@@-/:+?C@3*H(.D+9"G@0C-&G<+%;7**5"8!*/2"=850>@B.A0*2'&=7AH+.%0
@r1582
GNGTTNTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCANCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGNAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGTTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGGTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGNTAAGTGGAATGCCATGTGGGCTGNCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATG
+
'%())$(%+#("%+*"*%*(%!%(!$!!(*!)(&%&*(()$!)#++$!(*(&!%&")")"'"(*%)*+&$'+%'#()%!'#$"))#%%$#&+)%()$$$(%"'%'+""'*#$(*+""*(!)"%!+*)"#'*#!&!')#)!%%%&!((*!*"))*!#)+'%()*"'$$*+#&*!'+('$'($#$+#++%'#$*""&*"&*'#+(&'$$!+&&(%$)*'%+!)#!''+%###(&$*%*&'+($)&(+!*&')(*&'+(%'!)#)*"%%%#"&+'&"""*'"$*$"'%*+%&%'&$(**+'$)#"&%'"#+%'#')$"#&++$(#'+(##%(%%""*$'%+$*!%*!(%$&!!$"+#)$"#"&%(%$!&!((&!%&(%(#+'&$("'*%*$*#"#"'"%"")&"&&+"#!)&
@r1583
NNACNNCANAGTGNNCCGCNGCCATNNNCGCNANCNNNATNNNCATNNNNNNNNCGGNNATNNCANCNANNATGGNACNNNNCNN
+
"!$!!""$!###"$#!##"!$"""!!!"$"#!"!$""$"$$$!##$!!!""!"!"#!$$"#!!#"!"!"!!"##$!$$#""$$!#
@r1584
CTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGCTCGGCCTC
+
6>6HG?%B"<,@)F=-&"F?/,%($*+F0AHG:$="#=*0)<G4'7G+$&1D!/5%@F6(5<79>!2+,BBC,%<
@r1585
GCTGTGNANCAGGGGTATGTGATTAATTCCAGGCATTAAACGTTCTCTGCACCACGANCAACCAAATCGCCNACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCNAATCGTA
+
**'"*"'"#+%$*+((!*%"%&('''#((!!+%#"%)'$#&!"%"$(!!%''((#)&%$%'(#!!$'$(**&*%)#!!!#&*%#%"'%!"&&&'$'*&'''!+'$+'*&')#(+
@r1586
NATGAACGACGTGTTCCTGAAGCGNCTGACGGCCCCCACCA
+
&E6;=?HD1>.8E209$(C9<;7E0;@!D%6-C:.&HE'2"
@r1587
CCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATA
+
(.&0@%"9'557&('0">F83D3,*5;:@H)*B'"A"&*5
@r1588
GCNCTGNATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAANCT
+
#)!(''!+'"!(!"+'"+&*)(+#"#*&&"&#!&%&"!'(#'#(*((&!+!)(%'$()$$&(!("*%&'$"
@r1589
CGTCCGGCACTGACTGGTCGCAGTACTNGCCGATGACATACGGCGCCCATTTATCCACATCNGCCGCACCAAGACGTTTCCCCATGCCGTAGCG
+
+BC":B(.-7A:B#@,B"+=5).;HD8F+<4&%<1<EF3F3.4C%3';B./5GF,"/C30*<C#GF5D9<8<,874*#%EF%EA55126H%>5(
@r1590
TCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGAAGAATANGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATG
+
@0:&974,*%%."=.*%14+02,B.%1@B;$F1>2*1:H+EG@<H(6/A'2!(,'?.=19BD.=@F=6:2H"3;)?&F:AF>+*#B@G,3;>'88&2+H1EB&%'7.B?8)4.$."F*&ED*+D
@r1591
CGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAA
+
D7@##!H?3,%7D@)+BH0/@!6E,%8DE5*/""-5&090:#$'E-3;&<?:5E5A8@#3><(46D/&D-D1:--7)=4%.A
@r1592
TTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATNTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACNAACGCCATCGACTTACGGGNGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCT
+
F.*@1)99$:?%/>"+53GC'/E0-!.=H@0)/.1$@8+':4>8/E/)BE<4/%#(;1'=$.C-$66B757+9>"*7?"2H5C.#37F@3"0%4!%!';2$84#80-E'B@6&=E"F.54>(9%*.$5+<A=3;>(A%>-$*+$B>="E<0,613F0$5#=>;8,H88$A3#/+D;+"E'4=29<4<A4+!>.C-%=GG4%+9B(:/C;(8E>0;G@E')(G6><G#7.-1*7'#H;1!?")%!G+GC?,'8A>*$!43$#?626<B5H9@%B407$5D""G7+D>208+#&D2(@8!.1.,%,HG5;G*3;+-+#9/@)8#;<E2*4.8G,-81BBA77!#C((3'.)'!?+D*&B-D$41A4H!6<9B@'"HD)A=:H$/(!>D,D#;BE8BA48>8&:B()/6
@r1593
TTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCNCATAAAGTACGCCCACGACTCGTTCGCACTGGCNGGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCNCGGCACCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTG
+
,9D5B?5%9,>?E=9D?;H066"-?5<.(?#.10B2<&D%B>#&#:5&'+>/AFCF/C#-3C7E*=:EG,>AH9#%(.$!+A,5""/B"3EH"((*'>%C"),H!=++-;G6A&8H:C%'@3(E(DF8(A"+6>)<;;.6/+.';@:2BCABE6>/>$G(=50'><6G(.=4%'$#GA%=-996HC:/$3!F;;G3C(D%&2.C=871@%>.9CAAG,?
@r1594
ATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATTGGCATTCGTGGAGGCCGTCGGTCGGGCGNGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGG
+
303;&5AG19/A*./7:A2*9?A9=E#E#F9,CD-07+G?0D+%0+,(F;G"F4&%%%*-20D';FH4#(;2*?0=@A0=E<8+=ACGGF>3/,3,&/-!4*&<4.+86@*C8>8+:,1;4<(+0$+5?-2F@:H5
@r1595
TGNGNGTTATCAATGTTGTGCAGATCCGGTGTTTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGA
+
'*"(%*+(&$%''!$!!(%+$*&"(")&(*##(%%'%*($((+$'*&"%+!(%$!'#')&*%)'"+)&+$*!)"
@r1596
TCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAG
+
@.8>A:.)5(3G"F4!HE/#<%?%?//&9?D6F>&-D/F,-++97B21?7**!:<&&0G,+HC?:8?F/"4C3(;AFC/<+:%%-"+%'93)"((F6,G3!
@r1597
TTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCG
+
(G&0AF0,3+<D%305=1>GB"#D/F/!>-)F&,05/6+&3/C&G##:2F@6#*0*8B)/"
@r1598
TTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCC
+
#7**@%#"%&0"856420;D7%9)0*",$*-#?4H1/0/52G%</B=.H;8./E#5<:6H($64F.E;CD(@1)D
@r1599
CNTGTNGTCTCNACNCCNTTGATTNTTATNAATNGTNCTGNNCGANAG
+
%!'%"#$&#")$')#)$&%%)&%%!)'(""''&"'')#(#!"'!$(!+
@r1600
TCGCCCTCACACTGGAGGNCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGNCCACTATCAGGCAGCTNTGTTGTTCTGGTTACCA
+
E9G5D-5D"1-*=/67!1*364>C"6'849H!(%$,?/:*0:&!.-FA&7B!/F"%&*2CGG2?9)##':+%!3D.)*2525.GB@$)B%2F6-%H,(,:B8+'2C9'@:$08+;"E%C+"C'"1$63A<"<(00@?#,C'/):)6(7;:F&/(A58+A'&0,F";9?:5.&++41%6/H(&<(
@r1601
GCTGNTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTG
+
$==G5&>;EB/FG4GG:B;A$17E10!.CH)3%0).H2-539*?@-
@r1602
TNNCNTTNNNTCNANGNNGNANNNTNNANTCNAGNGGANGCNANCCNNGTNNNCT
+
$!$#""!$!!!"!$!"!!$!#"##$!##"$"!$"!$$$!"##!#!$"!"#!"#$$
@r1603
NGNATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACAACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGA
+
'A%FE@2B(*!)7,*<?9*0.587D1-#;?8B61&42C%5?&,DH:7<.@;F75#!35D*+F;6AF/8E,4<>:570-.:*G@/.H!$:<9A?#,9692FH9E+2==00C!;?>;
@r1604
TGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAA
+
?H9CF#6"*@/@5$2+CE$:5"-7;6F934@-C?BH/F1AB&<3B7.>(
@r1605
GACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCA
+
G<!G1!C>);<>?B$:4%#0,H,$:D:/#FC6>(0;F(7$,>9"=D;)E6-<0<?*E!?&B=09;%F-!H(E/"=9/1C5!:H*F#*H;7
@r1606
NGTANCGNNNCTGTTANCTCGTACCCTGTCCTGATACAGGGCNTGATAATCATTTTCTGAATACATTTTCGCNATACCGTCCAGCGACNTGNTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTC
+
()$)#$$!!!*)%)*$#)%+%&%)'#!%$$$""'&(%%"!(&'*$)'+$+*!*&#(())(+!'%+'"!%$%((%'#&(+(+'*+%%''++$$%'*+&)))$&%)%+(*+!'$)'!(#%'*"))&#%&($(")+!'
@r1607
AACTNCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAATCCAGGAGA
+
:4@.-2#;C7@%9/0H@@F<CF$@#+%-5<@07+(C):+#+";H80$0'5DH<,'@0:4<#<.B$45=+@9A10"G+/6%=A40C2*+5";24E=$F7F
@r1608
CGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTG
+
8GC,E.#?<,8+"E$76<84('8+7,@36*7>%H*(<;E!,+'-
@r1609
TAATGTGTGTATCGCCGGCTGTCTTTGCCGCACTTGCGGTGA
+
<F?D(,343H#%&=+47,;77E(@C0!"8-."5?;<))6AE!
@r1610
CTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGC
+
,<!>,>>'B%G+2(D%=!(=!#+@0!":7.11?#9<@/8;G&&5#H4#7<,)F@GG@('=-8
@r1611
GGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGA
+
.;20=6)&%%,09+!>2A5"$>!F7,B=@H.2,&,2D9H'1EFC4'296B:6/
@r1612
NANANGGTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGAC
+
&(&*"&%'+**(($)+%)+'$&$"*%%+*)*!)!*$!!"%"&)"')!#%$(!)+")$"$
@r1613
ACGGGCAGACTTCACCACATTNACCTCACGGATGTAGTCGCTGCCCATCGC
+
H:1;E=(5E#/-6!(<;?HFH,&&4'#(A$>&/78<CC@?##":%?5:4@'
@r1614
CGCGTATGGGGATGGGGGCCGNGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGC
+
)1:!<E?H(8*B?"'25'"'%%E!&3+:2BG"-:/>9<A0=+C;&#/6F013)*?4%0;HC&A
@r1615
AAGGTNAGACGTTGTGACGTTTTAGTTCAGAATAAAACAA
+
"(!'((++$"(('"%)!$+!%'&%+((!*("")'!!(#$&
@r1616
NTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCT
+
6="B7-4?;81EGG6:F?92-0+9'44;&<!#($#C<349<,&HE'493F
@r1617
GAACCTTTACCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTG
+
B3C?:/2@&%3!D,HAD4*%2<*'F4D>7D5AG"<F-=7AD&7$,(&7GD@A9&/&H#H<.H?0*.?5>4#<6<C06&@/-!
@r1618
AATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTNATTTAGTTCCATCGTGCCCCGACTGCAATATGGGAGAGAAAGGT
+
)#(2G41?$,":G%(&&%,<2#8EG*>$@1*'-95.%";9@86.&F.9@!B>#>)G'F)&F%<2A9*0.2,5360D-)-"6<:D8C%D!?'<)#*CF22A6=
@r1619
GGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGT
+
E3&B-=9A<"D%)@2%A<;@1*!1'1!#&-$&,83<3?)G.$5E(4)>@:$#@F8@7FGH0&'5,6@$0F-8599<D*<1">0:)%7D#E2#%.(92)(E/70&BEE*"
@r1620
CCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCNCTGCTGGCGAA
+
>?F5G9F*H%**0;@0,>%A!&+$>">9A,$<30#$#G&'G0))5@$D/B7&F2F;6'==A;<)1F)!;6'&&87.<8!HC&5#999H#1DG357-
@r1621
GTTCATTATCATCGCNTTTAAAACGNTTCGACCTTCTNATCCTA
+
?C335B!H--GB"*+"C37!:A(<;CCE'.<4A:<.<H.@.6")
@r1622
GANNTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTC
+
%""!(+"!!%%$%*!(#+"#(#&#(*($+"!"()**#&''#(%&#$$
@r1623
GAAATCGTCTTTGCCCTCCAGTGTGAGGGCGNTTTTTTATCTGTGAGGATATGAACAGA
+
#$***)!*+''#!*+($*#%!)$'!#+$($"(#(%"&(%!%&"#*)$'*"!%***#**(
@r1624
GATCCTGCAGGNNGANGNTGNANCNGTAANCAACAAGAAAACACTGGCAG
+
*((!''$*)!*#)')%'"*("##$#(!+($#+$+()+%"%'+%#$''%&$
@r1625
NTTAGNGANTTATNATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTA
+
#''!%$)$))'&)(*+#")$)+)&&+'"%"##"&$'#+'!*!$$)#&)!++'$%!"#%*)%+#+(+"&$*%(**+%$*&$($!$%+(*(**&'*#)!(#'%)!#'+"##$"(%#%)'#)+#!%"+!&&&&)!+'!)!*##(*)*&%%)(*$(#(%$('&&($"+*%$(#($&#)&%"%(+%$*!!"+(''(
@r1626
TACCAGGGAAGAGCGGGAAGGAAAGATGAGCACGAACCTGGTTTTTTAGGNGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACANTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTNTATTTGGGGGAGAGG
+
)+!&!&'#$*)!(!&)(&"*%%%(!#*%%(*"+*%$)%((*!%)!++&*$((+'&!#&%)&+&')$"!!)*+#+)(%+(+++#+(&+((%$)'&*$#'(+"#'&'!($"&%!&&&&%+"(%$#(!(!+)$&+"'(#%$'%'+"!#$!#*")!"!%+)#&")""))"*!(*!"(+*+
@r1627
CAAAATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCA
+
&&'.GA13,224261C1.:+DG$),":$""+E?H<<41');5H)D6)"";B4(CF+9'C7'&/!D0;,H,G#C!5
@r1628
ATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTCACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGGATATTATCTGTGGCTAGATAGTAAANATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGAACTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACT
+
6E$0(5G->(*0-;@86#@/+(>?2=3$;=864+#F2=>,"!6)9A3(221>9:"9-0<7#(<:$@6B+E/!@B)$D5(*A<B&0=%1CD2,,353&&-E&=(4G4A'@9=<&/F<)=D46F1);25-F*/)%*"*!B2$A9C40@&B$5AD!$79#7,!)BAF'D/G,14;.EC:=G)26>E%8(5/*9"4>5G?6*!3F55?,C$7$D7,:7"107+:2:'*E=/=-9)0#@+(=G78F932@$"H$@3E3"#>"4$)C9#':,#>EC<6"1#+6(-A3+&.6!:41&C!A,+;0;)&23<0+)2%'*/.5+E.*$1-)+;!884&8$?+>E7&38G=#%8?-@47)$5&-)E%;#D!A/1)=9
@r1629
NGTNANCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACTCGATGTGGTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATNACCCGCANGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCA
+
"*&"'#%$$!"&#+*+"&#+()((!+#'+%&('$(%!$($$$)"&)!+!!"**"*$$'*%##*'('!*('$!*"+$')%%(&)+#+#*)$%"%#$$$("$&+)()+!)($'*!)("(+)"*&'#*)&""$'*%%%")*'!)$$+(*$$)*!$*&$&%)**'*"*#)"!$&$"
@r1630
CTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGT
+
34,:@5@,3D?C2+91<F-#90);'#(-7DA:)0(+3E#"#4+F3;:@-$'4=C:!;*6A+@@B)1+G&.:A,!/!>$9.F2'72<%+%.()@""0BE?+8'<8/8A
@r1631
GCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTT
+
3BC?,27E3F)#+(.D*;@,&9($9G;7+H,BC:',/CDD.#+1%H7-":B9(>.8#8%9)781)!%2=?18C4G,H%96<G!3CHA&)!)..E:5@4
@r1632
CCTTTCGNAATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAANACAGTTC
+
"#')(%!!$%+#+''&*'#(*"!&$#*('$*$!)(*)("*+"$!**"*#+*+%"&
@r1633
TCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTNTACGTTCACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGC
+
FD>0:/%6-=C7/=8)877$C(;926:64*@8E)$47/)A6*-,G08C=F7.*%H&EE!#;H-8:-)@&DF;.$B4438,(9"/144F.1A1B9$H3:+19%51/=#*HEG'7C#11>7!BB"'5,AB2!
@r1634
TCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACT
+
E9@5(72GF*";&HA22('6$DF8;5F=GF(A)>195;3$G=089'";:'2=
@r1635
CTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACNCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGNGGTGTGTGATACCAAACGAAGCATTGGCCGTAAGTGCG
+
21'%-7$%C*$;F*%E*!8D>G&4B9@@-.45)19<@53<C433B1377>5H3::)#+A,(9</0;<6.7:1/554,G0G1;,87='4C-C9542,>;C8=7@&)"$;/9-B%0HF77F);.>>A+5/-"''1<
@r1636
NATGGNNATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCNTG
+
"''))$#+($!(!"'%"+(#"+'("%)")!"$&#%$!&'!%!""**!"(&!(('$
@r1637
GGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACNACTCTAATTTTAATACA
+
D:54CC@=-67')+;<)D>7@#5+BG+!AC%75A-G+A&$85="+2FA!6()DF5?B;!.!1/()H
@r1638
AAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTAC
+
DA>&,$-(.><E7$6=5"3#/,;:!5#3,5,1-B?H&"1BH@#,'5%EAA895H<2HB3"
@r1639
CCGTGAAGAGATAGAGGCAGAACTGGCAGACGACATGGAAAAA
+
-0"5:5.F4#C"0*DF7EC"4$">G+:;?!81:?!+934)=+0
@r1640
TCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGNGTTTT
+
8H%6>?EA+$,<=<=*>(:6/72>0?;=911'55/E*2<'8&D&"+:F@1&@.D&1=47DBF1.8<A8('-C5&9C+&.%(!!73!@B&@#?:(H'&&;?<!5;#0.
@r1641
NNGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTANTTCTATGCCNAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTNTCTCTGAAAATAATAGACTTATCGAGTCAAGCATCNCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCG
+
!#A$84!C4'@38'<G68H!%).>)&D(#2A55E0#/H>@F7)$H/G'@->4/,)-0>7625B!26DF?.6'6-A35:;'=:'2;0*@#:4AC8BD&7G&)8H0F@?&:BG'&H<6@<(0:--38(4H2"5HE*05-6+)C'8!%"@B=CE8:2+A**#.A*93#&H6?G<C%H1;A>1EG;&+!%-7A8CH9"'HE=272#C86+<68,9(F<.H6$1+#%EH8:G4">F6985
@r1642
CGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGAC
+
1=7F1;A&*AG;3.)"9$2!"GC0H0*)0A@D%G;/F2,'3>7;<C2(81"0?G@8
@r1643
CCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAG
+
>5('1:7-);E""FA!5C6.*-B'6G4,(+?H(6*B41A=;<H,@3@>G30!*;=>(@H
@r1644
TGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGNCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAAT
+
,2-,&7G000!@B%(/;CFGD+(0EE!B.(,-)@9H!B;AA='1#C?515=D0+<:DEH#FA73@2F@FGE;/1@C
@r1645
NTNCTANTGCCCATTTGTCGACATNTTTCCCATCNTCCATTACAGGAAAC
+
$'"$)+!!)(#+')$#!#"+%%+(($'%(!&$'$*')#!$)%'&%+')&(
@r1646
GGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTAT
+
?<;AG:,4-+5G0.@01!-'552+-26GG/,896C=#,>;?F%8
@r1647
GCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCNTCTCTGTTCATTATCATCGCT
+
7F''!%15/()2+0D7(B;1+):3D*@:35"7$'A%7'(99G?C>1H:"5H,0C"#-8&
@r1648
CCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATA
+
H95/GB>+(5./(H&@&>E,:169@<F4*H3(>++$1=*,'?E-8)A,>(0#(9;".::E-,@"A2%F,H?B*!EH9:'@FE@/8C?,")#:<8A)&0C@-'/4:).@9%6,85,&H!;,HE$-=;)D7!!.2"+4"6=%!?-(!8:0D"52<>+;<;-
@r1649
TTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAANTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGNATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGNGACATTCGGTGAGAACTTAGGTGTTTNAACTGGTGAGGTGTTTTTACTTGAAG
+
8GG1C0<1&3"-88&?*5HD540;%7A)3#)5+*;8!&"28&D>73?#!=,@&B!36"F75$:9<2.4H$$7?0&A91H-17?G+(+<,!:&!+:@H:9:F$;<.@'.<*$9?1'?=<?5#=+=%:42"G!;@BE)+B5HD9<##D78D!:20>=12!+!:.G<;B8F>:;5(&>$:D@:1>@?A4)/2@"!(E3::EA.$&H>9F5,-9-@#2F=2@3*)GA?%G0C&.-41',"0
@r1650
CTCTCGCTTTCCACTCCNGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGT
+
4'/!)'E$&,H9-G3?%-)6./A"6-C..'%,&#:1/#AF2;,G&"35"4#,4'1D8#(D5
@r1651
ANCNGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCAGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGNGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAA
+
/)*=4)5/H(:@#.)4A)58@=.!@"7@D&H%B44E=+&+(C;=7B$*90#!(!@B,1'=#>>0>D20*(!@&50.(A"4%@64;FE#5'2%$,'%7-E6<EG$8@#@&.?B2A3=$E<8;/&).9@B?)+90!091!*.;1C+4)%8#+2D4?2!($>53$08DC5,<!4!?/;%:+@4//!4-;H>">=
@r1652
NTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAAACCA
+
&C#&@03%G#H/@<5)8/E%?GG5)'$4A$;<B+8F)H9';4.'%$?
@r1653
CACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTG
+
44,+;;>"%!$"/'B0BCHG$*2*!$B'>G1F&,$=(>?AFBF5&@;G8."&7C$;HBH>9>06*6';008@='*A;,+0(<
@r1654
ACCGGTNCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACNGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCAT
+
H,@.17:80&/2;8=E%88287C6C7)A@;:GE0@56H?'+&*42F9DG0)1$F?8,ED<=:$D7/98B"G=%84$3&"19F4:?1:&""%7=D:#>-$&B2)=2,"B'HGBA:/@G2*%'<13:$$#3!?:20H?:2A469>=&65#E:<:5G?5>0'."4!-%=6>#71&?2@)0%D8
@r1655
CCGCAGAGTGGATGTTTGACATGGTGAAGACTATNGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTG
+
GHCC.17C?)G";"E&$%2/EH-7H#25$8'CA>:>F=E-.72%.D@<'A<5+H9C7C084!:B(H5G-2&3E8@E=,00>7;0&'1">77BH-<C&7@;0*"/,9GF('0:;5,&6G=1@D(;"B-)0.720H*%:9&%?GG=4B,HD3B$@/;/%-72D8#)5'@.#.A.<A"41!,>7@D<7#BH,C!32''$@&:;"64E8+5?--':1@H$BE(CF#57*:"CB<92,E6C6%-6,/C&F.<E
@r1656
NAGAGGTAAAATAGTCAACANGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACAC
+
'C26,A;H*;=H>(*%D(!=<;'B(@AG9-$3@93C1A7!B7B*0&/5DG%7H471979.-2D#C4.+=>H&G"6+E4-,4:>3!:7E@$5DE
@r1657
NTGNCNTTCTCGNTATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGA
+
!#%!'%(#'+)!!(&&!*%%%'#++)(%#$""%*+#!)')$+)$$&)*&&$*$'$*+*#"*$+&$!*#$'#!*''#(+'$+%%)'')''&$++#)+
@r1658
ATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGTCCGCAGATGAGCTTGTCCATATGACTGCGAG
+
,1H.,G-3"+-2892$1D#B5>/:!B)?2&2"C:/)2*4,6#E3>D/!8(+GC8%&<!40.$06#(FB@&C78D&-,-A@G2H=:9=>"8;(G+,",#5?;3A79D4;5:&G?!C;:8":1@28-7G$$#5EB0;:$F?4F,A%86<$H57%>1)1&E:F+-=@>=3&F=)6B6<-,>)?;
@r1659
CCAGAGAAGCACAGAGCCTCGCAATCCAGNGCAAAGCTTTGTGTGCCACCCACTACGNCCTGCAGAACCAGTAAGAAGATAGCA
+
+%A70HBG'+<%<">$/=EG9-%"D)H$$>=;&+-)G.H-(.6B)/?7H:;,,3HD"B@)%F6&37;'++%ED(<=!E1'3?->
@r1660
TTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGNGA
+
CG4>@7+'%(<(2B.804,-/A:8/"8:3.=$66&3-@60G&
@r1661
GGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCCGCAGGGCTCACGTTTAACCAGACCNGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGAACGCGGTGNGGCTCAGATTGC
+
09(-*0557G"/*H'>>+HF22<!C,E>!&"%G8/1=EE:7EH,<8E$,67$=@G1F6B5"@$<-#5H$6=620=8+F3&;C3<?>*+<*>7")1$&A!D,!D3$"2:4("CG82G57.0
@r1662
NATCAGTAAGCGCATTGGCCCGCATGTTCTGTTACAGGTTGNTAACCAGCCAGTAGTGCCCGTTTGAT
+
+<1'..2/;=5-6?A-0"09B%7)9&B*&C7%%B@53$!D<+6-2$6C&9A-D52)H(B-<-21&6:(
@r1663
TCCTCCTGCGATCCCTTCTGATANTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTGAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATC
+
-7)1*=5;079-*(H)*5;7B$F5DE!@@11D97F!%2&9@71D97;(G4E%")"+3-$-D>797)3051*/D48*#D$?H&920:($AHB@G8"HC;!%,<'!EH#''=.H)E>>9=>536$5+C.&:/>D3A%6*@"6C5H5'DC5(<7;*#?A,>G*+:(,/1/&##7=6C-6D-A&E:!?>:!;@&F0!'<;<#;(C?!683%F)@$DF3+%05%
@r1664
AGTGTGTNACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGAC
+
.!9$!,H&"?@8$7,;!7>?,+D.<3!F+;).1?2F-#6"#'C+.%57B03G*1/@-?4%'-D'&0%A"+A:CH3>%2-F=?55&#0<,9&>4B<0=$F5-#G904E,?4$/!32'35#H;B+F56'(!+/.!G#5E.)01$,4!!'/,E-E3-A-GH7HH>;B362*H.061B'7
@r1665
CCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTT
+
2H(#?"1FE96:G).611%0<$3'3GG0!=B/E+7:*/5*0=H4C.6:6)?#?5)5#"G=974%G&)'60'4E,/!57%!3><,
@r1666
TGGCAGCCTCCGNCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAG
+
F?2)1-!8+G2E4*B?562>6/%D<83?)@<2>-9"1."C71<>+"D!?!!2'
@r1667
TTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGNCTGAAATCCAGCGGATGCATATCCGGATCNCTGAAAAACAGGCTGAGCACGGTGTACGT
+
A21C%2D?8;A$9#,D-#/6"<AC;),3D:+HH%3,A+A')!!A'81<$#8#F06"@*;+06'-A#!6)0:2198F)81>570.63=9-1+G(@0-G7+=7C=CC?#-7;F&;AGH+
@r1668
TCAGTNAGCCCCCGNCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCNAGCGCGTTCAGGCGCTCCTGATANGTAACCT
+
=E,0G%;A-G6)E&82>,667AE/+$3/&*-*?<-5;:8/)3#7&6#4(,+$=!(,/0G7<E?B2C2F2:E8.EB4-9@*5F6+B4:@)%.0#'!!7*'.9.48"@./911+
@r1669
NATTAAGCGATGGTTTTAAACATAACCTTCTTANAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAA
+
"HD-2@B8H75$'60D-&3%#<'(-A15E"90.F-/%C19=8FB+<H28%("E#.@&H/B&(9B1-*H%.H#G'D@*=@623F1@,;?%5
@r1670
CGCAACATCCGCTTTCCTANCCAAATGATTGAACANATTAACATCGCTCTTGAGCAAAAAGGGTNCGGGAATTTCTCAGCCTGGGNCATTGAAG
+
?!,DDAA2**<-/HH5;0D<$D&'G&=E1-20-$%6#(E"$A8/@(?G9,/%8E'8%-E-(%'%/HF.D'9&:$7(,.'#%*E3"H>=709(D9
@r1671
NTATNNCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTTGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGNT
+
#)&(#"++(''*!+'&+#!&%)*!*')&$+!*")'*!#++%(*)'"&#'!!&+++&'#"$#()#)&$#"###$$'"((!'""%*"+&"&'*#*'%'**")''''((!*"+)"&!
@r1672
GTTATCACGGTAATGATTAACAGCCCATGACAGNCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCG
+
@?B;C@B3CH0*"<#-FAA;:$@&*#(<@!'4;(@D+9(:G,8E8>9"$;(;$9C@6$CA+<6D?5,%3E=H(;*BB&B.D4E$7!(9<D1+($9(:$&#BDC@7/E2D5<*?"=
@r1673
NNGGCAACAGATATTTAAGGGGAGCTTTTTGACTCATTGGATATAGTNATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGANATTATTTTTAACCCGTCACCTCAATTTTCAGACATTA
+
!!9E%E&'?,,%#H)89CE!GC&%9?@3G0BCB.A@>1''%!#D9@83C4HE--#(#E'5'=F65;282AA504D1F/"5F67C@F:*$C(9A5$.6>,.7A98%%E9%(<&%:&;E=109C((H"@=E=
@r1674
GGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAG
+
-5CC;5=35&"'2D:+@3!*632>14)/+?C,D21+%.=EE.687"3G4B@<5&>,=<9&1$D*<$"5":D8>.H7GH3D:A'H/4,!".7(++C0#H;F13=E,"9/&;%,)=HH92!B*@5@5!-
@r1675
NGACCAGCTCCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTG
+
"(238&1D>>!+)=CG*.*+E67H/B,#E<34B9HB>C$-3-#
@r1676
NGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTT
+
+H/?9<79#C=H8=7-(53#+E=8HH9.03A3.F>!2'@F8.#"BC@0E:F#EF&C8>
@r1677
GGCACAAATTACGGCGCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAA
+
+'A79;.6-E0A!?:2@@+?!:2)9G*7&>7B+5=8("<FF09(;<'E9.5;-7:.95A8B3@;"8?&6$'F
@r1678
AATCATCCCGGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCNGCATCTCCTGCGCGGTATCAGGAC
+
+C@5B7;,?<?0-GC>!$9,GH?70*#)D"F3DDF0=)<F#";".B#9A4=";;EA@-.6'075%9F>G9F%D=9,E;B9:CCC:,A
@r1679
CGACCAGTCAGTGCCGGACGGCTTTGGNGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCG
+
BE=,H".(@"A.+DG31<F#1H=:.D9G/E@+DG327$.8''/"'A=1,14?B@A!*516'@!(@<4=:<DC'?4%D+H7!<:H4A*8-D%5"264,=;,=H=A76:1A
@r1680
NTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTA
+
-AD1")39+'D@!9-/'%4+.<$!<#:1%43=.C1)6746F=.8AE$5E94HG"*,>!=7&>D4$-3(?3C*A7%"%!:+&F$1C6)8*8,)A7<>0@;#C&DF"-1@7(7B&>G2!1)4)*C641F8;4(0A1F&4-G=2:4H9@HF<&18H@5*A!*E'5!)5-,'9G-4>DB34"?-##61=4/+<(5'A7!#(E8@%=@$($B
@r1681
GCNNNCCNNNTCTNCNNNTCNTTNNTNATANATCGNCNNNNNACAGCNCGGNNNCNGNAACTNNNTCCTAGNNGACGGANGCCANGCGTNNNANNNTNNNCNANNGGAANNTCNNNNNNNATGNCNTNCGNNTATTNCNCNTTGNGNNCTNNGNGNCNTNNTNAA
+
$#"!!""$"$!#$""$!$$#"#$""$#""##$#$!!#$"!#$"$#"!$"###!!""""$#"$$""#$#"$""!!##$#$!"!##"##""#!$!#!!!#$$##$##"!##!!#$!!""#"##"$"$$!!"!##"""!"###"""$!##!$##$$"#"$!#!#$!$"
@r1682
GACTTCCGTACCCAGCANCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGNCGTACTGTTCAGCAGCACGCTTTTNAAGCCATCCAC
+
!*+!''##&#+("&(*&'+%+$$''&!$$*&!*)+!()$)+$#"&$#(+#%(&"(($%!''*'%)*)'!"&!#$*)&+($)%("(*$'(()(#(&++*&'%''+#&+&%(!**'"$%(++%#"*+!+'(+$)'+!&+'$&$*$#"$%$!"!**+(!*'*$&"'#+*(!
@r1683
TACNGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGG
+
'"+!"*$*"$*(#*$%*!$"*$&%!)')!"*!'))!$!%)$)&)++"+%)%%%)*!+%'(#$'!(%
@r1684
GGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGT
+
,6(-8C?9<!$D/H2/!*)9G$$1//"3,7!+$-=EF/<80-$:F.-C'!3)9%4<3-%H?*4+#&F,B7$<-(#GH+0#()/=?!GD6?/2BE?@"0B49G%-90BD>F2"1+%4>,$<&<@%-C"5A3A3>*1,!6,$-<'"9<4-4+01,$?E*&B/G#+H.'E)#88%.9:,%#6D315:9!%@G=+.
@r1685
NGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGC
+
!F:,0E#+$H1)?.8@0;3/4;!**=:.:</)#4EG,ED&9<B17!,)GCE&".'<!/(
@r1686
CGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTNTGGGTTGTGCTGTTGCTGNGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGANTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTT
+
?82F>3:%/&BB.<EG/:,;.0=3(-;HC,>5(D1(3.;35*B@==!=*"GH1/A:7'76#%29)46E83G""/D3$0>H433<)2#C.2@F"7C,43*,227'5=H;#$)*14$.4GHCD6DF0@<37"8B!#84#?:D7D/@@3D/4C5;@B9$@<?!(<9F,?,DB91&1FF31F';5E&0;GFA."?1A%2:2@H"?A#%BC".!'*;##.;G@'9!/748--#7C6%"F("?8
@r1687
CGGATNGCCTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGG
+
%'&#*"&*"#+"&*('&+'#"'*!$)&)(*+))&!(*)"#$*!&*(%&$*$)!$
@r1688
NTTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGC
+
$H8H:-B>>;=<0/4$%*6+%&'?6.D*/D3,*69;1##!#979;'<4F87(&<,$D").D@.E&6!"%//1GD(0%4'%7@=-(*<@**@%-)#"9GF&.(HA/3/1D(<6F=?BA",'4;F1)FAA>H!5+!%FF5#&H@=:;818BF:-#"<$$)&F)1&/BCF@<=&9BH0*/$F;8&6,$G=;2,31'D-G)(D+E5/H,D;&>#3%B-<&)48+F*?-4G,=+&B'!*-/AH@@;8%)F#?,A(2"<1!G>;
@r1689
CGTGGCTCTNNTTNNGAGCTGGAGACAGCGGTGAAAGACCTGGGCNAAACGGTGTCCTAAANGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAA
+
'$%&%#('$'"(*#+("&*"&'!*$+"('%!+)'((%!)(((*'#"""("+*$"*&)#%)%'$&%*$(*%"%$$%%!$&$+'+*&+$+&!((!)%($+$%'*&#)**''''+%*
@r1690
GATGCCGTTAACGATTTGCTGAACACACCAGTGTANGGGATGTTTATGACGAGCAAAGAAACCTTTACCCAATACCAGCCGCAGGGCAACAGTGACCCGNCTCATACCGCAACCGCTCCCGGCGGATTGAGTGGG
+
?2>*='@-$(*C-C/.:E=3=&9>0@4C:*'D;&,%?=(!%?.(?=$A$D7(#<2E/<0:8$93G+C@8$BD#(!!G!4H3"7#=0/)7+,??7A=-;/AG*D/A'<9$<#A?H86/CGF#4%26*"G(6G</.=
@r1691
CNNNANGNNTANCNGNNNNNNATGNNATNNNNNNNANNNNGGTNNATGTNAAGAATNNCCANNNCCTGNNNCNNNNAGATCNANNNNACNTNNNTCNNGNTAGANANACNATNNCNTNTNCNGTANNGNTNNNTGNNNTTNCTNNGTNCNCGCCNNAGGAANGGNNNNTA
+
#$""#!!!"""!"##$#$!$#$$#!!$!"!$"#$#$"!$#!$##$#$"#$"""$$$$"$"$#"#""#$""#""##"$"!$$!#"""$#!!$"""##""#!!!$$##!#!#""$#!"$$!"#""$$$""$#!!!$"#"!##!"$!!$###!##!"#"$""$$!!$!"$#$#
@r1692
ACGGTAATGATTTACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGC
+
D)!821#@;."@*&#8DF8-E(2%-BD,/-$.5)1+,"G@0;)=,>C!/8>HD<B+?HG'430:D8,@2B392H7A:
@r1693
GCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACAATCTCGTCAAAACTCGCCATGTACTTTTCATC
+
:)#0#&FFH)F0=6F#<'6$AG(5@-;C0>4A<=2904",<,F'G%6.A'/9<86?;!?=B@&%+B24!DC
@r1694
TCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATC
+
9;E4@67DG+2';'!>%;3:;ABG>DFA!9+1>!G=9=H#!%%<>29*
@r1695
TTGNNAAAAATNTNANNNGANTTTNNNCATNNCNATGTGCCATCNNGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTGGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTNATTC
+
**$"%%!%'%%")%("#"')#)$)!!!###!$$+$!*%$)!))"%+("""'$+(*"!!+($(+!#+(&"'$&%+%*"'&'%$#!"#**%%*%*"!++$#%'+&(#($'!&$(%('*'*&%))$&(!)%*""$!&*(+"#)+%%"%*$'(%%)(+%*+&*()''$!*+#$)"('(!*$++&
@r1696
CGCGTTTGATTTCCACGGATAAGACNCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACA
+
G?;4#%G1'?,G2<>?:BGF'-A?+!E?8!(0'@AG5E(6B(:1%*(!45-*)7C7097<&4GC,<B31G49%C/56,47+6?6**GC5C*01E;A06&C!+":A*$2(FGE*$!B$2D*7#5DB*@!.,/*-268<#?
@r1697
CGAGCGCATTGTCGAAAATACTGCATACANTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAATACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATA
+
+0=H39<,C>H673>'#0)>CEBGC1$52DE!):C8;B7G7*<+3:3F-9HC1%A?G3H41F/<3H31"56$)'=D/+B=-AH23?<;*>030.=>C=F&C;>?=8=+=7)9$<*DH9+3.56(3B?H&../$>D=<-$<G9,/+D30,!;'C2E'=
@r1698
CGATGTGNTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACC
+
@CD>B'A:&F6-CA+",F4="+1/C-A+H*+D#+E?6///0,3+6/H:<03/.(##&=-H41F5
@r1699
TCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGA
+
5:5.')D6390.*8,;+/!>-G33,E08+-#!<E%"'1DE'5;C*,+-4*-?==:.9C
@r1700
CAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTNTA
+
0G789>87#?,(0#E*:!24-=7CAF=%G(2;"EE&7%#.,+/&3-+!6H/4=3/3=D0@><--;--3&G/?7=4<A$5H+>00F8"%;D/>*6:F::*H0)%3,.*:B=D6@:@)/;2=4HA02CA*C7&+BH#,
@r1701
GAAGACGACGCGAAATTCAGCATTTTCACAANCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCNTATNCAGATACTCACCTGCA
+
;>#H;0(-,C;?=<??%1>!D<;F(4"$C/&3;>F415>"F!8)%B1GCA:;):!#3<+.%+H,<FG+$,H$"@D0;7C47.A,6;)"1:&C+H)G07F:).96365(&.-39
@r1702
TCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGT
+
5)8B!.6*E<(5F*$H?6:<1E-6/@6*H718'&;A$5E*"'<
@r1703
CCTGCGCCGGTATCGATATACATTTGGTTGGCAATCTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTNGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAAT
+
*(42<B-2,A1)#&5</=EGA0?)/AH=76"92/:;4F+)34G@0&902.C%,C?>A/"7%93+-"?G>17$9F5+4201E39;0C=F6BA69-?+5A%'$3A&8;>9&;;8EBF0)#C4?'39#$/)(=>3-&"0'A!6E/?(6*<B'$/.H%@;<27,AE.#=(A8(.?F44H!A:(4H?33B)+'=#0A.F%4
@r1704
TTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGNGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCNTAAAGCAATTTATGAAAAAAAGAAAAATGAACTNGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGC
+
0@;0@<.#:.%$'%<.A<+A&D1"*G/(5.,1$61$,"6>:C/%=AC1<EB$0&%'*$-$9/,%"<B"H3&3<%8!7:'1:!%526=$014;)F,(B!6&D1#(,<"361H2#4$&4#F6@.8.$6*5@<F"#74F0.)D5="-#'BH,;1*74#7#8!8>,!219F,E"">3:9)(B@6GAE.787G71/4%76!8$CB17&8.)?)6%%29B$@5!/;1B%#"*<=5C,@&6$@(0%*)0.27B05>&,*!B(A8.HC+HA6)D9@'.?
@r1705
ACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGGGGACGATGAAGACCTTCCG
+
GE58BG.H'1+ADC5-H!#/G!8*<-:!/042A!9,A+@/2/H0)A'6?*$5%:B.(!8(29%*2,'50HAG7H=0D=!$=+8'D9"*:<
@r1706
ATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGANGCCNGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTG
+
A+DGF8;/(=45CEG'?5+H56#H'CFG8/C'.%1E&C(2#*$#/CEE>)@"."G1,/H4',A48@4E%!;#;)1!E#:H&10A$3/!B<4-%5(8E102F-C?G27.!26.3.>$:%GG
@r1707
ACCTTCACGCCGTCGNTGACGTTCGGGGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCTGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCC
+
B6%-B>49B!F*&62,&H?7?8562(6%%'C72(30*"4=*E,1*>(3A213@#G/E)#1!4G5=+*-54(<%&%=?*//@5E;8H=<*G2>02*(!=@,(?==C%)8AAC2(-D"80H;F6:)C?2-G>A
@r1708
GTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGAT
+
<F"<*E8?-,0?,>%?$,D;+&=(4(0)C#(=/$((B+&3'F)C6,EA,18G=B3H(-%3AF/1>$<GDDG$&(@'F&"B.(+@)?0('/>D8/5,(370B4F-A7HD2"-(
@r1709
ATAGAAATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAANTCCG
+
6D5#00,'?=E$>5$'E?79%BE71).HBFF0/!.'2A9GA%.,=;7(17
@r1710
CCTCACGATGAAAGTCCGGCATCTCAATCCCCGCNAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTC
+
6EA/DHA4);-#!A5GD>>!2D?:G.<C<=C3?')F+H;A5#6/$!95>!'(@@#+<,<"%DG+4$035*:7F7<?/A;&H0275
@r1711
ACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGT
+
(H(@G>(@3"C!5-EG)%'1(AGG,<?7>F;-&0*>$:0E%;&-=+#('GEG#'D9&!5,1,
@r1712
GCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCAAGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAAC
+
H%*&01?G3'/G))C67#$;#=-E"8,8.(>.43-3;;$&7DH1>BFDC>2<9"*A2',F.+0,"-$E:3GD1(&F,#?8HD>3+?@E0552;H53H%D&6G?,C)15/F'9>F2!%>8875@F*@@187@G@C<F=FE-E)BD2B".)A3CF:A*C+#5(/ED3H19='FAF>@(9>@D:2EH#*80($".!?BH<C?4
@r1713
CCTTNATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCTGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGT
+
2&0H%4.?F'2F/0@D#B5=?G)(6@C/$/5/A0.&*A0*B!*<0:>BA#6?47'2E'*0#(DFD)AE!"&"+80?B,/)6+62&*((H34=#H++)2@B!(9!&64<GE:4)<6-:AD,D!##5)13D"FHD=D?E5
@r1714
NNGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTNGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCA
+
"%:-)?60<9)#D@7,9+B&).&EC>"))C83;4@EF!8C7D71C#7$"&/).(G10;H18-4D,3112/?F-4/%.'<<5:!G*3E
@r1715
TTGGCGATCCGACGCATCTGCTCACGGTCTAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCATTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCT
+
A45A<H)@GH<7&F+E>,>?%DG&=3B+1C&C1<+<#407/3A/#E8%D641+3$C-A,&*'A*9CF:9!!$=>3E!E8!:;9',4E('(>++#B:6+<=H1:F>(H40,-B;/8?.'!6C3+B'<B$!DA?
@r1716
NACGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCNGATTTATAACCGCTTCNC
+
!&%)$)&$'&+"(%#!*%#+*$)((+#'*#&'!""&$#%$&&$*$&+&$(&)(#!)"'%!#&$+!&%'#)#$&)''*$$!%')"+*&$!*(#(!$+&+')$&!&'#!!!+(+!*!&'$#*!*'"'$*(&&)%("'*'")'%'))++(+(+!)"'$%&#$(!)(#)&'
@r1717
NAATCATTCAAACTATTTCGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCACCTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATNTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCG
+
!B/$=%E<?*:F";C*6115?/AD3=C$6=@$0/*%7&DH,1B3GF#5EA5-=?0,-/A9*E!(53'E<8-&A4<*A&-2A!(C&:2#D01.;>9E:.AB#1'41.1$2:8:=81-@BA&*B9+7/-2G'?1*8($!751#H@9D!"4?G>A22E%53H&+@+*F3,=/7."/8B),EEH;13.E#>A=%F<>69+8<$".A08GB@1FB2EH=0/;&("!E("5)&)%F1-B/9&(2DC(03G%//5-*0ECG/F*,G/@+=+*7')+HC-)66(<"#H9*0?-H:/'=(48"/.#F)/2G,*13?"-,>0HD2%)0/.69G%)6(+66+AEDE!-;:(B1#.8"!=&49B5)"GA.
@r1718
ATTNTTCCNTGGTGGTTGACTGATCACCATAACTGCTAATCNTTCAAACTATTTCGTCTGTGACAGAGCCAACACG
+
%'&!$!+)!""(!#((#$%)+*'#'$+#$("$*$"'""(+)""&#)'*(*)$##%!%%&'&'+&*&$+#*#"(""%
@r1719
CTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTT
+
<*5%;C4=%9C"/7679-E2G#&3@:=@+/D-A&E#4$/)<"%
@r1720
TTTTTGATGGTCGCCCCGCTGTTTTTGNTGAGGCGGATTGTCCGGCAGTTGCCGTTTATCTCACCGG
+
*#+%!))+%")$#&$**(++$*")!")$"'&'("%*))+!!$($)")*&)%(++&("*%'('+&!!&
@r1721
CTGCTNTAATGNTGCGGTAAACACACACTTCCGNCTTTCTGC
+
5F3$96:4!=!(EC.9AH..5GB"!$("&%3"#>+,*=CA+?
@r1722
CGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCCTGAACGTCTTCCGAAAG
+
C6CC=?:5CC</;F-*@GD9!/:3A'$:?*-/9-+2>=B!18AC<2-:'%*%-#72+&."@(B@'-G6))(%1B992B;>=#!G3#4A@4%@3G?#ABD7
@r1723
CGCCNGCCTGACTGCCTAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTNCCGNTGTCCGGCACGC
+
$'!#!+(%%##)*$#+&*##!#($(%+$(#!!("'(($(%"#&("!()%$%#"(!*&)'')$+$"))+*)(#&&$#'!)()#"+$()#''!%$''*("'"(*'#&$%+&&&'$%*#&+$!!""&#
@r1724
ANTTNGAACCTTCACCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTG
+
$&&(")++*()&%#!*($*(*'+*(#)%'+%%#%%(#'++()$(($*')#+)&))#'((('!*)*'+!(
@r1725
ATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGNGACAAGACACCGGATCTGCACAAC
+
;4.(+C);,$@0H"29E(!,CA54!-E/BE4>;;?161C7887C48)CB!H&FA2/:<?%#0@/3<94:,>4&/'#/=6&)*9H>?))H
@r1726
CCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGNACAATCTGGAATACGCCA
+
9!"BE!72&AE<H:B==!1A<D;E;2?-?H6*5C4@-->$7*4/*H@A+;+<?CE#?<;"G-483.-H27@FB90./:+8A+:F+)51"'GC@(
@r1727
TGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCANACATTAGTGAGTTGATTGAGCTTGG
+
9D%#F)+7'#+530/>*9A(+4&%%@$C4)<=&C":,/+'+*-/?D%5BHHB-2$%C1!2>52EH;<=/F&,+"H+(G!:*<0C./:D
@r1728
TTTCAGACCATCGATGGCCATACCACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGNTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAANATCTGGCTCGCCTGACGGGATGCCACGAATTNTCGCCGCCCCATAAAGTACGCCCACGACNCGTTC
+
>;G?4((:'.#!C@H,'#A-6FCB.?H#B-)796E14A$@18!><9"<F8F%3/>/-<F$=.#/461F:FE.E)!)29&>!:*"E?H4-.C5">$!11C?'$'!D,$8"H;!9H+B+G>#6C%H*0=/6,2#?$,0#BC/.;B4<H.+2HH+@#1&8H$7FC'58+AB3+3=&52';F64B=523:A$E-&8*6DB'F=<7&>.F6*3,E2
@r1729
CAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAANCCTCCGGCCTTTT
+
---G7;H!H!6HC7>=3H)H;459)EA,;/-%7/37$HB.(4=+:%::>4*,F0%F86/@5?;7FH<D!<!7G>,$C**
@r1730
CNTCANGGAGNAGNNAGNTACNNGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAG
+
'"*%$*(*($!%$#!!)!(&)!*#$)++"%$#%$#'%""(*#%($$#*(+#$&%&"%%##((('$&!&$$'!(*#)'#*'&#&#!()"%(%&'+&*)#$%!)""+(*)+&"')'%%(!)%*&!$+)$)&)!+%!#$%##&(%*#!(#*&"$*"+$+#&$+#!%*!!%*$($'!'*"!*#))('#'*""+!&%$$*$
@r1731
CAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCT
+
3A3E5,:%4@G1#&"%*"@;0=@*<!'C*4,-.-5'>1C9<=G523'GFD3=#>4H*7":@<:D9%/7449H6?C)F0>+0"%/F"
@r1732
ACAGGCTGAGCACGGTGTACGTCANCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAA
+
32H2$32'E8.$*%1H"?-*@!$"*48>#"+-$4-%754-26H,6/,)D?GB<EB2%D0F3H1D0:!1F/5<$.-.A
@r1733
CCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTG
+
47HGCB"2AC=1&896A.%(;.3$$$(&?5F#A/!%8FH(,/D0%!>3DD78DA!+0.#*!A?$<HBH>#/1/
@r1734
CATNCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCAT
+
E$@0*:.*EB@$7=/,>$0?07)1/4A##:E6$1%#AB?=.=%!975&3#9;*<4%,*<2-D/-
@r1735
GTAACGCTGATGGGANTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGC
+
,2.>AD?)BD':?@E2<+A."-:007/"#6!0?+A#;DC+H7>;AH@*D<'!DF)HD?95)6.C+9D0$?E65+53?2?-"C/2GA0,7
@r1736
CCATACCGAATCCGGCTTGTGATTGCGCCATNCCCATAGCAGCCANCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGT
+
5GDD2.3,"H%6H;(E;<35DE"F$+==9>'4*98HEF4*!09F/+H.2@8(3,0,D6651>$'3H&A>@#,('!6FC4'*?=3$(5D<"=9,
@r1737
ATANNAATGCATGGTTAAACCTGAAGAAATGTTTCCTGTAATGGAAGAAGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCA
+
(&)''+!)!#+%)((%#%&+#'!!#*(")'+"'"!#')!&#$!()&+(*(!&&#'"%)*$%(+!!$"!&&"%*$)#*!&$'((#'"%%%!"')*!+!##('*(%)()$)"&!!(#&($'#'&!&+$$$#&"*+%&""+(#""*"!#&!%&++%$)'!(!('+'+()$#+#*&"&##(
@r1738
ATNATTCAAAGTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACCGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATC
+
;66E=1/!836;;:#5<>)@%+F)B="$D&@G1+=DA6$!=1-,DA>;*A$>8*;$D4D@2'$%89E?40.A5/.=66:%/'=@1/-CA</&=5?5D!2+>5"%A%@'#$!G2)C!G(;
@r1739
TTCCTGTTTTCCTAATCAGCCCGGCNTTTCGCGGGCGATAGTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAG
+
+)"*(+*%('&*)%%(#)(((!#&!%&*%(%'"$'+*%"$(+$$%"$"'#*&)&#"+'&""&$)'++"')&#'*&$#)'#!"($&%**(
@r1740
GCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAG
+
?D.&$/(:,=??2'##B,&<A>D'$/FH'GE>:(#+&0'8,&-<@">.@B&#=
@r1741
TGCCACGATGCCTCATCACTGTTNAAAACAGCCACAAAGC
+
':-1"&<$C<=B8A58C?/)%CH8A>C<2&*E3-*@1/+#
@r1742
TCTGCGTTACCGAATGGATGGATGAATGCCGCCNCGAACCATTCAAAACTC
+
0"HB!9**%>6B?@=7&%0H.&CD@5-!,2&D3@(>3B??A0H$+%E+2@F
@r1743
AGGAACCNGNAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGANCAGCTTTCCCGGAATTACGCCCAGATGAGCTAGTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCNTCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAA
+
!""'%)%#'#+()%*##)'&)))'+#'%!$')()&(%**$%&!"*!'!'+#%+%'"!$$"))%)(''+&%&"**'*"%%")+(('%*%"$&$)%#'$%*'((%!!#)%!*!+)%%*()'%*)$&&&+'&*$%"%+#!(!$"!)$"%'''(+""&$%$+&&$($$'%'+$!"&*+##(+('$&#'%&+'#(*#!)#+$'#"'$&$'##&&#%$'(!*#")&)**((&'%(%$#*###"$"%))'!#%&&"(%$'')'(")$&'!%(($#(!)+!&
@r1744
GGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCANAAGTTCANAANGTGATAGCAAAACCCCGCTNCGGAAAGAAGTGGCCTGACATGAAAATGTCCTATTTCCACACCCTGCT
+
<*+"%4$A7G!5-H"C+$)-CEDH(2?1,95#<A+#660"-3=2@)=0A3G9?F51A,"1'#"+19<8#@C.9>$1+@.5$'$-D;"9B265(:*<F#H+.7E,)>D71D/%H=C)".9)//9!E5G
@r1745
AAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGT
+
2"<=G&"0&:*:<938@)?9C!$G'.<H"'FBE9<.?E64G("%-5F2-+8#%6>8E5A:$B+085,=,+C"8;6H'7-)<7E0A(8!*<4@0"&
@r1746
AGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCC
+
3//%@9(F2?#6G!/>$)$1(H<<9&&0)*E;>D!/'A0,?4=:&8D3AB<"/D8!%43G;
@r1747
NGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCNGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGTTCGACAGAATCCATGCCGANACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCTTTCGTTT
+
#")&+'''%"%(+&(!!+"*(#+!*"%+)%!+#*#!&#$(''$)%!")#!+)+)%*(%#+*&"***$!"#$%"#+'&"#!!%%#&(+*%)&$#+%*#("&&*)#+%"#"!*$!&""##"%)$#*!(&(+""%)$!)#%$")#'&"%#''
@r1748
TNNNNTNCCGCNTTANGGNNNCACTNANNGANNGNNNNCGGNCNGTCCNG
+
$!!!#"#"#$!#$"#"#$!$""#$"$!"#"$"$#"##!""#$"$$$!#$"
@r1749
ANGCGCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGG
+
&$%!('+)+''!#*$!"&*#'(+#(*+"*!$%!%!'"'*"$$&#**+"!%(#"$'*
@r1750
TTTNATCNATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCAATTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATCGCGGTAGTAAAGATTGT
+
-8(0F'*:GCC:4,(9A,%70B:#+6)888$.#!-G,.=#345ABB=87+D)76G7+<FE7+7A<F4:&H90+"0-#41,EA=$)H".-0;"E!(37$#<6*6D@C.!:154(,5DC04C)&5<7*%
@r1751
GTACTTNATGAGCCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGG
+
&*&$&(!%)*%&%((&+%!#$(*"+&")&+"%'""'"'"!(++'%()
@r1752
CGTGCAGCCAGTGACTCCCCGCATGTTATGCGTTTTCATGNTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAANTTTGGC
+
1'<1>./..;8)*,E7F0.G3E'HF3FF!2,'5B)E;H:358>;E/*GBF3C1"H9&8C:1#!'C?)2>"9#8-:5?%$B90E/
@r1753
TATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATG
+
501@9$+9&,:64;2=?(*GH5;"'DD:"&:<-$2?>8=4;"=G@/';32+"D*8(F<(4).?C436$/,>.D9&>(/',01GH.7-H3?4,:'*$C*G<)A
@r1754
TCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAG
+
*/$@*(8/#F4,*A-E!344)7+4/'"(G#@A(/096.0F!C+48)AE:-!D9=))&'++B)F4E;8)1)C"6F#4<1'G+
@r1755
CTGCGCGAGTGGCAGCGACATGGTTTGTAGTTATATGGCCTTC
+
3.!3>9>D#2?0C-A44&,7;64,!?6;!A::H<A#"*??',*
@r1756
GCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCA
+
/*1E8*'$8*7EDB?=F2.E#,)'82;:#-@.1G9$B547&2G/
@r1757
CCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCATATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCGTCTCCTGCGCGGTATCAGGACGACCAATATCGAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTGTGGAACTGGCGAG
+
=%H?GF=:F&C*0.H,-/6,8=4!8:#->3<"*@*:@"@C1+,*+?+!B*<A5@98?F<6@G*$#H<H-A,E56!0&;4E4$"?E;=@1$:?2<,"(1A.H7'-$&8+()0H%>1$H'+$*A.((6(6-&>4677?34+#(42D'+=?<8G<<8*='G:0A4!=?<F5*;#?E4;'&D')#4<26BH6(H8=H7.?*!<6B("F=:!)>@:&477(-A"#E"?,(!G'4C(/D6#.<9&1+2$+E;&@F3D+&,,%10H&(EH"."&AC?<B1?$;'<C0)!*,%@7GAF1E?F>31;%""6.,9D.#H74:8099FC0/:E&9%1#G,H;DA@DE=C19/*<$;8A0*B68E'738;,*9'H&H#+FF9+64;>3%@")=:'DC.)C#'&4>'?)
@r1758
NTCGGACTTGTGCAAGTTGCCAGGNGGATCTGGAANNTATCAGTAAACAGAGAGGTTCGAAGTGAGCGA
+
+1F6!"E,A%7.)B&1H$>)9H?#$>F5--/CF0(<##=G(4F;84,$>1-=E6;&"D(.D,.8FHB;,
@r1759
NATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGGCAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCAT
+
#>>8?0A-B-"08"C+7@0>)#:G4.6=0&DE:.-"0/16#%<E0@=,@2083>5&?&6<A*2.&6A=%-<C:CG@*>21>A877."3;="#7,'8<04&-/'%4D?':@)"$48CH7:#FB&3;4)6H2#7=;$;B'-#&#30"@:8?.:>/F':6.7#
@r1760
NCNNNGGCCGCNTACTANCTNNTGGGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAG
+
!("''%*%($%")**)*$'$!#$&!'$+)%*&%)%+%"!%&+#")""$!*(('())'*')!''*%)()+%+!"$+'*"&!'$(+(!###+"$'(#*)'*%+
@r1761
AACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAAT
+
)F,3>&3%65D6C5?$G@2>&'21-*>570C%$0$*@44(3/A5A1$B;7242:@D*""F!"B0?$$)($0$F;5?%(8&,8#AGG0A84+0G81>/,E:7=&;."AD&@D1A708
@r1762
GACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTA
+
E;00(9-/%;51#0->"('!.,$*"')$"1@HC,8+?,++D0'/AA6?(/(;"-8$E5$:6=
@r1763
AATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGA
+
(G++.1)+@&A=@!+2;'2"#A9=B/,BE4E1.,:F'ADG.H-)>F1,3&F%A$
@r1764
TATGGAGTGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGC
+
*,9*%?:A%,?+E6;'0;8/2D,C@C'8/38!=E%,,F=<*D$@A9D%%F(6@>41
@r1765
TACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAAACGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGTAACTGAGAAGACAGCGGAAGC
+
)/C#/DF;0=*"$.&.(F"D0"AD/31'*!'F#$BH@48<-)5*2C/;!#GG!A>"F30)?A!*>.#'("2;#$4E9:47#%4-E@E4;6(=D#09'-<463*;
@r1766
TCNATTTTTTCGATGAACTCCGGCACGATCTCNTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATA
+
*%#$'+(!#(&+%"!*)"#+)#$()+!'$'#""$)%*#)#&"!*$*(**%%*)+!)&*!!"%)##+*+#)+')"(($
@r1767
GATGAACAAACTGGATACGATTNGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGNTCGTGGTGCAGA
+
/.CG/B09/?F4CF++1$BE<!*<0..;"0&(*C:EE/.</;85-G:3&5-69;,&3D5GBCD##>E#D1+>;$!17/F,.F!B
@r1768
GGGGATTTACAATGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCAGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAA
+
,E02A,H0.D4=%CC>34G&/1*1C83?:3#<$(:)E%C@9:$+4/;)>"C#>"7;.;EB0*H/-#3:,5951*A4H"#"A'.=GDA4<#3;."3==-(E>=
@r1769
GCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTNCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAG
+
9C16'#<)*E*11C=B=8B@8E7G2#F'0?<==(#;:C9;?9$?C<A/A."2(-B5D()H:,.FC2&&1?69"8&E5!>D1#;!>#'C+"E
@r1770
CTGGGCATANATTTCCTGATAGTCGTCACCGCGTTTTGCNCACTCTTTCTCGTNGGTACTCAGTCCGGCTTCTATCAGCTTCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCA
+
+'#)*+!')#))"')%)*#$)$)%#+''!&**%")($"+))#&%*#!#"%*#(+))(#!"+%#%+(%$"+'%)'''#'+&#)!"$'!&&(&*+")(%("!"#)#)(+*')*&'$##*$%
@r1771
GNGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCG
+
)$=6,#"")?/B<+8,),B&*B1)8G:3E)%7A'=?E*DCCA6@525/,27?>?*+(&!&,;)64@#E-A-,%>HD9C<(D,45*#);'<$=
@r1772
CTTTCATAAGAAAGCTCTGAATCAAANCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAA
+
#9E10-8<-CA&9>4;?7'4=7>&2:G-'@A+F''5%&8"4@7%:A/<&DC-/"*,40-(6.?G14.+-':>','7A%"/3G-G9G#5"</A=:(;*(9?/"310-@41./A-9A
@r1773
GCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCG
+
><4(E7E1.B$D?$9@F,:;""(1##.?),35-8-0G6)>C&&H''A659(#GG7=5C*F/<)<$!:'@'4H8GFB3<:"E1&
@r1774
GCGTTAATCTCCTGCCTGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTCCGACAATGCGCTCGGCTTCATTCTTGTCATAGATACCTGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACACCCGTTTGGGATGCGACTGCCCCGG
+
*&";--!E2>#G1;D#FF%0G?<1#0?&?*7G+C?/=$42;("=A##?(*-949$$B0.:.5&&$46():9D#,2#/<A66$18/<!"'.GG-"#=1-)33&7=%-A<B6,1!#+-F!21H0E@G+(C@%?/+AH;3$D$1*7C3<&/HED5/;E+D:6HC$:772>D!##:-:2=CD;C2<055H))CD4"!:.9*
@r1775
TCANNGNCGATTNNGAGNCTTAATANNNGANNGGGANNNNGGGACNGNGGNTTCTNGNNGTCNNAACAGNNNAGNGTGNATANNCTNTCNCTNAANGNGGANNNGNNTNCAGNNNCGGNGGNGGGGCCNNTCTCGTCCNGNNTNCATNCGGAGNGNNNTNTANNGTTNNNNTNAGGATCNNCACNNGTGGANNCNTCACNACNCTGNGNGTNATGTNNCNCNATTCTGGNNGGGAGNNANNGNGNGTCGGAGCNANGTTTGGCNNTNTCGNTGNCCACNNNCANCNC
+
##""#$!#$!#!$"$!$$$"!#$$#!!""#!#$$"$$"!!#"#"!"!#!$"!#"!!!$#"###!"!"#$$!!!""!#$!"$"!"""$$$""$!#$$$##"$!"!!"##!#!$"!#"$#$$"!"$""$"!#$$$#"#!$!$#!$$#$$!#$#!"$##"!##$##!#$!"!!#$""!$!!"#"$"#"#"!!"$#"#$$##$$$#"""#####!!"#!"#!!"!!##$#$!$##!$$!#$!#"#!!"!#!#$"!$!""!"##$$"#$"#$!#$!#$$#!$#!#!####$#
@r1776
CAAACTCTGCGNTGAACNCAACACGCAGCATACTGACCCGCGACGAC
+
,E"8HD/%8D<=A:".(/<>F5B'H:69)<@H?038>=$#8A"*$;%
@r1777
GTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAAC
+
475,"+7(8E2>;25,/CG:H)B.,(0+G,"0FG3,*D;;'5:<:*#?>
@r1778
NNNNNAGTAATAAAACCGAGCNATCCATTNACGNATGGTTGCTGGGTTTCTGTTTTA
+
%!!#+!$$$'*)!)#"')++*%(+'($(!)""$)$)#*'%(#+#&%+!&)("#(+$%
@r1779
TAGACGGTTTTACCCCNATGGTCTTCAACGAGATGCCACGNTGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTT
+
%A,,?=3%.A9=F!3.G+.+12+,81;6#/.;D!467@+-"8$F.767>&B">#;4%8/?A$D!*:AC3G9,1:;0)-@0!5)A-<H)%&%0-H%7=9;DH.H/H/>-+$FHC/D54&/-%#'C#?C*6,88"0!F531/DE&!;&=B$H1%5?.>$!:>G,.'D$)9#;2F>9D@"*7@-1E:93,7;?*61?,1=A0=2=453B$.
@r1780
AAAACTGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTG
+
/0*7B30?A/4"C0C#B+D?'++@A%B!=?;9..7H/A$(#5$C;GF3C-2<47B=ED&8H4&+?@:0D;)<@7A>&C24-
@r1781
GCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGT
+
!;F:)E-*$3&+#%(:(B>;160.G<6F>;=(/F+&=(A(>C*&.A));
@r1782
AAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATCCCTGGAATTNATCACATTCCCCTGGTTCAGAGCTGTACGTGGANACCATGAGCAAATGATGATTGATGGCTTATCAGAGNGTGGCAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAA
+
"?,#H<>(<!3C9=-?((*-G>H=@#%F6/E,B.G4E-=+0AA3".2G@>.@;*%@E28':*@:?4!FFF#-5+:94C<-@%.)2.D:;/.63#!C>:H@?..,;:E2-<1!"5*8&@/*!C"F:60.%:02H%A72"GC1(.@'$-A#6)<3EG7$4<&(0.'A0(3-DGHAA'#8BDFC3/*5G:F015C2EC(D*=C&1:A620*87$(;#2+=547$751H.B83F4B9
@r1783
TATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAANATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTNAAAAACCATGGGAAAGAA
+
++"*&&$#"&))&'#&$!(+!$(&$)(&#&+(!%"!$$#&)*))$(!!(*&!#$&&&'&!*)*%+#!"&"!'&&"+#''()$**&##+%%%*$+""''"!&'(*#!%*#)&&#"$%((++()%&+*)#+(**("++$%$((#!*#(%('+()'+%
@r1784
CGACATGGAAAAAGGCCTGTCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTT
+
&*2$.29:+*C1/&%53@%F!;1+!C80/,B(239&#B+8?(9GE0F1!$8$G5FHD-7C;4:G9<6)637.),A"-,)>9/H78?/A=)-2@6C@G7')A6<5
@r1785
AGGNTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCGAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTNTGT
+
B=A)#C0C"*<A=1+87(2>4A/26>%A!2B1*8D!!0(A)3.@3=H";?G$98=&>&3'A!>ED3=)F7%?'>;1@=3<=?H#8:D'7F&E%E%:?H?,$5$7F*AGH7H1'=17C>@E7)@?D6H8*
@r1786
TTNANAATCGTTNNTGGCTGAACTCCTGAAATAGCTNTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTA
+
!#!&!(&!*&(###(+#$!"(#('"!+*$&++"*$$(*('!)(!'+(+""(()'$*((&"&+$)'!$''""')+$$!&')((!$!!*!!)*&
@r1787
GTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGNAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGC
+
*+*$$)'(%"!&&&!)($'+'$'!"#&$'(&#*!)**"%)!*%$*%&#'(&(#**'$%'!$%+"&%&'&++)"!!)!$#'''##!)%#&%&'$$"'%)+&!*'##$!'!%+%(%*($$&*$
@r1788
GCTTAATATTCTATATTGTTGTTCTTTCTGCNAAAAAGTGGGGAAGTGAGTAATGAAATTATTNCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACNTTCNAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACNAGNTAAAACACCTAAN
+
?./(@A62EF0':8><%EH>..-3')B-#168(B%"';!<8B4CA%7C$A1;D;<C=B+,(0</4!'F"0D!)HC*D.B&%*.>9D&,:3=B-),%$4@1'?G"=FAF+H4;39B9A,E@DB?>/&=>!>7!=67$!?:2F6E>??(H9"566!C),G#;-EE:)B&5+F%2F.)?CD),"H#.?2B9<C4'*B<>?$$>"DE*"32H-1>FG#G+A.:B$2:A(#63%1E6@.&HG%;@0-0*.=*>4<5;=<+6"7-A6E,GE!?0:#F:!:2HB!)98-'7FDE8:#.6+GF>,'.D%,(.!+A=#9A9!<==*):4!87$:<$G3A8/2A;1*F36)
@r1789
AGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCNGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAANGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGAT
+
5%8*$-'$C-=&7D&',1&'=%@>G*718F7@7:D1%)2#)D-?.1(F9=9#*%<+)D>;D7<4"?467E>$F4'38#/0<"5&,'6C3=#AF3&-:G'.?#:/A%+:7AC9;1>F@?9H.A&7?*0#:8F70#*:@D)=3#A2,)@=H=+<1G4$382A%6%F;,#:1!0&$?$CG<<46!95,2:%&*6>,'*+$,8!!#G-(>86>;D=%>?$<97-F30!!4,&2!6-B8CB'$?&4H#F<46'GHDH.?DHB-HH#G@
@r1790
GGCGGAGAGCTATTTACTGATTACTCCGATCACCCTNGCAAACTTGTCTCGCTAAACCCAA
+
G*8H;GFC5,=H1(GBGBA?,>,/1-B3<8/2/))359*$<'6?D!(+)3A&A6D!+6BB%
@r1791
GACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGNACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGNG
+
9*56@61B-/D*<F.9'83&.<7!@1.%962-)D-2(3A'G,"86"7@7B>A7<=D7!,+"D1,>$4:=,F%#)1#@B/+)(H@&D0"G<;C6-H?C0/6E22F=!;%3:?--B5
@r1792
CGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTATAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTT
+
46,;>1&@5=8$%'-H,3/9F)1,.08...@4):3DC"HE@;4>E/@-3+0?5!(7/!(8?:!--3G'5G(FGA<+?#&;#!'H',E+)%;2%6DEGH(HD6,55F=/B4&$3B*3)7!@B%>1;1GH0G'C)"0854,2&)33@"6((5@6(*>B(,E&<.0>,!96*,=F<-8#HE:7?(),@1!'E)0$%2<@,>>E,%"4;"9@()B4,B($>:0>8*+@A(<H=1A@(<*B$(-(%/,5><D3C9?&614AG!FF?5:;7)&.D".,B*'7&#1"/1
@r1793
TTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTNTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTC
+
F9>F0@(21E--$*>1)6<:96#2&#5?C6=85GC-,E,'=$F1=5(2$-41,D5'A'<(>771?E5#+;*0$D<*7D#FH).&&B,&G!<?8G<.,946"F+(G6/60C?0(-A?7+"
@r1794
ATCCGTGGCTCCACGCCAAAAGTNAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGNGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAA
+
-F-*&G#3GF<32:13%.",.2C;39CC$55!8CE142<$FG2-2>'.47.3EE9%!D7;(4(.#/D-F#62&1$D3A'.A<+9G/4,"1=0'"BH&."2,3>1?%+(H7E?"B2%5$HH%%D
@r1795
GNGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCNTAGGAAGGTCANTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGG
+
)&/%--71=H#!B!'CAA=.3'DE)7:D,97-E@B&-.?"G$A#"5<C(,5D2=/C??6A5$=&:#*>8C$6B<%"..3+@?"3;H:$>85919?1;+70=BC%@/6$=%7(/?;.9<4$0%:445/>4F2=&?)45/EFD?4@>A)-E3#.;G
@r1796
ATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCAC
+
DE1.*"/;E%7&/")='F6-#8*A?'(!75G9!=@):62<A@7("$8;7H+:9++;HH9?C.'G<C)98:A$>%4H66.;B#F$BD<15DBAD>2+"
@r1797
ATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCC
+
=GCC80-B>.>5#166*C:CHB0:B5$1:0='6+!7+A5?4>;8-'%DF!#E$-'C7H)654E*G,!)432'C))E8D$&D+8D>10*H80"<G)+<)&7?A(>;.BC(*39(3:"@0:43A5(?:+,;;3,'
@r1798
GGCTGCTGNGCATTTTTGTCCTGNTGAGTCTGCTGCTCAGCCTTNTTTCGGGCGGCTTCAAGC
+
$?.7%;=5.15F2G./9=8/"<F3H5!%)")%=B:&(9.F'&EF?B/>5=DA-0)1<+4"9*"
@r1799
GATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCG
+
*<706/=)37F="3D3:2'0@&25)="3FHG1'25B:<'2;!$/B8*2.$%+@9C2$"!&1<'3,G,5-
@r1800
ACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGC
+
A#9@/D#03C&H@;$6$G%8GE&$1??G3B#765%-*F*/3:0
@r1801
NATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGNCAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCANCCTATCAAAATGGAGAGTTTTATGACTAAAANACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAANGCAGC
+
!*#*"+'(!!")"*+)#(!!"!'*&&')&))!!+&##!+"#**&$'#(%''%%*('!))(&$#*"'!$(&!)&%"((!'&%%&*+($&*&+*+*&&)$&$()$$&**#*'(&+#%+)%"'&&)%(&+#%()))!+''#'*&(%*&'*$!)+$$!%#+$$!')!%+!'"#$$))"*$!*+%)&$##"+(*%'+%('&#&('%&#*+"+%#%*$!&&($(*(+$
@r1802
AACNGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCNCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCNCACTGAAACTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGAT
+
)$%"+"$$((*'+&)**($)##'!)!)(())!#()+#(+!#"$")+%(%(")*&#"+(!&!+"))#*))!+#*&##*!#'&$$"%(#"&'($*)($$'&("#))&+%*%#&!$#!)'"*"())#$)%$")#!+"#*+&&)($+)+(&(!+&!&#&%#+)%#*)$+&#)#'&$!%**#'(&%)%#&+)+$*&*!'&))(%()&#"$*$#%"$&!*
@r1803
ACGGNCACGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGNGAACTTAGGTGTTNTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGAAAATGANCAGAGATGANGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAA
+
6$,)=F,-&"CH3,E0)>)3,'#!>A&*63D-C!/A*72C3@:F8B</$"9**9,.)5=E?*HCB%52:&9&645<-;<51=D(;3B5F)D0:50D5;D#-+H"H"4+=3&27)'E6@2!$:396-:CD<!%4EA$GE27+,3C,52;2:2<C)'.'36G=7$?&1A)/H2'"+#-2")#42932&&$H#G/*4B(;0D.5$)(*C@$89.C1B/&'=*#/97A<"<GC;07F&>8;H368E(-'<7C<$2"#(""44:<B./%FA'676,</=FC77GC+,D*'5#/&1;7HB3B&D4-7E4%0C/(3#&B/@G-0F&+GA3+!HG<:$F#@<1).!;9
@r1804
ATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACAT
+
H&B.-G%80>=-ED@?D@F,)*-5E$0D<0E>)=HA'F=5$!,!E1/&F3,1H7.A-42?
@r1805
ATGTTGCCTGCCCGCATTGCGGGGAGGACCAGTATCTTAAATTTGGCGACA
+
12E9+56G'G>!2H9'.D=.E%F-D#1=5#.;8'$:$?*-(5/+@EE*,C3
@r1806
AAGATTAGTAGATGTCGTTGGCGAAAAGTNATTANTTTTATTCGATGTACCAGAGGTTCATCAGCA
+
@@BC11,1/*7>B&(15'<$)B.DH.$2E;7H1D$30@@3A-*(9..:.>9=E$@6>E;%EH@5"F
@r1807
CGACCGCTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTNGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCNGAGAGATTGATGTATGAGCAGAGT
+
H)8G%B1.E>.6)#8AD&AG?8/;+56>C'D;27C,B+<("#<:GA=>!3'.(6"F:1-&:3*C,D*C;8*&D48!-B9053-=)=2<>+)(6H86<D'"A>/C>!E"B(#1#=%#-%336'"/=7;/B,#;('
@r1808
GGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCNGGAGACAGCGGCGAAAGACCCGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGNGCACCCATGGCTGCATTCAGGATGCGGACG
+
.2'0!%8516E=G;<=&8<&4B+3D).3!;,>F?-<*@.0B%4/'/!)$B2E4C)%C"B"><80GA-)5!-FAG@48&*>)7AA+=/)7A,3A,;E$@9-$*=3$2?@F492=>:B=6'&*)*.A!.<FB#%7<4;93'*0.CE(#8B#D?C6%/)0/3(><H;:F)?F>-/&=!@D%A<(1"B:(%@,,*('0<C;D@(34-7.!@<<#!#B+?/(?5.>,99H(A@'9C"G#&79/1((<2)"6B(%4@;?$EA'9?9D:4>())&C1"-'><378D79'F-HC=-+7,F!,'=
@r1809
TGACACTTCAGGAGTGGAACNCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGNTCCTCGAATCAGCGGN
+
8!?9;'E%68/5E'/%0?'2*='&5!GE*<:>2@%4A)CF<#52E-<+@%%ABHG'!H2)B5+<A;%>H-.4;F./1=9G/:G!&3FD)/-G3%-:96;9-.&0A<8:C4&=<7#-0C:?"3.16H2@7F<F-)!2
@r1810
TCCATGCGCTGGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAG
+
2=&1A:('36:+8D1?E<*&2.%C92*4>A>6</>'6&B>/7A!3$?/=$1B@(;5'G6/
@r1811
NGCTNTGAGANCCTTTTGCTGGNTCAGGTTCTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATNGAAAANATCCCTTTGGGATTCTT
+
*&*"$*'!%$!'*+(%"(+++!$+!*!$#"*$!&%(#%$%"(%%&#&*"%($*%#"*#*(((')'*%%)'!+")'&&)%(!'&*$"()'#)#$%'+*+!!&+$+))$++#
@r1812
CACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACA
+
+&&(#%+&$(('"$!(&)()$(!"*'!$##)+()&'"!)$)**!%!#+*(%(&#!+
@r1813
GTTANNNTCTTNAGNCANACCAGTNCGCGGAGGTCANAAAGNCTCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCT
+
))&&%!#%"*$)(#($"!(#"*"(#&)*%(%()#$'"#'*%&+#!#%%$!$(+((*"!&"%&(%&$*!!%("#&$&$+*!"!$)()
@r1814
CAGTGACTGCTCAAATACGGAGTAACCGTTATCCGTATCCTGAGCCGTCTG
+
:,7,6)>B#890$FH9-#;$<$'"DG4709&#2#*?D#=B70@--E3C:/A
@r1815
TAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTT
+
<F/G0;5-5(*FF!:3D@7(/G)A;9>B"B0:%';"/**>19+(,A/H4A?=>:&C888!-9>*H=@C#G87/G-E$74+C"?35==F0E-62%3;%>F(+?:58+"&$<-2>8!<F+8#B
@r1816
NTATCGCAGTCCGCGTCACCAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGATGAAAAGGGCCACGGTCAA
+
):-0F:$)2(E'8*@7F501!E8/)#-FF:?:B(F82=84D,"F=:$9%>*=&!HGB>(/8419F,$;$GD?2<9G08@E'6<?7H.(.5))7
@r1817
AGAGGTCANTNNGGCCNAGCTGCTTGCGGTAGGCATCCCACNAACGG
+
&*&'%()#&)""(%((+%)&#(#(!!#)%)+$!&!#+*&%'!"#%)$
@r1818
GGAGTTCTGGCTTTCGGTGCNAGCATCTGCGCCACACCNCCGAGCACCATA
+
G=H6$=!$<"#H-#%#+9E7)3&FB2D1G@+0-%*E%&..>F@,.<,F(*$
@r1819
CAACGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCNGTTNACCGCCCTATTCTCTCGATGAATCGCAAACCGAAATCACNAGTAGAANGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAANCAACCTGCAACGTATTGAGCGCAAGANTCAGCACACAAGGTACAGCAAGCCTGGAGAACGCGGCAGTTAACATGCAGNGGACGCCAGAAAATTA
+
"'%$*&(''(+*#"!("+')*#(%''!%$*#(("+%)$**"$$&%(+%'++#&*++)*+('$!%!+&+%'"*"%()&(+())#&#))+$!%'()#$$%$('#*#%$!"!#&+(+##"$")$+)"'%!")&!&!#*""+#)&!$*#!$'#"(*$#*%+&&#"+$$))%(&()'")#$"#)!$#)&)!%'(("!&&$$)'&"($*$&!'$+*#*"''$!%)*!'"++$+'!(*"$+((++%(%'&)'%#!*("#
@r1820
GAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCT
+
?<'2'38%F*CE1A73D('57C:F"=D%/H74#,%)D@A((AA@@8,,D5$4-?&5@0?24E86(<':=8H6&D7!#?$/<-8AG7:2,@.H%E33'>"@/*,G(),%F/H'
@r1821
GCCCGCATGTTCTGATACAGGTTGGTCACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCNGACGTTTGGCANTCCG
+
6D@$C%0736F9(AGE.&)/"74/CF$@+,;,+E92'C'"$A*H)8H?&H58=1%<FA@:.@-C.H+';?;43E4,1@(0!%!G'F5,:H>FG///(>;-5C*',*=*6$9/&&.A"-<2E.1>5H5/#**"+>C/+#/9C='4
@r1822
NAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAANTAGGCATAAACACCCAGCAGCATTTTGG
+
"$2:(9;'/?'<.F5%#%C<>,$B&=<A3>H/F'."@(/F*C*--,'"C+0.4+16295EH@'+FG6?
@r1823
GCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTG
+
9H1>C4"E&8E9>51@=#.%AAB*<7/61FD/516GD!2B"":$G=';'2AC!9.
@r1824
CATTTATTATTCAAAAAAACAAAACCCAGATTATAGNATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTAC
+
E#+">AF=98*C1#>21$0D),G4F%=-)!<'<-*%'D@/F2C>-#8<<F9H7E&2<6)<3D;</1!%@+)"B?:,:G521<<?F?)1$1,30$B2&8:5<3D<6=./6$!"&8<'!=('+5;1G2$-D25-7:8C32>7'H%+G>:)D3'G$3B$@8-##-:AH<(7%
@r1825
AAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTNAACATTCCGNTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCG
+
4>;G'AD4F'',=-(6;;;*'B15>G>6(2E%'?)9-A2H/"+*1BA6<1#<6C43792G5?,>F,7>B>("1?#@@*/90C#E1231*(1EH@#BB+%C'$/7?-C@F*;F;F31">BB2B-B;FC(+3
@r1826
GTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAAC
+
H)+E2,D7<@1E84C>::D&"H;:G0.C4EH'<-E;@?*-.03%;7<'HF*(C$!-'B?5@<=6?)
@r1827
NNAGANNNGTNACGNCNGTNANTACCNCTNCGGNTNACTAGNNCANT
+
$$"$$!!$!!"!!#"$""#!$$$"####""!#"!""$$""""#"""$
@r1828
ANNCCTNTNGNCCCNACTANGCNNTTNNNGNNNATNTANTANACACAAGCCNNNNNANGNNCNNNANCAGCAANNANTCGNAANANTNGTNNNNNACNCCGNCNANCTGNTNGGNTNTANCGGNNNNNNNTNAGANNNNNTCGTNNNANATNANNNCANNNNNNNTTTTAANANNTTCNN
+
$#"$$!$#!!#$$$"!$$"!!#"!$$#!$$"""$$!"$!##!!$"#$$$$!!"#$!#!"$$#!!"$$!$"$$"""!$$$#!$$$!"!!$$#!$"!#"!#$#!$"#!!""!#"""""#!#!$$#"$$!!!!"##$!""!"!!""!##$!"###$!#""$!$!""#!$"#""""$"#$""#!
@r1829
ACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATNGTTA
+
<)>D8C?6)&1%$"+!B14E!1$&@'."2635A+0G>'1:1<&@+CBD:FCF8E%C<(?,@D#:!1+F!B07.#/%1@0?=(-CB7%(4.F(E/E=D;
@r1830
NTTTGCGCANAGTGNTGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGT
+
'$'!'*)!&$$!*$"(#+"#""&$++)!+$(!#%!)#''))"#'!$')!')+"'++&*(#(+&((%#+'!#$$$'')$)"!(")
@r1831
NTGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGAC
+
#++'&$)''*&!"&&!""%*())%"$$('"#*#("(++!!%*#$'%!)%'!*#&&$)&+"*"##*&+*$(+$!$"$!+$''*)&
@r1832
GGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCA
+
%4?-1E3E3>?285-A*?F;"7:.B4&>988+./A!@=1DA'FFD7H5=@@F;B38A/=-:E6;*-<7#@:A7;/>060(*B2'H;7#&B
@r1833
NAAACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAAATGGATGCCTT
+
")+#)#&''(&"!+*'&+&&*$)#"*)+)*+))&##%*()(*!#$$+$$+%#"
@r1834
TTTTGAGGGATGCACCATTCTGAGATGTTTTTAGTTGGTCCAAACATGCCGCCTTGNTGCTTGATAATATTCA
+
6#$#).4D32&#+.F$$.;CE@+8"03HC**.?;3=G8:+?6!7)9!0'<*04/:EG/,05;75A)1/%0$71
@r1835
NCGTTGAATGGGCGGATGCTAATTNCTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCG
+
&#A,<C-")24?@4"F:$+8%D0>E0#<C>8,+@7:;+EF!074GG194-1#(&*G>1AB4H
@r1836
CTGTTGCCCCTAAGACATTTAATATATCGCCAAATACAGG
+
G3(B<2!?!3E+CD!:-)$:DD'@7<7&8(:0>@@6A"9(
@r1837
TCGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGG
+
!;<38/:0G*$:6;CD'41E#!+"(9#<&D0&FAH<<9G5<
@r1838
ACNACCTTAACCGCNTTTGGCGATAAGTCAATATCATACCGTTAATATGTTGCCATCCG
+
*$"'+*")!%$%$&'(#*#!')&*%#)*%+$""!&!'!((")%"($!)%!")+(#+!!(
@r1839
AAGAGGATCANAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACNCCCTAACCTTTATATAAGAAACAATGGATATT
+
:-3"B!2>0#=747F0!169F"-0.A23,8$E.F,/;6B461;#AB:;)D=/,95=A;,26H&63(.)<933/!617:&#$6;
@r1840
TTGTAAAANATTACGCTTGTGAAAATGCTGAATTTCGCNTCGTCTTCACA
+
)#(**%))"%*++*"+##)%($*%+'**$#'"!+#)&"%))!*))("'+!
@r1841
GAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTNAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATT
+
@H/?#4D0:="CE#(>H1+-3!$8<G>*H"6"&3B#&D!.*=8<@'(%,')<'EE2F<246,/*B27*%1G%8.?3%.86H5*2,,'83;2);B!1;0$C0E'>+;95G>!H;;B&=#9#6+3.:6)*(C2@/H3,F?0:B!,)
@r1842
NCNNTNCGNNTTGCCCATTTATCGACANATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGC
+
!!$"%%($$!+$%!$)((!'%+$*%'&"%!#'!#*!$+!&""+*#("%!+)"'(++"#*")*&++))!('#%"%+"$&(#'*!&'+(('(('#$**')#'+#!
@r1843
GGTGNGTTTTTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCA
+
#!)'$(((%")&#(!+'$)$!#""!++$&""%'+%'(')#'#("""$&*!$&$&(**&!"))'"'(#+$!#&++%#!'"'
@r1844
CAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAATCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCAT
+
E&%"(C3!*)&!F)H+':B##7CG7?GC7.HA>'58C*'@F*/H/02"E;7..8'6/$(/E=?)3.0*?H4+A2&BH,4E6@73..,+E=G8+D6AGH@E#0AD#D;,*>+"(@!H8
@r1845
NAAAGTCACCAATGTGGGANGTCCGTCGATGGCAGAAGATCACAGCACGGTAA
+
!'+!!"!!'(++&!*!+*#+""&%$(!%%*&$!*'#%$$%#$)+$#"#%*"'$
@r1846
TAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGANGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCT
+
=CBF2$/16$8C+(A#-'H.%7D#7*AG?'(F4E8<&DA5"($;BG<<*-9#1=B@EHAFG'3F1#C8$>2.'%,?(4/@A-$'625
@r1847
ATCGGAAATGTTAAAATTGGTTTTGTATGTCAAAAAGAAGAAGTAAGCACTTA
+
,A6>4",9'A@5:5)#*#;@H*5<#;$EH#'6C,,$*4A6)>D'<:!60=",;
@r1848
ACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGAGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGNTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCC
+
?01;,H=)963A":D&G>/-4@?,."/)'AG(8**#<F/#+0&;9#3,,&-24(F*26C'?)#?#2$*+6<6"4%18.*!;8<D&E6;6"29;67)54A%86/B27.,45H,B*:!'-HBG.#H%-71);(B?#+H9"HH:;,&B&?#!#-;2E4AC;DF'*B<"AH,2B.3GC+1?715#G>$2-1B2E1$?=2'7.A/(17&8+GBB5$(B5(0#7>!982@>,#$0.A2EF
@r1849
NNGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAANAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTA
+
!/0/'<D>1.=E"*="?'@+>"1-(.(2E>G5G0?AA(!<.)8>*(8<7&+@2D>72+%EH*<<*,.%=A4>/D3<.-B=@5>2:D3,E,#A5G/'?!1"%#F>>-&D<$/1&031'134!0B$99,DGE"'*A50.</*/?<7/!0#%C(D%$"65+*#"-<E8E::C)<@-22D3"5-)-"73@38&765'5%D4F/#0,60><,&!B">4%64*,A'/G"A'F--B#3,**>>!(E>+,3?29A443"8CB+-%E1:&''&#5?1EG8G3%23?11)11F67G3F04!+B#7F3-B4,<;A<B29?!74458AE:BD:%'
@r1850
GATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACC
+
4B9?%1;%'2A8$GH$754.G&D0H69:),37D.HA<!911)!#<>24AG).GG'56<<,.(5H@=)B/8317-?&8;+C+C//C((C!44F!!<!AC<*2B7":0#?4&>%7
@r1851
NTGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGGCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGNGTGATTTGCCGTGGTGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCT
+
$!1F<##"-D!(-B,4E2A=>.9C@%;,H@&E;/:>9:),93)@E",5>+8'=)D:"42:>:?*-;<FG/0?9724:>%+FF=G%@A.$F3/C@,;H8BA4.327$#H?7:9<#:>6A;EB9578>(17+6>;:)>-1%?B04;F>+.1H27D2;%)+!EHF+2)4<?1#2?7G=5&;7<G+!"E;+='.$,F0"@)29,=#85.816C4B*:#?#A(>2%)."326>2(.(1A;8B3,<@-(C1:#)4$?#1B
@r1852
AAATCAATAATCAACGTNAGGCGTTCCTCGATATGCTGGCATGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCNGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATNACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAA
+
1@B'8#B!6E"6*80"87H!03.,=)"47F%#%@G(4(0,A91%3<"0/G++G:7!<+9;.BFDD3H@,HAB2F8@D%H7D6+(-26.8'8%:DF1!>?C7A?H:;!%,,%15&%:/C9AAC8B,2;(*@'FH4#',F<-F'<<B98EBD1)GC6:/*+'2C*1->!/&3>*B
@r1853
TATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCT
+
2F=+*$=6?*#&-8-72,;;%(F.E(;"2*15.>EF/,%'B%(#FA:-/C;7H@=C@:=;D4#%')F1'GBA6&8FC=%C8H:
@r1854
CGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACTAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGNCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACT
+
F99E/H.G=H>2/#E0+3":4;=?FDG<G:?00EDDDH;B-#+2>2GE/H2G4%@CC'.*"F0.C#*G:,&%@:=9@!B5*%'5$G0$%@:4(7!+BDA(H%H8&'>-GH=)87182005;#GBFF.E,+*BA>'-<?2:?7!:>9(D/1$)?C/7'1>>"1<CA,))561C!,FF,G93,1@6:B;AE@A1A43G<?!/<*7@/C846B$3&<8;*$++6A0<%2C5+F1@47%%,B81#$A"2@19&765CCA
@r1855
AGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGAGCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATNCCGGGAATGGTTTCACCCTNCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGAGAGCACTCGAACGACGA
+
;>+(F5<D,'=&:0$+7/A2/3G5A<2,?D0;G2<?!869&+H4F+?5&C+"9$6@87A*&8&4F9$#DC7@G23@!9H>>5(>G@B=.4@#850,CA$HC8",#5;HB(=#?+)"/")&7H('%;F?%(-'"G*)&5%)7*.F664&&4&FA4A+2B)67(00>%H.:"7)5C5H2G*&)E.9/!&=*D5:(;4)"
@r1856
TGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATNTCAAAGGTTNGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGAC
+
2+1*3&?$!0;8HB-'BC/$"@93?12&E>)E#!;@<G/*!)*:=A+9C6B-';)$!%,BD5G5(-,56<(/:4*#<<06C@"9G@>2,;,B:(:G=?&;+,?.3>$E@C881B7+3%B,9%H2/0=)H=>4!+=@3.14H'@G.=DB!5D5FD76$9,3>(0;>7.+HG/<EC9.,:)4#@417;4$FC+3G95=)AFH!)"3"CC9/4D3G$6HF=#AH66;D1>>4)H=(>HD#6!A(1B5@)E.4,=;?55B=1&31.$B'CA,
@r1857
CTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCAAGCGAGGTGTTTACGAAGG
+
3/*,"100&GGD*<::#F-4F,(*!H#H%"=/B2/+08;3*;.G40&0'E'8+G%&))))2*)"8A'<6A6&#-%AA-8,93.6F%
@r1858
AGAAAGAGTGCGCAANACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTTCGTGA
+
7;28,A76&$;062).#+@-2C'CF>#,0H+D61,AA7<+1*#BE2/"9*<F7AA.;.:+C
@r1859
AGCNCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCA
+
):,6C<D;7G6#,E=(AE71')C=#E<89)'%D%-7.?6H8'AA+"&"6<FFB+
@r1860
ACGACATACATTNCAAGGAGTTTATAAATGNGTATCAATGAGTTAGAGTCTGAG
+
;-)%-A*$453;F;(C7F!9*51=B-HB&%=7C.DHF?H%@B<-'A01A5:=-0
@r1861
ATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAANATGGC
+
3-+,97@/./HH0#A)(1A55:4G$$40F'B%8)21"%GA;7@(=E-6/73)B<-%C&'851":-A1;;&6,0%A*)G0B#+80.A@%5<BG>>?2/%+'E:3*)$,A%=>B7D+?GD/403
@r1862
GGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACGGAGCCTTCAATTCGCTTGTNACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAT
+
3*2A:0+B3%):*".9-A)2+9:;?G'",*#"BF/=2H#!0<9*F-3"/A.@,!)+B+'1&5)!"3B58.2CE<%$%'@&HF@.%C6/-B'66%@#(/@'7&79H7)CG7*48+5B#7DG3?
@r1863
GNTGACTGGTGGCGTAACGGCCAGAATCTCTATNTGGATAATCTGGANGCGACGGGGCTGTATCAGGTGCCGTTGTC
+
.@B21>$??7?8%3D6>=A?>26G7B.5$FE:+75%<:=&B/*(&!B$*>H:1<2;:-(<!>E0.$G'->312"G)=
@r1864
CTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTAT
+
+)'$+#%#&!#*(*%'$+$$"!(+$'+&&"#%+"#!+$('(+(#%)*)&")(()%(
@r1865
CTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACNANCGTGACA
+
/3")(GE)&.'5FA(3@G&:3-79?0@<)1%&"76<9;%+A),,7&<ABD(<39,.,";:6/(6'>H-10G8"
@r1866
GCGTTTACGGCTTGTTGGGCTTGTTTAATNCAGTAACTGCGGGGCTTTAAGGC
+
@55*A'+12),+3.58$F:D'D'.:*D,-4."B,(4,+?-@$=@1@C>F04"2
@r1867
AGCGGTTCCCCCAGGCACTGCGGNCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTNACCACGCGGCGAACGATGGCCTCTNCCAGC
+
!)*!+(#(*+&&#(#*"#$)((#%#$""!)#*"+!$%+!$$#+*#"!"(&%$$(&"%)&%+#""$""$&+)#!"&)*%%%(('+*##'&()'
@r1868
CATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCG
+
85@+2'6+*40H.<)H=C;62(542-404<=@E.?FG*5+;2(5@C63*<()!9C7
@r1869
GTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATA
+
6$:H4"H*9&96/G&H@$!)@ED,@@#5?7A,E:%=,>3)<"3B/
@r1870
ATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAGGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTANAAACGCTGATGGAAGCGTTTNTGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAA
+
,B:;&/F6H*@&G4,40'2>#DD;(7/-D*E4$7241:C298D80)@($)CE;#0$?06+38392$0C=8&1BC,G49H*$=&<EE;??C/)A;2(&<HD=.?,<H/5,C89#)C#;1==9@F:E5@>$AHD)E243%(>)A56BE-)8',07D&E6A&*
@r1871
TGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTNGGTGAAAGCATTGACTACTATGTTAATCTTAGCAAATTAAGCGATGGTTTTAAACATAACC
+
+"146#6@#1>FC-=!+F!)!*/H$5%&G(E'F*!-/#/%0;/6D'5)"EH%(.$3--96@?D0""?-5/D559,28*#0<%'<%,.,3/@C44$=?+-B5"7(.=8'%:F.D539!<8A9*2C%H&+H1)90D:7E'*$8"6*.!D=F6"(B)>:2*47D)72DG19)>!-A99;!4(=91DB<FD,AC##>BB/D
@r1872
TGCGTCGCTGCCANTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCNGTCGCCGCAGTAAATTGCGGTGTGATTCGGCA
+
+2HFH/@+431A*"A=936+?=51,!3(G@@(71//,2050$=87?A69&&2=:8()3B84%"7EFF(A&&:G@!%6'71;!(;=72D5GF4<3"$'6-?-*#"/
@r1873
ACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGANAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCC
+
/=*%).?+E#>@=F+2H1/CB:/0+1;+7<71%@/6D95<1-C:00?/$$$C<:27F>6H%GG-@+3G*%2A1/=<';9,3G!>86,<9))<4A&#A6GG$'69-9%$!H<*-$5-=E/
@r1874
AAATTCAAGCGAAATAATTCAGGGTCAAAATATGTNTCAATGCAGCATTTGAGCAAGGGCGATAAATCTTTAAGTCTTC
+
%63>'%"?*6#A<+HH8*@G6+?::830;84'/43E"D-<AC6"+=D1-9E.(+5@.=.,*2H4+"0/;713&;/"F37
@r1875
GATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGATATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGC
+
H'0C$-86;!>!#*.B(4>#5$01->!E<92%&2)@?#(#F-E8"'AG&<5(/0"=B0*1>D",C>9&2G'F.&?A8<;(*C7+>AC/,2::C.=#!03%>B)8'1=&8$8#%F0D(&*@H;1.#),@)<<-A7<D-"38>-H<B//:)@%+7G00.'3$1H+1E/20&0E"4"938BAD'B'EAG@3>'02$&06&-0#G%&3!F@:H.F"1'</&"
@r1876
TATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGC
+
8&@G%=15;<7"F&G*C5<1H;!89:A#%@5B+4/;C:,$>'?E)H;A)C:=%E#6!
@r1877
TGTACNGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTT
+
)G(1,1.5$9@2(.$*-84,<";%!4D(?>!"*$?-'BH?#5/,BF"/.()4>?E#EG)>:0F4?(EB.C:1(5C6G;'@DG3G,C78:68.--7C)&D,$7H
@r1878
GAGTGGCAGCGATATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCANGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCA
+
)CH6;3)>6@*A1+F:+*!6C>*+=D:>@H'$9H;%86>):3;1"15,&@%+B8@/!A(17@&30?H,!),#G505:?1>D$F3F;09"(+8#)HC982)'*%6!C;$$(1.5#0D-)"#3+D;&&"@:>4"+G)!+@F7-$/9"D:>GF/(.$:%F2,H9(<-C4$A9@(#74A-0$/D@/1)/"&;0<"*54$D@A/19:6"6???!G+$:.&)2;G@'8<??/"<44;0.7;,"=5"'"6'&28C6D?F'!F$):/(')!2?&
@r1879
GAAGGCCGCATATGAGCTTGTCCATATGACTGCGAGAATTAACCNTGGTGAGGCGATCCCTGAACAAGTAAAACAACTTCCTGTCATGCGCGGTAGACCTCTAAATCGTGCACAGGCGCTGGCGAAGNTCGCAGAAATCAAAGCTANGTTCGGACTGAAAGGAGNAAGTGTATGACGGGCAAAGGGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAANAGTAACCAGCANAAATCAGGCCGCGGCT
+
#556C7GE>G@:,4CA$.+0*F3',5/;),<&0@43#:%5.9;20!%:2&HE<4:10$:*G7C9"%AH>$!#-1(C85*7$E)A8@H:D/6H899$:$>='9>>7D+)=,0F.F%C9,>'(+9)6;%-,F4G<"1/1,")$$H8%:2!9&12%?59&;H$;C#4*FB<>0A:24%24GA4/&8.@$>$54=<'F;5;4(F=.HAG*G-++*)8%BH9B53:"6:%CG$)%78'C#.8E30!6<H#+?=DG,B$E8/6G-DD#3/4=/5$)E8CE;,+F(E,%CB>
@r1880
TGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTT
+
*+6F2;7D)05><=@B.9&0;*!AD7CFG<>ED:3@>3=#>D=E/91-C94%A!H
@r1881
ACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCA
+
$=,B)'G*'37&."B>),7=8(!D#13<>FD4,H-C9>7"=D0.30,+/"E#,3>;6
@r1882
NANNNANANCGAACCCANCGANGAACTGTCTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCANGTACATCGCAAAGTCTCCGCAATTACACGCANGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCNA
+
$)&&"%&#+#!''%''#!&#*$*&$"&('$"*$"#&+!&!'*#"$&(#)$*"#(+%&%#*$"%+!)")(()($(%'$$"*++&*")$#$!!!$&'&"+!&%&!%!%!(+'+'"!&)+"'$')#*!(*!$)'+#%$&#'&!+$'+(*'$#("*&&#+$
@r1883
NNGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAA
+
&!A1/4H<CF;B8*8E&$C/!4)&47#=%+4A1!$@AFB;4C'=)B5#<-'=?$:>@@)2D05D8:-G6<9>$E'C&8;',
@r1884
GCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTT
+
7A-");)!=$&G0)'<+*"3+)-H12(323'4*$1HG6.C?%4-*H4956
@r1885
GGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTAT
+
#4<7?E<>$H,@<0:C>28/8!6<<%3H*8!:(@<@:://85CA&;?!"'-C03-B7267E%
@r1886
CATTCCCCGCGGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACNACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAAC
+
"C7;#'@;/5$94%9+8;#(51/*---'@:='D3!.-#H),5"C3<8$,&1./66=*$+E!=:F2/7@78!3-(C:51:@'02=&&8'(9!0&&(*4")/$5?-"-AC=-(:'7-):&+:2/!0C-#@D+0C;B8E?$F5:>8@B64=C5'/1E4H5:"3#&B.>"B7H(/@E?;04:.$A7FG<.F&FB9<96::5&)6(D=0D>&6H*+G!D4=;BDH:=4#;
@r1887
TGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTA
+
1%/.3?H#1-F,2A01$$>&=5D%)>3:"A-(H'6*4CF@@&AA0:!H(D:EG63CFA>&61;'E*1$:+74DF
@r1888
AAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATNTCGATACCGGCGCAGTGTTCTGCGGAAACCTAACANTGANTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGG
+
)=)2&@&"/C/<.01;@./-8CH9:.H"'+9=A#-35*F+>*,A!"@)2-&,82)'E<@,:%4G<)51:5(=?CD@7?0!?C1'"$%D;%B*$;35&$A1>03.C01.85!F31HHF7<B-G>=HD$)DB<+G?3>C'D-.4#E)!)#B4762@1&'E+-=BF5DC/<,&2*2F7G?%+2@;"H*(',:/GHA<4#-45BC'"*9>,0B/43>428
@r1889
NTCNCNANTTGANCNTTANTNTATNTGGCNGNCTGNNCCTGNACNCTNCCNNNATCNGGTNNGCCCNTACTGANNCNNANNNNTNGGATNCGNNANGNNGGTNNNNGANNNAGNNNN
+
!"#$!$$#$$$#"$!#"$"!!""$#"!"$!"#$"$"$!!!$!$"$#!$""!!!$$!!#""""#$$$!!"#!!!"!#"$"!$##!!"$##""#"!##$!"#!$!$"""$!!#!$$##"
@r1890
TTCACCGTTTGGTAAAGGTTCTAAGCNCAGGTGANAACANCCCTGCCTGAACATGAGAAAAAACAGGGTACTCA
+
!-H64)<$9@(1G40=1%!!$80H11!93<G$210D@):E1;7G4B,6/65@/:),@>)3/-)E,H"9"?88(>
@r1891
NNGACATNATNTATCAGAAAAAGACCNNATCTCAGCGCCTCTGNACAAGG
+
#!!%'&'")"#($($((%$%&*$&)'!"+$*''&)'"('"+&$&+&(+$*
@r1892
GAAGCCGCACGACTCCGCTGGCGTACATCGCNGGGCGTGCGCCAGAATCGCTGATTCTGTCTGNGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTNGCNGGTCATATTCAT
+
7#);<H%%H+*')6;;E"@@C'/3<7<37<)0<4(1/58$'&="1<%*%#/C7!9+83)(,">A226#8#@.'>F3GC,/C)"*-*!)=?(3%<'B+>C.&B74;;)%0,*#5?;.6,F6C)B?C79&E1E$21/0;0@"&!DH/864#.,07105='9)?=!/2;24%+1C+)5.$5&DGE3>6CHCD;#"36><=6.B'B
@r1893
GTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCG
+
C12D-*403F"@<>5-#--6@%1.C=>%G:95F%<33D$G:<,$FB62D
@r1894
TGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATTGAATA
+
9C3!B6BG=%&,,$.-GD69.$F$HFF2'%;<)6B9-4H"91!?6H"&3<02A/-GG4D093%F0?E4=+&***&*0;!E-E=C*/AE;#+A,1FF"1F58.8
@r1895
GCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAAATTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATNAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTNTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATGGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTNACCCGTCCTTGGGTCCCTGTAGCAGTAATATGCATTGTTTCTTA
+
7%7E152.7%3>&(F:1%<.@"759$%'28!$.D-B<B'A9/<3?A(0!*5!!<,.33=B7>C<)<D+1FH0*8.E67*7$.)'F">H/C/149HE%B:.5.;:6);='G#4@&B?GG)0:*GF4>/.#B<GE'+GD$$%,>(76E%H5EE.C:&F"$<<>6:=,/#(E(1>-A%.E$2,G-:"H.H1B;)F26D1=--%?#$*A;2B1=';;4D$+*>',C)G.3&BA0:$&<5H"="@?6F!@=20G>&,5B$2005+B3,74"1F!!#$HD.8,@<?FF9$)@"#(!"B'=$3'4+1=H6'D0:G;<H(@,/*B*3)?&
@r1896
CCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGT
+
*3#3&D"8!+<)+-='&E1),E>+>H-(&:/4=(3@'4-F663*$-"CH'2,+,23)=76:+0+6)2E-;,=?-')&B0"2AF1&4!<7H&7266=$@8*G>8!E3(,))*/BA#D>:91%3A6@-.+<%62C1,>7(">>HH.1C"A3&<E&F8:4)0)!?7A2,H5B;0$<;>)*;>!1A;5E%/;
@r1897
GACAGCCAGCAAACCAAAACTCGACNTGACAAACACAGACTGGATTTA
+
+30%<;!B+0@7+33#&F8+1#6&//6$7&:5;%->$H@&#9751$2#
@r1898
GCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTNCCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCA
+
;G)+="(!E1,%$4%1$6@2>F'!G9"$BB>%4=3H6>!1!%2*!HDH4'@=16C;@!"0H#1<+:#)G=H81*A-4,-+/;8&:>8E,(1)F&+:+DC?.B/:.G?*';BH$3,*CC95;6<G;
@r1899
NGACGGTGTTGCTGAATACAGCGTATNGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTCCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAG
+
(90!-&,D3.!*85CH%9B2$8+;%"@!960$BA0--F=,1FG=;->?3)9&.$5"?4*&22&E;"7)5:3-0>++A84>)$87'GC:/#E9.5;/$:<*A1EE6"+'#HD+'2D"G>,D"@8,??%:&EF.43=163=
@r1900
GCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTG
+
3G5-=@+&+E:57:?A6,5:@G:%#D,&?@+)#1#+'2-A!#B+HB,&;6.D9$>8H>@(=B"$35C<;?5%C,E1<@>(>79A0"*C"#6<G=#*B'1B7,>G-$3('353A*8
@r1901
CGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCNTT
+
9(?2D"DH,+!@F(DE8F/:)%6'::%&0@390$(B0:$@B'2=/8F9*B!?-"5,-*6(2#5D>;HE;CG8@8B>"-?##H*':4!""2'?(/9!)GD)H<7*'<3-+G.,3:3&@?=.56F3>))C:E&(<?C@B$#'+#2FC#:),,H'CA(@2>#
@r1902
TAGCTNTCANGNGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGNTGNGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGC
+
''#*#!#'""(#)++(#*"(("&#%*"(%!)'%"))((%*$+%*')"+%+$*$++#+#"*"!""$&#$("'$#$$''&*()%&!'$!%"$#$)&)!"*!$*!(%#(&$+%#!"++!(")%((%++$
@r1903
TCGNNANNCATCNNNGGNGAACNCCNCNTNANGNNNCTGGNGCGANANNGANNTNNNGGNCNTNATTGNTGAANAANANNANANNNGTNNGANGTTNCCCNCGNNACGANNNCNTNTGTANCNCCNNNNNTNNTATNNGGNNGCNGTCCNGNCCCCTGGCNCNGNGNCGTTATANANCTATNTNNTCGNCGAANCNNNCANCNTNTGATNNCNNGNNGNNTNGCCATTCNNNNNCNNCNNACNCNACTCNCNCNNNANNATNAGNNNNCNAACGANNGCAANTANTAAGTNGGNGTGACNGGCNGGNNNGCNANGACGNTNNNGNCCTNNATNNTGNN
+
##""$"#"$!$#"!!$$!###"$$$!##!$#!$$####"$!#$"$!!!$#$!""!"!$"#"!!!#"$!##$!$#$##""#!"!!!!#"#!#####""#$!"!##!$!#!!#"##$"#"!$#"!"$"""!""$"$$#!!#!"!!"$!""$#"##"!$#"##!!$!!#$!$"$#"$$###$!$$$!#"#"$$$###$""""!"$""!"$$!"$$"!$!$#!#"""$#"#"#"!"#!$!!"""$#!#$#$"$#!$#$$!""$!!$""#"!"$#"$$"$"##"!!!#$$$####"!##!$!!#"""!"##!!$#!#"!!##"#"!""$!"#"!$!#!!!!!"
@r1904
ACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCT
+
H6>.C;3@%HA+=3/(G)503*+1D@!1-*,F7"*<-0H2?:H4;=
@r1905
TCACAATATAGTTAAATGCAATGTTTTTGACGNTGTTTTCCGCGTTACCCGCAGCGTTNACGGTGATGNTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGG
+
ED<EC<(!$=<="D@F0.1':DH64>D16=*FF,A9C(,G(D*#*."!E@C#D3@'%>C223%-52?%!0"D<C,HG5B=9,39C86:42"2.88;DB:#45-5?$H3$').;=;-6&EE)<$;
@r1906
NGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTNGTTGTTAATCACCACATGGTTATTCTNCTCAAACGTCCCGGACGCCTGCGACCGG
+
!+'&'+)!(*"!!$)%#"'!%*&"%!%#+*+#%(*!#++(&*!#&'!'$($&%$)#!++'""%**$))!'$#!+%$&'!)+""(%%""%&&!)&$$+
@r1907
GACACTGTNATGTCAGGCCNCTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCTGTAATT
+
('$*##&$"$+!%$&*%&$'(#!##'%+')"#"+)&#%$+((&(*#**&($#**)#)%#)%(####(+"#"!'"'($'')&))$"+!(%'"
@r1908
CGGAAGTGGATTTATCNTCTCCANAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCG
+
:4$B(?/)A#%B=#=5!:0/'9-6!A0*?A+.?<@(9'!;>'EG1(9$12=+1:3,?>%1;1/A9"-H
@r1909
ACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTC
+
C'>C$8(85&F--E)2#4H&8E>H:.-4E9/335'H789&&'-3C!+!GF<C
@r1910
GCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAG
+
*HA9)=8#E*D'<.1F%3F&H;##6H3#$/5)"E?4&)<6=<4E0A32:8C.:.-=)=G$3.!+<D1D=+665$?";'#;@33'55#2=CCA<->:4;3)&-6B0&H8B)-3D-6+HA9B0@(D7?)4,665#1-"(B41>D
@r1911
AATTTGCGGAGCTATTAGGGCTTATACAGGCATTANGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTNTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGATTTCATGGATACAGGTTGTGAACATNCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCC
+
)..&>5=!D=+B0$9&$B!@)#AG+2'47+&&:E?/??'';?C#>%;86C::B7(F'G!+ADB"$>%8<00<;B(BA7$F",%F(#4*5A;E9*$&H!/@6-?#)$0:*5,4D#;B9C%<#C!,?:'@FE3B7@:)'$//)(,=,=H&<.+7.;1;'2+72G.6E4!8<B)8=1F?=A@=+*!7#+E51:A=H'G!%?'=5$?3BC6.@0715)G#1<'7$-*.!+"?$&)G(2>*?-#G4;(C#-6*2+("5.@%-?;D&)87H@,/A9;>C"CE"6D8/@75()!E/*:)/:)"9;$)'BD0")DED+2E);:!A&
@r1912
GTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAAATGGTTCGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCT
+
GG9F*/#D<B0<9GD:<+D:&@&>&H34<HH2$$209#-?,4=CHB&8D:B%3D*<80;D?:'*#9"FC#>0#3,37D6#:'?1;<@?2,5C?!<1?+/,0:>3!/)*&D!1!E6/;+GC%?*::?A=6?+="&7!&B:3D.6%?*(!CD)710*A:3(1+<@9$DD<A#H)@>&;8A%C1&@!+>!+C(*5B%6;H.9,!@
@r1913
TGTTAATTTGTTCAATCATTNGGTTAGGAAAGCGGATGTTNCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTATGTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGAGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTA
+
=;(<14"10B;*=D@)+,%)E5:&-(BA<C!7G)1?0B2+;*-406@*@C3)3#+7!(B&GH$@@3@6'<2::GF'+DG@'&6C;8&.@;8.7A"D55!'C@/9@C*6<"'$/&>"+!04CH9,$(!7FD:=/DF="HG5C!$=G%+"A3,*9/D@;:8)=6?%(,2%)7>"(+G$C1D2>@6:,1/342(/;,&78E5-1!75+EH/1C<FFC:('D:<*#;09A3,D.)FG%<3B"$<G"#;A$>.3%E'F8*,"E*$%34"/#C(7B+!<)23>;"(4-">73:@%2="=%#8CF$4<51((D3?
@r1914
CTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGA
+
H+2-B5%A-:EF0<93E<@"$9/+=#*CE7@/H!-C5G%B6)+C.G
@r1915
NTTCTTACTGGTTATGCAGGTCGTAGTGCGTGGCACACAAAGCT
+
!*HH,A-=!C.);B0G9*=!=.6,=*GA@/.G0216AG:>0&;>
@r1916
TTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGATTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGN
+
FC%-<9"?:-%=DCF-&08?+H@%).)$G4%8!8$;A?D6=:.&#4#BG"8H.-5/234:4.?<!GA@#$+%E(+-$2.=061H9!>(#6E$9E+50/$.6-G08H=12281F46B84+;$)D8#>H
@r1917
TGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTNCTCGCCAANTACAAAACCAATTTCAGCCAGTGNCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAGACTCGCC
+
;9?H5>&'7*<*;')9</5@25!G')1#=E15A5?!/,/1D:>>+AE)<"C>H$/D1733-5@4B=/@*@@.+B?()F#EH+/!C>,>/G4,,-F&F;+<.?2%30$&.+0.-->B3G5-&-$:-<H1<CE.8A%(5+FF3?A$F0G%B0
@r1918
GTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGG
+
!>#)"@3>;6->BHF@DE>=%70&4)"9CD(2<=D2@:D8C%&E='8&+D?74+:'-??;47)G#9B;BG"9F8
@r1919
TGTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGGCAGATCAAAAATATNCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTC
+
#(2(65?7A=(E!$9<>6-%2&/F?"75B*(=@=.>%2>0,E:&>8B;*F>H2+)-,1#(6@$4!1,#+;=9-3;A"!$;0B=-(6"@0BD3&*#&;>A)(<:&,?"9-3<+G6=A"<+.C)C!4>@B+@A"<>FE=('$,#FAB5BDDE*<0F!1;C!"
@r1920
TTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTNTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACA
+
5-;;$',2#$1.*2--0>(!9<H624947:64"(><84B84+9>C,:+0.7#;H(D',4#@+@63GHB6D9G8)+D1#?6$'='63."4G#55+D*<6#C$"E?E8%37.6-8-A9@33;0:GFHE=63?9*13*%1B*+822%.4A#2A7%10?@<2-=$?7%F$!=")/@6F)CA-':51G
@r1921
GCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACC
+
6AF+80<1,)8(+2B<34AH2?;+)@+7=+1,,<GB64;+;D2/C
@r1922
CCCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATAACCTGCGAACTGTTTCGGGATTGCATTTTGCAGANCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAA
+
./!!0G=:49CHE-E>3*#;B,8#H;2H%9?A*3'.BH1=D%!#/&);7;D7E.08':+>G:1E@';F/91:(+!<;)AG8&:,0)>7?+F(F"5$#)G((>D/3(5*58&H4/46F"2">C@C$D5*/8*%=#/$$-8
@r1923
GNGNNNNANNCGACCNNNNNNNTCCNCGTNCGNNCNATGCNTCNCGCNNGNCGCATGGCNCNATNNANGGNTNNNCNNNTNNT
+
"#$###""$"$!$#$""#$$!#$!#$$$!###"!#!#$$"#"!!$"$"!$!$$"!$$##"""#"!""!"!"#!!"$!#!"!"#
@r1924
AGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGC
+
4)#%6)DB34G--:-<<H77F8D.A;9&/&9@-??<F4%@1D/?84D:96',13H4=69'/-C*$%:??5*/
@r1925
CCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGNTATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCA
+
))+!&*((*&'$%&(#"")*'+"!#*#&+"+!"(%+&#&*#&('%*++!*&(*'!(!%&##"#*&&(*'%*)"%+")"!'+$$'''(%((+(!"+
@r1926
AGCACCACGCTGACCGTGGCCTTNCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTA
+
+%'(+*$$$#)"'&&+++(%''(%$'$)(*$'(!!*(()&&%+$#%*""$$('+)%*%&&)&+)#()%!((#*#$)#!#")&'))#"&!&!**'(*'""+$!)
@r1927
CGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGG
+
-$-"@-E30H(9$A092$382)<76BC42F'D-%2)!0=%7@"(2<C%29E5-87F
@r1928
ANTCGCNNGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGG
+
&#)&)$!#*'+(!"!)'&$*#*&!$))!$#*%)&+&'+!(+'"($"%+)+''$*"#*+))('+!%)(*+&+
@r1929
GATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGA
+
5C1D#$GCG7CFHE.+/64$,65,>&6B3@$!9A91,$,H+.D?'E-?>9'07&F607/6+F!?67B@0E'&?E5D$:04&3+D9&@6?H$A=:8(!D$+3G8315<+>8'?1$<0!
@r1930
AGCAGATTATAAATTTTTATGGTCCGTGGNTGTTCACTCATTCTGAA
+
8-0"=/)-3A-B79<8*!G,&34&(*!B"C*!*:">-1E=+A/$35/
@r1931
ACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTCATACATAACGAAAAACGCCT
+
)+**))*"$+)"("#*+#*)(''#%#&'!'$"$'*)%(&'*'!'&'*"""($)*%+&((&%#)*((!
@r1932
GCGGTGTGGTGAATATCATCGTATTCGATACGAAAGGCTGGGCGCT
+
5:H-&H%#:68C($&#!,*9%1-&2B5<HE.2343'G,+:++D!6H
@r1933
NCTGATATNNATNCNNGCNATCCTNCCGNGGNNNANTNTNTTNAGGNGNNTCGCNCANNAGANNTNTNNGNGANTNNNGNCANNNNTCCNNCNNGNTATNTNNNNNNNNGNCNTNNCNGNANCCNNGANNGATGTNNNTNNCAAANGATNNTGTTNTTNGGANGAATTNNNNGTCNAGGTGNNTNNNNCCGNNTNTNNNCNNCNGNANGNNTNNTNNNATGACTNNTNNCCNGNANT
+
$$"#!$$#!$#!""$"#$#!#"#$""#$""$!#!#""!$##!$!"#"$!#""$#"##"""#!"#!"$!"$"!!!$#$!"!!##!##$!$!$#!"$!#$""$$$##$$!"$#!!$"#$"$"#$#!!!$"#$$"!#$"##$##$"!$"$##!!$"!"!#!""!###"#$"$#"!""$!$###!$$!!!!#!$$#!#$$!"!!!#!""$$#$#!$!#######$!!$""$#!"!#$!$!$
@r1934
GTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACAT
+
057C$@F?HH+1>9*7;8=)!<FG5;2+=!G?*B0F$-<>D!@((!1092';63!!>)%B
@r1935
CCCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTANCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACG
+
,8A:04B8.>+<-,H>"#55D6<G5155;7,=6.:C3?FA#HE#/1).+3*>D.%/)HG.E8:'25F37+*4,+&;40G%C@2)=;D'%?,:E4:-$&:+-:-.F&@(3D
@r1936
TCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCNCCGCGAGTGCGAGGATTGTTATGNAATATTGCGTTTAATCATCTATATGTTATGTACA
+
#&#(&+''&!($*+($#)))'"%!+(&+)"&))!+"#)(&))"$')!)$+%("(#"!("(")%&+)!#'%$+$$+&')!+(()'&!($$$#(**&'#$&#+)*&*'!$%
@r1937
TTTTCNCNTAGCTGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGGCGCAGGCGTCCGGGACGTTTGA
+
))*')!&""&#$")+%%*)%!')$*)$(+)'*#&""'&+)$%)("%'%&$!(#$++*!)"%*&%"$!'!$$"*$))#(&")+!!!)'*+$#(#%!!)'++$!'##'+"!!)##(!"('+!#%$)$&*"'("*
@r1938
TGCGGGTGATCACTACCTTCGCCGTCACCGCCTTACCGATANTGCTGACCCAGCCACGGAACACATCGAGTT
+
+)!#"+!%!#+#$&%$&&*"+##**!+)$)**)&'!("!$'#"$(&+$$(&)(!%'&!*%'*'%#)(&!(&+
@r1939
GCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGC
+
9&HD-*1#''%$.6@B:+D#.@73F43;A5A5'DGA*5/562/2/<B&$
@r1940
ACNTCTNGCGTTCTTCCCTCCGAACNGGACGATATTGTAAATTCACTTAANTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTT
+
'(&*##!+*#"%&&+%$)+"%("$'%)!!()')'$++'#'&+$"&+)#"((""+*'%!&"&!*%&*%#&'"&+*'&")+*+$))%)*"$(!"&$#%&&%$'*'*%!"#&++&))*&+
@r1941
GCCGCGTTCGCCAGCCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTAT
+
3C(C%(:9/=!D&BA)4(E@59!HH+?"0,B(B=&4G0/4G";3<(&=B;>@!%!28*A*4)?.23&:,<D0CE.F;0&3'6#*>
@r1942
AAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTGTGGCTAAAGCCTTGCCCATAAAGCAG
+
87-%B$,8,#1&GC3%0<$9A;A*)7"$9:#,4+=3"!'.D=D09<$DB1#88?D%147>(&G9A%28F,H=:A"A?.+*$9&5,!,5'(+&4D
@r1943
TCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGCCTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCNGACGTTACTGACGTGGTGCCAGCNACGGAGG
+
+(>9&(D/5-H+4B;2+0+"D8,(4A:EH+2)!*@D!5'=#BD/9D/45:#;4.@+FE+9E+#--#3?@+%9H<2=)>/?8/H1";A2"3.A,$A/06H+#"5
@r1944
TCATNTAATAGTATTGGTTGCGTAACAAAGTGCGGNCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCANACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATC
+
'%$!,(:61F:F?1808A=A5B1A#!A#-64>B-8-HD/2<F$028*<%)G.&@8)6-2.*-@*)G)+(2*G?$#E2#+7=BEE45+'0C@B7#/+".$F0:;5D-%B*@9;F#1+0<1<E2$&:$.%8G28%GCB*4!$!0>C(>+:?A,5184&F&1">CA00<F-,-4:4.+5-1'";,<05#046E=9(7
@r1945
CNNGTNNGTNCCNNNTNNNNNNNTGNNNCCNNGNNNTCNNANNTNGNNNNTGNACTNNNAANTCTNTANATNTCTNTTGNTATNNNNANNNNNGANNGNNGGCNNGANANCNNTTNNTTNCNGTTAGNTCCGTCNANAANGNNTTCNAGANNAAGTNTNGGANNNNTACCNNNAGCTNTTANNNAGANGANNACCGCNANNAGNGNNNNNNNNTAAGCANANCANAN
+
$!#"!$$!""!$!#"$!"#!!$""!!!"$$"##$"#"!!$$!!"$!#!"$"#"###!!#$!$$!#"$!$##$$#$"###"$#"$##""!!!$"!!#"#"!"$$##!"!$!#!""!!##!!$"$"##"##"$!#$"$"#$!#!$"$#$"##"!!$!""#$$""!#$#$$$#"#"$"$"!"""!#$$###"""!!"!"!"!$!"##$"!#"!$!$#!$##$"$"$!#$!
@r1946
TACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCNATTAC
+
*=9<?51C*!A81A.-!31H!'238;G.*B37G%5$D.'9&%3A1-7#"67+@1)#DG?@AGE);C*B0*";4&%&./7!3/*H/;"$62-
@r1947
GCGANGNAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATC
+
)('%$%&+%&)$)!('$%)#+)*'#*!('!!&%&'*%$)#'$&#)%)$%%!
@r1948
CTGTTTTAATCAGCCACAGCCCNGCGCGGTGTGCCTGCCCCCGGCTGGTNCAGCCAAAGGCATCCATCTTCGTAACATTACGACCG
+
*.C;;"'("E'0,134C>9!34=.-'77CCFA%D=78(>/40&5!<.C?:1(+%1&+B?'D$H0B=@E'D8F5)A+)>?F*(!$@D
@r1949
CTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGG
+
4/47$=#--:16AD)7*DA,,.='2686+3:2CD%6&(:/F(%
@r1950
TTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGC
+
:5*-;0?C#B*>&GA=-*-/BC;966#C-H0+70.$1G,F@6C(3$&H5(5G%F7+=??%EB48!A7"0653&/CA?3$()%GE8*EG=00/!/A?
@r1951
CAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAAAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTT
+
,H<@E.@5=:*C/0-D96:4!&889="%'B9>:.HE9!+013B'9H=>'<G9BC6D4+).-'D3#.9!(,19G/#,58$#;2>-,82@:9?><!BE0*-AA9>'3A0-#=79/E;H.=2)28"F/9
@r1952
CCGAGAACTTTATGAAAACCCACGTTGAGTCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGC
+
?4%!C$@?'$.*4F5=>*F3#+5=$4D7&46%#F;)?0&D?+<%F)2)9*#;B@@?".B1F=!1D+B,%$@":<&+)H=G.&5*=;D:7G*H091A/9F),1-.6F.0<,C5,/@GE;%*,7AC1,2!,H58)A&=+2/&DFB
@r1953
CTTTTGNTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCG
+
F?7),10,)?%*9,##C1'4;#D5:@:86604%H>8$5FB3(!,4)
@r1954
CCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCA
+
''>%2!:A8@9$9$9HF,?0D<-=E::;&"."H>+<&#,8A'B>*>4*?>*BG<41)'*F'4)G88$9?+F43D1<.??=35E.>440-??3B==9B9:&D<>6%D?%;6==!;(D&():G7B&D((AFB!>")7-=::%)>#A/H#7$F-HD=3+9E"71'$.)8/6!8B$%C:;;C"<@E>%@4>A9A?E<%D1G?=6*@/66C'*@6#B=A1#=10:<%<-8.1!
@r1955
AATGCTGCGGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGNCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGT
+
D-;.(4@GF4*;;?1<E0;/$>H5"0;*4(#)%;+H'D14,49E=3*6>5":-A(74!6.2<6$B50,F$+F:#%-A190G$AFE2A7%7=*?G==B:24BA(?H(0<G0$EH(284E4DDA#D<#5405434;H'%%H&#'*0;/F-8=
@r1956
NNAGGTTATCCGTTCCCGTGGCGGCTCCACCACTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGATCCTGCGTCGCCTGCCGGATGAAGANCCGCAGAATCTGGCGGACCCGGCTTACCG
+
#$6;-:?92A518*E*G/;2A11(96#F#73='7>2%-F66D+@'.GC&G;*+2'+64H:.)-?*<H#110E+<(!A*@:#"78@0D#:/F45F)E64$2F=H=(<@+?13+4;=?$06!!EBA.C!!?GB05>&2H(B98
@r1957
CGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATNTATTAAAGGTCTTAGGGGCANCAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATA
+
'H?)'&,396,&9$35#'8&,,/&*&E"&34G$A',-:6F&3')&<?;"62H@:!,4A&<**"HA5/,&$;.$-)*#<C0:7?97+G=5!+6=08)8+)8E*,=CF0G=&D8%507<F!-$,5
@r1958
NNCNTCCCANCNNNCTGCGNANANGATNAANANGNGNNANCNACNTNNNNNNNNTNCGNNANNACNNTTANGNCGTNNCNTCNNATGNANAGNTNA
+
$$"""!$###$!"#$!"#$$""!""$#!#""$"#"#!"$##!"#"###!""""!#""#!$"$"$"!#"!"#!!"#!!#"#"""!"###"$!#"#!#
@r1959
CTNATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAAGACGCCGGGCCCGCAGA
+
=0095D.@5$903F=4=)3C<+?:3#0?*:2..;91<*F55$9%H,)7,GB&8/@>#-9>-9(2:1'>0.32'=E8E<640,3=<;&96E4=5-
@r1960
CATGCCGGAACAGTACGACGAAAAGCCGCAGGTACANCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAA
+
=((+#/-=+";$8%995H;3ADG!259)'2)C3"#:44;9&@;48.B30,C6?0B0C/@*A2F9*>=662%G.4B-'H#1?1>
@r1961
CAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATAC
+
CE73G)8&%2,@1D=%/)F4&,*$/@H6DA185DH4A=@6+40(E?'
@r1962
AAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCT
+
&H2E'F1:DD+DG%<9*(452*8E>D//F/-625FH$$0/0(+-7
@r1963
GATAATAATAATATTAAAAATATCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACAT
+
,$G9(1(E/=*!=-#=&.%'$A=5H!@4!!AG*;0>>4.6;CG$A'H@G)D*0$=,?,?-"$*/+;9E;D;+4+"@%5.;?57.'5%>6&'%C
@r1964
TGGCNCCGAGTAGATGCAATTATGGTTTCTCCGCCAAGNATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCNAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACG
+
(!)&#+&()$%*&('")+!%(#*$)%#""#"$*+#!("($&#))%+&#'%*&!)(#)&&)#)%%&&'&'#%*('*!(#%!("(&('+'""*)*+(%!%$%$)!$!"%!&'%%&!$!*))*&('
@r1965
TCGGGGCGNAATATNNNGGAATNGANCCGCAATNNNNCNTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATG
+
'))%'*'("*%%"&"$!*'!'('&)$%%))"))(('!*$+!#'('$$"++""&##&"&+#!%!%++""$*"&)(%%)"!+)*#!)(#+!""(&((%&++%&'&*&%('!(%&)!
@r1966
TCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTT
+
2:#/0(H-2?GH::;DAEG4.)@"'"CG"3<0043C268<:/7+?8&6CE@)'C9
@r1967
TATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGAC
+
-=?=>$B7>:%*@6>=&<25,&$+2=7)-+%,'""%=""5/?2(C#3-E%)G%4<@3-G-$%2C';2#G"02*4F,+*,25-AG$%3%E4&*$>F=F)=?;-;;AC*F!=036;3AEBHE+=6A0:!%9("590)B>F.3%F666E4):3H"@#+F:7"%&";)!)204G
@r1968
CGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGT
+
8C,8!)D,=:5;)#(=,B$B(+%4BHF5G,D!%$91:;EB='-')<.G9)
@r1969
NCGGCCTGTGTCAGTTCTGACGNTGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCNTTATCCCATG
+
!0,F'"B-305;6#."-8,6?G!8EA(-9H3A4=(1!1D165&?6B=$)D6A#B,C"0%2D&4*&+D?-HCH,G;/"14=D3
@r1970
NCGTCAGCCTGCGNAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGGATCCAGTGCATCACGCATGACGGTGATCGCACCGGTG
+
!1<+,C'#$B=$0)6D2F):'=75F#?7&(3EAG;)#27+;@8H%.)HD@FFG7&C35D3+2!*#?(7(G00@>BD7>(H1<)#:+$-DH)'!+D:&&4-4A&:@/,@))4(A2>#C5.GG/&
@r1971
CACACCATGACCGGTGAAGCCTTCGATCCGGTNGAGGTGGATGTGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGACACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCT
+
#,?!-<$.$4)/89.+#4.3$5D#-<$=0#.D%2(91&'%",-$-%<!$"&8A(>.%@1<$H:40370E+,;8*A>D7+$&("F!?B5D:?+@'?+/'6&D%+8"G4;7'D)+.A"$-C872</=*6$)>/@"F$D6G.F>G/57-%*189&".26ABA1E?8"(9+4!6=3:@"G91(*@4(?D';.G->)<8)@
@r1972
CCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCA
+
E46:.G=0G)=,&5<E59DH7,2>2,'D2?:0.&"CF(D745./GEA).;
@r1973
NTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAA
+
*3<@,B&G4,00(A#6"'F:&,*+4')?.1')"3B0/9'%'/916>!3+"$!F0)H+2;
@r1974
AATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGANTTTAAACT
+
1HH<)%?2E095C(2/?1@D-9@9<.4A"7-H97G*AE/&5&807D?*7?4
@r1975
GTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCGCAACGTAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGT
+
:2B@#6.3+.44G9/B)0.22$D0F6@?D7!!<#F2,7)=306,1)B"27BC0390(0>+10+>9.;=-E/8+6"<@C?,-C*>=<F@HCA51
@r1976
TTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAAT
+
G9"0-B>;,5?-*,4:3H=4B(AE8;+!'E)B2@,-"1>79@&
@r1977
AAGCATTTGCTATCTCCTTTTCCGCNACTACATTCCTGGTGTT
+
</3F(:??610H!%2!98!:8&/DD<.0*-8-:4"'7:/'E@%
@r1978
AAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATG
+
=+!-=*()A<#A>"%AE4:!?A44(2GBD9@"/'>AH%66F;7>/'+1>A'/<=C2)3'D03?B:@-
@r1979
GAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATAC
+
9#=@(),'?#,5B5@5F6H4C#'/!)&-00G#:#"<HB@6
@r1980
TAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGTTG
+
,:8?(1<?B,5E($&7?BD+G:%A5-#7BF5G?BG?0*#*>)++G)>$0?>A(C?$8?722*:5)AC*$!F0;@!694*!;257H4;#82E6%827-.9"8%+,$!":@=%G89:E=(3D!%*G$)A'8.")8;0/,3;#-.="?;G5#
@r1981
GTTGGGTCTGGAAGGATTTGCTGTACNGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTT
+
2<;:82<23;<!F@D<'@>"+E<<?1H1A)6+/85@:$>3?CD<&*":::.-?DB216$6*=F,"<(F0":',*3G'-H93
@r1982
AAGNAGTANACTTNNNCTTNCGANAAACNTGNGANNNTTCTATCTTTCATCATATTCTAG
+
*%*!(%($!(!#"#"$(%#$'((!&*#(!(#!)"(!%&)('*(+""&!'*$*)$(%*$+&
@r1983
GAGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGC
+
+#3E9;.%,:=09-@@8014$<!:B(";G7)2=F8!,4%:1E">0-C,
@r1984
AGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGC
+
);)->8$)(9,45+3-B!(+2.)/C#61HE@6,+8$?2/+8.(@E?AGH/??6"B/?'>1D7:5$+F2+AHD?5;:#/H)=-.ECF.!2!>9'8C0"(4#!
@r1985
CGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCT
+
>G-4/$.5%*,+$2(=3>-=4B&#7G=#(6A-&",@,/:!)5C/5(DG$90F45*BA.
@r1986
TTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGT
+
*07B4@+@<8-D,'!/>."#&>;?$30E00+:#(C7G,C$9)9!/=FBFC)1(,$"*5
@r1987
ACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTG
+
A3#=B&*?FB!B'G<4;=117BB*E"4214*@008/C/8*01>*7'1,&(6@8CE5
@r1988
AAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTC
+
=?>96>?><@>-:(1/3+G";E4"<7(?G!,F@%A64$C:$F+D##".:0%)H>=80B>H+
@r1989
GANGNATNTGTCAGATTGANCGTGCAGNCAGTGAATCCCCGCATTTTATGCGTTTTCATCTTGCCTGCCCGCATTGCGG
+
#(!&#(%#+!%"'**+'#$("#&"'&&+++)&'()%#$#++++'&+!"*!#+&'!((("&*%'((*!!!!%!"&#$)"'
@r1990
GNATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTNTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCT
+
%'+"*&+#*"(&&'"#)"*!&##&+(#*##*#&%')*'%('))#)%"*&+'&!+*$#%#%#+'"$&*"*%$&)(&!'%((+"'')(+%((%!!!'$+(**(%!&'*!)+%'"$#)*!)!&"+(('%+&'"+(%(+%**(!&+*&'%"
@r1991
CTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATNTAGTTCAACCGCAACGTTTCAGCAGCTACAG
+
4=58<./4F)/0>&80CD#'4BB*<H*'20!#51*-.)-?*:?(B+29BG+!).,A9H!C"<+:?<:2;9-16*!>":9#&=8DF'1,.*-C/;)#-$<"9$-=5>.>'B3*+'/8H).8-)';5(:!-%?8D&@F+,G&/!&%@C!AB<(?'%C<):,D*E$?H4F,B26)
@r1992
GTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATNAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTT
+
?#HF/&0("49!"E4$"F65=26((0GH).3;:,(6,(:F'46@(+4(+#872'38:/4H5;E*C7&B"B$1@6F&;F.4)%;5#F?/,.>-2+E
@r1993
TCGTTCTCCTGGTCGCGGCGTTTGATGTATAGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAAGTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCNCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAA
+
F#&7@30&"EE!GH/';=H-#F7G?&:$8BH>E(3A"<5*>D:@&?1A24"89;8+>7=$5/#;380E;);>?3%7,1"'(*;#<FF1CF'<D6$,FB'?@(6E%C'37#>-H':B7HG47=9?5-H483E#.C>>!>G1!6@C*#0#:"(1!5+C+D)F;H!*($A$(,8+A67&E;2C4;@"=G"4#>+(3E6;C1;A$%43;(/")"6F=C(*DFDF"//F$738%;!E/='.6<*5$66D#$
@r1994
GTCAGNCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGC
+
'H).3/3&6AD#;AE0A"';6;($<*GF<.F6=A0C"//>(E&4(7:A<GHB*A"/)8E?D<2"%5(?G#9E.,"D39:G)5@+@0#=,4:<.&E363
@r1995
ACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTTCTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATC
+
<D5A%$D/9,;?9DB0&DEA%A=')4@A-7!>/,#0+,&!6?A/<EG9$<:4=&8B1@H"553$"""7.9E(C=18>.0C9#/-3<>(/6<0'7,D=-&*A/$+G=E+F6#""%,G?!241995"($?*D6.2#4,1FA";B+CH+F";:C5#2110;A55,:*>8$(=5-.*!+B15;&,'<,0,8,"(.E7<:"B4,=<5?9&<#5<95B!-!>?,>!CF-F>":&%?826
@r1996
CCTCCCGGCACAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGGCGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCT
+
+$#+*''(($$"$+*"((%&#"$!&%+&#$!%!&()))*"&#"'"*%"&*#%%(!)"((+""&"!+)"%%#(((#")!#!&)$")+)!''%'""$#)'()(*$(
@r1997
GTAGAATNACTGGCTTTTTTGGTGGTGCTTACCCATCTCT
+
*"*&+(%+)*'&)!&'$+%%"$%%%'##"+#"&(+##*(+
@r1998
TTGGTCGGAAGCGGTTATCTNCTTTGCATTCACCGCACCGATAACATCGCGTCATGTAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCG
+
25H8/&BH&6#B-A>>>G&>)+(1.%0(-*1F'G!9D?6AA3C*9$.56(,>$!0.$A,6:1BA5B&)B!5>(;2?9D7?G'-:51?E4A,;1!D7!"7<>#480,?+H'F:0DF4G(2((80;+*C?D>
@r1999
TACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACNC
+
<GA7<E+>DB?7=&H78ED;@5!&!%+)EE<.(2#=<@"D/./B+?;@A.>%E:?4'&/"0);:10B:C@*%
@r2000
GTTTCAGGAAATCAACATNTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGAC
+
F>E93!>:)@G2=8@;13:""GG=D@E#+D;<F//A1+G2,A#A;G>G71&:%-&-
@r2001
GGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCG
+
$G$@@0@(3@!/F$&A!+9>88:2*3?475&:#'(3==A%9B*0(+#CA6:CH(F@&69>G;02-<;,B$H)G<8
@r2002
NCGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCTGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATC
+
%F"76@54AA58-44-8!$5,.B6,:/+)?F,?*G<4(!*,$5#A5B(29@@C<1C%;%),-3)%.=./20D7<4<%9B2BE*:FGF;/!<641!0H.8;%#>B"'2<5<,4((&-D4=;F9!8)6$2>3BAD$-5<&.AFD,"9A($B51B.-E/EA:<F,,/A?#=--D$C<())?03<1?4/9E"$/<#F>$4G=,03@D'%=D
@r2003
AANATGACAACCACGNAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGANTTGTTCAATGACACCTCAGNAGGAAAACGCCCTTCGCAGCATTGCCCGT
+
&"&*+"*'"$($+#"*#)'$&%#)**$'%"'$+!"#(*$#(("%(!%#+($*##%*!%)"%#&')(&&*%'#*!&+!(#(&(&#&'*#$*)!'$%*&)))$*$!')+%*!+('()("&#(')!()
@r2004
AGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTTGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCC
+
541C9*<98-,<4&6B8A9,2*7.'H7357'*(A*/@*E3<#1D8>:H,#!'4@FG7?F72F?1*G%6D/:D.3DG3-#B"C<:4A(6?#6&94G33D@&H>(4%$(;$62.:/$C"?D5%C:+5+<*9?0H4+@955#2+2C*!/1B&9E<D,$'E9'.6E'F)%)E5>4A>HC(/0.EC
@r2005
GGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCANGAGATCAGCNCGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCA
+
$'0E>+%?D=F@=7):(1(&3?>(<0//7/1>.G"%-A@,")4-6@(94F1!/E5%1!&C$A"E&3=6*#"!8G8"9G-)(@/1+E.4,E13).H"
@r2006
CATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGTAACAGGGTGTGGAAATCACG
+
#E)7&E&$%>894"B<)D$.1/?;*>'376A72BD('%H9.F6-,#%(4@:G*0;9')
@r2007
TCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATG
+
<A#%5:/+4)B<!<!G',9!*1H)E(3/7&?37;.(-(E>
@r2008
NCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCG
+
$E3!:B&:)D0+8A@#;=(15+**,>.3,;-G8F;4'""@@7<B367.1(92)H)1289>!#'(C+*.5->0>G4B2&#10F1?0<F*@C=5@*&A5D11!%/&&4:/G):$5C/D-3GF'7=B/0,.
@r2009
AGTACTTGAAACGCTTCTTCATAAGCCTGAAGAGCTAATCGNTCGTCGATACTATATATGCATTAATAGACTATATCGTT
+
++&)***"&$&&(""!&$!*"((!))!(*)!*)#'**&'+*%$+#"!%"+*"$++!')"$$(!'!!'%#(#(!*)%$!(&
@r2010
TCGCCCNGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCANATTATCCAGAAAGAGATTCTGGCCGTTACGCCACCAGTCATCC
+
#E,;1@',F)9BFB5';DCH$76>9970@,%5)&%+4?0BF-;0GC#H8CB3DD8"15*>=/0->:#?A5/1#&7F>?58'++D!E>;2G1/D2)@
@r2011
CTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTC
+
/:39GGD9'7)/4-.*E$&2C<4'FA-G%595@DDGB@3$1=%.%'D=8?
@r2012
TNNATAGTGAATGATAATAATAATATNAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATC
+
$!#%(**+'"'++$+#!'$$!##!(%)("***#*+$&$%(")&((*+*'#%")#$!$#&*"'###*%))%''%+(
@r2013
NCTGNCATGANNANTTCNTGCACCGCAGTTCCTNTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCNCCATCCCGC
+
#'*'!"%'*$"""!!!&!+#!&&("$+&))+%(#'#+&&&$"#'((+!)$(+)*"!(!+#%!*''+$+*''+((()+)+'&''!)&%'*#$+&"+&($)'"##!(#&)(&!(!!*(&(#
@r2014
TTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTGAGATTTGCATCAATAAATTCTGACTGTAGCTGTTGAAACGTTGCGGTTGAACTATATTTCCTTATAA
+
?7B$*7%,)&A)$@8E#CA"!5(440(=!;&.2E:3+$0?.!5A-C=E$H@*)4>'7E)/)5#/&&.-<3!2,=B1.(&$'B73#-/;<)=2G+&H=97"*9!C>B"++7A%!H9G3"F-:D-$A4$+72&3*%;284!2$-;
@r2015
NCNTGCGNCNCTNTGTCATGCCNGCCTGCACTTCCTGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACT
+
$%"))$)$""#(!$++((#%%)'&)!&)**"'"++"*)&!%%!"($#$&$##)%$%#*)%(+$"&($+(#+&$'!*%()$#!!+#!#$()+"&#&)"+(&$+"!+*$!"&
@r2016
ATTTCCNTCTTACGGNAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTT
+
+&$+!*&''!"'*&!#%')'(%"(''#(#+(%$**(')(!$&!&(')(+)"'('+'*(!%""!)'''#")#%!&))*+$(+%&#")(&!*&
@r2017
ACGGTCCGGATCGCCGGTGGTCACCCAGNTGTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCG
+
**'!!%&+)'+(&'$"''$"")'%(%"'%"')'("%%%*+%#+'$)%"(&!*)%#)++#+!(!*
@r2018
ACCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCATCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCCGATGNAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACG
+
$69!&4"H:>'7>A455!>7?B*-+*%825,,H6=?AE:(6;,/(3$-.(H/GE"!"46:+,7,03B0H.(6G?!=%EH+<+F62?G-'4)<4)-/F4B/@16#>A(1G54)',6F*B14G'>.0AC!"6E;@@"-!EB55*1(*=3<!7FF#807H$(H&('8%'9<)C$<@?B,-0*9:*C?")H5-G7:*-6<1&'
@r2019
CACTAATGTATGAGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCCTAGATTGCTCTTCTGCAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTAGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCA
+
?=<2"D&$&./G0?0>!C.7@!639G/.7,EH6?:H58D&"?16HD(E3>;&'1+$4,G)G@B?+:8,"0D$G$(/&34"..,F0@9E.?E/:-%9)-F%4%D3C@4):)).>-E1?.0@.BE2=:H:HG1B7;B2G<2"C=%+3*G+7*C:39GE;#)$-2$'C88'(97:G77:@:D2,6.@47(%?B#"1>GD=BEE=6"HHH,'&'&:HC">BAC8+D)*>)")C)HE1(%8!H
@r2020
CAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTA
+
'<84)6#>=/"++)+'C@D2@9C(%GF<&..G<<H<B+9/?*4)(A$(A!17(*$D,(6$'>&+H9?+&A<4D0
@r2021
TTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGNCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCNTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTC
+
@50C69<#15GEE4+>>@"33715"1!02'@,3+.8HD1$+"230A2#E()%#F0%30E*CB26=$7/864',CD/&8/#!G:9D7(A0$C;5#1#&G#=$F4;??3A4-A0"GD(8&+F>'35:9.A@<H"(0D+:/->HD'?F67FD,H1DBF#""D"2BH?3-'9:)=83B&-!8*!%':)
@r2022
TGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTAATTACGGAAAAAATAACGTTCTC
+
+BG;+-868'A0+#7&B$A/#-";<6=G:?A,"%E<97>*F1F3=#$747*>(E=5>5/1C?0895D
@r2023
NTGGNCGATTCAGAGCTGGATGCGTGCATGGAGTCCCGGAT
+
#)()%#$+*((!$!"#+$+%+)+')&$*!'+#'((*"#!(*
@r2024
NCANCACNGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTG
+
%($"&"'&+!("&++()#+'*$))(+#!())('")*#''('"+#$"+)"!'(&&
@r2025
CGTCACGCACATGGGATCCCGTGATGACCTCATTAANAACACGCTGCAATCCCTCCTCATCT
+
F=GC=B*G4E'5E$7E#5&E6#&(952!*FG/#<#B,+"E&@8*G1(B*2F(B$@<(!F90C
@r2026
GGTACAGAACTGCACCATTNAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTNGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTT
+
??,%?&.ED/%)68/,.#D3(8#)&>C*@/*-85%*-DA)8F4F&)31%2(??-(#*+2-GB)'(##B:3#?G6-0--G5::*?G,5'8H18:=0%2/(%&>%-;/'/73%G@/F?H9<$(-2D#2<362+?A5>A#*'3#EG9D-'.2)58
@r2027
GGATGAACCATTTGCATACATTCAATCAATTGTTATCTNAGGAAATANTTACATATGGTTCGTGCAAAC
+
:!3@2;H,A*'*<)H-H-(#&@%%<2!>)5?-67#;<01"F+GC47-$<%AE/*<7<GG0:;F%9E<$H
@r2028
NATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATA
+
%F/?</'8:B7:C$G,>B4*/!7C08D>E/!-=#-CE&'5
@r2029
CGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCG
+
;B7414$.5G,@.>GE#1D%).B",94!47=@*@2')B-,E*%199-,1
@r2030
TCNACACGCAGCATATTGACCCGCGACGACCATTTTGCGNAGGTCACCTGTATCTGCCGCCACTCNTAAGGCGGCGTCCACAGAAAGGATT
+
)#++''$*#'"+#*(*$)!+!*&%%#%!"$&"*()#&#"'*"$#%"!)")(!"*)&*"!!"')"$$!+%*%!#'%!"+%')#+*+$*'#*(
@r2031
TTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAA
+
/H7F3$7&C4$%+,+,&5/?7)!E?G:CF,#E*,:H.,7="$'?H/C5=;(&*,#.+1.*-!:*0/@"DE/H0H'6;HE0)4-51060@B(1,.767HG>*4-:B7'E-
@r2032
CATCATCCGGCGAAACCCGATCTACCCAGTAATTTTCCTCACCGATGGTNAGCGTGTCTCCACGCCGCAGCTGCCGCACC
+
8*?$B)9(;:,497$3@0#&>*-'G?,F(:?F3/HE?HA!01'H?:,.2G0)#-9,:(?+-=B$)45?48F:>D:@9D/E
@r2033
AAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGNACATGGTACAGCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGATAATCGATTCGTCTTATCTAGTTGCTTAGATATTGGCCTTGGCTTTATCTCAATNTT
+
E'D>F7"55H9#,%8A+B1F''(,8$1*$:#("7*A0@7,@A:@H'!6.1$"680%$;7FF0"$*';'5.A28>E%D*;E624@C88)8%&"F6"F*-'2?@?*-?&56>=-&-))DB2.=F"F:',B*'1)3%!F&1(>,G/,@?(+&H"(?6/75H6
@r2034
TGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCG
+
EF3<7=%+G-;<=:%E>F4)'%5&D1B2>,+:3<7#6G*56E8C%C/B
@r2035
TACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCGGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACGGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCC
+
()48940'=++.)@A>03B-!AE733#;'CAC-?F%A7*'68,.311#1#!06342%G.+;",;=6.<!G$2$*3+AH,B5H'*?09962!,8=2E+20'E=B(")8B1%4#6($$@=B*G$%=*6,%:E;G4!8)'')=&.F(;G36?'#7:#50A:;2?F*=2,"G%018(>,&6>14):,G6)7%3&$!C)1DHD:"(>(75*64=G1(:.B$36G0$"=H28!#A5
@r2036
ACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGC
+
=H6=?A7E"<:-;8A$+>2&-0:<#9%%>,;<7DDFC4%?-C
@r2037
TNNAAAATTANCTNCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGNTTCTTATCAGAAACAATATAGAAAATTAGTTACACAGGAAATTTTTAATATTATTATNATCATTCATTATGTATTAAAATTAGAGNTGTGGCTTGGCTCTGCTAACACGTTG
+
!""%*+&*+%("'+%($"$!*)$$"+##"(*$$!$##)!%%%&)))!%'%$$'+"#%++%+%!++)$&%%*%*&'*#*(+#%)!)#!")#'+#'*#&(%$%%#&*#$"(#%%()!%+#!#(!%!$)"#"*'('!"'$($%)+%'"*'*#%('')$%#")(+!*"!)")"
@r2038
GAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACNGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACNTGGACCTATCGCGNTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGNTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTT
+
<"G"E2)847>$&FH24H2C7(1C",6%$+81>&G"2A;G3><0.?A83%A:A2+=6"<+$#"F%H%%,(%:%/E*7+)?E6B/)A9BA0:E*2&G'H.(&0H=!H1D#:3&/"C:+'3;3:BD#6.B36,E0,E+-D")*&E1A:+D>*D>"AE!"@10F#A!*6/0G)6'7>05!B43<8,?3$F%/A+>#3#?3@H".0'*0!18;:)F!9D8918":D6!2#96"C&4#/4(37884/98):,)A4>-:$!7'G$(%5@E('F?0>A&&D4#HE%!5G&C,F>FBFE3-&B28-59CD=F%FA8F@EBB**5<#D7*:=4&'F*;6,,D=?3<AHH$<$&.-.,&G/D71:&6*0-13C+;1C./H2*8-G2:$A<5H)954+0F
@r2039
TCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGAAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTANTTTTATTAAAATAACCGCAATTTACTTGGCGGGAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCNAAAAATTAGTAGTATTGAACTTAACNGGGCATCGTANTGTAGTTTTCC
+
5A:90*?..)6,B3#!H,356/,7).@7=6*<08?12)E/9A-ED'$%:=+AC;/DC5;A#9=..#@<8.2+-%/6E?*=/B:9E+C:E'%8"2'6"94+.*E4;>51$!%9*);8D*2+8/$19-@&3F22"/?;;;;76!,B3?=:'&4#F<%*2E=B@%F6'@,7='!&=&)G#G2:<>!&/#D#0>$=H)1GF.FB4F&10-C878*FD+D1,+:/%$H<FBA+;H,6)=;
@r2040
TTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGAT
+
/$H-<=78<#43<%2+F$=;;(A+16::D?F"G.6%*@=0-H5:B9'8"%A=
@r2041
CTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTNGCACAAAC
+
3)52',F"H8+GF@)0;05&@$3E74*7:@'6#+>E:)!<,D5H+3EF(?+D!*;<%+>2F)>8!E-
@r2042
TCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCT
+
'793EF:H54B.<%6,$:&E@B//,&2>:)A*.,&/85<%#6,'.!?89-?D:/2@8>5!><*;"$E:0;'&'=?D,-HA8#3-A.*@$*)(A77/B0)?4/@:&C%?4;":D3A'CH+%F;=1
@r2043
NTGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATC
+
19'(H*1;C?#*!(53>00*D(8B3%2&+-4"#A=4HE0;(5;%)&%%>%+++((A45+6#B8#C#<52;E7,8F3)/BF+((#0*%BF>4-/9A4C;7%=7,7CD.9>,9)H"-
@r2044
CGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTG
+
!&>##+E4?>'1H#EE/@934G*8C(/<'"4"2H$(#%F*?C&$GC)330%=D,7&4F>'!(A0+2D".5F#=B7$/@!9E70*6H13F!!<%##2(4G?8E;:B!*/?'7HF))??.:E,4A0:0E$*
@r2045
AAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTG
+
*B:3F%D+*67"%(0,0>(10H28@(74(7*0D..A@*"2;;GE?9=.
@r2046
AGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTC
+
'43.1>F8"@-<-C;84HE%$%"8+A$2<@('(50(:1>.313!++"%2)2#00.#.<GH"24@G8;""H;8:/=+(9(5*7($&#6++H41/#64EC4H-.&$!(H/#AH.<5%GD==(A
@r2047
CAACGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCNCCCATATCATCCAGTGGTCGTAGCAGTCGTNNATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACC
+
E58"=)716&8<&<3"4!>2?06+2=H=*$+=:.,:"0F,'71%69*6$*&864=!CG<E=(71(9G!D#$1FFF2?.F:5,H<&/%50+2%F//%.G)E$291&%;+E1)=23-.0A9H=8?"#??D:F5-H:4"/:!5.$=B<:8A%45?8,7!?,*#'1:"E+8B71%.:@;@+>'%+;.7G$*0A6D,?*B.&+:1G3GBEB&GD-<'0H48";/D0,:"3)!=D
@r2048
GGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTNAAACAGATTGAGCAGGAAGTGCTTACCACCTG
+
$99$&6BD;6.!2A;,B76A<#29.<-?(.;AG)5H?">+#A.9#&F4;6!0$;7.<9=',-4@4+,G'AC@!*;4'%)B(+)=$(!/<.EG@$"=!@'B4()B!;7'CE
@r2049
GCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGA
+
$+()*("(($('#*#("*&*$*!"$*%$("!$(!#)+$*%%+&(%))((+'!(')"*"!(*((%&#)&#'($#&
@r2050
TCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGAT
+
C/9"FHD2)/B:D>';,G*,%1-5("F#+$:>5%2A;?)C*?)1)7.>D,8E0,=G"A@..(9)%++"<=7193+FE-!5<53&<>25+=+8A1$/A@9@>-@6/C?=D?#!5/C5FG,>4(H(;*HF,!"4G)2?!(,5.:G7"H(?:C&,,''G-'
@r2051
TGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCNGTACTGCGACCAGTCAGAGCCGGACGGCTTTGGCGGCACGGAGCCNCGCNTCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCNGCTCGGCGATGCGCTGTATGCCGGTATGGAACG
+
!5E-<6$'<1'F9/=-5.#>"D4D"5C#6'106"CA*=79(CB51+'D9:$E90B"B.'6)+>:7;FF)FF?'?->&H0:%7$-&';2FA"<;#!.:CCE'C@F0BB!(E'6-"3#D+2()F"=?@"3;;"A!6'9GG169!#<A?;/*F*<+.6%:"#9=%!8(<(;A;=A'G>9CCF4;$%9?DEA:'>4>$,4)/
@r2052
NNATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGNCAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCGA
+
%!@B@6903?(+@,+F?@"(8H8?ECC%&)41!#@<%F*9>D,41##(6"(D!;4*1:H+DD*,E?#A@$:1**">480+EB:;48B1EEG2!:F*(:A/=FF>')BD)B<D<(1<-3A45G&E4?'603!;+;0"*
@r2053
NAACTGGAAAGCAACGAAGTCCGTGTAAACGGAAACCAGTTTCTTG
+
$=8H#7=>D4,(/7&&D10D7<E?E,?=9"30,</EH*(D*74(0A
@r2054
ATGACNNCNNTTGNTAGANANATNAATGACCTCAGAACTCCNTCTGGATTTGTCTCTCAGAACNCTCGGTTGCCGCCGGGCGTTTTTNATTGGTGAGAATCGCAGCAACTTGTCGCGNCACTCGAGCCA
+
*''$'#!*#%)#)#"*&'*#))"!+$"#*+)+"%"()*&&(&*%*()'&$'+!""#!!+#)&+)*')$&!#"+!$''*'($"%!'+&%+#!+""!+*"+#(#)'!+#'(&%$$'%#"&!)&)%$#$"&(
@r2055
TGNTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGT
+
'#!++$)'&!%+)*"$"!'"#!$&'++*$%&'###(&'())(($)#'(&+#!+%'$'+$*%"))#%%$#!)!+'(')'$*("%%"#')+&)(%'*&((!(!%'$!#'"&'$$#!%#""#"$+!"*($)("+$&"#(()('$
@r2056
TGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTC
+
9+)C)@9);,+F!66H8C*&!/8F7?+,A=A"73>-5/'6#8!)7?HG:2=*<%7A"'B92B9>>0,
@r2057
NTTCTGNTGAAAAATCTCCGGTCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCT
+
#%((*%")*$))!#&'&)$$("(&*&++()&))(#&)*)#('&")$+#$!&#"&*!)('!$&*&'$&"*+"*+'!#")"'($&'
@r2058
CGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCA
+
!.%3C)@E"A:9=+*&$#,>B!?5938-;0=$BA?!E&E"3)&(.$CF'B9%3DE*!7A(7@?'@4*D0A:E*+
@r2059
ACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCC
+
/+;-F.F"B43B)9<;B+*F5$.9(6%D>%@47D!8>%!?/+:?4ED/761H=:
@r2060
CCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGNAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAA
+
9F,@%4A-?(*2)3:&"42E0'/#>%F"9-&06DH!CF%F16F$GD+@>.>H9EB6?:'F-H'9G6.9-E&:!<'EC0(>E=?>*<
@r2061
TAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGNCAGGGCTGTGGACAT
+
A7322;:CE/B83,D9G!9;:3)0H<<#@BH%4!ABCH:;(>?C4H!2=EB8"
@r2062
NCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTT
+
-%$:FH6%B<C>/7>H+&16:!./D#<+A&B1-44>05"&A;D7
@r2063
ACAAACACAAGCCTCTGACAGCGNGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAAT
+
<DE3'E;*<$6"?5"DAFG'3;,$@"=FF<H9;9D+2$$H/+AD2CGH?<%%+F*%6F078230'9(=%@;9D;!>0,869+E/94B$$)-B.>)C,35E!:2A/2C)6220DF<2H48%@8
@r2064
TGNTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGTAGAACTGCGGCAGGCCAGCGAGGCAGATCTC
+
")*+'$#!*&#"'!+'!&#)"#'+)')+%&+!&!&+%'#&&((()"&)+'$*++*++&'&('+&+!+%''
@r2065
TTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAANGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAAT
+
#295.FE57;>6'6<E1;$/2=7::*>!,3A4<0HE,F,4;F"#B"8E:?>"F;**/7$"(7'508F>"8-F9+?9B5-/1.0#,7.G%>'7'?.?6=4@+,@?;,@4%?,&-FC5!B,C5>8HG:5!H%'+?5"7<$9)@6$:<(!5:)=6&$A70B$%>C(*6+','097@H=)!
@r2066
CGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCG
+
"#.'!1:>'C982-@@A,=%AE%!&$7=294D7/+0'+.C#
@r2067
ACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTG
+
7-9H9HB7!$G!3'#<'?);?/7/&?@?F@287<8%89-,-(?)A37>9$5A8B@B=145>GB*3>
@r2068
TAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCT
+
!-,@-184+E!7*4))6/(E>(F'8>@1#488*(FAD.52(C=A@*D<'=9*,2-/$F4@;D0,%B(F01.%2>;/2!<7(/G05(?::%8A0*:H7#"8)B<?;&B!H.&G797500?(B!@A%E7:.055H3>D1/F?@%9>A0??<7<>F9.G,#H#3:>34001?8(G!FE-1F+!2;-"9"78@H>+<#,0C7"C#&<465@,6,&"0)%/H--=G!.!6#&3.+;$9&&.!">04
@r2069
CGGAAACGGATGGCGCNGTTTTTCCGGGACGTATCATGCTGGCCAACACCT
+
),.@'1,E'5;,!(;9.H$)A(6(/.4)F&GG?<!:613E,5698B00.-D
@r2070
GNTCAGCGCAGAGTTTGNACAGGTGGTGAACTGATGCAGGATATCAGGCAGGAAACACTGAATGAATGCTCCCGTGCGGAGCAGTC
+
,H:C6"(48'D6>%3-==H9?<DA:?D,;2GH2/4$$B7<>*@<$*B2"5400?<07630E9!,=5*85606,:$:+,&</A'B'B
@r2071
NGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATT
+
!&CH3',B>?B1C>?&<0A+#"@63750@70/1E//':;'(,7DDBDCB)H-7;<42(>E:#&%8G0H/.=8+&66'-$(/6'#/$B"G3'1"DE/A2F,1#2*-1/%9B4="-GGG-/&
@r2072
NGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTT
+
/F3:H-E63#A5>=)<!?%1)H;3+&:6#E0B4?"9%7":8"8A*;5)179$H2"#2@*H-4'"7)"8E44G?-6D,E+(97*F67*3
@r2073
CTCCTCTGCATCCGGTGTGGAGGTGGACAAGGTCGCTGAAGCCTTCNGGGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCANAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAG
+
A@!AC?F>&;0B((.)A.5(5*B<9@<=$79@C!&?.2@!2E/%E1<88<<-%A#&7:/4>5F"8&G4B.<04*/7+91$<GB?80:9H<*1918,>1293$>0D/6*.G+C#90-B(=GE*&*!$3!:+229#80$<=$
@r2074
TCTCTCCCGTNNNTNNCAGANNCGNGGAAANTNCNGCNNNNACCNTACNTGNNNNNACNTNNGTCGANTNNT
+
$!"#$$$"!$!$$$!"$!$"#!#"#!#$$#"$#$!$$##"#$!""!#$!"!$!!!!#!!#"!!!$#$"""!#
@r2075
GGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGT
+
3@'9C-#%3H@EH3?C>.F.=C95><=48F@)6&%745H73?6$E%2/*67-.DBG?+0)H26C,D:.FC.<(
@r2076
ANTTNNTGAGANTANNATATTAATCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACNTACAAAACCAATTTTAACATTACCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAANAGTCATTCCAACCANCTGCTCGTAGNAATGCCTNATTTTTTTCTACTGCAGGAATATNCCCGCCTCTTTCAATAANACTAAACNCCAACTTATAGTAACCCTTAANTT
+
#$*)"#*%)&($')(%*)("&)!)*+"+#*(('*)&"#*&"*!"'*"($!&+*#+!$(+'"%%%+&"$)*'###!+')+&)+&!&+!'%+'#%#'*+$$&*%$''#&!(++*(*!!*'(+!'&()*!()('*((''+"#')'')!%&)+(+*(%")'"%+&$!+'*)%+$++*'+#")"##*!'&*))))($++"(!!%!+*)*'%)&'"%$*#!#!'$$)!'+)*#+!!##!(#$)#&&("#*%#&#*+#%'"#!$(+!#%!&(!#!$+'*'&(&(((&)%')+$'+!(%$**+$()!!#!#"!%*%'
@r2077
AAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCNGGACTACAACTGCCA
+
/F4.D1D3*='-?<?6<!GEDE@+<-,5;#424&(B9G65(%F6CD37AE95A$G<+&E9;2#)&&=>"
@r2078
ATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCC
+
/+A!$2'A2FE>@.*&<0<=B5'/7&2,*%-,;*9*2+87;B"FC+,+6@H?67G2"&=4,C#A!D%F?+E,;31;-E$/'D-1F*;A*/2;4#7:71+!C##/A&F0CB55-4&<FC&7;%>9>HE,3!;C20:98,3A;G8)--:->.'--@F'(@.%2;!29#C:D*=)%@>F00"$<;CF7#;%&?0)71A,DF8CH&#)4A:-20,AB1C
@r2079
TGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCNGGGTATTGTTTGT
+
>(/=-/+F=0,*GBB2=#></*/)!4=6@*5(&?&=6?>&7451"5+B=,0<&79E1-4"2!@'#-(GA..8-")-0-+=+H8--@$ADG.:?6(.H>,14+"4(:,:A">1C4+1#0<+%HDG9D6>#D$@7H*!;;)F4(6$A*-4?%285E+?.?**!=$-
@r2080
TTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGT
+
.(74<FE$EBG3.83E6G+9:EB!5?-@7:'3)B;=5>@CFG?C'?:&2:;
@r2081
TTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCNTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGG
+
A@E7B11H1B1GG:&E!$D=?2/:F4,4H4":?6C(.DAB3*2!1BFB427$E.2>&;GEECF4$D76H%17,&3-!B&#9F(37090C00B(-+$4<!?G-*GHA,F",5DF7'%F84D
@r2082
GCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGAC
+
=9-1!4H7&B3<!C@8?AE,*73B88E$>(G0AD17#A5$&.1%AF!8G>;'$5BBH-=DF2
@r2083
TTTTTNTCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAANGTTTTCACTTAATAGNATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGT
+
#G*:G5D!4'@(G"C6'1*3"*+>#)D!(0;4-DB>(?9G?EC=B'0<9*D@<C+E-,A'&>HDH49@-1G526GD&-.*<#!(*4@)0369$E5G3%".*/>7($*5,;.(/6<8?A2,B<@=A<AC,'(+)7H7'6=E900?5H9;&87
@r2084
ACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTAN
+
C4G4#%$))2G'8=EA,/2>H*01?#8A:')448&12++)@3*>/<E><>=;1"<B'*A/4/6<F*<&/$!+):5A)F?#H1B4D:G-,-35B6*+@)8??-FB;:5*9;:$(:2)C??>$=@&E0.7#4'"AF$@;FDB2HB&'):D<2;%).44(&-*/409G&7&%6>C(4?.GF&:5-<7,FE7&86))2)!2E5D>,E@<G6F0;,*H,0/!?G5#HE-&;&">H@H-;,"!&/98!HC#-DE'75E&5+0<8
@r2085
ACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGNAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCNGCCGTACTGGATGCACTGGAG
+
<'@B='.%(7=$)(28A$C4:H.9BE9+C/$?*/5B56%%&)H,<C83==45)E1*&</*C%,D5%4C'/G1,?D5*8.(E>$$=(<G4*=FDA.2*,)<0FA+?=E'?*?G("%'>1EE.2$E6*F@1!6H
@r2086
GTCGTTTGATTACGGGACGAAAACAACAGGCAGTTNCGANTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCN
+
+:6+#5$28F)%02?0HH"#&$5;7$!H?%HA=5,"5B763/&=+G@8/D+@@HHG0=CD>+!)G4=3$G4C$&$D4E@/7B0,062B"G,?
@r2087
TGANNAGNANNCNNCCNNNNCNNNNAGNNATGNNNNGGNTNNGANNNTNAT
+
#"$!#$#"""!"#!"!!!"#"!$#$#$#"#$#!!#!!###"##$"#!$#$#
@r2088
AAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGNCATTAAATAAAGCACCAACGCCTGACTGCCCGATCCCCATCTTGTCTGCGACAGATTCCTNGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAANTTGCTNTAAGGCGACGTGCGTCCTCA
+
8760"G;52A'.=?"%)GC!A<:8@0-H=(.17.4/.H*'232E6?7:#$36C#*<8E1+BD/H"H:E!-+A!:)GC$A#H!>C6:7-F.0?"#@0=++>:C,,>659<40#'F#D&&"88C4."7<&#7*8;>E,A(7-D1A$:D2C1@-5GG(<90%$;/<H.4E?.?"12#9<<B76E-%EA$%$(D/-=)#A4G1.
@r2089
NCAGATCGGATGTGGTCGGNCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAA
+
+.G2>/B:>9H91"51&>9D162.0>&9C>@"0E6$A)C2*876:D>11:2E0-"C3*4H:A,8796
@r2090
AGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGNGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGT
+
$:&C0/>C&!H)BFG64B7&''>3=:1(-C3@00=+'>'H25?';!!56@!:<6>+B10A2'&>A615C2@?E)=4*5>315)GC%)*"?%H
@r2091
NAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCC
+
!('$('*(+%!'%%)'&+!#+(+$!'+*#'''#*)!)!'"*
@r2092
NGTCTNTNANACANACNNNCANNCNGCNNNNNNNNNCNANTNAGCGNTNTTCCTNCNNNTNNNANCTCNNCTNNNNNGTNNTNNNNNNCACNANCTNCTCANGANAGNANNANNNAANNNNGTNNATNNNNNCNGNNGNNTNNTGGAGCNNNAGGANTNCGNGTNANNTTCCANNNNNNNNCCNNACNTCNGNACNGN
+
$""$""#!$"#$##!#$!$"!##!!$##"#$!!!"#$#$!#""#!#""!"#!$!#$!!$#!"##$#!"!!!$$!!!!$$$!#$$$!"##"$##!#"$"!$!!"!!"#$!!!!#$"$$!#!#"$$!"$##!#!"""#!$"#$!""##$$$!$#$$$!!""$$$#$"$#"$$##"$"#"$""!#$"#!$"$#!""!#!#!
@r2093
GAAGATTCTTGCTCAATTGTTATCANCTATGCGCCGACCAGAACATCTTGCCGNTCAGCCAAACGTCTCTTCAGGCCACTGACT
+
B#!@$?AF4$C&,+10AFB>"?=,'G&()C9)<&,>;#@3*6/'6+,7<D%9$:4.BAFA'!HDE/">)+4,(D275+>#,0+B
@r2094
GAAAAACTGTTCCGGATCCGGGAGANGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTNCAGATCTGGAA
+
?=5:A'%60;A;>)/32D1(E=H26#*&H->(G?B(%(==7-/;HD+-'@?-,/92F0?<D73D,@#@0!A=9+?:@-856F:1)!''$CD%!;$B;D<+E5
@r2095
ATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAG
+
69*>>'?,%E*4-8)>$*EFA#4",$C/@G</E(B,G?E'?>C,83#/
@r2096
CATACGAGACACNCAGCCCGGCAGCGATATACCGCAGCAGNGACTGCTCAAATACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACG
+
01&2.CA#G@5-H@A9=G",0'8F+,$0'4@D5)(86;7#H2HEE*#1=D$,<39!508&0=E8H#@(0H-993H(B#G+..23+7727HCAE+:>0<!=2A"425%6!2=+@,A4%3;+!DB*95851A@95!E=,6*/;4>:-0,3841=36E80<C8<=2"
@r2097
GTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGA
+
;((=F07A%0$EB/:H+E:55:3H9E>(D&-6A)?(>#H52?-?C,,1$E=(8FH4
@r2098
AAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTA
+
C.<'4E6CF$H?+.74(B2GF+39/F>6F83'C!$21A19%%(7F"/":B.F,5"#,)>)7-"H#(%>""$F6<!89G/.F%):57*'D54"('=12=.*?3.41C"*%".37D7F(B92F6A2:6"4F(F,(+CD3F5!;A7&81#D!,5=8B17G3F.'5B;;C0'H*H)47BE4%(<5'.,3."BE(2.;8,D/DDF-A53>(*7)<!7(#&'5/:E5?)3/G@/40#B?1519B%4$9')!2GC3A&F@6,'>142;<#8,1H2@)1&(A#@9(+H1A-$19F.G;#01A340)5.511?<=-@=A)
@r2099
TGCGCAAACATCTGGCGGGTTGCGTCCAGCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTNNAGNGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGNCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTA
+
1$4CE;@=;<'C<"0);"?%8E*5/6'9E(H?>&C6BC/9((<+=(;8;1+&>#,<&:2(/:55+"7-+FF(3%!F/&+@)0H-!#)>+(#$G+.47-09)F%.FBB0!(C!;/==-!'F/#D+.4;D=73D#2/.(.0;&H6#A#"DG;":)=?&H<:#@240!?:<.7D2;1+8321%7D@#=DG$=+1'AHC9?H'8G+C<7*6):/0"28B>=#6C9G;0..G8@:!EC7>,5;B*AEG>.#?CEA*%6()5+!C=/'@9%A*1H#9A5*!.2C-.,@6#D0
@r2100
CGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCA
+
*ACHE3#<4?6!$0C.<012:E-63/80&A!7=<',F>,G-.4&#56$(>+8D,#*"FF#:&+
@r2101
TACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGGTGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGTAGCCGTTAAACAGATTG
+
=ABBH5<?!,$0:C,8>ECF0>C-)-(%%B+8E1=0;:=FB/2"F!28/F&447F'5"""'40DD=6,>>(+=7244BEB>@H=.5"?%E/%2&FE&38=$F<(5H='!H>1;
@r2102
TGTCATCGACGTTTTTATCCGGAAACTGCTGTCNGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTNCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATA
+
.G&*"8AC623C*9*>"0G%-C%%;(D*/-<5-%D'!7@1C@?6-G7!)C5+A7A%*1@+AH=(H@7+H)(!;3.)6'>?94G<%53"/0=BD2B)=G=,#$?C*>,C3)7;53=:DEA$%8"C/%>1,=3
@r2103
ANGTCANCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACC
+
"+#(+!$"(!$'+$%"$))')$&+$%$)(%'*!(##))&(*#&)%))&!")&+#*"'#
@r2104
NTCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACC
+
!4#D0!0H4,>&/:$6686,:).-#**>(DE+@3(#A+*1"2#)
@r2105
TACGCAACCAATACTATTNAGTGAAAACATTCCTAATATTTGACATAAATCATCAACA
+
*+"%%%+(!"%!#*'"('"&#%#&'!'**+')!##+"$"$(%)*!!+)+('"+#&%!)
@r2106
NTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCT
+
$5*%?;>)3.-&"9>0'2B/$9-?:662"30.=.;7(@<G),.33D5A
@r2107
CAACACAGGATCTCTCTTTNAAGTTACTCTCTATAACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGNGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAAC
+
"+"!!%(%+()"*%+$#(#"**''$'(&$"%*#*!&)("'**$+%(&"'&*#$#&)!$%$#("!*&'&$"#&)(!+)($)('!#'!'*)*#($*#)!!#*'!"+%&+!$'!"'#+"*)'%&%()%*$'+'))!%&)$'%#!!+"#+#("$'&*!*$)!+&'*)#+#'*&"+'
@r2108
GTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCANATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGC
+
A>B;0C%7E@)?7/'>5E(!9,'&-BC8<A;0H+)!+=5A:$F#*)9B)B<C5#=7?#C(>(-C<H3'0!@.$@/D;7+%E<A(=>'+3:77);"C;2('5H%7E-E582E;D$<=35"A>3E!H7)AGA'0->75%++2E>'15;?F/070/B
@r2109
TAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGT
+
BEB/;,#A874$7+F$<;A3A@G'%G)-4,?!0BE""A+/B87=
@r2110
NCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCAT
+
%B7H9<+%D9H.18A6<))%8-.3'??,D2<97("%#5F-E/3F)#%'F%*F&B21649@BCH)@-<A#"$*B7-&A"BDC98-4+E95D>D7&0=GD'95#H7=H
@r2111
ACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAG
+
B=1%>@7,#+D0?G,E#)))6?#"/=%,B!62,:3'1D>D;/;?:-E!66G,/..;'GD:GHHA,5B611+-,/,6FD"C;D!6(*G??=0G4H0><-%3$+,4B
@r2112
GCNAATCTTGCGAGCANTTGCAGTACCTTTGCCTTAGTATTTCCTTNAAGCTTTGCCACANCACGGTANTTCCCCGATACCTTGTGTGCA
+
D$:").3F7;%7,8%9C@02+5>@8*;<;@G?!30"B7@#$G+"='?HA+B.'?*5<8*/-:F%69#'E=GF>(#<F<:D,(@C?!);C>
@r2113
GTANCTNTCCTNANNCNNGNTCNNCNCNTNCNNAGNTNTACGTNTTANNNTGGNNNNNNTGNNNANTGNGANATTACANNCGANNCGCTNNCNNNTNCANTNNNTNNNNAAGCGCGCTGGNTTCTCCNNGANNCACATCNTNNANAAGTNATCNNG
+
$#!!#""!!$"#""#$""""$$#$""$!#$!$#""$"!$$$"$!""$#!!!##$!!$"!$#$"$$!"#"$!!#$$#!!!""$!##$#$!$!!"!$#!##!"#$"!"!$!$$#"$$"!$$##$!""!$#$##!"#!$""$$$"#!#$#!#!#!#"!#
@r2114
NGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTT
+
#BFCA/@;-D.A550CC2E?@CB5&C)%%-?B8"C9E;,!;3C)37H'<*B=7(AE8*%'CE+#8%03%#(4,=!/A@*'-(6D:CBB-+-
@r2115
CGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCAC
+
,&*#5&?.--A$33"E)79/6-0*3$=*)9H#:""!,9H=7?;@8<%G!:'9#;;-!$0$00HDH<
@r2116
ACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAA
+
B*E3HE!$>6.*4&3;975@5=A'+B"7"C;41"*D7)D0>$)<H-'+75>?B>H3
@r2117
GAGATTTGNCCGTNACTGCAGCAACGCCGTTCACGTTGATGGTCA
+
&%")!)#*"**&$%+#(!"!*$+!)%($)*$&)"'(%***"%""(
@r2118
GCCGCCACAAATTTTGGCTGCATCGACAGTTTTCNTCTGCCCAA
+
&%E8B#/!E73=C92*)A1.;"3!;8F(G7-(.:>(?='$BE/@
@r2119
GTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTA
+
=&%(0(.$58+.B-#5+";<!!@#H2BE+;=".?%<#+*('G23>;+1
@r2120
TCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTNAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTNCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGA
+
'C$('G,"E/""8A##$0C>?D.%D85/#58"G';+62D9/:G91E,&@8CF;=1C4CF(@=A!-6>9:-2)%+@247,,6EG7(%7<.H/&3-GB5'3-D,7@/B7503H3>!)2G2&A:$.=7B"403F!38'A*%B";8>/%<@8:H?*5*%#2&H3)>B@0D'>B,9"*A*>2D4:&)2:H)07H!1@8)-=)5(%*"5<:,5:A8,'F&0%1"&$9@,*'.C8E>66/FCF7<)/A&,-A2=(?-()3G98)@&*2+=.G4+G!$C3@1D8)@@15&:F>!F$"4B'3"DA28CG#$=4+2&D2F;43%.9?+DC*.3?<%.6?6)8$,(72C4
@r2121
GACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGNTAACATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCTAGGCTGGGTCTTTCCCGGNCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAG
+
:".G8)36(,#E2@4@9:C317A$84F"-+H9B-90!H/&?E89+67D!H?G/@'=+C5,CG>@-6"+=CD:5+4&'769<;/%@?1F+3-H*#*H$4#!?#*:+=.2")H7?8-7#57#*+>4.-F;1:,(-!%)!#+G"F=E5;?1&73/"<.'""&/"@A,/&')2#;57<B%@>*B95#3<=,@=9G;>A#1(<2,?G,=5D":H?135B"&0(58<:F'D!/'?,&"?$40!6-@/H?:.+G'?5F9
@r2122
GTATGCCCCTTACTGCTTCCTTTACCCATTCCNCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTG
+
H"FA7(46H-*BF*C)<2/8/#&%+H!1&..:491'H9$/#(7*H!<"4D"/"8<HH4052G%D1/H$E#!H!#A0C*4/E+D#?(F::BG>FB0D*!(>&%8@($>-"26="4(-F#D>*/;1%$"29B,DB18&2"F93,%+A@!H459".===+A-A?>4<A583,9A4"0"C?2).00*9B&?+7:7+&.BAFHD8!?B);",8(
@r2123
ATGCAGAGATTGCCATGGNACAGGCCGNGCGGTTGATATTGCCAAA
+
D47H+G+-DC?<30*9(4$E52C308HEC/;@<3G;<E.+3:<@A=
@r2124
AAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTT
+
/'B<%&/-=0-7,=*B*F":3=&C%091/;A334D(=,47-'8FFF;4G0(GHD/7G;0'4**>&!G73H:D3;#3,
@r2125
GCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAA
+
/,-4'>E2D%9*0((*C2;-?9%A+?:7#9.'?4E>/F-)101A$5><12;/-
@r2126
ATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGA
+
24$;$GG#':H-:5B<F4+&C..;/"A=;-,0D5*H)80#*B;0D<-%D&6+5H-=*$3C<&C51<!A67),79
@r2127
CNATANATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGC
+
%')($*+$&&"&%(%%!'+$&!(%+#)!(*%%!")&+"&'#&$"'#*+#+)+)+(*
@r2128
CGGTACGGTCAGAAAATACGTTNATGATANAGACGGNAAANTGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGNAAAT
+
+87)!FCDB&@..*3)#C%+:>H:$3)#6/B<%""1.%:FE(%71G"%8,0"*'H!>4;?C@,35,<(F'>?)BD&AC&(E@,A@38"*0.$-(2#=G"!.FE.9)0E#5@6?=/?%&#):G%=B87BDD@?
@r2129
NGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCA
+
&&?!B$;3B0:"6+&$D3860;2/G-"<?(F+76%E:-2EB54D.G3%9A:,=*9663(9;19#-:F.+<"AA:--E;E;+9!G.F4,@@(8'$+(7C
@r2130
NCNCGTNGCNNGGANNGAGAGCANAANTNNNNANGNNTTCNNNNGGNNNGNNAACCAGTN
+
"""#!"##!!$###!#$$"$#!#!!##$"!#!$!"$!"$"$$#!#"!#$""!""$$"##!
@r2131
ATGAAGCCGGGCGTTNCAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCA
+
6--321.:E0D>*$>3G0#CC&+!&%0CG--3?G@(A*#*=-=$=2.%)*"F*G4C7/77:<46&H9(%*!'7A?"A:>!8&/2A7&/"(9,5
@r2132
NTCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACA
+
"//%F9C9HE=G77!>,1:+@A80B?BF:';HBG4*.>0;-&>C%A,1GAA;*&>
@r2133
GNNTNTGGNTGCNTTTCCTTCTGTAAGAAAGGTGCNCTTTGNTNATGGCTATTCTCAGCGAGCTCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGAC
+
&&''!$%*(#))*#%#+(+*(++#'&#)""!)$$+'&!'*&!$&%)*$$!""&#$+*)("*!'#'''$"(!)%'+(")+$"('('$#%$)!)%+(!'$#*)''+$
@r2134
AATTCGATCTNCAGCACATCAGCAAAACGCCATTCACGCAGTACAGCAAATCNTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGC
+
:>8,9&D<-,>8H:3&)#E6D0GGG;!1:EE)D.>B=894(58)4>'C9&*2,,/=.->33?(G$D2AA,,%/G*<BD<,>%$2@"8<H("D+6D7F"*=#/,2)G
@r2135
GCCGTTCCGCTACANCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGANCTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGNCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAA
+
:2#A298;892FB.'@919A:@B4#0;"#9-5$B070@<?%<&G,7/8")E;/C'=06#=(=0/6264A(0&>70BG-/7+1@:0,9,D/G+F(@'38#B;B>2*?B%;(=C6&=/>6<6,$C9C=6;#/,H'>("+"F+2D0A:=>)B!1(C#<C<8)B%B/H:3=!7@<.,,9,E>;1&"A31)!):2'?:;*$1?)49$$.?H"F*3
@r2136
ACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCT
+
%/:-B<-%A3A1.=9EDG2#0H?"4%C7#,;8<F&@#6CG&#5#A27/<67A+&='A60130%B@:3EGE?@1F=$A&77)/!@4HG'''G/'EG<6-1!8!
@r2137
TGATGCGAAAAGCCGGGGGCTGACTGGCCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTAGTCCCGCTGNAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACT
+
",%!0G/.,+7A'>",@,9C4<).H9,8<!*?F<(*<("F?:G;-52"F8>)*%!3#B,A5=)A:?<3"&6'4#8B24%%")&9EF/8)*?C7%0&'+A',?5/E)D-79;#;D6D?98@+$)'&+=/.-<G7>2*78.%=-&&7??69A3:<C25C1F=%%'&/-+9;220)#B>!>>E26F9!HHF&,'"2C=7H<C1?C=(&/,/=)"3:='$-?,@-%3<B9,//#06D(%!;#$67&98<%2#-(F6;GD=(52F'1.')>*A*C<+(5D-:B6">>75>H4:,D$;+"?;:6%B
@r2138
TAAGCACTTATTCATTAATACATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTT
+
4$@>G6%"4).D?B891)+5G28>=6459/$E-F733='"552=D3G,;3HD@6/0/8>')
@r2139
TGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAG
+
H?*(D$H?1AD8#2F,?;GC7.'#?8:=&?2G/7615=$6@+,*E#9<
@r2140
CCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCG
+
H!:02(7D:7?BH.?.$A,0(3B>;<;C%&%4D9*A6;9=/'@$F><?%D!=A+B%BDG/"'F(&/9?+3D2<"E5+()#F?71?2,60D.E'94D!+:
@r2141
CTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATNTTTCCTGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAANACTATGAACAATTGAGTCATAGNACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTNTTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTT
+
-*$H(&2DD<1!)%?>'A'AA=216?E84@$3D;(-.#B5D.C60.5F5*;'F3.D?:*$H41"80:,7C:(=HD-H;9:4ED207*"!=73%#5<;-433)%(>/*<>C?/0>DE29&:4=?>0F"%:9'+<7%;#+20<E@F:5:!#"38=<B1*BG;!>E%G;88#!D6>ED8-:=#<1*6G6F>/2'E4%*H&<F./%B1.<EHH$1C&5E67B9F9B%'"4+H1,$7G44(&//7,GB7;43"12AFE5=5.G&?'%-2A6&;H;3,10./+B3<.06BHG1E.;1:),B%9G6DD'H#8F'549&=>
@r2142
ACCGGGCAACGAGTTGNTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATG
+
33E,?#G/'0EB*H%AG;9$>:1E3+C8(G(9()'+D#"7!#=F;+"$!:@!06&
@r2143
ATCGCCGGAACGCTGCAACTGAGCAACATACGCAATTTGCTCCGCCGCCACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGNCGTCGGGTCTATGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGAC
+
@6)<A59%@G(8"%*@%/%:1-@8GH!:,%')$C7HG$E$B$8B878%?FEB26%'*)%+E+AHA*<!;6(/<G2@$@FB1#:(0$58-%5$2-E2H3:'2%<C/8;3E73F-2.:C6%54+>@#<A9F$5/?,'@'.G"4;?&C)"C&<-,+%3<"<,BD-A7D#-?+"<42E85!6B
@r2144
TGCACACAAGGTATCGGGGAAATACCNTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCT
+
3@F<>.%7B23,$#"1G$,&?B/1"(*":A?:%*0=!#F#B8<HDCH0&"/CC+H#$!>/+(?20>03C4<(.GD;/F
@r2145
TCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTNTCACTTTCCAGCGGAAGGTCTTCATCGT
+
.-F,(75=D#B65'G;?EB/1#59!H8*$,(*#(CH"8D*F0*!!8+'DB1(.36?-G4,6-943=@B%C>;-+,F?GH>,+)73-8:+B(3.0=(+G8F>17@.G(00+G2$!?2'E=#@;0!49>@G"*;:H<+<#95/!.7@,H?E()!9E(1;0*D:?,D
@r2146
AGGGAAGCACTTGAGCGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTC
+
+/F62E/?*!1*7'5F?3@;&;52+6/2-D;G6#@C/)C&7%DAG(/=@80"H,E*@$:5E=!@&C%0@%+/#G!EF<A$;06#43!36.()H%05?4D!G*;;/E6%#07$5@77'(7+#-<06<C1<3?,G$"29/7@#=(";
@r2147
ACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAG
+
&<!@2@E&?EB'A4C+A#C#H>'%'%'E(*9F<B@5B9A/A'(E<,3
@r2148
TCTCCGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGG
+
!2"<B'77(->'-!'!%>FDD2&*7<#3/*"2-3C"=?009(9:1)+91+)/A/4F!613+'D@&7461%%-*1*79?%#3>)3=5F82B5.9A5<6+,E'=#B-C8F'D3
@r2149
CCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACAGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGNCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCACCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACA
+
)65?D<>%$&'&!/@H>:5DFB)9-4E*$$*51/D"':"94*2.<"96*G$$1"A'(,@%!2*=;'57>HHF?A<F!2&F#!1%D,&?BG8#F<903AD8)"=C:5!4#)2/;B<6*D-+&E00F&3/?=55DA*8$C@F""$*!-1@66:"26%%*A).(D>:<--?<H(-/6<*32.9$C5F'080F;%09GH'-BE.5!9),3A/*:>
@r2150
NTCNCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTNGGGGACGAAAACCACATCGTCGATTGATTANNGGACGAAAACAACAGG
+
%D+8/9=#-D:)=:(-61%871H-'>H"8>/$4*4$%&!7>@,9;-2=8F88:36$B0#&,<*D7'53D7D3:'0F<$@"084:2!A5%)DC)!>!3@!B6D$*<9"9,.HEB%++:D*$9+,&0D8':(;2C:=)?0=)HD>2,F59'09E->97C6C7B$B.2$;/#@*A5G>.F;'0A&
@r2151
ACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGANTCTTTTGCGATTGGCTTGGGTTTATTTCTGGTGCGTTTCNTTGGAAGGTATTT
+
<4H9.9;2""!BC9D<*-<G/G8!$#6G??$EH"974-24.!)5678!1)<'>2#(##8;,@!34/>+GG*-0EE&<5?17?B%46,G,1+4'90D)G%<38*0(2>A3(1A9&
@r2152
TCAGCGAGGACGGATATCCTGGCTGGATGCCGCANAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAG
+
(/#.(<.?A73>#FC2>$?(.-@8,(+.:&)C>*?H65:B-9(C6>E/%+.**E6/'7:F'E""@:<EC.'&AFB#>>(HE.725G30&46"=685/*/,1$$H3>&CB.*F5FG&*,(><A.H)423<'D8<@E?,0(E!7(B2C:":A.7EH)%@>&@G
@r2153
AGGTNNGNCATTCCNNCTGNANCGANTCCNGNNNANCTNN
+
$$"!#!!"#"!"!""!#$"!$#$$#!#!$##$$$"!"###
@r2154
NNCGNACNNGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGNAGTTCTGTACCGGTTTTCCTGTGCCGTCTT
+
""#$""!%"+)+)$"+)%*+%#')")*+&'+*"#)(+#"'*)')&#%$$!)#!#)%)*%$'+&%'!%%(&%+#('$'&'"#$'+"&!*)#'$#**&!)!)'$$)*(!*&+"'+'%##$+*%!#$"'!!&##%**&()*'(!+#%*!(&+"+)+'#&()'!(
@r2155
NTTGCGGCGGCACCAGGCACNGCCGTTTNGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACANCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGGGATGACAACTTC
+
!+'!"$*##!&''#%)&$$#()$'%%%'((("&&+'!$*'+*$%!'&%%&!%$+*$(#(&$!#(&&!$$'!*%+')(()&**&!)%'+)("#&%"+(($%&(!!(!&"'+*&'#)')+%*)(++%'&!###+#()+&'+'!'*#''')!$
@r2156
CGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGA
+
$E;B.@BH?"C*!&3<*GC6+HB)5"4*"D2F8:3&#/9EA??41"/>".+&26,8C)9"<@
@r2157
TTCCCGTGGCGGCTCCACCTCTGAATTNACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGANCCTCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCT
+
/'%(G(<3.0B$%>G-8@-($,"%,)+"?6?D'03(.A8+03'#(&)*+#F/$/$5)';(G-B5,G?&<>#G!0E+>B-"4%-%+0%BA(8,2+F.5.8#E.527AED#7:3*G(0*&!63A3-$>*B88-?1-=>=#-AF8.E*:*))=+#!+%C#726.<+&"@+9F2E:200><9%),
@r2158
AGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAAT
+
27AF83$@/#7/F2#F=>B7;G<'CG7;;'5D34//&?'D?18?/1=)<E$$>!8B+@+DA8EH3!97'=A5E98?*(A#'>2*$79C%C>%"-33&&&1@-"E*"86684'3C0:B%9<(5$(&>--9G@-2<%93$/'B4'86CF">@
@r2159
GAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACANTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGGCA
+
=@/4=<0*H"8-8903?6,8>8/='*1>,25(-=#EB2G&8$!5,H=C+3;,HH/5>%D@+@978H*!=?"4<4,46E8"&,F'A9/+!H=B.H?&#@/+"0-1C2-,&%"'$?D<2
@r2160
TACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAANGGGATTAACGTGAAGTACCGTTATGAGCTG
+
7$0H!2G!"?;#C7926@/H+1>7F&=+<1-"B=H*C*B9;''(3,?+H<B='+<%0-@1+9C.6<,>(&$63)#2/-DED@>,@?.,9+A80.'?-A$/82.72-*>0C&;*7:
@r2161
NCNNGTCGNNTCCNTTCNTGNCNGAGNGTANNNTAANTACAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACC
+
&$""$(")&#&&%$'"**)'*$")%'!$(%&!$%($#++'')*%"$'(%"$$&#"+"#($')(#'"+#'))"*%("!$+!'**#$$%"!++)"!"'!$!$&$*%*)#""*"(#&"&*""+"!*$+)(&*+"$&''#$&&(#%!"*#("#'')(+&)"*"#&"'"*$""+((&#+$&
@r2162
AGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCT
+
/3.C>A32,5C@-$+?1CG.$.?CB""/:?$H7-2)E33*!'B)@?G/9!;59!+0(<(!43>/4%$9;$
@r2163
CGGCGCTGCGCATNAGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGTCGAGCCTGCAGG
+
"'+.737;7H$:=D@==0&989;'"/6B9;FG"90*)=C6%=>/G#6C:6&).!$)A'#<;!=A4=8
@r2164
NCNNNTNCGGGGANTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACT
+
$&!""(&+*(%!!"'*'"%"$&'$(*"!*'*&*""'&'*(&$*&$*)&)&!("+%#!#*$*'#(!'")+'$'%%"'''#"+&%%))(!"**%)('%")*'!)!(+(*%&((*!$+$!+#+&#*$'&+!)&**#!'(&)()*%%%#+%)*'%'
@r2165
ATGTAGTGGCGGAANAGGAGATAGCAAATGCTTACGATAACGTAA
+
2H=<+(65#6"-@/$2>-+3;C%)<,7G,0AH;D*B4@BD#0(<:
@r2166
GATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGACTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTCCGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTT
+
&++)#))*))$('!'$*")$'"#$*#*(((*)&+#"('#)&'""&)%!("&&('!"$$*)%($&"#()+'(++)'#'++$!$*)%)'%(%")+*%(%$!''%+(*!*#$'!&&!$)$&+"&%)"'&((#&"$*+#("!&("%(*$"&%%')#'"&#!!+"#&%+"!&!#%"**#"%*+&&""%%(#$!)%(#$%!)((%&!$$&$')&#"++($+!!$+)!%*&"**&(&($'())*'!$#!+)&*(#)$$*)&*('$(!#+$("!'&$)*((""
@r2167
AGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGG
+
)6>?.D5>4?81BH0H=.+4+8,&E<6!8&"5+$E.!:HE!<3B#%G&8D);&*EB'6;C07?1G)D6".(6>E-C8$F83?G
@r2168
TTCTTTGCTCGTCATAAACTTCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGNGGTGCCGGTG
+
D3$<)0*B7@:>)!0%#+81();+9F%D4F$<G?)/*E528*;139?FD-5'A*1GA)8;(,(?/?6?95F10(?D+&(/="2)$D=:&2!=B5+
@r2169
TCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGATTG
+
(6,19("BB)/F*(5FE>?DE*.1<+?7>-1=9)+9@H!-%&1H3C=0#@4@.D#>.-2F;$3D&>-'?1F%5*
@r2170
AAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATC
+
+$&!!#%"#)#*$""$#$!()(!)!$#$**(+$$'+#))#'&&!'+!!"&&&'+)$!%*''%$!+!)+&!(%"(')!))*#&($#)('!!!$##
@r2171
TGCAAAATGGAATTTCGCNGCAGCGTCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTNCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCNGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCNGCG
+
6%H)>C$%?4"5D*ECF)0@1HHH$:D8%9%+:*)"$.>DD.(3&4"2DAC(5,"407125/3A$)G-=60>/*@73@-"AE$$'2';14B'CH@*(A@>C0+9:/9>6/?!'*83B"@$3G9.F@48+?/-E3=-F!7GAF.%8)C<#*C@F(B4CF+8%%@<:/,F!>B2D<FDA08F#)(@B/:8.6*8E(7C#*C8.(FE&,%:1G-,-E&)%-$9&%%/77/A*#;(D25)@H-$%5;>+D5:?2D!7+!*5
@r2172
CGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGG
+
@A=H9E*<4'$1@<):@'F;0>55<G77BC#*:AFHG6@>;537>G7@.2$56?0E9(3G+B/;.B9!>2D:'78CDB+??A
@r2173
GNACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTNGAGGCCGTCGGTCGGGCGNGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATGTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCCGCAGACTGGA
+
%!"&+$"$*+("+"+!!)(#$*'()%'$"$$&(!()#%(%&")!$"$!'*+'*++$)"*)&#("#"&$!%("(%!$)('#"#&$''((')%)+#(%)#!#!"$!!%"##'&%&)&*)(!$%$'&&!+$&+*%%')%+&&!"$+%&!(%!('&#(+&'%'&'$**!)'%#(#(&&)*#)#$')#%%$'+'*'+*%$)*%##(*''!&'+'"!!+$&)*&%'&!'+"#$!
@r2174
TNNCNNGCGGNNTCGACNNNGGNTGNNNCNNTNNTCNNNAACNTNGAGNNGANAANANCNTCGATTNGNCNNTANNNCC
+
""#!!"$$$##""""!""$!#"""###"###!"!!!""!#""$$!$#""!""""#!!!$!$"###!!$!!"$!#!"!$!
@r2175
TTGAGTTGCCCTGATACCAGGCATACGCCAGCGCNCCGGTCG
+
?2+D#:7?&1H8)!,4!.<@(EF*%B3$B,856?3H'<?4E>
@r2176
TACCCAAAACNTGCTGTCGCGTTTCCATCGGCTGATATGCGAGGNTGGACAATCAAGGGNAAACCCGCCAACGGT
+
(&&+!+)$!*+#+%$%%&&$(&+($)"+$(#!&%'#(!)++$+%&%$#*$"#&%**#$"*!"""+")%+)&!$'+
@r2177
TGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTT
+
)4E<+/+$H7C9%,"B8:8:(?A.2$))"?0)5F/'*954
@r2178
GCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAA
+
(>9=6>E)!;B='.)@F&"???*BH7HG';.?&"7EF53D/?<"&EB,A.4>>-8H+/C33@)8&3/E',=5E/
@r2179
ATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGT
+
+!&")#*+**$*)(&)+$+#$'*!!%#"*('#("$)!%$))&'(+#'(
@r2180
NNNTGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTNGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGC
+
!!"(+""!$)%""#("+%#+*#"+$*'$*"&%(!!#'$*+($#)#!#*+$%&#(!)#(#"#')"#'#%%)++'+&*(&"('$&')'!)$))+%"+)+*'#$#$(#%&(
@r2181
GCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTT
+
>49=#6CF800,E%<3H!FG*!,($)!E)9,E05$E=A0'=E(3H.$""+.A&*?CG>@6?@,/D7H@.6/929:$(G$E>1/1:=20=>8@4,<9,5/$>6)?0"48&06HH<($)4E,4;>8!!&#,BG8)H.;%$98BG)52</'7!5.8+!!G+,DG*5:;8D97
@r2182
TTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGC
+
(<>98/G0=2E1?6@DA!(6"(@/5,,C:>?B7/++;5580H-&8D-23F/<%=$
@r2183
CGNTNNACAACNCTGGCATCTTCTTACTGGTTATGCAGCTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGNGGCTTTGTGCTTCTCT
+
&($&()&)''!&&#&!&((+&#)+'')!+&")'++$#++"%$'*'("!'+%(!)#('$$$'""(&($)(#!&"'')')&'(+#&!!%")+'#$(*
@r2184
AAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAANCATGCATTCCGATTGCAGCTTGCATCCATTGC
+
8;!&/B!C?!.6=2,6*H:6;*=A#'"6:G7:;@*9;#:F(F:43%5++5+2%4%!0E="**0CA3&-&B)"0A+3&05#""'3#,-!.$*,6HBG$+ECFHC6'.34!,(-;!0EFG2>FA,/;!(7D#C2!B0F:#8=13./E67;=-$6!+8&";&;B*3(#.)=
@r2185
NNNANCTAACNATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAA
+
#$"$!(%*(%)+*$$(*+!$'&#'*!)'*&"("'"++*%"#"'#+(!#"(!!%((('#)#!)(%&+((%!$($*+#$+
@r2186
NTGTTTGANCCATTCTTTGGGACTCCTGGCTGATTAAGTATGT
+
!6>$#6B,'@),F"!3<36B282#('EG9,=89G&*26>;C2D
@r2187
ACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACNCCGCATCCGTCAGGCTGCTGATNCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGG
+
8G:1:-7+?"2G2,C7E4:(*)$D<36&7;3=<-7/9!DFHA?3D-<EG!8-%9B9AF>0,:@1!:D<A,9:2BE0$80E5H/621@)/"G4(;6%0EC76G/*&+GH,B?1<7<4*-#C6B6$/5FFGC::1,5?/:,9(>A.6%+G(9G;7H,6)'6.:C$'4;0%CF/@A,9D?F5C*)+?%,6+D1E*&$13&2E,9:!4D$H001$=.+9?;2$&3?3"&'HD"!>2?;//<09+6C"E1!3A,-H4HHH
@r2188
TTNCGTTTCTCGTTAAGCTTTTTTATACNAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACNGGTCAATATCAGTNAAAATAAAATCAT
+
B#2-B9EFD&*B0<-2$B:;G'D,6)9<4'18H+),.@)7DG45,$F&?;G!#C60*$&,E#EH#3)$,;!<31?,+9->32//C1.&!;>%A?+(A;="?6-D0
@r2189
TCGACAAGNACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTC
+
1")-C&&F<)"B3&-#&,GA/!(@9B+%=!7DC,6238+@8#C!;EH!&:&E2=(.,,D.
@r2190
ANCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGNGTGTGGATGAGGCCATNAATAAAACCTATACCCGCCGGAATGGTGCAGAAAT
+
$#:8D2B,@@,;5E1$A#8A6%@-?%-7(#6)%17&B5447'92)-;<92>D2*&@(,)<9,D$43"?DE!@*4,;1)$?359!@#%1?B1:2$A>>,,F
@r2191
ACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGAATGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGG
+
)*=8131B:70*=?:.-:;;"&9+'!/"(-%/@A<2=4A-%@CC4?>"=H2A05#)7A$3;&,;&7!;*!$(H23G,G@8'*G6*2'>C+D#>6+=!/>6/:$#-A.@8
@r2192
NAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGC
+
$?A+!C0'>&.@:G6'#(EH75*:G->,+:&8EGC.";%A,6A2
@r2193
NAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCGTAAAACTCTC
+
$*A+/3!"/:/A-,GA+.H,&GE#-%/),'98$DD*%F1+F37,)5A6&3!5AC&()*9:/#&:B@2)@%&5:(H>#&>BC(+9'@1!04/3+3?#D5!
@r2194
TATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTAT
+
/&B"%+$<9<'F7D%=(9G1D999E:C;D1BFEG84<HG9E8"12
@r2195
CGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGT
+
#G7/0*28F3%.4>$6$A@=H?5;6!*1!#8A<./(($/3<H4>?##F;
@r2196
CTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCT
+
(2F%%9A>3',$<4;A$#82EB:>@=$/@2AA2F:/$25#*+=2@$"0'';#>/+E&HA'@$$5@$0H..5)3+=HB0<+@#H!
@r2197
ATCCACCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAA
+
BD6=D!'BF@>7H6"EC0A#>&!;HE)90"4&/%DGH/ED.>(.=
@r2198
TCGTCTNGAACTGATGGTGGAAGAGGTGGCACGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAN
+
E30-G;,0+'(*#G2)C8%32D6#"@D!B(+-+:-E9@.%&.@=&>?EBG.+96;18!6%G!15$3=E6)-69>1
@r2199
AGTGTCTNGNGNCANAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATA
+
*%'#"!$""#&!$&+!#'&+*(*)%#!&#)*'"$&'!""'(*$$'$$+&&+$#(**!&"+#!""
@r2200
CGCTTCATACGCGGTTCATAGTTGGCAANGTACCAGGCATTTTTTC
+
<2/2#2))48G//%B?3/$<D;=+2F6!9@(-@!,$',#)&#,0@)
@r2201
GCTGAATACAGCGGATGGGAGCTGAAGCTGCCGACTCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCC
+
7'H$/B#6":%!8<&/?-D4:#$A'*@0$=*71D*'="1D38(/=D2"*0G$)6-3#+FCG86D<9E.68
@r2202
CACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATG
+
**+9C;=F):=452!'(B:&.(?/$&H7?$(6@?$!+CH7.@.)?.C;8!:>.%8-)/)>8?#%,
@r2203
ATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTAGCGCATACCAAT
+
)262;,(1H*91($+#C/)-)E8$40*"6AD-0$(3*D=;*,1>.H+'G%5A9?3?.**F%1#:@7?/&
@r2204
CAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGGGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCATTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAG
+
$385?=)G;/B&8="577#0&7*3;C'=.?,("2=6@%/G60>@E1=.%:&-DD/-)B$C53:@!'G@3CE7<G$-C?H,F22#'C<F+<B"8'<9=#G7"C:+#3>36-/B--.10-)7H3@C2*"A1A%.E@5:GG;B/,$;!>:8!/'F#<&;7?$;D$1E9:9(E<:&:7#+&/"<B(D%/+2:-B)A7844?/8E6?.>%A+(+*G@FF;E7,!H=FC=:B7<"73(?D7">>D;
@r2205
TGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGT
+
7("'?=:,&,40FBE(0D/,-H!=B1F**@*6":&&20?5&-9H;>)F&G>8FCC.-6(6';.*+?<!A10"A"1
@r2206
CGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGACAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCGTTCAAGAACAGCAA
+
3$"00:4&6=+!<'=C8%HEH35-;6A@09B%,C0)6"#?E,1>115%G,8,7H2+'G<($FB66-D$E!9'55.70.("<=70#)H5$1?D9<04"D*5A<5-6'%,&@7!*)$$<BA/F?.0B2:2</&,E/FF!?#!0B=F-.5-G=4#(&*B-;1BE)(5'3(1/'9F.=?55,&E=%,D8,@@@205&:3#D
@r2207
TATCGAAGCGGAGAACATCAACGNCTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTNACCAATATTCGAATTGAAGAACTGANAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGAAATTGCGGAGACTTTGCGATGTACTTGACACTT
+
:3%$<5<CB28C<:*2!?,?!%-F>!9;C56F1+!">(?+>=-.B.H:1A4'+CA!)84"A=3B+G%%:#$!54!84%#6))"FF9966+'$@'46A6)')12-;*&B467A,0=>=*5(*%F!.CD.9HE+(>"E:@4(,)"@!"/7%':;/67:=0#B9-,8'D<","%B
@r2208
ACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCT
+
;5?E&BF8;A98-8(G%6>8-*C8*-31"*(,C7%=F21%0)@
@r2209
GCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCNGCA
+
07)7!,0E"E3156"4(F:(B2)"#29D2;#?E*/.D=-1":E(5?4@*5
@r2210
CTGACAGATGTTTTAATCGGGAAAGGAATGTCATTAAGCA
+
#'+%$**&&"&''("+'()!++$%!!""#$+$(+"$#''&
@r2211
ANGATGACACNATANTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCNCCACCGTGGTGCTGTTACGTCTGGCTTTCAGC
+
')&()())#))%*$%+$'*$!#!%+*)!"%"$*#($++$"(%#)%&#)!(($!''('&"!*$"!))&)!)+$(')$%%+##)%+$#+!"$!&!*$'(*!'!(++#'+!#!(!!#&(&
@r2212
TCCGGCGCCTGTTNATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGT
+
/F5<)3./$ADAF:?5!4&<&/?1/=-+<94)/F;FDBB5@$/'&C!"==BF=(DC$:C1B;
@r2213
NTGNAGCNCAGNGCTTTCNCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCTNTCCGTGG
+
##*!"*&!!%$(((#$)!%++'"&)*(#!'''$+%!$)))"))""+(&'*%$$*'!+"%"$!'%(&&$"$&!++&$("$%(+*+&!!(!+#))!#&&'$#&%)%&!'+
@r2214
AAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGG
+
*0'5:G;,1(?#!=&-*<1;;H#!F6A;F7<H(.5,3B0G$+)B95C8.
@r2215
TGNNNCAGTTCGTCGATGGGTTCGGGAATACAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCNGTAACAGGTGGCCTTTTGAA
+
')!%!(++**+"'*($!'"#($()'**&)+)!)*%&!+'!##+)(*)'(*)&+$'"+$(&*"#+($+("')+')($+((*)+!&)%$((%'+)&!+*+!#+)%$"*!)$)!!$%+!*)*'&%#&!#$&(%"(
@r2216
AGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCANTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGANTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATC
+
BA%"G1-90)@+H:D0&-"2)E4FGC,3<*6""?0A?B!C*.B*D&*=92'+A'/<D)!9--?%1H@:*#/?85"!<B!%"3E$%GE+HB2D";15DC+84"'#4H1#&$?6+(&(AHD58).F>2-
@r2217
NGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCNGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCGAACATCCACTCTGCGNCG
+
!:68E:-%=,=3>8<0:%2#6G=9?F#B=+")4(<F50559="!5!:C422576":?9$;6<A38:)=0:<"/;61=+8@:+/.8+.B3$D(.F,+3?0G,='6E;G3!C*$?*C=5(C3&.04DC)2)EC)#"7+'!&@>?/,#.<&
@r2218
TTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCG
+
F.'(5/D(2!.0G!A9:40FG@"?<>8#@513&F+;H?;:1(C(>,.9BH9))4#=0::F
@r2219
ATTTGTGNCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGNTGCAGGATAATGTCCGGTG
+
-D&:9E*4544*893"!?31'9BA7.?F6$93!G.,B;2.:77,?EFD!1!9-4!/"F&)A).H*8:9H-'.5*.
@r2220
GCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCG
+
<*D(,F:1/H*C:'2=36=8A.#*98'2745+4<%E;D#@!AB=*H+8$2>
@r2221
GCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATAAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAAT
+
+B:E-A;G.FC=718CD9=1@*%07>2"1F+%A<-E)=>66.B3&!G569G4G%$3)7;@@DFHB:7#A*)::?.1)BB7%G)=($AGD&6!))E-A&E@8(8996G-0(6*!4+;HD/=!.+69C/&C&DD(H@*/5C@;$->.F,7BA,$BGB'$72""7H@$9%39:C94"EA.)357'*+$**F5/A+.G69B1760%5C=&E5C=(
@r2222
NNNANNNNNNACNNNNNNNTNACNANTTNAANANACCCNNNANCGNTAGGNTNNNACAGNTNNANNNNNCTNNACNGANNACNCNATNGGNCNG
+
!$$$!"!"$"!"!"!#"#"##$"$"#"$""""!!#$!"$!""!#$!$"!"##!###"#"$"""""#""!"#""$"$"""!$"!$!$!$""#$"#
@r2223
ATCCTCGGCAAACTCTTTCCATNCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGNGATGACTG
+
.="5"7:@&B=C1DE,EA'4;8=&!<07,&49=F:@<;=&/A1?$@9F%<FC>/C1C=?1F2(H+F"208BBA,.97G<#;'9%@A+4C'"7%&"=4144
@r2224
CCCTTCTTCAGGGCTTAATTNTAAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGC
+
HG:/*,0(F!:4,(FH-%"'(>*#>2E=;$"4(.C/7.;40*,FG5"$E2;H,*?&60C
@r2225
TTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGANAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGANTGTGGCGATGCGATA
+
%@*01?,A=0()G%D)D@'):10>*0//?0#;H5>2%4.D11AH<6&/H-9/7371,75C=:H42.5@0D<E.H*9>;%B/=2-H(&%@86.@'3/-G4";C/:25?#)F&03/D11E7'!E1*:=2C:(53(;66/&C3!H*A+"!49*GE/G;B?2$:HBC09F-,%G.C.<)&2%<D(A
@r2226
ATGCCCAGCGCCTGTTTCTTAATCTCCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCNCCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGNTCAAAAGGGTGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCNAGTCCACACTGCTN
+
1>..0>?&27"H87+'!(8:2(2+::B/1#H,2.;,A40,D5<=;#!.1;07A.C4?+6D28F3C2:D$5==8D##:8C*;D"(/+3C9,;."?#F#>6?B7@#A(E8$FG)33.+2%E*E0CE8F)!+3<,4AG@11..@2#.'*@A.C8%43G%'4G.A&7&E8+=',/=)C@;3?'0;!#814"D2B:$EG37$(A32H>(.<&;$7C658G*F)4ED?H1BC&E0*5#AC,)#@E="5//GH"92,.*"C)-B3C<"!1'!!5A=3B3?"?&/!<1E"A##'58&5@8=1;3<:?:6".8=/+*B??)<C;!-CF4A,24?C(F9+;4E<!-%?8FC?<*=('+/-H)G88.1
@r2227
CTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGG
+
%&@:B4;*;9$>H-@1*@:9B#!?7.HAC6B!,;$6H0%1%0H2!D596>09D5*9)"G9A+F74?*>@5;
@r2228
GGTGGGCTAACGATATCCGCCTNATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCA
+
4#4;)140'"#-G8#;5*+3HH#%DB%-2681'D4H48:6BB@123+D:*+83@"'8=G925A%;19+A23CE6++.05D(.?/@03D/34H1@@)F4"9-D,&&-/$'$/7*#5G:33F<8F
@r2229
TCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGANGTTGAGCAAACTTATCGCTTATCTGCTTCTCATTGAGTCTTGCAGACAAACTGCGCAACTCGTGAAANGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTT
+
.)(&3%,G(,AB2?<.'=;4$>$A%$:*!:%3>B83G?5+A?F9*2@,D35=/;?'4%#;(64G$H5=F#?A$.11('?7"&(G':.;1C#7#@'"6+A5'.=&A(+"-6'.=64+'#,-8G9)5'#C8+8%%2A)7?/E<F@-H!GB3*'&8,;(?9>0G.$H&54=0F:.G#2206;(D-3&;1)"'9H'0-0%<D"9F":!(4:"91)
@r2230
GCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTT
+
9+:8&#/-.;7D"721H@E.?B#HHEF.8,0@8D5>H<-0:-0!2=99,F.?/1>55?9H&5?&/#6"B*-(,9;02)GB&H$05?:%/G@1#'C538B?">#F'=(3:4G:8+GC"D759!:H**B/B!?68!@FE>"?11CH(6""&"!@"<0FC+7B;HA,7D
@r2231
NCCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAA
+
&4F)19-;.B*A%F90.';B3$;2-7B$.24C;*/6-H#>?@*A8BH.A'3D>,@2D*#(B>.GB<>&-.*)),F*1G@"8+>3!:3/DB=GC;3/AGGFC?CA>6D?-?&7+)9@"33;<1B()F*'64#1+$"&G;>&68;/-*@1&,=D+<#,857$<,#11.9;3B"))"=7H'2-(7")9-@=)).D$$/8@B%?!58"GF997@(2C"=+.
@r2232
GGGAAGGGCTNTACCTCTTCCGCATAAACGCTTCCATCAGC
+
.:8F@DHH/:*)@F7$338C;)?*@/,B,044234+/;2DG
@r2233
TTCATAAGTGTTAACTTCCGCNCNTCGCTCATAACAGACATTCACTACAGTTATGGCGGAA
+
)1D8<#=?0BF8%;D".@3$=E03.F2,;&H*8?5@!A2=$4:",%-B9/(4!:7)G"$+A
@r2234
TGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTG
+
D;A+/)$.$4C$=!DA<'%"C0A<(:<76$+3%A-8C/5/;#0505AG$H1-
@r2235
TGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAA
+
),;%F52$G2,0EG?..;-D'D#4*H$F=D.5+C*+F9860"$%5@.8510/*%$1/#(;/:$<C!A!=B@#2..><0:+G48<'DE5=+!5E?"?D$77FE+9C-.0'267%!:FH<FH+89;C0A-88(?:+"<?*FC8$:%?")(D:6938"3"10G<@#+089G2:4@+7C.:7,'F;=(23(=.#/,B3+>/D>H>'1).4%B+C9'(7"=8GC2&&1#9!(B$A0A*+FA,1
@r2236
CTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGAT
+
.0)0:<$#-D/3(##*E+#?G*B-"8-,%E;;2.D52:,.#5C0
@r2237
CGCCANNTNTTTNNTNTNCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCNAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCA
+
%*&)'!"(!&%&%!(#!"+"&!!*"!''***%&*#!)))!)%'$#!(''!%#'%)!%!!(%$%+*(#!$'")$%!!')$%($*"$'$%%+*%+'+)+*!"&+&*+#"'*#"))#%!"*'+)$$*#&#%))#)"$!)##*+&!"#"")))%(%'#)*+!%#$!(%'&&*"++++'!%+!%*&(
@r2238
ATAATNATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCNGTCTGATATCCGCAATCTGCTTT
+
E70*<A#@E$#=@5!3:4;#H4$/A9"G=>18)05$;00".9/H?;5F3<"E-@"5C=(*:@0'=@GGA%6?=&<#4>:F6A?(52"$GC;DF473E.8*(==0F5
@r2239
ATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGNGGGCTGAAGCCATCCGGGNACT
+
-=3#%)#H#))*7B(31<8G2F@F@<*14-HC1%0AB.$88G/$2D9#8C.(25/?DH@&&;%:-E=
@r2240
TAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCNTTTTTATTATTCGCATTCACCCTCAAGCGTAT
+
B8"HB;.F-.BC;<,AB<C2"7(-1),+#7,?:>,98=:&A&A#1@0<@>H>/A<,#-7AG"E/?2(6/1H-9'B8C@=+?<G
@r2241
TCGGNGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAANGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCNGTACGGGGAAATGCGCGT
+
%"**%++!&"#'(*&"+("#")(*$'#"!$)'+&+"$)*""!)#)#'#&&%'"&!)!#)"%!$*'$"*")!%##'*%&*"#!%!%$*&#!&*!%))$)($!&(!&%&%!")+%$&!)(*!%!'#"+'($'"('+"%"+)$)#""!$('+""
@r2242
GCCGCCGTGCAGCATGTGCCGGAAAAAGNGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAG
+
&07,<//5$;%/."H'3D>E8G>F#G),@'(,%+6().2H!59(G,;CBED>!F<)#)G&-.+H!C$GA69$CG#?E?0E)'D:5E15'+:CG.1?B-<C$:FH?#<#F95/8')(78;H*%5-%!/?"#4(G1+C*#,:@"3"HCA$6)E%?>$$,1*;)@2$67)+BF<%9(#B72
@r2243
AGAAGTCCAACCCAGATNACGATCATATACATGGTTCTCTCCAGAGGTT
+
6HF=6</$?EGB0/*2%A8(DFH-E;!4DBCE*+39&$70#);,!%6D'
@r2244
GTGCTTACCTACAAAGCCCAGCGCGACGAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGA
+
)!$%$($)+&#&('&*$+*+'+&&#'$#*+&))"%*+%#*#$(&&#%&(*)%!($'$"!#$#+%'"$)!')$&$!$!!(!)"++&!()'#(&'*!!"+(+"***+$)+!)#&)%'#$!)*(
@r2245
GCTGAGGCCAATACCCGCGACNTAATGTTTGCCGTCTTTGGTCGACANCCCACATGGCATTCCACTTATCACTG
+
E+,"!DA?&.H9#'-D*0=11?H$307H,"6),==<F3!BA*9@D,1//D?9'$%A3,CD"3$<D94#9;$A7A
@r2246
NCTGCTGGTGTGGTTTAATGAAGGCNATACCCGTGCCTATAAAATCCGCTTCCCGAACTCNATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGA
+
#-A$E)";D=&A?=68*%$*/5'!"$>')>D3$'2!:G2C:(972?*C02?1A1)1*24C"4D!=)263B9>6F'@3+>/6-E"6514250$D2"&*6:E/08$8FF*?55+.;#5,)313B?$%6GH#,;<2!*'/"8(=-H*A.)@//A,&F$@21E8
@r2247
TAACGGGGCATCGTATTGTAGTTTTCCNTAGTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTGTACCANCGATATAGTCTATTAATNCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCT
+
+#"#'(#%#$($!#&")('%$!"%%(+%#%+$!)())"!+*%'(**$!$'&)*&"+!(&+("!&($#"%+)%$&*+!''!'!!""(")#&+"+#%(#)!)+$&&&&$+*$+%!)&+"))('#!+(""'())*$&%)++!*#+&$#')&#&!)'
@r2248
GTTAACTGGTTTTGCGCTNACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCAT
+
<>#6GC677B$9<"+!!<"$F!!%:";6)(6G/=E):'G#F7#F?-@17B=1(*B/FGB.FF.>F70@&B*-?);'CD9,2@C5?:&&%)*.?F,,!4#"D1
@r2249
GACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACGAATG
+
.&5=-B308469D+<-C@F.(CA1)/?C4*8/,&F)<9C3:'3$G/E@'>5)G,);>0E<<,<9-E)&%#9<E(/@C01*&#1,<8-=
@r2250
GCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGNTCGTTTCTGATGATTTTGCTGCC
+
.#!=4"C*-6<CB*@%".4:;1$C%@E.47,6DH0#;,CDD,":B),*C#<15&*95"7?:77#377=)"E0079)3A:@3H2<@3:
@r2251
ACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACG
+
1:9&5H!*A2D$'AC&G(B'C9?9/$H5>@.34"%3F6!2"6)&8/1
@r2252
GCANTAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTA
+
EB@@="@E2..30C4#(15.E42/77=C#"1DC.'%@4D%
@r2253
GCTNNGNTGGGATCCNNTNTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGNAAAAC
+
*"&###"'*#!"($('#*!+!$#(#!&$"&+)*(&"(#)(%)"*!*)#*!"'*!'!)$
@r2254
CGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGNAAAGAAAC
+
4*:BE@*@19E;.21,3FCAG)68?><(.7?&H#9>1*CE52G(1H1/%9F5$!(AG!A$-</*(-C@;D#5<
@r2255
AAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCT
+
@B?9!:=6#,&FA*.+-E!G55374H5&%:.+#-*1<4AE0@@F=,6'
@r2256
GTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAAC
+
'+&(%%*%++("")+&""*('+*+#!*+$)!(&'!%#"'*$'(&&%")$*$)
@r2257
TATNNNNGGCAAAAGAGACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGG
+
($&&!$"!"'*+(&)$)")"%%&)!(#(#%(%*%!"!!%!##)#+&"*''%$*'$%$'(%))%!*&!%'&&&%
@r2258
TCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCNATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTG
+
=-,-$!.1;:*0+0'A+:'G<&E("77=00H9E)44@78/5G("<98:&2+2.G9:*<0DE&6B,+@57@%+-"5>B<18"?@/5E&)+E?A/?54)?@H$=6=>*B+$65>6)@32':@;-=+=
@r2259
GACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTT
+
@C*@#6C1'97?);!)&4H$=0';/8?3BD$9<0C*8.)2?.#19'("@75'.B'@57<G/CB
@r2260
NGTNNNNNNNTNNAGTNNNGCCCNGANANTCCNNCACCGNNNNNCCNGNGCNGCGATNATAAG
+
#"#$$$$$$!$"!"!##"!$#""$$#""!###"!##!$#$!!!!#$##"#$$###$"$!""""
@r2261
CCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGC
+
H=AD(3E/<EG4B</A6/G7-#F@4,6."HE4C3FC?+04!5/F7>>G=
@r2262
TCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTG
+
#E#5E2!"D"B:&6,?3(;F0=;*'(.#902@,1&1377!?5?F31?25
@r2263
TGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTC
+
E76+5,5;/4G>$:#FH;6)G/*7D$!1(!B6%,&3DG+:;0-$##>:572+%)41;H,C03D?%--##9
@r2264
TAACTATTACTAATGAATTCAGGNCAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTG
+
(E.1"8>=141(>86*-06!)CC#$-,*?@CF(H06,2:?#A;BBC:1F@6>'/5(,@2!#?
@r2265
ACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGC
+
4@==7<4AG/0*=8%7=55G4@(%#H:)23H&;.849@!67@2")F@(&B3A=,@@C9:25B9#5*.-,>D1#7!*8D;*352>74F@,=)
@r2266
ACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTNACCTTCCG
+
>H#F$B%&-)"<?%'%F5F$!-%>)#,B(1-#G>"<G45=,1=*96A!!!F!"0H)70'E&CG6&+EB?(4<F9&C,1!0?/*<4'&"'(D2B<D)$-+@$-#3H"6>3$#
@r2267
GTCTTGGTACGGNGCTGTACTCGATAGCCGCCAGGATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGACGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAANGGCAAGATAACCGNAT
+
!E!="4*=*!%8D5.8?,='&.)%C*+7%:G'@41<#8&-0/#8#**=1%$1F3$H$-,)4':!.1!'580:,F.5B949F15DB*2@$9?912EH0)B.:,D41G!H2!1:(9B.*AF>/1B?+4-)16=E92>865@HF$<,C48-(=5D?2DF<8"&54E,1F9A7!0..,45G)%/
@r2268
ATCAATAATCAACGTAAGGCGTTCCTCGATATGNTGGCGTGGTCGGAGGGAACTGATAACGGACGCCAGAAAACCAGAAATCATGGTTATGACGTCATTGTANGCGGAGAGCTATTTACTGNTTA
+
):0>2?9D?;*@';B::19CH<@%0(*'4E(-0#:HH'>?@5E!21&1F2$80F'0)6)HD7(61FC9B/8.7('6%#7>3='=&@5>'7!'/;*B':645HG@)>F)E!:%("EE;49AG2;)+
@r2269
GTGACGACTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTACAACGCTAACTTTGAGAATTTATGCAAGCA
+
D1-"F3%$??9'D23-A*542A)$76<&C=D57=&B-5.3$?5'1)3<??-9DD4+CB3D""D>!425.7<00)7684;,$%,21CB#4&<EF-.2H&:
@r2270
GGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTANGGTGTGTGCATTTGTAACCTGTCGGATCAC
+
CD$>&H/H1,E",3,H>G=1':@20"%E0+H"4'6(=$%@#GF:7(3EF=8*@"%F+001E#.BH)G.;?<>74!#:$F3@?,4</;44609(-=<1HA'4E-4=DG)<$(;*.H%8>&$,E#38:>C6G
@r2271
TGATAACGCNCTATCTTTTTGCTCAGACTCTAACTCATTGAT
+
??;2$'=2,:+%F=9"4$FG*:C=$$;76E)F?7%,,C9/D#
@r2272
AACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGNTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGC
+
!#+$&+"&+"'#*))##'#"&"##*!($$#+#+#$"&(&'"'("$$!(""&$(&$#$*$&)*%)&$+&$%*(')#*)&&+)'*#+'#)&(((#(&$$%$%#$%+$*(("''%+$%#"&$$)"$!)*##(%!(*()*"$'
@r2273
NCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGNACTTTCCACATGCAGGATTTTGGAACCTCTTGCNGTACTACTGGG
+
;HF2<C&2B"D>0!-29D,)F?!#'/&#C@;"0E$C@#0+$HD/6(34)$6AC/*%$574!/@58/'3<57D1.($&'E.@<1.D6@#=2
@r2274
TTATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACATTT
+
"!0<6DC&#3/4$00H@E/;'>H=60'/F.:7(5;!F3%C+>5&E:F0,E1<F<;/3,ED;2!,?59;CC1<;,#0D-=(?;/-<,A)D%8(7:G:26-%.%+BB6&B-9
@r2275
TGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACAN
+
:H?>@"4/(HH7?'-8?B"6$/):0E!)10>-.4-21AEF4#G:27?":!H&DG11/@';<=%,<+00"%1
@r2276
GCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATG
+
(//6B825#.$9"D%63C7F8:H2&1!:&!*(-)G?:+4$)%--.B9?'!BH,<?"=+629'AB/G-!H7E/H$=,4
@r2277
NAGAATCGGTGATTCTGTCCATTGGTTCATTCCACCCATAGGTTTTACGCAGAATGGCAAGCA
+
!=161'.4$'%C)+6@$/@2-%;E9@#H:+3@D40H!AF'1%H(?=,(>;D.$<B+*.&+5E%
@r2278
GCCCTNGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGCCCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGC
+
D/=8E/65./+,"6E6:*&H,D=BFE%#&<?AG+>51%5-3)F3F@);@,EE937$F"3%G?=.6-42!'5?HAF>'+*'*B<<3!6C'-E6&+,&1!463#3#@-4(&:E%8@.&B34B5&)0?4()1@>437%-B*?@7:7H
@r2279
GAANTGNGTACCAGATCGTCTGCGCGGGCATTGCCACTGGTAAAGTTGGGCAACAGGGCNGCATCC
+
&$)#'%##&*+*#+'"!*#$$%)&)##*$!'(*#'&+!'%%*+)('(++$''%%"(&%))%)')()
@r2280
GCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATANCAGAAGTGAGGC
+
H31.5"2)#(<(@F.C!.!&%+:(4@;<E7:-&70./>7BC!<!E3$@6E<H8G.A&)B=DD@+16"B&!37*+0-83!62"@.('50G5-.>'&>':*F?;7',6"%=32CGE+>+%9+'!%0.1-F%.;3*D=G#)C-HC:!5./>E,56+AE,6'2D4/=#B(3:-#.:H<>-*G0?C@!%19B-+&1$8%?"'.2:.
@r2281
NCCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTNCTG
+
".F0+'9+0:2+1D.;?E.<?A,A3'9227(BF/9"/;&"&"$'"$"-(E""
@r2282
TTATCTGAAAATAGCCCGGCGTCAGCTCAATCNTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGA
+
H$>'2368)*@9',E;G7/@">B$./GA+7<CDAD";+/.BE5&*2;H7GBGA,C&*B.+!@1<+'<!#%A=//4"265B:,A0CH@&&6%))#&2*90=6"/?86,/3%;8?5
@r2283
NGCNNCNGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCNATTACACGCAAGAAAAAACCGCCAT
+
"(&""%(+%'+)#((+$%(")!+!%"(*($$!')#"!!!*&"!$$#%+*&+$&!'')('#$'#+%!*'&)(+'$&%$*(+)
@r2284
CCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAANAGGTANGAGC
+
$E$&2=!HA@=)9#H>0)$=,;,H?-%=+BBDH9<E<0EE6A40$E(H>
@r2285
TCTNGANGGGTGNAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTG
+
!"!%!!!%!+*)*!$'+#$&+"&*)$'''$'!%+"&%%&*#((#+'%!')*"#")"$
@r2286
ANAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATT
+
)%.<,-(>4B'7%HH9BH55;H1A2/:4-%0<A+B$?,5$H*:<0$*A>2+9(A8.470H#0.GGC2$5<'=$B'G7$>CBC'H:@./'0173(%.%,?<G>33$8/@@H#'
@r2287
CCGCCGAATTCTAGCCGCANCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCNGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGGCCCGGCTCATACCGCAACCGCTCCCGGCGGATTTAGTGCGAAAGCGCCTNCAATGACCCCGCTGATGCTGGACCTCCAGCCGTAAGCTGGTTGCGTGGGATGG
+
)?<<)"/B6;D$2*/C#@8,*C8?!-G55!;%$3&EB?"*+;C3-B=(2A>#"G#4F1F9G"B,,7A-9&=0E?"!%&4D.+H>78'7;$/8">3B=5DB81.97/!%B#GH0BF(+7)/-"GH&C3@>>(@)G2!F)$,)'3*>($%+.B.@%H3E=D'$7-;?;,-F1&96>3A/77E<GC+D:B.76-'4E24+!'<F&1C&C=.?9.9//7F%B@+)*G&>+:,<4,,CH!9+=-=G88H6"G?<B4/>6>42(D'=:!$<<'49CG*A0<;E97<-=A+?1!F.'<.<27'#8G,(B(1;'+36%
@r2288
GAAACGNNTNNTCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATNGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCNTCGACGCNTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGCTCANCCAGGAAAGCTTATTACAT
+
&#$")'!$()!#+!$%#')&(())$#+$*##%)$+*$)#+$+*!('$!(%#*+()(("$*%&)+&"%(++!!)&$*(''*'%*&)+(!!)("''*''*+'$%%*(&"$$#$$%*"!')')"$+$!*&&($*#%'##&%($+($'(*!'*)))&(*("%%(&%)"*'(!&++))!++"$''"*!&+#*$++*)'%%)!%%%)#$#%#'*)(!$&+)#'''(&($+'%"!$%!&)##+#*&$!!)"(!%#)*$%*!(*(+)(+&++&&*!$*)+*$&"')'
@r2289
AGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCNNACCGCTTTCCCCCGCCTTAACCNGCGCGCNGAGTGACTCGCTGGTCTNGTT
+
)(*)+"(+(***+'*$*!*'!"*#)!+%*%$'&$$&!*%##%*(*##%()&!'))''!%###%#'%&((!($)#&%(!'(&$$*$)&+*"#++#(#)
@r2290
CATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTTGCC
+
B)#=>0;?#/$"H4C.8@#H(5=6E$.%%#B3*3+*7B(3A73<71#21G-9G=G>(3*#$#4<(3
@r2291
ATNNTNCGNTCNCNANNNNANNNGGNCCNNTGCCACNGTNNTCACNCNNNGCNTNCTNNTCATCCNNANNNNCAGCNGANTGCNTCATNTNGTACGAANNGNNNNCAC
+
!$!!#"$#!##!$!"!"!"!!"$#$"#$""!##$$!!!$"!$$#"$"!"!#$#$"!$!!!#$"#$!!!!#$!"$$!"!"!#!$!#!!$!#!#$"##!"#!$"!!!#$#
@r2292
GCTCGCCGACTCCTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAATTCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTNCGATGGTTGGAGTTCCAGACGAT
+
176F8*2DC31%@H0F**=3&)>67GH.(!?$@E;-+@&$><*//BCF(1!AD(<0G66D).,*@88G*6+>EG$:#55?'E68F/$1;=EAD#1+C;9#BH1A%FC>81B<,/,$#+?4-,H5D7&%B=A@*(F41<?&E,:B>(38E5!;B</*68A;<
@r2293
ATGCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTANCATCAGCTAACTCCTTCGTGTATTTTGCATCGATCNCAGCAACATCACGCTGACGCATCTGCATGT
+
FD;)0#<D+*<3$6(>C,,*8*:0-#A;!(@%$A&CD3)0EA@=45/64!(,"81;7%,/(;')7>9F!C2,-#?D?B"A-#/=':$4(:'G?<C52?F<++BA@/<@@H"E+413?;!/!1C$C<52CF:+*!#!D%.(A&!G7A%B)F)81+5)!7A6-<"4?":9;5GB(-9!C688(C,'1(>58";&CC)#5(@D/!4E+B/5!>?)?BE&13($@
@r2294
GAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGC
+
-*"9/#&!*<1!*.9%(BE<&'F<ACA"97C?+)"#%=%E&?A=5-HH8>6%4)/74#15E/<#%##?G'@)%49;.3!$1?99;@C1:/C,<$)8
@r2295
ATCCCCTGTTGGTTGGGGTAAGCGCAAANCCAGTTAACCGCCCT
+
=-&3B>2F<B)->=0--;(19$4F#<G:8$*/"AFG-8D;:#"#
@r2296
CNCGGCGGGTAACTCACGGGGTATCCNTGTCCATTTCTGCGGCATCCA
+
5==7)=+.06G+:9"B=C+AA1@D.&-39949;/5/D-H2(."'G,;5
@r2297
TGNTCANGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCC
+
('#)*"$%+("()&+"%')(!$+#"#'&*'&)!$'%$'&!()#)%")&(()(#*("'*'%#"!$%'$"%%#&*%$#+"(%#+($+%*'")')"'+)$&()*$#%!#!'(**%!(&
@r2298
NTGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGNAATCAATGATGTANTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCG
+
'*<<.49+(!4HC#7%F&&.':&>&8%15#"276CB()@7G-@;,>&:<;&E*6</7%1:1"543GAAE%=9G!;$1H)*B/@$G8)71*!GA38.%+@-6=-9-,)7C-:"<:7+A>80'+D#E7"+=*-$A2%E-@29*%F&2@3=BG&'.!;/,%C=4(/2)3%*/@908@3)F?C!%63F?!7<D<
@r2299
GAAGTAGCACGCAGACTGNAATGTAGTCGCGGTACGGTCAGANAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAA
+
;/"0>F$+E37HB(,1.E;6E-)<<"0>=23&$',8B=7&?$6#%:2<;#:->>65@D$/'54<>&&/<9=D7GGD-#6B&6=7#4
@r2300
NCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGC
+
&3+<(55/FB2):6C2(50G.@;"43,B-''B45B!:,.5<+B"--#9B7H::7"<5<&F<2!+94=%+#D1&8?G/*A-6E#(;:<*F*E$6$E.13F./#A
@r2301
GAGCAGAAAAANACCTGGGGGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTAGGCCGGCTGGAGTGAGTGGGAAGAGAGCGC
+
+*%%)*#%$!%&(%#)%"+"**%()'(")&+!!!%!$#')(!++"#*!)'&!'%++%*#!#!#"$"$+&+$!+'"($&*''&&('#*$%$
@r2302
TACGNGNATNNGNTTTCNGACGTTGACTGGNCGCGTCTGGC
+
*$*(*%"##%"+$)%"#&#$*+&%'&"')*&(+'!#""$')
@r2303
CATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGG
+
ED"!05-!</>+2G8.4C8-.B)7.;2@!96#.30+-&H9921%B8
@r2304
TTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAAT
+
/>5-E.#%AF'?-"#!H%G?@?4A&0+.18G104<G=E%<5=2832#/>11*CH&:<3B2)!F&?/4C;?H&B'9*:,7+$B28.5<@'//=51/H'896#C@D<G6+5E!?,8;H,!20B%:
@r2305
CAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACNCCGCTGATGCTGGACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCAT
+
>CC*,1&!7,:6%%@BAC/@:9>+A!AH-96!*%E,HFE&EE!B1E52!726;.)H#'0927'5$-H9:E)C(-C/4!+?.3!F-G6%@@GA"2=11''9.$C?EE*,<&:=DFDH3C$7:$!%8#)&=?467?)11=%=C'BE"!5@+"0""B<B7;69:*:G;)0=(@"'D85@D#4&5@7DF0=GDG,@@GH:6B?+9'?<7:#$,7%<>.BE:DA:<7H"0B)/B.D!6*H!HF5C7'1<7>*1)='%#>*"&(1.&9=/(:1/&57:%.%%CE!!!#96%'/,::725?
@r2306
GTCACGTAATTTACGGGTGATTCGTTCAGGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGA
+
;0;AD:<7:HAH3'=A&5@%@$C&!H-"84<*C?E8-&5=:/,;84F+("B)"C,G./>,54D)
@r2307
NTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTNCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAA
+
!C4":2+GDG6//EF)H(00:"54%B*9AC9/&5!C-<+)B.8.-'B?3*B-!>,32:B-1<!4?+,C'C9B$$F2*-A'GF,9%B#+1,$@@BFB>61>EC8#<<>8G7"C$1.@GH=9>,+1'946$)'B20#&/4&E;.?%&6B#HH:5G1!#%$41B'"11'/3":9:/1F)B90;C&3+(G(3@4%!0=H*C=$"&'2:))5F:+@*5(5%E>
@r2308
CGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTAC
+
H#9#@5!-$>2GF=,H)>"D6!9-F&-&8D,@D?3*0>(38'=$'>C2F7A*4/B,<@?5E!EDH+9!((,98>=/.#F5HA**DHF??2//&2A!FH",FEE$0:(F03<,$#>58";B8($"FE'.,1F99G%&+D,/0HG*9(/3*7
@r2309
CACCATTCCCACCCTTCTGGGGCCGGACGGCNTGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCNGCGGATTTGGAGGGCAGTTGCGGTCGTGGAAC
+
7/@(*-&C=)A@1%='-H<;92*@G*A/%=C"B)&%*3&3G(!$5E)68<>"<3=2@(BFB*).1B)"0??78A--?'7#A?5:+(!@$,6";D7(BF(%=37(7.
@r2310
ACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCT
+
3)F;:<"@E!39,::1'::*C3:C-G;$HB4$)DF82/?976%C
@r2311
TGTTGCCATCCATGGCAATCATGCTGCTAACGTGTGACCGCA
+
+##%+#($*'#*%!#!(#*'$'*+('((*))))!))&'#$%#
@r2312
ACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCNCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCNCTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACG
+
EBD@H+D5/&.25+F3DG$3->)!>?4A*!;1*@7@?D%!':)6*,">(-1<'9$B9)$(GBF=20!%=!$2);!AEG+4:!B=C$80"E4E&59(B/7$8/74D55BEF'#>&841,3>.H>8@3H2//(?@B+;H:,H-)GCA/%%!#GA<-"B4=E>-27B)/:&(#-1$'F)#>0G$A0F4E,2;6H-%94E'BH>D3>10&<,:8)#
@r2313
TNNAATCAANNCTGTCGCACTCCAGNGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCA
+
#!#&&))(*!!$&'(&++"(!*#"*!)*'"%+&)'*$!!)()))!!!(%+)*!'!%)"%+$(#$&!+(!"&%$')""%$$%('&&%%)$"*
@r2314
CGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGTTGACATTTCAGAAAGCGTGACGG
+
#+#)('+#'#(*)'$')%$!'+())($")%%)*$)#*((+*&%*#*'%*($()%!$&()#'&$($"($+)!&+&++%&+#!&'($'&++&*$"+'%*(%+)!&(
@r2315
ATTGCATTCTGGCCAGACCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTG
+
4+*(B%!2A.??,)$D'E$/''<<G!>$C'.5*2);DF0C8#E2:8.=,A3)AFAC'>E4H)6B"9*9/&A,3&5G:?(3:5-E,6C5!'D@'?>0EBA.,)-4##+"DED/!1,=55D+889C>-C*#*
@r2316
GGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAA
+
+!#%&!(+&($"''*+'!'&)"+!%#)$('&&*)&*(&'*)%*(#&*$)))'*!&!"*)!$!*")
@r2317
CTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATG
+
7213<";&G%*,@+"C7#22,@;9A!<D$CG,(57+4C5G#HE439<4G4
@r2318
TCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCNGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCC
+
GD55(-,5?H5934;>D(41)D)1$;-&!:$.10=;(2)EB@.83;:(?/07&.?:3<&;G%%-*&B/@"HH,"D59H847A+7%(%73<-#817?BB5.A>@C!'C1)4%GB9!F'&=#9+41<(18*>"F5>:#5+,HB6#.+GF6/:8.7A<H=%!D-50$>,
@r2319
CCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGG
+
D4%#2066$A.H.FE03#C<G+'74;#<B&$=<%+/>.*!>:FH,(;.+
@r2320
TAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTGTAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGNCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCNTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCAT
+
2F-B?E>0;A77@5"C=6;4/:&@@*:CG7,8:?(/@#<!H<?#(-"D*4'G9@:7.?8-38%A2'<AE0;G@-105#/0/%=1,.(H4E"+04<4&%$!B&,A))=@-E!(A<G'2C6,57A*@+)D*&1;+;D'$5E@0$+;+>)>$E!<,F07EE6;6FBA)A72/8'G2::#7@12!G!E9?7$&'C!%$GD
@r2321
TGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGAGGNGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGNCAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAG
+
:-)4*G%H8@2$>%9$=@>1,$#(8D7':<"05'=$F2,/'<CB>G2%!6>,/!21)DH?+9*/>.)*":F*EC&%)$#*=2*AE(<HDBEAGG7B8!<1>.B:CD#89&>$*8<G#0!H74
@r2322
NNGTNGNNANNTNGCNANACCNTNTNGNNNTAGNNCCANGANTNGGNNNANNCCNNNANNAANNGTCACGNNGTANANNTNNNNTNNNNTN
+
#!#!#$!#"!$$!#""$""$#$$#!"""$!$$$"$$###$$!!!$#!"!!!"$$"!!$#$!"!"$#$!"$!#!""#"!!!#!"!$#"$"!!
@r2323
AACGCAATATTCACAAGCAATGCGTGGTGNGAAACCAGCACAAAAGCGGAAATCTCGTTCCGTATNGCGTGGAACTGATT
+
+&(D.>&,"%##G1.9H(-$*8(/A(G0+855=))-EC4782EB</01H3;,29'*2-0/8C$B=22;.-4D*.+!G?,1
@r2324
CGGTGATCCGACAGGGTACAAATGCATACACCATAGGTGTGNTTTAATTTGATGCCCTTTTTCAGGGCTGGAANGTGTAAGAG
+
%:,?8H<D8A;?%A73=HG$1DH'*?<(4G26,G$611*&9.E9""!4A/2;B'FD,=&HG8"F!H;:6:+2GDC-2'AA-;0
@r2325
CCGGAGTGACTGTCACCGCCAGTGCGGCAAAGACNGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTT
+
!(")))!+"()($%&#*%$'&*&&*)"%+!!$$)++!+#!"$!$$+'')*%')*+"&("!##"'"*%*#&$$*%#'(#
@r2326
TCTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTNGATAACAGGAGTCTTCCCAGGATGGCGAACACCAAGAAACTGGTTTCC
+
#25E+<5A/%=&2+8?2/(EH8#>>*87/$&4'-%<#&+"%6<!3&(--H$$,@H@@..;>GB)(%A/,%4@$F02D9:*>FA</4'#
@r2327
TGTTATCTCGGATGGGATTAAGCGTATTGCTAAACTGGAAAGCCACGAAGTCCGTGAAGACGGAAACCAGTT
+
,$!8+)8,#6"3$=%+A>A<=1.C28*=$"2D;5'+G%6>>H'A$"0827H>>60(E/H"G@-4C/,&<E>(
@r2328
TGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATNTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAANGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAA
+
-?97-8'<*;>3*#E26@4)0H9(@;*4E8C6*>>+0/$>H+5%@;B?F+C9&36-?EFE0?5<0/A(16E@=/>EF8*#7)E*7%C!@9!E"7E73"8@&$AA%</"F3C+7@>&,++HH&-(G,A0=5#$9<@#7*D3E=:B<'>H#+,/F,B4">2H(/*;83H$5@:G>A5"6#,HA.A=A+@8%"%23F#=):562461G:8-%=';"2&"-,H?D/)'9%(2/$="";;&9C*DFD:1H1D,*<>8<-3"3,=,C
@r2329
AGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCAC
+
1D3BE+H1.&'1@!$+@<0G72#/!=H05899)$'6;B221C6CA85HE6<2)/=C$')37AG'3(@&37FD$%%2<
@r2330
GGAAAACTTCGATATGCATCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCNGCAAATCCGCCTCATCAAA
+
D2B#-,4DD+B@?/?3B:/3$?-%=<$G+!?,&HCC>,*C%?#2E9E1=+H.0<:F":?5B*D!E27)HC%9B41(1G7D,--.8!&HBE2:F*8@;$3AB.')/(+5!7)#
@r2331
CCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCAT
+
D#26H-CG?1"F'E2/8$7%!:#6&2CD'D9CDD"E!"3+75$?;/"B30@>9%<%9,@:&&5D)
@r2332
TNTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGAGTCAAATCCCTCCGGCGGAGNCTTCTCNTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAG
+
%#+&+"('+*&'(+"%")"**(%($""%+#***#'("'+##!&+()'**&$+"*+"&&'&"%")!!"*!+#(*%()%%+%!!'"(&'&(#&+")+##!("!$!!'%"$*($#!"")!%#%*%)$(##*("&"&#$)())*$'#"$+"&""%
@r2333
CNTNNTTCCAAACCCNNTCAANCCNATTGTAGTAACCATTCGG
+
")&!")'!'($$$")#"!*'#%'$!'('+*#&$*%$""*$+%)
@r2334
TTNGCGGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAANCACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAANT
+
&%##'#*(+%''#%(&+*'")&*+!"#'#(+()*&(!$&*+("$*)%!#+%"$**++#"!%%*#$'+#(&%%#&*)%)!!(*(((&'$'(%%!')*!*"#)'*$)+&(+#!#%!$*%"'*(&"%)(%++%'!)!*%!)'(('(!%%'(!+&#+$%&%)((%+(*)'&*)("#+!&*&
@r2335
CNTCATTGCNCCNNTNGACAGGTAACTTTGTAATCGCGCTAAGTTGAGAATCGGTGATTCT
+
##("&%$((##%!###&('(+((%+$"$!&#%"!*'#&+%%(!"$*&*)"!%(*$&!+('"
@r2336
NGCCACCAGTGCCGGTTCGGCGAAAACGTCAGAAACGAATGCGGCAGCGTCACAACAATCA
+
"(2<C?=>#"'9!)AEG;'/?E/293#AHGA,G&2FEE'A6>5,@-.=#G7#F6%4:-G=4
@r2337
CGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCC
+
/.2*4441C#98=2#>0!B4*3A:$:"9:4+"A-$:;((C4B)6<9$C.5(@)$1E.!)@'HG42<
@r2338
ACGTTCAGCCAGCTTCCCAGCNANCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAAT
+
5<E0#C076$2'-5%>A>'1<E07H7,5)F2>H9C").->);D00<CA"9(%$H,9:9.<!*FB
@r2339
TCNCGNNTAACNGCTNCCTCGTCGAACAGNGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTNGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGNTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGGGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGG
+
**&'')!&%!*$$"%'&($'#%#)!+'(+&*$$"!'"+*'+)#$(!)#%'$*($!*&%("%#+($%(+%%+%))')&"*"')&)++"*"#+&&#*)%#&)#(!+"()(%$#&$*$+'(&)*(!+%)*+%%+$")**)&)*+!'+&("*'+'%+'&$*'+*'*#()$*'+)'(*+)%%#&(#++*!")#&*(#(++%&+&$$&!&%&"+!#%*)*%$!)!%')*$$"%!'*$!%$#)*")+%*(*'*!#%*'#+)*
@r2340
AAAGTTTTGTTCAACACACCAAGCTCAATCAACTCNCTAATGTATGGGAATTGTTTTGATG
+
B!9G=!=@<H)3:/72<)B(06360'/,AG885&&E)74;54=-=@D'.H.071!BB//.3
@r2341
CACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGNTGAAGGGAACGAGTTNTNATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCNAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACT
+
7(H*7F;59+>3,76$92HB"0!GAAC.!13CG?%1G1((,98-;8"-6;'$'(,&)!1?&:4;+2H.$77&?0?*:7C-D:+G.)4A=.%(6/H$D1'B88?6!7,9GD5#GE"C?@@?A+A+:;(50;2$533E=A>)>4%25F;E->%5H!,.7>"(:A<&F6E)G13D3A!)3;2AB14<*/+(0D42?%39H9"-=>1&=.C.!+:E%9.1254F2%>0E<*F$0>5(BA>HG!:);H2/$<:)G
@r2342
TCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTG
+
-?$D;9#@D8(77?1/H7#=C1:,/18GE+8F+#(#3;623*EH.+
@r2343
CCCCNGCCAGGTGACCGGCTCACCTTTTTCGNTCTGCTNATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCANGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGGGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCG
+
'''*!+&"!&$)+%&%&)*%%%+*#&"***"*()&"#&&$')$!#'+$(#!*!*$))$'**&((**)'((!%%+(&"###&*")'#(*+&%*$(*#$)!$&)!#"!+"$%)''$+'!"&'"")(&")")%(*''%')$&'#($&&%(%$(!#"$)*"'$))*!*'!$*&+&"'&+(#$&$'"$$#()$'#%%+(!+"''"*#($"""&$#%"'++(!#*'%%*&&+%##*((!#+!%))+"*!('+)&%*"
@r2344
GTGTCGGTTATNCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATNAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGAT
+
79+(4#*1<37&'3>F$24*#-F?)B9%;DG0H533*.*@484AG,G)7/H0BH92;+=B4:A4,"+GD:,7=04->!-GCH.@6,4D<+>9<3-
@r2345
CAGACTATCANGTCGCNCAATCTANNGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTATTCGCAGATATNACGGGCATCAGTAAAGTCCAGCTCCTGNTGGCGGATGNCGCAGGCATTATGCTCG
+
)'#&(()*(($%(#*(##)&#$&($!+"%$"$""#())#+&##&"""&)("&&*"%!%"%(*#($!+$'#('!$+$(''%'(*+&#""#$"%""""#+*)"#'&'!("%#*&+"""!%*"%$'(('$+"!#!"(&)'$)$*(++$
@r2346
GTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTNGCNGAGATGGGATTCGGTTATCT
+
B"(#B"&;$CG%B0>/DA*C;7<+<)@4;-$E565<74G>F:D?G.36,426*>*(0(;@+D!0E1*H9/7H
@r2347
TCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTC
+
CH@H.+.G0B<@2/)-2D6#D0BD'/5"<4-&!D*"C="3D@*BGD0"
@r2348
TAGCACGCAGACTGAAATGTAGTNGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAANGACGT
+
A:1=?."071><F5%4;,$'168-A.G'/??G?-5),@4%%3#=A77C*2=GE(E/,*!H8.:83C"&"AC=B0=5"HG)A3;F2G5+
@r2349
GAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGC
+
.$1&(;G!##=<2C@1$0/4>=A!89-E*#5.EAH5(74:263CG
@r2350
CNTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGANCTAAATTAATAGG
+
/@2=3D>+-2>4;=3DC884/G0C$2"68CC,*.@;%=?2B@42A"((4!&:D)/
@r2351
CGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCANCATCCGGCGAAACGCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGNGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCA
+
5D3$(@7?A31F+!3)CH<-!?'//H&97+>E>+4F?%-,;F5G9CBD5/!01%1C"95H&H&G<;8D7$)>89?';HE94;*(/=8@B!9*2&'220%/+G/G?"=06%-G!E?5F*997G='))9*+1CH1DC))=99#7.7E=*9:1@=,BH,";'+*D8;<13G9&,'?8%3F-B&.=$5H"1;
@r2352
ANCANTCCGNNATGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGN
+
)'#$!&&*"!"+$%)$#%*$*)%!*"+)%%($&++)$")"!++#!'$*%!#"!(")!)++*+*'%&'##%)"*$(#*
@r2353
TCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTTAGCCAGGGCAGACCACCGGGGTGGCTGTG
+
)?>+>BH%)2(&9BG/D0CG'C$+&;A<E;DA7-<4F0/6=';5E&B(58DE+A,:&H*2+%=0C&5')E'%)5>CG:1A*;1<@*<$7AE
@r2354
ATATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGC
+
#+&!%)&!&%$#&##**+&%+"+)$%'#))!"!++%(*)$$)+#"!!$''
@r2355
GGTGCNCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTG
+
85@<@F#)!3;#/61?<#0)-F+9?%63;),DF!>8(+%%?=HB/F4,:@2;8.
@r2356
CNCGCNNNCGANAACTTTNCCGGCTAGCCTGGCTAACCGTGACC
+
'!#%#!!##(!%()"(('&)*$")"((+)$"()+'*#$'$'!&)
@r2357
CTGTNCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTG
+
0>A&'2,%5460':"6>:;)!D8A:*=;A"8?08#D#"C0C)*'>&!9(0C4@-/85=",&5G5*B'72@%?G-F)&+
@r2358
CCGCNNNTTNCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTC
+
%''(!"#$&$+*#)*#$'(*(*%#*!+)+(!$!#*)%'(')&(#%"#&&)*
@r2359
CTACTCCGTTNCAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCG
+
E,%&(F8(,4/C(-?E-,F/4$FB)0,)=#D:0;9!"?=='/77-7$5*H@6CA3=)C;5G29;'(323D+(H$?9674@5?>68('7-%G>C7HG7*1)>)CA+.)$42>3!88?8#'D%0*;H?*##?D$/!B@3;/=B'+*!#,.%3EG;;G:.F3
@r2360
AATTGGTTTTGTATTTGGCGAGCTATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTT
+
9276?%"7(5<+:=(?8,E;:,,9B31>608"&DD"1&/H7;>*3HE$A+54G$B56/()7$-*2;C>36H.'F#%='ED1@<BH#C1;D4(1+24!5H%)A:=48-#A"C;+)",.*=0B$>
@r2361
AACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTA
+
"A:5BC7);'48H+%A-;)#D&G&6D&$H"47543@*-1!".D2,%.%;>-,=<4B=*GH;'
@r2362
AACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCNCCTATGGCTGCATTCAGGATGC
+
E=3-B%8G4&,4<.&E;$*<6??+#@:H&D%.,D/*02::45%@A!@7B"@BA8<9-C(.3($BCC?72,5?.6E,#B9+
@r2363
TCACGCCCTTCACCACCTTCGGTGNGTCCCATCGAGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACG
+
G.#E:<?B;'.EA,;-,:*-1FD56)4HGC=*G*,EF#:..?'$5E(!.("9++@:5#A0DG("7BCG/B4
@r2364
ATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGNAAGGAGCTGCTGGAAAAA
+
B>&9.+(6+9>=21A08CCG'E;DG5=!D33<4&,57@E@(D%+7'B*>9"?;8E"
@r2365
TNNNGCTTCCGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCATATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGANGAGACGCTGG
+
$($$+&("'!(*###'!+"'!#+"$("&#($*#)+#!"(%+'*#*"""&**%!!(!'#*)#)%""$($!+)&"%)*&%('!$&#'+*++)++#%%*#)!!"*'+)&!()()+#'$($$'!*'%!*(*%))+"!(+"$((&*++)(*!&*($#$&#&$(+#"!(+'#)'##'%!%!'#+&"++&
@r2366
NGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGANTGAGTACCTACGAGANAGAGTG
+
%5=F-&5'4?(-6B<@9548F>#C@,.G(!*14C3(,3+F++A55*(3/*CD$"?3!
@r2367
NATCTGTCGCAGACAANATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGC
+
*H$!10$+D'E'$E:7><E/;/-1@4*4EC'6E12'88-&BD1A?1+3A.9:DHEE*".
@r2368
CTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGT
+
.G34*D"71$!4?+:G.4&"<290E?.@%7.=21H;B"2C!
@r2369
TGATTAAGACACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTA
+
A/:FG/H'9C7#./<('G-#=4(?/-188!:%B>B03#C.7*#*2(
@r2370
CGTGAGGATGCGTCGCCGCCATTGCTCGCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTNATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACG
+
+'$'%!"'&*"$"##%$*#&(&'&($""!#*!(++!+($$$+#"$&$#%(+!$'!(#)%*&(("+)))!#)##$&#%!)&**+"!&+#)&!"*&)+&%')'#"!)!"$%++#%*")'*'*(*&(+*"%"(%!(+$(%$#)!+$(%'&&&)#''%&!*"$%%&
@r2371
NGCNNTCTCGCGGCAAAGGAACAAGNCATCGGNGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAA
+
"'*"+$))'!''&&(+%$#+!)#+(!"$(&%*")$#&(#%(""')!$($"'$%$!+!%%$$&*!"$'((&$&('!*#*"$!)%$#&$')+#"($#*'
@r2372
GATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCCCTGGGCATGNCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTNCGGGGTG
+
G1;?-C9--1(;G=(H>*(C6:B/GAC'/:$(H5H(*.53H&:*6E0,D'%$-#6((=7BF$9$H,-,C)'C*1'6'3H8979H!.9,0-F"!@)2C:5!$F,4E<H,<%D>&A)4!4E5*C(2.,=E@0D;;#)=9:@.7'>8B7'.!F);%@73D0*>-F<7F).4";.96G%==<8,#.7<$DC6./57#'@B+"7;E385+G?$)5HF/'
@r2373
AGNAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCNTATTTAGAAATGAGGCTGATGAG
+
:8(2<(,D$>A.=3686G&'C?<H@%"'55->.'GB)'!-E&G*/98A002E$/H#?C+AE><3FF(5%?7H.EF"%;3C'!6?$B:<G?E;:%78>@!@AD35=:2E=/-;B#F8DECF;H%-57+G'?+0B%B?-869.$&&DG6H:#HB>:>&43;#/C$/EC9<&-;1-H67B';6*BA?"CA3?!>9<"/-),@B#E10;/5.)=E;3H!@/EE(23EC%2E626,">67C"+%-
@r2374
CNTCCACTNGANANCANCANCNCAAAAGAAATTGCGGCAATGCTCAANGGNTACATAGACGAGAGCAAGGCGGCGTC
+
"!*()#)#'(*""&*'&&(#'"+&)&#"('"'#'')()##()('(#**!#$!!)*)'+%$&&(!%&#!&)#''*($$
@r2375
NNTANTNANCNNCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCNAGGTCTCCAGCGTGCCCATGTTCACTTNCAGGCGGCGGGNCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAANNCCCCGGCTTCATCGCCGGANCGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCANCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACTCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCG
+
"&&)!("%!)%)+&!&%+*$#"%&'*)!"%#!))'!+')"%*%!+)'%'!'#$)++#'%(()(&%(%'"!**$()#''&*!''($))+&""&+"'($!%)&"*+%&(++('(!#'*#&&#'!*'!+'($(&!$#!%"%&#('!#!"'(")*"&)*(#+'+!'$)&!+"%#+#*")+!('&&)$+'+"+&)(+&(&)&$$$!(!!&%'%*&&((#'(&$"#&!+%(#$#$#))&#**#*&'&#*)&)!$+!(*"#+'!"##))+#''"+%()!&*$%#+(!!*+$'&"#$&%$+(%$%+$(($&'(#$#!&+")$'+!%(&!#$#++&#+"*'%%$(()$!%$&&"&&%&#'(#)+(+#'&!&"+!'%!!*"$$$)+')!!))+')*)'++"$+$'+'+*%!'"*$+!$&'#'+"'%&%)"%&
@r2376
CTCGNTAACTGNATNNACNGNNTTNAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATNA
+
)$*$!#*!$&&#**%#!&$'#"(&"+%!*"'!&%()&"'+!'*(#("%$+$&+&)#"'+*#*'*"%""("""!"(+!))"'*+)(%'()"$%
@r2377
CGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCG
+
8!18.:5:1FF.=0!F#=;/!H5=A*9(-";<19(5-BF&A4>A
@r2378
CNNCAGATGATAATTACGGCTCACCTGCNGGCTTGCTCCGAGTCCACCTGCACGCCGATCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGNTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCA
+
)&!+#''&(")%'+(+&$+*##)"'$)#(!*!"$!&''')#&!!'"#'%*)*!%#"&!&+)!$$&#&(!%&)")''%)&'*)+*%!)*&)$%+!"!&"'+&*($("'#$!(')(&#)'&%!%%&*%+%"#+)()$%"%&*"))!"&'*!()"(**($'*(#!!+"$)"#)(("($'(+#(#+$)#$'&!**)")$'%'$&!#(*%)+&*')"""&%+*()
@r2379
GCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACG
+
,"HD<957E<=/,DD-.#7@FC5'B:%0=34&8$>,!>1@;D9*
@r2380
AAAGNAGNAAGAGTANGACGAGCAAAGAGGCAATTATTCATTACCTGGGNACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCTGC
+
$)&$%*&&*(*")('+#*!$!&+(*)(""(+*)**$+*+$+#)$'&+*'&%+&''#()"'+*)*!'")))!(+%'%'!+%")*+$)!(#&"#*&&""%'")'#!!'"$+#*&##'!*+'###*'
@r2381
CAGANACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGNACGTCAGCACGTCCGGGTTAACGGCG
+
0">;G=0':&GE/69!5$6&5@D(82"@>3=>,)7,';-5?7$/784'H?=23H'%?>BD;F+$BD/18'!>
@r2382
TTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAAC
+
C&2@C)+#<,"9>A01&/.4)&2#=-4+%%0560%9E*04!3B-*A1*>(,D+D80//D&/?F01#5302B7<7=GG!:7$,/;,F1%(&2C@H!0/+0B!.!6F9@<<=F,;#@
@r2383
ATATAGATCATTTTCCTCCTATTGCACNTTATCCTGAATTTTCGGTGATGCCTATTAAT
+
C0H.FB$=&-<6;,=E5$H-<)2+).E.DC$=;,@$8%+%8@8%*EB;(08=4&?(8)6
@r2384
NNNTGGTTCATTACGTCTTAACTCTTCATATNTAGNAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCNCTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGNGATTTTAAACTATNGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGAT
+
(!#22)H+#<4CG3%9@:*+8/,,-A%3E*4%6;(*5H9$"2;C*8&C+/*%44F$7=*51E57.9*-:$&*:E+B83#>B7F:<G4&5,+33'#G88)&8C+D#)@;1.0D1A.3:%6@AH:CA.H<7,0F$582G76?72@,#."A',$2*4,2&!$@!H*0$32'0G<@/7+")A3*7*>8=*>A&CD82A*;>C@(B-0#8@A-H>$@60#)86(701<&C.:0,:FGE,'=2(C/5G&)/60GD#/B?8&=4($!>G5E/@&>53(11B&
@r2385
GCAGCAGACTCAACAGGACAAAAATGCGCANCAGCAGAGCGATACCGAAGCGTCACGTCTGAAATATA
+
G2E)H6#>E4/A*'FE5<HB(4A3)?F,$+9@#H-0C!&-'@6(1-*H.B')CA3.2H<>%%6H3/D?
@r2386
TGAAGAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCA
+
./#@D)1;.&*3D0$C6489$F$5+<EC/&E&0>=<E,%8.H7GD">(E0&/<>,=,8#@,F0/%''HH$+C@7?@$=0<?=5093&HG#83578$)"7&)8?$'D#>>-*F*&31!0/;!!?;5H016*8$4=H&/#=9/A,D%5G;?@HEG)>.&"";G)5FG>7!>$,"4.4:8300('*=*==A?69@6,=&5:1,,%EE$*:784=;(<:C%EA9B/34;9<1)8)/7.D@>
@r2387
ATTGATGTGGTGANAATCCCGATGGCGGTGCCGCTGACNACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACNTCTTCCGAAAGAGCTGGGCTATGNGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCG
+
+0/"12/9;-B=,DGE)';G-=,;.,,A9=?A)1#(:E.8>G)E<7AG*4*&6?),:!F>;A*;07'D>@?BAGC$E<#18<D-,,$$!1/*=81(3:+<C-'1'0A:<832$,<<4,$75A3)4+(DF@00:"%,44*@0@)A0B?(H$&E)C;$6
@r2388
GGCGGTACGCATACTNTCGTCGCGATAGATGATCGGAGATTCAGTAACATTCACGCCGGAAGTGAATTCAAAC
+
E<*D=H<9(86=!30(=4%*;!#:AB$@D'7!%!':;C2%-;#=9">;@/*E$*/$1F;+*:???+H$8D"<)
@r2389
ANTACCCAANGATCCCATGGAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAG
+
+4%G/=2>#;&=;/7;1D0.!)/@(-2&>9",=:#%<*6/C6!A2/@!@1-'FE7*!$;-"C6<G:>';/E)>!
@r2390
TTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACANTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTTCCTGGTACCAAACCGGTAATACACCGTTCGCCAGATCTTACCTTCGATAA
+
0),E'C-"8+2>:E<"#0&%G676.9FGDF<58"+!$!2@((6)4>(*,E:G4-D35*-E1D"C4!'464G%C:/%9467(--4:4=0AAEC3F1??=72AADH,67%0@G/(F'BEEG&4C%%:?,+F+32$8!+'/&E>56)-E3
@r2391
TCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACAC
+
;B:%2/<,@G;867*D.878=F.7G/;,>8)3GF'26"&09
@r2392
AGTGGTCGTCTCTTTCATATACCCGGGAGTGATTACCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCTGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTNAA
+
;7B;>,B8;H-5/BD1:/=/@B898)7?,*8D#2==3:#%7GE#/"G-(D8@)55+$F23!$->G7!6;-1GD4%$7E*##6-(;54)@93:&3F59D-:7FC60>4"5'.5#55E32$E59+7G>*
@r2393
CTGAAACAGAAGGCCGCNGAGCAGAAGGTGGCAGCATGACACCGG
+
,DC4<BF?:#*D?2=.E!0B=$,0$C95).$&+4-E&7@.6@F7A
@r2394
TTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCNAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCCCCGCTGTCATTAATCAGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCGGATGCGCTTCGGGCTGACCATNCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTC
+
?;/=)A+G;%6F?<-7"+7$"8$=.6&5#*<;#4&-0!122(1#:>#2=(@-%%2<;B<!)H1C0?E6,*"EE>*66-).>20:69'6%>)85'1;=D:E!"55@D-!93C8),776?+637.6C,%2>),:0&DF3@E(8/;3=!2&FB+1H0$H!)5&59$@0+?;5.2#A%>,!$'("H=.<&"%6F&%?B:>:DAB4%)%5,!*:D?'+9,G*+(F80/-8--91214;;!<C0/H(@8!.65"'F!+&(@)@C4;C4CA%C)@G$?#62H8#,++67$)*@HB9;!A=/;7><<8H%.=6@+"5'35A'!&;.29%,7%!99/;'*4".;A@HED%,F/3@HG:A?2HD*+9#A35=G'()>("'.B!=1%:E4=?%"
@r2395
NNNATGACTTATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTG
+
!!+)#($+&("!+((!$#!#&**!"%&$')*$)!!*"$+"$&#**#+$!)*$"%#$$$("$)!&#)'&*$
@r2396
ACCATATCAACCAGCTCGCTTACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCNG
+
2F#/,7H/<G/7@2=)>&B;,B<%,81B*@G:A-2%-$::%/:*>?ACG+4G;F8C;6@G&?<!DH'66)$??1G;F$D@%:"6>*(42+027+A1.D"'.G5%&/?E7")7F:"*G17"@1>='4*+B$$'5/"=@)#$
@r2397
CTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCA
+
.>4.%@!9"<74#(E.:;#D+)B-#CEF18DA1G9B9F50-5.H&-=E$+'7G965@*64!@=@"$H":E$D1794,G;$/;?+G,>"D71*E/8H+)G00G/)!1=@%>82+/<&"9C
@r2398
ACANGGCCNNCTNTTACCTTCACGCCGTNGGTGACGTTGGGG
+
)'&#))("!#'((%(*&++'*&!$&"')&%((&+*$)")#"'
@r2399
GGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGG
+
$===?($#4HC67FB#(2'+4'*-41-=3CC,6H9H7'')<B.;H1
@r2400
GGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGNAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGTTGTCCTAAAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACG
+
F0,>0,?>42G$8"0$;':=40H<4&&8-1C*/<1B?423%DH%22)?&&C>1&F$;,<0'8-4>$709>1B:@<6)56AD8/B=?@E@,%<:%&6D&/-)#F="G?;+9;82D"$@A!(10/?-H,0+#'=4!4,DC(#-(F6"4#GE>2.2E99C$,(H<1'706
@r2401
TGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGA
+
G%@E;"3#"!$<$@H:#4C?62B7C>D1-5F1.@6*0,H&0(5*E+D-?+@EF#?(63/,A*%"1@%)'-C;F)#($*.A%"<(6-86(-"D7G*E@6,60!"%9:%.<=.)C5":;+:</0#4H<F1),%!;#:<!@G1-B&)A%%8F(D5$),6):*A@=.&,4D38C-5>'2(6=?2+
@r2402
TCCACGGGTTCAAAANCGTGAATGAACGAGGCCCGCCCGCCGG
+
(++*$+"**'*&("*!!())(%)*$(%*&##$%'&)+##!%#%
@r2403
NTAGGCCTGCCATCCAGTTCCCGCGNAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCNAGCGGATTATCGCCATACTGTTCCATCAGGCGCTGTTCCGTGNCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGNGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTNCTGATACGTAACCTTGTCGCCAAGTGCNGCCA
+
"0*$8#EAH"@E/E?H-8CDG</G63,@-$A%5+CE&9HE==D#H3B$;/=$5:H'.3H7F2:6GA%E-G('AB:=3H17'F7H#,?+$:0$$D!:1F(F27&'!F;$A,8/.H48',*7A&%9%25:#ED#6;2?2%4@20&G)D<4,&<H+!?DA8&&;D9F<DGH2#$.E=F8G)B%;&((;)0%,<0%D93#+E9!/:A(#';@F'>9F%EF6/08!GG"H60.8'99:4*4&976&G&5AB<3-EF+;=5,&"G(-6,BE.,+295A=3?)
@r2404
ACACTGAGGGGAATACCAACANATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTCCGCTTTACCTTCGA
+
?!*3,4D#7"47.3B5:;1$-A@=!0,-&"=2#).E?D2D-@6=DE$)G9;@".FB(@72-"D9>#)-E,&B&#)G9C.$@$9G?'E;-@00:E("H38G.;4)5B=!"BG!)/+.*!E>A"8?(@FBB?B1#7(!EF#;1/4AC<$G(D?8&/*11.$:9#?/5$,'2257/4C>/(!'3%B0"%4B18)=
@r2405
ATGGACTTGGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAAC
+
"2!>1";3;*:@B:2AC)H;C4G4.#/2>G0'+;)!3%F=&A'2D=13
@r2406
GNNTACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATNATGCCCGGCCGGAG
+
*("!%+$%$(%*%+""'%"$'$"$''&&#+)!!"!)$$#*'!#(%)$&#&$')!&
@r2407
GCATTCAGAAGGAGTGAACAACCACGGACCATAAAAATTTATAATCNGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCANACAGTAC
+
1-.@*,G1'(7!*/2#E7/7C1)B=#?7=?0/,>&DB'487+%2!4@;>@1'68"*'6.8.72+28)*@+F!@?F3*6-$,&@>5C2F257&30$545#.B,%%,->!>*.1G1,6!?=8F$'66
@r2408
AAANNAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCG
+
)&#*!+(+**"$!!$$*+()"'**"+"#&))+('&$&'!'!+#'&+%##(!'(!)($%&!(&*+)%*$
@r2409
NAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTG
+
!+!*+(&)""*(+&$#)+#"&"*(*#)(#&#**&(*(&((%$&%*&&'+('&')"'*+#*&+&%!!"&!&!*
@r2410
GAACAGATGTCAAACATCAAAAAATACATCATTGATTAGGACTGGAAAGCATCAATAGAANTTGACATCGACCATGNCGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGNCTCTGAATACCGACTCAATAAACACGGCTNTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGANTGATGGAA
+
$)%%$+!%$%%**('!&(#&)(***)&%+)+""%*#$'$!%+"*%$%#+'"+)#)#%)&!%#)$!)'(*$"'#)+%"&%$'*('$#'+%*)!%(%+!)"*)%)&*%"!$)(%'%&#(!"#)*!"!"!$(!&'"+%!"$'##("*"+"!+#&+"+*#'(+'($+*$'%(%+*$$"))*)(('*'!('$*"(&'#!'&"!%$*)*#*+'*#(&(*"$(&#+#$)'&))(%%!#"&")&#%(($"%')$%$#&($"$)(*&%('#)**
@r2411
GAAGTGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTT
+
#=>.3@(5'C!7<#=290,27D;-D4+".05G4E$@;>9$H!&7?G*?$11%5)%&'/A53'B"'CCD#;0;5AA01<A*5<1)88E:,9(%%!&*.EB+5(-F>8-&0(?#F4$**'?+17!2C@*5G8A)%H>E"=5C)'<A
@r2412
CAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCA
+
1&9#A-;+&HGH(%4:H(A@;6;=C!0H4@G+3&?)596?2'<B?@*G6'40'H*H?+3$6A>A!#%$+$",
@r2413
ACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTANGCGCATTGGCCCGCATGTTCTGAGACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCAT
+
8(6?;!8&BG;79HD(H(A&G5=C'2)+"*5:*E2@)5(1#",78;*<6#%2C6B17D+#""&:=-,;8!+%6.D7G06C@'5)%..*6E7+3,%423F,5#;7!A0H;(B?)##F7@;$71"%*/7$>?B2,?)*")#<82=96,>F0079=@!=C/5/+(B(5GA.#H?!F<,H%941==#C/;;)84'"(;19E
@r2414
CACANTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTC
+
+&&+!'("))"$+))"%'*'$*"+)&'*)()!'(#!+)"%!)"+''''**!+""&"+&)&*'%'!+(%%)!#!(!*#+&**&++#(+("""&*)$(**!%%)'++%%('$!%#"))+&$##)()"%!%%%)')+&%)#('#
@r2415
NTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCT
+
%+$"!#!&+%!+*!&&%)+*+*'*!*'(#*&+(%!#%)%'!*
@r2416
TGCGAGTAGCATTTTTTTCAGGGTGTTATTCCCGNTGCNTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATT
+
&+)&%'&%#*"'(#+"('*##"*'#!+***&*#*%$+!))!"(%+%(&&*#(#%!'$%!+#&*&)+&+$(!*+*'"**+%&(!)#+)(!)&+)'+&*&(+"+!*$"*"*)%+#%+!%"++)%+
@r2417
GGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTCGGTCATTCGCCCTCCTGAGAGACNGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCA
+
'-:3D636*H=($-9(#:4)F0#CDB%:+@D+?)G<!>3F9E>&=4$6&5H7"A:,+0?=32>@#3#5D>0HA83?7=B55?1B@61$E*!92&/3%,7AA))4<D1/)<<?0?71<2.CH)E'!-->!<(@2=/H('#4C66,F+3!=(%5)68<*!17F7CB.:'A)'"C"FF2%;)*#:0BC+()=?&A8G..H4=C@B!)@#:<D&9C5:100&(HE'F?42*(:?;H*;*'*?8$=5<6F5F
@r2418
ACATTACGACCGTAACGNGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCG
+
$)?<,.16+B7+GHB2H!::A;$C15"(#&G'/,*$H.03B(6$%B,!--,A2B)(/H'1((74@B0<*3D1@
@r2419
ANAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAANCCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAA
+
-'#G)1'DC#%3F1G8G%852*<4B':5"5B44DC3$;%,=83(&*%CA%=()>,-/'AG0E?":*7>'?<&&CF"GA$44<"=(#H4F,%*($FD7?,2'2-+:./B-(E6":'*6B-&*2EG'0H**",5(1G17%HF.&H
@r2420
TCCGTGGTGGCACAGAGTACGGCAGACGCGANGNAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACG
+
8#9B..&?$C)H'&D=,D'?>0;2HD8/1-D&A"-,#!'4;0F)*%?3294:29,";?B404->C0E)%HB5,'F2@4!66@>80<6.=$=3@.E7).7@)@;(FH:
@r2421
GGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTC
+
-A$G:%%<=8;CC6GD;#,&)&A?6")(%$+-"*+&-E930$C6>3=16+050((.=9?0E92-57;7&$5$#H&#!6-DH+1%A)2E.8+#
@r2422
NCTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGNAGCAGGAAACTCACGCCCTTCACCAC
+
$%&)*+#)##+'&)(#!(&$#'&"$#$++"&+&#"'%%)*+('&%')***%'('*'*$'!%+&%$)+!"*!&)!%(*$!*+$$"(##""!$&&
@r2423
TGTAGGCGTTCCGGTCAGTGCCGGACTGNCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGATAAGTCAATNTCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACGACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTNGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCT
+
79/1;EB8B0,9:#4E>@;%532;3'HA<50A%5:3DE3'C#:&()1<C$!.=:(#1C!77'E5.G)DA$8@'<=7#G;#$?;)>!/$;;.)'2;4B?74.&-,77;-)A/2@6#.D66A@.FA.)*"7<'1?H!H82!/54';*@$,?#10(*G=B9&+!<*24D<1-C')*2!4$!(A597H"0&<8':$86&*)H!CD&C1$E5&G=/62%!FE1"F/=9/+-73:5=E'(3H?F%(A414;58*G1@EA?.;)$/$=:D,@A(G3DF.88C++,"*<<;CH1(.G6+.2#-/4C
@r2424
ANACAAGTTGTTTGATCTTTACAATGATTCTTATCAGAAACAAGATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCNGGTGAACTTNCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTT
+
'#A",A?5&6H/>F)A7",@40.0+,G$(**5/D@%58D>><5!(/->60A8&BAC%.,8./3;1D3/.!A#B<C5GG85,%@93.!.@?:7B"6HEE)1"8HB(95C*3'G!B5>5<C;!@=G4D!H!A19'/.E:!@#7%/:BF2>GD"C1BGH?",$3/=-8@*+C2'8&6?/4%B:%F?=+%9%-8GCH8#$<F95@>3:.6+78B.>(&DCE&(!@3;?G:!A&AEE/94@$<:->+&&C@/.=F)4
@r2425
ACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTC
+
:+1%;0#0/6;F;,"<)-36*9;E$&#0&FC,-6*>/!>*12%3%34B$.'+$/G2,$2
@r2426
ACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTC
+
=#<1A/46C#+94EG"%23<7E,#"FF&B8F)0<;4A5'-(*',2:!HA?5"H@H0>5=+<0E
@r2427
AACGGCTACTCCGTGTTTGAACAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCA
+
;H&>$/G&D,CG?02&D</F21A"">!8>=8(A<F/GB-0<@.(5%55$.<'<FH66)-3<(4#*(>0H"F
@r2428
GACNCNGGCNNNNCNANAGCANTNACATNTGNNNGCCNACGNNGNCNTANNNGNGNTCNTANNNNCGNGNNNGTACTNNGCCGN
+
""!##!$$$"$#""$$"$!$$$$"#!#"#!$#$#!#"""$$"""#$!!"$"""!"$$#"$#$!$$#"$##"$"$!!$!"###""
@r2429
NACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCGTGAAGCGGCGCAATATGCTAACTGGCTACCTGCATCACGCTTTTTTTTGTTTCTTCCGTCTCCCGGA
+
#,E#C(2<7&)@G.9/%(D14(7!$;7!5.5%!0G'GB=88*'&C,>+,"26D,7/$$*-5$)G'.-*G!-'19*<:HC5;DB.:#F#-B4;46>&;5C;,F0(*5B6$D#A>E8;%"=73BE(?3693BHE:0E<C:01G%?=>;FD;1(3GC8+.H>4*CH>A9+4AB(:"#?F96-C>8+(,#G??G$)9>C=/F@)&H83#.,:
@r2430
CACGAAAGCGTCAGANGCCGCCACTNCAGCACGAGATGCGGTGGCCTNAAAAGAGGCAGCAAAATGATCAGAAACGAACGCATCATCAAGTG
+
+@#$+7$@.<!.*F)D&#%-B,0.D7$(G*$3!&8*&2@&=1.E!>D)D6CGBH!+3%&$%@3B*.5<2"=<@-6GCAD-,'F<?1<B0:F1
@r2431
CCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCA
+
,)+9")846$7;A++/=6="B,**E,-8D=""&&1;(E9)0$=C0A73A7F&$&1./>8+,/2/ADDCC#7!
@r2432
CGCCCATGACAGGAAGTTGTTTTACTGGTNCAGGGATCGCCTCACCACGGTTAATTCTCGAAGTCATATGGACANGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGAT
+
@<41H7!,-36HGH7=/71H237,*F995?!B@!)"34,%7C/.,<+$8=#3=56"D(7)>BE05%.;#55>,*+4-@"3>2EG-2'8*<&674"'D)*)'-$-(:*">9GA@<+?6)/4ACD*"7)*0((?(':H62
@r2433
AAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATG
+
E!*&:55=)8A(0?5#G&)*A)?2*/F>=?+7)="A9.";
@r2434
CGGAAGAAACCGGACGTTATGATNTAGCGTGGAAAGATTTGTGTAGTGTTCTGANTGCTCTCAGTAAATA
+
CA*7#7?AH+)+9$8*0A#$>-@2CGG3';CB&0!(+2HB)!5E),C<"+>@57.5+496@+1G8;!4@4
@r2435
TTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCAT
+
%3=%>'1"?202:F7&EA49)26.!A799@<!914FB9$5$C3@,*4DCB9="36-?
@r2436
GTCCCCGAAGGCTTCAGCGCCCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTTACTCGCTGGT
+
9D2(;.()9?'2A=:#%(#6.GG9:0+,C497(:49#=H.H1;G!C20>&1<#4/5>-:H3G8;-0./BE6=1.@2;6,D>=G#'@EF;%+@%9;@EH%A>16#.?A4F-G:2B&4*1-?H9BC-7=C)A,1-8,#A-
@r2437
NCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACAAAGCAATAAAAATGCGCCGCCTGAACCANCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTNGTCGGACTTGTGNAAGTTGC
+
19/'"-G@=.1$5"H)+@D($!)$/!?5-:)-%>'E.D&>>AB6"4&<77&;/410?(D>:*D8>/"$*'+7-4.;'.>B7.7)@2-)(@-2GG$'AG*D/.*:-B(&<>%<,&,GG3A1;9E/C!)HA&/#4.0F&#-:,E%+=,91"?!5H#9C!5%(#!6(GGB.DB9GE(-D(%&7E7,*;)?E!1&
@r2438
GACAAANTGAATAAAGAANAATCTGCTGATGATCCCTNCGTGGATCTGATTCGTGTAAAAAATATGCTTAAGAGCACCATTTCT
+
*5:?8:5H<#,EEA'F8G'/)&AA%A*&:%)G3/1F'&5*565%>-5+02=.,<)'C5&"(#0A/1+)(;6B))<0%?*-2F4@
@r2439
CAAAAAGAAGAAGTAAGCACTTATTCATTAANAGATCAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCNGCAAATTAAGCGATNGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTG
+
308.)5>86#9=F8$/:F48(%<;>1-4#0?E*-EG9/?*E2:+:(8/6<<2!7?2B1.47+2!6G&F(G?2*7E17<G2-*<H:@,)(,-@=7<';*"!)DG.3<2F(:F3H<A05)/&3$G=$'675=+<@)8+36AF2D.//$/&%?(=#<!+C,<:#+'<40,01@=,A,-2.,4=B;"E5-@;@6
@r2440
CTTTCACGATCCCGTTTTGCGAGTTGCTGATTCGTTCGCGGTTCCAGANTACCTGCTGA
+
GC=BEE8;85@A?=;C0087HHD>$$=;<#ABE=6(6(!%?A&68>4&"#D)'8F8CCE
@r2441
CNGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAG
+
$"*A=+*D$<7#-"?H/,=)"DG*!(F*&'A.F?A1#<>;5=G&>?F8$>
@r2442
ANAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACG
+
%"H>?5!"0E+D8B;/A*')!E%.4<<6G>AHF/DF037;G.4F;9(8/!E+-":C/)"'B2'F*7F,*,2.7B?::.9G+9HH!CG4FH?DE0"%H$-7B$<@?1-,.(GF
@r2443
TTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCC
+
)AE8<@G";BA8#60+/.5%5H6?%17G:,%@;2?2'4EH<
@r2444
CATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCNCAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCACACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGNCTTAAAGATTTATCGCACTTGNTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTNAATCAATTCCTCCAAAC
+
E)(&12<2:,:1#*8G!#;BDC-G=G%6<=<=5(H5=.+:)0&@915E;(H(,;EG7!73&C7</C&8:?)(7*29@#'0/E-$%">3C-2E-'21/F9.A,'13%:)2G(1,+3)2=%B1.+:"AC:=&1%34>3F5E&H4$=;*:*&,'>=0"<H>+"$97>19,+@9@2!#(C'?4?H2%H=/>A("G6(AE:E*<"1:8&+62.*=$C<B1F(50,$.<-,4C89B)#"*848EEC>#"H=;E7<EF2%C204-8-@'<C0A-&4?)1%$7;&D9H+;9D;5H&<=5F/?38?"9'/H++&D?2D+6B==*026D-3+!"*+CE3&>+38*$(B=81G-G9AA-3&?!8(6;
@r2445
AAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAA
+
++('**($%))+"))+%""("+)+(%*$$(%*%%&%(%#('
@r2446
GTNGGNNTNCTGCAACGGANAGNNGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTANGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAG
+
$!#')!!&!%*(%'*)$$"")*+##"&(+&(%%%&#'*#"%'!#*&#(&&*$&''&+!*('!$$*!!)$*(!&&%+'+)+!((!)%%'#%!'#)(*$)!*(%$+'($&+$(!&''%#%()))"'#"!*+')+$$#&'%#*+)$++'&"&')&!(%+(!%!)!&%&+$)%'%%!$&#$#&("%')#$!!
@r2447
AGTGCGNNTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACNGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACAT
+
&())("$$+&*%!'#"!%#+#)'%!%*'&''#$'$'')*(*!*('"*'$$#(()"(*$&($$&!%$)&"$'%$!(&(*$!''*$''+(#&*$(&!)!#!#+"#&
@r2448
AAGAANNCTTAATGNNTTANGGCCCNTGCTCAAATGCTGCATTGATACATATNTTGACCCTGAATTATTT
+
*$**'##$#)$)!*"!)%'""&+**!(*!!"%(*))+%#!*!!'"$!*!&""'#"%!+'!)'"'(++&"$
@r2449
CANCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAAC
+
'A%FAB@$",;4>?F6/+<)&?!E%<F.H1A5/@?8+B)6
@r2450
GACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGNATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTG
+
D2+$C"/$.B%*@>.#D,1D5;<F2;,<'-?".+(+-B:13%9#D(81H/*9#:2:+,9;/>B,ECC0H&H,*24'(D1"@8')/$C9.)%=&E*!$#D/EAF4/=H7)+:+&6E:?1GA("C(>@*
@r2451
TTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCANGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAA
+
G!'A#=*5='?45,6C$=>>GAC@).2G!?(.,F,8D87$*1%3(<+5:,:C:/0,F-$>DB)319%7F:?DB.;:9(CF+5),/#$DD"C>#G02':B;D.<:#+55&7(9<0:2-1(E79BB7+?F&'G
@r2452
GCGTGAAGCGGCANAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAA
+
+AE;7E*27H5!(:'+A838+;;?"11$:+G9-:?G'E!!*<'-;9-:6D'*)F54$)%#1;*>
@r2453
AAGGGTCCGGGAATTTCTCAGCCTNGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACA
+
48"/7"9?.9'G0FAFD4/%(7/$#=F$@H!)#=2G1';/A%8+E:B<D2F'D>E6"&&BB$>F@4F??=0!-9C<;:;E12+./A1>:49&)2)'.48=FA25(#/+"D0>1C24<'D(C;+,5(C
@r2454
AAGGTACTGCAAGTGCTCGCAACGTTCGCTTATGCGCATTATTGCCGTAGTGCCGCG
+
=$@#3DB+:C4?&C.<(G'%3>(#7*&=E7!?9,!!8EF9EF8E77/)<2;D+5*!5
@r2455
GCAACACCGTCAGGAACACGGCTCACTTTTACCATCACGACGTCGGTGACGTTGGGGGGACT
+
/!#F(:.317EB771>3?9")H>*!/)8.-*.'C>$:,>!?&*F.'D7,D:H2-#11EA"?6
@r2456
CGTNGCGTNGCTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTG
+
'*'%*(&&)!+(*#*+()$%+%!"%"'*!"&+%&)!*#'*#""*''##)#'
@r2457
AGCCACNGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTGACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAG
+
%7GF;*G91$>H(3E3!#?*-,/='%:#;F<3!;FA7>H<DF('(4<EE9#GE-#(:"68D9(E0:9A2&#<@G2&#=ED9;!>H/(&2:/B@'74@"$&3&9=A2&(,2?$70>H&66A1>)-$GB=H>916=8@C=.5,(+>%3&.F8=*H;H$=HD1F/*-.84<(A.,4.9AG@(?#$="1+,D1$7286+HE&<!)H>@$$)!'*'41#5<>!03
@r2458
GAAGCCGTGGCCCGCGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATT
+
A5BC9,#G7C3D/"F47@+FG0FF"4A/)3H;GB<HD%$(7"4"')E1!@7&47?
@r2459
CCTAGCAAACTCNGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGTAAATTACGA
+
D'>,&E-8&:;;:#887<C3:8-8;D2A:EDE=//H>)B0CDF5E.->#/E")";-$69(F-$*
@r2460
AGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGAC
+
3<(EH97G8H!;E?E(%F1%A="$&G($14*#A015H+<1=9>FA(F$!A6B:/1-4>>B)G4@)6==!<
@r2461
GNCTNAATATTNTNTNNGTCCCATACCGTATAACCATTTGGC
+
&'&*"'('&)"!%"#$!!'+"!+%++%"##'&)+%)'#')!!
@r2462
GTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGNTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCG
+
@<%A32#"-D1+<FC+D.#E35),(*H-057)(61@.-8G!3;5,(#&/"8(B(B,A2#0+3,3(=9<<4*%1%/@G1-;52""*F&9&%".=0/
@r2463
ATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAANTGCGTGGACTTCAGGTTGTCCTTCGC
+
#*H0).7B(=<D8$HE?;"A%'@F&74$1G:><<-A&@#%8H79H?F@#:7%<6"73C+=2D,D8F/9,)%8.05B(3@=F
@r2464
GAGCAGTACCCTGTGTGCTGGTTCCTTTAACTGGGGATAAACTTCCTGTAA
+
"H@"@"!.:-)=1E@5C#A$A>G#E6?69&+>B?967E*?B2%3B$E4F'2
@r2465
NCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCC
+
'D*,8>90:/;;(DGF<#-G&B%D)/1<+>?'@!G,%5A82#H!F1>->+.-+2$/)623&+!*/7:%,;H13
@r2466
NATGTCAGGNTACCAACTACTAAGGTTGNANGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCAT
+
#&**)(%&)##+(#%(%(!$!&++'"&'""#*(&(#!("++*+"*"+!'+&("'!!#$((#(''$!%!!%#!("$(+")+#"+*&(!"+#&'%&)#**%'*!!+)#*%$*'&''))+*%%*&#++)*#+&)!*(($#&$(&'+'&+%##$'"%)$&'$
@r2467
CAAAAAAACAAAAACCAGATNATAGGATATGACATTTGGTATAANAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTA
+
1H*?4D4(H//B'/$-6($'5($0)"-%-.H>.@/<@DA7H1=2.2D15H01(E%#F+?E<>!78/D9B@=F!2"0,.70#;(H>),?;6#'5HF"364,1A2;5*=4C.8,%G016B1!!?$;3)/.9A206?2*3A:;+FHE+'DF9:;HDC30A-*1)$-*;*>>'+1/G
@r2468
TTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTNGTA
+
3>F@D%.>3:#B/,H"3*A5.8E*:FA1#'0<F<5,:F9+>:C&1=@>/G5D
@r2469
ATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTCGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCT
+
=2'..G>/6<<)=?17;60;*A949-8D$&4BB,6*CE//2#=1G?-)G<CG)02#-)2'&=#$1;F'$*;@<+.&?,<:/H%9?2F***4>A/C'C+4<-311*A@)EA-103''G")">+1:C*3;.@!30D?4=&4#H94;A/9B;C;H<G@>(;10C?<><?"$E40;),3F1-3@=E@H44D<?H%?"&918HG.E;#+%..289EBH;8&?8(-8E
@r2470
ATGAACAATTGAGTCATAGAACTTCCATGATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGACCGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTNCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACG
+
.&*++DA&(6C3*0%-?,")@)5)8?27?/D9;,9+424)E.$6D$1"%%77C@($.1>++,*F4=A6$:":*G&C#AA(;E$F<,$;20*E?@@393?+5=(<AH&('2D)8(1@B,"/8G4C@;';<+:8.:C<&74"#!%!C"E1G4ADD@00$C+4=2++A)%*F/CF"%%.0/-;*F82E*6+?4-:/6%A#E&$
@r2471
GACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTT
+
=3:&H?)9%!E0*,B*2(E&G#4@<C3C8"<93>@+(?G+!&FH1CB;8:99/.HFAB?$@/',&H2A):(7.HC&2>7-/3$/>5/64@9B@A0A&)/>@;F.#,2'>BDD*F?65#&(,9(4):C'#3"13'8&%?')<1//"G2/8=#0B@#>!/'E7C%
@r2472
TAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAA
+
8/-">($-6.:A<*F'@;=)E:<?,B4H)@/B*3'>&G6HB:0*67:'D
@r2473
CAAAANCATAGATTNCTCTTCTGTNAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAANTGCTAGCGAANATGCAAGAGCAAAGACGAAAACATGCCACACN
+
&)'+)((+&%*!))&#$'"(%#($!#*&(%#*(*+)&((%#)!+'!!&%%'&!&%)$%#"&#)$$+!+#%!"'+(&$(##+$%*"&('"!%##&#&%!*+$)$!"!"%)%'+"'+%"%*(%$%""(()*(*+*(&'"+&#*))$#'!!+$)'#&#$$+'&!"*%$%+")$$%$&+#)(
@r2474
CAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTNAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGNAAATACGTTGATGATAAAGA
+
*-()E*D8&D'F,/!6E<'-9H3D;F@503E@@&5?94%GG9G5&:$F=*<>$4G%%;&CA(<,.&-5$D!*$9"2/=B*$7+3BG-E2)%$%2*8ED)1!,H@;#2275GG2.,G7AE><=6'!0:7=2!4-0?!"E?2&)4)"%4<%AD+2E&<>7G3'3)&>$9DA/&'92C><<%
@r2475
ATAGGTGTGGTTTANTTTGATGCCCTTTTTCAGGGCTGGAATGTG
+
;22-/''<#!:+3!;<;@'DE'=>.G!92?)/*;-?:?4$/4E=3
@r2476
TGNGATGGCCGGCNGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTGACGCGCCACCTCTTCCACCATCA
+
)*&"+$'!"#&)+*$$)+$*'+$(+!+'+*%+"!'$!$"$(%*'!(#'"*&%!(*$"#)'#)'"*)%())%+%!&(#'"*&
@r2477
GAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCANGGTTTCA
+
,<120),0%=)42C?0D95>=$*!,9H#8C)7&+8;C2#7E.%/'D)8";@*ED;A9:"3%7>E9>8
@r2478
NGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACAC
+
)4)(2"D@E8!4HF=,*8-;/>G(@!G?0D>%&:<57792''4
@r2479
CATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCNCCAGTGGTATTTATNTCAACAC
+
C@.E<.?97+44<"D1C0?H:;+2H1#H,A5$4C%95"DB7*#B0-$2A.G#2C756=BH6H()
@r2480
NCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACA
+
&?7!F#9F%?/;2H/D:5)C=/5$62GBG=-8'<70<#9+0;7B=D
@r2481
AAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATNCCAGCAAGCGCAGCATATCGCGCTGTGACGANGCTAATCCCNAACCTTACCCAACCCACC
+
.1)%(;:<+D";(;F/>.EC,@<5-/61%,3DD289)CB3D04A3&/:4*+29/*8"G%34-8G333;<H'#2D?.>&.1=$>-6'5@,!:6;++%BH"61F.E>'(/17>F,G,HE9=#"%B8)7$3FF41
@r2482
GGNAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCNACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTA
+
)(!*+%#&#$"*!!'%)$'*!#('"!"%!!++'*)&)+*#*$!"*"!"$'!'&!#"&*%$*'+"%*)+'!%%%'&#)&("#&*'")+""!%*(#
@r2483
NTAAGCGCTTTCGCACTCAATCCGCCGGGGGCGGTTGCGGTATGANCCGGGTCACTNTTGCCCTGTGGCTGGTAATGGGTAAAAATTTCTTTGCTCGTCATNAACATCCCTTACACTGGT
+
!0<,@8+6',5?7B:;B4/#2.)5&G-;E0;CC/D=/3+<8G#(&-.$G%:</E"&#9(89-1!@3A)6@61/=8D!-864EF"A"CH(C945.(*D4/D+';>?@+E&*>&1G$6'C,C
@r2484
CATCGGCATTGCCTCTGCATCGTTCATTCNTATATGCATCCT
+
66<@A0?5+:?/5,@"B)1.=A>6)>0)&?/2:<9.>65)EE
@r2485
TCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAG
+
!18'1@#!9F4.CG81C+%9*.363%;C&=C)!01,'>8B(=&000"E0F?#D864-6<!6$6A*2E(:?3)>/!0D&1&C%2G4$:%DD1D?@6<AD=%AA6/9B2
@r2486
GCGTCCATCCGGNACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGNGCCATCATGACNCCGATGGAGCCTGTCCGGG
+
G)?0:C0"#H+/.F-2.75&>C)?%.!%&2:;8=C>(2?,!F<*0,FBB'9!(755?@6..>D&H=,>=<;4(-:5CE(7B/)?>@@BE@14A/7(C=.>#F1;='B+F46FC/2";29.$-3=#/7.(/2?C142FD7<G$!"D6@%%)!FH!*)-E)?-6%:1>:0$CG6
@r2487
ACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAA
+
/-:0,<H7D,#F@,!"#G&>?*$++@9'<BA,@26&04,2!3
@r2488
CAATCGAGTCAGTACCGTTGTAGCCGATANACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAA
+
54%H6%2B%.,5$18,""8F,$$7&,G(18B;3#780:84%*/A7$#@,43!!(&%G?%:?=A22)5%0-A5!B9H#)&&07503%+2:6
@r2489
CTACTTTATAGAGCATAAGCAGCGCAACACCCTTTTTTGGTTGCCG
+
194H-E4(/1?9+H4#.97,)@C'2&5B:"&"&7:>6+C)A9.5H$
@r2490
CACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTT
+
B59?@0;!4G(<82.D?(A453=68>F%3>(5'/5?!!8>B1;+&0B2+?0A>1C@(G(*=6+)3*":&@""<C0HC"D18@:,GHE/HB8<;E)*+C+5$+#'#E;..5,5
@r2491
AAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTA
+
/4BF8G8EEC/7,EFC5E/7/85#BB(4A&<DA=+(">&-5;3A92B#=%F,3<"D&,&"403&*8,6HE.)5)$H$8?
@r2492
AACGGTGGCTGGGTGACGGAAAAAGACATCACCATTNAGGGCAAAACCACCTCGCAGTATCTGGACTCGGTGGTGATGGGTAACC
+
&1CE'2(DH2.@#?$551G:BC(=(5D;927?3*F4)A@H:-=13"+#6/F&"E&C>H?5<562,)8!"&HC><1A5))9">$!6
@r2493
ATCAACAAGGCCATACATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAG
+
$,#($55F)@F.-$'E.)/09<8,#>&!?65)E@"3:%G'>9'F3>*:0.HCFG&=3DC%@<&)=&-:B;:HB
@r2494
TCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCT
+
/H$-71B!%.;5.2CC'2,DFC1DA+G6G,3?#?A=:>,DF(&GF-786=H01A!%GA@E&.8)#/$
@r2495
TATAGAACATAAGGTGTCTCTGGAAGCTTTCAGAGCAATTGACACAGCGTTGGTGAAGCACGATAATA
+
?4G@+9?';2)+*<2AA(;8A7-A"0@2HH7;"F5='(F<A2H381F$*4B4/A%#4)A-4H.G(-!.
@r2496
CCGGNCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATAC
+
C1@7(GBA1"=13-H"'8G5H>,<:9(=.8<;.5D,1@8%'>9(>B3=(<2A6:!%B/-@3:>?,:!+H@&*&%'@1'*!FD&E1
@r2497
GCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATG
+
B,%D%+G8):=#'5.9"1#;9FB/2."B7004($/96+@:G"4;-:&F(D7$>*B:-((?":<=FG16
@r2498
GTAACTTNTNNACTATACTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACNTGTATTACAC
+
(%#&*!!##!!%$($$*"'+($)*!"*!())*!"%(!(#"*$')!("*"&&&*##'++%!"&)&'
@r2499
CCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGAGATGACGTTATTCAGCACCAGCGGATTATCGCCATACTGTTCCTTCA
+
7A&G1>B"$5?6B9BA60<36=6!>F?0D2;7D:/5=8:?&@&D#E<D>DG,&%&2%#5F$DD#E+?90;9G1#2"HC00BG#*A/%@EG5.:!:##,
@r2500
TAAATGAGTATCAATGAGTTAGAGTCTGAGCNAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTNGTCTCCATGCAGANATCACGAAGGTGTTTATGTAGATGAAG
+
?F/CHC>;4<)&)G'(?4B+-BF&FGFF?>11''%'7(49GB'://>@AA?#5F/C-&%/449?;12%#&!/H-,@,H.'2/<!7@(E5A1+*:+6(.G"G+,,)<"8H/<B7'3
@r2501
CTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATAATTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATT
+
*-?@&EG)6-%@01#67>E,!3GH<0*G&63?*%?*=+!@.-C-+?0),,+7D+'+BA.28CD0H4B=0-A9DD"&.B4!@3GD;B'!,F6#*D*D%,'764'!0<AB6C-A"GD)0.4=/$;3/&F8>!C;7B/.773
@r2502
NCGAATTAGGGGAATTTTCACTCCNCTCAGAACATAACATAGTAAATGGATTGAATTATGAAAAATGGT
+
"&#+()#*!#+*+!*&))+&"%"((&&+($)))$'&*'*$#*'"&)*%'$)'+$!&)*'!*)#)*+&'&
@r2503
TCCCGGACACTCCCGCAGAGNAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTG
+
>H/*=B(7E&/172G85-<G4%7=(/*A;9D2A#F%:G",B&><D&28<7G+D5?&#>09H@D$5%+!9/<06@;/(<)0D$(&
@r2504
TCAGTAAACAGAGAGGTTCGAAGTGNGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGTCA
+
/3<?5B-4).3,?,&F09%C*-#BA<3*8G&F59.&GD)4>"?6'-6A'")7,,##!+'E+58$<9FC6*
@r2505
AAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGA
+
A';<1.-F7/02H3B%>C8!1F?7$&#54C=;/#,FC%4A.2<G$8:/C0*:-@3F24/(1:A388B7F!/+?12GCG5&<$5'C05C@,.3:53(B&HE6
@r2506
AGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGANGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAA
+
C8GBF'F;%H42E?=.4&18H0?1;"5G23AA0E2!5:".<>>/+>'!4>B*3@FH:25!@1&G33"1<#+FF8,D=G;2@'-9+D%<,B5G2#G5B!(>;9,&7E?=.8)0D>2*#4A$"=H%G=,,C&$;?*E%3F.E1%(((9C.4".+,+."FA+!F!D@B:&#HF81#&*-#=*@6*?9>+"8==)!;
@r2507
AGCANCCNGCAACGTGNTANGCGCAAGAATCAGCACACATGGTACAGCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTNGACGCCAGAAAATTAAGGGAANNTCGATTCCTCTTATCTAGTTACTTAGATATCNGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAANTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAA
+
!'$*"&'&&)&!&'"&%)((+)!'!(&"#%%'$)%*!))*((!')+*'&#*!"+$*$"&&+#($"(&&'*#&""""#(*)$*&#))*%$!)%$#*$&#%*&+*"((+&%"!%'&'($$)"'#&&%!*(&"(!(#'%#%%!&&+('#()&*'*(&!&""#'"*((#**&*(#$")")"$&")#"(''%+#("&*!!($'+()!*&")#&#'###)'!)()'*&*#+"'+&#""$)(*+%%#*&*%)!%&!)()++$!")($*'#"!#%+#+)$$'%(($*)
@r2508
AGTGGGTGGCACACANAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGNGTGCGACAGGTTTGATGAC
+
D;HE>.,$+=(H<$@+AF$:A0#8%'D>$;#DCE,/#595'=@9F"3&H$E'"1:H!,H6(@6%4"742"=H9)
@r2509
CAAATNCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGATTCCTGAACTTCTTTCAGACGATCGATGGCCATACGACCGGGGCCTATCCAGTCGCAGTTCC
+
,F*"D1+E,4D:"3<;!B+(,=+?B:$34:'*A),(=*&AH8;>!/&.>=!':"'4;4=F!9%C-B1A?*E6/<$8)-B;)A**FA6&1,?)#5<33.BDF8534A:1G<B8<(=C47)2<6C@2*A<"FC49*)0<H.DD/(192A15:)/?/($%7>*E'+?!.A!@7(26C.,<C3:519#(-7@4$ED;5<+134,@E5=9+HH2!=B6=F,EB9
@r2510
NNGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAAATGCGTGTTTCTTGAGAATTTAACATTTACAA
+
)$A#"*=?):@<6057%)-E'GG(=BD#98F,/?<)5!G>?4,7;:%>/HB%F!%3G:'(=%60>&<B6B/&-"6BEE
@r2511
TGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGANCTGGTACGCAATAAC
+
$+)!*('""+&%)#!(+!"%)(%+!*+)'#+#!#)$"("+'+"""%&)&!$&)
@r2512
ATGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGC
+
$=.A86:0?F*3@9?@;)*B?.F*.#'B52<760<FD"F$'H6&;>'*!,/+5>A?8*-+<E,8>2.!3A-5.;
@r2513
TAAAAGGCCGCAGCGTAACTATTACTNATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGNTGGGCGGCGNTGACGCCTGTACGCATTT
+
(%&('+*'%$&*(*)!+"&')("+!)$($&*!$)")**)(!('%&*+#'*''%$&#(&*$#"+%("%+*%!#%+!")%')!+!"($"#%"!*"(!%"$"+"#+*$%
@r2514
CCGTGGANTCTATNGNANGNNNCNGACNGNGNNGATGAGCCCCCGTGTTATTCGTNGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCG
+
"))"*&"#**&%!!"($""%"!*")'(')#*(#"+*#"''*!"""!###*('"'%$"#%"(!!#+!('#+'+$%)"$%&#!"$%%)+*$'($*($(!+(*)##*+"##+%*!($&)')$"&#'
@r2515
TNCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGNCNC
+
8#F*F/6B9A',66-!DD<*(0@0??(DFG':84E479<D790$8*0-)>6&=?*
@r2516
CTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATT
+
-6)!A93."8"5.DG+/=#:$7:/6!B5!"45-6-*56&5(&'HA$;?<&8HH)%3<<;'=:F%"2@)#G,#,0)5(
@r2517
GATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATAACTTGCTGAACTGT
+
0-@!)6?B-/23E0.$-8,.%)>'1:=.?D"//"#2/*F;G(";.?/0EC(-D:-&@2!$,8;25D(>)%+4061+6.F"GHF,11-#&-B$F4!D:DE#>-HF*E
@r2518
GCGANCACCGTCATGCNTGATGCACTGGATNCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACT
+
E$)@362H*E"908(F9B45<#?070/!D@2@3''D*D$8.-<2F1<4FF#!$-@12HA.#@G1-&>;D;7D%$E;2:"31:G#1,.3%F/-9&G#F4G
@r2519
AAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAAATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATNCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCANAGNGGATGTTTGACATGTTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGA
+
G3H%H;<4:8@5;3?&6@381<.B',<?")<G7"215@''<C?&C'%>$?+:9>'H9"<%1.5*1#3:%H??#61*D7H1'8.(6.2=3-:?)*)7&G2=#2;&<4@>A*2=3<0;%4%37D,3..2*).@&=.;3"%=#"68#!&*-.)/(11/,?2;/D9?&9,=H3((9C+9>9$!4#!<7/!)372"8+1&=>&<:7?B#6D/>7(1+;2?".D.6EEDC<'17&H2E/+%9?#$&#3FD&.7A9=(46GF#60B7#8(9<86H?>"7(,$3"?//CCE-+)&>,-&(2D'C%2-;D1DB271+>+C+
@r2520
CNNANATNANNCNGAGGTGAATCCTTGNTNGGNACCCNTTCANCNNNANGNAAANACNCTANNNCCCNNNAGNANNNNNNNGCGTGNNCTGTACNANCNNACN
+
#"$#$$!#$$!#!#$##""!#"!"!##"""#"$$!$$"#"!""#!$!#"$!""#!!#"!$#$#$#$""!"!$##""!!!#$"#!$#"#$$$!#"#""$"$"#!
@r2521
GANGCTGNTTTCCGTCTTCAGGNACTNCGTTGCTTTNCAGNTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTA
+
%)'"(*&+**(!'&*!((*%$+*%"'+#!"(((#''''"%+"#+&+(%'%"&+*$%*+%!!(')!*'!+&#$!!%""*)#+&
@r2522
TCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTNCTGGCGGATGACGCAGGCA
+
1:C@)!2+'A:9:-6130C;@4%5:A5*B>('(&/'<:&&"767B(.B863-?*"GD(:*=(
@r2523
TAAGGGGATGTATGCCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGNCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGNTGCGGCCGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCG
+
4%'12B8)%HG@$2"=8:$7:;$$>$3?D18/"-;)DA7H-*80A5579-,+;A#?D)#,H4$EB:2BB?6#*G%;);69?2<8BC#5EH0*>7E92&6@:B48B,/"83@788-0D($B<>6':/-!(G*#5!4,2$+<D0*)#)<)2:=2G2=,=#?0!%4(#&*"&'&,GC(C()-(A":+&#E)-D$2@.DC#,?=C':<&41C?1./
@r2524
NTCNCCAGCGTANCCANTNCNCCNTNACNGAGTTCAGTATGTTTCATNGCTTTATTACCCTCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCAC
+
"&&!)'#%%(&)"%"(!*%)!!)$#!**!+#!('!#%**)!#&(*!%"'"##*&())!))&'"!#!"%+))*&#"+$!%#"*+#&*"%&%(+'&!(*$)!')'#$+$*+($
@r2525
ACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTA
+
$2))30B%77-BH83,5916=>3@+$3CD&.'#AA3$B6:('$:.?+(3!CB7):17/@9+CE>-%;F
@r2526
GTAATATCCCAGCGCCGGACCGCTGTCATTAATCNGCACACCGGCACGGNAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTG
+
A3:AA:"=G=FD1F247H69G,2/E263D19)<;%+28.7D8#DEC8+9!4A?C>";-5;41G)+'>*1$:A4<83293"27
@r2527
TCACCCTTCACCANTAATTGGGGAAGTCATTCAAATCNATAAT
+
%!'*"(&($$)'"(+*&%&)"+#'(*"*+++'#+"!%&(+**#
@r2528
CTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCNCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCAT
+
F<09+(CB.,#5$9H6),5"1>#<,1<)>25A$=FG56$===6B&3@5;3*0%#&:G@?=.:*C@=9*/*E':"EE*A.3!+F'=@;B-H)E+384G!;C(D.
@r2529
AACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCCTCGCTGTGAAGACGA
+
C=)1-A$0:=&-<':+*+(.F.-#!!C.9)=)@H*0E*D)097277<)=.$:2&@'8)F-D/@
@r2530
TTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCA
+
7@$D!C?&<#3@6:%)!4-&F5>)*<&!//C'+2;F@+2G&>;<9C'354D&;G4>98>GF=3
@r2531
ATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTA
+
,)F9/H4!/3HB3F-?6&#&8EA=,#!69"E1G<&D";1':AA%F&6
@r2532
AAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACGATTGCTGGCAGCATTCTTGA
+
%*)%+%#*'+")*"+!')+)#*#(***!#($&#!#!!"!*+*%'#'$(%"(%$&("$'$!
@r2533
AAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAG
+
/%=6D98="=5C%6H13D&73.822%)?,02B,9H9>52D3
@r2534
ACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTT
+
7=-;&$F'!4=,%A,6,0F?C)H!40-%9:2650#%E)07/9.=/
@r2535
AATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCANCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCC
+
#C,<9GF,#E6.'HA4#6+&:/AAAC,?&)D1>%A:A4H3CGD6$C"1'-0,&E$76#=,%<0(57..CE'A$C$6!129+B*(>8&D;2'8!*9!3CB)41&4F**.&:81-8)-5-/D=/#9$%D>58<:?)H5*AA%),?-'::&(:8(!%B%:!*'07HC-D;85E@99""CD&0@$C5+@:#-@29,??,!1)6;*'+EAA5#
@r2536
CAGGTACCCGTACTGTCACCGTGACNGATGACCATCCTTTNGATCG
+
;9-/3A>!G@".(7*E=6%69+B?(C..*)7.;%6:!D4:@5$/<"
@r2537
NGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGC
+
-884C//40,:D;G)%G9G2!#076A&0D2*=971@>GD!+4<-+)#1$%$DG70<D='B+E1F9<A<(D"E?82.!<
@r2538
GACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATC
+
HAC07@8,<1<6&87G4$!B=7*/GF3.E=#&9""+!B1%"C87,%7@(;#B#D:F6*,G45@6*
@r2539
ACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATNGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGGGCGCCATTGTGAAGGCGATGTATGCCGCCACNATTGAGANTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCNCTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTAC
+
,""1%F<!.>2$H#&%./,<=@6,:*F@D%C4A?@78-@<4*.:>!8:'FE7)#":67>("<3$?5A@85'=-E=.3?>G#4)/.7E:502,%@!)A%7A15G78+>!?E3H.>D66/40-.%B'4+0#++4FBD9(%D$B34>5$29E7$"51+09)1&@*(-1-H$44!0<2(";970<48?@0>&4H:%85A$-FB-96'!*%*3A.D)F?>-C1E'<B>#'==,:$68#!7H04F&?.54,560.4$=;/69,?+8/#F/)C!/D-,EF<:,=6$:4,>C"23@;+#@4ADG&3@<.1<%=;&H,7;0CE-1:'?2B$%(H$>7.CB'B74HB<.&%5'H:CEH2
@r2540
NAANGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTCAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAAT
+
&#'!"+''!('&(*$&%'(&!#'"#('#*"$%+#)'+!!&%*$*#'!"!&)*"(%('!+#*&&*#*'*!#"&(%$#*)%**%&(#$+'+!)$&&++
@r2541
CAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGNGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGT
+
:'8B<51>2H$!,1<30*#D)0?&F+G.G,85&0-D.742=0:,6E<F;=!!=B.(G,B?+&1D69407'!6<%A+H)G!0!7;=D4!;62+"+C'5CB>#&=&?D)5:*)8AH::%##*C4E&<131?-A>"HB,H'*537.+F/3H%BBAFC;7/)60</+GH%!8&%#FC:>28%D
@r2542
TACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACAGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTANTTTTTTCATGACTTCCCTCTCTCCCAAATAAAAAGGCCTGCGATTACCAGCNGGCCTGTTATTAGCTCAGTAATGTAGANGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGC
+
+#$((")'!#)#)+)*#*$%'*+&#+(#$&#$#$###&*&($%)!+!%'*(""*#(*('''&%)&'+)!$"$')#)*'()!&'$!$'*%')+*$*)&"+"!%&"'"#'$!+"'(!'!*('(+'"+&*##)+&!)(*(*(+((!)"+)#(""!#&#&(*+&)!!*&!)&*#)%)&&+!+)&)&&"#"*)+$!)&"!&*%&##*#&%!'*&)((!))!$*#*'("(!
@r2543
NNNNNNCCNNCNNNNGCGNNNCTTCTANCCNNGANGNAGNACGTAANACATANTNAGCAANAGGNNNNNNACAN
+
#"$"!!!$!!"!$#$"!$"!#"##$!"!##"!#$"$#$#!#$##$#""$"!"""$##!$#""#$$"!"#$"#"$
@r2544
AAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTT
+
*(-?:631EF))F&+C%+=2G7$E:95*.27>3+:,4)G!C2=)1C9>:E;G1G>1AB(C*'8@!);B/"1?.1*==*;7C")%F@=2/41D*$-!8A(H
@r2545
CTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTANAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCA
+
%2<';4#?'+)*:3,4!F(H!?.?F073H5F856),G8/0%-0!$C>.518?:2E6'+21/>'7C4(C7&7E2)(C'2/EE-7@D@<E@4HH(*'?<0-:!22G4/@:-1!+&HED%?HGB42&,*8835ACB?=>1"$!7#
@r2546
CTGTTGAAAACAGCCACAAAGCCAGCCGGANTATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCA
+
<H54"$;2%8:#DF%7H(0);<@.)#DC4)F;+<!.$169<<"$=$C.-,F0&6#9;5'2+(!8GH)GH#?-6E*90;'?,-/D6C.>,E>!-(9'3=="4%
@r2547
TGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGTATCACGCATGACGGTGANCGCATCGGTGCTGTTANCAAGTTCATCAGCCAGTCCGGCATC
+
@.006B/..%:*"%ABA4?!#8%>".0H0-G2(%&%B>B<*&)=>)F8<6-B#%!%-$$/7F+=1&>9C3%4C3C+=*8/0*&!7*?(H8&*E%E?D">H302/&1+1)4D>1'%.
@r2548
NNNCACAACAATCAGCCGCCACGTCTGACTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCAC
+
!("*+(&"#)+!$+!#"+&"#%%+#"!+(+(!!!'*&$*%%$&"%*%&%##$*&**(%!&&&%)
@r2549
GTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTCATTT
+
?%-?E"#<;@17EB9*D'#@H"03%)<8)6@7527%=()'D:/'AH:<15*B=7'>/$@'5F;AC/D&?
@r2550
TCCCTCCGANCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAG
+
G""E7;;*?$9>!ECA://".-?378/FBG&:--"#5'*=E@).9("0E2-@"),3HE5&&=)&1'"4C%B<A2=8<,4E?%<'&81+!*>C.1,&(!>5=4@=F/D&1:0"6?C&!<&%<FA*$9.)9%:"2C><2<'>=;HC7%6>1251&;H=!#)#:?9*224?<918/"95
@r2551
GCTGATGGCATCGATCACACTCAGCAACTGCGTTGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGC
+
6D3892?A#+&<$9'.:2%A6$G35*F84C$<5+20)=;-(58-)08$F03"4#F)&"9(2FA=@E->00=D'@/0@DH!)1"*,G%G::&5(1#7E:0(B,-330?/5*75389H9B7,FD
@r2552
GCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAA
+
3G,*0>"5"/*6-G"7#@@0-#H&-),C&#)*<3*$2>>?);+3E22-;,'-*E#2?:&-D@0(*G<BD.47,:B60.=?H61G?=<0739(<7>:-7+!4""GH5<#:>88C.CE!D3.(3,5H6!$<@-;5-*32H'5F".2.
@r2553
CATGAAATTCTTCGTCTGTTTCTACTGGTACTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCT
+
!DAFD,06*-BE3:.>7%4-B,4?"F8/C03B4"#,#&!)"5-@@4E94#<56<,556;BH49@<%);H!*D5:4;7",!C;4(</8-((96(+C<>C@C72?G0-E?9E(E8AA3(A-%6%0@0>).G$(+!2$E:8ED*=#
@r2554
CGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTNCGGCACCTCAACTCCG
+
68.;<E<B)'E7*10$0"HD*:0&4=E-35=>$@/9E%)=2'>:E<"1>AA>=B7F!*
@r2555
TGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAA
+
>0!-,CG$B,845=82:?6@)*<-)-?/=G=C4.)55491->&2C86*GD&.BB!5A
@r2556
TGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCG
+
&C%$*'=@960$7/*A)4A3*F<&D@D1B=A49!@?9?CFBED<
@r2557
TGATGTGTTTTTCGCCGTGGAAAGCNCTGCCAGCGCCGTCAGTGTNGNATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTNTTCAGTGCGTCAG
+
&###!#!("$+')%&*$+%%&)'+)#+!+("$*+#("!%*'*'"*!!$!!(!!"###*(!(*!%$&$)&%*%(%(')+%!"%'&*+$(&)#'%)(+$'#!$#&'""!+"&$'#$$*"$$&%+&%#%&)("$#)"!)!*!#(%)$&&*%##*+
@r2558
ACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTGGGCCAGCATGATNCGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACANTACAAAGGAGGCACTCACCGCG
+
)*H1;/87<C/@65F(@*.#1095D!70'?>0.#B7&9&7A>0-':<;A35C1.,22H(CB?E!/G4/BFEGA.;7C$*'>:F.:)D-E535#'25<=/F3(9'A,?;&A<@D2&@A+,/5&8*A?:
@r2559
CGNATAGCCGGGGGCGAANNGANCGGNAGGNACAANGGNAACCCTCGCAACAGCGNCTGAAGGAACAGTATGGCGNTAATCCGCTGGCGCTGAATAACGTCTTGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAANTGGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGGGCAGAGAGCGCCACGGACAGTATGTCGCAGNTAAAAAGTGCAGCCACGCAGACCTGTNNT
+
()'(&*"*'$#"%"&(!&(!**"*&%#(")#&(')"(#!&&")&%'##+'#(#')&$*#*$%%)()*!'*()%#*++*+&*!%""+&$*"&#"&$&&%"*$'$*!)&)+!"%%($*%+*'&')'%&%(&(*(((*!$&*&&'&"*$&+*))$#')$)"+%!)#')*&%!##%*("$##'!'!(#)'*#$*)$*&*%"!$&"#')"#)))!$+!"'%"'%)"%&'%'#)+!*)+)!**!%'(&$*!*
@r2560
GCACNAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTA
+
GA?D&?B1AG<@(+<G-%1C<=50;)#,A;!G&"<-+(&/*E."(,
@r2561
ACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGC
+
+)'(*")+'!&"#+*))'&'')&%"*&#$+)(!##)%)&!#
@r2562
NAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGNTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAG
+
$G0.D%8.7(F04>"+#0"%G@<%;.!B+G$AA9?2F9;;45HA2CG#0/$9""'HC">&H.&F@="7.&)/1C5"<8$;#8H5+!8//G442H;=.C%.8<%H$:E&<E=.H!!G3">BE4(:3>!G1<H*A+>;=>*HH#&=:6)/)@-7)/=;8%83$5>*)G@5.0:5,2/122DE05@48DH:,<A-=3;D"D08>*!>4G3!:0,3>"H9(A.:9H#GG6="?H-@2A*%5-'/::">;0"
@r2563
NNNNAGNGTGANGTTANTNNGTATNANGNANGGNCNNGNNTGATCNNCNNTNNNGTTNNTCCCAACNCGNTAACAAANANCNGCNCNGNNNGNATGTGNCNNCNNNTGANANTGNCNTACTNNNNNNNNNGNNNACCTNANATTNACANCTNTNCTGNTNGNNNGGTNCANNCNANGNCNNTCNNNCNNNCNCAANNTTTNNNNAANGANNNNNNANNGNATNG
+
"#$!$"!$!"$##$$!!!!"$#"!#""!$"##""!""$!#$$$$!!"$""#$$#$$$$"$$"$!$$$"#"#$#"$!###!$"#$""!$!"#$!####$"#$!$!$!!""$""!$""#####!$$$$"$"!!#!$!$"$"$$""#""##!####!!"$$$#$!$#$!#!!#"!$!$"!!$!""!$!$!"#"#"$$$!"!"$!"$$""###"$$"!##!$!"!"$"
@r2564
CCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCC
+
'G,<$@(?G1%.69#..&D7#:=6@:&H6!$.7;)#'709<BA0B<H4-H/
@r2565
AACTCGCCATGTACTTTTCATCCCGNTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTGTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAAC
+
+,31<:1<#:&?@9D#)7(>=4&B%&#G,!755F8)+G-@>3+*"E!H>'G;8/F>)-/)<H=7).+?>B>93B*ADG!DC6A#H9)<=G.'+B;G(@7=A2>&"&),G2>#(<(89@<:.5?B;<A49.B9G*>4!7=11$*@/E$8+#$E1;1'BB=%A1*B'BGD8()C>#)B(2@*'5<F2@C7C20G49?DD
@r2566
CTCTCCTNTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAANGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCNAATAGCTCGATGCANGAGGAAGAAGATGATG
+
#))!)"+$*#!"!%*'#"'*&*'("!"&(+)%#!'&$""%$#'"*#'$&))')!!!&$'#&+""*#!')$"%!%!&&%(("(*'%')%$$%!#*&"*$#)'+"'**'(%''$)!'%*+*'*$!'#*'%*!'*"!)&(#$(#!!)#%"$"#&$&)"#*)"++"%*#+*+$)#&$%))&+!)$$**"%())#&")'!*")(++&)+!%#'*)$#$%%
@r2567
ATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATATGGTGAAGTCTGCNCGTGTCGGTTATTC
+
896B(B'G#(D,?*6&&G-%?9/"0?,A&1!@?*&F,C&#&F-:9)!%D:7&*!@8!:@941A%4#;/
@r2568
GNTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGT
+
"%+'+*&*#"&#)#*&***#"(+#')!#$$#))'!!&$+!%*#%$#$+#%#+)%"%$+#$$$#*(%++#$)&!!#*$$+#$($#!*)%($$&&$"""#&!'$"(#"*+
@r2569
TAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTANAACATTCCAGTA
+
!(&$+"%(('&"$"$+''($!)*&&(%$+'%!'#((!#$$#$)(%!)("*''&#!"'&&!%)++*((''!#***("!')'%$$*"!%
@r2570
CAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTNTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTG
+
?&G)A'+?,C';%H%06?>B,/%-(9:A/A'11H>!.G3"),$%H;8+D9A>>*-'#+=,!36"!**(,D8H3>>9G17,4?!C%G$,7=E028B
@r2571
CAAGTGGGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATA
+
5"+9B9//5/9D>"G1E964B52C<*'("+5D%263B,F(+*//10,#>AD#!!!?671;+F(&$7"G58;3'+FC<"/)2'7H;)F@"1(
@r2572
ATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGC
+
B!.+7(:5/+)'=(*,6.+:)5%#;'?DF69@H(/$53C)('"6(!"1#9;#'GA"$A@+;1=%31@5"B*=5D&ADB!E9-D&(==1%87&@E"
@r2573
NCCNAGNGGATACCNTTAATGCNTTCTGGCCAGGCCGCGCTCTGTCNTTTCGGCTGCCACACCNGCAGAGACACNAAACGCCGTTCCCGGCAGCACAAATGCCANAGTTAGCGGGCAACGAGTTGGNGATTTATGCGAAATGAAGTGGTCNGATATNGTAGATGGATATCTTTATGTCGAGCAAAGNAAAACAGGCGTAAAAATTGCCATC
+
("!#*('&"&*#&$$#**#+$(#(++(+'&))"(#)+%!($"$#"((#!&&$+!(%##&+%)*&+&"('+))'*(!('*+$'($()$)"+#"$!"$++&!"&++(%""*$$)%$(&#+**"$!)#$"+(!'$#&"*#!*$$$##(&)'&)&()'')(*"*"**(#)))'!'!'&!)&+"*""&('*)"'%**($)$#&*'++&)$*"&&)%
@r2574
CTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGNACTCGATGTGTTCCGTGGCTGGG
+
0@8H=5>A(G/$//%24$HB'.<;/0/7';D+2F2$4HE#.="$5%*;EC0:!$/"5D@%.'%+AG#%E0<0+>H"+7
@r2575
ACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCANAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCGCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGT
+
<?"?4??A=++55$HB.$G!(A2:=?',*:HG,1)%$?">D5>9H&DA0/G:H75H@7#)*<)5A#5&C(4)G)5%8"')->*'D(>><%28:*(=+5,&A'(.G"4;(;4D0,/+.),H7(=2B,A"40;@,:0#'&B3'"91855!<0,8:@-G@24&D(-C('CC"FD=H#6=7@"&5(F:A,G<G+,5"DG47>974+B"A+#<G#HD>6029/A?
@r2576
NGAAGTTAACACTTATNAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCNTCTTCAGAAGCCTGAA
+
"&2F,&'1&*3@:-F+7?(H0AB?"<5='54CE3)80>3-=?2"?>1%>,8F:/5075":"D"A/'G91'#<D=!!3=!(H+2+;*EH
@r2577
GCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGNATATNNTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATT
+
A('%E!GB)%E&;386FA=.G03-*.4*#F0=-.0<C$+)&',/%';H9FF9'$1!E$%D*<+BH!AEF,>:%?0F6#2@(0B4E"4"(',!67:5,F7H:3<2"$?A/)2%39!=762%BF:H77;F:).(&-H'D$"#>-#G3.";+;,(=/3&4E!7-E4'#,6G&8@E8,E#49"?2$7>5$G&+=::H*B4;';9:=<
@r2578
AACCCTCACCGTNGTTCGGNCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCC
+
&+#$&("()'%!$!(+%("(!('(!%%##''%$%&++*$+'#%+%%"!$(#)('*%+!!$$+*(#$!%$!&&$%+*")##"($+'($%(+(#*
@r2579
TNNANNTTCTCCTTGACGGCTTTGAAGGNACGGAACAGCGCCCAGCCTTTCGGATCGAACACG
+
*"(($"%+)"(""#'$!%%"+&%#*$$*'%(!*"&#%*#)+&%&("'*"*$($%'$%&%$*)&
@r2580
GAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAAC
+
G1D<>;;A)D(4"64:G;G<*6$5*!1D?-.=B/FH#'DA96?7"%=+19
@r2581
CCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACAT
+
4=?(98>&DH9AC@#F7G*H'?HHD#GH@"EEA613<;("1<
@r2582
GAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCAGTGAGCAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGANGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATCAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCG
+
+)#&"#+#("'($*&*+$+"#(*&$$)+#&*!%#*!#+&%&"$#$*(!!+*((+$$+%*''!+%!#$$#(*%+!#*!'%)(+++%!))%%*(+'"&&$'"&#"#))($"(("*$&#'*(##+%)(+%"+%#)#"#*()(%"'''&!$""!*&+&(%)%%((++#+$%&!'"")"$)$&&)+!'#"'%+%&$!#"&'#%!
@r2583
TTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTNAAATAT
+
G3/+%##(4!>,'%,+:5:$1>*20>?D*.#!&5/5='G)9/"7@B!?F8(A6=>?8FH4F070(354.?&G<9F5&6&"88-'"8+&01)B/-2+%$&7#6.3(2(
@r2584
ANATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCANTCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGA
+
%!')*"+)%&#"(!)("&*#+"*&()*)$$&$&()%))&$&"$$+"&)$+))$%")+&#*#&"%#+#+$+#(&&"*'#*%'*#$+#+)"")&$(+%"(+)""#$
@r2585
TTTTCTACTGCAGGAATATACCCNCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAACATAACCGCAATTTATTTGGCGGCAAGACAGGNTCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCNTCCTTTTGGATAACCCACAGTTATTCATGTTGCANGGTGCACTGTTTATACCAACGATNTAGTCTNTTAATGCATATATAGTATCGCNGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATANATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCNGCTCCTCGCTCATAAC
+
00>H.C5)#.?&C#/9"-$2H4.38E1:?$967C1#?,61G/+G/8F'0,;?A'9*5=+,#5$F;;D4=(8D(B-#)":9",(=,/(H#/3-&A:8<.6E#FF5@E9(F72'/D)>'A;B2C-.F;1H0D(<2</#2D6DB07(=1&'05>=H#3:5D,E+A<%?A$2,9H+G!75.1&FFC&A@&.0C:5)&-5-#97H7GE6+C+.F2+:>A1///%#2?'2$+0+$$:1/,-B7$&0<8G<??3#C&?3D"4H8)?3A(200?$CB<;1!;9<3<#E%+B7E=4"#$6D>C<F6",B*+')B#1HFHF4-6/&5EH<DH733>>;6;(.0=1?5%<.B3F@03',:/&*6<-F;?F4<9C&85GG+0(DC'@7,5>:AF/9*,1$3$D1*@0,"'%9.'=%D'D$@/+228A?G/.7.
@r2586
NTACTCNAGGCTGNCAGCAAGCGCAGCATATCGCGCTGTNACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACG
+
$&#"*($'&(#'%#(#+!"'#*&))%+$$$+%$''()')")!+')()"$'+%)(+)''+(#')$+(#'''$*'%#"#('+%'$&&%##)*(+#*&*+()%#+*!
@r2587
CTGCATCCACNCTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATAGTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCA
+
=<6A1/G.4B#)"<2?5>,7C0#G$95571>08!/"+8@6E+=.G;"D>;)&7<-"2:E46G1=.=05=<E!B,C.&B(D(!'F9=4;86'!HG?$D1>;>F3$.H@$-AG!CF%)=5()$D&:1?H00/@*9FFD,+8H'6.4(+'"CE$5-:'42H+%(:.)C'=8C"+'(4/2$C2
@r2588
GACGNCGNNTNGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCACCAGCGCCAGTTGCGTGAAGCGGT
+
$#'%*&%&#)#*+%'#"*(($%+"+%#&*)*!+&%%#)"#)')&(%%(')#!%$+"#('!(&#")'(*$%#%*!(%%"$!('"+)
@r2589
CANCNCCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCA
+
%!)(!+)))"$*('%*++#(+%$"""+'#"''$+)&'(+!'($!+(#*"#(++$!!!'!'"
@r2590
CTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATT
+
43*,G=*:;$7G!#(@*+E<4:-'7:=2:%--:*1B,$$H&>$=C)F1,',94*
@r2591
AATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAG
+
C*/,G%+81'=*31$?C:/8?)!:E8)<+,!F9'41=-B/&3-,;=E>$&>,=EG/9C.'8:
@r2592
AATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAANATTAAAGCAATAA
+
;),<H<G>D*'=D)-%5!=!FFGB*D!'<A3;/5$1G3*!:=2A:<23G;02&B46#G""@F99+0?%&CA$4?E(7"0=A!=@567H$;@74/46E2>:5/H;"#-H=
@r2593
AAGAGATGGCATATTGCTACGCAAGAATGAAAAGTNATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATNATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCT
+
-(0E@F;9CAFBD$+E(?BD6;95?9.6.#;:89%:&*+7-@5G=B1<?G/,&4;#>&!A#-;A(>*4-9>+"'E)<!(583<%19$,<A7'5?3+00<!C2!.-#,F9C"HF@F331/<-0)'+,3&4&75,'%*H37(&?;$&E,BH5%9,C@B4#10D8!3"**<,
@r2594
TTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAA
+
@2;C%3:6*5>$%B?7#4(C;++;>:1@F57'EB3+&9'6'>9$+<C4$(,H7G%/?;##*DB"8HF6H#"F:6)5@B6+;1-"!2#
@r2595
AATATGGCACTCCATACGTCGGCGNCGCGTTCTGCACTGACAGATTAAGACTCGTNCCCTTCACCAAATTCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGANC
+
073@4D-'#$(&4<./!9:?*@!B/7=HG-9:6)C5.3,;#;&&"->2HG&G/:'/<=,2(0.:?>8C)E"&(:A#94<2A$E3#EHF&42/A6<)(4?H$#-=G(;(&*:-,,:(7'<G'))!
@r2596
TATCGAGTCAAGAATCCCAAAGNGATATTTTCGATCGCTTGTTTNAGTTTCGNTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTAT
+
FC;%?:C;<3(#(FB$-!&#=&34&<4/G<HA,9'@$7491/=>)D>$'?2@#B!.&2!CA>EC:*6';"<#>=BD"3&,2'>F*#+"8(0!031=CG5:F1GB$G(%C9$+-@-D:*(8!;3-
@r2597
CTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCTTCTGCNGCACTTTTGCTCTGCGATGCTGATACCGCACTTCC
+
5.B(5;*<A.07<H%-C:$=G7;0%7"/G<8.,E0;C&:4E.B0$&D$9.9?'C6)G,*&$<75C8@1,=EAHFB8:++9&.9
@r2598
GCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTTACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTA
+
)A+.H2@@@G+)+$==,1H,#H;>D;7-707EA(17D18BH7;=E&/8'19(.2?2!4A!A!@B>11D*9*HC@8.B'6-.+$:-'
@r2599
GTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTNATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCG
+
5<2+>D?2+E3?B9<.A0;'9"=.''5)#@%B8C4<(#=H97&172F-DF!;/*4G8D5!DD6/))8H4="(--2#F4;16.A0)C>D0B0'EA3(=<(>>!0F<:1#;A<)@B,*674
@r2600
NGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGNTAACGCTGATGGGATTCACACCGACTCATTTAANCCTGGCA
+
$("&+%%#))$"%)()"+$!*&'!*!!$$"$+!&)$'"!%""""+)"+&(*"')%('++!&&$*)'&$"*'(+)##*!***%!+"*))'!"#"*%!'+(!&#'#(+*&)$)
@r2601
ANNANACNNANANAACNGCNNNNCANNNTCNNGNGNCGCGCNNNGNNAGCGAGGGCTNNANTNNNNCN
+
#!"!#"$$$$$$!##$$$$!$!!#"""!""$!""#!##$##""$!$"$"#"#!#"!#!$!"$#!""$#
@r2602
GCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAG
+
H(,D/!;)+8*1-G+3$9$AE<-,.?@+C4(?;2("(@"!GAC=$C%5
@r2603
NTTCACGANTTCACGNNANNNTNCNAGNNCANNTGNGNNGCNNNCAAANCCNTANNCNGNNCCGNNNTNANNGNCCNCTANNCCCTNNATNANTNNGNTCNAGNGNNANATNNCNNNGTNCCCGGTCNNGCTNGTNCNTGCCANCCNCCTNNCGGAANNNNTCNANNNGGCTGNNNCNNNACNNGNAGGCGNCGTTNCNANGACNTCNGNNGAANGNNANCTNTANNNNNNNCCAGTCGAGATAGCNCGNCCTCGNNNNNTNNGNNANATNGNNACNCNCTCTNGCTNCNCCNCNGNNGNNTCANTNCNNCGNGNCANNGG
+
!#!$!!#""#"$$#"!""!$$!"$!##!!$"#$##""!#"""!$#$#$!"$"$!!!#!#"$"$!""#$#"##"#!$!"#"!#$$""!"!$$#!$!##$##"#"#$!"#$$!""#$$!$$""$#""!#"#!"#!#$!!"$$$#!#"##$$$$"$#"!$""""""#!$$!####"!!"$""!!#!$!!!#$$!!!#$#!!!###$"!$!!!#""!#$$#""!$"##$!""!!#"##$#!"$$##$$$!#$#"#$#$!!!"!!$!!#$!$$###!###$#$"$##!#"$"!$!"$##""!!"!##!!$$"##$!!""$!#!#$"
@r2604
AGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGANTGACGCGACAGGAAGA
+
GC4.-8/>1@-;H6E1F+!+09D-:..*3A:F&/-"%&"-&(B01(A?(7B.(AHA"."H1/#G,G!5"+0;;+007C)HAG%>BBG!:H9@:68>B
@r2605
CCGNANTGNNTNTTATCTGNCTGTCTCTTNACACAAACATTGCTGATACCGTTTAGCTGAAACGACATAC
+
"&%#"#))#$("('$'*)"%&'#*%)%('!+$*!"'+$$**+%)#*$'#(&!$+)!%+*'!!)$$*($!)
@r2606
CCTCTGAACAAGGTNANCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCNTACGTTATCGTAAGC
+
4(/9#)HE&96C.8DG?70/18;-*/BF7(!//5:454-BC:'DA$!>3<,/D&.A'H7:'.!-C@!8/2'->H88$%/;!>4+""F@+8+@B2H!($)!@'B%C.BCA'4/4%%='235?D1(F7-.#06GH><;"(501:>1D+1@H+0;10$:2C95<.@*6F;":AF<C!6@/3G;";2<?"F2C/2+
@r2607
GATGACNGGNGGCGTAACGGCCAGAATCTCTATCTGGANAATCTTGAGGCCACGGGGCTGTATCACGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCA
+
'$#&''&)$!$+*'&)+((+#!&("*%"#$+%%*!%"%$'(+(*()($')#$%!#&!"("(#)('*"&$)%($&%&&**$!*&#+!!()$*)%&)((#&*""#%)$(%#!!("#)*$!$$
@r2608
CGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCNTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGA
+
B.A-E!4F?C0;9#E%7.(A;()147&.C@"/5B7=09D%/="2;%E372#4F.&#9E*$,E4=;E-=(5CA>F)6'@+(7:>@'('9$1>/+>:E0@03;%,;4"*?%H(
@r2609
CCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATT
+
960)>#+%G/9.5:3+"1G(%/=G2,$+&G.2>4/+E,+)17)925E2@9A
@r2610
AATGNTAGAAANANTTTCATTACTCACTTCCCCACTTTTTNGCAGAAAGAACAACAATATAGAATATTCAGCTCGACAGGTCACTTATTTACCNACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGCTGGTA
+
(#$()&("&#(#'*')'(&+%)$)#&&+')'%$#%('(+*&!#(*%!$!*+'"!#"!((%!%'"&*")((&!'%+#!(&%#%)""$+%%"($%+#(+!+)+"&+($"+#)!+#$!*()+)#$$#'*&%(*(!$"#'&('
@r2611
CGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGA
+
A/.(E4$*!(+(!#E:;E6"<-<';.125E5:!A)$*:(A*0"
@r2612
GNCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCNGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTNGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCNTAACAGTGCGTGACCAGGTGGGTTGGGTAGGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCNCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATNTTGCGAGCACTTGCAGTTCCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCNCCGATACCTTGTGTGCA
+
52,=2&G5-1$&)B(D==*7B1:/*91!*1=%#>2G<*95(5AE!-83+9C2645,&H9;FB.542FD#+3D88;>$*%1@49B=BCA;/$5G*8D&,">EA,3*@1*2CCH168>'@DA=G'!=5H:=$&.0)E66@)*F&.5(5;<!&CH""DF+85!G&$?%AB..D<."EC"H'2+:>9-"<0H)8+*H3C-%-<3*(7(D=9:649$=(<!C+!1(>"<%B!";/,;685%.1E?F7B3@!BE-7D&<8,H-;:--$3:#F117:!%,A%:*$%(84"D4#F(G<6&!$A(+F>A8!!8D!.;/?/:!B'=,6;(67/2.(G,.)5A*D5<(A8?$"5(?,H:-HBD1,$"@;B>A%/((,,%=@=9@4B&&8E=A+&95+>@&2/5E<!)0,;@:+1C9%,1.">"3#A7)5%)#5-900#(2*H%&2:8#&!>4#2.!-4*&/C.;18"-""95A:49+;
@r2613
AAAATATCCGGGTNATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCNGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTA
+
7"0$B*"?23H!3<<HE*1C&4+'<1B68?.5*?'AA)$E5@!*"6!27;&@G<HC7(4F68%@A,5)'C,1"<F;F'A#8>1@D94<F=B42G>7C4/2GB#-7:.<;ECF+'1*;EG4/%9!<=B@F=12#BH8E<G9>5#%5,!=!#!+5*(+8C<=C=H,#>'&D@<3'EE4?45',";(8&9%=-@,</?;57)7/6@/C3/="GA.$%?2BB-G;#;'B98E.3A07#'2?B?@?6?!A::CF7H5827.511)+
@r2614
CGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTNTGTGGCGCAGGGCANCCAGATA
+
=FB4)/E")(C=5/0327#D,*EE::E0015'4B8*4<D&,.8HA4C&"66:>D)F0(&<9,!AFEE=%
@r2615
TTCAGGAATCCAAGAGCTTTTACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGNAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGG
+
'&#&%+"++'(*($)#*)(')%"$$'&%'+*!+#!**(*"!$'%&"&$!(!%!+("++)(()*#$#*$"!#+%$&%$!"&"()'!)%+)$")*)!"'#'%*&#"(%!&)$*"($!(%!(+
@r2616
CTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTATATCCG
+
+#B2(B1"2F%:08!!6,0"!'@"41#=9;(!(,<6:=B801AC&G@>A
@r2617
CGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCATTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAG
+
A77,A7B<E0":-.%B,1C4#-E..,;G;C,6'5//82()0&.:-)#/AEH&.:$0H;&5!1,;+D'0A771776D%A$.E5<#05$,3!-;#$*E?F!A'D&*#5E+.G"F232<#8D)4B/BB"9(,,=6D8>A$4A<5;(%DF3(?1$1.=6GD$FG*+&$%@@G#F,+,*'/%1/-;0&G
@r2618
ACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCCGCAGCTCCTTGCCGAGATGGGATTCGG
+
?*05$"D1(G:09H3*8!#E.)#9FD&747-C42##$;$#51@F!)6F6(&F-E$5-8!C%GH;@A4&1F62F.%C!A2)2";,H)4E$7+96EC:B44@H'ED/<9/2@C,9?:,8;H1>3!931&@'=#:-H><#+'.?4-D";H(E+HB/-7=";H
@r2619
TTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCA
+
$D1G#C7155!2;2&*64'8F#.?#0DF5G9E?2/86'67:1-%C&+(B+4"%
@r2620
NTNNGCNAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAA
+
'%$##%#(&+!!+'!+"#&#'+''+$$'&)&&')'$$%'*#$%$++)&!#(#($"!(%'**%(
@r2621
CGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCNTGCATTT
+
5&5G0<&@##ABC?=6CE=C)G=6.H+.#;79G6:4@+3?H4908)
@r2622
CTCGATATGGACACGCCCGGCGGGANGGTGGCNGGGGCATTTGACTGCGCTGACATCATCGCCCGTG
+
#"+"'#%+!'+%%*%)!(!**+'%(*$!+$$'$')"**'+("(#&#!+#+$"#'$$&)%+$'%$*""
@r2623
TGATTAGNAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTANTATCGTGCTTCACCANCGCTGC
+
+*$#&#*)$&*+(+(%+''+%!$&&!))+'%"*#*#%+"&!"$%$&)$$%#$%#&(*)"!'#+"()"$&#'$&+*&
@r2624
TGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACNCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTANCTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGTTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGT
+
H5/>*><#A"8@:H*(%F':'-+C8D%"%0$69$*7C.<B<,B2*H"6#!H27>+*/@A>6/4#.D.D<9?G=B2(=F:/G?!(#@"1)59F1CD-"BE8*F'-(A//(*A&*(4$,3(GB:B7/:,+=85+6&6);?'A9@#AG6H:.9&HDC#,;$B7B:*B<HH26A7D-/5:4
@r2625
GCTTACTTCCGCGAAACGTCAGCGGAAGNACCACTATCTGGCGATCGAAAGGATGGTCATCGGTCACGGTGA
+
&AA0;A0&B@7,A:1(!==(?+.'13;-3F8,6+<4>2&"%2AEF1-4E?3/FCFEE7@F""?:0&B&/?72
@r2626
NGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTT
+
)C88GF4&&+B<B(;6>;0A<E'-.%B54:$G=FD9D3"/'#1
@r2627
NGGANACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATNTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGNAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTNAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCNTCCAGACCCAACCAAACCAATCGNAGTAACCATTCA
+
%"?3'93G<7')##1%%B6/#43=>H<$!?E/82"!?A4+,F/%?0='A)&E3E>,(1C?G*?#A=<@G6@&,3A+?1C?B/+'(/=D?E2$>)A=%>?E=#E"1CD2/,86,A6B0,&%3(BB4('$2B=(1AH$DE="C/<G0A.B;BH$49;F8<5H.%3*<=F2<4>BA4:(&-#9"GC"7.72)'>G1-1A<.*?!-G72).9.::C7#H.F#*(>)
@r2628
CGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAG
+
9<(&=F":./-)>H,G%"07:F7G;$:A#+C'<+8;?%G3!A73?+4!2=;*(8>B3"H<G)2*@D40D?11;084)7E@;;E".)3CAG&39B?(/<?99&'A6,
@r2629
GGGANTCNCCTGTNNNTTAGCTTTGGTGGTGTGTGGCAGTT
+
"$)#"%'!)#*))!$##+"$$!&#"(((#$+($#&$"#(&)
@r2630
CCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCG
+
"-1')%7922G-(3@A:++6719!CF/)<D,>44;83<:(::-0
@r2631
AAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCCGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAAC
+
>7>?#?47@(<D=C@:,+9;=<4B#;60@!D=1A@5=-!AC<(>&='><&(E3@E"?@G3&7"D@'7#3G9*74DG>0-@)3BC;75D&E0&"EC*.#@14&<031*C)=6DB"($A#BD2#)?'?E?*;-)B?=*1>D)(0178)/@B.,E(1E:2=2&9!+@A51<
@r2632
TCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATTTGTTCCACGA
+
1-)F)3=H,7'6+;;".!$9+!H>(%7-&&,#627310>G%73+3<AB@E94?1?22/@H,4?@:3>24.><"-4@;GH'1/=47")!=(;,,
@r2633
TGNGATNCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCA
+
))&$!%+"&")')))""(!)"&##)!)(($(!%%)&%*!$#
@r2634
NNTNCCCNCCNCAANTNNTNTGNCNATAGNNNAANGGNNCNNTCNCNNTTATGNGNNNGNCNNC
+
#!$"##$!$#"#$$$##"!!$$$!""""""$!"$!#!!$$"""$"""#"#"$$!!!!##$$!!"
@r2635
CATCACCATCCGTCGGCAANCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAG
+
7$/G-B$(<'#(50)HG#*-2=4A!)$'?;.?%:-$4B993#34G.9%(@&(7F$%
@r2636
ACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGC
+
6=(#6E$,@B-";?0#F":*#=F7"0/%0,3%A"@!2A50
@r2637
GCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGNAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCG
+
82C21B?D792>.B,%2#'F;2G@%'=,?HC-=:.F)*)3B:G6&$<7-'!GH./:/*!>8@H/A?45>A.=7(/(-=4%!;GD,.E83'4"-,;0':H58E'>+$;:/3F;&970CF=,#)D+H#40H$2F(%,)F,4."09($.5":7);(C.:#;+"FE-"($6(1-$7,5?=A<
@r2638
CTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTNCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGG
+
22HG$=CG0!$.-E6<!)%8&3:$*>)"7;1781.E%1C8DC2F;D6(<;2=.%(8)B>)(G)+>3"0:=9##<':-99.E>1A6..6,4##?;*E70"7!#EH)E%3=E=B3$>+B8(8),"=H=$0;H"&)A35)1(#G=A>>)F@%:2#
@r2639
TGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGNACAATACCAGGACTATCCGTATGACTACGACTATTG
+
3'<'=/B,0;*..;/0/6#/H>F=G!)E?94$8><EE<5&=.=5E66<G3*8G<-"BBC;)&BHF5>$6H$EG4F;(7(@/<E;3?9D,$('*58'9:H<+%83031!-%42&8B05<,7<%ACG%"!#7>97**&6
@r2640
TGANGTTNNGTATNNCNGCNNGGCCTTCACTTCNGCATNNGNACGTTCGCC
+
*&)!"#&!##&$#$(("'%#"!#&$)#()#$(('%'&)!')!+)&"&%)!%
@r2641
TGNCACAATCAAAGTAAACCGGGGGGATTTGCCCGTAATCAAGCTGGNTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGTTTGTGGTGGGTAACCGTC
+
'&!'"#+%)%)((&%!!!%"&*"+()!*$$""(&%*#+""+&$')!$"#!)&+$!!&$"&*#(+$(+&$&%((!&+*#!)#*)"(!$&+**%%&!()'*%("%)''!"+!(#(()*+(*#(*!*%*)%'"+"'**)*+#*("%$$'
@r2642
NAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTC
+
%.-E8FG2<*E9=<1*;(!1B3$:,2GF":02=;7%42H3:FG&H6,DBB;7%,5
@r2643
TTAATGGCATCAATGCATTAAANGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTAAAGAATTTAGCCCTTCAATCGCCANAGAAATCTACNAGATGTATGAAGCGGTTCGTATGCAGCCGTCACTTAGAAGTGAGTATNAGTACCCTGTTTTTTCTNATGTTCAGGCAGGGATGTTCT
+
E(6!&6=C0</EED7"556,8E9*#8D:C,D1'6.'5"<$*9A!5)0#*..((/0&6"=$/9&?1.HD&8)C@AFA"2/D1/FF2E(,HG@6"5-1E02;>1GD"#"!+CG;)7:0-8:3#&837+"C"(>F7!@(>6A1"4<7&0+=E/AH"F-)'*;!#:-;"7%3@E/A8>8:5A>:B-3B017>6=$,
@r2644
GAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTNCTCTTGATTT
+
+*+*'*+)"!&+()&#&$')*!)++)(&*&&*)"*#('')))('#)%$&++%"&(%$('*
@r2645
AAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTANTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACNCGGAGCAATGTCGCTCGTAAC
+
%;;5GDCE),29;!".B=;:CE;/,@7H6=1<'!8E2-34D?DE'#"*48,1#'0'%/1;B('&%$7C3:@?5.D;G5FD!F',@2EC?))B2?D0<."#DH'?!64AG>.$H=A"6-+0+EHGGG26#0)?2"!HH!.-,@D.A?3"*.G6$/##'<#%-'-6F3<A0C";+$+
@r2646
ACACGCTGACCATCGGTGANGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGT
+
##4>;.9,/1,E2.?:.0A:#G5"8$$(88EED!@-?.?*B1GA.=G5.4E:F:1$8?G(16<G+3;F1'.$4"G-'8F8;)*<6CH!&29<=@=D<0;D4=??)*/2,F
@r2647
GATAATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATNTCAAAGCGCGATCNACAAGGCCATTCATGCAGACCGAAA
+
0H'(%)F3>+E?#&.),%8)G=&0$9,#$?)*<!4%E&+;+D>>'3::!#@&?@;%GH!*5-(;,1)C=/,**.-;B<9F<?;"GCC!1B8B
@r2648
TCTGNTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCG
+
,(0'*8-B4*-6EAD8G8$3!.1,4%H=@F*?%>'+AE1=E%G/D@:6
@r2649
AATCCCCAGTCGNCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCNGAGAGTT
+
0D8-2.D*>'!9B<$5DG1*):9A"<C9.G4#)19'>H;)%?5!(03"8;8;('>,
@r2650
CCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGC
+
#D@EGFC0,4&-@G=>"(*"."/)$FFH0!*H/%%;7A,C(9(D,</E655#6?E0?D(5A>5C)-.31DB:1E-,'6-7
@r2651
GCCTGCATAACGNCNNNGGGGTTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGAAAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAA
+
)#'*%!"*&('#&#!%)$)'&'%""*&+*)*!#*#%%&$!&+'%)%(&)"#&'**++##(!&"(*(&)$'$+$'!'%(*!#)"$%%*$*&+*+!$$"'#")(&&%)'#"+%&)"#
@r2652
NCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTT
+
!6+6.52B%*37'&B;DG"#C&!>BF&$%A,5*:C0011F408(+)5DC88-/83G/,>"A,%:D.F*/F6!-;F&=;=(F2B(>%2./
@r2653
TGGAGTTNAAAGATGCCGATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGNGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGNTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCG
+
,/48<;/$!?=B4H"'1"F@E'<D:D3%-'E>2C?;F33@1F<8B#7@)0G$358E%4;2E@:9:,C7A"0#=B?0=6")HA#;.4+9+#FH$+%=H'1+>-="F/+3$=%&AE(2.E&.H1*D3C46HB5D7$?)0#;%2-"(<E!&'H0!$/5*5E+"";"$6B0H)B!G(#1F44H2:C$>D6DE2)>)#*:2-17A'-)G993=.D/3@HA%0#C=#+H)7$?A@EG7'/&&6:A>?G(61/D"02EG3;>8&5!%$;-/)-@!+&8G*116>9)6$?D<1*;G+G?A*/4<C.*:-#)(?@"*#!==?CF!83G<7
@r2654
GTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGNGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCG
+
'1;08,=/9A3;.$?7"E86C#H1;>21&>9H*H>A3")!>62'#&7:!42?5C:@17!:'G;)A/71C,E%$H-<2$)1GFFDDH.+(>(BF%1729';"&$-7HB%30H!7F0?&FA<<!,2C+8D:'!+!3/8C!)2E1%$85&6*,(@3EHH2G+4$!/3E/900-3CA23?!91:B938;,*72D?7=<4=253B$25G18=1
@r2655
TTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGNTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTNTACCTCTTCCGCATA
+
7/&#/H%,.A!2=:8.*627#&&HC;;G(1)>1D:,66(=D:E#74@)06<$:!'A<=H>?491>1A-H2.;"<''(/8+*B<?7$<68CE(3?@$:4>E1#D?.C5AA-5;0$&2BEGG=0"=+:&@#;>-)=2"C.,B"((50/1H+0"GAF0=;
@r2656
GTTTAGTGTTATTGAAAGAGGNGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATG
+
+)/*1";%*2(85+(1:</*F$<>;FE5ED3#B-@5BH,;,45>D1-':"02,@07916F;:08A*(.<%3.-%?.&63"
@r2657
TCTAAGGAAATACTTACATACGGTTCGTGCAANCAAACGCAACGAGGCTCTANGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAA
+
:'*$79CE7),;5A5G01*%05)4;2)2@#0)/HG."2..-2:1D7:*6F*&3-2(0$+;G"G'G8FH790/!)F?)*1&H/#3=?+-@(079G-GF2E$G*.&7*#-!:+H
@r2658
AATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCNGCCTCNTTCAATANCACTAAACTCCAACATATAGTAACCCTTAATNTTATTAAAATAACCGCANTNTATTTGGCGNCAACACAGGATCTCTCTTTTAAGTTA
+
69C=E44=&(>"8'),+:"587!!+>A4&BA2:&#G%?6)3B'(688%B'@D!<6E(:;F&!HF6:.$>%&5=A7;9&%B"='&1+/:/%>5D@C)C&?$9>G(3*';??&2D"@.4#$9F7$>&30@>:G@F73)4,+-$,6<%F*3<D2!:*7'=C=@75H:3B
@r2659
TATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTT
+
H@)5'+)=1!D"6%(('&0B/'8"D%?8E99A:FH-A+G0H@G/B.A!%9<=2(2!+(,$;:H@.F$G?>D'!;.?80,
@r2660
TGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTAGGCCTGCNATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTAT
+
90!G>&5,.G7%#>!"*9EEH8G'DD#GE*):9.?,&G7E=3@!D<H$4@FFH8*@76G30D+4CA4?'F*B%18.BDB'E)3+0!3"?F!)0C7E?+EG4&70.B=)?1$+C(?!*-%5/8%%2?%G*@D%$3;266>,2)8DD3440(@/0;D,3<"=$F?6
@r2661
GAAGAGTCGGCGAACCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTNTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTT
+
.5=-<$/(8C*8-E'</%D0E*9"A14AD$*3$5D,?G.%GC!A9.@!E-E38-:$&/0<4=,C<-5D'H%(GA"-"AE:<@C*C(G#E@.;D/#*85;7=52=&0*70>94C55,<(HCD+H?2E(!4E#>BHB54D*<;507EA71&&A88C:*88$GB8"A0$;?AF,/1EHE)G5*,%0G';&3<CC03,..8H!%F8@@C;CG;:>GF*H'D<3+,>H>5DD9DD+.79/7;3F3(2GF%*01H/%*<=1&0%32D=7%'"23+,>D%#4@',+%%=-1B.@5!+31&*C22!=-;"E/77'HA35?4>-"?0<>'.1+$#!,B':8*7+">3'$:6<(0>#8$7&(
@r2662
ANCCATGTNGANTCTNCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGANCGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAAT
+
'')%)&"'!&$(%#''+"%)%+(*#)(*+&)*$!$)*#%++#%!'"'&*)!&#&((!)'#')+)+$)&#*#%+#'*%&#'('+$$&)!!$#&"!%)$)*'#)
@r2663
TGAAGAGCAAGCGCATGGAGCGGCAAAATGAATAAAGAACAATCTGCTNATGATCCCTCCGTGGATCTGATTCGTGT
+
86G)G@&!C+*#H,=1;+-.=<0@>1:D8&.:)2=34(9A7;%478#)E*6:+69)-90!A%+4DF+C2A";B33*7
@r2664
TCATTNTGGNGNCTAGACAAATCTTTCCACGCTNAATCATAACGTCAGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGT
+
%#$$(!!%&!""+&!%'!&&$##((+*#'+)*)%')+$#)#'&$&)%(+&+&%'&+'&&!%++"+"$%(!"%#(&#(%&'!&&(%&&$&$%+#
@r2665
CGTGGTGACGTTACCTNCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAANGCGGTGACGACTA
+
DD8:=E40.;.A424D$=>F2A*==+G::;DH#1>312#AA<$H510&FD@"@@A>93,)'/8*;HHD9GA?*@!/.C)(=?!"D&*B=8,3=,8@G(C9,40C"G-%<D3@(;65F2A0#+&$E$7@G.H"3$6+0/6?#C'(7&279$=6>:921F&/4'5"02-G<GA4GF&GB;>$8EE*G>-58
@r2666
NAACNGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGNCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGG
+
!&('+(&"*$")'*&+!(%!++!$#$&!*%'*%''$!$!*(('")$'%'!)+#&$&!*%+*)!#$&+!&%%(')&$%%"""+*"%!*+&#**!+*+(+%)))!*'&&"%(&""+((*"+"#'%#"%+)%(%"$*&+*%'*!%'"*%$(('*+)*'!)'
@r2667
TTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTANATGGATTGCTCGGTTTT
+
>?.:81'D4A2'7.!#DA@!G8C41#:/$;>!8>4-2-9(EGGFH)&E%(9*&*2'>0;HG1F0C.D5+?
@r2668
AGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGAC
+
B2,+8G+5<!$C=;E(?-C>11)1=,2D*/H3:3A2GDD$BB&>2@/0::6?:'8.=DF=8
@r2669
GACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGC
+
7F)?563EC+D0,4H4A7;(6/:+=:EB2::?-"E84BH$G=F??*#-1?-
@r2670
CATCCGNTTTCCTAACCAAATGATTGAACAAATTAANATCGCTCTTGAGCAAAAAGGGTNCGGGAATTTCTCAGCCTGGGTCATTCAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAA
+
(11%H:*!E+3/?F78:/::C;:306(2HG)CD#(,9.<C:)C+DA$"$8;>14&'4)G#21C61A"/D>@B,500"G=)"F2>1;/78%9*/7:8!*,H,'C7,/)>%'5-.>C1BHD$";-@9'$B+'+:++A8=#?,>0"A2/7$=,3
@r2671
CANGNNNGACGNCNNANNNNNNANNNAANTGNANNGTNATTNGCNCTGTTTTCNNNNTNAACNGCNNNGTT
+
$""#""$!$$"!$""!!""$""#!""$$!$$##"$#$#$##"#"!!##$##"$!"!!$!#!$##"!!!"$$
@r2672
NNAGNAGGAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGAT
+
%"$)&!$+)%""$)$+)#!$"+%$!++$!)(#*$#%)('(#'%*(&&'%&"'$)''#!)+*#)''%&!''#%)$&*()%+(+#"#!!*)!%''"($$
@r2673
ATGCCNACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGGACTCATTCGTTTTATACCTCT
+
@D&%9$.'<B>(:&!20B#,(';'?B'1C06C3CD+"F&;%354"<E)=<G086+79F*827<#-A(-
@r2674
AAAACNNNGACGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAAC
+
)*'&'*"!(&#'%)+)('%)''")!%&'$%!'%("*$$(#!&%)+($%)###&#+
@r2675
CATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCC
+
91F,%<:#++5<<+4BB%3-<;9-66F:+;12>1!DA=1:(:B(=?D+B793.>#%F0)H7#D)A%*G:;-*)9.G6'3F%>!?9>587H55
@r2676
GGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTG
+
>='HH("5@*0'!?@H"?)BH,B82:G%C!A5AG8=+(CBG=9B/D?.,&79;A
@r2677
CTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGAC
+
$2,F&C*%@>&C0@'C7##-?/!:>A5)*A36!,'D%+,A&E3>)BC9&D!?G5B2
@r2678
CGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCTCCGCCTC
+
>G3D>-FC/1)E>!8<*9=.3.<@3$B64>"E>$#<85*%#+#D=H>'$,H/3,BFG&36,'7E:F6C,;,E#/"+D<>%97/.+:F>,<+@#.,"(59,9/@!*6%/,;
@r2679
TTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGTCAGAC
+
6D#6E0D9$;'F0</H-#%0$HFE)D"'9'=?H8,87C"!2(;'-%@C/C4;2.02>4A6(B=,#6G)85@.&9$0A-F(*859-!G85.'B(F5@"@D,=2%/DCF05B49A(;:*CF099G6GA8)2:CCGC22B595CC$12G1;!F
@r2680
AAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACA
+
4"F)E0=@'3<'D*G,;-D(@;#?1@G1.>D.".B%@-E1,2HF%(63$*3',#-8!GGC3/F#C1*F'8*0(+$6@%*<+4=;=*FG'/,+B4H468(105-B/B.G%%=
@r2681
GTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGA
+
0%$B#2H+(#%&F4G=#0.;6:$FB5?%07H/E&:&BE7.*6.7'3=A460D4F"-H&E-"=*0/EB?0@F
@r2682
CGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGNTCAGACGGAGCAGGAAACTNACGCCCTTCACCACCTTCGGTGTGTCCCATCGNGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGANCTCGCGGGTTTTCGCTATTTATGA
+
;C3$A0;"8(&&638(%@:F+/./D!&+F.436+>'$)*&2BAB/ABFH2>%A0HB7:)0A<BF,=.!@F4,->"(0F+)-52<$E@BA;(E@FE>4A'B;/D78;5F$)"G<3F'%"G@H2)?G7HC!!!1*:<6?75@"A2?1D9EH<(B'+8F;G)/B-'CA?4E,!DB:5*
@r2683
TCAACAGAAGATGCTTNGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAA
+
@)?<3%4?4(:%)/C44(6!"'4,;9'#,8%;+G?+>D/2H?@>4="2#)D329:;9$1.H8'3,CBF5".E>3+=784G1<DGE):4C4@/F
@r2684
GCCGTAATTTGNGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATGGATCCCGGTAC
+
&*('*)%$)")'#++"(#'%)')$))"))%'"+!)"(+&"))$"+$''#)&(*!(!&%$&
@r2685
CGTATTNTGNGGNCTNNGCGGCTGCGNCACTTNTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCG
+
)((('("('#%#*$#'$**+''!+!($*#+%)*%&(&$!*(+')$)##+#*)!%(%!*+&*&*)#&#%($!&))!$+"(''!"()(('(&!+(+"$&!"("%#+##''+)")+##$")'$+((((&*#*#
@r2686
TGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACNGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGAT
+
C5)C#@@/)B;'=C0-E2$C295.)9)+773GG?5B@#$H/"'9(H=*9=B9)EF)>-4/D*2C,+EBE-C*"'2FDH2<)@B:F5""<G14@A-4B#+2.:?0E?+D3&,;<C?5A+:GG
@r2687
CATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCGAAATAAAATCATTATTTGATTTCAGTTTTGTCCNACTCCCTGCCTCTGTCATCACGANA
+
6C$%,!@,)>+.7:3H=A>:0A0;.H'E.B79>1"=*(.4(B7E0$28&4>1E')!4D'CEH4!'AE@.%9H5<5>+7=5F=2)02/13'DC?,5$H8'436F<5>*=B":@F10;DECHA2DEG495!"-B<3)AF:8AE.,F.#&-H6/;&=6>>3277,>*&F555+6"E12@G%G-8B@91!=8-(1<(<2(>C<?"5!/(,930FE&<-<=0GB'!*<E/A</*)?G%-+3G%,7=
@r2688
GGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATC
+
6C1/%D2DB:C(E"E4@C!&:>,+H<#-C<=,*A&<#C?B<E'*:E3:?G,.?%G?&;;G%24"+0,+E'/6"F*-,4@8/2$!91HA,4G+-!13'6C(&
@r2689
TCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATANCTGGGAACAGAGCGGCAAT
+
D!:-5*7H,>)@3@A.)?!*(,9)/1!#:*6E(BB-%E%!CE+519A95*77EC:,E.4/C/%908./90$5+)/E+%EC8?D*4'0%E)<,
@r2690
AATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCG
+
6AHGE4E&2%D7>"%#@0245@%*+%6.#?>+#*57?0F@=
@r2691
TCNAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTNTATCCCANAACTTCACAACT
+
(*!(*&$$&)+$#$+%)%$!+'$*%*$#)!!%*''!'**(#***+%'&(!!)*"$)!("!')&#
@r2692
ACNCNGACACGTTCAGCCAGCTTCCCAGCCAGNGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGCTGGTGAGCAATGGT
+
))%)&'+)$&%!#)$'&+%#"''$$*)*"("&#+#"#"%!$$($*)%#&!#!)#"+&&*#(&)")#!%)%(#"#$)$!#)*&*&'(#)'+%%%'&('$%&
@r2693
GAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGC
+
.E5:B(@:A$70BE9,$(>(;F%E$C<G774D./"6*+4A@D@74)7*6!F=>?&"'C"D%<,"()4-*"
@r2694
CCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCNACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCC
+
B1:2%2E@(/64%8-!+G.D0"4G$7$59CHF0('B7,(E=GCHH+,!0EFGAG#$)1*>3'/5);1H6)$7-BD6$!%"19E43ED(@(>7??'"?@27=94-3
@r2695
CCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGGANTCCAGATTGTCCTGGGGGCTGCCGCCATTGCC
+
!5*:!:;"E312$/.;.:8<C=!@>GF+>85@)(AEE/C3++8$-2&'C709+B+8H2"%=>?3F:3
@r2696
CTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTNTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTG
+
7'B$4'37(G#8;87<.0&#E!&&#;,0321;5?<<;373/A4),1+"2.+.(@!36"?*+9<#H48E6EA;-:."$EB'D3%B9B$&-<4*04$4$5GE?.#8&A!>:B?9&E/)91>&!GH'50F$829,-!DC*;6E//-3$C-H>7&;C=$F
@r2697
TCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTA
+
/;/&347H="@E5?8%E:%-?2.0.'795+/(2:01392;<9H(6:7DH$'%?)"%HE+8,A'$98%)63)'%;")#/#9GG08>HC-!+(G)1G562C;;-;D,.C8*<?70/G$
@r2698
ACTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAANCTTTGTGTGCCACCCACTACGA
+
#928$93;"8GCE00?<E;EAB/.3;9G5->*5,;?)EB*(@@@>/,!16#C*GFB&GH/E$A"4@?DA
@r2699
NGNNNNNANGANATCGCNGGANCGAGNTNGTTTAGAACGCGAAANNGCGGAAAAAGCAGCAGAGAAGAAACGNCGACGAGAGGAGAAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCNCGCAGTTACTGGATTAAACAAGCCCAACATGNCGTAAACGCCTTCATCAGAGAAAGAGACCGCGA
+
!&!!!$#(")''%#%&&'#%*!*')$*"!$'&%)('%*%'$%&%%+##$&+%+&&"#!+!+&&))&&++*&&(%+$""*%+"%*"$&"$)#')+)#&&&$%*#%')'!+%#"*)'*)((*$!"*&+!!(+(#$+$'&%*"##&)!*(&)$*')$')&)("+"'&)%*!*(""%*(&$!&'%!$$&'%!)*)%%*$+'%
@r2700
GNGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTACTGGAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGNGT
+
%%,##B@*H2.;"&$<$=48/+;G$:C6D2C>?;CD"*H/76F7B/61;'"HB<@68G9D4)<='40;'73C=2*);4@/ABE1A->0;#@C9/B7>G/
@r2701
GGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTN
+
F#6;@,HFH9@!-E(5$(6H10$H"&2A;8=9-?,.&=G3.&./BHH=C.;*!,"$>@!G#+!H.?9<7B07&
@r2702
TTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCG
+
1))3=*5,,+<;2G5+551('FH%<9C</D/0>D-:460!/B4
@r2703
GATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATCTAGTATCGCCGAACGATTAGCTCTTCANGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCAC
+
*+#*''"&'*'*'('#&%*%!%++(%!(*'%&%#(+%$+"%&)*%#**(%!&!*$%(('*%$(+#("*+"*&+*&!$")+"$&&')#*#"%$##$$$!##(&((&"#&('+)"('*)'$()+)*"))$
@r2704
NTTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACA
+
!$+&#'%($"!"$&)%(*+*&&"&$$%%"!'("$"+"&$%+$&%$%$+%(%*+!")+&$"##*!&(!")'&*!#%%)&+#
@r2705
NCNATNAAAANGNTGGCGATCNNTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCC
+
%)!'&%'&*"$)!'%'&(($"#"$+$(%*"!%)#*++")#+!&"('*"#!%$'&!*)&'(&(!+)"&'*+$)")!+'"!++%!+(()%*"#)%)""%#""
@r2706
GAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCA
+
9@),9*49.4*A7-3>0,E!"=G58F#FE8-H!;$05?'(-+;6<
@r2707
GCCGTGCTGCCGGTGTCCGGCACGCTGGTCANCCGGACGCGGGCGCTGCAGCCGTACTC
+
HB3D?2/:>=12*!D;G"H=;0(1C7'@(E>H5+8&*>/)0+A?05%23B79*H36/EB
@r2708
CATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGANGCACTCANCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAA
+
>%>G'.,D)06)#A7@+"-+G("1,D-4<62*B4D=/77(H6E3*(1C'6#495)63(HB804F-'6'0C>G#0;*D5.FF++@;B+DDEAH&@D,-?<""@35A:2)"G7AH-'G%<96+;<*E$'!/@F!A=/'%/BD?F(58&=12)EDF
@r2709
CTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATG
+
(C5G"(/C/(G(,D'-+"-86,F&3*!?D+.H4$B3/G>+:&C493HB0."'##:8,12*57+C);<82GA-$";.*E&,"=2,2?!5#(5/D'0)2?D/';)!
@r2710
AAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACNTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTNTTCCTCC
+
>''7,*'4"B1@$GD.E,*&9H9CG:4')E&*CA!.2*(.$E)"3%#AB&+!!.)6099814(+.@E3*/:=.;>:,$B#1EC8&D;#"C@EF&@,HG(8*'&<*<1#2+')*""A1F<1!7.@:/.G7')DC/:2&56%A:
@r2711
CATCACTTTTCATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGAT
+
,%(>06A34?/9(<D12*=;<F!F?52E=+$8=;4+E)"H'E5H9/%4A876;G42'4?H3$%,FF##6=#16@=29<C>1A"$A4,8F5H*':G!G)77(-.E6*?")%$-+.#-+&B(:@;>;36.!*('BHB$0&1%#0)-B?D,A<5*6<D*0;:A0,;,1BE;D'4(1B<:5?8%GG!&5(*A.)*5C)"&57?.HAC#9E7*5+,0F$(,
@r2712
CCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTC
+
9#%,8?=4C!,;'+-8)1&*BGB=+CA$94F!1$!#9G)B;!,@>89
@r2713
GATGTCGANAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCT
+
4<CA6#/B:G;?>089H45D=#2!>4H"*09/,=:??*),+=H58A0?)3/@
@r2714
TGCATNCCNTTCCGCCATAACTGTAGTGAATGTCTGTTATG
+
&)'((%**%'('#+#")*$)#+#$'%+$+!$%*)#$+!($%
@r2715
GGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCA
+
:4B@)=95=>70F(#)E7<A-C@B52;8/=$?@$D:+6,1H+8/B="-3$)$BG#
@r2716
ACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAG
+
$A/E*C.'*A+8++2(/>5,.)@;")-=%=,+H5*&1(-E:2C>+9.=1D&@>0H.B
@r2717
TACCGGCCGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGC
+
?.+2A#:.;G&BC9%/F&1-+'+B=52=4?&'5')(:A+EBE.H,D=2$4("7/8F%C;@5B
@r2718
GCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAAT
+
-G"5-#0G87DADF'>EG0EG2:A;7D/-,9:A*1%-#)>/8>=-G0G8?(B%E"=G/8?"-0?.4E>35=+#90##H:E;E*;CD)E1D)F8><"$@)8<0..E/-.E7,A,0'H$&?FA-(,3(A$31H3
@r2719
ACGTGAGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTNCTCCCGGATTCAGTGAT
+
A'B=4>5*;-)-/,$!3@;%4B2)42$@4'>&5B%":/F+8A"B)#?FE;FA02G921#0'#>&"G;=5!A=5,F;%'!
@r2720
TCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGATCACCA
+
DH<45$0-5;6&7$&?.4E&BB"A&1@G=3ACF#29C6*B;'
@r2721
ATATTTCCTTATAACTTTTACGAAAGCGTTTCTTTGAGTAATCACTTCACTCAA
+
)+@"B<0:2:D?,!G>+H2.:-7A:)8@;//C-+GA+&CEC-'#18224B7%6B
@r2722
TGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGG
+
9D!9C-AGE6;5",A5<4CHHBE>=?D%%5!C)3/F:*:1FD:!C&.AG=H$DE3G0
@r2723
AGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACA
+
*($+%'%+")"%#))"&%!++!)&(!$'&$*+(%*'*+%%+$
@r2724
CAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGG
+
A5E&=15/A6E<0*!+63-1$/D:4;?80><41,9-D26-/6('!/:3%$.9(E-#)#E+!';E#B2?BH1;;#8
@r2725
NACCTTTACCGCTGATTCGTGGAACAGATACTCTCNTCGATCCTTAACC
+
#D==/@94H>+-907;9H&C!@?4D@-D3B/,6/C(A38;8C&-,B@7?
@r2726
TGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCG
+
1F(G$?(+,0(%D+=DH0;1>C+0C+?1)95+A8:H$'?+>12*7F,DB?#!6)$8:04''C";:;F>+G17@:"F;3*<;E-<-+)(:EH:('"4H9,&>H=6(#@%+/&05<&5
@r2727
GGCGNNAGNGGTTATAGCGGTCCGTCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAA
+
$&%'!$#)#+$)%%)!*$(&"+%()$!$))(&$)++'&!))*&"!*$+&+"*&!!$)$#+!"%*!#&&(!!*%''
@r2728
CACCACGCATTGCTTGTGAATATTGCGTTCATAAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGT
+
4*"8D/EFA0*E1=?,-=*4./>$0:<B.)3023F>#$?=;%,:/BC/67#)"#!.),H)//.29"H;28F=@@4)78>#E7AH!GH!%!6C+94&9F$&::&:B<=0>*=!@8!<2+G4/#H>0:77?=*
@r2729
ATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTCACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAA
+
=;7+6-A:G6-:?/<=2<(%5GG)1G*)C(.CA'@10@.B<14@H%/G$/:!B-F47G14?3A9A!+H;40&(!/,<C74-12=./2C/)C(F:%7H=;()GH+@9#*'<
@r2730
TGAGTTGAAATTTCATATTGTNAATATTTATTAATGTTTGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGATTGTCCGGGAATAATTAAAACGA
+
+<:0"@%(#7,84/H#04C&!?H.)=+2?H&>8GE7#?0?F8!#&3@0./F9BDG=>F8>01A$;;.71$6116B8<"&H-#)3:3>-FH!0"%8!29/%,4;A!?;8@FD41!;;@!)A<"FA!39$$*90:'5@?=
@r2731
ATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGT
+
=!7#+/@&09$@?33#A/!282)BCH2('>@/#H>F6%2*3=7&417)HB;29?!15'EFG"9/+D@C/$=
@r2732
GCNCNNCACGCCNCNGGGGATGAACCATTTGCATACATTCA
+
(("(%'*&(*()$'#&)+($()"&+)%"#%%''(()##+$&
@r2733
GACNGCNATANNNTNGTGTNNANNAGGNCTANTNATNNNCAGCNNACAANANNNGGNGNTNCNNTNNNTNANAA
+
#!$!"$"$##!!"!#!#$$"$"#"$$!##$!!#$#!##"#"!$!"!$#"!"!!"##!"!$$""##"#!$$#!##
@r2734
NCNTNTCCCNCCACCGCGGCCACGAGAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCNGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTC
+
&#$"&#%&'!++)'#""$+)!&%)#!(!*)%)'!'!'#*)*"*$"+(#+"'+&"%&!"#'"!+'(&(+"!(#'*+")'*$"%&*()%+!&%*!))(*#+#+&%(#+))**!*$+$*$("$*$(%"&'()'#*!!$+%%)$)%!(#&!)!$%%&"+#'*"(""%$+%'"*&))#
@r2735
TCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCNGTCAGGAAGAACTGAACAAGGCGCTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGAGAGTCGTCACGAAGACAGTGCTCATGCTGCCCNGCTGAC
+
*0,EA323,-83+#$8324?$4.D@D90'.,7=&>E1#3%DE<!3DEB1C0$2F0.@:B,77<3,>;A!BCB3*/?G&*.G'0-8.2C83@-3E73C@>ED2,4-!2<H"GD:*-0=!@=9FA2=&F8+B)F40>;G8F)G'/G05.!H3#/F%1.1:?!E0D"456/8>@7?@(0688=@)A>H9@"*'18!859.D>2%<-A%://-(("-:@8&?F?-&;C<394$#('5+G:C.0(=8&,G!GC??@6?H=
@r2736
ACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACAGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATAT
+
+!?&='.E-1'@"=36311.';*E:*&$9,3-C16"-+.C,HG#6G2=%2.HFB,:BB'.2'3'$#F9-)+<$1-.91>&0;)*4G,?8G6'-A47E7#ED8:<.>E?*706GH6.G;:F6A/,0;'
@r2737
GGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTA
+
=$C.(+2*3,.3"&26*,5G>=?*/5C.A6B"%!+-8<GB.8?&1C&">(#401@+
@r2738
CGAGNNTTGCCNNGTNTCTCNTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCG
+
()#""!)%"%'"!*%+*%!#(!(!))$'*)'*("*%&*!'!&!"!*""%#'*$%"'(%$$*'#*!!"('%*(!('))*
@r2739
AGGGGGGCATTGTTTGGTAGGTGAGAGATCTGGATTGCTANGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTNATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAAC
+
;,D;.3?)&*.5CA.5+@+E.G(2*#C*$!47%*.;72+8+;898(!<74BD!F9$,@;>&*5'B7.3$%*59+F10%#-<A1#>.+2!-763-.0G@='A&>,-1:1=)$80H?EH<<38G
@r2740
ACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGC
+
;%<&)49!30&+H/E-;C):<;&C7.F/8:;3:DB0=H,D'D*/"&?<'D")(A8%D)*($":;F#!$*FE1B@=;=*B'+:=<8<'H73@818:'7)<7B67G9#-5*B1>%,7C6B30C:H:';9<7?E5*(39C@7,947-'/$'@%++6?<(!10-6,#(7*G<GB:':3"4?;-&9(H&H<#07F<35!8A<C7A1/8FD%7,+?CC5<+/5.H6>58H-=E-&&1C!6H9)B77$+&3'82,-3("4AA-4F=<=*;1*D9.(H(+4.2CEH*4:,;DE%1@G:,10>8C
@r2741
NNCGACTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAAC
+
!!$&+&#(*((%$)*(!('!#+#(#((*#'%"%*#&+"*%'!'$"))*'!!
@r2742
CAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAANTT
+
-)@&!(D3);!/'7B$-@&3555=9C.4968?(!:2>%.C4%@?ED!>B6F6A8
@r2743
AATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGGANCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGC
+
GH-?@3"04=-'D)<A=?@!#83@+4/*:)8>@!)2<G;>,3;A@=HF&&8+,/$C7*72BDD,>>C0>537!$@H-F8:76?C48953BG1F.,=<C=@;6-DF9?4?H!#+6/8EA/8H@G>4!
@r2744
GCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTATCCACCGCGA
+
%G*);@$7E;$89;@5B=/6E?*<0577.'/)?*?!!2H&,D>74703HC6;G?/A9;=C77CG2<97DC(94E,''
@r2745
TNCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGNCAATTTTCGCCTNCCACGTCTCACCGAGCG
+
"*5-6"1GG(H,,!%A0B"<F872H!76!0:CD*+3B%G:C;!*'@FA,;7;#:99&-),10&/+B%??:9'6
@r2746
NACGAAAGCGTCCGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAATGCCGGTCGTGCAGCT
+
#$(+%!&%''"$*)%+$)%&)()&"#$#!%+$*(*&)"(')*!!!!&#+'''#!*)%#)$!&#"))!!%")))''!$#&(+%!"%!$(')%&'(+*%$)!%)+!'!
@r2747
GCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGAC
+
==0,@D<=:G7:9BD:5%25+F$<$!!=/?$*-&6*DE@?@9,;$'D1>((0>*F45')8",4(B
@r2748
TGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAG
+
-0../BH*E6C7:57-HEB06C-?A$.>>E3=E'+>21"(?12/3F=;H9C9"",C5;@1:HE42%"!7+H<0(=8F'!C/EG"(8')''?#
@r2749
GCACGCAATGGTGTAGCAATAATTGCAACTCTTTCCCCAGTAGTACTGCAAGAGGT
+
BD3/+?"!6?(./$CE.G,'=&@(</28%,22))/,$:<$8E7,>=5(+4,<3+B$
@r2750
GAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGNACANTACCAGGACTATCCGTATGACTACG
+
:HA!">H.(:(23>C5'=<=@6,>*3A":6ACA3=B(/$,67>;5"5'0/(9&C)H:>%<$E4#5D11D;(G
@r2751
GNTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGNTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTCTGTCCGTGGAATGAACAATGGAAGTCAACAANAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGG
+
D2A1-3B*,B@A);)>C/;E'@'C4/>,(!#>+2@&1?7?32.C#E=':$50HD:7A%,15?<+0B';G4*<'9HA>>.#>5GF89.6A8<7,B-9*.6A%@4/8@4<1&0-61E;;=,3*5'#E;D@#-$,&";C&A*-0B#4@+7%.C#@!--:'7'B57H>(-17EC<'%/=.),360.7B!<$#0A$:'G9(9HB&7;3GA5,!))<?<48!">:C*,144/-6#<D>>A-0()>0>,:5&**F#3)'CAF.B8F:)$+;$5A2=24#,3G'&3BA
@r2752
GGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGNTGACCANCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAAGTCACGCCCTTCACCACCTTCGGT
+
>>:-7H;9.?D.EH$0H$(7',9?:?<2#13:0E",:CG-<%:7=:0">3G4"@29*E."770/?9:,7'.>!CA0&A83<#<H$/!E?750#8'6;392*042,-B57<$24.BA<;9,,4F="G6.A)%929"8),3#@$.659=26*9FA:7(4/(?*1.#56H#B32<,0@+CH<:$)943$1)*$=EA"DG;44E59!9.$'D3%;2D,$@"72+!'060$8H:B7#*FCC/)A3*+?%2$$"BE'B&H%5BA!;>/E,=1G7)820840.B,70
@r2753
GGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCAATACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGG
+
)F.%(+GAD=5)1@@%:&?$!,+3A&1-C+4.C/;B=9D+3%(4?8$E8.%@=.9D>-#A4*B6,%1#40$'=E'#BEH896)-E1)A&7';&16/H&(D596:.42(&E;>?2F+:=@-,,5/+D45F9+D
@r2754
CATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGNAAATGA
+
E/?;<D7>*-(2=G;)D*&8D,0#H$:G44&+/%F4BDF,!2"<0=)!<(F/'?9G(AE,5/>)@0H06G*!"@"@B1;-3(,
@r2755
ATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGANNGAAAATCCCCTAAAACGAGGGA
+
;D?)&?;#616!5<&+6(+FA!./0#)?#EC(?8:.;D%4A?*,<(=%)@H/FG855@A/,+9?"4-%""+#:',B-'259&E98>'22?<F(B$
@r2756
ACGCTCCAGAATGCCAGCAGGACCGCACTTTGNTACGCAACCAATACTA
+
$*19H*$!9C0*930)*#%82&$!F#6.'#C20H0:!::1:2(%@F1&.
@r2757
TAACTTGGCTGAAGCCNCCTTGCACTCGTCTATGTATCCATTGAGC
+
AE8@D:@#=.#?+E%.$$!@1G9;)!5'%G7#+H357-540C@BG(
@r2758
ATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGG
+
*#%8'AC#*79$+07/!<36%7+F$8(062'@3>-=F<(-:F21*9D&C@(4.
@r2759
TATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCGGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGC
+
A"+/:ADE<&1B!,'H>=4D@D1<C6<>=,!G08A%&A'&9$(H2#2"@3$:*9B'??14D6<C0ED.6)C/+7F62+E+$??)A4$!>4/:@H,7'3H(='*&*0+H?A=%947)@">*173D")F?;;-:E'
@r2760
NTTTTGACGCCGTTTTCCACGTACTGTCCGGAATGCACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGC
+
!'(&#+!!#'*!(!*''(&&%&#+%+&'&!')$$(''#%#!&+*%$)+#$*)*#%#*%""+!*"'$#$''+"'")")+$)
@r2761
CNCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACTGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCNTCAACGCTAACTTTGANAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGAATTGATGCCATTAAATAAAGCACCAACGCCTGACT
+
&!)+)!*&!+(+#'!&()("&#!!"!!##)&)(!'*!%$!%)%)!'%!#(*%(#(+*'$%+$%$$#%$)%*"&)&'!!!(''*&'#%)!#"*)$")%)(!(!*)'""'+&$((&*&#&+)")+)()"+(%*"*(!((+*!"*"&"("&$%'+$#'&+#)%&'"#!(&*')'!)$&#&$$(##&$$$()*"!%(((#"$")&(%&$$
@r2762
TAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGNAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATTATGGTTATGACGTCATTNTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAAT
+
-A@#0">39E%H2443!0F,@67>0,D:'C+%52))G<$<><$22412A+@9)$C!4;(@B9.'-B=55?*7@;%.:*@8G7%+&&5:C;7953*-!BD0D72*'=0'&&<$BH9?/-7%<38(03%6"3,?%H.+=98DAG.'?@FA4(4/.+,GD?!GD#D><:#?;.2@>'.>0-!'(:B";%EAD&&92"978A0C1
@r2763
CCCCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGNCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTNACCCCACAAAAAAGCCCACCGGTTNCG
+
'"&$'(+#+(+)%'+!!)""##+"$)+)($%)(#)"*"+#**%%(#&$#('+$$!)")$+'(%!"%!)!($(%"$!)$+!+"$%#'#*#%**'%&*+&!+%(#+&%!+$!(&'$!%$%#%!)&(&#)"&$"'"'!'#&(*"##''
@r2764
AAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCANCTGGCGCTGGGGAACTACAGGCTGACAGTCCG
+
;A?@-BH@(!%;77%84;90D'9*"!1(*G<<6.FG<5$?D>$B<0C,90A@H@=."48A:6,A5#-2?./;H)%<$:-7=%/()984<=";A;9?-7#+#=3*C,2$DHBFFG/<97.157%E4)'+/B#G)0;"3G9>&"=5?#
@r2765
GTCGTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCT
+
(*)+!%+*"%&*(&(&#'"(!+"%)'('!&'&"(+&"'!+%
@r2766
TCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTAT
+
18#;7%?"%8-6;6-239=+"?5:#3"D?'%*=/<)%'#85)'6H':?1("9<B'?!73EF-0:6,(0H
@r2767
CTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAG
+
2A:3E*$'!9=#=68#,F:57)?/)3E*G8.@)&E#$1'(.1<2+$-4B
@r2768
AACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCT
+
.'&<;H.8-;7C'$#4:544/!'%/@43:"+12:AFE)<2)9(%)F'@$$H./6:C9#?8@1G
@r2769
CCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACNTGACCTTCGTGAAAGCGNGTGGCAGGAGGTCGCGCTAAC
+
4,%;H<#>//"1D615*6;*064?E4@$8E6H;*4(B66G=6>'>&E;=C#&,E+%-(<=233;6E+>'@B%..E9+82@93(1GA=E4?:$=AH+(<
@r2770
AGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGCAGACAAACTCACC
+
8?3?GFD@1D8"?EE4;+DF$=3&32:0>@7$EGA"5&G/6GB<55,'(77'D)1D!@
@r2771
CGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCNTTCC
+
&,?$3<<E#0A<C:/FBB>;E2.*&%,&A:$7*0(5H8.A:B+*/4G;,8)?
@r2772
CACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTNCAGTTCT
+
+"))))%')"#$')+#+!#&#%$"!(!+%%'"##%*$&&*'*!&""#$
@r2773
ACACTCTGGATAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGC
+
HD.>CA@,"$?>9"++:.=)5($,941;H=@<2F)@3%,?DDC*F#DB60-!.8FE
@r2774
CGTTACGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACG
+
8$.A6=BG6/CE"#0E;4+2:FD>2ACC4&,A$F5<E/1B4H7!$!6H#',6H.7#515C!18*/2GH45G7/*H5'"G=5-?#+.)?#+99C.=<6+(;
@r2775
TGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGTTTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCG
+
<(1:?-+.,%#6(&C&+79<*B8+'7!9,'A*5BE-<=?H?7GH>H/>H@"/8"/3,;#F.@A28:0C12-+4AC$B$,'5?>D,?6-&C6+F)%8BF?51*";<6*
@r2776
GATATGACTATCAAGGCCGCCTGAGTGNGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTG
+
/"1/9*+H6#"GH@;H!FF5+EE<?C,F#@'B*(:D$,-5)'!:D<AG8)+C.*A5F!8-&$3F,7B<5C5=1C!DC+*"A9"H"D7,8?849+-DG.3('!A=:.8&=0@>D6=F-2"H!G:B..B@6321,H7$'$#DH#EE-:,D<<9,HB,,
@r2777
TAAAGGAAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGG
+
F4BHFGB>GC1A+E9#1AAC,F*=5)>E17A0160314+84;;<?;++@.5@-61;
@r2778
NCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTG
+
"G?$,5"A+A36D9$0B<%).D/,%<>2F;4CD0-4!+0&11
@r2779
GCATACAAATAAACAATCCAATGGGTGACGATGNGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACATATTTAAC
+
D/*1A=#E@9=6/@#.;@;!6>C=1FF9;3C#>E9;-"-89&-F+D@2CA)<@$<:2$B4F2*&!%!C(.)#D3D',A$*G:,+:6@F4;?:>>
@r2780
GATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGC
+
+""$*'#++')!'+%%(!")'!()&""&+'"%&!*%!""**+$$'$()#!'**!
@r2781
GCCGTTTCNTCAGGGCGAGNTGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTTTGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGN
+
?)"#BE:,!;0;<BD521),8/,2<H;!<D*<5!4>@#95G6.'(D29B=B:3"D%7:=!=F?FH%&.G073$1?8)2.H><7?=*##F)E18,<9F?..3?#08"@DF0%&03B(.%.1*5+C$EE
@r2782
GNTAGCAAAAATTCTCANAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAG
+
&*%#$'+'++***'$#&($!))#+''*#)%#)%%&)&**+%')#$)++#++*'&*$#++*&)$)"#*())'*)(%((*"#!%&#%")&&'#%)('+&*+#%(*#"($$(*'%)#+
@r2783
GTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTANCGATTTCGGTAAGGTAAACC
+
H94::)-4&-<!)6<%C;;>B'?2(0;$$=5A!>A2>D9B+81&((8H9E"2$@$';GC<+C07924FBC*.849+<E%!H=512>=C/(?G"&7%3D:E:>?
@r2784
ATTATTTTTAACCCGTCACCTCAATTNTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTT
+
@"H!H<1'1&130$EC7G(&04-3/<H#)./,H:.#&2&D@E4#%H&F!-E=?*4F&4"!)#A'4*A?+6
@r2785
GAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATANAAAAACAAGNCGATTTAGAAATGTATAGCGAGGCAACGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAA
+
5@=&G,F3D4?291-6F9.:+3-6C&7&#"'!*7H@2,>*<*07B<E!*2?E?204+>F@BD!,F880!05+'>;2'GE?84;D2/:157*%.F;.7HAB)GF!C1."7:B85A.@&B)A8?-F(4$,"-C8%+((<F@!21%-?)))A4+?>DE-!2<!$G:!4B=:!3!!'=570)6<,*,$:);(-?@->(8
@r2786
TTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACNGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCT
+
)C8G6,"$B/30H:C</8*+)E,/$;:6B*G#3,?EF)>0$/9?C%&$@,'07;%D8);BF7D9HF%'D!FE/2&>A#@2(8:+9>##?D"H)9>@+698F(&2+,!<0D1-G&/14?()F/7-F48*$!.,2-&,/7H=9A025-E=:(,'39)G4?B1)5#60<.2F-G'?3**CBA+C"B-G(H%@(*5F8'&:"3<@C956=:#9C!$><!9*0.$,+'898BGA&?/$A?"(,H1?3/)%)C0G:9+-509(C:/5(8B5,E>G?1?,*&>)3:/+0?9>?>:3770&1+9#27".(29+9?&3:-.&71##!4&8!$F**<-,(;:B
@r2787
TNTGCANTTCNCACGTTTACNNNNCANAANCAANCGGCAGCAGTAG
+
*)")(%##%#"!)('('%')$#%!%)#*'(+'#*)'+''''($#)*
@r2788
CAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATNAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTGGACGCCGGCAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCNTGGCTTTATCTCAATATTATATGGATCATAG
+
"50DB?C/-0/4E-55+&0@@8B4!+":@'67<;FGC*E3'%"722$+673F@>9="-6)BFF45$>D=/B)+E1!F/8.B3E:A(!>",#&H(D%%=9**+@9@CG#/''6*6EFH"4E5+,1&@A?=F+9?<6F4$>51?*1(B/#>@3%@+A08E#A?#3<HH36G62#)56C6CH."86,?=8E.>:1
@r2789
TNCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCT
+
($'+)&"($%&$)&)!&*#&+*(*%%$&)&&!&%(!'((%"+**("%%%*+'$'&!$('!%%)##!#%#"%!
@r2790
CCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTT
+
90D9+CD5+!@,%@%9A3FC&6-*;:!2A44,+@>3G."1;F9,#67B?F1,>0B$&2,$+H<GGH4HBC"&H-<.DE6:
@r2791
TTGCANCNTNATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAAGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGAT
+
!*$!'!!"*+&'!)(+&%#)(*##'&'""&'"%&'*$$''&#"$')%(%'%!*(&**'$''!&%!'(#"*+'%*)&+"+(%!!'&)('%!)++*%#&)*('*%#($)+'!#"&+#*%"+!('$"&%!"&
@r2792
TCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGNAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCC
+
,>>C0&FE!'8AB<C%"<%*.7G4%++!4'(7$35:#;E1*)7(CH.&53&8+-@8(CD/;.F:"$=.;#*6(=?(2B27<FA6!6C/#F$CG#7':B:1:34EB5=)))3F%0@:1:BA6/'.&3E2:;/-<%1+GHD=*H@;.)0AE#$B3#1D?H
@r2793
GNAANNNTNGAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTA
+
*!$&!!!%$%+)$*#%$&%'"*(('!%+*%%+(!'"&""$+$$+)+')$*""'"*())')&($)&%""%')'"$'$%*#(+*"%&#!&'!#!+*('+%#*!)**$%()(!#"#!'*'+#(*$)'$"'"+'"("!%$'+&'&%#$+)""*
@r2794
CCTAATTAAATAGAGCAAATCCCCTTATTNGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCAT
+
,;<E93H>3+7@G)7:4>C!;/(6?3-.0A4D/6'!EGB*E/@H-H##-2;@2#)@+$3!D0(++11'=DCC?3'F!%
@r2795
TATTGATTAANTCAATTGGATGGAATTGTTTATCATAAAAAATTAATG
+
=HG&9:;32%H%6'3=F#=D0><.189>E!)'(<7865%A;D4#(CE0
@r2796
CCCGCGAGGTCGCCGCCCGTCACTGCAGANAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTNAAGGG
+
+(!+C0$78A(*>F0:DD';45+:@&*$FG7-=-?,,G<!5?CE..='4F9;""4@#.-+C$*9-@46;:9,8'-.9,,(-48
@r2797
NGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGG
+
"A%(E8B"/H@5H'0;)495:,*D#874(4='/+$9:=(@&7#&(+
@r2798
CTGNTGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCNGATTATCCAGATAGAGA
+
#5@>)&&+7<'%.<4'HG-B5+%!#=/!AE-CA<)?B!$<4!7HAE)F%'8;?7:?C*"--!3.3;18:7:DD41!>=,&61C6"<#A,C8#(.?=<2
@r2799
ACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTANGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTNTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTA
+
@>560BA<8<(&9G0+#1.GC*(.4>5;>&>5@@0=-*-#1((@A@7+#;$%0/$)3:A-@G$;(4,<?&(3.=H3)?*;85*D3E43<)-:+)8B=E@%$/6!5!#B>$H7&62@7?.6'</$91-E8=+CH<5H6CA@G;GA/(%%==F+--4#!)D.#'!?0"@<E#@.%-+.@FB:A.#0$BD;@6->=FG>",#,'F2@;#<F831G90#.!/??2
@r2800
GAATGCCAGAGACTCCGCTGAAGTGGTGGACACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATG
+
?</-,2G>B#'D0:)*=>)2&(+G<-;*;("!-.=0:(8C3.'2E$<0@GD5C!7ED)'!3;*$+.%"B03$)7;.>8(B@$8"2;&G?##1%&$040%BG869'H4F+A9-'-&;H--A$>3H7E=#>H=G3&*/:4FB!<7
@r2801
NGTCATNGGCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATG
+
%)!%)""'$+)#&!&&)%++&#'+(%'*"*%%)((##+)!('&'*!!#$+('#)*('#*(+'&#)())"*+$'%'&&)!(
@r2802
CGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTC
+
1F;AB5;D<,E%E7B7%B-&;A&"@5$@73&#@!:2#(=<)GG,5!3(/)B%2)2
@r2803
GGTGTTGNCATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCGAAG
+
GF+/9>2BFF.3::.@3<;?+$>H,F*:E1;"%$D76<@H'+<F0'B/'D,H?'9?5HH@D3)&%@/*/233C.>'A@7G)63&"/+=2-"*/4+H0".5?+/$+*#0H?6#+%
@r2804
TTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCANGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGNAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCANTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGTCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATGAGATATCTTGCTGAACTGTCAGACTTTGAGAA
+
.C$2,H5&23<+#?+E,$?4B;##E+7#D#3(75?.D1+970:19/%!H0F.G.62!*A*"D;;H6539;F7770C>9F%9!)$&F#$>0&6)))B>%D3(G5=E852@2$0?6)8-<2&C2C4'>G9=&%)-(E;=1<"#78&5#%=H#A9,1D3&G%A,HDF9+00HA93HD)#.1.,%;@)).-G+)9,3#1+";2*"4B1!'A(EG0'24?F*!H"?$G">,H/;4:7*8;9E-'7DGE=5H@92%94>D<*6-=CEDDGE='C?&B80<>/9BG$85E"(9---;D&,H;F4+H;-?<G8F)8"+&.(>(&+'!>&;:*+H@+H:21&476@,9H
@r2805
ACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGT
+
H:D@B-.@75B*G$5#&66#%;0CC5.<(20G:8.E8,D4,F.':,+?(@><H2F1D"*('CG2--$,=0>6?8>:?>;;5/1.'%2
@r2806
NNNATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGC
+
$$(&+$"'!+%$&&!((&($"$'$&$*#"$)"$#+()#'&++*#"#&!$"*&!$&')
@r2807
CGTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTNTTACGCCTGTTTTGCTTTGCTCGACATAAAGANATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGC
+
""H88$G68>"5F!#F"91H:7BEC;0#4@6DC&;$3?&72HFC0,?+G2@4*4"B"0F'!?18'08?(4$;*:+1$$(-7/9*>(?+$E$/6>!78<-G>7/@AH*FDE2:8,)8#F,>/&2<(1#804&0CD>+"/.136.B+=?%2',9%
@r2808
ACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAA
+
<'8<'0!")55+H7>&''A@(4A3:'4A&*,'GE&#B(69.4D3B(F:E5!!3$9@5,F6@<,H";4)@8+*1/4;5><>;'9+%'-.78(6G>AHG31.
@r2809
TCACTCNAGGCGTTTTTCCTTATGTATAAATAAGGAGCACA
+
F$AD(-,!G%B7A5'C,A/?1$<11&-%2!3=)@3(F7>3,
@r2810
CTTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTNATTCATGAACGNCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCA
+
(:70=130=,1+8(/4D=G9(0-HGG#/?>-CCHA5FC(<H5039EC0%C'*B.E/(F,@?E!+0';D?@D'6/)::?4%"?56<@-.+9,*><60/5-F1,<;.(2H;67-ACG-=83(3A'*$!67&F/H*6!:1G3)#&F<H#>@6?,*FF*EEHD@*16<2;3E=?<&128>)61&(,71@1!@:%"-%3=>&3,(C30
@r2811
CGTTGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTNGTGATCAGTTCCTGTG
+
DH=G3?DD$3";B!#2AC=+3?@68"EG/,GG"7;"E:C+-H6.&4/37DF6;E1GD.>%+E5D#B"'#
@r2812
TCAAAAGGATGNTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCNAGTCCACACTGCTTGCACTCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACANTTTTCAGCTATCGTCACATTACTGAGCGTCCCGG
+
7:G8'7:F9C36G/@9#6H&3&()*2GEA;DB?F(),(A&*1,9;'-'D1D(57@B"8#;24.!5+1-:#@+00,H@%'D<+,/4A/@D#+=#%*A/#/A-8E>$"8:&;'5/C5H*7,HDF;:&->B5A=?>"E-A)3=*>E?6G3)DF@$67!D40,*!C3/14A89862'F?B%%=+>%3"
@r2813
ANATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGNACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGNAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTNATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTNACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGG
+
53$F(#*(*H'G&2B+HC!#C7D4770!A:?A<4G;F"!"795*"34="@#0>"14B+5D));,D*1<ACA,:=H9-5E<-<<#G'D*BA+)2,=%&&!.-G>*16()@>206-%9-#&>/2FBF)=)'C'9179%;<B!B<.9DB2+(:,#'46:>CC:CA!8:185>41,-7(-FF&=(%'G#7-#6)!%$4;'AF7DG8.&H:$?9G(AD3&?G1>.?*)):G/*>/-'41-A,1@8.873BE93-:(1)A.HA++!;3</6"+DE@F+H,+'7:B-7(+*8H"!HC$3?2#3!!'15$@:+5@#<*3<G%:%9):DBE,32'+!=-C".(0@C=#8,76'-81-%"1*1@(93;8,C19<F*&!@GB0/0#'-.,9;8>#$,3G$H%%(428<>
@r2814
GCCGCATCGACCTTCGTGTGAAANCGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCTGCGTTTCGTNAGAAACTG
+
:C#2'%2<B$8A,<.329%48#*:==@&"'-27,9:C$'7=8F2?8%"E<3#HH-2.&=;D1(<>"%*F7?':(7,$24G?#2
@r2815
CATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAG
+
!(B4B@+=6F%D&'=?B&H#0:&86(G;<2%&5B*C66E)?=3)B2D$>!9E7(3(.'>:@E='$*="&<
@r2816
GTTTTCGTCNTCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACNTAAAACCTTCGTAAACACCTC
+
&"+()'"+$"$()+("&'('#')*!!'(&%'!(')&&%&*!('!$&$%*)*+)('#"#*)+"+*%)("&&$()'''&+!$$#'('$"(&%##'*"$&'*!&##'#*%!+")#*$&&&"'"!)*+#+#&$!'++(("&))%'%'%+%*+!$'"!%%'
@r2817
GGTCGTAGTTGGCAAAGTACCAGGNATTTTTTCGCGTCACCCACATGCTGTAC
+
1D=+6.H'=,4)F;(H4:H376+G@+"AB52,+=C#8/3=,@/%=%<EG()0,
@r2818
GNTAANTTATCTTGCTNCTCNTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTA
+
%!$*("!%%#!)#(&*!'+)(#+))%$$'&!!!$!#(!!$&*%"$(&&&')*#!%!$$%*$$&#))**
@r2819
GANANCCCAGTAACGCGCCCGCGCTTCATCGNTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAG
+
!(&(+&(+'!*%#+")**'!)#**$"'+(()&*#"!(+#$$"$%+&$!(%!)*$%%'))%"()$"'#*"#!+*%)(**#"&%+$'"$'&+&&&$%&+*''*&&"+
@r2820
TGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGATATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGT
+
?#)'8/>A93GB$6(=#%+AH)1@6,<21DC=)=&@E0=%:;36>?6E164+?D!,')<F(D&A7%$332EE:C'>08B+!%"#*7.4*>&(D&6/%
@r2821
GGGGGGATTGGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTT
+
B"$!$>A.(-#.<!;?,G),+(?G81F71,=4&%(><;E4./=.FD!4
@r2822
AACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTTGCACTCCAGA
+
9!@A?9A6(0H+>B7E-&C7-!2?F"?08(#G.B5GDDG,!4F>!5=8E8*&#11;/)A+-F?01=:H009DG99!0'7;>)+#D/@GC(H;BF";$5G;/8
@r2823
NTNGGNTNNNCNCNANNTNCNATNANACGTNGCGTNGANCN
+
"$##"!#!""$"""#$!!!"!$##!"!#$"##"##!"$$!"
@r2824
TNATTTACANCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGNCCGGGAGACACTGCA
+
"!+#$"+++%"'$+&+"'#+'$+#&!((*)*+"$%&+))%$"'*+!'()+*(!"++(#%##'#$%$("*&''&*#&
@r2825
TACNACTGNCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGNGTNC
+
&%'!*)%%)+!)$")$(('"&%&+++(!**#!*#!(!%"+#%&*(('%###&%$)'
@r2826
TGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCA
+
8#(11%A8F9#CF#/8#-#5$2+-G"58D/4@(->C"2@2.*%*3(=98#)&?,2@&*,=G!
@r2827
GCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTNGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATTAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGG
+
/BG-.%="-0!!88>(=-(,"H/37+$<9C"8..8:<(1:5&#G'+="C6$%H4E<48?!D91,*,$%#(/*-+:;42"1%/(+A1*!="/872-9H5AEF!")G.6)B3@/'DG*7'EE607-G#8&=)>>%D>%(7ED(3:D;*%"-4308&"#:-.:):471(8-&/4A92!1=DC<,=2%96;>0=3@7"-;D=:D268>5:0(6!>
@r2828
CGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCNTACGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCG
+
F/7C/2$E@E%?(7D<097?A$+403E*2,2>*A0,0E;E8-389#B5?6+5G83/B.,4(,/E*8F<5&B;$58G-E0A.>H$;-C&0,'5-6&B9F%B9!(!C8."G92;=9<8@:%8EG+7A**E:H
@r2829
GTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACG
+
4G.;3;)!)."02:;61A<:";!3#GB%6>'-566:803>906BD!-3G>1?);0A-A/2
@r2830
GCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATG
+
2/F$3%=)7>*C*8)-,$.%!+G&?*B5AA29";49CA!6
@r2831
CTGCCAGGTATCGCTGTCCNGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCC
+
?G0EF4D6&0(3!8<#394-@G0)"7=(H<(EH'+"F$$*!C6>CBG">@&C-,8!4*2&7:818#B,:A9B9F/;
@r2832
CGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCT
+
4)+/,3B$'+-<&#2=-?>*/&0!1:+EE>20*B<=!#$!4E"47
@r2833
GCGTNGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCG
+
>(<-(3&#(D)3.G,6**&+%8#HEH7>="92',47D-*@8,%@++E5;0!/"HGA;:
@r2834
ACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCNATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGCTCCGGCNCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGNCCCAGGTGCAGTACAGCATGTG
+
'G!2#3=7,:@/715(./"D&F7+-%?,D39-8:'HHG=@?17%"$(E9C8#*6E-5(-#1?9%A.?,>;+,5393966.$=9((6"@2=9>2B:89'7+!2#,H+8!0:F3')>E2&'15)/?7>E95&1A;,DG,D?4GE.<,C($<G4$8"64%,#)D+7$"0?75+'&"A:0F&.<1=73$=%A"#/F;G'14!@D$?##0<
@r2835
GATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACC
+
H$&,488@(6$).C77?0D+H<-H!-0H;H"@G,;?0>:4$8%"+!/C?57%;8"?@.3*(>4F@*;C&!<9%,964)4$;90&):EG28A*39$D"5GDB2$22'=-7
@r2836
NACCNGCAGCNAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCNGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCC
+
%''$"+&'$**'#'!)&!!*$(+!&)&($'"##'"&#+'%&#*'*&**$!(%(%""'$#&(!+#!'''%!)$%&%##"))+$#+()$+"&!"#*$"'$++#*&&*$(!*(%$$')""##&!"#%#*'!"%(('!+)#+(%##&)%%&#(')$"+%+*")&&)$&!&#%'+!$")$%#**$("!"%&#("*)'"!'")*##+'!
@r2837
GGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATNCGCTGGCGGCGCT
+
(7+;8&14)/D@;5$2>7:;5.7'F(77$6D"3!G@/?54,':!?F'%/'C&-'A#:03!8>2C3-)6B+.ED=E(?$;D
@r2838
CAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACANACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGNTGCGGTAAGTCGCATA
+
*H/12'-%'.$700>?*GG4$$(ACD,22HA1H=@5!&-;:$.C)!8%.-+G&?0:,'(74**30$;*%/H,E3+E%8)6D%E3:=597+#4.$D3
@r2839
GTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATNGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTNTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTNATCTTTTAATTTAGG
+
2:=*"+7D(+0C@;5=@6@G9;D7=3+!76"0@>)=#5!H&,A1H+5B<64HEC@5*'0>9:?&8&$F.'!9;?49>5,+%D>0A*-7AH"@-:6B&C?"F5)26CDB9>&BE:DD,).*:,3&"9%94D34((?GC1$59?73,)EB&3#8C&F92(=>.-!7F467B#D/F9B'41.@?12%66($<0,"
@r2840
GACGGTGCTGGGTACGGTAGTGAAATATGACNCGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAA
+
7'?=C74"#>)'AC01B@G$77@18-9+5?/D<C0//$B-60#@/G'E@.G%+8+"&4825;9<56E9)-.2;)*",CFH?"B4B88>=8B="'*!FE(HD"65?G3$C?+6
@r2841
TTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTT
+
H8.0',"2'27%022>0%2G?(:EG??0,A>:>=)3$C8-2+#07;3"E9;2>E.DG'10>1:)%>H!E5'1(*09*06HB($5/202)?/E5HC$G&%C!*3;5&2-<(D10>C0!)/3?<&;H.7'13-,5E"7,@
@r2842
ATAAATNTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCA
+
0#7"B,*2EGE@%&51=5=B&E&*)>""-=9A@&1F(AC11F:%*<"B$<=E$=13%B7-*=&!C#:C)7H82G#?"5/D5$-,4
@r2843
CGAAGCCCGGCCCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAAC
+
G><@6%1>)5&%>D')#=&;7G&&AE&%-;'4F;*9GH)H&@%F<53971!!1A@@;4&BB<<<;D'
@r2844
TTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACNGTACTCGTGATAATAATTTTGNACGGTATCAGTCATTTCTCGCACATTGCAGAA
+
>/&&FHG/A(=*6=6&H5+9*30#!5.6*@F!;#@;-@(,*@3E)26$"B."-7(>E)+#E<!$9?+ACC'/0,/<C<(D170477@E&$-C!A@GC*:%@:#3?2G*"G/,33*'H17)(
@r2845
TACAAACGCCAGCTGGCTGCACTTGGCNACAAGGTTACGNATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGNGCAAAACGGGCCGCCATTGATGCGANAAGC
+
)''D$&<3*3*()(7D616#*;#@&<304E<D;F4H83"4:7.."3(,*@@(<8<E6314F">3""B./->=(%.274D7"A$8:;D?5CH@';!,HDH#<4<;%<"#!AH#'@2>"7@*D6";>;C&-
@r2846
TTGCATGTATAGAACATAANGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGANAGTGGTACAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTNATTGATGTATA
+
5)0(7*35)%,')E/4!"%8'%A3G%0/!"8D#/G8"?C,5/0H5F=6?;.-7**<&3)D<<@?7!949/<45'!H*!0@D8G13*"0;DB-9ED3!>0?<D,><,&'EB2-1=E#3(8D)@9.E=(0FG8+E2-/20C!<039:;*2E;BH%2+FB=#8C+G+65H;$H806F@@F>:H(?C1F%62*+6G%!"3'59$(,(A-A/%A@/='-<3B/G8F03#>@/)87*F%28,716C4E*D,)5$*C.>.1G-5$B!B8/:C>+6!A+4>?&-'B-1&5/8!58D!F"26$;@#,"9)
@r2847
AGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTA
+
91%A64:0G@-10+G-,4+HE5!.&"AH/38:=FH,'%C/*,::-G,"
@r2848
AATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATT
+
=A;&:>)#&:-23F,@@:2)G**C@:F@,+A</1A'D<@79*3&=##)$?)A)
@r2849
CGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATAT
+
6!2>E5.7A'4?4*?:B>').=#+&6-:?<=A4D./6:H4>?65/G'&G&2@
@r2850
AAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCNACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACNGGGCAATGGAATGGAGAGCCAATCAACAGAGTTNTCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAANA
+
3;.4$47@;55?!13G*39FH%4A:"7%(1%@A8B1H>"B,'":7EG$,0EH;H6">5D-+>DD1"01(!:GG))G!D>E8*#)H%AH/42#=19+=,+@9'<-C)CE%==A0!?B)8B5CB)=#$D(G,$?B-/",9-4%18&;G-83A?2D@*1DG0?70,+A0!E2=;+D6,H1C.$F0>7A6>73"H!$F"%.A=8*)/6.9'@BH:4++,)7E4:=(FB&D,*FC:G?#.FB%BA?4#B6$56091C<HD8C%-27
@r2851
NCACCAAANACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCNTGCTGCACTGTCAGA
+
!+'%+)$"(%))%!%)&'''(+$'&+#(#*'!*'))!+!)'++*#'!%*"%#&!(!#%''##!&''+!#('+("'")%+*"')"(($+))*$(&)'#%"+%&&$%*!(+'"!%)$#&%''"&$)
@r2852
CATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGGAAGGCGTAAATTTCTTTCGTCNANGGATTAAGGCCGTACTGGTTGGCAA
+
&#+&#+"$"$)!$')&&%+&"'*#()'&!*#")$)(*&"(#(!"'($+)'(#"!!"""%#)"!$$*("#*!$'()$(*+')$$%%*')&(*!#
@r2853
GTCNTAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGNTTCGCNTAAGGGTCACCGCTCNCCTTATAAANCCACAGGGTGGTCCCGGCACTTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATGTCTTAGGTAATGACATAAGTCAGATNGGCTGAACTCCNCAAGCCCGCATCATCGTCGCGCCGGTA
+
5&EEH3)D/45=972F&:(1C51'>57.$;;>%@309)$!H?$C'2,*$-%2)2H#/.?-2)A?<,4.<((A=H::3,G));F!D;E'*9?=?,D%).-#&1(!*B2HE3!B4'=%7=*.F%(31A2=<;#=)6.D73@7!%A1#'42*EE?*-#-<C9-<9GD1;<1),)=(/:8!040F3"4?&!+,%(4)B:>9'9H:7C$@"!-'38-&9#94&C!%6B(H;>":'3B54,4G49.GB3;GHF
@r2854
GGATCTGNACCCGTAATGGCNTTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGAT
+
6C0B)H+<:)336@3?;,0.C9-(&1$<8@!1%,$=%CGB06AD$GA90&&*+(6.;5A6-@3!:A907B)2-0@7+A/5%@;6'1#D9H@HB/2BC35'9%2>6(6<E>-?A1<9D/.379<(:0).E/,/".)86'53+11#,:)'F;'=
@r2855
CGCTGTNTGGTCAGGTACGCATTACAGGTGATCCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGC
+
=8B1;@#>=H4FE69)HC%HF<0%12+>A$4%<F@9'=D079)7?+&;>&+35<GF5:1/64)14$&C$//9<G4*G#H%G=:BCA+C'$%!BH?3=*H&(&#>!=0H%%!0!"24D9C
@r2856
GCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCCTCCCAGTAACGCGCCCGCGCTTC
+
6(=11:E"(@1/6(%$@#0E4*5'2,.@8F6AHB0'/G.B5=:H,H<9:$4%!7,=%)6<*)4AF:1.&!::B>72,D"7-@$?<!$1AC!:;@>?6D=-89:'86<E6>B!F1
@r2857
TCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCNTGCGCAGATTCCAGATGTCGTNTGCTTTCTTATACGCAGCCTCTGGCTTAATCAGCANCTCCTGCGCGGTATCAGGACGACCAATATCCTGCACCGCATCCCACATGGATTTGAATNCCCGCGCANTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGC
+
,6>HCH>@821%9B<E<07D4(/?68&10.-30(GG@7&<G@/"9<(534E;?,0-/GHC@#!/H>:'53(0<G&;354@C6:&E<A9G2;0?%?!<),D#%;,E:/'BH(!@A+&D7B+,5;88?#<D95,!F(,!F,.H,5"D/9.,'D*H%!!21D29F>/1?++@&>CF5'5H.84,0'>$.39/A*$-CA9&G815*HF>?*7(&#2)1;/BA%C7'&3=/95./</%7E*35#G=?$*35?%+;-1;F9>3#<2
@r2858
CAAGNACTANGGCTANGNTACNNCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTC
+
$(!!)(&*"""""'%"#!)('"$)$+$%%"(($*'$+%%$+!$)%(#&'#*+(($%'$*##)#(*#&!%&*'!*&"'!$$)#*!$&*!+))#"#%)!$+$&**$+#!(!
@r2859
TCGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGNTGTAT
+
&(%+"*$#&"#$*)**'(!)&)%%)+*)%#+&"%*'!&&)&'+""$(*)$"$+!&!%+%(!*%&+%**!$&(
@r2860
TGCCNGANAAGNTGCCAATGTGCCAATCGCGGGGGGTTTTNGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGACGCACA
+
"'#$""(!"+$*&$!+')"$&*(&**"'(&%('$"#%)$(*!(&"+$&!("$&&+*)!)($$&(+'+*($!'#('&)*$#*&*!++&!+(!#$&(#!$)*'!#+*'
@r2861
CGGATAAATCCNGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAG
+
8&%#1E5(>>,A=3:6D#$;)3:4EG09<A<6=;1-:A*%*8<,-D'D4D1$9A:#$7:1?(%3AF8>BB*"5E)/7*C0)EC6;(/$=$:
@r2862
TCNNTTAGNNCGTCCGNNCCTTNTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAANACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTATGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGN
+
'*&#*'""#$*&%&!&"$++&(")$'*&)#!)*'*%)%#%!(+$')$+*#*#)&+("('+'!(((+#+%)#+(#+#''!%''#*$#!!(&""+%'*(%"!'$%("*'%!*'#!'*(%($"$#%*'$#%(#!*+!&$())$#'($"&"&$+"&%!"")+'+("!&**$'"!&!)%)((#)))'*"&!%&$)(!%)
@r2863
NCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGT
+
#1=&EB7B)@;/G*5=!,+:2=:*B;49"F'1)%E.+:B!4
@r2864
TCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAG
+
9A,+8@4D7209'""+F5;#2139=?4F*@6.*275!-<$B&E6>/-*%B)42?&9G
@r2865
GAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGC
+
HF$"#%*F?-)(.38EA.GA=+"1F!+:(B%62<<3,,&=42'-205>#%=CF!7)B+H%3>3($&5)9C="'*EF"0!H'%:%$34B=
@r2866
AGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACANCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCA
+
D>/-!<G."'2?35#+6-4)!$C,#<!D)GH)G!?==F?7:E>,5"!/8+!<G2+"/$2+B6.5-+=C(!/7.=3.,+%3E"EG;?$E2$;?4<A;'3?H!-/?GG"A0A8/'0D?*H1?2'+"2/
@r2867
TTATCGGAACTGAACGAATACTTTTTTTATGAGGAGGGCTGTTTT
+
&0/4-08677#;$:')#><);+BE-='/$(*A43H?7:D.%<=&.
@r2868
AGAAGCAATAAATATTATCCGTCCCGATATTGAGACATTCGGTGAGAACTTA
+
HF<,(E(B<);B;?D.&1%3(G")+3BE=;:51<:7/,60*!*G%>+.)A4A
@r2869
ATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACNAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGCATTATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTC
+
,?-5AG2'(#!.;8*37FC/5<189:$")(#A8ACDC(?!?5:)8<'5,E--B3<+5.?,#4)*:H#""5C9C-:,C8-C*%4AH*9>!-16"),E)@"-)>5=6%&'8C,7.&%0(G:D*'!E'79*--'*AG#(CF2@2H'259E(*H-:%58&'*=<.DE";D!C63G-4?@;@@*#5*HEHD;('"-7D"=A=94>
@r2870
GCATGCCTTTGGCTGTACCAGNCGGGGGCAGGCACACCGCACCGGGCTGTGGCTGATT
+
###14CA'"6E:798.+*A#+1<F*?;.7F("7)#*"H'5.H>?(H7AD7CF<.B-/8
@r2871
NCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGAAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATT
+
"A?:82*DD$5)7.0:"?'7E,@AC1G:4+%%G'8826A?5/G"%0G$(GG/@/:GBA*:@$/")#28$F.2D6"59$51/$6*6%5+)$.8.%0&"53DH5:+:FA86=FH$@=&E*''8@:&D
@r2872
TTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATAT
+
:<</H=/./)D.+>7<4FD?@-C(",)7G7B@A:(2C!C==;$G'9
@r2873
AATGCTGTATTAATCATGCTGGCGCAACATGCTNTGCTTATAGCAATTTCAAGCGACTTAAATACATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCCGGAATATTTGATT
+
'&.1#=))/)-34+#C>>F=/-C%7:HF?CHE!;%9/F:AF)A*$9%"CBG;'1<B&1&BF>55?198?+%2)0:)?2:30E!F;%:.'!.$'(=;=&<@>)$<9*;9)18/5&96'54@56&D8%!",&&26*/E&'4DF/*+,*2)(F'1E42>*+@9@61*,,=7C7%40H)();7,(6?&
@r2874
ANGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTG
+
&+'$"#$("(&++$&)+)+&$*%$"&*'+&%()+()%+$+
@r2875
NATGCACAAACACGCCGCCGCGAANGTCGCGCAGAGAAACAGGCNCAATGGAAAGCAGCAAATCCCCTGTTNGTTGGGGTAAGCGCAAAACCAGTTAA
+
1/%?.@6A/C9&B7<=$.@!C744?2H'&#DB'A2+'>7-:%%G57>'"#0/?C$6&H71:!?"0B29'"7D'C2(.F6#94@&5&>:?&5#=DF0,<
@r2876
TCATAAAACAATTTAGTGAATTTATCNTCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTC
+
;$--+G#8@>=5/18C0+"7@(7F8<D?BHDA0B(,)2.'4;EGHEH@H??4/6)5BG%(4?,4$H'?
@r2877
CATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGACAGTTTCGATTACGGCACCAAATCGACGNATAACACGGGGGCTCATGCTCACAGTCTGAGC
+
=>DB:"2$($D.CE3/B02(;11/3F/H,B5F="!(H4&=7H<<<9"/5@%=+.<1+,$,)G'>A5@G95$&31=1>06"7#1<$&67+&0+D.B<C$=@4!H=@FH3FB*B3>%#B21D@@!)%
@r2878
TGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTT
+
387>.GDECH/.?=2+"=:G05>3$<%-=,1<@E(!'2,%8C4%8:<;4!.#(7?8&;-(A%=.F/-:A6@:9@!>C7?#%>C=)#2>-/*F$#D:,4B>-FG3(00+$,!5F=1=%@;9=+$8:9#6C,-$C<D0'786#($
@r2879
GCGCGTCACTACCANCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGG
+
4<CE"3)=+3B<<>G?.52&3@/".$ED#.=CHB3F;A666/:E(-";F
@r2880
TGACCATACCGTACAGGTTAGAAACCGTCAGCGNGGGGCGCGTACTAGTGCCTTTGCCATTCAG
+
!<CH4EH(?0/A5&ADEH=#F$?$!.D*/G%2&57+HA58#+'F13&(3D82'B:1D"E2+2&+
@r2881
CCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGG
+
H9'48+9"-2"F,7!:'0(4.+93';3,6;0DC;,B7"ABCB%FA<'"
@r2882
ATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACA
+
?5'<(#../1E?%0-(>,2=G'>?940D2D73GH0(;3'<&;5.>=;75HB#?$A)7:@&B*
@r2883
CCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGC
+
!;>></5>=.(7(&/B8+4;A>*=B%)"*0-6<"49GG';08#C0;</:2F*><&@.FE?G-B?'6$E)*B-;0+(2EG42?DE
@r2884
TTTATAAATGTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGN
+
*:''D%03GD=>&)#6&B96$,GD&C!#3!$+<C2C#@!"!0D;DA<=%#0'H8$-
@r2885
TGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTT
+
1()#DEC$82%>&6B.?(A'!*-#@,?;*7B40>'7H-/A#+&BE6C
@r2886
TGTCATGCCGGTATGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTACACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACG
+
-/84*1-4A-9B77?='48DD./$05D&0A>8F7>7>*B#=!B%B.AB:B1<?;EB-..):":.5;64;FG$(62>@EG-&,-8376FCH:GC03)@FG9,(5$#27%+=&5.EE,*<7)=!?="2<,%F9D"0@GB)"@<
@r2887
GTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATCTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGA
+
%F6G,3!E!=C?'"/@;?/%G%6*8@3@-H?2E%?'03'G$*D&'>C#<A)7@@D59+F>%#.>-'CF)8/@H2CE;'+3DBA*9+70E'BD%!:8;@=EE.8$&!',>2;?+%A&<H%"#*76E2A!%=&-=7"A:$E$9)@GA4:4;;-!<;";=7%=A$G(6@B&.'8:<+A(@*"*99"#;G)DEA
@r2888
GCACTGACAGATTAAAACTCGTTCCCTTCACCAAATANTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGG
+
*3E;:6#%-,>&7)+B91,G:=)=0,(:<>6=271;3,F980/6F>.-%7,B>C,BF*&=G;G,4:=*G@,;3"B62G(GF:)&G+&0##=0--&:7B9A18!"A/)$H)//58@+;:HA=#/8C8(@%D@+:D&:E*F@:8H8#"=1"-B&;D?7@D&/)-
@r2889
TATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATNGATTTTATATGAATATACAAATAATTGGAGCCAACCTG
+
=&03C3F/01#6>.;/24#=D'#'/8G(H&(3?(F0(4(7$(3H3*6%27-F1A0--49E)H15-5=<?E'"7-<&>).H';@><H+3G4/?$<FG652CG.;B(55:+2F%F)<;A(.D5=*
@r2890
CGGCGCAGAAGGGCATCGCCATGTACCGGGCGATGTTATTGAAATCTG
+
*7D96?6/H7)D=/F!C:G7EH8G742$A,7A!+*@!?>H,C"?@E%1
@r2891
AACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAANGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGT
+
@+9?-551,-;>?5"&68.G1A!BF-<$DGD)A+7,G22/E#G':7,9/92D0';*"!0=<0%.AH*F$>#1;<632D6@-=FA0=;+7(+!B>,4C/?+%5A:/+$0
@r2892
TGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATA
+
2+7"EG)=*2&,6CD#G<8F).A?6A=H6:>B!8>>H(3F6-,+90!:.6E/:2#*E:2C/G%*;#H"30A&+818?*G*73
@r2893
NCGGCGCCTGTTGATTTGAGTTTTAGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCNGTAAATNGCTCTCCGCCTACAATGACCTCATAACCATGATTT
+
#+%$!%&*('"()+$'+&#)+'+&!!'$*$&'*)+"$!#)"*%)$+++&'"#'('(#&%((!*)""+)%"'&*#%$"'(#&#"(+#+%)#%#)#%'#&!'%''&$%+"
@r2894
TGTNCGANTNGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAAC
+
&'!#!**"("$+!+&'$")&&*"+'+$%'#*#$$('))&##+"+%!'''(&'*
@r2895
GAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGNCTGCCGTAC
+
+4#+57EF4F-G&+!2<1@CD@!6!04DH)1B5D>!,;"86%80*B(-E=<(#=$?F76>?(!3.1$C6(&0>;%BBA).8##5/
@r2896
TTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGAC
+
6@(!E2(9*E+G1#;/H%=<+-$E)G'C3+%2=:-22A.,%
@r2897
GTTTCATCCATTACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCG
+
%1*"5/+7G%F15@45,8=,$2&#.A533@6AFH?4=7$*?GA*/=78@,'8@@E1G0=E-$F7+*'@&0:9"CDA)@C.!9"@G)C>!D(.523':@G.F=8).(F8&C."5/!:5AG
@r2898
GTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGA
+
2%?H/C&..),A!8E',&&;!(6DD>GFH':<+@;#8?2!.)8&=$;(4?)'&'B(<87D0C@8=,FD3%46EF0"7C:D9?<%)%2D;<7>75E<=74,;F9EA.'3HB",.H.1;-H50?F</CC&<;?=F'A-%*)#;)&&?3+5@*@B<)D)7HBE1!*EF*0-9#293&."E@-7>3BA$85E<3(;18D,5BDA"?DC+'.0G*47+@D29
@r2899
TTGCGACCATNCNNAAGATCCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATA
+
%"')$)!#$#"*%!"(('!++$%"*(')&(%&&$+#+*(&'"&"''"*!'+'+'!$$)))+'#$&)&&!*$%(!
@r2900
TCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCC
+
2%-!7564'"HH3F.;93F3FC;E/AF69H4"<7C5%(G1ECG7%=6'28!C
@r2901
NGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGNGTACGGCAGACGCGAAGAAATCAGCCGGCG
+
(E@,?'78*"*26$*)H169*7@$6!:$54:CH<F":7.1D8G=$5/(1*=75&:#@B91B'5;88E<$4F2.,E9%#1.'3G'=
@r2902
NACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGA
+
$8A""6>!3<'):)(D)!DF1H,;BC($/84$DA234&"</EBA((F:'+.$F++HE8</:$"(2+?.0@FF?-CA7+49&8C/%=HED8+50A:H3;0.AA."$+;-+8/."*9H@D3B21,'1.)>E(6G:><><D>+C,E@!6)1A2D+GH=.&8
@r2903
CCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTT
+
H<*'0.A;8&@3,DDGH6A.FF<F)%@'36$5G$-E.1,3"'0<+HA'(F)5&85>D/-3B==AHCH)/$(&!-:
@r2904
CATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCNTTGTTGATATTGCTTANGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCA
+
.%"1/BF$/H:&15G-C/="+DB"'($*&%,C.2(@3D6C:AF*9E5H4"?F9/?'F%/(!FF6/(&<'6!$2=.2'8+&6!"9E8:HDA,&?(&#H/D7BG09%&;8,(9?H'F@;>=>5(04G#&+$"4/8*H@A>()2GC?#
@r2905
CAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTT
+
:4G3/-=H+9'F!D-DA!=7B+$A,CED9CC/#2,*$7H>62FDH4A08E58HB,';)HG>((G1--3@'G&20+>?C$01
@r2906
NCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAANGCCGTGGTCANCGGCACCGCCATCGGGNTTTTCA
+
##,+/$<05'+13E)<D0,2'D@G2F#1-2D,;=-,%;,E&!GE,%;DH8?44=9(E<A>C3:!!@@!?9H1)E)-1/)?6>@;)&#'3$<1H!.+7>FA79G.+G"?=B%+9/
@r2907
NCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGNGCATGTGCACCGGCACTCACGGCTGTACCGGACTATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATATACTTCCTGTAATGGTTGCTGTTCCANACTGA
+
"+*GH<($@'%C2C:,ED#1?2$FB45>+3.&@B*A.@(;B$",?2238A!<E5*%4:@&E27;2*!#6*B+,#%3F*5.6*=H>::E5E@.$!)F((8>6!&%;($3/D)6;<6382?.@F6)B1>E9H)/H7!%1=;0=?76E)H!!3(0)2*'3@*9G5?&;3-FD9B@<%69.;E$F.0G2%'4DC!4!4GB,?5+(+-..@#%-2>*0A.5"5.##F$#@45A23-.;+B*1%,,4+@-6&:!,3?)9<
@r2908
AATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCNCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTNTATAGCTNACAATAATTGCATGAGTTGCCCATC
+
%+&-10+!+=;8H68/$+C8G@<B+3D0:3@ED$(@2<.6#@!!*!-:4)$)ED-+%ED3*$5:)H38&D,-E=&1<'(?&.A$B&578-/9F0B5=%-;7(9">!--"'50-<;)<"B,&4,D':
@r2909
ATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGNCGTGCTGACGTCCC
+
A1*8@-$H?%C#*'1:<72*;0E0C:AB:0#'6*0GDC4&7?1G)?%'+FA-A':3%"D/3,:8
@r2910
GTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGNTTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCNCATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTT
+
=3-7,3&$*#7G2:+!H*B$4+D<,+'+4>:'3,-",*=>,($09A3!/?(E2>H++@""A&BB?+",1,26CH0+?8H:5/9G*G&BG0'*=)715':('9F3@>8-GHAE$@-A5=B1?%6*%=)A74EC#'!+#4'-F*A($7;+"192.(%B=@DA7$>*<+;A%1/5.<:/*=+AB>+&"@:&?(8('65?#>&&%::H0G(+2@C,(#-?C6BC%+*E1*FA-250E'7-"*&:H,&7A2*D"7/H.@B;4';2
@r2911
NCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAGACAGTTCTG
+
%C2>>D38)AC$%B*:'9>#2";.B&*9H0@0=-=B3;>,A0(?:,'(HE/>9?E*2.D52>,5D'6A/6:@4284>1+':<#A!EHA4-1A11A4)@7*"?2"#$;<
@r2912
CTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAANGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATT
+
;;?>0$'D5@=!6,A0:$&?5@1H:%<D<?B>%D>3)06#8-D0>HAD7$4@5%3)(:#**?1&!;*16.D9+>5@'&*!:?A-AA"!F
@r2913
TGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCGGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTNAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAG
+
8<">H6"/HF+-H(4%;D<D&:=@8339:0-$'#&9444/)6E&:)%'68AG*D6E*:'@:3E#@G.&'&HB3!50+0#9A/C!H;>@0/E)':@G%.,8AAB04>C(E="@7.'&)/,-C;38!5=C4&8</35C!A>&"*')"6.DB1!>"&@@.33E-7#E4!B#*=4%D(F.%+"!+E<08?G"334#+F&)ED$1,%6%B*=H7#
@r2914
TTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTNATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCGGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTACATGCCGACACCNTCTGCGAAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACG
+
+!"#*+%(*')**!*"$$(()&***'+!&&!#"&#!+"*%((&%!%%+*(")+%$+(&&$$"$*()'%*$%#!+%("#!!'#)$$"(#&***$"+%#"+!*#("'&"$%($#"$&"+"+"+**$&#$+!$%#!!+*+!"#%"(&'*++")+)"'#$&&")*!(#*')&'!'!()%&!+)+#"!!!$!$+*!*'**$$#%'!$#+&!('!*%)(+%)#'(#"%)!&'$!&&"#+(")%)($$"%('(&&&($)'*#&&#+%
@r2915
AGNTGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGG
+
()&+(%)+()!'&+*+%$)+!%"(("!*'(%%#!''+!#)&%(#+#!)&!&*"*'"'*)'&%#+%&$(!+"%!!)*$*((+&#()*&+((
@r2916
GCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAG
+
A4-$((7@%:&1#-?&6)G6H.&7/&E:',=3;E1D?F2@'C?<C"3@0$8E06%'';787DGH:6E%'%/@'%4=-<D'+/#+12$#E!@00+A+@3E-9"9E:?*B8H+6+
@r2917
GCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGC
+
DE**>H>?"G(=@D<@90G>#D%%.A0>)H6>5F7H1*)2&
@r2918
GTCACGGTGGTGTTNCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGG
+
-%&8(E%*.361$C,4;@1@#CB%$64=A$G.EHF88EB/7;7@*:=0,A(8<;D0)6+7;FA6C
@r2919
AATACTCACGCTGCTCGTTGAGTTTTGATTTTGCNGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCA
+
<3D17:/%/>BF986G$!(+@A76.:3%BA&;C4=?9)6$(+F)'<F?56(!BC9"0@20GH,,<F*8087<')
@r2920
TTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGG
+
8$H"*@9@66DE#":AH=0()>!1E.0-:#"(D9E#CD>>'E
@r2921
TGAGTGCGGTTTTACCGCATACAAATAACGCTTCACTCGAGGCGTTTTTCGTTATG
+
H-1,8'A0:..@'B>1$+?/>-?1/8"%-)3&%!'H4D'((.!&1(0,F:.EAC2E
@r2922
TTCANGCACTCCCCGCCGNCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTC
+
*(%""'$+)+(&+'%'!*%))"$$(+$"'"&%++($"%$&$*$#)"($#!%)%"*$$(!+!(%)"*$'%!)*+('(**'"(+$#)*#*(
@r2923
TAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCA
+
C>0+.4)8C%;2;>28BB<3/0+=18?/<=B!%F#@D)""78C9:G!!1#12>(D7G2",.:)6.;A)4,:>@23-1E(9*@CH)A=FDG/#8%'$#6H+638;0:&=</1>#F=;
@r2924
GCACTGCTCAATGCGNCAGCGGCTGATCACCTCCTGCTCCGGATCGGNGTAACTGTTTCCGTTGANGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCGATTGCCATTCA
+
@GCF=A(<3#0B1#1&17(.D@9.$$7+,+BD+"D&7!-=+&8E$3+(:"7F+9-+4+G5?G$8:H0<0=24)!*C$,'+4F*A%%2E;(;")&@<=F>3D5!=G(8+FD3+.%7-=:5)1)5G-@9;&(3C,$D#4%E<%-&/7#=30"4:766642<>47.@,5G+;$-0+C#5*<B/$H?.B(.4A.C@5G6E'/5$8#>3*=8:D7%,*+2DD+
@r2925
ANTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTNGTAATAGCGCAGCTCT
+
#!'+%*'#"&%!$$$$"%(((!!!&+(&'%'*#%$)($+!#+)#'"'%!*##(%&*$+)&*#("*!")!&+"!#&*))"%!*!
@r2926
GAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTAGATTGCCGTCGTTGTCGGGCGGGGATNCCGGTGTNAGTCATCTGAAAGGGATTAACGTGAAGTACCTTTATNAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGA
+
'*$+&*((!)$++(!&(!%'&))#%'!&#('*!!"(&&#&"$$$'#)#$$!+&&#!+#"!%%$+#+%%"&!&!$"!!"%""*)'*(&+"#'%!)'%"'"$%!&(%&!%")*"(&%'(+)'&!'+'(&!''')%'%!%!""&$++$%+)&#'$)&!!(!!!&"))%')(!++*"(&#&%"&*%&''&*&*#)($(%#$)+!%(")&))(#)#))'!*$&')(!!#"()!++"(%&!"$&$"'%*"
@r2927
GGAGCTGCATATCGAAGTTTTCCTGCCTGCTCNGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCG
+
>:<#9><&@?0>B(,9-E0'!!0!,D-G<:&=H;'*1GC.D>0,4C1"7-?$?.*:D#3++#(B($4@/=>%B0-7$":%+'8.2BA7;(2+C<GE=5<7E89+/ED%6/3C).5/=,+7$><(,4.8+<:@&88';G*"0+>&.19F7'=H?
@r2928
CGATTAAAAAATCTGTCAGATCGGATGTGGTCGGTCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCCGCGAGGCTGTT
+
(7#@&F;(@:!90<(D33G13G,*&EG%*<DE">%=4(9'E$,##0%=',,,:+3D,,<$6!6>A)1&.%BG94/-,G)*(-/#,F-?=H8B&C&;,""E%.-8G<$>#/!*D;A.+#-,50G=
@r2929
GAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGTAGCGGCAGAGNAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGNTGGAACTGCTGGATGAACGGGNAAGAAACCAGCAATACAGCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGNAAACTGCGTGTTGAGCTTGAAACAGCA
+
$74,7;B/D)%DH,<-8/46>A%->#'G!A#7C#@*03%16&+>@G6+">H<9?<F**&#DC)3):1654/-E%)$A((8,3F!)*<DB2!53!D3<<:-F,-B(+!>-,46D85E%73<:.'C.5.5G<-1,'<6B*H)C.G8=/@/GH8D8.8B1)$=2@@B/G&96:$,77H%.C>F'$F@#69)*D;#61B+A,#C%:7)!BE:,E>4)<C@/+811'.HC;.%
@r2930
AATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAAT
+
HE;"2;'?*1407C"-'5+0FG'38@-E#HBD>C%A;'B*F3:G(&)C?2>A-+,/*?)@9>!?&4CC0+3-,F->7.%<(
@r2931
TATCGACTCAATGCNCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACC
+
>1FE3@3?-&;%@/:((E@6;+(")2/7'%H0=!/'2&.$*2*02+7-47/
@r2932
NNNCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCAN
+
*!!&%+%#*#*#(''*'#"(#*'!!%!&)*&+%!$'%)!%#+)+&)$!!%$!!)!'*&$!*($%!+%!#(+*%'($&)!(+&#%*%"'#$*$'#(*"#')+"')+'"
@r2933
CCACGCCTTACGCNGTGTGGTCACGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCCGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCA
+
A50@+?C9/=F=;52)E;3+(+4942G=6!(+7/!5E>F-3;@7DA,:*5E*!".57H3D1)1F+1B!#H?5'7=H7?F125%?*$;&#;*%($46DG=.'5*E5#@&377&!D4CH4B318
@r2934
NGNCGTNAANCNTNACNNTTGCCAGGCTTAAATGAGTCGGGGTGAATCCCATCAGCGTTACCG
+
#$$&"()#(!&!(!!)"'%"*%+*#$""$'#&&&'&%+%!%"!*+)'!#$%+'#$""&(+(+!
@r2935
CCCGTTACCCGAAAAACCGGGTGACCACCGGCGATACGGCGCGTGAGTTCACCATGANTCAGTCAGCACCGCTGATGCT
+
5C49)2G+B9&C,?5H'.FHC45'*'-$4&07?:/(3#4=D>9'C.$8&+)-0=>>0!HC%=/&=FF'1*9A-7-0'F1
@r2936
CCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTNCGGCACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAACCAGCCGCGCTGNATGAACTGATACCGGGGTAGCTGAGTGAATATATCGAA
+
0.,39?@7?,17,2!++9-)=1!H=CF9D!2C3:F@=C!3E(-4*E'H4H;.*;"FB9B8:@*+B+H@"9E.."F*-15'G5:GC?;59#HE&/=#?0F:.5*.8*5!,0G(*+5&E624:()@C"8%.F,9';,@<%H)*C:;/=5A(*GG*;C*7D
@r2937
AGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCNCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGA
+
8H8.7E*C8H/1)402B:!*&?C$,;E+4?'F'!<B'#<;#4H*G@'3+9"G?$.%#+6;&B@2,$!0>A@.5(8E*2.11-/4BG2
@r2938
AAGCGGAGAACATCAACGNCTGGTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAA
+
,:0"@094!=?6=C"HD2>22$5/FA)-?%A002?1+*&3E,0%)1B!%5?H!%*&<!=0$@$(D4DEA91@56(%*D,E>+G40E+22G;>)&
@r2939
ATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATANTTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCA
+
@;0<!D3D3=09>8")9"+8,9G!A/=%8A@EC'H:*7";+A1&B,A=48(!7-6,#?(=,"@A=5;,'H.B-*F7(.$)72*31%,5A4:H0E$1%>:$B("14HD!)G7?<!AE(B2((E<"57867B662'*%>F75'3%H&F%AG2#D/A8@'3%2#(132+E;(+5H@<D;D*HEB#
@r2940
CCGGCGCTGCATACANGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCNGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATG
+
A)3$8(*7E*>6;&C;0!'!=7.@9BD>-(1+3D3:/!9)H/%-0=@6>1-7!;F92/#5-63E<71:7A,*=.7A*0>:("E4B<03'6:AE/487=5'FH=(<.4*$<3A(C**:()$*'1%H"!&.46%5(2AHE&,3"%0<96'0.%(844=!/%>A,:;+2-FHEHH+8;?.%@(HH9%<"56$E#.
@r2941
TGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTT
+
80F#(+-HD$<1*=F&@4C%19&"$9+>#E7DF!H:<7*G5@@/"&E7.'>->H2;##/:37*!=H'6AE;9,A73F/6,3G!
@r2942
ATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTNGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCT
+
H20H=)'C/@+&=(>A3'H:H@,@/#3D%D;B739<?H';;6%ADG#G1%%+@$@F7CE$$3"#+,%&,2#**544%8+HGF;'&2**@?@FE(/6!"FFFD2,3&5%
@r2943
CATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCAT
+
E!1F1!,-EB!@:&-'!E3=CG?3#1C4>.<G.(8A7#<<4@A
@r2944
CCGCGACATAATGTTTGCCGTNTTTGGTCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAAATCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGA
+
6B8(@*/G7E0E&D0**&F*4'G67(0:F#93(C$34-$%B61B=99;'/6D)2;GB!&H":@F&F%!D=0&<3!1D*2+$2E%EH!='!=($F2A51F69=F7(05?+G8/<*1D74+'?$8:/"*2396=G(2#4-(6)E;C,1/
@r2945
GCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCC
+
1E%BDDG"72<"-7;5#+=;,&(),E7!+4/'!77@=2BE?,3H5
@r2946
TCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAA
+
*+#"""%*$#$&+(%%&(#+*+$!$(!++$)!&&+'(%"!%#!%**!!&$''('*)'"!#)&&(&((!$(()"&%"#
@r2947
NANTNCCTTNCNAACTCGGAAGATTTTTTCAGAGGGATCTAGAATNTGATGAAAGATAGAAAATTACGACGCTTATCGNAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCANGTCATTGGCAACAGTGGCATGCTCCGAGAAGGACGTTTGTAATGTCCGCTCCG
+
&(*$"'%(&')#*+!"#*%++!*$&$+""$$)#+(&"#$&+*+$"*'(&!+!''")($+$&&%!%*'#'&'&%"#+""%*$+")$%)#($$(*+%+*!(+#%&+'%%+$$$))*(%%)+("$##'!%'(#'')&)&"!$&(#"!$+!%*%&'&%(#+%!##%$'##)#&"%)'''"""+*$+'!"()&)*!%)+''")+(%+)+#+#!#')
@r2948
AGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTAT
+
-:EA)B@?*,")2<;37<.43B#:4#2DA;;;'/?7;/6<BG*062#+#!9E4<;:C4H:+7);,G;38??>@8/A2>:42->7A>;C?GDD"2@>>-DA+<G""4G>F58,=
@r2949
CGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGANTGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATNGGAACGTCAGCCACCATTAC
+
E#:556(?::GG14?+%C&H*C0!(93=1.A#)@E0D&.960$/=?$9':+:A(/?B8=9&#$!0C@#8558@?EH:/?,F9,D=!C2"B,,?.0>%9($D526@/GC>"7*:7A%8>)F3??269<#HH==A$/&1*=914=.E5H@)40B5F;+8-BC>%7?H
@r2950
GCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAG
+
#GH*!AA)E?F:(*2D+'7HA(780/"3(-G47C=A/<4(>(?/>HH#<<$8%3?
@r2951
GAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTAAACTAAA
+
78>/1G3,B3@BA-:>ADH$*H#-#"G%7-2C-*'50DA;*'.=C1,7*F$@9#D*!&C.."*'8/;04;1%CC8&@$BFH08!@"H?)*%,>&4!76.6B07E@-%?$DG((D0A%B=HD6C1))#8?>0F5$25+$
@r2952
TCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGC
+
/)H6-$1>'=F&@G+'=+:-DHD-22(%?95D*<3&5@(B9E=!/A408')@:)%'A:G9!!/,F))+%0B@'%H9,#$+-.('2:6!0:%)$D3E"
@r2953
TNTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCNGTTCNTGCCAGTTCTGAATGGTACG
+
&"++!(($"(!'$(+"*%*%!#+%*&)$'#"!++!(*+&+%$&*&!%*)&("'+))'"$%#$*"*&)"'($*#(&+)%!$&%#+)(**)$!%(#!
@r2954
GCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATT
+
@-9*H<3D#&'#CH%)1(>1<<1@+-0,:$BAA0BE-4-*A@(0*723$4-7F1
@r2955
NCCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGC
+
$9E80.B!@(4!1A')-=E0/A!@;>AD@#1+47;B<C*&&*3@7*B;FA8/-D!
@r2956
GGGTGTTGCGCTGCTTATGCTCTGTAAAGTAGGCATAAACGCCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCA
+
:9$,;<BC)&;,#&&&1+E-,<&/C-@$*)E=9"?B)<0A3+<,4>B<E%1@-D;/,6!$>HB)/H0</G51F4$"?84<+E#3
@r2957
TGTNNNTNTCNACNANNTGGCNCGATTGGCGCGACAAGTTGCTGCGATTTTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGT
+
!%'"!"*"($!"($*#%%&%$%+)(#+%!($!'+'#%*"+#)*(")&&)()%#!*&%*"+$*#&*$'!+$&%%*+'*#!(%&&+(%!*&&*&#'(!(")(&#*$$&($)("!++'*#)
@r2958
TCCAGTACCGCGAACTGACTCTCCGCCNTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCG
+
9"'H?*7;&!/)D3E$HHCE?8E)EC9/=F-:(+3*AD,-4&'&FE6'7D#G)8@.F"FC8E@(:";9:F0)
@r2959
CGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATNTCTNGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGNTTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCC
+
,)&<>.5<0(:4860%D*G'1A>,@0F.D,!@GD:(C6F.(59&63E/FABG"/(BD3&376->"4,-A@-3-'->H63*CE,C;'2G@'F>B3H3-80(!">@@2C/.9$F4B*H1%6F5<*585;1&2<$A=)>@4$#85C6.35&:)?C(2/D@9G1BG(<:%6H;#&D<!??A2E#3DE8C"!+6,1F+-=<8-8E/%%-=,9.-3%4""%/"9B>3.@.$8!'G./5:;3/"H+%@87'#%;6&./1A:D0)-!00#
@r2960
TCGATGACATTTGCCGTAGCGTACTGAAGAAGCANCGCGAAACGGTAACGCTGATGGGATTCACACCGACNCATTTAAGC
+
D,26%7,52)/3:-@$HHGH!:EH2A?C?AA1HH0'*$&'?!':CCD:;(363(732*7F5(.?D/<B;.#":3":5@HB
@r2961
ATTGCCGCCGCTTCTGCCGCACTTTNGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGNCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCG
+
G%2/02&:1.=C=378B>"5E26(A4)-"!86HGG+=AC,6-EA-,0"B)$*=$>:%4<::#?%2&"H+>0,H.$+D%&DD<2=*(9.+706/D*)+:$"#<B&&,E>F(3D+953"$#2"=-C,D7%,HHCC-'=)D./#7,A&"1.#-#F;1=C%-:9B5/8H8:E+
@r2962
TTCCCTGCCTGATCAGNATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGC
+
*$!*%'*))&((('$)+"%)$#(*$(++!#+&$''"#""+!(*)$*)"&"#)*$#&**%!&%*!"#)+
@r2963
TAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAANTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGANTCGTTCAAGTAAAGATTCGGAAGGGCANCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTTCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTNTTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCANATCATCT
+
;'=D"&"G*4F$)">G54=#"8GGC3)F"6):6(C<0?5!:4-))5F@+,1+)7+&/7C$@-=9-**"&BDB.6!D@;;3<EH;<"EBH/'FE(&=E,1('1&A%51H61C)0@E#?:.4!?.3E37%$979-A?)?;"><)%C%!C39=23-#A6A6FEEF;<,'*A4:<7,>&,(5=D9B$.>G8:-;5G<40%CB'%+0B63>;C7=+6!;5)$1>1:&9DA@G6A=6FA%B1=?>*"D?%<3>?:F0#%9%F@.G$F4"A0+)/0#'.C&<5'3C%FH>?;@5
@r2964
CTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATA
+
HG0@?1B->7"9#&#(.<F;=.D?GA4A:70$=>139G4%"@#CH&.?0E5:HAE/0?0,.?)<62D7G<@13=+19H>F5./"**.8':F9#F'@@%82,FB>)#81BD@))E
@r2965
CGTGATTCTGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCT
+
:/6.E;"6&+$7#3F#>*+G">F)?6'48"A/:/1'A8'?H)8)($-AE5E:8B3>3=+=='"?.H)"/'!E
@r2966
NCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTC
+
,>5%650@'::*(?=/@?E:&,@4*8F<&848(/ED--:*6-=G8BC*3*5/C;-0(52%'*'57,6GDF(F<HE;=
@r2967
CAACTATCTGATGCAATTNGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATTG
+
D;=C5;0FB=,A012E&D>7@6"4-2"-$D<B!)F(94A5&A<"!?5:#GD(-2D1;@>G@D.,H--?5=;5?#)2$BG622A'D6B+D=H1/4,,E?2B*G:H2HA06C>3<2/'.H:H)3%
@r2968
TGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATT
+
3.E5&C*!2#52$,+4/-.B&'/3&3H*,,$(811/>:D*4'=
@r2969
ATCCTGAATGTAATAAGCGTTCATGGCTGAACTCNTGAAATAGNTGTGAAAATATCGCNCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGG
+
"+4!%D>&:?F<-C%GAA8C.79F.FA8&6<8-2#F*2@E$1=D=H:08,B8F3E04'>2(D:'0%;F'B4")945F-$!?%095C-D4E4@+&9
@r2970
TCAAGTTCAAGCGAAATAATTCAGGGTCAAAATNTGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATAT
+
,'$FE;"8%.%-D>0="?E9EC:54D;'-F"(7DH.(*EE-80C6B4:6>E',"60$*/;F(;(76=>,C'/H$'H,9E"%<#2*=?B)"<><E)8*+A*;>$,5,A5%&<H*3@@D75D#3H)C1</(<:H?B5&=D%/G2C4B:F
@r2971
CAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCNGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCCGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCNGCGCTGGATGAACTG
+
9=9*6G%:+<E:D*5'"GHEG*3D,5G!H:H;F*@;3$!5B+"2+7$3;<0C7=3D/#&1<;@6'/8<*@GD90.#6(4##B@:B3'4&H2HH1"?9BA"*./55<3D;$+49.0AF.:@8%+5B;"$%.!H4@G':&.ECB,G0=)34#5@A3#!&9;<1,8C/.B+E0"8*D0>(F5=6('?B'F=22'($-E"3@AH.BD'1?0:4216H/2<
@r2972
GGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATA
+
8:G;)>946E'>C7&&"2EF7EE-H$DD8@<CC8/+(=AC;&5BE9?!?)<=C*H&:;BBC*+DHB*6$/!G.-68/#,0+@@'>
@r2973
AAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGANCAGACTCTGCATATCTTCCG
+
GFC#;2>AE;&41?'CB.%3H3G@8C&B(&G/!>%)@AHDB<!FAA;5:,>*?18%H;0<A9'@,F=D=A4.*-7"+3C
@r2974
CCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGG
+
14!G<?E*BF))?C!6C=?51!.B1C#>7@)5D$<&1=;!'7'3)8>(.?0.,#7G*$*4!C*7,/FE8+'C1-7E2<G@B)1$66C;=(B?18*7E76@A%CD<58A(3H$A&E9D+)E13F(B#$B
@r2975
CTAAAGCTGAAAATGATGCTCGGCGTGATGATGTTGCCGCTGGTCTTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGN
+
95$.!.9)58>0CB@'#&=0,;>$E.08.FBH>A)!"+=*+3!!;6+"74E54<#8!0H+8+7:A@@%C*716C,#4<;DD6$(+B
@r2976
GCCGACGGAAACGGATGGCGCTGTTTTTCCGGNACNTATCATGCTGGNCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCCCGAAGGATAAATGCACCAAATGCCTGAGCNGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGAATCTGGCGCACGCCCGGCGATGTGCGCNAGCGGAGTCGTGCGGCTTCG
+
+=2?.=:FC,2,75##*G4$<;@B&!F$D>9>(9B,DA8CB'F?C90(*%#:G6@"&$+=>B40')HG/,=)$H%G31'<.9>"F1,8/;.;693A*#+@9DD35)0@=*7G?3&D@@6B$0H6.E0G#A0!1."8;:H*2A#06+C94BH03B4+D2@B3)@)$7&-F7C3HA"&(4+3BA&8B+)+>%=HG-/20-=B/0?%%)3)=FH"@H"G9#?*8,;C=;,*!:A'0!$:.*D?+4:CEDA*>3BG)#*%694B9C<C2C2='*.)G0-.3H=.>B;=<0%H-9<$.+F2.>,D>/?F130?)9'G.
@r2977
GAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGA
+
,2D35+/C9FE22*3@'ED)G,$E8%B<7>+!7!7-E,7F
@r2978
CCCATACCTCATTGATTNGNGTGCCCNCGCAGTCCTGTCTGCCCAGGACTCCAGCATGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTNATCAAACCCTTTCGTTGCGGCC
+
&!(**!##!(""!())(&**(**#'(!'+&$"!#!()$&$*!+)&)%"&*'+##&*%'#'!!$%)&'&'&&++$&+'$!&#++&%'+*&'%"!%%!!$'$""()"*!+!)#&
@r2979
GGCATCACCACATTACGGCGGTTATAGGTCCACGTCTTATCCGACGGTCGG
+
H79!);!5<17EC%6%2A-1&?%:,#4>)>?,+:E%7!"#&G;<B@&'$4@
@r2980
NAATNAANTGNCAANNAGTCANATGGAGNCAAGGTATNNCTCGTCAGAATGAATATTATCAAGCA
+
))$%!)"!)$"')&!%")#""#)%$$))#*)##%*"!#!!+('$)($%+"*"*&$$%+""'%(+#
@r2981
CNGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATC
+
$!B.F**'C-60-?1B>E/E,?(AH*3&?D!53'-(>H$9G
@r2982
AATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCNAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGNTNGCATGCTAGATGCTGA
+
<A"D&=B%!$*=<;*2.<9F->+7>7!H.&.322(A+'H--;#80:*F$;,D="?--H(/;03*<2)28+&(##*)-G1+D3?&)*-2F8#2@>'B69F?;5$3GD)63')B-7.+&'2<?"C2G/0G?9>A;*+C6&3(9?&3*BD"2
@r2983
NTTCTGCTTTTAAGACCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGNTNGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAG
+
#A8G@8"99:&.!0-6&1#E9<2B2,<&"7!;!$.-76%(&(*8B;,G.75'7BAHBCE;GD'1/8,&9"<58.*(+4<8'2C7<.483*7B-&D)2:+>'C;=5E'E53+(:-."B/+'>7)@@)A33*C#2;*<C34@3B(D=(2-=*%04?'0;3/B@4'FE,+39+,(.%BEB
@r2984
AATNGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCAT
+
?&7E"8?4HF&+6D!<A*C,$4%*%%<-=((<<@=(A?$4HE4(@H29C/D6
@r2985
CTGAACCAGACTCTNGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATATGAATATACAAATANTTGGAGCCAACTTGCAGGTGATGATTATCAGCCAGCAGAGAATTNAGGAAAACAGACA
+
E+!0GH3D*=C)=41#2&*%;8/-=C<B!96G4GF)D>B%F0+1"'->=';3A@)@-%:37-1=DB1!?3-$9"5G'8;,1'#.2*(9.9:)9/;92@84%03>)<A0A+>,0!CH-9'#$#8$7!-G$@4.#
@r2986
CAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATNAAAACAGAACTGCTGGAAACGCAGACCGTGG
+
/05A&*C*5*&&6'/@D-(1!D<%A$;=9>/*#7;=)0G9)=E#:/"",7')2,;5-)$63E=!4059$<@>%.E5H3?4*:"3'("G7F1)(.B$5&1)<"7*D>',0>"#)'?442@;"22528#
@r2987
CAGNAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGA
+
@"2'!F(+%A8):&+!;*%:;=%6<!A47"20.$4&<&H$3)5E./>+D/>(9+A(&#</.6
@r2988
GCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGANCGATCCGAATAG
+
0%'$1.?$;<)HE.E>8-?116(!D-B?#B#B@E*$G4F(;():53;+/-E&=+.0>*%3,>7
@r2989
TTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATC
+
)1-2(6,E+=BG#@F:>;;1%4(-'G77<E048@B.6!->!DD442D$-)*EAH=C4:@)$8@4(:FG#"-:B;
@r2990
NCGNCNGCNATTTANNANACNNGNANANANCNAANGNNACNTNGCNNNAGANNATTNNNCTNNGCGCTNNCNAGNTNNNACNCNNTNGAAGNNGTNTNGTNNNTAGAGCNNNTNGGNNNGCATNNNTGGGNCCNNCCNGCNGCNNNNNNNTNNAGN
+
"#####"#$$!$!$"!$"""#""$#$$##!#!#!!!"##$!#!$!!$"$""""$"!!!!##"!$$!#"!"#"$!#!##"##$$"#"!#$$$$$$$$$"$##$#"$$$#$!!"""$"!#!!!$$##"""$$$"!"!!"!#"$"#$!"#$"##!$!!#
@r2991
TTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTG
+
.B143(620#?5)CF-B#C#B/)@-AG)++!!)4";D7<*1!-#(*==DD($8"3&$)#0H-;@-.*4+!&+H?=@E,1;@9-H:%(71BE',*G#5,<.5,%:6D.?!.D+5AE,<,8+/EF:;<-"73'."@=-!4?;-8#+AD="H@$>;.>$,F
@r2992
TTTNCNNAACTNNNTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGNATATATA
+
)&'"!%*#&&"%($%+#(#+$"%&!$'%&')#)(%!)&+!)&'*'($+(%"%("*!&%*"''%%+%&&"'!$#&#$
@r2993
NGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGAT
+
!572016=;A7B,+A$,1,:EFCG25G-;-,A":+9429#3>B=?G:/==2"B5$C?0+*=<@!2H
@r2994
ATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCNGAGGTGGACGATGAAGACCTTCCGCTGGAANGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATNCCAACCTGAAAACGTNCAGCGTGACG
+
C,E982@5$)/C%D"C<'F9;7?GBEG=)&@(>.8>!B?.E8-?1CDG/EE*)%%+)5B1;!'&05;G9F2G1/:$*:/5")"B8HF0<17H=2@G$253>*5?,/%':8G0=#5A;2<$/C4#;FG?%$0>ED0?04;1-&!:F&;"#6)A;$3.@*:B4H1+!??>$7F=0!669/8*-(%$46,2>;G<)89+ED+#+=6*7(#0:<$4",9C",86A'9)/+$;+!141-!26?)>=DC2,2D(
@r2995
GTANTGCTGAAATGTGATTTCTCTTGATTTNANCCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACAT
+
)76296=<G>>5B*09>$B,HD$4@;+!9HF46A>4>HGG!8%B2C8/6+8(2'-:>E;0;*D9+58/475$+:F.;=B08*F
@r2996
AGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATACAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCNTTCAGGGGAGCGGTTTTGAACTNAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAANCTGTACGGTATGGTCACCGGGATGG
+
E-?)C)#D)9H:9;0<<7F%86=&<D2F$G.'>;A=:'>3-5(2.?7.5<D2*7'=)-@.DF8A&'/"2=58?6>>()31#&)A@D,&;(BH'&>7B"A;D?(;0@/*6=;*2'9-6>&,=C'@/G2-)A+E=,H$1#1&!$.-<H11DB7"-"&<@'-.*B62*4-/.11<+6?9F&">//"/)-EE3':6>#%/+HD"&71D9CF;D,/'4&*B((+D/@0<0<'+E?=#;!A!4!448(@4E>685;4D4HAC1"8$H'.'0A"&8!@(C(%"F$,2(H"+#H3:@*'F'2&0&B;<"6&-?B),
@r2997
GTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGA
+
,@'$48#585<DH?C"F$EHB&#2D+?=?(#!(-C5&@34,58>BC?AA2>5'%3/D,0#4,*6;F$3,2&3F,DB%&$90E++C
@r2998
ATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTANGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAG
+
/%+:?<90!&GA@@5>F7!$'((;D0&<30!%$:%,9..2/';=H/5AG:>::+:+8;!C2.;:1,E!(>(<4=-$;C'F(H=?G=(75@DG@1=H%0=)(
@r2999
GATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCCCTTCATCATTTCAAG
+
E=2B6=G2C=,"88E+!A#0,(%-<F*D:50+H(C-(&"A.F;=4<G($:)(!1$98@:"H(<D12.'454/C7&'*&2?BB4:1573;#)15AA$<5(C42*&>$6=H$H<85+#.53>(58%2"A%'F#3F(?*:#.&C)H>:EC6)B$F))
@r3000
GCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAA
+
)/43=("A@H:D$>0,1'?7H0GB:95:A.,8D+!=%$+D;%)B<8
@r3001
TTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAAT
+
*4=0)21;G3">694"&*9*"0"('"">7>:FG3*#1A2F!F$2GE&CH-1HA(59H-$H6(<35:>9AG7
@r3002
GTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAC
+
G6C8A?H='#=A7(+8)7H'F2CF0C9G75:C4!@"("+B41,GG.?4#,90B4"B389."&=:9)#D0"86H50%8?6?!+"4/14C!A0>-"#G%(7-F/#.:
@r3003
NACGACAGCCTGNCTGNCCAGGAGGCACTCGCGACGCTGGCATTTTCCGGTGATGATGAC
+
!!%'&+(&#"*#"()(')()*#$+'"$+!%!*%**"*$#&+'#%%(##%&#+#&(!$!*(
@r3004
TTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTA
+
3=?/@;/'E#&#+$09?H2>(EG(//2%356E,$?&+1@;%6@,=#895(>A@;7?G6/A@DF/!0(F"':
@r3005
NGGCTTCCAGCAACGAGGTCTCTTCCTTCGTTGCAATTTCCAGATCT
+
"22FB5%8(8#'$"B@D!'&68'"$7H)'F+:85>G/+:2!H40+D+
@r3006
TNTNNTAGCNAGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATATTATTCTGGGCGC
+
#$'!&%*'%"($+!&(&#%'$'$#+"!"()%'*(#+"#(#(#)+$'!*$'"&*&$%)""&#))"''"%$#%"%()!"'$#"'!"$!!$"&&%!'%#%*+)*%""!!(!*'**!'#"")+$&!($)$"'!*'&%#!(&*)($$)
@r3007
TACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAA
+
9,?)9&7>2CH%42,+1:#2)0/*;G#*<39"4:167/,C76=F10:,40@&7F>/2GA+2A$+G*&A460/-";($>84C!876(=
@r3008
TGAAGTTTTTCNTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCT
+
%*+%)$$#"("$+'%'**+'')$&$#)#&#'!$'+'+'#+*"(&+"&+#(%$&)
@r3009
AGTGTTAATCTCCTGCATNGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGT
+
9(E@H8+4>%$0#F<F7B!16';.?#*6F6F0F#?8E+!D8%$</)$<?<704!G53,+*(
@r3010
TCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGANTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAA
+
&9H',>/6*;#C,3+>BC:927%<%'@,'&:#5(.>+2+<>6/(:>9/+!-:F4@-2#89:6&($"-%0+<.5C=#<6?#-C-3
@r3011
GTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTNCATCTT
+
3'>C$BEC@3E@/E!),,33>-:;6;A,G,(@2#&<7'*D=<(.2!(<<&7,9?=D/$)B/)+!%5G'!@(@#*5/351@?
@r3012
CCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGG
+
?2%8F/1&>1;9)3)A%).>-,)D*<2G-4=(H585'B6B92026A-(?/B;@<9%9?9-$(1H4B)=
@r3013
NATTATGCGTCCCCAGGTAATGAATAATTGCCTATTTGCCCGTCATACACTTGCTCCTTTCGGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGAT
+
,;!!2B;.*<;0F?C)F;C$$/9:2,A1B6B1AEG4;F<*$>-C5%>F6C8*#'<?%>+5&>*$9GA*E+BD!)B*2F7<";7'."&(G9*B<!B3GBE),CA&F9F?2D('"
@r3014
AAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAAT
+
4-@=AG!.?!D9'#AG"G8@,)'*:3;4#!)5"-!6B3F+;)6&*$(*.H1+*8&'+H/!<0E>9A?122%E%A:=&60
@r3015
ACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACANATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACNAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGTATTTGGT
+
-)"-(#1*&#.HA;=,*'A?+7F#@"G<B',=3).-)@/@329"3%:EC)8>+CDFF%F"GFH'3/:.286:@/2FC?6:63!B,02"#1%A;";"DDH#.D2-.@FG%;B5+56&373#G"!B-G/%EC%B<$('?+G<!;,.E081HD-A;9D9C!6109G'FAA9#*:0HE3B@7='3=G"87)=;@,8%:"5!BA4C+!BG'/9=FE-C%;?32<$G"5-?>,F,*6:;;-%?5"GA.6BGE<H0:<6&B"=DDCHC4B9$7(ACC2&&;:$,'4<*0:
@r3016
NNAGGAGGGCGAATGACCAAGGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAG
+
%&2057?6949=$<&D?0/C,+6#,.:&40C-);F)B&#8*)'(0E00!B-H!@!7=143
@r3017
TGTACCTTTTGCTGGGTCAGGTTGTTCNTTAGGAGGAGTAAAAGGACNAAATGCACTAAACGA
+
@86,C;H56(G;'60/"EH.,'"2&(58(&;&B<'4C8&B9#5?1;B2B2B7.>>/+.-0+@@
@r3018
ACAGTCAGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTANGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTNCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCANCATCCGGTTGNTATCGGTGCTCANGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGNG
+
6'=6!9<#2<C:HA1/<4;-&#+0B,;&B.$C(%"8!H&E8F/A$@=(3F:D=:+A!412,/5.&"B2,:&2521&1&!(4,GA2*(H,/$.*-E7A6*A=&"&77C??/"==&86=98HC.C@!2"6G>EB+?.G%E&!59?B'1("35,6C?F9'=*4A=$":$9#&(F-F#,.,"$&">'A$7-95-,?67'G=9>"<AGA<D5F$2A><D)"F=CEB'+@-)?)BB8F@/A5F(>?!>;:40<(EB%")7F"D75&"-H>(:)-G<4!5"C2%$-++@&"$@$=?8$GEG(3;7-6&)!C<6<?A&;6/&$/%D0=<C%60:0CF>#%-!!:&1*B27:6&C!A:/(.E?337?%B+"!5BE,$.<',8H$)'C)*
@r3019
GANNTACTGCTGGCGTCTTCCACAGTAAACTTCCGGTTGNTGTNTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCNAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATC
+
*%""!('"("++("$+()#""#*!"#&!*+!+%"+!""$)&%&"+"&(*(&&))#%'%+"$*'"('("!$'%)!$%))&%!*$%*#"%*+$(('%&)&+&"$"!+%$(#'%&((#%&)+&$%!'%%"#'&+$')!"+%*&'()&!")*)+$$#(!&*")(+!%$%#%(
@r3020
NACTCAATGTCATTTTCTTCAATGTAAGANGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCNCCTTGTTTTTCTATCGTATTGCCAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGT
+
&(F>:7HC*0F.9;#2A*!:9AD(:+E5)*:.(0C&.A&9<-"5C+C5/$=#E=D7!7,<:)8E.3=+->A39DF;*8AHD&=>,'H;D4&;2'0-'%!/!#:@-+(4G3&-+0-&'0.)D,-C?(@(;2.D7?/&:1$69A<>'1"#6H14FH
@r3021
TTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCA
+
6>1-;*-68;77'G@#-,>(3E65EAH6<'A<#C467@,8+=EFD)5E(>9=
@r3022
ATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTNAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGATGAACTTNCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTTTCCCTTTGACGAATACG
+
CD?)8)FA6;/??8&:,8):<<%:)8)(2E=/'$$:1&0EFF7?.'4!$3@5G*&.>2&/#3%#!D7!..)A@4F,2>3%6<13.5?,$?4,6;FF%&$:&.@AE*.CC00,--$?AA*GEEG<D531B2*):E+AC08)C'D;B,=:6H=D>.&=GG,>G+;+3?!:6:/D:53/F0$5'8%3F0)2#;+.7?5,C6H5B06D$/*
@r3023
TTCATATACCCGGGAGTGATTTCCGTCTTACGGTANTCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTC
+
>#:(9#A0=2D6*'GHC/G><8'=",#):>62;E@$C',%8E&0229.1>997,2G#13.!!CA2&FA35/A.3,D8.,$;',+G"9-/<$3'/%)&9#(6>G+D/%FG0"19=-,3C/8*
@r3024
TGAGCCAACATGGTGAGGATTCTGCTGCTTGATAAATTTTCAGGT
+
&-'$';,,G*B'@GA:<!A*%0$0-G-&(&2,:'%G>B"+84-A&
@r3025
CCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCANAGNCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACAC
+
F&A*=)7+%-4@-*(.D)1$<9/>*2@98A7?-.FD56#F1A/.(+6(&@5E-C:CC@)(.&"B57'+B+A;77>72::*<7+&9F(B:6@G;,((0#*$>04@FEH+A11#<H07+!*47<A(8(55?A)A<&<8/)H:1+$94D#2&.:ADD)'A>F@-:&=;
@r3026
TTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTG
+
C>;EE"5(7=A<5G<G?2=(2&G$&0<;1"B('7=7A8:;4DH=79D'D.4,->F+&?
@r3027
CACGTGAANTTCCAGCACNTGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTC
+
;&6?G%E909-CA@5??G2;$"'*FD441!'7./B)8&F*BC20%E/$*>%3A9-!A4+BA,1!C-28A3:;B4#5".G(%<<
@r3028
GTTAGAGAAGACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATG
+
&"?BG9'H>1B*HA9%0'=*H5C("#$1(5CF)%*62;$3*>)'?5!+E6-2F*+9?.+-B<@52;A1E#44H?=1$6D?)
@r3029
ACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTNCCGGATACAACCGGAA
+
?1<=-1<>H/8C<F8*G9DF7)%,3!(-=A#H;7);65!5G4%%@@D7GH4&E:&5?=B%./C'!F.(D/:*$49!@'0',>1G5G<).@;D'E+$:5-?"9)HB8(!(25G+*>40;"'B#!-
@r3030
GCCGTCAGTCCCGCCTGANTGCNGGAAAGGACCAGCGTTTTGTTGAAAT
+
D'2@<>>.*5.3$CD2$B6CE=G&,D6=@$7"-9<E,@,BC++B?G!B%
@r3031
CCCGTAAAAAAAACCGCACAGGCGGCCTTTAGNGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCNTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGC
+
7%6'*8/G&.!&*?:3-*1.6E!8@FC3>.?3=5B&8*C(=(./&(A'A5=>G$;?0-5-HGD&AH"?)>?.F$"%"2<-:("+0@4&13!9,H;FA86:<C573-/03,-0#!-F8
@r3032
AAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGT
+
2&&('5)4'4%!!8;:("*;F("*+E/%!"*))81?+&+G!'@EF@#:7'F>G<-;/
@r3033
TAACAAAGGAATNGTCATTCCAACCATCTGCTCGTAGGAATGCCTTNTTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCA
+
G&!DHEH2D8&=3"*:%!>B)5E,(?)=+/+:+20>5*!1#3#$55-95$6*@6<@<"E#':,%AA-E$+H#"C/*;>3+<.>
@r3034
GAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGC
+
<<<5*":?7=$F3E3089<)?/1DHG,5">&%1/D7#24.9-(B;@9!9(8G*B6/'.56)F"H;:(=<C673$=H*'<EE/C,81B
@r3035
AGNTATGCGCCGACCANAACACCTTGCNGANCAGCCAAACGTCTNTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATNGGGTACTGTGGGTTTAGTGGTTGTAAAAAC
+
D<+3%A"/5H-3G61.F0/&09,F1#BG.0!1/0*;7",@?*$AGG3A5-)E224C24FD6<F"H8F.%>.->.:(/6G5HA5)8+&)996;G>->!9:)$,A1C;D9?(+A(!+?#67.C&""0G.A0@CC35&%*@G
@r3036
CTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGNG
+
91+B!:1%HCFG43/G*5!.$G"6.#E1)3G0B%$F-!6!$%F2F$=">.##B5D>--=!7F"38+$?C)C
@r3037
CGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTC
+
C?</)</A?9C47:5,HH=0@F:=;:B(64130H=-)?;12G/197>(*>!B5/$95-"<:+.B!+HHC#H*'909)9$>A4.70FG:CH0>*<&./CC'-**8$';>*?C1!C4542G>?+(;E"9AH1D<6H)?":C=B&:585%<H>42D31A<3(F+1#D0@D0#'E:E/8F"C,+(/D0)#)(?
@r3038
CCGAATAAGCCTNAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGA
+
,!=9+7E;(240B(C<,*)A8.+(C@(B".'&<BF,?=AF4H#5-E=8&#D?<.CFE@A5A20DC<$9;D.6G%'"&;?6:4!<"%899=+?@7#+
@r3039
GGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATAAGGTCA
+
"@.,-#"+"9(-(!@8(-E8/BH6.<<#F$%4&4(6@4+-#8:3!5*E!*=!<?"5.EH"7EG%*&(G')7
@r3040
AATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGT
+
!&(@0:4&?A%*8?C)F2&C2;!7@+G8:#=3,8<.$E$,8)*).FGE"83?(C()E+"%,%#CB>BD,
@r3041
CNCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAANTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATANCAAAACCCCGCTCCGGAAAGAA
+
#!.#CA$073%<,-3)";6(9.(>E$#A5:/##".:3A;2(37<>27#79B1/2>16/25"7(@8E%)2D1/<%3>A8=4?:C"?B%?D1-9,G7;$=@+);&1H;,%@!+2?0!4F;?$9*429;;
@r3042
AAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCAC
+
/F<0'9:=+$8?H.'92<(!>#'@C(;C82D4C'*70('!)6+D4:4@>3'(B<A01@42BH+:H@@#1DH?F<7$=;?&,H)/8A(H!;H==B
@r3043
GCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCT
+
-G99$$B<FF$-E*-@2:/#;7G31(;A??G4#)#8A704'A-<A<'%<CEA$-F@98:5&6!>/
@r3044
GGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGA
+
)A7C=-4)$.E;=1#$@%#69+E"A+0"<42C1!%1"76'7G,D6%>FC?
@r3045
CTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTNCTACCAGGGAANAACGGGAAGGAAAGATGAGCACG
+
=6+FG7$"D+(=,ECE4%FA@#02!D*4'+53-;(:,!E$5<'&HH@B?2)D510G+FA?H*B)>A#>-<*'42D*?'=1(2G?
@r3046
ACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAAC
+
-F)#<>DB--0+016G%)2#!"7D>,,E.)3&'20H?B&%8&'40&B&$?-
@r3047
CTATACAGCCAAGCTTGCAGAAACGACTTTNTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTA
+
18>FC37FF<H#90<3*&10E?'8B/'.9:(!,2!-)<*7?H>1"9H25'1,F)7?1DE-/4%(?&4%?<0:+FFH36GGA(&$A"+A5C5H72<*7/H"H$@13;2!;1+0"3//F"#+BB"("'7GA@'4+AH-CE6!/;37!*293$6,,2$:/?.7@F24%3B69'(@&>81!3D:F352"<<)847/<-G0H@89+&DC5
@r3048
NGANCNNGANANTTNNCCGTATGCNTCCCGACCCGGACNATATCGAAGCCTACGCGCTGAACGCCAGCNGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCG
+
"'')#!"$(!$%%)$%!&!*!%#!*+(#")*$)"#$&!)))%$!+!++!**')$#+($*))*"*"&#++#($"+&!!)'#("(!")#")+"(#!*!'"(&)'"%)$!*$'
@r3049
AGTTGATACTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTNACGCCGTATCCGCTCAATATTTTGTTTAAAC
+
752G/?:$6A!G=)<%2=#?-!E-%08G)(@D-,$,F-%E/5<F((*=24+B*:,.$+-.(88#)?A!$"?+!D/
@r3050
CGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACNTTGCATTTAACT
+
(+(#$+()()(&*#&*+(!!!$"%!*)''*+#*"&(*#&+()(#)!!%+!$((
@r3051
ATGCCTGAGCGGTTGTAAGTTCCGCAATNACGTCGGCAACTTTGGCGGCTNCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGNGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCG
+
FF08--G1(!9E/%=E,<.72!;F@DE:"6H&**&;"+FA@00"3$-$D<E@54/@((*("9.H)-3,A"@#B7C(9@'0>3=;-/$G#/2'G)-;B,6)E*%:606@,0:6"55=E>4->H&%="'.36#*F66!=)@D5G.'CG#+G%=9AHC$%-'H),G=&55C:0(A!#A.#,8>'E'D8C?F>%,)(+;('0("-5B5$/G'219'3$0&0=#*?/D#+AD,@)98B
@r3052
AACCANGTNTGTTACTGCTACAGGGACCCAAGGACGGGTA
+
&*&#(!)!)$+)*)*")**%)"%!)&"$)"!"(#&$!+""
@r3053
CGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGG
+
+143*)'<-@<1=D&7,3G#2E+:F#@4F#;%??D?5*0A,"4?A/#,3HE5/%B<+4D9#21B"E.+C4-B'<D$&!)/'A&5=;0!0D2#C9(&.-FAE+F2-@04BC#5,?D>.15!=A2-@=%5%>:G02D.G/G9>9A:E>3-9+/!1GB.4%H4%>/C3;%(&&$/+!
@r3054
AATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTANATTGTTGTTCTTTCTGCAATAAAGTGGGGAAGTGAG
+
A+-%0D98CAB+8D'D4G15:F:6H?0#))50?B&F$=';1(8</*@9(<):0BE=%<8*9*.B%"6/A;=/,-%):A+EG'9;+?4B6;)DCGH0.*'#H.E8>34HE/C;:(0F74>;C8#4>9%0"/EG0,=!
@r3055
GAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCNAACAGGACGATATTGTAAATTCACTTAATTACGAGG
+
/4"$5B/'FA&-C$C4(G!*#!0&%3(5#>'#/,A*HAG(2;C8(#5$3,05@3E#5.@+C6@3F/(C;"9:".4G7=?/DE**6;*9:%=@4EG
@r3056
TTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTG
+
+(#!+%$*(*#**%*)')#'#((*'!%%!(!+""*$#$$''$%"%(#+))*#+$)+)&$+*+*)*#!"$$()$*+*!$%%&
@r3057
CGAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCANTGGCTCAGGTTGNCA
+
%!,#?(/D6<"$+=&<G,<,C->5B6/1>&C5.*378#>9FB;&>&6,*A*8!C"&>1+'!B%F,!'(FF%D8>A"A,;8G:1>(8>F#,@2,=
@r3058
TTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATNTGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGCGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAG
+
6@5H(GC:29@?1-7"*%G6=!$"6-5!+<4E%.0947%.:9'%0,44?5:+.A=85B**?#9F@*?C,=/(!,,72DC,(;!.'EC$G&:6B=:-7*,<&-.%=81&*,:"HA"%<&'&4.%**>>C2H/0-FCBGB?*4"*,;<$-A/"(9%!09#,,#$7*CE-"8A).1<''-H''0E4?)"4/6)'0+;<@:0+/A!3@+
@r3059
NTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTNACGCCGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTG
+
$@,/(6--E,&*6F';F5;F5'=%A<#>*'18B+G(+/$&7D?B(28%"HHGC70712)5),!GA!:5E;6$@3&@3'1.9;*B8HEE008:$.7!:!7E0AHD./A48@1<+=,+E"8B:HB:).'>?(&2:8-+!C/C$8>+3F(1B%:
@r3060
TTATCACCNCCAGAGGTANAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGAT
+
<AD"*/B/*,;5:E<E4%*0DG@>@8,CA,&F$HC@D'52/87$2??G%#1;,>GA@>B$">:#;F0H
@r3061
CAACGGGAAAGAAGCTGNTAGCGNCCGGCGCCTGTTGATTTGAGTTTTGTGTTTAGCGTGACAA
+
/-"@-*B3'01AE%643E*G#879D7<A#.+<'"(!21H9E$;C*%%6+4)H6D/=B?C,0,"0
@r3062
GAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTNAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGC
+
G)A-'2,C>:'C,65&#H1<4:D#+9%&15G>:;#6C>D;&?3EC@&?6/5;2#;3))F45,/00%:#G;E2EA*"#-B?+9<#5"A:G"%%*&7H;7"14,%&6;FE@D4*&F%@+?<=7BEC-%6>(8$DA61C9>975';5:=B*&,;8BD0:)$B/+3"+;*47@"3'&#E!-
@r3063
CTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCT
+
C+90%,/,%3!5)"H5>/&<3+!8@E8+6,3,<03H=''(;
@r3064
CNCNCGGNNCTNCNNGNCNTNNCNGNTNACNGAGANGNTNGNNNTGAGCNANNNTNACNATNNCNCNGGTAGNNNNNNNGCGNGGN
+
!"$$###!"!"$"$$"#$"#""#!$"""$$"#"$#"#"$##!!!"$##$!"#"!""#$!##!"$!$#!"$"!""#""!$#$$$!#!
@r3065
CAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTNCGGGCCGTGNTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTNATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGG
+
?:D=<F25!H&2>=!&F""G!.=B6,@B=*")H#.((<5(C6ED"870E:@E,(-!<B?=:4$2,-C6FG)@'4?4/H@.H9F5-;*4'*('-FC5=@A;"@"5BA"1/<>9,C;@@G#7=C*;7EGC5?!4H2)?#A,-*@B!0!,1*#4D0=%C,6*)=%;+AG9"4D(*#:B%36!G0*7>/=G&6>G+
@r3066
GTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTNACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGAC
+
'7G4$%941%'*$+;==+@>%&&0:%':7$;8%+'>?,1!1B9E?))D9&&C)72-3:89.:%=H?91+-2%=:);';.=*&/5/+8!@61859$&?8"*H(,G5B=/%&*@?&<:$)"+981=+.)"1A1)A0C
@r3067
NGCAGAAGNCCTGACCGNCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCTGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACNGACGTAACNACCGCGACATGTGTGCGCTGTTCCGCTGGGCATGCCAGGACAACTTCNGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGC
+
)C.1#291AE19=(6','EG6C&5B>D)3;(%8'5/."96B!FB527$+-2$?:<%F7..DF9C%-4C14?7./+*);A../-<$0&#@B)*!A7H$!3@+2A1GH9>*21-!78<B/!#(#C+&G.,$60H-383/$/E(48EC-166A+@06$$"**8)>HC8*2.G(6&7%=00$<-9"6$D6(@3"*@,(H"51=F)=G3F=55$H.FF-%;;2FD3H!('*=*@B:C:8;.=<4.D*%$87<2C>C<+&>=#)E4B9
@r3068
AACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGGACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGATATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACC
+
/E((%?+=FD%#AH*1-0$(C<>3FC16G4(F.!%A6<&C9;H!A8-&80<D27BE0"1:*'1<:)'8$H!<:+1=!F)$#)+&!DBC>8/:?=3$78E-%&37@2B$-6=:,$F6&')6.94#3#$?F?.>,)8#1'310G!""5/-(E9*&+*@26,!6058:-5;$+9/=,G":7%!@C57<H'/67116<%;?>66#@,D#3)A(1-A
@r3069
TCNGCTANAAAGCNNTNCNTNCATCACTGAATCCGGGAGCACTTTTTGTATTAAATGAAAAGTGGAAATTTGACAATTCNGGCAAACCATTTAACACACG
+
#&(!')"$)*)*#"#%$$()!'++!)()"!&)+$#"$"($+%(*))#)()(&%!"")*')"!++$#"'(*'*+*+$*''("%%"&!%#')#*#&%*&%''
@r3070
NGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTCAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTANCTTCATATTTAACTG
+
!41!':(>$#"44G27-91AE4"0)>DF+'FB,'>9,A1)CE?,>-,<=$/9:8//-H069'9!FH"6F,%4H=*,1$+7%,.)2)"()GC<4#@$>=9$68C6*C:6"B!77):H'C<7)1B,GB$!%6(GF-E,)&7@+*8H?'DE!9-'8$@
@r3071
TGTGNNNNGGGGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACNAGACACCCAGCCCGGCTGCGNTNTACCGCANCAGTGACTGCTCAAACACGGAGTAGCCGTTANCCGTATCCTGAGCCGTCTGCAGGTTCAGTGA
+
""&'""$(%)"+%*#%!%*!"""""'#$*(##)+)*&)+&$(*#"++)%"%%'%"'*&%(#&%%")!'$$*!"**'&%!(%!"+!)('"&%"'#$%')'&*'(")'*")!*)#&&%*()))!'#%##'(*'"*%&##**&##!'(%
@r3072
AAACAATATAGTAAATTAGTTACACAGGAAATTTTTAANATTATTATTTTCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGNCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGC
+
;FA0@GA3%C?,5H?@><33-'2H=A;%G31;A'(@AC3?DD;?5#".&6+?9.HB;49F"):6!F"40'"4C=05!40@>;00HA)(5(*';!G4=0/$<B)!-&'@-(7$5*/5668*4%2?B#BB)+F$9D.,A=":-7!7%?,85G3*?(*
@r3073
CGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGT
+
F:C)*4:<=D",*"*#/4E293'.F;G%;>&59':"!B/E'3%?7*9&9&9;#+=/?@CEGE4,(';EH4;1,2G3')3%"H9C9*/<6.394/HA
@r3074
GTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGAAATTTTTAATAT
+
C/'-7!:)..-+DG/,%@2;0/7;9021*(78-'.H$!F7-1A=+0;F==83/0(=@&F)2/F!)+,49
@r3075
CCNNCGGTATCGACTCCCAGCTGCACCGCTANGAAATGCGCGTATGGGGATGGGGGCCGCGTGAGGAAAGCTGGCTGATTGACCNGCAGATTATTATGGACCNCCACGACGAT
+
$*%)%&+$$(*"%"*+%&(#+"*$)%()$!"((%(+*)&+%#!"#+'*%&#%*#&'*(&#*#$%"*')(%#(#%)$*!#)+"#)"*"!()!'$%'&$!$&&)%&*$)#**$*%
@r3076
CCGTCACGTCCACGCATCAGGCGGATATCGTTAGCCCACCCGGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTT
+
'A#+"?C/B4&0#--9-:::4F*CC.-=.A-+$@!&=$D%55#.?8"C%7@7FC)9=,!)=@D*6;/#'9:'5;(2F?BD?;&43.8%,9C&)1"6@>@/6=)$E)9FF('/A/!!??
@r3077
TCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAGTCCGATAGACCTT
+
9F);/4C)4-6;HG7A9;<?'@0*;/9'&+0/&,G34>*B*8%7-&6E;#:<?2+.635#*
@r3078
TTGATCGCGCTTTGATATATGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAACCGCATTGCATAATCTTTCAGGGTTATGNGTTGTTCCATACAACCTC
+
9H<D%.>C88#00:G;:H#0-);<D6-)(/4)($=1@->H5)?H+"'?#/F.H269=:&(6-E';!.D="EH328H/:>/@-'@11@20D/7&,@>@$2H
@r3079
NACCCATCGGAAAACTCCTGCTTTAGCAAGATTNTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATG
+
'F+192*G<<%)#<$=!68<>'E0A@5D2<3@#9;>?+DH&@G4:-5*)F=@&4+=E5)@:.8,"5+"0!GBD)#D*&44!D;A99>46)#&072=#'?
@r3080
ACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGC
+
AA5GGH?%8#D"/%?3EC,&B0#=,:?D$'4?"-D8,E?:12"G@9-#*B
@r3081
TCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGAC
+
4*806?*4B:C8=&'(%13#G>00A<<5@)+.).<=0;<7C0#7.D/5H-@
@r3082
GACAGAGGCAGGGTGTGGGACAAAACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAG
+
&1"G(D1:8$/"7=+9(C5?*$!>6F5<1)2(.:&B?C@904=(E00A?<D80:>HC61=!-B)!:F=*%5BE-%78)A%+1B/4")2#@6C/-?1A+F'"7D(")H12!80<A*3/651"C(C95
@r3083
GCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAACAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAA
+
<0(C-*.6!855:&@D,D$%%"D=360//@;E8/B@-570!6F2C4B@*>E-&55E9<77)A$)2=D)$H4G&#98(C:)32:H;@,?(9
@r3084
TGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTG
+
>&$=C6:D2-E+(%'/)(&$0CE6!0H#"(D00H+$5E0.$8@))&'D#:G*(!E2#,'C#3D@@+,H$+7FA?H:0+D--C'295B&@9)&B)#8"/8-B2:C-6@;4@?@G,':7@*B645BGC-<9!13$4"AG0,5B7&04</BF(>92%
@r3085
TGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTT
+
B?7B:*/=.<24A7;6*!$'!CC%%,+G4,--(!%?B=00!24&@A2%!&;$:9,-AC6A2$2A.219<<B-=BF1%&G0/-&)1>"A$5!G&*2>0BF#,>6>B<1+764#&?!3$)A:0&5<?B;9:)
@r3086
AAANNNNATNNATNNANNNGGTNACTANTNATNANNCNTGGGNNANNANNCCCAAAGAGTNNGNN
+
#$#"!$!$#$#"$"!#"!!##$!"#"#!"!"!$"#!"$$$$"$!!"!#!!#!"#$###!$""#!"
@r3087
AGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGG
+
%=%*3A01)*9'&?'+5?A!-*:%F%G<=)<&+H74?G!$3*F*!.#
@r3088
GAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGNGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGT
+
%A,G7GC$:B&F1H%7/;43D736@$.!5!<"/<E;"/*1B7@%9?@0!;6+<%!196%6,(8!<;?7FAA.8?8$(E3(=74)&7+H:<3&&B(&$A'/.&?2BF8.73!G-DABCA'>>&0.(3/1A%A%6B*'A,6H;&H;
@r3089
GTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTT
+
AA9G+9'$35"F.$CE"6017H>13#@:>:9)9&"53,A/$9?2&,#<
@r3090
TCTTTTACAANACCGATCTCACTCTCCTTTGATGCGAATGNCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCG
+
@,::0+)G7%(>"&)6(G)B*DC(!+34,&GE=F"@ECE0)C1%817@(@;=-2%)13!>47C<:B1"%A'99>4+9E=7*#&?(H1@-=-25-"21..<)0':A!37F>*,&:&9A%8G'(GA14?
@r3091
ATNTGNTTNGTGTCNNCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATG
+
$&!##!()$$($$)"!#&+'$)"+$#('++("%)$)$+%+$+"#')%+%$*)+
@r3092
GTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCAT
+
B6&A.32((,"A="4'E"&.'C394)'HFC1'14!>:&053E-(08*333>0*,)?H.E%!6@+00B>*)3;&>"5+*()))>"@71D3(.(9:,A+@+GAD
@r3093
TCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACATCGTGAT
+
:HH@<54$@#>G=D!>E+?#DB&B02@@(%A2DBCF1263%;(+8C0(<""."!03D*2&73=!'6.
@r3094
CGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCNGCTTGGGATCAGCAGCCTGACGGNTGCGGTGTCCGGCGACA
+
1E:+<582''-10;5)>A>,27D9;(D;8+=5EG'<H/66BBC2;<=""C/37+FH/8#62F(;3'FGF>6);>H%+656=0-:@DF4-3:,G3>C
@r3095
GCNNNATGTNTTNNNTTATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTNTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTTAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTGAAGCTATTCAGGATTTAGTAGTATNGCCAAATCGATTAGCCGACATTGAA
+
&!)')*!!#"(%"$!("+$("$'*%*"*")!&%*#$$%*)"($*&$)#$)!$+#"()!'%#$%'#"(!&(%+$!%#!%!*&)##)('##'*%(&&!#$%%%#)+$%$#'+%''*$*'$!**$+!"*+"#*'$!!"(!($'+"""*('*!!(*$!$("&'&)%'!*!$+&%&*(*%)#$%
@r3096
NTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTNAGGTATGCACCGGT
+
!*@@1C*4?>%+7"?"?)5F>B*<G)/DAC&A<#2@-H>6A157$":#,)-,G7H8EE-'!H$/$9-$:!#10'()E&*-HFG-3G3H0!#2*-6C
@r3097
CACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGANCATATTACGATGACATGCTTTTCATCA
+
>#.'G*5G95?-##-)5?3:?67+?D!0#+A*H)@?=!?H62;+6?(A/25GH'$&B:9!:9F-A;>/*>(D03!-D)5/56<@F.-1<?F,'@G988,'1H+/HC;,3'1'$,G!B-/:A;,7'#0%-/A/
@r3098
TGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACAT
+
G;7;=6@*D0>-#%?EF38H/E)#>C!;%1-,H:$*#=F@AC,31,#-'&
@r3099
CAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCT
+
#<;0$$H8'B<C"GH+C09:B"B9@45(+B+7.G@8>061A:"DG-0#C+
@r3100
CCCCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGNNGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGNGGGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTGTC
+
)*!+!*)($("$!(&(+%'(%))'$+')&("%!%"!+%&#'"#%&&''&!&*!(%)'+"#%'#'+*&))((*#!+"$))$&))$+$#**%+%*)&!)+&$"&&'*+$#**+'($$#(*"('*+')("$)%+)"!'''"+(!!&+!''+'$)+(")&'!$%"$%$&!(+&%$$!$+%*$&(%)(+$&!(*()$('$)("%&"%'##"*&&'%'"!+!++!
@r3101
GATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTNATATGAACAAGCTCATCTGCGGCCTTACGGCGTAATNCCGCATCAGTAANCGCAT
+
)1:8F>"E2@BD(2@C9@.C1/-%2-8!56.3'4BF##1D.8<)&?:'GC>)57?"=,8B6B<4:+&41F&G%H8?%CH(+>4E#G?6E<+9/,78-@EC!>+&$)A)0'%F&D$H&,=57/'*+?(4<H-,5='@%"-=+$F96(28A,#B/-B9EH-=9)?,0?"
@r3102
TTTTCTGACGTCCGTTATCTGTTCCCTCCGACCACGCCAG
+
.6)<H/;7H''D.$G!*H.F'E>&-*'."<;32%>*3+&G
@r3103
GATNAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTT
+
(,39;3GF2!8/C0..9G19H&4'<=B1./!("AB".E=?@'.,7H3061G,-2&3557?H9F!2A2F,$H<2:2#C1%&4;E'=*H:@2257>351D188@FBE+!C++#F*81"8*HH*-
@r3104
AAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCAAGGAATGCATTTTTCTGGCAGCNGGCTTCATATTCTGTGTGCTTAT
+
5EF!7>(#D1!()<0;>9>%D(=D75%*D"B=943%#,7=@<>09)G2"(>**#F#60;D,;=>F7(+#.,B68@D0("HBE*)
@r3105
NATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCACGAGTAATTATGCGGAACAGAATCATGCCTGGTGT
+
#%%+)()"%*)&*$**'()$&%%+)%&*+!$'!+(")&)%$$""("%(%$#($)')+)*!!*("$!""!%)$)&+&&*"'&'#'%"#)*"++"*'$#%&+&#'*)")!#*%('
@r3106
TTGCCNGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCNATATCTAAGTAACTAGATAAGAGGAATCGATNTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCA
+
9(9H/)%$EH&E-+?8-1('D"1F+$#0"A5.:@8)F3+!?%!29/B4G%7>CC)$->.:86;')*H27$(='8&4EE>D*99C4,0EC#8#764":1F9A1D$%42<//,$6@#BF6(!$/<70<*0*@F@'E>=389$G;E.!0E84/!?$+$=!;09.
@r3107
GGTCACCAANGCTGAGATAGCTGAAGAGATGNCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGAAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGNAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTC
+
2$5;$/$1)?*?,!2)%26F'7,C)6FG3-8227,8D0>'.9-(!28B@*6/:&=)@1F>9A+H$$@A526.D?6.8!,+7*$*>:829?7>935@C..?@!D*8<6&A!FF#%;3F(2F<(@C$D*;G)>')6=)3?5'B9A?++8$B:=H>1B:*9*+D,A:E=&E<C+1#G8A;@2ADH*7AB(A1@:&2
@r3108
NCTCNAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGGATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCC
+
!)+@4"850/85*+=7!GF,<&"@(>CCH3#A"#$7"(81;01?8"2E5,!G;:,6>4!)8.BF=6H*5;:D&33*1?4>?<';F,-.5'@?+6'C/:4=*.7D;,4+07C=,>00)&F>D3>!H;6('/@7$H3*B$&DE0:-%83$176!4A7F%9"A93%//)0CBH#1:H)63:95+G4>+#D?.)5(8$%C<!0
@r3109
CTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGC
+
C(=#)(C52(&$"))F?3!A3625(#"8&($=3/!$)!6?()-;7:5"<=%$9F:",E3>H#)?>3-9@6'#=(H!+CH;>60=))D6"'<!F!F)'395$+#:$%$%D4-H);#E2%F-HD)%A%)>,A0!'7C4B-B9)0*@1B9A(,
@r3110
NCCATATTGCAGTCGCGGCACGATGGAACNAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTT
+
"$+#($'"+#!+)$)&(!*('$#'#*%&*&'!$)#"+%()'"+(%'#)*$()))%"+("')"&!!*!#'%*!")+!+###*))(''#$&$(%*
@r3111
GCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTNCGATTCAGCGAGAGAAT
+
3>2HB%';6344$?)90.$*6@=!<:4(F<9#$E!+:=BD>@/E!@C9'7301H-H))&AA#A:#0%H9>@,:0H./9BDB6@E5H&A"""/50->8#(&38?H/,;H='"=2$B-?'2.7;8=<D9'03*3-E((('7$#<"#*437
@r3112
TTTGGTTGCCGACGGATGATGATGCCGAGNACTTTATGAAAACCCNCNTTGAGCCGACTA
+
5.!#G:A'+<;,)0&$2)'%D3)?!'<D1C;+-;"D8;.=B=H;*(74H255,*!8;<&9
@r3113
GGGAAACTGCGTGTTGAGCTTGAAACNGCAAAATCAAAACTCAACGAGCAGCCTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTGATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGNTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGTGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAANCGACATACATTGCAAGGA
+
"+!"')!%*'$&%!#!!"$+')('&%#&"*+')*'!#!(+'+!!($*)$!+*!"&!'&(&%$$+("#"*&)+##&*"')"(+$($'*&()!'#%!'!$'$+*'&&!('&+*&*+$)$&+#'$%'&"$)*$("$')+*)%%%)"%&"%(%"*!&")$!""#&'*'"%''#)$'$&"$*&"$"!**&(+$(!+)#$!"%*!""&)%(*$#(($%)%")&"#&*!&)($!+$)+%"*&$(&(!$%%+++"&+"%)"*#)+*'#$)!'%'#((%'$(!!!("#!!#%$)%'(%$#)$*"('!$$"(*%&#&)+$)"#'"&)&$#!(*&'*$!%(+%*!"*+")+!$'"&!$((+*%+)+""!%&+&)$#&%&&*&*")(%&&##&"&*!++$*&!++%&(*$%()!#)##!%')(+%$"*(((&++*$+$)!!%$!%*(%+&)%$#!&%%$%(+'$'!+)'($*$!(+&+&*!!&"#+*'&#$#(*$)+"!"*)$"'"#*$&)($')*(&%)'&**&')*'+"*#+!)*(($)'$#&#$$#
@r3114
TGCNGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCGTAACTG
+
.-'4H9.21-%C'#G!1D?3>:8>$F758&C#!82?'4?"?'29G5:;A;B>.'=!"A+D!-(#A?.6EG.4235>A?"(>3FHG.A3EF3$7+%@*#'>*!>HGA;0>"4<.&E2&<%?5!>1HG6FE.52*1/3
@r3115
GATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCNGAAGTTGTCCTGGCATGCCCAGTNGAACAGCACACACATGTCGCGGTGGTTANGTC
+
63F%33#!G<8#5(@C;4C7DG8($"2*+$,F;6:E9)B/++0>H))1/='+2589B@--;C$.C$(@C,).E7AE@)A%C!A1B-E>&-7(DF/D.*:B+.6/&6E57#$"+@$!
@r3116
AGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGANTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGACGCAGAAGCGGCATCAGCAAAGGCCACT
+
?FF>6=/-0E6<34)C*/%HH+=3;H8C-'&?E=@3;/>%1?07:0%(*$"=1*.=7/(?(,;A90#4C22)5@-:&C,2G"5'!*/BE='C:';'0D/E+4FH#.G,-.%.7?1-;H!'A-8*EE1CB8%6@:@.(%)A)-'B>=#5(&9/#C
@r3117
TCGCGGNGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGT
+
'+%#)#$+&!#+')+)*('%'"*!$'!&%*(*(%%((&)'*!'
@r3118
CGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATAGTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATC
+
1!#F$H'5!)=#5F*,3DFD*1744FG%$7<&6#64"90:G#9.:>+1HC4:!B$29H27<G;BHFB+/*$'9%;)'@'B2F)!9&G;,3>+.;!?>#9?DF6EA"A-B/1<96-.F6!<'5C4.("4-:F1!H-<46#8
@r3119
CTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTC
+
56/,=#01.?:#B;>H8D(57/4+'!"+-D!+D5.3?'8:-C
@r3120
TNGGTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCANTACCCGTTTCATCGCGGCACTCTGGCGAC
+
$)%&#'+%(*$$'&+*!'+#!*#("")&&!++'"&#$'#%%&&*++*!)(!$($+&&*"!&"("%%))++#+)&'!!(!+
@r3121
GACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCT
+
'=>BB+%>@#$?F#>6=6BC;$H$B!G-,HHB54:<<B:.<D93+6;G7@8F=>BD5@.E95?
@r3122
GCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACG
+
9D.;*%"-C9F#&@D@A6/D@F@10(+#("'-"?3/75?@?F!64
@r3123
TGGTTCTCGGAANAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTNATCTTGGTACGGCGCTG
+
0,C$&9#2<<$(<6$1<:,"<><4:G5'5HF0*(G23=3>A>?4)#3>F%"3:@*?H8,?1HA/'$0BA0(>
@r3124
TTTCCTAACCTTGCCGGCAATGGCTTTGTNGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTGTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTNAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCNGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATA
+
(FFGADBH,3%'@&D++?8'9F:C2E1@?)CH'&38G?B7(*0-G*;F41A";4G>1$+@=E><&G!(;B'=&"6=&6.)1@#4?*H"$1B)9E689=!/3,>!B%7(+>(2'/E)(*,/9$2&83,AA#6)76':61(.7:2H6!!4%D('=?:7%2D'EB*$<!A4D!#>>58&+;.8=(C=H!>$.<<9%FC)=3E/&H9;HD*8&<=7=A3/C&H1,;)C(*)%E;F,9%6#@BEAE+8A->@-B5?3(+6AB56G#-=&("H->A)),0-B36&D1,5.DH#+06D;F2%%260&DD(F:>*'G$@B13E=+'E-4&.@C'1<:DF#'5B<7/<(3)22C77,D;3&%*208>!2.0@21E"D4":)/9.>25H<19A4/(:8)H&'E.?C.74'!<(9C=:-&)$'06*2CC:H6'<'9<FC-?E#
@r3125
GCACGCCGACCAGTGCCGTGTTCGGGTAGCACNGTTTCACATCGATNATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGG
+
E?!)!-GH::#/@*!4=@='D23A>.*7@.*E/8BF-)5GD-F1+$0;41)#*(+$7271+*0&+2-".19G!3/=,2?1"G/*5/-7>5)4,#H2
@r3126
TTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATT
+
'$'>5=41G'B5D>A&@2"3#7+.6H25.04!%,3G9:19F@,*2'(:/7$#!>2G5$#@'
@r3127
GNTTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCANGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACANATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGNGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTANCACCGTGCGTGTTGACTATTTTACCTCTGGCNGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAACGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTANAGATCTCGGCGTATATCAA
+
($"&#,/*@!7(F<2$))$,?(-5A;-9($02?@&G*3$H!H0>$@?;!F3&C,#+:#E00H=,'#=&7-78(=/'3(:D>F=,D81DE"F"1'>0#3E&;'=.48*?F->*6=79E,BD"*DC,%E+6/H?0/-=D:>$BC%.'E@1%H%<C)A2*1@9"0+=9D8#'""'9?5-D"/(:4=!!>C+,,(*=5A"C1C>9728<G=.>=/71.E5B*A,"44.-C-->8>4-"G6"/8A>95!EC#*05487<";/7?0HB+D!644>75;:"5<E$E-F9D(5:G+!.0&/1C73B0G.B'26=&'8D%1?B/H$HCB$<)72%"'62DD.E=2H7'&%)3:*#37=)!AD-GEFDBE;G$&)G75#B:'=:2H+&E5'B-$(E=1H.)2+H03;//"D@5*68B+$4#/2=E/D)9B$)(@
@r3128
ATAANTCGTAATNTTTNANCGTATAAGCNACNCGNCGTNTNTCTGATTTAA
+
**#)!*(())%"!'*%"%%%&($)*'&'(%)(#""$$&!(!)(++&)'(('
@r3129
GCGAAAAGCNAGNACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGNTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGT
+
'/1G3,GC/EDF%H<0:,2"%??'*:);"@D;4F3G6%7#$@!F$H;G,3/!27-7C<@!5&D@%"77C7<C#,3E,(;6&DDE8&?)D3-(,);#;2<D$)0A
@r3130
GCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCANTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCC
+
4<&.2$$86.C/="A6/%?1B/H@,6??-4/C?4"((+907!#24)@,#*"+2B1+!026(!6-)71F'ED<:E6$6*5.19(#:"<#=:*H;89?",?
@r3131
AACGCAAAAAATCNGACTTGCCTGCAAAGATGAGGAGGGATTG
+
6C4",'2"&HD,:EB3&+>1)C<("//=2*<7+</(D>E$1B=
@r3132
NNTCNNAACCTTACAGAAGAGCAATCTATGNTTTTGTGCGCAGCCCATAATGAAGGCAGG
+
$"##"$(!%*&+%&!!%#"')()#"((++"*'&+&%''*("!($)+**")$*$'&#!%++
@r3133
NATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATNTGACGTGGTTTGNTGGCCTCC
+
!&.0&!%=-<G+6%G-F2%AG/CH84A*><=0++GD4@4F<6@8*>8%+&0A+DE$*-3!AG1!+'89H/36F<7?A8?-C%G@;<5>(,DE-#''>/.
@r3134
TTTTTCAGCGATCCGGATATGCATCCGGTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATG
+
-6F&+2579=.F7/-+1&7:8.032:9-*E@@DD:1D6-,2/&%13&9E>177B"+6B5*77,<-@/-22:1'%%0(A4C67
@r3135
GGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGC
+
)+F>@+,%4-@3!C.#!///+;-B.<.-5):>F6!9?F*#/+<%@+=*((#50.@(?!7+<@,<,DB>=6C1@$1830%H
@r3136
NGGNGNCNGAGGNCCGTTATCAGTTACATCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTA
+
#**'$&#&)*#+"'$++$!#+'#!%&'#&'#()+#%+$'""(+$&+%*+!%*"#"&#'!#(%&*$*)'%&(*$'#"'!)!
@r3137
CTCTTCGGTATATTTCAGCCGTGNCGCTTCGGTATCGCTCTGCTGCTGCGNATTTTTGTCCTGTTGAG
+
+'"$$!+!)')#(+#&')$!$)%!*$!(+"!!+($!''"#'##(%$%$(&+"&#(+(#&')($((&$(
@r3138
AAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACNCGGTG
+
EG%2-&$!G7+'":??C9<$(2?.2GE49):F$'9?.H)'22")F58:&)C"4A$"0>
@r3139
GGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGT
+
3&D3$9D<!?.>A1:1+=C?=")6F91-)+'+'7%G)C&,5+=;H,)CC99,/6H0-.0')B;")@9!4-9'H1)D0>@H76-1-1C@0/.;B,67?$1"/C@2D+/E=3B+6"F4!@'@*E@#61'%!2D,6@7H,B3:2<-%32-)C/%
@r3140
AACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATC
+
9*!E*C<2$7C0)G"!)FC"-D1.<2-16*,1?,8H+7"5>48-AB
@r3141
CTGACGCTTCAGGCAGAACTCCGGACGCAGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTG
+
DH)0/*HC:1B7D8'5#==4+EFA3(CH/$83/9:;)1369,$!9@C3+H?0$9+&A53)40?#55(#?#/?*#*D?5("@-!
@r3142
CGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGAC
+
8&?!E8>**DF+2%C?+;.G18#*;(+C4<"?>#@003B/F.5$DC66#692*"@)).0%%3(,*05$+'-)<!D639!H5!%@=;@@&2B4CA
@r3143
NAGGCTNAGCAGCAGACTCAACAGGACAAAAATGCGCAGC
+
!/<&5C/HC8@*8"7;)8&@9/0")?(',CC6,"!1G-DA
@r3144
CGCCCACCGAGATCAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGT
+
9E#,"#4*")8<@.E@&(.:)AF#'65F(?+,6=,47D:GF9@(4>&A-,.92BF6!9E22GC>@="A$5BD
@r3145
NATNTTTACTACCGNAATCCACAATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGANGTGATGGAACAATACCAGGACTATCC
+
%##"*+%(%%+!%)(+%!')!!%('(#$$'%!)!%!"#$&(%++$)+%($!+&(#"))''%)$#()+%"!%"%*("!'('!'*!"%#&))&#$+++%(&*)
@r3146
TTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACAAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCA
+
H=H4/.A9)@BCF=;5BG6'E2.)#BG+BF1A0()*:AG"9;@3/CF&%!%7#DE:(%FC*$?HC3<:*75:"E6'4?)3*E188%1%F7=@F*6"$%$+C=">?-
@r3147
TAAGGANGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAAT
+
%>.(8'E6C1</81.?4%".C@6F6-1<-,!/*!D774F<0'3*/9)0#$&0D?*/25-#-
@r3148
ACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTNTCACTGTCAGGAAAGTGGTA
+
G!>,69%E#,)5G322';A@)0E.<HH?62*0(0/2C0@3*B15H4G85%*"5>46)(!/?.GE24#FA0;-G.2'C>D/9*",-/645@9'!/-;""4G?.%"A6!5>,&D3='''(3;(?>><,,<B*3),HH=.&D!-0CE?'E(,+E>=<(>0*F#3A(+2F')/A+&D;9+9CG+!8<!EG>2B)#8$+,,AA6G:E*>827>)B#F2A31#C@F:7;D6!!#-4!2H@+5)/2:AE)*?A?5&7"0)<F?D=!9A)"9!@=7$$5G<1C+?D7C.B?5=$A!.(3F(E$4.A2F4+)#0?1*'!)5AE';(&.34E>
@r3149
AGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGNTGTATGGAACAACGC
+
H!#E6H'A0/!E'>.B>-EC3@)6&"+)'!C405B/:4"4)2(68>.8"9;8/D,FA+0(=,;46=7:+/="'(=-6+8F3(;4*-0"$/34%??)<&"=)3*).%24'2==(98H77%('>H+1G//3,&-@$<D>6>'B;HD*36,@CC%,;*"8;#9>1#>>$6B
@r3150
GGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGC
+
-GC()GC2!(4"34"#3B8..E.482!+0*?1E(*H/)F4()6@4*>1&H70'<'7&!G(2)H+.6?#15G.5!GA?4@+1B.$?#9;,D
@r3151
TATNTGNACTCGCTACGGCGGGTTTTGTTTTATGGAGNTGATAAATGNACTTCCGAGTCACAGGGGAATGGAATG
+
%*'$%(%#**+$"%'*&&%&"$%%#+(()((+!+%&)#'"$($)($&'*&"&!++("()'&%')$%!)*"%&*))
@r3152
TTTTCCGTTAATTTTCTGGCNTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCGGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGT
+
1?9.H$9&*%H!,D"1C;H,2!D15;5F&;$(',"9?29"+&"-.7"1:0>ED%DG#9"</'1(?F;F*4$7@$5;.)0,6HH1:(%A'F>6E<")--$#!1D/@&E8G#+3G1C=%6>>4,D*A=5((.4),84BF3A80D2'&&F+&$;A!9B+E3=+;;8@CE$&#0F)&%"/F272;?(D&.H.;*,1,;BC@5<(+4<D4,.580*/)8'!57/F4/%=!=;"1%AA*G.5878H810%#4F=,<0D8'("F+.0,;&)#GC
@r3153
TGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTA
+
@-+-$>9C13D,!#5.,%DHE7$1.;G%&388$@D%5>1)2:D3*!6>&5<"3G>E1@C4!'F%/,))9.=6="6@)"3;*&@G<"2H'
@r3154
TTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTCAAACCACTTGTGTGGGCATGAGCACCCGCGNCCCCTGTTGAACCGCTCAGAC
+
7A(@F8D$52=*!1(A>+-5)F&#:D@C:B(<,#77F5-'6DD23;'6:.;2)!&@F"61%;@>H%C.#>."7.5!C)")<"'>'A+(#E.>(1<817#E,5&171A3+**=:>C-9"G7+7
@r3155
CCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACNGACCGACACGGTGGCTTTTNTTTTATCCGCAGACACCGCACGAAAGCTCTT
+
+%'"D24*!=+<3-/#>F?H/),A.7@#H&@6G,D5!F$-:98708=@#5'8+FA?(;@"3'A!,@E+="172=6F8D3A1(<E>?---F70EC41*5BE;A?,CE+1C**2)2)7*D4)$C/""9&759<*?+),?;GG6>H:&0,*G$H"5'"0*$0G4==((!3'-'$@B7H+$@(%'5+%.<,#30D4@7(.9-/#C!+"$*CGD<+A!?&
@r3156
GCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGNTGCTTTTCGTGCGCGCATAAAATACCTTG
+
69,3@72-*B/9E?;DF.H13!23!4'!'57+:E0'"+;;C:1(+>)A@1#8@447)6-;?6<)=!?<229/&0$:1*B(2A,(*HC2C9(7>%5662%="C5?)"4=18!B(9,,GC+--*E@*?6>.@"+D*"B,36;AA9
@r3157
GTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATC
+
G@'*=8/6#8D*'2-')F85"?/8D0D"5B1.=B//H>@%'?23GFDE>2=A2>(@D$-#F*$A-7<#%/
@r3158
CAACTTCTGGCCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAANCCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGNAACAATACGACGA
+
-)#%GD(58G;/41:A%6,F7"*!7#/5E7>CH$2>$E.DC1C)!31!F$:6!*;&E4ED)"';1CCAG0*44>=A<9/2"1:9=%%F".'9,+66A<D'::*96+-+A62>&9AC>/%;H"7,#<5<+:%E9</:0/6!(7!*/C*+%?0E:#*?-3!/?H#.H#%78:E?07$4E$%;#,-=;?G!="&AAD?9&@@(%G6,<7@+6&6EE8HA.)#C:0=#<>3-"C-!=F,*F5!
@r3159
CAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCG
+
3D.%"@220B,30*0A2"(&2G'B$@>'G7A*GH/&F1$4/2(,FC3>;,A>9#)?*F<A*D7#(E-EEB-H61#??9<C=7B&@,$C2<F;-(6-@$*7)B@8=?!1+A92E?@A1..##'*+F<DE"2F)(
@r3160
CCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCCGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAA
+
/!C+91F-/,#=$4!B,4#/)<+8AA5,4++F?D82(;''#<?"-@:.,)+1;%!.D;3.-):/6$+7:..2,E$1;@<9'"!C7>F41D(9'(09+==BH$B9'D@7@"?3?FH,AC*,,B/
@r3161
TGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGGTAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTC
+
(#>F<(73:*/$86=1,$='7)%-FE9@<0?*#D/"332"4:&(#G"D,D?&$%!<0?7)?H>-#EA@,;".-C-6'*6#(1@-2;27E#,>.*!AD*A/!?"4#F7C4F+DD$#<4A"1?E?&C0@/?91>2C-)(37,B(0?A$%G0F3.@H--,AD/0?0?E'5&DD9A/?$AD:7-'#83G05<-#C:/'=#,6%',G@"!CB4AGA*"?0:(/F,,B==*F/>2B1H@G1/%B!'?A:6<H.?>:#94$,4&3'#4B%D?'<H.5C3%6A4&!)+B3)+E'-==AH@=7E;+@CE7-C4C><GDG20F3;(5@F<EG#?<@18B37!2*:=@;4E14&1&$8@F,%BG
@r3162
TTGCTGCATTTATCCTTCGTGATATCCGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTCGCCAGCATGATA
+
F4!((#C4G7B0(5'.0-C+%3.,2-C-4+"?072?=*.:DCBE>7!;/"6CEC#AB-H;:$<BG$?-@>(*4G)&C=A%D/H0"B=;3.@5(7(84*?$0B4$=+B%1><4@1>GA0)%:.>
@r3163
ACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACG
+
;:)'B5+$/,D&!@C)#9F1G=;/.!6D$>#6-%=.D)6G$2AC%H4:)<0&**@.22/A)9'%,8;B-
@r3164
CGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTNCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGT
+
-(:E34B!,%117!1,$&$A-%4*,$;3?*;H"BHFD84H?$-09:)%4138+5!G8@.B@"55GF,,DF!57C'8E!EHE7#>*!/
@r3165
GANNGAATCGGAATTCCTCATGTGTGGCATGTTTTCGTCTTTGC
+
$(""+&#*%%%!$#"*#%+#&&*)"%&*%#)#$)##(*##%"(!
@r3166
GGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGT
+
-853+@G1$1"0>6?<B94F'&*66?37BB4>($@:0-#=#4?-%:(%CF:;5G/7E)/"9$G;3@#B&&>8()35,A%+A?7;+#9C0G$=51)E-9;9BH:<<4$-=91D=D@C<=*@GE8.3H=B8<:)6D800C@2%7>!&F8!D+(;A21!9&'7%1/*&@ED8H73'#1"E"8C%*45%:&<@91#.CD4@--13C/A$0'+.',;
@r3167
TGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGGTTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACAGGGCGATGTTATTGAAATCNGCGATGATGACTATGCCGGT
+
35D2F:*3<"A5+)0;%665"G>*#1F&,$#D)'A:1&$<8@%!H0><=H(4C08?0:,1E'B8E@2&+":*,&(C$?D-/6$";*.!?62F$-&!;8)369B(+(D(3BG)$&*&.);)D1":1):/89$#50$.%6G($3:;H/!6CH)@E
@r3168
ATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCA
+
90%H03*A6%!'F/3("37$7F@3&D&"#A01.7B":&GA8=%:<5*&DA/8;41216D!)CBGD9-?6;/7!<@F;H5=F6H*$8
@r3169
ATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCACGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGT
+
;1$#-+4<-B@%(@F&/@,)+@7'$.;'G40!G)@0&ADA4DE;D,#,9:5#C*/:+43FE3/:(&>7(0$.,F@#BG&F44+G<59=)@+,BH&3/'%6%4+&A%8>1(62H(>5'H.E1'6..*;',"
@r3170
NGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGANCTAAAAGATTCTATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCT
+
%:&&=:>%1#<8./DA95<?+0'E#E?.D:1&>+,>+&H17G-(9?145/E,>$>FG$3.$<;67:+*A/,1G2=3=2BFB&F%0H:<!:,5&#0!"G7CE"0BF-+;E-DCH+674$H,
@r3171
TTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGCTGGTC
+
*6C=9<FBA<:H0,/G"*0>:5!0,D@G)'DH<$<'@?8!35&+5D0',&:?,4.;7303=);C/$B0B%=1/&7-03*,C#G;+%$
@r3172
TCCTGGCTGGATGCCGCAGAAATNGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTCCATTCACGTTTTTGAACCCGTGGAGGACGGG
+
C7D/FH68A43@E?%0#:5-"$&D?/#4&D8'2+.?")4@C=,G)-"+'(E35!A%4/46#E;&>7,**)+HE)(8A&E,&")''2H"0!1"5"$9$
@r3173
NATCNGNCGGANGGACATCTGCGGATTCACATCATGCTTCGGCTTGACATNTCCCGGCGCAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCA
+
"(%$'%%)%#&#'++#'&+#**)++%!+"#*&+"&"$+##*&+'$%#$#%''$%"'%+%(+#$'*!&+(((**%*($$(%"$+((*&&**&)(($*#"!&#)')(*%&'+"++(*'&)$%%%"%#*'#(*%&('%$($*'
@r3174
TCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATG
+
;+16;G3/<*?.(@)/8&HAD#9+=C-6B'!.=1@7#:$9'!G.6D+.22F,7H1?
@r3175
TGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGA
+
)88)"!$G7B2$,C5@$"*3D>>7$1.@8,&;F$47-E%*3-G359$$:))D+H(D;3*--B1#4))A
@r3176
TANNNACCGGTGTGTGCGGTATCTNACNGGGNNGCGCTTTGAGCANGGTNTGACGGACTGTTACACACTGTTCCG
+
''!%'$#**#'()(!&'$"%)))(%'*'&*'!!#+)*$+!!"%+&$&$!')##!+'##&*'(%*)!$&""!)()!
@r3177
TCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCNCAACCG
+
/8@E3:/1'+18%7'@45'$"'2>-CCG3.:$#&HBE/+D><%?5H
@r3178
TCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTCGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCAT
+
4(2=+=&H?4#=1B,@8!C:>$F0F8FH$?#7=<*;"E(3A0%8#$,7G<>G#E+B@#60-3:1:<?@6HC&--(3%!AC2HA(F&8@A#=03%7"('2F?F.3B.+;>130;>%$A="';A8%1HF7>/;90<-9
@r3179
AACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCNTACCAAGATAACGCGTGCTGGTTTC
+
H(!?8F(//5F&A-%H"CE;5+@/A&2'!5<5<.,?B7;E;&B7$701HA1=#'F=8G?7?5F)'AB;%GG->AG47;8<%G4@C/08,FCF55";-HE&4;995!1>!5(7G+&1)-%C>B6,#6B7'<B<*'=%$220"!H7*"+//<=+/>9?7H'H(#74A7181)+*"//<.@+2+G>#7"#?#-++0BFCEH:D+B&#=@=&6C8C33>3@"927#BB1+##C5%&D5$'8+/#?D9,=17B7943<):(2+06%76('+
@r3180
TGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGNAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGNATGTCAT
+
>7CE'B=;%&F80%8?/;&D-/FF%;D'B",.:E?**5G4,!$)/>22=F;=%7-G6B9E$D,F@F"%B,(2+CG76(%2AG4)?B16?6("514=C>!4"2F5?H?+94$$&4!;*5B4E"E2%@F=:<.)#H.E;9$,E(#H'.B"2G?AAA2%4;)@H;#46A%2BF"(#EF7'($#(:F182F;>G+DBF@'!833(D((#-53;157#+&3F-<DF$.6%>/A?3-$?C+/@9F(
@r3181
ATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTT
+
)#*<""1DD;;1*FCHFC(&9<<1@BE3#.<A<.@$F!(<7"*@<C,
@r3182
NTCCGTGGCTGNTGCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCTGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTG
+
)"?H@>*9C6*@'C4;,&0:(&"/D9?7+;CB:,4G5.2*/B?&<HB1C0-</(F*H/7=,="(BB*C>FF7'A+?%3'84!"64;H=B7A7@G*AHE@(B9!:($F/'66.1<"B&:"?6D=?4/;'<78>7G+2'(<ED&G
@r3183
TGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATNCATTAATAAATATTAACAATATGAAATTTCAACTCATTGNTTAGGGTTTGTT
+
@+,E#*F)6$D.G>0:,00D#D0+68*.+#?'$8+*,;AD)H':7?7+0;<D/-2,,-FG64*054"?*H8,DDC508&16',<(*$'A$6H<B#0<:C'"12%
@r3184
ATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTNCTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTG
+
.'70F$?@=G%,&4)G.002(5@2(*:+41?!0<!81">//4/1;,',26BF@CE'<$B.(08"D7F"-A:&#;!7:'8-C=>&"E$"@$&E(A=2HA-2((@'8?+*<#95+H7BC,&A36.D6A7CD7F8"*A3<#B6=5F56E'/H@E<(.01==50.$'/+057<,%)$-'*(+/3?GB4?-(<D%-/70@>>6$@AG)H3;;4"5D9AG:8F30!DD=@5<A9F@6>GC/;8?"/?7913,%C99,%2B4!&;;=(+F@AG888?E$=1))0@)E<%6CHE=>00H.)68-,?/G$57<5DHG:
@r3185
GGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTT
+
1G'A&9&8<@:9)+F&,;G$EF.'&<8+C<A7'92>;;B1;7"
@r3186
TGTTCCATCGTGGTGATCNCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGT
+
18DG8C6:"0@A8'941$=(0H849'C2>9@+-$=,8!&/1DD69>)*'/87;!<'91A/E;45H;E=/6E8E"E%>3!&CC
@r3187
AGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAG
+
/'2"4".*::<'C&8D#-2-?A4A#4?):4C&=')<AH!9AEG622?9C("))4)@361%/#A&36*&
@r3188
GTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCT
+
17@*))!>#*4A;+&@6?==97=)8B):C)'.?"5E5&+E$:.-;@66+#'7154#/4$!61?DGA0+2:.%B8@7#BC'00?1F3/?'H<41!
@r3189
AAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCAGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATG
+
/@1;HHGB,.!>:&+34==>B?:8%D1D#H,18+<E!F6'B!(;1*G+2='7>&.3F$55.1:4/(G4D;860E:#H/>D=C/'=A7?,'?,>?!EA(*FDC%&<+::;08CF78+4A/F)-.(H67*3==3'->?">@A#,:<$/)>,!1?:0>-.G5G"D!;=*E6#C91&&"'1+7=F2:+12.0E'&G)&E40
@r3190
CACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGAT
+
!,:=E#1873-&;EE>2"73;::8F0%AA8397%6C>F=0"(H#(()<E"0
@r3191
GTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATNACGCAGTCCGGCGG
+
G??14=!>BD@*9"6)!),0:3%(,@E@61?%(A+;G?DA+;@@*87EF>5C"
@r3192
GTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGC
+
>,$>8=?@&BD1B3H#$/5C<>$$//<,#A.7!&$&*7!<:H)!45>1E2:#0*>*):F'@>G.
@r3193
TGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGNA
+
0B3&5=-,!76.H/B'B$-!<3F:+)B8$90/&>-+490H=H0,/3-#*DHH<97:65"7
@r3194
CCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGAT
+
"94>A55AB('4<:+7?*@8$8*3+-7B?#%=A+#*6&A-A"&D9)9BAD>81H)640&7;"2&%991<4#,B4<8)7%3
@r3195
AACCTCTCTGTTTACTGATAAGTTCCAGCTCCTCCTGGCAACTTGCACAAGTC
+
AG,/;,-;+5;%CF49;)GE"B'48(6$G)D9EED*A95:E47::2>;8'0>#
@r3196
CAATGAAGCCAAGTTAGAACCCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATC
+
24*D*)E&/?4B7$00(1B/9!G,?9'".?.$B);1:,25'*&?(&BE*D-?EC!G,E$);70*%G2#4+CEF--E>88
@r3197
CGATACCGGCGCAGTGTTCTGCGGAAACCTANCATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTANCTAAATTTCATCCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCA
+
G75*1G$H8B53BC?>!8'51EA)EC+EDAB=?06-%5@6G,)'<:?EE2+-?D?@/!)EC048)7B/=G@37+@B90830;&$8)>8,=!&9E)&HG9',B3%,:6GGA>75H2&:1">4*64<+3"14,.92,2E!EB!G!+==#?&+@D;?&C:E&+BDGE2*9'"1%AC'.B2"*7F'E</9,=!#.27D7,//%A0-G(81&,&)-6;
@r3198
ATCAGTTCATCTTTCGTNATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTT
+
GH<%A8/3,)@H<3-/8(70:G8,C/6"F?80#@'?$;.&89<%+:2#BH8C3DGCE(4"5(<94@BF!!%;D
@r3199
CNTNNACTNNCNNNGNGTTANGTATCTGANAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGA
+
'"$"$"*!''&"%!&$(**$%()%%!)'*!)+"&%%(%"!#$#$!*#*!%+'!&+('$&$('))!!(!*%')**)%#&*"**&(*)%&*+'!%%!&#%$$#''+(+'#+
@r3200
GCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTT
+
'98'2;7+/5#220G(9H7F?4F)E-7H#B'.FC<7<D;H1$GB2>A'4::9A$G%0(F&9*8)<"7/=F6#!6BD
@r3201
CNTGAGCGCGGTTGGTGCTGTTGGCGTTCNGGTCAGTGCCGGACTG
+
!'BE.G%..4E;:A728FE40(2F<A<&47G3+9E@!B=<@;61!3
@r3202
GTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTGATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACNCATCAGGCGGATATCGTTAGCCCACCCAGNAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTC
+
#@%9>:)"D71+3$#&'+<&)F3!45H&$3<D88@F>&B;-BF(.-!(.E@*!:B<05&F')7=(H.$1"<(6>0D>3'8FCBAFFB*//E:*D#%7<BG=2/F5/-(&##<!#>;AB+?6(2):96:7G4'7.+:H%'88F$D?20)F3;3<-"823*C7/D5F&;5<&18E"A@*H'213#G"0!@F9%E&+!>()%G!2:><H7+%E"8;AE=4D(:BEB+3B2H9H#@8<&,089HD498&'H$G+3=
@r3203
CCGCAGNATTAAAGCAGCAGNATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTGTGGAGTGG
+
;4+@.6H5&*0%%)#FF5*A=*>=E-H2:/!5!0->-.#=1-(&0H@GE@%#!++#%)0*9@G)5.,/2)536D2*&A#4;05B>4*H-=D6C/2GEHG!C)C$=58>7&#"@E(%@!<A%/?:B@61-32-'-%)"G3?)0A3/GAD)9=D+(91(6G5D2H1?B>,8115/F?.!6.HH9
@r3204
AAGTAGAANCANNTAGCTNCCTGNCAGTNGCCTTTATTTTTGGCATAAATAANAGAATAAACACTGCACTNTGTATTCATTCCAACGANTGAATACACGGAGCCATGTCGCTCGTAACTAAACANGAGCCGACTTGTTCTGATTATTGTAAATCTTCTTTGCCCGCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAANATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAG
+
$)$%#*%*#!$"!!*%%)&'#&$""'$'%+!+#!+%&$"&&+#%'*'*+)##((&$(+$&(%$!!&'+'!&%')+&(&"!%!*#*%(('#$%'$$$!#(%""*%(#+#'(&#)#$*'''%!*'#"($'&(!*!()%#%!$$#&)'*"$)#(#("*''%$**(+#"#**)+$"%&'+"+%+!$$!($'$!"(**$"*&+(&+$+)+!)%")($!*)#"$+#&*$'$&*$$""&&$$(&#(+!&**$'&(+"!)*!%#++
@r3205
GCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGAT
+
)7)F7%)3,#5/(3249-#$(5>1(1"!!7F#1H32D6957E'4C:@!351&CGCE&!D3=0(BCD)5!DE'/()+H@+D67764B%$,'?$07A1@6G>D?
@r3206
GGCNATGNCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTACGTCATCATCACCGGATAATGCCAGCGTCGCGAGTG
+
&(*!$&$!"*+'$'+#&#+(%"&$"*(*%$$&+((%&#$$'*$&$"*$(#%"$*&'$+!"))(+#"!&*(%+#)((!$%"
@r3207
AATGCTCTGTTACAGGTCACTGATACCTTCTAAGTAGTTGATTCATAGTG
+
9AB">)FA3>"+;A1;')8F$+>.H(%==?;:0A,1@3+HB:D2(3;"4+
@r3208
CTTGCATCCATTGCATCGCTTGAATTGTCCACACCNTTGATTTTTATCAATAGTCGTAGTCATACGGATNGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCT
+
9#069,!)9$='!1!1!75!H+D;78508G*$:%?5.5E:18"?2.A,G0E0<'82-0,0>@.'D:G!F/!204@8B.!&04%34<H/G86/@6A%*>)2#9E)D0'*.5#(:#F(D3?+B5=",E4<&E+6$'1?HB
@r3209
TNCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGNAGACCTCTAAATCGTGCACA
+
A9=+72"51!)@3C'&G)%+!'E1?A45%5-)G@"DB,.8#)#EC>EHD1;;:@<H?#G+:1DGB"3:;>DCD082+E-F>?-C+($'FC4EE:
@r3210
GGTTCTCGGAAAAGCAGATTGCGGATATCAGANAGGTTGAAACCAGCACGCGTTATC
+
$?E@:;($H+%A+?(6!.:(:AC;1*/24.@?,"AD44+G*@*F#/0"F=AG<A)G8
@r3211
AAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTNTCCAGACGGAATGTTAATTCTNGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCA
+
7)#;56//3<D.->!4>!6")D<<4&C.,*+<G)1C=#9B4+$"1&E+/'H36+9-G);6;26&#423/AHAB25::#('4&354G;>>:>7*2A"A/H?AD&*9C@.?C*,A9&0(E8&!2%/<?$#B;#"%;=/40+G;'@0F*>EB?"++CF#64'/F0AB6)77%6%!<D'%2DC7((">8>C3<,7>6@HHC::0:659&3D-'<)3'4&6/,702F6H*03=:D-/14)12;1
@r3212
CAACNTNNNGCCGCGCCCGTTTAATATNCGGATGCGCAGGATGACGCCNGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCT
+
#&)$!$!#%+&+#!$#"&'#!***+"#&)')"%##!(*"!#&(%+#+&%!$%(+)!''''"#'+'$*+&$(*(*++))!(!&$#&!'+#($("'!%"*"!%%"%%)*&!))%'&+*#"!%$)$#!
@r3213
CTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCACGTCAGGAAGAACTGAACAAGGCACTGAANGACGGGAAAATCCTGCAGGCGGATTACAACACG
+
<!*H+<.**E)1@104/6<E0?>-H3,(G5-?*@3F36@2FEG$,D/""C7?D.0>4C.#"%C55"9'-#B&$$B66''6<555>=H<=0-H4)8EH<4;>@)</8C;?H9C1!?B"(1@8A.3-+?&FA:H6+'82=AD!,F@697>!G)/,)0'3'4/0!48$B.G6F(9-1E>7FD4*/*HC*4&9:(AC!A;1>4>"CG!$0E9G(#+;>2<
@r3214
TAGATAAAAAATTCAGTCAACTCCCTGAAATGTNTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTT
+
'(+#$$!!&#$(*&")%+#!+#)&++#*$'"++")&((#')*&')&#)"!''&%*('!+&*&(*"(%++%&%'+$(!&%(*%+)((*$&*'#&*&(#+$)$"!(#$(!"+)+)*$%*#!+!%#'&(%
@r3215
GAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCAGTCAGTGGT
+
;E/H%1-A-;.B$-'*:8,')<-+8*HG?.7.'D@G>C#*"@?+@:@'"DH-?,8
@r3216
ACATCCTGCTGCTTTAATGCTGCGGTAAACANACACTTCCAGCTTTCTGCATCCANCCAGCGGCCATGCCATTCAAC
+
.9E1E8"4D*B=12E(0.&#:?:3B31H3!FG&9"!.1E4A@B?E.F$0?%(')+>-!9-"8;'A+*-*DGFB=!*,
@r3217
ATNNGGCCGGACGGCANGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGT
+
(%&+&*!'()&$%+')++'(#$"$$++&)#('*!'$$*!##$((#$*&$$**(**$#!)"$!(!%))()%$$*(+*
@r3218
ACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAAC
+
<+/$BG#@3;;B-<B8?*&-46G</C(8>6>@(:$9B:9)8B,-C,-:A2B,03+;6D#-*,3$=@#1!>:4BF(F6>&BH#DF+57?5&
@r3219
TTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACNCCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTNCAGATAGAGCCACTGATG
+
4F8#+F966G@:40(H,%D%+*B7B6G:0;.5@()C3*/*F0A9*;?>H$+(68=;AD%F1F,9A5%GF!+=,;19,E6(D7.4?)2?;=GA>+-)*:B9$=:%)C32(.@>A3.2*19$%:'6/;3(06;)%18:H.4E#9;>"0+5,&C&G
@r3220
CTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCC
+
3?+@<F/;)EEG**?3.:G9+#"F/!",E#&-),6="'/>)4D2*,0C8&
@r3221
GGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAG
+
A8:??&'2!8?"D02B297;E6*@,!+7E(&2->E?#7!#86%<*!+3<!'G"50395;$$%)/<
@r3222
CGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTNCTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGG
+
F=<+A>:4,!C!?(B?;-3&F&$""B,/)F*=!:9:()-#?)/$F3?2-5D:?<"'8<E/#(<>!HG5<=F932$?(7A07#4B2(8)H5<$;%8*.!8+0?C#6:D;'-)=='*.8.@6@>,$C6"/>#(=%)7+@<*D%0?B+H
@r3223
GGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACTGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCC
+
=?,'7H1:"9"..':6)"G9-&(2),0#@B5&"$890>-/,#*F=3/>*#A2>D!'";1(<!:>:<>F:$H>:4(3FB%GHF*<9@':5H$88H(0633E("3H78E:E?0<5$(4:6?0"'1#(&+47D@92B<"D<>=E$67;
@r3224
CCGNCCATCGCCCTGNGCAACCATGTTATCCAGTGAGNAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGNCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGC
+
*#%$#&#'#()&&&*$%)+)*)%$#))'*(*')+!#)$&'**')$*$'!)+!'**%((&%!)("()#!!%$(!")+)$+#(%"(($!$)'%(%!'!*!!+&(#"&&%'##)&%)"+)&#%(+*!+)+#)()%!"('*"$%*)+("'++*(!'!'""(&+&(&)%+"("))$*"#"'$&!+*'$"$+"'+*(*)(#
@r3225
GCGGACTTCCGACGGATTNCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCANATCCCTCCGGCGGAGTCTGCTCCTGCTCACCA
+
%.<4H"D(8'#;3B7$9E!+%,>C>/G;&.-AE%E?5H40!9?4,14444)7*2-B:%6-;!;@H-B@7$%#E9C=+4;&1&(61"F<G:A$!35A<-0%.!/()B?+<H"-/2E)5','?!F!A!+@!A@%G#&)0F=*B3F7'.3;"6457C0CB$13-=.,8DHA,ED!-="08A':G#D3H.8F")A'"3'7%A1CH
@r3226
NGTGCGTGACNTAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAG
+
!A4<#7%8(,59,.:,GE2"?&"AD&D,8%(67H'G5-F.C2!E1C4&0E$G58<#
@r3227
ACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAANGGAATT
+
#:%<)4B$E7A9GA%D>7B3%!7:<++)9#+'F)2;63-!78*C8-(+<0>!/8;FF>BG.F=
@r3228
AAATCACTAGGCGATCTCCGCTTAGNATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAA
+
*=F%"E#-$.2/!5="-/!*$)4G#=&$D4>3E1;-8/4F"(G"507::DF8#/269/+96)<-$G;4
@r3229
GCCTGTTAACCTGACTGTTCGNTATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCATCATGTCGGTTTTCCAGTTCCGGAAAA
+
@BF7D#021'<D5,;<F:;<)?G'%0%1,!9):CF0H,2$<7,>H5D3,'0.#;)?856*%GCC=?5A9.9<?-.G%F9<C3-C7)4!;%))&3,=A/G+%/:DGFA=A)'A47=10G.0*9@$EH73.?*3*1/
@r3230
CTTTCGTGCGGTGTCTGCGGATAACACAAAAGCCACCGTGTCGGTCAGTGGTATGACCA
+
<&G<'/1);F<-C0E64#E=*F*:DC@>'4;GG37)C$,+3),,E?0GEA&(#F)0-?*
@r3231
TGGTCTNTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACTGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAA
+
:/94."@H=C)76E3)@?:;=13)&DA0:8'2=1C33.660#((/<821.,1)).:H52(;&B'0)$#(+.A')'$60&4==-?H.-&-AD!4<+(&@86?(.F"8%8.>H.
@r3232
CCAGGCATTNAACGTTCTNTGCAGCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCNTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTGAC
+
(;H"-E)#BG*-@H+7H(+&;5G#B'=2@@*:-0(9CG7H!,EB!.G;?C1*)+3+*>518/=(#<C623E;D4<';-05.=1=/!?$+#=+(C6312-!;1*69?)0G"-@B8=4.C;6%=!8"!B,;>=H6$//D>@7H!?1%4<5!%15:!B85661:#DE$0@),3415&48F3/6'+2$6@(39A:)&)+:
@r3233
TTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGC
+
8/:F9=C)C(73*"'$)'H>/!1BH:32"+;!.#@<)<.DE'74:(D94;1H!?>"8:*5.G)='61E8G90$#%&?%FB9E8A0*+4H!$$$E'D</$>#2G.#7E#>D/;1&0
@r3234
ATATGTTGCCATCCGTGCCAATCATGCTGCTAACGTGTGACCGCATTCAAAATTTTGTCTGCGATTGACTC
+
7;;F/?$G#B@67*&C#E"&ACD#-=8C%C4;,/78;6D89H-=('+,/;?65;A(+*/25).E#04D=4,
@r3235
CTGAACGTGTCGGCATGGAATCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGTGATGCGCAGTTCATCGCATTACTGATCGTTGCCAANCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGAAGAATGGCATCGTTCCGGTNGTGTGCGTTNATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCAGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATNATTCAGTGTGCCCGTCTGGCCTTCGGACTTGCTGGT
+
<<E@;:*34"-H263>!0E$8#A;BH/2$<76+F+B*"8532C(E$42$?56H'22FC+(<<4=3(%7)?/79(@.B)'5<#)D4DH9F,2391?(#H<C+A5D>F!9<>."BE3H2:$@!@>4"1!(#*6H<&F'B$6-$<A&D:#/)!?28)$B,D5:@9---A2,,/=)+>F5?1/F?5=,)=,;#B'%/3&:-8>F;G131%#9!@C78@)?:275C">:-#G1FC"7G5%=+AC7"*->252##3.=B7+:B8+=E@:'*(;<+/?@/%3&;@-+1G!6;D:<E-FF&;C18&"-+CE3HAB2%G%%+G%!B#*+)72+@F28E>FE@94.?&9>@/)?,1"&(HF3FDHF8"H@:'&'7%:?DB+:FHB'8-4'8DE:,".-FEC*,#=#A0/C3627G4C7;?4HH%&%CG/:C;.4+'+?EC2H#C5CBG95FCD@<C2=GG'7=4CD)*>+;8$./<.
@r3236
TGAAACCACTCAAGTTTGCCAACCAAATGTCTATCGATACCGGCGCAGTGTTCTGCNGAAACCTAACATTGA
+
?/1$!4$$'%+>F1">#46$BD+24E6E?2E8D(;;1,=*%-H!:4:,/"C/7=$.-FH")43)<)GA;%$7
@r3237
CCATNNCANCCACACGGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTT
+
'*$"&%%*#&(')$)&%%+)&&%!+'"((%'*""&#"%"!'!("%+$#'&&+$'
@r3238
CTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTNGATGATATCCCGTNTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCG
+
6;$$974?H!,$-?1,:+0%4D;4..!+C!/+.07>7)?=39'G4">#%AEBCF0.#D8)9B(H=7$98E1/DG38@<B/H$F8&),+=:F,,F5E3(070E?%>EB9>,
@r3239
GCTTCCNGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGAGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGANGTTGAAGAACTGCGGNAGGCCAGCGGGGCAGATCTCCAGCCAGGAACTATTGAGT
+
")&*$'"+)$$&$!#$$#*)%('!#*+*%+#)%*"'*$("'')!'(%&)!!%("+"+&"$+#)'"#"&#&%)*&""++)"%#+#!"'+&%*)%'!**##%+*"#*('$"($*!(**(!#'%"%%%#(!&)+"*#
@r3240
GACANAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCCACCTGGTGGTG
+
2#>?8==%0,2<E57DB(;>3!0F9@4>)H-"2E"/:E*F2?)C8,527#2(02?#"*+<>D03B!8!>H3DE0E8;;9!&)6AB>=*D%///0+#A#&.3
@r3241
GTCAGGTTGTTCTTTAGGAGGAGTAGAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTANCACACCCATTCCGCCCGATAAAAGCATGAA
+
1*36=1;(GD&*.A36F55$=+,9GE89"=40)F*9EF/HD?"F126$5A1=60<-5*;/,$3)$8B/HE3;*&1(B><*&F0@%?8!@351,.EC2;')BD%6%B+C&78<F7-6A/-H%2*3FG9*''>)@'BG?<FDG8,((%,83)56HG$/:A2'72B(A&0G&8*/B(.0-!G/"?-!(;3A5.F3!!GC>8!=#,1;(+619
@r3242
NTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGGGGGGTTTTGCTATCACGTTGTGAACTTCTGAA
+
'D+!@1?BH':>:!;472+B%<B4$&'+E4%/:4-C55?"#F:$9(""FFG#!)018/HC5C&C"90>;%971%((95
@r3243
CCAGCGCCGTCAGTGTNGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTA
+
'7+H.A&(@<)&)72,*C0/F&0>2.:;/<<:@B1:D&B!);>98'C/D@
@r3244
TTACCGCCGCAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTANGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGT
+
A<A9&6;!7H.$G'A)E-%E'D671G5268(+<0&=;$8!,?10G3CF/#;94/H"C<'H1/$852*F,2@'<5#/F>8>%:.'$;?D&@>5:*DD0B/('5G2+74B'D-9BG+<C%=7>F!C6F0.29H",=F.7'6>-3#!E0(&792<<*GF?E41+
@r3245
GCCACCGTGTCGGTTAGTGGTATGACCATCACCGTGAACGGCGTTGCT
+
:$'6911;(EEF"6,(E7=!2;D+E="@+3@:&$:005,5#9#7B.)&
@r3246
CCTNNAANNGTTGGTATCGAAGGAATAAGAATTACCGATANCGATACATCAGGAATTTTTGATTCAGATGATATNACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAAT
+
&$&!**$$$+&!%*++'%*%&!!%'"%+*$%&&$"!')#"$&+%"+""'#)"')*+)*"#!$%#&%!(&"+'"!$!!#*!'(+"'*($#*")&(*(*"&+"*)#)$##$)''!)'#))"&++(!&"")$$#&+++#%+!%((#!&%+"%#*#)
@r3247
TGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAATCAGCTTACGGCTGGAGGTCCAGCATCAGCGGNGTCATTGCAGGCGNTTTCGCAC
+
)?!"2&*<8!@>&HG?.*)%(0C1#9C)7B'#F+6.!%3$32?::/*56!7D=13*260G!>C44.&/:B<F9H?-",09526D>+CB*H/5377)71$A(*E+H-?(3-GG7+3;(1;?2E.%:C4:6
@r3248
GTGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCAT
+
7%;)H(0+!*9!*BA47C'71=:7A,?$/=8+-?:6'9'#">*6'CF7.@GHF%
@r3249
GCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGC
+
HH*$22#H5&#/$.<2C43(C+,;3$;@?&6!?1A?C;F59:$6&8GG2.,(AA"&E3<)9%4<&H,-5#2>=>F>.';/D*45)?";H)H
@r3250
TGCTGCGNTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAATATTCTTGCTCAATTGT
+
D$;##E$B"9F&96-)GD8/$?5EA9*8;6?'&D,%A0D77:!35:2,9=)0@661=?84("&/((58&:*EG76D;78:02)7%F198F%70B&<EC$0$%@3+%&/1=E)
@r3251
NGATGGCTCACAGTAATTACGGTGCTGCGCAGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGG
+
)8177?%B"94$F?:B:E;<+;?;!73HD41@7$/0G;<44>4A45$@$&GA@F<H,:<C;&2A;4$+:?-H@68)!-$7,<5"?:;HA+>)<5,?93**(A703+?;613
@r3252
GGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAAC
+
.%)=/>;-)5)(3>C#<=<";GA14:(B*+!1A83<A5.+/%%HF"9&8:4E?E!,C'#-!!A-<H$5E/!H=2F",*.$.9==5-+DG!'-@3<D@!.)180;
@r3253
TCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAANTAGAGCAAATCCCCTTATTGGGGGTNAGACATGAAGAT
+
503*7"0G!>=H?:73H.1B/'D6*C8G(:34/F@03++E215=8*11(4*89G#')?E#;)D.B+%.(<>A(90<0E28#7CDHDC;0%D5A!2?;D(!-B
@r3254
ACATAANCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTANACCTCTGAA
+
#*%&**"+*'%#!*)+++!'#"#)#%&)##'(#($**%&)$%"'(+'!"#%#!&*&&##*!(!+'(*(#$%#)$&+"+('
@r3255
TTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGT
+
/,)>$*")0!"?@4+'2:A32"56'>6(#:4,+E'@>3"EE-<%3!C-3/<A,D-:$F&C'
@r3256
TCACGCCGCAATTTACTGCGGCGACGGCGAGCTGNNGCACCATATCCCTGAACAACTGTGCAAACGAGAGAGGTNCACCGACAAATGGCAGCGACG
+
&8:G#F9*35%)&+0)*C<-"0;4B7,'<0D0%'/BC#0>0AG%4-9488.;+<DF$9C55&<8%0D0!533:<C@<3.2#0.<84"9+EC4(+1:
@r3257
TGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATAT
+
3-<C"&E@-(+';(<$'.68-ACH89!)GG.C<@.-<1CF7C>E5(>%F1G4+H!39B?+.:-
@r3258
CCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCT
+
"*,+0#0H@49;#BG*A?;9=067>+8AF#%2AG,F)23DD;#>
@r3259
ACTGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGNTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCAC
+
&!/?AD237B&?1)-%$?<C280&F@:4)(9($4&?G8&?EF/0::6FE-94C8(66$F/./;+G*(B,6&;B+2F%@@'AF<54H889'?0=%$D$;?:D(D/58#"!>E,,G*)FB/D.,;?2*:+9&4:%!F3;G@;=-?<B.E"FC2=B89@0B80:#$0)$D!'G)G;6BE1!@2)/1#'3C.5',4"+$BF$:"7#C+%0
@r3260
CTGCTGCTTGATAAATTTTCAGGTATCNGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTT
+
**>B7&E$-;25=*6;00<!#,B&D%&)A1@F07*3)+B:5?A)8-=4*F*F'CB"D*,+',9!#&(C$DH3?#;?@)H<5H6+9/59EF=D%#.0H'4<@=##-57!6,239C.%*=15EEH?"#!%H*<3)$=<;HD3>-4
@r3261
CAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGAC
+
H4?$?<)A.>@.G+-<86G'4>#?EA602!2C?:8(?*<3-7:?=F2':<:=""+03)
@r3262
GCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGNAGCTCC
+
D25&<GHE*%-5!$=)EB",8*'2$(#1;F78.?*A9(.,@85
@r3263
GACTGCTGAAGAGCAGGNCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGNGCCTGCAGGAAGAGGGTGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCNCGTGCCTTATCCGGAGAGGATGAATGACGTGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTAC
+
2>/F"0E*#G#8;C4'<=(8#3-G2D!C47CAF,')@2>;E#7;8G@*4.1!/0F39A78=)%HH85,G>&9D+<-?(=B1:A!3?#!H-<21=%%8;%"G=E@G"&%8<(*#?04.=CG:4/@D)/:""6#H8<6A10'/5:A#/9+0><6C7+2&&-:*08?#,5:9<'D%<G-,DB*)(<?!&CG5G+@&A%=H131?A9"C8B.(;%!,E4C4?B:%+?=BD9>4!H46G/<<$DD"1&2/G19E<F15HH:79'$0&+D9?(2;B#'40C<F5(&59,8##@8*!*/$-1C=9+3/1<+AD#'->5!;?*0:F5=*8@;DA9GB@2C(3G,76:DFC&15#7'F=9
@r3264
AACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGTATATTGCGCTAACAGTAGGGAAACTG
+
.G;**,'9C!(.$#:9$(@51&/56?.B!>$"H*A1FB6"*%;(!9%?E4'69EB6@'G3<GH0@#
@r3265
GGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACC
+
4:G8/"6+20H/D7@/#%'2&,5)E77,6?)(DBFBG(62DC;B;!+>#,&H*%>!)"0%$+D*',F@&9)**
@r3266
TNTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTG
+
$!)+!'!$'*(&&%)$#'()$'")'"$*)%(%%&'"&&*"%''$
@r3267
CCGAGCAGAAATCGCTGAGCACATCCCACGCCTTTCGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTG
+
>)+06-.'$3EC>G<(D9')9B+GGE/3D9H&+52;$91A)B.HC.>5;!@1.F6E$2,2:B';9G=:9"F5%<=*GG)&4H=F-(3=096?!@4;8B$7=,05"9
@r3268
TCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTNCCGATGTAGCCGATAAACACGCTCCTTAT
+
/&-5!.AH?4+A(;9!)+F(%7?B@-:@#+"BE/F0!9'==(!7%2:>=986?<)()#"0F2;=1$6%H*F"A-GAH9<@E$D6<+9B-F&6/
@r3269
GAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTG
+
/!>B8*9G!8E#76.0'EFC%&:#2(&72:,#E5B%4'9::/)@D3D#H&3(HC$+<,,1%6B%1%,=77F/8%.@*<;G*4A6%):G=HBDE4/4>,6#>$'BC(8-/<F;359?*
@r3270
NATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGGCTCATCTTTTGCCCGCAGGCTNATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCNTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACC
+
!.0D90<5(8#G3&*85H0+8F0A5H:E#4.*?;DH'9%#)8/0+(E),+D&DHF0;"#&8G!6+:1&-/7'+-2/2EG-BE:HG>/.$!G/$8F5HB*+<;0-;0DBB=H-:7*'C=&%'H$0B6&G-$E,0<=C4B9(C'3(H?#*#!#:#!45=!$8<D%7C0%..;)H>3@4>=69-0?(,B@"!(4-'.@1$H=F,C))$D9&7+@1G-%C5&E2)-95$:(B77*(.(:6:?<&6&7D$.=14G/>/760+AF0:?EE%*=%%&#A//,$8D95F><=DAC1G,#!62)%"5;()#$-!C8AH,C2@0/1>//<84--?,,4<?85F9,7E1G/EF/0.H++$9%:).#7.;7:D%96G3.%4<9$<!AE58.805
@r3271
GCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCCGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTNGCAT
+
=#*"!)+!3*<?!2HH->B'B<$5+(13%F.G%:#FGF<#HD47&"0@+>62*6%DG$F#&@!?>DF7%4/?D?<2!FF<3!++/7FHGF>F3+>/:=650%''.%*;0!:H2(+(#5%#!9G0!AA:?.G+6?G&?/&!;21>1!F8!GF@CG2>%
@r3272
AGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGNANGCTTCCAGAGACACCTTATGTTCTNTACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTNAGCATATTTTNTACAGGAATCAGATCCACGGA
+
@AC"(2-70G&:H4F+:$G1-+?."3003+"#906=)12':2':(!)F9"1/"<C5+"5/?F:5GF-A#;)BD=/(,;9<G*095#C<+0)/<3,)(*)E>2)"?E(>G<C03>;%*6"9/#GD)5124BA=9(+G5%?0,71H*F.!+@847##).F.4:0'7/@/%'B""73)B/!19./@H2!9&
@r3273
TGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACNGTTATGAGCTGACGGACG
+
1F8"E#F)!&!:2?97D!@9@4$5-+8)!?H/A;&%A-8F"?:+!?*C%@-"42E9(B#356'(>F?-'63%/4;+50:AB?".?&/4GE;<30,6CD;:<5E3<?F+G&B(6%6-<D1"H$H7)
@r3274
GGNGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTTTCGGGCGGGAANACCGGTGTGAGTCATCTGANAGGGATTCACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTTATGG
+
#)"+%%!)!&!#)#''&*)&'($!(+$"&$''%''("$(+(%%%"++#(#$$#+#"*")*&&(!)*(#*$+')&&+""&'&$'#+)("*&+%')$'$)&"#&#*$(+%)'#!$&$**)*!&#&!(#&'+))'(!(%#(#+"+#!%%%)
@r3275
TTTTCCTCGCACGACGTCTTAGCCACCGGATATCCNACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTT
+
B#%=;;E?5(>3;:9'=C&&6?!D!C8)CA=(*.'C-$0$6"/<F2'0A"1FHDB:"4D8:*B)@E%3H,:5".?3.#9?6B)EH.*H8<-
@r3276
CNNGANTTCNACNAATTNNNGTTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCANCCTTTACCNCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCNGAACCCATCGACGAACTGTTTCAAGGCTTCT
+
&"#(''%*%'"*&%**$!"!$)'$(&((+!$#$!&'!'**!(+!)#*+(%)&&#+%!)!++!(&"&""+%"&'%*%((&(#'!$)&))("$+&&#+'+$#'#!!((&$&)$%((#)!'!+#*)('(%"$&*'%(&%!(#!#$+'#$!+#*"+(%)'#'#&&"'+&'(!"*&"$
@r3277
AGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAA
+
.9G!+3CG",=1GD#(,&'4H&?GC$/"-)'D86E6++>H-.G'73=<'&1G3EDGA(E8G2F#->%=-+'B#C=$)=2C
@r3278
AATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCNGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCNCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTC
+
<"6)&F*>A=C*F(7+4-8?D.4EH;B;!#%45!)3.+8=A'0'.,>8$@2!8G='>&<H:!F/@DA"*07)#771EA901"8:/=?D&D)@&)'>2%C!%*""!E+/7'F)D@-70A!(F%@.';)/C(533(%7C85/G75/'E8"%6-C;>;GB9>B0?A.%)54.-#2..)%A<4:B667&B@FE%E?D9,(0"4??09(A:0E!*1=<3::.@6='4"EH1C$":%'C2)E."C;-D4#9E-:'DFD(G!$-'(<068&A?(!)D+$;?!(@;/-!#9(5F9996C'#40F(>22$1DC4,B6E936#A,6D?.A?&54$$/3EG(28-%(H>C0H5=9&"%C(H$%4+543=/$(<':87(@/E5@%<>,>97F)G4F,?:0'*'-6?"!A42;1F,(58+9.6G/,($2C1/F7)A/;B31-B*%#A0D@&5!A9=&<C!E>6%(.G$:9'3!(5F0(/+2,#G
@r3279
CAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGAC
+
)A:.=4F0-B*'+FF73-%D.?&.F=F?F<1/85F+H<5/.@
@r3280
GCATCATTTTCAGCTTNAGCATCAGCTAACTCCTTCGTGTATTTTGC
+
%B:B@/(5>#C/3;/""35146(@2*##-.%%):/?;9)F%6:G;.4
@r3281
CGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATN
+
AD6,A18BG(F)EA(H7>F&+("F>59)4)%66(@G"H@>%24B:3:H6@0%:H=',G!4"<$78(9)C5)G9-(")>@5A0163>H3;94A(#:4&F.?>('F)B-4/=+#8>."&,<9C-;#'@4#=1?@E::1+'=)9BA(2<(,(>5<C@
@r3282
CGATTTTGGTCAATNACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGNGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACA
+
3H%'+5&1>%1433$00>'-E%"2B$%"!6!=)"!&,!$3),:<:H7.3BG+.(C+?"+56BF+>0(C9@3E3.1&-D(1)178-3H21>C8B5E5/;D0%G)5BH1;@->*>@"-*8EA)3(.A#H7'F%''7:-CF4(-)418&%C4/;:%AD<,<#G9:3!(%!&E$#F@!62<F/C1F;.ED6.E),.A8F8*+6H.',-)-0F>4:B$3&!,7>=(E'#0%"
@r3283
CGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAAT
+
*65D)!>>#CD%G+!;$,*>4"+:F%:=3,==,'#$+?&"684*C&(+%<4
@r3284
ACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACGTATTGCCGCTCNGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGNAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCA
+
,C3/:D5#&@96B2E/4.68D'6D"0B=H5:-=$7)5G&9/""'98=:D3A?+-4C;**A2=%F#>0%C&G$9/+-AC,H<F;-)DA!&-@B0)C%&?FF*/EB7/9@;D+G!4"%;39'>=9/!054F+:=#!)6DD=6$<38<$5E5D9)%;<FG<C8$@(%C$4@">;G#95>G)*,3B4$);D;E0@)$:>&>#;&#&H7/D$-=6*+,8(H4<22:)"D3424?A@+1$92.>5-6,52.!;.'.),2B<-(@,'/2=%F"G?CC"7415$(34D,HDGH!5E7=./<$
@r3285
CCCGACAATCCCCACCATTGCCTGCTNAAGCAGAATTTCTGTCATCATGGACAGCACGGNACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTT
+
6"0.<7$169$H<=*G1F?DDF)!4B5G/9-@&/"D7,1-$9/D$(1),*)-B8E!-#<@4B:9B)=-D6-?'FF<B9%5"?)H9AHE/H%>+200+2)>.=>3GF!C9>2:>C2;AG"7#F37-;!*E58@D3A*0*>A?E-D<;9CC=F'
@r3286
TGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTT
+
<D4B&$=A:!9+/H;;+:+$+*&!;D'#=A'2.,=*-.3"33>B;HGG5C2H0C."%4,'*)=(,>HE%413E3G
@r3287
TCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGG
+
4;F5:>*#H#EAD!03A34"2E8@C,9(-E%'%A*F!)FD(#G.4C49-3,2#2D0E4@.'4#/A<7"/ED#<>,F-&(B7B(E&B0AD#A)=@6,F76-((?F3&2:1?#*+D24@,&D:!F3$H#2+9!B'H;>H.3H7E-')<5!E9A/86C$><F!A2+1)2D,2*?<;.8
@r3288
TAGNCNCGGNNTAAGNGGCNCTANTTNNNCTANANGATGTGNNGNCNGNCNNTANNNAGGANCTNNNNNTTCANNGGNNNCATCNTCATTNTNCCTCNNNGANNNNGNATAGACGNTGGCNNCNGNACNNTNGNNTTNGNNANNTTGCTNGNNNNGANNNNCNNNNNANTNGANTCNGTNATGCNNTNNTNCNTNNNNNNNNCNCTTGANNNNANGCNAAGNAANTAGANNTGGATACANANNNTTNNCNATNCNTNCGGNTTANNNNNCNNCTGCTGANACNTNTNNNNNNTACTN
+
#"$$$!$#"!!"####$"#"#""#!!!#"$!!!!$$""$$!!""##"!!""!##$"$$""$#!#$$!"$!$!#!!#$!"#"!"$##!""$$$!!$#!##!$"!!!$"!$"#$#"""$#$#!!!#$$$$#$$$$"#!!#"##$##"#$$$!#"!!!#"#!!#$"#"$"!!!!!$"$!!##!$"!$!!#$$""##$!"!!!!$#!!"$"$$"!"!!"$"!$!$!$$!$"!!"!""$"""$#$!$"$""$!$$$!!"!##!!#$!"$$""!!###!$$""$!"$"!!!!"#"!!$!!"##
@r3289
TATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTT
+
1,>/H0>F/B36E<8%61-367-8E;1!F+<A-B*:-775!,GB!/=E<'%!2">6?-,'78D&:/D:
@r3290
CNTNTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCG
+
)!#"#&$')&(&*+$)&*%#'!'&$++%'%#(!"+)#%&$#
@r3291
NATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGA
+
"H*/.*0;D=D"7>3G4+AF1F:CG?>G=C2,#9E#H19:G+B)D9B(B?*:
@r3292
ATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGTCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCGCGGCAATCCGTACCTGAT
+
>1/B96!>72?D-/:C@:3+A$4B"8@":D11A@29AF3>6=/#4D#G80#C4H!"'*&A$G;F77(59!=A$4G31028"60'?G:/.:?0@?$#+757H$64,;'*-"#.B6;@*<GF,<38@D"7*H66+:*%>=A>274B!G)G4/,@9$F71G5$21,@B%7@"<8$H2/FG32'=/&;A%?4!11B25=>:?H>6)H!AF>)*BG"%#56E:6#@"%(@A19A&B;=
@r3293
AGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCNGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCC
+
C)BG/;A:<'38$".=3=,4$HF'$"8=>27;$E@(67''B-:::59=)/'76F6#B<+355+/4.%*%%C:/%-&8.@E0,9E>#8/+D=3>-CD3;!BE<2@0.07/.*87?7,731-961/><%3/'=0F)A-=,+@4.%@8G<&+
@r3294
ATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACNCCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCT
+
**/DC==F!8"BHE+:B2',)"+!A%>&G?9:DD7F/C5.G#$>012EE":F%+9&=B3"='!E:4'>"D%2D#@GBB<?/7?',/H*1@D57)F=&,G:1>:(;;C6A
@r3295
TAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGG
+
>C4""+8@,A-3/,5A%$E'6&&$E(;?%E43)5.9;<9$4('<2G&,-9-'3&!.3H"AC0")C$2E@#><556<./+#&1*):@=C(8-<636(&@5+3'?H90&@A)"--8#CF&6)HG88(?:EC:/3C-%ED7@D1!5>A7=3'B@%>;8HH,%049
@r3296
ACCCGACCATTGTGTATGAACGCNCGAGAAAACATGGGCTGTTCCGGGT
+
B-0DF<>157-7?4>@<;;,$3@8#;%521#=/,6/7>FC8!GE-%4,F
@r3297
TAGNCTCTGAGAGAGNCAACCCCCNGGCCGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAANTAAGTGAATTTACAATATCGTCCTGTTCGG
+
%'%%**'($*"%*#(&%(#)"%'&%$!&$+&*!('$)%#(*##()$!'#+)'+("$(%#"""!#"!('#!!#&$'&*'""#(+")!'+"%"&($&%$('*+!(!)*("!%'!%&$
@r3298
CCCANCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGG
+
(<#+649>8)E*D0(@-!660%7G@?5*4B'$!18?8$=8?"@
@r3299
NTANTNCTNATTTNNNNCNNNNATANCNNCGNNNAGNTNNNNGNCGANGNNA
+
"#!#"!$!"!$!$"""$$#!$""##"#!"#$!#!#$!#$!!!$!!#$$$!##
@r3300
TGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCT
+
@7'D*6$%+B6'1G$4;%95@$EHC@3%,.D07G060H(#5#*
@r3301
NAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAA
+
)96E:%=$:C'-$6"D<$G%2'8B8(<->564/@79CD#D$4>-G;3'&AH#:
@r3302
GAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGC
+
!%'+)%*&*+!###**(")*!!')+&##'(!$*"%*#)""+)('"$+*)*!*!##*)##*$'#*((%&#
@r3303
GCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCGGGTCAGCATCGCCGCCANATTCTGTGNAATACCATCAAAGGTCTGCGTGG
+
5@3G7)$BAH;=<1<=>2!FD#E.$-/2'!G':-;,$2$:)D&6<8GC?%:D:@7H<2(@7F82"-F/#-BF?/(D$?5*G<"CB)5(?H
@r3304
TTACCANCCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTG
+
(=:4=,;'">+2?&$<#-.#,9802)F03'A:)E/*%H7(B?>191"1G*8/$;C>9A9&(H3#G%3$191;<.<1!$D8=E&BD?/B,9
@r3305
GCGTTTGATGACGATGTTGACTTTCAGGAGCGCATGGCAGAACACATCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCT
+
1":((*2=G6:;,$"19C7-!%0),)*?C00G9&)EH$@1%%8;80A%@;:2A?+-:2EH5$:3))0,E;.H&6!/=63/H=/"CG22#**8#CEF<@>$/'2%F))ED,9592DD%@5-G)8"G#DCA&+99868-
@r3306
GGTGTNGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAANACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTNACTTCCGGCGTGAATGTTNCTGAATCCCCGATCATCTCTCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCNTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCANCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTAT
+
%1AF1)*0=@-&@)9=%,4%2>5$%#@&+4D==B+G!A7:!&,+.!-@2D"8$B$/E7F)1,7:.0*/?1<=8(-*<*8'<62C5;<=1F0B-&:;7499.G*$31D"A)2D9.1,71B0*+=26:07DD$:D(-@A))+C=6A0G?8F&$B1(E#,*)0@F1"%-7;:85-D(?=:77%$31+,"#ACEA'C?::1.2CE$0+64G$&96*=<66'28#>>@1$8@?2.,:FCG'*A6"9+/!:-4=.!50*D(&0;E;?))6H:-.=+)$(>+%&)0'?>H:=+=C*5+<A8G>.G/BE:8E)F.GB-(*%,D92E?C3E#BG%8C12*B%;F@1*/(E:9/9H?@$'#4)G.GH
@r3307
NAAAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCAC
+
#%-1&;D%&H8)9B*$1(-F,,8+4*?2F"H)>(EE!1G9'?9<+H"E9*=EH>E'3=!8/2&!9$3>@7:*
@r3308
ACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGNGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTANATGAGACT
+
8GF%:.*D+1G308'BA86A:3+#B.%G7<=0*C+::;1:496!E!8!B7(FB>A-/5./0D?1/C=G"60F9":8.3GHA.&+*3C7)-..A$6!0,D0D):+<1A#--/4F7!)F"=G$("H%7B+;E:A1%F1$'27B7>20%:)%5782;8$!35!:;F,-9;27;#A$C*#7A>0&4@C>..9G>*(+EA>:.+%57C=A!1?FBC99@5HG&E.G=/7*7+D%#
@r3309
CAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGTGGACAAAATGCCGCAGCCTGTTAAC
+
&F0*2#66=DE=+(D:B8D8*%@H4/3'9#B"*!)81@%0+)%9#D,8G-1;=E&%20B#2/=;94+./AH.@17@@9%7/%%/8'>C&9<8B-$$G9H13$88;H=6G)E-60>7&#!2CD:*?4#7)#G%4#&#AF,H<<68)'B='@5'C8B:<H,!D12,3":G':;#&.&GC(A%F>B750E*F8#;8;#$AE?.4')=<=)72+,G3<+FF>%;;6/(2E!#'-8#$4:GCB!9,).DD1H4E6<#A542.$0900.@=*/*>02;.B%+/*,?F94GEB<?.H&F,;!
@r3310
GACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGA
+
."2-E*A-@.-09,=#8(@E99/!2&*>+F;-',7BEE5"58@B3GDF@?8"&+41)-HAH1E&)A08:7<
@r3311
AGTTAAGGANTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTT
+
557!:4"%H>23-G0,B9E3#-,!+1,G9)B;77G$&H/355&)12-8*$&-?""D9?>EGE3<4G<752A4BF4E4.5H<0,#(4/9+6(44*H9+)<8?67?915(2'):#+@&+"#4,D(*EH04A+4,*/
@r3312
TGGAAGAAGAATTTGAATCGAAGAGCATCCNCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGC
+
(B9)+D@8>0!8256H%-(+E9'#1/<@$0)1?08.-4B/HH*029B6#F3(21D7DHA=+"%0?46A2@,#&E!!"AC53#!4)3!@4=A2CB83=3-*,D48,,D%633=;*=;$,F*>E#31$E/:>,@C-0A"2#7=6'=',D><:F@G:/,9*<>BDD&,,D54:"2,D:$"*6*57'851:%4DH#F#AFH$-@1:!#=?>@9:35%/=>&F%>D6"*:='F/69<3*0/C2G0.3;/64A7A**&3;?!59+8?51:08D/F'+49
@r3313
CGTATGATAGGTTGAAATCAANAGAAATCACATTTCAGCAATACAGGGAAAATCTTACTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTT
+
F*2A+=0C//%1)&<68E:EC!+85FG;H4<7?@6&6$38B,(D)3,8B+<""GBAEC;7=2E$"(,&7+@0#8D?'A33>C7-"-;/08.E<!672@>:#=%4/9#C6&,9..C2726.9
@r3314
AATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAATCCAA
+
"&-/E<7+%$#%1BGEAH@DA;E,B$"8.$CH$GH:)>+++!(!A4<")>CAF9;)G0>1(A.:+<?!@-3>+G>'#3=8
@r3315
NGGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCNAGAGCTTTTACTGCTTGGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAG
+
"(+#%""&($")($$$*&'$))!'(+'##*"+&)'+"&#(!!&(!++&!)"$$%"*!!*#"(*++')!*!""+#(&"*$&&")!(!%+)!!$)"#$"'#(+%+)%"'&&(+(%!()+"'$'&!(!&%#'#"$(%+&+(""$%"'"!)'+)(!!#$')#!))*(+!
@r3316
TGCAGCCCTGTTGCCCAACGTTACCCGTGGCAANGCCCGCGC
+
+?//97<H@GA8+E9.4E:?H#0*BA:A;7G>='8(%C*F$(
@r3317
AAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGAT
+
(B2(+.731/!,";!5B#06,+E;#@C:F"3#(*@!CA.<F2!+B?!?(+79:3+'589@*(3(%..!(D=&
@r3318
TAGTGAGTTGTATCTATTTATTTTTCAATAAATACANTTGGTTATGTGTTTTGGGGGCGATCGTGAGGCANAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTAGGAAAACAA
+
>/+D,5'/0DD+6398!.0:,6.,$<8!419D6?3<HC%E'A7/)60>*/C$H'='<C@:A'-&6F.,+F@%*+496$ED-,A9"%9+"#1%#8'?)(D=@:."2>/689-G,@(&D:*;>B#&')2&D8?5!6+/
@r3319
ACAGAAACCCAGCAAACATTCGTAANTGGATTGCTCGGTTTTATTACTTTAGGCANTTATACTCCGCT
+
'D!0!=+29BD;>D>,5/<A6:D92C9"*!D;)7(8%(624E5';<>G9%;)D$>-7%B).?)968C)
@r3320
CTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGNCAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTNAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCATTCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATT
+
%&+%)%&"$!&()%!+&$$'*'(&$())')#)'"+'%(&(##(**+$*%&*%))*#%(%++#&$+"$)%%#$#$&%*#($%*'+(*&""!(+'%+'%#&("('*!##%$(+&++(+(&')*"$%+"'*())(+"')')))$("#*(&+%$+'#%'"!+*')(&!'+*"*)++*%)#(&%#'##$'+'"#$"()$*'%')"""$("""&#$&"+&#'+#+#%$#)+*($*+!+(+&%!&*$#%('!!+'
@r3321
GCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAANGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCTCCGGGCTGTGG
+
"**B3@HE:<1!*0=763B!66B$"+DH(F#3.50&D/3-'F,::,,//)!.A>96+6-,6.<8<*6'3B5#&$#/@+G8'62;0%G)@45>A)!@B1C+$G53/@A&B.H50;
@r3322
CCGTCGAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAA
+
)*!)(&++)((%)''$$'#!+')&+'"!&'&)!'++"'%)!$&'*"*&!
@r3323
AAGAATTTAACCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGATTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACC
+
,<4B&!?566*#;EHE1(950EEF)<>416$6#.-,;E>++BB$B9:5FD6#%A5,8")&B'#$<?"/.D0G?-:17($G;6*@;'85&=+@D>>))?#4*7)%&<B$)!9=8'CG>#+.$85,B&;;;4C:>-.'!'=E
@r3324
GCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCCTAGCCAC
+
2GD,G,F*>B=##.#6$A1D(B)&$8GF818D60!F33#=48:$,=!><+)?$)7#2A.C3.+8C=2-&&+H4#&@/*:$,"6=A>;6A9:?EC@:
@r3325
GAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTNAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGA
+
G%44,H!,:"=79#7;24,2/.;?8&!+<B/>$/3)3;6=@0F<%?%G9>.)246*/9CE%=9%?&/H431*4)&/D/.H!2DDA)466<
@r3326
TGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTNAGGCTTGCATAATG
+
GD<.4-"%15!(-@'7FH@'%B.HB(/&8$"?<2%4%:/9A#C3-@06!/,(D(B89E3$,@0B*B3?G35.:C*7#=%G%?<H?$&<?4:)HHG+D%HA"=',0/E/>8(?941H.(?(@=6?CCH'EG=8
@r3327
CCGGATATCCTGCATCAGTTCACCACCTGNTCAAACTCTGCGCTGAACTNAACACGCAGCATACTGACCCGCG
+
5;=A9?.BA0D@:;@6*8%F/'-EB*4F":B.9=91/6#%!D#!E)8".@#"$8<9!H4*E+7&9!&0EA7FD
@r3328
ACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGAGTATTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCT
+
A-BBB8"(2%!/!*+/78(=),&5EF/)0/;$D.&(.>F9*#H(2/.76DE<2C4F$B-"<8(%$"*D@G>%C6=*E;,3/A%*65<72;E9;C:#3$C!6.+)@CB%.,B?C"$,3F82E!5$"!86D'F=#-4663@F$42A@B6+!-=@@7!
@r3329
CGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGNAGCAACTGGAAATCATTCAAC
+
'0::'>E1E!63?E(3"&)*)>?3.20G<6@/0E733H;9*145+980<?"4<9(F6(E3@)025&4$-CC?A0!1:3'(F#/9D51FE
@r3330
CCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGC
+
FG/++F230E#2/2(;:*7@#%;8(##87!9CH2#H?./".H?#-H1>8C7F.C1E"C?C2)-!</A;C(32G1;
@r3331
CAATGGACAGAATCACCGATTCGCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCC
+
$+$+)%)!'"'%'&()"#(%!$#$+"&+$$#*"%)"&'+&%+++)!%(+$%(+)!%(%*(+')#("%('++#'("+(&!!+)*$((('&%&(!&*&()%'!&&(%($'+%&(('''%$"(&++&"')+'%(+%"$!!&!#$*')#('+$("+%!''$*"#+)"())$))*#$'%&*)&
@r3332
CCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGA
+
0!$0F#2GDF?$$,$5;9)"2G2))>E=)>F045/!<1-")650#/,'=H
@r3333
AACCACANATTCAAGTGGACGATGATAAANTCACTAAATTGTTTTATGAC
+
51:&?817:$">>?BH!"H+-(?.$:*15<-.@86%H,84&E17'-:+(,
@r3334
ACAATGGNTTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCA
+
91+#3/7)*@!AD$45-9$7$..HH&H)"<&1'>>:5)(%@!7/99G1H$87:+2=C10G'2/.:+@94E%+#!@G1%*F(4"
@r3335
CATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACNGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGNGCTGTCGCGAATCNCAGGTNAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACNCGAAAACCGACATGTTGATTTCCTGAAGCGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGANGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACNGTCGGGTTAACAGGCTGCGGCATTTTG
+
?(3.D#4D.;<E.%'*H:CG-:+-C?BHH37-6#9-%:7@*D$2"?&C4!A4D4:C:A38CE'&.="H.@'/9>009=C?:*45B8C>;>F)G=>HF:F&D!"$&/>58E.B<-5?,=*=2A2,GC:>G/()0C2"2,6D)?C<%:G,>2;40A"CBH((?=5BC'<1<5#3+>B(>H*6D*+F6;%%B$9D;<:=9F-D"=,2F56-61B%F27D2C,>A23G:512C6$;5/3B/<=8&4?F12(42644>DG,7&GE(*D.46-/,E,7!+<F8!'C+/;B%*<9@E=7;!+8>%G=.7A)4
@r3336
CGACCATCTATGACTGTACGNCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGATGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGT
+
B$DB93E1C(EG<9A+"',F!$!>1;8*CCH(D11DFG/$'*36*E/2A@)9?.<=*7<G(:"(/@)#G$.%BCE/5(6A/H,;2F8-6!D?4G24"G9)%#6#!.&@)=*3-4#B1,*2142BDH9B"C:-6<@'#;1:EG;.G*#@137D*3<#!7BG!$E>G2
@r3337
AATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTAC
+
'G-3:.>)191#C'!>F95E#6,CH>DG6E?C8:**0:?A$;"6!&E4F@A?#5%/!=EAFB/'9>#$H((
@r3338
CTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGANCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCT
+
3BC-946:=/6(F85*G?@1*9GD9,63<0@H>5.6>3.<E<92D"H%73=7"G&*E8'31DC)73<?25+.6--&514,1'<*G'3"-?7!C
@r3339
ATATTNCGCNTGACNCAGAACANTACCCGTNATCGAATCTTTTAGCTCGTACCNT
+
(%))$!()'((##*!%$*))'%&&*")*'!%&+!"(***+%$)*'(*#%"#+"!*
@r3340
ACTTGGCTTCATTGCACCGTTTGAAAGGTAACTTTGTAATCTCGCNAAGNTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCC
+
B4B<2:0ED)5>GE(('E2(0EB)$)7'-G<+'0CG)<H?&?3AH764+EH0&56>AF"5-,!052?/%3/(E.+?#$#>D)>.F#70
@r3341
CGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCNGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTNTGGCCATCGATGGTCTGAAAGAANTTCAGGANGCGGTGATGCTGATAGAAGCCGGACTGAGTACCT
+
:<=*,DF#;B=!/29!&5@6))E-<D09==H"10GH9&2&"09((-!E9<CB@B.>AD"G=%F'#*+?!7#FH=4*,C!#H'%"<#.F-%8@A<<77H!/2+>D?2F/,-(H<C!,5!6(-6$(1F5!9'9&C7&H+9!A+.27<0,D..=-7BF)<
@r3342
NCCNNNAACTACTANTAAAAATGNNGNNNTNACNGAGCGCNTNCATTGNNNCGATCCNNNNNNNGGCNGCANANGNNNANNNNCNTGTNNNNGNNCNNTTTGGNACTTGTCGCCNTNNCNGANNGNNNCCNNTAATNNATNCGGNGNNNANGTT
+
#"$!$$#$"$$#"$!"$$"$#$!$!"##!#$"$"#!!$"$!"!"###"!"#!"!#$$$"#$!#$$##!!####$!#!!""#""##$$#$"#!"$!""!$"$"!!#"!##$#"!""!$!"#$#!"#"!!#$!$$"#""#""!"#"$$#"$#!$!#
@r3343
TCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCG
+
C,+=4D0FB$.-80!)/:%$!-:2<6?@61;F./=7@1'E*!/<+B>1*&/$C0$4+E-92@G3&E(B,%FG">8&;3G:&H&<-)27"%/'H/<)<0H?'%/3:**,?-G1>%97792CH6E"%7:H'+-A1#/:BB'(C**(D43,-9!+9()>"
@r3344
CATGTTCTCTTTCAGGCGGCGGGTNTGGTCATCAAACCCTTTCGTTGCGGCCTCNTTCGCCGCCTGNAA
+
3@D&*5$%/>GFD.H58AF,28$DBD"#$;(%5/%713"+<D?8(C/-5HF&7"F)(0FFH)+2'4;-E
@r3345
CCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCTGAATTTCTGTCATCATGGA
+
:*"<<:,?D6.4<"(!!-"@811()G!.:/06@$'!0.$/,05<1<%?::"4";0CF2-$*!F3;=,2F+E.+@,57;*(5&1,#9
@r3346
GTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAG
+
C>'0'0=8?'!)HC>(B67>&#)9;2.#9B<,EF9)8"H2-7.F(E%E?DG>5H9&:>'()
@r3347
CCTGCTGATGATCAACTGGCTTTCCAAACTCGTATACGTCAAA
+
#'9<"4*%%H(#+&<(HFE?4#:.*+AD</>4!)3>*#0$=5?
@r3348
TAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACNGGCGCAACAGTAACCTGCATAAATCAGGCCGCGGCTAAAGTGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGNTTGCTACCAGGGAAGAACGGGAA
+
E;6@0'H4=C"">H4E<"G>C1.@H6;65$<9.".D%31300!2?D!2)=C24.?!)(5-,1(#!B811E/3*G/!5$64'HA!'"066)/>)FF(7<=8F5+6?E+A=B0)3/&A(!#G@'<*,1(6;B",8*2>%)HE.77B0G;2C:'D9@BEE2#?
@r3349
GAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGA
+
56?3A18GG#?3@"(2#!(3HG<<AA:4CH=2HB&$70-B=.-,!<;
@r3350
ANGCGCTCTCGGAAATGTTAAAATTGGTTTTGTAGGNCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACNCCCTGAAATGTTTTTTTCCTTAGGNGAAAGCATTGACTACTATGTNAATCTCAGCNAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAC
+
'!#()'+%"#+")#)%*&!$"#''"+!&+((!'!!'!%$)!!$+#')$%'%$%#%$'*"$'&*!+!!+("$*'"!)&$)*%)+#$+&'"%+$+$&+&($%"$&*'(!+&%'("$%+!(#&+(&%!**$+%($($#!(&')*(!$"!**+**+!#+%'!'&%%%'$'*##%##%%(&%)*!#'*"+)$&)%
@r3351
GGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTC
+
C>5G?+#</>8;4<(;,+?C,$AC%G942B8G)6#&&;$@#4:01>7+&*:B:G,?/$EF79/3AF2
@r3352
CAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAG
+
74C?G7AD5B8)#"@2B%8;.++DE0:C4/42?748A)H"F%@;3%)<<78)2)G>F9&@;5);5%B/"2"B!+,7:3#8"=4$H8.H*C48<$0$F-$6D3.";B=
@r3353
AACAGCTCCANCNTANCTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGNGGGTGGCAGGAGGT
+
#*&"))''"%$*!'&!+$&$%#'!)$"&((+#!#$$(!+#)$''#*$'!(!*"$#*'')(()"+%%$&()!#')+#!)#*)#+&!%&&)*$!!)$+'!'&&##))&%'!$
@r3354
NATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGGTTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTNGCGAAATCACATCGTCACCCATTGGGT
+
#<.GA3.4@8#AC"?:,"B6.B.1-9!(2D'&D@((C+300D8.&6,4;';=8=?>2"1'5;F>&EEB>=206@/8G.=,7:;!:G7B+5EBF&8&87%,?9+.=%40,B+<5/"*7FA%C>>?<B,506%FE+30C5<"8:9$@((.-@6B;EC(&'.
@r3355
TNGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATNTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACC
+
*!,7:)A)6-*"2A3:*&,*F:)06BF:3/9&D>F1;)E#G-!)694,"B7=9?=AHE3#,.<.!.3(A4E3-(B*>=DF??!E;D<E;=H<><E93:C))(":B7B$4#$B&&*5#")66$
@r3356
GAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTANTTTATTTTTC
+
4+:;A./!9D#?2'5,A%<+&#;-*95/7%=8)D$+BA42D6">8?".,('E7#)H46>
@r3357
AACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGNAAGCGCAAAACC
+
:>&,ED@75"+?C;%04"=7/A**$,:H99;/7,%@D9A<!8B;.47B/G'7/H8
@r3358
ATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTG
+
F5"()$;*)B+5&8!'"?F?-H,.;2CCHA<+"&,2G5%&A'A#F@EA6&0?B((--92#'8<994<
@r3359
CCTTACATACATCTGTNGGTTGTATTTCCCTCCAGAATGCCAGC
+
-E7)#>$2"#<E?/5E"&@6D',3-E47+%7D57/G10:9:C#>
@r3360
GGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCATCGGGGATTGTTCACCGTGGTGAGATTGTCTTCACGAAGGAGGCAACCAGNTTGGCGTGGGGAATCTTTACCGGCGG
+
-F4F>CA;-:(D%(FAG>;9;0*@H4'.!'?H:$=$D)E)=F)),(430<111BA7;$'*9C".=-:+"$BF5H.+H=DF4A;A2"%A+!>7>*E!'4*HF6C*8:,8$1:8H>5@(2A=B>:HF&#HC!A"<'5,6(/B@$0.<82?F8G5F@.@FB0G?HH8H$2B@5$E+C6&
@r3361
ACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAG
+
&<>6C9;C%D4./#"36,'(*5'=6")>G35B"76*+DF8?57CA$*!1=%04E,3&%$.C2
@r3362
CTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCG
+
B3:*=9B2)(G=2F<D5+*E>"FG'1D.(&1&//C@4"A8+""6868D=E52157B&F:1;4/DGH4-,%GFD!-"4(@4&)<*57?0%0:+9:D")CC1
@r3363
CTCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACCNCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTAGGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGT
+
=<#/?@,</H0-#'2%"3*6?CC!D471E8<*A3=F;:'"EC(6+$E%=0?;5.!'0(F'G8'F;#215E8&8#@<.HA6?"7!(E1HC&B,!(7*461+.:H7)E)(#7C761?>5E='CF(8$+5.13+C#*+9,=;3%>#=21*=16*#3!8@&G%-#)$9F4&/%#,8=3CC2G+!.H)<8*;&"F669'++&>B@%A60-$"+'H%$A7)$E,@H25;6;,6>()E3
@r3364
TTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGGCGTGC
+
=-03-;85E3=/F/?+(A21)B4-5;:B5*3C#("<B1A*16&9)H%?$:-&73/1@.7?/%')/**";=.B#&$+4HD/218<H@-#2/<;8B
@r3365
NNCNNTNAGTCCGCATCCTGAATGCAGCCATAGGTGAGCAGACCGCGCGCCTGAGTGTTCCCCAGCACNATCGTGT
+
!)!#"%&"#*%#&%))*+%!&)'&#$&("))))#'&#&#*)'((+*'+$%$!"#("%*&%(#$!'"$#(*$''##%
@r3366
GCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCG
+
%H>76/*0"(G7@D+?+>.%GD72B/%';3+9/'"5/?"(?@<D'.7!4$&<H:H23$3B=&:6
@r3367
AAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTNCCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGAAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAG
+
;$G#@?;3,&G!:05::=,C#>').+C=B@@"*3+B*5(AF8<7D$9H7,,#;+3:94'E6D569-+78'#?8F5B#H>1D,HD$4&!C)!+'E8<+G*E$8!0(?7&%7F-=>(.6C#H'E$>&7(48EC#<=<'0@7ED"=G*:978@9$E=9$C=(2338882G@""+FHA<0"B-.3=&C0D2.6HG0!(-8#A)*=>A%2-CAG)6,H66&?06&)$7>#=*"<$AC8AC36C>*F&'&D33'7)4+$+59'*5,F';%-"&58!'=5&DDH%=D1?,&&;,($,5@
@r3368
CAGATTCTTATGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAA
+
H,9>.,E6;=0*/F<E@;,4C'/>:CGCFC6=>F9'B292(8*($D8#35D
@r3369
CGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTNTCGTTTCATCGG
+
4:8<?55<%>"#F.91D%5;$:E/?(4H>!.>$H(9:<&.A@46H&:<C#-
@r3370
TACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACT
+
H"6)&;@,(C%.@2?6/$;8"3@A2!2134!?H<G?#BC6!@2)!76D-?G%"%GB@>%$%)5>
@r3371
GCATGCATACCTTTCCGCCNTAACTGTAGTGAATGTCTGTTATGAGCGANGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTA
+
?1CB;@H<H''62G4.H/GH:8':*%/8$0)-&C79B5-<C3CH;#6"H37:41%9;""1>61/;6A")4,8/4D5*(82!,E&C--#5&4<;:+D!8+3+!H5%.;CE;'C
@r3372
CATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAG
+
*-B;6688%(?<$0F?2@>*AD&$*)F8>9%<036?4C-G1CD=-.:<($,**G-E0-HB2'#=HD8-58,1C?"H-B+&C6,'C%9BF!#!(1
@r3373
NGGTAANTCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACTACCGGA
+
*9(/>!1&GCE=3:C6B*2*44>+'-)<05<F;?(+3H71B5&176(F+89(<H3:*28$'2<?%!';'<9?<5AD9;31<)>E=?4!!9?9EC2?-'G'<)GD/C0%
@r3374
TGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTANCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGNGAGAAT
+
13'6=D:*9%1=<"14**.@B6F84?)#.D!H+8H"%-4/4>1.':=6=71E@*C>#."D7&+2@&928-36%?)6(B38<HC#;6;6:0B%6@#DA,A0*?.1#$"
@r3375
ACAGCAAGTTTTGGGTAGGCTGATTTGTCAAGCGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCC
+
#?%5%!A56=.59*(5=>H=+@,2%C#5+?7F=?D*(G:.5-#033#B7A$A+.:>'/87%<344HH72:&>1/66,AD:2/9>6+(<''32;7H"9@?E5;H;>*481%/
@r3376
ATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTANGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTACCGACTGATGCGCGGCTATCCCAC
+
8D*@):918A(D2<,B>AB5)7"(%#(<>D!":>B"4H375E6+F<!D$"7G-/$=#8!6"E,98#:0(8@)4?6!,+7,*"@C.4$'GH+-E=/!>F!4=@!BD(74=*#E'@&A06$='2A311"8<<E#)4*5##2&C%%*"4F+!85."06)>0@(=!%<G*B='?&C#@1"'.:5F+&-C#2<
@r3377
NNCGANANTTNACATTCCGTNANNAAANCTTGGCTTGNCGCCTGNGGNTNCG
+
#%&'*&&$)#!**#'))&(#'&#%)""#"$(''%$'%)!('%)''%())$'*
@r3378
AGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGNCCTGNCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGG
+
>1-9F+9>7!/6G5'*CDD"D40>$-'4;%G"*&H&@8F(@7?)&GEE/'9H$!%-A,B*1%51#*,?3#>6%5#H%&DG<)+=,**HEF>C
@r3379
AANNGNTTNNNANTAATNNANNNGNNGTGTGCTNCNNNNTGNCTCTANGNGNAAANAGCNTCNACNNGANANCGNNNNNTNGNGN
+
#"$!"$$$"$!#"!#$$"$#!!#$""!#"#!""!#!#!"$""#$#!#"#"$!"!#$$##!!#"#"!!"#"$!!"#$##$$!!!$"
@r3380
NNCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGG
+
"%%$+"&)!)*''&)*)#%#"($"*(%&"&*+!+)'$*)!%+*'&*!&!+")%!($
@r3381
NNTCAGCCCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGA
+
$$1G7'A@/4*67$C76/C+B&9"<GG7)(.5(%=89?FF8')?288B9B98<=,A"82?H+
@r3382
CGNTTTNNTTGCTGCCACCTTCTGCTCTGCGGCTTTCTGTT
+
*$!()!!!!*')&+)&*$&"&+((%&'+%!&&!#(#&()+!
@r3383
GTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGT
+
<-&G0>:#>:-@-77:,#=335D-C#8689(/,--:-FG&?;!0-"HF1A"G7.5?'%+/+0A;:E*9:6C7!F;),273;0($/9!+%!A!:3F1,9D4EBF?5)+F<(+<GD#9B>*7%5!
@r3384
AGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGA
+
.6G2.G@7@3;&1G2!GA7"C1><64;DF=C)*#B002+#/2-4B/5*@CC8;$H;4+!/5-=G1&
@r3385
TTACCTGGCTNATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCT
+
=5863ACDBEHBB/=>?H9;8D.'&D63F4#A-@!@86EH:E246<G+(A1#%B6/>E%*%B*-16*2?F,9:FA1
@r3386
NGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCTTCT
+
$%<2-2;)=*#9+8774<(7%'6C1;C+HF9$-<4(CB3@F9GCC"FF!=-B"3-.A>+=0G=33>787#36?5F7*@-1=<5D0:*!7#"D/17=(=9%<HFEC=,B:8%.5=;)H/;.$#.F'"6?76=00,0/66A?>47";/
@r3387
ATTACGTCATGGTCGATTTCAATTTCTATTGATNCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTNCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGANCTTGCTCCGTGTATTCACTCGTTGGAA
+
=<25-=*D!/?E59H6$-;!C<&A+>8!7/>*G"=>"AEB49'5B!22"#0A,#F=0-("0.(>9/F?-:#;&4.9(=H*-C8"B51:$"E>G/6HG@94*94=4DH<E4*B<@$A,/"H=)-5)+=#.CH:36;0D43&+;<G%#+?*4<D2+/3&/B#(1F1<@FGA3"65H(E*D5>$?:)G>-%'#/*5C),1@6&!*7E
@r3388
CATTCAGGAACGCAACCGCAGCTTAGANCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTT
+
9B/-.@E@;7F<0&6%*0%#!D907'GD<GD>('1=<G2,G$CF510#03/5";"2(%3$!6$16619=@+:+,?3@A5,-H,4&-;'.H'F:84E)D)E$..3G7"-$C$,?."=*:3F.4;
@r3389
GAGAGTGCNTNGNNTAANNANANCGCAATNCTTGNAACTGAGAAGACAGCGGAAGCTGTGGACGTTGATAAGTCGCAGATNAGCAGGTGGAANAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGC
+
(&*'((&%*#%)%$%)&""'#*"&&(#)("'&+!"*"+#+&!(#'%+)*)+"!("%))&)%(%#"!&+"$+)&'+#))!*$&+*(%'$(+!')#)!&&)%!##%+*#)*('*$)(&"("#%++"&&!%#*!*"*#$**")&%*''**'"*)*"%$##)$"'%(#++*"!&!"$'&
@r3390
GCNGCGACGNNGANCNGCNGNACCNTATTCCTGAACAACTGGGCAAACGAGAGAGGTACACCGACAAATGGCAGCGA
+
&)#()&"$)%#&&#(%#$#(!%(%#*'&''+++$!)"#)$*""!""%!$&####*'!))**#&$('+%#$'%$+%'(
@r3391
NNCGAGNNGANGNNANNNNANNATANCCCGGCCNATNNTNATTNCNCTNNNNTACNGTGNNNAAGAANNCNNCGGCNAANANNNANNNCGNGNGNGTANNNNTGNGGNATACNNCAGCGCANNNNNNNTNNGNAGGNGNANNNCGNNNTCNNNNGTNCNGGNNCTNNCCNANCNANGNGGTNGAGCCNCANGCATCAACGNN
+
"#"$#$"#$$##!!$"$#$""!$#$"!#!$!$"##$!!"$$$!$#!$!"!!""$#!"#"!#$!$$!$!""!$$$$$!$$"$#!!#$!"#"!$$##"!$!!"!"$#!##!!#$!""!$!#"#!#!"""$!"!$"#$!###"$"$$#!"!$"!#$!!!$#$""$$!!"$!"!#$$$!##$""$####"!$"#"$#!#!$!"$##
@r3392
CGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTT
+
4E/9HG>'$2.-2F=)5.!.33&D)1E1"5)'8F$4.#;.,<5&3.(.$92#:D3<+"=D.F#6$);3H";-)/3:#?B
@r3393
ATACCTTGGGGCCGNTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGNT
+
$+($#"+((*+!*"#%)'!+!$'"%)'&"$+&$)&&(**!+$)!*!+&#"*$#&#"$#!)"*%"
@r3394
GGATGACTGGTGGCGNAACGGCCAGAATCTCNATCTGGATAATCTGGA
+
B5'8#9*#9@)!=*G<G-C4)0D)3E8@A!8&%=G<:"0A.83*;B(#
@r3395
GANGCTGCAGTGTACATCGGTCAGGATGCCCTTGATGCCGNACTGGNTGA
+
0;A:B!)/$CG#3?.>3%D&"*6<'4D?1C2$?0'6#$DH(:+8(%3,5E
@r3396
GACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCG
+
/:#)$0%#?G6)0A=4#E(.%4)<5?%B/A330<3F83#&6B,4@$H;592='#-!#?/!:DG#
@r3397
AANNATNGCTGNCGNTNTNAGCGCTCANACNGNAGNNTCNCGGCGNGCCATTANCNGGCATCNCCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCGGCACGAACGCCAGCGTCTGCCCGTTCNATACCGGCA
+
&$#!$*#)("*$)!#&"%$#()(**%*!))")&#%#"$$$#*"&&%*(')"!'(%'')(%'"'+"'$)*$$+"#*%#""+#%&%((("&%'$!!"$#*$"'$(!+'*()')'#(%""'''#"+#+)&$((!&%))')"%"%!(('!'
@r3398
TTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCG
+
G<>D7==#?(790%7*<HB7G+,'<6"3%8D!79A)71"G2G/?E4>)
@r3399
NAACGAACCAATCGAGTCAGNACCGATGTAGCCGATGAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGANAATGGCGNACATCGTTGCGTCGATTACTGTTTTTGNAAACGCACCGCCATT
+
%'!($+""'+(#"&+!*(+)+&)%)'"*))$%*++))"&+)#!+!#"()&##)(!*+)+%*#!)'!'*!"'$')%!*(&)$++#*$$%$&+#**#%$($'$+$&+(&%!)("$%)(&#)%)#%("%%!"'!'(!!!$#%)(+$*(!'#"$*"("$#!%$"')
@r3400
AACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGT
+
=H9@H(F*'+AGC<5""<3B(;93,5349+3)4/!;5G$F)7G&=
@r3401
AATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTNACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGANCACCGAT
+
*B;G&"+.AE/6;&H5A*-B)!&,AE9(5"71;A2F-C93H=-1*3=;@/601*>;".B&F3E;/3@@/G.&;?!$/;95$6"64;B:;:17+&>*6F?,B20/=(:?A-.B,97!=C9<H:6>1.:=?#FE.+3>+=6AD/4(H-#.-%&2HB(,%6-E;9$::.;,A3GD8%DE($+)"+$!6+*A+9G+6@3-
@r3402
TAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACCCGCCGACT
+
H$87,&*01!/71*:H"BF@:%?1E.;1-G)9;A*)CFD-G%CB:D$<9*B!CB)-/9F7:B9B@093(F<.A$$=D.6C5@&""7;>2&%!%(?>-H&C!5
@r3403
TTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGC
+
GC(#187G!F>C!',5)B;%E/A7?3CH,182D,668?1<(,9D1H>F529>
@r3404
AAAACAGCCGCATTGTGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGC
+
F6&EF9=55C-:4)7&;,A2B(3?3=9)@8B?3523:2-&!DD8<29"0&&D5'-BG3&@*>:,A#6+(%(;B/:@?9)A6G-*#3DD9.$-B&D'3)B)$63G@0!<+)+'E>+:-2.3E+-C<698;)0:4H$1
@r3405
CTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAAGATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGC
+
00"0*0.:GBG=2;"7F.$3#&?(/:5=@>1-5%=E33C>*39BB).<936!<1,H:C,*C@!F->>'A>H->4;#!:C$G57>E>**(9;&5+="";8A#<GE!&-A@*%7+<;C-FG+0
@r3406
TTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTNAAAAAAACAAAAACCAGATTATAG
+
>A2?>=B#A:7+&A-AB+?/8#(*%A5.1"$B865A.:/%0$#"!;%4;'6B)@;1'$E/-0:!,/7@B$.G86=/-4F54=0$2$2.9G#*54#<BD3G5$)-;4#G
@r3407
GTAAAGTACAANGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGA
+
DCC><*C0:7.2.?H&11!2.F!6+&-+DH,;(AB5,H&">;$$8&AA#G5,.%<9H""&129C:8)#D
@r3408
CCAGACAGCCGGTACACCNCGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGA
+
(897C@6-CF(@:90;(,*:6B=.!,A/&"*%7E3D6=((8'46>"*+>')A%4(3@38C!1.2.37;*=+B2@H#7B3/>&1?H74-#&8%(D-5H'.<'
@r3409
CGTCAGCCTTTCCCGCGGCTCCTGACTGTTCGCGCCCAGAATNAAATCCATCGCTGACTGCGTA
+
!68@+).2%5?!=.00.D$21,>F&7F(&G)H$?&F)-:&9+4<1A/6CH+0?+D',2#G%(1F
@r3410
AATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCNACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGACAAA
+
3F0>*!F5!8!(+;&-H8:-?*"&/7(9;&&FH7>/4,,")*ECA%G!"F33!:D+F<<.H<>3;;/6</4"?27A'.-%(#:D!A=)4.>=8!)=%;<E/G10$/2#"%3)&5-30.'0'E1:,/>9FH=</%E6<ADD5280.>>4@01$C1#$+#)E:+H+5$HE5>04HB<9F'73B*EH=;)$&E2)@FFH;C$/
@r3411
NTGAGTTTGCTGCGGTTGCAGAAATTANCGTCACCGCCAGTTAATC
+
$270)HF:(D&A*5?GF2H42#4()B3-<:(36#,B+F9A,;26'G
@r3412
NNGGCNCANNANGAATGCGATCGGCAGCGACTACATCCGTGAGGCGAATGTGGTGAAGTNTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCGTAAGCAGCGCAACACCCTTATT
+
%$%&!&))$")')*%%)&+)"#)!&'#')&""$)!('$&%##!"'$%"+&'+)"#())("#)#&$'*!$!*%!#(+*&#$!$#'&(!!+(%'*"#)'))#'$""%+(***"$%)&&#'!&#!"(%#!"&+$('##&&*+
@r3413
GGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTNG
+
+#'"'#&#&("(!%$)')'&&##!"$(#+*%*)!$(&$'")"&)+
@r3414
GCATGTTTGGACCAAATAANAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGACGAATCCTCTGACCAGCCAGAAAACGA
+
-*5!;:!:!9#@5;;&2E!438"%7,%F%9-(6G/>,<?@?)611(,,B7#50A>DB'/>:931@98F)3$:A3.:*D5665.1233()'(4#>H=)B;$?D89E>*"D?3$/;'6"3(#%(G!'%C8&7@11?6*$#E)69445%D7-H!>A%*6@&EB-2F#GA/"==!2EGB%;54?38-1)#<&7(<C@C#)43-8BH/H4242
@r3415
AGAACTGTAGCTGGCGAACGCGGCAATTACTNNCATGCAGATGTGTCAGCGTG
+
+*$3$"&/D0G(3;?CE%A40$:7?"='.>B5&,:?23@;.B69H'!%<2,;?
@r3416
CCACTCACTCCANCCGGACTAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGC
+
20B0D$$(47<#<%.7:8(-CD8&G*H%91$',%FE:,A%:9366H">G>;!G"D6'=>HD"--F63<918,)>=*>
@r3417
CGACCAGCGGCAANATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCA
+
$017B:*4'%20=DB&1+=1+%!*B9!/%?G+,,+<'@:55;C+>#D56)H
@r3418
NNNNCTANNGNNNNANNNTNTNCCNGGNGNNNNCNNATGATNGNNNNNNCTANTTTTAGNGNNGNTTNNNCACANNTCTNTCNN
+
##"!#"$!$"$#$###!!!$""$#!$"#$""$$$$!!##$#"$#!!!!"!#"!!"#"$!"#""#"$"$""$#$!"$"!#$""!"
@r3419
CCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCC
+
+3CG?D#55B&)7*&)B'*/>.'68-+#:'#,%?*44(3<.$7;<*&-?3G:49
@r3420
CCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACNTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGA
+
9495G(0+&4A"9A!=;5<(-&BFH"H1<(A/-B54$!/'E0+867HE'93..20$7A369=?>-'2.);,8%>@!>5A*A)'6A:6131C=&,B0@55:11+"5H4-(D0H#06#!E&<5.;FH<4>CA"=D1/?+3(1"$2A<D&B&2-77*BB'!F6?1H<EHFDBF$%,D07786B4*#)%=D72?((C<!#5E3+F#;A1DH0G#A1D/<'7E@+!95+A.:#4G@><C-)012?F("71CA25?4,(>+79#H@+D"#C0.=<<+DC+$%/A.!D.2;AAG<A8#G".?'+)=:>
@r3421
CCGATGCGTTACAAATATCCATGAACATAAAAGATANTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAA
+
%1F#C8-8#B";E*-40>"$/*:29(9@(%F<*H,D5$7B4!,?F8=,'ED0>',=G:E1@9'<DDG>G0GHC*:+HG3A&#!"/-C/)F,/">@
@r3422
CTNCAGGCGGATNACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCNGCGGGCGAGTNGTCAGGAAGA
+
ABE8E$DCG$*.@AH%((!CF=CG>C9-6?"/;!;*3<D,>7('!*<!<*F8,)GA/!8C$,(#<AD)?1:;(:"1;<@#"/(54"5)H,>90-"##+:'!.1%."53!E'G%1
@r3423
ACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGC
+
3&99@C1"*13E<&D,,$@3B".$'36.".,3#&'4;56,.756"'<6?-=1>B*60F=FC.D?'=90>!-95+&>.)
@r3424
TTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGNTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACANCTTCCTGTC
+
53$70(,=3,(<"/)),*%3H5+@&5'+$#D.'D.07=G&C@A9$G>/;2=.;>#>6G4=#)&&1;+42DB@4,)9!/13B%*'<E=A,GD+G.C!A18$B/,5F-+
@r3425
ATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTTCGGTGAGGTTATCC
+
6@9!@9!H5>0*.H3$?4D%/'<9-7*D?,:%3>@)%5(-2;,E;-&G0?<<#3@?+5G&-H;E#B3E+#(0,-A41E&'4$:F;.(<,5.2$C4)#/5B$E)*21EC*--H.ED:<53H/E;&3;'*:19;AE?6!7G>E6*A>$/'@"B/@2$H=G#%C$A#$HH'4:,)118&$:!++'(=='':;'1-:-4&0-,(#C%$E4(3798F,358.*,B<->6&4!F#0B:(A2'H8E;;B4,F,:@&F*'D<
@r3426
CGATACTTCTTCCAGNCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCNGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAA
+
+$"7@4-7?=&HD=1.9B26+>"%1E!;@:3DA)2H!D1?>D@G<**8$<0-/&!!38!C67&;;):!G&/785?1E)!3(,<>#;9!-1<&.)2B#&>85>+:E:%7:$2&.1*4&#BD'&'DCCFG!.=:<C*;5!'=G#2"+;26#"6E$<)8C7!8627=4/#!4@0G:F=A4C8;,/,!=BA,('?F;39**F@;54'B:F%7!+:<%:0
@r3427
NNNGAGNNNANCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCG
+
$#))(($#"(!%&+)!"#"$%&#+%$')+*+&%)"$+&($*$%*+#''+'*!&!%'!*%&*$&!!)+%"#
@r3428
AGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGACACGGGTATTGNCGGTATATGGAGTTAAAAGACGACCATCT
+
:>2C4?HHC694&=@:*#<2)'(A1GA-G$*H3-+3;3$!$DB=-2=A,%3%<8C7#."G'#,3>,4022(?(#0&H:)7E%A?038','9#B?,?=
@r3429
TAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCNAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTNCGCGTTACCCGCAGCGTTAACGGTGA
+
&(+"&$#'%#+$!')*#*&!+&*"&$+$!(*#'$"!+"%"+)'+!'$*'!($#(!*+*&("&%"&**'')"'#"&+'(&#$!%&*($&)%$#$!$*""%%+$'#))(%#""&%&!#+""*
@r3430
CNNACGNNNNNAGGCTCTNCGNNTNGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGNAGACAGCGGAAGCTGTGGGCGTTGATAAGTNGCAGATCAGCAGCTGGAAGAGGGACTGGATTCCAAAGTCCTCAANGCTGCTTGCTGTTCTTGAATNGGGGGTNGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCGACCTAGCGTTCTGA
+
(##%&&"(!&"()('("##"#!%!&#"&+#$&("!!"'%+(%!""%#"#%&'*&&%$#(+*+$&%++(#(%$"*'&#+'$&%%"!""%)()'#)%'*+('%()'&+#*#((+)*$"++*'')"!&&%+!"+&*$('"))!(&%'$#%)))$&++*%"$+)*)!#*'*&%*#'$')$!'#!$!!$#$)#!'("$+'''$($"$)()(("$%(*(+*#"&'+!#"#$('&"%*$%&"*$(#*)(*"*)")'"%$"+!+*&
@r3431
NTNATCNGGGNTCCNCTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAAC
+
"*%&(#!(#&(("(&*+')!(&**'+")%"!+&#%()"*")+)&***(&&'%*()")!!+$*'"%)#)("(%&+
@r3432
TGGNGTNCNGCNTGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGC
+
(#!""&(%#%%"+'&$&&%")*(&#%)$+$"&"#%*""$$"'&$"!+!'!
@r3433
CAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGG
+
+*+$"+)#'+$*)$(%()&'&(%'*("#!!#%&(&%%%%)**$+*%*')*("%+#(%
@r3434
GGCAGGTGAAGGACTCCTTCGGCGGGCTGATCCCCATGTTCAGGGGGC
+
1(FH1),!$,4/8/+D.(4?635+$.,&/$9''>4!;)!*1E9C0;2'
@r3435
CCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACA
+
?GG8GFG=B.D4(,6E:941:A<6!A)<//%,2H5,9A1+%CH<F7/;E1HE'-((75
@r3436
ATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACANATTGATAAGCAATGCATTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGATATAA
+
?E?C@3<9?@%5(75BFE8$%H,=%(/8#=3''@3"*,833F7=928/'(2;,2:?$266,(7):5+87!/>30BD2>(%,*E'!0)0F@63G%H:6%172A,%,8'8E">$
@r3437
GAANGGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATCGCTAACAGGTATCGTTTGGAGTCAGGGAAGCAC
+
*($&#+#++'*$*#&!!")(')#&!"(+%*!(&*$$%')(*%$&%)&&+*(&#&!!%)+)'&(*#!+"%!&!&#!"%!!"(#$"#'!#!#+
@r3438
CATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGG
+
54;G'").0E$9/E#;9*$&'E&2E7!'3"8#$C7974F%55E2?9
@r3439
ACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAA
+
/4>D9@;&+)>,@4H8:F<G!?:7>??4+":HE(F,>>B.8/#)90=23(=GA/=>26-G(1.A#?,E22;@C$679'2BA:CC;@*-3)6$,AF@
@r3440
NTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCNCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGTGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGC
+
%&)+!!*+#(&(#)!&+)!'(%+$'+'&(#!#($#(")"))%$()&*)+*&'#!!!%!$(*!+)+)(%"*!&#(%!&$*#%"%(+&")&*&*%$+#+!')#"'!(("#++!$!"&&!!#(*&$'(+!#"()$(&"!(!"#+&#'&#++%"##$+$&#!"!#%$+*)(*&)$%&$%!"("+$'&#*'#$!+&*)'#(+%#!)&!#%'$%#)&(&"!!((('#%%)+##!'*#!&$""$"!)&"$$(+!"+'))!'*'**$#%%'"(#')*"")*++((&#("!"&*+%("(&")$%'")#!%$("*&$%('"$))!$"")$!!**(*('%**)&'$'!!"$%*")$!$+%#'#&'%'!"%*"+*'("(%""(+')(!+%!+)!&#
@r3441
GGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAAC
+
/+@:38HH"!<'5D)!=A*@&G/HE#87.44+160.8&:#.-115+?C)
@r3442
CGCGAAGCGAAGGNCAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTC
+
.$8:>B612?D(340>+2?GD09(<?G(,5AG4D@D*:E3>?G,/,2??E@1@9%/E'6/2"(4:F!..581+&#+1313=G*$946A:FH<GE'G431)=2FFC%;$#B4#%!D+H,@)C049,EC2(835*E=?7E>/;:;:D6G!/$$"6HCB-/1;1),F?&#.<'E
@r3443
TGATAATTCATTACTATTTACTGAGAGCATTGAGAACACTACACAAATCTTTCNACGCTAAATCATAACGT
+
8,7-6??/6E/D85F!A.(7@401C>)5C-A"'&<2H57%GDHE,)GD:/+6BC,*0?C*4(!:9,G"#(+
@r3444
GGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTT
+
"CC!"8!&4-!2F44$1.58@?(";3=FC'/"93*:;>C$*76%,;2),%?+H2H'12+4<85.(<'=8&"
@r3445
NTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTC
+
"&*8-G7-9D3*/1#<=%C=&21*)+2"-AG@0F:#/4?4)
@r3446
CCCNATGNTGNTNTTNNNACCGNNAGCANGTCNNGGACAGCAGAAGAACTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAAC
+
*%'&&)&$%&#"#&*!#!)''(!#$(%)&*"$*!)%+$(!*%*""!"$#'')"(&+)%)&#$'(&+#$)#&$!&*"++!)'))%$$#$#''%((+&+"(!&(#"$+&$'
@r3447
ATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGGGTTTATTACAAATGAAAGTATGTTAAACATTGGTAT
+
'>C$769EG??..0E56/G06/:(,?(0#BH.>9"G<76.1=)#0:-1&,+=9:3E?H88C2$H;7#G*%:)$@B-GB6&*&!+C/!,1=C-+<,>A7*==&;'D5($>605.%E<@+$
@r3448
AAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAAAAGACGTCTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCA
+
,3-#37%A7,7D!/D(@8!.E?D:'9"*1*#G767>(0D;D76'"?.;E05&A**:H83$',A,G/+#4@5(51>EE@<5(+04<6+@1!!D:=31E1$E=@6?
@r3449
NCACCCTGNCCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACG
+
!&("&"&'!+&*()(*'$)%)#(!#!"'&**+%(+("!!&+$%*%()+*$+"$'
@r3450
ACTTCCGAGTCACAGGGGAATGGAATGGCGAGCCATACAACAGAGTT
+
=E#3"@43"-H?2+6DG#9+4EG6?9>'"","5H#GE76;&A7E0$(
@r3451
ACGCCGTTCACGGTGATGGTCATNCCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCT
+
;5!4!!H&!-":!9!#D8)?8<:)GD;A,;+6<<2))DGG056,<"H%HC46>C?"C#G,B(5(28:C5)$,B96>'
@r3452
CCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATT
+
(@<$?"E5(@9.%/#8135F7G&0A61D*G-CF8F6+H64:8
@r3453
GAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGC
+
G31&F4.7+4>6H659#F8&6C."B%F7;0(;+D"-70BB3;$?51714,AE2&#57.%'0-=DD8G1@E+0B./6$!(@&/F<'B%A;*;#1HH?/$(C"=,%<-)!8.,!#.05
@r3454
ATTNCGCCCTCATCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATNGCCGCCGCTGGTAA
+
"*)%+!'%("'$(!)%+$$*%!!'$!(*"&"'%&&!*(#!&#!+%#((*$)#*+))$)##'#(#!$$()"("$(+++')($"'+*+"!"&$!")'&&($)$)#((')*)%+('%+$)"&'&*'!*"!+!!)#'#*($!#"+&#"'$&+!'*"()&*'+#()%
@r3455
CAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATG
+
.,?7/+GG.'69.(5)/!7$-1=)*?=@F*:>025+&)#BDA23F@GA8*%1">1#/8C<)A!"#1B?C/>A$G8GE'?7$<%.$,+'))9%/76@CB
@r3456
NGTGCCGCCGACCANACTCTGCATATCTTCCGCCATCCCGG
+
"++$%)#$'"#!"&"(!('#'#$!!+&*!%$&&("++"&#&
@r3457
GCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAAC
+
63131B0GEAAG9G/@G(HA!A.B',8F@'!57&%59:5H%F"DG%&H-D#-6%<;C3,3'>-G/(C=B.38<1A'HHA@A#0
@r3458
CGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGT
+
C-0$(AE71C#:#*/2$'+)E0&4F')(=H4:(E3EG'@F5H>:2)"D+A%0%:(>2.$=$=C?88--!#9B:0'1/09<<)A)DH5-6>H,E-+#7:-CA5<9"./$!$/%!E#>3+!=(=$.40=#5H,D%/F<A,##9'A%/16(
@r3459
ATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGT
+
/:C,9F2(9,3&A#(2@GA1@4=H5"B:/528"3:'.8A94<64,0-"%)+3)1=)-/,@.8-HB/'",,2&<,2;9:CD:::6?*1#;8FHH<(H%B#B2D!%"#D4535;8-&7!D2,F3*0D$%;)H;45*G/@-=2)"&C#.,503
@r3460
ACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGG
+
%(>!#D+<E(F40B6C/<";63F$:A=/4-E@,0/G3A3F
@r3461
GGCGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTANTTTTAATACATAATGAATGATAATAATAATATTAAAA
+
*!H972#***?#$G/'#%0D4<8&D$5<)"<4H2686>E(1F23&C:<=#BCD+:1"/->"7$;>)@@19="F6*<!71<-G+C?6;><8,(=203,(*%D$H9
@r3462
GAGCCGGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAG
+
*%,D0>*!#8+9=/>!)=:*$6(59;#:,@*&"9/,$:;G)D'C4
@r3463
GTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGACGTGTGCTGGCGGTGAACAGCCAGACCCGNACGCTGACGCTCGACCGTGAAATCACGCTCCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTNAGTCCCCCCAACGTCACCGACGGCGTGAAGGCAAAAGTGAGCCGNGTTCCTGACGGTGTTGCTGAATACAGCGTATNGGAGC
+
+)"&%&!!)")$)!"'&"#$$#'"+$*"*%(*+'"!&"!*$('%*##$#&#*($)$%!+)*'(**"'$%)!($'(!!)!+*'$#&$$"&*%%(*!*$*"#!*#*&*%&&%**$($*$)%("%%%"'**&!$$&+###)'"!&'%+%')$)"+'!(')++"+#%!'#'"!+"!)$$%!+#(*+)#(##(&'%)"!('$&"$'#&#)*&)!)&(%"*"(!'(+&$(*+'+%)+#!+$+%&)+&'##"'"+++%!)))&&$&)%("&*("(+
@r3464
CTTAATCTCTTGACCGGATGACGAAAACCAGNGAATGCCNTTACGGGTCCAGA
+
&''#""%"+!%#!#)&&!"$#%*#*)$+*(%*+%*%!)$""'+*&%'*+"$"$
@r3465
ACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTAT
+
D25)@?=?92C/A%(>130?7(<!,'BF17B5-;3F0<C37/=A@9%#H$&&/1,07-09ECE85(/>GH7@D1E1(4;C86++?5(-059+6,!@164-&=AG:9C#
@r3466
GGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATT
+
'3%4;<(=2D3$'9/938;:F:0/:@"8%-"51G3($06.0)3!5.+71C1$+@9E>/&4*AH4)0FE-9''EF>).3"9>>52.30%E%6(F*-"8(F4G-E(/(%2:5'
@r3467
GNAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAANCAATGCGTGGTGTGCAACCAGCACAAAANCGGAAATCTCGTNC
+
&!''/%2<9?*?B$%$59?>/$(;#":<).3GDD!(747,7#>,&6E/!8D=>:34FH$7>!<C*)0H)8-@&>G!?+EE<.#E,H!D35A,7BC+.H9'"F//.4>14;8/:!2.&-B0+7:.@.9C=8<:!<?'2!%)"%@F59-;9&))'A95H+A?<1;-5>H?#
@r3468
AATTATATTATTGTCATATTGTATCATGCTAAANGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACAGCGT
+
@FE#20%/'8*707A75"86B:F6A%20::.),@D1C.09(*7=>4A%?7B5$!/@6''965+#1.$ED8A(A(E,4?%;(F4!.8)':8>?6B''A1="#.=H><%0E,@?&69&3H@BB#C0".8%0:$=G:9
@r3469
NNGATCTGCAGCATCCTGAAGCGGCCCAATATGCTCACTGGCTACCTGCANCAGGCT
+
("++!))%%$"'$'&"%&!"&)*((")+#%)+''$#+!%!'!#*&+)##($''+!"#
@r3470
TGAGCACTGTCTTCCTGANGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTNTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGNGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTT
+
3253684F"D.>*88,E4;?/2=D33(CB!+154@C&(C:5G@CC1G67C<@.179!;<;2C#>3?A8&%&*.A$>@?/G&2AEG%B$!F:C;,"0G9"*32,,;&-D249;>>@-56DF+))B/0B&#!;8D%B*B4:/(<9C#4#-'&1E'#C
@r3471
GAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCG
+
'%!%"+*&$)%!$)"()(")%$%)*&'!*$%&#++))#%$!!%''#)'&"*+*&(%%$&$$"*
@r3472
NCTCGATGNTAAGCANNTCGGNACNGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCA
+
(*("'*(&%"&(%$(!"#"$*")&(+"%#$)*"'+*#!%$""(!#'"$!$&)($&#$*#")')'#+%*!%!())!!'$*('$&)'+!""!'%((!&($!*!+'+!%*()&(((%')++#&+&$"!
@r3473
AACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAA
+
B*;B?=2FF7("D/H,",""<H=C"/6H0+2E,:$(.=;:%G:&43<D8#50!"86%!9D>+3(4C,B&$)-G91*9425*2)?69@$1-06)177B$#6*1=5"E>%%#3?").0G<-=$8G>(*99?(4*/0%9""2
@r3474
GNACNTTCGTTAANCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGNCACGCCGA
+
(**""#+*+)!%)!))&!&#(''#*)+*)&#'*##*(%%&!(#"*#)%#+('"%!(&"&*$#
@r3475
NATGAATNCCNGNNNCNCGNCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCANGGTGCCGGGAAGAAGCATCCATTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTCCCGGAAGCGAGGC
+
!&$))%()*&")"(!&#$)!!($$+$%)+(&)'&+!)$**#()'+&+%%+!*'+%("*&+&$)%%)'$%!!%"#($'$*)($##&'#!!#&***&(#$"##"#!(#+##"&+")!%%'(($!$*'$*!%"#++!#))+$$$%&+$!****&!!*'
@r3476
TAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAA
+
#H=D::5CB;'61&3/$B4/F-10?'FC86"56FH:-<>"BB3B".=6;%25,=E/C+:9(9?*!7/;6>E5F!'/<-(A0DF*%:1
@r3477
CTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGG
+
#?%$'.1%A)C9>;9D-+7#C=@G</>&?+@63@$3>:5?7H?(:$G(($B?7A3>:.'C,28B64)G0A:H5.@15?.5
@r3478
CGTTAGTCTCCTACGGCAGGCTTCAAAGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGNGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTG
+
51,&0*G<*2-+"77G-.09<C31A;=<9)8!,!&DD%4#F1>GC).<&B<8@0,@4,5;!3B;(,-#70;#?CB;13A7)$5/-;$:7!#F!("9-9-*1$H%"C4>17"&7CH4BGF+'>2@-E%5F@'*"$C6C;G,>$G69/<B$C)&,4!',--<#9";,?%@?9>-H2B4:
@r3479
TTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTT
+
6#5D,$,<!!&3*(!("$88&<:$C</)<,;0+G)<98.8)A7,/'+GC
@r3480
CGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTGAAC
+
A+.C17:G8:;!GC'>&0E12!A9(*5"4:!&H#C?'"'$+@%"+$
@r3481
AGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTT
+
D&+8?H>D>5/HB>@5&C<6=."21*6F4(:8F>@D?"3%E:H0
@r3482
GCGCCGCGTNAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGNCTTGTGCAAGNT
+
."A/%3&+,'G6<%0,'A:G/"--91D)+E$AC,8D164;A;H4>%@/(;6H3<@@&5=-B4@2C4=$,=-G:-18;=4@:@4"@;C!=/;D52&&!A,"H&A$3BG+":
@r3483
GGGCACNGCNTCATNCATAAAATTCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCNTAAACTCCACCCTTCCTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATNCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAANGCACGGGCGTAATCTGCCAGTGTNTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGC
+
"&'*&"!#!*($&&#+)%!+)&'+%$))$("&!#+%#!''(*)!+&(#&(()*&'#)%"#*"$#$%*(%)%$&'*&*+#&('#+)#)#&%"&''!#$)'"(&%'+!()#*)&"*+)&*#&(#!)"&&''"'!''+"(('#(*!!&(&$(!$*!$')!')&$)#''(!"*#%$*"#)$)%()+&!$"#&*$((&+%"%"$$"&##$!)"%&+)%#%"$*'+'%+)$$&"*$$+$!(**!&!+&!*)!$'#++")#'%$#+$*)')$*!(%"')#('#(&+*""#'++#"%+'$$#!##(#%'(%%&(''#%%&!%$$"*"*&'#(#
@r3484
CAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGNTATTTACTGGACTGAATTAGTTGCCNGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAGCTAGANAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGNTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGNTCGCGGC
+
E?8,%:A/1:$H&//<=*%)F(*.:>E(7!*EFH00#2>A795C!'HE%40-/#.+!F0A100%4&/)%;?EB;E-;$F$:<>G#//53.G0E>D'"3#5/4.(<1;GA#0<F)"):?8B8EC-0DC=)H951<7@!/>91,)@FE4?<$027$H&..>@3#1/DE9H,?EGA2*F:A6)0H.@/$G7?#+9+)H.6E(64*-$4A,<!0&$&=A4HC&*>-)%6EH:!D;C/-/>6%61GB1GB4-'-)<"D,H"880'3$5!(.G;$)?@2"872(9,7>;,G&(D/6=F7;37"3>=4.D.:66F(442@"&$3==2C)5*30?$7$CD'62F2(43E2)(A0*D-8"".-F7,C*@*)E&75&'<D/'$/=0$H3%:C$00)1,-;56#/')414;CD+7",7++8:E1,"3?/;(>@F$A.G,<3>5>%
@r3485
AACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTA
+
G?2AC3HA;0E:E97C4H1%E@E=6'-&@=')*223.'C%;E@"7)+3&3*C#-A7>B=?#<$@
@r3486
NGNTNANANNGCNNNCCGNTCGCCAGAATCGCTGATTATGTCTGTGT
+
%*$$!"!'!$&*)#&$#'!#+"+)&+!*&*))*%"+!%$##%%''*'
@r3487
AATTGNGCGTGAGATGGGGCGACCCGACTCGCGTGCCATGCTTG
+
&!#"&!%$++')($&#$%$'!!)!"!!))#")(*!$#('#!!($
@r3488
GGCGCAGCCGGACGTNAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGA
+
95;!5<-)1";?"/:$1(C79"(2GD(@56C$"E'%(F=;<@;1H*!@-D8,;5?!$5GD$+$B8B0H
@r3489
GTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCA
+
F9$'-18@E).*2@4#H8!4/-)7=@6!7057/GGC?6-)F*>&GE)C+0(?H*.;DD10,/?8-C&;B=H8#!C83""+6(?'10>9342*$"&5D9GAC;
@r3490
ATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGT
+
4-((>D8-./F=(0==-&$684'8?660)#'%%7'39F,F2F@7(B*:A,';0;45D66
@r3491
CAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCTCNCCAAATATTTCGCATGACTCAGAACAAGAGCCG
+
1C'(?H-*9"A7E-D:+.DH!=2=42%!H5G#<,B<#""&008)#D)C7@?(8(2>D2+:2>3,6)CF
@r3492
GNGANTNNNCCNGNNCNNGCTCNNTNNCTANCCNNTNAGTNCCANGCCNCNGTGNNNTAGNAANCNCNNNGNNN
+
#"$"!$"$!###!#!"""!!!$$!!!"#"$#""!"$"$!#"#$$"!""#""$!""$$##!#"$#$!!"#!""#"
@r3493
TTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTG
+
G&15(%)D-/*$@+6"511C?(+E;!&;";"17*2"9(9H99)E;9+!"B..>$17.)0EDA*-,&>1HF=!57%"F"<>'H8.*!.FA4*()#@/5!%':D)A2-&4CF.H8?3;F2F067?"3@>:
@r3494
CGTGGCCACGNCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTA
+
=H1$-E(*>9%<G,<"/#0FB/G',>6<.DFA*G6@@4#."<0+H:4,/H#0.9=880GH)D/.3;/G;!D82%.+@"B@HH*.874<2B=(&GF
@r3495
CCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCG
+
9.F)0G>/<47ACF"-)>).E<!B="@'BF"%2!?375CHA+</;8E-/5DD2,01E%2:-G-'**97'@!)>H.'@<=23<+)2.HF#E/>9.2!:EDB;B@./'9*@)+-0F%@G0A!B.A$?$(!.!>6&$2FD7E>A4:;37(*DFF90A2:?/$6%.G".-F>&&"H9&&4!2$1)'E@)-DH%%*2G
@r3496
ATCGGGTGTTGATGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGNCCTNCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCAG
+
:0$0?)./*(:43>*E<7$271>,:/=1EE9=!<C.+5H)D'7>A)(3:GH?-&8&)D%;&>ED:>>2;%7=!H7A!2&0/!#@&DB!7$?(&?&
@r3497
CGCCAGATATGAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCANAACCT
+
DA&+A%/3(2D9*%;<>D+9;+$1($04@>73FC&A"3:39*>!"*18G@&3-">)$$=!<4BFA=5BE@+A&3G,5B
@r3498
AGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTG
+
>8'D.&780><<>DA5F*6%H%/3$79E"B$@B:75D9=5G!7,9'!H;;5;0'>&0158;H&2
@r3499
AAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAA
+
HC$!D<6?+07$;@&*+-G>(>6)<59CD?8/--<FD6*G#HG6?(>D@A2HD#
@r3500
GTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGC
+
C0(A3H+1?+63HB1:4#7.0B3C'2+*0@+F(2+!1;+.%5B?B/'1/;*#
@r3501
NCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGA
+
"F&>1-@6G++0B=B3+7%;2>9/%;F0;D,=A,D,4C#5;%'B!3-@.;0@#>
@r3502
CACGGAACACATCGAGTTCGGGAAGCGGATTTTNTAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCNTCATCATCGAGATAGCTGTNGTCATAGGACTGAGCGGTCA
+
D-)<!H?<(>"2H7?F:89!A*51G?)#!<'&<,-A<&400'?.?*6(-,%A7G;"05C<)-BE/!<7><*>23<!1/,/BF'B07F+E>%9>E!"E!G25*50B103)$3;0%$;@("G6$)!#(*;@<07F=:,93:$3/6*?$49HF"1*?F$/(%F*CG<=7H7D>>2)E=%G,$E9$9!G(-=&*(,=H?;5$#"E53!0.;C'
@r3503
TTGCCGAATGGTTACTACGATTGGTTAGGTTGGGTCTGGAAGGATTTGCT
+
&$&"#$)+%)%+%+"%)&($#+(&+$)#+!%'''"')$$+$)*&$*'+$+
@r3504
NTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAA
+
"*H2F?+!AD=,:8(46(>-4?2?F4"7&-FG/)F73-/A-9#8*34@=@:;!B6!(9G@6*C2=*==3!&@@3"CC<B82F:F)?-"B3<0!.9*A?3:G%C0@%C
@r3505
CATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTNCGTGTCCTCCANGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTNTCACTGGCATCCTTCCACTCCTTCGAAAACTCCTCCAGTCTGC
+
??<B/+$C!B.">$=50D+9G?3,C>)!3H+@E(9>H,HG-#8>%/.82A>?+E-5::@?&A)551:;2"B1#%%9(G;,(!9:13,C3:(4!+1$*'!?A7&"5>."?H=65(*$59)7@*C<<FG)1--HB8;G?)03@-AFH"?"EB"1!%G;'F!=C(32'=AG;*4B0;5-,G%!#*6'D-;<5/;D(>7&0D1D77*B#/2F,;/*$)72<.=!#$';2@(9E:%/)A<<6
@r3506
CGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCANA
+
24-9AG@2A/0+<2%0%G!48#E15<0)<H25+30#>#B!:
@r3507
CTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCC
+
=(.7>F6A;?,A%#6)B0'?/$D:-+<+%-,H#6'%#.&!(=@+8C3-+D-%-!<&77%7C(<&%9)C?D1)H47=*-A@;GC1%G5F1EFDB?>)@@'0+&-,*/"<
@r3508
ATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCT
+
B:%89/4+D8C(%1*1-B2DC3-@6.$%?7"B,>5C/'$!E>>2C=&?.;'?02-#=D@A.#1<<F84'?7E>"@C=$2&#D>-5)-5D/4&=.>7C'/6!').AC=A9(F)/4:G#
@r3509
GCGTCCGGACAGGGGCAGAAATCTGCCGGAGATACCAGCTTCGCGCTGGCGTGGAT
+
+F.7@7FH+-A.4G:*278>./G:D')=GG>$309H0!D4E'1@,>-;/;C@D)%4
@r3510
TAGGCTGATTTGTCAAACGCCNGCCCCTGCANCAGGACATAGCCAGACGGAACGATATCTGATGGCCNCGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCNCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAG
+
5<52G$/6EE79.4F+-9H1!'B/-3*?%"*%65"&/&B=());>2/F%"D'.5;.F%-;4.=37-?=;#63E?G)'=!EEG6:>>6:9.+#77)H1&)%!;!@GG=1<4H4';B=(9759B$$!+!81;.9663),,*(>-4.(1:H/#84
@r3511
NCTTGTCGGTTACCCCCTNCGGCTGGAAGGCCACGGTCAGCGTGGTNCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTAACGNTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTAAAG
+
!?55=@A!A'%.$!?5H#*=9.B6)B/EE$H(:<)9)544C4H?!(=H@%)2+1./CG?80>?D-C@E&:$A-)1G,7F.E/0*8298);)H;17$0FF"5G<%.#,<*)81<6;716,D(;+B,+9"3&"()1G19E'.10-)&)>>.*"*%B;8!(A/04F<-1-;"@77&G45>"?4/C5,925H"2=7>G22AGADG!759FHABH*B$='>=H)-/0,29*>9@.&?#'F?;(-B<?;-B!7F+='E?
@r3512
GCGNAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTNATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGAGTCG
+
#$'$'++$)'&&)()"(''))'*&++!)&"'"+$*&)"*'%*##'&!**('&$*(+)")%'+*"(%!*$')""&)&%!)*++)'%)*"+$'%*!%+(%!#("$#(+'++"#%$%!*)*'*)$#"""*%!##$'%$+*$("%+++'(
@r3513
ACCACNTTGCCCGTGGGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAANAATCCGCAGGCCAGAAGCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGT
+
(%@6G6)54!>%).@B/?H!9C3.?8%?#.B-%A9C:A%>%=>5+#:;/$4#H1?=H:GC"=5"%$25GCB-@G$@:H0'$>"..7-?14/-?0'@G%(-6/<-@28@4&84@;5,6F8G59!G6;'9=?)1.%)/,1=*G307D
@r3514
CGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGAGCGGCTGAAGACCAGCTTCGCTGGAACTGGATGGCAGGC
+
4(3(,G/?4#=-*BC(43B3"=$0"&*41/9+!))./$"2F5@$/H%8,!4&06<AB5++6/CH5*H0?%)!@%<8H70,+>12>,&7B&D3=21':+!EG<C?)"!);DB&'867:(2C@:&9?*6@0,3D6#3(;%D6!B4?"?,9+#@HC3!&:80=C9'G::*<26DF@,FBD2'2C9F'8"C504/7-F322/8%=AD0D8'&0BGB
@r3515
CATGNAATGGAACATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCA
+
%"+*)'!!$#)#!&*$%$(#**)#%"($(!%%&&&%$$"'+#!!*+("$$('$'
@r3516
TGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTT
+
)'+(%"'&($'&+'#(%%($+$'%'%$%%)$(#((()%*(#!"$+&!"!)#*$+&*!#(*'#(+$'))&&#)!!+*)$+#'
@r3517
CACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCG
+
EB9,:-',GE;<,=)3C(:D;B9GG0&+G,)>54<-36>06/6)@$28
@r3518
ATCGAGNTAGNTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGNCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTNTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTC
+
>>8)@'';;19F&DD'-;D16?#(7.!D3@E2>,1>58''-)07:A?##7&E)3'.G+E?+#A.2G-.,G;C=E-%7ADH!<>:70-8/</3:G5!'1?E5??F@8(9CC56&GC)"BA:#@66;2D?@5=%DB>6;C,//0:;#,#EA,>BF"@5/-$)F;'&41GDA7&+B:=:'6=)?9+=?<)F*"9.2#@6A(/ED"&$#7%!'"A4G5/+%86("5)E'H!7=DF>9G?6>$=#:%56F!#'%5C:C)+2!)&4+H;-:B!%=D!G4E@3.H6:<<AD9,H:0H>2,G>%*H0,>,=A:2H&57).<>4+2$#%
@r3519
NTCATCGCNGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGT
+
"'*%')&&#*#+%(+'(+#&*(+!%(!#)##&$)(*$%#%"&+
@r3520
CTCATCGTTGGGGTCGGTTATAAANTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTNTTTNGTGGGGTGAATATGGCAGTAA
+
>>>#)*0=/BHDB//G8E'802EHF.,328)1G#8@+G)H2!=/8:H:&$A2<)04G!2$5"+4!"("21#)@+@#$6+A95,4D"A52*1)#.D&@30$:39G
@r3521
CCATACTGNCTCCAGCCAGAACTGATCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGAC
+
-(.>F&+(,C-0@!:GF3+EA@8G2G3F=319D<3G>C,&08).G9!F#7EGA+7A*G8.A+-3,91('C2D*B-<-E%+3:7>E1&=?:F>H)8<D9<?4G:@B,-G77-+:6GD&%#!F8C#1E?3"-&E-78!)"!D&>;3#"<=:'HA,"!.<BB0,#CHHG;1
@r3522
TTTTTTTCNTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTG
+
3/6)H/5F?1.B!8',$#3<<=0$).7@A8(<':#9$71(:(<?1D*5)A86?&5
@r3523
TTCTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATNGAAATTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCC
+
E'<;!$;1!-:%2#H"CC)F"GA''HH2G#&6>.A$*#4+'138$)(B?>5"3:-D.E+#23E/#'1&1E*<>&+E&;8>"<3(*!;8D*59/)F.&AA0&1-*83*?:F5C&D2$-4EG(0D=6-::"F?.4A"$+-?-6'.D!B(A01$%151517A'$'@7#089'0D'(>@68.!=H5(3@;&;=@754
@r3524
GCGCTACNGCATGGGGAAACNTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTG
+
3@CC1F$7(..FC&DBH*?>"DG6'?)5-(EB-,B#='01&A+*%:D68EGHE$7)G3&"22C,@/-.$$E:,H2BD=;*%F.)?FD2B-&5;-$79'9)=
@r3525
TCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTNCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCNTCAAATCT
+
(%&+%$'+%)&!)+#(*+"+'&!+)!)#)))*&&&#$+)*'%#&#('!%%+&$*$')%"&#")+*+))'#%%$*++*&##(*)$##'%$&(#("("')&')%*++(#&#'$$$*!&$!!)*$+*!#$
@r3526
TCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCNCCTGNATCAGAC
+
=1?>#>E<9BCB@.2%HGH(892E8/HH66.#)+(4)="F(+&%1-C.AF@/E0;B@D1H7F(0C.+:2).+
@r3527
TCNCGNNNNNNCGNNAGANNGTGNGCNAANTGNGGTCNTCNGTANANNTNANNGNTNNNNGNTNNNTNANNTTCGNTNNNNGNTTGNNNNNACAGNTN
+
###!$"!!!!!$$#""$##$"$$""$$#$$"$"#$"!$##!###!!###$$!!#$!#!#"#!"!$$"###!$#$####""$#$""!"!!!"$#$##!#
@r3528
ANCTTTAGCTGTCTTGGTTTGCCCAAAGCGCANTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTA
+
#!60'3/>8@-1)6,H":B:)9/F$/E49EB@698&(@&84.6)08'0<H)5>4F%$<(D$$1"6!"):66*5CB)B:%?=DB8&>&*&/>GE0
@r3529
GCTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGT
+
%''')'+!+(+%+*#!*"!*&**$(#'(!'+(*##'%&")&$#+"((!!#!+*$)%!)*#
@r3530
AGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGAC
+
0%4+<)?"B;0$GC19.13A>='"A<61@0G(HE#G4A7@7H,6E<4H=C=@%&)>D62F2*,6A?2:;
@r3531
GATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTANCAGGGC
+
*D9$@'$5@.G)&&3$*A3<<5CE1->>A<2%-/6%+B'1=/"B,'."0+E1=7DH82?.+H1=
@r3532
GCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATANCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTTATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCCAAATACAAAACCAATTTCAGCCNGTGCCNCNTCCATTTTTTCGATG
+
.*/5)=G.B2"$20*'3>)9=7=C:#0'+F"G9D#.,H<1,751,2'6:>-0@)"+>%E@2,7>HAE=78!%$,54!F"@->A1H9>+*(C@@3+/,+CHA>.(8=/6D@:D$3<'*E2#:%#'#:"GD4+#4/+70@?9'*$G4=/9<6D;F$D9;!)7$><01B:2#A%,H#(#2-B*)
@r3533
AACGTCACCGTCGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTNACGGTGT
+
E.D1.9':!'&,2()@.?5<,3?!9*5'F,B;!06+0>#D52;FE>;9:1
@r3534
CTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCA
+
795FG)?.53>CF'%+9@:E@>(.7&:C0G2D!-H*%)CD'=$'9*=E<0:##?&=+ABH2@D5@2@C6.
@r3535
ACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCAC
+
'+!)#)!#)+((*"*$'!$''&($")$&%+&$*%$*"#*!"!+(%&+%%$+###)$
@r3536
ANNNANTTANCNNTATTCAGGNNNGANGTNATTNNCTTNNAAN
+
!""!!!$$$!""!#!$!$$#"#!"!$""$$!$$!!""!"#"""
@r3537
ATAAGCCTCAAGCAGCATTTTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTNTCCGGCAAAGTTACCTCTGC
+
D#*?7'&>53E4<&:?+A;9=)>",-819"6&-76:8E$%E)$/%?B+@G=.7$<)3.(*;-;B>H:(DG><F)'3<5;C)!;4!)7&B
@r3538
AACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGTAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTNGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAANCAGATTTGTNCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGA
+
>)6/%639.-66'+.9/?FC/A<!8(%,F!+1G:!+8E,B086=$B2?<B2'*,2>C,A-D8"++EB388(*52G>#>H!!0+/E*?(G'G(?D'+(15(.:97&,B8A+9"HE9.<4#?+25:72;2:(',,%,((5%@(>G1B"?#+9+'7<7@C#B)2-$G.9D.9-4;($?<@F</'9H#5+>F+C22128:%*25==F:93EE"C0!5,/252/6$,%3D5G/H:&AF#)*GCGE?43;8$BBC9$3#6:A:=E2>6D'0A%4
@r3539
CTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGTTGCAATATCGGTAC
+
A<5F'E88#!15?.7;>5#F4!(0@;(*4!&.'61(!$2()A&5C!DC5(0'"<F
@r3540
AGCGTGAAGCNGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCNGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTNTTGCCAGACGCGACCAGTCAACGTCTGAAAG
+
-E@3EDC<A0E#+F/>"&5.8!C5/C>&,D?;B;6".H%);2'2FD?1)(4*6C(+*5-&%/+"508DE?-0H&64"-(E!00/A2#;F&**,1DA@3:A,%1+9@9<#1A'*DAHA1/$5!A>4HA0+FA$(05A"-607BH;&A@.@9<19-&F41-:7
@r3541
CAACTCCGATTTAATGAACGCAATATTCACAAGCANTGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATC
+
/;51DD5?8C,60229!-*;)/40>%>H+6:+>;(&)=#/E8*1/,6=+G(!+:?B)>CGAG+1430.=9>(>'#1@3/.0'
@r3542
GANNCTNNNNNCTTNNTCNNNNNTCNGTCNCGCGNANCNCCTNCTCTGATNANCNCCGNTNCC
+
$#"#$#!!$!!"#"!#$#""!##"#"!$$$"!"##$###$"$!"""##$$!#"$"$!"#$"#!
@r3543
AAACTGCCCGGGTGATGGCAGAAATNGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAANCTATTCCAT
+
.D)66B3.1*.7F(3!3(EA(1#0?3F--$5/(G,:,"4)66+;7&@1$*4=D(#82,%-'B9,EE:D;=EG3'*
@r3544
ANCNNAGCCCCANTAAGGGGATTTGCTCTATTTAATTCGGAATAAGCTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTNT
+
'$)""'#+%##$()**%#%(#)%#*#*%)+")+*)"&+"'+)'"&$*&)$#(*$"$)'"*&!&#)"!#"('+#$*+%'+&+(+&+$'%&$(%")*((()
@r3545
CCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGNCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGG
+
$<2.&"&56/"!9%%7)??67FF8",>D?(7,6;C"C$%35!.3A+-D"2?E:*AH$@C'1B<5H%.?8/2F3,')?'B,<FF=,;3)2&7!91006>06E036A+66.184G3
@r3546
GCGTGGTTTAATGAAGGCGATACCCGTNCCTATAAAATCCGCTT
+
7@"(>973!-H7+#/F,=*%>(<2/-H8+!0.'.:9*(207=$*
@r3547
TCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGC
+
&8F2=85<2+*F:F2:D)F#"7EF>&3B.&H#8?6+.HE&B6%F,5$70G
@r3548
NCGCACGCCCTGTCCGGCATAGCNGATATTTTCAGGGTCATCAAAAACAC
+
+'$!!(($(*#%'%)'#$*)!$$'+*%+%#$((+%$%")$"&")(!!'%$
@r3549
TTCNAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCTGCGGGTCTGGTCATCAAACCCTTTCGTTGCGTC
+
<3#FD%-8),,331'H@";49%1<A;#D4ED!:-::3&47A@<5@FG*1096)A7#':7@2#@*@"(32<A87FH2);6H47:,E%@6>D8*9E1#
@r3550
CAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAG
+
<4H<&?B6314!6BG%>4<@"$<#9921B6B8-1%67?@*19=)@F;.2E6A?3H(:*A>;5.+7&5(>
@r3551
GAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTNGTTATGTGCTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGC
+
3&D8C0<?1-57D;BC#6)'%*'3",E/?94A#95C+)?0,+?'4-F=6"(9E6@A!79E&3-,%;DF#2)@"B%6&5F#4<-*HB"C1F((?1>,
@r3552
CAATAGTCGTAGTCATACGGNTAGTCCTGGNATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGAT
+
>?9?6>5/)5DCF5H308#F"F62F7$08')65/1D!9E+31)F222>),<0F<:1DH<#0'E-8!F@@<C362G1;739<E#G?18/!AG,@#,.)18=&+:C%A9A3H((?$'?@%3B"'>(.13H>734A"<"9#7*<)+(DCB@%3<,"4%B>/,2+3&A$#=G?7!CE'54(F%67(&"
@r3553
TTTCGCATGNCTCAGAACAAGAGCCGGTATCGAATCGTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTGCAGCGACATTCTGCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAAC
+
)?,G<?;;(@-4@=./C8/D>+DHG5;1-1<9<-+:7(97$7A5@'9B9-+$F'E(#7@!6.H1)+!&;(5A9.=>C'9(9"?=>;'G<.%6(,&:A;)1-D'09$(85#GHD74G-';/21)??72*$,?8(FDD2"&-*811BH,EBAF!E!"-*9?&,=!"-:3"#;A%(G7?:G%B95,G9204#0E$H,8:
@r3554
NAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTTTCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCA
+
%C7$@;,%0??%G;HH8<)7==#5H-7A11?>94A,.-@;EH.D8,-<*>D722C=E=D:,;19/9&G:8::B0E>$$%#,@HB%H,;@$2*E/#B*0H03,,F9:+!'"2'!8!:#*4=B$4-3
@r3555
ACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCG
+
BGBA6322!G%&E>-9<!F/9GE<-8%G=6,01/(47;C1211:<C;.56"GH02
@r3556
ATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGAT
+
>6-/H!=(;66EB"#?,$HH'=?7E9)BH18!:.3#;0#=:&C&/#D+G@6D7(4'3(+CCE233-1@6"!>4=1%&%19(==6D,G)$7E9/-5=?E:+?5#2C/@<,9E:6%1%%8:EG,(9A&)57D5?&G+%8:+E3<=8/@E,;:
@r3557
CTGANACGGCGGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAANCCAGAGATGACAACTTCCGCCATCA
+
62(A")A!!+A>A2<C9=#H/2C5<H:,.2-BA8A9C*3BG8/?H**D0$-'?(3%;$D#'B*833E36?-E><D*'+B6-F>4.F.*4A=&.4+:';!C&.98$'57C("'G7>"52*9&)A5/'@"
@r3558
NAATGCNTGCATCGAGTAAGTCGCTTAATGTTCGTAAAANAGCAGAGAGCAAAGGTGGATGCAGATGNACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATC
+
"(%&*)+)"+&'*!#""%'($'!+"+'*)''&#)(&('#%&"((!)"!+(%*)(+!+$+'%$#%'$##'"#&('&+'+$%#%)(*#)$+!)$'**(*($#+*%#"(*&'&%&))&*!(%$'##(''+%&''#!$!)')&+&*&!&!(#'"')$%+#!#)!$$&+#)))!#("'(!%!+)#'()&&+(*)&&&")$&+(!'))(($!%%$$%$'&
@r3559
GGGCCTCGCTTCCGGCAATACTCGTAAACCNTATCNNCCANCTCGCTGNCGTTTTGCAGT
+
#?.*!$!'0("C?BEE/=")')%360)9(*9D>+?D%:(H3<"(<63.F).'%(/%%72H
@r3560
CCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTG
+
G3#;'D)/$?>A7*)@?$;:&98"(A7G0+3@*8E.:!8#4=C52D(E'9.;,@4@*/::1#"<./3C+?:<#;?"&=H
@r3561
AGAACGTCAGCGTGGTGCTGGTCTGNTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTC
+
-C0D;B@%#9F,-AH%0#*97:/7=):G%2%<1A4'(E@6B(33"-8-**B*D2FA56E"*?B61<$!!8#3.=2*11.)5=%A.FD-/":8A)G,.F;(1*C,
@r3562
ATTACNCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAAC
+
BC;'8"D=6;-60G>?/F-38*A<3=3=%E.@388H"@3);5&CH
@r3563
NAGTAAATCTCTATCGNNCATCANNCGNTAGGANCCTCNGAANAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGAC
+
"!&$%$$'"#'&$%$("#"%($)!"!"&*'*#"+(*%('')"(+$"!$'$('&"%'"*&!'+*"!(($+*&%(#)""+&&&*#&!)*$!$'+*!())+%+$!+#+'%!##&#(&"##')(%$!&)'%$**+()*)(%$+%$"#)*&&'
@r3564
GTNATNCNTTCAAGTAAAGATTCNGAAGGNCAGCCAGCAACAGGCCGAACCCTGCAA
+
(%'"&&%$+"&!&&*"$+)*&")+))*')#!!%&%'+#"$&&'#$!)"%%+'(&$&"
@r3565
CGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTA
+
.C5;=(3D2.&8+@$(5H8,A;BH<<'#B@GHC(C""?@,@2DC&<!.HF#6*!!'D%"+E
@r3566
GCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTG
+
CC8G85F7C%($&5&!5G5@3%E!.+7;F22+@+!B0H(=!(
@r3567
TGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCAGATCGCCTACCGGTTCAGCCATACCNGACTCCTCCTGCGATCCCTTCNGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTACAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTC
+
<E"&G?C8*/?<G';().B=$7!"-6::$%(,)<A!;8C0D.422?B2%HC?5&'&"75?&%'G&@F,-<-'(A"1=*9(1?$7=>&0?:83+/%C;C/H;+"(8+<&3!7B+G!3F"9E5<+C4%,=D=$*($$)%(FE?4&>;%0'1)0D%12,35DB$C0(0AB!*F.@F+'C>5%&6;+9.A:5*/#&:"%)4>8,#.>8&0%$E45=A5=/;$%&90(:G63D)E<5-38)@EA,1*##FF,)(7#3-A93.39,"?&!7
@r3568
GNNCTGNGCACGNGTAAGTCGATGGCGTTCNTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGAC
+
$#$+%!$%%%'+(!#'#*$&%(*#$*&*!((#'$'(%&)##&&(($'$$*!$!&#)!'++$#%*&$#'+'"&$"&'+!")#"(##(+"#(+%(+!%&)*)%)#'!*++!))%!%')#%+#(($)&)(""*&&(($$'*&$!$&&*!#
@r3569
TTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACNTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGNCGATTTTTTATCTGTG
+
/9-F5+"#6&':%$%'C<-A',77(9:'3;;E.*;2"84'BF8&3!:G)".-'>D-G,$41<5->#4*5%;($.$/!&1:(),2@*D,=-F&%/?1/A%0D(B@1EHG!.@A3=,0/3'D%*8'F=0&&5@/%1E.3,G%2.6=@'BE?*@?<?(
@r3570
NCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGC
+
!FEE)%C1G2$!?;/-8-./'$"?H*+:5@+-A!/A(%B+#1:(+,4F8<!=$=@93+8+*$H((>#<F8E8*@C9
@r3571
TCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGG
+
&"'EE=AGBF+6*5199$9F=?*/.9!,:'2C-.<4H:.5<2*?97(4H*.10C=7H5<'#"77
@r3572
TTCACGCACTGACTGACAGACTGCTTTGATGTGNAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTA
+
.F=?5!*1D)-89H!79(%/B63AD7/*3/2*G)-.9>)>;:.FH0"@C./,$EH/@<'<.0G0(%BDC3?%#H/H<,0A,9,:9!0=
@r3573
GGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCGTGAGACTCGAA
+
9(D39("%)FC75!02)%:.6/+B)#,G%.;:4/&)GFD<@!<%'$#B."'D7#F+)2!D!.'C,1+28A$A)#*C?E>F9DA$=":8882.321=':-?::ECA!GG$1@>G5D4;%D"G1<@:G!#A7*6F6G&H*@C!>(-)#28;2&8.9AB02@26)4$
@r3574
TNAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTG
+
DC)1::?C;65C=8D;8>'B-1117(&G<(-G9/8G'<$0'8636#)F!:+6849
@r3575
CGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCA
+
@?H%&/#>:"+>9#2C'2>01%<,"'EA32+3+A*;(/AH8$?.4FFH!:9/,)1%
@r3576
CTTAACGNGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAG
+
3;42*-154#@/>:1.;5->A-CE#19G8.<4A5C6-.$.#/4=>@G'5A8FB:/D-%0.'?F#DB+8+;G:+"$=(!:&D=,&0/+*G2#9.!7DD=;.%,+BE)E'8#A:;'/C;$E688%7?A258*2#@,+,@074H<(4""7,HC;:=%(5$H,=6=1%3D:6E!,7C!=E14H&.+>;)";8:6/A4".C*1@1,F69AGH>9'D93
@r3577
TACAACCACTAAACCCACAGTACCCAATGATCCCATGCNATGAGAGTTGTTCCGTTGTGGGGANAGTTAGCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTG
+
A'=6""-0&G$'A7'F-5?(:704;)-1#&FA0(2F79DH52=F?5680!>H89@=.8576,67?%4&H(>A$E964F.=)E9(H/&+=%H5:<#-=&12H%;:*>@E65&:7@D:.410G&")+/<)&@0C!H0
@r3578
TGCGCACCAGCATCCGGTTGTTATCGGTGCTCANGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGA
+
@@&>9;4-7"!8&42H<5/)9;;,/'%3335B5<0G;6<&A9/<(D=!5%AGA+#*C<>.=4'(07B33:E.2*7!"%$:@09!-')A1!,:81?77HG
@r3579
TCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATT
+
FA/82EB1@.1D!A97)-*A'/!,)1/!*:A%'.B%$?2E>G8+);$
@r3580
GNNTATATNGTNTGGCTTGCATAATGGCANTCAGNATGAGT
+
"""'(*)'"#$"#+)'*%##!&$+%"(")#&$(%'!")$(%
@r3581
TGNTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTG
+
$13-B;-2H!,54G6(&*-7"4E8GD+/#G$E38A5E=,E&B!
@r3582
GCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCG
+
"&'B#5":$;35$=&!BAB8#'**1B&/%=$0BHB,&B,899%*5&%9.>'0E#+@%B-,C:6B4/;F09
@r3583
ACTTAGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCC
+
=2DC)F:/&.D&2.=0>/.(1624E04<AD4>G<D""+A4'<?5HH==5)918&AE%@7>:<:;;/!B6:=4-4&A$FG>B%8.<#15!7H.A3.H=2!+".34$=*9,2
@r3584
CGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTC
+
E8@$1*=6BE.43:3G9>@>#A/?535&3"/#*#/F4$-,0)%
@r3585
NGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGTGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGA
+
%=2#E';+B%*C",0*&F,E>:%BGGG<C'2<.!#8=C9C(,40%-28%&7-2$/4D221?.C>+,35D?.;73.8(@:835'5.*4-9!<4--3A24%6E8#$=@+"=;D;E"3GE;2"%,-A-6)#&5*$C88)4+=(G@>+!!A@,A8HH=:&(:C+;;?A1?/<G-.'1.''@F)C51.?(33'AA-7H%)1,;72</D2;=D3+CHE>?3H2B2D:7>&?%@#2+A8<!E?&!&&+*H#$2E:38A/3<323B0';4*%;;!G=>')H0"%:<2'=5@73,<?"+G8
@r3586
GTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCANGGCGGC
+
/(89?((5?8,A#5<04.;F1D#-2==B6,.F6G&86D?B"F?85:%0;E)C0H8F5/.C)'#3?-'+:C)?:,)6!:>HB50C$3/<;G.)E'?:C><$B4+6:6C!%<3AC16F6FB$F;HC%7@"B0,54?:<@87%:BC94!E8:+*/B11.!(/F969:=836&82F>(%+/&10?>19&:&2A#-+*%5@07780"-'2GF#'3&!G#0@%/6+<=#<FH"(D>>6H0-2%047($#/5;9@7<9=&(F!?-'20H<.+$&*F7)=19EC#8>5"3C'+548CD
@r3587
CNCCGNGANNTGGCAGCGACGCACACACNCCCTCTGGCGNCACCGGGCATG
+
(#*))&!)%$+&&"&+("'*'+(+&$&&)#"'&*%)((*'!)!!$*''%(#
@r3588
GGCANCNCCGGCTGATTTCTTCGCGTCTGCCNTACTCTGTGCCACCANGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTC
+
$&'&)&!$+!+#+("!(&$(%(#!%'+("&("""!*!"*)$')!)))+(%($'*"("($%&")+#'+()#!(!)((%'()%#%('"(#+"(%(%&)(&%*!$"%#$+$)$!$*!*&&*((
@r3589
TACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAA
+
%?AF%"D*#C+D,18.,?AF5%95.@@G#7@)613;)E%9<-'!/;E:9/!=5(41F64;7:!.3".2<&G"@C(
@r3590
NATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTAAACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAAAAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTG
+
!B5-<#C.<8D:+3.E2&F;75&=)',3;?#A!FBBH62"!H91;)7!)7BA?$2?-GF;7>0@6>7C07!';D:&6'3;@B"/'DH5"3@D7B80!90&>E%(F3GH,.HC0FH2$619$,789(*B7?6A:D35:!4".:"CE82D,'D45)*9C36GB+11#-6-.B%&#E7!.?8.%/HA;5(0F*
@r3591
GAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTNGTCACTTGANGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTNTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACC
+
;#*2:#9*E@8",G1!H?-,AE:+8*C",("+'D;6(,*F2'9AC/#.+E2%+*?=*+B%0>#-H:.911G.:70CHD7$'@GGE4@0+G@)0D4BG?*$#?7(="*E(8C9-#=1D6'@=9:(:>,7C#:''".H$;%#4B%32F""H89$?B)269>4B#=.#6&9)92D!6476C1A8"D$<A(D9E;:(*B=(80B"D,;,2E=9F($&-B&921#8%%;1:
@r3592
ATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACANCATNAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTCAGNGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACNCTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCC
+
G6011=73D-89;D!>-79-1.CA,"-DH5H#?@*5D3,4*8/C6:'8E-5+D@-D6713*@93>&6G%G/($/.F&D8.2@+$;B59<4:0>21C=%;:':C>#.0@G<D1GF4@6<6GB/;FD=$.4&$95!"">>$#1F#@2-:=**+1@2%"7678(B=B/BA>#-'6@B+/1*3>(007&+?9B1;*!!<H$*A34E&HF&G-86(;8"9H8*)B/465(/?<<'2=G#=23/4/42+7507'D3@DB5?#E>GD)G,;A(;D9<F"=+F/6=%:2)E1*.#(9%DD"4DF,857?@9%3!4,)@.&*G=E>E6#5,-,2B8&H+4048:DBE+6,5A!:AG.FDA9D'+;@!D0":+()8%3HE)F:->918
@r3593
CCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGNCGCACGCCCNGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGA
+
:E1#BC5,3#F4=:":58,'G3'A9C@%F.02*6E(A!&87+">GG<).6>B"'<"93116=E6C(;;.@45)G$E?H3%CCF6?*2#C;;F:6:2,+,;-EF@4--?94A'(?#9AE0,2,7,-;53?:%"?/#4*A"G;3<<=C0*86*,.>916"!E@8,E%"&/.HE+?AD%3;3-@?<&(G/=8$=:+,<C.*7A23CE1D(5E#A)'0B
@r3594
TACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACG
+
9.B:@+/'01?D5(=&4$=/<.-)&54'DF=941;8E">?"#&G30%F92&6D?4@7H1GH=00!/'>'9:AEC#:79'2<!,F(.-C6(A=H,)*3$::;'7..8$;),7"/G*498CC*7295,C@C,$E)40!7+(F&*&?5'G-H'+260#2>D.(+,FFH,?"%+,?25<.4E:+B9?",9%B="-)$2'7D'+&)7FE,$!'53+A"'/">H2G8=F=D):%9B0+7,1/<E8=<7#4:H#=DF%EAB747>56*H2;H7-#897:#9%8*0:EB:928%!244+=>1"7D71+,F)0/$<3>/H3G"
@r3595
CAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTAGAATGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGA
+
(B":75FE,H0#*$<#<H9D8>009#;&4$@"&7()48&-9$<$:5993669*A36<31@EH+?5,=-&=E-?2@0;)?F$>,8'4+D#EF;0DE(!+3G;E@?FF#5*$A3=?+-;0%)G6F4G,+C8*H2;!;)&(+=07<#(:F1,(5)G>G@-+,&#<C5,-1D5!F:?3BB.-B2B?D"F)+%1?(4$/10##A+#@7#4/$97
@r3596
ACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAAC
+
0<@>05D,:B"#<0.C6,/(G$E9GC'2!.0??5$/7?5&+0!A,4A,%$H5."13!,7,%8+/.:)F+%%611%-$(-6.00D>8"AF#FD.=40D''B#0D8C#<3C10:6//C++<2A@*:2@-@-0<3"&>3"E6G";#+$/'E5D0<<AG3'@=>),EG,5;F."9))&;3C==?!"D
@r3597
NTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACTCCGTAATAGCGATGCGTAATGATNTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGA
+
!H*6&04<G3$9.C41H%!B%<"$BD3+4@)9'A%GH3=#+G4,9;.5"!?),B#307C;E#//()6H:2:>!H=$G0BCD38<54A6"F)&>56D3#B!4@7:/(=+?*%G77;A@3565&4;%8BH!A=1-:D;4++>>-/0/2/.947*?+(3E>*?01?83&D###B7B4)642?.!>AD1-6F8$;
@r3598
ACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATACA
+
H98G'E320?0%G464H0DD<8*>5!B7@C@=.1B"3%A>C.6EA)'97A&55+H69-G@70.-,737/CB
@r3599
GCCAGAATTCTCCGACGAATAATCTTTTCTTTTTTCTNTTGTAATAGTGTC
+
++'))$''$+"$'+$$$&&%"'&)#&("(%'*(+#%!!&#**%)!)$'$!!
@r3600
TGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTG
+
G=?3.*'"/$#HE19D%4>*;+@?-#D)0!H'4#"7+;:0D%)B0D)39B03(<F">-.$>
@r3601
GACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGNGGAGACA
+
-!%>5>(3$$.#(>+8';/)87.@?,&A+G4?,)508DG$"*A8E7
@r3602
GACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTNAG
+
@1F@=2&!/$9>/7$&=.2"4:2EG06E5"56)G/&!A8EA#%C%.7=?#;;C,56B5975<9&:D!8<B&,A%D)1G/!.5F0,$77&4/=9D5H,H&E2,H9
@r3603
NTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAA
+
(;AG.CDF:2;1>$/*91"*/$"/A;$,B1BD4H1.34;5E
@r3604
TAANACTGTCATCAGNATTACGTAATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCG
+
*%("+!*(()%+$'($%$(""'("$&&!#($#&$+'$+!'&(#'$'#!)''*%##+!$%)'%&+%!($$'%#'+'%"(++&"$+$%$&)!
@r3605
NGGTTGATCGTGGTGCANAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTG
+
"E$!12<:>3+#*60!<D/%F:<;4$CF:+6<A$0C#1$%=0(-34<;E%+:(9$7#F2+3D'16.1*A</&"<G"F>,4B0=+4/A:,5DA47;B!//H*@#+HAH(2F8$%)"CB;?D35==4<E1#9
@r3606
TGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGAT
+
C=":=+C#F6:A$#G:G+CA(91C)@)B+):>->B&'6%0G'2-+2-
@r3607
NNAGCATCTNNGCACGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCANCAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCNCGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTNCGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCC
+
*$&*!)'*#!!#*('#+!&&%(&$)%#'*&)$%$'!)%+++*+*"&)!%!$*!*''!!+%!%#!'$&##"%"(#+#*$&+"")$"*#%'&!!("))$$)'+##*(*($"%!*))"(!&*')&&!&*()&*+%"!'!**'#'*&!%(*%$!*)%(+'#&!&(+*%%#'&$&*!&+$*%%$'+&*)*!&#(%"&#()#%**)'%(*((+#'*$&%"$+&($!+&+#)(+&+%)$)##)(#)+&'%#!)"*''%#$!**(*%**!&(+&&('!#*&$($)*)))
@r3608
TGTAANGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCANTTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCA
+
&"%('%'+&#+!"&#"#+##!*+&)$"*%!+%')"'%!'*''(*!(!$*)#!#)""#(#%#!#*%&&)$)("&$&$"))'")(#$"%")#(+"*)++##&'#*%#"&***###%#&+))%(+!!+&("((+'$$%&%*('*%%#!)'($"&&
@r3609
NGCTTNTTTGTTGCTCNGGNAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCGGTCTTGGTTTGCCCAAAGCGCATNGCATAATCTTTCA
+
'%!)'#())%**#%&(*%&)#&*$+*++*)(%!''!+&)(')!#*!(#*!&("#+!+!%$'(#)#"$+""'($&$&)*"$"$&"$$)$!"(")!++(*(("$"'$$'(""'!'(&+&***&'*'"#)++%(&"%*+')*!%&")%$+##%#*&*$+")&'!%')"&$%&)$"#
@r3610
AGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAA
+
,EC$=%#79'B0*6/.*CEB>!;):;8@,6-03*$"&11B
@r3611
ACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTAC
+
<D!)@H.)B=0%,G;.H.E9?166$3(%/+*EBB*0>->#5
@r3612
CTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCT
+
B9@$FE-$H)?&@)E=EC@9.B808<!-&+;/(6,*#F.@"<:/
@r3613
GCTCGCCGCCTTTACAATGTCCCCGACGATTTTNTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCACCGCTGGT
+
&=<H0$)>*/<:$1A%.-A61."+:2.(B&H.0'EE-(%6G;4%81;A@.9:@9=9&8ED+93)B1C60-@':7.C-<DF(5",=95!B,,@;D=?$142:3#+E9-$93#D7=!E.?F?$*.#FCB(/'CB&2/3@5'<+!H>C!:&@95GAB7G&?87F03"4!18&C:DH1F/H=0HDA-*@%G8/%#:
@r3614
GGAACAGTNTGGCGATAATCCGCTGGCGGTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGG
+
1:"%*F,5.2?!05/CE<#F+4GA#B+11(?C"%=#"-'(F9E-.?=8$4(&D?5HC9C(+#B%'!E49E8-8><8G126;'<:H$0(
@r3615
AAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGCGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGNCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGG
+
G1/6<=9:?(/)'H;-'9AG!/=D;&+B4+.A29G)0!."C)=C8.?-1D=&G-84+)$:F2=#-H++??2D2:&>E<('&'=<7#+("&)BBBGE;:6>+;*G.'-D.6@0456-5AA!9(1$*A($C"%,/H)8AE6/01/EAE='/-7;7;$>+!&>?=->F#&%@D700-<=$>?"&C;:H6B93D=@C?=#2A>?13/C/%#GA7)2::
@r3616
AGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGNCCTG
+
+)$+*%%")!%&#*"&)'+$!$)&+$#((&(('!(&($$*#)()$(%$'
@r3617
AAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGC
+
',6/D@<F.&8()/2+*H-.C/=24+<C+9!3?/#F%D(</4F"(-0!+7-B>E$(DGBAE(;9)HE!(C=:,8"<;E==F?1,F-GD$((
@r3618
AAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGA
+
(&AA=9319;7=(@"@&!=3?1H>54C,0$!(@3=+4'1+C?+E->8D)>6$@E:H>7$*2&C-:G0:C'%F?=</4>%*G.7D0C??$6E;1C4A-''F%8@(D""C-2('8.6=,=.@-#G36>C(+:,E&G*4)E,,GA;,?$5C<,D7%7>B#.
@r3619
CANCGGATCTGCACAACATTGATAACGCCCAATCTTNTTGCTC
+
"*!+*!+)$#+("+%$+($'+%%#)%'))*+'*"$(*"#&%((
@r3620
CCCGTCGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGAC
+
GB3EF6H#'B9302-=;05@!B8*&#2)+$*G:0,3;G5<':"EA#G(!:<@%A2?D<+EAC.(E%D>EH>3;:$/2,1F&"*F%$/*871191/+?030$!>A/=A1E+G-44
@r3621
GCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGNGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGA
+
8D3/(21(HE>*%,9/07'"4>C4*=0"2A,=@3;%8#)8>$>@H/<E)A&5$!%%6=G'#8>(E?D8B(-B(H?9!;$*31<;H*3%1;'>;C@,)#+4464>8%;/=#5@3D2=>@G*2GB<,"6!D
@r3622
NTATNCGCCTGNTGNGTGAACGTGACGGACGTAACCACNGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCT
+
!+#)&"#($!&+%"'#+$%!!")))''*'')#''*&&"+""%&)!)%")&$'&(!)"!)#%*"#"#%""&)#($**+!$"%&&%
@r3623
CAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTA
+
4?45B<B(BB1-5D4B&24C%9C-!%6/1=DC+D+),D,;5'!
@r3624
GNNNGTCTTCACGAAGGGGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCCGACACAGATGCGTGAT
+
)!"'+()&$(+"%#$#"*&+%!$+%$")!!')#*##&$+**($%'&#$*)"+(*"'*!'!%("%#$$&'"%!*+#$%#&&(*$("#&*!"$'"("!!+#%#")%$&''!'('#$+%%$$"!('**+(*$%*)'&"*(*$*$#'"'$(*+$+)(!('!$*)*)*+&$""'&"++!#&+!)"$!$$+(#)!+%&"#)+"&+%)!)(&"%$#*"!'*)$%%!+%&$+()'*++%*$'&"&()(#$((#*#%*!*#'(#)#$"+#**'
@r3625
NTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGTCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTT
+
#G;.@@-+&&G##(5A?F*<D(A-F.=;;0G&@,;E&-#)E:3.FGAF%=-%&0%<DG*<=!B7$36A.?-'?"/+?AE8?GA3/.#2.8$=/,2+HA2C:H.=?8F=7D")288*.:34<-G#
@r3626
NNCNGGCTNANTTNGNANCGCTTACCCATCTCTCCGCATCACCGTTT
+
%"&)%)(*#&"&&&*%(!&(*&(%)+$)&'!((%#*&')+*+$#+"(
@r3627
NTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTNCGGGCAGACCAGCNACCACGGCAAATCACTCTGCACCTGCAGCCGCAGGTCGGCCTCACTCAGCCAGGGCAGA
+
(+')&+"*#)'!+#$*)(*+(!#&""#("&&)!'&&*$&!!&)$*!(!#""(()!$"+()"*$&"&##$*#!(##)*&%)#")#($%$*&*"+'(#!($&+!("$(*%!$)!"#*'$!%)*$'!'(*(#*"*"!%(#%%&&$)'%#$!%$$)&"&"%!'+#()!'+$"+&$'"%+&("#!#+%(!('"%#$"(#+&&"$%)"!)*'*#)''+&&$$#%($$+")+!)((&#&'++#+"+!)'""+(%&&)+)!%$&*"(
@r3628
TGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGNTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGA
+
CG#00$?0DG&75@!..1+?,A246G%(3+:7.!)*<6:E,/7F!&,B)&/1&%1-5E7&?52.*.=4A#C/<%=99=#+>2D-556'9)&"+#48C#46#6.A?8;$*>!1;6,AA6@C(+#'3-D"GB,-"38D@7"1'D-!!?C>G.5.#%A*C;<5?5H:G'B&*9'")65749CF7(5/9"*<7=&2(:!'("&+:6@9)$B)5GB>F03?ED4E3A:;6)+<;!91H)&$4?8C94<!F6?@!58.1,#:$2DG/H6;+-*9;8>:06G)4'6@.#43.!4)#3@DD7B-069C076F>0C=DD&*D&A1+:)6A+A4FB)23@7(1"93@78.H;7##&-@%'7?%;<BE.:,4@1!9:H8%<+(!
@r3629
ATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTNTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGG
+
G60#1D<6.F-E340=DG/1E::(;>##F)-'F,??7ECF-,D/,/)&A*(+%30.FC0A!-;="=:$H??8EG$/.B40**-.'!=&161$03=E1(.394-:@B2)7>52&'$2?-F%+<(;1?,C
@r3630
GCTTCCTTCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGA
+
5&:"!)E<&HEBBC@2(65'?5B@8A2)(GG(=C/99":E*.7D&G
@r3631
CCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTA
+
=G(40-?,*GE?AG)GAGA,/=/,9F.#-%4$1E.106=4!C$233,-9D>BA>F>-==")/&43>6G#1!(*=?=AC";F5G/EA:
@r3632
GGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGGTAAAAGACAGGTACAATCTTTACTACCGCAATCCANTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAA
+
E9"G@18;G?223+A0;D6""4#2F7H4;G8&H;C/>4!.)+8G5%6!@,3+299H*(H.3D8F1=A5;,FA$=%,(+A#DC(=>;:(D&+7))G%323%@FD;7&#1'11)=12;6E">:"94G"!!!H#$>#;8*$2%;
@r3633
GACTCGTTCGCACTGGCCGGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGG
+
H*?.>!=0+H),A%GFC04-?C'-=:@B2=A,1-8G8!0<A?245H@+2$D955
@r3634
CCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAN
+
;/HG9;&B=/-E,&E+!3GAE%EA@@1(!7=%5,C1-22*B.F/?DB
@r3635
TGCATTGATTCATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTN
+
'G42.3"@/.=H?A99+GH</@+FH$):!F4"5,B(>::(80,1E&%*,>F=3C;:D=9'D;A9?H13DEC5B3)46HD%##&"E745<&+3&*2B<A&919'8?4'=/?%%H#8'CG-$C=9E-1(6H2*12'5=:HE5H>
@r3636
NANNNANTNTNNNGNCNNNGNGNNTNANNNANACCCNCCCNTATCANNTANCAGNCNNNANGNNNNTNCNCCNTNNNTAGCTTNCGNNTANNTNNAATG
+
!!!#!$#!"$!"#$#$#"#"##!##$#"!#$#$$"##!!##$""#""!"!!!##!"##!$!#$"#!#""!#$!###$#!#$$!!##$$#"#""#"####
@r3637
NNCNNNNTNNNNNGCNCAANNNAANTNGNCCAAGNTANNAGNTNNANNNGNTGCNNAANCGNTNNNACTGCGTNNNGGNNNAGTNNANGGGAAANNANNNANNNNTNGTNANGNNNTANGGTGNGNACNNAATCNNAGNNCCNCTNGNNNCTANCNTNNNNNNNCNNNCTGNNCGNTATTGNNGNNGNANNNCNCNAATACNNTNGNNNNNNGAACCNANCTGNNNNGNNGTNNAGNNN
+
"!##"#!$"""###$#!""$!!!$!#$!$#""!""$!"!$!!!!#"""##!#""!$#$!!#$!$"!!$$"##$#$#"#$"$$$"#!"!$""$$$#"$"##$##!!#"$$"!""!"""$"$"!!"#$$$#$#"$"#""#!"!!$$####!!#$#$!!""!##"##$#$"$$"#""#!!!$$$!!##$""#""""$$"!$"!##$#"$$!!"$##"#"!##"!##!#!!#!!!""""$#!!
@r3638
GCGCTTACCCCAACCNACAGGGGATTTGCTGCTTTCCATTGAGCCTGNTTCTCTGC
+
2$FF+"7'B>AC#%2>H#F-3@A<;..=8GA*9:8:CH>#D:+8BB@10)&'+!9E
@r3639
TCCGTACCAGAAAAATGACGCCTGACACTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACAACCATATCGCCTACCGGTTCAGCCATACCGNACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACNCATCCGGCAAACCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCNCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATA
+
4?*:!6/25A+5&&>C5'""219=G9E3D+8!)&3EG3B5%0(EF.BD:0/%(?!"/1BB?7("(D88.D+61B;1=0..&7&'0G+/$"<3#9F<B(40.<$#<21/>?%$%'@8G.G&4@#:#H>?H7.,(5#+%E,F/*+'#>&>!(,DC.=E$3-.,$G29)8/@!!%"(G-:2B<C.9.896E<6#D('H/D6)%0=?*88H*3,EF>$:6C?&8>>H4&76!B9H+7H<0'5>:."*"9)5@+3GE9@7"0HC%,1F.7!H+).(B/<!>!.34&5%%;8,0%F1,9.81;!)$$3*24:G)A06CA>6*;#,
@r3640
TCGGNGGCTAACGTCACAAAAGAGAGCATATACAGCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCC
+
(($%*&!++'!(%(&$")+")(%)++++*+'+'!*(+**$+#(!'%'"&'*%&(*)"%%&')'$&!'+)+!$&&!)
@r3641
TGGGCAAACCAAGACAGCTAAAGATCNCGGCGTATATCAAAGCGCGATCAACAANGCCATTCATGCAGGCCGAACGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATACCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCT
+
17&%<&)&H$31?=D647?+5,->A95))D=6@<+1FH?&4%.#C.,/66!=),<+4.7=%44GD%G-D=>C#<3=HEBF+108F+?B!BA/*,&4"3A.)78>GH&7C'!'0=(>>.5,*"0!;#E2/!*%;06<,(:2'/%A":G=5@)4>#.7F.,4<=$B7>;<)$*-<1=79$&4H02/79DD3F5@.GDH2BD>05<'(1,+A)9$";1<6C
@r3642
ATNAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTT
+
DD!1)(>**F,B:4#B=)(C2%#D*-.?8*-,.5!&0#:;$/!47$BC-4>"*:F9(C3.-=F@8G:
@r3643
NATCTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCG
+
"9(-B9C9#B'H$7=AAHE/@7694B&8:FF;'(9E)B1:=='4=0*+34&+7&7)",@G&2$6&G1(?;8%9*>*"HB2(A-1D@%HE2"/C!'2"3*@((:$!$&;:B*E48)2!%'B.21G,-6=%-9CF<#)3E,D2*:24/7(16.
@r3644
AATAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTAC
+
D>71">D?$;F!@E?G,#9?18,54/C;G@#($?22+673<8/-<,#
@r3645
ACNTTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGA
+
)GB>$&>G@4*DECCA!F!"*..&(+#-'HED0F940*7H;'1=<%/DGE&&<=27)5<,A7/5+
@r3646
AGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTNATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGC
+
'F,@4&),8!7583?.3-=3:&7;":/!,>15=()!&4-5?;AF+18GA54:'=(C'!2E@D7'6*C5AFFF')+(630'C*H2+GC/E(05'D)1/:?&E8''16G,7.&C2(8)/-(1#.F1D9(FH#A''5B1/5+&*&4?3*<H::C*3;*83(-(*/E'H"43+<0!@4*#'E(#"86,'E;>AA@4:;A,A$31<#&73.%&(*0(E)7!;<7'?,$=E"3<8-*/7@+%6.<)C
@r3647
CACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCT
+
1$D=*4>EE:.#04@5C(%@D>9EH+B.5E"0!C4F(D"6
@r3648
CCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACGTTTGTCTCACGGGCAACCTNGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGNAGGCG
+
5>5<9,3<94"B0=.G,6.B=):#G=+"5@43':)=D-$C6B8DH*'-,:H+D(6:4*$0##7!36&C.9&E5$)?&-07)*4*0?;&77HA2,+A$G!1C:-/(#/$7408?(F8&D)21:69>5+C>$#+<0G("+1;D'+'5@16;EH=8"=$/>6E8EC=B'#=;C(=&@,$>H=<$)AC/8H(;89'%A:=H-;E7?&$'"04:!"'3'9@E"@/F(B=**=E)8)64)=#;?!0)7D(9D><!8E-H)<(;4;$*32B(45G,D+@;(GE,-@$;D5B-"'-BF8.1C!"3%>1%'6<1-.A>@B!*?$39C&:B"AB*"<+$'&4+BF?:=7#<(&A6'>
@r3649
GCGATGCGTAATGATGTCGATAGTTACTAACGGGACTTGTTCGATTAACTGCCGCGGAAATTCTTCCAGGTCACCAGTGCAGTGCT
+
C?.80-#F#>%?6)D33<E6C&8>5%H<413+?$#<1/F1#)0$)5;=)BD7##?+4=8(+8E&6/A(+A#B+!B$;1A4D(D*B!
@r3650
AGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGNAGTGAGGAGAATAACATCACGCANTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACT
+
6:FDG;2%8<'(3".':6G$11%E9;$-BCH3+*G4D'8%7.16*3&!G%;@CB:?0%C*4$))=8*5,/12<06(-?;=A7<$;,DD04B#E;==%D:GB8C:%E@47B&+/;$HF(@81A62@85('64G:3A&,?1?.A<2@)/@3(#.1D
@r3651
GGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCC
+
29-B)>8',+38F<9&&/@=##H:-#>2/->.+!5'GC)&47+4'G0D*'6;<B788<':-$8=<@=97:D!2!9?D#"5)B";+$8=9&892!F(<776$AG$7)=G&%3F$@-+
@r3652
TGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGG
+
386C(5E="%$&&!>&@;61$';&1+F,7=7'#>/7E5#:4>94!<8F/=&4&7;;AG@!=!='9<F1(4!),,?4
@r3653
CACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTC
+
0$;F9>#&3,1/$<!H?1,18#-A#%GG%!>2?=41%,G1H13",EE,)D!)@:B=0>/A5:(7<;7G6800%43A"(-??>"1"3$.4D76)?(2,5@+?->
@r3654
GCTTGGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGACGC
+
G#<GFF+.21=0//"*B54H3-/;<)-@$!GC:<7+.B!#>D,A?%A+81*DA?;@>4<E83D919C?H8-3DG(%7/?7"!"-;#1E"#50=?;%1;+*%4,'H@E0@!@<+6,#A0A"#<-,,?587EC#>7:45=,*B3@!3+,'1@A)G7D?"</9C9!=!F/$9:=)-1,"8>3=*&BA%&.
@r3655
GTGAAGTGATTACTCAAAGAAACTCTTTNGTAAAAGTNATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAANTCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGNAAAGANTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAG
+
+)$)($#+"%'#%(&+!)"$)+!#*##*&!*!'("+*)#"+*!#*$*')!%%*!!&)""$&+""$$"'(##(!'"%(!!')#)&"(&$#(%*'#$#+!*#*++)(")%!##+)*"*'*%%#$&'*'*#)($"#"#+#"#+#($'"#(!)$%"$+&##!"'"()'&'(!'$"!'"$)(&%(+(*&'%!'#&!"
@r3656
TATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCT
+
E(1>?'@?:F--?99F@/C9$B-*3D9/;"(A#';?5)H+@F,)G':4385E!6::+$(/&*;43#*@B@F)
@r3657
CGGGAAAATGTGCTGACCNGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCATTTGCATACATTCAATCAATTGTTATCTAAG
+
D%8(7G,3-H0'6F9;0EE658-EG-?D#;%@;7.?.9%%H784<7)HEFF?#D"H(F6$;6$@76-H"1(@,;CA*:!7-2'8B0B,4%&H!C'<F<+*@D,'$D;G#?:&E=)';'/>+9B?*-"DD1;4)E!4#<A+9%&"8=2D6G6>.&/7F"8&4/565+25(-4HB9F
@r3658
TGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTT
+
2&H=-;%1+.%F-A0<F03B">!4$3.$%-B&D-G>C?")FF(3(D>C=@:H<D.6H;<4%#14FF68
@r3659
NGTNNTTNTNCNTTNCCNANNAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAACCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTTCTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATC
+
*!*%#%%#)!$"(*&&$#)#+%!!!+('#+%%%!+!'%'%))$*$*&)"$$(*"("()#"%$)%$%*()($(%"$&"#()$)%%))%#*)()*"$)"$'%*##%(++$**"&#!*%"!%'+(++(#*!#$%&!$"'$!((###!'$#(&+!((''++!%+*()""""*++++!'+"&)#%+("%))#)!$&)#%#
@r3660
ATTGNAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAANGGATATAAAAAAGGTTGCCAAGGATATTATTTT
+
#'()!++"''$%)$*#*'%%*)'$"$*#+"*&(!$*&(#+#+!*"*&$"*%(!+*%''()("$!(%*#$!+'%%)#)*%!)*+%'!($#
@r3661
CGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCC
+
EC-,>C30&--2!H===.GE.G04F+;B%!4'?=,G7!%0!G4DD'!)%*)A@"?B4:?%-$)3?&2>%)"B?1>GB*ACC<*-'9/81.
@r3662
TTGAATTACTGATCGCACNTTATCGTNTTGCATCTTAATGCGTTTT
+
B+BG/34":"2&B/47D%,'##<1D0A%*@?(0$1GBFAH)+1G)&
@r3663
GCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACG
+
=$1/*4C(/E3(+:#6/64971!35."<96.=4?E;*=8/E#'6A*3>5167-*9;E&/D#A2
@r3664
ACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACNGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCCCCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCA
+
7$;5!+"5GA461G+!C8>"A##3;?='<G5$G/&4+)4;'A%-C&?B.$9DD07'73/42"85D57(1-=F9>G(*DG<+61-8%A<#?*%B#G,&@7@G'%8A'+94)&-)G>GC%;?D7.<0?77#/CD+>("=0781,.@9"%1>1('?(DD>.>37;$A;/:5(D#2:,.BAC='%6.5;D%/.:,E,E,8+H#40=
@r3665
GNNNNTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTNTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGA
+
*!!#!+($&+*+%&#&+)$++&%#)')"!'$!#$*(++"!'"+()&&%""#'"#()(#"*)#!&)*$&(*('+!(%#*!)"+$'%'+'!%&!'%%+'*""#*"#+"&!+!*"(#)"%%+%%*+*%$*')*#&*!&'$+#%()(')")&"%%&$!#)&'+%!"
@r3666
GGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTNAGTCTCTTT
+
F>=)8-(BD+C;11&?+:7$=&#037E32;;@F8:,,1*06,6CAFG9!C0%F9(@@CE1$G?2G
@r3667
TCTCATGCTGAAAACGTGGNGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGNGTTTTGCCCTGAAACTGGCGTGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTNTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGATCCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGAT
+
@<@D5DC@%%%A4#?+<<*8:;:68=B*<1*:>)B%5H;1=12G-#D(;?D-!?.88="=8F.H-"<E$'#:&EBB=CDH%+BBB6!60>/9/:2)A!FDC#G3E$4'3>9?"@174-7<%ED"40G2E<$81)HFE/9@3/:(+,:F!C&,C=*&!485<"!?G8,B$&@0<9BE6)91"H-6"DG0GF(5D+436DA235<H#>BCD5(3$1:&E7,E%671A)!?79=59.$70H.H"1/:<5GG3!CGC0<8F,E6>&+0;*(('A(H@@A6E.%*-7:661A07B9;1)?B:H1:8'B641,!E0$EEF?)B*"7%#$*$<!0+91'2;".=E'%9>F3DB>G7$@?*.94<=A7+%7DH=&@B0;*2H%H7+407C7?!#>4BDH'$<96
@r3668
GATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGAT
+
<B2,*FGD*15@&8@C!B8A0;46,&E72<A66*305G+-
@r3669
CAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTA
+
C+3%E8.>,-2>;-1.8E':9!*<1?7E!H3F0!%$?$<$5.8>
@r3670
TGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGG
+
C0&663C;+H8+H,#;1">)2:8A"0(;B"0B/)9F"1*:+&,+"6B7;@&+3C>B.3=0,+(@:AD50=G@,%=E4;.C#A
@r3671
GCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATT
+
A5-E4D(#2E=61'7!4"AC"@*/59H!00:!9:+"%=D)8"6%8C>""-.5ED0!416G.A/7"!%C)'BB627F@,4#9H
@r3672
ACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTT
+
)6-,)=B*H3?0GBA!@266>!H.-'0DG*':>#(<H40''B79AF(36(/!'-6497:A%3/63@-
@r3673
ATCCATCGGCTGATATGCGAGGCNGGACAATCAAGGGGAAAC
+
,225@$8-)E#1G+!'?B=A"+5=8==";3$DE";(/=+G@/
@r3674
CTCGCCTATTACCACAAAGCCATTCCCGGCAAGGTTNGGAACAACATCCNGCTGCTTTAATGCTGCGGTAAANACAC
+
EH&A($?A6$*.>C12E$89(,-;F>02'@(6%-)BGC;C@F,2-517AH*E2*C2D@)1(%;'<)+279.:8BB'8
@r3675
CGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGNGCTGCTGTGCTGTTTTGGTTC
+
F)@6"B>9>7<;4D(5711)6?8''4;01+@F@/>:7H6<4;4!7A8"(5?!2D4,C7&0.E"D2B?"!3
@r3676
ANAGTNNAGANAGACNNTNGNNGGGTNNANTTTACGGNNNCTNCC
+
$!)*'"(%''&&%#$&#$!*$$%)'$""*"$"")$%"")+""!#"
@r3677
GGACCGAGTTCAGAAATAAATAACGCNTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCAATGGTCT
+
:,73-,*'%:-C/,5CC=36"3%3..5G>;B"9*!3<,-:4"+85(/6*/)!=@D5-"9"$%&G-!4-<
@r3678
GGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCNTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAG
+
B,;;G:B3$+=+A37$1*F"$50)-'%@&/.*.<$"0$<?,CC1A<A09"?%(GC+<G(#8@.%H&(A,4%".#<DA);F$%C(G?/.>(@D"=%;G!:;6@,5.%>>+9-?E>59A*+6%@*$,.+.+E3+@($*1&..60?"3
@r3679
AAGGAAGTNATCATCCGCACGGTGAAAGTCACCAATGTGGGACGTCCG
+
*()&)#)#!#+#"%'")!$'(*#"*(*"+%"!"$)+&("%"+(!)+%)
@r3680
CAATCATGCTGCTAACGGGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTG
+
?0%,E#<F5C6D9206)&1#*E;+)'(8>4*>+!91?GB<*6F@"2<!%DG-"05G>F&GAHF-?4C6DD2#E(8:/EADG&@@9/B5C&HF#B&)C&A7&*="%7,A?@(B7C!1),?
@r3681
CAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGC
+
H>2D*/;5A),=$4H(+>CE5>H"-<<FDA*B5"5A4$@1=<"EDA82B"F5#G?7&=44C
@r3682
GAGACNGAACAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTAATGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCA
+
'#"*$%*#&!+*+'!+!*+($#&&#*)&$%!("#'$(#%*)"()!!!%&")'$$!*$$(+#'!$&*#'!)((!+$&*$'#&!+%$+!)$#&$""""$++&&(&!&+*""#(!+$!&*
@r3683
AGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCANT
+
<"<1@>79:$A!H/?()>F4A,%F*F+*/>-;*@D-2H$$9=E%!B/,8%=.<A5@1'/C,68&(8'1(C,':!&3/B!2;*0!C=
@r3684
CCGTCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGT
+
0,63>,G3.@5A--;01/G#&B66?(F9(5)+<$6*@'$HB5"(4*%D,6C"(A
@r3685
NAAACAACAATTTTGAATGGAATGATTCGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTA
+
)<6G?E&!GG#FD@5&2,:)&/G+<',*'+>A/))</..0CHFG/+!7?(!8,5=/AH0):0;DBC!5*(=D&B@(+!=-2)%""%'-52C372@;3")A%"#.*+"@=?AG>C+21=,(10&FD%(>G5AB*+6*
@r3686
TTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAG
+
>;-5F?0!+D%;H#264*4E&DE,0:/?<4A24A86*=@3">+9-(&0F%'A*723?3H6>F#$='/FE5=7A#5
@r3687
GTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAG
+
7:@.%#/@%C2(:$+H@=))*D3/"9%3*#2C**G.0CD'*F"9+*63CH$C
@r3688
CGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCNCA
+
."C;6G*-7$2+'7A:2@C7H/%E.+/<D%$60+1"#?2>9#0''?:4-@A;#>/<4?
@r3689
GCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTTCAGTCTGCATCTACATCATCGAGATAGNTGTCGTCATAGGACTCAGCGGTCAGTTCG
+
7!2,C;--58.2D1<(5.?DG,3G<.<"2/6,GC8*,%:<+1$&4F@4#%38(0E7,@#FC@B:&98AEDA4-F5&:D2&0GA<E@8%3!7H7*B,=)">174#'A)
@r3690
CGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTC
+
(C:><1<85!?0-'94&='"<2#6*<5DF3&,A'EE9678=F?+G6;04)<5H8;9+>$)E4&*E(C?D:2A,F"8$4#/G6>)!B:-$:/2=<C:<GE5#@$2319
@r3691
CCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGG
+
;C-<"2@FB;32A%>:('8:45"@<7)(">&5&*47H>8;6G!'2*.,HGG"#0CE'>$:.A2*#<=+)>698?&?:-6):=!A3GDA:&7E=<=1.-)3B8A(!'B
@r3692
ATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTGATGTTCGTAAAA
+
@DA$:HB%C=!1@4)#&C2++1-)H)/%D%>/D&)#(D./$)2?1&6/)"0!,F''?(:H%>
@r3693
AAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTNGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGT
+
#>/B9<3#1:@2"1504)%B9.38$5H23@%D3.87&H/9>>G>%'#"F:*<DBA$BC:$(3C!*%A4)0$'))0A9@E:+:-HC0<&<A$5/2@2HG#53-.<G6E)@DB
@r3694
AAACAATTAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCNGCGTCAGACATCNNATGCAGATACTCACCTGCATCCTGAACCCATTGANCTCCAACCCNGTAATAGNGATGCGTAATGA
+
'*&")(!%%+&)+(%%'&*'&$!'$!(*!'%")$$(+*#(*#%%+%!!%*))$#$*)(+'*()!'&&&%$&*&#$%"$(*")#)+#!"+#$!('+(''"(#'+#%++!%&'%$+*'$(&)#$#"#%%(##%!(%$)&#*'("')'!)"!!"%!+'!%*+(&!%$!%*&!$(+%$'*!($%*#$$#%)!#+$%&)*&$#)'+#''*+#)!&&""&*&#&)!&*$*'+"%%)%%*$#$*
@r3695
CTCATCTTCTGCGAAAACTTGACCTTTCTCTCCAATATTGCAGCCGCGGCACGATGGAA
+
A'=74>.DD801#7&DF(GD?%>C7870?B"H'427);+4+&:.$5?CD5>(%)7/.CC
@r3696
GTNGCGCTGCTTNTNCTCTATANAGTAGGCATAAACACCCAGCANCATTTTGGAATAACCGACACGGGCAGACTNCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCAT
+
'*$*'*(+&')(!'(""&$&%("*+&&)$''*''(+#*'#%&'*"&+&%%%+'($'$'%+'$#+"&!&&&$"$'+#)#'%+$&+*%&"+$"!'(&)('"%+&##)&((#"(((%'+*$%'
@r3697
GGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCAT
+
G,-G69E6?1)2?>?3@94.%.,$H'CH;828#+=7E8;!@)B;/?B6D%-DGF.<H+2<=0F--2G@E"72F72'*$AE+<=5>./C7"5;-E9.
@r3698
CGGNGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGNTGATTGAGTCTCTTTGGTCATTCGCCCT
+
8>FD0)*;$;D;B?139HG,7/))2!:0<."5BA(,H67F%><E>9.6*A=+"45"&160C8/C4)D1'H>F#/H*"/069'2E0<4)$2;??,%+:<==828&>GG=!"G*H(.3,$%*-(2=G3D.#)<=1".=#
@r3699
CGCTCGTGCTGTATTGTCTCNGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTA
+
*&!()+%'#$&!*!%"%)&$"$$$+)"*(''!*!%#+'"%#)!)%#"'*$*$(!*'"!&&!)*'##"%%"%
@r3700
NTCTTTNAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTC
+
!=F$>$D"<>*.%(@$2)E<(EE,-G&%5D*G,/?!)294F!+1?&+/A-$>1D
@r3701
CGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTT
+
C+1D>:C:;8D&B:'3H@C97(B.=B<G+<*5.08-.?0"#9(A=1G!$,00"H:0=D9')H?$-19E#9B37=<><::=,,2HF0<E<?/A;.2A9=)%3-.FD(+*-%$H$492C<@DF*%*?+A,A/
@r3702
CNTTAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAANTTCTGGTCAGACTCTGAATACCGANTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTA
+
'!""")%+$)+)('"(#(*)+$("(%""*$"$(!)'&&&)#&+*"("+*!)*"!*$+('$"()'("+%!#'#*%%)%''%+)!$+)+%*(&#(#'("*%*+##+#!!)'#"%$'!%'$*(*!%'*+$!$$")$#&&*&("'$)!**$%)($+#
@r3703
TTTTGTCATTTATGNAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACG
+
=<;:*0.0!H*>)9)@):&6>2$)4E#(1!(.2&C7-8*+8(E9'7+8525!;E&!$3)"G*8%;2E7$'FC>/5;0E99!6#;=.!6
@r3704
TTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGNCTGCNAAGCAGTGGCTGAAACAGT
+
/:E':E=$4+!1"BDB'42F);:580@/+;;$F9)):-+6%AC)+<!78/55@F17!66H7067<F'!:0.2A3225):@-/:+%39=C5'FEB;=/:&!+9$G?5&)*0*%-<'B"@@F<53%$/>0FF?E6:'$FB.2&596#%.B#5-,7BE3%GG702*!8*B*A9=D,5>#+F#+-)<>3>(#4=+*?"3#3$H
@r3705
GCAGAAAAAGACCTGGGCGGCTGAAGACNATCTTCGCGGGAACTGGA
+
#6*8&:1425@*3#&+A,!$G%;.3-+)>9>=3&;1>&!0.'E;HC/
@r3706
TNNNNTCGCGGTACGGTCAGNAAATACGTTGATGATAAAGACGGGAAAATGCACGCC
+
*$#!#+'*&(#"+*)#+&'&)"%)((&"%&!)"%$)'#%)$"'""")$)($*%+"$!
@r3707
GCTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTACACNAAATACTGTGATGACCNTTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCANAGCCNGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACA
+
##'++$'$!"$+%%*(%*%)#)*"(")'&$!(('#+##%*!&%+*$"+(%($$%*&+"'#!+!!!*!(++*+'**"++)+)!)%&!*"+&$%%()*%'%#*("(!*+'"++"!!$+#")+&%&'"+()%+$"%))!((&*!($%"$!('&#$$%%($')%))#+&"('#*()#+)$%+'*($!"&*''$*"+&+*('$&!&$+&')*
@r3708
ACGCAGAAACAGCGGATCAAACTNAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGA
+
6&'CH":D(5G89>F=@@,(3+!!/%G4!586?45>!)1<:)>>,(%%<#<D0?F=B89%,!0:-5F1")CG(%)'&0&CF&=4&"F1/1C!<9%68(1%%B#&/C298&%:",.4-$#!1845"F.,!<F!GE<.=EEH);#<
@r3709
CCCTNTCNTATTNNATNTCNGCNAATCGAGNNGGCCCTACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTNCTGAGATTAACNTAGTAGTCAATGCNTTCACCTNAGGAAAAAAACATTTCAGGGAGTTGNCTGAATTTTTTATCTATNAAGGAATAAGTCCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGC
+
*")'!)$#*%$&!"!"!%($%%#$')')*"!+)(%&)%'%)'!)#)%"%*"'!+(+$+'#)")%%"#"+&#"''&!'$#!"!'%%+(%*'%(%$(('%!$#%!$'("*("(!+*!)"&#"%%%(*(##"('%+&')$'*&*%'&)()(&&&*")+$$$#)()'"!***&'++)#"&+'"'%%'%#+$)*%"'%!%!'%"(!(###+*'#+*+&#")%+'%%#&*!(#'(*"!+&'(%
@r3710
TTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAG
+
($#*&6&::2*6&!>=,#774D.:<7$/"2-BB/5B#G*,*>$99C7DD%*8C
@r3711
TACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATTGCCG
+
D!534=1;@!<*-D%C2)!''E"%EFCC"61D@$,#)?42#;>
@r3712
ATNNGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTC
+
#%'+#*#!!(&+)%$""'#!#')'"&#$&**%#!'%(#$!(+*#'$*&*('#""$*+#($+)!$)$&+$#%##)&)#$$$*$%#+#)"$!'$#%!!*+
@r3713
NCTNTNTACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCC
+
%*$#)$&))++"%+)"'*!%#)(!+"*%*!$')&#%(%+"!)$#!((!
@r3714
TATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGG
+
-'(.8H#(C:<B#H%<,"6/=!'8/!=51CG;94%AD57%%D*3"6.%%-H9";>E8.(0880+&%6%)8;(/?C:,+><68)@87/6"C6C7%C4>'C6,FE>&H%"3B8:.=
@r3715
GAGAAGAAACGANGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGNATTAAACAAGCN
+
+=%%88?5;&F")@89<B"*00;..D13EA5(*.05"!1D8,.7G/)5&494>3@:*@;3C$&C<F?9F391B?10A7=:-@@@9C8HEDC581'$
@r3716
NAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGG
+
(0;!G6ADCH2*+9D!#;G??5*G@<"<<&7(.'"E"!+30F$8-0&=#
@r3717
AGTCAGGCTGGCGGCATCANTTTCCGCAAAATACGGNAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCG
+
D--.H%;=#$#?$AH(@"6'562#:F(D"D+89$:+H!B3#6&A%5#CC2575*3':FAA!47G"&E.4)7@2>+0=)=,"":/"9$6?%.;E-;09H:%:%"*@&2%$(
@r3718
ACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCG
+
5D>,F<ABGD''>B6$/@:5.!*0+.!$G&A'-$AHG0!,G<!:
@r3719
NNATANNCTNNCANNNNCGNNCNNNNNNNANNTAGTTCACTN
+
!"$"""#$#"$$""!#!#$!!!!"!#!#"#!!$#!#"##!"$
@r3720
TGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATNTCATTAAGCAGTGGAGAGCGCGTTCAGATA
+
DCA7<%5264.3.(E-%F5#2($%4G1#G7&<C&5C%;'72<!4D8&42""C4HG&34';25:6$/A3!=,%?<::=D6$=+7A&
@r3721
GACCCGCGTATGAANCGTGAAGGCCTGCATTATGTNGTGATTGAGCGGGATGAAAAGTACATGGC
+
27F#HD%-63C&=C8')H9'0@1$H065-7:$H)A>//%.(+#&"G8A;B6-6;,0)3'B?;0?+
@r3722
GTCTGCAANAGGCTGCCAGCGATCCGATGGTGNACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGNCTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAG
+
8=88?6(D#'HD(*-1789<2&9-/>#9+%D3,;D&,??238A:D!F(A2&>&)"72>6%93*7(/?8G79A3C*!0>,+(=#':5&"$0?G'==G;35D;E;.5C0#.(.HBB='EF$<:?G).(./%@@0BD.)4%45=52*<98>:C3EGD1D;DF2*@B"D
@r3723
ACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGNCCNGTCCGTGCAGGTTGAGCTGGATACAGAGGCTG
+
C%*8=-<73%=?$;E0F)''728:C?9FB650$406/C9F"8"%6+:1?C;1A%4+FE*)EH:'0?'5$%CD*G:"
@r3724
TNCCCTGGGGTTCGCCGCGTCGAAAAAGANCAGCACAGTGATGACC
+
/#*=H"GBC$:.6*"F:&H.B"676"1->F;BG0';(>$C?>*1&7
@r3725
NGGCTTNATATTCTGTGTNCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGANAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAATAAGCCAGACAGCAGTTTCCGGNTAAAAACGTCGATGACACTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCA
+
'*#+#""%'&&%##*")!#&!%(%+((%(")(**%)(*")($"#"(&"$&"!!&&"&"#"##((*+$#*&(*"%+!#!$$&####(&%*$*)#**'%*!'*&**$$(%''%&("'*()("!!("")!$$&*&)!')$!$!$$)%+)##'(*%(+"#!++")$&+(*#*)$#$&"!&)#*'#&"$(%!#+#!!")$*(&'#"%##*+&#$#(!%'$)
@r3726
NNGCATATTCTGCATTAAAAAATCNACGCAAAAAATCGGAC
+
(&2%=<B.=+#$2B=1!=E7H6/4F,:)?8+!A'?C(,#$@
@r3727
AAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCATCGGNGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACNGTCATACCGGGGGTTTCTGCCAGCACGCGTGC
+
@#9;@;BF&;7C47</3E8*!51C-)H26)68(@;3H+/65.'0>$1C92?3B'-,(%DH980=;;>//#-%5<#(5=-"?3A'(4?@$6B?@*B;:9")@7!,>E2@;D%-<-<%8;-7&@8!&0?D%(0!1CF.+A%3E?>4&399A(3<-,(+/D**EE/(7#F%;!7E&=7'*235DB!7/50'69'"(G"=..@C@)B-D'/H>'5#:$,"=+/3!H
@r3728
GTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGA
+
&7=%727?00H>!=6<.:$,7C")+:.#,&1#28#:%,.$<(?#@DA-.('@,)%C44/.:F34+0/::1G>=71$1='7*5G<(C,7C#B-A</=B7(H
@r3729
AGCGTCTGTTCATCNTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTC
+
+E*5$$:'>>DDE';86:8/@-9A90/4E(!3E0E$2E5A4!?09E$H(D?(*-?.5ED8(6
@r3730
CCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGA
+
;D"*E$;<$!E4("=@,64%"GE3H>?)/"C2B?,<A$=/3#.5.-"?99.A(H%3"/)%,5(HGF27B>4F%B5
@r3731
TGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAA
+
6&<!61:6HD%-8@26)5@)72-H$=3!C69'7A.01:>8'.;$C&>;2,/A?'(&
@r3732
TCCGGATATTGAGACATTCGGTGAGANCTTAGGTGNTTTAACTCGTGAGGAGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTAATNTCGCAGTCCGATTTGATTCAGA
+
6E9=0;760;FE22"9>);D4(,DH!7&(6,#'&EE-=7;8(5<06E)'$10>GH3G/$&+5E!+716H0"8H1:,?G86DH7;:FH1GG!-/<)**/:,1(4:#?D02"<9DC87
@r3733
TCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTT
+
G?D#G;@$&!",-H;8=<B!2-E<9;;$@A8<&%+)"%H&*4
@r3734
TNTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGT
+
#&8@F*=B$,2HC+8+'613G0-G./56H@'8@'77D/"-C8G@8'/:81$%'
@r3735
TNAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGNTTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGC
+
",F+4$AB<;G-,B3EC45F7>%36!EE8$275/5A>(?@$6$1+?)F2E-H!A')19@.!')0CGD-H7-)+'B<)*.<+B*5&F#(.22.%,0E+B++H<(#=22H,11/:F=<4CHF)5C+7%;E/3@@3=B601F82.H%-<-4/9B,:'1CD892:47@1'7)<B*+F!75@3@F@$0F-"9.+04/
@r3736
TGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGT
+
&*+")''+)*#('%)!$)#%$"&#*'*)''+!+%&#*&+#)!%#(&$''""$+!#+*(!'+%$'#$+!%(+#!#)'*'%!&&#&"'%$$#$$+%!)!**
@r3737
TTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGG
+
>C-?77@:D7):596%>C6E&FCH?D?9?A"EG/&D(5-9H*.1.7G"1
@r3738
CATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTAT
+
*'4F@=$6A3*E+:5F2H1$77=5(4'F8787CC*@;9-$*.D&">46@F2>171%@*,?.//G7*"3"#+(AF!=*:2-E03*$+*<#:0?(*F=E;-/7E<140!:
@r3739
AAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAANGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTNGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTNGTGATGAAAACTGTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGNAGAGTTAAGACGTAA
+
:/AE:G39DC).(B1G4A8+&4;/*0=2=1="D>99?H$"84':!(A/8D8G$G3,>*A5E*,,!.1>#/,A$*'+5*4+.'%46F%3=6@'5;.B%G)9+$9619'2-*@5)EA29$-CF60%;2:C/78%/1%,,%7*1$:&H:-833,9;F##?2.$H=B%?HD!!>+?""'01$7F;&@6$/6H2:20/>=EG=64:*'!#<0""D).4$(/7*>$>H;<>87,>H$>&'/CF$.@G26/@)(=72-3H%!+*+(*>68(7@,75#'$%26A@><,220)8H<:5&(979-%,E)4%5B:0=3A/E+&!HH)355;0EF-1";G,0:/1$@<!?3%*B
@r3740
GGGAAAGAAGACTTAAANATTTATCGCACTTGCTCAAATNCNGCATTGATACATATTTTGACCCTGAATTAT
+
+)#%+&'*%'"(*%"$!)"$)&""#($(('+"')+"("%!#""(%%'*&'((&"&%"&$))!*+$!%"")*%
@r3741
GCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCNGGCCCTTTCCTTTANCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGG
+
=/F#4<";D2C.%6-3(8+C2G)DB*H*99)*07@37!?AD'H<0:"AF"5@27%)/+@@>.A#9>F/47@$'<4,46;>F=#9$.)
@r3742
NTCTNNANCNCNGCACCGTAATTANTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGCGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCAAGTAGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGG
+
%')"#$$&++&"!&%&)(+&$(#*!+&&*$)))!)!*'%")+(!&##(!$&'"'+!)+%"%('"$#&%$*+"$"')(&$*(&)&'))"!$&'')$&!($"!$%)'*!%(&(+&&+#%#%)**&&"&)#(*"*(+)'))(+"!*))#%)+%+()')("%#)$(#(!&$&
@r3743
AGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACGTG
+
.::5:5A!(>%0C*&F")(EF4DB3-F+,D';,.<(<*A(,9E!!3+,F5"$.=C/":5.C21D;27DG
@r3744
CANCNNCGTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCANCAGCGACGGAATATCACGANTAGTCGGCTCAACGTGGGTTTTCATAAAGNTCTCGGCATCACCNTCCGTCGGCAACCAANTAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGACGGCCCGC
+
(%#*##")"+(%+#"*!'"'")&(")($(*!#*)()#%&&"&$#+((!##!''*!#+%("&!)+'#"'$%)%!+"#$+)'%%"()%&&+%!%'"$%"%%$+#'&%$$(%$)(#!'$"!'*&$$(++&&$"!!)(!**'**$%!"#))+)*)!'%+#*"+%)#*)&+(")$++*+"'%#'%)!$#!!#&))"&+)%(&')*)!*%)*)'!++#$$%$%))(#(&'$$+#$!!""(%*+*&(++&*%$+!')(**(#+"$"&(!*'&&#%)%"%"%%!!*'+$(!*#!+!#$+"&"''&'!%++))&$&$!!(&*'&+&&"*#(()%')'$'$)!'*!#''!$#$&($
@r3745
CATATACCGGCCNGTCCGTGCAGGTTGTGCTGGATACCNAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCAC
+
<914054>(@-2A?FF60H0"2!#AD&/")-9%@,D/G?B:'7#:9,3<&&D8)!=FF/(4C=8%B@H8&B0D):--G150#-@,E?,.1A4#36-@9B18)9)@>
@r3746
ANATTTGATAGNCTGGCGTAACCATCATCGAGATCTGCCNCATTACG
+
("++$$**!)"%'(!$(!$)(+)'*#)*"($)"&$#'+)*!')(+*&
@r3747
CTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTT
+
.7&-8"A1/E4,+6%?0;3&'H26DG$#./DD"/:C2'G04#@5*2)5+6#@6
@r3748
TATCGGCAGCGCCATTGGCGGGGCTGTTGGNGGCGGCGCATCCG
+
>:(*78%*C*3F0=@;7&2=DE!E9B%''.22F$:5/HD%-4"1
@r3749
TTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCA
+
G?6"C4;5!7-8B)3B%<5F#<:-5B/&5/G"'4EH945?#3
@r3750
GGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAGTACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGAT
+
>CB7C)D#18)>>>G0@'B+/+:*)8,).858,A21D,0-&+G?G,:;*-*::.;>/E0:(76$:9$DH3'FF4G*4""(@H6!'7<)4F%+H3;C6@+F9$")8#:>2%;0)<,*A$67;9+
@r3751
AGGCGTTTCCGTTCTTCTTCGTCATGACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGC
+
A'#C?4*"/<;2E3DF4A+7(EC5=(;91)F-(#+;%0DA(/0,D51=/"7<H@/HC)4(%2?D>8AB.)#)&)<5$EHH=C/)-&$?@&50HBF+*0."G(.C19C70'C4"()D7%F5(#")F(4'30:F(=%FB.2)%9*>A+*'+*)/98*D3,%/"H/
@r3752
GGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTC
+
>6:98",(<0!**C<$?;F&9,.F.8D=FG2&)<72;'/*,E?
@r3753
TTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCTTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATC
+
?A749E%779="GB)711%=*/'#=/1+F;F8%0=?3:.5>#*;H&H:/>#CH7&-+;6:C+#0)>F.H/@,&0&89=3<,-@'H??.>,+3B-#H4/F!E8*2D=B8(-2'7)<)D!F%H,=$@#-9"5&E,D:3H
@r3754
GGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTG
+
-$D%FA26HF2*D<5,D7;@0;0/.)06&5B;3CE+>EA@F&"(2149-.6<&67'C''!F432*<
@r3755
CGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTTTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTCATGCCACAGGGNCATAGTCACCAGAAACGCGCCGGTTCTGATGGCTTCTTCCACAGTAAACTTC
+
;BBA9CE1DC,@*:(0>?%;FB+13H8F*1;!E5%>%7-3*,C&5A42AB#7G2;;5A&5;6+B5B4$:/F.<G'5;+3?G(F)/+-:CDE*@(D&EH?<%("#'97G7)F853+9B/>8%%61GAG+8'6;%+##G)0@F8<3%,*E=50:DD%6C)/3+9@=</<.+;1DG+**.:4&/&(1=E$!3422#+5D75DC40,@!8)54#<76<2"*,8.DA3=$!G#/%>A16E7<=C=!H*%5H3%H/?#>"@A<;7)%<%HD%:30.'GE9"@#!5
@r3756
CAGCACCNGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCNGACG
+
BC$@/5DDF(>63$*9,>@5/*!$0:F3410517G*:9EFB/>&*,
@r3757
TGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGTTTAGTTAGTATATTGAAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGNGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATG
+
1,218#"36@B33H@59E>4F:*1E.19'F$E8A#GB(-<9H'.CA'.3"=B<A.')>:!1)(?@8';'AA(<E+AH)/:.36AE-*43@5<EDE9@#?G#C2CB*,:2"21>!C+8*3(2%E?G%69;%5;C4?D'D%=6F,&F@*%:FC.F&C(=C1"B5:8-B<!9,>G(GH
@r3758
NATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGANTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGAC
+
,:%2!#$D%?%8'"?7!?<.+!,G,(!81G?)"%,+>.+G%8?,)"@+71(@1@=@D>G!&*=61*65F!1;8@80@#GF"*(F;A:-A;BGAE:'*110D.@-5@?=;1%C14'1D53%H=G?"7<"*B+H0*G-#-1#G>4%4CE4:<H*E;.00G'-+
@r3759
GCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGANCGTGAAAACGGCCCGCCGCAT
+
H2/!8CB4G%D6,?465"2F@%F4?*9G':.:$2&=@@5:8=0FF-<;0=3=B203)8+(7@:G4"D<>A53G?7&;2->5A@)38-;40'$3$B/%6)G;!H3460@=;>:E/?F2.8G/$F"0$@<G@!E,6=;G8BH?9.308E#"2BH%E4@.-
@r3760
TGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAA
+
&AAED($$;"3:)1>F?*";=*14:@%;#)154F.F5G*C!!-*66+-G'G=01A51-+A->8+6('1)@>!&8C//;9/C-%,"F1("8%<(B93&7H+:$?F),7&66-=;*#D'337=1F90<EF=1<"D"!##
@r3761
TGCAAACNCGTNCNNGATGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCT
+
%#("")&!)&$!*%!'+)$#*)"$#&%$'''$"%"#()&)**+%#)!'&'*%!)*(()(&(
@r3762
TTTTCAAGTGAAACCGGGTACATTGCCGTCGTGGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAAGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTGCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGG
+
H296DG6#HE5,+1C03;4CF93<>H<HH')-,=>49=<(6<'&773.FD'!)65$C)C<0(1@'8D5&;*'4A%**!$,$'08/$@A2924)4373>862,#/3;*%3'-=C+G;:A+$@.?;+F4@5(004HF>1*7?E=-+4:>$?6#?%?D$-B,+/&'5=+83F)6?C53/'B9)F<?@C.BG)$F+52(140+7?'$-5--"/;E-EE/0*GEC-/-$;(=<*G
@r3763
GCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAAT
+
90!82.#BE&-C(H-@E<39"2F'2&>0;DB<83@,H004+)0)=&:%/"
@r3764
NGTNNNGNCTNNTTNCGTTGNTTNCTANNNNGNNNTCTCGGANNNATANACGACGTNTNCNGNANTATN
+
""#"""""###$!!#$$"!$"##"#$!!!""!#"!"#$#"""!!#$$$$"#!"$$!!$"##$"$$$#"!
@r3765
AAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGG
+
9@3-@5+(='#(7G*=8;84#"(/+?%07GD;02""1516HF992G@A@@#;H/1:2H0"%!-6)(%';,<:$*8)D:%
@r3766
CTGAACTGTCAGCCCTGCAGCGCATTGAGCNTCTCGCCCTGA
+
>!2?/>B?!+3??E8%8)?*122B?+C%C,!:>@$.$:E#//
@r3767
AAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATAC
+
+8D:#==*&5".@8;2G85.#,AEC:<#>/;$*C>=C9=;-H&:C562<:A2,'1(E*54&+/)(C=6C'."E4,-'02E32.;3%A?H9:$-%+,9E)A'05:)D#HF473&"G
@r3768
AAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGT
+
G,;5G.:-/#-:EC;F=88-)9'5%1=33!@7G=4CF%/%32)#;)B?8<#.2CH/38G<,23!+F3-6@H.3@+='7#+-#6@9C+53D#
@r3769
TGTCACCGCAANTGCGGCAAAGACAGCCGGCAATACACACATTAC
+
,8>G!>#@)4;-C%(#B7.>-DADC'7@EGCE:4B@=485&9")0
@r3770
GAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACNGAATGGATGGATGAATGCCGCCGCGA
+
F4!F>)E>9:;H**<D?!C:';*5=?F1H&,#+33E13?4H"0/)(2G#8'<)>5:"&BEF)@<##E3/!A@</:2CH.89!.
@r3771
CGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTNTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCANCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACG
+
E$-30=C+C&D1*5.,<9@67H.45;E#+B6.;.)",-B24./*(*E8/>05%B1G19E9$/!>7!>406"3&@!B+(-A->,H26&0E1;$)<!G0)77>2,A64B9&,9,-C/E)!')>(4$';8"E9D"736%-514!H@E<7FE%4?*HAB<*5,!)-FB5#H-,"<CB##+B6,82"F:1,G:'<6D&GDDD6&#&>521G=.E6#$EB$(32,3D&G
@r3772
NCNNACNNTAAGCGACTGACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTAATTCCNCAGTAGTACTGCAAGAGGNTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTNTCCGTCCGGATATTTAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTNTTTTTACTT
+
"'!"&#((#'%*)&))"%+($(!&+*+&(+'((#&#(#$)%*&!($#)%(*$"#!#'+&%&(&++'$)))+!!#!**#)"&"%($*')$*$$*$)!&&'#)#$&')"*"(*##!*)%#%&*+!))#+#$))*'#'%%""#)++(!!!+(*)++"#)#%**+'&*!$#%%++&'%**'(#'"()#&!'+)&$$+*"#(&"
@r3773
ACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCTATTGGCGGGGCTGTTGGTG
+
2"D>2+3,FC""65E/%6FG'C.==3'9/.63<C/G0B0;>C4%,0?<H7F5/%93@<'4G=$1FD%'.'0>9-!>C00CF*5<:B,H2H(37H1#2C;=.A%'6&H4#E@83)
@r3774
GNTTCTTNTTGTTCGCCATCCTGGGAANACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTGGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTTCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAATGTNAGATGATGACCGTACTCAAACATAGGGTTGAGTATT
+
5=?..'D0).()7F>.0<'&HB*G9D3%;,.DFF'$E?=6C?H96/'-('?G-$639!44A";D+=@B>,&7&F7(28?/1&5-CA1D/-@=0<6D)."+62G(@5A=#$'DE"A>8(7'6D"G*4>.%F=*37(<9%/7*?'@=,"903;*34B#)@/'-6F5$F9@27"6&+?(</H9>22C6""6F60G'C4:D?EE74EH.,2F?>03B/6A:@!>E*A58)0$+G$*D;D,7?,;F7>+#1$//6,",<GCA'%9)93F:=@?%C57$A!(<:!H"26*?%,7)*#;9,)*@7H=EAB;8,EAA,F/F>AD,'.8D29*?G'<F)<"/>
@r3775
ANCNNNACANGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGT
+
$*(&$!'*!"9H#8>H4.>;!CA"2+)>$.&@%?/#;0FD+8@+"<B='./H<<":CB/<9CC>315>&H0!4HB(7)?4>&<"8B15*.A25>-@<;=C>"0(@G/!@@-39A(,<34.=EF=%),4<!)5-E@>.A
@r3776
TTGCTNGNNCACAGTAATTACCGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGA
+
$&&)'#$)"(*&++$$%"%$+'"*'*#!!"(&%+*(*))))))$)!(+%("%+!()!"+&%'*'&&!*%&+)'##&"%)(#+"!)'
@r3777
NANNCATGAGGCCGGAGATATTTTAACAGAACATTATCTATCANAAAAAGGCCATCTCTCAGCTCCTCTGAACAAGGTCACCAATGNTGAGATAGCTGAAGAGATGGAATATTGCTACGCAAGAAT
+
!''#&''#%#+)(##)'((%+'(!&(#+%&$!#$$*'%"%!*!)!!&$*&+%')$(''$")&"*)*##*&$)((&+!+$+)(*$%)"&"($%+*$#&&+!'('*#')$)"'!(&!"$!%&*$(#)#
@r3778
TCTTGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGNCAT
+
*$'+$$"%*$%$'!!%&%+!&*+)!&'+'((#!$#$$(+)#*(+$%(+"%$%"#'#+%#('!#(*#&)!*%*"$%'*"%+"%+(*#(%+!)*%'&"%"($
@r3779
TGACGACAGCGATCTCGATGATGAAGATGCAGACTGGACT
+
F60EH<C2@?%2+.+#!@&8D4,5(">D=.2@5)>(6B74
@r3780
ATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGAT
+
>2%9;F+)*$!-&C,*G"5<&'64H.F:<:@C(4CH8G$F3EH3!%F<E!773#
@r3781
TTTGCTNCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCNCGGCGATAGGTCCAGGTGCNGGTGTTGGCCAGCAT
+
0A67!53B?04(1-94<+D40*:>C?>DCG-"1?&B8"EH!E%&81/?"H';E<9G#=6F<0":/1,,F=$-$!,F,"GAFD5C8F@/:0?A,A3DB5G><?'C1(;*1=+3H7:1CAB"
@r3782
CATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTNCCGAAAAGC
+
4<7;<-(6!,9)/28&6@$3.&AB&""98=G5"&G45<$C?&#/!7H-(1,
@r3783
NCATNNTNTCGTNANNNAANNGNAAATCTNTANCTANNNGNCGNNCNGNANTNCTNGNANTNANNNCCGNACGNNTNNCNGNGCGNNANGAGNCCNGNGCCNCANNNTNTNNTTNGGTAT
+
!$$#!"!$#!"$"$$!""""#"!###$$$!"#!##!!"#####""""#"!"$$"#"""$!#!#"$!!#!!"$"#"#""$!!"""#$!#"##"!$##$#$$!"!##!$!!$#$!"$$!"!#
@r3784
GGCCACTTCCGTGTCTGACCTGAAAAAACATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACG
+
*+=)-<+?=C6C3+1.2H)2A81::<F@6D8;!445'B8)1$CC!!?G'"FA31?0>7*=F'+6&$$G4=6>
@r3785
TGCCCAGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCNCGACGATGAACAGACGCTGCTGCGTG
+
'%$&)+'%*"*$)%#%+!##!#(+&*"'")!&"+!$&'*$*("#"%(''+!"#(')+%#(##$'(*$$&("%&*%%"$(
@r3786
TCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCC
+
>/;3"8D3H@<?+50E"%GD'6+:73FC%2B,&818?8D6(F+/A4&@:--*7(0D:%<!F?@*H/
@r3787
GAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACC
+
@>*-D$%G78>B#:(7#?:)(!36;25+09+':3*/)'?)AGE9"$/;08%(2+9%2($D?402#&
@r3788
CCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATTGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCNTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGNCGTTTCATTCCCGTTTGCCGGGTCAATAAATG
+
-=FG*#"#E=G-5>6+).+@"'!#7.H-1%=<*G8,('4A%.2(C#/)?12A@F1<:4892=6773;@%=,>A/$=?G:(@";>&BC?=);'+%$"D&)@7G$A1$4"41!49-<F<7;E9G1$>G43?;#C<80A:12D+2./AF.-.2H&@%$,=5A=H-CE+GD8,+8&:(
@r3789
ACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTCGGTCAATCACCTT
+
1&.$A)D>*";G1):,;923,("6-6=B0!B/<8.B0;!F<>4@&(=G0!8."9$0;'/%13C3;&!?&H'F
@r3790
TGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAG
+
/8D-<9FDD>C'9&3A@=,/H$&")9:*+1FFC;!035*&:>E/EEH0A<19D0>*9@><A3,+F$06+3"A
@r3791
AAGANTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTT
+
*'*%"'"*#"$#$%(#+#!*)+%#%(+$)#&'"#!))+"!'))'%"!)!%%$++&+#&%%
@r3792
TCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTNTGCAAAATCTAATTTAATATATTGAT
+
5/:;G(E-D->?HD2EE)87*:,<B,4:8H;E>01/1$!4;5C6$)":7/AB)**(&'=9<5/7=-&>2?$&/+<+(/'9H+1AHE@>=<C2
@r3793
ACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTNAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATGGTTCATCCCGCGTGGCGTNAAGTGCANCAGTATGCAGCTTCACCAGTGCCACGACCGT
+
=730A%/"77:'3;,&B+>A(>#-E#?28E2"""E&=E8>)-1*."9H93./#80?-*/),19.H#%=++7/"":@%)H"+#D!=%609*-=&5:66.%H'3A*)#&37B'!=1*-&%.*F'D/A:8H'>/55&(@5B5-FA,'5'1'03DAA$.B#1*)>5,1()A+G%;$3@F?@6-9="+,.)(D*484E8>+3!G/'$
@r3794
TTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGNACTTTACTGATG
+
!435A"4=>BDF9"1+=HF!9/!8)CE(DH1&G*10(>/3H)45$!D*!7?!8
@r3795
CAGNNCNCACCNACNGGTGCTGCTNCNTGGNCNNTCNTNATCGCAGATT
+
*()!"**"*&(%'(%%#')(&&!%#*$(&!(!#"''*%"*)*#+%"('*
@r3796
GAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCNCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAG
+
/74C!--+H;F2C%?$'233HAE,4)-,14/#:539;;!5.&!&)8'65=E)6G#>28-7/<@.0C45"./"*F6#82E73,4<,F2/:<4-&$.E*,%)G07)@D*3:+
@r3797
CTATCTGATGCAATTTTCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTAGTGCCGCGACG
+
@<7,:03#7D>(@:'*AH5/A.D-@?-#7!,4:CFG(H@0"'G%(H#C7/=+.+HH2/+:)!3#37ED#DG93)C7#.9>2+--&+3<D@'6*:+@+5.C;&?;1?HB.$2&H46#8!=6,&&(@;F@E($+#9<G
@r3798
TCACAGGGGAATGGAATGGAGAGNCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACT
+
%',)%(3A040?7?>4&046)&0G,#)D&.)17''('1-*C!$;707F9"8!B"-+F+30'67%#FD5)D.1<'E
@r3799
GNNNTCAGTNNAATGCCNANNNATTANGNTNNTGNNNCGNNACTAGCCCTCNNNCNN
+
#!#"!###!$##$""!$!$"""#$!#$$"$!"""#!!###"$"!#$$!$!#"$"!#$
@r3800
CTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATC
+
9C0."BG64/*H=ED$-4F0*0(3)6>1$),FAE4:9@'.C1"/-C"B2
@r3801
NTGCTCTGCTTATAGCAATTTCAAGCGACTNAAATGCATATGGTGTTGTGTGTGA
+
!A=0HFGH18*<6-,<<29H#$+@,,1,)!'$*5.;2=>@"D7B"$013;$G6H.
@r3802
AAAACAGCCCTCCTCATATAAAAANTATTCGTTCACTTCCGATAAGCGTCG
+
A!!BH8GB)FD7B@DGG2F8;G8-D2-2,!/H',.,=$60HH@"-!"&GFH
@r3803
GCCGTCACTGCATAAACCATCGGGAGAGCGGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGT
+
,*+=F33"-+7+:-G14.,/"&%D2G>/>!'142C:$3@*#32$''/6@<B.0A-EB/$3!F'=*%*'#C2G6#'$1<);H>*<-2:7G$B:"?-$;?''83:!G1-#,*GH-400%C1E/1HH:#2,<3
@r3804
NNGGNNNNTTTTCNTTCNAAGNGTNNNNNNCNNTNGTGANNNNNNNTNTNCTNNNCNN
+
"!!!$#"$$$"$$"$"!#$#!"#$"$!"##$$#$!!##$!!""!#!$!$$!$!!"#!!
@r3805
TCCGGTATTCGCTTCATTCAGCACAACGGAAAGAGCACTGGCTANCCAGGCTCGACGACTCTTCACGATTATCGACTCAATGNTCTT
+
;<C?>H'D+5(2*?&B846?&:)=6536%%$9&B=DDE':DE1*7+<=@0HB0C#%-;$655*;*CD"9?'#3%D(9)3D?A!>!E7
@r3806
NGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCNGGCTTGGACTGGGTGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGNGGGATGTATGGC
+
!+'#%)'*$!('&')"*%*"+"(%(((&"""'&*!&$%*(+&&$+"#++('&)+%')&)#""!%*""'%%(*"(*"*'$&!$+)())!")($***#'
@r3807
AGGACTTTNCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGACTTGCAATTAT
+
1C!,',)ED?%C3"5)&DE5.65@6D($6)C7;<4D-!6;'B-&4A2A#**0E2#;)+A&),D$:
@r3808
CGAACCCCAGGGAAGCCTTCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGNTAATCCCTTTCAGATGACTCAC
+
E4/?E1$2-E>;$A:CD@04-1'9/<)9C02FE3"51?7<0E+.'%!5!91G@&H>=9<9"0"-HE>E"'>*6.*H6:EA"G
@r3809
GCATCAATAGAAATTGAAATCGACCATNACGTAATGACANAGGAAAAACTTCACCAGATTAATNATTTCTGGTCAGACTCTGAATACCGACNCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTTTGCTTATAGCAATTTCAAGCGACTTAAATGC
+
7%=9E7'7?32E6#%';!/67<+3+?=6E/<0+3,+-H7@@?54;F&+$BCB+#E')$%D475/*37078C;%H@CBE0A(,F'"4!#@B%@.D*?A)%/6+:E<1)2+A-<">&#*H.B,7C8@+80#HE%#7+7H.#?G4<)D3A)%90<7.5:F5?<B:$G@)4&/-B&/3)25<;
@r3810
NGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGG
+
$%913.C)E#C5BB.5*%%5?=H-@B$*610=F5GDC,?*=HED$(<C"@:#+
@r3811
AGAGGTAAAATAGTCAACACGCACGGNGTTAGTTATTTATCCNTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGTACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCT
+
:@;E?>=/D(/E()0A<E17(3$A5#C$"#:D&!)=2E!!$H&FE)>3$/EFFC?AF51"2%CD';A)$;=!B=B*6;,&#C-4#'5=##E,+9!&F?7>1:5A#1=+$-D9-(8D52><;%./-3*7+*@7<:@28#+!%<"28.0(@*8?/"#,-%
@r3812
TAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCT
+
/6/D,$<G$$*,F<;:!<>($'364F4$$E<6"F/@/E<+<?87.,-8,H,F=D
@r3813
TGATCGGGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGANGGCTGAGCAGNAGACTCAACAGGACNAAAATGCGCAGCAGCAGAGCGATACCGAAGC
+
:74H<B/$H:>&4'1+-B@H'>6@DB.FE<#1D0BEB)$F7#?#0B2G@*>-$#1E8(<0:=7!GG/G3?/!+.#42(7!HB+.$7=#:@6HF)-07*?C@#
@r3814
TAGAGCCGCAGACACGTCGTATGCAGGAACGTGCNGCGGCTGGCNGGTGAACTTCC
+
E'<%.5/9?7D3<>=#77$9@45A0.97$C??E6!!+3,6827:@=6:7AE>!A+=
@r3815
TAAGTTGATGCAGATCAATTAATANGCAATATACCTGCGT
+
6>+%H,-+=#:5&#5!@<.A2C+'16.9-<#'$-($0,!%
@r3816
TGTATGCAAATGGTTCATCCCGCGTGGCGTGAAGTGCATCAGNATGCAGCTTCACC
+
),<F=4'*'%G<;8@2**D,/*/:)$B.G%;834-+C9=@&"2)('*6(518<8$C
@r3817
GGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAATCTTAAGATNCGAAAACTC
+
50'3A@GH*:0:(8694%#/!'?F(HG?C"-6;'(#47(D/HH;-"9GF:14=G-C-H4=7<G"3-?.;@.+D*@68!(7E6*D*35'!%-@#)1&.,'E<6C10D2>%%??(7"F5"9=
@r3818
TTGGGTCANAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAA
+
%'#"&%)!!+'*#'***##%$+$!*#)(!$%"$*'#()#!)"!&&)*!)#!"+'*#'"&%&*##!+'!!$"&$+&+'&!$&)"'!+%!*$'!!#
@r3819
TNTGGCGGTGCAATATCGGNACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGNT
+
)!(*%*+$'&!+%$(('')*%+#!'$#"&$+)()(*!%''&'%#"'!#))*(!))$%$%!&+&&(&###()#"'%*)""+#%"!+**'&+'*))+#+')*&)'+*+$#$$#+'+#$$!&')#*
@r3820
GCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCNGCATCCCTTTCACAAAAGCTG
+
68%'C0#:??$;:8)%=:0;.%9,0E3;/E@$8F!H$3F$,<F(/1C##'64:C!/@B'B?@*52(G>(3,&?>F?:.$?F*"E-()$75262?":A8=
@r3821
GAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCA
+
<-CDG9(;>%<+8D?'!>64"@;H41+4F-;E@DF$0$E/(1E?<'+:"%0A!F/$8766(>20#:0G#A*=/,8)$G(+3;3.HD?5-D=$A<-1E(*-D'3;#CHHDE?$7DC3?-!D@%&7.)9,-E6&6C"<1"&!<0G)696=@CB&1=;<*4A?3*3./5#=#!6
@r3822
NCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTGGACTCATTGGATATAGTCATNAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCANTTTTCAGACATTAGCCTGCG
+
#@2A5=F"G4(G7G-%"%*&)5%@;4+50$.:>-1*4:1B+A)BGH38.?:&5F139FGF>$G5%D?56-**-*C+*>>)!=08GA79;H9;3:)DHA84)-GH@F)**:BGC=8</$#8;DF0H1A<+0@5#H!?A$=,>&2'47=$DH&29#5!H58A9$/C9-=@>1;0C$:
@r3823
TCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTA
+
=A.//&=1#2?A,?-A'<<.6?DCDE):7A%)A16#!5C<<
@r3824
TNGCCATTTGCTCCTGGTTTCCACGNACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGTCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAA
+
'%%")&+((")$'"%!&)#%)&(+"*#*$(%)$$'"($+$'+&)&*#")#"!$(!##)$(&!!!*$&++!!&!)*(!(!%)(%')(!&)!(+'!&!)&)($$%)")#)%"*
@r3825
GTTCACAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGANGGTAATTTCTGCAACCGCAGCAAACTCACCATTACNGGATACAACCGGAATGTTGACCTTGCATGNAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGCCACGGTCATGCTGGTTGCCGCTGTTACCGA
+
(&(&(!+"!$)%!)$''&$'%$%"**$*%%+%)(#!#!*&+#!"##&&'!'%%$!'&#'$+&*#"&$!$*)*))("%&+##"%*&+*%(&#"$)!*&+!**&'&!*)%+#))##*")++%!&''(!%#+(+&'*'&"!))($(()+')((!!&"(+#+"**"%+*+&!*&+!#!%&)+*+$'&'*"'#)'"()*$)*!*("!('#!%*$*%$*(+"&#'*'$+(%#$&%"%)+%*%&*'+!('%&(+"%+)&%&!!!'")$)#!&)+%*&*%&($#$'&+*+*')$))(%)!!$''#(+&$+$)'(+&&%&"$))*'%"')*"!*!('($%'##""+#)$("*)+$
@r3826
AAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATC
+
546C3!)'..AF"7)%:=94?481"&9<@21H4?;<AHB1G0
@r3827
GTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGG
+
95?5B2/,$@-0=A'%.E"B=&(B9'93:=0.:D1;'44*
@r3828
TCACGCANTCCNNNNGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGNCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCNAAGCCGTCAAG
+
)&"$"&'!%#***!"$+('#!)!))*$&'%(#''#$)#)&+#%*)!)#$'#$%('(!'*!%*($$%"&")&**)!)&%*%%!)#%'!)$$("++'"#+#**!)+'!"(&"##*%%+#$+'"&%!&)+$)'("')+'+'&++$%#!''##%'*#!'##*)$%
@r3829
TAAGTCGCGGTCTCTTTCTCTGATGAAGGNGTTTANGNCTTGTTGGGCTTGTTT
+
7</38HF6GF85!!03+&.1+,A)>:/72:E51D$#14C#7!0(99,$B;?B)4
@r3830
GNNTCTTGNCGATATAGGGATGAANCGCTTGGTGNACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATA
+
"$$!*))*'+%(#&!)+*)+'%(#"#%%+**$$!+("''')$$*(&!%&&%++""*)'('#&%%)&&"&(')%!
@r3831
NCTGAAAGACTTCTCTCCGAAAAGTNAGGACGCTGTGGCATTGCCGCAGATTAAGGAGCGTGGCGC
+
))'$*'(*!&&+$%&)!!&!+!'+*)&!%#(!!&$%%"*+'$#&&'!(!#$#(%+(#+#")&)%!)
@r3832
GTTGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGNGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGGCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATA
+
?E%/-HF<F*(#?;$-"CC(>./;895:)(C>038F'55&C"5FDE/=**95;G8=8H671-8E@*0?%//4A/8-=AG#%#9:8?52G=!9G)C6!E%B&4+7035!3/:13&:"8-%4HE4A!!AHA:44G#6E.?<.=GG'/H-,=4.!9DH3&/3D1*6<1?">287;*#(G*H)7G6,;
@r3833
AATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGANTNTTTGGCCTCTGTCGTTTCCTTTCTCTGTT
+
:<3BC/A)@;&4,1A0!:)"/??)4$G-+0G=AG"H7#3+7!73*:F"*+6",.G$$4!,/1<,8B@&AA9;@2.,E:E=;=)D>"-.+C,*
@r3834
AAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGNT
+
<515(&<6#6:?"+*6;$*,F!H8@B,E:$&0BBF8)%BFA@3;3'/47,+8:#?>A5(C4E,!+='4*)!6%(*%%>7D&FF!(/=.721-/@+/3&()H3$)F:"++3EH>!9H**H?54-<H7B=6--32449%$D+:*>:A,A1)*37EF42EGA$569%H@5H*A@0%&0"%,A2C7384/+D.0%7=/<!017E-'@.&6C-&&9?7.AE=$;)$84)1$#(>'*1.7"0%,=7.-</HB!:6(28A.028/3
@r3835
ATCGGACAGGGTTAAGTTGCCCTCATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCC
+
-=H>8=>?;6<<A9!505#F%4*@**B$/:">85>"A+A$H8/=)%-83ED3FD*:C(:.E!-.)52),::/.$;%
@r3836
GCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGNATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGNTTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCNCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGGCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTNGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGA
+
:6(B+>5G4F;)!BG=)=(?;*F@G:18&A744CE0(,,#:/F$36-)==;&%?=D:FB/=A1AFE2"G?"%F'5F"0$*/@>!=?A@(3".C<-";#H7#60D1"2("=;?DB=*>1$15@)*@2?F,<H&E7<8E*-7'/7+-'166?7#D@4E80$B5>%3.F">(1!58#'>F0&,GD8)@AF1&2C37:7,-=%?<"8&"E'891$8&37&)0G=#*+$DE741>(!6@D=*&7!7!.9)B4/<.:0)5(,A+$0=7(6C-#=0(8*6,,(D//?D2+!9+8??/DE&<BH0#C;<!G*;&716$39<+D:9D.F-#>E3>>59+$/+8%)0$0A,H%.FD'?874>?+@$BB8CB*/@G<G>.63.D1?"<6#6$2!E>)1,6'2'&C4=1$14$*5"$G+C+'G5%B@7%:H7>6!(&#E<0;.<"!D1#@8!2!94"7.1E'))/)"*1B:AD&:*"$
@r3837
AGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTNGCTCCGAGTCCACCTG
+
('366*8G:2A2H%+G8(A(0E+A*C639EA<2-E(6'<;2:,"<?2&AE@8)+%?E>6B+4AFF=.F749;::61D>>@)11CB@>)A!&(G<=@/$6#FC-1)',(<0AE7)F=@*2>B&B!9'#=H&632H<*93!1B(,E*H8H$!B*37A<@EH"><)!2,4?-CC);!E3F:=B#,D):?B)D-,0F;4@=2/0/G0B@
@r3838
GGAACACGTCTTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCA
+
)CD"7;*(,@?!1#+:%+&A:<F5'1#H:2&6>,<H#.04;#@92+C6-+@966F.
@r3839
CGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATNTACTTTTCATCCCGCTCAATCACGACATAATNCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGT
+
#$7#4</@&0##/E20A!A"A63<'1=2.2?=%#'$&)!FH?7+;>A><B49=9A8=6*7/+(?D==&+'@/9!%3-+@F(F.B;A<0*3B284?D0"!)',D=3'!AHC;.$+3C-'H>6"''96@59H":$A5)4801*EF>"(A:D>1>>5(<
@r3840
CCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACG
+
;H%-(/-@>:8:<7<>GD/CD;!:#(@&84!G"&2=-E>(?E=33?6&G+A%0!&7D$H/BA>47.0(9(F5E,174@-+'/:,FA'95<5<+B9325<-D6<E:+2-:51E?%8,
@r3841
TGCNNNNCNCTGCNGNANNNANTCTCGNANGNGNGANTTNANCNGTATAGGNNTNNGNNANNGNCGNNTCCTTTNAGNNGANCTTACCTGNNTNGNNNANTTTTANNGNCNNANGNGNNNGCCNCNNNNNGAGCGTANTTTCNNCNNGGCNNTNNNAGNGTNNNACGNAATTAGCGNGNTACNGCTNNNAGNTAAAANNATGTNNNNANNNNCGCAANNCANNNACANAANNCNCNNCGANNNGCNCNATNAAAANTNGCACNCNGTACTNGNATANNCAACACGGN
+
""##!#$!!#$"$""!$!$$#$""###"!""#""#$!#!#$$#$!#"#!$!!#$$!"!$!!##"!$##$"##"#!!$$$"##"!$""$!"""""$#$#$#!#$#$!!"##$!"!!!$"#$##$#$$!!!##"$$$$!!"#!#"!$!!$$!#"$""!$!""$#""!!!!!"""$""$!"!#"!!!###!$$#""##$$"#$"!$#$!$$#!!!!$$$!"!##$#"#!#!"#!#"$"##$##$$"$$"!"#$!##$"#!!!#"$!!$#$"!#$"!$!$#""#$$$!!$"
@r3842
GGCATCCTGCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTA
+
$++!'#)%+'+'!%*)**)"*")'**#+)&&&#$!!)()*#'+$'$
@r3843
CTGCTGAGGTGTCATTGAACAAGTCCCATGTCNGCAAGCATAAGCACACNGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTG
+
'(0!82'.6A=*!-'AC9@5$#?F'-;G)'E1%"6"5*"E!B"!@A8+'E)#7!00D6+6&6'?8B270)E.B:EC0C(&=>=:B44H"<%@:"='.7-2B7'329E@A2'H*<
@r3844
GATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACNT
+
>'!-<@C8;@A*/582?:-&+B)E@FB0-8FEF?A+A%#.;7"F9<D
@r3845
NNACTGTTTCACATCGATGATTTCAGTGTAAGACGTCCAGAGCGTTTTGTTC
+
!"DB@;D!6"46<&$..@8+<=>F)11486FC>28!#&8%=!C8(:&$2%H2
@r3846
ACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCAC
+
&3HG;"=6+6.25E?(5?D'2C;B1/.G?A%+--6*:"BHE1<<H12=.)3#A,>-643C$HH#EF1.@=?'E>6&59F!<2'<0D5C1&D"F(5H*'7G??(-(=&%#-HG0;E$3,?%,"BA
@r3847
CCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACANCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGATG
+
+$+&+!%*'(*+!#)$'+!"(&*"*!!)'($$#)+#'"!$"%*#')+)&%!'((*("!'('$'&*%""$(&)%!#"+&+&++#*&*$"!)&+
@r3848
TCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAA
+
@0)B""E!'"%#261=9$G;.3"A*8*489F!$9%H6*;/36@87B<.!('')9;,ADEC113?G.6CB%H;:-:?89&8>=8!!A3)68&&)4:D8"/0,?#7;.23)4*/$B="<H26*)4=7:&46%AG7E1/+B"D+0(?7:3
@r3849
GTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGCAGTCATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGNCCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGNAAANCTGGCTGATTGACCGGCAGATNATTATGGGCCGCCACGACGATGAACAGACGCT
+
+'##(&(")#!$%+"*&#++++"*+&*+)!%!$*"$!#)"*')('"$))""!(!($'$(*"$&""*)(*+&%#&'#"%+##(*%&$*$#"&!')*#(&)*+'#*!$!&*"))"+*$'$")+'&%)%')%((*#%)((*("+&$"'"(#(%'&()!$#($&%$%%&!"*%'*"$(!+*%!%%*+%)$#'%'%!***%+$"%&())!**#**!"$$$###(!'$*"!''&"&#)(!#($%*+$+!"&(#*%+(%'&#(
@r3850
NATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCNGTGAGAATTCGGCC
+
)DF+B(40E&077++)*!;/FF4%&9!):*7<",.>+"#)EG-(F'/A/B;A)2F<1,;/E#34
@r3851
GNGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAANGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCNCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCGTTATTCAGCGCC
+
%!+)#$$(&')%+!!!("!')&%+$'%'&"*%$)'&("!&*#&&($*+&++"!!$'(&$%"&"#!%$'!%#*+''')*%+!&'%**%!'%**#**$)#)*"""!##("*+$#&((''"$(")%&"%*%+#&'%*)&&+%%))$'(*#)!%+*!("%)!$"&+')#"$#%!&!*"!%*##(*!!+!$%%&""'**(#'*!*
@r3852
TTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCC
+
>+;!E#A!;*#"8#-CE096-28'D=B"..B":>"2.5AH5C#)6%!);%217DB2%194??#A+2?C6=9+?0:!FH&B&,.%G38#%-";+$4;)#4B1,9#$.%?,:2745D6(3>G4.8F/&1:5A6D&,4%C%94D3H+
@r3853
GGNGTTNACCNATGNGTNANNATTANCAAAGCCCANANAANNTNNTCNTATCCTTTNTNTAATTTATTACTATTTACTGAGAGCTTTCAGAACACTACACAAATCTTTCCAC
+
'&!!(%!"#("))")"("*#$#)"(*%!'()%!%)(&%*&###!$'"#))%!(#'%!"$$&&'(!+())"*"%&)!&*%++(#*&#*))#%!+%&'&%')&')"&#&*(''#
@r3854
TTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAGCAGAAGATGCTTTGTGCATACAGCCCCTCGNTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTA
+
.(FAA/18(C,<-/A%H300?:-<"(%8H+)3:8@-H,&+.7#@=9<;$35!9=;D++$E<E*.4:(FHH*):8CHA0>8<G<?8//76%#+#;>F)/=51(GDB5B?;0CB>A&=?$"!</*1D'A/%EH.&:2?4AFGE<:@H*;A,'0G7@@:#BA;-C;4-E5E.(38"24>$3#+,G4G*AG58$A)=9"0HGG3/"*?/:+0$>"0:?'A3G)':9'0@:@H;"!#!(.*D*(2E.#,EF-2:EE363+1*B3-#+A/100:%,))!#3(A*/?8=H!%.(>1!'-)<52;1.'225;+E?++70#$=-G=6>;"G>)>(+#FED6>2>"CC%-=!:,+6G/E"/0*%1-(3<+G5-&*!&!3(F"H*??9;(:8-00%9AH@%/1'&%CE?6=0??A?%!"G)(9<4$H6F34,@D@#0>+%2
@r3855
NGGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATNTGAGTCTGGATGCGGCCAAATTTGACGAGCAGATGGCCATAGTCAGGCGTCATTTTTCTGGTACGGAAAGTCNTGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGGTNGGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGG
+
#$+)'#*!+*'#'$*"#+#!)!##!&!$*%&"%!+)(+'*""$'&+)#&%'#&)$('+#"#(()%'&+#*&$)+(%'!#!*$!*#+$*))#!+)!!"+&#&$"+$$#&*#"&(%#*()#"$#$)#'#(%'"&#&++$#*(!!*%(!$+'$()'+"'!##'("'%""+'!$""#+"('#&+$!)#"!+!))$"!%'*&'!$)")"*"%#))&"#
@r3856
ATGCAGGAGATTAACACTCTGCTGNTCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAA
+
H'):6+!'@$&2#'7:,8.%E%4GH<4B"GG3A"$$*858<18(/CHA71:8<A!7/#86)4+=:14&35<"<0@@84G*9A1%G0;'BB'H<:A#')!>456E!+57
@r3857
ACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAAC
+
E0A,%#94'4(.;4"<B3)*1:$-4":5A9H8)2($#=25:$&C!?.=G%?;4C//.+,"<(<;812,7H79D.4?-470#D3@)5;425H'?)7B6@A;(1!:7HC)4'F*#;2=7<<'+$5)8)<04"2*8*&H$B(HGD6-=0C&!7/'A<;'.1)E*%9#=@'D
@r3858
TACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCG
+
&,)B3<%.C?2F(6/?9@'=>BEE.0/)>10-DC3+G@4)967#-
@r3859
GAGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCNGTAATGAGCAGA
+
&#89F&1B/&3.6.++,:8GB0HC!0@0:?G32F.G.0"G'C;:1C+04;54?<''!!@/EF$,?C3>BC3:=&=.>"@$A*#(58%
@r3860
CGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTT
+
6C>$)>+H9CH.1+9,D(G?.<5-:25>+):!27$0.82.!<C!84$0
@r3861
TGTGTGCTTATGCTTGCCGACATGGGACTTGTTCATTGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATG
+
C!CDH01D:+)1>6?*D.G"=.3)$D1+2D"C?6DC1+/>=#><!/+H7>5"*&/F1B!+F!=H.$70H%&E'-7=5,'3+%@$6@*2>DC0F2E71)2129@@(3:E.-%15*<3=5$56E1(8F$1B=(:*@F))G?'&%3HH?,$:<)04BB%"4D5+:1ED2B6;6DFCE?/H.9+'4!,7;
@r3862
TCTCACTACCACAACGAGCNAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATA
+
2-$C3@;5:6;!&&G5!?A@=+6',$E,?/<F!D(0=<0>97;!)3+6/(-E"AB6C9C:0='5D1%$=!F2=>6+')4324;D"E:#8>).H"
@r3863
CNGTTATGGCGGAAAGGTATGCATGCTGGGTGTNGGGAAGTCGTGAAAGAAAAGACGTCNGCTGCGTCGTTTGACATCAC
+
%!,!#,$0D#4<2E'+.26B-,G<6C7<77'6+-?9#,#A$7+.=H:>,+:"E.&A%*388=/B'<@5BB:*.7A#40E,
@r3864
CAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCA
+
?C):2/0&C!&A#0&E4@0/7/DA5&<@D0>E79-+2A%+'"!%,)!6E<)0
@r3865
GATNNTCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTTAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCA
+
(%&''+'("%"%%#!(&*#(""'!)&(*++*&!#++*#%'#&("*)%)("&((&%')%%(#*#!!#+##*$')#((#+'$'+"!*#)'(*%!&()**'%%+&")$*)))+#++)$+#"+(+*%)+)($(++(*
@r3866
GCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCC
+
FH23GG(A(8H'&D"BH-FGDB/=57:E5&A'5&F"'D01.1B7'6->A:06)&=&3G"@#"<8:50?@!>.?40:
@r3867
GGNGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTAAGGTTGG
+
(*!#&+##&!&(*+"&"%*''+(#$+**'"'!'()"'%%%%*+&%&!#+%)*!(&*"*&*%'()+!)(#&+(!'&+)&%%!+%$*)!%(%
@r3868
GCAACATANTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAG
+
'.>-#G%.DA@2D>+#B<F>+$!&E&+,48*<&!!F>4?!::<<40B%
@r3869
GTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCATCCG
+
,1E+9H/3E;5$+@'@2*,G+.2.@!.$&EE$5"94$F97;(,$5.:!:6(31;)'8
@r3870
TTCGGGAGGGAAGCTGCATGACNCGATGTTATCGGTGCGGTGAATGCAAAGAAG
+
4""*AGB0@53&7>4H:E/DG-3-A$/?B-!39%-'"%.+26'$G0##,:;>*C
@r3871
GCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATT
+
%2/":&&E$D@:*39A=="F$,70)-&9!6GF5/25G*2<:(,B$+*,")CH,15':-5#=<)>/-=)3H,../DG;8B@AD#==(EC;E+22&
@r3872
CGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGTTTAAGGGAAGTTCATCTGCTTTATGG
+
(55"#33:''C./&!+@*#D/0";=783<21=/8;9-'+;=;2%1#2'!.=0F:6&:!)0E:&AG*?.<H@(;G++F"(?@$-!/&;1-H<0E>6
@r3873
GGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTNTCCCGCGAGGTTGAAGCGGCA
+
'+$))&(&()'!!#"+*&(()**)++*$+(#+$')%+"+'($""++)+%$*#!"+$&!&*%)"+$$')'#+$")"("*#+$+*"*$'!)"!#!!$+
@r3874
AACCGTNCCNGNCCGTCACTCAGCGCACTGGTTAAGGCGGGGGAAAGNGGTGAGGCTCAGATTGCGTCCATCAGCCAGNGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCGGGGCTGACGGCNATGGCTCGC
+
*(%)%"!(#%$#''%#)&+))(**!(!#"($)!'')"***"%!!+%'%'+$%#%++(%*($&)#)+'&%$!$$$+)$'(*#%$%!)*%)"*%#"(+('%+"$($%'#'!*#''$)"!)#'))!*'")#*$'(''***$(+%$*'&#'&($*$%+*''"+(&(+&!#"#+%(&&("!#+#$!
@r3875
TTATGTACCGAAGAAGAATGTCGCTGGACGGTATCGCGTANATGTATTCAGAAAATGATTATCAAGCCCTGTATCACGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTT
+
2"0E"8G#6EG@(=%=+&2>C(H;<>&%*FH(/+@.'=.*1=2&8)758>#<3?++=#'$?D+F>,5)/F$E2A>>>6&-H0D@-A>?H0$*5:+&GFE8G#+9=$")A058)&H@C;#-A/('9-+23.%D#,(9,A*C7#)15CHH6
@r3876
AAACATGACCTGTTGGCCGCCATTCNCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGNTTGCAATGGCGTACNNTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACT
+
$H>)H=0(H"12$&(,301072/9?,7H!9A=',%<;EHB&3*!3E;;2%3<,5D0&2@,!'//5@C"HE:3)9-8?(!;9-.;;A-(A2B5"H?'+,3FE+%8:"=-@2:':#%<9/@(2489F.9H8<%*G.=1F0=H,&0C#-A90)9/"+=9$0;=:.9C*F,/D.(;1A;"1(5&&'!@&
@r3877
AAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTG
+
=&,C#;;:B;=G8@B(B9"*>9#$&:6&04%'&G>8(+"!.?3:).@;5#&:.;*A,>:*3)#D80%=):)F93A446H=&5BB'-+A&6;68A./6
@r3878
TATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTNGATG
+
G"-/9>E17A<G7+D=?<0>17428H361@7H5-9:A=--.8*7;'E@77'
@r3879
CCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCCGCACTTTTTTCCG
+
"+%#!)*#!(#)'&&+''$%*"$(&$+'#%#*()!$*#"$((*&'%+*%)'!%++%())'%+%$$+!"%$%$&'+'"##&))$((&&'+)*%%#&+&)$')*$&%)
@r3880
CTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATG
+
B/1=6@8-63,(B*8&07@A.#>*F6'HGD?1'E!D?".4294E?>-CA06+<%AG"?(B-*!D9C>!H?+73G8&-A(5E$,"@;
@r3881
ATCTGNACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGNTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGNACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCGTGGCCACACCTTCCCGAATCATCATGGCAAACGTGCGTTTTCGCTCAAC
+
+/@.'F08-;:%7&8$-+=8G3D(/G24>G':*!/'8((F0*!.H084.>;(&"BC<<"9:?C!:/@G2*;E6$D70!!<.,=%?1D-4"F=9=*.7"4$&#.<8?F#;B)$,(##(;05+(=61!/4D0E>0:3!G!-AC#!+2;2G*=+65'H-@*#A+'0:B>"0=FAD83(/"?&7'?=)B4CC%9@)0=F3,#?5E8(
@r3882
CATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGNTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCNGAAANTCCGCCTCATCTAAAACAGCGGGGCG
+
E9E1&/:.HE-C"*9*$;C3A:(@*CC6(%@:F))-#"+'";0A;.!!197DFHE'1(44!4BEF6:0.F=2&&4C=@H,,>%.-!@">8!>67.1,B+9E+2F5-.7%9#A0.0#="C/&C!<,-!(F!$$B>.BD05F3.?#15;.5:*0!(>00;A"*H256D7E.DC*;;::$>:7=-?GC2>'?37%%0H0;;(0E8;E#0&B)$6)3E45-17B6C%$-?E6<.<@&B@6B?C#1,/2&,9-B=AB.;8&>'-.(9
@r3883
TTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCNTCCAAATGATTTAAT
+
E3($1F3A92/8F92D5.F>H&98E!9%32@-,:$&'0G6E<!1F;E*,,G#A(,7!
@r3884
CCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATG
+
<3&,:"+6+7H6.BC8H+$3=!*=2A</4>!13*+E<15"05B</<:.</<@37>66
@r3885
CGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGANATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGA
+
8*,0-:2(D3*-7HAB,6,2#8:@!8D7DH)!"-"&,E+5C8*+"'?F'5#.9$5/':3!>8)**<7B?)@B.1C+/E-=
@r3886
NTTCTGCGNTCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGNAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGC
+
$.+%/%"F+.>&&,G=<#G>D3G20'=>;@1;(<F5H,9;!5$!8>)C*AH/3"*%#-)*4D/(3)$#-%$!"1$<B3=&%D>."-+=9,,:HA&%("0>>.F/7)/;3/$&:;4A-@0#>2!"G<!4,5G&D7F&+70@,3&D:G%93=8)D@F$7?@.F&C>#D48G#D<D7?8D")%-&+5G:->:!4H!70)!>7E+5"-!28$<E@F#&C+.?/(+E,-";;HG,)E'BDE(:#60(7:8HF$EF$0
@r3887
TTTATTNTTTGCAGGGGGGCNTNGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTT
+
04-;G9$,6/D(66#2DF+B@>B:/,H86+>1&4F'GA8(A-,$C>D(%*8>CH0%/&"?&#;0831?!D=,/#G'51+
@r3888
NNCGTTGACGACGACATGGCTCGATTGGCGCGANAAGTTGCTGCGATTCTNACCAATAAAAAACGCGCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTTTGAGGTCATTACTGGATCCATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAG
+
"$4);EG&8HF$0F(,D)=F17GB;&?#7/,?<0B16(-B')+:<%,9:6?=AE.<.;4/8=32%,,0=E#=..AG0'&-/G%-1H:96'9A@0G=D3E36!%>1B@-B=6-5-619-6%7,H86EGD?5H-D,%7?/6C0*3?4'7(8$'G(@.(!)-='76@,)@D.=3+;&-.1<$!1&1>$#(A>G9-/!-#*&&=
@r3889
TATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAANAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGA
+
*2;$2("3E8+==A!!02%((F2@2@526?1"B-B$#>?39+H54(9>&>$3-F,H21#;-13?)@%665'(CA-1@%.88('><5!!3@E4
@r3890
GCGTGTTTCTTGNGAATTTAACATTTACAACCTTTTTAAGNCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGNATATTATCTGTGGCTAGAT
+
2&3A0)+*>0!,;(=%H.!@&6C(7:11*52$C;><!9!015.-4/($7.FC7B27A3.DA'7!%*9(C/',&*C6+3.1C;G6=&<G*8)D?''A<,0*&&
@r3891
AACACCGTTACCCCATTGATGTGGTGAANATCCCGATGGCGGTG
+
)(#+)&*""(#$)+)*+)"&%&&'"&"#"+!"+&!$!*(#%'$'
@r3892
GNGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGNCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTTAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAANGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGNCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTNCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACANGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCG
+
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
@r3893
GCTCAANATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGG
+
1!)@88'*=14+:(<'C#G<A'&D/DD!9)GA"3;;'@8!7HH?79<%!33)B%2)D>/3!'E%B!-AG?#B>G
@r3894
ACCATTAAGGGCAAAACCACTTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGNTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCT
+
G6,FEE+9*9#6"&;<:?D$"%'DG:*+.07<95,-AF<?H)%"A7)8?)C=60%"<F+@>,@A31/%/&8FG4=A*#*G/',H+?"%A@>*29A=&>*)6B(G2C@G8'*);/88C!%
@r3895
GATATCCGCCTGAGGCGTGAACGTGTCGGACGTAACCACCGCGAN
+
..'9=%'#8@A()B(#A8(E??+:97)"@)=87*5@%()9<:2+3
@r3896
CCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGG
+
)+ED%5787<4<2A&1;7%C5%694/#)/2?)6/3)E)4B?/
@r3897
CCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGANATTTTTGATCTG
+
4+>%'2$3D06>>$C1<B!)!:F7@2"#/>-EC<0,<D#H7E%%8.H70=?@!+C!F;?+$F,.:+D;3?H*&9".6,H&0>==(196BG;15!B$F8??">8C0:.>?DB;@BA?@69#"&%''8%0)$+=A:G&!B%;310B.4*$HD?4:0F%H>9$-"5G2@(+">*9H++GA*:!/(BD;C-8B*%$&#:3-/7)+-=:B0AD,97(/*BB9)-#"B4.C%@A*(,G'&0((D&A#FG-+4E'
@r3898
AATNCTNTAANNNCCNNTCNNCNAATCAAAANANNGCTGNNTNCNGTNCANNGNNTTTGTCANCAANNANNA
+
$$!!$""""$!"!$"#"#$!!#$"$$#$$##"$!!!#!$#!!##"!######!!#$$$!"!#!#"!!#"$!#
@r3899
TAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGG
+
9,HH2-@-""%=&-'/>53DD78H.(.G<>%B9A'3;G)4)-2=+#4.5H-'@2?#
@r3900
AGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACG
+
CE&$9?B2?6$C,3?>@D8=6>6$#A7)!?#B(<>$3<>C5GC))72%#4F:H.+</F$.ADG%?!.C=&0>>3@%G<C26E7?%?F/8/!3G-.<2@158;?
@r3901
CAAATTGCAGCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGAT
+
7:&'@<;,?F@E;*5746=7*@##35HG"6A:)*;B%;A/9>-+17&2+C-<)>?2B-9.?,H6'-$*>"+A503E4%=>+2!7+B$!C%>CF3B
@r3902
NAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAA
+
$06#@#*4,:3;:=.3FG9(>H5-213FB*>6:-C$@;6*5:+-;>BB9.0#;AD2/$68@"D''(<F!('C4$@/:%9D:06#D?=;G/+).
@r3903
GTCCACACTGCTNTCACGCTGGCNCNGAAAAGCCGCGCTCGCCGCCTTTACAATGT
+
5$>?13D(+>;G?6/&+''14EC6G/3@G(!'<#"69!%=4C*<H@$6!'(+=B<9
@r3904
NNNNCNNCCGNCATGGCNTTCCNCTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTA
+
"!#&)#&&&"''''+*'$$++%+(%!%''!&!')$''')"$+'$*(*#*#**&'$!'#+++)$)+&*&##$%*$*+'"
@r3905
TGCCCGGCCGGATGTGCTGCGTCGTCTTGAACTGATGGNGGNAGAGGTGGCGCGNAACGCGTCCGTGGTGGCACNGAGTACGGCAGNC
+
;3;&2:(G#&))3;9.!G(4$:E"HC##F:!8F:":EGHF(3-'&5A4B,#;C*EC4;E+F*G1!E?(;CF!2/+AE!H*0*:B#G9/
@r3906
GAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGNCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGNATCAGGCAGACCCCTCCTTATTG
+
-,BH-EE36#4@:9,4E,H;5F@BHA2/H?E).<82"/<)75G%>66?%#$>6E818B<?/>:4@49D-H;<)0@4<,DB@=)#0/0,:->:&%F3.D6(<BED4H2&&$B.!G-0?)E5%$7"0'">B+1!'+54#
@r3907
ATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTT
+
A!03)0A-?9E#!/'B%F(>8";G??)"("@>,.;/2F$/1(/")"$$</.C=-=D!-BB@*>%3C@6#9D,2;;%#!B+:-"1B>;*#!<?3=*<:)+5205,#
@r3908
GCNAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGAT
+
(&#A$#=2'#%H5.)>#49.G1?G:57+-0!5@$F#3F;+6)*"F00A>&.4+1<H6E%,DH0)=,>8*?:%<3G@E(%6$-16%6'@#;!=,6>+8.<
@r3909
GAGTTTTATGACTAACAAACCATGGGAAAGAAGACTTAAAGATT
+
B<C/=#7:G0-$.6<)7FD')$3>1,DF9H3/;06'DH/+"5A>
@r3910
TATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGA
+
)/%59#+85/6?,"2H,4&4*'@5-#3($A(+85)D27,0>G7;6A(2=-5&)F9'+C/30!#,.!>6%&%1'G5>$%'?6'@$%!??50+>*)(GD:
@r3911
GGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATANCGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACT
+
C=B:)%%.!B-?2"E@D>!??;"2'5@/G&@9,)$4.'";+(>+9*-=+4),C#@;#=CCC83%C9A@*7E-1</)!8"H,8FABAG*4&111-G@:*>!E)4993!H5+/78A"<#H'H:DF:515C;DA#B2A#F:G'8#->,B<,14H1=(<@"+94E#%$C1DA7)/:/"6771>-/"*=64>/C(25C3D';3+?A:C&7@!>/F8H(3B<&1,?
@r3912
GGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATTAATGGGCGCTGTATGTCATCGG
+
&+'!*'%'*"$!(%!+#+'%*'$$#&**'*$"&"%%##!&$)&$**+&+'*(#"*"#'"++%!*"'!!!#($%&%%%&+$((++(#*&%+(%&'"%(((
@r3913
ATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTAT
+
0/#408$=-AGAH"7*F@%+8A8E&*)CA5;2)2:#9A6,>
@r3914
CAACATATGCANTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATNTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCC
+
%=H5&*9-'>90C&E2/5!2E=/E-5!)07H"+@$>(5%%-8H1G:5'7%BG0=E3AE&BH"%&FB2BHE/@E433F<5GF)E)<;A@7+;?@G24=E(D57!!46&.?>)->HC:),-.=54+&9##3G%,,5D-:9!1);A)-!;EA-$(=;><E')+E378*E&F(04@8%'5.D#!4.B)$2"$<(=048%(8D=G9'G9E12G%%H?FG+<C3)/8282+5+@CB<GHH&*-!,5@#$%AH29A.
@r3915
CTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTG
+
4'FA'B)<$?(FEC(#'D0%$$2:;,*C%<@-28@5/0,B>>G&=G4.?'AD,$&C%-01D'2(-946'708'A+C/#
@r3916
NANGTGCNGNANNGGACCANNANTCNCGNATNNANGNCNTTNATGNGNTNAANGTAGNANNGGCNNGACACGACAGCNNTG
+
!"$!$"$"$!"$#"#$$""""#!!##$!#!"""$!!!$!#"!$$$"#$$$$#!$#""$!!###"##$##$#$""$!$##"!
@r3917
ANGNTGCANAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTG
+
&"$))(*)&+&%)'+%")#&$$$#+##"'#(+"%&"("#))!"!')&$(*&)+($&!*"%)#"!
@r3918
TGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGC
+
@5@:4/"EE"1A'3FA,4FF5EC'G%G5%GA<?B!%E;;7$E.&/3A$E9:?34>@A'"9CA+4);+:9)<:>EC.8.C;":F/7:@$%"8%FG!;-27(69/
@r3919
CCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAAC
+
)@#@607=-<5/(C$5D/32B33(@+2!%2*$$3E6,>!243-*!-AC1.7H)8')"(1
@r3920
CCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAGTCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTC
+
"C#HG4'/7;%1E&*2+585A;.*:0)':/==4D-AD;!F-A5!9EH?==0%HE!FE$!4<28>G?4#%.$!@23/0A0!F,<>G56+D450B3.%C61$3C7>2C&1H@F,A*<*:*2B19/#9?3!,@03>&-2='=AC5-;;"#G2&6)@/-.5,42!0<?02-F".?**!9&'%(+0@1)<(2(.5:H-;64H>*26-4BF+5)*03=:3):"+C82>FE&6$*',;=24HB"#2?8:771>,FG$+H%=)>%#>!2F*E22(=(G7#.9@=4)%39;@*@>8FC=D68>5C-EA4E#AB).(#=1#;D)D.8BC,.(6'6!?@B%+00)G5F!!02B3@211,;33/)%<3,D17D'%A2!,4"%D2!645)#BH<1%51"10%/60>"E4
@r3921
CGNTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGATCAGCTTGAGGACGCACGT
+
:4)@G>0$;?)C2@$8*0G,4=7D.04>*A#94.2?:8,;$1E(E,%5?FF!$03(A7#=8GF)H8%CG
@r3922
AAATATGTTATCTGCCACGCCGNTTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTNACAAAACGGGATCGTGAAAGAAA
+
A!7**&(G'B+0:/DH2!)8>+"$$F'"D.EB#A$60'(<94H.4G/E7,4!F0&/06A#G%#>((D;109,@59G>/@*/B3(&#-!#0%BD.4+.%9#0)E-/#0D><G2H2:1":"2C1.;385
@r3923
CTAACNAGNCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTNCCTGTNGTGCAGATATAAAAAATCCCGAAACCCTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGG
+
#*())('*%+$!)$!+"()*""!%%"#*""#&*"&'!#+'(#+!&"''*+**(!&&%'"#+'%&&%#&#$$$"&($'(*$%$$&#+$*)&+((#)##$*#$$%*!#&')%"+*"(+!!
@r3924
CCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGA
+
4:A43'A;)$.1&?1.%'B6,4@8)#4061(";<&G):H.5?!1%(6("9#12&3*E34!D9!
@r3925
NTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGG
+
0)-&1:518"-<=@,50CH72E>!)C9F*&E.0;C"/!.33>!%42)$E,;,!(7<
@r3926
TCATCGTTGGAGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATNACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTNAGCTGAAAGCCAGACGTAACAGCACCA
+
C<<=F.%>-&9-!3C>AHF"3!FH$"2162&.4G"4A*>;>#2FB:1&2(/C?*93G0=)%3*F6<"EC;+2A6E5(6,%)5/++>>)G,(6$E-!.EHB):8.;A"D%&(,*2$B08.&0=D$A"2EHED"642C#2B=%653';6,59EG32536&;B860A$#:$2"05)F.+$DA%,"8)85;
@r3927
ACGGAACAGCGCCTGANGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTAAGTGGNAAGAGAGCGCCNCGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCNGCGATGCTGAC
+
*+8?G$7-15&!+)C4<6E:6(2'+:'H#D%7G.F#!"GAC>>%7;C&/==4#(D*%E28!5&DCH/4E)?1("H.CC;=)$9/>%&5*D8270$D:>6G?3062&!)%?62B$2GD+3&?A,A">=:1<4E')7'8E"@;.<?")GF)@?E3$HD-F2;%47/>0!A%FC0-C?'2$&C5=@B'"6,==$&4G;,,96/.#A5$%*-H07D*+B>&+=CA1*F&H0'F@3'G)
@r3928
ACGATGGGTTAATTCGCTCGTTGNGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGA
+
9G6#&//#=A8D>7("!'D7$:'/41"G!<"=0B"9!@9)7*D';/'97)5'<(&H+#9?2.)!%B$'GH#G%@"1=4D(6;*F87"5(2313CA+#9E>617)=#"B+)55+%<59G<1+='$/F:%)$960"4E*#+#+;-//F&285$GADE%9+%CF%F>4@0-!56F:0<-=%7!/F2%<69*:5-?9B++4;@7+=D6B=+:)>)$7058.<G(H5<:/
@r3929
TTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCT
+
A2B=&,6?D?9>>C.=D6.F:8,ADA7BA4#>>>6$:A/?*?@19$&64.+,(/)(D5>@!/D:3>H<:B3#9B=G)2C4/?'*,&5;4!BH,D2/":
@r3930
TATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGNACGTCAGCCCGGAAAAGTGCATA
+
BH46/#/;G,)%"/0A&B)E1(626H.8*6='G./)66->@&HG)B*+:(%D+/9BG(>
@r3931
CAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACC
+
;C'?:GH%,23921'7;52<.%!(?=$G,,60-035B'",45;8!.
@r3932
CTGAACCGNGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGNAGCTTGATGACACGGATGAAACTGACGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCCGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCA
+
=-C#EB=F0?2+B:+<6;"FCD)H%183$A:9<&C1;1&+/B"8):!/B9<5#8'8+0@0-<:C8@>>-8:)&#3(3:DA=5;<'CGD:?0-50;0@"2A,4D1(HD!<-)C=CE8CF"+G#)#??2+5,-:0-$H$D&=@-6584"68@"7-7,#<*,:.&E!:E>E5.H3/-**H;=1'9.-%EAF;A)B;>,$F:9%<(*>?4'2#6!.B.2+=4-'E=6BFE*G=,';-&C:C%%?/4
@r3933
GTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGC
+
3'@.!C!*6H;,9;$+(94.)-!!5F,;.<0E2?,E++@",HC=0?*CH4<''@>4F8;$?).841A477>=<'"1763)6>F@A=D/<<B(7(>C9A0@5%$ED%,.E42,B:-,8#EF*@<'0#><(A=1!;#4,'2:%:$
@r3934
CANCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCA
+
262';/4BC*D79A+>)2:4A+DE#(12)/4A4'A0AC!/A"H??'
@r3935
TCTNACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTG
+
$&7A<=3DE/5)9#;507#C1,-3B>3%H8@A.3>?075=F'!+59(;+6>5="E7;'@@!.(+$FH&829!3H">F#E%6(64+0"2F".<>*<D>$
@r3936
CAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACG
+
>8?>"C6AC69.5;A#7+G1ED$11)6>'>?*?+*7(EH5.+?A#'=#@-(E&>)@,&AF2,+#E&=H:A95074(-'.AF2A'A99A;:40)@
@r3937
GTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTT
+
47:9("+=-6A>H3'2F>2'B00H>07>D7G.(,7!//<)>=E.$84!
@r3938
CTNNAGNGNAGGNAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGGGTGGCTTACCTGACCGCCGGTATCGAC
+
('!*(&#*$#'$(**+%%%*#*&&%*''(()*#'""!)(#""$)$)#*&&*&%))$++*!(%($!)!#&'*(*&%*)&#"
@r3939
CAGTCATAGATGGTCGNTGGGAGGTGGTACAAATTCTCTCATGCAAAAAAT
+
?4/4&$-3A;9HGC+7$&0@3$79/27,96(??D?H)7++)40$C6816BG
@r3940
CNCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCNTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTG
+
)$F!'*7=4,:*!C>9#+?9-7*4+&<7A7:6E64&635B2"&,?587)>$-3C#6)*(?A6<<E)91!B0(@H)!@31<D""<E=5?$=?(!H+99,?F92-4C>E);%#&3#<%3*B@.1)":G)7/>0;$,C@5
@r3941
GAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTCAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATC
+
01E*#DGD,87)-$+"%5(EG7$/71)'HHB&-"<5(:C5',D2H@!6&-FC+%4"()*5;B."(H?+"(1$();8$*"A%4F!A&=,*!CG(G9B&:E170<0A>$D1,G
@r3942
GTCCGGCGAAGTCGAGNAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCC
+
00>FG;0)/$73D=580"7.5C<!*!+/A0=.?@F9BD3;H(B'6-F**9'CG*,C2+5
@r3943
TGTANNCNNGTNTCGTTTCANCGNCGAGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCACGTTATTGCATTCT
+
(%*(%$'&'&&#*(#$#*")((#&!%$+'&&#+)**%"$#+$('*$#!)*+*+%'(*!$+!"$$&'#!)'#(!*%("#)"(&#)%(*&!!
@r3944
AGGGGGCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAANAGCAACCATTACAGGAAGTNNATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGA
+
C:;33<.A(6DG!C17<"&3.<7%5$0()702!#B">3)&&''DGF=@8!7")H#1H5!BG?E41<=31FF95;&)>&'%#C3!6:2'8/=/+&)!"=DH#(12",EBDF%:26:77G1H:")79',C>F%6H&C0::F6
@r3945
AGNACCAGNATNCTGCTCCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTNTCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCANTTTCATCCGTGTCATCAAGCTCCTC
+
$%"*#'$%%$%%$""+)"*$"#*'+!)(%&"$)!#!#'%')'#'()!'!#&"$$*+&$%%&'++%$+*$)&#+%%"("%%'*$++'!'*!#!!#+&&&$'+%*")('&**'$+(+%!+('*"!!%#&!')"'+)($$"+%")&$%)(&%'+)'!(#"#)"&'+!%$*(!##
@r3946
NGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGNGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAAC
+
".9%*C4="H$H1%2=!2;=9<--9+%D,0&!;1=?-860=)'&2.,:1>G(E#,HH1(C:C4-;7!',G:0)'<:42+>.(A#/0;24E@-68<#!&)@9&4%F,3G+3%@'G*(4%??5(=;2%@8>9-&*#!(+0"F
@r3947
TGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAA
+
?<,4#*,D!$-7*A>0)>.!7=*;!>(4$AH?$-F5/!@4>+#-=<0F@<?$&&.'3C.*48"9*#H>&9="050=.44.7$):(608.@?D!0$=
@r3948
AATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGNAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTG
+
&16D&B7A#)?1EGC0E5;%=#9;H!*G7:6=3&B@H>90B9)A8</G(.$""8=9-$!,7/)%E"-*%BD=DD*?@7069"8(/'9%19A<4:F69214'"-F%G5>2;DA3*-).7/>5.CG
@r3949
NTNNGCGCGTGAATTCGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGACGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGNTAGTCGTCAC
+
''$!'&'')#*%!)!&%+!'#)**+!$'**!+')!+'#$'$+#$((&%$#'+'#&+%'!&+()&!#+)!")$('!(##)!*&&'(#&"(##&&!%%&)(#(#%)*$$'+')&!("$+(&#'*#)$(&!$(+$&(++%+&*+("($&!&!"$$*'$#)&%#$&*)!**
@r3950
ANATATCGCCAAATACAGGTAGCTTGGCTTCTCCCCTCACCGTNGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCACTTGCTCTATCTGAACGCGCTCTCCACTGCNTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGANCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGNTNTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGAT
+
#$(*+&$#!**!'%!"%&"'!+%$)+%#')"&+'+$)&"#&%&)#*%)(*%'(&+"%+"+)$$)++$")&'(&""#%*&+"%"+(*+()*&""#$!##()(##+(#%$%(+#&!)%"$)+!+')'!+&!"$&+#+#$!$$**$)%")*$($**$"#****)!#))*+#%(#%!#*"+*&%*!*'*$#'##"(($'!%(*(&!&(%"&('(*)+$!'(**%#($%%+)*"#)'*("'#*$%%+%$+#++)+#
@r3951
CTGAAGTGATGGCAGAGCGGAAAGAGCATTANTCAGCGCCCGTTTCTGACCGTGTGGCTTACCTGACCGCNGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGANTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGNA
+
4HA(*<;AC.51'*C@>-60C6)B*?3-1:,-F43<=HG6=G0G.((B4D2>="4+&8C")(HA$-'!;%316+5&2%EH(<:6-22+?6E8G:&07''0)8-H8FCE:066(27.1'>:(69#0F4'?,">&#7&1;;9D4D61-D&23$A<4<C-86<*@'-1#9E,=,47+D5&B=*'?6=2EEF43:9B5:.)A/D2;!)=$#AF68;,3>C;@.(2B*3;1<<*2A!)6
@r3952
GNGTAGANNNAGCGNATAGACNNNCCNNCTGGNGNNTCANTNNANGCNTTNNNNCNNANANNAGCNNNAANNANNCGCCNGATGCNCNTNCTCGCNCGNNTTNGANAT
+
"!!$$!!#"!$##!"!!$#$"$#"##"#!$#$"$!"""!#$"!$!""!"#!"#!"#"$#!!!$$$$#!!#!!$!!#"#$"!"$$""$$!##$$#$"!!$#"$##!$#$
@r3953
AGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTNCGGT
+
.@!*D,98@#;'77!79/=*-H$BGD8?G-+)@18.E0.G;30*/%"E$$/G+;6)96;&A:73
@r3954
ANCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCG
+
*#++&!"%!""'(&($**%'!'%(#)*!&+*#+''$&"(&+%
@r3955
CACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACC
+
?0/#!$*?"*F/D7G3.@<416"#="'1)"6"=8'24#!0$#=)AAG/
@r3956
NCGACATGGTTTGTTGTTATANGGCCTTCAGCTATTGCCTCTCGNAATGCATCGCTCAG
+
$?.FH6,(1@4D?7B>*,10:8-CE.=<-.8&AC@=$)"71&.!,".E==C+3>0&..$
@r3957
CTCTTCGTGACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGA
+
?!*H$-9D2>:3D>@+!&E#01.%#B-*A%,$@@//1E3G0BA:!<EB<02B$+/B8AG(<
@r3958
NTNTAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAA
+
#)$C;;>E0#1)9<1G2B1,@(?8+&'G$+6-,>0H&=C7))0?4)*</1.A)@6630;F?1!*>=$$<3>C9D=,AB#.2H@+@3C5E:>$>!B7C9"$F('+./*'+
@r3959
NNAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTNGGTACGGAAGTGAAATATGACACGCCGATCA
+
$'C#+/&C!'!4-)76'G-8685H"93*<28;;;%7HE)('-0(=-,@#;;@74'#&!BCD;E8!#C.-!8(+GFE.5!F"@1(>D(<C?)7)6F1B@-7&DG+7B?F>#&):$;B=0')/66;$@37";A@BC?;-F:1H360<9=>"48%8F@>:B9'<">=$(4)6(6$2G?H+4.;&G>@.@05::&79(8(2D/'D.$6;%1/8"&!EGC+GGG$%H--502,=7G
@r3960
CTCCCCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTC
+
+6GA3$90/3?,:-A=(%1%'H=8#FC.:H*97")&H1*$%.D#@#>C"9)1"@GF80:
@r3961
NACCTNGAANAGTATNNGNGNGANTTAATCGAACAAGACCCCTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGG
+
%'*)($$')#**$(*#%()'&"$++*'('''$+"%#$(+'&$#*+&+&#+&'&*!$$)'&)$"#+'"+*'%%#%&+++"+)!'!+#'&&&'*)#+#+*&+#&*"$##!)(
@r3962
NACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGAC
+
%93.B:/?;,+>H"('%"=&'0?,;6D>=$6%$?",'"E"'G0:0>'"'(4.%7;26<
@r3963
NGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCAC
+
$C77:G=7/,7>!0B-0(B%#(%<:"@;@(5EF2?B5*7G>FB,8)@,91$$%"4&8E1E),@/2<C1<?-A"&*7D;:DF*E%>C(
@r3964
TCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATT
+
7/1&=87#D#"6''1BA5;!.'=(*!,=@F37=+#4>4,@.(<8
@r3965
AACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATT
+
=7-"#"-=3<G?FA<F!%,(=$05;.14-G%0C4?+E*4C<;,:?BC@*$$/,!()#52:'00F-F:C-:G2+A(87CF=E'=*8+$4""H>?'1+-,=@(+GB7$?'9%A:9'F#F0G#/*,'?1886;(G@:64!("H8.>B965GA?*0E5.F481;.9:!:=<);&/C
@r3966
TGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGNCTT
+
3##*1&#)*FHE@E?HE6;<A!>D'8#<5H"(1>!1,1,$'=.*<2B#("32EC.>47*=9%9B#.&!D/%F/*37&";<)?)@-8&D<@0)8%-7+*)G"2!0=("$C
@r3967
NANNGTGANNNGNNTNNNNNCNTANNACNTNNGACNGTNAGAAANCNNNNGTNNCNTNTGANGNCNTTAANNCTNCNNAAGCNGCATTGNNCNNNTNCNNGNNTNNATNGNNNTTNANCGNNANNNNTTNTNTAGNNCNNCCNGNNANNNGNNNNNNTNNCANNCCGTGCTTNNATNCTGNNNNTTNACTNNTNNCNNNNNNGATGNTNTNCTNCTNNACTNCCCCTATNTNNNAAANTCTNTTNNNNN
+
$"#""$""$!""!"!!!#!##""$"$#$""$""""#"#"!$$$"$#$#!""#!$#$"$$###"!!$!#"$""!"!$#!#$$"#$$$!$$#!$#!"$""###!"!!##"##!#"!#"!!#$!!"!!"!"$$"$###!##!#"#!!$!$!$#"$!!"""!"$#$$"#$#$$$!#!!#""$#$#!$!#$#!"!!!!!!#"!!!$!"!#!"#!$!##"!$$!!$$$$!##""$!$!""!!""#"#!$$!"#$"
@r3968
ACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCC
+
&2D.<$&;(&6>.$.<-&;"H:++071B2"8!%HGH@32)(,H
@r3969
ATATCGACATATTTCNNATCTTCCATTACAGGAAACATTTCTTCAGGCTTCAC
+
$(3AF0E368)E(7?&D6;1?%0>')$!!4<A&$/C$924->73&@1*F5,CA
@r3970
TGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTT
+
>89.5*8#<&5$2=894B.">6>'!61D"E=E*,"/'9G+
@r3971
NCNACAGTATCNGCGNTATNCCTTTCAGNGGANCGGTTGTCNACNGNATGGCNAAGGCACTAGT
+
%#!%&%($%"&"##!!"""**%#"(%&#!(%&#()%")#'#$)(!)!#)*)'%&+!&&+$&%%*
@r3972
GCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGA
+
++&*)(+*")(&"+($&&!")!'&*'!"('$+&''"+!!&"%!#++)(")('%*%))")'''%*!!(#!'#(!'###
@r3973
CAGAANCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGC
+
H@&2<!)HA)<A=?+>C=GF=H2/8"@2=G4*3144%/88$:2<73;*(FFA&;#8&0$:!
@r3974
ACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGC
+
(3&;//E884B"5B?>BA04E&8!2%(5E#()+E21&=@%//2A:#75/6;B#$"=,2FFC"=::-5**;?",+<3)D#(*-'*GH4F:(3G!#="EE73+//5C$F6!*8'58"G&&4,%2!9)AG+:?"639HD@H$(*E8C48H"0%;%<:A?7C>.(5?6//E/DA.1/6*6G#=)D
@r3975
ACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTAAATAACGTCAAGTCAGAGCAGAAAA
+
7=B7;?"6+?,3&06%F9!88760!#5EE24G)8.?3/&BA:+.=:/B2C2#,!!!+@8:77%2-@*+CEF3E
@r3976
TCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTNCCAGAAACGACTCCAGTACCGTGGCCTN
+
G@2,.C?/(2):%2FE,D'D=8)'B27A+*$>#6<?079;-23'*@**6/7.$B-8:9'=&;?C09C6GF=B%.C8")'91HFCC-!2??-9F
@r3977
NGNTAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCNTA
+
$)"+%&*+(""!)#(&'+&*'))#&*%(!*"'(%&#$!%#(&(#!#')!)+""$(*$"*+#*%((!'!'&"&)&%("%)&")("%$(
@r3978
TGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACA
+
4&3',0$C9&6";51:26B1-1GC7;.=,:?(;78@>8$:,*D+A*
@r3979
TTACAGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGA
+
0!A:>G-39"-/1@*HH&F,;%*;'37&,6BC*?,3);0:$C)&-@%5(,@6()1*8:'C"2&'50E'2!:C<;;<>8)E5,@
@r3980
AAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGCGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCANGACCGTGACGCCTGCCAGCACCTCGGTNGTGAAAGGGAAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGNCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTA
+
3)7,C3=!8.!/#E,8?/0G-%7!'6G:A(C4(3)>%!B!0!DAA+(=EED8=?7<9::E&5>&ED)D790'@5D,A78=;DG"A*%=:5;(+?2F5%9AH>791"5';F9?.HA%;H77827/G7:.@H@,B*7B@=,>'D+?GGF"A-)H/0'9DAG#)?'G2**7!9+.&*->A.%B+1/:1%/%F,7G((&4A?4=$..=)A6E28:@),2,1HA!+A@H#6"G6F-.&C.>2G)&G-B5"?C=+4;/E!CA=-*)F!:40(;3AF?+!:('&+F0!8'C$6<2'H*98D5D"*B(<F%@G4..A7:DE:2F#E4007&;F5.E>,:%"G<*=)"'%9-A5/D;<!>(,D?$
@r3981
GNNTATAANTTTTTATGGTCCGTGGTTGCTCACTCATTCTGAAT
+
"'#%*%###+"%+$%!&!!$&!$)(#)*"+%%"&$#'$&+&%+)
@r3982
ATCCACATTCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGNATGGGTCAGCATATCCCACAGACACCAGGCCATG
+
;C6--<CB56'/+3(#AG;2H13-,2=49:?;0!"E*:!4!D9$#187>5H566=@6@1F0+-&(8;87G1/#7/%>D.
@r3983
AAGATTCNATACCGGCTCNTGTTCTGAGTCATGCGTAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCT
+
+F="3!'9,;:/#A3CFD.55*/.9!<"FA%3<67;&:>(!;@("2<5G&:(*5CB+*E#E/@-C,3H3>2:28%470"
@r3984
NGAAAACATGCCACACATGAGGAATANCGATTCTCTCATTAACATATTAAGGCCAGTTATCTGGGCTTAAANGCAGAAGTCNAACCCAGATAACGATNATATACA
+
.*8*6,GG&!(,A6;+;D#:7?16(:B>E3H-$GA+;*G)".)4E':D"=C32$)?B4<H<C44<&?3<2;1)&77%7)%:G&?2G.33=@1!#+>#'<2.1E:4
@r3985
GACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGNCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTT
+
>:+B7+H)C0/"13%CC$.B>$$/A>5,'-3),+.<->0G#4?0";*0#95FH<*,4@=%(<!>"+*HGB52H>..1&*HG,H#G:F=H"$6A%
@r3986
GNATNAAGCAATAACCCGCAGAAAAACANAGCTCCAAGCTCAACAANACTAAGGGCATAGACAATAANTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCG
+
*"*""+$%&%'*)+%($)#+$#(%))#!$*"!$%%"(#+(+()+)$#!%!%&#(#!&'&*"*#*%%+"'!&!"!!*#'&%)++!")*$"%%#&!)&%#&!+&!+*!"%*"#($((
@r3987
GTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGA
+
42B)@54!4?D;@75/,?4?-H:8,$F#!D(28>G84??)"$B%&%$%(:29HH,//8C3E2=>+$&A=AFC(9/27F;'%>";+><A
@r3988
NANCGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTA
+
!(!!#&)+($*'(($*"*!+*(!("')&&$'((")!%("#!"%
@r3989
TTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTNAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGNGCACCAATACCAACTGTTTG
+
3=$?$,-!0$C22E>F,4.F-CB0D$(%-6G23C>H2?/-!,D4HA'=-$4HA45+%0@B@B%!',+H6C($;6!,)!BFD;1C@4%-C<;=E)AG%;>*<;/;*-&9730H8->637'!*:A1217;(:);B$$'!#2-#:;77F*:A8."*@'C)>3:A".$3
@r3990
AAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCNAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATG
+
C3A/&,%6/%DD:-/7!B99@/8#-6$C>+%.$<D-=/F4G<?H>G?==-7/G3")"6D'&6>=2D:-+)0B$@7>B*005=ACG(3.0@2::',B;6C,2)!;"&&;=5<3HD,A;/0C1'<66:BA9*47BDD;4HD!3G9B)$;=(7633A'!$76FC0B43E;F.20C,%2A7%FC7C-@9/<7",GF<28/7)1/FC),G'B9!*4DD)%%D%3-G>=1GC#(0&?&1D7;,!G<8&!,>=0
@r3991
CTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGT
+
%86C5"3#3AAC@>7/-?E,+G!%%9@,;"5H0%()6./'8,8A2<8H,;%@'$.B@%,G;@=/3)A93D41
@r3992
NTGNAGGCNATCNTNCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTNGA
+
!*#%)"%(#(%$"+(+#'(*!&'"'+"!+"'#%*&&"&'+%#*'%&%"$#))'$)$&"%*%$*+"#"%&!((+(&'()!
@r3993
TCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCACCAAGC
+
--7C8&>G'29.%;$E*7-6FG=B=,'&*.F278F$@-)!E*7=+39).!#
@r3994
CATATGTTGTGTTTTACAGTATTATGTAGNCTGTTTTTTATGCAAAAT
+
.$<.6)CG-3*H5+11D%BG(#D&00.%C&>*+56!)56CAE>B%&17
@r3995
NATANANGTNTTCGGTACAGAGCGTGGCGTTAAGTGGTCANACGAAGCGAGACTGGCTCTGG
+
%)(($"!)'"#+*&#$#*#'!)$)&$!"'#%!&#)*"%+'(+%#)"))%"+&"#!$!*%*&)
@r3996
GNTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAA
+
#%77>G>A@!0",7<*;62"-+><)G=6.A22%G(@1!*1%./A9CE1+B)8!<G4984>?62,;
@r3997
CTCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCNACGCAAGAAT
+
&"+'!()+'&&#*%%%))#&%+**"$)()!(+%+#!)$!#)#(%!"'$'(%("+*!*$%(#"#*
@r3998
ANCCGGCNTNCAGANAATNTCNCANANNNNCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGAGCACTAAATCCGATAGACCTTATAGTGCTGGCTGAATACCACAANCNGATTGAAAGCAACCTGCAACGTATTGAGCGC
+
'$"%!)!"%!!'#(!("$&)!$'*"$*$(!+&'*$$'!*$(%)$$)$*+*%%(+*!%"%!)*))#'$!("%&!)!&!%#$!")+"$(!$%!!)$+%"%'&*"'#%$#%#!$*"%)$+()$*)&!"!$+$%$(+%(+*!((#+&*%"*)'')'&+"**#!'%+"*!$$*!*#*+#!'#"#%"!'$#""&)
@r3999
CGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGT
+
9C0B/G)2'?7&+)@H#!A@;EC0*;0.%-'?H(>0,?9-5
@r4000
AGGCAGGTCATTGGCAACAGTGGCACGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGA
+
B!D)5;:8>37?>A='=5&9'A/>$.18;4$A87F9F-;%&B:BB#0-'<8#9:B%<+H00-DA2E8!5-.7#=H%>B#
@r4001
CNAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGC
+
57"<<$G0)5"H-$;?G(8>E@G,7H'B3G<G#6C-/-7G.$-,'
@r4002
CTGGATGCACGTAAANCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGC
+
4/D:<.:5<(1=.*E%=&)2C?<;19/($@C-47)1:#6#+$F($5).%(A86-%...!46/-;4'6A4)3GD!(C4
@r4003
ATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTNTCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGC
+
G+42)G?8)AE6GG;G5&)5/%D4DGB2!@,G<@@'#.(/@68)!B;@:$14@*-2:;$4H*-9"G!7AC*%D'@+.H.?9G<$:DA#35!)%=&+4;;!:<8C/07H,1&37)GE.BG/11(5%%8
@r4004
CACACCCNGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTANGAGAAC
+
+,H@,C?(CA?(9'?-+<$D1G+7'F!F*-"C.AAG%'D2?8:=%+H;))/;%CD*4=CH:B!3,(-&72)#0(;-::*.>;<;
@r4005
CCNAACGATTAGCTCTTCAGGCTNCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGAT
+
*("#+"*!+%!&)!!##)!($$&*$%)&%($&*&#$#%#&(%*+$(&&#*''%#'"$"(+*
@r4006
AATNTGGTGAAATCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCNGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACC
+
9B-'H1*'C1((')%8@6,C18FC3$G4B14=&EG6.2H8=>0BD(C%+:%$D->.$5H#'?'D@3+2?,79,"!*#C+H2;.9FDD5!9.:&:0*CF#;G-"3<H0,>1&B@2$48?"3&8<)DA:?<;AF&33**D1C4#"B(/GE.H,&*1B347)C>A@$!1<+H9!+7=G=+E2<<:?#07&#4!>F*(5/"$:AG$?+#>2+41'#8/C>&E./9,0%B647(3>>8B%A'F&.3/(>+';1%1)3@:3$B:;-B,7D6F4+!;:H!###;2'37'02!)
@r4007
NANNCNGCNNTGNATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTG
+
$&#!*!)*$*&%"+#*(+##+"#"')"!&$!"#()(+%"+*'%($##$+%&"+)*+"$&%(*#+#$$#!'"""!
@r4008
TTTGAGCNNAANAACCATTTGGNGGTTAACAACGACGGCTCGAACGGGNAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATG
+
)'&&&&(""('"(&*""(##*"!&"+)#'!)'!#))%""+&!&)+(+)*%*((%(''$&%$+(#*$%$(#*&&)&#&%*$"#&"*!$
@r4009
TCTGTCGACCCACAGGAACTGATCANCACTCTTCGCCAGACGGCATTT
+
C12.E@!1E9>@=.G&'(47)A%"9<')G+089F(=B/+@$(5?0%/8
@r4010
AAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTT
+
,/.*AB2CC(*:8D@,?'EH*EHE5!E9?)0%;&E&/:/10C
@r4011
CAGCCGGTAAAGATTCCCCACGCCAATCTGGTTCCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTA
+
'&)21E99<A7!A8:'88C<.C."&07)D/H9+4C-G+,#24?0>'8*>/D"A2"?'04<+6!A(21D;0H!<H%=;A252.A;4/EB/:&>$)@C294%-;A55
@r4012
ACATTCGCTTATGCGCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCC
+
,!7(+E<"A-7'E4'"'$'<,)"'@;<+D1D*":#-!:!+6FAD0#;F(16;5/-D+39#$"@>@H8>0<(&.3D8,,0D7("!$%:C6!8,B$DCB3#H!!BA#,G?>:;.8=D%E:#5DE0C:)6(50,:6?D8?$+5/,:H"3DB?1@651(6@(@59CHB?1-
@r4013
GCGGNNCNCAGGCNNNGCNNGCAATATGCGTANGACTTCGCNGCTCTACTNCNACNCTTCTCNT
+
)!)$#!*""$"**#$")"!"%)'*)$##%&!!!*(")$$%%&("%&*)#%#"'*%!((&'&&#*
@r4014
GAAATGNTNGGNGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGNAAACGTCTGTTGAGCACATNCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTC
+
:%B6,'9,A$?5<9-%GBBCH/9DA,H>F%@.7++E51)3>2H:D2?>7.9,$::5DH9;97&":,;C,>E%<+55,,$&D:7@'3G,%;#9H1H$D4,+(15?8.<H=$2$)*4'C5E;D
@r4015
TAACATTAAGTTANGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAANCCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGT
+
$E2&,6>B>?%6D95H!-+)D@3+&951D,*0:"D0)@?;>4D:?(F%,$'*B!FE3CC1@"H8A-83$@6.H"H7:9!AHF<(3>5@</E2<-:<*./.(>6!1?,:'?#(F;!/!@E'*0!/$$ED2=H,F%?+D7$2.3-'=5(//CHC'1
@r4016
GACTTCCCCACACCCAGCATGCATACCTTTCCGCCNTAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAANTGGCTACGAAGTC
+
+%*$"&)$&*($+"!'(#'$#$''$&*#('"%+"%$'$&$)##)%(($$$'(+($$&!&#&*%(#)+&#&%)+((&"))$*)$(&$###*!'$($&)&(%%)$($
@r4017
TCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCA
+
0.CC)'4,851?@D4&:=6G>%H/;$5DE:$%/7B7=")C7.;D26*&5!@F5&C;?";<C7+)?58./6:),!7#
@r4018
GCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATT
+
G5G#:1C;=7)%C73&%<%.1C$-H>4&$@7,18=2>)>#/22'D829A.(5B;G?/%?A<6>C(BH./A$>&/4#$>#14F)G/-6(5">2==,CD409-1*BG1BE05::D0@&>;-=%*1)&A56+AE#,@3@=24*4D0&,-7,(!H6-";"2.*4%B2.&11BE:!0@%$#:8'079,>+(F&@&B0,,*C7%=&>"7:)?<:/'"E>(,#EA!EB.)B:"0>(#B3*"
@r4019
TCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAA
+
B(::!?0-'//7.,B26*H@@<6>=(?+=?/7-H0E63:9*E2*H-$92'..+";85'D5
@r4020
CTGCAATCGCGGCCAGTACAAAAGCGGTGTTCTCAATCTGGGTATTGNTTGTTCCCCTGAGCGCGGTT
+
1H(%1903F6=8('10F*'9>#A"6!<G7*E;?*4F4G<F()2#C!49+D&>0A7-(E*!AC&A$)(3
@r4021
NCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGNCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTC
+
#+!"&#!%'&!*&&&%)("'$'#$'(!**(%"$"##'&!%#)%"))"$+%')&'!###"*#(#'"!#*!!##+'!+*'"&(#%")&!")!((%**"!!+(&*+*)!(!!"$"$""!#&$'&#!$)))&"*&%#&#%+))'((!%!%%+%&*$##$)(+&
@r4022
NNACCGGNCCTGTCNCCGNCNGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGNGCAGTNACTGC
+
&'&('$'!&"*#!!$(*$#"'+(!(!($)+&#+!*%!+&%&'+(#'+*'%!(%$+''%!$&!)!&(+"$$$'$+(+&*%($*%**"#'
@r4023
ATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAG
+
9')+5A;<'E#G'G2&HH'8D(6A#"3B;#<D6G&?&,9-AG:89>B
@r4024
GTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTAC
+
H$.?7AHD%,88:;'09+;>C;G%-+$DD.*6H,D:+C0'F+E&5
@r4025
GCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCNATGATTCAGTGTGCCCGTC
+
=HF#57G?!%,%/3<B&&F0#"H"1G=3%"-+*6':*FD03<.##H3?1#$G,@!%G4$HF%'F$6-)32A1:6+77)
@r4026
GTTGTTTTNCCACACCCATTCCGCCCGACAAAAGCATGAATGTTCGTGCTGGGC
+
0?/878%(=?2-6:-27($)F4*E;/!.3@5;&#6GH-6,@%G:(GD7CH-;;A
@r4027
AAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGC
+
H.?1-%3$=/DE#-8HE*72;+,218>'0+?=A+6F);;-A=E<0:;'E,37
@r4028
TCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCGTCAATGGCGGCCCGTTTTGCNCGTTG
+
5/&"C.4+@F?*!A<?(1?B#56D@</9&()%/!G8'&640/+9)79'0/8F1$!)#D&2<GA35B0E0G)7+6GC/
@r4029
CATGGTGTTATTCCCGANGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTG
+
?;F,A3%(.D8"G6:H*<F'((8->!86&G4=70/2B:1$7++:E6!&6%=+"3<8+G>9*'93B$9+2#>6D2B.8:<5D'A<-835!5+;&
@r4030
NTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTNCGTGGCTGATCCTGCTGCAACAGGGNGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTC
+
*+)%'"$!'*#%)$#!*!'!&'*+!'*$$'''+&&&*'))"#)%!'"%"*%#+'&""#*!")#!)$#$##*!!**"(&)($!)*+++!"!#)%$&"&$$#!*!"*&'%"()'"&*&'+(!!%!&)
@r4031
AAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTNCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATACAGAACAATCTGCTGNTGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAA
+
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
@r4032
GTATGCCCCTTACTGCTNCCTTTACCCATTCCTCAGGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATA
+
,11)H7<.81F:<8*$H>5!<!!%"7%4!"1(0+!;&G!+)!%--H40<%<'+-;94<F!2#$5#E#>B9*;DF<#@
@r4033
GTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTNAACCGGAGTGATGTCGCG
+
@,&"%=6!9>E%3(.>93C:7E7??9:8H10<80$A:GAC5G!5*"=G.;H5)@6'AD3%C?83?>0B4#H
@r4034
ANAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCG
+
*-,D=.1?<&'%7E@8/6>4-?2-D)>*8+H"GE=-)5-<AH+72*$&94
@r4035
CAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACG
+
38,>G=B."=1=H7"16"G&<+&/3?17().))+!H&:439)=5=5>1@(8)@8>.;..+C;C9?1?4:.8->!2F#"-"&+!0%."<4C#DF1(/*1:G)B1(-#%69&*7=..-B2A2)/1G%B=CF6=2!7A;/#'9<#'>?>(9$747
@r4036
GCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTT
+
G@C61"5+$,3&;#F&G*.!.,-*6<D#B@(GC'>>#@</5)$H/9+7?91*74,98A8<8,:?0&E@==G?&E50(D,G.)FC%#</B3)&+
@r4037
NTNNNNANAGNCNNGNCNTGNANNNNGANANGCNNCNNNTCNTCNANTATNNNNNNGGTNG
+
!"#!!!#""!#""#$!!!$####!"!!###"$#!$#!"#$!!!#!!!###"$"$#$"$$!$
@r4038
GCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTNTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCAC
+
(+3&'%:B=*-#@34+(<<!8F;0C!7!*A;A@6$?60B%")F-39>4B)>0FEF:*4.?A$DF@"E#C@1299A..)2)6D$?#3%4?+/%>5'''7)-8*:;H=5GE>B
@r4039
CAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGNTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGA
+
)A!!.=1"G4A*!2951.=38A?-B23"'F#=9)#:0?1G=12E-=F>*@C=8,B-=')7EE234(=04A?"EC0B9@(";(1!1?0=9=C+%<H$6C)$(
@r4040
ACCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGT
+
!H<D):/B/A.*<D!1#H")6?'>:H;4%A<-C(D74<@67BA,5/B1EE8!3>+!8>H+:BD#?@:#)
@r4041
CGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCNCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGNACCCGCGTATCGTTTCATCGGCGC
+
"%'+"#!!#%$%+!+$&#$*+$$&!*)$#)#(%*#&"#&"'$&((*&)'+'$'(((&%""%'+%$$&+"&$#%"+$!(%%#(#!'*(#$$))%+!##&)%##%$!!*+*"&$$'#")+"$%!"*#()$!+!)*"$$(&%!+
@r4042
CGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATC
+
G8?-D0(3!3&9,9./5&*F/);'%H5)5!9*H67!,5!-8'?4#=-@<?@*G.H<.(DDA?8EH:510BF!;(*9A4,<-4G26:?'>FC#0?)H>H+H"@G:B2:4,,#0E82C8G?18:7,F+"E<7B
@r4043
AATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCA
+
7A>2(2?H+;-17.2'$-GGC2?172/EE==H41:C=(:*D;&)?$G'?:2E;2G.'+0((%)24",
@r4044
TTTAGCCGCGGCCTGATNTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGNCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCT
+
7!90'@A)B=794:!/1<@;/E)0D9=%!<1:<0=24/$B3-"&==920!<H7<8D*6B!;!82G0.%H'E!&.)".%G/#<%(54,83B2-.*F8(/F4*+))61D8?DB5<2"<HFA'D)"+<$
@r4045
ATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTCCGGGCNAAAGATGAGNCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGA
+
<5(,G=;C:G!&E8,:)5@<:8<-/#13F4E#B3&0@8"58##.'!)89."*&D"F"G-@A>()%<.3"1(/+6B?BB#%1E=#1C;BB6<B!4F8-$*AFD1<3)C+."<+>1.-2?>E&=)=<?:</+/+.E;A
@r4046
TGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAG
+
()=#+?@#6.)<@CE#A&,>D2)!+4>+/-/'"+=.$>ED$+F=;A!3;?/"-073?H0C@%=$5;B1$$
@r4047
NGAGGGGGAGACNGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCANCCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGAC
+
!'*++!*$$'(("!*+)"#$'*&+!*&%&!&"+*#))$!+''$&")*)*)$(#'!)!&(**"(+$!$'"+&#!%!#"%!+$*(&$++"!)'&#+&")&!%)#*"'"#(&!$&#"'&(+#!+++#*')*#$*+#'))$"#()+$**+&(+**"+%*")#('*%'$$"&"#)+'%*&+#%"++(#(*"&+(!+#""##$'*%(#(++)!)""""+'*+'(%)'%*$&)((*)'''"&&%('"&($+%+*"#("*)#!&(%&+#)%&*"&#(+$#+'%'(
@r4048
CTCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCT
+
"<C>1,:34";6B(96*(!E@(<F8*2*=AG4576.(;:F532C;&!3=C@4C;6=1==A@,6/70A%.#'*EA9.@,D5$"%H&@G=(:568/.4'@56*;"FG#$F&@&B!G0&(E8;"G;/,=8D%7
@r4049
GTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGAT
+
<F/91"$43G0@5>D2/=F1=*,"F%2#,9A5C83-$HBF239%:4AEC%26,?B@"#1:(/:,@B,3!=E)'=E@?90:4)/:"/F%&H?;=5F@(A*;F&7;@(%D(BF9$!)-7(C!E)'*2G8H-F/-,3)DE9.42=-;"!G<@%3H2?+<1;<*".30B$:2-#B:/;H9$@#9%F#H.B11%G*59?%+2(;<:$?@#G<+$CA36
@r4050
GAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCG
+
=.95<+$,*=$;2"#"7)$'.80H#+A4+.%#9?("%8-1)#;.G.F;&
@r4051
NNGCTGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGTAGGAAGAAACCTCNTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATANATC
+
!!%$$+)$%("%$)&$(*&)*'%+'')#+$+++!(!%"&)+#%&$*#%$!++(($*%++#&#*%*'%!!)&&)'+()+#&%+!#'+!$(!*###"!+++$$'!%$'%"%'!)#)&$"&##("()+""%*!+$%"
@r4052
CAGAAGATGCTTCGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGNGCTTTCAGTGGTGAATAAAATTGGGTAAATTT
+
G5B#HBE;+=::B+E3H/H5C$1$#9#4B?)&4AC/+.5+:1)!>,8D><*,D5F5HHA(")/93;!"@;9%)1#1)58#97;0!3*)9D@D:
@r4053
ATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAA
+
&BCH#G43%40%.<$<A@<;G!A"03(D.<>6/@$3H%%74'3H.@A9>%'CH1%009D?$&-B="$B$&'+$H)-%9019:8<E%G>!=>@
@r4054
CGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGT
+
.)4/+E:&5?251H#%*25#$&#%;<03E(4!4E5B++0$G,3"1&)>AG7):C(0!?)%"@#E1F)8?6C/FG#.5G"6/?2-B5)0B3?5H''6#.*B%9.B/'8%(:9580B#+3.$'$EH#<94"1>F(,772#".H,-#"";-'.-5?G(@)C)C$E
@r4055
GCTGNNNNNAGNCTTNNNANAGCNANCTTNTGATGGCGCCATCCCCATAGCAGCCATCACATAAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGNAATTTAGCTACGCTTTCGAG
+
))!$"#!%$'!!)('#%)"&#!*"%"&&$%*+"#*#+*$)*&!+$'+*)(!"('#'()*#!%&$+!)((%(()(+#(&&!)%(#%"+"))&+$((!"&(*!$++%)*$$'')!))($*"+!$*&+$#*#&+#*$$)$###&*)(#"$%+%"*"
@r4056
NNTTNCCAAGATTGGTTTGGNTGGGTCTGGAAGGATTGGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAAT
+
#!&%!'"(#+)*((%)$&()!+%)!%'&($&"($&'+$&!&&)"#!!#(""*)+$)%'%(&()''!$%"(")#)&'#*)"%!"#
@r4057
TCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAA
+
FE.B)?<*91C.4+#%+?0@0.C5"28BB@=G?"&3<3CBHB&>8%=
@r4058
GACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAAT
+
5;0F#>)-<"EAD-H!#H+E6A>F$7/?5G4H!-C/:@90H##0F*/
@r4059
CCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGA
+
H3+9?&)G3*?(#0(1?7&?7&=F:$051072+,4*H=7,=@F$?$7B1EE4.4%B6'8<=
@r4060
ATAAGCCCTAACAGCTCCGCAAATTCGCCTTCACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTA
+
:51')H-&>37GC*@&,8=AA)880GH@H+#/*"+>:+<"?2H3"#B0"D5A'=5'DD?.90#,&)$*&C#/+E#.:%%9;-,"+6<4=75(7@?B.F&@*C4%C%0.0D5D0'A-A%5=
@r4061
GGCGGCNGAGNNATANAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTTGCAGCGAAAATGTCAGCCAGCTGCTTTTTGTTGACT
+
'''(&&#*&#$%*#'*+*"(")*!%%"'")!%($'"+'+!!$))*(!&")#'"!*&'"(($)(')&(!($$*((!$#+"&*!%(%+&*+%"&$*"#!$$&*'$#!)'#)((+"((&'*(&++$)*"%&&*
@r4062
CACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGG
+
80.8E+E&)HEF75(E*85G@C*.-C+F1/E/A(AA6/H.$!(@02:17=(<27!3&,/?:70(@/5FA
@r4063
AAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTNCATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAA
+
4;;D:84GE0(A-A-A;61-B.@F-H;$6+78.(2&E4'=22C<(5-ED#.'"5%-+0=6-D.8%=#>F@4?(?-(!.0#D">35F.#3"FD28181'-C,<25#<E"29F81=1B*+'=(.B'8D!0G/B79"+>$#)
@r4064
CATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATNGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTGCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACC
+
F4-$3$CB69=3-8->+G))F7,"$F<#'B##$9&=B0379@DH@8D-E;C=.0(%8*B%5!)*6*?FAEH5.'"<+(85%0%%38$H=$=5:(AH'.+%H5*'9(2(.7C@E-:"<#(:&B,A9;G55FD+1E%+"D@.,9H5:!124842E<G@.B#'G7*&8"*6$3'
@r4065
GGCCTCAAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCA
+
;C'2HG9)?2</5>*2G("D&2-!!7,",/))&+>B#-$=G.F7,9//GG>-#CH#8?':B!F3(@#:2E1;5D?F(A)*?4*;+6)0-.;0;51'FG6=BA
@r4066
CACCGGCACTCAGGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGA
+
4(#=/*,E*?/<",CA&&$)/+1G:;?;@4A;*&+#-#+%6A?92<4*4+086;6H';5F8+9-
@r4067
CACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAANTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAG
+
@4'/B"4H*<;5AC@/-?*5/(#=0=45$*,<$F8@E/B4H:A'>3E481%+43$'88G4(@9);#1+@(#4#E*GCBC.,B7',42BF@):(FE!<&C7'BF)(8H(@:/G0+0+24##%$6!4##&#&8(D"
@r4068
CTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGNTGTCATAACACTGTGTTACCTGGCTNATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTAC
+
@+G-:A/(3?9*'9++F:2D/-+532<''@ABG"/AEC=.2+'&#B.;2H:9E.+4C,7+C55-C%/-$)=GAH%+5B+H80"$00;5D9:4E7G?,9-.17/"3"BE'#9.51)24A-)C<!>
@r4069
TCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTNGAGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTNTCTTATACGCAGCCTCTGC
+
;0#6)G+9@-0E2.#&'!,"@5:C2#8$$'3//@"?:;;44#HB<51;EB!:6-C*?=4"=&!?+3.+"<G:;>A&*3*)6<".6*BE1#+6G4:#0#C;2A4A65&CG-=D2DG$@&'..*HCF=05B'5B2#4;><4:?4("$GF6284#%>"&3B4H$D/2#60"BA"-$DC5%&*H#G(0E692!@&,!"<;8%H(/%**7>F3%H#8(;4
@r4070
CTGCCTCCACCGTGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAC
+
D+*@BD3;&8;,BG=$)654:?)<7F8%%<%:,*/04@)5G88*CA%C(3.(3*7,HEE%#?56F)>B$&:@>9#)>$;$'D?$H5*C+E+)#F3==A31"<=!B
@r4071
CGGCAGAGGTAACTTTGCCGGACAGGAGCGTAAAGTGGCAGATCTCGATGATGGTNACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGNGCAGATCTGACCAAGCGA
+
+!'+##!!&$*%+"&#()&)'()(("*&)*)""!)*(#")(*&$+&"''+(""&%*)((#*'#)*')*&((*+%+)*"%%%$&'#""$%!#*(+*()"#*'$('"")%(&)##"+
@r4072
TTACAAAAACAGTAATCGACCCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAACTCATGGTTATGACGTCATTGTAGGCGG
+
0>"571;7)E2!>DD>CB7G5*99GE5)&@H"A+#,D>9'+1985>G#C.@1$()80#(;,1-)B"@1+:.+(>C/DA)B'91,,%:/BD24.E$/)H?4F&',C?.-1%0A2G20).&A,;>7AH2<F%=9#:*"C5BA0-7@3GE4<8+?@(*-F3))20B=1*92":#C24C41;+*5G@2'=))<58D@DE+<)@;:$49;;AFH?:1%B!+>@>5!F<'(C1.(?+>:&A<5,A-8B9(*@B4$0;#89956+5=##A+)CD3%7+-'("/"6!'DA!1@$,6)(*D".-EC22
@r4073
AGTNGCNCACCACGCGCCGCCAGCACGTCCGCCGGACAGGC
+
*%))$%!*$%+**))$!%"*++)+$(#%))&'(+"&"%()$
@r4074
GCTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCN
+
)&82+*%5DHD,9)3*D*(E&$H+2054%#!FF2&,:))A"+4+!H@B!5&?.6?
@r4075
NANTGATGTNAAACNATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGNACCTTTTGCTGGGTCAGGTTGTTCTTTAG
+
"'"'%)(&'%'&*(%+!)#)+('%#!'!$%""!!$!"#'*$**&#**)#&("&+*#%*)&!"(#**+%#)*$#!%&)(*%#$&%#+
@r4076
ANNGNNGCGNAAGNNGNNGNAANGCNTGANNANTCAAGGNTTNGNCCAGNCNTNCTNNANGANNNGTTNCGANTA
+
#!!#!##"$"!"$!""!!$#$!"$$##$$#""$"!###!#$!!$"$$$#!$"$""#!###$$##$$"#!#$#"#$
@r4077
GACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACNAGCACGCNTTATCTTGGTACGGCGCTGTACTGGGTAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGNATNCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATA
+
.%2@0C%-&@,<"#:5=A&=%B*"C!=936)"13:''#,/->?".9>$338C%6(.GC%DA$3$;:*!>/ED29-AD$A=ED/$<#;5%GH<!2"'2E2:/%GF2BH5D(93*2>>;,G48*=::BC%,G<;7E5.5*54;#1>==-H;)FA5G=:56A!)FF%82;1)$#&9,,-E72F+0"0-E1?FB+/AD5(<-D9:1?,F<+D59E8"AF7&"18>.2=9G6HB9G3#54),3DC"@H!9?'>5:*=;2GD=HAC.447>0@HEBC,13748?4%7?/2;E%;*>/F'/*>D<%1%&*%98AG6<+'A,E9.#/G,9.$;*90!:H)F8(BG2F-;F0(2$,C->7=:!9"3@.E5'5G-*C,1-0D@A64E">?ED3"C%E%6)&-4&B'/?8=:F%ECF<B.#G38"@"2-*!/'3G=#%%&/#"(?0/E?H.*E/1@5:$$))%9,62$6*B:8&=)E;2/+)=>%4)2)<?$"9F2@(:&+"E%%00/&H
@r4078
GTTCATCGCGGATGGAGTGAAAGAGNTGCGCTATTACGAAAAAATTGAATNTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGA
+
=:<1;,&#&$C7F=D*'!C836'!DF;B&.C3+<.-&@&./4(='<7*&,-!14-/$F-AE)D'?G%<4,+@-<?%)#.;;8$,1(D
@r4079
CGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCNAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGGTTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCG
+
E/!?3)EB,+-9-H@B5.&A%8%=$G;(5B1"(@1@='4F6$G/>B3(F6B)(5<5<9#-92&6CE99(,)%2G+<%.(;.0"CDHD#AC;*/2H7>H0?;6:46--4C-H55F@0!(3!D'8*7;BF"61=113G';5>%<-4F=5:6-!G$.*.'E;7$;.6HE@&8
@r4080
GTCGGCGTCACCAGGTTGCCCGTGAGACAAAGGTANGCCGGAAACTGGTAAAGGA
+
/4&#A"EF#E,(=*?E3;4+'04G?1:CG0.+D96CC0"6@%B%1F>&=6,43-,
@r4081
NTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAA
+
%+-&*&&6,##07#E2EBF.*/8+)@7)4=/?$G23DH(:?AE6?.H=(%*29G"7E
@r4082
NAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCAT
+
"C.;H<$<@)F672B@F;0-+$$#9F4/=4G7?$C;F8(B->&F93A>A=
@r4083
CCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCNTGTTCACCACCACCGTGGTGCTGTTACGTNTGGCTTTCACCTGAATGGTGCAGTTNTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATNCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACNCTGTGATACCTGG
+
0$;?*F%@B>0*6+@>2B***F(0;2(&*6D<5&6DB&'$43F&#D><6.E6D)H.B'%;%)'85>F+5*G4-$H(3F8.@*4'37<6:,E<,C?FD?DA33:.D@>6.72.@D0:3AE90#.@<)'+*(/<8;*D+#";".>7>?==.%%9'6B)2/"HADH>?%0511083=#(&9?%+!*#26<@(&;00D!,E%!E/,&07E)"D39(61$2,.63H%!;9?".$'-A6H:4#A3+H(#%:/3&6"
@r4084
GTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTC
+
3+8*BH%>4/%1!!5<;/C>H>F*/:B=A5%FE.C:.D:GCE5;="&/1
@r4085
NGTGTCATCAAGCTCCCCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCC
+
!A*&.?)3-$C7$F*A#)!6<%=;383H*-%/(,5/:%B;=90(H20/-%578&940;8#/8+0-0!)@#;!..#>@A0B#HB:)>;8%51$:7.!F3:A6>?'$/6("A)50G5;9+H#&4H3$/-"3%@1"F9<C?E
@r4086
AAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACAAAGCCTTGCTCAAATTGGNATCAG
+
#:33HAG-83(((%>@.01'$6G$?#CE@(1&F/:FA$43,$=-::C&G%$C<G9%&)">;A63B3:
@r4087
AGCNCANANNCGGCTCNCCNGAANGNNANTNGNNCNNCCNNNTAGNGANNGNGANNCCCNACANGNNAACGCAG
+
!"$""#!$$$#$$#!!"!#"$"$!!"#$"$###!!!"$!##"!""!#$$!!##!"$#"""$#$"!!#$!#$#!$
@r4088
TGGTACTCCGCTGTACTGGATAGCNGCCAGTATCAATATCAAACCNGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCNATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAAT
+
**'%'*$!+")+"'$&&"$('!&*%)"*#(%"#!)'"*'(*+'$'$#$%"&$#)#$%+"!$"!!#($&#'")$''(!%)!+&"%$((*+!%&!&&&)&%*)#"+(")*)&(%("%#$$)$!$+*#(+'%')&%+'$('&('"'&'#&+&('')"**"#%!"+%&'&("'*!"+++"
@r4089
TGAAGCGGNAAAAAGTGCCGCAGNCGCAGAGTCCTCAAAAAACGCGGCGGCCA
+
'+%!($('%"(+$%&(!$+&)%(!*"+*#!"+)&*(%'*)&&%%!++(!*&%*
@r4090
NTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAA
+
*/-#A++E5DB8A,&'!7D'=2"/9'=56**>D&?84<*3"716G-,&+;C<F)>DHE7=)4$%):<G*-4;1-82*:44>#6>0:.4%@EA(!ED?-H9>9!+4G(-%<FF4,DC?8!3!?</">>3$9?;
@r4091
AGCCGCCCAGGTCTTTTTCTGCTCTGACATNACGTTANTCAGCGCCAGCGGATTATCGCC
+
))$7D1.'3<"-17D/"H+;5*H%08D8H<H5!B+:9H2BE$G*D!7+',3?3-;:8</*
@r4092
GGCAGGTGNTNCTGNTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGNCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACCTCCAGCCGTAAGCTGGTTGCGTGGGAT
+
&%&)!&'$#)%$!(!++*"*)'%'*"%(&($"%)$!+)%*)"&*$"!*)$)'"+!("!!)$#')+"#%(%!!%)#$*)%$)!$*!+'(!$+!%'$'!'+(!'&*$"*+#'$$(#&!*!*&&%&&%%&!+$'(%"+"**%#)+%&$$(&$&)'&())+%%"&#&$$&((!+#"%"(!!#)"#(#*!#))#'!)*+&%&&!$!)*
@r4093
CCCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGA
+
%#>AED1H#61>/,,,@C&-BF;(9C-!?A!=2+8A=4F!,A:AF:#22-""#9EC,F&$)3C1<"7@$!1G#@2
@r4094
ATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCAACGTTTTTTGAT
+
D7D24<E?<0E=0=8>+;A2A$/4=50.;D0,08'38?;G%7-&A%)'&A&&#6==,C,)$<5+$63"./:G4"3'(GG6F?1
@r4095
ACCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGAAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATG
+
%B&;D5*B/4>.2:;.6)+!8:<?703=+%729@H*?>64D;<((//FCH4=2=&4/+B<GA/4D4"9#4GD4=$8@?3<8$;:#,B:(,:!10A9$2>=)"*<,!3"%,F!<8*49*725A:9'<4*1H'?+/
@r4096
NAGCTCCAAGCTCANCAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCCTCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGA
+
(2(!B=#D66/=4-@3,;C(CAH)$C/;B>8C*/!!C91EB&&C7"-D:>H9+>?F5?12DG:HC6*?7GF,8"(+=,2-89H#(1FG,2A%4>@-=,"7=+B59+C8;HE1(6&;<?5/1@)GE,<"39437B!A!:GG+15!;6)!8'45B-F588"'4(2F@7+>%:+2!%F@8@@6$.3<9CHC*)8)%'4&2A$>>@@#&>4,H6=72C67@C)87EC,
@r4097
CGGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCA
+
5DG7!,=9,3F#@33,36@7D.A!&4ED4G)3/*910=F9766.&H1
@r4098
CATTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCT
+
?+&".:7>5!(F!>%A@=#%'5$%927D5<H=;C<%+1EH/>9/;
@r4099
ACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAANGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGAT
+
F5+B)B,/=&71F$85"6@>)&@&+B352'G@E+<%#6'*'E.&1*6BD73/0*<*'368'*-BG$/+*>);%C$C0&/98$7.77'>F!2&C.?77<HD900A!$7>)137;8#?$7.B,+"GGC%6!>9+$&9?.:6,4?D8D9$)0A,F-17A?,F5BE@6
@r4100
TGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTG
+
0@96HD!!*%A=.'44=5%,#=@::8*B!&>F9*H1#'=;2=:3%?"=G">6(!B1+-7(
@r4101
GTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGGTGAAACGACATACATTGCAAGGAGTTTATAAA
+
BHE6/:-''&B#?5#5-5:+#ED20CE':-;=;(=%-*+)D?1/8"<$B@1H.,;7!A=1&E1ED%2F*B"H14-@#G/H
@r4102
ATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTNCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGNCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGANCTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTA
+
(+#(&#+#!)'!$"#'%#(&"&*&'&#$&))')+)%)!(#%#+!(*''*&+!%$#!'%%**("'&(+&($)(#!)(#"&%(+'!!$"(")('""(&+$*%)")'$#'%)&()$"&%#'#+)!%))*#!#*($!!!'#")!$&!'!#")&*+&+'*&#+)+'#"#%#)')!')"%#((!'%)$&!(!)"'*$#)'###*("#&'#))#)&&"$!"%%$&)')
@r4103
CCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATG
+
*>,>,(1/<<D!2<4EC91G&?*%F4C6**@.C#B3#/?4>8%/)17F!'EFA?1@&/%5!D1>H16B+C9=B1B*B76+;2D
@r4104
NTGAAGTANTATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCAGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAANATGCTTAATAGCANCATTT
+
!+6!<?<;&$)7+(A.HC8D!D8HF?-2')*1'(2672??376)F&9++$C5B9=2F1A<"&'.1#/>4/*75F50.)8@H1<CH3>G;8B!/BH;&DDD)B<*(+6<$=F'+;B(BH0!+(D;/(#(
@r4105
ATAACCATGTGGTGATTAACACCGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCTTGATGAAATTCAGACACAGATG
+
++%<:A/-,0(=.H3&=A;DD.<7??;=3+5,65:%$?H*FG)>2"=9758F-'1'600))FB$.*H-02<@'C!:A!=<<DH6B#@<//4;C7?)<!:$@*H!1D(+B:-A>"<4
@r4106
TGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTAT
+
&9<!>$$6*1845G(8CHF&8A8>0&<?F)-07$15C#44><$C#GF*A'C12'";;241;)&E#4D?#%7.&909/6"B+;
@r4107
CTAAANAAGGAAAANTCNNNTAAATCGANNGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGA
+
'*$*(!!)&)$$"%&(#""$())&$"%&"##+!**'$%%*(%*()$+(#*$"!("%#"*)))#"*((*+#+&%)!$**&)&!)+&(%!+
@r4108
CTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATT
+
@+%0%G':>9%&'&&,<@4*<31EB/DE6E.$1&1"02%6E))=H<!9,@=6H0,H0"C?&=G::F$%3E>EB*G@38/HHF@68$E$<68$672=HG+79:08>*,5EF/2/".*%&#6%"7;,&,>8+D'"H6,>52<8/@:(!
@r4109
GACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCAT
+
"$=3=F04F8%8@)45B3?GC"#44*39F;G/<AA8D#%?!G4H%!B25/),6
@r4110
GTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTCCCGGACTNGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGNGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTNGCCCTGCGGCTGGTAATGGGTAAAGGTTTCGTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTNAACGGCATCAGATGCCGGGTTACCTGCAGCCAGNGGTGCCGGTGCCCCCTGCATCA
+
$>4>%-9(FB("2"$%0533B%9A@E<@#)""3#4C::&EF!>#:/@CA54AB-A8"5(5#B25?0(<?.@E&3."#D?-5;G>8'!42".9;FA='!:,E+02-?$!F"401.7(D''F<%<G6*9C(045G3)1AD8#&F.0,BH+F"G6!8?#,0;3-27ED9%&398=:>5AD$:?A98/2*2*:66A"9E71?"<E-!?@8@9>A%D)#+!.1GC)2?23/A+GAB0"B,0/H3&'!H>E&,0>=8BA=81:73@9"2,<D)94$F<<>/;)C:+>:BA$<825-2/0;)840HE%'58<;6@-'%.B42?#)=G)6B,6&D$$2E19"D#839(7"'8'@E-B,0F+&0D(<4;4+&!B@C5)$)&
@r4111
TCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCNGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGNCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACG
+
+84827)!HB6;1%/",</'+HG/7H*!A9.:=5?84A;6=$"*:<H;"DD-:-!&%>,1<0>$9':=E&@C3:7!;B*=6-A*7=$'E#F/+:8B<;%.%#2A$.*1D%&C1H%.:,&B77FB1'/A3BF.D4.=5"20:E<3=%&"B!9"C%H12)<B#29C!"5@$7!%
@r4112
AAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTNATGATTTTGCTGCNTCTTTTGAGGCCACCG
+
:?(!=%=%&CGH<'6.E2>.1+$<7)!D%:D)=DF9-6!!'4H90")@A#F33D4C)1%6@#1/$:B"'
@r4113
GTTGNGAGAGACAAATNCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATAATGACAAATACAGCAAAAATACTCAACTTCGGNAGAGG
+
%&))&%'"*'(+!+)!#&+"%%%#+!&$#!#)"*)%)'(+&!$'!!'&"+&)%$""++$()"+)(&#"*%&&$&)%+%""+#!##+(+%(#*(#*%#%'&%*
@r4114
CGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGG
+
=05"!;E?E'/+)G"?('3(;5.8*BA6)@:H!H9<C,33A':-='75
@r4115
TTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAA
+
>6=H)@)?::668)>:/?&-7EE)'H7$<F=%DC4.'3?A1C;6HE>90H5A0'18"6>=D$26?805=?$;@D9!"(=H54/7.;(2'@)%/:5!.&'%4F(">@:28.B$%A8G5C45<&6'5C/8%;-'(1!%8";
@r4116
AATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATANTCATTATCACTTTACGGGTCCTTTCNGGTGATCCGACAGGTTAC
+
42>/B"20=E4C-<3)%2@>-0>27B1"?".$*51'-(-&".:AB@4'1,6>/"??1)&B9#1#645$=?:#$+/71/8"2"*>:(,7!(6@9G:"1721:%5
@r4117
GGAAATAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGNCAAGTTTGCGAGGGTNATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCAGAACCATGATTTCTGGTTTTCNGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCC
+
-<5:E>7=%1:9)*+#83@:.6"=%:/;+;1*%0!G3GAF6"B,!ADAA=*.A+1-3;5>3==%G09)+E=?&EE7((F.FH:=6F&@31=06@A>%C7G14C3@'%)=%>7A.@<=0C1HA)<D%%#-H"9$/?/!,G>6)&)(-$&%2$!/"9.=:-/%,$(2)+=6GD&F3C(*>5)<1+"#1(
@r4118
AATCNAACATTGATTCAGGTACAGGGAGANGGCGCATNAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGNTGAGCGACTCACCACGGGC
+
'%"$!&+%"'(%#$"&!"'$++#*'*))&$'*%!)'&*$$*!$((*(*#"#)!#'(+""*'#)%"#($!)+#%%%%#)+!$"*((!)$)("!%#!)%##)+%!
@r4119
TAGATAGCCACGGACTTCGTAGCNACTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATA
+
):,4=BA9C/1!>5((?7?.B,;DGCC(H"#7!G'51-1,.3,F&8182C3,,<0F0-A=H
@r4120
GCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATT
+
1)(+.G1F*A;?7*1A9H"AC7$4>'?A(7>?C2.1,FC7AE*10H+-?3%$=<4H@,':%39->A3"002=E'E6?-)*,.6"%0:
@r4121
AATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCANAT
+
9&2#%'H$H8/%*,1.H%+#(;*('06+D!&%!/?E3DC@=2*H'-<<8.1%)@$E0'1AC??D*%?:7&=DD*1<E:/@G+-7
@r4122
NNGANACNGNAAANCCCGCGNNTAGANACNNNANNCCCNAANNACGCNTTNGCNNATTGTATNNAAANCNNNGNTGNNNA
+
!"$#""$#$!#$$"#$""!$$$"$$""""#!"$!!!"!!##!!##!!!$"""$!""$#$$!!"$$"!$#""##!$""!""
@r4123
CGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATG
+
A?50$E%7:!3>=H!G@G5FF22877/03??"9%=&?<,:41H;8<(6'H#*7.734!.A$.C<0C.'/711+B(H7F8956D/0>#6<F*;#"@/0;9-&@0?B?#!(,B8$4E2
@r4124
CTTTCCCCCTCCGGCGTGCTTACCAGGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAA
+
?(#,6-%"#).?F<(/4B87#6@C)#E/A=)9,=.'A!!00CDG,3)E-<6C*/4982-F9*71*%<C7@('E/:'6*B//2C4;A7!C2G;?%/6E##%1<4@-?','=
@r4125
ACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGACCCGGCGACTCTGGGAACTATGAATTACA
+
/+#A"H5*HBE,=B4!.4.-D:=(6,3&43<H6';?F027)4.$=>B)6*=#@G"5-9H0:&:4+.E.!>5<H.#F#E)&#"6B8++*C(EA!(072G.1#5ABF5(=4%?'6?$!A?%:;D)%1B"6/C$&F9A,6H*:<%G
@r4126
NCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGTNTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTC
+
!=3CH5/8<*%E"C@.#'%.5&F!1.8&8C,*-")9G2G0>3GHH$@)6*@!7C:=%6&>E7;)8%..4.5BB94045?D?;?B%5A)!@1#=(%0<+,3</G0,(90-.D:11.='5!DC2&!('%B>5@H/+46E+9A#748-$A.#-FA*B-HB;AD6?$GH7-.-,>9(.&D
@r4127
GGCCNCCAGTGCCGTTGCGGNGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCATCCNCCACGTCTGNCTCCACCGCGGACACGAAAGCGTCANAGGCCG
+
1DF$*<B1#;:8#597C++G36'1<7#C3(8'909?CH""$B?!@60H?6,&##96379<!?/&37&*:6=1,H,%*!7H(#+-#%>>3'.&94C.37>BC?5F##B
@r4128
CGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGG
+
>6'+$D99@A'F;72)A8$85@3E!:,5:8.4A+7C:-!?HA="8<-*<*
@r4129
ACGACTTCCTCACACCCAGCATGCATACCTTTCCGCCATAACTGTANTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAANACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATNTATGCATTAATAGACTATATCGTTGGTATAAACAGTGC
+
D33B)=,;8=:/D1<9='4=#.+-E'&?EA:>+.7@E4E+!B'..:849(>:"F>=2G:729E>'H5/3;$()::2=?7&1*$$@87;@9$D?F5>5-4>5;&/11'F!(6)>;<#ECH!,>>?#1H?(5G$4):$C/A$!(H(1@5D=;(;C!>&&3"G?*4<)F'25D>=.">H7'B)'=G(6C"D39:2681:GG1"%87$>@C##-<3>"#<!D!!&@3
@r4130
TGGTTNACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCAC
+
+"!#"#$""&)&%'"(*(#!'$"%$+)++$+$'%""%#!#''"+'*+!""!("("#
@r4131
NTCNGCNANANNGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCA
+
"&(#*(#)&*#"+'$'(%+$#)#&'!*(*!"&"($('*(!(+$'$)%#%
@r4132
TCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTNAAAAGAAAGGAAACGACAGGTGCTGAAAGCGCGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACA
+
(FH/3,#@.:?9@0GF/<-#51>D:!,H>%373<@DB=4&;15"(!4',*(>A:+D8H&B5#B7?0+#,H4.!D+G4!C;8--B:G?(*&7<5%."#EC7@?42%/8@BF8&E.!+$(.@""6
@r4133
CCGAATTCTCACNGGCCCCAAGGTATTCAAGAACATCTGC
+
%-(5*)%B4*&;A:/''?*/C56(5D4)A5!H)#?%<+3/
@r4134
GTGTCCCCTTNNNNCGNNGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCNCCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCNAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCG
+
&$%#$)*$"'%"$!#&)*+'*$!%+%!%!$#&(&"$$)*#!&"()"!$#!"#)&'*+#"%%)'+#)'*%#)(*$!+*(!+#"''()#&*##*&(!'#%('!"('*$#+$')%#)&**!&$+(!(""(+)()$'&#!"&'####'#!'(*+%!'("#&'&**()%(('%)$((+)!*$+*"#%&*%!$+$*&$$")(#)*#"+&#&&()#%
@r4135
GGTACNCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGNAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTTGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGG
+
%*%(*#+8BE+===G0&'.0=36E0/#AF(/(#(F2-569%!-!F58"@>8:$+,&G:@-&DG-C0>)?(1,>2E-(D6-1*<=.C9B.2-9D21A+?4#8H:$=G"@:F8"2"B6*$B$&$F6/AE)+G4#-'>:$G'8(2>6HH<DD)D414D3F@FE@2/8,,1809)$8,B$'&69.@F6,+9H4G$,05'--D#81
@r4136
TGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATT
+
F)D1-6>0=-9<@6-#A5(=/B;+H%463<G1!!#%&-$<&AG-(6%G9=@5(*/::6B:D/@4,8+44:!79/AE15;$)C8
@r4137
NTACCATGCTGCGATCTTCTGCCATCGACGGACGTCCCAC
+
$D138!#$$0:*1%.B:H.9#"<:")C0-,1>9+&FDC5'
@r4138
GGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAGATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTC
+
7>@+$!?<&:2%;<"&,1+!/,%1>)FG8)H;26.''<5="D7)#!B!199'C2$18.%:0+$&&.*9#B<E4$A6H#.0?24?)<-&+)AB:#$"*3G=41G-7>1='5/<;FF737:2
@r4139
ATTCTCAACTTAGCCAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCCGAATGAAT
+
B-A0EHE),-3H<8+-A)$78'&*DE.*-&+7F!"7/$>FG!G6G:+5(#!D?A?.C.*$;$-5%%0B#!C'>=3<B
@r4140
CGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTG
+
457"!CA-AA<>0)4EA(FG?D:5=@54>,G!>-)&'%":H7!>."?$(:-+D>&?H190D+2&0!9@3#.3=@0;@@)75"(1G1F3>!G'=>-D8+?6A!)E9,A3,H4(&0;*G0?4-F%,=4!$3/
@r4141
ANCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTNGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGA
+
-'9%)"4G7!16C,B6'6&FB>;9"D@-E(D?(H'99#(/"C5HB5+$71=(#)3&(26B@#@9?@"C"@E88A%!>D#G*$40>::B5>D4(1((07<<<6C$@!4#$
@r4142
CGGTGATAAATTACCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGNACGCACTGACCACCATGAAGGTGACGCTCTTAAAAAGTAAGCCCTGCAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGAATCCGGATTAGCTGCCAATGGGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCA
+
69B:G";?&FEAF4DCH/3A5<2G2!4'5)1/6,$2+6"F4E&@&7<<G/D.06;:'=,!%,>,2<0%:6/2-@+49,B-7=#3D<B"2668@#%<"%!4E7!##9,14$)1?0>/581#(:*8H!!594405C5=0.F(#78>5'&!C,D)0D55==6BE<1/:/8G"9#)$E*0D%56%2*;/EH0$)*$#2%8'/<="%?42):,5!!E,++BHF2H?B1!%/;6+,C<5&'1:F);D#?70:3H&)(%2F7
@r4143
CAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTC
+
B@0@A03.<8(>6?)@;*"H4);:.=5=:&2CDD7-)3EG/7.H<BC.5
@r4144
GGGGGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCAT
+
/F!EB9G9C5H"&>!B/G.9B#G7B!9;?12*0>B2B@B99?:321H';*'&<$3;+'"636.6HD!)>5)5:0DD9<!6:.E4+3!#,#G;32/H#'!?<+223)*?<=,%=/A<B'@F.79%76&>5H97ACC9%7/*+$F=12/>=09=9A7,=3H
@r4145
GACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGC
+
&.0:0H8/7;!3C>B.>!FA($B'0<.>#B0F<D:G5C=E.AH(!7E3.;*2"8:94-;'.5?&#
@r4146
GCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGC
+
...;@$H-</.;>2F28-B;;DAD5(:CF1??-HD(A?6F1B'=@=:3;A'?%48@7:=8*1,7=57E0,=@C?!2
@r4147
GCCCTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCATTTGCATACATTCAACCCATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGA
+
#@;-8)'&!.<*<</:<E<6?'-6DD>DE.%CH4.1=*(3$GGC>:*=>((G/D#-E#GF&88+$E(*1D"*'?*35(1H4!?7$">":G4*/:A3%C(%8>4++172G4@;B#23>C;$E+5;*'@1B%%C.EA,0<
@r4148
TCTGNCAGGGCGGCANAAACGTCCGAGACGAATGCCAGGTCATCT
+
$=,1(+;1?BH"<;@336)E)-A(=,#HG92<-ACB%:+)$6D;%
@r4149
TTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAANGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTAT
+
=@C1,1B%.;F42=@&-*%,0@:2!49A;)'05F,+==B2GDB+<E#!>%D#+BD($<8#6#G9,@H88BCH7D/B38@=.,=*)/8E9?,F2?4+2>23&27=,&&F"9&4>D+*>6.A+<+A;@87#&!;3C?@,=08
@r4150
GGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGNCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAG
+
=&%F48&C294/A></+5)*C%,030)9!3G;9A6=CD&)%"1=!)4B,(>CDGD2<6"957:0C**/=3997&EA:094897+%%>%2(G@3@"=:>>7*HB"+
@r4151
NAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCC
+
!4-B>."%$F=?GD-?G7:')4/-B+H75*1-9'B8%&'7A$(G;AG.6"$.B2+E9:2&3001C+*G.
@r4152
GAAACGCTTCTTCAGAAGCCTNAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACNTGAATAACAG
+
28,%/+>:8G:18G7?,G,+,F>/=60*"/*D@96A#>*=E':*"(,)EA.*,-GC&E'>,9C7$#B37-?;>+46'8(EH1>"<3<)'5;@/$F&/"#(F.E$'3?-
@r4153
GCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCNGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGA
+
CC:E0442"'4D'&;6H/&9EA0A95/E3<,F/*$<,A%);->A:A1*5E)B7A,F7*6%!78-88??'5B1@D=4.5*,435*5C8;;GB49D%&<DE7+'>/+E.?)E(F89@)@230/C.@?.E#8814!@+9&.?@/D
@r4154
ATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGNTAAAATTTTCCGGTAACGGACCGAGTTCANAAANAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGGCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGG
+
25H?",&>7/&7(;=9.G6'94<>!"0>%#D.;7<<620FH63(((GAFDFD!04A449*;H8$G<>8,4&6-?<@7G7.;#?*6A)FA3@+7+#$''8:/6%>"&,?;6,,4G@H$@(4-E:5D6G91+/#?#.6DAEG"23)E@%!&'B5A,F;EE6#492*%#0';2'@<<1.5G7(?4%C?8',1D&8DD$!-4CH5<#3688GFC8>*@,C3E*#.4B%3@5EF9FF6:,?1
@r4155
GCAGACCGCGTGCCTGAGTGTTCCCNAGCACCATCGTGTTGTCCGGCAGGAAGTTCTT
+
;@<,A-$'27,3)@"48.,BAB9$C919:=4"9?"*A6->&AG*!9!/D=5G60?'/=
@r4156
TTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTAT
+
BH4'B6'#5DA/F/9%:CD)E:CD*)$0E8:'0A(55*&%*:*).+51F2::1A?$7>*,B0$H%'9D'47#F6&CE6+>2FG8;0;)
@r4157
CTCACCGCACCGNTAACATCGCGTCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTNGCTCGTAC
+
&5)@E>2;11F7H49B;DF3<>4!6)$2H,?B>=>7.C1.?5*)-'#3))E9E'-()=$6AA4;E:GG=<G?,+&-'3C$-;9#@+.B>82!.E"A>9-CC-"4%6'5<2!B",9E%'<
@r4158
GGCTAACCAGGCTCGCCGACTCTNCACTATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCG
+
93G#=%7'"01.*C'79*!;E:A*%F57@?+2#3D*G)D'FGDCD960:38.<A)>8./A3()'#&D+EH@>DE;8&08H$1,C5"69F7D2*)':H%5439),*8.77)2H38,<DD:
@r4159
GCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTNCAGGCCGTGNGGTTGATATTGCCAAAACAGAGCTGTGGGGGA
+
8F7+?5*$;/C)9?99$;'71H7:=!190HE**.(6FBG;$0+.B/<9:C#H-975HD246C4'D2%9'&1*A7D(C%?B?75"'B'A24B56@&@31
@r4160
ACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTNACTCCGCCTGTTCTGCC
+
<5!,<0'G.E:C-(C*=F;#E&@!-/-G!F23>@/H@EB0'D%4,F"FE3=**3H*)"D#&@H&4GH)H5FH#49#D<4"1#+@?'G0;<G1/F(:6:-*D7-'2+5&*354@8*$4F=/:78.3FDC:.;=>0/CBF>C@EC(:4G;"<:E=,@?G/#6:#$F@83G@@6,BC,6,?=D,'78F=3<7H%$?EFF&?>::B3>?4B
@r4161
AAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACC
+
!+(!&%('(#)!($+$$$'#+%)&+++'##($"!%$!#(%!(#$%(!+!*'%)*('+*))
@r4162
ACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAG
+
.11%%7E+'5?38H2-:@/H677*)%'/;-:$($-"+"446H&0>:A@$*G)&(?@'G9&3021&&;330?#?E%8=5GD#6E##=;?-<>=$<!-$+8G-6'*E*0<<C!A3
@r4163
CTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTNT
+
=6<B7&?A)61-9,-=,71>,(?A5<B.HE#0@H"80C&@B=.%"5'*;H8D@-6852A+F5%0(*;.D.G&,74B%*(G2-!*4GB$B9G2-AD*?;4&5;
@r4164
ATGGCGGCTTTATACTGCCCGACGGAAATCCCNGCTTTCTGNGCAGCCAGCGCCTGTCGGCNCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCA
+
AG.>HA>G"8!H%:@/7H)>:9>6&8/4=;=$-<2B33&C1#<G!'4&19'5-%&7G73<?3+7:1C!94,/C1*@;/)H)@<7-$0H;C+3):7#/+C8-6G1G#'#*30</%D%7"$73H&6<@#866716=.#@8!*.2EH$@&9294<-E5$F)4%3H&:",
@r4165
ACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTNAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGCGGCTGGGTCAGC
+
<9'23*G7"=D799+@?/B(@&60E><%<E3CG>435;/#GF@@2EE"#B!2+76%"+'9::2D9D3="1445H90CD.:/G'679/"G7;7($103(?@-55%!;>A"$G,#0:G9C;H2?A8636@9=#
@r4166
CATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCA
+
@?2%44%%-"GH"F&A@3.+.?(>,%:1G$!(B#$'+1#<?66"+G.D<1&*@H#5DB/&H!:"@?<%$)!-&H3+;B%6)
@r4167
NCAACTGTTTCAGCCACTGCTCCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGA
+
!;!G$4A5;/*3D'+;&-1,:&7&;8<(:#4%')CGG:<=B#7,HGH3'1&@D=A,B4C*:9/</
@r4168
TAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGA
+
..!?F*"+<*+9,3@;*(*G<'(:C#%$.C94$3"0A(7+.06./*%'$3D3'F%#56>CG,&A'4?*--BD'D5&&-5;?)4;;'--=?&,'"53(G1D&+&-5CAA297/%73,;7E
@r4169
TNANAAACNTNGCNTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAAAAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATT
+
$"&'&*&)"("&++)!()(&(!(#!&$)"$'(#"$#'$+(!(+#%)')$%&!$!)#*"*)")&#!)))$'""#)$*$&'&"##(+(')('('$%%&+$!!+(%!*))+&(#
@r4170
AATGGCTGTACCGCCTTACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGNAGC
+
%F/7=F?&'22-0022"&CC28>.>!15$C4G,%D:'9";<+&+/&9--64$,(.7*<(1?0>;()1/G71;B06F:#44?<><HD7(<F-:)7.H>E"C!<,!15D<'$2BE4G/%;0!9)FG.):93;E10#,0?
@r4171
TCGGTATNNTTCNGCCGTGACGCTTCGGTATCGCTCTGCTG
+
%'($%!($!!#)*(***+$'#+**)'++"($#%'(!"!+%&
@r4172
NNCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTNCTTAATATCTTCAACTGAAGCTTTAGAGCGATT
+
#+#('*%+"&)$*$$$+)+'*#$#'#+)%#'&"*%(!(+$$%)*"$&'$%"%+%"&$#+('(%%"!*($%((%(+)+*'%(#&'"$(%+#
@r4173
NCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACNCATAACCAATTGTATTTATTG
+
#B?4G.GA3$?('!$71F>21&9/30/,'5B;($,F&H#*B&(/1(/+42G/;!E4/
@r4174
GGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCANCCCAGAAAACAATGAATATTTTTTCTCTGA
+
G15.61,&$7+C<@!,4;&9/C(D#("F'4>262%6)*"";-/&@-*?DD4+@%;<C$$!-,1B"&5=<C@"&)?FB%$-G#-?G
@r4175
TTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGA
+
=>#.#C0)@)5H3FE6E37-2"&9<G,9<<?F-+*:70GGH?-0C+2@/%/7H%
@r4176
TGTGNGGGTGATGGCTTCCCTGGGGTTCNCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCNATGGCCGGAGTGG
+
=C#)?6A%A=D?C;4&6AF?BD!A,B&"B'7H2-<AF;-DE<,2F*;3G/6@0FH2"#HC*%>?&;#.D"E<%G08+(=);*,4EGC+@E9CB6B?*.E#)?'7F4'$!"72#!2F?%=%:+@#9=DA0"CG99(&B5B4$B)+&!$,C0(+<5.9883/%EH#&B4A*7!4.
@r4177
TACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCNCCCGAATAAGCCTCAAGCAGCATATTNGA
+
&@2'D@10/"B,/-45>C>4#9D*$-88801%%13/F.;3(?57A/E+=/B%:E2B/D*-%C2D('5.8.+#;E%23>F
@r4178
NGNAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGNTTCAGCGCCCTGAAGGACCGCCAT
+
#6B-F-7D.$1G=>>/'5+F)G7%,D4H;0&$B$3-5*14=B8"9A&@7%3**(+&';<&-327588'&(E6
@r4179
GGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCGCGGTCG
+
H:7>1ED"4/A9!5>+8C+.7/CF:,6*EF;!F-;E42.C6%!9B(7BC3(//>@?
@r4180
GGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTC
+
'.H)G@41H6*-)'$1#@6E8G,!-%@A2:0ACB,1;28F",6(3*'$A.HF6"A1*@H%($B2(//0)44.0E,=C45@B+?6$BG4.C<F7+2!.*</$%?"6F7*2"?21<&?((8%?50><E/D17>(D:4*87C=+<AC"HH.
@r4181
CGTCAAAGCTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAACGCAGGCCTTCACGCTTCATACGCG
+
B(.(055!G!);0;($DD80D@0F3)D.#DC<HF<D:/"9/E(?.!7/""-F76F13(#B8.#&@=H<$?HC
@r4182
GNCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGANCNCGTC
+
(!+'*#$(')**#)"**%%$('&!$'*"$&&()##*$(***()&$
@r4183
ACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTGNTCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATATTTA
+
@D!4!%.'8>52>9=770=23!5<:6*"37*:HD'+C8:FF'=2#4$.A:!=/*?H!(B'/$/=?D>1/0-?@;:-6:G4=A/A*G>"@'6$/)&9(A(D-!-<-?A61,D&%15.
@r4184
CGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGN
+
0817FB2""3)2;%'-3;%B9,//3*-/87+('!:DAD>;$-.?.';;2&/'515=HF1)?&'
@r4185
AGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCNAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGNTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTT
+
F(:#2B'6>,&,4E,"G/B7=$G@B-&F3EF<$7$9#5>@EC82"7<(A:F8#(2$0.3)1<%"&AA30;B4%$"(.8.?E/='DA78=#:(/56=>5?=0(<;GB<:)9)8H(*6CG.<;*&D6H<;0>G>=0;C0/&54#@,-'!+4F-G=?FBC#5'GD0$$(7>'*DCE"+)"':F9H-3'*C7F/<3"-"+E>;'%F.8&*3E0;9'?H);D;!44-7/EF&F4E=-2=E:C75C=#B%G-'>:2&4#C&
@r4186
CAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGA
+
*,E7$7114.3C70DG5&<+&B9"=E+%F$:>4B8A/6C@8=C"B
@r4187
CGACACGCTNCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTG
+
$>@,!!>8):!B/*A-$E.F3$;8C=4963&***C@&5,+$CE,;$'!5*8A%8;2G(#,$22?B
@r4188
TTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACAT
+
G+8=56HF6&<54762?='4&96&GG/GH&(DG)>(3#;=-!E229$9$:A(;9&&$HH!.+9@G1B<!!G941
@r4189
TGCCGGATCATTCTTTACCGCCGGAGCCACCCTTACAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACC
+
2>"/9.%<!--!-?)C,H9&*C54?48?=%',2*28#@*">;+54#0-8!,,CC<.3:=B4.;-'05(%:D/2
@r4190
TCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATNGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCGCCCATACGCTGTATTCAGCAA
+
)6,5G66,5C%C656?.BH#/%*4)#A8BCA:3D5C?/.>A2A3%"E"05;28@@F!21#8H<B:B--A''87.;0*8B7:$8$+:B+!A>;.B=:,?H94*/*F#>AG2=D?&FE(CE!:D/09)49EF/)"5@(!(E;$?+%@/!%$)3#6GADDG*6E'3%C!
@r4191
ATATCATCAAAGCCATGAACAAAGCAGCNGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATGTCGAACAGTCAGGTTAACAGGCTGCGGCATTTTNTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCG
+
(6>7=(5!)/*H01=A39.4&/56-B"E!F;8:"#&+D1(!B4B:/H/:,.';@8BC>!2?)<.5?>!9#38F!1,E>E6.BH=&FH"EH74A@EA-6>)!(-2'EG<4C<(B.9/@GB*"4.:2B8,,"@$G')B"/+497H6D2F3B7$
@r4192
AGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCA
+
6B@A>0'%DC<C)=,B(;.,40>!,%"=++5"3'B3!"A6@<:AH00%1$1GH62=6DB
@r4193
TGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTTTGGAACCAAGATA
+
>7876&#%#5<82#?-/*"3.#647)#,=,?)3>1-4%.755H,.=#GB8+;,C=)0B$H
@r4194
NTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTT
+
!3&68,2;#2!+*+H=BB1/7.B4/B?C<H78/;@1-=&2"5F<7/&F,4+('*.;-C=8.(4=EB+7)"D@-2B50C2H/9#5;)&F42)(7F.$3$66265(@F#D
@r4195
GCGATGATGCGGAAGGTTACCTNGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTG
+
D1-6"=>5H4#9H60?E6B437%,C%==9H!$$7HG-),*-#06B.'3E@/<!&:)97**:*!54G%(..7D(&+A">B#2(8E;72.'
@r4196
NNNTGNAAGTGNCGCAANANCGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAACCCCATGACACAGACAGAATCAGCGATTCTGGCGCACG
+
#"$$&'##%$"#*(!('('!'('+)&"#%)##''(*%(!!%*"&(&$!*)*#(+)"+))!*%)*+**"#%%%+&&#)$)'#!)"*%(!+#(!'$&$&!('%!+"("$%
@r4197
GCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGNAACACGTCGTTCATGAATATCTGGTTGCCCTGCGC
+
>1'36$D&@//85D3;362=,!GF6=848&E+;.:449%(&E+F;G;??.=@D$:B0C!95CCB>3G+C"F>,H2A2/>7.B-H%E/E(6&)4?'8:"0!1E(C*A>7@B&7,5B,8)6!G#.GBE<,/$.A$)C-CB*(34!:6E7;;-C#
@r4198
GGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCG
+
,@".>5;&%!796@5>&G1.0&)*@4#H338?2;.AAD/5
@r4199
NCTGACGNGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAGCTTTGTAATCTCG
+
!</@B&2E!9/!+%:+#FD5)'C4.29C6!&&"/;%7=&'%2(6)B74":-'F?0EB=
@r4200
ATACGGCGTGGNTTTAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCNCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATAACGCCGCAATTTACTG
+
%#""&%#'"($!)"%+%+$*"!*+$#&'(%+"'$'%#+&%($$'&)**+$()%+'&+)&($!%%)"+'&!&$!$&*+"'*+((*&(#)(#*''%%#)*!)(&+(%"$!*"('&+("($+!$(##'#)"#*+"*'!#+&%!'$*)""&*$$#'!&"+&)&*+!($"&'"(''%#'#'+)'%&"##+!#
@r4201
TGCGTGGGGGCAGCAGGGCNATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAANGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTNGTACGGCGNTGTACTGGATAGCCGCCAGTA
+
#)((#(($('(%+$&!$'!*'%+*#%&"+!+'!"*%)')**##+*(($)"+**%$&'%&#*%%'(&'#((!*#++$("!$(+")!$)$"+#%%*#+%!$!*!*"*!+$*$"+#&"*'!'(%##%$(('"&($*'*)**$#)')*'+&""*$$#"%*'"%*)"#&+!"$%)&$)$!'$)"(#$%'%+!$&)$"++)&*+)")"+#!+*&(+&)!'"!%%$%+*"%''$)"%'!)%)%())!')
@r4202
TGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACA
+
F04?,1FCE;?,FDG:.*02?1,"A6F;B$@!D$0#C?7C?9".)<)"(1D@..2<2H0-+6:7>A#-(&49.%"2@7B6%D15GC1HH.C
@r4203
GCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGATTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTNT
+
98.56C?+42'53<8:0AB79AF33B38-7+:&E2HE@%7A4;5FC()-,*>>D'G%H3-G@C-C@7H1=(@&6A:#;$,3#93=&C"8@,GC?6*?-$;(:$3C/0@.2*/;+0B+?H%!=0%->E,88C'F--A(C3)&4:A07E*F&9
@r4204
TAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGT
+
<)-?;0C&;?A(BE=8*:67F#$%G)B&1"2@5/F&((0?#D+04)
@r4205
ATAAGTNGCAGATNAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGC
+
2!5.3!7&F=!,(+@@%0'>2&":>+C,/@G4F?$<0>7<?G%**<F8:$')12H%7
@r4206
TACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGAT
+
>;4'896?)@6.E'2>1AC@1<!.6+,1BBG5!:&EEF$D0-=20@,.0A'),*9<*05>,#-G!3&)')9(+%8CE,A7),"&=43G2".@5<
@r4207
TCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTNGCGGTCTCTTTCTCTGNTGAAGGCGTTTACGGCTTGTTGGGCT
+
?F/8@/F/+!827+FB=-D!=56<$78?:C@7C(;H2!8>#E"$(//BA":8?C*);;.''C;:)&!%)A2=H(G#"9),?5;A(662%G
@r4208
TGGCAAAAGCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAAGCCCAATGNTTCGTCATCTGCGAGGCTNTTCTTAATATCT
+
F%-$"<09!(GE7+>67(F1,)(#?A>'<:?66;35&"BF-<"EH&6(2@*!>&"=?3;CAAAG%@4+7F(#7;>28'0."BF*%'
@r4209
NTGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTA
+
"-$3C935:</$8-10F@7?*55(".(,'07E350/%(GB
@r4210
CTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGACAGCACCCGGANTTCCGGAAAC
+
+F(8<<$D,!F(34&1!1(%B40>B(:!:1(9CG2-:4H+:,HA<6+'7?#>7A,<79,E>H#0
@r4211
TTTTTNCTTCGNTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATNTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTG
+
63B23#1;@5H>1+95+B5!6$FE)0+,A1,"A9#H=7=B-8<#BE#%C0).C</C9'*:+A4:G1?;'%3&:5FG+$/378610)B92B3(E)/D
@r4212
CCTGTTCAAACTCTGCGCTGAACTNAACACGNAGCNTACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGTCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTN
+
+)'$&'&"*+"+'++&%$!"$%#"("#*+#+(++#+(%((+&!)*$*$""&&!##%%"!')&&)*"'+%#&$+!'+%&'$#"+*%!%('*&!!#(*+'!*#"*%%)&%("'++"+$"*('%)%+*)'&&"('
@r4213
CTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCG
+
41?H(=!-;'53->5!F.$FA:8:8FA382:@--E'6D75(7/B5C1(",,AC5!;<>A-@/8+CDB&)71=A6;$)B--3AD#8@G!3'5C3F7@A(10"":=#
@r4214
TCGATAACTCTGNTGAATGGCTCTCCATTCCATTCCCCTGTGNCTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTGGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCNAGGATTGATATGTAATATTGGG
+
1#-##"A2G5%ED%DH>:@B$7/"@B,4D242.@53.?</5<0HFH)796;1CA:B0(,B4A(.C$25&%7D'B<C//;$-2BH>.,2B6)B@E86+%$@A/31&68:#E5EBH$,/@4E9F#=//>24HF1DB)>1!9.HE?
@r4215
GCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGNGGATCACCC
+
'5B&">@#-;A+0*6$0,7G!C29+<?38*-96.+C7.'$;#'B-&102F84.-E/>;$FA=F
@r4216
CGTTTAGTGCATTTGATCCTTTTACTCCNCCTAAAGAACAACCTGAGCCAGCAAAAGGTACACAATACTTTTATANTGGACTCAAG
+
0,%3!*7H%5)<=3=DGD:F9%(+&EB./C3H9&<+E9!+H5?->A1;);64$E8A%#+;3=5F-F!).65G%A@$$6$6-0"9$E
@r4217
GTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATC
+
EG#6:#8E));:@'"6*>?5$4(8&F<%$1G/%1188$+B8=7=5<$A$(H4@A7@$!"(&&+)7925BD<98#A@E!8$#:
@r4218
CTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAACGTGAAACCCGGTATGGATGTGGCTT
+
4("F?+;,9$=>5DHBDE';2(6<@5'438"EE49>@*4(>B(&0@H5#!).=&<.<-H+4>+-40
@r4219
TCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAG
+
8C=7:*A(H.$HG51<$.*34<6+7"@"<#B?5?)!3F#"8(
@r4220
CCTGCAAGNTGCGTGGCCACGTCGNTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTC
+
)5:;"'"B34B,B*--@)%,H<8EF+E"B57115*7E>>E=0E'7/0>B57C>&%6)A#8$61=+'$<F@<812D/C9*3)9?502CB'4)"B@9*10<<E(5/H=:.=0*0*F1B,G9:8<
@r4221
AGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGT
+
<7.'+)%:*2(,C="DC':-&-(6,C/'!AD=*00#<@"'#7&DAC72?D=3?"(!7H>
@r4222
TTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGG
+
)6"#D*A92)<>5(EE6'8*8;'H"F:"/:D-G9-%2BH9:E(9@48H"A,D:C<@/A:FF1?=.DB)4CCE%>/<00/H?)4>F0,0.@.61+B83H=%3)2>#BG<'<(.EF4>
@r4223
GCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTNCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACTGTCAGACGGAGCAGGAAACNCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCNCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATA
+
1-=!))-6$72.A.8:+E5!H42"?2BGG4%6AG!.@EHAFB<3:'=D@):D8,229$CH(D4;=1':2)'3G%H@/?;C7)?07BD36C9E88(%&)A3-ECCBEFC+AG,C3</%%88;E!!?-G.0=H@3;*E/&?%H!+:B9B'+A&B+.#7&'68>7;273)>"D$%9>H)$6%-/":4HBD)2E0";5H?;5=(1(E*0%A1#2"8/&8A,@"$F=5(A-.3E0&",3!.D5411&.3?:%
@r4224
CGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAANCNTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGNCTGATTGCCGNAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTNGCCACCGCCAGCGAGGTGGCCCCCACCA
+
?>+A=&+4)CEFG-"1+%F0&3@8/C;1BF=4F86G614A@7<G-E&36+<@@H'-5-F&2&.C+<'B94//93B.$@-/1>5G)F-0!F99%1+6%(F=9#FFG.*F.B!@0--59>8+7D5/F136"6:+5F.!=//0G0/:.@='4-@H9AH23;G4#!&+*2+<A>%,82C":,::E/8<%C'E$$9')"E7;5>D%!:"2<;9,94,51#2G5
@r4225
AGTNGACAGNCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAATTCCTCCAGTCTGCTGGCGT
+
#'"'#(*')#+$%*&+(!$(%*&%%&$+%###%)(&*$$+(+#*!!#')%!*!"!'(()'!)"''#%()$*&%+&+#*
@r4226
NATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTAC
+
/A-D3528H(9A!!8;*/G75#,;=4;H(2<)>1)$17:<@>$2'04$
@r4227
CNNGTGTCTGTGGGATATGCTGACCCATCCGCGCNACNGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCG
+
'$"%+"%)(*'&!$"%*+*('"$"$'+&)&%#+$!!(")#)(!)!+""$)&&"")(+*"**"&"%*%%*)#)%*"*$%)***+)'!#"(*#&#+!'!"+%"%#)&)$*$#+%'+#$&+$)&#"%&$)#$!&#%"!*##"#**+!+("!%+)+($$$!+#"#%!%'"+)")*)*')&%'!+*$%*"'(!)%*(*%!(+(%$$"!#*#(*('+)$"*"))*$')+(#%$)+"!'
@r4228
CGGACATTACGAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGG
+
9:%+>92$-$2G<;'4A:>>GF2H3*1C>C?H%:8$/'###A"/,:F$18#H28";6
@r4229
ACGGCGNGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAG
+
F70-66F@@;99)/@58"@D5@%)>C5B@A"-=79!)-A5EE(,7!<H;(!'*<5F(&7;G,*H&F/@/<*-6#)4@;0&0.)E?!$G<,0=2G)2,$G-=;:E7@8+</-/@,$D2E05%GF=!:#>D0/$&#A*@B6B5!?#37"-E,H;H"0-$136,'1$;.E>*@>$0A3B+9>#0?;;F??&@23%C:B,+'F0D4.:+@?=?$=.?62$GD=A!#+4;-@&21#7:)>:&6C*BHE5$E4&
@r4230
CTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTT
+
1#EH?5*-AH73C*"6(6H'9G5*0?95+1>7(A<':5:=6/0%/=/A)
@r4231
NTGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTNAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAACAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCT
+
$&+$#%%"&$)#)''#'%%$%##*('$*)+!'+$*'+*'%)&'+!!%*)#!$$"#&($+&)!$&$'("&#')(**$"$#**(%''(*&'$+%(!%($%"'%(("$!!'&'%#$*&+##)+)))*#%)%$#'+&*&&&!%"$*%%*
@r4232
GGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAG
+
)G=A-()%0A4!2'!;:./'@D.8;.".+)D0*&$@#&58(&,.9A/@(4(%7#9"9.2F-&6?96'-B<D?AHC0A+>GDB902-H+%.G3<>?%7%?@&18&4:
@r4233
GGAATGATTGGTATCACCAACCCAGAAAACAATGAATNTTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAGAGGNATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATT
+
)H,G9,H9&=(0/(&2>"'GA9@3GC+3#5?>A4#(H+6;+8&68025<+@H<F@1(>@;)&09A-*%7E$H'&H,*%/+AE;.*79G?C&4"0=;#15=9$;'5=;+GED(*(=6E<55+>'7.
@r4234
TATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCNC
+
4+)=?C#7-+AFH?A:9:1)=,56G'0F(.F3D%)%=@2&1C
@r4235
TNCTGNGAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCNGTTTTCGATCAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACNTCCTGTAATGGTTGCTGNTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGNGCCCCCGTGTTATTCGTCGATTTGGTGNCGTAATCGAAACTGTCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTNGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTCCGACTTAATTCCATCCTGTTCCTGAGACANTACAGCACGACCGCTGGNGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACNGCAAGGTTTGGGTNGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGANATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGTCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGT
+
%$($'!!+%#+$)##+*""%***%%"+())(((!(""%*%*"(*+%*+)+$'%'++(*+!+##')'"!('")(+#')'!+)*$"!*)%*+)!!'%+&)%"$+*)&'*'&+%+%!$"!!!(#%$))*')+$'#+"))%)"+()*!"('"&&"!))$)%(%'*$#%#"$'%!&$$%+*##$"""'&!&&'#%)'+%"))())"&#+"+#%%!"%!%&"'+%*+(*"#'!%)%#!"#"!*($!!#+*%)%+()$'%&"%+!((!#('&*'+)#&&"'%%&&&&(("#(!*"(('(+&)"#*#+$)!)()#'"('"*)))"+'%$*#$)&!"+*)")(#!%('**$)%&)(&'*'"!$&)*"&!"%'%%+"++*#!#*"(*(!*&**%*!*&)*)*''%(#!!)*$$$%"$'&!!'%#%(+!$+#$&%!$))$'%+$%!(()+)')'#+()!)++"&)#&&$$%"&)&")(%"+&%+$&+$)(+))'!(&##&#)()(*)%(#"%&&#&&!+&'"*%'#'(*+(*%(#((+($'"#)'#"$"")$$'(!&*$&"!((*+!&'"#)#($%*&#"&%'"%&#(*"!'%""!&+&()))#")#$&$()(+')*!"(!%&(#$'#'"!$+(&*"))*&$+&%'%$&)&)))&&+*""##+(&+%%'%*+&"'*%'*&$+"('#**+!''"#)%'''''#&((')$$#($!"!%*$#'+$*&*(&#%"$$
@r4236
CCGTCAGGCTGCTGATCCCAAGCTNGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCG
+
:?A6*G?2F*?80=*E<&2,:/)94F$4@>+8'*%8D*9)'6=CAE%6.'*/),=0E0GH(8
@r4237
GAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATT
+
)H1=#6(=31H5'&.4?%@;'G.E5HG/:(BD-!.@,(D0&#A%>,%<!<@;/(7D
@r4238
TTNCNNNGTNTCCGNTGGAANACGGGNNNNNATCANAGTGGAGNCNTNNCTGNCGTGAGAC
+
$##$$$##!"#!$$$###!!!$#$$"$!$!$#""#$#"$"##"$!$$$!$##$"$!#$"$"
@r4239
GNNATTTNCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCT
+
%")1.B?D?>A(50EA>B9D71:HH7A46H%C?848!<GFBB#"&",DA;:026C#*'"G(,,
@r4240
TCCNACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTTCAGGCACTG
+
&"$"255/!G184'%'A)EFG-*%'7"(+))<1D5;'A:/G?445BD7C$;B;H9.4;!#<;2
@r4241
CCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTNGCAATGCCCGCGCAGACGATCTGGTACGCA
+
>%"G?,$$2D$A+G$<6F:C&H<H+-5<57@GH09'*A+6(<(7CH$2CG127C5CA0)&,D3<0:#+6%667=H+
@r4242
GCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTNTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACT
+
2(B1>($@0*56*"B"H2;E:#&+@D$@03**,AB89&ED7#)5D8='A4);D?H<B;$($A&>H(1<1:HGD?E0!,7-;74&C4B/HB-0*8.1(!
@r4243
CCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAG
+
H14G47.>CC402."-B<3$<D@,490<+,?2FA7=;/?(H+GB232;$>F:%)%"F3$A*:@!?21&"7>(>+C,-"<,;3F!H7$>*2H$2?'CF/(2;3$AC4C*$?6D8E?&H!CAB+,&@'&H;D76E'$:E)2
@r4244
GTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAA
+
96<!A)*,?%CD0#:=FF*?7"4?9?;8AHE*$+9>'7"34:A*3G
@r4245
NNNGNTCANCACANCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCNTTCATTAAGGGCNGCGCACAAAACCANAGATTGCTCTTCTGTAAGGTTNTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAANTCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAA
+
#)"'$'#%+$&$(!)"'%**++*++"%#+)!'#!(&"&'#&#*+((()+$(%+#&**"!'!&%#+'%)'##&*'&&%+%$*&+*(%+)&$(+*"$*)##%)$!&)%$!"'&%#%*(%%!)&%%$*&+'#)#)'##($+"#$#")$"!%&'%+)+'%&##))'#"!'*)$&'*%((*%#"&**)(#'*%'(!&'%('"*%'$&'*&+($)')$"%+*")*!#+))%(*
@r4246
TTNTNGGCNATCTTCTNTGCCCNCCAGTGTGAGGGCGATTTT
+
&'!)*(*'"+*+()!%!(''&$#(&!((&%((+$%%(!++"&
@r4247
TACACGCAGGAAAAAACCGCCANCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGTATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCC
+
'6;<&,'*;GA1;=!"+#7A01<.=9:$&+G2,'/G&%-<7;,C?D4(D(C-+AF)D<F9$.E4G(+5;H$:'H0<'0B1$4508<1.2CD43HF%.C,0G3
@r4248
AGCANGTGCNGNTGGCNNTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAGTGGGGGGTC
+
$(&*(()%"("!#%&&'!++($'*#+$+"%$'&*%'*("&'%#!'&+))&'&!$$+#$"%&(#$*%
@r4249
AACCGAAGCGGCTAAAGCCNAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTAAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGC
+
%:F:6)5+;$2-H"<.A=5;74"#0&>H.C,D!3E*E47&H?(+";;.5;,'?*BE/+9EF8B3AE.DB-EGD-;9B4)!2DH>."96!=&4D6'=:6H0?2-<@"BH
@r4250
NATTNTNNTNATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAA
+
&#%!!%#$*+%*+)&+)&&'#''"("%(!''!%'&&%%%#**'+)))!("
@r4251
ATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCT
+
G>A$G?,(6!&)3-E"+,0?/7>#9"CB<AHG+CB%/G"@CG"H/7
@r4252
CGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAG
+
F464<8$$48F5H!A-9;-1"6G9.!;1G8=:.E#8;&&.#%"E/&$%*DH&DH44HE>A?#H5:--$:?127.'><B#=.=B(<>5A"$C(B?!'9A;@1*2E6,B@"%5(#!D/4/G312!>4$5EA@7C&-)C&9;.A
@r4253
GCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCNGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGNGCAAAACTCAGCTCACCGTCGAA
+
A'F3:23#<<<9:C!(FF2!%?3,F5*0$DG3>F&D-8E25$C%@5FGF4"7$-H1<&AC-.".FH<04G$;%$>1=$?%G,)6A(4*!5'"C76.C?'=58@>/7)H;!2('/DHFC!!8G+D&!!%80;EA%H>+7&3#35")
@r4254
CACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATT
+
3H@,106;1'!:5FEH8D8$++)-8),:F(58+671:';#+G+9"G2C10)?'1
@r4255
GCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCACCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACA
+
3F>33""2H34'+""B2E;E8;4=(8%->9E8E*>79CB=.,F:05,7G0G6H@=:&<<F/-/6&H9@2<":%@<7,>G))?='<24AD2B5<&&A"-HF/64FE8'#8C8%<-$!<>)&(>H<3?/FC("+9B*="248D94&9@!2A&5%A%%0$D'06/'!951;4*36<(+0
@r4256
CCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGA
+
E35.#'B/<E..B'%D?+D,C?*E4$0./":<:/5/<+>'4.B!=)>G
@r4257
AAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTGAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATA
+
:E2CF*@4D3(8)*1'(E,<A:+9C>?A$!+;7*'%2>$++E&<"4D;F/"5!21-B83%:*.F53@,FB=8$.6E)*(@G/,!G$10ED!"><1C<E8>"4),C31"9A2!C*9->1:>@!)#D%=H8CG-/#%%>):%A,A6?9
@r4258
AACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACG
+
(.F>6&.2A",!8G?*$#%;$8H(7<8=+;<A%!EB)$H8H/A$/?"<*H%(6($0*B#*130B5F<AB).?F685"9'2+27H8/E+B5!'?->C,6?6.*0&FA414:6"'9()B92%0=#+:$#7,.&/5B*:D6+4@G+@F"$B)+;A,&A'A,4G&F=&'F3'=8::=@8#4E"),&B%
@r4259
TAAATTAATAGGCATCACCGAAAATTCAGGATAATGTNCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATNTTTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTGGCGGGTTTGTTTTTATCTCGGNGATTATTTTCATAAAGCTTTTCTAATTT
+
88-&'##'93**$G;*,)C%E8*6!31,9*16/$@?E5D:?C&>?001<)4@,03;7.D)00:,#&>>'<>"@=7CG<BG2!F#)5:&?55*HA775=(7)6HH!9G")>"3!'<8:&C3$$;?,8D8A#D*.(8&(/A!D<>3/&!%0CB$'BH#/F-#-*5<**13F(H>5)4:A==+?")6F"=
@r4260
TTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTC
+
9).#+FC2%(A@=EF1$=>9.C:$=,>E)C#</$8CF#;*G"0)7/:7/>A62@97:3590<'"86(#,,11%(,*(8$'@79D(9A0<AE'.39!@5905A6?:
@r4261
AAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTNGCTGGGTGAAC
+
%&'4:>%7#8B<&G@#4D+8BE$#&HG3:%/*"/:G902.0.>#/-9>E#&,-*=
@r4262
CCCGGACGAACCTCTGTAACACACTCCGACCANGCTGATGCCCAGCGCNTGTTTCTTAATCACCATAACCTGCACANCGCTGNCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAA
+
$+)!'&&&+)%)*"(#!*(&$)'***%('++'"$%''%+')*'+"*%##("+'**#*#"!))&%*!#!)'""$)!%#**&&&*)#'!&$#)'$()"+%'$*!$*&+&!*)!&'"#&&)+($)$&**!)*)!#""$
@r4263
AATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACC
+
<.8%HD.$$A'1<%:!EB6D=0.B?5@4=>05B&1@@7)5'.1),$F%F8E,0")D+
@r4264
TTTTATGACAATATCCAGAAATATCTGCTTCGNATGAGCTCTGGACATGAAATTGTTTT
+
0+=#E67*'(!''$E&+5#AA+;G)-38'3F<&*H429$-4'"5-3)!+"91$D!A?1D
@r4265
AGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGC
+
4::7FGE59E>$5-5<HG=4>8.&2A+)B$!4&,5/69<-/H9C(-@F0H1!@/!5F4/>%7F""6F%/*3>FF'!)65)71/3E7&(4=-G8H,9'*<HC3%;5>;+';5/A&F9H/7+@C036=@?CFB!$>$
@r4266
CAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTAATCGGGAAGT
+
&2%2/:7F/-G!;9<3BD'!*(90DC=B";85H3A2@@')7*:A.+0;>-E49EBCE
@r4267
ATCCTATCTGAGCATTATAATTTTTTAGAATGGTTTCATAAGAACGCTCTGAATCAAAGCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAG
+
=EF,!4%)4--&F/=8D)@@+5+3D8>0'30#9(F'0F,C!:,0(C#5F?,*:C4,0>02(G>'%!/0*-4HA?74=&B"E'!6#E6'"8>&0?2$1,<H>/;!8B/8/?(=3.,%%@(.A7
@r4268
CGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCNTTAATATCTTCAGGAA
+
4!FH!@D@)1!'69H22-;7G",%=B"!)7/F&#62!C1?=-H!=G#!FD@$=@);%5,
@r4269
TTATTGGTATGCGGTAAAACCGANCTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGANGTATCGAT
+
D212927?B')4(@=A2E/C2+(39(6/&C@;G73CE+,1@&3#$7AD@!@.250%@CD9DH?!F3<.+.+'.AF:3@"
@r4270
ATTGGTGAAGGTGACGCATATATTCCGCCTCATACNGGTCTGCCTGCAAACAGTACCGATATTGAACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGA
+
1'CAF@F+*;!A"*H>:2=HH2)@(8@>.%0A<*6.7)4@D>F,'E%C$!:?H"3):9'.6G(>6#C)AE7)GFG?+7<0$-((.:/*8A?-<00H9!?F2$#?1!<-"H
@r4271
TATTTATCCCTTGCGGTGATAGATTTAACNTTTGAGCACAAAAAAGAAATCATTAACACAAGAGCAGC
+
.8F3&,18,5A49A,5+>/'$.@60#8,#)/BF2"))@A#()#=0;9=,,3@7!F"".&:A<)+.3=H
@r4272
GTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGNGATATGTCAAGCCGAAGCATGAAG
+
74FG>?'@D-+<A1(F2.=,&!%E.;F4@(03&)!!(G;;?67F%8$0?B(7C=7?.?.51<-%8/98>!0CA%*(+G#H-0B!'%%DEE+
@r4273
TATAAANAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCC
+
:76;#F92(?%467"E(D(B.H:GF%3#3#B$8/H.A508@D<425"/A%G")-<'-*.1+:4?-0#3=5B<!("+,;.66/,"BAH2D1>G'<
@r4274
ATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAANCCG
+
-DH>9A,-EG6HB%9*<($>1D41C@'C6&6E(*31HB<=50.-8D@/B+0
@r4275
TTTGCCTTAGTATATCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTAGATAGCCTNTTGTTTGTCGTTCTGGC
+
70$:'5,7.)4!GG8)HAH;(A>A96?@-B@1;()(C%1;:97"=+@,510G8/<C7@=(4>-??B)B-HB*:C:<1:6>F99<':(03(8;$6<=@9(6'4;@@'
@r4276
TCNTATNATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAAAAACACCTTATGTNCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAA
+
D*13<"$E9H38#%&).7@+HB!6!(9D+%&HD.B@.6@*HBC3?-&?9@FD@8'""BG#33><@@A<B16+=7&06!;(G<4!=G6@-!7<%G-%76C;!+F=D>-B%8!2C#5B!33/#G,,C@6*5'4=E>;:,D
@r4277
NGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCNCTTCGGTTTATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCANCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCG
+
$8-59F..GA/E''!$DH(HB$529@,"0*)10,54,E@6D**2+0*A6+F-&;7&&'(:F#'A:1'$;#')&#+=<9$14(8<F++?HC+$E@5%.&D<*<&-BH0/=%#?6D-*2;"@C0C995-$D8930:E?/-!-)7?#H,)<3986::GE;>.G/9"0AA9='>"??'B,!/!E4<CE,-4H$B/:1G.1",2:-8#$860,<$84!D&#BFE%69+%CBF60C'A4=&!9*(?A!5=D"/=AB@:>3"A0?=HG%,A6<6FE:0D+02B7AC@@>5@B??!&&#7$A6%:@(;7<$A$-?E,9*34)F-
@r4278
AATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTNATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACNGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCT
+
8E";GC'3$<C00.,";H92%GG+G*$,1F%0F-G:A-C!0-0C@<G:F&<36&*&FB(.H@"$;%..;>G)9#%8C!6/,/$0)$6B>6B2">)-G9HA6:=G*EG.HG0F%=E523<<20.@;6>('3=8=E,A5/H>C85@,66'6'1)<@*??2+$88<>"97'#A+#BG:>%FB+@@79(H$(?.C=$D</--D#<$''6A5;ECD-<$6%219CHB,*.+)+D>#*HE#D;15*GB%,5E!388:).H<F!C(F!%53A*.C%%/.',)9+".:4!C+6&E7:B>A=8,,;C#=&6/FF60!E.D8?6"/
@r4279
CGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATNAACCTCTGGNGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAG
+
@(5>$0$E#+&;0+H&EF72<78*H=@F'4G5GEHH=#F2?(=+</B=5*$C!73>*9D93$G,@;D5<0(66)3+9#$B=,:.F>"4F!!@H?E=/(3G64@G*D?<E:&=-2D*38%.#8!!;(F@G13<?8A:,D6A
@r4280
TAAGCATATGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAA
+
7@%?1A=*G:?>9:B=@HFF2@A#-+6E5&8G5*F=@<A!.<8E(.;%.#@*5=@1A#?+3:+<7H2'@C*7&'!'>#0G>@0;;;@/-:926B;6FF(C'?1#:E!*>H<>B!G1G>=<"--=<<B)9D>..D+8/6'@!F%@(;@,<-7'F/8.4@1+$B0=DC
@r4281
CATTCCAGNCATGCTCGTTNAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAA
+
-<@,,0+G%)#*!+2C/*+01+A(G#.?@B#)E*2=2%'1;<&0,F-+CF79,=/!;+5''$H!E?B48',A#.;CD!=9./!@"E@.@<HB0G8&5G"1/88BA.2DE6<(*F'<?AA#$DH!!:;9-=+@,?D=#/*+47@,2DBB5;?"</E':F,6"#F3>G*(&:<$F)C!><2
@r4282
GCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTNCTGTTGATATTTCTA
+
?,8"<59!4(H):-1&4$2"E77**:;$:8703:>;G(&;2)E.,EE$06:
@r4283
TGNGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGGCATCACA
+
(#!<5(4G?B+*&;3!14!9C*='/A6783(/&,'!GD0?7@#D#+!)46#)9FH%BD+1*..194#4"#%
@r4284
TGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAA
+
>0(7E@1&-B?&/%6'#H9''*@-CDA+,+8<5B*<!")"7(%'A8D-C*G),&5DAF!)4%:D3+/51<"(@/G$C>'=!++C*DFA>:E#2@C
@r4285
CCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCNTCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTG
+
0?14(6*G1'?!=$3!B>'8:(!=D8!54"AEC%F?'.,!7H.>=@(C@(10D/68G478B*>(BAA.9H(-',A:=#D1)0:0()*F*/F-'EC"+GAB"0#;G0%*C,4@7F19$8#=-?$9*:1.G;/B+)D?2/&%+=?B8?;E)G#848*!!'%7B@*/H)9E2516"6(6G"'$9($=3*
@r4286
TCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGTTGAACGTGTCGGCATGGATTCTG
+
<2&,?%;"C0;!//+2?G*@GB($//9%G&=G;8:3+8<4-/&+-26-A:G7,=#+$2=@.%H3BC!/A&01)AC!0C
@r4287
GNTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACATT
+
5<,0'?>4C2%8'75>/.../?,8(5:5*1,!FC7?D%'5,#"A<(35(172H##=(FE
@r4288
NAGCGANGNTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCNGGTATGGCTGAACCGGTAGGGGATCTGGTTGTTGATTTGA
+
"")*$*)*+)+(&'&+&"&(+("+&*(*#(($(*)!'"!'$$&$'$&+!"'!%$"'"&)%(!#$!+"**%"#""#+($"*&"%+((%+*$&+*%!&*!%%&!)$#((%#+#%$#(+((('!#"%(+"$"&!*)&"$!'*#!*!&&#)*$!!)*$()!(#$("+$()#"'"+)''()'(!(!%$**&()$"$&)"!)#$%$)%#!'))+&**')(!**'&%%%
@r4289
TCGTCAAAGGGATAATCNGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATG
+
C''05:B8!"/@27/C1+.)!&#E<"-CB*A@*5@G..C='A-1145:?/G'E<8;,">G$37
@r4290
NAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCG
+
%GH'!+H%(#(G>H*<&C'1C"86G<ECC!'3H$670>$+E4>/!1+04;28-6#$(.
@r4291
AGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGA
+
'+#'!+'&'(!#)%'"#)'$*%$#$+'&#+!!!+%)(!&#"%&!)$""!(!#*&+%(!&+#++&)!(*'#$&!("'#)&$'#(&++)'&*("!*"")!!&")%!)%($')$&!%)%&%$"#('()"'!+
@r4292
ACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACAT
+
E5&09$+,#G(!"F42C@B5A:%<,1+!H0":9()+%2F,*.#;-$F0*%;E.$E$(<B*"?%0*AEG,:
@r4293
GGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTNANTCCAGCCGGGCTANGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCC
+
0*,&$9$$1/F9E/?@,-F=)E+E.E(17;3<+F:C4+:)(9?')H2/D!%?;!)'!0/-G!:2%:?C&#GC-#?&)C!:<C*A1EC,+9E=E5"DE.>D0<**E!.+B%H)A(G3BDD"-'4-@(A!?B%%E32+C1#3-GA;=-22F=+#&</
@r4294
CCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTG
+
';@0H@@4EH>.;;FH4B8(@5),#1?:,"EB**@(A-0??#>6$C8)
@r4295
GCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGA
+
4+((@D+G!62.*??B<&#-)52/A5!@G3DA,,';$#A1H"
@r4296
CGGTAGTNAAGATTGTGCCTGTCTTTTAACCACATCAGGCNCGG
+
+E$:1-$E0)!,;%"E!(?%)95"GG3>*A*.?G5F"G>6,=#.
@r4297
AGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCA
+
F0"!E*>!-;B'B%9>77-:HH-)>.,<D:':+#9#14:?+4$H8.372
@r4298
TTTTTCGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATG
+
,H532?D)'447*,/CC<)!(2@-*/#;EG/#1<E'%)1'2((GE6;7
@r4299
NNGNAANTTNTANNANNNNNANATANGGCTNNAACNANNCNNTTNGNNNGGNANGNTANNNNTNTACNNNAANNNGGNNNNNTTNNGGANNNANNNGNTCANNANANNNCNNNCGTNA
+
#!$"""#"#!#$$##"""!!!"#!"!!!#$$"!"!"!!"$!#$""$#"##"!#$!!"##""#!""$$!"$$$!!#!$""$""$"#!$"!$!!#$!!!!"#!###$"$$!!#!###!""
@r4300
NCANNTCAGCNTGTCTTNCTCCGTGAGAGCTATCCCTTCACCAC
+
#!'&!*($'$"'!&))$!!*+#+#&"'+'%!'"(*&)$"'+*)#
@r4301
ATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGC
+
4E9-(H,?$;+0F768(344,.%#G<,)H'";)*0B<:($%:H7&B>H."%B=1.2GE?)1.,H/2
@r4302
TGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCNTC
+
=&-6:DG#-&?4>,9F+0'1;<24;93*7G<'A)C+!52A25<-/B7:78A!$27E#'#">;?:=39%+B@/!H!E'D,"G-0
@r4303
TTTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCTATATACCGCCAATACCCGTTTCATC
+
*/C%<?5;<F4E;A6!HFFF9(#F!4A#A75%DE(#2F&*GD55+$%8'3+8:6*C37*59DC*3&#(#=",->C,?-G#
@r4304
AGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGNTGTGAGAGCTGTCG
+
3H8GA;,@E-;'9+&,@HFH!=.B'H)>;B.<B+3?"EEH!4>>.A/*>A$&=?<CF%7G0H06)7=/09,3CF-4*&*5!C&1/9BB<)F,?&)$BCH($G>8<#'.&"=&*@1;*,G&9>0H167
@r4305
AAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAAT
+
F,;7?8(D*491>6C)!)2!F0(/'5,$5:C07(D.,+D7>H.GF?>G5-A0/.:$"F%!*>5F,%2&E;5HG%F>$AA213.11'&6<?;8B'58'92H4CEB32%;,))=-7&134EG4662G(88E>&'/;>4A(FF*%8CG99E)?5705E8<<)<>"<'F@7#7+#B%$%7512:7D*7!9-%$G!
@r4306
GTGTTCCGGCATGTTGTTGGCGATNCGACGCATCTGCTCACGGTCA
+
!1.59$3'$;4@=@1@-?,D5'(#$658HH:8>=#9B+G#:8F($+
@r4307
CATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGATGAGATGCGGCACACAGCGGAACNTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCC
+
/<"2=!9'#,/*0!7)HB!'()-$"2:2C3AC6'9?#-)4"6AA2.H*5125)$>+1"&+%E,DD55BB;C=:2=;$?3519#=,"#)'0,="H:7!'-H6>7D55@0.32C>GD.35#%87HA/%/95$>7)A5HH9
@r4308
NNNNACGCCNTNAGGGNGANGANCCCCATGTTCAGGGNGCTTGCCGGTGCGATCANCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATNCCTGGTATCAGGGCAACTCCACCCTGTCCGATTTCAACAAAACGC
+
(""*#$'('%'"*'%#!&($((++*)&&+$('!""))!!$'&*$!)(+'(#+&!(#"*""&#)('#"%$(%+"(*+"''!%$&)*'&!)+')++%%)"'+$$$'!(&!%)$(+'&#+%&%+!'##'!+%)#$#%+'#')"'*)!(+&(+'%&)!(+)
@r4309
NCGCCTTGTTTTTCTATNGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTT
+
!>@17=1<''!*55F=C;AC9AC0%17@%.9/"3,2$+G/8*G8-5=/"C=EB=1<*5(=(.
@r4310
GATACCAATCATTCCATTCAAAATTGTTGTNTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTANCCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCG
+
FG!GH#0D=$<9"9==G:,*4%BC8,$48$?&45(H-C=F'+1=2E7*.C=&4$(":<&GG+EGE-@+:=/"?'*159?>61"D$A;+;1ED5&+/%6@%"%?4A?+=D+AG$G91C3@?":%::+#
@r4311
CGTGACACCGGATATGTTGGTANTCCCCTCTGTGTCCAGCACCGGCG
+
*%H."BE#*%0&)'9AE6+9G=,/!70!1#1!E%=H1#HC$<./58H
@r4312
ATACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTACAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACNTAAGCGAAACAA
+
"79.*?+("4;;&-H3,<@35@F=)9)'#69DH);:#-=1D;$.%#E(D))=>18-A-FB<61%)5&<1;2,5*=7A-C=@6-"D16&G=A(.%2>C3B3?7;3!-E&7B4E9'/4*GG+(!3E*?"<*1**DEH$$73=.G=(>&F.8#>2;FFB7"=E.)-'DC!=-7A@%7A0">6&(9C@*"?6<8;A"A6+F0F&<'?9$0D!#1>,6->HH&-@)H=(+6C8<7/F9*+C:5&G%*9*,;!(67!52H<%FC'6*1:H414..1:824AHA>*,*7C2--H(ED3;#7:8?./0*@92;C6
@r4313
NCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCC
+
$0%(-:F+F.%+%C7.BD:":,5)GC@"1(%F$B7D$3)-'9
@r4314
CGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTT
+
G:A%C4%%-*!"/#:**9G;:C8@0(FC49!%@9.15#2A?D;8,3&G*8%*1!>3%C=>%C@G<C!-0,3G0*#<+?G!F/"AB0H,)-9?('G%=82:C0!0&.C%A5-?#3<"-<4&1?,)G1"2'=#BD3*@HC-AEF<"!5:'=!$72%A+D%<!((.H1%/
@r4315
CATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGA
+
,."8%H54%%0*.11/&A5#A<1&%)'%1*9+/8#?266-9%+"=6G'!/8D!E.
@r4316
CAGCGTCTCATNTTTATGCGNCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCC
+
+%EF?>%/2(@,+12#9E>9%C0F=:+H,7<,828DG5H34:2<13/2-6A(;B&=!A>?&3/,
@r4317
CAACAACCAGATCGCCTACCGGTTCAGCCAGACCGGACTCCTCCTGCGATCCCTTCT
+
F=$24'6)!)E@6$*+)%"@>&#/A;'(0?E@G=5#2B3;43>51*7A(7,A)(?((
@r4318
AACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCGGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCCAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCA
+
%0'C)-2":A>F78+*53!(-403!(=C+FC+./&/6BHF5-!;"'89;H1,/5+:+="A8>9+E?.C+>CD(#H'F?0137F&9"28GAC"0?-7"B0/=6B455@)A?81&A!.=7E<G+&;E-(%<+,'+18C!C9/:A7HFACH*HE,ABH4EA=&@9+'>9,/&!>!9=EF7'#<1BH!-F$%H!7H@C,@?A(F'18-,3;@*:%46!%$H),&20
@r4319
GTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCA
+
7!%<+'*?)'@!G+D-H84';D&3?0F;255"2(>+29#4-@-F!7E-'@1(;21,5=98B6E-D<.%;;748:#>B'9>7"!;4.330:)H#?FH<627-(2<:B51CEH75&@%7($(*%1"G15&HG=@6=*="F/*144E$?-<0;219H7$F5*+*$G!%-/!&$B5$B;5;</-+8%
@r4320
TTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCG
+
"H9*8@D'8/C/0B%=-)5F-C3:7#)'8H*;5#(A,C')=389F<@5D4!58+HH-1<8*16%@#
@r4321
CTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTACATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTT
+
$*</A*<-*)H)"B@BD3B4+57$C.-$E#.23H4DD=<(&AA,!B&8;15E@%?@H>:*?E0#H7C>EA7#A!"G2:?03-.(3,.8F?#(H251-12B+&(694@42B(@C>H48'5AH>#-)A)55>7.4'.3-%F&'1)$B3EB@9$-4("D@.?402#<"!)
@r4322
ACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTT
+
/2-+(HB%21/5;="E,)H7F=#>F4-)55%<&0902;7>!7$*&$09D"#%@<7@7!(6;6+=3-@#.>5"6(3%G;#92/5>$9
@r4323
AAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGG
+
@-.'):FA0E7++2GD/C?H5<;*;>BH!,?<GD:2;6CH&H7%;46$!0+<%D*A,44!;0),-B"<,EFEA=DA:$CEF$H$FA8AF>436.!D4!
@r4324
CTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCA
+
-%/4++,@!%3))C1,D8/8H"C7@51*6>/"CAC??+>'&C-
@r4325
CNTTGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCC
+
#!"!%")$'*+&$*%*&"&"#**###)*##+#+'%$&$"#"%'#!#)'%&!%+%)$!)*'&"+'*&!%('##(+!!$"&'(%+&#$)%(%&+&#!%+!"'#%
@r4326
TTTCTGCCGTGCTTGAGGGCAAANACACCATGACCGGTGAAGCCTTCGNTCCGGTTGAGGTGGATANGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACNTATGANTCCCGACCCGGACGATATCGAAGCCTACGNGCTGAACGCCA
+
0.$?.&3C;DF9H=F2E$.@@<3)53)3399C4)+<B";;5+:9:+7$F7#5FD;#=+$53C7??E8A9?*@36D>$'2.(C;%*5$(1BE-C7?,3/8HE5/6'H&65.="(B28A*/G,=&9*10CFA!&.<%#((@E<.>F0-3(41>5E6G#)8?0,B%0=395B''#9"1=6):/
@r4327
TGACCCCTCCAGTTATATCTCTGCGAGCATAATGCCNGCGTCATCCGCNAGCAGGAGCCGGATTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACNTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTATAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCATCGCCCGTTCCTGACCGTGTGGCTTACCTCACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAG
+
:G7@0!*A(&2!@$-'D7G:$48731F*D$@#<?:32'/97%67D;@:(1B/8$10"46*4&H6++#/+8#9;*9=+DE6:57-H2(C-"-8%8ADG8(=E@+C1;&BCC4&:;!.8-*B"0'A.*,<#;B2?/=!<8G$.<5*&197=#:.G-<+;7*.%56$*:@@H2,+':!A1<!=()0#81%8#+E%")&;;)A';$DB1*%8+(+ABD..%!,./@DG+!5$(5&<0!D6.7717+;2::(F.H!>>;D#/F?9=H=/#3E)11'C:8$1G,(!!)1=#>5(@@8E"=17+=;(4C=;G+B-.)>.!A9C+C":G/&!F4>;=*C")3$"1>((/5A.H,3@8G&H7-AG2(3?<BC<2D5,"+)#%>04>$46C2=2*(E.%D3@)G*H-/&E1G6>@-37)-$(:87*/AE35"=!)D0AF2B)07(3;?1.)EA55B&**-=672,G:CF*B
@r4328
ACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGNCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCT
+
4?C6&H*7(+=1E=;:5&5A?1"1F>3?-AA'78;"%4>18,H3@>@F1F'!2H)0BH%F@!72%4<&F4&0#@59=1>F9(199:##-DA!&1D>06H1.GA"<6/1)>64(*<)-D'
@r4329
GCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGNC
+
#E.E%!#C#(B$B!GA<<<ADHD!6*%9*)5#=#@885)H;F("G,?D*0"&3!+%G:;(*D8"3A>(<,"5%6H4%BBH!)!,>D
@r4330
CCCGTTNGTNCNGTCNNNGCTAATCACCACATGGTTANTCTGCTCNAACGTCCCGGACGCCTGCGACCGGCTGTC
+
#*&'*')&)"&'*'&$!"+($'+"'%$!&%+)*'+))(%$'""+$(!!)(+$*$&)))*)&)"$&$$$&!)"(%!
@r4331
CGGGCGGAATGGGTGTGGTAAAACAACAACTTTGAATGGAATGNTTGGTATCATCAACCCAGAAAACAATGAATATTCTTT
+
.C)*==$D2(9<!A$)>(H7=*B5A#@0%0(!<?C-?B!+<"<((*@3>7:HH&/*%:D?2+:$.0CH@7:G(=<:&#A"0
@r4332
NCTGCANCGCCGACNCGTTATGGAACTGGCGAGCCATCGCCG
+
'%*$&!!'%+!&"%'(")"#("(!**"#%+#!"'+(!#++(%
@r4333
TGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGNCCCA
+
2H):2F)&;44$('>9?=:E>&)+E8!%4$3641.!62</F0AE5B0-9@&#)%1=8<4>C0/H>BA'1BD&*
@r4334
CGGAAACGGATGGCGCTGTTTTTCCGGGACGTNTCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAA
+
C1=&?<<!:2D$4G1?27%:!+E8.B&@%+3-!87E#44/G5BC?4<F@#4@B,+1*B7.>(@)B6><!BDH@E5)<E-0&0C2,=-C#&%0G,9E,058D74%<1?6:,.B!87=3A()0D+
@r4335
TGACGCAGANACAGCGGATCAAACTTAAATTTCTGCTCATT
+
"&+F>5H/G7,:G;,@G<%61FH2C6@-*.>1.D+)2$E-<
@r4336
AAGACGGAAATGCCTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGAC
+
+1.&:@9='D45;A4),)/7<(G,FC+'-!@+;?8?&7:C3!0(;@.*5!!
@r4337
ATGAAGGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGAAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCNCTCTGCACCTGCAGCCNCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGC
+
+B;<@BA1)>+>&9,3H&8+*?.43(3+3HC0F=#8;??C7$H"@.3*BH1G4-GE=0E"*BC&-G#1DB8A$E<=?H+"!2C,52*%C/@(/6218/.F3-.;5'-98'H#8B..==1-(?"*'>-GBDG(#A0=,AG%-((,1%35<',*H)"8>*#+6H7!;/!!@H(G!H7)B)<HFE40#7%C;7E#+.6$'#,6*DF6;4!7E;1.:3&F'.=@C@1)E-"8<
@r4338
CATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGNCGGCAGGCTTCAATGTCCCAGGCTGAGAAATCCCCGGACCCTTTTTGCTCAGGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAGAGCGGATGTTGCGGGTTGTTGTTCTGCGG
+
("D&./;'F;A!5)<=4#;+*%@%7+B!5>=CG8)3!E5$7DB!A.;+0-A'--#5@0F3?+*!",@4!FG!D-B2+>%$(=E2,C<G:&A5A/,&H&%!/.5>8/<37A'*#3+5%=(AC?).79A07*)$D8/7,98"//G:)?(/'/(D*(411*4%?$5F';DB**"<:*
@r4339
NTNGCACTTCTGNTTTTAAGCCCAGATNACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAAT
+
()!#%)(%+!'!#$'+))%%(&%('*)$%(""++#&!#%*$#%#)+)*$*"!'(!'&!"!%#**&!!)$&('(+%&*(&'"%"#*#&""#(*+$#"%%$&&+$"&*%&&+#(*&(#'
@r4340
TTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATATCGAAAACCCGCGAGGTCGCGGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGANACACCGAAGGTGGTGAAG
+
G*5!H<:B783B3;C5=70<'8>/E'H).E;%E21A%,1D:!>'E)6G9,5/;-A,/:>3,0G:0&64FC.;E(8"&B'</.!$B9@/0"6E#G!+*)/)"@)697;.+1;&<=1/?.H&%@H+=C#5?@GDHE+.1-<6E,6-%'$&'G.AG<>@FFG&/=/(;D&?4!E98@H!;8"0
@r4341
AATAGCGAAAACCCGCGAGGTNGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGNGCGTGAGTTTCCT
+
;,6@:)'DC!7H51:///C*4/&0BH&;/@:?2"93$&@!(@<@6C;92(:=A/GE-9DC+#$1/5A!F4?'B;!<!@2E<-1A;:%9G@)F!0682'8@6B1H"&
@r4342
NGNNNNTTTCGTCNNTNCANNNNNNCGNGNCCNNNANGTCNNNCNAACTNNTTNAGNNNANNNCNATGNTCNANCTNTNTGNNNANNCANGANNNNNNNG
+
#$"!#""#$"#""!##!!#"!$$#!#!!$!!""!##"$""#$!$"$$#"#!"$!#!!#!$!!##"$$"!!#"""!"!#"$#$#!$$$"#$##$"!"!##"
@r4343
GGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCG
+
H)%C%C'36!%'@A4@1F6"H<?:H+H1B7G/>;0DG)7AH&;3:72D/*;7'%>-'=(9C+>58((:F-BF3+#1$760&3@#.G%(4%8!530F%F
@r4344
ANAAATGANNAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGNCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGC
+
!")'*'''!)+(#(&&'!#+$+**))#!""!(%$##$)"*'!'%!#&$*#((%%'"+"++*$$#)***('+*)""+)%++)&*'+"'$+#(()!)**'$#+#)&(()'$$&!)'!&()'
@r4345
CCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTT
+
.9*->F$0+86D:A?:A5>0'/09#!C'<%));/:.C.3H7@->
@r4346
GGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGG
+
0?%GHC77D.4#3%-$@2:/:F5>1@GF-<"B./E((-,70A(0
@r4347
TGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCATGTGCTGCACCGCTGGCGGCGTGACACNATTCACCGTGCCACT
+
:8'20>!72@4G=7:$(%!:>.#B+:&'&,<+FG2)2$#D&<'+625@C14%BFE7?-47?++!>+6F%$++@3<C#/1.6#2D$&2
@r4348
TGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTA
+
'>C'H80,(+?0*A0405=#5F+E*E753'4'3C1<$9,#<6EE
@r4349
TTCCGTTGCAGATGTTNTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCC
+
005?56G%,A!2&2")<A8*&>D@81BB>+@E@%2""D79)&";8*-4%3C<#%3$8A0@70!/60'85"?
@r4350
GTCATGGGCGGTAGACCTCTAAATCGTGCACNGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTT
+
'B@1?-2@$F3E(:DCC2="9#24($6;-+:G?AC3F:.<9,3A)74?;H4A#,)#70<:'%;@==-@40!;&(!4:!$+5*.*1F)>/%4+&;>-70"H-.#(F,HHD56=F"C158/*7+;$)=<4;*>>3B+*?H4-CD)%B0(#)$16=(&6.@G15@D05:0*!D'B&;,#D&&/#H$?9<:8=/1&/-8*-"!G4,#5"9===@<::-&)B4-;2FF#
@r4351
NTGGCGTACNGGANCCNCGCATCACCTGTAATGCGTACCTGACCACAGAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGC
+
'#)%)'')%""$(#)&!+*"+$&)**%$*(+****'$('!$**)$#)!)'&!$##+'+**#((#")')#+$&*&&%'#*)+'$%*+"#
@r4352
CCNNAGGCTTCAGCGACCTTGTCCACCTCCACGCCGNNTGCAG
+
))!$)+))+%(+(%(+()'**%&$#$%!&++#")")'!#%#"#
@r4353
NGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCTACATC
+
(#48362#!?%,0C#F)-D<:7=A@)@%D>1F;5.1G7.=3F
@r4354
NTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTTAACCACTTGTG
+
$3*H-@348..,(%6F;<F-;(2$569*8-'H26'G?%'@D'E?(!&1$8415'(59F###6$!AA>*;+><+E=$?*#G4C75)(<45"2<>!5G:
@r4355
NATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAG
+
"*/:4'/.67+93<?*H-=/58'&,5@:HB5>FG)4&6%=94$D/;H4>*#
@r4356
ATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTT
+
2B*8&'>E4'!77*C</;@2$#=E),;A6>C6!%)G?>E"#1C!A<*G=(;@?8$,,E5FCE5;52GG"3*6:(!".89*:"$./@8.(2?6
@r4357
TACCACCACTTATTATCGCAGTCCGATTTGATTCANAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGANGA
+
B;57<%9B4'B'54;0$3'3/*H+.$071C5207EA1+$1,#?%+"/782+C8*%&82DC9;DF#C%<?$*H;AHG%9&$)-"'G*.$'#7"8$:/3!7-?7*'(>87G3=1B>
@r4358
CGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCC
+
B2A'28>7H;AH?<#AE49B#8A:!..6(BH22HA%-*46'*166?,BE(:!#D5)-8&#@+F?B(B'>3%4-<0>A.5CHC3>)%(G*&(C;83+9%;@4.*;G
@r4359
AGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCAC
+
.$G17(A,<D/<<'*H=,<9B/G96(&F;=6)/(2*G;?$E:&C(D#<GFB@71;2)3)#+DG48)!G68=)
@r4360
GCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGNGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGCGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAG
+
$0;+CC#&%CC/()/.EA9,HH,874&6:)":F@@AH=..';;#H//*=86'-2A>H!$)=#"+"3B1(E<-+"66F37>A(''4<CH<A09H++;2B&6DB8D49A6;B&8'>*++5A!GG2,)2'E*;!E*=B!;=D3#/++'1B&$;/8",,@'=)=#D,21.*1<&H996&:(A>6A(E<*$
@r4361
AAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAT
+
<4:8BF;#FD&F;<A!CD='4B9,8,*#:+D3?<5G2C0E$06D$:;&3>80(F(0H*B!7(FF&!-8=(=2,+#5#B&DG(,0
@r4362
TCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCG
+
*DD)#C?B9(99$%!;*14H8C$&@A)4,)$5)B!>-368A<B!G!2*@@418>&-"F,0>#C7G?#:*,3H9(E1$(%DF0E6378=>0;&/;8;5>%:<0
@r4363
GACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATNACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGT
+
3$5>''*(5'32A%/6"$?01;G:3;@:E6A(+4FE*3@$"FHD.(4G-;)0C"GF%1;&#7-<<C/(F1E0BED3?5,>/?C:3F+)<*60=!-FB%+8)/2.7+4)GH7$A'F"+F-5+*H3(=+,/1==
@r4364
CTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTAC
+
G,2B7E)*./7H&*>/*D@08#)E4'DE=:9F;CC4.??%<*%GBBC0
@r4365
AGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGA
+
;@('-7!/8;&7?<->=F5!3>,*C<;B="&*<AD/8BE6;BD4C.2F.C8%,80
@r4366
GGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCTGAAGTGAACGAATAC
+
/$CB;,*C6'$.7DD%7+H.7;(BAD@>C0*/2CA9C8-)9":C,9)8(%:2)&!1&)5
@r4367
TTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCG
+
-;!F99%9$@64-*D$2B2+E/;>0$G-"><(3F:*'4(G;/'4$<#@>CC%E=E+:6B$FAD<;79DE+DE60D+;!D3)/<BC3"95%=F-G)3BH@$-80<G)%')&)47;4;G?"&6+#*!C=
@r4368
ATATTCACCCCACAAAAAAGCCCACCGGTTCCGNCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTAATAAGTAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCT
+
7G>$.>61,:=9+C02$;"/7B;0'2A2G/@)"E/A$=!$E;:1@F=9>D%5*(>AH3%%/;)H>;-/4);F<(+B-)H*+3?FE<4EF,/2G-*#23!)6H2+7#*/=0FH90(+B:FC</?8C<3>/@6.E;1/'4D.9(+7*.>@DB6"3286/<30EG6.F<!&2C9?2F1#A/H$C
@r4369
ATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGANGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACTAGTTTGGAAAGCCAGTTGATCATCAGCAGG
+
7%%(@H?59<H9/&A+A6;69:'>>=H4)+0:6+#3@C:6G2/8<#9?4D3<>CH$3":"F!+(<<H!4*11$<H*+&0::6@"%A$C%/9=.**><.&/99G0F>;9#=.+3FE60(48E#AA?G'2<94#CE%.9(FG)BD8F194#+-6E$323633<;?*%H%+)@'":4B'C%52GB:.)
@r4370
TAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATNCATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGANGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCCATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAG
+
<DGD.)?AB&#:6G%)B2#7*%D<>5+6EH82H*D!&9E!9HB,96,'<4>(50<!@9>&&6@'1+4*'>.!595**A:;*A984+&..0?<FC;#"-D#,/F)#=3$G")0.F:A8)G+4:+.'C00?;"+'0(7-/75+>DDG72A6B7&@E3D>(D,6+2C1*?7%:$FD)F;)CB4!!1E8AG.?>%0%?49!%9)%>-/2%E(*
@r4371
ANGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTTCTTGAGGCTTATTCGGGCGNAGATCTGACCAAGCGACAGTTTAAAGTGCTGNTTGCCATTCTGAGTAAAACCTATGGGTGGA
+
##3D="/D1,G?-,HF;1E6(('"<*@!4*7)!>=18H$4G%'+'8?<:19<F2!.0$,@1CG6'*?:EA45)*A?@="H@.)@E-&1!'"$C<$17:F<3)%C:<A:2=H&D3!#?)B4;5$21!G8+
@r4372
TTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAANTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGNCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGAAATAATTCGTAAT
+
''+)&((%)"##$!+$"!')$"(#$)$!""(&)''""&!%(*"*'+))!++#+%"'&$!#('&!+)%$%$+'&$'*&+*++)%(%(%!$'(!"'!!"**#$"#&+()+!$)'&&&!!(%**(!%$(#+'%((!))"*+*+"+"&%"!*+"(*+')%*#+##!('''#*'(&$&!"*$*(()!"&&)%(+%&)&))*#)&+))($!""(**)%)'+'&(%&#')$+!!$%+"+&)&)+&)*+*##'!)&*'!"("'$&**$++"&+'&*"(+*&"
@r4373
CATATGGTTNGTGCAAACAAANGCAACGAGGCTCTACGAATCGAGAGNGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAANTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCANCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCTACAGGAG
+
.E%"99#C'6GF;.;?BH)*2:E)94E8.420A4+0F(#F)85?H)D,)9$154.G$2=F&)!;<<=B%2&)=)26G?BCC60FAG6!;C4'HC<"6?,3G),E20D/9HH.F&.;:?FCH=+69)?H,#!;@H=;+!/58?1.>4D74AA"E23G56'7!/1B#2*5=!(7@C67><DBF/1!3F19-?')H;'*>/!0<.A901=#0,E,BAB'D.-?A22,4E@?19A,6<@@,4&(6,#"/A/5)F7(A",?HG)?/04CEE3D#-/$@+3)0H6+'%9G6#%8D39E34@H$+*$0.#)9,80<A<+7('5C4,2@*&%?$<
@r4374
AATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGNCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGAGGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTG
+
0'64(6'!1E,C@8E",+G-1/A"$-*.)19;0/(%(?"#&@/,1DC;)*H?*8G5<F1,F,2+8';6A37"+2/&BDF@?<=!<:.F&4&-!7A#;%5-'$H+,%!8)29@#E%)"G-@0FH+8>59%,8@,B)"$4+%@4'@96'?7/0!;(!G3FA9C),DG."3G7;9:?;4%'59$9?D$>8/>&34A<2+1;30%5":F827*:/+)+E/F'4(E*-53,3'E9./.6@@@8>D%F2<%5$9!*!E.H6-EH!9+=*9#>5+59C'D8E@)-DCG@A,D95E8/C&0+0*,?41858:B?E?/>78
@r4375
ATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTGACCTCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCT
+
>.$@3:"(H9C30H-$0E5'<:1G1.1H+=>8E'/2C9@'E)D.'%@H*F;-B;"!(!E?B08,*=,8<&->%5:E1C*DE81.@%.&-C
@r4376
NGCCGACTCTATATCTATACCTTCNTCTACATAAACNCCTTCGTGATGNCNGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCC
+
)#*#)+"+!)!#'$*()#)($%%+!"%)'&*!)!$$*%(#!((&#+(+($#"(+!!#'!))(*&*$#$#&*!#++'$!$#(%$!)$*!$)&*#"#%")%"%%%!"**$#*%)!"($)!#'+!'%+&&$$+"+($")+!('++*
@r4377
TGCTTACGATAACGTAAGGANTTATTACTATGTAAACACCA
+
H%G/5'4B7B.174H'/H4+/0B%56%!$:69A;3.3B6G"
@r4378
GCTGTAATTCATANTTCCCAGAGTCGCCGGGGCCAAGTCAG
+
AF1#5#*91F9B"H-C!3/=(EB0<A;D4,G-='F0EB$F6
@r4379
TGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTTACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAAATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGG
+
1<"7GC($?H+$62!!)*";@6C%7:(6F:F#!5"+8:+76%/@%4/@<91#<H95F20;8C.7G+#*E7)$G-C,,51-&E"H<<5@9E>>9?A(<&.2C?2=&-B+D2C1)?#*9",6E1'GFC5?2@F?!+):-:"7D!6202**?G4<%3!"A-&698B;:.0(.:3=D9H/92+)1%!2/9.(=18&1/)&-"$7/CE<,1FGD0<!3'7,?=$$#@6"?$.1.#>*,B:A-C45F84'F"D77EAC0&%9>A5.;E##+H<&4=#7%@G++*&1F'3>B=5>%E?(2"
@r4380
CGGTCCGTTACCGGANAATNTTACCTGGTTATNGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGGACGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAANCTCGTTGCTGGAAGCCTGGAAGAAGTCTCG
+
+*!'+$&+)#%(+*%")!$!&')+'*$'('+(+")!'&#*&)+**+%'!%('#)&(#'!+*%#+(+"'!+)%%##&)%*'+!+"++(("$!(&!"*%%+)&*+&'')*%$&+)$!(+)'"#+$$!'*'&$&*)"&*"(%$&*"+"(&&&$)%$)!)#)%)($'!%&$#*&*$#'**%&&("#"%(!)##!"(*#)!#&()!&'%))(+"#*"!'&&+")#(%&$*'"+'##&(!(&"*(*%+*
@r4381
CCANGNAACNTNGNNTCACNTGTANTGNGTNNNNGACAACACAGCGTAAGGCGTGNGATGTGCTCAGCGATTTCTG
+
!('$%*%'"!#(&)"(&*(!))*%")##*&$%&!#'%#'+'&!)*#%$$("#(%#$$*''(!&""))$#%&+'"))
@r4382
TGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCGTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACCCATGACGGTGATCGCATCGGTGCTGTTAACANGTTCATCAGCCAGNCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGANACCTTCTGCGCAAACATCTGGCGNGTTNCGTCCATCCGGGACTGCAGTGTCTCNCG
+
0>A)0/=#!&@,#;38B;507A*B9-*8<8#G7517AFC7@.9G8<&?D$8F)<":3>EDF0D67.&%497<A1(7,);=="(4@<CE0A;;7>-?C'3154/9G>H)!D#?/!7$@4)-':+:!G84/5-CA1-6$49/?*7?&4>:-;@.0(4<A,96G/+)>4":/+7@9E9;0F1>%/;39<!!1/%H%)-#1C=.72*H.;85-!/+E>:9&7#D=E/'<8",-#-.'=?.47:39:=:DE-FF/!2;A>>;C$74;(#D4!CH%!)C/5C$A2!7!:--'6904!@E.<D-.381862!B--62?'&)#%!H8E//><86"8H-.6:%:14-',CE--%+:C&H3:;
@r4383
NGCNNTATGNNNANNTNCNNCGNTTNNGGTGGNNANNNTTGGNNTGANGNANNNTCNGNNGTCNNNNCNNTNTCGTTTATNNGGCGNNGGNNNGNNGCCG
+
!##"$"$#$""!#"""#"!!$#$#""""$#$"#"!!!!#$$##""##"$!!!##"#$!$##!$"$#$!#$!!!"#$$"!!##$$#!"$""!#"!""!""!
@r4384
ATNAGCNNANTANNACCNNCNTANNNANCTNNTGCANNANNNANGCANTTNNTANTATCNNNCATNTNNTNNGNNCCGTNGNNGTCNGGNN
+
$"$"#$$"""$"$!##$!#$###"!!#""!!"$!#"!!"!"!""$!$""$$#!!$$$#"!!$$"$#!!!#$$$!##"!$$##!!#"##!!!
@r4385
TAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGCCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTNACCTGGCAGGGGCGAGAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTNACCTGTACGGTATGGTCACC
+
,';7?BF+#6/#?490>GG0/2&*.G'+6&!-A&H(4F5B>'C*$C4.H?;?G#%A!%.DF26#7"+=8G7EG'?H6CHF'G0H5$1.$'1;,&':+HA@:/:6A7/9E1EC0?28#+E*(3=%E6H9H&6-1F=%C!>7,8*/D8G50(%.A"1,#4)6&=&,E%#@0@A.C/45=HF+D;;F2*")A(A1'+E?&<H89C6$=&<($((,0@0?'?-,B=*//((.#)CCA2,,H#%30F!"0C=3076EE>'D62'1+A(9:?4$@5FG@F?0.%*/H!)H5@(6014*E8D"0./81F,@:6':*#F49D/CD>6C*$.=//8E0.E"976G,*5B6=:A2="$/CA$
@r4386
ACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATGCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTG
+
&A>;>0#;?(%?$>D:2?%&#H*?D$GEA2*29!6'66>;.>CD:;4C$=8B4A.$6"F=3?/#<4+'D?"4*)!&*EC*<?=#7G+4B'=BH9GBH3.7%;,C@B(@EF'?BG*7=1.7
@r4387
GACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATNCGCAGTTCANCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAA
+
;%D$")B8*$>)7""'#>!='0$CF4?"=)A(8-54*..2E9#@25A<8%+89455,-;*A8GF8F;4"2'+!H=G6)(@B-:,=(C(%0D42.865:?0.&-5EG>;E3G0%8*"B%*C(#EAD0)3GD8:79=3G<#H35,'=-7$2.>*@.181=>G:@69E0*?"*E<!!?F<</3!02@>C5H.;8BB6/FC*=>;
@r4388
TTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAG
+
/4.1F59>B1D--0B(,"-$?C4=A9D(6A.0BFG<&35*,"02)F'062<+=?=
@r4389
GGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGG
+
$'/'1E?0>E@C9%!)&:))"#,:F?E*8AF@7>(,*1>FB5<9!'9#3E7A0)/8&(C*B70C
@r4390
GGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGC
+
608=#"H+)H(1*4D,06(;1#4A:2>(@<?1A1+"71(4)*?.'2.=#8$B$(.:A7+
@r4391
ACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATNCTGAAATTGAGAACGAAAAGCTGCGCCGGGAG
+
6&>'HB-?,4!-113?E.1+,$AD@7D)EDB19?=:B4/<BD%2#+!-9/4!#)A2H0C=/<2*5/#?3+8
@r4392
GCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCA
+
8*52=&4#)C0!CCH9..)'2'F)1@1/B),"9G?&+D132A36@4F?63"-0GA5$
@r4393
CATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACANTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTNAGCATCTCGC
+
:F1C:1+,F&9886CCC>F>?*.()1+&GF>"3$1D:*7$@#A9;7<<C!G4<4$@%#'*9(*=A-H'*4>F.H7C/H907:*#!<4,?'9;/6("@!.,0#5,2E)#1#0C2%.&7&-:'.3)'<534G1&%'35H.;+<7416!?4<*8!D,:(7GB=G>/BD"D:1%D,#6G'?"!21$G!.B=++<8?(/FC,@0)9C!9,1'
@r4394
TTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGG
+
-9"A4-$BB=@)/$7#7C"/!-<>!50&6H9,$'$=-"?,
@r4395
TGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAA
+
@.+(B4&=>//%1):(?2'0.5#2$9/=2B<;;"4E?2&+>%&5;;
@r4396
CAGCGTAAGGCGTGGGATGTGCTCAGCGAGTTCTGCTCGGCGATGCGCTGTA
+
$+$'%#&+$"%+#&$'##'#)"%)*'!#))!*%***($($*%'$#%$+*$%+
@r4397
NCCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCNGCGAGATTGAAGCGGCANGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAA
+
!!'(**"('+*&&%)*!!#&)#"*&)(!%&"%%#()*)!")"(!%+'!'()"#++#&"#'$%&#%)&+)(()$)'(""+%"*"&*&#+)$$*'%)!#$))$+%&'#*&&)(&$
@r4398
ATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAANTTAAACAAACCCTAAACAANGAGNTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGNCGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTT
+
+!&($&!%#+!'*+%%("!&$+#$+(&&+*&"&*''!!##*""***$"&+%!%"#&'"*!)$#"((")"!'%%*&(%#(+)!&&'*)$((""()%$!(!(&(*(!+#$"')"$%!)##*!*+)%*""&('"('&*+!!"&*&##"(*##'*'##$)(%'"%!##(")'!)%!(+!*""'(!'!%!#')))%"$&+%(")$'+!)+&"+"%(+!$$)'!&$$!#'+$&(!%)%++()+*!)(&&*"+!"(&*""%!$)*$&*+&((*)&('%%&'%("%!%"'"++!$&(&"')#!
@r4399
AACCCNCCAGATGTTTGCGCAGAAGGTGTCGGCATATNCCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATG
+
+&&)"!'$($&"($*#'**!&)")#)"#'!#(+*+*##'&'&%"**&(+'")+%((!*"+$*##%)$+$&)()&'"!+')&*"#'')&&$!)*!*!!)")'$%%("+#"+'!+%('"!"(($#$%($$)"#''%$&")*!+)%&)!#%*%"("!&%#!)"!'$')"(*"&'!'
@r4400
CCCGATGGTCTTCAACGAGATGCCACGATGNCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTT
+
=6:<<'9/9D-G&'A+/636,(C?B:G41AF9:+B6BA%,FB8FC-G@3D4=C.-&+&.12,"=*F?:-,"2HB,+BE<6=*A</#H<?0D6/BD+A
@r4401
TACTAACGGGTCTTGTTCGATNAACTGCCGCAGAAACTCTTCCAGGTCACCNGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAANAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAG
+
+&7"E-F*C*.D2/CHH1-F,ED>C"7$54BG947!B,$0$(70)1#$!.B8?C4*B5+.-,>E/*11B-<BH$<9(0:G,AC@'G+%A-=1*<-98=,#0A%F?+@!.F-98=!5173CB?A*.!"C>8F<>F+&GF+1C23
@r4402
TCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTA
+
2,A!$%F;:>04(-A<+'FG*F"4*3;<G2=BDA9A0455!3&!6-<$562F*+"9F#,A?)$C<:116FH!
@r4403
ATCNCGTTCAGCGGTGTCTGCCAGTCGGGGGGTGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGNATTTTGCAT
+
$3-&79(.@4'1&+B5G=8;#!!F=1@C#)C./(C6>62*;@0@?8:7E:>#-DEA+D>G,$::43#E7394.<('%E@9D-5,C042B,)1F8?%8-D>(?'BBBE51G&=0.$F@!02*?500@3(HC!B*%2:@>/A;4C#>2C4E#$;/":.=FF43H>0;HFHH<835(3,HE,D<3(G5
@r4404
GTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTA
+
G<D)7F!H:@C&#$@6756E5G410,0GB=.;1F9::8;G;"7((%#9))$.469BE7+882G7-7GG=%.;71<$1D7BF7<5
@r4405
CTGCCAATGTGCCAATCGCGGGGGGCTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCANAA
+
9C8F#!1@!-;2!#C3'=E!-(DHD9=*C#0:5(2%9@9+@7H7D$?@28/+'B(?&3/++G'0+@89E(6*F#4&3$C,A85D3,2C4HA(4<:2
@r4406
CGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTG
+
8"*6@1F2-351#:$+C'(;DE;G"$9@0-610=0@1''>61H>+=15:7."@+66%H869
@r4407
TTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTG
+
)H/!4>A@4#!)5";46BB=A("DE=+#)-8#$-0"5D6C-#074F-/,;12=582+
@r4408
CTCNGCATGNTTTCGNGAATCTTCAAGCGCAAGACGGGCCTTTTCACAATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCACATGTCGTCTTCTTTCTTATACGCAGCCTCTGCCNTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTT
+
&(%")&$'(#(%$%$!''!$+%+"*$%)%(&(*)$&!"(*&%$+("(&$#"#(*+%!*+$+))!"$(!)''"("%)'*'&'&&$**"&&#"+'(%#)&'#*&")!("*'$'&!""+('+%!+'%*%$+&%&)!&"'*$*%&!+)%!(#&#+(!&$&+$')#'##&!)))#$"%)'')!$&&%+!+%+%'!**&!#%'"!#"#*"'())+)
@r4409
AAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCT
+
2D#(2*!><4H1A6?(8?(02#B1FB,C=0#;?8G3!F?:A<;34*0:F@CG!;0AD>@3B*#@.D#9$-+7$@6>!&@DA:F;:)&4593#<(H?.B($:86=<!4G)9$-+%
@r4410
GGCACGNTTTTGNNCCGCTTAATTACTCCTGATAATTAATCCTTCACTTTGCCCACCTGCCTTTTAAAACACTCCAGTATA
+
")$%"*%*($%##!*(#&!'*%$++!!++(%"#!($''&+'"#("%'"((""'&$$*)*$)+!"($($+''(*("+)#&#)
@r4411
CAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCCGCCCCTGTCGGTGCAGCGGCGTTTTCCAGAACTGGAAAACCGACATG
+
4(EB65*'(!5"/*$8HD(9@66D,/,>*31C14C0D.4(,040!-'1$D?3C9>)0%@0%$A.EB8?HA*H5-%!637D)A@96*3'C')8(?(&);:*(5=$.A,!63/,@9E.?#%,G.;H>;9-2'*BH&"3@-:>"GE;H*0D=,E/9D/5))!G,E1/*0
@r4412
AGGATCATATCGTCGGGTCTTTTTTCCGGNTCAGTCATCGCCCAAGCTGGCGCTATCTGGG
+
&G,1@,-B%C-.H)!):29DF173#E549*03(36C%;(G/5)5-!)805;<4?0!;+0>3
@r4413
TNNTANANACAGCCCTCCTCATATAAAAAGTATTCGTTCA
+
%("'%"*'+'*#("%(%(&("*$*)*#+&"%$#+'*(**!
@r4414
TTCTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGNAATCTGAGCCTCACCGCTTTCCCCCGCNTTAACCAGTGCGC
+
*7E2!75D0HC>%7G7&A6):0%;(F7'-)=#A4+.5!<7G5-,$6-B?G?"D.-=35,.01>FB,H'>9&:A78-2)/-A!C<7-=H=(4?-5&;G,5!
@r4415
GCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTNGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCG
+
-"&+#0HC;+A<=0<2C"F=9H>:B<27C+;+,<AG#B%;F2FG&=B*-77,:,&&*5D)9*<4"#:$;<<4H"2>?'#1A2#E-#
@r4416
TCCGNACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGCAGAACTGGCGCTCCGTGTGGCAGAGCTNAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACAC
+
;6'D")+#%EF$B3?(B&-&AD'C!"-$F#.',+,!AF%#+A0@53%G>&/26*A6HB)C&H=H3*,;G2.@>:0,5B*D6F+"!@@.=>,+B15&%!@3/.G-DFC?/2-3#3:!,"4-F+<1B,$;E'3C&-H15E4<D3895@=<H!D.8(3D/%@9&;F:<0)#F%)1<+?3)7=#FC.$?4=F6#1G'6<60C=7,)'C"E/.:C85A.F
@r4417
NTATTGATGNNNCNACACGCCGCNGCGNACGTCGCGCAGAGAAACAGGCTCNATG
+
#$*&#)*(&$"#"!")()*'+')!#')"*$*&*('#)!+#+*'#)$&"")+'*($
@r4418
GATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCT
+
.D"HEH=1-0C.,CB?1'EFBAE+96C8+@%C5HEH**2E(56<2A51$833FG*<G8><?%1!BEC6F+6>,%?3H./8#!0
@r4419
GTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCA
+
<-29@H"%5EC3D!,;$$!1'D,HDA@"(#-5,EC$F*1$
@r4420
GGCCGGACCGGTTTTACAAATCAGTAAGCANGTCAGTGCGTACGCNATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGANATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATC
+
-A%)=30F,($7"::HF')"?>=&-@D%E@:<E5AH#$EA0H';<3+G8::5AH7@#F3H2D2$E.)C*89C)'6*F1#&3/#2*'(HB4*$6$&>$4!#,&8+80*,.;*C(A,,-A3)'182-C=##/F&D<9%>>F,%B7-:=9C5=-7.5'>(/B%0;2$28=)A3?&,.9D:A'$782:94F@&/EA$'5E)D-5B=4
@r4421
GCTCTTCGTCACGCATGTTCTGCATGATGATNCGACGGCGGAGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAG
+
+%640$)*&?37"10B:39//<8B>CG;922H!EF"46,.A5E78)1!?9+8&<%@&2(05E5-'>871A#5G4@5&E2)'&:*:
@r4422
CANAACGTGNTGGCGGGGCAGATTGCGTATGTTGCTCAGNTGCNGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCCGCGAACGAGGC
+
*"%)$%))&##(%*"(%+)**!$&%(*'$(%$"*%*!*&+%$#&&!+&'$*&"'"&%'%$($+)"($&##$""$++$)"#(!#((+#"'
@r4423
TTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACT
+
1!&#&";9'3;&EF5=.0;7:HF);*>3F9+E8/<6=>@:B8*4,;2!5>#/,E4C"6:;G:?.1*2"G,4/'#7"G!03C1-$:98,$F-/3<9H0+!&)G7
@r4424
ATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATNGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACCGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGG
+
$+'!!#!)+)$'&$('$#"'&)!*!#%+'!*"(&%"'&!$'&+'*($*&((*%"(+$%'))+*#""')*%&""&&'%*%+&)"*+!*!%&'++$#(%##!!'("('&*$+*'#))+%)#)(*'!"&"*"))""+#+!+!($!!!(#($#'#)*(*"%#'+&&$"'++!"$&&&"$(*""'+%"#%*%"'($*)#"("&#")'$"*$'%&*&#(#"%'#&%"!%(')+'$+&#!*%)(%%'!%%+&&#)&&
@r4425
TTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTNAGCCAGCCGGTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGT
+
:F;?:$219HG.-AF@&@7<;@HH81%:%A.-5D!7*(A"=%(,!D:6"/>)D3-4(!(-A'"'D--BH?/><-4'";&4/F@B!8((<5""H9E,3,>*,$/D&,;?5H>G1(!0;(24F6=H?B.-":.7B-<;@4:@HC&?47<&'00.%5/$.9>>D?+G4.7)E>/%'D
@r4426
CCGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATANCACTAAA
+
)"5790%)&=.5=);4/:7/'?E@8G&%3B,)4%"8+89#&/@.=8B@*#,HAAF'H5D5;;3=@57
@r4427
AACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGNCGA
+
8'DH(:C*7$=#C)<:?,;C?D)4;4!820'DA752;36G?C)/"9B9.4D'#-:G2!:"%.&!@@+!8+=3'%:,E%=#@D2C91G/<-BB;-FC=&?5&?'*,,%GH&*".C6,/?)6+<<C-?;#&&;")
@r4428
TCTTCATGTCTTACCCCCAATAAGGGGATTTGCNCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGNGGTTGTTAGCGCGACCTCCTGCCTCCCGNTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACNATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCA
+
6/./G802H9&E52CGFB+F*'8!@-C*B6E3B6@7-;9!:(EBB5D1!?87*6,?&>2-2GF654H(;,?G/?976>*&&,G%5G?F7G:%*)*$-3BC3"%;,GC1D)C3>'$3D)43%.+.#%0&C&C23F$/71/982A2%)"$4".$;3#A-A(G#@=G%,)B*FD,H&.1-AH>=#9?H.)@D)C1='A<#6DBF;?#1-,(%/7D%;2";4@82776>?@=?/G2</C#B9CE$-EE0
@r4429
ATCTGACCCAGCAAAAGGTACACAATACTTNTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAAATAGAAAAAGACAACTCTGGCTNGAAGCTATCAANAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTCATGCACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGAC
+
EC-D67.>F$$>B84"9(1#(<,?"E=+0*-(2%E*>'8/<-8="/H(8D9$6G5'48016?$"(+5F;&+'>4(*EA8G;%*>CD>="?@A.:419B$&:-4/(;4#=5=;C?+C=:2$2;1C=E*G:!?;1#-,6"212'G7.C<9C0;%(&H5.,&9BEC'B'$4<396;3%>$$')@=H!FE"1E%C;,0&838?E(;D1ED3G3$3-#2>2%?68,@792E5.:D:.%/::G,0'&=%07#E5@E)97GD-7:#'(."C,%8A@3-D=*,;;:,D?)4'10?D2931
@r4430
CCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACA
+
/52B6!3)-0:C0C2*4F3+?57!C9%-7,$6/5(D=3GF(C5>'35,=C*D;*381+H?&#?<EE&,GE$<>F?.$4'FE8
@r4431
NGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCNATCGCGGCCAGTACAAAAGCGGTGTTC
+
1'0;,FG"47!EFE>+A'&.DBG*'1B,!62;>'=#$-6&+83%H2-H#0AB,1>=/?BH%%#B:%1%+06(1$%8+1):7B!7D-<D>A,@313%F/FHB%-%8.)AA0(-,G-(E'
@r4432
CGACATACTTAATCAGCCAGCAGTCCCAAAGAATGGATCAAA
+
E!9A:>F0?9/,'4(&<8'3;3D*+.!63F6/1&',*E1<)0
@r4433
CCAGAGATAATTTANCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTNTTTGCAG
+
0:@$&#B5CC0!D!/+B<)4@D-(:,.!4B?&3B<F8H81?B&(:7D<&<##D&/30##98'6>#
@r4434
AAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCAGGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTG
+
=+?$#00(+>05C&D.BF!&/'*B:A@47'97C!H=*<28/E8<$B%DFC)A@35:<@?AA(GE3A@6<$%;E6A4E&:2)@;C%723$1D7*<2%0560
@r4435
CACTAATGTATGGGAATTGTTTTGAAGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGAT
+
7/99>7?C5@!'>@BF%6E7.1D+?:+35=95#*HAA'1;;6F5<F;2,4>D6&ED<?$9.60$+7G91'C.G3>%5
@r4436
CAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAG
+
6A0D3ADB0A$H1DG.9*?3#2A!+D1(0A-56561'<,)F=&1@"!5'&H.(
@r4437
TCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACANGATGCCGGTCATACCACCGGCCCCAATGGCT
+
C:@1/GB2;%%'=FD%:,4D%H*38=?2E.4F7"<!/"(+AA(/&2,A1$1<7?+#/!'-101D"#9946#F,H=9*82#;8)#!666G
@r4438
GAGNGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTNTACGGACACGAACTCATCAGGGTCATCCAGCAGCATCATCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCANCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCNTTCGCGC
+
11$5=E!='&452+6):"#18%B"149H&>8BE%'F-/EG,+;A*$&(>$@##D<'9:=.E3%9<.64BG)"@-*)&,5)?0=<E2>8EB8DF;E3#7*B-@@=11:G:72"&>1+.5<!6?:,*'07F(3H5D0+0,,#;4?(69:(B9!!B;3@6A=#C64/B8=,7-.'7G,E!-&0#;AC;A5(C6>;%=5C"A<G3E6!3EG<B,688';3/>#102
@r4439
AGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGANAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGNGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTNGCCATCGTCGTGTATTCCGGACAGTACGTGGAAA
+
A3F2>B7+.%A7$F+31H!%$5EDC*57()?&@&%-;.;%2+&897A+A,,;>7$FC.>E"(502#:>6D(2C.;&2AH3>FC$/.+2?>.:!3%58--G7-525:!$+:4>$=*/H&?2?0<E$--A%>++".;)B$+E!++?,-41'-/3=66,%2697<?C1&D*:>
@r4440
AAAAGGGCACCAAATTAAACCACACCTATGGTGTATGNATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAG
+
&:512.;4'!0823%5C<'3'6;A0D>G#HHF--!%F6EF&H4'')+3;)-<49070069"2;=?4<@&H-7;E37D(B@1E.0817/>#D)?#+%0@?1AB&(+*0(*"<,,&H1;
@r4441
GNTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGG
+
)(69'1?</1..F*7E<>'E@BA)7D2?=B,?%<CH536"
@r4442
AAGTGNANNNGNCTGNANNCAGGCGTCATTTTTCAGGTACGGAAAGTGATGCGAAAAAAANAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTAGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACANTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTNCGGCGGGATNATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACNCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGGCTGACGGCAGATC
+
)!($)"'*("#!&$$!**"#&+""#$%#)'+"+&#+$*!'#&)'$+%"%(&("$&$)##++)$('$&*)''!)!#%+(!%****&*!"&)+!"+("%!!+!#!$!&(&""**)'%"*'+!"!$+&$#$"+!")*'+#'#!+*+))$%!*#&$'+*)%&$$*!)")+'!)#')*#'&!!$)$"#!*!)"*("*)(&%*'$&*&+)$+*)!#""+!()!)$'(*%)*#*#%!')*"*'($($(())&#!($"#)$)+%+$&#"%#$*$$*(#%$+$*)&#%'#!!$''*$%()!+'$!$+&''"'*&%+))&#!&'))"**(*"*+##")(()!)(()$(&*)!%'$(")$%(+)'&")&(#$!!(#%(%&$!#%%+%%(%%&#)%(%!!&!+"&")"&#!''&''$$*(+%%++!''"(&%+$"!#"+$''+"##%!#*
@r4443
CGGCAGCCATAAGGTGGATGGCANCCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAA
+
?=?F+6:*B9,&&"/6AB!9D"6"B<,C10".,CA<28A(:6+!0C.*-).*68$=%/8#.CB<'$GC$A9';!38<?9&%<.
@r4444
CGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACG
+
EA3$H2/B>30)?A2E=,4.%*AG22F(A"@7C881*%:.)A*")AHH:%@C*"/G-"2G:@8D/%@;:
@r4445
ATTTACAACCTTTTTAAGTCCTTTTATTAGCACGGTGTTATCGTTTTCTAACACGATGTGAATATTAT
+
/DA+.*<'5F$1@D@6GH>G6'CC5;:E$/4@*>>A*,&,0'$@H0:4<)C,<DDH)#28'09@E@.'
@r4446
GCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAG
+
=6#0.+607D;F4@"-$EC0)D0#FCC24&%0-&H+E;./2)A0/E%:!08,@(F<0A*71'D:>/@F."'@
@r4447
ACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAA
+
;%>"<?904$:/*30?!/2,8147F002H0,*:1>5!HEA>@06%HC?,(*!".DD."5;!!';;+9&"DD3=/-F/@7D$+-C/!!2<85"8FD()C/%"?=&&@/14,*&9*1H*5,8AC!%0C-@HC7047!>F*AC+1*H8EG(
@r4448
CCACAGATAATATTCACATCGTGTTAGAAAACGATAACAC
+
-50)&3(4.&?#+3B4.?=8A;4::!3-"!4<!<1</>C@
@r4449
TATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGC
+
9:'B$-8650.CBE&:B,%1F'1F13-$4G8D-<4@%544(,B)23*'<C>%8(92B"H6B&2A1.5(*.3*4G->>!6%8G6)-%&
@r4450
GCTGTACTGAGTGAATAGCGTTTTGCTNATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATT
+
A#FC=,HA3>H7!>60;H$5F%3?E":3GGAAF.=%<<;/&50=8=3&5=852#('&HDGGBB-'))%2:5:B8!B#B:D@9"4#A1@D@799/!1)4'@"<1B6BDBF5$8"*-9A/<6$
@r4451
CATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTNAAACGACATACATTGCAAGGAGTTTATAA
+
C7HD+"&(<(93"3D<-/6E)/+"9B:6F-0E+:!#E),4D:DD?$B=;?-C2C(.$=)9!A,9E*C'?==9=#37E97B,(H.A%0:G=
@r4452
CACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTT
+
<&,5)9!@6B6%GG+5@@4"%+-D/6D%*,&;.9=--&F1*6+B&,%2'>
@r4453
GGCAGAGAAATCACGGGGCCGTGGCAGTCGCNTCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGA
+
+G5>@-=1@%?E666:"1F'-'EB:2.>7*.%D),+&161-,6,)3E;C,4&0B@$(5C0)25-(>5'3=*?@A8(0-
@r4454
CTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGNTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGT
+
5$761=,2H8H>8B@6<4;=!4-!#%29B&5<8=9;;+!'1"2-@E0$35'08>4;>A.,2):E4?)7CG88<4=#F7*#>@=>"5=<F"-<:1H1HHF%?B.)<'95FF+5D8755A93D-")@#EG3@A85>%>C2B7,1#C4,<3
@r4455
ATNNGNNNANCNNNNTNNCCNANAANNNANNCTAAGGNTNTNAAACNTANTANTATGNTTTANTTCNNTGNCGACCNNNGTNNANNTCTNNNNNCAGGGGN
+
!!""$$!"""#!"$#$$!$!!$!$#$#""#""!#"##"$#""$$$""###"!#!"!###$$!#$##$##"#!"$""""$$$#$!"!#!$"!$$#"#!$"##
@r4456
TAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAA
+
3,=0)4:'>9G!'$:3.0'(9!2A,>;95'(;!$$A!!69F;H*$6$/204"3C8'3;B',A2!8=6%9>+6;.#%FA=AE:H99'.394FE=/2B)G24<+D"C=F:/@(%3.1#6+$!B!5F813CG'8GG%E7,*?6B!G5*+&-A-B<%/&1(B;51D!0EB,$31/*+!##G@?A730D-$6>
@r4457
ACTCCTCCTGCGNTCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTC
+
C8E/"5/(113'4C(99@)9%A1DEB15D(:7-E0'15&/)>B9-G$"2F$E(+
@r4458
GCTGCGGGCAAAAGATNAGGCCGGAGAGATTTTAACAGAACACTATCTATCAGAA
+
!+%(*$(&&+*"$)#&)&"%)"*+&!)!('$%%&"'%!"*#"+$(%(!+!&$#$%
@r4459
ATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTANCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGCNGCATGGCAGANANCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAG
+
3*E88"!7C9:G+A'"0/%0"7F??%!4/;=>%A5#<E',"&FH'B&A/>E/2/%/.%4&>)(H-,E":/HC0GAA>&--(E,AG:4&'CB@6?HD"$:;D"CG(.%$6FH;H;)%8H2#@6:F4;7#,&"C18&2&/(E-6633;A3=">!651:H>97DD)(F@?-(-9,$&;,<*)'F1&<3,-:2;88&?#>94/:+C4-85G8:FH@-78>-'6:*$?97D)8=28H&1--%#D&6+31"D%<'(5800!&2(D%DE
@r4460
CACATCCTCATANCGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCCCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTG
+
8.,?.@1!/05F/$)H(5!(<&%87D%&601>6)>!!F<7##=2/0?%/#A.D>;;:8HH6&G3+$9A.3$-63#%)3'4B(!)0!;5G>"25728/-9(C<-%H,+>:%1C.&+,(4FA;/7:;8F<A9@0917E:3%!(&"H+E3-F;2'G1"&<A4A!.47A3#48D;/!!%)<!9?/=?1AA"<46+B4+8?*7+$51)098$/=*B4DH$!/0+D&:F2,GHB)@!%G),+)F:5"&%%"-<!;H=%<'2+B"+D.0.A620@",-"'
@r4461
TCTGTACTGTTGCCACCCGTTTACCTGTCATAAGGTCATGC
+
5F/*1HD7?=4G#>!0/!G@@9'+?&)'><B$.7(2G>$60
@r4462
GCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGNGATAAAACATCCCTCAAAT
+
=(+(03.A<,&:3FD)H/9G=2)-5'H&7F$:<&6B./#1+3&$)9?)?")C7D#22A.1A;3$%>B($!A.$"+?7;C:!D':9G.>H$:.?)"4@-$8>(D>
@r4463
GAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGNAA
+
/=:4#0+@97D82!9854"@(7*)2@>4G+C'=395<06'!.
@r4464
CGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAANTATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAA
+
GGE6)(*:=9$8&30'1)HE:8-C=3#AA5%#:)=H$93'4H9C)/&/F2!+?HF'+FE<&'=?,6)%?>=0"G7<@6$=F<.1D.3E28('>>/>'1<+3FE37$90:E&+*-&?.-?&;$*?,(H08:F'-5C)0@./%$=E7$;&>>&?13-@-,9>#+5!'8)A>,HG+93$>$2?!8B0GH19@HB80C4;&#>95:/):2&(8,06+9.F97CHB@!>97.%C54E%81H+07?7F>CCF($C,+,4B1F%CD87!F#)C:)(DH6=4",,""B4-3<7E.'-8;(>".=F!11H6#!E')%'@E9(#.*A*G?9:/,?'?A6@"()$8!$+(=$G<:*;'F@*'6"66%G
@r4465
GATTTTCTCTGTGCCATGACGGAGGANGATGCCCGGCCGGAGGTG
+
A&$C0&"-F2"(016G5;F/F6?@,=1+G-/)#A.(;.456CE9(
@r4466
CAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGNC
+
B%</A9)7BH/;.@.*C+670/<=3&$;B@(E2-'0E).62$D=ED;%E)4(&'1@090
@r4467
AATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGA
+
B73(0+E%/F1#;D5A"=$C."$5.D#:%2*5D0A"C((B$?,,4>*6$2
@r4468
CTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACC
+
!H%96?*:8(F6<#2?$:72?$,5,9?*D"</4A,5%..6HHH:><2E@E/-#2A&C((B*<;/E3,F8.F!5!?=9G.<,
@r4469
CGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATC
+
2-H,0>1>EH,H#-:?#(A+DEG-::5D!/9>:6A7<A.H,-#%821F.=#;6
@r4470
GATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTG
+
;4=>9-;B17*5#>0@4<(D5(%'5*@3/">9)87E@+D91/+..259%08,<
@r4471
AGTTCCGTTCTGANACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAACACATCATCTTCAGGCTCTTCGTCAG
+
"'!&(#!%+$$(#'*!$$&"*$"*!'&(!'"!""$+""&%#$)%'"!"""(+#"#*$!))*%+"+'$!)+%%"%*#!&%)&*%$"*""%+)'*$)!&)%!#'"$'""!%+$))('#+#%+%""((!)#*+)**+'$%&('$#)#*'$+$()&'!$")&%"**
@r4472
AAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATC
+
#;?#"E8##22)8C(2#.4.=51)-9%2'E$5@7,3E3,<E@(#03&B"76?;F";38&
@r4473
TTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCTCTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGTCTTTTTCCAGCAGCTCGTTGCCGAGATGGGATTCGGTTATCTTGACTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCC
+
1=45/'0:7,@;E::&;D+!H-*2+";GA"6E)::',$$6@5<+<;1@$?%==;*9&2=#+&DAC9)1EE7(:)1560A8=G-/G9%8;7F-AE9AF79$4>96=.,903+&DC@+>!C%>2BA0!/4,75*@8529&=)876-':,%=/<"?5&'<%*?A0@?1F4E6,,,6A5CF-D7!;-B85&:4%494"%
@r4474
TCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACTCAAGAGCAGCTTGAGNACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAATAATG
+
5"58&.88F5E7'-$"<#!(8*068/*FA23.4'?BB*&DBF6/+5@3D3<5-.!E&*='#H2-?.!+#;::4<!>E!5?>&;&E$?55$$HEF/3&D)/FB%E+?(A+&
@r4475
NCNNNGCTTNTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAN
+
%)"!#%%**+$%++!(()"&$))))!"!%&)&+''&'!'(**(!('#"!
@r4476
ATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAA
+
=.+@B?/5)%B10>A71%$+2$#<C=@4E,.E9.EC(F4>0%DB.0*F;+0'%<0'/='1;:<%#212+F2>#$;A7-H>/E!E!>@=$=;@:%C46(57E@").?*9H
@r4477
NTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCA
+
,+=6:D'>>#0:)/"-5=%G10>,F(67182F@,5%%#BF/:;E:
@r4478
CATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCNCCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTNACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAA
+
:%@3>0@7?03:0#39?G5*$5D;3@HG4H;HH'<C581=<"<EGE-4%$B=G+C491,BF31C9=%%A'29&84&:)6;5@,;'2)=@8A(CDA<=5!)/6<?#?#6#F/#&>B(&A8$:A$*;6$%8,DC#>.+96%!:E5>3HDECD;(F494B!?;2:G!>E#%3!(>%!/
@r4479
TAANATTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCNGCGAACGATGGTCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTC
+
+:<'D#9(,$"#,=!?1-,H,63<7;8>/=#<&FGA2>3>>&$-E&/,<9G;?0/2?"$1D(7#8@*6:.2(?E)4$284(+C=>9/!8DD:";DF&7?2+>*;",FB
@r4480
GTGAATTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCC
+
8@($.:?B1;?F11?+4<:E05&-1<!02$63F7?;4(%@%<&+8A/0
@r4481
GGANGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTNCATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTNGTTNTGTATTTGGCGAGCAATGGCGATGACGC
+
&*':'<@>#2?3>-''D6:"E$EHH<C-8AB3/;@*8E+D.&*'8)A%H',%0(A6!;E.1)6C1'>H&!D"#'H0:HH')C1;+':*B,&&:3<5>A68H<&+1GG,57H(:;(':$",E;%A0$*19@0;.#*'CBB!(:
@r4482
TTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACCCGTCCTCCTTTACCTGCGGTAGTGGTAACACCC
+
+//=3<.DF*)38B517?>73,'!)-G>@D!>/.E@04<0?E/=E6:/H"?E3+43;AE6055!=G,)'A&F=4.CB
@r4483
CAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGC
+
@&&7+#D&)?75>F.:2-F<B(6417FC2*60FB)HB@)8%A8!(+GDG)*A;+!:7.5D1>3=#>D89<."(8$(8+CH6G=F137899D>(G,E+G:+
@r4484
TAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGT
+
<?=-<3B-A%:E#=7EFG&2G#B1;&8A4023**5D=C;?%<>5"1:?2?6:2+B"DF18F87>9>7G%B+><9"DA3?D95-D?%++C##81=(5,15F#.<E1*:,H9;DE:E)D0F4A709$5;*)1>
@r4485
GCANCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCNGTGACTCTGCTCATACATCAATCTC
+
.?@90AG6&;D<-<"#+>7F15.G57852F'?;D*F@#DC?&&1@3&6+A'H&?848@3CB.H.)%*3"08.%,;5.@@(8FE<8F0#D7.;!'?>3=%@,7:%F'H8/9A==<$E3@@=/9(HED:B1/!?,*>;@-'H-1=:$&1F84=F9"@)G:&?F,8(AB!?/<EH1(D"=7*'4H8(2-><72>=GA?-7!5
@r4486
TAACATCACGCAGTCCGGCGGCANGGAGTGGAGCGTGACAAGTCCACGTATGNCTCCCGACCCGGACGATATCGAAGCCTACGCT
+
*8G"@,A+A1;G18%3G,C9:3G?.D4-,C#2AE#+G",(;<1.(-E)4;,8#,9'/46*6%6&D*,8BF#+)5+E#E/&%>4'/
@r4487
CNGNCTTCGATNGCNGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGNCGCAGCGCTCGGGAATGATCCAGATTTTGCNACCACCATGACTAACGCGCTTGCG
+
*#'%''%%*$("#'&+&*(($''&)'#'#&)!$&&*(&!)"$%)''+'%+"&'(+#("&#($!+%'%!+%!"!*##%($$*!++((+"!*$%&%(!("%'!*(++$+$#'*&*!$*++!%
@r4488
NGCTACATGATACCCACTATCGCCATCGGCATTGCCNCTG
+
!@4&*:)A466+C&?<$$01*4-(/-17+/@G4)"1?07#
@r4489
CCGNTNNCCGCAGCANNNNGACCNGTNTCGTGTTCGGGTAGCACTGTTTNACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGNAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCG
+
#'&&$%$%!!%!)&('&$%(!(&$&)#$&+)'!$"(#%%'&!+'*+'!((*)##$+'&%#*"++%%'!!!+"%#'&$!%#**)*!*($'&&#$!*(%#"!(###*"#!(+$%*!)#%%$#"&*$(#"('*%)*!+&
@r4490
AAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGGGGATGAC
+
2.!,G@'.88/BHD$:$0"9A#614=8(D;8&F;%"(!406+)4;"+@&.@(32+6%-;
@r4491
TGATAAATGCNAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGT
+
%83:'5.=00*G99#H4C47.<)H42)H"1>E=9-$(806(#/B1(F%6D6D0202+'!&@75=H:=H!-)*E80F.#<2+B8$%/?D;'9?%)H>AAF$-79+G>.0E>-GF+G*FC3==!%<;,9.2HF1.?:':@.(A7H21=2DDE;.+!-81(>F
@r4492
ACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTNACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGAC
+
)7/'->(/1>1>38<1;)2#2;(6=-/-A8->',6%G@;."!&1HA?,(=3A"CA3@;?E'GD04?/(:""0;"C&9(9:GEE>C"C/A!!7F*#.29#?A84<):0&58,%6&E!B,$'E6)%#:$7G)8.5@>/%0+%A.;GH=/FB6H7."9,=G5;@#7&'G-H0B2/7D:-%!=9&0@!@H(''$D*0<"G11H+//<BH7%>F4-<$3AG!8$E/03<5D;&&.>E-:5BE7"-A
@r4493
GGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCA
+
47$'/694F:=9A<63679!6;D#&%E!:36>:G-4(+C>(*%G5<;/(B4B$CB?<2
@r4494
TGNNNCCATCACGGNGNTGGTGAACACGGTGGGNTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGG
+
*'(##!#)#*(#)'%*"*+&&&"%#&$$!$#%"*#$!"&%$(*%$&)(")*%)'"%))**!(&&$(($!($%*($((*$&(*"*+"(#&!*&$$&!)&*&(++!'%%#')$$$%
@r4495
TTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGNTGTCTTCCGCGTTACCCGC
+
&;#.>%E7<4""5BB%'='>($(45%2->C4!?-5'8B-G&#!?5<31;>@1:()C808>DD$
@r4496
TCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGA
+
;C7@%,#E/;G-@D3F8+4,2=4074&#"C?7;A(-&E(!'A=>@=
@r4497
TTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCANTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCNTTGTGCTGAATTA
+
E18B#1,2B?@;C;%3E56&ED0%@8&=@>->(:8D1$*&/C1==+'5*6.A+GB'%>B.%7/3:/H.%6,(C<AE5!'%91"3-:GE8$9-67931A5+!<1.
@r4498
GCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTA
+
62>70=%2882:*?0&D,3,ADG/=F'G+;3+&=.G$=*G7;?(.&;)G=HF@5.5."=@G10=+G>
@r4499
CGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAG
+
>89CD8:9BH,A38G9,/G4**%F:4&217>(;@$'FG=?>:;EH+?768%0C8DH69,;(758.:6/*&5-5"2F!,443!<*+H3/!B84H>:AC)#B)E6>&?F4("<-4.E>B60&H/(E+)<#7#>'56>1%B@
@r4500
CTCTCATNAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGNGGTTCATTACTGAAGACTCGTCCGAGAATAACGAGTGGATCCATTNCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTA
+
4"3&'78"</.C8'(%*E8*0>EHD.7<3:D,<C>'D9?"?242/81)8+A%3F%GH,D+"?#!;-E%BA8&D+*8'D'G)>.'+A1E"1$(+F&)07;::H(1!8.E<!55FB@1D&7041./82>0/$/;*/GC=.01.-11GEF&<5F$F">?-0:4CE1+#7"%<A8''AH;E+-9#5$&EH:++/G0@+'::9)0B(E!:/95!3;,))+-DC&83@59.F%,8>'!<%E55"9>(%#(%=663G((5A7;9/A+?#7+&@('1+44/<9F4#F:A#7(80"+>@E1"+/@?C)H?*B56&H>!BG#F,8,(;$&$;E"&%<)2BFH,(#1)/8*/4*"<>D8?
@r4501
TTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACC
+
<94.:@(4AB%8)!'":,8&?D1$%#(+#A+..;42E#?A;/!'0)C1C3.@B<4-3>8?!:/"1A?05A,'>33*/B9!9)3@C8/-E?H>9.:G)%.'#9;A$41>!2!DCE;26C6(?$)&)89!@91)5,5<:F+AG,-*:60*3H$8#A=EHH=3<B'#9'7.2$!H,;!B+!)@=>1F7)'H#>#10FE+2<B)>#09#?-9/CA)0'$2'57)F#ED+%#C,++E@:(B@&%19(#."B+'H9>=;2/,-G0C:;&B2@B'8-"$AA3((#*AD8*+2193,"!/28@<
@r4502
GATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGG
+
%..!@8$""?,4>9(B>.$GBC9">-925-B?"G:?=!?2%@7&=%;%C/F<#D6".?<H!:G7EBGBH"48E3>:)'2+9*6)G<%,&>'2+@>@GA&CB-02!916F/93D(B:!C;=/7<=HC25B:>#:F;"<-6G7&*/3FF/0?E/1"+B/3?-()0/C8'831G89%C#7(4(<D28*6E?(*2&?E/D
@r4503
GGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGTAGCTTTCCCGAAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTT
+
2=@H4D5:>>%(3@:478(D2396(1F)>:.5//>/$FD!A5>B32CEF2"*4*?3:B,202-&?A0#/G&'?*!#,@3$DF%E+648+<#==:G2)#0D)F*3"5!94*+6<1HF2=F5/=,=+;6A3G"E0/;?<?7#4F9$B,#/&12<+C"(+-%?1A4.?.;B.G$!;,C$5;';4()>HE='.>+FD>3.:)&!(-D"9=D3=;%82D.G&-=94/8%?("3<@",2(D?(9"931161*)=23"E(D.5:6"
@r4504
TCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGAATGACAGACTGCTTTGATGTGCAACCGACGAC
+
/94(34;6&7)B9(/0-D5#@@4$55@>+5=%6#CDH*C<:%#!0!D<A;"#2+H1&-*"A4GD%17,7'4>&HAE'#*;3$;.;-?;4)8$%2=:D4391-&(GC<E2/!%H-)A37.#H7!4>,1
@r4505
GCAATGGCCTGCGTATCTTCANCAAGCTCTGTCGCCGTCTCCCA
+
B8<,/'H-$F,7.3-@2<E51$F-*H%A>'A>B<.)"$D:1AB8
@r4506
TGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTNCGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGG
+
4)C3!;F(#G."%/3=:2D"1?5@:B<0<6-$<712,-$8+1+<4<>"C?*=AAE@"&<8"?;7>FF>'':/A&A/$$G@/=HH$!(==1672==ADA;.(@('%5''4=E&64.H)-0,#FE:1.B1D=F'$?560.4/A2G6D"@C1'5D2/=-.D6+:.@D3'-,?;G7HD400"4G?.&0<<7<:)D<B/*8<&/=B!82H(H%G<BG"'4',,:=9+'0B,-.23)<(+7<+*B@.B2)2=3)B0)%%$E,0,-72$%>)!:D!A1+.08HA<%5'A2!F&'>=D%,;B4"*7G/:DEH.?C!AGD3;$B-!"'&09>#C=D,@9DC"&;%(7.!*&48->(
@r4507
GCNAGNGCACNNGCGCTGGTGCCATCCCACGCAACCAGCTNACGGCTGGAGGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACNCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAG
+
*$&"$%&")*%#%)$$+$$!&"*'#+$(+"%"")$"""$#*)!+"&++(*(+"("*()(#(&*#!$'+'&)$$++)!('(&#''++*!'*!)%()!''!&!+#$!'"#!"'!!%"()#*%&(#'#**#%#'+"&)*%!""+%"++%$#%)#!!&#$"
@r4508
CCCCCCTGCAANAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCAC
+
G;$:*E)>9#5E6F60$34726B+<,8",!$.F@90C"B#*&'C&BB.805!*G#<246D'E):G&46=D>H/A4E10HH4">"D0DC82?
@r4509
NTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATNCCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCG
+
"+*('!&+$!%)$'"#)+*'%#!%''$"$#(*%*$$%")#"$+"!$$##&#(!)%&!(&%)""#+&))$)$((#"&*$+&##$&%#"+&&)$+&)!%!$!&#)%++*'+'''!$#('%!%#&*+')+""''+$!"*&+
@r4510
GGNAATANAGTACNACGCAGNCCCNTNAAAGATTNTGCAATGCGCTTTGG
+
'*!"%&%&!#%*'$*&%'&#!!*("*#+*(+%+&*%""%"(#*%#!$*)&
@r4511
ATCCCTCAAATTGGGGGATTGNTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAANAGAAAAGATTATTCGTCAGAGAATTCNGGCGACTCCTNTGACCAGCCAGAAAACGACCTTTCTGTGGT
+
6@778:427(7%E5!D!27?!81;$;$)A!#FA-><429,0<>?*..!:H>=*+>300CAE('5"@B4D!HGH7H2&A>><C.&E%?&(B3.@"6C%+%79+=C4'F,?<".F"#&.@D,57/HA8G2,/=(*6D&2@
@r4512
TGATCTCCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAG
+
=5*1D$">@95@075@*HH(4C075+5,'+;3"%18-0A93)5"<3./DDC)
@r4513
CTGNCNAGTCGTTGACTGATCACCATNACTGCTAATCATTCAA
+
()'&*!%)(!&('#&$&+%'$+'"+"%#+'&'+$)'$%$*+*&
@r4514
TCCTCACATTTCTTAGGTAATGACATNAGTAAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTNATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAANTCCGGGAC
+
2%;:>D08(?8>:?+H,,D9#711-G0!'">C4@B2E6##=<E=8/;62,A+55?99*"");:DEG*=;!/:$A'.>G+/HE;<0*/+;?'>+8&E432AC'G7BD9#+7%$F2!>-37ADG,;BEC$'/ACC%2%6DE8*=8D;:#H%8DAA&
@r4515
TCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTGCTGAAGTGTCAAGTAC
+
.">=#E'3E.&*H6,?C(>)#:A)4--?.B:1B?$.;575.'8?--A4G$51,1<2#8+7&7>A,81%+(&$,/82/")!G"7(=*G9@(FBF)"-,00#-3!<7."E3!'&E</#F44:4$>1,D8<,5)?78.365*/*?,B0>,#G-6-A6)->'?1C/B2.+B22FAB9%F4&68@*@B:2F;;";)F00/F)1A-C42=1@(**<D-+3%.*76;"6-(4*
@r4516
NTTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTCTGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTAC
+
*B,0A38.%F+09,%$'@3<5=##H-08845"F92>8*.2E#F.<C.0%G.7A<</1GCG6&>B0#,%5#.@D5E5E5)9(4?42
@r4517
NNGGGNNCCTNAANNCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCC
+
#($$#""!%)!#(""'++#)""#))!"!+")$'(#'$%$%*&%'($#)%$*%##+"+'")%*)*)
@r4518
TGNNNNANCNCCATGTCNGTGNNTGCCGCGTTCGCCNGCTTCAGTTCTCTGGCATTTTTGGCGCGCTGGG
+
$%'##&)!$#"'"&*$(#%'#""%!+(&&*&&(**('*+'(*&'"##"&)$*#!&#&%&")!+$**!&+!
@r4519
GAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAG
+
H,5)5'%H;;A*/)27<$*E,5FGE8C&-F81E,%,3#;919"+0A5/G4+1A0%5B35@:192&=C2+&#7E!5CF,(1$082("+,"#+:9-'GD106G:2F?B#H88G;3@C/=!)=5!@A<CB:ED@E#H4'$70H
@r4520
AAATACCTTCCAACGAAACGCACCAGAAANAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTAC
+
8E:%$/;@)6&4-4@@715#.6*AGE%@8+H%"6>;-"A6'"#3')A>=(0EA731%15"72GG#D";E5!3?(.A1#
@r4521
CCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATA
+
9G,*B($,*A6(36)H.5=*>5GH:/A"?!89+F@;+B9%+&3?&-41H/A&E$(+4?*7&/#'?G"%."=
@r4522
TGCAGCGTGTGGCTGGGAAAAACCGTTNCCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATTCGGCGTGAACGTC
+
7.E:B24A0&E=6;9G9,@(47?F/,&.3FD""#A%,)7-"B51>0GB89&2@A"$C.:@(!(?44+0>96/,>)$/2$"!+1A:3?H8G<)683#&"E?B9./FH57':!%C8
@r4523
CTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCCATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATTCAGTGGTC
+
7#>46H<!C(:6H4#F*4H$3:4$!"7<:<;91=.!9D"+=>70'5??!@&&CA=B<<2;2&"@G&:#H5@3?;."H!0H!2-C/-*(F&C!15BA1#E9595D-!;!?B&(G",,/H.F7+@6&9"&A:0)9<.6;1*!0?+"A&1')8D#=HGH"<@9:=DDF<@?HGB6.C!F
@r4524
AATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGA
+
8*;)/F>4E!F(A8B(ED50?A:H)>>A</66/&&0?>F//-**31/"726#GA>+)E+H8G?EE@.G-%);+E2@;$&;73G!32"@1&=C95%:B(=F&BF)G7%&=C"A/(+-
@r4525
CCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCG
+
:;7=@&-F'-3/,F#!.$1!:4+#EEE!C,<>&;!!:@HC3%E;7!F)76$B4&548>%8CD3HFD<5#<%EG"D=@=$@=<5.417:)
@r4526
TTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTG
+
B?2(A+>E<<!!@!'@=2.@2=D&4)E@2*3(/=?%2(A.4A1:4852A;D)<9069?>==72C!!/692224:HH4(09.5:8H6F8
@r4527
AGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACANGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATAC
+
8,?)1":3%C#>:7,C".E5,H5E*)44C40%*HDC,6>"-1",9G);H3?E!81@980.".+EA+.-D<-<3926<D(1B8-$C';A%25=":9<@)=EE3:'BE>!=5=C
@r4528
GGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAANAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTG
+
9<G#);+8><7<"36H-$@,$31%AFF=E32H@"3(+887,,0=:=E)>2/!/CD755"1'6'&:HE18GDC.1*8#1%('!5#.(7;$9-FD/(:>5.#1DH940'@3/')@H*+>:1415H%C$!+A<67#/<=:C("?<30-6=!F0A3?
@r4529
ACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGANAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGA
+
B-A%?84.+7"C7#.B9'(34$(@538'+F49>03:E1-)'6*F=D>EDB<+#5;F*%C!$H>*2=15#F<>?GB5>8HE8;H.?;?C%B,86'A>*%84@?B)5-$3:-AA4B!4G4,#6*!(*+;>-9*D?
@r4530
NTCGCCGTCGCCGCAGTAAATTGAGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCAGCTGTGCCGCTGACAACGGCACCTGATA
+
#$%%#)+$$+$$*$'#)#%'&""(&#$*!*&&%'("#('*&%!$(%)"!)*"!(%(#(++"!+%("*%!!+$'+#!'%#&%##%'(*"+!%$%)%)''"+"#
@r4531
TGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCANCAGNGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTTCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAG
+
FD$4#@&A>;+3-E6G#HH&E)8-91C'D5'"--;2!8B.7)+.9?5/$%CA:#D/9;6((2E?;3(C98="?.E66E"B'1D%)!-!(3-H!<:F8A0@814*A((:00E-!DG@:;3%4:>B7HA5&D8&>,,+3!"'@??521H1;DH0'>>86DG3#
@r4532
NTGGTTAACTTTGACCGCGAGCAGATGNGTCGGATCGCCAACAACATGCCGGAANAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGC
+
(&-%.C9#36;-(8"B,A8?6:&B0C7A+&-C"5+E#).*@)-G)-E.*(82:0%!%<A84"5%%:"@/<#.#)*<0;.F<;0-;$AGB
@r4533
NTTCNCGNNTNCNGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGTCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCNCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTA
+
'%&*("$%!*"&#$+""+!#!#'#+#(#(!!+&*'+"%%)+"#""+#!++!$*")&"##*'#*"'&*&$!&*$*+&#(&+$(&*'!)#'"#$"+&*"$*&(!!%)+%#!)&%!$*$$'&!&)")(**($+)'!&)(&+!&!('$+*%*)#)(%!++%("$#(+)*"!+*'&+$+*+!*)$##$(%%!+*!)
@r4534
TTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCT
+
H:C%>AE<(-)*<2#/3@&A@A/>0+#*"G=1;8E%%A=@&7A99%"G-&/+656G
@r4535
GAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTNACAACATTTTCTGCGCCGCCACAAAT
+
CB"7+5/,%<+/@);&#:H)2)F5%!4>?B.;2E;6$29H%.#7#$D098:C9->6.E)(:&<55+BD!#8A:#F(!8,13;C"*F"F?5,B,2
@r4536
CAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTT
+
0&...'(-29E=FB*.91!&D,HFEE%9+>:;6.CG4?-*'0,
@r4537
NTACACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGC
+
&#"9+*#A4,90<!!"C*H66(C>>E'?(+C>*4/EBHE+E%GA+:E"
@r4538
CGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCCGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGNTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTT
+
):8)"&<5$*:E5+:5'+"<5?,@1C@A-.'=E5#!EB#G95"H'4-.H17;4+C!'*<DB=/<"(>(%?!=%&2G&+$?,#@&7C#A2;#?:13,1$B?(3=A+EB"<//5,:94"
@r4539
NNTGATAAGCGAACCANTCGAGTCANTACCGAGGTAGCCGATAAACACGCTCCTTATATAAGCGNGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGA
+
'&&)%+*%+&&#*"+"$))$)(%"$$""'("+(&)*"+!&'(#)%%$'(!%#))#&')#*'"#!)$"!!+&&+#**+$#&+)('()&!(+''#*#)"&()'*(+%!!)'!%!%(#%!)#$+#)(##!+&%%'!!&""#"#
@r4540
ATGCAGGCAGTTTCTGCCGTGCTTAAGGGNAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATNGGCCGCANTGAGGAGAATAACATCACGCAGT
+
*3(5->BC!(<<+212"6,)#$B4$?%&-;-,FGFC)/6$G?4=)('%B4194&>&F$$+6*63G,(<A9!7?A4.=?.);1:-B9:,42<;16"+$C?C,4?H9%8C4
@r4541
TCCATCTAAAAGTTAGTAGTATTGAACTTANCGGGGCATCGTATTGTAGTTTTCCATATT
+
A65%/G6)!&".1<BB"F;/1$8?%/B<9>,&F6+->BF@B7-#<%41.;;$C$F$D95<
@r4542
CGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGA
+
>AH1=>729-"592H,!68+H)*09G!"D1>&18)>CE*%4-B#%DE,ED)#0,&&B'(.D!HF6&=#4:*BA:,28=?7<DB8839>;+EHFA(3;H8<$F$E828!0822-8C*D#,/=/@B47)&,F(<G:,-G)?4G6;4("*
@r4543
NCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAA
+
"0AD1%09E<?3<&"7"'/+.C0:4>5?"B$?8?>-G(@D."2DFF:>!+03&CAA#G<>BB8&.6,0C@$$7H4*&"*H:&4-0&F*8.@>4>)5(@!660-27GAGH9'BE%E<:#?61A1H3=!4G*)$/.-&,,AF>A4/D54+&#2:E9.0$;=;39C4.-3%*6E7<@32>/
@r4544
GCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAACTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGGGTGTCGAGCATCTTCATCTGCTCCATCACG
+
5DE$6@)DA*C/:82"2<,65+4-83'G.7,=;(<?.B9#0!?7'%$/?"024G%6,*3GGD1*?*&;HH#9H;%-1,7/1BAEH,/8&F$=<A#;>35-B2H+69/,9$8A)"D+9-A&-?=5@'9&)55H;<$<DG*)G7A#7@=6EHA)5*41?C'8.*BD3G"5)(<4:D&-()F2-9A2>';G*;9"H8>-D9"5)2@9(A,+1.?5A&A3;8!:4%
@r4545
CGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCANCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAAAGCTTCTTCAGAA
+
,2.!)$82C"F.'45E-%4+FE4$<2CB#G0G=AB$AC>7D4$E)H/F*C415/1*3=+?7:;!/#9'%+36C@1+&#9.+<BE61-1?%A4$+%5(#0>+6?"!8B)DG<?E.!CE+$:6A@<.D=</B%0%C5=@'95B=5)G-?&#G5A=>:E/=5@=C2@!G8CB?GE$(6&H2
@r4546
TTCTATGAGTTACCCTGATGNTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTATGTCACTGTCAGGAAAGNGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATGGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAG
+
<;,;FC&#2@*8%">("6GE6<"(34)/*746=26$%)4&-+50&DB.7:((7>%3(@&B&F69>='B$>A5+)3:#+A.G*E3@%"71H<F==*,0.:;7#AD>B13&!2H!3CF!$#C5F#6B?0/6:%GD4%B=/0FG#%3?11.#7!$0EB<.<=%:AB41!).->"3*@.#(/C)?0H3=,8/75:#>G*>AB.5)/7#)B43=CF:!$,!"&G9G:'.12(A39%3)F93@G+"9.</18,,.>)1<2%90F/%D?$/(0A?,H1;@@6&A7/;)EG8E(+7:@03+F#@1CBGE"FEF@:?=CH"<H5@,+#G@A*"F3*!+E%,DCF*-74%-+CC?G34
@r4547
NGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACANGCTGCTGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATT
+
#B?D0@4F(-4+D4%CH5*2A<$/:;HH>*;>6/8+%,5!G70.7*".E>C#H4:*440#)8B$>2'0?9<7CC0@F487/C1/:AC2*'C3+,(EB(C/-H=/+623'.6F&,;F$5<&1++*&,G:!!'G84&!D7(-7-7-)?7&*?8FGFH)A!D08A4%H3F3H8?/C348H!(>;5/9.6DF>0A)9
@r4548
GCTGGACTATCGAAGAGTGCAAGGCGNTCAAGGCAGAGTN
+
:868H&DHC-+@*D%632::$B<,3GF'<=1H;<6672;C
@r4549
TNCGTGAGGANNNCATAGTGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAANAGTACCGATNTTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGANGAGGCATCGTGGCATCTCGTTG
+
#)!'%(')"$!!+*"%%+"%&+!"&)&!'*&%!!%+'$!('(%(&!(""!%*'%%*%%!%$#)*)(&%!&&!)+"!(''""(%*&()*$&#%+)%()&"!(!"&'"))$$!+'"$"&#*'$%)'#$'+*)$+$'")(!*&($&!"#("$%"+&"$"(*#(("!+(*'*(+()++&#(*&%"#('&)%%**#*+)"*+$!%*+(!#!!*$'#*(!%%%)&(%+
@r4550
GCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTNTCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCTAATAAGGGTGTTGCGCTNCTTA
+
B!"'61?$/":A'&8C"=.7B7FA2+,94A6$7<98((#G)@G&D8%;0.7A6+6A>&%4!(?!*H0>#=2C-*055,D2+:'(9D15F.H/+;7D&F/&@D<'5G1?8)@,"//FEE6E2>=&(<A!124(;A$D92D%2<F%2$?('/#=FG#0C.50?%#H5H'5!B6!:F<?E)
@r4551
TGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCAGACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTCAATAGCCGACGCCNTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCT
+
0&6<E40,=&G!B)4'DH.)"6H+3,?(9%0*H=';1>:!5.HDB!)9B98H$>=+C8>$+F2ABB#"9*F4(5<B.:9:;,:%F3C/-DDG,-7CE%C,#%5<E3?%G8A$.@#&0B8**.=%"7B71(A4D,1;@*".8=BA2--.D3B%+H3(=>45/!%A-0,+.(,&B-%5!"+34G#'<@=%"C12CD:;/H25;"*;,51%G*6CBF$C7$#8
@r4552
GCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCG
+
*8.EH#23D0+,>0G;;#)GD..A.?#5.+8820?F"/?&+7"G/E/)+/%(#"+!2/BH9").>*:-F/2"73*"!7=B4"
@r4553
AGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGGCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGNGCCGCCGCAATGGCCATTGGGGGCCAACCGCGTTGCTTCATCC
+
HA34,'10A'"</2?$3AF)<.D)7(=:4/#'7!CC=F'E-</#37",-;'F%A*C5A+E4>AH!>$":6B9EH63>H=+4&(G<.G&"A>0A@A"5"6#+:@6&%(3,=/'EBB7,1;$>3D.H"3+#"/F)&@$%?>E-150:@+C!/B;877?%>EA1#(-7'>.G:5+8.+96DD3A1//G<B6*@G308F#G=9A%H$5'+"768*GG/8)<G*3BH.;5>%'@#/#84,B2*E;4-H1
@r4554
CGAGCTGNNTNCTNTTNCGCCTGTTAGCNCGGCAACGTCCGGCGNACAN
+
&"'$(*&')&!)*&(&*+#&!%**')#*$&++'%$%('*'"$($'!)"'
@r4555
TCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGANNCTCTTCAT
+
1E=.89H1%()F;@5.*">G@5B7+-".2-.3E24;G?=(+)5>!+6>+%8=!::$$9!*+4#*>0$)2@869&%85'B*DH0(%?5'7G<.5,$!;01DECB2&.5H*5/@H:95,D@H$&$A
@r4556
TACGCATACTNTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGG
+
1E205+%=*+H+-.#2F!7CFF.D?/2-:4D3'7<8#,;4-'=:39G;$AF044
@r4557
TTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTT
+
=>0B%4)./8*;&$(!E8>F;&;B%"%:%?##:D'+)(<;GB0)55,9(A
@r4558
ATAAAACATTGTAACANAGGAATAGTCAGTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCA
+
:))%$3(4"&+/:8873*',!9.)4H)(-EE#AE17<EE)(,/6)%20!8?*0/-+(3>"(5F)?/59!/!A$
@r4559
GATATGAACAGATGTCAAACATCAAAAAATACATCATTGATT
+
/;8%78.=.)5C'2B*"AF:/>46)CB-7+7A48>6#3#-=)
@r4560
NCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATCCTC
+
.A2:!/7(+0B$F5<;G;8>FA200%2%.2,B)F@#;/F>.!D<&-)#F@62>F0$449:4@;1:G@//C/"8+2=D980>H&;G@*(=6D$C3?'CAF6#A/@(/$G$)'7>'E
@r4561
CTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTA
+
3A8H=A%;H<)!0,6*?@,.$7F9%G2$$%G9?$?-6<CA=/
@r4562
GCTCCAAGCTCAACNAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAA
+
)65A7&?AA@!#G!;#+:>.0C%;91#F=BF;6+(+55,;=3:;A5#';!D+.,DC$8,,/.7G%%()A+06B+$DH$%..6.=!=(<(.6B%#-6!0+'B;()
@r4563
CTAACACGATGTGAATATTATATGTGGCTAGNTAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCNCATAAATCTT
+
64637D&+48%."8&/H@=&",?G.)C(*2+82-%!6<'D0.A8(;#+5?AB5;>&;&;2?0G6"4<9/-@!E46(,=#E5C/1F8B"2;86*$1C
@r4564
CATNCGGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTC
+
(($)$$&++'%"%*!&+*%%"%&&!)("%%+(#*)(")#)%(+*$#&(!"$(!+*+$!#&#%!&
@r4565
NAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAANTTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCAATATTGCACCGCCAGATATTCCGGCTGGCTTTCTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTG
+
!9#55&,EAH/1$GE&>"/:798%3CHH1A&D<<BF,8!DC=&()9/'@E&=7-E3)1>3$/B=*$.H7,CD2'ADDH$G25*B13G0-'!(*,%DE3D+8"#)B!*D<A*3=88,50FCHH$<,*<@A/88%!?+'!4$H(8B=E=&E6FB@-B%4>-HD">*?B)=:,H@)!+>H05(*-H60$7*"4-E''73-A><,E%"?(>=.40%F-H@0$G!,6.&B!(94:%;5&C4"FH970D9,#;6;!/G7DAG1;@+?)
@r4566
ACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTANCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTC
+
&0EC%'@E+B?66$?%4%23#&C#";-"4=G#B7->!>,.&">":8"!-=G456,(1<&/%;/H;G64D@80/851A6#,!6A9==@?-H0<C(9;+,-+9"F;"@-
@r4567
TACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCNGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATTGTTCATCGCGGATGGAGTGTA
+
*@D,F!90:C;H"G4@FH*06:A-'-5/#D/>1&3%>('<(/04-7-4;F-.B1@+)@#/G#+1G0*3.<5@4,>#?2&!84"5':2%-$=1;,?3B13H''7$A@+>9F"))92"/+9E28%#!EA@B*.37303?,25E!EH3-&'H=+.B6<?)F)=$(0.5E:?B=.8$@43AE=1C44"4-!(9@.2#.45EH7,,A3;0:G$#/BG:%05BF<?3A$(@!5
@r4568
CTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTT
+
$H"E"H"CC6=C";"A;B>#(@+!';A"8)&E!;G73,*B*:8+$CHB>*%H<2#:D=%7)A=
@r4569
CTGNTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTA
+
+')!#($(*!'"*!%##"(("%%)+!)%++$!*$&"+&"!$##"!))$%#+)$+'"#$
@r4570
NAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATA
+
)@,<+:B/H8D?A",.+(2(G"?;-H--D/"%E<(-1*$8%&HG6<8<B@!%7
@r4571
TNCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGC
+
AE5.?GD76'#3B0<?$',6F/=>(G:A9&%2-HF($;"%D=F&-/"$./<E5?(1:76&*</?.'3.D-H29E=$G;=D6->H&<<&6)#"@=B>&)5D#*(A4)'!+*'):63%)B?1(C
@r4572
AGCNCGNATTTCNNAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCNCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCNACACTCCTTAAAGACCAGGTTCG
+
)(%!'(!%((()!$+"(!#)+*!(#(("'%!*+#((%"'()%!#$$&%"&)'$&%*$((!*#*#"'%)*'+'"'"&&&"(*%('"$"%&"+%'*%''&("($*'%')**(#!(%"%)**&&")(''!%)(!$$+($!*#%$*(+%#")#(+)+&*++"##++$+(%$$+!&*"%'#$"#&
@r4573
TNCGGTNATNANTTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGNCGCACTGACCACCATGAAGGTGACGCTC
+
)!"))'*%)$##)#+$!)#+!+*''##"(((%$*($$*$$'*%%$(!%!!)"*&#%&**(*&%"#"%$+%"+!'#$(*!%#"$#%%$#"!)&$$%'+&)"
@r4574
TGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGAC
+
23B/7HH*.?,D::!-):,5*F<A:5CA#'=/>H90%D7E.+AH&ED%$FF#F#;%G38GG#$D?
@r4575
GCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACC
+
A;;G&3H9%'E87F($9,%%&H$B1)E!4F0$44,.18D4:1(2"&!
@r4576
NAACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCNTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACNGGACATTATCCTGC
+
!#&(+*'&$(&!&$%*"%$%+"&##*#&!$'!"%'($"(+%"#$(%##"#$()(&)#*+#!"%'!(*%")!+$+*(&+#'%(#!(#%+!%!#%*%*#+'**##'#(#&)$*!#%!"(!#)*!$(#"#%'$'#!*%#+#%&)"*!"+''+)&$%'
@r4577
GTCCGGCGNCAGCCTGACTGCCCAGGAAGCACTCGCGACGCTGGNATTATCTGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCG
+
:$BA/8(E;@DF8(3/%+&""7#A)1"49<AD&9;=(6","=?<&7;6--!=9+5-#B'"*'-441F9#@2A;4.:+$F&9G:8=%*)+9$:GH!F!E',%2;89200/>9$>FH1.C%:B2-:1
@r4578
TCTGCTTAAGCAGGCAATGGTGGGGATTNTCGGGAGTATCGGCAGCGCCATTGGCG
+
D:("%8$1=C&GF":6*:-3$B@D&77&,9<-++7/)<C-*+0'1B7)AE'02'@$
@r4579
NNCCGCCNTAGCGAGTTCAGATAAAATNAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTAGAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAG
+
#$$*C/-%.84/28)@B+"9HF:.*"*G:)E77*=5<<F"?';$,/@=&:=#%A">8(F';2B*+@#CCD133FDEH.?!?#7F#";8#3%5D&"23#FCB&E1/-(1<E5"798:/,"@BA+%=1"-/51@"=A"%-'>9()1748
@r4580
TCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCNTTCG
+
(.01@1/#H:!.1'<#C<"5;&)7!=$.6B(?*3>A'9>293(5./>&@;F0?"C/#F90G-3:63H0<%D-%4'1#3://?"$H$BED!.')87G.54,
@r4581
AAGTTGTTTTACNGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCNGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCA
+
)?GG7H%.A#!)H(E%573>17A<1A&G1E:4.?F-H<),5>B22-:+-45;H<?-7<#+G$G7-=71=?.=*??#CE3*:&EC>==75543(($@%7:$>@(.?!H.#/2'B47?*<@@5?(<3C,:<D9':"=,G/1+!":6
@r4582
TATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCGCCAGTGCATCCANTACGGCTGCACGGAGTTCAGTATGTTTCATCGC
+
@,-?<CH?!6B?!(759D60+9C#B,'/.1#8@H.G:,4D/CH&+D!*AG.:1BBBE"A1";F=8418.83>");'+CC+H;=:)07:6H+<7(-D+HCG;3BA)+88"8*0B*$3&<&H8<"G42=#55@=#CA)0,03A;<>-D
@r4583
NNTGGCTATTCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCA
+
!"7/54E(D5">-02*?'5/"!?B%@!F$C:>*!4#,"BE>B3B65B%&:6%F=@#=/#"B-=F&C29GA"(D$9B;=7'&+"6;0<A.:2@.*?-F&;B#
@r4584
TATATTCATATAAAATNGATGGAAAAACTTTTCTCTTTACCANAACAAATNACAAGAGTCTGGTTCAGAAGATAAATCGCNCTAAAGCTTCNGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATC
+
<0GE9%GC1B)7-#$?&'=FB8;ED=#8E-2:+=!)?7993;;)(8<%,6&GC':&?29BBBE?83C>F?;A,=&"%5918&-E%97&H=?.>A+,9B!0+/C>32B/(63=8!$5,;99'8C;6'.-*'
@r4585
NGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCNGCNCACNGGGTATTGCTTATTT
+
#+*&+''&'%)"#)!+#"%+(!"+))')"'$+$%(#&%#*$$+)*)&))++$&'#)!"!&*)*
@r4586
NGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGNCTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCAT
+
+/!5A3H<#3,.H>-*)&#H9'%H7+AF+,:*.FG;1A-BC-.%7F?"=8%<;#0.D"H19A;1..*820*/0GE7EA3H+178<,?$H=*3:''2F))#7$;+55,,C<07**
@r4587
GGGATGGANGAGAGTATCTGTTCCNCGAATCAGCGGTAAACGTTNACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCNGGNT
+
!,6<G.;=>(CB<8@.33A0?6.2%)87"95--HF/H,A>51%58F#.G7H1FCH54940($@'#,>+:896'H,BH6D8=.F98-F*E?<(>G31<8477DE--'A.80.G@)9-G'&6B>>
@r4588
TCGCTGAGAATAGCCNTGACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCANCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACAT
+
895?8;*//B/$<:@*(><$78A'/B--;98E3:70"8!!5<D2#:$A$G2%9"08768;78D104@.9BF9"&>F%74)-.,01.7+>81C/6E#E)D',(?BC*&>@("5'>>'H5C8@)&(-<!H4?5E?84!DD+%A)%-%@1&G+(&A?0C52?(%FC0,1D;'@()25BA!3$2,C@G0>?67=61#+5A<8$/1G>9B+*18"@3:*:F05>F7$GA*14+$%<",7$A'D<@?;D=838.?<9+..C1>FC4>-%<B.5#F0#125$'04A3C17;)0)%D%+7@81+<(D,+GFC)2A
@r4589
CTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGNAGCGACATGGTTTGTTNT
+
3$(E*92)=":!5?CG?<"C(7";@.#CEC!3$6.CG=H9"F&+(>A/%'C;$29'/;0-C2H;!>8*A3C3.4!+%/%-G-$D.'>+:E9
@r4590
TGAGAGTGAGCTGGATACGCAGTCAGCGATNGATTTTATTCTGGGCGCGAACAGGCAGGAGCAGCGGGAAAAGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGCTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATNCGGATAACGGCTACTCCGTGTTNGAGCAGTCACTGCTGCGGTATATCGCTGCCAGGCTGGGTGT
+
;0%G2'>?3!-*HB7'"F,6+%-H)E+2'!/F>)<!=!@>52)?D')C:"-)48-,5G?C?,D;>5*0(56DC*C9#%;(2;;/*$G$!=/(A9:97;FBB'=.DA.:F!B#F#G*70;<9='F$&A8?H-.9@2#%#3:::3@!>@595="F)0/4:=E(0>.?H2?=37<E1:&/*C?9H>HGA$!59+#3>89<G420>'$!F9(*%,3F-.$:?"8=$.->$:52#>E$:"')=9026+F!A&+6B!&,5*:/
@r4591
CAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCNGAATACAGCGTAT
+
C"+/-:908E;#%9A3(2B57F?@(.F!?E+E"C&F4;+:H19"7:FGH(/%B38?-1,+<=!29C!C,!8D7#;0@
@r4592
AATNANCAANTGTATCAGCCACTGCTTCGNAGGCTGACGTTACTGTCGTGGNGCCAGCGACGG
+
)'*%)#+(!+"+!)*&*%%($#$"&'$!+(!+&'%%"'!**(*+*(#&"'&)#)*$$#$$!"$
@r4593
ACCNATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTA
+
('%"*+)+"")#&*%###"#"#+#'*!#($)*%#$$+%"')"!*+$!#($(%
@r4594
TGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGANTGACCGNAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCTATGCGCG
+
5$!.;2:5;5D8!.B@$93,,)?;6&C>*"B6>(;+71$G:0>6,+A/G&69668</7E.-B#8=*!(><('"D7/#+$6H1#9A+4)#!C0%)%CCG/0(;!A5@G4HA%C@12E8A
@r4595
TAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATNCTCAGCTTTAC
+
!6>=BE36(20$.4%H.!.';))$"';&(&39&<;'3;#$9?1789;1=,'>8A=F6)7&"7&A.&&)#)3F"6*!,F9DHBE"A+$?AF:3@!:/,E(A
@r4596
GTGGCCAGTGCCCGGATGGATTCAGNCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAG
+
&>;E%=$';DE4@3!<D4'@,AA1(=!76"C.8G<=C+B/<=-.)!/>8$"$7.C-/D38G.=?;)8C2&14'8+4=<06"5$&0%-"H&-@B9$CC588):@(/B(8!9"B!*GG,0143'0=@12H-(%%,:!-5#:%B18F#"(F)66D%*85.@81(H,D(.$E6)#'%?.,*F39@<?/$DFG40%;3%E(&F/=6ED@('15-7E3F<8,"B'@.").)B85H#<)/*,-;),5=E=;HA,>4@
@r4597
GTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGNCGAAATCGAATCAAAC
+
?G>H"':6#%=,8@:G*/30.$;('%;*@C%1(&0-D44FG?DA)-/C!A,&+7
@r4598
TTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGG
+
C-%(--."!/>4>BH%9@H,6)H#1C>)?;GBB#+F9F/+$,DA<7'G%%=0B3,'7GFF)<E$4
@r4599
AAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTAC
+
F)%*"G+!HC'-<A3-A>0#>6)3/8'EF0H#'*;E:91')2)A+5$=9*1A;"&@F8?+<F
@r4600
GCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATNCTGGCGNGGT
+
B==7A>%$"9='D!0GD+@B<:8$2*&*$;?CB%6HF'14!F>&B?G<DC$<86:;$G@.5/1530..E4"";E/422,#;#+=79'4:/,;C2/=0.,<%H,5%94/,C'5&CD:>B#&H#0;,$2&8:!2G8E/8&0/@G1
@r4601
TTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCNGGCGCTCCTGATACGTAACCTNGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGAATTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTN
+
@4('"G2%,)B+"B56/+,D@<H,DF(=AB@=80.B1D0H<5<>E<<(19*@#@6CB2>B:$(3H3%*+3B04;D#>?GH&C>2(;:6*'5@<>9"/!-59F7&;$0EA4#(.F44<$-2<B/:.3'A*;0?H'G/"%7'CD?6.H><ECB=;@>,@6'*6#6<A2::
@r4602
CACCATATTCCTGAACAACTGAGCAAACGAGAGANGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGNGGATTTACAACGATTTGGTCGCCGCATCGACCTTCG
+
;!@'!;B!E-*!;EC)CA";C%?&,D"H#<BD=?C"444?2':,4=.3;&=:G<8HC">BG%(>%#0<.=G'H$.38!">A2&C+-62&6E/"G/E'A;$D&);'A9AH$=(&..@&85B><?><<5)!:$.!)2>"<9F=&16=
@r4603
GCNCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGAGCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGT
+
$'("+#(#**%&'&$&+%*)#+)"&$&$'#'#$(("*)*#!!#)'$(&')'&&'+(*%"&+!&%%()&(#'"!%!"%('*')"+)#&%)$)$*
@r4604
CNCGGTGGTGTGGCGCAGANGCTGGCACCGAAAGCCAGAACTCNCCGTATACAGACAACGGATAACGNTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTG
+
#!A!.1D>-2-4@>64B$"B(4./>5?F95B2F36F"AA.4A()B$<6.2/+"C/2;/;>&,=@/"2(,B+&%CF>8H6-=4E6E5A3=7<:-6.7":7H?D,,)6;"F%>;;<4!:(2H4-D5#(
@r4605
TTCNATGNAATGTNTNGACCAGCGNTTTCCNCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAANGAATGGGCATGAGCACC
+
**$!'"&$%(%"$#)!%#!"""$%#$(%''($)*#+!)!+#)+"%&(#+$&*!$#&%*'"+%)+!"%&'*$&%#*!(&'!+"''!)!*!'$#&##$$*)&%
@r4606
TTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGC
+
+*'%+%"!"*%#'%&((%"+!$&#$)"#"(#)!$!!+")"&("%')$
@r4607
AGATTTCAGTGTATGACNACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACNGCGAG
+
#;=7/80;)0=%&#-8DG((6<()B$+76.*2@2=D@9B5(4#<CE*BE"1:>:-1F4.G9.3*G18%8&&F=';-"4F1@;?2.0.-%#3H89A1?31%+EC8:.#5%74%47AF$HH)%F4-<7AE2'G'<<A!>
@r4608
ATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTC
+
@$-5"!C.C*6::3:E$H.+/C>066A".59%<7!"#A7EH"CDC"G4;3>E22680:+.<<8?%:G!(
@r4609
GCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGC
+
65A97>5;&@FF!0(&'#FH=G>3>E<24:9F&;D6;!!;9?70:@@$62CHB>D5+%'#7H,7=!D3
@r4610
GAAAATAATGGGTACTGTNAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCNCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGT
+
;+5A795&$*#!DD=HH)A:49@F5&E*&E%*+9?;69<+#HD:D/;A3;)/7*:32>;0/$'?*;'%2<-E'&A=07GG<@>1>"C+169?#!*>H&A:"D=B-F&9-<D,0/26"C%+7&&0>=5&D#1)4683/@E;B!5"++!6<9GF-#3$9
@r4611
GTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCT
+
GD,9D-6H<@,-E35#->.=&/E&.<6%*9$7H$D):G<7?&)65"
@r4612
TGAANANNGTGNNNANAAAATCAGANTTGGGGTGCCGCAGCAGTTGTCCGGTAGTGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGC
+
)&''!$*&"!*%*$'#**'''#$))!+'!$#'%)"&+*+'!')+&!%'")"&$($')('+)%)&*'+)+%)"&"&%'&+")&"+)"')'"#)+#)%$)+'#!$&#$()(+%"&%*#'+##$&"(&"##++''(#(!(*!*+"$)+#*'*+'*
@r4613
CCTTTGATTTCTTTCACGATCCCGTTNTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCA
+
F7A>90'4-0?>F1BB2"*78AE-//B&;?#:9&@!+=''@484(D"EH.84).D65B189,3;B*>8FH737B*54/B!>6BCC,H
@r4614
ATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGT
+
7C?'F468)*<+&1!9/.*D066'4D.)')*94.9F)7;44
@r4615
NCTNGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACG
+
$""'!)))*#&+&&*)*)!&"#&&"'+"&'%$+$#&*)%)+)%+!"$
@r4616
NAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTT
+
(,#4#A-;/%43FA?$(1<=&@=H;$<,+#*:1%+/28)7;3@:=8%H8H/>A;=D5$$;1'A'FE!8&(FG?1
@r4617
GGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCANCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGNGGCCACGNTACNGGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCNGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACGCGTGCGGAG
+
6&+0E"F.&'>.E30$7:(-=9)'>?57B(;0>$65F(;3/H#7=&:7/H+,5CD@:F0H4B%!7!F1;E;9F<1#<9,==H&%;&&.AC0A5+.*38<,7?B;8;?6=<3':-)B4/EF"&B*B5);;#H<&<;>!?/?A'53-*63&1@C-HH#4-1<6$D*F#-6"CB;$!D1:C)@:A.10'+)?8487H,&@:4957?H!?9B;%&0)-$!#B*(5591#!8(0*1:,'E!-B/"%9>'6>23!705C31?D764(7F2BCE;)E+<B($G(C!,0"<*$;3.<9F:?;**)#>9(-)058%B%7".#@".3?F-(+*?/1#02H0H*.C;';!4/
@r4618
NAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATA
+
$/'#)9'!H<AH(>:A3G=AB-.FEH3=;@2*G"84"138#,BA.=FCD5$2:80F5+$=<2,77"5<#CEF.93GGH6<9@G:=&%&++<8
@r4619
TCCNGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTT
+
/554"%",6HF5&@+EA:=+(85.8,%/09!,G+D)!?"A74,-5+5?:46B>AAF@;*C*>!((:'/&;E>&F.9GD#;7:B.$G1<FA=?&'
@r4620
GTCCCTGTAGCAGTNATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCCAAAGGCCACCTGTTACTGGTCGATTTAAGNCAACNTTTACCGCTGATTC
+
3/B5-#B.2)C'2D*G?8H$=<1)$>"6A-51:#?G,.4&?D?17,E<9@+#81G%8'?40/<C?)7'905.*4/EA0-9GBH%'::3!<1:$?A!A#15&10-D)(95G#+#647+%*"25-B""90(94-*7+*(G+9FG?4HG7<
@r4621
TTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTG
+
9'/E.G$3B<3E$H'%4310?=9(C;B"4+$B#=#961%.4-'<D)!8(*D'B;;272'5H;=.@:0!%89>!H58@1B/'5/=A"!4-6H&-#&..7':-&/D.F/F&5A5EF5)E%.?;6+,*!%+46FC-:+)3'2A2(9D&)!*1,9+8F=,&=D=!',%81?*F3840H=,42%?5@9H;4#34<GA$>.
@r4622
AACCATTTGCATACATTCAATCAATTGTTATCTAANGAAATACTTA
+
G(D/%@6&A2;3=C.+C15*<>F+HF,*=#BBC72F-0(.H5$%!>
@r4623
NTNANAACGNAANGCGATACGGGAAAACGGAAAACCTTCGTAAACACCTCGCTCGCTNAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGAT
+
"*!)!&(*&#')$*$(+!'(*$#!'&"#'$'+%&"**#!'(#'+!'#"+")"#!&!!+!*&%"#%$'"!#!#&%$*%#$&"*)$()))##!*$
@r4624
ATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGTGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCC
+
:':!$<D@1D?0"$$41(&?--D)#==A2(92*8E5-AHAB"10G.<76%4'81?<%C($6.-,;"-FG9E1A&7#BG?HD,%D='
@r4625
CCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCANCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCAATT
+
@D$),8*C<5<?H"?#'-A+>5)A';.D(:,+D&/:!.8=,G09$95/)E2;>$+<-8+)%.2ACB2.?A6(1<FH!$C9B/'=+-;67,)B0+7#AG+:9%=&,'%0)%=?68=+.?32*/D72(('0;E?H8(+'C-H":B@>/1-3?DDED-0:0/4G.G.9A(//:A#'=,"#8$23/B';>-(=6:11D3+E9:#&1$)>>'=%FBD@5
@r4626
TTGTATCTATTAATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGNCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTG
+
++"'!(!""%'#!)*&'"'&!!**&$%+%#+(!&%&+'%*#$()+&"!!"#$+$!*$"*$""#&$+*$&#%++"$'+(+'&'!"*$%'%%%"*((+&!"&!&('
@r4627
CCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTG
+
7&+&7E&<2#+48;+(6GH42#1!>;!7%?:G5"+%9;B**<:E7.>:C!B,!<84=HBD2C/2+'%FB:5,;$9&&<.>629%7#F(@!G@4:62!(F+5<C<*3)2H!-?$6B&++;/6#%)&?!)578DA:82$G/))?:50$.>>(FB+?,G1,0''10D%0CB&,9%><B)%2*'+
@r4628
GGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGT
+
@;%/!(G@."GD@<F?C2!G8<7GB@59@2@19!-A9?4$)$%',&(76$9&50*60/7<1DB35.?+7
@r4629
TTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGA
+
>CC(5*G8:-=4!9@%H'80(C6:C,7>270;*$>/!2A8.>:0?(-#3#@.FH3#G7.9<AEBAFE(G=)?A!HE>"C58HAG3%E@"))/D7HBH59>1.E9&?A&D*09:&2,/F8&'>,G;:(89+H,$5-4D(:'7$GED1$EFA@:/<F<>*&3F$;'*CC("$9>08)G8;-DEEH0)0'<1*D0
@r4630
TTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCC
+
C,FG=HHD'%$@:&HA6H"D6GC?--$)H!?)"G(2%3!9%2:G:%9B*-71*A,C'<6#9:(3>2%38"67C%H#HC!5A9!4/
@r4631
TGCCGTTCATGATCTGATAACTGCGGGCNTNTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCNCCGGACACCGCATCCGTCAGGCTGCTGATCCCA
+
:8*5/7&'BE,)F.@*($&=52@691('#FF08HB6A).9;#$@,#D5%)7:A?A+2/CC0!*68B.$0;B$=+5E55$;+;!:#7*;G52?92C"GH5:DA04AB*')675;$/-"1;G3AH3@4&7F/.
@r4632
TGCAGNAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGA
+
B3:*3C/91;"A@+"5/,:(,1>1%A-"&5!5#=6%>#>&'05</;+&B5*E'$*:2<C5/GG(8'&++/D':)>&>-9A$+(@.A%F7":6F2;"D
@r4633
GTAGNNANGNAGCANCGGGAAACGGTAACGCTGATGGGATTCACAGCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGAAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTAATATTCGCATTCACCCTCAAGCGTATTAANCAACAGTTCAAGGATTA
+
$$*!"***#(&('(%)&#+$$'"#!!%'+%%%#)#))!'!('"$))"%&$'#&%"(!%)!$)#*&"))+%$!()((%%!$*(!$(*&"((!#&&"'%'("!%)$'#&'%"+'"++((+!&"'!(*!*$+!'$$!+)$#&+"*'&%#&&$"(('&*)"(")&&)+)&$*"&')#'&"*+++%+$)'()#"(#)*
@r4634
AACGGAACGTGCCGGACTTGTAGAACATCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGTAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTCCAGCATCAGNGGGGTCATTGCAGGTGCTTTCGCACTCAATCCGTCGGGAGCGGTTGCGGTATG
+
D9G3#$7#AC3AH>%<?+<@<GA3@E1(C3(!!*&@-&?(*?26;')E12#5+7$1D6CD5B!?%H++*-91G!84@3&'41HB.=1!,+F9<,!>$D@8<:<A=2G790D@.DC8'CD++B-'=$5=F$!:#;B&91%3"81!F7#A-@)>)>1C!'H2#?'<'>1$9)*.BGF-D0.55@?HA8/B
@r4635
CAAAAGCGACGGGCAGGTAAAGACGTGCNTTACGTTTTCATGGA
+
!1>2HD(E+:1/F!E*1?+;5">4'9.6D&/G:!EB$$<(<4@/
@r4636
CTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTT
+
011A*><)CA-)=9/,!<4E,-4?)0A1$B.582)86#$F,6G3"&0%
@r4637
ACACAAATTCCGGGACTGGTAANCATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGG
+
!6#22?.A3/-B8#+=-B=$7"-!<510@F&*.$9A!=B>-98<9:9@#1$03@?9A%".B
@r4638
CCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCA
+
(>#EE!CE'5/'2:$@)*"4@:%D#9<=-$$GE/0AB05!4&,<,.50-";$)$$%A.*-13(B&4)%=13%H/"0-#.GFG
@r4639
ACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCNATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTTC
+
E5-A9*$%B5%7F$#C2/-G256(8G<$'<53?:F:*?;E?<'*47D,8<0-G/&).!"?C.,0=G1%4B2&6#82#7)!7.(!9@-G,@1'8$CE!/7C0(/:729"EC.=%&C0/;$87/8G;>&7?27=+D:H#3E:&8=403)D@D1$>AF@-<8B,%G.0):);+32&/'D".%:5%E2(7)6@F<++E@1@E0!>"C9/+6&4@7A<D#,84/!D;$&$D9=DCF4%7/FC'61
@r4640
AAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGNTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGCTAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGA
+
C!"F:0)"%=!0(G3;!2'G"(7?'?'A6A/F#A@E9-G00F0C*@:'F,6&DA118932=C)E@AGC)<2*B7F90:C"<B;A,&,#/*7B(@-4&0+9'G;H+FG/8$HA3/'*14&=D8$,A<+)+/)07B@85"%*<9;E-.E+GCBH+HD(H5;C6.750=!-A@00$,7(@:6#,E4BGD30G'9%F-5.71#40CG)&-DF*A:?")"'%!G92E%1'/9<&(-')A@@93";A(-20/+C&*!#&>1/G<38EE6;>12(!44(.'2#C.FD6!"3A"-%.A,2,@H(C5,GD+E6>),?678:+.+)&150=#"71"0+H)+1G'8*3&<F%4+013/@$9<8(%9!;&+)#(A#/
@r4641
NCATTTTTCCATTTTTCAATAACNTTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTATTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTC
+
!$+'%*%"%(+#''*+&')"!$&$#*%$+"#+)$(")"#&$$')%#&!&&$'$%%*#%!*$+++'!'+)'%%'*%*%"))"*#&!)#%*'!%+##))$&")!&))##'!#)#"$)#&%&%#"("+((*&(+)**!!(
@r4642
AACTTGGCTTATCCCAGGAATCTGTNGCANACAAGATGGG
+
('+")*'('*()'"&)*(*"'%!+'&++!"$+#)$'%$+%
@r4643
TATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATA
+
*;<;>$41*;-"/8"86H:>*A'):<88-7BC#(4?=89?;CA=(-6;#EA+E0&9;(4@)97&D$$>!8B$$C<&D%..F99/;:2390(GDH4/0%:3B=B(6#!BB=?.2#F"2.0#@G.=-G>=(26>;5&22&8.D-GC9*B$"?*68:7$7
@r4644
ATTCACTGTAGCTATACAGGCNAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACATTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGA
+
*"**(%&*+!%&'")#!+#"*)')''$''%("'$"+"*!('*(&!#*%#&*"&#$))(%$#++)*$#)(&())()"##(*($#"$("$$$&)##!"**!"%+#(&((+)($!**('))&(&#!((((#+$$$"**)*!'
@r4645
ATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCC
+
#96$:.G7<F635A'/>81=!3283H5B9%D."*4G!',+3>58GH(;678>$2753'C5"#"'?,#?A2FG&$2=*?DC.762,1B5!(@2DB(;<E!5;0*.@&>/)7HC@D&7691&&4A+=5=F-%@8><6%'$54/,$@0,'B=/?40AHD#=)B+%$?4B#5C2=8/-'6>D7@'.2C/
@r4646
TNNGATACGAGGGCGCGGTTTGCANTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATNTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTG
+
#'!+$'+%#'*("&+"*)'(&*$*))%)+**!&%&!*%"%!$(+)"%#(&$++*!+"&"&'%+!')%(''!&(%&+""+$'"%)!*"()*%&#+*$!""!*&$#(($"'"$!*!&!'(&%("$%&!*''")%#%""#$&*(%)$(+'$&($%)
@r4647
CTNCANNCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTNTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAGAGATGNGTAAGCACAACCAAAAAAGCCAGTGATTCTGNATTCTGGCTTGAGGTTGAAG
+
!'#&%!#%)(+*%&#)'"*&&!)"#'(*+'!)##&*!'(#*#+%$&+&("$&(%'$+'%(%#$&+#)$()%'!*+#"*%'##)&("$(!#$%&)"#%)('$++($"('$+&%)+$!!!''*')!"%&+#($*%+)"+'!)&+$)"&!($"+!#*#'%++'!"(#*)!+*)(*%++'#$#&")*+")*)$)#(*+%)%%!"#+**&+(+
@r4648
NNGNANTNTTNCNGNGNANNTCNNNNNCNCTNNANNNNANGNANGTNANACNTC
+
!"!#$!#!$!#!"$"$"$$!$$!"$$#"!"$$!!"!$"$"!$#!"$!$#$#!#!
@r4649
NGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCNGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGC
+
"'&/.;:;/;",8;1F<1.2@-B#2DG%$CA4"A<//?$GHD;8>,A6)0,;"(#A$F%C$:;$C*,8)93D</D!&F0A)%"6->1)"5!(2:9:)62E'C=!
@r4650
GCCGCCGGTCGGCCTCACTCAGCCAGGGNAGACCACCGGGGTGGCTGTGGA
+
:AG3>68/0>1/C*3383'5C@B$'/9/!(&;!+473%>4C*7337;(>5)
@r4651
AGGTTATNGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTATGTTACAGAGGTTCGTCCGGGAACGGGNGTTTTATTATAAAACAGTGAGAGGTGAACGANGCGTAAT
+
@=0D7#7/;67A696"6>;<16HC8+622-!()B-24(+G0$0(2F$7!&''#-,:92$FG;CC/E#'C;.%$6!%4)#A7A)';.(/HE:8%/1.#*:?<@-&"=F'2,&BC;3>2
@r4652
CNNTNNNNNNNATTCGATATNNACNGNNNCGTAANNGGANNNTGNNGNCAGGTANNANNNANCACNGGGNCNGAATNNATNTCNNGGNTANNNNNNGTCANGT
+
$"!"#"!!#"$#"!##$$$$"!"$!"#!"#$$#"!#!"#!$"!""##!!$$!!$#"$"#!$"!#""!"$!$#"#"$!$!"$"""!$$$!$#"!$""!$#"$"#
@r4653
NNAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGNTCAGCCAGTTACTGGCAACTTTCCCGGCGAG
+
"#%'))+*#((&"!#&"$('**#)#$**'%+%(!"#$)%+"(""#%#)'&(*&%#(+$*)!%")%'*!)%$%(+'+(*!#'$'(##)
@r4654
CACGATTGGTNTGGTTGGGTCTGGAAGGACTTGCTGTACTGCGTGAATAGCGTTTTGCTG
+
/>5>02(6)-C+4*7#-C3;A4-0.,G#;D;>$009:?A"0<?G4*->';,A<:A'<,-<
@r4655
CGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGAT
+
)8G10#!42!3AD$;5<&&E8-*H-.:!B9>)'A2?-0FAAA49:(*;;"8!<*'FH:*!625
@r4656
ACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACNCGGCGAACGATGGCCTCT
+
:@!$:";>&H-&#G=C<'+/&."9$?&&+E,*B5=0.&@)@(<%A6;GE+7$.&32C=<<?&A?$C#&19)&"%DE?2$$=<'+CE915(C<D(=)%<8+!>E#@1'(#??<:*=4,3#:7"1#E"&:4FC?&65*%(>/+D,'E?GE0".2'8&$9G9:GD:>/6(F$?2;+!(!:+$!7(-((
@r4657
GTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAA
+
'20*<E@1)<&/G)2'7(B=C*9G,+DE=97"14=6A"/3;$C'#0+C'C(A+
@r4658
ATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAA
+
11>8"534<,H7D!DE3&/2+G,,$:,G-'9@F9#=(59?,5(.2!C
@r4659
TNCANAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCNGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTNCTGACGACTCGCCCGCAGATACCTTCACGCTGGACTGTNTCGGCTTTTTCAGCGTCGCTTCATAATCCTTT
+
($#"$+#"*(")$&)$%"%)#+#+*#$%*")()*"*$+(&$*'''%+&&+($$*(!$+%'$!($"+$&#$$+)$("%))+'&'*'*&'%*!#!!'+'*''("&+")*'*#*()$")+"(&!("$(#+%$()(&*%!(%"$#$$'$!&$#('$)"$)!()$%))+$)*"&&$)*'#*%%)"!!%$&&(&$'*#!&#&'*$((+'%))'&$*%%)%%''!('%"###&((&#$)*+(*($'*&'!*%**+%$*'#$*('!"*#'()%%!&$''$#&#"'"""(()(*$')$+#$*"+#*(+$(!+)%*(#(!(($"%(&+))&!
@r4660
AGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCG
+
/HF=%/!&2!@#+(.??95=683/:A=!3:;-1,+#2:-&A"'<(>8>H53?B?57G$G010A'8E-
@r4661
ATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAANCACGAGTANAAAGCGCACTAANTCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTAT
+
D?(#%H(A9?*%!>'3<B?F6:;D5'E,).F6+-;F77,$/>619CHA&*,;4.#H$"7CC'A/$/2.'4+H@HB"6C7H+.-=.&87F-83.G=';)0#.+H%)8&$+A9;AE.&E>9C(A29-:@<?/;))G-$C&<"&C+(>,5.>4:B7F9C'(&"@C=('$#?F<A
@r4662
ANTAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGACTGCCGCGATGAAACGGGNATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTNCTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGA
+
*/!0/6,/.@?:E=#AA,2%$8B=+$C66E#**7F%G>1;(B3=$)22%*58:(:!.FDB:*F=?$C'H<!.%-8%?H1@:<7:F,.G9&5@%9&?AE/#$0&:@,/0ED=,?7-34)0./7BA&4<<D#1"03$?.G662()DBC&@(@D?"0?8H<++-8;<H25FH;BB@6G='*%D&,<:>+4"%)4!?DG6!B!821-A$:)8E@F.8"E7.A3D@6+2H!#GE%0G#7+>!-;4H6?=*86,'(!;D<::987!4/!9>%.+DA=C9*E(7-3FG?*2!ED/!;BB&D)5>*F,CAE;""?+7A2">FBG&**)8!29:9
@r4663
ATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATANGA
+
/AD><95<,.6=+6"&;3AA>A338*FG+$6@5&B<./<+"01%?
@r4664
CGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGCGATGGGGGCCGGGTGAGGAAAGCTGGCTGANTGACCGGGAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTNGATGAGGCCAT
+
"&+(&"#%)$%("&'+*!$!$!#%###$**&))))"(!"(!(("&++')#+$)+!&$'%)%#(#'$$)!(#')%&+$)#'#)%()#%!&$%#"*""(%'"!**&"%$(*&%+*""#&''&#%#+'(%++))&')*%")+))%*(+('&(*##!%+!+"%#+)"$%#"()"$("#"#!$*)##)+'&!%%+&*#&$$&'"(((
@r4665
GTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAG
+
BE4#86">,:.%?C"!!9+F21:>++/9)@+)28H3.$,+@/#&%(,6E;*'?3>"):3$/'.7.6>?"6)"4(#7ABA*G0%>@1,=H&77,/,6-!2!:%816ACH<6"/!F4'1E)?*9$!21F$1?"D6:/'1#,;C*!GA$47?,-B:9%1*E;C+=5)H,$9CC-/@B=:?4@F0?822D(3B=45B9=F5?9$?+..<489'&G;;9"3+'F$&%2:>/D4F1BD4!C'5)+>2-8#G:;F1>'@H?2C$#F/3%75F1:
@r4666
NGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTT
+
*F=8@?$-(1:H>!9*">>4C84/#&-/4+(H<.#*251A/<AFCB=)C0%2:!#/*00"A)@-;%(95
@r4667
ACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTG
+
2%2>6<+;3AF@H+CD64)$>1/'#E<$&296$;H0-7D3B<H%&1):FB-0(!%5?D0,$!A)H?(7<B
@r4668
ATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACT
+
&/;,/@+G7B*2?;8=+FH#65"#626H314+;,?+/99<E#";%<+#5@&@((F..#,:+:*=)47"?)$E?(:*H19#6&$$.*B6;F=A&9)%56'+4<7).$@7(DF!.:8
@r4669
ATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTANAAA
+
D5*,C)="9E7(,&E48;>C6%(<4%A1:15$3C+E*#'??70=0AG:B8'&:$#*?D6F;:<D:#
@r4670
NCTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGNCTAAATAGTTTGAATGATTAGCAG
+
#((:!*49.6*2-'532972A$D4=3-DA@1,)&>#&:2';D#:F/;398.0%1"(EB.>F8@4B/9
@r4671
GGCNCTTTGTCTCACGGGCAACCTGGGGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTG
+
#"!!/(!*)5HC3%+@?5%G6@C*<D.-2@A*E5E994"3H;;B1<6A9G2?.78>16><:-%7+@
@r4672
CACCTCNTAACGGTACTTCACGTTAATCGCTTTCNGATGACTCACACCGGTATCCCCGCCCGACAACGACGGC
+
41B&*'>+<)%!E4>;'@BB5H=@A&%A"%>D+=2@9+!3G76A(/H,29(-'!G23B,!A=4.*0%F#'AHD
@r4673
AGCTCCGCTANTNCGCCTNGACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCAT
+
('#*)&$*!%$)$*#$()!+'+#'**+$*!+*&"!+(+!!$*)$*&)#)!#*!($$"#$!)
@r4674
NNTCACTTGATAGAATGTATGCAAATGGTTCNTCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTNACCA
+
!#'"*!**+((&$!(&+(*&%!++$''!$%%**"!(*+*#$!"&&)(&*&$*#"!*+&)$!)#(**'*!!$(
@r4675
AAATGCATTCCGTGGTTGTCATACCNGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATNAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCT
+
9?EE1!>45!F'3D="$+"4A/B&6G0!)AH.E<*+%-=,,H34<H6.CDAC9,0%C>?.B:>3?(EH0CE.8;CB$'=4F8;/"/,56#,+*>0:&95A7<";1G;CB>!,>/+#%$@2?09"-"A0CD(1C7:?,<8$DC1F9?387>'97'?HH0FEBG+:GD0).*
@r4676
TGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGC
+
)23*&D+-9#*%DDD"D;6&236B7%<,=,#.H.?*./%9#0-@$69D4":29.B)+'57<B
@r4677
NCGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGG
+
!0*4'&"4"A)#71C@*(%;8?*()*C-G2>->,*745G!'!F1?FA'AA',&!C95F;!=$D#=,1A;7CH(6@6016%EG:;/@14D8?&2)F3,-.H.'*4&(/!C29DDF.&=!>GHH-=#%%B75'#A?)E-,D
@r4678
ANCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGTGAAAACNCGC
+
#!@-A8-88(0"7$36=E/F1G,&-,H>(;+@8":EAF/C'=HHG26';BG!/@4@$E89!@GG965,/0<?H<50E)+#575<9C=!GGG+B0H,9#/)G$E+7G9)>@'6;3BH
@r4679
TTTGTTCTATCAGTAATCGACCTTATTCCTAATNANANAGAGCAAATCCCCTTCTTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGCGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGATTTCG
+
+!+&%$%('+'#&&($"+*'!)%&%*+%$&$'%*#)+(#&*)+*$"'&!#*%!)#"'&!""!'"$)''#"'!$*!'*)"+('*"*!#!'#*$$##%')'&$)'(+*"#("&*($))%"%&"%"**$"%+("+'"#%!%&*%)'#+%#''#(*$%)*#%$*)"+!!%)$'%!$#""**)&'%)+(#*#&(%$%*$#+$)#'#"&*!%+)%''&$#"(')(()'&&+'&$&%'#+&*'*)$(&)&'"""!&+!*!!+#'*'+
@r4680
TTTTTCTGTAATGAGCAGAACGAAAAAGGTNAGCCGGTCANCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGG
+
#"$''(+*&)$++#$#!(*$'()(%*'#(!$&%+!"#"&"'*$()#+$&*(")*(#&'%#&)*!&%!'*)%%##&*&&%&#
@r4681
CGTTCATTAAATCGGAGTTGAGGGGCCGCAGCAGTTGNCCGGTAA
+
GFA-A#95%A,-+(9H%1C#7.;G%0*/@EBD0;9805-#$C<G,
@r4682
ATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAANAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAANTTAAACGATGCTGATTGCCG
+
B.*>.CE%1CB=@$D#7=5/)+*;@E?.<%??)1"&-6/',"=$E"4?6F">A"8+1H8A!*DE/G@0<H00>?-C);.<!-75%-&F15%EA9.2,-D!++>%(<2-%#E4'@
@r4683
CTGGTTCAGAAGATAACTCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAG
+
G922:69D)>=;6?3/1G,CD4@<;1+:/+/>C)A&-<,<B&$>?::#9C<1/
@r4684
NCCCATNGGCNTCNTTANTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTA
+
&$'("&$')$$#!%)%&+*+!!+"'%%+)$)+()+%&%!%#$&'(+)"!)%!(("''"$+"'!##$##"$++(&%"*#'++%#("'!%!(#'&+&(&#&""*&
@r4685
GGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGT
+
D91BH!EA,B4%@F4DE1-@<"09?'/9'2#663$3336A(0CE*0/2@)*H"-G
@r4686
GGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCANTGCCGGACGGCTTTGGCGGCACGGAGCCGCGGATCACCTGTAATGNGTACCTGACCACANAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAA
+
(7%.2!H=41%:767(6';$5;&5)H2!@!!-G74&&&>0A<1>EG33#?E0:1!62<.076.B)72D/@4CB5<>25856E,/#.G":5$>;:-;3"97?!/5'@*&56<H20=*#))&';<3+DH;;G'8"..=(2D/25>;6%,/=HE>(BB4>6"AD2'?-%H,!&59C<)0&F%G/E%<>2@693=&-4&+>%A/A(3;DB&5#A1.AA9";#9DE7(F0"B?3?7-,;7@2',>E6+DC:A)@>#.>60G/!G(CDH%E#*<%1='%81
@r4687
GNTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCAT
+
$#'"+#!*#**"*&##%"!(%''!'($%"%*$&'#!*#&*%$+#'$+'("*#!!*(&
@r4688
NGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGA
+
"77*51"F"326<=+0=:03;B7-"-G:1C"A46%23BH8
@r4689
CCTGACCGTGTGGCTTACCTGACCGCCGGTANCGACTCCNAGCTGGACCGCTACGAAATGCGCGTATGGGGACGGGGGCCGGGTGAGGAGAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGNTGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACC
+
5.%:@$CD%7H?4@409#CB+*$2D01?'H)/#17>#D!A+1/=3D)1.#$G5C$*;G70@F8/8/??A!D:A0'2,@<,3'HB594*?47A1..*.A!=&.($'%A>*;"139A(4@>)+9<?,6+#.;A@/"!@/6-4E5.@4,?;4D$+6F8#4B$+3(;/%?=0%DC#$<6<?&/""*A9+@F=&=4!CE59%@A)31C=<B0%=:%0D5-'?'9=C*G20C'34-H:,9$1>B;=1FAA"*:@&1
@r4690
CCGNNCNNTNCTGCNCNAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTNTGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCT
+
$%*!$%'!*!(&)*$($%+$(!+'&()*"'%*"&*!)*""$#+$$$#!%'+#%#('"&#)!+()$$)!##%#$##(%('$"$#!%'$'+#*#")(!)"#)#)(+()$!+%+%&#'+'(*'#!*"$)*%$&!##'$!$!#%)
@r4691
GTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACANAGANAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGC
+
'F)(,3C>7E=$+(H:@,C><8D&!=D1A68H:?@&H)C/:(03**;12+A1<#:C+3H"$:.-0;:<--""(1D:A/92<A62;*%$,;*EE48,9'H?3)71+44$3+4*A1'"E;.>!C1:#ABA?/6?;>3.=G/$/;B0G)1,)+*-;4'*D*'A5@5FD(EE;A<7>2@,7*,;B(6B/6,#73E7#2?H:9G,#/.813A=();&.A78")34"-%-<?0C2.8GH78"&7
@r4692
ACGGCAATNTGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGA
+
)'+'($%$+"%+#&!('#&'*&$#")#*)"*")"$(%"&)**+%"'')*+'+!*!#"
@r4693
CACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTT
+
C$C3>7H$*1:;B@FH=971<!((3;7"!H1*)#H92259C;+@=@B
@r4694
TTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAGCCGCC
+
A0GC159.5<BGE)&0BGA*C(,/?'1>?''H@-G2*4<;><E@G1
@r4695
ACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTG
+
-)9*:%>F)"68+!((!;&%-?5B$239E13&G>>#+;=D<21A;@>6=!%/?@-E'F%#2:?E0$//H/2G'!'('36&9"!6)&-.;F>'"906327$)'"4$0H:,/0B3@%EF
@r4696
CAGTGTACAGCGGTCAGGAGGCCNTTGATGCCGGACTGGCGGATGAACTTGTTAACAGCACCGATGCGATCACCTTC
+
")='>4,7E&@:E61;-&"E4C#6=G1467#%C00;4C5C!H-C&;)C(=<=F,/36C)A9'DG7;#BH!$(2*>65
@r4697
GCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGAT
+
'5!"2G7:<%F,$DE5,%B%,;>.A;F:#G>H;E9?.)@94$
@r4698
CNACCCAAATATTTCGGTATTGGCTGCCAAATTCAATTTTT
+
7F0/E*'+F"A*3F,?"(C'367=D%"@;D598!#?##*77
@r4699
AAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAANCGGCCCGCCGCATTCTGGCCGCAGCACCAAAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCG
+
464:9086:A+$43$3GB6&3'$,3/F>;2E-!D5-'BDB:("F#?40)6;7,-4G))$2E!/8E2D07B820H)-+(?9A$!,:0G$27)B$:?%H"9218#">>53"#*0+6#AA=-4CA:?/<6D,)*-+,=9=@,F3>C.>+(3-A%&*;H:(:B/'CC,7+91>3-B8>:&FD#61&=/
@r4700
ANCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATNCCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGNGTCATCGCCATTGCTCGCCAAATACAAAACCAATTTCAGCCAGTGCCTCGT
+
)+*"!'''!''+(%)*%)+'&(+&#"')!))!)%++%%+!##%)(%)*#$&'%$$#+%)$'!+&%!!###*+#)+'"$*)'&&"%#)$#&'+((*"&"&%)%!*+)#!$$)""(*'%+)'##!&"%(#*+&&$"(+*+(*$*#%'*#$"*++''+'##"(%&))$)'(+%"&)&*#$+$%$"&"$%"((+)!())!'!++(!$"(('(''%$&&+$$"$)"+%+)#"'*(#!+%"+$(
@r4701
CAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGA
+
GD7;E1'7H=)+;(F77',@,%+;*F7/E&<GD)>=6#&=G%3H1)A90?$F30$$G*302/+=++6//>:*&>6%)$#3<E7$,
@r4702
GATGCGGTGAACTTCGNCAACGGAAACAGTTACGCCGATCCGGAGCNGGAGGTGATCAGCCGCTGGC
+
)+")%!'&**!*!*#%&+'+$'%$#"!$$+&$"%)+&#$"""!+"!*($%*)*")#%(+#'"#(%()
@r4703
GCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTG
+
>HHA.6D>#9FA0F"E"9D%#40!1D:E/@9?5FH6,A!3F6HH71EC,=!)6H?+>6!H/0&;:5.A5A04,%'@.-<3,7.F6#3"/-"!2C9D
@r4704
NNCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACG
+
"&+)&%$+""*)$##)'&#$%$*!(#'%(!*%#"+'&%))#&+#&'%!$#$'%)(!+&%+
@r4705
TTTCTGCGGTCAGGTACTGCACCGCTGGCGGCGTGACACCATTCA
+
-);:*-B38E73D06,:'($/1%77DHF,@!97/'"6G!8+DH57
@r4706
GCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCNACCCCGGTGGTCTGCCCTGGCNGAGTGAGGCCGACCGGCGGCTGCAGGT
+
=/#,6A0B#)88+)**&@E&E6B",F5601F1;6?("/&&D/)C&:3B<0C,:&)DG365DE71B07%">H!B!?)BB"66G-5.(>D9,(B0
@r4707
CTTTTGAAGAGGATCAGAAATGGGAAGCAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATA
+
';8'18)%G?B)32:##:-H&,"G&A4EB?13H5A;=5G7F.'0$/5F?*;B")4CD@2$8(1H(8>F<!*C0
@r4708
AATGCAAACNGCGCCCTCGTATCACATNGAAGGTTTTACCAATGGCTCACGTTGCCATTTTTAAAGAA
+
-3;AA$:/9$%(F->=!?"G<904,;B!0#E$D>:5.7F""28-&:F-C5:-2G%=#/BF)8%>%7:=
@r4709
ATTCAANATAAAAACTGATANCACCCGGAGTTCCGGAAACGAAATTTGCATATAC
+
0!BH>=#-#B&!"2&6%*(B=C%F$B'07A++),..@;3DF;+B?;#07C-<@G'
@r4710
TTTTCCATGTCGTCTGCNAGTTCTGCCTCTTTCTCTTCACGGGCGAGCT
+
01&)$0#7#%A6!"@-;ECC.-7)?'F78&>+)C6:(2@>5742E!$&0
@r4711
GATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCAC
+
-,/D28G>/@#7A!>#"4@2%=3"";)D,=1E*=!;*B@;@AF:7,E:/D#8)+07!"/
@r4712
TTAAGCTNTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCNTCTTACGGTNATCCATTGTACTG
+
$)'"%$)!*%+!!&$()*$#%%&*$&"#$(*&#++$(&"!(+""+!"*%$$%&!$$(*&%!&*&()")#()("'%"%+*"#"$!$!!&(&!'!))'(+$"$$%!#(*""%&)*)%%%!*'!+!
@r4713
ACCNTACGNTTAATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCNCCGGGGCGTTGGCATAATGCAATACGTNTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACNTTAATAAATATTAANA
+
()"!)#*'#)&"+""&&'$"!&""&)&($%%#%+((%(**#+&'*"(!+&)!**+"#*(#*(!')(!!+"($)&+!++)&($$""'"(+$$#''&'%)!+"+&$&"*$%#+"&)*%%+*%#()#%+++(!(+"++(%*"%**%&&$")*'%")"")$!*)'+++&%("#&$$&$'$"*'&+&#!)!#!%+")&'&'!""*"!%#("&*!$())'%+(""*%'+'$#'$)("$**!"(%%!+&+%*)+*")))"&&))(%&#""$+)+#)*$*
@r4714
TGAAGTGGCGGCCTCTGACGCTTTCGGGGCCGCGGTGGAGGCAG
+
F)+G>AC;E0>E+*B0?/#!$=0;51'$A*+E9?B6!,><<!,,
@r4715
ACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTG
+
=;3822?"451?>*$-'HD9'FF%$)($)',A6)&;904):-#),>8,:B!:-?+0+C3G,-(-F/<#B*,:33:A#<?E,C)#&+=9EA,A:-4A"=<7139%7?9,C+?%G62)EDB;:*0D><1&E/+$#--4)F+->1!?"1,-E1#?;/7B*;-.9AG+?=+7$:&<H!:111>;(&2H:;<-72&3:7D)
@r4716
GTCGCTGCCCATCGCATTCATGATGGCCCGATGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAG
+
11"@A:,D)?13EG!4+4#)">!D&9(7GGF;1A:8D5;3.;-720:568>.@:-.0:%#'>,!426H/"15@50,=0/)#@G3H0#=A
@r4717
TCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCNCAGCA
+
+G&)&:+#%D=H5&,=<@0:<0*B+8G-"@A7$E<6#(4%&5,=8"FH,33+#-CG(B1D='(F/*/=3;D?)#!FCA+E@34#74,,E)DEH,:D!F0?C!"36=:<CE+76F@+:2+3"FHG;+?:,19$8E//=%3'*H8#;EA#:
@r4718
NGGNTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGC
+
$*"!+(&%)"'+"*'&"'"%)$#"(!!'%$!*$""&'!&'$"$"+)!"
@r4719
NAAGTAATAATCATGGCCCGGTTTGATATTGATACTGNCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGN
+
"3&6E*F7E<''F2@"401F7G,7B,6<<>/>01?=>:=%@6G@4H,9(.2B=<80!.)H!39HD$/7!!55F9%&>#2")$1.0-D;($!')@<!0!E!4>,D;=D'%*4D0C/1)1-F34<"H4"08;(E>G+B
@r4720
CGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCAC
+
D+#4F8?B3A4#/6+*':@EHA005?F2=5E0H(.%F7?$*E.;49/.&5<6;-#BA7E;1A1C6/DA$!DCC0$D(#%"&/*9H0$./=H4134C2!:/G*
@r4721
CCGCCACGACGATGAACAGACGCTGCTGCGTNTGGATGAGGCCATCAATAAAACCTATANCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAANAACATGGGCTGTTCCGGGTGA
+
69!;.)76A>;9$1%-7G6B08#D+1?-2/:4?$:8E>@>636-?F9:1&="F4(2H5<(@%5)<<@$(%5GE:7&&G:D.?C7B7=:<B69:C:/1#9*%;D03-#19G27C4.=6/G)9AA>DBE':)G6GA<)1=-/!!D7/A84@*3?0$71EF)/B*+>#".'9F'
@r4722
TCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGNCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGNTCCGGCNGTGGCGACTGGCG
+
;+8-=?6(0!1DC*;A:.&@88+13A$&!,;:>)A+HE5!>!?&?02=.-//%!&@:<G?,/3?6%11-*7.!!4+%"1F9*-GGG.*+4*A
@r4723
ACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTT
+
6>6'0H5H!5+C(!6D:'EC"-"+*.BC%!DA20$@>2*HD#5FG)-HB/73<?7;@3F,+&#5A/05H,6=BFF?9/A$<</G7B+@%2&*5-
@r4724
ACGGTGAGCTGAGTTTTGCCCAGAAACTGGCGCGTGAGATGGGGCGACCNGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCCCTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTG
+
@4<8$(F>375+49.32<//G8/3"0;C)=0"#(E;:2>G50AE)5&!3!C<(GA.H>/(6%)0B8#H#4D1?H.8EH@50@(4;"G;,GEF=<CAHCC%9H>#+.,F/;$D$.G"7@8?"E26CH)BF5@:/$+.<854<A3!<)84(H.A*6G"3H/,8A%6@F8A.)9=!G&!=##$F?4-9BCHC#&%D?5;&="H-(2%%;)983?F39)1%#"/,"0/F')490C"*%9;?:1B5D!!::!H!%/*:(<8'0E#,!7/G156+#62
@r4725
TATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTC
+
8/!6B:/3+E5B.D!<*FED/>?:E0@G4G1D!8%:;55;A69%6'D(>+A<9*3&!8G1(C+$!-0(6
@r4726
GGATGCGGTGAACTTCGTNAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCNCTGGCGCATTGAGCAGTGCAGCGAANTGAGCGCGGTGAGTGCCTCCTTTGTACTGT
+
)A034&(E="12,)&$*/@9BA"F%B.&!BC:FB>@7G@C">+:5:&&3:!&)F?F>#+@C820A)#BF.99B2)!29926?E;9B3A245"F;?=+!6&$8;*2<A+&=:4GHCD=.$
@r4727
GCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGT
+
3::"/+=<2C'&B%A+?),5>5&1,5F>2B&GE3*A&'&,8:<$G)<#%)49;<C(C)++E4
@r4728
GACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTCTGAAGGCGATGTATGCCGCCACCATTGAGAG
+
0!F3+>+>FG/@:"$=0H0'=;457<4<8C((@'4:%<3(2#B>C<E*B825A7BCB>DFA,ADG5(".;-+&$-6<-D273?4/:G*8'&&0;"5G<&'A@(<.%(?D'C*E-D&HC$E*752((G)
@r4729
TTANGCNATNATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGNAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACACTTTCTGCGCCGCCACAAATNTTGG
+
'((%$$$!*)'%*+%!+%+"('+)+"&#"&!#&*+(+#$)&'+#'"!#'+#&*$&)$"%+#'$%"+&!*)($"%!$*!#$#$(!#*&#("%!+%"(%$#*!)#"&(!*+$#)&%%)#"$&&)+"$($#+)$*$%)(*'%
@r4730
TTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCC
+
C&*>BH)DD*D?5'C3@*@G%!*'>1F#&%68C?>(4*8'/9@G*-3C
@r4731
CTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCT
+
C%;!<2/DFHG'3GEC9>-<C;,@>7E+(3:D<-H7*C";)
@r4732
GNTGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATACTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACA
+
&!(')*$+&*!+$$%!$&$*$')''()(*(&!&"#'%%+$&&((*%'(!*&*%!+"))"")(%+(#'&'$'"(*'$%"'(!*&'"!&$%*
@r4733
NTGCGGGCGGTGTTGTCNTTTATGGAGCGTGAGGAATGGGTAAAGGA
+
!'+((+$+"*+"+('*'%&*#'"+)!%*))(#$*'&*'#"(!*'$'#
@r4734
ACTTCTGATATTCCCCTCCGGNCGATAACCAGGTAAAATTTTCCGGTAACGGANCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGGCNCGTCAT
+
)D=B9;E5<:;?)A/C68.47!(*&<A%(+<<&C1:8&09$+:/<'*!>6:F!GA-:49+7%.*=(5"*;'($,%/&1:"!<F>4?1#6-%3CF&:
@r4735
AAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAGATATAGTTCAACCNCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTANCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTCCGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATNTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTANAGTCATAGATGGTCG
+
"+"%'$*!"''+*#!)%()$#&%+(!&&)#"$)()"!$!#%+%(#(''*%+'!*)'$"+"+%"#)%"*(!&$!'("(%'!!))"))'"#"!!*$)*+!!$&$*##%(*+#+")%%$&+)"('!**&*$&''""*&(!*#+%+'#$('*"++)&&$*!(()(#+'#'%%($#'((%&)%&!)'"!)(("$&&()*&%$#&!!*$$''"))+*""$$*)+$+&&&%!*$'%)((+)*#%*$&**##(#""!''$$)'#((+$(#(#&!+&)'$%'++$&*!"$)%)))%!*%##"#**&#+*!)&'(!%#+%(&"*'#((%#"#!)&!***(&&%++''"&$"('(%''**&'&*!#")#*++(&$&)''"#$+#)(#')+!)$#&%%&&)+!**)($#$%"!!"!%+(!))*(%(("'##$')$(%(
@r4736
CTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACNTCCGGCTGCGCCGCGCTGGCATTCTCGCCNTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGT
+
4C"#<86(,G+'#-:.+#@%C1;"&=!+/CA9/F#&1&DG-A>+E$0%2&G$/)%/55/1B-/8D*;)%6D=H@4/;,68(G@0459!20=C))%:/2>0.E'0.-E+E=)5@8.2*18AE8("F&2'3#+%,'080<1<B4.$C56D,%&H(=>G9&!3D+%+D01F2A10)&5!:':<.">!=C4.F3@9;5C=H<@#!7E(+>(F-;DC1:5B-;3,*1>@1C;&04"")DD@#'G">%06<*>1>6D?!!>G;'-A%30-@H):0:/;E);@%-B?/CA2*<+FD8*G(D+20%5+0+4/
@r4737
NGCGGNGCCGTGCGGCTTCNTGGTAAGCACGCCGGAGGGGGAAAGATATTTNCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTG
+
%'*)*$%&+'!$"&&#%''&$**$#!$'*#)*%$)*"($!'(+#"!*+)*$#+$%''#!)!)%(&*#$&#!*%'%&("!&*#!)!*!%$"*(')'&%"#)%$%*())#""
@r4738
TTCTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTC
+
&*#3F-!,G;D;;G+-A8=C4@5GF=":,)/-E"EG'>AE47C?B#$7&C,8+DHEGG!B>HD6?H=,()E+6G:&5%2+=.%(3::43CD9*D?>@DHFB3:C):)473#!?23@;,6F99@@*+,CH<$*4!)%2#E$-?$27B<DC+@)',-<7CH@66:;H2*=4&9DGH4,14:'9EH;4"'F"G!>%8$'B499!!-$02(&H3%3DH?972A=B+5=@#&)0/7+3':.)#)95.8G/H*5.4<'(C12-'%D7FE>/,(.&A;/46(9$.7A,<1+@$B8>#*G/)>D9?1*E412(184:-.;4><
@r4739
NAANGATGCGGTAAACACACACTTACAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACT
+
!$)!%"'+(#&)"&"*"'*#*%!'$%%!&#')$+&"%)"$"+#&$%#!%%(''&''&%*!'&))&$%#(&')%'+#!'!#)&'&(!%&)*'!$()$&*+)&&*)"+(((%*&'*$(!#)%**+"(("%*$%*(#!)%&$$+!
@r4740
GNATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCNATCTATGG
+
+4G.(>5$217<+.").*+?"%D&&"51<42"=DB19#(#1;.7C=(=7(D/#)3382&.=;6B6<7C&0;</06"$(&1'E1$;:E9+@*H?:!'#F8E*?A"$%5B%;9.!76,-*>/A:
@r4741
TGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGA
+
BC'D?.F>7&8"6"7-?!9&09AF0-6>&.,%!89=(7F1%A(H'<+B7#($55=!>*B&1/2*0:CE"(G5<2<#0!/C39H08,CC;*"&.(*AH2'+GC0$A$4EB:<<?1/%4E!.?+5,25D;$7CE3'63:>*,6F>C=!5%F%(#"8'<3CB$7@:5*:7C46*'!?3D6D7A.=39!*@>8%1=,*F8"39&G28.4&>+F9G)+EE1>6<1'4:0
@r4742
AAATGCACTAAACGAAACTGAAACAAGCGATCGAANATATCCCTTTNGGATACTTGACTCGATAAGTCTATTANTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATATCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGC
+
6";H!*..4293"D94:=6D1+(64;?'0706/8C02H;2#!#+&??89D/"7CBG8C3B@>-HAC72-F9@A2D09%@1%52:C:)F%+-;",H>EABH#.;E)!%!'0?''2)17C.+G*&*45.9"9.623H,@&1=@@)$'-+-+B@G(5AEF=CH
@r4743
TACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTNCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGT
+
)5C8:)!>HDF*@!;!&-B(*'*8!%8<:(!G$$FD'!#,&33AF,+)H;:+)7&@,?'33#0)(?30@,;"#'5>CC>&:+1*A#8+(A/)A?56&&8F71A.',B3@5A&@DC'D'.*,3;@>-,0E+7@:A;3-#20"&A1'EB
@r4744
CNAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATA
+
($+'$$(!"%(#"(#(($*"*+))%!&#*&)%"&%$#*'%#%!''!#')+!&!!'')*&!"+%"+$)!#%$'!&(%&*+!)$#"(&
@r4745
AGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACNTCCG
+
6F*AC/B42%6+3#3,>H=,:"F;%,6$52G*G@D/!+?0
@r4746
TCCATTTTTCAATNACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAA
+
E@%HA>E?:'6A=D;:@D+*?3E5?>(51,?/=*HCD!D/*(@B,>G/0(4G1/.#12C;33E8AE>B5D3/56+
@r4747
AGNAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGANTAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTG
+
*&*(%*$+$#($%+$$%*!+%&"%#*!"$$(#)#!&")''*)*%($+!%(***%+$)$"%(%%!)&"!&$"""())%"($$##)*")(*$!%$!'!!#&&&$%!)*#"'(
@r4748
AGGAAANGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTT
+
5&+1;:C(&>H)A8#1&G";D*$<6<*:617D?*%#?:1%!1GHB14-+E%1:7F8#7/<)
@r4749
NNACNTAAAAAGCCNANCNNGANNNACANGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGC
+
%(&*!&(!(''&$'(&!*$$%$#!&&!'&)*)')+$+*)"&")+$'+)"(%$*'$$*)('('+!"!&%)&($
@r4750
GGNNNCGAGNNCGTGGCTCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCNGG
+
)*&!&*!"($%!&+!+$$%!#%%&#%"')"+(#!&*"#+&+$+)"!%('&%%%$%)'$()+&%++&$&%)*%*#'(%%!#$
@r4751
TGCCGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCAC
+
0:F2,;'G:<2/14D-.(>D$007D@"!?1&.3D3,&H,;')46@1B817!1=',>()@
@r4752
CCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCG
+
9H)8'"2$2,>?<@B*D=<D4#A"/&,G02@96$C9<"G.:&)G:.<';@@G,<*-A?%@,)0AA.+1G$9$>->4C>
@r4753
TTAGCGCGTACACGTNTTGCATTATGCCAACGCCCCGGTGCTGACACGGACGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCNGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTNTATGTTCATGGATATTTGTAACCCATCGGAA
+
8:"=<)@H"H00?355.4,@9>$A:68&5!-/7:8D"1/5!/6E!*2"&858+H++1*<;#9&$@1'EE23,B%?3)/44;8AC95!!:H%5A!0#,D3;7''?((06GBB;,7:.H3>#%7#&,,+?>3F4'7,B7(/B4>E;70C.179/$(/;9'",F!')8$25G&5G7,@71E9+
@r4754
TGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTC
+
:>-+0/!=AD%&..:G(%$*:.B@@%E:9%"460&G"9*@?H*.&+
@r4755
ATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCACTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTA
+
4?10",88;'GGE52'A46*4/#D+$)H*,41'8G$>4D),,D7-.E"$%870F-C'77=)1H&1-F5-44G+:2=48GB7-,E");/*;5C4<*%:5@+/!$4:0B6=(=0
@r4756
GCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCG
+
>"F$:*@-=F?!+&C=:?1@.:.)%0)*73,ED!$??3"997(!5%H5%&/+@,B;'(>=<,F8D5/,5$'/G&<6F>7;02-GG%8
@r4757
CCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCAC
+
3(*0-%2=+C7<&E(,&C5D7>ECH1/5:&GG3.34.D""$(61:#$14!D,6";:7?(')8#D#:$5;"<+B&;4D$D4=))DH@58/2;@&*=*+(7-G5?-0);+80"!*'+F71!.E,H9G$!BC(#0>&C0C/.#C#D?G+FB'@<@859:!-+!H%=">$D(E5=?),GA,-,0CB
@r4758
CNANAAGTACNGNTGTAATGTCCGCTCCGGCNCATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTNTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGNACTNT
+
*%"!&)$#*%*(!(+(!+)*+*)%%!+##!*')!)!$#%'%($++"+%#)$*'++*++!$*'%%*%$*"**('*)#"*)#**%"($#%()!#(**$&(%#***!#+(#(%+*(&'&%)###"!"+$!"(&*!'&"!#$!"")$%()""#%+'$%%
@r4759
NGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGAGCACA
+
!F#)4EB'#+C"!A&6A@B:97?1#E'!"6B(,)6.++6'(%,?)@<H3G+<)%7'9*:C%.A8G=51=3
@r4760
NNAAGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCA
+
""!+#'+(!#)$$)+*'&+("%$$#$)"%$)%)&+!&)(&(*&**$!&""+$$)!($!
@r4761
AGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCT
+
!>35*60+*G0D15'%H8"%>=$:878$?+"CF**;>:HG>*/!#BA<*.G6>>A"H";4B
@r4762
TGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTNCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAG
+
'%CC?B600<,>4.?#;&*A+E%%H3:4'G+?H)8,<6@>2GH49DD:*$<71"B2*'ACC5*##-H@29CH4!)2)$6H/=64;B5B#B7&*9E@-C"1@1H2(3+B'@/).69A$0D;19-@5@!-/)@3:=!%/99<H3
@r4763
CGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCC
+
)3./E<;)/=!4.CB9:FC82<A,6+D,>HCH,%5*B!G6!0<(7G%C>#'26-$<6(<25=3(.B=G>'<!B(E'1H>617.:,+8%F;/8+A)!0;H1:E"8.,;"+8<)E:.42D,
@r4764
TCAAATCTGGCGGCATCCAGACTCAAATCAACAACCNGGTCGCCTACCGGTNCAGCCATACCGGACTCCTCCTGCGNTC
+
"+3')H:@3"-@C=%5#=E,,*H5&?C0/F$);5CD?25'!>#E.4EH%HA!)6?5%B.8))BH5C+2@$>F5E*66>6
@r4765
CTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAG
+
2/&4+F!>/$>$"*739=.5&;3EA/H#=-68?#(B*.H>@+'.FF;>/8*"C/.,G%<10&/DC<G3(('#6<G'-.'6>-("++&'%3&481?942;6
@r4766
NCNACTCGANTTNCGNCNTNANGCNNCNTGCNNTNNAGNNCNNGNTGGNNNTGANNGNNTTANTTATGTGGGNTTNGNGCGGTTGNANNAACGNACCCTTNNNCNTCGNGNNCCTGCTCNNNNGNNGTNNTNGNCNNNNACAGNNTTNNNGGNAAGGCNCNNTTNCNNNNTCNNNTCNGANNTANTCCCTANANAAGTGNNGNGTNNNNNCAGTNGCGTTNCANNNNTNNTGNNNGNNTTNGNNNGTGGNGNATNTANNNCNGNNACTGGNCCGNNNNNTGNCGATTNNTGTNTCGNTNTTGNANGNTNATTNNNNCATNTNTCNNTCNTCNNTNGANTGNANNGTCNGNTCNNTTNNNAGNGNANCANNCNNTNTGNNCCGNGAANNCNNGCNATAANCAGN
+
""!$"!#$$!$$#""!!!#$$"""$#"!"$$$!$$!$#$"$!#$"!!###"##$""$!##$!##$#$"$!##$!#!$#$!#!!""$$!"!###"""$#$$$!!$"##$$"$#"$!$"#""##"##"$##"!!"$"!"$!"$!"$""!!!#$##"$$"$##"$!#$$$#"$#!""!$!""!!"#!!"!#""!$##!!$#$"#""!$$#""$!$#"!$$"!$!!$"$""$$!!$##!$!""#!$!!$"#$!!$#!#$"#"!!#"#!$!"#$""$##!"$"!!$#$$"$$!!$$#"$!"!"!"$!$$""#!"$$$!!$""##!"!"!!!$$"$#"!"$$!"$$"!##$"#!"$!"$!!!$####!!##$$##"!"$$$$$"#"!$""$"!###!#!$!!"#!"$!#
@r4767
ATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTG
+
+&F%.,6C$7/-/)+;D)2'25-0":H0>+%E.!G</,4;6'<.E--?2,@)9+&(62"C.E5*&<AB+'>.@AHA57*7H;(5'*8HG"@@C?DA+%*%6G6A'"1':-0*B093>@E9=C&&0"$%C"=;8!G0D''E%H,(@0+@#08248,B
@r4768
TCTTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCACANCACTGGCGGCCCGTTTTGCCCGTTGCTG
+
###'%$+#""$*)$$'$$%+&(%"%#"$+"!)#+'&##)(($&)(*'$+&"#*(%$*'"(#)#!)!%("+(+%'*!#*&'!(()#(((!+'$(()
@r4769
NCATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAANTACACNGCTCACCTGTGGGA
+
!+)!$"&+!#*"!+'&#%$%&#(+%"%))$&&%%*))!(+*&(!+$+#)%$"#*&+#)'+$"$'#"!&$')'#)&!+$%#%)"*$$#%!*"#*#"*'+'(#(%+!#$*$(+!'+)
@r4770
CTGNNTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTNTAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGNGTT
+
*%)##(+$$+*)'#%!!!'*!&%+$'*%)+*$%%('&#+*&&*$%$*$)"+'*#*#"+#&))'"*)%+('"""&+('+)"%#)!"%#&'+")(#"#)&"#&**$&%*)$()'()%+%)%'(!&*!'%&*!+(!'"$#"(+%"#%###'$**$#()$+*$!+
@r4771
CCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAG
+
559>C=%G;(?C'E==!87*;$6D3539#>&)C-=AE>,;3$)$D)+,"0=7>#$>D#',A.>*-.(8C*4E'7;8D/A
@r4772
TTTCGGGCTGACGTACACCGTGCTCAGCNTGTTTTTCAGCGATGCGGATATGCATCNGCTGGATTNCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGATGTGTC
+
,@'4E,6&,F6@'H,'8?=@.*8<$,H%6007(F7B3$.8&0>7@G/H&(@*?2F>B@<,:BD&6#%=E@(E&;0=38(5'-?0"/2+-@29'BD5F""7C78(/-88@1?9<H,H-(!GF:A7&E-3C2"8$"E<F,B1;>B<:>".-+C
@r4773
TGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTNTCTGTACAAAACATANAGATGATTAAACCCAATATTACATAACAATCCTCGCACTC
+
)+3-"=<2(F-B/(3!'1+2E"H4$@3D3<2!*,&GG+C5$08@"8>A6*G-)5%%F,*-01$/6E/F@-)4#%4H>''?!#HD0>,?4./@EC,!5#)(!
@r4774
TTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGAT
+
+@);D)+HD>A%-/7=8@32)4-+)!0;3.4*B61G,<.%@A'7+=8&:CD'7:,A1(*<<)'A(;
@r4775
TTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGANAAAAAATCGC
+
8$."1%=<134.%1G&F"C(H8')7(/=?</55F5@&EG0',G=$)B0."E:D@-B,?H6?44-5=0#8:"(D!F2C&!*FD5,>?$;1?H7-6,4=6$884&1.@6%(7;2?4H%E"&HB$9;57.'/1&B-,&$@.=>27D>"*C18>4-7#-.9;(DF*@%3:1G<52G>C.=5G!"4/ED;3%$:8F5#4!)<";9,02/3&#(A0?>F)'C35,G=2#F,&A011#D
@r4776
TAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGATCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGG
+
.&9;G#:*6DA?=?=<+$6)/2*&ECF),4'0."8&@/,?15*F5E%0F.8H<5-)0,04!!%*D;C-;2"+(3$"&);'",6,&5%9'.%+9(08/.66-EB#F68E2!@'2E14"',@$A&+E!7-/<&A0C4@GD7=%'BH3$!.+(A';9@/0FF<$:7##8(F*$!@!A#4BH<%+A*->9%@5C3#4)&
@r4777
TGACGATTCATCCCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGNATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTA
+
'9>!9;C:CC'?AHG19B#$40F:D1$15."<2G'?B4:2$7:":7%4$=D!E#0$(*G8*5A+39:?>3;,H**<&C050A@#4!";*,'/#8G*'2;8'0$1*(6*;1&3*:3D?0G$5#%;4+D.F$@E:)+8(1&/AD3*FHC%!%*3(6)%5>9!//D@?,G)0F
@r4778
ATAGNATNNCNCNNGTNCTCCACCTGGGTGCAGATTGTCA
+
$!#(#"'"!#$'##$$%#++("++"!%(&)#)'&%"$())
@r4779
CGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTG
+
=:<;68))#%@?HG#;$2)@2:,'A<*03)/F)G8?G==!#)DH937,E3'!!F*5D=&>&'*.7'CG6(&
@r4780
CTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCAGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGNAATTGGTTAGCAAGTTACTACCG
+
6+#9),6'6.%H=;E<'3-1#7"1'G&305@)++.@H6)=)!2'(*@*'/5$17A"-"E+!"4-B0)1320=@./).;2E9%B+8"("-6(2/G/;8<</0&&$3%2=&C@F"@1#0+640FG=
@r4781
ACGAAGGGGACGGTGGTCAGGTTGTGGTNATTGGTCGCTGATGCAA
+
-E/A'!(E2%44%(.+.-F:$$->>F*5+//':8A%$%$7)($&%9
@r4782
CNCCCGCCGTTGAATGGGCGGATGCTAATTTCTATCTCCCGAAAGAATCCGCA
+
#*!*%+%!)#)%*(($&(%(""!*"*$*+"#'!"&#&($&%&!($+)!%"!*#
@r4783
CATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAANCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGAT
+
8EH"%0@0=D96;H.9G3"))F2E'$A:.H=+G92#EF)*"@+>#597&(8!@?1A8!@';3F/@9CB@F'-F;G2B*!$E>)$99->8>E53GG)'$0E98/%/G7A7&'2=D>E=*,.H4F4G-8F
@r4784
ATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAG
+
42)*%.E$F%5$(B-6)@.H#$7!A<->@)"!0=B>*+H(F*-&'=H*:!=&&4DF/HCGB$H9>2.5):%=D@;",'<1=4-1#=*,#-B%?GE#"9:*1$>E>F'74(>A%>E>3D2F/H:9848.:<H+44;*3$'F0''BE#C($*32/6<$.!9<%-:B$
@r4785
ANTTTTGATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTC
+
&((%)&#*+(+)"'#%$$"(&)*!(((+"'"&*&&+%&%'(%")#"+)&+%*+()&#&()$%)$(+(
@r4786
AGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGTATCTTGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCNCTGCCTTCGCGA
+
.4FE;?:&H4954E"DA3G@,"'>8E9G+%,*=@/:)G?B4*C6F>:$(!E&;2D=%((/:-;-):;:320@-90<715%=H:#8->D#GGE$%<2B"#0++#*2':F:-
@r4787
NCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTNNGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCATTCAGGGTTA
+
#"83-"F#=A89289(6C#-*?3F!(-85HC!2*5>4:HH7.79HH47,87C.&4/0B67';HA,>$08H%"?C?!3"==,DB%:44D6,B9;H(*:CD#DBD3-!"+,'F4$>.DC;&D1+B,
@r4788
NNCNGGCGTNNNGNNCNCTNCGNTANATCTACAGNNNTCNNNCNNNGTNNNCTNGNGNCCNAACNGCTTNTNNTNGTTNCNNANANTGANNNNCNAT
+
"""$#$!#$!"#$$!#$""!"$"$$###$$!"#$!!##!!#"$!#!$"#!!"#!""#!$###$##$#!!!$###!$##!$!!##!"#"$#!!!"!!"
@r4789
NCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGAGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGTAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGG
+
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
@r4790
TTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATG
+
H"76BBD56,1-+)-E/B5<:>@F<;%&A!(7%G%@=D7,D"F";>5>$7>
@r4791
TATCCTGCATTCCCGAANCCATCGACGAACTGTTTNAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTC
+
+'!%**"!%'))&)')!%$%+'$)&')&&!+%)%)*!+**&++%$!"*%&%(+$"'"%#)+'"%"'%$#(!&
@r4792
AAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCAGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAATACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCAGGGTAAC
+
&,#(5"-8>33D$G=A9D&"A'."F>B>1#;$DB4??:<>:9*,E&7@*#6@2E9>-E@.4*<'2?6FG7>A%&'/@&B27A45'-0D0&()2+"3&+?8H6&"(151F/C?("=&BF6CA<5:>A?GB!-B?4G:'C1%'>&<H5A)?4'DC7'40B'C,99#"3B-B8EHE%1!,?#H91/F:8/+-;)9,HE,D>>"H%2'0+H<
@r4793
GGGCTCACAGTTCAGAAAGCGTGACGGTCACACCNTTATGNTCAAATGATTCGGTT
+
;$3='>;%.@<*59>.'1G:-())<1,*G4+&FC,E&/*&+"$F.C8*>.A;B$3C
@r4794
GAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAG
+
9);@>8)8?$DA3;*B3+12+2':.A%<-?>-B)'-4)A4A0E12&3*:5BD=9)!)>%0$184%H+/%B,7>5E1;F<G=--B.4B1&%*2:<,-<!<D+&HFAH2-7!89!=-D(0A%"!G+66A!-,."&*+H;*'B'CG1"6AFA&$1=4"@79#E<%1*=!@-#1@GD+<%1D.50%!#-;,#A='2=*#
@r4795
CTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTG
+
B*2>'2$89*F90%7+"H=8*>E"7//($;,=/C*'$2C,&26.-D6E4%85-%&9C>B-*B;4.")??3H$D+A))64,,39&:-;:;6@C$@.%%&$+D:/6<=(8;"@6EGE"=%G="A<B;CE5:A$G8H'8"7-B@DD!B>:G;E4**-!?,!00F%8:>3'B54,@#=&!B*=2<'AE&!?4A71GE$=B!$1$D>FF)B05?&@G6#+@
@r4796
GAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATG
+
=G98'3@#0/1F8,F$@=>/!9?7+AE62F"'C78;#;H5?A!EE26+A,A.2F645698#<B
@r4797
ATTCCGATTGCAGTTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGT
+
1@12",%A4*99+=H;?B0FF&./#B"H8)AG0/:>?+@60-5(-)58>-AG6;3-)>21='42"91?B,7)4:=5"6,8%E)23$-:.>!<#()E
@r4798
GTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCT
+
E-;0>(3)0>2*0=&=2>+#?&#@<3G+5E<*143+1$ADC;
@r4799
GCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCT
+
&'+%$%!")!!'+*'##%')&)"')%'%'$#('+$"")(!)"!#%&
@r4800
GANCTGGATGCGTGGATGGAGTCCCGGATTNATCCGGTGATGANCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGC
+
()#+()("%!&$"($'&#!""'&"*"#*))&"!&+%+*+(!$&'$("#)#()+(()%)!'*#'*&%!*#%(&%#++#)&%!&"$+&*!!)+%!
@r4801
TAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTT
+
%4?.?F-2)4@2D8"<G1>.%C!.<E>63E>/45=:?&G3=43@!6-:D-(E1*CE(H7098C@.F?=*C8./6@D*-4B15C:$;*
@r4802
CCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACNGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCG
+
)8$A60$07./18=8D7>H"(>'!!9E68CD5-91EBB@47C8H?4=;.E+DF1+8($-@3"8%!-C'')2;?"1@(<>3.9$!72(H<(AA#?$F:C,F'2-0D?D7$71E*=.353!))!9"368D(4.3'1@.HGG=7@HG6A25.)&#?F8
@r4803
NATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGNCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGC
+
!+)&+)*#'%%#)'($&!&#&%"!+!!%#'"#*#!*##'"!"&**%%(%!'%$#)$+%#(+%)'*(+!)*$$**)%+$&*"$((#+'"'"%%%%((#$
@r4804
ATCANCAGTNCTTTCANATGACNCATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCNTCGGTCCCGGTGACAGTACGGGTACCTGATGGCCAGTCCACACTGCTTTNACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTAAAATGTCCCCGACGATTNTC
+
'"%*"*"'%$)$%)'%!)'(#&#(+$(#)'#!")$%(($'%'!)+!#!&"*$+$#(()&#$&(+$%!"%&!"%&(+&*&""+*+'"*!&)("##)&#+)(&"#&$'%+%&)'+""$$%)()%*$+"")!+(#''!%''$)+*"#(!"$+"+$+"(!+'()+"&%%)"$"!*()('$")&%$%'(+!!(&&)*(++))#"#")()'"*!#%'%(*#$'$%
@r4805
NGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCAC
+
!#5//0*33#58<!7H5E:",9HFC3AC%H4/1D?$9"7546@6!=H,.=;F3
@r4806
GAACCCGTGGAGGACGGGCAGACTCGCGNTGCAAATGTGTTTTACAGCGTGACGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATNGNGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGCCCGGCTGGATTGGTGAAATTGCCGCGTATT
+
%"E6>?D9C$1+'@853;$!C1EC0:;H&):3GDA-%H1A%$F$D84?7D0:<E#&'E6!7#,"(:(-(<$B?B7-6/4A$,E4?/488%D<,)H%!&!%>$=!&.65*$F"$:C3+/1'-"!C.?>9A!>+8!EF);'6D!+-A,A<C,@@B?'5($024-/0=;GE%=A;C(C$'?!2("G'.#3593F2CD)#98@!%6$"0+498*2&*/978!+:B-D#9'+'-14!<*(040"@7
@r4807
CTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCACGTTGCGCCAA
+
4;<*='6EHE+@E%91,)2'.$)"<:7"=#0<B05E(E+'H1@<;'-!.D+@D=7A#*5*%*D;*4?/<+.@4#*!A(H3<G.%5B?E<@=!?9";>
@r4808
CCAGCCGTANGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCNGTTGCTGCTGACCAGNCCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGG
+
@/,B,@C?:4/.2=FH'E&$02E"#=@$"=H@CB1+&!-*@D'%<"+11;!;&57=)GH%9===#26DG,(5C*%,.B71>GHECD)68!:D.@>;7,;=(E=$41!!&@1%6A/4#9=';8;5""
@r4809
CGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATNTGGGAACAGAGCGGCAA
+
/=0D='&94$A-09<CFH"'"D0@/,#(>*DG,2%<2)F51+6HGC%(H0227&1;>)B2FC+FA(-17E8A2@1.G%61,E@76DF$.$)=,)8G.DD+0!F/.+7(%F)*F%<G4%0#:;:$#C"81C#
@r4810
NNGCAGNNGCGACTNGCNTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATANNG
+
!%)'#)'#'(%$+)%)%)!%+*)*%#(!*&)+$%")%!&%$$*)(%#*'&"%""$!+))#+#)++"*#+#*++*"(!(%*#"+&!#"&&+$(!'%!'&!++&#$(&(###)*&)(%&'!"!*+$+$
@r4811
TCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCTATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCNGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGC
+
=.;"B;"B($@B(1-G&@@1!A,D<9;&+("&//(,$D5.=0D$G@87A>*460H'%5)$$$.28;!B)2$"D@F:-D&"/ED&,E"E(8,A:DDE724A+!:!FD8*C$<2DG8!7&(>5."<B6&/;(D@B"%@099,19.2$%3&(#*;B=5C!.5F/G(>H52(E45?E=7)8+5B>564495'3<??6;:12++&G'6H,08,B);;(&<BG)$:E@(B1*+9(#!'"$(-/E"*C*-%,9>.--C7=,%E$F"B2!&6:-G1<HF'C!C405<A57!(AE%47@$$DA/-C5$<4@=*9C&8)&43<7B@-'7$+A4G04%#A#E%.4AD8H'+?!/G2F,:!AA8+5'7%<*.02;-)C-%H2G&/39?@(E%06?7D+0(?=9D&5A"#&G31F(
@r4812
CNCCANCCAGATCNCCTACCGGTTCAGCCATACCGGACTCCTCCTGCG
+
('#$''+)%")%"&!!"*!!(&#)&#%&!"#**!$%*&('(('&!!+'
@r4813
ACNGTATATNATTTNTNGNGCAAAAGCNANCATTGGNTNCTGGGGTNTTNATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCAT
+
!!"*)%()#)&&%*"'$"'&()%**##'*%'$$*)"%&!*"#$)"*!"'"+"#")+)#'!$"+*!"'%&)((&$!(()')$"'"'((+%!!)&
@r4814
GATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTNTTCAAT
+
59+=:EE")D#*)GB='36/2=<5$+H8C4?EG'#)0-%$GB=B!'F&+H!AB*(5,1H'A!'8")D1$8-2
@r4815
NCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCGTCCGCCCATTCAACGGCGGTCTGNGGCNCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATG
+
%"'+((#&*""%%)*"+$(&!"&'"*)$!#&&'&+&!&#*$)&&))!#!('()'%#"&*("+#$(+(!(*"!)!!)&'!!*!#!+)''&(%+%&$"((*#(!&"')+!%)%##%"+$&&+%'''"&(&!"'!""('!()&'$+%%'!&$%!+#+*!*'()&%&*"''+'&#"&#!+($!(%#$(%($'+"$+'!!*!%"+#*&)')&(!#*$!'"("*(#!%
@r4816
TGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAG
+
/#&/0C$=)%?6&/H3B8A&0F#EBAF#D0&6<:''8HE8A/A/A.C2-GF*8(;,>72')7B>"@)1%A=(35FB+A/$>C3<B&%:H&@1%$05
@r4817
CCGGAACCGGTGGGCTTNTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGATAGGCGGCACAGGAAA
+
+(!(,#A%#9#)38==6H#200#!584?7A@H:1%8%>4%<H'9G5<<<0CC-#'H-.%4'</,?>0>D%>)F@(/
@r4818
TCCCAAAAGAATCTGACGTAAAAACCTTCANCTNCACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCG
+
F(?832D311,)A*,=+7+$A@5@5=-?:0F"+CE?&0HG!+6<%(D1A#D$)9.4%8G41-?.'--69C9+A
@r4819
AATGACAGGTAAACGGGTGGCNACAGTACAGAAAGACGGACGAAGGG
+
10*H%-/B.3,)F+&,>8B.1.,?678A/:6E(((C-!76>-((.>@
@r4820
GACCTGCTGGGCAAAAATTTCCTNATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTNTTTCAGACCATCGATGCCCACACGACCGGAGCCT
+
/+$$%7#5817G9#)?2*(+CG#8@!#'7;>*GD%5628(F=H<6)$"'!&6<;-H(F-G!==?1A>6;H*=H1F+D2+%GB%3'7)#=!5G532'-/?!/D0<,5;,>::?4<AHG,"5DDB-B,#!,?C9+76G,%5
@r4821
NACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATNAAGCAGTGG
+
((+E'8;4$8H0)G9"3"C?56BF*,8+B$#+3B'2;?@..*%#--,;0G.6;02.4="97AGG<G94;//3
@r4822
TGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCNGTATACGTTTGCCATCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGCTGTCTT
+
+,!<C$,:4C:1@B+8.+/9!%&0G=F'E.0G&>5&/D8A-<F:50%>DGD&.9D.6-BE"+#66-#$.D!A,;0E-*(*3+#CF'(EH3%2-2:/"!:&E:9!CE)%5'!47@6(7;FG15:H@8-3C5.5-8G7B2@04!9G78/7B.1,4=7664&#"C-.<A(-4"-5(D19)CC:0!*:D<?G%)73G-82@&D1G6,>G8#-AD=;9F).F0-B/D))C16FB<#5?;
@r4823
CGTGATGTTGCTGCGCTCGATGCCAAATACACGAAGGAGTTAGCTGATG
+
-:+&*E9C$1;F8.3F*/);+D+&7<<#6**&D>G#/A@2E);C&,6*7
@r4824
NNTNNTNNNGNNNNNNAACTNTNNCNGNATGAGNTNNGTGACNNAANNCAGATNAAGCNGCNTNTNNGNTNCNCNNNGGTNTCANTNNNACGGACCAGNACNN
+
!"$!"#!#"""!"!!!$"!$"#!$#"##!"!#""#"!$##!"$###!$!!!"##"#"#"$$"#!$!!"""#$"#"!!"##!$$!$$!"#!"#"$$"!$$!##!
@r4825
CAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGNCCTGAAACTNGNGCNTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGT
+
+G7%F,B/..2=&,.+6@75$&:.0=6A!B%/E,4>'5,/$H>'68.*$.5DG+5/A9."B3/*,+E=81/E%(05:>"1##2"<78D*C5%5#9(1+?2'3"E"';$9
@r4826
GAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCNTGAACCCGCCTATG
+
9A6$E#$A1G321,622>-",;D/!.'A4,6#>6$"<,$941B;=H>+66/&:)89!=*.,"=C*=&G=#00@&B/0EG53:?4/?BG3//+%%=:<)F;)G5!B(&<3G4@=
@r4827
GCCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGGGGATATGGGCCGCAGTGAGGAGAATAACATCACGCNGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACNCGG
+
B:7D$+)=64F85(6=2><)20E:==>,($'$0.#"2=':F"5/F+B1#9!&(3-:)2DF%)>0)@,7B*B0->,8#F5BB%)A$05.@"BF@F67D,.;E"9?8#&G-91*;@(#++31<@75+=%6"F4'E,.//'D/E:D?A)B.#-#D,?;
@r4828
CTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGNTGATGCAAATAACNAGAGCGGAGATAA
+
!5?B$;.6$>'<5"(H.E8"97,8*&2B(CF)CD*E7E)A%2<#6?$$B<"+@CF6<(!D7'CHAE-D#E0E'?H+:4>&
@r4829
CGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAA
+
D?+A85)()1@/0D5=5<.+FH#@7>%?9CAD71#AG>2(@B@!40A
@r4830
TGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCA
+
/26/:AH23A?AG0!;-D(%D/$B'?'21BAH@B+6-EF:9)#?HH"H8(6DB7F>!=DH$!%D@;+@3;B1,7((,'?2%!+=F(?*
@r4831
CCANGTTGTNACCTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACNGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGN
+
&'(&#&)%%$!("+'!#&!'$"#''")*(+)#"#)"'%'$+&!+)$(!)+*'$$%)%(!)%&*($++*!#""+(($%(#%#&*%)**#%!*+#%(&'+&+"*()(
@r4832
AAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGG
+
>!*(!C#7+=/A6?3;>>5>;7*;=4CD65;?.,#3?*7C-
@r4833
GCTGCACCGACAGGGGCAGCCCGTCGAGAATACTGGNAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGNCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAANTGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCGAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATNTTAAANAAAAACATTAAGTNATGACGAAGAAGAACGGAAACGCCTTAA
+
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
@r4834
GCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGNCGGCAACCAAATCAGGGTGTTGCGCTGCTTATG
+
E12"=??*(!,E5'6;:,3G.=7&!B''A:BA>C72G<.$G2(9=EAGH6FB=#*#=;4=,=8128;ED.BH0=9B
@r4835
GNNTNNAGCGTNTACNCCTNAGNNGNCAGNTGNNNCNTTNNCNCNANCNNAATNNNAAANNGGNAANNNNNNNNNGNGNNATNCTNNANTNNA
+
"!!$"$!#!#$"!$"!!##!"#"!#!#$##$$!!$$$$""#$##"#$#""$!!!###$#"##"#$""!"!#!##$"!##"$$!$$!"#""!$!
@r4836
ATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAAT
+
3G>.)4+=%%H>2FF?(2$$9"&),:FFAAC'18EA*@$@*%$+D>4B2%:$4@:6?>;B
@r4837
NGACACANAAAANTTNGCACTGGANGGCGGGNNTTTGTGCTTCTCTGGAGTGCGACAGGCTTGATGACACAAAATTAGC
+
!($%"'*"))'#!*'"'#(#$)"&#!)%)!"(+!%"'$"*#(#$$+&#%(*%)%$*!$%&)+&'(#)!$)"")#%+'*"
@r4838
GGAAGNGCGGACGACGGCAGTGAGCGGCTGGTCAGCANGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGNTGACAGTCCGGGCGNTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCG
+
'$'*%!+)(#)'+"!!%'#)((&&(#%+#"'!*#(*'!*%$%!'$+(+)&'*$$"!&('"%')#''("'!)#%&#)"*")#%$+!''!++(!"(""($)!'%$%!(+**"('")')'$&#&$$!'#+$*!$''**#')#&*#*#'(')*$))(
@r4839
TACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTAGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCT
+
+#*?-F1;4.15'15(4',+,?,*54;=?E="8$3,46#6C'/=F,?,,4.(,?.+(A07&+G"5/'<$H3?!B$<3)*'@2.BF4D,3(:C2""B?E1"/F31"3+1A,!$.3G$#@5=((DG&/!-2;F'8%-'HBF<3)D-:605"&A;G.'14>@:&888B7F@!6%6A$3)B-(,;8>>G=)3$A"11=A=+H+@(?@A:A*+8BD$EGG(H46<)
@r4840
CGCNNCNNTACCNNTCNGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAANGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCANCGCGAAAC
+
'%%!!)#!(#(*!*$*$)(&%#+!)"#*##$)"&%"+'$+##!#"%$"+"*"))&(%&+)*&$"'+$$%)('&!')$"&"&&#*!'$+"'%%++$$*$"&&"*"!%**+!+
@r4841
AACCCNNCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCA
+
'*')$##')*)+*'!!""%$%(#&$!"$*+$(!(!'!*')"#+!'
@r4842
ANGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCNCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTAACCTACCAA
+
#")%(+'+$'"%(*&(!"!'#**&)+&$%!*"(+(+)))%$%&+%+*)*'%&*'#('#)$)$)*$'#$&!+!'++!$$#%%++*(%&)'%'!'&)+*!&#+%(&!&()$("(&*)&*($'#')'*&"$(#""'&
@r4843
TCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGA
+
9H>%EF04!$>E75E.<',?=>1,4F0B75+2=>*?H.:BF<F8-9C;H,+A3;7?C@*!+"6E15DFG()3=<8,?:=9F;-00-F+:B!+:!/,"@9EB0.;0D52A*#<FB<1.1!9E?5??)%!=.&
@r4844
CCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCC
+
81;7A!?6;3!/@;*G4AH3B+570?F;==GC/;FA0"1+H:#E*3"&?<2<C+@-?&C%F9"&D&$;.@#"00G73)D<9=
@r4845
AGGAGNNATNNCGGNTNCCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACATGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCANGCGGATAAAATCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTG
+
)**%($&$!"")#)!(!+$($%)!#)!'$(+&)+!)%&")#""#+&+"()$'($(*)+'$"%+*#(&#'*%$(!)%!+!&*%$#()("('%%*('$(%(+#*)(*($$+"%+'*(&#!&#)%%&(+)'&''""*(""#()*!%&%*%"*&*''%%(#)*
@r4846
NCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCNATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGANTTACACCAAGCGATTCATCCCTAN
+
$#+**(&*!$"'&#+*#)*)!!(!!)")#'!&(#+&+')+&)+#$&%)*#!+)&#((#(*(%'&$##(&'++("&()()&**%*!*"&*!$#%$&"#&#+"'#")%!!+'$"+&$""!#("#&'$'+)###+&*"*#(%
@r4847
ACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCC
+
')F'<6";4C&>>52GH4>.GE.2$0:/$$0!*F@?-$48:F8:6?5EEBF<%5G1@&2@
@r4848
TGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTTTCAATGTTGTGCAGANCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTNATGTAGATGAAGGTATANATATAGGGTCGGCAGACAAATATTCCATGAAGGTTTATAAGCCTAATGNAGACAANTCCCCATTCTGCAATGTGCGAGAAATGACTNATACCGTG
+
'0F,@2H=FH:,:)@*&2,F;:GCC;!E+(H,?H>82D)92>D<=*<3D?>)B<5BG-E13FE!H"7>&*ACDE'=6EC%8<$7C!?(6.='ABGA+%*7C&@"=@-F>9)(6D%5'9:8>!=!F90%*61:;(:+@,G<4-5H3:!E>-><'3B/F+DG5-/2>BF,>G$9#E,$C>%=*DC+3-,D**:')25==-<<DD>EA&2@E$$/
@r4849
TCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCAAGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCG
+
,G"C5/2<!&B02B+$5)0-?639#+?*)CH/18)=.?94.5%(#*D!&#;>1A':!&;?,B94H>?>=<>;>,!,F9<F.8?6C80D("7$E!;+HE"7"D2,/2:A;;<;':!AG70A:)")8@G&#,B*68?E&0E&46$0:.
@r4850
ACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACA
+
3CB+=#$HB@B$/*-G&)>$6/*D)2*12/HGE<854&>,/&<FH.'#&(H/#=9-+3)#3*E/,3*)$0!1#H1#100',;#HE7G@1()1<-3A,(-D'#0<),
@r4851
CGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTT
+
BF:<!",)!@3A++""CH:#1-A7)/*;!BD6F<)?7?C+&9%
@r4852
TCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATC
+
)6H.6>%(!@6@30GB/?!-&>47-(./(10?*3=':E#);,27?0(17G(')?156%F@E>8+9!;#57E0/98!@+F8'3@EE?E&@-4CH+&7AG
@r4853
ACAACATCGTCATCAAACNCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCCTTGCAAATGNTCGATGCATAGCGA
+
!-A<;*6'C2;)&7850HD4<+G$FCA$/@9$?<//-472+74:*""&G>>?#/@G?E<:>&1)5%/$*HB+B@%"*(7#@
@r4854
GGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATANCCGACCCCAA
+
5?#C5HFC$,4)/D2-'H+(:/1,(;95C%=E?;66!/4B@9E,A%B)<++/F+
@r4855
ACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGNGTGTTGCTGAACCGTGTTG
+
G2.C&-:-E&C'.)=').D5,E>)GE;(FH1&"#@/,".)5<G*)EH""2<4
@r4856
GAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCT
+
5*FA$573<;EG)9(8"@D!+A564"15.02=)0@!"3B,3+!@-/;8'877&5&E/-+G33'34EA?"?>&9EA(.3"84)3<
@r4857
AGNNTNTATTTANCNCCNNCTNGNAGNNNNTNGNNNGNTCGCAACNNTNNNNNCNGNACACNCNTGTTNACANGCAAANNNGTCNAGTCCGAANNT
+
!#"$##"#!!"!!#"!#"$!$$!#""#!#!"$$#!!#!!##$"#$$#$"$$$!$$""#"!#""#$$$!##$"!!"#"$!""$$##!##!"#"$!#"
@r4858
TTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTG
+
3<6D&E!7;%7#CBF>;-H">/H4"8'+,3D16.!F36A2082$&,1,?:@/F$/D:H#<C=:;204;65@!'#H@)%;-A/))GC.:%?
@r4859
GTGCNGCACGNGNANCNNCAAGTTATTCCTGTCGNGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCAGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTNTTTTTTTCCT
+
&%*#"**$$$"%#&!*"!#+'&!!'$$#+(**(*%#!'$*&"'+'($))!&('%(*%"(+$"('+&#"++")"+'')'(''!'$&&!%()'*&'*+!)('*&%!$"!)&*%&$%%$'&+!)$*%#'"!$&#*+('!"&+*"(#&$%!+*#")((&$*#&"%)!(+$+&+%(#%+'%*)&"!&)'*%%%'%""(*#*"$+(&''%#((!+%+%&%$"#('*%)%#*'!#"$"$$!*!$')'%!(%)('
@r4860
TAGGTCACTTCGACGTATCCTCTGGAACTCCAACCATCGCA
+
=B<":23$1*H0&01(5980?+/;$#<6*<0E90!>3!6!7
@r4861
AATAAAAGCNGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCAGGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTGTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCT
+
""-AA4E3?3F+-E2"?/*(=B=FG4*)BE0=9*3"4);G"52!/7BE,+0!D,:A+@#?5H$A3?"8E7>+:'$>&:)9A#)2=H.!/()5>DAB>G5EG"+>-A2)$=);5>>?')A?>';#5$+&H&H7C<0D(1AA)0'/!?;$%H!@$.:E3$,>
@r4862
TGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCG
+
C!31*80.%$2!FH;/#",3D)E:,C?C0)(!DA!2&>.;.&)-)/+@F&1F@1H+6F/'"&G$C;C06AC.82;2!89$G
@r4863
ATATCACNACGTGCGTGGAGGNCATCAAACCACGTCAAATAATCAA
+
$EC%6H#*62&$F,E3"6C!#B&A"6D+GA-5E>)-?/5%&H10HD
@r4864
CTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTAAAGTGGACGATGATAAATTCACTAAAT
+
D,3+;/7'5-F3=F-,F"89+=#E0%9"=&C59?0+"7%$C'8?B?:9>0D$6"B"E)-0<F426*
@r4865
TGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTNGATATAGTCATTAAGCCAAAATTTAAAAGGGATGTAAAAAAGGTTGCCAAGGATATTATTTTTA
+
-*A/EB&<?BC/"B.),A"00"-HG@D;;!"FF=C344F)+DD$-%=(3'8>E</1"'<)*?"..C$>>1<@B30HE33*B!:>$141!',95A:04H=*3%HDDE:*D6@!-B((/G'>@&8,03@A$;)'2&(03!"?3673;;0<1<(8F,!<<63>(#>%?#CA.GG3%A#)@=A"8>!(.BGH7->BH52$"8C?=+C>7@4-)3D3A!&!7"9%%B,H6:)9E<(11<?>&-5%"2*&#%("9C.?
@r4866
CCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAAC
+
6,81;90$0FDB&-=@75%E'40"4/()&244+360*(EGFF
@r4867
TGCAATGGCATATTGCANGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCG
+
0E)1F/+=B26/F(%.,$476"F*H'*0"0=:=8=4/AD+8-2@#!%9<?=%#8D/AE7!#,315,A!>":G.<$8)E);GD)-(*0-E62?"<<3F:#D21E9';@==5+H#--0."F'.2D:.2,220)23?!D(FF'FFD-/&%F
@r4868
TGCNNTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTTATACGCGGCAATTTCACCAATCCAGCCGATCAGCCTTTCCCGCTGNTCCTGACTGTTCNCGCCCAGAATAAAATCCATCGCTGACTGNGTATCCAGCTCACTCTCAATGGTGGCGGNATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCA
+
$'"&$+!$++%%*$)$!%*'#!$'"#!)'*#('!%'++&%#%+**$*!"''+&()(!'!!"%)$*('##"(('#&!'%"%()&)%)(*!(#%&&&''"&*"'(#$)($!')*%*!%&(*!%&$$*'%%!')"+*%)$'("*"()(*%!+'"')+'!(%!%"#(((&!!*%$$%*''+'$(#!(&((#&%&*+%!()")++$!()"#"%'#((%(")!$&$$$"%$#()((%+')
@r4869
GGNNACNTTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTTACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGNTGGCTNCCCTGGGGTTCGC
+
($)&)(&+**#(#)+"(&##%*(*!(&(*$!!+(&&'#+%*"%$!(&&*+*&%+$)$"$("'!%!%#&*%$'&++"&$$()'$)#!*%$*#"%$'%"*#+%&+'"+')'%'!+#)&)$))
@r4870
TTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTGNNGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGA
+
7$C,.>#AH8)8/>D@<>5-""(?-'&4E;+<C)"=17CB0$')D=E%9(./8*E>"*?F+:8!'+>17B8B+!$?@.),(E$'+=(&2E6=D<*H>/+"H$2/:0-8=9?4(.!79*H2!(&H=9!-5&$-.3&@<:7-D(-8EC1
@r4871
CATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTNAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGT
+
C8)=@#/?D)@.,<-$E/=@ADA+G)+AD891"-43"+-#-<D10<.H?B:->A?A;#&::."8($3?('59E<F-)9G(&H;H'&;H!)&)/+.%(>B)19)3#85D5C'CFB9?>25)/*7')@!181$@=!G;1";'"F-CH9.4>3.FD1%HBB$A//02!5'<5
@r4872
TACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGG
+
4H/#@.3;04;D;6'G/*E0/!:54G-H>8A.)(5-#=HCD+.09C+FFB%?27;"GE29@?G)0H?7''F=-)/?*D#(=1:G."*)0<&"?"6D);-(1=;'%101!F*=;FA.8((.H,9"-/CE-69.E:'"3?(":F1#:)C04H!1(3E=$"1456
@r4873
NTCNNGANATCNTNTGCANAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAG
+
$"'!#!!))#$!"$%)*&$'&+*%%(##%)"+"#')!*#)&!"#!#!()*+#%"#$!#%"'("%'#%*'))%**)+'"(&)%%$#&"*'+!*(%'+"'+*%$*))$!'$")+#%'"*
@r4874
CATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGA
+
9:*?;:;0/'D'(6&7;#7"2G;?/C9#97"&G!4493@:+,6AAE4.B0*:6!DG.&;@7E$EA74=#?>E@F?C+:-3)!267'3$AGE;7D()$HA6%6G5.+"?78CD>%46.2*?+2-(#(1,?",70<:<'H,.2>?-;B:G($<)2.&72,D43+</8D$58<,2D,',<?*<@G>H0455)-%>F/>7.AF95&FDH4<(3<#0!E682*GF&C7&!-=F65">+,=!
@r4875
GGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCTGGGTNGATANCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCAC
+
,*4B-E?$GCAA<&B1%''7"4$3&;*"DC.G$;$!7EBE;D0&7=E&FD%E?(0%645(.D&(1%,#A$&B:A:))+;A1%CB>=@H/9;?9?)?&)8D(HC15=;!;*!=A4F(<?7<(->)60?<13A+'0#E**.>AD8"?%1)%>9A!$AF99-16)>
@r4876
TCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAATCACCTCATTACCGTTGCCACCGCCTCGCAGANCGGGCATTCCCTGTTTCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCNGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGANAAAAACAGAGAAAGGAAACGACAGAGGNCAAA
+
!))10/1:+;37$?1;!&.65H$F,G";'10(A=)9H9?=&D(=C!8291@B;#5;F&*;+)%?H*;;F/8,@>(H8B3;&--?)FH+:G?'5%-;;/*813!2?@*/%5)-GD;G"D&1E%=9.&;HD:)-191.@*4-D8?$EDF*/13'7-D9:A.G+81:(FE!7&<591/';0D4?'=/)B<1D/-0=%6%.,79.#41,%)$>$=5"6;=>2+?C:=3&=(!(--0%B$)G:+&+<%3/0HD6B.'F.:*))
@r4877
AGGTTGCATGCTAGATGCTGATATATATTAGAGGTGATAAAATTAACTGCTTAACTGTCAAAGTAATACAAGTTGTTNGATCTTTGCAATNATTC
+
:B,E2#;DB8-HG)>08%""G,5'2%+9C9'!)@(9*=:C2C-;5%,'??&EGGE'9"(ECGA%8A7+=">*!H&F<=E#'+7)E7E?)D&#H/8
@r4878
GGAACNGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGGATCAGGCGGATATCGTTAG
+
)("''(*&)+%$$#&((!$&)(!%%#&&)%#)*#+$#)&#"')#"($'!!(+##+%+&"))&$$(*
@r4879
TGNNTCNTTCTTCGGTTGTTTACCCGNAAGCGCGTTAGTCATGGNGGTAGCAAAATCTGGATCATTNCCGAGCGCTGCGGCCAGTTCATTCACCGTATTCAGTGCGTCAGNTGACGCGTCGATAACATCTGCAATCGCGGCCAGTAAAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCATGAGCGCGGNTGGTGCTGTTGGCGTTCCGGTNAGT
+
(!$%"#$#*+#*+(**!&&%$+(($*$('#'+(%*(+%&&+()()+")!+#)(")"&((('*%###&*)#$+(+)*$)$($#)(#*$#!('#)"!"*'%'%("+%""*)$%$+$"$(+%#)#%*)!($&'+#''"&(#+$$&#$+&$"*+)%")#!'!')$&(&+(#++)+&!%%$"$*#(%"("'"'$"#%*(+&%(*"$*%)")"$)&%"!*!$$**#
@r4880
CACGANGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGCACTGTTTGCAGGCAGACCGGTATAAG
+
?>+7E)&9#;3!1:AH;G%%D9"3<4(9B;+C2*8&%=F0A@46%)&5:&B?9+C$3+=60=,@@?2':6/'1,E<106H8/%!>";18&/>*6
@r4881
CCTGAAGAGCTAATCGNTCGGCGATACTATATATGCATTAATAGACTATATNGTTGGTATAAACAGTG
+
;%;&'3>67:8)<1A@>*+G-()=!-#/7@%42;242:('EH;8CD!4C6=C?5$+=A%B##%*:C(D
@r4882
ACCAGACCCGCCGCCTGAAAGAGAACCTGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGNTGCGTATAAGAAAGCAGACGACATCTGGAATCT
+
=0G:":2/79D:@2*:1C3EDEH5$A&;%@%2&@$'1)D15H*"HB6#+6H&>;G%H2=*9'"(F<477;,"@>G)650F122:"D-,3$#G$*)4E2,+3$G8)%*836A<,>%A8>$<E,&3A.0)6D&%,B"AA;4E4:1.4.A22,8-7D;>.+?%29F,*8=G/$-G2F8";H
@r4883
CCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCNCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTG
+
4">8@:+>9DCE%HEH(*(>1<-,(@,H720=5:482=<0D";?A:D!15&6"7(93@2D25;5<GA8806<#,H:"D$:9G:9;>C2$C%!$!H!?=F/,7>?3GB95@7-("),@(#2!0)(3)44-7H!,9.!G%-'&8.@5#5&6!
@r4884
ACGGGANNNNNNGGGANANTTCNCCNAGNNCNNNNANNGNNNGANNNNCCNNNNCNTNNNNNCCACNGNNNNNNTNGCNNNANCCTANNNNTCNNGGATNNGNGCCANNCGANGGTAGNANNTATNNNTAGANTGGAACATNNGNAGNGATNCNCNNCATCNNNTCTNNCGNNTNGNNCATAATNNNCNACNNNNATGNGANNNATATCNNNCNNAGCNNNGTCAGNACNNGNTNAGNNAGACNCACCNCTNNTNTANTNNCNTNNNANGGTNNGGNNNNNANNAAANNNGCANNGANGNA
+
#$$#$##!#"!$$!#$#$##"$#$"#"$$$!#"$#$"""!$!!""#"$$"!#!!$"!!$#!$""$$#$!!#$!$#!$#!"""!##!#!!#"$$""!$"#""#"#$#!#"#$$"!#$$#!"#!$"#"!!"#$!##$$""!!$##""$$!$##!#"!"!#!"$"#!$"$$#$$!"#!$$$#"#$""!"!#!"!#$#!$$$#$#!#!#!""!$!!"$!$#$""!#$$$!#!$#!#"#!$#$#$"#$##$""!"#!$$##$!""$$!!"!$"#"#"$"$$$$!"##$"!$!$!$$"$$!!##"!$
@r4885
TTATGTCGCGGGTATCGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATT
+
$*G/*('))+*!>.$H",(!E"12F=32CG?/H&#G#%#=7/#F"&1)=!5&;A>)504920;08#BB*4E0&>FF9(*)'$0/H(G
@r4886
GGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGCAGATCAGNACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTNATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGNGGAATGGGTAAAGGAAGCAGTAAGGGNCATACCCCGCGCGAA
+
0&B#2(A*;!C.B$%#<&+A<+!-//0D:7$A$FF1')H/8'G-%F/,G1.>-(4=+B7E&%/$F8(@4BE=4!.4"1E"&,G8#,)#0:E;??C%H4E9G&."DB+A"6)>F61:#*:A@BFB%5%D.C/.&A0EG/DD"1"F.$8D40<9))B"1;B.<&843?(?EG9..>9=8><>44F,(!):F=
@r4887
TTTTCTNCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTG
+
D.5<*8?A7.5+!.<3723D6DE:'5#58FE=;?!@82<#@;.':*'/<D'2,8544D)G3&0-6
@r4888
GGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACGTTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGC
+
%1(D<"49#8-"=6".6:-%41?3/EC!>8C$04@<"3G=A-A)0A2,/B.D=7"1CA?,)'/EF;7/9807*%>'/<"B=0C2&E:*?3)F&"?"*-E/&*A$?96D5%98.)&%E.3EFGG?=1E/.?+?*?2-.B1-3&$&%#G7D"7!0!%
@r4889
TTTCAGCATGAGAAATTGCCTNCGTGGGCCAGGTGGTAAGCACTTCCTGNTCAATCT
+
+5)@>1=;3G7@:=C4&0B)>7*G+"=CG/1*:@%?B20>G?%955%!@;0=G*E3>
@r4890
TCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAANNCCC
+
+2&&C<"!6H"$#.%%&)3:'!372D/<"B@><!!;FFH:/0H)4#=?;.=@/B4&",!@5%$9"=&DCEC,.0
@r4891
TTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTG
+
7/*48D?<'#&85>*5.:),B4B%<38%6.CE.8:C.!9D+A/4#3/&@8866*8,(883G?%B<;6>?5'(;C89H550;&2F9*-5B86)$
@r4892
CACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAG
+
.G70*,>7%)#+.51&,$7';52AC$@@C913;F8D41!@*$<!,<>%/;6H=B!/&$#=#,,H,>E>E49D&>#+<EB4E+*$B&-,!E5E!<
@r4893
CGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTTGTGCGAGGAAAACAAGGTGAT
+
2$<-C>*=D;#8GH*A"5F99<;;#29>F&::;>"=95=FEA7EG5BE9/D5*,1')
@r4894
GTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACG
+
&(4C4!.;#!5.-H0G:GG*-(%69)='G"(3*-8&G'!&=)"=$A=8!/3:C.844.F<EF&,"D
@r4895
ATCCNGCATGTGGAAAGTTCTACGGTCAAGAGAAGCAANAAATACTATACGTCCGGATATTGAGACTTTCGGTGAGAACTTAGGTGTTCTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACGACTTATTATCGCAGTCCGA
+
DHG0H6./0%76'6,F;1H7'+$<0=4=%,)/!&$>".%!>1>?'.//>CG(%03>-"6E>(4C7/;C3AE>,?.C4(D7;,E%=3!1-E<0?:A30=$-5<4;@12@.*3"="HH9",D>@B5H2G%B&)<G"6?AA-8#,7+'#"D<F1$A'14
@r4896
NCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAAC
+
$%*+("%&%'"+%&"()+"$()*$+'%)'+&'+%+%!)'+(()*)$#&$"&"*!!$)"$'$%)&$%!'&'&*%'((
@r4897
GTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATNGCATGAGTTGCCCATCGATATGGGCAACTCTATCT
+
++""(')%$#%*%*%&#)#$(("&&*!"(&"+&&((%"%)'$!&%%!$$%#+&)%*#+*$++))!$$$$#(!)%'('$&%*&#$'$+&!$##*$#(&"(#+**++#!()")$'($$$!$!&()%%*%#!!#$%)+$"$(&$&
@r4898
NCANNTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAG
+
)*)#&++#"*+*'$)$$(%++"$'&(!(+$"*#"$"#"!"())&&*%&+#%')+"$&++*#**
@r4899
CACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATG
+
(+!)"+!*#)+'*%!'"+!))*$+$#'$"$'#%(+%!!$)!&!%+!+&$&%&++++(($(
@r4900
CACCCTGCATTTCTNCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCAC
+
65C4H6H,>;4'0/H*+#9&$3E:CED'-.@;H@=D$3#F!%4EB9"18$<G'>9B,C?-F,:$FE40*19E"+/
@r4901
AGAGCTGGATGCGTGGATGGACTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACNAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGA
+
?&HE*$5A:E.-&9"#*/+,,""A#9)'8,<=54.!G40E:A920606/)--!:B>51)+27&3/D1DD82?G7*"G$#6G'..):@;0A8-DAC8#39,H?>E8,6%4,?(?>
@r4902
GCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCT
+
H.#.6D'?0="-0:A-H&AH=,-!*=.?8">):/E/#"C,+E%:!9*+==!F>;=,5
@r4903
CCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGACCGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTNA
+
F6>-(.?H0:6*+<D76?/07@5D@8/>/G>FE-70:,9H*,!1$:?#B2@$68,CG=%CG4,%3-$;:%FA+-:#)A@9,+70%';G><+@6(=4!4:5HD3>
@r4904
AGTCAGGGCNGCCGCAGTCACTCATTGTCCGGTACAGCCG
+
+'"$%&$"+"+($))#&#!&+%)++*+!%%'&(+()(%+!
@r4905
CCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTG
+
40?'B)(A&6.>C9#)&9;+<C<!*!,2A6%)B=B%'"AFA&DF+!5G3#?)C.-3+5
@r4906
NGNCCNTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAA
+
!%"''#+)!'%+)#"#&+(&'"###)!#%*!!!)&%"&#%+'%+&%&+)"''''!+"+%)(*$*$+$+'"*
@r4907
CGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCG
+
9GAC$279(&B4:(+B0".FD(2&,)H>7&-5F<@2#5D-3*?@+)A83G@5!:@(&08
@r4908
TCTAATCTGGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGG
+
2;?!1./?=#1D3F!;E7>2!472G+!F*'D$%<C?9+G3)@B-89+2+'
@r4909
TATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTNACATCACCGCCNANNGCT
+
)+*)*)*$++%)&#"+"**'%!+*'$*+)"+*)"*!&#)")#%#'+')'$')*%%)''#("!+#$*$"(
@r4910
GGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTT
+
=*;)GF4:7)1+B&#"&-@<F/E?":,!>E/?5H7F<;(G$1D"6.,270FG:
@r4911
TGCAGCCAGCGGNGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCNGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATAGCGGGGGTTTCTGCCAGCACGCGTGTCTGTTCTTCGCGTCCGTGAGCCTNCTCACAGTTGA
+
)(G>/#C<'+=H.*FA5=7"$;C*@F.&3F4E'1"'4EA<-)<3';/&4?'8H)#H0%7$B""<,/?@H<;&G$90?8%%3+@D=,(8E+'0)4,6EF.?CGF;164(9'$0-%84FEG.;.7DF%16F+!2*'##/*F?3*$2&/A<7<@#6*D%.;*A.1>%/H'(DG>F$/@'
@r4912
GAGGTGNTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCC
+
B5>G6.+9/)@F=)?%C32"3H32:4)E=+H3D9,D&)<H9<!"/'=
@r4913
NAGACAGNGNNTACCACCTNGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTCTGTGGTGNATAATGCCCCTGAACANACAGAGGACGCCGGGCCCNCAGACAGCCTGTTTCTGCGGGAAAGNGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACNGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGA
+
!'&"%'&%)!(++!()))#$&!'')*#&!#()!!(#+!&#"+%&(*()"'+%'!'"*!%(&&&$'%$+%$#*')'%*)"#*&+)'+("%#'#*%*&*!*%*%**&%+#(+(&!*&!'#&)&!()!%+(**#"*"))*)'"&!'+)#$'&$"%%"!%'&++*%"!&((+$%!)&%%$+&#$)&'%$(+&'##$)$)&'++)&'&"'#+$'*$*%))*$+%!"#*+"&&!#(")!(''%)$'*!)!'!(!))("$'&*%)$%))$*"#+)(+)('''+$&!$#"**$)+!$"(*(#(!+$)'#!"
@r4914
GTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTNTCGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCNTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCC
+
C5$.')>BC!>@$,5(!&/$#/+G.<9!0@94@#A+)8;##'97&-5+@&:(H9=-99."7>HG,A-?.9-"("!B)5GA>A@3'HH))**E)7:2$8;@/?F&*(,)?A8/'.D+("HC;#BH44'HA?2>;D<*,5<=,33%>,4+C6(78F-716?@*>'&0.A%B$A*$)6;'>6A612)%FC#27#8<'/5A7"5.?B'3H-%*60$=D"8A%C
@r4915
CCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCAC
+
0>+(D#/3#F!8>A4&'720=>F@+H+275?-/,5/.3%52!?8:7+=?-'1
@r4916
CGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGCTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGG
+
A+'3F9!CE#<%B<(%?+F$!'>+D!EA,@D6BG196*$,9;*;,<."EE&*>8)$57-GD41H<FH-)F1=,*+".,1<-7>B,=#,<#&>+-C4'-H<D:9:A5/4&DHF7=@)*C@#8*:7!11*+HH12@82
@r4917
NAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCG
+
"8/-"F)#EE62';G'<HEC)CFG?5F/1#&'9&$8C&GG(+/3D!@92DA(B&>6
@r4918
GGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATA
+
2A&4/!%.74=11E&;:H7B;H")-6C*DGGC;$.3,%>);;>$(?AD9)51!0C+-%2D5A6@6!BH:3(E<,5,BF'HG+<C=61!D--;D#-#>E#;(H615**!=5@CCHD*>:
@r4919
NGNNATGAATANTGTCTNCTCNNAGCAACTNNTCNNCTCTCNNCGCCAGACGGCATTTAA
+
'*!#%)&'(*$&)#''"$*$)$!'%(&$#%%!'*%!%%)&''"'$(++"&!$"#$*%!$#
@r4920
GAAGGGCTTTNCCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGC
+
8-1")H>5?B-HB?4F,BDE$($1G:7@=:-$:385BB?5"<F%;&A)H*5>?$'E6,%";*GD97*!B+28C37/H.-*@H,50!19@+$02)H;3;3'/67F@=9*$1%!-C"89%>);9BF:<+"0D64,1/1<=B
@r4921
GNATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAA
+
"*2=@G%:<"A?+H3/$GH2$F4G7!H/8E0D*)6@&D7-/E!#<(##,<F:3BGD0)(
@r4922
TGTTTCTGCGGGAAAGTGTTCGACGGTGAGCCGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACT
+
<A)*/H&B98@!4&>=G4BC;!F;0C3#"#G&H.9<*/1GD+D5'"-;8!/!7D1'@CG81E)G8;;4/,%==#E0"1B.!+0B=@)7A>8<EA9?@'G9,7.$F++6$@ED66,;F'B*/
@r4923
GCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGNATATCGTTAGCCCACCCAGCAAAATTCGGTTT
+
+&*$H59!6'"?+G%G(30CF%44/)G@F/$E!8;?+4%;?,,4,*#F@$+,6-;1)G=-.1(;"DH>>
@r4924
TTCANTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTC
+
248=/*243AAC591#13&G=G*4;+B/&/84/;7+.>)+2>#+*C!7;!0D564)'1;
@r4925
GTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATNGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCA
+
;H0%9C#$?0<0!:6FA,,!FB>!*8/3AH;=.@2,E4A!3;'H.$5B@2C<3<.F?:-%66C3>*=DG*<GCG/.68>9@.(B>1G01$416E1G$6F,-4*)82868+.(8D>%DAD,>2'EF>E8?&,7EC$&D/<&",=$(@,'<&?#@/#G%2#)17$
@r4926
NCCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTGCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGNGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCGGNCGCGTTTATTCAGCAACTGANAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATC
+
"1;&;G@DH&DG/.E5/7(!F+&3#8DCHB'/?&5$6*E=#26&)28"FA:/H.E-5E,757?;9+B.*H&#4?=E)-71@!8/!7>')8/B@G?235+4226'';',4D*2>4D:'*$+E&0$)30A45F8H?+6"!?"3&''08)#D4;F;C)+--":'*D9#28@A01B.&EB;!++C-%"E>D$8$/@@$'53)BB'-/@#H"&/@!(';!@0$G.2&,+=*2(7-
@r4927
CGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGT
+
8A+;@9D:E%17%;<"1<+5A@FBHH?'+$6D6('@#(;$
@r4928
AGATNAAAATAGGCGGCGCTTACTACCGANTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTT
+
60=F>'%&'7292+;5E.?@B03/%3##>76"2A9G8&&./',6B38#%6A?*C)BEDC;H5!21/<1BE2.>'$A5@HC/#AE=#F?)%'@4:*#@=#$3=$H&EA@#%#<D+!0A;8?7$2:1%>*>1+)2CF;3*#;&&:(+#F47
@r4929
ACATNCAGCTGACAGAGCNAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAGACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGNAATTGG
+
&($)"+!*&&$)'&#$$%($(+!*(+"'*(*"##*"+!($$%+&$%!)&)%*)!""&*!$%*'!+**!*&'$'$#+!*"#+)!%+)!#%&"$(#((#%##")**$*%$!*%%(*#"$'**)*)("&()""+%*$)()**#%
@r4930
CACGCCGCCGCGAACGTNGCGCAGNGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGT
+
5;$A(-H00A=#?32E2*,FDC*/97A,H,DB7'3.+GC#'G2+/"#F3(*$$$,%HE&-C""'
@r4931
TAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCNTCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGC
+
B:2A"&@<A'$&<"/D8D8%!=6B#-,E1":4$;/0%/&B'1'547)*23,B7%6,AG(06556H*?A>$-1F@;>1)$<!511",7&/<GF'+?..H/->D1;'70B@/6*FF68/C6>E*204:H""*"'==;/
@r4932
NCTGNAANACNCTNAGTCAAGCAGATAAGCGATNAGCTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACGATGCCATCANNNTATCGNGATGACAGAGGCAGGGAGTGGGACAAA
+
%')'"%*(*#!'&#&"(%*(&$+("%(!#))(!%)&)$(''%"+$*(&+&#*'!)*$%+))(''"$(&!%&*$!$)$+"!#$*++$"'*&(')#'"+#'!'+$*%('"&*&(+)!)(#%
@r4933
CTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCGTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATTACAA
+
3"#1"C9C.BA"CE&0CGF-%23BA6)#A#2H<B8$1H"=+29B3D+"#H@.!5D-/G>5&=C>GE#H81#+*F5/2*7?
@r4934
NCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGNCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTAC
+
$A(3!,'5%:3?E%5D5#4F)</$H-F&5;CB(H5%E208,B)8:/H8@F!#;05DA9),*.4DD--2,28FB2#2<+CC250%H$D!.;?;E@<7%C.<3)?A;HDA.*110@%65!*CB6'-1'"HA62C,733F:>59(B9+:$741G=/18(B2H"B8<A05#*&%?>=-<:=5'/1.6".?BC)6$!
@r4935
NTGCACACCGGCACGGCNGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGNAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACATTTCACCGTTAAAGGCGTGCATGGCCACACCT
+
!=E0FC%.C#D*1/1.-'7*?4H)>&B8G&G$E<39@>6/:1,G.!0<F0#D/-=!$G>)6!:E'*A6>:-57,(22G3=?<C6!@+.)#C0@?F2.=)*!D--%F')$34+$@A-;7@1@AH2$<)*349>EA3"!D>=G'6:FF.9=*=/H"1&'$79'!H
@r4936
TGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTAGCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTANGCTCAGGTGAGAACATCCCTGCCTGAACA
+
)85)C5HGF:;*=!A*:@G#%3<;4-=*,';!#GD7F/"8%*./;GGA+8)4-B>A#<(:;B/1":-<G#'<H8#@>*,71B?6661"B9*4&E=#9!BF2D<!@<@%'@1B69;<,*D5)/%6)$
@r4937
NTTTGCAATGGCGTACCTTNGCGGCAGATCTAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAAGGA
+
(;"7E-9-B5+<E%'+D4<F>?EF=)&&="'"+*;DB/129/2'?A;C(*(C*7.8!3-&D?$4-0#3AC25=>@;<=()6!DB9.2F:#:(#:144")<8:51+959=?8&DEA>E4@,=2!?:"&$24:3,=&:0%9;&5):8'D$$
@r4938
NGNATACGAGTTTGGANAGCCAGTTGATCATCAGCAGGTANTTTG
+
%&&+''*(((+()$#&$)!&(&(&'+##!(*+*'*#")'"$""))
@r4939
CGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTC
+
7E//.:."/2;6D-6?0;/%;?1(H@$9>EBAFA6<9;<G(E27,8A=7*
@r4940
GANGACGTAATGCTAATGACAGTATAAGAAGGGATCGCAGGNGGAGTCCGCTA
+
*!!#)%)%'+**$'!((+"'&$)"***%()%'*#(+!%+!*%!"%%+&#'(&#
@r4941
TTGGTAAGTTGTATTTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCC
+
&"!"*%*+%!%%!"#%'#""%+')#&!+#)(#)'(""'*!)(*###"!))$%*"')*"'*'""$"&%'')+!)"&)"!$"+%'#%"'*"*!&*'%++%%!'++'*('$()'!&"'&$$"+(#$))"&"+"&+*)*$)##()"!)#'**+(&$%+'%&*("+%!(**(%($'"((
@r4942
GGTGGAGTTTACGGCGACTTCCGTGTCTGACCTGAAAAAATNTATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACC
+
6%#DC-$-5<-)=134>"E@=/H+C+FA8/*'(8F?$>"3:4>3@%-7)<8;D9)&8&%%8)AB-8CE#36+9""G71C!:5G(>D/%6D%@9
@r4943
TGTGGCAGATCTCGATGATGGTTACGNCAGACTATCAAATATGCTGCTTGAGGCTTATTCG
+
(9.F"G%.">025(61C0@D69678(,+@=7F67*-2?4FHD;<'&9684F05;;8<&;0F
@r4944
AGTAACTCTNAANCTTATTAAAATAACCGCAATTTATTAGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCT
+
*(&#)("(#"(*""++&*+&''$##(+()+)'!+%$%)"%')#"*$+"'*&(%+*!*%+!('+)(+##)%&')(
@r4945
ANCTGNTGATCTGCGACTTATCTACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACNCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGA
+
4F-,9;859;24&(F?(",74&304+%/A,H(='.%?+>&B0'#D>249E$";$"?9F2'4E(A0.-&'1*+5-H/*B>$2@9AE";?!AF&3:+;5"$2;'CD=/7E&:1-D5@@C/*+*'
@r4946
TCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATNTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCAT
+
<&)=;80-@:&8B/#9G41E<E3&)%A/G;64%F,86'2"2.A(8>%!/=F;8$-+6+;,:D!:>E:4?E<!!8H4(:%#8C<;83?=004"G&6(GE%F<+&'2.7#',$'()>%&03)E=08!":7053EF829,D=,,*!*?(=A@F/(6'E!+6-+H"9A'GF43G.
@r4947
TCTGCNATTNTCANTTNNAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAAC
+
$#()($!%"%%#(!'"$"&*$&!$*+)+$+%())+%*'#++%'#+'$"*%
@r4948
CAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCNGCTGTGCCGCTGACAACGGCACCTGNTACAGCCCCGTCGCCTCCAGATTAT
+
E%9<$%7!8B/#*8&D534E(5E@,5.4(H$&)>@"E.FCB@2!>5/.G@84!B$+H59,,1=F$>F>&EF/23=5='?BEE!?6"D.)</E-;F/?.,0F0'>%E!?,-9D
@r4949
NNATNGNAANANANGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGA
+
($%"#&!%)!%'#$%+##(''&*$"(&&*&"&%$&*#)&)$&##&"!#&)'"
@r4950
AGATGAAGGTATAGATATAGAGTCGGCATACANATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAGTCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGT
+
<$/09F#-'.#%G7?7&2E?>;=F6$H$5B&"/?B"47H8?-AE(F5)H3AF0+7A+A/EE:6)'@,@'=E):GF+6@1(A2>%G"&7A86,:D6:58=/!9AD?E'6
@r4951
ATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCNCACTGCNACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCNGGCGCTTCAGGAACACGTCGTTCATGAATATCTGG
+
.-&D1G7E3?/B+4+?4DE-$>'("+65G65AB=DA;5A:,&(>G07#**1185%+)"GA!0)#!&B&C$0A*>3+H*H@9@)?*22"C57%DA*>=@/5C0:@(=/9"E2/(H.8>@H2-A;#158%2?'H=DDH&2CA5D?>11>!-8#(>:31=G-)*0.31CF'<EC
@r4952
ACGTTTCTCGTTAAGCTTTNTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAG
+
C93@(GA)/00D""*3$"9HC(B/B@&166C>6F":"8G(8#16?#<2C82##H-;@=D26*/9?5"E<FH@<$1?'
@r4953
CGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGNAATGAACAATGGAAG
+
%!78"87&#)'):,1-,0?4:B"2GH6F*A1'+2G";GEC=-G>899B?H3/+3A';F,=&%F*<'3&-4.5;6A9$#8
@r4954
TCCATTTACTATGNTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCC
+
95<;7D6-(EDH<1/2!?C<F;,H50)7A)BE84B%8'44&3>@G(G"'.H46&2EC8=4)=C":,D>1@733,CF;$F(@#4:F#E0819<(GB242#.;7B.A3C;&BD3<;-E3-1&?62>1E<=@#32,1?3CA/53H>G:DD&H5
@r4955
AGAACTCCGGACGCTGGAGAAGCNTGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCT
+
-+7-G.?3?8@<9":=41!D62D*9H.2:8=)%D;4(HAA309.8$)!'HF5)'E"*<19&=4<!&'>,<;G1;144.?DFE:1*#)C*7&&D0(A'$A49E53D-H#F#5D/=57?-=;@/'":;,/;.:4>.2',%;)'A-8@?)
@r4956
AACAAAACACAAGGAGGTCAGACCAGANTGAAACGATAAAAACGA
+
5#"?<GA04-.9$6=/=933".39E=/"("9;3E-<GF1C21+:4
@r4957
GAACGTGCTGCGGCTGGCNGGTGAACTTCCNATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTT
+
2;5*3;8/4?0,G+&8,-&"%-"*8F%"4-9($!E(.47GH#1+/!+*@.51$DG/@!24@=((6>285.@82*4;A)"C0+
@r4958
GAANCTNCACNGCNTNAGGNNAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTG
+
#*("("%'(!#$"!%#&$$(#+&)++$"+&'($&$+$#)$&%&++"%)&*+++%*&%*#%!"
@r4959
TATNCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGAT
+
.GC";@<>$&E3+BC(:(!3/-4."%7!CF1F4,+'8%>@76-G&42-44?3"<+$?6BB&)5=<5&)D89B#1A6
@r4960
GGTCACTGTTGCCCTGCGGCTGGTAATNGGTAAAGGTTTCTCTGCTCGTC
+
74E3D96;/8'4F<C?<:73+$CG(3%;<@"90*AB5)>4"1#H#=;#"=
@r4961
AGGNGTNANTANCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGTCGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCG
+
!$'(**&%!''!"$+!'!%%")+)(!%$$+&"%+%&%*&$%$*$$$)*$%(!$)('&%+!$("+()*!*#&&!(%++#$+'*!%#)%$%!)&*#"&%("''*!#)$((*%$$"%#"*'$"%*!'"(+&!)(+'!''#!*
@r4962
GACTTNANGCTNNNACCTTAGTAGTTGGTAACCTGACAAA
+
"!&#%"$)"'&#!"+'%)***)(*"*&$$$!)#&("&*!#
@r4963
CGTCCTCCACGGGTTCAAAAACGTGNATGAACGAGGCGCGCCCGCC
+
3B2C="/C478>>=*+:H)?2&7(E=/$=+9@5!??-=B4E/;49(
@r4964
GCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACNAGTGCCTGTACACAGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATCGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGANCCGGAGGAT
+
,4.!(#)>;.=&*;?18&+;0>+4*<".*3C11(F07=:)$:2::40B.'!E3A-')--&G.D+-!=9;H7B.((>65F@,'HC<*/.*&0H@B6%99$>6&E.*?#2.#$H$+D@6@@>!0(#;&(?::>:>6&1=B8D64(&D<FEAG&<?D!*F%02CE();$%?C<<?'!DBF0)6/73G+#C.C5$;C0B
@r4965
NCTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATNACGACNCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGCGNTGTTTTTACAAAATCCGGT
+
#<"F!D/)GDF5>:$7/!+86>):>G3!D/($<<0@?C3CC2,=.72G>3"=)3*/?B,5':(EC6$42*)"%)1C35E<G;(9%712G4A9H?'4#.D!8!HB+4G91%2@%2/C$
@r4966
TAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATA
+
G'>%=:6)'H*!=8+5):06,/*E=9*BA01H650!<:""0!E2G>
@r4967
NCTNNNAGCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGNTTCNGCATCAATAGAAGAATTACAGAGCAACACAGCAATAAAAATNCGCCGCCTGAACCACCAGGCTATATCTGCCNCTC
+
)$"!%&*'&+*!!+'+)'")())&&**!)!&$!'!)*')%("($)!%!'!&%$%##)&*!*#('!"*)+*+)()%*)+*)'%$!"(&+!(#**$*$*(+#)"!(#%'&%"&%$%&)#&''+"&*"%)##$!%))))+*%)('%%%
@r4968
ATTCCGCCTCATACCNGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGAC
+
(H3>*""/%6'G?><A8:'+5@H?:7,30?.*<&FG7*0E4#0)&(!1%&$=?;;B%)"#9/:F==$@1G;04?B5D7-*HE:;9@%A'D&1D%5*2.<+(+.!')/>/A&9DF"8.+1;3!!'*H)H+1/59355#4$%"
@r4969
ACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGC
+
74*9!0-!:!9&*47H="CF=-C)91/@0G:;@4&(>H)H585,-
@r4970
ACCAACGATATAGTCTATTAATGCATATATAGTTTCGCCGA
+
,0'H?68)6F?F#&E'HF8'(*.2*'$?D%-!02G$B6@>0
@r4971
NGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGC
+
%-)%;:<'"F*&6$2"3?G,").G%1(=+-0=.;/&0!)8=0F4$0%2F3.CAEE5/@G>E!G+5$3?<,#7/%-#A%(A9A%B6
@r4972
NCGANNNTGNNNGGGGANTNTCNGANNNNNNCNNGNCNCAGNNNNGNCNNCNNTNTGGCGNTATTNNCNTNTNNNNNTCCNNCGNNGNNGNANANCCTNANAGNCNANANCTGNANANANGNNNNNCNCNANGNNNACCNNNCCNNNNNTTNN
+
!!#$""!$##!#$#"#!"""$#"!###$$!#$"$"#$!"##$$#$$""#$#$"#!"$#!"!!####$!!"##"#""!""$!!#"!"!#$!$"$$#""$#"##$"!"$#"$!"#$##$"#$#!!!!!"!#"$!$$#"$!#"!!$#!"$""#"#$
@r4973
AATCAACNGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAA
+
0#@!;F?02A0%7-0/8&:H?9G9C5==)+##"BF3#+-<!=7&27<=F<B%5+)EFH@E3G&1=/CA%%57+/!=(C!#H4;'F5'$<'
@r4974
AAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAA
+
H+GF2#D3&&,>:"7+-%=#F>+#!@.C&?($".:G2E,BD24D00A=:5'8$9-##/;G$:/H32:;<#F;%<0:<=(0
@r4975
CGCNATNTCCTCGGTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTNTCTTTCCCGTTCATCCAGCAGTTCCNGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCNCTTCACGCAGTGCCTGAGAGTTAANTNCGCTCACTTCGAACCTCTCNGTTTACTGATAAGTTCCAGATCCTCCTGGCAACT
+
A?;DC47;?-,#(74*8(<:)%'A#')@88*92+4H<60B7);5+FG-!E'-B;3%>A;62'@8?8"(%3.%6&<B(A%>&5C$>(F?2(9%(H(%23#GF174:BA$=.GB-H@<8GG+AE%G0"?&548A4*5FB@"FC<+255-0:$9=HF"%#1$6(D"-B0F:?7C'15C%1A(!!$/-7"2>2#.E<)B$*%:%2@A.CF3'?6C',@-!<$8&5FH"GGA4&,&1;
@r4976
AACGNTCANNNANTNCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGNGCGATNANCAAGNCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATG
+
*#!*""&%!"&%!*"($'%+%&+!*(#+&%"%)'""**)+()%'!**(!++)*)$*'*"$'"&((""#'!#'("*!&$!(%&+(!"&'+++*+*""!%*('+((+"!($(%!++&'!&%#%
@r4977
ATCCGGNAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGNAGAAACCTCGTTGCTGGNAGCCTGGAAGAAGT
+
24-C9''@$9=AG58,&EE6A>4/->'>03C7<&1B9G#)!$%B8D:C.!8FH><,=.52#&GE>'<;'3*(<=((?33&E?E;GAHH>)<*1A2A"9C6;=3#C7(H@-F$9D?573/?<F"H126+&'@;#
@r4978
GGNAACATGGNANNAGGTGCTATGAAGCCANGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAA
+
!*(%#%!*$!"*)##&&&#)"*#+""(&&%++*(**&+!#)*#"($%#!)%'#$("&'"*'(!$%&"%&+'$%'#'#+$#")&&#'$#
@r4979
NGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGG
+
$E7@3G+3HE=5D#D<!##+4?;8$6"&?0(#4C/.-'5B5,!<4GB(..H(@!*
@r4980
AATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTG
+
#3G%8*7E95E:'HD<!>H51%H";-&-HE,/=$G<"<&D4@
@r4981
CGGGCTATTTTCAGATGACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGNACAGTTTGAGTTCTGGTTCTCGGAAA
+
D@8E)H:8.77;A0>07*/-,G@(G<65!%HF35C'G0=0,71(*)2!G3,!'H639:=6@8FAD)=8::A@4C)4F>89!
@r4982
CCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATG
+
"B;G?:D&:+3C$-B(&#H/*&#<>#'<:DA3$7;.:%H,2H6@:EC,!A@;@A"F"@!>$48:-6GFG-H&A
@r4983
AAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGT
+
$DGG4%$.,%5@-%'4"DE$7!D!5?3!:D1<@*+>$+?DEC/6&(.H:'H*/>=>0$10'5D.G
@r4984
ATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGG
+
/=5C>H+C8C86;A56E"GE<943!,:>C@!:!C2@1;,,D63F%#/43F')E/96&E5CD9+FA'>"@H=/8EF5;!!>G"B%#-!$G:"%$#@>:7HH&
@r4985
TAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGNGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGNAACTATTACTAATGNATTNAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTC
+
,.+80114>!7FGF5C1BH.'!6D(0@A/@,F6=&93*>(#AD2-G/?9@1B/8?!D%5::9DA5E><$A-F1$9#,5,+;3D''-8?D!=3D*%&%B7$/!<*"(F,9185>+EA7#/'.4>9!>7E</4*281DC1(A)6#(&E>C0E=0@:(?=E9$%G'0)A56G%,C;(+H=5.>7)--#;3=39B01E*$8''F&+2HD#<,EA,D)?2%-H0A'!'?<B,D)?=+9;EAA:9@98/(3C5G=2;7F676="*G?>9$;C)%5G&&;10,&=:>&-<C=
@r4986
NGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCAT
+
!?15@%=78-@1<5'.?8#?8%G*.<8)/).C;%9H11B=.()6!9#*&-'7
@r4987
GTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCT
+
4+GA43?C8=B)-.<G39/8A056E#>%&F+%/&&/4/;=1-C%"9A>6<A2>(E%&GA:/H>=.+.#CD:A6%0E:B6(:5;494$
@r4988
CCGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTC
+
5!>)/@+&4>1"?+;E'*5$&"/895@$,$C:/%%22=)+)7%08+3@EF61&
@r4989
TTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTGTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCNTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCNCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACNTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGNATCGGTGATTCTGTCCA
+
*&407!G:AB2C96"2#F-.+<6*H1"?8D!!.:?.):AH<(?GG;)+@7-9,C)$$1!23<+F0G)15.;-78<9!<"F/D1E9G>D/!&45+%A/$&H<4;+9,.=?.(6!/C+:8*0-E#E2D.>H+?D7(EF6*DFH9+C,<-,0D.:4/9(<!1(:""4:5".9A!#F:4-?E-9!D1+>$2$,"9,488)"??;>+16$-)81/G+%B,+;+*&?-05A&438()1EG1@EF27,4@'D161F2'B=%>1:<F2>;G9E3<;=5G!?4:C>H$-B1:23@?F%7%C2DA73/"6D"B3H*'GHC;(=78:0G57?5<6/53C5>-<C9)G!8$"G11!75@8
@r4990
GCGTGAGTTTCCTGCTCCGTCTTACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTTACGCAACTGGCGCTGGGGAACGACAGGCTGACAGTCCGGNCGGTAAATGCGTGGGGGGAGCAGGGCGATCCGGCGT
+
)*(&(+)%#')%*&%&%%+#(#"%+$"%)$#+(%"*$$&#$''(%!&+$&"+'!&*)"#%+($!*$'$**')++**"&*+%"%'+!+%%%*!))%&$#!(!'$++"$%"$$(%%)$'+"'(*)('(#*"&'$+"+&&*"%$!"'%!"+#!'&+%$++"##+%)+)%$)!!*
@r4991
GGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCT
+
/!HD?"*A',2A@+$():>=)3<22=4.'4>/A*G3B($6$<*DF;3B?*,=GBBEG6:EB"C7F@90>GB#;=0$H*72D8.G&6'"&?47B#D#)1!5>B7%..==3/.4H$893GD;<>A(D+4G8!:+79093,))?0?5;+3%&:A5*G$5.(D&
@r4992
GTGGGTTTATAAGGGGAGCGGTGACCCNTACGCGAATCCCCTTTCAGACGNTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCC
+
5FECE-#6FG?H=C,FC&D&#C?.G1(@F&!G'-A4"57=H)*$3!)"BEG"=494<7B-5-3*D);+5GD5,A#+=3(./F1*G3&A(*
@r4993
CTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGA
+
4!#(/FA85428'@CEE>GF:B$G/<8*H"8,:*8%=BH::+0#5/">$E<6<H&':*<;4B>6"694/:AE,-,!;F<,#(665#;,==+-+/,H*12<',50(+&02<;)D5/6,"7)0"F"0AF0#$7##G*AA;5))%%:C+.#D>?:973-$2%E)#G;D.%++-6F3)/1-@<#%G50&6938H&,";#8*C,26%*@17#.G>8F/<0*9::C3,G,E*HF=B=C=,9C80E+$6.H@77,FA>-;(;0H.79914@6"1#*9:$+">/$%'?G'/4':17455D337C4>+
@r4994
GTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGT
+
$';9H"4*2$6B-.',(A<?H+$8?:)!@.E$?+()A3&66H/!+95"G7:/$6+<+
@r4995
GTGGAGTTTACGGCCNCTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCA
+
/+7B):B,'&E:0G1F(8GBAB#.&""C:*AHDA'D($A/;/E:>2+E(3)?)2%3<7:E%7A0?%1'=,>4(,7AE5.;,G)+%,(%9&A,8$4D4-!F$+/'<8%F><A(3.,)%CE0FG,A-$@<B
@r4996
TAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTAT
+
#"+*!$%$+**#'&"!(%(%$!")+$"!"()&!&(%&)%)#&"&+$+*$!$%"&%"!$!%%%+!**!
@r4997
NNNCTGNANATATCCATGAACATAANAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAG
+
"%&'$%$%+*$$$(!%$')+#)!$#)%%#)+&#"*%"#&&%!(+!'')!"'%*('$%"*+%")"(!(""+""!(!)!
@r4998
GAANNGACGCTGAAAAAGCCGAANCAGTCCAGCGTGAAGGTGTNTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTNAGGCAGAACT
+
&%)"+*#!!&&'(""'$$$#*)%''$'$')""*$+&(*%'#$*#"&#$"+#"&'(*)((#%"*#($#+!+**"#%(+"*)")'()%!#'+*++(*%$'+%*&++$
@r4999
NATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCACGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGG
+
)$+(*)#')!)!+!'#$)!#"&%%"$+(#*()+"#+!"*#!&!!')'%+#!"#&((!(*%&$!#*"+#$&)#%&*'($")&&$+$"$#&$%*!'#%((%#!)!&&$!!(&%"&)"$*!#""*+&*%#*'+(+*&)"*(*%++*#)+)!%*$"$*%&'($(&%)$$#)'))"'#)
@r5000
GGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACG
+
*@9&?801"*?5.*1&B>&95"/90"<&C3DG#<13-%;$94'"9+BG.=8.:1+',<$5
@r5001
TCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAA
+
*"+)+*&++$(#&#!"+*!($$(+*%*#)#$")&!+#)"$#*$+"(++#!(#'#!"
@r5002
NCGTATGGAGTGCCATATTTCTTTACCATANCGATAAATGGCTTC
+
!+&!'((%$!$&&"*%*)&+"!'&&%&*(%&&('"'&)**#!!#'
@r5003
GCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCT
+
CE:+$,/0;?1/<B#7!5(G@E34C#H2-$D4%C,GG/&"&(49#:E6(
@r5004
GAGGCAGGGAGTGGGACAAAACTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTG
+
=("0'88@E@*#)485077%0<)67C'"D;*:,"!+:8>'!+<4BG7E'H>B+-AE/,DG>A$A,/143#?(%F45H.<3
@r5005
GGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGNGTATGAAGAGTGAAGGCCT
+
;!8'8@48C(9<@1F@:C5?/.),(>!"$(6:.03!2&9C9)EC-#"'::+33.;E*D9*(#3
@r5006
TTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAG
+
3B7+5&-;9>:5@-G*A,C6?'B@>1E(;AB4?689&@.2:4).%+%?D:6"':H7:C0@;@1A
@r5007
GACCATACTGGTGATCAAATCTGACNGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCAC
+
!:B-G%/69=B,1C?BH,0.B$."#"2!C<8>1G5&0?B)BB:*"?($0H8*)4%-/>55#=?G$>D/*-,92
@r5008
CGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGG
+
(-778@(!!3A7/:G0-3H&8''1@0D*"0".>+CG#"%'5$**.*!;
@r5009
CTGAATACACGGGCGAAGANCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGT
+
B3B%B%5$@7/E.*1-1CG/>47-5+4CD);8"$C:*E90C>&B@>-90;@./;0!,12*2
@r5010
TAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACG
+
C.9081;)9,(1)2=.8':GFEA5C4!B>$$ED2?BA,45G$!
@r5011
ATGCCTACTTTATAGAGCATAAGCAGNGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGNCGAGAACTTTNTGAAAACCCACGTTGAGCCGACTTTTCGTGATAATCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCAC
+
E!2(BC>,/143!19*G="2.0AB,H.:@$8"4?$:<,%?"2'%$;.5*?>"5>H16*/47BD:1&580@&?'H2D!+D#&4-B7=E.G40#.CE8/'E5B/=01#='4+F?(;A?!8H-E7,E63AGA?:-'8''<9733!F"+/B?@+A/@1(B/*93AEA;C;,;B
@r5012
GCGGCTGCAGGTGCAGAGTGATTTGCCGTGNTGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTG
+
+*$+#+#%!($($(!"%"&%)#$$*$+#(!+*'+(%$*&(&!")#%'*!#%'&$'%+%%#!)#&)'&&+)+'
@r5013
TGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGT
+
32+!=85C8,;?-H@)?13E727&@>5@7<?:%:95G*3H,1#!89<)5/%GH-6
@r5014
CAGCTAATCCGGAATCGCACTTACGGCCAATNCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCC
+
88:)-EA>3?F"'#/"-/!"@@*;98,$A<0'G0?A#6<H;G/>(!A$B/;(9A@?5.?.B1H3<#B63=B/&'>56==0'
@r5015
TNAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGNGTGGCCTGCTGTCCCTGTTATGAAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGT
+
%"+%$!!&(!&"%()*&&(++*$($+'$#%%$!"%%(($"!$"'(&'#*())$(%+(#)***')+(%$(#(%#*!)!!+#&%*&'"$"'+$+&"$"&$'"!$($))!!$))'*++%#*'+$"$""'("(*#+")#&&')+')&#'*(*(!$*$($##'+!)(%$%&""&*"'%*&$%)()'('$)')'!*%#+#(*)!#+*!$*)
@r5016
TGGTGGTTCAGGCGGTGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGNATCAATGANGTCTGNCATCNTNCATTAA
+
D='26D:?:.G8CC+GH1)31,E9%<,/.?=5&/EF4%=0')%4>92'18$5!($A-$$)):-"H7$-GAG$0"G@@%0E4C33)3):45
@r5017
CCAATGTGGGACGTCCGTCGATGGNAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACG
+
EC3.::B3G19*9!$-!</H#4FE75?D/:=2,1=)A=15.?*:7@-(FD!&*D8FC:*1+=<,1/1F$G8
@r5018
CNTTTTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGANGAGTTCCATATT
+
$!$"*'%$+*%!&+)#"**'"##'#$""'"!!#%*'!+$%*#!!!!#')"(&"$"$"%%&(%#%''"++#(#'**'+#%+&''&#!+*)+$$'$"%!#%#!!&+&*'!
@r5019
NCNGCNNTNCCTTCTGATACTGGCATCTNCATNACGTCATCCTCNG
+
$#%&(!#&*+)*#!%(%(+!"#!)(%**)"+*%'&)'($")!'*!(
@r5020
GCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAA
+
.<A0"=7G!--:@7<*,5&;%:..$/@(=.2!#(,2+</&/
@r5021
NACANGNGANAATGTAANTTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTCGAGAAATTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGANTGCCCCANCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAANCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGNTNAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCANGTACTAAGGAGGTTGTATGGA
+
&'('*&!*)$(%!"#%$!")'*++"!)*+)!"#)"&"*$&")**'($'"&'!%(("#(%%$)'%"$*$&%(%())'(&!'#+%&"&$""#!*(%'!&%!))!$#"*$!!%&)"+("&)('#)$%%(#)'"*#!'""+$')"+*(&!#("&!'*&"+$%*#*'+)#$!'#+##&#!%%#"%"*(%&)#)*+#%&'&!))+%*&(##+)#()&'#%$$)+'!$+$!'#*+&!($"#!+!)&'&%'($*'"+!#+!%+*$'*'%"&)$+(%"!$'(%'$+')%%'+'*(+*!*")*($&"!#))%*"&#*('%"!()*'$")$+%%"&#!(+*%+#&)'&&#++"$*(*+&%!"'##!&%(""+**%$*&*%($*#'%&)(!($$+"#"*%(%$**$(*'+%"!'+"(+'''$'($!*#"**$$$!$(((""*$''!&
@r5022
AAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCAT
+
%8/$,,*#'@B9<F33&;&?63551'==&1$F>G8D+$D6=;)F(F'7E#DB=0%777B,'+-&.).*6?C8+3AHA8F"!3*E*676113:BC)4(D=GH)0'
@r5023
ACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTT
+
-@,4#4@3"(-4/$="14:3$9BD81(6#C,A3$!%H,*>#=CF?E!6:*$H86<):H,"1==#$7C(?)-..@%@*"&.809-2G:!
@r5024
GGAAGTGAGNAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGC
+
9'6(@H!G9;=<G$!'&GA:$8:7#&!0*1C'=FC%:95.1?,?+%4AH+4F")1?F2+F(2><8B"F:0*'
@r5025
CAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACNAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCG
+
.D4!.0GD$+96)'(2@=&8.!3%#)G<59AG)C/!39:?,?02'+2A?6D9-<7235E.H9B)-A,0D"60>A<-H>#7G,;(=8H</$7&3)'<+H:?$D="8A7=@43!4.4(#'"A(39!>#A2/-)<A</)!*:AA>;!@:FG))0%-*6!&!-E3#=3)=$;#*0A:70F:#?&H2F=,9>D>A/G4&CFF$*;"
@r5026
TGGGCNTCACTGCCGGGCGCTGGTTATGGTCAGTTCGCGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACC
+
A13C365$7CE;A,01"5$E8"D,8/--)/D-@!2!0H:&78F>>@9-H:AD'G')2H=&@7<@?,BC>H"'!*$,8GD%C%&>0@27""@8!2B0-4C.AC:5&-2CA4&6=."B,1G7?F@.&#H2,65)H6B--:*'586&'%1"!68E:1G*:D!)9;7G.+68G$!@"ED&:B*-B,,
@r5027
CGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACNGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGATAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGAT
+
3.4E1*EA*'!$=&>%-(9'1.=!G&F?1&6",C=<"E/852(365*EE=081+</%0)<-(""@#/%>A4?):6!=-1(372.#9)/D0D*<#4<*&D!)H=$7'E+@'$GG<%1+$"57))!EHH;/&&$!?',HD"%>E-0?55%1*4D?%&';<"&C+'GAG3A$>9&56F>!D++2<7!668;88<74/!%1-4++'#:'<6!08C46E0G8564&3&(!!<(2E4%0<H9*87*.>")12*>4%,&=>G+6>'0EH'!D/.&AHE-@
@r5028
CAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGTAAACACCGTCAAAAACATTGCATTTAACTATATTGTGA
+
A249&$9,2"2/8GAF&;>0>:)B603GE)<8)&)2'A&E6=;D#;55>66*93?G?;?#?2"8/:@G9G4$<7E><*--6A5H7%1401D=3HC26E"#0$"*D(/5=/=>742A.)$!8E00=F*B29
@r5029
TGNCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTT
+
&'"A8.64H0H=<B-#*9@:<)C-%0/G<7B29:GC.9*494A<"8;?=-8F/"/!3"5=09&*,'&>019$2=+A+**<2;0%C(?E96.F7!!$7)&;9,;FE:DAEG,/"1>$=+63@04>!?>;
@r5030
GCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAA
+
*C8-667-F25238)=5'?$70*7CE@"CG=:?0E?==G6,<,<#3#@%BC$#):&(8:B$46$GB=)2;GHD,*&$)<(
@r5031
TTATGTTNATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATNGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACNTTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAANACGGTGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGCCGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAANCTGAGCCA
+
7C,0D/@'8:?//@8)3%$0C$-HA++3-:11A&99%-+7!#*.6CFGH!DD+&G&'18@.DD%?;")2@@*+0A#&D87:A04=-/)>%F--DE#?>A%GC@3-86$,)C/:?==;A*GD!,/6A.51;7A@6CF!@.'A0<EDGH/'(:8!97#->0C7H$3>%*$>,G'E+;0-.@+.H?54#.;46(5H;"57,..ECA)%HB,&*'?(@%15A7E543.6A#+4D*F(00&%&F9"2D07A<A%8/2;<F?$0;;2C*?9DH'!74'$72$%$;%%8E(AA@3%5D(59,/($5C'+*5B0#AA,&'#.-B*H8;@72$G68/
@r5032
TCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTTTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCN
+
,@/?A0%)+)5G;)/#HDB&(B7HD,D6,5=!#>@<AG"'8AG5G<B-G7C-?9@C,%FBEA9!6E!-(1%:.BF18:B7BHH9+>8C(0C='A!*G>GB,D+!!:).16F(:
@r5033
GTNCTGNTTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTT
+
!'((%)$"+))%+!)&"+#*"%!'"$%*+$))(+*)"#")"$)$'#""!#*+$)'$+$$!+%+!+*$"%
@r5034
ATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAACGGCGCGGACACGTTCATCTTTGGT
+
.F92(A3D+71#&HH)#?23&&HE+6;:C%!&/;D0G!C5#(6&5'B/)0>-*,H==D%!,-+E2==<)<?#=A;55A607?8%A<HA@+%)>,>4%%54BEE*%::$,9!#7(@4*)0*H&/23;4"F,%"-F@:,0@-4C+"1)4H#4(D<=
@r5035
GGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTNGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCC
+
DG>0,=5.A7)":A%E9+-)"F*+5)6484&!E74"3F0&%E9'361:4.:.79&C+>!:FE0B/=188$$8%)B(H+/1>)7F+<D2&1=4C?A2'0*5*#2"(-#)B-,F/*29")&#E0E7#BC*BH3$
@r5036
GAGGAGGCCACGGTACTGGAGTCGTTTCCGGAAGAGCAGGGGGCTGGAAATCCTTT
+
F0";:*>5C;:*477C-"0@.?D%2@D=:%F%;3:)2-C>4.)0&</+146:,E+%
@r5037
GCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAAGTTGGA
+
A1*6)2.;G!/E2,F%#(2,'C6&.D0.?6C/:%:":03F.?&7>.>$-B!@>=#
@r5038
GNGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGC
+
'%+++%(!$"*"#$((#*)%*+!(!'+!'%%*"'''+!('&*#%(*#
@r5039
CTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGATTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTT
+
H-C$E1@D!#%-'#00F$B:6&97E*!FH>$<C/+;"38=%=<59"!5$EA);&2*=#813G*E%B4!;GB:EF6+B80@*5BFH"H6=<=;?&15?$GB()4(E*H&3+H,96C#07%>&6G9#(">BHEE68
@r5040
GNCAGNNNNCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGAT
+
)!))*(!&%'*$+()*!(+()&'&(++!!)"'!$!"&!'#)(%"**"""+#"!"$)+(%*)(*&%))+%'++%%#"'''&('""!
@r5041
NCCACGCCAATCTGGCTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGANTTTCGCCGCAGCGGCCTGA
+
#*+"+&)+!"!++)('%*#$#)'!!"(##"(%%&+&*")!(''!!'%)((%'"("(##!#))""&%'"#+%(*+(!++%!*#&&#+)$)'#&&#')#(&*!#&+#(!'*$'!**'(')$)&'+&')(#*""
@r5042
CCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAG
+
-9%*<.80#9F>@"-,&D1;:"2,*9@*H</*<)?!G>?>=+&G=)4309>9%'7?-G%2!D%.8&A1;H#-7#H<-:4)3"23E20<#+F,=/C7+F8*7<;)F
@r5043
TGTGGACATACTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTC
+
3#12&.$27G%CD,,HB&6!H43H',2;+5?CF'@8D@=B?G#;4)"!#@++!7:@75E:B*26!A@:9D$08>%>:,;+;/3BC:)!9>D=2)4*)BF0<3.>-2%%<?%$
@r5044
TTTAAAAAAGTCGTTTCTGCAAGCNTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTT
+
-;<G3%D.B$F5,DDF?317<6E5#"E>?40B3@D.9.2%#4C()##;G=?=4),&!H+G+10.9<*%=.DG/1%D-<=:D38=)-#G:&3-77%0D90<#51)5?/*-(H>C2'F!2/
@r5045
CTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTG
+
+G'%$".E-3;G#&0,*B'8H+/(-$/"#+GD"G)2521#&CHH"59?$,=2
@r5046
NAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTNTGTCAGGTTACCAACTACTAAGNTTGTAGGCTCAAGANGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTNTTCTTTCTGCAAANAAGTGGGGAAGTGAGTAATG
+
$(+&&"%'""$!'#$%*+'*"*""$(&+"&("$()#(++)$)*'$%$"($&$&)"(##&*'"%*$$"*$)''(*#%!%)!)"(%+*'('$%*&)!$!*#(+(%'''(+!((%!$("")#%$$++*$'('(&+$##'+)"!(*#+('+&$"+**+#%&(#+**&)*!*&*#&"(&(#$$$!"&!%)+()%*&!&&)$*$
@r5047
CACGGCTCTACCATATCTCCTATGNGCAACGTGTTAGCAGAGCCAAGCCANAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTNAGCAGTTAATTTTATCACC
+
!#E-;B,E@#%D*'/26)49A.%CE2D3;7GG!".E-E@<.BB-0"6%-&42.(;/F$H(>2>08D-F@D)E1&.:<6@'E!>2)G8.GC:*,#G<8#,6A(2E-$G=,8716!FC"2-&)->$;8B/G***3;A4B;@$E5D@$9B3>G2%413,*H).(42A668G:6ECF/3.+=->%2<%)+0EB,B#(#/.F(
@r5048
GCNATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTNATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAG
+
)%#8A251A.G@@C>;"B@G:G5*24?#;D!EG@>9&B'G%0622#8#G%2AF?9;F./>+42A?2HA&>@$6%4<CA<-5*!H'/*#EH$7E;8'?!,.H</$)<H8:)"3.H#:1:+72E0-9"H>=C$7-5,/6/C4<FHA8*66";2;ABG)'@,;;&E7'@$/HE0'
@r5049
NTATGGTTTCTCTGCCAAGNATCTCTTTGCATTTATCAAGTNTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGG
+
#26(#>G2A#;A5C>>,,8D:C1/5D2H8=2529FB529&!>%FDHF,#EE/!#:;(82E*->A#<12&D8A3%:&@AB$7@-;9!<*
@r5050
ATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACANAATGCCGCAGCCTGTTAACCTGACTGTNCGATAGATTCACTCAGCAACCCCGGTATCAGTTCATCTAGCGCGGCTGCTTTG
+
:0,C.G6(D=,(:82)94530H:A2/3#0B!;56=:.H6$6-$,E@E6HG";&@C6&*=9CB;0$"-5#4EG$(FG3?%DE/,)7?:>("01!-(,0FA0B:"21AD1'@@"2%E-@:1,8!#@%'CD.*+G&,@,7FE>>1BF6+
@r5051
TGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAA
+
)(4!E.5&+B#>D776<5+!'B+!<54?B,=%$6328#8*$%(=0=@H,4-/"+B<3%6-7(
@r5052
GCAATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCAC
+
&*$<:!:9!2)@,+:B%)!,*!6)!2E0"472,,#A37G,6&8:'B49+@@>.HF90+;)6,04(,87-1#"H(/--05'AA*3D:F=FF&>3:D6/1-(>H0$G$*'?G-C
@r5053
ACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGC
+
'A?977)9,.@+)<,/8=CF-4-?/7BE9E03A(F6'278?6@D-4CB".=:%5
@r5054
ACTNTTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCNTGCGATGGTTGNAGTTCCAGANGATACGTCGAAGTGAC
+
?83%/3B$#C0D%;!8B<D,801>E,"E2+#HC-'%)?13)GC!**GA,6+6AG>)5$/(#;G@24GA@.53C;'D*>6+B"#G%>2B
@r5055
ATCAAAGGTANAGTAATATCTTTTATGTTCATGGATATTTGTAACCC
+
0BC@?:9%D=!=&0(-!$%F754!!9-/+C@>(<);1)499)A(/,0
@r5056
TCTCAGAACGCTCGGTTGCCGCCNGGCGNTTTTTATTGGT
+
&.:47),<5'8H@@HE>5/6$383??>>(")2!!8E)1=F
@r5057
NCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACANGCGGGCCAATGCGC
+
%;5,D56"8=EB(D#-$+6@1F63+2)>#5%*=34H*;@/,.G&2%*0%#A=?"@#BF,665D9)>;6
@r5058
GACACCCNGCCCGGCTGCGATATACCGCAGCAGTGACTGCTCAAACAC
+
.*!1!6-H5(*-/459AB#E(1GH.5"&HE-,F++2H!/"H1%1>*C%
@r5059
CGTNGGCNANNNCNTACCTTCGATAACCAGAAGACCTGCC
+
%&*!!%#!$!"$*%&+&+&'))!!#(!$%#+*!"%)%%*#
@r5060
CCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCTTGCCGGGCTGAATGCCAACCTGAAAANGTACAGCGTGACGC
+
8>!:+&)@"0!@F%,%-D-&A@:!439:0C'(52&+?1E2H#1)-4FH<("2@18H576=(F<G,G#=?&+&G0!EGEH!)8H253@B12E%:E8&'""=B8<&B!=#D.G66BB
@r5061
CTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGT
+
>4!.A&%'"-@CE>:;0C'CB<,@%C,B%2:'7<:1C57B;BBC";E=6A10'>?=>,3:9D+4=>H6?5/=:A7*881<3A!76A4=4/6$?(E##184?'G(68#<*H*GF3(=1,$<C#
@r5062
GCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGT
+
</B(/@<%D'9"';%&-8F$!,,F4+58G8/!=&D0:,9C!>$65,("H0!"#A4H'67EF2F.=;&('<59D-(5
@r5063
ACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTT
+
A-'/-2H2,G-''447C#'!*3.E.=!3D3#,.2-(-3E'>@;6.%=/12E:!F/=1A@!?$.0,A>8B4#
@r5064
GCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGT
+
H&'*/A/?)<6/;250)76GF40:3#:<43#5:3D&#./HB!452%3/GB,?"9'@G2(C18E(?A"/1ED@'40/A(#E5!HEHFE7)<#$C&(2@".?-!8>#&=@/,H<1C,6%65;BG4*@<4BE!'H;A$#H9
@r5065
GAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGG
+
8&027$.8')?#3+A83.:9=/1B!.,8<82B47?9=90$&.7'=(@F?6C8:"#=.,$1@F(B@;8A"-)/6"+C@%.''23)B#1-13+00,6+;'B%,G,
@r5066
AACGTTGCGGTTGAACTATATTTCCTNATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAA
+
/,F.,?%*&@:E2=1%+/);0B8CE13-9(B'(D7@#&,7:F'/!6D(27"..7H)2+!3&GE-H,C'6GCEF?H49&C#(C1(&GE!'2;7+5?-+<99&C19G""E2=-CG"6<,6A%H6
@r5067
TCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCNGCAACATCATCACGCAGAGCATCATTTTCAGCTTTNGCATCAGCTAANTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATC
+
;=AEG0!/7>:>7*!#$%*@F:8$*/&?':B'-54*F06?D,#7.@'C;'>=BF8F/?,A">;C>.'@&''6#D=B1"#&:-37DB:D7(*0&E4>,?"(=E9A8E(!%/&"?466G3#.+#-B<7-4"+A,1H!12B*6G6-F52*C"3F@+:?DD5A"4)6."@D;;(&E+E52,A<=BE*@$@@=C&4@;,91B"2=
@r5068
TTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATT
+
G%FG79A>)*"(#E0#+A>"G:33!0-)C-45>'.F-*%1#.>C,/46,&D7+A:2A</"9AC036(;/;
@r5069
CNTGTCTTGTTCGATGAACTGCCGCCGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCNTCTTCACGGACTTCGTTGCTTTCC
+
"'.-#5-/@?B+?=0CD1,&&<E-*3:8/,8965<1-6?7C$?(HA%76E+E.H-/84#7)+76G@C?<$FD'/45%E81B'@=1596'E=>;G*<3;8#49/AC/(!E23FF4;#7<C420@+!$.*31
@r5070
AGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAANTTAACCTTTG
+
%A755D4#A"8*(E)+>H$HE366>8@A"><0>-G8"1<.91+E:*"D*%F6.:7:7&D
@r5071
TTTGGTTGTGCTTACCCATCTCTCCGCATCACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAG
+
$$8:A@$3G"30#1@C!1&E$&'+"/D6)G.&C<42F66"7$CD!<?E/:&C=$$7%58!25;?CC9"%F0B?=>H3.B#;1'+
@r5072
GCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGA
+
'&%B,CH(!$:@E5/<4F5"&=2;BB8GD9+0CC8A**B11@*E(7)?':'5%6%9&&*!#.'0EF2G!06D<>C/(*3:
@r5073
TTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTAC
+
,D(1:+3.G>2!%B$)GB&(#4>G5"(,D=;<8?333%++''>GDB6$)/3@&3F<%&+B3
@r5074
TATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTG
+
3C0/8=;4G3-";CF;':+#7G&(9=42=!G.=7.F,7!"4-6+@34>F$A/C,07F47E-+:4(;3%3+44<)=H2$
@r5075
ATCAAACTTAAATTTCNGCTCATTTGCCGCCAGCAGTGGGGCGGTTGTGTACATCGACGTAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGG
+
F9=!!EA%+=-9F$!H2(($0/F3&@&(BH>%8H-F:$;C=G0?(-#BCF?((%((/0>D";D=1&#3@"/,G-;F-"C!9$,F160B$5.?%8<:,@<BC5;#@*G$%+H5,<5="/2;H3A;'@,!,+B:<+3H38D(@!$4&DF3#AF5C+'.;*BH(FFC!A"A&34%F&
@r5076
CATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACNCGTGAACTTCCAGCACATGCAGCTT
+
C%EA%*<?@D0-?20DA13C5::1C>29(3E*;4#"'=9!%.D3F;;1/9(E!'1?E4%4:('35!5?C/+>.-DH$9C!4A"31$-"95()((=4"C(((>H;1H%:DA#*7G8%)66!8=446<551C9#G'04<G%;&
@r5077
CACCTGCTGGCTTGCTCCGAGTNCACCTGCACGCNGACCAGTGCCGTGTTCGGGTAGCACTGT
+
G.%'C&!:9$H+062.G>@4%7@8>@DD7H"&>#*H'(*2!>EC735/&>"-48B(>26A=8D
@r5078
TTTGATAGTCTGGCGTATCCATCATCGAGATCTGCCANATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCG
+
+%$"+!*%+#%!'*'!*##"%(""#!'+%(+%(*($%+&)'%%&!)#!(*%!+%!#))#&&+'!+*+$''+(
@r5079
CCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGNGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACG
+
D5)D$HA.;?/4+.&B*<$,4>E+&!)CH,5B;+!&6C.&F((!AE<009='-;.:*%/*-9=$B*F1>1;>8F;/81%*9>F*H@6@+-*A-H0-1F7&&-6/@<G9?9,<
@r5080
AGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCA
+
+$#*$"+''+!+!%!('&!!!'%&')##+*'#&!!++!!(#*#%&#&%+(%%+(*$%&)'#*"#%%!(!"*+$)#"''''""&(&((!$$"!*("&')+&'+*&%'#%(#%+%%($*(!$**&&*$(&)+'%!%$'!"+#)!**()'(*&*)!#+($**$#%!*!++*''+)#!&#!")$$((%*##&)*&*(++*""*+!!)$"$+)&
@r5081
TNCTGGCGCATAAAGATGAGACCCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGG
+
'%$++(%$#!(*+$*&*+)(&%")%'(#'&("+&($+*+&+'))")%%!+%("*)*$%*&$$(+$))"#!'&#%$
@r5082
NCTTTCCGGTGATCCGACNGGTTACAAATGCNTACACCATAGGTGTGGTTTAATTTG
+
+*(!'+*"+#&#'&"#+("*()'+!!*+$)!''"(%$!&$!*#*)*('&*+&'+'!"
@r5083
NAGAAGGAANACNCNAAANANTCGNCGNTNGNTNNNGNNNTN
+
#!#"##!!$!#!"!!$$#$$""$"$$#!"##"""!!##!#$"
@r5084
GCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGAC
+
G#*?D+9D;#BD7=9-@A54+.)2F>F;<4)05'<F.1)H.F%*#)!>0F*#-C(=!F'>A
@r5085
CNCGCNNCTTNGNAAGTAACGTTACCACGNNNCGAANGATGNNCNCTTTTANCNNGNANAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGT
+
$"($&$&"&*"*"'$)'%#$#&#"*!!*'&!)'$'&"&&*("('#*&#!#($)!&&!$!+&*(+$"'+()+!+"#*#)+(%%+&!()$(+&$(%*$+%$#"$#""+#"&((+!$%$&"%#!!+"#(!*%$(&'#*$%!')%!)
@r5086
TTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTC
+
&+*&%)()!'*$&#(+(!*"(!#")'$$))*!)+")$))*&'&!'
@r5087
CGNNNNANCNNTCANNGTTNNNATNNNGNGNTNNNNNNNNNNNGACTATNNGNNNNANTNGANGCANGNNNACNNGANCGAANGTNGCTCNNTNGCANCNNTNGANTNGNANCNNGGTAGNNTCGCTANNNNNNNNNNCAGTCNNTGNNTANGCNGNTGTTTNNNNNNANTNNGANNANNGNANNNCNTCNAGCACTNCNTGANNCNNNCNNNNNGANNNNAANGCGNNNGA
+
"$"#"#$""#"$$#!$!!!$"!#"$"!#!$"$$!!!!"!$"#"!#$$""!!##"!!#""#$$!!$#!!"#"!"$!"!"#"#"##$!#""##!##$!"""#$#!#$#"$$!!!"!##$"$$$"#$##""##$!#"#"#!$!$!$"#!$!#$"$!!!!!""$#"!!#$#!"##!#$#$#$!$#"$"#$$#!"!!###$$!#!#"##"$"!!$$!#$!$""##$#""#!!!!!""
@r5088
TTGTGGAGTTCAGCCGATCTGACTTATGNCATTACCTAAGAAATGTGANGACGCTNTGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCNGTGACNCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAATTAAAGACCTGACGCCCGGC
+
2(=7=!(%&$?9E<?(,#2D+)!."/DE!%3&<204353&0<5$H!38>H?@A/*B=;+52H8'"8,:;:;'9A+-B$FD=F>D0@#+'%=0>B6%#,1,)9@B"!"/.>C%$0,"#DA*78-:&1H%08"9+)-8!/%;,/2)8!?@:'E=>8+60!C7&;<E!4*)$#!7(+D(7H<C?;'E#!?C0#*5&?1,5@3
@r5089
GATNCTCTATCAGAACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCNTTCGTTGCAATTCCCAGATCTG
+
)!&"#&%!#*%(#+*)+"&"(+"()'$(+%)!"('$'!%("')&#*#!"$*"%%*#&$#!++&+'**$(*'+&*+*+++"%"&"!)%''"#
@r5090
ATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGANACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCNCTCAGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTNCACCACCGAGGTGCTGGCAGGCGTCACGGTCAT
+
@0$3;)9'35<&'/3!E,.)..2./'9E;,/;%%(%:H(2/F<EG@6*79?;"B!?=+<(9GGB"A3D2;;,B!CG,;7@:D='.-"0F:F%=$5!*5-77)F:(H829(2C>+HAA<9(=+/=">!%H>01DDE+>)<F,72;(<8&7A3&*"9'#'/>-5&B.68@%D!8@#B818'>>=$9E2/,%0:-'2;8=34
@r5091
ATTTCTGAAAGAGTTACCCCTCNAAGTAATGAGGGGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACT
+
GABGF$367;,D!H<.56635'/G7C611'A8!9'&(>B45!"2&54@4D#!"9#!!9=B+,"@C/>3'-'.:5<*!ADC-@.#
@r5092
AAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGANTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTA
+
F%47+/+FG"0'G:C,D0*+5'0/5600(GC:,D9;>&!0<<,,&!)+51=B!@/2!*,1#'71#0A=C$&A8>8GB!)3>+G=06&>@-->1&*:G%H8";C7F*>'?:A:$7!5"&2&>&D!+6>@3CG.1&;1,0<*@BD,0C4-.+G@E!D<++/='=')$H8B2&,;%%%(F33'8.+'-DD*E
@r5093
CCGCATAACCAGGAATGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGA
+
.8'),*)2*B-##1B?*,DH.*"35F:<>G8;@E;E/5)-6=<@1:H,156&CA'C/G@:0
@r5094
CGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATG
+
HA(F5+,-@)."&EHE'?0=41'<6;!'8G3&07>A)&21E?<'00=#)@2<@,'+"<'BC8,,<+@3/<!7$$0G93-9:/EG.)AA-2H"E7*G
@r5095
TGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCNTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCANTATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTNTTCTTAGCTTAAAT
+
6A%#)1&@A?//BBB?30)1B=<)21'(F')$7'3+;8?G1%"6D7>)G%%/@1=0;"B>-?D-=#3'*<.5F.C;E.;'/;+&:9(3#9G#,AG6>7:>=#?=$D#=<F"838C3.C.4"38G(H6B88.-D64<D:.F->.9-%=<$)F<7>!>5+!?6@*60G@-$:-35?'CE?2*HH!.6$$><)/3,("4<0<#EB,$#*<$#$0.,-:B73;1:F)GD*%$,!&85$)6<#>6,!93F=%<?=#%;+B:517;%:B$>1$HHE71?+<!61$=#.<.+DGB)<+$HC/6942+'1!"<11ED?-%0$-CF:0A*+H82HE@C*%C.>2-.H/&@2HD28A
@r5096
GNTGTCNGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGTGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGNCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGTGNA
+
$"%"'!*)+***&"'+*""&+#*"#!&*+!)%+)&&##**(&&$$)!*%%()!%'%+%*!!)$$)*'%"()(%"(!!$*"++#!'%#%(&)&&#%(+%&&#"%"!+"#%$*)))#!%"'!(#*!*+&)()%+$'()*)+&"'()*)#$*%%((%+*'*&'!*$%'(*'!'!%&&()))+$#&##+)!%)'()+((*!!")&%')''+
@r5097
ANNAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGAGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACT
+
(%!2;6$&.9.>1)0:F,$!*$B6!H*0-&C!25'-3-$((./-78?B=@5G%6A=(F.<#)(@1HCD3,8'#&1"7F:*,5$)+=HG"'++GD-D*>66,;('7
@r5098
AAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACNTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAANATCCCGCGTTCTTCCCTCCNAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCAT
+
#58$-0AC>:%1>F2?*#@,:(9"C6G+H%)B'*")&,$1#-;@#."+>A;<5,?1==;:$(0;:,;;@!0ACF)'=HA>6G30'!G(.G14E,F!/2?2F4/(0/.3=$)A@(3:?0,/-,5=&=*$H=C?#!:6&(&+4"<G-
@r5099
GNTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGG
+
(#+$"++#$$"&*&%'#&(#(%#$(*$'#()(*#+!+#*&&(%$(%'&#(&"%!$'""'*%)!"")!#()'#+(!&+(&$*"'+
@r5100
CAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACNGAAAGATTTGAAGTAATATTTTAACCG
+
G(F;:5(12;%E2/F0GH(<%H.9<B,B$3':6E32</9E1AD5D7/HC).E>'4,1%23=@"H)D
@r5101
TACACGGTCCGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGNCTCCCACG
+
"99?:&40@"=5/8;5;3C9@G#6:6(/-@*!=/"H4<8+2;F@:$3F5"-8)-7697#D&?4&(2152"<B70&'/;(B/<#%/F?72
@r5102
GAGCACAGCNGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGANTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACATAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGACTGCANTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCANCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCANAAAAAGCTAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGGAGCGTACTGAAGAAGCANCGCGAAACGGTAACGC
+
#1;&)"$:EB</A&G"B<G%H%><640?CG$:+9H+2(F6/:@8%%$/G/"5&A?6D0.D?E:$<#@;)2(F+,:</B%0F'H3H.@/2(2+""%@.<.-1%CAF,D!!8#23(!C'=@*G"5BG2*0/5'#5D1D!10>//=8GE.9D@:39E;H88)0>CA5D10#5"14DE+>7=(074E24/5D2&55@*@C<3CC7-B0491":/8?,=9A:/#EH>E)>A>33AH-1"F6((0!"0('1:(1('B/5EC2E29*+=0)%,F8'#%DC)?EB)>9AHB-1C,<H-#8>$78693"!:+3?!E%0090*>?,588!F*#.8*+4!+<?/*B1)F+E!2??,CC6+8%2!03+C8@,.=)B>!+$E/G*#DF"DC0#&$@10EE4!5*E-1AD>/"6(CB"(F1.3#.G&F-:EA?2/2?DE=??:3&.=,2(8E7"5($>">1B5:)B3#=&7$*5
@r5103
ACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTC
+
>9&29'%<1$<37;B+CE,=H"(6$2/=A)6AF2;*F5%/69%E88=/B-8CGH*7+3-'B1-86"DGD$;B>':-A$!$3<%!F:1#+.*7.50=09E7G2"$
@r5104
NTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTNAGTTCTTCCTGACGGGCG
+
-*!"@E(@A3EEF/H.(4/.H67&1=96'B6F0F@61G?!,2#!-:+?.'-?'#!*2H+>!
@r5105
GTTGACATGCCAGCNGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCNCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGC
+
?"!A6:.":9@)+77>9=2GD+@A<8;F4<0-#@/$)D#7,F<4<#*:##2&:;.>#)&<GD4B%-%&=G*7//0D.16G+$>'?<2%@'77F>.&D',*6&36HA".*0?C2HD'G7$<3.HHD%%#3111*H)
@r5106
GCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTA
+
F&>'B44,/BD!309!"!>!/8+?$%>C6@6"$BB4!F)#@FB6E+,2,
@r5107
GCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACNCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACA
+
96=G&#;E-(%A63,17+C@%-=E7<#'=F0:",E5;4H((HD.!:B$*F31B3<<E$$%*0@8:H<DF9BA0G14@2D-F;@!0.DG?04@".D#5F$64@=B/&%2<'2'=.2$4H2G@77,A?"'':<$+&?7>;D;6G4/D3'8+<"16D*-3>9B85(,87*@B3<7E(+6>;3'3E+<1!D-E,3/0=<1HE>022DG9-06.%?&>0?/*B2!&$?B8!*0D!96%4$,*,.D&9*;&-$6<1C?=H*,+8E1H4(FG"<987=H"C804C/E&=
@r5108
CCNGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAAG
+
))"%"%(!+%)"!&#($!%$"'*#(""(*%+(+')#%+'%&&!%&($*(
@r5109
ATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGNAGCGGCGT
+
067A;+<:!5);F'?2$(EF&#CHA.'D61"HA(!FG@8CBC<)E
@r5110
NGTNGNAGAGGGANTNGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTT
+
!'(('%')(#''(#))+%'++%)+$'%$#$+%'&)&!!%"')(+**($%*
@r5111
CTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCC
+
G-1C@AF3F$<B,+A!B6@+#@G18DG+4A/%%F3'#/=(18@#%'6,-9D3;-F>)<G<0@92'89-;-?&""+-0GA&H*C#=
@r5112
GACAGGAAGTTGTTTTACTGGTTNAGGGATCGCCTCACCACGATTAATTCTCGCAGTCATATGGACAAGCTCAT
+
DD)?:<'!=%,@"648HC&H71->EC4D"(B(%&9D@5*9@1,%A>>!F*2F'E$B367"!416!'!>.:)$"<
@r5113
CTGATTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCNCCTGTCAGATTGAGCGTGCAGCCA
+
B7B*F.C?8&!)*7,2E!5(/%;G.A.A?9*!&C$!21)',%$9,##51$!!?!70;>,(2<$#84;"$38CCD-<+84()("AA59)E!F:#,B%@G//EF+40/1+116BG:)()1E+3"$?--.!%G#?+('*(/"@,
@r5114
CCCGGCCGGAGGTGCTGCGTCGTCTTGANCTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACTGAGTACGGCAGAC
+
F$;<F!B@D/0&7,'*==0;/8@<7%'?8C;A-(!4%7358-"4?<?*(A2H(C.><1H@$/5E,/28H.9>&;0G,&!7?,C4!H
@r5115
CGGACGACCGCAGNGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGAT
+
1F/2B7)#<,5&+9(.<*0B(H80C@"(*:#E5/H%"$$.#127</B4,B6.9CC<@-%%9G'@/$35+$8)=)0#7FB7F$71.C@/6=326;7.2G1-#71&/6:5*,5!*#;C92H2-D-5F30;6&;
@r5116
GAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCNGA
+
;EC;<8HF'1G0D8BF4'B;@F&94<>?>+@2817.2#@92*(8C1G&.
@r5117
NNNCNNGNANTNNANACCNNNTNNGNTNNGNGNTNNANANTATCTNANATNCNAAGNCNTNGNGNAANNNTNTNNNANGNTGCNCNAANNGNCNTNCAANNGCNNGNNNCNNGNGNTNNATNNNGTNNNTNAANCGTNAGNGNNANCNNNANTCNTTANGGNTGTANNNNNNTNGNNNTNNNGNGNACGTTNNNNCNTNTTGTTNCNNGGCNNAANGTGNCTGCNNATCCCNGAANNCNNTNCGGNTAGAT
+
!$"!$##"!!""!$$$#$!!#$!"!!"#!$#$#"$!##!!#"$$"!"!$##"!"!$$"!#"#"#""$!"$"!!$!"$#$"$$!"##$##!!"!""$!$!!!$#"##$"#!#!"!"!$"!##"!#$""!$!"!""!"#$""!#$!!!!"!#$"$#!###!$$$$"$""""#$$!"$#!$""$"!""""$$!"!""!$!"!"$!#$""!#"$$!"##!"!#!!#$!!$!!#$!!"$#$#$"""!"#$!"$#!$
@r5118
TTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTNCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGNTGGAGGCAGACG
+
8F!9D%6-*FADFF#D!C9;9;=7%!(;-589><AFG3'>D*.C&*+:72#0+D0/2!3;@<-G.!+/64$AEH5#*'B/&-
@r5119
AAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGG
+
-$+.C(':,/5./C;>=DE:8C0+G1G(>79G$$;?A>(A&#<C%?9.?!3B?-?=60BHH1D7=0-
@r5120
TTAACATGCCGATTGNCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGA
+
$A>6;!(#3*;,,A359/;FE*,*/F,0B0+(4"7E9:>2!#DD7,1C*(+E8=(0$'++4.:@<'(<%-+#<'F6,,+@6?'DH3(6>$/$=E6G@&./G#3.1GE-%-5A$%!9+E!9@38E,35,!B9H!A&<)=+A/G%&!6%(,-*BB
@r5121
GGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGC
+
8/BG=7A@6?$%>7F1$@,!7@+CF<$-E'7<1))*4E:<)/*C6;:0!+7>>4#7%.#@,4&/#F3./D?0*
@r5122
TGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTC
+
8F!C@<73<1A'0=G+B218AF&3B!<2#=2$&356'69*G8%D:2)4D:'2%?4(*:)EG6)9.!:-1@D
@r5123
ATATGGCCTTCAGCTATTGCCTCTCNGAATGCATCGCTNAGTGTTGATCTGATTAAC
+
'%;990=F#H%149"46CFD1'AC*.A#<:$(:8343-</0.>"#5+8BC1%A/5D'
@r5124
ACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGAC
+
8B)11($1!FBGG?-!;(7B?<74B99/@!98)EC(?F#H(A84G69+2D3BGC?>FG=(+62>3<(4
@r5125
TCGGTTTGTCAGGGAAGTTGTGAANTTCTGGGATATACCGC
+
:>6@#'D=9$//B"<A3.C@H/;12.*8C5(3-&1%=*H""
@r5126
CGGNTTGGAGGANTTGATTCAAATTCAAGCGAAATAATTCAGGG
+
FF@AE+&D$/=HF'C./42H9*B5'7?C%);9*D<02B.3.0A6
@r5127
NTAAAGATCTCGGCGTATATCAAAGCGCGCTCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGG
+
"4.)34/9'298582AG=?<52$A$(4?$@':;9<"23@,$AB6=))F#/">)9@/>98A06/?)B3-!=1>$/>AH;5B*A;*#
@r5128
CCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTAT
+
7=7E+G@@'928-E51:D%5F740<2/,6"A.!4:4FA(&0/=@A
@r5129
CCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAA
+
;7F8)<4EF08!H4,+8<G:00';1DA!)B*7(+,&"?3$'?!590127#'$'2?1
@r5130
AACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGANAGTATGGGTATATGACATCGGTAGTTATTGTC
+
D3-5,$6@("#!+814$@#;%,)*!9?3>7>+1%82".05'5FD00(28BB&A8).@.#='H,*A+D(,G<B4?0&H*(--FEE&':$.B2!)D9&2"+=:47+.;7C2
@r5131
ATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGNCAGAGAACTTGGTAAACAGAACAACAAAGCTG
+
6"-DF"66"&E42/E@5H)/%,:A"72F%.6/,5%,)!=!-*D'$B>5;6F"80=CB5A&:5H.<2.63EF:A=6<**E>')D301,FB$1C-?6;A'$5B8<?#!'/)HF*/<:<48@A*0*%E*G;!@<7C;=C"5C*!&?C-"-0G,+08CF%1>506-!D9C>+GB+$@)E%8?'"+G8D+!:&+.:8;*#(2H2AC=A6/)')AA2D58F2$E#5F/'3G7>1DCA<&:1E?#2%:$D'*>*!);6EB*7:F1F(*@5)
@r5132
GCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGA
+
:"093G"E5>F5*5>+,>>1,./-?.D;%%D6A0+9!?&G1&38F&G)
@r5133
ACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGAC
+
+"&"'*+&#&!'!!+#"#)#'(*!$%&&$&'%%)$$'$((%'%#*(!*$%&!('$"+#')+!!"*+&$&("'!%"'**+'"&"!()(&$'(!+&"#*)&*)()(&&#
@r5134
GAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAA
+
,">*:&%:5.C;--835#!D1/@,8/FE-A%,&(2-H!66+C&;2B."3&%7<7'+3
@r5135
TTGTTGAGGTTTGCACCGGTGTGGCNCCGGNAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGNACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACT
+
+H=<%5<<2&/&&H(;?$6-.3<D;4*':;??*B6#%EB2$*51A0)F-3/0(45E7E)65!<E#.2?1-H!/%780>C%E@5&/C,$;5%?G?9D$,:AB)>$$'+5!86!7:9;"$'
@r5136
CCGTCCGGCCCCAGAAGGGTGGGAATGGTGNNCGTTTTCATACATAAAATCCTGCAGGTCCCC
+
;*ECG4/F+-11>.CE+&%#;=;*?9EB0G&$6"50955#2F5!1$+%4.7C04%!24'427(
@r5137
GGTNGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACANGCGCAACAGTNACCAGCATAAATCAGGCCGCGGCTAAACTGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTAGCGAACGGTGTATNACCGGATAGCTACNAGGGAAGAACGGGNAGGAAAGA
+
+'&"*"!*+($&$!"%(!$#'($$%%$&)&!*!!&#'!)'&""')&##&*'*#&*(%'&'&(%"&"')&%#%%'("$&'+#**+*!!!)(*&&(!!)!(+#!&+'(*"#+)&*&$*+#($+&*)&&$+*!+()!&)#%)"""()++((*#+&&+*$#&*+&"&%!"&*("'$(+'(&"$$*!!(+%)!*+!+'$*(&(#!!#!%&)")&!$*'$#*)('+'")+!'*%%!"))+*()'!'&*%"+'"%+"!)(**+%#(!&"")()"$)')$&!('&($%*)#%#%(#
@r5138
AGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTANATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAGTCCCGAAAAAAAAGCCGCACAGGCGGNCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAA
+
0":%B""F&*>@>:HA)H92<'>"#C4AH>=0<;9<#8C9#1<@6<*7%#C.%*-:&D2!:+2450H72<(?&60A1:0F<HD090B<!7$$826B8B6$'1CH&%19-,A#:,4@E6&HB:;!,/$+38-GH&%94;H20=AG12D*D7%F0GA129<-)5B!3,;%60-/$5$H",@
@r5139
TCAGTATCACCGCCAGTGGTATTTATGTCAACACCGNCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAG
+
4+D+F6B5@;)?98*D&7?:200&1&,>EBC$2+2=HB3HF6F+E=@>)BGG,GD*1$623CB/'719*+=B!#:8?&@@13-3%*4>';C6>=+-F<6H9:)*'(25A&!=9<1<8G!2A3'-!=39ADG5?:@:)BHB$&,06D04DF
@r5140
CTTTTCTGTTCGTTTCATCCNTTACCACCTTAACCGCCTTTGG
+
E:@(99;F#1*6<&-<4@)00:0+FH-G2=)2,H0+>-E66B'
@r5141
TCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACNTTACG
+
F?:1,7.7,;GC8:AA?'2'G4>51,>>)'+:.$G#*.9BFB#,F263'>$4@)C';8+!67B*!&>3
@r5142
GCTGCAGCGCATAGCCCAGCNCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCT
+
"8%+A&<$54;!H374':9*>6"&H56BGAF'4@#A'E<?B/A)-G*E>=3C))43'.6.C5#(?90%1'<H&<C;A,#8>B'?32+D!+H(#A>#B66).";<!&%,5'#;1>*37C@:D/::.'5H&5,8G"3A,<%CHC6.;3@@>-1$?H'4110"/+6F50=>-36'D6
@r5143
TATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTNATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTG
+
$++&+)$+'#!!#*%!)+(&"$"!!++(('(%#+*!'!%!))$("$+$%#!*+)#'$%')+"$&)*!"&(&"&*(%'("(+(%%&++(#()$"""+!""%#(+)"%+!'($**((($&#'&(!+%#()*!"$%#!%($*#*''"#'!%)!+#*(#(#&&)'#&++%""&!!%%'!%%)+"#%+"+'(+!)+**(*((%"!&#%"%"#"+'!&%*$(%#$&)%%*%)%&*"$(**#*)!(
@r5144
NTAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGG
+
0?A/#@5BH5DH--#7A+??2"FE5AB&0F!(BB3?$59G#=,4$A2
@r5145
CCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTNGTTCATGAATATCTGGTTGCCCTG
+
32:/9+2F0**<8.BC,A84*<+:?F2#"+%E?<C46H-@EA'#(91H,C?G2?H%+'"+-1"@'6",?/91E:B1F?%0%%&+6-;@?&,0H&%G7"&=
@r5146
NAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGNA
+
67*B)%D$"#&#47#/):E"?19'7E$B</$4;**%F8-2-<#<$D@:%-><)G+2G1+,HH4?(+*E'74597&!&1+7D1E*B9E6
@r5147
TCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAANTCACTCCCGGGTATATGAAAGAGAC
+
&9E,=:'312?--->4,+=./1D/5?'A0H&HB6$6245"$3<&;,"F7=7CG2==:494&G)?C)?;B=?"$,4+H353+,+'183-C)>,GHC1&4'H92;G/6;4<$%4
@r5148
AGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCGCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGT
+
HE6@.<,A6;.+&&B&<7A7HC#-H08G%GC'2-<.77%0;E"?9G9F>#@'A.*A<D$8=5C(=$%+7)77=8G719A+$&D,&1D/#&#"0#
@r5149
TTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGANTCAGATCCACGGAGGGATCATCAGCA
+
2.=&6*-C)/9F5!07<)'EG8FF-':CC!-B%@>H<).?,3(,)58/H5$DH>4.#,!%>;:H%,>@6<(>D2*0F;A=H8!
@r5150
GCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGNGATAGACTTTCTCCGTGGTGAAGG
+
,>;%.!*@<#F#0/.D$"F+GA47$F'"37-#=G<HD%1F0++9,A#5B$5#(>)'DG!$CH,$4?:-H
@r5151
NANAAANCCCACCGGTTCCGGCGGGCTGTCATAACANTGTGTTACCTG
+
**'*)%%+'!"&!'%(**!+%*(&%)+%*#'#!(%*+%'&**$"()"#
@r5152
CGTAATATCCCAGCGCCGCACCGCTGTCATTAANCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCNTCCGGAACTGT
+
%1:67"(,8=7?H26$*<B?4;"G.!@&=%0D/$>,?,:1&#-B'!:;:1D38H6;:6'-9+,0,/:(8.ACH1?1E='$!H>?5;<D3)!/".F2%*('.>/$,,0*<3#@A?!@
@r5153
AGNTGNNGAANNNCCGNTNGTGCGNNTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGAC
+
)#))&%!&)'")#&$&#)!$(&%)!$(+!!#)%$!%*'!&$+(*&)''!#*"#%++!$$)&"+'+)&"#(*'!''+'()('%!&)*)%+!%*"%&"!)*'
@r5154
GTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGG
+
7#=7DC'E=/1)3D&/+1C$887GFE*95BH'-4#D7;523A039FA4;)H4B&#*@?FAH7G!3>5?'&3)(F)&!B9<-F3@)01:"*:;D3=
@r5155
CGCGGACCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCT
+
(015'2,<1E#B2B*&3@).-&E$1(9B<,,@+8'7=F!;>31C@>D*;?"5;2H,$@+!&=?CC*2!038E(:6;>(-G+E
@r5156
CGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTNTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGNGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCNCGCTGGACTGTT
+
=+6B$B7/5>#52F8-CF;4$G65?/9B-9&E0*."%22:G?'0&$2<(#/C60%79-8/C@!<%>2**)-&A)<;(6;7$G0?GH2;E%"/.0'08>7GB$5)@##);3*)A&964!69AG3<0#3<:1CDF?1E%@;*'"$;5>;8-A31@
@r5157
GGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGC
+
0AC;7:".D*6/?G-E,0-89'FG1'C%H.E%8,&8/.!@2-C;.56DGF!*G?8AFA)>1#7!$<74><'0'<!!9&$<7&>
@r5158
AAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGTAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTAATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACG
+
;'69-"5F>.;&-6.<=*F:C6/63768E/B&A=&>H9)"3CH78)>+?"'$4--6><+C!#;+.F#(((=!F2).,F*E!3+5;8"-)$A>1+H2'DE/?G"H?"*4#E''14@0;<=<2A)(3A@76<9E3--).)HC4"D#!>#*5<0+/H7:,B>&$7;:=H+'C05&@E'(HF0)A4C+"//<)H)*1'@8$")1
@r5159
GGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTA
+
!?4#"<7;,*AAH$'?F@>./H<>H&%21/(F1@'1'3H4/G?=*->)!'+64%6GGE,#)(147A.2%
@r5160
NNGNNTACTNGGTGNTGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCNCCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACT
+
!#%*"%&))""&$**+%$)'!"('%$(#!$%($(*+&*&(#(!"'$()&((%*&(#$)!(+#(*))"#"%+"#$#&&&!!$*$%+$'#"!%*("!(*'&&%%'+"(%
@r5161
ATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATAT
+
;9H2/EG(57*0$;"%62;1B-.H:!3/:A(!=FD)7(>'>A;(98%*18873G?711
@r5162
ATCCCGCGTGGCGTGAAGTGCATCAGTATNCAGCTTCNCCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCT
+
@6@8/>/6;9.686.@2>/?)=;(=9G5;?5>?)8;0F6$@'->$%'CF,8A%8#7HA0A<;!/*)H#0&'4C6F1$<CB49<AE@1'=,C;%84&361.7.-)#*8
@r5163
GTTTTCTAACACGATGTGAATCTTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCG
+
E14";E78!:'D3)=@5'D&58!E#2H@/*6/!4>4E?3-9##',&&%C=$4.7=%7<05%".&5?>?7.9,H9)07:-9GF-A5G'(;"EB$GH)A'(GG:?"0
@r5164
ACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTNGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCG
+
%<!;.CF(8FH@/=/#6'2<@"*%-2F26**G>G!C+?CCBH+$;$#<D:9?)!/+3?=-85A=.1F;,2H;)9#:#&.F5$
@r5165
ANGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAANCTG
+
'$BGH5))?<5DH6'@'!>!;!+$86@G'.C<6F0%:(6,+1AG;0G)+4#BA
@r5166
CAGCCACGCAGACCTTTGATGGTATTGCACANAATATGGCG
+
%/-0.&D<=/)7?)!!*E67.<,E",+0:B&6(E426%2!(
@r5167
ATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGACATTTCAACTCATTGTTTAGGGNTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACNCGCTACTGCGCTGGCCCTGCTTATTACAGGAGGTGCTCAACAGACGTTTA
+
,-0#5:$+<./5&(-2088)!"*&*/)A4(E0C00GBH30*(0+H$15-9>/B*:+&H2;=@;-#;.0C89=B>4?66FA:?%-/BA?0+4!>6.!0!3>D?>328;*#$(+5?6G9@'.758,02=-E?D!<>/FAC+#/4+H*))8.&3#5=##)6-HHEF5?C*+@C./;F=BEB@8*%0B9&'&,(0?GA9E#D/G,%/8C-;".71
@r5168
AGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCTCTTCCCGAACTCGATGTGTTCCGTGGCTGGG
+
A?469$H")HDG0+>+15D&-CG4=(1B)076!,FG5C<<*&990>4-9;-04@#26++>4F.,A728';FE()C"5")A@B+
@r5169
CTTCNTAACATTACGACCGTAACGGGCANTGGCCTGCGTAT
+
!+(DD>:,%-H*4D;#>A-$/)B<2H!+)*2<&7.6=%+3<
@r5170
TCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCANAGATTCAAG
+
3?F="8=?5?E,%8?9=5EF$:%F*!%%,7%#*).?*AG3FB!35!DC
@r5171
ATGAGGCCATCAATAAAACCTATACCCGCCNGAATGGTNCAGAAATGTCGATATCCCGTATCT
+
*6*@?<1<4?=<0#3A+9B#;203:90:F80;&'44%$5.?$7H5+0(61)+-D7:0*=B3$/
@r5172
GCNGCCNNCCGGNGNCTATTTAAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCTGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGG
+
)*!'$(!!&('!"&"%((&&%!()$+$#&!"*+'#"'#'''"$&(&!!$)##)##&##+!%()!#!("+(%&%+&'(#")*$(!%$&('+**#$&*)!*')&#'#)$)#!+(#*!"!#%$%"
@r5173
CCTCNNGTATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCNGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACATGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGCTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCC
+
(!))#"!+##'(%#()&+&*))*#%('*((+&$)$+"((&"!#')!!&&%$%'))&")!(#("()++))(()"'"$&()%&%#$")!(%'"(!$!+*%%+$'&*"+&))*##+!+%(*#+#%*+'%'$(#("*((!%)**+!!!'+%$)&+&!)(''**%*(&%"'$"'%*""")''"(&$$*%!'#"")#$''*""$&&!%
@r5174
TGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAACTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGG
+
G!@15(HHD!76#/>/9&,=;$&15$E.>G'320GD8*;""A$/<)</4D"%$-#02EE83HB9HGG"A6EH*-FA8D%(#$5&C2D!32-7%5>.3B7:?):(!D(0%0D<35??<82!5
@r5175
NGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCG
+
!95H;C>&"??7+E4&:(/21.F>5=A.F%7-<#5)H7;;1=CG>!?9BEDH&%,&6'B39>7BF/7831;4F@>/8-*$0)%9HB!CF>%,AB8*4
@r5176
CAATCAAGGGGAAACCCGCCNGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATC
+
*@C7-'C*C%,(:'8)6:?42=)-0;7&9#5>)>/FG+B<-;510!??07'236;B%49!C>=5.;%$/BF#H;*C(0F+9'@#+B+)
@r5177
TCACCTGNAATGCGTACCTGACCAGACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCCGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGNGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCACCATTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAT
+
'2(-3*H;0<&@!,A;42<,;7=%0-5@1&B+!68G2*;1%=83="-BC5A:E6G,>HA?25#&?GH$G2E8#2:0<<@?#2A+D4*9#/@)GB",-G)F46H+-@!5(BB."!11<682C=6/G);55'3/59BD<@,,:'?D(D&04-9H"8E(?"@-3<>D?7*),$@@A<5!1#;7,C*4$C(.,>B&<07!(<)4'$2,?%:C*,5H@H@90'?-%"B<$25H+>H/;*H55H#$GA$A
@r5178
TGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTNCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTNAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTT
+
#6;D,,94';G?,B')<<:0,1A$#2(@E'B0,3)(,7204>/6,>!F>.E755G!9DC=A.&-&%&FE4<>?<$06(.FC@E<,)$8)'<,;$+6&:<9#?+0'1+@+BC6D%30)D0$@FC?>&06@?4H=H=2&14@E@)8F1(-.0:$9.48(=++"4(,@#C3+<B3)!FD6B3"/BF7C!094/'@FFG-@/&6?<?B!'9B$$5EBAD*C5,4D2-E(5/F<#/00:3E6.1,(4'H>
@r5179
TTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAATGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCAT
+
-E<&7,7,00D$)<C8:891<&D-2E*G5D")?#/A-H7H5$AF-.**&793<+AB##1AD:@;>2C3D>4.4@'GDG14$(';H4)#D$-+$AC-?.-!H4(>1(+#34E%)$F*F7'4616.01-.+7<('F3;#&&(!88.<7$G1:5"($;H5B3113-G/F.&2:E5B';F<8%FAB3->:D7D,HA707,1HC,<%91*(%>7@0B&(4H?4ED0E9+.A';$*(-(:/:&A@9*>
@r5180
GATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACG
+
4F(E;*A/(D.D,=)?2A!ED6;$AHF2<G7&G(%-388+:+94<+<=7F%@2<*'G-9?"H(2@/=3,E;<0#&
@r5181
ATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCG
+
?E7?&EHF$+$E,44G&#H<E!HF/<=7$5'E-.#/!7G@3C)(0G*?,F0G79*
@r5182
GACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATG
+
13F4H(4/>/A6;GB*79B3:@D$8#("7="H(,"5F)AD!;="C&0&6
@r5183
NNGCAAAATAAGACAGCTGAAGATCTCGGCGTATATCAAAGCGCGATCAANAAGGCCATTCATGCAGGCCGAAAGAGTTTNTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAACAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAN
+
("((&(#&!')&%)%&**"%)++))&!&"(!'%*"$+($(!++&+!!)#($!)$$#$%')"('(*"#(*$%!)"%"('(''**#"$#*+"$)+&%(#*%!'!*%&!)(*$"$%!'+(%(*$#+"$%'')%')'$&!('#*#!(!$*!)"*!)++()*!+)&($)(((#")"(*'&+%!&&'+!&!!"&&&$!%)%&''(++&*)*$($&
@r5184
CCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAA
+
:3*@:4G'!:"1?@!;;.%%568@';@>:-&=@G5$C;!9$9
@r5185
CGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATC
+
EBH/C)/3(A25-$98:GD&:>DE3?,-,.$)2DHA#4H#;$2AE;5H3F'27
@r5186
GATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGC
+
G8.46CG;!9=?(791G@5'(./#=3;A38?/#96&+6>)+*F@(,$'5?C)
@r5187
NCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCNGATTACCTGCTGATGATCAACTGGCTTTC
+
"46)D<5))68FH38"(.EC2+C&0;4D3D>$(3%B&!1':/H07%BE/=''7((G7(CG</;B$C?+:./(*?)CG#A3=(%+D'(='&50?7C9-'=>.(&>5+G/.-!6)(+,(4(A5G2,HBD5.,,)67/=1,B(BF'E=CG@2.C(5=.3?7'2H:DF&9"">H,@5(-$2H#
@r5188
TGTCCGGCAGGAAGTTCTTTTTNACGCCGTTTTCCACNTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTATGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACAC
+
+C()9./*&D54E("8HE+<1..(">>CD1C&=:C="B:30&%!3*%/83E9E=;)#02E2+2A(%-+-+1@2C":72)$$&?<B26=#'-A9/>!B.>??(?'#<E%9>?7%<&$?#'621'H501$<4(;$B!F=>'1/&"@/5+!C>/7;&&2(G/4H17?)(#$>+A1,E@'HBE<76/C4D?9G>+F2>1FG!-920%6207.2.(#7A(.B##>33#E$F;:5)!
@r5189
GCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAG
+
7A##3?D)?+35"F-8<387!%(:-+81*.7GD'$A<-#8B-5)=C(
@r5190
GTAAGTCGCATAAAAACCATTCTTCATAATTCNATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGT
+
E:"+1.%C#E0GB?C@F187)497B8:?DB5.H$5"=0(*76%F9589961@3B(50@/>H9H4;F9/&C%#3:"A3'2F"319+:GC441?@4C8"9'5A1D%3H%.5"=.6@+"#(;EE7BD#3C@"F(8HC)(*=12=!;,70<!;(E@+='%=3:!?>H+)-:5;A((:%$3/&;#!.23E;4">->D;<'!;#4--$H-9E$!!&<25*F!?G0731E!9"5;E?0(6H;#
@r5191
CACTCACAACANTGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTNCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGANCCTGTAGCTCCCTGATGATTTTGCTTTTC
+
)*@B6(3E73"0"-4*H(*&%,!!G5&>=H+!&<;$;:4A5->%CG55*H?G'07>5@)=</.2;!4>04$FD##7#@;BG&9D8"-D50"D.+E05#4-F;/:;<#-,>@B99:D92D'>27BEG"B37A,&=).D'7)?"!11:&!/DE!ED*#7(3-4/=F"$'GC.<7*';#C609(*E0?:BEFA?C'*9(5DDHD>=9
@r5192
AGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTG
+
163"D98C);15/0<5E:3)G=+(%=9B%-%"!&+:2B;-?H$HF)(C>(6"4;:#.CE$.A3#
@r5193
GGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGG
+
GBE;H%%F!E1@E'"13/(*9AA$*%)/+E=(8792&)$4FH:?@39>$%*4F&67?C2
@r5194
AGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCCCTGGAGTGCGACAGGTTTGATGACACAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTTATACCATCTANGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAGTTTTGTCCCACTCCCTGC
+
H-.GBEF:"*:1=<!0H<3G(<,<-1AE=9&D9H:.+:3H+1+8*=$C11A1?4'5?F1+48B1/=,!'88=*:0+-'&DF/G6CC<1#$(-*478#CF'*/30&E*H6=7=C!2'G@E<*$FG4HCCEF,G85A-%/>H0*2,D,F395F:>(&&=5115<"$1FG=6:-:*+-;/<'10:D82)1=33:"F2#EBH9B#9@"<!6;C",&",(+2844>+*35&;.-AE3FBHC'E1?A>5A:D%65-E*11:&?00H?2/+'/)&$E=(0D7C<:426;$3;+*:&+7&2!@2D&3<$)&35H'/#;C?;=',C9;6=.2(8D04@H:&#:'G%'2A*%=A+3+)#0A8;+,:DC?"4&1BH;@B20*/*7&?9(:?%?EC$5G;3!DCE$%+=$8'AD4%==;&8!C)290@(C-,>!+!H1+&8"D
@r5195
NAACTGCCGCAGAAACGCATCCAGGTCACCAGTGCAGTGCTTGA
+
&980HE1.*+0'F@**G$59F=-A/,@&+/*?C6?H*87@E?$$
@r5196
AATACTCNACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGG
+
1/7.&*B<,3%++39A#*4%1B8D:*8E.)E$?@+2.=C-($4.?D!.2A9D%
@r5197
TNGCGGTACTGGAGGAGGCGGCCCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGC
+
'%;A9-1"'(D#B,F'*#&8$-5;11/+;'@G%7A@7,282+-$!C9.9:?=!3C-(&/<>)/!*3
@r5198
GGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGACATAAGTCAGATCGNCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCAT
+
G*5(7'9=$,.E.G#=>%H:D=0!+B=)=649>BE7G<52$,H/&57*+*&:$2-G768,@3E"F!0/:,7>?'69"F!=&,5D:<A95"&D3C9>'A)B77F==A.<E:)$:=(FG6A36/=;>6(,,:B*D;173(031-82DHE6C&/@.*9$;5&@:H9/$D+95:'6&56E?1,0?F
@r5199
GGACACNCCTCTCAGCCGGGAAAANGTGCTGACCGGACATGAAAATGACGTGGGATCAGCGCAGCC
+
%$#()*$+))$&$((")!+"('"!$%)+)+%'"#&!)!'"+)(%!*!%&(#+'+%#!%$*$"!*+'
@r5200
AATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCANCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCAC
+
=8G0D<<HG>@/'$)0-,4F?AD7>/C//.&D>.D//#8>.(2G,3/E3)4><,.9H4#$)$9$>,G!AG(,="H3;"8AB;C/=5AEC37*3/!.!!83,H
@r5201
ANAAAATTCTGCCTGGGCGGNNAAAACGTCCGAGACGAATGCCAGGTAATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGC
+
'%+*!*#$"$+$&!"#!%%&$""&&#)$%&&%'(!'"()'++%$$+')')#&(!&"&#*$&'%#$$*")%*+$$+!"#'("%#$%!++*+*#+&#%)'!!+*!*&
@r5202
NACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACNGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCC
+
#)>0"0D.H+F5(3H..:56$2$482)-,,@$#D"$&>*3382&G$71:',7(872?3H2>$:@=CE&50<0$C8*579=71*$/11AH*G0,258C?C69;>DFD.+%C'3;'E?C=85580#30&>@=.1?89+,A,/<0%
@r5203
CACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCTGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGANGGGATTCGGTTATCTTG
+
')%+!$!$)$)$%"++%&&)($((!&#($)!(%+&*!+*"$$*"#!!#'')%#'%&%$%)+$)%%(&*$+!"')*$'!)#(&'%**'#"+&*($%*%%"!&*!#))#"#)*&)&')*
@r5204
ATCCGGTTTCACCACAGAAAGGTCGTTTTNTGGCTGGTCAGAGGATTCGCCAGAATTCTCTG
+
10$*'??!-:G0/G5$=15C".39'.:-5<3=,(E4@'/6<B18H##D$;'>$$(=?@!!?%
@r5205
NTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGTAGGTCCGG
+
!++)690""13%0,4D'$*%.%/1$-$;;4/%:F9/-B)G5HC9B23H*<(G.(B)<=5
@r5206
CACCTGGCNCAACAGCCTGCTCAGGGTCAACGTGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATTGAATTACCTTCAACCTCAAGCCAGAATNCAGAATCACTGGCTTT
+
5@:HG!'60(<#4/2?(G4BC.75:=D2*%=CEDB%+CA*(HA0B>@13F>.D"5*.5"G=4%>#E0#?9><$D96FDFCGDBG<A37$A70:(CD?,F27+3-,8$<+"<'/$1><0AAFF7G!G,-:A
@r5207
TNCGNNCANNCTNTNANTNCCGTTGCATCCGNTACNGNNTNGGNGNNNANNNNANNNGNGCTGNNTGANNNCGNGACNNNANCCNNANGNNNNCNNGGNANGNGTANCNNANCGTNTANNANNNATGNNTNNCANTNACNNAGTNNCANTA
+
"$!"$$#$!"#""#"#$$"#""!$#$!"#$"!$$""$$##!#"#!#!!"$!##"#!""!$#!"$!$$$#!!$#""#$"!"$##!""##$""#!#""$#!!$"!$!"###$$!#"!!#$$!$!#"$#$#!"!$#$!"#"#!!"$###"$!!!
@r5208
TGNAATAATTTTCNCAACCANAGTTNNAATAGTCAACANGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGNATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAG
+
(#!*%!#''(#*&$&%%*($!"'#'!('&+*%*$"(%'$)+$&)('#+$%!*+)''+#''(&%+"+'+&"&)!&*%$)+"+("+(''%%'#&)$%%%%"*%#(*!'++'+')*"+%!*!%#%"(%
@r5209
TACCGACTCAATAAACANGTCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGA
+
,57>!>,"#=%;$6<;6;8)=D4+'>&B0AF;2'H0+:"5?)<;;#71-?45"B)?#%"340&FE(*+A/1DFD'G3(D)>=D%!=5G?9:6%8&"36$9*#(.<!!E7A+5&D=DA$32(98<;%2?G3!%
@r5210
CCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGT
+
8*-8D77F:)<*+!*(F:BC1F?D=5&+=.6;==A)@@3"44.,)#;AC.A0#>H)D'B@.9;#*&1*2,F@/F08+H%!<*)"%4.=%6"):.5@DD-'/#EC."/>;(44="6*C1A>>>)7H#HD:B+%',?
@r5211
TNCGNNGCTTCTGTGGTNAAACCGGANGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAACAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCNAATTTTGCTCGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCC
+
!($)%$$(+'(&*)"('*+%!(!%#%+&%+*%'"!)"%+#'(*%'$!''%('$"(""'&#+!"%*#%%++'#"&$*&'+)&+'"#)$'*(*$"($$+)(#&#*"&(&"'&!&#"&)$(%$(%*+("!$%&"+$#"*)&*!!&)('(%+($+(!($''&&!)$&$++(!!(%()*)#$$+#+&)%"$!)!+#%*&(&(%'#%$"*''#($+&#&(
@r5212
TTCCGCTGGAAAGTNAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGG
+
0(?;AD98@!.+F?B2";".533.=94C##@??;*)%#033:(:DA!@?)/F+7,$D>,B@771.?(:F7*B7=('6E2346&)B<53+:1/1,9*E4
@r5213
NNNTTGTTNTGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAG
+
%"!)&$!('"))+)"*('')%'$&!++)&$'"$$)*)*#)('()!*&(#
@r5214
GNAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTT
+
040"1G1"=>:6F?.,D>+&+A?"&)"CAG!?C)C8&-0/8*.,(G7)&;.99,$EAG+=/+C3+%0!<02$H.;5,F51:*:,7:E.:-H6>$=<)*%D-1*,$;C4+,-=$E&%?7=%#$;@?E;E=!6=#7@!/
@r5215
TGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTG
+
HE:H@>2D1%8="ACH@9)#6*$8D44)D-GA/*D73>D5:#69!(59!%4=GF24B%'(/EC)B,D1@7+'3>%8<6A?2EG((9912:/9>G<B$;)1:=6%&)6BG71$(''5)-%-D820"($-0A13(D9=/.4'972G2*':2-+0?*"B5=08::9.@0.$E(G8D:40A'!!10.%2$&<1*:;C?"-72&49/*@,D&=";
@r5216
AGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATG
+
:52FDE3/';>C$?$761:!+-#G;.?G6E=>,A2=</">)=:;,8?<.C%!FDF0.D2!G5*&C*H*A))#31&:A)!)&(.,;11!C'2?,ECD
@r5217
CCTGCATCAGTTCACCACCTGTTCAAACTCTNCGCTGAACTCAA
+
H7;!'1>C9D7;@*8H//2/#%2<A,1>>A."$2?763D:;BB%
@r5218
TTACACGCAAGAAAAAACCGCCATCAGGCGNCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGNGCTATCTGCGCCCNTATCATCCAGTGGTCGTAGGAGTCGTTGATGTTCTCCGCT
+
E#18/93:13&/0?;6B)-B261GAE$;89@40<8=A<4?7H7?%;.&F!<GAB)!75:(:32)7AB'":(094AA'61H@E1D.AC4$69<GGG<&G3:.>B3!A,C.&C/)F>"3$73%)5>1A9E*-)8E(6
@r5219
ACACGNTGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGT
+
+#$%"!($$)+$#&*'#%!"$+#'$$('+"('()#!#"&%*#$$'$)&%+)&#%)!#'(
@r5220
CCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACNGCGGTGGCAGCGGATTTGGAGGGCAGTGGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTT
+
0.B.2F#7%9*7;1G-&,.70:8*D=6CF'2G53#EF=;,(E#&;>&5@$$.<#.C>5H,8HA:7#>3A-1=G6#-$A;(!H5+&&.'29@$@'376=#+7E-';(+C!C@8+,(AE7#$=<12):
@r5221
TGAAGGCAGGAAGTATGTGGTTACATCANAACAATTCCCATACATTAGTGAGTTNATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTAT
+
'+'()#!(''"*#$(#*&''+$"*#"!&$+'()#'(&'*($(!+!'*"&&)+'$(#""()+)#+#$$+"!#%'%'#(+)#(*!+((%!%*'&)!"!'''#('"&%+(+&+")&&'#*'"*
@r5222
TCAGCAAACTCACCATTACCGGATACAANCGGAATGTTGACCGTGNCTGCAGCAA
+
%A?=71?&(=!1/8281G*%&.B#2,&6=(=.8D@#"D%+$,>$$8!4CF@%+6F
@r5223
AATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCNGGATTAAC
+
H;$B!C'4/?(5A75$#/"G4-!B#9@-F%A$&H-:5?+#"@E57HB9$6)2'.>;"57;?375:G:01#1%<3'5E5++
@r5224
ATGACAGGTAAACGGGTGGNAACAGTACAGAAAGACGGACGAAGGGTGGAGGTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATNACACAGCGACGCAGGGGACCTACAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGA
+
&E%A>!&"6/-?$EC/:(D75G*1)<>F,/7>;(81"7@",,01-F.2A*/1G5.&%%A7.E)9>0@A-=./>;*<C%?$-'.7G#4D?&91.C(E?6#%!)0G=F"/':7)?,97!#@+#=:7E4>:1C#E2&270-85H+:7&*G/D+#!*-9H.+4*2C?DCG(0,!9$"H&$.*3CE8740EE.1>FDF@'1>H
@r5225
GCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTAT
+
,-E!A<",3F/&D%#G;9B>%>7*-%&76?HB8G/F-58>F0-@#H!D.G:?;(;==+45H?4;+;H2E24
@r5226
TTGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGANNGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCA
+
705+F@041<8>9>>G233GG091G"2C0*A:-88&EHC.5,>4964D.5@D%!F-)$DFF50?,"0,981>C?#E99.;/4?9-21(:;36$*?E$5D$9<-)-9H$3.@':+=1H?<9
@r5227
ATTTGCCGTGGTGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCGGGTGCCGTTGTCAGCNGCACAGCCGGGCGATGTGCNGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTG
+
1C,:;;&3#7!C3(,7#G/EE/!37$6;G(3,%8,"+C*">:#"47C"2F<&&*'61BD;73+3#/..6D"00<-!,183/8HB')+"9D/57:;<36D5'/C4>=8!F8H5:>-#@7')<,"*HF9=C5-3DF>!5.A3'0)1)2-=':#@6:>/'-'/0CC8=@,<$6+E.1=%,,*>%8H-A=4;C0F!/(<!%;%!7:CA.0HE1"H2C&1'.0&H4,;+:-#CG1;5?*;1;09:4+>#B;#--G=/<&-F5D?+6#-,=%>0'?H+-,F$89"8;AG,!D#2!33-/*&#H2'<->1.*.4%A$@@*-B/)5%(($)<C2H3?C,(!;!77@7-@<;+D
@r5228
CCAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGA
+
*+("&#$(!&%'()#+$&*))!'$)'"&+(('"!!$($*!!+'$'#$)'("&*&!)#('+&()#*++
@r5229
GACCNATTNAACGNNNNGGTCTGCNTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAG
+
!&*(%)()')""*$!$!++$)!*!!)$*%+&&"$')#'!$+!'++'"#$'('"$''!#%*%+!$**#!("*%!''(!(!%%(*&('*(($#%&("+*%'!)'%$*))&(()'%&))(+*"*!
@r5230
TNTNTCNNANCGGNTATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCGGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCANTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAG
+
#'*$#$*)&#))#*+#+"()&)&$'!'!""$"#($+$(%)+"!!)(%$'#*$%++'#%!+&)%(#!$%")(#%#""#"**(#(*"#'!%"+")++(&$'#$!+*!%##%#%*$!"+%&*!!"'%%(*+*'$%&&)#&*#'&(+!'!&+%'+!+"&$&(!'*&##"*&$#
@r5231
GGNNCTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCG
+
'%)(%"(*'++%*"&'!+##!"(&*#+#!(!$")!$'%#%'&$'&*%
@r5232
TCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCC
+
9+.GCH=$G!0*%%*)$A1!8H/5?$)./08&36/5G6+A$C=77!0)A04;-%'@%6#F8.>#!AD+,>>H$6:-B>'!E?3.##+?@*,
@r5233
TNAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACA
+
4<@);55(36B+2(@+))">@..&;E4"*)EH"3(-;%5E:D(?@#'C-D2$;.$,;A91F6G5&"1G;3-G8@#@:'C2<:5AH#117"?H';#HB$14+028&"E269(??97;4A'<&)9,;&+7EG868C):C=7@951@-0**7*6B/D&DD:;'C0'-<G.;
@r5234
GNCGNNGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTCCTGCTTTTGNTGATGATATAGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAG
+
("&$("+!")%*"(%#$%""%+(*"#&+(*+"!""($$"+'(#&#'((*+!"$#)*+))+(&(#"!#)+#)&&))"%+)!#('#'(+(*+&!*''%&#(!#&*+"&#$%&#*$**'#'!%*+)*)%*+!!)+#($(#)*$+(%')#)'+'"+)&"%)"('*(!#(&*+*+&$&)!&!()*!&$*%"($&)&+('&))+!$(%#%*&")'#)%*&+((&*#!+$)*!
@r5235
ATTATTACATGCCTTAGCTATAATCNATGNCAGAATGTATAACTGCTGTAACTCTCTTGNCCTACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACNTAAATTAAAAGATTANTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTANTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAA
+
5C-E$=0'$$/.AH(9<"5&&#4>AC7=E?5378B*!;B;2>+.'49E'"=@(0)17H9!@.@;''1A#*2G'B,C?>>27E2'F6F.F<HEC+6B8-:B@';(H.#>#$E7F5BE,>%6&2&F&/B&34GE+?<9G:GF,E$G;G+E:1><6*!8&+B,AHG%15B;'#5)!42/9-1$H4:(<.C+<7%F36;!-?CB'1B@".+GG!G76D*D$59'H)-D-+87=C#.,2"'E@:%)CHB;!G'*-)B2ED:&06'!,3<7B9#)(25=F842.-69%-DF:0"+"-9(1;G?<96E)D<5"2<7<9)=#F)H2;&2<.$")=D=8
@r5236
TNACNGCGGATATGTTGGTATTCCCCTCAGTGTCCAGNACCGGCGTACTGTTCAGCAGCACGCTTTTT
+
$$&"$"+*#'**$!$+*%'+&("!%%'*!&+%('')$""#)+'%!#$!%&'''(%'++(*#)#!(#*&
@r5237
GCTTGGAATGACTATTCCNTTGTTACAATGTNTTATCTTACTGTCT
+
&+C5F//8&>C(A238B-=*1,7+A@D<"+C7D7-;:*<0&$&"G0
@r5238
ATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATAC
+
FH840>;GF42&B#1D"",,!@*>30HGE5-H="2B%).DF!%15)1:'/7;025B+F:6A3*6%H.C@'E
@r5239
CACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGGCATTACAAAN
+
#/CD',!?,B,><1%2#@/?#>"5;*:H>(5@C<GE22!*("1E?A@$1%EB39(+5FD-5(G5B1+4;>-?F+G
@r5240
TCNGGACGATTAAGNTCCNGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGT
+
(%!*%&)))#$((#")%("*+*++&#$"%$*$("%#$#$(+&&()((+*#'"$*&&&)(&&"+%!&&$&"")*##%*#$%!#*!"$$&#'("()!#)'$*')'#)+#
@r5241
ATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTNCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCAC
+
19H@9831C"=81G6'CC4)-)>A(-71<"#)*:=F#14+36B$$9>H)"8,(C?;@%-FD/)B&/6+$4FE;HA+<B9H)!9
@r5242
NTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTT
+
!3'=*35=0:5H>E*HE'E*A:B82037<@A@F8")HD"H>8A)8184
@r5243
NTGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGAC
+
%EHDH=DAFBG-.!151<B8*!1F7#*='8%1C:0A:)(C$$)9!;@4(4'867G"&HFE(=
@r5244
CCTTCGGTGTNCAGGCNCTGGTGGAAACCACCTCAATGTGTGACAGGAATCCGTNGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACG
+
#$*()+''%#%#%$*!&$)#"!*###*")")&!!%&!*)#%'%#"$"$("%)(&#%)$##'(&!)'!%$&)""(++$&+!($)"'%#""(*(%'%*##%("'%%
@r5245
CCNANAAGCCAGTGATTCTGCNTTCTNGCTTGAGGTTGAAGNTAATTCCATGACCGCACCAACAGGCTCCA
+
'&((%*+%(#(%+#!&+++!#*!"(%((!&('%!%!$#()&"&$)!'#$'+()(("#+%!+&%&+)!&!%&
@r5246
CAGCCTTTCCCGCTGCNCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGT
+
7BC?"<B%$C=!">0"9&)A/H72$4>GHG?4D-0@.'6DG'@68G&8*D@'0'(>=.HA
@r5247
NCTTCTANTNNTACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATCCTACTCGCTACTGCGCTGGCCCTGCTTA
+
$'&%*'&""##%*'+'"%)"!)*)$"+"$"(+))##$('*+$%#)'$&*%++%)#%"$$""))+"'+#+"$&)&+')##(#!&!!+(!$$*
@r5248
CGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGNATCNCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGNATTATCGCCCGTCTGCAACAGNCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCC
+
?&)8(.&25+-%!</)&+G'4C#E*F&H.E7&/1$7=;A31A%$'762;)C;AB%@?:B:DF(;F:4&3:%"%)39$F7-5-;-1</436'$B=,'/:8";&<D1;=-<0G-92%B:'4GEG:F?3(&98)3&618A0-,H?8'80GC,$%=&+&&+7'6$887(01D88F+%DD>.=1;$&C';0H5.$0A0B<;;9::H8&/+1B"
@r5249
ACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCG
+
.?$;:=&EC%@&@29#5G*(FF%(E86+A3?CE6/HG6FGC%5!4866%+"+0HA@19>+5&;A>:?3(,',)9$'7?1%5,@%-FCFC19.
@r5250
AATGGAAAGCAGCAAATCCCCTGTTGGTNGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACA
+
;)")F81D,<5!="+##+7&=4<A*5&C!6*,=#)%#:(E3.*@>-(=E'G'D>8E8.E*)'6+$$'.;(,4;BB'=B52+%"C2)4BE%(*6C!G?&4%/D=)9?C<H(D3;"C7>=**=#5982FA>(22;%D,CD/#1**49>3<
@r5251
NTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCG
+
#=+.F,##<A!709'C%B#!@#,>.9?5,F3%/$5;(5@7&,,#3D'/D6)
@r5252
ANGCAGCGTGAAGCTGGNATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAAAGTCTGAAAGCGGATTCGCGTAAGGGTC
+
!'!%$&+&$'&+)"#$"(!!$%'!&!!!*&'%$+*")'(**$'#*(($!$&%%*'&%&!*&%'((#'(%')$#'%"%*'!""+!('+)))""&)*$(!!+'&"!#%+%$&*&'+('$!(%'&&)!&)$)*"$&&*)*"%*"!"&*'*'))+")&!!*"*"*&""&")!#&+"$&'#("*##$"
@r5253
CTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCGTACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGNGTTGCCCTGNTACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATC
+
3?;+?&<$G*7";3526D.G53C/8/(H/$B?&G665<?>8*/G&6/&/%-(?'%AC3E.=06?8>A>&-G6C(9@.H".@;.@"*FF"7(/<-&H>!+<"5947B#'5;@*=;A3@%#FC</<;1&H1%6G/8C.?1&3+@4""E2(@(@#78:C-&8<!6;=+*)+(8D+.EA02-8';=G0(4232H734"36C5"&7-><
@r5254
TCAAAGAAGCGGGCGGAACGGTCAGATAGATTGATGTATGAGCAGAGTCACCGCNATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCT
+
HB%!$H$':C6<-B+FF*4A5,>DH&544(-C!A-2C8*E79"$63"E3*:+6;8--'D=&FF#.'E6/,#@6%.5%33;?'=CE:A.DB6>5334/3-6;>0
@r5255
TTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTC
+
H##$FA:%<0G(>);;G0+A71/2/(!/'-B@8/394'!(,
@r5256
NCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGNAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCNCTGCACTGGTGACCTGGAAGAGTTTCTGCGG
+
%,2+9E1<4D6HC1**'47/-/6A2))"!+#5-BF&$.-2@-:68,!$2A?24+."1>':8.*+)%5?("E9?'(2)HHHH'C>F(;C8A"73E@&3()*"D8)E6+A(#23)G,*A
@r5257
ATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCG
+
40#@BD25)%D!4H)/@;1*9B?*@4A#0!,*/(/A0B'@(1->=#.7HE*/3(1D@=H*#&85@,5C.,.&%C6C)2/'4)+$-G;
@r5258
TGNTGNGANGNNCGTTTTCCTGCTGANGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATG
+
)'!!)&&*#'(!(&&&%'&%+*'!#)!"%+%&""*!&(%%")*()*'%&&*()(+*+**#"!((*"#($'')*)$#
@r5259
TCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGCCGTNTGGCGAGACAGCGACGAAGTATCACNGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACNCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTGGTGCGAGGAAAACAAGNTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCT
+
D0)7$%'0HA?<;A)G8;4A*4;4!@EFF'62@&5=FD>4!):,H#E(2(#'<F=3&->2@CA>183B42D(2B$.+G>EG%-G</<09E@?+;&!&4.,7$5(>8"!+1:*!5:%A7>B+:<8:D,%H65"831?$#9F'H=*H)+?#C.+1E>+8E,+>H4%.'DGA/-'<C</"<%E-B>+?/:;+45;%4)BG8D>$%662*:?*8EBBC-+C4!9!,!F,F1&+<$C">&B!2*=@3=D@8D$(0%6!BC$=?092>-1%$;0%6$5,)H5B?*2D@95&C?*&"4DFF+-&50-<???B;C5F*'7&>.4&F1??)(7C*,0-D*/C,A%2>$/G)#A#<F"C6/2!5#12!8/"-,*CB3(E#!E7AG-21F-</:C#G(+"?-
@r5260
AAANNCATANCTCCTCATATAAAAANTATTCGTTCACTTCCGATACGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCNAATAA
+
##)"$(*"""%+'(#%))"**'')(#"*+&&$$(!+#'"+)(*"#&()(#&("#"&&*'&!("!!+'$'!!+#%%&*#++!$$&*#'#+'$%*$%!((&*)(*'%#"#))'$*)&#$&'%#%(*#*(*$(!#"!(+$+$#
@r5261
NGGTANNGNNNAAGTTTTNNGNANCNNNGCNNANCNGNGNCNNNNNNNANANGNNNAATNNNTGTCANNACAGANGNCANNNCTNNNAAC
+
"#!"#!!$"!#$$!#!$!!""!"!#$"$!#!"""$##$#""$"!"$"!$!#$$""#$!#!"!#""!""!"!$"###!"$#!!#!""!##$
@r5262
CCGGAACATCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGNTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGA
+
15F)/7>#("&7:%*#><'.8+FB!*48"D6(7?:2993&'/-="'7B@)'1*$G73586?,2(CFE1A"@@DB0#(@.38!(,%+(17+6?/G%6D%8'0-'4&<%G4AB8C982"0B98<08%A3,
@r5263
NNAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTNAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTNAAATTA
+
#(B><9)1-E<7A-B=<D7:8(.F8D:2G>0A7,1'3?A;+'>+C6(18'>:3<#28?@98@?5H2>A+..(D82;&+!E2)E<9EAH@0AD&%(6C>8/6/488==<B@1E.$2?BB2(0E?G"""&=6?=,F=:!*5'9>.
@r5264
CCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCA
+
+'F48:(-"9#<B-0'-,)A'-A>+6!HA?4?EE85H<"(G*:4)232-/9@""/"+<HB9"()#**E'2!*8%+
@r5265
GACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATACAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAA
+
7@%.',?$=5."4=?:/=#(:B#AF">4$@5C5%B)?358,A#-(H5'%":=>3<$)H:&28:4C'?H4!*A6+";8.#(4::$?9E2(,G.97:0,&28-.A2<-7H%(8<;0#;DC#':
@r5266
AGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGNTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCANCTCGCAGTATCTGGCCTCG
+
?H7(+*$4-3-556:>F/330-64A+-;.D=&'?8!E%/8'1F@?B-$+#G9F6D.*!/GH?*=30<%4:97+-7<1G3&992'!;69:/HH>0C*6#8.BB.=2FBG(/*4"&+.C&1$)4+G'"69;.;<+C$7#;(809#%.(7.214D8,6"9/D:2"<C,4#8&8F%,.$9D8A(+(:8$94*?$G%-6&.&)%:9!C:+=?+2H<,;*")<EH;(2?%(.EF=.G<4;F.=$+7'@+B2G1=;#"-D->C6@E<(9$+?D(488#:4=6>G
@r5267
GCCGACGTTATTGCGGAACTTACTACCGCTCAGGCATTTGCT
+
7,)H)FH++5F7-88<6B*7C-*4E%03B5&!5H?A*H7$<E
@r5268
ATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCACGAGAGTTACAGCAG
+
/D&14<<$2H5=<=9('H0+<8-&580B:/(4A@G1:B0/>$629,5)7A<-?3
@r5269
GTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCNGCAGGT
+
*C:$>&B4,!%H*.'"82&C000,H?"@43?/>C4(&!?/:033)"#=G7+,1+:A-B2FA2C%#4H.AF1?70.28=&&4*-/D&6AB((3&
@r5270
GGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCC
+
E-?*D<",F!EB0+?2-58,57;,$/.>4-''8#$E8+=:/*G2B.$>!>
@r5271
GAGATGCCGGACTTTCATCGTTAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGA
+
./5.#3+$(:F@7(>9)1$"01B0.<5<6B>0,!D-D0F9!!/)A4(',+BB'1!/5&1#4%9*%A#(1?+?$>D+
@r5272
TATCCGGTGATGAGCGATATCCCGGCACTGGCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTNCCGGCGCGACGATGATGCGGGCT
+
(+)'$)(&"##$#!!)'%+)('&$)%&(')!%!+%&$(*'#&+$"'%!'+*"(%*&)(*)$$%#%#!'$"#")!($!)+%+*%&""'+&+"$'$
@r5273
AANCTNAANAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCCAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAAACAGGATTGC
+
*'"*)!')&*+**&*$&)')'+$#(+""+%*'#)"%)'%$%#()#)'!#"+$&(!!#'*#+)#%%"+'"'(''*"""&#%++$"''))#+%+**!%(&"&$"$&&)**"%"+#%#%+)("!&)
@r5274
NAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAANTACTTAGATGGTATTAGT
+
"&54?)H7"30+D5;@BF%8=B&!&+;G+#BE1!;A&!4==5*;6:>!?G+F:@#2-A!.5/'D?C9557/%
@r5275
CAGCAAATACCGAAATATTTGGGNAGTTGGCGATCTGCACGGATGCTACACGAACCTNATGAACAAATTGGATACGATTGGATTCGACAACAAAAAAGACCTGCT
+
AD/E/'ECC/D@G")9;A&#8.CH+;+)?-!&*A3&./74$&$AD7A7*DDE39%2=-@.>4#/!D)329',H<%=9">C;E!''@)*&D6:'/E9E,'$E,?88
@r5276
TGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTAT
+
0"!.)(,H,DC2<<#>2':H@19->@>*,9B=&=3*B!BA?#DB@3D2><&'+H-+B!>D?">;;,>9C@7$=%!1?/%,$8")D/3BC
@r5277
NGAGTTGCGCAGTTTATCTGCAAGACTCTATGAGAAGCAGATAAG
+
"*-"?%4&&9';E><,2"==0A+<@%2-+:$?+*8+?D"&@4DAE
@r5278
TGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATNCTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGNCAGACCANATTGAAACGATAAAAACG
+
.06(34#5.>*4)F;,:93H"FFE;.*D)@#3%@:8$<A*&%:H&*B@'3&$?+?@+G*85<11'71,*%F$1:4"!#HA2=*08+&'&>D8,")2&;@.6C!!8'G6<G@2/2A,D:B2+(02;?9B<77CB&A(<,B58D:.A0.-;A"-D8E&)-;?
@r5279
TTNTNGNCNGGCNANTCCNTNANNNNTTNCNNNNTNCACNANGAGTANNCCNTAATNCC
+
$$!!##$!!$$#"#"!!$"$$$"$#"$$!!"""!#$!$#!$##!$$$""$$"$""$$"$
@r5280
ACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAG
+
>1$A,A8$(('&/*,"C9&H5>%'1/13A.HC&F!1028A*.AGF(B!,5C"-+*:BH#!'!!0EHC:
@r5281
CTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACNGCGTTTAAACAAAATATTGAGCGGATACCGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGC
+
G&D2><9E-2>)!@;AA)*@=4D0;983'1(A?54&4H2>%<G5=,6D"=;25@)HE$)GD32F<@7?6:?4B88H3@8-D1HB$=/H*==-+4>2*A/F<?G<10#(4=4A)<>F2=7B?#)><=--*%:'7>:B*?D8>F*;'F1E?D*:!1+5?;9$E&;#)7$B+%&235.9@&H&$:2,>7=G4G(E9722AF)''!/:?G#)
@r5282
CCTGATTGCAAAAGTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACANAGCCCAGCGCGACAAAAATGCC
+
'3D+-E''D,"#*,>*7D--+D=7A?='<:99#88!&9E1..>7&@4@7,;!-@>AC8*-&F6#&#:$'0'-'>$GA@2G>C05'CA=).,365$.4=;$&#$HC80&!4?!#C%=1G3,3.C760#-3G:'!:<*0'E=?C''2#-9?G9E9)DD"="'6:B5(A9/-:7,F#
@r5283
TGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATC
+
&>F$0,.B41F7E>/0-F;G!F?9E3B8=A7"("@4#-:8-;2B:$B%
@r5284
CNTCCGAAACTGNGCGNNGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTNGGGNCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGNATGGTGCGCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCG
+
&!%("'*$($)$#'*()(+)"#($*&#'+$!%$"$$**#$!##%#"'*"$$**#%#&"!($&'($"$()(*$&))')$)$*+*&+)*($"#&#+$)"#&!"+&'#*+"$'(!%'%%$*)*+)!*#(!+++'(*+#"+#!($$&'&$%&$+)#%%%*#"*'((**($)*&%(&'!"*+*!#)&)(%"$*!$$!#!"!!+!(!%'('(&+(#$+++++'$&+**%$&%()")''%%%!!'!%)$%$&!!*$(%+$*)"&)(#(*("(!)&)!)*")&*$%#"*!&$"#"#"$(&+*%'*""#+#"*'#'%$%!)&))"(''(+!'%&%(*&%#"%
@r5285
CCGCAGNATATCGCGNTGTAANGANGNNATTCCNNANNCGTACCCAACC
+
!**('$"#')'%)$!&&*&()!%)#%$!)$$&&"!'!$*")#'++((('
@r5286
NTTTTGCAATCAGGCTGTCAGCCTTATGCTCNAACTGACCATAACCAGCGCCCG
+
'1C:)+>?4/D0?'%F6:%?3E<AF=>H5(2/)AH")0B#/44.G-56>!)5>G
@r5287
AGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATC
+
2H#%87@DE0A8-9#.HF;38G,,F$"$&:A>,-97G>>')"1/1>8A.62399..C,+)27C#%&>6/$-6
@r5288
ATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTNNATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGANGGTATTAGTGACCTGTNACAGAGCATTAGCGCAAGGTGNTTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCAC
+
,,>H>.)*D=CD-)EGA78:".;2A8A,%=.H*=B4A7@0C-;*<.H"A'/E(B;9DB,:6=G"!2BE:,G><%/<,A+%F#8+5($7$F-:09G+(3A08=DE4?D4+=92;36&&;B2%9G3)7"E(!&1F2=60?!777#86$$*G819=)(A65G6=?%9E95@GB*>+F.?0DA1B*'8;5:1#)A#9)3G2H!E?%,@)>%5688+<;1%6"123;AG?&7B+;G!4(>"G/+8(!#>.@0F&%1AB-
@r5289
NNGTTCCACACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCC
+
%+%$&+"&!(%)#!+)(+!(%'"!$&#&)*)+#!$)+"*##*'')#$#"($('!#$%""&#!""&(!*'$&
@r5290
TTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCANGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTT
+
.*>61C&=+@5?H841E"@DB#3>?C;:2E4/#D<"&B-087E*A#G01D4<%88?<!5"!;$/E5F).43<4D6-?7=>10%8)5$;/D$</6<5=-;>5%93B;C-8>:@4"$$,!ED;GA77B*&B)F22(E,9;#0<73.=F1C80"'H=G3B;,CE/#=$9;:*3EF<'@$D93B"'2&3:;/!3:?5BH:"78B,%%04?7-!#*0:#B-!'.96@C4492HHH>.
@r5291
CGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATNTANTCGTCGCGAACCGCNTTCATCCGGCACAGT
+
:C%2#:43C'7?G12(/>%249A>-&;H<%*FFH&@:5--:E:9'3/9);E0.;6C+EG!2/A>;F;2(9#(?;3&#9&:>9B32,&7D3)$ECA>3@/3D8
@r5292
NTGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAA
+
)470B&8H'=B!#A#886B/%%"E@&856BA9%>3;F&:"21-7>'3;5(*(8":*4';F+F5)<H#$$=7A:;9#0D>$G&$8H9(+(+$/>=8+5E@69
@r5293
TGCAGGCAAGGTCNACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTATCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGC
+
C.#3-709=4-781*GA2B0)5GHB</$,#6;&8%-."F*';.B-;"%"AB/'A@3>A"5$CA8FC<80G6,&',=C8H4'6#:7<&#;&$CD4$.A,:D3'85:<'1+!13G;+*99C7;<&618%#F,'<-2>6+*A)')C"&8537/)D!?0CE6!?.6
@r5294
AGCGGTGANGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATG
+
17;.D"!E>&>$$)*'@.7AE,0#!%>;!2->0<.-:#9&!$4)91>/148%'6?/@0;D@E-%37&$*;#<51$8./?5H*,$%C0*0':
@r5295
GCATCNGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCNCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCNTCAAGCTCCTCTTTCAG
+
?@C7@F>@&C;D'A:D/-#A4F?4"#+"*%?2>;$92$8%.%A?)/+!EG%+2))*,$,5&;9C+A2,E,*+#<=$F#3$2;0,,CC'C-@97/)E##3"#/6!"E85F+H+B$=@!5CC&H5BF"DBBC->.*!DA>,9#=E)=,<=.GA0E4*></$!+69'?36G)335H?%6
@r5296
NGAGATGCGGTGGNCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGT
+
"23D@53,>56)"F,E'@(,D6E/B0A5C**1=56=;&&)7,>.E:08-)#=>%><2CF%
@r5297
TTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCNGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAG
+
!H7F=2$)=-<+G&7>>E%C%59F&:G!<ED;9B43=C+8*"5*(DG*65#048"/C@;-?4A"D<AFE/73/8&#.C-54%7H#C.;H@-2?C';A3D+.0'*H*2E*89@G&'<H!,.'2C!89G(:'2G%#8;A3="HF?G
@r5298
GCGTNACCTGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTAC
+
*%$)!#*'$$+)$'&')(*)()''$!"(!*%+&+&"$&")'!!$&&)&"()''%&($#!#%'%)"+")*)#+%'*!))#+$#+""!')%("%$""%)!)+*)(%('"#&$*%&+)!'%'('!(!+"#%"!!!#)$&#+"&)*"%*$*##'+'!%)$+"'$
@r5299
NCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCNTGGCCCGNGNTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGA
+
#8%<=<E++?>C9936,-6,.29+D-7B4D36(E211;!'<*<$/!;4G*7)(755)&%35*/##05>>H)C!3&E1F,*12<?E$&@%>48#C7/E=?B
@r5300
NAAGGAACACGGCTNACTTTNACCTTCACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGCTGACCGGATT
+
!%&"$*'')$()(&''&"%#"+)#+'$'(''"+$+$+")*&#$')!$$!*&#!""+*#!''($#*&)(&&#'()'
@r5301
TATTTATTTCTGAACTCGGTCCGTTACCGGANAATTTTACCTGGTTANCGCCGGGAGGGGAATATCAGAAGTGG
+
3AG;*=)=*F>3"3;!475B!<G3.9BE.0&6G<!E$*0B)H)F708,;<:/F4$2&G@@>E6)()5>=>(4:5
@r5302
ATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCG
+
7/:F-G%9EH<%("=,.AGC.=!9$GH,<+"0,("!B84A"?)C@>?'"0G)$$)D:;$,;3$5.A-H$H;%61B$48?,!,-0(":D851EE1,CA5+%<394#/#B(300C*4D%=8C4*9C=6!A3E."+(+%D%#?6#)HF))4/7A4$;(>GEE.&6(2>2%%2'B$B3##@="=$36!1B7%GHBG;6:BC-B!D0H+'&"?-
@r5303
CCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCG
+
.E?@&""9(E&8:72C3#3EB.'E*!(9G9#8F$%"%$(+!#D3+;%B%?;C*>+>=+>B;H8;>$"#FG*):>A>(8?@>>B&'-342@57=&1$7?
@r5304
NGNCAGNGACGGTAATTTCTGCAACCGCAGCAAACTCACCGTT
+
%'"**'!+!*'%*+%#%!)'''!)$!)$'$"+!+"()$($"!%
@r5305
AANNACATGACCTGTTGGCCGCCATTCTCGCGCCAAACNAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAANCAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCT
+
)*)#(+(&&$!*!(*'+!($)$"+&(+#!*&%)$##%"#''#%!)"*'(*&'$"'$*$!$"*'&##*%')"&($$))&*+&(#&++$"''#!!($(!#)($#%!$)+)"!#%+$%#('%#""*')(+)*(#")'$##+)"($$!+!$""&)*!+)%+)+!%$'$'%'($$$%
@r5306
NNCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGG
+
()D63>/*>+?C7!<>8:=FBH64%A10F/()&$4%?5<2#*0$42;B?/ADG@+E8!?D)*D6130
@r5307
GTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTNTGAATT
+
.<!)$>()1*F=<H0&@5@0)&*9D8'-4(3F*1,<!694+>
@r5308
TGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTG
+
+%*%$$&!%+%&"!("'+*"*&"#"+%+*!&$$%$"+(*"'#**+
@r5309
NAGTTNNACATTTCCGATATCGCATTNTTCACCATGCTCATCAAAGACAGTAAGAT
+
%'####"%"(+%$#'%''((#&')+%%(%%))+(+!!*#*)"+$+#!*(*%%")*&
@r5310
TTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCNTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTT
+
/*)/(+"9>E=07=AD8@H;CD313#<,&;?/5F469D(<*8).)%!?>1?$8EH?,F18.'5?<@CE.?#DD*&D1:$1..=/E?<;?D?8*59A*93A2E/F849219H*D4&'A.$+-.6$4-@';;2B'7.263@<=/.32F;&44"!@6=2(1')#>:98G3*?1-&E@3<7-DB+3:9?*$D#9!#G6+CC+%)A?<3<113=)E&>
@r5311
AGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTG
+
-H'G;+'?30?D8<4,5;(%/@<B.<8D=6?4)7060+"#HD9#>BD:(=0$H&,?'903GEE?E@;@(;$E'"
@r5312
CCACGGNTTCAANAACATGAATGAACNAGGCGCGCCCGCCGGGTAACTCACGGGGTNTCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAA
+
)@"G*%(@7+";5B@"F&%2B<EB3*-GD#BH-3&'#)1(0.62B<F&;#)4.*E0$$-EG96-;6@!H+:$FE&C&:-6D*-!*4>9A-H;@!B712?,<,><C4%;8+
@r5313
TTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAG
+
20DE9'>:8**)E-&7,4::@))-#>:5=;#*4FC>(D03>BAF"9(/D6<!G9G-<&#(<C<:.5-;18*)/E!//,H,6051*%:;;F*.D%%$,:5$<
@r5314
ACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGNGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGC
+
8"0?7G8D!E3DA!?&+,F@7.@*!";'7&%#F):(4H7,2,:B)-;5!/$+FF,<;(/4+*2FA/)<1#"'4</>;'@ED):#+*+1#8&!$FH)C(C+)3'G@1<1@.5=4HD%9;$!9*+,0AC05A=
@r5315
TTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGG
+
<CF15F>3')(;'A21)C/;&E1937/'5%#,$=$<10''277)"<?C$ED5'0:
@r5316
CTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCC
+
/"D!=1%>"%$A#<+B;A<?=#6A$'69<3(0F#@>"<<60D#>FG2>?9>C0"?=9:,%?B""F9%&(.7;(01&%0!E"%%?
@r5317
NTGANGGNANNGTNCAATGNNAAAACTACCTCTTCCAGCGCGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATG
+
"*)(&(&#*%!(*#&)$"'"+"#$)*$#!*(''*#!()''!'$)""&!*!#)(%&+*'(+*&$!#!'!!))&'!+')(+(&&
@r5318
TAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGT
+
5C?7!>1?H/C?A,"3)'->45-66-!B/!;E=0,9*,55DG;<BD%E-*+F;-?F8+220
@r5319
GCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTAG
+
3A5'$(C2>%;;4?>8.*>D9C'>5>5=G&5D5:/$2,(9F'A0/F)-36*;!?$-;,F)'"B"HG?!
@r5320
NGGCGANANGNCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTTACTCGGTGGGTTCCACGACCGCAA
+
$)*&)!$%###&+"&"!+'"*"&'&)*)$*%)+*$+#'+$))(%')!*"'()*)&)))")*!#*+&"%#%"(%#)&##&"'*+"%+'*&#&+!(!%*%%&)('!(*%"*%"+
@r5321
GTTTACGAAGGTTTTACGTTTTCCCGTAACCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAG
+
E":!5A@@0?*-5-B:7#:GE40+6,%CE>=/(:..%)!,C."F=5CB!F(8(!=@!46#H*-"G3&7%:
@r5322
CTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATC
+
)&A<0$188C%(1.-?94+"CE>8&$D.C%+69(;0D$85.?#A834H+,*HB8.C=0)&GB!)/<F&+:"?;B8E!:5&?2%?/?F)$C4#B.$C5(;>6'G="!G5#BB'+60,F;9@@!50>:%3%>/;C*#&==C%&$21!7.
@r5323
AATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAAC
+
?'+@-=+%H49,+@:@--1B+;;5FH=%<)")%(;0$&":
@r5324
TANNGGATCGANAACGATGATATTCACCACACCGCTGGCGTTCAGCGCGAAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGGTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCT
+
#"!$)*(%*&'#"**++$!!&"!$%!)&*!#''#$)#**(*$!"('%&'*!+$"($$$'$"()$#'+)%(+"")$%$)%''#+"%)&&%!!(!#'$)%!'%'#$%+!'(($"!&%&')!+$')++!*!%%!#(&
@r5325
AAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATC
+
6<5&?%42;2;3",<D<B970)G%&)5&##$8FE2C%%5$G!(06(G%8
@r5326
CTTGGCTCTGCTAACACGTTGCTCATAGGAGANATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCT
+
4"C8F;;02&%49G8)D31E:2>?F;!582<9::.&2C+*662;*8$>FG;?=?7(!75C92>7F1>.:@(/4.(?3@
@r5327
CTTTTAAAACGGTTCGACCTTCTAACCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGA
+
"3$.3547H@5H/87=,;=6;A;=#F<A.1-3'/E@D&)'E73$G/"#<6.3.7A78B'-F73:D25>,,,<('%)=<2A!+0B.C3><+4#3GC1<$699#588:0A-G&8#6EF)"%.;%73<C,%-03%25+G5H8)*45+%
@r5328
NACAGCANTACGTNATCCTCCGTCATGTCCGCCCCATCCNGGGT
+
""$)'*&!+!!*'#&')!$'!#$%&"&!*"#*'+"((#'!!'++
@r5329
NCTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGNGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATA
+
!C6G7#6F&C0,67H#;>(2*5ECE=>?@+=$8)*%'+6.4H90)%;?D#<).D2%HG@4?9/4"%G4!*&<*!<0(@FAC1B3HB:.,%-*:%6E'61#A?-A,F9%/A*?&=?:!?&.387),/-8$;G@$:"/6?*5<*C%=$@"-C/F()E>GF5@2.2")C3:(E(F0.9FEAF??D%:#5#!,:H.3>$)?H/(F!$8%+%(+D'&35923%96(AFH3
@r5330
TTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCNACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAA
+
-+?,(&-D@6<(H'')!:?)C>H9*06A4+C.F;2+A<H%F)B7HC,4!:/.<*.5:4?3'82;%2#"'#)=A>9-H+AC<14.5F84F;2&&C"FG30A180?)<D*5!+:>7A%<FD'=A
@r5331
ATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATAGTCCACCTCCGGAGAACA
+
-:)A-&3E)'8D9*9+CE?E#D?!@4/:>=8)%)C;%7$<;2?82.8!E$C2017((:
@r5332
AGCGATGGCNGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTCCCCGATGCGGCTAANCAGTTCGACGCGATACGGAACGAGATNTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTNCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGC
+
+.?CE)%9'':=-F?92BG4@1B%G;-.@1;.A#&64D!<)BCH.+#(8/%7"9!(7#1<#2;=EE"B7056.=%=8..+)9!@7,,D?C8D8'E:;#A.#D,GF:F$9:G25C@=%,&>)H#95/,?5$1G("C2=F?&-=E/&17%'#.@1#+7'+!'B%6=@>@926$9<F8GD2A2,65H##$B&8<(0,91(7*:+54HB/1E3
@r5333
TTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCTTCTGCA
+
37<4;$$'%,//00+46&<;>'@$#58E.GC<DB*&"A;H=?9?A@&865B=@>";="CA-$0.)B,9@F@%D=(
@r5334
AANGCGTNTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGCAANATGCGGGAGATTACGCANCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGNCGCCCAGGCGGGCGG
+
%""')**#(%+"&!'"!##*'*'*%$%*&+%*(*+&)!#('%+'$"#&#"!"!$"#"!(+'*'*%%+&+**!($)&))#$*(##$!$!*"&)))(*'%''#$)$('+(+)"*%'(("*(")#&"+++(++)&#''!%+
@r5335
ACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGG
+
2(')&='"91;CG!!4>>5::2E/)="D>8&5F*1+8%-+(H/E")488-<4&E(2D)?&/4?A"/=1A/H.4E&C-C23;H!3E8>4#E/GFHAA(D$C8AE"<!-2*5'.-373(E
@r5336
CNCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAA
+
905@?96.GBD,2$74!403#G708<>1A3D:FA!5!(6":#G*B(8-7638
@r5337
CANCNCGGCAGCGATATACCGCAGCAGTGACTGCTCAANCACGGAGTAGCCGNTATNCGTATCC
+
0H>C#F/EA2B&=<%'2%(*BH><8+C/>#C*.<@;8F?+G>@9%@)/-89DG2;#8884*'>H
@r5338
CCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTNACTTCCGGCGTGANTGTTACTGAATCCCCGA
+
;!:A8>DD.>?D6E;>-8<G??8*;.C=G)+'>+8G1B;9G9.:()&<A4C)6%=>1C38-+>C"?@:'=DB6(=&*B
@r5339
TCTTTCATCTATAATTGGCATTGTATGTATTGGTTAATTGGAGTAGA
+
(5<1""-'*H?0-&5BC;."D8$&.D'>"<E/*C,94B%D8B,F*.9
@r5340
NTGTGNNGAACAAANANTTTTCCAGATGGAATGAAAAGCATANATTATTCCCTATTGA
+
)*%*&'%*#()&'&##!*"%%*(!*+(!+++'!#"#!(+)#+$%"!+&)&'!"#+!''
@r5341
CCTACAAAGCCCAGCGCGANAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGNAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGA
+
6&(E%'E94&59*@9HE<'2-3:117/''G70HH=&)/,7-B,G>"/#4%:0BF14#@$.E:.E5-0#>C.6AF#.83)0=.!D+&%+FA!E;0(2B1?-HC-1DG3@++3%$7F-?@<@>-0,A.+G3H<<$.D;@CC+G!5A1
@r5342
GCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTTCGGTACTTTTGCGCCACCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGNTCAGCCTTTCCCGCTGCTCCTGGCTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGGGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACG
+
B99<=7&1D*330=2DG!=">2>"F>22&0G+B,H8<D@*8*-5F+>@H>&+;?%>2;1*<.'8$BD%0)'50<(!#7&A8*!D544+%)2/")*'$"E:,/DA0+G-C49#;..7?!B-%H?9*7B:0(>/.#(=>-F1%4#A;&83'-8&E-H"2H95-&GF9?/<(8(;!;#814G+6%?(F!%$)HHF.)-E$3&</2*A%BA!;=)6DD3?>AE0'<+79D<%=6AE7-84C<:;.&1=-*$?'3B*<+D@-2,0;/.?F<4B2B=C4"%-'!A/*1F2<H>@#%91$9C):>G@FE9+D.;GE&"B$58%@+=*(55!?G73&!9.&<:2
@r5343
GCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTAATGGCATTCTCTGGTTTTCGTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCNCCACCTGGGTGCAGATTGTCAANGACTGGATGAAGACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGG
+
H=,-/37,12($AA@-<9,-,!*=(5;)G".;(6'1E5)?9.;8E;4?"*/@$3@C08;/$>B456)DC;88#-/,A3E+&@,("7&E$$E)7@#:"A6(#$,+2GE*H-,$,/5$A<<2,'2H!74!1&%@<;70:0G$!-09)2@GF?++#;D)3D=6,D?8+,C?A-H?D?D"9(,%<5*+G'H!E9.=D5A@C24-7AG>>@?$?)!3F6#895@0#8#=!@
@r5344
GGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAGACCACGTCAAATAAT
+
5"FF&")65F$,D-FE++F>""'%6D5H,(D35!*:A1><CF!,4E1*-8D#"1DF0<'75@897E:,=A,<*9?
@r5345
NCATTNNNNATTNNNTANNTNNGNNNNNANTTNAATANTNNNGNATNNNCNTTTGNTANNNNNNGANNNGCNTTNCANGTNNAANNCNNNNNNTNNNNNCNNTTNATNTNNAGTNTTTATCNGANNNNNGNGTNANNGATNANNTNCNANTNTNCTTNNCCTTNCGACNCATNNCNNAATTNCNANGCNNTNNTNNAGNNTT
+
"""$$$!!"$#"#!"#$#"#""$"!#"$"$"$"##$"#""#"#!#!!$!##!$#$"$#!#!#"!##"""$$!!#"!!#"#"#"$#$!$!!"!"$""$!!$!"#"!"""""$"!"!"$#!$$$!!###$#$""#"#!"$##!""$!$""$#$!###"$!!##!"!"#"!#!$#!"$""$"#"$$!"#$#!"$"$"#!!$"!#$
@r5346
TGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGNTGGTATCAGGTACGNATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGAGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGG
+
3&!6CCA@8(=0F5/F?$$>%5/)C?("B<H:,??,%+F=0''E+H@&@GEC'$+B4402#90.$2=0F,DFD28H"9DA"8H-H4+16!3#!-('B#8&'?<'C35GH3#%"&!&7D0$6?21%*)<@6EADCC,-:972&)(+0(&3+=5:B9GD1@1))'8G=":>H,@A&35H"B0'A:>*76'E6+0A,C$<856GA>,9B:<A
@r5347
CCCACCCTTCTGGGGCCGGACNGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGG
+
/>H3!D?+70+(*$&4@"=G@&9;60>E94-A5!3@@1.-(F;<5!E6C=8/-$@H/A$#D>0274G).$$>@$H%-%D-D'+0,")E:&DA#-.85*9<$HG4)/)+14F3@+B"E0
@r5348
ACCCAGGCTGAGNAATTCCCGGACCCTTTTTGCTCAAGAGCGNTGTTAATTTGTTCAAGCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCA
+
=E"?1(9(,):)?#+78.43C=;3)*@!<=3"%,%="/?(C4A9BDH/?A01%1>0??0+@1"FB,.'320&+=2$(0?*&EHG?414!-?#<)>#F&02.
@r5349
CGACGAACTGGTATCCNAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAGTCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCG
+
*+#6>.7C<8C*9GA;!'93:@7"$>(91H4E8:&@0=(C#C=(+;5DA-$/>D/"1"-H7@;=A1(:E&1D$1!!+.)?8DD:/@2)/:,!90827!#7)F:D@/24DH=F+F%3&H8HD&3B-9/FF3/,=+'36,->7H>E*%246
@r5350
CCNAAGNCGTGGTCCCGGCNCCTTTCACCGGNATTGTAGGATTTGGTACAGGCATA
+
&')&!)'!+#$!*"$!$!*'$#"(*&$"!*#*))+%$("%%(!%")%"&%(%#)+$
@r5351
CAGTGCCGTGTTCGGGCAGCACTGTTTCACATCGATGATTTCTGTGTATGACGACCAGACCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCNAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCG
+
(<<+73)(:EBC=7$)G065(4G91;.0;+A4*&G79729:5FDC9#G*-6'*1:6&-G,(-#C!@=81#6")F(:/)H73EH-4H!897F7E1*4"=H:>2@=F(?2*!38+6%@?.B$.;GH,5,/G<E)/B9:=;-=3DA77>3$C;F#C3CB!F.6G0?F6&H=/<24@+/'*H(#6%*@$%F"8H0E17+8+(';433%8$
@r5352
AATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTA
+
>+5-+C>?5)%..4))5B6H&(C4(DE<'509(=A%&A!@F=0=;#E6D543=
@r5353
NGGNATTCAAATGCTGCAGCCGCCCAGGNGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCANGGACC
+
"$#%+#&$$**%+'%*+&%)&"*"%()#%&)$++)#("!*#*!&$!!)%&$'!+!)"*%)!##+&)')$'%+)*+
@r5354
TAAAGATATCCATCTAGGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATT
+
G.+'+(0HH$"*&,E($8@=1)4H,,F?;?(DC*B9E42.!11.C49D>=7=&=20?+,+%50D&5,A03A3(01;A.HH,2H422+/="/91>)E)F<(7$"<>-E$>4*AC1#:$45F6%F*29FA984-E&<G3:23*>9!C=%:)7"05B*#536:AG2*4)C"!?+-*-'420HC@+F4)931*2:F7+7;0<8(F2F<:E
@r5355
ACGNNGACNTNNCCCTNAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCNCGGCGAACGAGGCGGTACA
+
$)$"(%**&)&""#*##+%%##%"!)%&"!$&*#'#$&*'*!$%&!!$%%#)+#"!!$&&'!($"%!)+(%&&&'#"!*("*(")$)+*)"("&$)'%'!+#%%*)#"!%)*&!(')&*"#(
@r5356
GNGTTTCCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCNTCG
+
&"#(#*%()+&(&('+($(#('#"&+*#'%+!*!+!'"$*%('('))$
@r5357
GCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGA
+
+A+:4=<2#%@$$84+@0'709-*,:&$4?1BC@4,"<@<:
@r5358
NTTGCNANTACNGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCT
+
$&$&'"#&($&+%+++"&)#*$$+%!)"*$'#*%)(!$+(!*()&('"$)$$$**)#$&&
@r5359
CATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCTACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTT
+
E"=,14H:D/,=+G?DGB!;)!%H?4%F*.9F%D("43<>&*)FA-#*B233:)EE.728/%6,,$9<('1-$2)?EE!(=HB>G7,:27).*E=806D;6?-*.08@*6@5=C$&H+?F?*%1(%)*2E6.+105"*$?0!!%.D47+9/4$,G5<:+#-8E'+#>7?(3%B>=%(=>#!)F0/>2BF/#)5,>A$=!'&.+%;
@r5360
GACNCCNNCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAA
+
$*$%&&#!&$+&'*'#"*%""%(!$+)*'%+%&%((")'&$#'$#'$$#")'%&'+
@r5361
GGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATANCTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTC
+
=)")&/8+1G4&B3!CH2+4$B*$6A&<:E6'7'%'/H/*%@-:G@39;+%(.#D8A,"!+H$+$(B);(%41B001@/,;E9'3;HF?6G5F%4)*9#G;"G8!0D#39G(6#9*E?BC
@r5362
TNTCGACCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCAC
+
&'#*##*)*'*+*!+$#%'(!%!%+#!&$)+'(+)#&$$!")'+!
@r5363
GGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCT
+
E9-=5<8E:9F5C,%$B0&"3'FF<<A>C(0GH;@8A%;3/'9G83,?5"$.9#D'?A#
@r5364
AGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATT
+
78?G1&'387151F6C7.#!F0HCA%/-!1*/2@.C7+!/3E*=
@r5365
TCAACCAGCTCGCTGACNTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCG
+
91<A30H8:=85*3$)"5',$?4@*1&?,C-,7E(B(9$!<6(=F%'D/085!!@'C@;.2)'876.DA9+,'D,
@r5366
GTGAAACCGCCTGCGGGCCGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCNTACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATC
+
,G!:<+*4?44'?,9'"&@<?-(-"!.5CEF27-1.*6@2D%;;#,331A=9=B,<D6?8>6>77-1@$.+/%4%6G/G3@B2#>96FH*8:75F@)-$5%;)4"D!):8E&.;3D=F$:,%B7/DA,F9853DH
@r5367
AGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGA
+
H".F;6#5DB41:1--G-34EH1!G:70(>7F$AAB%C>.$*)C)299&>E3"G,:G%3>#!9-G8177BH3@
@r5368
CAAATCTGATTACTAAACACAGTNGCCTGGATTTGTTCTATC
+
9&-@:=E/*4-$3D9=&.;.8F=!%122?-9#-3H'3*$?9&
@r5369
TTTTAAATTTTGACTTAATGACTATATCCAATGAGTCAAAAAGCTCC
+
+(+!+(*##&##&'+(((*'+))'*"(%#%$)%$"+'!%***"*'+%
@r5370
GTTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATT
+
#.DEE)5=(9#C.'07$&=0('9:5+4!9>DD43?);6&#>>%)E53,<F401H<H1E)5!(!9A2!?&-
@r5371
CGNTTNNCCGACANNTGATCCTTNTTNNCNNACNNNNGGANNAGANNAAAGAACTCNNGCNCCNNNTNNCTNNGNGGNAAGANNTNNTNGANANNANNGNTACANNNNNCCNTNGNGNNAGNNCTCNCANTCAGAACNATGGCNNGANNGGNTNAGNNACTGCNGNGNGANNAGGTCAGNNACANNNNATGNGTCAGNCANCNNNNNAAATGGTGACNNTCNTGGNNATNATGGNNNCGCNNATNCGNGNNCNNGNCCGCANNNNNNNNACNCCNTNTNCCGNNATANCNNCNNTTTNTANNNAANGANNGNACNTNNNACNNTNNGTTNNNNNATATNCCNNCCNNNTCTCNNGNTCNACAGTGNGATGCN
+
"#"#!#$$!"$#!$""#$"#$!!!$#$$#!#!$"!"#$#$"#$##$!#$#!##$#!!!"$$#!"!""!!"!!"$!#$"!###"#!!#$"#$!!!!$$#$!$!"##$!###!!"""$"$!$"!!$$#!$##"#$$!$!$$$$"#"!$$!!#!#"!!##$"!"$#!#"$#$$$$"$"#"$#"!!$$!"!"""#""$#"!#!#"$#"$!!!#""$""###!"$!#""#!#!$!!$$!"#!"$$#!#!##!$"$""!#$$$!#"#"#$"!$!"""!"$##!$"###!!"#!!#$###"!#"##!!$!$$""!!"#"$"$#$"!#"!!#!$#!$"$#$!$!$"##!$!"!!#$$##!#!!$!##$#$"##$#$##$"
@r5372
TACAGAAGGGACCGAAGCCACATCCATACCGGCTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCNGGAGAACAGGCCACCATCAC
+
%13<'/"B==9=/;!>?3*H!6?')6-DF/E5:4.112B+=@.4;=DB2;;D"%D)/GD%(,F:"-'&.D+<C'"$CFB/))C=-?%/F!C
@r5373
GGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCA
+
!+')$"(')&!$#&'"$&%*#+'%)%&"+"#)%'(%&!%!&!**)$!"&+$')'!+(%*")()'"**+'#'&%*!$&$$+&%'
@r5374
CTTTGATGCGAATGCCAGCGTCAGACATCATATGNAGATACTCANCTGCATCCTGAACCCGTTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACT
+
:F68AH<?>(:&=$E25,2:=:"'C:#,$!534@!4-:"F!3&'B,'*5!)::835H)=5H!"=<>*("#G2%A.7&!4*/.;H=!GE?B-*&5/#61?:-@B17&87HG
@r5375
CCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATT
+
"G?B2"&B$9/1!/G?1>@3=#;'!'B#6:D=*$'G&,81.%#HG@@6AH;E'!D>3G)*$09CB/D62)5'<89(<2=$26G;
@r5376
ATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATA
+
A7-%1%%8,%?G1!<<H)07>F%-+'.D:'>=F9C0>;"/C;HD"C6.46*#,#C:).<DA347.9/E:F:15=4C6279;-)1H%,'D1CD:'912H93)(G17"9ED2E9%9'%==<E2#)4
@r5377
CGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTNTTGCTTGTTAC
+
2$?0%C')$9*.>,49!7F@"8=47B"#415H3ED4*8$?/+(>#C>A&(8('&)?(/@9F4-,-DGH+DG1(4824@7,A(GB<@D6#*0C)AE0&;,D9'"930/.&7@-6.-8>B(H.@<@"F+7H;&#5*$4%4@(
@r5378
GCCCNACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCG
+
(.#G"77243,&,:222;26(>F2C!6H-E78+87)'#8H+(E*B2)D97515
@r5379
CGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCNTCATCGCCGCCCAGCAACAGCACAA
+
#"F>HGAD4)%!@;7(.+::'G#0>5,?:9!*9&15%5<;5#6)5E/D&-7?;3*&2("#H8D5D%58C3>#*1*0(#4!E-"A"31>>;);A6:?,FD!D'??
@r5380
TTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGNTGAG
+
H3<;"(HB:FHG;*B,<,/505F'6F,!D:43;)A-(=?%%$A8"'"$?!#A$
@r5381
ATCACGACATAATGCAGGCCTTNACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGG
+
+C003E8$)4)'5)#0HD:/"6!@7C;FG:<D;0/096)1+GB*;5=D@&=F.G;CC/4(?*$9"<'D$5#HEC-18:;,"6?'4$<@&4)>%F*B034
@r5382
CGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGNTTCTNTC
+
HCEC2@>7!A@'2-1=?B93C,#?$C:)$!H1=:>?A'745C=F(C1(>4=#@%17)$+7BF0&0@G3BB&:=@FE
@r5383
CTGCAGGAATATANCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATAATCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAG
+
G'0>'B%G;<63=8EB<*5:2'.H="!5)?F<3,!+)48&!@:)&12B=G=%/1F$E-(.!#D+&'4AD;:-5?"?1B&5.>FF:.8$4AD2;?1G3>86!0+6'A;#H,2;-2;F)8$)9F0=@1&(0?3@>.;#?*64GHC+22F3/6*>.
@r5384
GTTATGACGAAGAAGAACGGAAACGCCTTAAACCGNAAAA
+
E).:=%5-C-=1:1D"41G/>/"G/,;,*GC9(05*-.C$
@r5385
ATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTT
+
G#43$@&A#'47?DH,4;0*%(.H#,?;A5C.AC%(41F%E18@**B".:F=003+,"*=#;(@DA>#.E.@HH/F+@+-+F3H?F&0"-!<G&4<#H"+
@r5386
NCTGATTGCCCGTCTCCGCTCGCTGGATGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGNGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGN
+
03.:G?:7'6E,-=6+26."-(59!,9/@'C'9#5!+:)<:89)$+A==/,=.),(6.3-776F5>B>.%&D-#E-1,B$!-6=6DA;9EG&5F%&"$!>H?+0009)%$H'/=%@:BD02BB4)#@:F-1!6ADD,B7B8#H1C8,+(&3DC!7B.."A#/3278:*35>$E<F'FE5,"F%8?>H2+#"979"
@r5387
NCNANTTNTCGANNATGACANNTTNNTTCGTGAGCAATGGGTATANNNAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTNTTTATGTTGAATGCCCGGCGA
+
%)#!#%(#&(*''"%"***)"!*))#)+$"%))*''&%'(+'')(*&#%*'*!&*$*!#''(*%+(!&&#$$'*&$++%(%!&)%!#$))!(#&"))')"#*''
@r5388
ATACCNTACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAA
+
*%$!""+'+%**#)+%%+(**%)+")*()$""&#!$'+'+*()!)#&
@r5389
CNTTGGGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAG
+
'"#*#!(*'++)+!"$+&$+&()"+#*#*!+!"$&("'%%"$((#+)
@r5390
TTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTNGCTATACCTTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATNACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCNAGCGAAATAATTCAGGGTCAAAATATGTATCAAT
+
2:5%#2="3?F(393.6#E.>7'3%'(H7&(+HC'321,=*!&("&(5.D@&8=F7;HC<6'CC(G%!GB&C"B9+/(/G!E$<%"76D0A/#H8+0,52-E??8H7&/1&HB7%6)-9$>@6E2,?="9"!-9!2$7&8FA%-<A!G?9,D-B9GH2!7E6/$(@&/";$>@.:(;*,546$0!!&<?HF');';A99"2!C5A7>)7(+4'!9/:,!E$CD$2A2%-B<D4G42*41"05D'&"46E7(A%A(-H'?F+%&/6-!:.:5HH!A*GG1FA!<')-3-039D04.*+/:&H)@(.;B=<E$4)'@"0C)63&:DD?;H:$4,>/DG*7/
@r5391
CATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATAATAAAAAANTAATGTTTGAATGTGNTAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTG
+
5/:C.16E43.CBF/?6B;08D#B"F?@55B,2<(:>:1C9DD&.B1-D<2"&B9H-+>@->/(GC!*?B/*D!+40E<*:A6?6?+9:,7;4+'"$,658A42+8>)>4!&0:.,6@*C,H<F2E>?>!7$(7))##9F6&4F
@r5392
ACTAAACCCACANTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATC
+
30<,C=&#A#DF!;%;#H-91>B03C.%$',6C+,!64F5'"#4%DH>32/F'*$(4,-526>;&E11!D15%.#=@"-$*&$62E3>',!)57?+C5%4D0*A<(5%G"$90A@>41#*5F@F%>5F??=A!D6):@$86?/<&@CB8*G-4'
@r5393
CACAAAGCATCTTCTGTTGAGTTAAGAANGAGNATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGG
+
$':<2-6G6F/!?';56?$.()109#'+!:GFE+1<H-7(&,"8(E6*@165=/@?!F&<,A&G2>/;*3!)
@r5394
CGNANNGNACNNNNNNNNNGNNCNNTNTTCNGANNCNGNCNGNNTGNGNCNTGNCNNNNCNNGNNNCNNCNNNNNCANGNGTGNGGCNTNAGCANNTNNGNCNNN
+
##"##!$#$##"$"!##!$$"!##"#"!#!!$#!##!$"""$!!##""##!!#"#$#"$!!#!$""##""""##$!#!!!$#"!##$#!"#$$#!#"!"$##!$#
@r5395
AAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCNACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCAC
+
$+%#&))!!"$+#*##'%"##)!)+##"&#'(&+)%'"!*(#*#%&"&+&*%#)'#+!%%'&#("'&$*'+$*"+*#$%$+$&#!#%&)"(!*))%"
@r5396
GATTAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAA
+
+##+##+#%('#'#*"'+'!#"('""'*&%'''")%&(!($"'&&%*"#%"*($+()"")%
@r5397
TCAACAACCAGATCGCCTACCGGTTCAGCTATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCC
+
14'$7()5E&1-31C0,&$C0)%;.).#0C'!0-=AA?>@H2BE&;%F@D>G'/=.-F3?!3>1'+0#*&*<">#+7!&%37C0)""!+B*#9D(C.3++;</;74H9;3=1C5A::+>2H=7/D9<?3-*C+&<E%C%'#CD59G(-H=4E;%-+
@r5398
ACTANTTGCNTANGCTCTAGTNTTTNAATTNAGGNTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATNATGTTGG
+
%)"%$((&%&%$"(#!!)*!)#"&"#(*&("'($!!+!(+%!'$(#+%&*+%#"!'%#(%&%#"%$&%!(&#(+''&#"%%()"($
@r5399
CNTCAGCGTCGGCGCAGAAGGGCTTCGCCANGTACCGGGCGATGTTATTGAAATCTG
+
%#>7G5%7<<=0.F=4/6@9A:&,A*5:!3'=<<4).E'4B$)&/=H@G>A,(&?67
@r5400
AGTGGCCTGAAGAGACGTTTGGCTGATCGGCNAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGG
+
*$+)$$"'$##%+$')$#)("&")"#!(#+*!$((+$%"!*)!*!()#))!)*$"'$$'&$'&'!&#+&"&!&(#$'$%$&+"'!*))%%+($!%'#+"&)&%"#'%"*!&#'(*)%+%%!#)!%!+$'#
@r5401
CGGTTTATTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATG
+
%!*+')!"%+%)&!$*&$)#%#)+"((!*!#*"(%++&()(&!
@r5402
CNTTAACCCGGACGTGCTGNCGTCCCGCCCGGCAATCCGTACCTGATNCCAGCCGT
+
+#10DH>BC9'.3&E!;#:/49(4%$;$:24:$>)5@A%0*7.):*")7H=@.197
@r5403
CAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCC
+
A.'"6*8C5-+.?@AB>A4?,?&#%2/@.AB.*/A7D@,<H
@r5404
AACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGNCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGA
+
HD+2,1)F+&-CF3$A$(3H@)6A+B&=!=F<;."+.BC4E'G,=C.)),/E";@%A8D&(HD7!;<#0*E5ED"EG:0<H2?CH$89;E2)-';'53($&;.!9;.E)E8.:C&(;D716+70#H',:9GHC(":A$<=-9*F2#%<@1.5+*8@,1=DB(24?A<592)(--?/9;1A8"88E%D<8:)H(2-'CE7$9+:
@r5405
ANGNAANTCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGG
+
"%(!'""+"$"%"%*%))#))()'"'($%#"$'#**&"!"&%*)#)*#!*#'#'!*"%!)!+"
@r5406
AGCNCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCTCCACAGAGTGCACAGGCGCGCAGTG
+
'&#"8-;23153-D6<*'..C0@2#%$/%"'6:4-F"43:2$9">;6/7%("#$H)H,6EGBE#&27?.$D%<
@r5407
ACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCNCTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGT
+
<>0&6*62?,DH0F546>:$.G3!>+<".G@$9'21#+8!("B0",+1<.*8"0#1CC0*19:4$D:8A!E?:.&6&6=C#*!76-7!/81555@10(=--C3.:2D#C1;#GDD((;8B:))?C5(G1H/F#E:7:("!33#&0(7/*7=3FH'/"/1!84'90/+,(G3$A&+G3)2B30=3):+=*8!)G:;:<E53,H;F0E6=+C"E2'>!$:=%3!5)@=$4$9F676%
@r5408
TTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTG
+
&4#33E'46A4C"E3#(0/'&9&2D<'F'A&;=%)=#%?&8B<?F.=01(@1
@r5409
AGGTAAATAACTGACCTGTCGANCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGGGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCNTCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACC
+
4350"?*)F893:.GGD+C762-7%""?E999*F0.F%%E+")9$##C4B6&'0&1H$.>)/D"-*-F=&0H0%'+EE+0.HH@&02@H21>;A?@%,31(',8C#>?C/+132?==+:+03*-9;9@'?-#088#D@??$>0'+:&";?+7$AD*-&FG%:F>&@B37H%@G%8@*29D?0.1':37A5:,88&78HBB1'?H2/9G8&-E$3C-%9628=A).9H4/4>DD$9&4@#"
@r5410
NCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCT
+
#(H0962)(A/(5AH:*=;3$C?9=49D;%E43$@,"3F,/A0%DHG>-(C=5D188:D/%&1/.#10,&4H=&>
@r5411
TGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGAC
+
69/<=+472>EHBH1'-F-190H?6/>!3;&6>D<*:CH>5$"AH)EH@3"2064EC,:2D/(E>*&"AE30;0?/C<$.7"F/"8)"4
@r5412
GCGAAAAAGCGGAAAAAGCAGCAGAGAAGANACGACGACGAGAGGAGCAGAAA
+
21>@A9!2)A;7E'6<'C+>4A5$!'72/F%@,%E.G5"053B/#2>1+D1''
@r5413
CATTGANCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTCTGGTGGTGTGTNGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGNACANTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGG
+
E9D6$F.,9@@@)=H!@C:$$*7%F*.".88G'3C9.$6@031G33'B$%FGD1)6>#95:G4<)<+AE;31&$>1-!/@;?=E/:-%A(1*"5B$E/>#1D*F@(*C=*;#1C!F,!-+"9G%D=&+C1H8C4ED))$-(:+-7@-4D-0(::!EF-2#5#!,E%93#'*",?6G5@'-8:"8?-8"5C4,@,)0'G9/D;9..14*2;'4C5F/<7?H<$4,7+.DFG'+9>HB7AC6AA9>#<C5*,B!:<
@r5414
GGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTC
+
H$+-8%ED+8BG*90'D176$<HB&17%#7>&9@$9$AFH5-D5C69:(,F'?3:?DE@>"=GBDA0?%2A4+?"
@r5415
NTCGCGGTGATAGATTCAACGTATGAGCACAAANAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGT
+
%(+'%'#+'$%**)(!*$+%"'$"+&&$##&%%(('%%$)*'!!#&(#%&+#'+(#'(&!##%%+$"*%%'#%
@r5416
GGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGG
+
HA*E4-6-/$D"4F1CF&9BDF807=59:=+:1@?17<H)9C;8&*(94BE$;E,#*/7$,*18A7H<"*3F62-/31>G?/)9.1>%5%
@r5417
TGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCT
+
27A@0?:?,8H-BF,59*228<=<'#*,G.0DH%.&(C(G3'(0,+:'430)*<=#?(0)?&=>;/577)5$A3,F8F7A&."0
@r5418
CATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACNTTCTCCGTGG
+
;5?>7+?:/>7G5,2ED65'FC.BH3/)%)3A#49!.8,9,0->C/+
@r5419
CTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTCTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATG
+
DFD$#.=$E9*..>EB,<?(?*7)?976+?<7C'6@32@CB79)&=4,%G>;A4!-B$5-(%*="3",&?))6*<78
@r5420
GAGCCAGCGGGGATTGTTCACCGTNGTGAGTTTGTCTTCACGAAGGAGGC
+
)5H1<+EE*/E931,'8<<$!>CF92)G:F/,4#/)/(*3C$HB?B+8*?
@r5421
ATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGT
+
?$!,E(7C:E<)B*()-DHB?$...;9%H"17%F2.9G-%';F&%;0#E8,;+H+".-6#71-.'#%56D,&G%3'=(08F63HB&);@:1.$,H?<E:H)'B(H*/A1B;,)274G(D@FH@
@r5422
TTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCG
+
=,+H.&8A@,3CD7'->6%80')%&&&'!4=/4,G.@9)C///'"'8:8:CC;*5+:G&2+25C93%>>'HG$%D@.D@(HF!+'&B$>BA,28'42EB
@r5423
GCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCT
+
99B-%F=H:;*C;))4574#23@6;A&4E!'#=0.@0?+*A3=:+;9F3;>0D<7=96$1FF<CF?=#F4EG9D;D)6;-&)F/,)=)&H*<1+EG635)6A9!$;E&-96@51%5
@r5424
CGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTC
+
$G6D/H/#FB@('GG4*H=-#0$0A;G75#!0:96*'!-C61&$)DC"EGH'AEA-1F!$+0?9H+@3&98+GF3D8<<7=13'4(1)!A8!*5GB=+?""C-H>)F>F)*4,,9G
@r5425
CGANNNTGGAAAACCGTCAACNTGCAGGATGACACTGNACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTC
+
*#'($%+&))&#)''$&(%"'%'*&'$"(%$%"!"$('"&*$'$'(*#%$&!%!+#'$%"$+#!%(*&$%!")#$#%)#!%#+!'#&!""
@r5426
GCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGA
+
<%.,D+>H)<!#4"=?<&B7H+E'*D/*C4G(;C3:'6@)(-F"7<B8A23H%H,
@r5427
NCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTC
+
($#+("$!&&#*'$+*+%('$))%)*%#()$")"!%!&)$!+%)'#&)+"&*"*(#"%'!%&%&*#"$*#%(&+*)&*)'"#)%+(%"')+#
@r5428
NTGNCAGAGCGCGGCCTGGCCAGANTGCANTAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCTCGCGCCGATGAAACGATACGCGG
+
"%)$%+!+++$((%*(*+$&(&(&&(#)'!%"('&(&'+&'%&+")'%()(%!$'$!*&('%+**&"*'!!"++&(+'")#$&(+"#+!($+!(+(%(+$!!%!&$
@r5429
GGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTAN
+
0F9%/%9,%DC1*/(G$5>&!69)<(F<<G9G+!)H</93)3AC03B3!"FH76HD2!0+99&</%/$:/%%*%G+B%G;<95#9->G?
@r5430
GCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCNCCGTGNCG
+
5E#%"3&/+0DA,'"F'>G1,"F8;+F+,,(->%+66G>/563"2CB+4!1*33
@r5431
CTTTCTCGTAGGTACTCAGTCCGNCTTCTATCAGCATCACCGCTTCCTGAACTTCTTNCAGACCATCGATGGCCATAC
+
':6>/0?=*%3;"':.9"8@!%G>DFF("),4+75!*D3E?'3@206&%G6&/(G2C3')#@D6=B!=::-A"3D".+
@r5432
GCCCGAAAACAGTTCTGGCAAAACCANTGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAACTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCC
+
:76?H>HB9!(,)BA'$D7/E'<D$"=42@G8$%#2E>3D7:A.AAF=E=6&'%@&">&(+(06G69&<54#D%?8HG5B-96#%.?'?!:>H34%;07/):5:24@A.HC=@1#H%=&C*31>,&!;4&C4:?%4:"-(+&H08,$3.!B6FF/D6&B8+H35+:<<6@75+7<(?H
@r5433
AACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGGTGCCTNATCTCTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGNATATATGCGTCACCTTCACCAATAAATT
+
0>5+9(!1F#09:!#>--,(BDH%%@3=@%B<)@$%""=<6'F#+$3.<B8BHCH;++=A<C>D901BE<5461FG/3)>G,*&+<2A(F@5%%9G$+!"E%B*=C<9.466D$'$)>,*8C*1/7.?%!@B4>!<*+&@*,)!FG6&&A$A5>31#2'+E3@%9-6H88:A,-#&1&H)4)70H(0
@r5434
CAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCNATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACC
+
B)#2-E/?$%:3C+484!>>=7-C1A)6,0AC*:1-2?-"DH571E:F@-9!2?*:&:/3'"13$42B1$"%44423>6.C*.0@:G%.F+F3:92A@!#&5$B-!/0/,5="7A;,3H2.5CE#F$)E%%/'!H
@r5435
TGAAACGGGTATTGGCGGTATATCGAGTTAAAAGATGACCATCGACAATACTGAGCTAATAACAGGCCTGCTGGTGATCGCAGGCCT
+
7#0>+"DE=6*)H:5-$265.(21G8!46$.HB=511@9$4?4>@B%$.E@-':?;?#<(4);/,E:3;)+33(?:@)(2;0/'HC(
@r5436
ATGATATCCCGTTTCAGGAAATCAACATGACGGTTTTCCAGTTCC
+
H%>;(4*@>=5A4F(:<C!.(7'"3!B47>"1(4$,3+B$+6H5!
@r5437
CGAACACGATGANATTCACCACACCGCTGGCGTTTAGCGCGTA
+
:9!-.F<2'.!(G7**,?%":(E/7*!%#*)*+#1B6+<@(?*
@r5438
CGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGA
+
,5.95:!/82!'C(7:&58=66-F=#4%0(65%$H=58F/?!*513>$4C;7264(9?>?B>?9'-8/G7@9&;1?'(&E<7(E.5:176=6;2&4/%+&H14&G'G@@G-#FG$(:*',!F)F"-!E+6-5A(3F;4=7D=G0;%9!=503D,+%4),
@r5439
TCACATCGATGATTTCAGTGTATGACNACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGAT
+
C0A=73E42,?B#H)!(*5"1;/?81(""07*40<65@=)<@5-A09-;D@<5*$@=(A=0'+)$+&83:"0;!D)HGE!?"9?A#.-5+9
@r5440
TGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGA
+
:!)E#$#=C!"4$.4&CC?&8&=),BD./E$;"//9"!<>9)>?5@=
@r5441
GGAAACCATCACCCATCANTTCTTNGTTTCTGGAATTGGGCAGAAGAAAACTGTC
+
10-H>.HC#!?'5,(%*&7-)5-:'--39F#$<#23(BF*8*=F?@6/41?!7<(
@r5442
TCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGG
+
CH+06-<22D5;4?@4!6+,"0=6-FG/A1(B'#3>*A32@%;!.=41;/%2H<)9*<?
@r5443
TTCCTGCGTNAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAG
+
,7:-FD8#C6;/B!)A9E99&6:5>57BG8'*-!"E(?DC!'?E(1C/)H:B;:5@:6?>&),=9*@7*.1#)<$7F78.3E.GB(''9#.%'97-@/CH;8$C#+$<E763)#$5;
@r5444
GTANACCTGACTGTTCGATATATTCANTCAGCAACCCCGGTNTCNGTTCATCCAGCGCGGCTGCTCTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATNAACATGTCGGTTTTCCAGTTCCGGAAAACGCNGCTGCACCGAC
+
&'*"*+!'+%!'+&%+%'!+(*)"!("*(*#!##**%%''+*&(+(!$#%""#'#)**"&%#$"()'#""%'))%!+)*!'$$#%&"'++(+(&!%&&''+$%$$(!)'!&(&*+)+!*)'!)!*(+$))*'#("&*%!!%')"*%
@r5445
GCCCGTTTTCTGGATGCGGTGAACTTCGNCAACGGAAANAGTTACNCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCNCATTGAGN
+
6<F,<E,#:60!%H;'C>42B.#4<&H$F7),6H;1G5D66G#8683,-B160,C:*);<E=3A$3$2%$-<<C?42%79AG"H'+*9
@r5446
GCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGNACTGTTTCGGCTTTTTCAGCGTCGCTT
+
H;*9C-6'B(=&E&3$)0"!774?A#6*,--)6#@E7!)=.D6(EE;C$CD.C$G&:+'5EG99%:5862+<,?CA:&:C
@r5447
NCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGAATGAAGCGAACAGAAAAGCCCACTGGACAGTCCGGTACTGACCGGAANGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCT
+
!':78C#%B,2FD!552.1%GFCCH69264,<"+@)72H$-(4;B"&,56ECE'&*G!!=B;8?#71E/">%-69GH?:'!@G<%@!1??&?1D?$*:"76@2;;5$'-2+ED4(9379&?0>0:H?-!E8+C;F.!1#-&&=<!,$.3&8/9.?2B&)#!)G6D/%&CCG2.,>1<4">'6E2$F:G*001!6E+&?)
@r5448
NCTTTCACTCCATCCNCGATGAACCATGAGAACGTCGTTGACGANGGCG
+
++'%+++#&+!'!(''""&!*)($'$&(#%"'(!+"*%'"**$$*!+#'
@r5449
GAGGAATNGATNTTCCCTTAATTTTCTGGCGTCCACTGCATGTTAACTGCCTCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACTTNGCAGGTTGCTTTCAATCNGTTTGTGGTATTCAGCCAG
+
+++)'("&&+%%*)#&$+&#')")#!&"%#)!+&%$!()*&+)"$#"&'&$)*+'!&)!)!)$)+*+!!%'%(#$""!(&%))+*"%#%%($')*%'+&"$&'**&+!)$!!($"$!%*(&$#)(*$#%+"!'+&)$%%"$
@r5450
ACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTC
+
H'++6@99)0.5+<1FD5C0(>!333)?+!%(@H$./DBG>5.#!
@r5451
NCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGA
+
">;@#/<D@+<%('(1"G")B!.33.1H.E,=.7G$C!'BEE@@?%BF)52E383H
@r5452
TGAAACCAGCACGCGGTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGNCGAGCGATGATGCGGAAG
+
F%BC#/!6#+G9;(30(:'1D1!)3/'"A81+6*!9<!*@=)7C96&.:G4965%AFF8?G8G"CC56!5);39#6#H=?C&EB>.+4@3@>9-+D"((=0:+*"-*;1HH:.(!B&*@%8/;/7EA14A.:09A(93+B$8H#>"&4'$.?16)5:+*;,
@r5453
TGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGNGGTAATTATGTCAACACCGCC
+
BB*,>5E,HFD;*CD,HH$<BCE;CFB8H8G>@DG?@GF;62@47<$C:>$>(46)%F4G*:$E3)(DG;!/-5(-@>H530+=G7='1/=GE:3=3+6G,D&H;((076%>A4
@r5454
GGCTGCCAGCGATCCGATGGTGGAGGGCATTCTGCTCGATATGGACACGCCCGGC
+
:9$((:7(2D*.F=8@7G#-'-D1&)6-5,H1<,2%8&5#F-+9)C/=51%B+&?
@r5455
GCCGCTGGNGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCT
+
"5/!?A<((4?$G8+:).2&88>3(??D<-(E=660"%D#@;/E'
@r5456
ACCAGAGACTGGCTCAGTTNGCCTTCCTNCGTGTCCTCCATGCTGAGGCCNATACCCNCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTNCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCA
+
-5$:/%;('"?A64=?4=63*91;D'!#%G:(!G*F$"-G-D3$-,>?.1)DG%@7,A6..)?F#$H8"".E0'*+.-82+&).0#C)(B5;=A!$8AB$DF#F6GBD2:0B=?H/C%E0#!!G9F?HBC4=300:'6"";/0B)9=*A%3)3C"D!!:A8:29/"-D,06/'9!5#$62BH=:C+G=50=B7A#%(G)>#?A34$7$7B>?$.E-!7F//:ED5'#'A=9GH/(.0-*,C"4/::-.$*B.CFE)G45A.60:%(E%%''0*009&"!4*B,<B@-/H9%D$)19*4))"F@@"B6G(C0/&5-C7G1B9-%A(#CHA,7
@r5457
NNNGACCTGTCATCACGATACTGTGGTGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGC
+
#!##'$'+&&)"&&'&)"!)&#)'#)+"##+'+%'&&*'#!&)%"*!())!*##$*#(#)$(&)+)%
@r5458
TTGGTATTGGTGCGCACCAGCATCCGGTNGTTATCGGTGC
+
;'.#=*6C2#$/9/356E%A9/4.@,/<6"-3(D':DB=&
@r5459
ACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGNAAG
+
DF+8+B8A.DE02,C;-16=7=F;<48H,!,E:#9&5:>;
@r5460
AAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCA
+
=@,?'5BCB"H%(0&07434)!&;-?$(@:;/*D#9<;B6#E(@#0A!8*=?9GB8602D
@r5461
NNCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGNACCCANTNTTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTC
+
#":'!34B/8+%E0+$3743B1%(?HCH:B?!!->+>1*;3<39:'%7B'3$@#-(?E'D5!6,!@>FD9.D+98877,*@?G;25()%/!>EG6,4:@/(712CC-F=B9+C5!BD.)F)62@-48.130-*/2*'*&F+?@+1D:D/F@D,2D$D$3B-F89*"'*FE**E;
@r5462
CACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGG
+
48:/-''G=4C3)A9B=+8"."H*7'%GA8H%"62:#:5$-"+/'15#$'@&=.&$>36<$017(6.'25!$(;
@r5463
AACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCNGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGT
+
)E93$?-'C>)1G"G9?57#H4:,==5F)!#?.*@/7D9%AH14C<,&'=/B>+$GF'0%D,F0('>*.F<32'BG;/G(?6*71G6)83,15*@B#))<5F/9=94$6A030(&0'G&$*@G3DE-;D2AD74)?+@1;-2%44/6G.=/(&.<H,97
@r5464
CACACNNNANGGGCACNTGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAAC
+
**$$&###)#'!'(*%(&"(+*(*"*)$"%$(+"!+#%&'#()')$(!!*'%'%$&"('&)&%+''"%'
@r5465
GGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCNTCGTCCGCTG
+
7D7:C!F.$EE&0)H,3C(#A<-/D09=*!E-,#/D.H6&,+*+/'H5G7G9-
@r5466
GTNTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAACTATGGTTTTTCGTTATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCG
+
EH;G04E9)&82CFH:3'&?$@8H+!B>":!?;&<A9<%+D;0335$31C,9(%0#:!9"A=H,$B0=3#9D*<16;B5!"E;'4565.2=<
@r5467
GCGCGTTACTGGGATGATCGTNAAAAGGCCCNTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCT
+
BE=(>)3+6A132E/.;!+D#0C,D/,:?:>!+8)%F>.:E+4?1D2!E"&0>$89'9!,E("
@r5468
CNTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTG
+
)!++&(&%&"!%(&+&'%'(($'"&"'(*")#$)$*+!"!'($+)&"+&"!&!*+(+(#(+()+''$!!'''$"%')&!'$*&!""(+(+%*"&!)#(+)+*(*'$+++'""""+((%"!')&"!'%#%
@r5469
GCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACANGTGCTGAAAGCGAGGCTTTTTGG
+
1-!&H<9>#GA2*..A84+@27%B!895<</?;)952.$01=D449"BB"1'8H6$9H=4'00F*4%BHF%/:E+)E:4?"GFF/C*%?=HG5B/2?$<B+3=;,GGA+-.!/86:A?>16838G98/'H??/5HHEA@6&<"EGA3)1F690706A3%18:
@r5470
ACCNCGCTCTTACACATTCCAGCCCTGAANAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCAC
+
@<B0@>1E!23HE-6"*,5/'<!'%G1("'CF98H=@<6-:H*4<<(A34<CA$=/!:+B&/3B311?=B(+#:(+-26B:!1AG2%
@r5471
AGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAG
+
>:'?>'H%H(=!4@!;;:HH,)0C;*$;-H&01/C@G0%&"+A6G#B.'3/8,9
@r5472
TCCGACAGGTTATAAATCCATACNCCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCG
+
++2)*99=2-%E">6%&A</D284+7!$@-.21B$$$9:9C8%9E6'0CD%98G12@5=!=.B(.6231'B;<>E/E/'
@r5473
GCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCAC
+
43-#0B';&&'"*A,)?8;+=<E&(.B4+ED+0!*0,!@@,8-?)H55,A11D'E>?6/@
@r5474
CGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCCCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCA
+
:EFG/+%D</9A<<&.'.C#)5C"%@B3>+@'?3.#*('.##3@H#/1$41?*96$)(#=BE9"==FF5A>))"*H,14!=<D&?"9E&)F-@'%7>()-'?)993&2;F%)9:9@'F?G.:B$@5--/.=:'E$:GC(<?'3CB7?8/C';@C.D@"=:(0%>$=B<?>>F'2&H*!
@r5475
CCGGGCGTTTTGTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAG
+
+!A'C:HA3E&>,%CF-$3/GHE@/,1!=>66@H1>+(@ED@85(6&8:E*@2>G#.*;B7E=#G8)5;G722##.,>H7"=73;;@E%CH(*9/D$&B,2
@r5476
TNNTTTCNNNCNGTNNNTGNACACCATACGGAANNNNCACNTGGTCGATGNTTGCAGAANCGTAATGGTGCG
+
("!'%&("$)&!'(('(%%#&&*&'$!''('%$#)!$&#"%#+++&#&)($*'%")#$!$#&$'")'!#)*)
@r5477
GTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCC
+
9A34;7.)>#A=3?@3!<(3AB/(H<*G('50.<$=5508H"G2FABH,434DG=>!1;@':F0!>3@(=B8'191=#;$,'+.FE>6F68CC)*HD+#B41F<F9'E9)>/:##G9.D&>F&>B)
@r5478
CNTCATTGTAGGCGGAGAGCTATTAACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGA
+
')>#+A7E66+$*9F=-+)?4G.3&9A1A0:(F&02'=6+.+D->'4G-D+%+:?7>1.F*A-3;2*E:!G%41C-;7"E+D',A.8=.<"CA".F;E<!=<'30*"A.G92+<?&,)/3?A6
@r5479
AAGTTCTCAATGCTACTTGCTGTTCTTGAATGGGCGGTCGTTGACGACGACACGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAACCGCCCGGCGNCAACCGAGCGTTCTGTGAGACAAATCCANATGGAGTTCTGAGATCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGACGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTGGATGATGGTTACNCCAGACCATCAAATANGCTGCTTGAGG
+
0-EG6(#F-0)F%0#H)*E1&FGA8B0E**"G!D.9.?E$#"FGG5))!">:*+.#EB!C)*5F3'850B/%'%'6&G?$D11%@270;$F/G:)E*;?38<@E9(/*A@.$85(9!6.54D=;B-+/H8"?H0;&F?,>,)%?E<@!?"+($5H,G.%%G4CCC4F=6B%>92<=)#;?9,#+H,<A1A1&##A<&/A+H<-4D>?%9?$*$25"-2B3*:(EGE8(%&250CG:;B6#>*?91<:8)E./<(&A".B3!G$BD&?E?)'(.@.0;@76F#/?6DE%+"!#,(51B
@r5480
GATAANTGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGG
+
A+88H4"-H33%@G*AH/6G15&%E>,C$76E9/"048)66<D>9$G3;/5)#$$*FC)>)CEA1&7)G,,."6E@;>(G2+$>E,1(11CHA<2;44B2>FH:"41">F*7,@G',G4;*=8!D;DB+',#3>F218C2$@3'8FD5C+0:"H0H$D#A$0=1!4"<6),>8A%H!=8"><!-*@D4'D;*>@"F,FE@+';6?<""9,+/H=8+.$4"
@r5481
TAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCA
+
?!:/A*@:(7GCFAG9%</9!*,(4(+A>6##F@AC<$*G!6
@r5482
GTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACNCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATT
+
GB?D#<88!H-1*@<"@D>(*%',/?:)A.,/D?F=)%H5E9/65C4;C&2&:3G.&H=):%<080=1E-98#4,2="',/&=)%&%,*:G6E@?'9'11$7#E=H
@r5483
TACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCA
+
A'>4?+&%,;=C.:+9D?"$%F<F(042+*A=#E(G'48*:&5=7"BG(6/9@),5%E/&DA6'F7@G0$
@r5484
CCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATA
+
$+>&22'0=EEB2CAE;8F)2C3B.#-23$?=.F;5%B;"6E1"+-1A">HE:8$5A-,&303>:%A=#)->(!G>@2>9>(34*A,E@0;D61@<30>9B/F2*+/*E#D@?GE=*$4<
@r5485
AACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTANCGCTGATGGGATTCACACCGACTCATTTAAGCCTG
+
/G)#'6()'"83(.:;84:&5H!3.5$=FG@#<#.B>E<7HF@G7B")-@DG:H&+D-@GF3G270EG04'4'G/,A6:45E:<A69
@r5486
CGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGNCGCTGGNGCAGCGTCGGCACCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGTTGGGGGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACC
+
0*B+*,;+.91!"=B,:)?;A81D;F>*+2A7!3()08;)C4-2$,864-(B-?!G!"+9?D)7=729#.,)-A'?#1:?DHC>6#B?57F2)A,.GG)95D?40)7'>"1?.$9>8G#8:B4,=D;$?3&/#*40GGH=<8$./":240057+)11)@;;E.C5C)7;0GC$=9;0:+/<0=42'<CD)7$%H*4*+%/,
@r5487
CNGTGCATGCCACTGTTGCCAATGACCTGCCTNGGAATTGGT
+
&#:1$*/-160D*193/H2:&CBF86#<6>@(,@G>*3-/>(
@r5488
TGANNNNNCGNNNNNGAGTTTNCTNNNTNTTTTNNGCGNNACNTGNNTGCGNNNNTTAGNCAANNTTCCTCNNCAGTCNANNANGNTCTNTNGNNNNCCTNNNNNACNANNGTNTNNCCNNNNNANNCTNNNAGNTNNNANNTNNCAGANCCNTNAANAATGGNTNNGNNTTNNCATCACNNTCCGGNNGNNNNCNNCNNCNNTAGNNNNNNNTGANNNNTGGNNACCATNGANNNNTANNANNGNTCGNANNNACCCNAATNGNNNTNGGNNCGCGCCAANNNANNC
+
$!$"!$!!$"$!#!""!##"$""!!!$#!"##$#""###""#!""#!###"!#!#"$#"$"$!##$"$##$"!$!!$!$"$!#"$"$"$##!$!!###!#!!#"!!$#$!!"$#$!!$$$!!$"#$!""$!"$"!$"!#!!!$!#$$""#""$"$##!#!$$"!#"!#$!"$!#"$"##$!!"###!""#!$##$$#$"!$!$""#!!$!"!!$$$$!"##"#!#$!"$"$###!!$$"#"$"!!##!$##!$!"!!"#!#$""$$"#$$""!"#""$$"!#!$$!#!
@r5489
GCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTNTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCCGAAACTGAGNGACGGCTGGTATCAGGT
+
A1E5D&0/!1$B@H9FD>(./7->(2*5,.+B=%2=:3(-1.@7=(D'#(##$#()7)C>5:4F)320A5"43&$/C%'<!CA8(</82D-2??(1+F,:$%=<&%>'5<=FH$D:?-7'-8+(!3%352#=>
@r5490
AATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAAGTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTT
+
H=>A#G/6+@&'G?8'!C28%=359!:D);0C4G%-:;@F99E;;01%C-!B8DC6#;//28A#92D+20(/?1,@'&+F')B?&"9EB#->*478@A8E):311%CC0"9<$?#19":,#>,@E5DF5H=1$?+97-@4:/)=C>>E?E@#.B?A-6F)9(5?&1(22388%!%%%>:/'76#9DB9,/-#"E+&74F+--3<,BD>/2H+E0A,:>,7G!'*=&/*"!E<&-HC2@8H0./1;)72.C="@*"0G*&+88H6,3'=G&<&A1*48H>*;,?>(+(7'&2@B$=4$@:$F6E=>3CG>CH6-
@r5491
GAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACNCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGNTTCGGGCTCACCATCCGGAACTGTGTCCGGAAA
+
#+#%*#'*%"&(((+!('&+(*++&''!%*+#&$#(!(!"%!**"$!""$%#+$*(($"(%*$))"#!+!%(!+#%(%*++')!)!)+%"%$$)!+$*!$+'!*"*'(!((+&$$!%*(")(#)$$!$"$%*)"+#*%%%##&)$'()&%%%**(!+*$**$#&'+"#%"#!)%*!$!&!+'&%%$+
@r5492
ATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTACCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCACACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGNTTTACTGCGAAAGTTTGTTAATNGAAAGGNAGCCGCCAAAGTTG
+
*+,(AE2:E(?8GE/!*+<=%.C$$"0,&B3)G6<+9/%9)<G8;F="=$8F8FH:G:5!-'G*8%%!A=3<9D&DE)F1"=E"@A78/4)H7)88&:1.8:>)GE8+*F,,2(C%D<%17=+@:6B;-';$<-AH*&;!?CH)67@-21$#39$+9>;#+9A=-C:9)E7CB8<?4:A.*FDH!
@r5493
TGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGNATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCNCGTCTGCCGTACT
+
:B0/<2%A<898>##A1H$-D'2'1$$$'G+!$)">HB?(!<-FFG3#"C3%1;0&+(G?(%7>*.9?3((C5<,<@9.5B829G14@B7=78!D6%5)2(G,>F3G5-(,-63G6H;;/<(@BA.>E-A2');38H09(32'-;"6?33!5C,D?>8(816<ECE.C
@r5494
AATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGANGACTGGGGATTTG
+
,&02!'<<G7F9B/7>.$<+2*:D<F#44.8.6#5H&@>E->F%&3%D%0A0.2''/!85@;
@r5495
AGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGGTTTTATGCGACNTACCGCAGCAANAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCT
+
D++:5?0D$37C)E#&=+7E<#?A>5!5!3.<":F3(5A)(!%B:?A036"*#9":,&<4.9!/"BD:C1-<'+:DE<-A4&>5EDA:?@@99,)=),@#)C4:9H%,C639D6(D6=@A>&$#1.,(1-4%3?.D=?B4G*5(:+?8;#B03G59*%B">=,#5G*".)%:2E?;"E
@r5496
ACATGCCGAACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAANACCGCACTCAGGCGGCCTTGATAGTCANATCATCTGAATCAAATATTCCTGATGTANCGATATCGGTAATTCTTATTCCTTCGATACCATCCATTGGAGGC
+
&0A;!GG245@#1,(G,>G#(3%C+&17A%5+89(;.F/0FG2/4?(@F=*(&6::.1%;19%@$HG@A>E-%D5BG?AG>A#7+H&?85F=$'-B6&(82063-'0&=;%CD1%::!0/=2C;C3:A!@0+9%4"-%AF%7HA#9#:&)5+-,%"FHA5F-$AACHE;D++;$DF*."499?@;/<8//4C=>221
@r5497
TAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCG
+
#'%+*%%))*$#%$"!(&(&##*"&)(&+%#((($!'+(%)"%(%++'#)'
@r5498
GTTTACGGCTTNTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTC
+
$<#-:<H#-&2'B@.G,F/A(5)>6>7G"A=,=C"950?>F#)9?H-1*7CG17<5&7,>#0?:E52":.2=8E<G.(37'@28@7"C$<B5B?>@/?,B='4DE?%#*
@r5499
CCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGNCGGTGAAA
+
B3$@)"',:=D!;?EA>20)4F9@8(/>A#5HF#=>#8EE=,*>16$!49G,G:EE#6G#&F5(-#235,4+1'DE3&#4'E;E<C2)=6$@EF/$;:5>2%#:"92*")
@r5500
AAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATG
+
(6+E?F)($&'.@2&':?4)++6HC0)5BF(&>%D=9',)%(*/%@&0AD(@$/HFEAD*D';58AC&6:9+7GG8&@A'24*5B=&*(1>(,8DE70602:&G#;2A#2?4&B9".13=8;H2(B(?2$?9B#("@((A44
@r5501
ATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTN
+
DG!@'8@97A+C;5=E;$6AD'/.58!9#-/2-?:(5GB785?F.,
@r5502
ACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAG
+
>0;8;!<(@/E>E7-32#F1$C+'D$/5AEG,4'-6>0D,F@(C+/'H6$5>&:$*C;+G!7&7?)/+!>;/-:!4989D.E?6+(E-)/##G15H35%D%,%4>8#0(7F"667C<@58!,+-*4916":()))C1?F@(D!,ADB"/!(,D13(<A
@r5503
ACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGNTG
+
C??,0>D/(?7*A%(8'H?3/!;G#>C*D+!7(,'E9+#+4%A40@0!/0%6"$)19:)#('%--$*-0+#/7%+)&#B)
@r5504
GGAGTGACTGTCACCGCAAGNGCGNCNAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGA
+
ECC5?HC3-F<'9*/1+%!>F$801"=3=="+F8$5C>(<.!:#GH8/5<.=<#B8/B2&=,$0A/EB)*F">,&0"A=H>?8,644#?/8562,'@?!%
@r5505
CCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCG
+
>2A@+@@'=C91+#2-A4.39%#8G#2$&41#'-<A+!A<?@D2;,>H:GC.8>=/63F=1/#!5=0480;B))C%(B5&(-5H+
@r5506
NNCTGAACTGTTTTCGGGCCGACCACATCCGATCTGACNGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGCTGAGGGGAANCACCAAAGACGATGTTATGCATATGCATTTCATCGGNCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGGTNTAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGGTGCCAA
+
#('#'+&'#'%$*!*)&$'&$+!&&"&"$**))#%***%("'('!)!!"*!''#"*!+&(!'"'!)"+"%%&#)#""!'%%*''+""%*"&'(*!***$$'"#%&+*%"&*!))*##*"(!')%+%%*)&'))$&)''))$'$"++++)%*%!!$('')+()$)#*)*!"!((*+'"(!)"+"#$)**#!!!&#"('&))&#&)"'(*)+(+#+()$)*'*)!(*+%'"!!(%()+&!$!"!%'"(**%)(&)+%%%(%$)%$%$%&"%&+*!$&(&#&""(($+")*%*++'&$&$#&
@r5507
NGCNTTCACCGCCGGNGTGNNGGCNGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTNCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCNC
+
%)$!&**')$")*'"##$%!$%$'#"+"'')!#))'((+#%'&*$#*!&+*$("*'(*&&#&!$)'%((*#!)'$!'(%!)''&(!#$)!"%*"%*&+#&!()"%"!'!&"'&!$)""+)"$$
@r5508
AACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATT
+
9?)DB6'-:8,<#/%-)D:+9GA21"0!!0244!?9D0"?5>GGB7C"</EHF88<?/!1;C'15$;G29/13-,A%::D>;++A*+8//@5*-68A
@r5509
TTTACCTGTCATCANGTCAAGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAA
+
E6&D>>,9"(?-763D'22F0<H?<0D61A:#8>/:<-*24H=H,%?A,CE0+70'7-!E5D6+A+).=0B")12=B(=8-=4&-%$*;%E=7
@r5510
ATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGNTCTTGTCGGTTACNCCC
+
=FB?5<2F60?D%23FF=75:.58)$<:<$H6-<EC";E@5H6:1;"&&2@$=";%+91H)=$"#<A;?!28
@r5511
TTNACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAGTTACAGC
+
)$#+!)'#%&+)(+'""&%#!""#!!%$)#%%##))*&"*$")&&!&'&%"!!))+(%'(("&(('))($+$
@r5512
TATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCAT
+
+?=&H>1298'HH">:30;=>:H>0:E1G+8CA%&5>";H3;2CD=5GE?%>F?H!0B0!8!H9D<,@E
@r5513
ACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGA
+
CC%>=&?*%(H>5!:).5//9*)&>7218#8)'*#%;A)*67960A3=)F7D
@r5514
NNNTTGCTAAANNNCNGAANTGNGACNANATGACGTTCTCAGTAAA
+
$#$$!$&($*!")%'"'%'&#($%!$"#%'+&")&%!!(!#)#*%&
@r5515
CNAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTAC
+
,7-#3#4A*",,66G.0F<2-((8@DB*6(,77/=@G#-3<9,>;61>!.=?":?-=4#'"G(B0D2GC7,F4@1H*=;325/(;-;9"?>
@r5516
CACAACCGGGGACGCTGANTGATTTTCTTTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGNCGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTG
+
A*/):D':%H;1@2H%85,$>/#5&(A8G3")E:?A26F05(A3F=88/3C5#0E?;*<<''BB-B%C"!!9/6)".5"86;%CE%"(2E$874#D=/;(64+FAD#(4C=F(,-61D';)768G+/H(&5H?G:7CAG5A,7A7%#.$+#3'.1$)+;4$B#+?:+)E)??!;
@r5517
GACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACNGGCAAGCA
+
2FE65G<%:0$?E$DB8'G3-81D&*-F9/(:,-7:!9#F#E3;%4@G,>B&/436H$>&A),;6
@r5518
GTCAAGAATTCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTCGAT
+
(D:"(;?*!<(7CF=:,%E(D:A6)%<":!-)!9*'3*%C</7G5!51E)6@*ED/69,$B
@r5519
TGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCTGTGTNTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGA
+
2A,':C9F$A*>:5>6$(+&CFED;)''4G?D;+C*,CH?$3B?3@2;4DC:%),1#<60(?>;$"=84DG6/C"&$ED?27"A1H+3;(H,D.D*1G3</-,F:-?D0"2D6?#
@r5520
CGCTGACGTAATATCCCAGCGCCGCACCGATGTCACTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTT
+
9;-<547';4&@6E,+,E>&5*'A,!78D#B!),F5+8@399+'6B'06>7=$=<E06*0>:1)?;A&5.DH5)!3=F49?.
@r5521
TTTATNTCACGCACACGGGGGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCACCCCGCCGGGCGTGTCCATATCGA
+
5.:.G4!>!:.?+=<D?0E+:%7-2F<%$49'7*:#+E#E,*9+4;A(7*=5G)6H:>D*18'#7A$=*==+F*G"A6?
@r5522
TAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGNCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCNCGATGCCCAGA
+
5+'"9''G0/219;.)#/%.E-!76+7@EH?8!.'<G7/106@E=4'B"%!,7C4*<$(A.<*169;=0)HFB"A$#9<!3<F!G073$3%4;)/A=+'+G9"H2E;)''3HC6E+".F!>7D+9;C=EH((*>1-*3+297>A=?#1@81"<.E
@r5523
CCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAA
+
?!.!<5>E57/9//A:<-:C'D3,<"/!7#(6A"4$A,F&.9/-'D4'-
@r5524
ATGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGNCCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGC
+
):?C/CE#*G8)B=H(A33D.;&#,C!!85.//G?!5C.C*?%5'E;0,=;(67,!0!5;%#3<>*5E'<')(*96(D$A%F=A,D2G-4=&6&+H?G"(2#<;3#-&1C?
@r5525
AGATGGTATTAGTGACCTGTAACAGAGCATGAGCGCAAGGTGATTTTTG
+
=2F?8'B1FF+D25&:>&3,#6,FA@GFH,/)DA?>?(E:=A3HFE&(*
@r5526
CGCGNTTGATTTCCACGGATAAGACTCCGCATGCGGATACAG
+
:+@"0*1+A4=9.=:D&/>"%%?3,G2<&&D3A-'3G$>E@6
@r5527
TAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTANTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGAT
+
B/,/0F-&0E!'+GG@77AE>:D)0!".A/.BDB0$%D'5B((%G)&)E&E#>5-AG#.B,0?+""2*?078D19+"3?74$180-'(#=1HBC(C1"2?&(+6483;:5!!'&G?@*#7'C,3(($H'A'(/=5@@+"/%1%@D%.HGH"AG?'#,)->#>,2%4==G"?
@r5528
CATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGC
+
&BB1A"6CH>C&A*,H:9E6':+87@=CH-.2A";$1&E;B0;>.8
@r5529
CATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACG
+
H#;;+C'>$110:4'?8(,"D8@+>%'3*,2&7F.<&E2F0H#F%D@6A
@r5530
TTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAACCATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTNACAGGGGAATGGAATGGAGAGCCATTCAACA
+
$F=(,)@&'./FD8/:4@E,&"21-*;/%'9&=8&!3;!28=.35"F4;7"3G(G017&-%>&H$C2=760?,+8!-.!=E,?%?CDF/4"3<#%:E5=3#866)FF>!D%A7?@B"'$5D*F'B,%&F".7.,'C.2?+!)CG%#:<G06"?"#("H;,<9B-&20/,5G9%64(ED:106@8(*4A*-9F@$45;?
@r5531
AGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATNTTTCACCATGCTCA
+
E>..*@&0888C05+8ED)14<C6+.!1*.(.2E>66-/,EEG())6E3)=<;3)7@$)81D""&6D/(F50+?D-@>DH-'$;::!>:9$?.@!9-&+=4!GE&F!A1
@r5532
TTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTAC
+
DB*A/"D-C)52G(A:2#)-9DD;*;5*+G(8;0A$A,*C#$%<'D-,-B.AH;2,?->51>"=H.),.<AH!(3
@r5533
GGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGC
+
!*&F>8:-1-"(,E,5(4$@9G;B:3+;%@6-E6>$9<?G"D07H%B9DD
@r5534
CANNNANGACGTAGNTGNTNTCCTNCNTNTAANCNGNCTNCNGNTAGACGGNGNNNCANCNTATANANTTCNNNNCTGNTNCACNTACCNGNGTANNNNTNNNTNCGGNTNTTNTNCNGCANNTCNNNCATNNCANCGNANNNNNATNNACGCCNNCACNNANCTANNNNCNCNCAGGATNNCNCCNNTNNCNGANNGGNNNNNNNNNTNNNTCANNNTCNNNGNNNNNNANNTNGNNATCNNTNNGNNGNNCTGAGNCNACNTNNNCNGNNGACNNTCNATNAGCTTANNCNGNTCCANCNGTTTNTNNGNCGCNNNNTNTGCNCGAACNTNANNNNNNTACNCGGNTANATAANCGTTNATNNNCGNNGCGNNATNNTCCNGTNNCNNNNTCNNTCNNCGCNNNNANNNNNCTGNNATNNNNCNAGANNTTCNGTNNNCNCNGNNANANTNNANCNNCNNNNNCCNGNNATGATNANNCTNGANNNANTCAN
+
#"""#"!#"#!#$$!"$#$!$$$$"!"###"!!#"#"#"###"!"""$"!$!$""$"""!!"#$$#$!$"$"#!!$$#$$"#$#$##!$!#$#!"$$!$$$$!$"#"##$!$#$##"!!!$#$"#$""$$#""#$!#$""!!!"!!!#!#"$#$!"!$#$""!$$##!!$$!$!#"#!$$#"!!$$!!"!"#"$$"!##!$#!!#!!!#!$#""#!"$$$"!$##"!!!$$#""!"#!#!"""$"#$!$!""""$!"#"!"$!#!""#!$#!$"!$!""$!$##"$#$!!$$#$#"$#"##!#!"$##!""""$#!!"#!$$#$$#"$!"!#$##!!$$!##$##"""$"$"#""!#$$!!$##!!$$$!!"#!#!!#"""#"#$"#$!!!!##$$$$"!"#$!##"$$#""!$!!!#$#""#!$!$#$"!!#$####!##!$#$!$""#$##!"####$!""!""#!##!!#$$"#$#!#$!!""##!!"##!
@r5535
ACCTTCCCGAATCATCATGGTAAACGTGCGTTTNCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAA
+
C+<"5,A(;;F164/)(:*+*D:)>>%1E6B:-%9!94$5?;<&,.830>&C8<HH2D,1A(.*/8(>#'%-.-@)D#;FB(*#D;*-:0*<'@24><8F::#F
@r5536
TTTCCACTTTTCATTTAATAGAAAAAGAGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGNTAATTCTAT
+
@62;9/31+$<';>.9H"?>>+'>/43@0'7/-<F""*H<'4<>8='4:GF')%A1@(>F(C>1*;!.-5&"#3H0.0HG(
@r5537
CCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGC
+
7#@.;=:5E!<#:51;E,4H..E*29#+*0,<;"'8>EF+9::?!BEC(8%#*=6'1@B29A::=5%C0=5
@r5538
NGCCGGTGCCCCCTNCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCNTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCNGTTCT
+
$(E.'DE64"*?H%F1G!&4,#.9+>?GD%0904>H#;=.ADC@(%180#&>06;7=76?C71,<>1?83D):8,C-G)B/1:<5*%B,<D944(*2&$%6<<!"!+C"%1'0G8"H7*,)>4@1'%!2398C8$+
@r5539
TAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCA
+
E8#H!H=>EDHHE1#&/F">+6:&HG0DD#H$!73.1<)@'
@r5540
GAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAANAGGACAAAA
+
=4H),.';%=42.(2B)B+5E)@(5/G"<>(=?:6C*7F):-6=G-C@%,C:82*<"28<$9#)61"
@r5541
CTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAAT
+
3'H2-74<H9*CB%$A>:%A;215B0+#(2(?&*A&';(<32$%)>?6'/?1C-<(!47/"%1(&)B,.E!-A@'C<>6'9C2@H/C@4?E';*).45C"2D2,#%*67(.,F9+,#F*:B<3';B4'-AE!174!
@r5542
TCATAGGACGTTTCTATAAGATGCTTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTT
+
G.G,8HE6D:+=1B0<F,/HG3#=+'(7>$A14.05;49D,H7<A0A##'A<-?7'-6$F$GE)7BB8/
@r5543
TGNTGGTNNCCGCACCATCCTNTTCNTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGNTGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTC
+
)'#&*(*!"($(%)!#**(#$*)))+!')*""#$&#+"('%&'&$#+)!&*&&)*!**!")!((%**&""")!(&$"$'$!$&"'!$)"&%)%%+##+##+"*'&('%%)*#''*#'$!&!'
@r5544
CGTGACCGATGACCATCCTTTTGAACGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGACGTAAGCGTACTGT
+
+&&&%+%(%)$+)&#%)'*$++#(%')""+$()%$%'+%'+")!%&(&"#*($('&"'$)++))#!&!'%!&*(%
@r5545
CCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGANATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGG
+
G>2%"B0"=*@)3G$1D)60!7"B:0$G&+=,F6B5D/8(1,DG??15DGH0.?-/#F86.FF9<:''@#C,5?%BE(-?G:42!$B<5!E!E@EG9;="2:5-
@r5546
GATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGC
+
3-'A%<.,?4@*H:=/.1A1<?;DD(E8C21(,*".G-5?"6!>"710)%B:D<F&+*?2+;6!89A2G&"D6&&$!;2(.@(5D#;*:H'@H!5"4$=8%'(08#'!B>@H)B?8%!?$,85E'(H);-1!?AA<%/4D4F,*B%>F439C@!*H11&H.)6D$::8-@B%1%14@>BHE%=D
@r5547
AACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTATGCCATCAC
+
3*<-"%?:&009.?"CGH;8)BE<0B48":*56,'.*.!C59%@?81>AG!4CFGD>,E&02DE*BD!(<,6%=4H'49
@r5548
TTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGNTAAAAGATTACGAA
+
++(#*#)(!&)#'#$+(&$""%"&!!*%%&)$!%'!#((!&(%!(!%&$%'*"$'!+)#!*+&"+*#%""*)&+'%"&*&#'"+%"+')($+#*!"()%!)$&)))"*+(*!()+*()!!+*&)$#**&!!""(%#%*&)
@r5549
TCGTCTTCGCGCTGGTTTAGCCATCNTCTTCTTCCNCGTNCATCGAGCTNTTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCANCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTT
+
8*"&')%1,H&((C&46A0/H3'1=7>,@*38,5*B=61!@5A4(+H#*?=:;@,8,)@+/:'D>6:G),F8,"-B(<31('B'/+86>%+CHH9"9H0H.%0$%.9CDH2?//:E6,859785?2.@G!8*;20;-&.,7>5(/(-,<%H=,#<//H))6!/G,1)&*1E<>&C):D&7D8577FC>''-F)5G
@r5550
TAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCANCCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGNAGGAATATACC
+
!#=D0,(.#@@#==%0H+DGF?<--B6?C?6<4?'(D71F(.AE)<-9F2B930?:!&:-=E+-(#=3G/)G0D=:92/./CGH-D.>C"&)"/
@r5551
CGACGAAACGCTGGGAGCTGTGTGGCCAGTGGCCGGATGGCTTCAGCCCCCGTTTTCAC
+
!+H;B:HDA3-/E$#/:.BA9,F?*.6>8,35<;71=)&*%9,9+/E8;3/&?(>0HD>
@r5552
CTCTGTAACANACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCT
+
0#,0/%$@@:-5G14.&AF!+>*.A&&/+(&E$3>%'"G.BG9#?G;;*-(,8CC@#@8;
@r5553
CTTTGAAGGAACGGAANAGCGCNCAGCCTTTCGGATCGAACACGATGATATTCACCACNCCGCTGGCGTTCAGCGC
+
0?5C6'4$G3BC?G:!AHCC=3;=0/G*!9?"34?,HH@1)!A*"6%&.!>*93-3332CH+$;;&@-306*H4:4
@r5554
TTTCTNTCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTT
+
BD(8@4&1D,):!07,B8=9%F6%5519#2+23@AB@+B99;4"?F&%#:>0.!4)8#/:4&$'?;#(
@r5555
ACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACACCACGCGCATTTCCCCGTACAGAACAGGCTGCACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCANACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACA
+
C,$&GG))+!%G2F(/F5C"%$3'"H@;4E<6(CG>AEEG:H).DF9+?-H701B%"%)<-/;<)D(4-&8!G:3'*1/=?#-%.AF6&-@>/;D',8AC*<905(%0B=(7B@2+/8:?&+2=4B&5D?"2C/21,(*5$+$$38?EG1-FA6.!3#=/B8*/&91B@A-GF4;2741FE52=*D>&&CH=@FC2-C:7$=A::>-0<2+.=>A2E33!:3846CA.'A2*G+51=B-67/E%:<,CB4""0H-"2?B1G$>'.'::"3B2?/7;D5H!5A)C-F9AG,-:F<E06?A8-.=:AD;C'=H>A%,FA-9B')C%.F=D*6G
@r5556
GCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCC
+
;$#6&1A822$;G=H47E$=:B)F<;D/?1)6/928+GC"=E
@r5557
ACTTGAAGATATTAAGAACAGCCTCGCAGATNACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGC
+
-3A?'#E?+9GH8"!:$+(8)"(96(-2-4F1&6!='.23"6<DB,=5!4?>,5'00=4H7'<37,,G;&=5,
@r5558
CAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTA
+
$39?(G!E;12@<81>*F/!.7:D!,;5F4#30F28BG/(;(30;.>@'BC#;&+&1&&7E5A:D!+9!*@)G3!4)3?$GCD9C7$H+88&'2.!+8%(>>H:82:8D,#G0G:<*;:/E,./1,:$&.47D.*D<BF;H+CC7B5)D<:GE&>7DF%(C'('+:@),4H9--9D*:<+0;CH8,/,A!&BH019=F+G5AA?1-3(9=$#''0?#
@r5559
NTNAGCCCNNTGCTCGAGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCTAGCGACG
+
%$"#%''&$%$)$'!)"$+")(#""")&)*"$$+#)*$+"+"")!""*'#*$')*%&($)$*'&*(&"!++")!)*#!&"&$(+!)#"!)%&&
@r5560
TNNGNAGNNNNNCCNNGGNCNGACNNTGNTNNNTTTTATNTGC
+
$!"$!"!!"!"#!"!!!$"$!#"!""$!#$#$$####"##$"!
@r5561
NTANGCAATACGCTGACTCCCATCCGAGATAAAAACTTCGTAATACTCNCGCTGCTNGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTNCTGGTC
+
'*"!%+&('$$+$+**)#(*%#&*(&))'"")%)+'%)"&%)##%"*&!'*++))(&&%"%)"!!'+)*#*$+%+&&$(!#($#$#%*&$&$"(*#!%&$&+&')'$%&"'!+&'%(''($')*+'*#!+%*$%)
@r5562
TGCGCANTGACTCTNCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGC
+
"#'(#)")'''')%+"+'$'*+"+&*("#!*')*$"')('&!&")%%*!#&$$#"+&*+*($))%+!'("%("+&&%!%''"+&"#')#$+$*+$!'!"&)$+(!'"(&'$%"*'!)$#!(+)"'(%!"*$%&&&'#(++&!!%%'%('!''""'$!(+&"($!$!**+(#+*'&+'&+!))"*+*&%%#)+&&#%&#(""!+!'*"'#$"%$()()'+"$*#%+)+()''*
@r5563
AACACGCATCTTATAGAAACGTCCTATGAGAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATNCATTACTATTTACTGAGAGCATTCAGAACACTANACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCT
+
*?12.&AC9)99F45:>6=75'#1%C!"89%(A=1=+6G?(1E:B""%+A6*:#1,(?,@<@=+)3-E0<'>>;A52)6!;/GH&0("$11>->#;GCB+CD&!C;$E);2(=B!8EC==",!-9"!&<AC5"H+=)0-&>(D7;06G@),,<&209EB8&@>'G>;E2,*<"(;&3&1$E54,-#$=G#+?:"86#@!$)&#E+?<8+.'"<?,<;C"E98C
@r5564
CGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATA
+
,&?H)1%":D=.%B"C8216&@B0EA;846@;!6!/21B,C!/E65
@r5565
CAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTA
+
-&4EE;"#<F4:/F':'/!)2B,4)C;1.D(:(,(H9H-%'
@r5566
CCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGAT
+
'@('2&D:A0!.F&)8*/,E-*4@/F(((/5!FH5GG*?+$8,/G1
@r5567
CGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACG
+
,@3<)H?A,=G=F+F<EBG:0:;D/B0-%$!0F@"*!@((-8'D'61(A7#;A78#-$*9'G81!+7
@r5568
TNGNCNTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGAC
+
(!&$(()#+()##&&'!+&%+#%#"#))!)%&$'+&'"&"#(#'#')!)
@r5569
NGATTTTNNNTNCTGNNTNCTGCCCGATGCGGCTAATCAGTACGACGCGATACGGAACGAGA
+
#*($%##"&''%%'&"&$#%)$)*+%%$$+*"&')'++()#%$+%#%%'*&)('(#!'+%)$
@r5570
CGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCNGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATNTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGNAAGCATAAGCACACANAATATGAAGCCCGCTGNCAGAAAAATGCA
+
)5(!+0BC8!00E;8F3!B6?/@2/+''+/+=3"/,"==*F4.24(70H0,07G<'3E3C-5F/&%D:AH,H*930D2&CF$)-@D9D>*$/H#)99)17G#A$92?9/*$%-?+<71?@)#"F<2@6(8F$$C.,(H>EA/7265?*E:9G!862(;9H@H,CGBF;A@98E83,&EDH;/:-8>>%:.>&AD"D&!D*B;@#-E!+FC45*;!0'>1-,13>332875(#0=:H=G=/87&+=%*0(6
@r5571
GTAAGACGGAAATCACTCCCGGNTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATA
+
='5:3B.G@9555:257B+*D+/D),7H,+<0!G1'G#A3#1G:=.*2C:>>B+1/&&C+."93;?:"%1;@
@r5572
ATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCNACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGA
+
<4(+/6%.'5/2"GC16)0.?F4.+"9.C!(,05G+5,)(!%E+#7(E>.0$7>1#E<=2HA7;>;D#A;E)>DD7H(9"@0FBF3"'E,&9(-H&0.17$
@r5573
CTGGTTTTGCGCTTACCCCAACCAACAAGGGATTTGCTGCTTTC
+
=8G2$"?&9&@)>D!":/B5:C0,3H@G;A3+8==C98$F!AHC
@r5574
TGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATC
+
(>>0)D01C%19&#'B(7/;<H99>7%;%3!(@E36@0&%2/<GD?)$G2C-!8>%$C%@("C<8.9)A7FD!%6B=?!&H@5*!E.3?$)%4;D9%:CG?&DE40.
@r5575
NTATGGCTGCATTCAGGATGCGGACGCACAGCGNGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGNGTGACCACCGGCGATCCGCCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGC
+
+!93((111&2%?1/=E=A25*!H*GD/2E!#7).AA'-!8H3"+5+?(0==.-3ED/@.*=7&C7>5,E.H'$/(E+8;*'%*($3H&91@9D8"9<*D4(!")1?FBA;30.?2$(AD!A0HEF7)G(#BFC(C='
@r5576
ATGCGCCGCCTGAACCANCAGGCNATATCTGCCACTCATTGTTGTG
+
+#!"$!*+!!+"(#($$&!%('#&)"(''))&!'!#%#(+(("+'%
@r5577
NAGACGNAAACATGCCACACATGAGGAATACCGATTNTCTCATTAACATATTCAGGCCAG
+
"*'+!$$'%%"#%*'*#)&*')&)$))%+#%!($&$$)*()$+&(!)%(!"')'$'"!&'
@r5578
NACNNCNNNGNANACANNNNNNNTNCGNTCNGNGAGTNTCNNNACANGCNTANGCANTGCNTATNNANNNTCNNANCNNANNAGNNTANNNGAANNGCNNNACTTGNNCAGNNCCNGCTNTNCTANNNAANAAAGCNNNTCAGTNNCGCNNNNNTNNNNCGNNNCGANTNNGTACTNNNNTANNNNNNACANNNCAGNTGANNGCNNTGNNGGATGNAAANTNNCNNNCGANNCATNANTNNGTNGTNANTNATNNNNGCCAANNGNGNNNANCNANNNNCTGNCANNAGCTNNNACNATNNNACNNCNNNNNNTNTTNGNANANANATNTNNNTGCTTATNNNNNANNGCCTNNTNNGTGGANNGNNCNACGTCNGCNTANANCNNNCANNNATNAAAGNACACNNCATNNNGGNNGNTNATNANNC
+
"#"$!$!"$!!$$$##"!!$!$!!$##$$"#"!$$!""###""#$#""$"#!"$""!#!$!#""#""!#$"##$#"$"#$""##""$###$!"!"#$"###$$$#"!##"!!!"#""$"!"""#$!"#!!#$#"#!"!$"####$$$!!#$"!"$!!!$$"!$$"###$#!""#!""""#"!!#"#!"!"#!#$!!!"!$$!!$$""!$$"$"##$#$!$!##"!##!!#!!$"#$##"!!!!!$!""!##$!""#"#$$$#$!$!!#$#""!!##""$$""#!#"!""!#"$$!"$###$"$$#"!!#$$##"$!"#####"!!#"$#""""#$"$$#$$#!!!$"$##!""#!""$$$$#$"!#"!$!!$#"""""#####$##$$"$"!$##"$"##!!$$##$$!$##"$!#!!!!!#$$$!"$
@r5579
TCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCG
+
E5A*8&&8)>(H*;A0D=1@25DE#"0*:G&1:&*+A!>$;"B-2<!<*!!)=.<=()(;CB"-4@/>+.8A4<0225B;?$BF"!6-#4723/G+0'5<4@=+21(,>$7H%98->9(6%-''02,G4
@r5580
GTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCA
+
GD;<-%.8$C,C:81:D&,G9$G4#'9CD$"G$4(:;(#*@@A.A<&GF709,&.5=B<('##C%=;>@&:+?H2#!B2!6:AAC3/&*3)2!-=:8(B11)&)>D<C0F38/?6G%9B>//#98#39*;'*?+=>;2CC8B;7*%%52:&#?@B5,HE$A4%65
@r5581
TTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTNTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGT
+
C%7:G>44/FD0,&/D8&$&7?7/=#.E8!H%,6>3"@.6E$"*C4>HE!&4*B!#9*E2)#5%$H*@02@!-#;=4,-*('6C6%8
@r5582
CGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCANTTTTTCGGG
+
F"<HA765/?G5>D73F%4A?@1:85,!31F7>@<:?($5!F8D*"-&F"'9)23D=2%C5)&,
@r5583
NTTTNTTTTTCGNATAANTGGCTTTAAGGCGACGTGCGTCCTCAA
+
!*'((#"%)('"%''&%$'&"&$+*!$'$*)(%%!'&!)$%("&$
@r5584
AGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGNGATCTGCACGGATG
+
&?0!2>CA(G-*.*35>.+>(;$/9D,3:=.>F/F<B1&@GGB(*E661.9A2.<*"B+;1F4")-/=@B(B4;4>#-4C/5,E"G
@r5585
AGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCNAACG
+
(H-3D)),;=*58#%;&F4F*45C@H.1#C'8DD<8<1.F8D8)@:@A1'2$:*><E*51F5$F320'9>
@r5586
ATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCT
+
98$7:)=0(E()"B"!A';H%+=>B;!3>H*".(5E;'!#EA=4':6/A.==&72F3;)G"85
@r5587
TGNTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTNCTCAGGAGATCAGCACGNCAGACNAAGGGGACGGTGGTCAGGTNGTGGTAATTGGTCGCTGATGCA
+
:6#.?8<<3@H+-<;%DDDH:393/',HF14E@/>#"BD*/,8%?GF>':-HD9<BFF#B%%*>2F;&*#8B&"9=.0?!%:9?F.+87FF%.?A"<$>H*@-+E<@
@r5588
CCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGCCACGGCTGAAATATACCGANGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTAAGGAA
+
34")H,!10/GC1BA#*"&*&6'BCE>=D5$:3!5;@$?/*),1."'-F"&#B%:1<=.1=4$0%9(?=HG&4<+!80C/4-="6$!(A#C$DH5H4->*@G(83@".1'((),8C2&,.9-F.7?3$7H6!$$=6?B&"6!(F?0(6>D)<
@r5589
CAGGAAGCGGTGATGCTGATAGAAGCCGGCCNGAGTACCTNCGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTNCAGCATTTGAATCCGGGCTGCGACAA
+
+)'(*(*$'"$++$+$#$('!#"+'#'"*&(%'+'$!!)**%)%(%*''$$+""%)*#+#$&&!$##!!"&!'&)!''(($&"(#"'#!)*%)#($*(#+&+#$!(*&!'($('%$)%*$'$%&"(!)%*%++'&&*$"*%'&)+#*%$)*!&&!!+++&!!*''''&$)*&*"))%##(
@r5590
CAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGG
+
HH-A*C$2.A;2'@C3>FE@+-;<3?:$:A$5/F4DF6'=<&36-C&F6E0@B
@r5591
ACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACA
+
F#*G.,A&6$;!8/(!7!'5<B5:E>752!,(.4+!DE1*2(-D!"1E
@r5592
GCCATCATCNGGCATCACCACATTACTGCGGTTATAGGTCCA
+
7GG''1A(0".42$"H<!7.3!G.&,$BH#%>/9;B&.F6C:
@r5593
TCGCGGGGGGTTTTCGTTCAGGACTACAANTGCCACACACCACCAAAG
+
:<H&F$8(;,?G*#/"3#&A4(#292A=A%91C.92%#H9!("5,9"+
@r5594
GACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGNTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGC
+
'&7'B#*>.#>0-DEHD<-%G#845<E4!9F4;@B?E>:70,E"2D;:-!$8(1;#@!D$H&;;CFC+H%.)'%.<E>/";D*GH'
@r5595
GATGGGCTANCNGTTTNCCCAANCNNCACGCTGCATGACATGCCACCGGCCATNTTTCAGTTGCTGA
+
#%("))!%()#&)($)"$'*#*#$&#+)"&#)*(&"!)$!!$''("%$+$#"&*#!'(#$"%#(+"$
@r5596
GGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGA
+
="-70=*=08"B*%>-C2''FCC'9+:.DDG2@?DC1E9'7BD4@#*<"!DDB@E8<C.6?A5<*@';>
@r5597
TGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTAGCCCTTTGACGAATACGAGTTTGGAAAGCCNGTTGATCATCAGCAGGTAATCTGGAANCGCNAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAG
+
61A/F+1"F:F$5C-:2B"?$@)4G1+-B6)0G@1!':"=8::1%*2//#,"6.<G7CF)47A&$&,0*'$C*320':16'1$D-AF("1%###@-<(C9DGB'H<F1)E0/,(.86E-#8:G*C#"6A?G<'A#B*5>.===A"'.(9G/=?'7-,'+B*)E/3441#*4%-F%DA3?BB1D=?*.5HDF@@9?A+0#6(!9.)%&'%@<$A(587H;?-+A/F)E?G!1
@r5598
ATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGA
+
9%<!H"03;0*8*220H/+?G90D33<:=/"F%107-C$<($(,!4H!+4'G"#5)189/HF
@r5599
CATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCC
+
<1(/&*=!'"@GG/$)@A#-9$2,CD)$%2H?<7HG)9"15
@r5600
ATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGC
+
E)&7722!<);'C,-D=:-?H-B6'>B+'A)&1&>#3@5H+25*C.@=6D0
@r5601
GTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCANCTCGTGCTGAAGTGGCGGCCTCT
+
9(%8B!B8%50<(0E),8D72C2>!+D**,#!F<@?A!4(6A#*-2-;F%?-A006-G&BD:C
@r5602
AAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTAC
+
)874G%B?2#8=*:*@<+%;(*@;?('=/A%>),@F!#B;:$@0
@r5603
TTACGCAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACNGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTNGTGGTAAGCNCGCCGGAGGGGGAAAGATATTTCCCCTGCNTAAATATCTCCGGTGAGCCGGAGGCTATTNCCGTATGTAGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGAGCTGGTCCANAGCCACCCCG
+
'#)"(+"#)'#)&##'%(*"'''!&%$'"++(*)"+(+&###$(#(*)!*("&#)++%#$""$&!)+(!$'*+(#"!*!'''"(*#&'"+#$'%%+!$")*$'#"$&!!(#"*%$$##"(%%$('+(&&)''$)!*%%*#&&'$!+#(('!%+"$*$!*!"+#')*#*&$$*&%("#*++%!!%!%#*$*''!%)&&+%)'!''&''+)&!''%!!&$'+%$*!')"$!!(&+'+*!(##($(%'")&&*!)%%("!)$+*+)!!#+)$(*$'$'%'%$&*&")&#")()#)+)%%#!+(('&)%'(&*$"!#($)"%!
@r5604
TTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGTTTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTAT
+
-247F04*:=BH!$**-ED@G#<A7.$C@1795C(:781#)8*,'6>"*7!*/7-%+DH0)'?*)0F&?)21%&8G!**/0!,'/=-5:%#8/3>&+
@r5605
GGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAG
+
><C&D2<G'>7;GG7.A@1<@2.=>025+>GGE69(5;($C=1:6<1F%1E',6!1-#"&6B"9G?%7=#7?16?79>B*1F?%'D;?3>)%($6?3B)$7,.8:+3#AH)4/+613@D'4%=%*G)F";C/?6#?'?H878&E7D-0<78=@H+/<E)D<!=/$!!>5&'C<0>";?%>;=1G5A6#40??)<'0-.)%A)H917*$!(->+=?D2*8D%)G@F/1F74ED
@r5606
AAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGA
+
FC/D+?0G63:1#?3?,C=93<)8*2?1H9?G@E5=B!85&$#+D"980EC)CB-='!C/F,373B<"5E6-F@$46(:69=7+29.'#;4".0
@r5607
GNCNGNNNTGCTNNCCGNNCTNATCCTGCGCATCCGGATATTAAACGGGCGCGGCGNCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGT
+
#")"*&'!'$%)($(*(&*$'+%+(!'(**%&+'""($&!+$%*'(*(*&#'"%$&"!$+$#&'*)"*&'!"'(!*$&)%($&*#+!)&"("!"+$#(!
@r5608
ACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAATTAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTT
+
<%H%:0=6!1:G#:3;<&EF#25@%&D,G=)C;C47$&10G>E--6251'D&4&>F8(=:<3*!1&$&$3-G!+;85"7@E8'C)<8%;<9;$B
@r5609
TCGCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACC
+
#$($)#+')%*")%(')"**$#(#)'*(%#'('('#)$'$+"+'"*($)#(+*'$($*)")+#)!'))"*!#$!+$*$"#)')'#$"(%&!#!*""*
@r5610
GGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTC
+
>/F3?E1$,".>+!7;:G@0@7D2/,,<=,#41+854:G85A'&H7<")'/F<;!0-2GCDD2@41)95832FEEA!2F;(95#?C.("*9B+0*:122((?*HH/!$6@E86,)0A(A&C92
@r5611
ATNGNNATCGTTANTGCACTTCCGAGTCACAGGGGAATGGAATGGAGAGCNATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGT
+
*&#&#(*%&"*!)!%+*$&$!&&)#$()!#('*')"$#)+((')&'"+!%%$!&%++$%(!("(!"#!&*!")!#("%%(#)##%"%'")"+$'&##%&!!")##!*'($#*&)))$'$%"*+!!'%"!+)+(#$
@r5612
NCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCNCTTTCAGCACCTGTCNTTTCCTTTCTTTTCAGAG
+
-8:)C5;2;=G)2>*>9.?$.";-0867:=+7H*6C?58!41E@<'AD*)0;6$1@44=(B1';E=0650/C6>*F7!A;#!.585'B=2)@64E-.A74.ABB0"46#A)=&D0G8);1&B&?;!E9');59:7DF$99!H>'-D64<9E/=#45-C?7-F!A=:+35%.5FB/C'4!3/3H,84&'
@r5613
TCTCGGACTGCATCGCTCAATGTTGATCTGACTAACTTGGCTGACGCC
+
)+$&&+!+&$*"'+(++*"%!('#+$&"#)!"$*'*$%!!(+($%%&"
@r5614
GGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCA
+
>8'8HAA35,G*5(.:G3=181>>?=H=);5CG9:,G%61>$</:(!$;(2<E$,,@H88%@;@!<-"EH>F%0E3FA9.;9D6#6=9'(>2=F0'@&(BE@4+"2:>$4?5.2<-5'9
@r5615
TAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGGGGTGATGNGAACACTATGAACAATTGAGTCATAGAACTTCCTTTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATA
+
;0.C5C53'8>E;'(9)2F20'F;9DHF!<4+#D#,38>;4)0D,4??-9F39AEF$?(A@<1H#C!6%1,$)3=8)>":;"F+#BA7&2,;.7/E8G(!H3>+!9-FH.4G'/G?=!C"/'EBC>6EEG$(?;!AE.@9D;?;'2CC;?1=2F$C3873$;&99B:;%;E<+:9;<B/5=22)287<"1<3#=D)BD1
@r5616
TCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCA
+
3#>C3*%/G;7/(*)<AF,4429;2;!$%*/A%&E=*"B3!+4%;1F!)74/((B?4#B0(/@*&9,4$(?,D$,AF=-D#934'.7&B9(
@r5617
NAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGCCCGCAGAAATTTCGGATA
+
!8=:F)=%G4#>-D:;;;0E+9+4A$<)@A97:$<->?-6;"@!>31%7*':6
@r5618
NTNNGNATCNNGNGNATNGNGCNCTCATCCCCTTCGAANNNCATATCTN
+
$$#"##"#$#!$#$!"#$$#"""$#"##$""$$$$##$$"""$$$"$$!
@r5619
TATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCAC
+
D&;B:>47AC-2>*D/>'(93%,:.<CE/#/.G*H>A:F*GF4H:.
@r5620
GTCGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACG
+
2B!<:?8)?58)/F1!B+A-"81>77D8D$G+8,:5B-)1.7:/3%9'@A&A*#F+#0#%41<DEC")6$9DD,>9F+&(ED/5@B?5.H2/)>,?=#130H55D)
@r5621
GCNTCANNCTATTCAGGATNTAGTAGTATGGCCAAATCGATTNGCCGACATNGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGA
+
$&!"#('('+(!%%&(+#&$%+'%()'+$')!'#"&##+*'"!#"+'"'+(%)&#"+&"%$+'%#*#*(&)%+)&("$&%+#*("*'$
@r5622
NNGCNGNNNGNNATTGTGGNATAANCANNGNGGNNNNNNACNGGCNNNTNCTNNCGNNANNNNANTNCGNCGNNNCNNCTANNGTTNNAATNNGCNCNANGANGTCNGCCNACNAANNTCNAANGTGACANNANTGGCNNNNNNGNATNGNAGCCGNNNNNANCNTTNNCNGNNGAGTNNNNNNNNNNNGGCNGNNNAGGGNANNGANCCNANNNNNGNGNAGAGNNNGCNGGCNGNGGCNNCNANTNCNNNTTNC
+
#$$$$""!#$!$!####$!!$$!!"!$$!#$!$"#$$!##$$"!"#$!#"$!#!!$#$""!"#$$#!#$#$#$""$!"#!"$$!!$$""$$$##""#!#"""$#!!##!""""!$""!!$!#!#!!$$"!!$"$$"$#!"!"!!#!"$#"#!#$#$""#$!#$$"$#"$!!"!$##!$"!!"!"$$$"#$!$$#!"!#"!#!!"$#""!"""$!!!"$"#"!$"""!!##$""$$$!$#"#!$#"!$$$"!""""#
@r5623
ATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGAT
+
A(4<<A*.GH-;6++B$GF-GE/*=A-%9(.E1=!F=%/;)E9G(7>1:!%5FG.>-)H47@38472%#A@F@6>9$+0-$.42@;+"?!%G@-DG%5(;F5BFH2526A7$#$3*0@67>-7$>%%1C&,/20;>26:(4F-+38+E,B-#!$:!B7!'&$84=>9C8
@r5624
AAATGGTCGATTCTGCCGACGGGCTACTCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGC
+
A/F,B-83;F/*9<;GHH-"BF#"<3?BE%6H2-@B-&6,<#1E(899F,*D&5?H),+1;=9@8D*$%+#!0<'#&)7!0,''<6?,D%):?@.7$1A-4<8!>D9;&>2E;#"5984<1F8&9#G4034C
@r5625
NTCTTNNCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGAATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGANGAA
+
!*%#)#"(+*%#!$*))())&&%!*$$(#%'$#"(+)"+()+&%"##)(!"('*&#$(%*%**%#"*%($'($('#!+"&&!(%!!%$+#+"%'*$#'$$+"*+(*#+*("'$*$'+!)($!*&'!&+*"&)*+"'!!)'(%*%*()&&""""!+!'"$!%)!"$#&"$"**%()(&"((")'&*)$&((#(&'!!)***"#+**'*!%")))#*'+%%(%#&'%+&++!!
@r5626
NCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTT
+
-&!0&=E?/@-77/;7@+B,.-*8=,)76('D#10@*9F$>E:<A+E*/+274A&
@r5627
TGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCT
+
F/8'@"'4)(C@0.</%0$=4#.:ED$)A!2HA.=!?-D3=-%(96B$(2H"$$8
@r5628
GGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGAAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGTGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGA
+
B/$2$C#>/4A3=2#37@.:(G4/B&G/A0&><$8&<09+?3.*0!/<"6DG#!E==GD=744@1:D?8<;+H<?6>0:;@<E#=9?3?1:<+"D,+;(,>9?=4C0,'1/7:<.67!*<=D5/+/D*,F%(4!4GA+8#%4,<E!7E5DG(9;589G".D<5&#AF;>'>
@r5629
TTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTNTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAA
+
<!B(3;"05&$F03AB=9G3).&>:,*H>6%?HF36D,B$%!<;:5"6B$5C&F79;/FH,G*"06G($1)&GHH:'!!:H'8,95*@4B3$B0$0<)=88H)E=+?5
@r5630
TTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGA
+
/1?(/0$<=5>+6%#8>3&F-$?2=""A+>D4.<.<CB/$#5!$0613E</8)0F0'4B,6-B.<#=7?38(?,G39%E2
@r5631
NTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGC
+
"@7>&$=!A)030!3-41!%:E))#0.2=7)'?6D%0!/+$-("2$H+C?6#H*HH9!*%1=G=H=)CH$,#D5035E&+%3079-A$@
@r5632
GATCGCCCTGNTGCCCCCACGCATTTACCGCCCGGACTGTCAGNCTGTAG
+
400GCCG"D.$6=(#'E.?9F&GA!+3;3D,?7,+4!49$=.EC>"(-0'
@r5633
GTGGTTTCACTGCTGGCGTNTGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTT
+
@)#*E64901'2)=!8;#9D0:;%@%F,-35>-+1E@BB/C-*C=C=3/0$255D2?%(3@/""&6E/8)0
@r5634
GCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAT
+
!"/49%(?<$G)?16&9(6C'@+$+.0H#4*4!";F15/B5B)
@r5635
NTNNNNNGANNNNCNNNAGNNNNTNNANNGGNTANGTCANGNNTNNNNNCATCNNNCCNAGTNANNGATCCNNANNCGGNNGTGCNGNNNGNGGNNNNNNTCCNTNNCNNGGAACNGNNNACNNGNTTNNNNNCTTNTCANTNNCGCCNGNNNGTNNTNCNCANCNTCNNGNNNCNNNNTNCNNCACTNNANANGCCNAT
+
!##!"###$!"!#$!!"#"#$$!""#"!$"#$$#!"$"#"$!#!$$!!"$"##"$"$#"#!!#!$#"$!$$"###!$$$#$"$""!!!""##"#"!!$#!$!#!#"$#"!$$!$$"#$"""!"!!!$$"$"!"$$$!!"$!#"#"$$$"#$!!#"#$!"!#$#$#"#$#""""!#$!$"!"$#$###$"#!!$""#"!$"
@r5636
GGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGNGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGG
+
5H#1F,D.+!-7$7-F2<$+&G%,<8%,5-G4B!&+9@$B9EB,/+-9:31C%#G0,3002*20@!$/8AA='$;!%#C5B2H=D@D;8;#.%AA/0<0B;?9/,A>(8!=B%7:$1/:0-;A6?5.(:#7;'C5#F/@,$$.H?G4G7=E1'G
@r5637
AAACAGAACNGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCA
+
@6()@386E&'8E.713GD*?-)(:F%*B-7'<)),%>*1$3%,>"9F"44-##.9C,99=
@r5638
GCTGATCACCTCCTGCTCCGGATCGGCGTAACTNTTTCCGTTG
+
$0'4:%-@-0<G(?D7F(4)66'<0G?<H<'<C&6C&@,6=H7
@r5639
GGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCAC
+
#?"%C306)@;=?C7'&C0),9H%!G6(B)8<">@168&#,2A"&#4?F*,*B:$B84<!$C,?
@r5640
NTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGANACAGACAGAATC
+
*4+"+DG12:<.>&D#9E4$6&B(%B!@B:,#H>):H/;)':6;$E5'(E@4
@r5641
TTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATT
+
.6<;B0@:H()--8?2)&3$&(C668&%-)9=."=GF(+94F
@r5642
CCGCACCTGAGCAGGCAGGAAAACTTCGANATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCC
+
8:">E;E#)2(@G'E:E/3.FEA0H3C'B,G0.")H>3<F8-*7A+E4C0)=(0F%/#>@'G=&)>;?:.F5/
@r5643
ACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGC
+
4>(*H979!6!8G;,)(H28D5=9:9+%3"E@(:D%:50;;2=D!:
@r5644
GAGNCGCNTNNTGTTNTCANTTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATATAGCACCTCATTACCCTTGCCACCGNCTCGCANAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGC
+
*'"$#%"'*"$!(($'++$#$)$*!%+&%+"+&&""(&+&$&+&$&''&&"'##%$%'(+#%'))!!%()%((*%&%%!$$'*#'&&(&+*"&)")"%%"$'#!(!'')+*"$*$**%!!(&*%+&'!')#"$*"!%+'(&%"%$'+%"%
@r5645
TCCCATCAGCGTTACCGTTNCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTA
+
6:&<C#9=+&#?$$*715(4@146*!!(*>%D:6%0<B7"<,8/*=52H=><!18&==;<7#<0&%0
@r5646
TGGCNNNCNTNNNNNNNNANGNANNGGGCANCCNNNTNCNCTNCNTANNCCANANTANTNNTTTCGCGCANNNNCN
+
!$"$!!#!!""##"$!"!$""!#"!!$""!#$$#"##!$#"$"""#$#"###$$!"$$$!!!##$#$#"#$!"$$"
@r5647
CTNTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATT
+
D!!7+@%.2'*71#('3A/%C:#FD04)";0BC@+"BH;(7#A#C?!4;5+
@r5648
GCGGTAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACC
+
.BA&F>B0<!;)%12FA<FA260.;89$$0'*:D@84(.-A9&#0(F7#E>"55+%-A6/?2D*3:8E<&1':>04'-+F39F606,)DG:2*&<%8)4@726-):';?=/H
@r5649
CGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCTCGTTCCCGGACGAACCTCTGTAACACACTCAGA
+
60*(>$26:.5C+$1:)2(:E!G$*";4;B?),59)21F$D.!,;!=$;D1H%,F*3*,:0HD@=CCEF(<2@$D./+AA*#/6'=$2:)$4)-,A<5:/>-7"/5(7.
@r5650
TTTAGAATGGTTTCATAAGAAAGNTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAA
+
+"!-;3E7>;F0=A:3E3+E/=(C0-3+,?7<)B<4=B-@<:'+$H%:</H37'5>5?.=8)",.$H1A2*GD;!?F6D*:5)D9CD+763,8ABH*8B($.=4
@r5651
ATTGAAGGGGAGCTTTTTGACTCATTGGATATGGTCATTAAGCCANAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGTCATTAGCCTGCGNGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGC
+
;04'=7%=D8>C<$0*CD"@",#*%.E1*=!C+853C#ED+(>(G6%=6B8G&7GC20"*GC%A4B0:9??E>=5>5H0.>+*!-41?</*5$,))*<A<E9$/5):+725!;+6@FGD!2F493H#,18E=CF%F%,%G3'1DF*5;5CG:DG*>>8;>4B4&-G.@B#C,%2'49<D@
@r5652
AGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAG
+
80;&G9CBG,0#;)C$*0.-C-E7=%699)25HC0&@$#4B(6(659A2E9.FG'4
@r5653
CTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAGGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGC
+
%H?<=F?&$6";."$CB'18+<2<A8)?9:?.(+3-/G735%)"F!0(<DA3F4GH&DB/#7):A7?7C@5D%A/B:2$'HBE>510G%>.6#-447@ABFBB@=7HHE"#;H7,D.F?CH1)/@20/1C.'%63%&DC'?7!"D-51>H6!*;.-=G+@A<3@>H7$+)F(<C&
@r5654
ATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTNCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATA
+
/,#'$9"-?D7/<$72?2"8A(A$04DF!/503F-<@+/"*B+9#*<57<A-DGH#A8"6=9)+0*C2")D!@C-:25%+@'A1BC-6,$>%GF9B@*,1/6"-$<F'E?A'%-$F7+?)2$A+6:72#>C<(6!3B9)$6+D+"!30/&#8*73-D?(+AG2':$BA8'!-<-/>)!ED+7C1*GA&:-
@r5655
CCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGNAGTGCAGCGAACTNAGCGC
+
@#.*=!#"5?377=7D<6"F@26#8*EG''4>-+-,44#@%3C36*HAEEH!22.:!?=&D
@r5656
GTNACGGCTGAAATATACCGAAGACGCGCAGAAGGCTTACGAACGGCTGCAGANGCCGCTGG
+
56/>2H=(8'166'9DG!<%66,,(?/90?C"H10%.5C">"G'*3/$4-8-AB03*!</H9
@r5657
CTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATNTCTGGTTGCCCTGCGCCACAAACA
+
>-/1)%;022:<*7'6D:+)G.4.H'<9'B-"?=B$+!(%*AB,'$+$56G7A2&:96<%+.'3="?D#%H"09E#:;((!;1F6.)B%9%0+C)H2B!*@<6,::;$CE25>B"FD>H
@r5658
GTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGC
+
5#G@H@/C%:7<G"'>2,B9++<8')/!32)E)A2>-+,!A&(FC@4
@r5659
GTGAACGAAATCCGTCGCCAGTGGGTTCTGTCTTTTCGGGAAAACGGGATCACCACGANGNAACAGGTGANCG
+
;C;G$#+.&06+#FB.@=>2A9A=A!-A@<&#35/'28-'98A0=&$=>!:+-,#0='@9&%$>!"C<.=!/0
@r5660
TCTCACCGAATGTCTCAATANCCGGACGNATAATATTTATTGCTTCTCTTNACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTNGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATACAACTAATGACTTTTCGCCAACGACATCT
+
1B(7GA7&(-),C"D6(80'(@+?(E-32;G-4(9.>"E3>325@-%>;#+=1'/!*-59!,B1-/)?>1:5+E=H"&H<+&&C94*>4HE*".:<2AH&'22F9E!-+3H3BH0:88$6@.6&:0A@G0E?$6:$5-F6%7B:BE.AHG.#=6<<G#6E,C:G;A%*79!?B(*.>9B:C>.(:E;)6FCD+H975158E"-<%,5+A)<A+9@E$89F12<#9A6.(/2+G@6DG*C?5A3(0
@r5661
GCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGT
+
??BF(0G>&;H3?)G</&7!;@!E:E,!'8F7F.HE%-H!1%66;:9/HE(E/E&%*##>%C2<0*6!'/'(A!38DG>3"-4=
@r5662
CGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTG
+
'>A.;3*>(HFB03=+59/<'+C=;HH;-?0).*30?3&5.2H$'%3F&8)0@6:&-%;:F$(F@2=
@r5663
TCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACNGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAAAAAAACTAATGACTT
+
)727F*(<@?+B613E&-0%A5G>3-7BHG7<.:EE<.:&ABD%5/8/(9+D$2?+H'=5H.C$-9F3'61&+(44(!H+!;$<D'>5;%>1/'-493;*29+#$%8%7H;#9.AD7*E")DAC*+,<?H<D8G2B)2;>.895#;("'!%F8@:(BC6(8E>0-78,F))A*",?2;1%E<%5-''#H&H@*7F?!&#A<>A$+#6?,+1F3HH
@r5664
TTGACGCACTCCCCGCCGNCNCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCC
+
30B!97/.>C?H2,H-G$=;&!1C&?24-A:6$('6#%3G?*"1G+,/E<.!=15:8((6*7A(<+5,:14$A>2GF8*C(*00/3'C%4E<7;C++%&3.H34((/
@r5665
ACGNCCGCANATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACT
+
5G&5E"96$4/B)''C1EE)8E&):E>88"0/(HA+99)31?7'GB0-!F6,('0))
@r5666
ACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAANCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACAC
+
()F=*?!H3<#.D2=G3<5:<"?"$,,.#C-C31==<<!*4&FC"%B5DB1@!A469F1B#%8,FB6AG.D693+*60&.$/$"+'<''6?+2E$/,.18A$!8?BB$8+7:5(&7A:='3:/1A5;/<-
@r5667
NTACANGCCGGATTTAACGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAG
+
#H/2=21A%9A2C%.$F"/+"D2(@%GHH3.&.?,EA!!>(:8"EE3=7-9=5&>CHD,1$*40:&1&-(#'C8)1&5-$2/--,",+D-G0(+:9
@r5668
CAGGCGAGCCNGATGNTTCTGTGCTGGCTGGAAGAGGCCATCGTNCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGNGCCTGGGGGAACTGCGACTGGAGAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGT
+
01/$)/HH@=G3471D6?"+*71'%0$E)H/%'+E,A6H*:H:!-<?HD2F(/15#@&C1,?$EE@GH!&>$(:F-1;;#(?+G&&)A#F93*)#-&2<)56C(3$50)176:G=(AC#1%3HB2!?<<*@))''*-(9+!<%/*E@=.,"#A.@:E-*8"@'(
@r5669
TGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGNGCCNGCAGCG
+
:-7C2.GE;H.)->!+?7.0&"(#4!=G'+)9/*%/+/C>2!BA/@4H,D-)56148
@r5670
CCCCNGTATNGTGGNTTGNGATNACNCTNTGNCATCAGNAAGAATANTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTNAATTGTTCATAGTGTTTACATCACCGCCAA
+
"*#*#(!(!!)#!!#!"%&$&&#*%"$)!'"*##)!&*("#'"+!)!"&")'%'%)&%($)+'+'%&%'!""!%!%!)%)*#$*!'!"&$**&%"(%*+!%'!)(&("$)"'"#+!!%"&!!*%'*'%('$"'&+)*""%()#*'
@r5671
CANACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACG
+
?C3E5.:A2@/G&G&6E*)E#G/EGD,+;:&67F-+$B0';
@r5672
CTGCTGCTTNATAAATTTTCAGATATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGG
+
><&6%G)7+89(;H-EC,!:>7F:26E";<-92'&8%>&%H<"7)1G@<!''+G(>%7E7+.&0#A83B7(.FD-'+(('B4*0B!!?C
@r5673
NTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATT
+
#74G8:D+'(.8&$@?'9/&472)=3H9A=F&%"A>:+,-AG4=3#F688;;D6
@r5674
NGTCTGTTGAGCTCATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTNATGGTGTTATTCCCGATGCTTTTNGAAGTTCGCAGAATCGTATGTGTAGTAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTAT
+
#7-3</A<.?F31#A;7H)C+7.:3%"7=G&@:)&3-B)D9'"557*<1?<4(H/';E3>F",.(0#FC;3"617$GH5-'<*7F)"0//1(03.)*1:-H&+.&4)C5))3"@0H=8,2G&"=AA='#99?,!.BF.24'%C$@?47,0#B?2+3;::#C9,BG>-@-=G8GF,'G6E#*';37768<1%8D-.&7G:
@r5675
CTATGCGCCGACCAGAACANCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACA
+
F.)*/<A1E(0409,1&/AB<:2>#H.#DE&GA)@>#01H<!&6/AE?AE-0#CH$1D)1@!,-D7EGB1"!4E(/D6**@01)9
@r5676
TCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCA
+
71778:7-+;5-0-77=$G1D:*977@@%:+7431.9=::/*>-57#=-731B
@r5677
CNAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGCTCGGGGATTCAGTAACANTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTC
+
&$&$%%+(!"('"%(%($+$'%)!&!$)"!&+'#'(&')$""*$+!"!)'&+!$"#'*%(!)&$+$)!$!"#++'))'&)*"&())##((%#%*'*%%"+$)))"*)+!!#'$%")('""%%%##)!*'+(!!#&++%$#(#'*
@r5678
GTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACA
+
<)%)(:D3ECB+;E&;+*EF8175)*9@)#18>B'512?$C0GGF
@r5679
AGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATT
+
4G3F,35!?/2%$,,9<#CE(%@838?-8"/<;(66:@?A6.
@r5680
GCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCG
+
C>%/84F>*.4F"1-77A./E&2">G"/9'/.<#>F=?"8D!?80@,E;3(#D0G3#,-+","D>6/=21)A/=@BC+<$*@!GD9GB='?<*D3#H!4$$B7=&>*E!">:3$8>%/5#!5-'$3A?
@r5681
CATNCCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCNGGCGTGTCCATATCGNGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTNGCAGACGGGCNA
+
$*'&+'(!*#'#!+(!&**)*"$%*$&$"!++&(!++%#(%("!!"$$"*"$'"$%$&"(&%#(!)&%%&"!%*("()*"')(&)"#!##*(+*$"!'!!%*$&"*!%**"('!*$*%!&)#)!#$"""+(#&#$#*($
@r5682
GTNCTNAGCNNGATGACANAGNTTANCGACGCGTCACCTGATGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGNTTTTGCTACCACCATGACTAA
+
&&$(&"!$*!"$%($""$!'!)&$'!+*(&')!(+)!'"(*&#*$#&''(&+$$)++)&%$)$&#(+#&!*(#')#&'(+)%%(#("#(#(!''(*$)#*$**'"+*"&'''$
@r5683
GNNCTNGTNGANAAANCCCCGCAANNGNCNCNCNNNCGANGAAGCTNNNNNTNTANNNNNNNNGNACNCTNGNTNTCGNNTCNNNNANCCNNAGNCCNNNNNCTGNNTNTGCCGCNCNNNNTCCGGGNTNAANTTNTANNN
+
#"!$!"$$!!#"#$!""#$$$#""!!#!"!$$"#!"#!!!!##$"!"$!$!""!$!!!##$#"$$$$#$$!!!!!""#$"$#!$"#$!"$#!"!"#!#!!!###"!!$!$"##$#!$$$!!#$!"$$$$!$$!$$!##"#$
@r5684
NGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGC
+
*/?6)>A7;F='HA?/<D0+B:,53,9H7-=)(D1.;,)7:'+,*40D66;C.*;62<!:"G8
@r5685
TGGAGACAGNGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGNCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAAC
+
)>?7A>"$-2;4.8#)GH5H/F@!G:%G9%0"!>:'*DD1)F29+;#3A./=(,):-1A!6+#*D2CF4>B40BG>")HH6#C<4:>D*,.B(@/*:8#?6G?.7#?B23EB8
@r5686
AATGTCCGGTGTCATGCTGCCACCTTCNGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATNTCTNGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCG
+
@CE,*?:'#%#E:)+&.'6.C57/2#;(%(8@H?6*%?BC&"!.')87G)E%4C?@<C2=G"-/969-*<3.A@>#A,-G8@*'.,=!/&C2D+2G$68AA?.0F)=#G,"E;9C,0*(9;5'*E%5+0A--68&D2?6)8.H'4B*6&!H#.6#4(%3%:5%'?EA(
@r5687
NCTCANTGNGCGCGGTGAGTGCCTCCTTTGTACTGTCCACG
+
"$!&"$$)$%+'###&%#**!%%(!%!+*%##++*%$#*#"
@r5688
ATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACNGCAGTTCCG
+
A*2E64#G4)#-=G/0=:&53G/.=03*@&2>#!$-?A/E0467HA1D1/DF*%
@r5689
CAANTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCG
+
)&$!*'+$$'+%&('$$#$)&')$*"&)#")"$()(**%')%%+#%$*%
@r5690
TTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAAT
+
84*@4/=$!C+$CF5?2%'B@E8-B&.6D%/$#(8#*A<B3EA;3(F>(-(1(*(*@9B.1,)A.03@-)E=.$'+C%(!:2!237G,,+.G930
@r5691
CGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATNTATCACCCCAGATGG
+
83(7DDC9:!8;@42;C,BFH8<3'H<=>)%=$&;+ED26/#*?H%"6D8"(<<"CD%F02!@3E=90$&42/8@:=1:H:%D8"D76;+F;8D#$&81<"?FD)"F$>(<:9?1'@.G%G0=.*G5?>.2G<=(+-,=9%F#6"?:!/"5&E+%#.069-4%4)D#H0-@7G
@r5692
NTNACNCATCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTAT
+
*$(%*&*#+)*"*'%"%$)!"*&)*$)&*)+&%%("#%*"&***$&#)#(*""+#"!'%+"$$
@r5693
CATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGT
+
"C+*C)E:3,?FA,6<)6&3,@.$1H6D(H>7%)47&1(0F:G>2G=H#C=G+690+%*"'%72)6!:7751",,,G$@0?
@r5694
GNCNGACTAAATAGTAATGAATTAACAAAGNTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTCCTTTAGCAAGATTTTCC
+
!!()!"!+))'%'!#)")"$("()'!'#$+!%()#))!'$$+*$&("*+''"")"()()#*##(!'""%*'&(()+"+'())'%'$+***#(!)*'(#&#%&
@r5695
NTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGNTCATGGATATTTGNAACCCATCGGAAAN
+
"+9C#@)36)G+/0#0#&$7$.&6AF+>,*+2&!1-2*$1-?$?H?!>(-$?@3(=/&72-'5<(9G&(/;G1>1D@73
@r5696
NGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCC
+
"C$&9*3/BD0,5'120C!99!&<0#4!$4:,/-A4$%D*
@r5697
NGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGGATGATGTGCTCCTTATTTATACATAANGANAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTANAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAA
+
'+'%!*(*%)++""#&$+&!'&('(&#*(*)%$"("%*"$'%%&())+'#!"&*!($%(&+&$+$"#(+)!*'++"%+'$"&&"!!''"#('&*$"!(&"*($#!!&%&"%+%$#)&(%()%'!"(&$''&#$!(#(*%##)#('(!*!"!%*)"
@r5698
TTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTNTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTNATGACGANGAAGAACGGAANCGCCNTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCC
+
G/-7/20-0GD4764%D)A/?A1"%5.1@*,9E(82:B,D!,%;.#!0.51B9C/BHE+A,1F%8D9182=>5-!F6<&5,$105#&.%.('D*%5'0,7*;;<:17+'A/#@586HC<5G)/(3*5F&F/+75@?'(54364/<8?C,$?@4!(1H,74#4(8/C9/GG&;>1>5;8A'<%4<B'22/8:7H$:/(85)=
@r5699
TTTAANGTGATATATGGAAGAAGAATTTGAATCNAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACT
+
,)>+D8..,F4+6,3)91'*85>C>@"<=<D+5>>6@7$31?@8+HD$(A!F!H"73;=7A%:0>!3&1&B9F.F9)%C$.'52'
@r5700
NGACCACCGACTGTGAGCCACTTCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGNCCGGCAATCACGCTCACATAACGTCCGCGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGNGGCGAACTCCAGGGAAGCCATCA
+
'%<=3H&31H#D*!'/9#B"H3C>)E@B8*@C!%D?7!C(,9*?4G,8)5-FABC2!*:0H5-A$87'2?9/"3%/364;08?F"">E?H29%!&5'6$176?3%%6@&'1/*HF"#3*+D'$&(05G8),;+@/>)?DH39D*<>?DGF'-83$,HC&.*40=,.&%D<%?A74%9H$!-&
@r5701
NCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGG
+
$(#<24H--)/0="";3%;B@%0=;875:%D5<<"0D78@7%,$H&3)-HE:6>D/2!-=B=57%6$@:$F2!0B.#
@r5702
AGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGNTATCACCAACCCAGAAAACAATGTATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAATAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGAT
+
6):2C@/'*8#@&767>,EH8D@<5.""/58EGCG7>9H$*./(EBC@=+*@!5-7(G=08#:$?-)C0D<F@?'4;BE&:#3">3C"0H$B=A$66F:-=!:42',%6&BH8>9;::$&*764$D;A6-CH>'+-ED"38>$#80809D36E4;(A+7A6-6343&EG6.(BFA;B<9C0&;D3-07/"<<D3%2.%7G?7?-)*H-HHA,!H.H6*')0-!$>7(B&57G6.32A$1E.'B=.&G-/D:"-$G6=G<#=(G)>:G7,(%-'=5:G,..B5!?!?6+=ED4$@1+1!!':.F3D&809$+.C1%;,;DB!6,1,";5,&,AE=5D8&7F<+>B9;*)6%+3:#$';2G0B##&1F%B(*-%($/=)D./">9)%/?3=%
@r5703
ATCNTCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTANNCAG
+
H>5G%38@><967%6F940"/C<$-)*+A33"%D"D7@/-54+H#!,-(2%:F7/&BH4E#%"(#/2AF$>A1.3@?*4<&-E=H@=95C6E9>AFAFE8<:$+4);#E2&.&4#E.<
@r5704
GANATGTGGTCAGNGATTTCTGCTCGGCGATGCGCTGTAT
+
%#)'(*&&)#()*%+#&$&("#+"!+)'')*+&))"#"!'
@r5705
TGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGT
+
*+$#!)&%)(#!%!%)'"++("+&(&'!'+")(*$%$%%&%%!'
@r5706
CGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGC
+
B+'3?0-/,7B91%A2"#<$=5!"F:5%*#*E@DBC@8H.&)416?-5A/&-?9A+(?>#
@r5707
AGGANGCGCCCTCCGGCNCAGAAGCGGCATCAGCAAAGGCT
+
(##$""&'!''+%)#%+)$$#$+"%)!'!++(*'**)"")*
@r5708
CAGCGGCAGTCGTTGAACAGTCGCTGAGNCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTNTGCTGCCTGCACAGTTCACCGACGTNGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGG
+
$++()$$$%"+$"($#&*#+)#&'"&+*%$)*)"+%'%+"*%)$$)*&(&!*)!(#++*+&(%#)++"""(%)+)($)$(!!)*"$$*+&!&!#)%#**$)*+&"&")%'+$!"'$+""!%)*'!$+$&)&&$*$'*()(&!!+&"&)$!$("&'&))&))*+&&$+!'+%(&%#!&*(!%#*&&(
@r5709
ACGNCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGANCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCCGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGAC
+
7,AF)CAD7F%%D;#1/F>H''-<%H+H1AC%;6F+>$"495+06H,.?/&&8792%+0GEC5D?'D9).++5(,,>'#=F>A*+:AHE705;6DB-*0E1,6=07:E*9'"$,H%A"/FG95@7&7-%<-49.#(/$7'0@57E"+&"%"%.H0$=!.F+&$B+%"H491@>E>F+>EGHAA/?>=64$;-1-8D#+42'5).9B9F*/'6$!6(.%BA,3)8H/-;@%&=)D!3('!%0G?1#!0=44.<9B.94>+5;6)7B5C#8.:07$!275&16-"8>!.@A#*$4:9A$@*#6/.6<<82%9!-:(
@r5710
GCTTCAGTGATTGCGATTCGCCTGTCNCTGCCTAANNCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGC
+
@+4%A(D>G=.3%(D@$E$#E9*E"@F'3&9$,>!7<;'B-G7)F39*50+G):91CD+6$*$?+))$C*1H:+B1$=:/;4(>.4/>-*($7+3*%/.)13!?9:@@;;$488F%D>
@r5711
TCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAA
+
CABF-7EH--D3/B&%&!H-,6>.66C(%2A#2CFB*/;A:(+C&6845*
@r5712
ATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACNTATTTAACCTAAATTAAAAGATTACTCCATAAGCA
+
<5"7;#ACE)9@=&<)6C/0'3-*=3%G:8F(03:@!,53#-#5'3B$"DA&4D1*;=A5G2GE*>60"&&7%<#)>6E.#+=+6&%H'',-1/.5(&1+#=8DG!H"95%D5$("043,(3B@@9'61:2D):?E&8>=.B>B<%24#"8E-%4(8H
@r5713
TTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCANAGGAGATATGGTAGAGCCGCAGGCACGTCGTATGCAGGA
+
,&4&"!&H4EC"@0&=B,E*2=<(,#C#(?08*#9,%(C+>1=?A08&<9-3$2!0%G"B/0'CE98"2-0.&=<#E>75-+1&:+,A:#=(H*=(HG>!G.F?;?4F0<1C%!36"H@#C2>0,?9
@r5714
TCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGA
+
;B8#;H=H=@##>>08@+EC+;03('+*-.52G;G9D4D%/0;@94C-:D5&FHHGC(':8).=%,:E"F=92-++2#&!'*G8-?C9G%"@/:D;:=<'?0:G7=8/,0*E21&FD5;-4H!(D198"")9360DB<4B4.@4==+%49#,>
@r5715
AGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGNTCTTCCTGACGGGCGGTATATTTCTCCANCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTNGTCCTGTTGANTCTGCTGCTCAGCCTTCTTTAGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAANGCGCCCGCGCTTCATCGTTAACNAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCATATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTAACAGGACGACCAATATCCAGCA
+
:A((-6*B'3E=C*GC/7)DH=)+9&-4?>CF4*@:<1H='%2!<@.*2=*)1"A'*<:51A%<1'.,3<'&=C8-G>4D.A4"H0EA9G)=84#8:%#(E0FD>F-5";*!%9B..9!>8/CB;(,H0(=:=?/DA-(6#&9,G<!E06).GA>#%A0;"B*1,=+5)5E&H)H"#3H9B)8"0@,#8"B#AE(*0EH'602CE*(3+*.)A8,$A5A372/G.G!>G.*E/929$B;*B(E5)5'560@+:;0>B#*6)62-9,36DHD#G4018D-8G6%<73GH(/==(.=)H-04>48D8/.'38(3>-CFHAG=67+7.*"BB=88E5*GB&C4-#/2@/"-8B8";$A:7.$B1?0<'051?4HFHF$+7,?/+A
@r5716
CGCCCGGCTGTGCCNCTGACAACGGCACCTGATACAGCCCCGTC
+
&@<%G7>!!+.DH(E&AC12HG7.&2&8F#,+(-8+<?#06/10
@r5717
AACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTNCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTT
+
0>#)A;BH:/8">4F?8H=AA83B(D+A04/01DD:"@:-.840H)$"0)#27>37EE'C28'.@:E4B!>?"!;4'#+"E4:C%#)2,G6,/G58H@$&==-7F)/HC<&'E$+0HG)*73#$)H%C3,"5CH/+;2.?
@r5718
CCGCAGCGTTCACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACC
+
16D$(=!*'78GF;6768$BB?)"/E2A->@+FD**34&84>=2@$$-%B53G-@F2G2%*+D0&!868%B11;
@r5719
AACGGCAATCTGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACNGGATTTTTTTATGT
+
*')+'#&&&$$&('#"))(+$)*&(*!$"("$!""*%%%*&#*)*!&))*%*&)+%"#*(&$)##*)")!!*')(")#!*(
@r5720
NTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTAC
+
!C$H&8E.02<F@7!1=)418;5=$':$!F..3<"6=E.?B:
@r5721
NNANCNGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTNCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTT
+
&!%#*"!(+'!"'!*")&)$'+&+%"&+"$%&#('*(&!!&))$+#&!#*)"*#$'%*)*"#''**%'+&*(#"(&#()&*"%"!!*!'#$!+##%+$+)*%#%
@r5722
ACGCTGATGGCGGCGGCGAAAANGGATTATGAAGCGACGCTGAA
+
:,6(G060"*1B'#:$@'8+>EC//8B;2G?$?4B-)G(%6;!-
@r5723
CGGTTTGGAGGANTTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGA
+
F<H%&+C+$4AG?/4+('(B?B0@'(24*=:?F2')-H<>HG(B6%&8-;G;6--#-7B>)G42.#!(19),
@r5724
TACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAA
+
(5#5%?6(%()"AF-8G3#11G0!:-996B-H3'EF03H"<")B=;!&&%7G**E!3>0.)&/%1E@
@r5725
GTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGANGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCC
+
52;,,,,+(4&"'5:;=)FA1E5;5G*,("DE/C>B<':1-:.*',#G8-::8=56E(?<2H6#5(3"A:,7=)7)F#AA>3G%@!6G8,<!$":!2A099+H%"<&-?+A3%"%/$8C;62<3<;+E&FD,5#;##%B!:'/E)4DB"C>:),%?4!-(5D/*$$7+>>
@r5726
GTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGNAATGGATCCACTCGTTATTCNCGGACGAGTGTTCAGTAA
+
+:*+(44*H@4!/6'A7>9B$9C&E?H1/)+))1/5+(!=:.91E:00158'1F,AD>+%3G)76(-/#?CG4$.=42<A96*-5@%H)!)#)(H3$5%B;?*<&$")AH*
@r5727
TGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTT
+
6D#61,$'?8'&0%,/3;*323F,6EH92=9$;80F@@".
@r5728
CNATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTNTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATNACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCNTGTTCAGA
+
%"5#BH(7"+H534C5B9)A&BH1GHEC-A>A77,29#H4/@8@E(1'@E)202<&$B3(C8$96=D$$=2F+G(AE=E?E-&+>CH8&B$$979-&2$461HC23,%!=%7&9*6&)@"116.58D-9D@C3E0;DCC%#7DDC0$<C?<$1>?#!@05F#5#5'F20+?*6-A+E&*D9@*.+:.*:7-F+=/)@@=A)"5:<1%(=7<2AD-6C<BF*76*G'D42D4:3!-0>=%))@)9B-
@r5729
GAGTTGCCCATCGATANGGGCAACTCTNTCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGAAGGCTGCATTATCCAN
+
D846?:A>%.B.6"%/$;..3+?"$%$H/GFF5BE;2")-15$7%"8)%DG="93-((+(1C/E8<24$.!*C'<00FE6,?8'D6.*/3;,'*:@@":#.G//+&!;GA0DD+6&B>:@1(6&*?.96*>3#<D?'7"C#/22B,%G?(+/)"109
@r5730
TTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATATGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTC
+
3E:2G5,*D%""7&;H=81">C>':B?)HG%01!/5G'')8&+C!G"B$!>->&03!>C98>'!$?2*0C'<+#-$&!93:<?+3,:%$3)8H?"/3@!.5>;+CB0/<88$/4"4632+AF#7>#;*56EF1F@H,G.05-!)9'77/221:BEAE*)7GD<?*>#)*D/2:5A3*A8'.0,:)*F5H=4+4C=/
@r5731
NATTGATGTGGTGAAAATCCCGATGGCGGTGCCGNTGACCACGGCGTTTAAACAAAATATNGAGCGGATACGG
+
%,<#7&,17H&E5=4<(D4.&38,6%78<?H('5B2-8!C1;3@8;,!F42>=C551HD=6$?,4DG#!$4"/
@r5732
NTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATNCCAATAACGCTTCACTCGAGGCGTTTTTNGTGATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCCCTTCCC
+
&3);E-A7@0,3G8,"14%20E@8D?$C?"'@='=79;03)2>99-F)EFD;>4*5E3'8E"/2(?6:GG;>8D22%,6<CF-GG066$.')"9;?243B>E+8F&51;%<!EBG484A!E/8@;-<D=8267>4H)H/C=8D.#%46=,-/$,)0C=/H>CA-0=<#(>0B)DD9,1>3EF;042-<6HC?44&D7=/1
@r5733
TTNCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACNGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTC
+
(#(++**!$"%)#%'$"(#*)'%*"&%+#%!')#'"+()')*'!*&%%)"$&**)'%%)'*"")!!**'#!#'!+#)*$$&!"&)#%$!#'+!#$"'(+%)!&)**('"&$&%$#))+*!""))'&%)$$))&**!"*$!"#%%%&#$(!"$#$$(&'++$"%+("&+!)')++""))!%$#($
@r5734
CCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTA
+
1D*>@>).H>E(B%0?"H521?-?03F/5*#%()*F0.?04:,?-'-HC,??-:C9
@r5735
CAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCA
+
=AB=+B-:#6.$D7249HG$D".*.;;)@6)=@<?H7048,BC$/!H8'>
@r5736
NATGGTCGCCCNGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAG
+
7<%)1'/H.G=$5"*'%>DE76!3<A'$'7.G'569.2.-:-G+H"/#@@?H"--+D59H.<.#-F8#!C#@(#=E=:>G543?9C,5337F$'8H:@31@@E')#3E8;+?4..;;!5H030+
@r5737
GGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTNGNGGTGGACAAG
+
FC#G(ACB2,)EB'&97#+"H&C/E9HF1;**H<H/)$-DE&5C'84C:=G3:C<+&!DA@-+B"0/(8)$).!/
@r5738
TCAAACGGTGCAATGAAGCCAAGTTAGNACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAAC
+
?'+-F46+B.7.4HA!G.2/6.217;&9?%$!B)4G?6#8*-001:>(!6#F%B<H@3!BD?%-DFC3H'"/"%5,*CBAD%#>>'*F;D6>*3&1,>(4-3$(,86D6HD2F
@r5739
GCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCANAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCAACGTTCATTCATATATGC
+
<.<H8A8!&8G.G$#6"//$A605EH276:,!%.+AC(4110%E266(-E%*6=&*(=8E("%"2/!/F3?",(/,A4?&D(E('5AGB.-=H+09E1=$8C
@r5740
AAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCNATCCAGTGCAAAGCTTT
+
<8-AC:5)&6D)(E48F>)8G".)E/E&4<=@&)"7HFFD?.?&,HA35D9?6E
@r5741
NCGCCCNACGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAANACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGNGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTNATTTACAGCGGCAGCCATANGGT
+
"'%&((++)'!!%"(#(+$%#(!+'&&)(&+%)"!&&!"))!#*&)+"$"*+&""$*)+)+(%"+%*#!$&("+%+'$#*#"+&&&+'(!'#)!&!"")'#!%$#(+*%'*!&&'+!!'#$%#"'+*)$)%!%*#&**((&&!&"*+)#+$&%(!&"+$())&**'&%*)&%&!%++%'%#()&!$&+*%'&(!&'("%')&("(('(#"%++*%!))&"*+!%&+#")%#'$*"$+!&"(**"'(*#"'*#)%#'+($+$*'
@r5742
AACGCCGTTCACGGTGATGGTCATACGACTGACCGACACGGTGGCTTTTGT
+
3@97D>!C>,7=>4+D8.7E(8()@6;G5"F?$+&&7*52E+:AF*GABC%
@r5743
TCAGGAAAGGCGTAAATTTCTTTCGTCNACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACNGCGCAT
+
(79G$703G9B+*(HG!CG@$CF"::!%G5EBEAB!&A=75.$01-6*.7GC,E4FB!@?#112B91/')>F1!D"D!3<6<
@r5744
GGCAATNTTCTGCCTGTTCTGTACGGNGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTNGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCG
+
;0H=%E9)<A3&-.-G2$:&2%>B:2E68)G4"AD@A'08)">07B9D(73,8F'5B=A2&#5-,13>C/:A+H1-#!0H-<5?7'($=.?"D@<84$?"5H6(!A/28.G$8&?<@%B85-=&%8*?9(@!@A2'EG2>9E4D=G-!!!(
@r5745
GCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCANGGATATTTGTAACCCATCGGNA
+
1GA19%HE1;(D59?HC6FF?5H<4C!&G93H3-+61952:'*#&HE77F6C!>#2:65/'"B5@0D)A-=65E&:'.
@r5746
NACCNGNGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGA
+
"%#&!%*+)&%"(&$#"+#("!"+(&#**+%'$##&)("%'&*+&(#))$
@r5747
GTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACNCTTCATGGTGAGCGTGTT
+
A.E3('4+%"+-=C;A45B=581#-6-@?G0H'"/H%%-A.?E'#$49!+50B.*H9""4G.+0*6$D0?)1
@r5748
AGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATG
+
F0:305H$9/%)'8033<$,%$3D2*-*;<FE;2*;(A,(/-77G#;H9?*=7H$<6);)6/AE-/"88'!#$;>:;G;4E$9&1(5#B,6;G3'D18H(2;26&H3;/G>>,CCE!"*%8DHA4C6/1C>B/%3%
@r5749
TTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCAT
+
H5F9@26/0#5#$35%23"+<2+$#H:B49<:40?8>!F$1#6-??<032!
@r5750
GTCAGGTGCGATGAATCGTCATTGTATTCCCCGATTAACTATGTCCAGAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTNGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGAC
+
/$:?%F>CA*B".4'.$>%.%?#&18,%59+#$6C04<$+CF::1(:;.?38'(0&D3'H4*$?1)G288A66)53%C>#+>F!H*3+D(<A;-8&15H"B1?&D%4,1%C++FA4'2-!C&1*)+'DGCG;0+F$BC595;:4//4@H2@$,9#"
@r5751
CGGAGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGANTCAAATGCTGCAGCCGCCCAGGCGGGAGGTTTAAGACCNGCTGCACGGCGCTCCANCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGNCACCGCGTTTTGCACACTCTTTCTCGTAGGTANTTAGTCCGGCTTNTATCAGCATCACCGCTTCCAGAACTTCTTTNAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCT
+
$"('+((($$#'#!!+(+"!%('"$"*!)')%'*!!*%&%!((%!!#%!%!)%*'%"&)(**$*'&"!#*'($!!()''+*'##!*%!"$%'"(**#"+!')+!"'+(*$'$')*!+&'%**)+*&&)")+)&&#"*!+'&+%+%+'"#+"*))"+)')(#+(*))&!()*()("+"*%$(($'&&(($+()&*!"*%!%)(+'!!&#$#$&'+!%#"+'$&+$!#!+)&(+$)!$#)'*$&$+()"%'%')"%*)&"(+*!#+'"%&"'&")+'$'#&")'!*)%%&+')"$'"(*)+#$%()*#$%($#)!"($%)##+$*'#"%(+!)%&$(%%+($$(&#+*#"'!*+)('#+'%+
@r5752
GAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATA
+
'17@,'2"E2B$1%%='->/+2+:6<H"A43-H(+3@'%297+<"H@:CB/"1&+A92#",FE.
@r5753
ANACGNAANTCATNGTTNNNNNCNAANGCNCCNTCTNNGTNCNTCCNTNGCNNAATGATCANTNN
+
$$$$#!"!#"###"$#""""#$$"""""#!!#"#$$"""######$""!"!$!"$#$$!##$$"!
@r5754
CGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTNCGTCAGGCATGTTCTGCATGATGATGCGACGGCGGCGNTNAGCCGGGTCCGCCAGATTCNGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGC
+
5#<!>)36=<GG:&<0/>51E!;<E/<..33*C<7-";5679-B;9G.9D)?5,<AB;<=>::@EF<'@G$)91=5&<7=(2*$&3$"+!/93,E>&?<$3)5!(;?50B3&#A;7H!*&D?;2*>+HD#!%:03C$+'-=57!@!
@r5755
CAANTNNAANTNANNANATTTGGCNATANNATGCNTACNGCNCAGNCTNGNTNANNNNNNTGNTNGNNTNCGANNANGCCANNNNGNACTNGTNNGTNCGGTNCTGNNTCCNGNAATNTCTNTANNNNNNNGNCCGNNCANNGGCNTNCCNNNNCNNNANTCACNNTNCNTNGNGCTCNNNAANNNNANGNNNTNANNNNNGGNNCANNNANAACANANNANCGNACCGTTNNGCANNGTGNTNNTTATAGTNACGCTCNGTANNGNNANGNAAACTCNCANANCTNTATNCNCNCCACTNTTGGACNNNCAGATGTTANNTTGNTTNGNCTANNTNNNCTNANTNGCNNATANGNGNTTCNNCTNNNCCCCTNCNTANNGTNNNNAGNGGTTTANNNCAACNNTGGNNCTNNNNTGGGNNGNNTAANTANCCNCGNCGNGCNTAGNGNCCGNGTNAGAGNANTNATAATNNNTNNANGNNTNTANGCANATACNANNTNNNNTCNTCNTCTAAACNNGTAT
+
##!!$!"!"###"!$#$###$###!$!#$"###""#$#!"$#"$#"$$!##$$#"#"!!#$!"$!"!!!$"""#"$#""#####!#""!"$###$#$##!$$!"##!!"$##$"$!$#!""#"$$#""#"#!"!####"##!"$"!#"!$""$"$##$!"$!!#!!!$$#$"$!"###"#$$"!$!$#"$$"!$#$""#!#!"!!##"!""$#!#!$#!$""!"""###$$!####!!$$#$""$#$!$#$#!$""$!$$$$"!!$"!"$"#$"#!"##$$###$"""###$!!"!###""""$$$#"""$$!#!$"$"#!"!#!""!$$$"""""$!!$#"$$$!$!$#""$$"$!$""#"!"$$$"$#!#!!$###"$""#!"!""!##!#"#""$$"!""!"$!#!$#!!$#$""$#!"#!#"$$"$!##!#!"""$"#!!#$"!""!$!$"#!$"$"##"#$"$#$""!!#!"#$!##"##!!#$##$#"$"###!$$""#""""$!#"$!""#"#$#
@r5756
CGCACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCATACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTG
+
(#7C(G!.FG4+4(H';7&A5%9='F)8:C5F>7'H$0#$%-*G7-#3HG<H+!1#15H(?@$5F@D)B@'H=06E,G1A=/3(E3&D&4$F&#%H@B!/3!7.601G&0+$H*3<*F#H*%!#-/@4<D)H3(5%&@??8#37%H%>H$&@11GDD6H!#8+#=G8)A$-H-;9495B-EC25C+"(C.FF.;/4<52$"A+-=%;<-?*9GGBG>B4C/>*+!B<0"AH*"G--DD(<63E$4<9+FC46'7),($/+(@+$#C*4F5*>"9H"4G33C3C7@?39""<C<@)8;2EFC*75#+'<CG=H0;1"1EGH;>%@)F:26>"%<"=4/$3B>>6FA1&
@r5757
TTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCANCGGTGCAGCACCTGACCGCAG
+
)*,3">!;G)179>7D*#B4>62H35F'AD>'/#+FE2<;=1G9,@4E>;*7@G&;.#-7=%++40'
@r5758
TGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTC
+
4FC+!/+3A@0*(2D80>,9?/&-.B!:'-*FBG#&G2+&
@r5759
CCAGATTATGTCGGTGATACTTCGTCGCNGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTT
+
!>"6DGA20C@/90,'17F8FF='?<GC*5H,>.E*&!5E&'2@8;)1)89C?/<"8.>A!86!"/3(#A"F,!2G5<)G'F:#
@r5760
NNNNNCAGAAACAGGCGCTGGGCATCAGCGTGGTCTNAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACAATG
+
)!"!%!)$*+!*%$#*'((&#%++&##++$%"#%)*(("*'%#(")"*()*)(&(%'+$%"$#%#()#*&+)))%+'+"*+*%%(*"+*%&"(%('&%&)')
@r5761
TGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACT
+
?:59%8?38!;1,F=%(%.H-08%!*B":&4$)1F0#*#D.1-$G2!8H.G#A!'F6@>
@r5762
TGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGNG
+
785,(F8!H+'!?9>AEB@9H*#=+*--F-:1A.>",<.<%:E
@r5763
GTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCA
+
D83<25F&+EFC-2(!/1'4<+>+2?#/#F82"*#)?21=#>+;:C&$2-2E5??A
@r5764
CCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCT
+
;BB%G:E<*-0D)!D&;&E(7+!>+(6H1<F/8=#@"C9$.)F5E!2%4-3
@r5765
GCGGTGCGTTTACNAAAACAGTAATCGACGCAACGATNTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCG
+
,.;-,>GC5;'?,A;-7.0'*@&(?&".-39FE%23A(.,,6/!C/2"'?E9=F@4*1&8/><>'**<#D@=6C&40:99'8H!
@r5766
CATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATG
+
6@*DB+;<:A393.!%E*(:8?0=/%%F53C@G97,A2'8@@
@r5767
GACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACNAAACATAGCAATTCAGATCTC
+
9<0=D"A1CF)18:F-<7&E1/<&H5&G,$(CB:A.G&+7(;>B#<"G1C#?B3HF67-B%'H%35E$(7)(C$9;63452785*11;*?+8AF*2:C*;CH/C4E)=93&FH$'&@@/6!;;1,,@G8'*+-.
@r5768
GGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGNTTCTGCCGACGNGCTACGCGCATTCCTGTGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCG
+
)%+*!'***%&#*%+%&#&')##'"&(''#*$+$+!#!)!('%(+%)#)&*$"$&#$!$$+&#$(%&'$*'"!''#&%'))&*$'$%&)$$&"*&"'#&%'&)&&''!)($%(&((('+#"*+#%'$)&
@r5769
CGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATT
+
G4EB;($!$AF9#H0D/)915++B;D@:H$+CD#D.>!E<7-->F/>@G#%>/H@B.=.!+>'/C7#80CAC;6C?F//A,'B'"%:5A")D7A1,%<.-3(?;4*C74FE>/
@r5770
AGGATATTGCNCTANCAGTAGGGAAACTGCGTGTNGAGCTTGCAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGNGTA
+
0$$A%@!11.8E!.H23.:3E@<.4?6+FA;'@0.:EB#FEACB*H(/F53AFB$!D'D=))8+&5EG84.B.D/-=G=2!'"2&04.(-E#-G,B5<2B$)#-#H.!>&:B'9
@r5771
NATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATAGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAA
+
"2>%$4/+'#DG9*,@%53(5C$&.70EE.@A(5'>+6<4.!D!1FH6@-HG%4HHF4<-(>?!%*<:F>C9.25E+C,!(9AEB!>A/</E92@,$%A&7D:=3#&)(,E@+H5A1G0?#2&H6(>;+C<0;FGH4;EBF>4$"5#E/.8(<-"<&G3,02:*A;CC>1<*1HG/F:H%7H$43$&0+2'8/D2G-&5,=5B$BAC0
@r5772
CTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATC
+
,75">"&.6$E>-=5E80-(?"=8%3/59*!"4G)AC*%@>>;*<H$;FA3&/'(1403/0/
@r5773
TTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCAT
+
&')))+%('#$)!+%&#%#$($$#'+)+%&!&%+#+"%&")$(*)#""&&&+'
@r5774
CGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATGCGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTNTGTACTCCAGCGTCTCAT
+
0:"+1=G4'C/FC03)*<(E@=2.?==)"C&'>::2"314H?<(($%.9&C>4B#*$+9,)9$-B0:"C/!0+3D@5'/2!0>50@012'%-:GE,?!H!"*F"%$C5B9+3
@r5775
ACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGAT
+
5*GE1A;#'CF:2E-0'B0:',$E$9+&/6?F@8&"E-$4
@r5776
CGGNCATGANGGTGATCGCATCGGTNCNGTTAACAAGTTCATCAGCCAGTCCGGCATNAATGGCCTCCTGACCGCTGTAC
+
'%#&%&')+'!$&+%*)&!$&$)*('('%"'&)%()$'&%$+)!)#(%#+&'('$$&#)!*&*$#"$$)''#$#"(%!(*
@r5777
CGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGT
+
;;(6D.;+"F-:AHBA0B?+,&&CE$7#".:)&&*F#<6)*C7'>"*GH*/=8E$;+<;%-FF+H'2,060(18,
@r5778
TATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGG
+
H'/7,&1*'3%3;9)?2(&"?%*A:53H?.)GB&E1/#;>-H0;C?;-''*,;E)79.F/;,A'6H%H""H*,?-*B@(;*<."CE2H3'!(9H-&=;
@r5779
CCAAAANTACTGGTNNNACNCGGNNGNGNAATNANGGTNNGCCNNTNNNCTTTNNGNNTNNNGNTCCNTTCACTNNNTNANGGTTAANGTNNNGTNTNGNANGNTNNTTNAAANCNN
+
"""!!#"$$$##!$$!$$##"#$!#$!$!#!#!$#""!##"$"!!$"!#"$$!!!!#"!!$#"#$"$"$$$$$!!!"#!#!"!##!#"""#$!"#"!"$#"!#$!"#"!$"#$!!#"
@r5780
NTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGAC
+
&>8$#-@<51,/CD19GHB@1E4$+B6*G:43&#$,51F@A5<E+=$(HG(;#5;*"741BA%(>B;/?
@r5781
GCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAANGATTAG
+
="0G%?"5'#.:F>(04'#(H&.#7)@&?8*F,-137#;3>.-'.'D=3<:C<D!?B9,(<88"F4-79/BC1DF0='5<H'=."BF>3%B)=(6.1.0>#E?,3/A3'!D-=D<53">?';>?@H-,=;A$G30
@r5782
AAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCAT
+
D(F=.#>GC)$D+/C,1-/5B870@<+-*43$+?8<)0(A
@r5783
ATACCCCGTGAGTTACCCGGCGNGCGCGCCTCGTTCATTCACGTTTTTGAACC
+
-$4-39/6D9F<!CFF#H!"&"4B3'&@-60344B<$08:%D#C8;'24!F)"
@r5784
TTTCATTACTCACTTCCCCCCTTTTTTGCAGANAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTCAGCCTACAACCTTAGTAGNTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATG
+
@'3=7#'&.D45473/$),2%$%%#!)E&+#0B.03!75"*?@,")''G:F:5CGC+1BD*4%39!8")?E#4A,<65,6!'.H$;A02<EFE5#D:G;+@6)@G":D'/G,4C#%D@4463.=#5G1;B5;##B/D>$4A+:.;E+'.;@77&23,;
@r5785
AGNATGGNCNCCANNGGAATGTANCGAATGNNTATTAATNGCCGNTATNGATACAGCAGGAATATTTGATTCAGATGATATTACTATCAAGGCCGCCTGAGTGCNGTTTTACCGTATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCAT
+
*'$*)(&!*!)(*"&)(%!$))*&$)'($(##**"!$*#&"('&$((%+!#%$%"'&%&*$&''*$%!%')*"##&"#*'*'((!*+%'(!"()!!$"+($)!+%"+!+!"%#+$!%+*&")!%()&*++*%++%&#&*"*'%*$+&$(%&$$$('"(''$$("*%#'$'$(*$
@r5786
TANANCAAAACAATNCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCCATGGAATGGAAAGCA
+
0&$5*::&,,*A!B<<=2.3/*<.-!!,#$"9E69@?(%CC"'9D:3)?3B:8"D#A;*%!,:9G$#F04*B984#'&.424E,
@r5787
CCTGCAATGAGANTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCT
+
%$&.74C7?%#%F0(9+HF!*&&;-E<H'4"0>A$!H>"$"2(5(4B#;802BBA"'><.D7.4C(%5C
@r5788
GCATTATGGCGGTCCTTCAGGGCGCTGAAGNTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCC
+
F9>#FE!D:=%*01?E)GD>F.#,B#8;1/768A;:E65-?H*E(6,<;EH:$.:71>&2,)2<F+*<$4&(@$@&;@8H7:HG9,B#%"E8#="+1H/.DFD9)E@F'$65#DB3@AD4"G?2G(*"$))7%#2G??,'989009);2698H)'66-!HA6
@r5789
GCCGGGATATCGCTCATCACCGGATAAATCCNGGACTCCATCCACGCATCCAGCTCTGAACNCGGCACCTGNGCAGGCATGAA
+
50&:(*7=;*<6#?D-$;A19<,0'9&F<78,91/4C02,!39060'C/+9DA-<775(C%#C-+92@@#(7F5@,!F650!1
@r5790
CATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGGCAGTGTCGCAT
+
'A;"58!0;=038((=+>(!B++%)5GAD+61".9"14!@<8:5C*0B.0DH)(G?7=02(=-'52/,F!G3
@r5791
CGCACTTGCTNAAATGCTGCATTGATACATATTTTGACCCTGAAT
+
6:<6&0DH@21E#2<4D4H&E*'?0*=84/)6/+-2-3+"E54BH
@r5792
GTGCATTCATTCAGTGNTTCCTGCCGGANATCCTGCATCAG
+
F"='!G*?C:3/;B;5B6-.."44&48DC@2@?+48D=08+
@r5793
GCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCAN
+
-E(9G<0<4C2,)F?<51F."::*<E;$.%#$?/<9A+@("6";2*.:?E-5"7/A9"%4&9G9-@+E3D-,>56#,;#268+!($,%;9'"
@r5794
CATGGGAAAGAAGACTTAAAAATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGANTCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTANTGGCTTGG
+
2&,:7DC'>'D>5B47D(($E6+C/+!65;('334D-%1C,&*)**E>?ECDE4?B?":+%9;97H6:?=E$':B%+%'#8G7F*2H4:$@C@A;$:/2<&%-,9B!+G5A:%%5->4;=%*&=@;<ABC*!'3?"-B"-#;&*#%933%:97+>$3+DC/45>7:13EG%?7$/26+(>H/.8EBC%G7=(2=<"A.F5$#)129C*!'9-&<+08/<8+
@r5795
CCAGGGCNGNNGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCA
+
###()*)&%"&+!**"!%&'$*'))'#"+*!%($!)$&##%!)#)%&(*&%$"&)"')!*!$)'%%&$*%()'&*+)&%"((%##$
@r5796
TGAATTACTGATCNCACTTGATCTTTTTGCATCTTAATGCGTTTTCTTAGC
+
+"!$%&&'"#*'!+++%++!$#("#)$*(#)&#)+%##%*$#&&%!%%)*'
@r5797
CTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAA
+
31$9,@D5D&@>"+@CB>(7A.3DD';2$G)$A+2$'2'FE=!2'.H=*6E%?-=*5#*H6>$2>DHG<'.=GD.A"B@5?!3&)/'"9?:A@;.$5E.29B$++/-+G/>A=-.>33'&<?F"!6&!B=7@)!*0BBE,)H(0D5"
@r5798
AGTTCCCCATNNNGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTNTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCAT
+
!"$'#(!$'!$%")+&)"#*#%''$)("%#"**")+**#*(!'(+$$"$%#&++!**"$$*#%"%+$)#(')%++)+"+&()+&*+)(#$"!'')''$)))"!''+)!)%!''*
@r5799
AAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTTATTACCTGG
+
%:3DH/C50.><B>89!".2>H#37#8D551(%)*82#>'%-5"BG$=
@r5800
ACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCG
+
>E6"%"A)@=A0A!);>!&4=9,,72D=9"<#!GD*%*G-8.DG77/$#A0'C/3$B7>!3%/01:
@r5801
TATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGCATCAATGAGT
+
4'$74G&26=!;D>,9(!'>F&B.@+A1&!=;3D673-8<#<(GE@$*E7!.)@E@@:=DE,7+;&ADE.>B*).947+#0752=:$@(,ABH=83H34&726E+>.$3/7@24D/<:70B,9):03"/F.,=-%&#.?<3(4?-$+5.7*3(:D8(86%C(*@)3-+*!@/*9"-D;BDF=,CE)A24#,'C2>+08,@(>2B'0,=D99,E7!%B0C+;.5(?%.BG.F!#5+C<@!4.<@<4+;
@r5802
GTGCCNTNGAGTAGCTCATCTGGGCGNAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCA
+
&*#$$#*"++'!+&"*(%'!*$*'+)"#%##(&"$&"%$%"*)*#)$)$'+('$!$""$**%#(&(%%%&)##'$"")#%*
@r5803
CGAAGGGTGGAGTTTANGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCA
+
"&)$?4G7;8@+)F3>.$0,$7<'+:@F(C4</75C46();C**F2$463@HE8F=$199F67DG*%8
@r5804
ATAAANANGGTTNTCNNCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTC
+
'('%(")!#'**"*'!+&'#&'&"*%##!*"+($#'#&$'&""+&'&$!"$#(&&+!(!&&%""&)*)&$)+)'!
@r5805
NCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCNTTTCAGATGACTCACACCGGTNTCCCCGCCCGACAACGACG
+
&$'+(**%)"'$'+#"%%$"&+*"+%()(("")(%#)!++!'#'#)(&(($('($+$%$'&(!##!!&($!(+"!!$'##$%+!$*#$("
@r5806
TAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCT
+
##:G+GB!#&B?/)G=,<4FA=A7E+%,-'">:C$.15F"/E14%*@+*
@r5807
CCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGNACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCA
+
221*2>))8!2@/E-6;6&(>*%A"*2!A'8)G-B)%<A*>560H'>+G34,D/=>.F($D.<23)GB#C@6>&H&+6>!68F>53<HC!8/D4?*'-.2C0G@!:>#%.."<:@3G1:1%B<18*'$A9>:99%##@#5&D8C3$&!=G'32?F?814A+)="H=710?A::5A&8+9=HA.'A/1*>'*F9"74(FE=@B@)9<E&@
@r5808
NGANGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAANAGTAANAANCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCA
+
!&###)*+#+$$(#)'++'+$(*"&((*'&$")"'&&"$&&'%("$$+%!)**!+*$$)+&'(((!&(**)'+(&!+!$'&*(+*$'&)+"&%(#!$%(**'"#+%"$%&%''+*)*+&$%#!'&)%'%####
@r5809
GGCTCTGTCAGCTGCATAACGCCAAAAAAGATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTANATCAATTGGATGGAATTGTTTATCATA
+
,3=,6<01(!<F+=3'%839C94)$.@4-94'!5<#:$D#!C$2#/G4-:$/4>,1&HF*'1$C7<2.A><9?3@9<0?B*68%GB!$'C6#%*H,
@r5810
AGCAGTCNGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCAGCCTCC
+
,G84E#;BG268?D=8B6?GC/45B-/?D/6,C>$0F+:D@8-)#//&,$0$%5*$DH@=8
@r5811
GTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCCTCAGTTCAAGACGACGCAGCACC
+
FD<+G=:/?H*5>F+@&F874,,6<!BF4&=&1F(<-#'1-&=(7.C&<D&7?(-;H7F%-58;@38394A-C@78
@r5812
GCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTT
+
3G3(/G$"7*401(+D*./)*$)8HH9'+,15?7*@EBDC7&&'H*/>#5B*-+CAC(*
@r5813
CAGTNCGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGAC
+
'%!*!%+&+)#%$$))%*+('$)#+&(+"(!"*&!&#$%*#**'('*'%+&&+*'+
@r5814
GGGGTACACGAGAACCACCGAGCCTGATNTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGTTGATATATGGAAGAAGAATTTGAATCGAAGAGCATCCTCAGGATGTGTTGGAACAATACCAGG
+
)D,B8F5-D'<A'6/;G(FA-=6,&C@/2A(>-BF1$69!;9,#,&!$2%088!($1.EH)?'<C!/%<#09/<'*%&7H!.&6,:896<3-@0.-*#++5=,D2D%D<A+&=C7&.)B:D"0&G8:E2"/6-D73.:<D"
@r5815
TTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAANATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCNCTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCNTC
+
6!GHC0C6D6*H/0;5;*&+,*;>E3-EE?<0H+">&!")?CD*(',166G!.E"6,@6*C+54&B4,.9*D?"D&/D7((D2;3,>DE@"5/)080')5#9,==%!:60(#)@E:8E1(:<&D,/E>5<C&G!@#@&7#;,.#G?0&:>?1*=+//C40>=>HG@E#HG5=")2;F7>16(13
@r5816
TGTAGTGAATGTCTGTTATGAGNGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACAAAGTCCGTGGCTATCTATCGGCTT
+
3DC.68,118+'#F!+F/,DG3(6*7$?B7/4;#F:4>+"0:,9#!20&%)-(33'*G:C8+:G5*1@B'@F/'/9<,4585>,
@r5817
GAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGNAGTTCATCGAAAAAATGGACGAGGCACT
+
?;G27:DB67?'9D#!>3C-?A4:?0F#7E<E'0<+E65--&6$-8H>;9&.7$(D<H+"!,D1*B;HB)+EH3
@r5818
GAAAACCCGCGCATAGGTGGGTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGACACTCTTCTCCTCCTCTGTT
+
+:8%GFHD5'%2#$,(53FH;%!5574,?02.:B7'+"(+35+5=FA4H'6>F6"=95:'77@72352*C=5!")),2F-45*$E6(3'G49/.H1D>5'G?G'
@r5819
NAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCAGTCAGTAGCNGCATGG
+
!0?65:667:4*&7)5%@=BA#)%</@%$(E0(-5(';(2./*FB;>08E;7/=7#)-&</1>89,8C*&87<@,:/1(/92#D853BEA12*)'1>#'=GE9>67'#BF">%!"HC<;!)4/=>5*B>$"?=+-<!4&E9C9.;($<;@#;>HA*;-%8"5!@DAH;8"84&5B)),6G$00F8C7+>436F&!)03E="#:,H)@"+3F(=0
@r5820
CAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGAC
+
=6:"!=0@%02#5:"5'F-74,82;"$+-(@'"@&8&@(B:?2(-78BG)1+):&9=
@r5821
GAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGC
+
F-5C.:'16G+(C">)CG$C4#BBG:G.5'=A%AG*B'0"G:C,:%1@H8@B9,('B04
@r5822
GTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCNTCTTCCCATTTCTGATCCTCTTCAAAAGGCCCCCTGTTACTGGTCGATTTAAGTCAA
+
#*((+##!#'"!#*'#$+&"'+'(&%'#+&%"&(*""$!&*!!**)%#&''#%"(%*)$"#"$*$!)$(("+*&!&&'#%%*)%("+)+*%"$
@r5823
NCCGATCATCTATCGCGACGTAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACG
+
05?<B:-%:$@<$"*9#CE8&!?2'38+57G:$6=66/"F#";B01B.-')?.!0HE19)C&:8C
@r5824
GTACCNATATTGCACCGCCAGATATTCCGGCTGGNTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACNGTCNATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGG
+
%+(%%#&'*(')%!$"#*(*'+#%!(+%$$'""+'*))*#'("&)%#+!!#()"+"'##!*!"%"$!*+%"$&**%$()&("&(*"&))+!*)$)'*#('""%(%+&#&'$%("*&"**'#$"""&%%($%*"+$*!+&))))&*%)$
@r5825
AACACCCTCATGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACATTGGGGGGACTGAACCNCCACGCTGGCNGGATTGCCACTTCCGTTAACCAGGCTTATCNGCGCGG
+
0E%>'"H38B5%$,G+%;('.+@/@,H5;3<A&7/BD:F2/=H?=&"1/<E#+@!E@C;0*@!%?*E>A>:;:78C#5<0$?%:6:2;/501*11@C6+25)CFCA?:8A;59D
@r5826
ATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAG
+
9<.A68;H+%:"?;(:<*6315">82#58=,0&<<>+7+96@25)'EH&2%:5%'869&.#?;
@r5827
AATGCCATGGTGTCTGACTTATGCCCGAGTANAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAGCTGCGCAACTCGTGAAAGGCAGGC
+
+</>?&62C6A9?6;'FH%,<:*>8"<?&G3'(=$.D15*!:6C=,2;1<(09.G#=EG?B*&C/3@8C<!E*$>=@.;H476H0HD(A!!F@F<F<+H!-?%?!DA3,'
@r5828
ATNNNCTATTCNANCCNNAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGNGTTCCACTCCTGAAGTGTCAAGTTCATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAG
+
)&"#!)&"$*#!))((#$+!$$%"$!%#"&)*'#*(%$%"+!%*'*&#$&$')+&%&")(+"!$#$*!$$)'*)(+#*")!%!%&#*$$%#($(+(''+!"+!'#(+'"#*!!&')#($)'*+$+#&*#*#)()#*+%%+!&%$)$#!%!%+$&"!!%*$+*#*'$
@r5829
GAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTCTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGNAAGCGGCAGGGCTTGCCG
+
HG+"%9E!&*;3$<C+#00?E2F7>0E,%"$:"=E/=F8B+7<("!F+'2076H%0EHE%;*!-('428=/@:>1->(")E,E9?+C4/4?B"1B"0G$>"+A4$3-9$+&&F4<,FD?=3!:C:G+-=.,,?64,*8@G;4F709-#,7($"#8C-:($+2)/2B*+?*(:0*@.=?<@;?F;H"AA%$?'D3-E&&&2,+>9+8%-)E9
@r5830
TATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGGCGTTGGGGGGACTGAACCTCCACGCTGACCGGAATGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTC
+
D&1($2+?5E+5')G860=CA:4(%@!A8;1BEG<"8C??$A-!1F-8=-&"=+0,0C7?H";>4?)G7A/C*%@)!H?+97=#7&C,C)*56H2!#<!/@0&@:G72980''0"CD%1A*0);+"B.E#:%?,*6<'F&:D;*!A.
@r5831
CATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCAC
+
55(H%F#G)/./$!4'/4>"GED4/%)1G@8'=>">&23.6%5-;
@r5832
ATCAGTAAACAGTGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCAGTGCGTGAAGCGGCAGAGCAGGCCATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCC
+
*6#A8'*'4'#?,+.?17E32(@<%$->38:6-<'$*AF7D<*3./36=%/B9!GCH:E%'::7>8H%/GD*(G32'934**+-103G"8?$6%>7;H.;683G63:'/7H%3C7,D;C;B%AD>D3/*/B,=:;-.H@F5!)8:=7*#/C22'.%120;?(<,)";%$#F9<@37H'G*G9?
@r5833
GTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTNTCTCTCATCTGCT
+
C=,4%$F$&BA5F$H.H:"A==++&)!E'D$,"C>/2"H>@+'1C21)<.1E*5=#7/GF>>1#5C&%G+:/7D2?"<&2)&G(4(*%2#H(8.E7@1(GB%4)=+6$74.+!$+(5G@?0.=')B>%9<?5A+!$H73=3(2D3%4"<<%DB/#++4)A5)*2"6:D$9H,45:5(B*$&%!$2.**.?*81(D>93"4('D#47G!>H7-&'6B99D)E?G*(>:@=EE)D67!=2F$7$;?7
@r5834
ATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACT
+
(27;3)/-E/G.-;A!E?=)0G#"@$;A;=C%)1F20"-!A3"<8!?8;(H#E'%#&%*8
@r5835
TCTGGGGAAAACAGTNCGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTG
+
++;F#1;<D8#..G.G*+BA1@E.@*!$60,E621,G"F"*.=*G#=;>E1GD;$/$-1
@r5836
NTTGCTCANAATAATTGCNTGAGTTGCCCATCGATATGAGCAACTCTATCTGCACTGCTC
+
$+)$"+'$&$#$!$+$"+*)*'&*&##&"+($!&"#!'*$+*$)$)+%$)$"#(+&"&+$
@r5837
GTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCTTGAATGTAACGTAACGGNATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGNCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTNAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGNAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAANTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGCAGGTGGGAATATCCTGCAGTCCCGAACCNATCGACGAACTGTNTCAANGCTTCTTGGACNTC
+
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
@r5838
GTTGTTATCGGTGCTCATGCCCATTCTTTCAGTNTTGGTTCACACGGACACACCATCACCGTTAACGC
+
@98'>C)05/*8DD<F<>#693=/A@&:A')?E0.G0-%!B,0F'H=")9=D3+&&/G>$//"&?+.2
@r5839
NAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTNAAGTTCGCAGAATCGTATGTGTANAAAATTANACAAACCCTAAACAATGAGTTGAAATTTCATNTTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCANTGTNTTCCCGGNTTAACTATGNCCACAGCCCTGACGGGGAACTTCTCTGNGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTNGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTNACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCN
+
!++$$!&#))'#"("!'$%$*+!**'$)$("'+$!(!$#$&++&()(#%%$'!*%!&%()!$*%%#$&&(("+!&&##(*(*+$")'*$&*&(&'$+$#('$*#$"%'!#!+*)%+$+"'!+(((*'*%"&((+%(+("#!!+('"$%%*!(!''&#(++*"#$$&+**("$($(()*!'&"!'&&(*%#(&)"%"'&'"!&#$$"*'&("'$(&+)'%"$''($#+*$!((&$#"%#&+###$$)+!!)!'+$%*+!&!&"(&*))"+)!*&(%(#&()()%(')##'+'"%#%(+!%!&'*%&%%)$("'!&%*"+#+"+"+#(*$*))$$+$)!+#"$$""%'#!'%*%&""!!'+''(*#!"%"*+)++!%!$$!)+!#'"($($''%%'*)%&!+!!)%+%*"&*$'))+$$)&))!"()*('+++&$+%!!$$&*#$+*'!*")*&('%&*&()"$+(**(*"')#"(%!'&'!#%#(%###*
@r5840
TTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCA
+
3G,3HH3"??7#(==*26*B1=%5#)3.%>E.<BEA3!<F$D!72+C.B?H8,D-<848@;5C!3?D5.)3;2=3.65+G&&*C45=$1F3$$/';>,H$#1%E2(+0178B*!*7<+B)3A.(?8,(5$$%BH'"99=92+>@62$33#2'*/@&1D)E0%29"4**
@r5841
GCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCG
+
;<;$3E=!#&D9("%7)<&0+&HD&60$92G@1&G.!7.?6@$.%!>(G%2F-$:7E
@r5842
GTTTATCGTACAGTTTTCAGCTATCNTCACATTACTGAGCGTCNCGGA
+
#1;%4/G>.!/BF%@(/220A"9<,3-<=9,;H3=CG58!5?*;)4:6
@r5843
CGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCNAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTT
+
<A58@C.)B0DF3B5%7$*"/)',7;+)1!:CFC:32.&1GF;95"-(B-82&!GD8"=<'<C19GD"E?('-,9;"#>2C2":*59F>%'"*GA/*=.918)&(D1@:@>-/--9
@r5844
NTTAACTATATTGTGAGGCGTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCAC
+
!G<*=%%=$&(2?/5E-2!,5<?ABF70%<*D%F)5>>D3>9H&35&8HF.2*81$;1+:(!!.A%/:=A!C9/%/",:;HB;')=DD80C9",<8G(H!;3(6G/,'AF/3DF9'D$.!&9<D!2>EH?6$HG,?A**;3G)0)GG#F?)--8H)/*9")F218
@r5845
AGTGACTNCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTGATATCTTGATATTTATATCA
+
575)>E#&G02?2(?>8>8!63!#D448H:E2C.),,(!H7:1=8@%F;E147&6?B0=%8775:(?0<DB+,9A>4%',G1'A
@r5846
GGCGATGACGCCTGTACGCATTTGGTGATCNGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTNTTCACGATTAT
+
2B,*8";,#D@<D/.5G<)FD50B,A<:3&A=11*?9$C-6C;3*:<9"/7'4/%1@@/."2E#B%"6?$0D34>:$>/CC&9BCG)1C#/(F<D$&H#56?#CAF*+G;9"
@r5847
GGCNATTTTTNATCTGTGAGGATATCAACAGATGTTAAACATCAAAAAATACATCATT
+
&"))+)('!!+&(("*$''+(*%%!*+'**#!$*"**(&!)$++('+*+('&"&()!$
@r5848
NNGTCTNCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCNAGCTGGCGTNTGTACGCCAGCGTCTCNTCTTTATGCG
+
#%"'"(#)#&++"'#)(&'*$')!"$*&%'$)&%+!"#&'(&""$*&&#$#$(&*%+++#'%"*'%***$"*'!**##$$')(%+)$)!$#!&)&($$$''#%*)
@r5849
TCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGNCTTACGCTGTG
+
H4'$A&5+1,)=D5699(4*,H5!($(+F+32+#?":7A)=93;0!21!,9:B4?6>4G02>+*8&
@r5850
TCCAAAGGCCACCTGTTTCTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGAC
+
*:;?E>*1,0'.<>?&B;60&"&%0AE!6*$'>1%G2'H46+.A8&,3.30'C?H/?"7+/H/,=94.H+-7$6#-?&;!-E+HAB(56/++"$0CD"=@5/@'G1?H$'&1+'%+3-&G8D:>.@B=2GCH/6<:#C.+1EH*
@r5851
CCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCCCAGCG
+
%)&+)'%*'&&'&!&'"&'*)))+**"""')"#*!"*#)")$'')*&$
@r5852
TGGAGGCCGTCGGTCGAGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAA
+
F!7,?4&=G,F@24G2A5(3"3F,56$%'+4$)''@.9435A+-5&6'1G:/?8F+)*)?H8+4//!:%7;;C<%$>="<*%=G>9(!FFG:3!5B*%
@r5853
CTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTNCTATACATGCAATTACAACAT
+
G%-D#&-;60;D,AF,:C*?=3D>0B5@2'D#=6'B16/A,7F,GFC.6+@+$4-0<+#%@'E!"F!+4(,:36
@r5854
CATGANTTTTTTACGATAAACANATACATCCAATTGATTTA
+
'**!&!&&))'*&))*'&((%('!&!+"&!)!("+*'&&#'
@r5855
NNNCCACCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGNCTTGAGGCTCAGAGCTNGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGGAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTAAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCNGAGGTATAAAACGAATGAGTACTGCACTGGCAACGCTGGC
+
&$$#%"+*$#%+%"$%()#!#%%"')#')("!**#+$&!$#)&&!#"%%$*$("!*'(&(+)#)$$$$+*+%)+++'*(*&++%'&()*&"$$$!*"+"!"%+((%''#'%+'+%)!&)&!&!*(#++*(+(($)#)#"'%*(+&!!%'!('!)'&))$)%+%(#"())#+!('(((($!&*'+$("!'#)'$"(")%$'&+"*(((!)"%(%!'&)%)$"*))'($**""')+$(!!($%)*#)#('%)&)"#%&("*'#+'*!$!(#"#)&%(("!'#'#*'+&!#!**$!'*&('"'$)+'**$%("%"'")%"%*##()+#"&$)$'#""""**#*+)(+!&+(((&""*&##+!&"!$(+*%%)+&++$#$!'$()(#"$"*&&!$%+&#(#')'+%%!'*""&
@r5856
TGCGGATAAAACAAAAGNCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGT
+
38BAB'"D74'*?!4)&<!4.27D!6&.F=6H4-F4-G%9&82'3)-2F;CE'6569:7EC$H**.7,3;1?,?(-H(F':)H@15'E7(?:,%"%=?6?<-1!0=-%<F"A:)0/?$/9-E)(";@!>8F8C99%.:>=D$%(H+0E/A2F"?F@"&H.=+<6
@r5857
GTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCG
+
E40E'.C>16"!>'"!+7:86+*&3CD820&%#F"H+>)8!4.+>1%?!90F$'%619D3++21)-4:4-$73F:.-@BGE5,EH9>/'36=4:)="2F%22
@r5858
TCGCTGATGGCATCGATCACACTCAGCAACTGCGTGNACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGNTTCCTTTACCCATTCCTCACGNTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACA
+
!:3/"!)#$4(#=D6BD8-:D)B$)H41,>,=D#49*#87*++48852229)"G$.<9,@%7!0*02%.@E155+A+&0>C$G9-G4B(=,)7D,E?C8>7"6DA=57B>0F@FH*!EH<':-D-(!;+D=1A?B00;>,:;'=E?86
@r5859
AGGCACTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGT
+
+;54!H*G?"$0D,6A)#:8">C850A$+"!F?-4*#?E<.6;9</#&:7?05.,-.(#G/C'+6
@r5860
CTNCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACA
+
227+H9,@;(3D/B.?B(E$*'48>9(!*<%D94=)C?$*<9@5;>'<"@,*$/=G0@%*@3G+.+E3!--54+4"#$3(8.>5?<&D-#5
@r5861
GTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGNCGATTG
+
(0;1%A&EB'2FG9:GDC*$;G6)HG/,*9,(#A+4=8&-B/E>9/B,
@r5862
TTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCC
+
%G9)3>7(E;%+1?:A#?,F4$"05>D*D%5+$0716(GD/-6A%C-B:B733A3/"C'"@E94#9B,('HAG,4C5D'&8.%8D-0@B/-.8*-+)FFD&$*CDEG$;F@?G;ED;>/G+?4"9;$/6E/5>4?H-E'4=9'@B!,"5-+D*&/;/(@%&!+9=!C05B*(HD*63>C833A='*F
@r5863
TTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCC
+
GF3.G!)#*:!<23:B3,:'F/D,95@D0;2&H+G@>=9$<!'>*2=;:.>:D((;&-1-?'B385CB8EA1HBA,G=>..8%HB)
@r5864
ANAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCTCGGCCCTTGTGAC
+
92=&(/G&/&2.36BG(,)B'B@<:EE@G;;/>5;!#D!'7=ABA'?9>/!#7"/#E=-).E&267@E/'31/93
@r5865
GCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTAT
+
,%7:62-)4/#*9-"<B(E*G%!";"F*8$&9-43,)E://.A&,G:90#9-,&H.55G31*<!2+1(70)A84H7)==A:4(&!9?%-%>1A<)+E=3&>+D36D8$,9!.:H!'E>"?3:E4;!==&
@r5866
CCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGNCAGTAAAGATTTCAGGAGTCCTGAAAGACGNC
+
5(>207.H/3D#H>=(0)''FA5E68'>A5*1%8,>61C,:7@6229!**;=.70894H,C,.8E2$&.*&.
@r5867
TATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGAGGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAATGAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATANAATAATTCCTGAAGATATTAAAAAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGATTTAGTAGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAA
+
+$'B37:.6+A93(<84-A!A7:H"9<AH0;8D$A,596'=B)D)?(4=E'8<')6)82>4DA!<+E0#;%>EB;7=)*E7,.*#-'+@FF5;4*%70,.E/2;H?<-1%F"$@;."#%%@!3741:EE=)C)5@*$G:;3+@$2";+9"%2)<(!=%&';H*G7$)+@'08*$2<)+F#:.3:(B.+$-@41*"!5#A;=B9.$.-<*;?C52/>%</(#!@45=&*!9C$>";$3D.B((2F"?<4&%D0*3+5E;=>2%17<FDD-<$A9/+-"(:/HD0F%*;4C0&>..G&9H70D%.FE8%++,2"!6;$?D=2CG50E=9,1@5>C(F777B*>5"F40*?BF&HE,)H.;H:'+C4?0!C4!)9
@r5868
CNNCNACGCGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTNCAGCCAAAGGCATCCATCTTCGTAAC
+
%""%&*$"%&+&!(#&$!()(!!!+')##("$&'!!**+($%')(#+($(+!)$&*!+"#*"&#"#%")%*'%)!"(%(#)*+&$!+&'#**%($$!**"$+'!!#*"((("'+"*+*)%"&"(!$&(&$)&)###*)&+($*(()*##%+(#'%'#'&*#%&#%#)$$$$)%+)!(#%*!"(%#*#&$*(''!
@r5869
AGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCCTCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGNGTTTAGC
+
+)+)!")!!&%!%&$%&'#&$(#*&(!##&"$$($"%%*()(!%$%)($*'()#)!#''!+*$%#**$'("%%%$"(+'%'**$'+*"+!)+("(&*%%+%'"()(*#(%&!#("&'!%(*!)+#*%+'(")$%$&(!&"+++&))'%%*#
@r5870
ANGNNCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATNCTGGGTGTGGG
+
*!$$"(+%##&#%%)(%*#)*#++&*'%)$&(*(+(+*$+!)#!+%)#)#!$!%#'%)#''&&"%$!"'*$
@r5871
AATTGCGGTTATTTTAATAAAATTAAGGGTTACTATAANTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTAT
+
H("1D#13"1@G1+/"4*2G;/7<+6?"G$&6%*78D$A285';..",D#)$<B3'"%72(H.5F5/8>&131?!&@G%FE#,&D=G2-3,*F=,$..>)./=$%*;<63$G(%D%:<?A19%8B-8G$
@r5872
GATTAANCGGGCCGGGAATACGACGGTTACCCACCACAAGCAC
+
$@F=>H"+9/#-232H#5"95ED6+782?GG..E'27"CB=8E
@r5873
GTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGNGNCGATGAAACGATACGCGGGTACATGGGAACGGCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGNTGTTTTTGATGA
+
@9===A0-(A)"F>=+GE/=4>B)F20*C3)(09G<</0H0F/4-"%610=B3'(G;->C8E>(<9F'B?$6E,86-"'.G.BH.%C>5CBF4((?(0>!$3@F-&(291E4$@/,C,+C(D57:)G0!2&(4-#6'A60-)>EB=6#.F:56H2;20<&121.>"'+!A?9?.F34%2(F".-6;:B',
@r5874
CAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCT
+
;):EC(3=,@D,:?#9C(EC24A!H/!A;0;)'/-C?5,=%A-<$!=#9-?435+"=FGFEA5.(=@;47@C+.A**HE84@+&'
@r5875
GCCGCACCGGCANCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCG
+
1:)&.!9>"#*H2B#D/;H"&'3>'(<5)7&FD0D%./?>*H#">HHEC"F)>,5!=A7*@"?.G,G$)>011?=>F$)FA88.*#/.0.A#$@B1*2B*/"<22AD:EF".%"<<2."+9",4CE<0D2H<B178)AB%.DH-G-D3+!:),<B;<)
@r5876
GTACAGCAGGTANTGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTATC
+
F&71F'!&H,(<)8>$')#09.0D+H11.A@4;D9$4(,!;#1C0629?4-(0C;A)97B8"&8'H5!=G4%)8F
@r5877
TAGTNAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTG
+
<-488E)@=(!'7$$7*)(.*'C<(5G+970,"1HG<1%F<,49<'44.90&2&?C56?)*-0!H41=<1-!&A5A1"?$
@r5878
GCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATT
+
F?65A7--2C$5(=88$66565;2&*@!2=;<?)/=1!)7
@r5879
GTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGNTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCG
+
>+4>C"<G8%'?>$3B&(7:51&BH'B#)>"B9(52>*>3("B-10DDDB3C68EB(E/+?4/6?/191H=B#3%H3C73<>(D1)H@2B,@%=>=:+"!',:>&>5/(%@401&%H0,/H"4=A?G@G,9F5:1,A6513:(B7"20<F8B7>!<"G=4C$.F;!0->F=<6:B2'6EB?4*<G8-F7:;!/D)?(-C:=$<A
@r5880
CGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGANT
+
7AHAH54#/9G;-/B*FH.$1*>F.3#536A+(3!AD-%86'-.#7#03)B$>3F1#D"$@+)-(D36A#92$8+/-
@r5881
GGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGNTATCTCGATGATGAAG
+
D<';F@5C8:3>7%B:0>%HH+)EA:@&.!"-EF*DA683?(!E2&6@#0&.%$/G44+1C@@29:"9)H*3((.?8B<#.1$1"B<?)</%1"A0(%9A%-A5C=-3-E)9.>+=5$:49"8@2%F0'F7)-$=5'
@r5882
NGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCC
+
%'%23&:6">(*G50+'9:H;**E9'9,B;2$$>2)#75.;C($@>$)>1@*2#%/)$%=:9:$"#AE)(-?2(86-
@r5883
CCTTAAAGCAATTTAGGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGC
+
98AE&:'9:!@<F73>+>AB0DG*FF<;H*'5$>>'(*)*2;?:<4H;C3@-/&/>/@?18+(;!EE&G4)065'05D!=%C:=(.!'6;<@3"::9D,-<9@3H>(21<1,D/5-$4D>/(<F5G?C",?BC@'1+1
@r5884
GTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTNGATAAGCCTAAAAATATNACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTG
+
/*903A;'@(8.HBA8=4H,-'9H-1G,EDA#A<%:(3H)2**-=1?83,?)871F92'3>3>5=7><7+=0%H-)*+>.@#AH)@<1==*!4;:#"B#E>(.;55&)+F$)>7;?,"C'5B2=.-D5
@r5885
TTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTT
+
.D1?/)0D;:E43@$23,HB6?/0(0!$?52H(02@1)>#1#6DD(>)!
@r5886
ATCCGGATATGCATCCGCTGGATTCCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGA
+
=D97%:%44G"+3:.0?E(#*?0=1=C>--30$+D)8(=#,D+D,%8G,#>,F?(.!>89'02,4*"*%A$%8%G#-C@-*?ABEC).G-/D5+GC;G%%6-*'
@r5887
TTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTG
+
C%E"3>)B(">"*GF?64<5FF!?-&..!3*#B!(>&77*"
@r5888
TNNTTATACCAAATGTCATATCCTATAATCTGGTTATTGNTTTTTTGAATATTAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCANGGTCAAAATATGTATCAATGCAGCATTTGAGNAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTNTTTTAGTCATAAAACTCTCCATTTTGATACGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGAAATNTTTAATATTATTATTNTNATTCATTA
+
'%*)+")#+'"#$&+'''$"!&$&&!$$#)$%%#&%#$*!&())$#)&%&*!"##"%'"+'#%##'"$)*'!)!$"()$&""+&&$!"#"&+()*&)!'+!&(+'&!'+&#"'%&""*('!+%!'!((!'*%*$'"")&)'"+!**!&!#"(#('$+$(!*)$!#('#"%!(&#&)%*)'&%!%$+'#*()++'&&$+*$#"*!$)'('$%)*"&+"#'#&"'&#"#)*%'&#)!+!)*+'&!'$*%')&)%#($!+")#"($*#$")!&")$$&$&$*%+"(+&'''$'%(*'%*#)()'*'!*&#)(&$*!****'(+&(+%!!&$#+*#!$()'((+%(!%("(!$%*%%(&'(&%"&&))(!!%&!
@r5889
CGGTATCCCCGCCCGACAACGACCGCAATGTANCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGG
+
0.)">7(:D;.0&?;?H!3?#4(.?1630A462A(/1/*3;7)-?D1?H30+.D.8$-5/=3.FB(3*<.225->5-,H1+F&8.>=A8
@r5890
AAGCTATTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTGCAGACATTAGCCTGCGGGCCAAAGATGAGGCCGGAGANATTTTAACAGAACATTATCTNTCAGAAAAAGGCCATCTCTCAGCGCCTCNGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAA
+
!(%('"+(!(&+))*!##!#+!+&!"(+#$'#%%&''%'&!%'&)"$&&%)"%$+($"&&$*!"+$#$()#+(+'#$("!#%)'"!%$"('&&&$%#%*#)*%*#$##$")*!('#!+'*)*+&$#')'#*$++&%+##)(!!'%'*%**+##%#!#%+#('&!(!("+"))+!$%!*$(''!!'!&"%!+!)*)*%##('!)$&'"#)%+*%#!%''%*$$&$#'))+)+&#*"'&#)&$'!''+%(
@r5891
CAGAGAGCAAAAGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTG
+
A9@&E>FA5/$>D.4>%AH2H/G*!=:/*4B<8'17"2:/%63*=#A*:D/"*12?1G/,EE'@;**<6=-.A(=(:8E+H#1(%!.9=#1G);.>8%"6(1?&(
@r5892
CGTCCGTTATCAGTTCCCTCCGACCACGCCATCATATCGAGGAACGCCTTACGTTGANTATTGATTTCTACCAT
+
+5/!9"<A3+?1AC'$%.5+@5)&C.A*).-#5@7$E1:<'("H"(&@*!&&%?)>57%.G1&/B2.91C10#5
@r5893
AACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTA
+
6G*6D@1E.EG6D:#7$&??63<.A'B>%6C"#9G<F+0$!C'D0C"5<.:!C"$/$0888%0/01,;*
@r5894
NTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTNTATCAAAGCGCG
+
"6,(1)4+G*=82H</?8).+C+9?/17B-)D3@'@=&,.,&7?$:-&?G7=;H"@;)E4?!F/"'>&>@H<H+44BB3.('/8<<?"AC=;<6';0D+;"B"(9&8@$E2&1)@!*?&*>9<9+
@r5895
TGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGANGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGT
+
D(.2-$3+C,4H>&@))"D$.GG.(??0349"+5(3'*)C,:,F#C4%53-:67-:'$=@#$6;CCH?$<+7!G<A)D:=&GH4/:D:-$+<04.>A#0)A'$-H5E7$),4&73',070<1"
@r5896
CCCNGGCACTGCGGGCTTCCNGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACTA
+
D.1"+.&<%G1:<@&%;+#282$*,1:)3#;,A1@D1/?%)B7&0G796/,6>")/9
@r5897
AGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCNGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGANGGCTTATCAGAGCGTGGAAACGNTAATCACTGGCTGCTTAATGGCGGTGGCNGGTTCTTTAATCTCGATTACGANAAAGAA
+
/&(?&.>0?$$@A/)>"9@*=?8"G%8:=,-+A67C>%;4?GC<;CG!G3<G!-)B05.?$2&')?8.@D;.<&G1;3#71E?(.,>A>B')6',A>&<*1&9#@FB/""93#-5(GC@@*/)@.2CC/??B/BG4H!C6?*D/C)0>.H1;1G3E7.8(FB*A;AEHG1,;:90HG?(1@#6-98'@92"6C=!##+2C*#19?
@r5898
TACCACCTGGCTCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGNGTTTTGCCCTGAAACT
+
=$A"1-0/C/",);,!)>50"!;,:"<HD6#;A3!$''/<7(9*(.0>6C.-8,#B<B(H%9$$?91(<,<!,3+6074-2434/8H862=BG38AH@:C6?7.%66FGA%G&33867/?F$&3=+>/;G<AG+-A.0./;$F<&!(3')7592;!)B3#&$38+695D'4!@D2
@r5899
GNGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTA
+
'$=3#7.%=DC2(3/+*;1",1&;H$-(0CF10!+9E(F,@@>3!#)<11#5D%*9.5.'F:/"HD3:.B091#G8A1>;%"0)=/7@31,/).!G9;D+
@r5900
AACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCANGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACANGGGATGANGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGCTTCCTGAAACAGAAAGCCGCA
+
HG=9(%H*&B*,7"154%6E9./%D/F/(/%14:1A<.8@!=?."B/-/5C.7A?:&H!</&,5>14%<%G:>-E<H643'0G'$87"G)2?C4%(3D++.+!?B6@?3<7FH>D,2F45C.B=<H(1G=!(),@GBB..8G"0#<159#B8,3>!.A*2;9B#9A4;&GBB6@@%H<9:=B#,+C<'3<7C!1B)$C:&D,:>:F
@r5901
AATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAATTGCGGCAAAGACAGCCGGCAAT
+
?.B$E#D%4;1G)3A0:@:?%8C/)>).7+,77%>*"?$D/()H&;64CA@81B/(=?:"@D'G(05C"*9A>:>A*!-G&(+<7/
@r5902
CGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCACAACACCTTGCCGATCAGCCAAACGTCTCTT
+
392".FE:+?C#2A'>0+93;6E(HE-$5C'!&09(2(!G3?75)H&$/$2/+B1=.2&<B=7>0$2E(@@;C-!
@r5903
TTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAACGTATGCAAATGNTTCATCCCGCGNGGCGTGAAGTG
+
@1%D'!1H-G>8A0*!/77?>&)0C(7,02#:4<>'$&.F7:@,'FDC)19;(*$"%!)A@F$C6.6=DBH-1#B1=>5+##1?/=0G&/"@5:@=":14$E<65$H069+>:E(.*3"&A8*D5>)?-
@r5904
CGNGTGATTACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACNGGCGTAACCCTTACGCCGGACCACCGTTCCGCCNACCAGACTCTGNATATCTTCCNCCATCCCGG
+
"&&$*$)*&+*)*""'#$'+###$'*++!*'''!$$$&'&()*"(*('*"$+)&%&('%*"+%+)$!!'$'%'**$(!&(+((&!+"($($%+!$*')&(++(%)$!(#%*(#($!"&"&'*!#&"%#%"(!&!!(
@r5905
GGAACCAAGATCGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGG
+
+&F3?"A%$A'#C&<"033::&(H)?/?&;6,"*36:H2&1E<-!9"-A
@r5906
GTCATCCGGTCAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACC
+
7+<=6-!8G5G$3'128G7F@431(E>GGDC,7F!=)#7>B&G23)&#??'6H;,3!BBHH1DA<9!#+#73HB>B
@r5907
NGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCACAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAG
+
1/GC6<,DF(#D,.#-5/?'<#%=D@E7#935D('GD+*E':3-7D?B583.&F:0+!19F)<9&<:,:2#/5$G&'A=H.,(-D:<*-G@-%BF1"A1)@E
@r5908
GCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGGCG
+
7794>&:*-96B>D#2=8*FBC15&#5'-?(F2@,$!F<A<.,>%+4!.F&:F'ACH*CAB%%+H:88-D<,7&4H"B@/>H-!B=89-#-:(!>?;#FE6@26)!=.="!*88G"*<>'6"3D3A7!@+$7.+G!%@;1-5>
@r5909
ATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTAATTTGTAATAAACTCAATGTCATTT
+
A?-7=A29D$B1H&EA.!1796'!-C0'CA3A%22/7(7DD&@")!@1!D-/:F+!<98;2)+))+()&996+4D(;9,7(F@#+A>'?)(HB'0@497')<G16HA+B/8B=CC"?)01E++1)8#.&<&D,(H3&8+*71-@)A8#E+(2*65H;?.9&,@G:D*:0&+23!E24!)3#B8/')+6#A25.D3A8B#B6$E6G/''$E)6C';#F4-,1*'G=18HC</4)0941B8E7(:,)0@F/5.?B5=5:)0$,2(E"+?ED4=GF+,)',E/.:)%.):49<&#>1%9?.<&G&@H=A#89E6:8"?<<;#GB*A"'5:.290A)<E<$80<')/0291)70(+%?&
@r5910
ATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCT
+
.-827H###3AA-H0:6-73C8'F!A'#-=#4<')A!A%D
@r5911
GGGNAGTCAGGNNTNGNTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGNCGCATTGCTTGCAAAAATTCTC
+
*$#*%'&&)"**"%*+%#$''!)&!*')#%!%+#&##()$*!+*)*"!#*)')&$+))%"#!%'&!%+%'&)$"%)$'(#$
@r5912
AGNGTANTNCCCTNTCCCNATCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTNTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCATGGATAGCGG
+
#%"#&#&'!'$(*!)"(%!&!*+#%(%"$*)!!"$&")$($$&#++'$%)&#'&(!)$&)%#)%%!+)&)%#%!+&"&&!%)%'#&&#+&*'$#+&%"+'#+(!%+('("$((#%*$'"!%('+)+"%!('+)&((*#*"+$)"$!%"!($!)%+!()!!
@r5913
GACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTT
+
3'&12?>0.519+5%".?B<A/;H5"'9AA.>A->;76EG@/3:G?-C?D(9A,(DD9DA"!HF&A67'1;?!<4*)=1A<)(AD
@r5914
AAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCC
+
;6$/5.#G,:"93)65F#%#1DG42=4F,-F/.G@$*#1"!(=&A'@7&+,5$
@r5915
CTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGANACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAANAGGTTTCNGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGC
+
#)'%+$+'&++"*"''*#$)"#!&('%"#*&*")"*(&&)'#*')%)#*"'%#)*****''&%+*&$)&&++$""!$#%)%!$&#)*$!*"!%!&)'%+'#)()&"$!('(&%*)%#%(**!+!%&)**!&")
@r5916
TGCAGCATGGGGGGCANCCATTGGGGCCGGTGGTATGACCGNCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGNTGGCACCGAAAGCCNGAACTCCCCGTATACAGACAACGGNTAACGGTAAGCAGAACACCTANT
+
0-$)->%#H0=()1<=H:C753(57"%@-(D>A:+H7823E7E%D%/"5>@!!0<)..1/))(:('%'17))@HE)56C!E.A?D(@G(GB!C+#572C>;5149-*$,$/)-5$?;=0'B(9-.1:=>$<:)'$2*%44!>@+&0<!E@6"(.8"#$
@r5917
CNGAATNATCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCA
+
'"!((""($(*$(+$(&%"%++)+''%(&%''!++'"(*)%%!(($"&&!'&)*&#$($'"")*&"*&$#()"&!++$)
@r5918
NGGCGCTGGGAAACACTGCCCTTTCAGCGAGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAG
+
"FF@:FB.90@&AG1F;<1.&;$6/%E/.6E8$8C&99+C#*6B9?;;?HB1?D9*'"=7,<'E8;8H(
@r5919
GGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTANACAGAGAGGTTCGNAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCATGCAATGCATG
+
@F*E>'F0%GG'>,+CCC:DC#FE0:B8..25*6';0+?H-4-#-))-)1:F0&4<>:;(9$#BA@+>>B=!=4//8A@A/=+?+/)4?*!7@A8315'8!144F4;-"9C$D:DC&HD?#<64<F3D5+
@r5920
AAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAAGATGGTAATAAAGCGATGA
+
3H$*B0FG5:H+-3FH!C7B)&18.*3=(@!F+(@-)2GG1@#07B'=H%@EE&24'<=F9(#$/@H4A',2C8+*>A$:2!&=C$0"
@r5921
GAANGCCTCNGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTNAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACC
+
!$$")&!"&)+!&#'&+*'&!++!*'**&)+*'$')+'$"*&)%##)*')(+!'&*($!*%&)%#+"&&"+"*#++%('$)"()'()!#&)+$)'!+$))+$##!''$"')&+$*'!#&*'"$*!#"$*
@r5922
TTTCCGGTGAGGTTATCCGTTCCCCTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCTTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCNGCTTACCGCCGTCGTCGCATCATCATGCAGAACATGNGTGACGAAGAGCTGGCCATTGCTCAGGTCGAA
+
)+)#&(("+!#&!(#%%&%&'#'"$#%+"%&$($(()'%'('&'$'($**!&#($)(%!!+"&(%&+!#**+)&!*&'!$'%')*"'$'%%%'+!'$!#"$*''%'+!&)$'!*))!(+++)))#%'&)!#'&&*&)+$#!+#%&')!#%&''%+#&$&()))($!#+%"'$"'#'((+($')")#)+&)+%'+$'!!!")&)&!"("%
@r5923
NCACGCTCCTTATATAAGCGANATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCTCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTNTGCCGCGAGA
+
'()$+!#&$*!&+!"%!$&"+&!*+&(#($*"""*+%(*''&$!(+&!''%'!(("""*$+(&'$%$'&$##(!#(&&&$&%('))!)*+)*&+%'*()#+'!""+*$+$+#$$(*"("*+!'*(+)#%(#!($$%%##+&!&##$&$'$#)$)("##)**++#*'#++%!!'"$("$$%"$%++'#!&&)$(#
@r5924
TGGTGNGCAACCAGCACAAAAGCGGAAATCTCGTTCCGNATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGNAGAAGGGAGGCCGCATGACGTTCTCAG
+
?506<<:4H"4;=C5%D8E?#2!;4+FG>B2<D"FED1(9"5=CD=7;=(::)G)"C''!F,HA%+#4%,5@:-,(@=@8B5&3185D-F0%-F;-?AH7;::<78:-1+=-3-G&E7+#5A/"G)((:HB"/#$A@!?1C!4+=BB>&*@$6A2>7E91=#GGCFAG(%7(>3!-;D9..&H8*!%"$6<A14$6%!HG!?'))(15#
@r5925
NAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGNCCCGTATTCAGTGT
+
+8=!'>B>A'7=9A%?67",/9+9D@(C@>G?F$6>6-;.'77%B()?(D$.D>@5E>2%@943;*FE86>8
@r5926
NGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGATACCTCTGCCGAAGTTGAGTATTT
+
%+&(%"'"!&'$))&'$$$%(*+$&&'&"#)(!$'+')+)(*($%!&!*)''+*()!!#+&(&$#(%#+#*)!'
@r5927
GTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGC
+
76';2!92%3/.D"9$0#)&B)<E3@-FB(:8/AB,"2F=(GE(
@r5928
NATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAG
+
#=*E@!AD.BB-A1"+*24FAAA>BED/9$,:%$9%'3C)E!9H+G4=:8*$:.1$F0.H%/7BH?12;F3B/",<'B5B&%<!&H*4/39=8#+39,FB04E1E5&@;H#4D#/E$H6D6154.@1/142B+:D=
@r5929
TCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATNGC
+
?%FC.#'H)'2E/1""20$>C)>7E86:3F-0#47&3%H"39<@;"=4E1D4=*75?3C49!H'&?5H&?9DF5;H."8!!6=*%$6GD!,-<&%C)524+#8<,;D>759(1.D2A(.*81-9E-"A&"(*B$,2D<0E):)->?*+3/8DG=-:H("6E)<>--:>5;-6
@r5930
CCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTG
+
8B/55!2</834(8/;'H;)A'B+?-:0;<4)4!H</C/)65B4798(*H+5A%;52,9!;&95B,,0-B37):9AEC/;B3/9(7)&92:9-'4-H5H;4%'6;.8)?>(4-
@r5931
TGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCAC
+
'$%>C?B*6@7",*#,58#CC8+2#CH1":)@(9B(B#/D%
@r5932
TTGCNTTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGTCATTTGTGCTGCCGGGAACGGCGTTTCGTGTNTCTGCCGGTGTCGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGNGAGGCGCTGTGGCTGATT
+
<&'724.$)'#<.A:H)/>388!46&9/5>$!,6H*67:/0/9:F547&$F&E@3C:A1FF:4+4126+'#88"#=*F*<F2FH22&%D?"FBD:+BD#A536@&*:=";*#!"(479+/F',912FH"B,'FC((H6G<E/(*-=%@4-7B>+7D2)&@B07,+-4-8C5-@'?@098?5,031-(E:60B?:(C%G?",B.CE>;0&A":1;A654@4EB&"=4&96A<H*-2#C0G0%0/>3C:H1"F;A3/4.B??+#)F=,96$EB5/D'A;*+
@r5933
ACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGNTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGG
+
++%%$&$')&#!!!"%++%%%#!(&&$$%*!)*#%'#+)&'+'$&(++)$'+'$(%)$&"&+!+++#&!!''"&)*(%&)("))%''*()
@r5934
AAGNACNAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGG
+
*'&&(("&)+%(&#!*$($!)*#*$+'*#*$+&'#(#$)("*')(%)#&%"*)"*%+%%#(&"(*('''!(
@r5935
ACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTAATATTGATACTGGCGGC
+
F3#B5C";=8#@-2">&77A524A$?.G689"06,%1H9F#$>&,D&":G>-/?
@r5936
ATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGG
+
63!@$<331+41E2=@D",(*-)9=,7B?:+&<,76C5,,@?$
@r5937
AGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTNTTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTG
+
E@<'7!)'/&6A:E.$35.)0<4-;%%7)00;>2*G@9?B9*6!.99<5*;E+;AD$>6A$F(>!=$>?&.B!.9@4).!H-<@0?*"18$:2C1:#3;91=92;HE'G'E5.&;'5EBG<"F%FC
@r5938
TTGGTGTATTTGCCNTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGG
+
$#2!<=2%='!+":E963=+D$3-#G)B&ADEFE9;-:G08C'8F4G61E&*'0H&#F<+2E78#=!E*6D&+C)!52:D=<8)<90?>)D9G".D/13)1*,F,
@r5939
TGAAGGTAAACTCATCACCCCCATNTCTGGCTATGCAGAAATCATCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATNCCGTCAGGAAA
+
81@B3637'&?,%H:'$!,F8!E5+A74+<8>)6B.B+-,+(+7!2+:C:;-83!4?(2H'3CG>4F<8:.9,?-GD>"!<@*:$()>,A%:F(0GE
@r5940
ATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCNTGGTGCAGA
+
:*5?6-G"6E@4>56-@60HE?'CE>G2./=:<?2&#::&C+$324!0F3F;121$@G45!)+46E3?$8+G,D;415!$D)%1%>9E+=31050/-FD
@r5941
TGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAANCAACAAGAAAACACTGGCAGATT
+
.!5.B4/%"5$B+H*1987,5=24?@C>81;1,$->+<9;!8#=(087'E3*.@/.4(3#&0(94
@r5942
GTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCC
+
5C;(B.F,G:@E)G($@736->A>!AD.$+,!:$61+;:#,8HB1$'3&F(*+('C36!=!20&($A6,&+03@H*"%4"9*D=)(C5.3;F<A,1E8'1';;#:>)B<:.C0)0H6GG%<@/F26+#;D8B1?.H$=3+</D5)#"41.$#?7#C(2=:F;?8<2719:%B-%5="=H/&?6$"6@(&1+C#:4H.$D0''7#(D22,.=,5+9;=3-:>.&>*$*(!F+09$HG:>(*$3!264+-A'A)C!C3?D
@r5943
TTTTCCCTGAGAGCTATCCCTTCACCANGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTATCGCCGATTGTTTCC
+
:DH,8/F"+(H3A808*'F.>*B'*F4?1/=AH*,+3;D#5())>@H')*C;F?)D9=*8-3;1+4+A15;,%33'0/+2"D!:G"C@/C>!?'%#"(
@r5944
GATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCNAAGAGATTCTTGGCGGAGAAACCATACTTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGATAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTCTGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTTACTCGGGCATAAGTCG
+
5#CC>C#3&D,:.31.H70H9-02D#<&C3@C@='G3EH;&16!AB5#@>,2(*)*G&=,99G>+>-,@>/AG&E9"?)&*;D5G3<3#/3#-=C9@+*+&0"F>*=F0&,213&"7BD<70FG?G7='9='?.0#2362FC,<'7+3/7,"=,+AE9)&BC,H1,4.G9)%32)3=4H2.*#/)7H"1@#;92&52FGDH,9-<:H0#:$@5C,$-7=+$A,AB$+GEE13=HG2$'FC='1;$0*878.*G>-#8?5!65>
@r5945
TTTATCTCACTGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCA
+
F/A2A)$A;0:%F>4./F+2-EG)$836'FACB75E9=G834H#2"($:)B*G$!
@r5946
GTATTGCTGGTTTCTCTCCCGTTCCTCCAGCAGTTCCAGCAC
+
H;#%'(C!/("#H%=B,;D?:9:03@046;>=+):F4+;?!*
@r5947
CTCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGNTCAGGTAAGCCACACGGNCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCTCTTCAGCATCCGGACGTTCGCCAACTTTCGCC
+
&!+&*"$&&#)$)#&$)*!!*%'"%")!'*)(!'*)$$&&($!)'%"#"!&*"&"(&&((!('%"*%!'!"'+(()'$!)"$)#&&*&%+'"+(#")##("+(#+'"*+'(%()*)+!"'('$)')#&%!+))!
@r5948
NTTTCGTCCCGTAATCAAACGACGACGTGGTTTTCGTCCCCAAATCCG
+
/&AHF$B.(GB2?62&75C4)B&<)+$)=&/394EC1@7>,>3/'=;G
@r5949
NATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGT
+
%B#.&9*6C-#5EG5(:B<>)FH(.5*,!01H>EE#7!E7E3:7
@r5950
TCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCNGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACC
+
:E'4'*BHH.G58'/>.H:EC*'559E2&BB@(6GH:G!B$:9E8$C#2E=6*(E/;&C$94=B"<;A6E$2/+@2CA%
@r5951
CCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCG
+
$)>BA=67/B%(>D79"*A/?D?.*'#EC/F0-B86D71)'<.:&1/@,D)8>>,0?.9==&H
@r5952
NACGATATNGTCTANGCANGCNTATANAGTATCGCCGAACGATTAGCTCTTCNGGCTTCTGAAGAAGCGTTTCNAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTTGCTCATAACAGACATTCACTACAGTTATNGCGGAACGGTATGCATGCTGGGTGTGGG
+
()&&(*#%%('((()*#'%*%"%*&'+)'%&$$&&'!&!%*!(&'*(%##!&&'($"#&!%&+##*'+&!*#*$))*+%++"$)!((%*"(*#'$'**)('#&+)!!#+%"%"($$*"++#")&$$+%)*'&*$(&$%#+**''+'+$(+#+'$+)+$)#"**!!'$*'!*"$#&++"*'**#+()#)!"$%"$%#!%*%$
@r5953
CACGCCGNAGGCGGTCGTGGCTTNACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCNTTAGCATCAGCTANCTCCTTCGTGTAGTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGTCNCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTT
+
+*AF*/G,#(D%@-+(%?;F?3H+3<<DA=!F%8@)$7+1@*+(=H>!&D@50.@D-5)3"D;"E-B?@7%'6"34;>B+EA#3@;H9#8B,#AE+354/.+(-:-1.F6>E/GCH;D!&#383<?E%G&DC=)1@%?C65>65G)0G.D9&9@A61$&&.7.,#E)3%$4&)0&0D"%=.FB%2?+>+37./($83B/4*E'$@3:"1E99=@3$AFF>=+9E5FD',6G,@
@r5954
GCTAAGTTGAGAATCGGTGATNCNGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATT
+
-:89E0DE!3<CD10);FGCF,;+@;$21G+88$45+1.?-@#6.';94B6@-572EC9/4(62C(/:,G*1#E#8)2,AF-1A-G5,*;/86>514#-1&>B%1$5(9-D"CE&=9=',G),;>&'B=
@r5955
CGCTGTCAGAGGCTTGTGTTTGAGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCA
+
0-FCC-?:(%<(,=A7,=@F/4/*35)5HAE("(7/*4?:C32G;*?/1A+<2;C2B+0B3
@r5956
GCATAAACACCCAGCAGCATTTTGGAATAACCGANACGGGCAGACTTCACCACATTCACCNCACGGATGTAGTCGCTGCCCAT
+
E<':<4@?"@C&26*23D045>.(?%")*9B/D,0AC9:@/2H,7=,""'.>(FC=4%9>"75$D5D8BC:B:D*'/&F'D$3
@r5957
CNCNCTGGCGTTCTCGCCCTCCGTNGCTGGCACCACGTCANTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGT
+
$#<02',:04D).<"=75A2-83<D.,B":+'7H>?<1?"7D-:+.E?>"&@%<8>>!BGB!B*-+D5)H.1E1/;;G@2=$<'3%F%75<$"+8++H8##0><448!-.0?3"$!#F.&,5%49AD
@r5958
ATNANTNACAGGTGNNTCGTTCANGNAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTNGATAGTAATATCATCTGAATCAAATANTCCTGATGTATCGATA
+
$)"&''!%$"#&((%%$$***$)#$$(&+"#+&$"!'+%#$'((+)&$#&+#$"%%%#*$('%&*$"%#+"%"*()%((#'!&((#$$"%!(%*+(+)#&(+$(#&("'$""+*#"&&!""$!*'((++'+'(&'*+!!+'!*!#*%("*&((!+))+!&!)%$()'%('"**")&#'%#($$"($)"$*')'(#'"&$$"!&!*%!!
@r5959
AGAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTNCAGATGTGAAAGGTCANACTGTCNGGTGGCTCAATCT
+
&&;)#;42*)020A#=E5E99>%-AF+G5F%A+.%64<!4EC1G+C/*5'=H11*6776(07;'0&@/%6/C-+H;E51@6:1D0?
@r5960
TNTCNNAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGNATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTC
+
%(#'"!+$(#$(+*$')"'"')*!'("$%$%'#()#"$*(&%'%#&$$+#!()&!"++#))+(+(($)!*""+*(%$%!*+*+$#*)')'&*
@r5961
CTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATNGCATGGGATCATTGGGTACTG
+
*)5-C8(1@G=BG":!EFG1'F*19>5!;$&892&!<?285@*G93=3&A8;E)2=63<@/D-F:%.:3/3-G
@r5962
AANCTANGAAAACGCATTAAGATGCAAAACGATAAGGTGCGATCA
+
&)!*$#$)#'*&+''*#()*)#&+$&"&*#&*%#)'"#'&!&(*%
@r5963
TTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACNGTGGCCCTTTTCAGCCTGGCCCTTT
+
F2)!+55(6"/C"#1BE'G@8E@&,<@!6=/8$6,$=H!*,F"9%C<")D:-G9<DC>:=)"4.&3D)"7<7+>!!'"&H-)
@r5964
ATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAACCCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAA
+
C:;75,AF3&E=#;BD<H*A&%D2"@4<60;7&F&&)(/8+F8@<6/4AH#)08?#0?4@AG!C#7(E$(3$E1BGG&?7.>D..$D=;7#"1110:6B>;
@r5965
GGAAGAGCAGGGGGCTGGAAATCCTTTCTGTNGACGCCGCC
+
A@<<!F)?+(&!;4=-)%%.:485*9HF8/E(H?CBE2.)5
@r5966
GCGGTCTGCGGGCCCGNCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACA
+
''#*#"%+$$!"))+'("$"(($"'''&$"*$$#!+%#'&&"&"')'!$"'"
@r5967
CAACGCGTTTACGGCTTGTTGCGCTNGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCNTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTNGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTNCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCG
+
"4@>#??)=-5=',-($"*"(67CE70>%?'F-7AG:7HE'34*FBB&++>;+>A30FAE%H"$)9F'G0H5":,/69"A.C=,A'.?BE""$<$9&69:85995)+BHB?3=>FH/5&BG#B<>@%B0A:@F&!A-"%3D"#":F++<C8(59:/6/A%*29$=(5!&;&H8+881E6+7;!0D&2(#907E5"&@39?%G72!F?2?'1G+.FF6,$?H5'!G*01BCH<#?1$D8>F##*;D!+7B.7;/CH5B471"?8D0A:E#$CC4&B=1E&:>D-B1GB"9'20G4=-"D9C"#B8+8.43?;H=*CD17!BC?B,'H*-+$"546@@;(H2H"/!7E0&399#FE74'1A*!)*2"C8D(.F99#9F8#2=&.5>("A>&)$@0:;&'D
@r5968
TCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAGGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGT
+
)H9G*G5<H.1*1!02&',9.+9(G81=F?B33(006*E3D$=?:>0+2EG!AH.356>@"/)%8@B;?"),!!"E),-G4%G"71:((+6$7!1*7>99&0'5'3(5@HG"'/"9E)D(-:!$G<,?%?>"'%)!8/&%!C90?>3;;
@r5969
AAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGANATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGA
+
3>5#3F;*?*7F3#9:7())4<!$";C1>5$/;&4G7)$F$+#74C4',36--6-.GB7GA8'?@B+;@$!.%72&;5*#=>F)8?8
@r5970
CTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGAT
+
A;/&'A'7CE*5C&(@06A=0G3!'F7<2F%1B*39>&1E6!"C"*++F?01G/'3@/2&%*&((6=&
@r5971
ATNTTTCANGCGTTCAGTCTTAAAAGCAATTGGCGGTGATNTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATC
+
3#4E;-'B09.G4A.39GD4EE=:175FHG:";";07AF.)/*%93'@1*;%-.';@!,#/'%1(803-E;)))!@/"&G@=G7.>=2C3%!0;,-<!B+F-3H+<&+>8=".=&3=&62FAF.(C(E*@810D*2H1&08%+;CA-;>C*-1CB27(.191(1;!<:9.4&-H*?:1,5
@r5972
GCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACT
+
G;)"0,E7>H8,/2;67/66G2$4/#A2G!G0:1',(H&:=5'6$@-F1&?&+.H!!?6E6(
@r5973
TGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATG
+
GDFADC?F#$=455G#FE;?9((12!704BB9/<A%%EF89A?&?=
@r5974
GATNTGCNNCTCTNNNNGGGNCNCAGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAG
+
&%$*"(%!')($!#$$"'(#%#"$!*##%%'**'+%++"))&)''!(#(('$'++&&#$"+)(+!(+)#+*%%#+"#(#&$%(!*%(%(&*%('##"'&$%"#+%"%'+&*!(%'"+)
@r5975
CCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAA
+
08.*B<+77-#%C8:$@+3A<?25)G5=GE#D<.E/G&<;E02264$H/!=/1A*>:'%F?8%'#+C"H3?&&1@
@r5976
TGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGNGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCNAA
+
414?'.#@B4C61E307)4;9!"$<61.->-/A>/@":#'5BA54G<=2E$C+4/@>%)AH)@9<D*D;*&73)!3&552H>B,=8"0($."*%'&&%.&'C(0684;HC'3,E6E?"8-(
@r5977
GAATCCAATGGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTC
+
)H0%%@/B?3.(>=&)-81-*)/#*HDHA,<>0H/4C"=@95953FEHC4%B=0422+&A"0$43HA7B7EE>-
@r5978
GGTTCCTGCATATGATGACAATGTCGNCCCAAGACCATCTC
+
0!(G-B)#>CH!&HE7"@/)"%5@D*,*8#A*3>48'=05)
@r5979
AGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTGAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTGTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATA
+
F&&6*!H5"8(=#9(%0BFG@*:!!C59/(G>@+)8'./2"E$3H',0$,B5:*5+*4"EGD#>F/HG5?:/)?B(0*+A#<B>9,/-!.>C*DD(4;"A<,&(24&2&"*"A6B-;4=%+H=,,.B3<*'2#7C,.;<;5$0=$37B>%<H?H6+-;9(%.&44?$717D>(%%34H?.
@r5980
GCATCAAAAANAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTC
+
*"!+!"*%)'!"*%*&+)'+++&##$++$(&%'%+&#++'#*+$"++"(&*"%&++!)!$"+(&(*"+##&+")*&%++'"#"!')*$%"###!*$""'()'#$+##%$&##)'&*&!"!%
@r5981
CAGTCAACCAGCAGGATGCGTGTAGGCNAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTG
+
72>5%=>0+E63+'G'"4488879<)6%D!:E%:5G?):F15BE69;@4#?3>#2259@@>%7?C?@<@=C;-72+#F$#F1+1.:
@r5982
AANCAANCGNCNGNCTNACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAG
+
$*''"$$!')&!)!'&$+$$&&()))$!!#('&+#&$#$'''%"*&)!#)!&&+#%!'$#()*)#&$#$*$$'(!$)*!%(*!*&$#(&)))&((*$'"+(+)*!*"!$
@r5983
CGAGAGAAAACAGGATGCCGGTCANACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAG
+
5/4>F)4H<1FHC*E0*$-#?C5B!#F!;25<A1*70743969572=@@5./>?*0./"A#>922A>5(EB.C#A3BC32!3*B<9)#D/=E1=)"@0'>349*:18A$
@r5984
AGTCATGCGTGATGCACTGGATGCACGTAAATCCNGTCTCTCAG
+
!G?"&3#6C9'5$&+A@3>4*@E-E(/&9/1B4:&0D@"E>,;"
@r5985
AATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTNAAACTGTCGCTTGGTCAGATCTGCGCCCGAANAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGA
+
465!/%>E>C9C$$!G:D1=%,@769,C80%%A65=(%>@($'GG;D?(8=(=1>2*&AEH>0G:2,2C8E@63H,D$09:"9A1+/(D4"2*9B<-9(&?#<?30A>034:&9.#15,94,>6*58,8FD9$>?#'7&3&.!:
@r5986
GAGTGCGAGGATTGTTATGTAATATTGGGTTTANTCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTG
+
>$;C&BHE%80BB*)2@3#$F(<H&8;>C3:A4C!93DF-EH+::>B6F)7*7AE$5".$E7D>H5+,9.8$G&9:3>8)"!!H#?C
@r5987
GGACCGACCGTCCGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGTTTCAGCGCCCTGAAGGACCGCNATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAGCGGCTGGGAGACGGCNACAGAGCTTGTTGAAGATAC
+
@@64>>A2-A8"(@D#=88(6C@.'($>02+5@@,DF@/!,9C)7"!3B(A82&!4'&CA)#)0?#)%A8H)AHB+58.*?8!F)/$0/,742/,E)+$!?$+/30;H@*2.8;,"01D(9@#AA+6=2/A1<A2EF=EG)(4)$<4-@@'*#&,-$9-)@/70>G$+@;9+G70C-
@r5988
AGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCNCCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTANACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGNTCTGCCACATTACGCTCC
+
!+&+(%%'"$)*(#!+(!+%#+(')$!&&&!)(#%+*!)+)(!*'$(%$"'+&#!$#)'"%((!%'#!*&)('$&*$%&&!$)*+!$$&*++$(%"%&#*""('(%&+!&("++&!'+**)&%!*%%'+(#%"**#!((+$&%$#+!)#(%"(!+#"'$&&!(%&)$"%+##("+"
@r5989
NAATCCCCGCATTTTATGCGTTTTCATGNTGCCTGCCCGCATTGCGGGGNGGAGCAGTATCTTAAATTTGGCGACANAGAGACGCCGTTTGGCCTCAAATGGACGC
+
!+&*!)&$(''(%'%+++"'#&%%"#)'&)*$#"+''%!$"+&)(&'#+*!#++!$"""&&#&&#%'*+)#+&"#)*#&%!(*%+*%$'%"+#"$&*#$#("+'*&
@r5990
GTCATCGTAACATGTTCTAGCGGGTTTGCTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTT
+
!@3.''88.>1<@6:>E*D$"4)79-1=F$*BD$/-%B"A?/7/8996$2#".51:CC6@>0@8!->@HB+")6+
@r5991
GTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCG
+
*+#)"()'%+'$#)("#+($!%+"+&)'+(!$(%")('%*#'%&%))++*&$*#!"!'#+'"#()+$)*(&($%!)%*($"%(!&(%'!(&#'&'*
@r5992
CTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGTGACTGTTCCGCTGCGTGAGTA
+
:)2;$9A5=B@AE7@FE8!6E=*,34E#EH:74C2-8>=53*+""2:?H/("6A(5GE8CA3?7:7A:;9B6"#=9$*
@r5993
GGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCNATCT
+
C34=*7<3$B;6*"1%:A&<G49=<F.FF@<7&%'F;52A2G?<'A$3</G%,(C*.,7)&E!)E1F".;+1)7B=C"23(@.&C'&%)?><38@,+19F%C-!7C:
@r5994
TCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACCTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATNAGCCAGAGTGTNGCGCGTTTCTCCTCTGCATCCGGC
+
G:+;)C,/D*10,.13)@9BB,"B.&@-FAG8#)H;$-'!F>9+?<8?3-!2$:?:FCF65H3=0A$1C#>+?>4HD$2>>&A%DA*2'+=HC93>)#9,&276%+2-B3FC$2:?F(3"!H?)>&;F>%,++B>=*>!C3572!14C3F%E*9A(-E+,6<487,,=?.&0<B8@$D&46/25F$:HE<*
@r5995
GNTATNNTNNANNTNNNGTNANNNNNNCCGNATCGCGCCTNNNGNCNCNACGCGNNGNNNAGNNGTGNNTTNNTCCNGNTN
+
$$"!$#"#"""!"#"#$!$!$##!#!""#!#"!$$$##"#"!""!$"$!#!$!$$!$$!""$!!#"$#!$##$!""!#"$"
@r5996
GCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCATCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCNGTCTGTGT
+
/?()<-H&84614A.>=>+@!%3(C;94B-A/68D=;#C@5B89"(!-,53E-5<8%-3F/5H+!21(:A).%*@.!>D,*:.>8E+.B3:@+@:@3*4;8?D%=2=060?==5F0C+10;4(2B9+/(*F0/D,!<8>4)9C?-9)'&$"0?5H6A.%)+'6#@(DFC:/:!))7F!6$<(G371F:<7*G*395#&-H87=?1E7?2+63C3@0+":/%8,6?6H0,>$!<'+HC*+G'**1*=C/.&742,;@5%96+9H$F::$?%;:3E090B?C'-.1"F+6!462-AD87@:B,52+!;)'@>$$6?AB(<2&A$@*:>/=,C.,()/>
@r5997
TTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATAT
+
)*+&)%"(+!')$)&"!#$&#&+!(+##''%(&#")&+"*)'!*#!'"%%((%)*$!#)'&((*''#"(()(''#
@r5998
CGNTGGTGGTGAACACGGTGNGCTCAGANAATCCGGATGAAGCCGGGCNTTACAGCATNGANGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATC
+
%*")$+**!!"#()&#++!&!%((#(*'!*$!!##$&!!*+%#)"#(!!&#*+*')!"')+*+*%)+''')+*'"(#*$$$"*!(+%$%++!$!!!!)#$#()('(&#%#"++#&'!!(&#)!#")"'%%(
@r5999
GGTANTGGCGCGCCCAGCTCTGAGCCTCANGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTG
+
=8:GD'D-%0#H&A%=,1(C0C#3D.5+:B%(*HD;2>E/B52(D4>)$,H>+AF@%@:)4=EE>/G84"3DB/!9.5$F
@r6000
CTGGGGAATGAGTTGCAATTATTGCTACNCCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGANGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTT
+
1*B31*>*"39D?1D.<F=D08'+&*/$F*EDF#C=E4H?G,9@%749-.">@B59B#?E9"H;'B+%DE(%(:F/G'?5C<!-.#+?HD!'4E4H*C04'06/5840%CG9!$&%E@&+#>DG'3:<8:CC
@r6001
GTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTTCTTTATAGAGCATAAGC
+
<493=9-/1!3D9D9D!(7*8)/A=*?F;H6-/<:G#$.)F:F',30'14D>75'
@r6002
TTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGAC
+
G&F-?&H017.=6?4@%%B)#>;2;@4H88(!/'9>@.G5G5"69,&<)8C17;=G69>9H/<#D
@r6003
GGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGNGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCC
+
G610&0?0<2";$D$=)779G1=<86G704!+=066)B8%.D?#2D'E+(#9(9#<8HF2E)F4@;*5CBB342?5DB<H2%<(
@r6004
TGCTTCCTGCCCAATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACG
+
;H)%=,%@#;@7%G"<,9?/-A-??73&+BD-;&<:*2E6@2-0DC6-93'5+-&=0$D4%2-"#7E)#'B%<$C64'-%A7=<#+.0*2.@AB)#AD5A4H@&&5G/8--7#*HA=8%8FHG21586B6BF9@,!E&8(<7/7#B0+D%'4'9B)93A$@'<6G<5
@r6005
NAACNAGAANNNAAANNANNCACGNGNNNATTNNGATTNNNCNNANCNCNNNCTNGANNCTCCNNCANNNTTNNTCNNNTNNCANNNATTNCNANTNCTAGNAAANNACTNCNNTNNNNGCGACGAGNCCNATG
+
#"""##$!"#""#!"!"#!$"#!"!$!"#"###"""$$!!!#"###"""$$!$$#"!"#$!"##!"#$"!!$#"!!#!!!!"$$!$!$"##!"$"$!"$$"$##"#"#$$"$!"#!"$$"##!!"$""!!#"$#
@r6006
TGNTNNGNTTTGGCCANTGATNANCGTGNCTNNACCTTTGATTTCTTTCACNATCCCGTNTTGTGAGTTGCTGATTCGCT
+
*)"*'!##(""&"%)'!!*&$!%%&$&"#&%#!!+*+''#(*#%('%"'%**&*"()'"$%"*(&+")%'(!!()!$+&)
@r6007
TACCTTCAACCTCAAGCCAGAATNCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCNTCTC
+
8=C3;G2.,">&5&0-/(G'1!!D=&---'B.-%27;H+2G+!$EH;+DB=2$@/<(.D$@5
@r6008
CATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGCTTAATTCCAGGCATTC
+
A:BD/>G0@"(%27&<=1<)B5B&#=:1*->/.D<G>3,=H"7*86:=2B0=8#->$:G;2:!>!-D47:)!G69B5<.';+#.(+?4EC4?*/4!%;G>+9)F/>!A":@-C8$
@r6009
NGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTANTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCT
+
-;:B1$!,>8'/04(&>D%4:CC@+!'<=1&3"A"$@*=:++=%?A#219+7;H9G1D,=02+D8.<H34'$:9A,%@'>9HA;7::;#>H;B-F0)H4,:H%2E0=?05$G0#BA-!-H<A'&72#<CDH6&=B8CFG42A.(F:C-4%20!CH:$,'@(/+A
@r6010
TGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCTATGGACAGAATCACCGATTCTCAACTTAGCGAGAT
+
'?$!F22?7E.E92/$(%9)8FA8*F768?&6),G37D%CC4-.$$,.EC@21:*,="39H7%.F%#-.C=BD#*3B=##&<4?;+8#$45-"->279B8'9?,FD@7>C-(F3H@8'4$;=587&(%*B:1F18G"=H81?,&*9;='&B1,
@r6011
GNTGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGA
+
%"C"67/2'1G=F52,0@D&"009#+79?>H>$<;E/9'/DG#15E,?261E.D5?A3<6*";
@r6012
GNCNGGTNCNCGTCTTATCCGANGGTCGGTCCTGCACGAACGTCAGCGTCTGCCNGTNCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGNCAGGTAC
+
%!"$%((+)''#&&$((!'%%"("(+&*)!+#)$"!#)*"($&(#+')()!"!&*#&+#*#'*%""*&(&#*$%$*(+%%(!+%()%+()$)#""+)*$+''+&!"$$+'#)($+#))*%+***#%#'!($")(
@r6013
NTTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCNGGGAAAANCCGTTACCCCATNGATGTGGTGAAAANCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGAGTGAACGTCTTCCGAAAGAGCTGGGCTATGNGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGAT
+
!;B%44"13!,=3B9!4+$,?.17(#/"BC&/76E'3/#%&51.36-:>EDD1+DB*F*-2B8=.2"GD8%:A2'B.(A$'&&CAH.2#!6&0!7?H3.-5#<,D8553:%9$(0C06H"B-D2><!1E!,H'D6?%(D3B)F(E(6?H6;>A&)*0C9=D.#+<A8=0C,2<'0C8)::&>BE*1"4*7'23@)$160<(!9)):F<1+5?$91EB<*++#6:-E#4H*&F'D"2)@=C;4&G,C.A-FE,)9C,.<2493(G4!?%D4;+91<D>DG#*'#<+<4$;-#2=%.B8.0;8#.10<4AD%4,E=((,A!/2*'?!7/%*8#2::29(,7)+8=D>1:.&#&'9A#%!-5=.4(D*5CC*?"
@r6014
CGAGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACNGACCGGCAGGCNGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATTATCCGCTGGCGCTGAATNANGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTNAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAA
+
0%B7>D/,)E21?.>2/5/3&>;A%GFA!G8#7'/HC(?B7<'8'9B012;8B*%$C<H,%*#A0.<31&B3(!2H8'D@:#>B2#!;'48E%2D)3"E*A"CCD$6:*H=E6F,/-$F+A8,4F,,,&;A&*GD*&'BH;(1'A+EGB:(1(.C+4,%#)5@C&.(08>@;84":A#<>')@&,,*.=+*%'B$.<4@FC#H&6.-59,!F1?C(5?G*$@B13A3D;G@&:5!9/(-834*#5
@r6015
GNAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCNGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGANAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGANATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTATG
+
*!*+%+%*()""*'+$!("!#&'#*'"$)%+#"'$$!+"%("*(+#&)%*)'$'!"'*#%#$#""%'%&$!$*'*'!!(+%!&*'"!#!"$!&))"&#*(!++')%*((*((&#&""#'((#%+'&!$$"*)(#)(!)#)"')$%)++%&*((!()$"+'!%###+%*+)$&#)&"(**(&&"&"&)#!!('&)"(%"+&"+&!%(%%**')##&*&(+"&(&%'#)('&%!%)'(*""+*#()$*
@r6016
AAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAAT
+
C2&H><#A,"13G34-8!*H13/&>8:;;2BG9;56.7.!-C:855
@r6017
AATCNTAAGTTTATCTTTCTGTTTCNGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTC
+
E(ECB3!F&.4A4E2F2;4%G:A2""!2G%&$3<;$EE;1C=.227:#(!FA1'-GC%)35B?B293"7<*!=>A"<1!58A@?$F
@r6018
ACTGGCAGACAACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTAT
+
E.-&7F(/8:6G&9!<1%'$"D-.<=06"+7%(6D<D(7:(E5=;C1G,G#;(
@r6019
GCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCA
+
E@B<-@054;++>/(#.D@&HD43/:2=F)H)6(.C#9,-406GDB!H1C
@r6020
GACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACANTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCAGCAGAACAACAACCCGCAACATCC
+
E'4=G-G;%C$')0+?7A9<<ACC;;;"EC%/.A/85H1EE43D!8%H@)5330F4F*HGAG$-=D6=,5,-87?##E;H@)?F:1<A<&00E(."6H?6C@)!3!&<1.9GC='&AF590(@2;<H('3>8,CC%%'C5)!!
@r6021
GAGGTGGTACNAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGT
+
038(AD$#8+<6+("5G6EC?)>;#?>40*("*!9A1898*=@:1<H01,?,'C8%1"D60GA=E.)"A;'8.A84FF34=!#
@r6022
NNNTTNCNCATANTNGCNNCANCTTTNNNCTGNGNNNAANNCNNAANNTAGCNGGTACANNAATCCNNNNGAN
+
$""$#!#$#!$#!"!!!###"#"##!$!"""$###$!$!!!#!!!"!!$$#$!"#$##$"$$!$!$#!"#"$!
@r6023
AAGCCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTG
+
'*66G-'=H/#$D4H+3/.A)3>,(/;!)-!))!=A5%1(@;;#!!
@r6024
GCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATG
+
90'80#=A5&)419H9>>043,8C52-20?AD@*51C5FAD?'2*$,/:.#/5*)/(3
@r6025
CAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGA
+
E.6!55+,%<'.*'5'<4!3%5E)%3"939=11D#<-<*3H=4
@r6026
ANGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTNTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGGACCACAGAACCGACGTCGGGGCTGACGGCGATGGCTCGCCAATTCC
+
#*@3'%B=,E#6)*(5F;D)C0.($?GC5&:11?#H-0F.40(.8G&8!!%$?#-4$43-H9;!AE8;)%/4B>4CA?7'$(>78.E61F&*A97'D4!-/H%ABC,/@;#B=50F*,$8+81$*(!9%</B"'66!0"
@r6027
GTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAA
+
'=*>/A,>2.$H.0="=%>?,?!#:'%6@,=A&>,"=%H!:BG$)8&&F?#H$5D*)'D?>?'+"=G2F.A>G2)C2,,*(7E9@78'G;A$
@r6028
CTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATA
+
48<E."E)%*:#8;"6H1#D*-/%'*97;<C?95.4?&/161&AB<>2@
@r6029
ATCGGTAATTCTTATTCCTTCGATACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTNACACACA
+
;"9<H0*',971H";1-4#8+@F!(407.*4.AD8D!3G6*?2#G#"E86&0%A11*584A@HE%();?'4(.85BCC4,&-3<E
@r6030
GAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGC
+
B$&2H6.!4!G>B7.+E%E:=>==(=)#*,B4,);3.;6D
@r6031
GGACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGTGAT
+
)#:-(456=,3&"!:6#7+(,B9"F9*)FH,?C.0C@G+2&=0-576FE.
@r6032
CGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGNAACCATA
+
8%)4"!A.(!B::>>8.1;0(:B0A=E8G,6#@"",)H;$#50CG(>:%D<8610E4$"+D
@r6033
GGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGCCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCGCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTNCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGT
+
H(0>C7D99:#5."39#2(/4).;@@.#5*?9"A>(#1>$0>6?.-%(+,17)608&/-&H??&E)"D0C;H>:,.(A-!'1H/02F4",:)"C2HB7AE3=C+F>,$AG#0D!-D!'"'D;H5D:>F+5A83"968<#B,7BA**#G8*6;$AE"#E!;&&8<D#E"G>+=!0A$@;DA4EHCHF350%(16&7<44#&F8'F%)&%/43+$,F*8,1"%9<'7$%F
@r6034
TGCTTTCAATCTGTTTGTGNTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGT
+
9*&>6C)*>A-&B""9*C5,;/()#E&/A+/E-@:H50A%74-A@*@,G.F)482H?B5E?;?C%C@4BA5$E1E)1?C#&2!D$&B+GF>4F>3A%HHA=2<B<0>/
@r6035
NCGTTNGTNACCGGNGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGNTGGTCCTTTCCGGCAATCAGGCGGGAATGACGGCAGATCGTATGCTGGTCCTGTCCA
+
#(%$(''"#$$)(+!!!)*(&"+#$'$'!&#)$*''*!'(&"!$&"%*+(*$$!%)%+&+%#*!!'++#!#*"!*"$+%$+&'!&#)$%'!'%*'&!%#+&"#!$)"&&!'#'#%'*+(*&)*)*(#!'%
@r6036
NNNGCGNCGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATNCTGAATGCAGCCATAGGNGC
+
!#!%'!'"+!&*(*'%*)%+&%%)&!"*'$+(*#+'!"'#+$#()*&)#%)))$)(#('&!)"#*%*!!&#$)+$&)$%$*$%(%"$&'+((+$+((%!&)%$')&"%!!'+!#)$%'*+!'"#"&$!!!*$
@r6037
ATCCACCTTATGGCTGCCNCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCG
+
&-@(CG(%'%/!'*(#'F<!1GHBC@D1>C>HE&C05(<*0(4C<'2%71E?$9BC28D9><:=#0>&@E7"2*!,)-4#"-/&D&0?:.F$C+-,'-0<6&+@,F'<%@1$GEBD%2:@>)50=8)(&8:1+8#&G!=G):4'1&A(%&90#A*)A'@#B&=,0CE;C%*F!)2&5F2*8??6(+5'6C<#%<'*9+3.GGE??>>"177A%#12FH<9
@r6038
TTATGACGAGCAAAGAAACCTTAACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGAT
+
4&;H!'#>="E8''AC-0.3FE-,'F:A"@34#$=1=G>2G(%2D,6H=B+=%%6:&6220BA4&?8-C@8&'8%'B1"8-5:5
@r6039
TTCCCGGCTGAGAGGGGTGGCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTNCAGCTCTGCCACACGGANCGCCAGTT
+
5(@F-)A+-%HC+28G390/?:AE$A+&:5=;:,1>33/%'CB74)H(187*3)296H)>!D77'F%=!(!D6.G<:'!B-!)')(
@r6040
TCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTNAACACGCAGTTTCCCTACTGTTAGCGGAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGTTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCA
+
D'!!#2&$44G9%);+5'<(61-74>@&1?,E&;,$A&B+D9%/4>";F&D=7);F.673H!,09*B(9,":4+?":!02;9G4-*1;+4=$&?A*FH%6C?>EG62*/!B22C!BH,1"-<(@'9=:$,AB##-B+8.>"-,$0-(#>=4%/68EB/1>C(E$3"66+?E6"%>@D0D1<+?"-#<(0+7G$B0<-*>B3*D(!,@&9/&8E94FF(C"H4:GG@
@r6041
GCGNATNNCCNTGNCAGTGCGAATGCGAACTCCGGGACGCTCAGTAATGTGA
+
"%"$&*!!'&!($#+!'%((("&#!"#'%+*)(%+*)*+)+*+&&'('$$++
@r6042
NNGATGNNANTGANNAGTGGAATGCCATNTGGGCTGTCGACCAAAGACGGCAAACATTATNTCGCGGGTATTGGCCTCAGCANGGAGGACACGAAGGAAGGCAAACTNAGCCAGTCTCTGGTTGCCNCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATNAACGANGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCNTTTCCCTGAC
+
!"'$%$!'(!!"*##+!)+))!#&"""+&*)*#%$)+#)+%(+%$!%++#')+)$&&%$'#&!&&)+"&)$$)&)'!&#'((($)*)#%#+"*+$*&"&&*#"*'+#!&*%&+!+$''(+&((*#'"$&!'&%)%*')!+'$*#"+#&(%'%'##))''#$)$'"&)&)*)*%*%"+%&$$("')+*('%!#+!&&!)&"#'!&$""%%"(#&"#%"++!)+""!'!%$''%*"(%%#(')($''&$%"+%"$!&$)+&*))$##+*+*&$$#$'"("&)%
@r6043
TTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCAGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGA
+
H16692(EH%!-=#D'>2-:,BE3F%>3*:H853!"5#/%+@7A7:%8GDDC?F.:71?>"4GA@:.$684B"%3%:EG?2G6B,(FH>8%>H:@-"1=!5-(&7E150,61332GA(5
@r6044
CCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTGGATCTGACCGAAGCGCAGC
+
:7(H/3.4</%F.&C+9CD&F!05H&'B@64>4:?<D'D/9!37#F'?#2(1/'E/0-/+>0C6
@r6045
GGCGGTGGCAAGGGTAATGANGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCT
+
!6$G>BH)B@EF4%E9(A=53(9H8*62684?*8$5%&"9(59F<H?F8(-HC'B<(33"830E?:<5?74'1(G(;D#$;-/8<GA4/$(5
@r6046
TGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAANAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATAT
+
(HE9!H6=%)(<+1=4DB<6=;:<$;H+%-@64A$A%$::#B#"75=6@1<E*1@2)G8G68/33,9!)D$5=?(87G7>@*A<G.A">)B)=+"B;FG4BCF@='6$=/:!D-+>G*%:EA,
@r6047
GTNAGTNNTGTCCCACTCCCTGCCTCTGTCATCACGATACTG
+
##()'*"&+#!)%()&(*#$("!%!$)'%*'%(!&%"&!$('
@r6048
GGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGATACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAG
+
FDF.*3"G+6A/-937'.-;2;=!$26&@78<,G2>9&&G/@$9=.@4.FA9*=81.G4)>,#;G%/80D$GE?(%#5?FC!7F*.71BA#6+3.%-%GD,9+E")2+C=
@r6049
AGCCCGGCATNTCGCGGGCGATATTTTCACAGCTATTTCAGNAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACAT
+
-?-59"(?C7@$@;+92G>F6$),%%,D?5(:G>,;B;'E1'#<6>?2:;<'#.7>(?'(1+A"(!7(**3<=F:;7GD36#"?*"!3%!+*@-A?'A$-C)ED$=<171H.6<G5?"C.59".!-1#@"+.@H$+/.>7D-;2G=6*721F$/>
@r6050
CTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCA
+
8CG%5%E(H)42=#G'D)?F;648@D!(!00@5E)$=,0:9E'(CF;8;G0)E?8$$A9E3522%44G*&;227-?"#.<(-@)1:9>D.+)C:%%"#@EB$1&>,3D6H.C*!,D7/F"26=>&<4<&9G$B'9*70#&0#,7ED1'%(>?;-<2/5
@r6051
NTGCGNTGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCNGGTTAAGGATGGAAGAGAGNATCTGTTCCACGAATCAGCGGTAAAGGTTAACTTAAATCGACCAGTAACAGGTGGCCTTT
+
!-;HEC7@H4-"6=C5&>23%:B2,%5FE$.2E++1-9#0);&$2,%#D3">;(1A7,%D6$)0G;"5/!B;>C62DB7?+4"F(B+1@"0=>BC:$%#5@!?!C,A)BGH&4?&-2D>E5;?FGD-:%01*&G?C'8(;,A/5!A0(&9@2<?!G0;!(B21F5:"166=2G833"69'$+7A6$
@r6052
CNCGTCAAATCTGGCCGCNTCCAGACTCAAATCAACAACCAGATCGCCTACCGGTTCAGCCNT
+
*%#E'@":##/)2!*6./$)%403:%<-+D0?%17E(:(DFF1A!>6:*,D%<G&+9F5(&/:
@r6053
NTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTCGTTCAGAATAAAACAATTC
+
&---@2=A=3?+5>"HAEHB?;D#(F3:+?8,+<'1(%38728=!;B>&3E1):G<C2DGF@--)C940=H4E3=/3+-?A9:"#!"('H;>B@70-G
@r6054
GATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGANACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGANGCCTGCCGTCGGAGACTAACNTCAGAAAAGAGAGCATATACATCAATTNA
+
&@3H1BC0@<$E3D!281/0#+#.>C;(G/<6,E>+B$:&&6C?*,#55C%G!*B8E;4**@<3>9<=DD2>%<1C'*1<A?>G1,HG@(=#(2C7+*""(!?H/%%9:.*"G$4C;C-D?4)2*$;/#?"'1.8#.).)#&)8?290%#(-189H$0C?@@8>+"@C0+;8.=-H))?AD#&BA292-G.B!++1B',&D<2$"H#;H"DF+B1:A>/?BA3>*7&=8GB*:@$*CC?1B8@(A,+9+8&8E.@@,,-6)87=))2EDA,,:8/7@>3)/(%3'>:3=2773<?;F)D>B4F?4%$<<;/;5-7/#EAF%+7#;/GA40AG2B@;
@r6055
GCCGCAGCTGCCGCANCTCATCAGTCNGGACAAACAGGGACGGGCTGG
+
7HDD%2#.E/"C11-3?9?D</B=02>F>(=;((>D$9'C76:D8F17
@r6056
GTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGG
+
(.?&>C"/0)!'F3H(6@5&D'-E,G$-D4EB&E=:9C6&()&2%(G'C@0.$4AE"!-!7;&C"H$)090"670%>2DC--4C+0'F0%379:*62&6#H*':B:GDD*&E+CAE7-G
@r6057
TTGTTTTATCCGCANACACCGCACGAANGCTCTTGTCGNTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGC
+
6E,+6<%74"(A,2,>G4F<$*,"!"!G=D&G$7E5C;=>688:C7<-68G%.#8!F0.??'3%8">@;1@!C4;:5D
@r6058
TCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGA
+
-E2&8>1=>D??%GHA./9*-'F.69:<>CH#'ED.(:F6D7!*1%":-"',@<C5+<,)D-4.&-?7"'8@=1<.59H<2.">'@9
@r6059
GCATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTT
+
&!8:5-;:BF%."*%#99@BF.,@G.F.<&D'1.(-8*EF5A2#=258,*DH;?;-*09"
@r6060
CTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGANCTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCT
+
3=B%5*;&7)"!"&38;,=-0=%B0?(<:38<2D5#<BH/#"9<"?*@""="+7;C1&:>"<@2&5C<D.GH5-&?0H60A64!ACBGB:7FB&,"*,6,'C+42E2A
@r6061
AAAAGAAAAATGAACTTGGCTTATCCCAGGANTCTGTCGCA
+
09697.B3G43F4(05'(C=('-$G'59CGB@**FH21"H%
@r6062
ACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTC
+
="CG,6)&6D&%,,&(<!5)E0G"E(62GE6B+;7EB;-GF".1@005!;22F/+&:?H;$H7)'0D
@r6063
CTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCC
+
64@;&C'D18$5H;EB$1F5&'&5-;7A),;:FG30/('.+?=02E#..2%29$D!H9A%G(!&.$/;*'=$*%H&?8A)GFC(B"6+H(6FBEE"H2
@r6064
AGNTCANNAATTCAGTCAACTCCCTGNAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAATCATAACCTTCTTAAAGCTATTCAGGATTTA
+
*&()#*$+)(&#&#"&%)&!()"""&#)'(&))#%+#((%!!*'"&*!+)%'#$)#)&&$%&&#&*(#%%((!+''"*%)*&'+($%'+"%#'*!*(##&*#&%!$)!&"'+%(!%$!+(%*!!+$'
@r6065
GNCCNCNATNATCTGANGGTCATTNAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACNGTCAGGAACGGGCGCNGNATAATGCTCTTTCCGC
+
*!('#!'''%$)($&!"!'''%!&#*'+**'*&&&&%%)"*#+%"!"(!&%#'!)&!'++*)'&)"&"*(#"$**"%"+!+%$*('''+**"!$+'#$$$"%((+!'$!&%$!()!"%*+$*$$%'$$(*&%#"!*%&!&"&+"!""*$'(
@r6066
CATAGTGATCAGCCTCTCTCTGAGGGTGAANTAATCCCGTTCAGCGGTGTC
+
3BF"%E7(11..5*CA%2AD#-DEF>67?@8#<-6E"1H6(F"6&?<**"#
@r6067
GTNNNNCNNTNNNTCGNNNGNTANANGNCNGNAANNCCANNNNCANGGAGNCGCTANNNNNCCGNNGNN
+
!##!$$"!!"!"#"!!!!"#"!$!""!#$"##"$"$""#!!"#"$!"""#$$$##!$"#!$"$$!!!!$
@r6068
TCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGNTGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGNAACGGGTATTGGC
+
=,G@G!3'4515:EGC5@'0D+46$2%H?F=262?.+:)*?@:9E>".)D'459=#.0A#D<<(,,:<:'06<5D35-);3;E9-!1%,7%)*31'7"0&<DE!%#;<CH('DFG+$*H*F<D1,HBA1"4?!:=*)9
@r6069
TANAAAATCTATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCNGCGATGCGCAGTTC
+
&"#(*#&($)$+)$)*)&%()$""#("$#'!$#!$"!$*%(!(##(+&'(!$&"&)$"%)$"&!)*##')$!(&"+!(*+$"#))%%$)"+*+*+!%(###'&'*'(%(()"*+$+*$%((!(&)(#$"+$+("(!'%(+"&
@r6070
NTCTANNNNCNTNNTNNNGTNNNNNTNTANNTGNCCNAGGNNGGTAGANCCAAANNNTNNTANGNNNNGCGCNNNACGACCCTAACNGANGNNGNCNNNTGNNNCNTNNACTANGTTNNGGNNNNTCNNNCANNNNCTNNTCNNGTNANTGAANNNCANNCNNACGGNTNTGNNGCGGTCNGNANNGGNCACGGATCTNNAGACNANANNNNNNCCNNNANCCGGNNACNNCAGTTTNNTNNTNNTN
+
!$"$$$#$#$!$!!$!!"#$!"##!#!#$"""!"$#$#"###$$##!$$#$$"#"!!#!#!$!#"##$!#"$#"!"#!!$$!"#$$#"$"!#$$#$#$$!$!#"$##!"$#$#!#$!#!#!!!#$$"#"!#$!!#!#"#!!##"#"$!!!$"$$!!#"$""$#$##"$$#$!##"#"###$!#""#"$!#!$!!"!$#"!$$""$$#$"#"$#$$!""!$!"$$#!$""!"$"#"$$$!$$#!##"!
@r6071
AGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTCTCGTTTTGCATCTTAATGCG
+
$(2#-18"6<%"A$&4B)=E0FH2E8';9F04'?@78:.$H6'!AC$;8'/C*?/.807.5@H
@r6072
TTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAA
+
&+'&+(('!*'+!(+"$)#)"+(*#%()'(**"'*%"+$$%$'!#$*''%)!&%$"*+*+"%$'+'!&"")#$!#*'!
@r6073
CGATACTGTATATGCATTAATAGACTATATCGTTGGTNTAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTNCAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTT
+
;=53,2!:;'6/1/A%-%?,B@;&1%??1$H59A711&702<,<6G1%:A(;.7?H.(@E+A7<AC8A:%$8CE$4&&6+3"D7!-7=@*0'0HGC)(/8:"8;A*6&1)/)3;:"@6%4*:H!BH'7(B((%F>(08D*16DE5#GE$!#
@r6074
TGTTCCATNACATCCTGAGGATGCTCTTCGATTCAAATTCTTCTT
+
F*)FB:B76A32@E&G&EH=&2&3)7,)2;=3H)77/28E>4A::
@r6075
CCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGT
+
"C")709'>0&,&/=:@:?=$C80"<(=+D8(8B-0:B4;?4>"?::$1(8>(ED!.&?#A&7#@F"G9F0+
@r6076
AAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAANCTGC
+
F1'7(*@7-3G%3$&D7C3(C-A02,:5*$903'032:39*#;/E&"(.0(2(A%25F)
@r6077
TTCTTATGAAACCATTCTAAAAAATNATAATGGTCAGAGAGGATTAGAAGGTCTAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCT
+
/+,:)-=.2C.!D44,-A-24="$%!,),4/.H=;56/3/A=#6$/0540.0-5&&E@?-1=>4@#?<*6-&'G.+52-<2"C.":E6&E!*$?+<C+(=2>*C60(7FH;).5:!-5:+F;0*B59A86+$?6/&8*G9@(=4<*>"8(=204&@9
@r6078
TGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTGGTAATACTTACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTNCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCA
+
F$>FG!':G=@(*)025!?D?982A*!(@0@3??8/)F8H!6#G/6-5,<A/'9*%*;B:%$';/<***=:0=&=,-H*(;8<8)GB+="(*;&(#$H.DDE7G)-E)H47&**79/0-*DD9$GC-G(#=E0371("53=7"H)E790D?)AEC#((*F,*81#5G!+8E@B8@>6488'!AC!5-H&7==FBE(G;/5:99(;>31+%-%=F(8<.E)ED-06==%>B-0--*@,9#&A5B>65*"'31=5%
@r6079
CGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTAC
+
2G/C>+=A0B7<!$>CG#:8+!+!D;F5=<3AE7=.',#EB20/>*002@5<%"6*&
@r6080
AATNNAANNTTAAGTCTTCTTTCCCANGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCAT
+
"&*!"&!&!+!$"%)#"#$+#%((+&$&(*"*$%)+$#(")'(')"'+!$&*+%&')*+$*!(&#)*#
@r6081
TCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTT
+
74>B<'#*?<3D;*#"81>G(,G742(*16EB9A(-2%<8-(H)-;"H4D@22%GBF1.958.H(?&203/G3!&:F#>BE1,G7>(2;64#G))48'A>G;:#CH
@r6082
AAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAG
+
*A.7+D8**$3>2@'@-(#8FACA#0H@,A)D<41%6<19+
@r6083
GGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGA
+
4/7#;@=$*/&>B*2$$?9@>$-E:).1/;9;=64:8BE/,'=2,%79"%45!459B0=E@E(#$+D$81?!>(+EB@%.H4.=010+
@r6084
ACNGCNTNNAGCNNCNNNCGGGCNGNNNTGNCNGGCTGANCCNTAATNGNNCCGTTANNTNGGNNAAACNCATNC
+
$#""#!$##!"$!!$##!$##$!!"!!"$$!$!$!"$!$"##!$$#!!!#!!$$#"$#$#$#!!#""!$!#$##"
@r6085
AATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAANGTCGTTTTTGCAAGCTTGG
+
67-/#?6H2)?.C1GG7@$<D?=C%6;%)=2'BB7@&3,-;,CA$.GC=)FC(*"*%/F=>E">.3)H>@87)845'="7,=.0-.,&#<*>BG:G-F4-/!/
@r6086
NTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACA
+
!('+%%(''!"*%&%'+('**+)#+%)%%$!%$)$!"&%)
@r6087
CATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGT
+
!?D("1.:(!0+82>'!A#>B7:'>7$!+9G6&3C>F22=:%+.<9GB9@7B</80:C)7C9::8:9=:",(!
@r6088
CNTCAGTAACGTCAGCCTNCGAAGCAGTGGCTGAAACAGTTGTTG
+
5@)!7E,C4*7!A=B3C.1<13'28*BA#2<H/A!,3;G$E;@:$
@r6089
TATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGG
+
"+%"+!#$$&*#!")(!*&!*!#!&'!"!#'%$#)#+#'*&)*)$+$'
@r6090
AACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAG
+
$)G0+H4*D*2"/;?#;0#7F7:>52@-*/?-8H!"8DB!@<7/,6%1(
@r6091
NNCACAATAAAGCCCACCNGTTCCGGCGGGCTGTCATAACACTNTGTTACCNGGCTAATCAGAATTTATAACCGACC
+
"!+%&#)*&)+($$'!#$#*#"!('+&)$)#"&+%+$'((!"$&*"+'"!"#)&+*+%#'")&#!!(!&%(+%+''&
@r6092
GAAGCGGAGAACATCAANGACTGCTACGACCACTGGATGAT
+
8<=2-41#$6*0@CGC7%B8#%3#5F1-2E9@F>H9!+-44
@r6093
ATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATANGCACGGGTATCGCCTTCNTTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCC
+
:+633(D?D=DD#$<(/)!/<D,2>F?'<*1.0,.#@;;,2&)!#=C=)-7&.09BD?$;@&<0=5$".F$.9,4A%.91!HFBC->-B#E:6&6'C0G7"(84H;C;>C+9EA90=&>)#">DC'(,78@!&4;'+2"
@r6094
AAACGAAACTGAAACAAGCGATNGAAAATATCCCTTTGGGATTCTTGNCTAGATAAGTCTATTATTTTCAGAGAAAAANTATTCA
+
;;1)$%3$99#1++,1)/,G$3B3''G%29'21C&6:F<;9E<E#%2F0!1=%C.$90"8D7,>EH&-=%(G4!>/0F&.GD!1@
@r6095
AGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCAC
+
$+EACE*.A'H/7E-C@*!1C4@.74@,1DD-AB@(F?:=BF;(?B+?E3$BE89-F+$#&$
@r6096
TNGNATGAGTATAGAAATGGGTCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATG
+
%**'.*84/*+;%EA"5!'&D;,D2?#7%H&':1D%5>"%AA3/3%7B640F/G>'F$&6;'AFB03<3EA99,4-5$8&)9
@r6097
NGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGNCCGGGCCGTGCTGANCAGCCGCTCACTGCCGTCGTCCGCTGTTNCGGNCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGN
+
%%+"%!"+%)&(!'+&%+""'''()!+'(&"+$""+)*!"+("(+!"*!!&'!)")'#!"(+("$#'#"''%'*$+"$!$($(!+%#"'%('!&***&*%()"+(%+"(!"!%"&&"%'$%+$()')+"%$)%#+&%+(("'')$"")
@r6098
CACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAA
+
91>7C.*H;?4G053D?3EAA68-*/C,(20CC678#>+?%!1B
@r6099
CNGACGGAATGTTNAGTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGNTTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTNCCCAATG
+
/!*%)4??;2;B2G<48??F:'7>'F<F7+,F2'<G9+=8G+.$6+#=1;0G0=<C(F6B.8>*ED,%E:,,G#6*2?")-?;GA2-CH#>=61561)('9>*$1'6D09((H9F(:@GA"5)*9G9H=D8!%E:86,>.0,2"H#,D"')92-'
@r6100
CATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTNCGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAAC
+
H&/:!"B6HGB+$)!B$F,45FE;1*>8>"H6@3C22G-(0A3><4&6657/BE1.>=?@EC(4@F;#::<1:>9F#>HE/6.CE4&")>@1,>)80;+=BDH*21D6,D&%;@6*;<58$)8@5=>&DE2F?@="E0F@F:%1#;*+<8F<8?=9"0A"*+&-6F)
@r6101
ATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAAAGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGNAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCC
+
,'<.F?'C"38..!?E19@43A=?09-6/1/3*/:'A7#00>/.H+:3DBA5=23+)4C=76=$5'':GC,4%")5H!,<>78@F1;C=@0&C!$G%;;'!H9/"BC7C:869'93&BABG*&3:;%?&#&,&HC:
@r6102
NAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCG
+
"9-69E%)CH8G378$@/1<A5#--+64<F;-04$5:,#.
@r6103
TACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCG
+
>=8,*11C''>&>:8?;D<3%1=>.8A8$>#/G8+%&G%9HC4CEG#*::9=:0'/G"47/6-5"*D-/8,:,3,(&/-8?#1207(7;91)#.3-62+@0#)&<%184GG&."5'*1-C0-&)B075,(D<D
@r6104
GNGTGTGAGCACTGCTNCGCAGAACTGATGAGCGATCCGAATAGCTCGATNCACGAGGAAGAAGATGATGGCTTAACCAGCGCGAAGACG
+
*#*+!%$"+!+"*&'$#)'#)$*%"*+&"$(&&!$()#&'"*($)"'$'+#*#(&*()(%!!&+*''*(*!$!+$$+*"+("'")*%&)'
@r6105
NAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCC
+
"&@:-)(C2<&B)"D:<A(96E(F48E)1"%-'8+6@@02"H@"-9H@$)H.AD"=41)0>$!'?:E
@r6106
GTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCC
+
319DB*C%-?GDFD(B<7@F/F-:*9#,-7;2A%1,2+D'3.')D-B7*F<9AE>HC/H09&?%00=(.#(CEA=C<?:"&0G!*F&
@r6107
CCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCNGTCTGCTGGCCTTATCCTCCGTCAGCTCGACTTTTTCCAGCA
+
"('#*+'(((&#&"*)')#+'*!%%'(""%%+$!)&)%**!(&&&(#()((&$*##(!)*#*$%(&$!$(!#""!'+$'"#*&)"#")*#"
@r6108
GTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACG
+
3G%9-8!*.FH)<&&1:39:#&=@B737;E1#8A<>D#FF7098A!019+F3(09G+.3!0B@1%17*!587#F)?6$);,($)//E6"*"2+E$3830-39(-H-2CC#$GCG*?&)9/=A;5).9"5!)$+#AD'"='B?D%&F2+EC(/.B1:@79BE"'BCG&>:+/(8(B"3E.<$E;/2>5!C*%"=-$#H':?:&)$20;=29"%$(8.A"5?B')H&>)"4
@r6109
GGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTNA
+
0G3$0C(&*;8*23;@9$B/2'="@%.B28D3)&$92H;?"7B232+@(331<("74.<CF#
@r6110
CACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCA
+
/?6"#G11":7C7E$>746$G*10DA+B94C=''&!9:9--<G:=;+(7!9:'&/(H28#';51
@r6111
GATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGC
+
3935B;A45!)D9$--G99'+>2$D6(AF;<"GC*HG0*&>>177,!D?;B2=H-.&0--@H6;>()=@7338
@r6112
TCAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAANCAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGCTGAAGGGATAGCTCNCACGGAAATAGAGACTCAGAAACAGCGGATCAAACTTAAATTTCT
+
5CC;:0#=FE3'1$G)/,%%04&=+;@#2FA!/EG+*4E.%>E?!)?@%G1B&BH@)"6B68:FGF0:A7'#2C&/G3:.+0<;C3@HGD!D"/E+-?5B&,'/!/H!2<,-7?D3C):%#=;1-,HD1;)C3)(26:+6<=,!.C<)!37:@"75#,)#2,-8BB6=.H;6A'G,A
@r6113
AACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCC
+
GG#'>%;1.+(=/*=+A*"23!4=$@(%A5+/%5."$CE9D<G468(,
@r6114
CGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGANGATTTACGGGAACCGGCGGCAAATATGAGCCAG
+
B$ADD51/3(,>$7*@,'0,A<1F6G>27G"F83D/,5H"C#9=3C-7DF)?>@=378-DB>1%<'CA>9*(EB=;+.C16@+
@r6115
GTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCANCGGCACTGGTGGCCGCCGNGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTNCG
+
4.&;@FB%;3#='.(!F=?<?0'%G%/GA2-C$2*%:-AD=D!&>%,F3+7#>B$D4EF&:9'>$"+5/F",94%1,&E,)3<%;DE%+<&<H*EF&6A4D#%FF1E2.<*6+:D+*-?#'9)#&"%(+AF
@r6116
AGNGCNGAACCNNTCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGANTATCCGTGAGANCGACGACGGCACGTATGCCATCACCG
+
%**##%'&&$)!!#$%+"')")&#&(&*"(&)'!)#)*"*$*!#$&)&$&%$**'$%$!)&')**"'%(#++'+$$(()$#&"#()
@r6117
TTCTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGNANCGATGTAGCCGA
+
(*$')'"+*)$*")'!*&(#!*(%!+('+(%&#%+&(&)$('%%$'%)$$++)%
@r6118
CACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGGCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGANAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGA
+
AB;&AB5-'CF.+!93?E408+F1/G55A-%/(G<EG->!1/)@!,49>G;2!&D=&H*&@?5*!,?0E3(900$"AC$%71+@5&-08C33<?B'70,7513,856)7AF7)>>=9B*'(>C&;6%)
@r6119
GTNAGACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATNGG
+
(!()$'+65D;:)0+F:;C!4!H,'09F8)11(*B'C=&3AH*5*3=5C'E&(:,+A@*E!((>H0C;+8*$-5@)'.!+>1(F#&37%<'F7.H&)(1-BF+#1.3=+FCD'5-*D3E7A)*#<:$03"D<'<B,--4$-1@?(';EA57>"@
@r6120
GCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGT
+
F@3<@*4"%#%.6F@>G&4.5;DC,*.9(6%9":4=/5$GA4*&4'<$79/@+B)FBC:FFH1998$'*9&'!0<:;9.F&&F
@r6121
GGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCANGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCAT
+
AC2<#:;,D:8%$%-8.-.413A;9:@>7,1G??)4,+;5,1=FC*:!B8>*"+8C<99:@991<+E:G@>7C=<>>4D:
@r6122
GCAGTAGAAATAAANAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTT
+
&*)$(&***(&+)#*)$*)#(*)"'(&$(#($$#+++%"("&('")(#(+&!*$*)"*"(%'*$#+"(($*+''#
@r6123
ACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAG
+
(+*$($%%$""&'*)"$*&+&)*+%*'*+*%&%*"""#+$'(+"%&"+!+&$"''"%"#(&')"*)(*!+&)&!+)+&+"'+!"+(&!(""($$'%*''($
@r6124
AGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCNTCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATNCTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAAC
+
=.C8*9$%#.:09!3+/=$=*2E;!'DA%,@8;!2%B74,':H!95H//.";<<@!3;D/;;&'BA<#.?'7=H@3H!B0C@4:#D/H=3<8%070',?*$*,2,+),F$%$D28&B*D0!GE?E">3,,GG=FH*9B3><%:>1$2!1<B''D6<)8@&'2+8B$;#62=;,4BD2&7*%G6.$5>38GD1!-;E&C/$G$@//FF+5;7-A7B;FD5C2&DC/+=/!&81781/%384A*)'3??<C.23*$/B2?:$;6(!,&@+.*E#6D-;&:+E$5
@r6125
TTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGCAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATNGCGATTCGCCTGTCTCTGCCTANTCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACAGGTCGATTTAAGTCAACCTTTACNGCTGATTCGTGGAACAGATACTCTCT
+
++&'"+(**&++&'#+%)%!"&*+$+%&"%!!+&!&&"#'++)'*!%""*#&!)$'*($+"$)+"&&'!"$&%+#"'"(+*()&$+$'*!!+##!#""!*)$())!*)!")+!+'%$$$)')!+$"**"!(**%$)!%)+!#+**(#)#""(#!'$#"%*!#+)#+)!*)!*&)"!#"(+#""'')*#(#"%&%!()#%##&$'(*$"*"'"#!"!'%$+)*(&#'*%'#+(+!"!#$#$&+%%+"(*!(%'#"!$)#!#"('#'($'!*#"$$*((()#+"&&
@r6126
AGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGGGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCA
+
+.CF4$;#A5B:4+%-/"85HH*9>E"&)7:+&3$@1.0C7",>=*&:B!>1=*1>G=;6#=C"1"1H87?G+54HE;)A7:.:'+(E!!H;-3,DF9>4B=%"2HH$H8.>*,H+:4#26?19#!)*D,C<0,'>:5>?H"H*#558&>C$B<7*&2,)D)/C!>9&*+%<'"/C>37.%9F,,B'</<9BG<+?06$26F@G28"0A(.#9<=!/5H41
@r6127
AATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCG
+
>E7:&G#H.;.&58.3;A;62C/*7<))'8C'2201D!@3>=(%94
@r6128
AGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTNTGCAAATGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTANGCAGCT
+
:/'*GGD/G).##&26F)GA71"0:<+-6B-%>36,%-/#8,>GBD1-%.$&#D%$44<H!6B.&&>+G3FF=;)19'*4*CD*#-?;1HH<77(C=,>,&</5<D390/H(=5%
@r6129
CTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCA
+
=/91E*AHCA6CFB,)G.;GE15=F>B6?+(7)/?(%*E3
@r6130
TGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTNCCTGACGACTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTT
+
23C7->!1?+6H<9-"B+(@52673E*:@!3B2CDB;-C%.)@&(%"!8.7@'6/(24/#7@B'6!B5*F5?%/&F;8">7B-24"'-*7C'(F+ECG=<;%E0DD'%.6;E9@G;>2:.(=,5272/9-F04&B!0#G
@r6131
NTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGA
+
&9/73&0.=,?>%0%$!7,7046BE*&-(8;38?22(0-+<8.
@r6132
GCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATNGGTGATTCTG
+
&7),!!,9<=52B9!:/3H"0'96=.+=:'<B+-);E/G4>*/#0'@)"#?&H1;
@r6133
NTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGCAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGA
+
#@CG32+D<G-;@20"A4)+-&58"?>,".-?B>4@,;@C987==A661(6,!,*=4?H5,6."&>!5?44(?B:A>H&2%7==/!,GH@!A?!3:;
@r6134
GTCCATGATGACAGAAATTCTGCTTAAGCAGGCAANGGTGGGGATTG
+
6!-1,;6='D!?3"%>F"F!E*!2459(07$D"=C5>5&#&72,F$&
@r6135
ATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCCGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTGTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGNCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGNGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAAT
+
=03+H?B+CDGA#+>(8=BH943:70)@F$8185@9#=/%#66@.+)39?FE"A,6$4B=."'D*@4<;:%"@:?%;0;-0(?$8"HBFEH&A3#?0.#';?:5("B!H8;.@'"F1&G!0"<4>(6F7HD=.1G8(<?%D?(=@9?.!+3?B&/F02%.FHGC%,2G73>C6"-F)%9=F+/'G2(;64=H4E+*(*3D1HD,E(=""1,,%,;7,)<:D589',*,GH)??9;75:-$!@,A90>D*.;9>1HH0/@<F4"96+6E2>G(:D*(C%H=C(#><!9H5>,B9*F3A@!544HF=9=
@r6136
GCCACCATACTGGTGATCAAATCTGAAAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCA
+
;=7CH&:7C$!6%3.$D%%@&B=2'EED1@,(+"<%,<7B9E)(+<"*DH#,8>A.4&2?.A!G&>HG:F?*A-&:..:6%2&)5/664?;-0!4&&
@r6137
CAAGATTACTATGNAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTT
+
!)'$+")"'(#(%''$**%()*(+"$(')"'+%!'"$++$)$$*#"$"#(#'&(&**#&$$!!$+"&"*(!%)&!&*%&+%#+'$*
@r6138
ANTTANTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAAACCA
+
#*8.>28+H*5,++(5()?A==503*<2&=<*:)C',>!'.$">.?'72
@r6139
GGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGNAGCGTTTATGCGGAAGAGGTNAAGCCC
+
;2/'<<3-6)F(C?2/(?*E#<7-9%):&562D4:7B.*,%9$0"C;,(4:/:&?&="AC'E.-&;77'"B0G6.!1,%&E2*2G-A@'BH*,"(0-F6?&&
@r6140
GATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCNAGGCTNACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGG
+
6.12D"(>,45H(0+AD77#7(*!F)+=<4$E(<HE4%%$C."92>?<02'G5B'=$H3F9;&'D0<4;-.G(:C@++<>?1)43
@r6141
CAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCNCGATGGCGGTGCC
+
AED$+CFB3E5A.$58D,C01F*.)"$GBA721,.$')+?9#87AH6D(=<C-'G>"AAA.H430!#-36%C0('EF;<:18%CGD-/4)?&!H'
@r6142
NNCATTTATNGGTNGTGNANNAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTANGTAGTGATGA
+
&"(()*)&%$$&(!'%'$"""(+!'))!$&)()#&($)"*((*%+$!#+!*&#%%'*!)"#('**&%"!&$("+$)+"
@r6143
TTCACCATGATTNAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATCAGTTCGTGTCCGTACAACTGGTG
+
3?E8>!2@:0H#CE,(!+"-3%./56H3H?C(D6:3!H4"#-&1EG*62:2$76#.&;77B+:0!.=/<F#H
@r6144
TTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATAGCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTC
+
1F!6:"93A4E%!8$"1'-1D-C-A5/D&)/A*5?79,+27?4!BB-*4!;$9+%DE;.)+3!&<,@E</3=>:814=%!*@A6G=C<A:'C3C!G.GC9&D.."76",+=HE/,A45F469)"9;)=2C+#!$7-C-5&=7<@'6,@CF#*C@#-0
@r6145
TTTCATGTTCNTCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCG
+
H-!+(3791>*E2+48(8)/>)DA#E;B64D-!:-B@/*<!8B13>EA"!1H9%/>&B<#D)2=9E@C8!'C-CC:4+#>4@?%*/A:&&@)<
@r6146
ANNTTGTTACGCAACCAATACTATTANGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGNAGGTCAGACCAGATTNAAACGATAAAAACGA
+
&#$+&!&((&"'(#&&+#("$"+(!)$*#%%'"*+&#)(+**"$"!)&&$+&#+(#($!$)#%!''+!#%)$$'()%$%!)'"%''+&"%#!+)+(!++))$"($!
@r6147
NATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAG
+
$.."B+#@3*$$H:%5=GB(!,('<H9&$DC>@;-5;+#':/B(H3'E!D313**!H@=3)(7@9:,7GHD-)4,2G6E56-,6A$G>C#A@>7E
@r6148
CGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAG
+
--=<2)6)$>;?;4E!<9,,!'17>7$#;4>AB@(17*:#G314!0%-@%
@r6149
CGCCGGGCCCGCAGNCAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTG
+
&%,B6@"?E6=)*5,AE<B4>;&G461F*#A?+>8C.'022,00D21CH*@!=
@r6150
TGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCNG
+
C:&E4(,+&?"#,#D)#GAEA/'D&$.A"</??,@#D39)"2753,.6:B(F%"C-'>B=36B/4$8:1@,((@3
@r6151
CNNCNCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGNATTATGTAGTCTG
+
"'%""++('&&'"%*+&$)%#"%*(#%$$(&(""$##!)+!%()(#')*('#%)!*)!(*(*'''%'&)+$$'!+!%&#%!)"#''#'+!+#')&)
@r6152
CNTNNTGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCG
+
%!&!'#+%(&%"+!"!*)%'')*#**)""&(##'"%#+""$%'###++'!!#!&'"*#)*#'%'
@r6153
TATGATCCTGATGTAGCTGGAAGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGC
+
((+)&("%*'''*)%+$!**#)(!)!(&'$!)$&&(#)$*('$(#!*#**%#+!+"'*((%"#'%**$+$
@r6154
NNNNGTTTNCCGCAGAACACTGCGCCGGTATCGATATACATNTGGTTGGCAAA
+
##$$'!$&&+!)(+$$+*#*#+(%$"(&('("$)'$+''+'!')#%"&'")+(
@r6155
GAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGNGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGNAGGATACGTTTCACTATGAGAGCCTG
+
68?>!;BD1#(37DBC7.#D?A90+6)6$=?0<C?4%5)87A(B4,3&!2;@7FF/?DE&:1CGH$8#1A#G2!!"A1/1,8,<2051/2=.H354?1#-:D;1079?FD7=AD&+8E>'GG#G+*#("@?5,81$>4!&@60HD=<)D9)%0#*86:?=/$5H947FB"-2A6/A9F!-35);93DG1<(F/-.8')?8G),4DGG;A5G'B9HF6$B9&?5!5F5E
@r6156
GATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGTCTGGATTGGTGAAATTNCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTACC
+
()3:&8G+.&7A+3!-?9?<%!DA-0$F<=&;#!?>3/;%B#&4E,3#38?#>=37,C<*2"'B37)23!A72AD2;7F*-G<>A:@@G=,)**?D'7.76AE,!>E4&,%=!H8DBB"BCB=E96%*.1D#".)?B;<CF5HH'6;3;',:1B<?:2"8A8+$H-?1?2FH-@><A")>$+(),4;*6A5A3+D*.8(E&>)&&GAF+@"6-<9=0@@201&)!-$F%DCA<29%&>"D3!9")
@r6157
CTTAAGATTCGAAAACTCGCCTTAAAGCACCGCAGTTACT
+
-:A%2G?0#8&!,C7C1E?3%#A@8)*G?2/?@<6?&@*+
@r6158
TCGGGCGGNGATACCGGTGTGAGTCATCTGAAAGGGNTNAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTG
+
$9-2EEH&-1C:"6E==/!6C$'/11G;3.;8%37G#94A%'3H*+4;AD77/C82%98,>(/4%)B9"6!.4.'
@r6159
CGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCC
+
$HH)!%&"-!7=-">.-<-E(.?*1GD+;-CE87+)D<!-5C;;'?F
@r6160
GATTCCNCGATAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAG
+
#$%#"%%&)#!++*($%$+!%#!#$+%&))()%!&%&"*$())*"$"
@r6161
CGGCAGCAGTAGCACCAAAGGAAACCATCACCCATNATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAG
+
6((7)5(">7D<932.E/-,.#7)F#2G?DA(,C(B#:2B(4#G(E.;--CBBG,,H"59.3,#4-=>3*#G4;A%C+8"5>/83,@EFEA0#9.H&+@:E0EF&H+4H:?%D&G=HFGH!7*!/":?
@r6162
CCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACCTGGCTGACGCCGCCTTGCCCTCGT
+
:><.>E:<$%(=""6?A6$4!1!:+8;0((,3(%9A&!(97;!@@746AA/<59/9<@&9-)$<9HC5B'5#!--C)G>)6.?332?;46F8+0,#'8%8:>;5(6AF4F2?8%F=7?8G@9H+:/01?>GA.;.!".=3CF1$:3+H7*?.";)@6A5,@":=H47,<8G%FC=33;C&/F:)D/,>%="B)-?)AD('+B<">>4;5',HC
@r6163
GTCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCA
+
+F*';DH/7F8771,1C%1E;5%1<3>.0C8C5.<?0;<+1C8B01<0-996</6#5(4;
@r6164
TAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTT
+
G9G'2+?;B9)&(32#G?908?5'=C+4=-C(7-,C%$H#B>+*7*+1?;9;-EA*#+2F377F?7DEF5>-=6@*)>?,
@r6165
GNNTNAGGNATGGGTATAGGNCGCNGTTNGNGACATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGT
+
*""$$#&(!&)'&)&#!"$&%"(("*)#!(!)%'%$))%&%)+)"$")(*!)"%)"%)!)!"($)+!%(!(+$$&*+)&!(+("!##'%(+*!"+##$)!!("***)!)+%"))**#)*#&#)'"
@r6166
GCCNNAGGNAATCNNCTGNGNTCCTGCNANCGGTGAAACTAACGACAN
+
')'&(*"#!)*(!)"'**"&#)&)(''((%&"*'+%#(&$)&+#%!"(
@r6167
CAGCCCGGNTTCAAATGCTGCAGCCGCCCNGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTTCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATC
+
<G(3!H?B#!,)/7B>*,@EF*2><*G%*?3G-8107A9>80(!B)(G.<D5%%>?.</:3&<4-+"4G4$8?!$(!D,&=!+6?:&6B)*@<1F"+B0+?02+..$9:+A>1$/*B,"0:B;7&%16<43G(5FE'3-=8C@#!#8#&8)8D2;#"AE1#3#
@r6168
TACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAANTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGANGAAAAAAAACCGACTTTAGAAATATCAACAGCAGAC
+
7?89E=5#%F;8C$1E&7F&&6A3;4%D')9@$="?($;!C(<G4A0?+-B<(/H(H/H=$74DC;$,71")A0B%=B09'0D!-&G)&G:;5,?-9=+20":=8H3>-2=;H"<!6D/&7G'+;+*C&A!)A+=CE
@r6169
CTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCNTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCG
+
88'.E$%=7'CD2%53/@?7B/<2:>#%25@<"8/;)"D0.!<-5FG3D(4B>D*9)5/(%4E-A+.3E4.?3CC6&*".!1-H1A0
@r6170
TACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCCTCTCG
+
@%!&#+C'@9C(0A#&$F6$8;@:$25B!/B@((",)(#=H7,,=F?8/,(8-!C812+0;E@<G0=#HD3-9!+>4?7'!2$?99CA3<&C"HGG>+,H(A&0
@r6171
GGCATGGCCACACCTTCCCGAATCATCNTGGNAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAATCATCCTCGG
+
$D#3,,A$!+4D/&429>E,/2.1<G3%A+%0*54%;(7+.F=)#66,3=7G9)9G.*)-&/H(>G8(9$681,/E>@7
@r6172
TGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACTCGCAAGAA
+
5.)0EEE+&.(=&-GA55,!1&>;'*?&7%*;5;<2G*9*'?"8#D
@r6173
AACNGCGGAANGNANNGNTNNNNAAGANGGNNGANNNCCGANCNTNATTCNANAGNNNNCTNATNCATNAANATA
+
$$$$#$"#"$$#$$$"$!$!"!$"!$$"$!"!"#$!""#$!"#!$##!$"!#!##""#$#!"#$"$$"#"$$"#"
@r6174
ATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTGTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGACCGAAA
+
46.&96)AE(3@E84B)0<>2!HC:";5*C+H>'-E*,3-#;A:/=DHAH9/<4A@E3:*-!:.>0-&-2197&;<A,?.:;'?//;&;D,5:HF,E$>A44$6)&24H)!+H*-2$)HCH2&107;'(/3@1E&';(F*9(C&,2'!D38&G54"(4,=+(#D6FF@F&.9%#47!.EHB+
@r6175
AAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGACGTCGTCCGCTGTTACGGTCAGACGGNGCAGGA
+
D*@%1:"9EH%H2'B/C!1F"/D;!"0ED<2FA7'=A=25H(6B@;."6=,">DF)7'F"0,2'43F<8,'(D6G5#!195=8(4
@r6176
NNTAGTNTGTCAAAGACTGGATGAAAACGAANGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCCGATGCTGAAGTGAT
+
''#)(""&&*+)%*!")''"&+%+"$&%+!()%!+##%(%$*'"(*'%%$(!*&(!!+!*&(("##(!$$#++&#"($&(%$$+(!!##%&*)(*&)+(+!&(&)!+%'(!"&($(+$+%*)#%
@r6177
GTTAACGATGAAACNATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGNTCTTTTCCNAGATATTTCGCCGCGAC
+
'#&+"+&$(!$'#!$))$*(!%+#"*&*)$*)+('"+$%+)!+)'"(!+")+&!)!%$('*$)((%!*)%&!$(+%#"+#"($+'**$*(!#%%*')##!+$+!%
@r6178
GTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCA
+
3(,:65"+E!EH4?G/>;0@>)8E*).F,1/5(+-DD0!),%"!/71=$>.F""C5AG"9/*5
@r6179
GGACTCCNGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGNTTCGGAAGGGCAGCCAGCAACAGGCCGANCNCTGCAATGGCATATTGCATGGTGTGCTCCTTATT
+
/D+($?%-5$@G1)&5CA"5+%!9!D-#*DEDCB7-:DH&2D#:2C9;=++::E1:=*8,)3C,5*""68'2(>>&*F@H8'?''&-HE"/5GH@00H,=@?B)8(A=8;D#,G7:0(A6*!-C@9$&&/5/'/'0<;$2<.7"
@r6180
NNTNCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGGCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATAT
+
'!+("+%!'++*&&%%&#!!%'#%%#%%*&(")%"%"&+**#"#&%'"$''%"+*!%"$&$!()%"$(&"&"&()*#+!("
@r6181
TGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCC
+
0%50C."&C'A*8=&<"+$+&*2C3DG)6."7+':B,)DH-+H3/&7!G.&AGA3B;)E.E%H7'B%%"6CHG6C4C+92"C-
@r6182
AGAGGGTNANAAGCCGNGGCCCCTGNTGAGTCATNCNNCACNGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGNCGGTATCGATATACATTTGNTTGGCAAACTTGAGTCGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCG
+
'%)'%*($$$))%(''!&(*"!'')!(&'")(#%#'"!(%"&+"+*"&(++*(''"$($*&%'!#()+***$+&&+#)+!)(%&*%(++($#'&$'$+&)#%)$+"(#"'&#$"$)"#$%#%(+((+%'"(#))(&($)*+"())'&++("")+!"*$(*&'&)+%"!*))**+#&++""+!(!$+)"#+(#(+$'$%%%*+*$&"!*&&(*'++
@r6183
GCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAAC
+
28+#-G;#4%:)$G@8!,<-=/)%:!=0$#2$9/AE'B61G-->-(6277@$1<.:8)A?")>0.9E
@r6184
TNGGGNAANTNAAACTCAACGATGGGTTAATTCGCTCGTTGTGGTAG
+
""*&!((&#*!$($++#*&"$*#()'$&$)+(+$(!**%)%'$$"&)
@r6185
GACTTCGCCGGACTAAGTAGCAATCTNGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCG
+
F')9,6A72DGBB7;2$-+#+,+(;0;5:0:7!25611%>2*@<%:'3@+6$'49;A=%F7B*(2DA%A4E#144173*6AF#/-"2>A)481?:H:
@r6186
NTCGATCAAGTGCGAAAAGATTTATGTGAATNGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACG
+
"%*)+'*"$)%$*')&'#*)&#)'*&"&"'%"!#)%($&'*+**!+''()(*#((()'(+%"&("&))$(!!!#*!(&&+%&'')$$*%+"'+!$#((##%%!%!$"+("((%#*'&'
@r6187
GGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGG
+
G9B;-=."9:@!BE78>$><"<HH.0"B<82#.4>H77E;3H@8'9(80@)32D0/669C1#E,*==-G>/
@r6188
GGATTAATCTGTATACCTGCACTCCACGCCACTGGGGTATGCCGCANTACACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGT
+
>@.(57:/A5<=C/0@"!'B%#'D)<-<B,E,5F-*%EA/#?B(:F=GG#55<EF3<G&?&F=1/$:2)33E7%!B-+:%2;.*.@,CE:>!*BB54B&>11-661,5"(*1
@r6189
ANGCNNTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGNGAGGTAAACGGGCATTTCAGTTCAAG
+
$"(%"'#*+!'(&%##((+!#$&+$"'!$""%+++'"%##)$"(&"&++&#*%(##*%#'&''(*&*)"*%)&(*#!%$)'&&*%&&#+#'$%"$%*$%(*#')
@r6190
CCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGC
+
7<<3?*"71F=24+:,#:,0/!4EB2-2%7D?G>3H5!#B1C8@,@-C:493&6(40%8%'1'?3),>06"1=CG300$"0B:-,A1-
@r6191
NGGAACCTCTTGCAGTACTACTGGGGAATGNGTTGCAATTATTGCTACACCATTGCGTGC
+
"+&$%(!&!"'*!)(%($*+%''*$$')#(!"')($('**+)!#*%$&$%**&!#)(&**
@r6192
GATNACGCCCTTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCNAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTNATGTTGCTGCGCTCGATGNAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCCTCGTCGGTTGCA
+
+8H#74$E3(9*1&1?*"+8%?G72@&H(#*/7"B9!0@3*EEE.,;4HC#;7;=%::8'(:5</9#>1:/-B??G47+?)/C.&8#4)G/!;-/?-H89?5:+%C&;%75&"%9E?,/:5'89F+7>44,%7:<7@46151=FE'/8</9*(22EB4F%!3G@G0#@;$,556:=DG"@3"=)CF4HA0("B6@G&6E/
@r6193
ATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAA
+
#H1>A2"=*2-+5,:D69C:G":C(F2%=*5;66;@>2/%E2?<$"1830#4//E835+3,F+B-2&3@:@;#<64@#*8.?E$?)(1B+0'>;+-D1@>E8)"HE7F<$B1,<)$A-DAAGA.:3F.4A?,8)5*EF:;4>"87&G"3*5225B3-1@$H@58H<F$;#,8-,0"4="1-+$2D7*4B2>(.!*<-*G!%/)GD*3)9,F9E6:-E**22
@r6194
TCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGA
+
>%)@1G,28%CG%%22(E+;*</EG&5G9-1D7,+%".F$39H=38(%<(<-!8C92645B*C5E99)<3":1*9)6>FF$&".!(D9;-@=:#8+C2..29;7881)>="@-1/!3<)(*3?3*.3D*)G8"9?-:.90'F72'4=-18.HHH
@r6195
TCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGG
+
,9'17-<-3B"?EA&/<!75G=:+?%B-$(?@3$B:7CA$&53A:.&B5016:F+3=5,0-(.)%82FB"G0F77;356>*(FF7'3@HH>=&9FG7/!)$=G
@r6196
CAATGGCCATTGCGGCNGCACCAGGCACCGCCGTTTTGCTGATACGGC
+
<$:A2*<7.4!5*.,1%$1*+9-C3$-DE2%1076H+D9?CGGA504>
@r6197
NGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATGGCCAGAGAAATCTACGAGATGAATGAAGCGGTTAGTAT
+
#;=%/40=814BD5@3)=$$607"'9*FH:D#!D$G$H#)H!@!40E20$>4357D9<8*9,D+2>A.)E(%91/9+C4/">*3
@r6198
AAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCNCGCTTCATCGTTAA
+
D5D$6=-?'*7+9&%84,(E#E;H17)A!%9#:-C5F:)@-(4@C5+D#-$#)
@r6199
AGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCNCATGAGACTCNAAAGCGTAGCTTAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACCCTCTTTCCGGTACTGATGTGATGNCTGCTATGGGGA
+
+$'+121G4*)95=3EB69G1=5D&25*6+@&$5C8(,=;)$=H/:(*,EB(<)EF9*.8-;G2<!:?817=A7<)9!*)4*/D=9$2=;80H6*+#$/5,.055GE2><0/*D)&7@%#160A8H9='6!876!"&"/5*69-/CA?>6!HB/4.:%"-()--.9
@r6200
GATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGNCGGGCGTGTCCATATCGAGCAGAATG
+
GAD9/B653A?:B%F!#E7%D96#=FC*9F6"/F42)4@E):7'##'#GF&$!E@+?0F%,)D#-A/
@r6201
NNCGNANATGCCNTANNAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGNCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCC
+
$%&!!%$$$#*%#$"!#+%'!'+&!()")#)+($'!%)*"###*%%"!#$*+"+$('!!*$"'+"*#"&(&&%#'''!*&+%+'('&(''%*&"
@r6202
CACCGCTGATGCTGCTGGCTGACCCTGATGTGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATG
+
3&A%<*!H@1<-70=*#6#B&&DB@$B85/"&A'(!,@C/+91++'"0?/+3%>%'.;&0B;5>7D)D1;B?H4$7D!FD17'"@;80#</336CC*=*%(,4(F7>'</=&33D%(<D;C*(8F5$&:5A29@%/7=0H1>)*8,%()",H$;'9D+>;$A-,@;51;9B'4>%FF@<=*)B,E-FC525:+D+7'/G,G,A-=E60$/D@!1)'(+7F376"D
@r6203
NCANGACGANGCACGNGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAANTGCCAGT
+
&)*!$"%"&$#!(&$+'%&*&$%*$$()!#)())'%+)(+*'!%&&&%#%)"')*!#(+)+"'*%'#')#+*$%$*"%+)"%")(#!'"'*(!#%+&(#'**+*"'
@r6204
CCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCC
+
!=>2'C#DE*:?&E)B"5@(E>#44A)#.8B+#70.&2FG&E%@2/:0#!7)=-,(B>=.A@$.HH3DA7=A;<4G-"H-
@r6205
TCNNNCTTGCCTGCAAAGATGACGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTNACGGACATCGGGAAACGCCAAAGGANATTATGTACCGAGGAAGAATGTCGCTG
+
)##"$+*&!('"'%%&"!)($)*("("&*"&!(+)+"*$()+#)'%'&"%#%('!!&&+(!$!"#$(+))+&!(*$&(*)+"%+'"'&!&#+!%"+'*&')+)#!!'($$&""%$$!"&$)#%*#!($
@r6206
CATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACAT
+
1E0D2?82A.F)$1+,4&>$2#'9F595%81@3=/:2&!<<56?$;2$:%HH9EE+99'>0/!6*-B=?0)?4#0-)2#FB6!"38466H=7&).&="H13?,6F<?#3D>6+2,?=3&E**=1'5-2?A3B(&?8
@r6207
NTTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGC
+
#);7CC55"(82-6)2"HA2H691G-,C8+79'12!BH:#?)A$14'0FA/B>'%$3#!('>C)4F5;@('=)!;;F<,.(*E*3@>8,.)@1H-<2"@&E0H&6B@*B($9D6DDDD/H4H#&2(@/:<2G%+=0A:.B0BG&5GC-DF:9*8F/<:'DGG84&B0GF+:8'C320?A>+>0-G%#!D'73'1(
@r6208
NCTAAGAAATGTGAGNACGCTATGCCTNTACCAAATCCTACANTGNCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTNAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGNCCTGACGCCC
+
#25D::)0(=:)60:H+1$?D5,=D/;3AH"5=*:/,)>=E5D85$1C=/**55*9F4*E774E-"<"23"97*)=,G;A-BB;?ED>/;<:.8A-!-=/33:B.E,8B)@.09(<A7E8H&G.*H-B1+(E:C2"=*(">,B!@?96DE1.F@?%3$>1:3
@r6209
AACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGG
+
H*90'?*;16A6)(??@0&-F!GH;"5F>-3759%9>E=BB%&/&5G'8:F@#'2&F?9&H(4</5<9G$#/3.:A.'CF9@6
@r6210
CGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCAC
+
=18=-+1;$;047$G#-"%&3<66-*?7**21*4'(6!':!!;'B8&$=
@r6211
TTTGCCTCACGATCGCCCCCAAAACANATAACCAATTGTATNTATTGAAAAA
+
;)6FC%@=>E80>&0":A#4&40$E8>D6?"'2-DG+0C@9/!H%:;CB88<
@r6212
CAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAG
+
6.';?CH6@3!H%4A=$.;91F)!(E:36$*H%++!#:0/$D8*
@r6213
GGATTTGCTGGTATCTATGACAAGGACGAAGCCGAGNGNATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAANGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGA
+
:BE5.%>A=>(70!C0")'&#G:A9A":<41#:9G-&8&$A2,"/3=,;H$5#-:!A75,C<5=>?3=H,7GG)F/!4E"%B%%3A;:%*H+*/CE&D"+/06C&)16:950+>3AF(E'/%82;+-!334'CEC3CD5+CA8)G*,(E?4G3?@8?3GHB1/,<0'!-!+5(;4"@%,65A8',<3$8757%'!G#@6&7%CH>7)0?9&,")9)&;3.16(
@r6214
NAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGNGCTGAGTTTTGNCCTGAANCTGGCGCGTGAGATGGGGTGACCCGACTGGCGTGCCATGC
+
"D>*E:$/<H#-5=,>2$?A&C=D2H9,+.F7984H>DHFH23A2='#-+B*'%29'(9:#7C9;G7+E=!6&*/5E'#=D)2G<?6%=9790
@r6215
CCGTANNGCANNNNACATTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCANGCAGCATATTTGATANTCTGGCGTAACCATCATCGAGATCTGCCACA
+
)"'***"$%(!"!%$))#+"'$!%)*%$"((&$!&"%*&%'&)*%&+#(+%&!"+(%$)$$%"%+%&!(*(%%'&)#!"$+$)&(#)"&$**%$$*&#!(%)$*$+$$)
@r6216
AAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCNAATACCGGAACATCTCGGTAACTGCAT
+
.H5'580&-#4E./8F2(DC3()"&8,@&E)655E!.=EBAE(B/'<D6*</-'?+,:D'('34H,1?@#
@r6217
CAAAATAAAATCATTANTTGATTTCAGTTTTGTCCCACTCCCTGNCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGNTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCNTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAG
+
;8#2@=+3:6;#A=9#//&>04&3?3=%H!.=-6&E#H<#>:8<<!%G1032?+/>:)*:94))&:3E.2%&6*?7B/,518&<D,AF+(A)),=H$9*:>?A>8E65)+:AB9>>58-59.3%7?E:!8=4&H':E:5;"3;58>!%DG<<&&06F4!<F4'0+B*2)339-/5=8@?AG$->+:9#@28EEGB7D+-46.>;:-&*&B%#@HA18GHG9@:6A;4@3*%9(GF'1C&2#64F/#!-+H#5D.-E0"&*>C&=FG,G0@@0E*%8%8A304:!#A0"/7*8>>:E1;)"7+D1%@H3@@*C
@r6218
GNAACANCATCTGGCNATAGCAATTTCAAGCGACTTAAATGCANATGGTGTTGTGTGTGAGTT
+
&"&("*#!#""(#"&$%&+&*#(**!")"*"%$$&%+"#!))!%("(!$(*)*))$&(%#!**
@r6219
TGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCAGCCAGATTCTNCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGG
+
A&#03$.@A;0?.:E410*A'&27>E)?$'H1>@A('8H+,:?$4"@,$#'?C<4;:C/&841+F!4D*;,)D++!574!<<,..C4/%E"C?C<E#1;$>9(*;0/G:;CFC=.:@#$?%*&.A;0<#>CH!??@6
@r6220
TGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCNCGGCAGCGATATAC
+
5(/EBA$+-"=,@F6(6$-45?<::B,E*:G';B-;+6!+F6H>-@D88CE$(&=3$
@r6221
NCNANGCNNACACGGAGTAGCCGTTATCCGTAGCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCNGCAGCTGCGTGTTCTGCAGC
+
#%(!!#!"##%+)+&*++!+&&%'++$!*#)(*$*$$!""#!&'+(%&!(!&$&*$#$%()*"&&)"&(%"%%(+'&#&(%$"!#*"%(#!*'*$("$#)''(**'&%%*+$$)!"&&+($#+)$')(%$#"+(("!*++'(+))&!)"'$($))&%$%&(!!"$%+$&#!"+#("+"!"'"#%'&&)(#($("*(($&##*()(*!)+*%"!!%(+)*#)(+$#!*$!%')"!(*('&%)%*!($$+(%'$!$'$%($)+((+)#)(&!$"'&'("+!$
@r6222
CCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGC
+
D:52<E5>1H;&!B=/=58/;="'7,?=%4"3;-"A.:3/67&F5%'.E29)628F<3+H/&,
@r6223
CCCGCAGTCCGACGGTTTCTGCGGGAAATTGTTCGACGGTGAGCTGAGTTTTGNCCTGAANCTGGCTCGT
+
(#%')%&!&#*$*+(*")'"(+$***#!!%(%"('""&'$%"("%$(%'*&!'&!!*'"+$#%(%"$%$)
@r6224
AACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCT
+
=9BE:2AF"@@<D3%E6-*8+060++F>')AA"0,(()/.$?/D,D@)F(<D&147
@r6225
ANNTNAACCCCGTTTTTGTTTCGCTTACGTNGCATGCTGGCCACGGGCTTTCCGTANACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCA
+
'&(%#+#&!#(%$#*#"'++($#*)%+*$'+)+'*+)*()%&#&%!+"!'"")!!*%+'#"'+#(($(++%"+#$%)'(&!)**$(('#!&$(#'(&&+#&"+!+(""#(#!*%)&(#%+')($+")!$*#*+")+%&#(&
@r6226
CNNNNATATCGGTCACCAACAAATCTGATTACTAAACACAGTAGCCTG
+
&#%'"$&+'"%'*$"("$(()(&**"%$''"$'$%&(()('#$*+*+&
@r6227
TATGCGTACTGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACNGCCTTGAACTG
+
)&(*'*'$*$+#!#'!$&#*#*'"'")'+*)*#%(#*!%(&(*"&!%%)*$$)('")&
@r6228
ATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGNAGGCTATCCAGTAC
+
&AH"4,H3;G%A7C$?>'=0?:78.3;4&A7(EF:&G>H,$>8<+(283@!&%G)8%3H$&)H.94=#4#<()(%6B.%';E4#,,$'A5:+H@EBG+B-0@)=".E</AF8?E)>-.@+@F-.58*!E8B#0/#1>&CE>?G5-6)?>$/?3-:6$;4!6H57
@r6229
CGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTC
+
#7H33286>0DD)42B#D5D/&(B,71/#F(+7)&<#>!);&:C4B+14HA,
@r6230
AAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGG
+
$'9:/D57<-.**(F9!1(;FA8.6#G+G$07.3=;3?+>=;"=!6"81.-#"AD<1C$0;#.C@=,"9E!@8?(.':7?A-5D=$+6=-D&4
@r6231
GCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATA
+
;<'0>*=F=B+83*)B<0C=GD82*,%AA,,(=A$?*(&7G<>!2(&#A+A,0AFE&,$-<8*ABB5-5B,4@4H=@<A/?B4@@(G5*#+F$;F79D?431.85#;&$EGE09#,F5:6,4/3A.G)D/./&5<*0(24*(&953@;:F(:?8
@r6232
AANNGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCNCGATGATGAGCGACTCACCACGGGCCACGNCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGA
+
*!&#+!#!%+'&("+&%!&%!*&++**"&)#$"#")+&*###"$*)))*#&$!(#))!+$&++*)!*"'!$+'"&'%%%%+$%#(""&(+"#(%+((#'!))('#%#*!+**"(%($"'&"$&#+%'#)("'+''!)*'%*'*"!"(&$)!"&)#+)#()'!'#!"#++!')*)**%'%&*'$#*'%)"+)(%'*'&+")
@r6233
GNCCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCANAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTNGGCGGAACGATGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGANCTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACNGATGGCGCTGTTTTTCCGGGACGNATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCA
+
*!+(%+)"")+*'!#'!*((%"'!&$$%)%&!!)"*&#!!)!%+%)"((&%($**')&"++%)'"''*(&$*(!#)&$!***"%+&%(&""')$!!'"&!"*&$(%&""!#%&#'""*'*()*$+#&$%#+"!%&'#"(&("''(##+)&)#*&#!#%*%%+%"#'#+!("!)+$'%")'#%)")(#+*&&#$($!)%!*(!)#+()&$(+!)%)!!+'$*&*!'#!$$#$)$#("'"$+($%%##$!!+%#"%&*#"'#'!$')$')%%%$!%*#(''"#*%)%"+*)'!)'&%!"()"*+*$+#)$(')("&&*&+(&+%*!*("!)')%&%$!$#"%!)%'+%*'#()!#)'"'#+"%!#*&+&")$&&$))"$*$$!$*'(#&+$&%(+))!+#&($%&($$!$#&+!$%$+"#*!#!("'!%#%(()#!))$$"$#$"!#**%+'"()(&("'+*&$(')&#"!'$#%'$'(*#'#"$&#&('*)$)%(%#'%+&*#)*"!'+%"($*#&!''#$+$$(()&#+$""*(+$+#$$"
@r6234
CNAANATNCTGAANNCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGC
+
$!(*"'($$#)(&%)#+#$!#*$$*"%+'+%#%''%$#%#$$$#%+$$%"+)*)!'+)$!&$&#+&$*"!&"!"!!#!'!&)"$!%+)*%')"$(#$'&+'%+!+((($%)
@r6235
TCCCTAGGACTGCTATGTGCCGGAGCAGACATTACAAACG
+
%53#(-%*AF/).(A61%3F5/=9-*0.H=$F',!-A/23
@r6236
CGATTATCAGCTATTGCCAGCGCCAGNTATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAG
+
H$?8,@FG@<;76?3F%3?H>(2;8##GG8*C<!);"<>">(H@+65=7)C#(6&E)B<+"1G(++D3-E*9:4F0&#74)75EGA+H,47>H"6-F)451(D
@r6237
NTAACATTCCGTCAGGAAAGCTTNGCTTGGAGCCTGTTGGTNCGGTCATGGAATTACC
+
+%+('%%!)!*'!&+"'#%**$$+'!&#*(+$%$%+#%&'("!($+(#+$&#&*'("$
@r6238
NGGATCTGATTCGTGTAAAAAATATGCTTAAAAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGNACATNAGGTGTCTCTGGAAGCATTCAGAGCAATTGNGGCAGCGTTGGTGAATCACGATAATAATATGAAGGATTATTCCCTGNTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGATAGAGCC
+
"A=;FF6-<0E919;.8=;?/3HH'*9%3$;A-;3;7.<&9@0(6.EC;##@:7G.)2;-<7>/?A-?,:5E=701DFF"C/G1-3$F0+6B-F(&"@>)&@-A.CE-=+><=8:#G4(>:@$H?G,+F(F7D@5FA.2=8>-=?'2,HG)AG%F/H#';.H@E))%6=G4GA-*G%04:?9!%<(55E:5?<B/!!?C7C%&&'"-)"G850G,A9#0$
@r6239
GAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGAC
+
GG/9G7GA2>ED!/!C@.8185=GCE26:+?GA0G(!?DD,"9:GD8&A<04*-7A355!-8DCC-67"2A2.=2>7)-/8$'?<)C3:>$85#AG,>1*4'-4<2+F$?E,
@r6240
GCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAAT
+
1$)5H"E;'*C.E2D*;(G<6(EC&6C9>(C/G:;*#><=2&19E9(?6%@"'B=!F$
@r6241
GGCTGCATTAACCACGCCGGAGGCGGTCGTGGCTTCACGCACTGACTGACAGNCTGCTTTGATGTGCAACNGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCAT
+
=<50*1$=$;0&<==*@;E+<'?793G*'..'A9-&,,?6=21?>H>:4$<%*F/GAB:"4*#D&@<%'/8":!,HF8G%/F=,%/:D2G&4(903H78'19():,4D")4A-3BF"7?8A-,'>170AF*4/8'64C(%<7F?*D*<)/$;->")="#%C9A1:2/)3.8*"@+G75(%
@r6242
NTACCAANTGTNCNNANNGGTNTGACNTNTTNNTNGGNNNNNCCGGNNNANAANNNNAATCNANCANGCGATNCCCTCANNNAGGNCNNNNNANACTNANANTCACNTATNTA
+
"!$##$##$!$#$!"$$!#$#$#!#!$#$"#$!#!#$!!"!!$$"""!!"!"##!!$#!$$#$$"""$#$"""$"$$""$"#"!!""!!!!!$$!"$!$!!!!"$$!$#$$#$
@r6243
CNGGAAGCAGTNGNCGNTNTCGATTCNNACCATAACNGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACNGAAACTCAAAGACCTGCGAANTAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGAC
+
)(%%$"*)%&%!$$)(!"!$*$$()#"+#%+*+&)+"##+%'!&%#*+($*)('(#%!+!#*#)#+%&'*"'#(($)&%&!'$$&+#&)('"!(%*!*&'$"#!!((%'+!$)+&&(!()+**"&$'*!#!'!(&*$*++''**#*$)"'"&+%*##!
@r6244
CTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGGATAGCCGCGNATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGG
+
/9@2'9G$-$A=82:-C!2F+945&D.=9""1;;:@;&@(!3>7(+*;)D=8.0%)/!:;!7;/2<2F/907(3*!/92<HB/>G=9"G@G)&"3@+1@E-?02/#<D#)B?3+C30=D'!6@B#7D$GE%A?%/5>?=-@&D<A;*1"68<#C80663$G:C"7:"*&#'69C('?7;C10F-
@r6245
CTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGT
+
.7"E(%>2),7'=#HC4BH93AA8->D08/62.+>4/"1;3:G!+,=
@r6246
TCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCT
+
B2-44G=27+0*$0++*305C0%9C(/91+>=F?E5')%!*-.304"D@(C5+7+?23.!52$9:,H</;;>"+9<)=&#'2C;9,G99'4H!(%5",.
@r6247
AAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTG
+
D3E3D=5A74>3C7:HEF,.&D/;$96H?>8,&!"9"C,A267%4;*-62'D
@r6248
ATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAANTTAACATTTACAACCTTTNTAAGT
+
3/0FD'7$#GEDG5/5/$=GD<#(*4:,#2=G5F-<23+;!.H;HD5C0!F5"-)F90+G>+9@
@r6249
TGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCC
+
B>21=@224CG253*&-5;"286H1HA-0F$3?6CC0-FD,.##BH!#,;8@D:><?$2<%
@r6250
ACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTG
+
((+"%+&"#(*(!"#(!&#(%()&*'!(&$))($)&#!"$$(!#*"+&
@r6251
CCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATG
+
E)2+?HG4?%<!F8:#C/=(.50((44&4?;-*(@#:?A;)5;/$6!%//+F7&651<->FB
@r6252
TGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGA
+
+2,?=1?9#3G71@/6$399>%+,G:@;:%0CG->*(3&0D-D6'/)(
@r6253
TTCCGCCNCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCANCAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCAGGAGGGGA
+
60%2;F)>%(B!F8>(>3EG%>;+7GE?8E?/="'F.<?#4>+$"8:?%<A&FA<;1/F@%,'F4+BF<$#<F8E=F:")H2"%?A5%1(78#=FB-("<;!:1"!)!'A"84B>,D%-DA1?.,-ECDG08&<)"1$&AF%/<(017D/3,,"!,&).CD4"B3$9)%/#1$7$0>G=*"'+7?(@+3A1C+#E60"&=145),G15>"9:>56>F/*0
@r6254
ATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAA
+
H6$:9/&*8.->@7?0;2>'//#8D$@8<5'&1?:C!G-71FA6;*D6#+24B>=87&33-&'7*'#./7;2>3:?G/C8HG4'*'/?F6)F-%<15G;>F7254F"?;?E+$1
@r6255
AGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACNTACGGTTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTNCAGGATGTGCTCAACAGACGTTTACTGTTCAAAACNAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTCT
+
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
@r6256
TTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGG
+
7*9D/8@2.;8FE*9'D16770<5<!:>2<;B=$F:#.GA;>4CD+$:@$=$9;D72D/2>8"!9-"C&3AA<-'8G0H/#)=/6+A1.>:&5G/(/>(@&H!D3
@r6257
NAANNNNGNGGGGNTNNGNTNNNTTTNNANANNGNANTCNANNGNTTNNTCNTCNNNAATNCANAATNNANANNANNNGANNNACNGAGNNNANNNNNNGCTNNNAANCNCATNNAATNGANNN
+
$##$$$"$"$"$##"#!"!"#"#$""#$$##"!$!#!#!#!"""$"$""$##$#$!!!$$!$#!$"!#$#!$!!$!!"!##"""$""#!##$$##!#!"$#!#$$$$!"#!#!$"##""""###
@r6258
AAAAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCNCCGCAAGTGCGGCAAAGACAGCNGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCNGTTACCGGACGAACCTCTGTAACNCACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAANCT
+
$'#+'*#)*#!'"%&*&)!+(*'##+&)'#'"$%'"$*$#+#)'!(!)"+)#$&&&+("#*('*)%)&+($!"$(*!#(&(!$%$($*")&!"$!#'*%"(")"'"+*""''!!'$"*(*!'&($!%%!'*+)!(!!"&(%*'&)*(!#(*'#%!++*''$)!)*+(''#%%))"$++$"#$'*)!"*""%*(#&"'#&##!#*''&")
@r6259
AGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGNTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCAC
+
DF+(*G0-&)>>6FF8=%@%>,8=!9D"H7:GC31$@&D8+@EB$0?A6%118**DE/A9:-E&<CEDC2CGC,!=?%H51&E*-&-@G.2*=&>7,75)5>')4B#/)D8:6"<D=;&&#.%B$.&4G5.D1"
@r6260
TCCGGCTGGNGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGG
+
7!*5-1-.118'/:.),6.@.=#%,7CD%D582)74!8()=C&:!8.!/
@r6261
CGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGNTCAGTAATG
+
-($H>,$G7=FA.A?44&.%7;E*5'DG*(B,;D@9E8&6:,-,<,@?#B';@C5.$<H?8@8%A'"GE%33/522/*%1)001$/A<1$),#
@r6262
TTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGT
+
(H-,:(2@8.B8&H:.9>33/F84""(;>4HE")-@CH!0=91,=B4&2(<
@r6263
GTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGNAAAGTTANACGATGCTGATTGCCGTTCCGGCAAACGCGGTCC
+
&'.A<")*7./&7D*3<F16B"29-5@?%B8*!6)65'!F:?*)&<,61-?%25;60B'>:;B!G9G;=@F3%!8,)BC.E8
@r6264
TAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCAC
+
8-#+2A!*=6)0B%=$#F;@1>**5./839#@E3"A(83-".)E+::!
@r6265
GATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAG
+
?8C'AFD&(50E65+#4CE;0A.-(H$@.%H0F!8)8B"+%3,2&#=>A$@DDBE0F.E9'0=$;1H&3*6BC?#01(HF0*9=FG;;/9*=F
@r6266
TNTTGCTTCTCTTGACCGTAGGTCTTTCCACATGCAGGATTTT
+
%&*+!!!#)'$&%"()+*"(!"&!"$$&#"*"***%#)'$&()
@r6267
CTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAG
+
+#()+$%$+'(()#("(&%"!+)+#%)$($#"!$*+&$&'&(*"'++$!"''&!(
@r6268
AAGCGGGCGGAACGGTCAGANAGATTGATGTATGAGNAGAGTCACCGCGATTATCTCCG
+
16@8;.8>!128%@0@)45,<D=>,!B;='5=D?/1#.80%8#'+G+@<'D3-?E.!-:
@r6269
AAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGT
+
6"((=!21:;C.+F/0!37F?B?+4ECE,1-GH'C"1*?%B2:F(C=#-A%B""&F<16A/8$@?@D=5(=
@r6270
CCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTG
+
9>GF-996"41>;;G>/1/.'!;@%5G&;B89,@:(F740(D"DG$561
@r6271
ANNTTTTACGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACNCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATNACCCGCCACATCCACCGACTTTTCACGGGAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCA
+
"$"'&&''(++++!($"!&'*'')*$+$!+!%"$$*&$)!'%')#+*!"+)(*")()%#+"(&#")"(#&%)(#(!'%'+!'!!)"'!++)%%%"!&&"**#+!!*#!('*#"&&'%&"+"'%%#+('+#('')%(%'%'&%*+(%$+$""'"*#(*(*+*&$*+")!+)%&"'#""###+"&"$(!&'+##)+#+(&$*($$)"$$(!*$
@r6272
CCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATNGCACGCCAGNCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAA
+
*)2*8$$B2+@462?%7+1(34&$<:?#0%D&#F'8<*5"E6(#+2=$#F"':-A;2C9978:3A+010+=6C:,DE70C!!(*)"E"2C!*:GA=><0>"=D>$!,-C7>6F%:,$9>@'"A@%@%>/8@<:<C8ED:<A-:('.;H(C6*3179E3<$H:5*>2:#-54%6B.'D2-G'%F?FH!3766?29)9.+E=*%.
@r6273
CCTTTCGTTGCGGCCTCGTTCGCCGTCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGTGCCATCGCCGTCAGCCCCGACNTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGNATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCG
+
0=88%'$!'%7%15-/4'.BA7(A'?A$FC;D#E:4;!$4:(/&*!@!$'EB6--<(496CH"6D#9=%0'D("<C4<;-@48=D0%5!B255(!-(9$@D6BH?0!+FF,.G#'=@>!6"<HF!0)%B+/)7G(>33)33458+F?F=BA+%,'1C.*,C)C,+CB7,@B5!!GHH?;GG%1%)8796$-'>:.DCA(-.ED,E5%$,#E7>66F6!CE$A/59&%%,*)B6<G*HF6E!
@r6274
CTGCTTCCTTTTGGATAACCCACTGTTATTCANGTTGCATGGTGCACTGTTTNTACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCNCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTT
+
)A49+E/H-8'(,(H'.**<?!(2/=ED+1E-3%3:%?B&07'G..%%),9C$FH)3-G&;#==0DGD?(+3E$0;.,@=4(!1G+$>%F<>4>'?#9:,-GE=>1B*H4(C(%2#B*!'A,&B*%.+#$1)@#?;&567%F63GD+)992*9FH3E3%-C:"-(478"@HBB</
@r6275
CTNNANGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCAC
+
'*&("%+'++(%&&)($&)%$&')')$"%($")$+&)*+$#)$+"*"*$)#*!)&%%+"!$!%(&*+!#(%)#%$)$%%'"#!%#"&))*#
@r6276
AACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCG
+
*3;8)(A01;7H!)&26B6;8$.!/>&0(#+*(D3:2'D58&H;15)?G840<)BH%=>7H-11%C?:GE9
@r6277
ATCACCTTTAAATGCCGTCTGNCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCAAGCTTCCCAGCCAGCGTTGCGAGTGCAGT
+
+G&(G.+C#B=6)=G:/#/(D7)5HC(DB'?#"/9G3&3=$93(6H+##*H4$&979+0'-$@;1B4;%<62::H7%671")"E/!18<-9:6=DG>"H0E69G<,>B
@r6278
GCATTATTCACCACAAACTCATGCATACCAGACAGCCGGTACACCA
+
6@0=E+)$><@A8BG890EHE8H9E2.&/C%:9.$.!H92>AA;=#
@r6279
NATAATNGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTAT
+
"5/A26G?!E.!'<1DA92EC!F22-+!G@=9>::.%,93858H?46B)3D'$+(BH<F@4*7A"(>557<+AC@HC5F>8#:*)3(/<1/;B
@r6280
CGGGCACACTGAATCATGGCTTTATGAAGTAACATCCGTNTGGGANGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAG
+
C;4&<C'E2($(-$&E<D1G6#&8(EF&,;+**,/4D!;/8$2#A:FC@*>=::'5,8,:B2G%-;E7.!?EH?1<->/+%:0(9"-C.96*$;E7#'$5@<6D+*+&AA!-B5?56)F1H:3E)0&';@:>67/?E3$;2D2H7!@)3B@7C!*"H9=,*3G85D3B::&3<@
@r6281
AAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGT
+
>0..5:1&9?4=(>?93H%;H@!E#&-H)",",7DA8H7.574A*F%#7$GC,8C@4C%;;A/F5.2<8,.11:/6#&<A$7>254+
@r6282
CCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCANTGGCCTCCTGACCGCTG
+
:=6=>06GHGC>H<6.$0%G#-##&+FG*+G%-'C*.>:7A3A$>BG.:H:2.&;90E"?37,7;*A8B2F#3A!4,('235894;
@r6283
AGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGT
+
/H7%$EA&4C!%.E/0,&!-3:-5*F>'3G,#@F4E'*H0F'H=('B+9<3<:"-710?/D6;D0--:82?;64@=0=)28E
@r6284
TGGACAAGGTCGCTGAAGCCTTCGGNGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCG
+
/5)?C"4F/F1&3A>B(&EC0@&@)?,!!2(?+AA5%"D47(B;)$1%;E6H/?G7(D1>"7#:):57)>A!DEC=0>1-/+<>
@r6285
AANCNTGGTTGCGCTAATCGNTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGG
+
'&!()%(#$'"&%**(''$##+&&+'+)$$++*$*"())%%%%)&%#%&$+$"&)($)+*)"+!**)"!%%"*%"%##((!!'+'!*!)!%'$$&*!"$%$##*!%#*!&##)+*!%*(#*%)$
@r6286
ATNTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGA
+
&&!>6DBA"<C%E''.,GG),-;$=9#=6GFC2-E09DG;G/08D-/-=$H387GG
@r6287
AAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCG
+
6((/$?:B5<AD265@/-E/C55#5/>6BE+(B-/$0'"5B7!!F-/6<"?/6$:,G)@*D
@r6288
TTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGNATGCGAATAATAAAAAAGGAGCCTGTAGC
+
AH@*;?1-46H/.//+?3=%?HB(C@?6G)GC;<4.-%&#C:3&460H:3%(/C=@;:=)2406A+<22>3>9.9&(.&E;C61#3"-H),3?%%/)?78)G.%#;!7A
@r6289
GCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTNACGTACACCGTGCTCAGCC
+
*'*+$!*"#!#&"%(+)++*%$%+$)$!%)"*+!*$$%"$#")*")+&&$!""))#&'&"(*"!(&()+!)+)!!(!"#%*$&$$#%&$*++"&&")$#*#'()*'$%$"'')&)&'+)")#%+$#"'
@r6290
GGCNNATGCNAAGAAATCAGCCNGCGATGCCAGTGCATCAGCTGCTCAGGACGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTC
+
&'('&&!&(")+%$%)'*)$%*%+'''"%"$##+%+*****#"&#)'!"%()(($%!$*"##+%&'&*(&"!'#!&$"*$$)&)%#%&%$(%!#)!!**(+'
@r6291
ATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCNGGGCTTTGTAGGTAA
+
-'A.)<$:9F$'?%+)8E#8#E&>>5$;:!<@"!49)*FG(C21.-8<,$$(3.<!.#'2'
@r6292
CTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGT
+
/9)).472;!;%.48/?!>=F2D>-?74$.9(=0<#B,8!B*"
@r6293
ATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATNTGCTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCGTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATNATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGAGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGNTTC
+
@G00%'(:/.+5F8C*"9$=5,.B)E%+2@B;:7H.<5:24:GA!A7-'%1?9,+H$&5BA4*38&57?B2$GF1C,84.,<F+$4":0"%7>=+#"<A"C'F);B>@>C91,86,9F8-.:-6<(112=;9,G%2-/G>>>,*>'=G@1(E(3"/+?<-@9@.<C$@'9'8%//*41*5D'D3,C1?*(=$.C#';&6G-57.044+,/,?B?::+EG08GAD&'C!56>!G+,D0!C,B;D<5A<&C'1)2,//!-?G')/%H!$3HF7:!&$#60=/CA&7C<$*GF%.F?$33/<)%7D07:($,9(4FEG"%(@G*G+4A4G2:@'?CD/'C:A2-H8G,#>%$E@1F(250@1D;$#>!1"%#+"#"5@6(E0/7.E='0.!*6'7"D%(<%(.
@r6294
NACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCA
+
"6!;8.C=-35%8<9FDB/,.F#'$0$)F)0#>27(C*;;:4?$5#A&3$%'ABAC!?"C42,06=2:<0!5@4";CA30<3$6
@r6295
AGATGCTGAAATATTTTAGTGNTGATAAAATTAACTGCTTAACTGTCAATGTAANACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAANTT
+
.C$=5>,((56&@-%A2CA;HC;D:*;&!5<%+)D4B8@1H<?4="0"5(#;?16;045?#D=A%4%CED),'38?<#-"3-?4D0B:1>+(1-'=5&9+;EG$5)@E72-*(+8:2-96"A%E(&&&B6+&B&3:&@C.8,1'*<17A83<E:,>,;+E&
@r6296
TNTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAA
+
"%23$;&0"2@F97,4:/A$>!93<3&F?,:360B"99/7
@r6297
GCAACCGGAGGATTTACGNGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATCCCACCGGCGGTTATGTCGGTACACCGGGNAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGTACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACCGATGCGTGATGGTGG
+
;182F#E/;?3"-)&3EBE1AH%>:.)*7.%B9"8!*-@&?G.065'?=.6D47/2D*.<,A7#9D/*DA)?2%6AC?+$7&1>:/4'--!4F:&;%E/61&@%;EB"A"9:?A"6.,;-;!G=*$(9&,#"@"/*!?%A;63>1<F%<;;HB%0E4!A:H50535.D),A4,D>A79B68$AG-78H":-E$,BG?F+41(H/5!@*+C3BB:5#6(0!-3B?2'%$G%2AG5)HF>7?)B-A'*CDDE;'"CB(.A((43@';,A*9#D;%A#@F6!E:88""?83<#',G&<H5+(.$E!139(5::466(%9$%@66<733+#)**9=(?
@r6298
AAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAANACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTNAAAA
+
G0('44&A=E;G!7$3D'#CB2<(3#,)C7$39.2!77B+9)$///+2=<F'A)3A&,A32+B:*8.E4:(B;-G"7'B6>>'3G.7@*!/-H38>4FE/;A$4H(2'
@r6299
CCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAA
+
4G))*<1?!8D9@20<0@C=&=44)HBHCHBA:#!3$+8C87!<1=<"+!G9G>1+*;
@r6300
NCAACACAGGATCTCTCTTNTAAGTTACTCTCTATTACATACGTTTT
+
$=;54(4A#$20-=)05?-<@$A$?0!:+4H"$49"7,"41G/&CCH
@r6301
TGTTGACTTCNATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGNGGCCAAAGAGCCTCGCTTTCNGCAGCTGTCGGTTCCTTTCT
+
1D%4*7D4==!/BC>FA(%)'4-8!H,&#7*>,4=$?$H9@$<5'7:<#&8&/#1?*.=B&'7F.3;),0G.)7,?7$EB))?6B:3%-,9F;<F
@r6302
AAGANAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGG
+
)%)%++$+##%$&*)&)'+""*$#%+)((!!*!%#!#)()&!$!!&#!+!+%#&*"+*%#
@r6303
AAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCGACTGGACAGTCC
+
DE.2.'E*@=B7.%H"4(:5/F&)AB7"'CH!:*)'(2&-9*9%".C$C>6%C)9
@r6304
GTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTNCANCGCATTACTGATCGTTGCCAACCAGTACGGCCT
+
DD9&0?(G;8<)#!"90DF@E624E/%7-#-%>$.4.+2'<-:)"7#(0?E;-D',E'$1@6'H!HA=>>,0B"!"F&0->"E.6'&6C;D"F(#5+*F>A4B!?7!A,E"!E)>,!*DB2H
@r6305
CAANATCAACCGCACGGCCTGTACCATGGCAATCTTTGCATCTTGCCC
+
?:"'2#87@<"5B#7?"D*2@'4&)!/;:F/0(0?A<,+)D@?)A.-+
@r6306
CTTCGCNATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCGGGACGCTGACGCTNGNCCGTGAAATCAAGCTGCCATCCTCCGGTACCGCGCTGATCAGCCTGGTTGACGGAAGNGGCAATCCGNTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATANAGCGTATGGGAGCT
+
%(')))"+(!""+#")#%*!&"((&%$&+"&'(!''#$('"'*(!"$*&"("&)%*!!*)$"'%"'!&(%+"!&'+*'%%%#+*$%(%!*"!"!%+*++&*)%($($"++&)!&!*"*%"%))+%"!(###%$#"*'($)+'!'!)++%!%)#*)(+*()*!(*#*&$($(!!%&+("+%!!$)$&)+#''%$'#*%+('!#)%)**$"+#+(&#&%)''!+))&#!(&('+++&(#&&!*)$%#+"#')+*""+#!*()'*(&*%*%##$*%!$$++"
@r6307
TATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGNCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGNTTTCATGTTNCCTGCCCGCATTGCGGGGAGGAGCAGTGTCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAA
+
/F4%:,.A.;-1,;'H,"/8%*:+2)+;G-/.>8827'6HA&.88$536-.@H-'!E8!%4GA(C<)D)(35.,<0@*H!0:7#(F'&*"G#C78";)E/%HF394:9C#?"@<5D>!.F%%?B8"@=DB?9"(0)'6<1/D*"0"0+B5D.>$>2!=?9E5#:-6!#:>@E;4.0$E)G.C2@&&*:G>,$B)&A"#./?.H76,6!G,?0/F?!1*1='&&-H
@r6308
TCAGCGCGNTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCA
+
3,D!>>2E-(?&18F-5<$D)7G(8&"?6?(7?2%4;EF=6'5#@)->/,8+$@G&E,H%=*%H@;867<81(C(
@r6309
CTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCG
+
6'::B<2H>-#)6<<>@055@-A<$A4C::6-0%BE47"4=,>3?#FE394F%3F7-<'9+6-C,$9C-$2.9>0!&/8A=&C*(<$C$5H0);-8+2@*"HD8&
@r6310
GGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATT
+
/F.='F,=9,</;0B-+&'EE9;$64<-1"<%!!BE-0-0$C5B@C*08&=3G+6@?H0+D/42)5C*5=HEE=86>'B0B2.)H&B,>D<&.8H%?87@"8$")*<A.(3$+
@r6311
TATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTG
+
4,C&51$$:5H@*;;<B3")@=)E9!11"$(F9A5@@#@.A,)";#H0?55==!D-;EE.G61>D5?1#A5H?):.E="20GC1@(=E7;7&!17?C(.>,0D%1:&!1&F17&.-H%A%&2$4FC!=F;'+44.,%H,A3G.13:7.*BG.-4'@(C??/C@'G<-$ABG1)#92F1A?>@7B!&G.FA$.:?%!"F
@r6312
ATTCTNCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTT
+
#'&&*"'+)$'+'&*#!*+##)$"'&'%!'*"'**#%"*!#*$)*%$&%')%+*(*')*$!%*+")*''!#$$*'"%&+&!*'%!**%%)"#'&+
@r6313
AGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTG
+
+%('&&)&&)!%$&'*"(*$!)'"$"#*#$'("')#"(%#!!(*$)*%&))%)+##"+**'(#$'
@r6314
CCNTTNGCATTCNCCTNGTTNCAGAAAAAATAACGTTCTCCACCGACCTCTGGC
+
((&)('$&*%*)"(%$&!##!+&%($'"&(*'%&)&(&"+#&$#!'&!$"!)(*
@r6315
TGGTGGAAGAGGTGGNGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTNAGGTCGCGGCCCTTGTGAC
+
9>G<9""6;B=&(8@A4$-?2B.1%">F;>C'>#9.3?)H<B(,87A':<#2999!<&%C%=2F=+?/$<D1+H5E.G610F>&C6+.%#<8&H3C80/-(-'%9-DC+$;A
@r6316
TGGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCAGGCGTGGAG
+
&>#GE?5*!5'44.%3#!(5B;<&>/5#&2G'180A1F)8(F&5G*6)0<+E)3?EA)%3.E*C#G;(4/"D)G"*C.260E8=9;
@r6317
TGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAA
+
42@)-&.0A66B!=A+!$DG-B&/*&)3/+G>'"%5>>15G"#C6$88>B2.:5.F*>$#:H+A$7"2=;C23/=>60+C)2<@
@r6318
TTAGCAAATGACTCTTAGTNTCTGCANNTGTTNNNNATNGNNGANNNNTTNNGTCGTTNTNATANNNNAA
+
"!#$!!!#$!#"#"!$###!"#""#"#!!#$!"#"""$$#$$""!#"!$!""!""#$$"""!$"$!""##
@r6319
TTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCGTGATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAA
+
$H.A9&,(!">141D.4-B5E7+65-268=A$3)5*)'**)#)"DC85"?(FH/@(.,1H>:#*<!/+<!23D5*!!=%73GE.A++H1;H;$'?#'0)65%*-E!B5<H(9:$"&94H@&#,$"-?1<),@FE%.;)D<?EC
@r6320
GNTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCNAGNAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACGGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGNTGCAAGT
+
;-G=596+?4F"<1;)(DF-!20(,<$&AH833B)>3D7!FA,,3+B?;5/#$F3+=G.40"0)@'71::@7A-6.%B$72'=-G028HF#E:%8$-78CHF)+-@$BAB",%H/&,F58GC&3,.A"48F*FE):"//4"84#'-G,10+#,!)A)+B6,(0H5G*B2>3<:0'=;H#58H'F-'$"'*4(0;7'D#D<!9*0@!;@+)2C3/>5F$D82'F"<%7'F8D70>>4/@=2!8EA**%'
@r6321
TTTCAGTNGTGGNGCTTCGGTATCGCTCTGCNGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGC
+
"$&*#)!!$###$$')+$&++!+#(+%$&&"")+&'%("%#!#)#%$#")&)#)$&&+&)()(*#&%$)%(!$!&+$&%+&&#&)'"$"'%'+$$$&"%(!%
@r6322
TTCCCCGCTACCTTGTGTGCAAATTGCATGAGATAGTTGATAGCCTTTT
+
,CH8"E7",,5*&"4<>7?(%*&A3?3'(@,<%C5EBF4792-B=HBD"
@r6323
TNTNNGTAACTGCATATTCTGCATTAAAAAANCAACGCAAAAACTCGGACTTGCCTGCAAAGATGAGGAGGGAGTGCAGCGTGTTTTTAATGAGGTCATCACGGNATNCCA
+
%%'$!*'+*'()&"&#$#*$!+$)*'!!##"$!&%+&"($***'$!'"%$+)!$$)"&"$+&'&*)'*%!#)(*&$+"!(+%)&"'('!*'"#)%'*"*$&*$)&"!*%+!
@r6324
NCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGANGNCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGNCNGGATGCGACGAATTTTCGCCGNCCCATAAAGTACGCCCAC
+
'@:0!H!(.2'+44*-%;$G=*#:+7E/4G&BG?2@>DE%3'G3*9.F<8.8$E&D/<9('<;<G7!#)8/)>1$'C-)53)-3;,;BD7))/7=FC7#&%.)-4(@);:!(&/>=<)B88&=)7,,E<.9@1A?!8&-#!5+47A'@,18
@r6325
NNTNNNTAANNNNNGCCNGANGTNATNNNCTNCNATATNNTNNGATGCNNANNTANNATCCNNTNANCGGAAA
+
#$"##$$####!"#"$""$"$$""!#!!$##"#"#"#$$$"$!$$$""$!"$#!"!!"$#!#!$!$!$$!!"$
@r6326
TATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGANTCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGC
+
.E!7%%',F0"C&9=*.7.3>3%H4.74;&E#<057"<<-0*HH4'<G.A<+/02=C:*+%(<.95%03E8+)8<D.B>>/B#<3<.;0@?++>E&C'//6#D=0:$:9:2;0E2/@:641#47;DH6H8,9511;2E%4C*"27E.-259:6DA8%*<-9==3>.7)07DGG;F0'45<(,&3(%F6'BD
@r6327
TGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGG
+
C(1);G5,-4'HE)&G24H"+">:7A81+/H0?5E*/G$C&45'@H/:-62&%9;4G-(G/</H:;&&9>8)ED)@
@r6328
ATTGAAGAAAATGACATTGAGTTTATTANAAATGAAAGTATGTTAAACATTGGTNTAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTT
+
0,4"5F*0$:6&?@#!E:*1>+,;5':=2A72E$-54,>!0&.=3(-<8>F3'+F%<=$>AC;4E;95/$)EF<1E&@'&59@#-"14:(6;2B*64D>24
@r6329
TAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGT
+
C)(<#6%#5,-A51#8!0H+1%1%@.A64DED@5!F?6HC,?,59HF1;,!9)&/HA*#8"<#.B%@H,9,.0!#4D)5(*&F+?AF83$<5=0C9#,8@.-@
@r6330
GGGATCACNCGGAANAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACNATTCCGGCGGGTATAGGTTTTATTGATGGCCTCGTCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCNCCCGCCCCCCATCCCCATACGCGCATTTCGTAGCGG
+
E/*)-.=AE7*(/<%D(:D242:A#1E$D:494(2,DAC,F68A8&(G(16$A9+?:>#8==;B80),'>0"F,7>10+C79;330H?CC#?E.3>($?&+)9:C1F)02@G"0/+'/3-&.8%.><?%$1<#9C#59=@!BGC)A%:)8*EDC9=55.,!6+6)7-7"!/4$F7;3@,G(4971*>!><B!124890"0"@B>@,AD(52"6=>0#FF004@>1B)3-"2C$!(/$+A#*%;"A91:7,
@r6331
TTCTTATATAAAGGTTAGGNGGTAAATCCCGGCGCTCATGACTTCGCCTTCTT
+
+#*)#(%$*"!()#&($()'''%$!*"#$&)()*%(+!$)*("*(+'))*&!"
@r6332
AGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCA
+
(B9&1+,4!,80@:3(<*:'<BCFE3:18.#!;17?G%BF2#&(<?6&2F<?*@D;:6/0846-$">>C89#9B>$@
@r6333
GGGAGCCCGCAGTGCCTCGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGGGCGCAA
+
+)#)""+&&))(%%%'*#$$(+#"!!%"""'(&#)#&#*%&%+''$+)'%'&+(#(+&'!+$"*+!#!!$!!*'()#'$"'"##%('+"&%%)#+*%#$+"$'+)'%!!%+!$++($+)#"**&*!#'#*$&''
@r6334
TGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTC
+
<??3<EF%+@G'>="#9%$1#0/39B2EC$%%,0(A*4/G<3"*7.F>@#))=!&&:86(*;G;C<;84.#6@+!3H(+@0
@r6335
GGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATNGAAACGTCCTATG
+
;@*?"'G4'E-A?)0'%"+8"*.FG$8,--B)(42=1%,-B')C-G;*3@F@'
@r6336
TNNNTCTCTNTATTNNATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGGACTTACAACCGCTCAGGCNTTTGCTGCATTTTTCCATCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGG
+
"##$)*#$%%&#$#'#+#)")'(!*#"&#")%)%*!!+!!)'!"()%'(+&$*)%$(+$!*)#)*!$'"!'!'$##"*+*'$)*))#%)%!(!)$*))+$&)))''")!#!+*!)&)&%!&++#''(#$(&!'#*))'#+$(**&*)!!%$&+&(%''%$"$*%
@r6337
NCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCAT
+
&>>8<?E:634009>2@#7.3<$%!#&',>2-5$7E2960<';"6D)<)10::)5%0*7:++.5.2G50!*",:$,-)%++5"A&.'%#;'6+(92*&C!@=E:G0?0'!-AGC<>#1H&7E4B:8<=;0$CA1%;::='/EF<*+-)<:BB-",&*(#'<G$A=4
@r6338
ANNAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAATAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGN
+
$+$#""'!*)$'&#$!#("%%%#*#+"$$%(("'&"#$#*#"&+*$+"&&'+!+'!)!!!&''*%$(*'+$&%#"$$'%(!##%%"#$#*&*+'))%"'%*")!'(*)"$!*%*#+#!+&''!+($"&!(%)((')(!$!'&+%)$"#$
@r6339
TGGTACGTTTACGGTGGGCTATTCTCAAGTGAAACCGGGTACATTGCCGTCNTTGTCGGGCGGG
+
+$(!'*)("('+%+"))+(!(+)&)!))+#+(!&$&(++#)#**'(&*%!&)(!"*%)$##%**
@r6340
AAACAACTTCCTGTCATGGGCGGTAGNCCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGANGTTGCCGCGCTTACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAANCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATGATGACCATCTACA
+
/.8,=(3H)351F;E-F.G7)%6*/@2'"7H-$/H6.33-A94D/2".%?;2!+24>'?+3.1@?(:$,D0'C1H:5$)F;;17,*@>6$2>)"D566DF&;'&5D%(8B;(3%#4!*/>#14(<>$.53E3:273484.HH>;44DBF<6"5B%>&2>A6,,?-@?!B(!@1$7<#6>EC=+0?E5G"879!-8@"$$CG:8G!7',02602*/E6@%@*.*!!?&,A=C:""'9)D5H//"B.;0/)""<32%-+@@?><)./*;/0,).@(EAG00$G-+&1G2,612H-9*"1E82/?G'(<G4471";GE*;AC>G6$89%FF:8!H?A9?7ADA0?+7E:(0>@3H6(4-#+8/H(:@#5%7"4$/5'5'#:46%712@5$)!GD%/''2;"&D2
@r6341
TCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAAT
+
BGA"0H2,=#C7#E&(A>*5B*@1&>CBE"9+(%?&00E1'->*8FD:'D9A.,0B91,,5*G,9=;.+@/.@(&@C/7(B1$?,/,><!@!5/7H!1D@)G1C;1)$9$B6+FD'%<<D7/=.?=/1#B29#"DE#+/*)
@r6342
TCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCC
+
>HFD:A57-)<,B@58+,+$G75C-E.@$"H3&@=6%4G#&9/*2F966)D>%#,=F1>?1&E1,.7DC11/1+-<6!8*&>9D(7#=F#G0"E
@r6343
NGGTGGTTTCCACCAGTGCCTGTACNCCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTNCGGCGGAGTCTGCTCCTGCTCAC
+
%&'0(?0.9BHFCF&/)DC44%2$=4@G#@29EA#-31?A0#8-/@:)'?9$0!&B?+!(@E/;"$/!=/&#(:.4):,G&>,@E>B"#?=/.B&".-#.**=3;#6*.E"-1:-+05C/?:$DA"+82D&E0CE9F+,3+F2/>'(.8>E*@7)'!<=-0,(;7F>
@r6344
TCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTNGGCGTTTTCGTACA
+
;%-)9:;A77E5#97C@C@1'>1AH=+4=!<DC%CC8>5A;-720>!'--#*=)+.%0">&#1C?C;>.,H.,"!>;3'<.!H<6:4A<8DA6-%$H"(
@r6345
GGATAAATCCGGGACNCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCNAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCG
+
B91%H,,0'28D5)5,+#6,#!F/E=%.>C;7.D>#=96"::$)4@9(-(!,6H//5H+C./=@'C3F<"6:2.H+6G+43$#;+%C>G(4*-)G-!G*%)(C6/3";1$8"DC?F4829&A4EGD%.=7@%);/'81"&.<41#,F13#&3H*0;74F;
@r6346
GNTGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCCTATCAGCAAAACGG
+
%#FC>H!9(1:&55(@.A29ED<D$,;>C?43?H&>"%GB7;:@E19E?&'6;??,/E<7"%4
@r6347
NCTGACCACTTAACNCCACGCTCTGTACCGAATGCCTGTATAAGCCNTAATAGCTCCGCAAATTCGCCAACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGANACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCNAAGCTGCGGTTGAGTTCCTGAATGGTTACTACGATTGGNTTG
+
$+78)E+,@6H%.A*.2/.4#4">?D$?&4,<E8B5-F?25F??>&)27$3+"9,!0@C7*0F4>-160;;1"0B3*,/G6,!<E=E/71'#,#D0H>//02A%='%F!)'3B4+@@G"D%;/D4:&$-/FDB>'?$H082#4")-!A!+?17-G+-?*=-245H$!;'HC&.<A5E8A8'@&A11E$%""+EB.7/<)+0B@;3&F$HGC+"@,D$&+$+0#6-*:=='D"-3D8C'B@.$4+$6+//?!:'&+/6=B16##<H)%F0;E5<239:-$4%B-7$C>4:=7*B-=%+6"4
@r6348
TTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTA
+
'C&E(+0?F-F-@3E?3->5!%>6&2(9>(80-#9<A=7CG>!"0,959!/A@!7F-$18
@r6349
ACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTC
+
2+4)2#2/H$2=&F"#'=!"><97,=E2'%&:2HFGD5*$CF;C(476-3#,(.CE4<4474:F)CB03+%))?-)(;E/%%=('-%FE+6&H+492:"%<)@6B=<"+6,->-6=47A/4;8
@r6350
CNGAAANCCAGACTTAACAGCACCACGGTGGTGGTGAACANGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTT
+
&!!"&$"+&($&(%%+'*)('+(!'%#$(#'++%(&#%'*$&"!"+($")%'&%+&'!%*'#"*$"(''%"*+"!)(%*$%%#!*'(&""*)$#(!#"+(*!'#"#"#%&#(#*+($$!)"))"'$+#)*&%
@r6351
ATGAGCACTGTCTTCCTGACGACTCGCCNGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTNAGCGTC
+
&&#+)$)!&&(#+("'+$'#$'$#%"$**'!'"%))'$&&+#%'"%#(+(++($"'"*'$####')%)+"&
@r6352
TNACCANTTCCATCATTCCAGTCGAACTCACGCACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGNCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTNAATACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGNCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATNTCCTCACAGATAAAAAAT
+
)"$$)'!+*)$(&!'%'(#*&&(!&+*)&!#$)+"%)%!"$%(''&#%+$'")(%*+(*)#)+!()$!&&(&&++)&#'&'$#!)('!&*$'*"%("#"$&'"*!!*&&#!#"%!$)$$$%$&&*#!%%#*#%##*%#(&"")+#%!#)(!#'"*#$"*$'#%&%+&+'$#$+#*$"$&&!('*++)%&&$'#+%!$#'"**+*)")'#$'+*)!$(#*"#)&)(#$!"'+'#!&$##)*&'!""'"(#"%))$#!'*!%'"$&)%&)&)!#"&!'*$+!*!')!"&)*$*!#
@r6353
AANCTATTATAGNTTTGAATGACTTCCCCAATTATTGGAAAAGAG
+
"&"'&+)!!)$###*$#(!'*"%(%$'$'%(#$&$$"$(()$"!%
@r6354
CCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGNCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCANCG
+
;:92H',0HE$7!(%@<ED/>,@*?BG3;*6H>B/F?>960::))69)#F'>D&"(##9-'A.6>F=>H!>E5GD!8A<@0(>"(B>))02=):!(,A(G%16>AD5$$
@r6355
AACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGACCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCT
+
,F&'@<C152(%F9:03/'F4D(A<)28*E8B8!%8'*+3FA2E&1?=C=7B$H'>/@F8<8D(562/E0)3+E&=)A=>EGG+,&6>B<>/@@=%/D-F'22!(,D8B&+FD7"+.81BE%5?A
@r6356
AAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGACGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTT
+
@BC8&A6);@3006;F<)42*&>-?"+09F34/+2&;0;'/7BH:,3G,F"G/G&30?;.68C&'#*C*A77DB4*@@$H%>+H=/#G"DB:$/">C@3*(>DG189DFE!E-/@9EG?>F;HBC(8%C+."4((F1%>+$
@r6357
GGCTGATTTCGATAACCTGTTCGANGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTT
+
=@2>/E.,2<A@=";./'&G.>&2'##5$DH$+F6')?-163*1D);G/!?3>BD*5#;()9HEC)BD.>?3&8=.:AC(C*!,H;1"#.%;?7<CF,DA.>&)%13;'E'6!<",./2+=B>?
@r6358
TATGCCCGTATGGAACGGGCAGACGNTGACGTTCGTGCAGGACNGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCNCGCCGTTCCG
+
%DCA9:4D*A)608/&)71*>"#+E8)49)&.::F!0A-57<H2'16>53=##<6!<,9H>!)E63'5DC$<%;'%@)=71.36(8!#=B!!03'<0-&89.DA9-C&3+.+4!
@r6359
CGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGTCCAGGTCTTTCACCGCTGTCTCCAGNTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAATGAACGGAACAGCGCCC
+
4">B+*5C8#'=72'$EAF0H</+$7=%-3.<19#>BB2E/%4305/)@/.3=D8&HE/AD9@"2?.D>!B*!'66G06!&9%)!96)D2/=)7H;0D(CE,B6E#-%-58'+="056;14)6B72/2,D6(7!-$.>5&$6=G2!%4<H<H.70*$=85,#77(,""
@r6360
ATGCTGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCC
+
%E&8&F:A7?5'-?9H!32B'C:%(;#2.48*@117BB0;A#'B,0&E80G:38&BH9D().-,=."EG?'1
@r6361
CTGGCGAGCCAGCAGGAAGAGGATGGTGCAGCAACCAACGAGAAAACACTGGCAGATTACGCCCGTGCCT
+
)+'%%&#!+%%*+))$#)+*+&$!%()"#**+&#)'!'(+%**(!(+%$+#)!+*&+!"!()%)*"(&!'
@r6362
CAAGGGCCGCGACCTGACCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCA
+
,+/3/=1<+$+)@8$F?+E88%++$)#$@)C::D26(.9';!H?.H'##=:(!#+?@D8D.@3>H+4&6C7=F7')1D!DE7:.G)/=@,DG'@)(EFDAE/$9%6F/!<G2:)#:3/=2D?2)H?61+<-F*?E>,1&&:%E&!,
@r6363
ATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGA
+
96)+C>;+%&E+;B1F</23C::F;0D;563+4C/2C4#FGEBA>*5"<5,=H=-$*@-$70#A1:HA6"6;45+%/D*$#429?.+A;CECD;06G;2)E+@H5!AC$E6F(F.'@F'&.&<0>FD26%E(5#A0;,D#E!#
@r6364
CNNCNCNATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTG
+
*#!!#%$'+&"*+#"+#'#&#%+$'&##(+'$'$((*!!($(!+!!#!!*((+())%&
@r6365
TTTGATGAGGCGGATGTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCC
+
47ECD02%)/!7=,!?+<3C<529;#GD6B,933+=4!BEH(-$-,CC+6(07+6FA'"$D/*'>3G'$7/3H#=:#?BC';7*@263/3-A4&#-A.<5-4E75*8?30B0=(77#4GC*>=5F>(2:/%G$880B1;<G1%/1!'A1,"B5B/:3/"*&$1/<E2DB5E3%&'-C4$:!<*B3G1+:;?;G@F<?B6*$,=,9&3")A+E(A--)??<(6
@r6366
GAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGG
+
2:<695B'?-''4E(D//B49B<4*:6?D"<@G7!=+-1D$01&*?'A))#";6%/H'!%9<?$'H09G:#74$+F5G>,6!=1?15:HF
@r6367
TTCCTGAGACAATACAGCAGNACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTNATTTGTCAAACGCCTGCCCCT
+
*$"%@3"70>?C32(>/=0A%+,4:978($<5,A"4-6:F06-<;D/>B+"+;F-9.&B.3&30D'#5/4>3D843F22(&"='?$68C-#+49HG,*GA>=<AH()&*-11#A='5E'8(F
@r6368
ATTCGATGAACCAGAGGTTCATCTGCATCCNCCTTTGCTCTCTGCTTTTNTACGAACATTAAGCGACTTACTC
+
"<:50+E+/&?H-1>88EH<5AH!-?*063'*(5;&0D*EE%=:=FE-E$H>+"%($:+"A!60"H4=239'H
@r6369
TTCGTCTCGGACGTTTTTGCCGCCNTGGCAGAATTTTCTGCCGCCGTTGCCGNGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTNCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGACCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGGGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACT
+
(%;0/#9?2&?&'@0$985E4:!'99AH;H=2>/8/;,9%5&=E-AC(9/8F,#&<F&6H@5=!A=>GH?0*D';2G03;5'8)'!.<7%457?C&.H#!H6FB6/*!1("..%1H@;/<9:$A5'#(C*C4+%38(9DF!1C"")&=.&;@#>.#$(%;'2B23"41):38'$+F,/<7'=<=6)=9F0>/"=(CH$2D+'B5'+$BC(<'=,#+E>;B/55.<//FF"2+(?+A2C(7;,AD<.G:5'"716'2-D7B<H8=8FEE3.A,2*H+(%4!1E=;F="D)7H->50"@B!$'H"FGA==++.+#:22(:B-%G(;'%B@6%(@E&%6%"+B5E-E#!C*;)1GH.<-/43A>717%AFB*<,?HC%G.=26+=().7C'/2&H,B'?-4'12/C$)1'(.7!;;C**6)+*5+@>DC-GF+<3/#*D0
@r6370
NAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCAATTTTAATTGATGTTTATGCTCTCGTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTG
+
#1(E,54":9/C"<C;#.?>.@)2:-*;3!GC@42)4:;6<0A60@A<*64;:,F>77:(?$9C>#1,1)6;"/2?>0DB24;59E?&0#<2G=43;%+@)4;$(7;H+?-%AD$2@!'&<7GC;.#3#*$7GBF1959AH7!A&$)??@8</3)4D4(%C1-3#H;6CB9EB/F>1>HA?%359A8+-6:5%D%<H
@r6371
TGTACCCCNANAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAG
+
=1$,'&*0.C>8G7%C;<F'@!:5+H%9)"56#-'4@-/=>)&?E0'BE45E6'&!-A4;B.5,&E?G:<F4)6+)"8E/F'%%)6#B44:
@r6372
ANTNNGTAAAAACCAGGNTCGTGCTCATCTTTCCTTCCCGTTCTTC
+
))%$"!%$+)*'#(%*'#("(&(!'*(#)%&)$$+&)+($!*'+'$
@r6373
CGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGC
+
/)?1*)D,<#B5$2;G0:1;D#!H?(BA"3,D>40G&H'+%:9=*5;!>!@9F4
@r6374
CCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGNGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAA
+
3E.%4@'/:>A!:-HA@:(G2/@:+0=<F%/#2C06.,E0+,4B4.&'&H/*-)3A923,H/<9.H*/0/>",)8!,%0F'$"/1670,?9C&=5?:@A<6FE?-,1-$":F6*65D&)6+EH+7234'9C1E&73C48:59BE0#3-+B($9193,!&04<E:!&)&91;?58+5-!0D?,&2E@@@EFF092,*)8"/<A5&69'G93H.65+.!F
@r6375
AACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCCAAATACAAAACCAACTTCAGCCAGT
+
AF+A('F)H7&8&(/<6=8*G<<<+'#3/F2:*/E;;(55'6*!0/!)(GGC'13+/&8,,$4(10>":+>"*6C1*(&')F(3!G!;=2;=A3&>
@r6376
TCACTCAGCNCACTNGTTAAGGCGGGGGAAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTNAAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGNGGCCGNAACGAAAGGGTTTNATGACCAGACCCGCCGCCTGAAAGAGANCATGGGCACGCTGGAGACCTGGGCAGAGAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCG
+
+<6!>.*+4,B4A:?;G6AE>.779-5D@,4H>AA@/@4A(8H9>G"!CF77C8B3>9.H%696$';5E5)C0.63+&7CHH'#1D$*1%$F;8:#6>/?!A++)%*:+9"B-%0*G/D+--?A52("G)7FF+'=<HED<(6":1HG,E<5#3(C>=&.>%@/6;%1)%5C8DC<2CG<:-/02<':>;H."HG54.B#+,CB3#&6E.$4>-$.@!7<"/?B8>:F;+"5D<92E>B:(21#"4B*?'!0903C9=71@7=;0;-<9D,%<#1"4D/2'04&DG.-5":8(;%G#D07;1,H66:(A574+F?;185.2@,FF!53<.+&,</&,C))+;0@)=6F?E3BE)2.F-8%/950>D&39.
@r6377
TGCGGGCCATGTCATACTCCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCG
+
A,3(2%%G*$#8;=>4:+73)5!D'-/,3#C=D'H-6,@;9=(;FE=$'*(2E/&&7H=?6C
@r6378
AGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTG
+
7C?G.D7A#B,9DG0+!+%''F>/.C1D<?'*="461'%3"6H?+::*E46#E=6DF,+?&>3@"H@.!A4F+-'BAF$FBG2'D$!8&!'7#54)7HF+D&E8G->D4,4)"'/:<9F025+&0!?C=%>)"5E,?
@r6379
ANAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGGCTTCTGG
+
*#B5*@;"$E5(&(8H&"#C.2"-G(1>!D%'564<H8!.$0%(C24+5'A*6=0
@r6380
NGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGG
+
"4$E<G*F,'7HBG#<7!"#1(')*&9"<4,HHD+F*,+E
@r6381
TGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGNCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCNGCA
+
D)";)!+/.2!A@("<A:@G.F,3@1#(H).G)+@H--,+,C?0B33=21BBB%@8"<A$<+!"D:DB4$!4A561.H3<EG0E,&)F@.3,()C*@;@E%'':%DAF,#<3:G>71+4!?=:B5F8'?14B&&@.97%BG-B(D(0B*73HB<EH
@r6382
AAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCANAATGAATATTATCAAGCAGNAAGGCGGCATGTTTGGACCAAAT
+
:2DE17'%1'//(C*,>/8!%D2G@/+/2CA#A#C.!<9&!%@H@"G?%C5->>?D%9:/H"!5(!1(E+FF10C%*42D=G)#9=!DH%
@r6383
GCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGTTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGNGCCAGTGCATCCG
+
7A6?&H'*H4(2.8A*5A#,9)%D?BC#B,%/G64D#HG$:)485"FF25./D-C=92/*61)!H41'4.B=!$4H<5-0C*31(@H&?$*F$10&$GAGDB::"?)!-3'#.'B25)!309A)AEGAF(6E>:.A-36C3AD$530,+$606)9?+!C701311,)
@r6384
ACGTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCNCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTATGGCGTAATTCCGCATCAGTAAGC
+
')!(+'!""!"'&"*'+!&("+)*)#&()(%*))!&&#*&#+$+$"##!"!*&""'#+!"$*"+!$)%)&"))+')'&'++'*))&)!)++%)##*'$$##'+%*%'#"'"&!))"%&!%#+!*&&"&+)"*%"&++!)%*)(&(&++!"(&+#""%#&")##%$#!)&&$"#$+$)%*+()'!+$()%)"#*
@r6385
TGGAAGAAGAATTTGANTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGCTGCAAGCTGCAATCGGAATGCANGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGNGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACNGAACAAC
+
E-."BB'8FF?/+D#>.#4.@0?**9/,!(8;%*@"?=+.*<F</5DE2-F7:G6&C!"=3EB1;:HF&$">=!@)%)E?8603=7;=%5F-8205".2>!A-;F:*"/=C5),(@A,";'C8F'@G:9'C.(;@/&*@4-(="2,H9C&0)!51!7!=).2:E.D3<'A/C)B9<36$%!5#F%B*)6F39)*.F8=,&8":3,(,E3D*+.1>%9@9=;G;CB(4#!,20;%*"",(B,!8<=;4E8#&*-B
@r6386
GTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTNCCCTCCAAATCCG
+
+'+99%E<484;AA1?):$42@'.$H"D'920!E,8E*.$5@+2A%,6C+"7E&.$:C8D9)2E##2H0$5C?:E
@r6387
GGGAACCACCAAAGACGATGTTATGCATTTGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGA
+
DB@:D.9>>(#,*-@$'F@4/GH45/''+*8)3;(;>$.+58*/@/>+84!!+"A..E!&3<0(:@08&:<DG'G@B;E8-BD&6B=
@r6388
ACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAANAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTANCA
+
+!#'(%&&$*!&*("&!+&'+)%)!)&)%+'*$%%"&'$%'*'&!&!!%#!&!+*+%'&+)$%&*"&&($!%%)&(*%(&(#+&'!*$)%"!''%%&$")"$%$(&)%!)"(&!"+$#!##)#'%!")&#)(*'!(*"(+%"*+'&)"
@r6389
ATGGCGTTTAAACNAAATATTGAGCGGATNCGGCGTGAACGTCTTC
+
'"?E%3(348CE#4D7A!;C?7?;3;F7/HF3&78,035%6',$%A
@r6390
AGCCGGGCGATGTGCTGCTGTGCTGTNTTGGTTCATCAGTGCCGAATCACNCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACA
+
(F"*#:,)#*8)(7DG?1.H&;2.E,&"6;?E<D(7=+'$+1F/=C+CEAFAC,B&F?05=&>E?'<1;946?B,!*,6'!+79@7682)7E77)63"?=(!5-1'E2BF'!"3,*C;3:6,*?A6891#70)+,-:*7"@!<,.<
@r6391
TTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTACTGCTCTGTTACAGGTCACTAAT
+
DC!;!%448>!.;:6?4'EF;834D#++1;.G&!="8=1FFA3G!C:1DB/4!F%F#G6)?)5@1@&-(@!8H.*4';2%2CE6D>,FH-<H;$$=695D*H/'"4+;59/4H(5#5
@r6392
CGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGNAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACACGTTTCATCGCGGCACTCTGGCGACACNCCTTAAAA
+
A++">.8G3C<3118C"$*%8*D.+<C9@6/$!2E$6$(;?H"7H9*3#A84'1(;$>%A@A35#F9*82><<$91!%3@81:&@E05,-)4#E)15'D8?&8%C%4HC:"<(+29D6#8@:-@D;"?)?;:/@*0$@%A$:9B*68"1-F:A7-&CHG799##C:
@r6393
GCTGAANAGATGGCATATTGCTACGCAAGAATGAAAAGTGATAT
+
F(,>28C1<!?C$46;(D.45G>6-.:<4<FH1A@9C%.1B-*;
@r6394
CNGATTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCNGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGANGAAGAGCTCTGTGTTTGTCTTCCTGCC
+
"%!&()++)+*+)"+'&*)%+&!()*&#*+#($"$"!()'&!%+'&+(!*)*'"'"&'%!%*&$!)%$(#%*$$&+)+)()'$%"$%)+$')"#+!++()!###"!&&&%*%**$*'('')%&)'))*(!%")%+(!
@r6395
CAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAAGCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCC
+
>C7C0/H=2?*8D=)*4D@.EB99BA"%9AH4&8#9>*;(@HH&(97GH:1=#9@%'EF$4H,<?1*(*H/<A<:"C(8'4?D;2)$>BG*=!;/)6;7B97./&835=:1!><2/"!#-2)E@#0%8,H?"H4'A;
@r6396
TCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCAGTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTNCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCT
+
@H&=:.!-,31'0)7G9HC"&:&2!-;,!&3/;7$H)?.97"#"3.6AF/"$F,:G&;-B"-5;18=D!+"&+)AG&%*94'%<DDG5,4!5G9F-7)F;7HA;ED'5;%CBG49,&EF,<0/6'?3-(7;<37@@C)$>D7.7CFB(),?9BHC%)
@r6397
NTGTGTTTGTCTTCCTGCCTCCNGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGA
+
!>DBG53,EA!1)))=;B%4*<"83+$744-:(;1C*64HFFF&#<AD!".,B>%.76D/2>@/>(F."<*
@r6398
AAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCANTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCNTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGNTATAAGCGATTTAAGCNAAGAAAACGCATTAAGATGCAAAACGATANAGTGCGATCAGTAATTC
+
2F85E!4,'+9@'H.&8%..3--CGD/%A(BF43?>5D,&'+B,3F&&>*4*&0/2GG'99>@8*-=?0!=2+7+"."/)$$!=3+9DD.E*?F*(9<%'.$/:.,'/!4FE$)E)41E@=>23<8<?B@G&0A4&+ECD9D$*-+$E6,:"F0+:4#E.3.!,='61;&9B;;1)B4*7?H'75A*:$;9'<28>4B*&<!&&+57;06@1A)0)&'44@&74A%1EG;--/('@@-;%5:A6BAE$/B2?$'"7E1":((7;%2<*-"("9DC(B+$%F;=D#A@,@""@.;>9:0/E@*C#')G7%"C?&88*#$2F$8!.-7>A)
@r6399
CCTCATACCGGNCTGCCTGCAAACAGTCCCGATATTGCANCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTC
+
+*0F@>&(#&@0$(@41:E6BH:B;A4$:="#C@G+G>959*:2-!<:G%)<'A1;B;-15G#@DEA4DB%;#92
@r6400
GACCGTGACGCCCGCCAGCACCTCGGTGGTGAAAGGGCAGAGCA
+
12"*7'4+F2)A7D86/)%BF:H#;/"&E'>5D24F&.C):"8E
@r6401
TAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTNCTTTCCCGTTGGTGGGATGCCTACNGNAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTNAGGCAATCGACCGTTGCAGNANTATCTGGGCTTCACTGCC
+
++;CD3H&0/&>)-D>%62)9$5H=>!)BH;@1(FA@*%9C-,45)"1?0<7AF+F@%0;A;*0C3$<2@BH.85>F%:&?;/F!<-GHH@3-)4BB24?;*?2G8$!F&!C%B873@$5&FG)(8?A:%-#):>+(<C"-+5%1#,G+:183%)G2"9@1?F7+56%>((F"@<E)9$9)$3E"<7*-)/"(2D;>B=2;F19;*//@$1#=((0;HH)
@r6402
GGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCC
+
H1$42(9/,7$!1$,E(2.E1A/18'(2EH5A;%,(01<,&(1)%=.6/&
@r6403
AGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCNGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATC
+
!4+,D%:/?8>C298C#,.-*"?!5(A>-'>6<1?6+7AC*;-0;F46+-EADCA?2H2:F0*'D(5>F/4:A#%"E%GD5!<8(>>C2/GA#:=6C.16D7,<.1+=EGD<CB=1H,7-(!*,ED-0H=@7E'%)=0C>G2G$95)HE"!,"*=H'*0'.<=AB5D@->%*&-(-')"-?/#FA.>D!9/A5$&(6<1HB"50!@,3A/?6>
@r6404
NTCGCTCNTCACCGGCTAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCT
+
!=8A:6DE.258B+8;-4EE(:!*>G599&>0!E4G0@!;@F&:94BG67@+A1-><6>AD&
@r6405
CTGNCTGATGGTGCGATAGTCTNCACCATGTCAANCATCCACTCTGCG
+
#@5+<A655=4?(GHC<03D(7E575C8(*"+!82%-H/?DB%6/%()
@r6406
ACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTNTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCANTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCG
+
9""#6?!C0D7F%DF))"$6E>!+=1(?GGA*@62>87(C8!H2%#0,5G769290-?!?-GB#!:G;;'5"4(:2'C=1:,//;+7B7-%><-E:46&B!>9)/E9@*9/7@5=/=46&=.5'&D>C!4.@1G$!7!F,47A.6&9(85*'/@#@C"55'4H+B3)A1/6&C$:*E%4D0!/:<(H6?!6G)G:9'*.0"47<:0A:';$BB'42F6"2">%A,2EB%21<3,7226(.1%6BFE:;3==7>3<-,+3)%557A@C0'FA?$'1D!&46DF$.+F6=%BBF).):;!<F+!:G
@r6407
GGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCNTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGG
+
,9(6HA>HB++E;,>+7(F+=2+*8/93;*,%>()(4C-$3&(@,&$A-H)3F-2G:.#7H'C,8A6GH!$F0&:-('30@*.$65$9$=(6)H;$GG5#F@5@<()#*;).(;-377*0:8(A!C(-#<7;2#"!G@D(@6=3HC2$A20F7%;AAC.54D-+GD+4<:<+GA5"0B4A40-,#0H";$:!!C(&2H.;'.@"#'?2/(?8,>3#;2-''1.F"<
@r6408
GTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGC
+
H-=E7";#+4!11H7@%ACGH75>C;E*0%F616@)=)2G#3D2?>*#7A00'$&<8#@-&?4/C?H)D(F6">G3A'%0?=9:3.,E7?#C4)B*&%1.
@r6409
GTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGNTTATATCTGGCGCTGGCAATAGCTGATA
+
1B/D'E&A-<GF"&FD=7E;BB7=9=H$;7?86E4!(B*0A(4=;D7)'=9.83+7?8,?6->$1
@r6410
AGATTTTCCCTGTATTGCTGAAATGTGNTTTCTCTTGATTTCA
+
.2+,?+)//#)F=5'C;<E+B*?@H&9&5@?7$&A">;=%970
@r6411
GGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCG
+
>.?/&'+;<0CD*)**DF?>$55/<%D$.5.:*)(/=(:-A/=8F8!,*-B*9:6CCF=+<%@=,!>"8DG6A&"F(>E<<.)B
@r6412
TCAGCGGTGCTGACTGAATCATGGGGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGG
+
3'3#.*!5(@:BC7="C,0FD#$,A3><##1(<1-8C(96>!'CA3G;31E);B=?F')5-=HDD33>.0'939>
@r6413
GTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATNTGTAAAATCGGTAGCAACNGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGC
+
64B.&<>:>;+7$3DH@$3/F'#%)//<@!!4>(4GF,A/;-;;A2:@$4A=!>9.GFE?$(E7@8,8*F8$2<1B)C"7$!+9@@&A'BH!4'7DA7B6/A(<0=65F8A"A
@r6414
NCNNTNACTGGCTANTTTGGTCTAAGCTGNGGTTGCGTTCCTGAATGGTTACTACGATTGGTTNGGTTGGGTCTGGAAGGATTTGCTGTACTGCGT
+
'&"*(!"*&!"'###%+)#!)())'%(%#!!##((&$+&'%!('#+#)*$%"'"+#$+&*()!')$$&%!!'+%$*%&#$)*&%'+'%+)##(!!"
@r6415
AGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATNACTATTCCTTTGTTACAATGTTTNATCTTACTGTCTTTG
+
8A'.:55=;"4B';3#8A4/0<2*7,+AF(*?/@C%:E,3D4;3DF958')F4C).'(&.&(:3%-)(+1;&G(E)E,/?!:@
@r6416
CGCGCCGCCNACGTATGGAGTNCCATATTTCTTGACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCNTACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAAT
+
6AE7;:2:1A4EBD$*GF!$?&&$<3,B.1=$54D@2:0)&6##9.,D:"!*'2+'=7E06->54A.(%55/)+-*E.*!=1B)%<!*3>6E!)0&9.5C91A4E8*F;5AE6315G9<95%=>B(ED#3F5(E.HHA;<6D+ED
@r6417
CACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGC
+
!8?$A'*-&79(00+*HD-%:>G?800-/4C%*)G'-<D6@=1A=4*B?!6>7*70235>(C*GA5/&F%=$(GA8"3/
@r6418
TGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCCTCATT
+
+;A4%CE356FG>9"7.A'C'&=G@2#A9+;92#-,A8/5BE8">D5%2)#B%B6G)
@r6419
GGGAGTCCGGTANGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAG
+
2F6?%%+@G(&*?C7!82H$/79$74+-87F<=55F6!;%'3>C=H:2*13,(&81,H$"E6?00G/1G:!,D9%4G
@r6420
GGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAGCGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTANGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGATGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCN
+
;C9(:#4&B2EE'G)?-/.1)6)*<<:)<4"167#C?E@/"<8E<*D6HG0*@>A.=?H1&8F2&;$*+F,?G(#%=>A(<670);5@E1E4(!@C/!053E!/5D3C=:G$=3,?7$'.F;7:#?"?G#+7"-&4$%4EBDACD8B!:HE,$@7976!-H<4&93*"0B-2#F1@FC4AB7@3!+3+>,D;9,+0#!!)/>!!*9>10(8G43)5,"<B
@r6421
ACTATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGA
+
;#$FAEGE1#7>!EA4C=A<,AA@!,D:+?(84*2>6=.,.%B<6B-72#.'35BH1
@r6422
NTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGNGCAGCAGACTCAACAGGA
+
*+&"++$+*!&"&)*!+!!%"+%#%+$$%"))!%&(#'+'&##%$*%!%!$$#%(!*)"$*&%'!$+$$)!*+(+
@r6423
CTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACA
+
,#7;;H74HE&<,D3:5DE87+G)+333H2G9*:,)+B8#7@&F77&&17?E<@5(%B'!91C&@'$/B!D9D,FE8)A?*6"!2//?05F7F2.>
@r6424
GCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCNCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTG
+
"F!A.&3'1B/-'>$'9GC#/@<5A<AF(:3"+#?C&@:@+A4E=)!>8-%0=739!:G.9::8*4+8..::@?F$20;1!?4";!C#5A4%*<@C(95&?-82%("#FC7(EGA"(/@-"47F2"HH29!.6F8,F<#0",G4
@r6425
AAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACG
+
CA282/C:3:A;7-B%)E@&'H0H=H*5F':2<F-6#*!738A!
@r6426
GCNGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTNCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTC
+
$(&4GC;F-$G4@*&:14)#//%;0D,'*6*5C=@!.<)?'8=1B*B=A55CB14@21)*5*F=;"G/DE5/%F0"!F=,*-8'2+4>F=,'=+GF2>)/
@r6427
AGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTNTGT
+
,D@#CBH/?,GF@@/6D+5.D:>H)G,"='DG7A<3ED'?D'9?$
@r6428
GTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCA
+
;8)-":/&15D<")*2=.(2@6)')8D:1!$CDFC#8-9?.B#D("9&7*EC5&4''713DA5,6AE7$=
@r6429
TCGTCCCTGGCAGTGGTCATCTCTTTCATATACCCGGGAGTGATTTCCGTC
+
2D1:AEG>@8F5.</6B)@%(3E35?*?%6E'F."166=+H9#?#16&E57
@r6430
ACGTTCGTGCAGGACCGACCGCCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGNCGTAATGTTACGAAGATGGATGCCTTTNGCTGTACCAGCCGGGGGCAGGCACACCNCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGANGGGCTTCGCCATGTACC
+
-<H<06A$)'*'0!.27=;1-GBE=(#":3/!:.E;:F2%C%B8G215?7+#GD'241=%G8-+!#&4+G7.=#1.D+F(@=/5.,2D5H.B'8@!AA1F:!1$6(1>-,)129H<+*A:=<D"*'423%6-6E.1E$1-#CB5":%..0')C7).,7*<B%7B,60>2)''(%1$H1EF3BA4/)*8$0FE6H36#95-&++">::H%=F"'$B@56+/)GCH#AAGD8B751GG2-%!4H6D-<E/:/6/+ECCE2)$A53,"5;G61*#)*(4FGA>A;;C<;-E0$3)C+9D-(7F=AHD(?C>--69:18!:H=H5<2%G9G.2HG@F?=(1#3,$=F.3)2&,2!!;
@r6431
NNATNNANNNNTTGNGNACANAGTGCNNNANNNCNGTCNCNNCTNNNGGN
+
!!!"#"#""!#"$$""!!!"#$!##$""!!"$!!$!"#!""!"!!$"!"!
@r6432
GTGTGNANNCCNTTCNCNATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACA
+
$#*"(!$!"*$$)%)*&*"++#&"+'(+*)"&(%%$$'"!"*)'"""&))"'"()$("*#*%+&&%*!&#
@r6433
GGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTG
+
!)F7G:C33;E-;/9,,=:;HD#,"=%*,?7;@%=+/)ED@4FF(%>8#E9:3F:,/5.%2..$1C+.>F?EA4+'2GC>=-D)A>;"CF3..E3<74<$6+D?'7B@2>"17F6-0-F;!%=?
@r6434
TCATACCNTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAG
+
/,EB360*7F0$6!54=?)$49C.F8+HA*67?H45("E*-/D+<<%;4&E7
@r6435
ANCNAGNTNCTNGANTNACCGACNNANNCNTNNNTGNANNANCCGTTNNTGANCNTNNGCNGANNGCNCNCNNNGNTANGCNNTNNNCGGTNGNTNNCNTTCNANNNNNCCNTNCTNTTNCNGGNGNNGANGGCGNNTTGGANCCCGCNNNGTNCANNGNNGCCNGNCNNTCNAACGNNGACNACGNCNGNATCNNTNCNCNTNTANNNNNNNTCGNTGNNNANCTNANNNNNCNNNNNCGCNAGCNGGNAGCNGNTNNGNANNNGGGANNAANNCTAANNCN
+
$!#!$"#$!!"#$!"$!##"#"$####"$$#!!!"##"!""$$!$#""###"!"#$$!"#!$$"!""#!$#$$!$#"$"$$##!!##$$##"$!"#$##"#"""""#!!$#$$!#""""!#$!#$"!##$#"""#""#$$$##!$"###$"!!#""""#"!!"#!$""$#!"!!"$"!"!$#!#$!!$#"$$$!#"$!$!#""!"#"!"!##"""!##""!#"!!#""!!"$!#!"##!$!#$$$""!$!#""!!#""$!""#!!"$!"!!$"$!"$!!#!$!
@r6436
CCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGNTTGGTTCGCTTATCAAACGCTTCGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTG
+
(7.;'%-1+*)?06CF?H(CD>%3=1E>,)C-D->5.%&&@21%F@#6F@C*2,&!:#D>C'F'/7,2ED'FH5F4<E5@=HDD%2/$.&9B";+C8(?5/0,599G)E/#;2;(2>,%+HF&8(!0&C90F1#4*5&79
@r6437
GCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTC
+
7=:A$06-:A4G5=1:8.*6/CC1*1;1=C>A%15/+CG!;#4/"@%6D"H"00F*EG4-4";#H
@r6438
NNNAAAGATGAGCNGGGATTGCAGCGTGTTTTTAATGAGGTCANCACGGGATCCCATGTGCGTGANGGACATCGGGA
+
"&&#+)($))$&%&!&%"$(!)'"&%"*(')*)%%()%"(#+!#(#$($+$$(+##"*+)!%!$%*+"""#*!("((
@r6439
CGTTATCTTTTACAAAANCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATAT
+
H-@5:1&;AD+H%:*9GC,2/@<;;H$C!9&//.5>'/96.$A8<0-9'=3E=)3:3"'(14,-
@r6440
CTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGC
+
AE/@G#G4H3E3$)-'+HH20CD>9&?)3(<<HE1E+*H.H7>2**(6#
@r6441
GATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTT
+
C'"$>:@-E-9-;*'&;2%0/$*)'3";5!./4(#344<7G?/9G=A*0#0#36B
@r6442
CGTCACGCANNNTACGCGGNTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAANCCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGAATTTCAGTTCAAGGCCGTTGCCCTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTATCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCT
+
%$$"*$*(!""!+*++!()(#!'""$""*#+"*"&(*''###*!''!(++)&($+$'&#+**&++)%#&'*)(+"%(%&!(%$%+++($(*)#+$"'%"$()&+""$'&%&!"')""#+*$&)'"+%'%"+#*+%!$)"+(&#"('$%"($*+)+*$&')$&#*&#*!(#)!&$&%"'''%(#+"'*%&"))(+'&+#+&("((%#(%&"#!%$&*$!"%$%&)#%*#'''()*$&(&)"(!#)!$&%&+')&!%)#$&%$!")%&!)(#!$)*($%*(***'
@r6443
GAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAA
+
>@+3"61C16(%"(;%66;3$$5*/7.?.22#<.G,&G='):3$&#D()3-/,&4298'25)((21??&G%F'4*
@r6444
TGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAANATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACG
+
HD'12(+@!,5@8E%1D";-96*2B,5?F+7+0&#9!+*/C,+8/*8CD2<?D9@<1D48A-<?5>'&)=:<0H5C?4A!$0@H,05+&%H#?@!F).2&-"1245E??$F!2(A*E@D(GF#1"H8.8.#/DD74;D(7C<:-F#A('2
@r6445
CAGGTGACCGGCTCACCTTTTTCGTTCTGNTCATTACAGAAAAAATAACGTTCTCCACNGACCTCTGTCAGGTC
+
)DC*185>&>>;/868)CB?')/894%=9!A-5<0(51*(B@,9(&15D9D6H57@&)(3--,;%;57+CA+4!
@r6446
CCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGA
+
%*&+($*($'("&"&&#""'#"$#"$(')#$%+#*$*"#&&
@r6447
GGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGT
+
F14("(@3*+.A!B?57>5'EH15FC98$>0?<3>4/54DG439/19'D./;08,)>.:<A=')-<$@>1.2+E$',/-DB8&10E@&B@/1!06'B1,-4=DH8,85!:*<B/#8!
@r6448
GACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTG
+
;6)BF+9F'03$A1=9>GE>&63"$129<C'3G=H$E%96E+0$F8)FF3@
@r6449
ATCATCGTGNTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTG
+
7?D/$7'B%60@<B!/:97H)!(.H$./):-@4/B(B9$=G>/-1<5F//%G911A,*"2$>')$%EA:6>.DH7-5"C-$57C18883&0"5H3<:H)H-<*%7=*%4022G%!;#:B:=>#:C,'C2<:<&4&9>.5!G-:00<>">,<;%/54+D9$?AH3A*B@27@,;'F!9+96;FE</6&/FF):C792;=/+9//A?162!=.7)7406&<6H6",@%<;)44
@r6450
ATCAGCGGTGCTGACTGAATTATGGTGAACTCACGCGCCGGATCGCCGGNGGTCACCCAGTTTTTCG
+
'-9"6><!HE-/8=,!G7H>9H16=1<F&"$<.7+%12F<>=+6F1&*.+(G%"24(*-+?+EA>E9
@r6451
NCGCTTNTCAGTTNNNATNAGCCAGGTAACACAGTGTNATGACAGCCCGCC
+
")%"&&&)!*$*"#%!&&!'+&&'#*)$#$#$(+&'&&#&%")%$()+%*"
@r6452
TACNTGATATNAGATCCCNGNTCCGGAAAGAAGTGGCCTGACATGAAAATGTC
+
#(%!*)*$))$&!*!)"#!%%%#%'+(*(+()!$"&(*$%&()*&)!%%*)+)
@r6453
GCANCCAANTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGANATAAA
+
%*#*$##""(+&+"+!$##"'$!#&&&&&%"""&$##+(+(()))#!#"(&!)$($#)"!$"$&*(&")($##$+"&$##(
@r6454
NTTCATTCTGACGAGTTCTAACTTGGCTTCANTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAA
+
3"#@=-,7!$=8#+*"=>2B,91;6<B+9*64(F:$?0H?3#D7C"-G?&49>;@06*32&?/C&*03C5C=7(*'H@E%9(3G*8)4CH;C"/6,7E(A=(H84;!!,?2$6*'4$>('6+(4%7+*%(7E/9F13F+43,=:*!$C;GBG?557AE9766?!A$)#%#5,"8.ED!F$0((*@C91"937-$F/?@:"$F<>!A0$;(<%:(DE&6(@<0"D!$G3<72;#>@'9/G!<+*'C7F=<?HH?G77(@-,'B<&
@r6455
NAANCNTCGTGNNNACTGNCGTCATAAGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCNTTAACTTTTGCCAGACGCGACCANTCAAC
+
$$%$'!)*'")"!#!&"*+'&()%#&'('*+')"+&)%#"!'$!#$%++&""+"+&#'#%$#%&%")$+'$#"%('&+!#"("!&&&%+
@r6456
GAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCC
+
F0>;<&2).E46$4(#23)!7)1<&#0>-D;=3,'F%($#H*D89;/C/*+9
@r6457
TCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGACAGCNTGTTTNTGCGGGAAAGTGTTCGAC
+
-ED,&8F&D!><AH?=0E,+C8@.*-9,&H/@#%C$7?#;BC052);!92%E>@;G;F0#?;=B?7(%G#&$F>#AB.0;D$2=@7+=)?==2F
@r6458
ANTCNCTGCAGNCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCNTGCAGGTTGTGCTGGAT
+
&&!&)'+!"+*+#"()$!*+#&%&)&*!$&")#"%)'!(#!&$(+$!$&&)+(*(#$!$$$+*%'%')$*)('&&"%!&*#&#*('*($((#
@r6459
NGCCCTGGCAGAATTTTCNGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGC
+
$G9@:0><$7$D=G:4=EC<7%&&EAA4""3A@>.,.0%,&'$G#1EHC.B58$=3?G1:<G"1D;GCEG9.5/35(2B>!F&-!0@7/>:G&*32?,"#6<"5#
@r6460
AAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGNACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCAGACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTAATGAGGCATCGTGGCATCTCGTTGAA
+
<%CAGA&D;&1B+C>$.1DHACF$<@(B>7<C%>#?E3243'EB1%(C41HD)-,;>9>'+$E(.78)?B)-8*>++F*,4H-1C;45$+7E>B-,>6"A"E(0)3%6!(8&?:"E'55;##3C--H@".:AEFD#>73EH7?;/ACE1@)?E@-EAC4B9613,8616*1A5360&HAD)13&("?656655(5D."3;&10E66$BB&-A@-+@-<:.CC!E?E*BA1F3/8>!>$B<<)'
@r6461
AAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGC
+
-G-00F'F.;($H0.4!8D@>'D.#29B?%:?AA,H$9,E#*@"'D1%B3C';B
@r6462
CACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCAC
+
C+=#D/$<H)7?3976<;+%D0(CA!G"12*)@0=9HC/?6>5F*7(&?$?C<4>B'>;"(.9G/87(1!G#2=$87CA9D<,+7*5?=9-G6F32<2$B%4)(.)@.D!B5#(;<FG:0>H1&1,0$F@(3=9%D&):4:$?11;.<%?6
@r6463
GCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTG
+
30*95H+!(A>4&H"+,-:E7A=/=C:'-#9C%5&,4'A&*&5.%2>:(@*!2'='H
@r6464
GGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAACATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTA
+
8,0%!(>?=>9/9F""9F/+6;)*$A%&$;'047/5@9=0;)@>+(0%!E'G@8);A!5G:??:26*&!:!,0E!,8F&!#!A.1=!#4,/5B:508!:,.-%H?@B-?F>=ABH-';H.AH:17#*#BA&:)3'73C5.#75<2?=H"<G5&H=H/$EAF/H"G%)8-@5=>8400C("/.<?,*E3?EG40=!F@#'>=CH',!@%E(%>*="A/H47:G=9*=/=@.-C"*?#>%HB==E(E8*9
@r6465
ATTATCCGGNGATGNTGACGGNNCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTNAGCCGGACGCGGGCGCTGCAGCCGTACTCGG
+
0('*6G""+35;F+%5"6-+&>B((<,<G=F-4?4#D.%641@;&C#%,"G,1#0<4(%-6A0=4%14,,?1G2E/4>G8&EG43-&40-D(-)F1-F*%19/'*@37,7>9")E*".'<)+
@r6466
ATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATT
+
GG428698*3%6;$2F86!(=4B73DD1?4?&8E0>%D0-$.(<@7G%EB%/E-6$4E+>(A4#(FF"%@@,FDF#68:5?7@5>/'67$FF;F)42"
@r6467
NGCAAAAATTCTCAAAGTTAGCGTTGNAGAATTTAGCCCTTCAATCGCCAGAGAAATNTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCAC
+
$"4"D/5'7A!(<+<#4!<(1HB:F97+F4;))D%5B#FGF'6G204F252-A@%%E67E5FB6F5)5.4,C4=!?-(#-#*$6?:0:,1>)(:0
@r6468
TCNCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTAAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGCCACCACGGCA
+
'9)!+#*:"F<8E(HH:73"@:666/$>B)8=A;:">9&79!.<@$*G44%39-+)3?<+,0;<+8=!%2@<?ED#03%'H?0*D"03,BC,>66D*&.E50ED+$++5.(4$5!**E&:7"4C.'00"0,/D@H
@r6469
CAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAG
+
F>,/!!5..E)3>6:0,G86DG:48.&&7>E?6!D44*#>#C:16<$15'=/&(DA/>+?0&C%/;HA+2C0=**9E8>>(3,:A$=9A:"5?A#6@4/C$&6/1$00G92?6D?B16?1+B%4((G&.-(
@r6470
CAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCG
+
0:D"=90990%0C@BC<%7$2A<#*B3H8C?%/6#@+B@#()+.7B%)
@r6471
GAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCNATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCNTATACCCANACTCTCTAATCNTG
+
$22<=36@&4H<=%?3*<%B8?9%G2,''=9#"%%;0E<E)=:F/.HH+A)-'+,10?>A@C4-+./)DD3-<#+5')/3)2<>+4C>-$H?!%*"/=>6.;E/!G+E27+5>#.30D"BH16@#E+13C/<B3'FA0*3>E>#AH2@%DH.C9EDG@A4$6B*
@r6472
TANCTNNNANNGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGNAGAAATGCAGGGTGAG
+
!%$$((!!(!%+&"*(+"##$))*#'%$&$!!""!'**''$(#%"$$&*'*!+#'($"$+$&"$#()&%(&%!(%(&%#&)'%#(*+$$#$(!%*%''*$%+#'&'"&%)!!&&+)!)"#$#%""$)%&'"*&'%(""#)#!"*")#()$'+&'#&+()(""*#"%&*$$+#%(*$+*(('$'**$##"+"!'")'#+%*#%'%)
@r6473
ACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTT
+
).>&9)DDFH."9/!7>$%",(>!""F):=)4509$-/+*>/B
@r6474
AGNACNGNGTACNCTNCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAANA
+
&*&&'#%!%!$#%*%&*+)&!*(%!''$!###*#)+'(&#%#&(*%+'!&$#)"'#($!$%++#&"!$+!&%(
@r6475
TTTTTGCGTATTAGCGACCCATNGTCTTTCTGATTTAATAATAGA
+
3#$"8B9D*:>>#+,,*B<&$-4AG8&F0GC;A.G711,#4;H2B
@r6476
ATGCTGCANGGCGGTGATGGCATACGGGCCGTCGTCGTTCTCACGGATACTCNC
+
=3>#3#'A6:46)F.6%%5%($<*3<CE<86'5-$-;+!B*()#"6-7721A#"
@r6477
CANCNNCNNCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGG
+
)&(""")&+")!(!%(%$+'!&$#$#&&(&##("(*&*)%'*!#%($$$"##("%(%&"!"")*$+"%)"+*&&+*+$#(%(!*)(!"
@r6478
CTTTTNNCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTTATAGGCATCACCGAAAATTCAGGNTAATGTGCAATAGGAAGAAAATGATCTATATTT
+
#!%(#%+))%%(***#"%+)%"&!$"*&!)""+"'$((#$%&&#()&%"%$)*$'&&&*"%&$*(!##%(('$!*)$*'+)!#!%&"$'&""+#+(&"&#!&
@r6479
GCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCANGGGCGGTAGACCTCTA
+
+9'<7(H5B4(49.-9.AG+0;8!"D%C9/&0BC@8#;/427?B:F)4:?DD=9?C"049H)CEF+!*9H@H>D$>$)7DHEA4;+(8#8E@8AGD
@r6480
AGTGTGTTACAGNGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGT
+
AF(&2)>-";4>4%=>5>@G8&&16%#?&5E=/235C?G&(%$=?+-5(=(26!2%)89&1C(B?F=0)6E?G"0
@r6481
GTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGT
+
@,H;&HG=#%#C1D9<-CA,30#2"=5;HAHD?;2>=@D/9#C545./5
@r6482
ACCATTGCCCACCACCAGGTTGATNTTGATTCAGAGNTATAAAACGAATGAGTACTGCACTCGCAACGTTGGCTGGGAAGCTGGCTGAACGTG
+
:%67#):<("4!-,G>#,1>?G3"30*(3;'B8@(4>=6HH?:97A1(+*BD+35G=(#>,F1!5BC24F-F$58&/"-$:F014*'),82.2
@r6483
TCTGCAACAGGCTGCCAGCGATCCNATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGAT
+
5$8C&+BC20-DC9G/%/5'=B*A/4)8'"D"#1&.H2>B3B50:96+'0(35E$G!:A,8*89$+0'*
@r6484
CAGGACCGCANTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACANAACACAAGGANGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAANATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATNTTAAATTCTCAAGAAACACGCATCTNATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAAGGAAAATCTTNCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGNACATAAAAGATATTACTATA
+
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
@r6485
CGCCGCCATCAGCGTGTTGNAATCCGCCTGCNGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTA
+
?H<5B7D57BA2%##23?(>G?31*$?+0;*6,29127CH->H@'9>-,6$)$#2)C2FF7?-#4>;)-G(:<"2,%?1&$A
@r6486
TCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAA
+
/GGA/7@")!;'#$G,5GA?&-D"4(1E*2'34$08;HB>+G#5#>:%
@r6487
CGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTT
+
0/)!-G6GA$*"H'1(4()3*B15+2=-+E">E1*.7?E-5<.'H19G2=2;0-:/$.5$9G:"FB9&>+G,!FC:'@'
@r6488
AATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGANTTACAACGATTTGGTCGC
+
C1?>0CA*"E7F+D1=0>(!'C=0?49!""/+<.*/=?6#*E0;@?;E@';,!;.D;90044*E:0?A-&.4*%E#,#;5&D5<?!DG2"2C"$:!*%/1<?1/+9/,9$A&=;!H$@0,29"@2E6+()4"4-6@&)+%8-4<(C/0$(<9/G#37?(&"=E2&3,#&)
@r6489
CAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGG
+
D$@*F?$*"3,<B)&-C*0!C!,+B#%D%2B7&F?D4#<*D7?!E7;C:%'&)(G8,1>6F<;,+%BG0+1D*"+$@G;H
@r6490
NTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGAC
+
&5/.*!A2=@8*2H0F$E&C2?4A>2><?F'#(C6EC!AHGD4%"7>@0&*"0#+>7F6.+%,8G64/7CF,@G!@2=/@GC".@#60*8+4BA7@1<.7<DGB%?*161=.*A&B9
@r6491
CCNACANAACCAATTTTAACATTTCCGATANCGCATTTTTCACCATGCTCATCAANGACAGTAAGATAAAACATTNTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGNATGCCTTATTTTTTTC
+
&(!&)'#%+!*%'&#+"**(%!"$(&!$$"('"%('##&!)*$$+++(#$!!$%('!!$"!'#+"'$#$"&*&#(*%$)*%*'#$$*+&**()!*+#"#((+'$'#)&#+)&&$"#&)+%()##$+%%&"$
@r6492
GTTTACGGCTTGTTGGGCTNGTTTAATCCAGNAACTGNGGGGCTTTAAGGCGAGTTTTCGACTCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTT
+
,0%4+A--B!6'92*2/7121827%?%@EEF0CH#(>2,62+7-B9D,(<":&3%.-$*->8CE)7;@'>6&@*9:.E=.7$(1F+<2@(H'=4?1E/GAG)5!F)=9BC*@+;-7E;"G%/=8206)-=96D?G.97-5G&=)&.EH8B;6
@r6493
CCCGCGCATTACCCANCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGANTCTGGCCTGCGGATTT
+
+'(+$+!#&*"+!'+)!!!)+((!$+$+(&%'($!+"%'!#$*#&!(++**+$"$&*"*%!(!*'##)
@r6494
ATCGCCGGTGGTCACCCAGTTTTTCGGGTAACNGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCNTCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCC
+
,"D7+!&$?A6*%06:B0FDB57#H9'$@&9$:56-(6;AA/!83C1("DC/+4<";57.?H4@"E;1B3#@5%(39C<@#F,?4"?A*+E1#-'8A3@11?#%!)
@r6495
GGCAGGTCTTCTGGNTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAANATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTTCCGCGATGAAANGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAA
+
D-F+";A($-5>HAA$H/734'#B!>;9*+,7??"6AC=A6/0*D*"?,?:&F043>H0$:@D$'%16.9-"%'C7+!E/=1#+*-B61>039'2A507'CE9'E<$G'>2AF:"@?,%/E71GG:GH6CE"=D/A%H$;B9G:49H+$8:E;#')67>0!$)B$E:$97*'@D):&.?E7A.915+
@r6496
NCGTACTCCACATCCATGCTGTAACNCCCNGCTTCATCCGGATTCTCTGAGCCCACCG
+
!:00@C4$*4AE/B/ACAA8A5;!;)#9B9.5$9!?>B3CFD818F)@>B53%7./97
@r6497
CGGCGNTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCNGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGA
+
*24+0E1"7/*7:3E8C+4+.>$"+?=#G<'6$4?<2H!&'+3*6$3/$@3F;5>5)<4#?7@7+C@<8A84?E>&B.0<3&C$&%A28=E.2%4/6'=;&5*812'.5!&5A;331A0E<H1
@r6498
GAGATAGCTGAAGAGATGGCACATTGCTACGCAAGAAAGAAAAGTGATATACTGNNATGTTTTAAA
+
?EE&C&+%!%:G1-%,8H<*@3+F7/:&27(<-;A=A'=#'7<4<;#$%H1*4;&/>(*9<GA2%E
@r6499
ACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACNCCCCTCNCAGCCGGG
+
A34C0)6@+6&49B/+&5B)7;@=)*4=/27'+)&;/#$A::DF+!:&84"5-%FAH+G*8;2C$!F-07=<34-G!79:D,-.&(%A.,9$-EB.1@>.B3.!)+2H0%'83+<A/
@r6500
GCATCATCGCTCGCCCGACCGACGNCCTCCACGAATGCCGATTT
+
1>"%;H9FFB2/91D#(65B63)5G*(2=G"!/)=D1?%+2CBH
@r6501
TCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGC
+
(+*#%&"!'%*+($'("&++(*&%"(#%(++*)(!$(%$$&$))')!$$+*+#$&(!%&
@r6502
GCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGAT
+
4>D2!ABG$)C;>D?2>1$3.FF+C'CD87C6FA),A2(HA0G*7%.88:9E>1=B@BB<?$##:$9<09@=C#!.D&%+87<68C:%:<(34,"62$/F-/9G(+.3.HF7GB-30<7,D!11G')+<&"HF
@r6503
CTGGCGCACATCGCCTGGCGTGCGCCAGAGTCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCATTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAA
+
7,8;'3D:7"$H/8@F//2&>-2A(@7?D'.=.7.:086(777B&0;/D)D6<0,4+E2<>=1C'&,%@1$2>@E<.C"/A4;A-<@HBD;%69(E9EC=4'6//($B@=-?24>&4'?"A<*1C0$!H8"6,0.&,+*(>+#57'$'-1G+/>82F<.<A<EEG&"HH!&#($89E/E3?$/(?43#E)D)&6<A9>,@A/18"G2;01B8-1.#C-6A<!64*'G92/(83EF<()(<2<'G6?H<&=<)4?2B+$10:-GDE5D@)
@r6504
GTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCANCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTNCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGG
+
/@%'3!38#:%77'8,8D%=$=D3>H43-2;%&==<%,3)6$7.6*'3"64+B8E;1G(C?,;!C.&D"91:?C#0:!)D/-F4!>;<2,HA<-G@0D95E3A#%1*!/9%/B35BA!8,>6&<!%@B3'E")+46"C70:C?E%8D8EF@#5A&464(2H75(3'G>+>$%D>4$3C$A?.8(4<!-1:*88C,6,3A:;55G,,A3$3&0$-,-D4B+$!C&80D
@r6505
CTGNAACACGTTAGCAGCATGATTGCCACGGATGGCCACATATTAACGGCATGATATTGACTTATCGCCACAGGCGGTTAAGGTGGTAATGGATNAAACGAACAGAAAAGC
+
""%&#+$"#$)%*"'$*!($)**""%"!!"$*!)+*+!'!'()(+))$+"+*"(#&"++*"&+"$$'*"*)'+*$!"!'")+)+%##)*%!)$("!#&#%+"+!+)&#(($
@r6506
CAGCGGAACTTATGAATCGTCCCCTTCGGGCAGACCAGNCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCGGCGCCACA
+
<G05*.1631C9(;D/%)+3>9?E"?@:<5F)4-*/8$4?%<?%890#:=#*(=8#48?HF%01@:%1'&!@$*#>;'4?B,&"@317.5A5),!0-=03/8@+$,548(#:5:*700-9>2*&G=78:
@r6507
GCAACGCGGTTGGCCCCCAATGGCCATTGCGGCGGNACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCA
+
+*'!%!!"*'#')!#+$&#$(++#!)%(("#(#'#$#*#&*(&&&&"%*$!(((($+*"&''(%&))"*'"%&*&+
@r6508
GTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCG
+
3D0B:8!G7F*?B,/)>>D*77.F66C1@9$-77AE1=:,@?/06?4/F!:5=(?)B'6E9D9:(CG+?@*:=D10B$!('>)0'.=@"4E>DE&1)8>=/G@"./3(+038&0<6A/(("<(=5:$929=2F2=E/@+&0">D#,E5B'7-;"(/5..+-E?50#@.?0<1C3;G(9(
@r6509
CATGTTCGATTTCAATTTCTATTGATGCTATCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAGAAATCGCCCTCACA
+
2B";,B#"#A'=;B38=8GC$3'):)C;9859'8C-4=<0.*9!,$#!9.'+G<=>&C:(2A23)/D%D,:314:D&)1!@@?@$E5D@(<>!.,);69C"G;!B9'
@r6510
AAACACAAGCCTNTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGC
+
G;8(2)474.%B08/"1:9D7A7%8#D30D;*85D9A=D.7B-&/4-D3%=D)"*8HF,+/"?/'$":!#25.1&:0(?5@$B*FA'+5E-F,,*&<"7'6<1
@r6511
NAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCNGAAAAACATGACCTGTTGGNCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCT
+
"+;B492$@&5<223(?=81/.(@3F#.B-%68"CD)1?2B98+:<C?;@5178(H9@)8<?.G1@66+:456/<80()+,)6B1=8+E**05!;7C0$&&!@-5#'GC)%8B-@.:G<HH8,')6>2
@r6512
CGCTAGAACATATTACGATGACATGCTTTTCATCACGTGAAAAATGTC
+
("+#*(&'!(!""%%'(#$$"#+)&)+#*+$*#&&)('+)!+$("+)!
@r6513
ACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAA
+
(/6++D8;G>D)/8C#B*3B?!A$81=0G,E.@<AA<"F,&E%4?8
@r6514
TCTCTTTCATATTCCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCNGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCAT
+
>*A:98!D%6D'$EA+,'?F/3E%.DB=6AG>>%4<'=<72F2!=H<$<B=35B6."?-;=F%E,7'G%;8BC1G!90)2:4HDFA'*;@:6)CFB311C4+>1C>&<:<C.>G71-F-1-+798E.?:F$5(?:@&*4H#F!39"50>4(:5$%'>/B-+#@!3
@r6515
CGGACAACTGCTGCAGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCA
+
DG&BA<%%%EB#*C,E@0G,+#CGD#=&)9#5*'4>>%&@!#687.FE37-&D+&5E/38"-G#?+$/2E=&%+
@r6516
CGCCAACGACATCTACTAANCTNGTGATAGTAAATAAAACAATTGCATGTCCAGANCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTNATTACGTCTTAACTCTTCATATTTAGAAATGAGGC
+
+"%#!*#"(()!+$%!#)**!*+!!$%%$*!$$&()*$('(')(##+()%&!%"&'+"&#!&)+"#''+'&'!%#)!'$)*+%$%$*"'($%$"()$&)%*$"*($&"%*)'(*!'&)!((($#!&%++%)**'*'(+)(+)*""%&"'&!)$''"+&))''!))%&+""#
@r6517
GCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACT
+
C...G7+FD<;:6-CD=:*>;C6$H@B6/D/!$553.,G.=7A'?.G/E;<9E6G-D&#!'?)6<=B%;50B>,1D%8@:>:;2"%9$
@r6518
CCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAAT
+
4GG30!2=(2&,50%D&'58+4A/"'!G">)9*<G$!63&'!
@r6519
GAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAAC
+
**+""$)!!"%$(&*!*%'(%"$)!*+%$'$$%*($%+%#&%#*)(%#!'#(()"%+)'%)))+%&")(*(!!%'"&%$($*
@r6520
CATTCTTTCAGTATTGGTTCACACGGACGCACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAANAACATTGCATTTAACTATATTGTNAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATANAAAT
+
D!1.*$B02.)'/4(2<3"+4'><'.%0!DFD416#D=<?G2)E&C;B36(CE99<HE$)CCC+.*!94(G8FFC;-)6G=!618C=?,:HG2E"#=,%;$$>B*@($$@'74!$E&>/6;8,A,1;9A44"*-7$E:0;"(,C&=H"!,=
@r6521
AGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATGCACCGGACCTTCAATCGGCCCTTCGCTGATGGCNTCGATCACACTCAGCGACTGCGTGGACTTCAGGTT
+
')'2+/1/"5$0?:?C)EH'.)DH2)<%;CH.+A'-$.6/'#&(C7.3D>6&1H5=0A#$5F0C-$/D3H2HG:H%;4E@)(#">5DD,*(?H(85./617C7F,BC$.=,*C.02@
@r6522
GCGTTACTGGGATGATCGTGAAAACGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACA
+
1+;D"*,**$5"D7DB80F5-$&)8(:@7$-@H+6@?.B!%0B/+B!@@@0F=(:-$7</$>7D?&!-.($H404?EH
@r6523
GCGGCGCAGAAAATGTTGTTAAAACAGAANCCCAGCAAACATTCGTAAATGGATTGCTCGNTTTTATT
+
"+*$"&(#!&#)**!*%!&#!*$"("%*+"))#'"#'!(&'%(&+''*(#"!#(%))+'"$$#%&$("
@r6524
NCCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTAAAAGACTGGATGAAAACGAAAGGGGATACG
+
%+(*'+!!!*#($')&)')##)$')#)+'&#"&"%&+')+$++!$!$&%+$!')*+"%#+)%&+%#)&$"!&$##%'))""'!)'!%!+*"&"&*!$
@r6525
CCAACNNCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTNTATTTTGCATCGAGCGCAGC
+
!))$(%##+()*))&"#'*)+$$&'$*+!+*%++&))#++)&'#)+!**#)#&")%+&('$!*#!))($(#!%%
@r6526
AATGATTTTCTCTGTGCCATGACGGAGGATGANGCCCGCCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTAC
+
35/5%/)B=,)C'()$8:*+#-/"A!C?!A0%0(4C*A.),@00D7>(EF:@@9@31F>$$A$-G7-*2=")63!>20H9FF?:<*:A="3#D8/&)F4,ED'HG#??F3B3E
@r6527
TATTACCGATTCCGGCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCANAGAGGTCTGCAAAATGCAATCCCGANACAGTTCGCAGGTAA
+
%#*&'+*!*")*)''*'%"(#+!##*"*(#)(#&!&(!$*&&'(!'#$%$*$'!(+&%!))("!#%'#(#)'&(**$)%*'$#(")$)&!+(&)&$#+!%&%")!(
@r6528
TTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGG
+
CGE<'+17'%!.%-.=*5GD1B5)&&51,:1A#G1:F.";&5/&E($
@r6529
NTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTG
+
!(H72-7(B,,48EA62*=;"+0<65.8<F7=:H2E=,&&74.HDG924$9H"H=(G&*8>:C&D4A1.4%',(=
@r6530
GATAAATCTTTAAGTCTTCTTTCCCANGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGT
+
,D3973766A7=7<6(4'?-=*2@2;;251=A;HGC+F.H*D,!+,".*?*1$:/$**87900@9:D)")(&0F5'%G>>698BA9C**$?:A5
@r6531
NATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCNTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGNTGA
+
"2?"%)"9;C=<B(<9G/06<:*0$&;H>FE8+C9,;1CB3:+/>%'!5-0B=-@38C:)%$<C%5B*B:=$@%=E$9A"4+F.%B6C6+EA@83D?D!49AC&743?4>.E$"$='>$C,#6B2@2B#"'E2";%ED,;23E"A;B&;*H<'190>/)$;A,<B8&32!/:5=-!@B*90@D<"))=./F."-%$5+'#7&*>@=B#87-.86GEF$"A(*7/<)6
@r6532
TCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGA
+
9)H!&H46@).@(7.1$AB.H!BF7.*9D2#'+6202E(-?GA&>.'B)2<51'>)E6C.*&DE,1)+(,!C#0A<B/#)%55F+3=7""B$07')-H)*?)':F?:*0.B(#2FEGD#(4)A+4?>9>6!&94E@:1@<?
@r6533
GACTGNNTCNCCGNTNTNNCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAA
+
&!'$&(('&&$')"('*$!')+)*&"))+)(#*"+&'+#&!!*&&$%+*!""+"+)(
@r6534
GCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACGGTTCCGGATCCNGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTNGAAATTGCAACGAAG
+
&%(7(2"10"EC'3?)<79<"9E8C;A=8B;-=>?&.@86'7@::$6,-:"B7H1>6D/829;2*0D(:&,9'6A>'(E=,1E.%-0<'&<)>!?@3'6(9FAH;4+!>DAHEB:F"F'B?*12%38+8<2,<$1$.$.&C*6
@r6535
GTCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAAT
+
$=.G51H*;>>!)D$79:*H-0*$2###9.18A'9A1:F&<H<G9
@r6536
TGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGNTGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACANNCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAANCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACTTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCG
+
-!.H.'5F*)@D2&D26DE*9.H-)-1#,.5,!0D*GE).78+%A29<:'!B0%G%39&E:@'8=4<?#"A&)(/4C8</$+).#'68-EB6E!FB7+6"G,B4CGD1:)'">6+E(@0/@D4E-D0<0*3A<B.)"@A>6-?;F%$7A-A;23"E'>E.=14,45";,.6@E#>2*/C2"<*-5%/;D*H>4CE'AD/1A:1?8.%#:7*73&)C?*7!G.5<5%?.*;6,,>"72D:$%38%E2/&F@.&.%4EA2@@#<4/)$
@r6537
GGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAANAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGNCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCC
+
6(!0!,78:!>2/>F:"9,!C1(3G'5;%;@DGC&H7C>(+6='&:G*DF%CB0.G&%-E9-;37C5&>"<4!79/@0H3<#5D),>&=5'4<(7<=G9$3#:611-&-D+%$D..CGE10BG,G'G<6F3*E0>E%E3+7.6>:)%.4B7-&<6"H0(-H837*C!:70=>&;$HHA*#'4!!4!B"?9",<B>E1B'BA6/:2(3?+61>
@r6538
GAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTNACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTT
+
9?1B;E36'-@E03&C27AD4%"=AG"/1643.6HA@>$C"0"(;:';8582:G1B9&./&.C=7":<2+>;4';@7=6%)<,5BB*3,73/!F=:8B#6!7F7C-:DAH17@<%&90&=8-E*@9.2!F+&>G1.!2@'4=?,EA:#@;"1.4)#944;';.
@r6539
TTACNNTNNGTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGANACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGNATATTTCT
+
$'%#!"!#$!(+'$$!$('(!'#(("$)#*!*%(!!**'"&&"$%)'$)")%"+#&'+%*"*$$&&%)!#)*&!'$$"$+(*%&*$'"!()+&#%(*"'(*''")%'+#)#)&*&&)'&"$%)*(!*&!+!$'+#)*($*(+'%'*&)#('$'*+))+)!*!+(
@r6540
ACTTTTCATTCTTGCNTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATG
+
C@C4*C2FC'C9':7>-;(,6?9*4(%B/,<%4D#&G!><?9!?,1(+2;D5037$<1E'173<:/!!(-D<D!?5$2H*0
@r6541
CGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAG
+
1C$$=$!'6A527>,%E/7/A:*/,'%,7##@G:F-&,.,2'B%"2!.$FD2)-8G#89A,7C3;F%7>-H=,C.7&;A#-G4=4:G;<:/C44:,'7E40"8##A?-?:HDC'*0D*2>A>16-,(.=D"2!ECF<2/%@
@r6542
CCACANNNTCCAGNANCNCCATNGAGNTACTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCCCGNTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTNCTGAGAGGCGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTG
+
&$%%#!%$*'$))%'(%!%#%(!$!$$$"+$$''$(+'(*')#($"#'#!%$$%'""'&#&&)++*%&!#'+"'("%)*$#&(+!""'!%(+!%'%"'&&'#$)#&('!!**)&($+#"'!#&(()*&(#)'&*#'!$(!$&%($"(&""*#$('&#$%*$+!!%%$**((*%%'!((""(&')$+&+"'!!$)&)'%&&)***&!!!)$!'#$#&"###'!%$#"'$$("#((#$"#&)"%+"$$$%+&"$"+$)(*"&+$"!!&+%+(()%%*!%%#$*)+"(*(+*"""
@r6543
NGGGTANANNGNTTATGACGTNNNNNCGNCAANAGNNTCCCNNNTTANCCTNGCCACCNNNNCNANTATNGGCCNNNNCGTNTNG
+
!"$!!$""#$"#"##$"$"$$#$!"#!!"#!""$!!!""$#!$"#$$!#$"""$"""!!!$###!"!##"#"#$!!!!!"$##"#
@r6544
NCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTATTGCGTGAATAGCGTTNTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTT
+
'@AC<B9HG>%/:0,@%+9>@FD4D:=)/<?4:%)+>0C8*&#*5/G?15.#0('7A3=:F1@3GF?G?D<H)=G>@=:E><7';?G<7E>1*129A$>+/1CH"@#'A%48>63!.8-+GB$)0*F5B248;'!9<0>6$84AF18A(,#1?"80
@r6545
GGCATTCNTCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTAGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGNTTCTTTTGGGANTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCANATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAA
+
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
@r6546
CGGATGACCCCTCNAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGNTGCCCGTTGTATC
+
,/(781D">*2G03<9E<%F4=F3>8C$7,</>22.CBA-F&6-#53'7!9E0,6?B=1)5=<$3F06**H;C3*7!3)H)"6FF)D+
@r6547
ACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAG
+
+>?C(/EAEA<'$@2;E$B("&A87F"%*G!=7(*6,7;#%#=4-!4(<DH/HB<1.FG43+&&4+.)0'AC=
@r6548
AATNGTGGGNGCCGTCNGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACANCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATA
+
5'F"!!0+26E*;@2EA;F'/8HD"#G&?DCC3=BD:>!,9+0(;#0.H#67871+GHGG1>9!")&>*))@%?7.0!;#C';5)%>5"29H-%C4:=",:E)H9/$'?%6&
@r6549
CATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAG
+
&/>:&%(;H3#;7$&)=':6*%F@)#-$#/2?1FF"'!-@6.A+2B:@)@@2,;E-@)D*)A1!F(E.<0010'!H37E&4',=F9ED$654#4(9,45D,>5DH#+:,4*=%-0?@"+EB'<84*'8,B?5%B0=1%3D'8E"&**.3&2,/G,=%8C:%G2"0)$.FD+B+AB!/E.#)"67A"2'FB=@D%)+(8+"!40)8"42:,4(H/7(4;&;4+6??CE*
@r6550
CGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGT
+
99!GDH;H)A5A%G/(,"D"4G<FE+2">=<EEE%"E,A:7!H&3*9'.DG
@r6551
TTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACC
+
41A>-;2&D9E:F=@=C*:4&"@9-"-0@CE/,H*.&A$D$
@r6552
CAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATAT
+
4G#/$F<3?',8F(?2/3/!D));-@;?(9?;/1'+!514)'%1#FC?*$>1!ED4@08%HC+<<F848>1%!&(+"<=)$?--1()D,FB&<@$)H74
@r6553
GCGNAAACTTGACCTTTCTCTCCCANATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACNGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTNTATTTTTTG
+
-/B/CD8<A/B+(A*5<,5,(4-:!7.9$+&$A9$03";6'@9=;=A9$!6$+%6A:7,,,48>6*E?37H(60=+4A6&4@'9H?#0@A8*C2H,658FF<'=')/0:E<E89&1(5
@r6554
GGNNTGTNCTTTANTCGANATTACGACAAAGAAATTCTGGCTAAAGCCTTGCCCATAAAGCAGACGAACTTCCGTTAATCATCGAACTGGTGAGCAA
+
'"%!!&*&&'%*$%$*)###$+"()&&*+*(&)#+(!)$+*"$%!'&#&)"*$'('*("')((()%%"')*"##!"&&&#"($$)"$('##!(#))!
@r6555
NCTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGA
+
'.E'9<45B31D:E($--!8+C?>.A1B9/A:.-+0(/;#6('390<::"94''$787;,GE0-*B79.%%+%)0+*/;
@r6556
ANCAACAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCATTCCATCCGAGATGAACCATGAGAACGTCGTTGAC
+
$!*%$)+'!&#)&&*')+*%()(*!*"#"!&()'&(#"!"*$"+*+!"+(!*!'!&)&)!$(#'"*'&+!#(&*$(%!+&*((")*+'))%(&%($)'+'*!"%('&!&%#(**&+!$&*%$&*$($#%+!%&''
@r6557
ATGACTTCCCTCTTCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAANACCNGGTTCGTGCTCNTCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGACGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAA
+
C'-7@5+AA&"B*)=$">D=D<DB!)ADA7!*&<5#G=9A@3-&,%CA%$9298=1!5D=)8-;8&C<>=C'=05@>0'59;2E1B+5-.B<*."/-*/>>%43,"E@F#8B1C>&90<@H#BAA-8&68D)'-B"')CB64B&E?H$;.(;%.#=7''E+5*7,;CG9A;G,70!D?7?256F&00.H&:93H+@F13@??*<.4''+-E>6,-&(,45(@+4,C'H?>>#&(6?F-3@C,3?E9-$@-8.,E>'E#C5'=;68@E=6G.$);2:*0:)1/53A'".%)=0+0B267!70F
@r6558
GTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTTCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGA
+
+!'%)##+##'%!++*('#!'"(*)+'!&')((&()$#%)("+$&%'*"'&&'())#!"$!$&$"$!&"*$&!'#($#$$%#&'
@r6559
CACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCA
+
&),D*H*>.FF,F,B.-,2D'/6-29E+.>!45",D%?BC"G:B+
@r6560
GATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATA
+
546("8F"F$+F8'@/19'90C@*&$';D=80@"%'BBA8,3C+;$*'/0)H#,96:1:*'D2%/@:<,-"(&/'+H,*$+$?&>C0=&'+&*23!1<=:)?*$+14'2*&@(""3)/>'$/F$*/G87"$
@r6561
NAACCTCCACGCTGACCGGATTGCCACTNCGGTCAAGCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGANTTCACGGTCGAGCGTCAGCGTCCGGGTCT
+
$(#++')!*+!#)$%**%!$$!&(%(%!)%%'&%%+"+(($$+&"(*&+("%(*)'&%+!&)%(*($+%(**$'!'"&**'!+$!!%''%"$'$&&+(+%%)"%)
@r6562
CCAGGGACGAAANTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTA
+
8F""&C2,%8&&9.D,&0*-&%#E"-3G0D()06,'=6>&'B6A85;>1,>H"B(060*(
@r6563
AACACTGTGTTACCTGGCTAATCAGAANTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCNACTGCCGGAGC
+
%F$+4*5$H#.55'6;5&0-G,/32550$/+>,6B8=!E2=!<?6&1.10E';;BG&D%F26D@8$03-DB!CF+7+D/H);B
@r6564
TTTTAACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGNTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAA
+
8%$H$%;<401$0G,@5#&'BE<82<-?4,83-)?(HA-;:?1AC8>00/1440-%8.7F367"($0)$3!F/A1H&<*$F8F?))45*8,#83?6**F/7@.&*E?/B:.:GF2GD84(2H*8<+,DF*2/@71,&<*:#%HH29H%%HD>@'4&"6(<8*366G%@"*8D.;8GA/$:3$=@&H#(1+)B8GA:-6*/E8+!$:6@23?&4-@E;@EG"/H8*763G**""8CB"C-"6)>47&H"64D
@r6565
TTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAANGGAATAGNCNTTCCAACCATCTGCTCGTAGGCATGCCTTATTTTTTTCNACTGCAGG
+
)7B:$C0D.&*9A"#@:>.D=7(?:+<:C?A9+G>*E010G0680CAH'H?D#-D9A6&B'D9'<DG+?57E)"-3!44"1H$)14F4&%:A4%;*4>DHEF
@r6566
TNCGANACAGCNGNTNAAACTTAAATTTCTGCTCATTTGCCGCCAGCCGTTGGGCGGTTGTGTACATCGACATAAAANAATCCCGTAAAAA
+
!%$#%$&&&''!&!#)+%##+$(#$+%+'#*'&$$*)"$(*()+(#+"%%+"!)&$*+('$("(#"*$(+"!!%)&*')*!#)*''$&+'(
@r6567
TCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAGTGAAGTGGTGTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAA
+
+)*''))"#)%#)%&"%'%!"!&**&"'!#*$&#%('("$'%**"&&)$&(%!$'#'&*!*(!%"!+%)*)(#&+'+**"('"&#*!+()(+$(&(!$+$%*'*"&!
@r6568
CTTATAAAAAAGCATTGCTTATCANTTTGTTGCAACGAACAGGTCACTATCAGTCAAAA
+
!*#+$$"$!)&'"($$*!%*()+""++#"'#+$!++##+)#!$'+"'$((*)*(&+!#*
@r6569
CGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACA
+
(H32*,/90<),";<1F(+<7E2*2+B0>)=A'6<#-6+,B!:4D9($/0)%67+92@>8<>>",C<D-5<DB%(A+4.)1E'6#')+"6*#71<).F)5$&21
@r6570
TTCNGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACCTGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTC
+
#(4>*H-?5A6-73.H(<)&!EG9CF>&$H>:E%0E#*7+C+,>=)4,';3,3%*)+''(H=0B08BC>?80H2&/9D3/<7&H8154$<C2;469(CA9---)03=3'>9<2!H,?9"4.+$C330E3?%%!-(%@1%D//.7*?;
@r6571
CTNCAACAGCNGNNNAGGATGTAGANGGNNGNCAGCNANTTGG
+
"$#$!$##""!$$!"$$"#!$!#!$$$!"!###!#$"$"""#"
@r6572
ATGTNATCGGTGCGGTGAATGCAAAGAAGATAACCGCTNCCGACNAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGNGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTNCAACG
+
"+"+##$!)+%+(!'!*&+"+!($*%((""($(&("(+)$%*')*'"!$$!($"(%)$)!(++#%(%%$&*'"*#)#!+%"&#+#+#)(()+!(*%(!*%$*$'&(!%*#)+*+("(%'('#$!#)"*)!!')+)"!%)""*)&'!'%"&)!!*()&&#!%!$!)(($)!+"($)*(#+($#&$'&"%&&'$)#&
@r6573
ATTGGGTACTGTGGGTTTAGTGGTNGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTTATCACNCCCATGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGNGAATTAACATTCCGTNAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCGT
+
B?.9'-<6"=F2B#C!7#@7;#.#+#)G%2)<41DB11/*531217?#;,($60(&!1.F(?=F+5D%8*4"+H@68$6)5H<(@($%39957&(5(716%)6-)DF+>B(CCE",/G025C(<&;0%?-??:E%9#-#<98F%9B5DBE.73*+"147/G(A&@E??!-$9%5<)B+"";<BH8"<"D*)-=/75/8&G<)$$B/<*+*H1*:.0A0A&HAE.&;CA$>7'.@($"-(*!)+4:9#;*F)"!/A=1+0!AD*:+5>@
@r6574
AGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGA
+
A4=9(+-D-3%=?9,9*'&AD%2&5-*">%"(->0BE11*D-''>C3'3;;56C'<B
@r6575
CCNGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGG
+
?:F=72!+-)->6F:&H.8;A9';2*!4:F)&1*6/H9=::%?&H>'H6H&1$=:65$::;1&-G!0@)+!5".6HA2(,$??6<>
@r6576
ACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTG
+
;+$H)(#+>5#A1#G:"&76/>"!E1!B(+7;-(&$<@*"A)H';6(B&,3!<+B';8&,4."@/0D<E>A&-;=F.@7AG)7*+-653*2$?4"5(*'8C&407&5=.+83,;91=GB(:8-(**.0@>*#0>
@r6577
GTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTAGCTGTCAGAGGCTTGTGTTTGTGTCCTGANAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGNCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACT
+
$'8)!1F5+49019><H$/2G2"@G*(HG%>/$!)CA+AD#D5>E'*!2&.H$#</E(9B=%A6>;;,'.3)F*!#/*-!'!%GF*AH*<':E"0;B".#)D21-18&:32:77H.>$5;-E&%C/@C6(:35E8&!7212)-GF-?#$!0E.H!<4A!><;F<%%85>;9>>.CB>)7!B:'G'#G)?*7086$2B,/B3*#2BD5&-$90&96?!8)<(>$"7:!2"/AA0)
@r6578
ATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTNAGAGCATTCAGA
+
/9><D!2E5>,<9/?/&.>,(9:G,$)$/<9&9G2G%D.&2%%+-"G.B!,<@<.<'71516)?,;;F&DE:82?7C3",>7H0!1+1%8/(GG929E$D#)5:A!F53H&2C>0"
@r6579
TACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTNTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTC
+
G=:>2*$@>01+%$+.G)%?)C@13&F#@*4,2F?B;2#8-E)@=H'E!F*"/9;)(;8,DC.3$""9<$0D9-?;!>F'262<.9A(A9*0'%9?-364'@
@r6580
CCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCGCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGG
+
$F;11H+C#5D&?.92737-G.!E<)G4B6'B%@?C"/)@7-=:*C+*D)7DB13=:HD%6?HH?:1E;+0"?GDF!H27$E60<B'H5#F)H@+'"!B))$%5G?C@0G/2!14!..5-H?A@+@CE2)+3#"E%1@=2')@$01C*9=
@r6581
CTTGACATANCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAAT
+
8!DD#!<91&FD0+!!A/7G2+,@8$?*2C=$*D!<,"9+B#B?-&9#,>14'5<2&67'4!&5,C5D?
@r6582
CTCCCAGCCGGACCGGCGCTGCGGGTAATACNCGGCAATTACACCAANCCAGCCGGTCAGCCTTTNCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGAAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGT
+
+-4).+)D$90'"?23'&0)G)2--='<4#?7D%,B@DG6.DF?"A(=02&GE9%G5!:+/E&625HEAA-)9.*C;D#(1=,3G>1D6C'@!2'5G&B#1=$=+B';@@>9C)*0H'$F33HB7=49,G(05/$GF<F'>+G#)+'3)"B1;B*'#$%'3?C7DG3<8'529!1E>CHB*$H&G=-+D5-:GH@C-.#=#)#'%CA3$+?)02D:>8C9B.-'
@r6583
ATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTG
+
@G.@0"&4)%B'HD=D-8+#@$%=2*7-C7-5-1,!;6B<C.7546
@r6584
TTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCA
+
>>8A-'/%&H4&78$&*2'4+1(,04"H$!<3@<:$,1!!AF41(-C3G/'E2+D''H$"!DB8GH$*74A656(CG7,.03;0?GHBF)/+-4C,,#&44,%G7A8>/+47)$B7,8&@-B7'HB=*(<$,D7ED8=.=>D;D:=E1G@"E("1+?>%3;
@r6585
GATTATTTGACGTGGTTTGATGGCCTNCACGCACGTTTTGATATGTAGATGATAATCAT
+
9'#7577-F8-);)90##"0/&6?//H@>F-3"'F9.0<9508*@#G)07+3(H&>E,=
@r6586
NTGTNNCNNACGTCATCCGGAAGATCGCTGTAGGGGTNGCCATCCACCTTATGGCTGCCGCTGTACATCAGCGTGATTTCCACACCCTCTTTCNCCAGCGCAGCACCG
+
!%!&##)%#(++$%)*!%!#$)!!#"'+#+'%$'%$$+*&#%))%%&$+%%$)&$((&!'(#!'"(+)$&$+!'#(!!$$+""(&+#'#*+)!%)))()'')!!("*'
@r6587
TGCTTATGCTTGCCGACATGGCACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATT
+
-);?>6B/,A67%'!F704:(EE=/+..*1:9('&B+EA7A?DE'B6/#G8.5(<@7(((:1%*>02
@r6588
CTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGT
+
=52!44BE/FG2*8#;=#"3F%#ED%D;?&48!B)-!4ADD3;%.@>":C:0F9)2:"%D7F0#5G(4<4AF+.#+7->>3)&$?);/>22*A*C3E%C(!11@),CF=>*A#5691H=9,(@$HC1#+.2623'GE
@r6589
TCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGGTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCT
+
GA?&404*/70$-*1D9G/(<D<HBG3467.<$+#.#+'+8B8)29<3$*0&@C>G;34;%%EC0A=%<<C*+#/*77'C/%-,*
@r6590
AATAATCAACGTAAGGCGTTCCTCGATATGCTGGNGTGGTCGGAGGGAACTGATAACGGACGTCANAAAACCAGAAATCATGGTTATG
+
H!6G)8;H!1%'D%2">D.0(75B<=)</<9?.6$7?%232*$G6*!/D''7HB'$*>D&A7@83+%D+38:3G1"-2"+A#6=4?1+
@r6591
ATTAACCGTGGNGAGGCGATCCCTGAACCAGTAAAACAACTTC
+
+:+?+==8:/3#*"D,6AD*(2;G8#/<38G2$&G/-@=#=?E
@r6592
ATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAA
+
BF.)<+C2(=/53<6(C8?+#%9+:@B9+4!8-="3?9:./AC:F$G*(B>G3?C#4?:*#;E)+.F5F3
@r6593
ATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGA
+
E("5G-?GD$?(9@7%38'D2/=<ECF((5*(>!CH"E::0:E)/52
@r6594
GGCNNANGANNTCGCNGACGNNNAGAGANANNGTCCTNNANNNAGTGCNNNNGNATTTNANNNTNGAANATNCC
+
#"$###"#!!""$"!#$#!$"$"""$"$"$""##!$!!"#$#!"!$!$"!!!""#!"$"$#$$$!#"$"$#!"$
@r6595
ATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGT
+
,608DA9+"?<F+=E'D=;"),5/-/96G25%!7H,5F5'-52"5EG!/E
@r6596
CGNTGGCGGCGTGACACNATTCACCGTGCCACTCTGTTCGCCGTCAANGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGC
+
*'+(#(+!*!*!!"%&"'#%++)*$(($)*!!$#()!('#$%*%)%#!%!"&*%#*%!"(''!"%(%%+"+"($$)"(%++"'"&)+"!"*&!+'""'"+#'"$)"")&()##(!'
@r6597
ATGGTGTATCCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCGCAACGTGCGNGGAGGNCATCAAACCACGTCAAATAATCAATTAT
+
54@-G+/?D/3D0%-=D.6#!H%=2.$"(H=>@.H/(CCBG74.BA25D(,D;71?/F#&,.)0+2+=,@A:?::B:490=/-#7/'/74$316?,&@,5FE7'##8*B7>5152&4&*"
@r6598
NANCGANAANNNTTCNGNCNAAACCAATGGTGTCCCNTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTG
+
#(!&&*"(')!!'%*$)!!%*+#'&$)+%'+&(#$+*(!*$$"$($&%)"%"*$%%%)$)()(#!*(&+%*'))'!)$%#'&)!'#)(*($&%#'$$+%"$*%")&#'
@r6599
CACTNTTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGT
+
&)+#''*($!+'*%#$#&+"!(#'")""*%**$"()#+#""(("!")#)*#%&
@r6600
AAGGCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTNCATCCAGCCAGCGGCCATGCCATTCAA
+
A15/%21%,E/8&8E94&*D80'1!(*=2"!.C16B(HA<=5@HBD?$5*,8:EG;<1G"H-,F=.)+/G005;#79)=BH0?$-",7+1/:94>-',&H/(D
@r6601
GGACAACCTGCACGGACAGGCCGGTATATGCCNACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGT
+
$'(9-27>..>(,>'.A43!@927E#G=58)&4+(1@/9BG8470!E,),46%6B=@>-@5E/B4@>?5%00?;##;25/(G/-6/%G.>@(C#5.
@r6602
CGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAAC
+
18*=A(##E#A$H#D4).,5.+3A0-)@!46+*"@H+3=*0..A/A'CB3!B>B-&>*-G0
@r6603
ACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGCACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTNAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGG
+
<*?*!%H*52.%80E)=4$A;*/B%D8E:/28FH!#A-D#=E176"E5;2*/;C5-BA$8=3#">.=!H@/(HH#@3>-7!:.9E<"=;;?,,+!%B'D-,'$A+-F1>#7F5"B0$#/*)#.D7;!#?C92>?&;"%'C+F1!$7D27#?8)F*>*!E(+C$G6.A.??)"<;%EEG4DC:>3:4(43>74CC/E08/"7((20',*#-@=F;HA&BE@1*60H9=&;+<0:F,6-8.DB1E$."-39HF/%25E(-A)H!%$"#
@r6604
CTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCATTCCTGGTTATGCGGATNCTTTCGGGAGATAGTAATTAGCATCCGCCCAT
+
'1C'!/<,%'7(*./4&6A1%!="C;>><@!&D&-D4$=<'#0E0F:G$?.(E.80#4@<,;-<'(G8:01=+=4>.F6>,*&6)53(/7.B=-(AC+,A5*714042!:8@#H/BA.7(*!$/D&2B8-6:3@
@r6605
AAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTG
+
6H05F&:G&B@6!4'3?G:")!@;@;!@AH#23G+99&--97C!#!'!)66,$7@+-*AE3-F<=3%BB'!<&G98G")>FG&*=(G.&8$!=
@r6606
CAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTNCTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGG
+
)(774E$?:F8=9%2B8!D3(3H9>>,G79",%*45.;1>54#/F4D>=9=67H>*?/;!F)5%>8C58D?@B;8!3$;%FBB?AH(9A'"4&
@r6607
TGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCCCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCT
+
)A(A@6#,?F4;+G/(>+?6:9#H!+77#@#<2>1-."E/G3)<;C&.F(&AG'9<4>45B#62,5!,-F%3$"05?*?H04-$%,*5;6AHGD#-3.''+6>C781A.
@r6608
GTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCC
+
H#)GD79$(A,.D/4F41GC;,8(D#/2(BE"?2-='#"/83<
@r6609
AAGATTTTTTCNGAGGGATNTAGAATATGATGAAAGATAGAA
+
@H3(6*0&7F='$H6,5()$$BA<&:==!?B=)G&2!>$)%,
@r6610
TGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGNAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCNAATCTTCATACAGAAAGATTTTAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCA
+
'-1F!G85B(-/$F4(C5E<-D".%7G?37A5>9)36-B'+)+,807$&!D++>@H(885.?4%79H-6C&,'G:A(/4G5F@EF2-0*418CF54'C%@/8>@'D94$5+?135>%()21F3D-9;B!F@&8)@BH:/GG(@&C#7!;-."8+#9>)F@22'H,9B0?2D!G?8F*%947?-B05*'
@r6611
CGTAANATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAGGATTACGACGCTTATCNGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTA
+
&%"($()++$$+#%$#*(+$*!$+%*#'!%"*%##*#$%(&&#++()*%(%%*%$!&*&$+"&#)()"(#'$&!+*+)%%#"$"(!%+'#&(%$%&#"+%$"!#+)&+%($%&(&+!!!%+"*)#"
@r6612
ATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTAACGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCC
+
;:/C?4%H+1*-,3A450&:%'&?4,+;(#%(4$4!%EC&-@'1">2#'))H&&C#(C'+58G11=<HG0:?2F9+2E>.D=/
@r6613
CNGCGGCTGTGTNNGNANATCGNCNGANGACNGGCTGCAGGCAGAAATGCNGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCG
+
*"*"$&*)!)$*("*"&!)*($'%#'$"'*('*++$&!$!*$**'*+$(!'"'%')"""#&$")"(!+"&"%!))&&+!!(+#(''&!))&#)&!+!#'&#*#$*&"*&""!'$+"##((
@r6614
NNGNTAGAAANNGATCGCGATTTAGAAATGTANAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAG
+
"$#!")*)(**"$&%#($*%)+)*#++'++++#('%)#(%)*&#+&+%)&()#!%($""#!!+"%"&"!*$!(
@r6615
GTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATAT
+
G:?G;%F4G&BG.8GE9'2*5B5#"%'#87$H*B"".8D;E$D.DE5#)'8(?80(?;<;6449.3@<'23
@r6616
NCTCTTTCGCGGTATCCGTACCGATTTCGGTANGGTAAACCCGGTTTTTGTTCC
+
#&E&!+C*&%$272+<@>0+;7H@#D@?%A4%/(6&#?!HD/B!0D!C$8G9F@
@r6617
GCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTATTGACAGCGGTGCGGCGCGGNGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCCCGCCTCGTTCATTCACGTTTTTGAACCCGTG
+
$@,/*,03:48(41-?:D37"&.!&C)A0(6">>7G/FA3(?+:;9&2)#H:E14FC'<5*:3&B0-+"+$#3,;<$?9D"=E.>5FA/?&C8:D?+6/D$AC3F(*(2-,C7!9"HC,'"2('?CF*E'5>1EB&8%=6*F3(9/!9B1,#8$!5/A3"*8E?+!:=A.
@r6618
TTACTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCTTGTTTTGAGTCTGCTTTTGT
+
%&+$$&!('$!*(!$*$%+++)%'#'')(("'+)""$+$!"*!!!!$)))+"#%*$%#%***#%&)&(%*$#))***'+(+#(%(%++"*"$(*%&)&"(+!"&*&*&("%*!(#)!&*&*)*("'##)*!"(&")'$'*
@r6619
AGNNTNAATGNNNANAAGTNNGAANTANGNNNCATCNCNNNNCCCTC
+
#!"!"!$###!!!$!"##!$!"!"!"#!!"$!$"$#!"""!""#$$#
@r6620
GCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCTTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGA
+
C:,:@=E"DG??)1+>#+C%73E>B/G(+(<.<7GH*H-9+G"?47>F#-%"+0#%@-&FF2:<HB*3E0H=8"!'.0C#2<5'(3#-5+,>F+H$7E%<#5>#'?D?@*...(B+H:-25D)A3
@r6621
CGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCNTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGANGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGG
+
=0@?%:'&H0+G<D$83BF,<7<BF',8A<A'@7$(%3@!FC#<)9:?9!'?8;$0,0HG!G285-4:,=1+&#1F-#:)H"@%@<9@2GG:G&)28C/1C'%1=1/196<'HGEC!E:$&8"$&9&G&*29@$CD%C5!%F<%
@r6622
CAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTAC
+
FF!;&#D0!%>#BG($%HF,*98*-/#6#8A.?#'3@89%1#%.<?(+9-&++5!8H<.6F#-*F?>:166"AE?D3$471/5:<;&
@r6623
GGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGNGGTCGTGTGATGGCGGTGAACAGCCAGANCCGGACGCTGAC
+
5>4>>*9C&*$$8H%0#H;&&-!C:853A=:=7HB#DG6&3#8%%+&G;$&2+A5&$D$AD6(FH61+#GHG#25"40F/-+-$!<5>(+$56":$?E6)4@6:)F)6*
@r6624
GNNAATACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACG
+
"&"(&&*+(")(*#!!##%&")(*(&&"!!*"!'!&)!)$*(%$#(+%"#+!(&*+%%+*
@r6625
GTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCTGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGC
+
@1.+;H4:F4/?+BH0"#A(G7)#@612EC:>H0.1:E#G+EC0++13<D%!*C"456)8&"E*(,1!"9*F-04B-3G;9)9<#%3'0#:E)DF2HB@7E>37CG8!>:910$@*A".'2()
@r6626
CCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGGGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTA
+
)8DC+.-*(0FG6HGD9G708/<3E+6%&,)0'D*CA&G=4>0>?H@#+?.9)6%5@<H3.4=;043/86?!/=!*=8+8;E.!<?$:4:$5!HF%(7&,<"/%A0F)>ACB8<=<97
@r6627
CTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTA
+
G+572!@>&2#+6.?02B.1C%3,E%#G>2A=%HC&%EF?BC?08"7HB"
@r6628
TTTTCGGGCCGACCACATNCGANCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACANCGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGG
+
H$%C4""&5)'D;'&.(:::>%*5&'B>BB=,4@+$(2CE80(/8=;0AF)E7>/".+<4)H#))15(>,<@F69<EH1=1HF)AA%HF..&!HE$')#E$?9$6#F0@>0DD3';<)@845+",/:GF>'";F7%+.5F%)E$BD35#8B:H>CD-/,9GE&2"<A)5<=?+-7(+"*;)F"&539B(<H"B0%;?'C:2&F'00/0BD9H"%*%!,"#
@r6629
TACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTC
+
<@6.*>*@6:/+@H%HD;*(,56:.0C7H"723+.F*?BD/<$!3!#7DH&.G:F-26H>.99H1=.B4D3(C?1CC6
@r6630
ANACCCACAGTACCCAATNATCCCATGCAATGAGAGNTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAACAATCTTCATCGAA
+
&-/DC&)#4E;"!'?=<F4;C?D=7@$!)B9;*<-29,%'()3*@7<7@@A/;(F'D*%<4"1(<>0CF31)?B,9F77A9!,>.96,E=!)F9<>&-7%!/6@/?>(1"518:8*.0A<3!%3&AE+8HC2G&%%D35-8#>.),=>ECC@?>
@r6631
CCACGATCAACCAAATCGCCCACCGAGATNAGCAGGTCTTTTTTGTTGTCGAATCCAAT
+
-$#;>.;#&)"@AE8:2!7&;B"6)GH'/>CE5DED9@5A"6"!3??A>+/!/)2.%@G
@r6632
AGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTT
+
."<@77-1F'26)=(#:),)+@/?.;/%!=%?D;(H#HA%6H
@r6633
AAAATGAGGTGGGATCANCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGTATGAACCATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAANCGCAATGCTT
+
=DE69-4*6&-1*.@4=*)&A25#*%EFCHF1!%D1C%C79H5=>%6E3(E,'6)+@FF')B).@%:9$'G%A<FFF+F)C4/H:%4G2@:F-&/28('8H6*<5@>?C@%@9!"0)@/A.*2?!&)%!0(.66=-50<=;-)=!#A6H$+BB1)G:$3>%',%%82H6,4(CGG3)+37-'65>%105D5G:#F<B6C7)<@9%%#/.D&03.=B2C,3CF:E+'<$7A1!8/@
@r6634
GCCNNAGCGTNNTNTGGATGGTTCGCGGCGGCATTCATCCATCCNTTCGGTAACGCAGATCGGATGATTACGGTCCTTGCTGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATG
+
**$#%"*(%'%*'!$*#+&')+&$($$&+%#)($*(%%!#%$!($**)$!%+++%"&*+(&&%#)*!"'%*&##%)!&$$"#*)'!(&'+(%#%)*$'))'"!++##"&"*)#!%*&&)(')$*()+
@r6635
TGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGG
+
33(FD50*%!E:",>D<%FADF)'$8H)%9:@<>@'?2648A'=8.C(E'9EE#25F/A!$:.#&<
@r6636
ANAGCCAATNGNGTNNNGNGGNANGTGNTTTCCGTCGTCCGGGNCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGAC
+
(!"&)()#'!&&()!!%)%&*&%'&$#(&+'*"+!!"+"+((+#'!)!+!!)$)%&&"'$!#**(#(($(+#%*$&!!)'+)&'%*+&!!(
@r6637
CGTGTTCTGGCGTCGTTCTCGTACTGTCTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCNACACCGGTNCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTG
+
*)$+(+#!(#&)()(*(#))*$$'$&((&!+$&!(!*#$)(**!+"!!#"*!+!('#&()!&$!)&'&"!&(+)'*$(($+#++#$+#$%#'')'(#%'$%$&'*%+!)&$#)$#$#(&&****($&#$(%'&#"!(&&#)+"(&&")*+((#)('!')%(!*'&&$'&!"++'+**++"%"+!("&("'!$%"#$"'!!
@r6638
GCGNACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCNGCAAGACTCTATGAGAAG
+
)'GF.$5'18"3"?0!*8#?!:GC3/22;91"G8&'!B)+,3-3>D)**'%,):C1=!$=68H31#E*@0..:;!(E0,B&-.4)G;>8
@r6639
CACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCGTCAGGTCT
+
1C7):153E+FFC?A"19D6D0!=AA%5;%''*E5*88:C+F3<(
@r6640
NCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCA
+
/8D0$/&9E+-*:BD'A?2;<=$+A1->@HB0376(0/<1A&(6+A+B'/0>#1-F&64>(*D3GD;,*)B.5?BF1=(/@'>69@H1D<G3*F,98DH:HB-/4/CE;!(B0D.-D,1=
@r6641
NTGGTTGTTCTGTTTACCAAGTCCTCTGGCAATCATTGCCGTCGTTCGTATTGCCC
+
".)=!2-"-,B>!6'DC,-G3D617119G=-G=2B6=;*;-";BE#(/8;0(&%D*
@r6642
TTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCA
+
4>A?E7&7B9D37@5D705<DGBA2%"22+)'()%B@7:9+#9A'-F&!&F7C>&1*D9@.@@7G@+-HH7C!DE)*08H**20&8@,67AEE9,*.=@D7<02:F?;!'&%.:)%@(G0
@r6643
TCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTACTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCT
+
154D=#>B,<E9!=3@HGE(FC"(>#8G.,B4$/*;$$=2"7F!-6)4!&G9:F0/%4C!@BC9#")F*.E.)9(<.!D7-''?6-H0:$(G'>D7>:@E@+4>>A37E0.&;)5'!*7%$EB07D#H!%E5
@r6644
GCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATG
+
C!8;9EE$5H.&F9)*A%.'@A2%%D<B';9,!CC-1=*;*,29@E3DE(!$2)(:2%.5$2;!,'6#?G9E@5-226$95C:$B8(!"+.4+G**38&"'#"3!4
@r6645
GCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGG
+
$H:"!&&5,02+&E.38**B85;*G+*3>+8-H5AA'9AG;G#2H=&+?-:/4@E;H7(=C(C+"=C/+<,5:'2=$H!)$=4>)C<9HD0?#,7F*H7%//)FB:3'%A@-#5@/@74CG0<87@9B@3%H8+#,#
@r6646
ATACNGGANAACGTAAAACCGTCGTAAACANCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTT
+
&?#4+@#(;1B?&3*#C*F(37$0D>%9%)F*HB63,1C%FB8CH7)9*(/)4@608+;C<5,FE5:*++;"+)25=+;ED<;<==%!!7(E<-%<(9AB;%6A,0#A!A(F3%$;;(=%.&
@r6647
GCAGTTTTACCACTTTCNTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGATTGATTAGCAGTTATGGTGNTCAGTCAACCACCAGGTNATAAACCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAANTGCTCTGAATGCTTCCACAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTNCNATNAAACATATTTTTTACACGAATCAGATCCACGGAGGGATCATC
+
@:G@;&&,8*-53#(@!1!C@"'"9!A''$B6@4'#>#7*B?.F!83//1*"2<.49%F*!6:6",&G8&769#E2"2./'00$/G,!B1H(+G#?A*+D))!4!6/()'>EC>75,<D+*=?,<GCC<F21>*>*5*&0H=)>!/3(E<80-&<#7>:)-""<$F4E0:49*=D4$=*857+B:%%:EA?;GEH.-8$E'52$%#<1?406-;E'87H>.7@'H,/+.4:?BG/@(,>:>F8/8**HH-;)&<,GF:$,/<@GH)F57+%?G
@r6648
TTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCG
+
->,$:H*H;;G96B34=*7D,(4DB'92+)($..C(8-./A=1EG9H'0#E9),+G<7#*(*
@r6649
TTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACAGTTATCTGCATCATACCTTCCNAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTA
+
*A7+>:6E%02"4E+/!=?GC/&C.<H%',"'+,7;&9@D0>'9+G?94";@D3).&B7#B!A'!."C&7E@@FC841-!,(-%@"8.;F<7C5?8##*16E8F@--"@EH34(%.B#8B/577!!69)A=)E2)DC!887B&G/33EAB-"FA).>@8>?F;>',9(-9H,,7.=CD#15+00G(/G?&&A.D-H'E1!99+56?27!3790''/8+'-"++A"AF$62AC
@r6650
CGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCG
+
49=!BH6#A78<=<ADA:D=%&GEA=)#:4<'9(C!H&<B6"/2B*C0)#-.A%A$29H*%-A#G;"1@AC5BEEH*+(=B(6>!<)@E
@r6651
ATCCAGCACCGCATCCCACATGGATTTGNATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTG
+
>1#/C9350+$!$:=G"(.1,6'*6F.D!>4%<.&0;%D;)56-,,/>1/HC5"#G3+?&=)"!7A#
@r6652
NTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGC
+
-'5&=B+?=8'9%<46,3%*5**4:"<G#44/-83+*G2&F%>?&#B."%DE?/;!%#3/<$$AB0'5-7G0;$4=@!0<"H5GH
@r6653
CCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCA
+
@BGB9<7:F='8"BB,&+19=$@8$6!76)?;GA<,>/6D),(,B/FB#831@?%-%976$6:!178+,?*9@377>"4*<;!#7719@,)%C@*>*
@r6654
ACCATGAAGGTGACGCTCTTAANAATTAAGCCCTGAAGAAGGNCAGCATTCAAAGCAGTAGGCTTTGGGGTGTGTGATACGAAACGAAGCA
+
F%7EC5=+($!G81C/659-48>;0&)A@-6$&4.=6,4!A5<#3>%>F:@(7>E)%/E>H;F5%((D%$==4"<.+62FBB573)+1'>9
@r6655
GAACGACNTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCC
+
C/(#.,73H*.)-/.8!@F$.2=/;F*4E*+*G+1*DH924'3B%8:,(#H<!*-9H
@r6656
CTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACANCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATC
+
(H$"*,?9$)?5/%07+7B$*,'55>7C?$866?D!5B),A?-"?=$H=$H.$';B%2E8"186@@++>?7"42D>-71A!=;D!2<%9%H"%.(!D#9!BC+%.!9@!HHF?%-18F(>+#A+B;++>B1F7=@="444>=F5."#,
@r6657
TCGTGTTGTCNGGCAGGAAGTTCTTTTTGACGCCGTTTTCCATGTACTGTCCGGAATACACG
+
;8+!)4.71+=F1EB9?'$0>8@$*$A*.+8*70*</C2F%+-!&*F4</54F=4.3?<D'E
@r6658
TTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGNATGGCCTTGTTAATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGNTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATNTATCC
+
.E"E684D>)&D;.&H3;%/%@98/&=EGF<C@D$/-!0=-4;'1C/(+H?6B93('&DB?*F=48<G'@.G65%0<.2DB.("8+9?H'<G3/'7*@E3".'>?1<.+DDD77).!1AG087F&-D"D$<,(?CBC'10:",AFA:$.>)E"6>F,#:6:3*(A))<5>,<3&D$"H("F80$E(-"=E.('E'+?2<+?F&'!86A!75%D+!+F4+3>H*C)/C4"4>*7F)#:F#%!A=>:<$!G=5G?=>!64DA#>/!<B*
@r6659
GGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCACCCTCAAGCCAGAATGCAGAATCACTNGCTTTTTTGGTTGTGCTTACCCATCTCTCCGC
+
01*G6C0)E@E=+E35178">A22"<8)!A>*&+1-@-<@;A$%1-8.F?4@>2>9?DB/H7>#BD<=#5..-5"70(=->()0;>@1+;;4FGGCG7
@r6660
CAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATG
+
+%'&+(&')&%*'&##&(!%&*&!!$('*!#*%*#'&$!)*+)"!#%'*
@r6661
AACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGNTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCC
+
@4@?E541$.;+E/"$.9-=1!1#*"6E*9)C48=#*<"C&.?H.9/H:;@*!-4%F4.!%*27,@0/@$@262($2(:0!F/H7E*,,=#>-292%"&<F:*B7$?!B0(0-<D!0H"20@7*+A>,HE"$7D+;F1E"C!9H"2!3,@B'"1
@r6662
TGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGANCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTG
+
?/:G/H-""7)%4B7CGA&A/0$>=G(7&#F&-5"A,042#,:-A:H%DB>G<5G$3!-0:'32%D6$,-981?=).?(A;'>3F+8?H!<,%-
@r6663
GATAATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAACGAGA
+
E+1'/>2A4,:8>&BF3?FG-F)(<<.1;47+!/=H5E2;E7&"#@DC)G?+*&'4=F=4F)"87/C>27D!2*(<=57>81.&:6(15<2?+!%B1$707/8"16FB>=):5*%6"BD=DH04&(3!02+9-!G%0B1)81(!F6:>&&/'AC*F0
@r6664
GCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTA
+
HG3'/23*-B!9+"/,537<3/2CCB):?!15"#6@<;.43C"D3.>
@r6665
CNCAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACNGGCGTCATCGCCGCCCAGCAACANCACAACCCAAACTGAGCCGTAGCCANTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAG
+
%%'B7+3C@+?(!1+=D0.!:.<8;)!-<37,*.2"E/43)B/4>07,;.))H$-C*"#H#=B"6%ACD70;D,,0=>%E@.,3--+G01:F#F+,10>,@(3HHD4&5A26=B%0!><F+A,.D?=FH>6E'!#?-38,D5;9=%"A%3GG8F8((/*9GF9*BH#!30F0E!&".-D9)14#?E=!:C:E4.-C3-9H9$+F2!FB.(:13*<CB3>!$3/!35#G</+0*!+:=F2
@r6666
ACCCAGCAAAAGNTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACNAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAAC
+
7,1/C%AB@,3F2G68EF"%1FA-1F0H@F?@$%>G;"(+D/58$@.$,<;%B".;F2@01(6E%,4<)76!=)4,-8:"/+7HB(063AD::(A9+/+F#<(0>'GGAB&=@-A7+)C+7C*,@&7"-<C+'=G43)3C-7<!718?7*?6+E:E);&G)%!&#ECE?38"F1/>.&B
@r6667
TCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCANNCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGG
+
.2/39=5F7594,"FC/=<;?2;"1/&E>G%.1@!3,)4E!6<7%C7%@0#>$;*0652<@5#(@!2+;=37#()<;<%AC?G(%2<F.E8,<@''*8=DE08:'GDA0/,H>3!G">/A?-1H%1$(*=D$=CH/*&9!-4:
@r6668
CGCTGCTGGCGTGGTTTAATGNAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCANCCGGCATGACCGTGACGCCTGCCAGCACCTCGGTNGTGAAAGGG
+
$<.GE7;'G@(&078>'D>GB$F2'="BC/27FBEE&H*E89.D,.,#*69/<8=D.0!,.2D-(=,H.!BF6D(B*03,C2G8?%=&)+3,()H)B=F868B1.B)<:($%4#'58.EG>A7-E*</E#,HCH.=/E-"3%C7?67@5,%0C;"A=DCH9852AF85;36;E9$<6B:G*D:1@8D*H*(FE4>)F&,(*!D%$H',?$>8'8<"<>?'!B:B)-F%5>E:A43>+#
@r6669
NAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTT
+
#7<8!'""7?26A33"-%>4:.7='H'"")#=:<>:40G:--!F4%A;*2$)0:0G;9/'')5=0GC=/,#A$:*&'5'F7G/!%C4)=/=F+D>02"!#B=/(<+)$:A%650">>587%1/!51FE<+;
@r6670
CGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTT
+
>%="#.&"&!E820G"H#.H2:FA8?G:-&@CG!=<C(H)>6=+'0H
@r6671
NAGTNGANAAANGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGNGCCGGTGCGGCG
+
!)'%''!$#*"!**)#)#++&)%#+'*%$)'!%$$!'"#&"'$!!*()$(*+"'&%$)""!'(*&)$&
@r6672
NNNTCNNCCGCGAAAAATAAATTACCATATTTTGCGGAAAATGATGCCGCCAGCCTG
+
!'''(!!*$+')('"*')'&+!)'!%+$(%+(&*('$!$'"(%#'$''"'#"#$#(#
@r6673
CNGCANCNGTGTNNGNNGGTACAGCCATTCAGGCCGCTGCGGCNAAATTC
+
##(#&!(!$#"'!#*(*$+%('!%"&!+(!'*%&#"!("+'&'(&)$&%*
@r6674
CCGACGTATGGAGTGCCATATATCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGA
+
03'$@,,.#,/+1?1:&$+/)/D!##)..C'DH=BB7'@G!<3'"4B3-:'&6'%9<'!@C:.=;+)G6)5;@D+7E!:,8ABG&F.D)>:)#>272+@G#05075.12=B=G)5<1(&C//2;/(:GH!<$B-"C;B,0)@;G?3'>DH?3:G*D/'666A>0=E:1G*'2+%:!=GB9;2&7%+<7BGAH+'(5A(
@r6675
CTGTAACGCAGATCGGATGATTACGGTNCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCT
+
*"B4/3=3GC/!G<?9F?#=+0"3,H-"A"G5;5B19GG*'*6*B*C$@D+"'*;645BC9;,3=#,HC
@r6676
CGAAAAGATGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGGAGGCCCACGC
+
>7:'+"903H-(@:%5H&<?0>4";@A")>-.'G+2+%6@@2E<!)>5"6#'1"=:$/F)>2-AF2A/*.3D#GH"F,4=7C.G7->*4.(F!&$GDH-$?.+@";:EB2C
@r6677
CCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATG
+
%)F6<B@343@2=<2'#=00E"7D88"D5<):G)9.+<5!)C
@r6678
GCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTCTGTCATGGGATTTACTGCGAGAGTTTGTTAATGGAAAGGAAG
+
10!8=&?&7/E21$/'."4/.E*F=2#@.35B6F-+05>;5)79-6;0!5H!:8-3:'$9;;6=3%D+-&,@H3@3,8(7+D4!2<AA*C;E2B!CC%,
@r6679
GCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCA
+
>83+'(4<%A;;BD5G@2@#&!7;$FFH'":06EG<4G3=428):D6*G?9?
@r6680
GGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGA
+
;46G3<8"?5'A=608>0#<@6?64@@E-'*@;.'(.**"A?:6H
@r6681
CGGCACGAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGG
+
0"G/#D;61:&D1G/!,9>;)94/?6B&/2B%EB?//A7%?"84A1.CE??5F-828=:&
@r6682
ACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGNAAG
+
F3%&6*64?<0#DB!>9+/CF0;''.6-8@="/=$C.&<6D59;-06A:H@GG4+*/;F5=)()'>:BC?&C(E48D%"4<<4,A+*-.?.6-=
@r6683
ACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGATTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATNTGTGTCTGAATTTNATCACGGGCNCCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGC
+
'10"A/4&;E;$=B=7?4D.B@76=BF#:;=8$*"HB33=+F+3>="9/?G5?CB0.,/$(AB>?+/2B-)3@D384+/B3;B$',1%$*4"CDGFH$6)0@0B845>CA164:%3B:$$3E&$2D<<!5=+))6@:#C3'-".:25DCA-4>-=5$?2@B$%-'0(/>!*-8)'7FB>/5>3;:-"+('71&@F2$,0/?&9@-E"33953'C9>&72!'%F&@C5GF+@9,@-)1!8?D+D>D4,%(D,6.8!+D!FH$D*-,F&'7"!84"9(-AC**.<6>G+0/D/*:%#D!%A
@r6684
NATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGA
+
%H*?1B/6:/E!*@:#)F.+',F4E/0=.F1B:7+*>8E5?149A4;7*$?G90$$FC0+3+'7,"F&F8$3#0/@(6-/>-73A,/?'&/2$+CB).E292G94*':B!0(7;G"?F
@r6685
TACNNGGGCANAAATATGCCATCTCTTNAGCTATCTCAGCATTAGTGACCTTGTTCAGAGGCGCTNAGAGATGGCCTTTTTCTGATAGATAATNTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAANTAATATCCT
+
*#%%'#))"*("++!**&%((*%"#"&*'''+++!&++)#')#$!*"'"&""#"'%%$#%!(!"$'&)*%"#$#'(*)(*"()&!'$'$%*'!#$'$($*+!'#&!(!($(!#+!)+&'*#'''+%'!!*%&%!#"'!#(('!!"!&%#)"&)"&'%(")#+#*(!&)%"#("!&&$
@r6686
NAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCNCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCG
+
32-1&61HD!3H%HCF+7A29$=A-3HC>E-$!7:6:2+60:*9*.<'-(-<#=E)@,+F?*!2+,=0"451667GEF7>6&(A-;C,5/1'?G!3.C;"!<A-D"%6##FB'2,>C#-"<?H5G/G0D!
@r6687
GACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGT
+
864?!)B<!9')/+$5+*%D%/0;C;FF@8C5"*297/854
@r6688
GAAACTGCTGTCTNGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGG
+
6E,E)>7%'%+4DGG;H6!>C$(AH#:?@07E#%58(/*A0E7,F/"C7*0.:"5+<?F0@
@r6689
GGCTGGTCAGCACGGCCCGGACGACGGAAANCACATACCGC
+
EH:D$E@"/%1@:9/>2$H*':&=E;,7$>8?F*;))8@'7
@r6690
GGGTCGCCCCATCTNACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTC
+
?4$6*4,:$"<)=7>$3D$9;31)=40DGF%5C0D(,5,*$2:F$6G5'<2
@r6691
CCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTATGCGAATTTATCCGCCTGCTGCGCCAGCTCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCC
+
@*5>F+.5A$(3*,>+$<)"899-#D=A:;'00,@*/&*H5'-/90,4(8%))C>:GH5@9!+H<G'4*'"44&H@&=21%0>.A+F0F3/+"/)$952>3=+5D>#3#-
@r6692
TGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTA
+
4E-G=5/'@?/>8&-C&8037#G=9+F2AF2=H!7F0#::#!,;B=C28FCC;A&D&&@H&.A&%C5#2=65A43)7#9$4&&@;'
@r6693
AAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTG
+
(?)E:H=CD.@:0?9DF10#6>7HD=%./<C)5%!#)-8&;1)C
@r6694
GGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCG
+
'%1D3#/C:4&;+98E@?)D)GBA(B@70H!?58""0050.<<F<AAE&;-3,,$7"8#=&"6$D<%&6CFHEH!/5
@r6695
NANTCANCNGGNNCCTNNNTNNNNNGANANNTNCAGNGGNCNTNNCTNNNACNTTCAGTNTTCCCNNTTAGNNNAANNNNGNTGTAAGANGTCNGAACCAANANAAANNNAANGTNCCTNNNTN
+
!!#"#$!"$$#!"#"!$"!"!$$"##$$""$"!$$"!"$"$!"$""#!##"#!$$$!"$!"$!""#""#$##"!!"!$$"!$#$$##$#!#"!#$$"$$"#!$$#$$#$#"$!$!$$#"!$$$!
@r6696
NGTGATGGCATACGTGCCGTCGTCGTTCTCACGCATACTCACGCAGCGGAACAGTCGCT
+
"0*?C@(<:-/@C:9:(36!:1C*9'2)4;@/3;*<-@@2G8>*-$.BG4&B+E3,84!
@r6697
TGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTNTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAAC
+
GDG.')>>5:;+G?-=4H0/GDBG,H$,>$GCH)52C*?H#>4$#F'':F#$%+@8FH>!D<3#'#FE(!44A(EHA"H0320#5;?<!03*A>5:'5H!(1;8F3D))=(!4$G+F-">"*?B+H$/!4
@r6698
TGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGNGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAAC
+
@5A13!C#8B#E1$B+#:"5)A'G/?<3/9)C(<(<!"!C#-00-='1%2?@3#-EH;-=6E9/,07>#$H#@($$A.?3%3;70%,@3/;E4>A-!HH=H=8
@r6699
TGACATGCAGATGCGTCAGCGNGATGTTGCTGCGCNCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAA
+
?+1G%A!E8*-%:75+H>073=(F7E-8>#3"?;6<#?*F0(A>62'%3F:%6?D/7%0C'1;,A$9G="+01!@8G85
@r6700
TTCACGGACTTCGTTGCTTTCCAGTTTAGCANTACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTG
+
?1,(#>$A%"7FD"&?(*A3&)%-9HC<$@D$$=A<DD.C10!AF1#5ECA:F)-4@B6G@<2>D315F!(%>."1/A))H$7<!
@r6701
GAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCC
+
+#,G)=1%480*8)$42<*!0%3+;%,6'=GC)FH+.G8<G-H$'<0-/-&9C/+
@r6702
TGCATTTTGTCCGCGCCGGGCTTCGCCCACTGTTCAGGCCGGAGCCACAGACCGCCGTAGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAA
+
!)'$*+$+%&*(($*($%))(#)#+#)*+!%%)!#**''&$)*&"'!*#(%$$$'"+%$!'!$$'$*+'&*)&%)'&#&*'*)(*&+)*)(+!"(*'%!((&!+$*$'!)$(''")$!""+"#"
@r6703
CCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACG
+
=*?1GEE#@'.+<)5D5>-/E*1*,2>.H.@,22)H+#@>)6=%H"@?#6D#F*%B%@8>&;1E#,$191-F=!C&*>+$<1'=;"*3,AC,..B8
@r6704
NTNNGCTCGANNCNNAGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTNAATCCGGG
+
#'!#%)"($#%#&!!$+)*#&!*++($*$*'*%#+#)&"$!()%$#'$!%")'%"%(")"+*""'&!%+(%$))+"'+"!+$%"'+*)!&$*++
@r6705
ACCNATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGA
+
"<B*;)#*F4!'9C*DA'1@E93"(972&-B+>5*-''$<
@r6706
AANAGTTGCTGGGTGTTTATGCCNCCTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACT
+
"&"'"("%+&(("))"()("+)#%(')%+&&#(!'&*(!$"'("+(#(#)("(('%%!('(#&(+%##+"'#!%)%%++"#%")*$%*%!
@r6707
GCTCTGGGAAAGCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGA
+
A#,(C64>.>+F'-23@.D5-5=/*D'$<53G1C$9CD?,!6'*'2D6D16%B4'FH
@r6708
NCATNATCTGTCTGCGCTTTACCTTCNGTGTACAGGCACNGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCC
+
"(%%""#&$'%(+)%(+!&%+(!(&&$"(#%($&("'#)!"$*+!)%""&#"$%)+'+%'!'+'&'!&#)"##$'%!'%!+&(*
@r6709
GTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAAC
+
1$$!:2,B%65(#>@F'BEC,:EH6@AH*&B+&,!$+GF7A7:*3G,A.<6C@)1;,("?F.,D!?
@r6710
CGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACNGTTATGAGCTGACGGNCAGTGTG
+
;;683'C/?3;&+')F?930>9.FFF+F*+>17A=A/.*%8*1?E+>19@G#>>&!#=)9*>#&>86$7@
@r6711
TTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTA
+
57A'!+@$;!@-*/-H@DAG);$:4B+197&-(+H66*'<5)F$:3!%
@r6712
CCATGCTGTAACGCCNGGCTTCATCCGGATTCTCTGAGCCCNCCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCT
+
H0*=+/#3#5;$-4.-%;%'%9#?)EE/"'4?!+?:7C0**G)21+*+CCB-C:D-9!7HG5-#19+"2;-9B"3#6=(G?-GF.GCD:6>=D.2A.A=AG1,<('89@,#B<5>%,/H?&E./.H!A5?F$DA85HE;8EB?$(F6%E!!%"4D09>!;@$7A9<95,EG$<.&8)E5.!(2;A(3+@"<HHHG-%*((/5B@)"6(?='$0-=B
@r6713
ACGCGGCGAACGATGGCCTCGTCCAGCCAGCACAGAAACATCTGGCTCGCCTNACGGGATGCGACGAATTTACGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAG
+
)+(##+%%"%(*+!!%$!&)#"##&("+$'&"+(''%*#&"')"'+%'**(%!#%!&+(*%'#''$#%*)#&'#$&*$("+*$)+'&)***'&++**#+!!$%+$'%#"$&'$$"+(+!+")'(("!)+
@r6714
GCCCAGANAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCNATTTAAGCTAAGAAAACGCATTAAGATGCAAAA
+
<4<B>/F/,,BC')/4F:30B>GB5@.@9*H#%2.A?3CD@>2@:(&DF>918B-:>8/499&#D<9<-)9@D<@B>4)82=HF*53G<D00@+$=B/&7-=#E(H-!83;:3:B682'*=2(7#/!:H=6',%C3CD"A"76#(C-GG4E-D%8:32(BG?"@F'=/H:H+
@r6715
CTGATCAGTTCGACGCAATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCG
+
36:!0('?*74-;=&?8!:&>+E*0B*+=-*$8?),E!-3$,=))&:E3BBA(4,2:#18?8"2546(FF;@*C/B42:C!H"2F+"+95A6:&!.4#C0>4.<)$'77".#?=2%,&3?=4=&%!=@+
@r6716
GTACAGCAGNTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGAC
+
+6?-*!D8DG%**'6?4%&>@!4)#*%0@!D4=/9/H*##/6!;!G4B1*"*71+<G5/94)B.%$7F9&(G,18=86&G=
@r6717
GGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAANAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTG
+
H#-1('+3?/:8@F80.994?8?F(#-.-"18F71(;:')2=A<=,0C,H.",>@H*-EB61@@47;#=6A(9'=/A/7:'8C79F.C)9A',E2D=2;H5/;54!
@r6718
NTNCCGCCTTGCTGCTTGATAATATTCANTCTGACGAGTTCTAACTNGGCTTCATTNCACCGTTTGAC
+
!'!)'&'+%$#&&!!#*'!**)%&*%$"!(!("#!*!#+#"(%#$#%"(#+$***%"#&$*+'&&!&#
@r6719
GATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCG
+
;GG=GD78BF&:%$9G=>A81=7.6A)C;*6>A3*ACF78!H
@r6720
TACGCTGTCCAGATGTGAAAGGTCACACTGNCAGGTGGCTCANTATCNTGACNGGATGACGAAAACCA
+
0.F)D)49'3!B8:C.2/<4@'+C>GA::5$"3B;6*D'>>0;BA7G4)FB)D?6!**3+(%E+>924
@r6721
TCGCCAGAGAAATCTACGAGATGTATGAAGCGGNTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTCTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTG
+
<=(0:(0/FGHG>18*F4B&2BF79<E&'E6/7F!.4'EH60--<'".9!'/+)!(,/?3@G1,,:F?C?1:37839@4-.<?=.!@H;$B"*C"5C2.8:()5#8H4&B)BA$=F3+FD%*?=.-&.%0#'1!"<
@r6722
GATGTCTTCAAGTGGAGCATCAGGCAGACCNCTCCTTATTGCTTTAATTTTGCTCA
+
-6!!'2"&)D5?D>./'?!:+2E(A#1;>2.5)30:3EF;E07)5#1?(EB8!5*%
@r6723
CAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCNGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTC
+
CH7/&?6F+GH68!9G?=%44/:B4%92>"5GFF)4>0GB,,<<7"<F@H@B'2"5E/2,B0"25"'A5#D>@'!E-?<F9;?A(33,@C1/878H>'D&.9A
@r6724
TGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGAGAAAATCCCGATGGCGGTGCCGCTGANCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGANCGTCTTCCGAAAGAGCTGGGCTATGCGCTG
+
7F)6>A4>D190#%*1@0G<$<<%90037:F&8B"*0A5H&-<@-$'9:*4C&CCF-5D3@95..6FB.1"<=&288++6011(;5*-/G,1)=6AF8G17+"<>)0&5E*-B7(>DH>16@9,GGF.7H"!<85!8+8*/(8.-=G4=@
@r6725
ATAATCATTNTCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAGTTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCG
+
.C6HA/7)9;C"H30;D5((365'B.8534/2'0D(06G<+=**(FD6.@B9&&$7<5!/HGD*;B>1-*!5=<AD$C@$G?E+>@#273A/7!2G!&G1D:"'19=/((/?8;
@r6726
TGATTCAGCATCAAAAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCNGAACCACCAGGCTATATCTGCCACTCANTGTTGTGAGTGTGGCGATCNGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGCCTTGTGCAAGTTGCCAGGGGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGC
+
06/7/6.)**#9(F@,$">7%G%E;?D'C-52.D+!H+%CE=)%8@&>:+.F=H.+)ABG>2%AA'2!88$B!G.1H5B@-67E7+6B@0G6:+#1@<<6:A(H"8=1HF$5D$C&)*6@?<;#<#$!C2'H1+<H&34B$'6#1>3#931!3)F0GA,4;0<F)2!H&C$D?5!F-**;!%&*+-2+A?D17)B1%4)>>A>8D38;E%65:G(C-BF:A,/-,&$891CE?D%;1F7"%H5&
@r6727
NGNCCAGCTNGGAGNGGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGTGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCA
+
%!!*"'(*'!%"'"&!)%+'((!+$)&&&$))(!'$%%!+*#''")%+"+$++$*'+%#$"")$+)!#$'!'()##+"!$!(!$+""!$)+#$!*#%#+"(&&'"*%*"#))')&*+'#'(($*
@r6728
ATCNCCTTTTACGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAAC
+
+%0D<'*H&/90$,G>3)="-*E-@)D-*!=67;3#>6C?4&%</,6$&:)!'@,>?%5:<0:8#&<'12>D89,&(/D2$0/17D5D
@r6729
GTTACGGTNAGACGGAGGAGGAAACTCACGCCCTTCACCACCTT
+
*G$(/#7.&+B7?EB/+&AFE44F,?C<"9AD?*&0.?C3'>E%
@r6730
AGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGA
+
-4#B4"2!<4HE2/(H14G#<9H'$%E<-.%('#1'$"D99H,A;#"?AEE/.-2-#C&41?A75F3>9H=1;B%4-,8E7!5*40!;GCC(!C6<G$+0E(0G==C45F4E$(H4,!?;+><9H@@*B?F/;H7E"6&..$FD%/
@r6731
GGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGT
+
F4B-@HH64:7+3H<9!=?$E>+'6+AFG'5C?'996(0G0/)))'FB/(318&+H"0:9D"9D**,@2+;,"!H#7:&07&
@r6732
GCNNGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTC
+
*'"&+$*"*&"$#!(*$$**&""(!&&(&$#%#!)&+"'%))#"+)*)!$&%'+"+%'$(%*!($)&&$($!*%($!$
@r6733
AAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAG
+
)#+)&'""#'*'+#%'%*(*$*#$'&))+)$(%#&+*+'#!$#(*%)"
@r6734
AACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCNTCACCTGACGCACNGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACC
+
C&0<"%7H7C+69%,"=@D(<A,):$/0E4A+;;"D:*46,"3&'-?5AD0#,%H+-1(%F42+>53;DB-/G".995#:C3/:$=D/<D97'6AEF@H0CA-CE<(6G>*>1$C2,'=!"F2$@5B9D69192*=67%+3E</46:(1.74,?1H;-)A3!5A3H:@E+96$='2/H#&(%$*A)>#%+F?E"0890&B%DC1#264H4E!97?G&*1-.0;8?8='G*?51$0<E.H*
@r6735
ACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGA
+
22.B;'?4+%>7"(E:.=<'9;"1D3D*:9B=9!89*=)+""+
@r6736
NNACNANNANANNGNCNANTCGTNTTGTTNNGACTCNTANNANATNCNNTCCAANGNGNCTTCGNNNANNTTCANTTCNNCCNNTCNAANCTTGANNAANCGNAGATGTTCNNGNNNTCNCGNTANNTNCCANAGNNCNTNGGAGTCNNNNTNGTTCACCNNGTCACCAANCNNATNTANNANCNTGACATTNCCNTNCCATGNANNNNTGGAANNNCNANNNNATNNNNANAAGNTANNGNCNNTTNANGGNATGN
+
$!"#"$"$""###$!$!##$$$"$!$"$##!"#$$$##""$$!#$!#!#"#!"!$!"$!$"$""""!"!#"#$"!#$#!""!$""#!$#""#$#!##$#!$$"!$"""#!#!!!#!!"!$""#!$#!#""##"!#!!#$"##$!$"$##$"$"$##$$$$$$!$"$!"##"!"!$#!!#!!!!#"!$$#$!$!"##$"!!!$"#"#$#!"$!"""!#!!!"##$$$##!""#$#""!#$!$!$$!"$"!!$!#"$$!
@r6737
ANNATCNAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGTCGCAATGGCCATTGGGGGCCAACCGCGTTG
+
&%"'"$++#!"*((&"$&&!"*+&*'*"&!!*'("(*)&&)'%(#&!&'"##$#&'&)#)%$')%(#'#$")
@r6738
ATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGG
+
G&>4!9>2>+72.H+&((@!F@C&0(3=;C8'AF@0:18=@0D>%CB#9(6H./GB'E292&>0/F2F:84)5=?0127+(.>6?5-=?6G!$4-A8@#%BD39-(:2G0;F@8E:F7
@r6739
TTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAAGTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAANATTTATTGCTTCTCTTGACCGNAGGACTTTCCACATGCAGGA
+
D43B'0)-0"2967#,>++#5FD+C&>8=!A;B(%9/84=0(@8>0+A"<BH<%11B>$C)4(H9%,<5=.%""(C9ABE8'&"H(1+@A;8-G'A*"9<;6'$@<0!!631)-+/F2!8A3+$%A;B@C"CFE:>C/2F>9'FE9#.E:@,-6F?0*6%+6:HB5*HB&+55#)#38@
@r6740
CTGCATATGTTGTGNTTTACAGTATTATGTAGTCTGTTTTTTATGNAAAATCTAATTTAATATATTGATATTT
+
%:E8-5$8=HE>$8+H>B!;&%F+G/A%8'3;$'(!0)A%6-/)+/<B48%(A6;HC4H8@A>*3=4?3!#3G
@r6741
NGNGNAATATGCTGACGTCNTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTNCCCCTCTCGCTTTCCA
+
)'#$&"'*+&$+*$!#)&(!$#&"!"+()&')$%!($*!!'&%#+**'%"*((&%'%')!)#*)&!*"&')*'#"+*)*&
@r6742
GAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTNAATC
+
B.-C"594BB<5'>1-,)$8(<06C9@7><;25?)8%G9G2C*@;;1"A#F=7"
@r6743
AACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGT
+
3A=9$-'&B:'3?!+@0*G-83527<?FH(;;#B*G8:!&GF60!#AF@'
@r6744
TCGTGGNGACGTNACCTTCAAAAGCGCGCNTCAGTTTTCAGGAAGCCCGCAGTGCC
+
"%$!&%$&!*%(+!"#*%#***+&''&!)(')#'&(*!"%&(#+$(#)&!&)(++*
@r6745
GGTTACCCATCACCACCGAGGCCAGATACTGCNAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCA
+
$2;:=1F4B*A)9+.<G?6-B<!+BEB-@A4*H%8*>%=%;F$)>>+H+?GC<=1::9"!<$?C8'@%?7:&9G@5/5;>
@r6746
GAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGAC
+
A+&;*3*#@$2@'E1%AB"4>6>4D/'+50F175@3,A0&E%;;@/"11589%8:1-F-B;:4-!8H="3%97,:0
@r6747
CGGTTATCTGAAAATAGCCCGGCGTCAGCGCAATCCCCGACGGTGC
+
,084!D?@.0-+H&3!?/14@41=<D=H71!15E#3#?$+/)H"41
@r6748
CGCGCATAAAATACCTTTATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTNT
+
?0""(-E>(!GB?%9/@)AF((H).+,")C61827!B3D'994?1).50A-.E7.$44C7=!'EH8+1B7>;A'*,6E*@.D)G#)/-)'D33%+1*F&7@!(4*C$&-:D#B6>-CE@0#$C7A%4@3C,AG=%:4?G9#B5?(-0#90=1.<(("==8!5/B%7;#B
@r6749
GTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACTGTGGCAT
+
F=A')$8#$-A!/0'GA"F&,<C*2%9+*%C$1HB(.%;/!C0?/#49.F&7E>.+"6H2HBFF:D7/B+&AH6&%64BA1/#<D'F307-,3'
@r6750
NGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATAGTC
+
)7!FA3B>BG$1197*=.16$77&?4!%18%#G>=)-1<4=
@r6751
NNCNNTACCNGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCC
+
!!#"#&#*(((++*'*%%#%&#)%!'&%%+'!+*)#''!!*+%!+)((($%)#(&#*%!*)#$!(#"'#'(#+'%($$&#)%$"#$!*
@r6752
CCTTTAGCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGG
+
(+)$"*'!%)!%#')+#$(((*&+&$%""#&+#$'$%&%#!&*+&$+&('#(!%!&+#**'!*#
@r6753
TNACTCTTCTTTGTGGCATTGCAGCACCAGAGCGTCATANAGCCGCNTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGNATAGCCGACGCCTTCGCATCTTCNGCACTCTTTCTCGACAACTCTCCCCCACAGCT
+
%$+&&('&'&(*%')!%("+*!+*$)+%*$*#**#'&+%(!(&!#*&!+'*)%#+''"$)$*!(*'!+*+!+$##*++"&$(%%#**$%(+")%"&""'&*+!$'#'+)(+%%+&$)(&&$+("#")+&%+'(+++!"%#(("'+*)"*)$#%%!*%)&#(&&+"*%)*'!+$%"!((+)*)#++&'"
@r6754
CTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCACCATCCCTTTCGGCATACCATTNTATGACGGCGGCACAGTCNTAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGNTCATTCCACGGACAAAAACAGAG
+
=>.>'$/A#@C7(?F7:=2@-=;&%'!;!82?93;2#99492A7H+*=&/.(2B919)9'$3!'4(>*;4&:?A&C!9&?:#86!,,;&2;D06A*79/GCH*F;>58@$95,:H0,'5#.,#3<DD>";A8A&;A))6D47<EEF4*6%$@-)8%9*</;/?8@;/9/;,$$C+36B#,1-B242BA!FH-1F,?+=3-CA7=%=$00>1C?<:=)4>CF5,%B(/A
@r6755
AATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCT
+
4.G19(CHG"8+49;.6*2D?%?*):-B.9!3<;*22(@G'>-D7$*#F7@1$:<5/D'G$?$2(6G$??H*</9'B1A?35H32H&$-B0A66=,./?A%F36?B)%C
@r6756
GACGCCGTTTTCCACGTACTGTCCGGAATACACGNCGATGGCCACATCGCCATACATCCCCTTAT
+
HA8%2$2#'344;8%9#GF/A<>6)%F/07;)-=-1+$8A,5AF7D57D34B5@4-56/%E0F,6
@r6757
TCCNCAGNNCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCNTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCNACCACGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAATGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCT
+
($*&(*($"%+*'!%"#'+)((*!')#+("!"""'$&**"'!$#&&'!$#+!%!*#'&&#'&$#!('($$"%$()+!'('#('+"#**!+$!&+*+$'(*)"(++&&#(%''#**'*&#&('#)&!#('%#'!&$!&&)'%'%)'(%"#+%)%"**"(""+#!&$+)+"'*$$#*&'))##)#!'%&%*"*%'$$%)(*%&(*&%)&($)("*!(!$)#+*#!'(+"#)'*))&(!%'()&"!)!)%""!''(*'$&*%%*("&)#"+'#+&"'$'&!$!!&!%$))$#!&"&)')&&+#&%%&+()&'%'''**!#(&((#$&%%#(&!*!'"&#%*''
@r6758
TAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATNATGGCCCGGTTTGATATTGATACCGG
+
@00>).4F(7A+15?9/7/+%B.B=.9@>5&#+-B"#6?CCD5)+%187C<59HF4(4+>4<*8',1>5.04.')49@&9;2"A+>>;+7(G.(=@&=9(>&<%-!+*3'D4B;*ED!
@r6759
GCGACAAAAATGCCAGAGAACTGNAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCG
+
:$C"9<;)!F*>F"(;G-*AB@(%;H4@7%=C4F79'B&)2C!8()..#:3G*0CE638"(F:$$<B'C"(D$H#-=*292/+%
@r6760
CTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGAGACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCNTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTNACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACG
+
!4(48=E?6F5=2<+09#(:"(B>'6A+#)5.C11E563%<GH#*7(F%!+3:)-GE)B.F'$'(0E*:?E"13<)983H69509DHGB(;C$9'("=$A:;>713<$)"9+$*.;0GE6*G23D-(2),0D>),2H/2'E4E-CB,C?'1"'75G/$HB9,B>@1G')/A5*B4:H3+(41,AC+291+B6&0-6*G0'?A+66<4%1
@r6761
TTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGG
+
<"%&H8!>=2=D1A$@3@G4&@G):#!6.$+>*2C*'?*299>#=
@r6762
GACGCTGACGCTNNACNGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTG
+
&'(*(%*&'')'$"*%"+#$"($$$"*++#$#'(&"&'*&*&('"++'!#+*)%#((&#''
@r6763
AGTACCNACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGA
+
6%4&*CG"9*@!2E&!6&-!)6<98.?1,22C:4&2A+,696BBC>.@C>D+,*!/4C1-D+=*9@@,12)-4&8>FG
@r6764
CCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGG
+
:1)%,+,;6200E:*8%+B3@1#&=0H088(9*7.7E.E5;@E&2;A:B$7*1F6..>*A&;6=3,?<$014?012#8H(;:?:F-H$6*2.)<$'9">B3,,!15B=56.,H.
@r6765
CCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAANTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCNGACTGAATCATGGTGAANTNACGCGC
+
%0G0AFGEC!#D"=6@A#+13-.,!E"/'.<;@"'5AD6G#52B>4'''5(2C--H;G0F<5(&@9))B9=4C'@33A=(=+7C6%=*4,,.B!C9B+/7
@r6766
GACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATCTTNGTGGCGCAGGGCAACCNGATNTTCATGAACGACGNGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAANACTGTACGATAAACGGTACGC
+
+->228%*/C049DA>>>8#$;:$D&5,;%94;BC(,<6,-=CB86=)F0>&0,FAD40,)C,A)HE5($'A2;62E)H<5-;=)>H%EG=;<<44C8F=423HBD<$:"0H9D)38H,$4*+HC<&?4E5!9/4#D9$H=%4;HHF"=.>*4H8;7252",&%;=2"18*.,><3%#E+="GAG.@*H*-#!>E;:1$5FC'/B=?4#8G(3G?:=A%CH94.1+*/74E=BG?7%5A;D+"")812:(9B9)>5+(,@1A&&E7H/G:=;#5H3<"'=!E6+:D<%0H;H8=6%<=3-+>E('G+
@r6767
ANAAAAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGNGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGNACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACNGGAACTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGC
+
*!)$!)+*$'&*'&()#(%'$#+**!)#+))#&+!*+')%&))&"#&(&)*(+##&')(*%!''(*)+"$+"++)%(&)('$!"'((#)&$+'*(!*$*#&)#'(#%$&%&!(*#$!(+(%!'''"'*)+%'!+)!&(#!!'&'!)"%&%'"#'!)+$!(%!)))'#%"('%$)#++"%"$!%'"!$**("&&!+$+#)%&!!&$''*!"&%!'%")+"")!%$(*###(&*#(&(+
@r6768
ACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCC
+
,DF;C'6'&7A6$%=06$>>*7"!'>!BC7$!=4E%$E4F6<AC-
@r6769
GCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGAT
+
H#+BF-:6<F:*@:9;&!@>:.#9,;31150=A>5#F4#??-+1""6F'*0A5D0-$>80+"GA%1&
@r6770
ANTNNTATTNANNNTATTTTTCACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATC
+
("()'"(*(##$!&+("++#!+*"(#"''++*+$&))')%#(!%%&#''&##*(&($)%'+""+(*!%%(#!)'"###$!"*$#*(!++))+$#+#&)**)
@r6771
TNTGCGCTCANCACAACACGCAGCANACTGACCCGNGACGACCATTTTGCGCAGGTCACCTTTATCT
+
(!*'%'(!"%$%!*+))"'$%&&&#$#''#*$!&&+&+)+!%!'))"&$'&&!$$!(%)*!%$!%%#
@r6772
GTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTAT
+
'*H77H<<:C2@D1#C4*@!26-?*$EG5*%FE>9BC4%H.-FC;@66A,4C8A7*(*/%+C!1AF2;H3!B#,21"?-?".98%!29/5)")+->1:H&(C'"E+"
@r6773
GCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGNTGGTCACTTCGACGTATCGTCTG
+
)-#)<HH7<$''B>5*6.;29($))B+!.EC),",67$661)!21A4;G0C@G4.D!',;1(E)*,+<,0931E"'*!B8+E5D.D+@&=H*C=$@:EA##"<1$>34'F"5A@6"3%@9>,>$2D+>G5&@C#:57?+=*:''
@r6774
GATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTNACTGGCTTTGATGAGCATGGTGAAAAATGCGATATCGG
+
9A5<6@;-'',C9%&$20>B5=-&$>3$E0/G1#(&.+!61#"!3>/0256E/3:D'H%A&9#?7-+D>57+(+23'=#-
@r6775
AGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTNTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACCGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACA
+
?#12A*;,<9@?;53)"==13%/D4B!*22280)%C)-116C@#519'A-D'G+4/"?5*&4.%.5+9&;A&355/>,<->2+$2/,+E/F2%)H=8.'FA)?FC;1@':6F8F<44(-/<'H4"17%<G*1/+,C6*3,2<@
@r6776
TGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCA
+
4."58-)#E5987-9D&+)*,9E<C?6$D->+<>2C*&:476"#
@r6777
GGCCCCGCGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACT
+
*3H<+4G4H1B-C*%C!E+CFF>/&&$A#<C:6&3CE))"6D>/:5:&27-(A)A:D1@1H!)18?&*8H#0F/9&>2!B@."4!*(%-$:;(>334>(,):)H
@r6778
CTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATGATCG
+
#3+*%4'E#).D.8*%G+!C4.<:%#&3=%50=.5$#@=DDHG/@#-$<6"4/(A9+6:HC&5C;(@84%5HEFF*#%6E*368>/%872</F9C!G2;$<5=4054'(H&9/<7A'3E30FE14G4;-491E8&#B@.@"!&?2,7=0:<A+)A34-5:&3-71,F=;0;0+@)(2#D;E$G%9B=:&9
@r6779
CGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATG
+
/H":;H*#"04/7.9.2%=787!D-8F))4DD6-29?F:=4;C+7<6?7*#&B2+8%B.H!-G8C*GG%(47'C&&3A43AF?=G#H@E(-35<8G!%E5H"0%:%FE("4H?9-4)?0#,2,)<&(93"/C>#1H(?"1>D-B%F#,A(EF);->87&G6H-#0)C3G0,=F<0D(G"/-G%7E@+8D+13.-.,!,5$68H2$7/CG92@'=)E%,<3;0!;D$%5856!,(-2&&8@F.*#>CEBA4A%"3<B"7(4,A+.(.*29-'.8&3D1F>1$'31>+6<32@.0#4$.#2)&F
@r6780
ATNCGGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGT
+
"&*(!&()++"&!)+"%!(("##'%#+##""$))#)#%%**$)&)
@r6781
TATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAAT
+
.$.D>3;?@8E9<9E$C&6GD$EF66;*)D@@5)%-%,GG>+1%@(6+)+D=F%E$20E,E:<9>*G-':5(H*!&G
@r6782
TGANGCCNGGCGTTACAGCATGGATGTGGAGTACGNTCANTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGC
+
(D$(,3)>F<1&;:A77D</=:('B(<'&1:E67-H<?!#B+0,@!45EB1<#G01C,6<!&#*)@6C%6;&D=9(?76B2ABD5+5<H:"(:D=?8&5&-G9D(3F/H)>FDC3"(-#="4"6=A0=(D*-$HF'6C>$2$,9)%,-:.+/H?BD/A.A/B0/**4++"H@@'!/
@r6783
TCTGCTGGATATGCNCTTTTCCGGGCTGACGTACACCGTGNTNAGCCTGTTTTTCAGCGATCCGGATATGCATCCG
+
E"=&0B&4!2$,E@3F@D!5D.)39%/,B6H/5229=?$,('0!$B#-<CAE-+5A?4(@E"E,-/!C$,-/0<->
@r6784
CATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCT
+
+*(&+))*)*#%)$''!*#(&&%&#$#'%'%"&*%&*&))*
@r6785
ANTCATGCTTTTATCGCGCGGAATGGGTGTGGTAAAACNACAATTTNGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCT
+
'%%+)'')(+%&+()!!+*#+*$!*&!&$+$"+((*"''##+"#''%!"*+*('+&&"'%)(!&&%%)#$%)')%#'*+)(!*)'!#$+'+%!&')#)!!)'$'")"$$*"%&#'#'+#&&')"!&+!&#(*"+!'"$%*&'%)#*"'$+)$*'!$+)$'$#*)%'"#!'$&)')!+!'*!$(
@r6786
GGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTC
+
H!$'%7#.'3@2(30:"1,9#3*9*C41(BG69AF&)"B=H@D&@24&22!47B$1H
@r6787
TGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGNCGTACTCGGGGATG
+
?2BA#3:E$$D@:5&5'C@1DEFB*?C8H('&5>F*E3!/<<E>%F$A2"5CB"5"4.8616
@r6788
ACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAAT
+
47#.F21/(8-E!<)$(/.<3*>36*.DF@F)+.+($C9.%2A1)2,G"G/'46"CB>*0:8(8
@r6789
ATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTNAACCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGA
+
=(,E<6H.4A?=799-FE0)@B='3//E%(2!"'>EA@'"(4/($@*/1D;6=:'B%4!20?,-!A<:*)32:6#CC5G!.>7??"*,+%8672&=+=*@F9)&3$=#7AB"&DB8EF4/:.G285D1%4>D"<C7+3!B4?*3)=0,A!)GGA4#>#8=)E"1@B"!2GE<9.;7B8!088
@r6790
TAGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAANTAAGCACTTTTTCATTAATAGATAAAA
+
E@<*E5B-5,1)!/B"-'CD/%;?C25",7.1(F165$0.##CA7/,'C.(D0$C6$&83/*539#5,<8!35B!5/-(&F):EC4
@r6791
AAATGTTAGAAATAATTTCATTACTCACNTCCCCACTTTTTTGCAGAAAGAACAACAAT
+
%70(@,>%5<A@":%6,$"5/BB8B=9H"3@#*,:-F,).'<F@=@F<1,>0';;"%/.
@r6792
NCTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTAAGCCGTCTGCAGGTTTAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGNAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCCCACTCTCAATGGTGGCG
+
&')+#$(+''$(*)"'!#%*(*#%("(&#"')&&(!)("%#&!'&$+!''"%#%#'+"#*)("$$)&#!&%#*+&+"('%*)%*"+#(++"$'!#)(+')$(!++$"%(#!*(+$"'*!*%!$"(&*'""%&+*&+(%&*#%*(#!*+"('!+%#(+""(++#(')$$#*"'!!+'#"!+)"'&&#&+'&'%'"'$(""+*%'(+)*+%$%!%$$#$"($+$'$$+"$)$!(
@r6793
TCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGAT
+
(8'8#'%98)G))*?-#F<C+.*G%5H-6262G*G4A-#.E/GA+-0%)16$5.;B%99G=:,C
@r6794
TNCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCNTC
+
%+&C1=CH*';7#=/,@02@*"!*:2:@8*-%A7;"E(!%#4&8/.D?.F89?A:G#?%%F?1&CCE3HGD+.46BD
@r6795
CGAATAGCTCGATGCACGAGGAAGAAGATGNTNGCTAAACCAGCGCGAAGACGATGTANAAACGATGAATGCCGNGAATGGNTTCACCCTGCATTCGCTAATCAGTNGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAG
+
&+*%+("%(#!()'!&"(%+$())"(#*%+%)*+"!!+(!+'(&+#'%%"%&%%*)&$!*)(&"&&%"%'#&'+!&$$+!+(!+))()('#&$#+&#$(+#($$%)$#"$*(*$)%(&#"+#!%('+*$%&(+&""!+&*"(!$'!"%!%$#!"$
@r6796
ACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACC
+
85",@%>(33FB7+D,F97+6+@4&E/H+&C7>>"(8C5-E-)-;"'197-2672<#B@-./*B-%4@=0G649E
@r6797
GATGATGTATTTTTTGATGTTTGACATCTGTACATATCCGCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTACCAATAAT
+
"E3!8-"F"1;9)%@0::!%>B'5"0D#HA)E5H!D?B?CF$;!*?@GG*(:34C#/H'F'5<+:9?A12.4C(5?;5*3:"8C%9-*&:!"
@r6798
CGANCGCCGCAATTACNGACATGCAGATGCGTCAGCGTGATGTTGCTGCCCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATG
+
)(**'&(')"+!*##$!#+))$#!")!#+*')$*#+"**&#)&)#%*"(($#!""#*%')&%'"&#$!#%%'"%%!*$+*#$(+(+)##)&)&'%!(+'&!(
@r6799
CATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCAGAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTANGACGCCTGCGGCGCGAAAGGACAA
+
>/@AF36/D5?:6:3A/<:3").=0.B8@C%F>A/>(5/(E!<3>*<G.D/FG3,&1&(%1&44?B/C9;)("9.-,461&9C?.&$)25H,6-:2*H;7=:>*3"5*?8,)(%-5>,1=+9&5A?'7@:H'1!F7'7-&
@r6800
NCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACNTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATTTGACG
+
!=$2>=';=2&;,FH9.&?8=9/;/C8+?,-79#EC.3*0<5=2>:%4;$A/0$,H/5=8;052D0+?8@/1%77-'6??0H/1+3"B1#7-50#"4DF1?4&44@<B
@r6801
ATATTTTGACCCTGAATTATTTCGCTTGAATTNGAATCAATTCCTCCANACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTAT
+
1F0*2G,$3-?(/D$@5A='3A#4HH/A@$(H6#7-H..+(9)=#+6;"6EGE%5.8+!&&01''>%@.=*'9+;'D=:7(%?0E2("6H#8A(=3:##
@r6802
CGAAACAGTTCGCAGGTGATAGTTAGAGCCTGCATANCGGTTTCGGGATTTTTTATATCTGCACNACAGGTAAGAGCATTGAGTCGATAATCGTGAAGNGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAACTGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACCGAGCCGTAGCCA
+
:,F3)HDE>-(A/E$870;6/EF@42F!&<<;.)E/</-'*2C4-1B'/!/FBG7C-."C'296!D@B1(G?-((@D+%?"4)0+0A?0#@FD7D8889(G;?B.GB9ED+=4+$H.(G'(B;091<"'#E,&C-/:,6EA<#%+C9(*=+@H@6G*(H94#C4B5,95B.3"'((;+/":%,>&'(C-#)-<"7C$@$@9114D==G$@>/E7=#5D9&56FF,%3F;&@&D>$
@r6803
TTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTNTT
+
D;0C*).CF("8,EA@#-/;*)@6D@&(8+%CEE3F$*%G2CH'5*0#'01)E65.8<H"3FG?*F0D*4E>,C!C:>)0"14F.)<101GC.947B0"#%47"(0B5?FHB"(4;#G48,A!A6!?<4A@
@r6804
TATGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGG
+
$&G???+A6'+AGDE=#,5(9A<G%/35!@,!5,E<>?'#&DBB.)6==F;&;G%6..</6F
@r6805
CAGTGCCCGGATGNCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGNGCGCCATG
+
7!@4(<77-E1":C:G+7"3"A&06$:AA).#$<;754GC1-."#-=8;"G%3-.(:'*7<0)/*D3+F=-4)72@1E$CE+%>F<730@@;'3
@r6806
TANCATGGGCAAATNNTNGTTAANTNNNNCACNGNNGGAGNNG
+
$"$$#$""$!#$$""!$#!##"$!""!#$""#$#"#!""#!!"
@r6807
GTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCC
+
C+&,=-"0(1F5)'D'+!E69@"$CG%1"&C7D!46@(=H*C
@r6808
TNCNCANCCATGCTGTAACGCCCGGCTTCATCCGGANTCTCTGAGC
+
*!""))%+(#%*$)&*&$((((*#%#!''+'%$!#)*""!!)&#'#
@r6809
CGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTC
+
):BC.C(&7GH?/5B#+E9>07$@%AF#9$(<>''#78G&9'&85*(<8FB2:3$<!DE.=62;$4?@<>4<12%D'?E.>)H547)E#GC'?E,%1)!??!>H--=*>:<DA2.)6EA7%!6/0+),&?G&:<3=5&<89@8=!
@r6810
AATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATT
+
.0:$4.,.8;+'-H=+=@:D?,9CEF-&CDH>9)1@*@*)*%"9B%&@9?G(,9#2:'H66),)&4?H'6=;)#@D7:5?
@r6811
NNGAAAGNTANGTNNGNTCAGGGNNGTCNTTNCTTTATNTNTNCNCNNNTANANTCANTNNNGTNNGNNNNTAGNTACNNCGATGANTNANGACANATTACGGGNNNTTNCNNNNNTTNGTNCGNGNTNNCNCCNNNTNNANANNACAN
+
"$#$"$$!!$##!"!$$"#$$##!#!#$!#$$$!$!###!!$"!!!!"#$!#$!#$#!"!!$$$!#$#!!"!##$$$"###"#"$"$#!$#!$#$$$##!!!#"$!!"#"$"!"!$!"#$$##$"$""""$!###!!##!$!"!$"""$
@r6812
TTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCTCAGCCGGACCGGCGCTGCGGGTAAGACGCGGCAATTTCACCA
+
AB@@=%--F!+@0(BF/50?-BA;D!>84<;HE+67?HF0(>B/"7@**9,><CB<$%524G,>D7*2/#<A'@"95D()!6C5D,
@r6813
CAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGT
+
%;>-9A'-D/,2?43-5)8,*E$H/?GC+F?*B".<2?'5+1(3E!F
@r6814
CACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTC
+
!+'+#!#'"(("#"%#!+'$%!+*#'#)!&)#""!*$%($("($"%)("$'"'($&%*+(+"!(&$'&"
@r6815
AACGCCTCTGCCCGTTACCCGAAAAACTGGGTGNCCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGNGCCATTTGTTTCTCT
+
9<&GB'E5+>:/*H%<!&F'1=-9'3@DC*-=3D*;A*;126G62+;82&!.6*"9/D*%B)=4@?AD:5,;9$D)D%95C4D,(4:;&)<44#?-&!8@8%&;,.C@=@*@@%#D>$;.!C7.8F,H3#'*5;B8F>@7A'B=;DE:H1C2742+6=6'G>
@r6816
CTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCC
+
6/(/)E/!,H8%!%E:1'B60"CCC.E/?+'5<-"$)=9*E<#$G#88(!,#(?H!$#*((+)<H<<"3,6%D%B%!"/99/6H
@r6817
AATAANACTAAACTCCAACTTATAGTAACCCTTGATTTTATTAAAATAANCGCAATTTATTTGGCGGCAACACAGGATC
+
&<*)41E0'=>28@8*,"H&F3?++.2@E".@@7AH).E/,3%HAA7:)$D)"2-FCH.'GC=HB52<H)A.D6$'%=H
@r6818
NCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCNGGAGGACGCTTCCTGAGCNGACGATGCAGCCTGT
+
!8G&/$>C$2-E6#7E%$4-6.H5GA!%-0"&/D?3>=13G7(,??E!A6G/('+E?$?#</26-((5::$9,,!E.6.%!>>3GE8<=*B0F.%(D7*4%@'E7+E0/59-E>8,A?&/D:>"%,"9#?5=2<<#C2(874.D779B/&"2&(-39-$!D
@r6819
CCNCANAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTT
+
$'!)($*+'#(&)#*('%("()+(+"+&&!'*)+$)"!)*&+'#')"'+())%&&'&+!(!"
@r6820
GCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGAT
+
F48-)13&EF"-7/7:F$3AE"6"G8DH0!;/3H2*/C2BF-D:/,$!=$D=)9,F$D,):
@r6821
GGGTGGCAACAGTACAGAAANACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAG
+
=G)>F"HF==#$2#7!7,C6>H&8+$?;9*!E'DE#6B6D&:CB,'=1B42(%5.9@B$;4"HH&/;01%<'F#$B/2H/;E4.51(BFG
@r6822
GATTGCAATNCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGATCGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGT
+
5GG"GB,4(*2>?)+E-"5&>8#H4#+;8BCD=&0B=BH85&@FCE=%7A2./14@!?-/)8;-*GE46)GE?(BCD,F==2:7/E@%D;$):?A1&190.>6;?9;%#+21!-4
@r6823
NTGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTATTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACT
+
%%C<F0'&").)FC<;-;09;G>'AE7@29::/>8="$%>3=%24G7B.F@#>-((H)0;"(1B(:,G;(B42@?/1=52"0#<A7;.C*-#9"E#<8A:@B,/5H7G2!(.4CDB6?'8",@D"=D*#C18-1?D,!:B9"71GE:@5+1#D#-CCE"A((
@r6824
AGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACNCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCATAAGGAAGCAGAAAGCTAA
+
0#A8%(A,:?,E81F)+!64H/'F;G;0:.3H4+B/&'$'8&@5:9F);8<?=6C=@%F--,45$@)(/DD(8=$!180.-!76-("4+)C#5;H<@/'$969$=64EC@E8?GH//'!8'6HG3;FCBF15A:8:&4.?#)!:D6$(4H#)?A>G!&$&F6749&<>!:28>3B%68F
@r6825
AAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAG
+
G!5F5!@B",-H;/2<>+(?D3F412#!'D.GD(7<(#4#FG%C+";-?#C6:/C:C:27!=99H68<.+B:#FF@5(=%,&.";EFG$;E<=8/>8;/=?66=>,"87B0B0(!2''#.=692+.#%G.69@0"
@r6826
AACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGAT
+
"/?+=&#>0@A!+73<58@"H;.A&00/88!.1C<#05A@H:G1C=DECF66&<.+/"3.3D/.#.HC-7)19097@G#
@r6827
AATNTCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATNTGTTCTGCCATGCGCTCCTGACACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATC
+
*%&$+*%#(+'(#(+($))(#$$*#%)+&%!%+))&+&%&#+*#("!($!+*&+"((#"**##%)(+)++*&('%!#$+*&%!'$%!&')%##+$"$+)*%&#+""+)*&"!$*%&"$!#'%*%%&#'*(%+$"$)!"%
@r6828
GGTGGTTTTGCCCTGAATGGTGATGTCTTTTTCCGTCACCCAGCCACCG
+
1A5:8"8&GE!@<(*)C4-4/'CC:(HC9-E7HDG@0A=1=CAB/-D7C
@r6829
AGGTTGACTTAAATCGACCAGTAACAGGTTGCCTTTTGAAGAGGATCAGNAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCC
+
%:5!D)E6A;!'5(:!>@!%4#B*D47-9A2F/C'#.F+;7A+':0&9687*+F%6:F'+;$17/E/0H83!,BA3%/AH85HG4D#,.4:
@r6830
GANCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTAG
+
'F/,!2&D,6B!7$#2648)!3''D,F(E;:9>)BCH!'@+9+?<A*-,A+?)++66/A8#=:9-#
@r6831
TGACTCAACGAGGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAANAGGCGGCGCTTACAACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCNGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGNGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGA
+
?;$(.6*"75E"DFE@**):6$AG(-#G4&0+<9!@-2,)(#30*C5-BC$2%'$%=:*FD:6C%<(H->9.423>13H,E6/4G+'%F//F)'*F54(#=F#/-2>:&H'@3DG:4#%>?(2+E6-G?=$$*8-.</50*<%)&;!-;@83A#&B;G,E!%2@5G?%A#9D'3#9+;<:&-H#80E"<0G#6@6()DA"*6?6;@@HF;<:!AH&3%%.4".<6:E.."@7%62G(()942+;
@r6832
AAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATNCAGCCAANCTTGCAGAAACGACTTTTTTAAAGGNCGGTTATCACATTCAA
+
+#')#&($*&'%%#"!)*#!"%'#'*)'$+%(#%("&$)'*!$*()%)#+$&)%*&%&*"%%++*('%#+$)(#+!+&!*"$'*"&&&*$!""%##+"+'+)&)%**(+'$(%$!&
@r6833
TAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGCCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTNAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGT
+
*2,HH6'>D>*/+A4/4+!9".@%)#@!!C8/=9?6$'<4&"'+F.>?''27E/+2-=)8,7$+8#9BCE%!*)*>$0#,#2D00.9(?0('B7(7-%.*'+7?'#9;%@?%;#H2'(!C>)>D3.8A$B,H;/9<-?$F#$'B>&:8-AA-4E#G6&?'BE&,8?$96D0!<9F##D
@r6834
ACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAANTCAGCTTACATGGGCCANGTGCAGTACAGCATGTGGGTGACGCNAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATGGGTTTTGTATTTGGCGAGCAATGNCGATGACGCATCCTCACGANAATATCCGGTTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCAGCCTTTCTGTTATCCGAAATTTCTGCGGTCAGGTGCTGCACCGCTNGCGGCGTGANACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGT
+
:*A3.)+'),;!155%=3EA,@0?7;,!=D3'5&88C$A@#@1$14(<22<B75>5:%EB,G8GA91H7F8@")6@=/G1A*G8$B73=5@*E/$-)-.'/<:?*'#2D77$'A'"8E4$8/D*@6H>F-1:@;A=+@?C.=9#GE5E()?7;%17D%>2D1)173GE@CAB4C9(8(G.G%%9#?,8;6C#%C)G07F/8>/B>'36%)-=0**G*E*..+$#$B!"F).=3%",.'-4A)*"?.F3G4543C4*73%H$G-7D/,AC8!=?B4C2(7'EA)8/%E9B>:G#.C3(A5H>BD4ACA1!@0D<1-(C:4GH<=3H1)&AA-2%"CA!6'-2:(<&!'"::5((97$5.B2A1+H#81$.'=8#3<"56@/$.-='65.7C3::G"/"-03<.!-5C,;<H?*B'78D?48*=;,%/C(91A9.(H/82=+(7:A6$22E;:3#%545*0E76?/=.&HB@@=2
@r6835
TCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCT
+
:2,1DH.@0)2?5:?B=D8>)%9+?6@=>3>7@<&+E(2/,;(502/(.$;B<,&%F:E+&6@-;FC9CG.*,=(C9A0(!%:/>'8=B#?E6+(<;,EG".D7.363B?5?-@G,/>'5+2!B5!)G=!;'</+;>('-=0$.3H14)-$2AC4!*AGE-=?00E0)@'G8:.!96/77>.
@r6836
ATCAACTGGCTTTCCAAACTCGTATTCGTAAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGNTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAANCGCCCACNGAGATAAGCAGGTCTTTTTTGTTGTNGAATCCAATCGTATCCAGTTTG
+
%37@9>3H-1D;$-0!=><<-0B*0>BA6+=<,(.>@E78,/0-:H,G9,*@!)7G,).,"?E>(?:B8-"G#:).,4:<G9-A$'3BB07::>/>:G&G=)8(6*'D3:,%24GH+%44(9@4,:A4$;0=55!!>AD!DH*BHAF>?*1,<B8.8,A)=:<$>C2&2G75+/B2A*$/+;'2.7=91<8=2-=@;5BA99EE*:9,1%;./#14:((%965A,:@*,1?"6?AD;01#/=9=/D"GBE7(D71+6.)'>H:&;+HB-C!CH'F7>/A5<#*%-?,C,"HHA*#G$-,H6C'@G-!"<%"AA&D926#$>=8@>+<0$>,16?!065F:+6+(*'(*D-?G#&*#F.,9AD/C>;,4D.@*
@r6837
GCTGAACGCCAGCGGTGTNGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGT
+
*->9$9)6G%+#A4B3'D''2"8)G'B=@)0%2'4;8E7H/4!$-#7B2/0A:&2..-:+>/=!
@r6838
NCCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTT
+
$67/?E"*8&:6A9@7+-#CHG9+/0#C;&-CFHE4,B:2CD&)/8H>?C03(=+/5*BH>)&F7@F7E+?)'E8@,.7%%0.A':@@AE*>6A&2-:-@;E78<C1E5!A*$DF.'>H635+@6H
@r6839
GCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAG
+
H<#!;.A6+>#'F::8(*D"",>C----!0=<'G)"?G=.CCA9G//?
@r6840
CTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAA
+
90D$!62@:G7!>=(4!2C7""3*:;@E!/=;+BH>'4/;8*'9
@r6841
NGTTNGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCNTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTC
+
6B@9C.2E9B/F2H.2.1@C,C44G&F1799>$&1,:/A$;+1=9*>7"4A39='!0*1%'A=<CHA>*%*32A7GC01,9=."8:3,F1BG$F;*-=8)CH;@9+FF96FB0;C*.92@0;H!8?8/:*$#.>>9$F;+()8F)*+0F<F>?%,6>")%&66&D&F*.;$=#E=HE+2
@r6842
TTACCTGTTGGGCAGATATAAAAAATCCCGAAACCGTTATGCAG
+
(AC379)C/D5(0":?A&,54/A,=0E:B$&CB;G2@9>5H7(5
@r6843
GCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCNGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTG
+
+)*)(*&"$)!())*(&%(*%)((&%)+)$&+#"(#!!#++(**%)$!!)*"##&%$&#*"*'%(+$&!"(&#(*!)!'*""+&("%#"#%!"#$")#$&&!+!!%&**(%$)"#
@r6844
TTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGNTCTCGGCATCACCATCCGTCGGCAACCANATAAGGGTGTTGCGCTGCTTATG
+
2<@=0=?%.**E6<F>1*-..+>6<G9!C$)*<EH04D2"0!65ECAA/F:#;6AH.'H)D11.?;&*)'?6G0%9H03&?2#?B?E9@51;8DG3!/.$4?:2/1;+5%H76+'H/0+*=G+-=9"31=$
@r6845
ACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTT
+
<(--/4@%G@#.,$'9*/?F==FE(-':,:'7FH0%.-7246"0H#39B)/?+9>H6;6E(=-
@r6846
AGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAA
+
8<H#"0/99/04$59F:G2=))G;77"5C'9),3<5FG&"H04;*"G:,
@r6847
CCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCNGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTT
+
81&,-=%,4(C$*E89<9F*B/3"&9+&-0;!H@!#!-8#!B=6#;:>%);G.EH%8)5>B>C"+D>'H.
@r6848
CTGCCTCTTTCTNTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTG
+
62.B<%5-5>E;+-:&2A,$.DF98.B+85<B%-1H%5>7?A)+C@;7'99!
@r6849
TCTCTCACNCCNAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGNGCCACGGGTGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAG
+
$&)!)"'$$(*"++%!%(&*$#++##+%$*'!#($!"*%)#%"&&"#&$+"!%#)#)$($%'(&$))#!+"!%+!&+'%+%!('"%)&$%"$($($'(+%)*#%(#$)+((+$&)$((+"#+(''+*"#'+)$)#+#%'#((+)%$("##+"&&"*!%'%$%!(()&&*%*($"*')#"((&(")&*''+
@r6850
TGAATACCGACTCAATAAACACGGCTCTGTATTAAATNCTGTATTAATCATGCTGGCGCAACATGCTCTGCT
+
%)*&-54&82!-@0H/"0>H+E0%G@@!E#<%<E'27+'1"$D"5@<C4.HGF!49?.'E(/.%"&'%$3<+
@r6851
ATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATC
+
242#%0%=22B,?B!;"G#5;%BH-"C(GGG?8+.+0//$/B9->/H!A>)G"-+"-
@r6852
TTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGNCACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCC
+
9?<H(+<-7*60=G8@E$A-A@'<E/%60=8@'A#=244*+)->5'%>!+?B)3&&(->9#C$#5-B"+>3CC+1,1C=*-<F$8C67GD&E<F@5FC,)*D8F78E)G"#4G95=G9C=1E0;<'*0)6;=5%=CG2,<?=:1.379-)'84A>/F!:>EG5?07"&&)5F1G;7-)/".!4G*C=0&8(2HED0!D?,C&<(A!B">'G;1*-E$0C,E2BC"3B/+!3F9D@:A?.4DF2>(D267HG4.$,/1BBA<$9/9=>#$1A
@r6853
ATTGCCATGGTACAGGCCGTGCGGTTGATANTGCCAAAACAGAGCTGTGGGGNAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGCCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCG
+
D7.C438A(0?"2/D07$>02-'"&/92./)HG$(,AD!6-#,@.G3>/-!?01$)2E+>'=*)+1:D$;@'$91"GC%.(@-%@#82@0!21C+.;>A93'8C;%@BA%*"@2:++,H8*$/F"17
@r6854
GAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCG
+
0G:CHF<)"&=1((-B&C7%G5(FC1@%-@30'HA06/,DC"#"335-5&H+G"@GG@#AD,$
@r6855
GTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTG
+
>;)<F*C'FH4EBC>A972!%>+'B8"/,#><2C&C519$6G"2(2*16B>A.&EC,"H6"B>)/:?D#)=@9'!1%75ACE1"80-*?$:+(/:2)$1C,:<HH-E+'AGA(2)9C)!EG5%!0&1C=#D&5"'H(*;)@,0>0:7#'@1-59(?EB7E0;%%54/$>#(.@A-!A/)<)#:#G0+8B@',&.1,8DHC04!H=;3=C#6433!&741C-$"<)4;?+:!7+/@F:/00*4,@+B:C5(9:0%@&,<H/8A59939GD?
@r6856
CGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCA
+
C,-97F*=B9@@%("@2*7:5;?1"3<&/H&GCB+3,5FB(C6FF9360!7)G0A.ABH&4C7>$;-C<D>BA4!
@r6857
CATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTC
+
G:E3-&7C/,5,/>//7%>98?&64:"@B;<7@%722<@15+5E<H4)>(AD,("%;,6D$
@r6858
TCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAG
+
9226E1(;B1F>D--)@)%DDD:?""C4)9:'<B-EH&?(G/F&9A-$#
@r6859
GAGTAGAAGATGGTAGAAATCAAAAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGG
+
G;4-@->;9A>+6D"#C?6&77.4EBFG.H4G!5A;'"A790>+H1@<E)B!")0"'D?**F&?EA<+!?<6BC%$-#;CB->(G4AB-9629:0#061F:%5G<$E0(<HG+%#,:9A->$
@r6860
GCNACNGCAGGGNNCTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGNCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGAT
+
'*$('$'%("*!"!+$")')($("$##)!)&%#'))+&#%)+%+*!()*+'#'+'(!'+%+++(!!$'#*#&"(++'$&!#+(!#($$!&&##%'+'#(%#!'"))%$$%$$&')+%#(%*%$#&'&%&&+"
@r6861
CAATTGTGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATC
+
!*F.(2)1/-,.@)6039F7'E!!C61&;1G?&%A3.#7G:H8G,.A20F8
@r6862
ACAGGTAAGAGCNTTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTNTCCGTTGTGCTGAATTAAGCGAATACCGG
+
;90/*95B8%4,68F3)0?8"367&CH&6?2AH;-:9+-'GGA2D@5H:>HC?>!HD70.G=9$77H=?($?H+EE6>C8@=<6'.A&F5//
@r6863
TGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTNGCTGCATCGACNGTTTTCTTCTGCCTAATTCCNGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCG
+
'+)*#$(!!)*$'#%'$&&&!+%$"&'*%(*$('!+#!#)%!')#(*&"'+('%#"("(!")!&#(&*((*#++&$'("!&($(($%!$*"#$'+%"('(')#!+**%''+'$""#+"*
@r6864
CCTNGCGTCNCGACNAGCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTNAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGAT
+
"!%"&%$&$$"')*(&!%#+)"+#!)#%$&&&##'$$"%"!&&"&&+)+#&"(''#$$$)$*%%%&%)*%+(!*#%$$*+)"!+##"$#"(+$
@r6865
CAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCA
+
4/$,7#=4>:.G%7)>7-4'(=HE$B)'+>,4&0;,@7.E0"B3,B#$&<7(=?-@4DA@6DE?H-E3E7?/2::;0H1+"$1$15%C)"&D<4H4HB(!B'(2!(CF<5.';2GD-E.62%A4:B"2.%8DH%5.'<,(1D"*&?'*E#*(/=4)53BB.B%FE%+@!<>$-'5+81)3@<$+,+0/G$$H);!<F4+A17@14D174"-1,)<+4!3&22,:#EAE$D3<0!-C94F!1&H:B/B,D>,A14#.8E3B
@r6866
CGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCG
+
BA-7,!;B=8(":49$0,%,F5D"'&G,:'H&@<';?5>96#*.?6E7E&>F5B.
@r6867
NGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGAC
+
#:6?7?=+G,??:*)4-/6D=%#"C'D$/G%$E7*6@";D=%<G,
@r6868
TGTGNNAGGGANGTCAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTT
+
($*&)%(&''&#(#%(+(%%+))%#%"&"&)(($$!!)%"$"*"%""'+
@r6869
ACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTANCCGCATCGGGCAGGAAG
+
H96=+C0(-(7!9;1&C8A,&8:5B/:8GDC#+-(@H6-,522=>2B1E16066.H8H:3
@r6870
CGACGCATTNCGNCCANTTCGTTCTGGTNACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTAC
+
*')$'&*(##(%!$'%!&%+&**&'**+&!%'#)+%!'!"%!&)(+&$)%"!!)!'+++%$!#")'##!#))(!&+"*'!')"!+%*(#&**)+$'&'&*$&&**%#
@r6871
GNNTNNACNGNCTNCANTGNTGCTTTCCGNTCCNGTTAAAGNGNATNTNTNGNTNNAACCAGNGNANNNNNNCANNGGTTACGANCNNNGCCNGNGNANCAAGTNNCNTCTNNNNNNCNNCNANNA
+
!!#####$!#$"$"$$$$$!$#$!####!###$$!#$$#$$!!##$$"##""$$!"$#$$##"#!$"!"##$"$#$$###!!#$#""!!"$#!$#!""!###$!!##!###"!!$!#!$$#!$"!$
@r6872
GAANGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCG
+
A+'9ED/?8/9<*),0"!HH!AG%22:$6D;@A82;)%@72552:*'5FA/4:6EG"!D8'.)'=42A55BG<-&>&6F?E<%'/B>=?+7E7%(19DH"#CA;.5*4H
@r6873
NGNNGTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCG
+
"'#"$++"$)&!$"$"##$(%)&++*!*%!!(%))(%()$%'%)
@r6874
CCAAACAATGCCCCCCTGCAAAAAATAAANTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACC
+
+%)%AC15=&@<C?&.8/2AA%=>B&/$&7A.36@#?>*C*G#D'')$$F(&57GC3<=$C"EB@.(>@7??&0F71=&*<A$'C'G:1)"<:&$'#B2A+"F)!F=32/C>+*).A3$3*%3,F1,C#=<933=H8C4A9%3
@r6875
GCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTG
+
8&:A8$,:G?4)'64:&@;+-==#H>)(*A4:4+$19-%A3&?)*
@r6876
TGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGNCGGCGCATCCGCGTCAGG
+
6F;":-+/)?1!8>*.-%9/$B>!81!0(>4!'C+.DA)/*>A9HBB5(20E71/3?H'#
@r6877
AACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTC
+
#=H@1C$-2@>,%**?=(#$FG9%*-2?)=&:**>:%D!<G-94.HC3G'-EA?$2B$5D.<
@r6878
NAAACTANTGACTTTTCGCCAACGACATCTACTAANCTTGAGATAGTAAATAAAACAATTGCATGTCCANAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTNTGGTTCANTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTT
+
,#C>A;%--08!88-.8>#&(G)D!=!#'9D$G((?$7F#-4?@H@<'+/&*+>%)("C$)#>;'&"@B5-(3-FD'6!/EE""<$;$4F:G,">91F0+:833G7B(::=.AEF='C<4&.#C#"B"DG-G4%5@5A!#16*76#$"8'/=2)#!$;1<;?F=6"?B61>$(.!@%./0%$"=.:=A(9-@%(;>(</2*70#%9E4!=+0-.:%E(G4/*7;6,*>;>:
@r6879
CAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCNCAAGGNGATTTTTGTCTTCTTGCGCTAATTTTGTGTCA
+
6+A=7,#14G"#FHE--<HDA(4)*!@(H/GE.4:322.(420H8.$5.!-9=F-7$-B')<D*@;F)1C4?8.F>>>>:9G
@r6880
CTGCCATAGATTATAGCNAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCNTTTGTAATAAACTCNATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGC
+
62)2#7),<.(#@3>$$>)3B(A:B==4B?)>@42="1G$.E<>*(B787E0,C6="+,(#H4.>'7F*2$"%8><;-!+;FG=../0?$5&35C+77E#H9)734D7.0;36!%":):;,0>?9:*G/&.0:"*:2C@?A8;*D/?=,6FBCA0:+)0/5@7H;HB-?G6)9$+@?;<6F,;#!#C$G"&'6#42DA$0.#@8/74:(9?C6!G;.""@")"6
@r6881
ACNAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTT
+
EAGC;BE$D-#!&+E28!ED4?7>,"$:1-@"6?053,,1#,HF&*)H"#)7
@r6882
TTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATC
+
0FH#HAF0!!,<*=E*>'>4.6EACAH>8>F%G1?>?1*;H>8$*1-9'
@r6883
GGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAN
+
#+%#'*!(!'%)$(%''++(')!!+#&*!'"*++#")&$%(!#&+$"*'&$*"#'$)()!$&"#$&+*)$%%"$*(""!)#"'#!(+(+)%+(+!(#'&%!+)'"!!
@r6884
TCAGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGANCGTACTCCACATCCATGCTGNAACGCCCGGCTTCATCCGGATTCTCTGAGCCCNCCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGCATGGT
+
")+'#%%'&$'&"$+$*'))#&$'!))'!#)&+$&($%)%$+&#"!($(*'(+(&"!!'#+'(#"*)$(%"*+$"'#!*(')"$)#+*+&'&%))!&&$"!'%!*+)+$$+&*)")##($*"$+%$#(!'*"+'!'*$)"#$&$)(**'+!("+*!%%
@r6885
GCTTNGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGA
+
-8B'*&!:#D;B?HC&=4%?*-E@=3>#:G'@/6.@;.*,D":!C5H%'*./=/;BG>DCFH?4"*6%'",+%H?(98'6/7.*?>'B
@r6886
AGGGGANNGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGNCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGNTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCG
+
*;2;'@2&/+.6G#D6,-D&'E*=@#36(3#E8',*'/DD-4<(4?'.(2<E#GG5-:<:((E-@2>A*:!99G:5HC+E1?=G&=%7?,%.>75.@*')%/7'3'=G1*&-!'=>D-#*6A2D->%59&?>647=#H$>H-9</7$:<&11##43C=545#96F+4,1(/
@r6887
AAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCA
+
%3%($-;5%+(6,3B%.:H,&#C5=G3":%EB;95-0+>BEH@2E9H1&23?+E5@%!%72?,9,;53#GB&+%1?-79,6C;8)+(!E!7G40,,:1#G("'"<40G:F#*0>5)%+("8,@%'AFG3!G$.(%H2#A@>=A=;57.@@/<)=-='77253>.:G@GBA52,
@r6888
GTACGATGNGGATGTNNNTNGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCANACATCNACTCTGCNGCGGTCAG
+
%&&#%!"*$'")%"$!$!&*+(&**%!%')+%++%)$%"%!"!(*'"")"'($&*$'&(%)'%)%)!#*')''!"#!'*'(')"")!)(#+#'*""(*$&
@r6889
CTGNCTGATTTTCTCATTTGCNCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTC
+
%:G6*=2%9#/(8H!3/.1=B-)55G$-%A&0)-9%.F=";4!.G<B%>3B2&,,-A!&E'H<#;%;&<'(6&4*F57;4G6@.E>3
@r6890
TATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAANACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTACTGGTGACTGGGCGGTAAAGCGGCAAAAAACTACC
+
D:0.;(F4+0(F,=H)7/GD&?4B4:1188)'9#69F*#=%9/&.5!#<G#*$@:1.0G?79>2.0%5637:HE$G@H$/9(21E>5*,4>&A8-G6=A6%>B*G*#'-+"#H6$)19!@8%2)@H2C$E0>''0FH1),(/&F@8<0$$:(%<21150HE
@r6891
TTTAATCATCTATATTTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATT
+
@5*#H4G-4G;<,1$=&D+"(,2B>++;/12G.705C(:-5;*G.?7*.<+/77.+&!40G;'>H"C6*#!-0=(DHDH1>H6;;C8'6,@+()'?8-)">='C;<G>E*#GEDB.=0@;DA!9>GA2=EC<()ABE0!(HG1C=)E
@r6892
CCTNCTCCCCCTGTTGCAGCAGGATCAGCTACGGACTTTGC
+
&'*&%#%))+*)&+'%!'")%+*"*%!&&%%&("*!)('(!
@r6893
TNNCTTCCGTCTCCCGGATCCGGAACAGNTTTTCTGCTACCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTC
+
)$$+%$$(!'&"(#%%'$'"&'(#'($)"#'('"(#')++!!&+$'&+%*!(#(+#%+#'$!+'&+*+)$%!'$')%(#$*+
@r6894
CGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGANTATTTCTTTAAAAATGGCAACCTGAGCCANTGGTAAAACCTTCCATGTGATACGAGG
+
2""9<CF9!*3F'A1*/?367>D()5=2F%>4%G6)>0!+&6AE7D:@5CD,@C()?G8-07CC@%$=*96D=2?B77'4:/71)(C$?$1;/6*!'24$/3C?/B?8#3
@r6895
GTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGC
+
H80*9&A5-4>,4"7A.D@=A!#9<,2&C%83(:"$"(E#F4*G$>CE'$:1#F9A-A?#4#8F/<F#;+'1<#F?GG9.DG=AF>4:=;(D.F638"5)8;F**<#3B:6'0"<)A(6/802"G;$:;G11"@C5//A4=;+%;8'-E?D)A9H9(B(?.-A:9-A,/HC4"$>D?1FDF(FB,#8G(9>5:D!@@4#)
@r6896
AAATCCGCAGGCCAGAATCAAAGTTAACCGGGGNGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATNCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAAC
+
@G%C0?$'7+1-&!<?E992+0?F'H?+1/E'."26FH4/ABF:7G"31B:$B?%EB-)'</FH;,A<,558+>?#=076<)C2<82(+0.@H;F-10,@"G;0*E?E*8A>37>?75'5%C9),"4;;/5,#@*<88G3&F#C<89>1$9/A/=.<HD&;E;><5.2?%C-+!"(#@0=11
@r6897
ATTACGGGAAAACGTAAAACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGA
+
#(%'%*$)+&(#!+#(*"'(+$'#$%)"%*'&%%)"$$*+"&$)(#+#!$$$)"#%#%#'&%'(*#'$##"*+%(#&$%"%$!!+&"+%#$"#$$
@r6898
GCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCNACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCACGT
+
.&.9@)<#D?8+/61/06+"4?G1"557C9A6=%)75E1C9D<01E;5+;A)"65((@C-385756+%("9+-?03((F7D8'D2#''$0=.6+%H@?;?*"81/D,384'-%.$%>F7-.3*-$--"&:@95/%@7;?5>?&A&5!*<?B2E+E?DF=:"/(7H3D+H(8"&/G>B#
@r6899
NACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGC
+
&&(%5?";%<A/=%=@H3(:>3<7--97+/6G:0/;&DCG/@>5&+=DC&GE/%-E;>=B.>=3"+5A*"G*@?'F,)H!&54H@$0"*9&G;1
@r6900
CTCTGCGAGCAAAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGAT
+
,9&!A1B7*A$(5@.2@6+E*G04.3$/**9/2,(E(8,-$FG;C'92.5&-=:
@r6901
GGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCT
+
;9B"F)8<HD<&9*9$8(0..+='70&>%-%DAB=;$E<C#0F$'*1$GC1872-B,8
@r6902
CTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCANTTATTCATTACCTGGGGACGCATAATAGCTTCTGTNCGCCGGACGTTGCCGCGCTAACAGGCGCAACACT
+
F)E&1F4BH@2*9;EC<(B@-++GA<&A0C0<=/'8G09B(;>82))AG(/B,,FB'H'67&G(B&'1((D2::%,.<>*AH(&F/:DA'7!;@@7&8B<57!?@4689?9BD+G'!
@r6903
GTGTGCCTGCCCCCGGCTGGTACAGCCANAGGCATCCATCTTCGTAACATTACTACCGTAACTGGCAATGGCCTGCGTATCTTCNACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACC
+
;')2F2:E)C<H'+.+>@47FDH3)2*H:@*:+:=-+A-95)A**"BE*&<#1F!'9=@8=6'='1B!*5*-%)HE)HBHG6#(7"/!78)*AE2-=0<'6FB13(*)02*#'?B7@*'=2)@'*%2-E=0-CH&D
@r6904
ATCGNATAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAANTG
+
!(#)#&!+#'($#"(%"+))')$$''$#"#+*'#''(+'##*%*!"&(&+&*#%*&!!'!"(%)"
@r6905
GGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGNATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGGACGATATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACG
+
+*'#&()*(#'+)'('#%&#+%)(#++(!+)!&+$++(!+(%""")(!!)"#%"$(&*(%+!*)+*+#&&*$$#'*%'*%$*&**&&'$#&#!&&"+((%)$($$+""'("&##%%#%!*!"*#!"&%&)"()#%&#($)!$#'%'&#&!!&($+%)*%*#%"&'((#(++*!*(%($#()!$%&
@r6906
ATCCACGGTCTGCGTTTCCAGAAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCNCGGCTGGTANAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCCA
+
0932:CA6=&7G+F=E6>>*&>*:(0%+-/7+3B!(6<0$2-@G8-CB<B+F5#19F?!D9*(:.@1BBG%/&8!5.93F"#!"$"A'03,2=?<G??/&C/AH".!52#CG:2-5"+!1?068F"H,';0<H82-E4&"
@r6907
TTATTTGTATATTCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAG
+
*(&++)%&*%'"'"#%"#!++*""*#!+%')()+)!("$&$("(!"*+(+&!$))*''"*$$'#(+"'"!'*))%+!(#'''+"&!""!**+&)&+*&&&
@r6908
CCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACG
+
7E3=)C:D?'1#6.*5*35G/+"C"..'0<.>E$$320)%D0DB<'$D4,#
@r6909
TCTGCTTGATCTTCAAATGTTGTATTGNTTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTTATGTTTGAATGTGATA
+
$<+;'!/GF>!$&+65D1!42H()%()$C@16.!2$$78!+5*E"D$BF?;<C;--**+4A)$=>"G6F%?6>"@3C4B)2<>
@r6910
CAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGG
+
=:32+A?*&6A%&'H04#ECD@7)=.D-#.3@C4HB22+F(A.%%68@&D81?53F7C,H$%<62:
@r6911
ACGGCACATGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCNCAGAGAATCCGGATGAAGCCGGGCGTTACNGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCAC
+
D)017.--"26":8+(<"<BE6:B===B1:F4<:#9:3G/0B%;D%1)>7E=8&F#?E(E62D$'.16)G4!<%@%-="D!=G8$D:C5G!&/;@(G)9C7=94.&H&A:.>6>G-;:+=(>*-%1GD"((97<5C3'!?;F'=&;:D?*>B!F>+F$+).72HH"&-?15D2'8/:/"F/$0AAF,D>3?&D/0%
@r6912
TACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCT
+
>"F;>=&;#9A9F*6(:,D=F9BE(DBC!E+09F2'0"2H")6/B/,&7!@B3E<10F;>43,HG4<E<>D1>,?B(*#"ADE8A>A75@=%%+C;*+?+*0+A?D01C*G0;*$+E&<0=/1714#80+%?B7H7.7A)'@:)>%!!8(F:7#+G->BCD+;<=-"7D
@r6913
CTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAACCTAAA
+
F0G$<"&60'C2?:0/;6!2'9CD7<>#C'>EH;>D>:D/(=C;D*.,3-(490D"<<>9G7B,-2?6,.9<?,.-3B/61=6A6(5&+<!5H,2C.A*!D3?G@1D%(=DE@+"+C.''%%-+*=CDF::@#H
@r6914
GGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGNTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCC
+
,4'C&B%,366.CF(.C387C!A;/#<?8+H'68:6&$.*=H@,1740%G!#/GB"/#@/E(H//H)8E$B$7(9D<7$/?3:G';);D2@"+8,$6&A!0'"!$=?:7#4DDF.;9BG@<B&<8'7%/D9&6022:.%/*<+%#A+GH0";26#CGC%'@*!BA1!F:&43/8"(9B*1/,121+G'?9EE0;/D(/A=BC41F!,!#>(@'!H0G5*"EBE,G!4&=A50?1#(>F>#.;9"4!(66$&DG,F)FDA@5&$<9
@r6915
CATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTATGCAAGTCTGACTAACTTTTTTATACC
+
>-*E9B*EC<0<H;2(!C4"/D/A$0?:.H/-;1@,B4.9EC%"?"62;0H-#-'4%(:BF1/?>2A(G0%(.(4&G;#=)<'A"H
@r6916
TTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTNATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACA
+
7,-1+33;(4?21ECC/0+@.4?74-,3?>97"9;4,>-<<0C(:$EB#4>@G)18F74-$-<@,H.+2)&,?F$/$?3F;D&"HE&0,A)*&3<F132.D4E,/$>$-#<*=E$''0!24(F&G-(DG!6.1H:$48F,6%.!/DH$D:A;@/?<7"150>C3E1<H92;%).+7>#3?:/-B'.B0*+%?#8
@r6917
ACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGGCCGCAAAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCNAAATACAAAACCAATTTCAGCCAG
+
886?".C$':#F##@C*>1H(B@+D6=',A/&30$BBCE.B)+-,)28@$8>5%;>D?E4>)B4A'*#BF$/64)33@?183(!4*:%?<9#D:.*5+G@1@7@".AC$/8>3)!7F3='1;?(/A,(F20#@7-13&0.?-0.2>?(:7:E+(;;@31%G0/(>><GE)<6(;#:79#6*&!4(,<>AG/+<F=+:=+$09'2<;9-(06%7@=2%A>%
@r6918
TGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGC
+
8)H*B#!3H":/C;24(<-0+5A1?"59;5%4B'B13##6*B#*.=?+;?1!>'*.6=4-@*E=B@!-H@B*D.36?<#=8)=(AH=244536%484',%)4F$D!>='?;$)1C;0:E!);=4::C3@!D=#"H3*
@r6919
AACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTG
+
EG*/02<#C#$"<'G/4C896?6"2#H>;&73(<4D>4:)0=H-!5:4:#""/5+.,B&9&(0)9%@*
@r6920
NAGGCGNTCGNNNANGNNANNNGCANNNTCTNNNNNNNCANAAANGNATTNGGANA
+
#!"$$$!!#"!#"#!!"!$!!!#$!"!##"""#"!!#$$!"$$"!!!$"!!$!$$$
@r6921
ATTGATACTNATTTATAAACTCCTTGCAATGTATGTCGTTTNAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGG
+
*6-&6/+@63B2.3*4BE/8=:,9#"!$,>FF8A*9C&:#E+(9-9E)>;B9'C@3<*5*C>7D286B87.'G'>?>F?DG95)/%@*.GG9.>:94'4@@!4?%@5H@/,,&';#2%26";-D@1.E#>(=/04#)B3
@r6922
AAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCC
+
*7#8F&#&B4+&"4"""-1='(?/>'3A3!@AE"/?(BB)(2(A,+"$2GB%-/(FA%?
@r6923
NAAGCATCAGCGGNTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCNGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTC
+
'@)C@'/+1?:/H(.?=4+6?!.B!E"F42."3<47)G&1G8H*C(=/(91)/#96F8E?H'0+$D-<1C7*>A-1?<0>F;!#E/:,-+@9;78;7!1FA)GC8B#>2B%$G$1H@5GH6)HG*F"6#%:55$)827(#/$4E1/-7G);/$HD&,$25?=A>A&-:9-G4D&9.%,B46:(9B+,?AC'6=1=">E7,EHH%0!59"8,$%)#1"#$
@r6924
GNACNNTCNNACGNNNNTTNTNTNNNNNNNCNTNCTNNNCCNCNNNCNTGNCNNTNTTNANNCNGTCTNNNNNCNTCTGNNACNNTANNNGGNCNCTNNTCACCGAANGNGTNTTCNNCNNNTTNNNGGNGNNNNCA
+
!!##!#!$"#!!$"$##"#$!#!!"!!!###!"!#"!$#$$#$"#""$#"!#!!""!!!"!!#"#$####!$!$!"!#"$##"#"#$"$!#!"$##$!!!$$$"$""!$!!#""!"!!$$$#$#""$#!"!$!"#$!
@r6925
CGGTATCGCGAAAATGTATTCAGNAAATGATTATCAANCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAA
+
9@033:3E,5@.*56F<HD6'<6;.98';;5G&9"7:,4!$=C>'*6@$*$6A5G(57F><-+>@H*G70-!:+?782H0<F84.?%78G*2=,1=2$B;!A=)1)B*@23'6DACC#<9?"0@?7<7F?@<=F51A%=;#/"/(3(@.$$@E@E#F<(!C9#H1!1E!"FC/%9G"E<A12D
@r6926
GTGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATNTCATTACCTAAGAAA
+
%#)+'#*#)+%"'%)%"'$%*#++"++**$!$*!*!""%*(##"++%"*$)$!'
@r6927
CATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTC
+
4H28&-,A2(F?-.4/(0"%A<445E>&CE=>%/=;,>8'<G>03-2/=:#H1-60EA7%"D"6E#+$2D.;1"F0!"ED>)18C
@r6928
CGNATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCNGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTANGCTCTATAAAGTAGGCANAAACACCCAGCAGCATTTTGGAATAA
+
:,%EGG>44$?+3EA.A1FA:!70<8#*,94?8#)DC'6%!/H730C.*.E@@!-"</:3!2D-A!9=9)?D>/<A5>#DB8=4B1*/#;F*131)?<(-$:BFD14F45D#,!%5&CA46;?07%$7:
@r6929
ACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGNCTGACAGTTCAGAAAGCGTGACGGTCACACC
+
>%#(D-"9%+%7D3FA;6,)?4'"'9A77*/!A39/CB>,C;,F(+E2&#C%93).@1-6GAH'36F(#&2&$1G2;=$>$#>1F:"(G60E(8B<#6$@)3$:)+$6'*43#:8,1-0B"/*2($3'.&#$3#<47A:.4%6D9"
@r6930
TCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCT
+
GD"17G,=>:;(G5<FB*&3,<@7#<7)85&'4(8&%!7?G?AD<-#;E=/3G:C>(B@H770AC).C2%?A967:;%:!78;.FADBH;5&1'C*"#!56##$.,'244@>9HBEH%'G
@r6931
CTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTGGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTC
+
")"+%'&++!$!(++&*#**'"&*$*#)(*!*(%#&!&(+'#)))'"*&+($(*!**!%$")*$)#+"&+&"'&&*'&$%)#'''*
@r6932
CCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCAC
+
2(B/H.?E&%D.%7B:?"0=27'4==04@1:4?:!3CDE**2D/9&CA;4&><&CG&#:)2&H%9:E<1G#@<0+)9@1>&<#<@0?:3G6%)C&>FH2
@r6933
TCANATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCA
+
#'*#++"#)(#!#'')*$*&%&)#'!"&&"%'"&+$+!%$)!%&&)"
@r6934
CTTTNCAAGCTCCGGGTTGAAATCNACCTGCAATACGGNGAGCGGTATATCCCAGAA
+
))%$$+&+%'"+"&$+$#)$'()&$&#$+')$!+#$+*+($!))'!)*)#&#+#)!'
@r6935
CTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTGATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCANCACAGCAATAAAAATGCGCCGTCTGAACCACCAGGCTATATCTG
+
(%7G7F?-1G%@H8=>2E)*G3")A!C6;(/%1*</?$@&A"G-;6(()5?D132!8%B7GE2B5>C?:?B8EE$>F,C=!A9'A'-1(:0D,EF:#%8"#9,#8C&#H$A721-E%;C?$3:$&+#'0#B*1$D2
@r6936
CNCTCNNCNNNCNNTGACGTCCTAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTGCCTC
+
'%)''$$*#!!#$"($&*'($!&&)+*"+"$%*""#++&$((*(!(+$**))&"!%*&%(*)(##+
@r6937
CGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCNGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATN
+
8!G+8)5"+,6!%G1%7C#(%6%G?7)*D#@DEDGF)1,!75"55/):0868"!'$GC>:+/?H1"@=3/H/227F$DD%5A:@?6/D2:,1@D6$BA5'+"6:;3#.G&0;:!G*&+//*&2=*!)C0'>@E&.;':74"&:&
@r6938
CAGAGAAGCNATTGTGGGTNCCCNANTAATGANTANTTGCCGCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGANAGG
+
')$%)&&'*"(*'#)*('('*$)$"$)$$)*%$$$%"#("!$+)''+%(*$*#*$#*#"$*&'&+%"(%&%'&*)!&%$!$#&!'%#'#+")!(!(+&"$*(!%)''(((**&"#)&"(($**)*"###"*!((&%&!(+&%("&"%
@r6939
NATTGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTT
+
!=;5<+,!%A9)36#H5E93GG,8&'FG$7C@<DG%*$?=4!.$,=&'6(:*34$.B=-:7162>4(*?9@A
@r6940
TGATGAANAATGAACATCCCGCGTTCTTCCCTCCGAANAGGACGATA
+
52%B<@.39/#88*#+"78&FD6"2:379-%@))8G()7/*@67A4,
@r6941
GGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTAATAACCGCTTCACACTGAC
+
E0<A';;5:C-=92>B1G!E03;&;F8':";#EC2.5,;G*DC-0F$8+>A7@8$<9E@FAB!(2:&4
@r6942
TNGAAGGATTTGCTGTCCTGCGTGAATAGCGTTTTGCTGATGTGC
+
)$*+3E9D,?%<')A*1:*H%4DA=,#9E#,F:8&*811%9(,B(
@r6943
GATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCTTTTACA
+
%,F8:'$1;01@40(@/3?4>;=(A8+>E8;(@&3&513C3+:$(207,505?6&*B1<44@3?-)-
@r6944
TGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGAT
+
H?91.!E)8%D>%.0(,D9&*$%D(B0*1@7:B#C.)>-";E9F*9H4?&2
@r6945
CAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTTCCTTTTCCCGCGAGGTTGAAGCNGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCAACTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGCTGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGG
+
%=4<H/A?3H#8D6C#3C@$);*#.>@'B,2-8/%H10#:'G>'=<-:%B%+,HF"B;?.980>CA/+;0291A)-4;"6E,!;1%7:34F,(:-*7+52A*,0/8H-?:7;D7F>"D'7A,EB$0(447'*.,6>7A#14:,B8+9$1%%66!G??+$.0<,F8$4B889;78'H6"3#!-1%11F)2)5")@%)&>9H=B?6B$>'<*!2BC,#3)6%?D'GF$#:/5%-="'EC:G/-81.1$?H:!A-1/?F:E*,>G=H4A9;*0$+C:&+5?:8:-;18D6%*H"H57A+&)<;76=:'!9%A6*/+0H/0%63293>F3(%B@*3%(@=A6%;#CC<?26G!7<@-(*
@r6946
NGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGA
+
"35@4H$,6A?+5A=>%5&.G.*9+9G?*9#8&61&>BHF-,<6@
@r6947
NAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTTTCCGTNGAAATCAAACGCGCACTACTGGCTGGTNACCAACCTGTATCAGAACATGCGG
+
&7!1,#%2H2?HC+1%"($H383@08+"E;A9?7D,&:=&@)4B+-7<*0CDC.090?8$#A)&A2>%H5,<()2&H;;''34&'8CGF6-7F>/H?&E>2C!=AA1)(B$<":85":B")07/5*78;(?''A%#76*EG7('#2!*+(.$7)6E09@
@r6948
GCTGACCGGCTGGATTGGTGAANTTGCCGCGTATNACCCGCAGCGCCGGTCCGGCTGGGAGGCGCANAAGTACCGCACCTGATGCCGGGTGACTCACTGAACNTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGNCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGC
+
*?D:C-928!"E;:8/8:/)&;HH1D9/E4#<%8!-3$-%@!>0%?+>E7()9F(0D<(C21"BH$7$FD>=.4/:2@0.%D2',(6?F2-;"%C.9!%FE%"212?02@D-!<E2!0*D<):&/-0";'9$&6H6'*4;$H105'C>,.)F58D-(1HG%>01/7B@9-*1C>:D!@((1H1F;D"43H;&.1*8H/=1?H'&-?CE59H6,9,$/7'E':@/A
@r6949
GTGGCCCTATTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCNTTGCGGC
+
@;AD&@C#G544)#@D##*D/;2E:4</B5'E>@$+(.&)*)4+%'F5:?%7&B0>,'BF9*!DF0HA!3563=%+/!E1+0E,:0138%&))9,4A3B:%E8@*B0F'5FF65(%"!?)74%A1'.0G3
@r6950
AGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGT
+
C1H1D57&.0G!C;%F5$GA0/5#10,B-/F'&</7"27688$
@r6951
AATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTAC
+
B-0EDA1)/G3%%!2B)B58464@;%*A)9,+5F=E/9!DG,DEA>847!%@%2?5;6E7=1H(8E4&0'8FD&,@H'0523-H3&7$-/)9)96?A6:+*;%0E%4H6,G;F1<H/29=
@r6952
GATTCGAAAACTCGCCTNAAAGCCCCGCAGTGACTGGATTAAACAAGCCCAACAAGCCG
+
+(D,9FH8#4EH2,;@0$?*)9A<9:07A14*+&104''64A=.BAA%HH(?%53A@.0
@r6953
NTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCANACACTGCAGAACGTCAGCCNGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTNTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGANCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCANCGTACCGNGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGNCTCGGCGTCATCACCGCTTCAGANGTTCACAACGTNATAGCNAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCATANCCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGNCGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTC
+
&+"#*"%%)$(&()!!'')'#&'!))++%+"'&$(!((++&"(!%+$"+!'%&#$!(#*!)#!$'*'"%#"*&($**(&)'&*&'*!)$*%''*%)&&!%(%!+#""*+*!)$"$$"#$'+'##&&$*('")'%!)(*""*&))"!(%!$%&"(!+&$#)&+)*""''#''%*#"!%%!"%*'"%$"!+*"'('$$$)#&)&+!!!#*$)#+"***&(*""("""!'$*#!'(#(+(("$+%#$+#*!#+"(#)#&"%&('&'!!")*&'$%"*"(!(()*!(#+)&!'$!'%&$'#*#*&%+"&"$**+%"+((%%!)%+)&)!&#'#&#'!%!('*#+*($)")#(##!'(&'(&+%%&&%"+%&**!%#*'&'(+$$#+))!*+")!#)#%#""*%&(+&**$'%&+"+%)&+((#&'*)%$'+$*(&+*!(*+**"++(+)("($'%)!)$+!+%'!'!"(!$"#*'%*%$+*'!$%&&#"($%%+$'#(&&&%$&!+&$%"+)"&*($"$$'!'%!&(&(%&*#))"%%&##&&&$*'*!)"+!()#%$+&"'%&!"$"&'&%%%()('*"*#&""(($'#&)#%(()&%'))'*)%*#*'"&')(()$*%%"+#)!!#"*!!"+$$!"**!!"$%#%%)"$''#+'(!)("$"**!(*)#'$$!+(((#('#$&#!+($#'!&"%*!*'%")(")##+(*%%%
@r6954
TGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGG
+
2F#01<C!(4$%1:-C:A*'-+"<6.%B).*8'E$#AB&)2.<@5>'(F-56"*)9:6&D?=+0&&)A6,%C-+&F8E/"?3/(16(G$6$4EF
@r6955
TTTCCACCGTACTCGTGATAATAATTTTGCNCGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTT
+
HD"6D.B<$>+'G/G1C%!'B(*-:#',F(<-E8/*>)D9<>,1"6H7)47&G5*E;+&590$F&&+:.&>
@r6956
ATTTTTTCTGTCATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCATGGGCGACAGTATCAGCCGTATCACAT
+
)42;/B6?7/!&1.2;7.%>,5%E=)E?>4DH,<77-7G8#."=*$"&/.!!DE24315EB11??2"9(-F@8@.H
@r6957
GCGAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGG
+
#)&HA*)3*A3*>FC/&-'2/C4#,FGA&-&G;/AE1#$%D7/.1/7#(5*0)-)..=/,D,(0@'H5:#$:5)2.:B79#=6H:=.>"4*"HHGFD!3-+
@r6958
TACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAG
+
4+H5H7!(&,C6C&+6),@::)G*1%169>$10@3)@>B86FF7&($,'*
@r6959
GGCCTTTTCACAATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGACGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAANGNCCGCGCAGTCCTGTCAGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCTGGCGGCGGGTCTGGTCATCAAACGCTTTCGTTGCGGGNTCGTTCGNCGCCTGCAATGCCCCGGCTTCATCGCCGGAANGCTNCAACTGAGCCACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCNTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGACGGACGCAATCTGAGCCTCACCGCTTTCCCCCNCCTTAACCAGTGCGCTGAGTGACTCGGTGGTCTNGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATAC
+
+*+$')%!'%!#&!#"&+"*$('!%$!(*)#%%%'+#($(($(+!'"$$"%*)+*%)"$'()#('('#$)!#&#''+"+&(&$*'')))!)%$(#)%''#*%(*""*'$&+"(%)&"%*&$+'%%!)*+%&++!+!%!!"+#"#*))%&#*($+(#%(+#)&#%+$+*"!&!)!(()(*+$)"(!$'$$$*$(#((%%&)!&#"%"$+(&+'%#&*&$"&&"(%+""!'))')*"'!#'($%"%&%()%!(*"'$%+*'%&#'(($&!&'#'$!%"'''!$%)+"!%#%)+$#!)"('%##'('(&%&&$!#)!$&)!'$$)$)!$)++$&)&$'&&*!)#+!#$(#)**%%!!!#*%(#%)"#)($!!#'&&#(%(%*$$+)(&($"!"%*#(%&('!)!&$%$$'&!!%(%#*$%+)%$%$$!!")'&)*'*&#!*($(#&%&*!%($""'!!$"(%*&'#&(+*$+()#+'"##))"+%"""!)&(((%#%)!&)#)+($##!##*++$&#%*#*#&'*%%*)#!#$%+$+&"!*$)!(#(%"+$%$)+%*%#$+&$#&&%!$)'"'&(#&()$"!!$!'"$'*$
@r6960
GCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCNCGCCGAA
+
H&,4(:C/&0:*05?,3?942('6F<#-&>0!7+C?=AB!(?C>!#5'/0H8,>90FBA1+3#8B(?>)7"2A2-B,/:B%#E1-#..$&+@=A
@r6961
CCTGACTTTTCGGAGAGAAGTCTTTCAGGCCANGCTGCTTGCG
+
??-DF20?7$$#>#<B76;.=/9:-D@"76)(C/H'F;".C@#
@r6962
GCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATCGACTATAT
+
1%.FB7G+$)HG0:F,>!5!?*$$A>9A*BD2D.#EC3,1@2(0A)/>@07,
@r6963
ATNTNGCNTTCTGGCCAGGCCGCGCNCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTACCGGGCAACGAGTT
+
"*#*'!%"++"&%&#"+*(&)'&!"!*##$(!'!!%*"*'%(+#(&*'%&#++''!+%&)"("")#%(&!&&($$("#!+*+%&'&)**"%&$$#$!#!)!"&%+**)(
@r6964
GACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCT
+
899%H7'C/(!5F$:)B.!A*.7%9E=(;45'A$>21&5;H'H!#2A&/B71F''2#7&
@r6965
CCCACTGAGCAGACTTGAGCGTTCCGCACGAGATACATTGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCT
+
3->>A(75H9&0$A2/:0A+600A*AD@3+(50(HG.49)4*@362&)3*6@FA:63G*E,5)H.8>)$4D!;83C/!&6EFG49)FA:
@r6966
CTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTA
+
>8H)73A#58F"&GA(A'#1D>G<F,EC/7)6CA0EH6>99G1C/B$A90H00:)6<1"@(0<*G%1$8'-)?*
@r6967
AAACAAGGTGATTGANCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCNTGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGNTCC
+
5>,"G0(G%*$+D7#;0=1-5,*HA.?C0G7+;6(+F0;,A%GD&=C>.%1.,=;0=?/.6%"G'"9CG0C8(A<;G28$=%D;F6B%D1!//>0./A!4G3!-@7=A3D#/(B>=?)8-7=&.;%*1?D+#,E<%C6@/4
@r6968
NNCACGCNCAGGTNCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGC
+
"%$"'*'#&*"($&'+*+"!")"%%)!&'")#$#(#"%#!%$!("!!))(+)
@r6969
CNGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTAC
+
#!4-820F=FG>#"%/<(;0().%C83E'#08=9B%:!-'E,90A#@BF7.(D20G*+&.>0/'7,0A1%G"4@@<3F-.8>'8<D+-(-GA;C.--:
@r6970
CTTATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTNTGCGACGTACTTGACACTNCAGGANTGGAACGCACGCCAGCNACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGNAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGCCATNAGCGCCGGGATTTACCCNCTAACCTTTATATTAGAAA
+
""!+"'*+(%$$+!"!$&%+(!*'&"*+'!&()&(&%%##+*"&&#")+%#"$()#()+"#%!#+!")*((++'%""+*''!('('*)"')$!$+#'#)%+*#%!++')$(+(&'"'&)!(*!((#%"+&"**%)+$'(!("'%+)!""%%$!&'$%#%%**$+$&!!**+#%+*(!(*%)**+!%)'"#)%"!#%)**&&(++&+&$!!)#"!('&)%')'$')'+$&&)!*)!+"$#)""%$+#)$+'"+*"*(&""%"+'#+)&+!"('**(()+*'#'!!"&&$!*!$'))+#(
@r6971
TAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTNAGCAGTTAATTTTATC
+
<'$,9/;/!/')%(;6D8@@3%D#D1FB8>A=+8.)GFHA?58&D??H+3E-$@=2(=*9''<
@r6972
NNNACACGNNNGGGATTGCGGNCGTNNNCNCTNNCAANCGCTTATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGGAAAANTCAGCTCACCGTCGAACACTTTCCNGCAGAAACAGGCTGTCTGCGGGCCCGGCTTC
+
!!"#%)&%!""")"'#"'!$'$*&#%''""&%%%$*%'#)+"#((+((((!'#))#+$!&%$$$'""#)("%+%$#%"+('+$**'&&!#!'(%$%"(#'"(*'($))"%&+#*&+*'!(%+!)+%&%#$*)*''(!!)"'*#"+%%!&'%++&#!%%+$+%+$%+%((#)&%(*%#)!&#()&'&)'"(!%$$*%+&)!*"%!')%((+(&'#"*)&'(+(+$*++&)+')+
@r6973
CNCCCGGCGCAGCTTTTCGTTCTCNATTTCAGCATCCCTTTCGGCANACCATTTTATGACGGCGGCAGANTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCNCTGTNCCTGCCAGTTCTGAATGG
+
&"&!+#*#&)!"%#$$$'%))+#"(++%(+'"+*+("')*"'(*&$#&#!(*(*%'#"+"*)!!$)&&)$)$$('(!"$$&+'%*+!+'&%(*)!*&+)%%+!)%(!'%!*+"!"$(#++*#)#(&(()!!%$)#!&&!#**'
@r6974
AAACAACTTGTATTACATTGACAGTTAANCAGTTAATTTTATCACCTCTAAAATATATCAGCATCT
+
9.>!EA=%0#?)<HC<E5%/8-/=$B?D5%@9HB!>)@5<9!!C?6&D=!)'60H.?B9*A;16H6
@r6975
GTGACGTTGGGGGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCC
+
B941.C>6:A/H>H@>7/F*-+F&3,;F1:0;'+77FC=4C:,&9(01$"D)5=1'490A%?#*(:H2=**E!8@9G2C7E&E1@95'?.HC:B!6?<.(E$+6"9B$/:))"G9?
@r6976
CGGTNAGTNGNGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAG
+
#$"$!%()!($+$%"!"$%**)!)'"&"%+!#$*+)&*(!$+)**("$'+%$!+!)$'"()""")%+%(*"##!%)%*"
@r6977
TCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGAT
+
D,-%A.?AA0#"96=$)2,2"GB'!4%&&A+G6B"'2/#5A@%:"+%H==-(,"/&-G+1&>
@r6978
GNNTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAG
+
)!#()+'$$$&$*')%&"%(*+)&*)'&"'##$"#%)((&)")'!+'#+&""(!%&*"$'&'$*'**&%!*!"!$##
@r6979
CTTCNATATGNNCCCNANNAANAAGCNCACCGGTTCCGGCGGGCTGTCATAAGACTGTTTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCANTATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGCGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTNTCATATACCCGGGAGTGATTT
+
"*"*$)%#*!'&&%%$'&!%'!)+(%)%!'#&'+'$+")(&(&(*!$)&!'(#++#"+)(&(!&%+$("'$")"#$'##&)))%%$!#')(!''$$++"'%+&$%))"*+++*&)+*'+%#"%"")''*!"#''#!"'*!(#$"+&!*$%('%#"&#&*'%#*%"$$%)#*(**%*+#+#+$&$#)*"'"'($*&!$($'""'(""#(%!!$*!++(!+($*%(&)*!&##"&())%%'&&)'+&%*&)$"++!(#(!+$$"*+(#%!
@r6980
NNCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGA
+
)&+&(')(&##"#$)!#)!''"+*%+!!++*"'+$*(('"&&%&!+(&#'""")!&)'$(')+$!!(&*)%%'
@r6981
GTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATT
+
+=@43";-1#7%;03'B;.985'5?+749-7--$A#F*"H@DF%,B1B$59@9,D.(0.8GF#8EFB%A6@2HB>?:/C1?.DB39G/559HC3FD)F>6240A-1-D
@r6982
TAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACAATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATT
+
3'&*.E8?98B);:?3$<;-F;;@E,E>C?F2G<BG#/B,,%-:)2/"HF+917/(H6$;*>H6;B6;,-);H2*10*76A.7&
@r6983
TGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCNGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTC
+
*B&$B<FG6/+9"@F4%E*0,F$0D;$CE?7"431E8=+D'!3:#G;4-83$4F:D4%D#-9G"=9;8="19-1%0,D28@E++A5%;HAF?-694C.5E2;#52#,-
@r6984
AGCAACGGGCAAAACGGGCCGCGATTGATGCGAAAAGCCGGGGGCTGACTGACCGG
+
0A&84&@2?$BC?+H<(+8H$(-%98+$E1;997H58"2+=;EE0;9.@BF%HB>:
@r6985
AAGNAANNCNAACNCAGAGCTCTTCATCATTTCAAGCTATNAAATATTGCTAACANGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGNATTTATTGAGGCGAATCTGAAACCTATTATAGANTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATNAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATACANAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATGTGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATG
+
%)&#"*$"'$)"'#+)*)"%*("!!**'"%!&%((*((%&+(($!$*#+*+#*&#)!*$)*"!'(%&%#'$+%!!"&'%)+)'$+(!%+*#+'&+("%%&)("((*$"!&&#*)%&$$&%()%"!$#'(+!$)&"'$&&"$&%"'*'"&)$%&"$&$(&$+'*$++$'(#&&%#!)'("!"&*'#'*)+*)"'"#*$("')(*)%*&(!*$&*()+)$(%+*)++*&'$%&)!'(#)#&('&!)(!)!(+#++"'*&&"!+!*()))**&$)%#'%#&''$%&()'+"!($+*%*%%($%'+"'#!)*"%"()(($!%"()%)%"&)#'%&%$'$+$"*$#*'!%*")*+*!&*&#!'%++$)"#%)%*'%*'%!%''&)!""(*)"!!!&!"*&"#(&#(')#"%*(+*#()&+&++$$+$'++&##!*%'&''(%%%##(+!'
@r6986
CNAGNANGNANNCTTCANGTNNNNGCANNNNNNTGCTNAANNCCNTNNNNGNNNTNANGNNGTNCNGANGNCGANCNGNNNANTNTANCNNGCNNNNNCNCCCT
+
!"!"!#$#!!!"$$#"!!!!$"#!$!$!$$!#!#$#""""!$""!"!!"$!"!"##$$!!##$##!#"!#$$$###!"$$"#!$!"$#$#"!$#!"$!"""#$$
@r6987
CCGAGGTGCTGNCAGGCGTCACGGTCATGCCGGTTGCCGC
+
8->6<1!8G7""3)/$)<;/=/:+6AG/G.+'9G6:C3C#
@r6988
CNCCCTNCATCAGGACGTAGNCAGACGGAACGATATCTGATGGCCACGNGATCGGCGC
+
&"#&)&%+"&#%&!*#!"(+&'''&#!)*('($+$#*"!*+&#(!&#%'(!+%%#&"#
@r6989
NATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGNACGCTCGGTTGCCGCCGGGCGTTTTTTNTTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAA
+
)$<?H#1%$.+;<D;*B4D,.:5C6;5G7":A=H"8G82F<:C4(F>*6#2,#A/AE,*@9"9"**3DA@@70#%GE:8C,522D34=6>*C0+;H=C<AC;/>$@+/?.0$->56@";!*3(?%@2#.;8%'-;=#"":9
@r6990
AAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCG
+
&?A:'7142#CB:@2&4"3H9EAB#C/>>@.3'1<+-'/&"*$;#DF)(7%)?G+F<<C5:)/20B3
@r6991
NNGNGATNTNGCNGNTGAANTAACGCCNTTGGCCCCCAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACNNCTGAGGTTTTCAACGGCCTGCTCAAGACCTTT
+
#!#(&)"$$"(*"(")#'(!)*)'*))!+!))$&$$($)'%*!&(&$&&&+'%+&#%&$#&"%*!$&%!$$+'))($)$&)&*#$%&*+%!)()'&&&#'!#&%"**'#!)&%##
@r6992
CAGGAGTGGAACGCCCGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGG
+
3&@A!*1A=C3)/1DE3E>"5&*??+&'76(;*="=H01B0EAF9!1>D"H7H<@.64
@r6993
NTTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACA
+
!CA9,'?-CF5:F0+"45CEEBF</C*F4314-8"7!/626-3B9&<17-'*/-D.$G"C"#<'3/)C12<F76@-%;!,*3$5=-#B?+$H=.C232AEB>'6%()*(<D/%6E2)*2&??@%0CF!<%4/AA')D=!G?&>;:+3!GF)""9C0;8DF2C3F)@C#;-!G)23-
@r6994
NTTTGTTTAAACGCCGTGGTGAGCGGCACCGCCATCGGGATTTTCACCACATC
+
%*(&++)("+)*$!$'$$"%%!)&%&%("%'+$)!$((!)$%))!*!%!*"'!
@r6995
CAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCNGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGNCGACACGTTATGGAACTG
+
58+!BAFB5<9@,$$!512+A83.B45517<9>3-;?8?'*@:F<8,B"9H<!*?680.#>&98=/F.!-$;2>%"=-&B:)(!H%/=2=':E((F/+>EA(1+E)48GBB="56A*1(2=8%=4*6'=091
@r6996
NAATNATGTNTCNTCAAACCTNTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGNAAAGCTTTGTG
+
)")%'$#"&!(&%+"'+)(+&""$!)'&#'('"+))'*'"###%((&#'&%"$#()"%"!'%*(%$"#!"+)
@r6997
ATTCCCCGCTGTCTGCAGAGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGATAGCGAGG
+
=.73#+A-/,!6:0-A2B$5D2H<""280357&AG19>-01-%A#DCH9#3+::)F>5#!'H@9&(-0)4$)+B/F2%D0!1-2@+HB#"!CGC.4E62/F6-*!,27):?E8:/82FH/20B0H.GF7F?5,E&1D,E:BG;%01C:8&.-4))>,5,%)
@r6998
TGAGTGCCGAACTGTNNTGTGGGCTTTTCTGTTCGTTTCATCCAGTACCACCTTAACNGC
+
*!'*$*(%%!*&(*#$#+(!&!'+(&'+#$&&"#$$+!*""(+*)!'%*)&#$#*!(*'#
@r6999
AGNNAGTGGNATAAATCTTTAAGTCCTNTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGACAGGTTGCA
+
&($#))&*"!$(+#!(!$##"($+*"'!")+&+!#*)"&*&+!%++$#')"$%)%$%+&""%'$+))++(%'!"%(
@r7000
AACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATG
+
B/@'E*67'GD+F8B6>,$,!95='*@);"!74?5A&)?E4%;3@()B@+>G"55:EG
@r7001
GAACGGCNACGGNNCTCTNTNNATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCNCAGAAATTTCGGATAACAGA
+
")*"&((#(*&)")'!%"$'$!(*#()+%$!%'+"'&('*'%&"$&*#$%$()%("$*(!+*&""*#*+$'+$$!(&#*&'&'*&+%&'&&+&)!*#*'%(("#)$!&')%&"*#*()*'$%"")&&+$""%#&&($#%)&"&)#%**'')%%!*()&))(*"
@r7002
CGNCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTAT
+
0C9:,>.;BGF>605)5>%0#%4@2+/7A''3:;%3)"-&7*:2F.?
@r7003
ATGCCACTGTTGCCAATGACCTGCCAAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTC
+
B#E;0D2)-%51%!C3:;".!9&F<35:F*#=B;-=2!#(8+6A;2C87!@#7A),6>(GG4C9#-!.G&:.%?.E85)2*0>*=4@4DG"@0G)G;/=+
@r7004
GGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAG
+
F5,4BE576&&1</5@+B=<<@7+$:6+;'A2=HC=E:C%>04F02&:./6"1?!C08*G&F"<9&$#!F)94&$+2"43#>?53@<A?D
@r7005
ACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTG
+
8$2;7%!F>D63@HC30.@$##@'66$!$2:C(<,2''G);C-%BG!F(."D/-2.7
@r7006
CTGAGGTGTCATTGAACGAGTCCCATGTCGGCGAGCATAAGCNCACAGAAAATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATNCCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAACTTCTTCGTCTGTTTCTA
+
&5':(*!3-?B"=F+5/G$1A1!>8+$($GB:?-99*E#$2-.E78'/97=!5%<+7F#!;H>41?:;<)?H96&#61;=-7:4,$:B'BD.@/7FA+92;)4H&A6$"*'B'G&/86:2+2G5'>AG)$0F9(74/5D#B*?845;)+E.'0E#2+'B38=;9-=&D/!E:C(1F/H:824,;(%<E!
@r7007
TGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGAC
+
(//E)G'7F-":,'5A36E8@H"H9-5C<!8G)*'DC7,A+%/E7.(2C2;/C&//>.#/;@F6;F17@:)/B$4&%?4*'>D=68@G75A.6-H(5?C->.:+%&?90F8=4(?%4#,H-B4C;;)D"F;#&G'(>)&$2-($@E7H(,51A.3;H9:).B"2;-7)%4>>9&2'C)A)3::)!@-!0",'#,8?#@"1@A5+1,--*7*A!>-;>&&A%/#)5;28-56'H$0$F2B>7CD%@8).C>,335D
@r7008
TTTTNCTGCTGAGGTGTCATTGNACAAGTCCCATGTCGGCAAGCATAAGC
+
:6EEG-A&3/@";E6$D*>#1,G8;9!#)0>=G)/*+/(7*F@-4G@/90
@r7009
ATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTA
+
BG1H4+>F07!,.02"/+.+F&;%H7-DDE6!C1G"CF=14"
@r7010
ATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGC
+
>0(:$.5$34C)(>H8CG0C)B&9"AEB%=+B9@10D,!C"-<<;@(A/"D%13
@r7011
CCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGNTCGATTTAAGTCAACCTTT
+
4))<?.,'E;.E7B"*0C93&C/-.@>:H,!4&D,,8G(C7(?,G>,F4&!C7)+6DE;*#:"->.-*)H3D4(DD<*>75*H-
@r7012
NCANCNCNCTGNNCNACNCCTCTNANNTCGATCCCGGTACGCTGCAGGATAATGTCAGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGG
+
)"'"*!$('&'#"*#'(#$%)$$!("#"$)%(+!'"!+)+'+&"''%'%")!((*#*!)(+"*%$(#%*'*'"*!'*"+'')#''%&*+*+$+)"!&(''+"&++'&%($&%&"!)'**%(!'!"&
@r7013
TCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGNAGNGATATACCGCAGCAGTGAC
+
:)60H-@5/".>;')F6HC0D8H,<943;E5H>177'<-!(!#)-6)C!39,2#)##.!/F,&/#16<+53
@r7014
AGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCAT
+
6=<EA8<%&#5#/9#7BE?/112*>!!',06+C:DC,%/#//BH<6?>;4:<7=8A)C@&9@+H5/.#-E?#?,38/F+
@r7015
GTCTGAATATCCTTTGGTNCACATACCGTATAACCATTCGGCTGTCTAAGCTCCGGGTTGATATCA
+
0-9A"?*9#<1)B,)1A48(<C?8?:.;5*)(DGAG'=.5(AG=,#2G7"C;5FGB3?*E+4!=,"
@r7016
TTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCA
+
5<-5(38A=909A6:#*<&?00=3HG;$.=5!A-DE,?*,<8;E27<&#
@r7017
CGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATNAACAGAGGAGGAGA
+
AG@:+=841,%"?*!=#&,1*)+8"4G:7@7.:C";(!G<1=2/?9(HH,7*&&!F;F4.6!;?HD51G;E5"<F>A8+7&A
@r7018
AGCTGGCCCCCACCATCGGCAGGGTGATCGCACAGGCAAGCCCCCTGAACATGGGGATCATCCCTCCGAAGGAGTCCTTCACC
+
)(""&&#+$*'+!%*(&(*("$((*"+##!$&+#!%*$"#+$%'$%%+)$)$*$+$'*%(##+*$%*"#&*"*&)+&&"$)#*
@r7019
GCTGCTGCATTGACGTTGAGCGAAAACGCNCGTTTACCANGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCNAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAG
+
?D8,H?<0,(.HG;6<91*"#F(99#A>;82B:D8(H>=&E,/:CFG*&E$3A4!9D2?+6#>"6&%=0!'#',@)G6:F<F>7,<D!*"-8/'BC4+-G+-5G<;'5)"D-9H3""4-623G!.E/'1+DG0+A7@(%B..F;+:=2/B86@##&EB-*8;5?"@1?(6H,0+6;#36#4A%0C@2)E$)%"A#C=#G+.)&:E*=-)C0*:E=
@r7020
TTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGNAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATC
+
=?2@53FD0D?9?4/A6>GH"9%'$+@C#D-'BB+<$6;'2B.'B'2/)E6%!4HC%4)5%#+B,(15?*,8=#C&>A6'01$3=@79FA242?049E9?;+4A!+F*)$788D(3%!+"?<)>5/='F-<"CA+5??5*,(4=8"!!1/=67G@@=?28:'G"(:$'A)E5,A@EB
@r7021
CTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTA
+
6"@9?F(EH-$2*6'/0+@(/#@4'1%8$87H.@A50-HF<E#:
@r7022
CGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGNGATGCGCGG
+
',355*&2/0-"'-H4'1#G"A??FG4.D6G<:,99$-;%18>1AB8&(%5=G*A53F'$&@%$@9.C2A*<=4?&<<GC
@r7023
TCGTAAGCAGTTGCTATCTCCTTTTCCNCCACTACATTCCTGGTGTTTCTT
+
@4&-B!B0-87#FH6&2":D3.>:"("HD,C=F?E,85+864,;,F(9;F9
@r7024
TAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCANACATTATGTNGCGGGTATTGGCCTCAGCATNGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCC
+
/=2F94/@:5F;9F;,FG1GG#&0>#9CEH@5D$<017%-3<H92("32<#<33!<5FF*D<H)""828%9*>91HEA($@<G><5:;,<(53@B.>4416+CBC%*B045>A
@r7025
GTTATAGCGGTCCGGCTGTCGCGNATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAAC
+
88$!2FG3A)5HH;01:=56!.1E+12),-BF31/"9$4$C6+*-;9;EC9@G?0=;%?/1;+H3:')H!B!765+*7/CA7$$*<D+==+!@=-9@D@12='0%=*F:%>1B
@r7026
CGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCTCCATCAGTTCAAGACGACGCAGCACCT
+
GE+5B'-&H<CA=.4@1=A648A-C$:=!@G'#2A?14E<05@>F.8<)FF0+!&23867344"HAB,G)+:=9HG7G.)+1?-%53B,>>9/G"1$+%7"475,B*F263%6H$>)'3,E:C;+
@r7027
TGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCT
+
3(1*&H!2C7+2#.3+GE++;0@0!?E?;3*<#HH)&F,2A(#.>,'+1E??+):&"8.C6%=3A+'6CA;!"?6?>.!(6B<<@<)3=6EB1$
@r7028
GACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAG
+
-"7A*&/GDH*9-H%<9@A9!=F/C.0>&E0<GC;)9#=-*/(-+:76-#,#*/1?:@#
@r7029
ATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATNGCTGGACTATCGAAGAGTG
+
5GABC9>@D(2=1,$-00<'F%8B*7,47;"FA";*(0>/=890-H'*0@$F/-H#)C2&-D0G49D8F.4E&>!EH,'3CB"9E'B45#9
@r7030
CGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCGCGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGA
+
*:>,6F*"@F'&7<EG;-EE,G+.7/>A*7;E0:8B#D(=D)'D@815=B2*5*"C@60D1<#?,'D1FF:.DGG66.1'D(C,&18)6=B?=H*:#(>%5C9;"'8<?>62B*&'/*8D&D(9'*:CGD6#=3?.A=:1>,!%2,H&&1
@r7031
TTCGCNGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTATCCGGAACTCCGGGTGC
+
B+1(*(#B&B%$>G8=,&==?@D+F>=;EE5:G68=5)"*>/B2*/=AD"A1B<9<@65C)B/D.D5D@5D1,,'6(/%4$0>'H$<2)"3"'')E*;50.>2.$>&
@r7032
GCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCGTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTG
+
://D(G#E;!689E3:B*GB,,8"/315B9G5@/=@.#BA3B7>4/9#B>2&?:$D&/5(4+?@GB(FC28$@.+4CC7:>;!H;#7!&=G9)H(?/H$ED'4!)?:'(;12/00=CA9B'64C16C!.@
@r7033
CGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTNTGA
+
?$$',"H<3F396;?8%3?+D.F-#0"34$B63C&6&+".>G9A)(-=C
@r7034
CGCGNTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGA
+
HC-!@4'.$B1%"*%';7)#937-6A(9#-*DDF.-AC9GH:8+,));5(&H>(":'
@r7035
CCAGCACNGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGG
+
5=B;*&68";5B%(6)5B5+#3>4/>=:B66C?H+"6<=1&,=08D/B>
@r7036
TAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAAACACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACNTCATAAAGCCATGATTCAGTNTGCCCGTCTGGCCTTCGGATTTGCTCGTATCTACGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCATTCCGGTTAACGATGAAATCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGAAAAAGCTCTTGGATTCCTGAAACANAAAG
+
6C$-;"<B<)'7BF@;6+#+19:=/-0=.8AH,&3A,@?/<G6#AE!4>&>,':DC6,"??@<:#&*2%(*?5.1G!E>!%'5)=5-@8C(2A;F?H'=A)F6?*9>7:H;A+7$&!E/)C#9$B,=2'4;"9?/=.E+4#?1A(.8)!DC23:#<'4C#B>'D;>+(#@3H:"*<0+)CD:=AG''F+CF%$7+,D9#,HC$32,F,F/=&)00)<>*,!"41$#/CF3@@:AD4G>)802.H/D,;*E9H)8&&E=<<(#4!7-$E$/&G,,+3@DHA<)B2:*G*E>*10?++,-$48,DH@=CAB374CD6,>;3?8"F)#$527,B=H/C,?),;,&5,2+FG+?%6$@,/B?'DBD2!+F!(F=DB%?@"&*#B6/0?).&<8805E61)5B.0<@D749:358BD./*CGE"-28
@r7037
GCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAG
+
89'+E:E1G$%E8D-9.6>C6".8FEF5F!-*-**@G5C#96-"/@%E2H$3B$=#C63
@r7038
NGCAACAAATTGATAAGCAATGCTTNTTTATAATGCCAACTTAGTATAAAAAAGCTTAACGAGAAANGTA
+
!+#*%&(&"&)!(+*%#%+")#&*')!+((!*#*$%$$(&""%($(!&%+"!(#&!'$++!+*!*!#&&*
@r7039
GNTTGCTGTCACGCCTGCCTGTTGCTTGTTACGGNTGATT
+
)!)#;?59BD),D1-/#?HF&#D,'++)-?724300(*30
@r7040
TCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTG
+
B(#@H8$F#;6644F>-EFB<0E?2.=,./?;D14D!,02%/039+E(&8';'A
@r7041
TGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCTG
+
36:GA>4!#<D-%%@1C"C:!<G"E"80:=)C3&CAE7#9?@A4$1>)87-:<C5$G+
@r7042
NATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATNTACTCCAATAAACCAATACATACCATGCCAANTATGGATGAAAGACTTCAGGTAATTGGAANTGATTCAAANAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGGAGAAAAAAAACCGAC
+
!;)805D.26+.H4$#E&='D#,=51(,4:(A)'(/E:4.@B>7164AA):0>4A;-+>/@%C20*&&*"1+#@3(EC106?@?>A%0?&8F-$3C#?FF&5%"-.;18A5/<-.9+62*A8/($)$E07F!!D:!0B>8?.B':/!03@DHD0C'.H5:#?'%<B8C@!(*F!#/0>,8@7$#03EG=@%9833)A./9$;8&'.2#5A9B,+12!C6#(,=$=6"C15?%0
@r7043
GTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAGCAAAATA
+
&BF,=:63="AA(50-A82%FH+>*+E:'/@9$%-)4D44&0=0:;)%C6"
@r7044
GTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCANAG
+
%.*66.#5E/3$E=&4E<9#D;=3,5D5!20E-&H">9?%D;C4;7<<CH$!+#GD4-0&=7=9!%$/220E6<HF.-91''>:DD:;9.#<:@15!FG"E'1:,$A6,B)#-"1G;??03A&B/>2.&/-'>=C602$E3
@r7045
NTCNGAATTNGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGGNCTTACGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAGGC
+
"*(")$&#&(+'(+%!(*$'&$#(%!&&()&'$)##+$)!'$)%!(*"&&#'"#&#$#$&$*$*%")('*!$)!+)!*%#$+!&!+()&%(*$&+*))$')'
@r7046
GAACGTGCTGCGGCTGGCTGGTGAACTTCCNATAGTGCGGGTGTTGAATGATTTCCAGTTGCTA
+
'+/,!!&>:3G8=A"7'A<!(H@+4#E5!-'9<<A!&E%,<1%,:8&&('54F<+!94),**6@
@r7047
TGTACCATGTGCGCTGCTTCTTGCGCTCAATGCGTTGCAGGTTGCTTTCAATCTGTTTG
+
*1F@42/9;#65<)')E$7F';8@"/:9=)"F$=+)D)?)1<)ED)</3.#0)%7?5E*
@r7048
CGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCNGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCG
+
H(;&=3C?/.%%2G)?F!#$#.EE1:25:=?;.&CC75+86H79@::DGCG!-BEBA1*G@'/>@)BD@%>3%>444BA(6!*"6=@?82)@E0G%+!B(?;+7(C;@&&E:<B'0F62C;5>F6$E?,#%:
@r7049
TGTAGCCGCGGTACGGTCAGAAAANACGTTGATGATAAATACGNGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGA
+
**)()$+)"$$%&)*$#'%)"'%&($!(%!"+!)!+)*$$!$%(%"*$'('%&&"+!$+("*&()&)**)$$+$+%%!!(++'+"#")((*&)&
@r7050
NCAACATATGCAGTCACTATGAATCAACTACTTAGATNGTATTAGTGACCTGTAACAAAGCA
+
$=22>>,=A:BC((106B/(E%151A76=,?!8/'&112.B/FA@#BH0F:'7ED-&-EC=(
@r7051
ATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCA
+
6+=!%@H>3!H?=*G""*/&E%%7FB;B!5H2?C1"/6+HH:>0'F%9G:%2@EB-.'9H1
@r7052
ATNNCACANNAGCTCCCATACGCTGTATTCAGCAACNCCGTCAGGAACACG
+
%!#")&&"#"!+&)"$)$!"$&+%+*!(&#&!$#%#*+&"'&%(**))+%)
@r7053
CTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAA
+
.=B/3,A2HD8$?)&26FHGF('D8-<E3!603@A/F*!;2A+.93?#;##:G8>(5;03<F((/DB8H#5*"+)%0$CA7!0BH#-7='H;%3BF$):F+CFD=,"E1(+41(C"#%;"A5>!4
@r7054
CTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATNTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGNTGCCAACCAGTACGGCCTTAATCCGTGGACGAANGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCT
+
=1H,=%F7(3!HAG:0C5!B"-<>.?:H*'',.!F5&6'1;&,EBA#"*-8(<'-:&H+"EH8CF863%:!G40@1@"!AACAA!/54&*G%/5>"5EDD;;>@'84A?/"2D0C<H')/;7)'D:5$#>,=43;=/(*"$CE8B05%H@+)$4*0*F-&B"$9'3(-0E%22)66H78.2?)$?:-2-E.'@<431F-=?(G#24D+)*'0%2+4-E10>#+6D>;#44$A!C)D'.2'/@=.04@A%C:B
@r7055
CAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTT
+
4=F4+CE,:8,+>6.0*/BB!3E@:&<*.&.D-#D>"(AB/?2=2G7%D/%<?62$61,&0-2-$E9E
@r7056
CGCTGCCTCAATTGCTCTGAATGCTTCTAGAGACACCTTATGT
+
-'(17%3G,#5=;961'/,('E70.F/;6&"B8#>*F#'@<8C
@r7057
NCNCCAGTAACAGGTGGCCGTTTGAAGAGGATCAGAANTGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCNCCTAACC
+
!$!)+'%$$'!'")$%*'%)&$"&++(#####!''+"&%%%#)&+$"!%#)"#+'&''%&$)++"(&$%+$+++!$+#!""+*
@r7058
AGCCACGACCGCCCCCGGCGTGGACAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCT
+
:)1H%>H!+($*B&21(38;$.;B4,&%->17(*D7C4CC.?8-ED;A*/10>$E5@2!)5(=HG41E-H4BE'#?BH
@r7059
CCGCTGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCAATTTCACCAGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGG
+
C/6='4C?):E<0BF3+4AC*712D@6A8!@(@A%;!B(DG&'6=>C':C$(D:6>D7@+6/6:!"(=D8?$5<98+"$9/<6$A2).,.49))?7#;62.318.FE!=F+25D-C-)4'&67C:-+*B,+,=@E"63%(%#*!*E%=@?B9!80D)
@r7060
GCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTG
+
(C5&4&=.3&2C!'/AE:92B;<3H=F,C)A$7=,'E/';=5.7$'%!!,=!021=5<H
@r7061
GNAGCCCTCANCGNNCAAGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTANCACCGCACCTGACTGCTCANCGGATGTANTGGTGGCTGACGNTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGG
+
*$(%')'(&(*#&&"+'#")))%'()'+*)!&(("$($!$&'(&&$+$&'#'%()'#+#+$%%)$"!()"!(#"!!$)+'+)'#!"!%")#"*'*$''"(!*!%"%)#'')(")+&%$*!!)!&+(&&*#'#"!%!+%'(%&+%+!%)(*!$++&"("()!*%"#&$
@r7062
GCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACNTAGCCTTGCTCAAATTGGA
+
/=-C35<+D!61@H!2DE=1=>>3+&1:2@+(043?'0B@!!1;F@3!FF59'9%-@@/$
@r7063
TGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGANTGGGCGTTCTCAATGTTGTGCAGATCCGGTGTCT
+
F/4<&/'<C+G/*/+A=)*;#>-:"H.F4<0$7C91E=<-DH@5,1H5;F069.C%'B5>!($2;#$-C3G+)$;:F/FFEH25"C&-("5:4*-6'!<>6*'/E"-6>8@FH:B(1-&DF7+/6"%%#7>':>*6*
@r7064
GNGCCCGNTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACT
+
())&"))%+#"&"$("'&'*+$'*'*!"&*'#%&"!*!#')$&+$*"!%)(+!!%&("$'%"+#*+&")!%()")())+)!#%+*%*+"$("+#$)"'+('$*+"#"'&")$"%()!)+$#!#'$#''*&(&"#&!"+*)**!)*+*$(
@r7065
GTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTT
+
H!)G;6C.&)*'/2/B-//@C#;4"';"A80;>,G7:H<717F"1C,+>(/
@r7066
TGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGNTCACATAACGTCCACGNAGGCTCTCATAGTGAACCGTATCCTCCCCGGTCATCACTGTGCTGCT
+
'C17A,735<,,.'A,&B&E95/35>56'+%-9,=D3/7D<<!:->>6A4%:#>2H<@FF8H7F3,=".#@5.)6D>.31"75(01-:H4&C=8.)-B'7=0:27H#2>,1:A$;?7,+,%%H)0#530"4EAH
@r7067
ATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTT
+
5.A=>=;+2C$DCG1/"%<CFE.D%(%G>6B!(78E63,;!>$'D/?=@#/'5?/:62BC;C'-A;$".DF;#7(=4,@/=*@G+:7+277FA>9F<)1#
@r7068
NACCAGAAGGNCCAGNATATTTCNCNAAGCGTAGGGAAACTG
+
$*%*##!**$!'#*%!"&($#!)#)!'!""+'(&*"!''"%"
@r7069
CAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGNTTTCGCTCAACGTCAATGCAGCAGCAGTCATCNTCGGCAAACTCTTTCCATGCCGCTTCAACCTC
+
<5%7A&G&8-=9-D-%>5G,<F,8&8<5%A#+;*,:**.##-!EA!%'DCEC<"-$E7+>9-/%"::A92*0D#&+4H.#">1A-H9%H,1->D/9>+'+%A,=A1G5#2DF@-A3C<H6%B:.,G47'3H""78G.FB3<+'
@r7070
GCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGATGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATT
+
7:7&2?880*3D-H969F&F:$!$!=4&=1(%/B7?((4')@7'.7F@;H5/+C!B76!;"@#=B1=)B+#3()4-61?9/)%*9G:/@>+%B#F
@r7071
GACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTG
+
(H::>43##&>#$9.C&8"%!1#+:G&483H7%0><9;0#D+2?(B!&F"/<;8CE#07"CC'-G,=7/3+(/?-3&+(9)9CE;/3A(9<G5+C7/$!E218:%><'&??)?BC/-9.;)*=/%*8
@r7072
NATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTA
+
+$!+*)""$('!*!&#$*!*&)!%$*+!#((!!$"#($'+)'&*"$#+"#(*')#!
@r7073
CAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAAC
+
<?"=0F4@%6;34,<"/6&<;$/#%=(+:(:62+4#0'?B#9<$1=</;>1!<19$#<917>-'0#B$=5>'A37-)+4#+8B2%3%44F'4B$@@)H*@53,H?&.=-ADF2&DF&92CCD6&H13%!;'#6&7+;ED)!,C6F'CA.A6>H+.E@(76(H,),-";$"!?&61
@r7074
GAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGNGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGGGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACNGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTG
+
;%$"2(*1D#0,9H5;'H7.*0A#="-<.<#8"+)%:8(:$6)2F.*??,(B2;3.67@DB:))96)3CC'$'$+5C"C4)'1"4)64HA$+$(F1#-(0/,!F/5,?C"2%2%H+H'*9);6*1+?66+-C(:69C-:4/6->?(0%6?=BAF)&$@<61@7!&,%6/FF51@%?4,7BEC&&4"*12<#:CB+,/:&HB883*>@6<AB+$G%2#='9B$G@#H98A,1GE2/,B,6+EE?0/)C-.H5G&!B/-4!%.9=(+$H/,4&&B%/17%(<&+D;E;7=9&,"C*B2;9AA*$E<E=+.,,$033E@)#9
@r7075
CCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATNCAGTTCAAAACCGCCCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCGTTACAGAAAAAATAACGTTCTCCACCGACCTCTGT
+
2@+@!G!&-*H(0$#27&48,;,./7/</=$*6+9EA.7A:E>:$E&G>5)@,A99*A$=*@G(00%@?(G<$91,,:!%/<*>(?27B=6<9*&D;H@C=D!C-!F.C'BD5/6<B'(!G)>*7'07<E0:B$&"!05D<%FD50GAA'-)"-@**2;(!C2B&?"*B308;B8*:<8</65$7)@5(;-&H::6E*$8@35(.5(5)+?2FDC<-$
@r7076
CCTCATTGCGTCGATTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCC
+
F=$<-%-1+(:>3C(F*0G8>9H-A.6D0+90,HA1.(H/:HH)5>!6:@
@r7077
GGATCTCAGTTTCAGNATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGG
+
!'/,&47%;"?#7:5B968&$6>F"=>18@8C.>4!=F!.-A$+BB=+D;*3-/*;?9:6#%$@;B$+F;?$'A#,4F%*>$<1G9"E6(3C,=/?/!D@!1&+A14#GD9F"EA*3%*<!/5)-;2;25#F:3
@r7078
NGCGCGTTCACGTCCGGCTGCGNCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTT
+
#A9*-'G;3D$.HA47@C.D2>F)#E16)*>*:4/C2A7)(E8-"/FE:6E87(4H$>E.15@./299G&);0E5E8$9+")DAH(32>!?EBC7+H01:2)=F20+AH"(1&);3'CD8&#"7F6,8>83,?178=G4$'+#/<.
@r7079
GCAGTGACTGATCAAACACGGAGTAGCCGTTATCNGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTNC
+
',9;*"925'+BE=B-CG;F(%3D6(EH$&$&D/(/,#,D$C&3A5=.(;891-G,4@#>B%(.>(59+*H3--#.&'?B8%3=35C.+,G&;#
@r7080
CAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTAGGCATTATAAAAAAGCATTGCTTATC
+
4"'';76.#*!#/%<&$!"/9%=.+?760-8.&#H&4E625#2&)DGH,FF2&H@;/(#,?G%='-5+:<=%#F$2+4?':DE7"19AC6=4/4)'
@r7081
CGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTT
+
#5(@&G=-?667#<80?#4>CB/0.)CG<1.E<H=01H>>5%1/-
@r7082
ACTGGCAATTTTACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTA
+
G8("7<:<"H=DB#-D";DH@:/)"=2+0B>7=?/4H)17=="F)$42=-.-D;!,/0<:<#+954.%,,-+>7.<=;FC0(3H6,&,?%938,CA.90%4-$*3'%?D+B!&8*
@r7083
CTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCA
+
<E9+4:)6(3!3+0D>$)7D(GA-'&D7;1/<HHH-C:F%".FD?9?9?@(BE-(A,)#EH%+H.GH-9!).>=@EG#45'C>7-B&*&=->5&HA$=:-1%B6=)8)B8%F!&:'!87G)?4H">F*.94AA=%D:8&?>0=->B(.
@r7084
GGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATAT
+
)+!(')%%#!'((&++$())'*(!)&#($*'*(%#!+++"#(%*()$!+&%$#**
@r7085
GTGAGGCTGCTGATCCCAAGCTNGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTAC
+
0#2G3.2?9E;?EE#95'0<.AFF1#BB("9C4978GFF29EA75<..7$'?3;5F)G+==-0<(+973%$>>.'HB:9*9).#<2@8$2%>:@%>-/?E21'#DG2E0>?;
@r7086
CGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACNGAATCAGCGATTCTGGCGCAC
+
2H0GB!G?-0%,BA?F.4B("&5H1E"!?.?=5@E7*9!;H1#?A*@"?:D.(5HEA+A#5&6:*0=*&A-8-,'8-/B*5F($
@r7087
TGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCNGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCAGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGCATAAC
+
7=E-F3$'(+4A;2/%##>D6+80+2(F6$83/>:E>@=!E"1&(<@3:(='.:G47%#B(,'773EA+49AF!+!5??+!4);0=)*(.!!))#$!BE/.30FB*"4D$:#?,(*F#+,0:+2@;*CB(-E&%GG":/;;4)G%@,3E$3EF"&;D&3&D42
@r7088
ACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTA
+
9)6,"DF$*=,<B8E+DDD.?2+9+H7;;F*>D:@;6=4@.!C(7&>7G;=?B,EG"?C8.
@r7089
CCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATNATTTCAGT
+
F<2>85E4/G1)<BEG%>/-,=/)>>5>+=!75?36",&-'6809:A;5<-*B:'=48!4<
@r7090
ACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTAC
+
7'!"0%G,=E!1E7D<>G.4)7=(72F'27;57<EAH3H6?4.(4C$HB%C%9",>7'%$:
@r7091
TGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCA
+
"9:)&25=;>9"A+CH:<,..F;D,,D@<H7,,/'181+.<;H?$6?5%4.C3=!$=DA"A9A$E$F&7D=!82*54D)!#(<C7@3HE),B=6;/@7
@r7092
GTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTNGTCAAAGGGATACTCGGCGTGGCAGATANCATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGG
+
B348<@*51EC//D%1,/!.>51D2(DH5!;)2H'B'*H+A*(@C@5;<#/C6@0/.3E$!$&FH)A-(4F@-?G$G*'B.3-9A$(&')7'9%?0=622G4+?<F62)H27%%AF1@%>D$1$
@r7093
AACGCCCGGCGGCAACCGAGCGTTCTGAGAGACGAATCCAGATGGAGTTCTGAGGTCATTANTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATAT
+
*F94G+)DF&A:5,-'+,A:E4BADC<C8-:.3#:#;!@=@B%-'=*@C6),!H:'-65D4(1-5.:>GH@+57-8)2$%CG.,73('@2B)H-8F6FA+ED$B;7'4C.;DH%H<D*9C?=C/,9;$H?3H!@$A0F#*,(4*55A?%?=HG+:F<1G@96?7*E<):9=D1>>79A07:190A-'F>
@r7094
CTGTTTCCGTTGACGANGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACG
+
#*<.#5(C:F.G"$59(0C(;@"73#3H26?H=&04H,E");BF&/2@8:9H'
@r7095
ANNCNAAANGNTCCTNNTNNGCGNNATACNNGCGACNNGNTCANTGNNANNNNNNNATANNNNANGCNCNTTTNNAGGTNGTGNNTAGAATGCNGGNGCATATNNNGANATNNAANANNCANTCAATCNN
+
$$##$#"$!$#$!!"#$$$$$!"!#!$$$"!"#$""!##"#"$##$#!!"$!!$"$#"$#!""###$!$#$$$!!""!"#"!!""$#"!$#!!"$!$##!!$!$$#$$!###!$$$#$"!!"$!$!$!!"
@r7096
CTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTTTTGGCGGTATATGGAGTTAAAAGATGACCACCTACATTACTGAGCTAATAACAGACCTGCTGNTAATCNCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGNAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGA
+
@$G%!>3F!(D--5:;0*&9,)32!<7F;A>G.E2AA7#'71.>%7<%!?!5.'9+G36<.;1A=B.@7H3@3250:-0-1F4+<G,E0B-3%.?-(/!$G0;%!3:>+8'5+.##,<0;3+!4>:7,8=C*1./+G9H=2B4!B(7$27@.G;&=$<(4G?%:;;8B<;@46#?@?&:/H>897'+0:6/<'68$0,+E;(8'C'<$%'59)>0545G7,,@+&G(>"&"/0$!#E$8F-9<$D;5F!.CGG.C5HH-0:""6CD#0<).>-/@5BEG1:$AB,'.@@(B>;)#-%,=.67(=.#,#3E(?;<4%G%!.*9'4%+115,"3?4"3+>4)%$!"=%A66B*=F)A#491)$"8@EED.1#0D-#F2=7B-7B?%9-#+#'3<
@r7097
GTTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCC
+
!,99)-F&1'2"A$AB"!EF,>5##(32'D94,G!/F63B;2)%&%<GD-6-#BE3&E*,,+%;=4A/+"2:@:7/,A
@r7098
GTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCAC
+
17.;$,8/"2'/?$1'!"-:D,BF-2-1=H*C;3=A+12@;D6"*91%/.&'1'+D>68!;
@r7099
CATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCA
+
3<&.+7"1#*0"F,9!51;@/,/GE/B*"7/B4C.9174,=14*
@r7100
GGTGGTACAAATTCTCTCATGCAAAAANTATGTAAAATCGGTAGCAACTNGAAATCATTCAACACCCGNACTATCGGAAGTNCACCAGCCA
+
++)%!+$&'*+)*+#+)#%!)"(!"%(')'%"**)%"$'!'%%&&$+")&*(&'&!('!%%)%"!%)#&!%!'#(!***+)*+('('*&$#
@r7101
GAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAA
+
!4H<C0D>?(>=490:,*>$/E8318%=B4-CD$;2"E=E=?DD".B$!3#<G>%46-8
@r7102
GCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCTCACGAGATACATGGTAAGTC
+
0+GE98DG#'?15C6<<H#.&$/).?$12?*5$"/>/C370$,$=6F?C>*-.;28'G#:5&A5&74F6'6GF=@E$
@r7103
NTCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGG
+
">8G%7!6?(5E++)&!#A)26C'EAF:.9CF,:F=B54C?$;E7A+)A;8&FG%&":5,./&CG;.'-<()'*09>8'77:.@'!:
@r7104
TTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAAT
+
1A@)->@5""-,)H9@=3+5%0,6,9-%:$G/(:"7$::9.:;CG?$F'.!.>H+-
@r7105
GNACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTT
+
*(H>+AE7D4!A8"($/5EB-F#"")EC0%%,./==?@8%@,0!4=/C(;9B)39;%(4>,BB<@4
@r7106
CAAACGCGGTCCGTTTTNTCGTCTCGTCGCTGGCAGCCTCCGGCCAG
+
F*9#2D1(9@*EE+>06,D#E+E?B'3,.D#%,$;"/6'/9F@*/:<
@r7107
TGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATNGGGTACTGT
+
5,?2F$6C)0.'@H,.0*+&D-F*5/+13;@9(,>-.':C58E8E/?C;1+='E676'D?%3F
@r7108
TGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATNTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCT
+
(83/HB*+'B>-7@)!/*'=6#D%B%4CH>3BHEA)0C('2H;2CDF(?',AA..!$22$$&A2=A$9+D48(>94$&B0>0G%&A#@&?;+93921+EB+%$>7'CG8/.='D/6+2(B?93-?>=,4,*A66"E<@2'G>73"5'8$FD?(3@,@=8B?C&44F>=?("G=:194G4>B=1A-$=6?25+0&@1<,*"A#A(A'B3,2C3;>6450.%7>+,*7:$CE611(E;D0-4C-"G(.';F96;6=,F.,"6A*$F%@'9D3.'6-!8>@1;<*H7-'
@r7109
GCAGTNTNCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGNACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTNAGGAACGATGAACAGGAAAAGCAAATTCATCAGGGNGCTNCAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGA
+
'''"("*+$%'&*%"(!!$$&)+(#+)"%(!%%($+!%($#&&#*%+&()%(!$&')$%%(($'!&''#%%"%!"()($+*$*(*"&)'&"$&#"!(%+!#)+&(("+$%&&('**!+&%"!#$$%"#++$+)""*'!)#!)"&'$"$))+*%+#*&+&$*%'"$+&+++*+*%!)+)#%*)'!(&")*&$#'&(+)"('("&+%!')&#&++!+)&$"%%"#"%"!'&%))&+'&##&$"$#!&('+#&#***))+
@r7110
AGACAGAAGTAGCACGCAGACTGAAAAGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACNCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAG
+
=6!6,@4),$5*9'"H:!*155,@1,+-$:@7H7.<,A/HD.7"72A--";=F)4C.03*?E*-$7*B/3-.@*&E.<'9@6"#*D/0A(2;H-():<=E;4=63F1/%7%:0G/@$$A!?6FG0+:?E8#E8#A<A&'G'%:@E3!0(BDC7F/&4A04!
@r7111
TGAANNGTNACTANNAATGNTNGGGTTGGGTCTGGAAGGATTNGCTGTACTGCGTGAANAGCGTTTTGCTGNTGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGTCAATACCCGTTTCATC
+
)*'(!&!(&'%%*$%*"*(#%%&)&+%)+**+!$)$)!&&+(*%)$'!&)"!!)*&%*#!&*'+)%")#+&*)#%($"!%"'"$$"&*'#"#%"%'!#+&&!%$'&'!"%#+&%+"+"%+&)+%&$+)"+(+!'*')*!!"%+*!$%+"**)&&())$*!&('*!'$+($+$#&#%"'++!#%)&"&+"&%"%(""%$(&*)"&(%$*!*!"!)&#$"!'(%)
@r7112
CCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACNACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCTGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGA
+
',#C/)7(F9*(>9/EH"GGD*/008F7#;#&+39"!*7+1D*GHF!*.<*6.4F)?"?@/$?%4H/5/69F#/2?3<BA8'36B2F#1*>#2*4GCD("2@:.C<#(</)7:F@3(&;87%9=G&8!BG7FH)?G<4+8D-"0107!$A.$.$+E$9!5(:);2-&'AAE>,!;&9ED';0
@r7113
TTTTTTATAANGCCAACTTAGTATAAAAAAGCTTAACGAGAAACGTAAAATGATATAAATATCAATATATTAA
+
0'<3:)F)50GGB4<E$$:G01>D?4;/'&>E,>=@9'=H0$*1-&;+D5,B"@8%"#&-7+$**,$B8C)F9
@r7114
CATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAA
+
6@DD*-D4!=+*+>18+2/E1(;&:@>GH-$(##)'!4?E,3"?
@r7115
AGTGGGTATCANGTAGCCGCTTATGGTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACC
+
@%3$.D@20:,E52E=B9H1'>*3:.F,4%/-B7,0=$6#3)@&3E$;$,4<<H<C#!D;A(!;H;"><#A<81@7&.5"E@C6@326?<)0>15'.&F"('-+;"*F(G0(G
@r7116
GACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAG
+
?!+;G79D46H$C>5;%/2$D/?2H*9*%/ED66)</4%'$<,8,&G1E:*'16H4HA)0A+5'?=%$6:
@r7117
CCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATAT
+
<9G;9@0038H)3:A1=09BH$3@=?/5=C7#"3/)C;!A.!9HC9.28<"8;G?G1F(6+((!1:81=#6'>=4<87A'(2<1,!D'H.4)5AE.74%2:>+>,B1C.3CA&&;(8/%2
@r7118
AANGNTCATCAGNATGCAGCTNCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATC
+
&*'*%"(((+&"'&#)%)''(%*!%+$()&!)*!#"'*+%"'"%*(&+$)')#(!)+!"&"($%$*'+"&**(
@r7119
AGTGNCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTNCAGATAACCGCCACGCCGCATNTTGCCGTTTAT
+
%!'+(!****%#$!(%*##*"'(!#+%*'#!*!!!#!+%)%')%%*+(#*&&*+*#()"*%%&"&$!%"!%+%*!"+)"$!#"%
@r7120
CGTCTACTGCTTCCTNCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATANTGCGTTCATTAAATCGGAGTTGAGGTGCCG
+
(4&E>*G/)E2B$#?C.'F&,*:&2D>,/G89B5*A30/-BE*73'!:)/F#5%F76!6E?()2&3+$G1%@.2("0%3(8!F.)CAE44-<!9E*??$H%4+/A7!21"F")1?3!1;$6</@9;:HD>%5
@r7121
GGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTNGATGTTTGACATCTGTTCATANCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGANGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATCAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAANGCCACTATCAGGCAGCTTTGTTGTTCTGTTTANCAAGTTCNCTGGCAATCATNGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATT
+
'DG+2(54HC1$/9?5B@G?8H>"B3)%AE-9,;&#?EHG51/;0&?F2A--<%A55B?5"H-)C%,(2038"&(?<08/"+6"-/H3FB)F9-;A962&A"(#EE'*9G9?':)7F-,+!8=E73)E")&(;H6-237'4F&%'E!5.3"/='*CE"1$%/A$B$7%<H:,+.=A!3!")3//2;"&9A4283(-/AE4:0%$D?2<9&<6GFH$?2+302<0F',;9G&H@DE27<0,0<9>*>GBHBH5AH#2(565>D766;6:GD==,37@8H;4D!&,,A*/"B-1+B#054<9'3)?1!+C#)GE-.A.449-G=@,%@C::69#0&/9;*<?:1)$"!@B3G9-@E!!6+&;B*4?C!HF)4DEF.C<2H#7&;8A
@r7122
TGAGAGACGGGATTTNCGTGCATCCAGTGCATCACGCATGACGGNGATCGCATCGGTGCTGTTAACAAGT
+
<F;-A'?$+47B(>&5&"(C=6@A<86+#)?E#?=AF.@!H.D%%2:##<!G@"D:/3$++5.EB6.9H,
@r7123
AGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATNTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGANGGGATAGCTCTCACGGAAAAAGAGAC
+
B?*(,>!>6-"@D$#8$'38D"@:6%/G8)!1C6F<B)$H>:8,'FA+@!.G(+5$=%=?D#C&D)')C,E7*:?2C/%:,&)G+7G(5H02C+""FB52,B=4:2?,$>%?&1-,*!@C21:H7%4;D3(=9-</+5*-
@r7124
GTGGTATGGCAAAAAGCACCGGGANAACACGCTCACCATGAAGCGTTTCAGTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGC
+
&/DA.8EA@3*!9.'<4$"599+D79GA)-5*G(&3;"*GB?A'%C0=67(!'A"&G+FDB*G;*9!,E+'=)8..0BD@3B"1&/?G:3
@r7125
GTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGT
+
(H?.4(""$(%#>HG6,6$1H%A)/>E#D74@B$D<8F'(#=3$#004>B#.(<53;@8
@r7126
NNCTGCNGNCGGCTCAGGATATGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTNCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTT
+
"($'#)"*$+**%&"(+%")'#''(!+!#*$)&)'('"&)+$***)+($$(#$+)('(&&"#(()%*%#'(+#'#)'&%#""!"$+$%(&"($+%)+)&*##
@r7127
ACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATG
+
+-D1-E.AGEA;F&,0,(93)%057:EH7?'?+!C.3/C17D76.9C/!2@/
@r7128
TGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCA
+
6@,81=@'?.>+7E3"#B#)@A5&2&(H4*<A)/"=28>6;,?4?@88H793'08.*H/$'*(,;96G!"998:H).)(179H'-70-6,G9+!1%=%)<*"*EG:@%)*;4;C@GH6F,.;+@(.1(H.;G1)E;05<F>5;(&+*2+
@r7129
GGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGTAATTACGCCGTAAGGCCGCAGATGAGCT
+
D73-B8/46!3DDE55*1,,6BE2E?-,H/H@0-*5A;-07+=/C1!+A""+8HE;(BE2!AH&@9-!>=)&D:)C?'/?GG*C*=)/5CH&)C@28?)'7D&
@r7130
NACTTGTAAGCNAGNATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGA
+
$'%%&"$!)'*))'%'(+)%'%)'%'#"!+*!+')$$)+%%!$#"%*$"+**!%($++!'$'*&)+'"(&)("""'&#!%)*
@r7131
NATNNCGGGNANNCTTTAGGGCCATGTCATACNCGGCCTTCAGAGNAGGCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATC
+
!''!&$%(*!%%$*'&((#)%%'*'&'*&(%+$&&''!%!)"!!!$!')$+#*)#'!("$((#$)!'%)%*)++)*((*"&&!&!"
@r7132
ACCGGCAGCAGTAGCACCAAAGGAGACCATCACCCATCATTTNTTCGTTTCTGGAATTGGGCAGAAGANAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGT
+
*$)+%))#'$)(%%"$$#$&*#&+#"$"'%&!*'$#%*+!&"""**#"!("&&(&(#)!%)&)(!'!!)""#")"!)&#&+%&'*#&+%!)(%**$)!#*)$')$'()"))!!"
@r7133
CCTGCCGCCTGCCCGGCTNTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCC
+
1CE)-!?A8>3!,>E)?::3#=:-.$;-->/:G;$!<!'@B;)>G@7!&"-*08.?,
@r7134
NGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGT
+
$*$C&(B6&2E,F+?4:&:H65(G8"9<.053&F5;6C8++HG(42538>)+H-(E;*;E,=+B;5/&/;##17:2B1?2@6?!/8;8!$%5"""/
@r7135
ACAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCNAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGNTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCA
+
&%=&:(8BC?=7"?-#4;@9F$FC"-@C(?<H(C'+/5!5@>.*A&,+"6?:6286+1>974%*2.2=@,%%7.#@>7(BD>H?#G+">=2#ACD#3(3:&29;0BAEFE"$?>,),>94&4B#,<0%F'!@E&>:/+".,0+F=F)#=><)-?+6C96H+=1D5DC.>,-(8H!(D<+77H5:;=D>'),D)
@r7136
TTCATCGCNGCACTCTGGCGNCACTCCTTAAAAACCAGGTTC
+
EE+$65:F"B6$>:=D8*#0H887>F(5,=D69+(>@4#%E'
@r7137
CGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAAGAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGACACTCACC
+
4>%H*:(!-7':&)2DGFB:7B)!G1(F8#+@2&D:GH/C#G>4E:.!?.=9&C@"C%%HC$2'@7/0.&),0"'+F6#;:6/(EG80C6@;G<3/5;H0<=+E0D63$GF5)?:?/6.-=$E=F?42BF7;39
@r7138
ANTTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTTAC
+
*#EHF6/;28+$#*(0*BB9&91<GG7:F@90C)52C<-,&%08:"4;B<H16.E
@r7139
TTTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAA
+
$"/25B8A0F!./=+*5-3@+&(H$"9840H1A86-C/:5/C&#-!(?A*"=8/<.A!'>;?=C$!==*'*962C;6'2:--8<A8,>CC&+'*9HC9,A#G?.
@r7140
ACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCATCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTNCCCCGTCAGGGCT
+
E6E/6E,8&H25E%&9**6.834,.'+.+:<>.!#-<4"4C190HC!2''&.*(B4E)G"H)56H1'!29"+,.@@D4+#>5(3#/BF6#&:C"*4B)+.E.92'%*?EC2+)&:=CF3D#)CE-;*:1@:3<<)H.8.#E;1580&#@:H)''%$.F<'5;G<HE3@%A>=2*
@r7141
ATNGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGA
+
('$%#&+%"#(+%"'$$")#$'!$)##+#'$'"#%*"#%+''+!)+!)&$%#
@r7142
GAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAAT
+
?F>&=5<*&@5#2+#('8'H?"B-A'))C;#=E$C924+9(#((%%+71:1.6(35DA6!%,2.$:12:'0C
@r7143
AATTGNGNCTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTNATGCAGATCAATTNATACGCAATATACC
+
'()&!&""*+*("'!"*%(*)%)'&%$(%'%#*%+*&(*%!'$&+'%!!(#)((!+)""%#(**($'!&%"#)(('"+&
@r7144
GGNTNNNNCCGNCACNTGGANNNNNCTGGCNNGTNTNGNCNNGNNANCNNGNANNNAAAGAANNACTGGNNGNNCGTNGNGNNNTCCTNCNCNTNAACNNNANANNCTATNTNGNGTTNANNNNNNCTNNANNCAACCNCANNCGGNNGCNNNNCNTAGNNANGNCNGNNTAGNCNATNNANAAGGNGNNTTNNAGNANCNCANNGNCTNNGNNNNNNTGCNNNGANNANGCNNATNTTCTCCTTAAAC
+
!"!#!#"!$$!##"""$"!!#$$!!#!#"$!""$!#!#!!!"!$"$"""$""$$#"!!!$$#$""$#""#"$"""$#!"!#"!!$#!$"!$$#"""!##!"$"$!#"$""!!$!#$$"###$"!#!"$#$!"$#"#$#"$##"$$$#"$"!$$#"!$"$""$$$###$$"$#"$!!!!##$##!"$$#"#$$""!#!!$!"#$"!$"###"$"!""#!"$""!!"!"!#$"!#!"##$"$$!$#$"#""
@r7145
ANTGGGGAAGTCATTCAAATCTATAATAGNTTNCAGATTTGCTTCAATAAATTCTGACTGTAGNTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTNTTACGAAAGAGTTTNTTTGAGTAATCACTT
+
-"75-)$&#.%GH1";%6=/2-@!FEF*<,4=;"++-+4>(3$,8-$2&//D"*@"'8/:+AC+0#,@3+(5534E=B?>6=;>)?-'=-,*5<%-+*%<)=&'1/D4-1"++<F'41)ADE..(!-;3B0*%7
@r7146
GCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTNACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAAT
+
,E;5;$)CF*22-,*GFD&/%G()?8G"*@&9)$0+A.,/0A4A2,H,/H3;>@+5HB0F$EB1;=0A;E3'$03+$)EG9.C<,H<,4&"/)EC6BBG*//$#)+0/+1G1*!>F9?:55=@6;
@r7147
GNTTAGTTNNACNNNCGCGTGACANCACCCATCCGGTACATGGTNGAAACCATTGCTCACCACCAGGTTGATATNGATTCAGAGGTATAAAACGAATGAGTACTGCNCTCGCGACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCAC
+
'"'$()%(!#''$!!)((!&#%)#(!"%!)&+$&)'+*##!"+(&&%#&!+!*)+((+%&+#+!+$))&)'#""!!$%$"*+%$*"###*")($")'(&#)''!'$%&"%&'!**!$)"'!))*)(*!+"("'&%$!$%*"**&("#)%&%)#*&$*#*+!"&"))$*+$+"#!((#(
@r7148
GGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTAT
+
954#5@>E&,)#D'G"0:1-"H..,==,E??=#F&(."*,5"&.;0+1'&@8DCE9?&E>E,=+B+-5/:)$76$54@&=&@36*,.%52.5'-C><(H(?=6/A".!H./E<?2DA2>+&F9@G!:C4'H<D@C.H1:CH&'9?.
@r7149
GTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCG
+
,2%C<#'4E5:AH&>"(8.FB=3F&C,4*75&2C(#2!+:CE%+/!'13*19E7
@r7150
NAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACNAAGGAAGAAACCTCGTTGCTGGAAGTCTGGAAGA
+
+&"'+'!'$''&'+"(*'')&#)"'++!&'&&'##+!*'(*#(%$"**!!*)$+*)&&()&)'*"'+$!+!&!(&#%##+"$*+$"&"%)$&$$&)#("!"&+(&$$((&)*&'
@r7151
CGCAGGAGGAGTCCGATATGGCTGAACCGGTAGGCGATCTGGTTGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACA
+
C>8-F1&A(-/-.:@A/?-A%F/0.=!(8CC!-;B0G/=;@+"-**9:>648F#+'1D8/B#+/<-!31'81BH;5+(75#!7E='G@H4A*:4"GFHDE/<26E1&.G:@DE)*5$)3EB!8:+8'5.1BE11=7,*F/H&>G5%3(('1#<7?52$'G!2E+-BB$4
@r7152
NTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGG
+
"BCG(@>@8(5!<*.HE0%=,+!:*5&.6.5!$8/'2)"!++6H-*4@
@r7153
NGCGCGTGGGGTAACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAA
+
$72'3%67=H3$4&2(#**HBD52G$,F),5=@%)&&(9!@:,1H.01>BD,H"8.%1&(C-<126;=@7+07?(/?9@FA*>5#'C<%.?/0$1+BFB$*7;BG3>9<3(%G!/B"%A16B;1;=(C-1C"1@AF6-?6B3C=7?B.87=!.C3FF/5.F237;!"(AC!/6@:!A)51F-FC#>78:>@CCG=/=*)!H#E":24D>9-%874*EF+5C'8'?$4$FD@!D.*4@/HDG6"A=*,>"4%/BG?770)1-63D/9!.D1B-?*!5
@r7154
TNNNTNNCTGNCTTGCTTNNGNGNAGNNTNNNGANNGNAAG
+
"""#$""!"$#$"$#$#$"""!"!###!""""!##!"$$#$
@r7155
ATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGC
+
D=?CG+.3->@5&0".$#+/'*2-B71E(!"'B!D:6!<<)@C7B#=>AH"0*)7=G62.+(/1G>9EH0H?+4D)B'$8A4C.0?/!*:.>$;@%>19'8FH0+&@80*@G/(;%<$)#CH:((E>3,!/0''--3!F/2+FC6$A3=E$.-82@?'(1(<#
@r7156
GTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTACGTTCCACTCCTGAAGTGTCAAGTACATCACAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATANTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTC
+
/#--@F(B+:F#A+"7B<H.<&E%(>=,E9$9D("4F33#*1'7?0&8C<139#4)(.B8B--+/;@1A%AF=",3%&F)*'")5#16>03:=8'CG?44@-D>FH#89;,<2B:EH%;85E;<;+#(9&:B-%C";2)A%:1?9);:=7FC4B*C%=;('&(?;-0C14.94="$,46,3#;F%555H7&8"8=0F.C$#$!,';8H//=(E08#0!:4<3!>09*5,!*,(!!->>'>##4$=9A0;#"76-@35"2?6-A3H;9(+E7D8)8A0%886A1!$1&,HF.@C
@r7157
CCTTTCCCGATTAAAAAATCTTTCAGATCGGATGTNGTCGGCCCGAAAACAGATCTGGCAANACCAATGGTGTCGC
+
+&*#(#+#!##'&'+"'&'**'*&(!#%$'&!#)*)'*#')()*$#&&(*&$!(&$#)!&%!*!)+"$*#!)#%'*
@r7158
TCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATNAAACGACGATGTGGTTTTCNTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCNA
+
")*'%+&))#*((#((&'+($((###!'"'!&"'("%##&+!%")+*#&&$'$+$+!%)!&&'$!(**$%#))&*$%*##%++(!%)!'$*#"+$"'*(''#!%($''&*"!!&$%(!!#+**+%%
@r7159
CCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTNCAGCTATCTCAGCATTG
+
4H'@@#E4$=D3)1+9(GC6&*+.=%#H2(3D8:?1,+*!%::A;A?/2%@<B>1#5C82=)8G7E)!&63@)C'27#02);+)
@r7160
CATCAATGGCCTCCTNACCGCTGTACACTGCAGCCTCGGTAT
+
'H*9"C"&1#:A"$HH'H=&<,@14F*07>/8F*DF=CG.5%
@r7161
TGTNAACNGNCTNNTNNANNGGNAGNNAGGNNNNGAAANACN
+
"#!#$"#"$##$#!#"!$"!$"!""!"#"$!$!!$""#$!""
@r7162
GTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGT
+
&*4>0=<-;0:,=8(8686(D"#(C2H,17@F(D54==;'=:E7(@4:D.?>E$D,AH#&C&2$#+!.+?#G??*!,G4#"-E8%";/-81$H=!(B$!@+<F!D1@90'.@(,!171<;4:,:
@r7163
GCATCGCCGAGCAGAAATCGCTGAGCACATCCCANGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTNGCGCGGATGGGTCAGCATATC
+
<:!3*"3F2(;(D<(61GE'GH;!+G0*G"'*4:79!,-?09D%>@%9GD)-#2&"E"B!C4<8A7*B32.6D3$5#:-,3$8)6-F,1%A9"+7D4#("*(1&#D@%+25'!#"5HD8'2?)1=&G;9&/>8DC<H8;D6;3E-6H5A#/F&55=)4$A6%(42<)F=&3@24/#"25>+1./@.$GFE838&CC-%1<@%D&&(:/
@r7164
GCNCNNATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTT
+
%$$%%!*$)+'+"#!(#)""'"('*"&*$!(%*#)&)'(+(*$(()%%#'"#+%%(&%
@r7165
ATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTC
+
B,<&H-"&4G=8+2%$*(F->#+?6D-5B*4!G84>B*$9GHA=>!&36D>-)DA=9
@r7166
CCCTCCGTGGATCTGATTCGTGNAAAAAATATGCTTAATAGCACCATTTCTATGAGTTA
+
=$(CEE*C0",H.B<+";?@1GA51@#B(+:0=#E<AC!"58:175B3=0/165!1ED<
@r7167
ACATCTGTTCATATCCTCACAGATAAANAATCGCCCTCACACTGGA
+
$,B#@":8:H>1@@%,)=7,2'/H!F2,1A?/64C!""4E@?4'*#
@r7168
TAAGTATCTGCATATGATGTATGACGCTGGCATTCGCATCAAAGGAGAGNGAGATCGGTTTTGTAAAAGATAACGCTCGTGAAAATGCTGAATTTCNCGTCGTCTTCA
+
53*=H/3B16B@3A=/C@G'E#3DG9A?DC,C/5>+'FH-5B15!0?;8(<"=+H4!5.H)3>+05D->E53."F,@/?/75:#&?E0(2C=!EG"7.B2%(<+:<1*
@r7169
NGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGNTTCCGTCTTCACGGACTTCGTTGCTTTCC
+
"3E7A$.*F$!G4>37B7=&-><977AE?G=E;*+@*A-'+?<6%29C+A+@@7H>H%9:07/"<,?C#@B5'2.EC0&,<3=3<
@r7170
AATGAANTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTAACACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTG
+
#+"!!'''%%'"&(+#+'(+"$*(*$#!(()$(++$"*&''$"$$%$%$'")+**%%+)"+&!(&#"(('%$#%*'$*'#)%)'+((*+"%"#'"$(%*'#&*"")*''+#+&+#$*'&"*)(+%$!'%!(&"$$'$'#("$
@r7171
AANATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAAT
+
=(H0,,F<:A=E:/:G6*0+75D@$&FA+DA3#3,,:7%E%FF=H2&?1-6
@r7172
AGTCTATCTCTCACAAATNCCGGGACTGGTAAACATGGCGCTGTACGTATNGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGA
+
D::D>F.G5%EA76::H2BH%%..&$-8?@+:":B>%H.%:>&B8D??.%4A4=**C'50CD*(C:1;D#@$*CFB8"@#5)90(+'>+9:/*&**A,:D%+1>H)3:A2D7BC-
@r7173
TTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTG
+
4@,,!>A%/1;$3)=:)7"*CC4HF87#<4E(-69'8/5&A5#32B-29&9E/:=)%!<719-CDA7#6A%4)(?/5G"B-*$$AE52D3;'C7E/GA(=%5@"E*2;19+$?H'6=,,F!<=-4.'")E,?(5?6,:3763!C@7&F40,<*+6GA@@E7HF.B(50)E6F%.=$C87:D/?A
@r7174
TTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTC
+
EC'23A99"G=>8B@0$/.6!/H%G''$C?;7@6$.EC?;27(*
@r7175
AATCGCTTGGTGTACCTCATCTACTGCGAAGACTTGACCTTTCT
+
2<;;46F2.3&G/@7DA<8+%5()>D1'2"/#56D(>?ABFF;E
@r7176
GAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATNCAGATGCGTCAGCGTGATGGTGCTGCGCTCGATGCAAAATACACGAAGG
+
@B4-"@9"+>F1>H.6$F;3AD=0969638E0A/'"C%8:E<5&$0.<(C$6,.D><)-.2:+F,(-6%8C272%"=?=89E='04"
@r7177
TTTCTACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGA
+
F=$/5A?&$056.620H-4*>:)62=>=5#@)?10>GDG%,2.
@r7178
CAACCNGATCGNCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCT
+
)<8F749B*@E*AD@6@=DA?%(<+;:='*)-E!/%/6A.693E!G.3%<&G+#
@r7179
ATATCNATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAG
+
.G#+2D7AF!E"-"C9':?13*?(AA5A5;>081C&0E9@#2H7E.+)C056;48258/(HHB47D%E%3@EB@4$)EA?1B;)&AB@?1'D#-$/!?@%#E>&4:=D4G=/#A".)7%B$G
@r7180
GATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGA
+
&1)5>E$F<H+D=4/(-<D8-<4-B':/$.H<?>.EE8@6+!840.4"?:2GEA7BH&,<&=$?/@7CFC+92B2;5=4C/B-*F>1->3"C@E&C@27A1!46@"*DC@@-)6&%!G@2F'%!F1=</=G$92
@r7181
ATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGNATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTNGTGGTAGTGAGATGAAAAGAGGCG
+
,H5;HHH!#("$E??/35%B=E.=$$3-A03#+92)C;,C9.1G>CD;?.&!CEB6*C+(?)/G7<&D>6B*C1..,)#+,.C)(C4?!:@=+<!0%;0&:@8C*9864@9H,2=6+"0,&54%2A07
@r7182
GNACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTNTACATAT
+
()+'"*%(&(''"(+)+)&)%+#*#(#*"$!!*"&('!'")+*#$&&))'*((*+$*+*$*+&+)!&)%%*%'#"+#*
@r7183
TCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTG
+
,54910E<*@=F)9>"4;/*3!)F'')15.!:26$E+-<&
@r7184
TGGACAGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGC
+
!'#&&""$#+!$""+$*'&&'*"%$!!(!'"*+&''%&("&("'
@r7185
GCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCC
+
'>G+2!959)#0.+9G/1D6)1FE>-+8#&E7#!.38=FG)2<>@6E'-+/G;)7,=(36(%1)#7097&6HD4A-:9@61$F"?7#<"HD""115H,'5=)3>5"3!A*6-)=%24+1*?$E?
@r7186
AATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCCTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGG
+
=1.&"5?;D5.$5&9'G73+C2D<"?0H%*>;9!6''2&D78@CDC>(!7%.H1<H"7#(6"';<9D+?H@4)>0E8<5#:@)-64!A,6B)#9DH$10+0'<9=*7A%,!6(..+5,F3'7F*%+=(#"8&8:<!,14GB3&>GGC:*E2-%8,
@r7187
AGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGG
+
.+B*,):@#9!07>5;>--G$*1>;DA'7>;$:+?(?)3%9!#+2(2@/>11,9'#!7CF;9!!02<0%@A&9A.)78H%+4A>5H"'1.$0,#5-G%2F/5C!-3#%:!09E>0D15/$1%)*7<D9/?.7>3.86-7!+(D5<<42?*,@%-)62=>@,0:
@r7188
GNNCCNCNNCNNNATNTGTNANTNCNNTNNNGGNCNNNNNAACTANNNNGNNACNANANNCNCNGGGANNNNNNTTNTTNTNNATNN
+
!##!#!#!!$#!"##!$""#$!"!!#!$##$!$"##!!"$"#$$#!!#""!!!#"$##$"$!"""!#"!!!$!#"###$!$!!$"""
@r7189
GATCAACCACGGACCATAAAAATNTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCA
+
)$())+$#+$#"%*!'++"'"*)%#'+$(+$)(&#"+%$'&)((!)&&+$'#*%%$%##)!!'!!)!)!%$#
@r7190
GTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAA
+
$A0G;=C932)?%*A9(-,5!:>8109-9>,$4)#5BB@$A>,#EF9A(A!-(.%-B?!8,?9-GA;
@r7191
NACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAANAACTGAACA
+
!D1@='-2F*>531H;G6@(('"-0#'62,&:'F%1'-@58-3%C70A>4G!>9-@8%@&1G,,7F''H>)C,9=!G(;,*4$E7(3A@>=%H
@r7192
TGAGGTTATCCGTTCCCGTGGCGGCTCCAACTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATTAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCG
+
.<%63&#C3$/>;<5?-D,+@5'E*";.(F4A,';F+-9005F!46&#82F52,7+3<F7?'!$(@!7F),@@?GH";++A6&41':#9/"9;+<+7&.D%HC
@r7193
TTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCA
+
#"+(!*&)"%)'"%&##+*$"*()*(%)&+$&*'%%''+$'!#+%'&+"$)*$+'*!%$!!&*"!#!!%""*+)"%!&)&"&"'%%*$'!'%$"&)$'&%%(('#!'&!))&+"+"*&!'!(#&&(!"!#)*"#
@r7194
TGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCT
+
!1,F@D/9F68CB*.F$'"3/+$)G;:HB/!B<:./>E6+</<,>?)(E:5/,2G").3>3>)
@r7195
CGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCAC
+
2+!(G4BF<%-8)9*#06%$G('?@CB'10=52;C')E5=6C*2G(EE',E;!0&@6.10;977,6:/(?'$5"BAGG4:01H-:"?---1%-.8EA1GG
@r7196
NATGAGGCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTC
+
%E,*H3*!@*7=A>%36="(0@03&6&B:40A0=5;16*'GB8C?)B1DE9G7*'!B*38*8>G.6F9=/:$7<+?61$&EE93/+4>5
@r7197
TCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCNGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGANTGCTTTTG
+
)22D&>!&FA'AH(4*6F2+%11'5/-43#2F@->C*!:"?6<$2:*-,50"?'9?(A9<#C'!""95,;;.%;C79:(&)8
@r7198
CCTGTCGGNTCACCGGAAAGGACCGGTAAAGTGATNATGATTATCANCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCA
+
'0=5&#5A)=;&EF0(2/16>+;4D5H!<,109+$:6=9F'3(/B9>$B6F*62$:188=<"BHE13=.A=H(#F2B!>%<%&>#+/AB<@*@$;?
@r7199
TATNAGCAGAGTAACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCT
+
')%%(")'+#)")%&$(%($!)"*#&')*!!)"*&#+##"%+(!%!&&%('&%
@r7200
CGNCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGG
+
!&$+*!%+)#"%!)'**)$$'"!*(&%&%&%$+&#!!$'"%&+#($$&#*&"$&'%)''
@r7201
TGTATTGGTTTATTGGAGTAGATGCTTGCGTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTANTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCNTGAT
+
?%>C2C7/8G<E73F5"(3"?(ED324>+=A8",C?&7H<!/#G)1)3(09;=D879;6&$CG*-&3-(FB.(.D9ADA6G@96%!=?%*A%<FC(@'3/35#+B?-46#%'*),;;(+*>!3&'8B>48
@r7202
TGGTGTAATTCCNTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTNAGTGAAGAACGCGCCG
+
H"942+!,;!DH75DAD/!2/<H>$5GF5+A(76*!D(8$(7B10>+A@H,H;$(4)4:..>2:)!&%CAE';<%<47BFD71
@r7203
CAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACA
+
&<:;5=!0-AG,/>(7D%0B@541$&*+(<0;#-%?.=!CEG!#!:)%*3E-5?5(!E<G-!&7/;3);@2!(.)F(4C/C1FG"8'8*=#E;452%(#,C%5F<1*?A$F6<'57@:6
@r7204
CCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCAC
+
4D?/A=,-=5:8.'43EG?&<B>)%+HC96F8+*5<E.@E8C'05<>'!@7+:28&9?')(45&)/2+<EF2#4(0@*%D>B'8,@*->B#0";AE,4H;=@/1(;"%*3C43C;C+!CE&$>,(#D$%B$.D<-&89)7A+<&71B&EF/>C07?0!F(5.2+1F)'!"%""@3E@?)8#926%23B(H2+*B>AH'&7F*H$D31?,/<5-E'9.1,<C"'=G#>(D&@G@#B29<:#@;G%,G!2">=*%A9C-"3@!:4>&=5<?3H74.BA2842#907BH+'&7)-GF@?0,B&0A/H$@D&<@*A5H,E4>-3GD3?#$"/>#?1)%6E42'%>%;@#$=+:+)>;2%(2@0@2;<%$+&4>B+*/%%6!5-H!.>>)D&/!&FE+DF1/<'-7E7&E75<:B;=<)B)9';!7H/:22G29%E"(C;
@r7205
TTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAANATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAANCTCTGTCNCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCT
+
:+36/?7F+5A40>D/@$#&,#88&6A3*4H1;@"FGH/@'!!5,H/,(,%+AG98<A(1*'-+A>ADE?(#:12&52!G'"A2?2AE-1>37?)7(E0"A3FB'!<&.1?#F:*3@F,$:6-3?E>!70$7"FD/,5&A!&>")9%=241(A)*(.-8/2/3;<#=!C0:E=;@G$79D=(9.3;,7B>B(=@G/?4A!@C>G,;>H1!?4:838.)!(4#.A#)")6<*BA/.)?&!&9E4'D01.0+E'<2!,H)+E&,:?E:82CE;4?>$8,9*45@,/A:>=1*+H49%=5
@r7206
CGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAAC
+
7&H1:AC+%>&,'"FC-G%!&4;7G2E1+?D4)=5(%D6')'7?=-1A."$3%$70E-
@r7207
ACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACC
+
7$:$4),431"E8:8A0*3C-),)9#1C"&(+E1D#3"*$F"=A$:FA$6FD6%.3@A/
@r7208
NNGNAATCCTNACNGNGNAGNNNNNNNANANAAGNAANGCNNNNNNNNACNNNCGNANGNNAGTANNTCACCNCAACNNGNGCAANCNGCCNNGNNCGNCGNNNCNCANATNNGNNCTGACNCNNACANACNGATNNAANTNNTCNNNNGCNTATNCNANCNNCGNNTACNCCTCNNNAGNATGTNNTGNGTCTGCTTNNGTANNNNCNCNNGNCNTNNTGANNNCNACGNCNC
+
!"#!$$#"!"!!"#!"$!"!"$"$!"!##""#!$##$""!"$"!##!##$"$"##"$##"!$!$!"#"##$"##"$#!"##$#$#$!"#!$!"!"$"#""$!#""$"#"#$"!$#"#!$$#"$###$##$"#!"#""$"!$#!!#!!!#!!"!##!$#!!#"#!!"!"####$"!#$!!$"!!#!!$#$!$!"$"$#$!#$"$!!""$!$!"#!#$#$##"$$##!$""$!"##
@r7209
GCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCNCCAGATAGTGGTGCTTCCGCTGACGTTTCGCNGAAGTAAGCGTACTGTCAGCGGCAGAACANCGTATTCG
+
+9,F$<A3G/0%(@?8=>/,:E(85=8"=;80$:#3#F&62H"EH'.B<&:28:&)D2+%AFE$3'%1B(2(G3@!,>(2%0/G*(<246A4%40!4%#1+9<=,/<G:DG1/6H.5G4&-:<G1'B849<2#7
@r7210
TCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTNATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTT
+
$;<F9-B/@.<57753%,",-GC"$B4E>>+7++.7%EE0@(=6:?0)85&A0)0$6*2A@#H:0H;3GG5)D)/8B613(&2;3;'H#,7=8!19H3+D%B??#3)H1,0F7>C>3@!/*2B;#FB%GG';7*85*'72&DA-,581>:F>!6.8@02!D(FE5.B!0'%5*B*(B/$,C1//-)2&,7+&E&$,754D@!F9$7GG*,5@+
@r7211
GTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGC
+
(+:B=C5.74F-.&:.B'.9*F648:;>-?A1;=(8E&-)97&/$-6>@)F(88=.
@r7212
NACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGT
+
2:%G-6,F?3%((4+)(<'@G'6)GD9><&.?%1-==(7+
@r7213
ACACAANNGGAAATCTCGTTCCGTATCGCGTCGAACNGATTAGCCGCATCGGGCAGGAAGCAATAGACGAAATTGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGANTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAA
+
)(%!('#!)+'"))'**+%"$"$*)*%($+)+#'+!#)%+#')%&*$#(#(*##**&!%)**%(#%#&)'!)*%"#+#+&%#($*(##!+'!)('(&+!)()+#%#!""%&)&#$&$+'(#''"))&%'!(#%!+%(!!")#(!()%"+*+&"*#)&($'$'
@r7214
NGCCTCGGTGTTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCA
+
"$>7-7!*8H$<*:EC)$12'<;+(/B8,1!H6?)1('E6?9?>2DCG3AGC,/?9/-1:6'H*.+G&4'C<H-H54
@r7215
CTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACNA
+
>75D6=C+!@%BA*36(7.@)(#,D(4%C+GF@>8/GG:1%=&3<&
@r7216
TCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCANAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGC
+
";!&%:0)>:"!8F.?BG1B:,'A>7H0G/*%6,5E)@H+.2CHH>1""#84=2E<D0,&4?)#&0-)&;4=+7.'*6C+,H?913@G>1!$H6=95!<B>-2*?$AAG26<9:F0A<BF?>5)6C=126:5
@r7217
AGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACC
+
'H;%F9E.555883G1;FAH7#!-!$1@BCA+#-73=9:2+H.:-$#=3(%<1?80
@r7218
GTGACCAGTTCAGACGTATCCAGAATCACNGTNTCCGGCTGC
+
#@$/>%.=*A<DH,;564H+:(G*'/;14CD46C,!F@:??+
@r7219
GCTCATNANAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCNTTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGTATACTGACCCGC
+
(*&$'*$'!+)'"'!%"&"('&'%%*+!*&($(!%()%*+")$++!'$+)&*%$#*##*'&*&(#!+$&"!()$+&(+)%*'!++"*$)("&%*&)#(#&!+'++'$$($)%*#'*(++'+!"'&+"&+$"%#%&)+#&+)%&$*"$*%'*$#%"%+*)"%&!!")$$+$($"#+&&#!%)
@r7220
GACTATCAGGAAATTTTTGCCCAGCANGTCCGTGAAACGATGGANCGCCGTGCA
+
2B(+3,/>GA5+3$0"+<21(#82E557H*)$76A2%3H#8+3!0AB$50**?3
@r7221
CAAANATCAAAAAATACATCCTTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAG
+
'/?F-FE=9@=.+AB0*2(9&:/";C9#E860B%<'=%(+!H&*;*:?:F*.-5(@(&&,E>/CG30+=:3$E7,<.EE61)?,+4&=2B;#*G=
@r7222
NAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTNTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATTGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGNGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATAT
+
#+%$"'$+("$%%*('%'+$&%&(#%$$!+($''+#&&(%&)+*&%"#'!#!(+##$)*$')#+#*$"!$$*&(+++*!!%$&)(+%"+"&*$''"&$)($%$+&%*&)#+#)($((%'+!)+(&!++#$%+!""#)"%%#%!+%"+&+""$(*"$'(&)"($%&)&&#+)%(%+!+$*#"!+&"!*%!'""(#+##)$&%%+#(!#(#+($&&%'&))&&#('
@r7223
TCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGNATAGCTCTCACGGAAAAAGAGACGCAGAANCAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGC
+
B!3>B4:44G36'G3@*42!6'3,8:6B#$F6C'B@1)6A+$/H+",:$A6&5,482/.:':>>97BH;8(.8.=F:'C->&)*GB6'.GD<1:$<..2&%(G91?"C+'!9,B5)#A>/(78&,(<?-B-(="=8D(',6.0E115C>.#G;<4"A%#!-D:D:94CD3*A(@/F1&GA9/6?#'5B69:%:85$G()+5-DH93AH;"C3EH#.'HCC>?;%?D"3./&1H$39@)G.$'C36G!*>$#5;&<0(9;C':+30!:B11"B%6%(!C+:&,.8(8#(*.2$H13AC:GGA8);D"4BD:!%:'2-7GE;#<400D?"91>AG=)47&#4>3G!G@@44H
@r7224
CACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTT
+
C76$0="==:..A'F-A#$%.$%3!B+6>F*EE+.)>?$H4A+:(43%7;
@r7225
CTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCG
+
H/#%8BA8,;7:-6=G:;@#8CC*4%;C@F9B7@F.&>);".G/0$1!<=E>5D#4A*#8$+(@%A>F40@+.E!)9"3
@r7226
CTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTG
+
@9()>B2%958,7G(/72#.'<13&<H@5:C&G9;*8*6$?CB2";B.B=-'."4&F7DC78="DC)*/@H=EC(A$/+G!
@r7227
GGTCGCCCCGCTGTTTTNGATGAGGCGGATTTTCCGGCAGTTG
+
G4#,C%+@4495/8(8F-*BBC*A(?=2(&0%.6+-8!=>;;E
@r7228
TTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCT
+
))/"5<:E=HE!FBH5>-9H#AG9'"/'"*'%-@G&-<+C
@r7229
GCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTNGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAAT
+
CB$$C,7H5G-B-**!HGD4#*$+?A8&7H29!2G098=3<.$:="*@%3%#>@7?F/92->.%12F"1;).D<3H11?B<CHF(EF65)/A>'@(3%A&85"59<.9"A%H$9@7B.<14!;=F'#CA5:4&8&#6B%:03-8(.;?9',B+F*2(CG71C=3B<=(
@r7230
GAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATNGTTTTTTAGT
+
4'=AH;8A1!#2),9'1>8H859'=%942BC@A>B03&4,#&1$#D$3#,;E-F22!(0;@E;&2&9?/G69?H1->G2$/*@4*@-%*@4/#>/%+/*32$&3BGD38,8
@r7231
TACCGCAGAATACAGCCATACCGAANCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACNTCAGAACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGC
+
F!E4A;"180,AE'8+3:!*;,<9C9%9659B3/13:>4>GEE6+1(>38<GEHF'F;2;3G&'F$74";G/6(A?DB)06(G/%;G-<#GF)2$.1/#1#$<?E/:.-C84,7?05.!70-2:@+)1@H)
@r7232
TAACCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATC
+
"HC.<;8:G'=.7"&!0D@37DF22>)3%C5*!2=@F(>8$1BG?0-;.>
@r7233
CTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATT
+
G#'&36A2)73@?#<#-":&&<A<+2.><+."G*(3;.H:5560,2+/""/5-0B@2:D8/A1A0=/302:C%:)#<CE<1/H--#47
@r7234
CCCTCAAGCNTATTAACCAACAGCTCAGGGATTAATAAAAGATGGCAGACATCATTGATTC
+
5H(@8/9C/7:0,3$%+,1-B63!F7?=A332*"#E%$#E?";6(F"6,0-0,%8&=<!7<
@r7235
ANATCAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCNGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGANGTTCATTACTGNACACTCGTCCGAGAATAAC
+
%#*&"'+'+(+*%)%))&+)(#%$(%*&')()%"+)'*"!#++$$#))'))*"')&)'!*(('#"%##&"&*!$#!*"")$(+#+&#&")*$$)")&#(()#)"%&)!$*""+)+"!#''($(&"'##(#)'((%(+*()&#%&"())&%!%$$'&!'(&%"&(!+)#+%!'$)#*$$*)"''+$
@r7236
TCAGGACTACACCTGCCACACACCACTAAAGCTAACTGACAGGAGAA
+
+")##'+)!%)')#+$%)&'&)(!&#!&*#')"&&)(&##%&*&)&+
@r7237
GCTAAAGCACTGNCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGNCGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCANCGGCCTTGAACTG
+
>/!C-9,D057156+39:$A5B6:;:1<F42D-@B.>02'%6/#=*+*0FA;7E-C1"C#$*?22.!?@,--7<%6)C-*4,(4!0:=;<E/&&E6!/AH6@C374%0*3+FB.G%<?BE3A8$H#;!:=,9$5#C+(01D4$(A@D>.'+DE9<!,)DDC"%56-/*
@r7238
CAAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTANACTNCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGNCACCTTCTGCGCAAACATCTGGCGGGTTGC
+
")+"!&&!*)$"'!(*&('%&'&"*$$&!(+"&#&+"%(#")#&'$"$*+!"+%(#%!)(!%")&#%*#!!&%#&%#%$*%)))!+"!&*!*'*"(#('&)!*#&(!+**$)"$%&((&%#(#%())('&*)++#$#&%#"*'!!"!+(%'*"!$)"#*!('&$(&$&$)($
@r7239
NGANGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCA
+
"&'%+*%**")!%"!%#&&$!)$'+'+$)+!#!%'!$!$')("(**!#)(++#*#(+'))'&%&"'$+*!)")*%(!'#(%(%()!(
@r7240
NATCCGGATATGCATCCGCTGAATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGNATGTGTCCGCTTTGGCCCGGAC
+
"25!'?2>A$%B&=<90/1<D8.H+EH%6%<H:35=E2"F7"?!*F".,":.E%=.!$D6(5=;80,CC0B'<G)7:3676(,837(',840'!4.D%H9=3"1!;'B=G8:*)>#<F8<$/"0&)
@r7241
NTGTTGCGCTNTAATTCTTCTATTGATGCTGAATCANTGATGNCTGCCATCTTTCA
+
"?@=!0.)@3(?'B16C69@C<0:+0>/G+&).=<?!E=&.G:94'(@C**0>(C&
@r7242
TTCTCAGTAAAAACCATTCCAGACATGCTCGTTGANGCATACGGAAATCAGACAGAAGTAGCACGNAGACTGAAATTTAGTCGCGGTACGGTCAGAAAA
+
@76.1,D#<9/07:0@9E;.(8*5)F:<D2)3*-AF&3G#*D@/83?7"FCH2"?'%3-14A%!48/",/4>G?*($#H6'AA.">&D9#9,/8$9.9'
@r7243
TTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACC
+
(!+(!!+&+"(&+($+!"&)()**)')%$'%$!+$(+#'+"($(!%"'#(&*&$(++(*&%(%*($*!%&!&!#"")(&*)"$(!!(!"++)$$#%"++)"'%%'"&"%&#&
@r7244
TGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGA
+
<#814)862/';C-E6/<%G&',-##;,//!"=$/.?DEA.)&:=45?D>815;
@r7245
TTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCANTTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGAT
+
C7.$9+(B%;?+F&8"5$G3G28%5(.:H;2:A8E>'#).<9'GG11#):6(AG+)"CE?=-9DF2-5(%E%>"9;$/,'B*27CD)%-'/B@12"/,1F%!0B)8'!:=4<5=;18>@2!)$4C1GB!
@r7246
TATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCC
+
<B628/70!$7.0%>+',#C!EE)/3>%%%7=434!0>@F#7>':3!5@!D-G#>"(#C4:.E?("A%:D8%G9CF4A$@:&#+6H%99,#7B@7DG"<6+8*E08BB;@
@r7247
TAATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAG
+
")>772C(,C+3+.;$(7#B37-1@.:0EF1%!"/>8*7:C!/4'*9#./$<16)9.1
@r7248
AGNNACAATCCAATGGGTGACGATGTGATTTCGCCAACAT
+
%""$$&$($'+(!"()#+&!"+*"(')+'##"+!"'')+*
@r7249
GATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGC
+
A7H>?";F<6)'CC'<@9:#8-$?87">3.F=ADH88?=(7)%(")3!)(733#F!E;0"#'6$-EH+1(42(&)H?4A:8;9'A>+;7;F6&;@%$+6'1G'-9:8>F:-")!:;@62AAE#0@;:(2#4&=9E3/DG<%$-
@r7250
CGNACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGATACCATCCATTGGAGGCCATCCTNCCTGACCATTTCCATC
+
,5+/!CC7$H0F+68#3"8A$9.$-$GD5#+84FF26F00>G>*BGG(37#!F6H%D%-.(>-F)E(5(1@GB$=3*#.5:B2>-/$>=H8>7'7'B+5%;>26@H$($D;,*,H?E#(,80
@r7251
GTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTNGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTG
+
90.(G=69G.'46D3DG#3G(6:B".H01::-?!1#;+.(*9$1*:C3D6-)(+H!@'H<0:#AD(=>+)$@1)):$9:E7:$/-:&1<C*592E>?)(C5B!/E:B1-@=(,D27A?#41,B0@D0G6)BC0;8,9"$'6&&7@%,0A'),D3#157G+F#1)06,3+D5931#2E&/59+22/9$/7F'F:35,@3?(-3D$*.*)@"%)GG6C):+;9&C'8H:C%("!;<+$2,
@r7252
CCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCTTAGGTAATGANATAAGTCAGATCGGCT
+
:H.,3!32)'+(D!"-'!*1#.EH!&/%=94"!.@-9-!,D.#>+A@9;E4B<95B-!,;;3-G);%H@$!2
@r7253
GTGAGTTGCTNATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTNGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTNATCTTTGNTCACCAGTTCGA
+
0%747AA'9%5D))5@:,<D=%!"$#,"2BC"#1B!)4;2+3#$D7)@>/-9"E#B0.HG#0@<,%*<'B4*-"$)<0!D+/62+<;+0B8'%1?H%39=<?73,-0@2A93@$5)%H:GC&F!>D6;;
@r7254
AACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTNGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTT
+
7=3$=?2"-7'17?+:F-9-%EF-D-@.02C4<)0D=5#?B(8!=+A'3%@?H.'!0-#&=*$?0*&4/H:F?+F4C7)=;%DC1'G)E/H80?37<
@r7255
CCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAG
+
89DF5>).<54>%$0?D+A6.@#9,7:6>/11>$230%54-%,-:#)-4";"-E952;/$5'*E>?4.&G'B'@)%<,?!
@r7256
GTCGCGCAGAGAAACAGGCTCAAGGGAAAGCAGCAAATCC
+
C1,.21"+HE806?/B!&'G5C*?3(.@G'27+;*5*FC4
@r7257
AAATATTCATTGTTTTCTGGGTTGGTGATACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAAC
+
C(2E';F$+2$9??"#!&1,E0-F<E9$7F#?)>>3G;<%*&E1%9,-&BC,7.60(?A-7C-%H(95!-:6'>4>3$@D+%H=<D/;=)F&BE'0!7!:F51A5@-+01662=0$
@r7258
ATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGC
+
DA?C29>82HH!>9)/;"+%61<,&"8.-'%4":DF:(C0-EH$G&;/,<=&:?<$2$E3E#4'(H6<4.,#7,9.!)"0
@r7259
TNACATGNAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAGATATTCGATCAAGTGCGAAAAGATTTATGTGAA
+
"%+$%)#*"$'#"#'$'("%$'%+"!+!'&*$%*#*!%++)")!!)%(&(+((!'**!&#*'(+$+!*$"*%("%!$$!$
@r7260
CGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCCTCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCA
+
>&$1>'F&AC2:@A(F$B:$"',9G?=::D"=<<7;=61,?=H4A06+84=!%-4B,&@;=B,9)!G1"#<F!#76-@5;77D!H#'4'1(52"$D.!7)1-H>/73#GC,3?7?#"C-873>?@$D$G3.2.++D'?"+.E%/"628<*!7;%)>E)5F2-22+%><5!C:C8:.@G&5HBF=<+.79H)'*1A870,A2DC)%4(/>02.
@r7261
AGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTC
+
+"(%&+*$!)%'+%)'$'#"***"(")#(%"!&)#'!#"#)%&!&$'
@r7262
CCNGCNGCNGNGNCNGNNTATTATCNGGATGCGAAGCATGCCNNNGGACAGCACCACAGACCAGCTGCAGAA
+
%'$)&'&$$'#)"$$*(&$*"$(*%"&*"&)#&#!"#)%)#)%'!+(!%!!+')#%&(!%#$((*&&)'$#!
@r7263
CGCCATACTGTTCCTTCAGGCGCTGGTCCGTGGCTTCCCGT
+
,'@H0)"?,E6B)9D:>-2*25"5/::G6B<C3,28;+<<&
@r7264
CNAGNGGNTGAGACNANTCNGGCNACNTNTNNNGNNGATGCNNNGNTCTGTCATCTNGCTTNANAATCNGTCNGAGTNTNCGNGGNGANNANCGANNNANTANCNACCNCCTCNACAGCANTANGNCCCANGTNANNTNNCATNNNANNCTNGTNNNNAAATCTN
+
!"#$"!#!##"$#!!##"$"$$!#!"$##!$""!!!""#$"$"$""$$#####!#!"$#$$###!""#!"#!#""!#"!"$$#$#!#"$""""#$"""!!$!!"!"$$!!#$$#"#"#!$!"$#$!$!$!#$#!"!$#"$##"#!!$!!"$"!$#!#$$"#$"!$
@r7265
AATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTC
+
CCB%H"-D<3C9.4A*%?-$"D@G7D%64/6F?:BA#A1B5+0:HF,G
@r7266
CAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCNTAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCNGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCNTTATAAACCCACANGGTGGTCCCGGCACCTTTCACCGNCATTGTAGGATTTGGNACAGGCATAGCGTCCTCACATTTCTTANGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCG
+
0>0$@%D8,?A4;$.*)D6?D9/#=+-.219)/5<3@5&3&()*B'H,G#A4)$4-?5/:/,+($BE?E)B99G1C-C4>1B!?,@:.60C(/,2'),20/2#%6,?1->G251:":4*)9G#>:)):@4/-C!@*7#0'B>95A1>C3HC2*H'0''@9-568>D"8.+=*'C).:*C'+3G7#>!G=,$,95G3G((0748EA!78)"C1B&?,54B49"@FA%C78A;;$8A+;G>5#=1#F)#;$-=!@B,,A$FE)7A/&7-6::%'.1$HH'F9%*<A:-@$$;$CC$C4,
@r7267
AGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGC
+
)+*(*#(%#'%+#!$%&!')!&#+$!*%)((!)#!('$$*(+
@r7268
TCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTNGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACA
+
4?*!33-63+(=/#%5G&"0F95+.%&%H?-?*-;H?&D1.?,"G'>:5&/+=1B;=02G((F$2(*%;4;%F1CD9E/%*%0#2"D<)1BC<:%%%A>3310&&G5E?32?6*4=#+49+E@>92">D=,-G5F1(8$=6;,-0B)%$B+$,!,,'(-D8B>):?1"06*67)>);91-%H8.?,3<")
@r7269
NGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACNGGCAGTTTCATCCGCGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATG
+
"!2')>3+C5F"D-</:E1%H):42;E2+2-88$./E4H:B@-$G*,H.&C0&F28HFE"7;/(?/4?(,0B(H=%8$!?-3)'G5:5G>$A.3ED-)FB;:8B,#@*G?6*;A8/*B@2.%=G1,-1>;$.5"85:8?9,"C;';,87/(F-1,@<7%-,$H138.F()@'GA,,;>)37@21
@r7270
AGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATA
+
9(0<25C6$A7%$6+)?<*45(+=":;0DF&*C8=)8$E<G2;FE*5'%(0&'/!,75<?!=HBC"#><!?0&3-&8+4(-
@r7271
TGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGC
+
1!B6<FA7":G)>F"!3B?;49:#9*?-$@2-<=33H@--3<C*%>HB&/;,3-5!'5!FC+BDE$31!#1-F5(/8)/%(#F=49/+56-<B(6C6'8>$&2@A=?BAG:3G$E
@r7272
GGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCTCGAAGACGATGGAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAAT
+
'=A="40)?+"=,8-$#31&=%'4?$&.(%<4<'480+C)2)9)=6F*"4D'6D<+F&,(7,93%G6;;%C8BGC+F:F0D?%<5!"D,38.,*9;03AH>;&"*AE'*3;EE701;!D-.,!"5=$
@r7273
CCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCNGGCGA
+
!+"+&%$%%###$#(%+*%&((')#("$+('$+#'*)'"%!!+
@r7274
CTGCCGCCGGTTCCCGTAAATCCTACGGTTGCAAAATGGAATTTCGCCGGAGCGGCCTGA
+
"9A2$?A$!?A9FDAF#6,.=*(!7?"G4""!++F9-DFH2<?5:$968+G:A/@4()@B
@r7275
NCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCNGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGC
+
$9H??4D)C8&,8%C-HE((A1%62=?:7D--.E-$1,61F#7>7#"5#;37<<>B*:?"5*CGE/$H!2%"D==2&5@-38$DDA3GB7BD#H$"$'F"@'"E=%&-'?*A3!&;?>'DD/*=>)"8191%7+-60$A">!81)B1H<CGC?C-H<.H85,>?#+5011;96;;&-/7,?3/FH,8?3*'*+E
@r7276
ATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGNTTTTGCCCTTAATGGTGATGTCTTTTTCC
+
4"?1&"$=/-"<26G?FF+BDAH@*F)1-1(E77DD)H?H'52%(#&!H364%C;?=:&#EE0F!+0$%9:C(::.,&#6;8+;3&G%.<%CFG#D',/EEGE.F<4!9HA5@6AC!A.H;#0C4;F-@1?B13'"!F0%E8F&A+$.*$%1.(-9=EB)&A8.A5G?
@r7277
TGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAA
+
=*0+36B==:(*')E'#$CC=0H/3./,B02:'B>+9F8)(#@:H&+!)=!G,'
@r7278
TNTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGNATTGCTGGTTTCTTTCCCGTTCATCC
+
"#E?.+=8&3.=781CBB6>>6:$+3"-D,).=,=&?H2#0#+1#'BE@#62/'%39H#A'#<G9*.&<
@r7279
TNCCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGNGATNCCGTCCAGCGACATTCTTCCTCGGTACATTATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCNCATGGGATCCCGTGATGACCTCATTAAAAACACGCTGTAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTNTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCTGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCC
+
D1#:=@F%2<0EAGDA51(#9@7";CH+$.1/<B>5G,F<C'="6D%8/+H3-6:0':,B9(7.H.<G)B#;G>/G",*3%C,7.">46E9&-43D.8EA82E8>):1D9C>/1E*62*.0$CC'3*$=;=;6B76!BE-?5&=:@,4)G4/C=2;!)(%F95D)&1E<&+$=%(=/@(*4EC).?%)-)H!D0/*.4/$4356*<=!$>16%652D-6D#.*"+5'B6#62C):4<*G,.05=-?E=);334*2(,$>:-E5!2@5@:<;>B'2#$@..*G/4;./(B8622'-84'%$>%)B)>(47:HD)&G@H0!"8##*A-:1(%A$(-#G#B66H5E*43"3=1=>8$&(#3H2<227E6,*@3:94!GD>.*##&"=>GDH1G
@r7280
CCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTNTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATNCAANAACACCAAGNAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTG
+
,3<-"D*AH%6@32E'"05A+)@!'?&22C*"+52-0,2G4.5:=6!9,0)E1%7.,(2"/"5B6:9,:1-;FE$?/-(AG&CDD%2FG0E*E;1,+*(!()4*,.(@;3G(G+4,/123"A64,/,+//H#0E5@4'4F>:$:96:9+D$/='1%BC.H/:-2#(&.?%C4E$G6@2(E)+E2+3H"F,DE+$#A+,62"%1:H3CG1E"(3-*-":%,4$<?7>(A*>8!;7="),0625&7.'##*#:1E8;F.113@E75,2@E-2<6%9,(82F?F"A>B(?EA/*122-
@r7281
AGCCGCGACGAACTGGTATCCCAGGTGGCCTNAACNAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAA
+
-5$FG81F::=#-9A4);%5-*'43)5@;;F?*H,"#="5$,7B5/?:C5)%./3B-4*HHE5H(!-!1;$<2/4"1=@G)%5/F'6B%8:F
@r7282
AGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGA
+
9#6/$+.*+6+H*+E<+;>!A1"H6G-A5$A>'F:E$5.>B"=%))/#4:39H.'82!2&019F6"HF(:8(B.267/!09C!$E@E$4E:%.9&B!!D6+<<=&)60=@"+:..?04@FF(.%;!6G?5:,A;91&>>H:8?H='97D34-C
@r7283
TAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGATTATCTTTCTGTTTCTGCTCCTCTC
+
;A136,2%@-!?8G!>)".C'2-0)34A*F,)&F$?*=095*'/E2+2BCG+E:710"04'#&B-%"5E7,8
@r7284
CANTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATT
+
*""11-:+,2)ED82,9$/=AE%A7$EG3<G8!$+<:,'9,5:B7;'&';;79B<:+A9FH(7
@r7285
TTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCAC
+
5"%@.&*49F$85"6%:<>9$5"%H7.5E,E'#3CE2(04F7%050..,/+&4;-8788(5>&&#EE-!3-B88**21)
@r7286
TGTCTTCTTGNGCGGNTNTNCTNNCANCANNCCTGTCGCACTCCAGAGAA
+
'$#)(#*&($$%##%%*$'#)$$$#*"%$"$&+"!)(&(*(++#$*!%("
@r7287
GCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAG
+
<?,C;076:3<61F&HA,/@/2:>C)C@>F4G*CD5<";!,CF20#(*@%,0<H:E=E).DCAH-(3408.7&282495G-+,.=&+A0&>(63'?2AE7F;)(&$E8$:F0F*A*%&>491-D*$<DH/5-76,)@%0'4>BD.HE-8'17'=;&244H*?,GC+*.3A=21
@r7288
AATGTTCCGGATCCGGGAGCCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTG
+
(!+(!)$$*%'+&!!!$((()*$+#"+(+(!#%(*&')*+()(*%"&))!$$#*$'"*#
@r7289
TGCCGCCACCTTTNAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCCAAAGGACAACCCGNGCATTAC
+
*DF?--D=<?6F@F4!3@?<@41.48?'F&$(:34+<7@?7H0,/0!<(,E;9%D'/!,,<"%?()%D;E28$%,
@r7290
AGTCAACTCCCTGAAATGTTTTTTTCATTAGGTGAAAGCATTGACT
+
)6D-$>/-H-#G<HAF7<+2.C:6D</>83#C=.#43)=<AG'B1"
@r7291
CGNNGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTC
+
*#(%+$)+'#!+!("$'$(%&)'($'%&)*$'*+(#"+&""$!!!%(*('"!+!(%!&
@r7292
GCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCG
+
H(/?@BG"(A@>H?G+:*H44+D"CHFB>3*1>>1/!)%9F&;/3$@$8E#&
@r7293
GGCAACCGGCATGNCCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCANAGCACCACGCTGACCGTGGCCTTCCAGNCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGGCTGCGGATAAAACAAAAGCCACCGTGT
+
+H&H3+<3<#:"('#H,&*4<#>832;D>:G$A=E'0G@2A#7*86F,(<-@!*$,79#=2D2.<EG9!@5$("3@!:10823(#=;F/%&7*+38+EHB?046,*%9GGG/1;,8.-2A,!&5:8*7/&,:,+.9BAH;'5'
@r7294
TGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCCCCCTCCGTCGCTGGCACCACGTCAGTAACGTCNGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTC
+
232?2G07;E8162A@.H*/(H(+8D3,9&>G<F?EBH:0!%9486B=7@"7)2;%$A23564#17/H:19C,B-4?))/%!0''ADE41"E-7E7=C19=C24>(.,)(44C@A&?<)61$(@?/2)9*:&A"9,#>>9F$C$#'(>>6/=(.'3E*@'$.9*:C<#4FF#"8&A('?@H)7-5?<&6+?*";2*##+.D$0;;
@r7295
GTCACTGCATAAACCATCGGGAGAGCAGGCGGTCCGCATANTTTCGTCGCGATAGATGANCGGGGATTCAGTAACATTCACGCCGGAAGTGAAT
+
6$$,&9G3!C<$+.=$4#'4!G29AF:4@EG4")7C8&@D()?E"9.#2=!&B'17;"FC1=EH707AE5=1'#=;GG4)+>A$7D"GF5CD<'
@r7296
GGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCA
+
G*):.<+H.4?AB&"">>&'*C(>74"0,H3-'4HEA=B5"<?2<!/$=#2/5.6(!'->30C@:7**1965664943/#<6=/57<&75#;C*')()82E(<1!2:5:.?>C//%71:&&#/+0EB"0#($-D=(A
@r7297
CAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATNGGNAATAATATATNCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACNAA
+
-F+A?);'-,/=49/!$>D8:?&?/(.A%;"9!9%."<"',3,86,0%?268.'3+:189D66%G*G")?-(3EF,H-%6:@D1*!6H!@#FC$B09A+<,/;!0=-+$89,7A%()D70<$0#<3*-#',HC.D.=6/E/%'()H"-)9+7/)8<4%598G0>';,5E-/F#3C?-=(<0(%>"H"21)(AD,D1)$#0%F.>
@r7298
GAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATN
+
9$HE6;G-")(#;=A9$?9?*+=3<)935#*;)76%@5"C"!!,<*59)09&39/=
@r7299
TCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTNTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCA
+
&H1E8C5;F#(AD?C80-@)0"%9A//01>23.@*+6H4,%+9F&,?H17#F!$!))7%G0<.9,E6(E06(16)4:0<?5'=4@8!-C/D%-/+@,1GD;;3&>FGE!08
@r7300
CGCCGCAGCTGCCGCACCTCATCAGTCCGGNCAAACAGGGACGGNCTGGAGCCTTCA
+
D>'%G&H=,4A%9-*F6%B*1C>E!FAF&G(';*5??.D34,720#(;&,6,.7B>$
@r7301
NCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAG
+
!44#)#(0D,>,;=?7!2=+6*G6##)1@7G/05*?.H9D0#(D+G,)2*78)%F
@r7302
AGCCGCTCACTGNCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCG
+
D/H/#7<#-'9->48BC(%2B-6C-A*(G=H6E/481"0*/4)9&=D7-6FA=12++#%0,-&CB-9:G06,.21C'5.@;@6
@r7303
TGACGCCCGGCGAACTGACCGCTGAGTCCTATGACNACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGNCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGTAGGCGCTGCTGGNGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACTNGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGA
+
92#@&%6!;G&9=1G*.)9:+:)=<-/>,.F<$(G%9FF&;!6B(2@$7C24DG96F<A4&607(5H:H1(5?:&32H2?#?059>0;>A-+<"#(<&4(6?=8;$+.=1/FA?G07F11%%AE(88B!,*!=A9,3$H#H277D,,)#1*4913=CF76!62B2=?!E1B4,*';9A>+B&H>C$@A-2>H"),*%E!FGH&5";#-6+5!/B9)C.<=5*8G9H0A2:'-',*$&0E!HG':EA);GCA962+/)$DAAG*%-;9.#
@r7304
GTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACNGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAAC
+
(%H'B4>3@/@-/2E&B6GG,6+'<(),G-<8C,'F.!<:7$21;='C-9G9A<=-5=5D@!6%%9&!'B96CD6,F-*:(2+0
@r7305
TTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTC
+
7;:;21H;,$7$5CF:(@%+;01CF0:H)>0#"/?H6*,(7,FB5!;/?++H:>&/7-%<*AG?D1F:&!HG=G;GC
@r7306
CAAATCCATGTGGGATGCGGTGCTGGGTATTGGTCGTCNTGANACCGCGCNGGAG
+
*+=*FE7F,,/4?>+9<!C'3"4+;6BE1#9;E;A*/)D3".','&#G3624A5.
@r7307
GAGTGCCGGTGCACATGCGAATANAGTTGGTATTAGTGCGCACCAGCATCCGGTTGGTATC
+
$+%(#)$#)%!&*()+'*)%"&#("##"!#'&%)$'+)')""'"*(%*')"$+#*+!"((!
@r7308
GCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGG
+
&3CG&B99D*1'!)H!!-,$*(4$)F>%:=,!EF(8=@/#$!.C/+A@F>829CEE.#9*#3#&9C536*,H!G$@5A
@r7309
GAGTCTGCCNCTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGAGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCG
+
9?;%,@)?BH@:&'44$-!-5F<$2B!>+%,>%)?*)%<3+E/=#=1E53-(16.:8?)@<9&0?*6+F""8H)5B0:+F?A*'>BFE2E!!B.8%B==><&/3E,5H<>EB"-#*
@r7310
GGGTNACTNNTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGC
+
*'&"#%(%'$+'%$$$)*)'"$(($*"&$")(+&)"#)$%*$%!%#"')**)+!%!)$+))"&%'%("!(')%()#'$$(''*+#$")&%!'&$*!!*)$&&$*!!"%*$*'#"("*'+*%""!!%'!#(#%")$!&$#+"
@r7311
GCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGC
+
/73&A-9-8%F!!-AC>-(?/E7!4,43.F'-:H6//8C7(.E:<2H7+!5'5E3$.*&>1B1B&<%D21FH4/:&%35
@r7312
TCCGCNTNACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATNC
+
&%))'$%!*+%%"!$$#!'&")#**!%&&')#%(#(!)+#"!$!"+#*)!('&))*$&!%
@r7313
GTCGATGACATTTGCCGTAGCGTACTGAANNAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGCACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTANTAACCA
+
5,%*D;.0@4*H/C,8.>%(83F:'C;9C%=<.+'>:6*>6#9,8&$"HB@&8$CB<CE)6B0F=D<=3(&=G0*+CE>:5F3'>-D>314(=(4$*;A.%.((:).<"8E%<>6:E;C(%/'3'4;<,#*D)"*8@,#13.51)56>AC5?G.*>H*7C>C.05GC'E-<=%?DD@C135?!C0#7H$E7.7<(3$>D
@r7314
GAGGAGTCCGGTATGGNTGAACCGGTAGGCGATCTGGTTGTTGATTTGA
+
<4/+)5+2&D@D&-=$');B5EE-49=*B2!+'C%&'DD(F+:588:(/
@r7315
AAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATT
+
>;$<%'H1<*:4;4:&)B88E28''$"5*B)F0.0/$>;?)9-:+"(,$+&45*+E?D13&)HC&E>E."
@r7316
TAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCC
+
8)F/7.;(";/*&()+$?G(5.F?@>386$<&1>,?,A7"52"$:,<H-C&=H6H4'()9=(F'!=E=#<B>6F=:6<<7"C"
@r7317
AGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACC
+
G.F7@,>B<*+%",*?C?#,(:A;/C!@=5D(@$;%BF;6:&
@r7318
CAGCNAATCGTTGACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGNGCCGTTTTCTCGGTCATACCGGGGGTTTCTGCCAG
+
%++H4F#GG0<>C##'6/3'B<<.+40@+1/4-.A8*')B8B+1'&891%64H*&6@1"3C4D,?7$E!1#<*<)C:*;'=3F!7<#945-)E)8EE4HC$*3"186#"A1,=H0%9+*D-8@2*8,E0@!1C9$!2@:-5D,/?E3.7-3%H'!0')G%7*-"(.,:
@r7319
TCTGGCGGTGATAATGGNTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAANCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCAGTCATGAAGGCCGAAAGATTTTTTTAACTATAAACGNTGATGGAAGCGNTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTANACATTCCAGCCCTGAAAAAGGGCA
+
?1H84"&8+<+,9A$="9!7,F6"HF=&@D7..6>6!(#(01"%))=!H3E55%),,$2:!!2',!D35G;<$5;2%'5'%30G+G1-5/"/&$BG4*"E#9/$)C6"+'?5>6D'0"7(!$D%5#1&9A;(B7!G-!!G6A0=:#+'6F:DH0$=:H1+9;G'B!G=G.&?#C6(EC73G96G&E$>5)(/$1C?*GG(*H-"*C#CG:?#)@4BF71;/;>@#.2>4-&47!DF:*.>(%=7%0B?4D4)&/?C8=8'%550A5>FB250>"!;-D3(
@r7320
TTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAANCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTT
+
4%)5&H%."CEE'@$.*F<1"C03GG7-3D=*!&G8+F9B4"A2";89FH'*4=<A&-C6<?A/,:!<109@'9?#"+*<C<!9F(CE$(9A#'/3;4:1A.$AD"0@#%
@r7321
GCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTGCCTGACACCGGACGGAAAGCTGACCGCTAAAAATNCGGATATCAGTGG
+
",!A?H5CC*"?&2=C%763/G,:D!44:H($(9@3)6<*07,DE#B?!6D./9#2G3F4!'67&%5=?,<!E4$A8<6"#=;9!BAGG3!/G*:D*/D!??H&?"*8C0#6,B2/$9>2$H!/<<C1%!:.1-#6@,*!59@@AG,23/<G42$CFA/=65F3.8EE&)=';$)79<"?FA'E'9(?%?(9>0G+'7&?C>C-F-?HEE7D00
@r7322
AANAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGNACTCACGGCTGTACCGGACAA
+
586>$*94+@C$3=+!%+"&*4<5=H,58%/4'2F42D<,A!&/1'$%*DB57D%C8((/&8,75BH0/-B+7F(<")D6)(4H%)-':F2;679/,
@r7323
TCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCNATCACATCCT
+
8!7(/643=9</E3*3,9C#!C',!GD%D)BGD$.9%/&"3C;D"9C9*"
@r7324
CACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGAT
+
4+)<G.%F3H===6(4#A*5*$"@$%BB(;$<>E"&9>%#3>!,-HGA,0.)2F,B'@##3D-03.3C%<.&/?/=5,=?*&943,H4
@r7325
GNACGNTCANCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCTGAGTGATGTCGCGTTCCGGNTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACC
+
")$**'(&+!)*%(&%&'#$)"%($++*%)(#!"+#((*$"!!%"$)*"$"*#'($&)(%(((+)$+!*(+"(*$#)&(()$%&%*)+)$$#!&&!!(!)"$$!%)!!&#%%)*#%'$*&#+%*!'*)('%%!
@r7326
CGATTCAAACAAGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTC
+
@5$+$'10,/=47&?79#,"$30</#)?&9=34'>"++99?+E9:472%;(&.:%7@<>;5
@r7327
NGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTNGGTTATAAATTCTGATTAGCCAGGT
+
&14GH0B8.!1A*EC@1F/9"E+=*':3,6DE0;6=,A>4@)<)G$15C5940$5(H:+.B2',<0!*=;3C0B-(050<!31G%DF#0F.22()@$/"8!C;-6<(H95."2E29,@C7F":>$5'>-!@HF"4FF-'%:0.%GD=?61F
@r7328
GAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGA
+
D?@"+-057B)7'!*439+)!:&8,-B/,$GH6.*9'#&H0">-'*@9)HD,3G
@r7329
GCATCACCTGTAATGCGTACCTGACCACACCGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGAATGGAACGGGCACACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCT
+
($E?$-3&-$BF+<2(874;$.9<G!&$H7C2/'?)G;D93C'$*H/)/E7EDF;.?;"$4-%2G53&+.5>!7#>;)2F+4:#?10G--FH%?3<EC/>&"(F9)8(.C11@D.9B;'-/%B+:(,'-9<1@8*H--'$:!AB<2@
@r7330
NNNNCCATNNNNGACGNNNTNNCNNTATTANTACNNTNTAANNCTGNGNCGGCTNCCANGTTNNCNNAACTTCNN
+
""!"$$$#$$!!""$$$""##"$!$!###$"!#!!#"$"##!!$!"$#"$#$#"!!$#!$"##""!"#"""$$!$
@r7331
GAAAGAGGCAGAACTGGCAGACNACATGGAAAANGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACG
+
E736<E';1/B,.AE(($.9E)&0<:4.?;:=,G/7:..GD6%4H6=@.">H:;3EC%#4!5AD/$B526D"&%$F7?B0-*?H055'2
@r7332
NTNGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCTGTGGTATGACCATCACCGTGAACGGCGTTGCTGCANGCAAGGTCAACATTCCGGTTATATC
+
#($+#'##*$!)$*!#*!*$((*)')#))%#!++!*!$&+*%($#!'%)&%*!'+#""()#)&('!*&*((!&!'!!*+'#+!+())($!$&)$)**$'!&
@r7333
NGCTGAATTCATTGGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAANCGGGTGGCAGGAGGTCGCG
+
'&64$!B.<=BG:B)?1&3>4-6&)20C-,!"$#C0"+D!-'!*.#+@8+A$'1B//".!09B4F)/+,#.>=4@+G
@r7334
GCGAGTTNAGATAAANTAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACANAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTG
+
-56D),-2=('9(0!<>;*;E,A6CF%=;/+7/D,'0#H**,2&<*=>(F*E'((&;53E%B,H12-%H4B5CD'43BDH12!=<.%A@*?4+++D2,-1.A8F"6!#03H.%5AD!D;192%,93E"@*@,GH70/6@5G$=H4+%E(&:);2
@r7335
NGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGAC
+
(.EFD482'-+"/AF72!BF+EB0$2BH#%3EB<G>3AC?E(%D8C"!3GC2.%3.&&@
@r7336
GGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAAAGGGAAGCCACGGAACAGCGC
+
*2!B%@B$/@33HH98)+!9+:6*A<0$H#967)=9D2!EC9;5,D*</A<C1>76&AG%*6AC33?>#A
@r7337
CATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGNATTTTGCAGACCTNTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTG
+
:44*<H+*AH)>G?%C'.15!'AG1@$1!74)"9*;58F/CG"9'G98:>7(E%'-)0&'?8$@&230E%CG>1"3$50>)++%H"(5>=9F"H5&-/&4/C0';2>,1%D$>,%9C=:(F@,F)::F<%)B(6AB73EA38?8B7?@4;;D<4:3*HA,-&A'6$EG5!AB@%E)*D:"*-GC1+!;/@-.A-6-4+:8C%2FBG!FG8'6&4+AA-2F'.F1"4:AC&4G53@'4EA:<@A
@r7338
GCGTTTACAAAAACAGTAATCGACGCAACGNTGTGCGCCATTA
+
1!E$!A/62;-E<F3.1<>1H;A0B1A0:*B(/9B&30&?=6+
@r7339
GAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAA
+
#+%+%*)(%&*("+$'*'&%&*%#+)!"'+#+'&!+#)%++"$
@r7340
NAGCGTTGTAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTAGCCTGTTTTTTCTNATGTTCAGGCAGGGATGTT
+
#E+%8:#7%?8(5)!3>GH?*A&'9!8<.$.G>16#-G4G/%4(-'5DB).F/E&.D?:F;.E!$"0?2E.A6<C1C:B7@%6,HG<<2"8AH"9=!..-@>722-6H?H4/#.H.%5+!+6E;$F<5B
@r7341
TNNNCNNTCCANATGAACNNTNNAANNNANNNTCTNCTNNGNGNGTNAGNGNTTAANNNNGNCTTNANTCGNNNAGTNGCAGNNNNNCGTNTTNANGNNNNCNNAANCGNGNNGNNCNCNNNGACATGNTTGCNGNGATTAAACCNCNTNNNNNTNNANNANAAANANTNNNTAATNNNNAGNCNGNNCCCNNNNNCNNNTTAANGNGNTTGANTNANNCGNATNCNNNNNNNGNNNNTTCTATGACGCNATATNGGCCA
+
""!!$"#!!$$#!"#$$#!$""!""!#"#$"!#$#"#""#$$$#"#$$"!##$"#"!#$"$#""$"$$$$$""!$$"!#$$#$$!$!#!##""!$$"!$#""!$###!##!!"$""#!"#"$$!$$$!!!!$$"#!##$"####$!$"""$$$"!"#"!"###"##"!#"!"!"#!!##!$"!$"$#$""!!!!#!#!$""$#$#$""$!$#"##!!!"#$!$!!#"##!!$#!"#!"$#$###$$"$#!"#"#"$"$#!
@r7342
TCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAAT
+
1?8.""D+86?H$A2=66#,DD-EH$"?3%!%$#;)(!+G);<B058H;,F3>837G0'9/!?$2-51G+*
@r7343
TCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGTATCAGCTGCTCAGGTCGN
+
.//G,1AF2)!5-*!E@C>;**-A<('/?3F*,0@3AH63+@"2-5$@CA;$$E.)5+.G>8;F<@A:#5?8+3$1$,8+4).G'41F<''0C2<EE)525,+:1G6H=1H##!+022'0(A892>&+7.BA6&A1),C7>4?55-9=/&9?,9.8B=85;42AD?>?FF.$1*9,CA?'#23?%+G!F82H?F@8$,:%;*
@r7344
GNGNTTTNGAANCCATNANTNCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTG
+
$$'$$%&"$(($$((*"*!'"+*+')%"''((+%''*(++()!+#%!$*$"&'"#($!#$!"&+!((+)!$($($+$%&&*!*#
@r7345
GGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTANTCAGCCACAGCCNGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTNACATTACGACCGTAACGGGCA
+
G.@-F29>19#A9A?<>=/D!,<'CF8>>2C@93!&GGE@*;!:<A+-7+C:#9FG45.?4D=8#8!'F03?,4;(D39(2-$".)G0F(;;%-/C&C1B@!!C#-;H6%+$%-%&*1+(C+')7<45F5%A!<,'*=/A1H.3.H04!84'!4&#
@r7346
CTTTANCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGCCAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAG
+
C!,2A8;*B7C7%?61/G-FB*'C.9&9#C/!5E;H@A;&-*HC87/6,04'9!E7D8,?@?'9E47%?#DA&=/!F)72@2BC,,02<$B!$.?/&)'CF#?B5BD1?D=*,-+2
@r7347
TGNNNNCANNNTNCCNCNNCACNATNNTNANANANNAGANNTTAAATACCGNNANCTNTANNNNNTTNCNNTTTNNTTNGNCATNNAGNCNAAACNCNNNNGNCTNANNNNG
+
"##"#"$#!!!!#""$#!!"!!"$##""#$!"$$!"""$#$#$#"$!#$"#""#$#!##$#"$""!"!$#!#"!""""$"$"###"#"!##"$$##$!""$##$##$!$"#"
@r7348
GNTCNNTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGNAGGAAGAAGCCCGTGCCTT
+
*#(($"(+""&'#'('&%**$!!'%++)(+*%%%'!%)!"$'+&%(&'$(&(%)!#%++"
@r7349
TTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTNAACCCGTGGAGGACGGGCAGACTCGCGGTG
+
G.1'!>$*)1<<D*3.3&=3&&!A=-367E.;;B:-F-8>*"7>,'/40(<G$'!1<?0"'61F24;
@r7350
GGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTANGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGG
+
*954))EG:&29+9!$H3-7F<+,4E-!9D<9>?3!8;.?/C%7?#$B'<<4+"GF>)G'*=(-$;(+*G:5;4%7A"/&;<";D<"<F4416""('H#F-0$;8@)-139?F!5A()254=,757.1EG-6(,G>8%(62?;,FC:G-&D.E,@D1;;<1#H,0E4
@r7351
NCCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCG
+
!>9%.F73D*5,F/"781H>)5,.8&G67)<3=?=#65BB1"*5282@B?A4>H6B43>H?03H55;B'&3%!00@?(A;HB!5?=;$.5$,4*D
@r7352
TGCCCGTGCNGCACTGCATGACCTGATGACAGGTAAACGCGNG
+
,A-2%EGA/4#5"4*:!4152<6@?@1!4CG+!H$%-E1;.0?
@r7353
CGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCT
+
A;'+C'@8E'D<#,CEF>*2BA:!54,5/4&'):/*!=?A8A&/@/G5(.8H&*02DF&3HB5.=-;G>"?C1F;F4#4C&H"*"3GF<H;E79BA'FD%AH7
@r7354
TATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGNGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAG
+
E=<*(:HC0)H.:>"D%G!'E$?0%)F6=9!(-2G5F>/+6#31AFC,E"B+/H<B$5="CA,5%0%>G-@%9%:7@,)C8FA2B#F(:=A2G%6<@,C<A
@r7355
TGTAGTCTGTTTTTTATGCAAAANCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTNGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATT
+
7;C.'3,./:%68@"6!#D;',1,33(4=-?#-&%4F:</>/D#/A#0AB439*H&.591B.#1=F.3836#3@1&E5H';*>>9;+D?H3G,51=9A"H4/44&#1)C)=3-03.;D=FFA2#(/0'FGG#6A#09C@>D1,&=FDG*;D73DG04E@AB<#
@r7356
TAATGCGTACCAGATCGTCTGCGCGGGCANTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTT
+
%#!>8,H<<?B>0-'AHF'7$7E671=56:H:AF9:8?*)$,96.&7-((0+<#=:<&%;42<5!3$72A@<<6;'-(H':&E+B5/&')8'/4;A#:6@':,4=0$;3$@72@200>$CCD4DE52;3E;A-A<2;"@:A?5&E.-<?D&.;G5<*#3F'&2,'%B/62!9*;G:HG><0,AH@$H1("%<:-10
@r7357
NACNATTTNATCANGTNNGAAAAGANTNATNTGAATTGTTTTATTCTGAACTAAAACGTCACAACGNTTCACATTATATTTACTATCTAGCCACAGATAATATTCAC
+
!$"!(&(!'$#$(#(%")**#"%%&!%!(*+&)'#!#!"*'*#&$(&!!'%"$#*!(!')&*&!#(()"%!$)#*("!#''(+)($+#'!&#+!(!"&%&"+!$$))
@r7358
CACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGA
+
5F)E/7@:)-4.-;7GG14&7=',;*GA.@<<?>F<)DF"C1$*=+4-.2=2@C87*386&9489
@r7359
TGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCNAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCG
+
1&C"(9C/?4@H$!?):!/G3)#!H>#."?/%C(A;!6&!+)7@+")'1F&'/2(=<&5*+<;9=<#6(1)?*-%*@61;@0.##)10,8/041#19D!F%HD=%G&'!9-@33%3A:CD&?=.AAB,FG67
@r7360
CGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCA
+
?0H5?CBFF<B3@G*2#68/-EH4%2C=A!+D"G;:+>@'H=4578=D8C/'G<7-'D';10)=08B5>:EDHF@(EG4370"
@r7361
GATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTA
+
%C/;G&3<E)&CG<7$$>AHE2F"9!;:>*(<2,$$0?.'H."+-5C76!6@C5>;F()B!EF75$4/HA+%!);(96$,0?GF;6C):?8H=,7C=,?%$<6:7A!>)&*2AA0&0/7B%C<C=7//2D<DAH%:?C;51-:1=EA*".A:@8E?%A+"*"+,#B@/<H</=#/45,.<H#9*29))"E41BB2*4,8$$DD(6E+6HD9,!>G9/H)HH$>G6-D-9=;%9;%)E725&+=;)931E))?28)1E*?'C*+=/(;+8?'>!1%;@@)>ACE'F%/6;&0+B*.9:9G8H0&F2H'20&<-"0*0?*(0:D%4
@r7362
TGCGGCACCGACAGGGGCAGCCCGTCGAGAATACTGGCANTTTC
+
%;0%F803$-@E#F)$-19'.E--=)%/-%5%6B+B'E(+)#A*
@r7363
AGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGG
+
G-#HH8:>$F$<8D3#F0;31EA)$B*'9#*-17:H9@2D;<-60G.
@r7364
NGATTTNATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCT
+
#A#&@)H.84H(G';C&)>3.-F#@-D"G=!E(4)6H)7!8G?6F,%<(4E>5181E-#!"$E18#-4.(!+%D(/73.4F+B'$&@-/E8=2C:*<9
@r7365
NNNCAGCCCTGTCTCCCCCTCTCGCTTTCCACTCCAGAGCCANTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAA
+
"#!+)+$"!$"++(++'&&'")'"$'+)%#!&(%#(#'"!&#&!""&)+!"*$**"*#+!(#"+&))%!+&#()*"#"('$%)'++"($$((#$%$
@r7366
CTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGC
+
B(;,"@.D:<-B)5@C4F871).2!F@-H,;5B$5;D>>:B>>%%
@r7367
TCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGA
+
A@><D%2.47/,!(F@&3E==,%08(>5&H)G<A*D$A@"=A8B&F*G;.=A%B
@r7368
CCTGTAATAAGCAGNGCCAGCGCAGTAGCGAGTAGCATTTTT
+
(,8-,G,3:CG:'+:F3:'@7-9).'G5$D0>31-D<:-9!=
@r7369
TAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGA
+
A-;$,''0*DB$E.C%&$41?)C;.=3/G:H5,*!)+,>+$3!?4%6))4:*./7!6%$$#8*'%1"C20E%)7?H(D3F?%'(%7?&:6@D=16D2D#$=#70'1/1)2DF?31>,*7!"F-)"0HH()414,@/,D83/%5B8:>)%-!?/>7&*$"1B&,EH*7!>B+H068;B+.B:-=
@r7370
TCTACATTACTGAGCNAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGTGG
+
+7)DF.6G3674D>H'*"G-?0A)!'$*?0.3A+2#,<>/BH66<!>!!G(F%7>C@H
@r7371
GCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGA
+
4/*'+8HB%0H&4"2@94G;<F<8@;E3EA<8DD<?$9-?(&>3$+03''!:'#&16?:2*?C?0AD3>%)&(@)=.4$*7>8'395@*(##(7>29/'C=4987>2$-D6)>B000D+;-C63HE#=4)=BCG:.=+)B,58#AD)8(G)&E&)5$3(#1-820$;G2!+G$47(5>D.?-!0G'<&5:&2;<.@A!**B5F)0/&94<98<E?";)A88E,6"<,!6F
@r7372
CCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTC
+
7C+05)9%7;'/085*746'$%B>E):*72#E-F55A8H))/%9)(2)#("('*:>6!:
@r7373
CCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCN
+
8F+)&15FG6DF.#G!#3;51%74!,'B$@;A5@1)8)7G'114!?9(864#"H36C@&><-:/-9*-..(+B4)!0:/.<=<;685D
@r7374
AGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGACGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCG
+
,:(.B:$@F2<A!;G*$=#6EE0-@7+H:=$CCC3/;@3?&1,"8;B,%<C<DCE):*03.249DE,@C#48.<F<#)2:"58+%2"%;-,+'<8C6(++C$&,'"63.&7>,$7,@0(300=2:AEE,<##+1;8F$G*#(7!DH-$*-4H8E#&$
@r7375
TTACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAA
+
#/";$1@EA0<F&586H;4H@?(5":$>#:H?09&26+>('.!C+-C'=450":$8
@r7376
CTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACNTGACCTTTCTCTCCCATATTGCAGTCGCGGCAC
+
60H;.+B;B:(""A.@B2,9+ED.@F@,D85GG,,9+6H&.&<!C2""-D';D,*,;%('C8G4GFF1&.."<.B)@H*17);4B
@r7377
NTTGCNNNGNNANGCNAAGTANAGGGGNNNCNNNNNNNNCNANCAATCGNTNNCNAACTCNATNANNCNGNTTNNNNTTANTTCCNNGAG
+
$$$"#!!!##"!#$"#$$$"#!"#"""!#!!#$##$"!""$$!"$"$$$#!$#$"$!!$$!"$!!$!$"#!$$#$##!"##$"#$"!$#$
@r7378
TGGCAAACNATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTNAAGNAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACT
+
2?#;?&0G8H<:@"5,C36@78<D"G+,E6F82BE8;'D=&!!$A25(!@'HC.@3$".3:-:?>4-B#)=H9,1'A9:CG05C3H';CDH,B.*"&=E#&@G:E5)//@B1?5F67H%,7G0@+CD-;-01%FE'$D%A-#B<H,=6,8H/.F-:)9$H7'.B,;?#)9%"+/0?<&@=;*G%-9>("GD95$1A,:1/332/:>E?71*F9:-3(#?%8<</?#C%F=6+7:%*(
@r7379
CAAGANAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAA
+
&"!&'"*+"*%$++)#%$$+#)+(%)%"$("&!(#)+&()#!+"*##*"#$"'"#++*%&)$$!"*
@r7380
GCAAGTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGNGCTGTGGGGGAGAGTTGTC
+
(7CE&@/&+0G<5+?F,3=3*E7D:=#/G:@*=12::-DG@;D+#F,(4+:2$?H3?5!FGA2C9$H"0@'-0B0E<*71ED14-#&1<(28GF?,%#6%BHE!7G6&;,G;+-FEF5-5:=$:0EB#%+$+C
@r7381
GGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATNATACTCAACCCGATGTTTGAGCACGGTC
+
DHDAG.<C0D'5E?BC<F1@1?,5"D847,>2$;H=3%$2+,'?-("$0:*D9@.F5*2-D.HG6
@r7382
TGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCA
+
4C=@/!2F>?1>+7C/.)#*=.'?@%/F5&"@%!GAC$+'94%D5.&&!B!E:)''-H5G*65D$=='2?5=F9=>-3/#H=#@;&E.G&2A9H,<090C!!(6#&D861=
@r7383
TNCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGNCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTT
+
$+&++!+%%$)()#$)&*)+%!)!!'$!)+($'&))*#))#!%$"&*&+#)()!%$$!!(#"'*+$%%'$'"$#"#!''(&(&''%"'"$$&*#$(++("$!&#%(+(#&*+&*(#*!%')+!(!!+&!))$&%)#*(!)*+!&"'&+)$!!(+&+*$!&+&(
@r7384
ATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCA
+
F8F>B(8<$"4.*1!1,4,6=#4D)%=4-!8<3%G+'G*>95D)5%7)5EG>7?!
@r7385
GCCCCATCTCACGCGCCAATTTCAGGGCAAAACTCAGCCCACCGTCGAACACTTTCCCGCAGAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAA
+
%7</<?;;@7!47F#AA+4<4705<7346+66$E<:)5"*8#54<:=D!826%62,C.33@54(E!7&AF:AB&+;@D:#F>!CF("(*@+B8$*='!71G&>?CE?5#&A<78@!+D2-7!H3,<8H&F;*DB<#&@,@))F?=8*)5!77AG7*.?E#!8=?@C&%&
@r7386
CTGACGCGTGTTNAGGTTATANNNAGACGGNNCNTGCNGAATACGCCCGCGCAGATGATAATTACGG
+
"'&%)&*#'!%#!('''('*(%$#$%#!))(!$!&')")%+'(%*(")(**+"*&&$!!%#)!*&&%
@r7387
GTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTATTGCCCTTAATGGTGATG
+
B>95/FA2/'3+F30+,=H>7#CA##$!=CED"F?-GB8$5&:+G%-7)=0?8,:7AEDA'G2:224?-G(86-DD8+&#A$/3G!*"=7"#&>42!:$"'/<-6G
@r7388
GCCCATTCTTNCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAATCATTGCANTTAACNATATTGTGAGGCTTGCATANTGGCATTCAG
+
56&;:!F>F>&8>(:,:4989(>8(07721G(/1G*-F<,-?>@%D7,F.2;?<+;"&9=D.),(HF/587G*%E3:=0;6:/EC+*>A>A4BAD&""6%+"B4#=7$7EEBE90",5?:&'CH
@r7389
NANNAGNTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGNATTNAGCAGTGCAGCGAACTGAGCGCN
+
!"""&)+$&!+$$&)#%"(*!("')*'$#$!"'#)&%%%%!$"+&#(+%(%!$(+*&++&&(%*")++$!(&(&*#$+'"+%"(+')&)'+'#!""%&*"&!$!"(#"!#+'$$*+"'((
@r7390
GCCAATCGAGCCATGTCGTCGTGAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGNNTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTC
+
*+**+"+#+)**"!(!"+(*&*'#*%'&(+!!'**%)*&#)#$*%%&)(*)'+'+"+"$%(!&%&$#$#!')$#&$*&+'%*%#!($''$("+"#&*%*&$%((+'++')**&*"!$%!)*+*%'!'**''*))*#&"$'%$&*+(!&!*)'%!*$++(*%"&!()$)!)(&)
@r7391
NGTGNGTTTACTAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTCACCTTCTCGACTTNGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTAACAAACGCTTCGCTNAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGNCGTTCCT
+
%&"$$$+"!%)!*'&)"+(&&*)!&#*"*!'$&"!(&'!%(!+!#)(*#*+(#')&$!%*((#('$+(&&!*$("'"*&$&#'+$*$&(+(#"%*("'!#!&&"""&#*+$!&'+"%("##*(&("$(%(**(#"$"+$'&*##%)!"%))+*!&"$$!'$!')&!*(!&*+!(**)%%(+#)+%*$#"*+""%#!*'&!&+!"+##$$&*")$#"%""!#!"*$
@r7392
ANCCTGCNTTCCCGAACNCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTG
+
6>%"<A"0!,.G57@5(4A$0+%,D9-=C*,+9FE<4A<=,/@F*>G5:3=$5%@45>F+*&#>3<@:!!9G:6
@r7393
GGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGC
+
):4G5#$'40@#B$4!%3A@ABA)F0>"::&$,H%ED/E&=E8"6,*@,#>=+'4"->H)=*"(+)H0F7BE@'1++<$&B*
@r7394
TAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAG
+
4C$7,.%08->$).4!+'FE,E4?!64902*<>G&@)4*=*%@>:3F('F*-""0H#$6&
@r7395
ATTGCCCATTTATCGACATATTTCCCATCTTNCATTACAGGAAACATTTCTTCAGGNTTAACCATGCATTCCGATTGCAGCTTGCAGCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTANCAAT
+
0+029AH4.'73'&A;7.F=2$C4=3(;$CH('/(=+C*B3&6,'+>*1F1<3)#3*0&72&G?D>57D$??7/))5;=9!@@0:*1*%@?38HH6FH!."?AA%!+AC*+(5F*&<G#!$$G(E4GH6&<
@r7396
TTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCA
+
CF$76F#<(#:#,=>?B?$'E"!=+.#7E%28140..4=48?&1*>'8>
@r7397
TGNNAGGTTGAAACCNGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGCGTG
+
'$!#'+*""&)%+'(*$$%#(#&)#'%"""&%!(%""!$+!'%'((#%"'&&)(*+'$#'$'#')'%++(*!!((*!(&%(&#+(%)*&%"$&)%&#(")**'#!(!+
@r7398
TTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCTGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATNAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTACAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTNTCAGGAAATTTTTGCCCAGCAGGTCNGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACCGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATAAACGGCATCGCCGT
+
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
@r7399
NGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCA
+
"@A;8E4'<'5<02E!')2&9=HB2#$4&@A66%A$:>H+&3
@r7400
AAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAG
+
B.CE7$$--14A;@2=32738"'H')FA2)5GGG*<2G,:)9?26@?9,E+3?!9F(@3-!<$16>
@r7401
CNNACCTNCATCCNGAACCCATTGACCTCCAACCCCGTAATAGCGATG
+
&#%*%%*%)#*&$$+!#+)*"!'(+)((&(%''%)*'(($&!($+'%#
@r7402
TCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCTCACCGAGATAAGCAGGTCTTTTTTG
+
F,,/)&%E.%C+C@0G-::H#30*#!(8.=4&H0E&1=(8)"&9E$)>$,78$=8:71G1G!/5,5E*+40>+/2B.?*A(7E8&:,!3D;@*(F:6="-<)A&CE
@r7403
GNGGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATNTCTAACACCGTGCGTGTTGACTNTTTTACCTCTGGCGGTGATANTGGTTGCATGTACTAAGGAGGTTGTANG
+
!$#04;D&&2>2F4!'1?EGH>9(,A@:$31&D2A9BEA4#'?@A1,12<5.'59#B+296BB)='-E&<&%1?,2="<<GF!B=7;:-/>A)-=!'/8;A+H?&$08;+)>E4C&*4<3!(%84FF;52:FF$:$0B*@D+86'10.?!.@/
@r7404
CGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCAGGCCGGGACCATCACCGTGTATGAA
+
7C64C;A81C',;5*/@%,.<+B=2EG+@#AGF7&)%1@&*(9@0:(A)274A-&.G7#%C:;;'G)=*.85A@73+F,'@82%;*AE09F7G8'6B3ADE3A/5D*4:#'28;:EA#6"D;;-.6+%
@r7405
GCCACCATTACATCCGGTGNGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAG
+
+2B&.';,$A5CGH"810=:84AE:,'E=*)C+@A(<7F#<26?&<;-8"1,?*GB4=&+#@>A%<=(/1H
@r7406
NATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGNCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAANTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGA
+
)&%%+)'#&$#+!%'#($#$*&*"(%+)%&*$(!'(%()'+(#+)#!*&%$!)'&""!)#*)("""&)++$"(!&*+"$&&%%"!$*$("'"#*)&!+!$*(!)$+!!'%&$+&+$'!()+$!&))"+'$(+''(#()!%#*(*+!($("#(($#&+*!)"
@r7407
CCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTT
+
B@3;C<:G(!7,"95/F.3=C;)?4*C<=5B=0!@H0=6H3%=
@r7408
CCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGC
+
="73*+474-9,?4%?3#?G4?B-1A@H'96C@$3"$'.?'9A,E6,*.$)5:7@@E&E9=B(81=D'6B.B2-&3;H&:
@r7409
NANAGNGANTGNNGANTACGNNCTTACNNCNNGGCCNACANNGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTNTGAGTTTNTGGTGAATAATGCCCCTGAACAGANAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCANGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGNACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGTTATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGA
+
'&!(*$$*#'*!!*("*%%))%)(('#'#*#%#'*'"*%)$"&(*+*+'$$")($*+&$'')$&+'$$#+(%&(+$&$(('$(%'#"*"&**$+"')()!'"&&%$#"&'$)%*!+$*&+)'#!%+")!"!)"#%"("+$")$&'$!&%++&&&'+'$'&+"#+##&$"'")($%$""!"("+#%&*(%%%*""'%&"*%'%'$!"#'+%+"#&'#("%))#%)*'*"!)*%*#"**!$&%($"+$")+$+&('")$+"$+")+)!&(#&%$)%!!$!)($"+)'+*(*$&"**'+('"#)+%"*(%()+')))"$&$)&)&($!)*#!&%"%+&''"'#*%!"$))$!"!"&%$%&((*'("%(#"#&)&'#$%#!))!'&'$&'&+('(%!$*%)*+%()(&#)(*$')&%(#"%)
@r7410
NTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGT
+
,6#A)9+D3""B7B+&GC?55#*/9GB-!C4<158<<@2/(>G8"
@r7411
AACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCAGCGACATAATCTGCGAAAACTGCA
+
-531(;A#$A.-@&9+4*#.#E#,4:22!+.4@A%'@!;53C%./:$A1&-8'B3C!*)<C+$:9AD%C@C'>*3+0<)7HED8"'!H
@r7412
TCTTTTTCCGTCACCCAGTCACCGTTACGTTGTATATGAACCAGCAGGCGGACTTCNGACGGATTCCTGTCACCCTTTGAGGNGGTTTCCCCNAGTGCCTGTACACCGAAGG
+
E3<-;"(H</(':13A/:04>$2826=(#(D84%F:6,(?F3E5:??,@2)68F/6D"*)*7D8CD'G$!>A@4=>"/G":-@7"HB;9>)BC9A:3&:!$<*1!/#<(#G1
@r7413
CACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGC
+
'%+%!!%%*!&))+%%#(*&)"!+""*'&+''+%!(!(+'*'*(%%'$*)%$+('!"++%(+&+)&"!&$#+
@r7414
ACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTNCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGTCGGTACG
+
D0HH.*9&5&+%:F."A+@&:?'BF>.!>:*F'-,$0GG"<B*;$!%><"'/G'F54(6<)$$!288>C$$$-<>"(/*:=7)H0D6((C68>2&"FB-A&:1--=B875D
@r7415
CNTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGAGTCTTGTTCGA
+
%%+#'*'%((*+&"++(&!+%""'#%$($(#$*+'%$##""%""*!###*(
@r7416
ACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCG
+
,$/5.0:/7+-D5?:+'*!G959E5,1="8#)9@C6!2DH9-+-D#F57G')G-
@r7417
TTCCGCATAAACGCTTCCATCAGCCTTTATAGTTATAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGA
+
';)3?<.=6,B!>E-"G4&>?E<BH?:C2G))669A&A*@<>.2)69-C5F*02E%&96"-$9;2"63F5*7=-D!A>2***.D2;$%#;D6;1
@r7418
NGCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCG
+
(%/)1@#6E?1=45&F<F:"-1GC='#;F'=94G84GC?8,GB
@r7419
CTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACC
+
,$83F@?0@,29*%00"6@49AH68&)D,6<GCG9B>@@31$$:(C(%2-60
@r7420
TNNCCNCCNNGGGANANNTANCNAGNNGNGNTANNNCCANCNNGGCTGNAAGATTCAANAANAGCNANNCTNTGCAAGGNCNNGGAGNGGNANCANACNGAGGTN
+
#"$!$"$#!!$"#""#!###"#!!$#$!$#"$#!#"$"$!#$$$#$$$###$$$!#!!!$!$$$!""!$##"$!$"#""!$"##!#"!$!!$"!#!##"!$!"$!
@r7421
ATCACCAACTCGTTGCCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTNTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTG
+
H':2)?6=6*/6H1"%2@H)%'(CD@0(?$8062%B*H;'0,.5)#)7D0$&;.!G)EB)<*G(E3/'&.H6AC4#&CD'>/&>C<0>5'F93B;G,'-@%F,$".77F.A;G.<!AD+;#7A9'%C91
@r7422
NTAGTGCATTTGATCCGTTNACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTA
+
"E2*<1&.E:B/%!-0*-F>419H<3*919<0&72"<,;5E-5C<&79$;#2?0@(,
@r7423
AGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGNCATCGCTGTGAAGACGACGCGAAATTCAGCATT
+
H<<$*C<=68E(:E5F:3C34.@8:2/;*'.)FF3C<!G84://1#!@2:.,4H,:!G5#2F0C)-?D7*.-D*6!*!7#,<1%<=392=@C;7*%$EE8
@r7424
TNGTCNCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGG
+
!'*#(!))((#+$%"#%'"!'&+++'*(&*$(%#!)('$(""(*+(%"$)&('"&$%('*##'%(&#'%*+
@r7425
CTCGTCACCGCGATAGGTCCAGGTGCANGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCANTGCGCCAGCGGCTGATCAC
+
?DF>9@!E+$6@9E6E10@&;%G%+;A1)$-E=*-9($3">?<C?9<G3B'&.,'G//DEG*<1.D#!'/3,*$9A>+C3FH3%.@4/+!)C7G0!A:&$%GE<&9(=#4>=0.04+7==+;7"6D3G(-+(A05:74-6-,&#,G3;8+3G3
@r7426
CNTTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGNGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCA
+
8?1"E@,F-?'?*1;2&>;D'&#+87&+"00"D*H1ED/4"&E);GG!C2?'$89/*AC4GB$8.9&"!#E-%!0:%*(EA4<!+A!43-1A-71*821*>*#&:(15-9A"7.8-("
@r7427
ACNGGNGNCNNCCANNATNCNTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGNCCTTTGCTGATGCCGCTTCTGCGCCGGGGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAA
+
*)'('$'&($#)(&($!'$#+&+#&$))%"!!+"'#&+!""&&$**&*+'(%!!+$%+#)))$**))))%")$*$"''!$*'$#'''))%+%!')*'!#&*!#($"++)%!#!()$!%!!*'(!""$'!"!*"%&!#!""$($')))!&&#"(('#%&($'()$&+!'(&
@r7428
CGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGANA
+
:"1#.=*'8B:F62C<$$='+@-+H<E914,-A:D>-$./39H9DB)0E.DA6)(&C#8=;%!->D%G=C72BC2"<=?D:2,50BA7+!E181=-)7,?(A>)+D*HA<7.;(<%,5(B(:2
@r7429
TTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTAT
+
/:=3C.,C?..5.=4D84(&A=GDE0.4&8)F=,5/?H@C>8C4!F8=&@,=>2$8&B>5D7
@r7430
CCAGCCGCTCACTGCCGTCGTCCGCTATTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGAT
+
.6?0F>4+.)44C*87G'7:8H:/&B>-;H=,*8;:@A94!/&",/2<?3E"7@=?93D1F>:-71$EE)"F51DE&;$?+/(*!D%?C22)7<37"-&
@r7431
NAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCG
+
%,':#;737(0E&,%*B0&'@0!'@C(;>E6B<+!5B-5B>8>,#.@$E39<A=B>*<33D<-,.G*=/2C':?(D8($F?@9E
@r7432
CCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATC
+
)F7@9/1*4;166;+:=322F;@.6/6F<;@*5244!&D6/$+/8C+3G
@r7433
ACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCA
+
415"(,)CH4?;#/F//.6B%116=:+474DE#+<0@%.-$CD.H#$A+5-5241E,)';D5+'+<A$EH)0-7!F'$B7F&#*E)+$5!'G6F'3HA6:5+-+4D*%@/@-+6B5?)=@131>%;F,/1*B11H-H20>GE$@9?<#%,2A!#0<B#"#C:7*3
@r7434
AACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTNCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGNAATA
+
9C8=CC6FDC#517+=2CF$#/4?AE72:E228D/&;/A1%5-5#G8(41.-)5$!*&<>+D==&;@A>6(%#$5,7970;G
@r7435
TNATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCC
+
(!.6"A06347,9$@C,G!?4-(':!:C/6BFA:*')+FG>::5?3,C;F!/$;68C7=6(:'"&-$+
@r7436
NGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAAGATAACGCCAGCAGACTGGAGGA
+
(##$+&+%)%&"*%#*#(*%&%+)!'++)"''%)'$+&)&++$%&""')!)!")+'%+'*
@r7437
GNATTTNTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAAT
+
'"$'+&'+'+')$'$$'++"#)$&!#'")&("&++"+&(!))!")''%"(&%$*$**)%'"("('&+(!($"")'%*+$&$'#'**&)!+%($#(!##+"#)!!'$#&'*')))'&)+'$$(''')$"$)*'()
@r7438
CAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGC
+
&'=8A&='C&;;:6>?0*)6"G@(CE8B19=F)4(@05(-*E=D;B>=.7
@r7439
ACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCAC
+
29>HBH958';3+;2!6-FE+/C@'.$?:"<DD5)88A$C%<?:5#*%H-(EAD"(B
@r7440
CTGTGACATAACCATCCGCAGAAGACGCAGGTGCCGGCCATGAATGAAGCCGTTAAACAGATTGAGCA
+
)5;68(<&H%CA:F&7;5?3<?"0!F*/&8*:>"5G30E1&6#8281A-.<C',<6..!.6:%*@3,/
@r7441
CCNCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATNTGTCAAACGCCTGCCCNTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCNCGGGATCNGCGCACCTGCCG
+
AH3?D='H?>@1';)";B(=?C5:*B;4".GD")=$350&H'!@8@,,<C.FG@191.=$6@"+G)>9;&F=E3?6&F=!22-2,,&1,**.&/-@,5:!>H1"1.EG>$<)F=<7D/:#H4'!''14>,.!H;<,$-EA<'EA"=.E9:"G0<F(@%$8
@r7442
TTGCTGAGATTAACACAGTAGTCAATGCTTTCACCTAAGGAAAAAAAC
+
+:DF:'A?&92E7'E02FH941+.%(38&4(.8B@1+..!6C/&$27,
@r7443
CGGTTAAAACATTACTTCAAATCTTTCTGTATGAAGATTTCAGCACGTTGGCCTTACATACATCNGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCANTACTANTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAANCACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGCCCNCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATAAAGTGCGAAAAGATTTATGTGAATTGT
+
'+#)$&%!"!'&+!+#&'%"#'#+&+)'&###'&*!*")%+&&%&&(%'&)(*'!*(&)*"))#'&(&)'*$&&'++#(+(*#"#!$)*%('&!*)*"%+")"%!!%%)%!!"&&#)')*'%%'&+'!((('"%(%&%()+!'**)*%#!%++!&"(#"#*+%&*$'(++&"#(*%!)*#)'%(+!)('+$&!"''"+"#*#'%!$(!*"&!!+)#"#*+!##+'!'+")(+*#++&+'!'("+%&!")'*!%!"++%*!%&()#')&"(*#+*#*!"&+##%%*!""('!&!(&#*$*''##'&'((+"$*'*%
@r7444
ACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATAACTTCCTTCGCC
+
9B(?B$/%#;G$:-47*H+4'-+,)-03.9HH.'H4"4A+7A$>;H9>2<3:D=52D9(E9H#@HG16.1E-!E#+/)
@r7445
CCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGC
+
B=3E?"&C!<;E24F'&%+B1/(38922%"-01A3H>%62$'%.,
@r7446
AAGGGGAAANCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGCATTAAGTCGCACACCC
+
DH,29-F;4B+-:%)67(C4061GB(<4!H$.-41>;A.B-H"?$>G30,)51'F4;=.0H9%9ED#
@r7447
NANANATGAGGCNNATGAGTTCCATATTTGAAAAGTTTTCATCAC
+
#&#"")''(&*$$('&+("!&+!"*&$!*%+)%"")!(%!#)&!"
@r7448
CAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGAC
+
='.B((3&E>25,B0*>!<1CH6@0H29BD8.%)8;:<BG?+4/1.$4+.5",4G(BB%%;/'G0<,8C*4*>H=2CH&?./9*$8;-+F?/8<-/&2BE!F.
@r7449
GAAAGGGCAGAGCACCACGCTGTCCGTGGCCNTCCAGCCG
+
++)A%>(F')1</&;D&1D)*D!83+3>'#"=8!1+'"8?
@r7450
AGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTACCCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGT
+
H42,7:$CC4D=!04<B<;*42!2%;H+;=F+;C*$?5'H),2GB',:@@:&$F?<F-;#!6',2>':>>#@4>AHHF%+368,0E0B%(,&&AE9H*H'+7"=<1)=A8*2B%?%E,#9B<B>">5/D6@$)'$=8C3E@-B")$&/3!'*386D*H/%;;H">:2:C4
@r7451
GGCGGTCATAGCACTGTGTTACCTGCCTAATCAGAATTTATAACCGACCCC
+
"1,81-H2,-($?D)%F$87==68F%:!57D%=F>/"<"02;'DC&8927D
@r7452
TTTTGCATAGTGATCANCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGC
+
F>/?E+/CABC+3$A8=,20(+#H$//0FC??7>70!'=#?+<@9>8,'$G+;@0+C@3);"5H==($,%)?/%?1:*$*:+8'1<F?
@r7453
NCAANCGNGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACA
+
*!')!)%+%"(!$*++#((*"'*$')()+)()#&((*!*))(''(('#*'")'+*)*$!&%)(*&"$!"&!(*$
@r7454
GGTGAAGACNTTGCTCACCACCAGGTTGATATNGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAAC
+
)!(&'*!#%"+#$!'*&#&*+!'(&$""#"*!#*)*$#&$(&"'''"("#(#+$%"*#)&&')+())'%#&)$+%%(!$)#!%+#')("))+%$#!
@r7455
TGCAGGCCAGTTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGNTGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCANCGCCGTGCTGC
+
2+*4G<53"'-3>/&$D?E*H@+*-8AA:!,(BH'3/27F2G+./3%3B#9+)(1A5C!,>?H"H50"9:<*-(%6%<@#'9G<1'!4F#0+F7'&B.3"*9E25BB>7E@%52*<%=3*"GE*F9;&H#'2!>0E@$:1+=9'%AA(&<6,)&4
@r7456
NACCNTTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACC
+
"'*$"(&++*"%'!)(&""'!&$*!$+"'!'&&$'!""'#*#+"&#%"#)'&%!)
@r7457
CCGATTTCGNCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACNCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCAT
+
%:?(H'F8/0,H=HA5>.1>952=;!-3@$5='9*";C?1B..H,/-C70#E:!5C2:A5G-7.,HB@-)FC/(');469FA72;09)3!)0)4+;
@r7458
GCAGAAACGACTTTTTTAAAGGACGGTTATCAAATTCAAACATTAAT
+
3#=H&'G3"'G/HF7FG0*2-F(,812FH+53.)>=<3'+'@13E:(
@r7459
CAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGNGAAAACGGGATCACCACNATGGAACAGGTTAA
+
A=D=64-E6(@3CGFDE#6"5C>?C@CC9(::&8H(BFFD6$H-A25?0'!$#$/:D5<A5:"058?2;:GC;=07%",E
@r7460
GAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGANTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCA
+
F/?=.:%3AHHB/*%63;)A,'.<G,(+:7><!"3<'+'EA21"GHD/G"'2<:H?62;8<87F7%$(#B2C)1!$B>0FE4=;4"=9#>*D8F=;5B*9@59""-4A#.56):)#
@r7461
GACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCT
+
=8;9$D20B5G:D6'/4=0:B<#H7!8-E?1"%=(:F46FF?BB<419550B8&9;.@+>=2AE-?.@8FB*418B$E,'@7?H%C>=&B+12'<%&@>)22+%)20+A"
@r7462
GGNCNGAATCCGACAANTNANCCNGATGNAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGNAAATCCGCCTCATCAANAACAGNGGGGCGACCATCAAAAAACGNCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCNCGGAGTTCAGTATGTTTCNTCGCTTTATTACCATCCTCAGTTGATGCTG
+
&#$&$##((*'$&!)&$)#"%)%$)"%*!+'!'(!+(!'$#'$&(+$"!%'"$"!$#+*!)#"%)&%%#)!(*"&"!#($#*(+((%))%)($'&(!)$&)("#')+&((!(*&)+(!+'#$""$'+$)&(#%(*)#'*+#"!+#"!'!)&(("#"($&*$!&(!#"()'(%$('!+($#(")%%%*(+)*"$)**"$$'(*"%"*('&!'!(+%#(*)**&!!#*)#"!&!+!$(*')*%+&!$)&&"&!"&!*(&#
@r7463
TNTAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCNGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTNGCTTATG
+
&%G+9<1)HED-:EAA6$&H'!A6!:)487!7&G<9'##>E&#>-8;##=<1-*A".#&H8E"<10A+34/=%.39#F*<-<H8+.%=FB83.(#:@!'19B'-./-$?=:"792.&(--/0.:5F9)
@r7464
TNNTNACTGANGNTATAGACNNNNATANTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATNAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATC
+
%!!*$&"(')"$!)'()!)(""!'("#"+)+)(&+""'+()*'#!""$"%$"'!!+)!))%"++#*(&+%")#&+))!#"*)"+%+#'+$)&!)!+""'!**+#!'$%$&$!'+$#)'%++('%'")$&&)""%'%%"!%!$((*&+%&+#%#+#!&"!$+)$!$*&"&)*#!)#)%###!!#&)"#%$((!()'$%#!%+!&+'+%!(""$(*%(!(#+"*''"+*
@r7465
GACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAAC
+
>6234A.&.!)2<7?1E7<H#"<DE8F8.GB7AFC#FD%,*0(#E"DHG$F?,0/F)-&+5>$D73
@r7466
AATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGNACTGGAT
+
,?/5;*BE-(0/9*-H.$0=*65&(>"00C&1F2&;8?/;/DD0@H)'-8G01672!>FC!6;$/$.%12@%626H'$2&3*EEA))4F
@r7467
ACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGAT
+
/27!<;6689+@:=519H)4D'$=1=1.&"?,C566!C&0H4801,;G7%<-*-EF(4-/?1#
@r7468
NGNGGGNTCANTGCAGGCGCTTTNGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCNGGGTCACTGTTGCCCTGCGGC
+
%&$'"#*&(%%*+!+#*)%+"'%!'$)'+(""$''#&)!+&$'"'%$*!*"%!*)$&)%&+*#&#"!$')+&$(#&#+++&
@r7469
ATCAATNATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCNGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGANACATTTCTTCAGGCTTAACCATGCATTCC
+
D*5E(H.F1504'?B<D/+B(D$**:?+5(=/<=;H!85H2.@&.*5@$$43:.7*D)+H>8D,03H+9=2A/4GG98E69:@))68H7@G))2/7.F2D#-HH*#DC1C3F#/#9@B<71$:,:C/CE4$*,=5HG6)%CB.809CE"@403?'G?@'BB%5G4<0$4(F?*.>5448$%01,;@1>&)&H:C/@!!@8)0+!,:+(DD05"/"D8C.#7=>H(0&+?0#:;$84D#*)!DF!B@+C1)D!24"$,*F(;&1#-0C1/9!45D*?&DGA4<"#A32E3*1'"&#'9"$#$@9#+4$87+3@()=*&(@8<=D==2B0-&$=E8%-+%4G:$
@r7470
GCATTGAGTCGATAATCGTGAAGNGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCC
+
-F"7&978&B8#-C((5,=&+F,H3A&B7"62%-42"2>A?;9>-<@?5G8B),23
@r7471
TCCAGAGCTCATTCGAAGCAGACATTTCTGGATATTGTCATAAAACAATTNAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAG
+
=?+:<5#%#5(%F?)7.&*(C1.2/+01;0./B3DD+:2);!:3G%,3G7$2/#6/9;5B:2B1:'58*6<*>)C1!2E0=/267)/B9CF0/G$6A:/B)(B0E$;=B44%=
@r7472
CGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCNGAG
+
+)/;$B0A9A<!4?=7,.2,0!3CGDA1)4#G4!)B@=C<C,,8)@3-":H"C+@/(76-'2-A@:78
@r7473
TCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTNTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATA
+
3A65)2H&*5-?D.)40"5<==5-;)H<%>8"#B+3"F'$34G@CG%%0"%CE!6HB/005G#-177'7!"0@C"?(0A)D7&-=-C+3$/)353;E&<4:1$9>3@89)G1+()7G:'3,)'+2!+G&B&D+'%.-FD>,'=?7$).G2%:#6>E%@C*4+$1)A.#728DG@)#22D2&020'54A/#<C%&#@-.1E"H>!*%D#4@#%):561@'G5()B-6#,
@r7474
GTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTANCGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATC
+
&?A:.G@,C&<9HFG!$H!$7*>2C0.:)<+,::-,7)B0#*:%A.!+=E8,2(84FG,+189";=F$:%"*?:<H.("'#G&E,?40($FAD<FE
@r7475
CGNGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTNCAATGACACCTCAGCAGGAAAACGCCNTTCGCAGCATTGCCCGTCAGGCTAATTCTGAATTCAAAAAAAGCCAGANAGCAGTTTCCGGATAAAAACGTCGACGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCC
+
!)&++)'$*)$%*$(#(!)'+&++!($+$(&())*(#'##'!)#++!")+(*#&+$+($(!%!%)#&(%!$!*&&$+*+"&"!#'+!(!*$&!$"!++)&$!&'*!'"!*)%$'$$&)(!*'")%$*+%$#)'$%"##%""*$(+*'(*"*)()*!&)%$(&+($!#'("+**+$+&%'($""!$%&!)!#!%'%&""$#*($+#()*#'#(#"(%$$(")'#"!
@r7476
CGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTG
+
1D'&34318AB6CFC,H>G$?!(+1@8@%63?3/(2"3#;7&C'&1'>;H6C0'33&0E6&>H)-=2HF+".//6#>G<>.*D3
@r7477
GCCCTCGCTCAGTTTCTGACGAAAAGCCGGGAGCTGTGTGGCCAGTGCCCG
+
1",@71!,&5F)#,,:-F=,4"+#4"31(113A'E5C(<&<(:<&&:0)%/
@r7478
AGNTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATGGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCA
+
!#)+'&"'+*$)#)*&'%%!!'%*"!#($##&(!&+##(*#(&'%(*#+%(##%$)#$$+*#$$&!+*&$+'$!()+#%(!%$!$%"#&(*"++)%!*
@r7479
TNTCTGANNNNTATGGTGATTAAGAAACAGGCGCTGGGNAACAGCGTGGTCTGAGTGNGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGGNTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGNGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGG
+
!"&$&&$"!'!+++'+))*%*"%'&+($*$&(%%&'$+"$#!*'!%$"%($'#&(+"'$!+''%&#))%#)*)++')%*+)**(*#()+"+*+&!&&&$**()#*!%%*!"&(''%$"('!")!!"#!*'$$###+'$!&*!&!"+%%)&)$!$&(($***$%*+*"*)"%"#"+'!(#!%)%++#!$+*%$)&&+*'#%(!!'&#$%'&%"!""&)+(%&$*('*%!%'*"
@r7480
GCCTAAAGTAATAAAACCGAGCAATCCATTTACGANTGTCTGCTGG
+
=::6*+B-0"6+,1$#<<.-:,894(1#/H'$FF*C+63$D3H/>%
@r7481
ATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAG
+
@0+/6=2-8042:.@CB1;H)'2%8*&E==<B4'$23(8*A6/;C)D4>-H3
@r7482
TTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGNTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTAT
+
+%$'G0A13-!61B"%$/BD#@?AA6A>&/+;8EFE$25HG&,%EG!$#:A515!D>,B-#:*H"*>/?;(=4*2C"&2=.717!G#$,D*50"G*=4D#4:D62%6+,>"*%,!3))!D42&0",*9F932;&.<&)";8)6<8@'2@2%!5(45G!!
@r7483
CTGTACGTGGAAACCATGAGCAAATGATGATCGATGGCTTATCAGAGCGTGGAAACGTTNATCACTGGCTGCTTACTGGCGGTGGCTGGTTCTTTAATCTCG
+
.&#'*3-/=?D2,#;+3>8#B3D619E5?>59H$G$%$!E%/C26!%><'B'#H:EC/E/#),#8@.96;A$&&9C>8G2A3(H?:0AB8/02%>FG=79:%
@r7484
GCGTCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGTTGCCCTCCAAATATTTCGCATNACTCAGAACAAGAGC
+
',8-6DGEB.'=F0,)/3.$(F6>%'/,:D6#@H",@)33@0*84)-$G)C"48)=)@6D4!(*:?3=3<4C>:
@r7485
GACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTT
+
EDE@C%'8F=#B*/E2".-*6$=7#4@!9C<$#B3@?>D2/(;$G6/)60<F<6$>9C8';%*?4(71#
@r7486
ACTCTNANAAAACTTTGCTCATAGGAGATATGGTAGAGNCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGNTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCGACCGATTTTACATA
+
#"$(*#"!*$!)%'+"(#)$#*%&&"")&$)!(+*&&%&+!)"%'$!('$'#!)$+%*$+)"("'(++")$!#&+()&*+&$%*!((#"#()(())'!)#"%')&$'+$!%)#**&$&#&'($*!##"(!'")'&*
@r7487
ATGNTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTCGCTGATTAAAACAGAACTGCTGGAAACGTAGACCGTGGATTTCNGAGTCGGCGCACAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGC
+
@5C4<6E<<>+-.!$F&=2<,=9;">&!<<09<'*&)5-58+*A-HD%4<++)((D.EC!/21D!;+G$@$;&4EA%=<%=1=).!%/0FC+<.A33,55)89B893C@$).%B=F9':D@0#@:A?CC>;=?+<:G-77;-F.,;7)C1CHD"F-2H?>E
@r7488
ACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAACAAAACAATTCACATAAATCTTTTCGCACTTGNTCGAATATTTCTTTAAAAATGGC
+
!;;GG8'D7<5=?5!<)3F=*A;%G(:1)6G":>C6+3D5=G#0?)G)C!/:A?9#,&"7,=)&C3H(.><G%E4##?<==;1@3'1:!-9G2-+<G,B+$:"953!=#*4>,1;-@)7>-3#<A
@r7489
AGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAA
+
/1,G228",C@,B;1+8?C->0642B=6CBE#9)666,73$,/D2;6@&.01+)@''=0?>E%E3H*(;#D3;$.GGAF@2329-$GHHH9%'#!H=-#2*&E70,-:4#F&B3F!@A""1+@#;)@7A/E/E(DD60!=G46>7$"0"@?$1C#-!9#EB?;1-%$":.5H=
@r7490
CTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTC
+
.!E)?G7;0H.H*C$!4/59"@7;,/*9+:%:+4=7-#;1+,+(()&.72*!4%F@FB'8-)$8G3!@9-/%:%9&?!+)=F)<'E!B9=@$2/!2HG6(2-A7A89;.*=&,E8C<E
@r7491
NCGNANCANACNGNGNNANCCCCCNNNANNGNANNNNNTTNATN
+
!#$$$#!$!$$""!$!!##$!"!"!!!"$##$#!"$!!"$"#!!
@r7492
TCTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGT
+
(849%2D>#,(?0<!C:#)=<83,H@=7/)@GH#-!;+"?.6>,@!'$B9&:=,4/C0?/%H+,/D"9#188B'0"2*A,
@r7493
GTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGC
+
'H.&***=.6"09*7;>=!..*F$08#%(<F&=,E2$B7>7:A$/83B8F&';<$69BG$'C
@r7494
GCTCTTCGATTCAAATTCTTGTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCNCTACAGCGAGAAANCGGATAAACTAT
+
:=.F*GA.@>$)>GD%)5'!#@*FF'%5:'">@-+E4,F<F<4DH76G$4(>>"6?-*#2/CF<5)6%D:'.+55883H2G"?A'(>/4A?;:#2%-;HC+-''(B7'-DE4GH(D6;@70)30$:377/=9A&*4
@r7495
NATGTGCGGGAGANTACGCAGCTCTGCTGTCACTCTTCTCNTCCTCTGTTGATTGTCGCAGCCCGGATTCAATTGCTGCAGCCGCCC
+
%'*"+&#"+*#+'&'#($%)#+&%$%"'"#+'&(+!&%*$&#*'*+!+%%$$#!*"'%&+%''!'+&(+%*'&$)"('*%&"'"'#!
@r7496
GACGCTGCAGCATTCGTTTCTGACGTTTTNGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGNACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGC
+
H>/;.A1(<01$1,'7"8&#$5<E&CG.H:,;,0&AB#!8#*#7B%/6>0)'C468%6(=)+;=8<(7"/9>D7G.#EE(+/(#4@?3@>9".:"D1FD:3.:10B%?97,-,"!3&,G+F?&2B+<3B!0+/=E#2*0F61A!.92.!H>!.;*$F>&$@80CG):.AA2:3$=5A(62E>F(H'2!F3G)'(4!$C+*(@<8'*="'&2EH.*7(,D6!D>(&1*
@r7497
TGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGNGTTTCCTTCA
+
:79"-.!H6%A2>6!%-G1,3#1G<B(;1F/'4/ADE243((7@1-,A39B%?2DA>189DE?<8E5E%DH!>8?0G2=86?9<G,E7-)591G5G!F6:>'A)*+?+E9)>,B-<:%25;A/=628-H;$D$A+=D(<A;%:$03;%2%BG<<E#48&4>120:<$5>!%;$F&97&3C"E>,/&'2;B8@H-!D)H#/A%4@$-A<3&#"&.4F$#+6%'HG2B60?'%&B54&-
@r7498
TAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCNGACATCACGAAGGTGTTTATGTAG
+
F5(@2A9EC0DG"-65#B:88/(H!4)F)7.7:"'!*C;2H1+77;*5.)/,1"!9421$/!0D510":7;(E&CB*#BG4%(3<+8"B<4H?)&G:@GD+E@&CH,7>F*,646$&8"9>=-2H49CED;92>2D?-<%2
@r7499
NACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAA
+
!>)6;7F*4<-,4G=48*E2/<)'!E<FD(1>GF/&76C#53'1:&+3#"2&2!E+>941
@r7500
TCCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGC
+
%/?6"6'F,*<A)1':0!G0!&10;>D4*.2!A%&A9?C,0$92*;>)F0F"CC.*7E)'=AD<B(3*-H%!"E#3"89$-2;B'4/>5;/-)&320A8&#>@G-)+A);!-*(2GD?;=<
@r7501
GTGGNCGNCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACAT
+
G+EG"A<G%F(F>$$".$<F>!,/(7G/15D1?,.<87B%(G=/F(;A&#19'2C6>*?.:A=/#">$'21*D>H,C11AC*AE'!.8--50#!"7:G/AC'07?18F*;==D)!;GG%BC*%=/((1BD!DB*$+E949A1*7-8((2G(
@r7502
GGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAGTGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTGGTCAGA
+
**$)+'*"%*!+)#("+&(!!(%%+*$*%)*!&")%'*((!)#%**%"%#&!(#)"$)(*%&!')*+"#$#&"*'&*&%)*$+%+"*"!'!!""!$#"&*#(%#+&#$)**('+)(#&)&%$)'$$$&$'+*#)"#)$%'+(*!*#++#!&%'&%!!"*+!)"*&(*#%+($#&))%#))"&"%$)$)*++)(+'$!#%*%('%**"*#%!&)(*('"))#&'(!*!("+++$*!'#++&"$""'&$&)!)%'")$'%'")!+(!&)*!(%#'(+"#++)#!#"&(+)"'#*+#*"((&$%+#&"%)&"+&&$'"(!$"(%
@r7503
TATCGNTATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCACCTTTGATTTCTNTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCCTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGGCTTTAGCCAGAATTTCTTTATNGNAATCG
+
+:CDF/+"F4.!8D'C4!+6F=!72!B)%CGC6+3$3DA@:9GCD?!B(AB4(+>6@B$@>$,5!'@C#,@EB4'-$G!F0587>'1A'AB5"?$>$)(C+,AFC/6C,11(%F&*?4%DF2@$+E;GEE-4>%1?#*5CB);#%)@;&/D(?1!F+C9@1%@.;",E%;*2395//*C7;<4,8,-&;59,F5"686:H/+-?)3A,34?2'684(""H5'4HG8+C)$12!C&<)<>&-(055=G*6@<'5=34428936-864.A+.7*A>?>8$D;B082:;%B2A&$:1(
@r7504
AAGGTGTTATCNCGGATGGGAGTAAGCGTATTNCTAAACTGGAAAGCAACGAAGTC
+
1B)H"+F9D",2A49!2$-)2/-9,5<*H5>/DE!B/9$DE/%#)C,@-3?8'4:;
@r7505
TTTNGTCANACTNCNTGNCTNTNTCATNACGNTTNNGTGATGCNAGNGTANNCNAGNGNGACCCNANTAAAAATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGGCGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAA
+
$%%$$)(*%'&'$%&#(*%*"($'"$&!)$#'"!!$$*(*)"&!%#&)%!"!%"%"'!#$"$(*$#'&(('$+"&'$"'!'$%)+%###)!#&*$**$#!)$"+!''++!'("%*'+!''+"!#!#%*)&$#)!$")(%!&$%!"(++#"!$(#!!)!+#*("*"+'"'*#'$($+#"%$'"!!+)%$)!$*($%$&'+(!)+)'(+++"#"&%"!&)"$!*!*+(()$+$)#&*#'#'(""%#+++()"**%(!)%'$*%(%#+&""#%+)$"%'#"('#(++(!#+$)+**((!%!)$""%%!)%%)'$*%($"'#**+")#
@r7506
NATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGCCAAATAATCAATTATGACGCAGGTAGATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGA
+
.DG(>+(*#)749=+<,G>&8692G+F?FF<C81D)'4?);&-2+>/@5'2$E+"31(A3"D;0D=18?'8:HH&+4675;'<*'6=:-%H>8=4=/98-<#=&C*H<3-D-*B9%*5F9;/+-9(;<$97'F8-*'H20=0,;*'H%.?&-11:F+59!E0=2F!0!,&E7?,%C,B!G@@171@0
@r7507
TTCGTGCATCGTNAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAA
+
</)>$8#>0'8D!*4,B61-74E8#<*(26/-31$&(4*96>.(H%"5G(AD,8E+=1F
@r7508
ACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGG
+
-07'B">75G/"@3:D7;%>):D3H-,*/51(#:6E'.B2768%;'/"8<G-1BB/A(G*
@r7509
NCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCNCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGG
+
'BGAH6BF5B.%8CB28;<H.(1H01',699!C>,.42/4G>%E$@<.;4*2)=-=,,.89AB>"(#'6#*,#D/&@7+!:-5"@-4H991#=G8A$D>(-=E**-0:C"*88%/C='
@r7510
NAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTNTCATGATGTTCNGCTGGANATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGG
+
#)F""-89F5B&#0-625+?5/31:*-2;:&@;,D*49=%:&.8=C/AA0:D)0B?269'054579"(C&AG*FEC:E*),(;.<2@&F789>@HD='BBA:HA/26;<E809'C">/7D?;,H9H3*2$)A6?=*>@,4-7G40!?%@:676G>;-CB#9C0$H*@F"3?1>F6G2C;H!>?<B!*>4!B0@FEG553-:?'(#52,.10
@r7511
CANTTACACGGCTCACCTGTGNGATATCCGNNGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAANATCGAAG
+
&(($')+*$+)%*('!$'$!**$&'!%&*#'+*(!**!%*%)#)*%&*%!+%)!&(()&#)$$"$$&&+$&(%)&)$(!'
@r7512
GGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCAT
+
G<!6=6%(;<;")F0$'B@1F$$0%*1>/-4B>B==:-1C=,&F/?4*F<?2;#BF/=5BE<$@5&,960*'H-%;AD-*(*F?F!72F.+FG?7*E/0D.89!2<E.(@97CE%C*:#C%B5<E?G:5:4C>EDD&)8,)0&,(9"D4%-('FD4D4;E?&-;*>9%2!?$/2=68C'7
@r7513
TCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTG
+
<>;A&F-!BE9:&-=66@/=);C*C?)@'70@>@*H4:<.1;19($C)=D83?>A0E-.
@r7514
GAACTGACACAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGNGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACGCAAAACTT
+
;@)C4-2'<=FG!"$G04-!;;8<"A7"06.&(:5B@)$"3:@;'="=E0(DH::B(8E#A&/;3>A/C*<A)7C=9%C$2@"*(E2=0A+7#"8"/?;%A4%:G.F8>(<'>C-'DGF?C&0,-.B!E=8:$+H%:*0-#E23&E(10+"(+E2,(#+$C($H@,34!&>%/,:D@G2=<6,GB;*9G
@r7515
CAGCCGCCACGTCTGCCTCCACCNCGGCCACGAAAGCGTCNGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGANGCAG
+
1="(=8!)59.HC$BA?1*"-;<G3D0+F=AD;$.4,(.D3+8BA;8/E"&%E)A=B.E&/*'@;#8?G>DE4:%/81DD7*&9"$#
@r7516
NCTGGCCTGAATATGTTAATGAGAGAATCGGNATTCCTCAT
+
20!?#3"7>)E"G4+!F1$$0;8>.<F&D68:6G,.G:1&1
@r7517
CCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTANCGCAGATCGGATGATTACGTTCCTTGCGGTAAATCCGACATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGC
+
?4"/A(5<8)-10G0#0/31B>7BEHF<":-5@$A7F/#!@47H36>)H<H5(?F0%*FH54!D1=>-*08$A;HG,4'4:<;.;@C889E-E8H@)01CA=5H&,9E.1E7.A1G$8>/67,>'8;40C?3E+A@;G3E!<4-&!+F<*'%F='ED7D@&@8H7FG@$:7B'8<9'B"*@!13*D<9;
@r7518
ACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCA
+
4<-31E<2H>/?H"&)1+5<E$,1:1F#9&<,F@EE@@>)G:=-;@)HBF
@r7519
TTGGCGACAAGGTNACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCC
+
5FH;9?0<'F>11*D6B4;51=F@5B;&34;8!'/G'>@D77=4+F(*9/,H@&0@DH%:>-D48G0E518?3:0-/'$A>=+$/:>B;
@r7520
GCAGAGANACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGTTA
+
CD+459C4A>(#.@#8G/9B$=9F3%/"=A5C&3H1->@B@>:"8*
@r7521
TGAACTCGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCA
+
,27:C1@&H>+.B-=<4!.8?!!"<3=C":<$F+=%#H-++@$.?0>E.CD:CG1>;B%7BH8-5.1>$?>@?61%!/%?87"248->34:"#707.,8<D
@r7522
CATCAGCTCTGATGNCAATCCACGTGGTGTAATTCCCTNGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGN
+
*+$++&$")+&"!)')&+!)*(&++$&"$"%#+&'&'))$""%%&#+*$&%)+&(+)!'+(+*%!&)(&(+*"$*#+#%)%%)%'"$)'*#%%+!%$""%"(""+
@r7523
ACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAANGCGGCA
+
01EEBF4/)>?//;FE>6!9+>40-922:=@>A&&2"@D:?"#AB="5-":/G+E4?/!&&1D((C/.G1)09!/4-@DE?C'<.E&0,9530532:4H8#9A?)(3<D+/
@r7524
CTCTTCAGGCTTNTGAAGAAGCGTTTCAAGTACTAATNACCCGATAGATAGCCACGGACTTCGTAGCCAT
+
':7'!?C;1)CF4;%D27:D:$+(1@AB$H#96!%6338/7'(H:&&!G!<?%C/D2>C=50>0$"E>/6
@r7525
AAATGACGCGTGANTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTC
+
.5536%?=*C5EFB=1-F.>D(2&/+'"%G@HD#D&#B&&-7*);$58D"G&C@
@r7526
TAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAANGAANAACANTATAGAATATTAAGCT
+
:118HDF!24$)'D2<'*#A@+(7B%&4&A,CD-9"@'GFC<*D#<A+22,(0<$964)8)9<"B;=4
@r7527
ATAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGG
+
-*74B>"H(/@>-.6-=&-0H08G?27-BE:'3$C51H%$22/;17B$%2<9"H'6<D!538!-947D3$%+B(5%.'03>C0E01@'%0:!?:&3BE=7&<8AG;/0@+;&
@r7528
CNGATGCTTCTTCCCGGCACCATGCAACAAACTGCGCNGGTGATGGCA
+
C:6*B;71C$D;&B4*/4B(0'(!#=&2$;FFB4,'DD5'&=@54B$E
@r7529
GCANNACGGCGGTGCCTGGTGCCGCCGCAATGNCCATTGGGGGCCAACCGNGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACCAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAG
+
$'%$&$1A5A/+4!E@"C':"",8.5%$*A3"D)$6F-.!-GH*F1)-;B1"+@.DE()&DF>%>&:F,>0B(!6#:."F"$/&'>4/;E3!*60!1D")CA+:3,+<!A,29913)>;>6/>9/8<,H2>441;*<E/-#H,)0)1
@r7530
CNGNACTNGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACG
+
)!)!#&*#+'+!&+*!)"&+#$+#(%"!"%(()("#$%&&*($%$)((##+(+$#!#)+!(*
@r7531
ANTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATNTCCAGCACATCAGCAAAACGCTATTCACGCA
+
#+$!%"'#(&#"*'("'"!)+*$#*'&%*+!**&+&""$*!&#$'%(+%*#$)&*"%$*&$"!+%#(#'"+'&(&#$%)"!+"$"+#%$)*+!))%*'&('##%+'"!!)&')"""&!)$'#
@r7532
ATTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCGTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTNATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTC
+
":5.H"3%H#15@C;EHF3$1!-?3/,;$&?*1+B:#6C@5>H.070=:07*F)7@(@.+5"&+';"/6&%:&-:*>20/,=0"=@!0#1->@9@((EECB631!+@!"&&:*471.<"(!6D=CF6/A@<6.'-D:H?08:?C;(0.F1AC2
@r7533
GCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCNCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGNACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGC
+
?74G$/!,HE8=,28'"C#@0A$9#@F5/C8.?C9$H7<<)DA5:<?7HC=/6+4@$.FD(!5C3:=3$<A*1'#(GB7#/#<C8E.?&"0%2(=9G>F&"/5-;B?A9#H,=F=D7,:DB7@$A:1H6F17)/D;6@B?*9/:#90.:+1,A7B<+B0+(!/&A+8H$BCE')"0)GA%E@A'928<8D?@64;(%B956(.;A#064>?@!G=3&"H=BC-H?:36#.;)D@8/A(;=@G0@@
@r7534
TTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCNCATGTTTTTTCGAGCGTTCATACACAATGGNCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTC
+
H&*;8)>C*59;G52+.72,:44(#<!'69005;?070+@D.B=C-;H1#7("$C:!/80/G-0@!%D1FG/"+64H69F;EA="A<$E><#CB33H(8:%9%*-EH$$*0E(;)-,6H,";72&B;C#+58A88#7=?C$-<,@:.H%'/3E3>H.>6AG3/8$@"$,1<@.,DD6*9B7-#;6@">#81G
@r7535
TGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTG
+
B(5-B+E-CEGF2.5G)A)G%&'$F3:58+89<<0(;57C>;'?,:<C>()+;;6@9"H9G%63;?A0H,12
@r7536
ATTNANNNCNGAGATCCNCTAGTGATTTTAAACTATTGCTGGCAACATTCTTGAGTCCAATATAAAAGTNTTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGANTCGATAAGTCTA
+
"*!!#"*"(&*''(*"%)$'%)'+)&!%"#)#*$"%(&"+#$%#%"'#'#%+!"&**%"!*!"*&)(&"&#$!!")("++%"'&%$'!)+%!'$#&&!''+*"!##!%)&+#$$*$++$(%"(*#)+)'("&!'&*!(!*""*%#!'($++*&'!!)*!%+'"'!)$#%")#"!)($(%()$%("'+'"(%
@r7537
CTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACNTGTCGGGCCNATCGAGCCATGTCGTCGTCAACGTCCCCCCATTCAAGAACAGCAAGCAGCATTGAGANCTTT
+
+":1.&$'25>@<@B4>%<:BBA(93/+6<+-*#;D,(3:(-1EC-F=GH615()5@AFG/8,H0E*4/1E4++86.3$9H79&%#'+E4(<8H*6#H3C0C!0/<1&170D>>H4'(
@r7538
GGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGG
+
D&>&59;,1E%=+*;7.+$@<!CA!GE.!-0-DB="%(C:49%AH3"
@r7539
AATCTCGATTACGACAAAGAATTTCTGGCTAAAGCCTTGCCCATAAA
+
*D!*5$#,B$#BB>>D1?G6;/$2>G173D7@4F*+.B,)?BE/*';
@r7540
TACAATATACTAACTAACCGNAGTACGTTATTTCATACAACGTTTCTGCGGCAT
+
G58-<HDC5G.+*+A7H;G?<';>$8%A1DH*14;DCF:F"(9&B+E(B&0C.#
@r7541
TGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGCATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCACTTTCTACTCGTGATTTCG
+
*$(+$(#$'#$"(*+"(#$%"!'%$'&(!'+*$))'!+%##")"#$"$"($!$%!!+#())#+'+$#%')#+"+*'%(+#(+&!*+#(##'$%$*&*$))'%")#*
@r7542
CTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATNCA
+
F,+9F*$96#9D-))C24$.;31>!G!D/HD56",@/;1/,5%.91>
@r7543
GCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAAC
+
GF.!9*BE$":B>C+(H;//+*B5$%3.?>-C=:<BD49)?2CCFH7!B<?B;F'7:B;!@,-<$&1+B5,"5.)8%"1*$'8%:BA:B5!+F5?!/5.A$@B46?="='BH!!=F("':>?2CG/0*0/%*253/,*6=:-,.:7-!;!&E#@.!,G1$BF30+A@-37C3169@/*-C@/C='FD-<H558
@r7544
ATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTATAGATTTATCGCACTTGCTCANATGCTGCATTGATACATATTT
+
-0E%/C%76$*B@="/0;1G791@'&3:;(60>0C;%88/05G$01EBC.0?A#'*G3E4B#*>/0=,(8/"(-=5%+8.G;?'FE"9G%*&<7(%4@5:4
@r7545
CCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGATTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGNCGATGCAGCCTGTCC
+
ED%-E=1&.@6#E:C$G2HDH*/8A?-?.7.0?D+*#+-!F-DD.C&14+A;$5.087G/6#&D*0.6'56>$!%1(69:8<??B3?*8ACE;/9,(H/>%=A/'6A7,H1B
@r7546
TAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGCTTGTCATAC
+
@=<!-(4>37#?>;*"-CD=GAG@:;35;.,"-8913*8+-F5)E<C@$/E)'G*=7
@r7547
AAAACATATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAA
+
.F<B($;F1"D'4.(B'$844;@<="+F:?..&A/@=8FC35G(6"'6
@r7548
GCATTGCAGGCGGCGAACGAGGCCGCAACGNAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACATGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAG
+
E"!*'$8<0):;3@F;E:!0-/'G'HGH**4!&@#)E@9=>;EH9#35@AG,>7/F"$(AAF1A%%'GCC'G#4H(HG/C"G.@H'DECF/4195<)8*A<#.&E,H=F#E#-)?3=/)$<;5C63-:=BBA*(+=D%A6GA5H9'(.7:9D###+1D5,@;*'8
@r7549
NAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTNGAGTCGTTTCTGGAAGAGCAGGGGGCTGGAA
+
%FAB(>34#<$0<4(>@0-82*BF=;+%%H73$?%55!1;7&G?E<,>/=+=2.#),B",!-:FD1'29G"?B4<9A,D$&
@r7550
ACAGNANGNCNNCNACNANNGAATNGNTNGCTGCNTNNCNCNGACGNGCGATAATGCCNTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGTACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGGGGTCGGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTG
+
*%!(#"&$"&!($*'$'&)#$%'$"$"(%*'##*"$"'!*&!*)(''++*$&+&&+**&$*&!''(!()&)''""#&+(%#)$!##&$&&+)+%')!"$&%)#)(#%()"'$$$*&#&($!&#%!+''&!+'##&*")$%#%)$$$%$"#!()+)''+()(+%(!*+*%"#%#+#(#+&#)%'(%)"%))$+*#)''"((&"+"%()&'#%"'*#(*&"$
@r7551
NAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCAGCCCCCCATGCTGCA
+
!2;62*H9,,C35":%<@@A=D9@:!?&;#89(,>-!$H1">+@7H*F98=B0
@r7552
NGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCA
+
!1%BG'?B0H4AAH7@#'(@<A$$A:3A.A</3B.-,B"&%&E5C><B-3GG&+D<&<D2/;C87F3:'.7,(/C
@r7553
TATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTNCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACANCACGTGGATTGGCATCAAAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAA
+
(;E;G;:17-'>E/E'5;@$?23AD#CD805E=7%$B<8G#F<*6H95@H;+/.!/=0G)2E6"<*BHCD#(&A0";1@&DF"('!A3"'73:"C<.A;B6/&AA--+?=BCE*=0->F13!AA:1E,$*7$64?(+5(++.3,-:6H7#>0.@+%*C>>,,,H6&?.H==*;5F..)A'(8%A;D8'#5.>1<!21$D,3/H"!B=&.5DG31-0F/;D.H/59,F)"?.;0A-H/90,94*0&'0EA$.2#F=@$G%<</&C>6#(;,@?.)C:4494=77)<;)E5F2*A.H2%)"96A@/>)*H
@r7554
CTGCCATCACCCNGGCAGTTTGTTGNATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGNCTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGTAATCAAACGCCCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCG
+
8)2$/&%'6*A--$></<0(BGC3*9?5/4",3:=&A?-EE#EC+>*'5CEDF?H$$+F9H)B*9)A7A)%<;>EH)*%.;.&=($H>#.7$G-&F$!$1,1*'F*+)A46:H97-E1--0>(%=G5$@<36"G)5B54');142D+''-B?*+.A78"=.>+"B9FCC6'=")!G&<F*F$AA',5#5"@-E>C$=D4+870:@+)9!2$%39,*?.DG9'C=G-&974A5(,4#181863D,0.3-:(25?89/A+.&CH8-
@r7555
TGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGNAGGTAAAGCGCAGACGGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGAT
+
A;+5$4,C4'6>63@23;3E6!:7,6?#C(7?=7G#5(%6A0D(07;F%HE;%:%;:3GB;DE1C6(&C21(0E$3;7CG!>#118?0:D)+2!,$.@;<7CB60@'G4A!H!84FG-F9?7("
@r7556
CCGGCTGACCAGCGTGCCGGACACCGGCAGNACGGCGATGCC
+
)!+'&&+%$+%(+&!"%+)++#)')"''!&'%("+(('$"#%
@r7557
GCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGC
+
-=)4-.5G+,.@>8;,@#%3/FDD6?(&<+,%+>F.=,A/0$F9/E!%4G?**(75?(&'4-)7&=<+6&A.(/B>7'?1;>%A)/-F.**C&!02A,;8G61G/&7*,'2*7
@r7558
CATGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGTCTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCG
+
'?E2C-49/-"G=G,7D8.>?3)C/."D<B7=B"-+%D"7HA#-93GE1;2H4)=.A2$H5,AB:B2'@"4,1253HA$G8+=&B==23D4#;D&;D%-!2C<1B$(B3?+H08)FD!,<8.<=!G>D7?#(HE=B<B!0276>'2H;%>'=>87/G'
@r7559
CCAGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACNGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTGTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGNCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAANACACTGGCANATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGANGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTNTGACCTGAAAAAATATATTGCAGAGCTGGCNGTGCAGACCGGCAT
+
**!)&&%'+!))*(&&+#((&!"&*!""((*$##!'!*($$"#%*'$(!#!*!')&"(+*!!$&'##'!"((#("("#'*)&&+(!'(*+#%$(&$((%%#$!!#)*&%("+%!&"!#*#+#()#*''$&&!%*)!+%+"&%""+%)$+#+*%#$("++)!#'')$+%(((+$)**#$&*$$*#*!''#&""'#&&((++!#+)$*&!)!%%)*&()!$&!&)'#*!'"&&)&!(+#(*%*)##"!%(%*&*(&+%(+%#(!"&&'%+%+*)#*!&%*'('!%)#&#(&"%$("*!"$&!!+%%!")!%%%+!$%(#(($**)*('!#'!!"$)$'(#!&*)$**+(*)"&*$$#*$+&**%+'+*%"*#)+&&#&)%(#!&&%*&)"*)"'$+(($&%!&#)!!)'''+'$("*&)'($)(!*)"+*'))(+*&&**&!%+(*!'&(($+%$'(("&&+'%+")*$*$&&#!*)$#*!*(+($+&)")!)'*"
@r7560
CTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGNATGATGGA
+
&5#%)*.G<*@F*A3&0C1F:;#$18'D(9G-<?8=(#;CHB+497@!A)4F?+#F<:%(B*>7%C&;"
@r7561
TCAATCATCATTTGCTCATGGTTTCCACGNACAGCTCTGAACCAGGGGAATGTGATTAANTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCNCCCACCGAGATAAGCAGGTCTNTTTTGTTGTCGNATCCAATCGTATCCAGTTTGTTCATCAGG
+
?5'%2?4H@*+7/'%3*<!?@4??H7;EA%+&1B?/%)2<<0B:H%/<!+8!#9&B%/G1,1)+2488.25867$(2:0G;?"4C7B86@?!'90GH2!37-#/4!;#5-=$G2=B(>EC@73"0(=0/#4<8'AH4.*B+$!H2F5,A>$)A#(>)9!@<)69$
@r7562
TGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGNGGTGTTAAGGACGCTTTCATTT
+
*+#&#(*()$*'(+!'$+*&%%*$'!!&"++(")("%+(&)+"#*'"#'##&$%"#*!&$$!)"&)'&++''$*"+'(""%'&#"'*&+)"
@r7563
CATTTCTGATCCTCTTCAAAAGGCCACCTGTTACGGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGT
+
#8&?9CAH"#0,'8;:E>4D3(*C396C7")679H>#,H8>!2?(,D8@EDB@D4**(9>C7<-#:>+9?+::)*26F;5?@F2:;'/>!:,%->0*66C9=.)*&45,9')E8/D1@290&E-'98(B$;7@0F@.%!G*/A>%H+74GD;:4?%H#1-,F7"HE:'&3A.&?!@<+4;$:DC&!-H
@r7564
NNNNGNCCTNCAGNAGGCGAGGNAGNNNGGNNNTNNCGGANNNACNTATTNNCGACNGGNCCNTANNNTGNTGNGCANCTGCNGGCNNTTTCNGNTTANGGTTNNNGTNNNTCNNNGATAGGGGANCNTNCGNNNNNTCNCNNNNAANNNGNNCANNGCNCCNGGNTGNNNC
+
"!$"$$"$#""#$"#$##!!##!"!#!"#$"!$!!#$$"$#!"#"$!!""$!!"$#!#!!$""!!"$!#$!"#$#$#"##$#"$!#!$#$$$!#"$"##$##""#!!$"#!"#"!$$"$$"#!##"""#!"!#$""!"$#$"$!"""#"#$"#"#!###$"$$$$""$!""#
@r7565
NNGNNANAGNNNCNCNTNNAGNCACNTNTACNNGCNNNNNNTNANATNTTGNGATNGC
+
!!#""!##!"$!"!"#"$##!!#"#!!$#"!$#!#$"!!"!!"!!$$!$"$"#!$!"$
@r7566
NGGGTTTTAATNATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGN
+
('"(+!#!)$(+$*"&$*)(!###$!(&%&"+++$!"!'$*+'+*%#$()"#(#
@r7567
GGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTACAGCATGGGGGGCAGCCATNGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGNTGCTCGG
+
:@A6;"<$@+&:"!08.01:>*C:10$G,422;"")9FB<,<DH3$)B/0?3A#.270D:)1<66F?E2:#,F:D.E&D1F:F0C$<9C?8"#.DE>?.!B)/"58.(>C8*)@.E0)2-'H-(F)$87<@4D<1A3F53&1B<#4#;&#!1(9-$-6;)7
@r7568
NATCACCTCTTCAGAAGTTCACAACGTGATAGCNAAACCCCGCTCCGGAAAGA
+
(&+#"*&!(%)*#"&&(!*!())+&&)!$&#$$%%&*#!&#)'+%#)!*&&)%
@r7569
AGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCAC
+
C-:>%?D)#&?D(329E%.1C<$(.0E63<.$%-8*4B0$";21&:==>
@r7570
CCNTGTGCGTGCTGGATGTNCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGAT
+
%(!(&$"*%$"(#'*%(*(+&'!!#%!+#&"(!)!#"*+&%+!"'&!)**'!*'!#%+$%%!)")!(+"#+((&!!!"''
@r7571
TGCGAATGCCAGCGTCAGACATCATATGCAGATNCTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGNTACTAACGGGTCTNGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACC
+
/);9=>"987.'AF?04*?/F9133GC.4G*4;&B?*&5A#GD"<6:=55/$35/)<<9-&&:G&6+!&;::7@8".!/6"3,+&+B0??($(?2'@/F8,%91G90@(:%GH1$9>D#-5F;7#%-53(%BAG9C'.-4@G0=(E%8(47
@r7572
TACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCNGC
+
.;*)*<E<H79?>11@.%@G4<<.EB;/E(@;:/8665;7=%$)#8
@r7573
AAACCAGNNCTANNACNTCTGGATTNTATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGNTTTTTCTTGCGTGTA
+
!)(*&*!!#%'*#&!#!%#(*'&'$(%+&"+'"!!!+*++!(+*+("+(&%)&#+#)*#%)$*+&#'&+)&!+&###*#(%#&)+&+**$(&')%%(!#+()$$*+%#"'"%%++&$**%*+
@r7574
NAANTCGACCNGACAGAGGTCGGTGGANAACGTTATTTTTNCTGTAATGGGCAGAACGAAAAAGGNGAGCAGGTCACCTGGCAGGGGCGACAGTATCAGCCGTAT
+
!%%)+#&&#!$!!')#('+()!'"$&+%("+''#+&)'%"+#+%"''$"#(!(&%$(#)(+%&"$)"&'#++((&)("+'''"$*(++#+*)#$&((&!*&*!&)
@r7575
NTNTANNGNTNNGNTTANCNANNNGAAANCGCCCNNAGNGNGNAANNGAAAGTNNTNANCTGGNNACCANNCNAGNNN
+
!$!$$"!"!$$#!"$!#"$#$#"#$$#$##!##$#!"###"""$#$""$"$#""$!"!""!$!!#$#$$"#"#$$#"$
@r7576
GGGGCGATCGTGAGGCTAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTNTGGTCAAATTATATAGTTGGCAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCNATGGCGATAGTGGGTATNATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCNGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAANAGAA
+
F$'?"A!8-4#,G*:*%)!%4(C6-,&&)0?'0?),CC.=B6<@,=4%"(A(%1;.+$/"8*.(2-%9:@BD9;E2;("!<670E7H(.&D??,'&%2B"6A+C981+<EC*4*$<;*A9?4B*.E7413A6G6'A;=?E7!&>FH?@B',4E4->%C+E#&A;$4F8'GGF!<?-1,,/::$+(8'3=@!E3;-A8">5*%9?5&G%9><1*8D*@F@-,+1E?CA74$.?"+,8HB!#&B(3;+?,4'$@,GH3G1D"';7#1:2F3;H76()AD>;9.!6:,-+&).A>=:@#787%1,,&7#,43$*F2'2E@1*9%6),!,#$%F@3E6)/!+"-2&,=5E(?#(F$&7(95>)/+8A.8F4><<"BE,8A9$B
@r7577
TGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCAAAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGG
+
@(1H6BAF;CG')781-%B,F6H!71,G2-.:E.8A,%6$,CA5-7/H4F:(3=)7/%<D)4<1+C:8E*+C$-B=+0&,)6F)$-$>+=C0G%"%H/)4D<?>%/22);,H<DF52
@r7578
CATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTC
+
*+'*%")#&'*+!&)''!+"&!$*%)*!&($(%!"&'"&!(!&*(!+)'#'+%$")%'#"'%&$&)$&)&''*##&'+(#***)"%*!$##'$)+$"&#'(""%
@r7579
CTTCCAGCTTTCTGCATCCAGCCAGCGGTCATGCCATTCAACCTGACGNGAGACGTCACCT
+
400@/A-8"(;5$/$G"31>H,#;#CBG'A2"!0EA'1CAG>3F#@(F7G8%;AH3*"0:7
@r7580
ATGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTNGTACTGTCCACGCCGACGGAAACGGATGGCACTGTTTTTCCGGGACGTATCATGCTGGCCAACAGCTGCACCTGGACCNATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATC
+
!$+%))!$$'(&!'#!%&%)#'("%"$&*!#'*!)#+*'"++%$"'%"#()!!+*!***!!!')''""!$')#$%*"*)"%)()"'&##&+!"$+)"&(!)&&'+$+))'!*&"*&#')*"&+%$%$%#$&**%&%$&$#(!(#&$")!%&#'$"%&&&(+$)+&+&*'''!%()%!&))##&(+*++&!!('"+*"#!
@r7581
CAAATAAGGGTGTTGCGCNGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACAT
+
E8>8A<+9**AE'3+CF%=#4>,&(8:A&8F7DA<04C;D0=36,:>">/3AG(?/C"C4B(7DBC5)?0!2C?'89+B-<D"6$-'7.2*C)F
@r7582
NNTAANCGCCNCGCTTNGNACNGANTNAATGTNTANGCCCTAATAGCTCCGCAAATTCGCNTACACGCATCCTGCGGGTTGACTGGCCTATTACCACA
+
$*#%)'#&)%$&%$*"!##)%#'$!##$#(%$"*"!(+"*$)&!)%#"+'"!"("**#$&%+!!)")#&*!)'(+"*#+!''("!(')%'#"$!"&#(
@r7583
CGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCACTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCNCGTTGAAGCATACGG
+
(G(<3<-$:H)C$F,H<$C&;1FH*?B@>B58&'9.H72G""3>):+&@4>'*$9H4/75@;$.&)?:(C.!75:!3'HC5H/(.AEB=%'&3?2BFH2@78B>7=)(B9F3'7A=:1?'GB;7.B?B7F2024#':.?,9HCDG'B'%%?7,:,(&+)EE34!2*35G?:,B"B?FF5<00:$0@=4,&BHE@(73>(0,+$84-47"<
@r7584
NATTGGTNNNGGTNNCCNTCTCGNNNNAGCNGANANNGNGNANNNTGG
+
!#$$!"#!""###$$$$!$$#$$$"!#""!$#"!##"!"$""##!##"
@r7585
CCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATG
+
59+#.!8!?4>=##4?3"+=)1GF>=15.=.E,.%,+?%H@
@r7586
GGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCNGCACTAGNACCAAAGGAAACCATCACCCATCATTTCTTC
+
@G.;*FEF,<>%*@C%D:*G'9HD0-8#0?=D$A3+5C16%H-E<=BC3"E6D3F0!H9610=%6E"?:1C:D$'B%74+<.>3B6!6",8/,/:+<*0*5A.87'-@;D1F9.9#=29-.)7@GH#$2#472;;3;
@r7587
NNTNAATTCNCNGNNNNGNGNTNGNACNTNTNNTCANNNNNGNNNNNNNAGNTNAG
+
!#!"$#$!!"#!#"$!$$$!!#$$!$"!$!#$$$!$!"$"!!!"$$$!#"""##$#
@r7588
ANGNTTNCNNGCNNANNCNNANAAGTCGCTNNGNNCCNNNNCATACTTNNTGNCNG
+
!$$#"$$$"$#!"##!!"!""!#"$"""#$#$!!#$""!#"#$"#$$$"!!#!"$"
@r7589
AAATGACTGANACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATANTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTC
+
;@E>@B38*$=2G$A4.E":$!3/8:G.$(2%3G%;=B*/)B8=E"G&79"#?E>FG8,":A$G<'.="A="20,+8,!#).(G5D$"5DGC90D"@0G'F84B434>E8"193A<D*-"-49<>F>.65><;*G,0+5':
@r7590
TTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCNCCATTAAGCAGCCAGTGATTAACGTTTNCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAA
+
&@3)=8A"<81F/,+EH%@&CH?@0=4.!3EG7#"'7&94@D76CE:<"2/;%A5@#9E/@;#G/(HA%06"A#61BH/8G5($=/@0DF=:*&$348D8744,(CD-;>8<:&#0#8*#C'9>D6>H//E>
@r7591
CTGNTGCNGGNTNTTNATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGA
+
$'"""((''(!(!'")*+)%)&!!+#'"*&*+%!)*&'(''(%$%)%("*$(*(#)"$+"%+**"##
@r7592
NNNTNTGATGNCACANATGACTAACNNGTGTTGNTNGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGANAACAGGAGTCTTCCC
+
!)!#")(!$'%&!"'&"$!(#"$$&$!%&%%)%&$!$%+)&*#%&!&'+*+#+'#%%#+'$+$((###!%$")"(+(#+"'*%"'$%!**#!+)&!)(%
@r7593
ATGGCTCAGGTNGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTCACA
+
@1A9';,#)F93<G;FH"&.5'2<*/)@4GD.//!$8)EG(?:,:?6==FG)<6GA,74%G5=)81%8AE-A@?680<29$/8!2.'%
@r7594
TATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATA
+
*":%(53D?7,/>?#A9@B%,C</D,C59E(:%'GE5=4A:<6#F#B,4!=E(
@r7595
TAGTNGANCTCCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCNGGCATCCCACTGAGCATACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTTCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCG
+
''$%#"'!&!$&*+%%'"*"&!%*%+'+*))#')++&"$))")!'(*!&!*"(*%!$"++)#)%&&+(&+"*!"(!&'!+)*)'$')##(&!"$'+((""+*%($*&(+)"))"#*#'""("#(+#&!%!+%#$+)!+((!#%!!)!'+!+$+%$&'"$&)"&&#$!&!!)"##!%#%('*+)!')%)(+&&'%('!$'&$#'+$%+&%"'")+&&$(("*('(*$'#!&('*"%'$'&(+$#&!)'!+"+('++&%+("
@r7596
ACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCANAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCAT
+
<!/1+=.8A99</.8"*/07,<C#$>/1'0@D:$-?4)'=A(8G>,G8C):*0(=@6"<4#+:=-6A!B#"B)<7ECB701C+C@B@D63F+H'=H*>/-?A;;1;@6.4%*&(.;)C'?:<1=%+=<("34@@*3(%A-$!&;DG:0-A)HH8"'6F4?+1C:/9+:#,46?=E;9EA"H3D6F!C?((
@r7597
GAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGAT
+
8'C)#8!%9E2.C6??0A58;8:BA&!22-6;B&E=H-7$1(23"->$)404$GGE=E7.(1E5?39<4B)E&F%"A$GH%#0:%0$<!??(E0)0>?-$$:A(EC)$?A-=*46'A(3,16A&?"%*=@@@5.1'@:9=6,G#-H8B(?9"@,3"*#EAD"+17C,E4$//=)4#/G.F4EGF"1FC,@=9'AF2'$'1>#$;3E@/<%C9?B'+7&$H+BEG%!,!1+/:5!:B;D5$4#
@r7598
AAGAACAATCTGCTGATGATCCCTCCGTGGATCNGATTCGTGTAAAAAATATGCTTAATAG
+
7&F;<03G?-:',&.23B8'16B60*?)95F"G=1@B8.C>'9/.18-A:@D&D;&!H'0:
@r7599
AAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAAT
+
>+?B59=:)2#<;#,H22E29(?#$&,F%F?6)8:G8:</5%)9+?HF4<6%5B9G?;A!"$6(*7G3067&@"A>C>#6$3@H>?2,B!:3E4?40=,50<
@r7600
GGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTTCAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCCCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCNGAAAAAC
+
H%3.<F64<B'&B;A6E<&0=96>A$#E+:H((>8((G;4A?1!,6;+-!<'?05560"3AF(5'%662+H4"6D,0#--C.EFC5-9E:<(E:.8(&5*B'.>046>.E;%H1D$=E=14(=/-1?'D1;+"'G;';E&58-F6*)HDB/74$E49D%B/AG#:?%DC88A6=C<3<&A$D2.-2G;12E*"A2>()73$59<C!?#.1)+B)0=(2*2,>9?33:@=8>:1#F)C"71,44&+$1$'G$%15,)#
@r7601
NAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACNGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACG
+
!)@C!#B-45&:/H,')F9".%;8+@G!95G:1=;,<8G5G'?:3?6:FA./+=-:%G:.4&23E4*5G5H/1<AE21?"$/6%&#F>2D4'73(C6E40D)-45!:@-GE19==$15+:26>0A##=<9H7$3'#,9!'!#)(&6C46AF9G8?;/
@r7602
NCNNNNANCTTTGCACTGGATTGCGTGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACAAAATTAGCGCAAGAA
+
"*$%!"'"+(+"#)!$"*!$('*!+$%&$+"!)#&)*%($(%*+%%$*$*(##"'')(#)#%#("$#++'!&$)*(%)&#&$
@r7603
TGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGNCTTACGGATATCACCANGATCAATCATAG
+
C:A#EF#0F"G<F8<;A@@"1:D(6C">+2'?2HA)&-*-C)!:G!D<"F5<AD3A6"2,$9/;5,192E9@4C4;B1#+")?(;
@r7604
CTAAGAAATGTGAGGACGCTATTCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTNGACTGGTCGCGTCTGCCAAAA
+
@*@2;;&D2+%/=$%7)@(&8AG?D24#;$C/77"$A70D?>1A#9EC&E>3?:7>B97?2"-"84+,%8DA&B5";"<A'1,E<=A'9+>FD$-2,-67+31D4B#7%<E<=61#*;4/4!&7>@HF;0+,59A/6..'30,
@r7605
TNTCGACNCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTC
+
&$8C7//1#0,!>>98:&9:88C$-BB4B.5"#+#H59,97-/H$+B''D%0$-7"7.'891)#C'>
@r7606
CTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGNGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAG
+
=*-4><C,'G&>;C>3.**4D(>DE3-B$D)=';9:06>@%"<5.=5BD+!2*/E99E:?*A6D)7("29//-#.E2%/>$F60/=%27>93$?3?)1-7F=+%9B,
@r7607
CAGAGCTGCGTAAGCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTGGAACCCGCCTATGCGCGGGTTTTNTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATT
+
B,,0028284783.:>G),;14$:14>;B-=;$?*?:$G>1E/:E9<-<$$"7.'@.G3HB%4C$6>>*@65H(&7B%9%D5!!H3("&:?B&:9C'DDC&?!>HG,:@'E.D?&GE7?9*(8>DA3>%<*C;<='43*<%::)C165@#=7C8@#6/)H(<1?(?5;&<H$'@+>';
@r7608
CTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGNAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGNAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACT
+
%1,A)'=F*41E4A@;A1E?)D,-?*0&G%%>*<;(C<>A1*%(%3(3FAE,)+8A>4C/1#*E"*H70DB54)4H@*16)&"<).E$>(';D*-#1;A1/%B.';C@,@E"A5"(?0E%0+F+$>?:F%2?;>$"F4,>&6A?G/5')4,G4H&BA='E*<4:G=')*9%"&'%$%6'&?:ED89-,3?FG'A<**+0-7*A573EH.H(912:F9@(:
@r7609
CCAATACCCGTTTCATCGCGGGACTCTGGCGACACTCCTTAAAAACCAGGT
+
%>+#G0(8#8D#8>+#*2@(1708<8@7A/5G/G<23,9=6/#(+@BC474
@r7610
GAAGTAAAGANCGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGAT
+
(+6.,4.4:B3F*&"?8!C#%./--AB+.6#G73#5"*A,%+A4$(3*H=<@<"!%;3??=D(6+%?+?G-//'3'D2H/D"3-;
@r7611
GTTGATATTTCTAAAGTCGGTTTTNTTTCTTCGNTTTCTCTAACTATTTTCC
+
?-)2G8>0HF/G*<3=$G-/#<)F>++/:'=5=0DG=2>>?4F?458@G?67
@r7612
GTACCACCGGACCACCGACTGTGAGCNACTCCGGCCATGGCGTACGCACTGACCTTCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAAT
+
(#%$#$)(*+""&(*&)#&&&*&)())!+)(#$$"%&&#+$"'$$$%!*""$**$*%"))$))'')&%$"%*)&$&!&!&#+!#!&"#&%++##')*%$!()"&%%#'*%+$!)&'($*)++'*!+($#(*#"$)!!#*'(""(&)+#$*&*"'%#$%%%&$!+%+'*'!+%)*!)'++"##)%!!')#$#'*$$(+('$("#!&%#"%)!%%%%#'"+((&$*)!!(&&++"#*#$))'!)$#*!%!("#&#%#%!%$*%#)#")**!""')#&+%"'+*&
@r7613
CCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGT
+
A7,$)(618=69)F:H-E@/1&(30"28,D8=5G,F=E97(!&=:#-A9F$+@*!)?)4,G;3+*.<7&:F&,;<1
@r7614
TGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAG
+
-&5*$G8,-<9"2=;#*+-#.A'BG<!:,%(3$--B4:!H05
@r7615
CNCCNCNAGNANNNATNACNATTANGNNCGGGTTTGCANNNGTTN
+
$$#!!"!$#!#$#""#!####"!"$$#$$$$$#$#$###$"!"$!
@r7616
TACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCNTCGTCAACGACGTTCTCATGGTTCATCGCGGA
+
2-26=-:<*;40)=20:$137#?)>>D!%.@/$6%'/-0<29!E8%4,7+D&%#@:1D/$D9&!)5D-?%F?)0E&$-"9!9%&F=C;;8-B78B>D*#31;3*-9@3362867&##@3C971'B5
@r7617
TTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAANAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCA
+
(G'=24960A@.87+<,%4B5%,;AAEB""8#4=!AB0?0"6C<6+>>B!(&>CFCGB&A7=6("A',,"(/;%580F8>7'D9)*H584-F=&HD5B%49,@@10'5?"A,>.7;B%<2-?F@$'%1$(/"85=1A@>-.!'H@>*<*EF.@<B./=5>-4*/H
@r7618
AAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTT
+
=22C1=>3D-!;1<("13=89@-<H.">-3(F,"%9>7</B8@"!H/ED1H9;&%!5"*1,F/4DCE"=-+$E+A-C"5)3.547512"!9E%."7<;1;*C-??B'<40
@r7619
CGGNGAACAATCCCCGNTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAANTTCGCCGCAGCGGCCTGAATGGCTGTACCGCNTGACGCGGATGCGNCGCCACCAACAGCCCCGCCAATGGCG
+
#)*$*+!!!#%"+"*""&&(!+)"!!#)#%*'&)!"(#("!"&$$!#*%&"!$#$""*%'#)%&'+)%%%+()#($&"%!(('!()&!$#&'+#'!*('*!"+#**'**&"%#!'()"'&$*')$$#+$(+$%*%%"!!)&
@r7620
ACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTA
+
G,<(?&66/D(D$<6&@4!+6#(&"8?EC>06C.4B3GF9'6;DD<%3.8)!$5,7$'@8,@*C/BA#;"@3,%6"B&'0'"F9)G789,5A-;;GGFFB6%'2</9)&=F-<H",&H$B8<G;#),25%/DD3&DB
@r7621
NCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGNTTGAAACCAGCACGCGTTATCTTGGTANGGCGCTG
+
+'###(!"(*$#%'('$)%#("+$)&%"#(&!(#!)%+##)!#!%$%"'%#$#$*!"+$##*%(&%')("(!!!&)***+'"''')**(!)#&
@r7622
CTCCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATC
+
*""6)A7<;B/$F7A'.0$/3%D6**;A7.:*((9E6?4:FHC6.%%%'-&"F0#E
@r7623
TCANAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTT
+
8GG;,<9-3C.5#3*A0>2'7C+).,-69=G%A)4C-+2@H(<0EAF,2/"3<27*13,F"B"AFF>1,H3)%!(E:2;(1?<?2A/@@B>+8"-=6=6$1=%07?2@C$0$0:05:5(19)"*$>:&$A-7B<E!)=$$*?0%F9'A,?%4?%1G@*"%38ADE/,:G1H#@'ECCG
@r7624
TCTGCATGGCAGTAATTGCCGCGTTCNCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGA
+
*+#'%($%$&+&('(#**((*&'++"'%*&!(#)%+#$**#(%(*+%('"*)#"('&*)%()*&"$&)+!*!"+%!+%$++$$*'($++("$#)&)+(&#&)#+"!"&!!%%&)+&%&((
@r7625
CNNCCCNGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTNTCACGTCGGTGGCAGCGGAT
+
'""#%&%+$%"+&$#!(!#$*$*"%&&&%$#!%&%&"'$+#!)"'$+!'&$!*(%(%"$**)''$)(&)*')*#)(*#('*$(!)!*$$#!%%**)'$"&+*"&$)$))*#+!'!*%$##('&"&***)#)&(#*&($&&'*($"%&%("'!*'##(+"'&#!"#%'###&(+
@r7626
TAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAANGAAACN
+
!8);!)914&0:6)H)>%!01=64.9472H1-/F#>!!@2G<)B*,=C.@B)<,C
@r7627
CAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGNCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGNGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGG
+
B1;BCAE@FG.>($7D)9++1H5/B(=>4!>7,5++B8694/:B<=50=4H!D-'%#54,53,=*&HB;E20=6A77.46$*9G-8"3H$,GB055+82;6&;#,:DF@)59+'9%$@*/64863G'='&"$0A,8=GCH4E+:C/HF;-,#342((:@*:&=>*D"57!#*7=5108B2D$FA=>+=:"=2D'B3:@%%@A8/>'+E:7$'&F548=49%6$"*5>B6+
@r7628
TCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGAT
+
DB8A/-0((E>E7HGA9()G78*.?85!G=54(*=@<@$C.*>G#$E'!<5""1*#8>8"C7+41=53H29
@r7629
GCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCNAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAANC
+
0.98!7DH?F%@0$($>76%5%07>#525/DD==EH%&39"@"/.9$:8+-BB6,&6H%7=($)EB!:78)BC%&!06!?+$HA4?5>):,%;>:D*HG4$<5.H1A16DB7?&H,.5BAE:&9$:
@r7630
AACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCG
+
4$/.B@,*)%&&B2/;0(/HDB(<#A(7"86$@&")/*410$8!#96+2,,0%EE+B<H6
@r7631
AATATTTCTTTAAAAATGGCNACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCC
+
:+8H85&29?,1:E49)5@2"H>;0(<3"-2*E#'E8<9<&AG9D4>:9&GEC#E1<9&#@.069@B?G@)468032B'9'#;D5<<!-C3@>4=1:,$7&'.+;!2
@r7632
NNAATTTTATTAAAANAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTNGTAGTATTGAACTTATCGGGGCATCGTATTGTAGTGTTCCATATTTAGCTTTCTGCTTCCTTTTGGAN
+
!'('+)!&$!)*"#&&!*"'&##&+"*)(+*!)')+%(!!()$$$*($*)'&$)"&&)%)+!'("#!#!'$!&&!()+)**)#")###**&++')&*%!'*(#&!#+$&+%#(&%%##!"!!"!+$**&*$"&("&'!'&$"(%(+%(!*(&#%%#&+"$!($(
@r7633
GACGTTTACTGTTCAAAACAAACCGGCAGCTGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTG
+
$+()""$%!("(+$!#$)+!(&+!$""!&$!$$+#%+'!#!(#'%$!%('&(%$!!!$)#")*(+%!()##(%"
@r7634
CTTCTTCAGGGCTTNATTTTTAAGAGCGTCACCTTCATGGTGNTCAGTGCGT
+
:(%>/%7#H/.43?$*$B>;)98>G<&?(GFG6('G@.%B9%G.H+45+/89
@r7635
CAANCCCCNTACTGTTTGCAGGCAGACCGGTATNAGGCGGAATATATGCGTCACCTTCACCAAT
+
$)$!$#&#$()))*)+""*$&#)#+$#!(*+%')$(%(%""*+)('*(#&!**"($'$$&%("!
@r7636
NCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAA
+
+"="#"C-:B$4?;3")8*54-=)8@D%-!<4AA<(+$@7*0(/
@r7637
TAATCTATGGCAGAATGTATAACTGCTGNAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGANGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACT
+
D5!:2&.==15C#;=,63'28&?!A1,A"6(G-:!8"G-F.-BE>D(8G/2/-?F5/#6D0%D;;@/C;58@G4C8;;!@6=>F9%'%4HD2?/H<5(.78,"2&G-;7,:=-$E3#B*2)7.5G#;-?/*2&@E.!=$B5G'G)+&%%9%
@r7638
AATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTNTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAATACAAAC
+
@='"%C%5H,<"*@#%?;-0F<;!6#.?6H"F1C(/BD"0-)G61$E?#25"-@H>;3E7G<D,=C@=&*.9'&CD(#0%>D1>4<6-4#:(@?921D0/+>$65>"C#6;E<E)%%5B7'#C'0F96?5*;<GH.5
@r7639
ATCTGCCTTGATCGCCTTNCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGC
+
(%>)A$0<B$8<8AB35D5"82>EA7F<@/+10&6/*39/AC4E)H-+#>/A4D/<G"=30CAF+E4'!%B)C"-?$H5'=F51HG<57+H!G@,'>A".04CC$'&%,<?*?!&A932"3%F5#62C*.:+-0.!CC6*7>8
@r7640
CAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGC
+
/&H=*.+;A;!H8E<;$%5+G3#>&&B,%+0++*$1*6;@*=1*=.:9&A6$'A=+
@r7641
TGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCC
+
D4#A8G8/-+?D,@=/@A5?"*?@%=B6/!93#D-8)-9=;.$HH"AG9$D/!5%F'G#GD>'HDHB3E
@r7642
GTTCCGGATTGCCGCACCGGCAGCACGGTCGAGGATTGAGCTGANGCCGGGCTANTTTCAGATAACCGCCACGCCGCAT
+
+CC8C&)%<#?HF",/3=*<$)6*GG/=EE1:1+F.1/2@2CG?:="DA?)>E"//0<9=5,0+B>-C#9"*:=D'5F:
@r7643
GGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCAT
+
!?A.;CAA'1>4<&A.?##B1E/30F#A7"CD+3D3B-(2!-3A/;E).>EB?%%@B$'20-6F'-"253-B,G/2GD"#:)H9$%@267)1
@r7644
CGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCCACAACCCTGAACGACCAGGCG
+
3C7>5:@6?<26&-!)(D:&9))./54=<D>)795:=..5933@%D/4!#C1'A6)>E5+#/;D.FD.<5:/8001$#@&)9,7!B'7>!'C@*G6C"':,>HDA4DDC.%25&@!.(1-&022)>"#E=5!!$3G.=
@r7645
CCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCA
+
G3./F.@A!!D88<%?>??5H:A8GD@">06>94=74!D55D,F-#D?CH3*?4$'0-"F$(B,%65H?FD;2A&A/D3''>G>-(+&B3(G,9@247<(=(&B+41)B:=
@r7646
TTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGAAACGAA
+
:+=$D=FC$E=10/&%8C9C2>7))"8!C#.5H6*$(/5*@-0/-"))$D8!)#DF:1
@r7647
CGCTGACGCATCTGCATGTCAGTAATTGCCGCGTCCGCCAGCATCAGTTCTCTGGCATTTT
+
2CAD.%&C=<8,7D*2'"1$$H-)67DC51%DB0+.+$/";/,%,=G&BB.+,??3,'66$
@r7648
TCCCCTTANAGGACACCGCTTTGCCCAGGTCTTTCACCGC
+
4()FA;-FG70<.<>#:H,72&#;!G3"$2:C87'%&,>,
@r7649
AATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGNTGAAGGCNACACCATTGGTTTTGNCAGAACTGTTTTCGGGCCGACCACANCCGAT
+
6E0536-F<!!-;B*@@)7.:/.B*$"<*F9<G+.*7354E"1%27F@B9(/,/'>G6688:9-9/>8D)D+#=G('-+C,&8@$,-,39*/GE,;3278&2E;:$)GC?(+E3"%)H"B2<B#H3=B%'?$C=*+7#5F6148D!#3/10DFCF&G!)A:C;%>='65-8G0C@EH>6*,9G-1@:8*;C767$!683
@r7650
TTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGNCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGG
+
1>7-6+%2+9/<+D%!=("*G,(2H71/=4,+&D*F+G8G%81B7B!''@30.E6'0;7?/A)0AB3FA6'H:+5*EB@+1%*90#8@2:-'!;($1<*.G@+"E47'
@r7651
NAGGAGTTGATAAANTGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTG
+
"&&!*)$"'%$!!$""++'!'%*!($"!#'++%)"+&"'$'*+&+*'#'$&"%*#!#"+%(&!"('(+'''%&*$+"%+*&(+$&$*
@r7652
CCGGATGTNGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGAACGCAGGAGGGGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTTGTTGA
+
F*9E($D)@2%/!GA2@,8DG2H/)B;:.246-GA/4;D3=.)4+8A$>%?:)&E+B@@!A9;">AC<(1#5+/;BA+=+01?'$H.8;#7'-DD+5GBGD+B*C=55
@r7653
CGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGNCTTTCGGTGCCAGCATCTGCGCC
+
>7?=,9,"&B@+,/D=.@#5;E()=40&5$'"A+>GE<02#0<;$9AC5083;0#02D8+@$/+6HA8C#&#"2(&#/8&%1#1H8?B48!H$6*/3#0(>##,(&F(89?0G7/#+B**1C1(,;6*
@r7654
GAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTT
+
.(F@)CA/13'&F2.*AF$>8DC=D+&%'C9A3F0754$@11-C1B<F<=
@r7655
AAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTATTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCANGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATA
+
'+#)$*%!%#"**)!%"&$($+(''"))*'#$#$(*$*"*&((#"+)!"#$$("$!*"!($"!+())!'$!'!&+()#$(+$$&"&*"$*%('&%"!)"++%+(+&$**"*"*%%$+&)&#(&'&)%&)(%'!($'#%(!"+')*$)")!
@r7656
ATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTA
+
>GC*2-=.C*=@>$#)@7,16-='F,!=H7@)=:>:>3?1D*6(5??!<)06@E(*@;@:7'
@r7657
TNCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTATCGCCTCCCACGTCTCACCGAGCGAGGTGTTTACGAAGGTTTTNCGTTTTCCCGTATCNCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACAC
+
D':8.59H5&3;=9>=2%?+<B)*7,3A.)@GA284&;7'<5(A?80>E1$899(CC99$"8>"H%"=F"22)4+H(&-B$7525#$<@!G3).$3G!<-4F#@E@04<&(13&B3$#6;3C?-=-G/5B)@8F0/7EE46A4*.+4H9*.0FD14)A:A76D')#-54?G>)H/#6H68:8.)
@r7658
AGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCAC
+
0@4$)#$;H53,E$@@HF>!$DE5F%-G1/@<E5&1D-=(*CC6/F0:
@r7659
CAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCAGCCATTTTTCGACCTGCTCTTCAGCAGNC
+
)E235?69*1C4>,$!0A6D9;(.2'*F#,';.?1=0($?D'(H!5B@;,3-59"3)81?85.(+@7"%C6:.*;B))9/@$+(,(;F!G6+F/&8?3"0/<0=/5G%',:E<A'E1C7@2.0*1780**,EA$E?
@r7660
TGCCACGCGCNCCTGAAACTCAACATCGTCATCAAACGCA
+
G@7#,81&=A31@*+,4H>0;B#:=2CD?"BG"(95;!<5
@r7661
NANATGGTAATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACTCGCCGCCGACGTATGGAGTGCC
+
!'"+&(*!&'$'(%*&($%++#*"'"#+#&%#)(&(*'+%$%+!)(!'!+&(*+"+%#'!%!)%$$*#)#%$)!*)((%'%
@r7662
NNTCGANNTAGAGCNGCACNGTNATGACCGGGGAGGATACGTTTCACTATGAGAGC
+
&$&'#%%!!'(("$!(%$)!))*+"$"!*(*''#"&&#')#''$+$""##"($+*"
@r7663
CAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTNGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTNTATGAACGCTCGAA
+
@>-"+*0:2A%"2+0+E$?8=@9EA@1<=CH-AG3#)1A<&",7*%3E8%$HB*=E"D)=+#:;8>++@7963.,,FFF/>2:2-8;4'.9//053GG3%/+B).-9B*#,%6%6.4G)/?7*0'7.A@4B3C*;</4&!!?!D--!C3#F:0<D5E0D.D/
@r7664
ANGGNNNNTCNTNCNCAGNCTGANANGAATNGNGTCNANCTGNGNCNGNTAGGNCAGATATNANCGANTNNTGGNGGCNTACNGNANNNCGTANTCACNNATNCNANNNANACAANGTCGNNNTNTNTGNNCTNAGNGGNCACCGGTGNNCNNCANTGNAGTNNNANTNGTCCNCNNNNGNCNGGNNTGAAANCGNGNNTNTNCANACANCNNGTGCN
+
!!$""$"#"""!##$####"$#""$"#$#$!""!#!!!"$#!#"!""$!##!$###$"#$#!""##"#!#"#"!"$#$#$#!$"$$#$##"!"!$$$#"!"#!!"!"#!$"$#!#$!$$"!"!#$"#$#"#$$!!$"$""$###!"$#"##"#$""#!!!"$!$$""""!$$!"#!!"$""""!$""!"##"!#""##""!!#"#$!!$!$!!#"#"#
@r7665
GTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGACTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTNTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAANCCATTACCCGTGCGTTTGNTGACGATGTTG
+
@1;2-5.B@H:A2+A2)H%$>%21%B,"HCA@<>'B/B<$0,&1D.B#$?.,<D2*:&.<=6E)(C&7"+FH>;C;6:B9*76>GC"EF/#D87!2B=>8<:/B.<>1<;40?G4:A2;F2G1;HHE=0-"->/+HGC?(D:"&)8?G0<?(.9CFCFG1G,&*.',"<&%A/95!62&!.C<)/),BC$%'-'7-@@*+G0&AF7,E>,&C>,/FAF1)9476/"@:0D3D(0*)EC2?:?9).=@94'EBAG:%"%H?A"<98:1#*E?*3-&-B=+$A2$6#E/E".-+EE:F0?#19'5*4F80@!2-!,&#D@$'%(C"-3G?-=''F';$7@5F2:*%-"(!/B#?.06D%2BA80?)A
@r7666
CGGCGTCAGCTCAATCCTCNACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTACGTGGTTTCCGTCGTCCGGGCCGTGCTG
+
F4=A!:=G>*C$>73H-:#*?/76C!:8?89C41.@CA,GH.35'&-4<E+#9/E:3"&7'4?8E@5B@@H@(A616",8:0=.$)?=3A)E<%2-E0H;>:E>;<;04=+AF,6B2;)6*#1$C2/;'+5<3H@E/>?02C!81$9"!%;;B>#3%41:-3/'A3@>$
@r7667
GTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTNGTGGCCGCCGCGTTTTTTGAGGACTCTGCGG
+
+'("$"!+!&$&%%&(+'"$%!)&!$((""+'#!"(#)()%!&'&+$!!$"""$(&$%$$&'+'*%'&("*%&"+(+)
@r7668
ACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTNACACCGGTATCCCCGCTCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTC
+
F%)EF8)=12GF$=*B>2?6H'@F>46,<90-02B>G5*?7@)7*$2<)B)#>B')!:;23C=2/.32(<.4*8/7))B3/HG:-=:=B88HBG<GF%107&C44<+@-A79$'2D$G+)D99/)./(F2"D$?-"&1("*>>&F<>@D8)7)"<>C;*&&C
@r7669
CCCGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGC
+
)$GB3=?3@6E$+D?G="6D=31F<!E$8%%=*=(A*24#,1A
@r7670
CCGCANNGGCANGCNANTTACCGNCANTGNNCNNCANNTTATNGGCAAGTGCCCATACCGGTTTTATGTCACCCACACGGGCGATGATGTCAGAGCAGTNAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGGGTACGGCTGCAGNGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGA
+
$!#$*$!*)'$#)#)"&*#'$&&!*$!)$")!!!*#"!)%%$"("&*&*!%)+#*!'""(%'$$!%&*!%"%))')$$&%+)(&("#$$*"!%'$*&*)+%)!(*&#*&)"#()(%'$$)+#)(#*"()!)"%&*)"'%"!#*!!%#)()!$!+"!%#("(#('$"$)')%+*)"(*)$$&*$')!$"!"'"+)"%((*(+(%%*('!&()&$!&*'%&#&#*"##%'%''+"$$"%#$$"+"$)**'"*+$)%**!!&)'#(&$"$'"&%)%!)$'$'
@r7671
TGAGTNNTNTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTNTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCNATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCATCTTCCACCTGC
+
()%*&(""$'&$%+")(!&'#'%'$+"$&#)'(!"+%#!(!'""*!)'#'$+%$)#!"(*"&('$"'$%$#!#!%+)+%"*#$&%$*#*"%)'+(%'&!(+*!!$&($+"'+(+!))#)+)!(#+('!$)+"&&%+()#"+!$#%"+")!#("!&)"&'+#("!!"&"!(!)$)'$!*&""'""*+%'*'))"!'#+%"!)%''+"
@r7672
TATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTT
+
A!11G.'79E316C*E5)?D9'2/!+;&66!8F(<B(1ACH8%9;%<&>$03&/7':!+6#
@r7673
ANNCANGACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGA
+
!%")($(&%+*(#*$*'$###(%"#&!(+&!!$***+%))+((''"&+"!$(+&
@r7674
ANNNCCNTANACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCAGTCTGTACTTTCGTGCTGTCGCGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCNGTCGGTGCAGCGGCGTTTTCCTGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATANCACCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTG
+
(&"'%###""#&+"%+$&#'%$#'&%**(#'(+))&&"(#)#'#'*+(%"!(##")&&%&'*&$*%$(&(!("*)(+"''+#%*&#""$((")#)***)!#%"((!)+%%&!'*%%'(*$'()$'#)'+'*+)#$#)#!*#%&#%('%#'*$%%+'&$(*$&"+*+(%(*+$!!"""+)"+$'+*""%)&!!"$'*$$(&)$)&'&+'')#$"+$+&&!%)"'%&#)#$+&'"'%'*&)"(#++$&)!)!++'&*%'+)"$((%''
@r7675
CGGTAATGGTGAGTTTGCTGCGGTTGCAGANATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTNCTGAAAACCGAATCATTTGAAC
+
"9@)=(83#F;69*=%3D5=0+-E'=2?*3G:CE6D4@*>=1E;C!,#$@&28</39=#7&9665=0.*D8(F.E%9/"2**4,HF!D;',8-?:
@r7676
CGTCGAGAATACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGNGTCGGCCTGNGTACGCGTAAGTCGATGGCGTT
+
+%C"GC8>>:8GDH2.G,B!&")6%CF6CF5&0=*")DA%;96%!%20966<#+;@2&8,6727*5557?(2"556</1%.*>E;G>B(%+4*G,(>H5?=D:0?<<&4A,*4-!1)?7,2@;F8,*5!+BG:4F>'!
@r7677
TATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCG
+
2'(:1:-A4(*BCB%'5!"5@(:;3"CH?C7#+%<3/,>A33;-!%<>C7'9E3:1)H>2,*)
@r7678
CGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGT
+
7CC'":;6F$94"?!;.67H67?2B4=ECC6$BA).=D3<80#$"7F;#8'8C+?305=D?-5=F&@@E-:8GF.$#6-GE-8+AF;9?EC4@!::=
@r7679
CGCCAGAAAATTANGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCTAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGNTCAACACNCCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAA
+
(3-090F7*#:07#9(&G<%>0DFEA9&D!<541#-2.(<H(B0HHA2*)H+1/D;G=>>-A*@G(1)0H#&F>:7-?+#D(HE!:AF6@C-G$EA57+&204(%<@8;9.G=:!:+B'945.G!,9)H-(:=H%-!>.2);9CG*'2)E@F&.:1!3=BB31#,E@4"8-'===B'+5,9%5=<3@1'?FHCB/E$+;4G:%61DE%>AG#>'<5@B<'H3><#B""<8$;;*BBFED&,=2,.A?29-:(441H0D
@r7680
AGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGANCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCANCCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCAGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGGCTCTTTGGTCAT
+
5*<03,,1%E#,4<:*H)5324:"/+<<:F.<FCE5%DBF9?#D+:.$?:5@!%-/6.=!@?6&$6!8:*5.#235,384%/-">E3B@GC$)@/$#2<2;%7%'+'D($'3"!%&55!B8H=/H->5-$!3D?6ADG,51'52*4D+EH;"+!'9?(,/-()F96:1;C=113@(?8C):A)746$%2GF,,B+")4<3'0%1-&!DH6+!?5<A&'+@&39H7?B:2(A28!A8"*8458:(8)+#*""7:6AA*$FAB->(0/0'31D&5/&/2H0%:)!7&4)!*C&"#2;,<A>D
@r7681
AAAAATTCAGTCAACTCCCTGAAATGTTTTTTGCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAA
+
>C!B/*F2D5806E<?<7:D?CG<)*FEH:.BB61;".8&":#"&%894+=080$H%3@A(&@<6/2=%;'+6
@r7682
TTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTNTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTC
+
>.7#60&(%2$00A8.@1%,2043>B2@$?G=+>?C#'%>%2*7=D:2H33DF?3(B@H/(29$,0&DEC303%(H227(9FD,<5;.D(F@E6+?3.=@32H.F,A8<'FG,H<AH0=;.;1918!;>.%)6717>/H<;7.,E63<*:BG$A3=*#,
@r7683
AACACGTCGTTCNTGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTT
+
::3+G1F80$:7<51>#:&''(5F>6G),&6$5;0"'/'3A6/7547),#=&)>"!>@6?<1
@r7684
TCAGCCCCGACGTCGGGTCTGTGGTCCCCGAAGGCTTCAGCGACCTTGT
+
4?FG+E!@&@7(%.*-(28F@"G>0%1=/@&3F3F2B)A8%:C#6&A,G
@r7685
CGCCGCNTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCT
+
F0<5;>?D$%B"?AHGAD$+EA0>":76EE/%#H:&;$9(9%A5FFA68!5%&G$0($<B"GG;4!G+#A
@r7686
GGTGGCCAGCGGCTATGANTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAA
+
:/1>HH:$27#F"#"1:B#26<='(42!B:G5*(3--"&=48*')8&G+7GE4:G)%A(5-=$6@@2&C5(D"!$@AB:'*499<
@r7687
GCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTNCGTGA
+
=G'?025;8@F?G$1/=@"E/'H5"1G-2,(+;'BB2H("?F+%<;4>!&B6?8$%>@2=5;6%2:
@r7688
CCNNNGAGCATATGAACGTNCNGTANANNGANCTATGANGGNCGGNAGANTTTNNNNGTGACGNTTCAATANANNAA
+
$$"$#$$#$!$$##$"""!$$"$"$!$!###""$$$###!$!!#$$$#$!"#""!!""$!##$!$$#$$$#"$"!#"
@r7689
TATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATC
+
&+&&#+")#(!+((()''+&"(*"#+&(*%+"%'##)!%('%*'"&'*+*)%!!
@r7690
AGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGTTCACGGTGACAGTACGGGTACCTNACGGC
+
>#";19C@,/)&?)(C;92/@+115A0.45:3,EA"$:1.2BF*2:=3"%99&E>164D7?DD=D@&6;AB,
@r7691
NAATAAATACAATTGGTTATGTGTTTTCGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAA
+
%(A0%E;+59,/$=FH/6$%)!&8-/--(55!0$"/BG20D?3!@*5@+5:A'>7/F'4)>-BDA&2*?(/8(E&?"H9H*)<*5-;/<B"4
@r7692
TGGTAAGTCGCGGTCTCTTTCTCTGATTAAGGCGTTTACGGCTTGTT
+
>'"*&;31B&-/@);$7(71HAC4G7/2)=C#?9-+C!".<<.5)5+
@r7693
NCCGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACNTTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAG
+
%!E56HH:"CG$-#*D!C?/7-4B6/,H$BHH&G1>5@/)B93#$(6*5;<5"%:2@3G*"3HG,)127H*'F6AB=6/"!C8?H!1*:-+/)@F'.@*.*1&/BBEC(
@r7694
CAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCACCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGANCGTGACGGA
+
##+%'"$(*("&)%++""$'!())$#*+#()+'#%%'%$*$+&+#&%#*$)&'*%(*%"(*$+)'&&%)!#!!''!!+(*)++($&##%#&'!!'"$"'(*'(+"*!)&&%&%&)+)$#)"$+%)#!$&+($+(%&)**
@r7695
CTGNAGATAATAATCGCCAAATANACCAATACTCAGCTTTACAATATACTNNCTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCAT
+
?280:D0-4&E+(/#5%@E8"2G=)*E:8:C-2:79H(69:@<)?4<:9?12-=;F"-?*$0$82;?GDC1;-'14;;C&%DD738"+="A;9
@r7696
ATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGNTGTAGCTGGATGGCGNTGGCGGCNTAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCCACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGNCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTTCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTC
+
B+1$:-&-3#/E,)4H(=&=;"./>9A0>G+3$@$910<%12'/7163%?<73G8%;!2476)FB4H&7,>B9E@A&F')#:%75<65D(:HF.?95G96D@%"#A96%H,4@5+8DG1,H"D4.9-B<?81&7H8/"C)A?#1(4-GE:,E0"0.589(+)&096!'B'%2!/D4B$H#6C:>F;HD:0B$312$($E%-B-4EC#40G?9$3+H:"!25*>1A#+!/788('!:$>FD+G50:B(F=/)7E0-3AC9E3C1%+?@?H4C=4B?45)*#>,80G37#83?-'.1*>5H.5>2?0@&G41*0+64)35FG2G%-#94C#!?A%-7->C,'*@F>.%."0*>%$*285A11F@/.F"F,=/'1/D;*:@E/.+&9H2*D5?HAG(9H9.,E,><,9.>:42#$(5/-,:%+D5#1@&A%E3H7,BH.C$5"4-D67-
@r7697
GACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTAAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGC
+
9%9.$5G!#94B(A9<!:*3;@#+<D%A).$&(#.766)F:?$",'.GH++C%<G3!0$:%=/E7"2?&0(>A**.'&'H*6/5#@:*!=E"BHA:3?'H*FCA,$@!%/*F!'!4.5CEEGF4-FHG?2(FG@-0&+;//E*6,
@r7698
NTCAAACACTTATGGCNATCNAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGNAGCCGTCGANGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAG
+
!+%6H2;5G5@+6%78)<00((?;)/E,<;.:+<E;?.:?B$3(E17"<?)6)&H,)#%<D,"@1"3&%G"5#0<8F98.,7H3*$&..;BF')%1G1A0<?BBAGH9F4''<6@%CBD-1?(3
@r7699
AGTCAGTTNAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGG
+
>C6"<$)3+02%4..&2/$:>?B3@A3)3(F3D-:&:!$B#(D#E)?CF043"A>C>?0.$1&G<3F:<#3C9D!1F=@?B<"@-7,.@7+9+:C!?%;<;;>1*4#7+@%(59$$/=.!!#CH?""!7*"%,%
@r7700
GTGNCNAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGT
+
)&#!(+++$!#$*%*$!&(%$$&&!+*$#*')'!%#'(#&)%%!&+"(#&&#'#&
@r7701
CTNTACCGCTGATTCNTGGAACAGATACTCTCTTCCATCTTTAA
+
&'+"%(!"$*#)('"(%+#+%&'$"*&%*!!#%)!+#$''!&()
@r7702
CGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTT
+
=8@(FGA*.?:1?G+87F%;BD%".>&'6F%'$-601&86>:H),6!5=>=09C%D
@r7703
TTGAATGACTTCCCCAATTATTGGAAAAGNGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTG
+
/>B9#*(0(89.:*CB2G0&7$63G.8-42;6#=>;)21>,037)#@H1@=/5:;*&H+-;$1=&7(8>&D0-&?"=B;G(C*=)6D'.%:81.:A,,?,CG#96-34/@6:F-*4%E;$,!+B&)FGC(@@'5&>GA&?+H347:A<7B6E
@r7704
CGAATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTG
+
9<:;:3<;%3&,G;8?AC-17#H4,'/+A+4&;=1<"H5C2DC2+3F%C?!4A&%</4:8.'$1:A!.F&3A;=A/*;#::G9A9D,:+')45)6(1H/43E.EC>/D=HGDHC16#!5/!G"(:)%AF)H?F)+F3=
@r7705
GGCGAACGAGGCNGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGANAGGACTGC
+
CFG*A85B$50F##;()<'B@454!EE&"E"%H1#00#@)6.;)6C/2(E/>D.B,?2?C;@8DEH?>D".DA-/6&$)4#.E66(9A#!.B2
@r7706
ATGNNGNTNCTGGCAGCACAAATGCCACAGTTACCGGGCAAC
+
(!%!"&"&!(#)++'!$%$*#+%&)!+%%!'))%'#$($!"'
@r7707
CAGAGTGCACAGGCGCGCATTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCTCTGGCTGCAGNTAACCCGGCATCTGATGCCGTTAACGANTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGANACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCTCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCNGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAG
+
)CA@+H%*/;1&1&;9/@;,)0'?B;6H>(&;$2?:>3%,D;:F+A2;1+:#.2"$=!$F>##((.$+;(H<<2524=/))0.%$(."4,>6$B:5='DC35:<G8?,C";F@+0)>)8$!!@8BC"-C:.!E#0A)?=9F$G6(7;$;"52A,/+?02EHH&36D;)('D1(#"E>52,57/#&?@>(06(8!$H+240/%(3,"%!-+?2>:F7/DH3H<F@7:?*4CA3(&;&027-'>,7"3$ECE;8B!%C%'&>/9;1BH"4%9('=:#H!'!&)&3H;',&$)0<:$+0A)G2BG!:E"$)AEF:;F$9+)#@"-5&61G$D<B)7%/58+@
@r7708
GGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGA
+
5&F28G=#H*7%*"G<;@%C&E<5.*#+<6"*E011HB0-
@r7709
CAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGGGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGGCTGTCATGGGCTGATAATCATTACCGTGATAACGCNATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACANGCAGATGCGTCTGCGTGATGTTGCTGCGCTCGNTGCAAA
+
4#G,,+;7:)+01&10599)7%2@;:;??%>6C!'F--5:"<(F"?3).3,H?)@#B*=9#/5-=F-*$A>'6F5*+$27)9D=':A7,:9G3+,%,:*4?E2C<,91-%-.=HE/,-'+./3>?(9/3'.4=)C@;$7;*:62!494+F!BD*?11<'$BB<%>19EG6(>'1('1B*HC2F0@<'=@)("F>4>C(333738/H?*06::)?5B?!=H/:8:#/*=--=)2:?@=4>C.D'/*(B;+**1,G+7+$"=+F#&/=91>%=:?*=H<D<)>C4E))$;@3?";)-(@$%7'83%,/FBB/B
@r7710
ACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGNTGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAA
+
%++$&$!("!'(%%)+*#!"!(+$!(*'&*%+&%!!"+%*'$(*'&&!$+)!"!!()*"+&%)'')*"#!#$+#)%**+"&!$"(#$$"%*+#)&'&+(("#%')%(*"$%*&%++!)(*!!(!"!!$!""#+!))+'(#&!+")#((+#!$+%"()%%**$#)"#('!!)+(($("%+!*&&#*)"!()'(&+&'&'"$!('')'#'*)*'+('%$"'**%*'"($'#!&**&*!*'%
@r7711
TGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACC
+
@"(D6!E/'40<@"&9-,>15:C?<93-31.4'!8">C$6;*F>8#=*E9$A%E#7).B2!,5'H>-(BA$2+*B#E)0)/84*"096>52+A!>$65G+B,>1::H<0@6)0/5&!E/)FG7C5;G-AE((!?,,7->4""'B8"'8H3-E:-/2=E96#3@1F)9)D*FG:B/CE9HA0?8
@r7712
CGACCAGCGGCAACATCATCACGCAGAGCANCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGC
+
>)3$'B+0'D2F&</)6,/D1F%)E<@,-.D*5"43!5:/:&0%A#=0<+'8/8A$.;5$?B)5<'6<2/>)(H?C*?CC(4A545((-9.F?/D#!!'HD">/E>(<>3F*0A<E(!04&1
@r7713
GAANNGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTANGTAAACACCAGGCATGATTCTGT
+
)('$!&+(+)#+!(#$&*$((+#!!!%")&%%"#(#(%!%$$'+'!"$#+$*)"#()("$(+$*$%#!""%
@r7714
ACCGGCAGCAGTAGCANCAAAGGAAACCATCACCCATCATTTCTTCGTTTCNGGAATTGGGCAGAAGAANACTGTCGATGCAGCCAAAATTTGTGG
+
-7+-AC71%4#'E-F,GB*&(E/>*(8GA13)15"<DE#8#F1,%-*?'=.4)"?#>4>@#1GA.H3GH"G!$>,9.%A/(GFF40$B<8*6@&$!
@r7715
AATCCGGCNTGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACNGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACC
+
*+&#'&%%$"("!+!*##$*!""#+(+"*(%%$"++!*'&""""''##')(#&$#)*%"&"'%)"+&#$#!!"+!*!&+')#!+!)*('&!(*'&%$'+*
@r7716
CAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGG
+
'.G3*C8FF:*)G(.$H/B@FFBB'D(3+A$37#?C+:=,'=E+$*E1,GF!?770GB5A0?;AF:)"HG
@r7717
TGGAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTA
+
)*#+&"(%!#)))&+'#%&)"%)'(("!*&$*&$%"#%!##*''"+!
@r7718
TCAGCAATACAGGGAAAATCTTGCTAAAGCNGGAGNTTTCCGATGGGTNACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATGACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTNCGTGTCAGCACCGGGGCGTTG
+
F&>?!&/'2:A=7B850F98@*$$="*/5@9>&A'C%B#=*8B92.B0!2A<$">CA$&H<"2!#:1#>E=E;E!H:+89F355-'C!?G'CD6E%-67.B6A=D70>B/)26735=>H@B7.G)8<6C.G!,/1'+11)?-#%2+A-5#F;)(>G'17><13F78BB1G)H4$8&<:"2?FBB<D5G,;
@r7719
GACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAGCCCTGCCG
+
/.47#75B7GAH97$#<"C31D..40+9".)&(%H<=4.G(3F<,&D694E5,8-+%$,+$2:)':6.);,&C?A;>)!&/93B'=(<2)D+"5A#D>;C1:FB$&'9C+5<A@37"-8D,<F14HB7G2#HC2
@r7720
GATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCG
+
=495*;;%(9&<1!2?+GA4<H'6$@#;-D"1%"5B6@B>0*:-:))H%
@r7721
ACNNNAACNTATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGA
+
%%!%)#)#())+$")'$+*!*$(%#*$)(!$!#"%'&#)"+!&!$$+!!!((&#)(&*%%(*&*'*##")$%"'&"'++#++%#+#"'(&+!&**&!)!+)!)!%(!%&%&
@r7722
ATGGGGAGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTC
+
4F16A+*H+%,!36;&:869!E(B98A+-FA*&2GC*?B244C7'A?7#(<&?6@%:.<*0ADE-:;+4'891B36?#"6$'C:.024&1C/H
@r7723
GGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGNTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCNAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCNCACCCA
+
F,":"*(*G!647,B?-'==&8+@40.+6E4!0D.73G,:?':BA08=4$;5'""4H%FG>*7"985;3C%9?B&H(*/!0$@4)>2/CE%&9H9($E3$975>!:GEG&-2=H'@0F4#6'$6$05G#+$><=6<@'2/6&&28!D;$<1'!6=:D@(5;!*%9883;,G+HE%+%(*;<C"-!7H
@r7724
CTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCTTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCNGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATACATTACCCGTGCGTTTGATGACGATGTTGAATTTCAGGAGCGCATGGCAGAACACNTCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTNAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGNCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCG
+
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
@r7725
TTTATATCCGCAGTGTGAACNCCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAGGGTTACCTGGNTTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCT
+
(++"!"#'+($!"##'')(%*##)&'%&*#*$!+)*)($%)'*$$#))"*(!&(%!$('*+"'"#$''!!%$)#(#$('$%&))&+%&)+'#$('#"+$%$%+#&$'!$*&#$+'%*#)"$(**+'(#"+#*#
@r7726
GNCGNNGGNGNCNNNNCNNCNGCNTNTNGNNNNCGTGNANNACNTTGNTNTCNCTNTNNNANCNNTTNT
+
"!"#$!!!!$##"#$!$$!#$#$"$$$!"!"!!#!$#!#$"$#"#!#!#"#"###"!#"$#!!$$#$"#
@r7727
CCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACATCCGGCAAG
+
G')3B9#";%GA+/1#<74.4*>E5>06%@='>GBC.$7=4>,E8045EC1#<7;84+
@r7728
TCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACNCATGGCGGCTTTATACTGCCNGACGGAAATCCCCGCTTTCTGTGC
+
2"%>D,%-8?4%<-"?+F5:,F>,=<5F2'4A%!(>>1E)/3*62EG+':BH)BB!@91EC*2+F*F,E.72,*!4$7"2G/)$H11-<3.>2>(4-<)"BA"B3(#?>'E+
@r7729
TTTCTACACATACNATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCG
+
/?3H5A/:=+9CG$27%F@C&5.H$*0((AEG?7"*00H,D*A08@H>4$G5-*C;'<F>;00?(43!B"<4.!.*<
@r7730
NTNATANGCAGCAANGCGNCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCGCAAAANAGGGGAACACAAAAGACACTATTACAAAAGCAAAAAGAAAAGANTATTCGTCAGAGAATTCTGGCGAA
+
$""&"(!$%"$&%'%%(++$&""('"'&(%""+#)$*#$*&&$+#%(()'$!*&*%#&"&)$+')!&%""!'()#%!%*&++!&*#"(#+#*!$%'%&&"&(""))%"#++%'*&#!*+&%%$%'(!&$!$#$#*%!(*'$!$)*!!*'$')"$!(&&%"*())%!!#!%""##"!*+#(!$!#)&*#$#!!!!#"&)!!%!"
@r7731
GGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGNTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAAT
+
0F"*'@+9%B2G/;!<)3;"!E%G0=,46";$<!%&C%0):3CAA5673>4;(+@?;0/?FC@283:4B%H('ABD!C34<3=''/)G7>E&H';0'+E:1H>4'(*0G&<6)?15%GG&B6$A(9>#+6>D)+05>$F5#H6(@G,"=H:A&+?B-H>B15;+1?<F;/7!(-0D0!6;!H7'C224)8AF/?D'0,%E
@r7732
NNATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAANCTCTGGTTCATCGAATAAAANTAATGACTTTTCGCCAACGA
+
%!+*$+'&*+#()(%")+(+"""#'&((*"!'()")*""+&)&&%)'!$($+&)'*'''(()'&#$"$'$)*""&)&$'%'%)''!(&)'&+''%(%$#+%')
@r7733
CNTTTCACCGNTNTTGTAGGATTTGGTACAGGCATAGCNTCCTCACATTTCTTAGGTAATGANATAAGTCAGATCGGCTGAACTCCACNAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGNCACCATACTGGTGATCAAATCTAACAGTGCCGG
+
*))%%)#&"'"%(#(+!#(*"&&!$#&%"&*)#*+"#&"#+))+*#")'%"""!$&!#(*#%%+!!#'$#(%)*))!%("*)&%*(&%""(('&'$!()"('+"&**(#!')&'!#'$$%"!'!%)*+)&)*)%+($&&+&*)&!))#"$(!%!$*!'&&#$
@r7734
GTATATCACTTTTCATTCTTGCGTAGCAANATGCCATCTCTTCAGCTNTCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCT
+
+&'!!'#&$*#!+!"!%$'""!)%$%%+%"&!(+'()+)*(&*%!%#!""+)')(%*$%+"(((**#'+"*%)(*%&'#$$!'!#*!#)+%%)$(*"$!!#$+*&')'!'!))+%*!&((#$#&'
@r7735
TTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCA
+
9>$'$04G7D-58A4$:#&59319#';;%>H5,0E1DCA.42F$*!BC<6)>%9#+%44C*(9@961-1@%,=?<E%(%F'644!+4F&+!6B@AH8$/%2/B)-1-=$!&3)7E/)/+>2'D2
@r7736
GAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGAGGCCATCAGATATCGTTCCGTCTNGCTACGTCCTGAT
+
;>6,(#D$>)',9$870'H/&F2-A=EGA17755)&C!?-7<)CD/'F!&,,5&)D9$F7"@B/&+"')'/:
@r7737
TACGCAGGCCATTGCCCGTTACGGTCGTAATGNNACGAAGATGGATGCCTTTGGNTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACANAACTGCTGGAAACGCAGACCGTGGATTTC
+
D@4">/#!E%?F740(1&<$?AE0?"<F9@4)@)HD+(/)A@;<BD)+.A<1H5FC!EF.=GA+1G:BF:59C8@:4B',@*=3D2/!8@-$G-@C'%)!#+>!,A@+:E@/HC:4F"?3;:C4?G@+%067/%+G
@r7738
CGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCAT
+
4#8"8@:'8>><:(??8):5,#%.7;:$&+3E54))/1%G!00A1;72H=/7!>F!G39E."D";,>/EH22"%-)!H6""&C#>2/7AE%<H&&0GH,40=+E#+EA%0B1H=G;$'B=AE85!$H.#,C3?$56HC6C-EG10022%'DB5-2?/;!$,F?G"'-$C,-&(.190H,6F5EH>2E&./;,86/!776GHACF)6?G@86?877F#
@r7739
CAAACCAAGAGAGCTAAAGATCTCGGCGNATATCAAAGCGCGATCAACNAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGA
+
36%+=91)E)2)0>0%+>&13;D,B#>0?4:2==/30:69#?@%=1;59!*88E@F89A/-/""!0B">/$1!E8>?3G8-1D5D<EH/8/3BHH&8*G7#:B?$=*;*E"(+
@r7740
AATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTCTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGC
+
8+@(.30+G8,A1#4"):)?(08B@)?.=;=:*<0-#G@E:-1*",2*>4!E#*"-5$71"!D5,%+G?90.2#6A<=G2:>!<59B8;H<BF@,@=?;D?'41.5?=48!':,$>.5C#E#C
@r7741
GTNTTANGAGGNTNTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAA
+
$$(')&"(&#%#&%$+(%#$(!)')$#"+'+&!'##!))(&$&++"*%"#+++*&*'"%!$)"+!&%*""
@r7742
CGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAA
+
<+A-+/'<!!-'3:E4"+G#G?E?#!59$C@5?<51BD*A6?!&!3*+#GDH#&)3=!2<D+/6)$!,4'D+D*-6"(!%=G,*>#F6*%@.6*/'>$<52/=E(HCE<:F:=,C!6'=E$G
@r7743
ATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCNCGCAGCGATGTCATGCCGTCCGGCCC
+
EF/!=)*;/AG=G/67(#E99:+7H876E0<D,<4:.714)*+%B*6<!78-".%)-3"2/7.F8&7,/A.!HHB,G#4+(%8G!H.4FHC=0G?'?D4,8779?;F798>9!)7"4+0C%4;"#0'.6',C8!:&1)H%,
@r7744
CTCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGNGGCAGAACTGGCAGACGACATGGAATAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTNTGATGACGANGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCAT
+
"&F03D'G.=%0"0+0*G-;8E/?E5>@E?$-/',7"$@B;)$3F*&%14)2:$:+@-+<1%GEF))+.B?C%F6889*#56$?>;@;E'5B#.,*C.D*/%D<%2%9!B0'F!3F&4G&>G'"8@CF=24:<&4&H1E4(HD<;?@9)@")7&B5#"!6=;".8$72;<./"?:H7&G.=B>G@8/00.893:@,G,$$"0E/2#%3:<8)9H8.4C#*G!>04*6*;GC(1)!,AG07D171%?0$6
@r7745
GCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGAGTACAGCGGTCAGGAGGCCATTAATGCCNGNCTGGCTGATGAACTTGTTAACAGCACC
+
+!*'$+%+("$*)!+"#$$*+$%$'&%"%('&!##'$"%#(&$(%&*#%""$)%%#*#!(!(#'#"%())($!&)+$()%)%#&#$$*&)$')&$!%##'#(%%$&$!""$)$&""+($$'
@r7746
TCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACA
+
/>;.!9G'8?3768/(DA>5.++%@2>>H>F>:DD7:/73D0/CE(&C61=6FG6%98:2+55G%>/"0H!6FE0-6:#0H.6.:%G<4A00F#81'C0:D,4%8,#DC",76*,*-+(7>:;0<2"7'*"'63G;E?F&4AB;3@B?0.-9,4B$(>/+6D.=B+D!1D6#-;43G(1%+D2&080;F5.,G335#(<'1C3<)".%=48/02H5C3@7C;@>,';
@r7747
CNATGGTCTGNNCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGNTTTATTGATGGCCTCATCCACACNCA
+
%&**$&'#%)%%+#%$(%$)$($)#&)'$$&++""'$"*$$*%%"'!!#$+(%*(*!!'%!!%!#(&"&*&)'**)(+(+$!!)$%""*(&"&+!*$!&)**!$)&
@r7748
CTGGCCGCAGCGCTCGNGAATGATCCAGATTTTGCTACCACC
+
F5;>*++)(32H/5A@0&9/>+1C6!2+<@@@D*=G)CAC<;
@r7749
TATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTC
+
71-.#88&#F<B#)<8?*&-D>C%<GC$3%:GHF.)&$>294<1!@CC-
@r7750
GTGTCGAAAATACTGCATACACTGCAGAACATCAGCCGGAACGCGACATCAC
+
$))%$+#)$**(%"$"(!*(#&!%$"%&($((*!"*"!$'++!$+''&%'+$
@r7751
TGTGGACGCCGCCTTATAAGTGGCGGCAGATAAAGGTGACCTGCGC
+
8%*B)!0$<7?"%D*23E$?"%6=93#F:=/?43))#2,<!6(*<E
@r7752
TGGATTGCGGTAGTAAAGATTGTGCCTNTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAACCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAG
+
F*"=5#%$H4279$"*$+//A3&C47#<5<@3G?#&@9&,<@C>*A/(;-3+:8C;)&2&#:+*">FGHA2":=6$?#8,&>6;#74E:$:-E$%!:AG$AADD7=>9B2=8C6F3;B84,F(#1$(>GD$><>0D!!$.95G(D#@D#:0*7';9C,*/9GD2DCGE(;@3G9
@r7753
CACGACGGGTATCNAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCANCACACCGCTGGCGTTCAGCGCG
+
.+(,.'B@**+6%>-:G?'4C#.EE7DF<F!#<+E.+,2F''B'9>1@&.+G2%#55B=)G:3&;)21&7=5)#+"C$*!FF#66:HG3E%('5,1:)*G,;H/(E:
@r7754
TTANCANGNGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTNCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTATTTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCC
+
$"$!*'"'"&&&++')$!&%)")$*&&##&+'"+"))(#&%&'*&%"+''!$*%%$)()*)&%'$'&(!"$+!*+''#'""#(!(+#"%(*(**#%()%)#)+!'*#(&*!'$&')$*++#&&'$'')*$)+&$+('$"&)'%')%))%+)#!''&'&'*(&**%++"$(*&"'&%"+(+!"(+&&"##)
@r7755
TTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATCAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGNAATAATTCAGGGTGAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTT
+
-.2=CC?.*=&*8.E5*B1EA2:E"&4;B4.?-GG=9&(,-'*2=G=3A8:"><3D'(68%#B!=#@2!:=E!$3'(%F*EFH80$&'$HH><"B:*>6&?,3FF@27)*!C&2$3&>::2%.>%FC3F>*2%3D6:/*E;7!(/(:#+&5%)20*6D>8C,>+B4H.DD')%@&.2767-=(D(*-*!!=5,7=8":H=4DD5:17"<
@r7756
ANAAANTTCCTTTANTGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGNTGAACCGCTCNGACTGTGAGCATGAGCCCCCGTGTTATNCGNCGATTTGGTGCCGTAATCGAAAC
+
*$'''$$$%(*$*($)+)'$%(")+("!(&(&*'**#)*%+)*(+!+*'#'%'!)!)&((*"$!+#$')%&)#"#"*#*&'!+"+#((($*)&'$'#!!)!%*''#$)##$'%$))'(((*(!#%(&&'*!"(&'#&'#**("%"'#%!*"'#$+%!)')!#
@r7757
AGCCNNNATNGCNGTCGGNNCCNNCTGCNCGNGCATTGCNACGGGTAGAGTTGGGC
+
%('&!#$**!)($##$!#!&'##!$'$'##%#+(!(!%""*%&&$$*'$(!('"&%
@r7758
TTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACTTCTTCCAGCGAG
+
2F*D92/#6?584-?4#:!)(3=?,;)C77C9)DG14)50*'6&01?F<;+:E3,D@6?:==;;C'B4BB"$)5)B0;)@)82-*"*(3/=676E+E+.D/(B2,FGD&;.%=3
@r7759
TTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTC
+
3E+?9,>E##5*,0#"@-4*CAG5<'2593A0A=?>(>AG-FD.)-9".@F9(*3*&;)/+6#.407%
@r7760
CGCNGAGTNNANGGCNCNCANGNNCAAGANCNTCGCACCATCAGCCAGAAAACCGAATTTTGCTGGNTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAANTTCTGGTCCG
+
(($#$(%)!&*#)#"$'&'(##$!$(*&'#!#&++#"+%'*"$#&'()'*"""""*!)%(('+*+!$!"&*)*'*!"%!"#%#)!+%&&$+(*&"'**!'"&%)+%%#*$)%*)+&%+##++'**%(()#%&%+*)%"%%&&$)&$(!'!&"")&$$'+(!+%)#'+
@r7761
CTNCAATCGGCCCTTCGCAGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTNCTTCCTTTACCCCTTCCTCACG
+
$%%+))!(%+)')!))##'#"()%)&$"#"*'#+'$%#%'('*(&*$&!*(%')*!%"%)"+%)*(()"#$)"%'%(#%%)!%%)*'*))+*+*%))(''"%((&!'!)"$'!!*%&
@r7762
AGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTTATGGACGCAATCTGAGCCTCACCGCTATCCCCCGCCTTAACCAGTGCGCTGNGTGACTCGCTGGTCTGNTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTG
+
-F68C8.H!&D85=(/H&>CA(243@.&B.?9-8C22>)%(HB#)7,#'E&?/A/F-(@-!%2>6EBCBFB%78."=8"%&!E(%@+@$@;<9)-+<D(#(%<7-3+?F:B>,$14F)E#!&D@8)*..-B&<80,)?.G->"7@;/<C-:0$.+DH=1G?<*<8C(59(/AEC9=G>&=$$E<G-=,8,(:H+BA$;
@r7763
ATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGC
+
-7;">)??2"(B0,;2D>8#(;0A)&4938&+*,2%&6B=>&@H+?-7HDG9:E04).(24$956/6.*0.)?/
@r7764
NANNAGCTGGCTTACATTTTCGGTGCGAGTATCCGTNCCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGACATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCNGCAGGCCAGCGAGGCAGATCTCNAGCCAGGAACTATTGAGTACGAACGCCAT
+
"%&$)&*&%'(*"++$!'(#'&$+'%&%$#$&$$("*$!('*!(&$"&&("#$!)+'*!$#$**)#('*#%'#!#)&+)"$*#!'$%%)#(#)!$##'$&'(''*#&&$##+!%+&+(*+(!'(!!!"+&!'"*)'%*"*#+*)*#+!$*"%$'##*)")%*%!)"%'*$&%+*"*#%*&($+&!+%(+(&!%*!)"%'%%($&"#$'')#&!*&*((#$+**+$)!&%'%#!#'&!!%"&(*&)(
@r7765
CGCCACACGTCCTCCTTTTCCTGAGGTAGTGGTAACACCCNTGTTGGTGTTCTTTCACACCGGAGACNCCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAAC
+
87<82A=.>9*&.5$+>-)=H+8!BD+40=1HDCC$G)-0661=F:;?:2&>12;)4:***3<1D7")E5&/:@33.%$#C.H<=+/B!A/?B34F,#''-,$#A?%6?H$-G02:;3/21HHF>04B%%8F+H-#
@r7766
AACCTGTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGA
+
?"G2@*AF1$F9$9;C&1(('),98(*:;5/#8<->6H4&C;=:@;H5B5
@r7767
NGACGCGCCGGTTCTGATGGCGTCTTNCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAANGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTC
+
##CAH+)C3)GA00''5==F/>-FDG=6E$/"<:87$/#?$65+.>8---!6BH$HD-HE@1G<7?0>=F6EA4A87600D$>9'@9?&9)6<$+44(?,+:226G&'#C59:E*;>F:>7E?'$@$,7EB%--.2?71D;*60(4&#?B!=-=-#?7")H>F-7G(=D9ED<0#))9"A!F7
@r7768
GCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGNCGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACA
+
29(+'6'+<%>95:42#95H:3A$,D&3&25?A)">94+("+)=),)3EA+*=H:$<*7*D8>1#"%/',F6DA%/*B%C!@B"-51AF,9<F4(#4G@@<",H98#?=11$#;)FFF%>10':?/H80G&C0:$
@r7769
AAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCAT
+
<;=70<B"F8?:6>/H8E5#+(H$@</:@+BA,9E,3B2#;7.)D=B2*#8E9>%=/<C8=.-G&5(:
@r7770
CAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGA
+
)(+8*@F*/.5%@+C/'1+C(+F1:E/837+GC"E*1H20%<%D4E/(5'B*8&.E()!F);A?D0<)"<#+*>F1(B!/2;9#92G'4
@r7771
TNAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACANCCGGAATGTTGACCTTGCCTGCAGCA
+
0&"E>-!$#//&!70.-2*;46%F"!)2"0BE"5=:CBDC#1<@+8-7(824C=:5993$'$=/8#=#?GBG46?9"%!+!,G470)DE+EEG$#F2D3B*>H*&A!=:3
@r7772
ATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTA
+
)&HG,A3;(00#-5;!F!,">-$(F&EC$>9%03-B.%9D"B:>?<<%&64H$243,,#,@+0@.#?1%=B!D!!C@.&>F(4B;)%:!!<D"2?E?>>*$9&-)H#'F<1D=F'0%8)$HBB
@r7773
AATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCT
+
"$*+%&"('"((')($(+)&""("#'$#$#)(&)(%&)&+$)')'*!"*(!)&"!"$#(!!+"%'%+*&%++('%"!*!!"$+))'&$$(*#!*%+(%*!)&$'#'%%'+&)!+&&)*+'()!!)(&+)#&!!**)$'#&
@r7774
TGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTNATTCTGTCCAT
+
#A;&?!(41)F(1:"1><9/A(*%E@(5&82:H73?0>'D$+@HEC9+
@r7775
CGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTTACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATC
+
HH?1D@&@7";-09-?0!+<H:*;*+A3A'+378$-=E:>;-F!(G28@-B2?:11(5FF$09$,<,G>F&-%24-(.@409FF9>%G9#2/-?#E%*7$0BG#5'<3;?E=!@5.7>/*@F8C9'1/&?A"/0!+8,1#<@@H$73)%A43.@
@r7776
ACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCT
+
H4+2$84%5!./;14<3:+/;0#2<)E)G<.5$C'F;,52.E2A;!/4<#G5*&:0$A.<DFEBF+/+C#9D<$:&5'A9,G7*FFG+
@r7777
GCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGC
+
C+/HCG.35E@451(78&C6-?4/*#CE)AG8)78;",+FA1+G#?G(>
@r7778
GCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATNCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTA
+
+)!$$&)#+*'%*$)&)'%*&$'&&"#+!$"(&%!%'"')*"*'"!)")()+&$#&)'#(!"%$$)$&!$'&'"*(#!&($++++(!)##"%&
@r7779
TACCTTCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGC
+
+1*H592#H@6!/.:9FE?348G"2)FH&7?4B18%-C@)3B<*8,?G14/-61
@r7780
GGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACAT
+
981%!::/6B1%=BD1'D)18-2#+'*!?C(H$2$)!C!H
@r7781
ACAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAG
+
!%HB3)G;.A9:H=1"19G);-",7E,))#1F'5$($4A4>*8#5A"!D#@?HH0:@C10HE(,).$C'6/,C>9?-#2,<&;*)"":'3=?5%3/61G(=9#HGB=?E-7<;;<-''-90+F%2/C$(/B+;BA6074?G#C>;?"#7-,HA&57!1H$1$+?G3,3E15'7H1@@*?&73+H,
@r7782
NGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTG
+
"@B5.%(B1<+*$57$)FAB0'';<D9=GCG2=*11E>1H8C6-/8+&>EG+(&*>.%2B*3'6<(#0*#
@r7783
CAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGNGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAG
+
?>?4A1"%+A0B@$-&)6$4'%>C"*:-6755C)+.G"53?G8.(B;&58&#;F3<'#*C'(-F2G3?03:$<:F//?8H=-0?B"&0H&')+!!*""0-0#:/)"B,$?,>2%/A.6;5?()$,2;0034>/5%DA+(3,/.>@B0895@#?+6GF"?610=F8%9"9'-$1)C1-$B'(+0;=>3&=?@H0-F
@r7784
TGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGA
+
+<DH4*1>G':%35%.?:$.?)DA/<@E&A14A%GFG-01""(
@r7785
ACGACCGGCATCCTGTTTTCTCTCGATGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGC
+
+('$"'*"'+!%*"&#'"+%!**"&$)$$"#(%+!+$$*(&$%&("*&*#'+!%%!#)"$&!%!*"&#!%+'%%
@r7786
TCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGANTACTCCGATCACCCTCGCAAAATTGTCACGCTAAACCCAAAACTCAAATCAACCGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGNA
+
&?09+=+68$091CH!6:+!A"D?=HG8$4@;)@7G/07@>D@<$,6;,<2C,#3>109<@*=G"A9<1.-5632<4D2:'9-G#.!/<FA#;D0)G8$>;4+G@A(5&4B(:'#=>-(H$23#E7E!2?F%GAH)9(96/H0E9E>*!B%DC+-C*;6!0(:!G(5--<D"2GB!-<99))*&D;C=
@r7787
CGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTTCCCAGGANGCACTCGCGACGCTGGCATTATCCGGTGATG
+
4G.$>F062<3/4%:?&4/';=4C9)=,5;A/!:3D(!3$D;&5E)/*C/EE!B%D8=B)&A01C4.4/@%>8;-'-C5&G&#E%#48%2%!!D8"A#B)69<A30A2"A,5H4:=FG
@r7788
NTGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTT
+
"&4$*C4="=2(:H,/?/3H#,5!*8;+G4CC>AF(03H<ACBD.CC,8
@r7789
CCNGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCAC
+
#("=3A/)@+664DA,;"(<$D";)6G2?-+AC2,@>";%"=!0B"'('1/5=%*C6H'=4?2-CA8
@r7790
AAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGNCTACCGCAAGCAGCT
+
23AD3?3%14,A*F5A$2.D%013:76@H+.G;%B3"(!D+F%88)G4E@:"&-(&$!3(*&52>H&HF,%1
@r7791
TTCGNNNAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGT
+
$#*'"#!+&)+$#!$()"#&&!))*"%")"'#+"$!(*+"+$(!%"!"$"!#*&%$&!)(&!%+(&%!+*&%$"%)*#)'#&$"'##*&(%#')+))+)%%)#!(&'&#+(#)'"+!+#(!"&+#+*+)$#$&)++)*#*(&&*%(+'#'*"'#(
@r7792
CGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTTAGCNGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGC
+
01$B>5"""#5=67B+E=?H4.5F"-"3'3GG84:"0/<+8"'3,1B',",/*(#A*G+@384'0E,G"G!-&>2-H$AD6GC9D
@r7793
AATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAG
+
4"+#21EE"D&H@B;.'C075%F23(2B/EE>:8>6'0<E$'G26?F/,
@r7794
ATTACGGGACGAAAACAACAGGCNGTTTCGATTACGGCACCAAATCGNCGAATAACACGGGGGCTCANGCTCANAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCNGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTNTTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCT
+
5$-97='';'38!#A1@ED84:<0"B453462(6>9E..;H8A!!#%@33(7+@D<.."+#3+&/%$:&/!+3)&%)5A?4BD1D/G=F5"9%%5.%81AGGB21!E675?AE*14$'2';C99:,=:;:94?(H4-(/5>79D@<3?(>EE9+&-;<,<!402!8?7129)-@>E:$%$6/#'4?F4814/.0>?!%)>'<H87%5A&"1=!6*>6(46=4!0'D@?C<;"4,G?3#(66E@:33DH(&/6>,;*%@H2C.&A#7:=.*04)8H-&(/@$H!4:H2C3H;E""B$(7:0:5*"(<;&/F@%E#.@7DF46GG7"C4E>9610H?57,3%H=-@9G@BHC$36%-")#6
@r7795
AGGGTGTTGCGNTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTT
+
5@8=*,@+?+>">%9+=6545G78#!>F5?#F1H5AG0%D!6!B1)@>H)<EA*99B(7=5F5;790$$8+6&4%HA-*BB2H?=0.$0A<:1$=DE%":#*/-=B!9A7'>.*):8E=?D371/,12@5#;&E(F'5("$";B:.C963(
@r7796
AGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGANANTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCAC
+
5G")EB'5.;/%*%"6(D.++-)99A?%*A#&:(-.C,5"D(+7&8;=446D%@;8>(04%H0+"*7H@"E=(B&-=(1B@"):GD6+$A&;B3:4<
@r7797
GGATTAGGCNGAGACAGGCGAATCNGAATCACTGAAGCTATACAGGCCAACATTGNGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTNACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAA
+
+A;8F-AF5-4CAH+%E-36!%/469-93+!9@8(>B"*-,@#F/G@&3*)FG)/+ADG;.9A$E2C$=E86G67*#)6>;/),!9#@E6)9("'193G.;54B:B*,+5.:H>"C8,'+BG9F?$9B=)HG@A!>+3%(54422E9H/;'%D5*8GB"1;"-:4E2F"E-.#H4*282?,3'4:+:1B1&4-'B/)!B)?=2FCE?E$;1;#)</BH$:(&&#"7/7;<2%=*$62"+>C93.9$.)2G*?*0=;?+,
@r7798
ATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCT
+
7++-><C3.0$>9C-)D/"/$7,%A+2)/0/'+5@>..("(-,<!?0"A7E.E!CG(*?0,F&5!22HH6,4*H5'"G,>$23(-ABG8B@C<1/3F<.0CE9"6!,"*"H&211C&38&/:0#+!"
@r7799
AAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTG
+
6"3?'"*,;@&$@B*!$03.E-HB%<="F/<3D=:'55$<+BD7=;B)D@
@r7800
TTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGT
+
4F+E>2FH;"<3B$06?G,D0:<01;)--?8%(**,(9H%EF!9.,@C=CBA+=!(#+#59
@r7801
TTGCCTCACGATCGCCCCGAAANCACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTG
+
=G$/A3D,C5(72+0761)@<+)D:(C2=-;9D@:(#AB2.48+G$:>G;+6C6)4(BA><40!&(=6F#;,3(3+=,!E,$*:52#855>-=&?%C50+A'3E@@;/5BA%F3/8F!8073B$EHC'0,6'H@#25?.%>.8HA4.?:>G.:<A#68'*F==
@r7802
ACCAATCACCACAACNTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGANA
+
,$.7!9,,1.?1=?)E#7A&*B!#=?'*CA<(D)+-B(G22G@.A<><'.A<%?&@55B/?<?EFB;?D+;0/%&9C:?1!&G-##():%B"-1$#CFF">>%>C+!FE#6B54=EH!/#F7<.)#>C68.G+BC!BH%;F)C9D@>8@(/+-1>/2:<:)C%=32>D;4A'-;"-5<#))<FFF>"2)*,">=77@+;B)3/A6;7,;B/93)(C+H>C+<:,>8D;EF9;9:H<A:@)%1+A65
@r7803
ACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGNGGCTAGATAGTAAA
+
+)*+"!*#&')!%*)%($&##"&$!++++&"#""**#"**!'()*#&'"&$*#(&*$#$)(*&!&"(")%(%*!%+##*'!!
@r7804
ATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGT
+
H8F)G#%C'<CCBF.08')(F,*(>$048-A(;%/0;"D,=2@;?#-HDA
@r7805
NANGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACNTNTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGNTTGCCATCCACCTTATGGCTGCCGCTGTAAATCANCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTACTTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTNGCAAGCAACTGACCT
+
"**(%+"+)"*$+#"$)&&%+)*)*")&+'()#*+)$*#+%+(!*'%*!#+$($%)$)&&++)&*($&!!$!"&!+)*"'%&$#'#'*%!"))#!')'%(&&))'!%$!$)#&"$)!&"")"!'$)"&#)$*!(#)+()!&+"+&(*#)!#%%%*"$*%%'!*+!(#)$$(!(%*((!)'+)((&$$+&$#'(&'$%#)'*#++!&%'#%(""*+&%'"+(+$#)&+!%$*'#'#()!"#"$)#+"$*$+*)%$!'##)&)$)("!!(+!!)&'
@r7806
CTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCT
+
A?4(9,.39&$(7>+&,=7C#B?:8'51B"D6E#9<<CF;32!*3(>.-7;!#(<6<'*0$C(2*@+3;=?2C2)/CG=8D,$!$0=2)6G&2?%5$2/D6&-GAE"*"6
@r7807
AGAGGTGNAGCCGCCACGGGAACGGNTAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGNGATAGC
+
,4?%7A)DC%<)93B);&5-F.3;>G)'C=.;'->?'G:8A2"#*9D0+45<'52'/3?7,#3D$B'2$(4?07%A!:-!53?@4GH-$6(618!#)$E.B=0+5==1".@(6=A=9(>,9&
@r7808
TCTCGTCGTCGTTTCTTCTCTACTGCTTTTTCCGCTTTTTCGCGTNCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTG
+
,4.530CG16#A"7'<;#&&,?*>A%!/D3!<.9@.2/,+1%DA05/+>D?$0*+;C2.*##5A70%-EFH2+-/C80H0&30++5+,0+8'G#)-G:+-,@%>
@r7809
TTCNCCANNAACTCATACATACTAGACAGCCGNTACACCACGTTTTCAGCATGAGAAATTGCNTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAAT
+
('*!!$#&%+%"+''!$*!)&&%*$&&##"(&&!&)&)+""!+&!$('&*"#&'#'#"+))$""*&!''(+!&##*%*&!&(!'!'&'%(+)'"!"*$
@r7810
NNNAGGNNGTCGAAAAATGGGTGGATGGCAGGAAAAANATACTGTGGGACAGCATAAAGCGACGCAATGAGGCACTCGACNGCTTCGTTTATGCGCTG
+
#&(###&!!+)#$(!#&%("')++#*"$)()+(&$*$)+))*+&#&((!$!!&(&(%))#')!('$("!%+$'%&#)+("+##'$+%#$*%&%%$$&(
@r7811
ATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATTGGTTCGG
+
"C268.8#E+%)2'?<<G$C9/E>%,D(>!,#,B!'&//*@8/0D'!-%1)AC?!.A=@A)+9F&=+1F+862H!(E$-A);-H25*+#()0:E?1',E4FH)>H+:;$0,>*-G)#B9E%E?1(#1?%>".)#'$.+!/,/?A/?4<H5&G#477C=
@r7812
AAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATCTTGCGCTAACAGTAGGGAAACTGCGTGTTGAG
+
E$(DC#/&:&%<-G.?9@1$&055:>&0$70C=69580$<%+E::0,<#@(09!%-CG&#*?7D(.=/6.4-G,*427$
@r7813
TACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGNTCCGTTGTGGGGAA
+
EG$A"G.#;;268ED)/A57&(3*1>G@?&5!G.3C37%67+<AA&7D/!@(;#*$+>4?:$-&
@r7814
TGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTNCTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCA
+
>6.!@/;@'6<6&>0+#86')+C#.1+3ED036G7>:0B;*7A)AG:@'E'"/1ED&$5*-!D.H6C7<,?D%0$4!*22*,5-#-74/B,("9$0#G.511((4+3%+"4"0EE6)+26@0+"B%>(A5.H+99>F,>5!0C12@"H"+B::%*0<<1FA&"2#'@&3:)3BH;0<AC?D3!?-)6)7
@r7815
ACTTACATATGGTTCGTGCANACAAACGCAACGAGGCTCTACGCATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATNCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGC
+
:+8></895'3!4@(F43A)3/AG%E>@>'E0#85*-!%1)G44F#&**FGCH86#D;-6$3D!7EB/0+%DE7!<F@&0+/(-<72F1.&E8B+A7C3?,-H00*8+DE&4,69:B7H/6(#F;/():/(.*G);&G4!-9<#.=</1D24*(B*),"F9?8-81!&&*<BG.H?:+F:F,A31AC477$0:*+C!&D>(#=?&!+:9'.'27-*2AC3
@r7816
TACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAA
+
8/2G#)*&)".#?E?9-;88BE'/3F?!+H?DE+0"%F&H&:):!17F80,:@
@r7817
GGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAG
+
+1):1'9!;=3#&11'*9?HH558=!A&=&F.H4G#"*-?";@F4B=AD1;'H!32>B);?*=4/&6A'=%%H%EA+'/(%,?%%B35G:1CE.GG.$B"7)B0)':$0,2!-@=F<719DD/+?@$9)@G.E@@7$5!=/7H7B5:%$7<7;,B&B8'*@-,*-7
@r7818
AGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGAAGCTTAGGCCAAAACAGGNAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAGGCTGGNAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTATACA
+
8.?-%%G0$46,8)(D';8EG$A*(.FG>$2#+3#+G"!BC:.GFF@D-@!7F()96&)+:G/<):0')AFA0A#@29.0!.F5F'$(3#:((?72H'B)?9A!E17F4;)7@;76C<..FE;81H2H,:76E/"AHH70'G1F;@2F5$=*4%9$/;A62?2'%("&">%0-@G7>=$#3:=95;+;E5F:#@<6$/692H6#2$14)2$#599')G(6291CC@/5DH.!63)!(E7E;(F!4)F1?'"992#&-/'A*C<'%86(9A+3B2?*,*H5&F1$&):;86;(C4"F;4EH1B21-$8D3:A$(*%;5"2@1$%@!D5G0C"+6(,@#23B&94&/)6#>FE,%8>2&:A*?@H<F763@/'B(G7*9+6G)A%<92-"=!<0E4?&@(G,!.@!$AC4"'?(.4%D816F#!D$<95-9
@r7819
ATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTCGCCGGACAGGAGCGTAATGT
+
-.=@'//5F2,F=#18%%++BBG'*..>F#1*%,2=#9+!)&1H#C#:$F>8D=D.".;0D,7@A
@r7820
TGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCT
+
,>C$7=6(@=FA-9HHF%#C.923'>.&%E(8C)<-1ED?D=%5+=5>*H>D%@:@A-!E)=G>/.97?;=3")A"8,:E49/(3&$=F@.C?%>
@r7821
NNTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCNTCATTTCAAGCTATTAAATATTGCTAACAGGTATCGT
+
#"*+#&!#+)&+'#')($)#'+)$)"))$'*"(((+&''*$%$&(**+()#'!$+*"*)'**$$$"!"*$"!*+'+$(*)''+%&($'!(+$"#
@r7822
ATGGCGATGTGGCCATCGTCGTGTANTCCTGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACCCAGG
+
+('(+!#&&!""&&"$*'(&'&'$$(&$+##%#"*("("%"+++%+#&%%''#"+!"%#'(#(%((#!&"'+!'%)!$##++#*!#+&+%))!(*"+(('!"
@r7823
GNAACTNNCATANCGCNNNCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACATATGCCCGAGTNAAGATNTTGAGCAAACTTATCGCTNATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCNCAACTCGTGAAAGGTNGGCGGATCCCCTTCGAAGGAAAGAC
+
#!$*#"$#)((!"$!%!%!+$)+#)%!'%!(&)#+#'%+*#!$('#%()%%(++$"+'(%*#&+!%$('+++""!*$&)(*&'+("(*+%%&$#+*+)$!'&!+')#+%'!)'#"%#"+$##*)!!++))($+)**%)&"'(%'*'##*"(*$%(#%'&'+$)"#!*'!#&#%"!!%'+%"&)'*'%"!&%'##*!+!!$#'')#&%+%#$(#$!*$+"(
@r7824
GCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCG
+
E.71D#=F27;,A$?-1C6:AD?#-:C;;80;3':,EHBH4,1*D>(A?6($+#G/5?H,#"(F/5-'=F.7*E1*;
@r7825
GCGTCGCCNGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCT
+
'A'C:;#3D(G.B84'-;H<!C,5++E5>9(26E*D%.*=/(3."1*2*4C'*4<'&0'*0D.3,0A*48,<"0?7#B:$(<$B80C&9%0.=438H>C86H3*:!;C-;"/$'A:**=<?B$<=")1%'
@r7826
TTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCT
+
8"B=.DH2A2E.%A2;*71!,):;.,#'9(F74EE1<;/*
@r7827
AAGTGAGNNATCANTATTGTTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATNAATACAATTGGTTATGTGNTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTG
+
$(*'&*)%#'*%'%!*&)('(+)($$%&+"'+'!*)++$+%*#'*(*()(#)"%&&*))$+$&*&'$%'%"%!*)%"#**%!*#")+*!#"($&)))''!%"*)($)%*'"#!
@r7828
TAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTATGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGC
+
:.-#7$&#7F$A'8-/BC@BH,?H9181@#!:5@$.2+!;#<-2:&A2,;$%%94A%>.<5.C%(3/(;;>!,@8(<ABHH1389C3*C@?7EG1"
@r7829
ACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGNTGATAAATTCACTAAATTGTTTTATGACAATATCCAGAA
+
1-%5,)''H6CG36H%$3<54?(%,5?(:))7:>5$51";A).(B+'3?4F/@0B89#71("!(1;!'>-+0.&:22=G#$"2--D"7;//'F(;":D3A:A=?@70/7!.+<$(""25=<4#9!H4@.3@160?!&6
@r7830
GCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCGTGTTTNGGT
+
(H.?)1!"-D:!@*-4&#92>/G';)'$)$3,E-2%>-B)7'0*"E142>,F#./5F3EB:/D?++59!B0>5@>D@G-$-9;/!'/D-?D!C";8'D:&<#?
@r7831
GTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCNNAATATGTTAATGAGAGAATCGGNATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAGTGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATNAAGATGCAAAACGATAAAGTGCGTTCAGTAATTCAAACCCTTACAG
+
?D!98"%)<;"D9A>40..5:'@@0>-HCB7=!1B:9@94A$CG<D4E35HG?!>$F3E?"$9:9&@E78HD5C632*8)H9#F8DH*=5B%G?9@7#.$6799"6(0701"A$$#8+><2C(.37$?HH)(A&,;161<#('02HB800=BD5+#0$)=(;"<:<3:,E-!+$$8E-D+(((;=$*%>H719*%$!H,&*AF).92>*!!DF=AE$@87$71":0
@r7832
CTTGTGATTGCGCCATACCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCNGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAAT
+
@A@%<"/B'8;1$$@#.GG56@+:D*%5F+9GG6=3E"'/0CC27,CDF+#&!>B%@5,%>H.>DA>,B&F0+()/%)>HF0-?71:9G<"='.-D4>B)EE#$%8A+A:
@r7833
AACCTTCGTAAACACCTCGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATNATTCAGCGCCCGTTCCT
+
+$+&%BE/'<#!<:=3:#5(F#HE0%=%E3;=A()+H"3-/5@0!,3FD*:E-8AAF;ED'G5/:$!;C5D/)C4HF,G>(#A((E''G9E"4!@#5>/('$33GHEF=
@r7834
NNGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAG
+
%!/<1-3>4,":=24DD%-%)D>(/=@:E&2E'*$%*AC15:&24)(7)(@<&)>0F087F:(7B5*6A:"87)3#,H=.8$1&9,E=
@r7835
NCAGNCGNTNTTCGNGACAAANATGATGANCTCAACGGCATTATGG
+
#()#!'#"*&'(#)&)#()$###$!&*""$*))%)&&*+%(*#'#%
@r7836
CCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGTC
+
2C-=G-$G"H?=@)-.H#HH<*<!%=-'$'@.70)45%-'%5*:,CF"@:)90-/'/;00-H,?,/2B,(;(0>.HC<-<>C>;#<?C
@r7837
TTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCT
+
<->+=56,1>2*D%C719F,<GG!E;(+/242<0)4$/1$>F7$'FD+391'0<<($7%B76E?9
@r7838
GATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGNACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGG
+
=4A:/+F0,:=-9*07+.1@B%?-@9%)!.2>396D>5&3H13>A0+$BA9%3D:1B5&'/=,6.$'20->/44&#1;5-)15=<(88HEA1)3D#:G7GG;;$8G&%48/C47F4<@8:746!A=9C>4'$G+.2/A)C-*65#;#,@FG(1G!1(7<.-6E$GAH;0!*1&+A;?H5%>H(<097
@r7839
NCNTANCNGNGTGNNTGCGGACNNCCCNGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACA
+
##"$*"*&'#!)''')%)%#*&#!#&+*"()')&)&&$*"+%#'+*)')!"!)"'$(&$+)$%'!$$(%!$(%$%#$
@r7840
GCTGCTGGTATCTATGACAAGGATCANGCCGAGCGCATTGTCGTAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACNATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGA
+
!"F+#0/>?2-4''28464!>GH)$/4B93-/;"9$?/E3::0@+&<2(,*$?<G91("-"7>8.<B+!2F''0-?D+C<-5/?:572<E':#%?G.5B0H<1(:?-><@'(#>'65C+'B?D3D&-#@%!&?3E@@$+0A269*+'1@F$&#2!9G(2-2
@r7841
GGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCG
+
5D77$H79("C#<%8?)7+AF)2;.B$)++2,(4B!"+F:!B-9D?0H/>E0?$G<H&?'>E7/C9B,4:?#0;&H>)./2
@r7842
ANCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACNCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCCCAATGGCCATT
+
##<#5H0?;D;H4=D-)#;/+??)3B'(2A3D)-;H:#-AD+$:D;>6)<4.9>@9&,1!00#+)6-B$/4-C7$$$!7CC8,%">.=.-"2%3)
@r7843
AGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAA
+
/8F0G3@7%/4E)$63*1D5-:2F-328,.DG"4D$G*53/$2>H?8*13(D:9=8#>4A?H7+038'48D:8B32=,2838@@(EF
@r7844
GNATATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGG
+
'&"+'%"#)($+#)%$*!''!%#+%+)*'##+)""'*(('((+#"##$#+#""$*"($)&%#%&(&$+*&*#
@r7845
TGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTNAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGC
+
B61@.?5#))&#!5,.*,4=@G?&1=2'B972!)*0$89;AC(>5%#919?0=@G$2G.2GB"&7'EGF7':G/>D0E
@r7846
ACNTCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGG
+
')#*+*%*(#(!)((#!$&)%'')'$!#&#&'$#!')(*$&+(!"+(!&%%+!"&!&"##$$)*!"+#(*+%%%!()+!#+!+'"!"!""&#$!*#*#"%!"""!)&$)*)&(!)$&&$$+*#!)*"#(((+'))
@r7847
CTGCATATGTTGTGTTTTACCGTATTATGTAGTCTGTTTTTTATGCGAAATCTAATTTAATATATTGATATTTA
+
>F7)!0%7.C!3!HEF%/8;9,.$;D3."&=HG2DB=:."$8()5B44(E2C51+$77<#DH#-+:FC)71DG.
@r7848
NAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATA
+
%BHD!-,%!A45G:%5G'!;2"=47*=?:1<26#AE7=3;47AA&&#436=*G140-70,<E1H5DA:,6:%-4D9DBG8?/;D/>A)'C7%%D
@r7849
TTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCA
+
73+=H6,;DH-A$*FE!(;765:C*?17C++=(&G0/9(DHDD?"
@r7850
GCATCGGGGCAATCCTTGCGTTTGCAATGGCGTGCCTTCGCGGCAGATATANTGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTNGCCGGACTAAGTAGCAATCTCGCTTATATAAGGAGCGTGTTTATCGGCTACATC
+
?6F@1A9&+0<H</8H;,<-D.7,?<>.GF=*.67B%9:;),(>')252/99:1<7+*H;:=&?A#F)'F"A7!'H5/H&(&>8B&5$!D6;;&',":'0/;,<?<G#A::2@.B<67C$2E9+<G(4/5$!C(.+1<F<E3/".!F>#3<@&B3"=2F"@<*;G>EGA8?GF01>*B-$%@-7F?C)
@r7851
GTAACGGGCAATGGCCTGCGTATCTTCAACAANCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCG
+
F:.':34'3B,3%5$>B4.39!7#*H=#*@H!H6;D+9CCE->'=:6%=771./C6EC"<4H5+3>AH53,3A9<9;=FEG421"'3(:"A&#6?+1'BD#"!;470?';.#>6@@G%@*C7#G/HB#6'F!@)$(;60(@$/@C*+/=5C%8C761.!8:;%F8A&=F!C,!CE"?G=H@9C!!*%?B&F2
@r7852
NCCGTTAAGTTCAATACTACTAATTTTTAGATCGAAAACGTATGTAATAGAGAGTAACTTAAAA
+
*G'5(C:>BH%=?D5H7?!0;:4>-A#9AE;$%*;=BB4>79&G+)&2<>4?H;4:7%E'*/*C
@r7853
NNGTNNGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGANAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATT
+
!$%('#+%"&$*'''"!*("+!(!*#$$*"!#*##&""("(%%#)!#)*"("!*!+"'$+*&*#)"&$(&&!+#++$*%(#!+&"*))+$''+!!$&!!"&%"$
@r7854
CCGTNCCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGTTGTAGCGGAACGGCGCGCCAT
+
*)''$&+&%$)'(#"'(*)+!)++)$!(#""%$'++&$%&%%#&"'#&&(#(*!)&#")%+#!$*"+%(#()&%*('#%!(+*$**%"+)!+%'($
@r7855
CGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTGGTGAGAGATGGACTTTCTCCGTG
+
-,-%<0A.#/C$-H3B0;H7882&E&G)@7E43;'C?H,'F,D/6=F.,2;;7:8E,93"2<30C1=,7F)?!B7"'.$)++9&.*@17CA?D19H))@($7<,1:3
@r7856
ACAACGTTTCTGCGGCATATCGCAAAACGATTACTCCATAACAG
+
(+4;!H$</C'<%=!7H6+%#<>@)G2E=E877&)=%668?8%5
@r7857
NNNNGNNTGNGNNNATNANGCTNANNCNNCNNGANTNANNNNNNTCGNNGGNGTGNNGNANGNATNCCNTGCGNNCGATTNATNTNANGNNACNACAANCGTTTNTNNTCCTNNTATAANNANGNCANNNGTNNCNTTCNCNNNTTGNGCNCCCTANTTGTANGGNNGNCGNTTTNNTGNNCNNNTGGNTNTGNCTGNGGNNGCGCCNNNTGNNGANGCCNCANNNNGGGANGNNGGGNNNNNCNNGCCNNNGNNGGATNT
+
"$!!$!##$$$$#"#"$!"$$$"$"!!#""!#"!#"#$!!#"#$$$"##"!#$#$#!#!!!#$$$"""!!#"#!"!!"#"$$"#!!#!!""$#$"$$!!!$"""""!"!!!#"!"!"!"$$!$##$$#$!$$"!##!!$!"$!!#"!!""!#"#$#"##$#$"$""$"$#$!"$$#"#$""$#!!#$$"#""$#!###!$$!#!!#$!#!"#!!$"#$$#$#$!"#!$$#"!$!!"!"$$$!!$#"!"!""$"$$$#"#$#
@r7858
NTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACC
+
"@.=(";8-<$546H>2:926,!6(*F*(@29'6.GF1.@6>4232941',11#F:
@r7859
TAAGATNAAATAAGAGTAGCCTTTGCCTCGCTATACANTT
+
$+!'##+*%&+**!$"*)##"((&#$)"&+)$($)(&&+$
@r7860
NGCAGACCGGTATGAGGCGGAATATATNCGTCACCTTCACCAATAAATCCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATT
+
!1!;E4"96E!214?9/&<28=EC7+B2".FE84!.ACAB6427A8%G+:?1)$&19FH%8-77HG#&9!8'A8=6)6#3@"21#967?D;.,:"24@$!5C)/*'&*!A'$'(C2>
@r7861
TAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCTAGAAATGACNG
+
;52@F06?:,$3.30%@?-.C:!;;18D-DCC&:)#=/-=,=7+D2=EF"131EF7+B-#&6$;4'@-=!>@8'6H*D1E?1A%
@r7862
GACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTNGA
+
F:D-::-G"=3B=E0#>G8-E##)+@%2*(/*(1:'H5?3F
@r7863
TCNACTNTTNATNAGNTGAAGCCAGGAGAATAACTTATTTAACCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGAATGATACAATATG
+
((%()&!&)"*'!!$"+#+))""+)!*#!#&&"!%&)($%"*%("(&+$'%*)$*+&+#+**&&%$*("())"%(")$%*+$%%$&*+!&+&++!)(
@r7864
NNANTCNNAANNNNANCNAACTGAGGGNGNAANANNAGTNCNGCNGCNNNNTGNNNNNNCATNAGNNANGNTNNGGNGGACNCNNAGGAGNAT
+
!!#"#!"#$#!!$$$!$"$$#!##""#"!#!!$!!$"$"!!!!#!#$$$$#$###$!!"!!#"!$"!"!##""$"!$!##"$$!##!#"#""#
@r7865
ACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCNCGATGCG
+
E>GE2%F-%0::C)$99>@,0%6+)9$4-/&%>*=86.+'5?>8ACE.-%#6;>#+2AE/,81G83GC+)0E':1/E3&>;-.-+D,1G-A
@r7866
CTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTNTCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTA
+
<10?FA.%4+!BD!@<<>1!1(?<.$$H"&%A;A0F+B8H;&8=B#*5565&,*-(*5&2!!=2:<"?"6""5%A'&+82.+DDC>E./+@HH43?;08(8G!4+:*=6/(->1<!G<;'HE"3D.(7#0&8HD2.*7C&6D>9)B%9492E/.1/,0$&(B36&(0.?;?HF8E5-8>3A1AC6!+04467!G2GH+!@?41':
@r7867
CANNACGCCTNNAGNNNGCTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTGCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGT
+
$&"*"'&**'%*%)"&"%"$)++!")#)+%)(&'(#!'&&(!+&)$*+(#'&"%$(#++$$(!#&$$(#))#'"+'!()**"$!)(#+!)&($*""*)"&"*)#$"'*+&('&)!+($(!#(%"$"+"%)(+!(""%+*($$#)'+%!%%!&"'#%(#*)#+%)+!#'%##*
@r7868
CCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTC
+
<*19A#A52HB:2A0:)G9>?HE#@B(@(-:%<:#>?%80-,?G51D
@r7869
CGTCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATG
+
*#<3(A1<6FE*6>DB>3@#871?6!=::E=E<!H%F/3DD)'
@r7870
NNNNATTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATNCGCTGCAGGGCTGACAGTTCAG
+
*#$#(*)('$++"$'(+'%*!#('**!'""()!$+!((''")"*''%)*")&%&("*&+!!+)'$)%#$!+*(+!('&)!*$)*!*+%'"*+*%%*"#""")"
@r7871
CATCTGCGCCNCACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGT
+
0G,57245H@?B#?$=',,*E'9-"B9*B6+>2<D3/?=>:*+<HEG52!),>A.-,7)4)".&)&@45?,!"%:0(AA?:;G2,($.:2<AG.$DF22:>:'!7C5=!.G
@r7872
AAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCA
+
=>F(F,D<=,A-F--(509#%/@'=77*2+@/8#;EC2%GH:B',4'&"?%44#8)C.$0.#H*F2EH+'&;B.#+1H(G5HF#04153;"2C.*"==248)/GBF*4=5>(+;66B3B/;BCD0?.#)#;#;(
@r7873
TACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTG
+
7?9*95-D.7,<*3.)&=%0$7(@.->*#9B793,+20:?%2=
@r7874
ACCTTCTAATCCTATCTGACCATTATAAATTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATTTTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCNAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAA
+
G:>81F>"1B%)B6=*D(G<&(;77+!?G4"815.'36=H"0A(6B)5G%-8!/3D%?4!A@<44>E>852;%?/$6/C,<C*4#&$.;3)47=9&6#-1DB<8*:=10E)E1H-+674FF62*-!23A.53?B0#$"95+<A!3*/+='(BC<F#%!12$)'*&4D51GA:-BDH,"7/.8<@8GDA$E'.+50F2!;3F*EF9G/91"+4+<.&)EE:<"E-D,D-CG54279=DF7+A5/>42%*532C8<H;8*4*09H6?B3/>,+H20-+&.A5+"&=<H2>6"F&F$5*$?E>2(63C4;>'<%583>?@1(-?$$/348>"3(";%?E(-,1@3(%"HF&-(,95G64)A;,">-+0:<2$"%#;@F0.)<9>04D.1//;!+8;)<*D12?'C5'B*H:,$2*&H
@r7875
TGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGATT
+
&)+&(+!"("*)(!+)!(+%#+(#"+)#$+%))'&&&$"*!+"'%'#*+$"'&+!&"'!&#%(&+&""")(&!*$"+"%(
@r7876
GCGCCAGNGGCTGATCACCTCCTGCTCCGGATCGGCGTAACT
+
67,7D0?3165>"CG5)G6.H6!DBAEF7'57G(*$/E'<F1
@r7877
GGCNATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGC
+
$(+)++'%#&"#$)&(*+(*)!("&+"&(**&"$#''&*''+(%$
@r7878
NAATCGANGATNANNCNNNTGTACGNNCTATANNNGNGTGNCCTNGTTNNTTGCNNGNATTGTCGNCNCCGGGANNAANNGCANNGNNNACAANNNGTGNNNNTNAANAGTNNNNN
+
"$!"$$##$$!$$"$#!""##$!"!!!#!"""$#"#!$"!#"#""$!#"#"!"$##!!#$!#"$""!!!""#"###$!#""#""!$!!#$$#!"!$$"$"$!""!$$#"#$$#!##
@r7879
TCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTTGTTTCTCNGTGGAG
+
H9%6#H:A"=%$"3+B=%7(>8#;)FC*?2''?()8"23A!*DE#9H&1<4>/!,;0=A
@r7880
ACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGA
+
@-8/F()@C>.<(8'#D')AFH.1#?*.>5B$8/1"81(31(:B
@r7881
NGATACGTCTGAACTAGCCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCATTTNC
+
5>*.?/*H42CD0*CA<0F)'>#B24.>G(B0&'$>EH*&+(0'<8>+$G54CD%5-9::?-',@:8;9BG$"0):,9=%!:8'
@r7882
ATTGATTCCTCTGCTGGCCAGGATTTTTTCGTGTCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGATTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTA
+
+57C-;@C6"-2$6+>#5(%CCF6),+8:91C1+5*0?/":CC5>DC:7>*F%,334"'=5!8F/GF?;576E#D1-,*D<@+5!4--87C2*G$0<1G?.9?4'DB4$*-$G7)C>>G1:/G+H,&:2F+A4?&<033,6@+6=%5B$A3F"(2:?<4C,+0:;1-:G<*,:6/B.09:%:@H69:7:)!@63"9)0H5(,)9<B""',;8=!'#>:@,:DH%?DE>A>?0(%"!C"F8@$#(A
@r7883
GAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCACAGGAGATTANGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGC
+
,21#4(6C4A=(@<E%H07F:2=+=C)B4,0DFADF'/7A>?<,C?2923"3'342&$H?<9*5EB+H:-8739;A<5;,#0C@?+&)D)=9B?./A?#8,GG5E39:C(->:H)"!,C<:$8F81-F5*%4@:G#)EC!%3(#))(H1
@r7884
NCNGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGNATACGGGNAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGC
+
'))$+%!+%")#$("&")%++((!$#*%%!)#$("#(()&$+!%"#*$%#%(*!)$+%'#*#!$#$(+!))'&#'!*#%*+&#(%*""(!"((%#"(*!"%($(!"&++*(#$&$$+*"!#)$!&('&(+&)+"'"('+'+$$$'($+&%*+*'!**+$(""&)!&"+'%(&$+#%'*#&(*")*)+))"$+*#)&
@r7885
CTGANTGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTC
+
G@%F%E<11-"C,5EE=%#<?%"&1AGF*;5E,D;2,,B*3@G<&CH'5;A<)':;=3
@r7886
GGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCG
+
A!*'A6BEC3/)E'9C>"GHECF5E:"A"&007GC!(DG24*6
@r7887
GATTGGTNTCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTT
+
GG6)F-D@">*+@3+&5=?E("BD%BC6,GB:*/7725"9('69C-6:7"E='E674-=1='1",!!/?0C07>=8*/&="B'B)B@HB*ED;)*",-,<H0;;D/0>(((1
@r7888
CTAGATGAAGAGCAAGNGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATCTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGA
+
,8*=F29F#+EC9BG7?A70D4>%590"=B$'0:C!H;5B.3)';65+H1'+C7:3B(#5"":7/7A:@="FDB42*B1)5,'7',?/C+=.-@B3)#&F'AC$69@;+8<//:)(*?;5E!5.3-+*(!34-566>#;E=;ED;,A%'&,37FC6C)!5(7'=-:1:-;81"
@r7889
GTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGNGGTTTTGTCATTTATGGAGCG
+
;#<B7@&24(.+!*A*/7+B5AD"3@416'3#!H.;=%8%-'(+5@7H'EB5:,(E;E'(8'
@r7890
NAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGNGGTATGACCATCACCGTGAA
+
)+"#*#"$*!)"#"*!'("'*!+'#$*#$)!#&+$"%*&)))$$##%&%%(+%*%&('&$%*'%")$""!%(($+*(+&&*))#!($++
@r7891
CTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAAT
+
9C56-431!7202F#+5(C'84*H/+3CC>9,5C0H#!=7<'G'/'/>8:"70E;4!2D/-&9>5/H3>C.5##"8BH.$%HH1--65!<BC=&4*G$=;A4E*C/B;)@=?>H&A8>13G5=?*:83+4>E>CG<$C%8F9-5&.-H7,.G>-D<+.26C0A!)8<?B!/.5+B*-#)GD&@F@HD(@''%$+/C
@r7892
TNTTTACAACCNCTAAACCCTCAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGNCTGATCGTCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATNAGGGGCATTTTCACTCC
+
)%(&#*('")##)#*&(('#"(+&&+"!'"&)"+#$'&!(%*%*&$%)$+*%&(+$!##!!%''&(&'"*#'*%'!(!&'%%(#+$!#'*#$+$)!!)')$'"!&('((*&!*!!"'%#'')!)*+%'*%%!&)(#$))&")%&("($*)+&""%+"'!("#(#"#%)"'$#*&()"$'$*(%"#$'
@r7893
GCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAANGTTTTTCCATCGAT
+
,26B;&B-BH3G?&$=9-593$!8/(A-B/A,B'9F385)5@D+>;<FC;77.38&9=7>1A4BG(>.>88#6=139D832A*,(A8160.!C>)0H>5
@r7894
TGCGTCGCTGCCATTTGTCNGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCAT
+
-@1#*7*E);89G6-9+;*A<=C-C@4&B<:6<,1H#C30EG81/$@82"=;;,3:<?6;0G:1#2DB5."'DFAC=-(,%63F+B.<F69@9/2!/891@DBE(1D;HB31DD-=25<#+!9HAA5C1&=CC(#'%6*C9D=D/6F'"D1@1>54F'9/@27-"&:@(#%("?A-D?.*/89#H7"/6&$#963&&<%&G85'4B'*H(;77:2?=?;;%<=!B)3&G>6&<6;+6G)5'@-*@C89-<
@r7895
CGTCTTCCNAAAGAGCTGGNCTATGCGCTGCAGCATCAACTGAGGNTGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGT
+
*?F6E2F2B,@B61?F+E,2(#H)A/:/#.G)>%C&+F(;-*$;('1+/-2-)?!%+'>7"D!&EBCB/D5=)+!8C@F:>)&/$4D$
@r7896
TCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGT
+
H'=<'"?=D53$4<8B@A:8=AE(5:G<EB35>>(&?=%.72A;71#>&1%%-1
@r7897
GGAAGAACGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAA
+
D,@?.@'%&8?"?EC*;:23=++637F9D315B"%"CBE9/0:$,?+:1,<C?'EGCE&F&+7?A!D$)53:9206=((%6,-
@r7898
ATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTT
+
<*=<*@3BE>,(+6)9;,E7/H&B@,%<)E8+2BE9"<!!*8#@(76?:3@,!G)>A>!-#''(F.
@r7899
CCTGCNTTAGCAAGATTTNCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGANGCGTGTTTCTTGAGAATTTAACATTTACAACCTTT
+
A<AD/-%=7%)G#??!")#+1@B92'@862,"E(;3+,??G:=8@9&B5??BD)!A3=/@('8D)GB)'D&3/?E2*)+D6"'&">725"?09#.A0!*#<>9;.25C6;!*)G10"
@r7900
AGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCT
+
B',7G#7=%3C+9HB%79*#<,#'(08#%??,#7;+/><'5=
@r7901
TTAAGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCC
+
6)=H)4(#.>*-:(/?5.8;)CA>?'4$9<>$1F)#/04;-:/EB":*A%BB+*B
@r7902
TGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCG
+
(A*"3'<E5-+!2E-&()*431C?-14)?';)$'&0</638EG(B4'.B!/@)!9!@6>C-+#F29H&+AEE3$G';$HBAB".'
@r7903
TNNATCACNNNNTTGGTACGGANACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGANGTTCTTTTT
+
"#!(&!'&#"&!%%!%(+'''$()"*"!)*"#"!!$+""+&*$("(%*'#)$**'$$*#!'&#&$%!!""(*"")''*#!+!$!"%*%")*)+#()*%#&!%#$!(*(*(($%*"!+!#$++###$$'(+#%")%+)*&(+"(%%%%#(##*""$&$&&$"(&')"##*+(%&)+##(&%)&#!*++$')*!'+(*(!#+(()''##$'&!!'!"#**"&""!)%&"$)*()+$"+"*+!$(%&
@r7904
GATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACNGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTAC
+
-,-65>/2D48)G697+0,'38H3$:6-HG%3GC/#;?76/.H/@+A*%5/8?;?&;0-;@=&1!<!H,D'6:EA@19.=(A9E@%,8($/'?B3F1+-5G'%07;1-;1,<=8$6*@C(63;31C$%#<5;2>4311$.9"GE%2=$7437:'@,?6+!A(;F*:2/8"A'#<B1!B$>1C$E*+1??F8953DDF>$"81G*B26/7C)#A"'1#2(,3%!7:*BC21546--F*6'80)F'@!.!H-FDA:69H;@"G*:@E!>+"253!@G*=*1'.7&B0@"#>(#-H4)9!3.'"$98H+7/'4>?6)B+3=>B@%$5"89"/,.>%%(=/-#B3B54?:9
@r7905
GGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTA
+
*,8-'G;;(7$'$#C9*5.*"@"015(>=2*;0<6:C/"?@B
@r7906
GTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTC
+
(&G8C*;.)H-D(5-8=B!&&E$H-<=(7$;F+2'@9842"G&;;@%9E!$!#>#*#'=40/%(AF)>HF*6$?G!H91C-<7$
@r7907
TGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGC
+
&'1,H/<B'3H7?@E?,8-'>"@87"-9($<63.8<(?@!&@
@r7908
NCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTC
+
$*+)"*$+!)!#))"'+*!!("'(#(+'('!("#(*$!!+%+"(()(+#
@r7909
AGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGG
+
*G$@27F':4@76@%A"5994FGD$'$E#.+9;<5CA6#HA5.E0)H,5CG=:5H(#
@r7910
AATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCAC
+
E7AFD).+->A"E=4#6@.4+,)*")F-;-GF1EH/+;4#F!$$*9F$,:H?:D=1:?%=AE'?'<!02!,23>."70
@r7911
ACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATNAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCA
+
CH;:"A(#500%;>0)7)G'*;+"A<*"(>"+50/:A0>:%A2":9+7E@;5%5:+H%1B(&6>=BF@7#:4&'63E3E&(&@GD89'92;E:/&E!(;>>DE+&;('<D9F30314C63C83>$@)C7@/$&%2D=%.641A69&A%307>3!"D'-9*F&-FE.8<,5?(0/EB$8=D#B+"-;?)//!FE,F%)<G*)$;6-0)$G
@r7912
CTAAAGCTGATAATGATGCTCTGCGTGATGATGTNGCCGCTGGTCGTCGT
+
:$GFC#$:8F&!/DD/"!8?%$1;*#D@?(A"'$)@9*BH37HF#C;9/G
@r7913
TTTGCTGGCTGTCACNCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCTGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGC
+
&.@C$BGH<@9A>GAB(7,.%$>E0(;<-B7A8*(C0F7?FC,H8,08=-@+B87(,&3,$&8=39-+C:('!#D"7#%4?E3--":*#4E0F9F4>-BF=7#)%E94>"D02E1+7.1E/G8*H!4:#)6/5D@G1'&,1FH0#*3#E9-A%'C.,CG88A?>3*3&=DG:3BC#:<,90$=<<7<%.22'#8(7/'/&>:6H>A#+<'!'A&<,7@66$,&F3
@r7914
TCANCACCNGNNGTGNCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACNTTAAGTTATGACGAAGACGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAANACCCGCGAGGTGGCCGCCCGTCACTGCAGCCAGCGGGGAATATCAGGTGCTGGCGCGATAGGACACACCGAAGGTGGTGAAGGG
+
(')!*)(*"$)#%*!%+&$*$$)*%"$*)&)'(*###$%&""%+"&#'"!*$&&'"%%)+$*"+"&&'#"*+%+(!))*$&"#&!'$((#+)"$*"($#+%"(""")!"+*)!++#((**$("#$%&"%"#(("#%)('$)(())$&&#&$+%+'!+#"+'!!)#%*'&*($%((+*+***('&+"!""&%!+!#%
@r7915
ATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGG
+
'B:-4<:'.!6H#0873&@'%D94'59H%"9@D"0!E+;E!0-+C8E:$5B::4E17?FC-E"E.#%G3:&A='<0@?A)195*@>B-&4%<5&7>B/E>0A94<6@-9<43G3>)*G.B6.BGE*;?C8;9*?!&5A;F?.C-!7=+0,@171(2,+143(>"#15,14!D7=0!=BB20/CE+>)<0?!
@r7916
GACATCTACTAATCTTGTGATAGTAAATAAAACAATTNCATGTCCAGAGCTCATTNGAAGCAGATATTNCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAG
+
G$,4'C@.:=;=6-7<C$=+#(0.39G9AD%:D55%*8A0=)*)F/;$@E'*D/*?<4*%=2.F7#A<.@'*%D)??A(<37+ED;A*?'(A8(*@'H."2#BC=6C@++;+52<#G#>0!66)67**'@!<)&>,,6!3)CH:$,:F##?@'#:8"4;D0=H@4+5;7,D3.=CE<BE@C%5;1H%)+,2;'5,$0!BBC/.A=4:.4>/8D9*
@r7917
TNTATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTNAATGACCCAGGCTGAGAAANTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTNAGGAAAGCGGATGNTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACNCAATATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGT
+
&'!++)$)"!)%!)"*)&+*+)"#'%*+'!%%'")*'$$"$$'+#*++"("(%%$++%(&*+*&'')&#%%&!%(!&)+&*%**($%(*$'%$%*%!$!$'*&)#)$$*)$""')*$'&#$)"'%&+#!'%"+!"%&*##'"$%&"%+)#*%&!))+'!!&$$*#*&*#"%'%*$+(!&*"""#$!%$+%##')'!'%+"")$)'+(&*(%!'"")"##&*#)$'+####%"+%*(!%!+"'%)$)(%'#+%%)*+*+!%##(&&$+)*!!!#(')")#%+"%(&+#+(&!'+()"#((%&&"*%)&'$"$%(("(!)('+
@r7918
TTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGATGAGGTTCCCATGTACCCGCGTATCGTT
+
4B!H9>/>;$!;&<'<=9;1$:E+7B26',-)-:A7583B>=&3<F39=8-@B2<*/78G!B!"+C#;2=G-A$'&9,=9)5&1&D+E#*0<?
@r7919
GGAGAGCCATTCAACAGAGTTATNGAAGCGGAGAACATCAACGACTGCTACGACCACTNGATGATATGGGCGCAGATAGCACATGCAG
+
:F#-$?@)7G0#D%2*68'7+F;B9>081:*$=11&F-:G7)AGH:./)2=88HE>'!GH0;+4*?52-C#/+:8!:554'B6>@=(<
@r7920
GCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATNAGAT
+
:*@36@&:8A!)0F2G49C3:!(/23A-<)575$/F3F##C:FG:9)"*9!##3E(F'/#(F>%'-#.B:4*H.@807EFE5$/7+.87*")8@8C'49G;>$
@r7921
AGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCNGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTC
+
$F-.;0%;-45;:#2!;95=+,#.F97)+&/%.-<75&!'!-@2G?50),"(E0>*"<!!D2<+"8,"(43;!:$0#"3>$@.0C/47CH;">9E2")A6/E9%-;!2<AE/@#G+AF-;@(+C:5
@r7922
TTATTGCNGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCG
+
%++'$&')+%!%(()'$!(#%#&&&')!#*$(")$#$""('%##+*()
@r7923
TGCTGAAACGTGGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGNAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCCACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAA
+
*'9?GCG2H,!:-$+*(.<G@H)<1$%*(%,8G3@>B?E4,)B#7#%'>H?-E'EE%:;$&C9/65;2AE$?&*GC?@2%(:E&6C$$-BF.5?=C175,</>*0B4#8@>@-1A'!!G5DHH!F-ACBB@'!3;(?8/92'E?9"2*/.EC)D#6F'*4F7D/(%(5,?64+8&G/4"224H"09=FG$"*'=*=/G3B/#'7D>%)<9%>4:.;,,)
@r7924
CAATTATGACGCAGGTATATTGCGTATTAANTGATCTGCATCAACTTAACGTAAANACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGT
+
3.8020B71FC-F?;9%%.E9"&/=#%8#>H="F$C5B+F0@0&H=":E3EC*?)'27-)&2*#@5/,G&+"C(3$;C)F<CG&(#4H>$42:6"&B6%4(*B>7C<@B)36;#+!5(,#2>BBB**7':$#0$G&1*+D4@C%A5'<1*?HB22?&H)GC2A27B+/D8<DD("-*-<%9(F2@.5)&).8*3*E8!129G#,F,#:(!8$8(%9-51D!>.6<,
@r7925
ATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACNTTC
+
0%AA&4(<77%30H,7@&3)'C'<B,.FD1C8@GE5&=>$$<
@r7926
GTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGNCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTAATAGGTTGCATGCTAGATGCTGATATATTTTAGAGG
+
7G:H)(?4520+91;=GC;26'@)/@F+=<@%&5=F6G$3FG0E.D:B94BA4>F@7?2H%/#7&>D%;3@$13/=9@>E87FF6<G).0>$,2>?"H!+?-(-C?F7?B)','/6%<,A
@r7927
CGGNANCAGATTNCNGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGC
+
)(#!**#)&$*"&%"+**+&%&$#'**&"#%$$!'!"*&)!+'*+(#)&*))!$$*(#'"%"'&"'+*!($#("$)'#)&#)#$!$$(+$+%#"($('$)+*)++*
@r7928
GTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATNAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAANCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCNGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGNGGTGTACCGGCTGTCTGGTATGTATGAGTNTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCNNGCCCGCAGACAGCCT
+
7!12@66D17%8A!5#F9!'EH&8<5=1"G%DGB96%19@@7'82CH%HC3!@<47$H4#H15&=4H=2*B$"G"3!4<<>8.0;2!(A;!'0G!:7H"<;>*4+.A4G*%)/A6!?38!:!AH/)>+(0/78*><F@89&F95)3-(75),5946(.G%1)+)*42D1))G9C4C=(E1644,C7-*=7$;,3D<7837*?=B<1&=?*&*G&E;%84#+54:4E))G'?*BH=##<@1(6"%/02;@!E@H:F)0>22)748-.6)/7.8:?&4GH:5E(71C>9"600&+.'91($<<F%.?5&GD:(+BC/$C/=5BE4))>=$6(?#7.))32$5+(-#5#A!E,AF%5-#03
@r7929
CTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTNCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTC
+
5#5:<0:F,5!@G?B*39%@0;3,HC%"5=/.0D!88D?>!9&>")/$A9%<C#2)F!)**!2)%+8,!?A6#0!;4!3.>*3,=#4?-5.4G8@''52E'-A17(;$/C60+B<#4.@H24<!7>1;+2>6F):7E%"D.A79863E<)'""#/DD&AH3*&=<A>3>:CGA9(D>=#(3H4@;,?3@1/G:0<A+%+6&?%,"A:H"ED'=
@r7930
TGATCCGGCAATGGCGNCAGCCCCCANGACAATCTGGAATACGCCACCTGACTTGGCCNCGGCGACTCTGGGAACTA
+
E?!?)5.G<:3A?&;.+C2G6:76;4*:.D*!$G#,4@$*'C?+8C</,4GHH:?5D#E>&;=?).)71H&CFA8C>
@r7931
TAAAGATCTCGGCGTATATCAAAGCGCGATCACCAAGGCCATTNATGCAGGCCGAAAGATTTTGTTAACTATAAACG
+
=9&4*E@DG:E+*9'1!52??!D"3H>+<8008=*=)'80<6).C4?A-D>G42:4:2.DA<6<0.;)3F1E>*-B0
@r7932
TGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGT
+
'C&1):7HC-5A2$<C'>68$(E5F98).EC5>D=F+C,<8@A#3D911E59!?6(''@09*
@r7933
TNNGCCGNGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGGGCTTA
+
%&!(+('%('''%'*%*(%$%)+"#+%"*"+""&'**!)+""*%#()%%%+'(*!++''&%!*)+'#+!)&"(%*+&!!)!!
@r7934
GTCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGNGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCCGATGATTCCGGTCCTTGCGATAAA
+
"'"&#%*+)++%+!#+"!+#%)%)$"&*))+&%+(!%"%%")"&*#"+&&((()+%$)++$&')&"%&*%!$&(!+'$$!#$(++$*#)$%#&&+)#!')!'!(&#%(+(*"%'%"#$)#!)!&*&#
@r7935
TTCCANGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAAC
+
%<H:6C2=>B(BA!=88'7>$6F='<B,-E+B;,-#($$A*B+$$-C2#,H8%@,6(EE$$#!>)C0=H-"="G<(98<1>H'#371-9;'FH?>,9'29?2#=84</H$A!8@H6!>"?F.>>/=!FA1$<B8FG2
@r7936
GCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAA
+
9A9DG=1#7+9+1?";EC:!E1B+?4FF$43'D%?*7@-?3=*03#!.4(*'0;G5C2;24E80:H<"0&"?27G@(@3E*B/)<AF#?<-GH;,87?E!H
@r7937
ATGCCATTCTGCNTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTNTACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTAC
+
&'04(.DF&E#6*E*)EH5D6,?0.E36?3H%G6+4(,?46$@0$/6;2%*2>E-"/!A7/.+=17:)";=:,)?0C-3:*@G;D&'/@.E2=@#$8*DF@$)"FDFGC)AB/4=*CCG;G0&#3B*/+&+!>!!@?"*9?0"@&)-'7H1')!):8F%G=7<AF1;*>/-1:(*1B:HA>%?&/!'+/)+/)/.?*HB?4H?-#GC4'&3)6:D&"1<,3%(=AC)::E5-1:C))96.&'9#8$B-@05@6/6)1*,1+)E"7&64*%>(E-82#G
@r7938
AAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGACGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTT
+
:#G6:DC/)352#;A&24D4,H/3;1G;HH:D%H/".'19(.6(..',;D7E<;C&"&>.#:'?84.FFG+84C3F-@2D)C++A8BA.HF78B*)+!A=2@%DDH'H478C9)9'=:39(8B
@r7939
GTACCNGTAAAACAACTTCCTGTCATGGGCGGTAGATCTCTAAATCGTGCNCAGGCTCTNGCGAAGATCGCAGAAATCAAAGCTNAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCANCAGTAACCAGCATAAATCAGGCCGCGGCTAAAATG
+
&(*'(!'+!*$&#$&#&"'**#$"&%*)*!!!%$")#(&%&)#+'**%&$)'#&$+&())'$+#%%)**$*%!*&%+('+'**('*#$!&#+'"%("#&#+"#%%&*+*"&#(+&&**#&""(()%*##%%%%#))(($%!!%)&(''&")&'+(!#*"+!*)+*(#%!%()##$%#)"&$#%!&"'!%#$$$!$+!#!"&"#+#&(*"$($"+&!*!%%"("'$'%(+!
@r7940
ATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTT
+
9"2(6>?%'.2-<&@><,-068>*4.B82)!0$A+93#+9G5;(?8$&>>E1"&=4!#%2;7>=*F*7*$/<*2(3%HG'6>
@r7941
CACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGC
+
F/#B6!<"<);"E0,"#C=!A#:'#9=@B.>B"&7956D@F;?38G:5&6,+*.2G.-C'.(B-$$"!$(@GD(?B4"G5@#'7<$050$EB24F-.8"?=>C'1'0-<
@r7942
NGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCAT
+
%H0;6<+9+F?HF7B?G=<'.D-"4%&,(!E=F=?=9;9>EE+H(60.E692"0<7/)7%67A$B51,-<6"5A*'.,E/""!5:?@H13.C4"6&1.7)FCDHH/(;F'DBG*5)AF8)(=-;%=>4D#8-&!'G'"H%+7!$8(2H'>8,CA41D*>(.1)?/)&,@(22A*&!0,GC
@r7943
TCATTGCAAAGATCAAACAACTTGTATTACATTGACAGNTAAGCAGTTNATTTTATCACCTCTAAANNATATCAGCATCTAGCATGCAACCTATCAAAATGGA
+
(@6F&H.7":26!00<C:7>1(F*D6.=#>$B?3#)1$0%"%@18<>6&+42HC8C&-B0D-BA82"56DD2.22@:.668#2C!C+47%'6#7.E&E>EF9!
@r7944
CAGATGTCGACTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTNAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGG
+
&>#F0(;9CC9#,E&=!F+!:G'#&(&7F*4H<5?1FB@/C9&4%17,3B7D!B!<695/$).,46:*(H=#HAE,HC'$3>4%C&1"FD.0"A5C61EF7H"4$36>=<6/00#=@!14A?ED)%66B+%&C/F&?(DBA?5($1?/H-4=+/6#%'E-AC?2#B+<@),
@r7945
GACACGGATGAAACTGCCGGTNAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTC
+
B'G%&4?+B)7/3H'!!%6&(86A-59$%'*-9C1&#D3(;$(7@29<!70A(=BD%-8<-E,#8*?=).%1,#D=.,:7#40/?$AH&81E124(-!E+//H(:,G<E-)&,$CF=$&/#A02.&BC*
@r7946
TATCCCTTTGGGATTCTTGACTCGATANGNCTATTATTTTCAGAGAAAANA
+
F3.C=@D(0.&:#(H"8D$%<HD##6.!*9@+!5F<&E2F4G()D:C5!@$
@r7947
CGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGCGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGANCCGCAGAATCTGGCGGACCCGGCTNACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCACGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAA
+
+3(:*A2A%2"G#H)!.D<D%H$71-)A&/8.(DBGE21*9=.*'0E'>6<4:*BG4BE-?;=0<FE!<C>HF6!1/G(<'CHA+?=F8=!)'H9-::A$.$+!#3=$,:-G59@C44="+%;7,//*9B(2'/>?@F*8DFH/':*>B,92@,5*&"049'4.3+=:0B:B*18/./$11*7F24?=5B'9->'E&BC";:?G34.+$;01705!3><"H2<$E7;:
@r7948
TGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACA
+
3(!;9=#9-'1+#47',@:2;*!2G?$?5=?CED<,"0/=
@r7949
GACATAAATCATCAACAAAACNCAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAAT
+
>!D<6;--;!B%5G.A?,C(#=F4EG=35DH0#?*(1!8$G?"..!?&!+HD,/$3"EE&/2
@r7950
GNAAGCGGGTCGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTNTATCAGTAATCGACCTTAN
+
'%(==E2H26H"E1;;/D*8.44*=')@)4(DB@C9--)#)5H-$F7F(<#96F,G*&<%@*5A4!$G+/(9D14$4,(H*HH>GF$G<(;E)1!'C'%+)H@/#=B2$B@4"FB@8H7G,&H.
@r7951
ATGATGACCGTNCTCAAACATCGGGTTGAGTATTATCTTACTGTTCCTTTACATAAA
+
5/@%F:+11E*A=F<H&$+/B"'=2@37"6C6C'2"/:721/2-4F*:37=2;8D.+
@r7952
CCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGTCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGT
+
#>.7-*6B/;=;!;"84.A3>3";":4B(5A#HC4F.-.8!(-D32H.D#;;AA;0?H!*B1G-1?0"F17%=""1?'-(:=&9&.70@)G#&+785CE(4-$D4/83".;D@6.EC1779+(@:%?,
@r7953
GAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTNATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTT
+
71:B6+,"60>A0!F/%6?1;9"$C*1+!D(*!"-:592FG:=6@%#628<<!3G6#)D*)A?91D:!75A!/,4-$7D*%>,5)&5+H#!FB=$*(7,#2?%A!0(!-E7%#3&D#26!2'/-GD25?B-=&--#9/
@r7954
CTTCCCGAATNACCCGNATATTTTTGATCTGACCGAATCGCAGCAGNTGACTGCTGAAGAGCAGGTCGAAAA
+
::A"!-C5=%8&<76<C95/>-E8).!'*89)8DB5"!*2#*6?E><060;+?#;AED/F3!-@=$CG(9@<
@r7955
AAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTT
+
FGA&-%/4#)=@"*:%,)7(?=+#"3"&DF+G'D*/0G&+HC;(D:$&-),H6=57)!(:01GG1G;D!2F>+=6FA7(%-F;
@r7956
TCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACG
+
38@<)*1H=.5AC"*%8::'+FA>/9C??BG6H4$-E1>1;88.#%&0-&9'9D;3+=38::<0*)>&<(972*
@r7957
ACTTGCGGTGACAGTCACTCCGGCCNGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCNGGGATACCGGTGTGAGTCATCTGAAAGGGA
+
+$*+%($#'##"#('+*!*$(&(+($($+*$)&%'$)!)("$)%+"#)+%+#!("(()()+)!"$)#"(%*%)(#'$$#$!'$$$"%#"+&$#+!"'$*&'$)+*!(+!+!%#)(&)(!"))%(+%#'+$!&("
@r7958
ATTCCGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTC
+
;##A=+>=:G0A+903;1A1A*C)3.)?@=!:37>(?4;FG(9+'H#9$.7E%(+1?D=9G
@r7959
AAACTGCNGGTTTTCNTTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAANGATGCCATTCTGCTTATCAGGAAAGGCGTAAANTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAG
+
C:.G48.2B$!#&H+A!E0$?"(10>H-1=9;265218((:"EF!5A"*8$B@<*.<GE5#=?FG.=D!@/06FB<7;B<F,99+&2+>$3>@(1>=3/*=H@:5%&$$,1B)5A$.H/77AF>54GAG5,H6/)
@r7960
CGGCGGGCCTGGTTAGCCANTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCNAATGCGTAC
+
@2(2,=?1D-F<4F(0,?;<F#F,B9&2B3@9"%;4*E74B',;&9#A9/A,<$:?D60=@)5"-F;@!/A7,#>.ADC#D$9!
@r7961
AGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATNTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGA
+
/)0492D"BA#1!;+.";G(:-#4A0,13/(B;CH71BAEE,#!4*$-,"C>986=@E!H2DHA$-2,/AH*@4#8B@<
@r7962
AGGTTCGCTTTGGTGATGGCTATTCTCAGCGAGCGCTTGCCGGGCTGAATG
+
<*3D@<E:48:71'4D=(,E,3>H@71;4G/4B?G:H!'5)&?@14830*6
@r7963
TGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACG
+
&.23B/(DB81>)!<1+%==&%;;?)<*<'C-!F/3''8'$C=0E61>2:=79G$?.!(#;-4F+6:3>2,/4%D,6!@%;&2.4@=;E561+:':/)"1/!)=4E)HH8,$<'=,A@8%",2,,<$D18&@<-:3!!!531)H5DB3DH!%B!3-9#FD<C#9+A/E$>@-7!$!507%749&#>6+
@r7964
CCAAAACTTGCTGTCGCGTATCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAANTCGCACACCCACAGTG
+
.+?4/)@!A2!7>&E-2%:2/)!0#F+E@920@D?B/:CB9>EB@<>"51D?CB)4E:!+;35G>=A);A65)23#B*1:5)5/@.=8);A@(G;F%*7<B1%8>=7.7#!#92G&3"!-B*CD
@r7965
ACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCAT
+
+*!("&)")%(%"#&&!$%##&%(!'*&+'**+)&%(%&"*+'(&!)+
@r7966
GGGGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGC
+
##.1C/GG@0E9.E/2)3109!@F(7G<F<@0D@D)G$G:(&G
@r7967
GAGTGGCAGATATAGCCTGGTGGTTCANGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTGCTGCTGAATCAATGATGTCTGCCATCTTTCANTAATCCCNGNACTGTTGGTTAATACGCTTGAGGATGAATGNGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGA
+
?G=(<"(&!#D9)3<-?=0<$9+GD<>3@"</+%/*DD'FF0D2'(>F.;")+67<;3$/529$;A2.?1'462F?@;0%4<&51A<11"1/2$0*C8$/CD,(@@92<F=3294..0-/6.F5#H%A,'=638,!'=C3(B.)FC9"G$72C"CE<F(=H5'GHB2<D%)6*C$/$>D#E>2#:0B8'!=+;7:*%2?D'F)!*CF!/2B);(A#25%?A2332AC3!,;%;C?"?B50B<@&,?C-B8:E-<?CE
@r7968
TTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTT
+
:;@,5!H:!0>'D3D2+-CF0AE/G0B*FB,3#$B+#;!=2>FA&,;E!7-6'&,'#D7E6A(#628?.B@+GD0C=#2&0'A,HG:=$.$0C:91$&9$;?0&F:DF(&/E)3A!C?/.@E8)
@r7969
NGGNNTNATCTCAATANTATATGGATCATAGCTGGCAACTAATTCAGTNCAGTAAATATCCTCAATAGGGAAT
+
"%'&#*"$(+"!#(#("(+!%*$#()###%!"#('*)#&&**%!"&$'"!$"++)'+()'!**!((*()*+*!
@r7970
TCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATGAATGATGTATTTTTTGATGTTTGA
+
C".+7$,F&12;'!0*0*$GH&,?%4@@:..8@GA:544"AB?>'7-B<23;6(4.."F.=*?7%,-"F<=/"67.B@?!
@r7971
NTTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTTCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTNGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCT
+
#(,.;,D:E5/3$;!+/B8/?H"B0,&%8C6<7,A7%*#D&.&'$+C-(4(D::)06D:=*54(00/.(C/@/1CE#C$9>A?!")"+E671!8%H2(922#(277/B)G>58BG2091>E.%#=E?%55-*/E%%
@r7972
AACGGAATTATCACTGTTGATNCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGC
+
-#DA.03(!.H,86C6#;B!H)H52;1,.&##!D4/5%0/D%?A='%0>:+.F09)%;1:/8').H;2?F@4A*(6<1G?56)$G,,2%"$>0:C"94)6
@r7973
CTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTT
+
4F-31;)";(9%10F>8#2?E"31<;<<D6H2>F57:>,3%$-,"D&4E?"",D!)-
@r7974
GCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACNTTAGTGAGTTNATTGAGCTTGGTGTGTT
+
=-(&;5B5(@7D8)/1<FA''4&>!C<?=F&<&1!CC1:0='$1+!H8-3(A&*#A&'!H!(<>0E1
@r7975
GTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTT
+
==H(&7>..:D0@?"<A/=38EFCH@,'GA&-3$$)7'*B#9@F3>268&C'#/G1D)9>8/E20,9E420=@*<.
@r7976
TTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAA
+
3:!=)H"+@EFC)+=F/.>+#;A4*?!+A80&%HH5A?6/7A'0"3"&AC'8*!#A!*870D$1("2"%&FH=9:AH'%)?2B9<-)@:=,:
@r7977
TACATTCATNGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAATTTACATGAGCAAAATTAAAGCAATAA
+
&"776(1A7G*947.!AD,H*&?@1)-,)<$6603)7C<39;DG'<-)0D=E(C749EE:+=*?43.$!%?D=6($+*;B&G"?:</#9$-"'+DC
@r7978
ACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCG
+
%4<%/-$H%$&9((<42>H'+:?C9*#G;E2>%7/*$C?,(:+/F9"2<)*9(<@2@,>4<%78F:%#!?>>?/F6+
@r7979
AACTGAAGAATGCCGGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCG
+
:?-6<G<-&(#G,5:-%,+BH:3=<;.F8?-%D&18G=+A>'("//;0;>0F@'<)B">#H@9E3;3
@r7980
TTACANAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGACTTGTGGCTTGGCTCTGCTAACACNTTGCTCATAGGAGATATGGTA
+
,"'664)B(@8@*'"=5HH<*9!!;:A4?7,$:14/0@(&19C%B23(4A7;371"4,,G@9BG1=";H0+:*181E'#"C1%;7&""%8'?<0&)5E$G6
@r7981
AGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGTTGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATC
+
!+:97%7D6>#E?.B3A;C<<@7<#HB82>:6'8/#/#+49?<-.9=;;$C1/C><77@G;47*,%DE;)3)3>;D+'2?5-CH?)'3(!5BA>5BF$4;608/0F--8B0(+:$HCB.*9@"D1G6B9'B?6&#B@.:$*2A?488<?187D>9=9(,5C6/9%1HD#C?"<;?(*(>:-/6-/*D=,2@-71>!?F!7*A>@#)%*18!(=@!:>(BHE5#"@)29?"F'F9,#)'?+
@r7982
CGAAGAGCATCCTCAGGATGTGATGGAANAATACCAGGACTATCCTTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGNTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGAGAAATGGGCAATACGAACGTCGNCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAANCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTNTATTCATNCCAACGAGTGAATACACGGAGCAATGTNGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCTCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGT
+
:5!-+A-F)BF:3%BF$B&=EG9?:AG+'"$&C)(.@>?(??;9=!1F.:E*'F!6B2$B4>!E&AE&)D&/H@*C0%(A<E0><2B6&.,0-C2F$83=$:7((D21E17@:-DE69209.G!/0+"'FB6"=A2H!2B*D?"$%.%C062:*:#(*5&.F$4'71F043-D&91(3*7#31-9!;E'+F@;E!F$,%F7?<>D3C@!%-$$G@64/8!4>)%=GD;:B4E%'5/*+<?@--C*6$(*:#8#@A=(:0(E8C3B>D($!:!HH,CG(+BE#*4.%('-47AE"$!37HC2=<C)&($*:@/#;7;EHC1,@HDB+G12<,4?;H@19H:H&/%,%("*.>??%H"<)3*B?8EHC/A3!F;!#FH.3B@#'*8)$(;;=1-2/9C2;?#>#6CG")C9E.CG#F!'#A"B6&7B>55&'3&%#
@r7983
GAGTCTGANGANATNATTATCAANGCCGCCTGAGTGCGGTTNTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGNTATGTATAAATAAGGAGCACNCCATGCAATNTGCCATTGCAGGGTTCGGCCTGTTGCTGGCTGCNCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACCTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGACAAGATGTTTCGTGAAGCCGNCGACGCTTAT
+
(('*&(%#&(%#&'!&"#)#'&*+%#++"%(#(&&)!$&&+)'%!'!*+#'+('"%(+*#!##%&&")$&(!#"#*#&)"#!&('(%&$$')"('(*"#*'(')*)'$&#++)%'$!")%(%#"'%#'!*%)*#)%&*+**!(&)(%&+)'!)"%&'+!&(#()*+)'!'(++"'&##+(&(*%%+("%'$!*('$"($+'$+#$*+%'*#'))%##($#!&+%&!+'%"")*&!*(%!!!++(""**&$(+)"#!%(#()'*##!"%"(*&*#+&&##*!'(&#'#"%)$%'!$#'*%%+"'&)($#)"!&)%++)%*#)'!'&$*$#"+#"
@r7984
TAACCANAATTTCATTGTCGTAATCGAGATTAAAGAACCAGCCACCGCTATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCAT
+
)'#)(++)+&$!$!)+"!""%(+**$(+""()"$)$(**)%"&)(%%+()"+(*+##$++((+&"%!#$(*(("+)'(!!+#+"'+*(&&'+&*)'!')%"&"
@r7985
GATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCA
+
9/+1)'+$E=G>@25#,E?E)<C+3G%#?71+E(G5$->?&,B3,E:07*".>C*
@r7986
CATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATA
+
#<>-/>";3,F9&++3A$?-83(F(C*:41:8=>6"&$=5$A%H9)'*66+)<6,&D"5AF6=+95&+0&-/4?F"-7H<8<2%$G93<:G,$/)8&2#:GAE(:
@r7987
CCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTG
+
)H!%'D?31D2E@0$)-%767,?G1'2'942-C419&@A)4
@r7988
AGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGTCC
+
!&+$'*!$$)*$!!'$*!&+#+$(#&*"!("+)$+$)*!#(*&&#!
@r7989
GTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTAT
+
*'&*+"!)*!*')'$(&")(#&"+)#(**+!*!(#($!$!'*
@r7990
AACAGACGTTTACTGTTCAAAAGAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTGGTTTCTGGAATTGGGC
+
><#*!/038A@%*;FB:H*,>,#5>$973E@1$)=8-$+9-44+C*F@$B):28$6%2EB&+;*6!,?2?@-&$7C+?4<85H5E%2
@r7991
NGTTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAG
+
*#'HD")G6-<BCB;1;'2D?0><=;*3;B+)6<:E&9A+);2)4G6&+*!8=5
@r7992
TCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCC
+
*.+7#39DA#"81@(65$3?329:**5EH@?@8#08#E+>83@0C@0091$09:"%G&+*9F)D=5E';(F4+5>(#H?;+D42$%#(")B''3%;$59%);D(;!D&DC;:F;=18H&**9)#(2#G=/:$?1:8+9C$;%$
@r7993
NNCCGNNNNANTTNTAGNNNTGCCGTNNCGGGNACNANNNCGNGNAANNNNNAANANNCNGNNNNANCNNNGANNNCNGCATANNNACNCNNTNANAGCACTTNTANATGGNCTNNNCNCNCGGGGCNTCNACCNGNTGCCATGNNNNNTNNNNTNNGNAGNNCANAGCGACAATNGNAGGCANANCACCTNGNANTGNACNGGNNNNNNTCTTGNCAGGAACTNNNGNAGACNGCGCNNNNNNNGGGNNTCCNCANCCAGTNNATGCGTTAGT
+
!#"$"!"!"#"#$!$!##!"$###!"!#$!"$"!!!"!"""!"""$$$$"#"!!"$"$#!!!!!$$!"$$#$$"$$"!$!"""$#""#$$!""$#!!$#""##"#""$"#$$"$$#"##"!!""$$$!$$"$$"####$#$###"!#!#$#!!"$!###""""#$"#$"!#$$"!!$!$"$""!######""#!"#"$!$#!!"""#"#"#""$!#####!"$!!""#$#!"!##$$!$!""!$###$"!"$#!"!"###"#$$$!!$!""$$"
@r7994
ATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCNTAAATTACATGAG
+
0!H593=)205?;-3.++%C<*#?/$62;5:.6"?4'@!>G:A4);5A5)+C:6+D*;(7.89;
@r7995
CAGCCAAATGNTTATACGGTATGGGAACCAAAGGATATTCAGA
+
;=<F>!:.&</9B899.!;8<><B6G."@!;22*$"E:%%%2C
@r7996
CCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCC
+
'A23@9E/72&E9+(<9#/$/'@C8+19<EE&-9:-D4"<2,4&8B)H)$7BA7#8CB!5(<;C&H!2?=8F@>)%*.H.<>@-)0'98!-+"@*$,
@r7997
ATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATA
+
A55.1H:9B4+G23-'AEE#CF>%@$"?4&.F*"51-0":
@r7998
ATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAG
+
(BF6G.-7E<32%'"!=D,)7#*A+AHC@4<3;H02<&FH48C30"@7(3<(2F3C*H5B&4F449A"4G,%5AH6">6?0"(
@r7999
TAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCT
+
/+G$F'%"98E'B5A=7&A7GB8>E<77))1!>#D:;$3E?@&#0=:6&@G0G>4')>6C-/%F3E;=:=-;$:!.3B!1F:D<?$11(>,!:'=#)1">(EC096413B(G>0F(<:@'#,$0=>)(??(4(?GC=#1)7*813%0&!!),
@r8000
ATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCGATT
+
8H+">#A3E4G<!2';H)8&;;+-"3310.68>CF;8(3C98;1)$$/,$&)!@(!*9"9-0<4$!'H
@r8001
NGGTCCGGTAACGTGCTGAGNCCGGCCAAACNCCGCGATAAGTGGANCCAACTCGAAATCANCCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAA
+
+H'94:58B-89(*$7+2=9(>:8$>GAF/(.GD7C*58FB;&#AD,A#>#3$E;!-$$,,E-EAG8H>!;":>-+71+29%8"H..C(%07E!-D?#-H"C9+;?EB-4C@$-7E.!H,=?62<0GE*FF7B#!!7E$0??)#F'01'(C&?/*?.6!!0:--:8G)>FG0D,>"@-=.2;438:%'+$-G.D$?H,(!785>!C#@9&7402F)%D3C%>!4B41B@=892;:
@r8002
CGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAG
+
C=7A&@F:<5,G'G53AEF6;,&,7>BE+7+#0>6?;66<E.$83-(3C;#-
@r8003
TTCTCGTACTGTTTTCCCCAGGCCATTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAG
+
1(56@F&.B1H;4*(74!@?!$.=3&H'-.DE(:3"?407D+>A@)&H@!)5=;'6HG<*@;0)5'?<<4
@r8004
NTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGC
+
%'+$'#*%&%"$)%*%!(*+#%$!#%%*)+(%("(&$&'#!''
@r8005
TTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCAT
+
8C!B$/4FA(22&<@#;$H/4*#61G6+!%B01:&7)=D:7!@4;:<D&-/5=/A.>H
@r8006
GNATGTGTAGAAAATTAAACAAACCCTAAACAATGAGNTGAAATTTCATATTGTTAATATTTATTAATGTATATCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACANCCCTGACGGGGAACTTCTCTGCGGGNCTGTCCGGGA
+
53;7)/5"C@>F=:*$-@6FH-<;5E2%G3FG22=#/%0!.D76AB#.)&6*3'$5(14BA:B.2..426:D60>46:.$8.1C$-H5=;>260.@&ED<4;+*A$56E3"#3"5;?@E,E#,B?=!G!7EE<&>')B?6B)(C51F)9%@<0=B@;)
@r8007
CAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAANGTCAGGACGCTGTGGCATTGCAGNAGATTAAGGAGNG
+
(G!D#=F<B058(63E1#:DC=#%@6<(2#"3.H!@#4%E1*:";<"('B$F:>?5'H:D0:##/2*%;4#C6&7C",-@G*%0/*C9*5,G">C(F&DD141&<=,#<>"(8=.+-,?*F
@r8008
GANTTNTNNCNNTANGANCNCGANAGCNTNNTNNTNTTNNNNNANATTNNCAANCNNNGAACTGNAACTNNNNCCATCGTGTNC
+
#$""$"#"!$$""!$"#$"##$#$"$""$!##"!$$#"#!$$#"!"$##$#!##$"#$!##"!!##"!!#"!""$"!#$##$"!
@r8009
TTTTCTAACACGATGTGAATATTATCTGTGGCTAGATANTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACATAAATCTTTTCGCACTTGATCGAATA
+
9&"3@D2-A%<D%7#CE2/1'+8=,/53.>#'=8<%93//C&35/H5")3DG-4-5!H((!(E9B/84"4@!*7!(6*8A)%#G>5>-!.0&&!"6;:1",0'AF#0(BF1:%*+G,3
@r8010
ATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGNTCATGCCCACACAAGTGGTTTAAGGATGAACAGNTCTGGCTGGAGTCAGTATGGAACAGCAAC
+
**+&"&*(##"##$))#)*!#!!%&''##))*"(#)%+#$*$*$""$$(*'$#&(("!&+*#$%#*"&*"+"%+#*#++$*'&'$&'*%*%$+!**')++!!+
@r8011
CGGACTTTGTGAGAGATAGACTTTCTCCGTNGTGAAGGGATAGCTCTCACGGNAAAAGAGACGCAGAAACAGCGG
+
FE5#4:>*4G80-,:;%%C2C-=,";&9+8/E71D/1<=-.;G222GF,7"EDDA2*3*D0@8&C*%)H$>=G!>
@r8012
GGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGC
+
<01&#>$=>-:4A)8B*=H@%6.8(,<2F*3=1&/<H"6!;=66/<63C41"0B%5"E?8G"@3H,-AE(#18.4E8
@r8013
TGGTGNATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAA
+
'3&>//B:5)?>,@*2:C9+G2/6&B7%H$4)!.!A.E19&+4'."F9.5,;.E"#?-/E,8:3072
@r8014
GGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACT
+
/C2/?0./F#!DC+8<*$024/H"'BC+&-,/!8+D%G--1E=@'AC;'C9#E#(9F=$?=B-A&=,5C92@?-+<$4(=%$!;!E
@r8015
TGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTANGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAAC
+
@)09/9=>G@DA.C10()&%6C'8.;89>)4:EC>?$3.FB8&)#1+.2?B0C7$G%8B94A496@@,/?'4:(-$%"F"/3?3)6+&:;:4?/(-.*BG&14
@r8016
GACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTT
+
&-1C@)F+37049=1G.3-!.6E4!9,,@5>!=>5A)#1"<(:$@&E(!70C;2E89&!D+FE4F+G2!.9<-AB1,%-1:H?,$D+
@r8017
CCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATT
+
D(FAG3%,?E:&-2&=-$?!A*47.66*='1&0%0$4,HG=(+>C%'*&+CG<:398D;<:&:258*!'3>?@%"B;<.,8!A*9$2A2')G6:7G$4=!>/9<10DC/#;?6GA88E>"<HC,'8/B+7#*;%@1:B>F:>
@r8018
GCGGTGATAAATTATCTCTGGCGGTCTTGACATAAATACCACTG
+
'EAE23-03G17<G=7%/1G5E18%EA>,-D1$!5;H&)C:*4!
@r8019
NCCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACG
+
&E+>D2'(E92?%+)=<<,-D""&E@716H-3+?=E@G?32(,5&':.>)55+$B;A=#8@<E,5C45@7@3,9/B1!
@r8020
GCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCT
+
B(:+>=0@>1>ED0A&1:&>$)5(<8/<.4B#-;76<E.8;.&:F@+;B@AD?!/A$;(!>)72@<<.#08.H":-6,7)>@8$DA<4<!1"6>3;-E@*
@r8021
NCCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGAC
+
80<'EH@,.H&16C8<,459-5;:8&G1"0EA=6&+'HGF2EG1&98E-?9B4@H,#C!=G%<4&0?F$(FA;8C-E6:-+-+7)%&++BG!#A1?;7F2?D@35810.?83/1.4>BD#(>%H+(E)6='%>/D<60%+G30:+7!,8D)&DB=8?4H
@r8022
GGGGAACNGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGG
+
A#(;1570#+/7*&400>--0.DG#BADFHH+.",AHHC-"G,.%
@r8023
CCATTATATCTGCCTCGAAGGTACNCCNTTGCAAACGCAAGGNTTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGC
+
1013")$B,'.(%04$H8?@.0D%$H75$068:'-1/&5A3.5F;H1'#490!<D:717#1$&!6+,0*HD-1G&''/((6D!
@r8024
CGGAACTTACAACNGCTCAGGCATTNGNTGCATTTATCCTTCGTGAAATCAGACGTTGGCTGGTCATGTTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGNAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGNATCGGCGTAACTGTTTCCGTTGACGA
+
5%46#;*+)=-&7*1F$<.5)G'/H6%8!&F+)0#!43E=EA)D8$'<H;0G1G#4=6H*!/'4:3F46!%;C807AA,E'$-*-C>3)=1,+!!:A?*!A%E'A#=BF7*@BDAB9<+;*D?:;A@EF7*C.95>$B&:+9!(@H:E(F*D"H+"9$D-.B=G4A/(1#F1%+%926,"7)B:DD93-AB=>*%F&85F,*A.1G$'+#4?=7/.&D8AC>%8'04>4H.8A*C%'?23(?E*$A6?';>)%7;8D4'?":7(!G36'GH;/D?0>B'7!+/<2CE@G*+>
@r8025
ATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAAT
+
8/3)C@79E">5D=?@9?@=.D4H2,>5+%CB<&0G31B@.6:"*,>@-,C=%.;E?.82?418BCF76>E7(4D'F!.',5
@r8026
AACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGCAGCGTCACGGCTG
+
?<A+>=6.!/&C197+<*<'5+=F6D03F'GH$G(75)"D+E>A+C%8!E
@r8027
ATTCGGGCGGCTTCAAGCGCNAGACGGGCCTTTTCACGATCATCCCNGTAAC
+
"+2!D>:)(2+E?;/7CF92;0)H<'48'386)E0%3'+'E*F.&":."<H(
@r8028
CAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATT
+
/,#8-0?0%&<*1@36/GG'$8-<+<=G%6)F*;26$>%;/+22A/E)4+0@BB)47.AEBC-4;F>A!9<306&>2+;#-';7,80;C<.$08%"B#075!&D87?F3.+F$'96FD.?$!<#',A<:7'688++6E0;+F@(:7A0(;='?$3C(9)&@*D=&2EDD<=B:,F>0G*G#F0&5(F=,A'6?.(A
@r8029
CCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGG
+
2,+-444=.:!A$A39$#"*>/4,*-&H&B,).+$6H%7+H!(*0((8;F-#/.:$B+$-39A9FC@D6(%41;:+>78FCD$()8(+33*-C9<B;=D
@r8030
CNCCGCTATCANCNCNTCCNGTCANNTNGNCNGCANCNTNTGTNNGNNNNGNNCANNGCGNNGNGCNCNGNANNCGTNANTNNTCNCG
+
"$!!!$!"#$"!$""#$!##"#!"!"$$$$!#!$$"$#$!"$!!$$$!!!!"$#$$!$$#!##"#$"$#"$#""###"!!$"#"""##
@r8031
ACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGC
+
->%.-C"++=,)$>A/.G-('1+ABGB*(70<G9A,54+DA,F7F;,H?5?+1DFAH3*C::5GG;70":>E;=3-*+.;,E>C-G>#A/;?(6B%+G<@1%'G?#"38);;(-D1>14,.=36*C'$&/'755:%%/.":-C@8";6G*>3368BG;3BH8"<G#52$:+#4!F3F.1
@r8032
CTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACA
+
-G@1D=F*05&<&2)2=(:;7"?2#1-#=7;"G=2FD:/)4)/#EGG-B1#DH=3.5A7(*4'2E!(AG4!?9;9$.="2F*2%'G0B@$=*#-&63+$&7F+''
@r8033
GGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAG
+
497)3&3""$H@A#:%H'4E;$8+?5.!C3&:$**;"CHG+A2H2(;+'G8'<79G%)@
@r8034
TTCTCGCTGNAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGG
+
H/#7DF#/;;;)G%<$+&)A8'3)%,&-9,6&C0<40($;>(=E$?6?,@&:D8;C;E*<5/#,>?9;2FE"F!<HB0C3>:3$.&;0D+2%#@5(26;&5:9C43>?G?!"/7FF)H3
@r8035
ANAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGTTTAAGTATGTCGATAAGGCGTTTCCATCCGTC
+
($63,)+=/EH/D5=5!!F87"G!.=+F*=GG>.*1!H3<CB;231(!*<#C/9<*CF.F<C=()GFD/%C(#'%
@r8036
CTGAGAAGCNGATAAGCGATAAGTTTGCTCAACATCTTGACTCGGGCATAAGTCGGANACCATNGCATCACAGTATCGTGATGACAGAGGCAGGGA
+
'D,4:HF6@8A'F&1A&<,,6C>)E'GFB6@2>%8D&!<A'.3,DD)"G5&25H48@*(/1%75':"=BB61&;"&9'4B*=B2?(4?&$C%#>;&
@r8037
NGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGAAGTGG
+
)G'E7'0@8F0,+!CDC1:7>F+5F<6<@9=EC5%!B&(+0!>D.
@r8038
NAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCNCTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGC
+
(4:E2!%A2!C&2HE;1E(B$231?H51"5B($-5/4#<1&6(-;'3:H%7608CA$(FFEA%@"%+&29@<4!91()1>.F-E#*H%&<968*G5@-G,+1A+>*!/%0>#<1#:>6EG9E,",-F*82,.61G>5G!F&4@?E&:-3;"2B10,.)4!@1+1)(+8@6(ABD2*>;70*G81H>@;16-#B8FF9@EH1D&H=F41.!<!F1;HF$@""+)')8A?!$=G7G@,=#0.H1E0)H2-731(=*;@;'0!/.B&?D6=.)0>:H-*@:.<6DD.>:?(+=.$A/>'?*83,!FG%7F5>@&%6H92H""3G?E4,F*:'$'5:,0$3;-4"<CF
@r8039
CTGCCTCTTTCTCNTCACGGGCGAGCTGCTGGTAGTNACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAA
+
?*@?2$'=6D"!#H9#;>(0:=@?HB'7';-C564C(B?D5!HGC'$6E+0H-=C@@*92+0(/?"!4>%@-0E>!2+63
@r8040
TCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACNCTGCAGCATTCGTTTCTGACGTTT
+
F/3#;*@43-=!4,'3C/-4#B5E<E:011&%=4:A+#0;8"07;#H;$<#//:E/529C(*8&/?B9CA4C23E1)<-4+0:+=:8>D<6D>?D1=*9+=B$5"/%G=19114$4H82D31&#7@@6B9#C7H>?<<&1)
@r8041
AGACTTTNTAAATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGAGCGTACTAGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGNGATACGGCNGATACTGTCGCCCCTGCCAGGTGAC
+
$))%#"$#!"%+$()'!)))(*$+"&(%(""!#&*)%*"&%)&")+$)'#)+#&$*$)%$'$!+##(()+*"""&"$'%##%)('!"'&()!#"$!%($%+)*)$*&*+'%"+)##(($#')))#!+##%(+%+!**'*$'$+!$)#'"
@r8042
TAGCTGATTGNAGTCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGNGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCNCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTGGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGNATATCCCAGAACTTCACAACNTCCCTGACAAACCGATA
+
*%$)!)()))$((#$$+&+!)'#)&&'!+!(&#%)"''"#))'%#)+!$+('%#+(+!')%&$$')')(&+%"!$'")'"*+)+)'&("&&!")%+*)($$"%"*)$+*'%(*&$"!!!*"'*%!"'$"*+"&&+)%'%))%#'!#(++"##)(!$$!('%("&+#"%''%$&'&))**!"!%"+!$!*+%(%'(#""*"+++'())(')$%$("'+%!#!##(')%("!#*"+'&(%%#(!)"!!"$+"!%&")'$%(**"(+((*(%"%#&'&%(*!%$)$')"+%)'&#"&)$(+(((%##!#&)'*"$+!$"(("(&)(#)+)+(*"#
@r8043
CGGAAAGCTGACCGCTAACAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGAAGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGNGGAAANAA
+
998*0AH8649@)".%3+&80?2:'125)8+C3=>0%8=-%?97%!3%'/)?,7#0&A:0>+,%8'BB!E"*?;=;""9/?.(&5&(-:6+?%&0G:F",F/#4@6FDB40)B2!8?0/&36
@r8044
ATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGAT
+
*,@%E)1-%!0(@:=#8A$=9.(7?$/@3F:,G?*;F(5?%:E)F6(@4G<"EA%A!D'0A'/$/%)795,
@r8045
GAGGTGCAATTGCCAGTATTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGANACCCGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCT
+
*')"%("'++)!'%&$()##$($"%"(&)#*+$(*%(##+&#)"&"!(")(*'%&!#'#%*#)#%&$#&!""'+*%!*%!+$&""(!*(!%&&(%#'(&'+!$"!'$'%+!&'%"%(##'(!'&'&*!&))"!)+%%')#'))#+!*))++'%#+)+(&$*%%##+!'(+"+$#!'%#)"&"''!)#*
@r8046
ATGCCGCCGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAACTGAGTATTGGTTTATTT
+
,-"5!;A9(<6'#7>98A!#CE92%6H:E+F6#G'1'"*45F,-AC=ADF%9F+;DD"=2C3)39?H-ACE!*03
@r8047
TGCCTTCATTAAGGGCTGCGCACAAAACGATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGA
+
=B*!4,H38-7DAE99=)D>1:9;(2?6+?(1F%%H:5+B9/<=@GGEFFA:/!@+#D*4G*#"*;,F*42H,@8BF>F<%68#(10E$7E;89HE2!2D1!#"F(H$1*%2A;:>-15?(6B/(!2%<C=D+.'+:1HB/G"7%(05G:#-%#9G(>(:/1@*>2-EBDB9=-EB80A'>$*
@r8048
ACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAA
+
4.+;.D0G+$2-1/?9?5:B&E/E1)0AC-><,7EB/5C:(<9)24%:$-<EH8?%.,G
@r8049
ANCGCCNNANAGCGGATTCGCGTAAAGGTCACCGCTCCCCTTATAAACCGACA
+
*"$)!$!'+)$$!'+(*+!)*%(+**+*&(%**%$)&+$)*!%"+$!)(&'%%
@r8050
GATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGT
+
//*2139'31@57*9AE=($#!-<!DAD.);2'3G&D@1F5@=?:H<;,D
@r8051
TGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCANCGTAACTATTACTAATGAATTCAGGACANACAGTGGCTACGGCTCAGTNTGGGTTGTGCTGTTGCTGGGCGGCGATGNCGCCTGTACGCATTTG
+
&+('+)*&&+#$($%"#($+!*""++'%!"(&*)+&')($%%*)!*"''&(!)'%##&"''!'""%'#"(!%()+)"!%)#(%$)!'"*$*)#*)(#'%$($%%#'&)%$+#!)%)$&$()&%!$''""#+$!")
@r8052
TGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACAT
+
9@>36F+".>%*F05A,%6G,#?1).G&*DG=B$/&+,$$2H+=6@>A$-=#@1;CF'3:E?*1/7B,##9'F/-C)00#6A8=(3#<?C)?);/3?8":,F4:3"&!3"#C$.*),:5);*</
@r8053
CCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCAAGCAGCGACGGAATATCACGAATA
+
/.":"79A$-/4<"CF</)FF%?A5A1'H>,*>8EG37*#<G/&D;5-.781./24..3!(.)5+$;CD5=#.G?<1@4.*>C#EAH4;6E9";
@r8054
GACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCC
+
;F."-8)7AB>+28:?+)<8EC)./$)#4,=5DD@,&:E8<D6*(&"?'4
@r8055
GAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTNAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGAT
+
;6,!'.F81=)&4?.,$0.76:$HF1$5/"E*49#C>E%90@#<C0A(#A1)*B=-"EGG&=,<&4*D,+',DC'3;H"593A<=&89/'GD(
@r8056
GNGAATGCAGGATATTCCCACNTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAG
+
9:H5&"8=:3)/%C')(0A>'G=DE:H&'*>;A*?%,48F#07.C?'@B*9'H#*E$+")='+$#6$+4",78:;22*39&!88;,"7!;3-?E=C2;#4F;&!!CH<F(=<?&"-')4'$5#%-C17>7-
@r8057
NGGNTGAGCTCTGTCATTTCGGCTGCCACAGCGGCANAGACACGAAACGCCGTTCCCGGCAGCACAAATNCCACAGTTACCGNGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGANATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATNCAAAGAGATTCTTGGGGGAGAAACCATAATTG
+
###"$$&+$!%$*&+!'$'"+"""(!&"+*(!#'+'&&#')*+&"!$'*(#+#$#!()*)#*!&%)'"!)+*'("%+#*&#)+&!"%*$$!!%'!!#")&*!#$*)*(!+**'"&'+&)'+*+&%!*#)'("#($+*#$('$%&*%)&('*$$("!#('($#(*&&''$)*"&%''+)+*)(##*%+)$&"+##$&&%")&+%()+((&*'&(%"$)!+'!*!&+*"""(&'+'!"+&''"()&*$('+$)&)"*(!"'%$#)##%(++!'
@r8058
TNGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTC
+
$!*8":676%-809<31?AF3%882D82D6<=&7B+$:)&22%%;H+?1A:!6*@*.%)C&C"#/D)6)C<#D9,22
@r8059
GCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGAAGATGGTTGGAATGACTGTTCCTTT
+
7D:<A;<E''7+4$H?#(A41-B?7%@*#>'6;;#AA3<!0%+D?!:(*;C*6>#F7'5%AD6B?>F!98!
@r8060
ACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAAAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGAAGG
+
:33@/%7;/!>F:!"?=7?!.C(.%EC"E(...%12>7BB924C".+H-*#;+AHD$9(A&!;F0-)3E@F=#5F;?!-B4+7A0=E;*+&2D?((9?35A>/(9$.9>
@r8061
NAGACCTTTTCCATGAATTGGTAACACCATCGATTNTGCTGGNNCTGCTGGATGAACGGGAA
+
)59+$,=<@3A8B.&FF/-/70962-D+,+E$,,)"9B).**7<,"HH20E.CAF.@;!3%8
@r8062
AGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCNCCGAC
+
/"41/=?)$;+C1?:?C5>,"CB9&)>C=#HHEC:(F#6+G2)*>EG0$*B42/H-2!AD(
@r8063
TCCGTACCATTCAGAACNGGCAGGAACAGGGAATGCCCGTTCAGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGA
+
G2(%);$/B>==')1EA:!!>7G<$5FAFA=1H6&0.;;+7'2"<'74G'2;!>1;70$AG!#0;)@<D%7)2:?!E?&?1;(!0G'0)'B;??%=C9<>:=8>&(1:C75")28=A@44>
@r8064
GAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGNAGNATTTCATACGTTAGCCGCATCCCTTTCA
+
+"(&)%'#"#$!**(+!!&#"$'+(&!(*&&$+(&*#&(*%+#*'#*'))!!)&)$%+!%#%!*#(#$
@r8065
AGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCNAATGTCTCAATATACGGACGGATAATATTTATTG
+
)::3<BH)2!5C+D-*'?9F?D(AA!)8*<?F33HC@003%0"G17=;E$=;&1@:"C"/0#78(DF%6*0>ABB"
@r8066
TGNCGTGTNCTNACNNGGCTNNATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGNCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATAGAGATCTGCCACATTACGCTCCTGTCCGGCNAAGTTAACTCTGCCGAA
+
"($$%!%$$$&)*(*$($%"!(+#$#'(!&'%(+&")%!$($))*#")&)"$)$#!!#()(+#)"*%!&!!"($)!$!!*('#!'%&(&$&"*$!%($"()#("'#&$'(!*&!!#$)'&&!*)"+"+!!)#")%*#%"'+')#")'!%$)+*$*+'')!($!#!*")(#'+"(''*&&*)!$&(&%$"*!!+'++)&*&*%'"++($$!"##$$#!%$"'+##(*)$%*$!((&&$%*#+(&(#+)&%#!%!"#+
@r8067
TTGTGCAAGTTGCCAGGAGTATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTNACTCTCAGGCACTGCGTGAAGCGGCAGAGCNGGCAATGCATGACGACTGGGGATTTGATGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCG
+
5$B36,'&!*C&F)!(.?G@E@8H!#+/00A1+85=E&2(.9?2>(%4$&E+/D%9*=7#&8F=:>E)=";HB&10/E@*!:4$32&8E@B.!!F>&>6:310'17(06DH?26?;?FD&#-95A.-&-@:2:32>*DF-')FF)@G/:5:+<D9@B@/65=$?;54=A$<+;*>";G>:ED;;>)*;;#4/*69%F;#%(;80E$)GE)(99&C-(
@r8068
CGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATAC
+
GDA<H-!6G@,;%''D0.A&.)%?!(D!)!1G712(G94,.+3/(0":7%A;3-:1A47=%5?;7.A5D%%E$=
@r8069
NGCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTG
+
!!+'+%#("#(!#'$+!!$#&#&*&++)'"#*&"*$&$"$*(
@r8070
ACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAA
+
7AF,#9%:$>=H3F.*96.#)0*80%G!B*:19G',.!<-H
@r8071
TTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGATAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCGGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGNATGGAGTGCCATATTTCTTTACCATATCGATAAAT
+
"F"+A60+GH,5?*)%C4:9-9G"B.C47/)@C>1<@=;*>%-'EB4%C08/@3?)9=4E#8%>G$40G$/'9"H/1,/+F$@D#H-?:(%54)3H37@(-*&:@E2A9$<E$3),-<;;G@!0->;@0B.-+B?/;*@@?=$H;:-(C(-.+'E)3$4E$,15;G)%B*@:#C==*H+<9@G"8+%2.,%:(((7<%0A,=.8+838!@<H*:701>H1D><5%"#.4-7<C%,6<=/85)+>H3"7.D<,%-:,22'4'"7-D8""H#0/<*A**#.)%9&G>*-66!72)":"(E+1.A:F)D
@r8072
CACNGTGATGACCGGGGAGGATACGTTTCACTANGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGNCCGGCAGTACAGTGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCT
+
/&E-/);#(2D=F*//<&+27('/AG)%#G2:":966?GG/<.,0!#H*$?22-CD*E.-7+:1?9F=)6>.;/*A.3"*,::=.>0@;'=(<!$:%;*4E//2>H69%?CB4C":&B2!+4BBC.$*.0(;#)#*=H7/0&$!$B5?HG(D?94:2F3:>)%GDH+A.);B,H?@&*:G"=);HG$..BC5'-H,*@8A#>&>@'4+,;7-8B1'>G%-)=<5B&?<D'4<>'4!
@r8073
GACCCTGNGTCGCCNNCCGGATGAAGATCCGCAGAATGTGGCGGACCCGGCTTACCG
+
5.H8H2==1FEAEFGH;F?:+&/4$"H52!(#/5B4@B#$2%)A4$'?$+$8)7%,F
@r8074
TATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGGCAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTA
+
.C@-EB?6G)--8DA6$&#+!EA)5F%G:"'447H70B.!C;"C&HD,E0;&D0C:?%107;6)()F.@6*?&0=<&'"-&0G4/',08;(C(G;&D-''+//&!639('&&>E?("=>.,2'$31*-B.4DH8>@#'./5C*@G;8<+:7?7G&-)C=*H1;/FA"86&%3;5/4C#E&/54@!0F6*3523:=",'H>6@<"D09**072#;).@)B!/A?<BCH;0"GCG-3E*7,BF'C@-C=.+$9%.D11H!#;(:/%1@66G%2=?AF$'E1'D6126'AA?$)H&C419CA.'/,2
@r8075
TTCACGCATCAGGCGGATNTCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGANGGTGCGATAGTCTTCACCATGTCA
+
BB((1@E=%A925=0*-"BD0.$2H/)$6,96H"='=($=03?9)!@8@.227;)D<<'F2:C+!%&$"61$?"2/?41FC'
@r8076
AANACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCG
+
&)#HBB(,E&6*)(>//5<?10EG:6E'15@7H&;?-!54'-E+:4.?9,(0(4D=@+&/<=G(05$1HE!;F.E"AE<GH'@E$2*$G9,55A@)7)E/0GHB(@?;>=B9(2#198F0*54BC2<5"<A6"1',!3.;%"1."&44>/>A@<5@2B-0@<AD(D!&",/7?0'$3:.G0@/<&G3G&"2D+8"B.8#0E$-!+*;E"'?D##C.'-3#
@r8077
GGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCNATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACGAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTANGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATNAGCG
+
7(&+$(3'/%$7<'0/$A:0?#2:#E#=25?.6GD<&B7725/*H(!;8:&9!A>!.=/BF?53)H:-%?7/B+*<A2H'G!;/,GE?C8%0"3-06BB+#>9;14!6)+E"GA&1!<*F/#F#.630-F%!<=*)H2@%77.D<4G@FC7'B.CCE?EB2$F<F07'6822H.'A-B4/(4B1@%0E,"5FC%D,5H+24!##$#%"'@H/415=E378?./;!>B6G=64&$:7H.D&B&(GF)(4
@r8078
TTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGAGGCTCCGGCCTGAACAGTGNGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTC
+
8':B:#?/7*2&)&1CH(D*7/=3+:%4?&3!::9;F@1=GDC1.+$"'.2%6)?-61?%F734/:(EA)'555B3B0?6$)D,49C)B',>%,%)>;#!?BD8D8A9&E0$8)1271-)"91C:@A
@r8079
GCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACNAGGATGAAGCCGAGCGCATGGTCGAAAAT
+
D:.E?.:"$?91<F89,1A)*D2(;B(D?:-+,.BE"E,<02D$38=2B@C*:<;CB4$<$5-)H8
@r8080
TTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGNGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGNAGCCTGGATTTNTTCTATCNGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGNAAGACATGAAGATGCCAGAAAAACATGACCTGT
+
?A=E"<,1.+!70-G1?:15&8D&25>-CAH+(E3*=6,B49'DH',3?->4/A)"BE.7,,+#'7?B!=%*/69DCB6>09:.7B'?G8%(-(H<7H9/7.$)"A5D!07BE#3!76'!$C-D@??(,'16<@';);A:-@07#26H1).8:B4544(>*?%>+43D!6.+<0H#488$/.C*+<=0@>C0&)F$AG;=.+-(+80A.=47(:;7'#8D;B;:#E@A$9EF2/B*18)
@r8081
ACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCNTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCG
+
G91)H.DA/D0G$59%",;%H:2)664%:=G5+D=(BH3EB,7?<7+G>*,D(!#/3>9>D'@?#'B5<8!'=9!?E6$58#5!$+D-9(965890&?#D)=?.,)E!CB)*>(>:?+C.?C?".!F<F3:%.F8<@EEA4#DE)EE"-781&G3%:-F@$=
@r8082
GTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTNGGCTTAATGACTATATTCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCANATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATANCATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAA
+
40"99->D-3:'?/+9F;A!(.A*D$<=F>7FGGCB1?FG&:?4$:%$&1+.'@A2:+H3FFD@&?6=HDE86'-/0/&$?<%<$6E5:?5$D(G<<A?4150;A23D+<&%"/,"2-1,EGHH>4E(/!C28G#*.-E7B,<4#C'A36@'%)3D$4*,:$%#8C(H36*6>'2<+:=EC8EFA<@H.H6B3B2@(G)6")+2&**'%A'!*%?8"5*-/C3)<(6)9&DA-49@22.>B-2<5H<9!,90@296911,:-3/40G;G?HC7@&,,*E&,!5(@)FF)'/986(9:9>1-;2$&-2),6C>#1G05,536B-0B$#'/>
@r8083
TAAATAGTTTGAATGATTAGCNGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTC
+
+&.'C1=4&H@829&1'3BD'B)%#4!C%-7F6H/6,)52@&:-<11=55%,HD50<)1E
@r8084
TNCTGCTCAAAGTCCATGCCATCAAACTGCTGNTTTTCAT
+
%($+&!&)+$"(*"("*"%")'&%%'"%)(*$#!*&*+)&
@r8085
TGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGT
+
EAC'*#.4=(.CB%DB+AH)FA0B>>%H)7C7>EA+.5H0E55!(3H"$455%0%67$4
@r8086
NGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAA
+
"(/E#FHD:)8%E)A/CHAF#:)@B+H2</#@EH;-C9@'2%9))#E>A#'DC#$#<0(/<2G.%9($E.<>634.4F"7%":)154>GC+>CHG>=:A</#B'+1&8*5(=@'!*E06*F2G=0$4+<"7:F,>-@*B&1.28>73<>A&+)25@713.78(>9G;1?+D,GCH,C4"4)EGG=49AC*5EFA8+9C*
@r8087
CGAGGCACTCGCGACGCTGGCATTATCCGGAGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGNCGGTGTCCGGCACGCTGGTCAGNCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGTGTGACATAAAACCGGTANGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAG
+
2F3=6)8D=*CC;>.;!'>$&@700H5?7!G#30?B?7*<54.C=;??:6(-1/C93<%86%71?3352G6="#C*<61.40$A#<83!6B('7)2=)6.@7<&G/2<8#D309445G16)=@&!(C16?%$E0)E27%F=4+%;=!&/=!">!'>68;.(C?%C$$C=D/1B:A(B9$2#2=;'71$/9.D1*83!$H%.)101(,"*$E"H#6&DG@$HE.77$/7)D*,!7@2!2AE+EG-C1'>,9"9?8A1=,4D,6$C%<:%!)+8*:.74>8(/36=:%3#48BF.296>@3!467+4%68>%7B;B8H"%*%$?9-/5E82$0-&&#-9;*>HF4&AFFB14@H,<!-A(H);;H19A%;DA*5:03,G,E&F4
@r8088
ATAGCNGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGNCTTCATT
+
**-7,0?--+,1.8B9.$3$&7#"E!E3<H6@A/9A=%#"$)+.53:18$:1EH?92B34G=&B-?5"&"7?2*G.6DF=2.C1H62$#>G003=G*1<B':@0'/$616D!&7@!@E"H27.0F;<6/+=--5-CAC'5>/!2@69;9C#>-.E72B?
@r8089
CCCCTTTCGTTTTCATCCAGTCTTTGACAATNTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAANGGTCACACTGTCAGGTGGCTCAATCTCTTGACCGGATGACGAAAACCAGAGAATGCCATTNCGGGTCCAGATCCCGGTCTTTTCNCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGNAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTNGCTGC
+
>>,+D,A+879;<-$B%/4=9%8/:?$1:4';+G2*'.=*8B1!3E9?B.<F>812AC%&8@5D&<F)**!-://$9FA2;@('F1F>:4D$$1H?,F$;)40GCC9=E470(!-3..,AF4%8("=>A;,&'F"*!7.''/##-E'C6='&.-F-HD:$%%2:D&%C-"B<D%53!H7C<&:5')<27H1D7"H=(=034A::6@4579?'(3B2<?C2?1G$)6E3*E9H1H:CG3;%,F;+@)#,,/':,+G3!@<+/)"FC9(?02+B=(<*-+B2DH$1D!G7=4!1#G9(;**5A$%;/?/2BC4#*'4#@0>>@)30-&24/F5G>4$$;5016!3%6>=,*2A#:(G#((C+!97:/>
@r8090
CATGTCCAGAGCTNATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTC
+
!G<=A52F)47&HG.E:8?3"&2&A2?6=..F@)G-.?D%/A0?2EG:E*%'FD%!%!7A0<=?9>0#C'9"#
@r8091
CCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGC
+
&+")!)%$""%+(*)+$)(%%&#&$$&'+%#)(*'&%*'%)'++(#(!+**$!(!'''"((%*+"($+#$+)*"'*))!##)%"#&
@r8092
AGCTTCACCGGTCNTGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCNTCGTCACGCAT
+
$*+&*&+*("+%%$'***$'!#!++")*$''%!%%)#(&%!#'$"%')+(&)&&"&*((('++$)+("#'%##"(%&(%)'')+#&#$%)&*"
@r8093
NTNTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATANTGGAAGTTCTATGACTCAATT
+
*(#(+"&"&%+'+&!'&'&&&"&)""")+!$"&#%#$"%+'%&+'!%+)#(*%&%"*$&+!#''!%!(+*#+!&#&"('#!)%")+%)'$!#)
@r8094
CGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCAC
+
$)3&2EEB$0E,6;:#3866,!*:<?G=ADA:-('!.00<6D06@29..;&&!AF*BAGC1)4"F3EE7!+%8!AG
@r8095
TTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCC
+
3"%(.:8264.<"4?':.*=!F#;4422H)+58!&?8E5D3:G)/B?%2&6?A"6(#3?40$"HG?.:3A%-7+:/(-*>43@3&#-+)!=<HAH3$+GE9<A4).(F@'?*!#EF*22*D8+!53*;H;*23B$)@>,)#.E2?9!"'@B
@r8096
ACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACNCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATAC
+
*?H'*=%G8+4%F;"+47;'H-C="#C"7/0':1>C&>08H;':;%>>0C=&:.59)F05GH#8.)0!<26>8G6B#FH#)D..D?0;%::$-?,
@r8097
ATTGCGGCNGCACCAGGCACCGCCGTTTTGCTGGTACGGCTGAGGTTTTCAAC
+
:+/HH89?$*2;8<71*9<84&%;.H$6*;B@(@?&7H-@(<@H*&3<B&6'(
@r8098
CCATTCAAGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTNCGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGNTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACNGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGNT
+
?1<:2(57:?3D>F8C%2C%/;490=ABE:(;!"8ED<%1.H8F4@1>D)7B,$%>(4C<&>)8@@$.=3$9&A@D-1+2FF.H'(1=A,.E0*"')<DA*&G$<+!>36</2G93.E(HHC;/63E<'4B2.>'HE1#&..7?/%H>*$'78#A:!H%?$(4#3@25)?:E0?-<(A<$B#$;)(A)7?%!:4>(:"FD4/'4H%+F>+@22)'EE,=5/>FB>1/#H/D0?8)(H-(02)(BD?E==*@0*/-)4;G+$+@9<2862/&:!<..+5&(2@/:<?$42616C10CAA#87@4D82E?%"6-(=ED,B*$?1BH.D#?
@r8099
GAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGC
+
37:>>)6F8"?04>6%*G(C!0E;A0."-<F86H&1-DH,D)C,+*C=!B583<46831*D)@!%6C'?C@D999=G=+?9"<1;D.,A911&%<:5B&+5@>"9=$#0+&'>)@-82,:*:=851C;3:C%%69%@!<7>+%",$<AA$CCD-;4G7*0F(,%0/#CHF*:#<7942>HB=,2C7
@r8100
GGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGNGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCTACCTGCAGGATGACACTGTGCTGACCGTACTCCACATCCATGCGGTAACGCCCGGCT
+
8)17/%F*+E%8%G=C092<9HHGBH2,6+8$=4F=.?-,2<5!F/;2*65E<.F:=3A$63$F?;5GH@><2&$+E7.ED@3(;9H$(D,0$@G4#%507)"$..@(<=0(&6,#G;8"1H9)/$9G81@?F<4C0"%>FB+BFF7,2)61H!C6C$F"@<*9?
@r8101
AAAGTACATGGCGAGTTNTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAG
+
-D*'05/D@(#&7:684.B?3)$D<>1@;/$DF?<("!>3H'1H12(87*21%/<2)4
@r8102
NCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCNTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTG
+
%0@3F'CC?E(F(+&B<B&5B=3=CB-3-@HD+CG4012;,21")8,A!,$?.C=+=%$:1A.(>+?')9/;<A8.=H/9
@r8103
AACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGC
+
F35")<4A8?E#4G:53)".>2A450<>+5F>*4BA85!,H4C0:E/&@911.7C6/'
@r8104
AATAGAGATGGTCTTGGGGCGACATTGTCATNATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTNCTAATCGG
+
$>8*1B#"#@'+"#D7'F"9-/>(A721':9(.#G>H@)=##2GC-C:$46A47CGB@C8%4&/970&$">.0(%H4A34-5,E65
@r8105
ACNCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACAT
+
($";485.+.E4@6A?B0CG.5)*8)%#'&6%9-#82:6>674E+(+@;)3;4F)C*'#/;2E36;9)&-;F3>E%8)2D
@r8106
CTACNGCCGGAGCCACCCTTGCAGCATGGCGGGCAGCCATTGGGGCCGGTGGTA
+
!%*+%"#&&'(!)'&*+#%(*&#)%"'+(*'%)'$+'$"'*+%+$"*!+"(%((
@r8107
NAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATG
+
"-F"=",C!!#9;/H8.6#!$7--A!-E)*@"*503F)>><69773;!0$E$EB4("G$"4558';F@%3FE5@<6?(57&:3DB;@=-G+42A3:D'9*FAH*@6,,%.&$/,0/;@-<=$++.(?EB%0=/G-5#CA*/AF#C7)#&9(#2F"8$*.8?/:07%@+#+785CE-;9>A':'A
@r8108
CCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATNCCGGCGGTCAGGTAAGC
+
&A+F6"E69A'6G=$/1%G,B8.9)(>D+7E6(,<%':=+)D%A<:<C#7('D<2<&&+@'B=<5)G3&>1!(8G@>?:&+D:E?F%)84)4&#G15CF'=&&E-=8"1C9+!**D37?<>C2B$B;7+D8!&+@>'7.&-$1=0
@r8109
CAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTAACGAAGTTCACCGCATCCAGAAAACGGGCGTCAACC
+
<>809B,<2F8<2+0D89$/>0+?F6)G+7)%HG-17=7;G=BE(-H"'=$@F6(E2@71<H0*'HGD'HE$#A"90>1C8=(HGC9:@D5*?1B"E.0&?=9:&,0.)
@r8110
TGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTGGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTG
+
C>H9<(>6H#&;'A31>/06=?/;>%#"-.D$H21+);C'*%5<-"%AHDE6?7%;/0C21'G6*(.><;D%G;'C0;<&<>76$+?:;:7%F-F#28)@,&:&B$@",A)66>)?E&.32'=E,<9$1(A!G1(#GBF@'/<<9D402&>G@'+A*4;6$'H29
@r8111
AGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAAT
+
,)?B)890>@=EDA?&HH&FC.%>G0@7%?EBB53%&@"!@*@"&H<$(#G>"!:2;.:-D8*0C#1
@r8112
TAANCGCAGTAATGTGGTGATGCNGGNTGATGGCGCGCCGTTCCGCTACAGCTCCAGCGCCCTGAAGG
+
6.H71%H;%6AH@"6$.<#3+:!@.07/G)?E);GBF;31:#D,5*C?F@.(G##7@/4=+"D)A33G
@r8113
GTGTGAGTCATCTGAAAGGGATTAACGTGTAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGA
+
743((.0+&:9G-$'1!3HCE>E?;#1;C)<.G;/'9>2!?G4<-BD>,)('66*@*.1,>H(72>>!(>G!/G)=+>+C.3!*6)3!%A.F9.3F9)C9"7>(@HD,>(,C@15!&4E89
@r8114
GCTTGTGGAGNTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTANAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGAT
+
!7=A1CC"6#;+384;?=7<;+#8$!;)&D3,3,7=,7F6-)B)?=FC@&CG@<+F>B)$0+,%876*F+(&9)D=.+1:,@1%33'2$=$.408";$7BA;$@#?;%'G?2(?@'75>20BED6&,<F/-H==H;='6@;C414;B9";(F5/88BD>;<$!(0$$0=DC0DAC:)%H&4G*2H+,*#+!A>0.F50E7B@*$5&6<G5AB<-$EF/38F=$<+49;?5<1%,5'B/1C
@r8115
CACTCACCGCGCACAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCG
+
)C<DG'>,#1A(&B%B*<-;A;3+49:H%>*D+8#+2>9.)B1>B48212?36?.HEGFG!A!
@r8116
TGNAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACC
+
2%C&G#/=-1C132B+"10#/D.8<6)7C54#D68=E..77HG6+G":,*E103*BB&B2F;A:15/"=F9B9'%+&8?5C!8$&5'7$@57-!E#
@r8117
GTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGNCGATGGCGATAGTGGGTANCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAA
+
3*.C1*C-#E,0(>=3(.>E=@B;E1!*)&D,5%;BD!0H;+'FF*?<7%,$EDF9?A%2F'0?2G&$4%/>H5B".8-CH,/C:$=5DC/0&3="4A1C;7-G2%!$9.82G10B:E.<#B55</CH(7:==9,'>)6B<0&8-H!!:A&8G2ACEE'/E51%-@0,96H?+!D3;<8.
@r8118
TTCCCAGAGTNGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATNGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTNTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCA
+
<=H'H%,0@?B0C9>>+(*<'D))=#.?6A3@A*/'8=F4&.>-7.)9-,A!>D,27AF"0&A=!A/1D=CE%)9;C?*90A'#87+'&)58-70D7B3/&G$#$BB6FC8.6)*"BD>2'DC75/E&/GE19A'"<C!(C
@r8119
TTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATGCGTAATCTTTGAGCGTATTAGCGGCCCATCGTCTTTCTAATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGT
+
,F&9*411;3F)0;-99/#@'44*"@%7@.A(&B%!.'(A$?:15AF;)'>19?$*?&4ED3:2/;%!&H*F;:3"63*-C8%-C*%6AA:$;<>;95.&)(F/+5"?E2.">98F<1BAG+GB9?<#H(=)&B.
@r8120
TCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACC
+
$G"0A)=0:260G!=45</B<8B5C4;.BFDGEC9?(!('D0+*G,
@r8121
GTTTGCCGGGTCAATAAATGCCATACGNTTGGCGGCAACCAGAGACTGGCTCAGTTTG
+
68@73C23E7+&8@/.4!50DG3$+<-;>5<D71()A37$/3?1A!&D0(:9DE"GHG
@r8122
NGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATT
+
#$4'#&6F@$;8#(D<&84!;69C=%3E$>;89#"@)@E)>&3>C@
@r8123
GCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGC
+
%(6EBG&-DH#+*+HAF@.1?2@'D;"F!48!+7::=:*G#9-2CB(B%6C;?="A4-15A<9/*?'G*<<3F#>7;E
@r8124
ACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACANATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACNCTCTT
+
5",,9%1:4HGA.$/49?B#:-D068)0.D/<$%8./D0EF153)%DBE09+3=F1*#2%D9*/+A</;09F=G'=<>=%)C;@!441G0*;#,2D@.B..=1<G+F3(*10H!F*(>>C;1-=5E*>B14<@(9&!267":.B1-EE*G.,))&8%>)<%G3(#G&8'!7H+2H4B)(G>G%6B6!/,.8
@r8125
TAACGATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGGTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTCTCTCAGAACGCTCG
+
E5"5E,7@/5FC=%=H:=0=@*C@5672<@>#72?+<A3'4"'31.65./-A-%>5F5F7/$%#>">)?<5&=FA@7'+/"D0"+1(C4<3GFA9-<B3EF@)B-"$</4G'*<8%2#H,$?>&/1.D,E;0CHB8!?6B>&GC-C0C&>=G$,%
@r8126
GCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCNAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTTTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATG
+
32'#FCG9(9;9!,*225@78=!&7(+42+&$HH0.(6!7C2+F62+E>:;C&?H#9,-,)<DG++H"2E;CG("-6'C.*.EB1%9.3E":8D289(5<A#HD60F"!F52E6;>=0G>;,75%6?;1(8B%B+"$.1B?AHEC*2:01<D-CBC$B:(&*,D
@r8127
CGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGT
+
2!!+A'1'@)312,@7H3H*C);G3@33<2#A0-%'(=924!(<;B/145&>"1*.+<B3G>*>HF.@*&'B*6$3="D0884<1$)!+
@r8128
TGCAGTCGCGGCACGATGGAACTAAATTANTAGGCATCACCGAAAAT
+
&2!99GA16+4C+=->0;&+!6C;%F<+050%:F"H(9,<17F6'BH
@r8129
GCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTT
+
@G(6'G-:,@(>2>.8/.@"86@*1"G"+>)*$0@C!63&$:0C&7*&<5.F'9B7>
@r8130
GTTCACCAGCCAGCCGCAGCACGNTCCTGCATACGACCTGTCTGCGGCTCTACCATATCTCCTATG
+
7'8("4$-D-(9#.6#-EG@$)@+HD039F:+>>63BH$864C2<#@;79*(GG>3*FA*&+E-?>
@r8131
CTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAANGTACGC
+
<!:G$<5*DE=&?G,&;?%4%@"E&F4<>A8C>*7D>#@C::(5*%#F1351)2F<:#5?'#(/5-"E-DCBCD1
@r8132
CGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGACCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCA
+
E>6):6"9/H%C.C=.*88/$#,>G$0"=*H";B0G2.*F>E=BG)5>-"18=/;4!FHH3E?!><8'&F!A)>0"-D:(+$1/5BD(-%>;DG!>2FF*%9>6;$CGG8
@r8133
NAGTANNGNNNANGCTNNGGANNGCNGTCANTGNGCGGNNAGCCNTGTCNNTNAGNNNANGNCNCTGTATNTNNTGTN
+
$$"$"$$"!!$$"#!#""##"!!!#!$!!#!!#$$$#"!!!""#!$!"$##$#!$$$#!#$!$""""$"$"!!!!"""
@r8134
GATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATNAATTATCAGGAGT
+
<GG17BA?$:HG(;-?#H#A*2@-=8;%"8,E$#>?1)5",/EA#89B):!D#74$57$
@r8135
GACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGG
+
940A6$3)*HAG"28H*>&DE5&0!H:??"E!E-28-+(9-?H;<3E+<4%B7E*>;A6!=
@r8136
TCNGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAANAAGGATTATGAAGNGACGCTGAAAANGCCGAAACAGTCCAGCGTGNAGGTGTCNGCGGGCGAGTCGTCANGAA
+
%#+'"#!+($(*$&&*$#%#+'(*$!(%"($+&'$+'*(+&'#"+*$)#&+'"*$%!(#"!#'+'##!+"*!"$++$*('&*#+!%%#&*&"!#($"#$#&!$#%(*'%)*#!
@r8137
CACAGACCAGCTGCAGAACAAAACGCTCTGGTCNTCATACACTGAAATCATCGATGTGAAACA
+
9B,C.(>A**HG=3D#@';,G'!D'CD*$!*6B3!>@$B4,8&;6(<53G<2276"8G!D6)@
@r8138
CCCTTCTGCGCCGACGCTGAAATCCACNGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCNTNCATCTTCGTAACNTTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTTTCGCCGTCTCCNAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACNGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACNGTCGGTCCTGCNCGAACGTCAGCGTCTGCCCGTTCCATACCGGCATAC
+
51E*/E)H:"7;;"6$4@&.*3:"G6E)>:3=7;?:A3?).+:E;D#;.$+:F;BE0!7<A$$/'?75!0@>39:2,4B84=(%:>EB:/!B1G.FAF77)"3;@(2ABBH1$:&%5/.H$<6B?0>$@#9?2,C=%G9=A+#H#1F"29F5F"E,!>F#617&"0)E!H0)ACD47D>E?('$C14E$2EA*&:E26#'#;:+<:2"4<'C1=173E,58=BF82)@%9"H!.7=&'1D;BG649,H?5+6?%67/%9+<6>*8#3+.A)2$H'-->+C@,C)3@@$4'8,%E"7CD('%8*3@@<>=9F1B33-&=)>@87%(1?+A$<B*5@1>!65G5?5&2"*E>B!*,4#H/6;GF)H$=+G
@r8139
NCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAN
+
$&+&)&#%*$!%("(%"&$$*#$)+"+$!'#+&##&&"$+&"+$'*)"$*)'+"+)!'%!""''+&+'&%+&$&#*("'*'"(&'%"&(!$+$!+"%"&"$%
@r8140
GAACATGGCTGACTCTCCGGATTAACTGGCNGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCT
+
1"<(C!!GB>G-3:5(6@)2EC40B?A*;.(=F;@+#H80?%0.,=G-3"/<(?.78'=?/>G9D:A7#?5B@,3=A@6<')'4A9C9+-%H6)!<??/5
@r8141
ACCAGGTGGGTTGNGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATC
+
."0D#*B;4+:0A>%7857#:%1?@B@!:5#!FH.@D?*#7>46H6GC"FE+(E#;4%C'(H0D&$(5
@r8142
TTCAGATGACTCACACCGGTAACCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAA
+
5$..")CA%C+.,4-@'F,D0A!:*4!!(:1>C/=H,.*>26,=?>5(B<1!43C&B>%@=')$
@r8143
TATACTGTCATCAGCATNACNTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTNATTCCCGTCCGGGNCAAAGCGGACACATCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATC
+
*058HD',;$60-?F(7;(*B!5=1<8#6B9F63@GDHG"*E;E%%:".A2(G+;=*@!:#:$9>#,1:=EE7G>?0+5FB4@50120H=<D5(G$388D(@A*B6*!)/2!6<'-4%2>"C:&+=3F=&$=6F<H%>,/<)7*":08.&#+?0E&!.6(.1-15D:8,.*?%.=0HF78H2G8?1EB88D<=F
@r8144
CCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAA
+
@ED@0FD5&<.;1+;D)*!;/%,$!287+-='6(,>*C</2
@r8145
NNCCGGNAGATAGCNACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGGATGCATGCTGGGTGTGGGGAAGTCGT
+
&*)(%!"+!!!*(*+!''!*')!#(%#+(*+%)+!#**)'#+(&%!*)*$%'$$)%#"*+'&""#++$($)&*))#)*)&!($'**#'"*#%%&'$&$'##%!(!"$+"#'&$'*$*+$*%)$%(
@r8146
GCGTAAAAATTGCCANCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACT
+
5&E)/D:<#>&G0/6..@!1:H#CE<7G=2E#01.,%BG33C1$(9-/E3C'1GE1@>;0H*<3!<&G"8"8H5F'1,!H=./BF7!@@H?8A;A8G,G105=*A34,#(F&G(3!<#'$4-G0*24*'.6&G:7(<DB0,8?2@'D0-E<,/E,*,>+/H8G0:?:>'100-GFH;+"0@>+=6"5,E:-*:ADG:(&%:E?,"=>#$4#1;-+26@9/<+E6CAG(3)G",#G,70@;-
@r8147
NGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATA
+
"53A9"'>(?$)7B@60'=E.!&FE5B,9F90-75980@5C><C+5C,8?.*1>%*,B)2>,24@$"="4G5*;7
@r8148
NTGNGANAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCG
+
"%"!!'$'+!+'*(!'%')%*("!"*#&'**)+#)$)!%$(%(!%+%)'%$'"*'($"'&'*)&($%$&(
@r8149
AGTATGTCGATAAGGCGTTTCCNTCCGTCACGTAATTTACGG
+
0%1;!59%F@;'*-4.-CAG?2-(=%;G(9!>)G-.(HEB'G
@r8150
TCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCA
+
9.!A!@>&425B32=+:$%8E26BB<3.5G9"""$:9E;90:<&*('H#:)&('&4#D-/E)577@'%F@D(>?#"6
@r8151
AAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCANGGTTGTCGGACTTGTGCAAGTTGCTAGGAGGATCTGGAACTT
+
%@F@;!$E)8-7343-/0@0(G>0-"H17E"681GA4-<$B-2=CCCG3&6$52;?&-'.94&)>+CEE0/&%-$=;.38!H*?,:C1A?>2/779G*+D<D6C95"(-46D==/<&:C!/.D6<B@=0GHC?%;
@r8152
GCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTNAGCGCGGCAACGTCCGGCGCACAGAA
+
,8:)5!>:(?*7;8#>@221%H.@1*E5>'E@F#B0(25">HC1.?:3".7/H,&@1>08C0
@r8153
GGCGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGNTCACTATACAGCCAAGGTTGCAGANAC
+
%'"7@'-4-.B586?"$=DF9%B.B$FH>A8%"$@5/F;F%+3E"<>+9(B<?&)E*;;"$GF&4AD2
@r8154
AATAAAGAACAAGCTGCTGATGATCCCTCCGTGGATCTGATTC
+
")*93F81G;$=9"E)G90/43GE2':."!C+."=-'="@,G6
@r8155
TCTATTATTTTCAGAGAAAAAATATTCATTGTTTNCTGGGTTG
+
0;&.F7.>*3:<3D27H@,5.<=.(C)C5,C4H'<D>7EA5E,
@r8156
GCAGGAGGTTNTTAGCGCGACCTCCNGCCACCCGCTTTCACGAAGGTCATG
+
%-@:'&3<606G>)C3&,C-7B.F3B1(%+12#-"%25H9/%:/B-:3&.3
@r8157
AGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAA
+
'%+$%%%$&"(+"$+!&+"+$'&##"%'#(##!&&$)')'"!&
@r8158
TGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATG
+
A!H)=:A@DG,>GG&478$D5C9&>(%D&2D)BAF:0/"=A+!<D%8!E1,@=4+'".
@r8159
TTTGGGTAGGCTGATTTGTCAAACGCCTGCCCNTGCTTCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATNCTCACCGGCCCCAAGGTATTCAAGAACTTCTGCAACGNAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTANTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAG
+
F>H@>=-;$1F#*##8/$?<>F)-465,--1>,:!F44DDH=+=%C0=;D)!3C%-B%"-+'/H+F#"#/@%;<#%-8D49#%EBB(?04/H*#(<52*F/7/B)*9('5<H("$AE!7"5.D=H85((>C6=D,2/6;'(6@#6G27$=%63?*-&+FD:@.0CE1,/G&D.&$),'))(':=?B50>;>?(4!(",@$4&/3#<F+/$7F30)=33(:8#F<,H:F*8F?;G4(C6:',&>G53$=B2>65#?9E%>F6;"/>9:+B40>">:6=?;8D>DHEGF$)/>=.1.A!5(1;H1)02"DE4$8,'3->"!H6#F/!@9/)1A/3:/#A*#,;0''-',&F4455(()
@r8160
TNNTNNANCCTNNNGNNTGTNNTANTTCNNGTNTGNNNNNNAACNNNGGNTCNTT
+
!!####"!$!$!!!####"$!"$$!$"#!"$#!$#!$#""!"$#"!#"!"#"#$"
@r8161
GAGCACGTTGGCNTTACATANATCTGTCGGTTGTATTTCCCTACAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAACTGAAAACATTCCTAATATTTGACAAAAATCATCAACAAAACACAAGGAGGTCA
+
01+1C80+(D*&D#5246C2)F!;HG%F7"D'-G%?1',(A%E!501F%CA)?'-B2E8+6"0E6.?:)$"(D,H"'7.%,47"6H&$<@BA42GAD/##,/@3#9@:82(#9"'4,EF='=BE?CB?&4@3#E.9-74)FA';
@r8162
GGATAAACTTCCTGTAATGGTTGCTGTTCCATACNGACTCCA
+
=+&-0)55(1"!/%>>,>$0(4.+:*<?=8E$'8,G7$<=;.
@r8163
TTGACCGGATGACGAANACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCG
+
D3#C@<@)%#&,H(&2D'G%GG+1A+*4@$D6(B/@DG0#.DC>1"-1>37*A7F9.%
@r8164
TGCATGTGGAAAGTCCTACGGTCCAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTNAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATACTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGA
+
C=8G7'1D>*8+C'?>5?'./+++*.0-(A'A!HBD"<,B%/5.361B8E&=/@%>#F&@";-3C323.18/G;:+C!>(8:)%%6=5<5#%;%=DH"=?.:&5<+5GG#(!;=)8>#6)HH2$+6-)'7)0"$,D.-1"9F0@F1)GC6GA>:&5-%8.''!9A@G-89;F?.-2414)ABH'%<**.@91E,18#<.7F4G/!*)#4>D?/+#9A,/8(BH3#)%1(2;:D?97@7A?83G)=H!/+!@H9+1!D/1D,?CC,+@>0.."3.6@8#*H.G(C1"-FH$'8.%!37'>.0->+7#
@r8165
TNAANAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAAACTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACG
+
'%&$$+!($$'+!$'')&)%#++!("(!+#%)()%$*"$!"!#%"'+&)(%#&*!!(!)'%&!*(&#"#)'!)(($#"#&((%$$)(+#!'#'$&)!&*"")(+!+"*%+%&#!%!""(%*))!$!%*)&$'"***%*+$()%(#*%($+*"#)##''#')*$)*+)"%(#'(""&'!)%'!%+*%*+%###*&!)'&"(
@r8166
CCTGTCGCACTCCAGAGAAGCACAANGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGNTAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTNACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCCGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACG
+
7B3@C8:!/F!C%F973CG'CD<*9;3%*>)"G;A/(1GF#'-6&F8C78@-,83?$?=F1-5$6&+1=4B0&>5'@%)<83C");*8FEC'//6*3'2?G.A5B$7<0.('/E%%F<D::E&9@)=,6C-&2.2$B<;"CG+19+*C%)$$AFCD3?-@%6-=E/<%4B$4=F9.6@%,B64<!!F43H<6B*F$:9*$5HC>6(>+(;<$8H@->0&;.<551':*H=%F+
@r8167
GCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTNACGCCCGTTTTCTGGATGCGGTNAACTTCGNCANCGGAAACAGTTACGCCGATCCGGAGCGGGAGGTGATCAGCCGCTGGNGCATGGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGNACTGTCCACGCCGACGGAAACGGNTGGCGCTGTTTTTCCGGGACGTATCATGCTGG
+
6"..%3F!226)HG&E-:EG62=)"%8+>%:D;'8HGA2"90BFF2EB2."A3D$G6G$%@()G%H(;3;/2-5;.@<9(<17!-,(%%*HHG8)08/=<:./!+-*A$@2(&@4&A4F!!G9HB8=.</&(<>&7B?<"FH/27A/=6F:G%&<>+A384-D7/4E1A(;&779$3BAE7.,C=6&56:4:+59E7<E$)61,%@+187<)0!4:@'A#*-&B
@r8168
GNCAGGGTGAAACCAGCACGCGTTATCTTNGTACGGCGCTG
+
'&)&(*())$+#!"$)$%!('!(#%((+)'&$()"!""+$#
@r8169
TTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTTGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCC
+
;@#0,.1<GE0A7'@D&C&""$:5=#-=,+-*395A!EHF6?F46B6!=:/,H3%#,H=&D,0"549:2/'7)G022EA<>B,G3C+%:,!/0*,/2CE0="H.(?-&(47)?2
@r8170
AAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTC
+
C?9-E)/&D0.4!;97/H0EF">#<0@<A=4&;1$A<,)"C)3F&=B56&*/=H$A@1062.;27@"D#HA>9,1
@r8171
ACAGGTGCCTCTCACTTTTGGCGNGGAGCCACGGATGGACTTTGGCCAGACCGAGACTTCAATACGCTTGT
+
1"=2?=-A(H$G!FB.2)989!<=-2<C61$!20$D516A&G8C/:=C,)+":->0C51GFD+621?4$C"
@r8172
CCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATG
+
+.&5GD398"<=%()C9?!*=$C!*&E<5#?+.G1+/?#@2H/"@<74#@?2*2-!,<-0#4?"0G1D
@r8173
GATAAGTGGAATGCCATGTGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAANCGCCGANGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTNCGGCCTTTTCCCTGANACCGGACGGAAAGCTGACCGCTAAA
+
'1:!(B-='$%49.>0(063?&;,5B:5-33(C$1'2*6@9*D44"1?7!#=5/>4.0,H6%!2139$561"499=!&;G44G/A@;0!A$2;%.2+,<6/4%%5E$&-"4CA@/&41&D3!A@"1=0F)B58)+7'DC''C2236'B3G!EH7:0.F,5.6;)4!.",C".;+G-%68:A7A)*(!G<5@($,B1/D)//!8',*'1)+;/+/,68<9"4$%107"')-&-#8;!/,?4B,2+13B7'>+A$/$)AC)19C9/$=;'G,0187,A*+'H3@D*@=3(;<72)AA
@r8174
ATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACC
+
14/)A&1%'25B),3%D*>@$/8;(%A(3*"&(5C(H"40F.;/56F/"C=F*BGGC9F5=B$G4.#D%%A8)$.<<@32&/'=H$*4B-6@.=37D<:6;8<;AB8>F8<D9(4>:>&4;,0(2@.).
@r8175
NTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGANACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGNTTGACTTAAATCGACCAGTAACAGGTGGCCTT
+
$+'*#(!%#$+)"!!$+'+"$'&"&)*'&%(&$"'"!()'(##%)&"#!$)*&!&!)&+%!!%'("%)%'"!%#*')#&(!'**(%''+#'+*+#+*%$'!')!%#$')''#&()+('%+$(*%"$$)"(##)++''&#$#***!$&#'$")$&)!&%)%!!&&#)($
@r8176
GTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGNCCCGACGTCGGGTCTGNGGTCCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATNTGAGCCTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACC
+
CG0<,C?81-8%;#<2?;;5D7""B<8171D0@(D$9G;7:0<;9=!/!1AG0&+!?B3%H;%33?G2AD&(25:-?2=.8?=#F:1>)3#8?6'A0=6?*:B(%3C+>>?5?>7,:DG0;6!))+$B*0&&G2A+$8,3>8&F=>76@6*EH&D(+4C1#;--1"/FHBG&'C>11=F'>2C06/0'#,$:+B8)*3(@9)0E/2+A:802$#6"#E1.)(*G8H$;)#>!$%A?22??.G<)$H&<19'B--93&CBF(@;2"E'/61'D(F!G654'&H0BBB84*)8;F"5;%<93>209*6.&8/3
@r8177
NCANGGATGTCAGGAAAAAAATCCTGTGGGACAGCATAANGCGACGCAATGAGGCACTCGACTGCTTCGTTTATNCGCTGGCGGCGCTGGGCATCAGTATTTCCCGCCTGGCNGCTGGATCTCAGTGCGCTGCTGGCGAGC
+
!)#'$((()+!*(%'$&(%*!"!+*'%$!$#$&&+!#!%!"###!#!")%!$+(!((!'"+%&"$+&%('!!+'$+$)*"!(*&))()!&+#&!"+#*!%&!''!'"*!(#!(#&%*$(+%&(!$**%"&!*&"#%*#''&
@r8178
GGTNCTGATGTGATGGCTGCTATGGGGATGGCGCANTCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGT
+
&''!")+)!++)!#&#(+'%!%'$##*+$&$'+)#*%&"&!!##%)*'%%+'#(&'*!"+(+%!'*!$(""&
@r8179
GGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTNTTCANAAAGTTCTCGGCATNACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTA
+
6@#FC<704):0'!"%6/:$'C(7?#8)+;)5%<@D1:3462*<"F?*+':C3HH5A:%'#H4<+7)0H;85=@0B+'&%7(62F%8*/E@+B9G=*/!-G='<@7"-0?'&!3H4B#);
@r8180
AAACCCGCGAGGTCGCCNCCCGTCACTGCAGACAGCGGGGAATTTCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGNCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTAGAGGCTGACAGTCCAGG
+
-@G=%"/*AB'E'62B<+)+#"71"5<F/#/'.49B5G/A5G(25!>E.@68+#))*292&/,!CF%@3GC<G%.@>3-)7C#(2!E+;C)B<F4A42;>DD49F<D<,6D6*@,GBE9:&FH?CCD)4)6.!<5%,!48&*2<?4=;5):H0+1@*7/&<=C:5=6G.+/2'H%;83!(<62HH3:D4*&?"%8%>F567-('9-3!45"'@>!1FE5?
@r8181
AGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTGCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGG
+
6DC490:,A=,5=<9!C,<,26*/*<60&,.4#!,AG61*<95,)3C67034:&>G>$48$:F)*>E5G90!D&&)5-'C))6E6(F0!(@"69>
@r8182
CTCGAAAGCGTAGCTAAATTTCATTCGCCAAAANGCCCGATGATGAGCGACTCACCACGGGCCACNGCTTCT
+
)G%5:F%/(4.F=3G($/H"E!('CH:/.B@A-)66&?B17*H-$46*D*.A6;+CC8C-<C'76&96!&)5
@r8183
AATGTTGCGAGCACTTGCAGTNCCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGAT
+
$1-F;)534F*$9.H314(;<EG-782?/F/.0"5>"!C<&9+98//@6;.(%1--8:!%H'@,+4!F)=7/B(?
@r8184
NGANNTGGTGNNTAGNNNNNNTTATCTNTTNNGNNNNCGNTTNNNCCAAANCNACACNANNANCACNTNT
+
!!"""$$!#"""$#$#!$!"#"#!!$#""$!!$""#!$$!!"!"!$"!$"!###$$!#!""!!!#$$$!$
@r8185
ACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTNAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCNGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGA
+
-)"<7',88-3;C6@,D245<GFH<35FF?#03D*&H@&$HG"G/A+CD;F:C=*$+?(;@+!2?*%=@&9'=BF1:3:4->!+E61'B<++.A&D8#/*A5-E0>..+;"&>#"B''&!<=&H%<+D+;;*9'8?+1A*D/($3!50B#6-,<#6!*<G;78(6;28
@r8186
ACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAATATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAAT
+
291=#!E8DC2/5>AF70B,C?%%/E24C:,.35!(E&$81067C,D4HF!0*0$@?.6-."2-/;<0,=1G8,7)4"&=!+"8'*=2!+D#:'@##/.H-&;,1C!(H&+'(%G/-&(H5%$7G45A@%'E/H19:(!B9!(5;$6;.95&*>!;;:*!.19&':)@.?4.E+<!E*G36@.230-4059='>G4%7=<):
@r8187
ACGACTTCCCCACACCCAGCATGCATACCTTNCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGANGAGCGGAA
+
6D).%'H84:!/@?(6D!19<*EA>=.%781H'E5.EGG>H8+D42:60<GD?9.035*9FC4+&)2;<H6@/F3:
@r8188
CTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAG
+
-03=5?7G.;+-!+/>F86C70#?C)E,3:C&4+*<4'/@H'9"FB5768B6=9=
@r8189
GCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACNGACAAGAGCTTTCGTGCGGTGTANGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGTTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTNCCGTCACCGCCAGTTAATCCGGAGAGTCA
+
-<)1*D:98.".".G)81'$?(1GD(#2-1(?";70)#H;:3F+BD4?DCE-4#;2/:$81;1?/A!60,80?,E:#G7G'G;+6)8-3A!#G#:..G(7$@$(HBEB<,DF$/:!7C==-*%"97E6A+?5B3:"<*@+$;D?;4@*D</!E2/$@4A'0<B'63&G$#@EFA/$"!::F'"%6E$FDF7/*F/FF6BC74#$>C%$5@/DH4!)&177*
@r8190
CAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCC
+
4,;A(&C,D4H%ACHH<?A5&&6A=&@6</+E*3:>#7!$;$H;F'%A?
@r8191
TNAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGAC
+
#"C5<6!;)+7:<3&C/()=E,=FE=8"@4*;:1"$1"3G?A-8>#".);*@7738'1,<D*3,($+=.-:4HA0+60<BA'ED
@r8192
NNNNNCCATCGCNGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGNCCGCATGACG
+
!#!""#$#$&(*%+#++%*)&$"*#'!%%$)'*'"!!*"+!($$#'#"#$&(''&*!'*))#%##""$$""!"##(*+(*)#'#)%&%")*$$!(#$)'$)
@r8193
GCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTC
+
)D*89.E7/$ED62-B7/>F#2:!?36#5,839'#E@C)1,1:8@H/"%3?@/9=4G
@r8194
TTTTGGCAATATCAACCGCACGGCCTGTACCATNGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATNCGCATAAGCGAATGTTGCGAGCACTT
+
7,</4/%%:!?F05G,#@4;$+9C<9-B;4E.2G*8<(4!D?CG9#F"A<#(+/"B2.4458*/%!G/BD=H,#+9H#)+$A!/?#17G79=0'D039><5%??82F"
@r8195
AATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCG
+
&$:C%)9#!;FB7/2B.)>(;'A-A+=/EFH*);/$'E;+%FD0*
@r8196
AGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTA
+
H8@=&1?%8CG'5G8*+@<C#$-.6#@%%49B2?B6<$+>A!#"#@;/*=F=G82<E9F-BF8"2%324DA!0::<'*)@#B'3
@r8197
TAGCGTTANCTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGT
+
4;G":.$#HED*>?<7E@%29!*%6&;B;35@$%?32,E9G;0=#>06:""
@r8198
AATTTTGCNCGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTAGACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGC
+
259!F2?)&/A3-)),B+6;',+';6G.@*:69F,-?/H8G4E97"1&&FB;($='"#0#::>85&C-+)62G9A7-+2-?/E#6"-F?&B;+6;"@%)7(&+6-"4G!8-<E56D1D)7)9.(C;8476B?*-02:$G0=4BH2";G7B8C&6(AD=E/'#A;7G1B32/)5D*<@607H
@r8199
NAAGGNTATNTNGNACCNCGNNGGTANCAGCAACTCACANAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCNGTGAAACCACTCAAGTTTGCCAACCANATGTATATCGATACCGGCGC
+
"$)(%!#**$$#*&*#%&'))#"*"%&(*&+%)%$!%&'&'$*&)&#%*%#%"&%#!(&#(%()#!&(*'##)&')'$(+(%(#&#'+!)&+)(#*)'"+!"#!*%%"%+&#$*))(!#!!)$&*#*+!##($#%')')!*!)!#!'
@r8200
GAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTCACCT
+
:<%,H:H><@&H4G<'.%4@1<+.E7+#2,"7#:1-7EB!C*'B.*3HGB#B==&3%68?7!/&+1E;:C@BC-(@G218*+8AD8588-24H1,D@-.
@r8201
AAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGC
+
FCGF*E2(EB7-2!A=98C@:96!H(!%H?1)?*<1D09BA=>80%A17=1#:#H(B2CD59"<#A:*
@r8202
AGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTC
+
326(+3."=/57@?F?GCCC/"+=,*<0B&F32D!#E!145)H=$-F-?2FA+D%+4)/53&1
@r8203
GGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCT
+
1'7$<?C5''D+@:(B>37.)7*6,,%8&3"B<F.44)'.A0!!:=2<(@@@8@,/,=72HD3%(:.'=!:F314."4".
@r8204
TTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTAGCGNGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTNAAC
+
)A5:B;66%.@>45"B7)?,@?>;5EG"9:D&?#4$>7*,2>/06/=9,2D65-(0F$F"CF=9C9;#B@?+$D6+2#&F.%';5G<CEH&3/9*@9EA.0%9E<AF(HGH52A35F;#3*9;D2HD8
@r8205
NTATNTCNCNNCTTTNTTTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCNTGCAT
+
&)#(%%*&%%$*"%'%!+#%%"+'!!+*(#&)()$'+!!"$'+))$*)$$+)"+#)*$!'%((&+'*&&#
@r8206
NANACGGGAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGNTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGNGATGTTCCTGAAAACCGNATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACNGGAAGTTTACTGTGGAANACGCCATCAG
+
(''$"''!"'+(**#'("&'(&%$("'+$!%$(+)!%)&!*!+&++'"$%&))!)!$!)!%#!($*)#)#*#%%+""(&'&+"&%*(!*("))'$+*'++#&$$)#$%%(("(+#"(+"'))++*(''"#$+$*+*(%*$%#$'%%"'%!*)#(($))"#%+$)&%%(!("%!(%)**+!%+()(('*$&&&*$#$%#&("')#!+"!#%$%)&#"+()'+""'!)"*&'%+(*'%))(+!*#"*#*$$*&"+%#*'%*$+)!#'(#!))#&%%%(*%)"&"$')$+#%)&!!$)&!%%+)(##*"!!''*+!)(""'%"')$$+'!"!+%'*%"$!*&*&)%+!!!*"#(+%'!$&%$%!*'&')#"*'#"#$+%&!%*)$((*%%'%+""#&"&
@r8207
TCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCG
+
>DE4#/"'FH;"$@#H4:*F-/5!06=<,'2"&9D2?);=E87?.F52:+%*?
@r8208
GCAGATAAAGGTGACCTGCGNAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGANCTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTNTGGGAAATCGACCTGACAGAG
+
1H95EC*G1<60B%27#9#2294%HH)-@@7D/(5<6,=G(B;.3,@/BC&!41FF-*'=?HGH<D%+;6!)9=.*7<A:#:D(*A2%:#,)&151#?&'A.34BH43"58C',.01#<A."H:-$#</14%+!G"102*>-C)H)/-4''?)C'B8B04&1#<24-=BB:C?:8@;',B
@r8209
TTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGANCCAGACNTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAG
+
-;?EG;-."3A/B-:D(5%',D=7'E9D'=9#*D%5E5&7?&>+-7G;)4A&7+$04EB6DF<>A'D-+$)=57%**5.7;>0E/531()*3<%,G+9FF9-<>?<,D!!7DD%EF1&:3F*9AA+(C6)%!+
@r8210
CNACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTG
+
"%/05A$,;57;=1)#!)'B?/E-'C@>&D*93>%*19B0.+
@r8211
GCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGT
+
GA>56;B8#.GD<CA8EE<'<6$9$@>->3?;5#/D<,,H-(;GF($#+&/*6505=%07
@r8212
TTGAGCCGACTATTCGTGATATTCCGTCGNTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAACAC
+
.,(GE+<>3DD4$,>"A)E">+!H@HG'&''7C8F%?GG;7;78EA2>+10=A"'EDA0<%&+!;
@r8213
TGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTNTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCAC
+
G=7H)9.+#72$0">AC26#63F$@&2=#E*+<D#D:@/:.14"8+!FB?/AA(D6C<>>'A93+00'F+0.;>>!/057,$(%0',3@:35G*C2)2H</17"G2D":=+0D24FHC@BC?(+=C#'D#2B95/814.
@r8214
CCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACC
+
'+D?C+6$115E:7+):-F0H&2?8FB7(/.B"D:C5/B-)+=,(2<25,.5@BF:"5B=6:F+.?F-*C0
@r8215
CTTTCACCGTGCGGGTGATCACTTCCTTCNGCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCAAGTTCGGGAAGCGGATTTTNTAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACG
+
$)%+%+#%%%!$*$(*$&&''*+$+(%'*!"#&'$!)!++"++"+!%*&!!$%#*)'))'%&$&#"#+###!"#)&*+%&$'(&&&++!&$))+%((*'&'&''!&$"&+(%+!"!&#"%"%(+$'!(+*!*)('((()#'($$"+*)++"($#%$!&$#+#('$)&
@r8216
AATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTA
+
=.H.%4,.8=A-;1H5='@2&0/!#3D<)26!-+;,A2*?/;"9.E8*=(>A%"4=>='+?8*47&'5!;F#H"F?F784$;@8DH.)>>@/1?:D&=4>;:?-*7@40-=8$H+EC@+;%<7>*#<,#82(@02%A@@28B&<'%DA(/*6&&*=#3269=HG*69!+3)@,%#!FG054E.-!#=*+5#4/37271?<
@r8217
CACCACCAGAGCGTCATACAGCNGCTTAACAGTGCGTGACCAG
+
4E(,:E6HD!EB"!.F9=**EA23@.&$3E?EG:/,E"+>*.;
@r8218
TTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCA
+
/=8.7D1$(?796DA4=2;B>@(E@!)/34#!9"-2;C8/G+;++*@#E
@r8219
TAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATC
+
/(*)H/=C4<4;.',2;86FED?;'*.53-4EA8!CF(&.;E0-1B#D.=<8>4930)":!/H5>CA+G984C5,)=,E8"F=B61&8""++E+"<(B:3.=8C87,"?)A926+$:5:)C;.,5A?H?&(5GC44869E;7)
@r8220
CTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGT
+
3)<@+<!+06G/C;<'55+G&&5;#5H$D-5<%"+=DG.*H.%-'G+#H7C6C!;?*+29'-0653D96#$?@'%14'#%CC
@r8221
AACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGACGCGGAGTCTTATCCG
+
5%%+H4#A+/C>0A(!<85<&'9HD/1@?>3>-!<"B&)B#!EF","%G;2%1=$+F/+.-F9:%B$?=E=0<@!43.
@r8222
GCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACANATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAA
+
31$<AEEC-C/FG3%<.1=<)*=7#7%!%254"66G17(,#+"'-=HA1!'3+B7@:%"9=B>@7&1+"7E@:2+CD@%&5FC9:5<<2?7#76!
@r8223
GGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCANCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAG
+
B#0CC9/>F@8*<:)H#+DB1$D94.9/3#?/:0"6G9=.?B2?%;$4GC(@@B$5.#>3!/B2D>'9H#'@'+%D."A.;
@r8224
CCNATTGAAGGTTCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCG
+
&*!)%+("'$&&"*&)**$(+'#$'')$#$!"#%('%(+#'$*)$)#+%!%$''
@r8225
CAGAAATGTNGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGA
+
?0"&2--GF)1"BE6AG,-.56*74=,B?%7$G7E/2@C>D8:&.=C/5,#-
@r8226
CGTTGTACACTACAGCCTCGGTATGCAGCACAACCTGCACGGACAGGCC
+
DB3A4.B>>C(@'C?D'A%C7>>2?&D0>.$/4>'+<<#2#>87,E8';
@r8227
NATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGAATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGG
+
".("3(">1%9!='#51&A>+;&#CC.(?7%,>74@/)90C3#3"1B8>&?253B(58C#6/C:"/2FG(7$F+0'3H()B%!A1(22?#>#,G0-%-5&&2@A4/>B(2.*'@@7928GH9C2=5A$77B',:GF;7;%1;A(!%?&;5B99GFCH$-!/)//(8!!4!<-D&DFF5>E$0A>!,&%,H$3F#(,%%C;/=/B8@GE0"%B=DD9<H:E&8D!,@%AG)-BC?*#:=9.8A.@68,*C
@r8228
GTCAGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTAGCGCAT
+
)4$A%(3*8,&58@58%-?.$2HF"2.4(CG1"H6D8,">")A?#0'7DD5:5=<F5+3<?=G,E78-BA7@B;?4A5$-H7)#CCCHE3C&-C@5B"E=$::@9C@'%5&):AAC:+4*(&DD
@r8229
ACACTCNNGTGNNNNCNTGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACA
+
)("(%*#%'&"$#%'!#%$&+$#&%"%"&!&%(&&$&&!)(&)$$$+&&'!#%&*'!!'+'!"'%"*&)&'+!"$"!#++*&#'!'(+("&!%+*!%
@r8230
TCATTACGTCATGGTCGATTTCAATTTCTATTNATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACATTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGA
+
F-"D!>!(D'14>H,7>5@:)*/GD?H+1H>E/5/)(?<+9/+5-1!3+:13B,&,41+7#4':2!A(#H.#=-*5D"'0)4F3!CA19F</4G+/*'<+--!%A'F9*3>"G'C-17CDG=+E:/&(=5+E*'4>!CAC?!45$6"7=.$4BF(;+2D+5-B=2:*.1E-812A(C3C3+272,!<45-G%6'#.)#8'*/5+,G""=
@r8231
CCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGNAATTTATG
+
4%?*7<B&@@B+"$#04"5G<?:2.#?B>3554A$?)8CA?H$1!<DHFC8>%D5';/#5G82,&$>0F0,9>0,H>+,$&+!,E!"0(E);E
@r8232
TTGAAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTNCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCANTGTTGATCTGATTAA
+
=!8A9"23)-2+7G-?3=;H:,33C097)1$+#&/4&E?*#'51()&?)5=EB!1%77:/:@@?9.7:*8,1,>?&*,<8.<G3,%7&5#(,7:>!H&*A"!-4F4D#F)6@=?+EC<9.C7+H@C4A+/5(2$BH@5/):"E>G@1.6":A#,&12A)19G9C7;09?/:0/"5<+!6+8<<D
@r8233
AGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTTTTGGGC
+
?=1"/,+8A=%@&/'+1D"C.0.+.#$7,H),=5;52AH7=$/0G$
@r8234
TGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCTGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGNGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGT
+
??4B*67=3.+(545.#"=H9A'4</(:6%"=3?.7*0+82D*C$30'AC@00/'H<@+E=<*82C7,(;H)1E"-)?->?>.!.&*7)!<;>F(,=#("?96F:3H38*?'.F$AG)/@<AC%27.+80--E&*3>&/C;8!1+
@r8235
GCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACT
+
$GF.8-?%!1:+G&&><(+:3"!AE##/&2=,B&:68:#/-D#B=1A?90D+++A9CH!8;DH/G<)5(46CC;0*(!.)25<?$
@r8236
GATTTACCGCAAGGACCGTAANCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATA
+
'99E7F-6A8E@?H(@7/%7,E"@/E2HCF28*$'&B>6#:(9@<<B"@=):0!!>!2-;+;110G07">+H1CE?>:73!,H2836'6G5)"&.0>F1##=,2H9,%@>!F&?+5/->>71E2%H?>.<.5=;A90@A7
@r8237
CAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGC
+
%H/2@B=F?E-"B-2?*A2G!7@:2B9<;&#F%)%5%6C4"H:A&A72"
@r8238
GCAGTNGGCGGATTTTATAGGCACGGGTACCGCCTTCATTAAACCACGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCA
+
$&!*"&"(++$(&&##")%%$('*(("+**#)#*('$!+%!&#$$'*+$*%!*&!*)!*#'("#"'+(#!+')*%++&((%*''%!%"+#
@r8239
CCACCGTAAACGTACCATGTCCACCTTCCGCACGGTCCGGAGTGACTGTCACCGCAAGT
+
/D,=H6@1>,-#03/B@2/%5.:2;CH$*6/'=$3'#%."=3(!@AA1*+86;:G!.=@
@r8240
TGGATTCCAAAGTTCTCAATGCTGGTTGCTGTTCTTGAATGGGGGGCCGTTGACGACGACATGGCTCG
+
28:/>:D2-6208:87&<9$/,8>4E<1/,E#;=$HD=#H-;<"21(7>C)*8*-$#3FDH91*@*G$
@r8241
GTNCTCCTGAAATCTTGACTGCCATATTCACCCCACAAAAAAGNCCACCGGTTCCNGCGGGCTGTCATAACACTGTGTTACNTGGCTAATCAGAATTTATAACCGACCCC
+
%!+)#$+"*!("!%*&'*""!##"%(#+'!'$++(!%+$%*'*"+(+#!)(('*"&**)*+(%'#(+!"!&%&!('*&)"+')*#!!)#$%&*)'&*&'"&*+#$&$'$!
@r8242
CTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGA
+
=?575!.A%D9%.!B"H@#:(?($!10'>;<,&60#>)499G%BDAE8=H!/F'C!F*#9>,=1GB9(/9A5'7#1AA.'-B:D:'810$&1(+/:E!58/)/2<.B=9
@r8243
GTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGNGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCNTCCGGCACTGA
+
-B4F4G<@&DG#-FE13?C&.7!18,8:B'68'64=?>>041;;;/"/4+)(8*5?0:6=*3#F.9<118:;@?.*(+D*D;/,,D0-=E?)3/%(*+')<+E>#B".@B/?'$3E5G5=3-*9>$67@
@r8244
TAAACGGGTGCCAACAGTACAGAAAGACGGACGAAGGGTGGAGNTTACGGCCACTTCCGTG
+
9&7C5&#*<)7G:/6)1";F**G<B-.@*.H/*BG*"G1/='H>+$?#)0B>8E27D?"C?
@r8245
AGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTCGAGTACGGTC
+
*(21719C2+D<7<2"9=&4>'8!#;'+H+;"(5$54*=')?1(<*#6/*@A@!);-=>2<301:7G6D*722
@r8246
CCACGCGCATTTCCTCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCNTTATCCGTTGTCTNTATACGGGGAGTTCTGGCTTTCGGTGCCAG
+
3,5C'*!)53$<9.=43,0%F".&109<.<;A+A!&.=(=0'79,>$)?8.6>6.'GF'+81<&8@1<:?),+D,0:,8:*HBF*11!@48G(1GH8#CD,%5@90=!D13(B>-D.E8,-54##*$%!H#:0
@r8247
TGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAAT
+
/.!E378D)%.&('#4)8.:)D>&9-C$/7-";$@01)A2G(!!
@r8248
CAGGCGNCGCAGGGTCATCTGCNGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGC
+
=$%D4$9*$)--/F7;E3CE5H6&%','1D+-3EHB7=/6+A;<0E!C0!"+431$0C=776=*E!(64F:+*:=%-
@r8249
ATCAGCTGCTCAGGTCGCGGCCCTTGTGANTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTC
+
+(0::*.H1%G+9.3:##?2*AFE&!@;:."%'C>9'1-6'6<#.3+:)$6+1G?F8>,"?');!.0?6!G.'(+%-(C74$##;@!1<.#<63:E&<#,<$:FC
@r8250
TGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGG
+
%*?B6"E;D55@12/?:0'8;H0,A2117CH3%42%4,+!568C6'0;>C3E5.=9GG.#0+;B'-(18@94:'$D$1!/<<B++9*1%EH&)99)3'-,++-?A@6"%99>4!E$#1G(%E$:+:G%*E.);$0!44;C,4:<"
@r8251
GNCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCNATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGT
+
"%(+"((+%%(%#%&'#)+!+*&!&+*"+'&#&))+*())#"+&#*((%$*(%&$!"$*&#($")#%$"((""""''(%%*()*!*(#"+""*%'+(!''!)"#%**!!!"*"#((+(+*(+"#'!#&*!*)*'#!++!#'+*%#)$''%&)'&'(%"!&"#""%#(+!!*"'%&&
@r8252
TACCCATCTCTCCGCATNACCGTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCANACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAA
+
9$C5!F!6=G/@?-=5&9CF:+18?<3:F,5C;#5$'#85(,H2-H*A!.?.$9G3@)B6?)"H#H8#-F?H%,G/63@%8;&=-$.8'!-=BH>.2'4(11!/H376<'?%?2D'728-80CB'F48%C>4!;1E'$'+6%"*-!'.,=>#&H<H+.G(E,B@3"6<6$338E;F>5#*
@r8253
GNGNCNCNCNGNAGNCCGTNTNANCNNGATGNTATTCNANGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGNNGGAATATCTGGCGGTGCAATATCGGNACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCA
+
&'!($""($!##*&#$"'(#*!(!'"#%#')$'&&%(%*$)&(+(("*$)')*"'#$*$&('$%#%'%##()%$()&!%!**!'*%#&)"'*#&#&'+(&!+'&!"$(%(*&(!&#$#&$%("%*()!#%'(#(%#*%*""!$*#!+$+***'&%)(%
@r8254
NCTTTNTNGTTNTGTNNCTATNCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTGNTGCCGAANTTTGCACGTATT
+
')))%%'!('$#)"%&!%'(%+%!%%*$)(&"$!!+#")'!+)&+!!!('*(&(!"")%&)'$'$)&%$+!&*&#$''$*%
@r8255
CTGGCTGATGGACGCAATCTGAGCCTCACCGTTTTCCCCCGCCTTAACCAGTGCGCTGAGTGANTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGNCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACC
+
$F!"4FA.9@%'A?<7*9>.(=:@)8="79@8@H778"?5A)#H78.0=AG'3#99!?"042,@19&!$.#8?F6A*2G"7E**:&60H/BA#F'H&>F2B6-)A-1C6",%<<H*"7/@0E,9-$G0@@*<"9.+0A+E/+-/(F'!)1$.<310-8,EDG@
@r8256
TTGGNCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGC
+
%"'&!+)!''$&#+)"'$+#($+$&+)'(#%+%$%)&$&*%'($!$)'*%&)!#"+()''&&$!*'*$(*&&"+$*$!$+*')*$(*)&$!!
@r8257
CGATTTGGTGCCGTAANCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGGGCGACGTAATTCCATCCTGTTNCTG
+
&+%27<3D8#"G%$,D,8)?#,+)&2."H'),=@:E*:6A+1)6',$DH(?:HA1C/'9>H(A5437'&5=+8375D*42?=<CH3=H7<%7:FHF%@3E?/7*/H#=-3F'61(01>F1H3;<6'$A+?79
@r8258
ACCACGGTGNTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGCGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATT
+
;,GH&1%$$981(:4+07?>C6)7,:6&4ED,+C:);=!2@-G;<@9.C3C;>3)<4.!118!<+;@8:*;#9,828B?CF,>5;F74$9,B*D:;>+H"6@&.!+GCGA$50A6;HC</@F?+E/8#41:F<5!'?:!2!<1!:)C&(:=
@r8259
GATNNCCAGACGNTACATCGNANTGACCAACTAGGCGGAATCGGTAGTAA
+
#$!$'#&(%$$'!)'*($)*#%#+('"##*#%!"(#'(!)&)!($&*"&#
@r8260
GAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGNGCATTTATTAAGCATTTCGCTATNANTTCTCGCTGGAAGAGGTAGTTGTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCGTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCCCTTCATGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGC
+
;91)9&?#?//6B6H!**6;G<@16D9G?FE3'=(B<(2"2679"8<#8(3<',>+4:#H=<2C4/:",2*$(!)F<%C=%(84.-H/<<(.'.%;$3-&"E34=$EH8@66/(<G*7%A9@AA)50/.!22'=CAD!@D5-)#?5<920'')4&H$.9'*?C0'*8<5!G'?,6#5&C--E2'A1'F$A:;"+2EH'05F"2*'$@+FA/@!@(:%899F&&=G'H#)0)F%:FH+D/:@7"%86/2>&$9G7:$?GAB;@'#,>EE)/&?!B))C?5,CECB>''D-?.+-!31'*7-@@D%4'%3799C3<:38+66#C@90?(CB>'*G@4&)2$F/,!@9""B2>507$DF<7A($#--?1!+0>5#
@r8261
AGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTNGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCT
+
=@-1/4DF0=+DC'A1=A(*:6(*>A?.H9;))C#*';7+6">&CG5*;H;0:+)GG(78>'30F@D/=",E274GH","92G*+'?:9.;GF;1A>8(31B'-C?3*=8!4GF:
@r8262
GCATTTTATGCGTTTTCATGTTGCCTGNCCGCATTGCGGG
+
'+&.@.)4@0'')5FG()"(55$!7A&&+'?&-,04D'AD
@r8263
GGTGAGCAGGAGCANACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCGTCTGCAAACATCGACC
+
E<082%8+CF$3=(<>C*1,B!82A3:'??H"+:/44%3,(./-+17$E%#D58C';E)'H<=3G:%'715@C#5#A-.5$!!#@@76A857A&B=G.(=4!1(%,(9;@90F;98GG0B7E5
@r8264
CCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGG
+
1##75)&,4"669&0.9/G+1)0<(D3-4:AFC3"%>+92G6/;12%$)!<5.68
@r8265
TCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAA
+
0BG>;G.?+(C.HB>&:9!*B(305F/"8=E)H:#A78/98-8F<F,F.;$(+(+A7),)7G*1C,4=0(@D'(!H":,)>:8'8.*/$G3&('/6)2F#CG@"<1A7/
@r8266
TTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGG
+
8&6=&$2BFG.1C0/DB#=?/7***8#-8ACE7H!16?7D?G341/EB9)3%103H%+G.G=5A+8E:>@8>:=E<B?3/:3B<"0,B0D0D23.,-.1%D+0@4=D9$<=44%6.*#4A3@+A+?8;)46D&<#+-(&1;D+#C+C*4+>)HD&;C6673?'H@348)H%->6
@r8267
CCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGAC
+
3)#'7$>1*HA31)$&84'<:6(?!(1!@!E4.B*1(88%$*5=:=0,DGD>1A>/C8)/9,:$<%33H%3>A.@!@.,1:&DG,0#**;+E96=FF'.B$0%<&!/.7C@H
@r8268
GACATAAAAAAATCCCGTAACAAAAGCCGCACAGGCGGCCTTAAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGG
+
DG/)/H@6$74#A78@/83--?!?)(0%&'>3:A&E',))8A:3$!76,3C?06/4'0.B#-2>"/-875+.*HD!FA4CA<@6G/
@r8269
AATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACANTACAAATCAGCGACACTGAATACGG
+
8?A'H+F0A-%'0A?*!+=,))#C/!B)-",*$F9G'+3EE(;<A9*2"93$!@<#E@:321619#:
@r8270
CTNNATNTANAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCNGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGA
+
&$"(&!$(%$+&+"""*+*'&!)*#%%)"*("%&&))'*&##++"%&$#''$(#"&*+")**!'%#*%+"!+%'+%"#&$&&##)**'*'"%)(&&&'++($#'('()*+$%##&()"(!(+!#"%!%*($%!'*"++*'+(((
@r8271
ACNTGNTNANGACGNNNCNNNNNNANTTTACATNNNNTANTCACNTTNCTNACGNCGTNNCCCTTNGAGACCCNNNCGNNGGNGNNCGNNCANNGNGCNGGNTANNTANGNGTANNNNCTGGACNNGGGNTCTNANGGNNNTNN
+
$#$$#!"##$"$##!!"""!!"!$!$!$""!$"!"$$!#$##!#$$$!###!$!#"##"#"#$"$"$!$$#$#!""$!!!#$$!!"$$##$!#!"$!#"###$"#!#"#$!#!!$##$""$$"!!!"$"""!#!$"#"!#"#""
@r8272
GAGAAGGTAACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAAC
+
H";/.651D49D/!<;.<&)3E.B"1?@@HF01B50&+0C93!(.G:8!;?<D8;=)F?>@:E%AE>**B'<%-=(-9*F>:2&@+@C;&99B6&=7(7#4*79*9!&*
@r8273
TCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGT
+
-24:#?E6+'66H>GH#63E13A)+,9AA.%B2C%B4?G6E123CA8C2:>"*(.0!(<<;BHG=;FE9)@6=G86E./1BH=-45,82!D=:1G,?=1>/B
@r8274
AGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCG
+
*728D<)@<;$*=0)?$25:4""+2-82$"84@#E=FA+(E6%,A)D>32",-F278<3C6)&&$/
@r8275
NAAANGCTGNAAGTTGCCAGGAGGATCTGGAACTTANCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAAT
+
(((&"")&""&+)''*&&*+'&%*++(!!!")!#*%!++&%'*+%!%!#'$!+!(++++(!'*'%"#+&+!+($)&'!!#&##%)'*!#"+#$%$+)#!""("(($'(
@r8276
TCAAGTNNGAAAAGATTTATGTGAATTGTTTTATTCTGAACT
+
)"()($(#+*'&+!()+#%*)+$!'#**#***&$)%*&#!!'
@r8277
NAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTT
+
#3>/.E)&="1<B%G0F<><0>&9$&:.>C.F*2'H#2/*GH:#0<7,0;7$$*9<@4(G>E?4-?HB!$@32
@r8278
NCCAGCNCTGCATCANGCANGTTCTGCATGATGATGCGACGGCGGCGGTACGCCGGGTNCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACT
+
#*"*%'$&*%)(*$'##()#'+))#&++)!()*"+)%#+$*+#$%()#%(!"$)#%*%)+"#)(#!*)&"'#+&*#*'$+$*+'%&&$"(()!(##'!%&$"$'(")&(#!&&'%%%
@r8279
CGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATATGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGC
+
4-2-D+#%*%1%1)G">6F#6!)A83E(,E>3>=%9F96E'?$,,(*D.1@(8+=@&E"<@E$5">;)0,7.<$+)1;@6*!C#698G0;@(E+DD?E&D,C2E!9;!(!0E:'@,AFHB@;-,0C+@(-#H=E32A=+9$H6=03,B1.'1D<C>2:@%;+'G7.HH&#-=-.)9!HC.0-"FG&0B80B
@r8280
GATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCT
+
>5A2,D'816,!FD1$<0=A=@0E0*#3>(;()'(B/8<G,"
@r8281
AAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAA
+
<<*;?>*.@->#./$B-(;*&=%?4.8;8?#H>5>!&;;">BG1
@r8282
NGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCANCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTT
+
$,BG<-'>2H+6"%)'6%4A@)7*4B:*3%20*118(9F"@=(H**,%",'9=B@A-#)12"B(7G!,@6E/6*AD%7C)4&>@C?2""F?3+0;BD7%64H$,B7>;%AE+1!:G6<$2'C!9,%:!6*;953#&"A?C#&D(E3'/%H;
@r8283
AAACTCACCACGGTGAACAATCCCCGCTGGCTCATANTTGCCGCCGGTTCCCGTANATCCTCCGGTTGCAAAAAGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGNTGCCGATACTCCCGACCATCCCCACCATTGCCTGCTT
+
;8E*#C9*0=:E54>G$-?E>!/+?43=#5)'0"-2B=@7,26:A6!52?-452C4A$%(&*%':=8!)B=E'C3E$#,E".C21'!A!&A"0;@8D*.3)-<B?/'E.<@:FE=-=-2#"9""93"/7';6'$C#6+($%)E:0<09&&/:C==5$=D)?GH'.+%%9F'!97G??,5=?.>DC:<=@
@r8284
CAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTNCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGCGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGATGCGGTGATCTGCGCNTTCACGTCCGGNTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCANTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTNGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGANCGCATCGGTGCTGTTAACAAGTTCA
+
;>C04@B,HA=6F/AF"D#!9>/#EA'5&:<2458<3"+->:=E7FB1<F3"<@@/143%)".,.1!)B<,/.;<%C"0@A.G2$*,)@"88)&?@3!+>:16,&8/4F83<#&*&EA7"*?1945<H"-01H4)*>&(H8?*-3"E73$4E95:!*)"G%8&!D2(DGD8@E37G>H<!-+4%@!8D0"%#:5=D9.8%?C;5)H+C!,0GG58811,)E+$>?A*+H&<<E64G(1>4E;+@"F%:.*@>F*@)'.E'+5.:48<9>H'$%=(9@CG0371.+-959;27?956HH6::-&%.3#8)A9>.@887@A9=G82)7344H81&6D3:)&!6F>?B.3A+%G>@:,FD='H-03"0.G;)3:)+F)C!(%2@#ADA'D)/9'3?92G:
@r8285
GCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAAT
+
,2?81"<B"!7!7)F$@:8@-E<)'/;3!/B?8('#7EB<0)#180!%=3E
@r8286
NGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTANTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGANATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCT
+
#28%5AE+&4>2!@=!=.(!%(0,37&-3FFHH2;:B%G31:1C6E);G?9&,#7.03&7)=$-'<;(&,+%$.E<B')B)<-95/3<&(1.6*37(597GA+?8?'<1G3">::/=74.*!/!/"C<**=A/37'0;H!G*;,F@5#''?<.5B/)2*#AFDD3"BD4!10>62>B50;"B6H+370$"D<$:<,7;/?%5<.7/6F!.3'F(/#):2*BC!$;'6E;>.B437$#A/'B?@#9:*<34,H/?!>'+%+*/@6C>)3:*8+FG6C?
@r8287
ACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCA
+
9&<./)%:)<4$7)465@D?;/!)&'E4'#3:2D:>>%&1#)':C2#0=0!1C<%3,,<!C$"$<,>76C(,4/6*.,;?@A>8.9'6F=#&+EB.7,7B)?3**%<-=.9?'D69D7
@r8288
NAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGNCATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAANTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGG
+
+;(>;:%!F+*:0;3+>4,)9!/(<B!":5>A7-;<,/4'%'A3DDE8&&@$#&5GE0!G$!,25?7:8H"%,C;CC!'2=#@4;+'F8%B)"F)4B0G3@8.:"C1?>1!%G0.;"2;B'$#/$-0@9HE,F!$FF&-#(.+=C39;FD:6C%$/#H-"2:A/E+=B*9!0'<.@,E!'$7"0;1/CH4.
@r8289
CCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATANCGGCATAGTCNTCATCGCAGATTTCAATAACA
+
%=,#+91D,-B*:-.0>!+!6'1564)2CE8!05D='H?/1EE*=>C>9/A2C<D.:#:9C@6>+H,'0;<1%7#5G2@B=!<&A9ABA'#)+5+./;201;:C&D!=-C$<F,'C!(FD@D$F&(.&:G&F,.5'"?B99.),#C=
@r8290
NTTTTGCCCGTTGCTGCCGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATNCGGAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGNAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGC
+
'<'6/##92)*::3@/=;.2B)E;!-G/1#.DE0;(28);;==@?H21E;39%(2>=>!6@+-8+8*'1&"CD8:.0,D,4F@.);A1C>,B;1*-73-FG/09%<&HFD>:)2?@/F(?;62,2B)?5B:3&(>$E+E$#/?8&-)#)'5+3'17/%$6!?E7/(;*0507F22
@r8291
NNANCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCAC
+
')8;>+@<=>>$$6(A6DG17B05CC(*H%&$E"0#.C(;7&+3A)@29HBC4H;1<%#G,8'@;#.HA59#G5/76F'>DB694H,E0<(F75!*(3E=A7881!G$&BH'G(%C5-2+)A6HH8&@&%.&'-(E>5=
@r8292
CTCACACCGGTATCCCCGCCCGACAACGACGNCAATGTACCCGGTTT
+
3-<,*":6:#G$E@H$<+>/6)&E(,EDC,8.=*?A/F(AD=G"C:C
@r8293
ANAGGGNCNTCGGGAAAACGTAAAACCTTCGTAAACACCN
+
&!*%*)("%%(((++'"+&&%%%*&(*&++)+#(+'$+!*
@r8294
AGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGAT
+
$B#=G,D2-C+'F/!-#>>D&D;;=*=G(.F')9+:+19$*&DG,#EH.=)D8
@r8295
TAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGANTAGAAAGCGCACTAA
+
651'3",7$886&9H@)H1E++2)9=)A'37$4:818134-2"#12=58$*B0GF6,2G
@r8296
GATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTNTTA
+
3?=.16$DF$"&D"806+,:%@DF3C##D*@>*%.(0;H8
@r8297
CCACGCTGGCCGACTGCTCCGCACGGGTGCATTCNTTCAGTGTTTCCTGCCGGATATCCTGCATCAGT
+
E(C2"$:>"*?2@%!*,!93-</$A6>8FF9D?-$7)=E)@A:"@"B+94?91C(#1"266/3D$:;,
@r8298
TGANATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAAAAAGTCGGATCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCG
+
"%&+))%$"%#(*"!!#%*($$'(%&&!)"*++''!$*)%*)"#"&#&&%"++#++*$"'(!$'+$#($+*"'&#+&"*)*"!)%'$$%##'$"#++'%"+*&())!&$*'!&%)"'%$'$$+)&++
@r8299
CTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGA
+
F<=,3=6;:&E'1+EH2</99<GG9EAD9/D1.G;H)3&0C&78G5>(FDFD18:#:?9.C2HB5$6E:-@F%D.55',B)FC5%D$&
@r8300
CTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACC
+
3)</>A"E.#=$G(2073@)#A*(36*9&F:,=3(0929B.F0*G#(4-E56;'@<691@2A#&@)EBA/-@=C>>5-4$=(:HG8#D>
@r8301
ACCGGGATGGCGGAAGNTATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGNAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTT
+
2E3>5'<-@*->3)7#6;*D@,54'(#;B&9=93;367'&%5:*;?$,(:%18@<<!/C/6+998,,E";!%F&.,8D*F@5#(!'G"?<0%(&.E,8'9B%E'G9%@"9AD'632G>=>?<<E$F-FACC+-%*0+1>8+G?3<G'>'0734)8-80D/=+5A909G@&<;@/$(C;EGE)".G53H'>H2@9,*C/8HG,0A#G;,$8B6;HB&!%#'BEF&1
@r8302
CTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTNCGTGGTTGTTCACTCATTCTGAATGCCAT
+
F;0=C<)&1#5:%31A->;*#>1>>FFD:0)"2?*?!1)&&%>'B.=%&:6#C55B)"@/G0CB063G3'+?@D+?198B-D
@r8303
CTGNCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTNATGCACGTCTTTACCTGCNCGTCGCTTTTGCTCCATTAGCCA
+
@.">D"-?)1#>=;ED.D++;%5'A*.A>)5"%0H+EH@D0"+$>CG-1:3BDDH/>*HB"83,H3C#C9HE-/=B>603":.5<0F<D$%37!H;HG2;A<'#=4).&?5@)!:(A6"=->8<;17:#CH,@%49(0)62%*).27/<:C&9)734!5(D?<5.
@r8304
NATTGACCCGNACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAANATACGCAGGCCATTGCCCGTTACGGTCGTA
+
"$$+@98,9F.0"9@B542@&6$'3.&D$7*/D?8+';-A6B0?>-#@11G1!2/6065+C0F#:--B#C.&$)$%H
@r8305
TGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCAT
+
8+!HD?=<"=F7+:"0B&94;.H/A?BDD1@H!%()/2@$BC'3A21*7
@r8306
NGGNNACNCTATNNGNTNNCNNNNNTNNNTGCATNTNCAACACGTGNAGAACTCANNNNACNAACNTC
+
#!!!!"#!""##!!$!#!"$"$$"#!!!"#$$#$!""!$#"$$$$#!""##"$$#$##"!$""$""!#
@r8307
CTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTC
+
3-H:#.?'(.F2?'H"E3;HC.E84>7B;0=!E/F!AG6,/%?*#+940";BF,,;B
@r8308
NGTGNTTTCTGGGGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTNAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATCATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCNGTCAGATTGAGCGTGCAGCCAGTGNATCCCCGCAATTTATGCGTTTTCATGTTGCNTGCCCGCATTGCGGGGAGGAGCAGGATCNTAAATTTGGCGACAANGAGACGCC
+
%*%%"*(")+#&%((!!($(%"'+(*'*)%(++#$!+#""&"***$(!$"#&#"##('"%$&'+$%$%+'+$)#)%%*++%&&!!($$+)**()"%#('('$++$!*!"$%*$*+$)+)$++"$%*"*'%(#$)))'+*!%*#!#(++#!)%++(!+%"+#$#$''!!'%)(&&"$&$%&'($)$(#+!+$"&#%'++)%'"#**)#'(!*+!%)%$))!+&!#*!"&$"+$#*&+!+*"'($"'!*")$$'!')%!+%+))!"##&)$####)!!%!)!($!%&!+&""&++'#"!$"$(+%#$&$&!&$
@r8309
ACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCG
+
H:23<3&/:?4E2<D<*9@0,'/>'G#=8*4<<9/+$'/?E(+FB?3+3H3":+F@F!*+?9"!21-'9,$<#!25/$+DC=(17;3"';&7B6B/94H$C(>
@r8310
NTNANCTGNCGACTGCTGAANAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGANNCNCTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTC
+
&$$)"#"&*'+'#)++++*%+"%%&*#&!'"""*''")+&*&*!)%!')!*')!"*'++(%(')!*')&+(&$&$&&%")&&#%"")!%)**!%%(')&"""%*'&)!""%$"&%''!+""#!&)&)"**#*%+!"+#&+!")(((*%*$%$$!&#$%(
@r8311
CCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCC
+
8B"?HB?5(+EB44E7@D1,'A>H<%*1&&"!0E:''B?2;D2+@99;6!$/<$%/5,=?(,D*0&&&4*.#,A&8>H<!$#F;C7?'7F?-6(C%B
@r8312
CGCGCCGGTTCAGCAGACTGAAATCCAGCNGATGCATATCCGGATCGCTGAAAAACAGGCT
+
#(++""%&')%)'"%"$+"'#""$'+!&!*'"#(%*'#$&(+#$*%)")($$*$*'*$!'&
@r8313
NTTCNGAGNANCCNNNNNGNNCTGATNGNTCNGNNGGAAGATTNNANAGTTCCTCNCTCNTACCANAGANCNTGATCNCNAAATTCANGGNANNNNNANTTNCGNNNNTNNNGCATAANNGANNNNNGNCACNNTCA
+
!"$#$##"#"!""#$#"!"#$"$$!"!$"##$$$$#"""!$"#!""$"!#$"!!$"!!$!"#$##!#!$#$"!"""$"#$###!$#$"##!$#"!#!$"$#"$!$"!#$#"#!$"$!!!#!#!$##!!$"!!!#$!$
@r8314
TCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCANCCGCTGGCNCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGNACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCCCGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGT
+
."38,G";@.72(&%1*./E#0/.=B">:-6>F'C/01,1/9(;3<2*%>F.F1-=945.(+-E?DHCG#28-&E3.4>5108*?!G/=-;@H-'7-G5/#574?;A<'B1&>"<$1D50A)!D*=CA.@"&+);*:-40/&E#+)<E,D//F8*,8-40CHA:+)C*0411?8+75E(>9.+"2$+%%0'*3:$D2C.H";6/6'3&6F%;-,):F=EE(=H=H-3B;FD%<A>=F*>.F/$E%B=)D9;.6>C+/A%!.#&.<H0G!&5((?>C)2.FA1AH*!4>&.B!--6ED)91?
@r8315
NAGGTNTATTANGTGCTGNTCTTTCCCTTTATTTTTGCTGCGNTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCCATGCGCCGACCAGAACACCTTGCCGATC
+
!"%*)#''*'*!%&'&'"!+'#")+'!'&%%##%%#+)+%$"+%"%'$'&)"!+$#)!(!'!*#&$+*%'**)%##$)$#!'$!*#$+*#$$)((*'%!#$%&'#)!"+#"(#()*"($#"+!##%(()$"$)'!#'$'#*"#"#"))$)**)#'*!$"")$''%+'()*#"%#('&$#)#(*
@r8316
TGGTGGTNTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATNGGCACATTGGCAGCTAATCCGGAATCGCACTTA
+
05-<F&?-%%5>,;('/4%->%)@H-?)H9<B$"&@8+B:B+,@3*/!&-#;9/"D99*;!6A#9:$'<!$<B"5,1F.=
@r8317
CNNTCAAAAAGCCNGAGTNGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGNAACTGATAACGGACGTCAGAAAA
+
##%(+!%+$"'*$!''%+$$%)+!#((&'+*'#!#+(#*%$"#)%)(!$'%()(!()(&*'%&')++(&+!!")$+!%"')#($*&!'"'(%)*)"!!$")%%+#
@r8318
GGATTTATTTTATCTGAACTTGCTACGGCGGGTTTTGTTTTATGGAGNTGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGGANAGCCATTCAACAGAGTTATCGA
+
,3+;&?2=0-/7@"+0B1427.8)&"48%!#B@%0"G*$EGD)+9283&-.3.--#740,0/>@="=7/#/A*;DF41#A'G)1HB@/3H6>4GH@<;@0.,)5DF0DC8
@r8319
TTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATC
+
1"1A:'70,5<.+4C):3(97.)E6(0.>;'>)G:;:.&/3A1,2?87>H"F5H=(!(3;E;<50:$3@?>;?"F0"3*9.'9F$2F?#9'$$6658C':F$82:D:0D@887;3G154<1=69=+=!'E+#('6;D=&.C*9+#?@(E-</=,6+=($>5<$#$"%8(4C;%2&#)9CH'*969*H4F7E&1D1A(?AA!2-096='B!)E
@r8320
ANGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAACCGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCANGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGG
+
*)*$*++#'+)$)&"&))'(#&!%&!&+&'$++*)#&+'(&##)*+$""$$%*%+%##'%+''&%$++%**#!)$+'+%!+)+$)'&""(#"))!"%!&"$$''$#)&&$&&#'&*"(#+$(*&#"&($(()"#$))%)+'*##$$
@r8321
CATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGC
+
4(E)'FEH4E'-0798C#'()D7&D9.16<87%CC)7F;$H+3=)G"94/9F8*.
@r8322
TGCGTAAAACCTATGGGTGGAATAAACCAATGNACAGAAT
+
E:>$29?2C5GF3,C*3(2#1>74(C7@#'%F-G12B"6=
@r8323
GAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTTTTGAGCGCAAGAATCAGNGCACANGGTACAGCAAGCCTGGCGAACGCGGNAGTTAACATGCAGTGGACGCCAGAAAATTAAGCGAAAATCGATTCCTCTTAGCTANTTACTTAGATATTNGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACT
+
<HAD78;F=?*0%!#+H:G0#=%+/#$-A"2@F:?4+CH-=4<*!E68<;@0,9>*$72?489=4"C*%@1:AH$FF.*(22CB;94>2BHA<<4H;%+$:E:$7:$+$>;E00)G8'-!0'BB8,5!5GG!>'%-)$0&A$>/9&;F<F771H?34F(=8(@B'@,??A$!=()H3BF#/5A?E$@GA.H@3C;<39#(>D1A4>;.)2+21C5!59D-!F=/(=0%(#9G-5>8-'G0?&/>G?D6#6A+'
@r8324
ATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATG
+
AF$;<C+*7)(?E,1C7-?.+.4G9'EH:-21$4-5./7)*F7;DGG92E7"8%75E6*>4F),0>.4G7%<%$(C29,E$35=5$=*17?6A$!#%0:'E'./8.4=@9#"%<3-F)(B@6-/),**,*8;7:?F8&":(5/6?,#'*+?0C4
@r8325
CTGATTCCNNTTTGAGCAAGGCTATGTGCCAGCTCGATACTCGTTCTTAACTCAACAGANGATGCTTT
+
)(##'$*&)+(()'*&+((&"$!&"#$+)(++%++!%$$#)*+"!%%!#'*!$&*"&#(#$"#**+**
@r8326
ACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCNGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCNATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCNGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAG
+
8G+,#*E")'=6)2+=,*F,#6$E$86><2&%592',.0:F-:?H,/E,*>6!7A1DGH*A-#>!+D)080<:&FE)5?>:9EAF)D5&G6%<9#9=0012:$B7(70GD7+:36/%$&C:D-155;D6F@$)55";/,1$F@C68)'D&5>7'/&+*,:H!+5"@2,,B;9@0(/$@".E5CC7FB26."52-4B-8-CDE(4'@'!>*2G4)F5&.8C!1=FFFC5<3.2+(8!.E%$A)D@1"E'B@FE/B796!$A!%42=C.D>3<58'$'-0E89),;"G-C02'HFFE:A%*&B47H($1G160""$9A
@r8327
GNACTAGNNNCGCTCCACAGCNNGCTGCCGGACNGGGGGATGTTATTCTCCTCACTGCGGCCCATNTCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTNTTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGA
+
$%&*)!%)&&''&*"*)*""$'&**$$))'(&$"%##&%++'*!)"*%()%&%!((+%+)&($')#)'*!#$'"+$"!+$!)+&%!+!(#!+&(#*(+''+%")$)++''+%#""!##)!*#)$%%#%")()')'((%'(!&+#**$#
@r8328
CNAAAAATAAAATANCNTATTTTGCNGAAAATGATGCCGCCAGCCNGACTGAACTGAGTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAAT
+
'"'''(*#(&)$**"#"(++"(&*##$!#)(*#)%(&)&'!"#!#!)*(!'(#$&'*!('%$"#"%&((%*&#&%&#+#!%)!))&(&##)%"*((*+"*!(**"%&&)$*
@r8329
GATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGT
+
:')%60/6E+'%$F3BE".".F$5/#;):"FC3<<+A53DC
@r8330
GNTATGNNCACGGTGTTACGGACNGTTACANACTGTTCCGGGATGCTTATCATC
+
'!((%*&++$+$"!#$&+*%"+#$%!##$*($")&%#+$"#*&%$+&%%("$$$
@r8331
CCTTCATCTACATAAACACCTTCGTGANGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAA
+
"+(%&*$+&&(*(&*'%(!'#'"!''!'#(!%)%&&$"+"")((&(&%&#)%*('%#%'"#(%'($)%+)#
@r8332
NNGTTCNNCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCGGTAACACACTC
+
(%))"$(%&)$+###$&'""")&*+(&)")'!%"#%!)')$$(%()%$'"&+%++(*#%##'#+
@r8333
AAGNTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCNCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAG
+
,9F<>12(8D2'E@*G033?D6<6C.">,B.'9*?)G>29?<4))%HE#F43=-,$?C,>@C?=!C5BC+398A
@r8334
GGGTCNGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTNACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCNATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCA
+
@3B5.B22@"/?!;18H,*7)B07GC@=96A.>4F=F*E9498F3?$D7;'D?$##0;C+689F99B<A?:H-'+'EF)*!7;=.,5H908;&2H+%61>E3C%9%,$3;G7F4/#7.*%8-'<>%):E8C8@6420"=G),1#)<#<9<2287$#1HF46*.#.BAA?%@-"+E@$F(8<?1+E7($,;<-$<2+!1%H4#?1-1"=+#(&5EB.21;"/"?89#3@EE5B(?@B*&1+""!69)E*6D9FC<;
@r8335
NCNTACGGCCANTGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGC
+
&(&+#(%&")&%#)($*%&&+(%'!!%#$#'*)+#++'(&!!+'&"%$(
@r8336
CCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGANGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTT
+
1H:2CGB8#>9>6HA'%+?--1(!5='.3,A$C7%E%6!6&8$D+-7C>%1:B4CF;C,#2=&/=74,:6A%;'1F!6>33&CA83*F9G8CD++=E%*3%9?@H>G:4,2B8C;6E8
@r8337
GGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCC
+
9?C5!*4,&GEF'50/C)<9G#$$-0BBC1<'*1(B/0;@5BFDG,8FD6#$$H+?-E;-
@r8338
NTNCNAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGAAGCAATCAGGATTGCAATCNTGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGNAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTA
+
%&!)$+)*$(&#!("!(!'))#)*#'&&*%*$####"#$!$"&++"*$"**!+%%$""&**%*$)!(!%%!!&()+""##$&)%!'')'&&!%!(#%%(&(+'"$"'*#%''&&*!*'*)%+'!"%!+'$%'"&)+("")!(')+*)#))("!$"#(!*$%*""*!!'!'+#*+(""+#"**")!#(($
@r8339
TCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTTGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCA
+
0@/'F+9%9EH=)(+7C?:+=:3&9(=*38.>:?67G?=<AB2-)E%9*F$B@64$+HH+@-,:F?GH?@DG?E'G;%</G(%@5='(G!>8&.FA9E&C#025='6&$9
@r8340
NTNATCCATGGACGAAAGAAATTTACGCCTTTCCTGATAA
+
(#!)'"$+$*(%#")$!("'&%%*)+("'!#*)("%*$'!
@r8341
ACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTTCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAA
+
7DF(FA#15E//.HF%.F0&35*"3('&81=%6-C.(8?;(3+0)7!;5//4*$DA:''97$2A5:DF:902/@D#>*:)BA<1=;?/)-G8!!=($%?6FA3$@30#><'!3&E1('#,2&:+
@r8342
CGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCNCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATANGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCATGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAG
+
G-#1/(@0CEG'1.&6"5!%#*.@!.;.+69A6(>8-34C?H2&/8H"=5")0/=&4>8&FG/D5#&%;6",C5$=,936C$"+/F3FF57*/.#2>8GF+%#!381B;:)"4=<89C8D?1;1H>3"5'"<B&CD.@38!?4>HD$4,.!+2+3!H(;<07<#*F.-=@C)+%<2A<+)G@F()*<?!?)2:H/A<?2&EH#835&%AEHD4E):@727?+C<>GE.99#@%:7@#AB3E.9*D@&&.8.,/D+4-1$#=<9@DE4E674<82/+9-6&8-36)38-*B=#4!AA?,:';)4F8+4587EF$;*0C6!&'9F?C9)&
@r8343
AACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGNCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCT
+
$9**)E1@<$/F,?$?;&HG,,&-EC9"<<8*5F?;99%15.A(4G9!%/(=;$G$DF<HA'*$14A-3D0/&>;?<B?78)H;7
@r8344
CGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATNCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGA
+
2+2D5G4(==!?F:>),G%(>>&AG&5+7(D-7>2B2A=#H::?'46?H3<D!?0A/)C;5<7+*A<;E*76;%@*B=4:@5;'29,;747D2B*/@<60/ED1;/AH)4+$"8)-0#C>B(.?3/A7:<+6>?DA!1584F8H87C6G$;8#EA<D0+<608)*%<F6.&)0*3@--#*!B!?56;A;5*%'((*<%%:1;;86?*8CE*B>!#2E;+"68AC9E1)4B5>2+"";8'EF&<8.584%<3$::C>!C<A'A-*A4>?0G?=;A$H037&%
@r8345
CTATTAATGCATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATAACGCATTTTTCACCAT
+
,A-7ED!7->13728A#&35+"?47D/F)@('H0;97+09-/4B#1G#>G'>4!2-01&97:B$9F;27!0%%:GF$@+E&
@r8346
TCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGA
+
8<8-&$(&1BF=$F9@6$-<4+C;%2*A2A"2H!<4)(DD?,;;:D,=&+*/4>9>>,E3CG2>*10;G<+/@(-D8"&@?='2'@$=,)$'464#&C<A&:A+9)>&
@r8347
TGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTC
+
58-.%B%-GA<?*=1B);49>6!)&(H%C:E*F@2495=?E38+&#59?=E.,(HG6+.-H=*$,FH%D(/1G73($+"8><'-/*)/;;8)F7)%37=753@<
@r8348
GCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGC
+
A@*9>!;19:G12C0CE"/=#*$=.CD&'';-0>(D8A?D0G(&B3@B&78;>0(=-!%1A!H'&1+F6#'C988<$"?5-2E3F5D/",B)<%
@r8349
ATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTAGGTGACGTTGGGGGGACTGAACCTCCACGC
+
2+'E,",;&H7HH&026FD"36=B>0+?7225=?59'E8G:@/">9&*+7+6#$G.(F<A'(ECC.F/8&9:;91).*CB<#F>*?8656&5$'21(G5='$!DB*<"=$+$$<4<;9*-;6HA$$,9=/8+"4%AA&23
@r8350
TTCCTNTTGNNNNNNNTNCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTNTTTCGTCCCCGTCAGGCTGACATCACGGTTNAGNTGTTCACCCAG
+
!&)*"!!)##%#"%!#'"+*("("$"##&(&'$#'*")#)$%!**&)'*')((+#%+)+%%&$'+"&$*"&(!!%)!!'$$#*+)**#!'*$##&!$#"
@r8351
ACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTT
+
;=B:=:BD,8A&H'8/)<F69"=G#&A;:/H>#.2&/.)B,
@r8352
GCCGCATCGACCTTCGTGTNAAAACGGNGGCTGAAGCCATCCGGGCANTGGCCACACAGCTCCCGG
+
(D7F<*=*(12DH3F5?!")H)@6D%4H8<$>7E+F=7?71H4&CB7(F./3-"B8#7&0,*D!35
@r8353
TGAGTATCTGCATATGATGTCTGACGCTGGCATTCNCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGATTTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATNATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTNCATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATA
+
B&88=@=-://?:%7<?C!,12F3#<-7--H@HD,)(5>=0FG@;:E4&4B39>%E@F<C<DA;)D$)8=G"2-3713H="&=6<<%8CG:$*>3E,:">7!9F?1%-8#08*#E,"(-GC;2%;,5.@+7*=?C<G=<;+$,>C"(G49*$+'3,%H9G8H')!H4&/B@%#13,D132H@77"'<-&4?@,$-$3=&.++37%('""=+47-G/#A5G4%C&CH.CC#")3@7)=)0/G6
@r8354
ACTNNTNAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATANACACCTTCGT
+
'')%""!+"%''!&!*))!%&)+$+!*)'&*"($"%'#$(##$*)$*+$%($%#'!''#)'(%*"(%%*(*%
@r8355
NNNAGCCGGGGGCTGACTGGCCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATCGCGATAATCCGTTGGCGCTGAATAACGTCGTGTCAGAGCAGAAAAAGACCTGGGCGGGTGAAGACCAGCTTCGCGGGAACTNGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGAC
+
!"$*+$("%$)&+($+*&+&+#"+')++*$)%$'"%($)$)()%!&!'##+)*+#$!!!%*+"(*!*&"!&"*'#)+##+"+*$$%'$!(*"#"#*'%&&"!**((*)&!)'$")*!)%!#+'*%*#(&#*"('+*(+*'!'*(#&!&)"")&!+#("*!+$)+''(&%')""(('!*#)(+#"+$'(#"*)#$%)(('!&*(""!(*%&'(&($*((((+)!)#$&'!+&("+(*+
@r8356
ACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTGACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACT
+
)4G)B8FA@&@"06+0H"(96./(=0>=-(":5<A8*).1HA;$5%@@15@-;&F0B8&2C+!E=AB(&060.70H':)&3?&;9:$=.-./$.'@'/23F#D:B8C$G3+86BF9#;A'?A+2F*+F=4B0DGD9;'9++"+*";0+"@;!#;*246D=E8##3;C(48>;!%@&8CH->#1:E3#7BAE/@C4&D=5?F">B-B2?,A&2320F2?+>#?!>)?G)58-A.8!54#@'6
@r8357
CGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAAC
+
///*+<F?!3$@$#!!!)C!*>4215,?)-7?AC&1F8&?%>'!+%"!:?-'$=%(4!3>H$,$!D%:&CB"4?>G#3#;"F$2:F;B@8'6+D
@r8358
AAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTGAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCNCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGC
+
8(>,F!=7=4!%!1B8%-8;7F73?8099(/,A:H&4*GDH#++*(412%<%B<=%=#9H<G%?5F@)'98H?0F1$=8=2#AH*"!)?*$<<C'#>F%B#.<6/FC*FG@H5=.@46B$,?G7$#(;.43G?D*:.E0$G><')4:3A(9C<F.!9""F%!1G4C=F1@'>55*/$;.7BH+9C1$D(A+=-)7%E@AH+/;8"4H<3C8F(!F;F0"'5F@0B*5>/.'=A%:'>&=3HG,;9+#>F4F%0G$:%@!D:FH'
@r8359
CTANTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATT
+
'HG3AAA:1A$,H81;C62%2#-EBE&G6F0;#1'<<'7')3A<B#?F*>7ED.*B4'E152);5<2';0!82!E8)&5A2/?/?#!@;33.&<;'BE/E2;"6*@>%FCF9%DC4BC,@4.7+@11/G$80F7H2$4$%)/37&0E>FCB"13$0%7A..1<H('D';6%@')4+B)75#A$66%<89(3=2<HE)&$@#>9$>C(=-+=;8A3%-*"3GE!#-2%'.(E*<GA4(/&%#+$*,HC:+<'D7=#+F0=5--;E2GC56*FH74&42D"4/#16%,'2:=F+((C+=,B196.'%3(C@?&#'8*#19C'#/CDC??4<1#E0'=%>.4&4;CFA
@r8360
AGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCNGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCA
+
1<<$1"*#5C$)3*"+$%E'+!B=A6)!;D)&G'09&=,.D.&:!<C=H(2>A*;$:-D'0D4-C(6BD<E1@H87,*F3?"<>&(-4H:962B).5;'D.
@r8361
CGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATATGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCA
+
%,*+&1C-GCF'6'CE/<2;C594D.A7?2%+??3:CB*3-$;D6D'=&6(8?DE>2<DC'F=798DG%#=:2!G5!DB=8C4"A&$2F!+H!D0%"<E-FB."9C(
@r8362
CAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATANGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATNCTCTTCCTG
+
,B*+H!:7*3.'C1(!H35<34"1B9?'*>EH,@=1%?E5#&EAD/;!1)>&E'*G53*"1@,B'=40$73%<;6B3F;/6<.!59;E>0F59A'G(>,/=-;E:C#?E954&2!7-98).:4>+
@r8363
CAAACTGAGCCAGTCTCTGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGC
+
.G4,(%"F.8>:5:/3E'-D>GB8&.47)E#B7H9:3#+3><*9'5!<B2;C+7A+:@->:H%#A/4FC5<9?=B)4.F3'B@:
@r8364
TCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCC
+
/EGG**5B<54A>:/<,5:>;7;=?79G3::>')<3+?0AF:>1#E!7-A)&&*);
@r8365
AATACTGCTAATTTTTAGATGGNAAACGTATGTAATAGAGAGTAACTTNAAAG
+
2ABF*H&B"4<C,6BB"-#.C;.11C="55.9'43D**+&?.',@1*#H$19'
@r8366
NTCTTCTGCACGTTTTGCCGAATTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTG
+
$5&.%594:;?D/"F*=F27=<(6%#.3%9E/6#C5&>#/:8:?;"A'-A0*F>2=1G<
@r8367
TGATGATAAAGACGGGAAAATGCNCGCCATCGTCAACGACGTTCTC
+
1#;#%#-2-&:-,4,1F"70<HA51F92)"-BC6!/9#(H,.BF+3
@r8368
TTTTTAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTNACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTAC
+
"$&#"+!$%))&$$+#'%+')(+!&"&!"+&$+%*+*$$$&+!$"'*&'*%+&#!&!!'$))&+*(&%()%*%(&&)*(!%)(+*($%++!&#$((!(&)%#")!!)#
@r8369
TAATTCTGGCCTGCGGANTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGAT
+
)!+%"*"#)+(%&)&$!++%++)#&&%'*'""+&#%)&'$"%%!%'!%$")!*$!%)!'+$$""!"#$$!*"&&)+#')')&)'"!*)$%()!)$$'&%''%(&$(&!'$+
@r8370
ACANTNNNAAAAAAAGCGAAAACNCGCGAGGTCGCCGCCCGTCACTGCA
+
"$)!&#*%+!'%#&#+%'+'#"%"')+)%##*%)&#*!#*#)$"('"&'
@r8371
ACGACGACGAGAGGAGCAGAAACAGAAAGATAAACNTAAGATTCGAAAACTC
+
F076<"9D>G(A'D=?%<@!9$&>1<A%F0G44B763D11&@#F-&1'>84+
@r8372
GAACCTTTACCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAA
+
4!(#"!17@1:*;-**9:@#6";9?"@14?+7/G;B6>;1#7$H/&H":@1
@r8373
CTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGNCGTCGCTGGC
+
BAF<;"GF.%E!&>=&-$=?A$%63E>,@C97$8C(20&?>0!6G?1.G-5;79;671E1&-G+'B/:'FC26FAEH2&8E>%7BHC:7F:>;3BF8/8?8+?<1<@1@>E+/$7=FDG#H7'6C%5E$CFE"H?2#(+'E?'?(@%<6*%.&#D<:?9#/%8'#D)0HA?$<5#G
@r8374
NCATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAG
+
41E.)">A3,17!&%AE0-9G1,1>&"9,*.$/-,7/4;?0F+"705:-+,CA/F
@r8375
CAGNGNANCNTGGCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGAGGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAAT
+
!%#!*#'#*$!$+#*"#"!*!+#!&&&)"&#%+*"'$+(#*+'"%%%!++$(!(%&!(+#(%'+'$"+&()+(#"#$"&!"''$'(&+++'++*())$*)""$%)"*%($*$!!'#'*%()+"$%!$!)!&*&'*%'#"%!"&'!!$)%)%)''*
@r8376
CGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAANT
+
3+27D3:)'$FE2!!>:+H3=?B;31(A-473((%"*9>98*3D>4578.GHC8)C9)88G*#8C:'2(8<7=<=50(,"C&0D@>!EG<5/+,"%9%6%
@r8377
AACGAGNCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACTACATTCGGCAGATATTCCGCCGTATACG
+
39"A1??;6#09EE)>)"(#9,#H*&F)#473!0%@G0%<;=.60@)!%?#>'/@D*$><A=DB=8C=1%4;))&,AB>F#D<4;8!+F.F*<+&47=<+-!.>1;38":)&E&=9H
@r8378
GGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGT
+
C744"*#),EC=<5>7"H4C;E@"G-@A$C*0?!'8F,EC)>6=C<5=.7(346HB7$53GED=)CC'@-""BE703D,-+A.(9
@r8379
TCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTAT
+
9"D9B&4">$",@6@!5-0%"A8&C,=HCHCD?&(*?"90F=AG$,3F@A85'G(?%DA(8A7C=5%@3=C#=@"30'9,"02=F26D.0.<0$1/=(E
@r8380
AATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGNTGTCATGCCGTCCGGCCCCAGAANGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAA
+
?-<8))):%F!-#*"=67/5,;E,H;07/;1?6';@=('>)BB+AA)5D#17DBB-E*-GC%3.*BF(*5/5.,8-<-:1<56HF11=<*.-D6*$8;?46,"@;&(A=56*1C@0"2$@*"A?3GGD%)1C)*G'1FH+=0-'F400.HH0:0*E
@r8381
TTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGNCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCG
+
)9GG%,F8F@2&A67=-CG:F4"E!://@#A<=40CB,.::7>A5$C6$=#$78/F.=(F98<<.CA8D$!E++',9@F9?&D?(@87!:'HG!-H.H:A24)E4HG2A!@8C'"AG@'=
@r8382
TCATCACTTTTAATTGATGTATANGCTCTCTTTTCTGACGTTACTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTCCTCAAGAGCGATGT
+
#>13C/@8A+.C?9&/D)",!D--/&661,-HB70&;"D$"=!.B(./7=(81//)G%;H8&?24G;)7"!(7"9&!?B#;.0FC5,!?2B)<4A/,70;@BDCG7+*F39&
@r8383
CGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCCAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGANGCT
+
(:.F!AGE*%BH#-(EF?3+H.F:'AF7H/.+#$6@'=>85'AED72'2.1)@FA<#+B./B:A&@($GG2.HE5/03;9:*2'=E<0!697A/E)(3A5/87AF)/28>>9)$A)B1G5FF5<G0FG=F27@:*A0F-=8CC50EG?B0(*.G;7?8A2:%3?&@?44-"#E$0#HB.88-'E%6"?DE+)%3,44)C
@r8384
NGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACNTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTNCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTG
+
%,@/H$H/0+@-11'E-8%0E0;$EBA9F)&:'8"27G=54%#G9$GE77B#@"3(D9;()=*6+>A2260'8;%5@.2@F0?#"$!6&/A;9:191)4<;C;)B<@0$3A$?@DF+"3@"4D+-.%2B@%:6%.91:.%4H$2-;B2.G#
@r8385
GNTTTATCTCTGCGAGCATAATGCCNGCGTCATCCGCCAGCAGGAGCTGGACTTT
+
("6/A-;1<$F-&#%/D>7HA,!F$FC$))8+20)7@:6/=6G%A+)$77/5$?)
@r8386
TTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTC
+
-0<)C9392B?"#F0D+)(B:?7%1#>B6$"F;5#"3;/&94"!?3G
@r8387
TTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATCCATTTCTAAATCGCC
+
526=E?!2$%;1&66&%3&++*;/@*220B6.?@'F;1<(-=7.:#/=DC9"(<&47-GD!4-$<*5)$,/AB@87<2+?*.!H:&:5@H,??5=$>81'FE0256>C(2>!D"2FB>(<*+HG@85=+'@70@A#B=)14H=0D@%B5/'-8DG,#08(0$=017>034,0%7@E4.0%H;.H%#?6HG16D0=BF55.)9G&(>+=/:&%-G1!E1"0"+E5!>'E%:(H:F.6:B>-D!01DH<3(G:C#-F8,
@r8388
GNCNNNGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGG
+
%"'(##'(+&""('&'("*")#%'*+!(*!&'')(#"%$((!*$++$$$+'%%$*)!#'$"
@r8389
TGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGG
+
*H$A<9F#!*;%;1@B'90;F@+718EG(1>G5)5+=!C/7E,:,'H-CFD731AB?.BE059<#!:"'!'
@r8390
GNGAATACTGGCAATTTCACCTGCGATTCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCACTCTTCAGTTCCTGTGCGTCGGCCTGCNCACGCGTAAGTCTATGGCGTTCGT
+
(*=F/E8>A""#AH/&+?>3/61,>&A)?&*'!8,9$4&HC*<5G-B&F&2A7;$FD,"@B0:&<8BH@*,"35;?H5D96'"902046B3.A-<?1B?-%-$*C$E/H!B9&<6;;"1C>C%<9F%#HF2;"547"
@r8391
GNCTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGA
+
'!+"(*%!%")('&+&'"+%!+!!+)$"!*#+(('#&()#+!'(&*&$!#%"&%")""')(%+
@r8392
CAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCNCA
+
&+#&)&$+##(#)%(*%$&%$'!"&!#('+#""**'#)!&"!!(!*+!!#)"%%$((%$+#!'%$+#$%+#')"(!(%$%
@r8393
CATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACA
+
9<=&AC<8.&;AAG(;<+!69F1&$0.8,A()HD?<4#5*..A8!$F?0<*EB25E,;;B"$7%/))-*C1E-)+@EB5:=
@r8394
AAATGGAGAGTGTTATGACTAAAAAACCATGGGAAAGAAGACTGAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTG
+
?(E6>0:,?39B.@+259G2"B/E@8<?E?H-FE22;!(C8A:7B$/.A9>*2HD06H>B.#@'B77>6>7':?&?1:>(8"6H&8!#DC$G#C$@$:.B1B;A*%D80+
@r8395
AGCGACGCACACACTCCCTCTGGCGTCNCCGGGCATGGCGCGCATCTGCCTTTACGGGGNTTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGG
+
9E%-+#@F*,0986+CG1')0?F2E4<>,@AB7H$.H'1GG2H116;:D&'**-A<B+?)C8#++%=:!=G@<*A'2/F.*'9;;'A!2"#,(?AG.=&'$!(ED1%3+)&0>>B%(>31?FEA+5F46#,:,.6134G%0!2<11&F'+3A+A*>59F,G29$=D5#:A11<=(:,&=C;!#&#F*:2<'"#+%>/EA9(<*+2GG47?)7!1?E(DC+'
@r8396
ACAGACCAGCTGCAGAANAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAAGCCAGCAGGTGAG
+
)F$(7$;F<A<-#.?'+7>4,-!<2*1G3C7*$>!1?(&(*&'ED%9@F%5+-8=07'67@=*D:"92<51##4D2H-CB%:HD0#&<?3,$:C$>"C&'=4&/)=-:!">6*62+%11AH4!'
@r8397
NNCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTG
+
$46!3D(2+1+/4@22&5C0'#'?8%$9(E7"!4E%:%=&@
@r8398
NGAAACGCCGTTCCCGGCAGCACAAATGACACAGTTACCGGGCAACGAGT
+
%?+>8')+907<ED+.5=34:<@H6:-@DEDE)+!,C;31(,2,(88H*(
@r8399
CGGCAGATTTCTGCCCCTNCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATNCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCG
+
+#%%$*'!*'!&#'('*!'("*!"&#$*'%&'&$%!&$#((!)(*!"&#)''!))#)$**#$)%%*%&+()&&"+#'!)"(*&+!('$"++#%!%!"+((%$&)'%$(*)+&(&#+"'''!'$%$*+!&$*'*+$(!%&$)+(+$++"))#*+#'(+!&()()'#(*'!&"$#+&%"%(%%'+"*$!!!%"#!$&*!&)'$!%&#*'
@r8400
NTCTCTGCAATGTGCGAGANATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATACAGATGATT
+
*$!+"#*++'%+#'&$!!!!"**'))$!)"%!((#'%"!%("+"#%"$'%+*&"#&"*&!+)$''*)#&%)+#+((&)+'$$!"!&))"')$%*#**"+*&!
@r8401
GGCCTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGA
+
+<AH8DAF'C9>F2?<B:87?4F%'D?7HF(C%$%C48F%.B">A&9<;E.6:G'GH%3%&"/6-++7%8@$!!B*!,+CF04<35(8(A825
@r8402
ACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATNTCAAGTTTATCTTTCTG
+
80'C$G<#(/-*B!A;)$'5-/FC(+0-25</<H5@%$%6:(&#A<0D53&)*:=B2>6*<+&+=2A,83(6"!)'&
@r8403
ACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACG
+
A"78@+*%7D,,F?"CDE5:3DHH/C@@E%?5C:&0!8A!@+4'H$:+>E)EH+?!B@$-C#C')2A1A=.<,=8@5H2=>!D.FG8:=+//&,-,=@%>5(5:,G1"#+-E5>B=/$$#C."/?1%,%3F2;2"E5*.$.D=9D)"D6/+?@=99&+$;:94+FD#>7&C4+(B5D4@$%7!">!/;93!*%@
@r8404
ATNTTCAANGCAGCGAGNGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGNTGCTTCCGCTGACGTTTCGCGGAAGTANGCGTACTGNCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGGGCGGTGATTTATGATGGCGCGTCGAACGAGCCGGTACAGGTGTT
+
)%#'(!'*#(*+!(!+#*##&##&'$#%+'(*$#%*%!%!%+))(#(*")"$*&#"%#*(%#&)'%*+)')!$*%&&('%!#'#*$)")'"'**#(+()#*$$%$#"(+''*)'''(#'!"#$("%'!""(%$$#%(()"#%)+%%"*'++++%!"))!%'&'(+&+'($+*('*+)+&#&"*&%$"$%!*(+)*%"$+&&))(&%"&(+(("+'$#'"$**)+&&(%&"#'#)(&))!$(++"(%#+!"%
@r8405
CTGCTCCTTTNATTTCGAACTTAGCTTTGATTTCTGCGATCTTCACCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCNTGGTTAATTC
+
%'&$"#)('('(#))(%%('(%++#')$$!*(#&+)"%++$"'"(#!+!$&*%)*+'''&'%$(#$)(&"$#%%(((+$(%)#(#"'#)"!!(#"!!!**#++!#++)$'*'#'++#+)(%+%#*$!'#%$'
@r8406
CTATCCGTANGTCTACGACTATNGATAAAAATCAATGGTGTGGACAATTCAAGCGNTGC
+
8:(D.8419)%38?7.1<$5;G<)54*'+<0D6!(5C46<1E+4#&03B/GFDB5F%=2
@r8407
GACTGGAATGATGGAAATGGTCGGGAAGGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAG
+
:63:<@B9/3(/7<3)'G9??5@.(A5GG92'-5'!#F1D%:79)(%/B6E:C1-)H3*D,!87(43-6(H+)/1%""@&B5C+6,'*097=,$C:)<3$
@r8408
CCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGC
+
9,?A&<($(.E0(?C*E)+H//#>,.0<09?&.,2.&:C(
@r8409
TGNGNNANATGNCGNTGNNCCGNAATTGNATNGNCNNCGNGGNTGNNGNTTNNGGAGNGNCNNANCAANGAGAANNCNTANAAANTNTTNTNANCN
+
"$!"#"$!#"#$$$$$#!""$"$$!$$!$#!#$!$!#"$$!##"$!##"$###$$"$"$#$$!$""#$"$$$$"#!"""$$"##"""$$#!!#$##
@r8410
GACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCATTAATACGCTTGTCACCCAGGAACGTCGGAGAGC
+
**C:"G'(FFCE,C)48'/%>%,24F,E+A9>$C/F:E8;E$%=(-%;4@37)%,"!(!?;/A4D6F0FC<!'(D2=#H!G9/<H%8,DC5<4:.#-(F?+4!9A0B80HH4<:
@r8411
TCACCCTCAAGNGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAG
+
7+2'13'>>'$A0C;8;H.;02%ED(;$)>63A<E>D%(10@;448BH+"&(B0&.%$:@!<2+B4D46&A*;7/0!"D;'<.DE$,+#0)39$<-
@r8412
GNTCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTNGCGCAGATCATCAACGGTGTGNTCAGCCAGTTACTNGCAACTTTCCCGGCGNGCCTGGCNAACCGTGACCAGAACGAAGTGAACGAAATCC
+
)"!##++'!(&%)&&)$+"+$)"+"&)*&)"%)'$#*&)$%'$)!'!##"#&%+!&)"'++$%'%%!'$%(&($)$+(*"")""+#*'*)$##($#"$'"%###+*++!*#%"(+)!$!%!*((!(++$%#)&%)+!&%&!'*)'("(*!"&!(!'#%(#*+$("&*'"$("*#)*+)#'+!'!'$)%+'#&%"$#++!&!!$#
@r8413
GAAGCAACANACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTANGTCACGCACACGGGCGATGATGTCAGCGCAGTCAATTGCCCCCGCCACCAT
+
")%'*&&'"$+*!!!*"*&&($'++'"*!"*"(!%)+'!)$*&)#"%%)(&)''!(*)"+"!$&")**")&#"#"&&')+&'+&!&*!")!)$'%$*(+#*(+&%%&&$
@r8414
CGTGGCAATCATGCTGCTANCGTGTGACCGCATTCAAAATGTTGTCTG
+
F-*7.7#B"1AA=E<.;#?%=:#*A;-&/%'.A@""0F/(D&A&+)1F
@r8415
GAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTNTGACCTACAAAACCAATTTTAAC
+
;;24$!"?(+,$4!$!@:/F@=F2D"H-B>'A7HF4/."3+3CC;4&+27072))6>"F+*:F;A$
@r8416
AGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATT
+
2-8!*D.>.CH>::?B($C0;,$'0!?>0G12&2F"G$H#(9</?3'@G=?)EH<<"'C@F0$/&,=%C62'8<A4*:H!+->8:&,C*087AE!-
@r8417
GTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTC
+
)<(>C-@7A=61'GB60,D>;<@!17560?$'.F?=A;$E%8+.+@H#::/4<G$+(B99;%4C9
@r8418
GAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACA
+
9B)+01H$4*-#6G",#9&:1,A1)+9!14E*9"$?FD#".72E*?5"D21>%95)*.+=
@r8419
NCGNNGTANATTNCANNACAANNNNNNNANANTNCCNNGGAGNNANNNNNNNNNCCNNACTNGTCNCNNNNGGCNNNTNTNNAGNANNGNNNNNNNGNNAGTAANACNNANNCNCCNCNTGNNNNTNNCTCNTNNNNATGGGNANNCNGNGNNGNNNCGCTCNT
+
""!!$!"#!"$!!!"!#$!"$!#"###!!"!!"!!$""!!"#""$!###!""$!!$""!"!##$"!#$##!#$#$!$$!$!#"!!$$"!#!$"!!!##!!#$$!"""#""#""!#!$!#"$$!"#$""##!#$"!!$$$$$"!"!$###!$##"""!"$$#$$$
@r8420
NTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACCCAATNGTTCCTGGCT
+
#&#$+'&((+$"%&$!(#%&&*$+"""!$+"&"(*+*$)+!&#*##()+"&'('(*+#)%$)"
@r8421
TCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATGGAGTA
+
&+*#)#"*)"%$'%#")$)#"#+'$)$(")'*%+&(!"+$++*$)$&%$$+&++#)%$)+"+'"**!$("$$+$$&$**"!+("'+$!#+'!&%'#!''&'""$!%*!'%&%)$+
@r8422
GGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGTATGGAATGGAGAGCCATTCAA
+
E>'G-F$$,.91G4(1.2"")=8,4F'!&@-=@B+8D-%=8?.5"HF<D(6?5%:)%)#'BH+74>DF:*&:5FG+0(E8(9;(=)D/D?&#;@,&A:
@r8423
NCNTCAGTTTCGTTTAGTGCATTTGATCCTTTTACNCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCT
+
'!!+'#%+&((!*&%&$%!#""*)#%&*###!#($&%"%+$$"*))'"#%))'%$'&%(%$#()+$"!!*&*)!#($()!'"'"$$)&"'(#&#'*'"+!#"
@r8424
TGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTT
+
1:<#394"&(G>@B.7#9D=F,,6<>3H6B/?!<)%3A?%=#>9)DD6"6GG%337)298C3=681*$1.,H-'&F,H?9=8@'!"B1-ABG?8D11B
@r8425
GACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCNCCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAAAACTCGTCAGAAAGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAANATCCCCTAAAACGAGGGATAAAACATCCCTCA
+
;(G4>EC-$1-B8,E'64CA(/#3"@GC9#3E4G/C*0%83?H-7$,<*$G/6@FFE1<)==D*0EF(453:D3,25A2G$&67#5C/D,5B?<.'>H=4/,$8.7D6-#:,AAD6FE=.BH=1&)G.8-?!!*/")9<D8(#$H!0097211!"G='E(HD+":$="$HE":D$C/$<+8;)3,%EBB1@;<(>4?#!<F1D=#79!?7%9<//>=$*@0(,+H1%?/1(!>"<&$>7E.H:=94;9H4::EE+3!=
@r8426
AGCCATCACCCCCACACTTTCCGTNAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGGATCCCCNCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCAGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGC
+
:9&;":+?#C#D++1E08GC*1-&5G*A3!&80-A?B7=DG138G)94<544@=E=5G.%9*##'431G=;(3D<%@2$6:H";@G0.85:,55068A&9.9&!'=1@C=++>0"FE)8E;468),75+A"$'35F*H2D?*#0&''8,"/72)".8-?'929*-;%77E/0%=?%*-!?G-->G397@",FCE&/;8
@r8427
CTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTG
+
;?F,"7?F>:-2$;6C#F..,,G>BC*%=.;$D',(:!<.7A7(&,=08;"-%/,F'DD#6886'?6
@r8428
AAANCTTACTNTGNNGGTGNAAGCTGCCGGGACCTCCCTGTGGGTTT
+
($%!'")&$'"''((&&)*$)#("$%))$&)$*&*%+#*)*'$$)!$
@r8429
GTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCANTCATCGTTTTTACATCGTCTTCGCGCTGGNTTAGCC
+
$G-F%(991-:D6+7;.>A#"*5CB2>5C/-C#+!=?%/GH0"(4D$,#(;-#/EBFC"B79B*3"-:'!);;B1H$2<<5!F"8.BAB'.&2G"3A%&,?0,@F:/E<05>;;%D
@r8430
GATTAACGNAAGTTCATCTGCTTTATGGGCAAGGCTTTTGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTC
+
E:A31*.++)$5'.:G573:0:D7D,!=">--9>4$7*,F<H703A>AAD!=-!$AB7:19#DD/7F$@9.&:"=2$8>D70E)=52>!>,+H&B4%@!E68*H3#6H/7)!1F5B!9<$E$G&'!')5#5$F$-0H02:'?6HG"-E/'E+1A0/)#79G;H6*4:?A5<AC4HE<5,CD44+F!49;!2C*H?#4*("#70?E-!1##E%"A=0,A0$&-G+6;F<7$C6B002=D*2$A#C,)F<90<#!,>/'*3+8$)
@r8431
ANAGNTNGCTTGGCTTCGACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTNCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACANTCCTTTCCCGATTAANAAATCTGTCAGATCGGATGTGGTCGGCNCGAAAACAGTTCTGGCAAAACCAATGGTGTCNCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACAGAAGCTTTAGAGCGATTT
+
%"'%)&"+'#'++#)$#!*'&"&'#!+&(**('*!*)"""'%$'(#!)%"++&!+)$+&&'&''#(!+&"!+%&#&%*')+#!*(!$#&%%)"*(""!#(%!&&'++"'$$&$+$'!+%+('$('%$$*!%$!"%%&*"$+#(("!!)"%$)))&&"$++!"(*!%!#"+""!#!&!$&'#*"*)#('($#+$$$(#''+#&&#''+&*%!$+)'$+%#"$$'%#%#&&!$("%!+"#(**%&(**+($+%%+#("&+%#*'&!')!(&('#("())''*(!+#&'((')'
@r8432
CATCCCTTACACTGGTGTGTTCAGCAAATCGNTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGCTGCCGGNGCCCCCTGCATCAGACGATCCAGCGCAGTGTCAGTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGG
+
@D0#?-:0E<4'(&A"EBGD(6&!F>&<,5$=#9C9/6B0C=4#3<A(<)1=56:(4%/#<.=>G1&7>,@,2C4D?/801E-:-)C-"(B<#<@>9?DG,*AD5E!G0F!G0:;&E+5-1AF7,<>%E9E)A6>A9,A:CF?A.0?8?+A@@D
@r8433
CGATATGCAGCTCCGCCTGCCAGGTATTGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGACATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCA
+
@<%62;FB)@D?>/<G4-::"?87!$6;F$6E7/=H$6-.7,18'E)E3F5=2A<";"#G>97"A0H/9:%HFF&0@>-6A86#>-*/B/3007AH#;)!BC9=1/E@G#D!F.7@G:.B"*6.F<&7F6"&<*5E;5:3G$2&;>'-+E@)-
@r8434
CCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCG
+
)1:(EB.8,H:BBC?(A3'9B6>3#?=("A?#37FCC'B:>14::1B='"#@11H61***3'6*%7%/62B+/;?F@#9&%:4D@@35005-1%)?5$);09=D*34:/="F?0)E>=0?!!8F$/AH9
@r8435
TGTGATCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCA
+
3D(5662($?H%F:0,?@9H&9!:%.7H6$2B0CB(9-:64;B521
@r8436
CCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCANTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGACAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGNGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTNAGCTGAAAGCCAGACGTAACAGCACCACGGTGGNGGTGAACACGGTGGGCTCAGAGANTCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTTCGGTCAGTACAGTG
+
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
@r8437
GCTCTGCGGCTTTCTGNTTCAGGAATCCAAGAGCTTTTACT
+
)626#'@"7;=&(@#&5F&#(<$@!/!.'*1*<4?B)$5?C
@r8438
ATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCA
+
9.$*6EA+?4#;154/%0;F*%H<A>!B+)H$.CC>F7HE"04,:F$F=-G)%7:5+47)?
@r8439
NNCNTNGGCATTCNGNGAANNCTGNNTCCGATTANAAACGTCAAGGCAGCAATCAGGATTGCAATC
+
&"!"*"*!'"!**(*!$"'%#!$($+(&!!""%%'%%''+&$$!)")('#*%!(%++()'+(+(*$
@r8440
GCATCTGCGTCTTCTGCAGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCANAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCANTGCGCTG
+
(F<?&D=H8;)3$9!3C/(?<C+;'.32@$A*<H.;)H&.>812>HEHFG,,,.E/&$?+2!20E822/">),,2/0#.2+'EF568"D+0+A&D"-$0+:?5.6=@)(BE=E,6(4F+2.&"+*F)F51GE%55>96-)GG5?F@F!+=2.!.
@r8441
GTAGCACTGTTTCACATCGATGATTTCAGAGTATGACGACCGGA
+
'(#*+#!'!&$"&$$'&!(*'$(*'%&*!("+'#)+%!%&*+'%
@r8442
CCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAANTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCA
+
:*68/@;H(G)47?58$8',HEHGB!$A>,,+(>B9(E>,2=<#)E'9'!/8F(<3;;EB)>#@6-E/3>2"#&!5*3"'57!$!$+)4A#-6??)F.%*)-.AE%(C#E:+%35BFC43B4*C1@87E9":#(H-E
@r8443
CCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCNT
+
7$:.0)10D"@$71."G/HE-1.*!*B3/7:9;E(32/?2F&5C(<
@r8444
GCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCG
+
-.=(*9>1E-??G7+,FHEBC#)*A%:D'"$/:!$;6D??.%=,6,!.E"H46<50<AFC#-!>$0(G$C39<F)!(13:@#FC;3?0-+12<3="4HBB7+D+A1#$:BE:;:8/?F=4E7?-$1/$B0<8//B+:6#73G>#0C6C$DC=<H2'BH@);<=5;"(5,C"/+9<,/H0""79BB=?$!,!&<<53B*
@r8445
CANATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTAAT
+
A:<(#0&DA<3=#2:6*A:F3C7(9BBE&4>7G3D@@&<@>."E:;0@.
@r8446
GAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGNTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGCTTGGCAAACTTGAGTGGTNTCACTGCTGGCGTATGACNAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGAT
+
0G53*/GE$.@2F?41#)F/*A8E>F4)C?,A+(*<**#>FGAAC&:B*(*:B!HFAB/2B(=%#4G!@>!#2:.=$$3F,'?*:HE"G94;1H;?5-"!FC*BB/.:7"GE.1"./D3++E,9&?$9F00,GE'17+@'6F0F$C#AB2:$-GE43(>D41*:1:C!-6"AC>=$@@,;D87#<4/<3)?B9?1D4C(9:24D211"):./B*B5H%176*<?H@3D,,,7!$.*H4#)@C59)(G:;7=BGC=09(&*5@.2"0=,$EG?4F-%F!#=1/;GA
@r8447
CCGNNNATANTTNATCNNCGNNNNTGNTTATCTGTATGTTTTATATATGAATTTATTTTTTGCAGGGGGGCNTTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAG
+
#)#$*"*'#)'(#&'*&)##&&)"(&$+!"'$$#$"(+&'+&*())!(%'("'""#*"&+$#%#"+)%)+)$$#'!')&&#''!)(##*)&'$)!)+!!(&*)%+((#&&
@r8448
GGGAANTNNACNGNNGNANGGNCCGGGAATNNTTTNAACGATGCACACAGGGTTTACNG
+
('%)*'&#!"'!(!!#!)$''!%(%*#%%&!#()'++($()+#*%"'$()"&'#($$()
@r8449
GNTATGCGCGCACGAAAAGCATCAGNTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACTAGTTGCGCA
+
!!**%+')%"!*')#$&+(+$+#&&'))$#%&'*&&*+)#%##"%&'&*%%**#'"&))%'('%**+)+&
@r8450
TCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGC
+
-(57'(2&B#%10=.!A>%&#2+4/B<;)C$"-$-<2(5.;4G+>B:3E9%?H#'.>:53A11AB>B!@63!:!--2=6=.
@r8451
TTTGAGTCTGCTNTTGATATTTCTAAAGTCGGTTTATTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCTAATTACCTGAAGACTTTCATCTATAATTGGCATTGTATGTNTTGGTTTATTGGAGTAGATGCTTGCTTTTCTGNGCCATAGCTCTGATGTCCAAATGAAGCCATAGGCATTTTTTATTTTGGCTCTGTCAGCTG
+
@:G>.."3)D2B!G-(.;-$)D*,$H<#C1CFG2<-#%=!B.&?GGE)08%&'8C*/!@/B"@A;!8*A:-E%,D4<9!,-G"*G#<(#="<-2&8F"/55C.<6#(7DA,-%+%1G5-<H5#=//+"4.+(B831;=9*CE.13.>?3:=DC0<,+1@E!;'A'2.CH866/$<:)E4',G!5B/-&*5@<@H<.4%4/<72;&92/5=H:7C"3$3<,0+??=79(AEG67#'
@r8452
TGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATG
+
F"1/#>&&A2-,>.H0+?,((8D',<&;,?.FEC)B&/2;AC:71.359(@CB!.79:1F!4G-/#H(1@$A2D5%98"@F(;.*,7::6%'3)&B5=</B%HA97B&=0)'*'%D7*.9F>%D/$8)&"F#<>.&)E%-'5@$?%#8".6"205#HH6$9H$"BH>3!=;807"F>4%C1)"&H6=2):'AA7B!$0.HA$058!)B!-201A?$F8*?A:%62C&
@r8453
AGCTGGCCATTGCTCNGGTCGAAGAGATGCAGGCAGTTTCTGC
+
7<9DA;+&!$%073(,4?3#<%&6"5)45#@+*=8-EB+1):6
@r8454
TTGATGACACAAAATTAGCGCAAGAAGACAAAAATCNCCTTGCGCTAATGCTCTGTTGCAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTTATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTT
+
+!#*$%+$"&##&$&(($%)$'%!#!(#(&$)(!**&*"*)$*"&&+*((&#)&&()$("**%+*!"#!)+("!'(**"&&!"))+&+'*&"!)&#+"+$+&$*&%'"()'#*&)!#+"(!+"*"'""%&+)%)$!+*#"*)%%")%**('+"')+"$'$"*""$()%#""%#$%+!)$$'*%()$&&%*!($%++!")%((
@r8455
GGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATAT
+
)9#82&CB)*B&(#!<="E53&$=.F:B**8:5)-?>.+(";%(%+@;)#%0#.;E:
@r8456
GANGANAGCTATCGCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATA
+
)&'()!(*&('&&&+)()+&'"!%&+*(")($"'+!%&$%&!##*(&*)$"(*#$"$)()%('+&!)+#"%+&
@r8457
CGTAGCNCNGTTTTTGTTCGTGGAATGAACNATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCA
+
*%*%!'"%"+"+*($"+"(('+%&+&#!'($)!$"*&!'#(#)'$#!%%(&#%''*&"!+!"!"++"%%)&)*&&)%"$&)"'"%"'!'!
@r8458
NTCNGTCAATCATGCNGCTNNCNTNACCCGGCCNNCATCCNCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGACGGTCAGGTAAGCCACACGGTCAGNAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCNATCACTTCAGCATCCGGACGTTCGCCAATTTT
+
"!*$&!*'((()"'#%''(""%!#")'&%'$**!!")$&)"+#*!)%#'(!*#%$&'$*'()'!!)$&!$'!'%&'"+'$%%+*'""$(!'!!&&&+"#(++#'#%"%*")&*$*#!$*)"$($%+'**$$""(##()&'*#*+&$((+!%(!(%$!*#")!%'+*'#!'!(#*#
@r8459
CTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGGAGCGCACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAA
+
6EB5#F7=G305"AD".4<4@>;#@);662G)+80'E?:!*>8A'$H/22B>#:4$?"6*F!H=1$5">'1E961%,88EE@,4/7;;1G=>D0&CB.3:&;6G:3<"/$4C"
@r8460
TNGCTCTTCATCTAGCGGTTAAAATNTTACTTCANATCTTTCTGTATGAAGATTTG
+
#!A71,:&%!6:=8DC#D"2,'8!HB/C:.9A01(3=G9?2=5<G=+8*%<?):1'
@r8461
CACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAG
+
HA1=6./!3G(:%>'#6H/#>!A&8&.B34;1"3)G=:H>
@r8462
TNTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCANTAATAGATAA
+
ED:F@<DC2"G>8);>-E"+>?>D5.H:;?::!5!7)1.!(3!:+2H#>#><?7#=*!+.'1:8<HA4!8F1A/B<0>)=:4&9@,**?&;)5+4-F&*
@r8463
GCCAGTTCCATNACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGA
+
?>D57'(84D/+/'C'"76D?(=(/19CC=%/H7",<:F(7)(&5F?0'7=!":7H+E%,0:;CB=+
@r8464
CNTGNANNCGTTGCTGTTCCATANTGNCTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGCCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTG
+
)#%($&*&$*&**+&')#)*'("%!)*'"+)#!"'(%"(+)%'"("'+#(&)!$*$*"""+"')#(*$'!!#*$)(+)"(*#"$"+$&)$(!"!(!%'#$*)()+
@r8465
ATTACTGTGAGCCATCATGACGCTGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGAT
+
.%,/(@H(@@64!1(!B#6,??/0E@-.G6./,"9!@D#$A=."9,3G;#<!?!#C%*G:2E5'AA!;!*+G%D9-8DB=8+=1GB2(4A-@+"7$(A45DAHD$/85"G7'(.4>.=4?)FE$C-'+.DH9>$8GCGD1</?5G@99F0:E:)+B,DD/F<*(5(588=$,D61($8H#.)7@A9+<HAF!E$2E5=F7%0(=+B?(=(;'B73.7>=E(%5A<3'G);H9D
@r8466
AACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCAT
+
=!?=,F*6"3!44+"(2.(@402C$'6&;B7+H-#D)?'@E&77B,;;<220+A.1A/=5.DAF874G9%2F)E&/$C747C=0H1?E(&7EB2*6='BFDD?/'@'H;D
@r8467
CGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAG
+
G'DCH($!H>CEE@,5*>%+-9*):(;E#6A4-#,E-<<?E6D"+-E0>5;'
@r8468
GCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCANTCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGT
+
B@(/(F)*.D+/DB09-*4A??!1&&<*6#D@=''!20=HH:;DHA&(#$"G+(:+>"2#A645:.4>4-:!C?%C:2+->/28D10?.>3"'49&H:F'DE.+7+;.+9885=&-->0DG.%2?+0:B=41FG/8$2D?+;;?8:2GC2G",2F$E0F86%#.*;A<#4<0/H1%08.:*%?F#CBE'H(7F%HC$*?E!E3D(11>3F
@r8469
GCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTATATTTCA
+
<9/1E/@8(?27F@D!1H=/)5B1FHGE9(,*-F"4+6=.33?'?6=!E*<=F@C6.C)B<"E*+%7BD/0;&/)H46@
@r8470
TGTNACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCNGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCCAACATCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTC
+
$++"'$$"'")+#"%(*)!+)$#$*!#)$+$!$#$)#('&(!('$"(&"#"*#'&&!'!&!!"**#'$!#*'#&)(+*)&")&'&)*$&%'"*#$#(+!&%'&+'%"&!%#%'#&'"*+*)($"*$''&$+&&&#((*"&*()$&!#$*#%"&$!(%'$$%#%%*'!"++')&+#&!%&&*
@r8471
TTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACCTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATC
+
&+"$)*%")"+%"&"*"'"!*)+($(&!##'"&+'+!$#(!'"'+"&*+'%$&$$+)"#)&#!+#"$!'++"#!))***
@r8472
GTTAGTGAATGCTTTTGCTTGATCTCAGTTNCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTNCACGAAACATCTTTTCATCCCCAATAAAAG
+
GB844?D48DBG&-9("%(F/EGE*-<B+&G'3(5-,5=>F<1A&G+.C?:$?%8<A*C!#E8!'%!H85711@.E')/'7:6>(%<@A0,)1D!!%06
@r8473
TGCTGCTGGGNAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTAGCTGACNCTGATGAGTTCGTGT
+
##!*+#!(*&#'%'&)+#"'#&'*(&!$"+!$')#%*!%!)"*)**(##&*#!+$&%+'"#++&%%$$&')&&%!+$+"$"!+&)&#'"""")$$%)+$$('++#""(!"**)%(*+&"#*&(#$##'+#($''&'#($'++$$+($++%+#$&%#&'*)&$%(*%%(%+($'*")&%+"+#)''"#$('')%++
@r8474
CATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATATAAAATCGAT
+
G=:@/5&61E="4#/:''412E<G3C?D83?&(.FC8?GG4F-:)9*&)3
@r8475
ACACATCACGCATCGTTCACCTTTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCNGTTTCTNAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGG
+
<'4C3&E&"G%"H;7>6D;1E06$&$,+$1$5?5$14@%46:>?-#,!C0@66(88'6%$$':4'!38EEA,)&0353BAH=7:%7("$.(=8'7F'9.%:/>'+&D<A+@F/:.CEH=19#?#+A/<A5.&-;'3=&?;B(;9&-C6:"9-7A9,8(:+;@><08<3/C-4
@r8476
GCANGATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAA
+
)%"+""#*"$$%"%$+&"#$!)#*'"((('!*)*((#)'*&)!)'$%$%(!((')%*+"("')*()%
@r8477
NCTGAGTGAATATATCGAACNGTCAGGTTAACAGGCTGCGGCATTTTGTNCGCGC
+
%%$$)')))+*((+)*(%)(!')!+((("+*%&*)!&+&$&*"$&($*')#+")+
@r8478
TTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGNGTTCATACTCAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGC
+
F51$:9)<$$%(.<+5/996+;9?=5F<=1G=@&C0=0E7;'!$%>@C/?:*ED06-E0+G,->6,@7)?>2@7+:%D"7C+7052DC>6ED2E>=058)?&*:BA8-FC)0)F'?@"G&*@*:@=4?+.0=%6-7GF4%(:&(:+=3AG8=:B>B*7,2H75$B3G+..@6:880=:%&.6B.*%.@/EB/B.A>?*,1-'>(@"6#+%DC#E1H;=2-$2-G-A*;DG
@r8479
TGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATG
+
*+0C98A6F<=1@@!5<130!@FG*?;;-6!0)E(3;5:&6'4?C9&3%D@C'#":"D<
@r8480
AAGCAGTCTGTCAGTCAGTGCGTGAAGCCACGACCGCCTCCGGCGTGGATAATGCNGCCTCCCCCCGACTGGCAGACACCGATGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACAATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGNTGCCCATATCGATGGGCAACTCATGCAATTATT
+
?6/0+#,:;$=>;6$D2:$"E?8.?9&0EH*HBE8<-48A5,B0*!D5+#;3>;=.9"#4$4B9>,,./@-!+,G<?%/G*6,B.**=+6E'C?/7.50B%;=<A/AEHH,@*4.(90H0-!$$'F/8F'H%/&/"912F**3??>)7?1?#;?4CB<1CCF45)('74=96+:HD'@%A,(H&!>&>*824>+/$?)7!$2-DA3?(#(9.
@r8481
ATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATNACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTA
+
9@;/%8#"/*'E<3(72:,,!3(A5*%G4+31D#477;9&7A.:?)/?HG%;-/EE0$"7H4!:%'D()H%/5#!F?;7E*3=+H&15%"B8(#8<.0076(%=C@'F4#2;-"993<?-=.$%0."&C
@r8482
GGNAGGGTTNCNTAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGTTTTCGGGATTTTTTAAATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGNATACCGGAANCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAANCCAACCTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTAAGCTGCGGCCTTTTACACATGACCTTCGTGANAGCGGGTGGCAGG
+
*(!)'(!&&$'&%+%)&)&&!*%*+"!#("%)))'('*&!#(#%!+$"%+&+!"#%"%%(#"($%$$)"%*%#$(!&**#"#&$'%%*(#"#+""&&*$**$&(!("+''")'"*')(#$*%!'$&!+&!&($)!)"+##+"$#+)!&''#'##+!$&+%#)"&#$!'(%'")**((++!(("(')%"!""!(+*$'$'"+&###**"#&""+'%'!%')(&""'#*(%"""%#)%'"!(&&#!!!)%'('#*%*)$!)"$$!%)#&'&)(&*'""%#*$+"$&%'&##++*&)&#!##%%*&!&'*#)'+!+(&+&&%&#)($')+"+)')!#
@r8483
AAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTAC
+
,3,'=G2")(2="!!'9#<@'6$4"B3!C97-(E@)>:3,!9&/D*/>8$;')3C.6;<F2?(==2FB/6+A
@r8484
TACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCNGCATCAACTGAGGATGGTAATAAAGCGATGAAACANACTGAACTCCGTGCAGCCGTAC
+
1*D+:22,/G7,G!H/8,5#0;-"/G,5@)(=$6'3>,->+EA'@&:G;G=0(;5@2225"1G939(,4**6$52?,%(A(9F!"&:B?F!'A56$3AF<A
@r8485
TTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGG
+
42=!5G5,F.H>%.E1$.=@)$>-0"=$G2=H!F!@<BHECE76/<)E,2G&
@r8486
GACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAA
+
9HC&8"=1612>37@,D;6!0H/0,$,%8*F469*&D.D2#?::6)B6=-:D4#<+>1;>6)6<2#?%C7=&<0=>1:"?<;*2:
@r8487
CTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGA
+
0D<;>(A+:,B&AE9F9:+D.3G/'&DC/,83$FB;*/F,4$G9C-C9##:;B@0--C;#>7BEF8='3DF85;GG9:"@F8FED&46*2)7.@8,&8>A265</,>?;8F4FE
@r8488
TGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCAC
+
<D8#E23A#%>/<0C-3B4.@<F''H8)@5EFE*B.@*;B4&&5>;>#'95CB*/E1:B/?2&/F.+/8B'.>2G1.3D$5?
@r8489
GNNANCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGNTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGC
+
("(*)+(*+'&%&+#$&'"$*)$(+&$&%("*"&$)!)!+$&&&'+(#(*$!('%)%'!$&*#*##!*+*'"+''**))%*'+$&&&)*(*('*$#)&')'#%''!*)+!$!)""'"(#&$((+"&'#%&%$"()%$$(%"+#++***"##((($#+%%!!&#""*%*$'
@r8490
GCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGT
+
-)A0:/'FA6"1*C)4.$30C!8(><DD85F5&7(2?*B"979>@.AF*@+C/;+=7664+<-"3B=)($228A@(#=6:
@r8491
GGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTC
+
"49+9=(*8B%)B77"C$9C$:B9F$>(A.2;$=G(F-9)C+G<+.F<>#7!24;4E&E"!@$G0!9?!8&!-825.4)(E5D2.
@r8492
CTTTAGCCGCTTCGGTTCATNAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAAT
+
3(9C1/!%9FB2%47>(9)8,B)<%345HE+?3+6:C%*.%%;H'1/8E"BB!B*G=8E5F4=<5
@r8493
TGACGTTACCTTCAANAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTNAGTNCCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACG
+
=.="4+"20#!*=E!$($E(9AF776$*0.52>3'#%B'="2'&04:<46B,7G4&<C/6F*,47B8&4+A.9,@161-,D.1/#?G9<=@-&/37=9-=(AD0C,A4"D%@9FBC689H..7=(77%GC.A>G.3G,:.H,-D3EA.&88*9/GD4>3"19'E,;+**.4DF7C#(,/(''FG(&!)#!"3.E6:$.D>9&*<!@C8!)G5>26C%+
@r8494
AGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTAATAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAG
+
/?!/23;1H)02:?E:?B5183<)%$><@4@,<1?C4B=:HA-3AE,-35,<D8:8>!#!F>B:@@%B=;1=@5-C9$,;F/+CC/F?+C#=4/AG*1F)/(4)&A"77A$'B#?)#8"721$&&?-G@GE+F4,A#,"-)0?+-E2CF77;"59+=FA?+50%=:?3:)9$)&7;!/%(?62F.5(?%
@r8495
GCTTGATTTCGACTTCGGGAGGGAAGCTGCATGACGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAAC
+
+%&*)"&+#"!*%&+!*""$!+"$"#(*)(!%*)+*$&*+()+&'''++'#($(%#%)'%##!(*!#$!$&%)%%'#'"%!)(+!!'&##$
@r8496
CTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGC
+
3HHE@@8'A7@+4,=8)>/''--17$F@*."32-8=$#<(++"$D7=
@r8497
TAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGC
+
"H$>;,.#,H,#"%5B*F4!:7;;?;51>A8%.27$%(83">-?,40BG?D7HG@B?89/+F(<2"&H8-'5=3:G./G)657E=6H73@5HD>&G"B@B?G717.5A1@,
@r8498
GCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCNTTCAGCGGGCCATCATGAATGCGATGGGCNGCGACTACATCCGTGAGGNGAATGTGGTGAAGTCTTCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTAT
+
?1@>8*!=4F&/,008E!&G)7!.A3F+C#"'%3!/6C*=<$;E2&H<#6&-3*6+GEG<&$&0(?FH=$(<4376'2$/54<E#)#93&0+E-=<?!$2EG',!"H%##<954"63>A,8:DB6/3)E@H7D=4H@F().10&&-1BB+>1<DG%)/*6+>6;83A+56?*("%9F"?23@H!/D!/"654<GG4)F67>;#B/0#"%6,;F'#;2(7!B(&*@91A*@,!
@r8499
AACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATACATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGC
+
E;&&2H-+%%913$@>6G014E%A-D9;FD>0/&4*;#-&?&+(+*)1<<(=>EF#=$3(E.0D;59D-7$;C+</,FB2!2/E(43D:9(@!
@r8500
CAGGCAATGCATGACGACTGGGGATTTGACGGAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGA
+
H:H&A;:AEF!@7(?6H,3AD4".*A1E)4A;-=-2!>>1B@;F84,;4#<),*0%E0G)4;%.%#A9FDAH0='4E;&!*E.2%:H;5B%'"6C$
@r8501
GTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGG
+
HG'1'<)#:$GD&5$)H'1'2:2"%;(-/3*6$E:)2593:5(&/":)B+%;G.*7;4'>@3$><82>C@6,#.3%5;/FA==&,.A2'D;&/8HC3"87.C)>E/0!,?)>'A,H/,7*?="CC%C+27(6*=*3'1#!3+H.7(F;H%E(C'=A&A<AA-D@%BE%8&;HCE*AB;2-@)17!F5560D@.=6*1"<
@r8502
GACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATG
+
/5BE%>':C"A-%H))?=<E#E,/#7A#C!-<7'4EH/C38D0<'::
@r8503
TTCATGAAATCCCGGGAGGTAAACGGGCATTTCNGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGG
+
90*))265D&H4:?;7F?"*1???4%G%9=03>;#9!+DH+.&(.#B,B+)<!;+-"F#2/*3,E?<,H=,!D7+86DBA:04FB#1G1.(,G5'@$0DB?FE.,)"A2/59)>+))G'A)$0>)+6:B)1",C97E"'4+G@<3:%//E,1CA
@r8504
GCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGG
+
&>D6+'*A:+6,#:D"./B/4%-2+(39C>>#.A(H-85&G9+%07'3<%+/
@r8505
GNCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTNCTCATGGNTTCCACGT
+
&!1"-G.0EA@:+5,7)&%/):%.E2E$%B,'+#5,#='D!/2*!!=.>8D+7CG0.<3-(:;>HFH0H@;:&$::F>6
@r8506
TATTTGACATAAATCAGCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACCGCGC
+
$1-%"1$$7"30D?!%G6:7;*7.-!B5"3"*,@G&#3!"?'0=/D*>(G,!G44.1#H13,<@@E?":)E+:%BG.*
@r8507
TTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCG
+
C"A@76:<"G0);8D<>*H13#@CEF@(!3+4A',C?2(=0#BBD8C1
@r8508
CAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGANGACGCCGGACAGCACCACAGACCAGCTNCAGAACAAAACGCTCTGGTCN
+
EA2*H$@&&C",:/;=';$4D/;:.$1*$+%)GG22F@'>@)8?)H>%3,9-!C2>133<.HG'&FC.+1-;##:3G34/$3E<,"%736">)G;:#2?F#)%$#"F(84@D:DH#+81FE+--#/FF.C
@r8509
CTCCGTACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCA
+
'"&()&+"(+(*+'##*&()#$)"*('$('*'!&'+"'$!)"*$&'$"(")###'%*(""+*""%*+%&+
@r8510
NGGNCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCNGAGCTGACGATNCAGCCTGNCCGGCGGACGTGCT
+
&))$+&*!)#)*$'""#"'(+%"+"$$*"&""$**)%(#&*+&$$*(&)#"&)$#(&!$++*$)*#$!&&'$*!'*
@r8511
NGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTC
+
%97/E3%*0$+A@=:&D";2@6(E6$A=1C-24&CAA#=C.?9A($0@$.9?:1'F9:$<@.)1#@0E9<89!#;,+>"H2,(9;!@6&1.F)>-2%D263H@*93
@r8512
CTGTTCATATCNTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAA
+
>@'1<82A@5<12!B--4>A3/+7:;8DF5/%#D80>=<20811?=)/>
@r8513
CTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAAT
+
3H$.57F@B!?(E;,<+-3:-&EF.C*%9B'!G-9B/0+&,B<0->3510#G+$+12@(7!1%-%G
@r8514
TGTACACTGCAGCCTCGGTATCCAGCACANCCTGCACGGACAGGCCGGTATANGCCGACACCTTCTGCGCAAACATCTGGCGGGT
+
G?(B/A#/980"H:4$B'8F/2715A#FE%)/<&1B)(0G<#1&!H12+5-E:F%E?#2HF:G7*4>E5%:20;:;H65$>,"%B
@r8515
TGGTTGCCGCCAATCGTATGGCATTTATTGACCCGGCAAACGGGAATGAAACGC
+
4,(!4@3#6D,;9*2E+G(*<@4D!,*+29:3801=>>,<92HG4GH)"+"!'8
@r8516
AACCNTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAA
+
'**!$&&)#++*"))''(%$"%"+(!'!(%)#()%%$"*!'%)*)")&***"()(*)(!'$+!'%$+$!*"(&!%
@r8517
GGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATT
+
+'"&#'&$*)"#+*(#$)'!(&#'!(#**#%%*"!!!"$*$#)%$&
@r8518
AAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTNG
+
9CB6(4!0&51GH-C)=H26##%#-,3D"42<6B*9)1F?673-+9811'8D-.CHB3B
@r8519
ATACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGNAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTACCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACAGCAAGTTTTGGGTAGGC
+
$%CC:A$'E7%E>$<.3439B7*7E@'G,+8>=*,/=G30?D9+'DD1/;(AE675H)$A5-6:%-1G&,#CEH'F-6.4C&=5*8E1!275H<2E.(C%%C@955807,<:-4B>=*B"C888B1CG/7">EA7?4E;CG'@.8&,)&,@?#1?49C$%4*?F=G+?)3%38H=.:8AE0:A@6%3:$?8)%;,!B4%7E=,H2%3'#.'FA0E?EDC;2A&<'C*@FF&);7=H-EG;+!,+%/7!.(4DF!5+#
@r8520
GNTGNGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCNTNCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACNATGCCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACC
+
'#)$(++!(!&%%(""'#!)!**%'+#($%*!)))%(*#%*)()%$&"+*"'%"&#)(++**+*$*)!"$*((#!!#%#%"*%$)*"*"((++$"#*((#%*')&'+'&*%%&#%&%+)"'*(&!!##&*$))$#+#!**)$$+#"$'"$'*'(!$&!&+$%#(*$*!+#$'&+%$$#()&****%+&(!)()'")*%''#%#"&*#%'(*('&+)&*&#$##'((%((++#*
@r8521
NGTTTTATTCTGAANTAAAACGTCACAACGTCTAACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTA
+
&B&#=-.>C;75-)8<<>?=9?F()E;#G%12+-08;&:,5$5;E'E-99B>5-GAD!G""09-5!;11/8</&"@58+@7*(F>&&39)C33=(7?G;C7
@r8522
GTGCAAGTGGACTCGGAGCAAGCCAGCAGGTGAGCCGTAATTATCATCTACGCGGGCGTAA
+
.;F$<>,?<FD5'+(H"A*GAG%':GGB3&</:==-;,2@:G*"0C%12+;!86$71&:,5
@r8523
TAGCCATTTTTCATAAGTGTTAACTTCCGNTCCTCGCTCATAACAGACATTCACTACAGTTATGG
+
+&!#%*&"#'')!!'%##$'!)++')(*+'$(#)&*+#((#)+(&*)&&'++$$%"!"%+#!&&$
@r8524
GTGGGTTTAGTGGTTGTAANANCACCTCANCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAAT
+
5.E>BE:386=:5:8,G/G;6D78$;$H(#A5<A#,C1;?2)'8+ABE7&0;6#)3$C3-17,-6*21+*&(*B%G*:!;"5G??"8)4"/F23E?;0"A5<)5!F<C1><;.!G;H((7!,E>:32#%)
@r8525
AACGACGACGAGANGAGCAGAAACAGAAAGATAAANTTANGATTCGAAANCTCGCCTTAAAGCCCCGCAGTTACTGGANTAAACAAGCCTAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCG
+
+!'&+$!#('#!*#%)$$%%$"$"%'#&'*%%&+&*)!"'*#)%!%$+!)#'+&%%('%#)%&+'+"()*$%"+$!"*'##++#!#$+%*(&*&#+"("'+$$)*+#)&&&+)(('**"#)&#*%*"
@r8526
CGCGAGGTCGCCGCCCGTCACTGCAGACAGCGGGGAATATCAGGTG
+
4A@@G@?*E!4==&87-'$@!D$5)/"@&9B#-"="8!H;D7*5B5
@r8527
ACAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGT
+
$E59,&0:!!-9@0?B-*2+$E?@1A'2DH6@!:4E3=@=9%H;"?D!1)A#%?F(
@r8528
ACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAANGAGTTAGCTGATGCTAAAGCTGAA
+
5>$D*E+F$*4!':)=&02B&@2E7@+;D&:/&8!7;3$0G<$$'F*,9-H0B/?2*E'G1*&C?C6*2B&@3+'/;AG0?@+.!!&>&-9"
@r8529
AATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGG
+
<ECED@A%5*);-3.)B)2:#,./072F1A,:(B5#+&9B6EE4:''+B(9#=-5"F@:<72)8A8A:,.,F&,#7)/%:@=3@#9C7'D%-=F?+.
@r8530
AGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTG
+
3'!57A8!>B5"C=#34/5#H7B34<F:G(B1+?'<@D/&-@2$>B.'B
@r8531
CNNNAGNCNAGANNTNNGCNTNNCNGNANCANNNGTCTANG
+
!"!!!$!!$#$#!"$$""#!!#"#!!$$"$$""#$$$#"$$
@r8532
TTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTGGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAG
+
(9%G*#*A-?>>%E*88#@*+=@6$.($&0)H)5<FB/9;=G2?3&=:>12G3@<D;"A:;-CBD*8.1+;G!=9!5.@72%187-"<>6/>C1=@&4:&0H))C>C,=F5AEC4=472C"C#1$!9*7!=+>4C&@E.D;/9>.38/!-&4(4*,36B'58&6#.42A,/&&);AC@'B?%2>3*8+7>
@r8533
GCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCTTAATTACTGTGAGCCATCATGACGCCGATGGACCCTGTCCGGGCGGTCTGCGTGACNAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCANTGCAGTTNATGTCGTTNGCAAGCGCCCATACCGGTTTTATG
+
8AC')542&>1/H.&=.-3#*,D"6#)*1>A3!80,FGC%25B6)C"*FFC$=&-3-'D2BB1!'.;E)'0%H";E.E*18)+:*!!757!-/:;":3%CA%CA)99G0**(A,%$$=E"='@D*40E.;3FC,&3H**:E!H7:+:;(!.E2</"(CA53/D5'!A'EA*%GE#5F-F!"7'&FEH8+G@-6*-?#<$(=$4A9""B,C>?>*8/24=F3)2@%06$7601/"=2H<><:GE4*CA:+B/B$'-:4@6*".0(3=5FGA&()9@5=19!70B9H
@r8534
TGAGGGCGNATGNCCNCCAATGGANGGTATCGAAGGAANAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCTTGAGTGCGGTTTTACCG
+
&#(""!%&&$&!#*'!!+)""#$!++'"#$*'*)'%*)+&!'($(+*$$#!%"(%&+#")'##&($'"+''#+(&&%&&%*%)!*+$%'"'$&*)"#(!)'%#%#$(&#&%%)#())"&"
@r8535
CGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGA
+
H)(&H*35'4=.%F%2,>=>:!7<HA#;(1-83;$3A3*;*$?!G2A"?6.H14'@-=+6?)(&G7/?F9"8%A!+/4+
@r8536
GTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTNCGACAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACC
+
G@?1:F04=!F0'AA5)%7C7:,%34:$@#)>BG72'61=B!D'0-E,F'+E6:-70$)'6##6??)>9C5;6*4%H=6?)BD4(BB;=)$99$H<87B9$>23)&FG?61&C>0<H$H66-0+8%G&%9,905=H+<;";+E6;4D-.8?+!)()!@9+8>0B$B$05@0073((3D$"D-9>0?1B1!3<$/@,*E95C;#2;:;*
@r8537
GCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTNATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACACGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCNGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGC
+
2E784-(!:#*18B-620$>D2F$F.()0#'1$F')?:$G<0>H6665$#'"=*"-3&7-?E</B9$+@#?F(-5%@)EG<;&.F>"CB0C!0),/92E7"C.74@B-71B'4?G'!A;3=46.C<=><H@-3".&D1%-(#:.1"A<F?+$G1(#1>@.?528:B(#@57&>876+/7$/@=%E@C!2(%#1.)C60AH9'=<C&7,>:$80:(85D2B)E/B$6C0F09,F6/H%HH;*-"&8:"E%85E31&B*)56:<4%5,"=0-#%C>?=@H87,%3;-19"%((E4-1;2$$7!C.<:,%,D5!$$=A"!.4.<4A;<
@r8538
TGACCGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTNAATCGTG
+
12!6@9"E8C*-E#8;6B,7.G@C3-#4G),FH''3.1B&B9H+.#"8&-#?-:,3*;)AEBF&1"$G!F/D+5$/G&>2&@?:
@r8539
GCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGAC
+
HC)F7$8.=H9>B9.B-/9H8<3'('>'$)0F?E%#1+B#5G*C/6'-(FD/
@r8540
CACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCTACA
+
+.6234C89,<CB?@"2/>@0$<G@.<:#,EF6GBE4205(/!D54.=),(3
@r8541
CTCTCACGGAAAAAGAGACGCAGAAACAGCGGANCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTNNGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGACGATGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCA
+
$5:*"H;3.E%F'=B1!&331-.?F!<<3?+G-GH5=5DB8>DG@+($@*+((#'78B4.A:@$#*)&!<1?A+1('H,8<H?:.8"9"#3#DA.B@B)0FAE)'>F#CD!/<.)+20&*(*B1@?)"'70.EA:5.50>DF)=<,'>B-D.+&#6&AB%:#-(B<)8*4=!-=,).-=BF>7=$6:!=*;<91B0+F1>%"4?,??G
@r8542
GTCNATTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATTACTTACACTGGTGTGTTCAGCAAATCGTTANCGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCTGGTGCCCCCTGCAT
+
(&'&!'+$+)'&%#&('&$(&##")!#*")#%!#!$%%)%##&)(*'#*)$)'$"(!$)+)"$#(""")($&$'(&%++%')$("*!'+*&)"$!$$%!)%+(!%*#&*")%"'$+'(%''+%*"'+*%$!$!+&&)&'")%#)%&#%&**%&)$#!!("*#$)''"+&+#!+%"+!"#%"$#+#&%#
@r8543
GAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTA
+
6+)?<!)8@?><);-<4?1?2?0((45BF@#"D=E<3:.B$1?%=76"-/1#)%G.#*-E:0A>8;#4"=1&3+;4
@r8544
GTCAGCAGCAACCGCAAGANTGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTT
+
A276@-"6?.C%A6DB@07;-?0;/+ACBD57HF5<+?!.+-;;-?C90=3$+:(#$C/54$/(!#
@r8545
TCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCG
+
-F5$-1A4C%&E3/'EC:;=6?DA"&G.'FA&?20.+73)9!!B<46H84.&AB$>$C4(D37>7>6*@*4*=<-:
@r8546
NTCAGNNTTTTGCTTTTCATGTTCATNGTTCCTTAAAGACGCCGTTTAACATGCCGATTG
+
#&&)$(%('%%++*!"!$#()%"!%"$+))'$%*(**#%(%!+%#(!'!$&(**"*%!')
@r8547
ACATAGTTAATCCGGGANTACAATGACGATTCATCGCACCTGACATACATTAATANATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTT
+
BB2?925B)2@?'>(=),33('05F86',.1/=;7G>@+5D3B>>/!7B=:E+E5;5/>8DD@&4D049AF5:<:.8=5:"?AH6/8=5F5,>:B<$!9*+&-.@B
@r8548
NTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAANAATCTGCGGGTCANTCA
+
(E%,6@=*4#6;:5@8D4*"/H7%@/B./$9%*<$E63,7A?&/E83F-)FFB-8<3$AD?&?0!2D=A=13+$3D>@$-3C>;;
@r8549
GCNGGGTCCTGCTAAGCGCTCCTGAAGCTCAACATCGTCATCAAACGCACGGCTAATGGATTTTTTGCTGGCCC
+
""#(##&!&(*+")+#"$(!)'%*)#%+#$!()!+*+&&*#+(!*&"$+!%%$+#*()*!")()#####!*$(*
@r8550
CNNCGCNTNCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGG
+
*"($*!*'#!%+)*%#&(""$'%"($##')$%"(#*($+"!""'$*$(()(*(#'%#%()#$"#+*)+++$!'"))('"+#)!
@r8551
NCGTCGGCNACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAANAACCGACACGGGCAGACNTCACCACATTCACCTCACGGATGTAGTCGCTG
+
!+)+-0C9=89#4?;3.*A!C;8E+=D8C0&D:E%5+H+!:B<+)@-"@9*A/,A)A,G5F6>0(2+F>4(4+*':&"H53C%,7!+0:0=AA0'37/4'-C#E!':14@#HF6D=3)@)E>.B#(HE
@r8552
ANTTCAGGGATNNATNATCATGAAAAGCAAAATCANCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGANTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAAT
+
"("$$'"&'&#%!))&*)()+$#+'&&&!&$!$!")*$$%))+)*+)'*+*(&#%$*'#"&%$"*'*%"*&%!*#&###()%!'*+!!(&'#"&*'&*'!(+(&(%)%%%"!%!&""!"'$(%*#(*!&'#$*+%($$!#)%&$&($''!!*
@r8553
TTTATGTTGAATGCCCGGCGAACTGGAGGCAGGANGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTACCG
+
1=)?:=(#$5.FB$1;21#G:7D0;"'5'*C2?H8%%/;,C(>82?-E5'3=1?2$@+AEG?3B7,+0=<%1(.64-0&=-8<3:%'$3:@
@r8554
GCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCG
+
G<(,<A(="092BB:C,80,:C(.??1)B4B&2/</?8*22(;G6BB:8!3*7!'GD+#0@5A415/,4.*?)56'0'(3/GE8=0:@3B#0@
@r8555
CCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAATTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATGCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGG
+
1-.3A/*H8E89,"$)BA;(#!0F7'+!=<F-)>'6(8F1$)GH7&'/F/$0CC%C9)92F075%$299)-)1*8-8;?A&H1C"BG730E<7+=B!B.,:E89?F*'.@!@%2=CAG1=/8&85/2&,.2H4D06:AG!.2?).BH#@C28;>0'@,A75/:90/9#.&2FB''H.0864@>:+25#%?0,!,=>B%9*EF?&/5"),
@r8556
TACGCTTACTCCCATCCGAGNTAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCANTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGNACAATCGATGGTGTTACCAATTCATGGANAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCT
+
)F:*B/"&/5:%$230!+=@601H!..<4>2..>%/5/0G6://'5.:3<#.;(*?-A$5278=7A'$H;),EAH!.27B&F%5#=2HC7'"H1A48C?=<>*!A5>%!?H1G=D3(D@G>;92C5;H"F.:F/-<6>2,A@98>>4F/<8EH(%.@<@:>C310=C!F"7-)E<--F'9D=8'&E&'D3B7B5)/*$F=-?=?$@!CHD6@)0A-'$/7C:@1E.A:.--+-;H!%+HH-A/*-3=)B$8=9;)#&F#B'B($+9A*.,F""7.9$'!A:)%1D&0,5E*,.7)-%>;5
@r8557
TTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATC
+
)473,*."<+B68*.-&9G#&2C'AH1C9A+>!7%A);HD1.
@r8558
GTGGCAACGTTAATCACTGGCTCCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCT
+
?23;&9)(-9C*7;':D;0*$#*@"'*@.A(F0+;EAG.77-C;/>;EC<;9E/=D$(!#'E:@!.'(<9(B2213&
@r8559
GCTACTCGCTACTGCGCTGGCCCTGCTTATTACANGATGTGCTCAACAGACGCTTACTGTTCAAAAGAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCA
+
DB.HC!+F81>HF!##!7G:%*:9!5C?1H71)0*$#1$)!+H:);">@'*)G$%*4=B+8(C<1+*;+%:6A85,#!5(+"*7#'B%)%>H$:9C-=<D,/367
@r8560
NTGGATGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGNGC
+
$'B>%-)<03">$*DH9@F?:!B66:2#E#7@'B-98F"3!%45?7@?&5,E1B('
@r8561
GTCCGGTTACTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGT
+
62(<#;!.,*/D8;"=E3B$5)8<C$2,37:<4%CG<E)="E!E6D*!64A-//6-&*'@*F-)51#E.<
@r8562
CAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAA
+
/"8D7:D-=20<):.5-21'F+;)4"B:%5CG8=3)1'@BA3
@r8563
TCNGAACCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTCA
+
$(!%#''%"'"+)*(*("!#!%+$#(")#!&%*#%(*'%#!$!(!#"#"'#$)&#"''(!!")$$&*#!%$&*&"!*+"'!('')(*#(%+$**$#(!+'&&'%)"&#)$$")'&$&#%!""+%'+'$+)$%)&)$)'++&)#)'(%#()"))(&+$(*%'&&!&$*))*''!*)*#+*('"&*")!""'"(
@r8564
ATTGTNCCATCACATCCTTAGGATGCTCTTCGATTCNAATTCTTCTTCC
+
5*/></H$<C&'-6)1%342==1@19B?%>,E8G($):'3/E)(D(350
@r8565
NGGCGTGCNATGCTTGCCGGGATGTCATCCACGGAGTATGNCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATNATGTTCTGC
+
(8E+3;F>/:>-8#DH/-8-2-F5*AE<7@F);"35!*HB>0%+.A2<<A+))4"A@E?D-@DE428H?9258)B7&;9)H3&,+,($
@r8566
AGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTGGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTT
+
7><4/"2&7%,28(B16>:9$&59.%''H;%@+<9=(A6;:C8#=!%<(';#-H418.6.;E)8AEDB75?F<ED98;C4?406D&'#20;$DE:=#F$=<="5?A7859%>>(8$468>8=5.")@>!;HA<7&@B:9*)D8+;/+F<2-G5.90.,B#,6&@/AB6
@r8567
TGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTNGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTAT
+
7:;.4<&29&*1?":("+%8C8H-2+:2;33&5F6EE!"6$F3=2(!-:>$F)&?CD).%/A"!<8>3A?6'C&>#!&0HG0.%991(%3/>$C!#!737C$30;$>%)E7-#"9?.3"-FC9;7H,A1?H3A&C9%,BA#C(9F!3DH7<=&6F
@r8568
TAACATCACGCAGTCCGGCGGCTCGGAGTGGAGCGTGACAAGTCCACGTATGACTCCCGACCC
+
F?G=1<-$=.&.;)8;4>1$2G$@*/H-D)%3&/*//A,C@F6354@6F"E:?'9<#?1G41+
@r8569
GCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCC
+
D6(+:+,>%4#EF/=,7#$D?E.C#A<8,?+#</?C.>:AE'@A4"C2"F>9#1-2###&"1(=5$G9%,8F
@r8570
AAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAAC
+
G:")A%&2'-<C;)1F#78"?)4FA9;H4C4.'B>-*HH@*<!'(A0&>"/-=5/+>''(8(5=?/>=9@4:!-5:"1&/"+H#2!#-C09687=:E?=0(#(<!=+,=+2/-"5'FA,D>53F?BB46F3@,*D!B)%+=?6*CAB)@0F"?4$,A2#*080)'40*?8+DB3,(@H'-:!F4F/!8.G)F'36?/70$H0D-&5@3E"%F30(01=
@r8571
TTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCAC
+
+3E$E?B19@B&>6*0!4!?FH.<9"<4?2H1?5@:%B6(H%H&73;D.,40@:2C41$D<GG=?'(;!./C#"$:'
@r8572
GGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAAT
+
3G@"0GF5+""!.H5-+(!F/91=7?H.3F-<,BG=9B5G70"E?!!@@32'B<:(,
@r8573
ACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTG
+
DB'=30@;/=6H').)5E162$9F8#$&C5;031&B&1>=@#!#A4C/7#G3">B7>)3
@r8574
AGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTAACTACCACAACGAGCNAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCACCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAANAAACGAGTGGCTGTA
+
,&1F&?=FA6"/<!AG=):371%#3AC;:$1%$>G3AF1$&DG45+-%C58%3B:8D!37BC1;>%:?#=E,15@0)8)C:<#13370!A70$H&"?$;;&75+)'?!%:+H%"".D2EC':G(?387A"@1G*('5;6<D5&A!?">0
@r8575
TCAGTCANCGCCCAAGCTGGCGCTANCTGGGCATCGGGGAGGAA
+
+@A'B2!.=2<$C(%1.12+7E%=H1*2?:*-@,(9A"=&,=:?
@r8576
ATCAGCGAAGGGNCGATTGAAGGTCCGGTGGATGGCATAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAACAGANTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACG
+
:F=*.GA4'G)>B?0!*38(F&*#FH&6-=8A02-9#67G:0CED'B?B%6>C".08F>'BB#91'&G&$!4'-(F:F'*>2$>H&F6$F74"9#)#,@2+*<".8A>H:H+>!G)>++D)AA41D6)?D,%?!&FBE%5529;*>%;:H'!A*)>4<$!H(.A1<7"5&!E&D-B4#(#@G<=!51<<
@r8577
ATNNNANAANTGGGTNGTNGANTGNAANNAANNTCCTNNACTNNATNNTGGGAANACTNNCNTNTNNC
+
"$""!####!""!$###"""!#$$!"##""#!"#$$#$#""!#!#$##$$"""!$"""!"$"$!$!$$
@r8578
ACTCCTGATAATTAATCCTTAANTTTGCCCACCTGCCTTTTAAAACATTCCANTATATCACTTTTCATTCTTCCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATNGANNATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAA
+
0*;65*1(#-8!1,7G?9/#8(029<+3:CG09965?B2=&4G!'<':/6G'*'$!916C!H"H.==(%5#4+3)EC97")E<&$79>?#//EC'"2+F<*=D%/6($7-,3=AB8-;E.CA&:4/?1@5F"&1%@'4-*93(9D!<9;4-#6/+0)F-,C6D;$?A3"986H1CH8;&BH:;E689)?3BA'"C%.74,,-#2/";52,;)D,6B/'G,<,#9/'GA,0:HCCC,%?87)1*9!C(D!3D+6,D.,73"96:675B9F)&HB4115#>,!.C@1'>8D9=@;=B"<F,(/H<>G*3
@r8579
CAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACT
+
%G+H5$'H)/B?(F"H-HA7A,47335-+?%74:B.G<:43:"=-<50-#791);B+C9"B:2CE
@r8580
CCNTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGGGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGC
+
*!+)'#**!"&%*#+!!%")$+'!+&##+$"&%&+')'#))!&+%%&!+"#'!'&)(%#$#)!*%%+%++%$$'(+*('$)"%+##"&#&)(!$%+$)$*("(((!"(!)+$!($&)&)!%%)*+"$&&&(&(#'%%)#&#(+)&%+))&#!+&%''(!(#(&+&$(&"%!!+""$($"*"'*$%*##!%&+"%&&)
@r8581
GCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGA
+
%#+($+)+%&"&(!$%#%("(*(#)*$(&!)#+$"&'"%&
@r8582
GGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGNTGGTATTGCACAGAATATGGCNGCGATGCTGACCGGCAGTGAGCAGAACTGGCGNAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAA
+
$;"F@D21?2CB!F''GDHH.5#$@?<H*)97%2F$'*?A91,B9*B(,/@C0H%0+$#+6F/8'=#BE#77,#.=4H,=798?C#6431>"C.'*+/)'=F<HBGE(5#@/@2>'$?92$.1!<:"&EA61C$3%<>?26,CB',35"F:!5<'&#E90,+#E&'=EC7%A2'5@9B,5/)G"
@r8583
ATNTNCCCGGCGGGCGCGCCTCGTTCATTCACGTTTTNGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGCTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACCCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATT
+
%$!'"#+''$%'''*$!#&##&+#!))!+'+!$+'%*''$+#()))')&#%!%!&))$((+%%("#(*%"*%&'*%$#%*&%#&$%&&()%)(+""()$%$'"&'+'&)#$')"("%$&+"(++%**'&(+%%+&(%"++)*$*!"*)!)"''*$&!#+#$#)$*%#&#(%(*!$*&&)&+'$+*$)+*$+'$&"%*"%()%'')$)
@r8584
NGCTGATGCAAAATGTTTTATGTGAAACCGCTTGCGGGCGGTTT
+
)2(!F#E10!F;D6//$?2;B39096;=A8&$.4B&&#)8='))
@r8585
GCTGNCATTNNTNAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGNACGGC
+
*$&'!*)("!)$*$+&!+**!)*!$$$&*&(#$&&#(&%%)+("!)"'"'''"*&$!#(!*(*&!%!'))%#%%&$')&&(%$!&'%#(+($+%$*'
@r8586
AATCTTAAGTTTATCTTTCTGTTTCTNCTCCTCTCGTCGTCGTTTCTTCTCTGCTGTTTTTTCCGCTTTTTCG
+
D@7;2E+F"'5H6F-6H)"8+G@&DB>'DG+.6A?:;,1"!;4;D4&@5>+6$#30F$3?$7/C$(&&?$#-?
@r8587
NTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATNTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGACCCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCT
+
'F?-1-,H:%17%F-5+-H0,'.&&,0'-E!,E/9294E+04$)(3+=-=:0)+601$BG$7H(&0-$:-GE=#4H4?955$!=1=#:3:D<8-GE@&8EFB."20680#6E&E*67%3?7!))A.H??8+AACH>=64?C%"'=38/16:2!6.99$:F61$31*>"3>2!@G/+7B;"&8"5#B0=F,.&:9AH-&+$8$0BF%$#H9309DG69!&2D22E'E@8:76G6#8C7A:A(@/:#EE39C%57E%F?E3*1H694$*209)1E<7#;+&6.7E8C.>E%+7;8G/1EAC'-**F/HGB<$(&'+<AB>+):*('+G;G@;>">6/E%;;/2&5#1GAH&A$4:96:9+22!D&,%?<?4'"E=H19;77FH#A@BD;=H&(#DD6G7(B091'2)?=(&&+=1
@r8588
NCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATT
+
&3D/->(E;F<=?*:6/.=4HH6G6FE!20GF1"8:*@>>9@"!-=&?85'),&G
@r8589
TCGCAATGCNTGGAACTGAGAAGACAGCGGAAGCTGNGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGANTGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCGCCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAGTTCT
+
AEHGE@4"A%H=1$B3H04&:)!>96?'8'87GBCH,--E8>H-B(H&?=?;:D1:13GE7:H1+@&.>+/?!D(%4)+%$1,@F.14"5<D249#>EDA?>&'-4G-9@;CF%8E/EBG,F#".<@>#68?6#&D!?,E/FD<@HA;?5H:+>25.-CB'0D9>;+86!A"F+43+4)A#331$40!:C!%>'/H0:7B26750=E8?GG6-:"BED@F4<>*<!D6!$%#!H
@r8590
AACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAG
+
1&&+52;9"@-HFAD'6F+CFC2,>*,A$G'8B;;9D",*#*$.B7>4D/HE+3-*D#ECC96GCG@G26E@8*A3$0E-9B42A224/7?CD$8>?&6GEG'5?3D%$D:-
@r8591
GANGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACAAA
+
&)#$+!)$!()$#&+)((+')&)%('++%***%##&%!)((&#)*
@r8592
GATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGAT
+
C>EF@)F*1;FE<BB@',?-56,B$2,;#.>7H#C5A(4+G6,(<>1!=-!""'$-,!76&8%4!6'"B)$=+5E8+.D=9'227G@1D0;1130@?9>D@871H+3:3$6951F%;.D>:)A"C
@r8593
AGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGGG
+
46?%A@+D,(%5&F@>B#E"B&'4(/@0A'$&&*;,"A;G+5,D%H780E@!7'-A(D4";#/31G)<,+@#<)92?,E%4"+E2F.2EBE-4?C,#$'B
@r8594
CCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGANTCGGTAGTAAGCGCCGCNT
+
=+@6!-AE:F,*,"?E+6G41-CF/D5:4746A4@D<@+!!4G?37B"G=C&0%0.G-#G(:F.%:,B)B&E
@r8595
NGTGCTGGAACNGCTGGATGATCGGGAAAGANACCAGCAATACATCAAACGCCGCGACCAGGAG
+
"4/%)=D39<H2+@A"<-$@&@!>C.52!'E$7<%<3=7A)0H.,6-<G$4&&%H'<@-@%G.-
@r8596
GTTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGA
+
;+#E7A3/,G'=<%'.D3/.18D9)%/G-39B%70*(.?>8>8!+B62<;>C;4.)-H=5#54A3$=9FE7;95$A-<%-+!%%6C(C87&
@r8597
GATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGACTGTCGCGGATNAATCTGACCAGCCAACGTCCGATATNACGAANGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGNCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCNGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATATGCGCCAGCGGAGTCGTGCGGCTTCGTGGTA
+
A0>/,;)=E4&()?-'#B7+C2:6%;'AE.#8B,,%<H3@?&A=38-?=+B68=:3+(*$/'/,H(,/'-%1H'8$H2:AG:GG)C),%5/4)=$A9=7D#F1&"1F-#*'538@*>&!$6DB(==-*)(G(*5("C548F*9259:151?'AB4(),B&5E2(&)-9&:@)?('>0%,A1:"!B9$G0#%)E:#$33H-6.25$(8!>;(3D,8-97$F,30@$(<C;-H<B$?9=%BG>&?(03/:AC=3DF'4?:C6,)"(<DH'!#+=1FFF2D/$0+%>4*';C2(1#;>259""4%3HC
@r8598
ACAAATCCCCATTCTGCAATGTGCGACAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACT
+
*9!#,;A8-9-31D>!GCC=-H<*:/:7/18)F/<(+>8+&$:&@,G@&*=<AD),A(D;?);F5!38-%/<B(0F@28'
@r8599
NACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCNCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGNCGGACGCTACCAGCTTCTTNCCCGTTGGTGGGATGCCTACCGCAAGCATCTTNGCCTGAAAGACTTCTCTCCGA
+
,CF5+<$H@"$2/?&(FB55%'$,.5&#4;+;,9G/2:(C;;@G8D=!%A<?(4A$7&"C207</?F&59&,@B:02)5G;6168DC9;HDE@?.!%"*@,&/9H(60)#.?DG9?0<C6>:326D%%44'88$#04;$:-/:!A>BD7DB5%6>=$14:(%%,'E
@r8600
ATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCNCAGTAAACTTCCGGTTG
+
@)%>B=F'3!$-;=#?")F769>0D7?.1"$=-/-2DC-?0$F@!-.@06B(2!,DF
@r8601
TTGTTTGTCGTTCTGGNTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGA
+
D!86:F6#'5F8.3B=<*A6>>E*2D$:?)4#.3%6"#2&</18G4)!4G0CE=,D)1$A):#;*0>'82#C9,(3D=-/D()BD*?9?%297-8DB1=;&7E-)=FH>#7
@r8602
AACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTG
+
/H2;)2G:3)'!,"F@,F?G7/7C;2*%82@":1D(*F%8/!6%=..,,E?)6(F2A:%BE?H?,,<$727F!G&''#$2309C")E#;+*/@#C(#:("C<+?*:69(:H1!7"$39:1'9/8,-&:3'.B6>>.3G%$A@D#<88<(?(9=#"F!FCB61,(F)"D<E-'G
@r8603
GTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTC
+
-0+6:!.B#=!>/H;+4H;4#=?AA>3'>=D=?78;5B/71*F<4B-4F<0CA)#
@r8604
TGAGGATANTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCNAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGNATGTTAACTGCCGCGTTCGCCAGGCTTGCTG
+
1%AE@2.1&;,9:"%H;4/68@2-6E988)$=&;'::'G/6-H38*F)6.?*#H:9H,(*4E9.#@+2>9+,4C5GF<G'H*":'A("+2:H:+3670<;#>+G)D<3%D,8-873DAE&'#=24828CC>1!A*%%$/)?@=<908@"G(0D=)/DG-%
@r8605
GGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACG
+
E3(%)-8"H7E@0/:2$BF/1-5%&$-?*&)0(+;EG*.F,:'#*D*63',%)6CE>,+6'5%(>$%@>F?2D):
@r8606
GGGTTGGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCNGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTCTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAA
+
->!.+@ACC+5>/23;3A>20@A/,%545>###B"%..-:0)(+,9+"=:&?)=9BG#7>2#$!G=55H78<G>;:>,)1.CB)=.(<%-G;??7EA*@3B$H&;#A69#A+3"#@F)#*AH'E(G*#3)2:/,G95C*%4C"6(!2%A<0<+205B24:99'H877!+$+%09/AH;'$B:;6E&?F%:@0*@0D=;H
@r8607
TCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATANCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTC
+
E3">(D'@1.4B#EB@10($:6D;.55<.>:0<C/**C8/===$%).=8&<#9CE:=)/5&/&/;'424'"?@7==-/%+,)'!,!+0C$##.8(B@12%;)!$#2)A$E%7
@r8608
GAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCA
+
4.<H'A+F>%!GD1.D*(+H25A/1#H'54317D=C&"('4(F20C':D>G!A3.)=F#>"G,4":!7&FD,:%.G>9:)1C.$)9E9@>A0,#D5EA4GDGA"+80(1)FF<&;*A959&!?%
@r8609
CCGACGCTGCGCCAGCGACTGTTCCNCTGCGTGAGTATCCGTGAGAACGACGCCGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGT
+
+&'3H$,.!B1:)!<1..>7'>F+E27C'0H74&:&@7ACF(H3?$A)*1B-3"'(;*:@&.%>C()4&F@-A$0>2G*27:<C?$%2"A&8$F,31H*5D=-3%6.A&)6!$1(1/;H"5@5#2;"E3&D785+E:5A;@
@r8610
GAGTATCAATGAGTTAGANTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGA
+
G)42?-)48""?"5/C9/.&G':+$!E;+%8"CG0#7'*'-073;:@6C:+6//:%&)B9&@@3'9H,,.-+>;+-,$E>?#.%+#40>!;:$)?%G$@04*)"%+1B+,;G?"EG22*D%/49'!'5*H"7B1&7.>:3&*92!'%(&(,%":;?5;92%C46#=5!>#=@70,21"D+C@F4%=@7$/95B
@r8611
TCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTC
+
A-*:BA;5HHA(BC*<D,6G1,07/=5FA:E=H<*@.;!21D**5;H5$-="(%27:58$/66G3'AA.A%)2!D134*A(BD<//1@1--=(0.8BB##&6E#)5,)
@r8612
CGCGCCCCAGGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGCTATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGNTCCAGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTGCACGCCGACGGAAACGGATGGCGCTGT
+
(;-F,.7)6&8GE7BD2)-$%8(C/>1(;@/?:E8.G(/E>(>%33<5"?/>FA>!/5D=23&996C,316+03CD5G-!'0-?4/*D?>44D%#200#94*@BG1*$+G<<H?34.2@)55F2)<G-:"9..EH"E7!@)<!-*/18*+/=!74$$B,)B@(D3F#'7-1>/B+'-0FH=?)'"$A*6=+"##,$A,<C8@';FA>F%@!=E0D3;(B>0@(.%;0B;B!=FG.3/3A?6D1C&6$G79F0#71A#0=75"
@r8613
GNATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCNCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTNATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGAT
+
*+7#6;<CH"?EG-6C%*!C9'%A.39=/?8+>06A80H>B=2F;*<"%,:4:A"355*6,D>H#'G85$?-)7D)F.A=90F;F-6)83>.H,2B!=/34)H!?'>2F%$D,68G:*2>;8:.6H$D
@r8614
CTCANTGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAG
+
)"('*+*)$!)*'+(%+)%!%!$!##(+!('!'+'#&!+*!'*+'&#)''&$$%*#)*##!%&%)''#+&!
@r8615
TGATGTCCNCCGNACNCNTNNCGTNNAACNNNGNGGNGCNCNATNTANCCAATNCNCNNCNTNNCCGTNGGCTCNNCNNNGNGNTTNCCCNA
+
"!##!"$"#"#$!!"""!$$!!$!"$$#$"#"#!$$!#"!$!!$!!!$#"!"#"#!#$$"$$#!""$##$"$"$###$"$!"#$$$#"$!"$
@r8616
GTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGGTGCCGTCCATGAATGAAGCCGTTAAACAGATTGAG
+
#/DC%=.(?"3H3"/0E>F%)9(&/1D40C35A,G)!+9!;D-*4'A2%#@D<4BA3="4GD=,EA-C;G-4";7;-,
@r8617
TCGGCCCCGTCAGGCTGACNTCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAAATGGNCCCGAAGGGCCNTGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAG
+
+#%)+$*$#&%#(*($&!#&#%%&#&*"+"!*!)$'%"#$+$$'!+#'+)%+%&)"+%&#"(+!(#$'**+%%"!%$(&'))(+'""+"*!(&%%#($+$*&*!"&#$!''+("''&%%(&%""+)((+$())!("#!$+%)"$!'$$(!+")'&$#$'
@r8618
CACGTTGTGAACATCNAATGACATATCGGTTTGTCAGCGNAGTTGTGAATTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGATAGCCAAATGGTTACACGGTATNGGAACNAAAGGATATTCAGACGCGAATGCNTATTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCG
+
"?(4)?51/4%,5-8.1!?&;D!E2*EE;A8'1>G"H=79C3A93?$%!$79<$?<38((H3B4$9)5*,*6F6$,9!C?)!7%5??8A#<2<&6#..%&5-6=BD3H-;442;*+D&H03<01'C-"1A)CDH1?>B12.1(;!=H(H26A?'1':BH:@$#2%C:0&+.+*2&3#-!9$AA$5/6<>D:89@!,-G?="-4;$:?&)9
@r8619
GCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCNCCTAAAACGAGGGATAAGACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAA
+
E=1)AG''2'#C?<7="7"734.*D03<C739B:)E=.#6D%E@:<-5*)0-H.E8!D0C9#63,D=A/=+*E==&6ED@D#)%18<B6A<=#/7>.6?AE6'A4*%E5(29.EG"-94%7%(+0"<F$"F<42-CF2G@
@r8620
TCTGTTGAATGGCTCTCCATTCCATTCCCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGNTCAGATAAAATAAATCCCCGCGAGTGCG
+
1"1-H6@(0.GCD1A1*&$!G&3H+151-!+)%$DB1CD49;D"&<!4)43H$E@?=+(75B5!6H-39F;C+,5@54#%*A#114)HF.$60+$185=?'5=6=F#10*4D)
@r8621
TGNGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACATTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCG
+
')!+$)'+*()*)#(**(%*!)*$#$)!#$%#("($%)!'"#+!+#((#*%##+##)#!!%'&&+!((#*''!&&%)+(#&)(+"+'*$)&'$*)"%&)&*!'*%)(*&'+&%%('%"#!)+%")(&%'&(+(%%#!(!+!+
@r8622
GAAGTGTTTTCGGGCCGACCACATCCGATCTNACAGATTNTTTAATCGGGAAAGGAATGTCATTAAGCAGTG
+
&"'$+%'!($)&%#"#+&+*&!(+&"#""(!+$+&#*)**#)!)!&!(&!*(*&$%#("*++*+##&&%)+%
@r8623
GTCAGACCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGNGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCC
+
2"D@0H&&'(;@FF;3C4.=$!&;/'"B#;@B"6A@3A0$)+-1G(:D.!:),H'3=F,?E(&8E:C.2@@8(?5)<"9F;'(0!<3G.=&(22($(0)1@D$A5F8B(06?"57G@2?(933)DG>,*)-,.7=H<$<74%296D8B(D.'A,.#.A36*E9H+%93&+G=4<?B.2-G+.3=.F-3G#5A+-,C&=+H-%@"<3(D=<=3)4&=&<D:261C();%10,-H8<5:G$+(CCFBG<FG1G.54*='E:-B9''&"6A4%.)%/?"#FC.=/F<?7)#>';D/@</:H3/!*>5B;<,/:6&"A0@#!"/;7A;&03
@r8624
GCAGCAATCAGGNTTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTGTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAACTGCTTACNATAACGTAAGGAATTATTACTATGTAAACNCCAGGCATGATTCTGTTGCGCATAATTACTCCTGATAATTAAT
+
%<8C'383@;B4@##2F3<2E"(<"?+F@?%CD#,<C%;&02&F!10)&/3DB3HEH@!&9&>CDG<F<,6".>-01!FDH!6@DBC4*>.G/@3%H:?>8<;>9A"(4<1=47/$.F#4%+<*-;*E=1ADG>4*+<C$;:73:1D*16B;!=@D32'06D++47!F9,<*G9?@8@A6>"8=-H2(5-/:4>@D%$:
@r8625
NANGAGNNGCGAACGGAGTATTACNGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAA
+
#$"&''$%'+&()!&**(&&&$*(""''%)!($*&$*#)"*&%+*")+(%%%!&*+$"))&+$%+#"+
@r8626
NAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAANACGTAATGAACNACAGATTCAAGTGGACGATGATAAATTCA
+
',,?7!##*.;E(F42#D%!*'>54="<./EC+C%&20$-)7B4*$/+$74A;8C$0/0,$(?-85+2"338>F<;5;:+662B0!;E9BCG;6%4
@r8627
CATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAAATCGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCT
+
2.;9;-%**+2F?H<($;A6::#?4-63D1:@)=.2)8019.A<0CGB5<B>9%&F%:#"64A"G&H(E')@/2F0=67/2(/=!<2:$H@DF@:#9##:7449>0>*;8!0,6.!&2#3C#4@"G,=*0(#!5;+F+G%23.*"H;E=:"3"?9E$>/>=*0)?-)'39#$
@r8628
CACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGT
+
D/34+G<GE*4,%$A.>3:(33!6#&A280'5H242!E9:E@88B"E=9?C'B??&,34F=.+$
@r8629
GAGGAGCTTGATGANACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTCCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAG
+
18##F0F-%98+H:26G:H#GHG$.>B(/!-7#.07F*$#%,G3128/A0E32(HC6$#CF0!193&@B'0!<D1;C.):8$1>#)B*+H9@"D(#@B!
@r8630
AGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCANACAAGNTATCGGGGAAATACCGTGGTGTGGCAA
+
4?@!27A;55+68,0;3=663CB!"5C*=9H0%>;=G6":3'*&%"9@'2/(#7->-;&,#901A(3*@6#&%".#<H
@r8631
CCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGGTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGC
+
2-(B3=0$,3?("%1)8/?57:)*HE?;#+&;&AH'H';#+*C+2F=="87-5AD/*A3;2:=5:;=/51703/+5C<C;E8=52-C5<:"(3GH<+@
@r8632
NTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGA
+
!0$:C,%:.1$!'3<:"3#7>AGF3D0C==2=5A4D--:>61F+5'*=4G/!-$D,5%D-3B8/3',)!
@r8633
AATTTGCACACAANGTATCGGGGAAATACCGTGGTGTGGCAT
+
$3">$C6-E@@7$(!A-:@B<81,,3D3E-<!B&*.9/(=,%
@r8634
TGTCATCNACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTG
+
+%*'!%%(!$*!$*())$"+'##"$()+'$%))'+#&$*$$'$%($'()&")&+((($+$()+!)&%)
@r8635
CTTTTAGCTCAGACNNTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTNNG
+
))&($&*'&&$(%'"%"#)'+)#+*%)&$((!'+)")$#$(!+(&'($#%*%%$+)+
@r8636
CTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGNTTAACGGCT
+
"*+&&+&$!*"#"+'#"'#("%&"&+&(*%$!+&+('*&$+&')&"#'(+&*%"!*($""')++#!'%$'$*(#!&+**(##+($)')&))*(*$"&*+($$*&%)&&$'(+"($+'&&""#&%$"'*$&(
@r8637
ATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCA
+
9%$A#@A9B8!/3D0F,&(%@FF"4A2.1E+2G,">.&3!@'2,A
@r8638
TACAGCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAAGGGAAA
+
=+)'@"3HG+>$G41*(<F5B*<G5$A>+%D!/F727+/%42'4&!'1AF:?;34.E==>$
@r8639
GTCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATANCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGAGATCAACCCGGAGCTTGGACAGCCAAATGGTTANACGGTCTGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATT
+
*%#+$""#+('!%&"!+!"&"&&%()+%"&&"&(')&#+#'&&%)&"(*+#("*!&)!(#+&$&)#))*'*+*('*&&&%*"(#)$+##&"#$'"(!)(#$!&&#)$%%+"&!#+#!!'%&!*!+*%+*$&#(%+)$'%""$+*!#&")""$+*!"&+%))+!*'+((#%$(')&&#&"&)!!#'$#")+%&'#&+&&(%(!')*+##*(!'&%!#'%%#+$+%%*%("''"+&(%"%*$*%&)##$%'*%"&&%)%'(+$&*%)()%%*
@r8640
CACGCCACGCGGGATGAACCNTTTGCATACATTCNATCAATTGTTATCTAAGGAAANACTTACATAAGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGC
+
*)1H!&FA=(%7A<E1>#??33CBC2B5;-07$#'545C;:3F7DCDHC>21@02015+AD4*<E.%)HG0.%HB'G&;2;A/@,H>1EH!'"7&*&,A$?E;$B!0D'6>D=H8?@@=@G?8#FGB1&0
@r8641
AAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGCATCGGTAA
+
D-7/5F'H&5/1*?!')$%,6=4D:65+.1?57GE+/555/*B2/!=44#6A.
@r8642
NCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATT
+
#)+*90-:!@E1!@<A=69F.1&.E8#$:-DBF1+F@%.::92D%5*8BGA/@7-B',",F?67#,5CAA3)'H#=;!4*6.(-=E(
@r8643
NTANACCNTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTAATGNGCGCAAGAATCAGCGAACATGGTACAGCAAGCCTGGCGAACGCGGCAGCTAACATGCAGTGGACGCCAGNAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGGTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCANTAAATATCCTCAATAGGGAATAA
+
"(*$)()+"&+!%)'(&&$(*#&'!(!)"##*++&"#')!*(%"(()&&&#'(!$()&%)"!#"%+&(+#)%"(!&$$&"''*#%+())!')'+'!%&&'"*"!*!&$+)()$'$!"+'#"(&'#!+($$+$#)!+(+**))#*'&!!$&%#+%!%++'%**')*#%$%)!!'&(*&&&+!"%'%"#&'&+*#!($%))#'%)%$*(+$'!'$%)&+#$)'$!+!(*+#)'("&!#$#$$'(!"'*&!)'&"$)(%%
@r8644
TTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTG
+
B&'$H&?#0-23980?DH6D/)"(.8<.";=D'.;'!'.!;G*C):"B*:9.G6;+DB#9
@r8645
GCAGTTTTACCACTTTCCTGACAGTGATAGACCGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAA
+
7;><FF?>F5"@:7.9*(=!<8'').=6:&E75)F5*?;5F))>(H-.>*@@!E-:C&0;@3D+#-'./B'7+7>4H)0;>)0$0;;/=B7?.(9
@r8646
GTTTCTGTTGGCACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGNTTTTGTG
+
-&E(4'AHA!.5+CD>A8DA30&:"&=>2@;D*=-.<1;@C?&F%*;,".&,*)?CB7;C2,95>2$/)-5(!@6#!:->C%&E1';&*EG6(1+G423"*:H?"@4(0*(=F/&4A1F&!.7.A>5'>&6<:D*(36):.(2>2#.F
@r8647
CCTCACCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAATCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACG
+
*18'*?%@D64<26+#>A45GCH1$#*"'0%:@-5?)D3:GH$><GH4"CBA0=BH6#/;!0?C>'C218A-'H.<G&-E8-2H/9E:-0$<(&)!5?%CBH<F+0@41.,=
@r8648
AGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAAGCCACAGGGTGGTCCCGGCGCCTTTCACCGGCATT
+
:-6#,=?F%0(H/@1C,52F'9H,/;1,#1"CA8B7CE0$E+A=9&&"&9<&C.63))A5/D*=<3,>,:/$>F36#)!;HG@61?1F*;"-.;9;F5#,47G0F#?E.;*-(;
@r8649
GNNATCNTCNATNNCAANNCGACGCGAGCCTATCCANTCGCAGTNCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCAC
+
!'!##%'%'!'%("&!%'!#%*)$$+('#+$$$+&*&*$#'&&**+'!($&#((*+!%!+')$'%(*$$''$)#&)'#'(!#!!%(&+#%#"*'&'&*!*''&()'*'&)(+'#)"#++*++""(#!!+&%(%)')
@r8650
TCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCA
+
H#6!A8>/(H7D7%%H*@%?3<'@;%G@,C@7.(3+8(9,.&'D(8%$4?6&7=$%96:A'E5@H=9.9,8A4!E8"%6=!"=C<:;7A'C7=C$GD*?BG#4$##%G"B57<@,BC(
@r8651
NNNTATAGNNNAGNGNNNAGNNNGTTTCAGNCNNNNNGGTNNANNNGNGNNTGGCTANGAAGGNTNGTGANNGCTCCNNTNCNTNGNTNCCNTNTNTNGANNCNCGNNNTANNGTNCNNNAGTGNCCNTNNCCATTNNAAGGAGNNNNNNTGNNCNGNANNANGGNNNNCNNCNNANCGNCNGGNNNAANATCNCCTNGNANTCNACNANNNGNNGNNCNCTA
+
"!!#"""$"#!#!"!"!!#"!##$#""$$""$$##!$#!""$#!""#"""$!!!"$!!$"$""!$$"!#!#$"$$!#!!$$#"!#$#$$""!!""!""$!!####$""""###"$#$$"$"$$""$"$"!!$!!!!!$#$!!!!"!"""#$"####$"!"!$##""!"$"!#$"!$#$#!$!"#!"!$##$"!$#!$!"$$!"""##"!$##!!#!!!!!"!$
@r8652
TCAAGAGCGATGTTAATTTNTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCNGTTCTTC
+
5#'5$?AGG!-/%&H?:/#2C>$'!09$-/*;78#)"&7+?")9%4G$G<4($*AE;5*5(,49$<)E1.#F7>>*3C"6"
@r8653
TATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGA
+
BH#9$C(9:&(GF<E9"/:;$>+1%&;=!%F9:BE7@-0>*9H49-G;4:?D??#>>C-$6'D(E=2
@r8654
TNAAGNCTCCCGACCCGGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCT
+
%"'"%&++)&#&&'#!)!%$#'$'!("*'$)&"#!*)**)#+')(&!+$'"%%'*'+*)%+*'"*#")+!&+%""!""$"*"%#)!(
@r8655
ACAACGAAAAAGACCTGCTTATCTCGGNGGGCGANTTGGTTGATCGTGGTNNAGAGAACGTTGAATGCCTGGAATTAATCACATTNCCC
+
5=#(1"@7$/=B1D/G$*!A!/40$:D@,GC0<-:6BD&/9@+A2-->-->#<)C==8A%<C&A=E<$>%C(#EF(&HE8*-0$H7&=D
@r8656
CACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCAC
+
15?H21E=28!)##-2,=;B>*3*F2F8HG)B%78*09DE
@r8657
ATNACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGNAATAACCGNCACGGGNAGACTTCACCACATTCACCTCACGGATNTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCNAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCT
+
**&$"++%$&*(+)#!"(%+*(((*+*!&##%')$*%'!#(*!"#&%#'*$"&%!)*%)*%*&*)!&"+&''!!&%"(($#)%&"&'#$+)*#+"%'+%(!*+))"$+$)&'*#%"#(!#)(#&"''!&&%+)#('!!""'!$%)!&'!#"$+*&(+$$'"+&!%+"$)##"!')"&+"(!$""+"##$%'#"$$+!!&!'+!*("&!**(&$+'%()%&)$#&#&#%)"##)#("+((%"&++*$(*)
@r8658
NAATTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTG
+
-H$4&*B:8E'.H?G"-"@;-%B571&@12*GH!1F2!F!/@?G*F%3'14>5
@r8659
GATGCGGTGAACTTCGTCAACGTAAACNGTTACGCCGATCCGGAGCAGGAGGT
+
EC.D(4.E<F#&%B#49)0/7"*+/!HD9;H#3B5,7;$7B+>D.E-!.&F,9
@r8660
TATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATAGCTTGATACTGTG
+
*&+"!&('%')"%($")'&!)#"!'"()!(#%(&)#)%%$!%!&'!%#$(+!')))'"*!$!)&%#)'(##+)%)+$+&)%)&$"%'*'&#$+$#%#%%+*)%'+%)%!"*")$")#&(!$*(!%")*&%#)(#"##'**$+)*#!"$*('#**
@r8661
GCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGNCGCGCATCTGCCTTTACGGGG
+
55D&?6;B@&$4,8!=7.1'.!.%/ED9&#3'=4:=0#&=4:G";8:<E1B%E$+3/5@8?
@r8662
GATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTNCTGCACTCGCAACGCTGGCTNG
+
8%4FC/G/-6?G<7+73'<%)692B1A-D7756!$&%%A"38);D)/#<7,;G,4!4@&@+.:7>H".>2(,>!>0B=6/H?G="F2D95(1,D-"%>5;5*6:#4=$D2-"D?C;D7/5>-D>)/'A=;=H1
@r8663
GTCNTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCA
+
#')"+!'+%$'!*(%"%!"")%&*$"$$"&*"*&''++('++''*#+**"&)(*+'%$")+'"
@r8664
NAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCC
+
'$AH$/;B%A$75B0"7?=>'::<8B35B;>$9811!77849@
@r8665
ATATCTGCACAACAGGTAANAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTC
+
C:F8;-FCE-FC$6)-2/7(?0F<C;9'4;D#76);)=!/HHC4!:"D)($D%EH?@73F/:$H!G==%)$1
@r8666
ATTTTATGGGCAAGGCTTCAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCT
+
&"&"&+'+#!"$!(#%#"!')#+*+''$!$)*!(+*)()*((&!&)*+)$#*!'+$!'*%&#'&)(#'+#)(()*"$)"&#&%!'*)(#$*'+**(+#(&&("#'#&#&(&!!#!(++++"%(*$(
@r8667
CGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGG
+
65),2'&(<<&(C2+!GB;)C0&*7#E#12!"A5*=F8*;&)H90;A@A)"4FF6$G41&@AA-.#A*&"?4B)?-,-@D6,H$!
@r8668
TCATACGGATAGTCCTGGTATNGTNCCATCACANCCTGAGGATGCTCTTCGATTCAAAT
+
?.&+@24):?*B!*."7-!..("6:*1"C1)$"7CGBA/>73?%@6(#D2=(?-/=(EF
@r8669
AGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCANCATTC
+
3F>*B)5?#88F4758GA!.EG==?(57-0'45EB?4=4:A38@!4>3:.5+%;)2A5E?*0<&&7/C=,8<'.C&$>/D
@r8670
TCATCTACATAAACNCCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCANTGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGNATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGC
+
3>5H-(-&D==27*,:"AD669A<=G.(;:A1)4BF'7>5>-C0),">%*9+*=">F6!=F-7(=)?A*DD9G;D;<?H//50-A./!,,D47=+1+&2'9&40G<65*.:>>#6%"0<?7/B3C:1?#.:2CD'(C#8($E;,@64F>H-G6793H0)@18<=%.H>)>",D*9H%%D%%.GG'7!7,:2%3:!C3;'7<14F?5*%+0-93'=210@:%0;+64!-1#5;"?5).,37C<EA.'@+(D56'8")!(5)80,:/?.<,2*1&E/4H&G7%5(11H*4<5:,-(AE+2/+C5?,8@%)+FD@-FA>-7$0C.(G:1'6:"!DDG6?,A=GB+&D$#;.@(,.H@30(<#)'74:EAG7$06F>&$<:C8)5#G6:H541G4<3
@r8671
GCCGGAGCNACAGACCGCCGTTGAATGGGCGGATGCTAATTANTATCTCCCGAACGAATCCGCATAACCAGGAAGGGCGCTGGGAAACACTGCCCTTTC
+
$6)$5'F!:-;>.<!7-?B6/E/H@0="))7C2424G<3'.4',-??8931)82"#@+3#HG4B/:,,/!:&21=&6>$#2.(!#:HH71F#H9?A'!"
@r8672
TGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGTAGCCTGAA
+
37!5&:*:/84%$.ECG7*;AC/@$33/!>?"02>)4E;C6BE@>BD5,CG
@r8673
ATTTGTATCTTCATATAAAATCGATGGAAAAACTTTTCTCTTTACCAA
+
E!67,*41A83#!=+;07#8=B9GA8B:?B8#5;0:*!:-&<E.&319
@r8674
AGCNCCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCT
+
.$9CC*)*/7;$;"C1@)$-A'(?$&$*HE&%B<H#!><7+A=5!F)?7)/@
@r8675
ATTCTCTGGAGTNCGACAGGTTTGATGACACAAAATNANCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATGTAAGTAGCTGATTCATAGTGACTGCATATGT
+
!+!'(#'+((!*$&'%(#%+$$)+#)*'&*+(&#"*)$&*%')(++#&'&#($**+$+'%#*$#")%!(!&!&&+'#)#+**(''''(()#$+%'$*&*&*#&"!")%#+*")%("#")*$$%%*&+'
@r8676
CATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTNTTTCTGNAGACGT
+
+/9"'52,217';?%7/)/@$13F$3@&:>.359;$'&(A0A38G)=E(>,?#$#2E>'"12F>>'B$$E9@B.6D;8B33#BE'02$F82)2A.=;
@r8677
TTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTNCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGNTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTNAC
+
0,;/*E,7'!D)4C+H12%?/6@?9GG*%5!)1%5:F."1?)4'?33?*78F95>./?!#%6A@);$9+C'.4;-8C#"8/70:+$7.::8C'A/@E2$#;@;-BG:<)5@<?E6F-/G*)BG6A(9::7G?6
@r8678
ACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGAAGAAGGCTTACGAACGGGTGCAGACGCCGCTGGAGAAATATACCGCCCG
+
HD=B"G%>G<'<C4&1+6A:9!("(*C9$4.<7=0C+2'4F36H4C/.H#5;.)"B=:HC6!;E:7*!B;2@>A<?(!GE/&(@)"
@r8679
CCNGNTGACTNGNNTTTTGGGTTTAGCGTGACAAGTTTGCGANGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACNATGATTNC
+
((#'$'*(#%**'%'+*#!*'"!**'#&)#&")*!'$#!'(#(#"("$&*&"&"#)!$&$+&#*#))"$%+$'*&#!()+&*#"%&$'%(%$+$(&)&*!&"#
@r8680
TAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAANAGGACTTAAAAAGGTTGTNAATGTTAAATTCTCAA
+
;%'H'.D"@06.<!2H6"6D!1&-+%.<3$./:(F%=?BC/26,2'<!H-%G$9"B9,+3A#1)#)26):5@83')/=./;,;8#699(F
@r8681
GACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTA
+
#>;2%4+@+2(1((F$EC,!(1=A53#8>E18B/*!56EH!2+0-A'49;<3*G00CA945A:C:"!"#E91D,+<#D2**$D
@r8682
GCANTCNAATGNCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGNCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCG
+
($'$($#)$)#+#"%"()"'+%'$&#&"#'!'"*(&)$)'$*+#%%+$+$(''($#+"&($+$'%%$&$$(%$)$&"*#')")+)&&"#'')$("%"#)(%!!'"""&"%*""'+!)'+&))!(!&*((&(#$)$**$"+(#!$
@r8683
TCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGC
+
8G&/@'=3>8-@';2,,+>$4#G'>'27<;$'7GDG+>->+,861#:&1!,.@?-GC';*#,$8+G$B!/9!C'/#:6AC!H")'=G"B)6@&AF"5,=(.@=A=D(+3+%/55+H-/)122@!2083%,3*A@<A79<,(E820#G!"3(D+&<1H07#;-%A8@C$E'..:8G
@r8684
NGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCC
+
%.%C60*A.>B40'>FD01(5%!)+C@53D=B$&$>G.-&D%14
@r8685
GGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTATGCCGGATGAAAGCGGTTCGCGACGAGTAGANGCAATTATGGTTTCTCCGCC
+
B1D%G+=;+"D8.7?8AD(/7F7")>C?&3G1)@.0H6<.(#@-=-&,H-'69B$E5G-6AC+""@2/C6A"%E9B?=HG9/:&2)3&./D5GG'"+CEG%5#ADGB<=,H1>E!E"'?3
@r8686
AAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAA
+
E<"&6&@!!+.D5-&'H,@+3"D(#"7D??/7'=%BB'-%-
@r8687
TNGGGNCGNNACTACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTNTACCCGCCGGAATGNTGCAGAAATGTCNATATCCCGTATCTGCTGGAGATAC
+
&'%)#&#&!%%"$*+)'&!'*'*!+*'#'+*""&&('#+%&+%&+)!'!+%"%#$*++)&#!%'$!$*&#&+$)&*#&+)#(+&%+%*##+'!"!(+"!(%+!!#"!#'*$)"#
@r8688
CGAAAGAAAAACCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCAAAGGCCATGCTGGC
+
("9!$74!&//7-0-0.<=4&?="D"/5C<-.G3?/'1$'<$!>/3"=",#5$'6)7"7
@r8689
TAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTT
+
575?.%#3;-?,"G.)?.4?#'#0,!/CG(+7G(.+0<6$<1*"-"=<-0:(8E=0#%B
@r8690
GCGNGGGGTCACGCNTGGTTTCTCAGGAGATNAGCACGGCAGACGCAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACC
+
))#"+%+$'+$)'%$$'$%(&%$!%*##((*($!%)#$+"&#(!%'"%%&'"$#"&&%((!!&!#+*#*$(#+""%(''+"')##'&$+"'%**!')+('!)(!&&
@r8691
CTNCAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGG
+
3$=2$3@&4:EH7.220E0D2'6AE103>72',5'?=777A$$2$7<:
@r8692
ANACNATGCCCCGCGTATGAAGCGTGAAGGCCTGCATNATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATCGACGAGGCACTGGCTGAAATGGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACCATAATATCCGGGTAGGCGCAATCACTTT
+
#'('$)$&)+!'&+**##%$&!&*%%$%)+'(#!#$('*"(!+)&##'%!)#$$)%%"!()%''%*&'&(')#*!*+##$"*+!($!+*%'%$#)!*"!*+"%(*#)$'(#$'+""'&%'+"+++&!'%&!*"!%%"%*('!*+()'*+!*$*$'*+**+!%'*$&&'+#&"#*#&(')#**#$*!%'$'+"!*!)%++)(!$
@r8693
CCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCGCGAAAAAACATGGGTTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGNCCAGCATGCCACGTAAGCGAAACGAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAG
+
<<?,<!>6(9+";*2CAD<,0,%62*<13F?%'0-7/:%E';C-8AB&>A:E@,)&'.*41<D92?-?!H.E*F:4!C=C7-%/H?A=/B<#-6)G=AA6G>7=+0@&B@#-"72?24-.!(H.6:72>F>A>4/?@C--1D*=3%*5%D-/21AC)$B5C#4H?'BG8+3<#1?23@;?G1GE"GC%$&F+<@C4DF$H!<7B,<;!94*B2=-+**>),F).A='5>!C6-G**1F#B
@r8694
TAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCANCGCGAA
+
1!,/B$C:-/=B1H5":</$E@$=H@0)4(*A255G>&42A/H(+
@r8695
TTCTCTGAGCCCACCGTGGTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGNCGTCTTTCAGGACTCCTGAAAT
+
;4$.2--,87+63C5C&!?1(@"A?,/>F517!>'14D4$"E?<7,20;?@60AF-76E@2BH/?FE"3!EF:?8"7&+-6;("*#0>2%2H"07"2586$&@GAC<E;A6B<
@r8696
ACTCACTTCTAAGTGACGGCNGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCN
+
=:>@9.*6<*G=@=$A'96G!&H!9DF9<7<@/3%4@>09B>.0A,);$(5+*42"/"#@<#(@-022&:(=E0'=D(4?BH0
@r8697
GGGGCCAAGTCAGGTGGCGTATTCCAGATTCTCCTGGGCGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGANCCACCCTTGCAGCATGGGGGGCAGCCATT
+
$+!!%!%&$*'(#*#&(+%((+'*('('!)(#'"#+)&+!!&'+"+)"'*+)!"!*"+'!''")'#)+&%$$!%*+*$)%$")%"+%(+(%)(+!+&'!+'+%$*
@r8698
GGNCGGCAATACACACATTACGCATCGTTCACCTCTCACNGNTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCNCTGGCAAACGTATACGGCGGAATA
+
!"+!%!#!!'$+*&")#)*$)+&*"%!+$&!)!&')(')!'&#(%($"%$%+"+*(#&"!("&*&#""!*)#&*''#'%$#%&&))'#$'!(%%#$"$&('+&+%'#("$$&*'&'#+)%&)"&$##&$&(&(%%+($+#'#$#((*++*'*$*)#%!(""+%$%
@r8699
NTNTNGCNGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGNGTANTTCCCTCGCCCGA
+
#(#&'$%+&%*+$)#"!$)'!#+%!%(%*('+!*')+)"#%')!('*$'*$$(""!'(%%+(
@r8700
CTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTAC
+
E?@9E&'.?+A.*6>?0F1<GH,B5/BD9!!;8&6,')B73!A?6")80D
@r8701
NNTNCGCNGAGGCTACNCGNACCTGATGNANAAACTGGATACGATTGGA
+
$!$%$"$!$$*(%'*('%'+&'"%')&*$!"+"%&'')#('#$)+(*#%
@r8702
CATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTT
+
10E)D1#%@B,>@34)/D(F1!;%C)(#'B.D:0(?E4;+@C1&5?#>&43"D$#:7#+*)@;6;<C+8*F.+C-A6204+>!";5E52
@r8703
NANACGACGGAAACCACAAACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCAGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTACCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTANTTNCAGATAACCGCCACGCC
+
#$#+$#!)$(#*&$%('&$%')#'&$&!"*%%*&*%'++&$*!(&+"$)#*"$)%(!$%(#$$($***!(+!*'%#*+&%%'%'($!"*"*$"+&()*"*)(+%%$'"!%'(+)&+*$&&%%#!'#"!(*%*#"('"+&'!$!"(+##*("+"#%"&%'%'+)&%%$"(!"))($*"+$''&)!'
@r8704
NGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGATCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATG
+
$C8(7$<FE.G@*/*F';*DEH3*@0B:)"%+B"<"+<>2A92.E&,G,F.8CC6&?H5@$=$!<A;G-2@/3D<8:;43!:D4$E4<<B89/EA-574,?-F6(;&DD<2*C=-H@(.74E$1G+B#B'D,+%.B?:@A3BE;0*><EFCE4+*$7)D=<B>=H9<FD%48B8-
@r8705
GGGNNNAAGNNTTCAACGCTANCTTTGAGAANTTTTGCAAGCAATGCGGCGTTAAAAGAATTTAATGCATTGATGCCATTNAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTTCTTTAAGGCGACGTGNGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCA
+
(()$(#&&"(%')+!%+"**!*!+#!#(%+%#(%"')"$&(&(%*)+&&!)*((#&&'&&"($%'!('+''+++#%$&*%&#%)*%&''*)*!%!$!!$"%$!#!+++*(""!$!&!++&'+%!%+)%)!++$+"''()'+%&)!*!"($'!"+(#))##(+)&)+**!+*(#"'+&)+#$%!$&"#$$$)&)''+%*!)&'!)%"+$!!)'+*%$"!$!#''$(#"#)+)$&)&**"&*#*!)(+%"$*)
@r8706
GANAGAGCCACTGATGAGGGGAACCACCAAAGANGATGTTATGCATGTGCATTTCATCGGCCGAACAACNGTGAGGGTAGAAGCCAAGCTACCTGTATTTGGCGATATANTAAAGGTCTTAGGGGCAACAGATATTGANGGNGAGCTTTTTGAC
+
E%5C:#?.%!.1$CDD<DF6"3EE"&05>D>03=(?;2>8.A@5?'=)E1!>2):*5B'$!56,?")1A37#42C+$"3+#:0<*?2D4##0D*E12'9)?H:"#!%8B"3>@B<AB:%8)#@%/D4&305#E$!:GE-F'#=>;)F#)(!E>?
@r8707
AGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGC
+
#88:65%CC!&*+2$EAG.9&,."C$-23,<!9A4;*)8'G7<.B'HD)+:9B6!93C&F3:
@r8708
TACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCNCTATGCATCGATCATTT
+
-%"$.4-H4/39G'7-H,D%43$?..=5A0E+6()E"F'61!+:;B7($4'%:530D'FC5&@;:!G,;7GHCB)-<-=(;/'6@2$*4C5/G"?@<#C=)
@r8709
CTTNTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGNCATTCCCTGTTNCTGCCAGTTCTGAATGGTACGGA
+
C1/23!9ADD46?B&**@!-8+(8=$$!<E$,4$7GA'&A+55@@92"9=>-9-2-4$!6&'3$G4$F)//;>%H.2;H3C0:?3<720%DE))HA/.!5-2>%>124%5")!'=#<(1C8GF=E%>C*)F3*;.B.
@r8710
NCACGGTGGGCTCAGAGAATCCGGATGATGCCGGGCGTTACAGCATGGATGTGGAGTACGGT
+
"A="G;/C1$21$>#$DC7&GFH.9C&*B$D!><3>5<%9(DC?$$?A2/10E"A4>F!9(!
@r8711
CCCACANGAACTGATCACCACTCTTCGCCAGACGGCATTTAAANGTGATGCCAGCGATGCGCAGTTCNTCGCATTACTGNTCGTTGCNAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCA
+
+"%&()&"&($&('&"+&%'(&%*%)!*)+("'+)&)$*%!&+)((+!('&''$+(%)")++""%*##%+&)'$#"(*$#%'$"%+%&*$+$"!+(('"*()!&&%&%++++"!)#$%$%*%('#*#"'&''))&#$'$!#)(!
@r8712
TNCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATANGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTT
+
(#45?=.,;FFF5D'63--'9B+(91:*0,EE"-;:=:;1C+-,:(@#*=*'5G+0/;9F/0?5:>0&%7@D.C)BDBG:=&HF?63!8"H*8DH4*"F*--A&#;EG>,>)--&"2B;/C7<"7;;;5D12D85F=/%2-A/?=A7=H0->@00$3F1;)F3A6=943:3;A/(B11';=3#9?@/E#FH:0<%*+=75..$!DB
@r8713
NCAACNCCNGACNGCCCCATCCCCATCTTNTCTGCGACAGATTCC
+
#)%"%!()++%("%(%"#*)#(*&#&""&+*"!'"#"%"#&&'"%
@r8714
CGGAACATCCGTTTNGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGG
+
!($+''('!"'*!&+!#$!$"$)%)"&($(%!"%##%&("#*(($&!%$%()!)$!#%)'$+#)#"!#
@r8715
TATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAA
+
>'0279*8,;@/8&(;18*40/83<;@2$09C6?8=%>$30
@r8716
ACGTCGGCNACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCG
+
:D.!$-H7:A"5&9?&".6E$#/D(D;B!:!;H:$-67E8?,GB!.B/8F-+B532D0A?AA5<99/%7971-.>)ADD.CFC=-0,3&FB)!/18-4C*(!B-%('6515H=CD*9D4#5%<B#76-/0<=?;6.929
@r8717
CATTGGATGTTCACAACCTGTATCCATGANAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCG
+
/3.62-6-7B49&)B#/(<G$*"/C94D2"%<7!B3&1&9.:;,:/8G/@1)-E5&0.FC2=A%G5=!CCG643=-4*$<F--F-9,(<7E#4C-,)>-1&)501=
@r8718
NGCGGCAACCGAGCGTTCTGAGAGACAAATCCAGATGGAG
+
/5""*"2F**?/:3B7619%8"%<3.@&29C=0=&6>!.A
@r8719
AGTNATATTTTAACCGCTNGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCAC
+
(#)$(++"('#%!#)#!)+(&&+'#&"(((""#$)"&+%+%#$!$(())%%#)"()!*&'!"$""+$)#&!##"#+!(""!'&!+!!')$(''("!++&$!$$+*)(!+%)&+##&$'$
@r8720
TTCTGTCCATTGGTTTATTCCACCTATAGGTTTTACGCAGAATGGCAAGC
+
&&7:HD>(";&FG7/=+$@3E,H=E3&B1F,+5'."B*0?",()E9.;"#
@r8721
CCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCACAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCNCCCACGC
+
#+*&"&!$%*"#"!"'!'!%%$#*)++#%++'#%*$)$'+!(!&&)!*)%(+$%#"+))*)*#)!##%#%*&()""**#!+*'+(''#"!#'%)%#$$$%+)$&+")#!#(+))&#+'!$"#)""&'))&*%"$"+&%+$*+!)((($!)$%*''(*)*%&&&(&(
@r8722
CCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCNCGGGTATCGCCTTCAT
+
44.@5$=98=?>21C46460.&9HF1B/<:,B(E<:.BD-HD$G/6/H1%%A1D/CFH6H!=
@r8723
GCTGAACGCCAGCGGTTTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAANGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTTAAANAGAACTTCCTGCCGGACAACACGATGGTGNTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCA
+
<(B9?55.(B65-+3$)19%4E=3>-D+2-8>,85?>B9CD=H.G+%.6/E(;:5<4&>9:'3,%0,FA/6HBA'FA)*1'DH#-GF48H2G"A(9'!(,-?65G0790!#<BF*@3G&#.B';8';49+:C",/%>C-*=B+6>D><;4.*%F*@,)$$B8A3#1*5?**"<1(1!%""(%298F42#80,&(:+<FF54G2-%BA:#E$:6>)1--2H$H''/=(7+29*20A48EC?,(;D*A,+4"AF6)F'%&F'7';!?/EH(H>94/"@&%88F+4E@'+,&E+(:G+@51C
@r8724
GAGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGACACAAAAACGGGGTTTACCTTACCGAAATCGGTANG
+
FG-95-22-9"E/;D=H"3E+6%H2.AHF?!G%'+(5C2620;F%+&G(CGA@B(5;=B8:(=B1-51759AF07#AAB:8,;?-5*7.GF6&))<6*AB59EG#:4C$.183A">4G&CF23&$(C5.?)<BD5:)"0A'@62=+0?4:"72#00+<(F&47A
@r8725
CTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGG
+
8%$#(HBB*6='/<<,6)A901,=6"H<-#./(6HD4D2@.#,9
@r8726
CTCCGGCTCCGAGACGGTGCNGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGT
+
=?AC"!-/!"@7'%DH38/D5C1AF4<E"444?CG>=$'>D7B,9>=9.-6)F$&C+D+#!'59!>F:17H8"C0!/<B33/&C/=8?H5==5F>:9?8(#07.C6*8D"(+"/9B0;+
@r8727
ATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGNTTTGCTGGTATCTATGACAAGGATGAA
+
9<=")B"<6(B8$D8D"(#>@#"+';FH+E!426(,6F;::'2'"1!+52;*/E4@E0::),&#@D8C-,,"=39
@r8728
GATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGT
+
!.8$6:G"3<-7E141H+B&">F+&6G@+1>).'D-"*,"D!0>,'.=+%=(8!7*
@r8729
TTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGAT
+
G.>$G>>1;3:B01,,:@:..8*A;9!B8">?A@B3=;A$>$A-E15=?68600&0A
@r8730
ANATGTTNTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAANAATTAATGTTTGAATGTGATAACCGTCNTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCNACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTAGCAGTTTTAGACGCTCTTTAAAATCTTCAGGAATTATTTTATTGTCATATTGTATNATGCTAAATGACAATNTGCTTATGGAGTAATCTTTTAATTTAGGT
+
$!&)#%"+&&$%)&#%(+(#)*)!+"'*(#!%$)&("&+&&+!)$"!%'"*&+*)""'*##'()&!!+*!"&$#&!%*%#$++#'%"#*&$+&!)*)*"'""$$&++$#!+)&)'!&#!('+%)!$())++$'!"'%!'++%"*#+)!*"$$"(((+)!"%*)%+'#*"')&)+$!*)'#'#*)#&!!#*+($%)*#$+**)!$'#!!&*)+"#+!)+#$)''!(!'*''+#()+!*$(#'#!!)**!!*"$"$("
@r8731
CAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCNGCAATCGCGACCAGTACAAAAGCGGTGTTCGCATTCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTT
+
15;;+:E,*!<0,4.0*):.20DD=9B"&D?,/E2+9G7#:,"+'A3.%+)+25":6/"+H5$$.5"<'$$%81($7?A#),GFADC"/H8C:D%#'FA202AH+!E5"E10&"!B001(:&C-1E2>GB>./21G;&#7D;6<01=1*,0A=%G'*)&>"E<;:&B@36'4!:2G80?":#:($A,FA6:(8H.+/
@r8732
GAAGAGCAGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGT
+
4H-+<?*&E$E2'F=+$B''<<6<.*0G($H)06G5F2?235F3&<C;
@r8733
TTTGAGAATTTTTGCAAGCAATGCGACGTTATAAGCATTTAATGCATTGATNCCATTAAATAAAGCACCAACGCCTGNCTGNCCCATCCCCATCTTGTCTGCGACAGATTCCT
+
+!+#&"+&++*'*&"()&&&'%(*%&&**($)())+'!""$#&%'()+)''%"+*&%'&%(++"!%")#'+$!*#$''+!'#!'"&&''%#+$)$&'+$%*'#$&"$&)"%+!
@r8734
AATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTG
+
E)1;7G*7C"5-*?"D%#$6**$$&=*6:20C,09B0H3&.1D$%()#6;D..E?55.&6?=D;H*""9!!:#?)H74#A),B162HC;BD@E!);6'9=.&D:E)#G?8,C5%@)G=("F,96$<(>D-?;3*&@
@r8735
AGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGC
+
<G7=>#$+$)6B,7"!<,7D)+5A;(494G54#/.)/'!@C1<D;2G7:-61:+#,%.D*CC(*,(>><*G>
@r8736
AAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGAACCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGG
+
33H8)=$3=$0F>G'G:*H0,%==B!6,FFAH/C@6B603A:G+-/;A*&()7)'AAF"&BH;#9+C82H0&8;)-0H:'@7#$A7<17>).@C06A.)@<9?>1H'(>506C;--@@32://C1
@r8737
GTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCG
+
1115(D'FE5,+%*.0D4D>GFC.2#C*)8A9><";2!E<$2G#&2
@r8738
TAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCAGGGATTCTGTCGACCNAC
+
7"480F&1'2G7=!F.!'-FF19&>*;FA5E2GD*)90F7;17G672@,EH#%'?&24/6"*+A5.',:969#5*D3@
@r8739
NNTNNNNNATNANNGGNNATCNANANNTCNNTGNNGTACNTTNNCANAAAGNANCNANNANGTNTGGANTG
+
#!$""!$#$#"$#!!!!!$"$$#"#!!"$$#!!!$#!"##$$!#!$!$#"!$"#$""!$#$"#!"##"!!#
@r8740
AACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACCTTGCATTTAACTATATTGTGAGGCTTGNATAATGGCAT
+
DDHH.3C:AF57E:7A9'-4'&""=:2>H:-(;>98&D=#02-*=*G=0-)'+B/!6'"'30!?&0&:'FB-,F>
@r8741
GGCGGCACGGAGCNGCGCATCACTTGTAATGCGTACCTGAC
+
?29'B.7!:D/9;@-?9<B$9.G2/"0D,?"6-!:@23"CF
@r8742
NAAGNNGTTAGNGGATGNTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGG
+
#'&*"%%'&&&)'$#')#+)%*)&(%*)"!(&$$+&&'+#+$*(("*%#%!(("*&('(!
@r8743
GTCTTAACTCTTCATATTTAGAAATGAGCCTGATGAGTTCCATATT
+
.,G<"$1,&74#3#<"4!C>2:97,GA)?661A@B(+*-?(,FH@,
@r8744
ANNAACGTCNTCCTGCGNAGAAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCT
+
$"'(*#'"(!"#'(*)$'(%*&+%%&#'#!)$&!"(%!+("'!%$&)&&#(!*!+"!'+&%*'"+"$
@r8745
NCNCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGCGTGGAAAGCGAN
+
#%()((+($#'$('&'#"&$#'!)+)!%(%#+*)(%$&('*)$!)+)'$(''#$)*'"*+!('+(*('$+
@r8746
GCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGAT
+
"7,E97@+.?#:8C17$"B+7(!&.1+<&AD.F'HE0369;;!6?'+2>#)@*$)4-8!($3@$/D)2E.!!.07(0.4<?*B1!3D#%;%&D*::C-,H@12C;@'87%(-8C4//A(B@$)(:<GA,6G1)&"#,"6*"</@;,E<'::<0@):E6.<?%$H92
@r8747
TNTCNGATCCTTAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCC
+
(!%"!*()*(!&+")!!$%)#))*!)'"(""*"$$&+($"%#)!$""#$+&(*
@r8748
ACGCTGGCNTGCATTTTCCCGTNTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCNACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGNTC
+
(*&$'))('++&"+"$&%+#+&'"!&%("%"*!#"&%!!'&&'**$*)(((*%)*"*"#)(%$$)*('$$'&'*)&##$%""$!)%(&!$'!$()%''**'!%''#%$*%(&&)##+'%*)('&&$"++((+'**$##*%!&#'&$%++!&!*)"***&#)+)**&!+("+%)!(+)("""'*%)(#%*%(#"&%)%"*&($&"+"!)%&+!(("#*+#")'((#*)&+"&'))+%"'+%%$+"!
@r8749
ATCGATGGTCTGAAAGAAGTTCAGGNAGCGGTGAAGCTGNTAGA
+
DDC8AD0G.<(6+7"5<8A2!&;:4F!8DEA(A&--&#61:@%'
@r8750
CCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGCC
+
3%2<;832<*$>AC%&>'(1(G*-<;;3'96=:(G17EB@23E-)E=4?+>*;?#3#HHD=C+/'(%18"(:60;<2(@+,!A96?B3-/@/8?1
@r8751
NCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCC
+
&$'+(""+&+%*+&%$*&#$''$(##("!*%")(!(+*"#
@r8752
TTCAGCCGATCTGACTTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCANATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTAT
+
9,D3HGEC:*4?$@@218!?@.=/F869#E!G$)=$$5BC8G#G''F!A;7BG:6*!FC)%1(;2%1-3EG=9:465/>D+H'*?=0(?%9A/85+1&4?2F$4G61
@r8753
GCTNTTTTNNATTTNTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAACATTTT
+
'$'&*%)(!"$%))(+)$$+*!+'$$*"'*%!"##*#)$(*+%!%*#&!(#++%'(*#*&#&!*%$$&&'#'#&+"!##+**"*!&)&")"()*'&$&)&(+'(!%&'++$++)&)%!$$%(
@r8754
CGCGTTCGGCNCTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGACCTGTNAGACTTTGA
+
(&*$'&("#*+"!$$*!*&''%##&)"$$+#&(%*(''**!"&&")*!"$%'$)!#*)%%+"!!'(((+&*!&#**('#!$#&%$&"*+#$&$$%*$($&)'*('(&#)%"+&''**$"'(&+!*(%$*'&'&*()'$&!%&!%&+'''$!&$*$%)'&+")%("
@r8755
TTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCNGGCCGACG
+
8(,1662)-237//3B3-5+%;!",:"4/6*8B:4B=3F,G/E*#&0$$>,=2F.6&76:F09.04'GF#E/@%;/(2=9#;88.##0HD
@r8756
GTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGNTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCNTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGGTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGT
+
.GH10/9;0;+G)1F3?9E?@(D.E(".<1&$(B!A11#!G)FF;<H;7-;AF8A)E?8<;'"B1$@.<=2!/+G;5<H5)'))A&,-D%F+7/=<!1*BE;'42;$@C/$721+*DHE/9:-#9--",8G'9D#CB5C=.*)D/!G,:+5A-"BG*.*3!9$F)43@5$9:"2<3=7D"!=D?:<<3(C?2>(13=:>!A30,$:(B.;.:+F$G0)&%AE4@73"&(&3*7-AD246G+F8C4796E$/5+%6.B!'@%$>%"*$;$FA0&114>.H;B-@&*">/
@r8757
CCACTGCCAGGGACGAAAGTGCAATGCGGNATACCTCAGNGGCGTGNAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTAT
+
+#&)%*+#!+'+*$(&(%#+'"+(+!'$*"'++"''+&)("%%+*(*'%#*#%%"(+"($$%)((*$#"#&$&)%$&!*'%*!"!%+*#($&%+!*#&&"#
@r8758
GCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACC
+
B-3#$$4805%".B'-,<,%1-"87:H7E#;*2@/#)=)*0G.E1?A<&7.EA,)(&22!:)D2%>$.>E?2F@26#F<@8A7486=;=G-
@r8759
GCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAA
+
B&)";&(19!"@H#52=FD&&>,&C'268;#"<&0'C)&"BFG)9'E!H!F'>@+'%>>426>)G4B4"09%./DH
@r8760
CCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACNTTCAG
+
<3)>=B8!*=><6B>H7H2.:9)<933.,'<<+6<AD#$.)'H:$(F2-C'F5FE4(F,"A<A),F-2AF+A<+04%708;6*0=AF;2C)C
@r8761
CAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGA
+
:?1"4:D4!CB;.06%(+02#)(/:+E$='5-&0,>.>(A="3+42F-$)=&
@r8762
GGNTGANCTATANTTGNNTANAACTNTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGNCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGNCNTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAA
+
#%$$'##)($)*'#*&#'%)'$'#'++(&&"#(#+#"%&(!!#*#'(&($+'#+"*&)'+*''"(#$!+(*$&**&#&(&((%()#()$*((!(+#(#)"#"!#+#)&%"#%()%&$%&")"*(!'+%""#&#)!$$'(#)(&!!!%)'#*"%##'!()))*"$%&%&'%&+!'#
@r8763
GGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGT
+
"6@5BC!:1>(/"2*??98:B7EF>;D0((H+9$.+!=8A0":"!0E/17(%,+/%$<$(A8?'4>.;0=5FD&!E"H<""3.
@r8764
TNATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGNGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGC
+
*13H0';#03/?='428FB2B<ECC+8(2"!A0H7956C6;+7'6/'2)2$G,5F@A+G('4C"@")>)/C-#9%52&%A-9:?0+3A;.5,#03>@58;G7%49>.4
@r8765
ANCTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTT
+
*#)+'&)'+)"&*!$(*+#$)$!$+(##&%$##&$!"&+!*+#$'"""$(+"''+&**(++)$+&''*+(*$!$+)*'&!!'$''#"'"+&!!"(""'+&*+&+%&!'#"$+'&#)'#+%'(#$)'$)%#+%"*'#"#$**+*"##)&'((!$!(+!
@r8766
GTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAACGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGAC
+
40G!:$(D@&BA1")..+3#"+91E!2*F"04B!A"E,@1$9?H+H-@?$D8%HG#@A0>04D(>!83DC?E(2;>H.)C&)?1B)#,&$7-<C#A*305%!F!&;%)2+69=&.;1$6-9,@<,)&$+3<CE17!/336,#-&)4>FFD,1"F81FC1#'?-#2>$'"9:D@84/G*5B$:4$$#$1C=.5E74@>B>)6#6)G<H.7@:@D%5$#B7.4H%$H./EC14A/F6;9'5*BC,"%+5&@#4=
@r8767
ATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCG
+
)B)D71<&/D>6F5$!(:@7D:9,)F&:A"=*"::>!!!-87:5!!*/3C&D+?-&&;B:>+59.(G3!0(G/.'%*-()!7,;-;4*@H'=.;&,$2)F,2<,CF2
@r8768
ATNTACNCAGNGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCA
+
(&&$#&(%&'!$$+)*&*+%&'##+"(*!+"#(*&+)#+))$*)&!""%#"!")#")!+&
@r8769
ANTCTTTTTCAGCTCATNGAGATGGTCTTGGGGCGACATTGTNATCATATTCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTNTCTAATCGGNAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGT
+
")(++&"'+&$)#&&#&)$"#**+!$*)!$##(%'&'*(("+)$&#**+#+)&*#'#$+!&('')'&'""+"""**)'%*+'"+)%$#'+!)!+('"%*##('&'$!#&&+#%+(*$#%+#&(%'$#%)$%&$*'
@r8770
AGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATTTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAG
+
,:472:5D:/?.+**-#'7E!%=:8"#%"B7,9HB:4!(:C>/?+B3D29H*<80231"&6,7>=DHG?64-BAA,F&G5;$?G$5(B-,=A#=B5;@<'E<'<4H-".4.:&4$68*+'<-9C6H2#,%5%B6A5!!C7,;E#<4##
@r8771
CTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCNTATGGAGTAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCT
+
+E<CD1-?=:E$%=59F15)6*7.3"(@$:(G8H:G!H$#?4;)!#A(47')!6@(0=8.7%,&G<':B?B0!$$4G450).!">B;<':<+4&6>&E(%7FC3209/@%=$B-$HD-";E97%@3%D'=3
@r8772
GNGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGNTCACTGTTGCCCTGCGGCTGGTAA
+
<2D6;A&;06GC-,1A3'D-HA?.4(G?:.C;%H$=C-H=G#%:4>,HB!C+2/71C/>86(11!:?CGF69)EE"570A#7>:
@r8773
AGGCGGNATGAACCATTTGCATACATTCAATCAATTGTTATC
+
$#+$($''%'&("#%!*+!"%#!#&*"$%)'+"*%+)*'!$*
@r8774
CCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCGGTTGAGCACA
+
),G9D@392=<B1-C=<F:%+(!14)G15/:@307*H>+=GC;/-4C/=),B68?
@r8775
GNTGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATTCCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCG
+
%$+#$%)*&*$)(&$'#!&)'&!)$#$##!&+%$"!'!(%!+$&+#!)"))'*&*#&"&*(++$)!'*'%$''*'*("$&&(+*&*)!%*("*%()+('#$&"!+)*$(!%*"+(&*%#"*&"&)&%&$(+#%&"*!)#&"!#+&$(!%''"&#%$""*((("+$&(&"!'&!+"++%!'%""*+(#)#*!(++)!)&%$+'*&''(!%+"')$)"
@r8776
NGNATATNGCTAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGNGNTTCGCTCACTGTTCAGGCCGGA
+
!*!%*"&#%#!#**+$"$%*#'+$''('*$)%()&'"&)''#*%!**"*%)!&*$(%&%%'!((')'&+%#+(!)#
@r8777
GGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTC
+
,)F"(?-F(#@8H*0/36/D*(7")9?'#!/!5B)./+7'B9/#E
@r8778
GAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGNTTTTGCNAGAACTGTTTTCG
+
@..7+H'>.H4E>%6;ABA54DD@A2G=)BCC:5&+#0B0=HF!!.;/?;+.,*=54C4AA=AH!@$E/$81#G@882'/640D7><13;%($+?-E8#!
@r8779
TTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAAT
+
/(=D,48>"0,#<$()'F;<0>;$(#=!F61--E@G>3:9G?"E$A4F..F#"3%5
@r8780
ACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTG
+
C9$-A%/7"'$/8;$H;0(4&"0D2H%A$33.@&B"G5"!&,C47%8HFC-3>3?H2@.>7(H+-9!;0(28$591@-"*-775-6A55=@*'+@7&.<8:>,;B?A:E(!)@>"3;!,A,&(*73H!F@0!(BH*1.+;B3%2B8;*?:(%1G::45HDF?%,GB?A;,#.(0B#$3*G*8%2F2B5<.-@-:,'7#&?$8(H?6E
@r8781
GGGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGATGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAG
+
"&43H:D+,CB(H6=?&<A2A$+,><F,00(@23B<7%*!?6;?**>>1<AA"(E179#A?=3)6:5:2D1H%A8%1)CD0/;@EEFF#30.49C1*";#%#4F
@r8782
GGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGN
+
H#E41>02%)5==11'A$/>1@=50B7'':+>2EC;2>A*C8;
@r8783
AACTNNNCANAGACCNNGCGGCACTGCATGACCTGATGACANGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAG
+
%*&!$"")$(%$($'$&''*+"&*!')''+)'!%*&&*&+#+!%*(()"!()!$#'$%!+)%(##*(%!'&"$$+$%(+$'*!$*$
@r8784
ATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAG
+
>80>.*/D21;D>>,H*.$(')E:31%$FBH?!=(0*6*2%<#<H90F*?E>8'@:229:--F$G3/=$;@$DBA<D!@F(*F&?B4&AC-/&(6#&3:4:(&@.&;$D47;8$F*&:9B,517.E:);H9BF<@'
@r8785
GTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACNACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATA
+
4.=+,<<7*:<('D=41!E7G6G#045)2#9GD+$(#5!CE>%3D?*>F6#)+5)DFC&*A6-G/3F2$B)4+&42A&)#.<)(6*6AGEC/5)47;<,6!1(9/3397"H:$A#:=AE59'*:6>.8,>'F:?4F=&7%A=:8+(9-*"7%D++>9F"D+$F;'6EA2!/$@61"<A7,<>B4
@r8786
TTCCAATTANATATCATCATCAAAAGCANCAANTTCATCATAACCCGCCACATCCACCGNCTTTTCACGGTAGTTTTTTGNCGCNTTACCGCCCAGGCACCA
+
&(%(!(&$&!$+*#+##%"'&&$!'$(*'$*$!"!"!!)++"$"&'+"&'+'%'#!%(*(*+$)%$(!#$&''"$$##'+&&$$'#&'""'#%++"("$((!
@r8787
CCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTNGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCG
+
C;B36.=2C!$?"@2*@<;2:=?1>$AD*$H9=B?7D/?B/*$$&?H,D$H&-1%*=E#;F::-8&+&:D<'.+;!>B6H5+*.>+E+B2G$E/7B;)BH+%B,C&GG"@*?5-HB67)%2-)G&.4-/+?#CE:F7GG9%H)9;6*/3%%"0A83&!GD5:1>$'29(+=,8)1!8D(D&G:A9?'(F'D:-$
@r8788
AGGGGGGGCGGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTG
+
?C-2DC/-DF>%6'3'<0/$5;C+'H%50F#B8/99.G9%963&$0;")42()#)!:
@r8789
TGTCATAGATACCAGCAAATCCCAAGGCCAGACGGGCACACTGAATCATGGCNTTATGACGTAACATCCGT
+
=@!#<!&/HD>G@4*D/(8+</(2$A'5=F"55G23ED,<A,@1H6DFC-9D<<B.82C-:7;"8'<14A-
@r8790
ATCANCATTTGNGCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGNTT
+
(*))"'))'"*'#'+$'"+"*&++#+&(#'*'*)!!%'%)&")&&%!!'$(''+(!"##!'((#')()()()#+*")$$!*#%'&!#&!"$#"$%&#*($+*+"%&!%%"($#)'(*!%*)%%%"'!$!)$"%+++))+"##$)&+*'*'(!
@r8791
AGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCC
+
48$5!/$<7)4(89;E2;60&+%%.49!G6=);"(8>"'=*?"F'C@/$H-!##BG>89'((('B)3)9#;2@C""'G,7/E79<+/*73)"B,*,1>,8-6?.C"67%*4:'1'<',0A7E&29@-<-&9A!387>7:?!7,$9$28F5)>;C.5E
@r8792
GAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGA
+
9G,23/5-,.>8"',3":CB?$58.F3,5=3@B.-$$C8F#FD?C!G?@'7G:."?>FEG1.C7G43F!-2>FAA4A8)&.$6*+85C'G;?$%&02#:9H:,$5>*(6#H2>0F7;5>D(@5B=/>3D4E*61%",B#6$2)5.#9.*E)=-2B&'>)-H-7?63&&$>'7'E(=6(E>A3H11)GG=::*F()!/AD:*B<?BE?/'(CFC&(-.,*D7E0+)<5:#=>)#'?#6'&-
@r8793
NGCTGAGCACGGNGTACGTCAGCCCGGAAAAGTGCATATCCANCAGAACATC
+
%?89A!8%*>0+CD$7&D5:AH5<8365@>;33?7011,*C3HC?8C3&7(&
@r8794
NNNNCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTTTGCTTCCGTCTCCTTCACCCAGGCTGTA
+
")"#+''#''''++%#%!(!*!)%$%%&""&()**'+$)"'&'(+!)'+&($!'+*#'+)(++*))+*("#$$+($%"!$*%&!))&"!#")')%&&*&&&&!'%("#"+
@r8795
CAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATANTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGNAATATGGTTTTTCGTCATGTTTTGAGTC
+
46"H*E%'E1%('2+*)?60#A:2(H<&$4-*=!&(:*-"".AA?2@=>B+0>!GB-22-D?;1G@;')'/?*7G4+B/A==>3/9/'<.:AE7>?<!-601(F!+7$((
@r8796
TGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACC
+
"%%+*(*((#"%$"&''#+)!#%$*#'&)'$*)"&"#&"&(#$
@r8797
TNCNTGATGTTATTCTCCTCACTGCGNCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTT
+
(&$%)+))'*%%*%%$'%&*"#+"#*)&*!"+%'&)%#%&""#%##)$'!(%)''$($)$#!"%&&"+"$%()++''!&'*%&&&''%)$+!!!)+*)&$(+)'%%&$!"()
@r8798
NCNNCCAGACCCNNNCNANNANNNNGCNNAGTGTTGNTAGTNTNNCNNACTTNNNAATTTGGANNGCTNTNANNTCNNNNCNNANNNNCNCCANCNGGG
+
"!!$$!#!#!#$#"$""$"""!"#"$$$$!$!#$!$#!!##!#"$$"!##!#""""!"$"$"#$###$!!$!"$"!!!"##$#!"!!$!!$#$#"####
@r8799
AATNAATATANTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGNCAGCGTCTGCCCGTT
+
!"'$&)&&#&!+'**&)&%)&&$""*+"(**+%#+%%&(!!)+)+&)"!#%$&*%$&++*))*%"%"$%)(+*&"")"
@r8800
CNTCTTGCGCTAATTTTGTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAA
+
9"%59#A!/0#/B/.%!(4#(0(+)6-")0.=;&=$&6>.'<BGG=E%E(031H<!9C-=)B*#)F05'!AD+(@&0(;;/66.GG=(&D@3H5>:H*'EC2<@&$&B*"E>43'7"G4():+H>%9;)>@:)E
@r8801
GACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAA
+
07$$E?+=7**&>D&HA6DC)*D=B>2/"#G&+#8,(,D:*'0;<(##!>>0D3=B.:5&$<HA:4
@r8802
CAACGCCATCCAGCTACATCAGNATCATATCGTCGGGTCTTATTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGG
+
;?D><(D720A-F$+;,:8;>@@.9&A5(:8#5&+0'/-2A0+4AA$)+F)@EB!8C!;>2359-,(D69+@GE%=8F9&6=)E&A5+G?=",3-F1DF+&'50H*D4$:H>C.A3#+?
@r8803
TATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATA
+
E7)1AB0AC:(F36H1#3).F:3*/<@:3<",6=?9"/8H5;"?+A!H.B(;'C(##-:?
@r8804
TATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTTCGCACCAATACCAAC
+
3?#-047",!;H@&730=1.:+)EF!;F"=@8)A5+!->1?G26#.&65&+&79<%46B+,30/?A!:0@B?+H(;C8/E+B0'$%4$7'5)>;?8A&7+@BG7<CE-G.&;:=3.>4B!*");430%-46;>G9</*;58'9+,+9*!H=/(#CEB9)'!D3!E0!>'8FE0BA5B7>1E8!C8!/E8/,*@8>-DFE7/G4"5A9!D4BF)<C!D)21G4#%0HA(2GD$3":!4%,"&)*,=*H#A!<B
@r8805
GGCGAGATGCTCAATNCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTNAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCAGGATTAACTGGCGGTGACGGTAATTTCTGCA
+
7C2)B,#6,"2)#:AA;+,<"6!29%(E2,?;08D..:E149$FC6HB069+/!+7:2*&?61;,!6+G<*A:(E=!!EG%D:$H5F;:1C&E/6/B;1(+1<G2")*)H.>3<&)GB:=A3%+9H@<9B0C2
@r8806
CGCCGATGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACAGTGCTGCGATCTTCTGCCATCGACGGACGTCCCTCATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGAGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCCCGCCAGCAGCGCCTACTGCCCCTGCTCT
+
%&>+,C!#-:DH.#-<?;G#&:$47BG34$+.7?5'"+@D#%!64?F,F45D?3=9HH,!@@902@:G8*>5B/(E1=@H>4#F1@0DA,%2,2:95/>C%*398,#38(.:F))>54#48,H-36.>H+E''(#!F77G%-@4')?<31GC-*@"9F6(HH96?,.1()+:;E+3/<=2$9)C><7-#HG=H.-*B$6(&6!=BFF&'@(0"*2B=!!;$(2G-23$#,(D<HC5(8)&$A&$74
@r8807
GGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTNAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCAC
+
'>-(+"*---2!:D!?1#92:''H5A01#/DF''A8<=:/*H/#(7&86%:D?<(A2(C2&$7AB%!H"+1!'8:(C=H'G30G01G?7).=DC,CH
@r8808
GCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCA
+
93HHG-6:%F9'FD6A0(B?+A3'*+@.(D2F,C)%2</F77B7
@r8809
NGGGNTANANNNANCNNNTGAANNCNNAGATNNANNNCNNTGCN
+
!#"!#"$!"!!#$""$$$$$"##""#"#$"#""###!$"""#"!
@r8810
GCGTCGACGCCGTAACGNAACATCTTTTCATCGCCAATAAAAGTGGCGA
+
)$$'(&(($"%"+(""#**)'!()%!(*#")#'+&($)%'$$&*(+"!#
@r8811
GGTCCCTTCTGTATGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCC
+
+31+14'-H*;GE286GH<0"#5"#>7%&6?!*35-6<!,>3%F04$)5*H)3##B?H
@r8812
CCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAANCNAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGANGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCC
+
11/)#3>B('="5?%-0D")#>;<)@,F5.B2E$A&CG'2>96.>1&,8-(C3!9@9A;>.8=!)C65>*<35G4)>94@!3==-=6F/'FF%-E=C,3#C%67A<&:3$D-;6AB47CBHD-.>G&+>=)HD-3AD>;C"@(''.,!#-H;;#@
@r8813
GATCCACTCGTTATTCTCGNACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATAT
+
%=GCH&,EG<3#'&3*18>5>F-4@67%+4?*@>'D<?-3.>(+CG8$9/2'83:!6F1F+*
@r8814
GACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTNT
+
%-#8>D##0&#'7%G!5@-<&G**$+:<&-$753BB""H!87*807B#&:C4$/)1+:"<H<F88+6-(G*&A?0/'0
@r8815
TAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAACATCTGTTGC
+
+++*#*(&%%')))')!#+!"'#*#"(#'#"#*%+#$)(+%""+)'$*&%+$#"!'+"$(#'+*#%%%)("#%*()('%)&#('!+)%)!)&'"!#"(%$+!+)'%*"!$$!$"*$'!#)))(!#(&$%'"$)()&)*&*&(#+'*')&+++$)$%%$#!''"'#'%!"$%$(("'+
@r8816
NAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGNTGCAGAAAGCGGCAGGGCTTGCCGGATGTGTCCGCTTTGGCCCGGACGGGAATGAA
+
#C5B+9B"@4=30,"%7E>D7F+6:8;;7G=30$"?<H=.92109'>:4A4("4H+)(';8%3C6*+1.FG#2?66"F3*?@B%D,9.:*%@8C!.67!5DG(:$9<#*")D3D-8>AH@87'"1@#$>!D8+*#E8/#
@r8817
TTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCATGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAG
+
//$-GFBCH?'*>!,D">.99,7A48AF6G'#,".&=4H5C-CE@)7#(*'G/2C051;<H4&C-!CED7.B@!&$'.+;$"(*$6<+:&9C0<9C!H$8
@r8818
GCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAAC
+
%@/A67>/$"-*B!+1A17B/"/&91)*$)"D03:2,C'+)<<:4H9CF#<D9.6DB,E#(@8C=@7H633=.F;:2G@FF40!.#9":9)6'+A'4247->35?1.@*,CCD3;!,<C:-D#2#@<*H8A;@),>E&?+
@r8819
AAATGATGCTCTGCGTGATGATGTTGCCGCTNGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCNGTCAGTGCGTGAAGCCACGACCGCCTCCGNCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGA
+
77&7D:)EF'@G0C::&%F'=G(-*2%-@8*@.867'="BAH3&G?5.!HE85*"F,DH:%'<//"-"67AC15D(>09.+=9$7"-31./>0$C<<05G,<@G=(A11(E!$F4C&H7#E@=4$:%8BD3=,'%%61!#89*>H-F1D2//;;@!E9650F'#%/"8@F"E155=:@$/5$2''#4E?>(!
@r8820
CAGNNNNGNATNATGTNNGNTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGCTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTC
+
*!"%##!%#&!!%'%(##%"'+#*&*$#($+!&$+##+'*')'+'(!%&%)+%$$+*)#!!("**&))(+"!(!#)$'*)!&+&*$%)'$($**%(($#'+#&&$#"+)+!%)#*%**
@r8821
GGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTNGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCA
+
<')92.<5:>";;C;&"8&8A;2?*+(C$9&+(%-<F4=+#4!@@C)E2/?27';4#64C/=,-2?7&9"E2B5C*E&2;?4&(<-*<)8-H#0E8)!?+47#E0F-8+"F%@.#!95C/%$01B+(H$BC3"29>
@r8822
GAAACTCTTCCAGGTCACCAGTACAGTGCTTGATAACACGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTNCG
+
G*68.-1!3=&?--C'.!,#;1E(1HGA6@77E>#-A1?5+*8@%<%D&1DAC2?9C8$B!68H1;+;B5(4<=4#:$"G.9CD':,'2?569)@8"DE5#+-(D9<E&>?*,80C8:5<+#7H(@,01')!7&=&3-$8/17G&@
@r8823
TCACCCGCACCATTNCGCTTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGG
+
!5CA=F?+@$$4&&.;+A0*"(/HF&1'4H0H3-+E6&258G500:;+".F4819<BC"%&/E9%+=/G2G
@r8824
GTTACNNGGCAANCAGTTGGTGATTTATGCGAAATGAAGT
+
#)(('"!"(*('%$+*(('*!'!'$'#*%&)!"%$($'++
@r8825
AGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAG
+
*33.%G:FA.C5'1/>?2#H7.&'>F6(4%@'C%&78@/3&=F4+,$
@r8826
ACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATT
+
G'2=DG$=H*%/!A"AGE@F.!2A%F#2F$/)<'3-+G71E7G"C6,HCH&+4;F3?=/,03F13%@;2)8F*8>>$1BD
@r8827
TCNGCAGGNAAACGCCNTGCGCAGCACTGCCCGTCAGGCT
+
*'!)'&()#'&)$'%$)+)(*(""$!&"%$'&(')(''#$
@r8828
CGGTGCAGCACCTGACCGCAGAAATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGAT
+
/:G8=;D2#7B":=9D@1+E>%H4%795-G*&2>54D1-7-@C:@>#)81+-*B<B%/?F7(EE4363<>&5<G9,*(G6=>#:B/3#7%4#!HF&:/A$1?)H32(5-$*D"1+3%*
@r8829
TCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCG
+
C&E1B#/08,H-+1>,*6F:B;.'(G7!7/:043A-A2;=57((&7)(853*+E@7@%3%!83A)3++#B4DB)'0$!'*E"
@r8830
GCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCANTTTGTTCATCAGGTTCGTNTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCN
+
E.4+.5(=(&-H#D5#)>B&;%:#1"!G/26%#?.?3D<.B9GF*$-%&%:HD07@.8AD.B57GH<9407%&"$"F'4)(791-09.60$DCF<1;287;+"HD?-&F0H0&?$;(E+<"H9!#:.@A6"63D!*:.,)/7?%B5'358!><+?
@r8831
CGTGGAGAGTACAAANNAGGCACTCACCGCGCTCAGTTCGCTGCANTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTNACTGTTTCCGTTGACNA
+
E"?H@"B(D@6+FAD3#(":H!7C.1'/EG#*"'+*6)37>6"!"""B>(6';)0(/A6"2#=:((;H)8!1+@25AB)H?::5DB)A%>@";+F@7;#&.3'8.1=-8;
@r8832
TGCAGCCGNTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTT
+
>&!6%"%%4;+A%?+>&;87!;:$('=9<*&%63'G99E<,#B+77+B6*405*?F*02'6"$-E"-G"C0>-F1D2+B2/!G/A*<>2%B
@r8833
AATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGNTACAAATTCTCTCATGCAAAAAATATGTAA
+
H!+"?;ED)*,4859(GAH:4'=(-:5H2+-,B>C$'H')5#6/B>!<4?G:7<.2,2@/#(4H.<;@B'>58@@=!9&$D'FH4$(A%$89E8>8CFD1DC#;691-*@9$<=37:*7,0=C'@0H-9&9?H'.4&,7*@6<>@3.)/!-<DD.4A$7=D;"!B*2G8%,.2G+A-<3+7?H$/3"!&C%:"8+'?>9EHD(5!/2F/9-F*%F'!*(HH.,8:-(9A!>#16/-?2D"+1?*08"DC(,@>&966EF,B,):2=A*9/D8@A695.5*#*',-C$>E+#"-()(6((+3@%,HH)G7D..#8,C:$D),=97F<A)@%!(,B
@r8834
NAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCC
+
+>*()=&D2>A2#'"09B'#'-8.43E@>00B/)'0HA<0B>
@r8835
GTNTGNCGCTCATCATCGGGCTTCTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGTCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCN
+
"'#!#+%+")'#(%!)++%$"+&&%'+!()&$!$!!*)"*!)&&""#!!'$#&''*(%#&#'#$#&)))(("+&(#(()!##""*!()&((#!!$&")'
@r8836
AGTGAGTTGATTNAGCTTGGTGTGTTGAACAANACTTTTT
+
(+"%!()*+*'+#!(&+!#$$$+'(*$")+)!**(((#&!
@r8837
GTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAAT
+
%C%9-(3.=4<',B0*,'G55!;H96;;%$(!@+7-;07)(!(,;>B(5-:
@r8838
GTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCN
+
(*9!9/3=BG*7C,F8-F;3#GE3@%&,9=4C#,0(0/=<?9,!'8D+)#.E,>A(FB<EBD@6EA=<"'?2#1
@r8839
TNGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTT
+
)")+''*+"+*%)&!+$%"+!++*$#+*!)'$""*%#"!&'#)&%*)*'!&+&$%$()&%&""#)
@r8840
CGTATCCCCTTTCGTTTGCATCCAGTCTTTGANAATCTGCACCCAGNTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCNTGACCGGATGACGAAAACCAGAGAATGCCATTACGGGTCCAGATCCCGGTCTTTTCG
+
052'?%3CF$8+.9&H%EFH*AB9HHC:9?99HH++7*1G<=EC4;F:7A30H6&">F8-;&GA+6C37A@#4+F45/7%5"&0F'+>>!()6-;'88A@#4?$-3>9.=>C?;8<'"E<<:)@()C495-BF:9*,%?,5)).=>,#G6'$-#3B*+9:+--'.B
@r8841
NACCCANANATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCACAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGGCGGG
+
#)')%%$)!+"&+&(*++"#%&$(%"")!)!#&)#+&#(&%!&(!(!)+%(#!#"!')*%$("'+%+#!$!!'$*%$$!%%"%++
@r8842
GTTTCCCCTCGATTGTCCAGCCTCGCATATCAGCCGATGGATACGCGACA
+
E=)8=BB6/):1#H(<=)GH=4F>@=),H4*14>CG!.3%3;9#>,F"2(
@r8843
AGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAAGGNGCGTTTTCGCTCAACGTNAANGCAGCAGNAGTCATCCTCGGCAAACTCTTTCCATGCCGCTNCAAACTCG
+
&+&&'*'#")('%&(*&!*"+#&!*'$(#)!(*'(#)+##"'*(('')%)!(('!"$$*&"(!*++*%+&#)#&(())+*#*'#%#"$*)"$!!##&(#"%'!!$&#!&#+($
@r8844
CGGCGTCANCAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATC
+
:4B"&59C$?>C%2@0C1.)$H'''/GF#/=D-9@6'D429><$<+)7!5/%@$!DEB0F"D8AH0@*0&'">/+E#=,:8$B)*7"->%';#?"<)D)4-1
@r8845
CTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCACGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAG
+
<:(4=#"=.,H"5,<<&H))-HH@(G63@G272"=10B?2+?;E9.,1$?09!9-D!*88F;4G%&;>'(9()G#1G"B*A&&B,#H.
@r8846
ACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGA
+
/E?(!9+?B=5!!=2@95CD25G$7<)GH'(08#5)/#:%=>252'<H783ACD2>%
@r8847
GNNACATATTTTGACCCTGAATTATTTCGCTTGAATTTGA
+
)#!))+'##)#+&%*!%#'&)%%(*+#++&*(*&(+%(*+
@r8848
CCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGNGCAATCCATTTA
+
*85=+E9%>,$>/0"H@1;+@+F#@)ACC6/+:&;@))B'<DF7C9+HF
@r8849
NNAATGGCGCTCTGNAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACANTTGCACCGCGAGTATGCCCGTCCTCCACGG
+
"!+"$$(#+(#)#(+!*%'&')"$!*##$%&&'!*+(++&!(!'*'+%)'+'%%!'%&+&+!&"%'(())$$&)')%#''*%&)"'$$&!'+'!*!++!"&%&%"!
@r8850
CACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGNCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTT
+
B##A869-!=#/C%1"B)H7@(8.%2$$'??9G"9*>'4DH=3;EE5,8><;C13'A(&E3/#@C5"<C(C;,&;#'?-A5H,E24F>&,&=3,
@r8851
ATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGNCTTGACATATCCCGNCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTNATCGGAAACAATCGGCGATACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGATATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAAC
+
E:"/!59-980$@0/88)'C01C4,!"!0C5B;&#/6:-.%ED-H).1H=.>@"3B2G7=$&409E@;9D4H3CC%)3/"2:@?1+6'4?HA1.@B:%(6>=GDCF6"B8E6'!"?,BF,#329@$-/AE%D*'4"3>=?%'C8?3#'G=-36F'6D"A035*%H964).-779&(&5B=;HFHG9+*$B!'=2#/#(.2(.E57&&><"F:'7-2F(%8BA-CHB1,$:%3H<@G9C
@r8852
AACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTG
+
&2'<4?1F/?49A:<B/*5&C,746)F.0-*F&F1DE+7);'@
@r8853
TTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCNTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACA
+
;08G-,;(F9?+!;H7%///@EA&,9610G)>!'=@9'D9$1%C*&H/!9(>(.@B68!E4),B.(%0H8#4H$1%E@$'2<+>GA26G&@(B7@$'2(A$H&/%/%A8>B0H0<AGE#707,..8,(0+G?,9?(!97F29C8GH<=0$*B?=!B,#1D(AH>!FE!8284/0$2:FF5)2G$A@'B--'<
@r8854
TNNGNNNNGNNCACNNNTNNNCNNGGNTGNGNCNGNNAANANNNCATNANTGCNG
+
#$#$""!!"!"!$$$!!"!!!#$$!$#"##$$$"#!#$!!#!"##!""$#"$#"#
@r8855
ATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCNGAGAATTAAGGAAAACAGACAGGTT
+
A?3$0)%+<FH,":":9(<?;&+,"0CC26,)94%2=!*!@:.H2.!"!3B#92=D2356F$7."9
@r8856
NATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCNAGACATGGGGGTGNTGAGTTTACCTTCAAGAAA
+
-)%F!>,*4.3.((2?-1;-'@;4(#*+210:$:#,E'B11*(@C)1#=1=:7-+3%9&E86%1+?G;8:=4:8%>4@1G"')<F%:;$)6;@A&F.D*)730CD(,>)2,2H@/8D65!(2';!)?H;+C5)
@r8857
ATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAANTATATCAGCATCTAGCATGCAACCTATCAAAATG
+
GDG*F/&C.F)/+'#1*04,*4509FB%;?(&$/8%H%H/1<"->)6#2"=:6D+"78=97(?G;$2=240?@651
@r8858
CCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCNGCGAGTCACTCAGCG
+
?1(D?3?(1(,62C+H=G3%2<?/+$6!"F(37#2&#49/1#6#>7+5"940A>5*?
@r8859
GTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATT
+
C6B@;'D2-@5*/,#A,?#09%*'!HC?%!D6G+7-*="=@7.@=',A@1"F*'
@r8860
AACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCTAGGCACTGNGGGCTTCCTGAAAACTGAAGNGCGNTTTTGAAGGT
+
*6@)2:1B,!7&CHDB92?=2EE+A6?3'E4"'!E(;@(0D$3>&1<B==31>'#&#9@884<?4E1)(+C%%?1=8C1=:.*,%.>5$=A-D$9H$)@>F,&
@r8861
TGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAA
+
B68")8-6A(1:/6(@%$//$:+D@ECGC$52$*!>&@F2,"!9G1D:#+.'#9B#B+F701=9?69(C+?29!"98"D:=B$/CE!+B.6=#;(7D4?(,.+692@6D&0$E(/A'+'6)H5;"-:?9#.2?&G2=/BB&<FB(5AA9""("EB"<"30%%(&*'%4E<0<F>=))3$HE.H70"B!%*?1)3)0"
@r8862
GCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGG
+
,(C=)742544H;4)BA(FB$>A>&HB6?+4F@314:34>
@r8863
ACTCCAACCATCGCAGGCAGAGAGGTCTTCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCA
+
D$>!3->H<C#6:G*A>+082)A3/;.#4)7"5:9:9!-'BE#?CE'C8=$3E<1#6"6.'=C>6GF=9?%D.7('>E$F8,B9D2$D.BA&CA8A.<A:;2!BB
@r8864
NCATCGATTTTATATGAATATACAAATAATTGGAGCCAACCTGCAGGTGNTGATTATCAGCCAGCAGAGAATTAAGGAA
+
"$+(!%"*##*'++)!*+&!)"%)$"(")$""&#$*('%&&(!'!&%%#!&%"&!"!%!##%*#'+$(")+)"#&+)+&
@r8865
TGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCG
+
7@),=.4-A-'BHG!E,75;2#&@:BD:<+6/46(BE1B9:2+5;!DH:()><*FEB9CF>;,>;(1'=C38CFFA0>95
@r8866
ATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGAC
+
)?.A)75F+!?)..!?7C()D7&92E(*D3'1>=,'C+!*+'3GG*
@r8867
AGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCAGTTAACATGCAGTGGACGCCAGAAAATTAGGGGAAAATCGATTCCTCTTATCTAGTTACCTAGATATTGGCCTTNGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCANGCTCAANCAACTCACTAATGTATGGGAATTGTATTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCANAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTTAGTCGCTTATATCTGGCGCTGGCNATAGCTGAT
+
!7:5,:5$4F."/=C@.H*C8/$=%+(3,)')0.C2@.,($?#AC,(%E%)E*;>4!?>E-1!:FE??1G+73)<.4;0*,67'G"%(;1)G?"78)CEC83>A?*2$@%(C/6@0#E2;E1A#<,F7?8";?A$%H;2.E0GG"-;5?&7AD;9:;!0:@%A2*8B>)!,=66*$1%%*&B><-F+>&A7?<87(;$@4:$0-/@G:1D,'"-C(EC,@A?1C,'1H)&$FD,#$;G'#-!01G>@%*DF8D9'4)?*A1>(.#8/90A/E8:5E=@E"0*3,;7D+D)%.:#C>F2C-,&1H5('G&)D85CD:D8#H2F8101(/FHC"9=#.,."2=.9,D)6*/)H4::2,&7)*15>EF?D*#')/$/1$D-=H4GBH2H$7D#&6:(@?-;)H#E=-3<31:1-=G%@0:3@!+E?8EA":>E$CB@6?$%*80F3>10?&(1.H=#5C
@r8868
NACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGNATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTNTAGTTAAATCACTGAATCCGGGA
+
%;/8E:'B9/F/)*@D3#>3/'-2H3AH0!=/6-#27)'F::3865.%$29+0!!%;;2<&/#/<4$.;3"+,>H,";)F,7%E>,$*B&%0'00"E#E>E*/#,F=#D-)G+E)@EB->>BC6;7*)
@r8869
AANTTTGCTCAACATCTTTACTCGGGCATAAGTCGGACACCATGNCATCACATTATCGTGATGACAGAGGCAGGGAGTGGGACAAAACTGAAATCAAATAATGATTTTATTTTGACTGA
+
<C&$H(A>A8"A3/95D:0HG%%,<0,3;#:5?9!4("DGG/*60?3HA;7,F$D/1@;@9643'$$A@FE7)F>$0*!A/:5D<//*(84F,,&4#$=;.."/=H9$9<C4+,!*$<D
@r8870
CAGCAGCGCCTACTGCCCCTGCTCTCCGGGCTTCCACGCCAGTGTGAANCTGGTATCTCCGGCAGATTTCNGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCT
+
D2A8GB65:4).B$.=8<!E*:A(>$2B'.49H2=4C50G20G@#E#CH41!"*;48"%(6/,575=4)'<5"F&0B)B2AA3@38=8F=46)'4A8()"*!'
@r8871
AGGAANAAGGTCGATTACTGATAGAACAAATCCAGGCTANTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCGAAACGGCNGGAGGTTGTTAGCNCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTT
+
6.!AFE'9$BD$F9,362#$F?)#=/778!E5&H6";1.1<@;?)::/8&HA#@.84:/%&A+49A?.AE:&D#!>G:28"A*(@(/<A%8+EGF,G0AH!*#>DF:7)%(G8D@!5E2?":$>F>:#5<;&0:>'9::0457&G);44.5#,;38$1+,68*G/39FA;,%-!64'@#>$%#6"51E*#1'.@<=6HH*?AFF
@r8872
CTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACC
+
7./<3"4'<F9)5.@,@00)>!,4?ED@$9;8512-AF.?)@5',A+6G.@/#G;6@"/<5"G%,!5&3FA?2,:F3A<>A,(15"%"1"'@F/*6H8$0
@r8873
CNCCAGCGCGTTCAGGCGCNCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCNGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCCGGGATTTCTCCTG
+
(+(')!$))&+'#&#'&$"+*+(+&*')$"%(+#%!&#(#!)$'$*")(%!%'"#$)+(&"*')$$$)$$)$+&&$+!'*')$+%&(*(##+'(&'+'#*(()'*+!*
@r8874
ANTCCGCCTNCTGGCTTTTCCCGTCTNTNAGTGCCTTGTTCANTTCTTCCTGACGGGCGGTATA
+
%!#)&()()!#!&)#+"!%"'+#"$)+*&'!%)!!)&$)#%)(!$'&'$'*"++$*$!*#*+()
@r8875
TGGANCNTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACNGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACA
+
#)#(&(*++*+'$)$(")**#&'!(&$&*+"*"&$&#'!(')$!'"*+&#%$$)%+%()!%*'$'*(!!)++((*"!'('+)!"%$#)+%*''#'"")"))""$"&+*"#)**!&#*$'("'&)+(&)%!
@r8876
ATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAAC
+
#H,B+,<C3-.E();F46%:>0,DB"B>B;=';1BC7FHF*41#<:*E/7@G6E&+"G?20HE64;)&00$(<#$*<+73G?,=0267='7H*E/#-F7-:E3#-A?)#($63/'G!'6-'$+(2E5.8#%9#?&'=AF6G.>B)G@??C22
@r8877
NTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCTCTTTTAAA
+
#G,D4*+$B/4B:0?+30!@(!2-.F=8>5H&,:)F+F*>B17?;*F?CA69!7=#B'?,(!>B/!,B>-F8F+,>$D5/;16!:&=96*'38>!C.&)?(8D<#:#2*),'3.1$>.8326'@DEDB
@r8878
TATGGGGATGGNGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTNCGGTAAGCACGAACTCAGCCAGAACGACAAACANAAGGCTATCAACTATCTGATGCAATTTGCACATAAGGTATCGGGGAAATACCGTGGTGTGGCAAAG
+
5<1&:+40'2<:0#9-9(D69C!/!D%H+>:/%;5+15(4B@A(?.:225!&@'>$-H&(3>,9!&#,2@?/F:C)0(G*G7,#48D@837/5!*C0A@$*26019*A/$.78$3%"=!1--?=;;&E<"70;-=5#C?(/8-EH>8%
@r8879
CAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGNTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCA
+
1#?G673/(5,E8F@#+B)4-*5$6#H(G+:/?5:8,8""-9=<CAA)+#?0,B)+8;60,#)B=(#2%+>+7B?3)B60%
@r8880
CCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCAGGGACGCGTTA
+
>#);8(7,&6!B9H&3?.,1E28@48<5=/BB&FB.4=*9..G#G93#+3'
@r8881
GTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGNG
+
/B"#9H8-B7.+F+%!$'99%6:F)=@%1-A89!$81('&?!AE6E,=FE+9,=023*H!1=/!F".0C+0,):62)DA=@*
@r8882
TTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTG
+
E16"12D:B',#3?@<:;=(:":=@.=)75=%6F'HG2$H9.?B:FE
@r8883
CAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCAATTCAGCACGANATGCGGTGG
+
GB#7EG@+=8$?3'?0%5"H1.@<9F516@%/2F7%"75-#->;784%,<-&6E8E"C-70254C!,;#9H5=55-
@r8884
CTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAA
+
/>%*%*-3041#33:?2+@7(;5E*D8950"F5%7+6EAEGC1%F12EHF2A0B%,AF!>;03:(,+&?@CBC'8:)'@G;'H44=CHB:=%->%9!D#$D%?D,03>2&D7:+5EB<=90#7/:A+B
@r8885
GCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCG
+
)'8=+25.DG4&%/1F!&&#2/"'+C&)AC#18E1#B%1+="6D?39##:H:AE&C">75G"5:'29%881?9#@BA&C3!H
@r8886
CCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTNCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTACGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCTCCTGACTG
+
()5+8=21B0))?/G(5F(D*"@@<5$9:2)5!@;-B(<#09)6%6E%&2"%'A>79"@7/>?:/D0'3G1!&3&E<B#G."61B(HA478(2A5-B!)4/)9(4BBD/@9@F33.;/+::3B1F631G;7?"%:*.;%(AH(HCE3(GAE795-6)#E&$H1%):>9
@r8887
AAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACANTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAA
+
(<7+:+2"'(2!9#?.D!&%;D@85/A;-%-;?H80H>:F"+.%<%:@.3>7+H'HF=G<E(=F%G&E!*)?.#2HC52+&+"<%C3B47B;+9.'<F:;GA(>10AA2(D?08$@$2@G<"5'9#A1+)F9"/;9C(:C*86>
@r8888
NATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCG
+
'$)>G78"4'5E/B<4'"%:$!=3.8$FE;(78FF!2/,3E#H@#:A=3*?!E1'/1!"*(2@@=,@#<@&/8F<&67D-$BB2@!E>9+87>3CD=8%&$&,,5'-@!*
@r8889
CAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCATGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCG
+
%C'D<A&08$AH*<,".':"G;("2DC;>$!GA786@4/3"(?4G25BA(CE!GG-FE'G+(27A"(;%<?-$-+EH:'37;,")/A2B6@'@C-CA<%AA>A3E>
@r8890
GNATCCCCGCCCGACAACGACGGCAATGTACCCNGTTTCACTTGACAATANCCCACCGTAAACNTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACG
+
8)($/E#HD-%&0B:E6/B.AH6%6(D@?9-6+.<(>58;E+"1G:.9'7%23"694A<;768"H5=1F?!:+4?<,4C1=F946/6!(>$A"G"78D<3+?:59*6%?12G/9F+H"2)&','E+65=.9,1GA@>C#F37+B7,2#@*D3/&7!2E7$%$.+F=,71,-ED9$;->G,@:376="+68#.
@r8891
TGACGTGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATNAACCTTACTTGAATCGAT
+
:1GGF89+@)';?7:2;4-.F"/E0+7/9E)?<9A5,06669<-A/;82/<=!#1!:@38&806@=7=FGBH8*$
@r8892
NTACCTGGTTATCGCCGGGAGGGGAATATCANAAGTGGAACGGCACAGNCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGACGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCTTATTGCGCCGC
+
!+'++!'#"+"+"*$$))'#&)!)'""+"(+")+""+!!)*"*"**%*((((!(($')"%'%)*()$%!!)"#%*+(#"%!&$&%++()$%*((++)&#&)(%!+#)'&#$"((()"&"&)&$#$$'()%)$%!*#"$)!%(++"(%$!'
@r8893
CCACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCA
+
"00,@>D+73'-69F2D=C:)9E7,+A3&"HCB>(D(B!G4-E!"!&5A&B9:$(*<@(0D5.",%=H/)7$E$2:$-<.#(/?#E?9D(7$">#>;F+A?8=88FH?0B:*2.G%
@r8894
TAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCNTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTAGCAGTCCGGCGGTAACGGATGCT
+
7-G/":89#&E"'H747D-18)2@A&%1:2$*'3></5$A@E=/$>*-+19>G=7C5/%2$-:557'(H2'<"-H)'>C'74A,2GG'$4,->(?%GEB(A0:=/)057-A,:F&!!B?:(/#'E./)G=*=06E"3=8<4@H*CB/9B8>G1>$!)3?*38,<92H)*8
@r8895
CTTTNANAACCAACGGGNAAGNACCNNCTNNNACGNGGCT
+
(!'$#$$&($')!$(&#%&$""&*%&$*"#'#&)'#*++(
@r8896
CTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTTGCTCCGAGTCCACCTGCAC
+
/58*:-"8B3?/D%(9B%+(7H=7<*-;5!6F/4+-<BGG#(#-><8&&C'&#.&5)0--?6F):!C:
@r8897
GCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGC
+
>:6!9%C45E@:*;B%7@0>=<#-*D6--D-3?=,.%82G+7@0#4409
@r8898
AATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAANCATGCTGGCGCAACATGCCCTGCTTA
+
)*@1-G7A/+B2/F;C$=D7;A57%'613/%EA>1F5'-)E'H>32&51?.8!EG:A6>@9.27;D$FD#8?
@r8899
TTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGG
+
<0*+;1#+*%<22+%%*?5G0>:!?:""E.4:1-:((11@1-E"3*81-#/0=';
@r8900
NCTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATNAAAAAAGTA
+
,$FA*H/A91/,//?;+/"0B0CB2+59&!*1)-01'>=C"$9B&4.:.>A"B'+G.B-?%-@:E'BB8%$;GF-$;"54!:B1"3=65.,&*##2E
@r8901
TCTCTTTCATATANCCGGGAGTGATTTCCGTCTTNCGGTAATCCAGTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCAT
+
'B03$)F26&H$.@?(E'!54>:&6!D@GE3#CH>@FA.&6@F6"(-:GF@4*"*D$<3?HDHF#4H2B&;+8%+)C*8GE0$D8
@r8902
TTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATNTGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCT
+
93F@-D4CG<#6D$E(2;9F4B$=GD(=D8@2,G8,'#/'5D'>5E96!(1.A@'B)&E!:F"817F2&*6'6A:90F<-2#<?B,233DF)#40*.3F=%6D/C?GC5"G#=8G265(GF?*DG<)2BCB'C7*(C+8-%,99'1E89"/>+&05#(CH":(6B61"B&H!(E3>4+'709<
@r8903
CTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCT
+
*-:(>569E41>@/#E2#7B@/;)BA7!EH!G3+6A8.,G:3@9@C
@r8904
CGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGANTTTGCTA
+
#=F+=-=%1115C3#)5:66/A+80!<,E=:.2.C>/A*F$+A2BG=G%8E#69435G@;'BC'G>-%A8B094.:.FDG"=2
@r8905
ACNGCNGTNGAGCACATCCTGTAATAAGCAGGGCCAGCNCAGTAGCGAGTAGCATTTTTTTC
+
)'#$''(*'+$)+&+#$%+$%!##%&%)$&($#$%%##'!)")+')*"!(#(#+"*(+&(#%
@r8906
NNNNTNAAANNNCTNGNCATNNGNGGNNCTNCNTAGNCNTTTAANNANCNCANNANNNCGNCNTANNCNAGCNNGNNNTTCTNGNCCGGNTANCNNGAGGGNANANNGANNNNNNANGNCNCGNAGNNNTNTNACGNNGNNNNNNANTGTANCANCAAACNNATNANNGNACTAGGANNCAACAG
+
""$"$#$!!!!##!"#!$"$#"!#$$#!"$""!#$"""##"!$$""!"####$!#"!!!"##!$$#""!##"""$$!!##"$!#!$"!$$#!#$!!#!$$#$$!!!#""!$"""#"#$"##$#"#""#!#$!!"!###"!!##!##!!###"$"!#"$"##$!#"##!#!""$!"$"!!"$"$#"
@r8907
NGGAANGATGGCCTCCAATGGATGGTATCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTAAAAAAAAGGAGCACACCATGCA
+
$:80'G71,H@>6.<.%.5#$/-<,@#910A25@1"$0,-,+'"1/*0=-,!E01->D(/A>*@;.?,AC(.&2B2HE9@$)3>601EA+--(;,>+"(,HE(5&7"54%<C"B=9>6B;-62@74''"3*7")C1<-0@,F2/3=/3$9C$G)D'/)/?=H0.<A,8'8-$A38!H%)92
@r8908
GAANNNTCTNAACAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGA
+
%&%#%"*()*)$%++*#""!)%+')*##*+#)''&"&)$#&!)(##+!!!$(!*$*#)#''!"(+%'!)%$%$$'(+)*&%$!*(&
@r8909
TCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATNATATGCAGGAAACATGATTGCAATCCTGAT
+
&<@$5@/50<E1&,H;;-H*'D9*0>D?A(;*,$G52/=6,H-,<BE4()C(?-,!>+#*B,7A<#!1
@r8910
CGNNGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGNTT
+
!(&"+"(#*+**"*"$++##$&&*&+$+$!)$%+#+))*(*#$%')(#++**$'%&!*(&
@r8911
AACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGNACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACNGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCGGTGTTTGNCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCNGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCC
+
-9&7@@F.GG11D<F.#*G$.?;C!*5@C0$HC/;!3C&>92-:-&90'**#>*7!',D&1A!2*+&D%H0(#<GF-)*5%6BG.>.D268<)696'>43+3+B*F/+269*,:@!@B18C+8DCAAC93F+9%(D3"(42:H?,8-E);:;4<95=DG"&.4EC*'2&?94G(+=<@70?A#1!E)G!-*#%#?AB;+#>@3&62C6'/(>#<E!AE2F/:5%!9A;?2?>7@:,-(33@B(EG1"%%G$*,D98<(:F&-9*F$*DE#)G976%'.<2D;:DG:%33(4%6!?G.2<"F0GD//G'CH2;;4D4%@5F5:FG%1E+?/8G9)@'9A=067;5%$%@)"G2!6@7G*?"H9@&+F>BC?3-A',F@%#>:F-G(?9),B("*,D,A.;#)@D<,%<9)9+,+9A;AB&0/67+>D&6"D3+H6>330
@r8912
NAAATTCTGGCTAAAGCCTTGCCCATAACGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTC
+
!C8(:8DB+F(>E;,H5?$+:EF:;77#B@DH8,)$FG<"#%#?1&;+*D'=6A&D.!E$,7;;#!G6D'9G0:C.68+,=34&B>D*B!%+;D52>1:'$8!6F*4!.+F9)5#='E,31E@&%>!*2<A4?E5)<<2C5(,:G@&A+A+191B!'&%9,4@(!F(;:>#7'8=()HE)D?!3C%"D17-?>B49B#(H:3$(!1)A?@.'A<(7@H3"B
@r8913
ATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCTGTGGCCATCAGA
+
4AGB1H##(HC,:?A+@C&?G@8:D/:4<6+-.))=0D<2%6/,!;'FBEBC#/!B!:H3<9?F'AF)?6H:F740:&,,'8,=F47F':,0@E:,*003#=EC*-3:5490@D?1?G6'#(+4FF88*9A+/:$=,=!9#?79B<F(@>?/9?!)<>-:5/
@r8914
TAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGNACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACG
+
+H0"50$3B+?'BE-?"28(,!C);3'!!B<.'+#A)?9"*D>=2,D3?">0%4>=6%B7<$(;#,B15*==>$9,:
@r8915
CAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCNGGACTAAGTAGCAATCTCGCTTATACA
+
#+''(&%+&+'%!*!&)+((+'+('"(#!**"#!$!%+$$&(#)++%)"'&*"%%+&!"#)*!#*)*#%'"$"&(+#%"'%%$#%!#**'+#
@r8916
ACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCNATCCAGCTACATCAGGATCATATCGT
+
0,@'1"=0$C!,'6$:$0-A-<<F>2.)/*5>A1!*!1:,$8%@4@"44"/:/BB3<E?/"#)*"32**$)7G%<D#-&H91F!!-6..9*
@r8917
CTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATNTGCACTTTTCCGGGCTGACGTACACCGTGGTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGA
+
+(@>C/*=.@:,?#&)=-:4?/0,D<E0-@+6-:;2>@7*@GC@:#6*B6C-)A"93F*9'6$);1C%H?-1A,F;1@G-3"F(%H/F+.8)#+8(*5>"3/-((5<CB>'!"H0-2)(D-4F55670&>H++>64>C*8:6?5
@r8918
AGTTTGATGGCATGGACTTTGANCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATG
+
2B+!=3;#D0=,4.4@?"2!4&6&=8&?#-+&*!7B?FD/#G'@",E>*+<?423H:,D/G1+)7D,.:DC<7(8<56"33!7,/>+1$D8*<1
@r8919
CCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGNGAANGGTGGGCGTTTT
+
;@()3D)$@**0%5D"B4F"$('#1<4&<8=+-5#!*5&??4(EG<;B4D?/B:;?50($:G52/
@r8920
CTGCATAGCCAGACATGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGNTCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAACTTATCGCTAGTC
+
H*&59,#;"*.5B,3+%8:.6A<+:1.4=';(4C:"F;A?1H@(G,G$>%G-&6DD&:&.:02",)<'FB&!G?$@.#BD7&E'4B/3D05,72#A%/)$60.#/C(-17!6%H@0*%@FD.4"),?.9GH:+F&-B#"2@8.96%54D
@r8921
NAAATACTCATCATCGCAGATTTCAATAACATCGCCCGGTACATG
+
"!(*#('+%%&**(&%%!$+"#")&')&*(#!&&()"+"'$("#"
@r8922
ACATGGCGAGTTTTGACGAGATCGTGCCGGAGCTCATCGA
+
1;:.>-=+E=5A81#>"9=F'#BH%=8C>D$"6F5(=6F,
@r8923
TATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTC
+
C14>2D19/$2)*"(49%><#B0FD,(2G?B0;%%9&()"">9-3E"$=#8>03-:H-/7;>+=6*6!>!-70>>A.H(':)A#<;0@53=A&1H--A?@!.45BC@A
@r8924
AAGCCATTTATCGATATGNTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACNTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGANGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAAT
+
C,!5!-1H;,5D+5HD018)@#B*HF@'<0%86AF"#3DD<5@=,?3,1<>"(@2@DF/%1C=G'D4C+=07+F()H<!<%F#$4*C$)(-&=$9BD2"F=<*2#?=1?4'&$+DA.$C#H7"%4@&0HH::51,B2E;5C@DHAF+3#!1A'1@430-H@+0F//C;;@F"0C"=.73":6/F>/>21H:04)'7B''$68@@&=/<<2#85F<,G(7,D815E6*$#H<!E0;,G&5H"")>+,#;+);>(+7"5;-2(%E84;0(E?;)3%67D5$<F&<FDG,AE4.H#G&&2=:"CH)(:9#<#::?#(97;$BC
@r8925
ATTGGAATTNATTCAAATAATAATCGAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAG
+
,9'%E2#6F>;(<-;#:)(B*H"';CD!A,$0,D>72!5;;@2,-55BC/FC&1@=6!(C,:$1#1&CE-)=5?7,''$%7"
@r8926
GGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGG
+
B2607<76(&9&06A:+;GC%8;(>)48==&1+A<06:H5HH1.?%.E"&D8((:/
@r8927
CAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCG
+
A3%A,<7+!B"*>>E'>";8:C*5);*;F-<2(@C-,&2.;$#D$H7C5725075!+ACF1H1*;2468@686H<@:(9C+5EA44""%>2%%(,.(,EBA"5
@r8928
CGACAGGCGCTGGCTGCACAGAAAGCGGGGATGTCCGTCGGGCAG
+
1<58=$E5)0.)3'CB>=H+:"8%=+C;&"20F7;E%1"BE;?@?
@r8929
TGCGGAGCTATTAGGGCTTATACAGGCATTCGGTACAGAGAGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTTCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATC
+
<=&!1<9H?)>?B((HD&5./''E/73?%>&<D.7'$'#-(($>D;B>EAA+1(6/?4*0'5>4D-B'%F>2+0D-;6%$8!B7,@>E6E"*>0(,H@;4:F%=C87$;<1B+B,#-3'.>-&G*-$/A!B<%H%&:->4+$(>B8)=B@)'?!=E'F53E&41*HH!.?;1)D-.>;,A&4(4-8B.>.!7&4?,'!9A27(F7:H%A5'$,?.B43A=14?D4/@H?$"1#>*/E,$&+"#.!2"
@r8930
CGCGTNNTTGGNGNGCGACNNNNNCNAANAGCCGNCNACNANCGCCNCNNNAATCATNCGNCTTCANNGAGNACCTCTNTGTAANNNNNGNNANCNATACNTGNNCTNNNTCATGTNNNGNCCNGGCNNANNANGNNGCNGNNTNNNCNNCNNAANCNAANGNGNTTGNCANTNCCGGNNGNGCANNCTCTTNNNNAACGNNGTNAGNTNGANNCNNNNNGGTGGNAAAANNNNNTCAGCNGACGGNANNNNNTNNCGAANGCCNNCNNNNNNNGAGCNCTTCNCTCGNGGANNNCNCNNNAACNNNNGNANCNG
+
$#$$$#"!!##!$"#$##!!!!#!""#$#""!!#"!!!""$#$#!"##!!"#$!$"!"#!"$!#!!#!$!"!#$"!#$!"$$""##!$#$!!"$!""!$$$#!!$$"$"#""$#$!!"$$$#$!!#$!!#""#!$"""""$#"!"!!$"!"!##""$"$#""#$!!$$!!"$!"$"$$$!#"#$$#!!#$!$!!#!$$"!!###!$$!$#"!$!!!!#$!#!#$#!""#$!"""##!"$#"!$!!$!!"""!#$!#"$$#"""!$"!#!""#$#!"#$$$$!#$!!$$"$"!!!#$##!!"$##!"!"$!$!$!#
@r8931
AAGTCATGATCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCA
+
3%%&8#.&33*C:CB8+*?"2.=+2)<#D74D/'@B6<+'$!C*GA"$DDB.:#54**/9#2F"!!?9<)E<(%B=2*8%2>2+2&9;2..31/;A593?*050"0;A4'&6?>:C5%&77.=3H+G%3=GH9+@39?;0
@r8932
TCCATCGGCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTG
+
9&9?=#2=@;!2G?>E,-ED;1A!6*9$@=>F>;*9FH&B+>D!-A8;GD-3*(3,H'.
@r8933
ANGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATG
+
7)H9BHA;+A36#-F9)7&-$4/#A1*H1#").1(B7E:07$'
@r8934
GTGATGACNTCATTATAAACACGCTGCAATCCCTCCTCATCTTTG
+
#+%"'(*#+&$()+$%$"!$!"#*)+)!%#'%$$!!)*#'('*'%
@r8935
TNTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAG
+
&(&+!$!''"")!+$!#$$++%%"#)*($&")#$$+'"(+))!"!(*%%&#"%(+($'!%%!$"'%!)(!#'%%+)"+)+#%!!(#$'"
@r8936
TTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAANAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTC
+
33C*%6*?0@;9+@.2?%HF0!G'9?3++2,(!#<4)>'!'78</3H/FH%4#:6@=B9HA5(6B<4!F=G06G#H!A-$."82&G)1($;'CD;BB3<2,>.+02G2,95*'0D,?*'3$%!54G7F#>1-(D-B>E!+)GF.71/G8:)-=:.!C>3BB%'5@
@r8937
TGNCTGANANTGGCCTTTATTTTTGGCANAAATAACAGAATAAANACTGCACTGTGTATTCATTCCA
+
%%!*)%'%'!*+%%&+)'($)"&+'%#$*"&'#)&*(%+*&'%#(%#&")&%'&&$(&"'&""'#&(
@r8938
CGTNGTTNTCACAGCNNTTGTNTCCGATCNGCANCTGCTTTCGCCACCATCATTTCCAG
+
#(($&&!%%%"'#"$!"#*#)(()#$"*&$*)&#*+)+!%$('!#+'&#))#)"&#+#)
@r8939
TGTTTGAATCNCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGT
+
4B+!>"F(0H0;?'8=*4!.-4/EH-C8(*0E9%E@19495,D/=G2:5G,E3)(G"<:&.8,9,G*9/./*H(?!$B)!)H(C8."10/(
@r8940
TCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTT
+
BB%)B$8#*5))?*2H>.G*A61C"A%(9@"#""-C)3>>#5@%&&1$D9"DF?&&F
@r8941
ACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTNCCCATTACCAGCCGCAGGGCAACAGTGACC
+
@5>G=C22=>&4E'"43+&=0'6'5#GG)";3>@0GFB'68@@CHGGB5E6F+H$H?6H>5#1D5,B1'(%
@r8942
GCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGA
+
@#61*"?.:0!6=;@'FF.85+.>+6$(=40C>)B8/0!->H*0;?/"E20GD,#'(E'B%B?5EBD;1//%A9(0
@r8943
CTCAACCCGATGTTTGAGTACGNTCATCATCTGACACTACAGACTCTGG
+
%*4,AC@E?/*;+<!(%00=?%!&"B?H*#/&<C"/@>--58D(/*H;8
@r8944
CCCGTTNCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCAGGCAAACGNATACG
+
#+('*#!*&'"*(%)&(#'+'$(!)'"%)"!)#'(++''!)!)))'*&%(%#(%("!"%!#!'*++*(&*#!!*''$'"#&)&(&#+)%'(*+&)*$*%!#
@r8945
GCNGCATAGTTTGACATCACTGCTATCTTCTTACNGGTTAT
+
%&#'%!(+$+'&#+"'!$**##+""((#"'+*&&!%!)!$#
@r8946
TNTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTATTTAGTTTTT
+
,5C4D,@%3':#-4''7,3!B)C#)*:?,$)58>-?*"*066<@7#4C?<)4?AAD;<,*?;-/:23,5F!#'(;444A8%B-:8+<)3#%H/0/244B754F-2@-*BD!AH$5.+B'
@r8947
GATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGNCATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGGGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCANGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACG
+
=<>0E(3!;2>AH+)C9D>5@5B$2A4&;4*$062;D68!*-'$<"3"+@)!,-G,3"30&$42:,*G>CH8?#H.#A!@.1*C.HF5=&?&F-$0DB%03>7/(7")+C?*.F!%)--)?+;8H""E&*!$19<A;2#<6/&FF0#8+?E<E#:-10/H@#7@F35":!!3=F'5#>528@&&&F91(0/':39E#GH;7B%#783-1B0E@$D76#&9&808=%%<5G6(*2/H%*,F#=7A>.
@r8948
TGGAATAAACCAATGGACAGAANCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGAC
+
=D;)FG7%75;)1%H8*"B,%8@*;45.<H5:&'544(FB/82=)2C?,*%:-/52>#%=7<2>+"+<2?#$G:$$&@6+<38HGD2$()2C3-#@.10@'7%)CHH(A95=#C;-D,()<G604EF'#H"D.(DG
@r8949
NNCGGNGCAANGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGAAATGAACAGATGTCAAACATC
+
'"'%)%"++'*))))+'*&(!#)'&%#+'*%+)&+'+"'(%#)**#!)*%#+!$$%)"&'#+%+)&))##+#*$!%#!+*&$#!"$)$*##"$*%)!***+&*%(!&)"$(*$)%%%*+$!))
@r8950
TGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAG
+
85=@:29$#17GA/7*(24/;,>H"BD)%.A5+14<)$"&74%HG#BB0,)5>AEA,,*%:HG:6121.-"%'A5(.,6)7/#2DE8="6GFB0
@r8951
CGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCT
+
9(;';-D*&1G12!9ED@2?7/D7!<3:HB2,4A1;%=+=9+H)C.=.@>/5
@r8952
CTTGCANNCNGGTANAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACT
+
)*('$*!!&!)($#&'+##$+'&'&+#+)!$'#'*#'&$)$('##%#'+)!*(#&")%#'&
@r8953
AATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAANCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTT
+
'H!1#''?$9'C-4%+/E2=DB.?5B*64>8@%,6&4(00!HH71>=6*8.<52)6:7:*&'!$'G,2E3?3(>@:)/77%:#.C8?!A42E8+93!A1;+,&.2'0G4:"H$'+@6:+G=>(4,2C5*7,>)F;G>72C/&:=H;$BE?F?BG?*>B'4(E(,&,6C*)##8!$59H=3DF$3$CC45G3DDH9+C9-C9#:?5.@?:$3HD;8"H@6515A
@r8954
TGNGCTANANANTNACGCAATACGATAGAAATACAAGGCGATTNAGAAATGTATA
+
)''()*%$*#'*(#++#$&(&('!!)"&#'!+&()"!(%'&%"#('#+*!"$(+'
@r8955
CCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGA
+
0-C9&2"B*(:GC+;?*39A143=C03E4+G&/-"7G>3243#EC
@r8956
GAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCC
+
@55G!3'*5=.-.?2"*#/((A84()20D+0F(%(&.B+;6B44-8H3+A?<C!?':7G)558?)?
@r8957
CCNTNGNCTNNNGANCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGT
+
'(*%!"#%)"$%)$#"+%!%'!%&'&(+"$)$*&$"#$"'$#)+'(!#$+#$!'##!$!')
@r8958
NGTNNGGTTCTTCGTTCCTTAAAGACGCCGTTTAACATGNCGATNGCCAGGCTTAAATGAGTCGTTGTGAATCCCATCAGCNTTACCGTTTCGCGGTGCTTCTTCAGTACGCTAGGGCAAATGT
+
$"#'$"'*%)%+!*&)#&#)'(*)!+')*+)(!)*!)$!"("'&$$(*!%*%)("+$"*!'(&*##%"!'#%''(!%)'&'(+!"$"+')%#"(&$'&)%"$'%'+"*'(!&$$$+)*&#$#%%
@r8959
CGGAGGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCCCCCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTCTTCC
+
/9-E2GFF;=>?&49?2$/"6<G50!/%G;,(:1F2@A'%11>66%A0@<46)/):7'*6H*8E30?;./:F:<E2B@=HG1
@r8960
TTCTCGACGGGCTGCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAANCGGGATATCATCAAA
+
4!8>3@(!&'=3A2:H21(.@,-1!/0A54.+2):A$F>C250(14B!?!)$*E2",AG08#?-490=3D8G?D@C@H4!8/%/%HAED
@r8961
NCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGT
+
!HG.A,"'$>$#6%-A9/F66&'6=EF>H#./0,DA$8:/#6%21A8$HA14B38)?B>?,,!F34F->/6H..;)"18C/G5$@1:$:"0/45%#7!#&D?6&"'"B9"=E+7/,&3-#G&->@?*B06.+!+?:(G
@r8962
GGCCGCGATTGCAGATGTTATCGANGCGTCACCTGACGCACTGAAT
+
.)'>&)*6@#@0)0F!=>67!/902E.>A:<.(A6,9@A"(?4B!@
@r8963
GGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCT
+
AE/<C>C21-=H75%3G(:!1EG-E"1DB6F6ABHC4</<8@BE.0B:&(&%,65,$0!8>2?37<7+%=FA-#+!BF"90H,"79BC?5B'FC0B/B)7(8;:=A47+H4-5?3.0,63)FD7,1)<7&@@&F35;.EFD18F!#5*(?BB3E7,7:;E:*,/?+3%H*4=-/>H0=5%341(:(==+8D3%H.;83-4G=)H,DDA>+:!
@r8964
ACCATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAANCTGTGGNCGTTGATAAGTCGCAGATCAGCCGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCNTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTAGCGCGACAAGTTGCTGCGATTCCCACCAATAAAAAACGCCCGGCGGCAACCG
+
B6(5CD@%E"!%/5?0:&9/4B!B/,;<@$4/GE*$"7GA2A3%;9/,!9$21B2*$#47(=,"/G>E$!E*,%07E8-F=9=.E:<#"73A6->30EA.CA:9),:%?:'2B4188/#F*8;!95B8"7(?H6H2H<);0$6!*E$7BA9#H6-<;F$*.D4,A$.5$0"5'"'F(59?D7*4H@<+36?.0(H4H7<&0A+GA-!H)$0;?7E:<6E&:F@)"+-F8D<4.171-8$D-0,5#$D3/<",2DEDD,3<CE.&D-(G8D52+?$'5!==(FH=.5$4!:H2:07D!=?4!*C69?)(6=
@r8965
GGCTGAAGACCAGCTTNGCGGGAACTGGATGGCAGGCCTAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGG
+
;9(1@25')%21'$A*9!65$<'709*=&B@??C'08E443=&6$E+2(3>/9"#-:7,#>=$3!1CC9C7="DCE,B9*$?1G,7-)E/
@r8966
GCCAGTTAATCCGGAGAGTCAGCGGTGTTCCTGAAAACCGAATCATTTGAACATAACGGTN
+
FAG'8(?84!,B+==B%1;+82B?A&F;&:@".?4-<$<0/83%.B1"EB@.$$",:'/BF
@r8967
TGTTAGGTTTCCGCAGAACACTGCGCCCGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTG
+
($2DH;C8<'!E28"')H,8;81G"-79*0E?0$>"-&?F-=;AG@C7"!4"=CF,"7-B>71B"?H*7<>*1/F$*)%:(40!5>1H98,?<4"-C262(6G14<?(9";E'$/,&?00,/6<8$F::8>!;A
@r8968
ATNTATTNTTCNCCNTGGAAAGCCCTGCCAGCGCNGTCAGTGTCGCATTCTTCGGTTGTNTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGANCATTCC
+
)*!$&%*#(''&*)+%&$")++)&"$!&"*#))'*&($%&()#+&*'*')&'$&%##()$$($'+!&'($"%&"+$!$!'!'+*'(('&!&))*#$*#+%$)+$')(&
@r8969
ACGAGAGGAGCAGAAACAGAAAGACAAACTTAAGATTCGAAAACTNGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTA
+
7<<3/41/,?%GE.7+2&%/:5"*H/.,29;F>$!46%:2&<804)"9#/H1@%)=#&@@H5CD+78B,A!G.'.@*!.05"9;<>/=G*A("G
@r8970
CTCATGCNCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGATAAC
+
'=,9F%3CG2)+#F)<+=/(E!4E7E8;9:D,GA2%;>:9'B?C+#=*'*<7(*.GEC!+@;HCH4.;2%DD0B>4+C<40,C*?1*>15=#?F+C.4C#;>H("9E8+5*;D28*1$(%#@?*""+/)9
@r8971
CGAAGGAAGTGATCACCNGCACGGTGAAAGTCACCAATGT
+
+*"A&6'8?#!@9+=0E"1??H;$14(8>02(/2+1:8.,
@r8972
AGNCCGCNCCNTNANNCNCCANCNNGGNACTCNTNNGGNTNGAGNNCNCCGNCTTNNTC
+
!##$##$!!$""""!!!$""#!"!""!"""$#!"!!#!"##!$#!"$"$$#""#$!!#"
@r8973
GTGGATGGCAACCCCNACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCC
+
@/%#38;&4D3CG2!&*0$$(E<=%B:AD8!)%F;!,-#8=,*?7',:&"'>@6<?+A>+3E"?7>@G6&(4C
@r8974
CGGTGAGGCTCAGATTGCGTCCATCAGCNAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCG
+
E,.,F'%A,4.@*H)F+1CC0F#4)8C>3="6/F%3+AF*F6G'#(,BH)FF9?$>#?6FE#B9:09D/<%./(GC<D3,3-0>D->"/='&
@r8975
TTGATCGTGGTGATATCCGTCAGGCAATCCACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATT
+
31G4G)AD?&@2..>G(.>EAD.5D2&=9"!?(/=9G'8:,';?5">30(%%8#/.F3@)(2'9!-3+.B=5B!.<A+34=&!72$;!*821!A8A?9A5?<0A'6>
@r8976
TCAGTACTTTCAGATAACACATCGAATACGTTGTNCTGNCGCTGACAGTACGCNTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCTACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTT
+
<;9H<5(<$6./*,:@2!F/4('63#9H1,A.G*B0(@%B=A*#F+H;A<9!-+78@:CE="!%<0'!)>).A!5."<+$&6&D+B#8(C39#,2A'$((,CF!H&A@6A416#<,+5<5+4:-F+=0.1,@5#!4*'D<>>('.+,+9+5#">@$/9C&)=??5:'."5E?85;68?!/1A:'C@/.8=<26#48?!$0'%E%<F>?!-3!F>
@r8977
ACGGACAGTGTGGGGGTGTTGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCNGCACAGTNATGACCGGGGAGGATACGTTTCNCTATGAGAGCCTGCGTGGACGTTAT
+
E*1G0:4E<F"!)5:)"(!1@#2')/7EFB;3H5,0C(<*5.!6BDF80-%&*742-H>'4;)<A$<'(4:1GA5*,E?-*-23>3<B+""/.;05;FH><0G605-2(2)
@r8978
GTTTCTGTTGGNACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAAGGAGATTTCCGCTTTTGTGCTGGTTGNACAC
+
+7#(0*<7&3/.A:1'BF9&6G0B(H'.#E1*#8,9@;D2E:HG:;!'7:'61/D8D47C:<<'F96+">"AA33."=%B=29D%F$2;(1(62'G!D.E37"E@H;3.AA!@4&)2?'+EBF%2>)7"H(6C22%C&#A:$)(G%'35,;A93%,3@06
@r8979
CACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTC
+
*+)%##+(#)(!#)%!"'%"'#'$%'&)!)(+##)("+)%)$)((+"&+'"%#%!#'))*($')#'+(+'((*('+*&%%!*"")&"&+(%#&$(#*!#!"$(+&+"!%#(!%)!+
@r8980
CTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTG
+
5G>+D-'ED<&B3C?D458-4+)4<G83B5,47.%,")>9!F'B=&)3*'6==<7(-&@B/17:%G>
@r8981
GAGGNATCCNGCCGCTGGTAATGGTGGGGGCCGTCAGTCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGC
+
*!#*%$'!&+!"##*!%$!"%##$((*++&)%(!#$'%''#*$%))&**%"(+((+*)(&++!))+&!#*+%)"')()"'%!+'(&)*$$)+"($)!"$%"$+!$(!$(($'+$!%#"'#+#($*+%
@r8982
GCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCNCCTCAGA
+
<:F;;=ACD2B95-9=*H)?"8,)!2?>D?(,.'@=6*6*A"#<>@<+A%<9!"&F%$.H"<452.,B?<@,?<8-/#>8"7)>G=5%&F07&=C/)A4#B@=@.&<;
@r8983
NCNNTTNTNNCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGT
+
*#'#'%!)!!++))+$(%#))$**!*'#&"("!&""+++)")%#"('%)$"+(+#'#%(*+%&&)'*''!'*$#)"!*)%$+
@r8984
TTATTAGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTNTTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATNGGATGGAA
+
.9;'=)F;%AE&=8A(>?2%83$D/,1>'(,?)H$':6HC6!G:G8H7!*C6.C*?"#)'4:4->>7G0+1.)@1'E37;GF4:B#',;D*,)470!,%03("G)GB=<8.4@G=-(AB><%1,0"A.-(D<%"&':/!'H!14;@"&5=;'0-CAD7
@r8985
NGGGTNTTATNNAGNCTNTTTTNTACACGAATCAGATCCACGGAGGGATCA
+
&"''(!!#*$!$&('&')&#*+*&(!##)"#!*!+(&%''+%&&&!*'$!(
@r8986
NNCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGA
+
(%C-.C.1--G//=1(CEA*:7D,6!HB9D<;)0&#//8E8=%$!&55<)&5>@%FC5"0(*2C&>/<3F49
@r8987
CTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTT
+
>4F2%4H40E;$+"EC*4;(''3$<F*(*(!GHH4(E8BC96<$5$
@r8988
CAAAACTCGCCATGTACTTTTCATCCCGCTAAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGNGCCATGTAAGCTGACTTTATGGCCTCGAAACNACCGAGCCGGAA
+
:6."C:BG:70*6BA.H.>;''=*!?G=%@'01@2E*2,H9;-$!F+!=%GF1D3<AB$3814+<0GE*<)C.BG;4C&;!C37G)A(%E86)!F4-"7-0+@1=FB$632?"7D:'/%.@'0;(-6.&#7'8.H*C/*.@0C9,E%C;.<AF3)4GH75;F.%<!G#5F5"G;"
@r8989
TATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTT
+
2G.0$B5>E8C;C7H4&):4FE59(A890(%66C-A30./$B#$)@D
@r8990
AGTATCCGTACCATTCAGAACTGGCAGGAACAGGGANTGCCCG
+
0G"H+4E=+0/56E++23#*BDF*@%5$%E"C27$09?</5,"
@r8991
GACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCNTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAAAACGATAATATTCACAACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACNGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGC
+
>H'H545B:!D#%='@#%-F"8)=(H(#9&+4E>4546#=&/8;5>D?!/9C5<:).F<E*33',!'((7)H2=$4"!/<F$88!883$$'3+--/+%340)"()>.,&4EA!@;F#3/2/D"B5@"@)+E&D@D2H;CF(&3%"49H8;5@>"E-%&D@BA;F*,!@:#1'3"',;4EE743FC@@:)17&$@(1H29=<H#GD'0-36#(D!"3<3&(8@%H;;%.<C>G!=..4GH!7?FC83&">#,C,):=FA.%*6H+3?H;2;*'/!?H4H,90/:=%C4D4='G&(D7H9<1$5@>>!6H&A-)=?$'-D%0)$?(""&$467643)8/?F3&;E!<A7,"==.AFBF%34F+,2$<#E,0F/9
@r8992
GCAGTATAAAGCCGCCATGCGTATGCTGCGTGCACAGTTAACCGACGTGGCCAC
+
,.0A$'5D5C$2;G2<E"#!.4?7'138/@"-ADE-"CGF*&A"40#(EB53-4
@r8993
TGACAGACTGCTTTGATGTGCAACCGANGACGACNAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTT
+
71**);2316C):).F4!!F.D!#<??A'''G(,6'$"10--18B204E,$;@<@#712H'-<D,##33>./7>
@r8994
CATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTAAGNTTTTGTGCGCCGCCCTTAATGAAGGCAGGAAGTNTGTGGTTACATCAAAACAATTCCCA
+
:7+=#)AH.#*/53'D(@9'8>C9>0@:A:<"2F6'EG10:?E-/&8&/GG)H'G%+'0..&)@$=H6B>!G#H=E/3/-H<*:E'>91431=8&716/>%";"%*,=7F=,G;2H"%81,?2-
@r8995
ACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTT
+
")9%:@E9@7!F>."H1<1+%?G*<H7C&,7("A<BAE2&E$'69E*+;8
@r8996
AAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCT
+
@7GB)<6679C*>H9::"*$B.HDD"@2<".3(5A="B&8!!/6E1$+"5G5.1E"7F#@'021>/B)8?$;.?5ED,B':$=2"!=6)F/;$"$$90>=::D1F;-)F&;-5,8;!7:=$*7(?5-E2F"+84?B>@'>+255C?9DFD$G%
@r8997
CTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCA
+
G:-%0G!-7D)*G//2CF4!(1("B>%E0$9/;$>A#@@27B
@r8998
GGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCA
+
7.?-)4%#;F3+803H.A$"*&:@$&1D'6*EABC""#59905
@r8999
GGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCGTGACAAGTCCACGTATGACACCCGATCCGGACGATATCGAAGCATACGCNCTGAACGCAAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAA
+
)+$&(%#()'!+)+!+%##)!%+**+)"(#%+!('!##&$$%'+&(&$!"!*$#((*#+")")"(*+"'%*+"$($!+%')"!*'%(#&(($%*')+(#!*"%$!%+&'&$!%$"()%%&*#$*'+&"&"!+((&+)'"*!)&+)+%*$"'+%++%'$''$*
@r9000
TCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACNGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATC
+
C>6-"B6688CE9H+#9-1,5F7:DD9GA>&7=H9#*+B2)A15,'$'#?B2@)3FCDA8>15*.F:2A;8)+:,2CF%")3,+4H")+"0<@502891#E#3,5@3-=H:%?1/$65
@r9001
GATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATNAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGT
+
4.2G6@G:B3@@26'(",3B67AFDH$!5&36B;0")*'-2E2,B>@;1=>5@H83#>:"(>;#A:=%13E=4%'E><C&=-"FF@0&D-0"'&7'88;H+/67;/6.(
@r9002
GCAGTATCTGGCCTCGGTGGNNATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCG
+
B&B+%1G7F-EB'F@.@)./5'4@C4(-@)@):>E"#(!5#1>$./.>)'902$A52EG&F:&<<2?C*12(;C.,G>A>(F(6F$3#=*?&?13H9,1)1=>704?2;A:9.H,>5;*;GF6('HD<5,'1"E,@1
@r9003
TCTANAGCGGTTATANANATNNNNTNTCGNNCNANCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTNT
+
($&)%'##%"%"')'%)$"$%")!(##'$"'%&$$+$"$%""%&'&%*(*'&#$*&$&!$)&$*)#"#)%"++
@r9004
CACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCC
+
,"*'0C%@:36+D.)9>D5&@(%D!F<.>/)!:?9%7&H=:E:B!8&24!''=/B)&G%19;3=,,8=;=5B(&461>B;,+'77GE8,"2
@r9005
GAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGNTACTGGATTAAACAA
+
+G@;35+-4.E?H8007E$D:4;@/B58/HF?&4B10!;/%2*4'+,;%!<,@/E9#!6(C+1BF;B,0!,"/A=2*
@r9006
TTTTGNGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGANATGGTTTTATTTGGTCCAAACATGCCGCCTTGCT
+
D;(.90+2=4")'F/7HE--*.FE>E3("GA@2;%"$10=#)/>FA(/CB&;H%+28=$?2&C)#)?0&%$:+#F6/,*,'%&9G!/9($-565E7H?F)F)#@<(:6/)1$>'A9D$5-$26E5
@r9007
AGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGC
+
)&:'66((#6C4H3<5?9G!:"$,E)+84@(?9#')30>9(7871@
@r9008
GCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGTGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTG
+
)9!75*#1!#37'4'BC2((A1H*!*7!4:+&'.A!A;7D;":F6A3FA(D,>91FC*D?'.CEH<6355?@@+H+/#,,,5$64'4=3
@r9009
TCNGCTCAGGAGGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCC
+
#&!*+$"&'"+'"''%#&&%')+*$#(()*$(&&'()'''+*!&()$&)%&)$$%$)###($+$%"*&)
@r9010
ATNATAACAANGANGGGNCGCTAATACGCTAAAANATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACANATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATT
+
$$#&$"%&)$#))#)+#%"#$+($!)#"!+!'&*#*)'$!)+%%%"(!#%'+#"&$+)!#")&)'"#("&#$'!&((%)*+!+%""+("()!&"!%$*$!#$(***%$%$'"$(#%**&$)%)*%!)+$*(#%&*(&+$#!**(&$+!($$"&
@r9011
TAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGA
+
A#C;>:0*92'64-HE6B#4F;"!%()">E5!$)3#%+C(;7*61G
@r9012
CTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCNAGCGGTGCCGGTGCCCCCTNCNTCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGA
+
A*4)**=EAD=0B>!A"78GD&@7.D&8$-1H15=>.)8#.A*75(158,B#%<+&!";/%FA(3''CD,@)39F'/(4A5BE'$=,;2$FB0)%6-4D;'6+!<3&;H/AG6B@#-?")&D)=2E&&7"3*/$>4(*:11)EA49>1,G,E"5(3:D1D0
@r9013
CNGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGAC
+
&(H:/:,'3AE::B<=3-&BH43"CG%+2!F>FBF4/?@<:G6G7@=HC)(A;#(>*2-$->";;1+G+!-$5+'+H6@8(@
@r9014
TCANGNTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATA
+
?3->*4"$-&31>6H15:)3,;H64#F6B7A$D(2D?:256(3592A;"#=:%:6%E,8<07/+1E/>E!1,9D;B-(G*/(CC$AD#F1:#&%),"1AF-DHF8-@E*<#<8;='8?,4C-6!A/B5,/81">@(
@r9015
GATTCTGCGAACTTCAAAAAGCATCGGGAATTACACCATGNAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCACCAGACGTTTACTGTTCAANACAAAACGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGANTTGGGCAGAAGAAAAC
+
1:!(30C#$!@5-@8652@B-%B&7?H1<G,"-:!4@6.(-B'C3!ACG@*:(0?</5!C#8:9'4=FH19.>/8G+$1=2$$:$(/)4:%?;';@#*28F8'B*.<G/%EA)3A-23C<HCB6*H'/"8>@=3C>#FH7=H'G(HH6)2>F:>9AD9A.6B&2@:%FDB03<9DHH3#*7)A+B-"FD
@r9016
NTCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATAAAAGCGAGATTGCTACTTA
+
"9<2D*:<E:3=AA'ED:!/<@<!%=1#21EGE;>-F.*<<,">?.>F!#00??G8;!4@=
@r9017
GCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCC
+
8C$0&G61H5<#:#H3#G9*>,)50"B#;5!1&'DH?E3@0:7$)61+:'-58B,%>$2!DB*+<-@>BC
@r9018
TTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACNGAAGGTAAAGCGCAGACGGTCAATGTTTGCAGAAGC
+
4=28341B8-*1+;>4%F>D3!3.-52/?BE&127&:F(8!.=1C6"@='BHA))B/",@"=+HG&3'*6H.,37E>(D&@91B.;@8-F)4C-1<"58D-600'9D)F/'(C72E7H$4D1"6>!F,(11$9*$1+$)+7
@r9019
TATGATTTAGCGTGGAAAGATTTGTGTAGNGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGNTTTTNCCTGTA
+
6242(8+H&+$@27C16"+,;(><2@5%/,&5.F6A<F-=7,)D6'%G#=>48@BH;&B5$/+DE!&/5+EE)D3B4A/;#"D6/4#:.2!<-=%!*2@1?+E"3D"B#/B,+8F(+@,>G42+)?<&C(+!G":C1"@#<./;$F1
@r9020
TTGATGGCCTCATCCACAGNCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCC
+
99G@'>6/9E&)!E42C.E-H,<12E8@%,=,>?>8),(1'C2,G8C<3!.$D@&B6=+:<"C#2+.0!4?/*>6;26H&%-1:=(*=>6*DHG)=*,F%($
@r9021
TTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAANACGCTATTCACGCAGTACAGCAAATCCTTCCAG
+
@"G(240?8,H$7#2A*>8+;9BH;#:.7+4;F46((?28G)&*G1:F+8D%$"(2#49,#F0>956%1?=*5@9%!$:$H?F61(DF4+5B&FB.A";1"C
@r9022
TCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGNTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATGTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTT
+
=<)&,92E6336C)00(FG78E"8";E,(CD<(:B0(9;(F;&.=7B*E;7372/&6.(4D.<+>9,0B*$3%5CHB!-%+=A%8:7:'@"(9B0&B6?**$")8?+)AD&-0$$5BG%E)>DF,194%-+?76(/3E6D$H*!&-*:F;<$;/=9,H!G'9CF9H-*?8>%B*/F"*%&&"'#<(3)+/(0/=D1&#)9<"-92/#E<G@6F=35%*260:;",?#*51G#C)8)A%0*B4*AGF5-
@r9023
TGTCGGGGCTGTTGGTGNCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGG
+
:G5-:'$6,@202"-(.#$(A(?)0@14#559:%CG*+'B3,.GA-+-@.4#3
@r9024
GAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTGTAACCTGTCGGATCA
+
&@<9.)F.*3AC?+G06*:*:=G-+9?+DFAB''AD(B("",C)DB930=@;)3G:GCC<
@r9025
GGTCTTNCCTTCGATGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTNTCTGCAAGTCTCTATGAGAAGCAGATAAGCGAT
+
$+%+)'!#"+')(('&**&"!%#(!$"!+((#)")")$&'"*)++%+&$*#'*"$*&&*#))"+!!$""$)('#)!)"#*#))$
@r9026
TCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATG
+
'43')AB,#(%//5<=@/,*<B5%?FG*5!8#;=)6?.3.50*F5+DD.#-612?>+CH=!@5:!(:'6E%<5.!18F));%8(74"
@r9027
TGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATT
+
=.H."C%1.47(9B)$!):#&*/-*.'G)?9"#:G%AA6:
@r9028
NCCTAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATNCAATATGACAATAAAATAATTCCTGAAGTTATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTNAGTTGACTATACAGCCAAGNTTGCAGAAACGACTTTTTTAAAGGACGG
+
+&B8/G=."H.24%//A?%'1;6)'DA*5;<=D--)"E:D.=:=9>"4AF(H-&8;5,7/%<<7CB14HA)"$!H(06-.GH*4/)1<BGFEF";A1)=E.H",)!/H&@A"79%"1:@A0E/?'6,!/(09EE'0(@!89A;;>--+17C#1!-$E3B'&(%/"!DAD8%9396'26.(-B7%3?
@r9029
ATACAGCGCATCGCCGAGNAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGNCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCNTGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCANGTTGTTGCTGTATGCCGGTNTAAACGTTCCGTCCCCGATACCGCTGTATTGCCGCGTCTGCGGGTT
+
FD=4B*BE4>=+!=A&'.=0,G=;+(5+"0C9AD)#+!26-'D:>><?CA':D--),B?B73:4?8)'/8'9#4%C?CHAH;#?>2&>@D7AA562*G%-F%!1C3)3D<:=&!3-95)00.C-F<F'''G?;%,*'C);A18A=,E38>.2,3*="CGD(1>D//F>!92#:!A$A>.2F8,#5.<!E=8%'%)!D#?"4G%!F0/$3G;$C4%!E0"&678-7(+<<;C<,2C;>@84&7#B);ED,&7"D%0%F:38>,G17>->)18DA/&AB1=>($GD..H,:.5E7;BAE/A
@r9030
GTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCA
+
<B?G'>-8$D+F8&6)2G.?>G0((&;+E+*EB,-0$/&(1-5G
@r9031
CTGCAAATACCTTCCAACGGAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTNTGGGATATCCGGTGGCTAAGACGNCGTGCGANGAAAACAAGGTTACTGACCAAAATCGAAGTTA
+
6?;)+(E46$#(GD/-<GG2$0*#C73;$-H'F/&&26?7(8B4/C-'?1#1&98G$4;!?/5B==1/'?),6;G&1(G,!3FH#&&DG(G%1,2#@2#%#F,,C0/.<8959:@H@&(GD7(#(%2A"0#12<@,>DA"F8H>&7D@E@1&-"80/4
@r9032
CATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTT
+
3*.F29?9.G&/+9(*$8#.<3$?F+:76/5=5,"4AH<2(@6:E'#9CH8
@r9033
GCGCTATTACGAAAAAATTGAATTTGGCAGCAAATACCGAAATATTTGGG
+
+$)&"%)&!&%)*&"&)*%%!#!('%+"%'#%!&*!)!$&%$&&#+*(++
@r9034
GCCGCATTGCANTTTCGTCACTGGCAGTGGTCGTCTCTTTCAT
+
!)+"!(+($'+)*'&%%**!""#(+")"%)$&%(%'**&!!*'
@r9035
GGTNNCNGACATGACCCGCAAGGGTGCCCGTGATGAANTTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTNGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCCNCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCANCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAG
+
&((&$""&&'(#*&+$""#&")!"%"'+*!!++'))&)("'"%($+*+&&$%!!$)$!%##"')#*(*!*%*!'%##*#&#&#***)(**%(%&(&+*!"$%%!'!#))&'&!%"'&##)"&%)"'+'(+(!$$%'&$%)&""+'((!))&"&'!+(!%)'$+#)$$"*$*%("*(#%$(%)!$+)'*"*%!$+')(&)#!)$)()$!$(&)*"%*#"
@r9036
ANGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGG
+
'&)"(+'#"&%%"!)'&"#)#(!&%!+)''!&)'"#!!*&
@r9037
CTGTTCNATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTNTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTNTTATCCCGGTGCTTTTTGCCATACCACG
+
G>=)F;ED=;6!&,-,(&;=,G3/C5%)+H&H3C='-F(B(+C#4;%7$>)"?!>99F%,*F#2!61>CDA/*;B!!6"==F>>#*,1+!7:B@/")165*(A9*"@+2CB!6+=6-;,#&5&?H:-0)3F-C@7&;33.0F1<H8@,#*4;GE;C"&,G>D79>?*
@r9038
TCGCTCCCGNGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTG
+
-C-=><0-7>5'"!@?'G75$$"C/+.%5!52>.B9,A7%<D/;)G/$
@r9039
NAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCANCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGCGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTC
+
$%*3'#23,4?>*C9B#.C2"*+&,%;#&(C6-&G5+&B-B)FB2.74/CA)A+*,'#&35$2,2)A+:A1*%@%?4"8'@85"89$0-/"#;6'A(&76&1(C??'&-:9)7&6248'3/,3&$=E.9#B4&#B($/;B=+F;B
@r9040
CCAGGAACTATTGAGTACGAACGCCNTCGACTTACGCGTGCGCAG
+
""?&2,C.43;G<+DG$*(4$3CD51%@;A8)F:0:>%4E.9$7(
@r9041
AGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGAATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCANAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATGCATTAGTAATAGTTACGCTGCGGN
+
3<@;E@F00*.3%/+'=1A%-617/)<'==D+%%#B/(4&;>%@0?D0%E@8$#5BF+'/(-<)=6#'C?5C:C'3!F8=&G(+<!=9=(6%2-#$2&%%F+=A"*7;B?5)1$!'&4=.'G5@D'F&?G%6)G8<9+$'85-2>(:')!+1:;6+8<H0$AA0BF13E?;#)9G2834?=>@"--?+;7%*4;<25+!*E.,F(.5(&-:H4AF(/A5("4@8DC#?B:#<+<=5#'>77%%,&1/BD<=A7CB''BEH,"3<;/02$
@r9042
CAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGC
+
5=C!6@7,C$!<+4&/)):388DHB4.1EH768"<2AEH)@F/-1GE7G5$7;:$.H9.8D
@r9043
GATTCGTGGAGGCCGTCGGTCGGGCGAGCGATNATGCGNAAGGT
+
"C(E)2GF-H8.-FG@-;=G>?H?$9@021C0@0"EG.21DEF,
@r9044
ACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGG
+
7,.5E?$'-5-6.+H=4@)6?."/&<&<(.?E5,G<(-!G3;E
@r9045
GTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCGGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAA
+
FB$@F!83.6H,6D1/&64.'9@H&=(@??-6&$783.!>$1>4",0*.@A0*93E:"36@/+=%(9#@.G:(".+E
@r9046
TCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATC
+
*D6H87'B<)%F'1H814$3?C/3;?0@8:0-#A>9,88FEB2:?8A(&F9H"/$33<5<E0+6>@>G-EG
@r9047
TCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCNTAAGTCGATGGCGTTCGTACTCAATAGTTC
+
D!7B:A*B,?D=*!G-A<7:F:74!G(*:3A<>3,.#1+3'8@%#>G!9*F626,F10?7$0/16(>&C)@1,85C(..71&
@r9048
TGCGGCCANNTAGNNNGNAGTNTANNCNNNCTCNNGNNNTGNGCNNNANNNAACTNNNTNGNNNNNGTGNAGCNGANCTTCCCNNNCNAGNNGNNNNNGATTNANCNGNNATNNNTACNCNTCNNGNGNANNNCTTTNATNNANCNANNNCNNNNNNGTNTNNTGN
+
$!"#!$#!!#"$!##!#"$$#"!!"$"#!""$$!"$#!$#!$"##!#"$!"#$$$!!#$!!"#!!!###$###!#"####$!$!!!$"$$!!"!!#$"$"$#!"#$"$""#!###!###"#$#$""#$!#$#"$"##!##"$$$$#$!##!!!!$"$"#!!!#""#
@r9049
GACAGGAGAATNCAGATNGATGCACAAACNCGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACC
+
@"+?9!3C1617.;G..=1D=66"4=+2<(3!A(23>B."-F7:A35CD,3A6=<8631?&?*$*,H-<9:."ED8-4&'@,)8!%H+E8!,9EG-')36<-;:8>?6@E9>)=54<B
@r9050
GGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATNATCCGGCNCTGGNGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACTATGAA
+
6>:G#F53!E56@'?@)GE+EFB$=?@C=)8856?<)A#@A"97*AC-$3$$C(&:A;%15*>.E)2/6G.%;@+E24,G>>74618+=+*;C--H(H112;A(='E4?%'"=:$A6.15E7:B&DBG?;?$?B5,%15$F43+
@r9051
TGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTTTGGTGATCA
+
8-1&@C#.)(/%7?GB+C+D&-27)=.A4/@1;"3-(A%)AF!@."9C#E<?B?(!F$0*!G'+E(9,-+?G7H)6DF#+&8/-<#8=1$'6E)8#?FC2!8'CE;269"A4@+<23C4$F4+B879%#9$D
@r9052
ACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGANGAAAACATGCCACACATGAGGAATACCGA
+
&9.D=E>$?7907@5A5&H?:"B9A63$D)F=CC7A/-#@H1+/HA+6+<1%,$&0++89/$8)=61GDCD=/.4EC8&+7@GD@:.<%>-+8EGF@+0A"E0=>8@C>-10A'F%6;F<"<0?')</,3/:0(&/?C3"6>C6#('%CC&B&H!8C0&'%G<>1H1.37=-*#2.(0@=)0;1B>>>F5499:A>=,<5-24;H2H5-EB7;AGD!2,B%$2C":D%##<*F:6<A,E6.G""4:.831D:1<
@r9053
TGCGCTTNTNANNNGNNCNCNCGNCCNNNCNNCNAGNNTTNNCGCNTNCTGCAAGGNNANCAAGNNGTNNNCTACNNNCCNCCCTTTNTTNNNANTCNAAANNAGTNNNTNTGANTAANNNCTNANTCNTNNTNNTNTACGNGTTGTNTGNTTCTNAANCNNGNGANNATTAGCANCGNNAANNNNNCGANCCGCNCANNNANNNNTATGNGNNAAGGNNACNCNNNNANTNGNNANNTTNCNGGTNNGNNNANNCNGNGNNCNGCGNTTNCAAGGNNGNANCGACNGGCTNNC
+
$"#""$$$$"$$#$#!!"#$!!$##$"$!!$"$!#"!"#"#!!#$!!$$"!!"$!$#"$!!!!""$"!!"$$"!"!!!""##"$$!$#"#"""!""!!#"$#""!$#!"$""!"""""!#!""#$##"#$"!"!!##!"##!!!"""####"!$!!!$"#""!!$"$!""##"!$!!!$"###"#!!!"#"#"#!!#"!##$!$#!"$#!""!#""$#!!"##$"!$"##!"$#!"!$!$#$#!###"!!"!####!#!!!##!#!"$"#!$#$!#$$$!"#$!!"#$$$$#$#
@r9054
NCTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTNATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTT
+
*FD-70=G9!7/7:>D-)"%*H.&=CG/'0$6/8=*%AB-B@6.&5;3"?5@:GH!2B*%:#'$$&%36.11&H0?A#7.;*"B%C?82:&6740&D,@2$/81>&"1E3AE,-$3:$(4CD(#:8)&B@-F,A*G1,;,0!5'B$(C)1<&G0&'-98+@@9G&&)
@r9055
NGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTNACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGA
+
!"?H&1E8D..62/=7:E9*"4B&&?B0;=*33@E.@/51("DB!22%2,6G9&#C;%1(6.H;3%92+>=5G1&;=.0$8#1E5/F!>>8<="<4%@6)G+"7F?+4<3(D@!='#9@&9.#+5C?+,,%/!#@5C-8$<2@1H;)#>5A?871.B0>6'('143(D#><1"
@r9056
CAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCCGGGTCGGGAGTCATACGTGGACTTGTCACGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCC
+
8.G:<E-2$1'>!,EF2'*2*HG&.70/=7EF.2AB3GH$$+G>6F<?*9+48:AC.*37>:7.0!'6+B"/'"2:-&C=:23.;0H=BG4A'.203H"+)4'&7!!(H..00<>E:-6D).;=?"D6<4AD!?/*0A$@1
@r9057
ATCACGCTCACATGATGTCCACGCAGGCTCTCATAGTGAAACGTANCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCNCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGCCAAAGACAGCCGGCAATACACACATTACGCATCGTTC
+
@(?.A';>*&'C=)F">=H;#H@3>8+860,/@E(/G5&D-,*B:2+"BA1/$&@2?1@*5/88=6*=G?1(6&;3><F8?@%G,-),:>"!#1+E,<99.,9:5$36691-;2&8:*$BA$'8F%-'.;*>0914*&:B*3>;#7$.$H0%E7@0./F!F&.5>B!&-H%4"+GF!($H#$)&+CG=7:BGCE>2&7HB?34?#1D))')-$,6>7,>*$';1-=++A5-8C?<AE2A=G%3'?/<;73,"%)#/3%;/0B2C:,48F$9%+9*%G:A"E-6;,)F0@30>/D/?/2D<&6F%8A%)18&%&BA@''8#'EH
@r9058
NTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGNAGGCGGCGCAACGTCGCCAGCTGTCTGCA
+
!<3D?HHBFC&='&!36*<;/#H#(@=6&E9#H/&$)69.=<5$"3D/+D;>->=DA16":,3B
@r9059
NTGGTCGACANCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGGAGCTCCTTGCCGAGATGGGATTCNGTTATCTTGC
+
#+("!!!)&(#)")"("#*$)%*%")'$!#&*&#('#)#)(*#%$"+%')'$&&+#+'#&%**%**$)#$*&'(!)!#!&%&%!&%"$!)!)%('&'$)'!$%$"%*!%'++$!+#&)"*%&++'$+&('#*$*"!#"*($#$
@r9060
CTNAAGTTTTNCGCCNCNNNTGAGCGNTNNNNCNNNCGCNNANNNT
+
$"!$$!"!$$"!""$$$$$$!!"$$"!!!#!!$$!"#!!""#!""!
@r9061
CATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGC
+
-:142'!1EC4*#:1@D-,3B=AG?9''<6*BC=%&'B8H2@8>;H#13>
@r9062
TTCCGNNACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGNTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGNGGATTCAAATCCCTCCGG
+
EE"-"4:%C>8*B5F*?93E8G/*H:>D!*A7D:GE=2(3<%:5G.$G28&<*F5G-;>H5,+5&84/$#)"<7!GB%743(-A*&+-)@29(218A?E?#&$G5>22(#E!F%..,!>:<F$@5&32>CA-'G<678C.6&;FG(;F</B,/C(D?+9-+&?34?G?@&EF#>#0GG,'2&=,;<4F83*./<8A7%?,&->3*;7'.(;A@G(@2H)43
@r9063
CCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAANATAACGTNCTCCACC
+
'3>+C4%2#>$$8@"5D95-68+:8';,-"%D%,,F(E>"/FGA6#+?GE:G()=72/,86<>-
@r9064
AGTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAG
+
%$2:1HG/5A1*('&87E,6F#;F<0"2#D'&!,3"$."?90)>2(!2?5(?.H/4A
@r9065
GCCGGCAGCCTGTTGCAGACGGGCGATAATGNCCTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGC
+
*)&&+$$'!!*(++*+#&(+$('(""))'!(!)(#&*"!&!'$)&%%(*+*)$'#+')!*"#%+!$**("#)$
@r9066
GATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACG
+
'F88<BA?3D13B4,7HAG6H7:5#::*='#00,C$9G!31G@1A4:H9>&A'#77G&:!6+B8$1.+0%#;(3?3<*.C+.398@E:%H.&G*?>+26=532D20>2&G-5?/7""7&)0!
@r9067
GGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCANAAACAGGCTGTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACATACTCATACATACCAGACAGCCGGTACACCACGTT
+
6+$7H0;1>95'/#=&<::0,B.D/B6C4:?,3=35G4)-@<5?+%+!(%$#.B='*2"4C4F#G100H32:*<*6CDF>,*643:B4&%,/H;E+%@*H5!"A;E?-F<E(*5,E84-81"@!792E)E4H-(>*4)=-74)#&;6"2?**$4(=E>5/47$+'765"%C)B:F%5C)0D/A8"$*D4/$/7
@r9068
CGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCNATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCANCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCANATGTCATAGACGTTTTTATCCGGAAACT
+
)+!#(*+&!*#)($)%'#''#%)(&'&!+$&(#*&$&')%!"$!##+*%"%#)$($&)+*!!$%"(#'+'#!(*&&#())!%$%+%++*'!"&%()+&%#&$%(("!*!$(*%')&%)%(+$*()$%"((()#)')"))"!$*&#**%)$((#"*"&*'%+!&&')#!*)''$!!'%$%&+($'($#"$'!
@r9069
CCAACGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTT
+
GD@9-,>5"7D%96C$(C/8:'8HG-A7G7%0:66<)"C;!?9+6;(796B=:
@r9070
GCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACNGTGTCCGGAAAAGC
+
C.*=*G3$H/F-)58G&G0:C!'4:$G>%2$BA(-%5D1(&(:84<H-!&%ED=%182.+/@1-,D(,F;(35;/.F=C5B829?(D>@#2>4?%="C$&7+4FC3
@r9071
AAGGNTGTGCAGATCCGGTGTCTTGTCTCTATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTA
+
**#)$'+*&&%+!#*$+)#&'*#*!)+%%%"&)$)$%($)+$*+)+'%*$#))$+!&&!)+$$'($*&
@r9072
CTTCCCTACGNGNANGNCNTNGATNCACTCCCCGCCGCCGCTGTTTTTGCGTCTNCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCANATGACCTGNCATTCGTCTCGGANG
+
%$"%)))"$%!(")'**%!#!()"!(+&"((!%&$##"#((%#!#!+!++#&($()(&'"!%"($'))!#))!!'#"#"")'$'!$!'#+"("+%**!%#'%&)#+&'''*$'#"
@r9073
CATCGCCGCCGAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGG
+
&-,-8)<98@?A=H2",0=%0A<1C#02&7$3"@0G7:)55**#2;)6%1.G)=8:!B"#6,6637#+8,/;H.%2"?.'@'-2=.;&.<16?72:;*43%;9%.!%-)1?@
@r9074
ATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCGCGCCGGGCGTGTCCATATCGAGCAGAATGCCNTCCACCATCCGATCGCTGGCAGCCTGTNGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGANTACG
+
E=#@=FC>0@,!A>";95*0@,!8;,&-G#A1:#"B>?,022(&5;*0";6ED:C+')=5)5"14'05#(9/*E'?7?CG#$(7H-73%79;BC6#?,#!,34G;%**71*7CEA$/6+=0=5*G@8:G9%D#;48>>=GH0"2!#"''>.(C087!G!'
@r9075
NCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTT
+
"0F('87)+$6=;9(?&&=+-1$:9C208'!5H!"H,B(1
@r9076
TCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCNAGTGCC
+
2%B"D/G,78BEC@6$+3.:$"EB1*::F!F,,8'7+4+!$+7$4
@r9077
GCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGA
+
A4">1#8&(51C5;;:(G3:<=3H&03F7E)7E,HC;>,''#ECF%=)"H$,/9(A")%B(>F#299>3%,5)1=D63($&F)1E"+?>:,"0E&B1F6&#
@r9078
ANCATCANCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAAAGTCCGAGACNAAT
+
*")$%&*&#'+#"')$%'((+')+*!"'((*%*#)#$'!"')#&#(*%*(*(&"+&#)!!!(&)+$)''"%!!+###'%")$'!!
@r9079
TGACTGAACTGACTCAGGTTGGCAGGGATGATCTGGCAAAAAATTCCGTTGC
+
+"""!%(&%!)"(&$'&%%$!)#+"$%*$#%%(((%)&%#%")&%&%)%%+"
@r9080
GTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCANCTATTGCCTCTCGGANTGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGCGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCC
+
(0#,16*&E<A6,@8<.$!'E$B9:5<HF)(:$56E&#$:3$4)8B#@$H<9+&2B:5675>%4-5%3,#.-;*($11&*21.;AAGD1?>'"'(?,?9.'99#@('##%<@-/!H9@,:!%?C-123@D85F"4$--9?BG+E(./#(4B33G71495<@(AEH>-3BF@5?3?A?<3B@82D<#:#'#7;+%A2E2"0@"@/31C.!*4'1+F7C
@r9081
CGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAAGAGCAAGTGTATGAAGGGCAAAGAGG
+
E@1<+:E+14;86B03&"%)>0G.-+*#&H@H@F/3G"H?)AGG.)'!)*8HF=#;(0--F@!F1>E%E6$.11B.%B%A74)>45*'/!38*,%>#
@r9082
TCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCGGCCTTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGC
+
F-A.6G'@,"&)AB':;2#'!F2E:EG#F?0&(<)';*&2*C.2%*-)&16>*'**:9:9<$=%.-!F5)#!6+D<=7F(>7@:/6F-9.3'B&8!4#4$23F+C3;A-A*F&%&
@r9083
NCNGAGCTGANANTGNTCGCTGAATATCACAAACANATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGNGCACATGGTACAGCANGCCTGGCNAACGCGGCAGTT
+
!"#'$"((&)(&*#%%&!+$%&'&"*$*&&!$"&!'')%&!!&$!"+%&"(*!"(""')%#"!!&"$'!(#%*"%+&"*$#!'!%)%&%"$!*)$$&&+*'%+&#("$&&'!
@r9084
TCTGGGCTTAAAAGCANAAGTCCAACCCAGATAACGATCAT
+
:3H&0/D*EE<!ADC*<#.H.8A.132=,H-"&%F/E>'!:
@r9085
TTCTGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAA
+
CE:F6&2D!:"H0*B'-+3.<#B,-,8B:.A!F"AH$/B<6!$@.$,C)G1262*'@H<)A2
@r9086
AAGTGCCGCAGCCGCNGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCAAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAAT
+
@(0A&">GG?A3!"B9D8>5.G2-719/'G?A4<2#3?E,D&B@@2%+4:')4H382"@%5-7-9)&%GD)*9-8BB$,B>$,@1CE6&/(;%=*;&9$)45$68H-9>33-<8B+/!3C'FA:'&->-57@9/H><EB*GC.B<7,092E.@9E18$D14FD:E1B@8>41;?&:68,E<45/7=%@
@r9087
ACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATNA
+
B&3F':$B!D5;A9*C1<$)*:+G&2A2786F2B<>A4)C&F3E,%5#:=&!1.07B<,"7B3<*G9:4<%
@r9088
TACTCAGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCNCCTTTAT
+
#(*))&")+)#)#&%"!)*$$%'$#+!#"&+$*('##*%)$%')"""+!"'&&#*&&('"$%))"+%$
@r9089
GCACGGACAGGCCGGTATATGCCGACACCTTCNGCGCAAACATCTGGCGGGTTGCGTCC
+
F<;$=02;5?$33=)E6-EB:(--/6E"'EA:<20)9==;45?EHFF6%.?@"F3E:98
@r9090
CGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGC
+
0!'8D#(*DB(A)7?)/9@<H+(;,43C!C-0E:?:A=C)&-4C!54H:%816G03:2'F8!D12-59D;5
@r9091
AAAGCGGATTCGCGNAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACNTTTCACCGNCCTTGTAGGATTTGGTACAGGCATAGCGTCCTCACAT
+
=+G)97D36E#-2?+,;%,F!7.G9%8*::1)/&<!3F'8:@H@!A>H-0"#9+6H56%3<8#%/G6?@B=432+1;G0=/B:(>0(/05@=%(:A>1!D#;34%-!
@r9092
NNGATACAGGCCTNGCTTCCGGCAATACTCGTGAACCATATCAACCAGCTCGCTGACGTTTGGCAGTC
+
%$#+'$+'(!!**%''!(#!#""&$%)#*$+**)**'&"'&*(++)$+")'#$&#'#$))++!%"""*
@r9093
ATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAANACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCA
+
DC7,9!-+.=##3:(CA<1=($-A/%>@$?'#7<$A2B&'&AA>D;()=6H%&+2>@9%B3.-0<B"=:%C%.@(3F)C)%#G?356:,B3F,1+(9(0EBGA-547A7('"2&4+.1B">*ED%/7>;9/+9-9&D%B&>"#
@r9094
GACAAAAGCGGAAATNTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAAGAAGCAGTAGACGAAATCGAATCAAACCATAA
+
&+#'#$++&+&$)+#*%'$++!#++%$#(&#++")"&'%)))!#$!+$+)+%#$$$%($)'('!(*"%(!$&)%%+%!%+#(*#$'*'&
@r9095
CCGGATATCCTGCATCAGTTCACCACCTGTTCATACTCTGCGCTGAACTCAACAC
+
3=?-GC,F@!2!*:A*!5<BDBE'!5>@>0C$6A#%'6G>&F;;!-/@$/G76:&
@r9096
CGGCGACATACGGAAATAGCCTCCGGCTCACCGGNGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCAAATCGCCGGGCGTGC
+
:HH0/D07-2+<A,A+')E9:6,?0$+):CE:59.#,295,B,%&H<!3/03<//2;)6>?8/H,FA7'8=6G<G1#G1DG/'7GH=)+35"'729;G4-?(/1FEC89@'-%'3<#3F:>&8
@r9097
AATGTTTCACATCGATGATTTCANTGAATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGNTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGNTCGCGGC
+
D>5D78<AEF$<:4(&<5,/'F5*2A%HDF;ECE3BE/%@(/=35G9#GC77"0?C#HE:H/E4'3;A/+8&/@>7("#-8.H2=F,C*67';*&C0'A1#$/)C("&&&).(
@r9098
TGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCCGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTCTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGA
+
%76:<+D@D,*&*7'+@=>39'D*>3,)&A0/AAB<F,9@"#;)8A1-9*#-'<>0!.'$?;*2/>FG=5&%-3/'F?19BBA9H69(;:-H)#-:H,3!&,G."&A+@HD?1E$.DG:,-G3")3/1ABA##F7*H*H+);;?.*.G:E%3/4%@.#
@r9099
GCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTG
+
9"#%&;3@B@&29A3-1A@:"<2G3H/7;'FFCFD=EE)-.F00/*6%0A<
@r9100
TTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTCTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATAT
+
-B>F,@':&27#$0GBA$@*!*5;.(D"F"&@&4%$673A%D:?#735/"&G0*/5FB)9#"(*H64HHE$%3%@@9!55!FA=#C=3/8+,.?+?D69BD<)@BD27@194F?C,".3;(/CG<A-'83D)'%>#21/,415F><7'616755'*"&205B4,E<G5BA-@"H!!HBH'C471&+@?'5=1#?'
@r9101
CCCTGTNTNCTCACGAGCGATGTNAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACANGAGGTNGCCCCGTATTCAGTGTCGTTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACACAATATACCTGCGTCATAATTGA
+
(!()*($%")(("*()*)&+*+#"!&('#)#(!*+(#"('))"*!*+"+&"#!&)!'!#*%)*'+(&*'$+%"$))++$!('#%+%$%#$+$$'"#%&+)##+$&$+*"%()('+()"(%%*"%+#'&$&)#+!")"(&$+"$!($''**)&)')+#)($%&'+)%#$'**%$(%$+%%'($%$)!%%($%%*")"&("!#)(&
@r9102
GCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTC
+
)>G&9E@FH>=#,;$4..HG96<)2G8;<#)8?;!+B$)'/G7&=+!"5
@r9103
CTTTACCCTTCATCACTAAAGGNCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTNCTGGCGGCAAATGAGNAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGT
+
;D1B&F$ED#8'7=?7'9B+H==0!(B'3EB594<4#=%97F!)>AH-0)5/?/H0,G-&"-A3%),")&$C,<)0G@;7>87D68==<%B'E6C9.0<(+B606@,4?8(A)H,,57:05)(7#'+3-GC2G$19B8""E%
@r9104
TNGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCNGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGGCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATG
+
($;F4=!5*;H02C)$%>B*5?##+18?0E!?1'H/$#?2B?1'-+%C01#%-G633+F*3#90+8,$3E2+=63%&.(!,<D)G&'*4AA;,D'GH21-=EC3-!,)-=F&+!'@%-(>@)GEB6>#.!$C(!7CH*7&
@r9105
ATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACNCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACANCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTC
+
(E8?@89!1%C(6"83',,":54@1GB"<&%>?(>#F$H$74<7C,:):(H/03$(+F@$=)/=H++';%E/@&.E4.1>,7@>1)11//(9:;,7!@'''"'&6F<9A$7FE!/6D@/<85*@?@B1E;6;H!96AF2&4-B(.A+8(0@#)CG.8,@=0E$0-ED3>0A9E-;?
@r9106
CTCCGGGGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATAT
+
=FF;4&2<:.)5C6C6//%&<3=1,@1+/#&>>1!2"(?D>H6.$>@C#'(;,D2=7*7,5B6%/$6E=/;8;C:C42;+$0-=</74E0>8+6'(,/>!0!E-1H:)(.C:.4(7HCCG"F!F617G9($/@"$&%72,DF+<'#/5/,4A1H;5;"H"F6GH-A6C!+(2$FD,A
@r9107
AGGCCTGCCACAGCACCNGTTTGAATCGCTATGCATCGATCATTTGCAACGCCNC
+
+(4G82@H)(>.@3"+7F'F=8A)##7E.&1);-!>GA?E@0C:C&'0:#0"C/6
@r9108
ATGGCCCTTCGGGGCCATTTGTTTCTCTGTNGAGGAGTCCNTGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTNGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGNGCTGAAAGAGGAGCTTGATGACACGGATGAAGCTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATG
+
2"<+0'(&#7:H78=7-?4$5<E36'H519'*1(%D<$F(#)*HF34567)"$74.*689@&)&'")=E)+>F@DB@4.02%957&BC3430?=E<70B,/@79/>A@A7/@(1.@46.@)))(H1$&AF$00$D6!&8/5E:<A$A/6@A:;;AD)88*@*.&%017.#2HA<95B>6(&<93/!>#C):)C8B4@F(E63!@(DG8%?@B0-"AB?H)277<FB5(?()64=@2
@r9109
ATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGA
+
.,B,:",9'G?)<%45'8)7F*$=,=79H)5+F!'E$E!3/GG&5AE:B">&,"!$>#9>.;$*2%=8809$9.?.0FH""B24+/3)==>-GCCH>1#*F@2F%D+@="%1B2@"H3@)>
@r9110
ACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTC
+
@;$-2.)%6C?$8:<3#-6=,;A>F*<"+>GH88;?EH:'@'>G0E?C(
@r9111
AGGANTCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATNAGACTCCGC
+
&'!*!!%+$!'(#$()'()*&($!!#**'!(%)+!#'$+%++#%#)!+"#&%+#!!+#+#!("(%!(!$+#'"&'(*%"*("'&
@r9112
NNNATCTTTCAGCGCCGTGTTCNGTTNTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAG
+
!!!!'+&)&(+*&*#*$)''$("%%"*$++#$"&#(&!+($((+(("!&'$)'$!%*&')+%+%#+"*#('&!%&("%"%)'!"!!($'&+((#)&+($(&$"))
@r9113
ATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACAACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAG
+
,1$<H:H5$=1:?GG7?3G%F;@,1)D.':$82ABHBC#78F:DCF5,)(3.0-G.CG4=*2G$<80,+33C?-'B62GB=3+#!47=H90>!.9>?
@r9114
CGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTT
+
*E4>2$>E4"C*"+"F?<209!%>!3@%5"B%+C0?3F4,G$'!+2.?&F
@r9115
TATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTT
+
@HAFB96HD=*5<:-/.E&HE4>$A69,"GDB@+E@"?@&EF80!
@r9116
TCCGGAAAAGCCTCGACGAACTGGTATCCCAGGTGGCCTCAACGAACAGTTCACCGTN
+
HHG2;$?(3%+<0;/;'&8B-/;:(?E'+'C;;<;*C=48A:,/EB$E8.1(?0G=81
@r9117
TANCCTCGCTTTACCCNGTTGGATTACGGGCAAATCCCCCCGGTTAAC
+
"("('&)%'(#*%)&'##$)!#%+!#(&'#)$#)+%%($'#&*+%$"!
@r9118
NNNNGTNGNCCAAATNGTTGNNNNTCCCCGTAAAGGCAGATGCGCGNCATG
+
%')!'#'&"*$$%$%!))($!#&"%+!&(#%*)""+"+)$+&$'$'!*"$"
@r9119
TGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGANTTATCGAGTCAAGAATCCCAAAGGGANATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTNCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACAAAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTT
+
)'+8C.1>=<3+@AG2%=?@)!)E>A2C?49C2?$%+A6D<D!2F/B(/0+'(1;$3&,C9!E"353):69D89GD#8?">E126(?/C3E*?*8+2!:D711A:6A".1A=?H@!3!=E7=-H.*B9?0<'!%B9-'$ED$@)805+G?1/?*GB#B&G+F=&;">,?A(=@$&E=%%<HE$''C)4+C,&*?<A;&(6H:5%(-HG':C:0)=3E%80>0AF&=(0'05*),',C=3H-BA&@
@r9120
TTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCG
+
<>7E:!;6$(<<>D"/1!<?<"D4-"',%@@#GF/%)FF-!6*6<6563G7:4#B!<2+=>-71+2>@=.":$=>G*8?#H/E?8;=)1*H?'-D@7C'(,6@0,H?D5360=890;?@)*=7=G0!D9293B1;*+06@'$!0:+;%*>*8=C
@r9121
CGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATG
+
-G0.2$1EE+:F:*:0GA0.9G+77-+(#=/H1G>29**<8B%?-+7
@r9122
TGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCG
+
408A%#"',B@2)C-F&AH==34/&;.7&FG.91)(?@/@3!"C538-:>E0?C1($-'8%(/'DA?)%,;1?)<:=71%+57/;C<&AAD?AF+&=AB!G8;7A#H?;-$
@r9123
GTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCGAGAGACACCGTATGTTCTATACATGAAATTACAACATCAGGGTAACTCATAGAAATGGTGCTANTAAGCATATTTTTTACA
+
)+'+'%"*!!(+'#)*%%+('")''(++&)'+(')'+##*"+&*!*$%**"*#)*())+*%$%$**#%#++!%'&&#&)&'!*$""%*)#$"++!)&%!*"(!'+*'!*&&+*#'''%("$"%"'%)'%))"$#$*!&!"*%)(#"$)#(&)*)$%&&+'&!$!!+$$)&
@r9124
CACTGAGATCCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTT
+
,GC1>(=*:?.+E&$>@9G/;09$3E2G<-%/+<5#CE#;<?<)&89@/,<24#?@1!F*>3E73+D*=,-86FC,:$/,*05B3&:372#DAA6B*$*A82'0%F0=6&
@r9125
AGTCNGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCNAAATGGTCATCACAGTATTTGGTGAAGNGAACGAGTTTTAATCTGTCAGTGCAGAACGCGNCNCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGNC
+
)0B)<0:4+81D3H9)9'H(@/5(%-1;70'8;79-(9#"BF#7D:H19E/&2/:'627>()-=H>$@&29!(6!!)H9D4*)EH&1!&G<7=+7A)2:&B5*&50A=)%86EB@?(0+%A@FB=??F$*A73G<2!*9/'C'<H#)G1>8"'-#D?8("%04A&.5D&"19*E=2,:.>1)%C%0+#$#8G@/><?27"B*DG;%'F#
@r9126
ANNCATTATTTGATTTCAGTTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATNGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGA
+
&##HCFA,/*AD!;*G;?D%>*";2G3-E"8#7F,3!E):-#%0CBG/A@G<0&0;0-<6+F@!'G$##DCH);,?A)#&'%"0297381<'D&!E"*4&F9DG*<1+9#7B&F%;9GD3GA0(B,?4+D7D>8D5B@=&31<7(>@8'F(H89<+*E&$B)*D$2.EF@4+5E+"*0;6F4'G+623!*@8&0H*'!8%(H@;4?=&=9#D&5@#+/..0(48)5"DF%0ED=+'7HG-BG4+A13FED(8-'
@r9127
GACGTAGNCGNCTTCTNTTCTTTCACGACTTCCCCACACCCAGCATG
+
#''*%(*!"'!##*&(%+"#!!++!+!'$+#$#&!'*''$)('(%%$
@r9128
NAGCGNNTGCTCAGAAATTTAAGTTTGATCCGCTGTTTCTGCG
+
&'&($$#$(!$+'+%)#"&*%**)+)'*+$%!#"%$#%'%)(!
@r9129
ATCCGGATATTCAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTT
+
95/5(HHGDEEH1C%H=4%*$57+<#92*.&<1E5+(5</2+%+1!CCG81"!'4*'<-A)/3#D5=!$$<&<E+HC9E#=<39"/'G/H05+/>#5:G&3"465F&3H56>5'%F/BDB%4'.?3$;%F<0G#5;3@&#C!:B,%H'+D):C&".9?9E:?;9C
@r9130
GCNNTCGACGAGATGCCACGATGCCTCATCACTGTTGAAAANAGCCACAAAGCCAGCCGGAATTTCTGG
+
%#"#)(+%%(+($""($'!$)"$%")+#!($*&*"))$*)+)%"''!*'+)*+&%&++"%*)"'&)&!#
@r9131
ANCCGCGATATCGCAGTCGGCGTCACCAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAATGGCCAGGCTGAAAAGGGCCA
+
'%0D$+4'H7'8!.A#*0DE'B=*8.)9/<CBE91'0,:;&"E*>,7FB025@@=&#:.(E@FD<GC4;-7>63G*58G;,)8,750A4*3!>
@r9132
NCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCNCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATC
+
$G$$F@-%$;%F.?2-0659=.1+23;E1D55?H,<"2!F9A%#$&:A#A=2%9F@B$9H;?/%3)#8?8F>B'%'+(,4/,7,":6B=E!E"",&EDD:;=*E;A0"<(E92#8.0;+,(3486)/*#9D!)&8B+E?4E+<2*;7;#G=#;?5C$:)'>BAA+B6;
@r9133
ACGATNATAANTTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAANGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTANTAGATGTCGTTGG
+
52GF6$F7<44;#?:'<-:'.5A#7,07(!-<"%C)D+&/*;+9H/3F<7A5A/G7*<0#84/(B"A9E2!7F(%F,=A433-&&C%28F#D"?*':$&HB8+"--3;A@=G?G'
@r9134
CTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGNTCAGTCAGCCCCCGGCTT
+
AF20CF;<9'23>48A(F@.6DHF9:)-!%&+!?:2H1#C?-1E+5.45G%+*<&A8(6C=8@5*$<6-46:>>C;<B@:F#?AB%B>F3'<,)%D)-,,$$$-,E
@r9135
TTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAGGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCNTTTATTATTTATC
+
7G<>F;@E@"95D3,="-/;,E;3%F,A-(D6A:.,$"$%/G4'G0&,<>,&:@CC9C*3;=(*B/>3-4;(;)&()DG;#;B!!$F53?*=*<G,-4D;'4<98!B@-EH=:-AABF'=G
@r9136
TAATTCATTACTATTTACTGAGAGCATTCAGACCACTNCACAAATCTTTCCACGCTAAATCATAACGGCCGGTTTCTTCGGTGTCAGCACCGGGGCGTTGGCATAATGCA
+
)=1C=@16,7#B"5@G=ACE988036).0/F!H%.C1E:&?0#:7=;)6?+5.D;9C=0?$7B0#&>D@*(?3.9=F@<+0D8+9)$55);BC0)2D-7&@C>?)./561
@r9137
CTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATG
+
/A==3'4;=/G.E-="!D-3=1=D1;<59%'*5,?(.>9H+><7C)'F3&.!H4;#AB'20
@r9138
NGGCCGGAGNTATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCAT
+
#%++#"&#'($*"'##*)$##'')"%!""()'+)#++)+()()("+'!)""!((!+$)+))(+$!%&(%"+'*))%$$#*(*$&$#"%(+"($&*+$"+$$!
@r9139
ATGTCTCACCCCCAATAAGGGGATTTGCTCTATTTAATTANGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTATAAGGCCGCAGC
+
1+>E5%BF"68">"B*4D-%>908BD;6<9+53&77/>)03'>9D/"$?@'@%$:2$5<"4C3:-H/.0.'G3,;/38CA73$6?7>"2!#F6F1',@3A.H4B1;3-'$9@!5@#@/1)44A,%-1C%*07GD%HC#8<'9>!8?/7C>/1#.G4()G968!.B&H'>??D(-$,!#.3428/2%F9715'!.'
@r9140
GAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCCATTTTATTCACCACTGAAAGCACAGCGGCTGCCTGAGGAGATANATAATAAACGAAGGGCTGTATGCACAAAGCATCTTCTGTNGAGTTAAG
+
+AF)G9CHC88(.&02".5F&+83AHA1";/E/@->0A+,A&E80FA@A*%=G"$GB$(A+-DG(1GA%05*=2--(<&GH8)G'28'8:#C2/4'?>>,,F)#BB%(8/+A1.=:8<#:'8AG3C+6C7D;H*+E'7<>#0$;EF..4-%#?%C2A3*043?/6,5EB$F8
@r9141
CGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGNCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGANGTGCTTACCACCTGGCCC
+
63&870'9?72(:44#5H"G,*+:"!-.290)H@@F$>$":8H?:4=3,$3:+(F.:.C+0D%+)-'44G?%>(HE,F3>E4@*)AD8);(6&,!AE9$?<%#(.57:1+8B
@r9142
ACCACCTTAACCGCCTTTGGCGATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGNGTGACCGCATTCAAAAAGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATTGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCT
+
E1@6"?->.:3?7C?1.GE73;C.,2C;/=*>+#?>)F@%C:4')%CG2EA!755>2..9/$.0D').%?/#'9?2*&1=D/73)#5$(2,A($!?A)(C@A'??:D(F0'"'2!,4@/20E/-';&"FF3<!?GA?:@;&381&69<-,5#1"G1<84:59C>B>6->:B1=:662)<8"/&"FAGB@9C136)=E/B*@F,0#*4:2(>"%&.6*"0G/#H."G2A"H75<"3F6#@A(6H9!1GHB/C;62A84+1C*0H;?$&'(?7A-D"+
@r9143
CAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGT
+
/2+"/?;+3!379EE)D$&C&@8!#)F7FG3A(>;<9#-/
@r9144
TTTATTATTCAANAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAAC
+
E$"%D$>6):FA3)(DFC35>&*.0,-4>,5+(A27D@(7"F9)(2=)0<(1-A
@r9145
AGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCNGGGGAAAGCGGTGAGGCT
+
<(FD4E1FG7!<>4=5%47.C2%8G/"%5;5.C!.E((HD,,GHD>C;.$D*.?4E1$@'!'-<==1FB*"F*2<2B
@r9146
ACTCNATAAACACGGCTCTGTATTAAATGCTGTATTAATCGTGCTGGCG
+
;*ABAA(GC<-=F+4%A71;@80@>)4;DA(,""88G8&)%&2)6<(50
@r9147
TTTTTCGTCATGNTTTGAGTCTGCTGTTGATATTTCCAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATNGGAGTAGATGCTTGCTTTT
+
H%!2BDAA5242F&!;#9%:.2?AD3E&AEA3H*C$C@0,%-.951;*6EG:7(E7>#28,)DF?$/F1924G#6B"<"3'F7&#*?1*;7'9(.A6B@CHF:-3,14;;H=!>87/>1"9:25#(9<0676*)*'9,*,6E%:<=74,#+)EHFD=C7"65",G6C/#!2>3EGFDB50=843
@r9148
TAATCTTTTAATTTAGGTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAA
+
HD8HD3&<..-)AG7D?@1C>3?G('B849,,AA<HH@0F<F/9:*(26$'9F-(C5G"3)&F!/G.)<@>*3
@r9149
TTTCAGTGGTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTT
+
;+?"2(>(2/8*3<9<!3#,EF06<F%,@$.#/%F?/D;.*$$0<@
@r9150
CTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGNTTATCAAGAAAGGCGTAAATTTCTTTCGTCCACGGATTNANGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCANCGCTGGCATCACCTTTAAAT
+
:&.$4#?9='C9A08G<F2AA"-,0H:2&',!C+)5/2E*F=>+<1!)409C?56#;4%C$+-+F*+9EF5@:6588&H6/0>E.G5!##A<5DCG:$+/3.@0.(E%>%0E76?#>)4H*6%?=(7E+)4%#%+!205#)A;H?5@?B>*1::F'<=G5:.?@@$(5.
@r9151
CACGTGTGNTCGCANTGNNNCGCAGANCTGATGAGCGATCCGAATAGCTCGATGCACGN
+
(($##&)%"&"*#)($(!"#*#)+("!)!%#)'#%!(#"+!)&*%+!&&+&!!#$&+)"
@r9152
GCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATNTG
+
/E;E8333B>+>:5&4(=9@:?9B?DC1"4B(@+(.<42G"9FG,0H!G#=53=):H21?C@=D
@r9153
GTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCNCCGTGAACGGCGTTGCTGCAGGCAAGGTCAACANTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAA
+
4A0$#E8!>;.'.:H4<()?:.H/;C&/=D?!1D2+F.7"=A==$?+!F=E%@FDG',D@-EE;!&*4=4?:H;!++D&!(%A3C.<.@6*.<A('/,/@(FH1#6.*>1=-H?D%;6#;=)75%!F#(5CB0E
@r9154
TCGTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCAC
+
;:6(C"3D$#;%G-(/;)8"C*(-(6/,42A<!'H?54>-%=F&1(4">2%(9#*(;7+92-B-#>-6>*/5H1=:54$A6>-7!>F54+"'950)9,/29+F?9G(8$@:%D>!>*
@r9155
GCTTGTGGAGTTCAGCCGATCTGACNTATGTCATTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTA
+
:'6!.?ED/#E63;62'%(#A!"C2*C%6-E:3(9C#%3)%0,";52!5.27!#GE9,H?C*)@HDE(*#(;&/@?
@r9156
AGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATNATTTTCAGCTTTAGCAT
+
BE*7E=1)B8/&<D,/A*H>(%(.+5)?$@$6,140FD,4G"#53,2'B9B8EBD2EB!F!9'./E'2,142A0<
@r9157
CCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGNGAGTGAAAATNCCCCTAATTCGA
+
+/5.C7<8<+);,&<+A(2C*C5(99EB$"1HE7D2,0(:35!4%BB;7)%&:G8B80%143;"5=&?3<:'#G'$50E<'(:;<<0#CA1!34+7'@C2C:?:?+0161)(=,+E9',.+,5G74:("0--9''&$3&)E(.C1FC59;FB3.('H0;5.0/C%17-73'#"%33
@r9158
ANANNNANCCCGGNGATTAAGCNCTCACNGNNNTGGNNTANCNCAGCNNNNNNNTNGNCNGNNTANNG
+
#"!$"!!$#$$!"$"$$$##$!"#"##$$""#"#$$!"#$$$##!""!$"#"!$!"$#!#!#"#$$"$
@r9159
GNGGCGATAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAGTCGTCAGGAAGACAGTGCTCATGNTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGC
+
)$64@)9E79F'<,F(43H@?H"+&9(+829)@&'!CF;89*&6694E2#/E8%.('#0E!E2FF2'=%'21H9E.E=>2=;BF;4C>@86G.'<G<G0%57*5;<)E4>D!-<%&,$1=C.?%)9*%2D/*8+:C#+3;AC,#&#A%0)86,F.#%-(?!,H)#0%E*31=-(%(G4+;68;1&('F?#1@
@r9160
NACGTCNGCTCAGTGGGATGCCGGACATTACCGGACNACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATNTGCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGA
+
%,;+$5'*:$,*GA59>%+>6>%85,EB5!!%=/@8=F:,/6&F6'>B6;8H11>A%D&56:D!5#6.!>?DA68*;DH"9;0A*A87?<&@55!*@G6D0,A!5,G'9#<%D9G@C6
@r9161
GCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCGCCTCTGTATTTANGCCGGGATATGTCAAGCCGAAGCAT
+
+(G*)B.0<?4H0'!G/(=;6<!H;5A;$##!@/459!*H1>#1E4@(&H$:7@>&G3HA@3B(*E@5-),41=.G'!==G/><6?&A-C3!$H87
@r9162
NGCNCAGTGCTTNTCCNTGGTGGCTGGTCTGCCCGAAGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGTCGGACTGTTACACACTGTTCCGGGATGCTTATCATCTNGCGGGGATTGAGATGNCGGACTTTCATCGTGAGGATGACTGGTGG
+
&(("#%*"$)'$'!#)"(+!)!))++%!%#"(*#'+)"%$#"'&*!()')'+(('&)*!+($%$'&!##"'+$&$')(#&((&&+*)'"(+)"$")")"!#'#"!'('&("(&$&!+&$(')$&(+''%%'!)(*%%''#+*+!#&*!+&!)%)(**%%!"(($"*$%(+!**("(()%*(+&*'
@r9163
AGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTT
+
.:%315)1F:/%D<C*39'B+,:<13H,'A;E=9:$''4("0>C#"1)8'-38:1;,"35-;D6(5.$8:
@r9164
AATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATNCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCA
+
/@$/1;"D>E.$##+EH:18//A'4*$2@;7%>.,7D(A)1+A)5:-00;8?"<07@F'$!7C,BE<%$#!<;E(#.D"8A:80G%H!F/=/+9+??/!<!.@!H:85-&><A"=E#7#!?*'#4<2E8"C?'H8?
@r9165
TAATTAAAACGATGCACACAGGGCTTAGCGCGTACNCGTATTGCATTATGC
+
+@B-HB3-24;2+,0).H!,CB@38<%?D-D?D2C+9%>022967HCG=#!
@r9166
CTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCAT
+
&+$%$$"$+)"&')&+*$))")$)$(*%$+*&'!&*(+)"#!+()!%)"'%%!%"%#(#$(+%*%$+&()*%#*!"'+"$%"#+*(*+)%%+($(%!
@r9167
TGAAAAATNTCCATTTTGTGGTGATATAGAACAGACAAAAAATATAGATCATTTT
+
F2)'>=:60/>HDF4*)2F981:<(;)),FBFD4?2)@GG+?4/>@-)DB,#9--
@r9168
TNNNNNNNTTGNACAGGNNCCTNAGATANNNNNNNNNNNANNNNACTCNGNNTANTNAAGAGAGNNCANNNAGNNNTNNNNGNATNNNNGNGNATCCTTNANCGACNAGTACTTCTTTGTAGAACNCTACNNNATNANANCNNCCNANATGNGNTACCATTTCANNCCCNANNNTTGCNCG
+
""$!"$!"!$$"$$#!#"###$"$##"$$!!!"!!!"$#"!"!"$!#"#$$""$$#"!!!"#$"!""!$!!#$!"#"#!!#"#$#$!"!"!$#$"!#"$"!#"$##!$"#"#$$###$!"!#$"$!#$$#"$!$###"$$$$##$"$$"$$$""!"#"#$!!!$###!$!$!!$""$$#!!
@r9169
GCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGNTGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGTTATTAAACGGGCGCGGCGG
+
>E0'-9'27#8:=!FG':,DC45$!(/A/)#84EAA@/A<25<<8%.)BD,?7C-!A;>4#?=H0GDC,B+.;&9?H4'DA>/:A22AF:A@$&)&%$.20&G%;E#CFA(A7#FF,/9'">:F*8<%C,A"E7)+455082F45
@r9170
AGAAGGCGGCGTCCACAGAAAGGNTTTCCAGCCCCCTGCTCTTCC
+
*#+(#)$)$%"(**'+%(#(*'#+!$"+$+++"&)&&'""#"%)!
@r9171
GNCATNTGNTNGANCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCANATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCCGCTCTGAATCCGGNACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCNTCATCAAAAACTGCGGGGCGACCATCAAAAAACGTCGCC
+
('&#*'&*""!(*'+(%('$(#%%*!&&$(&&*#%*(+$#$%%$+&#()&*&)')"+"$%(#%('%$))&+%+$&%%!*"!$)"&)+$"%$)%$)'"%!#***'#$++#%$**+$&+#+"!&)$""")'$%&"('$!%*"#%*$+&($+()"'"$')"*((&+$&#)$$+!*$(!$#!%)"")&(*!!#"*!"($*&#$$"%"+(&*(!)($*&)$"!$"'&"#%*#"&"*("%(*'"$+%*'#%($%$&)%$$&'%(!&$)'("!!*!&'"+&('"!'!"+$))"(%*"*'%!)%&*"'!!*"#"))$*'"###'"$"
@r9172
TCGNNCNGTGATAATAAGTGGTGGTATCCACAATNTGTCACTTCAAGTA
+
%$&&!)"(*+)(*+)%%%%''+&%"%)(+$(*'*$$##!%'$+!"(*%#
@r9173
NTANAGGTNNTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTACATCCNG
+
$"$!%&(%(%%%+((!!&%"&*+*&%'#+)#+$%)(##$+!"&$*$!%%$&&*"**%(*'&%+!"'"%)#'%!
@r9174
AAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGNCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGTCGCTGAATGATGTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAAAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCG
+
!G.GD.(@:7;;26>B+C;C?6;@8*06@9@58*@525)@;/(!((*%5)1::0+DG'!GD1G!32;D=:8>"=4A7F+!.<1!7-.?(==G*=')<6#;9E8!1D*(1<E#;!)><H+!<@E2E&B8;()(>,<D6-=<2!5H01+/D3>E=+.>@1%CDH48E"/*3<#=+=BH3H4145++#G<%'05$E:GG;C:E-BC9*?"4.C8F,47&G>;:+&<-(4%84@'F@((C**4+>H:240@D4(G<.AGG":$:%.H,3C'?8;%B?C<1#-=A15;G<;'D=6G<5<"=1/#)C2F0&!0%E,@#4$>*'E1C4'>ABG)H#)4%?8H"H)AF,2%4#%C1:9<C;<,5#<E&%B:=D=$.>4.(/2,5-%).%;?HDBF)A'=/95.86%610H3,@4$F9.A)91GE+3'5>)H>0;$>6'6
@r9175
TGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATGCGCATAAGCGAATGTTGCGAGNACTNGCAGTACCTTTGCCTTAGTATTTCCTTC
+
#E$D=)<3@?*E8(*++.$(>3::0H,A;#5$>"D@31@F!+775%%9F56G''2+/''BB2<@?F-//!1/-&?F/C&;HD*<*C&;<5"&!:
@r9176
CATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGT
+
/895%&82C!.+#GE#"".-!C6C7#)G:*4@"1AH?9E46,(-G*>&+D)
@r9177
AGAATCCCAAAGGGATATTTTCGNTCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTC
+
2(6+=:G9B"F*@(=.;D;"D5"'+-(%*@:>C:01DCC!$4:!G?"H@<>))"5/#4:7'FC7D0$
@r9178
NGCCNTGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTC
+
(&$("92%3-*1H.)24:20;B:58-"?>-H4-C'H041)*;-61!*BB
@r9179
GAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTC
+
++&)+((%)#*##)$*"*$(!'&$!&%%$&(!%**)!"&"++$&+&!"**+!)&'&)*()(##+")$*$!*''"%#$+)"&"%(!*(+'"$'''(%''%
@r9180
NCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTGTGGCTGCCGCTGTAAATCAGCGT
+
'"+"$#))'"##&"$'%+)%)"#%#+$*#%'+"'&!)$!!"%%")'"$(*##&+%"($"(&!&'!&&"%+)#()("&("#(+$!)+*'#"'*%+("&(+)!&&+$*%%")#+%'"+'$#"$)#&'$$
@r9181
AGTGCATATCCAGCAGGACATCATGAAAATAATGNGTACTGTAAAAGCGGTGCCAGNCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGNGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGNCTGCGGGCCCGGCGTCCTCTGTCTGTTCANGGGCATTATTCACCACAAACTCATACATACCAGAC
+
0-1?)=2B44:222;CD"*DA"#A1#C3+9#:GD+.F2-"!;5=H?$6C;/A%*5H4EG9CG2+9G.+</;:3-(;.,6%;)+@;FC(H(F6G9$F=A9.0H#-,*:&)$-FHF(%?.!D=&$28:AA4G,9=?E8;>!36<">==8?(%&$2%#>2E*;1.<594,*:5:E3.#0#<<;$3-,4@F+11AA"'<*(%.D5,D9("!"B=,'7B2>:7=<4%?0F+!67.EHH'@A5:.;A<",3<
@r9182
GNCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGAAGCAAATCCCCTG
+
"!=5!<;28%-+5!35(>AE=7!%50$CA*5;#:<&"(9,4+8&B:+4"!=
@r9183
GCTGACGGNAGTCNGGTNGGAATTNAGCCCGGNATGCGCTCGCNGAGAATANCCATCACCAAAGCGCACCTTTCTT
+
*%&$"#'$%'!&$$''$#(#'$(%$("#%)'#$(+%#(""+%!"&"%!')!!"()'+&+++#"(()#($(++*(*#
@r9184
TTTCAGACATTAGCNTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCNGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATG
+
+!*B-,6=4A!G;*8";"/><2*G.%=)A'&H60C.++E)#!#F#!'F;?/52#:028F?>>:@@+-(7%.=85@=?$7>5=>E7.7<0!/;%"H*5#"%D7-:(55;$=&+!A.ED5B;5*%731D365@2%!1;*'/F&+5*-+G,F
@r9185
GATGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGNCGGAGGATGACGTAAN
+
?=&;87H5H.3=65)D6D:7$;"C16#%#7<;B8%04+2$+$0"A/%F"<E8"C2H,=!D'/F1A(;5$<C80C@/C%&@DF
@r9186
AGCGTCTCATCTTTATGCGCCAGCANGGATTTCTCCTGTGCAGACAGCTGGCGACGT
+
@F4<GE=+G'<H!E-)A:D?&,48#?>:5D,=C?5(,!+-34@"*D30(-43!+;$?
@r9187
CCGTNCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGG
+
<.1<3.9,5$F"H2D6$.@8-;A>/@!=C24:+;/+AGG.19!
@r9188
GTGCNAATNTGTTTTACAGCGTGATGGAGCAGATGAAGATGATCGACACGCTGCAGAACACGCGGCTGCAGNGCNCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGC
+
"%$&$)+$"*%!"&"&&'&$!%''("*+#$"&#"&'''$#*#%**"*&*)*""!(*%%$#!#""+#()!(&&'&)'$"#!"'#'!**(#(%'%')#"!)&(+)&##+*!"))#')%*%'("$$$)*#!$)%(!$#+'%&
@r9189
CTGCAGTGACGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGG
+
00!)04=./D684"29'/@G0,)2A'#<>B6*>8%:'"9HEDG<A4*B7.C1@$$EC2%$$F<D:3)*;-)5CEBHE+G%D;G8=%89)*41%*A74:9:*8=*2#8AE"A::C+#=2-'<("DA1,*<'1<(-77BF-0!%>6<$@1-9H0(B;'?D*"A,4,G5C&2+,=7D.")'56-H5.=+6E&54**&:&,4=<-4-@
@r9190
GAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCANAAATCACCAACTCGTTGGCCGGTAACTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCNGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACA
+
#E7C2%?'AB!5BC:%1(+H-6=&'0E4@E!'=!D$<,90CG;,=.>7&B"#;.3+D#>=B:"H*=?!<?3D;4B8#FE!%@&C#'&F5%0.5)$3'.2,"()-0")""0B2,%AG#1-B@7<7FF.'6,9B?$&!';"H%+H.C'4,E>D'*<@%49H%,&??E1.A!D1'(7&,9@/7+A-#=:7/82..7+-(3."G39B;?=E/&G3=5');7.04A?"9+051(:>;":/(;/)F"<0%-7E$,(<=>;9E7+',#8$*1$>8:7;&@2)?A&'C0HF7-%'B>=H9-%96%4/
@r9191
ATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATNCCTTCA
+
2'$24#;*;AB-3-013H8+9((1BH7&2$3"/!&/89.,4/.C4G..;
@r9192
GAGCCACACTCTGGCTGATGGACGCAATCTGAGCNTCACCGCTTTCCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAGACGTCAGCCCTG
+
(&&*+"*))+$)"%))#'&%+)"&+!)&&"#%'#%%"%$"*!)'&("&(+%*')((*'&$#&!"#)"%$!&%$()&$!$(('(+$%$*&)#!)"(%!##+#+
@r9193
NCNTTTNTGTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGANGATGCTCTTCGNTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGG
+
%)$'&!)&)(+%&*&)(!"('*+$'!""+++"(!&"'$%#$'**"%'!)*!#)#!)('!%&($)#&!%)('&*'(!$$!%$)+!+"++#&"$$)+*+)&#&&'*'++*"%!++$()'%*#"*
@r9194
GTAGGCGGATCCCCTTCGAAGGAAAGNCCTGATGCTNTTCGTGCGCGCG
+
;-8;3)3HE?1E'=&("2!2/A*(@,#<@G,1,7@&;A#"'C?G6$.@0
@r9195
CGGGATCGATGTGNGAGCTGTCGAACAGGGGGATGATGCGT
+
4+20*3$/19ED$662;>'G.4"4B)*"EB.$';7&39+EE
@r9196
GCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGG
+
7@FB?1@?91H9&@.3%<+F,@/F,=5+;12H93.,3+)=E75;#%<61<'C#71HB-&+
@r9197
GGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTC
+
G!@7-B>%58;45%0;1**&-1%2.8,C$*):.D9?6.2BH@7
@r9198
GGCANTCATACTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGA
+
+&38"C*12B+B;.>E337G5A=.>/HD%D)8*7>25,F-+.%8730*
@r9199
TGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTT
+
'@5E4602'-C3F,=/.(>D%,@&G%)4A()"0:%>"5<GE,F:H;$#
@r9200
CATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCG
+
6-"$E9./9+%+,A/B3E@:?8E$')*,58F+=$!6F9F!AF=7?>G/5=<'+3.-/(F&A(.A"#B4:6,0:>$$,H
@r9201
NGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTNAAATGTAGTCG
+
'D<.&D5AG<0.86$-/2'A%8:;30><:F8$&-#D2$(D6)G/G0D<2%0
@r9202
ATGTCGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTANTGATTTCNACCATCTTCTACTCCGGCTTTTTTAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCCTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCNGGCG
+
+7:D%):4GDG2%4-%<./1##38//+;"*FA'.>D@)+2&6-81!'?<@)E()B2(D/?=.-",$@.1/6A5@B5(9/5)F.=5@9'<:(2=E4;<D%),F85%&@E24F!-,H,%A?:5+386-$0$%H;8GH3!#@<"D%>(9>;G#EH%HA7E-+)F'%785(A'1(;*E"=";=1)3C2)<E,$3<!7*!#6*6?.F>.:49*1-@F1FH/?'3!@!G..H@7??:=4;-7;/)>:927H-E3+=
@r9203
CGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTG
+
2A@'AD@HB@#H:>&)A08H3%1F$50#"H;+74H,/FH3C&7G
@r9204
GTNCNGNNNATNTNNNTGCGNCTNCTCNNACACNCGAGGNATNNGNTGGNGNCNTTCNGNCGNGTANNCNNCANNNCTANNNGACTTGCCGNTGCGCTGANCATGNNANNGGTNNCGNCNGCTTCNNNNGCGNTNANNANTNNTTNNNNNAANNCANNNNGNTNNCATCATTNNTNCACNCNTNNNGGTCTNNANANNGCGNANGNCGNANCTGGNTGNCAGNNGGGNNNGNNNNNTGNTNGNTTNCNNCTCTNGNGCNNTTCNTNNCNNGGNCNAGGNNTGCNGNTNNACAAGNNNNNCNAGTCANNNNGCGCNCNGNTNANTG
+
"##$#"!#!"$"$!###!#$!#$#$$#$$$##""$#!"#!#""#$"$$"$$####$#"$!!###$"!"#$"$#""#"##$$#$!$#"#$!"$!#$#"#"$"#"####$""$$$!!!$#!$!$""#!!"!#"$!$"""!$#!!$$"!"!#!""!!"!#!#"$$"!"####"!"#"$#$$!"$!"!$"#"$"$$!"!$"$#$##$#""#!"#"$$"!"#!"""$"#$#!#"$$#$$#""$!$"#"$!!$#!!$$"!"!$#!!!"""!!$##"#"!!"$#$!!#$##$"##!$#$!!$#$#""!#$###"!!#$#$#!"!$!$#$!!#
@r9205
TTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTT
+
+<,.5@G-&55,D3??4<*1@3((E)@?=3*5C'8;)"$,-C,6?D:8H5F*8+$B>?CC)E,#>/#DE
@r9206
TCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGAG
+
D2.&2>8E(F0#1;7@E/#43;)::#/E>2(7>G7*8@(5?D5(3G+!+C(/"2B.>17.&
@r9207
CGGNACAGAGCGTGGCGTTAAGTGGTTAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGAGGGGGAGACAGGGCTGCATGATAAAT
+
(((+%#$#'*)%+%*'%+((!$$')+&'$'$%)"'**)$+&)(")*!!$'"*(&**)**$!!%"&!($*!(!'!)%*$%#$)$!"'("(!
@r9208
GCTGAACACCTGNCNATCGTAGNCAATTTCTCATGCTGAAAACGTNGTGTACCGGCTGTC
+
()'$$(!(#&(%(*!"$&%#$"$$+&$)(#%+"&#*$"&#'$'("&)'!"$+)#%#(+)#
@r9209
NTTGCANCGTTCCGGCGATGAATCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACANGGGCACGCTGGAGACCTGGGCAGA
+
$($$&)%+#*$+"('&%)")()(+""*$'**!"$$+)++**!($$!)"$)*!%#$'"++!'*%"))+!)+"%!%!*&&%!*$'&+*!#(&*'!&+)%&"*&)++"+)""'"$&)*('$$%(#'
@r9210
CCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGG
+
9D82+F<%;8/A86B6.B&-',9#6=BH74%CB3+)=#D"@$($H)A*&9/>2/&6-D-)2(:1HA,"0A*F12(6(1-72C8"(E5E2)G;7H)E!'#7:>CE0#=G(,="?!(!5/A:$<6?7<*@!994H4A;0;&")&F*3$,+))E7*$<
@r9211
ATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATNCAGGTTGTGAANATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGT
+
6>>':2A;><"0<&=;?4A.*(*.>GC'944(D8A,>+%-A*FG,(-G-=40807E*=00:@*<3C542A06(BB;A)G80$B$EC9+'G@=;D1F./@096&F7>*A"(*(+;=1D:)</@F<'*"=?0486?-::%,D?1@=9&,-H8/:&
@r9212
CATCCCCCTTTCATCGGCGACGGTTAACGGCAGGCGGTANGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTTTCCACGCCGCAGCTGCCGCACCTCATC
+
8,E(=3<,E-C"""4=-3'7'/"9CH6!#9/HE57+/A%/3D-=<<5>&5E12C$0'C4,/=%50)-37@<E9G!:A7D2@9<BDE)5,#5:1647AH!G!'6/F#@#)>!DD6;8E1@./%C;:*-E%0/62CH%H4H"GA'5#17'((HF**C3"
@r9213
CTTTGCTCTNTCANCANNCNNCCTNATTCCTANTTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAANGGCGTACCTTCGCGGCAGAT
+
))')*"%'$%&"&!!))!(*#&%'!*%$+)'&)$**(%*&+++&#+(%(!"#&!*!(%!("'!#%"&'**$+#*+(!')#(+##&$$'&*('("'*#&#"!(!''"$$('""#!!'#+'$'+"(**+)"'+%)"()()$+"!#+"+'"*"!%%$)*)(!#**&)&)"(%#$)''
@r9214
NNGCAGTCGTCGTCACCAGGTTGCCCGTGAGNCAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAG
+
!"')%"+"'""%"!$+'$(%"(%(!))+!&#"()$(#!'$+##)#&"%($''$"&&'&'*!+##(#"'%
@r9215
GNTCAGTTTGGGTTTTNCTGTTGCTGGGCGGCGATGACGCC
+
$")CAH;:F@6*8F,.H93'B!&"36%-$879=;;#$!=6D
@r9216
CAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGC
+
%#(++&)*())*#%"(+$&*%**"$*!"'!&*()*)'*$!(#$(%#''(&"+"(+$)!))
@r9217
AACTGGCNTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGNTAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATNTGCTTTATGGNCAAGGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCANG
+
>'6:G0@39CF09&:%0@C'-<5+6'+1D(F,3,-,*)E6!1+95)8FC7+"*5$2->C/=<9'HD@<:3/>92@$AGH58F?6(7;24:,';@#9+<7+"":%2)9/'H;..1E@(1H@F*@C$(/C0-/%189>A$4&24??76!54"+)9:2>B156A=@":+B">!+?E966,(0;1$%@5%0H5?>)8>,=6G6!
@r9218
CATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGAT
+
F>AF3HDDC0#A!+*%*4&>6);:E#?>65:G17,+$;3H%FB:1B&4BHC
@r9219
AGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGAC
+
+%*'*$+$*(%'$#%)&"%&*)&#&)*"$!('))+##)$*!*))*%#)'%$+"'$++&!#&+
@r9220
GTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCT
+
683C=75</F0;35%(<",2.@?-4#A3>C')&4+A>7B?C
@r9221
AATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAG
+
=80:8:8(C""7:=*;(6,@/-?=1<*H=(!3=+/,+949E*2(B04F#+343H64A+53F<0$0*#$(9=>B6!$G--8.&.*:?8
@r9222
TGATTTCCAGTTGCTACCGATTTTNCANATTTTTTGCATGAGAGAATTTGTACCGCCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGA
+
<!$H>2-$@%?#;08DG%46%.A*,?&@D7'E5:>3B,8H37#0,&B!8@C-.7?8HA&*#=$"<<7)!)<:+%1/*F*1-77H;?1E+FF>(G@$)D2743#,=&B/H5";E+D514H-54!&+=-$EE5)C71$G&-?*<0A$#/7HH0**0$'A)=3A
@r9223
CATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACTATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAA
+
,;;4#(B'>0"+=?B8C.-BC+%A2;))7360F*;89F(G,#B-<30+5G*?:?09;'9%?%<-GA-G'CH&@A9>##!*8)4B6EB-B,0B+%D<FC1H>E>==;"%"7F
@r9224
TTCGGCAGAGNTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAA
+
:/CF-+ED6&3FBE3@:!/+"%'=F?E:,:(/&C*/CE).=.$<9,7*E,(461<DEE:)D36/+4AA,-495
@r9225
CTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGT
+
+!*"%"$$#"$*++'+(++'"+&%&#+$)'#(%%(+'#'&$%'"++**"')()$+*+%&$+)(
@r9226
TTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGCGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAANTATNCCTTTGGGATTCTTGACTCG
+
8%B=GFDD!CHF"+)6?/4"D;.,A(/'1'93!/:+BHC$'6A;+'?%%+4+3=0F:*$D-<2@1C(BB8*F#?6!97'7B"$>&472%%;B!$7B670,85$A1'E4)&9#D0066!D4&G4%.1+"*A%;0/"@93>5@',*0D1/$+?2397*
@r9227
CTGCTTAGGTGACGTCTCTCGTCAGGTTGNATGGCATGGCCGCTGGCT
+
9BD1)(F5+?AG2<@$8ABD%#0+#1/C;/F%3F-26D,9(?#GE*>%
@r9228
NTCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGT
+
#9&FB8*96=0'G91E)F?A$:H(A2!DB#7*-60#')&'*@B+66+94;A=.H'C)C
@r9229
AAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATA
+
/#F04?F7'7<'E5!!465#BE-H%C>%(:!.+,-3:E$7E',"2+/"&H?91H=&<&B%2)/>0#B1.6!06G"-D13'1DG-;1!44@)1:
@r9230
GGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGCTGCGCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGNATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCA
+
(:;E%D5C*1>1;,97-&/;9*5*$0DFG)97;24=%$+0E9)C:E3-/F(5*1)5BF**B-)8.#&!$9G14:DF%)3H76F$;4EHD>3@+C07G*,/G$E4#'-#-*:3$3,5"C2FF4DDB#%;65C)38+(!">.;(!479EH99.+%0#"B)*H0HD%*:>H#+F+'83F#<E86?7-*G7GF$8F!F787H/7%.$@6AA8=4G:9"0;.?6#DG%F?
@r9231
AGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCANCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCN
+
;D*G98A;+1"',%#.@<B,6=8#?">(G/D!3D'$7()(.(&-:&F9D)CB,4-.4./:(;'&H&GGA,>1#;.
@r9232
TGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGC
+
=43&,7D$5$99;@'=(31";#07=1;D#33/7"#E018@0<@
@r9233
CGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTAC
+
2/28>G?.B(-/9""%6.1")8G*@=;C;*0B>,B?-.B4*?*2B8518B>E!D>@7!02@83%D:1"#7@/C=?,3()35-8.?C
@r9234
AGAACGNGGGATGTTCATTCTTCATCACTTTTAATTAATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCAGATTTGTATTGTCAGAAGTTGTTNTTACGTTAAGTTGATGCAGATCAATTAATACG
+
2=058:E;5:G$42<2=7:8FE@;D<./07$*9-?;6960D0DHAF2651.6-'?>2*11B(600<-DC7##*4C-8G.1$>9$*(%?,C$2#A>=H9(&C'C)7&EC=G!=7@!"EG=C;B+.?B#.!6*09B35=,;@?4))5-;'>2E@4$96?B$<;'0-EF#;8+0097B@=8$#6F&9;G4HCB99-$4-45..5:7@C:)79B@G""</'48;-F6=5,-!35-%5&H"),<D%A/=)92$#?0&A0&*3;-'E;?.<@3;499C5=3G400FE(-:&%)(=;9
@r9235
CCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAAT
+
,;>6GFH5@B<3605<H&E@!(A/4/F!-8DH@9D2HC<*%,8?;BFGD27-+E5$;2(>2DCA$/;;D"A73(40868+1D.>;,!=3;1F5!=4+./1BC
@r9236
ATTGGCATTGTATGTATTGGTTTATTGGAGTAGNTGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCNGCTGCATGACGCCAAAAAATATATTTATCTG
+
(*0=>A*7?>'41>E+%)?>5H3B,/B,D&!?#.4-B,F/D**11!*?@-1A57.+*H!EC/#77&?,3089.9%,#C6&$&F1=0,*1$?30>-E9GG201,7',)F1@3?A"<:$<62:<:?BB"/@B<CC3#/
@r9237
GANTTGCGGNGCGACACGGGTGCAAACCTCAGCAAGCAGG
+
!'$'$!&&$''%")+'")#"%#'#&!%$&!)')!%&&$(&
@r9238
ATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGG
+
*<3"$6%6<:#$>+>?+*A1@H.C1!E:,6189*!-9?GF=&%9+/,
@r9239
ACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGC
+
0+#5@C>H;B2,F/!H$8A,G*7(7!CA7FH=/:6B9(<!*E2E&(+DC:4B@/=/5!3->D
@r9240
ATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAGTAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAG
+
/&&20-6:#/A!$77%)H421<,9,:<C5C>&()"D%9@#3?;4.%%E$9A;!A7F/HF'F;?AABA*="D*E1'39;+&H"C%47.D
@r9241
NCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCNTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAA
+
&AH,;!?759//C%(-(79%)?7@-D?9,FF<5%<4A076#'(92%,F00."H?';,:?%:03;;'8)5.284#2-5=B(AAE&=8#*2?11A/*)'<!B(384&H8B2616:<DB6G2
@r9242
GGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACNTTNTCAGCATGAGCAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGANAC
+
+.(3@#;EG<;H8-8&=!&(>=@798.$9;C)G!<?C"0"?AC&(#3"C8/;$-<*HE@,3B$-50A++CB&2EE*0;0B=&.2&"F?F=#.0<%?=-DH#+;H=179$G;@,(&G:98.%*1./3=%D/.-,?$0(,DD++993H/GH?93CD!%8+.&+>>*0'-1A.C-D,C-7*?1B1;7A#)33$@/1.+F61>7D4<;405*6*
@r9243
CGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGC
+
=0-C>H*-1."#!(1>$&+/+$2>*6E(B>190&0@*)$5<*1159==05><=)@0+,9;#@##A;7=/#
@r9244
GACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTT
+
7%>2DG@,897!D0:8*597!6@*6#'(50!0E")/<:/G(06*'H<'/D7&1=+E(99B)"8G)'!>>B*16<+6-A5#H)5#E"/B:F?!2%*%H-;4:F=>36A$15271;'/&,<229
@r9245
NCCACCGAGCCGGAACTTCATNAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGG
+
!G=;=H34A..?$>1'@'?$#.3/#38DA<'&":@&>F%!4+6>3%65C,8&7&:.+%>&D+9F<D-'4,D>4>(A/42C>H$C@G9A3?B@1GHEB#>'%,#>$E-!GC&8=!++&C$#H(+FG("<'
@r9246
TCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTNTGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAGGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTA
+
@.,$F!;+*.0.=5B7"BH/#928'3+4)45AD+3H";-;>@*+*9#-;B,1+(1+F8.1#'!:4>/C<8'H6HE(H3.(C)/0DFD-2G"0+/$<",3/"*&>#C,;5'%-HC6E(*<&54B,BB5;.-1$708H=DB-+<2G=CG/2<)7@5-*!)":670A3%3F3F4H<:7C!%B"(EEG;GC+7@3D:3CC>(C7
@r9247
GACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAATGTTACGTNTCAGGAGCGCCTGAACGCGCTGGCGCAG
+
48)&>G1C3DF4<9-(%#D=;(,88B*D<#-57$748C"<=,321@'$FG=*'D6%<9161><>'*;B3*@F!.D:.6.
@r9248
CAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACCATAATGTTATTGAAAAATGGAAAAATGA
+
2@5,20!))0GG=F,D?6/BD:6:-&;/2('D&3&<4&329>)/@&/9'!%+EBH<H30;$4?8<58B;3,'G*+6-%H8E=(/9*!)=&0
@r9249
CAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCC
+
AAHA%C=$DG055#@)5%E(#/#1;E(/<>9?4#G.3+4?<1(;'.).9@*1=?)0)B$7F>/@H'EE=40001B:,EHB0A?5=(64)+E;'?0+(:@G'
@r9250
TACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACG
+
=6?H/#<8.(38.9%C1/F)0+$'<C(GC72D0!63?"G'/2"F492/>9%37/"E*(ED'8%790/*?E.D8DB.*69
@r9251
TCATNGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACANCGNCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCG
+
$+DF05FA!&%&93@)2H0918,G-C-/@;)C8.B,H(*4.*:A03D:B2-3'?227""#E/@B%41.E5/86%<G=++*'9'$27@''$0D!!9'$4E;+==(457*=A-3&2#404E2$5-3H=&>C"$
@r9252
GAGTCAGTTCGCGGTACTGGAGGNGGCGGCGCAACGTCGCCAGCTGTCTGCA
+
-*"BF-D!1F414$CA"79=4?=H.6E.'3E1A-<9>8/729H%9!*!("E@
@r9253
NNCAGNNGACGCCAGAANATGAAGGNAANATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTNAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTAANCACACCAAGCTCAATCAACTCAC
+
"!%*)!&'('*$%*#(&$#$&(&$#%*(')+*'"+*!&)!$#!#+(&%**#)&$(())*"()%)"+"!*&'"#'**&*(!'"+(*$%+$&#$'!#!&&(&*&!&+#*&($#$&+"#+""&%($%+!$*#&*)"+!!!"$'')$'$!("!!*+%&%)'$#$'')*"'$$*"$)$$"$&+(&(*%)&*&!!*%#+"%!%(#'$'%
@r9254
NCCTCTATCGCGACGANAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGGAACGGCCTTNAACTGA
+
'(!'*%+$!%$'&(+))$#&*&)!!$+((%)&""*'&*&("*&&*"!&$)(*&)#"%+!!%!#+&'*!'"!!(!+*+$
@r9255
TAAATCGTGCACAGGCTNTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGNACGTTGCCGCGCTAACAGGCGCAACAGTAACCNGCATAAATCAGGCCGCGGCTANAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGNGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGC
+
+6A(:%>5DB7G#A:G!&1B>*0%.9FH%=3#A#,+BB20%<D4(-?.8:1B)>+"=G3%+:%9H===&B*F0%'B"><&;HD19(=D0>1@D-<E9B7!2CB>*>@=879>$6:4"&F!;BB9GFFHHD=-HH=?.05<(8"DG!F/487F=5D&*6!$+$8='E)+!)1GBHB2*7:8=0)'C/HD")##,62#;:442(4)B&'GG>D"CG!#<F=-".@$//0,;!=+<$B;;!E*4/8)%"8#)?;A(8;4(+<%'1%/+90%$1FF+28&$()7A%D20&2E5+<812+<4&-359>"@&7G*&/,.1;800
@r9256
TTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCNCCGCAGCGGTTGCGGCAGAAAACA
+
B/D2:$93*"E*6+9FGD0=G@2.;-H"$=2'2B,='9'(6:;*12A4B++4*>H66=<+B:@D?77#.B+C;.CFF8583$>2A-;*/DB+-;82/C<>5.;>3"!#A7
@r9257
CCGACATAACCGCCGGTGGGATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAAT
+
8!#A-&+@5"$>/6+0+E$?8362;);62?HGC%C.-,5G?"3$A7?-;3)<>26F7G')5"-7:AG52ED3A>2?)3BCB-$3*':;*B<7H2HG':-&9#?F/4;E@<+F&A'0-GH#12=93$4HD/+$DH!9FD/B
@r9258
CGTCCGTCGTTGTTGNTATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGG
+
"='929,=#=2#4'C>/C/2+<?(-.3F-@5@:20:4/&3>'G?1-#3/..0!A;'#:65'2B?>3GG$03B8E488)%&;:806&?B'+.(F3H=--?341>)E>F?6!7F8:$FH'#D("!8?-"2F+HE'AC,E565+4/(1C&E*@
@r9259
TGTCCCTAGGACTGCTNTGTGCCGGAGCGGACATTACAAACNTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGANTTTGTAAAAACAGCCCTCCTCG
+
775'#;CBAA)""+!"$8!.H.%""<+)&:#C4'!;A7'!;9!4D;*"/-6=*,(446,?,A<)6<H;=G.G1'#9#!+&46$%/C*C$H.%/7B>=H5<A3H9=CE0(:$960$.*)5>0A&;--=#F6#+
@r9260
GCTGTTGGGATGNCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACNCGTTGCCCGGTAACTGTGGCATTTGNGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGG
+
423A;AB.<=>+4=-51>2;257*#9/,*#"C2F!0(9'!/A*.."2B?>'B>1&6;)">>*A:AH<#@(&C.3.89=C&82=26?-:3)'FD(&4((2+0-6/*C%GC6BB4)<2">5>+;=@$"#=H0):%822/8-?8:%/$()#(5"F-$/H(2E21@$<7&A76"26FH0!;!59?*B7#FA@GG8>?E/;!A<#E6;4D5@E*3+
@r9261
GAAACCACTCAAGTTTGCCAACCNAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACA
+
2$&FG$?,+F#/H!?2??,:/H#$H,>G85+2D7&1BE@&)-1+?#,!*:.:"D/HHG:.)B./@)9
@r9262
AGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGG
+
'GE*952E#"G*E'%D%B1'=+;$A$:F;3''$2'(!171#E;9-36352((F2$4:=#6%238-=F?22,<
@r9263
GACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGCACAGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGG
+
);E0#*?@.(1<4H#F@6#"9:?.3!:389'@9?4E1%3!*EH+H&$=>)&5+@129(7$+"9@AFH<?)+143$4DH=H6D0-C64#=G)=>&;6E&C
@r9264
TCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCC
+
90.)2<@F8&?'CH4,+0%=)>@FGD*/90.@F,2!H,";12#'A4?"
@r9265
CGTGACGCTTCNGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCT
+
.,)=G:*E,"B110A#:8=D"5#.>)2&E!%'=>0A5A3#>F0<9GC:?"/,)8#
@r9266
CAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATNCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAA
+
-&F:5(E8%,*1G"/6943*!24'/*1#B):.$+@=FC/3."E?:)G,#+EFC07*H-@/1F=$E!%*F5?'$?E3(FBF"F;62@?6<36@$>*="+()19=4B@$-*%<!E0+-6<'/0&EE-<HF$;.&&=&+;90@3A(74$A#$"4&37(-<(%5@#&:)4@9F1?G!%
@r9267
NCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGA
+
"FF764=":&)%(<-:#2?CBF")>;*<C&/<@7,0/7,9+9,/"@,=5/E/BH1(..@3##F'"7C9;5>-H:!+)"&C@1965
@r9268
NNTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAANGCGACGTCCACAGAAAGGATTNCC
+
%&+($!$""#$&*(#()#"''%&)'#&%(&$'&*#"!)**+&*!"*%($!&)"!%%&+)"*!
@r9269
TCNGAGNACCAGAACTCAAACTGTACCGTCGGCTCATAAACGGCAAGATGCGG
+
%&"+*)((%!&!(#((&("&!##)''*#''*!))#'#(((!*#&+#)'!"&$#
@r9270
NCAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGNTGNTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCA
+
'9=CH>:*!@B>DADB@B1.8F8.2$:6?)G1"C!1=?6;>9$E"?#F<572'/;@=*A;?$2,46,@<F66G:$(="%>'4(-*;76@8EA7>/)&9<?;&2E97$.)5''%3C4&>01'2$@&/-$39G#7:$)955.3B>,%F"F=@34$1)1BBC>(+GH-B)F:CH+C+&G82"3DD(F(/*66<$H9=42&@*=*"0>3;3:A=<>0A)A8BC++)7D#;42"6'D>!:A>,2
@r9271
GTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACC
+
,$5<H=>>+53:8H5CD;3G>%A1'2F=@"%$H;FH<(C%-+$-,F7A'#2>&1#<GH;G5HA/A85D7>/BC65BE%9;C+5$9%D99H*(0$.5F0;=78(=86(
@r9272
AGATTTGCTTCNATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCGTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGT
+
'H4:AC=A8(<$A3+'FE00;816969%B)CDC;68<,FF+@1:FH3%*/E'!A&@:;/,(/2/!B55H)&2*.:0#(-F0:4F6(@5(B-+8)-"4'H=*C0-);D5B@8+-53)?3H2FEH(/4!3E2;(@-0@
@r9273
CTGGCCGGAGGTTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAAC
+
8;D%,%-%(<=H=8+C&H",#-D=:8&8>H4F3%HG6+D(>-?9/5#4>7:/("
@r9274
NNGNGTACCTANACCAACTGTATGCGCATGTGCACCGGCACTCAAGGCTGTACCG
+
*##&%"*#$(&&)+(%%(!")(%$*%"("'!)##&)%&&&'!'+&'&)%&'&((*
@r9275
GTGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCNGTNGTGGAA
+
(E5:G(.1G(E;9,D,>9-)-E4'9-"1<!32%6;+@<F"1"33%G.<<,:@,F*
@r9276
TNNTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCG
+
#$!:E29!'A*=>*42"!"C,@F,15+C?C9D$>9/<:<(6#.&84146-
@r9277
AGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTG
+
6':84@$H.HB8'(7$/$/9F,C#'#3=6;G;.;%/',?-BH9
@r9278
TTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTG
+
93;%:!)<137(/+@-0/=C!AH=C#8.=$%6B;#B5>BAA146/?8:-!"&D86%0.0$0(3.@A/5+C)E8==4@0$$/B(E48#'#G.!H0*,+)5@2>
@r9279
AAAATTTCTGGGTAGATCGGGTTCCGCCGGATGATGGCGGAAGNTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGC
+
$/G0#H!?8@A.6%3;A=&>ED?8?8/)27,"!#'C2+@F:C.#08(44;G@<B&B$AG-$%E!"1/4(HE%$3BG.3?=4<=@F0H#;3G;?6!
@r9280
GATAGGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGC
+
DEC!A$$A+"5##HE/4"6E;&.F<'BD4-$+#')6#$$30A---$%F$(3FHE.H-)7C$2A.?95G#E.*:B&<D=#"C;A%$.,><1%-,&5/<F;.=
@r9281
ANGNNNNCATNANCCNNANNGNNAANCNNNGNNNNNTCNNNAANNATTNCGTNCNNNAANTATNGTGTTTACCGCAGNNNACGAANCCNNGAAGNNNNANGNGANCGNCNTCNCTTNNNNCNCCC
+
"!#"!#!"#"!#"!#"$$!"$"#$$!!$""""$!"!""!#"#$#!#!"!$"""$$"#!"!"$$!$""#$"#!#$$##$"#"$!"$!#$"$$!$!$!"#$#$$#""$$!!!"#!"$!$!!!"#"!#
@r9282
TNTCGGTATTTGCTGCCAAATTCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCC
+
8@9F!2!5!)/,>:=C#"$:E.=!:285)75BG";5'F?7<GH%-!G=3-#'D%")*"2"
@r9283
NGGTTNGGGANGCCGGNTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAA
+
#*&$%"!'#*%$$$$)!('+!$$&&!&#(*+%%'%+'%"*!%++"%+!*'#)&
@r9284
GNTNAAAGAANGTCGCGNTTNAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTANATTGAAGAAAATGNCATTGAGTT
+
"&#&"(&%*$$#!&%)$!)&*+(&+&'))!%+)#()!)$#$&((+$%*#$!+*%*'$'('*'&$#&)##)'+%&)#$)&!"&!*!%$
@r9285
GAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACNTTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTATAC
+
;=A991B:,.&(CA4!GH0-<,%$>B992#7*.H!G18!+,)0CB%H7%H3)95*?>>=&,0EC)A?0)#8".0=E+!$1E=/@#/C/0'B69+C!!1(0D!+)/<+@#8'<7C$22C+#3%.%"8$E&.;DE5+A"H;:7@&<.-<90@H!67;>1G@E*@%8BD57B24!
@r9286
CGCNANTGAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGNTAACNATCTGCGGTGAT
+
("*#("#$)*+"*)$*)%&!'***&&+!%"+)+%*#("$*"&'$)'!!*"#("'!*+*+#+#!%'+)*&
@r9287
TCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTNT
+
#;#=F?*=F6?=E1#GE%4G,).?2H@-F/5)>+F?%060.4.(1(/D33113E'4CFE&*,G)76)0C9BA(!&+(G49)A357=):E*9((:C3E$1$@309!+A/F)2(*
@r9288
TGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAA
+
6$*F=>5-5*4-%%=!04@-$@("D%5/@;6(7%?2!":$<+<$<<-8G.%'7<8%#3:F!"0
@r9289
NTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATNAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATANGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTANCTTAAAAGAGATATCCTGTGTTG
+
!>,;<,>0?/!<!*),B#&#H6?&./3&#2$+@3>60/2#5,ED="E,-FDE468EB$'4=/EF#(%?"$"0#'!=?*!,<3'-G;%;&>:')2B47HB!B=BD0G;-<:"&+=*7G2?(.3D7.:@$4B('F9+=GGH"'*'=4(%<3.#4+7'?HD!E@E?F04@3-09<2'6H1:6@?='0,B8=7914B"91F>%/"D),:50B4<<C-7:
@r9290
NTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTGCGTGT
+
#+)&)***&)!")"*$"%+%#*(('!!&)"(&+&+%&*&'"
@r9291
CACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCT
+
(H>),A!?,+(0>$E)3&G%"34.0+*+'(;5/1>G0>:!$9C&%*H@)C43)4+$$*;4+B)31E5:FBCD;=&:
@r9292
NGAAAGGCCGGGGAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATNNCGCCTACCCG
+
!$>20B6#9>)A7(GF-?B)50#;.<>G.$+,24A#<4"A+-022$=%D*6.:>!E@"3@7*5106
@r9293
CGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCC
+
7=-D$9>7B,E(,)05$58C+=;+:C!%'#,.8D8)>F,<B65FD/$7',/9:FB?9-HD0H*B+%2@/4?$?76$HED
@r9294
ACACAGCGGAACTTATGAATCGTCCNCTTCGGGCAGACCAGCCACCACGG
+
C%1(@;8:!-:-&5DB&D8AF&E1+C>5506-A%383>9371?-/06,$.
@r9295
NATTTCAGCATCNCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTANCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCNCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTT
+
%,$/+-#'C:3B1;C*!7+H*97+A<'&>&:#G%29BF-.$HGH+>5HA<B0/$G1F?6@("-A59A29@=9=,/C&85C*8%H4;(3)C>>A,>F;';G#)==2.3F1E/$?34H<2F=*!B07<..B6(%H7;B+)8&=*$</>+-)#&-#$=929$92'?47@(0F+>;A>)&EG5<;F!@5&9(2E3:B6:#",8$;9."G(*B3C)"+>8!%FG6&+-BA%.+,.F
@r9296
TTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTC
+
83=G3H7F:#0GDCB,?AH$:0,AE&#B(;*;E!+C@#C*2+&.56E-7F3G"'D2=B.F$-6;@0"#1GB4"F,CB'
@r9297
CAGTTCCGGATGGTCAGCCCGGAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATG
+
6/+0)6+3;8;B&!&2*:$$?93A#-*#+>2B:!E5%4G1:A'(G"<EFBCA.@@47/,%'H:>%@?7'>*"?F8/<915,HE6A8%F*'$&5B4,B2(<AH?>*:H53:2:%6(0C3/C/;%6$&97#<!;%H4/*=A?<@"<?*3=745=39$
@r9298
CTTCCGATTAGAAACGTCAGGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGANAATGTCGCCCCAAGACCA
+
D-HG0$0&(+9H'("%B*>3*8&/B$---!@&/?:582;+'A%(/($*A18.<9.!D7)B+-3A8!"*3*D5H7F7D4$')
@r9299
CTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGGGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTA
+
@:8,.)=64#),6*'=A>%%E6-C$'!BH*EG8.B5/.3(=@B3+8E3=-62?59*%'"$5F@%"85)5,'H6A+"=?1=*,686+A1HH9;70">"4H7
@r9300
TAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTG
+
A?%4!&;9&9<9$%3/FED*B1"5EA0-%#!$$?BA)-7,+&CFE25@?4'-%"?A%(&?DH=:9
@r9301
ACNTTACCCAACCCACCTGGTCACGCACTGTTAAGTCGCTGTATGAC
+
'(!*++('*+*'')&!'$&*#&+)!+%+#(%')(&**&#("'#"&'$
@r9302
NGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTT
+
%?&-50/G!DH0FB?3;;&B<=2ED>+)3>7/#C-'7$4(B>+%)B%8B=%-283($B$/$
@r9303
CGTAACGGGCAATGGCCTGCGTAACTTCAACAAGCTCTGTCGCCGTCTCCCAGCNGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCAT
+
*H'/'(,1;AD@4"F.(594?G7>0F-A-,=3F&'D!#6:7AH0E9(A':*-?C$&?/(5?4G><B67D@3$3$3)"9$:-8C,=C<*.)
@r9304
NAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACANTAGCCTGCGGGCAAAAGATGAGGCCGGAG
+
'B!%64-+;B;@&75G5+2?:=!':,669H7.;4#A$.DE/./B$'=)2.D;4$=>'#,F8$9D&E#%CF@G$'=(52>G+(;<7/4'7:D4)/
@r9305
TATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCANCTCGTTGAAGACCATCGGGGTAAAA
+
0&:)=#$04<C'09E171.0.H,7!<FB>73<$,)$C72*+9>31B@)-'%()GG!+=FF(6?**-%"27@>2DB*G
@r9306
CGCGGCAATTTCACCAATCAAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCC
+
EE6@&/3;*>/+F&583*;F>?/0262EE8-F("6<.4:5;#-/9:D&%5)G)D<F>+$)5
@r9307
GCCGCCTTTACAATGTCCCCGACGATTTTTTCAGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGC
+
$H+<3:<:2(C$286>=?#0B50/<!.=$9$E;.5/<=90D5&6$:F"G+'&:+AG3#7'&7>3#C@2=D4/806<7;,>%&?GD!5#?*(H&30C?$(:3?)#0>1HC!)#9+2A(95!HE(?4CBC7FH+264E%$@>?'%;<;>2/E4B*0,8+E4B%322--%
@r9308
TAGTGANACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTT
+
;23$7$"H)77;&:(:6;$@,B9;2<;1,F,>"!&'B<01)'001+H)1F&$@:*)-+8/1E+51G9,;(#B,7CG2#>$85)(=A'A0+?-,:-@(F3.C69*&@4)-9:(*36,%>=)/AC<6;#G";0+7%%E+>F8F;1.A6!)3"%<$:)<?,77F92#)$("H7F1?.53
@r9309
GGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAGATCTTTACTGCCATATTCACCCNACAAAAAAGCCCACCGNTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGANG
+
E!3($40/4GB5:@*<54=D("H<!,#>8":"E/#+<+<'-1#.9*?8+B8)3/<1A8#1G=A*='G35:;7>+<2=@C"B"/1,A,F&6H+1/'=/:&)6/,;GC--FG'6%$/D=E8='H9.#),+7+5*C><8*#&/8-%%$GEE86'=64=,)%>=>/4($.;E4?
@r9310
CCTNAANNTAGTGCATNCCGTTTAGCTGAAACGACATACATTGCAAGG
+
%!$&(%$!")%#"!((#)%%+"(&*#$!)+'+**'%'")%#"*%$$$"
@r9311
GTATCNGTTNNGTTTAGNGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCA
+
)*%('%%%&%%'**%"$""+'+%#)##%$(*"+"%'"!'"'))"'+))!&"'&'"(+'(''+&
@r9312
TCACCTCCTGCTCCGGNTCGGNGTAACTGTTTCCGTTGACGAAGTTCA
+
)@2'&7/"A%=DH/B&9+9??A18C4CA>EC83=43B&C<@(:,B?;G
@r9313
TTCTGCCAGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCNAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTA
+
8(HB:F"G>>!E&/34+/0@"26C!2/"<$"'2&=>G>8,E=1G@(7#G(A;E*="B#9)!>*-:"H>C9,/<C4=6<4>C9>4+C2)20,G$F5(,(&G+A*"*9<->4$*1+=G>/!&(D#:=-5.,26#0D!DD@!,506272B49(1$-D:.6.E=>1>E'C*2G&#1/=&
@r9314
ATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCNCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGT
+
<ADG68-C456;*8C!#$-(!$D)(:D:,@"G)@*>2<*C3H$(D4HD*0?C@*'&4D-C&'C,4.=</<F=>B348C*;=?(DH122@,#AE-C751//&+H#+.47-A'!,E/62$/#-<E?2'6E
@r9315
GNCATNGGGGTGATGTGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGT
+
$""(&#*+'(")"*+%"+$$"*!!"!!)&$(!&*&)!%!$*"%"*&))''*$(+)%+*&&(&$%&)#(%"()%)!&#&$&&*#"$'#&&#$+*)"*)'%'(())((#
@r9316
AANNNGACCNNNGAANANNAANNANNCNAANTCNNGNCCCGGNNNTCN
+
$#!$!##$$"!#$#!!$!"$$"$"#!$!""#"$$"##$$#$"!$#$##
@r9317
ACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTG
+
)<'B/@G34CG(BB(109406.A6B18(H##>/2-"'E'%'DG/"5+9(!
@r9318
ATCCTTTTTCGCCGCCGCCATCAGCGNGTTGTAATCCGCCTGCAGG
+
F#>)=FA.-;H8E-?9'GH3+@A>*'D=&4GF4.C''1$A!?4;=!
@r9319
GTATTATGTAGTCTGTTTNTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACTANGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTNATTTCAGTTTAGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGTAAAGATGTT
+
&+!##%*+*'++!%%%"#!!'#!!!%+'#(""&&&*%)))#$!*"#")$%*#!)('!'&%)$##&'%)%("&)*&%(!%'*+"+&$*%%%$#!"#!"($&(")$*'+#$$&#+)&&!(%$*$"$!"&%%'$%')"*'(&*"+*%#)*+!'(&)('$++++)+$%"&%"''*+%($+()'$#)($)'+")!"$*++#(*"(+"$((&)*#!($"+)!*)($(+*%*%'$&&&+()(!+!#)!))$!%()#'(#%**
@r9320
ATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCG
+
A9FB5F8@/G..7"'C:7'G6;%G$C',%2FHA@@$>GF,))'AG3?=+:+">$+&#1B""?*"9B'"G#%0C!?E9'CC5.+.8H6?5F0,B9'>A%B!=,23C&1%&D52CF1AG590H.,C%A4H@0;1:"9
@r9321
TTGCTGGCTGCCGTTCCGAATCTTTACTTGAACGCATCACCCGTAAATTANGTNACGG
+
:#0#DE*&7#&@$#79,!H;C.,DD2):F,;88=,-=C7532FH(6A,&0#%&*!$A=
@r9322
NATCCTCTCCGGATAAGGCACGGGCGTAANCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCNCGC
+
"+)$+%""*(&$"*&+("!%*"*&*&+##$+')"%#*+"%'("&$!)&"#**&%"##'%!'%"))'()*+%&&&'""%&*&#
@r9323
CATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGTGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTC
+
**+&%&!$'!)!%(*&*'!%)'%!+#)"++&$&!&'%(&$%#"!%(&$'*"'#')#!""")$$(%'*')%+('$$%"&!))"#&')!"
@r9324
CTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTG
+
+$+*)(*))#(!"$"*##&*'$)*'#()(!%++'&!(*#!%)
@r9325
TATANNANCAGCTTNCNGAACTCGATGTGTTCCGTGGCAGGGTCAGCAGTATCGGTAAGGCGGTG
+
)&&*$$)$*#&&$#"*!+#)%#'")&)%)"++'"&$%#!)$))"!'!'!&("*+#&&'(%$"#'(
@r9326
CTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATG
+
D3B,E"CC1#EB7<''=%%GA=%'@GF&+'-(-EA)4.=*7(B0
@r9327
TCNCNGCCNGNGGCGNTGANACNNCNTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCNTNNTGGCACAGAGTACGNCAGACGCGAAGAAATCA
+
''"*!*&*"&()'!#))(''"'#)(#%*+*$!#*&"$!'(!"+'*$$")""%*(!)!&!())#)))(!$)&#%+%)$&')"*'%''%#!')+))#$$$%
@r9328
GTATTTCCTTCAAACTTTGCCACNCCACGGTATTTCCCCNATACCTTGTGTGCAAATTGCAT
+
+#3"36H!2"))!D4!426"<96D1(?)6$B->@?D.,/5F#247"9*,$2)(?01;*-(8%
@r9329
ATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGA
+
:C)C;1#?$CG.>D50=6.+@1:F8&GH1?;.),+!HD$CCHH)B3
@r9330
CTCTTTCAGGCGGCGGGTCTGGTCATCNAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTG
+
0,17.C@0*>$H45;BG<B6,+7%3<B+=E#*><@18!5$-B992&E;B@<0<+*!&+33)C4;H,FDF@+B(*,;9><=H+@+,1/*G9
@r9331
CTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCCGCAAGTGGGGGACAGCAGAAGACCTGACCGCNGCAGAGTGGATGTTTG
+
+?GE6G:7+2&6/(B)9/29B<:&*1<<>EE/3<EBA,9@+G83F(D<&7-B/3*:>:F2'F1F.HAD!&(68+23'./D:#>:'5+9
@r9332
GAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGA
+
3,*(#%AE8,7%+(AF32,HCE/'8GC47/5?-$D+@<"<+/-C+H?$B?>%
@r9333
GANAATGCCNGCGTCANACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGA
+
)#"+%++%)"&*(#"'(%)($)!")!&($(&&+%()%($'$&)%&"#"%$!*%!$()"&#!%%#&)#%*'&#*&(*'("
@r9334
AGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGA
+
5H%2$0"(>**42!)"&+A6;.C)+5#E1B6H>6%A"8B1?0.+3"H.C(+<C0$6
@r9335
TNCGACAGGTTACAAATGCATACACCATAGGTGTGGTTTAATTTGNTGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGT
+
'!(*+#)"&%"!&'%&!+''%$%!*+#"*!!!*)*!#'+)&%!(++%&!"!#("'#*"!'*+$&++!"$!!"#&$"##&)$!"'')&)"+'"*")!$#+&#+%"$+
@r9336
TATGGNACCCAATATCGNCNNTTNNNNTAACNCCANACAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCAT
+
&$$%'""##*%'('")('#""'"%$"#!#)*"$*"")+#*!&+#((("&#$!!!$'"$!$(")(#(#"$$'&)#''%((%$+$$'$*'!*)"*!!'&+"**+)!(*')%((
@r9337
NGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAA
+
#--,0",'G)AG0?8$>C*71;G52>F@7)'792//B/33E;1G(2<':.''FG9$;<8%"E=
@r9338
CAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGAT
+
G/6/=3',C<+F3D+/.B2$91<4!D4C&/7B-ABH3@>%'<=-8:&#H8;*:+F=G?#67CG"!*5(E"7F#75>5:935<(2:19%A);G,A5;;5D6G2?86@-@:):1)>?88C=5CDH5?=-42-"
@r9339
GGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAAAGTCGGAGAGCCTTCCTGTTCAA
+
/@+/:,*EH1!2@)E(?2+@,5GC.9%9B)&=83E2E4:GC2DH':@%/;=/!;%G=)$5)F9+,;HF2+1?"9#0?'38C4/8#
@r9340
CCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCT
+
G!+(?'.H2?-=B*3$*C,%&@E@--?9#4,"DBD4'16@5-"4*:3/4)E2<81A?6!A9B=
@r9341
ANCCTAACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTNGGTG
+
!"*$*$)+"+%%"&+))+(!%*)""%'%+(*$#*()$)(%*('$"+"'$))&#+
@r9342
GCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGACGG
+
$>$,)&%::D=$2-#,8C'0$C"F>C('449(F?23G"?=+)(-'+7883,:,E2)-16B1"46+4"%1>'F2>8<,H?/)E65.D#2%)0,=HA@7=F7:'6#%DF47G0#/E@2D@*+E91*3&A=.04G)#>D'4$(F3+@39#*/>G@)620E.(;C$F#CC'5>+:2.0==<195C),FH*0/A@63"@$F?#@/
@r9343
ACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCNAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGA
+
0',5E1<'FE:@+FB$6&.D>,'6H!.71")'&@?2"/@.:95%>*H8D5+0)&8<!B06'%65?7C8*8!%=6071G99CH,G--7E=1$B77:/A721A"8>5-1>==C3D<@&5(:./D$CE7A!8.!G,#F7>625B'H6#47G'@8,9@B+F;9+;&3;,+$,88H*?94'?+)6@@E289=AHC?3*;E;#G(&+-.:($"E2..4EB!35:2/+#AFA"<2-%
@r9344
GACGGNTTCNNNNTTGGAGANGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGC
+
#**)'!%)(!""**'#$%$'!(*+&!$%!"'##!)"#)("!*$'((+%)%#)%&)+'"#$+&&($
@r9345
TGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATCGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACNGAAAATCCCACTGGACAGTCCGGCACTGACCGGAACGCCA
+
<E$C9:CDB52=(<%H8+-)9,D9B!3HB/&6,#'",7=.$F+)4=6<4'#@F?0<.,89?*=41C>&+2+%;AG=0GHD(6&<@*"=E!9"/&;;$66F)G2160(06<!%15#/*&=0=
@r9346
GACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCNCCTGTAATGCGTACCTGACCACACAGCGTANGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGA
+
-6D<#?3/E?44F3$3-&EE*.&"3<-!31F2.4>A4D.-4D=+;,D"8'DF40>,)/@<!FHH4,"-+H9,+:G>,9:>=&3H/6#D<%D07.9/''$4E=52G==4/)F,447#H6%(72@G$D<*$GD82(9($4>C)BD$'$C391;/"'H=A%2A5D):'EGD:;!45
@r9347
AATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGA
+
1(12@)CF%580#,FD8$""3:8H<'(A'3,"1'E*2>.308E3<.:7A523<6F&>)7=2)%7FC<6(D/"%B/;B1G9;%0/<A2H8?4%*F/!F>,,><0988&@#71,<24<+
@r9348
NAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCC
+
"&HE@#54B**%8;7!"&:*>@80F:A#,7(-,&3H%2G'/1!)87>16C-"#/<*>?>E4!.>GD'%8CH>46.11>1!H3G!->E:C%?;::9*&?9<2G)-)@.D5
@r9349
TCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAANCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTNATTCACCACTGAAAGCACAGCGGCTGGCTGNGGAGATAAATAATAAA
+
6.),/,)1E00$>8@ECA>D&=AAD(878D.CA(2A.GG=*&1,"5$?(*&>76-&0B%&0G.<4)&2;2'1!*BGH?4-F<.#G,3F>)B?9-<B,=?$033FF)-D/*8A>!<94C&2B0$/(!(953*G,6$5=@'A0C$%*F?+@C6$4C006(,AC%5F2@F(/C&-FEB2C*2*<!%->,!5':=@'<#8"5?%44#-720*;9
@r9350
GGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCAC
+
?D;7+(&)FB"@A"!G4'"1%A3D8G"8HF*;)/?./18C%
@r9351
TCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGT
+
/&!>#,772</*C7#1+60&418:5A(".58=;!/.!*97E+"/8<:.6:7.&F6F62&CB)2C(2@?#:;99FB@@1
@r9352
CAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCNGC
+
#8>3/B"68*>F?G5+C++9$+:H906D/!;,H.E!"7&5'?3EB1#?A#>
@r9353
CTACACGAACCTGNTGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTNTCNCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGC
+
)+(#$"*'%&"$)')""'%$$($!+#(+#)'$$&%!')+*!()!!###("&+)"*#%")!"#*))'!!$'*$##+!%'')*&)!#+"&*%)'$"!)()##"(!%$)"&&
@r9354
GTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGNTGAAGCCGGNGCATTGCAGGCGGCGAACGAGGCCGCANCGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCACGTGGGATGCGGTGCT
+
6G>3F7@0$?G'+<CF-A>7=,:H&#'F==B4%DBA?5;H;!;@<=<(8&-='E353/D&>2B5:76AA+G29#C*;:HHFBEGG;F@-D(AB,.?D$-G65)F6G;6)<G1FC52)3-,2CA9C*).@@<(H>!25C-&69/"=&G$(H-6)A30<58#.!%FD+!;1A:42H7?#5-:/@90#'-C!=D="659E
@r9355
ATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGNTGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGC
+
(1*F0&&9:A7.%'!3A1#,#@65?=A6=:=E;*CF.=-+?B>8=H,AG;@;9.C1A:!*-'&*@31'B%443B-D.8";:F393@7CE'=CD?14%9("1G/4F)!$5#;''!.=2367C.%,,=D.#*H*'C+ED1@->HDE"E3)AD)C"D0#D-@C,*-*)C@A+=103#(#;50GF%BD/<>++!6A/895EF,##8*(,1@;59C%-!((,"'/8#%2&(9'?G%./H$-FGC&/,+=43A3<*
@r9356
TGCCGCCGCAATGGCTATTGGGGGCCAACCGCGTTGCTTCATCCGCGA
+
C',@!<)6D&+'(3=H:(&0"'A00B=,C934=<=0<AF%,)/=C"E:
@r9357
GAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCAC
+
&;!()F$.?A3@FEA>;*G/D>0E'9D-?-7'&:3HD'.4<0(6"D*5*-#2*
@r9358
TAATGGTGCGGGTGATCGGCGTGTCATATNTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCG
+
;<=(F:;:991;<7?#<46EF>E1.'4D3093()(!1?)57".-.F>;E"$*@./"@,-566<1D:;="F&)B*?0D#@)#
@r9359
AAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCA
+
$A7C52E,:81*?101.D<7:,==>G'/EF5E!6'?='#.@?<AC>?EG;@GF5E=/G,C<#BE+C#
@r9360
TATGATCCTGATGTAGCTGGATGGCGTTGGCGGCATAGCTGTTATTGCGTACCAG
+
,*<2)$<B"32<@4-CG0:5!2=H%%C8"+/<1.EH*7(D?'AG(&(G#-:6:H6
@r9361
TTCNCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGGACC
+
%*F1*F#=8=9GF(#CD242D55*61>!=98+4E%(4A)#-*!#*)+7F1.HC(:
@r9362
TTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCANGAGGG
+
#<%%?59$HF'>93>>!?<3;1')C"->805/,A*@.4++A!<<04B&"
@r9363
CCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCG
+
=@*8?!H7::%)D/'4!)45G.4./8)A<,4+8G'A4.G?B#F@,;$H(EAGE!6%>E56<77&&&/!G6,@
@r9364
GTCCATGCCNTCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGANCTNCGCATCGCTGGCATCACCT
+
1/?2B;>@,,D1$0)H1B"*)!*E/$BE;,F$*5G,@-A:+45!;!*&:>A%*/CCGAF/C$:C=.5*$5*6963:#&./5-34$(C;>%!09@BB$F4(9.3A?*&4G#=A&#/B>>45-("E64DD8=)+8.=62@9D.H':!,,DB<+&##2220:()'=59G"(F@G/;C%=:"A-.
@r9365
CTGGGGAATGAGTTGCAATNATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGT
+
F:#1/-C*$%)+0<E,H"%011;*.!7G2:FF?E@4D+7C5H0%A.!D89=>%)@3#!95;D#+$'0*)->5F.#92B+#B"6AB9
@r9366
TGGTGTGGACATTTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCA
+
-=CFB;0G9@-*/!")=#,)C6&E""0;E7456C($9EGF4>&G!&=7:/AA
@r9367
CGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACC
+
D(7"6%=,10G-A,-36G#D.!1%5><%>B0A6)E,G>CD/4=B7%F4)<D&#'7H*6@*7G;6*<$-@*79#:,B0*)?8,0%
@r9368
GTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATNTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCT
+
*(%=EG,$:65C#4$/!@1-55"B)$%BC@4%AD&!"#E$/-'93+-,#93):/=4,HG<B+?117/4%3,A0;E$75<,#)C#+!8H:4>99:))DG=E.!HE8@&79>8+B@-1
@r9369
TTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCA
+
(6"C&=E%:G+F"GH+%D?82#>%<=EG!0**'9A'60=5@:'G7H
@r9370
GTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTGGCCCNCAATGGCCATTGCGGCGGCANCAGGCACCGCCGNTTTGCTGATACGGCTGAAGTTTTCAACGGCCTGCTCAAGACCTTTT
+
F-.",5C18:C5"/@G$,-*0EF8$-1;,&6"1F'<1@5D7*B>5>5..$94D@/7H(%+F;(2&H/98.A*G+(69>"*G)="'2/!(A,5F<3?>.FH95%"88-%,$H?"./7F:@.<0#"8!7=184D>HG%)B%57DF
@r9371
ACAGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGC
+
%'$B6A50-?"A@G=$A,-=+9(H1A,,.""!$55H".5&C=1"
@r9372
GCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAATACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTGNCTGCGGGCCC
+
$G9'6.(<B+B#0*%<88)!4-%-G14G?'#2B'/:+-EB(@)>G<(.)6,8(1GH1%!@A12:9&(2"F,A%G9*4H43D06")D1A!065,9-+./7?G4!'
@r9373
CTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCC
+
F+$4:!H0=#!=0$,07%5F"(05>C.CH14/0*:C@5A+&C4/D%:6;7&H&>6..F<;;$"'$52+1<7>D;)<09)(5(<@D;9=7';<7'E'
@r9374
NCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAA
+
():8(%$.19D'=33#7+3)E':58<G63C5B#);&F!8D2CD7(4F%A5=?6*#F$03G/
@r9375
CATCATCGTCGCGCCGGTAGTCATAGCCGCTNGCCACCATACT
+
5D!B<'.:'6$H-;#,<.B>#<2,):C/:3'E?7=F/9:;E4#
@r9376
GACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTACATTAGAAAAGCTTTATGAAAATAATCTCCGNGATAAAAACAAACCCGCTAGAACAT
+
-'5(F!,A"D7H*19D991-C0&33'-G:;888D;D*:=;9B(=816/E)@)>$;'/4%5-!593%;3@,-.5%502=!:G4B7>-(<&G7)&#<7=?@.,57E>D94B9<5DA!=%@B;H>(3B#)3/%.+,!<A>
@r9377
TACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTACTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCC
+
='C5"C2&3"33.77?@A3,8941=$$?%?D7A9C=710!-?8DE<<"'1/=<9(@A!H;GE>A717)B4$**6-9HD>?(8'*2'HGBG246F'&
@r9378
ATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAAC
+
*+!((&"#)(&$$(((%"!($"%+("(!*!&&#($'%(*')%)
@r9379
GNCNTNANNNNGGTGTTTTAACTCGTGAGGTGTTTTTACTTGA
+
(%!*!%%!##"(+"%$+$)&*%+&%$)&$$"((&*!!+(#!''
@r9380
AACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCNCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCC
+
$)H5@/*2<?.=/#61-".)*+"E-B,$536'"7C**!+/4'1<)4)83*3=FAAA:0EG4F3DAE6?!3(%C)GE
@r9381
ATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCAT
+
<G9";+:.6"&>F+@C@)188+2,'189A=HD)G&BB&/"F(D45'9-,8176DE"5!,,10;$,*%C5H@=1A5%)+<!,
@r9382
ATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGGTGTATCAGGTGCCGTTGTCAGCGG
+
-.2;A-G2B05"?F;AD2'@4,7+(@B'.<',A,3F)+5+7DAC0<&97GG-(E#;+H>@0@#<C13<?E+/01#HF&B-97!>H!B5&D'&+H=3D/!27=-
@r9383
TCNATCNCATCCNACGGATGCTCTTCGATTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGA
+
')$**(&&%'''!!$)+&'!'%$))!*%!+!$""%(+"*)#%#("%%"%#(%+$$*'"!())$(+'')$$*$((%"*+!()!+#%&$!!$)&"'$*%'(+%%$&!)%%($!!%"%!"($+*&+(&"&!*"(&))")"#
@r9384
ATGACCAGCCAACGTCCGATATCACGAAGGATNAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACT
+
C4A".:=FCG@5CH#".&,11,<FG(?G>)!:H"#9H,!#2*48B!D#'"CF-"1$F!;5%%%F&->(0BE/643,(2&DG)%H5A>("<=2@.$1@5)=1<(C@B95*!9%
@r9385
CTGCAGNATTTGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTT
+
"@<'%A@%1AA-2358E=.?1=B*00,(C#!5+%D1+0C80F0-=4-.1>$"($C4/(B9+1"$5"/06.4,/6&1B4&'HC<5D
@r9386
ATTAAAATAACCGCAANTTATTTGGCGGCAACACAGGATCNCTCTTTTAAGTTACTCTC
+
EH!6+(3/ACH2,)D&@).&#D!9D39$=B90HA.*&).H()=+D>">&#'3A/B,;F;
@r9387
CGCATNCTTCGGTTGTTTACCNGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGNGGTGTTCGCAATCTGGGTANTGTTTGTTCCCCTGAGCGCGGNTGG
+
)(++'(#!$'*''*%$)+$!+*)!!!'+&$'&)'%$)((!'+#"+$'%((!*)!)!&+#%$"''!+***)+'"#"#+$+(&$""""*"""("%)(#)!#%$%$)++%))*'(+%""%*$)%!')'))"($!!*'"*%")$$+%*)*%#)%"(!&%$#&)$'*'"()$+'(#+$&%"#'#+#'$'$$#!#+'#'(%
@r9388
GTAATGTAGATGGTCATCTTTTAACTCCATATACCGACAATACCCGTTTCATCGNGGCACTNTGGCGACACTCCTTAAAAACCAGG
+
E"A?=C.1!!A4*<,7H>"@:A!&32-1/>18>@@E.;-,@"E!?'-&*;A-%.+#%=0'?<=1@)H*C9>C7=='E>.#G9B(!8
@r9389
AGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGG
+
57$4FH!C=G3BB-B$A;4=;5C625<'>-&?-1D7;ED!89;+/#":06C+/%>8:)*<+%2,?F#
@r9390
GATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAA
+
2".2-9+D7EG@%0.84F<ED&%HE"1B?,65$(6<7D:1.")
@r9391
TGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCG
+
CC1*)25:7B3.0B+@09,,0>G!2@#<=4D37"5'/7>0%-))+3H:!2%<!(1@=1)&H8!/%C9$/*2C!D@85'))%!D&/49
@r9392
ANCAACGGGAAAGAAGCTGGTAGCGTCNGGCGCCTGTTGATTT
+
($@6"6/,;0#')#:.6E!@(AA:/-/*+BDF."<*/&+*$5#
@r9393
CTTTCNTNTNCGNATNGTACATGNGATCCTTTTACTCCTCCTAAAGANCAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGNTCTCCGCTTAGAATTCATTNCAGCATTTATTGGTTGT
+
!(*)'#$!%()*'"&!'(#!*#!&+*"'%#%'""!*##$$$*&')!%))&*!'#"'%)%!()!%%&+#*'$%'+%+*&$&*+")"+*+")))%""!$&*))")""(#(##(%(+)''+&&!$"$%%")$%(&!&!(+*+'($+!"'"*"$*(''$"$#+"#&"&(&'"
@r9394
ANCACGCTGACCGTGGCCTTCCAGCNGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGNGTCTGCGGATA
+
"!++#)($+#&"&&#(#')%*'&$(()#"$"'#!"))')!+)+($*)'%#)%#''('*(!&))*!*+'#*
@r9395
CCCTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGNTCTGTACCGAATGCCTGTATAAGCCCTAATAGCTCC
+
&FE-2:H1#0;H%!+D1@@H'0+%4D&,!3;7<)-D(@3"5(H!+971#50F$F!EH6)G2>5C#368!=#!&=,>:F3,<F)*<EF1-5H#-9
@r9396
GCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGNTTTCTCTCATCTGCTTCTGCTTTCGCC
+
5*3A20B8C@/@))'E"&817@8;=7)804*&/"$/8G)@&@7*#!!"A4<&.1E"HA2@3)==1
@r9397
TATCGCNAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCANAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGNGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAANATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTTCAGGTTGGCTCCAATTATTTGTATATTCATATAANATCGATGGAAAAACTTTTCTCTATACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCA
+
#6F"G7925"E=(C59F9F)5905(B,&!G7*$-.?6@(-E;;&(856&6@40->'#:,F<>7G44/(%7(15$68##<+.2-)7&EE<0!2.,<@F!HD3/2054!F;)8"8$"'HCHB=;C0%B;4&#<6!;)'*')5&:@92!/&<'7%?-C.62;0)9A225'G//35@D)<3&$&+5=:H+A%H7*AGH6(A#5E-G*>+F'4B(8A%?.1#("""6+,'./*4E,)<15.*:C:#24*H65"1@8&"$6$:D>C@C3H=./F'1C2D64#&".>@&$1E3<,2/D=7"*C=?F<>>A%5:&>DHH=%0*G=25.?HAD"7(FB;<F0**9>255;HHB<@?F?.9.!=8=!B8;2*$54.406=@(;??B6"!>5>7/5">G)B;!";3B90C<<:"?AG8@,<,>
@r9398
ATATCCTGNANCAGTTCACCACCTGTTCAAACTNTGCGCTGAACT
+
D!DABA=%23:%G%$/@0@5#!<8=0%':+!?<),33HFB&H/!;
@r9399
TGGCGCANCNAAATNGNNCAGCCTCGCAGACCNTAAATNGNNT
+
*(!')%'"#'')'%*'"#&&&&""&*()'()%!)!%&*%%&$'
@r9400
GTACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATNTTAATGAGAGAATAGGTATTCCTCATGTGTGGCATGTNTTCGTCTTTGCTCTTGCATTTTCGCTAGCAA
+
&#+(!#'$&'$*#!$%#!%$*&%("#'!"(+(")*+!+#)")++%)+''$%'%%!#+('(*'(&**)(!)'$"$%*&%()#*%)&$&$))*'&!!(&)(+*'+)#%%''*#$!#!%%($''$**'')#"#!(&$(&#')&*)"%&%(%!!%!)*!+%$&%"'((*#('!
@r9401
CCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGTGACATACTGTCCGTG
+
45"E!;+/6'99FA#.66--:7FE$;F5-?66;A,:90;*':@>>D'>6*37&;("GF2)7(1#$9<)3?,!-?D.'E%3(%%/
@r9402
NCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAA
+
!3!4G0&"B8?B:4D8H&'G#FH6A8/#/C":*G*+!$E.();*2G0>>6!;4C'"3+4>C3%7<3%&#)8F"49'!8?"'/7%824=F2)@C;B8=BE$7A:8D%?&,*;$8/F?"C&'F'2)8)@9"A-1>;9'"+FC:D%=2H#B0"".6.**"0:@#9?-2A&H3G2"2((.=B-!<.!9B
@r9403
ATTNTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCNATTTGAGGGATGTTTTATCCCTCGTTTTAG
+
6;9'#,F3DD":1-'#17B$A:4:;->H8&(7(;@-?!37)*?!<+GF"C$-G#";6#&%8<A$B>04'D'/*!;#*!*?%9E=DCF>(D+5/4H-'2('476ED5=CD.E>7
@r9404
NCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGG
+
$2A9H&6&=.@@;E4@$+<:62;.:1;=-,:;3B:@&11$%%311*,8-';24F0""84
@r9405
CGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGAC
+
F2$"*4$H&2HB$<'F580?7B>-#-2?$3.4G6>2F21D21%$=-F')=#8%@>"*+4!56/
@r9406
CCGCGCTGATAAGCCTGGTTTACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCA
+
F=4G/C?=4$()7!1C)6**4H>$'')G76BGGB$AG"C@$*771*-,,@D?8;'
@r9407
CCCCTGGTTCAGAGNTNTACGTGGAAACCATGAGCAAATGATGATTNATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGG
+
D)/&<!674/8F-*<0$&.)1=9;:$*3A$6';,DE.$;7B?#-@?)2F8(:%FF(C:$GG@<-,/3>>%6@")!B+#*(1(*-/(>E#B8>","2
@r9408
CGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATTTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTAATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGT
+
HB88+;45$(<<A5!6+?G9#A<980<F<#F8GHC$H!@F8G93F3%(6>ED,.'7<G43,>/C##';6"9.G.565*4F?B6B%/,(D=##@@2?;1+,7!B>!3458%0A=&@5")@#;5!&3"52:/G(00=>-C+.069$1C:,>*8=..#9+'<CD9%H.%7B0/:%'H"'69D-*&&80B%$,,A6>H8GE@$@&H*59CDB+4.&"7#'#-4"<$2F)06AHD-"#6.#%8;8H)+(=D.6,5A(D':*3C/+!$*$<+!4-E!'2"$-8*>#E?'E$$'5=F%-(5G!E!.@/#&(>E9(?H;7&>CF'/)-3+:35"<"45FGF4()D.*G'*,8+!2EE/6?1&(.F:H#3-5(7/&9%-A8!A.(?D/+;(*D1>7+0;#1=>@&D3>G;&903-ED="F"&)H<$"C9D-312-6>%#C+2/>00?FE(9>%F?;+@-
@r9409
GGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACNGCCCGTCAGGAAGAACT
+
B=-)<7'H!-=B4?($;D(:$G8>6H'2C32>E<6*H!:/6&$&:3D-:33B=*&.6
@r9410
GCTGAAAATGATGCTCTGCGTGATGANGTTGCCGCTGGTTGTCGTCGGTTGCACATCAAAGCNG
+
0%5D$:="#?)E9"+24H'##=$?1@AH%1#C"#H&8D7,*48A">@94=(D+7,-=;E5%23!
@r9411
GACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGNAAGAGATGCGCTATTACGAAAAAATTGAATTT
+
HH.40<0(D:/)3614*70(E;E2($"8#01B*355D(">*0!#:3#CG5=94%@?*F203G1-B>$;!#<D=(=:(H:..:978/?@9(8
@r9412
NCANNNCGTCAAANAGCTCCCCTTCAATATCTGTTGCNCNTAAGACCTTTAATATCTCGCCAAATACAGGTAGCTTGGCTTCTACCCNCACCGTTGTTCNGCCGATGAAATGCATATGCATAA
+
%'(#*!+*#'*&#*)(#)+((""!+('%%#(&($&#$$"(#$$%%###&'#$'*!*!%"+*#*$!*&$#!%!#$*"#$%!&%"+(&$%"(&'$(+'$!*$'()(#&'!&)++#*+'#'$%!'*
@r9413
CATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGNGCCCCACGCTGACGCTTTCNAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTC
+
7;9269@>=);$8"'1-"GGF?B'2F3C7DCA$H44/#H"6<8"$67<4(D"/024'%H'?3,6,6+%51'CG469'$>*+B'H(E:A1#%-6=62?B0$8)$9F;$F+@%AFA1*%#
@r9414
CCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCNCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACNCCACCCTTCGTCCGTCTTTCTGTACTGNTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCT
+
.&D/)FH-<%6-B9>;CA3-)A9+-=#D#)C>01=7>G(D!/+5!B)>*9>!=88?0C%&:64;DD,.0G'C6:(/3F38-%+%#(74)G8=(!:?D:'+-4)6;,CC9E4($6!>%#1$.%?+B:>/*>?,$-*@%0*;B<F-G'D$%"H>):/:A.5D0F@,1*&9E%0/;*80>;&@*-7/!B2!7*6:8&3F44C?@3%2;AH$,=3?18>/G<<-*/C=1@D'8A"G!7C7C82CA5EG$*><>&)#-%8!>).@H0%C@;8;6:F,A=245#>9!16+<#,+
@r9415
GTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGC
+
8A%?/#(5.1<2(HAH><1:<BB-$E=D*:<;9?1%E(($.4D#9H"BE8GC0B5!-*'-H(-?C;A;)!38-.F
@r9416
NGAGNNGNAGGTNCTNCNTNTCGCGTCACTCATCNTCTCCGGATAAGGCACGGGCGTAATCTGCCANTGTTTTCTTGTTGGTTGCTGCACCATCCTCTNCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCTGGCGGNAAACACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTNATGCTGTCNCACAGTATTT
+
&&#("!%!&#*$'$"!(''+$'!+)!$'(+$'')&')+!+#"*$&*%"('$+#$!!*!)(*$!+"!%**(#++"&&+'(%!")&+%+'+(%+&)%((%&!$+#!$"'%)*')"'(''*"!%($'""&(!((&!*+**'&''!%))+#*###!$+$&+&)+**)&(*&*#%$!+*+*%''%$*%%!#))!+*'$&'&$'$*#%$%*&!+$#))$+)'"*&#+)"''&'")
@r9417
CCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGN
+
'AD'&/A9H(5H>43500C>BAC5H2.638?G2!5.3E7&CH</".7G7+5&&B'
@r9418
GTTTACTGTGGAAGACGCCATCAGAACCGGNGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTG
+
00?>!836;B<"A7.D>#8+47&8"H<7())338/92+%<2F22>F5#:=E94'E47C.0+>/@?9.:-<-<7#1"*BHB8%;?-=2AHB#%;F>6!<<(2D=)D,!)/5FB;6"B"<.0>9B.*C(5=.9?C664?>
@r9419
TGCTATAAGNAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTANTCAGAGTCTGACCAGAAATTATTAATATGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTC
+
5,F%$"F):#",7%36@9D.%@.(/A<85=)HGH)$35)@)?2"=5H.3"#)<!FF/77<-CHF(H4F?,2(=,E:$.$1@7@(H1;'B$4C;G%366AH41C/+$,6>>+"*/7*+<2%865=$$C9H>=6'/E/96.D%1;+B?E','
@r9420
TCTGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTG
+
*+0(7,E>:H=C44A.:'.;,H-%D,3:%CE3GD%D&75(('HF,!4?H0?@C>*-6)9/)2&+76-F,3@@G67=C:=742(B)HE-4H@,48#
@r9421
ANCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTNGGTCCTGCACGAACGTCAGC
+
*"+++"$!!"((*++*#%)$$"*'%$&'$*+#"#$&&"%('"%*+'("*%(*!)*&)'(#$'!&!*
@r9422
ACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATNAAGATGCCAGAAAAACATGACCNGTTGGCC
+
1H*!*,539-A2!$;E+F$):4@4:6+&)80$0$!0F>53>&D/%/H4G>."",/%C/C8)D603='CG,#-?>.0(8&G/.:DH28D,F0+;0>+4$@)H2G9+":-&%6F5(4>!A"D9#F9##G?.'BF?A.E
@r9423
AAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTAC
+
7;,E1-DC4##C>%&.D?=8&170C$CG(C"%!6#0<B<BA+)C@2509
@r9424
GCTGGAGGTCCAGCATCAGCGGGGTCATNGCAGGCGCTTTCGCACTCAATCCGCCGGGAGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTNCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTGAGCAAATCGTTAACGGCGTCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCA
+
:6$@G>$)<9$#4<DE2#E4%@!A*B7>?9/F!=#7+1D>>+F=!>+%2C"6?(<:.&7H>#F&2C=-*$C)(E--2?G<>3E<E&6B3A%(@"1B,6CA'5@?,%8*AF'-9;A*9,1,)+($9)'+>,.G#5;"-$-$?G@)/6%!(/'9FB0-&:*"G850>&:5'=7.#.'H/+AB:@30+E1<-<":G;(95*B37G?H8H!!'6>7"&9"6+'
@r9425
CCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTC
+
=.'=1:%::E0BFG*6..1>+'+44#$-=@C3-(E7%&G-DBH+?-*-)D')#()D6F.7G:+&#D#
@r9426
CANGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTC
+
%.:$7D!F?3*6<-$8#9G*<$:F<//,-:#0'8!!D*,.:!>5G%72-=5
@r9427
GGGGCTGGAGATCCTTTCNGTGGACGCCGCCTTATGAGTGGNGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCG
+
69A,.0#%7,(F@GF6)<%5E#3*@'3-/"=C5$B<'.-;9'EE,-F$G%'(:.9B-'!7!;,@9;(:+H??)-@=>1%
@r9428
NAANNANACTGNGCCGNNGCNACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGNCTTT
+
"%!#$'*+"*($'(*&!#(&"(&!$!$!**$+*')(+)&!(%&$*#+)%!!!%(((!''&+$&"*(
@r9429
NCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCAN
+
$=>'"@0C><CFG<C))C9!&0$$2?!9#ECGA5.72@#)-D84))-'-"2$3"D6!7&3!,
@r9430
CAGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCT
+
)#1>2E(%@#!1D:#?1!'H-/9"B?<#<"=7+!"-324)0.6H+"H56>;#*><4<?*'2B:5:0,)""58#D-1B0!*?*5'<<=3/D0G+);$4C%$!C?'8+F?;*8'68*$%@;&8=%)H?%+3*@,),("83++7%AH,7"
@r9431
CCCCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTG
+
78-%%9)+"@5)D/=4)1H(".E5''21)=%43!.3:>6=$#@HC
@r9432
ATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTANTTGATGAAGCC
+
3*+5!3"9H1@;H/"%4F!E2**9CG:*((@9"0=9B-53)D*>.E#:.3*6H(A638!+BB>5*&>:,)',?:@4@&8@?3-%.+>">>EE%"E+3445?(G7#,+E-$87?6C,7HE5)627);0!#+080,!6&<;7>E+!4EC.3$G=
@r9433
CNGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGAG
+
'!95DH8$BE9,HB>.H)5#F@#0?-:79"'73.G32$797B#95'/<-'7>7'3#/E4&C,4>28&75?89HF
@r9434
NATTANNGGCCGCNGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTC
+
!&)()%$%+%"!+)$'%*(&+#'(*")&!"))"'(''$++$+*++$+"*!&'&"(+'%(($
@r9435
TCGTCCACTTGAATCTGTGCTTCATTACGTCTTAACTCTTCATATTTAGA
+
%H%BA73CA!4B-2#097'#6H%4%<,);&/H9,E1B%C/1:+5$$2$,1
@r9436
ATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGTAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGC
+
BE5C(E@C@$-179>A6D!:&35-0'2/83">"7>*?4!)E!=CE/E&D*3&9A,A6(8:@0/<?G+&3)G;FB2,!0B>(E%;FH#;.H4D.B2!2;8#9;!/EA)=:0<)%)C/943E14/'&#%1.<&))"0*-<(&+-$9:BH*2>#)&#"'%C4$/7&>F#0*5+9E%61C57)
@r9437
ATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTT
+
8;/@:)!E3HC6*;%1D<0!<8)'H;D)@(:DH('#@:<:FH-%>/G4B+!-;.'$&&97?,F>)9BB045><029E#;#;B%%H(CC836$1D3(G#?04:,
@r9438
CTNTGACCCAGGCTGANAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAANCATTTGGTTAGGAAAGCGGATGTTG
+
*#!+#(*#$+!#*'+$%(&!'"!*$$)#'*"$&)*+$%&+$%*))+'#'')%'&%**$#)&''$'$()"$('$#(""%)$&&&+%((&!
@r9439
AGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTG
+
;#9@:0G"<#-3872#:9">(1C<+.49A(H/08&D/A3,H/;F/):GF=
@r9440
NNNNNGCNTGNATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATG
+
!"$!%*#&'"$+%+!'*+*%('$$#"*#"((!''(#+!(#&!++#'!##*+!()&'")&$%"(**'("!#+%%#%'&
@r9441
AAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTAT
+
21#8.6D)0A*$/833D3C&.G+(%>@/%<F/"8%,!H826#?8:7$=."6G/1&F'$FF,65H3,8)@1-
@r9442
GGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAG
+
9H<*(DH@.@E*F.0B-2>CA3%<F@:H0"$<'%27;@+$03A2H$.C:.B;)1>ABF'?!/0*"=,
@r9443
ACCGACATAACCGCCGGTGGGATAGCCGCGGATCAGCCGGTAAAGATTCCC
+
D$/:#8.=?%42,.//93!#$E?$(@@%8*2A3E+D""-55-7425#F1,B
@r9444
NTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGANGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCNCAGCAT
+
$1>D;>9491HF68!<0<(88:?'E5)=08+D(=+:5A%F((17-0HG$D.55HE)F;1::2@(5+#.%30H0&AG<D??04C"3(.+@@*A!F?0(+8%:;,!+F?)4'#.D!;9-0=0/3;$3<=5#)$8@(1HG5.:HD:40;;7G'=<B37+G')$H+5";<(:55><31$5G<%7-861>0:4GB&;-9AD&F$5B+"!%F*1@,D#/8'1),E+D<AD7#<9=5(""G$1A6;E!>'F9F%5-(*'/6540!GC@,C-G'2>6EF88."!C<8+,E9,4;!A2&
@r9445
AGCAGATATTTCTGGATATTGTCATAGAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCNTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTTCATATTTGAAAAGTTTTCATCACTACTTAGT
+
.HD30.*'A3;'(>?*14'##*#;,B<C?1AH#"4CD5"2;-4A@""DB<6D0"G01(3D>B&57$F=%)10F684/5A$$6C=.-'8$!0&F'#166#4:4&:H5.B;/FGF,AA;+$0-+B=!*1+-3'8';6=AC!-#!'6>-B
@r9446
TCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATNGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTTACAGCGATG
+
)84*C':AH8=<5.6*(7-154E(=7GE:A!/?53E8:G<)(DG,8BHBD:>1#D8:=-&F#8&985#</6+#<!(+;$A!H53)24-,$2B@H?+B.67D8@7,.*4/(A0?7*BC-128.4BH;?+-H48)->6"
@r9447
GTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACNGATGAACGGTGCGGTGATTTATGATGGCGCGGCGNACGAGGCGGTNCAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGT
+
03D:@&%0)"/2)++:1(%D*7F08((.A9,39'+-6=@C4B6/*2&&.(".&*G8C)6&@D?.)&2-/H&)228.%'F5@=1,;$DE,!=')*D,(<%6A#".6:1$=#!09-&>+='%-;<=<39;(5C"/>H+$0#8=%-,.<:>"*6?2.!'*!8'$-0.36FB='8+6:(+-8F;5%8))A"?2C%,-%$DH*C->F$*<A%&1:*5('?=:""*F:,??8*2%9#FH04?=F*2%.0B69=%%$B2)F.D)!,24<!@A?D>7A=(B!94G/,2D+6;7)F
@r9448
GTNGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTT
+
'($8&4*.?20;*C%;H':'=-DA?22@5E5*'?:-:34?+&)94144+.(,&(H$!2(<,*)#"D
@r9449
GTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTACCAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATNTTCATACAGNAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAG
+
%*FG)8..#A@'C000H:517?D:95HF'(4@8.3H"(BAH9#96DF!2&858)B#);<-5C.4!B%(B-?9=7,3!/80B)-#7&*<%*>:%0),>!,2*<?+,=D5DHC2DE?!E<5!'D,D1?6(#3!!=FF25,5!F=E"7($BH!!87,/B!'0$1&@+0#?'9*>D?FC+(".F-A,AB)?@=(6>*2=06G6%5"C1C6$E%<B?7C
@r9450
TTTATGATGGCGCGGCGAACGNGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCTCGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATNTGTGTATTGC
+
B%>5C5@5?')972?)>CE/*(;%C(C*5C%>>.4G'26H1D$1C+1B<=<#!9(H/*G+?.&/F&'4!03&*.A>@'5%+F>3'"$#B$6#*(H%%?:==8-+<$.*.@.72A(2>"9=B<=H*@C#A;H"@E,':A7B;3:E7#,7F'#-5+E%?$>*/;-$/!92E04!75E&#A&F0EB1+6)(A6*:"6@0B+H@#31/*342.@#AA-0!;?#GA28.,*#@0,+/:G@F!!"6/G/HE@=00@DA8=/).9?H<!D$=G)&(8#"4,4?71
@r9451
GATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGNCATCACAAGCCGGATTCGGTATGGCTGCGTTCTGCGGTAAGCACGAACGCAGCNAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCNGGGAAATACCGTGGTGTGGCA
+
,6&(.H8G:<*G'!*8,2C'?)8$24*!,,C-5C(<944D6B83+F(C:24;&B>F-C6>+!F0*2@BF8D$!7*$#'%?.D3>';@B55>=!3=;.*>;:6F971H21<B9%<???E!)>B8)'0&@?6;HD*/>*D0+>2!>-2<=F6;(/$4?C;D"HC$5"".$(F5<H&9G#5<>@H7==D!A+.C8?8H2#)7+=AE+G,?7
@r9452
ACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATG
+
8;4AD9&%%&*'!G=$758?#1<D-2*!!***';C27(67(B
@r9453
CGTGGAGTAGCTCATCNGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAAAGATATACCG
+
3)14E!"->=H0'@BG1A>8+&>*@;2=>2FE#$2/!D027!H84)-D345F4;2?2H=&7#%BA"BD,H02-8-
@r9454
TTTNAAGTTTTTNGTNCAGNTANAGCGTCCTCACATTTCTTA
+
#(("(*"&%*"%"%'!(*%'""%+%($'&("*+!""!*&&*)
@r9455
GCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTNCGAACTTAGCTTTGATT
+
95)H/-C!#+4-6E%!.>7F)-9E4;"4%E>G4@5B%!E5<=<&.&"(#-7>2
@r9456
ACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCG
+
%=B5/D1-)H6!1.=DA3.'<"(EB>*%D1B=E")!+:>6BB1+1->A3F2?33A+,&2G+,B==(89E4*"?8!6%F
@r9457
CGCACGCCCGGCGATGTGCGCCAGCGGAGTCGNGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGNGAGCCGGA
+
%:9.(>H,D/64*7<1'9"AH.*A2-0@7<&G8?<&=!&-$*A$=5CH4,!9@&;5+;2)>3(;FE&F)':@?C5=0-=AEAB48.4$+A&*0D6$62+F*14
@r9458
AATTACAANNAGGTTACTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTG
+
*)))%'")!!*)"%$'!++$**))!!(#*)!'!$')(#+*)("+(*')*$&+"#&'*'$$&!!%!)*
@r9459
CAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGC
+
@87C=8F.06G,'C"$GA%$"@!<CC@"H7-@$?@)>@C(>?7+&&>?#0=),9
@r9460
ATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCAT
+
>GD1>BE'H',41*?*"),#&07-(H%B84>'$#?>&3+6+5<"&>!G@.H;D#%C9)",;9+01'5#.)B'-97/'(2-9=AE/AF3'<&;2+62
@r9461
CCGGCACAGTATCAAGGTATTTTATNCGCGCACGAAAAGCATCAGGTCTNTCC
+
+!"%!"')%)%)*+"!*#)+'%"#&(#(*'#%'(*#)$+##"'()+##)(+!'
@r9462
CCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGATAAGGATTAATTATCAGGAGTAATTATGCGGAACAGNANCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTTGTGT
+
E/)<>:!GA@C92@C;C8$A&$2>;@3<G7)@B'3+09@<>69&C>H!>?F$2%'':*D*:0G.G>',1:11@"ED/',:D7>)?&$>;(8EC%9(+3"@3/AF:61,>#C>4?1G!>;G.H+A%D5&3(E+3<?<.)#$CB9>2B4%:5B'&D/#7;:84=#4-GCC2F/G#*E8"$7%F.C;F50D"#8#>G&H$%.2DC;.B=!&B5*($$,F0:4"9"F)5-B%!,/G24!,@!+,D1.
@r9463
ACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGT
+
C6:;>+F&+E5GD%4;>29-&D664E9:.!F<.&B:%=0&:B&;#'9E!6;6=9%#E!H@.+@:7!!C=+7G+H*E!C=3=>4+E!EHB/:G+D+)/)=@%C%G5H:?"+H#+32?7B#"=3""=2B'7B*
@r9464
TCTGTGCCATGACGGAGGATGATGCCCNGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAG
+
-)G&A=&%!6.=*(D'BF+";'$/<!?"0+:>%<@AE@@H7$B,(89DB646DF6*#@%!:2@<"*(#
@r9465
TGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATNGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCC
+
C4*F8?:E&"3BBD=A?C3'3/DGC,,F'DG9"EE<286/FG%DA(3E%(H;1DF->7H)E<?59-H'*A(H)8&),862.E(F2-F:<4:B63D2-G:-.D,,C#'#6'*DD''<'B1$.%%,GD3.8)"+:059#2@396A5!#(C/'?-!1@'B#&389*#F(G7$19/%3!F?*/H@:5A2,!*H3$1./C.=F,+#(HG14:("?*;"</3D=%F:
@r9466
TATTGGTTANGTCTGCATGTGCTATCTGCGCCCATATCATCCAGT
+
"00D-/38C,:8+1CC/A$33<2,8A6B@3E@6"E,*E3$&G4!:
@r9467
GAGTGCGAGGATTGTTANGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTNCACCGTACTCGTGATAATAATTNTNCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCAT
+
5"G=%%'D(?B.>G)*E/DC%'40)5!F-E%$E77!B"<@/6-0%60"&0H*5@BD/G3F""(8)D#5/F*&H/!42%$B2H<FE>*:;D2H<#?%8B0&D8-"G/,G.4+73=E.48"($1!#<&7E;><6F(0!1%?=;D"@2!:E")G&88'-*#;'6@?<*@.(
@r9468
GGGGAATAATTAAAANGATGCACACAGAGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGCCGTTATGAT
+
"&+$'#(&#+!($%!+!'$'!!+$%%#$(+!##)"'#(%&#)(*%**#!**+#""("'')$+''&'"('"&&"&*$'#"&+'*%%%)+&(')!")$*%)
@r9469
AAAGGNAACCATCACCCATCATTTCTTCNTTTCTGGAATTGGGCAGACGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGCAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATT
+
&#)%)!++*)#!%+#%!((!"%("*%"#&!$!")%(!%"$'"(&#"%(()'"''&%$"&&*'&"$%("')+!&!&+"+"$()(%'")')#!&#!&)%*"+'%")#*&)&#*"%'$!+$(#'*")""!$%&+#$"*!+%!"*#&!$%(#+*+&&"+%*
@r9470
TCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTGTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGNATTGATTCAAATTCAAGCGAAA
+
DF02!=%G?;>98)59&-#+&;/=-",G6<*5DFEE<C#@28/'&.%D+;3!&*#F122!A1H2!E9F,7?>&%34*"#;;0-5*;C7E3>;&:1/<$*><B/)"E@1#6GG!928/?H<+B?38.':-B"
@r9471
CACTCCAGAGCCAGTCTCGCTTCGTCTNACCACTTAACGC
+
BC6DG5==H8&G@1#2>C$&:7#9GC5,C-C4@*(117C#
@r9472
TTTCACTTGATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACC
+
$+0)=$(H3'CCG4;2H/0BF;/%%7(@E23?!<')?D>=8,4&-%-C
@r9473
GCTCTGATATCCAAATGAANCCATAGGCATTTGTTATTTTGNCTCTGTCAGCTGCATAACGCCAAAAAATATATTTAT
+
:*D1#./F#)<)!+:06>/3>>"6G'6/)<F4284<9H+4=3<*<#5!384#:9#%D).<*B&BF!,F<8>AD2E7%F
@r9474
NGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATC
+
!:=,"/#HC+'=$?24<DB$8,9&B*!&+9,76&?E68$'"0<G=?@"'D-+9.?);G,?$;*
@r9475
NTGCTCAATGNATACGTAGACGAGGGCAAGGCGGCGTCAGCCAAGTCAATCAGATNAACACTGAGCGATGC
+
!?#2A,'@?!H:<>$3&/!B%-D/!@@$C@A48?#A*6:>/D212<*49C&=62-0+48"2#03$!DAD9!
@r9476
NATACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCT
+
)?<:*:%(E90-9/%=/://;8?;@+;#<#A5+B1E)617
@r9477
GANNNGNCGATGNTNCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATNCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAANGANTAATCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAAC
+
"&!&'%!")#')$#)'++#&*&&''&)#"&$)%""#%$')$($%""#'"*+"!($"))%#"+#%((+)(&(#"#*##*!'''&))%*"(+'%")(&')$"#)'+*%%+(&)&+##'#!(%"#&+!"%'&'$*(#('%%(&'&%!'(#'#!))*)+%)$&'+&+*(')'+)"+*&+!(#+$(%"$+('&++$$&!&"*%!"#$(*!))%*)""*%$+$%')
@r9478
CTNNCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAG
+
&&"("+*((+%+!&'!%$)!&!*(&"+"#(*()&**""!((+++"!$$
@r9479
GCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGAC
+
3GEH)0'6B@0&5F6724/7,AA4%)B1!*F$5?FA%@#.1:9@A,9-AE1@/;>$@6DF%B1@$!-;F*70+#*:<HD/(A9C/0
@r9480
GAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGNTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCG
+
1G541##5-6;:4D$8,'CGH683E$?&'7(6$&<*&11:=8??3C5FD/9*/"-?G<?B+5AG,F?3FE0B8?<.02*
@r9481
NNCGGCGACAGCCGGAACTGCAGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGC
+
%$FD-B,:'=2A+:"388(:4079<*:,'C8F5G)05=8C#'/.-2BC?5F>@%+'*6
@r9482
GCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAG
+
+(!#!&'&!*(*#%("%'++"$*()#(+$$!!'(%&'&+*("'!&#(+
@r9483
GAAACGCCGTTCCCGGCAGCACAAATGCCACAGNTACCGGGCAACGAGTTGCTGATTTATGCGAAATGAAGTGGTCTGATATCGAAGANGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCAT
+
D7)?#-&1$;HD)4)H&B4%(3#*@8E!96..>22A(0#=HD;6>1=815CE37;C5;B*CD6A4*.2+C;2?E<+EG=26@2=BAF+3&-<,+=6CE='<#>B;@#;8F4>74E/*<"(20'A8*-)(FD0@F0-4$4D3#@-:*.?)5=#
@r9484
TGCCGANGGCTATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAA
+
=.:*)*0&163@G>2(A)&"(*9/<%=1.0%6&7,<;2G-&+(-(,*';$1<$)F<?A"4E;':.A?
@r9485
AGCTGTCATGCCGGTCTGCACTTCCAGATCTGCAATATATTTTTTCAGGTCAG
+
"#!G!+/#>7H=.+5A&C)F.0?==?HG-9"?2A='3D,G/#H@<2D*>=$(D
@r9486
GATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAG
+
(7;!$A+4!/$GF@@@,8."/(G=):*:?F"79393&7/34"24@A=">'B
@r9487
GGCTGATTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGT
+
*%!&)'!+#**!+)(!(+&)(+'$+&$%%)'('%''%*$$*"!#&*&%)'*(&!+(#!*)+&(*&"(*
@r9488
CCGACGGATTCCTGTCACCCTTTGAGGTGGGTTCCAACAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTT
+
H3F#(E9<!&E3>)511739'56F9'?97?;G@8D83B<42.=7E.G8#,.,F'+/9D?#@.0CDF3B<0!<<+:5%<*0
@r9489
AACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACT
+
>FB#F!,":&)6*<576DG30,-'9F)+02,?$3/@FD**,0G,D6#6B:)?805')F
@r9490
CTCCNTGTCCTCCATGCTGAGGCCAATACCCGCGACATNATGTTTGCCGTCTTTGGTCGACAGCCCAC
+
?-B92B31F-39+:";B8D-*6)?+B2&A4?AFG(--6*>H!6B@&DB#08--HG(.#0?#>7$'&<@
@r9491
GAAAACGGGATCACCACGTTGGAACAGGTTAACGCAGGAAAGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGA
+
<14E42:HB<F6E.*C8>@.0##<CB<0?9%:DF<.1!BE*;C*6=,%4B&7,<$!<@9%:2BB53:2;%!(3%4$5A:=3%58+"3=7G=DA#.G9?856#>462:F:@;91,HAB5G/-&?F$@$G*!$/'@4%CC"554B;.2#C.1*/G4;.D4
@r9492
GGGGGTAAGACATGAAGATGCNAGAAAAACATGACCTGTTGTCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAA
+
?6(%D/3!<G;>(67=:E?H3.>;>H0F*H)D:"+DC+09-,AB/1/BA*8.A4@F(*(/H9H?6'A=F@;/,%$52+7;4
@r9493
ATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAA
+
HBBB2"+0*%%%%C@+8*#AF&=%GDH-D=,()#3??.%2B2""&>6-$G'(A,;G#-8F1E@A%.$3E54;4
@r9494
GNCNCAGNTGNGAANGANNNCNATNANNNGNNNTANNNNNACCNNATAAGGNNTANGNNCCTNNNNGTNCNTNGGANTNANNNCCANNTNCACCANCCGCNATANCNAGTTNTNNANTNNNANGCAANNNGCTNGGANNNANNNCAANGNNANCNCNGNANCAGNNNNCGAGTCNNCCNNCNANTNNNNTN
+
#"##"!"##!#$#$""#$#$#"!!""##!!!!$"$"!"""##$!"$$"#$""#"$"#"#$##!#!$"#!!$""!""$!"$#!!$##!#""#$!"#!$"#$!$##$$!"$"!"$"!!"$!!"$!##$"#!$$$$###$"!""""$#$#"##$$$$"#"#!$$"##"###$#"$#!!##!$"##""#""!##"
@r9495
ATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGANTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGNGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCNATAGAAATTGAAATCGACCATGA
+
5;,-3:(:#<@6!985&H;?6D=EC17;7;8$,#<4#D;+<$!):D-*%!/<2:B3;:&C"9#(6$<%;.&9+(6#1/5)<:%AA)6<C2+0-8B%322A!*D@4.0;46<!/D7HA:(D+G90GB".+-3/C*$=57H#'6:?,+5,H;H2'1,,!1;<#4#E@/%CA2B9"6H<<HF&(8(4D$4F7;D1%7!,=E9C=#4>A"+<41&5<&4;'8,F.22+BC.'$
@r9496
TAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGNAAC
+
(A867<E7*EG2@12=@75+41F0"6#CH)04?'-!>:D=)"H1289';B);*F::$&</&(AHB.D!E3#($9AE=>=&><!)?0B/,<C.C646#;;@35,@18,:.CH,@'H3C?,&CE$:@;'1FD83?5C=
@r9497
GCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTC
+
<*=?)>=A909;+>843;!:@HA#$9+7#7'A*=)7(7)5,FHHBE:!E'G:9+H>;9?"D+CA!A-$C<34
@r9498
GAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATC
+
C@$0D;:644?-2%5B.*;5-"G9D)/.39)"!8>B25+?)>=
@r9499
GAGGAATCAANCAGAAGACACTNATAAATTTCATGAGCAAAATTAAAG
+
),%":7E/3%)&291<"A2").2>A)><%865%$@<*/,@48/+832"
@r9500
AAGACGGCAAACATCATGTCGCGGGTATCGGCCTCAGCATGGAGGACACGGAGGAAG
+
*,@=B/-&&5)!65E<6/+%>$CH2B=2,0:$,E3%;68.C=%#753#C2#9#199,
@r9501
GCTGTCCGGCGTCATCCTGCGCATCCGGATNTTAAACGGGCGCGGCGGCAGG
+
(/F<-1=E#H6!$*05+-9:"H::#D0>/2==,&.4F-6/"-*$-7?3#A(7
@r9502
ANGACNNAACGGNTGTTGGTGAACCGTGTTGATACATCAACTGCAC
+
&"%&$'!$"&()&%+*()")!!'(('!$%%%!&#+(%++&!(#!"&
@r9503
GGCGTTTCCATCCGTCACGTAATTTACGGGTGATTNGTTCAAGTAAAGATTCGGAAGGGCAGCCAGC
+
B+H.))H;3:/G7)&-GH@7:=22B(E@&&#.5+F>@-A:C5E'C%G7D!*.=':#%<"!?4.E>5G
@r9504
TTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGTCCTGTTGGCCGCCATTCTCGCGGCAGAGGA
+
AB4$G7GA20<$,AF!,B%F=%8DF$D684G"%E=<5!>FH%9/"F&#AD5')#3#C5$H>C:9)&(;/=5=+6-%>C?DED56<"/!
@r9505
ACTGGAGGANTTTTCGAAAGNGTGGAAGGATGCCAGTGATAAGTGGAANGCCATATGGGCTGTCGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACT
+
1-9(+E(936/HABB")0%#3)66=;#09;%7C-.$(E;1128@=:*%&!/,8A+E<CF,:'A*7!G,'3(*,2/#(H;E,0GB69>65%0+%!=$EA:D2B((@+%G84-F/G@$/&'9=2<'7E*<*?53C
@r9506
AGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCAT
+
,H+;GD-61&""5C=!#=B12G-8>/D($7%$9-9&13(GA"*=<6B>G@<C@/.#'
@r9507
CAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATNCGTCAGCGTGATGTTGCT
+
*+$++)('*$$)($))(!)"%)#%+()+(!#(#%"+$")!'()!&$)%#$)()&))(+%+&'"')+#)*(*(#
@r9508
AGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCG
+
D0G%0,!2FG")G5%871?4*;HD"$17A8&,A8'09B+(9:C
@r9509
CNANTGATGNATTGGTCNGAAAATTCNCGCNATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGC
+
($%!&$(%(!&%$$%'%&"+!&$"#)!&#'&)##%%!)''$$)!"!%)"*&)%(*"&'(%"##&"&#'(&(%%*$(+%*#
@r9510
ATGNATGGNGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGT
+
'((%%!(&"+)()&+)+)($!!!!)%$+'"!%$!&')*$')#(+%"+$+$%!#+*"#*)%
@r9511
TCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTC
+
&27A&+D90<CE/FA0#@C2%173,!(<=@1@4,@?)6-G(C3A)<-9.%:
@r9512
TTTTTCTTTTATTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCT
+
F-%!(<?@62-?'BC'1@./)G$BF,B:F,$8GH1F5F-)%".>48<55$"C*/4!>FE4-,#0F$GA4.;>0C24@)F6)+&872&'5,40G+
@r9513
ANCCATATGGATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCANAGTCTGACCAGAAATTA
+
!!')&)*%'"%$*)*#$+"+)!!""&()%&+$&*)''"'&)))#+&#$&'&')"!"$)*%$$#)%###&+#&)$)''!%!&+**($#$%*"$%'#(#"&*%'(%*"!&#)*#%$)#!#*+!&+!%
@r9514
GTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCG
+
.9-.2!G-%7*4BB;+8HAG'7)7FG".<89H7$H4,'1);&3./$09!BE1>*/)>;.;;"*5
@r9515
CGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCAC
+
,98#'9ED+:"9E3B*!A%'G/B#4&5GD)>HA&3$3FH@E--/H+&:CB?;,(F
@r9516
ACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTNGGCT
+
>,H==)/0@'1F@4;"8/($95;<+=>D!%10GG3;!00=B&B3A;-:
@r9517
AATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCA
+
1H<&F/D;D8,4%)&:/B%G*!@@*AGBH0>:="38>1%#@;+7!C#8A-G%G-A'HG?B)6(>%.!A
@r9518
CANNNAAATTGCGGTTATTTTAATAAAATTAAGCGTTACTATAAGTTGG
+
'$#%))+)#*$'!!%*(!!%()()*!%(%++'"$&(#"!)$(%#+)"*$
@r9519
TNNCGGGNGNCANNNTNCGANAGCGGCGTCTGCAGCCGTNCGTGAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGC
+
((#$$(%!*!!&!#*($*#&!+)*#+$)#("((!&"')&)*!#+(*)#"*+*%'&$*"*#)&#))&*'")+%)$$)"+++$%#)'%'#*$!&%&*"%#"
@r9520
ATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCC
+
<=H?D1A,G-F3:E%*F:+2'04'/;",>0F7<D1C5+!$8+";A77*8DD#;B/EC7@*"H5BH
@r9521
AAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCG
+
G-B?9=18B,;7+)#D"E3,+@"E51A"%2<@?/BC7%@$;ACH<:"9,CD3%A83
@r9522
ATTCACCAGTAGTACTGCANGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATANATATTATCCGTCCGGTTATTGAGNCATTCGGTGAGAACTTAG
+
,36)=%3<,74A).$96-;GC>H"C/.-B+&)9.$)'G*'1H:G/C-H'<./D2.BD&%=))*+2((:/*4F,H.F?8!$"55"3#42"CF*F8:/-D96CC)26A9#%"28A#
@r9523
CGCTTTGATATACGCNGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAAT
+
$*7<('=(>&GC89'3A.E>/4H0<!.*>+6(@(1C1>8,#GC8B<);:!F0*5H+19'A
@r9524
CNTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCCTGGCAGCTGGATCTCAGTGCGCTNCTGGCGAGCCTGNAGGAAGAGGATGGT
+
$&+(#))'+'*"#&!*#%+')($+'%('(*)+&($#!'"'#+%*+))%()$%'*($('$+++(%##($&$!&#""$#'!$#(!&+"&$##)%$)$
@r9525
CCTNGGANTGAACAATGGAAGTCAACAAAAAGCANCTGGCTGACATTTTCGGTGC
+
('("&%&'+"!(%'&*'!#%'!!&(*++'"!((')%+&)$&$+&+)"'()'($'(
@r9526
GGTCGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACAT
+
(=G;%%>3>>:.G=0!=E@8A(."6%H7.1)8)D+=,1F6"EA$%(?C(.C:4G&(A)G2"H-,7.AD"93H3?8*"$=E$0FF7"HF8(1$2C9,$B##HD)>)C<>,?&*#F/++68H%F"<4'85!:3"=5C2)C3$2;59CD.2C#FC0B)5$ED2H!)#90G2&<;65&*AA4-9#6E<<7!B!G33!H92$DA>=:.D?'C.HG4GE@7F$FC,0-'D)9<E%>91=8G7H<@1E,A(4*,&8.31-H?6,;;$+*5'H%372%!;F(D;%3E@G"$8E>-F*;99*9F'<D<>,))>%F4.1A*F0)'*5H%%,(A:7
@r9527
CANTANGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGG
+
&))*'"+'%#%%!&+**(#'#%*"'#(%)$#"+"&+*#$!#)&#$''))(%)'!%")!#!%)
@r9528
CGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTNACGTATGNAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCNCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTG
+
A.!C!73-1>;1$@660!-!17B,:%/##+.%/9B,3>,0A?FG$F@?4)@.@C?B$D95A+D5(GB>&9)=&7::;?>9'H+D,7)2@6-@67)$-$+"F"7/$@,G;8/EC2&,?8:9:(-F=436H/>$.=E'D?!'D9)='2B>2=3/;&&C-F&69C'40%;#0=13E82%)1H/#23&+D!-()?H<HF(A0@'#F
@r9529
ACATGGCGCTGTACGTATCGCCGATTGTTTCCGGTGAGGTNATCCTTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCANGAAG
+
27#'*%:8;H'8D1F;CH5C%$*G9DA185902%0D:(5-+2F#.27,#/F)"E9*3B38G'&>G*4B)!BB2C#F%-?DH@21G3F.&<'65#:'B$BE!<,50
@r9530
AAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGTTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGA
+
%+#%)"*#)#+#!)$!&"&!)"%*'%*#*(%+&#(%)*!!*"%+!')%(+)$!%!'))&!!$"))!$%#*+&!#(&)&!$#+#'%'
@r9531
TATCGCAGTCCGATTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGNNGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACGACAATATA
+
G(.('->)#4-=D=0(9"/0-+<=$?9!B3GEHGF8'"0?/CCEEE3;HG.)HB/E2)/E%G":F-(A$",@31"&2+FB!><)2?DF5!1&C8,,59:C19CH?A3&A&/549"64.?G8-*(A*>,.%..)!7)*"'"G@8!8.<')-A%6F@E&H)0FD2C9?H1-E0!)>0!E!#*9G1HFF,=1C>#.,":0,@5(G,@C""4%(4"6C"#%'+$%/4#?05A=E,><8D:727**7<'%?(F4G%;>:)E?8F4!H:?7
@r9532
CCTTCGTTGCAATTTCCAGATCTGNAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATNTTCCCCTCCCGGCGATAANCAGGTAAAATTTTCCGGTAAC
+
2?46D""7F?52&'1)<D@6$'8*&F3DH$C>E%&2-%9:.AB62,G$684?+A39D45+C8-0/A@84#C::HC5,%G6+/,H24*EHC3&!7<28H>!"D"H,8:$&<2=2DE)C>,&B+G-?9(61(7476H3B2>7>FE4HH@:F1>55<,=?,''+A%6*-;8#DH6".>15C!&-(C4H909;:#-7C7>=E7C
@r9533
GCAGCAACTTGTCGCGCCAATCGAGCCATGTNGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACG
+
0((</3#E3"011&4).2<D++=$,!$27(CDH40=F&B6E4:+)*C&88*)-:>F,"??)8=369./'@%..,6<(FB/3)'98AEF(<G+9=9C;>.5H,">4>0%3948B1>0;AFB;+12C8
@r9534
CNTACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGT
+
*/:5>A,>60==01%C,(6,G9#*1G/*,@;(%4:</0D$@D3;:0
@r9535
NAACAGAGGAGGAGAAGNGTGACAGCAGAGCTGCGTAATCTCCCGCATANTGCCAGCATGGCCTTTGAGCCGCTGATGC
+
'0(C"<B&?=9"#'%@#A9)3*/3/$&@;9,0B8(,$(5F/&%3<*CB?*?#-(D#)DH,>/1,-&*?=09/8B57-#A
@r9536
NTTCCTTCGANACCATCCCTTGGAGGCCATCCTTCCTGNCCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTGGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAG
+
!)*+G#&'$3/A0B9#;B0%<%-6C::C)"1F@8<.@)2F55&"1.C@)1E67@?8D%F5+'/03$2A;C(';<"$"$"450>=EFD6"H8*9B$9/>23#8)9=7A7F#$.H;)7A3E&5:$'<B0:?@4(1.%8#92"7$??"7A5894;.F
@r9537
CCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAAATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTG
+
4(;*$.>C6D&G)2);3H4G+$=8/151F2?FG#-6"@C,-9>D>11=#@E3$2:H,0H$%C9F@5&8D0"%&G)G/4:/6FDF3)6%B0+#.'E"9=!)C<H5-AC9;7>%1-:8#'E5AF82@6:5GA@B:07270.>76'?2H&+:5H71.&BAH,<+#98/;<E*!B%F*&ADGF<"@(;,**,&*:!FB5*=#5<4,$;4>#%:+F*8:F/0/)52$!"#0-4@HG+751'4D=5=B)A031=3+<@.50*-3<"HE77F@5F="565=A))!.>*+F%7H(+5;;#D$@4;1+$-H:G=F@C&7G$>D6F50>/"<11!F363>06G-0:@CH=B/+?=GD.'63*.'#,2!D&#,&9@;&"%,&77:D&8,*7(E""&<+779GF3<:9;<:';>=C
@r9538
CATCAGNNCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGNCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGNGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTNGGNTTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCNGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCGTCATNCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCNAATATTTCGCATGACTCAGAACAANAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTT
+
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
@r9539
ACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGNAATTCAGAGCGGCNGCAAGTGGGGGACAGCAGANGACCTGA
+
E@+?<B"+HF?A<3".1>A$;6C6C/8D!9/5=DE'A,+:$+DG'50%)H+:92G&>-D=GE(<="=F)$76>G):6%8HG!('
@r9540
NACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGNTCAGTCCCCCC
+
&(8>!%:'@/69FDD0'A'GC+4&925(<FF!6+/'(1GC#3$(<!$:9FEC,6!A%F07&'B-:
@r9541
NNACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCC
+
#"+"")%''!&*$'**$+%$&)$)%&!+&($#"&*!!++$!$)#!!""*!"()#"*#*%&*#"!&'*%)!)(%&)($*&"+)"+$'
@r9542
GCNGANAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTC
+
%'#$)(%+'$(!'###$#%&&"$(&%$&*(+&'()('$&$"%+"&$*"$$!")&!(#'*$&&*)&%!*)+(")))'"('$+*
@r9543
ACGGGTAANGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCA
+
)+!&$#)!!)&+("!))!*+('**%!$!$*((&+#)!&"+*+'$*#
@r9544
AGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGNGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTT
+
6:HFFFH<C=&62=!'=59$D;!'E&176%GC:&$0H4%C+=(B-2<H@-#;&3(CH8+00D@/-01F7*29B@7/-2A65#.;>):$?493/3">42!8:#/H!9!,;$C51<&
@r9545
ATCCGTCTACGATATCAGACCACTTCATTTCGCATAAATCACCANCTCGTTGCCCGGTAACTGTGG
+
068+D.78D>;9??3E-8(1>C?9#;0#D68AE#D7=71D#%5:H'/-+*->5A0&$/-*H9,G'7
@r9546
NGCTTATCAAACGCTTCGCTGAAAAAGACGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGNGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTNGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAA
+
";6*88'.348%,56?"77<#9H*7%"=1-%1*BB;E4D#4?'/6+9.)=+4<?=6HD4B@'%142&BG8A4-&B)C6-46H2C.>526.(!9<2?#1F.%3:$.9@84#B1+5FF?*0:&F=.-2EA&@";<3.'D&4A+;"'.G8,7#"-@;"11C="?<4>70$B@G:.4/C8$-:/'-)?:),%)@#>C2(-#7B>98878$
@r9547
TTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTNGAAATG
+
6"H-&?>110*8@3:F3B&H>'=<2D*#-82<1G'/B12+6D<F=8@G*9@4
@r9548
CTTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTA
+
$(2G?'-'2&D'6*(:0-89./&*)+08%%0$C-H7E6/H6,-=C/EC?".&?$A52?HB:7315D2FF)&=)05:D3.AB)7?;#D4"F@>#54AFE!0G;>"?2EA2"*/>>8GH7/
@r9549
GGCGTATCCATCGGCTGATATGCGAGGCTGGACGATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGTAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTGGGGGA
+
!=.+H3&@G/,.HGH%C$,3<&-0/$868#/4)$92-!?E#(.)),B)'3*7A2"4F;,:A6:#=0;F<B@0&E8)7B/0.&0;2=EE,=E9'4=+8.:0G%0)!EG"BC;A#.76+28;60<5<!3%@6)3#(@?D
@r9550
GAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGANGAGGGACTGGATTCCAAAGNTCTCAATGCTGCTTGCAGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCG
+
@D+;F1%$(%!=D2HA!B')FF#<3.&23!6#><1%0D$1G!D?29C01B1#)6"#4)@E='%<,%"&A@%4E)A/5A,"!'8+=!3-5!,3A7#E+(H+*>).F!/465;3,477H#H?/*%;FE@/0!#3CEAG*;=<%2)3.""%1/HB>CD?F..';;'%7$C&<0>+
@r9551
GTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTG
+
H-&?CC:565E,*'28$6#(8G?#+1-A6>H'2)<D@(&"6)<'(C"/3A-C
@r9552
CGGATNCANGCGCAGTCCTGTCTGCCCAGGTCTNCAGNGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCTTNTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGANCGCTGCAACTGAGCAACATACGCAANCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCNGTCTGC
+
#($%%!'#+##*!""!%)!$#+!'$*%*+&(%&*'''')++&#'*#)'%$$(")%'$*!%$(+(&"%")%#)($!*!++%)$&!((+%(+#%%+'"&)##"'!'+!#'!"*')&+#'#'+$(!!&**%"##)&+++)+$)))+!(**#'*!&!!#$!)""+!+!#*+$(*#)$)#'$#%"!&'(%+!+%"*)""*%&+&"'(+$((
@r9553
NTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACC
+
&*)*(#!+&!($$!$)%++$)+***%#))%"((*')'!#$(%++('!)$'%+&#&'$('%+!%#"%&$%"+$'''$(#)$#!()()&
@r9554
TCCAACCCCGNAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGNAGTGNTTGATAACAGGAGTNTTCCCAGGATGGCGAAC
+
#6,8%!7+,DF/H%1(E=C7771?C>#AA9'E63,%6AE:/'*>D<'9@2B6+;>/6/92+>D?3'<$$+*A=$H@>#EC=-7-$$$+'HH-E62D!27C325D:7;H3@926:),/D<(.3$%?)!?'"3F
@r9555
ATAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGNATTTGT
+
!1@3B?./-C'->"5-D7/:B'<$G;D0<'#95=775B3<@(!4;!G>(-9,94>3$%=3)H06HA8)%-&&4-=2"$**C52$
@r9556
NGCNCCAGCACCTGATATTCCCCGCTGACTGCAGTGACGGGCNGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCT
+
'&'$+*+*$+&#*(#(+")"**%+'"%)*"''+&))"+(++*$(*'"%!%""&"&($!&("('"%+*++#!%'!#()*%$'**#)%#$&##%
@r9557
ACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGNTTACATCAAAACAATTCCCATACATTAGT
+
9F;GE-&:9')2F6:='#'16H?F/+>9%10G%<2?7/*&0@+,46&?&H"A00F-(H3-C2<A5FA4>'%5**9/*C7,D>*81"E!B?2$F!D*!:?D(<+HG&0.5)F9"8?;B8?
@r9558
ATCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACA
+
%E?;8C-2!21912<G;.G)==E<0/&1:%3$$@C&;'26@H.#8
@r9559
ATNCCTCNCCNCTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAGGGCTTCACCGGTCATGGNGTA
+
"'!'%"$"#!!)(++'#%''*%$+(!)&+&+('!(''!"+!!&(&!*%(%"%")*(&!*++'$'%&%(+$+'$'#('+!#%&)*)$
@r9560
NCNNANNNNTNCTACACCNTTNNNCAGANNNTNNNCTCAACANCCAGNAGNANNTNANNNNNCTCNTTNANTGTGNNNNGNGNNATNNTNGNNNN
+
####!###!$!#$"$##"!"#!!!$$$"$$##!!#!$$!$##!$#"$!"$!"!$$##$$!#$$!!"""!!#"$"#$"$"!!!"!$$$!!!$##!"
@r9561
TNCNCNANGTTTGNGGNGNCNCAGCNNGANATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATCCTGTTCCGCATAATTTCTCCTGATAATNAATCCNTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTNTGATAGATAATGTTC
+
!&)!(&$"%!!%'(**"!#%##*"&)&#)"+&"($)%#(%*&%"#)(#')*%)$%&"*+'$%&&&))*&)%(&+#($')&))+'*!"&!*'(()&%%"(+("&**'(&"+##(#*&#%)$)&!!!)+)))%#*("+*'*()"+%()"+()&!)*%+&+#"'!"+$")")#"$+*)%$&$&'(####()'&)'*&$#%$#&'(!%!(($&!%*!((*%!*"'%!!")#'$*$"#$)!##!&#%#)!)"('%"##+*''%+!)#))*('
@r9562
GAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGGGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGNGTTATCGTTTNCTAACACGATGTG
+
07'HA!8H"%."?B%?$?):8:A4,B8F!759'B"0>H2EC(",:.=,CF1G+@+3,"';)+D@24H680B=7*-#E:<C8@6?@&F1#B"%<(8;?D&(#0<.=-B;@#6F!'.#0$F7%95$93!"B/96F,0;+$&B%,@,/E"'GFE&*'&7!8#31>"3-C90744
@r9563
NTCTTTCCGGAGCGNGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTTATGA
+
"-*:47=3*1<+@7',#-=7D):A-$HH8096+E:?&F74!4<23$.)/3A>=1H
@r9564
CTNCCTTCNTCACCAACTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCA
+
&%!)#'($!*((!%&&"%+*+*&#$&*("+%'($'&&("(*"#!%!#+')#$*"""+)'"$
@r9565
NTGNGNTGGCGNNNTNGGTNAAANNNTTNNACNCNNGTNTNNTNANGCCAGCCNANANNNNNCNNGANNTANNNAAACCTNNNTGNTTNTNTGTTNCCNAGCNGTN
+
"!""#!#!#$#$"!"$"#$!""$!"$$$"!!!!#!""$#!!$$"$!"$"$#"#$$#$#$"#!!""$$"!"$#!!$#!""!!$"!#!!#!"!###!!$!$$#$!#$!
@r9566
ACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGG
+
8A;015'G'$)!8-'5=9B3$/:AC;G:$;95<7:13-"12+2.H?/@'-5
@r9567
CGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTNTTTACCCGCAAGCGCGTT
+
)8?3=!:C8EE(562&,0'%)$>5"?CE)&3H09%'9".2"?(!@837?*'"C+'8//98A<;,01-F/F;:!7H%*EAB==;A/>#E/EF;C0,2D+0HE85$HEF8A9)E7-!6D$7<"-G,#0!21$9,C"EC4<"'4A97=3#-:10;;-.6H;--=;6(>A$D'&)466%H;@"A1)3;F@:!,%$!>E:;@-%/>(&.DD8
@r9568
CCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGNCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTNAACAGACAGAGGACGCCGGGCCCGCAGACAGCCTGTTTCTGCGGGAAA
+
-+-1#<D45G1>=*G+%FE8'2F0&,.171>1@D'(*(,BA0:-$:*'8*H!%+6/ED(<#0#&$<>82E%!H6'';*@<:D1/F&.8)$-%86&/4H.*$$+$0;F,":"E4G?.6*=;%*7#'HE=;-&,1"/7E*<+8A33H&#->2'6&E77:#@<33$GB4!)
@r9569
CNGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCNGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTT
+
*$+'$'!%*#&$*%("%&+("$*(+%'*$#*"#!%#$!#+'*$$+*+'*$&#*""&*"")#"!'*$$!%($+*&*$()'*)')$*#&"%$%+&'%%$*%*""'%"%*!%#$
@r9570
GTCGATTGCCTGACGGANATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAGTGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGANGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGA
+
F%&6;=.B,?G1E@9!2A%+4'=(@<A17B<?@@#!<=,0/$#8E+=0!$,B4=1-?19.<A.--#C</5>46%G=H7/62A;(FC,EG545C(D#='4<7"C$0E97:(39CD;#+!E6A<-%"?:G:G$"->:D+5)*(&=%9;#9H0>+'35E;1*<A"A.;'($;8',,!3A2!3%7DD)D=7C;.7-BH9>(2A24">C"A,8
@r9571
TGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGC
+
D71G<?*;F#4CE=!':D"0!+214!.<C7&E($*F@;50
@r9572
CGGACCGCGTTTGCCGGAACGGCAATNAGCATCGTTTAACTTTACCCTTCATCACTAAAGGC
+
0./B/-++B-7ED:?;6A@6*)*0)EC,1$#<*)979H?H.?4:F+("A$.!");'@B"9F@
@r9573
ACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTNTCACCGTGAGCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTCTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAA
+
.2CD6"35:(2"64C76E1+#G(0-9DC=?-<;*F2/$-/5"<40F9.@B.8=G%0#<F#6!E"?124<B-/?>3:,(=C1,4?-'38399F!HA9)?2-@;/%%&',5/+&DG*H3,'C;-*,?,))G%2)5&3&;8);E!'$C>91-D@#66A6<=B)<1?7;/*462D---G$1)24";G@6H60;@1HG=(<#4">E8D@)G=*B1G')<;&:2)2D
@r9574
TTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAA
+
36A92:?33H&%2<2$2C"4,.?;B.'E('++D9*"F93@!13E%21%CE%5()+E4,A,%FA!=E@)%GEB=>)%!:,&;1A;'"HA(2<#3#%*%=7E%"57/B<.4!+?G@-A;AD#21/'-:G%5G;0GF(G#9#D%65&C+AB!-;*3C82B58("(#D3@#&$F&A(!149!
@r9575
AGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAG
+
6A)'<<;&D!%/=>.7@=G+?8C<51>:)">'FC0;?E;'.,")
@r9576
NCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATA
+
$&2"*0'"!H'.D*DH?79)*C'0;C%9/,F3+>,+#4)D6G<?$9!@FA-E.)8(+*8
@r9577
TTATGTAGNTGTACACAACCGCCCAACTGCTGGCGGNAAATGAGCAGAAATTTAA
+
0HB.D($52,(97,,"=4$,"7'>96223<2+))"A?<'C/6,(<F!:8H//5?=
@r9578
TTTAAGTTACTCTNTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGCGGCATNGTATTGTAGTTTT
+
*02H3-"'>#<&*G*E46?,<E!>.*<@C1HD("27AC#"%F$H44E#C")*@11=43'@,G$$(7/:+&("5E$C*56C4
@r9579
TTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTNTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAAT
+
A6.G4C*7/0EGA%$8$<H0D-8?A8B8?,5!>G?'<%>)-E09#B4(?9F%04?;'?(?GC!A3H!%4%0(9B=-118;EH'4>$FHD,B37A)(,+&D"E#98,H#+!=3=A%=+B,*(A6,48C=:#<D:2=F!C$BD*F,A95$.0#3A/B(C";<C;H70<19F"-=C6'$25<@2?3;.1;@H?!2?.%&8(-%3F&+A/,).H1G5(B11'+;&;C%+A'</B)0B&-*(5H604H,9@56B*;<.>15>4=>-GC@/@'(0'87FA=7D7D@2D@GHH'/@@,5#">#97)2@*.3D)
@r9580
ANACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATC
+
D*-=&0H76';>?%,!'7A&-28&>=<?45"<=,-;>CF*<B>7'D:9;755@&)5
@r9581
CACCGCAAGGGATAAATATCTAACNCCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTNGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAC
+
F81.=&)E2"2(9:4&GH5="&80H6!*G,8=1<6=/B$$E:C-1E&7A24@C6/(F()(A(7G18/)B$@2A!<5-"<)&G?'1?@4?A<?(3DG;$;*47!,FD87+(F
@r9582
CTCATAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCANATTGGGGGATTGNTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAANGAAAAAAGAAAAGATTATNNGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGNGGTGAAACCGGATNCTGCAATTCANAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACC
+
F1&4#37#(016927($BD7>CG-',-)"1='+0&<=A>;6A><F>!+C;(5<DEG)4.A->-969;9"#<#&A+*17'=5C0.@G>0B,*9"+('@@65#26!/51-=E)AA4=F?=,-*#(++&A)@GE&H5E<#&923D,@!"58D@*3@"E$-=?B"!7&"A<AF(:/(#*1"F(.'/8H+%D+G8>;")?5D3';2B*)!'8.$75G)0FFH(D(3.F#CB!E2FF)91-7H&<%G.4;HB@,*A3'4
@r9583
CGTNCTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGANTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGNAAAACC
+
&'(+()"&!%+('"%+!!'"!#&!'&'"+#(!$"#$#'(!%!(%"%#%&*"'$(+%$"*+*)*##''"*($*)!!))&$$##(+&"!'$&#"""&(!+&)!&'"&$!++%&&&%)((&*#&)&%*%+*+#%$#&)*(+!)+++)$"!$$)+%+
@r9584
TTTAGNAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAAC
+
;,G(=2F6C:*?";E7>:*'A7),/$'+":C;>(9%'B'@!!&%(
@r9585
AGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGNAACGGCGGCAGAAAATTCTGCCAGG
+
),D95=?FCD#%=<@261(-+9&E13"-.>1G8*":6(35/E+186$:5%);9?=$4""$!3=!=*<2G<'C*C<D#<E>='
@r9586
TGTCATTTATGNNGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCTCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGA
+
;8=#?E6("+A!!(!C#C<4H'>5/$:9+$'&+/3@@(A00+@:,!15*9!A6.:@2=&-$F(87DE5)F4%<:A01=96@*:)5B5;3&H"1/=
@r9587
GCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCC
+
=D6:G7HD@&0(/*"7421?1HA%D,,9:+2%0.=&#!93<5-)1BF"-:6!'$>698>E(C"8G:?A6B3"B1?::#2H7HHG(%/)&#-/'.#+DB2521-9'&$*
@r9588
CGGAAATCAGNCAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTG
+
FD=&63*>%%+<A;=BD42B>$0:'%>?+-%*8.0<&322GH;H=0&4::B03&'&8:*C<)75,
@r9589
GCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCGTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGGACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACACAAAACAAGCGCNAGAAGACAAAAATC
+
0,>>G%>&,8.,5"'=E-?$6H+:(8;G9>,!9*3G=+#/B).6E&$75(88$@@,C'G-F;!9*'+F*.42)."(./9?8)-7:5?;G#'4;(///-%>GE:$@F?$(E/&#.15E8B#H.6<1@4/4CHG$9B$H=.G>H=E<A)-)7G*,;;D@@D@<*$'CA*1C,0&7,:H=*>,<-G$?@/:=HCC
@r9590
ACGCTGAAAAACAGGCNGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGAC
+
$+B$+*F-.1-6F%(%'/1(&?D$=CB9H7/B39$93!*@+@4="+&&3;,#&$G<2;"+11-G&*4*!C?>1-D55?86#;5=;$6H2=1E#:%?EG;2#EC8=$28C:5%.F#=+"%A
@r9591
GAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGG
+
0#??/&B-;E'<,'+7DEE"EDD4CDG%=?&$C53702:50B<;%4B/:67)"%833>
@r9592
TTTGGTCAATCACCTNGTTTTCCTCGCACGACGTCTTNGCCACCGGATATCCCACAGGTGAGCCGTGTAGTNGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTCGCAGTTTTCGCNGATGATGTCTGTGATACTTCGTCGCTGTCTCGCCACACGTCCTC
+
@***$.3>D*-'<*&$,8/&D3A9%&3<<D%F'-'5'%?#1$G@'$44G2?B>4633$?05>5A(3B-?;C77%5'?*#9.?B%30.2$!"-4-'=#$GA'3:C;040%<&#HA%;5></;9%H=$B+"#5D+<+F'!+E2406,$&%>..27!;.,,2"E5=9A<#@,6%!D,<-7*?=2#/#,#7.1+501&D,=*A;
@r9593
GTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTANTATCTTTTATGTTC
+
D2A0/AF&4*32.D<?+D9:!?1F44:*,F'12:=2>;&:&8@E5#>,"G6,"'FF//E%E3?!;D!,"6
@r9594
CCCNCCNNGNTCANCNCCCANGTGGTGCTGTTACGTCTGGCTTTCAGCTG
+
)#("&)"!$&%#$")"*("!#&++**'!!"%)'&!%)&"###*)*$#*#)
@r9595
TGTNGGACAGCATAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAG
+
+2@)?7.,8-*'CG33A>?;=%%45(A=*43)?>31=0(;CB.6!-B.F)",800%3?#,?:4!+>;"1%H0.
@r9596
GTTTACGNTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTNCAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCNCCATCACGCATCTGTGTCTGAATTTCNTCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTANTCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGAACGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCGGG
+
'&"#)')+#(*)&%#!+)#"#(+*)*++&!'*&!$'+($)')(&$*$#+(*$'++#&**%)%%%("#&*)!"#'$*%"*'$)("*&%!*'%+!(+'))*#&%''$!#'##"**))'%))(("$!'&+('("'++*&!#$($!(*!!%)&%!!$&"(%$#!*+"'(&'*&$)$#+)('#!*&!("$$+%$!!$+%)+("+()+)(!&'##&##)%%("''"$'$!"($'*'#"'"++!*)!"""$#*#&''+#"!&(*+#**'#!!!)"%"(*"&!*$"'&!#$+$"##"!)")&"((#'%)*)*')'$#!*'+)("*#"(&!**+%%!++"%*$!$%#*%%)$'+#)#+)%!((
@r9597
CTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTNCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGA
+
()&&'%+&!"$+#(%%!"&*&+"+!)!(')&'%"%%#(!*&")!+"&))#*!!%")++&$+($'*&'"##"+)+%)$#('#!+#"!+'"$(#&*(+##+'**"$&&)#'&(%(")
@r9598
ATNCNANNNTGTNNANTNGTNTTNCCNTNNANCTNNNANNGGNNGANTNNNGNNGN
+
!#!"#!"!""!!""$#"""$!$##"$"$!!"$"#!$#!"###!!$"!"$!"$"$"!
@r9599
CCAGCTGCCAGGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACG
+
HG:+&7;$=0H.&-2GD3"34?*?AGG)49,F*HFDG=H#GH17F3$'A?".,H0@F<2@':2811&1FFDC=AGB4-AF,)'@?"4+A!<)E06"""/7DB$EE>$$C*E>#;>7"/=8:)*D7540?G=-".&#>-+<>(%&9/,!9=5<%A-0?;C?B*"3"7/=AC=2C?<E&7C;4!=:3?*F$G*518>*;!
@r9600
AAGAGAAGCAATAAATATTATCCGTCCGGATANTGAGACATTCGGTGAGAACTTAGGTG
+
:@/DG+)+:""<)4B)G3G7((%4#94F<470>B3%.F7:"6DE<$EF*B3)(+#-,#E
@r9601
ANACCCGACGATATGATCCTGATGTAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTNTCACTCGGTGGGTTCCACGACCGCAACTG
+
*!,(&C=9)2C<CF$9@'<:+%1:&25"%53,$)!4#%2A5DEDE9?$F*!9%'+5,2D<>3?1A/:6CGF3@4+"-?1/5;CA,38A51-E:07"!EC*5"!,!/;>,98321G?15%9"8%>G86?::+-04!1/**5B2->"63-9,10$
@r9602
GAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATNACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGC
+
6A1=$3-D)5@13(@1/6;A%3#!49#'::.">E=?91$E(/+1:!+,43%2G%%3970C$&%;@70@*#5C=6)0=:059&D+3$+D0#',>>+<7EG@&#?#6C41%>6E76@AH%61E;=BH8:383C.6H%A28?),60A49;E3-06,'2F)-E5A1+->$7E-0?;#G7-F28F$?)+@>6E>!*/$;=0!,+-85*:61%%#1:H;7G;/9$/5=D"03)9+@9,%.==-(
@r9603
NTGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCNGNGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCC
+
"C?F?3A%9&%9?#B0")B1,&3*@(:A'>?/""8@$>054(7A7F?,?F;-7*+2%A$G78,$C6+@G#07;?8.36E8-2)@#0F)<)FHEH:)3!E!'/H'#7'D
@r9604
GCTGTAATTCTTCTATTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAAT
+
/)#-D&:18>;;:-H-,H,>)+AH+B4(!D!$;)>C!'7-6'/7&&&7'##/<H-*D5@;F!3%<&-5H@/,1
@r9605
NNNNNCTCAGCTGCTTCTGCTTTCGCCACCATCATTACCAGNTTTTGTGNAAGGGATGCGGCTAACGTATGAAATTCTTNGTCTGTTCCTACTNGTATTGGNACACACCTGATTCCAATTTGAGCAAGGCTATGTGCCA
+
#!!"&%+'&%%"'##"+#&("+&!"#!*+!"+!+%%&+$+*)+$"($#!$#"*#%**!"*!(+&'##(#"$"(((#(*'#'($"$+)'+&&*'($"")#"!))"(*+'%#"($(#*$"'(')%"++&!(()+!)"$$%%
@r9606
CATGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCGTTCACCGGCATTGTAGGATTTGGTACANGCATAGCGTCCTCACATTTCTTAGGTAATGACATAANTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGNCACCATA
+
<,%3'(C)3,G72;3.;""H%3;!&"/D3532#C*$;4<;B1-+,50,.>,$,4"$4C$H+5-,GD2#:<7*!<(6:'%/07$3BFF(C98',CE9D6F</F+=,"E(#6G2*06;,EB8$G:"%C&!DH&'>A14,#.B/#!#=A%4F4=9!;$,AGD@%@E3G-+&7>7#3D+(#FA((C$<1G<"0+9&>&AE&2,-5(D(:*G$1-)<H@A'08%51D/"C7D'%-)-=>'@
@r9607
TNNGAGNCCTNGNANCCGANNGGNNNNNGGCCANCNNNGCCNNNNNGNCCNCGANTTCTNGNANGCCNTAATNCCNTNGTNGAGCNA
+
"!!!$#!$"$"$!$!#"##!"##$#$!!""!!$##!!!"$#"!!!$$"!#$"#$$"$!!$"!"##"#!"$$$$"""!!$!"$#"$"#
@r9608
ACAAAGTTCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCGTACAGAAAGATNTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAGGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCA
+
@G?".-G5$%@8D"$'A83$E*H!,225DH.0/CC76)@'1.237?%@"D;=!$6G.1AF#C?@#%B?19*GB-(-,C1>/9)?<0=?*/+)<8;@)'8=*2B1>+(B7%#589DC:*/";8.,2EH"04!4DA:;:D0H:(4'4B#+A,(C887*;5%-"+:+!@!";B3'1;0<$%F"?<?FH/C+A/"%*'&3+=8"<AC#"$<C5$"/)"#&-F1%>$<A&=.:H@,>H?6%:@@#FC4"913,?A(;7?FHC.11G@3:?>A$A:#$=H4&@)EH9A2E-:A)C,/%@+!"A:B;'B8$AG=767.:&8+#%$7"@$@2)D@;/E.#:/A8:'@$1!@E<=1F(>?,DADB'$=EHE<6H:D6
@r9609
TCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACNGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGNAATATCAGAAGTGGAACGGCAC
+
($+#%!!)#%!"#%+)*)+##($(#"()#%%%$"($"'+%*")&+"'"!*("('+$$*!))$)%##"$%%%+&*"!#+$&')++)++&&(&+"&)%"&(*""%*(%$++))#&+"&!+!+##++#&%("!!'*(+*)($')$'$'$"")%%*"')**&##'*(&)""&&+&'#%!%!*&&*#'&$"
@r9610
ATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATANCAA
+
7(H#B72E?:!7$?,,3+6-$@="H2DD%F!0A2&:B#%EA1%>=A%>/!+H7+3(%08'D=1!?*GE)1%
@r9611
GACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCA
+
.:&-7@;>A&8/$&/-.%?!H88)1#*(9BHA=3=<2+@%2&+C057FE@9H9$B=
@r9612
CATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTA
+
-;-!C%4%3>D7$#H</@8.@,H))9@5,5>83>*#&)7#!3A=9
@r9613
CGCCAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCANCGTCTGAAAGCGGATTC
+
706?D'7@:C4%8(%;#0#?1-)0G),&G$;*/#11':5+%/'/*:)2E@B?#(:))*".45*+E":'3H/(44(C?D?,@C>."$=$43?E5;)BC,"'4A"#2$-;485)!4;(H>"#3&F;1?=2F11:<2*CG/@3>$B66)=;;8=>!*):$0:??@HD#,!AG5@@+4=D2#'8.?20.67,C,#*'#:&+);'?+H(HF%:.D(
@r9614
AAACCGATCTCACTCTCCTTTGATGCGAATGCCTGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTNACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGNGCAGTGCTTGATAACA
+
680$';AH-G*=E!1&8G>23+@'H,*!2FCA83,(/5F6/$9B73;!C??D.3*&B8=F7G*(/4(9>G,E;+-E%HAD,%(B<90!/6+1'&B$C-G0H<;&;37F4;C>C*1?41=@*:&!=6:H4(+A'/4?38?)(@0+$'1B0>*F(0F$G2G/899(H.?6(F6+&H/$:D4?H%1*?3E*!<':F
@r9615
TCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGNTT
+
@:6-F!:35%1C=-A#A;$-;.&()GD*F6@)(1)'4;!D1!$)8*)";C6*
@r9616
GGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGG
+
G+A$46.++!%>'+/.+>EB72@=**H2<@3G/1:"8>H9!44C+-G;,0$796-8DB9D=#G706))53*D-&?/64?85!,<!B;6E1#*01D,'6347,7:9B!58D$;0HA=4E,+FF?9G/E2'F>
@r9617
TCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTNTTCGATTCAAATTCTTCGTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCT
+
,#G2D)+860/G!A>E/07+>,,=B),%*H48@2$1#;4/:>??C7*D>@FG%4:2"+C<=H"-1--<D<#13E"5(F,@&*B@9!3-3D8*:A,EE0(78",4"0E$AC3E"64B('947(,474+=:2$=-5BA<9!2?G%*(1(
@r9618
NCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGA
+
)F3C7F-00=CC@F*;G(6#)5@F86DG@@!!*F47F+D.*(G"3-&2D=8F
@r9619
GAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATT
+
2G:+H0;%F!@'4@,#F?6;G#&5=A81.A@!;>C<#=<<H(A;E3&H2
@r9620
ANTACTATTTGCTGAGAGCATTCAGAACACTACCCAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCNTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCNCTAAACCCTGTGTGCGTCGTTTTAATTATTCCCGGACACCCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATNGCACCTGACATACATTNATAAATATTAACAATAT
+
"+7F::6B!?DF;!C>5E=D-3,H717E502&-D&8=D+23&1F=A8=D50=.*1F,G7:D-"9!>;2D2E37?.;?,$3F!>7CA.$:<'$@/9@3@,'F@%/:&?:7&7*68>/;:=AF;GG,'97!4%-FC!:>)22)$9E@"$B,GA7@8#F<%8+7%3=<E9'BHG<55$D6&>.@=A-3&)0/";!GC,8/(18C#>@E%D)<4A7C;7@0?&69,0.>C,$BA)A-.))%50@5F3C!5=7301A,E.39
@r9621
CAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCAC
+
2EA72-3@BD@4=30=#5C)*%$#1?:6%.=&5H:/&4G:AC(8!
@r9622
GAGGTCGCCGCCCGTCACTGCANACAGCGGGGAATATCAGGTGCTGGCGCGATGGGTC
+
E4@D%)&=41;98H2!*9!+G#0AF80&-)*F4#+%4B')H:1A"7/E?2>23>=<G7
@r9623
CCATTGCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCAC
+
%(8F'2)0$E?D3FG3'DC@8)8;2AAF$C187$6B0E&FB'<,C>45(,2@.H
@r9624
ACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGC
+
>H96B824/"CB;G1(>90B?2*GCG9?"G)'&*G0)6@"6A+&%'$3755#/&)>+D51<$$E!E@?(@',9&&A0-*EF6):1
@r9625
CAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACG
+
B2DD"F1!6!%4G*05.#@)DD9(E2DDG&%6)<>4>1>H;,3<?(;D*0E)/H%23"6(D/#)A$/2/B
@r9626
CCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAA
+
@AF7@E+082(1.4'<30$H;<!#'2.2">;D:,E1%G66(8>3#1E36?6F>CA@#$+8(8;%4C,7*7?;-F#G$#E;")6*@+'B-"F;@DB2*&
@r9627
CTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAANTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGNCGCGAGTNCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGC
+
+2G/*C*+!2G2%+<!)+2C/4$B>*40H/.1-;&DA"=(0<39<752175;8E7528A5,6@AD$$,>H4"2-/9H=3ED$G&(EE0D',>!%+0*<0.!4(<9:4E&0AH"F@B)'38&.?FD)*.&0A*4?;#,!);802%@-=0B;'10B?61H+.;:!:&-6?/HC52
@r9628
TGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGNCCACGCAGTTGNTGAGTGTGATCGATGCCATCAGCGAAGGGCNGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGGCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGT
+
<=.,%*2@/A9C"+#?;G:=.B!?57.(:5/?FH.H%#B.<-&#7*>?F)),.2!'9543G,H,$4F1@-F28F<(G,6,/94.*FD88,3E1G=F1'#+$*19!>%%"D9/G=(2B@@#=<0'D8%C/;;8?7,);"H'/:1G$!8(*<#H3?*-B055?G1%134@-HE=7F2(1,?=<%>H,AEG"GA8#6C&;%:/-B!F13<?CB*FC$,F=-064+'.F;23(9980:;7'#30."D1"./'$+C>@/4G39CD95HE5
@r9629
TTGTCGCCANATTTAAGATACTGCTCCTCGCCGCAATGCG
+
AG;&D0:;5:'#2A<>-%#(!8;8%A%(D3".AB;,A!)<
@r9630
CGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCC
+
'23/C$..7$0-G%#>5,!A*/@;&7G>(C+AB;8'FEBGB'/B7"A7B;C%-"
@r9631
TCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGANACAGTTCGCAGGTAATAGTTAGAGCNTGCATAACGGTTTCGGGATTTTTTATAT
+
=>0B82$F5,+58D:B27853.B07'@;E,.D:6H2;)&7H9G6F&9*$=.<&=/E3,(<G!A.?=8<%/ECCC"F+C#>#//$8#25$>%G.-$:?G:G6*F<<(";E
@r9632
CTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGT
+
+'")"))(#$&"&'&!$((')%$&*!'"(!+!&$)#!!*"#%+###&$*%'$)&&
@r9633
NTATTTCTAACATTTATCTNCATCATACCTTCCGAGCATTTATTNAGCATTTCGCTATAAGTCCTCGCTGGAAGAGGTAGTTTTTTCATCGTACTTTACCTTCATCTCTGTTGATTATCATCGCT
+
$++#'+"#&!*&&("!+("&)'$!(!#%(&*%%!)*"%!++*))'%%*)+(*+*%&!+#+!''$$"!%''%$*(++#)(("#%")'%)$%&!+$#'$%(&)"'+"+"($('&!$"%"##'&#)*)
@r9634
NCGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCNGNGGGCGAGTCGTCAGGAAGA
+
):32*/@;>6(0F&+2$DE/-!+3<G)-H38'"2H4:4?=!9FAGG+?2%>'A*,$C81<.?%7/.#B%+>&5(DD,;5-+&@>E,6.C?E><+<@
@r9635
TAGNCTGATTTGTCAAACGCCTGCCCATGCATCAGGACGTAGCCAGACGGAACGA
+
=C4<F9DB,8$?GA2#::$3?D(,2:E*8=36>(B3)H$4%-2>158<H28'.6?
@r9636
TGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGNNTGACCAA
+
18>?1>C3<G$%37/0%)#H9D"&2'.=H'7@10B5;5."65>>3?($+,2564%+60FF<=0(=
@r9637
GNNNNCNTNCTTNNAGNNNAGGNANNNNNANNATNGCNNANNANANNNTGANNCNCTTNTNNTNCTGNNNNNCTNNNNNTNNANNNAGCNANNGANNNNCNNNNNNCNNTNTNAGNGNNNGAGCGCGNNTGGGNNNTGTATGANNNTNNNNNACACTGNTNGCCNCTCGNTNNTGAANGNTTNCCNNNGCNNCTTAACTTCNAANCGANATNNNNTN
+
!!!$$$$#!!"#!"""##"""""#$"!$"!#$"!!""#!#!""$"##""$!#"!"#"$#$$""!$$$#!$"!$$"#$"!"""!!!""!!!"!"!$!""!!$$$#!#$$!$!!"##"#"!"#$##!$#"!#!$###!!#$#!#$!!!#!!!!"!"!#""$"#!!""#$$$$#!"$"$!"#"##""$!#!#$"##$$"#"#$##"!$!####$$"#"!!
@r9638
TTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTTTGTCCGTGTGAACCAATACTGAAAGAATGNGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAANTGTATGCGCATGTGCACCGGCACTCACGGCT
+
?$$+->$891@;6A/=0<55+G<.82&:+-3+0<,$"1/>-%2"A99;'?!76(#=-HC9)D$98%*:,+0G(-07':B.FD>B@<A,6.1)9C:$'5-A;"-D&9H/.F'B*(G*!&@6!"0G<52,953;$$>3?7#@07%EC>8//G25%)<BE3#"G:;;H.,E53C@?3#+;-*G/D#4)@-*BF2*-!E.";86/D!<=>'D=749#:84A$0!0"9>"@8
@r9639
GTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAG
+
G0C*H4FC;&")G$/=!%6@!4)E-G"&4"17$>H5565A>:C&E%,.,-C7D50<=%$D,/C**;
@r9640
TTTCGGAAGACGTTCACGCCGTATCCGNTCAATATTTTGTT
+
H<'4#?",0<C?&BB')#&(!*;$3,2?HB+*D;G@.82%>
@r9641
TACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTG
+
'87.#?.;@+%+?&C981F"$5>#884683H1.?3%4GC&D'70.3*.A:'
@r9642
CTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCNATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAANAACATTGTTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGNTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTNCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCNGAAACAATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGT
+
?9("=.97'-8B$=:C"A#4@B,#D"2=C,,F6;'B?"42+3H#@4,DF4'HB'<&$.+(#:GD;C7"??3EH>>5-23043>="'G!5*+5)=')%B.H(/?7,&D#/>+,>/H1&@:/(F9:@1$C5$;,"&6699;5<>DHG2E0"8$DFGD'5)CE'-.%D8'74(H/$"F6G+5/)=,:A0!@-,13B92$%9$47G*%%65:!+29,=$5*<,=552(@9<.>*($2+,D(>;=8AH!B!,E12(:2*!F>25!1B*0(D<C+G8%+'8)&/+41F14D'G@&F=&#C$-<+(:H$),D!1".:1%.3:F3C'(*37<:&*@/E0>6H3"+:4C5E#H298;607;6C>*:4=,$@>E:0B:GF*%"@/G+'=#&5!4$+??6#/<-<=37;H+8#+C!D4F6E.)1(EFGD#C&%B<,F+;'H-)0859B?C0*.(D"387@@</A'92@B2HA,61%=BG%A@,5#4!.?=
@r9643
AACCGCNGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGCCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCNCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGG
+
;@;!4-6,/4C6:%@!#6CAC$.(C6E.%*,:%,7B6E(D5/#G%D&H@1-)D$/,)**4+!+:=>1A82D>-HF5/G27"DE-G=(G.6!9837(4EDCB5)!#AB%2,4H!23(B,GH8">E=?#)8F)!:98@2542,.63*C#'#2)$$#!0
@r9644
TATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAANAATGCGGATATCA
+
<)4.%-H*::5/?.C<;*%;.<;)898"@1#'&@H<:C*;3+BHF@?C9:>?E#-HF<.C@A4">8-CB9#</'CF?:2A@:G36:<-88?0%C5*,&$&)4<>>GC!;"D+H<99F'"D
@r9645
TCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGNTAAACAGAACAACAAAGCTGCCTGAN
+
;""2FF-%D+@43966*-"CD5"D6/03A;!6"B9-B?A:0<FGF3.',38@@8)'$G.>53(H@5;H:"BE8*)
@r9646
NANNAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTNCTATCTTTCATCATATTCTAGATCCCTCTG
+
("%&*$&##++!#'#&)#)*+$#%##*$#"*+$"+(&+($+)(!$"(#(+((+!%&!&+#'')(")%%&$&)%(#!)#&"'"(##'&
@r9647
ATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCGTT
+
+*+!)*#+!+$*#*&%%#('+!#)'+!*"+%+)$'#!'%%&+()'%(($"+*"(('
@r9648
ACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTNGCTGCGGTTGCAGAAATTACCGTCA
+
0:B*%H:+70AD?D@E+4C!8"&84>.+4%&">0CBFC.4E*2002C(9>'2,"5&??6A5AB5F+:!H2+?3H3!;4+88D<0+D:.(0<8B78?$:&'%+#%=)-4@$#+B*%*.%$&FG8@
@r9649
AGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATC
+
:9*2(;?E(6<8#G"+(B>)E):/4:'/GG88<:&:'.53H1,A.E$24H<05D"E&))5+,(=$(F>G<?3-&$
@r9650
TTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCC
+
6;D>/23<,E#C@/4,1!72/7E/'-A!.4'>84H5C57B07(<;B<FG-A*@@ED0F)!*(,5
@r9651
GAATCGCTATGCATCGATCATTTGCAACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAG
+
+&)'%%"''($*''$(+"*"''(%'(!((!(#"#'&#+*(!%'$+%*("$"!+(*!#%"!$''&$$($#'%%#$&$#))%*$!*))##&%*))$
@r9652
AATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAA
+
10<<'-7DBC"9!6G=83(%1F:&8-65=9(F6?$,@@+2/(,/30:*H)+%<E31$@2%4'AA,?"%9@GB//(8>
@r9653
CTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTG
+
C%>52/G?1'4"8(0!@G63,/%6+<;D$%-1)8&"9H0@
@r9654
CGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGAGACCGGCATAGTCA
+
-%/=$0!D+7(A%@??7575.$@AF$;)HAB=AC'/?!$>=8,HE,7'0"(*-:<1'6,C6A-;BF@9,)+
@r9655
NTTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACC
+
!&1F4%,<#:BCE(@C.#4>%75%HA.?3>7?78CF*G/@!&,,404!)-"F&=%/B-G7,(.(7*@9:D#"$127-"D!@57!28.3&?H.*"7#@3'!:H%:3
@r9656
GTCTCTGCCGGTGTGGCAGCCGAAANGACNGAGCGCGGCCTGGCCAGAATGCAATAACCGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTANAGGGGAACGTCAGCCACC
+
7+1:'";("8"7(#1*#9"1!(B2?%9;;9H33GDA76(<<EB?G>H33=+1!3CH0.F"D%B,438G<?B-B6-)?8?*0HE*/9B2$8/86EG+>/<?,A-!((-2(23),&,+4H)2(E)!+6D,D:H/(F?-5G=B3&(!F978=6=3
@r9657
CTTTCANTTCGTAANCAATGATGTATTTTTTAATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGC
+
%&#&#)%")%$'#$+"%((!$!%&!"#'%#''#'%%)'+""++#$+)'%$)'('(&"&'&&"$%!$""!("$+
@r9658
TAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAG
+
/GBBD<0.+D@4/>CE(:?"-#)GF;$/9'-%/7#4$FGE)%+,(-&2(+2#1->!>&5F><A%B%441=:$A&&$@5/;#/8.EF#).7;"C/:!4<-FF;C'1F4:&&1;?>-DC=#E536.+!9!$B@*91-+*/7>(,4=4.A:+9B%'"-$
@r9659
TCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACNGTGATCGCATNGG
+
/%.<30.'2A:5"0&E-C5F15:(=)2"H1*$G-"';?%#;.8(&B7GG3320A"8,C:5((*6'37.F"--?6:B)*&214+1$)-2E).@9&1"&>(1B6A9CAG4-6D25=9-%=4&4;>C0"=
@r9660
CTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCAGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGNCGGAGACTAACGTCAGAAAAGAGAGCATA
+
0<&!:-7C-2'1+23A66"!)7#0+#:E!&&D(B#?H.C@.+<(;E,$>3!%%2E=#D!6-E;H/91$C3(4#$)!(HA""-/8F@;%:A#42CFC4*E=:78E<+B/735<3@91;'D9
@r9661
GATACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGANATTGCTATAAGNAGAGCATGTTGCGCCAGCATGATT
+
E2;/A.=B>E:<.G6H*;:-@=-59(@55:)&267F$AAG$&;$F@28F9E<&+)A%G@A>$>4>%*(?)3::15%..A?D""((@,>:;%##*&H5@=BAAD4@$5=6E9?'+&!=(3B-6,2=#6
@r9662
ATGGCNCCCGACCCGGACGATATCGAAGCNTACGCGCTGAACGCCAGCGGTGTGGTGAATATCTTCGTGTTNGANCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGNCAAAGCGGTGTNCTATAAGGGGAGGTATGGCGAT
+
582,"E*FB,"">!E<3625%!=H->%D@>H&*!H46,<F/"+15E+07!;1,!4#9B)>AC2@&5***<+#$60---+/.'GH&H&!:2%7$6>=!0+';8>=;D042B/6.$F@*'>F0=DA%1(!=8.2,H'<D=6/#F114*5%(H6G3D"?C=G0)%E270001:D6!@2A#48,AD3(*!",4-%/-"7/:18'4(A:#:F@8%G!,
@r9663
CTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCG
+
-@&/C'-8*'GA?;'@/"2)5";6F(&*56F"D$;?E!'>/0B-.BFDC..1DF4A!+D8B/9B--BD<H.C
@r9664
GGACGTCCCACANTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGA
+
BBA#3BHFE!+'F3=DG:E:87;7$/02>(F@%H)47+)0G0&1!"?H6@'A#=G-F!-:(H+G@#F
@r9665
AGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGTAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGATCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGC
+
+=B8F22(&@GD&<:C&!@>=*/9$/>91)F7>H>+2B?7*5#.*B&;%?5+@'9$;11//826GH%4+!<H6@#5/9)H*:$4-5",)=75HF689'*:B&""5=D78GDG%<(76.)6AG+;5B?3H=/<9E.%!&$88FD/E%/GD.0..A'5>(%3<>9F2(5##A/>@4A'-A)<.BH?#E5*,#)?&7G6@7A)#5?D&*
@r9666
TAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCNGGGTTATTTATGCTGTTGT
+
,F:$G:)5H;#G1--3-8:3#3'3(7GAFA&##"2;;E?(2";D$&(,0,>"D29%4%$;1-%)C835<%?
@r9667
GTAANAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAA
+
FE5;"0;0().:1G,/=%<GFC8!%08$/&09?):/8#1C/1/;
@r9668
TCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCC
+
!8!.H:2/BHBG,2,H<@="&$A%!;4'B0C6E54$3$:9D*6)0!9++9?/2-0@,"/:'F'=FD3?9,:CA0)#;;52/A-<1>
@r9669
GCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTT
+
#!=-H0=.,*9FB<F.!7$%3D(:="(CG;C#A%283@35/36"="HD/=('%+D))(%#?A14D
@r9670
TCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAA
+
F1?6E'5"$+23F3)G86"$"!-*&$D;3DB-"H1:(<H@:!118:#D8-,@47GE4:E"*11'3&+3@":0!8E1&
@r9671
CCGGCACNTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGNATCTCGTGCTGAAGTGGCGGCCTCTGNCGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGCCCTTTGCTG
+
>3+4@834EA:/'E3?@8%C@16,5=F<.--C@0+BC5E96=..12::'CH$C3+AE=4-#8E88-H6FF+:(9;$+/?)97<$7=#9@#4%$4$!F!F(-C"99D?"#'0=<6A=D5$0#7<B"B22<@E2).8"'A4F2/B!#B93#C(+3,D"63&."=+E7*/'=#-A!H3<*1!'F<@B=0&)<CH2<?F+(+($4;+=<*;5$;>$C;;#FF4B#'>4AA@E3-G.E-+@:56&90CE
@r9672
ACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCG
+
@;?#<'F=7(>"'%>2=#1D77D)HE=5$,(F<(1F/9#,"3+>58E3*E79B93*(*&8%6!1
@r9673
GGCGTGGTTTAATGAAGGCGATACCCGTGCTTATAAAATCCGCTTCCCGAACTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGA
+
2E"5)A-)$F8(.=%6:3@E?G,#(.#&4""'0A?$!'#!.(4%H5GA$9&EH)F6!"B%->1>C+02!$F*(>F"4!4HA("":E;&:%,G4&./<97A2'$<FA?
@r9674
TGTCCGGTCANCACATTTTCCCGGCAGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCANCAAGCTCCTCTTT
+
#??52!%.0D3@(3/C#DE7E(F<,7$7=A5>F8E,F5E7@B9/2?."8#/0"4A<.#.):D:")DD#74897B(*3
@r9675
GCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGNGTGATCGCACCGGCAAG
+
<6"%<-H!C4+&5C7.)1.;A'!D2@E()--?9+.</%DA/*317#2,EF)*8H/+=(*%(>F%
@r9676
ATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACNACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCG
+
7:!):;="+<?4,A2HAF/GG;*'*C@;.AG(81:92-*4$>F%.B4HG*F>:B603(?4A:#>:!GAA7E'*G0HH#/$=1"8-6)C.'<#>H=?"
@r9677
AAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAATAGAAGAATTACAGCGCAACACAGCAATA
+
G<#C)E/2C)11,?H+25%D%G>@1.+2@05EF&5"3'67,A="5B88/:+.<=7H@0$C?&/$F-%)E(7D>+1%D>DCA$C>B/7)2(=1-
@r9678
TCTNCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTAT
+
&%#+*#"%$'#*$$*"(!'()')%'+')$(#)+')'&#+!(+'!)
@r9679
GTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCG
+
,>!377;G!4F80G748+4<D?73#2;@>18'&-:4<H0,,G-53
@r9680
TCTGAATGCTGCGGTAANCACACACTACCAGCTTTCTGCATCCAGCCAGCGGCCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGNGNCTGGAAGGATTTGCTGTACNGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATNGA
+
$#+!&"$!+%"$#&"$*)***$*+&%'''!'$(!+()%!!#+##!*)$%&(+#&!$'+*$"*'''%!$*$')*)*)&$"&%)$"$!+&!$)''"(%)+!%$%#)(&!!''%%(*#$!"+&)$'"!('(!!!#%*#)##)$"+#''%#+$&$))'$%&'%$&&+$$'"'#*!*#!!((#!%+%")"!++!((**+*#**#%%$$#$(%!%&#)$'*%*&')
@r9681
GAAAATCCCCTAAAACGAGGGATAAAACATCCCTCCAATTGGGGGATTGCTATCCCTCAAANCAGGGGGACACAAAAGANACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTNTGGCGAATCCTCTGACCAGCCAGNAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGAAGTTTGACATG
+
+B0+9B6FC5!GC(G"(-25(EG"CD>)1+'%;2(&B8,+;D.1CC&;%A?@,/9(7E5>>#$=FF,#2;6-(D&@:42A"4.(:CHG-2&.->>9)0(7*.*BF/%)(BE2=9('"?87?+>/(?*>**1=0E9>G2!2+>7514>0!-?.''24?0?!5@8;(;C,,&@8;&3;F3)&HA)>-<,409%?7/&;A92/FG&:14:-+/2,3/H6;'=&,6B.GG87*$(3=@$218G*%(#+G)G(
@r9682
TACTCAACCAGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTC
+
4;<G@D@&+0"EFB:D&/9?-3(H=3>5>G;//H<A1B'06#/+F84#4*A+.C"2+.,*"A<**9@EHDE;F3H*)1
@r9683
TCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCACCGGTATCGAT
+
,HH./-=",9F6%%4#)>/0$10)7(7#';B&:5!#+<12+/>&0$/A6@06E+C'>G4!?"'/0-2-"F7%)
@r9684
TATGTATGAAAACGCACACCATTCCCACCCTTCTGGGGCCNGACGGCATGACATCGCTGCGCNAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTNGCGGTCGTGGAACCC
+
0%,H9+0:7FB:@0(.(=/,.8A3#+4206(7"CG8G*"(:"%0;22DB%1'+=+B(A==)HH(.0,/C&E+4DD9=-?6BC!/D+-!G!(.6;$EF>EG-)@(5(@3H$;.11+7B%=?.&<C
@r9685
GGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCC
+
>558*>A=6,-%%/@%%'@E8ED9+??""(:>4888AH9954-./2E6?$5="<B7)#.429E#"?(E@=3DC=F5.7"-<=-'5!GA3AA,*8!A5E=(8%A-6
@r9686
NGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTNCTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAA
+
)G43(8(*D8@BAB5?#H?52(9D&CD'1H7=B"D6#)8"6!!1H46GABF9:>+8<??3,('8-FGEB!7='&#*(97!C#*DD5$?'!@FB&:03=6CF-#3;9A$52%";D%6=1G:)C03+*5&;.G(GC=D3,?+8"5:+*(.8-D+8/5A0E=B7HE.5>*6=#C/$DF.%46G3*+F71)E>,#')#$+4,F$*H,;2%9.!(F
@r9687
GGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTA
+
!40'-#$'$C7<9)*650+@G5?7%7D<C7&7#E3,1-FG18!4H"BB,;7'F)9;>(-7%@=.9G:2G@=;#=8&H:?8A::$)10C&5=HA;8758BE%1:<;!D?2H/<?.:#"6F7C<>;&
@r9688
GATACTGGCGGGATNGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGNTTTACCTTACCGAAATCGGTACGGATACNGCGAAAGAGCAGATTTATAACCGCTTCACANTGACGCCGGAAGGGGA
+
0!.0H.%:05$:#24:/.)D;82+A*2C2&?(5?E.37,>$?C%<+:3>-BG<1>:@%<F%%1D<&8F$:@/>BE2?H,:6;'D03"<7!.ADF-),+AF40*F#%2'*0D678%)<&;0->3>!%)52*%*$*F4/'"&*):,4$2,(>,+C.<E,A*C+C7$"#=>@50417C*"=C//C.E-!FD<809+1??,!";12EH>G#;&'<>;F!
@r9689
GGGAAGGAGGCGAAGTCNTGAGCGCCGGGNTTTAACCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTT
+
A8+:1'DG$A?&@G<)8#2<%G*A=<$%F*E6@332A>!.'=-%F3C=+,//A+>EC5$<C0H@B)<H9D.3&/%:D+58<<'&0*G>>**A2<(4H/4=A'E)++)"-=##B):(67?ABH*=,39!6>@3'63-!2281+F2")%-=202D"?.B438A-)%-(C
@r9690
NCTGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCATGTCTGGCTATGCAGAAATCACCTGGCT
+
"**%+*+&*#"!++'*&)*""+#**"&+"+&(+*+++")"+'+++&%")+"+*$$%")+*$$*%+(&%!&&#("
@r9691
CGTAAATCCTCCGGTTGCAAAATGGAANTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAG
+
H#.2FD,F/"3<3082=!$9)8'F5//<&CC?G=4,$5%A"9,4D).99E68:1=$3;=--)94%?7/0&29,B8#BF2%?;2:;B?'A.(,D!;"%:1=.&3;>,9>G>*2#GD(CE?-9CBGB3%B6A=-EF6GH=%/3!+47A56!.9!"&*$)E"C8=&.4>%'(,0*C;C9CF;0F?!9:H"19:
@r9692
GCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCC
+
>5)$&&'/=>1/0!G1B<7F,)/,421C>=E8H7%*B<C??C=EFB;')G
@r9693
CCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTNAT
+
=7?38(2G.0D-F10#5486=<:13%&F%A,&B8B</%B%0A:
@r9694
GTNTNACTCCNGGCCCGNNGGCTAACAAAGCCTACGCGCTGAACGTCAGCGGTGTGGTGAATATCA
+
*#)($%!%*%)&'$*#*"&!*#)'*(#!*(+!*$$&"!%!&'("#$"'$"*''+""))"('$))(*
@r9695
ACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCATAAAGCGACGCAATGAGGNACTCGA
+
>)36H7!D%>,E=D:4'F?32>$,<E<75*=+8,3$DE&=2/A#!C23F%*8$:=&%@#D92E)>#0D=(?>)BE55%78::.A+FB9-!&/F)>71)8F/2:5#F!)>H9,53%0(5<H)%%)F9+="0((12%!!.,,!BE+/6"<CB262<D15%7?4BDG/3C%<C,)%'9*DC(
@r9696
TTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGA
+
HD)'/E&B6<;+,4A(+@4+'=0'EH+&"049F?=;D@&>=/$@,."
@r9697
ANGAGNATATNNGCTTNAGTGAGGAGAATAACATNACGCAGTCCGGCGGCACGGA
+
'($$"))%)%#%'#%!'&#++'#'&(%"++$#&##%!+!$&##'*)&+!(+%+!(
@r9698
CGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCGTCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGA
+
9:?:#3*+79,#:1=70!,D%721%*1>--1;3BBE950;9(00<DF&+?D/@>')&<0D'B):H-*7*FBC8309:@;0%7-4.FA-H*6@%F=H#
@r9699
GCTTGATNGANTCGGTGTGGATCCCATAAGCGTTACCGTTTCGCGGTGCCTCTTCAGTAAGCTACGGCAAATGTCATCGACGTGTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGT
+
)&)$"*%*"&!%++&#*(*%&$!)#&'("%%%'$!(!*'($*&&$!(&&&*($*+*&!&+&%$&%%)#+$"(&')$%&+$%+)#$%+!&+&#)*$#)((#$'(#!*!&%*%$#+)%()'*"&++'+"&*#)&#(%'*"!)+($%+#+!+%!&+''#+#(())$!)%**'+
@r9700
GAGGGCAAGTATCGTTTCCACCGTACACGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTT
+
*$>F5A>9."+F!6)E.3""AD,0#63+;A6E#@&AC;C/B!<4%;;26(9*5*E9%$;@DB(?.E'=C3:///"=E*)#(HB:<:=91-2-1:!#E>8!7H)H;0<&(
@r9701
TNCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTNGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTA
+
'),9?:G;D.<G"=G2!'8D$F,:C&G>5#.G;'/BB(@B#)/?/?(/9#?)<E%#-H2)75C97982-6**0@7CH?F/F;+&+0
@r9702
GAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCC
+
.1(159)EG1F%-;A'5G!2(C*75'(:H5G!/?D7E?F<&8G/C&031"#>65%!F&;83D!C.-(5"G)4<.=+4E;4;-/?8#ABC4*48!-*+>A7/20(H?,9)4C8-
@r9703
GAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCNGGTATCAGGGCAACTCAACCCNGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGG
+
-:':/CH0832F9GDHE00#A0'<,?<4>,+F8;$:2D$?,5AF3@2B")@!:52;*'CE7;8DC0((,*"B7=8#@CF(6>,@>H!=@4$4A;>86#''C@$@1A>5+'5/98DF>0H!?65410/.#1<*D'#>1=:15:&-3(-H/B,=!:6B&"&F0'A(3)D$!H?7H9!0=85<:5?',%84=$+
@r9704
GATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGANCATATACATGG
+
3E&B,07B!B5,%>1B/(#8++';0>!80))#/62?F@HB#4A7FHDE:.#.>!7H9<#D@%4"@F<+@%5,'?0.2D>>
@r9705
AGCGTTATAGGTATGCGGTAANACCGCACTCAGGCNGCCTTTATAGTCATATCCTCTGAAT
+
5>*#"";3388;>*AE'9<+C47)/++A*D845G63@,77!C5H#8,9##=(?$.,0AE42
@r9706
CGATGGCGTTCGAACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCG
+
7?DAEF>=995DD)E@22D#<*1#D-;0&(F9%AC8G9<(.,!A=10H)A"'@/,E@'H&>3F6+6)('+F<*H4AE.<*(7EG;E?
@r9707
TAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCA
+
#>2(E87=%?5GG=BBB30'/9/0'0FA4"#4?%F.6,1DEFF=:#C4,H7*BH:3$<%4-25&H-&'?9*&<='G,D-3(,C1EEA$-A60F1@A=;.H;70%171:!!.$)G&+7!E>(*1@$$F
@r9708
NGATTTGAAGTAANATTTTAACCGCTAGATGAAGNGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACACTGATGTTGTAATTGCATGTATAGAACATAAGGTGTC
+
#2%1C4;.*)-9C9&8:?9B0=G?;E;&)%A#0>-E/:"$:5"B)G1;'4+F8ABE<(936#'=0:<CB7*"%/:!-#!H+C!6>F7+%.:%7-)&2,!#7<.8H'4=>)+>AF!1!H&'37--&E,8%96F,C()3)!4;$E!H!F.6<"?7)A?<?;4"HD*DC6-9!@/;E6'B#:6@
@r9709
GCAAGCAGCATTGAGAACTTTGGAATCCANTCCCTCTTCCACCTGCTGATCTGCGACTTATCA
+
7,;$CD0.".E%$))."%<-#;-.)#&.0D+*2C):;C69817(?"=,1%E$(-@.6G>4&G6
@r9710
GTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCANAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAANTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACNCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACNAAAGGATATTCAGACGCGAATGCCTGTTCTGNAGCCATTTATCGAT
+
,#H"F$B=(G1B@"!!'3.,,"=5&=,BH4+0<-8-.;7HB++,B.*->?A9B$*F(+.C*89/"4?B0EA3-79)5A3B%E=C/@:'#<<B;6=8;@!5$#-E%:$8B@'E2C8>D/DDG=8C=/"(10'*6D30/1$!&:"8A<#+9*02.2268C"5-?F3;(,/<4E8G')>."9D5+:99(7$?H*?-5F2(2#B#:=$%4>)5H=59,)<4.+#<'A<3#.7E$6!5G-G49,;2%0D=G00B(70:3!?*<&9*(*";B99E=.2,./$
@r9711
CGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGT
+
%1&,5>2>#@DEE(##7&E&H&B$:A2+F3<E(:5.2C*@"A5(G-@'==:(;
@r9712
TAACTATGGNTNTGNGTNNTGNGTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCNTTTTCTCTAACTATTTTCCATGAANTACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCAT
+
"*%!!$$'*)$)*!"'$$!(#%%++"!)%*%$*%'&!+''&$)+*%))!(!"+*&'''(*&&)'++&+$)#!##'%$(+$+"$!)$*$'$%&(!('&*)%)'#(*#**%!%')**%!"!)*(%!)#+)(%$+!+!'%(#!"++$$((%$&)$#*$)
@r9713
GGTCGATGTTTGCAGAAGCGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGA
+
8@H4B*58#;B%7*1<H;;>B>BC4'0@(*>0%<3"8,&@*82<9<:?+C*37?'@64?9='@&>9@2=D--52274-7!(0E6>(3>!+..*&G5@AHA=(1CF5<G2,:)'!710:>06&5017:!2F"FGDB7$/+@&F!A=<))+B
@r9714
ANTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACC
+
(-.864&E:/=A:#)477:'"2':'8B;EC5@.;A<:8?2"+A!(
@r9715
CTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGANGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATNATCCAC
+
12=+@44&-+B-+?B@#/C&/+$&;FHHC#*%1!:<=C<!BCDD/G0$#6=&*,&D,-8B3H<38""$@8*%1$:)@%$4!$8+G5<=(AC2:@'!B-?**679#-%/3022?:FF>23D)A"&&C((
@r9716
CATCAGGCTTTTTTTTGTTTCTTCCGTCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGCTCCACTTNTGANATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGNCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGNCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCA
+
;E23!,5:-E.G27C11,2D%G#94<456>=2AC*D%.E)""/G2."9<&,C(FF23G$+8C3!.>)4+-14A08),DA;9@C5=+8;!6,;./H/A?A8$:571@:C5,F67/960A3?+G8#*+H?D)>6-)$;,C=#<4<+2.;?35-#%3#2)264FC107(*2-4E:2HGD:*;6#>H7;$AF%./)8F,GDD*.31?5)E1B6="E>%6*%*)/'63.&2*.D@@C5#73D"($:5'.>6B*;5!)727-G!8@B;7HC6#<)*A<7*$'2=G8"'&D&7#3<46&%8?
@r9717
CAGCAGCGCCTACTGCCCCTGCTCTCCGGGCATNCACGCCAGCGTGAANCTGGTATCTCCGGCAGNTTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAG
+
;<2"..=2;(3AGFGB7%@"G0<E26.:!(7-0?96&.F1(42F715>3D?"0?;+!0G)/H@82>4,3@*+@1?'C>0'H@4E:E:'*8E$1)8D&8,B1-<7@H&"<47&C$6G>:
@r9718
CGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGG
+
AH/"D41=*?A#H>19$:A8)?@!=&9-G3G'46E%4#5":G&6*:C2HD<16D%FC(4;7.?A'0'0+8!?>7"?>GF>*
@r9719
TTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCT
+
C799G!GD25+$H?:DAB:EDG6=2++39H829;F&C1E,A+F>+G"
@r9720
ACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCT
+
DF0D$1D'/'@<=,EHH04#8&FB4%-;H=9:!".4>4?;B=:/>#91;4D**5
@r9721
AGGCCACGGTCNGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGG
+
?E"6:+B"(E+=>3CE-A+3"1+!">;!+9*/,%G,?,B;D;%;(.CH
@r9722
ACGCTNGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCG
+
A*'>1:@2#-!'?--GE'%CA-,AH*,G#<+,+!8@%==/B-%#.&:7%/!;7>:/F)3F6<&#87)9/F=?5:/F8?&@B+
@r9723
GTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCAT
+
>7G?(F+7#=/G,(H?=627>=F.+?:.)1->+9'(A:6?&@#$$3B$H&7#;190%9@D;576A*.%C4BFDH)H@?)H2)A/H@0H-<G+8,3D,;!/(!7/2>,C-?94C-'=B2G=%<2=13%&!
@r9724
ATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGCACGGGAAGCCACGGAA
+
1?C48,125!53F3B/0?:/708@+7D'EC#,<G322-8<G@+@#(&#?$98.=#@?
@r9725
GCAGCACGCTTTTTAAGCCANCCACCGGACCTTCAATNGGCCCTTCGC
+
?(%+.E(;))34F)*5.C8&;5!&(98#&35F8)D"$?&07E>.H7#0
@r9726
GNGNATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGC
+
''(+$*))#+)$#%%%*(&&*'**"&*'$#&)"')"#+'"#%#%"&*+#"'&)
@r9727
AAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAA
+
-G#!%(8=.1$4(%'?!.-&GC;C7842+-C(1&3$3;/1,&>9.0'+"H9A"B'4-5F1E%A!3"
@r9728
GCCAGCGCATAAACGNAGCAGTCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTT
+
CB';8>:HE9<3<=6/"@#"6>,"7.+*@=(5?$$"1$+H(+C.;G$)+&=F%1H21D?),/)3,:*<A=",*E*(-2.D(1*04E@F95.>:B("-;D@???=';>/):=#*35H476&3<-G3"E391.",ABE$7(*2F2(?),H<5/<;.<).E:@==(DE)G..F*?6"-A;B"??(9?7-*+'F%?:(A).1-D"77'3!.?6;*5$#0*"0!,:23)
@r9729
AGGGGCGACAGTATCAGCCTTATCCCATTCAGGGGAGCGGTTTTGAACTCAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAANANATGCAGAGTCTGGTCNGCGGA
+
@53&5,1.-/4E,31-!;/F(*#7<;#AG#6+DE&.)5$93%(;F&F.C<!8".&,C7#*8#GFC(:#;:>F7C>(*E#49-E,$>%B>%E('>>$8>7*;5'F=G>01G!)C$F->49;/62D68"GA/C0C)7:1G;1G)55&4F@,
@r9730
TTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAACNTCTTCCAGGTCACCAGTGCAGTGCTTGAT
+
;1@0**1+(G<(D=3&HA739#4$7E>8"!:&E'D15G#?"@!&B><,DA2DC/'H$&<066=/#3?,/!G;AB0*<&:B'"6=7G2B4!&,!7GF2;.:+,->""(B01+
@r9731
GGAAAATCCGCCTCATCNAAAACAGCGGGGCGACCATCAAAAA
+
:,H*6>,%=5-$<E+&BC*:($0AG#3>*78@B:C;D0>;&"-
@r9732
GATTGCGATTCGCCTGTCTCTGCNTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCC
+
*H:H2(/;)2"*!<>B7,6)10B*92*,$:9.,%2(%#?/4%,5G,B.F:!5<-;93."EB'%5<HE6A81)
@r9733
GATGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACC
+
)*)*2.A62.2+<:D('9=3G)-"*%(DF1%?"8>C!:71@B854-<,1(6%*G
@r9734
GGCATTCGCGTCTGNATATCCTTTGGTTCCCATACCGTATAACCATTT
+
H-;H8;=:->A+0>C@%1'"*GB27C@H,)<B3<3$'?56/7?0+,==
@r9735
TGCCCATCGCATTCANGATGGCCCGCTGAAAGGGCAGNGTTTCCCAGCGCCC
+
'0BE3#':,&2F;-F(5!#&D"@G,()8DEFA-3D41,.9F4$"G?,6%>HA
@r9736
CAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGAC
+
110.4$)'>2@*<08$E)@@34/*>"4*<)$.BA*7"D>%$6-CE=>G2$9H<838'@283?-AH289'?!<;!(B:2,D!EB4?A"D/9++:;4-()06-4(@%H%G.AE3?><9>-+FC)F).$+F<8<5G53&8"HFA4D5F(>?8:";C<HD,;/13A#H:A'.8#<"&3*F%0.2*@EG2>E!664H.25B/0";=@7&##67(7>0354<AB
@r9737
NCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTNTCAGTTAGCTTTGGTGGTGTGTGGC
+
&8!;((F"D!2&64;*;-?;?'(G="4,:"-5?=A,+B-H*%$)7;#<#29>A&C<C>2C7B?&CC4=%'<;F2'@A(E3-9H90,8A-!6@A1.*1'$.9*2+&+(A8,2=&HBC'8CA*=B4%!@'H676C0?>F+*2#,=>AED$6-)>5+@+C&<=<EF/'969(>217&!,0185%4>G*2/#
@r9738
TAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGANTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTT
+
?*8#=7!"!8C@8@+H7%D??C2:;&=,##!4#(GGEH/$!<9GF'%E/";43*49>&D.E/5"F.'(:ED=564F'.D0:5&=F*B2(3:F?G/8##1(4!(A>5$&C:8AD!95E5C,>9
@r9739
TAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAAT
+
9;#B',<A0-,:8705C4=;2B"5$G-09#)/)<2<099#F&0/27G')5.26EE%D;FF%.C;:@*%)#3A2==,/56#+-D
@r9740
TAGCACCATTTCTATGAGNTACCCTGATGTTGTAATTGCATGTATATAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAG
+
0?;BB5,CB-<F!/-&G)C9;+CE.*1D*#&!4C>>29!"*)8%36/6/G$4?8@)4<0;%<:-($.!*F(1%18A37%%<!FH:
@r9741
AGATGAACCTCTGGTTCATCGAATAANACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAANTAAAACAATTGCATGTCCAGAGCTCATTCCAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGT
+
+1,*#E,F0*H34=6'DE<+:-F&E=EH='?C&45F23")9*7/H7@385:.E1%>:5CH4:(A9:E5=:2))>%G",/99=:#@)"-9,?;25!39)>:H15!/=H(5E75E1.BFFA76>DF4-(%A.7>0$F.50,#?B+*F<3#<<)C;(2A6
@r9742
GNTCNGGTGACGGATTCAGAGCTGGATGCGTGGATGGAGGCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTNTGACTANCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTAAGAA
+
'"#$!)%('!++"(($'!&$(#*%#$')'*"+"$!!$$"&'!)%*)"*#()!$#***("('%+""(!$$*%*##%)!!($#)**!%%+("&"'#**&!%+$&&#*!%!)&&&(')'+$#")#!('+"(*%!+%)+'$!&!"%&!&&!++)%+$"$##%*))$&)**##%"$&)($*'$&#$"(
@r9743
CGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCT
+
F/3/3*5B*8F,A!.!+C39**C4ADGA?@B890?9GE*<0)
@r9744
GGCNNCATCCAGACTCAAATCAACAACCAGATCGCCTACCGG
+
F':-5!17=5E1:&&@7*&D+2&$*F<51>EH5+(-(H6G81
@r9745
NGNCNAGTNTATNTCTCCNGCANGGTTTCATCGTAAACCGGAGTGATGTCGCGT
+
")#!"%%)$''$!(*&#"!*')(('*)++$$'!((##&%&+&*"+&+#''%)(%
@r9746
TCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAG
+
/+,+#-,@HC=G%;='&00)9B/3=EF9';"&6,9?%=5,
@r9747
TGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACA
+
A.0<D@8(H989?D4,'@00.:'?-0?B%=D-&F<6@FA'5!$GD*
@r9748
TACANGNACNATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAATCGANGAGCATCCTCAG
+
(#)()%#%&'#&+"%+!)(##%(!)%&&)($*&*"'#!)(&)*%*%$*(+(&+%%#')"(&)+!&++*''&"('&&+&'**
@r9749
ACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATC
+
&HB02'1:/#!H+*6F45B8='(&2<!BG94A#E<=89-+>&-$2)'C+B232B!<G>0#'#(F($'($<5C&"0/19@,%C$A//;(!*C3D62F$45#(*5
@r9750
ATTCCCGGACCCTTTTTGCTCAAGAGCGATGATAANTTGTTCAATCATTTGGTAAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGCAATATACCTGCGTCATAATTGATTATNTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGT
+
@&#17B+!+0G>9-4)E'=A36;.'$**?$"!E%)"/D?4&"+69$4"59A<-CF:*H?+&(>*>.G$@G!5=3A2H;>H5#;!+7F(+7*;F(D%(>9"D/)$B+)5A10-!'E2#&F*7@>B=2"<55(A=(G3*5+1<-$=6+,'H<#'5(+;?/FE2<F><CG<68F!#!?@!"%D0<4??@+*%23(*9G#!%**3@>!7&=F)@2,>"=G=&H"/0.272#%&)2(#8E#>%%:*728G@C&0)F2,1(*:
@r9751
CCAGTGGTGCCGGTGCCCCCNGCATCAGACGATCCAGCGCAGTGTCACT
+
:/:E$A&BC./4H&18,:=.B:583,/C%9#>*;:/;?G?-0A$*-@6$
@r9752
CCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGT
+
D%)(32;/<@B'/?9.;5/6/,-#3/:('=:44<FB>:32;GB/;;&,")#B3:H1<C<=-#>B<8;/B136>830(7;*(>D%F57'5='$1A=%8'207',5E.B
@r9753
CCGCAATGCGGGCAGGCAACATGAAAACGCNTAAAATGCGGGGATTCACTGGCTGCACNCTCAATCTGACAGGTGCCTCTCACTTNTGGCGTGGAGCCACGGATGGACTTTGGCCANACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGC
+
(&$/0A9%,:""@B344G-0/(?+1DA9>%)$"#H":,0">,38?$D30H)<&39.DA+%=1!:'#'7)7'G$#<@43!715*F.B<'0+18G<.,+('$5-C%&@54H?G:H+)7'DH$$3C'"52;)6<G?E*D5A$G7,%'6BE,7-,'*7-D:62*4--,$E3H,7!5?/*3&%!%3H1.?0,=<$4,2A'&4.=.E:3#CH&=#F2&(D;&"?%BD%:&;F41.D(FC4307-8+8?
@r9754
CGAAAGCCAGAACTCCCCGTATACAGACAACGGAGAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTG
+
$.3H-(3$"<.;@#,CF6#;,<6:%"C;'=B,2(7#C>1@/)E<!2>@65!:G*%,F9@3;D><85(#CH&-#'(B+1="+
@r9755
NCCTAGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGC
+
)%&("+%!#$!$(#%+*%&%##"$%##)"$)")')"+*("%"(#$*!%%'+#*+'!+**(!&$$('()))!*&)#**")#)'!$%)&)"
@r9756
CAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTGAGCCGCTGATGCTTGAACCCGCCTATNCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGNCACTCGCGACGCTGGCGTTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACG
+
GG424)D@@F(0+D04/*"'(!C;E8=219##,B90;/>@0,?>B((G8#55A@3#!GG(-%C'$+79<C&516HB?1&(%$+<-+3$$1+3B055.#"1HH.7ED("5);::)$$D9E"!1.:!4@FH3.22*@F&!<#!)(AA>)D'#B$!*@'8E&/B?5F/#,9$(93D;)!>9A+%&?%8A.G934"H!7*8<86*6)H"?7#@H-'3/+*74<+8A=>F9E>'?/(@'F!C74,@=<A@FC!GA>0/*D7'F@&,,A/89+CC2"$2/53."D1F;/
@r9757
NACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGA
+
%-/?9C,9G*75*5D!E35-.D;F@&'A(%0,-1../B'5F<3"D&BH9/63(
@r9758
TATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGANNGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATTCAATTGGTTATGTG
+
68/?(?)#)7,E!(D'C+&9F@%#/(D-78"8&E9,?F*(?&H#.=&99>8"5041@;/B?C%65'*?,B2A2=6?4;E74=,/+!=A"@G#,:#1!H<,</
@r9759
NNCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTC
+
'!#+()!%"%)")!*#)#%'"(*%"$$""!"!%**'(&*)"#($%$%*!()'%&*%)$'!%#'#$"(!"%++"'!$
@r9760
TGCGCNTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCNCAGCTCTGTTTTGGCAATATCA
+
@5:(4@%C6;9$$?'+B/?D@5F"C->(H!?E&52+D8,?3)D,E/92>A9D3$:$">=3#854A23,&!G<$';?"427!.)%=!"*<B8<46
@r9761
GTACTCGTGATAATAATTTTGCACGGNATCAGTCATTTCTCGCACATTGCAGAAT
+
33B+$H$@?:83&03&>H8=@,2G5%4&%42&*+7?F<"%';9A,B1/5#"@&#5
@r9762
CCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTANCGCGGCAACNTCCGGCGCACAGAAGCTAT
+
#361(=2F))=)3)&D.8,2>A(33!%">52>2;GC4(2>BF#G!F8!49F,="GG.8F9B=3D7!.@B;@!;$8,=8G223?&.0:(*1+97%BC5B26:%-,847-)@<C<:<)82?>D6-%<G?376;%H-4:);,H2H-?/8.'A,):<3'3
@r9763
AGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAANTAGAGCAAAT
+
H@*@+E,/%69.4<*E>8E@1B=?9#$A!BGFA.:B5F#&+ACD/$"=-H-,/C:F35F#6B!-&G;.<B<,&C:$H3'=D%,262A.93F*3.)EHH0+/!.<A$A0,HG&(;>%0&.";%>1,%19@
@r9764
AGGGATAGCTCTCACAGAAAAAGAGACGCAGAAACAGCGNATCAAACTTAAATTTCTGCTCA
+
.-/D!2&6G-&2)=$F94('!>$$5?:,H.2D;$;>:@BH&?>+.%C4$B=@)1/C/E232A
@r9765
AATGGCGTACCTTCGCGGCAGATATAATGGCCNTGCGTTTACAAAAACAGTAGTCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCA
+
'6(1<"G=@EHH.!+$&0:"CD;H7B%$<,2,)@2*4:151*6#/<-5G"/;46>(E@B9E2E>9.%.D.HB4!H"86D3EE<H>*%(?B*-82-5#E3:@G3G,044FEG7/+?,!0D=F7&<,
@r9766
CAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGAGGTGTTCACGAAGGT
+
$<@"F61("B)&">=,=$).=8D39*60+D($#AC+.=,,5:F1?=*%;8#25EEC'$&0BH?/
@r9767
CGTCANCNCGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGG
+
$)$'#*&&!(*+)!$)%"*)*$*)%&%+(%(!))"*%%'(+#(%"&!##%(*%!$$"))($$)"!!&''#!%)$'
@r9768
GGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCNAAAAAGCCCGANGATGAGCGACTCACCACGGG
+
&9?*D",1F$"%+%*0?1")'%%"002%;')F7=(!5;AH6C441,C'?A(1GA)B3=<6E!.@5?%G3GDA"##GH;;)$DB977$+/152,DH78'+*6B=D";('=2E30#%0):G6>>D:1ABC.&B5@@':C50583<8.@+>(@F.+7G1"A.72(<E18:4+F@/>;$@=4?-(4E<4E9$(&DEB28;.$9>'5,A>,96B01;;(5B$!?/'F)94$"GG+9%%'>HAC4@2D)BA+<G%8'
@r9769
TGATAAATTATCTCTGGCGGTGTTGACATAAATACCNCTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTNCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGT
+
*?,6F4AHF<E%G+%&+-6?2$C.,EE.)D25;!':#B=$B80++:4+G$,C;;*9.6'5*122@(!.!6+B*-;=)*E/-1<;4,65H6#5.<0H&:;7C4;=90@-)"1)B!B8F:7.5D,%G%.,4(1(&D9E.&H$FD(286)80@.4$5)8?26#32<(D*)3B+7?&A4EB(,%D2&#AGF%E)6:"6,)+05-@)".H=<)<8*?((%DE*(6)
@r9770
ATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAANAATTCCGTTGCAGATGTTCTTGAATACCTNGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGC
+
.8B#7F0D,1C7'7!=#'4F6-/!=--'*%D7B3:-?A.5#)D<>;43$>#:24B8(6G30GCC!*2-6-:E@+H*/H#<;C)6FD.5$C6?GB)@C9)01%#(-0=4$@='DH2#5H:*EBG33<80-*/,"0.1*$EF*3BH,9-@B,3EG:$>)-
@r9771
CGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAANAGTCAGGACGCTGTGGCATTGCAGCTGATTAA
+
,(%:D(81D/4D$,083$C!1)(570(@!G'HG7!<B32;:.+?&00B.<G&5??*FCF<,9@F(+!A2B/;%$F1A#@=97?9D(
@r9772
AATGCGCTGCAGGGCTGACAGNTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGNCTCTCCGGATTAACTGGC
+
B*8+(**@4;#2H!>E$D>&1D8>>.D-3015*B=!&;EG=49.9&GEA5D8;*,3D?<$A7:H*1->700+>='11+3<,GF9==:?GC6*34,@->5?C/
@r9773
CTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTC
+
G!=D?739>/;'"283AA=39#F-G,<%,(:A)=F$+?%B?6<48B#H+2.AB:!GG+;DD
@r9774
NTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGC
+
">E&BE@G-F"G*:GH%(3);'6GA@7563:H"&>';&B)C*H/CH-),#0CC'F!G-41&B:,014#H0?A5+;.8$7H$55+<9?.519F;1-*3(4*8:!)(H3%0C#-1A!#<#@*CA1>*G&3@$FDH3:8
@r9775
GGAACATCCCNGTCCNAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGATGGCTGCATACTAACCGNT
+
&**$)%)(#('&$$"!(+&&"'*!+$&"#!#'%%"&!'!'#*$"&!$%%+'+#(*#))!**+)$+!&%)!(***&""
@r9776
TCAGCCAGCAGAGAANTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCAT
+
57>!#'D:ABH)9>B*F>2F8?79&EH>/=8)3!89.<E900$F?%?&B21&5@A#)+0C,:H);FE.!>DA1@7>)FH9F.5C;02B@/8C)5$;#;
@r9777
GTTCCGGCGATGNAGCCGGGGCATTGCAGGCGNCGAACNAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTNAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCC
+
E<-H:&1=.#%5*?0C86A31>62.>?!'$.CH@$$3D:E;G;>-3D!8@,D4):CA!F'/C=<EA8>",E=8GF+>E"&*:!9FH8=0)5((D7"!1(@@.;'""982=GBD@(=B&/7.9G9E9:"E0./H#'7@&$)&,@#,B9!@.H6.,)"6/!(?*!5<=$,$GH!@?16=2,&F;C;%F=D%)65&C.@<$+$G&886F=>.8?@59-,:09=H.89(>!,$7>/F!1/>(#$AB)>F$"72@:#36F$4(@=9%&'5:@9E87BC@%#,AC?26"D-!BFG)!FC&3#$4E+4:*#02FH33*HGGH@<-,/@4"2')D97*
@r9778
TGGGTGACCACCGGCGATCCGGCGCTTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGCCCCNGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCGTCGGGGCCATTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAG
+
D<#@.?E4#4:GA%6<!%3/,;A2E7.B&G5F=:8?E-C=@H'0-),8A8C)F>&E!,A8?;?C!6.43903>(,=CG4667A,53<,B7#*+';1EB+61<,;+5?55AC&G(G=F7C#4B1H*()858,C:%0,%FD96''2*3&&715EF,!0&>>3>%.D87C6C#0)A=-"DD0<"D@29,"7"5C0@G5BE85."C*>2:5ED3H(3G><,#,3)<?A9;#7<3$G8;G($2<%A4F3</?H&<(;5.$
@r9779
ATGGATTTTTTGCTGGCCCGAGTCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTNGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCNCTTTCCCTTNACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCT
+
0E5=#.10BH+$(3*9-06#4G?7F//=)&4H!)6&H".*>!;E)!,"9/*6-?/?7">5-6G=(47*&:.6!?<(!8"2<8((E+;)8$-4A@#-+<$<H'39@<G0<*'3%#$(!>)82C%@<74G(.@E.1<)1@*8+%=7G3A%"A
@r9780
TGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGTTGAACTTGTTAACAGCACCGATGCGATCA
+
275:#+)1)HA+(/7E9:29*E)+1H1<7@F4,0D=;D+E-94"'-#$>9<<?D"9#>&$*868.@6%1DC:G=24;G(G>D8#:0:CF%>.E>#G@A66?.D!%H-)>B;HH;A%019B)A=FH%490"2=-B
@r9781
TACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTTCTGGCCGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCNTCGACGGACGT
+
A)<2-*-9)G><==&("H;F1=2::9:?E'4:&C86>+!E'.F!4&?GB&>4>&;<,4@B-.5?E:8+9$33$6='5@$<G1;H9A.#:088<+'?#=&4H-6150'#B+0#>E3:>'>.1!?>D.!,E+.!E4G%H:/,H.-+);!FC'*.!??@H,=(!$(F#!C#H!-&#-6>'>4G0'9B4G#'B/@,&@'5;3!?!5!8!7@3,@+%&;$7#209!!&G".A=#'=6<<=@+H+A:8+*:'4
@r9782
ATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAAT
+
3!1-%#3!>/&6#HA$9412"<,@/.C&?%;/A=B('/+./.@*0'/!D86C9G+6$@E=?!@G4=78"02G"C498>>+D-$>!+7=;6'1EH@D,EB$81*;!:")0F)6AF4$&F%15("#+;?'#8C!"2+#"!G&5@29;$H847G>7"%@
@r9783
TCTCTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGNCGCGCCAATCGAGCCATGTNGTCGTCAACGACCCCCCATTCAAGAACAGGAAGCAGCATCGAGAACNTTCGAATCCAGTCCCTCTTNCACC
+
D>B3(&*<28))E&A;%GD503!:8@/'"*.?)%@+FG6=$&&'('6,1'>EA="0=).*4H>1@(F&56<(BD0<-3',D2+C1@;7:%G/@%71.010-;7,0<6+3A-"32!+&A<670*.1-C.27$&'"C='*C/8EE,2EF/B2;0
@r9784
AGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGA
+
>-9)"8!?:*D#*%8-H2%0A#E:)9&=1HB6&8+108"0-'+"!41;6DF<#@"E/F"'D."*52A%%6?-;,C>9//=2>"C,:54#$
@r9785
CCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATNCCGCCAGTATCTCCAGCAGATACGGGAT
+
.AB32CF(&1/!?576HD>B/F"++8,*<-4=7!F9D?=#G;:*7E%@(83!H18E3>-D?'.D1F,?55>
@r9786
AAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTT
+
'(,>H0*49<G9!'1%E=6/D"C'?F>1$HD=(/E.>(,/
@r9787
CGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCGCCAAATACAAAACCAATTT
+
4GA$6!&)#0*'/41>)D>196A&;,**A@@#2G<(=H:'G6$4$8G%$A7&.%"3"<6&>E?.&/)!@6F)7!;&H
@r9788
TAAAAACGATAATGCAAACCGCGCCCTCGTATCACATGGAAGGTTTTNCCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGNGCGAAAAGATTTATGTGAATTGTTTTATTCTGAACTAAAACGNCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAA
+
=4A'=>E:@A0);/3,$35#&1@#3C*/9>@D%5..$@E+)/''D=D*@-.;DG4&G=*F.7.?E8/G#=5C>;.=$1C7D9CF(47$/"7#%<03'28';?4HB2.#,=9='1'*/$C!'82E:AG.?,3=)*+0#:<>70+)AA!&$B>!@C)CG/!A+BG.(;&)'.6B<<EG@0>7!.F#17;5H/H?GE=.
@r9789
GAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCCGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGANGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGT
+
:FF#@-+;:%8/:&,9D,4":@:!G&@9'5*9-803?=3>A:>=6%HBAD<@!E:$!";;A/<>6!E@'F24:BD;';.@99!?$3<.='H:<@'25-<,;:6B%@23.>>%%C&F;?0"=<>#4;-:+1C;#A:<E3AC>!-7A5%0@%#
@r9790
NCAACACTGTGTTACCTNGCTAATCAGAATTTATAACCGACCCCAACGATGAAT
+
#!0CF+&(,60D9F49?3=%D%832344+$C"84(&'G)3939?,%(D6$"2@$
@r9791
TGCTCAGGTCGAAGAGATACAGGCAGGTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGC
+
+/"/606(.96=H$<=!,*H383:!/(:(0'+7C?2):F+?/<#-8H<43#?!@;6@!*4%'"$7!2.**E)!A68&$@="*@:78*<.C)=80(0C
@r9792
AGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTNATCAGAGCGNGGAAACGTTAATCACTGGCTNCTTAATGGNGGTGGCTGGTTCTTTAATCTTGATTACGACAAAGAAA
+
05D@)H'73&'*8.;E3*2+&%.#4,8:A@?2E&4!<*E,4H-B5<5G$=G!=<2F+G4ED)8!G;:51@=9';3#FA7#/8;#D.:(G@108*27>9FEA/=28-CC1CH9-'";+42H=?15<(F=&B'$&&<'22/5A21="CH69C9GC;/GGF(?$@=F
@r9793
ACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAG
+
2-3.:B=E@.H?>&HFAA98.G,)-4@:6576!"+#'2@.*/?9E8'&@*5!5@/ABB466=DD/>9'4D$DA"C"&A5C>$C(H-/<F%7@GDDH1E@C@'')-
@r9794
GTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCCCAAATAGCTCCGCAAATTCGCCTACACGCATCCTGGTGGTTGACTGGNCTATTACCACAAA
+
:$F9<HD)"$=4?9(/+:+4444B%A=+@&/83@=6*&%'7%.?(B&04,!/+/#G!CEG>&+*E7!#4A6%6A6@GA*?:97DH+96/2?"46&/,.<?&-/),E-8
@r9795
CATCCGNACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCG
+
2G6,20BE7>3422F'/5.9!#A!.5;0GB0$G%*9,4AE?,/>H
@r9796
TNNACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGG
+
%*+9ED<A/A4=2EAE+4A'+=2C653!!?HH/1(5GB70&!'32G2"B+9A:E&6>5?9#
@r9797
ACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCNCAGTTACTGGATTAAACAAGCCCAACAAGCC
+
$*!#+)+&$%'#+"')$!"#'*)%"$+$+$!+'!'$#'&)""!#%#*$!#$$'"$""&*#%**#+*(&(+#((%&''$(&'&*!*!")#'%*)*
@r9798
GTNNANCGGCANAGCGCCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGT
+
$'!%$#"$&"#!(((#*+*%)"!*#("&!#*(&%!"!&"%&+*+#$*'*%
@r9799
TAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCANTGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTNCANTGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTTTTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAA
+
5<1'BA@<HG2G<<=6H-@G?;6F9F>3/C0&=B1,0(5;3*8@.'&&C"8CB5+01)1.!E5:0*%+!FE.@8,(=A-*">@F7;H'FD,2'6,:7-'/G;BB6<>G1<,=+'1,<>A;8<G5F26&?,?9DDGH?#,,5B.+(BG1@##G+55E5%CE.)2$H)>%>"2:@'+*1<1899=;,2:3>H>+1&A1.FD38CHA<DHE;F)5/-?E0)8@6F**."9=9/$B/@5867H)4$#B4.C@6G6;&.?G@C9D5,6?'1!D8@H.$.;#(&%5
@r9800
GTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTNTTTTATTA
+
0;.#(8FC640<F*6;H><;>*!@<(#%HGC)E&/,>73.2A0$DD@&>C:'775:3#3.$#"<;
@r9801
AGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAAAGCNCCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGANCGGCGTTGCTGCA
+
CF'42*2,7-G::1;0B5%&<78G=3*"<G,E7C?6,.H"%==7;A*.<4C:1B5D1/3717#$B*1'!E:$"$CF&'1#*(->+>.(%7*C+3CE?1!';50A4&>(+H>@31@4G@,=(%C=F/9:A63C8B(1!1E"6789@/D2!.2196&/@:?>,GG/1E;%<$>=C9$(7E?>;"7'*453?-DA5"36$1
@r9802
GANTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATT
+
$&!$&+$#$*#()('+#$"+&%'+'$+($($!$%&(+#)#'")&*(+*""*&""(()%**!)+"(!+'&!$+%*+*&+'#''
@r9803
CGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCANGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAANGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCG
+
C-EBA83?8@8.1HG8A<%72'<9A<F%&;-:;$4>><3*3G(3/DA)9$B!CC7A1-(/7>0&H;"62D&H<.6?>@941##H2/5D@9D&=1E>7-2<E,*'#,,*)A2-H';,!.$:<ABC2FH%:7@((61$E(-);&A9FC6F/0?";,:68>#>04#%(ABB@92&<H/D989&&3(,-8!672@
@r9804
GGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCT
+
>+$9C2%9+9=#H=-6-HA-D*'#9!;1(A432EE,G,HE":1"#!$'7>C)G=3)<6%&34?@B.5@!6;+C',
@r9805
NNTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTNATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGC
+
!(&G!.3)(>$?H;(F:!AB$(0+?D.=7"C56295&'!<;!128@/9:4>/D)96+C0"B0"08,(E#>1)9;@)7+&-F94&)-D<<F$(;@6D5#$/#H-D7E%7'(!'/9@//?4F"'E+?5*)441D@1/F@1=9#A*;;F?H3%0##E*H4,&11--A8#*?5/0#+
@r9806
TGAAGAGAAANAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGNCCCAGCACCTGNT
+
D7@..$B<8H%E9/6.?C%A;1/>%2@952:$#9G*G%9=2!'"<(EE(,%B80(A6-5;
@r9807
GCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAACTTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTC
+
+'&%'!))+""'#%")"!"$$!*&#)('"!)#)&%'"#()"$(&"!)$"+)&'%%+%#)+(###'''%%%*)#"!($()##+'&)'''!'(
@r9808
ATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGTTGTGTTGCGCTGTAATTCTTCT
+
/*B@.0"HA/%A='6!;#48#E:29,+0@G*;$:B?&"83,'3BH#!63A>4.E6H8,@G7$292>F-33
@r9809
AAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCATTCGGGTCGCCCCATCTCACGCG
+
6DH'/4#A1-?+@C(H7!9-:9"*=1H1"+39A77<)G;B321D'')&#A!:32#CBH>1:,!3H%+%43$&B%)>.@='%.=C-<E+"23-/>$&;&
@r9810
AGGCGCAACAGTAACCAGCATAAATCAGGCCGCNGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACTGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGNTGAGCACGAACCTGGTTTTTAAGGAGTGTCGCNAGAGTGCCGCGA
+
5G=/43-=)=HC#0!48?8>8?9A6$1=!&2F5F38!;1&G%9A(@'&<8?150G>!>A#?$.C@CA6>$)<=D;4%D#+FA$->60-0;40@B5EE,&F:H=>3@8?,!01H1$B3A<GG6HH*/A*'?=%,5;-E:@*)<$A!5F'4,?>)0B/(.>H)B$<04920@:$1.(9
@r9811
TGCATTTCTCCTNCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGNGATAG
+
?:1G13964H:5&9!"F&3G.G!+@2&9A7D!8-,:;,-D2;CA)7E%/"$-4H#D!8?@:'+H3@C.%A?#3)D7-2"01'='?3$0F
@r9812
ATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGC
+
..9?=28<183.;62989'B347:!'4$;;0;4#,;"=H98+=*
@r9813
TTNATGTTCATGGATATTTTTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTG
+
($#%)&+"(+))*$%($*#"*'%$"('!*+)**"&'''()%%(&#"$%&"*#%((*)&'"+)')%')"*
@r9814
GAGCACNTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCAC
+
B&CG@#0!&D'14@8=1C=**HG5(3>(#;1("0AC$:4$##9CH#3?
@r9815
GANNNGTGGNNGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGNTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCNGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCAGAAAGAGC
+
(($'!&)##"#)&!&'"*("&+)*!*!!)'&&)(""!%&*('*+)++$*!"#''%)$"+'++*""!*++"$%%)"+''+&%&)))!+'%#(%(!&%$'&'('(%&+#+)+&"+$"!!*!$)(&*"!&*)#%'$)!#%((#!'"+#+#)&*%!"""%!($+$)+!%+)'"%+!"#&+*(!'(*)$*)&+!$%%)%+(*+!"'*"#$!#+#))#&*%
@r9816
AACGCCACGACTCGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGG
+
2E?88D::E3H'4F<?H1A'=B>,*H@76!E93-5=G3"D@,%601$06),<4+<81A"%<C9<8@'
@r9817
NCNACNTNNGGNCACACGTCGCCTTAAAGCAATTTATGAAAAAAANAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGANGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGNAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCA
+
"(!")"(#*$$#("+!(+*'*&+&&'$!*#(((!#$*#$%#$('**"$)&#)%'*#$%+)+$"%&"&%'"!#&$#((%*!))'%!+$(%("(%#!(!*&"+)*"!(&'!"*'$$#*!!$('#$(#$**'(!)&$!("!#)!+%+%&+*%$('+%&(**'+!)"*$$!*$+!''%%'!+(+)#'''%!$('+%))#((#"!%%(+%'!)#(+)&%#
@r9818
ATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGA
+
(/2#+2>/;9;'F+@?6.,;*D)*%.0<G1A23!4,.G.!(=0+
@r9819
AAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAA
+
E$H:,.79G.=;5&8E@(5$)!6:06-1HCF,6'!<**-66@:;,?D>0-2:$>73.=6'4D?@8+/47(?
@r9820
ATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGC
+
A;.";+/#76>$7.*#<.D7B<B9C+4*7.F>.-)99);*E@)@>1(D)+,B2,E*G$$H37?8.@!65,H%"8
@r9821
TTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCG
+
8*A'.!#*$-($6'80=14'$5"1,$12;")8&#..D.#52:@:&=&00-E3=G7;.-7+>G/'!:;>(**-:<%)<7//%B/57A!1E0B
@r9822
GNACANGAAGCTCGTTGAGNTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCC
+
$%%"***(%)$(($''((%(+)!$+(%!#!*#"()&&+)$#(($!!&!!!("!"&)&*
@r9823
CANTGACTGGTCGCNGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGA
+
$#$B"26D("'480@@A,"C2.4BD6)C#73,5&CH#H6A5-?-5=H8F,890%1*/9=/E<.$"A"-:?.D.,@)02*'+'=*6$A=#48B-H7=6F77*<//)8@H<?45,C5@47'?*(.?/,-$)=-1*1-%D86A<'#0=D0B'5A-7$B!#B=2CGCC.D-,=*%8H8?A4<#$?!D&?2?,G<A3<9)@H/
@r9824
ATTTCGNATAACAGAAAGGCCGGGGAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACNCGGATATTATCGTGAGGATGCGTCATCGCCNTTGCTCGC
+
E+B7D>1B1.0(!>7<B*4.H#-F5<6>38B9A>:<!<H0>0A((!12605107,$,188=8,"!"E5D51+-)F,F;A#*@F'"34(G%E9&28<9$0=>,A@4<G>$&,88-,
@r9825
TTTATAAGGGGAGCGGTGACCCTTACCCGAATCCGCNTTCAGACGTTGACTGGNCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAG
+
0FG'5<<-D&7)>3,F828(3+8C%9B9E=(6B66"(+B/--9&6"H"!C=!;9"?!?DH%63,=$*3"#H-8@5EH1.@*)D6860#5&A.CA"HD"4%,7?HB*,0-+#!E'H<E@
@r9826
NCNNGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATA
+
")#%+"!*)**)(!#$*'*#%%&!!(((&")+&")%(*#")'*%%"+$!%+#"($%&+#*"(+!&(#+"*"%$"*$&*''
@r9827
CAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTCCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCNTCCACAGAGAAACAAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACT
+
HC+75EE)B.@H$'?"?=8A9.!$(@=9;?#D%!7*+1<(33&.+6);C@8EE6;=:3,D8H>C035#3?'@FBFD:5FA:B8076DH@&.%H*@<%%</D!@0#6G<%:'8B7,4:D-?/!*C@*&-<@'=FG#H%!@2;:C#H?G4C"/H<4F845D93G%$'>?:6%:><3@+6;;+%1<3E8E?,>#B
@r9828
ATGACCCGACGGTACAGTTTGNGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGAC
+
,/,C(:0C&%.4:#3&'90D$B"'D)G=3'B@4/AB/4:4<CEF,1:/$";2,>&0$D$3
@r9829
AAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGTTAACGAT
+
>810>+B80@E21-/@.&B00BAE=-G?&<!E;0-BB52,;(?0-67;&43960+;,@6/F2550F!/F&'2F-H+>%/(#A$=;@:9*F;<FC-GC5>D>8FF+2@/
@r9830
GAAAACACCGTCAAAAATATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATACTCTGCTGGCCGGAACTAATGAATTTATTGGT
+
%E,7#.C#<E#8?+8<!@A98#=:.,9E7B12;8-'8"'<5"1<4H=-*23+E)-F@F38$;C,D%7/@G,*<2:##&<6*=039%H(40>;".4'>-6=19#(:>6+(,!E3@(5??/3C-?5.-AA
@r9831
TCGAGTGCCTCATTGCGTCGCTTTATGCTGTCCCACAGTAT
+
.@D,-,/D+#@2;>>/G9B3H4@@"A7$;27:52-/G2,>(
@r9832
GAGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGT
+
7-#-&E-:+/!C?0:-'==<5*)(4B56#4);,:;E5>F,HH>8$-!>+..04)>H;C8/#)-.%9?(B2H5#5+/8$F/
@r9833
GGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCNACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATA
+
?#*=>DE)5<#;G@G0;E,>;!A;2"6,7=6$'7A+'=@;#,<AE=)%!$H1?=>529/AEG0@7E&B(FB3!1C8&95D'DF9B)0570H2&C(0:'@CF&3/7.
@r9834
NTCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGNACG
+
$CAF<=C<A1E>-(-32--!)+&"C3EF@'"/&<H6C7"B"8"6H$/116/>54262,EG2*-/A01D/?FA+<HBA:B%+(-C&E,GB##=C#!325<)(3'"'??E8)'&;D)H!$71@065
@r9835
ACTGTNTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGG
+
%F0&/F&#>=7!F'>()7&"%)FC3.,(,"D9DA(0<+HBA@5*%30.4C8+D6#96!>&B>3G$'=1;#DG!(;4)+$$BD5!>2$",4C4B$';#
@r9836
CTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTA
+
(G5G",A'+A,>"<2&C.<)7&8)BAC&?($>57F;,/>5"15:45/<&88/A22A$<+@&4?!9-@225C-?!!=0(?D?'!H
@r9837
TCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGG
+
.C-#9;B/<&#1D7A*6>%46$C2F3DDF::'=)456(/G!!&<A=$)&?G1:(6A:='H
@r9838
TGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTGG
+
<(*A",'EBF$A0%D3)?C?8+6$G:7<A%H$6'1#?&:,HB:@>,421"8H#1=6!?<7D*+&0(<::05AH#H%0"=9.13<>9'C*9*H
@r9839
CAGTCGGATAAATTCGCACAGCAGCAACGGGCAAACCGGGCCG
+
.),.!<@%A3(';(G:B)2+4<%@'&;4#F*62DF&CA-8&/1
@r9840
GATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTAT
+
;C=55G,D52$C&;A'7$%$3'B&9(;!?"!$&.'&.>"DAG;A5?&%.8B=C0)<&'>%'%)5
@r9841
CTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGNATCCAGNGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGNAAACATCTGGCGGGTTGCGTNTATCCGGGACTGCAGTGTCTC
+
5H%D"5B:3/4>@6!/5A!E=F!)$@G0?0@#*;*04/8),3<-<$334:@&%>;69/#%!*D&%2988E)!/<7-H9<+0-#380*4A76(2?<2)FGEC-"H!4$0),"+?);93(-;/+7A&%*3)+1$.'1H!*<6=E-(GB:/G>D04%@G0-2C+(A!2/6!5F-@B!1*/=7A/&'82"4(3:0G,:7>E@#79/("+C4?*=>%31=A(2(@?6F<#*=F5;-=B3(?5++:
@r9842
TAGTCCAGCNATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAAT
+
+!!!'$&#+*#'+)'&!)$'+(+'$!(""#&!'*!&%#%&#%'#%$+&*%)%&#+))(&+!*"'"!+
@r9843
GGNATGCCACAGCGTCCTGACTNTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACA
+
%#!)33DE<&A>"/A:E!G#38/:DHHG;E7-6%(6$>/B:5E*%+.9A-D"E-?:96.'8*((GD/9"$**.'A:!;HH/G6F,)1%&&+/)06"E+-"&4?.H<&15(!$H+5C:F%+:*C@6"A63-D@*G
@r9844
GACGGCGCTGGCAGGGCTTTCCACGGCGAAGAATAAATTACCGTATTTTGCG
+
H%D;B6>76F(999$39<"3$3@?E5B;!5@G,.G?.97.:/>1$>$4E283
@r9845
TCGTCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACG
+
%)%!('+#!#$(%*"&"'''+(#(+$"&)$"!")*#+$%'%*")$
@r9846
TACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGG
+
>0$6!@,D:(9A<#%19BC%!&/8.).79A?#!E07;0,8;%6):D
@r9847
GGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAANCTGATTACTAAACACAGTAGC
+
729'8)/DD?<>/&*B72?@C..-06?8#5%DCB,0HDE-;@%A';0531<G!><F.'E2*F4H?<,H!54F1(G=?&<,13"91/
@r9848
NGGGTTACTATAAGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCNTGCAGTAGAAAAAAAAAAG
+
-G,%$$%-E:5)??F(/E.A5699B";?*'(#"7@+)@3G;!-0<@04!@+885@=6+32B6G5>88#-$=
@r9849
ACTACAGACTCTNGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATA
+
'7$7%&=@C$)D;-)A0*4=<#!3D-E=C/2,H2!B@&71'#:2.';2386.&&AF25,C,2.H>#9;&8'*6G-7ECC6*0($?7!C!DD(,G'$0098=B6B2H#5(75-*D+80<
@r9850
GAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGAANGGATTCCAAAGTTCTCAAT
+
?E+BB,6?).%*<854'16"),(D0F)7C9GD'?C?&7=G.58(7D$(=/"#BC@C>95#<?1!&>*8D))6=BF1!B2:.<247EFD>E*D72H=.3@;0H))>1<3*+.CE%00,
@r9851
GCGCATAAGCAAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCA
+
*%4->-C42C2<5@'B#*:D)C.?=/.-;9D(1A4DF0#+.5:11</GE:/)')(@
@r9852
NCAGGAATATACCCGCCTCTTTCAGTAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAAAATNACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTA
+
&./4+-&!#!@=0<).'>4!D+4F?#!C9G";/0-A(%:0$?'D>;E",/;!E->+'+""B93=G+)H-,2'(!)!7!E&.+B,"..H>2B=1H&H.-41<8B)6%H"H?<E1/4.-2%E8+A@>;8'@&6!(<2?&09#B5*,F&.2"1
@r9853
GGTATGCATGCTGGGTGTGGGGAAGTCGTGNAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATC
+
4)&14@#:2,5GB@F-65D/*H<&.8<1C0*2!</4>!8H%$.>!F2';?-68B1=+/()F$%F,)13@2+'
@r9854
TCATTAAACCACGCCAGCAGCGCCTNCTGCCCCTGCTCTCCGGGNATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCGGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGNTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTC
+
=*8?*5'-B#.5B3(>,9>-*ABGB+1?-#C74D"3;.+=DE'1BG5@#3G6.0"0%0"<;45??,>@7(/?C#G'D;8@3?73H+7F@@0@"BGG%$6''!/,",A'021/0"3)7=@8#1C84A<9E(("E!!<5(H0>?$CAA5:'%7/8753&"47=:/#&A=!=!0)$AF#7!5"&78E.A7$>725%>!0@>F@3B@8"$C>-E6$B$*<:4-1#@"G7"88!$-!-9B"6'"=.(B$:&1&(:>E(E!.<:F!%?A$(?'%!C0:3;.3*1(+',=*A$0>1)'>HA&!/<!762<0;@+))'$96)
@r9855
GTCCGGCACTGACCGCAACTCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCG
+
/(,=&B"H7FB95A?,&!5%2.'0+:B>F$9@%-E6D?#@3D!4+595&(H.B1;%B+2C(-'(20@<D!+(4>"6>(/H#?$'#)BA.G
@r9856
ATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAG
+
+%1@%=0C/35D&&EH".E(39A2A4;CB!>H4'>;+&CG10=E72-G
@r9857
GCNCNNNNCTGCCTTTTAAAACATTCCAGTATATCACTTCTCATTCTTGCGTAGCAAAATGCCATCTCTTCAGCTATCTCAGCATTGGTGACC
+
)!!**$!"+#)!%"%&(($))"##%+#!$$#)$*$"(%*$#)'!'*'!"*$&$'%+$$&%$"'+#*+!&*'#)!'%$'&*$+&%'")$()!(+
@r9858
NGCTCAGAAAAGCAAGCATCTACTCCNATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATCATAATCAAAAAAGTATTTCATGGAAAATAGTNAGAGAAAACGAAGAANAAAAACCGACTTT
+
!*&)'+(%)#")&!('#(+%%'*'+%(!#(""'!%)%"#%$*$'*"++'!!*"(')""#%+#"*#&#'#+&!!))#&$)!$"#$##($+)$)!*#*"%$()!"$*%$!(+)'$"%+"!(+#%&#)$'+"#+)'&$)%&)($!)%$&&+#!")')
@r9859
TGACCGTGGCCCTTTNCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGGTGACGCCGACTGCGATATCGCGGATGAAGCAA
+
@;=G7/4;GH1:!G5*G"C7??-@,!@%E33GA#F3'0D(1"E5)%9(ACH;'+.)B.:DB59='$":+=E4'5<4%!=G7F>,846%1%"F6?'+%/<,@-"8E%
@r9860
GTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCT
+
B$6G&(G72?.,$D(<,3)6<,A05)%"2=%1@3E+(3@E21
@r9861
ATTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAATGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGA
+
"".E3C=(E30"*?4!1!/)&"?!1("3D=-;=$@C8*1<3,&@#:E03F9273D?4)#E'2$74'0'(G4#F/9F:2C6,)9+'4->F,:<87H1B99.%,B#?#F6;+.F5&/F>?HF'>G*#
@r9862
ATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCATTTCTGCAAGCTTGGCTG
+
C=&)#82D4D&=9'.!=-4&/?&<&@;3;G'H9@@*)*7!8+'BB'5.&3H0GD*D,'<($>$91-8B1/C*E?)9@!14(?;H1
@r9863
AGNCNNTNNATTTTTNNCCNGNCTGNTGNGGTNCGGCAGNTTANCNGTNGAGNCACGCTGACCATCGGTGAG
+
#$$'"#&!'!#!$!*"'%*#*&&&%%)$!&"!"(&&&#)'$"#$#()')*&*"+'#*&+&%$#*#*("!#$"
@r9864
TTCCACATGAAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGNGTGC
+
,(%=1,$51E.32=!<68$/1=-87;0(;:@A69.@3(;F*!+#25G@C!8"+E>*2'3%F$(F.:5E$;;2!'3A,
@r9865
GCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGT
+
)*2BHA'C:!!*AH<'8G;7+9:89-GF%$(9&"48,=##0,124:-'E"1#F@1=6=&<CHG@65'0B8C%6<D6#3'&'FFH+8$+G.D35)'736'8E--99%$G-%+:-/=A80@D:3G-1*6=
@r9866
ACNGNANTNTCANNAGNNNTGTAGGNTNCACANNNNNANANNGCTNNANNGTNNCNGTTNNGNGGCNANCGNACNTNCCNANNNGACNTNNNANGTNCNGGGATTNANNNNNNNACANNGNGGNNTCANANTTAANNNCGTTNNANGAAANCTNCGNNNNNTCNNN
+
!#!$"!"!#""#!!!!"!"#!#"!!$$!##"$"!!!##!$!###$!""#!!$!##$#!$#"$"!"!!#!#$!!#!""##"!"#$$$"$#!!!$#$!!$$#"""""!!#!$$"!#!$"#!$$!#!"!$##!#!$#$""$"$#!!#!"###$$"""$$!#!!!$"##!
@r9867
AACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTNAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATANGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTT
+
0)01:"/A*DG/1%.GD6)3-ED8/7@F2'B:)$:.62!!HHG?7!-.$*H$97%:+>(+7><6>1=F':*H=8!=7!=H'<"4.%=H1%22%3EB+#F35!531(FB##BE9!F6$;"(7!$()+,%."&%;1@"$8?)59?0>8&0&-53G#%2+(4F3:+(AE.+9661?B#1-4=D7>@4=:=%'"#)&F9C5G3FF:5FC%32%;<HG4$*":B,%!?@?2-4%.+
@r9868
GGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGT
+
7-%8">5H;<8ED8%-:#"B7B(E=+2;H$&BB(9C1/C6,70H$"0*)G/4:!#&5.=:$"C/(A22$83,04B!FF=.;:3A,'-350$.CC(B+,@!?-+2@'=C*#HEE3+:?,0>1F,G((:E=D%!%:H/,,%:??@8>!>.@8#
@r9869
AATGGCNACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTTTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATNTTTTCACTTAATAGTATTGGTTGNGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAAGGTGCTCAAATCTTCATACAGAAAGATTTGAATTAATATTTTAACCCCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAANGAA
+
:5=80%*7,'<>FD?":'H*;0F-%A8A)(!%B.;#=1C=A7!%+$A917H.!,<48,#HC2#*4#46<C!'D4,33@1-+>6.<*C77F32?6=)06<3E*>9C!"7<.G$88(9'C3!0@),,9(8=//!G!'B!E*6+BG$3*$*30:7"?%;D7(9C=,0E?=<58E153C,-6*5;')&6@@4*F>?"0'-1%B&="E?EEB:#@,-*3"&D'!EG!;-E85@B,9G;'/9B))<-?%4;A92.81.-73'6!4B&1@$;%0DA9<.GH8&",H8+',C)C>>$C2@>$8E"B4H-F/*,/0AF<,D,
@r9870
GATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACC
+
C?CG5H0/)2),-+5;%.0/")B:5=2.<<G5@)'0$+')9:?$/0:'#=DB7F6HB>"F'<@($?*C"28H"#>3>></%93("D@%6E&044(1>2H:G%6BH4%1.=
@r9871
GCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTG
+
$(3#2,8&6B>0>F1@;!550/87-2GEF<"?,687/97FC&'
@r9872
GTGCAGATAGAGTTGCCCATATCGATGGGCAACTCAAGCAATTATTGTGAGCNATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGA
+
=4GF%7C'G;/C9!DDD!52%=E*!@A/)??)G17,)8-A0@<-&44*7*2+&G(--GD%&=E%,;D,<#,5F?4&56E*9%B8!:?)40),0)?18>,3*-7'"AC%%/7-BD1E;8F:5--D8";+7,-&C"%%/!-523>.7+##&.G";F%:-7(:-!B7&=@B.=5,,#/$!7.$?-$45=$<=))"9$@"2%#$;,;(?)
@r9873
TTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCNAGT
+
0,4,6<6(D>F(BC2H:<<...A4A27/;+68$1-A(5(5AC<17>
@r9874
TTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTACAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTG
+
)*4@.A&-@.-">&E+F""&H2<?'.!H9.4C+.!F*-5EB"'+.?2&:!8"0."=-;-58+3#-E@1'&./D#*(#E,5D1"?(-"C"">/*'4;0/F+%1"5<F@?9FB!#$-F&&$*?=@D/$.;>7B>3FF29F%23=512=FD5,DH/&;;00=+(+0>9"#G35?;C252A*F;';#D67G+@/8-:0,CH0;%F#4"!279;3:/42+A$&E-)$2A4%<H$EFC69&&@)!:(;4E:'.#C!(%HF/(D(G0C1<!$7/(@-FA:88G6%A6=%*04!&GF<=304!$9,"(8=2AC-8-@D?BF<5HE-'FF(!&:'#0((;!:?!:H<%3!%>(F@;4E!(A20>4=;A*D-6C)B*"*15963(.),#94)%8
@r9875
TCACTGTTGAAAACAGCCACAAAGCTAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAAAAAATTCATTAGTTCCGGCCGGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAAT
+
+"$!%%!!")()'"'%%*$**!$&$&&*+!*)'##"++%)!##)!%!!%#+&&+"+(!#$+"$(!!#+#"))$%!%''*)+(("$#+"%"*)!!+%%%*)*$"'*)%))'%'$"%$&'"%!%'&$#%%+%"&*++)'&$&&""(!'"'"$$&!#&#(+!'"+'!*$%#&$(%*$#*)%!%#!*'$(##!%'$$)"!)*+!*('')(($"!+&!)
@r9876
TTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTAAANTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACTCGGCAGTTAACATTCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGNTACTTAGATATTGGCCTTGG
+
+==7(8:"-E3<%#.>=CC;41C:>=-3?3A)!H71>">8+0&(6.<)0;1=3,G.**@%C,(>+35<B*@C1*'E0#)B%-D7'1/.?8)-*7'3('&,&D::D&(75"7/&0&&)#)G++!?@7+(E+<5F<1-08-51,:A?<<9:9%;05'>70E;;A"89.5(CE(123B>1$,=($'.H20='?&$C+B/-.C.!<(:.:24?"2@:?,HCA<.C'@407C)5"6C/%/4$<
@r9877
CGCTGCTGGCTNATTTTCTCATTTGCTCCGGCATGCTTCTC
+
=,C"6)39(8%8GG>B4>8/>HEBAC",F&&.E:"=F62#C
@r9878
GATCAGTATTTCCCGCCTGGCAGCTGGATCTNAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGNATGGTGCAGCANCCAACAAGAAAACACTGGCAGATT
+
!,>-E;A%%>.,A*,'AC31E=#:.=-1F!$E?5!'"G=(4BC5;'>B(=1GHH==%;0-%AF##;G,@4D/%*0+1HE41A03.45=F=;<+'$@++4
@r9879
AAGGTATTGGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGT
+
276)*13?53G<*$992*'+:5-?3;$:)*33.,G)F1%/;B)$//G:9=#1A*-H7?+/0
@r9880
AGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCNTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGAC
+
)(F<01?0E;?ACBBG@6!&$?%?-H,-".164>"0?D:!1&"1B*#=2"1!@:.>1$#B0"G/;75)!H.63:6B6%;,?4-@*?E!'</&H?
@r9881
TAATTCATAGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTG
+
@29,4&-E(3@/2)G+-;8,!-885=DB6*99;5-.&//GCAF"3>/!4$%H@*">!$3@
@r9882
ATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCNATA
+
CG$;.B>883+>-0=58@BH?8A4#E'2"0&15>)+#@C3E7933";'&@D+
@r9883
CTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATAGAGTANTCTTTTAATTTAGGTTA
+
FHB3.<@($*B<?D464"G9&2(023@E8!7$4(4&5%0H16902B3//D?B>D@A/.4$89")9>-C!A*D,?86@.7:@BH(#5B$>E#&>G450@.13'%GF0!%?EH*0!<5105$92ECC*<59?+C>)6<9+..?0$,">30+<8%)#4%0E39:6HHAG51&84<!=@F510*5/#39H=&$*>@+80*F!7"/6%?-D4**1E&?,*>+4,E8@20--F4="4H<>3GE5>D+C,C2C<0,F"=*CH(+:B;9<0?1'H&F&,C-G2C@CE,5C/49*F97)GD8:',,#
@r9884
NNTCATNANGGTNTTTANGANGATACAGGTATAGNTATANGGNGGGCATACNNANATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTAC
+
%")*(##(!&$)'*%''"&&&%"#!"#%$)'*'$!***'!"#"#)*#&($*!!#"'&%'+$&$"++&*&+#"$&*++)*"$)))!!"+(")+'')&*$+*+($(('"#"('+!"$+))!!#($*%+"*""''+)$)"$")(!+&$(%!"%&'#*')"+"&&*#%#%)*#$('!"((+%#
@r9885
GCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGG
+
1048B:2:"B,5?$E5=/E3HD)!,G+9.+@3!A9<G'H+.+B58$%-+=-H&02)&$?C@A*'0?;
@r9886
ANNCNTNTTCGGGATTTTTTATATCTGNANAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTNAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAANTGCGTACAGGCGTCATCGCCGCCNAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGNCCTTTTACACATGACCTTCCTGAA
+
#%!$"&+(#$$')("'&&!)#$$$)*%((*#!%$)"'("#)$%$)"$"(%!#'#&&*&%%%*'%#*&('"'&'(&%"))"#+'%+)%+("*#")*)((#&(&!%$&*!&!"$"(*&)"!)((%#$%)'!'%(+%&$#*)#%!+#+$('*+!#"("&!'+&$"$!%)"!!##*"&&!*$"#$)"$**&'$*)(&'#"#(+##'+"(*"*$!)"$$&&$%$)+((+"!*"%$&%*"'+&('(#(#&$))%%!(%*#%#&*'))('&
@r9887
NGNNGANNNTTGNTGNCTNCNTTTGTTCATTCCACGGACANAAACAGAGAAAGGAAACCACANAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTT
+
(%*#(%%&("%'#(*)%*!)"+%#"+*&*&#+)$)!"#!)')')""")%$+"($*'(!!%*'()!)!'#$*!)+)*&&)()"(%"#)%))"(!&"+%))"&)(!"""
@r9888
ACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCNGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACGGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAAC
+
AB795H:EA0;B@0(A,*F-8E!$-*4&9E/*)<6=B2!8$!)6B76>;<.+G@9C:A"FH@3>/,916534*-!CB4/*555C(?D?.(.CE*E"C1);6CH<+<,>)107';41*<%CC=",=/;"68#5)44D3"7:(F5%'HC48=!:0C!G/9!GF+H096+C360>2+
@r9889
NATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAA
+
0F,=<:&>H,-A@?/7F3%+,%#D#7"2;.,0?B&=#D"214G2)"&,?H-;01F/+1'.@6)9
@r9890
CGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCT
+
FC3C%A+@.);#9/-0%A8>5@0:8/,2C!4A5?(?,@1=!10A-DH;*5$,05DD%@24-;?7>=:5)(#=:69!6+H$:H#1(%D&5.8*9?F0*4*E6==$6D6+:4>C-4'>&/;1%:1D%//&C,%)('2+7-D=*A+*
@r9891
TCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCNAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCANAACGTGATAGCAAAACCCCGCTCCGGA
+
$8@52D+%->.D)8E"<.!FH+;FG9;&%H41E04G5%1<"1B+"/4$BCF257<D965519''.="FB*D&CC/><A.&*:'"H54';7B?7-,-C3$05C>1FE8!6>+0:H4942A28;%(4?&85?+C'D:?><C<@3*(0B55.(E%F:?556!286;:8HE%-<B',0+/5!.F$AD&9,
@r9892
GTTTCGCGTTCTTTACTTCGTCNTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGNGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCG
+
'+#&'$&+)%&"%%**$$%)%+%($')#)&+)#!%'&(!($)!(#)*((+((*'$*&#$%$'*"$#'$%%)!&($#''(%((#'"%+*(!*$%&#!&#(%")&'&$!"%%*$+&&)%%((+%*+(++
@r9893
AATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTG
+
7=?4?6;@1<-(H8%-0D@;.,B@)!#);8A6+G:!GB:#-,;2+H"$!)
@r9894
AATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCNGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTANGACCGGCTGCACGGCACTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGNACTTCTTT
+
7)'5:D%9';6*;9?*'"?+G%!:9=5CHA+<2.A5H('&"=F-."2H/09G&==GG<F!'&1:0>=7D;"8>=+$!+79=%=/5FG$:<1A2F#9*$93C1C!/#*7=A+G&0A3/5$@3@;%2";*&/!!/>7.0.H,8"(H%08D,.?*4+74,C5,0()@),2%9:F573.&D#H',)@:@:+<<8E:%C&12A7*=ED5G%493EF(?$GF#+*@&*#(<0D>41F6&,<,3-F5F
@r9895
GATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTA
+
H;67G(0%,E).(D)76<,4!$&='?7C=;<C-,1.H'BFC+$!13@HD>3<00:'83/><7#$D&B?E(?A"GB57E12*!#$BE<
@r9896
CTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTA
+
:$.9++G:H?9.(D5>*F8A6?/)$%.@@7!.E<-4$&1*(-:0+B='*
@r9897
TTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCGAACCCTGCAATGGCATATTGCATGGTGTGC
+
1/7;)2<A?E9.>H1"H501G1%5+H?'6A/<C'0%B#4<C2830"E!1DF@$+,-%4!>#50>!=7FH
@r9898
GGCCGTTACNCCACCAGTCATCNTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGT
+
+91@);D=$)1"/7=)6>9G046/4/<7)'EF;2+$$5?-E*?,2+E+6/?:+$D;4=693.)43E66F$>.;7<%@-$094-HC3$+,0
@r9899
CTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACAT
+
<*95#&BD0!$%>@+.)!<45$6(+)2*-'+*,*+(F$8):)"7'!9&&C>*1/0*)8A13<9
@r9900
TCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCC
+
9"=@*2E)8D/A3A10G;8::C7053:'$B@7-&!C6!GD===:$?>?25H%E>30,@&''@(4'G2&F($-'37-2FA$
@r9901
TATTGATATTTATATCATTTTACGTTTCTCGTTAAGCTTTTTTATACT
+
=&E5?+B#6;>F59.4A)#*%A4'<BCE,#/*DB2!9?2$E-!%D)34
@r9902
CATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTT
+
9=6H?FG.;/=%FFE7&@-:;3#C&/.8",9#9/3=1&5$.$0+A)AD5#$&=*EH3+2!4#-H@3C)'-&!A3)1/8A7-,F,7'179B)!?B3:F)!
@r9903
ATCTGATTCCAGGCTTTGGNTTTAGCCGCTTCGGTTCATCAGNTCTGATGCCATTCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATNACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATANCGATAAATGGCTTCAGATCNGGCAT
+
D8+E=1@//?3%=0+8!*>)G'63"<:E>%CE<:7?<!&H@#A.H*C=&,#5!0(1C+(%;D:HA%0#>D@8-5G12-B2!448/G!0(G=@2=)(30$'3(GB(B4*<:1>4/GDC"0+,G=(3!-"43+$GED48<1B/.HC9+2?H72%1/C.;;?*,84G5'=$?2=C194!#7(<G;&86>65<%C<#-;=*'"3B&
@r9904
TNGANNNCNCCTAATTCAANGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATAAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAA
+
#$!'*$")$&*%(("#&)(##$+&+%*(&#*'#%!!)+!('&+!"("+%+&*$$$&()"$'!$+$*%$!""*%!#")!%(("*&!#'+)'"("$!(&"*$")'%&)++&(!+
@r9905
GCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGC
+
D<:"A2)GD'$H@-C0=0+F&A,$/8@(>3++.G.BB2+55$?=H:*"A1-4264"H:;1H2C>0:3+8@4?*>;&$$
@r9906
NNNCNTNTNGTCGGACTANNANCTCNNGTTCNATTCNNANCNTNGGAGCCGNA
+
!""###""$!#"##$"$$!!"#$""!"$"!#!##$#!#!"#!#!##""###$$
@r9907
CTGTCGCCTTCGTGGATGCCGTTGACGCACACCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCNGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGA
+
=4E#6$9C+'0$1@7;2*0*$5/?&3%=)?HF>=1=6+!@CB)FH%@@97D>,BF;AB$%>G%3'>):>A+/)6-,71+,/5.@$946H'.?$6,!"H=&>DB$1D7@0)+D<G.D02#!0C,H*/EF#%49:$;@/7!0;!?>%94>5<D+0-F'7.*>/:E(9->(G,0+!&(5C0;(.2G00!%GD/<H-9$3>1A'GH*.7./5%A,&E>EF,5%<4)00.2>/<=8B)"!8C5D8;G-#.?7893E/#C7+22)B6/?6@=BE%-9/6+,6@*;AD0?@6B.D)>CH945?3?DD3AD#($#/G=*>+-99BB+<+E)=-
@r9908
GCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCGGGAAATGATGGTGGCGAAAGCAGAAGCAGAT
+
+#&(!$#)!((+(%$$$++&#(%*)()')%+!'!"*"'#("""$"%)*"(+"!&#(#+!"!+')+%&"*&%)'"((+&%$%&"'&'+)'*+(!)*'('"+)%)#(##($!&"&#*''
@r9909
ATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGGGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCCATCAGCCAGCTTTCCT
+
9"3,0'4#%?(/%,6+#D1"A3596,06EF?@6<@(,1C-#!C;8;96+9B4G:<."08EEA/,.EG@1-:@H(5HH+!2F901B*E/B150&=4C58*%@45=H'.B2:=ED)):);*5'##B-7H*GG)&;&)8737@82%66#%")#D<<)G((?<&3BH4!9)7$A$"+;>H"A<0/-C4(-*CEAB7
@r9910
TTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTANGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGC
+
&+$'(!#")(!$(#'*#*!$$'+(#&+*"'&*!%$!(%*''%+%#(#$($#$"%###''+%'"!++")%#!*%'%#&*+&+$#*))*!%"&*'
@r9911
AATATGGCGGCGATGCTGACCGGCAGTGAGCAGCACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTCAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCAT
+
#E7-*A=B?CH9%2@*"43F,06>.F<-DA/).&&(76>87'?#"H18*=*"$)G'H4H#*BF.B7G&173!0.F*8:E'5C4&!2D+1*???$/!1<B6>,?7-$D!)!$)57$DFA$(1#17B?E1EF:
@r9912
GCGATGCCAGTGCATCAGATGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCNCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGNGGC
+
A-+"""@G<F05(/G4G8<E3=;9!'&8E$/7-'G6,?!,G&'%#;.4+11H*-"6.HF!6"DE*=$7#5'.EC*90A19*D'%#(BH<+9$H$(9E$,1!0F$,#CB83#@?+%D*%!"2$5,7F*A;<>=<B,=C1<CE@>G9>C%%#'0D*?3,00(@-)>D5GB3'!63-8
@r9913
ATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGAT
+
FH??F/9C;&7?62/722'!-45097=7?6H&566A+F:)8E()60!,8A-
@r9914
TGACTAACGCGCTTGCGGGTAATCAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTT
+
18F78379BBA.3"=;'*@!3-2>1H*G$F*,:+/6.H<)?@B+*45-;2.50C-F9=73H$F5=6)$B"1(-10''-6F.$$E3""9&D=
@r9915
TCCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTANCGCTAAAGCACTGGCCTGGGGAAAACAGCANGAGAACGACGCCAGAACCCTGTTNGAATTCACTTCCGGCGT
+
09HA?!;HCD$*5'/&6%)>C;?4:%A<-5/1E7)"?(!4'*)?<+'06'DG',-%B)"?H+5&/6A$%0(F>6(.=#.!@816<B*CFH15!.+1E"&*HA$#4>0B
@r9916
TCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTNCCAGCGANGGACGGCGANAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCNCNTTATGGGGATCCTCAACTGTGAGGAGGCTC
+
1&EH#"5A6:?7H48471D8(74(#D$,:6>G!='3+:@+8?(7#+,H&D-6#6,B'3.90>5723BH<-%,1EB*3(546;3A+62$@'63.DD8+53,>C#!$G3&C8/G;B#+D>>@1"*'=+*&E/*E/2+(#A,+D=B.14%+C#?<D(??A=2>2/,@G(/+)F94>
@r9917
GCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCT
+
E-,(;<FD79F'(B(C1(3C$HA&-D,B<;/;F)&3$F31%B2H-G)5?*10
@r9918
CATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCNATCCAGAC
+
9B%9,%6?97HG3D-#&(.D<2DE!F<G:&&:$!0@H?))E&1A*6:D>").)B!6@A
@r9919
NCATACGNTANTACCTAAGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTGAGACG
+
%*!&%%$!#(!'&+*+$+"*&'%"#'$&)""'+!)(!'%!+)$**)"$$('%(&&&$('#)$(*"!!*!"&'*%"%+'!*$%$&"+$(&#!"$*$!)&*%((%""((('#*$'#)"")$$!)"$(+*'$+"(*#
@r9920
GTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTNGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATGGTTCATCCCGCGTTGCGTGAAGTGCATCAGTATGCANCTTCACCAGTGCCACGACCGT
+
5>"#%94/$F!,171+'HHDE;6E=!A4%.=&G)C2(#A7@?<6H."(.;6+%*@9&&E3)HG)).6.!G46,%!+E1B/"@2)>G,9+8,>9,86F&G2HF4DC:#-<D7GH;'?31'4<%=,?0);@D>)$C;6+%%"F,>("G,C9'/>>5!4!'F%0!:3$*92*/8'G*HC)07H*
@r9921
ATAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCNCCGTCAGTGTCGCATT
+
$HE).&7.D*9<*F+7H0?8C,<*2-E=EB00D=A;,")830*A/8C6+F'H
@r9922
CAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTA
+
=;"C?B%$6F79A;HBA".B5$:.<6!A-:=#E/D-:,'?:'<$!(.!?<:B'HH:GG9-1>2?+>0)E)"E="!CG5"21D0<,G*%'$
@r9923
TAGGAATAAGGTCGATTACTGATAGAANAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAA
+
DFF<29$FD@:-0D$/<C/&+#?&<$DH!8A#!#?*7G(<5<#F64,!!=8'H<.E.6>A(02H41;,,#?*5)B#6!0F1:1,3B+"C5-><$?("CH9@<$!/G#D$&$83'>C'295).>5"#;?GCC10+
@r9924
GTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGTCTCACCACGGGCCACGGCTTCTGCCTCTCTTTCCGGTACTGATGTGATGGCTGCT
+
0779BBH>-!/1++<:</<$&,,4&#%C)>#9+%*%?;6:/9DE1FH3D;#/"::;1*F023A%E3!"2;(5!%$3>33=H(C!<H+5(;&97$'*
@r9925
NTTACTGCTTNGGCCTGTGTCAGTTCTGNCGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGNCGCGTTCCGGCT
+
!++&*%!&#"$#(*)#*+&*($$"'+*!')+%%%++*#!!%*#+#"!""#!#(&(#"#+!+%+)'&('(!)+&#*!+')(+$!$()%*&)$)$+)"!'+%$#%!"!$*'&&+!!$"!%$)+#*&'+&&!"$*%)%*'+'&%)'&+$#(#+$#+)*%+%+(***&)###"
@r9926
AGACTTATCGCCAAAGGCGGTTNAGGTGGTAATGGAGGAAACGAACAGAAAAG
+
&+')*#%+"*')$'!+'&"")#+&#(%!()$*'%*'+#+('#$%'*'()#%#)
@r9927
AAGNNATTGGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCNTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCA
+
$$"%#&+)"#**"!!!&!+"('+$!*)'#!#$(+*#%*$+)*!%)$*!)')$&%%''%"(!)$)'%)#'+*%"(#+#$"(%!&+("('+"*$)"!('%(&($!")((&&"'+%%$")&!*'+
@r9928
GTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCC
+
>?27('-3B<DDD=?12"(+%#-8(F&5+59*%CED>#C!+$AH
@r9929
ATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTNTGGACATAGTTAATC
+
GC454@>54>%F.!-81?6/FDA@00CCAB<8721@<C-*ED"%2!<+-6@28'%,'=->0$$9@<2)
@r9930
GCCACAGACCGCCGTTGAATGGGCGCATGCTAATTACTATC
+
6+)<&15/E4C,+&.>5"A7274-/2C:,)"9&!;-@DFD=
@r9931
AATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTNTTGTGN
+
GD.2.2#:=(>'!.G12."F774$%>52?G'34>H#"';1+=GHB3F>"(63*1)9G;13GGB&C02>86.9F;H)(G7.):%)#(A-G,@3;D9+C+$<0;*;="7G669=2$2.*,291$2+88:*-29*62(-G;,*7&E0/=$#8BE
@r9932
GNNNGNGNGTGCGTATTGCTCACAATNATTGCATGAGTTGCNCATCGATATGGGCAACTNTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCAT
+
"!"*$#(%**+'&+"(#&&!%(#$%%%%!#**$"+!(*"'"&&($&+%+''%&++'"$')(+!&'")'$!(+'"'+'&!)%&(*)''%$!#(!!#"+!)+'+#*##(#+(!&"
@r9933
NAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAG
+
,E0)9#'"$$G*9(9409B@..0?6CF>,C>E.:*!;*9=923@1217E@!$G$8+
@r9934
ATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACNATTGATAAAAATCAATGGTGTGGAC
+
82G33&?1-77;519736>=274)A?"?,%/:%%-99GB=6+;8'-$&&/.HE.A8*(5,<0C#5#G
@r9935
AATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGCATTATTGCCGTAGTGC
+
<A@8-E*H3;,DC=*57!A*(D"F'CD7@("'/B6,16*E0$.B>>8A/C'5-9'*E9$7"A#<$
@r9936
NNCCTGATGTAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACANGGCTGCATCCCCACTTTCACTCGGTGGGTTCCACGACCGC
+
$%?:C,?8#6:B*6@8/.%C9%?=&7B=(B<*%.1<GE@(@*H6)-B:B'!,/0A@6.@6@C05DFDA06:+)E44&C?$:.>.C!9=-GA>C3H';D/D"(CG!0,E(74;6+GH1D*G'93)"#D:F56B$
@r9937
CAAGAAACGCNTCTANNGCCGCANTGCTTNNAAAAATTCTCAAAGTTAGNGTTGAAGAATTTAGCCCTTCAATC
+
()"!$*(($*!'%$))!&*))$)$%'(&($$&(&!++''))''*$"&&*'#''+(")!%"#&"$('%)""+*!*
@r9938
NACTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGAGGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGNTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCC
+
"%+)#&+"(%"!"'*(*'++)%(##$$(&++$$'!&$+))('"*&!'!##%*!*(+'&(!"'#%$%(!%"(('++#**$#)(&%$+%"#*%+*%"''&)*%(+(")%)%)!&+'""$*+)*''#**)&$#&&%%")")"&#%*%(+%!'+(+$'')""*(&"+'&&)"###$%(&()""''+'+"!'*")&"%&$"$&)$$$''+(+**%##'#($)'"*%&&!'"*!%*#)#)#)(
@r9939
GCGTGTTCTGCAGCGTGTCGNGCATCTTCATCTGCTCCATCTCGCTGTAAAACNCATTTGCACCGCGAGTCTGCCCGTCCTCCACGGNTTCAAAAACGTGAATGAACGAGG
+
+(+$&#')!)*%%)!"%)%*('$%*!+!)($'!$+&'((#%#''*+(!$#$+*%&&*(%')("&*(!%)%!$'$$(#+'##'$#"%+*!)&$*#&%!)&&!$)%*()#'#'
@r9940
TGCGCTTCGGTCAGATCAAAANTATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCANTGT
+
F7$%A8A4BG!?B$58H;(3,F4!A7+!(3+B8:340FE.0.@1/?>925?-7:$$G/@=?C8;)-.;3'A+@4A#!49-9%<)@=
@r9941
NNNNCNCNANCANAGNGATTGNCACGGTTNNCCAANGTCTCCGNNNCGANNA
+
#!!!"!##!!#!#"#"$#!$#!#""$#$#"!##$$$""#!$$#!$!##$"!$
@r9942
CTGTTTCNAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCNTTCCCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAG
+
A(/9+<-67=4$A@?=$@&%!,'F>*+1'1,DA&-?.&;A"E4"D2/==HGG>=9-$(34>/<@#1A3<*2:(8!)!F.>G!=)EDB56-/E.30@<;E382:G,%
@r9943
NCATTGTGTATGAACGCTCGAAAAAACATGGGCTGNTCCGGGT
+
'/7$64#:99;-=G%C+?=(8H#.$=$%$;/!$.G,'?>H)G1
@r9944
CTGGNGAAGCATGCCGGAGCAAATGACAAAATCAGCNAGCAGC
+
*'$&'*"+%!*!#'$&%)(%&'"$"++'"(#)'!+"(())"!$
@r9945
NTCAGCCTGTAGNTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTC
+
"+#%*)#+'$#')&(++)!($'#$*%"+$!!%'"")('*$'*'!"#&()!)!(+!!)!"#&(("*(#(&"!+!%#(#'(+("!###&"*#"!(+"!('!$')&!(
@r9946
TGGTCGGGTCAATCCCGCCAGTATCTCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTNATGGCCTNATCNACACGCAGCAGCGTCTGTTCATCGTCGTGCCGGCCCATAATAATCTGGCGGTCANTCAGCCAGCTTTCCTCNCCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGC
+
@:?:1""6;-<='471#!+@<>2);,EH=D3*A"0388;G=,2A0!$$G@+!,(?"<2?;>G8;<G$EE"/<#<<:+<-ED"0/!AB.8#1&E"AC72F<B9('B0%F6G83.31(=>&-$$%281,>.7*@HH:;C:0"E/50,3#")/8"&E=F">/6A=B&?)9D*.?A=131?<6FF=!+@?(-22"#AFG"*/22%-0&)%)4@,#H5H>*";(*B>A7$5=
@r9947
GTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCT
+
2?:/,6G6HA#9(E07?*@/07H13*%CE62#1176+#BHF@31&%8BD$D"B61,G,DH9F0/0/H/)9%!>D,'207!1<;>&D176$.<"9<521
@r9948
AGCAGAGCATGTTACGCCAGCATGATTAATACAGCATTTAATA
+
?='7.:2"/?2B%,.@:2*7G04.H"33*-</HD='6+"$5!7
@r9949
TCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCAC
+
C=0/,(C;:C@G8&F#<$AB<:39+!$.2G92)4>FH(-#G$EC7G<B).$"@)F"8(%%!5$84,,BHH
@r9950
ANCACNTTNNNNNNNTTNACNNNNGGCGTNNNANNTGCTGACTCACNNCNNNNNNTNTGCGAGGCANANAGTGNTNCTNCCNNCGANNCCNCTNNGATAGACTTCGAGNNNAATNNTCANANNNNNNNACGCCCGNANNNGGCCTNNNNNGTTGTGAAT
+
$#!#""!$!!!#"$""""$#""#!!"$"#!$"!#!!!"!#"!""!#"!"!""$"!#$$"$#$$$!"#!###$"!"$$$""$"!#!!#!$"""$!!#$#$!!"!""$#""$##$!#!$#""!"#!"#!$$!"$###"#!!!##"##!#!#$!$"#"$"$!
@r9951
CGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGNAGCAGCAGAGCGATACCGAAGCGTC
+
1E7!736:0<40?=#1E--BG%3B:96>E8&"5<#H-#F5>>,D&6,?"77!!28G)@"D8:(G7<:DD5E+BDF)1./*4+
@r9952
TTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCNTGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCG
+
3"2*2"A%54:7-A*<9,+::,7=)EC$G1:*C"/6(.6)H+C%&G&?A945(4FE;@!4<(46A5&5/A:1:!-//"D""+E30!6@5+0#7H"+&99HB74+%,?"CF)#:@2!#/FE5&3"E14'/11B-?AD&88ED841!*G5)2&A2>16'1H)$<%7).9%1B'1.7H<@/F6F)$;6+DH6.??+,+,D!83C+.92,0G9$,%H(-':B2*C:8"4%+A8DD56%:"1<%1G1#4-/@),<
@r9953
TGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAANCAGAGACTGGCTCAGTTTGCCTTCCTCNGTGTCCTCCATGCTGAGGCCAATACC
+
4B95>F33,.:E4;4/8+@D980;61<F;3&EE&4&)2'00--9%@2E5B=!1A@79/#E"$!<+0@0&1<(B%#*)'C(&5D69G?0A1+$*1D,"H(6"F14>?C.-&96D2"!B-1.))H2>--4",3>6G=@AE./('730;6'(G$#+9=0'=4%.,(HE.96F!"9D>6
@r9954
GCTNCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAG
+
)#&"G/,F<F&,@."/6H<;!,;?'F2568*#0-F/,1>5:+,$+,"
@r9955
AGGCAGACCNCTCCTTATTGCCTTAATTTTGCTCATGTAATTTA
+
?7)GC)#$411=8-HH2F("&*)$5;((&@/D!<>@H1@2F-:8
@r9956
NATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTC
+
"D6CD(,EEE$9$=&$*C'.=('5>G@4;E4)="8?"G4;#58EB;8%-#1HB:(/#GH3.
@r9957
GTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCCATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGTCAATACCCGCGA
+
E#@B#H3E!BC3F@.5=='2@>2<%E#B1?=''6=C';1$#C58CD(7HC>FH(12:7!?;&879AG!433!6?BA,:3A0;&6$E$&*(%@?(7&1/>"":(*H:>$-<68$,>.DC=6,3@F<=.6A4<-3:9,F"7G+C17$32,;
@r9958
CNCGTANTCCANNTNNNCNCNNNNAGGANGNANNNTTAGAGCNNNCAATTCNGTNAGNNTNNNNATTNANCCNNNANNTTTNNNNNTNTNTNAGNTAGNCN
+
"$$#"!##$!$$###!#!!""#"$$#!$"#!$#$#"!#$#"$#!#"$$#"$$#!!"$#!!#!""#!!#!!!!#"###$"!"#"""!"!"#$!"!#$"$"$"
@r9959
TCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTANGGCTGCACGGAGTTCA
+
G2C.&G0)/(/$''%,BA'@D5;8!<(%::/"<0=B3#*/0/#0/*-#(G=6%04'F=E/C+#
@r9960
TGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTT
+
D@?B7H#28B@>FE265!2<%:B%6<C-$;1>+#52F-&A94D%-1:""@%,"74C,D=9:,-3H2+DBH"E=!E5*H!4C)+,*1@A(&G$8
@r9961
TGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAAT
+
==,5C;,E5C4G'&#A'EC-DA.,9:%1")4%.&7GH!#6H<'>.580.D586%0+.B8@8,+D3@C%
@r9962
CGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCNCCGGCACCGCTGGCTGCAG
+
0<"<!=$3#B,0D@(%-(/3)EG<!G7?73.E9.&1,?)(+6D-7;8A21G/-;(6C6
@r9963
ATTGCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCNACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGA
+
43GE"9C*(FE$02EB6+*:(@)4!!&/):2=%H1:1(/,$"A6B#%'='';9&(H#?!!=6;+.63:"67">(%5F;#4FDC/EC*E8F".6H*"&:5:/?+2$=3'(#)/)+5D#5(8,D+;EFH-AA?3+8299=%;,6(19"@A%<2=!AE85>C,#$!F+=;D#<8&!BD))2G=*D+>/@1@>@E06B2-F0)F8&=/1D4,H,;6AH%$@1F@?+"+2,0G8>!D,.*C,-#(H%0A3:
@r9964
GCGGCTTNATACTGCCCGACGGAAATCACCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTT
+
,F59.)41E*@.C;9H>1-,()0)=2#8A$:*B2$+/HD:7&+$C-2%#@/<+$G&EA,!@E=:/G?>,"2"*$8E<)8;5'%&(5C$:
@r9965
GGTGATAGATTTAACGTATGAGNACAAAAAAGAAACCATTAACACAAGAGCAGCT
+
:A3G6<3E*$=*4@2<*-6A%C'%+==;@>!5,$2437,->+@(E/;!?>&#*,"
@r9966
ATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAANCTCCTAAGTTCTCAC
+
7/""49+/,F#&@8:B01:+E1(>6=;3?0DB%.4+/5@?.)$%)AF(%4(33
@r9967
CAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCT
+
/8>H<8'G<>5>D,9="0-&<H06*.C/"E&AE#(!??!2!4'.>2"H;&H>&/<?!#&/5$&
@r9968
GCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGG
+
H%!%+"@B%H*"(2<'#7G(@0B088H?"9*6';"9.>0>)F:)-1/=C%8=37?5"6*EH"G/3/5.<AA=E=$<0B6A.*4*9=.;#6>=/GD5G>=03A;+0@56*C3+&:(/$%/)!@;%D;C*H(/F
@r9969
AGCCNGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACNTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGAGAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAG
+
6G&:$'>1(*&3/40C>1"2>8("=$9B:$2(BFB(CF/9)$2H:60.@?.61BF)HHH;""/(EDC74!<"2>&2!:?';/'G71->;?&>';H5?=-4)29E.9D&0:,$./(@%'+#4-D.1@2C5CE@=05(5%$((>5BG2!72-#;F71+1F.50H2:E2.5HB.$->8F;;H<@#A.
@r9970
GTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACTAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGC
+
-@/==A->E@(=G!>@;$%6,63?H@E5$DH>87;";;$:&3B3&D=4C)D;9B6+>!2;@6:!&+6:9B%#..=+53(&C+F*).7E)"7(H>-90A11)?<*EH+6=B50"B88",F!=4//<F@)?/6$%*?-50B""/@82C=F9<8#.:",=*D)#)$E'
@r9971
NNCGGTTCCCGTAATCCATCNTTTNTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCANCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGT
+
!%*#!**')&$'"##$*$*%!&$!!+*)+"*(*+#&(+##"&#+"(&((+#)&)+#!(+&"")+&!'*+('"(+&'!"&*!%"$(%)+"'%'!!+%*%"%##++'"!#"#)+""&#&'#+%#%$&")"&(%'&"#$)"((%'))#+'"+*)"+*+&$'('%)")')*%!)&$#&+()'%$%#)!+&$#()#%*#
@r9972
TNCATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAA
+
5<833!5:;F>/F!H9!7@;)E19'&7/E05H;!/868$G#@<G+;(>.B5D3-.**D<!7896C-.D++<H9F:7+#?/*F*=8(.:3//@*CD2-!6E)"6*C<:*ECD<12$4/A,"D?7F'4!+<E,
@r9973
ATTGGTGCGAACCAGTATCCGGTTGTTATCGGTGCTCATGCCCATTC
+
@F(";9*=<*?G:B2"<&/5"2-H"'B#:;0$+F"*#/6A//3/3%H
@r9974
ATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGA
+
/<71>9<%3%311C3081>,!'!DHA;-4(/A:C#0.'";,:1&!A*8"
@r9975
TGGCTGCGGGCGAGTCGTCAGGAAGACCGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACNCCGGACGC
+
:3=8D+1F:$8C(>-)5B9.*%8D@H8(=52%C!A"B'4)5HE$H$&79F82H;E3';G1D4:7G2D57E;B:
@r9976
ANNNNTTNCTNCNNCNNNGGAGTNGNNNCAANNTNNNNANCAN
+
##!!"$$!"#$"$#$$$""##"""#!!!##!!##!""#"!#$!
@r9977
GATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACC
+
E6A/E68=#@%@#C8>(+<&(>&.=6!&>F9!$3D*26H0*>3=3;!=6A#&?D0:FE$0
@r9978
CCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCT
+
1B8'%?ADFBH?<HE=)?;D2AG=1.$B!-:=5-*/@2>9%9.!8%A9%D
@r9979
TCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCNACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGC
+
49%B6E28-C6H,.*9-+'5#1A<-@#14(1,FC2GF<FDC(>0E1:C:G,B$G.12:B'>.F!9B49*%$19(!%D9/;#.$4:)=.!:">$>+
@r9980
NNGNNNNATNNTNCNTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATG
+
!")&&!")*"!'%*++(%)$''($"*'(#&'!+&*))!*$++($$!+!+%(&''!'""&*%%%&+!+$'#!&&&++&#&(%'+&"%'#(%%"+!+(%!&)!%''''!"+&)'(!"*
@r9981
CNAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCC
+
+$*%*!*")%%"&'!$+*("%%*!#!'*"&+)%#)+%$#'$)$'*&"#&*'+(!+!$%!"!#')!"&'&&"(*#+'$'&
@r9982
CCATCAGGTGAAAAATGTCCTTTTTGTGGTGATATAGGACAGACAAAAAANATAGAT
+
&@!GB@?=1-F<#0(*29>D9F=68:@?.A=BH0&@?+A7=??4)-F5)@2!FD$:>
@r9983
GATGACCATTTCGGGNGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCNACAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGACAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAAC
+
/@95H").!02<328.0.<F3%5,;A1H1>+))<0@D68!F".34/7(5:9?&1*<*-D733'2=99F!7/"--#&#?#?*<<G@E9G4D*5%<D>3C/250%DF3@?C:>*E,%DH<*.D>$9*D'$>E:,ACBD'G6GD+*&1#.%
@r9984
CATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATANACATCAATTAAA
+
&$#+)#!#!&")&+)#*+"!")+"+#"#"+&))$**!&!!$*"$!%&(#(("$'+'##'($#++#&*)!#%($%#(($+!'+&#(!&''$""%)'%**!#'$&
@r9985
TTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTC
+
E@;:.'2B57#6A<-8F!,5&0D=*G0%2)"-=&A!59H0FC6>.$A15G$FGE&=@)!E$
@r9986
TTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCT
+
;H0(24%4*)64@;<0?E!H/4F=;57'G<$==F%E9G<7&$14/.)?:<D38.9@!2-F<.G#:">/0(/29;?AE3"%'?2#?57;8?-B.%9H.)HE"C88!>0550
@r9987
CTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCANCNAAAATACAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAAGCATGTCATCGTAATATGTTCTAGCGGGTTT
+
:B:'.8C:CDG5<F!7H.#$9-2@(,!-(@0H9@5G);.5$9F"@!1/*:<C5GA*?+-"%'F=)/9H?:1(7.5:%5D<4CCD":HB-CH0)-1.H/''2$E>+(C12F?8+046=<,,,"#2G$3F9>G='89*/0'AAD(?.6"(4/7/'-"E<0F@H>D56"+F60B)&A%!%AD$>2
@r9988
CACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATC
+
H1:/<A*B>.B3126*:%C*38'*HD@>98-,8=+)&*@G9%8GH(9$)FHE%0<GF'=A=
@r9989
GTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTNCCAGTCGTAATCAATGATGTAT
+
B.=5&.;B>&8;'E0D)1!G%>(@5(":!&;>/<G:FC2::B-H1/'2$*<%FA&-D/F>"'+ED'>%8#E,(*/,<#+E>+?,:F/%)$'AA2C@:.5%>&$&#6;$!@39?A>;%):6@+9:,
@r9990
ATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCC
+
9.(-?0+,+D>;D&B)3%-H/A)?><;,&7<<=.22$A>G(1649?HHB!)'(+&,D/4,8'1E9H-&1%'0&+8%?-FE*?(4-@/;6&0B0<89<.>=G(2B=2*(C=<BF=#,;;G6;B>F5*4&6'B'
@r9991
TCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTNTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCT
+
,'7HH?3H:@;)G6762/)$;BC!.C72A&%C407B(581&;6E#8/)4;5%1/H:-H5813<A6A@(4D?9FE/0>@1*!()2:#6-'5:+0G:07.6;41.+"4;!.55B=33<(?15/5%B(/?F*(CB#A>5A?D;#=<</&5.9D@8$
@r9992
TGCTCTGCGGCTTTCTGTTTNAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAA
+
H&-A*@7@5@'&?;;56%;7=A0&-4+6A2?6A!6=/D,C*@=>$+""$57?<2)(:H@E<'A0"='1,-$%%<@+,@'0=*?)?="2::>D&&!30)*
@r9993
TCNGTGATTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCC
+
'%$'%'#!++((#)!!%#($($'*'&'+$+"($*"*)''!)((
@r9994
GAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTNGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGNCATCCAGCTACATCAGGATCATATCGTCGGGTCTTTTTTCCGCCTCAGTC
+
H>7F4%@D;4>;6(7?E@=7)@+D/.(!G$@8;>*:;8+.$GD0&3)2'")E+3G*'4@%<):*920,B6H**:B;6/*(@,,+'(;B=CEEC,G'@1;!?E"?9&%@'?(<1))GE-BD&&G,6HB:&>-DBE.-8-B;F&2/B3)(@"?3(+*"?:2#2(21*=<:?4*/>=>D&/@78,3C3'F,9930%6E6D5$5)?B=:1%8<D3
@r9995
AAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGA
+
E?>(8)&;<C2>H7""C109B66.*.<<:$7@2,"@)F8B7B=#H<>',&58C%9G$'"8/D"5<&?B(*91(4>5A!6=B&+4#'=+?HGD"+&%?.%$"//2=#?)03+29-.G('!-
@r9996
TCACTNTTCATTCTTGCGTAGCAATATACCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGNGNTGAGAGATGGCCTTTTTCTGATAGANAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGNTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTT
+
76?4<59B6-'CC5)++&E(A)-.1=5@F&A<4A>&/1(1"0**7?.<+4%.%>/"<(C=*1$G+H/,5&0E</*291#@*A:%4D>0//E6H!C7;F14,+.(9/&35H<7GE!?(670;B>6+D#!+A;@9F(9($*-4*=(9;B.#G@99:+<+<:B"GD-D1%?,0%H=B.H>F@"!3"@$5H7G,A$>>#(8-&1,3384$:4+!G1
@r9997
TCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGA
+
3-$H.:DA'$342H<%"A1F2'/A*@!?6FD;75B4%=-E6&5+56B?<,5?0:!-D2#..+1"1D@FD$;7C*7!);;?&F@=<>4,8.%@1/98??9+%"C88F+C<)37?;44."1(E.*:('-)3>A
@r9998
CNGATGGANNCGCTGNCCATCNCAATNATGATGGCCCGCTGAACGGGCAGTGTTTCCCAGCGCCCTTCCTGGTTATGCGGATTCT
+
'"(!')#(##&&&!'#$*)*)'*'#%""('##+')&'#%(&*&#&%)#+((!+(&((#$%#&"$!$+#$#()%&'%++%&%%$%!
@r9999
ATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTT
+
8:0):?=,4!E<3E8>/?B2@&+,9=8/?;7;H2$3(>*48A6GA)(9+>
@r10000
CGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCANCAAACCACGTCAAATAATCAATTATGACGCAGGTATATNGCGTATTAATTGATCTGCATCAACTTAAC
+
@D%>&)<8F2<;4#;C)CC#&7-68(@9E;G*<#(./9)2F7>3>C0:C8%-(H>'+HBE25@99AD@@*12E=!#42A"&.HA?(FF%F!#8<BA4-=E'..=A*)/%%'3CH=",+@(-"B,97DHEGF