view test-data/samples/sample3/sample3_2.fastq @ 7:13539c458a6e

planemo upload commit b'7f6183b769772449fbcee903686b8d5ec5b7439f\n'-dirty
author jpayne
date Mon, 29 Jan 2018 16:19:16 -0500
parents eefdd97a6749
children
line wrap: on
line source
@r1
CTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGC
+
%++!)%++(+'!'&(+#($++!*$#%($+"!#%(+#")")!&&
@r2
CCTGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTTCGTACCAGATCG
+
"((+$%()%%&$*(%&'(")"+%*+($%!!*&&**%&!+(%"#'+%*%&""&#"&'(')
@r3
TGGCTTTATCTCAATATTATATGGATCATNGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACT
+
+')%$#+((""##%&+&+'!%)$'!#+#'**(%#!%!)*(&")'"!#'*+()!&"&%""**&%%*(&"##*!+(()&&*&%()#(%**$**+!&+&*!$*)###%&(*#!$!+''*$%+*(*'())+*%'%(''
@r4
CGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACTGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTT
+
H77#D."4!0(0@A)<9"3>E/E:3*7/D#=:@4F()AG+=C42@*?;84,6+?63/A'A.:"4DFB/A%53'19($@%,*:E;H"D773F@>=FG:G:G@G4E(8-2H=%!CG<H!<"8-@$8/<(A-)2G/@D'?/%C<C("CFA&4+
@r5
GACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGA
+
C6,8%D>8')F)+"C3$E"%4-@AE>463/6"%%56GB?&3<9AHE%"8@BB6?*F
@r6
CTTGAACCCGCCTATGCGCGGGTNTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAG
+
%$7%F/+F!?;44=D-.E@!<'(!#)-==8!F!8-<'.6"3!>=7'&4D:38G&A(/)4E+7//*:3?18?$.6-)9)5%,@+28?;'>
@r7
ATCGTCTACTGCTTCCTGCCCGANGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTATTGTG
+
#+(!+)+)'"+$((')&+++#!!*+)*%"%"!*)&(+!%%&%##*"***'&*%+!%"%!%$!'&"+$#$!$'
@r8
TCTGGCCAGGCCGCGCTCTGTCATTTCGNCTGTCACACCGGCANAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCTCAGGTTCATCCCGCGTGGCGTGAAGTGCATCA
+
0:H(HEEA2@:D9/8C2EA!@2D"'.:>&+61C)-'$212'0F4.3)82*,/2%)4@)?-,.05D,@,"/C7*73)04=&)5G.E6/6C',8>H3&D?'E11<&>2:*414,
@r9
GTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGC
+
,!G=-+!88B%.;)F-.7&-E#8G=,=/662D!@@#5#):'&3"0,':9;@/6:8@B4*3C9.C)*=(5%9-:62D<=*@
@r10
GGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCAC
+
#+72@A>5/281//+1?6*C&AA=<GDD.A8:(<C.5-,-(*;$!:&)@A8'00.!D<-*8&%.F*8?$*/E0
@r11
CCTCAATTTTCAGACATTAGCCTGCNGGCAAAAGATGACGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACNAGGTCACCAATGCTGAGATAGC
+
<2/.17"=##5@)!")@7-6-*>F$&?!H7*(AF+F+>+/H=D/6'%A%>0"<@"%9!0:5B4'F,G=(5+96.9H:+H9=A%E&("H:.3*H:1@,C$58.,;9$9;G#.;+ECC9?4>E-,9:
@r12
CNCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGG
+
()?D*769@!>><1G;<;;**62F+%BAH8A)!0HG=6:!=D"&EH@4;;+A8F$"+BEH+8;7+E;E<:&))=+A,2?EF2'+=4$E@5
@r13
CAATACTCAGCTTTACAATATACTAACTNACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATNACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAG
+
D";,&EA%1<:&:6*&1>1DF8=03102%G>9/F.6A#@;HDD;=8?--@AE:*E28AH@B-$8@%<8(H(B20"B//%(A74&H(E(6&0171..@)%F..F<(B/4>%<?"8B/CC5+78G
@r14
AAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACAC
+
C918C1/0A98.5><G3:2+-.<2#:B/%09F*</#1)-:7:$G32A,)9>(H?G0D2@8G23;B-B3F57=
@r15
NTGCNNGNANCTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTAGCGATCCGACGCATCTGCTCNCGGTCANAGTTAACCATCTGTGCGGCCATGTTTTTCATAGATCCACC
+
##*#&()#'!&+(##$%+!!''))*())&%%&*)($(%#)"''!&$+!(!&*+(#!*&"))&%+)%**%%)("$"&*#*+%$($()'$&!'%%!%%$#!%(+&&)*#("++"!!%%(+$'*)&&!*)&!*"+$'))$!"##((((##*)%+*&%'*"
@r16
NGTCCGCAANCCTCNTNNGCCCGGACNAANTNCGCGATNAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTAGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCAC
+
$(%#*$$!(!'%*#!%&$&)()(&#*##'!"&$+))!(+"&'($'(#(*$)"'(")#!&'+!+#(!&+%$!'))&'(+'+#*$'(()*#&&#"&%%+&'$!'%"($!*'%*!+)+%&"+%)('&(#(+!"(+())*!#$&%"$!+"&"&&!)%''+&%+++%*&
@r17
NTAGGCACGGGTATCGCCTTCATTAAACCACTACAGNAGCGCCTGCTG
+
#?"'H;;B2$G'.%79GGFH<39!+*;<%=;>%4*.$A4'+>C$%H0E
@r18
GTGCCCGTCCTCCACGGGNTCAAAAACGNGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATC
+
#%"+!!#+$*+!""&#%$&%+%$&*"'(&&&$$!")!&%+$*)&%")(&$!*$$$#+(+!)+*+)"&)$'"++*'!&'%"%)&#'!!$%%)
@r19
NCCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCCCATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACNCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTAT
+
'8:D?>@:2%78*060(6..#8(82,-7>G/<#!(.&(>94*'!H3$9F05-/%D<@@7'$=%",?2;9.#EA<%B;<4-$=4D(CE=/%?2BA941:7F41!()8:/23@;/3(A'0?1D:8?2!2-)471)@-EG995E=;)C1'8)E&)"+70=4F4.A)3HD/;(G+;C(/<7@5<GH0H,)@'@"1,&.$,4C8
@r20
ATTTCCAATAATCAGAACAAGTCGGCTCCTGTTNAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATANACAGTGCNGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGNTGTTCTGTTTACCAAGTTCTCTGG
+
@CH'2>G75?B>3CA8BH74"H8,8/!2G#,12C;2F!>@D?/C><DCF9=FC!112@90;@@A=$45*422+H(DD'B-H$)+244H1;80GG/;!<B9B54=B?.:9&/,/3?"9.,C(D66E72#5<-!=13?#(HB7+#@9H.??H$)#)9##/6>4"+()D
@r21
CANTCCATACGTNGGCCGCGCGTTCTGCACTGACAGATTAAAACTACGTTCCCTTCACCAAAAGCTGTGATGANCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAANCGAAGCGGCNAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATANCCTCGCATGGTGGAAGCAACAACCATTCGATTT
+
)%!'")%'+)(*%#("*($$!%#)%*+)%!(''*!"$"((#&)*&+!$('#'%*()((&"&'&)##$#%#"$!"%#)$%%%!+((!'&#+*'&(**#%%*&"!%$%)%"!'&%&(&!"%*%((**$)#+'!*)$("%#!*")#+(%&'&""!*%#"&!'&)&&!&(+'!#"+'*+'+()#"'$(+""$%$"&*!%*'*'"%")+&'"$%'!+)%+)#"$#$)+$"!$+(
@r22
AAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATNACGCCCAATC
+
6D)9BG"<F##$-7CD:>$:39>=F8'*--;E516F;>987>G.)$,8E)&1<HD("/?889*7--@
@r23
CAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAA
+
261@/;$+*#86H>3-%73BB-3>=##4B54G<E@02;E".H5!9E=3>;:=*$D'9E666/876H!1,/E7F$@$4'.B'?1)5$*0>?.99>&0;(><
@r24
CGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGC
+
+B3&3&8<G7C9DC2'@&B:/=",<;/%9B("=@)B!:<"$7)C-/B1.$&=CGB+!F;-;/<
@r25
GTCNTCNNNNTNCNAANCNNCANNCANNNNNTGANNNNCNANGTNNNNCAANNGNAAAANNTNTNACNCNNGGGTNCNTGNNCNNGNNNNC
+
"#""!$#$"$$$#!$"###"$$!#$$!"!!!!#$"$#!"$$#$""!!$$$#$!$!"$!##!$$!#$#"$!"##"$##!####$#!#""$!"
@r26
CTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCA
+
5BA76:7/$."<0(C9@+8(=2EF-6-;G<24)1"8C@7(&/;3=E3
@r27
ACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCANACTNATGCACTTCACGCC
+
H-CE>@12(3-!%A6B1FG0C#F/+/1-7<27,8D74D?F32#%%C#CB?1B/)<6E!+5D9?;9/+'+07$2&#(>/2&'>2)@3A16;7H<1&6$)&'768&,AC:=
@r28
ATCTTTTAACTCCATATACCGCCAATACCCGNTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCCTCCCGTTCTTCCCTGGTAGCAAACCG
+
7+!#&5>58:=1'3*D21!$?!:&793=?190":6*B+5A,@>F!D#+!GHDB/)$F)2E@$:10(/'7()#&>76"D:EC$,8FF%BC8<0>5<?91B0G@9./>0>9B+924'
@r29
AAGAAAAGATTATTCGTCAGAGAATNCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTG
+
G=)D=--3*59??+=F<(=("8D>G9H++:)<ED5#1*+""533(&#<0.;&6+!<D9*1#A)%3&5
@r30
GACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAA
+
$9-)-=F0H0>H69G.:*,0%!@34<#D4$)%BF708<:@A+>:'H9&F?@A3<<1!'3.)A*%&%H(/"$160*/F6HB5;$16:/,G2
@r31
CCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGNAGCGTTCCGGCGATGAAGNCGGNGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGCTTTGGTGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCT
+
&544("C4)(6)4#=#D3/C8DG1)B>,"5A1;DB(;GD'.2,67'/EF<F$,,HD1+1>:!97&<:E6@BE+8A0*(F>.<"+FF60?6F'0*@3%'C.G<"@#,(!%332+0E6-$8-C'7(:98BC)0>2:=C=AH++*#?1"C!?E=.1#*@1%B3?14<+'<CE2H&E#.?7?"%0.-
@r32
GTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCAT
+
:-F>2?'4>A+(+A<?+-;H*(6%';CA%?4H!2#*!,6-6C(B*?"20>=,0>B7,>F;3;16.A9>+.):(<&>>4F;:"0-#@:.,/@8!7&9=0'7G1++@3<#.8F:-0)$>9A9<<2"DH(<,$>"#8!75H-
@r33
CCNGAGTAATANTGCGGNACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGT
+
)"!*)'&)*&&!!%('("%+!+*#""+#$'+**!'!)("&)&!$%#+##'"$'+$(+$!++
@r34
CCNTNCTATNAATAAATTCATATAAAAAACATGCAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGNCGGTGATACTGAGCAC
+
)("%!&")$'#')+(((#'+%#)+$"')'"'&$"!)'$*$&()#)&'"##%&*!$&%$*#&&"$!&$%+*'!$$+"'(!'&"+#!&#*'$#&!*&$$&#%)&"!')+
@r35
GCCATGCTGACCGGTGTACCGACATAACCGCCGGTGGCATNGCCGCGCANCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGG
+
++&##+*+%(($)%'$%$'#$#'"$**+&*%('#'(&$'!*%%"#!!)(')*)$()!"$*%%&#+$+$$*)$!&%$(&)!$&))")&(+*'(''!!##)'&!"%(+'''+&&')%%$
@r36
NCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGC
+
$+(*#%+(##&%!&)&"!%(&&#+$'*+%'%*+'"##$#)((!!!'+'')$
@r37
GTTTTNTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTNCCACACCCATTCCGCCCGATAAAAGCATGAATGNGCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTNAAATCACTGAATCCGGGAGCACTTTTT
+
*<G;8%-A?C6=9!B)%@)A&,9A$BD2.=$'?(B6*E%*3<0)'=830#6**=)&G>#EF-CE$5=C9G>1$;7:%#H1<"@-*/')DE.9$C2F>6%9F&17:?9E<GD8:1!3%F'(44F)*8.?437F4(<3D='BH'20,3+;)H5454"7.
@r38
TGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCG
+
==68E100(*C"-C!";AD2619(GF%C/1>(-B12)0A(E%(80G+$.-3#"HEG<-@@GD""%-(1-@B,#1;31$H7?+>/'H+-8(**/271@>72BFE0(<2D:+1+6.76?-(5'7.@+5?=-H0@&:8,#A.9'/(!##>:;#E4F4?+4G+;3,E<F*<#%.!"#(3;
@r39
CTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCANACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACC
+
'84#1(,B0>//%&0"5#5BB@FG@<-,!$:%@80#5(A-.<H/%%@D-CA(71?@<#;;7A!D)>-7%H<6+*8"222>4,4?':&065"*23#<)+%+4<03B2+!7+@6F4<16-&C0!121%H)?H7>).&,6AD&89'&7:)$-B?9;E"=G;.
@r40
GATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAA
+
A8B'%0D.=6-*92GF6:/')&D<?3)$.=>.()>@7*8*H2;8C,965;A
@r41
CAACGATCGCCCGCAGACACCTTCACGCTGGTCTGTTTCGGCTTTTTCAGCGTCGCTTCATAAT
+
9*G19#@D+>/9@,6GE!DDH0%);;9(;,1"/?HG=@%"#5B&7G<5EE&'/-928)<<)#:?
@r42
AGTATNNNTTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATA
+
!*$(%%"+"))+%!"#*"&*(+++'")$*$'#$(('*%)")*!%)##+"!%&$(
@r43
TGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGAGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGC
+
4#2(:60G),""A=@DC&=&F*#%7/0('0<$$&A6?95/<3/&<8/G!C96?.@B9%>!=(H7'!/=?*$$$!0A?1GC&07:#*B$*8#<084:11)9-(A5.??1G5).E*/CF35>@?.%0B<E*>+68-A&;?:&ED=@E#$5-G36%>,<%7$/(7D@3F%:1F<77B@H<HBF%*:'C6C+217C*?2='40?-H4*0D'>%1&+A@1%33!C@3!$8./&3(57D767(C#$(DA##G&.7>20)$;F0-%0.G-.41*6B0.$,:14A&F;-C9F.+3*
@r44
GCGTGAACGTCAGGATCACCTTTCCCCGANCCGCTGGNATGTCAACAATAC
+
*E.4BEDD5*.@58B+@;11(6E5'7F7@775,446*2?(36=;/#C64!.
@r45
AGCGNGTGNCNTTCCNGATANGNGNGNTNTGACNATNNNAGGNAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACA
+
'")%'$**#!('"#&!#&&&"'""&'!"%')#&&)$#!##&&#+$)#"$)&*#(*$+!&*'*"("+'*)$'"*'#*"""*&
@r46
GTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCATTTCACGA
+
1E0@:D"FG1,H-13@,-(0#5C&!;+";1B?E@;H!G<=0!8<F(:2D)%55>4/"B'FDA
@r47
GTNAGCANTAGGATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTNATCATCC
+
$*")*)%"!'!*+"%!**$&)"(**#%%"('#&)$+$%)++!!$$+#'%#)#$*##""
@r48
TGGGCGTAATTCCGGGAAAGCTGCNCATACGAGACACCCAGCCCGGCA
+
+"$!*("&#)(&('"%()#$)'&&$)$)*+*(%("%#*)*%'''&)+%
@r49
CGCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCC
+
)$+*+!'%+&'(($$"#*)"&*)%&+%!#+&('*#)!'&%")(()''('&#*'!%(%*+!&'$%$$*(')'("%')!*&#'*'#*!&)$+$+*(%'()))
@r50
GCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATT
+
>F."F@&G8+"?C!&='B$1&%6'3<%0EEA(&?G6*%0@6"!?<7B(&C3'/?8?D153DD>((,G=119'*"46*D<6>%(:&'<
@r51
CGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCA
+
G'#0>!%4H2%<1;4,B5;-F!9#0#6?5$'8A&40>C!G#CG)5E#G>!0C1*:9E5??3$6@/@4)1;)36>0&)+/A-!>76>!6:>>-<5@(F"9
@r52
AGAGACACCTTATGTTCTATACATGCAATTACANCATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATAT
+
@"/1EE8+9@5=6BG(DE4"CGE'E3@+#(&?A*#B7C0)64.&D:!C2.#=?BG##:,(*2*2>>1;$3/6-
@r53
TGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCNTAAACGNT
+
71>DGBA+@<7!96>E254,8&?9*H9%8GF"0G?A<?6/<>E8'(%"%@E5*=1=0%#9:A%G?E24975$-&#?">@D#--?E/61,<!@@'2B)
@r54
CAAAGGGTGACANGAATCCGTCGGAAGTCCGCCTGCTGGTNCAGATACAACGTAACGGTGGCTGGGTGACGGAA
+
'@2GB&EG1-$;:?3#6:,=B'E&3/8B$:B8%1F4%)B9HB==/=/%%.0>C)'%*.:!H/)()@5B??77=5
@r55
CATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTC
+
-368)#C@4-G%@>HG4/*$5'6!&>*7+4C"0&)$$(H;;)"F7+@GHE?'@*=B%
@r56
CTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGATAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGC
+
@)FD.'B==40&0:9:F@='H&4.#-6F,B9@,B6B;&(>0*&8+77=8>-G9%65%+0'C1H?>B>E@1.'F+<<<DCG9&(@9>)G45;83/+2@H.;"@=;&D)=>9.H4%#-</G8F$40&:F"/4?1
@r57
TGCTCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGA
+
%#'"*++&%"&%"$*#%$)!"")*"*!$%&)!&)&)'%+&%
@r58
CCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTNTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCAT
+
G'(0>+G(8E)@(*AD2=/GA@#0+BD!6=C$%&<#87F5:0'(1!6>D$#=<!7E=B4!<""'=3,@:$H?H"+,-/'#B6"@<F6.:$C'$G/A*A*BD$>7<74>3(A+7!**BAHG:.#-0D50D66C)%,/H-H@,7D<)+:?6+)H@)<0B$*)3=9'5&';E)3;:6#+7A*+A!17
@r59
ANCGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCNACAAAGCCAGCCGGAATATCTGGCGGTGCAATAACGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTCCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTNAATGCAATGTTTTNGACGGTGTTTTCCGCGTTACC
+
("%<;AA'*1>C4A6<9EF*A7"E-31>B=3%>A'B";"G/19"-76+!:A*$"H;+6D5?'7'3':4+D0G.(@%,085%:%27-E53,?'H89?(3B(<0)8-H?%=>04-;G=7!@*A5?,$2D3GF%6130"4#'".!66DH)03=&2,.#$/"F3$D@,6<7AB/"1<)&B6!G/(*$-)%78DA+?FG'.8,C9E41-4(6>+#(6:>?72<?)9C4D57(!4=(>8A73!0)4">:?,2=7@-<BF>D<@020<EE
@r60
GGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCNCAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGC
+
,@=0.'03%"C'A?5,*/1%+GHC/1)9*1('DD.G=5;G)C.C(6!,-CF;9D/+H3)2#-=$@7F97)*,G--8&E5@-0=
@r61
ACAGAGCGCGGTGAGNGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACG
+
1HG&#23&D:E)":8<#2B)E8%DC7-7'2$3:<?=.;31";7*9BCE59=H$")#4$C3B12%.616%4+:
@r62
CCCCTGTNTTGNGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTA
+
?<7C'%8$"%,-.;3"H(B&+0!;F-E?>/B:HG;=B$.48B<55;C:-B7GF'&/'7>@,E.B
@r63
CCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTAC
+
=&?G@@-<<B)"@B5<7,C-1@)!-"D2(%C745%0G+:$;H)4")%%@)(&C@>@
@r64
TAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGNATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTC
+
.8+;..G!)A!1?8.A$EHB.H:@9"!9:2H%D1!B>*@/=<>!C;F;.40=A:A/,E73:+-H6'60,A)1#!1E/7HC>C1%?9/5B::0&.(A$<>F8&D">8':6HF>B:<2,&+"1;/71G31+"=840?/%4B6(33@H7$D%!>(FB49+,@,/1E8'F?942A+E+=0.,-!,;=7'E*@49
@r65
NNCCGAATCATCANGGTAAACNTGCGTTTTCGCTCAACGTCAATGCA
+
##%&+"$!"*"''(***(#)+"%("+*("#!'+#(%+(%!+$+%#%$
@r66
ANCNTTCNNNNNNCTTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTNATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGNTTCATTTGGAT
+
%"$!*"'$""%(!(%+'$++*'!+'&$%%!)"")+&)"((!*'+*#%*)&$$!)"#+#&#(")%("%!#!%*!)&(*""$"+!+"!&&(+&%&)&$$*($&'($(#&"(*()"&%*#)!$
@r67
TGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCCCGATA
+
8$$BF=BF%#F'<B!+-H7!8*#B%?2G&"@<E9!,?2A0,-+:30/2#79,*H$,A>7$$,-1%CG#2B.7E@38*CFF&$AD1H@E;.<<'8)?;-4?0D>0CH@E*30E7&;D>&'%$5<F"1(187E@,<##?8%?)/C='H
@r68
CGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACC
+
$@0-%GFA5=11F5%0<F:9++G.@;64<3E>1(;%/&,#9GD+13
@r69
ACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCCGTGCTTTCAGTGGATTTCGGAT
+
*F)765F-6:A%,469'3#9(@0!)*6+G'9<)4H'3A-)(27G(=E$@16ED,7%=.#6F@,(-8120%0-')@.'08"64
@r70
GGCGGCGAAAATNCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTTAAAAGCGCGCNTAAGATCAGTTTTCAGGAAGCCCGCAGTGCCTGGG
+
GB5(07,#3BA:G(D';"7095E!-.*?8;7#7$31BB<:<39.0E9!+!%+/G97:8!2"!>G6B4+79';3H>/37$*#!)GF5/7@!$D:3@?B51)68*F'/09DC0C.='5"7E8*;B$%,&.B4(D<5%0*%>H
@r71
GAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAAT
+
@*C!$>B".,@DA8!5BG<7C;8-/3G8@-09((CG$4&!6*#D-31D%"@7)#*;6H@<?3BH2)")#,3E18D?9"/063E65*<(F34EC./E?!12"<'$D6=G4"&//6$>H$G7825=+*D02%<8/0"7!H1D(*0G,/B@%.@
@r72
TTACANCGCGATATGCTGCGCTTGCTGGCCTCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCNCGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCG
+
AC&"'##)53:3&-6#A8:@4=&>1.6(&=D4-;E@!FE/?3$/'6,CGD.($-EA7=EH+E%AD9?B32B;(<3>C1!7AD@@.C6/BF)9?D%;@B#H:D"*>!62H814+G416AG:##6BB#A$F<A67+?2?H8)&43/'!B0'>?@;DD<5+%
@r73
TATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGC
+
42BF-!=(7-?'8%&=C)B,?6)1?#8".?#)&?/H;'5E%:5=3';&#3*3;7E!9-C>39+$FG?!-B3C1109E)4H>?E9)H(3;
@r74
CCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGNTGGACACCTCCANCCGTAAGCNGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCG
+
==!8:G.D<DF-4+A,F5650!'-!E5E.3?.$+%)>'2=5975<3?3#1A!.?%>;)%B-$)8.;C+'2.!E1>=(E"5E'?%0D8.AG?))ED?!."/46!,9G6(
@r75
GTGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGC
+
9AG7G0EH>$C#?E)0C*DD5H/)DHF!#3,*-"9*(+*52G"./4F;1#+D6B"1G.E',
@r76
ACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAAT
+
1?ADE9"927>938.0"=*'(,(A462D*9*.&0'H!56/G?4*(B#-)&:$<-8'(H%:,&,#13252F6:E''#A/92C?H19G$5:%&(9A+=&!+<,+.0#!(6$<A2!,B#0($668G1(32A$0;1&>#3>G-4-:,
@r77
CAGGATTTTGGAACCTCTNGCNGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCAC
+
633).?.3D@-&G-<(!%$!(9-;.>"!:A<!"4,&@9#)+,&F,&$!4'G;E)69?F3F%0D3&$5;3!7D9F@4G"4HH)11/*2('A=3&)!$0*""04;&40D3==);HA1/8!>(G7-23)4<-,'080B-*H&/C5C0!0($46*97+F2F$:!C='3%:/%HDH.@1&+6A&:3HH7-+AD?4?*;.3"#+G$<"4B.A2/(890/.;>8<.)58H"6G4.*!>G/0902DEE0A9$6)H=>8>-E)F>E/GG!G9';G/H48%2!;."%%=8C
@r78
AACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAA
+
<#A0F<0)=!;;'ED'%,1G-1G0)@-51*9@D<57+$GGA!;%!A0&3)&*%,9DHGC6!(>A0&&%D<(+-:42+
@r79
CGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGGGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTG
+
'1C762)):)()0.:<,'$8,>'B58*#5B2679@,F,)=?8.@H%@(4<?C*-EG?(8GH,")1;?%HC)5C"$66%;G58>&(-8B'"-+G0&0.$/$B,=B1-16"=(
@r80
NGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCNGNACGCTCAATCTGACAGGTGCCT
+
!++(%*'%)(*%$#()#$+'()(%'##%()+(("'(*!*&%$%!!'&%*%($'%+)'++($$*+)!$"!#$(!+&#"$+""**+%&#*#&%++'"+)(")")#)
@r81
GGTTACCCACCACTAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTAATTCTGGNCTGC
+
$F$/G<,#@B1,77%-4/@;&(3%@%=F?$E/4A54F&C()9.0.-?#C(@.21H4':+?@CD'6$2@:$2*3@=*G6G971$@E:6?%1.3HEA38(G7.)=82E&*C6H>="E;,.$?4=!BC3,C7DBG*DA)C+6AFE064)
@r82
ANTGTGAGGCTTGCATAATGGCATTCAGANTGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAAAGAATTTATTGGTGA
+
$'+D6AF1@A/G6:D+*DE(B?0.=.6(E=!3C$@;(=E0**3*A@1-F98CA@1G;G$(583A$86.'$%5(+2F(=!0F*<217=4'E/?0E;,$
@r83
NAAGCACGGCCCGGACGACGGAATCCACATACCNCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCNGCAGCACCGTCGAGGATTGAGCTNACGCCNG
+
!"+('%%+)#()%!+!""#($%'#+!'!*)*)'''&*"*''#&*%'%*#)'+*()&%$!*'*!%%##+'!$##'+)"*)##&(+)#&)()*!$++%"!'#*%)*%!$"&#!(!($$$)(()%+*$(!"'!"#%+%+&'''#(!(&'#')%('*(*&)%&$(&'&$*(!)$!
@r84
GCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGA
+
G7(B?C+5%=$=#F("'</@<?E&5-%8#4&HB5<<;#F;3:$->75"?5!/HH=9,%*1$27(#8;@7)?%
@r85
CTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGG
+
1D$&3=(")B(*D5C3=6;>*AC>*'@+D(')88&'*&',>(D<++?8,(5+1<51D#0+8,,;B>?6F&%9G9<>(G%?&/0BFHAF0&@#:&#$
@r86
AATATTCTTATNATCATTCATTATGTATTAAAATTAGAGTTGTGGCTGGGCTCTGCTAACACGTTGCTCATAGGAG
+
C2)3>F12E+*13%-/',FB53-.;/(-'0;00&?9(49+8!@&!E,E.F#(HE>47B<*9E#6&<%;*550-<1C
@r87
ATGTTTNTNGCTGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTC
+
')))(%$"!%#%+()*'+&%!(+(+&!'*%(&%&*$!)')!+($$))(%'"(!%'$***)'($$%&%"+)&#'
@r88
AGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGNTCT
+
+"+##""'#%*%!$#(((""&)%+)&**'#&*##(+!!"##)*&$#($*+'&+#!!$#*)+*%"'+&&+"*&(%!"+(+&)#+$+&%+!#&+&+)')'""&($$+"$+$)&#"
@r89
GNNNCTNTNTGNATGCTNGNANGANNGNTTTANTCGGAATTGNTTACGNTCTNGGGANTNNNTNACNCGCTNNCGNCNN
+
#$!!$!"""!$!"$!$!"$#$#$!!!##"##"##"""$$!#"#$#$##!##$"##"!!$"!#$"!#!$##$"$###$#!
@r90
GATTCAACAGAGTTATCGAACCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAANATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGG
+
'9"'A0EE6A(=2=&8*#:02:G-CD:6494#B*"7+A>BE:C9(=6"@FB=$G'HA/A?<&$E5>:D%>:7*-+&&>AA?H>>.*%E#B%D+)/H2,2H.E-(2;B$8!1!$:7$:<&66(+67=4A1C%>/7
@r91
CCGTGTAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTT
+
6(,0.AH:;A8+,G2<211"!2(*:?&.+!/1:/"5C%/3;.,7D7!,?8!,:
@r92
GTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTG
+
B'@D@!'0B#'+A.(&@+;#D$A*B<"HG+@2G'8"8%76&BA
@r93
ATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAAC
+
->A)9&A>C1179(,G&!E+&H;;<0A7)H9@$-;G8:6.1#'>B8>'/*.!%-3<?
@r94
TGGGCGATGACTGAGCCGGAAAAAAGACCCGATGATATGATCCTCATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGG
+
:H!4*.!8+'DD!32*35%%FDH=28D98&B&0G/9/.&6;=.4.5B20"39F*D$-A)3G#+(/":F$(2*&/F,*FD6HC4(4:/G=1$9/-@?:CCF?F5'G5-1@B,84-'/B8"38!"9&,FG)"&">
@r95
NTNTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCNGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAAAAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAANCTCCCGCATA
+
#!)+%")''"$)#!'%$)!*+$()!&*))%$+''"&!""())$($+"+&&#!'!$(%&%$+'"(+%%&!#!''#)+#*"&$#%)$"''#"%*'"$$"+$"*($#*%+)&$"("&&&**'"()&'%((&''+"#(+"(((!*("++)+%"'#)")'$)+%%"(*"+#&*$*"&'(%*&
@r96
CAGAGTGCCGCGATGAAACGGNTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTCAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGA
+
.5**=<GD$'5&47-/5-?$*649%3!93.>5/!;+@&>(<2>.HDF-8./>4129.4H=7B@+57$F)=C!:%<G?2+B(,7H#3=!*&.<>>."%%EGCE2.F/566-D/0&
@r97
CAAGANGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATNGCCCT
+
AB?5A5GC-"9E14!7?)*92.+3.7BB+19E+,.<A0>DG4B,H4$G5(19>:9&HG'B<8;;3';575#2A'&C@'#4/(0;!".>)<2>5*-8D/'+?2>(B
@r98
CGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTT
+
4*%=)"$H9.(30>=;06)%>H(/&<;/"G):$*:-0,/*&5.@B*H#3F>F2(!'%>)5)2<)+/)!'GA9!GE!"-@'9;60D4."@-),G*BD-!;!#<81?0?GC?6$/6/<BF+0#<CD9?'!@7!E"0@3D.970:=>>A;;)#C2@+%GGH"0,;.E#B?,80(E(@-;9A.<9:/1>/F;$8F.%"@HE@+3>/*73@G6%=<'GH"5/(=%&=$7D602/6)(=4H.H?):+)?3CE5#+
@r99
CACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGNTTTGCTTCAATAAATTCTGACTNTA
+
:$G9(*:HD-7&>#*#)>#-G&,>)&1,A?,2.A44*$&*A)2GHA$&D7F4'E-%5/D.&88!%)!9A*2B=D!77?G>(?267,@E
@r100
TACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCNGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTGTGGCAATGCGGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACANTNCGTCAGGAAAGCTTGGCTTGGAGCCTGTTNGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGCATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGA
+
+'<1E4?+G6.)?1")$41B6D).;:79E@56C@*(6048?0/0&<779+$@1BFE6<E?,C"2.9!-?3;91'=%.;",")A5@1*E!HE:4'::0";0%-#0%<A0*6@<">53&$4A52&:<)">(-G22%6HH3D?<';&<&;'G9"C-)-BFG-46..B,@;67H$!G7>0EB6F<%C.DA*(8/:.$>,..?DG.2090,)'0.@+;"+'A>B&&2;<;2&0/87<DBEC5469C97*&).>+(#B"@.$F5;4!#,,H:1#8EHHG/<?-20ACFD<?C5(-
@r101
AATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTNCAACATCAGGGTAACTCATAGAAATGGTGCTATTANGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATACGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCANATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTATCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCANCCAA
+
@HEH*&"7B20D/2$-(HD=B%DA67:4F-!"E#=6,"(AA=?E-D4.=0HD(75/<3(#(B@9#6%@*$>3CC1E+D<#!G"?%F6E,E0>2H+@3%<72'B>$.*'"C/)AD(".E#7&E8=:36@8>+>+@7#!8D/C/G@FB*#F6/@0!0.A':DD$AG2F-#=('H?'C)085G*BF'57EA+&F#(,)4%2G'0/.77!5-A;0@;D'H(1;$:0A28=H3H$B(%=8E57'299@?#3/)2$3@#>$,0D$776-AF)6,3=F4(:B4!!3+94B.AH($2>
@r102
TTCCGGCAATCAGGCGGGACTNACGGCAGATCGTATCCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAG
+
(7#-13*1%3<@--+#=2B,4'6!G7/G";?5B06!71$)%H0=$)7FAD.--&"!@A%6C+)?D8"/<D)DD:$,137/*'/+G25$9F$$*#&?)3D&4G*!#98DD5'<%/H<!$0+6.-GH&-"%>D/EAE0H#B
@r103
CATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATNGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGNCCGAATAAGCCNCAAGCAGCATATTTGATAGNCTGGCGNAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAA
+
%CD0D27'&#6@01DA!52@"4=D#A<2!0=,G82'5F5>82=/:524,!@C;'%E+"H)5-&EFB)D:*84-H+61<C85BAE6+'G(1:0';H:5;0%!3/#;<-H*(H;>.=%D=G')7:<4)-)&.FD(@E"35/$57:1':!-!C$#,7%*'E'=2('E;84;)87=;G?#+#'=*:#3/C"0A4:=B&#38(-,@5(+,4.$,:53203+D@!,9/*)484%:0A-8;7(81*C/>>1.'7!0%$,07!@7H>*3E!>&@+?-0"A-(G723/+10?9EF..84*(19+-!6:3,4;9?2G"/?4D7,!H4
@r104
TNCTGANTACAGCTATCTCGATGATGCATCAAGATTCAGACTGGACTGCGACCGGGCAGGGGCNGAAATCTNCCGGAGATACCAGCTT
+
(!%($'%*+)*")&(%&%"$#$*'"!"+#++'*(*+$%"*%&&%$*""&#"($"%+!++'()&&&"($#"&)$$)$((+)#%&"$&(#
@r105
TTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGA
+
0>1>+>;CE.CDFB;H#>@+FED-HC9<6>#7?6,'!F2*5/B?0CB6<
@r106
AAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGC
+
&H-#//12%G1#"/@:4":-HB)!/./&=31:=B.-E"9$FH"!3=GH)$G3=1;"<D-H2<8E1?+'(
@r107
CCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCT
+
51$7AD<?+@?3@81;H/H&,*6)./>F/)F.E1/(G!E0@*#
@r108
NANATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGG
+
!*#+!"("#&)#"#!*($!$'+%*"!$'#'+&#%&+%*)!+'%+)''*#&$)")#(*'(*#'%&)""&(*
@r109
TGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATNGAAAATTACGACGC
+
;>HG65-/>6$$91;,/E;($+1G2*&!"306;!0#*!?46DC/<>(99:;0&'94!CF$3<1.&/2-$
@r110
TGGNCNGNTNTATNGGNNCGANGNNGCNNNANNNANTCGCNNNCNANCNCNTNAACNANNGNGNGCAGAACTTNNTTANAGTGTCNNNCTGNGGANGNAGGNNAAGTANNANNNNNNNNNCAANGCNGNTNNTNNNNGTGNGNNATNGNNAGTNAN
+
#$###"###$$"$!"$"!"!$!!$!$##$"#!$#$""$"!"#!!!$"#"$#$$##$$$!!!"!!#$!$!!$##!!###!$!"""#!#$#$#""$$$$!""$"!""#$$"##""!"$""!#""$"!#!"#!"$"!!!"#""$""#$$"$$#"!"!""
@r111
ATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGNGATACGGCTGATACTGTCGCCCCTGCCAGGAGACCGGC
+
=;G:D1+D<<7D?0&6<B*>F96BA?2$69E#<96&HA>0FA=C*EE967(A:7572?3?H*'B<'"7G)9:7)#';1>;(B4;05#A(@F+2F2&4E19D9D<#&5;38<%$<1GG8A("?9=8!/97-.;5:9FB?<'<#F$
@r112
TTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTGGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATNTTTGACATAAATCATCAACAAAA
+
04"=/@)$"@*$=(8D-AGBF>/(DBEB;&(@DDA,:(?70"C$.AA26A.%5E'6C-+'0.H&3!&4<H2E8%)%A&16D8BF4)59<C%D1DH5AD,&C)2(A.E5C**FA(C*=0C&-/.D'$.2'C69'H2F),E-;2)?'('("=G",#2,+3!"2F#'5/?0
@r113
CTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCAT
+
A#1(@D=!-!D?9A7494.322&@,F<@>3+9G&HF#E;C,1C-7A$5DGAA!:::4:8(#'6FG?@#A&;G!!:/9F8+?(#BE*=+<A>(@+G*#2A1-$;:&8B+0F*58!&
@r114
GCTCNNTCNGCTGNGGCGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAA
+
'($)!$))%)"#**#&!'+'&*&%&"$&$&)+##!))+%&+$#*+#("&*$!$*)%'$)++#!")*%%!&+$%&"$$%$%!#)++"")*"%**
@r115
GTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTT
+
E"H:E-7<9*FH5-=EC*#.5<2F:=E9//!H&)2)+G5DF##>'B->6"2G6!3EE-D%1$GDAA82C1##0(=
@r116
CACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCNTTCATTAAGGGCTGCGCACAAAACCATAGATTGC
+
-)9&<<-.4>-A)?551"1@4&-=/%;4G5&!)#)@48*A3))@!%,(F7&E5@+1(!'@=8)45/*&%@03G86!.7($
@r117
TAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCCTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATNGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCNTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAA
+
7H#C+":/@4"0!?(;5-(*'B#C3'>'C-8=B60H835HG.6$4-<1C='-9#E#4"42-E:B)"$1(#G?DD).@H?(7<??07:;A!9%(.E1BA$/$HA2&<%5G4F=H"D%12<'#+:?><!5DF+1/G+:<C&A<72D,*%4"%(1CHG1H=".:H>$:2<+9C*9!)6;,5=3!40G-+5'"<##;6+H.E0F>-@66.!HC#47818?1$.@B:F#(1C@)</DB3,35@B15+3?GF%*;,+,#97!4>:5/C'AB?3%'<>@:D7DC"B$4EA85)4(5<8H>;2#7%69C9(4E)-H,F4-E2<)A.@BAGF1)"G'3'C
@r118
AGGACTTTCCACATGCAGGNTTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGNGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTA
+
)D((<A7@->36C?A"(#)3E7/2)7GD&6@6>!809B!&!-%)G#8E?F&B.H-3,>CH-,6*-=72B%)@CE!86'0'E#8:'4%(E$.2(14>H/#,:9*0:*:G8$-1%7G+$1>F;3?1G2>5..G-"GH2@A$>*7G%D*=+@(.&BG/AD5,B>4.&C6/=&%A7'EG0$C<E+'G?!'#*<;98G
@r119
CGTCCTGATNCCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGA
+
C&F,"+EA?520?C(02?=)0$/!;=303'*8$3+378023%.AF/%9;@;.";F,/0=
@r120
TGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTNCGATA
+
?>#9&);87@BB"&$H59&&:68HH9!,G68H!D>G>(6=%F'"G4;D>'30+C7G"C7#BC.A1C&'F5-=;>(49(4!G03&4=!$24<4$DDC5-/:)CF/9C08!0/03G<E9F5$#9<(<'748CBG$*#!,6
@r121
CGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGANACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGAGGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAA
+
BBF?"*"G.!/</5).B)$B5/!1FC!GG-/.*D8"F<F23-3$*C5*1.GG6,1'$1/58#;78/(0,!=:)7=;4<@;..4CF&%35*"-"!2#37E<6.@E>,%@96:BFDHF5E@9*,-758&!D9>!016*G'7H&$*;BB1B"'!B!$6$-(78$3557,;$@5E"71":14F%='/"?3)-856!=D1(#8+<.A/<'+!G7(1=1C0'F)&!&7#(G23C1=G/@16F;&1,?D(GHF&+@9!%,,;.'.?E-996+#;C@2$;;-<<0D*FG>GHEAAC&,;(.5.8'H5-6(%'$E0;#(
@r122
CAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCACCCCTCAAGCGAGGGAAAATCCCCTAAAACGACGTNTAGGGATAAAACATC
+
%1&!9>(00)B:G'%&*3+/+,F?":(B6!:46:@2&G/%EGF/>,>)30FG!D9$(;5G2#G<1H-2??$HF':69C25BA:/H64<1,C)6B2H7*99)@?2C&:>;><ACHC#B,!
@r123
TTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGA
+
<:'#+=E2/@<%3D:&*;!*-#1'D:CHB%+(-EA#+@A>%+4"?F-==A
@r124
GGATTGTTCACCGCGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGC
+
/?.7@CG.)%;EBA%$?A'+;7:B,5)6@>:0/;DB,%8G%D,/#$@F1#DF+0CH;0)H"H1>1B'")B4#'2<3?<!4;0F1C6=.;E=
@r125
CNNTNAATCNTGAGGTNAAGCCAAGGCCAATATCTAATTAACTAGATAAGAGGAANCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGGACCATGTGCGCTGATTC
+
&!#)'(!*('&$$'+&""##+!)!$$%+!&#*$")&*$#+)'!$#%'")%'!##++%)**"*"(+%(+!*"$#+!)((*##)+&#&%*$""&$"""*'&+)%$&%*$*("')&'#))*&"$!'*#*)$#'"("*+
@r126
CTCGAGTGAAGCGTTATTGGTATGCGNTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCGTCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATT
+
2@F8#?3E!4C(?5HC/<4"<.*3$F1$A:'CF#G;1>==*2>.F0&C701#8#F+9&/0%/89-&=H>3?HB;2CACD>D7)".1>@:E$>F$EA*.&;4;*6--(=3+(&@(>@7>'#,*/%:-</>:<435-:*B-33BH*-G27C5G"<#$+/@@(%CF-5C$9C%3(;7&?7('FB6!0A.FC<A&
@r127
TCACGCGCCAGTTTCAGGNCAAAACTCAGCTCACCGTCGAACANTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACNACAAACTCATACGTACCAGACAGCCGGTACACCACGTTT
+
;C5=,>0A9;A@*;5C"$G61+C=;#9+3/,5+C"G6'2?5A%;%9<&"=>DA+C%$:!C!'=!@(C8;H<>0)4%*65DD6/E;>3%B*06HH(/31H8"%?"CB./&>C(6B51<!+;;03-8<>972A=7*78(D$=3:9+=;
@r128
ATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATA
+
H41+<:-/14BB-C:GF'-7+C;8(;/04AGG@E>2'D0)##+B%#HF2:6=C?"'A5=:,:88?<3D:6%-%DDA!==1"<9"1!G.."17=0)))0>==4')AC'
@r129
GAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCNGTGAGAACTTAGGTGTTTTAACTCGT
+
997$3FB.<08A)!+D::AB3'A@:")@%D55'%+"@4#9>.3GB69.>99BBB,H;!<76D?A1HH1
@r130
TCTGTTTACCAAGTTNTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTC
+
$6HC;+"F)1;C01!-'&%!D:9+3B)B5-41#<@&GGG(1A1$$!D#+'1#9=,A:F#+(@?FG
@r131
GTGNGATTTCTGCTCGGCGATGCGCTGTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCTGGACCGACCGTCGGATAAGACGTGGACCTATCACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCAGTT
+
$#&"'+!*)%)#$(+$"!)&&!!'"!!#&'#"'"'%&##*$%'*"))(+#+#+)!$%&"(&%)#$+)!()%))$$!$()!!'#('#)'#"*+$&))%*+&*#!+*'&**'')+$")#%"()%'$&"#&'!)!'%%&
@r132
AAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTCTGTACC
+
5,"!@DE9+=73H:;D42AD8>.H2=<?66,:??8E!@@*7)F/>7*,3!=213DH/9875EA(!5*9A;C529
@r133
TGTNTCAATATCCGGACGGATAATATTTATTGCTTCTCTT
+
'&&'+)("!')!!+)*!"$&)$)$&)&#)+%$*+!(*(%)
@r134
TCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGNTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACT
+
1:D#C.E%";72$;F!F,>6$:*D5+8@9*&$=5,C3F?2H)$.G'*63/894(.9,B6F*CG(4G<HC9:$A>E=2?4$A/H@.99)FH!*'G(=3?>69;2ECCB#/A$:
@r135
AAANTTNCTGTCTGCGTTTCCAGCANCTCTGTTTTAATCAGCCANAGCCCGGCCCGGTGTGCCTG
+
&#(""$$#(+%&%'&'"$+))#($$!)(+*((#!$(+#*)&%)+$*$!(')''%%#(%#&$%#((
@r136
NNCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATNTTTTATCCCTAAACGTCTTTTTAGGGGN
+
!#(4#=*+G@*3"B+E9?<:1&G.:F-6=4A"A**$$-+F2(;AAEB20FB-?9/2B"1B2>;!>C";$@,4,$>G>/!GBG2=;0,9C*.3!:D/*G2,+('A<)#7
@r137
AAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGAC
+
8D/(#<(-36C%(A@F*>*/+-&$,DF45!;-E)#D,#!'=E?26H(9H@7>D
@r138
GCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACNCGTTACGCGCCACCTCTTCCACNATCAGTTCAAGACGACG
+
E:5,96+!2.6A3'%E:918)C)%,6-F7%C#&G0*270/0GF2>7(<$8(BD&D-C>G9.5B@"E<;<#"7DA>3;';-A=;&9#,#1D%6/)&*C%
@r139
NAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGA
+
"A6:?"4486E=;8C'!4A!2>,.&"-@E(.)-.#(G.)(.6
@r140
CAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGNAA
+
))=C$(:?3"C60400#>5+?B@(#01%H=B$C-D&+!.E3)8F'@C8=>1+9G&.4!:<'5$:)B:0&%E-<7.(%$"6C98/(
@r141
ATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCG
+
;54<8$@73EDC:*A=%-%"E:8''??A,#;B:?!38@%"+E48-6
@r142
GGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAA
+
/1H!H.")DC4D(9:-(?F*-#)2D@A.E98>79,.'@C>#4;,A3B6)="86E(/D#@@-F&<%G0F!20;/!&"6FC3'3;D>4/G+D0AED5&0)7*<14A?B%68ED?5,*%?BB-1A1>4!G%B9
@r143
TAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACC
+
")&GH)#(H1D@,F6&.!.F03'HE?+).:=;#B)H&9#),&H<DC"6,(C=&?AH8)B
@r144
TCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGCCCGGCGCACAGAAGCTNTNATGCGTCCCCAGGTAATGAATAATT
+
D.7578);G>&7$1,/0A/4B*8>7)8"')EB"G134#,6HF??0G9$/+>@5<1E$/G;6/<H&2C/&45>)>45FA?7'3G./BE?&2*3+"+A+$?BF2&D*?E6"'B#H%B=6?&&"':G6>:2-!5-2:?G%4&H4#D%D4.57$(570'863E+'"-85$A%7+/!08
@r145
CAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAA
+
33E"(2=(G)@3D";.D9$-.?!A'E".?)A(@.A<,!0.50H))F0,@?7#C3"G=2)'5>$<B0%>;6G5>1/;4A+:G*4/B4E$2>4
@r146
TGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCNAACAGGTNATCGAAATCAGCCANAGCNCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGNCTGCCACACCGGCAGATACACGAAACGCCGTTGCCGGCANCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACC
+
5F(>>19!+CG,D4&7-A(&<>7E%)H+:$>8'.=0,7,+3,E&7270G&&=8,,$0;5,;.%6*03>HH0C"%H&?*/*A7$5=C'%?8&1*G8>)1B#3+-4$7=="!+#B(>/;8<A#>+9$#=*DC$8/8F47%0?6%!:/8A44?6?:<*0H/?/<A?1:!1HH4=D(7#+HA"?,2BC&3-@%EA5?50%:18"EA03H)@8@?9G2F2"-27:.$:$$<
@r147
AATGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAANCGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTT
+
FB?-E)7:1$'6%C6.;@67"C!5A*CA71=":6/>83FEA!'7==7)C+26$A1+&6&"<G:/+<8?%%?!<1D!"@CF7/A/6):?.4-E3HC0G295H4C7<6.+B8CFB:
@r148
CCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCG
+
'*'&$(*+$&(*""(&)*!+#)%"$)&'#+&'!#("+(#'&"+*'&(%#
@r149
TGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCTGG
+
66>?G9=GF?CA).?.+B.%9E=/&1(G48628?:2B3G!EA;3,2@0A++9>-045*@0%G,D!,%+?DBH"CF1>AH:/=
@r150
GCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTC
+
>2"0&"7'1D"@?>G@<*.;00G7#2521G*<G79H87E?)G3#7*!35#'G8-2?B#:!7,+H&-F8*%%GF529!E9@#7,A+&<&B6/8D
@r151
ATCATCGATGTGAAACAGTGCTACCCGANCACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGC
+
0D8#@/4>C!)BEB7-1"G,.G3A5)?%!/D3@$;BB68F!2'("7F".,%61E+F6E,>G?0&;1+:18<2GHC!&G@"14-2A"H
@r152
TTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGC
+
.1//280)8$%52)E2(=EG',?.0$F$D?#1H(?8>'A8;2G?4<@6#0=(#G0B=<85&9-7'.8#0&8&A242"-,D$>5<<8>>%!5B12)"EC/:4G+@?9/9&4E"9=*&89%;A@&=7-7"=@9'<:$"F+'3<BHB'C1A8;%<<++$F@,/1CE;(673,#/341E%;"<(,<8C(#?2#6?;0073/$"/,$<@(=!9E60E."3(+-,=AD=*>52-2*?*"+2B/#.D3A,!,A5;,
@r153
GAAAACTTTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCAC
+
C5H!D%0:)=!8:%=+&@.&(;"8;G<1EC:8;.'4)9G0-6,D?<B-5#;8*!(D:%#04E1G/%.":!#+D6D:02<:G.1;BE7'8"8';9@-5
@r154
GCATAAGCGNGNTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGNGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTAATGGGCTGTTAATCATTACCGTGNTAAC
+
%*"#""!&)!'%('$&)'+'&((&*#(#*)$$$!)!&))'%)$+'$"&*#!!(**)(!**%(+)&)&*#+*)*$&()+((**(((&##$"+"((+$((&&+#+"+"#$!)$+$*+#(#)$('#!%*$*('(**&)'&#%*!)*&!$&#*+!&(+&(!($%)('%%&'(++%!!'$)*(&!&+)&+"!#+("$+'*)#&$)&+'#++"+*))&**#'#%$'$'$&)!)!+)"+$)%#$)()
@r155
TCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATG
+
!*:C9:H(>?>&C>2<86:<E&4A67G,41:43>)9%.0%7<;8(20H<'<@;63B>BE&&7:+F
@r156
TTTCAATAACACTAAACTCCAACATATGGTAACCCTTAATTTTATTAAAATAACCGCAATN
+
5/2:GA@G5,+"10F!6+??:$2>@=72A"$9+@=B+(!A/366<$A7/D66422@>F,!6
@r157
TACCTCTCTCGTTTGCTCAGTTNTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCG
+
0ECE?C%/5>E2/)*9):0",(A@0/E:2.0F?;E'&D($<65)<.#GBG(;2=0$>!!&+G!/9D?*26%H
@r158
TGGGATGGCACCACCGACGGTGCTGCCGTTGGCAATCTTGCGGTTGCTGCTGACCAGACCAG
+
>+04(.99E2<835(0"=9,*2F5<@+F@">5(:?$#A)/#'7E86!;0'$(%H-'G+B:@%
@r159
AGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGAGGTTGAGGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTT
+
FFD.A.,+"CF!3/&'(2(@4*+G2F">9A@?<:8'A(0H&)-/72E%C17$<H"'&(A'6C+@93,B&(?0A2G:3"!3**1;??G)EB4>9";>?$EB
@r160
CGCCTCCCGGATCCGGAACATTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTA
+
%);9==C9*6541&=8:038:/=>&/1!><@F%G,?>$GA;?*&8B;D==(;0D6..34=)@D75C%+#2&#17:6@;@C-@>'3:>D9=3<'$>0A
@r161
CTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTAC
+
06$>28*03C6GBE?D#%4!H)*%A2(@'5GE:3H&1$FF&+<".1:4C<EF+4BF47%BGF-.!
@r162
AAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTTGCCGTCAGGTACCCGTAC
+
/6@:F)';?=2D&(G+F;!!$:GG:>!$=+'H9@--<.*2(>D@6=9DC3D+A@7.@#G'$E%%.G&>3&);=%)(:)3?F9AG>)8&C8+B/G0$F'GD1"4C++%,<:<@,G:($<ECAB5)6!:,%#(%$-7>9@BD8=10;6-F1H$67"=>#!1%F%$F6=%;8<G3H6%E=:&D*62=1FGDD@!
@r163
TGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTNGGCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCG
+
&G";F&>60H,C4$-@E,31$3'/#89*(C/=>.A'32;#&$=(A&FG4!C:70B+359GC#)!7@')5&+0?39FD99%7&<>3$#F.D).(!>#C9:"A<D*,3#3A0A$==@G5G6(0,"D)=*(E6,3ABA$@5:A:3>8&F;5@$(3>4983C)F68A-69H7H(9+A&7<46A.0!80!$#7#6</$4H29E!749-85#:F"3B420"H+,1#
@r164
CCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCA
+
C5'!C1D<230?))'F:B1D!?&>F9"/-&5F465#6)%8DG=>H*%.E&?F-%:%B'/A(+8"!"=1C6:E!91:)/H)3.H4@4E4C(B%84"!194G13--B*E%A$<"+60:3/.01!+(#.(BH>HH/>#E?AC%*C+0,2+E%A=$99'%+A.24,D7/=B;/F8;F1=AD"EH=G7/&-0!4:H2(=4
@r165
CACCAGTGCCTGTACACCGAAGGTAAACCGCAGACGGTCGA
+
B47/+6B8>4FFABCC=!9BC0+(%B!?(*,%/!(,'6'1*
@r166
NACNATNTNGTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTT
+
''*#'&%"#)*$+*!!'""*!%"('"("(+##&'$'!!$*"'+$"#(#"#*'$$##"'&!!#&$")(&"++"&+%"")&!'$*!$%(##%!%*'%"('*#%+($'+'$%+*!%*%%%(%"#"'''!*&()(!)%'&*++($#$)()&
@r167
GCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCATGGTGGTGTTCCGGGCTGGTGAGCAGGAGCATACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTG
+
/6#%3(FA?5#;<8F?:00@7--=719A'9:8&"/+$2AA<".;";9";@#+58H?)%D'@(/%BB115H0C#A(/;759)9?23('?-6>&903+-81/A"*';A&EAF"6<D7)-:#C4)F@G?F5/4<-3<;'8"$*ACF>%FA5E*8?4:A-H(A29;53?4;D-83F8/7*)#6?7G=7'7:8-;2@H=)(=7GCC8BC1$#B.@-=F18
@r168
ACTATCGCCATCGGAATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTNGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATA
+
>"$F<+DC-DH%.D-4>B$BA%?&*=++(/4GF'(2&#)E2?B.'45396/,79'H-'%7-1-F4&=B%35.*,H;E8(9'#<A8G/&3"%+&!"%->'#1--=%'8-2+4&DG96?GAB;D/'&::<8C%;BFFH/.H=H/0,AC/36@G2<:5F79+?$D4H(!!>/BDF>1=
@r169
TTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGCGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGG
+
@(&>E.$1,'G;6$!4<3/4;43G$"%2-07'G2%7F++?!$6+2-#;&':3<FF.D3C69%=7AD-3,.:<?=E!,+=EDA+6@:%=$8@2D$&@E!(1@4*#<@ED:F*$8=C7&/:CH.9.@(,-!-'2A.18"89(E%9H8!C6)B&#,0!$F6=)&=A91+H:(@)%2$6(%9:7*DF9&'A#2E+&B965),F5"8!6/:&4A:<+945$H+-%0?,H'.&,4F
@r170
ACAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATG
+
"+$""&&(+*"'()&!'+('*#&+"$)"(#(&)()&&'(%+!'#!)%+)##(("#%'#)&(+(&'+)
@r171
CCATAAGTGTTTGATCCATTCTNTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGG
+
CG%C$92G%H.6=5#&33)@D0;>36DE:>#"15A/1F:0C?.:&1C,5*/4F;=8/F1+6H$F/<CG#!-@'34H*#32G@<<
@r172
NNGTCCGATATCACGAAGGATAAATGCAGCAAATGTCTGAGCNGTTGTACAAGTTCCGCAATAACG
+
#+'!(&%')#*"(%+'%&#&($*'"(#%)%$*)"&")%#'"*!"!+*+(''&&&%*#*)&%$+!("
@r173
NNCNNAGGTNNGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTNGCCGCGAGAATGGCGGCCA
+
%'(%%&*")$%+#''%%$&#+$&$%($)($(!')"($+&!*'!&%!(&"&&$#+&!%"#!)#)&(*$(($"%
@r174
AGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGAT
+
.65/!48C)7<2.E*G4#'&9?.FA?=:BC;%5G1GCEE#;/0+*GFC?8=+8<;21-54#74,86A6@C>#0D0>2'=+111274H.A=%4-G+#;#?H-/)8(/!)@.0*69*5?/=DGD#!83"E?(A@""+%>);=38!F=
@r175
ACNTNAATGTAACGTAACGGAATTANCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTNAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGNGATTCNCCTGTCTCTGCCTAATCCANACTCTTTACCCGTCCTTGGATCCCTGTAGCAGTAATATCCATTGTTTCTTATATANAGGTTAGGG
+
!)'&!(&*+$#&($'!'(*%"(!($*)%'#&#"$*#!(!($#*++"$)'))$#(%*++'%+)(%!&$!*+*$''$+''+!#''+!#+++('#&!&#$)"&*!&)'&''!)#)&$$+$!''+(&)'+#+$()&!+'#"#)))%!$+*'("(+*+!#!)*($!")#&&&)*'$"'&!(#$#&'$$)'+*%!*&)$$&#$$&
@r176
TGCGCGGGCGTATTCTGNAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGA
+
:%H#*@"BB#1H+*/57EE=#@*9/H898A;4=01.1B&9,CG<77'%%AH9<&:96%G@"G8(C>(4:$
@r177
TCGGTAACANCTGCAATCGCGGCCAGTACAAAANCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGNGCCGGACTG
+
5-.<?=G'2)4D!B/#>,H/9+9092'0'>"0=6;+$><(?1FD?$=F)#1D5%57A4H,(;03G<HB-=GG0F<*H@A">&4(<E#*/)6'592&?FH,0:D1:21AF;-
@r178
CCTTCTTTCGGGCGGCTTCAAGCGNAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGTCCGCGCTTCATCGTTAACAAAATAATCATCCTTGAGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCANCCTCTGCCTTAATCAGCATCTCCTGCG
+
.#F:0B:<.G:(G7%=67DA:F$8++ECB+"HG*+>'#>=*0):B3!2$551/&'0*B@4?!=>>0.:$;$;&6E"3;<2*4&'''H:48+*>E08+*>=&)(7@6D8=!!$"GB?%C$79->(/9@>GF,+=(;;.;FHC88(H:5&D#542H(!#/2
@r179
AGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGNCCGGGAGACACTGCA
+
2-<&<!H'!@$G84.7:D9962-?!2,(7D<(.0!%/E<D>%$D4'*-GEB8?82H9&HC*2
@r180
ACCAAAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGNAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCNATGGGTTACAAATATCCATG
+
+*$)#%(('"$$++"%"))&!*(%%'&)&$&+*$"'!!!"#+)#+')($!"*'*#''!*'%*#&($"!$(!%(*!!*(%(*+()*(!*&'$+)+&"*%+!"+%!"(*%!(''%'%'$"!""*+%(*%)%)"'"$+&'+$''()!&*!)!(&!+("(&&")')(+#$)*$*"%"&(&'+%+"'*"!)&*!)###$)+(%+*)(!#!+'$
@r181
TAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCNCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTNTAGGCGAATTTGCGGAGCTATTAGAGCTTAT
+
G7)-5:$:<BC3356,:D9'$4+%45::/E;!E./@4E/0(+!%0?)//87&>8'0E@F6&,D+(23,?0=!G%A06B3+H;*#9.<G/-&0H&@)'3)")>'.@@9(G3"A42DD5.467-*4&?."<+E<82#&6'4!9E8?H<C*ED52G%H%F4(%?>6A@1)DA#C=,A:%:?G@G66AD/CH'1
@r182
GGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAAT
+
*F,')B/4C',B'A81$05G*)F?)4(*($@-,24E3.B6)>@A5D728G6=71;'#87E8C.;=2+G;)<H+H+0;8:#,15A
@r183
CGNGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGG
+
;8H5B>?$4"5FA70E3,>$8AF&4B/B1*5>-H5.A2.@.(E8BH1G
@r184
CGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCA
+
24'%)"#!3'+<F/C"$1"37;8=/E9.!?/0D3?"!:@##-
@r185
CNGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGC
+
$!%<(C$/,3%9D<"&-B;,5E74';:+/&=D#3..=H#6+BA,=A*<*<,54H8?(7&F40B>+G<40G,
@r186
TAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCNTACC
+
1<DA-E.?238(>8:D=7"(@4!1FH5?51H8*H$"32>56!%A#DD10+69@9$HF)962+G":H,*#G?9=??17F$:*&-#A+(E8+'#,*54406E+H18?-;49EA"-A0+CH2F>H6-,.C+:)/+(!4*36;A(=%A>
@r187
TCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCGCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCNTGCCACCGCCT
+
-(;%A*#&!0*3-D,<'-0'%6;//:='6?6#H3:3!*.)3*.&<A"911-CF+1!CH@@<F;/D0:!=C&8;,&EE&96C"".)<;07"@<1828<>!6)D83!*$"@/@DH#+E48<9;%23F1:+E>7!0?"&%H,C?;*95@05G7A;7/?H
@r188
GCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTA
+
A+0;B4G!95:59F&3F)!:1.(+3$B%;(:2!(D350D*8>+6#*%E<;F"*#B0">79-$1'<,5.+7<>3'9/7)(,$=$F;*?.09$#.71;+:#'!8!581G.H''DA!H9.):?G(%=0:H1
@r189
TTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGG
+
$8)"62(B-H:D-B"5@HD+>.?#;(G)+7/,(&@$(!(=
@r190
TGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATNCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCTCC
+
69/=-5-??"@+3683.=+F,$27?C<&"><+@%44.:,59A5"6,0F*,$+36%@($+";F+;?:.')G:5C4*F?1(%99$D=3!0?3);4?*!=)#!,0/",4@6(?=5<()G#6*<F?<5<%DA-(
@r191
GTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATAT
+
=F$B"1;!>0=>2E575E0G3$D@34"6$)96G,'E"!+4;<=A3@!;8/32'.:--'=)H;.B!A1+B+3<2@;HG&-5!76H*6($/!#AC%
@r192
TATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCA
+
A<D>9B.G5,<)-"-48,/<*F(DD*%7)6?;=&<;(272-++(H:?H:#7:854";5-3)A9().!
@r193
AAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACAT
+
&%.77@)B-$H"%F27>:@C,'#F)+>):+A8<&DG>D4=/F&<101E3$':0<32A+2,?-2+=)=2F&H9"?4,,G>#..?!B#0"B!<+*G3'DAH,&;0'-9A:-3;6&A;6)8*
@r194
CGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACTAG
+
>@<#8*9@C7HB1GC%B2@*FH&-05?!A!0(*4H=H,)GD:6H.(E&!(#C%7(=&1'C)$1-F,@C:EF9+31<<H872A3$;<:F8?A?$<4;519&EGB5E(5@*</>?;:'G'(
@r195
CTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGANTGGTTCGCGGCGGCATTCATCCATCCA
+
DE/<0&6H@=@@#H5A-7/8B&$>.DG":B.4B6:1A(F8/!>-?-*+H:$9-::;8+;=?!&9'#2F4*+#E92H74/+))@+5,74#1G<<(,;=2E5
@r196
CGGCGGCTGGCTGAGGAGATAAATAATNAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATC
+
*"+?C9<.1"F.A;($=('<#34"F1@FE09(,01#D-@D>.!08;0>A8E'4:;256#=+'CH!5*<A9;,:)8D&'=*
@r197
AGAGNCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGC
+
0C5F-<-@#3>54<A#$1-8-=4C,G*>&;?5C=A(.&=(=E4H;=(!+-%+/C@3+A#F+.%,0B?0)0%
@r198
CCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACG
+
9$/F+#47D'E39:4=+9"835E&>%-=5*G=7($>1G)=E615'))
@r199
TGGTTCATTACGTCNTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCNACTCTCATACAACCAATAAA
+
::*+3"<F&#=!B;;$#C+2;#&+@6:)!92')GG)82AA'.F<8=!>)1)DF2$G92E<8:,)/(&,*%F/4-+*&:6$('4;8*'@15.;36C<B,41@(6@587GF"E8-41)*.FH+30B;/:&5G%!C0#F/F<
@r200
GCTTNNTGGNATGTGNGACTGGACAATCAAGGGGAAACCCGTCAGCGGTCG
+
%()$!$''!$'%##)!$"+$$")""*'"$&('&"##+*!'+')%#*#(!)(
@r201
GTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTNTGGACGTAAG
+
+)++%)+$&$(('("#"(*##"'''!(*$!")$+$!+#*&)''()")*('!#')#*'"#$()+$+&#"!"*'!$%*#$&&+%*!*"%$#"#$$"("*#"'#("!)))))*"#'&
@r202
CGAGCTCTNNGGNTCACTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGC
+
)'$%(&%"&&&#!%)#)+&'&#''!!$*'%#)'(#%#)&!+!#*!("'((#"!!!##$*)$(***$*#%*
@r203
TTCGGNNACNCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATG
+
)(())"#*(&'+*!%+"')'%!$+$)&!!*#)))$"++)"'$)(#(#&!!!&'("%"+*)*&&#%$$#$))*"$('#**!&&
@r204
AGATGGTCATCTTCTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTC
+
?,+/B@H285)8)=:;H)D7=+E$""$!<C:7!G>%:F99E(-F*H5!*,BD8=>
@r205
ATTGCGGAACTTGTGCAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCG
+
H4BA?.:D/<A3/E43A=*96%!BH&D.(9-&&-.:G9!&$<85'@5D<:/)-AH@@G3D%!.*E!7!;CH?(G%?,%6<=B0>AB44B(=
@r206
TGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGACCAGCGGCTATGACTACCGGCGCGACGATGANGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATG
+
33BAA&2*(-B$7&1".D>A:C,B<G=3DH,C>!H-6/.74=0"9'E0A8'/,5>9@=9C5=G#E>56>GG9.#:%CH5<!=-'B;$"0C,5/)DAA>"A=C&&)3+C).1:@#'.-A/6#+1,13F28:+B@G&;/7).E?.E(H,#$44.2);/0+=&G/=5/9G<)E1'>,1?0H("0D2E;ED@+94AH-C@,-02H":(>H&5(*,9;),<6+!*,%'*5@H7*$0<05/@
@r207
GCNCGGCAGACGAAGGGGGCGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGNACAACCTGAAGTCCACGCAGTTGC
+
26C*7:3.,7E*3;?0C#;(.1E?22#D/H#C)%&?92$;C()1@!"H3;GBB&,HHC@-&>?;'2-7!7,;9()/='9(FC3A5!+D!&/+49$%5<5%G63>B?4.28$&$;E993C(<6(7<-6.=B/*,$:"4?)/?!''0D'=B?H2@35G)>7H-70.F"!@1C==&%7-B
@r208
AAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAAC
+
/83*?'&,=9D'=!3H=5AH;B65#,3)@.0;A<#!/?-*940>+G<&;A&C!E53G-0/0E%6#7<"=;A:#.?A/
@r209
GAAAGACGGGAAAATCCNGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGA
+
6"0#BB@/G#/3@$%0.@*/A&A-<CBF*/)81?C2?)%);(8&A5:6"%"'<G5):!2F!$4;B<FH97$F4@+!H',<*692H'DAE4+;>(>D2(H3!
@r210
TAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTANT
+
-9";>C<?1@D466A(+#"%?0<9ED'$:+/*F@B(,H813(&*EA%1>;0048!!D''5;;(5+CG.%F?-*.!(,D*+FCD@/4/!7&FF*#-%3
@r211
ACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCNATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTAAACCAATACTGAAAGAATGG
+
$71,CF"508-00G9;1=>!=!%:H7?@2A#@"5,2$#=//$241!'<%>%.$8"B:3BG3F%:F443?E:<..28A0:;E)1D0?2?#&C2%3$2C8+B')3$+H94?&"-1=3D6H!,85/H0/>/+H.:E8G:H$'.,51,=9=$)CH@$2FC/6+<?602B9&-,F(!3FD;>.GA64B,,68(7
@r212
CNATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGAGTATCANCCAGCAGAGAATTAA
+
("8(@C1(A2C7#=2"/3>>(DG&&22!H13+C>H>''E9HF3:)&*&<@%2GE0E'F8B.?(G!*577D%5/
@r213
CACGGGCAGGTCTTCTGGTTATCGAAGGTACGGTCTGGCGAACGGTGTATAACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGA
+
;;$01)>*":"/:8C#5AC71$/DA6/8".&*!2-HG7&E*>#C=@@)8>=,C3);&"+8H;DDFA>&GC,E4A76FG@D&>7"16&:',920-#<'$"<B,G:71$4B2*0A)7C((63%%?<$!:HB!;@
@r214
TNAGTGGTGGTGCTCTNCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCA
+
?84-*/;2-%!3E%C?H?3&"8H*E*+-<))G!@48F16(0.%"B'/--!8;6:75CC2%#$)@?6)A8G%,)9897&*0H+=2/
@r215
NAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCG
+
#>A@+?)"FDF+H%1#,6$:/'-4FCA-&4F2D(-1%<')A7
@r216
AACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATT
+
:*,0%6B)8;+=0:=H3!210>,!E(.*BC304+3FA"->7:D9.4G:
@r217
GTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGG
+
)8(28D6H2*$<B+5H333!G<0(;<F(06&H./;.#C3"&514.75$)"<E=B.H
@r218
AAACACATTTGCACNGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAAC
+
;)!*/=+/E);+E6!E/%>(3B>@7,4!EB&4>1.>:>HCCB(?13>/
@r219
GTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGA
+
6':HH4GC=92$"/$%'=%3'CC>/.-?1*,6+:H%:$3H+%,+B3:"7H!'$E/(C3.&1D6=
@r220
TTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGA
+
&%+*+*'*%&&)#&"!#()+$%)+*&!'#!'%*'((*%%'"%'(!**!#!&+)!"'+)#'*"#%)'+#$%!#$"%+"##%"#!)&$$!(!"'%('(")(*$&*!%##(!
@r221
CCGTCAAGGAGAAGCTGGATACCNGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGNCCTGGGCANAGCGGTGTC
+
BC#E<EC/6.$B2E%#GD0&'%*9>@A,B':8@8=B&@8%2<#F;:H1$GH!0D676$:==:5D(!!DH0+51/..*/8/G:
@r222
CTAAAGCCAAAGCCTGGAATCAGATATCNTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGA
+
B9%)<+-$+1BE@(A)C09.+B)A5'+&%##$5<='6D/3'CEH65;+B><"?5;5@C2+-(E&:8?3D>.-2'G6=""E10C!9836<&-8H(>.*-<E.@G9E2+6;/4"4.=FG&,%3;BC$C0F+7HAD4%5D+--%-C8#B1C,;::5>24-A?;%8:08&H;4."DGF2!)/,
@r223
GNCAACCAAATGTATATCGATACCGGCGCAGTGTTGTGCGGNAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCNGGT
+
*$-=C'29=,-HB$"25/:83;-7C0C+2*18C2:A&:*/@$6,7"!C+AAB7!#)?-5"14&0FF1AE,E2!@<?;A=;59D>E:=A@9%71>/-9<@2*H$!(>+?.8E58F78#1#::&C4:+E0A!)6'=>:93/H<72464?'H0H(F0H>9+)04F!/-?2
@r224
CGANCTCNANNAAGGTCAGACGGAGCAGGAAACTCACGCCCTT
+
)*#)&!(!"')%#+)("(()"(%!#&!#%$!'$&'&$+##!"%
@r225
TGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAG
+
G0%B@)>C&0@F#&.8@*D)8/(%FGG<;*5(=D38A7<3@'&6#EC71(&#'&6B=C91G+F",=;48<B+3B.C:?D;<H4D9;50=09)*=D22+(>C5C:CF1(F1.9A#6F3<.&C9=A973&;H.@"DE+AF=97(A,5@76"C=/0F
@r226
TTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGAGGCGT
+
58!+&D1G=F?$FD=B=3H;2767E52<#+?(6':+/"195
@r227
TTCTTAATNTTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGT
+
DGE)>/832<7*"#!B+6-(6?1!"#;.3;1$3D7EF9$AD468B#E
@r228
GTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAG
+
EC,6<,E&>10#$1(2>,7H.&"H'/'D?,!#!D2>;&='<!2A":F
@r229
AATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAANTTTGCACGGTATCAGTCATATCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACNCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATCTATGTCGTTTCAGCTAAACGGTATCAGCAATGATTATGTAAAGAAACAGTAAGATA
+
(+%!&((')+(($++&*$*#%$!*#)"#$+)&&(&&**#$*#)#")#"++%&+))&!&)+!&#%)!&$'##()##(#'!&+$)$%&($**$"&%&+)"$"##'&&"$"#!&+%#)#!)$!#(%"*&('+')(!#*(!)(+%!&+)+*!)#+&*))%%+((%&!$"(&")!$+"%&$((%!$#'%+*)***%+%!($"('*#)*"%$"%+!)*&$&&(+"$"#""+$$&'+'!!!#"$$!'*)%)%'+#"%)$!%'&"#'#!$'(%(!)'&''%)('%)"""&$#'(%((%)()%(&*!&(%)')+"+#)))%%'#*#&''$!))"'&&*"*)''!)%)!%")&*%*'#'%%$*$'
@r230
TNAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGANCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATG
+
$!))<3%/;1500"'4/>'*BD401&(0G(@?H$E?:,@'<1E==,7*<#&6(?!:0*/;H=;,=!9)9(HD+G*5,3)1E*;))+1$@.2=-+;,;9.7343'"<<7H3:>28E)911A.0#9A+BGHA>0<+:#*4B&541$?@A79&/G!2"5=(.7#E5=:B8A=F*,:(
@r231
ATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCNAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCA
+
82$#!D9.-E0D-;#40<E/6:/%71@&F,8#-'5)3:?BCH%<'7C;EF&+;;"4$2&$5A2?6253-D:&!!ED*7)7GEB64*9<)=EH2ECA).A@C,%1F)D6-"(63#H
@r232
GATACATAACNCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGG
+
(+$&&!(%($*%$"&!&!$**%*#$&($%(+'!)&)!"!!%!*)!($')"))
@r233
TGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGA
+
5F07F&,#:EG'60A>0/4;2D&B6(8A/G,GF4E8;:E"3/93D$9.D<$/"#8G(C!1:08C4,#).#00+,650HHEA67"-A
@r234
GTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGAT
+
/:+#78D?&28,A+)%:$7;,6B>?*=AA*84D,+7<G;7>B
@r235
GTTCNGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTNGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGGTGTCAGCGGCAC
+
(*)+$'*"'+('*$$%'+%()$&$*!**))%#+("&*!#(("('%%#!%#%!("%(#+)#(+$")%++)"%%""'&&)##(!#'**(%*#()!+)(+(+%%#'#*+&&"""+*!%&('")&+##%(&(#%%$$"%!(%(!
@r236
GNTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTNAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTNGAAGTGTGTGTTTACCGCAGCATTAAAGCA
+
&)GCBB'B;$31.*!BA902":,%,FF,H@-=E(,+1:C(1@!(>+?+1+&))GC=G,)$H4;(#&G>"GB!--6,)@1.%F6B9>)<,9<!&:7=34A2@H%0$->1*,&"59*$;B7GG#CFB9300")/#,$8>$22E</:.%8:D@HF#)F!-?1E8%$GCDH7?+'$&7!EB60'EA'17@E>03",(G93C
@r237
CCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGT
+
>6#:G"*'3@H9C;8%4,',C<,#(/3H).&;+C8F1C:ADF
@r238
NGCNNNGNNTNNNNAGNNACATACCCGGANTNANGGCNGCNNATCNNNTNNNNTNANNGNGANNGGNNNNTANAGCNATNATNNNCNNGNGNNTCATANNNCNNCCNGCTCGNGGNANTTCANACCNTNNNGNAGNANC
+
$#!$"$#!#"$"!""$"!!###!$$$$$#!!"!!!$$!"$!"!"#"!$"!!#""!#"#$!##!!""!!#$###"$!$$###!#!#!!!!"$$!$$$$$#!##!!$!#$$!"#!$$#"$##$"!"##"!!!"!$"!"!"$
@r239
CNTNCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTT
+
!"#$*!"++($)*''*&&$(*#"&("!*&!('"''+)$"+("!+%((+*&#%$()"))*#+*%%#+&$!)*')')#))
@r240
TGANCATNCNAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCNTTCTCTGATG
+
()$%##"!&&#&+*%&+%')($*"(%%*"))'*$&%*'!!!"+&!($*"%#(*!'%"&
@r241
CGGAAAGTGATGCGAAAAAAACAGCGTCAGACGTTGAACAGTCG
+
:H2.?&+C6#3-D0A9@(4->F0"=#*!@:?,!"3A51/DD=2@
@r242
NCTANCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTT
+
")'$#(*))#*&++)""%'(&)&+#+&*($(%$*"%!%%$&$$*()&%%")%#&+*&)(
@r243
CCTCATCTCCTGCGAAAACTTGACCTTTCTCTCNCATNTTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAA
+
+6+B;40/"BC5;A<!*.8H+?4$A4@*'2AH/>-51G8:8?=D)+@!(D.,58/A>%64D<3#<06=.9F)7G":>!)1%=E;!
@r244
AGCGCCTGTTTCTTAANCACCATAACCTGCACATCGCTGGCAAA
+
:":#%+,A/+>)'6;#4>G<,HF-7#.*:H='6AFE"D>&);<)
@r245
GGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCNCAGTTTCTGACGA
+
G'7':05/=$/(=;4*-'+(2#E4G-A20,90FF>61,&?$0C)E234*D2'.4%61G2E'G;%4B$."A+?D>;-%D;'."6!)8E&&4?C$)E=3@D@>#?$,GA(/3F+:A4CAAG7'B(:;:<!1.+B1A9,4@9
@r246
CGGGGCGCACTTTGACGGCGAACAGAGTGGCANGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACNGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAA
+
2>7=:B41E.&8@A*CE99G'/1!$F?=7,G?G6B6A$#1G&A7$/'F($+/*15:5$7D/04361*)GC-(7)&2G.DBGD,(.A$-=99CD>"@)G0:6??2911*#?H2B6<FD)8/G=7;,A$:AB2)87%;,C83.%30.($.A&3F8H$G?.G.G2A0;CB)08/64-D"&!52!)%)0>4")**$)419@4>$'">G(?'@-:?<-A158!+?H)AB
@r247
CCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCA
+
?:,58%E)6"%@A6;3CDF389EG1&%/,1+G?&./3@*15--G$(HG
@r248
GGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATNATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGA
+
+&'(+)$+*%&'!'$')$*))&&$!(&+#&)$*&!#%)!%)!!"%#!))'++&!!$#%*''#**$(()$%**)($#$''+&*%)$**!&")**")!%!"&#&%"#'$!"'#%!(
@r249
TCCATATTTAGCTTTCTGCTTCCNTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTNTTAATGCATATTTAGTATCGCCGAACGATTAGCTCTTCAGGCT
+
7&-84>+D:1.'+@B$/342G/-<;1;!<#(#DH239=06$A%H<548.#.D/<55$+&#5>*;",<@542'!#3.!:61'!G03>9D?C''9$,/B)+>;FH$9:5:9(/57?'"">5'H)0/14%15
@r250
NGNCTNNNGATANNATTNNNGTCANNNNNNNGATNNNANANCCG
+
!#$!$#$#$!#"""!$$#"!#""$!"#!"$!"#$$#$"#!$$!!
@r251
ANCCCTGNCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGTCTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTAGTTA
+
6.,C?-2A%?BD@@8$FC@8"DH!?'%34/@D$B3A7;-3%1845$$F(2-'=#B1F4#;>#);(,9*>$+6?80821'':&??(01%3%9$42:,+G5810+(G)0'761$-$3).0'$AD%4.>B*5!7;HG<*C977#+?+%(
@r252
CCNGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTC
+
$*#&'36#-'=$%:F:?7C6&;!A&>%?&5'14C5G%=9/<232>==41$:)$):78B9524$F":(7>>&.#@3=3H#5,D#"29@
@r253
AATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATNTACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCATTCCCTNTATTTTTGCTGCGGTAAGTCGCATANAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAG
+
+00'<GE*"47'))B$E4!1!7E7.(,*4"@H!%#;F<*':?G@"E!!!)949.5&9'E%)#/G.*C@*6DD6*H1<@-@E"<HF.+;((19&)))$:3G@(3?"HE/F'=D*$/'#7?!*'7(G9D!0-AF:%-!;(5,H:@%=E;,?=1)6%)B'E1"CF7'$8.*E-(F?7*>03A%$);F&0/C)19;;,G%",ED247!C*+F$H.C*6,)<G33$4&8?:?3'H3:/B'BD5.%,*$B7=D+(.5!F60A'#&
@r254
NGNTGCTNGNCNACNNAGCCGGANCTCCCCGTATACAGACAACGGATAACGGTAAGCAGA
+
'#$(*')#(!"(#!&#((&&&'%+$)"(++($!'*+'*+!'&(+(%$)$""*$'"+"#$+
@r255
TATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACG
+
BE>5?B%/;474H1E/2!79A=(:A><B?4(<)3A:2*0%@E>)
@r256
GCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCANCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGC
+
C:H'=5B<1=%-04%G=A%23G?2!2@'&9;-4:4,3.)+/0,&;))@D/;+3@8:=3B%BC2//,B68.)1D/*1&$F=44/'<&/3=4B,!D&8=556?5=068-..'!G1A>.+##F%A$!G6DE%"EH@$32=?@E<<1,7%4C-!<585B(H<(*"/*"A7/A@=%/G(C7F<4C(!D:&./<:@:B:4<:7<A4C4>'C2&=)&7<>09'F5?98D?50#B.F79D6/*"!D09<93D02"-H;.B!@(?&31
@r257
CACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTT
+
F978D&F#@5*.@:=<H@/'&',2*H,.">89$:F5*21AE?1B;:9)A891)'0!!!34'4%09):@03!>.H2BB#5>
@r258
ATATTTTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTNATACTANGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAACATAAAATNATTATTTGATTTCAATNNTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGCTGAGCAAACTTATCGCTTATCTGCNTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGANGGGTAGGCGGATCCCCTTCGAAGGAAAGACCTCATGCTTTTCGTGCGCGCATAAAATACCTTNATACTGTNCCGGATGAAAGCGGTTCGCGACGAGTAGATACAATTATGGTTTC
+
:.3H:36H5C."*B@%2F"E50*88@65-:@7.B?4BF061DF?07GB?F2'0?G0DH07=;!,E2F86E7D809#C'3E5:.&864-G7GG;$?GE&$E'5+3FB<,&5F@B8;'$&!*C1#:H"D%!3,6A-93A8!D.-A+G9:!88HBE82:9%!5*<+-%-8??$"""'+0:$>#4.)2*.5A#;H>)=*+68+A<@82,.F.H6))'G7C8&EF5-6*##8B;0*759"D%'E3%1-/A5"8/9@!5&DA7A5$DA-)8)',%'$.)''8A%2+D)!D!':&=>4<))6(,54-9D<!56-$,A5)#F!$00=F?'C$,F%<2.'-$46,>'"53</.)D;';&/18&$%7@'?H,2(C<-&,/(.'7A')3:G4G.H1+)&A#!?4
@r259
GGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTT
+
C;'<$$&@9,HCD,$G(<*#>GH86.G8075+'#>;;&E@%G44#(.%!2*
@r260
ACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATNTGCTTTCCATTCCATCGGGAATAAGTTTTGTTCAACACACCAA
+
A4<B;BF%/?+")($DEF0*-)7/>A8=36E-/(E'8C2H)1EG)7H*@94.,3H*8A*8=8?"(F<&7E13'5@<9H=6$B!8;
@r261
TGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCNGACCACCGTTCCGCCGACCAGACTNTGCATATC
+
,'"E=@$C!',&1*4'G.6A*623F<*C8)-C;F(,4<59##:;H"F#'81/E:&4E,<,&+<+.!"<'#G/-%',@G<#%;)3C;E'#:D)+H=8;?@/:F4H9>3356=CF(%C;6'G=54'-:47G+(,3=6-.(G)C8
@r262
CAGGTCTTCTGCTGTCACCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCG
+
0H%/263;@<"5H3@BF,'42/+-*7.1<G2!08A-?(A;17>$2B+-A3;991GG.?6GH4!;5+F4@D
@r263
TANCGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGC
+
)*+*#))%)$*!''#!')$+$!)+'"#&$$"(%!*$!()%((+!%"(!"*+"*$!'%!*"""#($*"'#'(&"'+'+$!)&!!&+)%"''(#
@r264
CGCGTAGTTTGCATTATCGTTTTTNTCGTTTCAATCTGGTCTGACCT
+
$9<F<4)(BD;HB$G$/?B%=%*-/??)7F=7$,C/(!9"!+;%G0H
@r265
CCTGGCNTGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGGCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGT
+
DF>7+>A9!>04-90#,C$+%CBC-7/;7F+#6@+#&#"'+;*27$F13360/A,/H4+$06G%C3D&6/.-3AG75(>#G?E>,@;0.,>-B8%"6EC-$/.!8!0(>C<)F3,G.#%)3%7-
@r266
CATTGCGTCGCTTTTTGCTGTCCCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGC
+
G?+-D<%/4$&!5.017<5GGDA(@4/@1353A3'3$&7!HDBH51EB.6A6'D+=.?%!):!$<0-:B3;/H
@r267
GTTTTNTATTTGGGGAGCAATGGCGATGACGCATCCTCNCGATAATATGCGGGTAGGCGCAATCTCTTTCGTCTACTCCGTTACAAAGC
+
:39E,(-;G?<#G@;.:,36,./*:E7)!;$40$7B?C-##:&"*HE@7&+3E;E3=)+AFC&:$A-;14!.:H1'3#.F/D90:15(5
@r268
NTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTNACACCCCTGTTGGTGTT
+
!>&(*0C3HHG>=:0!,A,'=A832,$,?*B5:,H$?7<?4C;&=1@';&*3E/56'E:?0
@r269
ATGAAAAAGACGACCACTGCCAGGNACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTNTTGATANTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGG
+
2!"C/,/A/&G/674C1+?(D(-54@A1(CF/!HA19&'@"1="3&(G:93G:=!E+/&'))>?;C.#:):*5=)CAGF,@G>D8.:8#.;59C10','*/1*..C&.$9?0$+D!C(+D!5$=B$715;1=1E&GD+3GA#%2CC:F//@+CC7*8>)4#7'7178#H')8-&+
@r270
AGTGTTGTTCGGGTTGCTGATGCGCNTCNGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGA
+
#=>"<<;'?,5,-'$45+!/1"(>$"55:9;7?)5D476CC.=<H(A">&H3BH9C/*802"08#3
@r271
CCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGAC
+
>A68:!"66GF01F&*D/-B/7/=03D/75*C,<(E0:<$/08(=9F%.,);B2E1&>6@))@!*EC".$)4@;=7:5+'(47,B)'
@r272
TTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGG
+
!CE;(C%<?6$82FG6+@H.F"C&2@B>:/"-)897=#/5/D/
@r273
TTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGG
+
(?7&E%G)!@8"B70<9#"E/2<?1G./:>=*?<4'9!?A0-7"$)$"C'(?6E?'H4=8;/3&7(6(?,3B.1&06CB-0*8:,(C5=GD>==$E
@r274
ACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGNCACTTCAGGAG
+
9&:956:,GH:8>60')(@>@'"FE'1:$#'=B>1?")&2,.;<.*.>:,35E7>><75<;:=4G?CAAH!>0F.78C*:,:/,!
@r275
GGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTT
+
6:3=,8:B=-?//5(%49.4".;</+0*'>*=.C'8?=1?A
@r276
CTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTNAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATT
+
9AF$69F=<B01&04.#8$&C/GA1&B4&.1(/-=HG?@.#1C:%&-.@&CA8300H?7;(>&22,;E:.54B/?E"55:
@r277
CCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGNATATTTCTTTAAAAATGGCACCCTGA
+
"=H<!#<4F*C-9--4/@G4:*@?G+F3$388E'4;5(.8E!$%7E'ABC&',D#4%G>E?&*3
@r278
AAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAAT
+
+8#B(6#=-81:)#,--D=D/</-8")>%/F%(8+2@A-D89D'0);$G8EED:E@4>!)E0(D8794FAG2?%'D@<F!64H3D6-.=6$
@r279
AAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATNA
+
FCC8#A!0D'-9873+4):@7"?0*7G&G#H#3-2;5-*%+,-0=<80
@r280
GGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAANCCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGNGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCT
+
15HA&-7/:H4:/H=&H2/#1,6E1:G!C?"."C4G:33EH.+!EG#!!/:+14>))#*G7:4E*'?("#767>,C190#;A<;B7H&5G/'88.BC<9CD9:6%9:@A<8A#928(!B&2%*9!8$:/5=&#4<?,9&<D"H/9:<?-H!!B%6!06E,=E?0.?E=C56B0E4D!8E0!5B983964'76-C7
@r281
AACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCNGGTCATATTCATCCGCGANAGCCGGACCGCTATAACCGCAGTCGTCACCGC
+
2&F8#8#/2*&;E4D.(G4HF?:=$'36"#E?&4&&E+(5=B#6(9'%91(52''.@413.,,2!4<'(8"8D4@#/=2'5222BB:(&-#$>14+48%?.1E,5,;'4"A
@r282
NATATTGNNGCAAANCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCNTTGTGCATACAGCCCCTCGTTTAT
+
!!"'(#("#!$+%)#&(+"'*%%&%&!('("#(&""!($++')"(!(()+#(%!#++#*'+)&#$)'''!$%"((#+!)"(")$"%!#'"'(((&
@r283
GCGGCTGCAGGNGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCA
+
/>,C**+",)9"-03B>%1!11=7.G.7%:9(?7:+E1#HAB0"4/46-,>E*"0982,8B-"!:8')!-4B)%*6H.&/2:!($6@2:=HA(7.&@-,8:C
@r284
TTNTCNCCTGANCNGNTCNCNATNCNTTCAGTGGATTTCGGATAACAGAAAGGCCGGGANATANCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATAT
+
*#(()")&*(##*("$('%"&&))(!+&!*"#*"*'"$'*)*(+&#&$!%+%#'!#***!%!'$!&$&++&'+&)!'*)'+#*+%''*"(##$+###)#"'+#"(#")+"*)&#))'
@r285
NTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCNCGAACATTCATGCTNTTATCGGGCGGAATNGGTGTGGTAAAACAACAATTTTGAATGGAATNATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACANCCTGACCCAGCAAAA
+
-'B6>&%342:,'*<9#+&(0",3)F1)=?CE!+8+010>)"@?%:3*C?7G?5,,-+<3<4$5<D'@),BE!?,9;;228698+;&)0+/3@-/.H!2H%%<+3H&/6*-&3/3)&+3;2!<;!FC*#<%.?5)&4-;@/=&17&4,CH*?%';1!"4+*&37,=/@2%F@9=)%,,13!).2><#AHD.</(96G/3"G$0+32*805,@:$-:1?$'H<F)=;A!B,DG;!@*#&?46:;E8@1F(2=0G"6B"B$148F:7G9F=B6C#$5?3;#*&*/091&
@r286
GTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGG
+
150D@(F9#'6'HD,>D"37?/8,8('=*H'!0970.55C,#E=HH;C16"A:B+4.$!,%
@r287
GGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGA
+
0:3%H8!H"%:/,1E#6!'#B%4!#!%.>67C)/;B7(+4!#?%G#:/::HDAGAG(*>-D:<;8@2$7%9B&?
@r288
ANCGCAAAAGTACCGCACCTGATNCCGGGTGNCTCACTGAACCTGCAGACGGC
+
!%#(+)!#('+'"+&+#$!')'(&&("#'#$(+'&!&+$&)#*!"*%*+)#&)
@r289
CTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGGCTGAAGAGCTAANCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAA
+
A50C%'C9B&!C+47*D""-F>*C,!?4G)#!&*A+'&A9:<!)0H?,''FG:H:'-;:=(1F'%,1<*(1%!-#H>HHH8'"*0@@)B/8%=:)1)81@H:G3=D71;C?GD@&%0@<G0?:*(.&>C23%-1;0$?:F!F8B,E-E=2(2#9@697B'!+06H($6(#<;
@r290
NATTNNTGNTANNGAATCGCATNCAANNGATTTAATCAATACAACATTTGAAGATCAAGCAGATAA
+
)!#)$&**!$*!$&")"(")'$'($(""+&$&(%*'*#&+)&%&'&')%"+(")&'&$!"+'**"+
@r291
AATATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGG
+
/55=>/A?"(!?G<F&:2'F<#1:;:0(&??F,8";+8,38B-'?=8*B&&H(7;&H=%0>("<,G,42"%444*D1<<
@r292
CGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTNGCTGCACTTTTTACCTGCGACANA
+
%+(&$"(&$$$((%)'&&*(&"$+&&&*%%'!'&&")*$*!%'"!(#)+"))$"$!"+"*(+)+)'(+)*#$'&%*$"#)&+)+*%!$'")'$%*!'$*+%'#!"*%(&)
@r293
ACCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTGCCGGCTGTCGCCGGTATTGTTCGGGTT
+
+@7@3F<(675(<D32/8+(<2E&&G**5A)&5*(..:B@H'H:"+84:&#D7C9#*@%+*!3@B$-61(:**%C2B848#C19;%H0H"-@G>.,>;3"+46E;
@r294
CAGCCGCTGATGCTTGAACCCGCATNCGCGCGGGTTTTCTTT
+
):5,=-82A@87';/3/&?2EE.!EH?5F>$B:%&@7:4->+
@r295
CCNAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTNGTGNAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCCCACG
+
,%1EC,AB"(H;>F$E!5%$42&&'/C<AG:)E#&!490>:(H:F.&:H5H$>3/?'"";&E$=D@+@04>=;$,=DCB1*,-9,1>39#2%?4#37$F#DH593*
@r296
CCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCT
+
@C91=%@://DDA"D+-(E8-.=%<8:43(-'A-@G6(%=#F;&!1*/9>4'>3C((8,
@r297
GCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGGAAACATTNGTAAATGGATTGCTCGGTTTTATTACTTTAGGCA
+
)13$D:#+1/H:-E&?72';:>686$.E#30D5H9(D5'83F9#/A3)'69;.5A"!+/E1.717),.!0B:202GF5
@r298
AAGTACGCCCACGNCTCGTTCGCACTGGCCCTTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGCCTGCAGGTTCNGTGAGTCACCCGGCATCAGGTNCGGTACTTTTGCGCCTNCCAGCCGGANCGGCGTTG
+
+B!(C:$8<C/8B&!@(B%8?63D?$5AH)'!HC9,%3@H$&>C>D%A/43F*5:7&.=-/86)178C!D-8$)B)+=H9<,#.&;51'C39.0+6<&;D;4F75"A%493G/-$1E*6D>A*G(F>57-(D/FC(1*EE/?$(BBEH7987=A/(0>:45:E@97:@B$/?FDAD$'B6A@C5?7:$68;+<>#$1@E.:=+&;/;28?$/!D+"=DH'0H@.:3$$*
@r299
AGCNANAAANATNCGTNGCCTGAACCACCAGGCTATATCTGCCAATCATTGTTGTGAGTGTCGCGATCCGATAGATGAACGAAGNCGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCAGNAACTTATCAGNAAACAGAGAGGTTCGAAG
+
''("%#(%##)*(#&!$++%)(()%$('"+%$'*%!!+''$!"&%+%'+(")"''("&&"(+""%!!$#&$"+$(%#*$%&+$**!!'(%$"*'")#'*&"$+($#'$!(#$)*$&(()"!%'$'"#+%&$#$")#%(*"")"&"%)$'+('(&!''&#("%)*&)
@r300
GCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCG
+
'=@+G8!(EC$(0>)'3G.FG!(>E62%;33G62)>+&"9'BF3E13CC+"C1@=+$
@r301
CGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGC
+
@C++!G$FB3*<12G@<,$F-%/E4)FA5"A6H$@B5H>*>8
@r302
CCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGNNGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGNGAAAAAATGCCTGGTACTTTGCCAATTATGACCCGCGTATGAAGCGTG
+
5<A?!>.5894A&3-B8.*9H)8>1G.<'C65;7:?34)?2'1%;F4DE3!1="(7C"1CF5@;9GG=#>A522G7'4)40/-&0=/@@=0E6(;-0-<-6$@9F5B683*6*04D9<?%1%';D(:879CA1-D8/A24,3&5<<HD-))/AH2F>6"G#>0=
@r303
CATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCNCGGTGCTTCGTCAGTACTCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTC
+
@9)./0D=:.C-9C94(671?9.=2'G,?%"/.C)!:9;D-?3EH4"F9(G%-'%@?#B%&B*$B;A"9AC-0,9:$/?A58F.=/F4.8,%(4@"D0+C<F7'"B%5,@3'D2?6B6(1<%@)C$+'9&1/9)<C"&BH-.D5%?=;::;C1E0266&$)',C/<+*#G/?!<H$&33.";13+-'BC!&)F$-:.)5H@AE'0?!(>D;9713/563E/G0!;/
@r304
GACCTTTAATATATCGCCAAATACAGGTAGCTTNGCTTCTACCTTCACC
+
)"2D=?FG$=/C8D-?0,FFAD4"6=6$&.3EA@1)6AG7!E)1FF!7C
@r305
CCTCATAATNACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTNAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCC
+
&,09)4#!02<&#G$"B2F'8A;4FC+%+;/G'C):7@=,B:AH=GC3&7D;E69<0@+GE!,/E<"/H,>"D!.$A:1'!%%)=!BBG1H'#;%H7D(.81C=/8.D#(.>5,7(F;>C!A=G*")%1<'"D+(C/'+-&H(7,*&>?:@)5#:)+93<EB@&'1-62(E6>9$+*!4:5760,8!&$2H69"7G%F!;?%B,#@1,8B#(G
@r306
GGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGA
+
/@4?CH,DH+H4A!,39/=@6A")9<'$8=#2/8%=/9)",);H&7<86(?9D%<2)8*F)C(,$+!4ED8F)F,A>=!
@r307
CTCAACAGCCTGCTCAGGNTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCNGTCATGGAATTA
+
"(=4@&#,D#.*G7>9;:FC,</H$1E88:'2&$$<G(@:+-72!)6:+)!.:+H&AF#!E>+2;BD+5A+H9-8+13:A@#F7)
@r308
TTTGCCATTCAGTTCAAAACCGGTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTG
+
4@0/F),3=!-)#;*/7>:,82>C8D!59,#F3A7+@B3@#%@/6D;</)*"%2:"9)H"&B6>*?H65$)D8.$''*D/'*"834A9$>0A+@G$$)9$/.3D)7).()&FA!?1@"2"=9G3@>0A
@r309
GCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGNTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATANTGCCAGCATGGCCTTTAATGAGCCGCTGATGNTTGAACCCGCCTATGCGCGGGTTTTCTTTTGT
+
+#/A/7#.;$*$5/A=?!B#?2.(</?&!)<%?4G71>)&)%@>;,H+504FE0H32A=#F"*F1D78-$H93B1(9CH=8+1(==H(H'/,<G!>('!<65@+20/B?F4,?11#%D>B;,2>!<#D?7/3>HF+!&C=$)7#7D*C&%*;GD,(669%?4A6E(3G#:?<&8<!"9$C7.0G?!?2/"4AG9(?.4
@r310
TTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCT
+
H#5E:=0C8!/&$%?2.CB@+4CE=2=6*;?>"&/A4=;G53G;@D64'@-'!%3
@r311
TAGCCTTGCTCAAATTGNAATCAGGTTTGTGCCAATACCAGTANAAACANA
+
A?(%E!$++8@6'%)C1<F?8?,4!<EF4)2$)A%.-,D?4)+:$>$5%4@
@r312
NAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCT
+
!+&*''&(*#%&#)"""(+*&**&++""($(''+$%#("*!%")&+*"+
@r313
GNTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTNCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTG
+
(#%+*!(!)%%$"(('#()+#'()")*($($++(+&*%*'!&#'!)&()#()"*!'*)*'*#%%(%&"*!"$"&$!+%!#'(""))**'$"''$'#("&&")
@r314
CCACGTATTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTAGCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGTCTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCANATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCA
+
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
@r315
TGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCAT
+
0!6A&-?89A7B=,.5CH**:0"7?&0#(*#>%"1C"G**#)(0!E;%H<!C7?.3!2
@r316
TGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCANCCATANCGGACTCCTCCTGCGA
+
-?:-/0!9-(1:.&.50F1+?&?#%#62$-E92C?)019B!G2D;0?29%='**%#:2''@+(5.&9)?.
@r317
ACGCCATTGCAAACGCAAGGATTGCCCCGATACCTTGTTCCTTTGCCGC
+
;$)=<=@?)51+>@+!;9'0<#@3+3D@?G:G9<@!+7H/<>(.'!F77
@r318
NNTNGCCACNCNTNTANCCTNTCNTCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATANGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTG
+
!"*!%)*')'#&'")"!%'&"&##+%%#)&&#$(%'*%!*!)+'%$+&'&++%#$(%+%%!(%))$!())%)+"+"+#'+)()("('#"%%+*(')!(((&"%#!$##*$*&(!+#'$'()!"+*"'!$$$)#*
@r319
NCNCCTGTTGCAGCAGGATCANCCACGGACTTTGCCCGCCTGCAA
+
"(')&(+"+")*#)$#!$&*$(#'*(""')"!$$)('(&*"'(%%
@r320
CTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGC
+
8,5-9+E69*#,3%<6'D7H)46>+F7-B%D"2-D&E#@$*:8#+9199.2'3D<8=+%A2CBH1$>FHHG)6G2*9C37!=&AAF*0++*5;A!7CB>,%<?8"'$2
@r321
TGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGNGATGTTCCTGAAAGCCGAATCATTTGAACATAACGGTGTGACNGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCA
+
,E,A)9B17"ED9B#=6E'D-D"?5*@%62"H>=@-9A)8$#*G1755(1/!.FDF298116E2=1E31A#"#&9$AFD>/5)3:;)!47,B.#4"=A'1)-B.A$'@F15!&7D8$>6*F,H9E"8'=*>/!7+A'%7)*!**A-!$*
@r322
AGTCCGCNNTCTNGNGCNNTACCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCNACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCAT
+
%)&"%(!'!&&&"(#"#"$'+%)!"$!!$&*!+#)'!'&))#"&'&(')%#)(%'%**$++))$'$"!#!+!&*)++&#($#(&#*$++&*'"%#!&('%%!"#*%(+'!')(*#'!)!*#$'&#%&#)"%%#+'&%)$!($'&$#
@r323
GCCATCGTGGATAACNGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCC
+
-7:4E4"3$62)A+1203%+(0):4*C&91$D4:.=(-D.$88$(/@&!?=%)+F);((1+A>BD,77
@r324
TGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGC
+
>@=B?@"AH?@D@50>7A6?/)/!>EB6/+5F30###"/9;+C
@r325
ACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGNCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTNATGTNTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTN
+
?+#(D$3-?3H<G/B9()<1.(/6.'0+G>)5*33.!E.*0+/655&4E+B/-/>'4+C36-)H(B;53E?C.9;):7@-:**">,%:"3;A-%6$95&96#7H!--C#;%0:G=H%7%3G-&2,@&$@;@(BE&,7?$'C3,;"62>='$$6C;4?0-5B>45)1!4F>1)B@%>6>*>%"&$B8A@G*(>0@2D"(9#G&/.(7*E)4D,)=BD<F
@r326
ACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTC
+
;%B@0/658H?."%?3(;##4H?$F*4!;%/2#,1661.A*
@r327
TAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCNTATCTGCTNGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAA
+
()F%A<2*%032"<A<7=F0&1C6+<**@.GD0%E1<<<:D"4AG4#B0)-51;&E%-=*?-$2,&0>'-!.);.EG/EB!-':%%&#!3EE>*.EH-.&+12
@r328
CTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACNGATGGAAACGCCTTATCGACATACTTAATCAGCCAGNAGTCCCAAAGANTGGATCAAACACTTATGGCTATCCAGACT
+
-G"0GC/5B;8A+(H,662,(#8'?;%B#/9$;A926("22C"4C9D;#.D0"2."2(<&:=D8F!1,E4=<%218,"#.A,<70;+#0/BGG6:B$=+",/5805E4(9G<.G468=3*1,::"H2<GA)<)4!4>,
@r329
NNAGANCTGCATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCG
+
""&&%"'&&!+"!&")"&$!*&$+(#(#*+#"$*)!+##$$!+*%'*++%%"+(%'&#"%*+#!'&(*(#"!!'!)&#+&
@r330
GNTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTNCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAA
+
1-'A,;!AE0.>6:=%/E,)D8C0>;G4D">E$%B%<GE&-),F!4G/@*9=;!G&F(?32+<:A0H-"GD$#9&0"DGE?5)<E?2>0!%:(/A7H&G/&DH'@':>55!2:?1--+E>)A@F*6#7;4FE>H0!A5$!DH81+'&.7C>$9&4F%.?
@r331
TGNCTGATGGACGCGATCTGAGNCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTGAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACNAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACC
+
@')6'4*40&,=8)'A,$"B"!@'BF#<=;(1G/+GGB6G"++:=?#)G)!%><5E2DA@6@5)D1<CD8!<F4#.>H$*@F;'8E0AC)8!%F'A0-%F3:F:3&1485D7,3()%*'88%=$;8B91,###58'(&<6623@-:1-C;%8'*$5HD:@D/DF&H<$+.=>-GD&3/1.>148/5@>.$GF<*HAC:%B1!%"E$+9/6H--'3/1<1'5#?$0";%$+'F87
@r332
CACAAGCCGGATTCGGTATGGCTGNATTCTGCGGTAAGCACGAACTCAGCCANAACGACAAACAAAAGGCTATCAACTATCT
+
G*"2$7E!$</;@)"4F"',<'/>F))$+%BF&!::63(!E*+3:5"1G$4:;9"="G5*$),CBD>"9:6*C5.+5%(&15
@r333
NATGCCGNTCCTGAATGTAATAAGCGTTNATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAGAACAGGAAAGGGGGTTAGTGA
+
&#"&+(%()(''%#&)%&&&%%*+)%%#)%"&+($&")+'()%("#*$"+*#&"#)$'#'#*!#($#&&!++!#&*)""+'!%)+'%*+%*++()%*)"&"#*&*#+'#('+
@r334
CAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGAC
+
E(1$=1;,F;B9)55757?0@0=A.>>.2>*)'>A%7;9*'':C;B;:.44!G!6'2/.&(=.38"<;A.:DD-:=+5E279#A8"
@r335
TCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAA
+
=62.)<3511.A37B7!1D?A/("!075,D+"8)&)G+*A>!)D2*
@r336
AAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGA
+
=/'C,D)":<+!-:"'$(5$G.!'%D"114+,C"7<=.!?,:5*/6F"2:"3?9?;CBA!-/>+F<D?!*91BCA*<A&$%#$AF2*CE71<;8'D*>A7;&8$=8'=?A@A,8D"9@E5F'1"C(#0"G30;:4H&=)BH&;91E//0:C1>>*+'%*>&,9<34A
@r337
TCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCG
+
B333!+@.9'-@'.4DAE@<<.-7;F;--$/(@5#'4=&+/A3-D39+
@r338
AGATAGACTTTCTCCGTGGTGAAGGGATAGNTCTCACGGAAAA
+
609(:+"*6!)#!3%;BE:>3-(D>2!465CD)F';#,$&298
@r339
GGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGAT
+
>.'&#>,/3#<'?<"D'3$)*A5G64(F=B8#3B&,24>+&'+,>9-!$/5
@r340
AAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAACATCNAGCATGCAACCTATCAAAATGGAGAGTTTTATGACNAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCANGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATAT
+
'.)<5?7<)#0=#-G*=GA=+8>%&/.2%6*/8D/'*9:'<0:2)6%-.0A?E>8*57$F+/D7363*A4GD#C0E##32D70D>D=:%<B=*F,D!2%;!-;H%?H08.D1&B#!1&AD/.H3"A.E!2";E+/$<@.D%>@<@(AB,,,(:5C='@8&=+?;,@9>76HG/FBB03F==3<!A,*5=")7'0"@@?2A<>E;D?1#(!(#B,>:61B438B,.&6(=#H'=%$3B4D1@7&9?B2=A?>E(F5&@;/*000$=G8&G@29;.GE*
@r341
ATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTAT
+
/05=*:).%=4#:C)&;D!:+E/E=B<?AB@(0AEE/)G,=(-D&>4E03&AG2
@r342
GCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTG
+
&=7''==0F=F2:("9<0?.@6')"!5!F1;E>DHC:%;"):E
@r343
ACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCAT
+
A*(%G"$$1(GH%/)&%45$F8D>HAB,!/A--<>'BE//%B!%@-.C@@54E/"!*;E?7=&H+56E3$):B1(8)A4C>,D!7,F53B
@r344
CTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGNGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCNGCATTTTGGAATAACCGACNCGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGG
+
2?*CD'=G.*%6A#'./(.#<7>H?A@,:$,E89#)CA2>C785'8$/3"3B7!4+*@(>G0?65"8(7#+0&63(A>4&/D*4(C7B"H6:(:6:@'($:.+>-2ECE32(D8>:=E4-?=9H8-9E>5+**B0C-EG-6</$97":>6;?A%=AB?2AF&:;G,"+.+;E.'B<9C249=E#;+=%==?5')5>-77<0-(-.)65GB.G0.1A3?"&E>")728732>A@DD7DD%B=F;A4440!D*@38?
@r345
TGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAAT
+
CD:"205&G8"$)F)&D#%H&F?%3$(&:"5))B%,*<%40E6;E?'$%)8FHG3.E#,$3)62-A7%8=DG3)/,:'?#@%:
@r346
GTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGCACNGTATCAGTCATTTCTCGCACATTGCAGNATGGGGATTTGTCTTCAGTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATATCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTNTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGGATGTCGTTTCAGCTAAACGGTATCAGC
+
:.=C==7"D-23!%)DG!A:.*E#C3@8@<.2E0-E*/<+6<@"<;@$#HC/6<+F/G(A3.D>$5%E=-BAF!$>,GG"'D00>*;DE+3"7=3=973D@:$BH#='"G!<,3*"?<!*G;#A&8BA?:/,/193/G3*"83@-%@GA1,.9.4$'GCF4'*-5$">D>9AC-?>7;>"$8&?A!,940&'/A;&:@9*C)(-,H<3$5*C&*<7<#8<@G;>!E*)3/1%0-,10/!86;/%'>+H&-@)5!':>H512+*:4CHE<!B61DF0(&8-1:!"D<,*/D$#!38)&9"5>92G%<9BH;?F'HF@=H2=>?:!.E3"6B!<@H<$-;16!
@r347
TNTTCTCGGGCATAAGTCGGACACCANGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGNTAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTNGTATAAAAAAGCTGA
+
)'*'&++)*(+$#'$)+)'&"+''&)%*(#*!%#&!'%%((&++!))('$''("*&"%+)#(%&)##'"*"$&$#!'*#!&%!)!###'"$%'')$*"$&%)#+#)**!"#&'#($'&##%&)"&$''%)#&+%#$!+&#""$)#$'+(&%)*&%'$$+%%(%)+())')+()*'*
@r348
GCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGAT
+
/)@<4H2H#0#EEG8:<#>*53:;FHCH1-.9!+"=#>9C6FC/#*!@5'4&%&#&@?E,5?6A7A7?5505!$D,),?
@r349
NTNCNNCGNTGNNNCNCGCAGCAATGGTTGTGTTCTGCCATGCGCTCCTGAAACTCAACAT
+
%)")"'$"$'*!!&#!+)"+*("%!))&)'&&&$%+!$"(%*+&*$(%#&""+#$$$+""+
@r350
TCAATTTCTATTGATGCTTGCCAGTCGTAATCANTGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACANTGGAGGGCAAAGAAGATTTCCAATAATNAGAA
+
6(7)296CC8!5?:*F*/6/56%:-$HC%A)-EH;'-7C+=")A(?'-32@%C+'7AG3"*B6<&73+4C9!F*!;1F(+<20+3G:9D:,&!!>56061FB13A"C=;;A60$"C6BF&:%F?+((=+
@r351
NTCACGGANCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATG
+
))$#**(+)*&*%&'!((!'+(!!'('"#"*$*+()!+*$%!$$"%#))%!('%$!+'$+##%"$)(&")#(#%%*$!()#"$)+"#$!*$('%&#%+)&!#%*)($'"#&"&+%(!)$"%")#%$*
@r352
ACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCG
+
<3?22#)E8C+;(94481?2=&$7$D)?C@G),!AD23$;=&<<F42DE7.?$5+1H?/+H/@;->C?EEA%:A&!)G:@2'$-<6$=55+@H)<!?>"*31>%!4.$1&+'
@r353
AGTGCGNGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTT
+
(133;"&!*G?$>?8(7+/*$!.BB==89&2-!4GH9%-?'/@A@G2'.<5,,+7
@r354
GCCNNACTNACTNTTGAAGCCGCCNGAAAGAAGGCTGAGCAGCAGACTCAACAGGACA
+
&%*'$'*"%#)!$#&+)+%&"*$+$!%(#)(**&&$'&#)#"*$*%*&)(*"&)$(""
@r355
CCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCC
+
G"DC7"54B*G!B@DG.*#5"/?77B&(.D"@9?24C'%4G/;&D8>0DB5+!>3
@r356
ATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACANCACCANAAAAGGAANTGCGGCAATGCTCAATGGATACATAGACGAG
+
;,3D@=(1:3C?-"32&.H,!.G3%$'"-"CDG=G%@B7@(=E@3/1$2&B@9E24#E.<;<642<C@:0/5A:;+7),G"+(,4"../""E$%@7&F(,*'?-6").E6(=>#"48>D#79'07&.7:
@r357
GGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAAC
+
@'/,:$,5)81-)E1!FG2B%,E';#/,(6'+4/%3E3!*<:/;C%6H6C90?H>
@r358
GCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTNCAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGANAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGG
+
?-2H+E*B.(147?A:7)230+'D8,.@7&')F?<2&&+760F!/<%.18+/G-.8)-<%@**$4B5)(0?-0:)'E<37/@"-6@9?EBD;.38-,&D/0>)B=2.E"A/HF+,-+D,2D!D!))DH
@r359
CCCGCCGCATTCTGNCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGNCACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTNCTGAACACACCAGTGTAAGGGNTGTTTATGACGAGCAAAGAAACCTTTACTCATCCCTTACCAGCCGCAGGGCAACAGTGA
+
)+&+)!##$&!!$$(#)!+&''*((($#&*(")+%%**+'%!#"##"(*$)#%&**#(%''&+'%+*$+*%%$*)%)!*%&#$*'*'#)$!!!"%##'"$(#&%$$(("()%"(%)&$#&%%'")!+$)'+&()&*)!)+$!#&*&#$+$%$++!'*+$**"$%&'"&''+"$*(()+#)(%$#"#%'#'+%*%!"*$$&"&&"%*"*((+#
@r360
NTGNGGTTNATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGCC
+
&H2E:,5%,<%D*F&/)E&GD=-#0$5'8@"0)>2G3H.)3/)H,>'7*=ECH4&D7'2(H!>5F9,9*-/
@r361
TGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTAT
+
23)9B9&#>'#((%':9;$9,+<H*<9!7"?!'+1-!C7;EE+BGE;HC%C$(*H:*7C*#&9*<#')DE#AD.#)<;G><7$:1,+#A8//+-=?60A@!H
@r362
TGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTNATAATCGATGCACA
+
E*7G#-7,8('&D("%;%,9!@@>@'&==/5+?:A:0D;6#&(H#!>/"'/3*43G<41@E7G.:$#-":#:,*+8DF&6H.@32G6H<5A
@r363
GCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGG
+
**'+#(%()%*$"!!!!*"$(%(*!"%#+#$$+)*$'&+&
@r364
CGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGTGACG
+
5D24>(<40;6(1#C?2;,&)5:%0.1&@*3%E>=G38#%D%?904%G9'8GAE'"#772#G/8
@r365
AACGTCGATGACATNTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGAC
+
@"(H6B6G-EH<.8&68E$(4@11&F"F;@+7FG<:*=6035F/8F=23*E#1B>#GH6")$*A'E2432$?!4
@r366
TCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCNCCGTACCAAGATAACGCGTGC
+
-FE1&940*?@&6,/+.&01:<</?DH-9+!106C:D0'04#$>*.-+5:-=)H4:6(%!7:F*9=B!#
@r367
TTNNNCNNACNGCNNAAANCGTAGAAAGNAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACC
+
&*&#(!#&&()(!(#&$&)'#!%($)&$%++%$$'%!"#&%!+!+*+&!%%#(&#(+!%+'++$%)&#("'"'#"&+!)"(!)!')%$%$$!(&*&##"!"*(("*+$*(#&+%*+$%%"*%+#*&*)'%"&"'"%&&"#)('"(+%+('*$++*"(%)("+($&*'#$)%(&*+$"+)%!+(")!&!()&#&"*(&%&($%!%#!+#!"%(!"#$!")!
@r368
NAACTTAAGATTCGNAAACNCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAA
+
!5(5B,("C/27<*;@!9FB0:+H>;.C0!4,9&).GH31(,9EE4,H2(2>"<+%G&8!*:,
@r369
GGTNNNNCAANCCGGAACGATACCGANGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACNGTCAGCCTGTAGTNCCCCA
+
*$%!#&#+#(%'&$+'&'#))!*#"!#*(''#$!#*)!*))###(*+#&#)#%&$$)'((!$'#"++*+))'%+$*+#($)#&''$"*
@r370
CAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTC
+
)C38=5&1/:6B<-A8;D;%G)E2!/>G&H:$..GCD'/"(;&;8)=9"9&:6#/18B+%49E=/!&;44)!&5*-8E<(&7?377
@r371
GATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATAT
+
*%;*-%.**(/C0A&<,.'"4G@;?2",;A0;>*+=*!8?-%.7,?>/83'<2A@C0!'11;.7,=#*#B9!.'HF=+%G<"@H4D:&8(@64H'(0229A<B)@B.9B0@?5<<93+>.9G,*F=H'3D,+?7!96+6;/6<?:7:9#>1.<E<'34@9;G'=9;=6CE>):
@r372
TTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCG
+
2A>B(9;7(@*+B#:1-.!8E>35501<.E013#AHD&;)/H#!00
@r373
GAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCA
+
30-)G<$;/"/EFF>7H-G)$6@9;71$H7=B)(C%5!D%#.-$%!;692@G33,=CD"@&BC9'-(A47<"(5-2+H(33'0-=E
@r374
ATTTACTGGGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCA
+
;A1")4?65:(G.#3;?DDG!@3=F"&##$+8$/>$CGA79>4&A(<*("/#.5)H/7A,D%+-743-H@GE"+*2,
@r375
CCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCA
+
74H!0/6A<=D#8+7+%?4%9)@%9+%;?<3AAC,(#)'?BH#6%#A.A.3,A:B5&9D6CC/1D1,>#=*@<(57#0@7,F?H)4F)E/'9;0G@)DCG%:H7@7/37*$*+@+344#F<))@C=*;G
@r376
ATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAT
+
(=!:8(<&48G&5&98C514!$(GD6'=+F%;@0H!%/.'$5>H7*58
@r377
AGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTANCTCTTCCAGCGAGAACTTATANCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGA
+
/9!8/-FH3*/C+#2?+18$D>/6(#*."A!6F!=&8GG"E,$?C*89)-+5H;3DD="<@2@"+;7!!7,0#0#0"&$57262,5%3+/D7C50;&5#*<@9-/&@GBG2;877(0'AG'/)%,9##&,."#>.')*@A/GE746"3<5!5CB9H30+B)>.:(0/.%;4,4<0?,4;<.#'1
@r378
TCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGA
+
/*-7>*)=)@$@&0$)6C,C?7%E%!*;3..;6%$&!6;>'42=92>;5""1'&."(<*15,52.!"'B2>=/E8%$6+CEH:7$&<C<)?*<6'-&6-
@r379
ATCCTCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTAGTGGTTCACACGGACACAC
+
((#(#)%+%')#(#%#$"!"%*!&"'&#)'(+#%""%"*$(#"()&*(+%'*""$&%&%"(+%#&++%%'%!&$(%%*"'$)#()#"('&#
@r380
TACAGCCTGACTGCCCAGGAGGCACTCGCGACGCNGGCATTATCCGGTGATGATGACGGA
+
!.:='0>9.58$''F(6=H&G%3E<"57=;:5H78DFC<>!)()+!EB+,&;-H&/HE/2
@r381
TTCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAANC
+
!+%$!$*#)+*('+#+&')*+))'("&$$"%!&!'%+')#+$("!*)")$(()$#*#%"&&#($*"&++"'%)&+')(&(()+#
@r382
NATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATNATCTGACACTACAGACTCTGGCATCGCTGTGAAGAC
+
%0#,=E+207#C><C(:'.:H5#>83FD/+:=0#<(+@2'B--7F#>*"7@HHC4"5$+?A8<@<!D>*8!8H&++-/=:47@0G-=;8?CGD);2HD&-9!5/456.?*+4<'E61&G!G8,+))8B$H''D!B*73B?+(2D-0?2@)5>(F3,D0F?D:5C@@D8+!8B?-93;7AH/BG</,/7")8<6
@r383
TCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGNTTGCTGCACNATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGA
+
<5!D68@-D(3>>9>9?E;.D)$448?C,;71$+?"(7B8)+?&9.6!<221(.E$@.H'E;880<C6=G9$6?/#4=-#=+A(C;&"+.8B+0$,#3"416@4+$
@r384
ATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGNGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTNCACATCCATGCTGTAACGCNCGGCTTCATCCNGAT
+
1)-<$$*#.@6>2A.4B.'%-CGG5?H'2?*12B4&8./;/9;7?C@638B/):43!E:0-;&A#2;4/4*:@&2C<2F@7C71F!/AB:.(8;G3@:6EEA(*4"#C9088;B"5!&&G*-+=<6H68DH29%<#81$>FF,(>/AAF>&1<,CC=?E%*=C2;C-8CD+-G01*,6>GCH.&,F$-,&C:805%C;:'1&
@r385
GATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTNCCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGNGACGAAGTATCACCGACATAATCTTCGAAAACTGCAAATACCTTCCAANGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGNTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGA
+
7>))1C9!9&"H*),(32G$;85".(9,55%>AG<19:7$:F41,)AB-$,D++FC%7:)B=5!#7<-H9B-4;!FH)-2(F+9H.G@;=B7#74&C@A$?39'3*,H"06/&28@5A;C2%-65:)8?A42=GB,97,ABE+;&=-+H6"4@;.>H#3((GC&>)9.;)54=!8C*#H;E:HC%83.<$ECB')9$6DH/B$D3A>'FF.H&1"F9'),"*;+4&&8&3*2>*6G$*#&B$'<*H'*!4.39,=E*B(?=*#":")%2A1G4HA@%22H#H9A>@2+.B/9@178""=D1
@r386
NNTCANATTGGGGGATTGNTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGC
+
%''''#%(*+*+%%#)""+)$!!("'!#!#")*$%%(&$!&()%$#!#+$(!$*""+*)&+!$+!!$##('!%*#**"#+'&!&('("$#$!"&*%*
@r387
TGAGCGAGGAGCGGAAGTTAACACTTATGAANAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAA
+
.C+2%>##*1.:8&-D?H,0B%DB+.4(%'+C&D'0=E,F-A'&D$%=3C69>H+*&.B*3?%@E;:H#$=+F!%5>449**&/GA992?>)<<-817:*
@r388
AACGAATACTTTTTATATGAGGAGGGCTGTTTTTACNAAAACCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACANTCATAGATGGTCGGT
+
<9;4F;<'(H-"07+D..))":8<%$2G)HE<!HH9/&?B"3=,,F3%BGH6=>339FF&D%F>D<2"#@AD/G9B$D""4!!EB2!1H@+,-$5(*75*=#D#2#&5@/26&"G!5@6&75B=D:FC=B$F8&<B=%@1+//6H&783GB6!7%'B/!66A/?%6E1$4)93
@r389
AGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTACTTTAAATAAAAACATTAAG
+
-AB$(!"+&&!$B@5>,F"'.B-%5A=:.,/",*(-,A-+!>;8G18&'G#!?>%;:!14>ED7/
@r390
AGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTTAACGAAACTGAAACAAGCGATCG
+
B4(>-**$%,,4**>+;-#";1>)2GG7CD@$8<.%>')HB@.!.C"875C<'@*D:&;!H&5
@r391
NTACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCT
+
-A89+5C5*6,+:5C.7-'+6DF$7HCC!0*/79+;>/F&:H>5&5-D+E8G8@=6A)1B
@r392
AGCACACGCGATGGATACGCGACAGCNAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGNATCAGGACGTAGCCAGACGGAAGGATATCTGATGGCNACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTANTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACG
+
;#&/H"90'H1%32/.@+?@0**B...@A6795:<:=F9>8$$?1'=.8%AB&#(0=)09DB;3@-75,;1H>4,9"7#77E#-A>#1,F#3)A0<.3;FE00@"&5(*(33A7)$0@B,3:,H$,9:<-)26?)G98!"!.$2.97D/66.5=@BG&9)<F:0?=>+8+(E9@C1"*F#.**-(AG<B%4=B-57:5#/8(6+'5>>3BF?38
@r393
AAACTACGTTCCCTTCACCAAATGCTGTGATGACCATTTC
+
3,G:G-7!/4+$&)?8;>890A(9%=C4?8H+17@,G!FB
@r394
CAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATGACCATCCGTCGGCAACCAGATAAGGGTGT
+
-=%.7#FGC>A92$9=?2C(.@G73/"7?>=-$<92?*@:A=/4?7+-&<<-;8A7-(911D!?.F?>>,C$;G1A7.1@-#.-;/4&2
@r395
TCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCNTTGCAGNAGATTAAGGAGCGTGGCGCTTTACCTATGAT
+
;<*;>%(15F#<8!0?(%%@>B2$69#;$26A*'A<*&D3%D5"G7.!(34"*>&2H>'A+)B>/*-/#35A'$-)2@>8739B2F,(%;C!6C7G@"1E$6):2''3%"'.:<C(1)H0@6./E&<!,7.,(#+3./#/8&69#A*<(8*<'G@5:=4@C=5'6B
@r396
AAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATG
+
<*003.&6>D=-!/4=,EAH.C/-6D0G#HA>C1:47G1"6H/?"9E<DH:6E4C&7&7%<;;FFEA4HA?9)!.1E(H&8-"G>0)3:DFAF'-H*#?"45!8HA='+
@r397
AGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAACGATCGCCCGCAG
+
E@F3+.5%)5"(0=(%0?8',&D."@%%0C<1C8/*G8/6?4$,<B+%8F2A.6=/#%E49
@r398
NTNCCGTGGCTGGGTCAGCAGTATCGGTAAGGNGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGNCCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGANCACCACGCTGACCGTGGCCATCCAGNCGGAGGGCGT
+
"*!+'**!(#*!"%&$'!')%('*"!!%""#%!"%%''#)+!&+*%*(##(*+#()*##()&)*#(!+"))!'#"!)%"#+$+)+)*+"#('&%)#!)+++&%'%$%(+%'%*$)*!(')()+%(%#$"$$$#*&('()%")&(&&(&'*&+(+'#*!"%)&"$%'!#(&!(++**!*'%'$%+#%#")%+#*(#%!%#"(&)"$'!)+!"!#
@r399
TATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCA
+
=%?49#C>6:F)0'38?63-$@'B"'F6C4>7,2(4-#HH-@7B)<!,+#;E)1-"@805)E#%A=<
@r400
GAACGACAAACAAAAGGCTATCAACTATCTGATGCNATTTGCACACAAGGTATCGGGGAAATACCGTGGT
+
,!%9@#GAG3FEEFBD+7!"A'EC0H$%-(301>1468=-G;FG0'/@04*8FF>H/->-%H>H1!&.E!
@r401
CCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTNGATGTACACAACCGCCCAACTNCTGGCGGCAAATNAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACANGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGT
+
>87D0H5:$'7EED*DH%!<*GBA#+H04:G;D-%3/B!:./&<)62;D.GG-7&=&79?2E'5<++41E68:DG+?)(+1E$**<@4*+6@15#C86#%,/B8.EH92&)*+5*(;>/+2E0-1+'9A"*B$=$"F<HE%=-(,=B=.6FB>;$>/'"#1">H$)7%D)45.B4/0D+E80("7"5A6#+8+F/1F4@0(!0A86BD3@''47A$95H$7#/EH/1=E-FD3>40+A1FB7:)!(>?
@r402
TGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGG
+
$$)E80&E;4+)+*:8-C.78:6DE-0).9?%FH%C94ABHB$;'!-#DFE$)-/9*!>!
@r403
TGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACC
+
0'7.G(,HD!BB-;2.'.,'2+D682@39,1$=4CF>0.#=(A'FC'8
@r404
TGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACNCCGCATCCGTCAGGCTGCTGATCCCAAG
+
+3904.'7?='6*8,4,7#;B;DF5CA7<84>"709H%;,%9B?'@9=9@,$F+9.&8=::@F@'H+=.8A*7FAD<!?&"+2+$D8>-(06$:0<C8#64;B(
@r405
TCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCC
+
>G6H'41D5A"-:&)4<+G>HF(".9,B<:8D$68$9C#**5<0H4A"!&"6B1%$H5<4>.#*">F?':./G.E<H=/CA$5":83&"*:E?6-,G;.
@r406
TTGCAGGCGNGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACNCNGCCGANGGTGGGGGCCACCTCGC
+
7160-G'4/-AG-(>E2A/9+%@.CF!!A&B2A2=(0(E+)2/A3=:93(64B,)/-/D"'+!=2>AADCE+)0C;6(14/5'D"AFAH9<&5@*$B?"G.&A,-G+E5E'3$:3,*4?"#?8H@=C7/#%0(,&
@r407
TCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGG
+
*3)D'$9:A>:$H.#B)F,C$2::61!!=C<<')F=6#DH>):F07%A5!A$/9?32:@2$FB-;@(7D//.-2&B@B?B)@8*7=,A$:>E#H&%'A@:8@,:;&)*.5>G"/CHB"%%=<-G;CCE8'>)4+4FG9D&&0'"?)9H.7C-'0
@r408
CCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCGGCTTGCGGTAGGCAT
+
'G/-F?2%<06EA:!(3AC91(8D=A.?+'H#3D+3H4"&E;F18!=9:@<*23*AH&-+#G'94$C5E"$1><CA*H$A;4E4E
@r409
AGCNATAATTGCAACTCATNCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGANGCAATAAATATTATCCGTCCGGATATTGAGACA
+
$F4H?76/B9E)&':.(2%42=&">7$@'F0H!B,%59F@>@)=D2$3(F9C3G4>"(DGH<C+1>E.;5,"33(:903E=CBGA492C87@.C6&*67.56(;1.)&E(5EB"5
@r410
CCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGC
+
1;#1E3!=559HF'F*+<3%5)=!D2&/FF(!:?761**/F4C#!:B<'"$1D(F38(%?8*-@@E+G#3%<#.(($
@r411
GATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGNGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCNAGCTCAACAAAACTAAG
+
F-28%$8AF"#E0../%.0E#!=DF:7D%$8@AC&(,"<(-3"C'D)-03-B%'B/C5(;8A4(*!?.DDF(3,;@4+--F%H*A,78943B96A3,02"B(#6H5'=0,/E:,%0(=3':C"2+2:DBG!<HH;HFA4+(1#?)B16$;4,-7!0B8<07+AH$>E!<E<65*.F0.<2/@.6@H&#C=<@:A:2$668@B,4)66916EE!2E<-<.8>%,??C3=3:!/(,B.EH:,7+?+23>6G6;7#<C6A749(5(%!8;?G&-""#%;6?5@0?<?13?!8)=B9)#0$$:"BHE>H.%>%.;!/7FE%(1D;)'2E"!5!!"B8)6'?H'>E"H6&6(7
@r412
GCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCNCAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGAC
+
="213@D.7#%EG:G1,>%G-HF)B2,#18=.E:'.=H@(@7B8,+9D6'*!='D?G-C,=*'@E!@AC288A*789<@&8F06B'@E@D$(),,?+;+$D>B&G/2F=21D85.#'.:>.?4-?58H8FCD<E,,F8GH86*(E."/F04%!%:G+
@r413
AANTGTACGCCACTGTCCCTAGGACTGCTATNTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGT
+
"%'%%+')'*'+'*&$'"'&)#)$(*+$&**!&++"%"#$(+(!#'#%%*"%#"#(()&%$&''&'&)'#%!()#%*(*%#'!"&)+#(#*!*((#*"#%$()#))++"'$$(+$#)()()'"$'$
@r414
TCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTC
+
$D@)039%F/:A?&2>%!/#&6)A4GD:=51:E,5-4D@DD"0)5=(H7;;('BC+<?=,!;)=%H5@GF,5F3"E4H;!%8+//$2A."$8"$>96*G
@r415
AGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGC
+
FED%7%E%21$E!BB0&8E;*6$0#C3",.1"=(??.BF0/:4*
@r416
GGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGT
+
'9<7*#00-G9#DB-58A1'.G8#=>(,#6&1/5,H$?DD2<$05!+>E953(&@%;1C%:.9")!'-HCH9!-!-50FDG3+<FB65DH%>790*H'&!$5$*&+B2!/-1E61D/$'&$5DD9=>)?&0?.,,C>#8""GB>;2G?$&F08F(@@0+.
@r417
CACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAG
+
32>G;!?EEB+C*G/=60"/(%A@"@:>$*@GC%:@)AA:'*>!;-CDD'E=&>";#.)@5@5-.G3=43',;&>:B6*!G9716F-6G@A:!")"(H
@r418
NAACAGATATTNAAGGGGAGCTTTTTGACTCATNGGATATAG
+
+)+%)(%$+&+!$*#"*"&$%$&"&)&%#!"'+(!%)*"+&$
@r419
NACTTCCGAGTCAGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTG
+
"6#G=B("9C)2(2A#D=+"8#)#3*#D,)!3?>H6E&EH#9G<'<5D>3..G:B/0=B*#32A
@r420
TNTNNNNNTCTTCACNAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCNCGGNTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCCGGCGTCCGGGANGTTTGAGCAGAATAACCATGT
+
*##"!$"$(#%*("%!++"'))!"&$!)#&!($+!')!&"+%#&**"%$")#%%&+(!%&$#!%#$)'$*)&#(!$'"'#""%''*!%+)!%#+!&#*!""$(*')+$#)*'%(+(*%&"%#+"!&&(%'+)&!'!!%'$$$'*#+%$&(##!&*&$*$
@r421
GTCAGGTNCGATGAANCGTCATTGTATTCCCGGATTAACNATGTNCAC
+
'%+)+"!#$&''$"')#+%(()'#'!'$+(*))!!%("!&*("'"&$&
@r422
CTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTNNGGAGATCAAGACTTACGGCTNACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACC
+
F$H6;BD+=2C<H'$A@1/5&92)2(.)16C>#58A;3C(40<)ABC-/1-:<.F@94)%2&7!.C/40$(!+(#++<")7("7FA#%*+DH'160#">%!;C@:D?4D,G.01%?>7D23//H2DA,0E9+C!9#1D5($=559:6>-
@r423
ACGTTAAATCTATCACCGCGAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGC
+
A1.E2+9>9%F!6D627A2.'1=2>>&?72#,4G68*-'=H#DE6A)(1B+(7@("9'22'=E%?BF?<);'D?'@!G7CEF@HG5(/D*/=&G'E08!3#6=0H?&9$);-
@r424
TAANATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCNTTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGC
+
198;&,,%'>!3,5*E5FB7H@;*,?@.->9B.,#;++6*?4!34>)C6.2,:84574+'BG&/!*#$'*<C(5(=AC:<<AA:-GD8<;C%F7%G2=569"3%8D=@7B1H15,4H==)*F,3D/E)AF0A"'?/+",+H&64"(
@r425
NCACCCANAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCAGATTTGATAGTCTGGCG
+
$$@+&&</(68EC2!H$:E@;':&B3C:>+6@/6#>*A+7"&&3@@*:,;&+C'+:E$B!1<C!@6E-D0B,595A,#(80+.0*:7*7B=3BE8*7#86D2-
@r426
GCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCC
+
+%&*FF:"?*(>?(&/)7&3&?@="A.A3FF!B96!B6E:9/):''9:&G2D6>*G2>66)CC($@9C>6;4F"&$<8!40
@r427
AGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCTGCACCGTCTCAGAGCCGGAGGATTCAANTCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACA
+
7/>,97%*)C+G6$2(!33;(4,>H?A.<@5*.=-2H"8H:"03*5"+<8E&G.)/D2)879+63632';%F>5B:#3A2"@,10=0!&>"*&E/$6#'(#%(A$#?-#&.%20A$=*?>*2;4?>>>$;.&.4&5)E9,)0B94=%B/'*+
@r428
ATATTCCGCCATATACCGGTCTGCCTGCAAACANTACCGATATTGCACCGCCAGATATTCCGG
+
)&$%+#$'##&+)*+)'&&)$"'))**$"((&%$)&*"""%"#'""&(#"%#!)+)(%*#+"!
@r429
NTTAANGGTGACGCATATATTCCGCCNCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCC
+
%")"(+'!(**)+())#)&!*)%&#"(#+(#"+%&!%'!(&%#%!)(!+!'('&%$$&!#&+!#%"*!!"(&''*$$
@r430
NCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTCCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATC
+
!E@.-0*(<*>8E+6%@+F8'HH!#EE>4D6?D!GGEB@$3=>5,%D6A7)1&3"2%4$3/,7%=<<4.;409%EECG-BE=70?.$-B=;$H'(<.8
@r431
NCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCG
+
!C+.-+$5FD!((!77,B30G>@<A?)C3@F$,;<--:)#-%'1AC**3>B0#E)$=%,=,!7"G7-:B$%D<<
@r432
CCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTNAGTCTGCTGAACCGGCGCGAGGCTG
+
+@B.G&4$F.;.(!+(:",>5#E8*.!55GC84@2"%+0*?6B->@@54?8:''<.B":E<*/-:$2//A<G%;:
@r433
GCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCACAGATATGGCTGCAACGGTCGANTGCCTGACGGATATCACCACGATCAATCAT
+
*+"$%!+&%('#%!)#%*'+($)+"()'+$!)%+)&""%)#&*$+$*)!%%#)!$!#*$#&&+'$&'$%"!""!!(())("*"'%**+)%&%)%#"#!')$#+*$+&$&$%%$+&&&(++'&%"(*#&
@r434
CTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGG
+
,14=)4G,-=,D#<+;:-/)-7$*5*@9-,#;%H<>40/:@5!/79*?+'@19;5%
@r435
CCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGNAATACACACATTACGCATCGTTCACCTCTCACTGTTTT
+
<>DCA)/GADH()62=:*&F;(,A77:8)"!6G60E>&D&?)H()G'?0D7,/>)&20;@B"83A"5;/%CF5=9<2>!H2#2<,0&*=)!6:*D*&-A=FE++?4=13%?>#2H"7
@r436
TGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGC
+
A?G<="2%!!8:.D.2:()((E@0E*D(22#>3241F3<F%3*=)77(!*?!670+%>/3/805$H,/$7F*D09+),'&D$AA64D=?&H/'1@(,C($C-/<$4?C0<$E8!B<#5B"9+CE'%9!CH*=B<=-?67H#(($<2;A&-GH>87&;46$05)@*A2+>5&EC98F-"5"#.:8CB(2*(2)E/1-0!0G
@r437
ANTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACC
+
*"//<<'HG,5&76*8;&2D&7*G@1+;91AA26H=$#,&FE@:->96A@3,(EB=0-3C/:6EB+0>"9E&!>"6DE5
@r438
GCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTC
+
9@&5*9:F@$6%G)(A(F#0>8E4E23H-!39&41-;.;CC&<.+?*7.*0CE")
@r439
CTTTATGACTCTGCCGNCGTCATAAAATGGTATGCCGAAAGGGACGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGATCGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTNAAGAATGCNAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCG
+
.C>11(D#$7*>E'=A;"!(2*G=(<*AE=C5=:1%$!04@*F-4"%BG,.1--E;H.1F,'=B!C'CHGD?'?F'4,D#@G+A41/E$7-%4-$&&(//C()A<2'B<)?3;H0E:.3D52DD:$03!*8-D33E(:=,$4/"&6!@9)B%<!>$!F8H'4>&@7F7<)13=)FG@@?E$#.-GHFC,4.B8'%4-?!?&$:2+0395?-'06=#,&-##FD,,"+.*-;0:&C:A1C6E7,4+)(
@r440
CTCCACGAATGCCGATTTGCCAACGGTGTTCACCCTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTAATATCCGCAATCNGCTTTTCCGAGAACCAGAACTCAAACTGTA
+
+!''&'!%!*!#')&+"*#*!)')&$%))'"$$%)"*)#"%"*+!!&#%)')'"(#&)!#*!)!)+"%#*)$(("""#%(!!#!!)("#(+&)$"$**"$!+'')'*!&"#)+(##+%#+&##+)"')(!*%%)$*"&+*+&%"$%"("#'"((&(!'%')&""$&$&&)!##!)(()!%#&*'
@r441
CGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGT
+
9GG53$F;<)/79FD#=+48#,C=3'$E(6*D<,,1).H?A=C$H=/AC:F7E:84FFF(D#+77C+6%C)3D%$"1D
@r442
TTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAANCACCACAACCT
+
**B9FB;1;>A==?'%7/-=="$+%-0.3.7G0B6?=A%C73C*'C'GD->78E8.9AH&5EA*,'=&?!</!%2CC9).6;$@9"3AE81-?G@6*96!BE$
@r443
CATCCACCTTTGCTCTCTGCTTTTTGACGAACATTAAGCG
+
/39C/#-;>!8C"C=9E>D%$B*-?9.9D@3;(4HF2'<9
@r444
AGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGT
+
/C7?D*AB52&=&2>)H)FA7)*:>:&E417:*(D!"@:@2<!*2&0$*!@@<;33/#3A(<H8A8-8@G
@r445
AACCCCGTTTTTGTTTCGCTTACGNGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGNGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATAAGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTAT
+
.0<*1G0""A8=(%69)D?.'1@:75G./##+CF#B@1C&>6,&2-+D.='7(73*3)5;0;A=HA,>!30?@>?A+<89'#,3%2%:?A<&;<<F.G@>#<9(8H&2@:6(2-;;<$:&23A/.H@E=9C)"@=F<2?3D@3<271=1:@<C;3$5)*0F.8%C1+-##,(8CBF&!@1=HE-BC038320:F#""
@r446
CAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTCANCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGT
+
:(?17A#1A0,B0+4:*'C!?68())EB>A2'D1,H>0.<.#*6E)=<C'+F;*75EC!DH,+C50AG*/C;4'1!@25)-1;%%>E2<?$(7?<-/6('@:(&:/)'D'++!0-'79,224>$3...DE!61D$=%+'(%8@5.+%!(
@r447
AAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCAT
+
E&*?$<31"D.4EDC>*'"@+'3)52:G3A(<&;0-@?,$@15B&@-6+725)<%+<(*,7!-'3:8:..$B):&E682?1-/B5*FEH=;GF5$%H0$CH!0',G/G1,
@r448
CAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGNCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAG
+
.4'7!0/2C7>9(":8@1H(A)".!2.).+E0&!4=@(@>"!'>,+8.>(&?,@@C5<'@"6C;1/:5D#9@G4"&!.G3,6!>3,#4$-5:H3.=5*<@HH;D6);4H>;C*H"!B$@$>/H
@r449
CCCTGAACCAGTAAAACAACTTCCTGTCATGNGCGGTAGACGTCTAAATCGTGCACAGGCTC
+
7(D#&;AC7#,"3//B6-3+-C@0():0<A0;5,$BC=0B:,&:=&!#G;9!9!!%(@),/F
@r450
CGCGTGACCCCACGCGCATTTCACCGTACAGANCAGACAGAACATT
+
(.+%-!AA$-/C95#5AD29?:)9?"(%@3*770);E!:;+AE@B&
@r451
NTGTNTTTGNTTTTGGNATGNNCANTNGNANNCCCTGAANTGNAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCNGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGT
+
'$%*"***$"$$")##"#&#%$#($*!&&&&$"(%#!$*!"'!)++*%$%)!%%*&&)%&!(!"#&%'+*)#$+&)*$&#+#)##+)"($('+('"(*%&!)$'!('!&()&+))'&)"$+$)$)%"!"!%'+(*%)$#'+*#&*#'%$)+'*+$!*#$()!%*()("$"&$
@r452
GACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCNACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCNCTGGTCTGGT
+
3?%!(9(33;CE,4,.7()*9A"?'0+<#8("+5*D881C052*&-50$!71381;#>E0*,G$#$0%$-,!?12-D4=.*H"9F$$:+(D&%<,@%"B@;)1"=E6:);84C%/.D'@<;B:*4*G%5(A1BD!5;):8=+?>'CE0H3>*18,'>""BG5!
@r453
GATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGNGGGTACATGGGAACGTCAGCCACCATTACATCCGCTG
+
)$(=!<2#(16HF)G?+H&18--7<+;E;9+BCD<&354EA<:&-"+?+%D)7?/@8:37%B<.AH@B>32?191D.4'?@AB@56H7#1&
@r454
GTGTCCGGAAAAGCCGCGACGAACTGGTATCTCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGNCAATGCAGCAGCAGTTATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGNGGGAANAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATANCCGTTATTGCGTACCGGATCGTCTGCGCGG
+
;?AB@B8.GCC%D<')*H@?G<F;H-:?=2<C.;",$,2*="HFH/1A=$='++7@H:=:'9/D,HF=FGEE!82"%!B/+05?3(59>'850C%#1F8)=9@*2236+=,C=(%,!H<?*A)$-,?:AH1!6.#;8"$,,?;?-7;!@2$08,!%=DH<98,#&-06*#:)6F41:1D/+E.#=$1294:7/5=7%=-D!"$@?&@9'.$9:'+*(#E*$,@8@7*)-3:186*-/H<B7+.4?/<.7.<'B@?"E*!&+=5B(/8(C&8;3&(F&>1%@;8H!3>(-609DE=:AGC@@2HHF+:7>46!A2BED:6:*B@844>FB
@r455
TNTTTATGATAAACAATNCCATNCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTNTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATNGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCAT
+
("2!/C)43+<5)!9387271F6G310?AD+C%2=*B1;:/!2A0<.@(8+A72-A8$%%-97#?A:-2.$&!;,.9<9E#/E=)&.>?#4?3&H<&23!G&-/2:1-7A=8/G&=12$3?H$:HC0DC3430EG7>-?$>?#3"#?+BDE16#2*:!'"!;@@!C$$7%4-1-)48%687+G742&69&(E?:6FH2-:7:HB$?>88)B%/:F3FFF8G-9:%(H!6*(;!7GE<3$3#9/3$.?H39G@";!G;
@r456
TTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCNAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTNATTATTTATCTCCTCAGCCAGCCGCTNTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGNGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCG
+
/<1)7>/C-%A9.:,B8(H09FA5">,5$+?0E+$17%=@?@-H.>(;'3).2$&H56GD:DD=<.E/+==:+*09<>1@$';(2H-56?7@7*938*$!FB!$0!%/E9G3'-9;$,*>=**;.,9<A(8.''31!A'C*8.*'E2@E?>;@EA0-HC<#"99#-%/=0"0E2F+5+$=C:5*HA-5;B?;C.<8@CF).,#8G"1A*3<7A?E+E519@=C&..364$'$G/)2/#5,=9D9*1=!F!H%@(*D#/!1.>08-$?0>809:H%;>H(+3/:2$#2;*-$A'@7>48;*1$$#@.F=A+4F6;,0-2H0'/=H&,2H$<84D.10"?$3;2A%.;A"3E5'B:;?H$DC?5%6F3*.HC5;G
@r457
GATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAAT
+
A5)7'HEHD4<0.:;)985@13!D;6'GB%'+8.;10'!*-C.7
@r458
TTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGC
+
A!9@F2CB8'812;46'>$75CB@6/170/&",;;G#22<
@r459
AAAGAGAGTCAGAAGCCGTGGCCAGTGGTGAGTCGCTCATCATCGGGCTTTT
+
0'B5;!.=3;57/,)!&,A,C'1B5!5)0D?6'.DB165<!+H35'!=,/6/
@r460
TATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCA
+
/-"20=>6<GC&!;44)06258?)$B9/++"<+F*E(94H0+6$=$,#FHC:!6G94:9"H"*.E$B?+!0>BFH&DD66):H+@7)$'<H#!F/:A@G.7*FE5=2,?D+?$B*$"B&%68&3*@4H)B>(/>F:.F#<+:"3A743G:'59-8H0:=C<)?
@r461
TATTNTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGG
+
H<*.B.8G@E2"0HGD-G>*'!88%E1H*?8(6C:9HD66D38C(E>12.+,.E=A9,4E.9)*/&'&)*
@r462
GACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGAGAAACGATGG
+
/-?(4=8#'5/#H0'D)=52.#'3E(%);+A1385*:%>FG0(,&#
@r463
NATTACAACATCAGGGTANCTCATAGAAGTGGTGCTATTAAGCATANTTTTTACACNAATCAGATCCAC
+
!(G/(>'#2)"(@:=@0,=4F.4!0B)5D>6,%37G@%HB&%1<7(4H%.+!F"H8+,&.7@E/*(4;?
@r464
TCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCNTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGA
+
,)F&H3(/,1;6A7/C!25*,8:AH:-;"/!E#)(&;0C)#2&C!+F&%8G0/>54=3BE&*=GB3#E/%+"3G*3#B-58/=E!G#6F*DA*+C>EGCD&96H&?$+@<A&(A-@.1(>@$.,26
@r465
TGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACG
+
(B*#7A#F8BF4G8C>)F+<*C#$G$(.:5H+E5$:<2D0G?',:@+5:G
@r466
NTAAGGAAATATAGTTCAACCGCAACGTTTCAGCTGCTACAGTCAGAATTTATTGAAGNAAATCTGAAATCTATTATAGATTTGAATGACTTCCNCAATTANTGGAAAAG
+
'@%+6,GC(%=@12#1""&H;B7+&DB<-6E0G$23)$-(,+')64;1!H28?!"0;#+988$5()2)9%;@)8:<?>4"#0+(245HB"='@'+9-$493B5D>$8?E2
@r467
CGGGTGCTCATGCCCACACAAGTGGATTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTAACGAAAACGG
+
6#:F6"91$E9>A81-425C2/D196A$.D86=.*D2B)D92)3'!9GBDB.$A-19552<F9$&,.$)1%6*0%>;5AB"+=#CF.%FD,9F<9+G<$*(=4HG,8#C(<(0#8B0>B#-1=<:@'D2%&%3%#GH7
@r468
NGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTG
+
(*=FG)=59%&'(>'"#3)@H'C2%2/E8.20-<BH$B@;"3!6#741B5!6.2?!/
@r469
ANNNNGAGNGANNNATNCANTCGGNNNNANTNTNANNCNNNNAATNGANTANNNGGTTNGCANTNNNCNTNTNCTANNCACNNTCTTNCNNANCNGGTNANCCANNNTGANNCGGNACNNTATGTGNGCANTCANNNAATNNGNNNGNTNGTGAAGCTAACTANTGNTATCNTANNCANGGANANNNNNTGTNC
+
$!"!#"!#$$#!#!"#"$"$##"!!$!$"$!"$!""""#"!!$"!#"#"#$#!$#$$!!#!""!$$#"!"""$$"##$$"$!"$"##!""!$#!!"""##$"$#"!$$!$"#$"#!##!$###!!$$"!"""##"!""#"#!$"#"!!!$$#!$##!""$"!$!$!"$#""#"""$!""#$$!#$!!#$#"$!#
@r470
GCNGNTGTAAGCNGCTTNGGCGGTGCAATGCCACAAAGAAG
+
(&)')&)))#)*!'))"!%*"$*%%(++(*%$#''$*$#'$
@r471
NTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCATCAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGCTTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAGAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTAT
+
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
@r472
CACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCC
+
>-)<1B1<;@;7*?5/;!!6152+D$0:<5%0AG-67G(!:""9">?5-##4B@F*G8(6H4-0@@(0<-+@:!'.:#+**C<"
@r473
NCANNTCCTGCCACCCGCTTTCACGAAGGTCAGGTGTANAAGGCCGCAGCGTAACTATTA
+
""""$+"!#&$"#+#*$&#+$*('##)!'((('#'))+!#*'#""%($&)"%!(%&*%"%
@r474
TCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAANTGACAGGAGAATCCAGATGGATGCANAAACACGCCGCCGGGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCNCCCTATTCTCTTGCTGAATCGCAAACCGAAATCACGAGTAGAANGCGCACTAAATCCNATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAG
+
<<B+!69?66//,*A:E19=BE219D"5@H?%72!/FC=5(3C3?!A=34:6!A"4(E>5+:HH<0@";"1@'?#+B;8.:D9;A4!!?BE5?7$<<0,*G9)3;'&B"CB6)%B<&(AEDD858/%EH+/)H$%9*H5H,;EHE#F?DF%3=@3!:7&<;>*E(+10>0-$2F=&H?G(.@#4>94#3<))6+-,/<@E=(1/*D&+1F)>!,-A+*($(8.?B-H(1#.+1F)3#:5?==E"3-&":3**+/6"'>7%0BG3+-G1''469$?G9'+=577(&2>)E3(;'8
@r475
CAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATNTCCATCATTCCAGTCGACCTCACACACAACACCATCTGCATTTAAGTCGCTTGAACTTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTA
+
4%8;862&?1>(G6.B>1@;6?=4!71B6AA.!*$46C03+*G()H)3'@(%*(4H.,"9&2@&F<-G<7>".18#9.?5+/("$5D?B3$6"/73,$*84;32&06F>:HA6!30E%F&5?.G10>C9"B?04E(%+!(F($>>-=8!72G":@',"H'/<GBFF@5<$A=-06&0-%<GD7&8B1!2*>FF9E'#=0CG>B(-2G4@?9;GFD5"?'%4/;64>-F!'G2CE2(HF#E,:D9(;'AB$,D@+@%%6:C>F2554,2?,)1*.)*651C,&*#!6*%,+!
@r476
TGGCAATTTNACCTGCGATCCGCGACAGCACGAAAGTACANAATGCGGTNTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAG
+
00@*?@7(:-+++3./1<8C%3/B>8":'30&:=3H5"#A)-5/7<+EB=?=G4:?:37-5";44%0BB6D?C*D'A&)5F!79+
@r477
AAANAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAG
+
$**!)*%)+#)!+&+($+(**'*'#!$%"$%"##)!$$'"!!%#%))$!"*#'"%&+%'$
@r478
ACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTT
+
45;2F'".D3@38@8*,58'5;1$08*GF*1%2-6-D6C*09:E
@r479
NCATCCGATCTGCGTTACCNAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCA
+
!3:FBF;3.2C=>>?>$2E>/!@/)#C&:'!86$F4.-G(0?A7$.61%&-;.4<?*(;?B3$2#..#DCA02C01>"<:=?!3F+0E@G
@r480
CAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACNTGATGAAACAAGCAT
+
)DA8E%6G+4C<8!2!A!%:1-*1H2E.3E:>A?93#'BA+#2H!"2(">$C!"*0/B7*5E7C@50%/G%"7CGF(3.7160)<'"5*E>@F&
@r481
GAGAGGAATCGATTTTCCNTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGT
+
&>6)?361::C9"1D.*>H+F&0%6(9''"2?C='5H%!7.F@36'1CFH!9"!;:"E7>-=*(EF"D!238<@()E2(@=E*&;*H8"?5,&FD9*?!:D&'4A=F,9#
@r482
AATCATAGGTAAAGCGNCTCGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAG
+
<B=D&D&-'1&:@#:A#(",.&8FC&0E>82+/#",(CA-H*,4H;"G5;E22/C+3"!>2*."/6@:='B,<*91.F
@r483
TTCGTATCACACACACCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTG
+
./40@4$.?0G$(;?#90(*>8?134898,6:GE*@!;:D7,)!#<<=(4H?C!F32<?H%1><0E27<!F*+D!H%+0"/1%-=*@8<&18!B#$&A%F.
@r484
NGNTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTGCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACG
+
!2.3H3859@,F.*DE4,GC<H!A790%'CA.52)56#F#B3<5#<-82=.--(:'"G3-=<0#G@>?0?32-,),2&6&&"6%B80/"#(89A
@r485
TCNAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGTTCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGACATT
+
%*">'!A-5CDC+2?#B?:1'4B:5C0)/D>2/@0@9E=C21=C6)"H'!5CB/>#-'%7,D52*$%$+E$80H'AF!."'@G4E>H%>:'.;:E=$!19')<C--6*:;$D=!:0$4,"@>1@2<!G%??))DHHG
@r486
NAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCG
+
'4%(-8705B5';-:4E2F,C.C1<%1F.4B)A7*B*$H$*031?/47C?A'.+1.$DCD.?2B.<6FH"'(",<A)&2;<9!1:G;&2-71%*?$#+(=1<4&=:,'%<A(
@r487
CCAANTTGNGCNAGAGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACNTTTCATCCCGCTCAATCATGACATAATGCAGGCCTTCACGCT
+
#&)*#$&*$)*!%$%*#+%"%!&&*$+%"#!*')&)''+(++&")!$!#$"'&&'!((*%%&)'$#$&+"#"!!)*#!&&!&+!&###$$'%*)('*#**##&!%#"#%*&&*("
@r488
CTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCG
+
AF?$:.=B)%*(>(@+,#C?+#C47<)>/)E80E7534"G6@')8-7DF:$";D8"/3DD/"A6-*2A#7935@>+(C1#%E;F">*-#+1#?
@r489
NTGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCNGGATGCGGAGTCTTATCCGTGG
+
#2!=+8:7;"1.()(,B3/<;G(:..0(8DG+'?4*9:98BG<&6@2&1@E,B7;'5%1(
@r490
GCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGAT
+
1CB-*(/16+B*<>'?$%;>3"&*9!.G$('!G373G6*)6:'-#18'%A!-<:#@1$5("2&9<5"C<2?
@r491
CAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGC
+
7#)6.=)66?+!%--E4?A)$$,?->C9#)0;2?!'3F:>)F.-$-7-;?,7#+;"B=GH%:;D;H"/A&$H6AF.5!*2DF7)"E"F<)7/++0*--5C6F$.=8?HD/*DA-F>*.#E=:+/'$:E05
@r492
AGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTG
+
&)D>2.<>&A6"5D/=%C/#?=D.G!G2*$F%(@F2<=0F,<.,;?0:#5GB$,''F<=:7@,;;1G.:.)+)3@-9!D,AC!?9?/C#:,'?4G>=9;#F:=1GH.2B@)EDG/1A-/D$A=2="2>E&5E3#.>
@r493
AGGTGCGGTGATACGTGGTGTTTTTGATGACCCNGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTGGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGTTGAAAGGGGGATGTCTGGCCATAAAAGGTCTTGAG
+
0%/H>8&.-$B!=$=@-#;G40$(//02=56'6'D339!5C5<&3<@D+/-=42D:<6$H3#G2492/#;+'9:3<,F('17;1,C/-3G.9F6&4H.8/19--&#3=,30)C%'8+E*-)=8!4H>&/?H/@*E;);7+3=%3AB61F>.5D889+G7H/;;12C2<!$:D%G>G="*&?&A=2;+)G9>-6(3'0"'*FH+0A'*%'B**!H@*)?<4!B5,=+75F%5BC,<**%(C++#CE138H'B?!,6=1C!12HF0("D!%:*AC4-H(D4<#(
@r494
TGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGNTCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCANGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGTACACCCACAGT
+
.=#H(-B%)3C!G%B:;5HG2F$3$/:E>0)60.>?4C,A&=A204A+"G;*+@9H>/G%!.?%?!5758@?HA"'G&3%0/=5<0B-+B:9',0GF:?4;3/E2<6G3*367HCA&0("E<9'*%FG;1%;*66!+%,A7'6E8!.).?:GF;;,CHH9&628<G(6@3*?0788!1*:=A"?;.<%2+('08<A<H&!&C+!A0B0B@B1@04F3CBH#H!:"@!.:6BD88/!9@D(E->;.G"F#%7!8&7>)F<%G#=E8*#7''C1A=="6'+>"@!&5<!7G*4,>::$!D,%#F9D6(95?H,-/F>0%,@/B??6.9%CH#D!/8EB42C966;A(1"8';;C@HF+*12+$<
@r495
GGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTAT
+
18";D)"?$=,)),-FF)84EE$-":95%?<@##$>9,F-0<72"+?/B:F@0(-@-5@C%D<@?
@r496
ATTTCTGCCATCACCCCGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACG
+
>?D5BA7@3#4A"GB2:45H#F1/B#3,%+8G26"@=D17/".E;<07%@&)+D+'H46&2H?2+*;12@+781"9'7=)/%>@5$@;<4%>-F%:&(%>7
@r497
ACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGANTAAGGAGCGTGGCGCTTTACCTATGATTGA
+
7:1:"B=:6C$@:3%8E&:)?<:"F#+!*#A+3$B803%+@HD54$AH-C%!?,E%BA"7%+8H)E%0"*?+3)-.%63.5B$7G%?4:DA?$0#0?7,C3956."D87;!@.1F-<#E/9(+%8H+.+'66<907#A38<861/9<H,$#B-8+@!A*!$F'BC?&EA'".7/299=(-"*4;=%G"+7<4:$.>,B+?-$<A>*&%&D$160&+>/73#&":8.
@r498
ATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTC
+
1!.'B,8C&+>(=)+%C2A<6:*$#E>550++3%-*C+;"52'G+6
@r499
TATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACA
+
GAE@--&)3%-9C*0&DEE4D:/"8#C%<G<6H>!/*<#7>5-(6,:6=&0(*)?B7%?4/,$F.6$G=#<D4@G?//3,;?%16#=-/3%="&<2;C!'<>;%!7:#,@61E2,*5A,:6EBE)>0,G'6B6%35F#,FD14>$7<*)>(/1H5H=1D0743&/;'0-D&G*C:B;.A#@!>*#)-0B;4+30)D44?<=0@G(,+*%@?;H$D(AH)3EF,3$?C
@r500
NGGANAGATGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCCCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATANCGGCTACTCCGTGTTTGAGCAGTCACTGCT
+
')%'"&!$$*+"'''(%%$&)!&)(!"!*&*"!(!"%!$+'%!($(""%''!%$&"*)'#(""&!(%$##$#)$"$'"%&$*)'"&!$("+"!#%%!!($!"')()'!&"'*+%&+&!*&)*(!$"(*&'&&++*"'*'*!(&&&(!*%*""'!*!*%*""!+)"("'""#"$"&
@r501
GNGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCATCTGTAAGAAAGGTGCGCTTTGGTGATGGNTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGCGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATG
+
)%F8:<#7182++17*&!#11;/A'$0GA*<+1%D5122C5*DE-BH.B7D03'/4>D947?FG%+:2,<%<'>+76H(9B#A.;+8'(4-:G0;*HE8G*(+AE!?(9,4(0,-3#G<5*/GDD%,9C004H,7GF'H&9;H""7.:E14B+A2<.0B+-5FA$/4%#*453$5'"$,"%;?5,1$/"F&<)/><9898C@6'!*"1%88.)'+22*-B(;1(?7<E@2B8313>02E%H=#2@F#'!0"B11+372#:+;48-#3;C@.1EB9:>@C)(:A$@@F"FA*
@r502
ATCGCTGGCATCACCTCNTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTA
+
%H"9$/#9-%&-A.*?);:GHB@*;72D')?3!-@C51?FH0FB=38B1*='!(<.-+$;;D5!2G+)=135*G64-!(EE+G-<"E450@9BFE&G2$!HC#8;9D)7=,C-+34.>8E"?H2'00:6+&4
@r503
GCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTGAACCGGCATACAGCAACAA
+
.62810+>(166#7!1+@%$7C@%!B)>:FCH7)/6E!4*>9$-HHC2.8/>>*?#.C#0$=3A4)8>1A1,E&.82A20%C8*#1E>;'?:3$G9D5'
@r504
TCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTNTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGCNCAACATCCTG
+
-F=+(!@A/HH0;.7E=H#(:#,3D4.2"@#884'0.GD65&$=>+##C<:"@,-1F;;%A.E(G;&-BD>7&2H&),H(@%)!/?9FC'#3&)6B?)4C0?!/GB*8&>?;*8;>D@=*/HC;',)!=&.B%AF2G()83'>=#,/2>9/.H1G2,"60!D51)3F.%;9.()F#*F40
@r505
NATATGCTTAATAGCACCATTTCTATGAGTTNCCCTGATGTTGTAATTGCATTTATAGAACATAAGGTGTCT
+
"=55<(/;/&+9G9%78=356/'D--?A!6B+E!<$H6.2"'H6A6G>8B4?=6HC5/:3,@C@H<F+/)B:
@r506
TGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTCCGGTGGGCTATTTTCAAGTGA
+
34('2@4:EH?@)4';;3%B?D?>?./"F,"C=42%7*8'G2,0@7#7)@?FG5*>(G&49=DF+E;618,
@r507
NCGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCACCGGGATTTACCCCCTA
+
$#))&+++(%"'"*+*"$"++))'&#(#%+%(&')"*'!((%!)(%!#%$"%)#(!
@r508
NTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAAT
+
!@*#9H;&>/:-(E:$#A8;@736"&G$$;C84D<(AF3@":1EB>G(.-DD$E5<F0GA7H)6E606(?=,*,#A4A9BF(1!@E
@r509
ATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTNACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGC
+
E:3+A&(A07;$A/B+=3<096)A4#:/(7G1).5#D,B"CF10A3C7)4>)E$>?C11,-(.0C,*7B8)>*>/4"28'(.F+D+&B02<.8,8A(:!B"3>*2A.''@;E1G0E)*A:AAG>>D%@,-9DB17#$8@+,;.9BH:>-@+F2;!G#>2-#
@r510
GCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGC
+
-4"6'6+.)0-4(5@$/?;6=B72C:96.!$</&&/<.>2>15@5'&:5:?5:$F1$,-*'/"/>
@r511
CCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAAC
+
?9BH?B44!BF!<ECD4-#E"9FACF"!-,--C?<B0G80-"D.=F<(
@r512
TTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATC
+
F(;2641%8!:&)<;%*=5A3>?(&7=:%2&92&&"?+B=)%BF#/>*E)7+A$;"-%$",)#014B;;=&,/E*
@r513
ATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCANACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAGCTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCNGCCGGAGATA
+
,%<-6(3/(2,0H,/($69@+&.%@9<6H--%3')4?8$("1&%1?9@29(%#&B;6<H=D$2A;7FBC0>>,6BH?</##D&9H'23D*(<?!4!&+(+G#*/(:E$.!C1F-</'D#E?=3HFA;E.H8((A05B?G?5;E%9A*300&&:%?#>$73-319C#<5@=>)>#2$H)5:*"$,:B?98@%H(>)!A25"!BE17&D3?.F$4C1=626%(@3@9B4AG.6CC+!0*F?4!AB"*H0DE6C%6E,56%E4D74+5(DA)F?,(G>
@r514
GTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCTNATACCGAAATATTTGGGTAGT
+
,+D<D3'64:0%>6,GF=<+)*,C/(,4,5:290,D6E;F5!A:G>+>*F333=(9//680%
@r515
ACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATC
+
/<D"9-H.#6+)!#62$=C45=#3D"(71'2>2>).*D3)'..*-'0."A982)!&->04E6E4;#?$0@3*>&
@r516
CAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGNGCTG
+
9(@>,?947&4<&G0%4$+$#%4%+'(00"./6=H&4>-?13&.G.'BH$E5H;=%?C7G-H$+
@r517
ACCATACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAAGCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCNGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGNATGTCTTTTCAGCTAAACGGTATCA
+
2%::*#%&BA#?7>"D0:EE$!&%D;-=&"9+H559@<196B/!;DC**=;(@!B'@@(CHEF!"6;+)5!A&E&'/#(C#<(7F-0H<5A!3<5<?>:1F1)!;D;A>4'42#%&*5E'@5%64A@!-4?"B-F::/3/79F&5#-&#3%B-?9&'E',@>#2"%/83,#-!7>?@%:0-*#7<"<E,:..)./$8E7=*4%F7;)("9D':#67#@8?H=GB4+<;C;(G0HE2:EA!=,0E306H/C@:,"?713E7?G.BA(1>+$092E'/-B,415
@r518
TAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTA
+
;$'/=A,1437;1%;,B-%'4-6*!).!3%&#3H0A&;,>1/A!#B6E=F;768@)'?5D&<$
@r519
AATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGA
+
=="B!%43!FD4C7HD+9@6?,7?%;)9&9*=-G$'$AH:693'.H/3G*1F+=:#EGD9?=:(46,586A&F/)"(+14>=6G(*B&/4<7*B'.*("(-=-$@%1!46C;&2/.%2.4AC537BE;/FB*
@r520
GCGGGTGGCAGGAGGTCGCGCTATCAACCTCCTGCCGTTTTGCCCGTGCATATCGG
+
-0D)"C$?F?F$E#D4$$/;/D.>;E4>$+7152FHA98*<!<'C$?;'9=88AB?
@r521
GCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAG
+
>?C*F8,?!7(FBD?4!D@9!7G*H'B6!53'&8/0,>74=&?<'*?4?%$"<A!C7#!3*)6&/912(@
@r522
AATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATTTGTTTATTTTTCAATAAATACAATTGGTTATGTGTTTTG
+
=*(B(&4(.G&:7!B"<)#(DC61F/9AB<-/F=C:=0F%89:&2-+01D&@HH'87@%@*C*&($/=8*9*$"@14;(7*;E$1=D7C4C5<37:)F":50%>+="B'C+*&/%G'5<.&"HAFD$'/59A>95/B#F3&<C7)9,$B:52
@r523
GAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGTACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACNGCTCACCGTATTGCAGGTTGATAT
+
"GD(4(>,D+B>@)>6;,B<A>G&=8/7AD5A83-B,;27G5"553H-=")2-#5"F"H,ABH.C:+."320:&0.2)H,#4C;7+%BA>#+93D&0CH(2D7"#A=C+3-"-"C<1&F0>38=HE';8((52GD%169@%+H*'541(DB&6)3!#<)4*=<$,;4.=;'@!(&!F#G8)F06$:C)9517C44'!%?(+2-&7(/9B=@(+*8<!G=79G1!+7:-=,>F;>/@D8-.F/6HB>B2G>(7.0H;@4@$"-A@;:BGA6:@
@r524
TGCTGCGNATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCCCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTG
+
$*E)1?F>D&2H'$9&,$>;@!,1<&*>$4*-9(#D2;+,#HC/!@H5?'H@@=DA<(E/B8:)'/)D=+955F(#8@.+!.D':>)?A&>+=%C($'*!(;F@+)7A#+99E-?#98!6->22(;B:),('
@r525
NCGNGNNTAAGNAGGTNGACAGNNNNATCACAGGACNTNGANTCAGNNACNNNGANCNNNAGGNCGTNNNNATANNCNNTCNTTNCNTCANGANCNNCNTCNATGNANCCNGAATNGANG
+
!"#$!$#!#$$""!!$$$$"$$!#$!######""!#!$!$!#$!#$$""#!"""$#"!#"$$""##"!$##$"!$$""!"###$!!!#"#!"#"$#!$""$##!"!!$##!#$"!!"###
@r526
ANTGNCNCTATCNAACTGNGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTA
+
%!)'#%!&(%$)*!)!#++)$&#*&"#%$%%(!)+(*##&)!'$("!%)+$'!$#
@r527
NCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTANACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTC
+
*D&H;GF7(6E:9A<++;,<(750+BCFD-?#C>C6(9=B@E4A*,16=9!(1"2,E@B,0AFF=EGB5891>>#7,F&"0:<1@/1+$6&=
@r528
CGTTTACCCTGTCATCAGGTCANGCAGTGCCGCACGGGCAGCGGCAAG
+
D+90$A2C3021(;*E./4.4B9,,FHBAGAC!$+8*08#A*%7.E34
@r529
NAGNGTTGAGTNGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGC
+
))'"%)%*&*#'*)*#(*$*)+*%#)$!)'"&%&$%'%)'*(%(!'*(#%)!+!
@r530
CTGCGGGCTTCCNGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCG
+
6!##G1;)85:/3&)="7*B6<(>AB-#"*(DD-A41+G6*!>"GH*FG-6,=%'<<B@2*'/!C>!->1$'8:9E73A:DH3G1E)616."*A9CGC@/E23%4"9*C0G"#!*=
@r531
TCTTNNCAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGNAGGTACTCAGTNCGGCTTCTA
+
'('(!##'+*"&)!++)"&)#"#%+$(#'%!%)#+)!*##&#'(%"+'(+#'"#*&**'$*
@r532
NTGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTG
+
)2&33"33"9C0*AD?(+7HCD6;E44/F30B==C;?85-&099F97@,!
@r533
ATNTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACA
+
,/A",#"6#<$D:D509#H##&G>1A*$*A'B,DC*@$4EG+026*((&B4/!)+((!'"2/4B/=D>4"7&DC(FB<&A:52C&&0*3.'GE"A#?*(%2@=F(:4.!'@24#+:&7$8C102.6/?:,,3"3&B$+/(9+GH2C;E9,81;CC+.A!&@0E%
@r534
TTACCGCCGGAGCCACCCTTGCAGCATNGGGGNCAGCCATTGGGGCCGNTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGG
+
+&+#G()6C%-'D'GH?D$(F@-0$&.4/8/.G4>C@&<8B>.;98;<5>&5;1DA2D1CC/*8=25'@!)G++==<"7.0"7F"C3D+)
@r535
CAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAAT
+
HH(C2HFDD<;H3$)%6D%=@535?9<B181'-@A)<4E@/&881E$H$="*@&FA
@r536
TTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGG
+
)2#E>92.0%D,.C?C<28DB1);?AD0&+9#'FG164415D0B70@633(77,06%<A'#<?B='=$#A-0C
@r537
AGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGC
+
4:#8+;<G62AG"9G5-3DD$D)!A;0'H@>E?9H>157F18/)3"C&;B1A(%G!5<713*=F393@=9(<!E@E5D'/>BE.86C0A7;AB25BB085;5G6%,:+*7,4+3%@2.<!4&-
@r538
CGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCNCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGAAGATGCGTTCGTTTCTGATGATTTTGCTGCCTCT
+
>!&,;!9*G>$2CE.=-)E%5%&5H+6G)H5;352$<**=.:*F,>3+0;CD29=57791>7"F1@'B;;01<GH2<8&H>+4A:92"-C)8H8!F;=/?/""F1!>!+?&7"@&,GD3;=9>.29>7?<0>B(G")+%*#7"E'8/@-+$G?CA;)
@r539
TATCCAAAAGNAAGCAGAAAGCTAAATATTGAAAACTACAATACGATGCCCCGTTAAGTT
+
B;F%(-"G!3A&%A&32D;$,0+%.;6C+>B%41&(D=.(-'?7?:>,1*'#7+9#--G2
@r540
AAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAA
+
<*<$@-!<C$??!/=4<G!0>47?&9=,?&/0+<!&/57>8(3F>*20<2.16E')0EDE8F'GE%C&:7F+4B+)1'?7754?D$>/
@r541
TTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTNGTTCAGTNCTT
+
=2#073G,A26@,,C@7C2D5CE4%>6C.0(:.,4-G3#@>8'$$>63:H62.E(,-:EA8@/5G%*/A1C$(G
@r542
CCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGANTTACNCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCC
+
:-0%4&2?HF;#6.3D&E8-AF2=<60H$3?%0&'$/,*78C;8?:+)AGG6@%+FC+@;FA8,E<99&6-9)C56B<7BE)*?:(D+A!=80D23*#>0!,=&1%"=F1
@r543
ACTATGAATCAACTACTTAGATGGTATTAGTGACCGGTAACAGA
+
/+,E494H6$C4->C&2,8A@H?$F''AA(.FA8''EA)C7G-.
@r544
TTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACCTTCGTCTACTCCGNTACAANGNGAGGCTGG
+
@@!.$)"AD64*F5,$>'6E';='7!<-4)#,4C31<4"B)&?&6/,81!A:G2DG@!702?-"?<4A%*CE=<$"68*161$F6@E+2>A$81
@r545
CTAANCANTGGTATCCAGAATTTNTCACTTCAAGTAAAAACACCTCACGAGTTAACACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATAGTTATTGCTTCTCTTGACCGTA
+
&""*$!')+*(#(%+'*$%"!!)*$*())&#!%($'"%('"(!*+*$)!#)"!##%#$("&'#$#&"%'"%!!(+&+&+)#%*+&(%&(*$+"(*)"(*'&$$"!!%+'()')'%%+(!+#&(
@r546
TATGAGCTGAAAAAGAAACNCCAGCAATGTAGTGGCGGAAAAGGACATAGCAAATGCTTACGATAACGTAAGGAATTTTTACTATGTAAACACCAGGCATGTTTCTGTTCCGCATAATTACTCCTGATAATTAATC
+
5=&'(19)$DEB9*23&1*59>A#)!-A:D:@/G97#AEG7/0%"D8=!761&&:%30AD&%'.#;B<4D/'-74B9/-+$'7H$8)71>&&544>(-0.!:,47H@)E/65%G3.'-;/*6B9;(4#?)#H*E?2
@r547
CCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAG
+
F78G!A*&9;"&7"=E&@BG6"BG)0/F7C)$,65"17=:<6'EH'2*FB'>$:.B/=B/81;0)8C+;43$>0
@r548
TGAATGGTGTCACGCCGCCAGCGGTGCAGCCCCTGACCGCAGAAGTCACTGC
+
0-G13$=42(1G'DGE10A'-(3EAH!0<-=/A2'1/=:;(:1#(.7%221C
@r549
CAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACATCAGCAAGCAGG
+
.A3%*)3B$1&%B6<@.#/%D,;0!1!FEB4"$"(06=CH#BC&B>/A#F?;0F9154B;GFA&9A1DG.AA/8;FCG#9:EH:"(1320094"=72E
@r550
CTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTGGTGTGC
+
.#@B9C)*?A+3C;$A/7C!-G5$9%)E>37@2A-8$2$<9:/H>$6C@2%5D#)84783-!#77";E/G.>99/9E845:')",/+3BHD'5-DGA(7"21>/@C$3##C.?E4.E3
@r551
TNGACGAAGTTCACCGCATCCAGAANACGGGCGTAAACCTTACGCC
+
$'>&4HHC;=&<G>'=C='-1#3-D(-HGG+<E&=D=)FH"H3?0G
@r552
GAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAAT
+
.<D3(+52&(GF5<80;.?)FCG/#!%9!0''4$&*!"(=*F/%D8286E!HC"$"?1;");@8$/41&B1'$>0:8@'41#&=?B.+;6H'51''E
@r553
CGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATANCAACCGCACGGCCTGTACCATGTCAATCTCTGCATCTTGCCCCCGGCGTCTCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTNCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTCTTTCCCCGATACCTTGTGTGCAAATTGCATCAGA
+
(&2-+A>'*DG("-&>&86G9BB!'+(%A$@14C"6(/&(44,%*C".3?404!?#<.7D:%>:+A.2(D91A94"?@+D4D.5HB&%G8$D='G,?%=#-3G$,?10"4F*$H0GG/?.;0.GD!4C!&5=<"0@#76:;B+;F..H$*?($)*?.A;&1A!&8GE",(EC?,?/;%":,0E75"4<+3)4D$)&9EH,#6&5.C>$;+4>8?50-B,$BC)14A#:G72$7?GF"8.)!)2.)
@r554
CTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCA
+
CC.-)F7ADAAB!+=6-1(8@@"A?*/6!<>%CF6?017'6E3$;6'6*A;:5$,3>6-G$.?9*=)23%$++3!3
@r555
GATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCTCTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTACGTGCCCTTCACCAAATGC
+
FA*?%,C;.G&6#3A82",8$7B&4)6@88;E#?#+>%#@)C:F5?AF3:*G)9E4&&A'(A;?6C>$-<(#?8/'?>+#*+4'(;'/E<:71A=C::B-$H@H%.99%:6E+!=4DA-F/2F+
@r556
GTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCGCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGT
+
*HEG86C#E.A#*2G.#!0,;/G?+-0+#.G-1,1@E5,;9?4:G4@!4E1,?$BG&4CCB04?;?;76&4&C<1B;8(H2%D!8133;):!C>F43@E.D.+0+
@r557
CGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTT
+
&D0"EC=%/0H@84!--?9*>96F8:/8%%.4;>2D55=B
@r558
CCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCNGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGT
+
F&9.;+773./#40(:78)@,&B27<6!'$@D>!6731@AF(A7'%+%)E3C++C,$-C.H!9'C:A?B5>=:H*A"4!27-CF$'$D"A4+$4;9)ED:21@%6221=:FA?D:+$2G:!3!(H%+1"(&<1E':6*3&5;-&';8H+3#**'G3/)--()5!2&$E)08+:,,1,)5,8E<&H')'71=+.B&+'9@+5*+E77F;#9B(*;"AF>H3201"D$@#6EHA4F10
@r559
CTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTC
+
/#3$A+81DH.FH!2.C&8%A!C,>;$75C#"@4EBBC7$*;&4#7B-.4F*
@r560
ATNNGNNGAATGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGNTCGGCTTCATCCTTGTCATAGATA
+
"*%%%**"%!)*"%+#$$#'+&$))+("+"+('('!'#')++#''"$%$!')!&"#$)$%(&)*"""+&'"""$*$+#""+&(&!$#)#+%"%"+&#"*%$&#%)%#*%&+()((+)!!'$%$("(
@r561
ATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTT
+
*0+7"/8A1E3;-A5A,584);1%@96,'!8=3?<3)F//!E1<.0;A)(A()F)#93."!)6:E'D-0;=0.DH?&8C1#$E."%+!&/@*$G30
@r562
TACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACG
+
;>4=D8?=C=&:A>+6<F*4C#FH9'$%1(88E6F<0%3,G/!1)1
@r563
TAAAAACGATGAATGCCGCGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGATGCTCTCCAGAGTGTG
+
0<:?&2C<=@-1*/%"35+B-)0FB))*4C?D)1F##/G8FHDH>-4FC&!;"'+1CD-&G3):(5458.=
@r564
NGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTNAACAAA
+
#+*+)+#"#$*"*$)*!&*$'(&)&%)&')!&##+))#++$")'"&+%"
@r565
NGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAA
+
%+'%+*&+*+"##)+"("%'"'#*(%+&+''%%##&)#%+!%#()+"!(&#!()+#%(&&#!((()$%"#"))'$"**!%)&))''!'%&+("'+&'$&)(((*&#)#((#"!%#(#(%!$)"+(
@r566
CCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTNAAAGCTGTTCTTAAGCGCG
+
;7*$D5C-,H0!?)2%>"(G2<"&+=<;!%0)<17$F@8"A7'/7F9!&$H&6.D=!1?(BB&<#@&#')=E$2
@r567
TCGACGCTTATAAAAAATGGATATTAATACTGATACTGAGATCAAGCAAAAGCATNCACTNACCCCCTTTCCTGTTTTCCTAATCAGC
+
5*?"F(E6$'1H!>8,B+=EA5-<$+54G<(-62*::C68C02188@!64H11"C#=F%$)(#938*4%$%@&@E1D6/(1,A4"2+(
@r568
TCACCANATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAA
+
1)$2)8:-!*DB'3C#G2E*:1"+*5.;4.$#C3B3'8/9CF:6C$2>%3
@r569
TTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATNTTTGCTGTATTTGTCATAATGACTCCTGTTNATAGATCCAGTAATGA
+
,G:=,FC;712!+/8+,/>H59;>;*C):5G+C,?%B-B&8=2:;329H"2#C/E3-,0E>%??+772&1)%<.C!!+G"A3*97#2*$!=>A5#+%/;5GD:DD64%#:-.)@F>:E7><;6/.F05*<B
@r570
CCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCNCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCA
+
5CH?&H?$&)09*<ED!=#,$*!!/$&:D'(-!E,DH&<4/*0/%&B>H>4.9'23/H<)6&6*5*'#C07;7A?-=2%!EG!5%4
@r571
AGTCATTAAGCCAAANTTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTC
+
9@'5@2E&2!)495$?&#E6#/211D4@#/D'@CH);,E%07)E'6*%$-%)/5"=&80/D$%0H&&F$*<
@r572
GTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACA
+
<++@65A24!)7D(@?"C:"#7A6)H0:,2("@F/'@"&B.A,(3.@151>
@r573
NNANAAGGNGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTG
+
&$&$$#('+&!!$'*"'&!''##*+*!*(*&&&#"!#%("%#!)+$*$*
@r574
AGNCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAAN
+
'C;A9*,GB2!&EF&:#C/7'=6+$"$=9)ED+CH,+H;-HF8.!@530:C/);0>$?78.89"E>5/4.2(9(+5#2!#<<2(':'H>G#.+1:D-8;'=?FA<@F
@r575
CTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAANACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCNGTGAGTCACC
+
,C2,C+"=3FF8109E2"+#:"!,B?7<H4H3/1("#7*A5-/F-4#ED58+589E:'5&2996B*0D@5EF'H15'!,=0>"$)9$-&B:&,,$EH;&CFD&,E3/H
@r576
GAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAG
+
E)<4;92?&683&)("=6G(H3<43'&1GD#2(,#%21#,:A!$10/=A=+G$A.G
@r577
CCCAGGACAATCTGGAATANGCCACCTGACTTGGCCCCGGCGACTCTGGGANCAATATGAATTACAGCGCCATC
+
8&;-7/'4A&8&3;-'67@)2);E'448"(,0FE)+G0?-7-:?'89;6>.A=;2G5&0G)65&+)=$.D2/4A
@r578
TTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGG
+
F8*GB7*'(!/3>(;4.1CC!6?8."F0G;1G(1BG$5-5566(7<9EB&4$G.&C!1'%!$;AD@0
@r579
CATTTGNTACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTT
+
'$%""!$)*)*+*!&$)$(#**%#*+#)%!!&"!*+%)(*+'$)#*!(!*$+!&#)$'&#%$"#"!%%!&&$*
@r580
TGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCNGAAATGTCGATATCCCGTATCTGCTGG
+
6@.;-*$/7*'5B$2;=,824/#04&*H/%D,4B+.?$E5(5+0?A-G@)1%H&+D@2;1B&19()&
@r581
ATACCNCCCGTCAGGAAGAACTGAACAAGGCACNGAAAGACGGGAAAATCCTGCAGGCGGATT
+
,(&&96@<A/+/"BG%H0!G0!&)>/2-&)-64?0H+))>BG?8D1.3*77H8;$.3E>94/E
@r582
GGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGACAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGA
+
-A/%-9?B0D'2%6)A'><%51?C)/C&06EH>D;(F7HE<#)D!&.0-'+-$(3H<F/.0@4.H:?">G,7'8<7H1':<-%3#B;##576!1*5:9??*0%A,3
@r583
AATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAA
+
4F</45$19F5F>%*0'&23:B5=##%BE><3!;DD@#7"#;''58C,5F=,$14F)30<=7GG#8(&5.!"F/?
@r584
CGGCNTNCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGCACC
+
'')%#("+&#%&"(*$'"&'$%#%$$'$++%)&+'("))"+*"*')*&$$((#((#&+
@r585
CAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATT
+
*9;@+.E0H.#A2.;#/=<C0;%H?)$#C-*56E*$0#*<78%:)6D++8G:8:7&%/8+,6:)@+G7#,4&0&>@*B/BA7+A76=E+6$&-A:D&/=1$)$">37%07:%2$F
@r586
CAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTNGCAGAANCCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACAC
+
%G-'/AE6!!D9,<0"/?>'$9A%:/A%"1B;478F53HE/0F.DH0F%7.#BE,A51+</B!@65:=A:"1F=9.>'0@)*&"!=<&98<)+?!#6*5!%%%!,.3D41FA%8CF'+B>?3#3G!2"9=%G<?<;?#G6%G(2G;+'H/>9,+#"31*7)F*7+%FCD?/.800,.GE!.AE0C8EC1275-E<-A9G311.8)6F73..62/H2DG/.3::97>)9:;-72-@9@@64E*%<8'HD=;"@"5D"&F+;3.:26@0!9;@,&2*!+A=>16E6A+917A;
@r587
TGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCG
+
9&@93DH<+AB'8B?B")?FG>'#*G?)B;3(.5"<>@?*"8E">2DC8+3)0)/"0>2)=>FA$%4:0-+'74#81FED+9,@=CC/07#1>'03-?G:))50E>G@B08=<C0G')H45HE&F#FAE.6<;3F1@&B9&/5941C!+(1:;8,0"@.CF>417(H-B-D(-$;F+!6).8#'/6#=8-'B,EC$2D5B02F@8@322*&=C)@)2:C&)'@84D=:%)D-$C$0D>F@B1C
@r588
AANGTGNGATGACGACTTATTGCCGCTCTGTNCNCAGATATTTCGCCGCGACANTCGTGCATCGTCAGAACTGACACNGGCCGAAGCAGNAAA
+
('"!('$)'#+!+!*'+%+(*"(+#+!&)$)(!#)*#!&)**&($+#%&$$'"+#!$"%()$($')"+$*)%*((!&)!!#!&'*'$+)(()(
@r589
GTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTC
+
B.D("5@7E-:?<H;#<3$"F7;07CG))"F5H0!7H#22>%9"5&!5D?0E.$&H)+E"8+;?E
@r590
TTTAATGAGGTCACCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGNTGGACGGTATCGCGATAATGTATTCAGAAAATGATTATCGAGCCCNGAATCAGGACAT
+
0;!@,-G$+(E)FG0=@49('&@(B9:)(=42D/@72.B-"1!B8(7@!)E6#9;8-E0?>50CG1=$."6(D,9$1*:+3:D7;2@!7FC0F5<(#H-E9$.F#"55%#?),H?1;$?C#69$H%*2-=E,BH>D11,2*?D
@r591
NGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTTGCGC
+
"DF3&/'/A3><A,(.&3&FD&E<9H'1%>B::42!A=65,3@*:02?0=C9.C)+/)CD":>D:C/.&-:"4)*"EDH1C.+6,F-@:<
@r592
ACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTC
+
'+(#!+()&#)(%"""*%!$$'''('#'*)(+"'%'#++$%'*%"+*""&#$!)*'+!'%%+(!+!++!#%!&)&'
@r593
NCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCT
+
"($'"+%!'(&'&*&&'&#%'!'$$!%)'!"##$*#'"#'%$"&
@r594
AACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAG
+
*@)/6)>622,$.=52'4BD:FB32G&2FA$?)*1"B#24F*(',BG?<%"E,8)+;<";-*AA+:<@$H&@F3()629:G'>/F'&;GB?=
@r595
CACGCCAGTCGGGNCGCCCCATCTCACGCGCCAGTTTCAGG
+
E)B0>:;&8DB60F$72,7:2&+A7CG$7C(C1>?H>H(1>
@r596
CNACCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGC
+
%!#1$<$F8!1F>G?&&0D&.#?'E7(&D'=>F75%:6GD7B@)C-HH?>3G1#+
@r597
GAAGGCCAGACGNGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGA
+
>:F*31$&4$91)=&6(7:6&B($<FH6*<%8+23%4GH+1"C+3#$38=%*:23
@r598
GGCTTCGCCATGTACCGGGCGATGTTATTGAANTCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGCGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGAC
+
E;/=2"/11A/D&*%C"A);H)3D1E;E$'!@&'+.-@:*14?CF.%#86.2FA+)#F"F:G-$E4D+2$11!>%'B741='C8@0BC&%&-.>'CF,)E7D4AA*B,$
@r599
TCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATT
+
CD!E7:B>E",*B-"H=$9="B$<0*"G6F594$'!9<5)0A6$(-B3?)$/?:)(0EE+6<0G41>>?F"AG0,H@??:CF/(#.')%66/?&B3,=A*.H0.="%7+;8231@/&AFG?;.=0D-4=(;&6)9&!)8<='1<990A6F),?$D#:4?:4.;.72#4H,*;(01$;60#CE6E5E")(='>.C:C.%-2&'3538G-3?H*%07@:@.%>$?-&:&1%3,C;*%F&;7?&/8"$5=%$F%?4(0@BE#8/>$A(8B7HG%:9!7<9E>!D.#:A).-,8&ED?F.G/+3=)
@r600
GATACNNACATCTCTGTTCATTATCATCGCNTTTAAAACGGTTCGA
+
'#*('""'"++!"("'#&)!%)$++!#+&&+&)*%+(!+#!$&!$#
@r601
AAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCT
+
&-A?D5;>1*0:(4-:F.#?E3)@>)G/5)G(#>-'G:.9,?$G?!*&+E3B)<.6&0406>':(72;%E"?AA%32.7E</A%?":-=B57'7#7H,@4/+8=!">?%8%5G/:F5-@1D,G2?E./%"G(&*@<#A%&/0(7:B"#EB%>'7FCGE;.7
@r602
TGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGG
+
0D)D<CA;E!6-4G'89'+/G?E!3(+?,@.'F4B.A';#>;/@<*!'E+-7G:<2+"?0E$@:B#%F7<F:F)*9*3F"A&>88@9':2-G>2.7D0&4/'%(+'?0970HA1H90@D/"(G!B+7=F&-E.B<<$B67/$&$A04G1>-=D!/0/9@#-"8$E0;!E&FCE'/E#5>E.G
@r603
CGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGTTGCCGGACTGGCTGATGAAC
+
2@F1,GA7"*A?B,*C%:*5?-!<C;1.550=56,58@9@#6=":68E#!4@3-?.
@r604
AACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTA
+
08(F,0/*)F8E55#<!*0&=A>!FA39C6!H(71A:HB#)-<418$=<=>68B)%7A&$*?!$EC@84:8&49E9D3/A'%;B'3.D&@09B-&/;A*G"B::5.=#GA?4G-+">$>
@r605
NTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCG
+
(8*=F/12-,B<4*&8#DC(-F+87E-01-1*:6*5<@1:=-%+C@C92'7'",95G>3"=*(%(!@)&!"&<C3;2AB4<>2>73;%H0)B>17&EG<3?D:E++C:0#!&/3E-G5H/CB=:F6$#0?>F$;A':8?E(E0HC2%=0,('>(!2,H==+/H4005)0AC;
@r606
AGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATAT
+
H<71G'45&:AC+(AF9/;.0*)0.1DB5"+;(G#E06?/=0!6C@2$2-DF%"D2+4'<600++A)&)3
@r607
CTCTGTGTTTGTCTTCCTGCCTCCANTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTAC
+
B677,'=G$0E?4#!G<4E%EG+&B5D?7>;'C--2$=+4.EB*E.0G%"C/6HE%8E9;1C:+3:.$/?B4(%@H<6,1,EGD2<A4'0G,./C#/?>62.E3(CH&G7FCD3:'.%!>D$9$C6F>(<4G0++;%HC*8G4:..5;
@r608
CCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGG
+
H-(#=+)$9.E2<$E/8<@8-545;)*:7A<!1AA.!9!7*8C<@G:3-A8<E!"GE((9<69A5#5$#
@r609
TCCTTTGATGCGAANGCCAGCGTCAGACATCATATGCAGATAC
+
&@EH3"!*CB?2548'<"(&2D@+<1$,0%FG5-**?11@!7;
@r610
GTACCGNAGNNNGNCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCANCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCATTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACAGGCAATGGCCTGCGTATCTTCAACAAGCTCTNTCGCCGTCTCCCAGNC
+
)(#'(*")$)#%'#*%%('(+((*%%+"(!$*$*&+%+$#&&)("#)#***'(##%"'+#&"+$+%#(!')($"&(&#%%#$"!)&!(%"+"%)"+(("(%*#+++(%%')"+#""'%"')&+"&#&*+'*$*"$%'&')#)%%$!!''%()("&&(+#'%&!%$*%#&+%%$")%"**'("%$**%'&+('#!+&#%*)(*%$$%%$%"$'*"'**'#"*%+"*&($'')'#!"#'!(*(#%&&++"'())+)'"!))#**#'"%)&)**$!+("(#'&+*%"&+(*'!("""'$$*$!%&##)%%(""((!*)+!"!%+!+%)$)!!
@r611
TCCATTGAGTATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTTCTTTAATTTTGCTCATGTAANTTATGAGTG
+
-BB-*-G9<DGB/-E#/#=>--H81!!H.(90064%.G+'>,#C8%;-69A2)%<$+772:6D?+@!"#,)#H5&F9"!55"'1#<.4:C:@$0+0D5-@9H0=
@r612
ACNTCTNGNNATTCGGGNTTGTGCTGGTCTGGTCAGTAGCAACCGCAAGAATGCCNACGGCAGCACCGTCCGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAG
+
'#%*!()($%$"&#&'#)&$$+*#+$#+'$#'+!(*"(*##(($!'!#'))$'$)*!*+"&((#&"))&%$$*!*'#"+"*(+!%&#%%!)!"*$"!$**(*#!%)%)'*"+#)%&&("($+&+'*#%!(!&")(&*%""#*"$)##'!)#()'"&')(*$((+#*!%&')$'$)($*%%'$**%#%$'$)#&'*'&))*"'%')*%"$%()"$(%"#$
@r613
TNANCTACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCNGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACT
+
*$!%('()+(!+()(++!")&$*+#*!(!*")!(&)'%$(&()&''&+#*$(&+#!*"%"&"'!%!"&#"("*!(*!$*&"&!"!(&''%!+&$(!&(&(+"!()()(")'(!%'#$!'%")$%%&+'%%)"%"$""$*%($!!&(**+&&$(++'!!#(*
@r614
TATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTNGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCT
+
-D>?0;F+$!9B$>-06G8A:6?GE0.'"-DG<(1F($CC=&6)+&A=5",A2$G"*@?8*C7"DG/,<4>;,C%1#294@,
@r615
NGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTGNTTGATAATATTC
+
$5(=@*!(7"C,DE/.*81="#"#)#5*=!-@7C+/$07&%/,.$'"*@&:%;.?9?>47)#GD.
@r616
ACTCATAAATTACATGAGCAAAATTAAAGCAATAATGAGGGGTCTGCCTGATGNTCCACTTGAAGACATCACCACAAAAGAAATTGCNGCAATGCTCAATGGATACA
+
B#5%2?:7/3"6@"12!+257.'6GE;C0FC08A"&@12F(+?'%/3FD%E2C="::+F%E7%(?%)>@@:6&7;8#>A.0D,/D%4E3+40'2!C%8)@C1-D/E(
@r617
GGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATNAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCGGTGACGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTNCATCGGCGTCATGATGGCTAACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAANTCACGCTGATTTACAGCGGCAGCAATAAGGTGGATGGCAACCCCTACAGCCATCTTCC
+
+#+#9!EH.3+GBF?E+C5;1?D=;6"((@G<B"G@6A6G<09<#&5.@9:7!.:G('B672$$:*F+C;"(0'&7/=),5$4%)H?>FD1E)$73B.<=':D0"D+9:9"&2,!:72(9B9*@:%7,ABGD!B2.<B)<8H?D!8AB@<D4@0C<.CA+H@H=:&.54/;%,.<D0"084;<,$DA&$CAC0(H0@2H,G!A3%$38H/D<55.%5:"5AH,G:.*#:6'&H+0+?%1%/-D..C@+3!.>A26C879GH0*2-.E%A@
@r618
CAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGT
+
7H?G(:8%'B"H26D"%#9&@,D->1F(81F!')-"F!#)E>&=G<:;"F80','$C):C5),*H#>1(D*11
@r619
TCCGTCGGCGTGGACNGTACAAAGGAGGCACTGACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTC
+
7'F>$,"=25>58#<*>1EG""0(<*$;>=HH6.3%$?3A55?)+D>(C+"B?;(838'E;-%"/'&.(C.:GCA/GE)E@5>
@r620
TGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCNATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTNCCGAGATGTTCCGGTATTTGCAANTCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGG
+
-=$%"?=!,2A)"9G;9*7>&&>C*,7;2$@,AGG840"FA3ED)@65)%.8-9F4*#.3F7B;?G06#G7HFA&36!&/=0*<.&#4<>:3..D3/C&".G#;(>12!(-8(B>:H22,H93&21#6G984/C?5B$;53(6;G#E&'!=F1"(H(A?=1;?H$,HC&>C9"GG066,5?/0+"#':#9.)&#72,#+0$;CEG86'3@%83!B,=F)#E.H&616!=:(-HD+6%D)'?!*#<
@r621
ACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACAC
+
7>#5:!"HFD%E*C+ADH!64/2?E"F-%=F7,,/<.6<>>#0G8<<,
@r622
CACAGNNNCNGNCNTTGCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCANGTCCGGCTTA
+
'%)(&#%''&(#"*"*!+#"!"'+(*++##*#)$)%)+#&&!)!*#'%&$$%'*"))"")*#$!**#$!!!)$!#%&%'%'%#!""
@r623
CTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCNCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCG
+
%1G!=?,."6:D*>*'3DH(=GA"3376)40#C:%,:#,39!*7@;52>E).0:25,/F3D%B&;E!&EE3<CB!7::H&5+$!2D2(@
@r624
CATTTCGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAA
+
5(,+&>?95.E<23=D">8HA$D,#D%9<'@/;?.D6:9$H<=$
@r625
TTCCCGAGTAACNAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTG
+
H11.6)8/G:!72D;%GA"?3@0@GD1$?5$A=&B0&6C9(:$:!#.B314.(/?&2(0'.C2!-G67B0-BGDF(.!G?2$9'&$20%'"5;*
@r626
NATACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGNAATGGTGCTATTA
+
&)!&#%++)$+*(*!''+'(%%*!%($()++#!"+%&$)'"&$()")%&!&)"*(!))##&%)'*
@r627
ACTGATACNGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGNTCAGGCCGGAGCCACAGACC
+
H+H:>/+,G?<.''9D5%DB%3,6GA-03H0(*<>&+.&8?4;B?HG$>*=%5EH?3A-=CCE0$>"E.-B'>A1==28$2&D3'4;/?-%&98D%:A,/8.(3?=0
@r628
TNAATCGCTTATATCTGGCGCTGGCAATAGCTGATAANCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAAC
+
@F),+)(%3A=(,'F$,44**+':9+8C*2F0@E#(39>D?5&(1;!<H('B)@08$")F9#F)CG+#'6D)'32A6<38G.C/@E+)':"B1E=:,">6$-E,#<2-=*"58&920%,FE/BG7"#H->-<;F>#$)E/8CB6!EB*!8@6H$1$$-",.*-
@r629
ACTGGCATCGCCGNCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTT
+
CF#$26/"$<7*84G:47>=A>E5F?%4;99@G"=:8-9)@HF"B'=B6,2,E'%:(H&$BDC3.F<3!>9;H9:-C2$$A-;"5.
@r630
TGCGAAAGTTTGTTCATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCC
+
C7=@9B8+2H*0GG//A1%?F?=B26G92EG1AB.=234F%$(:."!8A?)<,2>"F20E"$&=H;@/%#6@4*18?/*5C"$,G3&+(#&*
@r631
NTNNCTTTGATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTNGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGG
+
")!')##+*!!")!"$$**%"'&$"%*&+%)$!!!((+&&!%$+(%*)(%')($&$$$#(+)$%#*!)&)!#')&$*!)''!*'##%)'!"#!'+!(&)##"'&!)*%!+)#$!#+&)&$+#%()!")%*($&&!
@r632
TCTNGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATA
+
?9H;:.47*$(8@&4=41#8F!.9%?DG;@@'@E!@6;23H,*A9,//AA'FD?>(16<&%,;G-,0$*.C:++0->+44<9:9-D6$3D<-7G4939$20&!/A&HCAFAG(.E?>.
@r633
CACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGNAAGGTTAGGAAC
+
),.G=F2CCA*$9F+@*!5(F5D,F/15>#7D"A*?B(0)+*)94!.D+*,#=0"A9A&B+
@r634
ACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCG
+
/#5?%(.*'7;,/('&B.H57<-DD@<)!<-48,9(0B!57*"1)F5#'EFC','&:51)>:5C"6E5GD0B%+
@r635
TTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGACCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCT
+
+4GA?>)8D;>G7/-01GB;::!BC"@6/,:16B@,4-ED(4,;EB)>)9A#F6;2+:;/9/*F$8)6'D#@6+4GA0=.B?-,0CH$8!C8$A6*@60437=C>2<8H&1D:F*D:)'!,#-5@=&&.EGGH/B+A(;6::
@r636
CAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGAC
+
A2A$*5)5"-(4A<+=2?<#D$C778E/8B2+=8)%-9.#8DD#/(>E5!C!&)<C
@r637
TGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCAGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCG
+
FFC&*!25;5,A:9);A9266G=;!6:-1@3!,E-3"7.'BEC;%?82A@=+1>$$)(%AC93@*:H2(4G/==(;$-067-,7&057(B<E193>8;F+D18:;FE1-#?-!'CCB!,+>0,:);
@r638
CNATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCNTCNGCCGGTAAAGNTGCCCCACNC
+
'*+&#'"'+"#)&')("'#"(+&#&+"*+)!"&$'***&**+#$(!#(+"#!%*("$!#$+&!"$%$%)$)%
@r639
ATATNTTNAACNGAAGCTTTAGAGCGATTTATCTTCTGAACNAGACTCTTGTCATTTGTTTTGGTAAAGAG
+
&')&"(%'+++$"'%(!*$!))*'#*'*'%!((++'()++&'#)$$%$(+%*##('*$%''#((+++**%(
@r640
GNANNNCNNCNCCANTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCANAATCGACCATTTCTGCCNTCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTAC
+
&!*")!)&%%%&"$$+)*!$*)$&###)&*&$'")%')#+')'$"##'%!)+#*+%+##)!&"*!((&!!#&")$*!($#)*&'$$*%'##"#+%)!%&$!)$''$#++$(&**#(&"$#()%$!"!)"'&+"#%"&&#$*!"!"!(&!'"+$+$%*$
@r641
CAATGAAGGAAACCCTTGATAAATGCAAAGAGATTCTTGGC
+
;:6#;+D;+7F.#5@D(?,D=AG:"/+<DA,)?DA#+5=->
@r642
TTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATNC
+
%64(A&"*:E!D<$H#&&%.@$B0=<@9C?*@:%:<D)D9D9,8=>&,+F"("-7A36C1&@?!EE,)@6&+$#G+!!'5E(H)F0'449?6>0'9AF#%304!:#1+?(.G/".>>F>G:"3D(@C3@1CH64<3.AC"#F/E?"G.<F/':H7'6?-/ED>:H=36/+(!+(FD"1(;B0-@C7=;G%71.75=@
@r643
NTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGC
+
%2%E5.("$)!260>;&/!*F8%#:0F3'93CG812B?@:/.CH,:=A:62&:$)<CE:?+F(*C@D5A<'#(>,'4%!)$%<A-;C4''A;B>'A6-,%B&:"2<@8+G&8G:CH<(!F"*
@r644
TCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATA
+
$4:)-,;=;.*H52C.*'BE.F):64CCH?;@A:(8'&?8
@r645
CAGCATCGGGCAAAACGGGCGGNCATTGATGCGAAAAGCCGGGGGNTGACTGACCGGCAGGCAGAACGGGAA
+
1=5"C,?8*!F.A3=*8G5&@6G='=$>$B&8D1<7E2/'>G%%8'7+->#52=<*<:30E>H;G#0DD+@@
@r646
ATCANNANTTTNNGNTAATANATCGAATACGTTGTCCTGCCGCTGANAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGT
+
''&''$("*#%'#&$(&)&$%+)&+"*)!&%"#$("(#%$+$*$)($%+&$%+$'#$#$$#!&$$'%(%++)%&(*)'#!"'*#("&*+%$%*'*!!&!!''#%"&++!%"'*+#$
@r647
GGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGT
+
)A"<+=D%3"A5H30!0845>%31!&97=8?DD+%$,C<!.H#..G?-;3><+%.20&8)&8$&%1$?H(/6902#7C<(9>/4?
@r648
TTGTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGNTAACAGGAGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATA
+
%!!+#%()!$#)%&#)%'&%#*$#*+)$$((")&$%'')!*'!+"++#""+#%((&!#+')&($$(!&*($"+##!%&$!(*$&$*#'%+($'&*"$$''+%&#''%*!*%#*""'&*(!"(!*!#)&#%"$)*"#"+)"&''#+''%"#*"(%(+#$*)(('$((+)*&'!))#!((%)#)
@r649
NNTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGANTGCTGCCTTGACGTTTCTAA
+
")D$AHC)(G)/5!-<"!2H=4BC?!)66(E(5<;".;',F<ACA#4C&'!,))E?!<'174E$544A>A;(/><4HC1DC>G?5A7B<C8-<"G4>390%&<
@r650
CACGGTGATAAATTATCTCTGGCGGTGTTGACATAAACACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAG
+
'%+'$!$"))$%!+$%&)))$%*$&($%'!%(')*)('"+'++%*#$)"$+$)%(+'%("'('(&)(**"*$#)$#&*'%'$%#"!)*"*%
@r651
AACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGAC
+
<)5;4<;1:CB6H0-G-0D4'(>*&(G%%H0;+@-@3*+0(+!A1?-B0"81A<;H;><(
@r652
ATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGAT
+
@@";D40(8G5#D-BADC17%/7$?D826"0H#$'G!>>G1@299640.$'6
@r653
GCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCAT
+
/@6%:E=*C(D7A;H$H*#+9)86+39/>;+0/(1#9EH4A-:F3<"5,>
@r654
TTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACT
+
F(B#;,(57>(G7CB;,E>60:<24!?1?<+%:C92A2?C%D0@
@r655
AGCACCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGTAGAACACTGNGCCG
+
'#($#(+$)')%$))%#&&()*"&)+)+#*#)!(('$#"*+'('#"!&"&"*'('%#'*+($*"(!))&#'++'")&!&*(%"#)+(!#""!(#$$"&#&)#!#&%$#"&#"&!"+'(")$"!!"+!)*%'#)(#+#%%!#'!")#)''*$(&+(%"&$$"#
@r656
CTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCTGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTA
+
%+)-7D6?97H?)6=!)F-9C4"*8DH;.12$02<>88/5482=0A69$9+<<@@6')H=:6C04?"15"38(($C:=B?/16=H@'5737=
@r657
CGCCCTGAAGGACCGCCANAATGCCGTTGAGGTGAACTGGATTGACCCGAA
+
G.9!31"6G,+0B35:=$@B#7#/<.:A015!7.C'-4>7@6?*(1/D/12
@r658
TCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAG
+
(/9/1'0B:D/)3G8G3.E="A)?!9B!,A)14B;+&3-/%/BF73,+$:E0$?.1HA(:$*
@r659
TATTATCTTCAGGAGAATAATGGAAGTTCNATGACNCAATTGTTCATAGTGTTTACATCAC
+
?F;@38,/2??'C-<AG;E($('<4>(BB05:@""?#7B@$*;0G=1-$6-'+C>527'53
@r660
NCNANCCTCCNNATTNAGGNCACNTNANGNGCNANGGNGNGGNANGNNN
+
!#!#"###!$!#!!$"$"$!"!$!$!##!!!"####$!##$!!!#"#!"
@r661
ACGCATCANCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGTGGCAAAAACGTCCGAGACGAATCCC
+
-!?8C;+%0!A>A1+,%E4:C0H8BD?AH8D36(.&=0C%=/'-)"C$E<%?7HB?83/C:DE23?D&#8.8A#D+6E<,A%B8#(;-!
@r662
TTNACNNCNAAGANAANNGCNAGCANNNTGAANGNTCNNANAANNGCNGNACTGNACGTGTNGA
+
$""""#!#$"#$$!$"!"!!$!!!#!!"###$!$#!!"!#$"#!!##!"!!"#$!##$!$!!##
@r663
TNTAANNCNGAANAGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAAGCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTT
+
'$')#!%&#%&"!$#"+*$"*#!"(+%'#*&+!%&*"*''#"!$)&&#$(*'"+"($*(#$)!"#$%"&"&("&*!##$!&*!%$#+$#"!#"*#+**&"'$*#!++&"'#*($$%'%'$(&$$(!(!))(#%)'*(((!%*!$%"%*'*$&&+%))!+*&"*%+%%'"+'%++)")"#(*&()!+%#*++&**$$&&#!'$+!&'$(#(
@r664
GTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGGACGCG
+
8!G$>6=#/#@0=2"F6A.@0,=;*//6G#E>//"8")1!F.16,-#<9.&
@r665
ATGAACGNTGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCAT
+
)(%'**+''#%#$*)%!&!*+()"#'!+)#!(%&!!'*+(+'%$)+!*(!!)+($&*&%%$*#*+&%'&))!))'!"+"&%!*'+(!%()*$'&"&$+'#&(+)#&)(!+%$+$%'((
@r666
NNNAAANNTAAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCG
+
"#!&&$$#%!+#$&*&&!#!!$+!*&#+&($*'('&#*%'(+!(*)'(*"!!%)*)()
@r667
TCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTNCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGNTCTTTTTAGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGA
+
(/&(;6D)E,7:@-$C=?18G>#9A6'2=-A%+/!+(=."3#$95.AG6G<%E?-#0*5F&"%+2&6<D#A!H.BB3/2;;2#B?&7('"H(8$71"HG>'/;F=3=0G&D&#@6F3>0D:A&&?EC'%60,,%53)!E7*$BFF@0#,./C#=@%'75*3#.
@r668
CCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGNCTGATGAGGTGCGGCAGCTGCGGCGTNGA
+
74?F+5@)0F2.'#E685'**C=AF4*A7?3",0#-<93#=!!)F)>7>9%D@D:8(?GC=;DH&GE=/:0#(D,#G+C)3&*2=&>BD"9.@4G!3G/=80=E1+CD3#0-#-0E-%E5!<,E5.*+DG*7#)4!8<"86&*(1359(!7-(GC(5)2H8>1A;399H@HC>&-!309"?,2/+'8@A)%2AA8':?8?G6C7.4;)F'B"5+5#7BH6$.4;#,C7)4<;302$FE,!#((?D'65#G,!@4&11H88?%!=#"9<%6@19''A&&>C)6%
@r669
GTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTTAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGTTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAANAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGC
+
21.%=7F1'=8(*29!?#6E:,/H$%(,,AD9>;81%.C;HA;@C)C'(?#F""?.3$086;3.&0981>A@AB6.2E,;'(73A7?"<*4><"H7BH"54)46#<+0+76*;+"2)"B)A$A(7(%-G1)/1GDA2>8.,90.&.?2!G4;;B=28ADE3$!/@+&8(7/(+3,129-2&)=63!10D*,$%2?E%<=+3$5#E/A!!69;6:4FEE%:C2<C>B#%2F0D'CBHAB97-D54!."1HH7+,=472,B0FBA>>2&+'8/HA?84B2F+D&%4D)5H"3'='H6D8G3'(F'%/(%0/;$EG#HFA#11<23FH0?!/"9(;7EA;
@r670
AATCGGAANTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTT
+
$+"#$*+))$#'#'#!'#&+%*((%)$&*()+(+!"($"'(#&*%%
@r671
NGNGGGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGAACTTTGATGGTATTG
+
&*!%&*+#*(!)(%$&&$#!#%(((!$&+#%$)+')+%#%))))$'$*#(%+$&'%))&"))+
@r672
CTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATNGCGTGCATCGAGTAAG
+
2D?=<$1,;*%7E%>9(=89AF1;!'H@$3+9%$3C#%*!)!63;GC?F"2>#-AAHE?BC=
@r673
NCGNCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGCATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGNTTTCCCGCAATTACGCCCAGATGAGCTACTCC
+
!%$'$++$')*'!#((#!)$(#+&%!#&(+!#*&'(''"$$+")*(!)(!"#(#&'#)+!%&(")&("#+#$(*"#!"'+&''*&"&*++#"***%+&$****&*!)%(!*('*)%&!)*%$)+"%$%*!)'#%('!+%($!#(!*!(&&"$%$)$"((&#+"))'"')*(*)""*!#!$!($)!$'&#
@r674
ATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTNCCGGAGTTCATCGGAAAAATAGACGAGGCACTGGCTGAAATTGGTTT
+
;$>4?:&.;+6;20?)332E+8)H7?61>"%;)$9G*;"!#"@;G6!,*;)!(92AFB&7H(5BH?'90FG8+;?$5@(G>*FE9/%2-%D<D;0H#6@0
@r675
GCTCGCATCCTTGNATAGCCGACGCCTTTGCATCTTCCGCACTATTTCTNGACAACTCTCCCCCACAGCTCTGTTTT
+
)&$"++")*"'$)!&!+%*"*%%''+'$((")&**($"%#%%%$**$'**%'$+#')%!+*!%!"+'$"(+)!'+)(
@r676
TTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGA
+
+4/*1&688A09@C487-3:-'3)<#'50.DA843::F=H(%$5B5B0".H
@r677
NGAACTGATGAGCGNTCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAA
+
'@+%A;',0C?7?D*B&/.2??1%-F(&<*72B#;<6*:.&9'#4B%CE$#?-?4?8H?;7FB><!5"#,5:H9''
@r678
CCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTTAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCT
+
$H&18?5C9A5,#E!.56,;:6H)#=<?602(.;'37/0'20)*E*D&?)?&BH%7254*</90$,&'9?'20.&8*:AGFEF#-/)?G&E3#2'-@;*A.@'F(5B6()=B;2711>9
@r679
ATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGNTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACT
+
@>F%/?9/!8"/"E80'>D;F45#&D'@&@C>+-%!;)F'=3)4":6A63>,2?0A$G-,H#)!:,#5:D)*"7%+<H.E@,'G@200/A0=,D<F-%/BC'B"*B!*HB8)-<F"",3.,F:0)<B+,G*?F=G,A&5#2/#D<9'#6F.A(<6.#
@r680
TTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCNTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTAAAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGC
+
F;4=/#3(<.!/@B.27C")?7-C=C4#FB$$B$,/!@"3:*,=)@2E6'8*<G?%"(.+#C0%1&5.#2:734"<-E"F$505F65B-D5*,+8F4DA@@8+@%B(1'-@9&78@;D&'#4&.5:@;%#6,23-?9-=$F@!F6H'<GE<>H;9H9/2E*,?<:$?G.=).%>F(/&:3%%G/A>HA29A0
@r681
AAGATGATATGACTATCAAGGCCGCCTNAGTNCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCC
+
$0/,G%DF;6959$B3./!!3."'F;"D32H&/(B@%1F7.F1/C$92;"F8$+@"G@A!,&5?*(C0@=CF..:2)GGEH)0:A(?@@GC@04"(;+-@G,D*);5*/=9=0
@r682
CATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTA
+
:;(-;$#F6!5G$%;AA"*.<)@BD29::<@>7$2D:CH+G6(&?H:26-(BH,#+"05D$A$D'B?7EB!2'CC-DD&&<.$A%FBA(%"<C6E4)>&,5E=G.2DHF#,4('F+5(-!%H)>".64G&-?:.((+(5G82;F;#7=.*<
@r683
NTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAANCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCNGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACG
+
"'F$(5"?1D2?1?0+4$7*B34-G61A:*4B0A7$C77:</0#G7/'&B#"3,5G&H7,?5652E@8!/B!32-&(202./D:C>)G3$<!%G%D?;!H3A>$@?*?;6&7C+E*:;'2?1:88E1>461CD3!/9%9:!?G<H/%A9:A.;@(=$#/F?"-)75-6"&56;!.76&"@4$&*A*:5-92D"F$2*5C$?3>::0
@r684
TCGACAGNCCGGANCGNNNGNGNCTNNNCCANTCTTNCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGC
+
))%$(*'"!*%%$'('!$!!%%!')&'!(#)**!#&&+#*'%#!"!'(#*"!(#($&+&%(#'!"!&+'+%)'
@r685
GNANCCACANACAATAGGCTATNAACTATCTGNTGCAATTTGCACACAAGGTATCCGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTANTGCAGCGACGCCGGGGGC
+
!$'"'(&%%$*+#)+))))++*&%')$')%+'!'")(+'++('#+#"$(*'+#&++%'#%*)(!*!*+*!$"*$!*%'(!+#+'&#%"#(*"***+'"&)!%!(&+'%)"+("#"'!+"&%$()+%!%"!#"()!##"%!+!&(%&+"+(!%+"#&$"$"("$)('+*)
@r686
GACAGAGCTTGTGGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGAT
+
3;0@F;H+,#E?8+F"-%+BE'@*>+!6-%!D<0G%(+!4A$/>#88G-9695@0.)/H&,F4E
@r687
TGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCNGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTC
+
E)-DH#,-9E""B'A.(&D@#4))A5A'=7D9.*:""#B?B--?1H(!,,B1"4D9</6F,64&/@3%&!?E3G.%D,9*F8!(#5;2.,=$G.,($H7BC1F4<H@C("B;",7F!1*9-&'G0'5+%E1
@r688
TTCTTCGCGTCTGCCGTACTCTNTGCCACCACGGACGCGTTACGNGCCACCTCTTCCACCATCAGTTCAAGACGACG
+
>$26@(9FB0GDD"0+F8!=28581+B5D'5"H:5+)G.+H9>B4E<7'1@=$F59%2+'H78"C0/;,FB98B*%D
@r689
ANGACCGTAAGACGGAAATCANTCCCGGGTATATGAAAGAGACGACCACTG
+
&!#D=F00!E-)-0:95#F<",0$G(HE&@F(&5:F+3?2'C7A,E#4"&#
@r690
CTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGC
+
B$?=E>!55+B#$#E9D?A&AFF1G2"8&/=+*F>H720B%8CHB33<)73H<D!H1#%:"6;33##"
@r691
NNCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCANGACAATGAATCCTGTACATGCCG
+
'&,"1<(+;GH"$9!!2A&EA5/6.@51DB>(425,%!/A-A--7C=3.66#H968F.B8+((((-!'0D00*B3;BA:,?#0""#,+=59D8>97&0>$$AHD.#C%$/);+-),42?-AB'
@r692
GCGTCNTCCACATTAAACTTCCGGTTGCTGTCTGACTCCGNCTGTTCTG
+
&%*%"!%))$#'!++&)$*)+$)+#)%%'+%"*!*"()''(#$""*(!*
@r693
GNCNTTCNNGNNNGAACCGGATAATGAGNGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACCGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACC
+
%!&%$%$!#*#&"&"##%+&""+")**&$+%&#()*()$")%!'&%)*&#$!)(+'$'*+%"*%&*!&#%$()#%"%)#*#*)(%"%#('"&*&!%(!&#)%&(!!!%('((!%'%&+)&***%$!+*("*%+"&(#&''!+$+!&"'&$*)(*$+$$$+'(#$'##%"+*#*"%%!"%")&#*$)
@r694
NTCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGA
+
"/#B7"*/;+7G7A,91&?E/-A&$;*5!2E'#F2(?.1@*24H6?1H.'5)0H35$!'C'#7'F*+<'&&
@r695
AAACAACAATTTTGAATGGAATCATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAANATAATAGACTTATCGAGTCAAGAATCCCAAAGGGAT
+
1FFG,0/'A<3H,!*(4,.?B.460E5'/%-.404('?B?:6/(39$0-50'#2!=E365*).)&2)(=F+H-.A7F=:C?'7(:/!E9FA0>!%.6/F%A5H3"GF5
@r696
ACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGG
+
-8)G+<=4C<D7"+F"4'25'-(A965-'>G?09):6.1'#E%!=7&#?=C1;%F"5BE<(2@:<
@r697
CTGGTTNAGAAGATAANTCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCAT
+
F1+5<97<@FE>+C;39<:<G&=0-%E730C2>-.)+8+((%%<@9%4.H#9G=;EC+7D2'G%&/<3C?95/+@2D+(:'&7F=
@r698
CGTAGATAAGCCTAANAATATCACTTCGACAGAAGAGTTAGTTGACTAT
+
"1.F3>+41H;7*5++;3.=)/'D*BG@&0D.8EC#!.F0H=//%=3$&
@r699
CGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAAATGTGGATAAACTT
+
@1<FFCG"8"10":33+AD:3;DB>*<%<7@,?5B.%)E9!,6;60#=?A>9.F?/01@+/(D(7@)"#F0?D*8G%$*@1.3.7$-3(4HEG4)?)(1*1
@r700
CTGGCGACACTCCTTAAAANCCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAG
+
),)2+0D.<<:<=&&?-900)(,)5.,HC?@@E7!5@G:8?=$'.'":BG"A=@3DH(9@>'6'=$.H!@5$0-$*F><;#?)B1H>$C9+$.668#.?9GE,-2-%!
@r701
CCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCCCGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTG
+
D%)D)*2=?G+&7/13"&828>&>!:!378G0$--7CB6=3%>:!;)D3A9+.'A<)'.*)9:(850/&%',;?1FA"/D)5.6(.&D72,EF>#72DC;A-:3H*$,1!H7:/0A$@+9.@%/4@B/@-F7/'*;B:@@;</?=267!F,@8GD0.4GBF16D<47!=A%#2CA?BE85G*9(+%?H-(&8
@r702
GCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCG
+
D::8-->=5&!C%*%".6(=-G.;G&F>F#.)5-2B2H<%!(-69'@0;+%?:/38-&.HF1!>,":*H(F)%??'+'G";33
@r703
TTGATACNGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTAACGC
+
""!)$($#)+%***!$#+$+&*$)%*!(#$*+'*"+"($#(+&"#%$#*)+#%&#+%+'
@r704
ACCTGACCGCTATNCCTGANCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGC
+
A93EF+*;D/D4'++G:G&;1??4HA7,6?AA3F<C=*2E%8C0+3>G2&5@AE267EC@0F=?EGA2BC6%9/6!?0<%?':'1G%40A>"*;#&-!C7A70+62;5+'?D@$F04BDA&8*:>-#
@r705
CTGTGCGCCGGACGTTGCCGCGCNAACAGGCGCAACAGTAACCAGCATANATCAGGCCGCGGCTAAAAAGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGNTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGC
+
53:46D$'!+!0>7=7?5A2<#(+,*$F!;@8"!2F73@::1E*</(&(*"B5AEEH2E'77A("$GD)B<.,*9&'60-:B<9D8B<&4G.<BH/4,8H#G0"!0H#1;<BB@C!)G@D.$4'',G;%%D/'+2&)$*-52+$D#.<G='(E++=2!B$$!!<)0!&.'C-8.4+)HE6;2:@%$6')=,&DF(0)D)G:
@r706
AAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATAT
+
(>;5*:7C61.0#:,5(;@$=F:6#&35:?B7H-!*#4&<+:@7.+!4H>G"3>6)3<2
@r707
GCANCACTGCTGTCACCCTTCTCCNCCTCTGTTGATTGTCGCAGCCCGGATTCAAATG
+
&%$!&##)#+%$"*&$#$+*(*&(!%*%%+**(!+&!+"&"#))+"*"!)#!)()$#!
@r708
CGCAANNTGGNTGNNGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGA
+
)%*"#%!")'"%')!*+%+))&+((#*""('&+"+'$+*#***)*!!$%++))"#$"
@r709
CTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTANTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGT
+
BD47H5ECGFF#B)(2@@.0%BD<*C&B:?FE0(-C1/&"$"27=4<9E1!#;2<DF*2".+DC+,/**F/%!,#4:419'BCC20%>#C76(G5$77"-6?H,64)0%04>.3HA8D7G#EH'23#)3%0B'./?')40,'@BD/8&=D5'HA='=5.H,D!$C/B9;D3G8(!&74.')%8(1%76!%C4'4)31=5DH;"/3!AAC+4A%.6@$>$-0#F1(-#C:#"@)&79H?F1,8B!3*6;:E?B.(
@r710
AGGGGNGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGA
+
('("*'+(!&%"%"*!*"*&()"#*)'('*!%!"$#**#*"$!'%#'&*$!!%("**"&
@r711
TGCTACACCATTGCGTGCATCGAGTAAGTCGCTNAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATGTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTNTTT
+
/D'0/$5->!%?<4:9-.',4)1!"G2,13C.4(><4H3DH%+:=,"-##7*A5<%=FE&218B34#,.>3?='8?7/G11<.=23:&(1'E06?)!,G>///60?!7?E-7D"55$"E%<*/C<C8C3=2EGH,'F0A24D5$F.+7)@#-"$A?3E@1?9F#)$2)@.29B<3>114B!&$8%!5/#(60E.F-,H"**'(34-C&8?=.H4#??H3<9*$!3+G>/;559)"@2AB!BFD<C5;B:7>671@<<@;)1??:5<,92#E1D+9!A-<#63+7+*>!>/A80?:3BB.D!&(+9((F)<.$<2,B;.G05D!<*?:)C<.?6BF*0GH/8+;B7">BA%+
@r712
GNATNCGGAGNCCCGACAGNANTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAANTGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGANGCGCTATTACGAAAAAATTGATGGCAGCAAAAACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTANACGAA
+
$)'(!)")'"(!)"'#&#)(%*+++)%+&+!($"&##$(&(#(*&&&($%("*)#*"'!%%(++%$"("'%*%#%#''!!%(!!*$)!#!("&"+'+#*!$($!%#'&!+)$%'*%##""*'%!!&&($!$))+'$*$%+$'&'!'!!$#(&+(*$!*!+"!%+%*#(%&%&+((*(#&$"$)&*''**'(+"&*)!+!+''%*"(%(&$$)&+*+)+!(&)
@r713
GGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTNATATCC
+
9,'=D"DG;*%.4+("3$4H?-<@#2C?>$&!<0G2&(70'B'B;42H$:$=>"A%B*6>G
@r714
TGAAGCGCGGGCGCGTTACTTGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGNGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGA
+
24*<@HG41336*8E/7>.,&HE@/:.GD*4)..C-B/?&7H@7&>$6=D#A72@#3B%A82=$:?D.B16?:"8HE<?HC>0@&1.*,?-3E0C!=>8&+>B.228)F$@CB.%13
@r715
GATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTT
+
C?+.8+@9#A3%3<9#5%0-#1<';#.;;#'?!%*<(/6GF<$H$;@=6<6@2#%3$1C2+4"?!,<0&
@r716
GATTACGGTCCTTGCGGTAAATCCGGCATGTANAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCCTTGATGATGCGGGACNAGCCATCAACGCCCACCANCGGAAC
+
=+.6'C;%+C2%D9D3@E>"=/+2;H05#*G#<C=-+C.F'?A0-5#<$5C3B,=C%8/!<=&EA"(>.8-<>CF274?GC<H'*+0%1@D+(E@;<.?#2:0#$/9@B<<4H=:(*21F,&85
@r717
TTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGNCAGAATCGCNGAT
+
'602H+).)$,H"@,+B$5FA,(!=5H%@8E)""CC'AF-D<#+3+.<$'1!/*10,5:.G2
@r718
AATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGCTATCAGCACCGGTGGTCGTGTGCTGGNGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCC
+
8!0E*/B<'=8:+;%:,*B+#'78(>CF2/B$?=:+((#$@-,"@C#G;>%"-F?5F$2>8:>;0137:>3-D;7$F)FE'EF)&DA"CB995A:<,)<+6@70(:-C23@E0(C%<9F#:%:0+$F,/0/A>"&G#D96:8?4,<#E0G&'(24>D4@B70+DF697;(3#/BD@G??B!6F(/H-(H;1&.A*A,2%>>=)1<#!7()F,/%".;?(@>//$6(8/C+-#C)?";8885F+"+1/?4(.1;8('</06D/$>3)HCG@./&+*(1D>=8:<
@r719
CTTCCAGCTTTCTGCATCCNGCCAGCGACNATGCCATTCNACCTGACGAGAGACGTCACCTAAGCAGNCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGA
+
")'*+*(!"%*")'''#"&#$$("++$$(*&+!&""%))(*!&%'+&)(&(!&$$!'##'!)!&(+'*#*)#)))'$"&*$$!+!(''&#&#$'!'%(&"$)%!#&&*%)$)
@r720
GTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGT
+
.19"*!6(.$0E"8$GD6>'92+(B/>G.H*:&,=?$E,-4HC"!CE=C2
@r721
CAGCGGTNCGGCGCTGGGATATTACGTCAGCGANGACGGGTA
+
?CH9B>AF)<&7A#3&3>&29#E>CF0?2=B'9D9:)?)$&F
@r722
AAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTNTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGT
+
0!''G'1'<*6;E)'-,9)D@541'16)>B''8;8106>=?0>.+=C&E<*5"2'/%';4#$'=+.FFD08=9=8(!B((>%FH&1HED:+*3%%EAHEB9':)$<)!%@?>'$A>=A5&%/(-610:)G3
@r723
GGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCNTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGC
+
/.H"?,EHE31;A&D:H&;:!/*!#8$8/$67;9)37H43F(C79#=';$>729754+8."1$5-+>!((,'"<356?,77";3&#@A!>(,=37*BCG'>H)*=-;<"D*7"BHA>,$-8C"#+.-/2@8(!:%D0;E7-%0(':1+&D:<>989E.#3/-A7$9B:0G$+2
@r724
TACCAGCAGGCCTNTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAA
+
"*@>0>E<-/,(8#0&00$HFG>H0)=>(5.=#BE8@-*,B'<4@<7'D#2',=D771D=&-B=02+D!+2"B727.540@13?@3,4D!.:FH9?F*?5E2A<5/E$,2(7@/"41<?%7)B!7:H82=.-,9'1&&!:=800(!.H0E;
@r725
AATTGGGGGATTGCTATCCCTCAAAACAGNGGGACACAAAAGACACTATTACAAAA
+
AF&#-$.//>:3%9D,C/)H4;&+)?4?%4..=B?>'$=EB?6&=,)3<0+/H;DC
@r726
ACCANGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCNAAAGCCTGGAATCAGATATCTTGCNGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCANGGTGGAAGCAAC
+
;<#0;-0%EA:)A&%+A.84+%C3+=5"'.?,7B>G<B*+#%=)?@)EG171FA-'+D/C7)H!<H)26E2959+5)?EFD.@2B='(,19AH5B:)-045,=#)/G=H#>:;0<0*F?::
@r727
TAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATG
+
<'8A95'/FF0B.G?2$0:*8#<)/D:"""(B1%1DE(F#('33'--+A?72A'5G@@E?H,G88F77@0.>%5>
@r728
CCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGT
+
H/E@-B7E/5D/@<B%C=@BG2H6FA;;D0H'50F$%BB.3;++#+3?F/$E$EG.=.F7!5,@-3+<
@r729
GGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCG
+
>@,G,:@:3E9//;.+.C;(4FGC3&#28"%7A&&3F8(:*HC%5
@r730
TTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATA
+
B*'-<":&G2#=.007:,8G>-+"1G3"E(%80+.+-"&(*
@r731
TCCCTTTTNGNAATACGCTTACTCCCATCCGAGATAACACCTTCG
+
(*%&'')&")*&'+!(+(()*)*)")!#"*%'*+(##+"*)+'"#
@r732
ATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATNCAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAANAATAATCAAA
+
%+-@#CC)3B!:;<:GD:1:G<5)#-)%1:'B.G>:-(95&0/B1FGE?,<$0FF,1,GG=)C4D)-'/11H<&H9,4A=:%D*C-5"5EC*@="8@GE0((((5+1')BF8&
@r733
TGTTTGGTAGGTGAGAGATCTGAATAGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAAT
+
D4%19#&B(1B7)E3@9@0<1!+EH#@,H)#!*=($(8@8$BE64/C1D"!F79.:273;$;5/G3H=#H!F
@r734
AACCACTGCTACCCGAACACGGCACTGGTCGGCGTGCNGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATNAT
+
'*$"+!*$(%&'&%%((&*"%)"&'#*+#&++'$#))%'(")##)&(')**"")!&#%()(&((&!'$&%%(***%"!+*'%)!
@r735
NCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACG
+
$**$(+!('!)*)+(+*!)*#)!+#((#*!%#"+(()&$$"'+"""!&"'%"%('%''"'(%$
@r736
NCTTCCAGCGAGAACTTAGAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAA
+
#%F:F.E,?$094'F1.D?=*#C"C2"A565&.!,<=A6:*%8F;$=EG*(6"#("#D/&7"7
@r737
TGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAG
+
?/&3C.*&E!>&5!G*=BB'-G=#1'"'2F<%./+D<(C;HA94='.2,&&/>
@r738
NCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTC
+
"2.DC"8F?9=#??30G53'*?;5='!%45!$:3!CD0:<#+;FF(9+.
@r739
GTGCGCACCAATATCAACTGTATGCGCATGTGCACCGGCNCTCACGGCTGTACCGGACAATGAGTGACTGTGNCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGG
+
+'&$'"'"")"''&'#'')'#!"%#%!$+!$(+)'*("#)(($+)%(%(('%)+"+&#*&%#!!('!)()+#"%"#$&!"!%#$!)'!)$#'*')!'#+#"!"!('&$#(##((+&!*))(#
@r740
GGNNANNTNGGTNATNACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCT
+
**"%#$$##))&%(!"+*($*"'"((#!#!!)'(+!)"*#+()'&&%$+)%+!')"*'%#$$)+&*#**#$)))
@r741
GGGTGTTACCACTACCGCAGGNAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTAT
+
@<=9>A"(32G(+"$"+1%9*14!2=>,5!<+/G,48$*&)D#<B<2.H;192?,6H
@r742
CGCCAGCAGGAGCTGGACTTTACTGATGCACGTTATATCTGCGAAAAGACCGGGATCTGGTCCCGTGATGGCATTCTCTGGTTTTCGTCATACGGTGAAG
+
?'HE$?A$(1%"%@"2:""(!!E1:A;.@B#=;1%:(&-'HC:7BA"6#;@@EE"9&(HA-AD9";C&D5H9ACC)/H?'6E8>3&07'?$E.4@D@=2!
@r743
TGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTNTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGCTCC
+
)34!C@*C9CHGE'(6:6@)!'!$8=(&%@,=.$;=21"<!E9%(@(61)64G'&D(=;$A+,@5#40E9FB=9@%@=7(":",-(>*;5;&4A#4)EEF>0D:-:B)-%2:3G+/)%
@r744
GGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGC
+
B=.%?:$+47.7)11;.2;*05GC964/1'2=#CG%;C!D72!F88"/59;.>=
@r745
TATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCAT
+
6B4(-:1--+#/F2A>3,),"40+/C:#G>/G5-B>=;1;5=?"333D8<!#3FA(G')/>?
@r746
NCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAG
+
"%""%++*'))"*#!('("&#%*&#"%#&%&+#+&$(*)&#!*)!!+%++$+*+$&'%*!#*
@r747
TCATCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTT
+
9+7#=>"*A8GHF&1"9@&?<#496'*!/A4!D$E.$79(%9#)<=2C"@)B6E%>:
@r748
TGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTT
+
B=F?0597B;8'9E/("<-,@2,86>,#'94!H$9>#;8>!2);D?@<7>)%2H!H*5B?6,C7?8C8-D6":D=C&+;."5:B,
@r749
NNNCGCCTTANTGNCGGAGGGCGTAACCGACAAGACCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACC
+
&''!*%'(*#&#"+'*"(!("&)**+*%'%%+!*))+'%%!)*#$$(!''$)(*!#!#*%+!+!')%$#%$%&*'!"$&!#+(&+%!"($)!&*
@r750
TCTTCCTGCCTCCAGTTCGCCGGGCATTCAANACAAAAACTGNTAGCACCTGGAGTTCCGGAAACAAAATT
+
?)9$."&B@"AE?4/#&1"=/<?>C#*4''G'*C:0(24+3/C'.2G&(1H@<3'#CB7"*.45&?",'0<
@r751
NGNCAGNNNNATNCCCGCNCNTCGGGAANCGNGCNACNNCTTGG
+
#$$!#""!!#$""#$"!###"#$$##$"#!#!"$"$#!"$!#$$
@r752
TGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTT
+
,0.)E9?A:$E2C04'8")4;E)95A.*32.%H(,;1&67DF:C@@8D0HE0):#6;5'3'1888"049H6:6#F%BD):B1,B9>,//?&8,.G=78!D15)-$2G9FB'5$7/76
@r753
GTAAACGATNCTTTGCTCGTCGTAAACATCCCTTACANTGGTGTGTTCAGCAAATCGTTANCGGCATCAGATGCC
+
'%##*!)!#!+!!*!"#'#$('(((*$&)%*%$!&$&*%#$%(%#*%*"())&)#'!')*#%+"'(*!!$*(*('
@r754
ATTCCCGGCGCGTTTATTCAGCAANTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTAC
+
<=$&'+%*$)+HC$DB8)C"428C*-:F%6.'',G::/6B>7//"4''<9E<03/H71C8.9*808>;D'4;,1HH?%
@r755
AAAACACATTTGCACCGCGAGTCTGCCCGTNCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCA
+
H!=CF01E**!4+@18)3!'0:),A7#=/-4--13EG8EB0<$B:B;H@$EC,8<%>$+*@7;*0750!>1=4G?%EGF6/8F&*6(=GC+6A=E1HA=)+(167A$36D;
@r756
TGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGACATATTCTGTGCAATACCATC
+
<<=BAE6!.3+3+)'*427B?9=D>9H7A&1H6!H9(#G'HB"!;*43="?46+>3?&@>(:B>
@r757
GAANNGTNTNGNTAGNANATNNNNNANNNNNAACGNNCNGTTNNNAGNAGTANTCANGNGNNCGAGNTNNATAGNTNNGNNNNACNANTGAANNACNNCTTNTNTTTCNATGNNGACCNNCTATCTNNTNTNNGGCGNTAAANNNGNGNNTGNTGCTTNGNCNCCNNGTANNAAANANCNNNNCNCAACTTGNTNANCNTAAGNACTANACNTNAGNGCNNANNNNNA
+
$#$!"$#"##!$"$$!#"!""!!""$""!"!#$"#!!!#!$$$"!"!!"$#$"#!$!$!#!!$!"#$##!$""$!$"#$#!$"$""$#"!$"#!"$$!$#""""##$!"$#!##"#!$"$$#$$$$!""#"!$!#$!"""$!$$##$$"$"""""$"$##$$!$"##!$#!$"!"$$#$""!#"$"!#$!#"!$!$""!$#!$#$#$#"$$!#!!##"$!#$!!!$#"
@r758
NANGGCGATCTACATGGCTTTGATGATATCCCGTTTCAGGAAGTCAACATGTCGGNTTTCCAGTTCCGGAAAAC
+
$!''($!%%!'"*(((+")*&$#)$"&"&$!%(!!&#*&(+*$'!&&$&$&!%"!'%#+*+$#)!&!!($'+!*
@r759
TTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCNTGAGGCAAACAAAACTCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAA
+
?*>ED+:8B2EA,AH#F+#32?=&#700G2F9@=B+08)?>E#*-$!%".09"?(&%&E@4FB9!H.FB1,F'"+C3'C4C8+,.A2/1$;.)
@r760
TCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGCACAACCGCTCAGGCATTTGCTNCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCNTATTCATCCGCGACAGCCGGN
+
*>)69-.CC)$4?C0;(AFG93';C2+>D59F.??&/2G%D-?03.8#?=,C-$--C;>*#4&<-'<D4@E7F-1#"3.BB69(7#1*.=6)<=)>D!!G:E"<20G%),$=<BH?H769+@&,7C*C+$($6FD3F3$?=;.%<9@7;-$;F5;70.#F86D5"F;/<B*D1/G>(8+A+ED%/1<E99(::%%A1DF65;06.A"1G0'D#C.'%'#8/!G6;'G1--*5(+(
@r761
CCNCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAG
+
(##+%%)**"#"'')"%*&)"'#+$%#'&+*"($)%$"()$+&&#**"#&
@r762
TTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCT
+
00?>A$1GA+/G&.BD?G%):=$3AD+02)-<3.477'874")5'5:-D?=*5B5G)1//G@G$*"*25$+(?-'(005.?1/04HE@%?&8*A&+4+/'9:98'?D:"#-<??.GD:!(33.A1,$8":G2;+D?;
@r763
AATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATT
+
G)3'9#8%0H(+E%G,0##!8;(@.!;1:803'5$.06'7%9E)5E@4E7HHB,"9+8
@r764
ACANNACNNNTNGTNGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTNAAACATTAATTTTTTATGATAAACAA
+
$)*&$*#"#!)$##!+))++('#'*$%")!(!$&''%("+$("%$$(!+()+$!#)&')(#"#*!$"#(#%(**"!)$(!#('#&'+!$"#($*&)
@r765
TCGAATCTTAAGTTTATCTTTCTGTTTCTGNTCCTCTTGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACT
+
%+#*"$))"$'!+("#"'#"('&%!%!$'$**!'*'&&)"!)!#$#!'!#(&$&!&%"+#&!)$%"#%+"'+'"+'#&(&!)'+)""
@r766
NACTNTNNCGGAGAGAAAACAGGATGCCGGTCATACCACNGGCCCCAATGGCTGC
+
'))"*$(')%++#&+%%+('&&"'+#%)$(!%%$##'&!"*)#'("&$#%%!'*'
@r767
ANGGGGNGTAAATGTNCCCTNCTGTTTNTGGCGTCCACTGNATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTAACGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGA
+
)")&#&!&*#%#")%(%#%)%"'"!'%!"+%!'""&'#)!%&(*%&+%'$(('"'++&%#*'('&'%$%$$$('++&$"*'&$+&*&"%%"$$#*(%!*$!*!%)(!'('#(!*+"(&('%%!*$&!!!)*"""#)&'"!')$$!#(+%!'#%"%"&$'%#)&$)"'(%%$+&"))*##(!!$*&#(+$%)#!+%$()!%"'#)
@r768
ATATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTT
+
5:GH*</H6H6)0=HB;>9>*76',&4+#D:BG>%,4B>6HD>"@5E
@r769
CNTCNGACTNNNGGCNCAGNAGGCACTCGCGACGCTGGCATTATCC
+
'!!(")"'$&'!#%$&%*$(+)($%*)"$")#+'&'')*(&$!'(!
@r770
TNTNANNGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTCTTTTAATAAAATTAAGGGNTACTATATGTTGGAGTTTAGTGTTATTNAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTT
+
)*(#(!$*+(%)#$+&)$#")"$"%$#)%%"($'"+'#+(!&+*$#!!*!"&+&%'%)%!#$"%++*!'"("&'"&')&!&+%#!#+$($+"#%$%(#*&$*!+%)#'#'&'!+(&!%&"$(#&()!#%)&$+++(&"+)+$!)++)(%##&'+$!$!+'$"(*$!&(&&)%)&#*'&(!&#%%&&
@r771
AGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCC
+
=@;;161@01#B--1C@5&/8&GA:26F/:7,91)>?.4'/40
@r772
NNNACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGTCCCGTGGCGTTGCAAATGATCGATGCANAGCNATTCAAACAGGTGC
+
!&!(+)()!#*!*+)%)$*&"!!$%(()!&""*(&%!&"(+*%&#!)'(((%&"%)!+!&#!)+#%)*)!%(*&"#(!""#(+***##&%
@r773
GTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGNTTTCTTCGCGTCTGCNGTACTC
+
8/9+4;!(,"D;29++,')F!3B1070@$+GE1%='H:*?+(B9)?=F!EH*CA+8'*366:CE;4ADF#828EBE!.#=)9@>?</1.<B-
@r774
GACGAATTTTCGACGCCCCATAAAGTACGACCACGACTCGTTCGCACTGGCCCGTGCC
+
4?$;1<:43,44&=@H=-$(6/2=$'",94.B7G4:6:69(.?3*8BB?$9%,0%,93
@r775
GACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATA
+
0@G/4!@3!),..4)@7>>>"D1D>="))9E0)%=>E@-7<'<
@r776
TGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCGTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTAT
+
)9#((&B7F&5G90H,2*2?0@7BD;;09?@0?E/%=)'?#(,:.,?EC8BGD,3AD"9,B:)5$D1",-&G%;?$@5&+A;@)6%86D*G32.8'9&@#$&=>%1>#@,82%:90D-7'2,/+:@=:729<218,$5>5
@r777
GTGCGTGACGNACATCGGGAAACGCCAAAGGAGATTATNTACCGAGGAAGAAT
+
:BB(%$*=D'D<;$EA850%5*5'D@2#5<F?@7"9!EHF9?A>:,9(+$>);
@r778
NTCGGCGTNNCNGGCNNCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCAACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAA
+
!#&**'%*&!'#$*#!!+!)%'$##'+*##")*&#*("+!"*#*#&"+'$%!!!(%&)%)"$&%($&&$(""'!&#!$(!!'#%(*$*)!$*'%)&$)%!%+)$*%"%)*)%$#')!'+(##!($($*$("&!)&#$%(%&%*'
@r779
GAAGTAAGCACTTATTCATTAATAGATAAAGAATTCAGTCAACTCCNTGAAATGTTATTTTCCTTAGGTG
+
2#-"EC@)2$0==&,,-:2:EC8;@>.G&)671:<C*6=>214(*F6C@EA)3&G<#EG"93(B2=57;8
@r780
GCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAA
+
.+',<GG+/;H,@F@!H>>(H*>.!+/29)GG1431AB6A4"C."++80:.GF79()1
@r781
AGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTNTTTCCGCCCTCAGCGTACCGTTTATCGTCCAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGAGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTG
+
A>&*F(8B.A4,8'DFD:&D@7A3)CF#.(3>$):F@.,+;(3H?D!9%A</D,F7>;)&#AA81EE-@BF=H'57/'/H5F@=%,/==9*<>@,G8>1-:-*E745=9&")FH=%8E7:7*H<'+/(/.A?<7&<@9#)%9;2:-&E3E=0,=<<?/!0+$C<@<:%<5'?8D*E09'H+)>=3@E/2"40B@C&-(945-?#&6'1":-E&%5.FE97,"F4AA0
@r782
CACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACG
+
@09H&D2A&(?C@&C$G((2?1B!?%DB,8HC4D>2G5HD)85D!+F.>6,?ECEE=?7E.H?)3AB>D7/
@r783
GCANNNNAGNGATGACAACTNCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCNGCAGCTGCCGCACCTC
+
&'&%)&')(#'+&+#)+&(!!#)"%!+"(#""$(+%)'(%&%"!*$#"&'%+)*()'&'!&%$!#&&&+)#+$*'(#")%'+%&(*'$'*$+!+$'#'&!'*"$!*(
@r784
TAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGC
+
32F!9;H/45+,((323&A$>B(+.8?.;8#>+4E03F63%F.BH72A=$#,"?6!9G$77?9&,)G-B+3"A8'7"#,3)F!=A1"F0:
@r785
GCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGC
+
81;/(5B69>2H8FB'GG9='3-3*%!D5/GB!8'!D/*?5@)5.7!=*'64"..1@='#/!'**
@r786
CGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTANCGGTT
+
)(E/>D!E!">1"H%+B1:5G67C07<-<!=195*D4@;>
@r787
ACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATN
+
A&0@./DA="&4)3)A/&D2%%<@1B3#3B@)A)BH86F,)G?@'1@..-BC:@/#3>#-+*:,&<C086F!CE9!
@r788
TTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTCCCATCGTGCCGCGACTGCAATATGG
+
3C@19?66DD><#3FF84>:>(C@AG%,<"F>+E(/9<7H0A:!1.H2'(#!E0EG$AE$:7;C0,)67;C+D641<$
@r789
ACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGG
+
3"8CF%A>:&)3#:%,/-=*?CF5,),;=':6(@.&4,E'D>0--58#2(@G3%+794*4@E-D.'?;<.9$(("?@%?GCF*0C1H$,&<@%8D4F>1A9H184+:(2$+2F<A/(<;8279&D40,'&E#32>1;=;/)@2*#='%C@>"(93<,#"CG)H-(A-*?E?=/-.7B/.<D!:$/=1;-#=F4$<',<7>-
@r790
CGGATGNTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTT
+
D4&3@$&,3&@5!(E=B<+2">51>.-!DC.!H)9.>HAH(<2@3G+=/=+<2:B("6!/.BH!/*4ED76F-#.&@#?4.3H(:6HH8%1B+'?C-B)D43#.30:(A->>8
@r791
ATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGNTGGTATCCAGAATTTGTCACTTCAAGTACAAACACCTCACGAGTTAAAACACCTAAGTTCTCACC
+
C5#?(*!*6F-0(%=&<;8*,'*&?"D)F?%2*;@)2,<0!;<)/-,@=B$>8)2#E>H28:0+">2>*)>561@'H8G+8F"#887.4)#$&?.$@74/*%C.+@C'?<'1C8B#%:)(00)!:>(7B2A-;G+7:.*/.!.@*@;FBD=(:0H&$=+'<+<0+<($:!F,-6C3
@r792
CTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGT
+
GE2%H$A1%1G.+G7<0"7<B$A-+,0F'@,53%@B=5/4*!4A&8)3)48"G(895*2&,,9>
@r793
AGGCGCTGGGCATCAGCGNGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTNT
+
<-H;'2%98<%.&4G3C.9H2@?G@983>@"="26.08G3F(A<:95(F<CG1:H'#<(!0
@r794
AANGACGCATCGNTATTACGGGGTTGGAGGTCAATGCGTTCAGGATGCAGGTGAGTAGCTGCATATGATGTCTGACNCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACNGTACTCAAACATCGGGTTGAGTATTATCTTACTGT
+
#&"+;!1=&:'(2!G:0(/)#B6,.ED:"3*HB;%+>98/6:+,EA*H5%:H.+:4@>CCA$/!1&+&4%DB&'/4'=""$+D,1,-1BG6*C:7@,'"#31:0?!&4,,29@))/#%BGH(#"<1B)(!)D2,1(D?&"2:#!/(;F999=B-5AH2+,C3'4CF;2#@8@;-)E4%B:9):23$8G3$46>G;C-G36G99%7DG5GG4-F&.=:3:,G;F?*564E-
@r795
CAGCCGCGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACGCACGTGCGAACTGT
+
!%$()*&+"'#%'*%*(#'$'&"'%'&+)$$))++'(+"%*&$!"("$%(*&!+&**&$)&"+')'*#)*!"')%"*'%!$
@r796
GGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAG
+
0+H%/D>>%2&)/;&<6'C>'$,B10B)DG)%=3@!?>E?'C/+B((E'+05.#'$D?E97.(&:H:?G2+8-!;G0D;---.&!4,
@r797
GGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAAT
+
=E1/1+/@/E73G6DC57H%&<ED161&)G70E/=!H><@8$#6HE'H1@99%A.8D2!
@r798
AGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCNA
+
>%596'9FC>F!4@EGG,<&64</>70*:>$B.-?H.,=G2<97=
@r799
TAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCNCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCAT
+
8!AH35@.?%)0C!2'@"?.B=#(;C<=>#7A)"20*C:%'1@@6#<$C-.$($1C;2.0568?*<->22;0-A$,34;96EB#?3=$A:5?998;"=3FCA8@A@=C*3&D#31H4/5'*E/CE$&*
@r800
ACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCG
+
16*)@6.3%B89H.:+4$G<(/9>!(8(=>!8/56H4#(?9@G9#A#'%C)?7/H4;;
@r801
NACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTTGTACTGGAGGAGGAGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAANTCCCTGC
+
!?493$"2)88+.7$/:83+E;-03(F(B4!)&E%8"/8)#%,9><6"&;$!7B'F%#A52H*%AB27+->HH5624%*1D?$')GF-4F-;!0D-:=6E6A9=/"F#93;-@+.FFC)>BB2<2,08,9+'!G%GA;)*/%(G
@r802
ACCACTTCATTTCGCATAAATCACCAACTCGTTGCNCGGTAACAACAGCCAGTTCCATTGCAA
+
H8.A686?1+;)-"79,7=:&)HG19>'+6HF70++62,!6&?2>$2-B&-(9A4!?7"0HAH
@r803
GCCTTCATCAGAGAAAGAGACCGCGACTTACCNTGTATCTCGTGCGGAACGCTCGTCTGCTCAGTGNGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCACCGGGCAGGACGCAGTAGACGA
+
0&23G!E8):7?F%>#7$#7!:&%D%'>&+:EF,5C"(DHA6A!/&08/6,$*);*</87250:&4>&@24D)D,"2'/@):?@0H3H+<9F4E5)11@$(C3B/.:48C"$)2G-#==DF,'B$+H+;<:*A.,8(";<A&#8@?CE=;,C6"D6./,G8?8&55C">0'@@66E;2<*D?D9!E)A@:!F(9A0A/!H2!@<E<=//G#D7@4!>D<E90%/@8E*
@r804
NGANCANGGCTATGATACTCGTTNTTAACTCAACAGAAGATGNNTTGAGCATACAGCCCCTCGTT
+
!"&!+&$'$*$+$'*#**)")#'!+"%&'%()!$!*#(+'*#%$+('()!*)*$%$!$%))#)(#
@r805
TCNGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTANATATTGGCCTTGGCTTTAT
+
D?+#-37+<=/9.#;D(>-/D7%%*>8!0@0"%48F#@=,,F)A2))AFE@=$+-7(.,&)&289-6*5G51C$*&>B5C;FD,."@+!B:B0C"55#@)->.*1E50'.HD"&54E<
@r806
NCTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTT
+
">A65/'=>3"",0E-;E,463!*8,3!"EH'E5'-EE;2(D<0.75"3+G6"$BA=.*A'F@)53;#55HH=$5<64"*<A8&
@r807
AGTTTCGTTTAGTGCATTTGATCCTATTNCTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAA
+
'*'$+$'&'$')!+!'(#!")#'+&#'+(!(+#+"&((+*!&!'#*))()#")"#($$!()&+#%'$!%""'$()(%)$%!)%+&)'%%$
@r808
AGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCAGTTTCATCGCGGCACT
+
0G8#A>HC$>2=-*$,1-09)&&C,0-(5C33(F%'&A,!&?)8.(<40;A9FE-?4D"=((H5',:9;78(>&4C)<41G8HA(-9A:/(+"15E(
@r809
CCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGT
+
:"$*2-//#C&DH-/$A.A-012;1"+$:6':@&2B0"*=2$0AA$";,D!="#1
@r810
ACACTGCGCCGGTATCGATATACATTTGGTTGGCAGACTTGAGTGGTTTCACTGCTGGCGTATNACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGT
+
8&G4$6,9@9--0!H3D>/?59<:0-;-8A18/<7&.&8',G5.:5-$+*59H<!>HGB84,=+D+3HC(-'%29&'4%$'8D%,F(4:)'*)%C(*E&1"CE@"/&,7<8
@r811
TGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCAACAGTACCCAATGATCCCATGNAATGACAGAGTTGTTCCGT
+
$591E(.6+%/',G2:=BG6:<?)>:/F+5(A*)6?:?A++5,!?8=!C51>-.0#>453:8!#>5"!*.80:H.0-*F!+A%$
@r812
CTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAANCGCTCTAAAGCTTCAGTTGAAGATATTAAG
+
89.!7DH8>A)C=:D-2F+:@7F&B9/='B5!'5('65#H:4/,9=46!*(G:'"'+(130>60A+-,$2=7;*4#.%@65:,'HD"1/?3?5D"4?4GH::7491AC1"5##5*H,.
@r813
GTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATNGGGTAAATTTGACTCCACGATGGGTTAATTCG
+
/496;A):2)7>4B;-<2E"!(-=G$49&9A5'12BE("6E+%-)@=H;4C=-'/?=B+@%/'9$#(*7:"$::D>7-?C.;)6D+)<+<:$5E;7
@r814
ANANCCNTNTGNTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGC
+
##)"#'&)#'%)+%!!($(%'!*))$%'!$**!(+%"#$&)*)''"(!$&(!)&*&)$()'($#%(%!#)&&%))''(*!)!+!(")!%%$%#'&
@r815
ACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAANTCTTCTTCCAT
+
C"C/EB?,7@69*"C*,:758'+9$2&4E2#'!.&;=$10#99&7G5!'0/;/+G9=-60,,,$74+EA<8;HE,(-)F-CEC!A"C@0)0A6:&-%5,4E:!H?!A$@B2&8(0B/%%AF<H1#!'*>5/BEA3%;"'=%--B35.04)3GA&;"5C>>H,-5!%&D:%#"&9!5E4(40-E':&&E';C.5@(?4(;+'?674D?A(-'?'HE-><)0,<;G?2A(C"<"$/&E6)'G@&65;08
@r816
GCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCANGTTGTGAACTTCTGAAGCGGTGATGAC
+
'3+#A5?"++37G':+*:F4=;"'EE7&4A,)<0538.:(270/95"G.CB>.>?32(?7*72-4%+,)D'=H8"32+DE"=)9::$)B20A6D.('&)-?0.-*&!'32+@G%51C%+
@r817
ATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGA
+
4EA598B'&G5C9"#1*766F#D8/AA+.5""*F4G*/G/&80$@#3-8A)45-GHE)%),/9B%H-)>2(?A1&?"-%9(+>>0>9A+?D"45<-:(#C"D*D"65.11D1!.D
@r818
TCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTG
+
=>>:66&$",5.2%D"9/&AE)02B14>B60B5'E0)4&%;$@$@H*G6>/6&/%<HA5)-A0*%#/,>.6H$H1(!3AH=44(/BH%'738;$<1)F'9.#/A%F+C?%*%66.+(,-4#6%94"+6)C"(;%.$,C:%+D#-C;2/8F8H<H9*?3AE$*4HF*'#-;)00@+F%A,?/A6G=5?%0A2,&)5:<9D+:EDHHE4>%,@1B6!E==3'3&)7=+=0G%!F#ED)"FA9<2G8#58
@r819
NTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGGGATTGCACCAATCATTCCATTCAAAATTGTTGT
+
#>!1B5)6;#F'E8);"#?0?5(8G*%0)(+$-788?*D,#"60C6CE(H;F"?@H2A<%B>F'5>:!4%F!@&D(#
@r820
GNTGCTTCNAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCTTTTGATGTATTGCTG
+
%"$'%+'$!"%$&*)!#$'&&&&%))%&"$+%"**$&'''%"'%)'!!+$"+&""$%)$)"+""%'%%*"()'!'(((!$)%"
@r821
CTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGA
+
()>F;B5<8436>B2#C<+<$2A@1@;&"73/)@B:FH'3G@)#A>G*D*2?/7=')<',.)>?&@3G/+#E"@H'F*+9<"?58$EB)F;G#D("1C9E;3GC>E?<51#9=<3C+D"$A%0,A%?E'<!$08AD"=,?%<4,(B/"C/337F35:/?@7*-3.
@r822
ACCTGCGAAATAGCAGAAGTGAGGCCGCATGNCGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAACTCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGNCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGNCAACGACGT
+
+!%%*&)#&&(%&"'%%*#*"))))*(&%#+)!(#%'(%'$#%%+"*++*($)+*'++!#*#(#*("($'*#%!'&!$"#$&"$!!+*'&'#)')(+&!$$&*)$%!'!$+%$!&'(%#$*%')'&(+%((#!(*#""%%!*$+!!%(%!)&#+$)**)&!&$)+"+*"%&&+"%'#"((
@r823
ATCTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTG
+
<<E&B$+19;$)"A2(?-'H'+@.HH@6$5,%'#::E!#@
@r824
ACGANTGGATTCGACAACTAAAAAGACCTGCTTATCTCGGTGGGC
+
;#"FE%GHH#@?6&EF??5>$!C/+EE>F'#%&A&%@EGB,,C>3
@r825
ACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCNCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATNCGGCGAAACCCGATCTACCCACAAATTTTCCTCACTGATGGTCAGNGTGTCTCCATGCCGCAGCTGCCGCA
+
+((!!))!'&&)&+*%+'%$$$%'')#*&*%'(++*"$&+"*'+'#"$"(%%+")&!#')'$*&"%+*&!%"*&!"$'!$'''$$"++'%)&'*!%("(%'+!$#$&&$"!&!$"%#*$#*!&$*'(+"&%'%&'!!"(%%"$$$()!)!)'&(+"'+&!$+(+%&+%#'*!%"&%((#%$'%*"(%)#++)+$&!'$&$"$'*#"'$%)(!'
@r826
CGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTGTCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGNAAACA
+
GF!<-D/F"9$)0D#$>'6EE.E0!;6,>9BA%8'8FCE?B15)),C2ADF.5.>)'B1'<)0HDA25+9B3"A/,A70'*7F*3?@7@F"H1,<'&1,)!>,!0:5C+(*=,7*'$<-5#9B0BA!8;7'H>2)H6--&E.0C8')B6F?;*@H.G9+'3E*/?H,,+1,CF"E6%-407.)>+*/.)@4."$1929*>(971FFA7/F+>=5((3"4:?G6G#G43!5G?;
@r827
GAATTGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTNCCAGCATAAGCGTCTACATGATACCCACTATCGCCATCGGCATTGCCTCTG
+
)'!'!+$("+!#)"&$(+%'$&!+"'''()%((&&)%"$+$$"$&'(*)!+%&+&)!)&%'#'*+%'!'$$)#"##"(+&+")%'!"(&+%)+*+!&%))&&(+&%$(&&"+''"#')$"#$+%$')&$#!(++)##%)*#+&')$*#"&!!+)'%&*"
@r828
CAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCNGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGGGTGGAGCAAGCGTGACAAGTCCACGTATGCCCCGACCGACGATATCG
+
',D/&)"H!-#D%*8F&G4567<AG%;3*F76?*;-7.23!E>FG362@+EB;A7B$5;3;D=34&/'@=)9D%#9!,$65>1092%*?19;#7C!=2,<*2$1,$.40@38"/G>4&#1+,F.>EB:.12$H9)$,=@)
@r829
TCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACNGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATT
+
=49+H7=%)086?08=*',7&1ED!/+9H"9#H%1D,>8#?)2>;A?6C=;%#F+H1/!4G9@C7"+;(6H@BC)A!!G#*F/G(@$H#B2383=,&4C3(46A@/++=4C2/;6+HE2C)1"2-?+@-/&<<H!,0<F4/:F-41+7:;)#E.>(F:52;%8"H>C?.*>&>H1/96B>9@244H,:/+;"#5)3E:=;-AH;;9E?0!,GF#-4(-;?$F;E"1F=9'E<=03578<C*G,C%AF%5$=.7E<8%/FBE
@r830
CAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAANAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGANTACTGATNGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGA
+
$'$(((+'#%#$!'%*(!!+&%!$"")%!&($&&(")**+&*'')("!"'!"&*&'!(''(!&!+&!('#"'($(**('(%!+#"##'(%)$!&%'))**$'*'""+%'!()'&%**+%)(!*'&&))#!+*!%$"#"!&+#$('*"'!)%(&&#%*+))'!&+')$+$+&*'()'&'(%$
@r831
GNNNAANANACCAATGGACAGANTCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAACGAGGGAAAATCCCCTAAAA
+
%"%%%(#""$"(+!%"*+%#)$%!"'!)()&)#(%%+!#$$!"'"#()!(%%)&%*($('#%('!+(+$&(')!+'$(!)+!(*$$)$"+'###)'!%$*'$$(')+"#&$$+(*")+!&%%'$'#'"(&+)+%&(#++))'#*!!+#&$*"'&*#!*!(+("&(%%&**&%#+&*&"!%*%((%)+!"())&
@r832
TCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCT
+
<-"F&!HE%2%<,/E4"$CF:6)?&+4$A82--H8*"<2(:01*"!BA)A
@r833
CTTCCTCGTGCATCCAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTAAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCANATTCTTTTGGGATTGGCTTGGGTT
+
F7/0H;E7%B?B:3?H9=+*54C#B1D)&+E9&&>7,;-@%F99-&?1.=BA&1B=&?/1H.1<$9.,!H830?-"H<=>%<CC75G!'497'/B->>45B>85)>G/D9#0"D3)9+#:,3'G8)@*053AC5%H$H/!'E7#:0?8F)<A,F/'4F#:-A"2@-(.=%D'/8&A2*<2ACD,&8D1,%%A".(BD@3EF4)&0B25,5.<?:E<?-,-HE(8%9ABH5*5!?42F+;11(2"8:"&5-2"383",
@r834
GCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGA
+
?#$*8,G,ED>DAB08!5E,4?'85E-H4-E+/7*G2398*&HDA
@r835
ATANANNATCNCTNANNNTNGNGCCNTNTTANNCCNCNAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGTGCGGCA
+
)*)!#")'#%%&'"#)!%$")")#('$&%$)!!#*!"$*)'+#'((($"#'+"(*+#*&)$)&&'*($+(+&)&'%$(&)#$&+%*$'(*%$%#$!!#'%!$**($+&%()&((&+'%%$%(&"&*%!*)!)%!"(#(())!%$'"&&&!!"'#%+'!+&$*'(&%(!$)*)()
@r836
CAACAGGCTGCCAGCGTTCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCG
+
?-?:(;8<?):;,-!+8H5"(&::D0'2#9747F#G*F$?E#*6"*%),66B)!086
@r837
TTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTTGCNGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACNCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGNTGACGA
+
48;A*<=826<3?.?8C-==HDH<@D'$:?.3!7#)/=)'3*<<22A#?$.H2B!=5)0%?.1E#C81E?&G9C@B$B=+:!H:2&9E=!H&.@#*,%5&#B,A8<')<D!C485<"@A'54A@,)"BC0D>&&E5+-+%@>%2D"/>-'%4764G&4'1<GG@.&</+??695.=";;B8B3CGB'B=5<A7HG#-;+(+0E)=0?6H;<,,4;*'-;*-3D=+E16D4&AB
@r838
TTTGCCCTGAAACTGGCGCGTGAGATGNGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTT
+
D+BB1&8=-8&'&E!0;@4?>/!1$A6H@;/!9><?&5&3!+F>6<@F(8><2G3>3CG+E.(>D1-E*=89'80,-"?31B*@#)-1590-&*FC'
@r839
NCGGCNNNNGGNTNACCGNCTATANNTCNACNNNCGNNNTGNCCGNNNAANAANNTNGTCCNNNNNNGNGCNNTNNNNCCNNNNTGNAGNGNNTNGNNNNNNNNNCACTANNNNCNNCGNNNNCAGCNNN
+
$#!!#"#!$$""$###""$"!#$#"!$"##!"#"##"$$"$#$$##!#!"""$#$$!$###!""!#"$$$"$"$!!"$""#"!!$""!#"#!$!#!"!"#"!!!"#$#!!$"#!#!!"$!#"!$$"##!#
@r840
GCCGCTGACAGTACGCNTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTG
+
,5(#C>4,78:?;($F)4,:;H9G76:.%/,48H0)B7D2>2<&6;/:26$AD-
@r841
GAACTGGCAGACGNCATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCAT
+
-+<!EB+3'"E+;8-5@.'80G;,859&?B?0)*32CG3!'DB:10+,05=603A!@#@6A&$F&F
@r842
TTTTANTNTTACTGNNAGTGACCTGTTCGTTGCAACAAATTGATAAGCA
+
$)'%$!$$#$&'$)(##(+)&!++'*$()!&!%%$+$(%$!!*"$!"+(
@r843
GNTTNCNCCCGNNGNGTCCAGCACCGGAGTACTGTTCAGCAGCACGCTTCTTAAGCCATCCACCGGACNTTCAATCGGNCCTTCGCTGATGGCATCGATCACACTCAGCAAC
+
(!)%($#)"(!$!'+(("$#"!$('!''+'%!!$+#"#&"+!&%'")#)#!'%#%####*&+*+*$%))+"+"((&$!!$*'*+&'#+(+)*")")'"'&%&*+#'"$#%(!
@r844
TCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCAC
+
H*+?%F-+%)=9H%>42;D"!"=%(!?1D11%*#$*F*<0#49@<<,B.'">0=A>@#3&D:C++;87:;8E"B,-0&F-+6"BH*=0:03!0AD@,1.)0<)DD%4%4"/","<9%7@3#6*&5,-DC9"?
@r845
CAGGCAGCTTTGTTGTTCTGTTTNCCAAGTTCTCTGGCAATCATTGCCGTCG
+
+<!D/5$8&"8++)D>9>*6F2BH6442#'@@;?(8$F?-+9-C0<G&3&D'
@r846
TTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGC
+
;$#F7C<+$9/AF49)7'")!"4>,&79G+'F+<9."A*C"<2/,*@$)<F<33:1."#D
@r847
CTGGGTAATGCGCGGGTTGTCCTTTCGCGCTGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGT
+
<#@$"F7DGB3G.D,5A0FC41("6E,9)*4?!<:BFH98B,A@@18>D>/EA7%/*G%$./CBC)F:1HGC*5!H4&8;:D-'$<-+2&HBB@9#)6*5?,>%B:(9&*8,A.D'7#552<;0*!E*20BG)/F"8H.G+;A!C
@r848
ATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAAATCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTT
+
&-,0+'$35<5-.7:5>/#E:0!*$<(!B9G**=4D@*7%;C9E:6G-:+6;@'4%D#+>2@,*=$1.4/8,?9;-)15!&A*!617)/92>.3(4#EC-;8C&7'..)92,;:#FE;"!!77>FF#F1:9(AC872$D<AD=+;"3%7@21?-'D,"%&?"7)7%7<9!=0>B2:'$0@$>(F:4?2A>9;7,)$=&HG!F&$0/CBC+&.+:>!:-9C/4>'C%.B;
@r849
GCCAAGGATATTATTTTTAATCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAATGATGAGGCCGGAGATATTTTAACAGAACATTAT
+
%5)*+%G942/5'F96E$.C:&%A-8<03(%=*<<)A*;25&49H6B4;04B2/65F2)*F"003-<-C:A)8D,:,G-?C&<4)35F57<GD
@r850
NGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCAGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAA
+
!$'*#GC93,2!0G'5!11#G!13"!"0BA84F+.>H'G)=%F5&'209)7#9*?;83/BFD150:#D6B!:.+5D$,5:@E*B26B:C)$;<9!%*),69=G5/6<$0E@C9B=6E@,>0(=@E*$"/
@r851
NNNNNATNNNNACNAACGNNNGATNCNTNTGAANAACAACNNNCANCNTANNNNGTNCTANGNNANNNNGNNANNNANNTCACATANCCCNTNNTTAA
+
!!"!#$$"!$"##""""!"!#$###$!!"$#$#"$##"$#!"!#!!!$$"!!!"""!#$!#$"$""!""#!!$"$!$!#""#"$""!#!####$#"##
@r852
CCNTCCTNGTTCTCACGGATACTCACGCAGCGGANCAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCCTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGNAGGATGGCAGCGTGATTTCACGGTCGAG
+
)#'&*%$"'!'+$$'**(!!!"#!&#%'$%!(+#&*!!#**!%++$*(+#&**"%$+#'"+&""#+*&!'"++!!'*(%''&%#+&!)%$)$+"**+%"'+*"**$&#++('''*!(*(%+&%*#+)"'($'$$'&)("!%!")$)&*#&'"#&$#+&&#%")+(&$$*$%&*!+&%%'&(**(#&*&##'!%'%%)&&%#''"&"('$$!$*!$)$&+%!++$(()
@r853
CGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGAATGAGCACAAAAAAGAAANCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAANAATGAACTTGGCTTATCCCAGNAATTTGTCCCAGACAAGATGGGGATGGGGCAGTCA
+
+2;1"=&?8H9@2$7+BH,:BC,:7#(CGB<2.7G%@>7#/EG(/HBD'*!)$8B?B(F&98(85F(:(H9H&2=3,.$F:B0G)&8)9/0&=+H;B3(7,@=%&B=236/A05!402)@4)D%;=!H/28$"#5!.45$1H<5F5/C4H;8,!93861E8;"'60')EB@<<*4+8,C
@r854
TNTTNCTCTCTAGTGNTCAGCCTCTCTCTGAGGGNGAAATAATCC
+
)!')!"&%"'()'&"#*+'&!$$$&#*##&#)&+'!("("((+*+
@r855
CGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAAC
+
7/$1-0:+:3H9DE++@6(9!88&/A$7,%:HAH@/1B*(:%05.7)4G5
@r856
TGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTG
+
5%@(9F+4.4*=8&-&&C@H#*/9.&F37H?'H,/3*#:%,;!)#:=6$??#4&CG:$A(G?EA
@r857
CAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCAGCACGGCAAATCACTCTGCACCTGCAGCCGCCGNTCG
+
;+<'38&63)%?F$:,4<928:)A!)>=B.<%CE<@30-&/1G!+?@GA"<3!3#3-84*;A=#3!($#($=FB)
@r858
CAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCNTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGNATTTTGCANACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCANCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATC
+
+=0'!''-H3"6!A"&)1:2B"!+?=FB!6%E9F,=;-&*)(+C)6&>5D7E:=010/?%E8?&BD9+6:6AH@5)+.$?C-)$!F631A$6C8G2CD5(-C5;9:;854A=9&=C&@0>:%)2,&1=*>B6C2<1D=@/AE828?@/&B.79:4A1HG8$::%8(!D%3H>;3>7'6>;2/"23+7#&"2'9HF4EAB#F.90E4-'&+(GCB<E9F=6<-/G+F/:#B'*):00:739</@FHD6)C0#+?$E.<"''&5FC%#&6:=<''58;'@"2$(@58B@"15"#.&>;B3/<$@="B*4E#+'83
@r859
AGATGCAAAACGATAAAGTGCCATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGNTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGT
+
/$@*9;/5;C>$6>''<4:=A6@/*G(?@+4=B,&/@;/7+9,33<&+*7%?&<'G@D;18@=D%;402=!!D#98F:!&)F>-?A7DC,#;B!DA9.C+;-G$C>8;?;..$C.H&H(8.C>*8'D3!0+%
@r860
CATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGAACTCGCAACGCTGGNTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCNCAGGAACTGATCACCACTCTTCGCCTGACG
+
+)(&%+"!%#%("*#*#&"!!*$(&+%(*#'#"#&!+*(%!#'+$(%%*$"($*)++%#("#+%'%%&!+$(*)'*'+'$!!*'%%"#(+#%)$")&'"#$%%*(""'*$)''!*!+"#$)*"&+&%+)+%((&!$#("#!($+&$%#$+&&"$&(%$&$'%!#"!+&+&&&%"*
@r861
CTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTT
+
5B7#.7-98E@*+*C(>'$BF*?B%*%9D:6@7#3/=*/!?.<0H&#%7A-$D<<6)8"D1=;F&E,;/6;?$1=F$:3,7C*12E
@r862
CGGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTT
+
?2?2)46.>>+C*:C-G0&%B'HH%E9F1E&C@G(40H!5!*BB)@DD@A.,5-)4$H+5D:>/?B1CE%'4:78+%4,@G36."1
@r863
NGCTNACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCNCCTCTGTCATCACTGTGCTGNTCTTTATCGACNCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGT
+
!7*$';@:!9+!(>G7.%'$01:537).<(>%#7+&;-E92*=AH6A*:<4)5>EF,,//51@,*%E<:6:$CD!9?*0G4FCD$,!+4C71/."$9,"+0@'/-D.H-C%E%))#=-CD#.EH1-$;+.-.E"'3$(+EH(<&)'/78CG6GEE@>;A09B0!C!D**:ED7A(,8D*A#/#:#C4($$:4"EG5+A)$=%-?<@75'H+,)0/A(D8D-0$*B0!&70-
@r864
AACACGTCGCTGAGGCCGGGTTATTCTTGTTCNCTGGTCAAATTATTTAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCC
+
*%!#%'$+$""(+)+#))"++&!("%'#(+'++!))"+!"%(*&'%(("$%'"%((!%)&"'%)+(&)%%*)&!"$"+'(%))''*(!%+&"%%%("(
@r865
NTAAGTTGAAAATCGGTGATTCTGTCCATTGGTTTATTCCACC
+
,H7$&@$+A(<5+,$'5C',*($B#+08,5.2&&?D"HD*:B6
@r866
GNCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCG
+
-30"120G>+5<8$=#6H5HE4<;B7!.HB%-H.?=0,%52;DD<3&'/.FB<81#B:AGB03!E-G46,#.+=-E//B;3
@r867
AACGTCAAGGCAGCAATCAGGATTGCCATCATGGTTCCTGCATATGATGACAANGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAA
+
",?G<.D2:C6-+<:+DEHF<"%''#GG5DG,!@B',E%B*=20#2D0)<&0F*>=)FH0)2'$D6:FD37-4(5;4!5HGD6.77$D2!
@r868
ACAGCAAAAATACTCAACTTCGGCAGAGGTANCTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCCGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAA
+
)/(0.0"$?&9F7<0.A&08();/E.8!=,G8%&7.2CH".?C3!!*2&9>87EF;A'3!&%5*$(:@#HH<C8>':!/=#'3(0(0#6HB@18.7EA4/#,&4:23D/"<6+'DF9B92?8G(;/*!9%??DF>-H=*4H/E>++)C?='<$*'D:<7?"%8B'+<7<A(<@)F83?A@&=6<4>21.&-87@(=0#(?>38<2&?#9+<E).FE0<)!)9'@2!..(75@=33H<H;,$2<#@>)&1*%
@r869
GNNNTNGGNNNANNGANNNGGNGNACTCNATNGCNNCTNGGTNAACGTTCCGNTNNTCANANT
+
$!!$"#$#"!""""!"#!!$#"##!$$$$"""#!!!""!#$$#!$#$!$$##!$##$$#!"#$
@r870
AGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTA
+
!$*5?69-53&'1H14%0GGGH+A-5G@0$H752!'C6;$<5346
@r871
CCCTGCCTCGATTGCTCTGAATGCTTCCAGAGACANCTTATGTTCTAT
+
?;C&"D'1@<5-<5F5,H)B"B5,=+D?GG<50C)>(*)??E)=2$6-
@r872
CCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGATGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGC
+
45D&5!@:*E7;2:C(*/2">;$)@C*/>/+$F6G(B7&!3B9'#F<5A3B!$&#((A-7>/-9++D45<'G-)@""8-H3'F#)GC#%39$6-'G)#EAEC>;HG,B0=7C9$8#6-=F9C(98>D0D).(;B0&"G74B9).6%19"CB'0(H?31@6*D9(&CF@3.0@>-/>725+&42.4?C79/9014-0)3=%+6
@r873
CCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGANAAAGGTACGCCGG
+
2H</@%!5!<(+)4.F(135A*&)4!/D!4E1419%/<=($21,1<"=E&$4+33D%4::<+D$%,,85H8@F@
@r874
NACGTGTGTTAAATGGTTTGCCAGAATTTTCAGATTTCCACTTTTCA
+
"*2H8+E,"=<AA&',B<#%E-2:9/D6/!.!5G4B&C(-5C(FB'$
@r875
CAGCNTTACCGTTTCGCGGTGNTTCTTCAGTACGCTACGGCAAATGTCATCG
+
H$29$A(@&8!@4&7<)B&4':%*%?@5?8B1CF2/*'+G4H=3&37C?*'B
@r876
CNCAAGCAAAAAANATGTAAAATCGGTAGCAACNGGAAATCATTCAACACCCGCACTATCGGAAGNTCACCAGCCAGCCGCAGNACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAAC
+
%(%(+%%$"'$+$)!"&'#)!!)&&)#"!)&+"#!*!(&"%#$%#(&'$&+*'$%#*#%$"(!'"&+#'!+++"#'!*$$)*&")#")"&&*+&+&$(+('('!'&*!#"+*&+'*)#*&#&!'"!'#+$#+"%(*
@r877
NTCCCTGCCCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAANCACCTCATTNCCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCNGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAG
+
*%*$%#+##'#!''&+*$)"&*$!"')+#*$!*#+#'+*&!#('$'++'""$%%%&+*%+&""&#"+&(*"+'""'(%)!)'#*#"%(("#&&")#$%&(!)'"'&$+&)%)+"&'(&#*$$""'+()"('+%$)*!**)+#)'('*(+!+$&)'+*))*#'"'(#))(!)"%%(%$&"+&*$*!!%"+*#("$"*$(%&"!+)#$*&)#(&+#!+"*(*#
@r878
GGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATNCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTA
+
F"!<'!517>EF/%F.'55B,*,D=D#:?$;3#<(B.<;>6-$1$-@$(7E3&'")@1-5+F!>2C@(A.!+'5D::D>H"3F;5:E96F)21;+0;G?F#,4*6'#9EC/F><7)C3*E3E7F5)271EB7C4830:''>/AA9E/&5<HG<85BC&H9--#.95-*>3/E!!)!C8(2G>0"&0%:9;H#H
@r879
TNANGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGNCGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGNGCCNCCTCACAGTTGAGGATCCCCATAATGCGGCTGTNTTCTGCCGCAACCGCTG
+
)#)!)$*#&*+!(&#*'!+()*$*)$+$*++)"(!"'&+%#!&&+%$*&*"%'*")'!!*'+$+"()*$%'$&""$)&!&%!)($"!%&)')#+''#+&!)!%*&($&&##)$$$!$#!&**%"(%&$%#!$())%*'+'&+*'%##(#%))('*$!$$!'*+)#&$*+**+&$)''#""#$!+'$+#%&*)%'*%"!%"%$&*&'&!$&"&!)!()%)$("%')'(++$$*!'+%%
@r880
GGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACC
+
/@9F47<1%,=/.D8->C)7='>4<E4<4GA?A&'#>C2'5;!G0:;9$'-(48F:9G,;'=>+')@F?$%?
@r881
CGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAATAATCACCTTNCGCTAATGCTCTGTTACAGGTCACTAA
+
5<E6C17,14,H8HH3.+C';.D#8B17=G0#BF>78<E=/##C)2&&5<B&-;7=46>%E;3/G9%',+35=>0CA
@r882
GGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTC
+
9"H):>3>3'EH6*&$1=CH&&9/:D$GD0*;,>%9F7('(
@r883
TCCTNACCAGGCGTCTTCGTTCAACTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCNGTGTTGCGCTGGTAAT
+
#'%$$*+(!#*+#*!$$(*)(%!)"%'"#)(!%&'('&%%)(!%&!#)$"&(()+&'%%'$%((('#!#'($$)*''*#*$"*&!$$$'#&"***(*!+!'*$*(#'*!(!%$(
@r884
GAGTATCTGCATATGATGTCTGACGCTGGCATTNGCATCAAAGGAGAGTGAGATCGGTTTTGTAAACGAT
+
,;)AC)#"8+)!%?7:+1/'H1?=,DF&$&$>!C@C.!2<G?)B)!,"3#!/1335#5+>96-@D=GF''
@r885
GAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAANTATTAATCTG
+
1?B#F!@..3G@HE5&:#=A*D,DGA5=#70H'.FG*0D;#:F!:,.)(8(:,
@r886
CGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTT
+
,!+:66AH(1(8G;/B-=D*/<;%(./6A"()@.(%D)6E$1BE,)H$<>G:.#<=@<3*/?./7<>
@r887
TCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCA
+
9:E@"=-55!"3/8A$)2(127.#G=F$)G94C"4<3H"'
@r888
GCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTNCAGAAANACGGACGAAGGGTGGAGTTTA
+
$+%"$"))"(""$#'#**)$*"+$())"$$(%"%''&*#(')'"%+'*%)")$)*!$*)'$%!!&+
@r889
AGAACACCAAGCCGCCTGATGGCGGTTTTTTCGTGCGTGTAATTGCGGAGANTTTGCGATGTACTTGACACTTCAGGAGTTGAACGGACGCCAGCGACGTCCAAGAANCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGNTCAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAACGGATATTAC
+
D?B0)((H-6<4FC:-@@9+H122-2@'E4?;@$/D@B/?%<CH7<0D$0(AC=1>%/GD:7>)A9;2<H&:)-00?8#!3=?'B53#A@&'<67/34B.)16&<E%>6F06-1(&9C"5F/&?D*H:!<-16$)#*/C*B<C&>9@.7:$1"+:$6D6D<1B;4CA=-%,;24E1$#-597!*'8,64<8.*)'G%B4=/"=A+)":.(=2'!848E"&/A",:F<#9B3FB5:6:$,=<338;/9?6#4-/824*8:G#8=F'-6)$7CGB7)#)(2=+)=E>$:-H(/8:+B95=.5E/'#?(*&=G95H(C'+#C9%.$6/1
@r890
AGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGTAATGAAGTGGTCTGATATCGTAGATGGATAT
+
9,GBG*:6'!;*AD//:,4AC8+"F8*26?H7<+F$)BH9/!9!2?5=="@!4**$3$/!1&32F068#<6%F8D'*(%(:G+;+:>
@r891
TAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGNCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGNCTCAAGCAGCATATTTGATANTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCC
+
1.04>FF"C-#,@A?1-.*5),'2)#07!.-:5)C?-85G%H:E0G=)*08=+'&08?"!&%3)E,(=":!;#%=,9:0.9BBBG*D#()(%9BD:%952#'"$#E)E!G)+.+55,23/@-."3H)0(C<9'F*?0!,4+F:&<97D)";B'8.*;1-=B52<>>4A%6":-C/2H62=.:%C.+C=,4
@r892
NGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAANTGCTTACCACCTGGCCCACGGAGGCAATTTCNCATGCTGAAAACGTGGTTTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGNATAATGCCCCTGAACA
+
'@>4%F0(@?:6";7@F'%&C9<(55AF2$05+C;201".4+%885=FG-A?.*>*,-!(6<9A(4;:,+?:2<$#E5,=7??6<HHF.>0<H=7*=A:1;91.4+'8F?052.#D?50B3=$D1#="(BC$.F>"5&A.%31<4A7-1="&-G)9AE(8=?*:C4>/=/H6#3/E6F*=G343<4.
@r893
GCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAAT
+
F9CDA68"5-F>0HC;(1B'H!!F.%>B9FC*?.A*%.7A$?(?8(7F(320/C,
@r894
AAAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGNCCCTGTGGCAT
+
%"*+%'**('(+##!$%$+%)*%*'*++$"*$#!!!'%&$#+$$&"")'*(!&!**''&"'!+'&(#)&*(#%$+%'&&!*$#+%&")'#'$')
@r895
GTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGTGATTTCCGTCGGGCAGTATA
+
A%!7C43A?5&28$HDH$5&59@=0:4A!%+6.?*+,#*3E2!>3GD1G9//.>9BFG+?6)6C)B7HGA
@r896
TGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGNAATAAGAATTACCGA
+
&HD3B+,D?$93?7=??:6&E&$/$1E$+:?G'/4(0B06=25BFH%EH&/;?=?"3@*5
@r897
CTNNTCACATNCTAGGGNTTGAGATGCCGGACTTTCATCGTNAGNACGACTGGTGGCGTAACGGACAGAATCTCTA
+
*##"&$&!&$$$"!)'$!'+*"(('&!&%$*%)*%')*%#*#""!!%)')!+$$**%)%"(%"+++!)#+#"!(#)
@r898
CTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAG
+
'$++*!!"((&##**"&$"%$!!+##+&&$%'(%)&$#($'"&''$#&*('%
@r899
TCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTNTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTNAGCCACCTGAC
+
&EAG5E:%$G,=)D0D(40D<C@E!>06=>1?8F91D%75&?*:9;*-3'@:A:(2'CH@##9$%C=5418>,%FC&<)G!52340F4<!2?79;FE#=+0');1)60EH=D,G9ED?#3+98A2D-9>$9F#B2C?/?72D#'9;5/"'!D6!()@*7$'+/5F7;C5&$?=!&='3@G-*!%BH#"3)(/-<)=-4"%:#B1!F4441B-FF,2670;F%9/,A/&,".2H%A6=(6B*.B:40&7;32-)!,+'=,D$$748A6>>@!1-G:;)'>./CCA@;<3@=4/-C$.+"+6",;E0%0C/."%65/3@F6GD7H9<D-(55;15-'3F0"50H*0)23
@r900
CTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCGGCCAGTGATTAACGTTTCCACGC
+
8G=&/C/5$,&$#C>)G+%>3B-$B37(BD++H./(:=A@D>AH9@@>02#4<4/0-)'H.6>+-+CF'D./)6FE-2@@><1+C1!$3,+DE@<1',D?9
@r901
ATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTAT
+
H,=H98&(4,6G/A#:(:57HG$8A+E94@G%GB?A3E*9-'!#0DG#A1,8+41,>%3A
@r902
GCACAGCGCATCGCCGAGCAGAAATCGCTGAGCACAGCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCAC
+
E'B3"H/4'E@-F))380?4)475;30%56)A$!/*#(,3!=<8AE)+4'"<6EC<D)!(:1D4"!'<4F1%97;0C:2%FE%@#93='<B5+?.6<7?C'<FA77D?)+'0$72H1C$2B;=?%2B2.;!4)D6,/G:!@->H,'+=9H'A-G3>%&&'0F&+,@!!1EC?G:#D':.311,25?8&B(G&'E)5A5H;,F-F!DF#3'(>1?=3($"
@r903
ATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGC
+
&<6D4$!"4!D1,7*7+E!10'?35G),0,=8/C7(&1:7$&0)A;G
@r904
GGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGNTTTAAGAAGGTTATGTTTAAAACNATC
+
!72<"9/(1D'9E4<;/,/&C.E$>)-3!?"%3('7@<@A6$8-47G-?#<.'):?%>E<+!HE=H%A0D
@r905
CGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTNCCATGTCGGCAAGCATAAGCGCACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTNTCATCTGCT
+
*$'+)&+'$*)&+#+()!&&("%)&)"'$"$$"*$**+($"#'""*""#$+$##&+'""($%+#$($*"$*#")$))#!**%%+!#!%*!)*%$"#'&))%"#!)#'&'"%+#%+*#"&+#'()&$&"$&
@r906
GCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGNCACCGCCTTACCGATACTGCTGAGCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCG
+
:EG$-.590&!)+"D/98'47A!<,,8@H!BG5:<=.&(+,;"F@$3)?7=,7(.@+F%;E150#>*+')1-D&2D4;FE%;8H$<34D<<FEAG*3)F%A4F11=*:.4;/5*'*'4:5%>H'*D+8&*9-:'4*D/64)C3H+,ABF>="
@r907
CNCGGTGGTTCTCGTGTACCCCTACAGCNAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGAATATGATCGTTATCTGGNTTGGACTTCTGCTTTTAAGCCCNGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTACTCATGTGTGGCCTTTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCATCTATTGCCAGCGCCAGATANAAGCGATTTAAGCTAAGAAAACGCANTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAAT
+
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
@r908
ACAGCGGCGGCGGGGAGTGCGTCAACNGCATCCACGAAGGCGAC
+
<DC<=5B!5%&56$:.;28'!3!EE2F#-#$):3#+8*'BA<!0
@r909
CTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAG
+
-5F;3F=++?"?/A1C2.G&7%7$84*G98"AA=@2//<+%
@r910
GTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGNATCATTGGGATTCCCATCTTTTTTGTTTGTTNAAGGCGACACCATTGGTNTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCTAAGACGAGGTTAT
+
E)B3@$GC<.B+/F:!F@/7DE39%7GDD5C1%;&07FEH0=2F,5C8>FF;,1E@-F69?=.,'/'5.FFE+<*"<&9?E./+1)>=:?;;#D,(GHGEA24C>HCH@&*'5DF(535?>B)$+A6!/1=+"750H*654-";HF@'G$6/>D8A14$C?!@!5.2-H5C2(>$1$;=(1:/$,C6H=1B-"'$)#**'19-A99:/,!:"A;H5$&%<2:8.#D+=::(4H*,"9?FB-F()>3CG
@r911
TGCTCAGATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAA
+
<"!8-B'10H69.-2=@?G4:4;17&?>::C(F5E$C'.7B$G+0/;-9D%)CC?H@C"9H13'"?/4*05H'#?-)08;-9"#;@;/<
@r912
ACACGGCTCTGTATTAAATGGTGTATGAATCATGCAGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGANCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAG
+
FA:'3)?C5,<4'0?'GC.*G2?A1$698G>*+("ED059:&-F+445&E&7:?)$+D0F>;%5/=?*@40!(CA:=>G829%:.(/)+''#F*=+&(%$)?G(EB9:,&%%5G#/>D=."F*;+"!$/$F+3A:"29%>0":C..135$:,3,=:6H3E>C"9?:G/:??%FE('?@(!$B0#)=49G:13%B+*5G<*!'$"D--*F);?08&<D>7@>.'##%3E77<C'?5?(*;G%<8,&?(@&81,720A%'-,6A?A#90>6/@%-=A&E"(B$'=F?28@F*=>H'):;;3B4!.'.>55B95('(E9,%ED/9)84".C!3@#)E>==2G'"+=-F/-C?<'208#"A6B3!CH%D22%H-F9=.&*7E!&C@"9E-!=B2B83<#94#3#!%,CG41(F()2#B4<12%:6&HBD%1!-#:+,
@r913
TCAGATTTCCACTTTTCATTTATTAGAAAAAGTGCTCCCGGATTCAGTGATTTNACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAAC
+
:4DG9A@+BGC46-B%89>9*)9B.-'@D/-6;&&#%:AGE!@2CHD6%#A=%$',%(?8:G.)@+/=?/3C';3=G"@118.)D%)/F.?2%!"7+H@
@r914
GCGNAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGA
+
G)GC@8>-5*+6C+5%:6H'54+7A3%/D;(!?3()5HCC)!9(?"%+0+(3
@r915
CGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAANTTACATG
+
2FC)$82>#@F#G%AFD@AA>F9=/-7DF)EE$:*F7/7EA3:1.+3@?,554F%BA,BH
@r916
CGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGC
+
-/##%"7*&89,C"9;HHA<-"2C7(2HEA=!0#?!9#DB%%7
@r917
GATACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGNGGTCCGGCAGTACAATGGAT
+
3*&%7844?H><<"H(75B,F9;9G%5<H6E!1B&0.<"--F(A+F(H)BF36>"'E'B!'G8='0&"FG$+$7CD=6%$/2@*09..8A<,D7@=.AF5C0%99@'A&<56">G,$"<D<??C7+9:G35CB&<D5
@r918
NNNACANATACANGCTTNCCNGTGNTGNNNNNNTNNGNTNCNGNCCNCNATNTTNAGAAANTAGNTTAATGANATNNTAANATNCCTGGGATCNCNTAGCNCNAANNTATCNNANGGNNTNANNCNANNNCNCAGCNNNNCCGANNAANCNCNN
+
$$!#!$$!"$"$""!!#!$$$"###$"##$##!$$!#""!"$"$$$!#!#!"$!##$$!""#"!#!"!$!###!###!"!!#""$""!!#"###"""!!$""$$!"!"#!$!"$"$##""!#!#!!$!!!"#$"#$"#""$""#$!#$#$"##!
@r919
TTCCCGGCATTCATCGNTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGC
+
<@B!"?&:2;-BH*9:C>'3'B"2#4H7+8C.710#E=$",C.;EDECB<F8*1?GDC2+.E>"824H.*BH
@r920
GCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCA
+
4G,-,A4(?9*C<'!H6D4<G+*)(=DF=</&A=476&=.(;.,,*-BD-"71-3!A
@r921
GGAACAGAATCATGCCTGGTATTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCNTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGG
+
2/'51(C<-0<5<$28D@$(,8):+5+%!D#AH@4#E4#:&*3#-;9.#6H0C3F!$F<"E*,95#"25G#3@9/=6@("#9)303)22D+1.4>A:H"=0FHG:?F@906;7=?0FCE%382(@(
@r922
TGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGC
+
&05CH+=8/">9$;F.@757G0BAE("H%:",B4*-2!/B1,0'BF+C744(/=+2+6F.<"(!<D$403HF2F*:>'!*+
@r923
TTTTTGNAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGNTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCCCTGA
+
*(G&@417*2"(6F0C&$0,F6@6<*&B8D2H2!006E?/B2)DD03"*($@BHC?5HD$8.@E;.F$9%(@%-?>$>C2BHF;!%5-7A:9!H-?6).;C6B,7G@78>C*12/(GC>GE>@!>;@!+"-8=<:;C)"
@r924
CAGTCTGCTGTTGATATTTCTANAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTG
+
#+$(!!)(+&++)'+%'**!#&*&)!'$(""))**)"#*((*&("$**++((#$+"'%!)'&#(%&(!*"*$'"(%+
@r925
ATTCCCCGCTGTCTGCAGTGACTTCTTCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACC
+
8*8*D1&;)B3*?><CB*,<0@.6,"!B=F,8*?"/;@C;'(!<5-,B$2G>)H>*,?*,)
@r926
TTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCT
+
7/A'/@4?&#4DD.50=G;"698E/!<96145&6*:0E'"&)(?2@5@+<*D9H5;,"A5/'B4&@@>%-77A,94$!6E07!,HD3-7
@r927
GTATTTTGCGGAAAATGANGACGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCT
+
G?HA:$;C93$28'8&*".9*8!B;/E!=6-H,3B9-1F;-7C,!&3D&$8="8:@E3G/4"!
@r928
GAGAAAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTG
+
4A9+FG6--$6#A/613(,65@51)#:+8>%FCH>,5E46.7@AC&8!<HG>D:F'/2-=BH3E4B"#58'D9'1E6E3D?2>&"/>@8=E+&76HH1"&:'B/-9E9=C,>G?#/'"11!FA+./2??A<G48&G/,/$!G%3D#;>3*-6@@5C+(0GD%&D=/H)!='>@+-:.%&9-+==#+."H&&A=7"D23B0:6&-#'AD$=!::362%C<E%>65*B6
@r929
CGCGCAGGAGATGCTAATTAAGGCAGAGGCTGCGTATAAGNAAGCA
+
4?-9G5:B$G1=FCG/?A-H)7-5-9!*>A6111E+174)3B?;B1
@r930
NNGCCAGCAGGCAGAGTCTCATGTAACTGCGCCCTTAACCCGGACGTGCTGACGTCCCG
+
$!&)$%##('+**"'"#"'"!"*(#*)%)!*$&($*'#'&(('++("+*)'#$###++!
@r931
TGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACA
+
#G3$#5/',=3'(1:#=DE-G,<CG<>@=BH858;)&5$?/@F-(D:"'$9@!(#$F$";EBD3@5>E/=$-A14?+:23/!5A(->9<F8$!F/!>&")=991
@r932
ATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCC
+
88".!2!CH$%8D*947%44,GB:G,E-E#!/#3%;8HH":B:)BA9"7%'>#))$CD?3:)!?#)%"G02BE@6>8+,6'F",5/A5,0,G"H/E0DD2GD5<?*3:6!,%#9F2.5-+D8
@r933
AACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTC
+
:,'8!E6%2/)E=G)+6)7:&7GA;)5&G;G/@C=C!&AG%?0,<:!H7<<@$+
@r934
GGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCT
+
.6"A.3,3>1<!&'9F-#.+(0;713.5F!36)?"+28B$5G4H;188<,/GD"/G4+;(F.E($(01"G30=7A9,:@==?%)(A&HA26G:$538*,$$*.0EGGF;$<*%64).C-E=GB7H86F57=17B.@3/H5!GC!?;#-%BCG!8&E386@7-.<G9@*%;HG-83&=1H2
@r935
CNCGCCGACCAGAACACCTTGCCGATCAGCCAATCGCCTNTNCAGGCCACTGACTAGCGATAATTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTAC
+
!!+"&&')(&(**"%+%#')(**%$#!**$*#"'''!!)"!#&)&&!((!%+"##'!&'&#&)(++!"!)")+(%(%)+""')!$'*#"$("*#+$!)%+*%&'&(&$()+'
@r936
AGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATC
+
E2GG#G;3;B.,5BD:8/H;B,<)'?#6!':1E#EE9<'10?FFD&B*%78G>1'>=-;>E1(/H:0@#%(<"")7-.:4F?#->AG()H<>;7*$-
@r937
TCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAA
+
/!=9/?.4D(.D=2=258(6H&@.(;CD=+$CD3-$7+;3>&9:6*EA@DCE
@r938
CNAGGCGGAATCGGTAGTAAGCGCCGNCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGNTAATATGCCATNCGTGGCAATCATGCTGCAAACGTGTGACCNCATTCAAAATGTTGTNTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCT
+
"+'!++#*)+%$+#&%*#%&&&$'(&**+*#"%%!(*&!(!'+%&(#*#)*&$)%"!$"!%$&%*&))""'$%'!((&$$+%!&"(!+%*&$"&)''%&()%#'!&$!((!'!(**+*$+!!(*$*)%#)#&)+*$#)#&+)++%)"##!#')#""&'$&")&&')(&'(&+$*&%'!)&%%!#!(#)+&++%)$'(#*!$+)*$#"""))$+$'#"!&%)%%"$(#+$**(#&%&!#$&*($+(&)#'+*&("$$'&%"('"%)"'!')()*)'&&(*+)+!!+**+#($##&&+"'
@r939
CAACAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGC
+
9A1-E"A9H@6CH*<42C,H+'<??EG*9ECC!72'.2GB*,.@)1$'+(9B2&8<64=914+%806.?@H+*,8@'/EG%
@r940
TTTCACCTGCGATCCGCGACAGCACNAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTC
+
@A27",;7:4;,032'C.D>>5;9>06#90<-%)A5.F?9-HEC-8F10:":%9+"%'=,)D#12D(?$$-E59+3*
@r941
ATGNGCTGCTNANTGTTGACAGCCCACATGGCATTCCACTTACCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTNCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGC
+
#*'$'"')'#%%"&!$$(+&(%"'*+!*%$+&$"!!"!())#(%!'&))#$("!*+)'&'"'*)+$!%"&)*"+)!(%&$!##$#%%(*#)'"*%&)*"#($"#+$')"*)&#()$+%$(+#%#&*'&"!*&")!!&!$!%#)"("&+$!+'(!"+("&*"))&'#(()#"$#*'*#((%*+)"$'%+)#*#$)
@r942
TCCCACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAANGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTTGTC
+
0*)8H$C,<7)=*E4,($-B6#6!<!FH%!="5F$&G#<6;C-=+>.D;A?+89@(C++E7;08+)=!4<)9"E'D4)+=0A>,AH;<*1%5&=="%"
@r943
GAAGAANTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGTCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCANCCAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGANGAGGCCACGGTACTGGAGTCGTT
+
(''+#'*$%"!&'!)$)#+))$)#"'%()&%''())"'""'$")&$+$#)#!)$*#*$#($+"%(&'%%)!&(&!)+$(%()%'!!)*%#+(*&)(**+)+)$%!)$#)%(+'))#'&!)'!""!))!$$&$$'!'*#&"'"'%#($&+"(%'!&'%($#&%)$!"+)+"($*"+"+(&(
@r944
AGGCGATCTCCGCTTAGAATTCATTTCAGCATTTNTTGGTTGTATGAGAGTAGATAGANAAAGACAACTCTGCTTGAAGCTATC
+
DCE6#E"4::3E81D(=C%8'$CC@1?/1*!(G@ED<,'G,!'0-#'0G23HE17#4;7B&%-6G.6:"AB;GC2->)22#86"
@r945
ACGACCGGAGCCTATCCAGTCGCNGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACAACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGCTGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATAAGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGT
+
8/F-F""6472?>;(%"8D&+9!$?4B17%&$C6A7#D/2F?AF//3%0:=9/0!()$<94#F.!5""5))"<&$?"//-#??7#%D9B>G*10<40F#>A1B)2:&#;42(G73#";2>A=3B;9)%:G=5%.6G#D$.E<<A$(!2G#(4%F+)G35?$9;;!$D@)=(!<G5&;:<$<(5<(B.;<%0'4<'2D%>%-=9)0<$CC?=0'#9(?0D@3;"4F9HD8+3)$9'04#"@#@GH?&C6#,-:@6G*5H@4;!49ABE0G?G=E1718*H*&5D31CG#!#:
@r946
GTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTNTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGNAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGC
+
*9%-5@>#0;.C<C*A@#F:(47GG5$(B:F;,?H*F$%@1>$.A1G3$@7=?0"51D48<G+BG27@#F<FGF&?*C+/)!:CB,9"2;)B,&51>E;-'CGF5F?*A'=#H.%62>(-HD:9F(!:1(>."$/=-%7A$@<G?",5&+D("643"71+-,"#*6;3C:'&-H&2C@D=0!1"?<!$.89)-8D@*-8)2B5*,.6+?=)3+E0((F1;>-C*D>8>)4E%7'FA&H75=*:(F1@4!)<,E.!E"9?HC)64@3:?F(=E2/*2-F5@#4?92%H;+B-B71,?,<F&1;#3):B@4"@<=D+28/3"05=$A67%E*%0'$;>D4E>;CEDEF'2BG6!2,DCF">DB3:F'.H(10/23>;%2H+$D>A=273-!F/DAB5)H*2-.+>:DD+71A>77C6C(3=F*#
@r947
CCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCANAAAATGTTGTTA
+
/'(+9)'>E&<=4(A6)/,$:9F9H51H9)87;77$E1*<%A$.0'C79CF:D.F)'GD1,$6"64*70;@.!?85!?%#"FE/
@r948
TCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAA
+
H(3(21@#4184?3,=7H"/324E=,6,5#<8#5:)8&,1HG@C4H8")>A$C/1'%B?'86-"=$7F%<$2-!=%<:3#'6@*=)+%);=F&C(9=0>(8,$E<1*(+43!:
@r949
ACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTAC
+
7;%H5&$%/(1-7-"DG%+3+=>3"C1=8A(*.C.094#+%;8*D3&>.BD$$#
@r950
AGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTCTAAA
+
&H1G2$%&,C(A.0G-'/1<-!!B<80:!1'7-=@F:@>+<H/E7$7#2+F&A8'"B71!%:15D(/F,9#,,#);AB<2!C(5*G=+>#2209?H(9$2B%(6':56;;%)?:7H)++
@r951
NCNATNNTNTTNCAGTCNACTNCNNCNNGNNGNCNNGCANCTACACATANNTNNNNCCNNANCTNTTNGTTTGCTTNGNNGNANNTNTNNANCGCGCTNGTCNNNCNAGNNNCNANAGTANNNNNAANGGTGCCCAGNNGANTNNTNANCNATGTANNNNNTCNNNNNCCAAANACNNCGGCCNGCNACNTGGANNCANTNCTGGNNNNNNNTAGTNNAACNTTNNANNTGNNGGAGNNNNNNGAGGGNNNCNNNANCTNTCNNNNNGANNANNNNNNACNTNGAGGTNNNGNTATTGANNNCGGANNNNNNGTNACNNATCATTCCGCTNGNTTTCNNATAANTNTNNNGCGNANCN
+
!"!#"!!""##"$$##"!#"""$!"!#!!$!!!""!!$$!""##$#$"!!!#!!!"$"##$#"$#!"$!#"""#!"!$#"#$"$#"#"!$##!"$#!"!$$#"!#$#"#$#"""$!$"$!$!$#!#!!#$$##""$!!$"$!$$"##"!$!$!#"$#$""$$"$$!!"###"$!"!$!#$$"$!!!!#!!$!#!"!!$$###$$$"#""$!$"#!!$!""!$$!"!$$!##"!$!!"!!!##"$$$""##!$#$!#"!$$"#!$!#!!!#"#$!"$"""#!#"$$"!$!""$"!$$!###""$$#$$!#"!#!"!$"$!$$"#!$$##"$#$"!"$"#!!!"""$$$!"!!#"$"!$"
@r952
AGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCNTAAAGTTCTCGGCATCACCATCCGTCGGCAANCAGATAAGGGTGTTCCGCTGCTTATGCTCTATAAAGTAGNC
+
A"$C*5+@/96/17=,"+<B/+=2.<AB*B&>0B0"FE4=G+*/#2A'D';.H$(:>)&4E-6,2;'FH"!529,HF2=8F?%;#3+D667&#0F=9H?=9&)+/E%)8=+(35=5<0=9=$"<#'6(A@:78%=-#2'2:91-DBF/-?G&=8?!6/@(&"!F&6?G,!F=#@9:D<9,2*H+79#HD@71)(0("/'/;+=+&2?E.5H!+"/+BF@@-?E<D#-'/
@r953
TTTTTTGGTTGTGCTTACCCATCACTCCNCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTATACATCTCGTAGATTTCTCTGGCGATT
+
B)=41?G"D32%"8)$1%4/<D")F3&&2A),%/F%E.8+.,1<>80/@"FD3,CGH;(@'"F2<G&<<>1B4BD;.5A9#(E>>%H"#HG!5:DA39+CEGE"?(!!8?AGHB32:F18D!:*!)E-=G;04""2"'*+"8!0;-;H.=GA9)EC>=#<:#(520D:
@r954
GGGNAGATTNACANGTNGNGGCAGATTGTCCATNNTGTGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGANTGGGGGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCA
+
&)#!**!&(&&&#')(&"#*%'*''&&$&$)"('%"%'+&*+!'+(%*+&((&($(&++"*($!#&(&#*$&&())#(#+#+++%)&&#++!%()(!%!&%$%&+$$'#&"'++&%*!*&+$&!"+)#*'$)*+')(##)(&*)&#!$$$%'&%(+#&'"&*"%'"!)'("$*$)"(#$$!
@r955
TAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCG
+
)8-F<34G1A,)<87E=/7=A&11:<72;H!8926$712D7!
@r956
AATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCA
+
>)3+;E%,+<5=?&4.88>H./C35#4@A8CCC))>+H,:010</<8$4625%8><7#7!5@2,/>%2=1H*+9!E10@8;>%D(&B.8@GA+3"6;46<@EE@)2-EF=$+))5>-G61>>&
@r957
CTCACCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCG
+
!+4!"5E<4!+,8E"7?*GC/7H%A**2"*$H.=81A!3#"82*+E"78C54*40&@/A?>7<,7H1,D9,!4.#(<,@.+C?H6E,1A0CG'.<A6GA5->$$?4A%?"<?8HH'.@2AA2<+
@r958
TTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTANTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTT
+
BHH++EC?+!(;D=<$==C87>@88?+2.35&6/H>:?"G->@.#+4!'641@%:!>FB2&7<"8/A$=4,<@-#)A+>D
@r959
CAAAGCCTGGAATCAGATATCTTGGTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATNTGCAAATACCGGAACATCTCGGTAACTGCATATTCAGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGGGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTAACGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGNACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTNTCGGTG
+
:693%8-$&(H<-+7D?:7ED5)479."'E=>0@G<C>D>89)GBG0H;>=.<G0G!?8>:")7:5"'@--GA:)3:A3H8=*E,<<+;:E$#5H*7<818'#*0#BCEHHB7-AD#""6.!=*"*15H>5%/7FH=*#*CC*7":.416#78?"7H'!"%28DH=!*HBF3A=10CF%5/,@'):CB#D7ED&)4@HG>.E$#-$23/'@72>B">*F9$/5#:453$;1?F;/48#>6=#-?E"F%@$-H11-#<)7F!3@C30H&,#<1:@A,50/'.)-/;0#4$4CH.7(E<'E5-='$4'7,*+.HG6&@?G'G&5C,22@&#@1'F)@D1667D<2EEA"$28'4-1D$-)%7A+(B'=')F$1G1!&B&7H;,2=8B3$9=<!0<::5))E'AEDG(#":(+"+)H8D9>6A3"6C153312="'8;4+A9D$A%%
@r960
NAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGA
+
!/)=1B3B$?,"(+1.64GA'1=.ED'6G"82C8C&1"?F'"H=&%:926/81E"<>%*)#.%)?!+0<
@r961
TCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGNGTCGCTGCAGCATTCGTTTCTGACGTTTTCGC
+
"5-!"!A!/+G-F.A$94>88"C2?!F5:)@C$)""0A#-4BA9"C'-G;>;$-+<C2@D89(#@?C)F2#C'+5027+79(,$8"1BE,D$E!'+EH'!D3$!,,?>*)<<.E+0)509?H%EA@)'=0"B"'#1H#/"2G?2*
@r962
AGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAA
+
+++$#&%'$*%)*%#%$**!+(#%#*'&)*!+#!&!)'&&%#"""&$
@r963
TCGTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGG
+
##!'$*+(#&$'*%#'*(+%&$*""!*(+&+*'&!!+)'+$+&#$!$"+""'!#'*+)+%**)#*!#"")##")'+"**$"!'$&##'!(%&+#%&&)*"!*!$*'!"$+(&+#!##%"+$%)$"))$+!+*#()%!#!')(!$*''(#!"+""'("*)&)'!$($))(*!+%%%++&''$#(#+'%%#*+"#+*+$(')"'(*)!%)'!$***!"()%"+())
@r964
NATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTNTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTG
+
)27D.H>;).0&.B+;#.4*>.*++065+$?F$5+%3+%7%8%*7-&;#-7@F"@6#-"0BE4E=E"A@=E90D*C4-0<%!(<=@@D)DA)(A2<5$;!1;1<>08':4'B59.='/.D9"9@#
@r965
CAGCNNCTACTGAAAGACTTCTCTCCGAAAAGTCAGGACG
+
(&''!&#%"%&+%+&+(#($$)"*$"!!#(#)%)'*$+%(
@r966
AACATGACCTGTTGGCCGNCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGAT
+
=/D<C6'>E6E(A116#G6EC7&1;37G;1'3,&A!'>18(<9?(?7<9G/E(G*$AH<41E0#E65)>#')-)=<(:&&)&+C0<3C&1
@r967
GAAGAGCTCTGTNTTTGTCTTCCTGCNTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGANATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCNTATTGCAGTCGCGGCANGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTNGCNGGTTGGTTTT
+
FA>(A4>F+'8:="&G+C0)%5?6;&@#'.+;:23%17#C4D5DBE<>@6HA51D#(#>12C2,22@;";/"$)A#(B!5-(2*$7H8@.'E!'DG:C5)"E&)+='B?=(*B2A<(:%-"1!G)<)%D,:+:4())&;4<41521+*1EA%6+3D"!=+./9")@0>09C3C>:1<,"<"+$569-%"'4!))/H-AF<,95%8'549'-6C7,,F"'2E><<-%!B*(@H#?.A>/D7:.)3:%!==)F,/F''9*.//86C@.7)F/@!-H<)20'C$(2#A5H&$:&;H858:64(1>:EF*6"%G(->7&8-)495,&8$!,C0880<(*6G8++29!>!>D1*5)$/.A(2=.2&8H"D@
@r968
AGGANATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCANGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCA
+
))!*"'&+*!%++#%(&)($&(($)#&*)'"*"())"+(+)""('$'*#*"%'#%)(%+*%!*&*"(#$'(+)($$*!)+!&(%*(&"+###(!&!+(()$*&%%*%"%!)(%'$$"*(!"$$#&)(+'(&(*$'#"+)'#%!%((')'$'
@r969
GCTCAGGTGCCGGATTCANAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCC
+
5*$9<#<.D:E<1&+2=5(?5CG1"@>AHF;.&@"5<.F*A;<:>#,8)D!2-,+:B21&4:*E3:88#/
@r970
CAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTNACACCATCGATTGTGCT
+
1D=E+*:F(?<@45$":!,5'D+B?EF)6E#A"(F)A?+9>!7B.D."D,5F<1*#<ED<;,--$D85#*3,1C'=
@r971
AGACGCAAAAACAGCGGCGGCGGGGAGNGCGTCAACGGCATC
+
7<AE7,,2)G,*=H#%F)A<-()/6*'8">;=1;21:#<H:B
@r972
NCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGATGGCAAGGGTAATGAGGTGCTTTATGANTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTNAAATTGAGAACGAAAAGCTGCGCC
+
!B50E*4B;GG'!?H.D4E"6H418HA$,?5'@-#D$:?!GHE5&*.@?(9=28C!E'>/=5"670F5;-FB**2)%7"3BH8C+?:?343<H3&186#4'8,C%6C!-C8C0G%90'*6/B@G$260$@1<8<&?E%",CE"=)>!AH23@0$;E;B>/5B8<''?!4.GE-%$:#/A"?2/B),(&".<1$"7D/#+4.1@4;FG8(=@E>E?8)*94&
@r973
CNGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTNGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCC
+
*#$+$%(%#!!#(!*''!+(&"!%$'"++$&(&(&*)$!!))$"#''((("("&!($$&!$#'%"&))&(#)''''''$)%#(%"++$('&"'!##%#%)&&'*'("$()%
@r974
GACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATNAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATC
+
F)+A9<77?","EDB)7!!A<84'79A9)%E2!)5//8A%-4>G?*#FBE50=B?,"C<&H#)*>,-5:%/52B2363GF+4><*6H,/!=FGDD5>1ABE
@r975
CGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTTTGAAGCGTGAACGCCTGCATTATGTCGTGATTGANCGGGATGAAAAGTANATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCAGTGGCTGAAATTGGTTTTGT
+
!.A7-<AH"@>B.AC5H96>,B>D.4&,;0G;!9>66@#6G@*1=)F!1=,-!F'HBA>1&=4@E3'3>*?5=H"$!)#,#8%+'(:)':9@-.9CD103F%(CD;B$!F>))>!5/,;*H0H>?E3"8/+&.H!B#80,.#(.B&E0'#$,@-H,;+<,3B>#H%)9-9("
@r976
GCGNAGGTNTCGTAGTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATAGAAATCAGCGACACTG
+
!'*&$'#)'+""++#+$)'($&'&"++!("**+%)+&#+"*+$'&+(!'%#%*&#%')"(*&+"#)+**!!'"&+#
@r977
NGTCATGCCGGTCTGCACTTCCAGCTCTGCAANATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCT
+
%9B*-.F,H+E5*H>?GB9'B$&6?FD::/*7E6',B:+/&!4B-&G*A3@A%51%D-=%*!1B3/@9;CF$/=-=27"@&D=!4@7'*6"B
@r978
AACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTATTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTC
+
G+5F6#)$E=026!G#D2=$&E!AH*BC"07D->!FED;()6??E?%.)*1A2B,0=4+C(5.(@AB.<&'7C)>1DA;8/&9!;%=2>8DB,=*;+&*4G"+$=
@r979
AGAACTGGCGCTCNGTGTGGCAGAGCTGAAAGAGGAGCTTGA
+
5*:2:(/A%7%)%06@#&E:D=44-.>B$,3,/$"G!-09*)
@r980
ACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACGATGGATTACCGTAAGACGGAAATCACTCCCGGGTA
+
B)*6DB2/27H5!/?%,1C/G*D.;69GD*28%BF5,D-3#..<2'BGC%-*(2B23*,!$!7&/18>>.)-&)1G03)=!,A0),@?G$8*H#%4C!/81B,?#@G'B33?A43$-+&4#FDD.H%?2:B-"G./BEA+(H@B&&EH@E7,%1;()8=H8E5:3H5CBCA18B;
@r981
TGNNNNNNNGNGNNNCGNCGAANNGNGNCNNCGNTCGAGGNNNNC
+
"$""$#$#""!#!#"#!#$$$!!#$#!#####!"!!#!$$"""!$
@r982
ATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTG
+
C/8'(0?9F-9:+)#488:7!&?,%>@9.@B%+"H0C96F3%*$
@r983
CAAGCCCTGCCGCTTTCTGCATCAGCACANCATCTTCAGGNTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGA
+
7+62#+3/7?&+*H?86<1/4,'4.4(57E"/D;:<08AE@0(!133,ACG:'3'$7$(@;=0?2"1(;F0D)+)
@r984
NAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGNATGCGGACGCACAGCGCNAAGGCATTAACGCCTTACAAATAAACAATCCAATGGGTG
+
"@(#>%>&':16F>)CC.?.*/<0B,8=D5#(&,<"07:5.),;;,5+@;=133:4%'?!!?%#;,(<-1>1%2'5H<HF6&H!B.<$#4H@BA:=9DF"F24G,@$7)3?94@$B"-".298-8:E8FD;#"=/F<>-@@C'@).&@:B
@r985
GNGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTTATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTCGCTTTGTGG
+
#)$$)+"#+"$*"+*+$*$%+)%(#%%##""%(%#$)(!"&$+)(!$!'$$%&%*"*"!)$)'!+&!(&$%!!!'(#&%%!#$+#('*&'($&"#%#!%*#)#!#$"#$+'!+(#++&(!)"&&(#&+"$"!"!+%$&&)"#$#'##*##)'
@r986
CTGCTGTCACTCTTCTCCTCCTCTGTTGANTGTCGNAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCAGCT
+
-4G++!#37<"C)G.#.37!.)??6$9A/)=&;"D4@)<05FH2&!"$49=,+@E?1?2F64CD-&5AD=G$-G+E80F<+B
@r987
NGATNGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCNGCCTGATGCTCCACTTGAAGAA
+
#"&&!++*%+)'")!"$*+"'$(##!$"#%"'%&*%"*"&&'++*')++*+!(!+"(#)"&$$'*&(%$'&&#*#!"+#+!&!%!$((%+((&)"+)!&'+&)*""(&('$*"*&
@r988
NGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATA
+
#(,H',</EH2"=2DC="+GFH&C<!??&/=%E('H47-BEB929!%E05C#!E/+*<C8D3>3F80@H)'".H3(@-38'9<(B%>3!-*:G?7BB8C7F/"E
@r989
ATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGANAGAACAACAATATAGAN
+
6EF($1%*:@#13%>@&6C2HBD.+*97?".1)!F+D'!4=>3$;H/A+"@";".H64:%G12@>G))A(<G9:F>G69=*?3=F>-!$%B(@
@r990
AGCGCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGCGTCATGC
+
';#E&B4%5&5-,57;?AC((:7$F>!?0/D"(B;C;.+-8%?G=;G=?;
@r991
CTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGG
+
'F17'10@-+@>HA(@=AA3>2B+%9/7@7%,6E&5&(-1=C2/)5+,A@
@r992
GGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCAT
+
>?)+-)/9&'C8/9+&G@?28"%EF7E?(1:+32,>9#/39@#
@r993
CATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTANTATATGGTTTCTGATAAGAATCACTGCAAAGATCAAACAACTTG
+
>-'EEDHD/<-5>+01&6>%)%5'$@#.*+8(6917='414AH'G4-C)&;@0A&A?'B1$'G-:F)")%"+:5,$.+5;2G443,G.$;AB99<"4%8)26-:=,5%213DE&.':"A'7>0C1B$/B3G=A77'26G4!C5-(H:?"39
@r994
ATTTNAGGGTTANCGACTCAATGCTCTTACCTGTTGTGCAGA
+
$'&%$*$&&$#&"'+*"%')%!$%)"!'!&$((!&#"!!')'
@r995
TATTCAGAATGAGTGAACAACCACTGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGAT
+
*8'C>;<0='@<.72#C&".6'D9.A-(0@(H=2!30A&=0A)'7-A7*2+0+;B*8A:5:/9?2G:"DG?$!@-=28'H860"'$'1AA-!6;-7%D)-HC.H#.:>@7#9C=GH)B+*2:A9.5*62":#)6,'$E&AB-7
@r996
AGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAAT
+
(AG3<(=4273-E"789"$#B0@@A8*&B0.&-8(73/),A4G%
@r997
TGNTCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTNCAGGGCTTAATTTTTAAGAGCGTCACCTTCA
+
(!&"+*%*(%$+&!%!)$$#)!*("$(*$))''+("$('#%'&&#(!!+'%"'%$)**""#'')!$)'(+%(#*)%"%)+%*()'#!+#!%+*(*#+)%)(&)#)+%$+"(+""!(+""(+
@r998
NAGATGTAANTNNGGNNNNGATGNTAACANGNAANAANANNGGATNCGAAGTCCGNG
+
$'*&#"&%'*!!"&(!"!*$(!&%%$)''&(&(#"$$"$"!"""+#*)*#(&()''"
@r999
CNTTCACGGTGATGGCCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCA
+
)!C6!:D>.@4=#1=-=;E(H;/),E%03/";;.1&!-@)713';)A@5=5(8"=%C7/'%:#77"3$%HFA/?6#,1<,.<=<>H-&6<(05:0G9E,F6>28*5AG7-%"9!GE%D5D7<--9>!.-(GF'D4857H@79;?D#B2++#!@(2CE'A82D7/3.+,=A!/!6ADA(!GBHC:7&)#E3G'-&&2-(4-D+>D+8B+#9'???7C
@r1000
GCAATCGACCGTTGCAGNAATATCTGGGCTTCACTGCCGGGCGCTGGT
+
?1-">!2C))$H;D0$%*.E=/(#7+6+C-%*%A$>1HD)=%<+2"#/
@r1001
GAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGNACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGN
+
+"$"(&)'+!+"!!+&*+&*'#!!+!#!(&#*+*&*()&&'$%#))+"#$*"'#"*)*+'$!+#'%!%$#**$%&)%(#%!&#")!(%%$!*!&++%%($#*!')!*('&+((+
@r1002
CTGTATNNNCAGGCNTGANNNGNCGNNNNNNNNCNAGTNCGGAATNACACTNNCANCTNNTNNNNGCNNCGNCNNATGGGNNCCGCNGGTNAG
+
$##$###!$"$##$$#"$$!!"!#"!#$#!!$#"!##$"#"#!$!!$#$"$!!$#"$$$!#$$!#$##"$!!!#$"!#!!#!#$!"$"""!"#
@r1003
CGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGT
+
5%F"=H3)'!?G8#=1:1D?";=&9E7(F9".:5%,H1?6(1*;.?3-3
@r1004
GAAATATACCGAAGAGGCGGAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTNAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGANTACAACACGCTGATGGCGGCGGCGAAANAGGATTATGAAGCGGCGC
+
%&))('+#'+!"!*$#(&&!)!)%$&%(+#'(!)%"!)#(*$)%)))")"#%"%$!!')&%#&#*(&#!'&!!&!*+'!+"+*$'!*&(($$(#&*$")&)&))$((+)!%"(*"'(%(%()'%$$#++%&('$"%#!!&%)"#&#"(**$($%((!%$(&"%%%%"!('
@r1005
TANNGTGATTGACCANAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTAAACGTGCGCTAACTGCGGTCAGAAGNTGCATGTGGTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATNCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATNCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGANACGACGACGAGAGGAGCANAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTANACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACATACCATGTATCTCGTGCGGAACGCTCGTCTGCTCAGNGGGATGCCGGACATTACCGGACNACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAANCTCGTTCCGTATCGCGTCGAACTGATTAGCCG
+
#'"!++"%**$%&*#)&*!++(%'')%*#"')+!!###(+*$#$+))$&(&$)!+!!"!$"')#%)$")$)'%""&*(&'&+'#*"%'%!%&$)%+)#)"$+))!*%&#!((#$'")#'#'!&*("+%)!")"+*("&"+"%*+$$*++(#&&%!*#$%$+&(%$"))*'#+"*&#")$!$&%%#!%!'#"*#")+#*%'#(&#!"%+"%%+&#'$&!'#&)+$*"*&'$%#(+'*"#%*#%)))(+$(&%"%##)&%($(*+!&&!$$"'$)$+()(!(&+!#+""#$%$!+'%)%!)'%(()#&*&'#)##(&#+!*%+*%*&$%()&&'%*'"("#+'*+("(*!$""(+*%)"%*%)$&%!)&(+'(*!)%%)!(+''&($++&%*"!*"%%&"&&'+$"#*$()$'"&'***%+++'((%$*'("""(+'"+%#*$#')*$('&&)*"#))&'(')'(#%!&#&+#"$%)#+$*)&"'&*+&($*!+(%!)&!!)#%&#'%)*'"*%$'%$%%&$'$+(!#"$#%*"#"%&+'!*+(!'%&$%!!!&$(*)+'+'$#*)!%&"$"+!")#%!!(!!&(!!!)(&+##&!""%#+&"$!"")'$%)"%()"*#%$#'&#$+%!%(&)"!#&#'(
@r1006
GGCTGAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATG
+
6,-/F1'"@.B<8(B-;8:;C74*)HG*;BH9-+>7H'%!%D3);*%+16/E#>+5-,)8#)>9A<#*'!572E1F3!<-974
@r1007
TCCTGGTATGCGGATTCTTTCTGGAGATAGTAATTAGCATCCGCCCATTCAAC
+
(6<E3G62!#7=(4"DE>%98<@<D6$&HC6:842->DE?%71::+>='>'D0
@r1008
TAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCANTCGNAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACG
+
7AC+0#(,9HE258!H$%94*/6H+$EF=*B3070A44F*H!-D183/D;6FB>$2:3C%A.CGAF).+1A>HH)/B"C*('&6B.,(:%:6-,=>77?AD
@r1009
TGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGC
+
E>7BC8:DB1,'%B%(1-B$3->"7%EH)")H@A8D%#%:81.#0=3FH=('<H$'"#&.4:-%?
@r1010
NCGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTA
+
'1;11#/C/&8#3G,@+D71&$;%30-+5"$&!2<B7/!!=)*HC-"'/E3%3?!/%H,,#D;9F(3*F*1B2(0H'C9"9(><-#>@?018CF@2<":;63=906E+=-'2#B@4A#*,0,+$5"BB-D69>
@r1011
CGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAA
+
2(@++8*$)?@4$#BDG?&!2!)E:B1.C!F'A.8!38!@==/F@>@4E!=?$59!6'2H%(G*20#C7?B292)D3C@4'5B(<E&$A+;)
@r1012
GGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTG
+
=B'"*C=?3=EG.55#;ED,2G#0E>%B#D0"E2A-%"E0.A+B-9-E+=$9,7@&<5G<"-;E=7"/-H:+5/A9;:B4"DB96-6DCD1,&,A""=D5$':!4122>>=7E;226>!$>&;$:;+8#)<#.9*E5;*A>C1@)*7(:5@:-<)?)
@r1013
CGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTT
+
ABGC)6G:>0<1B937AD;9E!A12-"G7D!?$6(+6:A40*%*.1",>02E
@r1014
TAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATNACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGA
+
F+.!.A8!6:0$7A9-+$45&7ED,=>!+-0D@48/6CG;1=?*&=0G@@=*24>4:-9%3:23HEB1+"=("#2(AH/77C%C&!@+"*.B=%:54&</)$?9?:&1157@&C%0%H.))61816.;7-6(!$?390"6F@67"7(:H4@C7/:38DH,9'=*,#?1H=)53<'"=+7G#!<8&G9DE3@*1.8692FHE10%/97/.?%$>92H3>A7(.+G<96=02'$9?11)))CF4,,42A5A
@r1015
CANTATGCCATCTCTTCAGCTATCTCAGCATNGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTT
+
5A!@,"4%C-?5,&1#EA,#;;=.$8A8=HA781E-4:F##<C%(#+?%%3.E#-%0H$8)7AGB-8$0*3!3A2F8:5EC*BB:&:@!?0&D9G*.H::G:3=11?4%(!%A@08#808)H7):-,B4:3G-.4=.:++)',82C$:@847A487=)G:/!?:".-
@r1016
GCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTA
+
@@?/==,>;FG(#+D3F6D(9/D.AG>(B/%'#%1D;75%3-*"C#"525B*+?86&29<2F/(5-3&&CG=3?FF@%7,C%/16:>D*+5'
@r1017
ATTGAAGCAAATCTGAAACCTATTATAGNTTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCAGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTNTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAANTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGAGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAANTGGAAANCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATAC
+
E5$&E*;4!C;#3?9D;:%$08$&?7**89%4-=ABB:-,(,6(!$B(&G!!+/>=;8@0D(83;!B*?</.:@C6?H!"(B)9..35H1/*+1B+1B3!';*(@E@#)G2:'52":D*(AE.-52);A*/#*6*2$9G<;B"98(&;8<H8<:C6G/,7%$(84:*>H.<==43'"?.8?B>3;C<FC)#@'10**0)18-$*(@EB2E$2E//#E%$G<(!F3)GB;<8*@83,95#61AF";8E!,=32HH7?F5%B$3-4G$:DD'?)A4<"<!.D9?E$G95)=@"32A?'478E0EB:>8446AF+!G996)D%>97?F*7B48HD;16A,D#58H-,>H'4(1=4=>B#.8D10,#4)>,>!,$?%)?>*>:)3;(=0.$4!'#1"/2#G-F9))($((0A;&9)F"A!4@'E=+1-.8$?@@1+;!7BB<;*59G
@r1018
GCTTGAAATGATGAAGAGCTCTGNGTTTGTCTTCCTGCCTCCNGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCA
+
75:+C,4$H%E4+#FB=;!0.>(2=0.):4/27&):124)$=F*(D$-H3+::9@'&B,*5,?."-AF8@()5>4'!+F?';B<*5>CD87C2688!5.!(HC.(1B.24H:
@r1019
GTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCG
+
=0219#G/+AC.8FG4/5?1("3GE8>2*4(8+,CG==B#045:=5C<?$9;$B-6%"D%C+24E"5$0128,:&+-8(74/E!!(B>H,.04D%'%F(-4
@r1020
TTCGTNAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCG
+
1*:*$.A2@G$#&0=9B'8E'@)?C6><D4B/H0B23$)1"F;;@#58G;&D8
@r1021
TGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGNGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTG
+
A-'D5E)"(&#*=@6*?7>$$&8=D3;6=2#E%+67D9=:5)4D.61B64.:63*$5<**BA%4/+G;048>F6$7#"+66@CF8FD31DE1
@r1022
GAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAACAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGAT
+
.G7#GF>@/G;F02(HB#AH&5GD!"+7?":H3F3C0A(8&!=/)")C+'B&>63:1:;0BEA"67@9<F+0<(DG"(%F?>'%G&/5)G"G#*&:@B)%'CA!C!/F/EC*$.2G8F-E2&0$(;4,90<=F*1,0=$":G6<
@r1023
GCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCG
+
,A#B-)5'=0"26#A5'A'AC=9+!>(!E6=(6CF$A$D;8
@r1024
AATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTNCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGT
+
2+<,-GC28@@=93-2%15D:F=AH>&)!?".7;6C8=*233"#2?>A@+GDB;,*D6.C+A=(470G$*F?@&AD!$".'C2H;4.C4:<0A%1;'),??AH=&+2775G*%E$,BC,<6GC"
@r1025
CCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGNGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACACAGCTGCAGAGTGCCATTGTGAAGGCGATGNATGCCGCCACC
+
EA?&8<49)0>)(5>/-)--;5!/.)#ABC/&4<D49?2?96%A,)&H,ADFF%,:F760%"GH<H3%#B+C(4@&!F=+B6H4+9:B60D0'4CH'..F,C/&+='!$8)5+;)%%>@242DB1*C5.&FB(/$!G'=05H.?:*,.?-.!**06%<$GB>11
@r1026
CATATTTAGAAATGGGCTGATGAGTTTCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCNTTCTTGAGTCCAATATAAAANTATTGTGTACCNTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATG
+
<C121)35-%-.;BD&CF+E736"=-BB10(=83"6$561C?<F56!@/6AD@-E(=2&;6%.1HC6G/@,83<C>0)$C=-B10@!/EC4+5F06"/&1><@6C1%95G.>*A)8(:'5-+,C'01EA4EDA1@21;"G3?&-F8GFB5EH%*.*<.A:$&!$7F$5?8F2H?<2=+&/2D2A.C'#?A)<7:?1#!<1/E<0D>E@!.6&#)H0@+F.@BAD:8?>''#*)G6'37#*65&D1F2E-89"-
@r1027
GCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCG
+
'58,5)%E:&'6(/5&1>.#G''16-7<$G.B:6G.9$)-&(.60F3#)2H:%)(B#%%E63'$;9(9>:2?E7+9:GG*:0D6GHD%#E-6"E"3+34(6%(5A#<'-.$A+9?H4/0340G>8@F<@664H@CD9
@r1028
CGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGA
+
3)>F<2:2?$<0G(!&CF;'F<;AC/CF.D93EA@;C,C.$5D!>G5$@G0<E*2A(<07$(<!$G)7-9:12-,&<@+F7'9
@r1029
TTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCNGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTG
+
.@40*D@')?<//F45=2>>%;<8;!#$C1;7H9%5-2<D-26F472'/GD@4$9;>E<A=4F&?,&GEDF!#=E-A5#1C>F(<5H?60(0;"7HF7#?EF+=(A*;0$&HDD-<"0-1A:FH$4G"?7(0D#@GC;(1E</!DG$:@=%+25$45&EE1(D.EB,)+'%?*9676-3%()(?#@(#6A<&(&)3:1030*+-!1#H6+;C5BH!'C?75A:%HA41@F/=8
@r1030
GAGNATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACC
+
C',F&&H2?#)&*2<0,=)A-(E-G5*:2"'$@#AADA@9<5!C'1F<)G12(H,?7EE-G8+H)7+A5/4A7'!.5/#D#<?
@r1031
TCCGTCGGGCAGTATAAAGCCGCCATGCTTATGCTGCNTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTCCTGCAACAGGG
+
E2#/1BB=334@0"15H'45*4/$DG>!;547B5<(1>.EE$C:-.@:0!;42*G-A/:9)3,:<BE+1418B.>:('@<3A!F,>$8*'FE-1$EE"3;F)>98=*$C#
@r1032
TGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACAC
+
(C26?7BC'(8$%'F/#4C)7"D'/*1,E@.4B12,7G>D*9/#*<3-1F:7
@r1033
GTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCA
+
);C&C(:<2,*0HG($)6DA,8H(%!0!G@B3FD.D3/=))9.G77?;!##9*8,FF>&>"<@D:7D>G1*(@$3?*=F)='%7.!6DD-86&)
@r1034
TGNTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCG
+
%'$/&C831%$<*>;>$)":<=D1E*)HG;?94;;-)806G5!6%F.6>:$5'02AG)%(A33//=$;&G.DG7GG,8#1-H<9CDE'A+05
@r1035
CAATCACCAATCCAGAAAACAATGAATATTTTTTCTCTGAAAATAA
+
(A.&'EC!HGBB;"!?:=47G%E7!"CB"AD0E9@34>4==#:2:0
@r1036
CGAGAATTAACATTNCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAG
+
*5#@0)D'=)5/<E6B$$:/(5)5G'&F6>+7H3@<02H=H)81?<4)5@F5'@A1('3B2/=#E1DCH*!:'67G
@r1037
TATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGAT
+
(A75?;/F9!;AHD&"33,.=1188G),668E&H3)C<,&#D?C,#?>>7).5'?6.%%C="*$&.&AF:?--H%='+8$908<(F#'$)F,?!4,C
@r1038
CTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGA
+
F:F<$>9))FBF5?%48&;+;?:"$C475%?H$?<0"5B.,@
@r1039
CCATTTATCNACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTNACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCT
+
7-:*A<'&!#9<5(4B9G/=2F)9D>9!8/@):H9!8:0!0H'F6/%:%3)3)?10$H$("-)H=<C"#6&93*&2<,&E/0(.-,@?AB),4.D
@r1040
GCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGT
+
C6!25%'F0'H-2#F"H')A"*>4)04G!AE'";.85/.#:G-)?&3$><)55-G=1,
@r1041
ACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTGTCGNGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCC
+
G/@4G@C)%<;+=)H5A!D2,10AFE%)/'%12+1B914<>G"&H-*?2C)+F5%730:)$A6&+!(--6E=-%.6:#;+@9$54)8G!!;5)&(%&1$<C%/!9/2
@r1042
TTAGGCATTNATACTCCGCTGGAAGCGCNTGTGTATTGCTCACAANAATTGCATGAGTTGCCCATCGATATGGGCAAC
+
/@.8<*=!!@D()'9'0&9?1?8'F+9<G";F7:520,7",F.@(+30@(9=40G;<.504/4=(/2E/7(>A<9:(@
@r1043
CTGCCGCTTTCTGCATCAGCACATCGTCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGNAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGAGTACGTCAGCCCGGAAAAGTG
+
+$)+&(""+)##%((!'*##&((++(&)%!'&(%#(#$(%!&'!+##%+'+(""((+$%$+!)%)+)$)'(("$*&"(&!!$%'$"$%$!*!()$()&*+%$'(#&$%#!+$)+)!"$'!+)%#(!"%*""&&#(&$))
@r1044
GCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGNCAGGAGGATCTGGAACTTATCAGTAA
+
G>'2*A:<*)+)%+58/:2>=*(DG=EF&?&;H24FH2AF%3A8*&6-;3.%").G59B8!,58
@r1045
AAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAAC
+
=5"C#@CD2"'"%8=A@"?-FC%9<?5)C3/C0'23:*2+)<>7
@r1046
GTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCA
+
'$=>41!C6888'1<7>3$#G*A59'>:.'A)3<A#(<E-F636755@0(9F<?BF>.+E?B
@r1047
AAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAAT
+
0B-E?7;1)>9E2!%5,"-!(E-D)%'-*>F'3,H@%)$(,)//)#F/5;-9G#5;.,?!:A:$C/&F?%61"HB
@r1048
TCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCT
+
#96*HB)G!A:#=.G*6C+:*;&/$6:'?7HB9A8-30366;
@r1049
CGAGGNTGAAGCGGCATNGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAAC
+
+(#"%"+#+!%'"%"%"&&'*("&!(#*'!*$""))""+*#+"&)(#&'!*'(')%+""(%%((&%#%
@r1050
TCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCA
+
@*1**$$0H/0H00>?3D>BB!+F-5;?..>B<C"('-%&&>1'4%(&0F17()!GE9+H$)
@r1051
CAATCAGCCAGCTTTCCTCACCCGGCCCCCATNCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCNCTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCG
+
:6C=+@@C.G?C*9C'2A/*+(D6414-E5A%>74F&>,E;/)$AAD.&<G1*DC/$7F08E:H&"!<:&/*<;=+';DE;F&./G:$'%""4/:9/7EG)!"+(2;:G-85E@(54<#%!8+B>C+&'/6&BB!+)18<.A/9670=C"@17A02)"%&%H298:4B,=H&D0;B:",#?=&<"+(FG-F8
@r1052
AGCTAAAGATCTCGGCGTATATCAAAGCGCGATNAACGCCATTCATGCAGGCCGAAAGATTNTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAANACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCGCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGT
+
558-F1#=?FA4>@>??$'B&+"$D@,G)%%')!%(.8G!8!G--9='36)-54DG!!'"0#3E.9A48=:,E8#214A=1(-=&F;E'0A39@A7,BD8GF4/79GA'>894?DGD)->%-2!7/C7-=H-+')3FC,1(8'>(*8@&#ECC%,)&.?./)5%$H.E(7:C9'3C5F@('<$C%2E>"7""3EG@*&72?:5=F75
@r1053
NTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGAT
+
(87&C00CB%,$F?=&>@.EDE"@#)!D@!F8;H+),&<C*+368<-<,,@C!'F:%>#+D8$7(('5,-7$20#H'0BG"0HCF*54D(<2*95E1(031$A=($EBD'/-7,35)6,'C6H?37"85)!>E8-%"=:.%DH)4+!/-!/7+G/&"($8'A3B8%5)F#,H88DDE814D<</,&,F42+7C?B;0!"266;G(6FBA5CG+:;<$?6#+C<11&0,.!E,6'0
@r1054
GCGGCAACCGAGCGTTCGGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCA
+
H>H52!6/GC1(#!0!."%+2G#75/92B-49&2(D-!$A80<?)A0.#;&#@;,A*@8,=72"4=9-'A3&!$2B07*!@A0;66-4>*F?7"4@%"<F1,;7E2-G6/>-+%C>D6$<%CE3!?&:?0'>''-:3(>/EB6>.3*#A(2$,9.G%+/G':=D+=*E>CA.G
@r1055
ACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGT
+
+;;AHFD@C,:642>+7$@D4)!*'3D6#'75+?C%CD1$?'
@r1056
NGAGCACTCTGNGGCNGCGGCACTTTTTTCCGCTTCAGTGGCCTTT
+
#&()#(*""(%!&&#%%+$$)*%+*'#!*#)!'+"$#))"$$)*(&
@r1057
ATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGANGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCA
+
+)(:3(%3D">D"0*%:D;1='?7*/"0<6)&925'10<&B4D1+(@6G;'';+H'7!C:@E0.&*C<+3-0G=8>*93.3G4'97;A>@%:%C77813:2928)E=.E-<38B&-;#$A>@/">7,$3H*45*4C%5;(9*"/&3:".:B%6F')9H2+)A2(<8:4&8G!BD
@r1058
CATTAAATCAGAAAGACGATGGGTCGCTAATGCGCTAANAGATTACGAATTATTACATGCCTTAGCTATAATCTANGGCAGAATGNATAACTGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGACTTTTTCGGCTTTTTCA
+
!!+)%#&')('""$++&&)&!$"$()#!$+$&*"+%$!%+!"(&#"'%(%&&#$+*""("$(&"**'(%*!"($*!)$&%!"&**&$)(#("$*($'"$&%"*!+)*))*!""#")*!#*)$$#%*"&'$#*$*%*#+"#$#*+!'+%#)+&+#))%
@r1059
AACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGNATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTC
+
?$'%A06'D!((*D*5,9B#B8!G<73(?ED;'%)E2'8B,&?F23>?3,E?HH2-&D(-1E&B'1=>07D&B3.7=0124C*&@+5@(''HEC"1#A'%*8##$@58@1>H;*@C
@r1060
GCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGGTGGGTATTTCC
+
0/+&3'*.;G2-!:G'"!=@62'-2*63;&:%-/*G##$A(>G:)2F1C
@r1061
CTGACCGCTGTACACTGCAGCCTCGGNATCCAGCACAACCT
+
,0.7E024G577-"=3-'901EH+3)'0--@H*B$H:75,%
@r1062
GTGAGNAANNAAAATATCACAAGTNGCTCCGANNCNNTNNCCATCTGANATTGTTCGGGCGNGCTACGTCCTG
+
!)#%!#(''"'*#%'#%*((&&'&"&'$$*))"($##&$&&'*($"&&)%)""%#$*&"%$!+&!*&')('!!
@r1063
GCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTNTTTCGCGTCANCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCG
+
4?-?2F;!H#!;&A2?7(9%-H:$%;C>31;-GE*6#*HB!#F>0.<.@&#6$D9HG64C*?="!G6";*(/$',,1D+$!;53-/B:6&4/;920'<*.H.("@%E*.7;?,'$,/;<@B(6&E:$A52*,5.<#H$?>%C%-<;F06H-!7DD<1756+/52F6/F?521;3C!DC<2F*
@r1064
CCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGT
+
6B)$CC&9/5*B$A63F:=6/0"5;,C8'"1EF42!0HG$G.A5D+0A+3*.6$2,/A*0A3(-#0+,BA741'/95,F5<8/%(C&G02'E/F(F(2C?%*:<7C!
@r1065
CNCNTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTG
+
C!'F*;9+1G.$:B=0D?0#BAB>)<FAB5A6>>B*=:AH2'#,H:9.1868:E/:-%'98/@FHH6!=45.02!
@r1066
GGTTCAGTCCGTCACCGACGGCGTGTAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTT
+
A.?#G..*199;$,6HF62.10$3E>?/4D-E!F85-A@C9042,$"64F569$G=*#
@r1067
AAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATNGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCC
+
4'*77)83*0G?;5<=*9C8218/89E':":@3!/-!<H/+B0:#F6(0*@)+FF0G!1H)-&0A/&;(=39D5;.,#19G,$E!)-CED%"?E,%:>E7>H9+6+16531
@r1068
AAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCACCTGAACAGACAGAGGACGCCGGGCCCCCAGAGCCTGTTTCTGCGGGAAAG
+
-0"8:G)!BH7F6G#!E7((HG61=(=5?G6;3!(341@;9!")9"GD,=@+'2.=283*+DAE@5(+15->4'='35BA)+/79#/?@:+<3@&#@80$,CG
@r1069
CAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGGCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCG
+
*7HHB;B&1E/64A#9,/&26G8/"8<5?;6G83$9-7:F-D1.F8'?FF/=.E(#"7=ADE.:>G#.G+-3>(85&D&(/5;61E8%3+CD-81F(A6$*627.)$76F/C7:
@r1070
CCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCG
+
'C&"=CC,G"B/F7F+09F*.9?.!&H%<?(<C(!(<,C/"7;695?%!%%:2;8-9&3@
@r1071
TTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACG
+
77#:D@B.>*'F#$0>46?$2G<"%"&++>D4(E4@%/<*.;=.@;'G;GE(>>37E$-F::70F4('1H&6/E!.G?@87#=E**A'5?=@"6=2F
@r1072
GCCGTTTATGGANGTGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACNGATTAAAACTACGTTTCATGCACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAG
+
***!"'***)(*"(%+%#%'($)*%%##)+)%"$$%'"&'(+%$%&%*#+#!"(%!+(+*%&"#'%)"$)&$'##'!%###&'%%$)"#'$"&("%(#$&'%$"$$+"*(!!&(#**&(*&+&+)''#"*''#+$"*""#'$)$*
@r1073
ACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGT
+
(FGED(DEGH+('1*1+6G851EA,1,;:G;<E+)&D!4;':'AA+:/E@:=8D;56G/
@r1074
AGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAGATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAG
+
((B7-!>,?=!;.2+"<(D2>G;9@'$C(@4(-;H<3=*#3&C5$4*?CC$E1:=";@3.B4%>(<,32BC186'0F9>04'.;?-B&C=<<7/0"./2!A5*@.5,#''=:'AE(!,
@r1075
TTTTNNNGNCTNNGGCCGCNNNTNTTGNCNNTNNTCTNNNGGNNNCCATNNGNTCCNCACGNATNTNTTNNCCNN
+
!#$!!"#""#$$#!"#!$"$""$!!"##$"!"!"!!$!""#$!"""#"!$!"#$$!!!$"###!"""$##!#!$!
@r1076
TTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAA
+
H1E=H9:5A)?8+'6!&H'G=E0;1&0#"?.!7%$)1?:#=+1+=8%325976"4C"7$0".E%!7%+7$<E4E!5=1B*3H!<
@r1077
AAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACG
+
H,&4,53$!"A&1@<.!.6@=3@0&&8A;E!#E;BH2:%7'!=26&+.0-:>$>22**/0(0;:+$-0/3+8C5):D>71G,:"A7F#B>83
@r1078
CAAGCAGNACATCATGAAAATAATGGGTACTGTNAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCGCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGNGCATTATTCACNACAAACTCATAC
+
@7;=%*-B@DFF35@;8.:?(?++6&/D-59!5D%B.5&+9B=H+):6DHGH,-4E2)6E"EEE+'1%E/?@E.#=E?$4>8'8:2'"5"%2(+E9#)26$-@G3(H5,+C4E('E2411F#/0!D-(%,8@/FC.,=!!C!/"-6(0+97+<GF<4)-0$F:$(8HC'C"<54H$6=G*>;)-??=92%@7AF@.D2*@CHD'+(14)2.(4"/87BH$0-;<A>
@r1079
CNTAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAANGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGAC
+
!&@,DG+3&3H;<FH(42:0C3'?7%!3:9G'D",('100;D(>'0.,*2=GC*:7/3#;D,):D(E21">8?4&29B2.<H4C1$>$7;*%.D#@/0!)=D.+/D,/459168#6"A5<
@r1080
TCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCG
+
*D>49+-..-3EA!A08;-&*%32$67A2*+4EG50DEG4H,%,5*''E1=1'>):68
@r1081
NCGCCCAGCCNTTCNGATNNNTNNNGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATAT
+
"(&!*''(('"$$'('#*#!%""##&#*+*#!%'()!*&+)(*%!*(%'+&!'(!)$%%'")('#*+!*+')(#)#(&#&")'&+&'#)#&!+%$$'#+(&*%"$!'&(')&++$#*'+%#'&!!''*&"+&''"+*')%!!(&%$(())*%)*+%$#!#+'
@r1082
GTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTNACCCATTCCTCATGCTC
+
:<)+++6DDC5G5F22+F(#83&/;7*!9:)D>52A.&<8B(E+@F0H2B<0B2;E
@r1083
GCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCC
+
+;"B?C*/:B-3-=/&>3C<@;(>%*(0(B6;21&(:77"9:ACC7A-/8F1=,*0+4A"8/
@r1084
GTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTTAAGTTCGCAGAAT
+
1-0(C08%?%',F:#(>F6&=/48.)H>7@*51(A>F;4FF2!)3(G2;&4(--4.1%/(<@G#+%.G?3)E,37/)%B8CD*+C<G$:H#%/3(9))3-9+82
@r1085
NTGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCAATGTAGTGGCGGAAAAGGAGATCGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCNGGCATGATTCTGTTCCGCATAATTACNCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCAT
+
"(((+"($+*+%++&*!'+"""$!(&)!!$!*)('!*%!*(*$#%%'&)&""%*#!')(%(&&""("""'('*#("'+()'#(#((()!%+$"&('$"+*($*&&%*#!!'((%)'!"++&&"%*(+"&(#**&$(%&$##(%%(#"+&)*"'(&$+*"#!#$&&#*+"*''(!'#(%$&*)&'&#*(('&*"'"&+)&"!)*(#$##'&"%('*$('(!+)()"&*((*)*#)(*(++*#('#"&"('"%
@r1086
NCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCNACGGTGTTCACACTGCGGATATAGAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGA
+
!2,9$2D2796,3,G4+H1;GHAC$<<4&2%"8*$HEE/+/F>"GFEF#HEA-!+#1'&?&2!,2@)5E),--A417B=770D,F0(.&"C6BF#-@%7<!;G;96/+.%E2?F..D.E%F?,FG%'".*B@0#()$*9,CH*!("#$:A:&8.:)186C*,6D#GF:A8*AF&-(4"8HA<=$?"A@5(,(7G=4BA#*1CH@D4HD</A,38+1?!;C
@r1087
ATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGG
+
F6+H868%14%=HG.58/7/7;F"D1BF+G>EF7=BE+*97;F8;B2!F!$F2H69
@r1088
NCGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGC
+
!/!"9);%?+/$'3DBBE@84%6&"0/+&?.45?<5>HDG66.>5#5$"0!A*:DF;*1&%A@:BE11C'GG
@r1089
CAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCC
+
81?-G,HA2E)8>F%F)/43.FF+6>7*&=39(7>)!*,<5=>))
@r1090
TCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACA
+
>""*'!C&)8;,>;GA$2<(?.CA.2A)(F#9E2/?7A29=*C3"">G+4#4;!$=650-+.F8C2;4'&28(C?5<'5D)'#/',H/)*>>6D)6;GB&@/,*8!(7)"+DB%
@r1091
TTAAAAATAATTTCCTTGGCAACCTTTTTTATATCCCTTTTAAATT
+
+%'("(%#(%##)*%%#+$)&&$$)$"+(+%*##)+&%%'!')'%#
@r1092
TTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTNATCNGGAAACTGCTGTCTGGNTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACANAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCNCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGNTAACGTATGGAATTCTTCGTCTGTTTCTACTGGTATTNGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTT
+
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
@r1093
TCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCG
+
)@'/>33"A*+G$0!0=/6G$A>1GF=3@F->BH.5#@38:$3'@DDB'&C@;G9E9.-F1E3E9?,;.4?:
@r1094
GCTGCGCANAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTG
+
A(6/4FA=@G(A4!6+A8>B$?'%,3-4/<7,,.''1DB5A&=G3?&4EC@D#@%@>@:(&"?;@+%E;8/GFE-D/HB@#+&(C/8##B($4H+1-F4C1#+52@$5))-06"3=()07,1@?
@r1095
ATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGT
+
8"$($E2+6A=6.02@'.H$3%E2/%3AA4E,(.D2(@5/&>-DD%;#?FA)C(0(3<:=5'0'/.F)1G?@.;;H9-A13'-..H+F%E%?B>,2(4524D0@
@r1096
NCATGTACCAGGCAGCAATGGATGNGTTCTGCCATGCGCTCCTGA
+
$3&:7(<=H51=#;3*E<"H8?E)30%?2>;'--0C9,4)>885C
@r1097
CATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTCAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCA
+
@H9,++528+70&#9%6>B)A=@G8=28A=/2DF"43!;(5>CFH5=?4@'@9G'FH49H./!C.C(C/*'0>4-?1H&4GFC&;*9+'@E!7:%(8>5!+(A1@7&->48+*!,(&G+H8'B52D#+-)//+?9')>8'&G0(44'+67*&43'6A?'(
@r1098
TCTGNANCGANTNNNNCAATGANNGNANCGGNNTTCNNNNTNTGA
+
!#!!!##$$$"$"$##$!##"$!#!!""!"#!$$$#!""##!"$#
@r1099
GTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGT
+
08F;,F23C4$:$8?>:&#H4-&1:&&&C"<H-76E.-EG"CE.2;79&D<B!
@r1100
NNNGCGNNNNANAATCNNGNNNTNGTGCTGNNNNANNGTNNCTAGATNNNNCNNANAGGNACCGNCNTCGCNNCAGAANNNCCNNAANNNNNGGCNNCNNTNANNNANTTNNANNNGNCCCANCNNANNGNNCNANCTTNNNNNNNGNNTTNGTTTNANAGNGTGATGNNGNNTNNNNNNNNNNNCGAACCNCNNNNGTNNGCGNTNNNNGATGGCNNNATNNTGAANNNCGAGTNTNGTNGNNNNAN
+
$!""##$""!!$$"$!##"#$!#$!#$!""!!#"$!"!$#"$#!#"""#!""$"$!#"!"#"#"!#$$$"!"!!""$"$!!!$$!"$##$!###$#!$#""$$"##$"!$!!$#"!"!"$"$$!$$$#"##!$$""#"#!#!!##"!!!!!!"$$"$$!##!$#$$$"!""$#!$!"#!$!"!"#!$#"!"!$$!$"$"$$"$"$!!!!""$$$$$$!!"#!!"$#$!!!!!#"$!#"$#!$!"!""!
@r1101
AAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGNTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCT
+
G0$20FB!D<?=#63266A;FB:,$7A<.D>4'H+6?@&>"C0<EG<:83=(<==C:"<6+;9-CG<D>=DEH9D*92C2>62B+0@((E<3F%66#!-D-9=C1%+$+HD":EG
@r1102
CNTGATGCGCAGGATGACGCCGGACAGCAACACAGCCCAGCTGCAGAACAAAACG
+
&""'$%+'+&%#"!'"#!(("'%&$+*!('!%#*&**"&&*)))""&%!+"%+$+
@r1103
CGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGA
+
9';3A;D:E/'8:GDF7,A4F(?H>C#/G,(.6'4"5&>,H46>'1*'G?0)5*B+=FD>04C2!9!<H99%2D8B*$(.3.<"=<=A6!A0H!8<B+";(H9..A0C,-8D
@r1104
GTGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCAC
+
&&&+<)<B.$!-BG%&0-G"7EB&&6:>%81B6,BC+2EB0+,G"<)361A>4%,A$>36F-97*33)$G
@r1105
AGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGT
+
.(02!@(0$+A<'94,''+%=D!5'>@@@5+E7,E)3:>3#C*&
@r1106
NATTTCTGGNNANACCGCNCAATTANCCNTTACACNNNNTGATGGNNNNCANAGNCANNTTGTNNCNAATNAANCNGGNNNCNANNNNGNNNGAGTATTCCNNNTGGNCCNNCNGGCCGACTNNATNGNCCGNCNNTTCNGTATNNCAGCAGCCCNCNNANCCNN
+
$#$$"$"$##$!#$$!#$#$"#$#$#$##"!""####$#$""###$!#!##$$"!##"!###$!$#!!#$"!!"#!""!$#$"#!"""$#!##"$!$#$#$!!"$!$!!"!$""$$#!""$!!#$#$#$####"$!$#"$!$#$$####$"$!$"#$#"!!$"!!
@r1107
CNNAGNNNGNGTANTNCNNAGNTATTTNTGCNNGNNTNTNANANGNTTGCCANNAANGCCNGTACANCGNAAGTAANNNNCTNNNNNGCGGCNNNTTGNAGANCNACNNTANGANNGNCNNGGGAGANNCTNNTAANCNAACNAANCNCGCCCNNNTCCNTACNNNANCNATNNNNAANANCCNGNAGNTTCNGGTNCTNCTTNCNCGNNCNNNNNNNNNCNGTGNNNCCGANGCNNTTNNGNTNCNGCNNGATNNNNAGTANGGGGGTTNTGNNCANCAGCNNGNTNTNNAAGNAA
+
!##$#!"!"!##"!"$""$#!!!$$$!!$!$#!!"#$$$!$"$!"$##$$##"!$#!#$#####$#!#$!""$$"#$"$""$$#!"#$$#!!!$$#$"#"$!""#$##$$!"""$"$!$$$$##$$!#$!!""#!#$!#"#!!"!!"$$"!#$$#""#!#"!$"$!"""$#$$#!!#!"#!"#$#!"$"!""!"$$!$$!"#!#"$#$"$#$"!#!$$$"##$#"###""""""""#$#"#!#$#$#!#!$#!#!$!##$!!$#$"!####!$!###$$#$$!##"#"$#!""$!!#
@r1108
TTTTCTCTGTGCCATGACGNAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTT
+
B"0/A<6F("&1/?8!8;(6(3-&$(.<F'6#(C63/7+0;($-,8*;&"&;&,#
@r1109
AAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCACCTATCTCAGCATTGGTGACCTTGTTCA
+
64<%<+86."-%H'"$@'$D='&%+>%#A9$8+.*%C;1&B)6#:<*?@9(14:B,0<H2%E(/-#3C;/((*+?B6D:>1/&>E'-9?/9=@E55F+1!@A!#F??$!%B<&DC+4=;C!2$*)>23B06?5(D%=>%4(;:'D-6F233."(2+9A04;19;@B)>7"2FC;
@r1110
TTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACA
+
3/7F+:,'./$BCC>A#,&AFE#BDEC?F121';*!34-/@A>HE%8G!="G8%<:CBA?(752H@3->>.%9)3"1F?%4)5+5(-53,%B%3="A/E9G3):/1
@r1111
CACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACA
+
;$'@7A$:AA+,'=C..(&&0?"#3'+%:FD99/;B%-2&9@+E;@'D0<",
@r1112
AAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACAAGCTGATGGCGGCGGCGAAAAAGGATTATGAAG
+
+%#")("((+!(#)&&)%"+'(("*+!'$&$"")$"*)*"%&!)&")()&!"('!(%*&#)*(&%+$(%$"+$(#'
@r1113
GTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTA
+
+&#("*!%(()($%*)&'+'"+)'%")&"&'"''$"$%)+)''$"%"!+++$
@r1114
GCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTNATAAGTTCCAGATCCTCCTG
+
#$HF+1G;?94=7-</E#:4%5B(!,&554GC<33@A)A-9!-*+D+=,;3=1A=;>3.-(#.E91A,'
@r1115
TGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAAT
+
C*.1C:#?8'"=>D-G'<C$=,!!CGF"960>+&C:%@2)C@>1(%>%@@AH")A%<&CCD0@=4$@54C27$H;<<
@r1116
CCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGT
+
?/AH97A34%#$@E$6/>/5H5"B',*FD!=E;DC07(9#;@<
@r1117
ACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAA
+
<E/$*8)*&@987.@%!1%"6F!C21/G$..6H<<7;H&4A*'&,
@r1118
CTGTNNNCAGAAGCNTTCTGTNCNNCAAGTTCNCGTNTTNGAGTANTGCNNGNCTTATNTGATGNGNGATNCGAATAGCTCGA
+
)*($$&"#)$)!!&!$%!(#$*""$$&(()!(")'%%)!$*)"#)#*)(")'("($$!!)&(#'')#++!'$*(+%%#&!$"#
@r1119
AAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTG
+
5C>*$'1EG->BF&)/C2B7.#.%(%E1F?+F&*H145&8?;E2&=2>30D>.$.-=.1FH1%9'?A9%=9'"<7+F>'@497*6$
@r1120
AGAANGGGGATAATGCNTCNCAGNAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTNAAGGTGGTAATGGATGAAACNAACAGAAAAG
+
(%*&")()&%$#$%''!$)#%#+*%)"&!+)!!()))!*$#'!'$(%*%&)*(%"""%))*!('!%#$'+$&*$*&&#$"#$(')%+#$""+"&%+&(%'+($&"&
@r1121
TGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCACAGTCCAGTCT
+
(:7?=G:DG'67'7:*BH39'0".HA245:",1"E<E/7:%>>$!*?2GBH,22=/#5'E,+!+=$C>04)3)/D&2#E)43)@G2'
@r1122
TATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATAC
+
4--3+(%7H,'!CH89*/./@CA+2=,AFDC1-GAF=,5(;!G4-3D'##*"!H>A)-
@r1123
CCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTT
+
<@B:#1E1.2-:#&,+&<F;>7#195>D%2G7'9(;HHFF8B;!,#7'30(>+"3)FF#?0<*B04-;)A69H"A#9)-HE*G)5&
@r1124
CTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTNCACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTCTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACC
+
$BG,=#?$D'*4E0@->C5<-9-,7;-5"7C-8<2")(G1834.&><A5(H&89H"HH$:=%>24A5*/#>=%/G.>9G?)$;$H68?:'4(<!9H?$18B5C:F?C$G$=*1E"%AG,@/#H.:8!DH3D4B->49$H(B8&(2196!3!#EB$+0,:#44.7FB6/2F5#+A4B(0AHF"E9:*/!2$:)1F.,!;6A-@E(;GC@C13E!%G4&!;A44*(AF6?:EG-3:&9@7E&(7*&2.9#C9"*%68(<+*B4>?
@r1125
NNTCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCANAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGAT
+
!""#+))+("!$)#"))'&#'#%*)(+*'$)+%!(%'**'!)%)&*&++#$"(%!(+#$)$!+%"""'"!%&$""%!$"#*&("+)%"$!$#%++'(%$')
@r1126
TCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCG
+
90A&$D=E:5<H6+F29G9H%7/)GG7*'D@%H")GD134?@)CD;"$81!(=;,>16.>@/3:<BH"=B,HF(4CDC6C4;@2>%D
@r1127
CTGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCG
+
616G?B&C#1FH9=H/!5CG*<CBF=#86!+1":4$<&,7EA?!7H?0@>D)1,=;-::,!);7(
@r1128
CACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTNCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTNACTGTCACCGCAAGTGCGGCAAAGACAGA
+
305/=(0%5.&1-A-A6;*;(A!-DE9F+D7F83@/,G>9!F756B0D4573('@+:="74G3*$2'7C/?!@>%C?.+DE0&/,D%*!07%:<.H=00,G9G<F.,>$5C>FAFD;E<3H)1:3C,0,:7+
@r1129
CTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCNTTG
+
)'++&$($'"$$*%%*!$"$*%'("*))$&+()'!"*+'#"'%%+%*
@r1130
CCNTCTNTATNTTTTGTACAGAGAGGGCAAGTATCGTTTCCACC
+
%&"'))$%*&)&#'*+&($#))+*#%#$)#('&')!$"$"#!("
@r1131
ANCTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGNTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTT
+
)*"$+")$#)'*!(*)(''+!%%!%+$&##$%)"'%*")(%)&%$$)#*"'&(%*%+')%"'""(&%*)''&+*&)*("$)'&*&*&+"##!*+$*$)*'#%&"($&%!*%""+!!&&*#$)')++%'"+#!(###)"!!#)&%(!'++'!&!#)'$'*$"%#*'(+*+&+(*)+!"")+(##*())!*%*'%($!#!"#'((!+
@r1132
AATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGNTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATT
+
=-'2A99700DF8;,0E1@%-4;G7+:0&'G:GF1/B$8D@DA677:76"F='C'*@4-;3&8$13-224!H25-@&E?7D7DGF&G*(A;@G;%.9-:@62*,300;76='F>3,;?!GG(;1)<A9'>/B,7$C8DH;-##'(EB8@D"$/B88@71<*0,287H:27$*C'(E"/E>,7#656';++-7.?9@A&A1
@r1133
AAAAATCGCCCNCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAA
+
/<A725+<9(""%11C@,+<&.('9<:)5.=-9%1E:?%E4+)GA7!CB)B-E>B;.D109BFF6*"'(,<*A7@A/"$9-$28@E6($0;!+:87,4A62GD;-
@r1134
AAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCT
+
%G#,:CF,7</*209D=9%:G#3(/).,5!+36%6&0>*)@?/4%8*7!"A9-HFH0#2@2$3%/:(8<=::
@r1135
ACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGNGC
+
HE:)1B6)BA<*:-'G442;61+20H"?=;G*;1";=*,A&0)+3GE(9),)%F@%+C7F(B4C,
@r1136
GTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGNCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTG
+
*%&+$+*))')+')"*((&"&'*&"(%$"#'"&*%*&(%"*###''('%(*#"!'%%+'$(+)%$"+'+'*!'$#+)&"")&"*%"&"&"+'&)&!*$)"%+
@r1137
GAGCAGGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATGTGATTCGTGTA
+
+$)()&)*&*&"+#"!+*++()("%'!%&&'&(''&"(*&+"))$&+#++"$+*%!)%())'')"!+)"*#)%&
@r1138
ACAATACGATGCCCGGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATA
+
.5':E@"B-*32(=5<<4F3&H3E=/?"::4*#$07*E6A0)8(6G02($%:9><@.C1.#"'$)--2C!.;81.>@B?2;#0H9!+.@%6E#&FA&=3(%G,'9$HB)"G;9(8DBF+.;0"5/+F/)83'%H;HC,.
@r1139
GAGCAGCTTTCCCGGAATTACGCCCAGATGAGCAACTCCACGGCACGGGCCAGTGCGA
+
AC(3;)A"*)*"31<FG,20E#?4,(.+=AF2)B>0?/4/31<1;A$9%3=@B7%/+:
@r1140
AGAACACTACACAAATCTTTCCATGCTAAATCATAACGTCCGGTTNCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCNCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCNCGCAGAGAAGTTCCCCGTCA
+
-?3'@$(+*@>1-2B)"@7;"#A=AG/0&"C%&;+!2">1?/5?&@2!AFD=F1;.<<F-4=?0C#6!+@)--<*@99#$0;-B@FH;>*874D9EA"4'?+5'3:$0"EF6$.+BC8A2*G55"=$*$592+>2'-4/?;6@7B#3E4)#.4C)3
@r1141
TTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGT
+
.:GB#)3;$7?=##=4"G@=9H&CHG?@:.);7(AH?GC(!A77.>6&E1)/<F<(G-?&H#!;/$+4@3,<%8,'"<0A4E85=(<&E4??A%A6@#!G)!#9C048F7D-$=E<-48B''+'(;8%7"D>DE6=G/B:4(BF&F;)G
@r1142
TACTCAATAGTNCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTCCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCA
+
@?;:E>7E(4.@B<==4&&>4"?:AG"HE/!!1B"-;B!G%4+6!A>D42F5A2&$3D<5'GB$27;9G#=34?9BC/?C;6G26H+$-,E2',$E;:3;11BH-&!/<8.'":D%E"-DH&9
@r1143
CCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGC
+
4&$8$E$>610$=3A*B6C$1(A/C19G2#05F8,BD!%G&9GC&2C<'+,'C6&.3E6/@.D6H/->@;G6;6:8?),.@1'-5/CD80=+6:D:.$*4:0C7'"-E<2/E28('H915F>B9!E<A,40;5@%<B?+;
@r1144
CTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCCGCACGCTC
+
76<-%*"*F2)4/:#>C*?@55@F+>A'1*1H3<7;(;#5>,1E:8(#?*@)4?(H-$6F027,09
@r1145
CGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACA
+
-'2%$-/6"B$0A<0$2%H2!4!;E3!#:8<B!/!C421A36/4CD?F-3G&C</A$/#"&"B?5G'D;35*%1.3B9%"!70(E<4438>7+$A&):8#15;40'-:-.!
@r1146
ANTGTNGTCATGGACAGCACGGAACGGGTGAAGCGGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCNCTTTTTACCTGCGACATACTGTCCGTGCCGCTCTCTTCCCNCTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGNTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCC
+
!#*"&'#++)(!$"$!')"&!)$!&'+)'*%!$+*()())($*'$&)*%((!+%"'('))%")$%&)%")*#+)#*&$!&%&$+$"%'$)+!#(!'"+%&*!($%'"$#")%"#'"%"&+)('!$'"#&+!#&)!(!#"$("#*%+'!'"'"(&(%#++#'!)'!&'%#)&**''$#((+$(#*&(#%')'+""+%+&*$+'%!+#&$&)&(+*#)!*)'$!)+("+!)#)$!)"%$++"'#'*+"%)&"*#($#*)*&+&%)"&&#)")%*(!*#()"&#("!'()"*#&+))+&"!'+"#$#+"'(!!!!%&+*"+)'&(###&#'''+$+#(&+)%#$!*+!''+*&)+
@r1147
CCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCNTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCC
+
/FEH04?E;!$"08.52+!23=)#)2>/G-%(0;:H.'#?$B-9>!7:D<4<3:76E!(BH%;9A5'4C5=&1883.22%'F$B)/(#7DBA6E*C*$""-290HB9'B1C>2*?"0!:FB*%/<25#E!523$4G,G46B?#&BH+;(8+)H"..AB.'5-.42*%8:6:E>D+A*
@r1148
AGGNACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGANTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTAC
+
?+;B>2.>6"+"GCG@<''#';8E%/*GE1(/8:4;!=.8=(?=*G'&F-C$%$"9?1%B2=*:@=71F="!>/H7%2FA"G@&4CF<+/?81>;+:BH;&-*-4=<7*>*@%8
@r1149
AGGAAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCNTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGNCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATACTAATATTAAAAA
+
(**#$+&'("*)&')$%$#&%(()*!#"!))&(##))+&**+("(%$$##)")&*'*!**!"$$!()*(*!&%##')&+#!('"&&#$))&())")('!$'*(+#*%'!!*)$+)+$)*"$#'&*"(*('*+'"&%!"'+$*'+&##)'%!!'''))*''"$!$%())&(&*%%(&%*'%)'('*))%*
@r1150
GCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGNCTGGTCAGAGGANTCGCCAGAATTCTCTGACGAATACTCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTANCCCTAATCGTCGTTTTAGGGGATTTTNCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGA
+
13&EB#H;%*17"8(?*C=:?;--6G&01H#C=0->=E;0.037;H4-G&2/26)'>=B?,9%H&(18@*?-:4*A.2EA+%?95>905<@5/:!FF@(B0F3G0.%@>?F(":3G29D5"F5;G(/9+!#"&;+:.7+B8*92C23"<F!-5;BD;5C72-::'6?(F??:68?++B9"*?>&.;-=?9D%8.A'!(-78D1A:!)#H8$/C2C*&11%C57"71=98F%:<A
@r1151
ANATTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCNATTT
+
)!'+*))&('&$+()!")++#*%)+)$)+&&(!+"#*(*(*&($!#!*)'$)*
@r1152
TTGTTGTGTCGCTGCAGCATTCGNTTCCGACGTTTTCGCCGCANCGGCACTGGTGGCCCCCGCGTTTTTTGA
+
++"(!'''*$%+('(""$+(#*%%*#&+#'$'('+'!('"+!#$%!*$)'&*$+)+'))$&*'*()))')$"
@r1153
ANTNACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCG
+
'""!+(&)%)$#)*++&")"$#"$+''*(%%'$$*'+)+("
@r1154
GGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATANTTCCTGCCTTCATTAAGGGC
+
F07B2DG4+510;,>')8C=AF;0)GG;&;H;,$#%(6'2("/;?%&89+'-4-'1?629(C+D/'&)A&%7"4H$5F7/41"%#!;15H#!*9C+C
@r1155
ATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCNCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACAGTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTC
+
*G4#;(&9AA8G$;G.9..:(&EC82BB,H;6,"5)FF(CCF:8$+,$:?9!%%8&;4$!*,/3E:934"**-0D&6<.=E>?)EB87,>6$F<F%B971"AD9-'&:@&+.$,"!4;"<EB;-4$9=G@!-9=+,#%;5@=0.5&B,8G)DB2+*<AF2HH?0*7!=GA*)-5)*1E+?F-C<@1C4;C()461*>CA:*-%&=)C$!+6-&%>:0CB#1A'9$%?$9?)BG906=$F9D("%.H)*%@9>0-#:%<9$""#,:+2486!A&'0.G7$,*+"G!3F$2E0-"?GB!B?D4$;1@7.8&#4''4(E+@%+9B$":#511%=:">?>'B-%$*!D4-@"#!$$3:G;--<<55@=&"B.-%"5.-CCC7G=!954>GB?-??/:"B6%.()8-A/@E,.1D24;@;0-,AG1.2?&7>$
@r1156
GATACCGCACTTCCCGCAGCCTCTGTAGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTT
+
;,G+3G&F?=G#(.>(7%F*?C<E8#)4#).7D"'*<83@63=&''&H"<)=*-00G*4A3>)<@C1$=A
@r1157
CGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTC
+
)'#3,!585'+=6G!<-*:)B<'3!>4<67FC'.0%6-*9$B0.H6.$
@r1158
NTTACCCATCACCANCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGANCCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGNTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTGGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCNTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCANCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTC
+
!63<9:?@H2*#H#84'2;8F&#D?1".HG;4<+>1@:1A0C!=3G6@E?-F!,!8%'?,G4-2.!":+71*=A5>"18(&?<.>F2>";<=-1=',@9$$947?E=1BG&;#E;,/7+&,3<!.A4H$H(&)+A&>D7:*3&C%8-H6>7<<37D?D6D+:9*8ED0(ED5<(E')%$466?''<:1,,>E=0G<#B7'G&:)=HE?8"8(,C&'';D">42$?#:3/6G15D2'@2G2""0E%F5==3CD/2A$D-:+H(0!2D,89F'*11;2&G.+A1=?64)*!9$9#<'E-*BH!8*H:BH#29A.8-*0>/$474!/#>=-B1;45,DA&F@$FC4*?2#9H/'6HF
@r1159
ACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGA
+
+;2?*0"35,2BA5'7$2-<658%<>"H9*,01"C(<GA%C&0./G*-D'!-6E<!"D$0?!<,A1D-7?BH!@/7&'?;C1H;955%D)2+<3A#2"E$G6*!<9")B,&EF?>$G0(7%+5*>&-7$C9:*%8:44(E+?%#H$'H">6)C1)&F6'E)@<A0-C+%,@0G/53,#&>!2-H<A*&H7?:B<9=+'$@F$*>,-G3.=@B/F-74$'"C=@#@4/;H<!6E=8"(9B<,
@r1160
CGCNTGTTNTAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGCTACGTCGAAGT
+
!&&&)'&'#+)('')*$#%%'((!#+$!*"!#"&)'#"#($$(#&&**("$*&"%#!*
@r1161
GGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACC
+
=?.#($)=GH$"E$-'5D3"C$9CD#6A;;=A?E'D!)//&GF"G<-
@r1162
NNCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAA
+
"&-9G7%28,,:',7G%#3GE9;:;;23F#77F@3*)#2FAG72F7(G131'>?6@@"7.*H$C3C>5.A:<.->9.EE&,:#7?3'>G%;/"%+4*7=/"B%1';&G!6,$6D7BH3;#/?1*?B?,*H3?@':#7<(:E&>%(0'-+:6:)E1A='(=F#4:5G!/,@!@25*);*
@r1163
TNTANCGGGGAATGATANTGCNNGANACNNTACCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTC
+
""%$"&!!(%!"#%()'%)'%%'&))#)!#%$'*++*+*$%'((&!$"&($'+&%('!#(%'!'++
@r1164
GTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGNGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTAC
+
=H;&E;GH.!H,H>67/+@02H20=$;;$B4E%6604G1-#6(&<#D'#HE4B*%?-2C&#"B.:*7@6D6B;%E73->#78C+H*@+H7HC8$>$0DD"7$<73400
@r1165
CAATGCAGGATATTCCCANCTCCGGTNAAGGATGGAAGAGAGTA
+
!);.)0C':DF6/490"1"##$B:.0B<#*&E%F)29-*65($&
@r1166
NNTAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCNTACCGTATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAA
+
"#6*6##:7;70B#F9H5(#(4A1'14GBE-GA&"@=.>-?>+<4:%5?3E(3<>?D)>:;0563+*()@@4*A4!4/9:?(/!+&.F29F>?57F;;D=7?./?"2G7:B1EF.8".+&@4:&#2!
@r1167
AGNCCCGTCCCCTCCAGATTATCCANATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGA
+
"*!#(&)'&#+'%*+#&*)&"*&)$)#'+$""$+"+&&)!)*%#'!"'#"+)!!#&%&)*!'"'&"*!')*&)%!&(*%(%&(&!$&"*&'&"'!+*+$'+'**#%"+#+$#$*#$#$*)'&")'("+'))'("&)"((+#&*&!"!!"'$##!$(*()*+*
@r1168
AATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCA
+
3=*#-E.7F,*-='-/2HH7,5$2&)=E"G18+/#38+;C(3D:8)3+""!AB8=F-$8HG0<3/0E401>B=-$<;EG1.:C58(0"!F8)HA'HGD.AE-8;2>47(+1/)F699&HD,%5A,&!:((G-$-B>@E;*06$!..49(?=/#":D)D?"$)2GB*6EEG(""EA6-.-@'7#9H2'G@G-7
@r1169
CNNAGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCNTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTA
+
*"#"(*+*)$')"#+*%((+)#$*"#&%!!!)+!&"*+'(+!'#!'$)'$(%"(#$)"$(*%)(""((&'"')!++('&$%#!!!"#"'##**&!()(++($$)*$&$$"&$!#+')$$)&+)*
@r1170
CATAAGCGCCTACATGATACNCACTATCGCCATCGGCATTGCCTC
+
%CDG5836=2E2*$>3"8A/,A7D(CBC+)@<>8*@5B59:7C+:
@r1171
GAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAANATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGC
+
<H=#.<80E4,*5#58*HHC>D'5G5-'E$;2DG),06?D'>!.,,-)-"@,&2'D.8C0$!.A:#D;D,.7.4DH)BE$<"A2HEB"&A"*71..5,EFFF6;"%)71E#!>'A!DG!G*:)-#33*(6H3,9G:4H>'F:!!&"$*8#&.7>G<"HG1?<D9B?3E=*,
@r1172
AGTATCTGCATATTATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAG
+
@D2H+49$5ECA2>%'@4.EC.1A4"8>G*&(8G+'"B=7>,B#%":,&.C
@r1173
TACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAA
+
$B+B;=9D;-<#,+/3$F%@(?@"FA;,)(2$8!G<6(1-2*
@r1174
TGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCC
+
H/H?A(#FE)#.)*$G'&&8%*4*H/5';F3A!+9!:=@7GFB6.G.%565/%%?+:G#%B3"D?5/AE2(?":A27.$!B?5-D4E@($>"@62#%&>
@r1175
CTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTNCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGAATCCAGATGTCGTCTGCTTTCTT
+
%21,88A2';"$-A6#7A?<4)F-.C#H,#-74H*,@9:3"*9;H.%D?'&(?+04:%C2GG(4(1-5H.HG#C$$B'82DF5)46E)&"3@,48)GF*#88@8?,94)"=G-F57,)2E"4=;-<#3,&33D2+7/->G8C18A5*%C%-,!D*>,2.9+6
@r1176
NGNATATNGNGNANAAAAGAANTTANTNCNNAANNGGTGTNNCNTTTNNGCATTNTTNANNCNGNNGNTNNNANNNTAGCCNCNGTA
+
"##"$"##$$$!$#""$!$"$!$$#"#$$#!"#"!$$$#$!!""$#!$"#$!"!!!##$#!!"#!!$"#!$"$!!#$!!$$!"##""
@r1177
AGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCA
+
$&1='?%A-C!1,9F5<H'7ACF7,*%$*"5+)A@D609$GC/4E.G%23*("DA<6(;?4&*FF'.;1B?)@H<?3H+946G,H3>(6<C5+(G5>A('E#@-.21A<)+G%F0+$=0$A98>4@()2@&=:/E9C:077!EB'"5+>0+&D":BC2B%B5'4G2&1C"!.D+E9D3HAH)2"1<GD0"3C:@674EA<B?7B,6D!9@29<*,=1"++7=2-4D1*?B=.0@.+,=#82@=+%/D06:!G!<)'F7H:$#?H1"2%":EH>BD(DF2>.H
@r1178
CATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACTCCAAAGCCTTCTGCTTTGAATACTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTNCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATT
+
=FGB:E4'0'>HAGGD5=;0#:.>AB"G-A$#**%A3DCB5-1+;/*##G/(%"&&=&5D3C4BD!09C1(E>"3%G7?'H+5,4>@777F:C<-'9A*7B2@+A4-)5(8+E:-)F2%47D25&H=284)(*,DC"1G*0C".@0&C+>54C%?;*DC?14HF+6&@G-40;AE$EH,&.<,5(''=>#-1D)H'0-62E($H<3)<:/''@..A--8HF+(8D7:-<).=?-GAH.HG9;BB-?(C)$22E/::F<D575)07BB.9D53D/D#D&:B/AA!*9
@r1179
TAATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTT
+
""%$*'*+'(&%+$!(*+++)!%!'+)'"+()#++"('$%+%)*$())""+&+%(&(')!$+('"+"!"**(
@r1180
AAACCGATATGTCATTGGATGTTCNCAACCTGTATCCATGAAAACGTAATGCACGTCTTTACATGCCCGTCGCTTTTGCTCCATTAGT
+
:8!3:E38-6$()G-B<8+-''6AE:)@E&$9>4'##'=!>!D?%:G%?0G$+E,&%++/3"*82-./0#1-''-;DA+G297"A(C:
@r1181
ANAATTNNCNNTAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTGGTCTTTGCTCTTGCATTTTCGCTAGNAATTAATGTGCATCCATTAT
+
&'))#*!$&#$&"$+"$($!*&)++'%&$$)'!*#(#(*"!('"!'#$"((*&*+*$)#)%))''&$+$')*!#+$!#)!'+*#)$+$'(#!(+"&!"&))&)!$
@r1182
GGCCAGAATNCAATAACGGNAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACG
+
.&5;368;;<88*79):C0/@DDD);6%.C/!CCG6+,@%"16F8():9-81./3=B#2#.:!9*,.,GH..:8:1:0<*B@).396=*'5#(+09#,?G=6
@r1183
TCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTC
+
=?&<H83#E('!2G>7G?589!/C5%AD?%5D?G21#:;/0;%5E'-4A'!-9,;653(!736207&57>:31*"'"HE<C8*(0-(D3>A;EA-.D7?FG-"")*&(/$<
@r1184
TGAAGAGGATCAGAAATGGGANGAAGGCGAAGTCATGAGCGCCGGG
+
@)!?=+G6=G=(#28/!84>%9B/-%C8;64+1.D4F6%?(E/>D!
@r1185
TGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGG
+
44>CB/=?<D*#DHH@*+4<>=%:&;2*AB;+4%1#>80G:F@<>(EG#F#/!=!3=#(.:?;>54*08EA,>8$<%&(4EAE&,#>-+'6!B%'6*H*(7%C>CG-6@/
@r1186
TCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTG
+
;%F=?#5,(4%$(G>6$G<9#.'B-*3@%&3?5G!/6&50H6869G/>1*9B#/G-0++,#,HB6@&A2?7'1H0!H-01-=474F8
@r1187
NCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGT
+
$.>D@4'CC='9@/'!9C-')92/2(F;4&"$>2E3(HA'=1;'".="B5H$2)!6F3CE>/504,"8?(#8C1$?'7,460921+@B,:'?<F/D
@r1188
ATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATNTCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGNGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTNGAATTNCTGATCGCACTTTATCGTTTTGCATCTTAATGCGTT
+
2%FD+D?@:G/=H1A*2A!AE3'E,)E!F-&7D/$:%")E8094;5BD&"3&<67F(5&#<<&++"5">=,2&9,%,5//H%.7?<DC'%"<&&"5FD,@;6<G@A:$,CD"@-E*B-&&?A,4'=5F==B%(+/?/'/AE%/.#20-03-36@<(</18870>C#.':/EH#E,"4=#B5E$<=C1?BC$27<'/?%AA&+="2:(D,2=3ED9B),-8!(.;E:G$1!-"-0F?)G/%1G4#A""7+4*9+:DE0
@r1189
AATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGATTAATTATGCGGAACAGAATC
+
?'DH20)5$1;60!4$1;E.(%8D<CG07><"(%C;'BF=1%."!F-C%0#$'7G.(4D5'=305$??
@r1190
TCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGANTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAANTGCGCCGCNTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCG
+
B4B5<)8C3.?*)(/7:8(59"(&:>@D0'$7H"E$99>-0"!E@@:8:%%'D0(G>A3C;=D2!F=%D0>HH,#CG!1D9,.>'C!E56!19)%?C>?#'>0<2?)CE5!!@+*@2-+;#G)08:4-?)B3;:E6<,H?@=8<"E1F&='68$F2&G"===$'>.&+$C:1@378<>A!1'C6%/@'<*9&41$!A5,<7&02?#B3"-7>;<#<0'+!DH)@C3EHA*-4)9+(/B9;+69"(!!$&B&#C1)@/$'9H/C(
@r1191
GGCTATGATACTCGTTCTTAACTCAACGGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCNTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCG
+
236.(0%24/,&1D)H.)04A2"2E=.>4F)#:+B=*DB?:?,2<1;-H!>BC,((&!!,9.:%0;(49<2,=08-;>@B'H05:*6=18#$C-G!C$"@BGC@GD,8!%F&5&G,B31-8!!<,.3D./>;0A./5=@$-/#B="2)1=7,":-/(G%<2E55H>0#
@r1192
NATCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCNGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTT
+
!"!,&;GD(,A<,$:*14("=AE0#G555<?4/.</8G+:0=#/A4A()<08=7#($A8H34-)A-$$90,BH"$(-+C@(64E="?,@=$-?2>7!H=*250@>,4'*%9;
@r1193
ACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCA
+
/8?&9@+@7AB%@5*G/C)F3#E.:H3=A!:<G<1.-G771</,:#;$H=>?3&C3<G3D<>89H,?8E*/HB!?
@r1194
GGGACGAAAACCACATCGTCGTTNGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAA
+
9'7:FF809905+'0G)??,&G4/G3/=F)%,A(5HBB(!5?.722,/E;.$E"8"/2;$+<9B'A?B8#*:#+B"E.F.
@r1195
GGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCC
+
32,0@34F1?2&=(C'6!5*5#?"#.!:=">-A!=00)*H*.D/D<9E)&2/'6:2$98C*&3.9&$>71<@29H@.)=27D)64A!3
@r1196
GCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATT
+
DB(("81$C#0/9A=887:'BB$#,%39<)*(56G1'A$.,(<
@r1197
TGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGNGGGAGCCCGTCGAGAATACTGGCAATTTCAC
+
C>9&'76@HF2+GHH/D+:*4>H4:19'"@H$>)!30:9$G1=1HG5/'"<%A2<%3,/1);.7$5$52$D9C/,<3G-(%@;?704=?>621414DB3
@r1198
TCTGGGCATCGNGGAGGAAGAAGCCAGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAA
+
G-B*$*.<->G7<(,F1/<>;=-E7(A1<*.A)+!%H-8$?-=E%9:F75,0.3H5;03!
@r1199
CTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACCCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGTTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACNGCTCAAACACGGAGTAGCCGTTATCCGTATCCT
+
6/D+/#3@GG;GAF;*B42F4&@7>(+H*D?!#3-!$E2$0?:*4;.GE$7D#H'HB0GD&/EA/BC#D<.*>$!'B57,0AF+'#3;2"6C(D466#*@(:!>1.<%"H(A*0=><3:"6C*!<4C>2,9A="<G!.?6E.ED%=-,!;"%#CC1@1;+/:<!)>+;)>01A&<'?;D9>=G>?*F:
@r1200
GACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCCGCATGACTGCCACAGATGGCATATTAACGNCA
+
+?GH'+9,/$1+A?:1+$>!12#H6?),$8!8C#+46)D=:)7-D2/D!-G4@?<FA.H'.!B89G$F-/8B"22(13)!DG8:D?*.71E8"*'.@@#E(@8G47
@r1201
GGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCA
+
$)F+943#?+6H&0/<!>B7F%*#532@0/A.>-79!=:#@$
@r1202
GCGGTATCAGCATCGCAGAGCAAANGTGCGGCNGAATCGGCGACAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACA
+
:C":=08%!)@<43;G"4FA#@$>&$,#'C(84A@'3C8=D55F>@"4)D)'48E70!3"E=*@2FH1%75%5H3!>8$?"06(???B-A649)E2,GD&-)#..>B:B&)/*F.GD
@r1203
AAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCANTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAG
+
0G(/B@?$:%%2@5:D(;&)G?'1FA+-@#0:,C=>12CB3D('.%A)1$,;5G;"F.2*.!D-1G4:/H+14!>#/&=CFB2(&FG;>3@5910*28,2=0=A2%CD@3?+#H!A+188@:(%%(B9A%H<,(#G8A9$5(=>72F.,F+07FA&(0)E;</+"#,@6=3:31/=;G+H(=/,:1(FHH:C&F%A9;$>/1:.?&6<8G'
@r1204
AGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAANTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGG
+
4*,):,>@13C3*/%%#'6D3F,%?C9$E<?)@4769A@)93)%%'9+F.:=<6&%E$+!8(*FDG3E0%$;=,(4$96&(C410,('.54DH+23(8E!*$4B
@r1205
TATGTTGCTCAGTTGCAGCGTTCNGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGA
+
7-'E;@A2%1$1!3;873.!633"#'<=8<"<;G5A=*G>48@76E(0=63?7GC?(43
@r1206
CACGCCTGCCTGTTGCTTGTTACGGTTGATTTCTAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTC
+
-(0DF:6!992'1(;E,$@"*;C+@198"<A./E9<.05-&DD"C"%<.-/$0,8@FB@5")>(02,<(1;3/&>&'%5@E%$((DC(1-8><!'C<B,-FCDC3A>.<3GD8F)4D@1*CC7'=<B7*?B4A@4D&)EE-=2&G1!
@r1207
NNGNNTGCTNNNATCCANTNGATGCCNGNNTNNNTGNATANNCATTNTGNNNTGGCCNNCNNNNNTTCNGNCGGGNNATNATTNANNGACNGNNANNNNNNNNCCGGGCNNNNTNNNAANCTNTTNNNNNTN
+
"!!!$$#"""!!!#""!#$#"$"$##$$"!!!"!!#"##"!!!$#$$""$!$!####$"#!#"#!$$$!#!$#!!$!""!#""!"#!"$$"#!##"$"!#"!!#"$""$#""!"!!!!"!###"$!"#$""!
@r1208
GGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCG
+
3F020:/=2<%5'34;&CH4#$&F(4,*"91(E,2?.C+).".A+(@=<<$C.09;F>+F&/,<17?+6<6B+/FD*!;4C=%F8#;F(;
@r1209
TTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGC
+
&%+$)"*&"!#(&&)%+)*!)*##!#&'&'*%"+$($!"'!
@r1210
GCCCCCATCCCCATACGCGCATTTCNTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACNCGGTCAG
+
@%0G-.#&;.G#.9&A&(F@<7CB7H*)F93#0-D?;GA8DG00"7E@4//6(1"</G9&&G&.-<;';26EE?GC%7
@r1211
CTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGAC
+
89;$44#<&4>32DG<,!$F58,"6)0H+A#:7%/#G)C5FH>-?,4
@r1212
CGGGGACGANNGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGNCAGGACACCCCTCTCAGCCGGG
+
FB7/H/<2:D4(4B1;9A-/:%(120(@44%.**:++4G;>DD0:78('A&E#CD@&-;.(F;?%;.)G;>8=F<=CG3D7';+F51AD&>9?/.A818
@r1213
TAGGATTAGAAGGTCGAACCGNTTTAAAAGCGATGATAATGAACAGAGATAAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAAT
+
ED$*+AF?42)=(1!H64*'3D3!)$("/,</9+%"%$,/(1C&C@3*E","E9-G1'95A,.@G6E!G-A(%/5+)7?@=E,G;$/#D;;,)1!8(5&70CA)7E8A558+0$+;#A.GE@F4GA#A2&7*B@)2)A%D(%@(;F;)A@)%>'
@r1214
GTTACTAACGGGTCTTGTTCGATTAACNGNCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTNATAACAGGAGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTAAGCAATACGCTTACTNCCATCCGAGATAACACCNTCGTAATACTCACGCTG
+
+$"%$))&+*#)""""("*)'%"%*%'*'('#')+"'()'#($*+!))$"(&+$($'!+!*%&*#'+&()#*$'()$("'#!"(++*!#$#""++!$)'%"*&%#%"(+)'&*""+$!$'*&$!*+%"&'(+&*#))%&("($!+$$+%&)+!(#&(!(""'!&%&'#%$&%*&*!&#!!$")(+$&'%&)+$
@r1215
AGATTGCGAACACCGCTTTTGTACTGGCCGNGATTGCAGATGTT
+
5$&G3-HB+'E5C":$!5.'D?+CD0.>,"%1B<)4&/1*1@"F
@r1216
AGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCT
+
,($/#>F+1?+1/;=%%,/?H(,.;"$%;:*3C$;4)36A1
@r1217
CACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCG
+
!E@"+%57/*>?A9((1C<F4)-)7@/),A8+:E?(<G.GC(10@%@F7950+F6:
@r1218
TTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCANTCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTG
+
+#1!E350@&03C<E88+A2*!&4*G,:D?@4?7F=#--$&1=G0=*C7G:3(CB2$?+!67#->*;',&<GD"@**;:*3+G-H(B?10HH?=GG#D&"D?52H!-A>*<+!19C
@r1219
AAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCNGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAAGATTAAGTTANGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGNCCCTGAT
+
@G9D%9"!6<@.,..#7/"2.4%$0:'!*D6=$)A;F!F734E?)F(74(#,>#(,7)/0*G-8C=47$82A?8'7=%B2=1/"@>-?-%7172>EH)$B<")><">:"-4%6;D1-2?9BA/G990C191&F%7;>F'9C-07C-%,@41(0(;%B$4(CA4>.C?DACF9)7$@$-)$&8%#&#F9.$29(',6(->."4-1($1G92,G+2=DF+/(=:%(*09#+157-40*=5%77B'+@$(("#"9?)+B0#D$8.'6;/$>=%,
@r1220
CGTGGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCA
+
*G9<9/D:-D(,"*8'5)(C@,#D@%99<'-H78CC/1HC+'#9<6@>FF)?8,-B=C2G>!G17359&1#5-&/A
@r1221
GCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCA
+
?H=ECH)!H$2)-EG./70*0#?;6;:7,7877"C3)(+!)HB:?(3
@r1222
TNTNTNGANGANNAANNNGNNTNCGGANTNNCGTTANTGAACANNNANTCNANGGNNNACACANNCNGTGNNGACNTNNCANAANTNGGT
+
$"#!#$"#"!#!$!$$"#$#"$!$$#$$##$$$""!$$#!#"$!#!!$$""!!###"###$#!!#$"#!$"$$$$!#!!"$"!$!$!#!$
@r1223
TCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTG
+
)8-?"8-1#>5.$3C(5!.H!"D>&-G<'698A>8++H=6E4;!E<B"%B80#95C"-C'+C1&C6&=5;9"!8GF5/8?&)6:E
@r1224
ACATTACGCATCGTTCACCTCTCACTGTTTTAGAATAAAACGCCCGTTCCCGGACGAACCTCTGTNACACACTCAGACCACGC
+
,'7<A!:FG2D*D%<=&E</,,>*.BB#EF8*<F&.:B!BA====!C#H3;49-F(C74(?D60">3E;#0$((G.<"0AG35
@r1225
ACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTNATTCTTCTATTTCTGATGCTGAAT
+
G>1)<?B$-7<'>9885+D5!83*F'(/&0752D(;>1/1,1),-FF"A=";9:>;!;9:,6<!)A.8-1#9!>87:';<7/?>"GC>7B"+;)*F4<C6?/$#63+B@8+$H*+A>/:,5H)%+85E>E=
@r1226
TNTCNATGNTAACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAANACTGAG
+
'!$(""*("!!+#*""#"$+#"$!*++%*$%!!#%$*%%&)(+$%%%$**()*&**(!$$!+#
@r1227
AAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGAT
+
>2A1$'FGH1B'(*.(3">H>6)"B57'?@$<2%?").#%,,4A(6==%-&-&/-6@&::)0$.>G4=*"'89,EDF":*77)#$B3'<$;67)AE4'A6:<="7'>'4/HH82:>4<
@r1228
CCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTTTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAAATTTCAT
+
)-G":?+8C$!)A)2!A'0@"C"#.;4-,@A9/56&-/")04E>@9E0A@)F*&38"?9F4=!91?+6EB=(,+&((!428<56(?C,7AE9+/&%>;+,<*"0C)%A#.7A@;!$#G%$=6<F=8DB#50E,&EB9E;EB077<B2G&&HD
@r1229
AGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACC
+
2')9CCD%1:1<$-1*:4>;)"5E1@AF';%*BD%$>A+.
@r1230
CGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGT
+
$&&++%$$&&%$+(%'")'(")(+"$**%+$*$#!%)&*"!*'&#('*+*
@r1231
CGTGGCCTTCCAGACGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGTCCATCAC
+
5<"/E7$'!@90C,#0+>$4C.*&>;)8"%@%444)C&<H97F2>=,78:$@1%G2@E)#?.0&+4E(,E0,"C>%!7>>E"9=!A4'34C:*8E8E)2
@r1232
TGTTTTATTTACTATCACANGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTCATTCGA
+
+?D,"".;#.G=?(HE.C;)E<1.9+A:%4$D,H>1D.&B:E>%"FA/A9F&/"H4@%E:$8*
@r1233
AGGAGGTTCTGAAACTTATCAGTAAACAGAGAGGNTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGA
+
;3?.;<DB(74H0BF17C.CF5.*=*-H<F"./7A2<988>3A$4"@D17C(F/:)!8!77;35<',*$D1</#@>C-#:$<#-;:8>F>16/-6D?G?'&?*D3F%(<&(/"0>=9,+?H"AH?1!@>;/*".12.'+-?9)0HED>?.H+'GHBB*DC#H+D8>+)
@r1234
GGTCACTGTTGCNCTGCGGCTGGTAAGGNATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCNTTACACTGGTGTGTTCAGCAAATCGTTAAAGNCATCAGATGCCGGGTTACCTGCA
+
0H5B?&&D#6#2*,=2;2,+H$=%/F;81(<6+B<$81->:<E!'(,BE)&-F9;#C<3CE:?;171!HGH*H$;8EB54<=&G@28)7GG)6H-9>96?"=<;ECC4C/(,,G+'51*1
@r1235
TAATGACATAAGNCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCAACGGATAAATCCGGGACTCCATCCACGCATCCAGCTNTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCNATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGNCGGTGAGATAAACGGCAACTGCCGGAANATCCGCCTCATCAAAAACAGCGGNGCGAC
+
D2AE%C)4(';#+42?=%%+H84?93>-.)/-/:!(1A#G+5)5H?F!D4")(9*)-<E::H@9FH)A(C(1<.19."07%$<4H8$91!9G>36=;=)<"!:#9!$B'-D?48"D-6+?&=6@+!5:=E#5&,*5*(4%;85;;0$*)).04;-:3":@G.=#!9C)2:$&?;?1D)-1);"56(CC0#6766>=H79(@4$G//45)@H3DB-3G2@;(C?$H2"9@8&%%-3.<H<G;;,!=#:)E9;-E=0'229"9,%5..B19'C-?*D;?9!3#A#!(9(,87+3A!7-'3=&"D(4CC
@r1236
NACCTTTNAAATTCGATCTGCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAANCAAACCAATCGTAGNAACCATTCAGGAANGCAACCG
+
!$95:"#@2>22B3*G0.#3F+3+A;G<'G>31G"C=%>G3,/8516F1E5F-E#G"F?@H73.B2!#3<G9?"'00D(.H%AH125F1245%!<F?2,2=+$.7D4G*:1
@r1237
GGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGG
+
'G#%HF)%,4@&B>A/B:+?4@945">"D:!1,F"-%?*H!=094//*9@
@r1238
CCNTGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCNGAATTATTTCTCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGAT
+
D$AH.EB)4!>=<C*<C>+<4%>/3/!0CH/>8>8C)'#4!10-=>@*/G'!B2!B+:(.*:">H83233%@((.G@(!6+D:+#8/41=.::7>?B*C0D=;E65E<0'F2&-<0&97%#00"B95F,8.!2-/>9.%1*1%=A<<A(D4D2>&C#=8=
@r1239
ATGAATNTCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCANTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTNTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGTCATTATTCA
+
&((#)&)(+)*&*#"+$%*$#)*$&*'*()&"%%+#!((#"&*!"))#&+")#+"+'&#&%&+&*++(*!+##&*!*##%%%$"''!!!%&$$+#)*$*+!'&&)*#)%'#!!&$%$)))%**+'**''")!*)"(&&!%!&+)+(%)#$)&"&'$")!(%%(#'(*%("+(*%##$)"**("!*%$&"&&(&&$+*&&&!%$'(!)#'+($!#()%+*'%++'!+&+%*!*&!$(!#&"(('##$(!%*%##$&&#)(($"'(+''$'!)+)")'(
@r1240
TTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATANACCANAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGC
+
:E*0..0+"B/1G'#7'+9G?(;9F3!F=07&FB%+C<F%47"@$&A0-:/38@H2).E*-D55&5AFFG*.?'.$.2*=0**"(
@r1241
TCCCACACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGATTTAAGGCGAGTTTTCGAATCTAAAGTTTATCTTTCTGTTTCTGCTCCTCTC
+
&$E*@<:E.0$55,48+7&1B/G>=:G"8,#=E$#CC69?01%@.8,'$(?65H!!19%)'FG"+9'8$4<F4$?>/(-F@07DG>&?@<'>2&>F9B93>:4.('@-;/!E;G1GC.-9/<4?D38H=BH5EB"B(,:??>H7
@r1242
GGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGNCTGAACGAACAGTTCACC
+
.8+?$;#4A*4(2>+F(D-=G@?2'-03#-:%HA<$?@6A.C.(!.@G4767CG!A22;.#8F-:+E2C,8$?;$!B;9B?H;)+8?"?A=H."<"76;6G<2?1-3(:@7*$0&.<,C":<;*8
@r1243
CCGTCATCATCACCGGATAATGCCAGNGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGG
+
/,49$GF'7G<4<02><%$>$3?2%(:/H83'469:*<4!(7%C,9)6H6".574=11@#+B"E286;+;E!,(&9<&%A4?4DG=@H"5@F8C;'.GG*?F)2D"D0>BD$$!A,-7(;#)A>,,.:.D;!(1$FF,0>3A"""<1&2#1:
@r1244
TCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGT
+
,:.>!$F+0+"&*.%:&H5<809-3H@@7@0(&F65":D@$5D"@=1DC)$<#""?A1E@*6CFE'?#H<1!%-B,%';9#5$30F;=@B6-"C7
@r1245
TGNACGTTACGGNCGTAATGNTACGAAGATGGANGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACC
+
$&%!%)()$*%)+'+#)*!'%!"!)("+$&#!&!%"#'%'$""#%*&'+!$)$(('*#'&"+&#)&(&
@r1246
NGANGCTTATCGGAANTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACNAAATCCGGTAGTAACTTGCTAA
+
(&*'&$!+)!%++(+"($+''%!()!&"$'&+&'!)$""&&*''&%$#"'&#$*)*$&*)!!!%(*++&!%%*(%(#
@r1247
ACTGCCCGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGNAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCNCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCAC
+
(+$#)'$)&))')!&$%#&&+$$+*%*%+"++"!!$%!%"*$'($*#*+#)***%#&%*+'(*)+%#"'("+')%&+"#"%&"%$"&'%(!%+"#++*%$'+*'$"'!+#(!##&*$'#$#'(('""+'%++$+$!$%""!!#'!*#%%#($$*'%"'('+%%%+#'%"("*$&&#!$$#&!#($(*%'+"$)#%#(+*'$'+)()+#%!*#"%(&&%)'"(&+)!*$"$%%*+%+*&&&&($!"!$
@r1248
TGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATNAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCATTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAAT
+
>8)1:35H.)CC,*E5?&2*%C:H)&=87G&*#.BC%B+7'0.H13:.(3879E(!<,E8>A%8-@EC6D6=5>)&B,1"?0/99-H.?>?"&970C:3$#B$;.!?(71D.)GF*',!(8*%1*827:5F9!G6,G3E512<,1881<-'=G$.</?4$:*"<+H/A!4:8
@r1249
AGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTNGTCTGACCACTTAACGC
+
6(F'/2);<H!C>9&*>='4@<)4+A-G#*$>7H1":,8F'200??%AD0#6?).9%C9@G*)15
@r1250
ATCTGAACCAGCAGGCGGACTTCCCACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGG
+
$$"+):;,-*'GC.$;/3>%2=5:5B0$<(54%6#"-$<"B0"7)",'%EFE74!?$8%6/;/F,6@30H*%">B+##0?02(6*5B?4:5BD
@r1251
CCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCNTT
+
0,*D16E4&F9'H%1GA!70E375@C&C*4!'@12.6=-(58/(0,1"2=2()+0:;<F6;*,>F2FCB17D&336>$?.'1,
@r1252
NCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCG
+
)&C5G964,34.$AC+A6"#8-<E,C83/:-00%'#611($/+A#&49
@r1253
TTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGG
+
G@>,=C1:?:4&7,CF('H?$1(:8<36!,&7-"CA@/*/=?G@'D@('="F""><!.%1D3%6/+#
@r1254
GAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGC
+
471'#5;>3;#<:%C)("$7&)-;>%8=;(<$B;<;!/?"!%+5B9@"C7D97"/G+)3=.@'/)>5H:-D4<:<1C/:7972?H9!G
@r1255
ACAGGGACATCGCCACCAGTAACGCGCCGGTTCTGGTGATCGCGNCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTT
+
81-3)'E'9G.?!+8G2'$@G=7A@6?F2"H7H9)=CB*!9)?47H@,==*%.5%A934H>F2-5+#(=%)('51$0-2*+=#/-!;
@r1256
CATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACG
+
90F&<&3B441-@9#;&/=<?1?"F-=F6,&!:%HG"(!5!//>6!.@1<D"@2#.G*C"27*65@8"23?),>0#F046'.?+-H4'E45.,9AB30/GG1>;,@)H6CDD'
@r1257
CTTCAGACGTGCNGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTT
+
1*>*C>;?+'%;;3368/B$B$21+07:9&#*<"4C)+!?"20@*(A
@r1258
NNAACTCTTTCCATNCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCAGATGCCCAGATAG
+
"#+&+'!($&$!!$**"*&(!(&%&"#&$)""++%+#*+"%%$)#))(%"#'$"*#*("!+#&%+$+)&#'
@r1259
GAAATGCGCGTNTGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCG
+
%&*(+)#))&**(!%)')($'#(#*!(*'+$+&(*"+%"'$#"&)$%#((#)'
@r1260
ATCCGGCACCTGAGCAGNCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGNATCGCTGTCC
+
B$$D?F*.=E<"';#%+12H55CA!#<&HD?H5FA8:6="-/#0&0(4G*@.#%$&%$B,+28$
@r1261
TTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGT
+
1&?<</&311F2)4>#%H/9.%8@$#@G(9/0A*H?1-"D6F0<G$-,!)$+<C;-+HC$C8>A"*/HBC+9-E23:A4+:/629#.#*=)76(?,BD(6>13+'869=G"?+75AF@,(*=D%$&3
@r1262
GCGCCAGCATGATTAATACAGCATTTAATACAGAGNCGTGTTTATTGAGTCG
+
H*,#19,@+=6-(0DCAD/A5B#'>-&?F,:D:=4AH!-#E;?E.@?!"8D/
@r1263
CAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGA
+
)B%HC:@&#6C0*$C@$,E).0=D5>E5:#81;BG:#5@<4;7+:B;3/48&8;C1'D'+GF4GC03%,DBG1.82E.!=?94A,3(/83#5*GHC"7218'7CD8E&!>D8#(>&"09-1F.+.#1;F-CD
@r1264
GATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACAC
+
$AG1D,%-05)*%38()5>F4#+6+9@57:'>?%7C'GA/6@#EB@0CHCD>07.:
@r1265
GCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCCCGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCT
+
)G+#4+4+//706B-B355';%;G>:"D>B>#0D4HHD-;7G69=/@&54#8%*)G7B=/2(9>H9B+1:@49&7):0-3'B*%DA@H$*C:>EF(E(<7&02;#@8?*1)*%>'<).DD+(2+-%0"0G'-#"6G
@r1266
TTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTNGGCTGC
+
G)0.<!GG531$#"'F0#5C$*FF#1>E1&!F<B23E58><F*>,*:2=#GBG5H
@r1267
GTCACCGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTG
+
&A??<#.E,=7>,3)?A$9+2C.2F?$:D$;97@E"#/(/;1F%>*#+,::BC&"!>6!7H.F1<#)6G;2,0#((.CC6%3+7>8+-(C
@r1268
GTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTA
+
,,6'66(1!A=2!9&7C&DG=E&-G11EH7!()?AB8@A')%8G&C>+<H
@r1269
GCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTG
+
=!.7B4?858A.'/;8!3!?<#EB/C9#2@/2A<>'/--=3(@:)9##7=9;B4%81:!F2:82#=('F83.7G.6#H<?-1%F!H$.FE+7?G@-==/-@)%!@9<?='$4@8C#<='(-+#265E8*(+2@6265B.6,,9/4:'24=$E2
@r1270
CAANCGCAAGGATTGCCCCGATGCCTTGTTCCTTTGNCGCGAGAATGGCGGCCANCAGGTCATGTTTTTCTGGCATGTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGC
+
*$("$+)'&!("$!#+""&"*%%")*#+$!*!"#*!%&"!$$"&()#*$"##&'($(%!+%)+"'"('*)"+()())(+%*(#!#&'%#'$+'+#)$*")+'#*!$&*&'%!##$#"%"""$%'!+#&&*!!+)&&!(+'''$'$#$%"#$()''#
@r1271
GCCGATCCGGAGCAGGAGGTGATCAGCCGCTAGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGNATCATGGG
+
8=C.<0'@BE)9@G(5$9,%+'-/#4G0E@"'9#H7&=+-A4<H2*6=910"C=D9+6!#.)-1'H/A8;:D2!13EGH!F03;$&F&9(!',6-(H1&:.=#<3A2F',E"C3G3;=<""!!F**6$3@,*H<
@r1272
ATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGTACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCNCTGAAT
+
:F.;A4G?9%8'.*(.?81"A4@;*8+:'B@,B'>E)!*>#9>#3=2F?+6/BG'!5/AB;(2<+34;0H:?+A0;5"!5!F4;C+4'<')$$<E%&B
@r1273
TNTCAGGTCAGACACGCAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCGGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATC
+
((2?E?9$E:3635A$@<(4!5=B41)H=AD@%E1G2/@B96&=&,A4"DCB&0"2=C$7-E(;;*D/C%AAAD$73&2&<$@0,D(#7=H8:+F54FA,E.5?3//.3(8+F@&F/<#$$-E@/875EB$B7%%G>&!>/?"<-:G;:+)H.?*.%,29(3:!/
@r1274
AATCCATGTGGGATGNGGTGCTGGATATTGGTCGTCATGATACCGCGCAGGAGATGCTGATTANGGCAGAGGCTGCGNATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCNGCCCGAAAGAAGGCTGAGCAGCAG
+
+"*$+(&)!'$$+(")%*%&'%$&%"("!(!")(+%#%*!&*+'$$"#'!$"+(%!"'"&'+!&#+!(('%+!(+$$$%(+'*"()$)&$'!("#)'"))'#$&$"'$%**(#$"(+'*(**&"!'(&&'(%$&)'"!)!$%)"$%#")*&%*$!!$+!)$!!"*#)%(&'('*$!!#+%++&*)###$)%$+#%#&'#$(+*#($)!*%+)*%"
@r1275
GCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTCATCAC
+
>)&;;;1D-;F63"0.A.*5+(:F8,F/:6/3464@DA6*2'(:G0/CF8-;"4BCB#52#$DB0?6'/67*=",;"=(;A8GCHC(
@r1276
GGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCNGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGG
+
7H9>%3EB';2.,E>E/C(3+(5?F,E-4D1835%/>.D9E93)>EED()>D;+76.<<1"EDG8.FA7F#A+$?F2<EHDBC/<0?9C4207=>13;7F
@r1277
ATATACTGGAATGTTTTAAAAGGCAGGTGNGCAAAATTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTNACATAGTAATAATTCCTTACGTTNTCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACANTGCTGGTGTTTCTTTTTCAGCTCA
+
,?'"#'"#-7<.-.<'9$!C*C@B%9$1'.32,89"9#(>/A"0:&AHG&12-7(!<'68=E/H;>(&.H:7:7$B)9C44*B1-=?.,/9%0:''2>AE%4F2D@>#+,&*+C+7G>AD56ED.&&1.>;F(<$*G2&H5H,#FC?5&5C$+#'A&B#-B=94'?5>G)#'='#
@r1278
ATAGAGAGTAACTTAAAAGAGAGATCNTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATNAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAANCTTCTTAAAGCT
+
*-E6$AB-B/&2=,2@6*0>,.>)38H@+8>?=81&-??=?/&+7B6*?,-:,+6(-8H(#9C;#2H=9+HCH9'DDCH>"%$/!92/&G&'>=B*@-<5(H54(8+@-*"@@)?*01-E<GCA6)=4</$;=)H259$24,H&3:A7@?<,=/==*@=4"G/?658&&(C,5):;)//%B:<$H07G%.1<6D$1&@GB";3EC.>G5E8@A&9:;&%5<'FE+4*';>9>95?8A14&/;2#65#?<D:*!*1F95E9$>::>C@+'#:%*<;==>-5"E,:?"3F(@6>-#5<770A)EH.B-D!H<@%A%;%?)$+6B),;26;6:686',D.F#5*%68G)8>-G4(#'&D?$*+:0-48?6E6<&)<G=E)D;A&))%;1F92F-H26/'.@@<;6H)-9'
@r1279
TGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGNCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGNC
+
E1G,2EE3(*AH",%.??3."%?0)8*5)>=B8G7'$E$$5$/'<."#%/8%"-2$(5->84.9-",7GA!GE338905676B;B>9#A)E:)1+.)9@+'.7,.*D'30019@@D&-/:83FB9G%=G3.;137C'C.*1('$66,+BE9!0F!/@"$'%::.8:
@r1280
CGAANTTCGGCGNACGTCCGGATGCTGAAGTGATGGCAGAGCGGAA
+
%)&#"")()*%#!')+"$()&(*&*#+%)('#%"!*&'$#%+%$!+
@r1281
TGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCT
+
2'/CH7>2GE2*?*)DF#>#-EB+9,@0;C8G6$180F7:/?&B.8->*HA)4.'3.<@67*'8G>6$8*49,CG'=+G:!3.-7$?+=5.7),BH#9.);$2:?62%')G
@r1282
GTCTGTGCACTCTGTGGTGNTGCGGCCAGAATGCGGCGGGCCGTTTT
+
A?8F2@2/F87$0?G3?,764C2D3&"!B-@A<)/@51C@36#/:FF
@r1283
CCANTCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTNGCTAAGACGTCGTGCGAGGAAAACAAGGTGANTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTGTAACGTGCGCTAACTGCNGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGT
+
$*(#(!(+!#(%))(+'(#++#'!$+''$*(*%*#&##&#!(#&%'#)!(#!&$(#+%$)%!&!*$%)"!"$*#'*&"(%)&(*!%*%"*%(!!*!"+('##("#!%&"%!!!$)*+%+*#&(*+%%'())&)(&#)($&%'%*(#$&"*')##()%'$'*&$!&%*$#(*$#%!"!$"++&$'&!**&+&)
@r1284
GACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGAT
+
.+@<.GB1;BB"3)+@)?&47H+!6#76"6<DF*>#1D/#&""110,@1G73&:3C""?>-#>1#FC
@r1285
TTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCT
+
+#!)+('!"$'!+'%')"#+%''$$!*+(&*!%&)!(+$&*('*&*%
@r1286
NCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGA
+
'+!$!!'+(&+(%"!+)+%()+#)&("#*%'&+(!%&)##(+$+*$#(*!+!))%$+"%!&'$%!#$'"%%&*&&$*&*%"'(!#(+
@r1287
AGCCTCTGCCTTAATCAGCATCTNCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATNCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGNTGCGGCCTCGTTCGCCGCC
+
")))++!''%$)!)+&&)'#%+"""(*($$$+*%!()$"!$#"($(+)#+"&+"&#+&+*!**!("**%(&#&)%))"+&&&+")""!#!&+($*)*((++#'(+&"(((+"%'!((!*)$#($$'!$)&(&+(#***&*%+*!&&$!%&%(*##!!+!)$#%)()*)$)&($++()!)%&
@r1288
CNAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCTGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGG
+
"+#%!'"'!$'*"'""!&$#("++"(#*%($**+!#$'#%()**''!%**!$('()*&'($%&$)&)"&'*'"""$#*!'*&"+%$''*(&++"+"%###($#!"%$!!)$%!#
@r1289
TTGNCCNCAGNCCCGACGTCGGGGCTGACGGCGATGGNTCGCCAGNTCCATAACGTGTCGGCGGAGCNGATTG
+
%)$"%*#%&#+)!)%'**#"!%#%#%$($($#$*$$%")*"!'#%&!(!%)$*&(#*&)*++%"+*+)**&#&
@r1290
CATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAAC
+
,A;#)C3/-7.!>#6B:EBH%G85+E)1!6)?%)-ED-*F4+/:F3AHF0;=B'9G(D74
@r1291
CTGTGTCCGGCACGCTGGTNAGCNGGACGCGGGCGCTNCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCANTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTG
+
$*)*(&+"+"!++""'#&!+"+#$&+""$#+*%#"'#+'##$*%&#%*%"&%**&"%)$!$!*($&)%%(+*'&!)*!!%""+##')'+*!(#((&&)'"*$%#$###+)#"++"%(!)%$%)$"+())+#"&*($"*+$&(*"(%$*'"''!'!(!&)($(""&#%
@r1292
GAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTG
+
44F34<9#H,1BE4FB$8>>?/GD#?<$GB"<9501""'1CA?H3B
@r1293
TGCAAGCNGANCCNNNNNNNNTNNNGGANNCAGAACTANT
+
""$"$#$##"#"$#"#"$!#!!!$"#""#!#$!$$$#$$$
@r1294
ATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTA
+
(GHC64>9!,*H..%)E&6<<5G1!?))&,<6D1"*'@%H'D$?/
@r1295
AANTGNNNANNCNTNCCANNNNTGANTTNAANGNNTGTANNAANNTNNCNNANAANCNANATNNTTNTCGNTCNNNNCNTNTGGANANTNGNNANTCNGNGACNGCNNCNNTAGNNCNNNAGNN
+
$!$#"#"""!""!#!#"$""!$#"##!$"$"$"!"#$#$!!$#$$!!!"!"$""$!"#!!"#"!#$"$"$!#"#$!!"!$#"$!$!!#""$""!!##"!$#$#!"$!""!!#$$!"""#!#$""
@r1296
AGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCGTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTNTACTGCCGGACCACCGACTGT
+
>)=/+)9CB35A+*7'&F&H57D-&<$<;#$;/+7'$'.@+/'6>01!3C;+02D.'1'56:B&!GC<&734'#:&#%."D+><<A<?1#9(7!>+231'%C$5$=CD<@D=#*%),=>*=)3FB2,12<?;/!A9<&(9>00":G"9E7';!-0&?D#-;0E-!:AF8DA"E>0D&2"1
@r1297
ATTCTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACT
+
3A.,1?H'7A+=7GH6#31;).&;F>D<=+,#,%6+'*G3F&/2630&&+>=G*E%)5C,9&!"+GC"B#(9#=H,3GE7),:7@AG3:@66<76,DC33GH:C9H&?+$B!C-,4A-=E?>!D7!G).;DB6:FG<*>&;2:#.8C3,-3)>B!-83H<C
@r1298
GACATCATTGATTCTGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGC
+
&C-G"19#A8)*?C#3;3)!9>&9C)+*<=5)G((E#H=B!:#E;H"*F'@..&;2F$?9,%+/
@r1299
ATGCTGCTTACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTT
+
*@(7$;5.7D;$?A+:D+*E?3-*>HC!#A6-,H&"C2F))&4D+1%.6)
@r1300
ATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCNTCAGACATCATATGCAGATACTCACCTGC
+
@3$C>'/*&E70,$?$35/&4-A7!".)C!=H'3E.0$;=+B3B?'9H06E;9&;*;05=@@'?@?%&6*%%$#F5(8#H>,?8+13$<EG
@r1301
CTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCA
+
1@&%?%,-)D;=C8>:?!9#"81-F5(H?*@7B?(3**<@)79<"105-E,!"B89D4&/:F%!6BDD<4;:;-&,$-?E'?598B$4687?/
@r1302
GCCCCGACGTCGGGTCTGTGGNCAGCTTCCCGAAGGCTTCAGCGAC
+
2%6:FA#9<1H2<B-=#$>1G$:-3<2%%7H:36=1G/%*)2-':-
@r1303
CTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCACNACGCTTGTCACCCAGGAACGTCGGAAANCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAA
+
!;2CG!?<)6>,-7H%E2AH073/&"=!@8;=C@F(*<22E(22=C8)%&%+4;!D7589<8H)<234"F87"<21"$?35A6('*-H?'(#@8?4+-,27$54*'0$G?$/?+D/"9?2C
@r1304
TTAAGGCGTTTCCGTTCTTCTTCGTCANAACTTAATGTTTTTATTTAAAATACACTCTGAAAAGAAAGGAAACGACAGGTNCTGAAAGCGAGGCTTTTTGGC
+
8D)7$8+G1H8)+=&@10!F,+HCG/D:"A5/;A##64><6E!"&$9)/(7',(%70:->$-//E<0&08FD7:FE.1<@B6/<D")#&G5!;F-968451D
@r1305
GTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGNCCGGCAGC
+
(+#")'*)!'**$+'#&!+($$#+*'!'$&#$+(+'*''(%%"$!#*%$"*(''%)#!)"!%+)$
@r1306
GCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCCGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGAGACCTGNGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCA
+
A41C06;*8"57'7#E%D!,(:A%3-:><*CC6D$"(5E/0"@AA$G>"&C9<E/2+=9F?2H!0>C*F"3@9EH+'9?#=BC!8H.?=F=.6.=;F72HF%'".$0)A$6#8353;-D9"!*<.F)%2%73HHFC245<#/?7'E"B#"'0;>#?.6@/6%)8E*%EC2G@E('!)7*C#?7E9,'
@r1307
NCTGATNANTCCAAANTCNATACANGTCCTTGGGTCCCTGTAGCAGTAATAT
+
"'*%)"*'")$$()*"&'#')&)!#+#!+!'"")&)($+*$*$&*+!#"*!(
@r1308
TGGCAGTGTGAATGCGANCTCCGGGACGCTCAGTAATGTGANGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGNC
+
55#+5!/'E)A*DE#?&!?,)A2A$/0/D@,0FF7343=F.FE)$G+#.93)26''-<%%?=B:?*%!!?B!1&+-$*!?(F0**$?F:#4#6;:-A,;#
@r1309
AAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTA
+
=D3BE7&&AGA*!!1GG=@A?(<6:'46H.6H'EA'%F.8,H%@)F)H%$-B1:1/":A
@r1310
GCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTG
+
2),6396GDC.B5'>00(;?&)":2;#BD;++D6#-63>"F*>F>4.*("4G58G2+?>D*%@CG-G57=,@)&,A.<H=",7F?3
@r1311
ACCTGCAGGTTGGCTCCNATTATTTGTATATTCATAAAATCG
+
A@3F0$!39/&<E9F8!9(F:%4?7&=B(8?"-/?/:=2>)=
@r1312
TTCATCGAATAAAACTAATGACTTTTCGCNAACGACATCTACTCATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGANATTTCTGGATATTGTCATAAAACAATTNAGTGAATTTATCATCGTCCA
+
9*E>3/AF34B63/'-FG(,&=D(!-&2:!B/7&-8-?B<!ECB37G6&/#3.5%.<63E="&2H3@."<-3*;/@G<.@1?F@E=>736G;!!='/D+-"#(A&.,96B'#2*<7%:=@D1@='-B2*'43<$"5F?F%4<$$H"
@r1313
ACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGNTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAANGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAG
+
GDA"$#/C1!!:.,*=9#!(7"#H5)/&=#2$.%'1B)'86)83#:%(7:@;!+&G7A:"@3H&63*":(&ED!;%$*H718.E71=E?9:-"9-??292.G)*@E=C-3A5>'"7(<0>24087%,CH9/''%@7D!3+0;1(/1"/<847#('+"$*66/8!+2?=><,(>?,+:C=**%)B&2B.!?G$'.<>1+FA&>:G0%?"<7C2GC/=)E)=43-:88E);"%3@=4;0/-7,A;-,@F156'E2B"2F<3-)>3:-G"<0>F:A)-E(H4=H?6)+>*%-(%G9;B6':,&
@r1314
CAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAA
+
$23-@%@,2$=B<48H2<@E/>C?E>(E=50>6:%C!:E48E++5'BD2D8*+*32E2!G
@r1315
ACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTNCCCGCTGCTCCTG
+
2$19-95A=+);+"=:"&D:5?";@1(C2&,B*:+)4,3#&*B.?%!G6FDG8:=2"!;27E1!;5F@&D!@39H.9<;#=5:5=D690
@r1316
GTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCNCAGAAAAACAAAGCTCCAAGCTCAACTAAACTAAGGGCATAGACAATAACTNCCGATGTCATANAC
+
!A+0EF19B492G4-<#/&;1B56E*#=A%/<07*FD6++21D*)"$?#)87A8*'*)E?E21.$(79G.(D9"3D&*'-&%9)';B&*GC$)&D,!*):28%GG2=@%5F;<.+(:<32*F&EF-HA";*?=G1>)4@28C?+&9!81H1/G7&,2*7;?-F57#A8)7E*?)0&>"%G:9,;.$3C"4"#@?%&'>-%H9D23/%9>G82#A/0*&#A4E036H-F%%A?%.='AG%+=?(1#?H>&:*12?4467-0$%=!!C,<C,9!,-"&8!(1=*<D#E8=,5+57E,,809B(:#2D:'$'
@r1317
GCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGANTAACNTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACG
+
ABE6'+658D=:)+F+C:!+:F87&/?">>-#&'8*;6,E-D4B"?13<7$-:3+.=6?G(&A1'F="DE+(E7*+(<8'08*.)4)-AGG$>>)0DE)(/E@*(0F?(&-FA061F#<8+#/>7?G+9&)#4?"GB+=&+#.?D";05?/8F-.-C6,>CC+,@G5/9+?/>$;*;F:H,F,,DA!CB$+6!)!8<H0.FAF+957
@r1318
CACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCG
+
H62;6@45(9.1.CBG9(>%$C76"0/G&9(?%#/-(!.7,.)8=9>A>78"/#4A+)%CH$0#>87@/6)G=F,5&$H5!)762$-%E
@r1319
CGGCNTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGT
+
%%$*$+()&+)%!*!'&*&!%'#%'#%#')*&!$")'##)%+&%"))"
@r1320
CAGNAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCAT
+
B7/1:%E)G982%CFEGB#*24;>*14E+95.:?8.8;+?1;84,3+8);8&(6;35%<5$9?#0H6&+D4.*A(FE9<?2%@5*)
@r1321
ACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCG
+
1GB/?>*43;31GF:H@$;%+2*?F-D4H5G'!($=C?1H
@r1322
ACAAGTCCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAAC
+
)C&GF)0B"%*?4G4'E?;2(2*.+:@',>2+1&1/-/4,,F91-:E<>:
@r1323
GTAATTCAAAANCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCAT
+
)C#%'>0F:>E-?=(1:?:?-G#13GC=.D1#$#<4:'8ECA&'D%09%D))7;'F-<:%!"H6FA)6G74>=7D@79!,1!E74;,E!A@!"#
@r1324
TTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTC
+
C.;0"GD7@=B6!1+&F=H+.=6A*EF60(<=;>?2DEF>89?
@r1325
GCATAAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTG
+
G#'A>>2.B-*6'<'?1"(4!E4$#4('(98B:##&4G5A17C(G.<$9.9>5@B*0.>*5$<.,)@/#7C+:?(
@r1326
GCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTGCACCT
+
1=;#2&3*'(""7$%C@":"'D-?'<-%2H2,AA>E@7ADH%"?+!-H;88%3*E&56&"
@r1327
CGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGA
+
/7!47B$2&=&@DD'5=%)#&:#;!63+44,C<:D,$:6B,;(3+"H9B?%D1%2;?.<C2G)-2:@,F6?*!<5%AE7G"@-0/H?1))F3&))<'4HB547/);/B;088"/.AGE4"*=A:>A*404-'*,;!:,-%4;;$)*8*$;B/?1#,:B,=6;7%"&-H+F22!;$8<!A<?>E7@:
@r1328
GCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCNCCTA
+
)?"G#G51!)FB8/%)9(34>,(:&75=4C!9!A'?E1%'*-FBE0=D01!2&HF<'&AG7'H'F(/,>0&67+7'B1(#>+":=D-&(E/.10-:63&H3+BF&#2B<$-:&618+C<<1:'+
@r1329
NANCNNAGANCGTNANCGCGACTNACNNNCTATCTNGTGCNGAACNCTCGTNTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATNAACGCAATATTCACAAGCAATGCG
+
&#)'#('**$#(*!%")$#$&(%!$'!(!"%#*#))&%##')$&%%'(('$"+#"*($'$#+$*%$)++$+"'$#)&%$*+"'#(+)(#&&''"(*+')!+%!!+"!*$'!*#%)&'"*$'#$)%&(%&!%((!#'"+
@r1330
NGTTNATNTATNANCAGTGTCACGNNGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAAT
+
!!()(*&"%'%&'""*!#'")((!'&#$+$+)(+!#$%*"(*("$*#$+$"+"*!(##(!)!+!"+)#")'&&++!%$(#&")(&!'$''%#$!))%!""&#*&$#)#$#&+#!%!+%(#%%'#(*)*)
@r1331
ATCTCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCNTCAGGCTTAACCATGCATTCCGATTGAAGCTTGCATCCATTG
+
*$$)+(&&*!")+#&##+"&!!)"#+'%'(&*&("#!!*'"*$"'+"%&'##!"%&%$&'*'%$('((*!*!+&)"!!&*+"('!&)!&#(*($$''"*&$'!++$"'$"&&'&("'$*'"*(#+''('*!'*(""++#&&!&')+!)+()%+#%"&*$))&"%")%&$#(%*
@r1332
NTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAA
+
!>F*@&!H1,=:$2-#B2+FF#;-FB<"+>?2BH)!28@48->3@!!2"6-//*%E(-B#)>EB#)1$BC63<9>49?B>7:$$39#2<C
@r1333
GNATATCGANTCANTGATCGGCNGANANANNATNANTNAGGTACAGGGAGAAGGCGCATGAGACTCGA
+
!("&)"*#$"$%%%%(!&)&'$*)'$#!('*"&!!'(!$'++%"""*%+'#)$#*")+)'(&*'#)*'
@r1334
AATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCNCCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATA
+
6)F8,71(+')@8FB1#C#F$@7%E#=&H64;D$=0+59'B%B"91&AF*D5?#F%5::B&%6*@/.2F8G-$(E1,#@F2/A,32&&H'=8G"H9,&H<"(%?03+@F+E-B;7
@r1335
TCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCNCGCTTGAGGATGCGGACACAACGAGAAAGGGGATACTGCAGCTCAGCAGTGCAANCAACAGCACGTCTGAAACGC
+
<*+>B,CF"%34,0AE9#<E>@,<!>)A;&AH76@1:')!258(7<':$/$1)&"C:DA(4+2!=#<7%C9D=4?3'<@EC*<>1,&)/45G@F6'.&4F'3%)5)/3DE#-*!07?DG,GEG9A20EB::.=3"68A7$,2:+'B5@:"=9$H#4.F"DACED(<2%
@r1336
TTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTCGTTGCCCTGCGCCNCAAACATCGGCGTTTNATTCCCGTTTGCCGGGTCAATAAATNCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCNGCGACATAATGTTTGCCGTCTTTGGTCTGC
+
#2&F4(E7B$H=,3F4#2;DE<=0C-1?:B?F$$75%2(#-3)F*6,,)><==>E'>03BBF540E85%@C,H42)H)456#,0<C=).@&(?@/0F=BDAG(2.#9-E!&95/5..DC;&7E1,8AA>*%;59/D+)2!"+8/)4-3H,5-?&/$-;8.!D*ED+!&+%'+44AC9H<E<C'H5%B=?(BD>A9A6%G0*(34'&!B82B72-E<8-0GE90@+.!(!*;81C'7E/;$**6=*7C6DEB!<1940<?%F7#(B8&F"-+*
@r1337
CCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAAT
+
5H!#";%56D)H2GDEF8HF>!E*(!384$$A">E=.'6.(*6A?-%F#69D>96-0/","025F1GCC$!A=2FB50>@H,&&9,-7=-EA;=@456+A5-,0+#>+&+9C,=>
@r1338
TATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGTTT
+
+>0$@@2F804C-,(9@2&AB)B=CD(.$:,(13;->16:.1D'($9,F(H7)$(*".%4(3D!8#3%:*0@B2B!3,($G31A
@r1339
AGAATGGTTTTTATGCGACTTANCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGC
+
"+'+%+)(&&(#*+"(&*)'+$&)$%")*$%(#'%+!*"%!'''&+'"!&"#!'''!%()++!)+!)+#)!%%''*#'!"
@r1340
NNNCGCNCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCNGTCGCAGTCCAGTTTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCANGTCTTTAACTTTT
+
%%&$*(#&*%)+$"%$*&%&*&)+$(%#()((!''*)#*+"%"&!$+"#)*#"#)"('%&%+('&*!+&&!"!#%+&(&'#"+)*"&""("('((!!'*%$$#"))!*$")*$!#+**#*#$#%#%#("%")&#))+'+()!"&!%'&"*#%(
@r1341
NNNNAAGNNGGNAATATGCNCNCCATCGTNATTGANNTTATCATGGTTCANCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATG
+
!($#'##!!&(#%$!%*%*!"#'#'(**#!$)!)$$+!#%+("!)*"")!*+%$+#*+'*$+!&&$*$!!('#*"*&%&&%)+#)"&%'!'"'&'
@r1342
TNTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCC
+
)!G2&@09<97+!1.+$F0F,?88%B1:(GDC7.-**?#D*8E70$9@!1")F87'*?-)+4#!,9>B46%"D5H!
@r1343
NATNACNTNNNACCNGTNTNNCNCAAGCATNNCNTNANGGGNNACNCGNGGCNACNANCTGTNACTATCNNNANNTCACANTTCNCACCANCAGNCTCATNNNNAAAAAGANNGAANACTCCGNNNNGNAGTCTANNCCNAGGNNNACTTNNANNNGATC
+
##!##"!!$"#$"!#"#!$##$$"$"!$#$$#$!$""###"#!""$#!##$#!!$"#$!$"!#""$$$#!!!#!!#####!""#$$"!$$"$!"#$#$$!#!!#$$!!$$#$!!#$##""##"!$""###"!#!$"#"!"$$"#$!##!$!"###""##$
@r1344
TNTAGANGACAGAAATTCTNCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGG
+
#""#'$+'(!*+)$+)"&%+")+%*!&!%")#+#')!#+##$$*((%!$"$'"$&(#$
@r1345
GNGTACACGAGAACCACCAAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTNATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGT
+
)#E22!@0)."2+011/>(>==?91*@>:F&>@C#6E&6!;2;'285(;4)(-F8883455B-1D'DC7'5B'%:B+,G'%E-?>D(F431G-G3?*A'@54?66>%E4.35'!-8GG%(A4-90-?
@r1346
ACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTANGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCACATGGTTTCCAC
+
:-=E1CD<<G)?"-3?/49?;=EB*A:1)$!)(EC);.)9#,,C(&5!*"2BGG+G!B(@?/;DF$4,01A'#3$&@943AB-$#H0D"@$B=HF-;FHB'*8('G+.F5688')#A*1'-,1@202D<!,';$'-!@2C=-9'@(711'B)/
@r1347
TGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATC
+
>"1?/34=D437G=A53'?:%7)@?415=;8:/0)A>,3E6;,,E"H!;H2?,?!#!)73+HE
@r1348
NNACCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGNGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCNGTATGCCGGTTTAAACNTTCCGTCNCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGAC
+
##!&*+("#')&+(%'"(*(*))#!*$"!!)$"*"&!%'!!+)&"$!"(($(&!"%"*#('!"&!!&&'#$)))$)()(+%%!"()*&&'"''+)(%*+*$%!!!*!*"#+!%+"""()!%*'#+)$""&*)#%%)"%$+'$'&#"'!&%#&+*$+(###*%&()&!)!#+($&$')$+!($"%*)!$+%%#$#!#%*"#+(!"*!)&$&('($%*&('*+'+$$$%)"(!%)()&%*$*""&(%)+*+'&%!*!%"!$+$!'(#!$*&%%'+&*!&"*&("'#+%"
@r1349
GCGGTATCCGTACCGATTTCNGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGACTTTCCGTAGACGG
+
*"))&))''*#(#&$+!%#&%)("'++$))$%"#))%+!*)($(+*!$$$%!!$(*#'(%)&+")!+!#!!)'%%)&"!$+%!)%
@r1350
ATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCANCCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGGGGGGAATCTTTACCGGCTGATGCGCGGCTATGC
+
A=@<H+*B#H!%H@@6D.-4/H>/56*"B.><D7:-D75<9#3&42,C77)6B*;(+?;7:G,@19/&-3&"AE."4AB4;&+-#%'.&";#(83>4&:058F*0'FD63'96$$)<@26)HAH<+G'46)(21!%@31'F(4*$D/8;4HA43)(7AA?C#54(!BB.&4%#/.F@G48-54>G.6,!+B2"!4)4E34D*A6986.*/C42(4
@r1351
TGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCANCGGCCTGCTCAAGATCNTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCC
+
27*@>.D4E%$**+0;<9D?@D><*+D-E#!@2D7>0)3(#F-8?(/@<./BG"21))6*D#71=A>#5F5,65A%6/>.DDE%:-'H&-<3A#8&+)!B+0(.4<3B?&G@E.9F-(AD+E8A22+3),<FG-0,),57A#!-00!:/,3G0BD'07:"4DEHH0,49!&<B
@r1352
GGATGATGGCGGAAGTTGTCANCTCNGGCTTGGACGGGGCGTACCGCCTGC
+
65E51/F"7"FCE*6>>C1G/%E=81+(G"/7->G;;1)8D$$H/)A9=/9
@r1353
CCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTATTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGG
+
G?D$7,6.C%;4+*+9/8@?@GAF#0!6/CDE!&134!+7=<G&-3,FB9@@!61)(2C#F=EFE#$,G#B#?@3/;-!7@,?F&,354=%.3/?7+,=/(9E/=@D!%3$.H%B)7?=$4@?#A;6?DB."A*$A%<B))3?50G-.)30D==))=7G3B3(9*!?-@;=1
@r1354
ACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGGTGATGGATCAAGATGCAGGCTGGACTGCGACTGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGTCGATACCCGTGCCTATAAAATCCGCTTACCGAACGGCACGGTCGATGTGTTCCGTGGCTGCGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGNTCGCAGCACGGTAACAGCGGCNACCGGCATGACCGTGACGCCTGCCAGCACC
+
F?,.#+/:F@C""BD#3C<,(;,F)=H)F06%?).8%+=A-8E>:-0/9=21F>/,>7+11.#@4/#-)/#:7%46@35("&2=(2.3E-<?&#.@H"763=!@<AD>1*>D+0=-:)0*!;385"82:/!C%-A&3989'%"2,<>*(0,#$#(G2G<'HE(9D6F20(>+?C$1!;.0F47!-?9%%A#0G46.>4F.73/-44<@;A$"*<%8:(6HEDE$37+>(1$0"-%G?%$6/>+#'1>6@F$,%26E2$&C&FC5?9)6?C6(G*98F''6.&"230*@'1/!'-2/H1$;/#5G%//9$6>!5/6,94*04(G606&+0/7E!#3&/%)H0,C;DGA789&?D30:>/6#94$DF:#>=.:,-?!+?"1#><.F5D8EB0C,4H$F*B#8H#EG;/5"6>/='3$D(#.G
@r1355
NNCGCAAGTNNGNCAAAGAGATANNCGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCNTAATCACCATAACCTGCACATCGCTGGCAA
+
!'(&()*(*$"%$%''&$%*&#"$+!%*+(%%(&%+("!+&'"!%'#$")+*#*$)$$(##""%)!!**'%*%))#!((")!%)***+'&)+#*!&%+#$&**#&!!&$$)+&)!%+&'&*'()&"!%#$)!&!(**$""**%#)*'($*$+$'%((%($&'(("$'*%+
@r1356
GCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTNATCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCT
+
9><9H2"F='A!8;/+54!::*@F+.EH9&+"FFB2GF;7;(H)C9-%C"B*.CD3H*?A2+F-#&&*1075)?21;)47>$!+BD+"H"$&+"%*#AB@4'!30C.H?0$.D7//;@.G(09)?'F402:<9-5$.1%H+2B&H7$E9HGF$&=4:C9."*,8(43H?(;9<%9&$@:5(!FD2;/8%"<95E+4F;73)%9,&''6(G"4:=<%&E6C&"+D".3%>;A-55A:8)/,(B
@r1357
GTTGGAACCNATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACC
+
@$C;7.3+9>9-'&8'();?96E'+</:G6+5D/,3E3"$D4<<,".$
@r1358
GNCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAANTGG
+
)!%&'%+*"&!%*"+!$)++)*'!&&)&$'##'''(+(')*$)&#)")&%!&+*()&+#(!#(#"&$
@r1359
GAACCCGGNCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGNGGAATATCA
+
:DEHD:)8CG%G%80%(A+F-7'5?(-9:<@.5-&(D)$+G(02H28?%/C8"/(@
@r1360
ACACTTTANTCATAGAACTTCCATTATTNTCCTGAAGATAATAATCGCCA
+
"%)"**!*)$'%+!#%($(#+"('("!*!%+'$##$+##*'*$&&*!*#)
@r1361
AAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATA
+
-0>87>;=4B+#99!+3D*2%E5,&D+>D#1(.!B%DG.:3"0/()?!1"0+-,?
@r1362
NATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGNATCGCA
+
!99$);F,!*"&H@29,).5-&H$$35&!D"4@'=97B#0A4)>86H&/C.<%6DE694H83/4/,8:16)%8;3195:*F-!*@)",9
@r1363
CAGAAGNCTTTGGGGTGTGTGACACGAAACGAAGCATTGGCCGTAAGTGCGAT
+
('!**&!+!*%%&('$%)+"+$)$#+)!!$$%#+*''"("'&'!)#&'(""!#
@r1364
TTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATCACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAG
+
$/)?;A@*AB=GE2D78?G-3,GC!9).A%=-4<=>5:?5H=9).09'==52;@7":F3>E.#%*4B)#&-0EA@CG.4D:?(0>G$4.87*?+%%FC+E'-D?'<0&0;$E3(9EC:-C))$-C%B!
@r1365
GTGTAACAGTCCGTCCCACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACC
+
,0&G-).C<+7+@=/%>#0C?=-#G5<9;9=1>2?1>7*''"58/FCF?46"@&6!H'9$F!,8?@330!#@BGE?)".F'');%&E6C6+!2**13.5,5@HB,F/9EA"<&*#D03EF?",;0"G&-&?"5!:A61*2:=;&&-6//8G1!GF(/>#$#?&41BF$;CHCB555<@46B@;075+=
@r1366
CGGCTGNCGAATACCTGAAAATTTATCAAGCAGCAGAATC
+
H2((7D(5D5;<E"A-&!84/'93,9%"#*2$-$#="73?
@r1367
NGTTNCANTNNAGTCNANAAANANTCTNACTCACATCCGAGATAACACCTTCGTAATACTCACGCTGCTCTTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTNTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTNGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACNCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGACCCTCCTGGCAACTNGCACAAGTCCGACAACCCTGAACGACCAGGCNTCTTCGTTCATCTATCGGATCGCCACACTNACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCGTTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGATTGCNAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTNCTTTTCATGT
+
(%%'$'!#*'!('##"%"*&'"(!!%+)'%+!!)&+"'')%!&&'!%+&((+"$"!&!%*+'*$#!#%$&$!+%&)$#&)&%#+%*)*"#'$!%*'*)'""!'"$#!$$*#&')'((#"%!%(%*#(%***$)*%&(#'(%#++('$$#""&+!+"++)'!#"&(%$!+)&)($&%#(%%%#!&)%"%(!##+('%+$+!$&!('!%'(*!(!$*!''#%++)$'&&")&+%$'*'+*("%!%()#'!*"*(+"#'!)('$*+#%+)&'%&&))"!&*%"*!%%$+$$#*$'#%!$!#*((*&(#'&)$$%&!+('!&!%*"!'*"!)$('('*#*'"#"%!#%%"%')!++#*&+*(""""!)!#"'"%*'(#%#$(&!#$)+!+')#$*()+&"%'"$'&&)!$&%!$%!*+$#'#&""*(%)$$(+(*###$&$**(&+)'$#%)''"'&%(#!#)%$+)%##$(!%(&!#%#&!#$&#%!(#&$'#'#%!$&+#!*('*#+*#!'$((+#!(!%*!#%"")#"&&%!")&%#%#$#!"%)*%)"(((!*$))"$#+%"*+&%'!('+%+"$+)%&$((%!)#"$*($+#&"*(#$)(*)'(#"+)$*)&+'!%!+%+$$))"(
@r1368
GACCGTNNCGGNNNNNAGCGNNCNGCTNNATNTNNNACNTTNAGNNCCANAANNANNGTGNNGNNNNGCGCCNNCNNCTGCGCNNNNCC
+
$""##"#"$$!$!#!$$""####!!$$#!$$"""#""!$!$!##$$#$!$$$""$#"#""#$$$"##!$!"$$$#!!!"#$#!!""#""
@r1369
TGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTA
+
31HH'6!*3D/?C@A!?G6--*C>D<9<H'842!*A#0&4B2C25E95D!=002$A);<@6&(<?(1%"/=3<!;D(F5$7:!HEA
@r1370
GCCGACTGGCACCGCTTTTACAGTACCCATTATTTNCATGATG
+
$G(#5!'G"(E>%:?E',91"$=2H<.85--B?+.;E60$9:C
@r1371
NGCNGNCNNNNCAANTNNCANNNNNNTNNNTTNAANTAATTCNTGGNAGNCCGACNNCCGNNAAAACATACAATNCTNAGNGN
+
!$#!!"#!"""""$!!"!"!!"!#!""!#!"$$""!!"#!#!!!$$#$!"#!"$#"!$#"!"!!$!$#!$"""#!"#!$$!##
@r1372
GGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAAT
+
G)/AB,)$>6F:*H8736182==-<$C#.4@'AC7!(=#5.0;5(%<"18*/&22,%:1)B8.@B::(5/=/H-:EC9'G98-1-%/-F15A!>.9*>4E.=#(>.;1%E6G$9A@49=3+E0F.%
@r1373
ATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGT
+
>/;1,4F#+)&1-@<3-#.;:/A'H?*+6<6"#=D9<D@D%"37,)10"2H2G-/%B6A6AA.B9-7'=1BBD39+6$4+:)A-G@3$,.,'%9=':9);49<E"#,/0.1)A9'".C.A$3/7?*3!6,CB'<2:;8+($":C>E/7,#38/6??8076'D"C-CA=):,B4
@r1374
NCGCNAGCGTGANGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCA
+
$:+;C/;A@;)!DG&DB665=:8"#B?+*'>8!028E38#9,72+?(E:=C8/E0>/FH,1@1,F
@r1375
CAANACNANCTNTATGAGCTGAAAAAGAAACCCCAGCAANGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTA
+
&(%!($$*')&!+($'%#'"+&**&%)&*&+"(&"+%"%(*!%$+%$"&!$!%()*(&#+#*"!%(("##&!')"#+'*+#!!+**%&+'%)+)+!
@r1376
CCTGAGCCGTCTGCAGGTTCNGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGNCCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAG
+
:E<'*4@79<29F>%@D<.D,D7+F(0&9></08-,20%DG/C*<:1)/'7!:&8B>",$BH.H!:=G(#C!2C&!)-9"85!5$B.),A@%?E=:17%>#1H>H)?.=)
@r1377
NGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCNCAGAAACTCTTCTAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTC
+
%>+93'B;10!&&,CC!=?0"8/+C?0C3$C))!9-1+(0!+77=-.++FH:,05/+!G3,39&7@17=;.B(F'!!73/,.+:/$%3-H++*9!A-A$;5.!'A/$H"*-F:"?G;""E<@1973#65E)6.*F*#E4',D/H05=%78109
@r1378
ATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAA
+
@*<1@+E&?G7//?>E>?8#6#+#'E.'114<+?!:$0?.G
@r1379
TCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGACACCGTGCAAAATTT
+
)%*+")$("+(%&!$"('))*&#$)&!%&#)&+#($%$&"&%"'$&%++**%#$+$)+(#"!
@r1380
TGATGGTGCGATAGTCTTCACCATGTCAAACATCCCCTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCA
+
&G<<94@%6#'=:B.'?&,D(-7,=34(>"F*@?(G>8?(?4/3H>$?/(-;%*?HE3:?-B<A>"(:$42772H):'<!('!"3+89)/E
@r1381
NTTTGCTGCCATCAATTTTTTCGTAATAGCGCANCTCTTTCACTCCATCCGCGATGAACCATGAGNACGTCGTTGACGATGG
+
+9<:H8'AF$H,15.).0D'5+!+2+G1'=41B&0)">39++$,()&*;49/:!)5>A&+),.$=CD,A2%>0,5$H8-H$:
@r1382
NGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTG
+
'@&)1E57!:D75B5@5*#4CF,6>F80H15?4<8:F.493@54<3?>%+<)@)D7-.008
@r1383
NCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGC
+
$B#>"1$D;HE(=>@56&G"*E8#'*+;$6E)A'4&1&6H6G4=E-<<3B8
@r1384
TGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGC
+
#8"C00H;G,H2@"+#?42<F2E!B;,4)1*+H%+527.5>.=3>9F-+8BE?,+)@4:E'>*=:".#+/F<1=%#@5/$
@r1385
ACCNACAAAGGCCNNANCGACTNAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACAT
+
"'&!*((!*&%*%'!#*##%'!"+""%!+'(("%)(*&(#"'*$&!*&++)*(*(%)"&+!$(""*')
@r1386
CGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATCGTTGTTCTTTCTGCAAAAAAGTGGGGAAGT
+
'+)8%D:H,3%HA20)?48A!'&43?+<&;,+??0?3F+@;%AA*5?2%89.;2+;)(:*:)AB>4F+4=-F
@r1387
NCGGGTGATGGCAGAAATGGTCGATNCTGCCGACGGGCTACGCGCATTC
+
"4%.:7@G2,F*27?078"-#:!)$A:>AF,B<9%.1C!0+H42HD#F"
@r1388
AGCATNGTCACAGCGCGATATGCTGCGCTTNCTGGCATCCTTGTATAGCCGACGCCTTTGCA
+
;%4B;1">BA&21=0-"?%:*GC2=@<+13":?=9@173BC01A;62)8CD/'GD/,#?.$"
@r1389
TAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACA
+
158!>=0$7'425)D@6,8/-!93B<?H51)B>-+#'4E=
@r1390
NTGCCGGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAAT
+
)&#'(!*+))+(!"(%%')'%#"&"$!'#'$'()%)('##($+&$'!+$%!%)!$')'*&$%(*#&%++&)$'%*!&#'"+!
@r1391
CACCAAATGCTGNGATGACCATTTCGGGCGAGGGAATTANTCCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATAT
+
GGH!>4.D+)9*,?)BA6A2.0F<E62HC-4*'9>8FF7,:#6!E$H@4-B&F0/-5>D5#>61">$:AB-!),@/3!)/54'*;+::)!@6E&%/<"-D'966G=
@r1392
ACNNNGTAGCNGTCTCGCNACACGTCCTCCTTTTCCTGCGGTAGGGATAACANCCCTGTTGNTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTNGATTTGGTCGGAAGCNGTTATCTTCTTTGCATTCACCGCACCGATAA
+
"*"*()$%&$%+$'##&)!!**'&#$%)"!'%'#*)#"#(%#&'%(+#$#%**"'#)(%($$&!$("$'"+)+&&+(*+'#('($$*!%#!$#$$("'&!+')!#)(%#"$*(#"))')'''+*'"'"&%!+&#+%*&*'"&*&)'"(#)
@r1393
GCCCGGCGATGTGCGCCAGCGGAGNCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCACGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCC
+
E;,*+':H(E13):,CED8A9;%3&$.')-D03G+(-<<)E.:4#<C!";32.F;G4)9CGAA/AG<<$CG5%0BF08*F?<+<4$!73#B<.":>&;,>#&?#C5$G3H(0C8."';0)@!G9G<2C256)<&H='5>E/1A,!-83?5+H)%#<0&@-4,>,EA+G7&<B,(D'/?'HH)-:+$"C>'"F0/&1&#F.F#H7%,!*@,37>-3885%)6?:'=HEGCC-D8%)4&F.C+5H%D(492'39/;&
@r1394
ATGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGGCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGATAGGCGCTNGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGC
+
#+!+%&#$"!!$%*&""*+#%*)+&&!*#$*&!&&)'*+#'#)%%#("((!!%)!'!"$+#)+#%#'(")'''(&+&!++'*#!!%"#&$#+&)+&&+$#)'+*!!*)"&(+)"("+(&+*'&$(%!+(!))*((#!"#*"))&%&)++'$*(#+')"'%!+"&)&%"'#*&&$*)%#'%!*&*!*$($%+%""!$"#$)!#)"'(!$##!)$'
@r1395
CTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCNGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCNATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCATGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCC
+
'H706)04,@+'9;D"<F+/(G!9,<+8!,<7"!FFD@9#=8&>@>'5486-%,/>?1/@.*89,=G?G*7!7<8?44**(/2#!9-#;,G=@A*(8##%?&0",?")H7*+1,#7:<D.B6C*:(DA<2&,,44;)-,*4%!*G?>8)D,5#A;)!"!-&#0@#EE6:#@*96,69")F1'%9/H+'"H3H3!1@,3%C!1@+!!,61%-")<5AE08.2',%4@'E;**,"+#F0?+;<#C&98$(>7G:@91:/70$G0D>F"A2;))9:0,C*/*#$-AC'E%!6FEH*#((.
@r1396
CTGAGGNGAGTGAAAATTCCCCTAATTCGATGAAGATTATTGCTCANTTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCA
+
EA(<;C&)@2!73HC/G=$="F80E>48"A4E.5F--(0H)<9B91*E!&?'"7E-2?<;9H-,&=:;;"5+)##(<@E1$&E3))46B<6!D/@!0H?%//CF:D/*G
@r1397
NGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCA
+
&**(*+%+#+!#)*%&))$%#+"+(+%)++&$*!$))'+#(&&$&+#+(&)"$+'""&''!$""!%#&(('$)++&$"'*&()+(+)#&*%*!'!**"%"&'&"*)!)'*!'%%&#$*#%''*'"&%%%*($$$"$+*%'$##(*$)'$*%&''%(+
@r1398
ACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATTTNAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCCTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTAC
+
*=6?>'H*A5%.2G5,88%23DD<#%&:"(-'EC3@4?:CHF,/E"("#653+@?@+6@;=;,09-:H"/C4;.!#;$HBA7"GC*1&,4=1"&0(9FF<'<A8:G"#$HC210G6&3.&0C:74@!5)%15A#E=C9&.**$9$)2+)41#F75@D'@$%0&:,#!36*%75,,'.+*$06B?)%8$19,!7-B@*$"+8
@r1399
TTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACNTTTGCNCCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACNAGGCGCGCCCGCCGGTTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAG
+
,)"$)-'9*F!5FA,%>@#$"E;<2.+F'@"0+@A@CB@/;#"96#;$9"+B50$.1!(&A:G9H;B;(9F>;-8(+E4?6-D.E##E/G-!%-7*#*7CEG+(#-5&=9!/0#9722>::B,':H.0.:5:@2(2E/+:=2<:-2("$25--3B7E(*";,<C)9?<%G,?((,:8="/$9@G;B
@r1400
TTCGCGNCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGNGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAG
+
0/E)<'F279&3D6=86=H4,4.+"G4!8FD(1&8445G*71&#+<<-B41(,%B4/A-&(,)4*$8";0'B*D,FF.1(FA:'4;6&%.--@=B4$>?481'+4>F%B4-.
@r1401
NCAGCGCCGGGATNNGTGGAAGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAA
+
*C0)@CH<CH/F+.?$:G;"?$.C1>$5#(1B+H+?9D5=*HAF3D2":95,C*@(1*A-+
@r1402
TGTCACNCTTNCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGC
+
'+#&(!('&$*&"$"(+&*'*$'+%))&'%%'*#!'!+"*#(*'&("*!*%*!+"!!*"+)("%#'$($#(*)"*$$$"(''+'!&$#'*'%%"'%!%$)"#&%$*&($&"'&)")***$!$'$+#$%)""$&!&(#
@r1403
ATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGANCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGNC
+
;$"$BF&B5FDC;A;4A<+-#C"/$F260!EHD.!2C9'AG/7A3:":#0.(E#-0="7%=A6%%87)GD5*G$'<D/0E7%*BF*CD5H(/?,AD#)3;#$-6>%+*H5G1E#A5<G&('=)7"7.)$!H09>>=E:95<CG$$3>0"?>H,64%C"G%!?@
@r1404
CATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGA
+
B0>/ED@&B"/7>%GB#GG5BFC4<>AG(&)9746#F#'=>6;5"%G)'#4!G,%,%7A@8#&;?)<!*<=&</*",8,CE3**D,8'.4=$>.4092C4+(!D
@r1405
TGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCAT
+
?D1!D8H'B8;3C+7634E*.)75>/G!;&"G64/59.)G87!?F,'=H8'"G&A)9-,
@r1406
CCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCANATCCCCTGTTGGTTGGGGTAA
+
@#9?/22=!95>1;#*40)#HB$)2G<<E;H<63(8%+*512<3&8B!*>C9=F"+B%H:3!H(H
@r1407
GGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCCCCAGTGCCACGACCGTGA
+
8BEG"$C.<?"#H,$(5;.3E)C;;#"04=A>D:!"E@=83B%E&E2-8H8&H+?.A)+":
@r1408
NATGAGCCAGCGGGGTTTGTTNACCGTGGTGAGTTTGTCTTCACGAANGAG
+
(:("9A(!/B?A.3;,C&-$16(D>F;+&+*-94'"D<G>E5:0F/#?@&!
@r1409
ATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCC
+
+9!0#,C.8;F--4A9G2,81+*2G(C(D=()AA;-A;<!
@r1410
NGNACACTCCCGCAGAGAAGTTCCCCGNCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCNGACATACATTAATNAATATTAA
+
!'%*$(+(#%&#$#%!+($(*"#&&*#'%'")%)))"")(&&+'$('!)*$*$!%!'+)')(#'+"$($%&'#*+$*&**)+*'**#*"")'%&''&%))&%
@r1411
TTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCA
+
>,G5A#7$%<B4A57C/,D38C1+-7H<"@4@63@F,!?&9CA(E>-2/7
@r1412
TTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGACTAAGAATT
+
'3"-.EF+/0D5#)=F?30%H+H,A@8+=0F9D59E.'!G79;<!"&$-?=%8:7</$,:"4C.0B?53-!)&4E9=;2*
@r1413
TCNTATGCTGGTTCTGCCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTANCCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGG
+
%&#%&&'*%"$%$*$&!+*$"'')*%$*++'&%(#!("(!%)+%'+!*&)*!*$*"%'"(&$')%'(((!)!#+#)*&%&#'%%!""**)#
@r1414
GNCGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACC
+
+:DE5-1"+B+:0,2(%AE=;9!=D9819!@*,'9C<**-"
@r1415
TGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCT
+
)(/HD*E'?1-H,."(,9<$C7G<1#28@BE)C).D93#$@6H(>"E75?31<G&<+@/*93
@r1416
CCTGTTGCAGCAGGATCAGNCACGGACTTTGCCCGCCTGCAAGCTG
+
?=0413D*,C8+#=6@'C78F1%@1*69>;>3'!2H>5F/$>-=.A
@r1417
TTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATNAGTCAAAATAAAATCATTATTTGATTTCAATTTNGTCCAACTC
+
49-#A'E6>+$,?76,411"++AG,2'""!>8*:B1E#3-7,)!3&1%H9#5-"7:?6E&>!H59E:>%$##9)1=18373/>*/!$<,>?A*2922)<$%<G<E.?5G$;7
@r1418
GCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCA
+
G70::*1F(<#G:0?:?00G&?D$&CCFH,A=8-5D:;3)+#251F9*0(C1C=0C-8,F
@r1419
ATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGNTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAA
+
/@'*,+>D-#G0&B9&)8*/E!0"1B*!919+A209>"%E+#3+.F/C5..F9#$E3C?'0C%"0%+)"'9>E7G.G0(=77:D!=8*<#/9#3D.8HC98=:?-?%F"542B#778>0$/EB#G47!1!,+@9!B6+&)E*1+6.=$.HE%/1F!)7!BF+2A5)-=*/%(
@r1420
CACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCNCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCG
+
;)&97@G2;EE>+5,D9E$0$$+?!3"7=-?4=%,=;@E;*?.1>@G*$2&*2>7,7E7$!38)G?7;H2<7HF6'6EB-'H7?7$2$1-?@8:
@r1421
TGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGA
+
AB#5AH/28%$B8-;>G+>4,.-;?"4E+44D)+E/#!D!:,?=/F5.)7#@;AA7.-5*,?B.">93H&A/>>&46+#;<*+B8<)+-&695FF,+-/0)43,.E#!=<-A"<!:A:E2'>(7CA<0$
@r1422
NGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAANCATGTGG
+
%771=3*+'=H&6<-B>):;FGB/#!3)(?(,G()6%=C-%>$9G"
@r1423
NNTNTNTNCNNGANAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCT
+
!&%"%#&$)&!'(!+*')'!)*"(!"'!#$*((&#("+!$(")#$)+)'+()")$%&%$)%*()#%*&$*$+#&*
@r1424
CGNANTACAGGTGNTGAGNGNANCCGTGCCGCCAAAGCCG
+
%"(*##!'#))'*$&&!'$"'*+'%*($%$"'()"!"%'(
@r1425
CAAATCGATGGAAAAGCTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTC
+
#(7+10E,,G4A(G800-A:5<D>G%@?*#76,C./@+4(1/4$0='@3(=5E%2
@r1426
NAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCANGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTT
+
":9@2G/&.:>##1*)@#/A?!','90"$"6"4,6$/E5=B5='D=*D(BEG47%37F;2@5*0E?,?&A@$(EG649%F*;%2""HDA8'C7D;B9<H:?G+HH)?.<+#;4D29,D%((0H$;A"&=C3F:'8>;"
@r1427
ACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGNGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCC
+
)8:G5-@,C7AG=B>;.68(H(/=0.3*HH?6A$7F:0'FD33%C1"'7G"+/H9$,-1+'2%?4:F:6$;A9G.2BE8@AE:"$'4413=*E!
@r1428
ACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGTTGACACGGATGA
+
-?7:G55%*4!??76/,/1B?1&=8!$B+20@1%</3.+76(#A@-*27.12E9B2$2CF.">C96*:
@r1429
CACGCACTGTTAAGNCGCTGTATGACGCTCTGGTGTTGCAATGCCA
+
>/$3$#):/E-:E5D<%'E?.;*%?/-4&1791&AHG%F)5*G,@E
@r1430
AGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCNAACGATAC
+
F/$9,F;>:?+>F5.3B@6G)<;0=-H0@F2G(+B:7E:H7.9
@r1431
TNNCNCNNATNTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGNCTGACGTTCCCATGTANCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTNATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGNCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGNCACGAAACGCCGTTCCCGGCANCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCNTCAGTATGCAGCTTCACCAGTNCCACGTCCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTNATGTCCGGTCAGCACATTTTCC
+
''&'!$''"&*$&+#"!$)!")%(&$**('%%!&#&$"+#"*(%+!!))"('"+((!*%!)+'!&*'))**)"!%&"*!&$&#!(!&(+('""!'%'#'(%!)*#&)$"&&'")+%''*+""!%$)+#()#'$**'('+)%##(*#+*++$!*(&'$$#++&#($!++!%!*#&')&)*$*((!%#!"%+#'%')%%*'&"((%""+%)+"*$"&#(((#(#*"!$*$'%"#!$%'%+'+(!+''"'+&%+&&"!()&*&(!#((""$(&!!#&%$%)*#&$%!&$$)!#('#(+#(&"%!)(*#*))+$&($)#$$$+!!!)%%#"**'+*%*%&&'%)(*$$&%&'!*$$"(!#$')#))"%#'#%%&)')!$)&**"('&%)%+*+(+$(*+
@r1432
NGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGT
+
$8</,7B2?3A3B/28E9&B&H48@$F889?C?&%4%)/F0!+'45-:EB&:;B.<1
@r1433
CTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATTGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTC
+
.C%(:B(>/7!+F4%HB'))B/5852!>?>F81AC-A431/*&$&,1FB"B+6D9:C46.3FA<1#E83@F-G.:.%AE7)4H>#B<*H66A0:.,!8D2
@r1434
GTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAA
+
.>#'@%,7>%E$<2*GF7(<%G-?9>!E)!A7D9),+D:!')&45*G(211G3C->H?E6C)#
@r1435
TNTTGGTGAGAATCGCAGCAGCTTGTCGCGTCAATCGAGCCATGTCG
+
(+*"!#*#*"""&!$&+*"'"#$#((($&&'+'&!'(*(*+'+%')%
@r1436
TAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTNCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTTCTGTTCTTGCGGTTTGGA
+
()A2F92*?@*FA>-C3G>8&05DA81(A@2+:#.5">CG"G10*?.*:FE>+5.$=3=$@91+@%+4>!G*!@:DBEF#9A+4,<366#"4AA&#:GE.41-%%9C/BD#'(>C4C9%8>1G/B-"7:%6#4>#D9<*+<B#"FC++;?*$>BB==D%!$,%75A=71#)23E27C2;%HG@>87D5*;2<1447'><"':E;G
@r1437
ANAGNCATGATTCAGTGTGCCCNTCTGGACTTCGGATTTGCTGATATCTATGACAAGGATGAAGCCGAGCGCATTG
+
)*E1;1/%)62=3#1@)5#(0@?09%=%(1G@8=:@.1A/A+B/+GG)/4'4*.0+*@70$?1<"3,.?;$#$2GC
@r1438
CACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCG
+
B4A0"A.31$%@>=*;HB;2A$+#A<A#*E;*F>#::',5H?),('5/+!!4'761A!91;A,$%7C?$/#;70A?
@r1439
ATTCNGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGNTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGG
+
;&:<!<8%27:+(EAH%&-;A9:.5&!-38A$8>;H<8+)D7-G/'(DED8!B/D%G"<&DAF95@<?.D9<&:.*</.;<H6A+()5#!4G#2*<?B1<@DAFH1!>-FFF!19-(55.CG*0E(C'-0-?0@C=@<?9&!E$1B;;52*8"C)DB7!'A'5+A6>+:42$8A)==(G.5*3F4'3
@r1440
NNATACCTTGTGTGCAAATGGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTG
+
$"+*)++&&*'$"%$&(%!#"(*&'!+)*'$)+$!*&($*$'%##$%)+)*!$%&&(!)'*$*(!)$'*)"'*($((&!&%$#!(!)$&)!'+%$)&+&$$"'"*!$*&!$#+%")!")%&%$'$'&&$***%$)"#('"*!+'"*(#**+&&+(*'"&!"$*)&'($)!+!)"#%('(&&$"($"#***!&**!'*+")
@r1441
TTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAANATTC
+
B,7=)':=3)#G*!7C=>:"&'/B7C*,)8)</G,D*5B?0!=<2+/1#+::-B$7EG(%5G/#G5
@r1442
CCCGTTTCAGGAAATCAANATGTCGGTTTTCCAGTGCCGGAAAACGC
+
6(5.E=?A)@B><$)&3"1.$1*:*:#6:!EE56?#C20#'?(>(,5
@r1443
CCGACCAACGGCTGGGAGACGGCGACAGAGCTTGNTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCA
+
2%G*"7;2'<-0$<B6'<;$:9&+G-D$)H;E>63::B(!"9=F"67-,')9*B#B"@A(%061=E2'*9<)///2'HC$@!,DD?;';/:18/,.",A04B+
@r1444
AGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGC
+
&-.=*?H+'5<H#-@B3<1:+!C..3.F.0>:AG*-78B(E4,3'C#9)G0)4
@r1445
TTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCCTCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTT
+
/%G6&;!))D1$D:-1G?6A#D.?C83$2D=D5#B3,"=&&5DC//?:+96+<6*$0*1FEF$"17%D=9$-8>$:B
@r1446
GGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTCTCGGTGTACCTCTCTCGTTTGCTCAGT
+
+H$E*/6(:)@D$43$?%6.$+E*DH#H)DH!;?D/802$+3B>1304B'B.62A!3*&"!!:G)128+0@)#H=0+E);<&-)3
@r1447
CCAGACCNAACCAANCCAATCGTAGTANCCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAG
+
97,<A?'C(>E&B!'FE%@A=@@0847&.%E-!55CH86G*FBE'27'!"296H(3?3.9D&+"884H'9G3-:D454,;0"5:%*92'!<5D1%G$'E?FG$0*=.;,:%A5(CF*./C71$H5;076<&!$-&A)CAE(/66=2>@07>1/16@"=D7)(C4>-%9DG'%;20.F9#9B@"<.1"CD3"(&B1:F)H3H38.3$8A$6,81:HF",?.&:$+9GH6%H/$4
@r1448
CGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTAC
+
9E,%+7B%0H59=-;9&C7,;53.8A'(B2"G.1E3BD=$=H"5/@8($3,E2>>.4&/;>"#</C<4;6,2/:7=A=E1CD@<"<>
@r1449
CCGGNGNATGNACGNNAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTNTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGC
+
%&(*!(#*("')'$#!)$+*)%(+!(($))+*"&"$+*()#"'&!)($)$($*+"*"#$'$""'+*'#"&$#"*###"(!)($$%!""&"!'%*#$"%"%!&"&$$!'&+((#*(%*)$!&"("%)'$
@r1450
TTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAA
+
,#/,3*-'0''7=H6.B3H%2@H4+(G;5B)<5/C=0:-3<B@?0+AB5
@r1451
GCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAANCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGC
+
B;6=;;H602?!/3!19E/:8109(G#H<0%";1(;/48"!%,*E&#)@.!5'.EB/9//2"!=-,%GG'(A%=5B'/,D@5C3D9"9B<
@r1452
TGCCACGGGTAAAGTTGGGCAACAGGGCTGCNTCCACACTTTCACTCGGTGNGTTCCACGNCCGCAACTNC
+
?!)HB4$,--)'>((C4@=%:6217*7H;(5?$C0/&=F690!<.??(&2#7/7.#?(316(@"C-/&+%&
@r1453
TTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGNAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACNTGTACC
+
G8.!'+B:1(5"&&(=D&C:'FA(4>A6<"7?93H<=7.83H2$*2>6C,2)/"=9B&;A6&.B!8-+4BB,:G;0+E1>CG-!5F*1+5=7E:;&=:$+.G".0%4;/:DC6':2*F>E+;.+B/'$)$;&$$-D;A!.E,?7'%@&/GF'"G&(4,C"EAD</;(5429+#*,D,>=HE><@+>=E8G)751!7E0
@r1454
ACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCT
+
+$*$<%;&@;!DC5!0GE2*3BB&H73!19*)11=E),==9-7H90@<!+C8&C>A6BDH'35@2</$#EE2.))C)=906>.#-
@r1455
ANCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACC
+
$#+"()()&*($+&)+'++!#+%$*(%(#!##"$++''('+'("&$)*++*$'#$%!&+!%#!+('')&!
@r1456
CTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCC
+
&9F$6<-!6$D?!C6;)B55)6FHG!'=19-H-HG6#&G!'4/.2/#16D(B$59=,HA#HD3<<0&$"<8*=<+@-#5+5?.)BF#GH=8&A!:,22;F/3$0CC:31D><F1:=&@;76+;?2$";?,<=&>E@9'E)D.E6=.;H1H$8.&#F7-5'@7203(F(2-&001#)?F-"74(#/B?#B"?
@r1457
CGGTNAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCNCGTNTTGCCGCCGCTTNTGCCGCNCTTTTGCTCGGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCCCCTTCATGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTNGCGTCTGCCG
+
51B-+#+!D!F:>&?#&,1@#-C*A;9$42;!/B2.*F#9?5A6*?%:&*3/*G/-?8;4"=)9,A'8G/)B9:1B(3:19';7?92@3"A?CBFC1-.60,!7'E9%F"G"+4(A,=8!7B==9.)D8A38;25$8=?=:+1?<;6...E::=-AA=4'5!!9'$A>9:1&H$8&D62>-*<E'9@1&G6F*46H,B);G68?A""%DD+:GD'8A'.=/E<&:F76#79/#G!78D5&*&6H+(F6>5EG;<!418HC,5%--(D6<A(&1%*5"48*;,%7F%CH>-&5:C<1/47EB93E,EEB>(E<:F@,/4HB><+:2H%9
@r1458
NTNCANNNCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGT
+
$)!"*"!)(#(+")#%"(*)'%$($%**!+#%)'"%"!)"$%'&
@r1459
GTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACCAATCAGCAACTCACAAAACGGGATCGTGAAA
+
7,;E'9GF9<?$A;*?9/8<6!4C/$F(A(!BB*@CH5=<:;*';<-736/8E9G-BCD%8;)--4<0#G(%8?7&)(6
@r1460
ACCNAANNNACTANGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGA
+
')*"$$$"*#%%$"+%$#&!!"$!!"!(%%'#%%)#&'&&%$#+'$)'&#*%*#+#$'%$)%'!&()$)$**#")%(!&$()**%#*%"""'#"(+*%#*%""&"$)%%
@r1461
NTGNCNNNCCNCANNNCCCGTNGATGACNGNNANNNTNGNNNGNCTNNGCNCTCGNNNN
+
"$$!##""$$!#$"""!#"##!##""#$!$#$"#$$!!#$!!$!!!!!$#!#$!$!!$$
@r1462
AAGCNAATACCGGAAGCAGAACCGGATCNCCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGNCCTGA
+
*63)HGB(>:6A;;1=>ED7EG4C%$(*<<(!2!%H6%'6H91*:9"B!:,038,GH9<8>94,91)B44?1AA6EC2$H%<,>.:%>#A>=H+96D6.7&7$H
@r1463
ATCTTCTNTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAA
+
'%5-$E;<3((6?HG$/H9+A@)8C)=3+GF2,.*57=-.7=,D*%0B:4",$9="*+&9@@C?3'8A)B(77)>&.#.3
@r1464
NCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGANCAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGANATATTAAAG
+
#:4@,G8,#>CE8/!=;,895483AD$4(;"A;#$$%837@3&G;59=A?B((**!3H.1->'A#2)$"<4C"F7":5A#!>197-$DC,EBE9>%'*B)F(3'$!*1"8H4CE1C&'4,:<52),3EF!*-8/5;#A<(!>#;'*3&H57@8:<
@r1465
NTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGA
+
"+)%+!"(!)'$"%&""!)'%"(#'!!)%)')&#'*&*#'+&&#*&)'(*)("&('!%"+##&$!$%"$%&%&((&#'()$(&+$)
@r1466
TCAAAGACACCACGTATCACCGCACCTGACTGCTCACCGGAT
+
9?;2C)=#3B!D&0A*>9EG'BGG64+&#*=$!3@B$E1(AG
@r1467
GGCGNGNCATTNTNACGTNCANACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCAC
+
((&%#%)%'#&$*&$&('!*#$+$)(##&$")*#'$*&&*++()%%)#"*!(!'%$%$!#*"&$#($*$(+)%$&
@r1468
GTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCNGCGTCTGCCCG
+
A7146'')%==160!3$0F&E(H92)G:>G14,9#8.<<6B/+E4F2.$*<
@r1469
GTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGANTGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGT
+
:-;<&3A;#/FB0<<2,GG/;&D.A<@'E',.E/%4+-!;A<9!FC$@>5$.F):!EAFE-/>,.@)*"(%"-58$=7+1=1<<17'"1D*&>E#!<6&%+%FC4'#37H3,""*5>&B!>'..C'1?.8"$"@0()>54+:-<GF0%3<!:)FAE7%2".7*%?C;-<5A:0*21-"&/<D&/3;<"0037=6',
@r1470
AGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAG
+
(&9@>F3D8A@<.A*2+F::6"D"@6E(8+":*<>!1;,:<0
@r1471
GGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGT
+
2?'@9'(!!:@;/D??06H>*)),65CD:B=;9?G:('82-G6!<.
@r1472
CAAACGCAAGGATTGCCCCGATGCCTTGNTCCTTTGCCGCGAGAATGGNGGCCAACAGGTCATGTTCTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTANGAATAAGGTCGATTACTGATAGAACAAATCC
+
:2+A+,??/>H18&:9$$G)/!)9&;>C--%HEC004>99>D<$98%2&2-"B3@D);C@G=HE60%-=..&B"<G;A;FE("A>E93=6)E:4>8*H-96:G'A")A2E==%A?#H6':$8$)3+8;11B7G<5+-&+(#E:G/,'7@?9+
@r1473
GTCACCGCCTTACCGANACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATNAAANCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCA
+
(?ED".;68!#007?G#?,F3+$5+7?0$<GH6H$&AH4$C(#?*H/E%1B>7*=0%(-+3A@472;6F9%0:9$H7A9EC=9;0F>F52.1<07(*H>?F()B,A!850976%089%E:B%-,02''4H%,=-81A$$%B,/1!
@r1474
AAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGN
+
C'0;C?!8%7C"%5F,B9#,/6?DA*H1,.);C35@5$&E6'D0'322#--/8"?>&!:+@E8$,/?0
@r1475
TGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACT
+
9B2*!E1(<*:!/>=?E$>=H3,"65,5@.CG#2E8?6*7?0"00/:E-(#3(%FD('81=(,E'60;:A,F!
@r1476
CGTCCCGTAATCAAACGACGATGTGGTTTTNGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTA
+
1&D9)E@91H;0>A:?:=9"5A:6>*H)+.F><'GF3.2;")=08.8=:.(F8-423G;G'>A;*E68@A?!
@r1477
AACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCAATACAGGAAGTTTATCCACAGTTAAAGGAACCAGC
+
80-GC5,$BD79?+81FA+A/!($B<1$C)E.')C'8="G==5D#4H2;F@F*G%HCF;8-#?0>G-<C!',A0B)>5%62A1:1$1+'0,+0;HGC)(F*?6H/EGHC:@'DA0.BC
@r1478
AAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGT
+
4F%8$@EG"=4&,"D%F=*7.2D:-/$".G(-&"-*0?/@9)7:C#E0.*6.BD"@5E0E&G*;9-D>CE0>1HGA?5.8#2=$?(08;A+/(>5/8(CDBB#+%789@62>36G:F=.G"HAC--4(</GD%<1?0/3"?8=*3//:3;-,*G85AH,FEF,HDD#=73C!+=(FD!-7!8+:<=G,4G"A0;*6,;
@r1479
TGGTGCCAGCGACGGANGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGNAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGC
+
E($1'1C9D9!$A/DG(24)+%3.)2GB1;).07($H%,$1@E,A6%/"&8G80F#@"BHF#*58@2B(/8+'/:C?*7&D6CG"8D'!+0.
@r1480
TNTCTTTTGTCCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCNTGACTGCCCAGGAGGCACTCGCGACGC
+
#'&&*'%*'%&)#%%#++'*)+)"*'$#++'*#$(!#!)"*&)))$$##)&!"#!+'!&(!%")$)'(&#('")&(*')%")($+$)$('&'!$"
@r1481
ANTCTTAACAGGCGNAAAAATTGCCATCCNAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTNCTCGTCGCGAACCGCTTTCA
+
)#&)"#")'+''*+)#%''$""#&&%%%*+)$"#!***+'"&$#''&+)'%'#+&&!$(!#&#&")!%&!$%%'!%(*++("#*"%'*+"&$"&$(+%+!&$+!##(&"+)$'!&&&"!!"*(!)#+*$)(##)+%&""*"'(*#
@r1482
GTCGTCTGCCAGTTCTGCCNCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATC
+
@>6"#2D7.D;6=&7D%7F*4F'HHB'AD54:"6$<!3A9C*7F'E?@F&E(E0;+=9-D=+;4D?*;:-$%-GA20'284
@r1483
TTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTNATCGAAATCAGCCACAGCG
+
<%(6(2!.%&",<G)..H8H;7E,5(/8'C)8%0:>56::!6)B9!AA83$'$8FA
@r1484
CNNACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCNGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTNTGCCCGTCCTCCACGGGTTCAAAAACNTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCC
+
($3C=1:85#)F3,9;./03,/0CF4"7,CD,%>,*>8A"B:1'=EE4,:/HE,$!,-"5/=(=3C2H=2!+9"4>H#%G<?.?%:C%2"GH'+($:2'3=%+58&H;/G5>.0=9@'09GAD7G4'.)7G%=79(:.(+"EA"+>(53A"1*5-B:6&:H84E4AA4?%;+(9D>"+5,E3')("C9GF>A2D3C*H.::GC:@%2?<43??<%(D:!'B69+//A-
@r1485
CCATCAATCANCATTAGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTTTTTATTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATNCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTNTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATGTTCTGACCGTACCGCGA
+
DACFHA@<=7@!*<!-E/:<4!)685D%,*$1'/3:,?)934+0:HA*'@='1@"D#4F5=24*766;1F!89943?2:2<9+B$!?"=H&1G+(H(8,9*:DA2#=9./>%691="21BE,HHAH05'#2.#/3%F#G?5FC22)0?:(-.C)B<E(7$6>E2A%0H9<+8C#&1,/4(5,E+&F79?%A%&D47D:??+/%?7H#0/0..#'G9;=77"EE"762B4B58C/F4G<8?/@,/@8!/)D)/9!18$,%(BH@&C#<#*@2/,#!=2B##H@2;EE6GE$2A=0.'4$8:3(:'&:0/%08B($GEE9$3+.68D=&$-,B#@2$8059B(6G'6A
@r1486
TGTACTGCCGGACCACCGACTGTGAGCCANTCCGGCCATGGCGTACGCACTGACC
+
5)=5H6+@G/*DF@*?)B$82*(A"%5"0+0D5-59"<D35'%96C">B?+">(A
@r1487
ACATGACGTTATTCAGCGCCAGCGGATTATCGCCATANTGTTCCTTCAGGCGCTGTTC
+
7"'#6D=?)?D0+=0.)/0:E7$5!?-HF6##(DD!)"H/5%7A)B3'6"60.6:H$5
@r1488
CACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCNATTACGACAAAGAAATTCT
+
/#+,34":370FH18",$3773$'1(:D4@6?4CCGA,,.F@.*8G2C#)H=&)=/744
@r1489
GCCCATATCCACCTCNACCGGATCGNAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGNACGGCAGAAACTGCCTGCATCTCTTC
+
'DG/:784?@+/0#2@:1*?*1?<FDB3C74$0D658';#%3F9'=>@>90+6EC;='#G1(AC@3-93:!2G6%571-('&?/!@C
@r1490
CCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGA
+
$D+68!&"%#="#)F:''EB$;AE2%D<A4D8,4$;8'<CCF':)0$!<6,$9!
@r1491
ATCAAATATTCCTGATGTATGGATATCGGTAATTCTTATNCC
+
B;DF@H+0EC,'585.;(E>E2BA'(+A<9D&/-;D(>8>##
@r1492
NCNNTGCGNNNCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCA
+
$&!"$$*"(%+#(!(&('%%((%+$$$')&)#%"&('!*"+*#)#%"$*)&)$')!#
@r1493
TACAGATAACCATCTGCGGTGATNAATTATCTCTGGCNGTGTTGACATAAATANCAC
+
+H%3A<3)5.+75#F16"H*@;:C4.AG</2AD>-@=*!'$:9:F%!8$3'D,DD&0
@r1494
CCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACTGAACAGCG
+
G56F>7<8.%#4#7:+>/F!>3F#7!++G6B9G!$B@.2&,E81$CE!E""F,8=6C7FDG.4@
@r1495
ANATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGGCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGCGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTC
+
'#<.$B#">;)0G;0*':E?"..3/'>(%>46$E=?%4<<-C&.6*8BB6:%B/4354@7/90(F#)6A9F9A==5;8>".G6!G=:*,86"H.596*6(>=-&#/.7A6>?968GC=>(.:5H800@896A)!0)-:'@%,3740@7HD*F$22/54H58%#8$2D3?+
@r1496
GCCTCAAGACGATCCTNAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCNTCGCCATTAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTNGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCA
+
<@":@=-?'BB@$0/7$AD4<@6;B".)>C(D'=>.#40!E)!A:7A%F4A)FD54,7=-5@4,4F<=!7G<F/15"4&0(-D&BBG:14?2C(-C5>'G,66$=:;'B?)#$''/5D:.'<!F%7,(650,:BD%")-B=88'.$5+>>>7'"C;0<+<415,A<B"F70E'E@:G+$.B.%6H-7%6:2/0/0)*0=E<8B#D%1)FB+A)#9283',/$F%7!%'A#B>B3#HC04456*@;G5@24?1/#6<#!4&=DH++*+1H91/.#,#7*)+69!/8;BE7!3G$7796+GA/::!!<3;4?"A!+BA,:4"A-"+C3B6E,*4)2:A<+$@##(1G&.-67"#.&7H7"$-E'),1
@r1497
ACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCANCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGTAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCA
+
;2,".;<;F#@9,G4$-20C.E=1#,5GEF7C@4H+7>F1%5+7H0#47880@-74;B$*>'64*:H>."6C?H7?"E/8$@,&(!??6C53&"$E53?)::!,'-?!A"F+"FHFDB5#&H"&!+#3?B9CB:541"FCB?D.?'6(37-92#1B;A1G/8/9:?AB(0,
@r1498
GGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCANTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGAGATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTT
+
&2+4%3@>$6:.E/>5</F+-&)H270*AG:61:H;C%<%@8F-)@14??4BC21"%9!AA7F6#"24="64$),??6!5&:#:59&#=9$G@2C",1135;8)@A:8<,0+6G1:.$<B565/192%C3G=4?)>>$9%E.?68#$?5.6(:BA*1);AGA;*#6B0F7,"C9E29=
@r1499
GCTGTGCACNGGGNNNACGGNATGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTNATGTGTAAAAGG
+
)'(%$&''')##'"%#"&#%#)"%'+!&&!#))%+"#$&!+'('+#)%!&)'+$$*'(++&+)$&$#&+""*"#*(")!
@r1500
TGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGA
+
H*<2@2D+"G?.+75B<DC#275%C&6&3'2E.&!:*!3!>.1E"%A<+>:B+91=:5B3<:)1>0E0G=5D$!4@F993;"08;8=AE2%"(D24$%A4=2;)(5"=$(&00%(>/A"597)A:(%":8D0CA/::$/&040&=3.AH*9A7E;?9F->C6.ECD+&@)><5%D7'!-@F/1H(8BD<GEE;#F&D(2
@r1501
CTCTGAAGNCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATCAAATTCAGACACAGATGCGTGATGGTGGCCTNTTCNCCG
+
:C.1>4:A618-/3'C303$;0C;E.?)%5$>2$5%?=H1>C6.#<#%"1F%+6?A9#A8@-B0-3)8D81!>#+0"4),9*==
@r1502
GCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGNTGACGGCGANGGCT
+
:,:"DA4B216(>B;B'!6<;A-?(6?D&>9#749?,29FF9?34@0;G$2B2596'A'E?G".(A?*+F&)%:@*.2%-&C89=!;.>-"D@F6&'H8
@r1503
TCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGC
+
*AB&!C+3((1C;0B.>47G;#G3DH2//F:HFACF29@98;A-29-39C>2%(&!?G=1
@r1504
GTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTG
+
%(C%$F0,6H=.<E5B6>((89(5H6"'D66/BH706/D>=-=#.$9.
@r1505
GAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCCTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGNTAAAGC
+
0%6*@H6".2=*5<@?G+E+F,96(7!343.107G<98/).;7)05+@#=H5)+&,G+=:H1#.?D3)0?H=25*#E%>,!$E(<@,'-=<0
@r1506
TTTTCAATAACATTATTGTTAGACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGNTTCAAATTCAAGCGAAATAA
+
7B7#&'6H48=+%#A12()<)F.1.<%#.=1-8C:2H<3(A0B052E:#%)A000B6E:D0),&:E8:7,&*35+;H7>E8-@1$'G%0,*7+)=20G;/D"22<H&,%E/E14$/.+,">?
@r1507
GTGNCTACGGCTCAGTTTGGGTTGTGCTGTTGCAGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACACTTCACAATTATCGAC
+
?%;E36%+G17<;.GC50*#=#@-C23/#(F2!/!608//$"#?C!E@G60$HF?7,$(;2BD8=!-5-&26<%'5;:.5F44D&2>3!0F>42@2"+'.=.;<ACE0A56B23A85FF"D$:$,5,-2/-!2963#(=F346%4(4<5D-C?8
@r1508
CACAGGCTCTGGCGAAGATCGCAGAAATCNAAGGTAAGTTCGGA
+
A;98F6*(0@#6@12CA?#D'=H$%%.G)$A'%2<"9'5<<@*F
@r1509
AAAATAAGGCANTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAA
+
")7CA)8<9HB2?1;!4"7H18-$<>/<(4-3,2(35A8B<7:).C>0F(>8C==<7F/7+%7';>%<=9(;F?2&HG)C2#2))&5/BC#!%A-%"'&20>*8!1
@r1510
AGCCTNNTGTGNCNATTCGGTATATTTCAGCCGTGACGCTTCG
+
#*)$($!($#(")$$+'&+!)*++)""&%'''&+*$&&*"&((
@r1511
TCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACNGGCCACACAGCTCCCGGCGTTTCGTCAGTAACT
+
+B!"DD+"A0=#D)4@$C0-);B+:D:!3:A!#H!79)>67)$E3A5GF(4)!@'<=D;#*8!@BA-7>
@r1512
CCTTTCTCTGTTTTTGTCCGTGGAATGAACAATTGAAGNCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAA
+
1EA;&;1+0'''2@2G(2:"26:!5)5?+*-FD<*>8:9*;5F,-FD?34>=&!?B+HBD(<:?7"8H8C53)&4G;+EF-6(;5"&@%9G!<
@r1513
TTTTCAGAGGGTATTTTAAATAAAAGCCTTAAGTTATGACGAA
+
?@0=6E77""),@=947;C52D+.=,5;-@9<$G87=864BGC
@r1514
AAAATTCTCGCAATACGATAGAAACACAAGGCGATTTAGA
+
D@(D+&+H?F)A-=B*)3.*)>@>!4+HEH:BH4!*>7&F
@r1515
CAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAAAAATTCCCNTACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGA
+
*+>)&;H3<H#1+.;EHDB)"5;<G*3F4B+39.8;B&4(D:ECB?/</@E(G>9+8.@!$:;!@0>)>B$G>!(?E#B1D@*E09G@:E,"7'%D4H*F&G=<!G+A4;-=38)*8BH-5.9-?0*#C*%#$4=->5@-:*!0,)669A4B</7C/44/B%17<=
@r1516
CGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATT
+
"A=6@GH;!9A3)615.H+.#'8!'904!F5#*.>@)&1'6""BG$H.31>;.+E8-8:!%0
@r1517
GTCGNGGATCGCAGGTGAAATTGCCAGTACTCTCGACGGGCTCCCCC
+
,,=:E0A)B<>D='(/(#8(B@GHEHDA&D"$,EEE?.;402"@9F;
@r1518
CTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAA
+
.$%94E@(?9>&%+'8<@<A(&G!>*!,<'"B$,!,1FC"E$>'(;9<H)7E?$)%D>B%=(C)FF,,(25!
@r1519
CGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCANATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAANATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCC
+
H+42?-77<'+=8G/0GE"A5=GF0.@4.=HF-;/)-D2+/1$.%:B&B06'HD/BA@13*'4C+5-D#D0?AF)H*6)-5:4B#?>5"H&:;@:2>0!,0%C;A/<=64??!!?A!E?G802."=4#/:+3"3,)F<0!'/?.AAB?A4452.A6<=FD4G$C0D!#G#&FDD@@AD5<-3E2/4D,6?48;(;9';2C4<6$*#/4?<5%)$90*;0?.*/#?=17+.:8?>;:5$0.B*!G42>*(=(($$G@9%+*
@r1520
NNCNGNGGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCNG
+
$('!'!#(+(*'('!)%*!)$*&#(!%%&+"&+&'))(#&*(++"$$"$&)%'$'(+##%)
@r1521
NNNATTCNCCGGNNGGTGNAGCNCNANATTGNNGCCACNACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCG
+
"!&!&%*%)&*!#(*$(##"')!*&("%#)"$!#(%))&+!+(+*+($'$'&'((#$+*%*(++*((#(#+"('"(!"'+#*&$+)%*()%%'*(%+&'%"(&
@r1522
CCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAG
+
A?F7/(.@,&A1$B?(;7.);"//F)1B<,"4$&,AD)?("$"D483393@"+@&%$65&"073?H<1:=H3G-5CE+3"B@FF06?(02:'A+>5,7-AH@E<1EG/&A)2D$,7CE"'193">
@r1523
GTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGC
+
-"G>%-ACH#&A$G75%0@@12$E":D:8DE$#"F027&2CE'
@r1524
GCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTG
+
HA3"-,A)B?>C***A%7*#8BD80=-4),42'1*/H5>'*D!-G'7')><0<.1FAD
@r1525
AACGAAGAACAGAACNCGCAGAACAACAACCCGCAACATCCGCTTTCCTAA
+
=+H88!'C/D97?+@<+#+H*4#-<3(92F*>@.#9=65119"E:"@':4!
@r1526
AGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACNTGGATACCCCGTNAGTTACCCGG
+
6;*(B.G5C7!$))E*(2*=9>(<#8H%'&G0H-(DB=(-04#</:)<A(-8H-C?3B+=?GD:7(&@63H(3("($,1:8."CG/G,=G*:.>5H38.B.=D.8!9857!,*03,7)0..$@?);21
@r1527
CGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGT
+
.AA)5>06)/!G?-+&*#.87@%D=0(F*E".-9?2.C6;969)'94A/B2#@6#2.!5=8C(36#FA<-,:,">C
@r1528
ATGTNCACATGTCTNCGGCCCATANCCACNTCAACCGGATCGAAGGCTTCAC
+
&)#(!''$$)"")*#'%*$()(&&"$+"'$$$#&(''&'!")%+*!*(('+#
@r1529
NGCTNGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGA
+
$9A:8".2;3<%:=9-E><9;70//*F%6B..-?!63)%8,FA)D(#684/G)C1G>0';$%H)$#!.,>/7ACD-;</$%!<*:5''20$#>;<6"-D/!=5:GH":/:)E1*@6;E(;(EHCC97'F:-C@,6#G/"+%0:=)D3#F*0/'30-G8FF4/8@">#*<#>&6,DH*;2CH1)#-"H*1,D:#5E9B/&
@r1530
GAGAATCGNTGNNAGNGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAA
+
*()()**&*%(!!"!!"%%)+*#)*'*+'*)**(%*$&'($$!)%&#*+$"+*+"&$'''!#$&*%()&$)"
@r1531
CCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTNCGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGNAAAG
+
;/HG(9EA?7%E'826;9.4-*0$+0%@=F45/,92F<!?:F.G/=*&;6C,46>4!.*1)GH0F,*F4D*6%B!$"?<G340'$"45/
@r1532
GAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAA
+
B=A1=?H&=>/4B?11H*$&<9+3550;6G27D-H&,:?)!()-EF$$2)2ED,7(."3,/$"@(*80E
@r1533
ACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGT
+
B"+6GAFD#8!F70FBD:*$E03B,,1E@5A/FC7+H:.@)4:1
@r1534
CGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCT
+
GB#H31<<5BD=/D-=85D@>0(A3!1F".%"$.B9AA<GD=,;6;EC1'A;F
@r1535
GCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGNTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGG
+
*>E:'7?6F%"A->CE0+44$9,,*2:>9$#(HH9,/73$=,>'6.F6)F?+#*#+;@&D$<>$:B><+-?6CE;+(21E,01<2%@)8&:=D5",6=<61?E@-B,+=(%@(:C@+?)E=):35AD!HB;>%5&$5@"
@r1536
ATGATCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTT
+
F6!A.+#);E2)7#A33C1EFH2BB!)H40D&A,A?$-**%//,A:'G
@r1537
CCGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGAGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAANATCACGAATAGTCNGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTG
+
'$(64*!,):H>%:=2AB5408"*@C"(D+')F!B)0=A3>B%*.D=;*?DB*C69$?>1B%:,'6!>=((=F*'?=&&2HE-5(08<?G6"$6DAG6EE8).3.91<<3:9AH:%;06*.;<)-)>0B%&,B"#-E%/E#91?!921.'8'=*)$+"33>EA8(3F3<7H$47<:2B48'8+D!&8,;8B%C;9)(>*/*8D*<34G(,!>-#*!;)0@'7;%;5635+F.-96%-*(.!62.C4,:!5*DHF1B7C8DD.4<72/C5;-<6GD%(60B!:"7;D32?H('-;6A.7A,H$(GB>#<"FE#.
@r1538
TTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGC
+
!B<H/9B,):<F4#03E&"!$(-&!,BD@&E8C5$-0+!-.%=@A5'4*>@G9>15&%!$9!6#=758D?*-
@r1539
ACNGNAAANAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTNAATAGCTNTCCGCCTACAANGACGTCATAACCATGATTTCTGGCTTTCTGACGTCCGTTATCAGTTCCCTCCNACNACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGANAAGCGAACCAATCGAGTCAGTACC
+
')!$%(*%!++')$*%!&$&*!+(#!$$(++&%&%'**&("&"%(('*!''#'#&!#$'$)&"&($("(+()(")"%!+$!"##"&$!&$"%#!'!#!)+#*")#'#++&#'"&"!+!$('!!$!)('!#)&*$!'%#%*%!$%**)$&$&"%)#)+!%"$$#$'&+)'")*!+#"(!++(+'((+"+$&$$'(#"*$#&()#&"*&(')"!&&$)!)*#)%*#($&)#*#''%')++#*#*&$#""+*$"#!"'()""''(("$)$++%!$!"!#+
@r1540
GGACTGCGATAATANGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATA
+
0.':FH+#%>:.@CB1.'=34B6<3:#?'&+6D>.:(2B'=$:''C543>-)0=;$-%#,?<&@@6D%>F9!>39FG6*A)E8780C:=DE-;(@=4.$!=86#&,'(>
@r1541
GACAATGTACCCGNTTTCACTTGAAAATAGCCCACCGTAAACATACCATGTCCA
+
?G!A<?6!#<E3.E@A=6FH+G$0'6)7H2$:?3':C9:B*B:.#>D1<:5#3(
@r1542
NCACCNAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGTACCGAGTTCANAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTNCCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGC
+
"+*)"+$("%*''+!#'*##$""(+$!'*+(!("&%'''%#+*()*$!$"*$$+'&'$*#(#+%)+*(*!!+(&%)')*'')#!)&%!+%$'"!+"*$(($*$#(%#"&!$$!)"'&"($$%"&"$%*$*(*)"'(+&"&$'))*"!%(+"")+)'!)%!+)+*&($(!!')#"#*#+(*(
@r1543
TTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAG
+
G/";;,2/>B:(;(:%+F;57D,%:>CG<C0"#1&F%4;9;'>7F(#'H4>
@r1544
NGTGCCGAATCNCGCCGCAATTTACTTCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGANGTACACCGACAAAT
+
!'1C0<!8?B7,C*(D!A%<.A;$9HH45-HB$$$5!@D2D.89"#8DE%8-":*&$,,75))9),9-85-G,;89G67/H,@4G6%C(EHHE-7
@r1545
GATCAACACTGAGCGATCNATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTNCCACTCGCGCAGCAAAATCAGAGGTAAGGAG
+
:'D=#2?/??>5%-07:F@;GG?0FA6!0&<?22'"<838/G)=.H(>E>$$8##5D=:CB*/&(G<7;42'=6F<F1C;H(90)C3-6<(D88.!7"&&
@r1546
TGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTNCGA
+
&6#59!<G3E6E.76E06&.320+!BH'9+65)("-F4!3,"A7E.5!H++/E.1(;8F=
@r1547
CGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGT
+
7'6'1G.1+C1*E(C:AC.:A3/0E79;&0<G+,,FB6*-F38)518A8>,*78::7(?965!7<#:"01G
@r1548
GTTAGGAACAACATCCTGCTGCTTTAATGCTNCGGTAAACACACACTTCCAGCTT
+
8&#8F!<;:&*#9E".!3/'@!>AH#.A8>(!DC!4&/&8<C57#%(/#41=5:B
@r1549
CCTCCACAGAGAAACAATGGCCCCGAAGGTCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACC
+
,>(-<'33F?5(E+B,*F+-/.)G#-B,'28=<441*&=6!+<7E$9F9435<:&D469E-9+'*E:!HG"F/7"
@r1550
AGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCANATTATAAATTTTTATGGTCCGTGGTTGTTCA
+
5%D(->0(G$:'.B$C$+@E(.67727--'3F)=)0%G2':45=!A'.=5!-@":9!D1(5"A>B!!65F;HD&?G6C<@F(0?7(A(D6=<63/3-!CC5G6((9+!.&89"%?E-?*"8+,/13->$$2:4H1')0$>!E8
@r1551
CTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAAC
+
'87=F*E,'-'B@?6!0BB))B2+'<8F4"B$E(2'GAF,";+%8.=*
@r1552
TGTCATGGGCGGTAGACCTCTAAATCGTGCANAGGCTCTGGCGAAGAT
+
@5+?D>4!&(-E#?3G/@:.#320("("B?&;?138*1:3;#8G0=<8
@r1553
CGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGNTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCAT
+
/3F0B$):**F022?,#.$*,5)-*C1318?*=!-5$::*A746A.5F-0.!/$"4-:&BF'"1GHD'-D7?%$G@H(9;/E67D2#6406;0.%E?FB$3!+3FA'!#$C?E:2*?6-6>20F%@">7<%1@=?+*@F%7)D<2BB#'.?4(*D>'+78GD@6%,F;-*%;C4.!!."3)#,!9F*AHB126B)&,7!.,1G2(9@@??!56?,F/<.80/9)7C!46H!?(A$%9?)7;=H?3G3,/;9'"*;A1H=%$-/7'!9:.E4;H,?3+:)D&$&602"+FD09?4:D1
@r1554
ANTTNNTTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTG
+
$!#')&'&%')(%++)*#)#*""($)+&('(('+'*+))'%*%&%*)))
@r1555
TATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCNTGTCAACAATACGGGAGAACANCTGTCCCG
+
:8F-"678,B0$6@=45.A@6E52;=:--A$E</A+<?*%D=?$?!@,@)#8+3D3+.D+1"1:8A252F(C413@9#<C=%5.F+H37G>$F'>?>*$<>6>1G-D=
@r1556
CAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTATACATCTCGTAGATTT
+
@,9,E-*-216@BG>;3'+*%<AB,+/"&D2F$!1H=G.7,%DG%H</)EE.%>F=F!C#$1CC2$H>,=<<$3;.G63#0E.,AA<65A$A;G'3)#FDH
@r1557
TGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTT
+
<58AGF>!@:77(1?7.;0<"7,%6#-"96.7!86*(:;-'#!C8G.'-$*);A>)
@r1558
GAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTA
+
E)@D62+:(9-.H3*8#/8>H#;/2;>4%?2>0F+GE8)+"$/<)268ED,+8F&1#"60>2<&G+H+*"FE'9)F.C$FE#2#37E02A<-(=F/H3B=E.8G/8:!-H'>"$HG9H99B;9A:BA7=4(
@r1559
ACATTTGCACNGCGAGTCTGCCTGTCCTCCACGGGTTCAAAAA
+
D;G@30-<;!+)"+@G05729630+!B-$0%+B8C#)&<.4(1
@r1560
CTTCAGTTCTCTGGCATTTTNGTCGNGCTGGGCTTTGTAGGTACTGGCGTTATCACGGTAATGATTAACAGCCGATGACAGGCAGACGATGATGCAGATAACCAGAGNGGAGATAATCGCGGTGACT
+
7?B(+*=13?7(=5(;!5<?+)2!A4=$.3?;H1=+?'&@(:5:GC.+F%3DA8B1;,&;2->C5(,,(8<3AG=++///=,$0;,,(#>-:30$%5+E2+4."3./(73>&?<F#-@<,583,93/
@r1561
AACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTNTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGTTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACANATCCAGATGGAGTTCTGAGGTCA
+
AC>!=+$.H,).A3/HG>"@.A1%%23+&!.8:98<=AG'!A)CEE5*F?!C3&G(1A%8;#3#2>7F$:&C$D'$B0-<2H*<-7#?697FC++024)G@+*"";-1>."F,63CFCA,+,&4=G/8/+3;"6/%9;C>,6,@##"7*#<!B84'<&G?,/9:42H%1"9A48AF9'H$=A?3*$;<%)*@5,?0-($%$/)B-GGB@57CG01#(+:D>/B0B=++20HHC(5D;C@BED'6GF&'=C7,A($1C=:=D.=G4+.B0B"*5BE+&*
@r1562
NACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAA
+
)("+"%'$#)!"'"+$$$+$"%%&'#"'&+'#%&$%*!+%'%!"*&'(!%("!'())
@r1563
TNACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCCGACCGGATTGCCANTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGAT
+
7)!2G)*D40C@B!-4$1)::@H"G>%0.-21?>,:!7&5/*$E8=!#2:3&,6*2@0+9@#)9?<F5..B.5'#;C.-3,FC!4%*+40!4FCG9033C(+$7;2+6F
@r1564
GGAAGAACTGAACAAGGCACCGAAAGACGGGAAAATCCTGCAGGCGGATTACNACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGC
+
'705#.A?:556)4%F8H0H',<&:<-9@B/--F22':,G!CA62&84+B./7)!1".1>".&!7,6.CD/%?H>2/<+"A.DC:;85<H.<?"G-+-D*9*!66.#',G1'G#6/C3
@r1565
CTTACGTGGCATGCTGGNCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTAT
+
)4?)4A=AC32/..6%F!!.G*FEG'>-.#:</(!=;H*->)5/9E#,G1@=$6/22=5H?$=/.@0>7.$'$F@-85-5/F%+#5-+E??7)%,94>1G/C*1&%*:5@(F7>0":C"6'@
@r1566
NNAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCNAGAATGCCAGCAGGACCGCACTTTGTTA
+
7:+A=0@$*'5##<4,%(:F,$=66G(A-A6!9<<(;CG*C,)6FFG"?;G?G"*1-%E,-5A9H?)31.6"&@"D?+6;
@r1567
ATTNTNCCAANCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCNCATCTTGT
+
(&(")($&#(&$+$&)&$%)%$(')%*%!#!&"+%%))#++$")(#+!*(+'+))#*!#'"')"'*&("&+(*+%%!##())##!!$%&$#
@r1568
TGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAA
+
(C7HG)@<42%8)6+7/,%(8C:H9C%A33+/%A'#;15.#7C0<="%03-'4=1:=?)?:73,-5%+#<9
@r1569
TTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATANG
+
!E5DGA>@0/12D)*A'@+&#<'%%+4$-21G>$@+:+G#3#=!F(EGA'A92-F/.!(1.646CB09CE*<B.4F:?+*$*'!?8?0,+A=%EDC5
@r1570
CGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTANACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAG
+
.F$5:/@+4H>031E;;9A*G'A&%F1.9BG1%E73CB0)3-#8+53/'9&,F*3GB"AA'!5HD-&,C(61509C)(7A.G78+69FG<,))",F/7$%,G+1441@0*;:B0=B$D(:>H02&><$D;E;4B$E96$2-0=/F:.647&;
@r1571
CGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGNTACACCGACAAATGGCAGCGACGCACACACGCCCTGTGGCGTCACCGGGCATGGCGCGCATCTNCCTTTACGGGGATTTACAACGATTTGGT
+
/+A1G039-'6"6@:'!"!)?,*?F)$,%//'261*A1@BB7G@#B-9+:/*-(F;29/>!87D-&<@@.9*);>#=6%,&).C54'.@=$BG+B1839,$HE+GF$AA+%&?->F,$4(&8"/,54$B%@B99+/!@8;.&8B6-9+#6*:$1$H&>10,"<5E(6;2)8#4)34(/-"8&3;G<&,B87H9%C#)9:*D;$#=+/#F=3F?21D(%@4+,452:9;=2(4/&C)@6+@B/@8"(A'EA+318/F@"6#F++E=6E"6(<5(%$7)4;!G$#!<"-D,6.>2AA(
@r1572
TGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCG
+
?,6052*<5/5G58GF#0DEG?-"181C!=40(,+DC10&?8-
@r1573
CGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCANCAGAGTGTTAATCTCCTGCATGGTNTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACC
+
?$$B8H>B0-;B!"C(G,E1815C+"0-!59C,*13?0E'="(1<A+E)/2B:8?$B()+</?-06-='-2D6'+*877)'48&@G8?3?7G2%D>2$%&$C='GG*,5'<!7,$D!B'2AF8!;$$"G3$;5!$'442>"#7;4/E4+1':+F6$G41:?%5)=,47'G8-3+"+*;>B271F&,/-8-1/.?=A$6>31G%?
@r1574
CCGCNTTTTTANNGNNNGCCTCTGCCTTAATCAGCATCTNCTGCGCGGTATCAG
+
&%&'%&)")$!("!!$!*+!#%)$!*&!()#*&'#"#+%(&'*'$$'%&()&')
@r1575
CNNGGANNTTCNTNGACANTTCGCACNTGTGTTAAATGGTTTGCCA
+
$&!!'#$'&&""*&(+$*'%&"'*"%'!"('$*!!%"$*+&("!++
@r1576
NNCCATACTGTTCCTTCAGGCGTTGTTCCGTGGCTTCCCGTTCTGCCTGCCGNTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTTCTGCTGTGCGAATTTATCCGCGTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTT
+
!$)+$'*(!*)"%!!"'#'#'!'!#+#(#"+&$'"'("%')'*$%!%**(%+%''('#%)+"!)#$'!")('*'%)'#'&+"#*)&%!$())#"%!#"!'()!$$&"''*(!"&!$'$%(#!&!%)+$"+*'&##*"+#*$$)%"#('&#$*$$"$#%&%)(*#!!%+**+!#&$(+!#$"&'&*"%*($$#%
@r1577
TTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGC
+
C%+0A,;!7!+?(H&D=EDA-C<&+%94)51%E=2$FH&7AE@)47BF&-,E/11'G(9.;(028$F)BA73;G#*H$50#>)0$F;2"@;C6/"45.AFEG0*$)@-*!(=#2!3E&&9#&/4@9''8E8B*""=0?59.;;<#784+-F7+#9B();
@r1578
GGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGT
+
=88(D9<27'5.!34'=',2HF6B:8G!(3G3;G8+/81-2@07F#*0"%:!<?,(D8
@r1579
CGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGTACACTGAATCATGGCTTTATGANGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCG
+
FB@$)@1/42+941:=E)H)+6(;#'=-;@C+/AC&4@$5@-5)7&68;GD3"9"448G+=;?6"*$-2//D-H=,=7@-9'"60')A/&)6!+3*?90(6%6H"?2D&4"A/A8E<<G7B95<G#9"G>G'DD10;2A'=5'
@r1580
AAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAACGGCGATGACGCATCCTCACGA
+
,4E6=#=78F-2@G"+13G6F?8;4D413C@"$:.&4&G878"4'6$+5)%+D=3)C@!)**6FC-:9(
@r1581
GTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTT
+
/FBB',H>D$'9">,<30>A:5.F,!!!*4F<:<B*C(*G25!$/=/D1$-1#$H'63A@A'A;.3E8*?G6,#@0'?!@/G>#EA1:$D&**!7"FF/<E5@C<57:@A2.B!CC4+;;!.F%5/-EE0.*'#"A%GA6?<3,'6"(030&HC+(%@F6F#5B>:%FG+><:G/8)2<G"(H,E)).68>7C;-"@/FC6!)">CBA''-3#-)=')9-&$.E!=/=/C7E'4&@F.5,%<-7#@)!F-2'+$0-+-'/E;F':F.8:72-)C()*=F@5=D!;G1052."B'@24?<G-4G(E%.@,%>3*>+9G(:1A=""1%<CA$"(1;"!B,6,06B)>D3+:/D<CG=!&='6#0)-$+323F!:-6:;CF+6E9.9/D'(6
@r1582
GNCGTGCTGTATTGTTTCAGGAACAGGATGGAATTAAGTCGTACACCCACAGTGCCAGTNCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAAC
+
>%("*11D-:+0F)H,-0<=)1@/,D=#F2G016(1+/)?FC<9B)20.4H9*B%,*1<:F"(=A@;-(7&D&E3D-B9!%5C":B:(*9/E24C0D'=GBCE14EG8&2@%"5"&+)
@r1583
NTTNGNNAGNGGNTTGCNGGTTTNACCNGGNNTNTNCNNNCC
+
$#!#$$!##$"#!##!""!$$!#"#$#"#$!!"#$$##!#"!
@r1584
TAANAAAGCTCTGAATCAACGGACTGCGATAATCAGTGGTGGTATCCAGAN
+
)+#(&!"$$$(*"&+$!"'%+*"#(+%!$'#%+)(!"(##'!$'%&)"%'#
@r1585
GTTCATTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAG
+
E?24$@++2&G=#<9+4$8EB4:&$$41%27*A?6@H:;--;6$7769@AE>8%(-%/G/4',<G>%8,,H84C,@D.=E";;;12>?$&">=$%>D15%E;#7.
@r1586
TTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACTCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGC
+
2GF4<=E!(3.%-,33121@=35G'<H0(@$C%G1)H/;%48?,#<G4HF+:.C<70$*H#=*D-D'6#&.;+7D(?=-">.0D<-%9(.&*=A&F323-95@D4@%(:$0!A@+3+<A<BCG5%3=..*29=154<:*FF>#AC
@r1587
CAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAANAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTT
+
62>+<@=&57>!';HC#.64A0?,E@B!G?>/=9!>9141/7+2:7.',%$4@!&6B%%$&6"2<A/1#3)H-%*"+1)/EB$>HG(H?1;.%6&(>!&80C%$%BB"
@r1588
AATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCC
+
2H%G0=$?EH)29(E'/D65;"()?3%8-60@2=)6720$E>6C)22A-<:5++E8@-B%9=,'8ED:8:16F':BC<&C&@80,'7A*
@r1589
GGTNACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGT
+
(")"+))"$**""&*!&)#++&"#%&$%!"++)$"(%!#*(#'"#'#)+!)!)&""&")')))'*$)$+*&"+$+$)+""'
@r1590
CGAAGAATGCGACACTGACGGCACTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCG
+
G?*==@C9D99@=1/'<>3BC$*6@D1=G!&)9*FB:8F*<*6B;;'7EAE87C/6&:"62!:%/>4
@r1591
ATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAA
+
9B'.*A*@%8)3E9&:#!7&-E5E&%=#/.B+@:/4*DB5@"1/+/!'(H$3E)7
@r1592
GAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCNAGCCAGGAACTATTGAGTACGAACGCCATNGACTTACGCGTGCGCAGGCCGA
+
6!+:><;>2),AD9H5H!?"%(7+B5+4H8.A%-381!C,#H+B3+&.F/7),25>@60.+H##!,$0?:EA'#";2,01=3"@>6=5*(2+FH)G,';)??"1E,);$/076E/3>;D)>=5.B'(H8E-)@(%/23<+B-:?<77"(FE;3>B'C@!/=#,8(42:#/5-C,=D9:5+/(G>!66+"*<*4A.71@;28D;!60FH
@r1593
TCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCA
+
A(DHG6D>.)#>119&D14>>+1;8=$CA@;8/H="3B6).GG(D*.C7(9%B7,<?<H3D'=D18#"19*)2=1?(@-(+$:,;#CHHH-@'0A10:6EF/E.)@&0,.&"2?G<2232+1>;F*9B#(82(8+2D:&'/-6,"H:05(+!?6=#H
@r1594
CAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGAGGTTTCGC
+
+;<9*D>&*,!!H?H)!/A/>>&12E<@"1(E,(>!>C3>?)0B#EH4:F5?=B$11@9>7
@r1595
ATGATTNGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTNATNTCTGCAAC
+
?%"4$F"<7@'7%$6).C:<C$G3,7;7!?@"&H222844)0;#*H4045;2H+*#3):D+ADF4'E
@r1596
GACCAGACCAGCACCACGCTGATGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTNTGGCCGG
+
3)241+:!(+38:#;/>+?&E@G*:6'8*"%3?<1)1$=A8*C*HE2",G$=32;.FGA20+.H)*"$=!
@r1597
NNNTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCCCTGCTGAGCTGCAC
+
'!#+#)+&!!&!#$$&(#")(#*++((!#!!%%"%'&")+!#$$+)*(#*'%+*#"!)+"#*#"'+'
@r1598
GGTAAAGCGCCACGCTCCTTAATCTGCTGCAATNCCACAGCGTCCTGTCTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAG
+
A!080%050AG61)B-$%/4:B:E=7=%5;$*A;A+*3H@AF>5D#12A+CC@(&A-/59:47%60@6'83:':/=9H'#976>'G9D4B-F1<$+E><&@$1,)8B;A*F&6
@r1599
TGGTGCTGGTCTGGTCAGCAGCAACCGCAACAATGCCAACGGCAGCACCG
+
E344"%'?&.)5H4!GD#*?,B/!!154!6,<3F4?.2'7D$6?CD#GC-
@r1600
NCTTCATGGAATATTTNTATGCCGACTCTANATCTATACCTTCATCTACATAAACACCTTCG
+
'+*+!$$"(!"%"'(#*#'&%%*'###*%$(*('+))&$'!!+!&&&"*!&!"$+(&("%"+
@r1601
TTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGT
+
?$.A(&1/F98)13"?&*8G8C50F&92$D4>B4(*<3"2#'F,;5#.92DE)EC2%2(@C$",;FG
@r1602
AACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAANAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGC
+
)+#('&"&$+'+*!#("!")*"''$&*#**$%(%)+$*'*(%%"$%'*%"!%%(&&*$$%((*$%*++%+&)&)#($)&'$%%%+#!!!#(($(+&&(+)'%())"'
@r1603
GCTGCGGCCAGAATGCGGCNGGCCGTTTTCACGGNCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCC
+
=E86(#=+61)83?:-6$1'F3/.4!7,!=&)8%)2)(<E39#3>'1#D1A=F/*A.:75@9C#4A90@"!!B2,!.*'9.(0#10(
@r1604
TCCTTGAAGACGGAAACCAGTTTCTTGTTGTTCGCNATCCTGGGAGACTCCNGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTG
+
?EE4E;.'&.8#/27649(1$=4B/>B*(DDF2.$F.#A/;H9G&C/8HC6;*E9;;?-7(66ED*H(>##?9".?A*7;*@B'(GCH#(#"=60)*3('4+<+:0(/.'&18E3>HG#58GE+F?7/:52=@(:-=7C$$EEFC9.CE;>#),:722
@r1605
TAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTC
+
8B/>1D@('9@/?CBG";82#B14/;,F>2+23$+6G?-#G@C!0-93H*9D,#A
@r1606
GAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCNCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATT
+
18B#+63&3"7&:#'?=%+>,HH$7211%?$";?F:,,+D*,GG*65<1(0G)"$1+5<.H4$F$+?'F,>5F1$;%!EG@1'5
@r1607
CTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGNC
+
/&3$)<2*%%-6/B,3&H"@5)'H5H7,/,8#"-?!!A,5(!(9(%591"'C?@B;79:78FC7-+/6)=F@6/')9>,DD(9C#;(9E00F.7(-.$829,B?=
@r1608
GNACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCA
+
/<A7#)G-C">=6/EEF/FAF84F(!(<)).4.',B,3?+9G;@3/:+<-1
@r1609
NCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCANGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCACTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCT
+
#+%""####!!!$$+(!")*%$"$(**("""##)#'$*'!$)!*+%*)*&%)"+)+$!"+#!!'*+$##$&$)")+"#&)"!!$)*+#"#&*)"$)"('&$)+&!!)!+*%+)&)&&&&*+&"#)'!)*+%)'!'"$$&!%)&&+*$#!%+!*%&$)%!(!*#!$*#*"&'"$)$+!*()"'(*"+'*'!!!#!&++$##&&*(#+#*'#+&*+(!!+&%%&+!"%&"$)#!&(++&+'&"!**!#
@r1610
GCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGNANTCAGGATTGCAATCANGGTTCCTGCA
+
@(BD0?9>%"*9><3:&B41,E0452:-=)2*=3FD8?,AH*%6/B$@-'+$2<>F88+1*9+*F$+@A40.H?@"(>H5/4?//"H@$(B(538$H'E9)9@E8)<07C86&!/;98(5!)%:&%)6."B*7H&+.48/%.%!D*$">8:=7EF>*D>/8D3?BD,2*1-DAF;#CE=BE?AC
@r1611
ANGCCNGANTGNANCNATAAAAACGATAATGCAANCTACGCGCCCTCGTATCACATGGAAGGTTTNACCAATGNCTCAGGTTGCCATTTTTAAA
+
%%%**%$$"*($'$&%+'!%+"!!%!$(%#+"$%+!+(+))"$(+)()%%&!!$*!!!)%+('()%'!(!&%+(&(%#*$$&)!%&!('&+)!*
@r1612
CAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCACGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGC
+
;2*%;":)E.@D/*<F)*%E'+=+D+*18<">'D2<,AE5=1$=GA*8"3B0?BA$;09%41;)36D6$8G9HE"3F4/#AF:>4<-.3',D-/F(CCA;B%1#9"1%7,+,979(F"8"-(#()3.$9G2F#,(.G$G22B%<69D%%.)?)<FD%.@G:3/B1A
@r1613
CGTAGNGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTG
+
#)(*(#+!&((&%$)&)*#%%'$#)#($$()$#!&($%%')!$$("($)*+*$!"$$&**+(!*&$+*&$!$)''&($+!#$!&+'!+#+
@r1614
AACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGT
+
3</3A8C(+F9:'D$;C5E#56D>,FEF*%&!FH('4=";G/.H%FH6E3FG0F:"+FB(!B<A)'CB<-2><7);(B#&5>8D$@CB1,(F6</0F05371>CE5
@r1615
GCAATCACCAACCCAGAAAACAATGAATNTTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTNAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTG
+
@>+CA3:!%=((A20#):BG3/!3ABA?E359*C2B7D?#9C/>G:/F6'D)?21#EF?@6!7;;$.(!G:6!A$'1F0"0*8D@B(05:-)"E.6%*!/C;!.;?=8B634!79$D,-2!@D&,>EC(@/A9:/FA>7;='G5)9)/!EA+(9;!9?10-/"AB7/5./B8F+#7*.9)<DE5/3)7(1>*%(*>
@r1616
CGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCA
+
C5E>G"<DD//89.#@#C%DDF!%"E8F%,A!B561&60!E;>8C03,9.CCEG#=9,*<4F1/F&A&&0.'%B6=620D#2E4@F@*,()@F?>)>=-*<1.B@7D58/$5'GH4"('&!,!H)+A1'#C
@r1617
TGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTATCGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGG
+
&53573$!#19>%50A2)#.AB:/)?.4A.&0"/$*+--=9>.3,9E-@>&;@"-*",5:%<-6"*#1'%#$#"/?;D4H(3*B&1&9@-46?:-#>9D)"9?$G7$$AG)$?
@r1618
CGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTNCNTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGNAAAAATTNTCAAAGTNAGCGTTGAAGTCTGAATTTAGCCCTTCAATCNCCANAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCAC
+
+GE=2/+*=4>4-D<=118<;"0$0)$0./BF*0%C)G7/>1E*$+)D/-:6<EFG;?-H&8,<&)A/F+/=@HB,?16)(?+=?3H'>&9.*5E/*-?F90?!;A,#/')>&G=:->1/&)E))8)9)C;?7AHG96,H)F'1$98*3),BH&=@>"->+@'97*3#!9;-$68,189A(#;B:>H#/?(#976F@$9;7?!*08C'<:$:BG;7/6'D-.G><&"=2!'=&3FD#$GEGF<"6.??<2)
@r1619
GCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTNGCTCCT
+
=*A5@7$?"&@80:;A>1G=A2H=)0+=$#2)>*1G3#B?-%0$D13,;3'(,*C"2D4>:G*48)E5)<$'170?!1>1&;'
@r1620
TCAGCAAGATATCTGATTCCAGGCTTTGGCTCTAGCCGTTTNGGTTCATCAGCTCTGAT
+
@/>%C=?!>GHF'&4=A)?'?$H:19-+;>G%6993E'292E.E=%:H8?*64B/$&-7
@r1621
TTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAA
+
C!<!?%!"D?(=+A%@4-H:*EBFHA:5@:9>6@?99$4>F@?A-55@E=;DA25@F76>.C!75;,0/DF=')1D1*:53??5-1@
@r1622
AGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATGTCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGAGCCTTTGCCATTCAGTTCAAAACNGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGATGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGC
+
+""!!!%*''%'!+'**("!"(#&)"*%)&)$'%&*&)'+%(&$+%'$&+)!*($%&(+*('+'&(#")&#+$"&(+*%()#"*!*%$%%"!'+(%#)&$"%$)%'$"&#&!(#+')*'*+#$(")+)$#!*!!(&$$*))+&$&*#)($())''$$%++&'))&'')'''%"$*!"(!(!%*&*!'&'"*$"&%+*!(+#%')()&)+%!"((((*#(!"%!'+$*$%(+'()$("!')))%+'+(()(#"'"*&&"!!"&)'&(*%$*()"*%$(+)*
@r1623
CAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGCTGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACGTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCC
+
7>&>??+22CD;9!<:5C!;C1>-,%!H8'<)*6CD%');$)4*=::8D05!0%C/HF8-%=5&@F%3@2G5+;=<#>A%>3#(13D/,G:)+.:)64.C-H221E!+1=G*!8CB5)BH61>=;>/$(A+*>-D$/F!$B050).9@3)1=487##D6*G&62$"56C41AG@..!#7C3=68'95%942$%11*-&EE7@!&?!<1;#"$F-E;)497'77@*2*(
@r1624
TNACNTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTNAATTCGCTCGTTGTGGTAGT
+
2>5E#-#$=G,>,4!1327,=.@>B*+F:@5-!'G.$/0.',<2-D<?9GG,%3/6:-A/$"D#?
@r1625
GCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTG
+
F?*,3-4-4G<''D1;/!20E;:1!1CA'%*0>+E3HF6&/?DG2;/F1")E=G'/C2>>/F7C'.C56G3AABG908<A<H?"*=$+8-+37!<FA%,@/5!))<H'/!3,%!?#!E=.:.0=%GE5)7""67#==0E<%?F8=3%
@r1626
TGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGA
+
8@#?<)*G3,C):/.64>D(%#,0@:82'2:FA$,/C6!1A&,"0/38</9&5(0*##2=-?B=0&4C0D--9*.7#A"5.'9F2:+;4B(@C8#/:(?G5+;?+4-?E5G<.A5@4C58A<:A00.'0HD:%5:ED57?4>4HB2A&21
@r1627
TTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACTTATAGTAACCCTTAATTTTATTAA
+
G<A(35G:G?HG@=#G,1C119A@"*0H953C8*0#?$((,'6+DA:&><&D$8!%)+%25<B&#'@GD'+$E(@%=9*
@r1628
TTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGC
+
?GA&H@'F57F+()$C-3G<2"6%)>A/#?7(::<?A?C&8=$8==132=64.%G*5/"B2/&E/,B0ECE7B520(17D:8>4,2&B357
@r1629
GGGCCCGGCGTCCTCTGTCTGTGCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTAC
+
;E4.5/H.9:%$C>CE@5.9A.*(("EA22)+A=<-<H*&%"23'7%D93EG%*&?@.7E4&#-5A(90(
@r1630
NGTGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGTGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGC
+
"9C2A5!0&?B1F=D@08$9+FF=6-1(EFG-!8;A(-->9(C-9@D-3G;G7#>H#5"194),?<80B9-G1(F7+#$+!2))#E/3E?H?&46F1:,80:"C"'3<!<B,0938EF7DDA)$/</A9.!2EH?D#/#",0!'!9;#"*:.5+4D).+'A--*7?H@3E%8<B/1<67D7":'4
@r1631
GGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAA
+
F8B?6(&A%<,D2B0*B49ADABB(5=%2*"<2AF38,')G>D*H4/=-.0H=>15312G
@r1632
CNNACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGNTGGGCCGGAGGCTA
+
&!+%)!!")*#*!''&%+(!&))*)))*&*!#+&&*(++$'')*&+%'#'+&*($#($%)$&)+*(("+%'+"$'""*+!!+)*((#!++'))+!%*(!%(#+(!""$%&*$$#'&"%%!)!'+%'!*+('*!)%)&&#)$%++()$)+%&%!*%)$")+"'+)'$#$'$%)!&)++%%"*$)(*(!('&+%'!%*'$("$(+)"(++'&*"$)&#($&$$)+%)($('#+(!)'!#$)$'+'&&"%*++$&+&##&
@r1633
ACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGAC
+
G0*%%#C54!F-A/2$CA37G!B9E>H?A;%F./'<(EB?EE)=9@:F1!9;F,*<
@r1634
NACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACC
+
$>'%1C;H1>:G@!B'D/0/CH;4/-1+++,1$D+%6A-B<?08',AH:#"
@r1635
GGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCG
+
4?0'E3;-3C:'3,6G+;(@16#5G:C,#F,13)"94C?='C@#H;
@r1636
GCGAAATAGCANAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATACCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGAC
+
A#@2<(1!=A2.35<;G3F,&-$/=D&;D#;#>8<GD'&E=-@3.E8=637=)5;/D3,0'#5>+.,!*3G/FH+;%-.+954B*6'@0B0:5D2EE8E-
@r1637
GGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATNTCTGC
+
2E*C2,74/1;.64A>(54E-A(/"82,@+-82,9:2B3":./..*2+G+":@&AD(F!$">89%93318
@r1638
TTACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGA
+
)$(F*%-B'>=G%'"0/-H=,+(EA,&9E<>E6'D-%.G:6;)>!&$5-?8%)7."((9GF#>1&$2.%A'BC47=
@r1639
CCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTA
+
@1,66A2G!)E)G?,55D76(H=G!B")%#&#B2=1.'@36>C)7*&<71:7.G39"G'F<3$>'C%?#'@5+8/0AH'?@)$F$+#H/?@6#0%-&A;!@C;$30+893/'>!A0C,8A$60A
@r1640
TATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATANCGGTTGCA
+
F.%:&$DH-(0G92'-;-+>>22D#"?/11+$(6H=?C=$>?"7D8$B0F6,%F.'=0'(9);9H.</;&;4'
@r1641
AGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTT
+
8>D4@2#33!GEE*5*F>'#=3*>5?AEE+65/4@D&,:;#8A!8;86A$77D-2-6<591H@/B>+$=/7"(:@4.(-'C*=524"*@$<+#5,(&'!%37H:3-
@r1642
TGATTGCCANGGATGGCATATTAACGGCATGATGTTGACTTATTGAATACAATTGNGTAAATTTGACTCAACGATGGGTTAATTCNCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGC
+
*03A)<)@59?9/%D=5"E,1E$;B&E)?4&B(B)FEGH;G@0D'F'<4=G&1!$7;>;%'#*?@:8G@$0?>;=#1F6&@BB%#9C1':/-';&E9"96160'#H14A%.-77!D):=6(9.'EG1E480G9B!2
@r1643
TACCGGCATAGTCATCATCGCAGATTTCAATNACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCCGCAGTTCTGTTTTAATCAGCCACAGCCCNGCGCGGTGTGCCT
+
AA26$F'#G,@$(B$<@.?=?!F$E''(9).F%C&6=G&".H*&=%BA=D&"GG&,:@%."D&,&697<F'%$35>C-6B9':HB@7;>:1<D-3H4#"<0+3D#420:>;G'5,=8;B&9/";8%!<(0;9-8!:H#
@r1644
TTANTTGACTATACAGCCAAGCCTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCA
+
:>++$012366@#>:="')91,A33695</"%+AD0$7$7B";C!22#H0H&(E6D$0)0GE
@r1645
CGGATATGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCNTAAACNATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCC
+
)?4E(4%"B+(5(-GFE'%;B.1<5"2/H7F17DA1-AG&G(9?3E?"3F)DB",)D#($$"E67B#;;1%;3%7<3C-4=3#+8*'53G6+#=3D#/)86@"2"+G1$%1H,A?+-EG$,2-50<B=$0H$
@r1646
TNNTTCCTNCAAGCTTTGCCACACCACGGTATTTCCCCGA
+
$!':'$/")9&47)C!%6B@77(.+%'.@!E%0"7!$AF7
@r1647
CTTCATTAGACCACGCCAGCAGCGCCTGCTNCCCCTGCTCTCCGG
+
2)&,$G&$!-96GC@3*7"-7@H-E<F5>F@-@,-8$E7;F-<+&
@r1648
GCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAGATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTG
+
:H3E:F=E@E;F,.=2!+'1#36C300'1?#F,#,-1E%AF>B-.*>8*<H2@F(F(>4>40/4D+DE!0!G0=4?*,0>E9BC2/$*!9F@8==7'#A(@?7$#CB:117,)AF-335!8$F/:#),)E063/&:882-DGA!)3$=F!)(@<5*.>:.5+G.BBF7-66;E?E1),(*5#9.<H9<$<)1<%.+@:@%!>-%
@r1649
GAACTTATCAGTATACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAG
+
#$BHF%"'+4*A?C#-)#G88G(H.*$=.G5;)$2%D=7(0;-,2&,'G%
@r1650
GAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCNGCAAAGACAGAAACGGCAATACACACATTACGCATCG
+
#E,G"$8)0F@.")#B#$=H.2"0+.7:+5=7!"/.5@"2<,H(=$=&=#-3;)!18!A9C=<80B(9'*@;-!8>G9:8?D(F:%7<$?$'+:&H&A(!#&1@<'EH
@r1651
GCCAANACATANAGTTANCTGCTTGATTTTCAAATGNTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGNTTCTGCAAGCTNNGCTGTATAGTCAACTNACTCTTCTGTCGAAGTGATATTTNTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGNCGAATGATATTGGCG
+
"'*%*!)#()#"%!$(&%)'+&#&(+#!*%'"(%&&$+!()%+$%'#'*!*#"$"%(*(*$%!''()"!%#!%*%#&$!*#'*)#)+#'$#(+*$*%*#*+"&")'"*('(+"*$%($)'$&"'""*&%))""(+'$!+$'(&'*$*%&&#+"!(*(!'$%$%++'#!$'+#%(+"**!$*")%)*)#!)$!+!$)(()))%'**%%"*+'*+)!&%"*&+*"&'"(&$!)*'')%%'()+*+%!#'+)&+)(+%)*)%&+#++!#%&("$)'"(+%&!'!)&*$"**#&++''$++#)'!#+%*#")'!!$$*+%))!%($#)$#""('$"$!%)
@r1652
NCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTNATCGAATAAAACTAATGACTTTTCGCCAACGCCATCTACTAATCTTGTGATAGTATATAAAACAATTNCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATA
+
$&+#)%)"!"'+'$(+!+)*))&)&&)'&*('(#"$%*#"%'+(!&$)$!+"$+'')"%&(+&"!&+#("&""'$#*+!"'$#$#%+)"(($%%'&)+(*)$#(+!(*#)"'"'(&')('"&+$#&)&""+#"%%#)(*%&*))"(+&++&%+)
@r1653
GCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTTATTTAGAAACAGGCGCTGGGCATCAGCGTGGTCTGA
+
6>FE$<<A%>5991(->6*0H(A8(C@@50)B"BD#A,<ED>?%5+6A>":>6&D=,H6A&EH@:+=+1C=82=3:=!H%=F7(.C",//9:/1C#=,79;/0)8B+>?.1>A59/,?%=879F%2=EB24=8F)9E"
@r1654
TGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTC
+
2:,4!'+)%04$@0>%35=)0)(!!A/(GC2#H?$A%((GGG)6=B3>B>-:.8D;H,,E6,+4?:+-'HB%E5DD//4-(9CEC!*G"A(A+?+D3/.C-A@:!4B*&-
@r1655
GTCGCCTTCGTGGATGCCGTTGACGCNCTCCCCGCCGCCGCTGTTTTTGCGTCTGCCNCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGANGACCTGGCATTTGTCTCGGACG
+
$0EHC$G'(+03:BB1:AGC@GG!$=?)%C?45!G%**C>3+2$&CG&B!1.E9>2&HA8,75%:.G"1H/.%(+7<7EH4C9%1B/5B!C1@$>".$(H#F>+0;3HH@E)9$)
@r1656
ACNNCNTNATNNNTTTTCTNNTCNNNGGCNTCNNGNNNTNCCTGNTANTNAATNTCGNGAANTTNNAANNNNNCANGNNANNTNNNTGNGCANGNTGNNNNTNNGNANNNNNNNNNAGNNTCNNNTGNTNNGATAGAAGT
+
!##"$#""$#""!##!""#"#"$"#$!#"!#"!"""!"$""$"##$"$$$#"$$#$#$""#$##"#"###$#"!#!!"$!""!!"!!$"!##"$"!!!$$""$"#$#!!!$#""#!#!#"!#"#!!!"#""!$#"$#"##
@r1657
GTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTG
+
F<#&<"6*D5?$232>#A3G3&CE9-.C!"?>(1(';F,*<&1%H'08")3%E?,F4/*B*8)4,*3
@r1658
GTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACTTGTTAGCAGAGCCAAGCCACAACTCTA
+
B.+;.H*$>>,#B1!:"A$:5-#*B/#.A24H>DA2+<*,+,CH9F7&@-'4=):2FC$+6'04968E&)?2<BG?3,
@r1659
CCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTGTAACTATAA
+
H'B5#?*4C*@$338G9&7%(5/7DD#%7>+&39G#6H6,H+8(6D=330.1G%%7!)4G.&0A-3459>-07=.0C#93FG%,:C$6F.:8E@6BF!3B%,5.-9*',H?@7>
@r1660
ACAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGG
+
(+&%(*!'!%)!''("!'*')#!$!('&%*&!$$*#"&"$'(#"('+!')
@r1661
ATNTANAGANCATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAANCACGATAATAATANGAAGGATTATTCCCTG
+
&%%(*+"!&&%++%++!+++&%('(&+)**'#"%*)*!)"!!%#""%*()*+!%&"*#!%!&)!%'&#()&*$"!!$#+&"$"#"!*))()
@r1662
TTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTNCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCANTTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTG
+
F43(@F4+,>?..9G)G-;%C4=5BD;G#!83$-6##>B,75%5C@?C*A:/"3.)8?-@<.C<F;:;D%?HH2<%1E<@'''>;@'!)#:-A*"HH,(E1/53';>",9AA$3B):=,,!9.G5-985@A2,;4"2D-8D-<0;;//=@F&8/*,D8:03*F4A22?!H<2-
@r1663
GCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGA
+
+'!#'#+%'%*(&**%!!&%+)(+&&%!"$&)%&"""%#('!"!"+'!$
@r1664
TTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTNCGGGATTTTTTATAT
+
401'62()E1,!.,;=.'&48*'%%$.#&9985DC-C!:?->7&/&+9?"
@r1665
GNNNATNCNGNGNAAGAGGTGATCAGCCGCTGGNGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTATTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGCCCTATCGCGGTGACGACTGCGGTTATAGC
+
*&$")*$)!()(")*%$$++''##)'&)+%&!#)$!"+!"$*(#+$%**('+(*&*$%%(&()$&'*'%'($!#$#$"&*"%&$$'%$*)*"&$!"!)()!#)%*#+*#$(%"&%*"""+!#"'#&+"#+$*&#!!*##+$"*)&%&(#*"+(%+$%))#(*%#%&%##'"%*))%&%*#"
@r1666
TCATTATGACAAATACAGCAAAAATACTCAANTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTAC
+
?<E>.FG'*16AH6%*9D#$;29/?4?B26*=)09.*8''1;8394$&=#</65E-B!?"GB714D&H(8G%+BEDFF&09=@H92"'&?E(
@r1667
ACTCTGCCNCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTNAGAACGAAAAGCTGCGCCGGGAGGT
+
"'#'*(!(&$+"*(*+#)'*)')#%!&)#&$#+'%'#)*'!('+'$"*++""'*%((%!%&+'($'#)'$#)#
@r1668
AGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGAT
+
+#'+''%!")$'&$#*#%"#)(*!)%'(##")&&*+"()&*!!
@r1669
CATAATTCAATCCANTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCT
+
440D7-#E;7'<@)E(")?'(<D)*?6??80B&%6%H.5>1>",1'>H9=35;+B1CG-)+D>$8'6DH-B/9C!4(2,G("#70!D1=$5H?7F0$95(B;+)$H!HH
@r1670
CNCGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATTAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCT
+
!!+&$'*%')#"")"*#%*#&"'$'(""&+#"#)'+)#$##"&+$&*$*#%(*%!''$*("*$%(%'$"#'+**")+"'!&*$++"'!!*$#$"*!*%)%'
@r1671
TNAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTT
+
$$)G2G<D:D(8=//06545?1'6?F%+<9!8(=/%4;D/
@r1672
ACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCT
+
$$D<>>>138'-@=9';?+'/D+-(+;)@##'>0G%/7,6!!?A
@r1673
NNCANCNNNCNGGCCATTCAAAATTGTTGTTNTACCAGACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGNGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATT
+
&#$("'#$#("$#+'!*)"!!(*()(&&((&)##""$*'#++*#%+$*$!&%#!'*$)!+*')+(!$+)#*+'*)*&(###$#%"*$)#$"')(%'(%!!$$(#$**%()*(#*&))$!$%"$(("#&(%)$)$))#"*!+''(#+''$*'$"*"&!#%%(#%)(+"!%%'+(&+%"'(#*%!+(*%)*!*"(*&!)$()''+''!*)+))
@r1674
GACACTACAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGT
+
%20EF%(?F%3*,CE6F=?$7D6H@7H:4.4210<#C,=09>G"2$?1&E%!30?F4H:3<$4H.$
@r1675
GTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGC
+
GD8-BH(:)%?H4=B#?0'H<96"6AB$:B3'?2)E/%B3)+H#$3%AA<DA"9A:G?4"5.114!7383$)=H%"!E8GB.,.F'7.F
@r1676
ACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTAC
+
C:9(A!C?.=19>%@.C-("%;H1<?;C"4,."G4&8.'D.<(.A);B@">0$$2/.GEH-;#3F!GC'(C.20299H8B7H
@r1677
AGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATNCGGAACTGTGTCCGGAAAAGCCGCGACGAACNGGTATCCCAGGTGGCCNGAACGAACAGTTCACCGTTAAAT
+
-%F@$/,/)%*74=$;@0+)'$6AC9:A$?(:>H49)9H"F6<4*3D"#@)5"BC>,@)56";/$E=%2A.A@879&7":3+4,<$GFE)2.A%?0";/E>6/%DCAA-1@F5.""F8;60C9)!+=">?='/4G5.*>2?8C(?5#);#31H53@6--".4>#.**E
@r1678
GTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGNCTCTGGCATC
+
;(H"5=!">G6!";+A4<,5'!42*F7504G#F&1*?7"G9!D6F<BFD@$$+;#BD33:G#4%#:540$><%3/366#&H
@r1679
GATGGCTTNCCTGGGGTTCGCCTCGTCGAAAAAGAGCAGCA
+
<F0;DHB5??2;G+&B;+/!/$'D?C'>0A:*5.%8H(*?-
@r1680
TAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTT
+
>D%A#$;C,(8@B//>B@H(1*#149D,))*30&C-7!B<FG-(>EFE7.(@8,,&%#0,G)8+CH24BF"72:@B,#"0#<AC+@EG+=&E)+4:/G/7H7$4"C/"D>A#@'9+)44="?&/6+$-C)-908/DF
@r1681
GCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAA
+
A9H.0.(*/"A"84@=2G=$-+...2$3C8"0=$?@B-5,892:(='-)F0@>%H&6F9!0DE!=D>*6E3523@#&@?>9,*<:7-,/=62"85
@r1682
NGTCCACATTCAAANGCNTNAGNTGNGGGGATTCACTGGCTGCACGCTCAATCT
+
!%!)$%%)%"($&&&**$)#'#%%*'+!'(!'"$!')$)&"+$")!%)'#('!"
@r1683
NNATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTG
+
!*+E/(GH3*G)&)F0!GB%B.<#FA.(</>:+@=2EED=$2%
@r1684
AGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCNCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGA
+
%?8H&><5,?*/>?@.(3/)3DH(C?CH0#,'''#@138#@@9A1CAE'9HG3D8C,3.DE$'8G2=@1@=EH+&6#*7'!@)<7<096+C+)#650%?">$3@/6+-??
@r1685
CGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAA
+
&*862+-%2F9"@G@%E3/(/287?;97$1D;;#6"F&C,6A"!"$<+53DHFC5>*35
@r1686
GTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCNG
+
A(7;A7987,&!%@:+7"G%.H8H1#2":1&1">1FA,:2'!6B<,#-F'G5?F884;"=634EC%4H4>**B&#
@r1687
GNNGGTGATGNCTNTNCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAA
+
"$!'''*"(%"**#(!(+))((#*&'&'%)&(&*'&$)$$!*)+$!)(*)++(#%
@r1688
GTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGAC
+
*.@*'+$<:!(8.B+,""&?=0,+?@G?C9"2871F4?0%77">B&/B"9E1
@r1689
TATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAG
+
.#:6>4C/$$)&?BF@?B/'0;;"@"+7A$@@0!2D/B&(G(H4.8/B!H&97?4*C&0F1.*:,A)AA(%/A&
@r1690
ATCGCTTGGTGTACCTCNTCTCCTGCGAAAACTTGACCTTTCTCTCCCANATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCC
+
5%B>&#>3$.)5==EB#4%(-(6$6C/4+&.1=-/D6-=EC":;')6-%C#B9%*3-0=<F<$>(%38G%;(3;>($'*<%E!4>4%!-)&0-F2&:3',%;E'34%7.:%2&":*!+"&)'CD;7=>+@,9HC,G33C2>@36(('?$
@r1691
GNNNCAGGCAANNANNNNCNNANCTNNGTCNCNTNCGGNCNGCNANGNNCNNNGACTGGTNCCGTAGNGCANNTNNNNNAANGTNNNGCTGTGNCGGNCATGCCNNNANTNNGNNNN
+
$!#""#"#$$!"!$!##""#"!"!$!##!#""$$!#!#"!##$!##$$"$#!!!$$##!!#"##$##!#"!!#$!$$$!!$!!$#!"!$!"$$$##$$#$$#"""""$!#"!#!!$!
@r1692
NGAGCTCTTCATCATTTCAAGCTATTAAACATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAACATCNACAGTCAGAAT
+
!*+9*0<E*<):E"(84<;/)5%A,+@0E1**#6(0D"6!8/#"A,>-*=4.C5/E16A8+,G(<*4D755E(;F"@E<0C"H#5*F.--)!+36!ECA.C8H@H7>2(GBD,&H3=?!%B()*>)925)!950G$.'+C&.":%8%3+>%;"A>$-
@r1693
CCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGC
+
9.(!9#D5:-8+'*6D1+64.=>A9CD8C1'5(/&G+?@9#%(>3$@B&<=B--/%)*;$'=53H/206?:'C$B.$,@E?#-&+&*,#>:F0%>*=5F@"2'(&(C1">/0$.@",
@r1694
AGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTNTGTANCT
+
+*(#*'+"#%"#'(#!$#*#'&!"##*(!##&%"+(#!%)%&&'*$)&*&"&'%%*&$*%
@r1695
TTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGC
+
-,9G?:86A<A/$).&G?#H/:>'HB09"2"6.<D$@3&:-+H*6!+F!&@04>6&1E#9?0A'G:+8/.4:$'#79>926+,-&6ED8&2-CFG7,#.&H#=(;!4<DG3,!*7.,(9G=(:)@.$'4D"9'?F'>2.H0AC<:H&$7'H1H,
@r1696
CGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTANCAGGCATTTTTTCGCGTCACCCAC
+
=@B7F@9=2E2D91AH"=<@!"-"+D'76:>AE?(@:B2>+."1CH8;(-/>'H,F/>;B=%.!A4A,..&D<E"?=(-@:!)/G81
@r1697
ATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCG
+
2=$4FH%A%H<%@8A+9G($'%!)HH78(%8/7HD,75$#/8D/
@r1698
AGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGC
+
DDEG3D8$)006D.61*%;-4<).$B2<=A1#"/-,A'D1'2&/.<"&;1760+..>&7*G+$2H2:-''-B3!/7863F--8'9EH76$$2?:$>(EA*D.(*,A=
@r1699
TTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGNTCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATNGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGT
+
4:(;7F0".;44317>->H?/<"5!FF+"+$)'>C:GH86;(89)1$B&-<#/$)D4=C<$%F@:D3A*49C(%GFCE,DC;":4:,9?;A'':)E+A@,>93!&?@-.,@@535$G2<8-!(71'5+%<-".H4*</E$<CA($#'?/##C#!@5)"+$//@:102#
@r1700
GGGCTAAATTCAGACTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGANGCCATNAAATAAAGCACCAACGCCTGACTG
+
#>#1-..<1%%*"-;'>=4%(9@#B<94@1.!1D,"(05?(,045GG:;3/*#0CB8G6-@;=$@$/A$%>:48!6$!G32AG/#F80&=76G$2E(:;"70<64E#?
@r1701
NACTAGGTGGCCTTTTGAAGAGGCTCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCC
+
*&!"+$!+*%!)!(%*$&!$!*(%+$&(*(&$(%*%#""%"%#&$+'!'#($($*!&++"##%"$!%)&
@r1702
ACTCGAACGAGTCGTGGGCGTGCTTTATGGGGCGGNGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAA
+
$"''+'($%%+!"&!%"'()#')#")%$'$$''"#$%#+&+("#(#%"#)#")(%$*#%&'(+(!+%%$#$!'*%!*$%&&$!(!)(%"
@r1703
TACNGACGTCNGATCGCCNTGCGGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCC
+
)&'$(#*$!&$'(')))$$'(%)+$%!+'*("'($!!&!&!%!&$("&"'+&")#*#&"*##%)(!!$"*'+!)%%+*"*!%#'+$*)(($'"%'!(*"$((++&+('&!"!!)$+%!*!(&$##)'++#$(!!(#''"*%)
@r1704
TGCGTCTGCCGCGGCAGAGGCGCTCNGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCAGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACC
+
A*EB+A57+H&9-7'6,""-5."38;0?9F?9@!<AH.(&*F62D84B+77?8G6>2*"*+8C1*6(@$H&@3351DH;("8'0<8@"25/1@',+;&)*%,91'><+?C.6E'(6+2%>-,+>F/%B3<1A@=14)7@";/-?:G*0/5&9.=GD=@4"8.;8")4;3=./&(37DG
@r1705
GCAGGTGTTGGCCCATGATACGTCCCGGAAANACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGNGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGC
+
)7".*';=G+"#F&78-F89!0>+,$):/+D!3@A0)5@<<82HE,'6BG3H=.#6A%9:/?.<+9(/212.H%CH.%HE(%7/E"&6..%$B&;<9+5;(8EE;<E$,G9-,,+(,
@r1706
TTTCGTCGCGATAGATGANNGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCG
+
8(4;&,./77)>&3#9)'B4/0-3)CH4?=;2F:2C&?/@1AF(EF8:57FE0=@DH'-&*F!)&,F"D93GD("F33)3D8!H5B'C/?##,)!F)2E/H;H(34/+#4
@r1707
NNGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACNAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAA
+
%#627'E=128&5<#'5E.A8A>,0DHG/5>6&(#7B5E$&.)61GD>%$8(@CB&5!"='(=@BG:F$;9G96*99D(-5.#4G(<)<+-,#E/
@r1708
CACGGACTTTGCCCGCCTGCAAGCTNCGTGGCCACGTNGGTGAAC
+
('7*.*",0!F1*30-%-23:5:%9A8H3HE8(89.H!-<&0&#E
@r1709
CTGCGCGAATATACCGGTTATCACGGCGGTGGCAGCGGACTTGGAGGGCAGTTGCGGTCGTGGGACCCACCGAGTGAAAGTGTGGATGCAGC
+
)D*"0#.F+*D,/-<G'B'D=37;=*A0DB,*1&B+#CA+CE'D?00);H8&>!*/2D*B"/.-204)/*6.$$85,?&0C>*:HB6(=/'(
@r1710
CGTTACTGGNATGATCGTGAAAAGGCCCGGCTTGCGCTTGAAGCCG
+
,5'G&$#@$#A0D4C@*#=8'8%$G.@0H7H%.8/373:#B*'(F'
@r1711
ACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCTATGG
+
-<,FE)/)"!1HC!D,-8(71;BCH<.55,!;;7%12E2..2B%=B&&1"4@-%41$===98/C;@#)
@r1712
AGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTNCGA
+
,6.())%6*!?1$-?>:$2B0,>GG!'!.#?B:.GHD/=74B@=
@r1713
GTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCNATCAAGTGCGAAAAGATTTAGACTGTGAATGCCNGAAAGGCCGAATTCT
+
&+!"$*)$#"$&+')&%&&+!#%%*+*%"*##%+$'&!&$('**%($++$++"+&%'!$!"(''*#&&(#'"%#%($+%+"%'$"%)!#!&*
@r1714
TGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTNAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTANCAGAACATTATCTATCAGNAA
+
79!+-9$+$)+6G/;6,5<<D='103D=5HB%69/G&.1760C!"(70:*C'%:F%%)B=HG!592'&D,31+(F0G7;,=05C$7-"/#)7?G<H8>;B/87G3'''?9#<70%-<>#81)(&C"E6=$:G7&?.,B6!?A/79F;=43
@r1715
ACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTC
+
+&(!%)&))(+"&+!&(+*%&%%*"%!'(()+)(*%(+)!+"(&*#(&(""'!(($)#+$"*%'%)
@r1716
GATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGAACGGGTGCAN
+
)73,6(?"$2F@'E..->)@C%1;5D.-&0;C4-GG;4),D>>6F=0;F%)4C2*AC$3;H$(97*&#@)0"HF,/E*@9'20:#*H(;
@r1717
TCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCC
+
<F$4'!*6(:;5*:EEB+5'A:$'&-73;->%F2=91&+(F$)G@3%+CD+H%E=$1$..H)<F6"C9"#$<E)0$/2&3)
@r1718
GTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTNCGTGTGAAAACGGGGGCTGAAGCNATCCGGGCACTGGCC
+
,EB".-+EF4+(EBH(#6-"";1.@,CD*"8*%&",CG:A=(!3B;A2H?,*F>9H68554HB"F=)#0*'E/G,>A6/
@r1719
GANATCACGCTGATTTACAGCGACAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCANATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGANCTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGGGGGCGAATGACCAAAGAGACTCAATCAACAACTGTNTCAGNCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACG
+
%#&+$((##'++((%*!$$+*%+"#$$()*!(!+%**&!'!&#"*!)*"%#)&*!'$!$($**$#+"&&+*&$+)!"*")$'&&)+#%%*'%"*!##')#'"##("##+&)*+')"(%'##$)'$$$%$"'"+*&!*+&!!""#"#%%($++(((+&*#)*)"%!&"$*(($($'('&++###(%$%#*'"'''$*(+%'*!%#'"$(&$+")"!'"*%*$$(*)++$%%!)"&'#&&')&)*$&%'$)#"#"#!&!'&+##%+"+"#+"&(%$&$)%''*#+(+!)!))'%#!++$+*$#)#)'+*'$&(+"++)"&($"'&%$%'!(%%"*"'!!%"$!%%"''"((!"'(+))(*$#'*!&+!*+#"((#)%!*+)#'%#)+$''+*!*)"%&#"+''#&#''$$""(+#
@r1720
GTTGGTGGCGGCGCATNCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCNAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAANCTTTACCG
+
<)/<8>:8%0"0F-63-4F!>;*7..*F8=:-&'@8G;?#B/0A"-F!5+<B1.3,5/,<4$<*:%<9A8'?=*2#H(8/":.2D'835$?%.5#@2+5>/B"H*F.1>*0E2C'*H*5!H4F+3'9+<<#)&$C+;:-A(*1A*G$)&<H9-3E(*7-9%8F3G+>#1"'8E8E3724!')+FE
@r1721
TGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCNATAACGGGAGGCGCTGTGGCTGAGTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGNTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACA
+
'++'+)(#+$*&'(%()'%((!#!'%"''#+&$&$%"%+((**!+#*!$%&&&)"+#$!'('!!$'!)&++'#$(*"+#+&+')*$&&$(#(**)'"$$)($#()+%"&&!&%&(##+**"+'+''#)"*'!'+#$)(*#%&(+)%!$+&+#)%!"!!'##)#)+&$&"("'&(*'!%***$$*+'))%+#(#$#!)'$*#$+&&)+"(!)%$*$&+))#*+&$'$!)!+
@r1722
TGCAGGATAANGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTGTGTTTCAGGAATCCAACAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAA
+
G2DH@"+#:1@0?4%?$4F*E5!.".(+5$9GG9+&*A'%E6-/-=1BA;<*6#)%9."B",-*:'43;E;&;9>$*--+A;F1+;@&9)8,0<(<!;*!/GBB@%7&:C)
@r1723
GGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATANCTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGG
+
;<D#7C!;;"BH!83,707.H?;9C)+@,8>->G5-H4>50/3C<7/&E9@B$$4H0GE2G$&)B:)4*)8./,D#>H(2!='C#+$C!;H/A=FCFD8=07!"*816B%-77=G#5BA-"9>&/<8D3+$>.F>)D;))26B=C8#;,3>B!F"D'G%'/1?E$EC.+3)#2%#(0=;78.<EC!763$AD!4=/AH9$('/@-@(01*E66=#6'6579H*=D434FB@F#(.:2;/!==A3B;>";/(5;3$$!0H?7%832=:D8F@F!AE8H$0@?."(6>
@r1724
CATCCGGGGAAGNGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCC
+
D%C?!($"7=CH&C@6-(;(A$,*C0.3>*/99<-!5"E*>@;;):F3?0!%#?:
@r1725
AGGGGCATCCNTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCG
+
?)G4%:'1BD0"C2<2%AB#CD$:-7%D:*+0H'28:>"01#1-%>&9
@r1726
CCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCG
+
481A)G6<599!8&BF.G?,7C48>;5=#*0H<1/?5/>%4($8+6,8H?-"2)A%+?GD&,+E<EG%H@0-=8+-?>&5"E<E$;7&8=@81!(>32H:&6*4B)E?,8)1.?:7>#2:C
@r1727
NANNGTNAAGCNGNANANCNGATGGNGNGCGGTNNTATNCNACATCCNNTNGATNNANTGNACANTNGNT
+
"$""$$$#"$#"$"$""!!"##$"$"$!"#!!!!"#"!!#$$$$"""#"$!#"#""!"""$###"$"##$
@r1728
AAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAG
+
$FG!>3'17")4(F527/&)GD,D2%G01H68)!88.="?$1
@r1729
GGTTGCCGCCGGGCGTTTTTTNTTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCN
+
+31?E18B%6+C37)%$&#)>&9&BC9/B1)495'68/8-;",GC#<5?)(179%-<DB,B.4=/#51129");"(=".>
@r1730
TGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATNTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGTAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCA
+
07;DEA?'B5-C)FF57E>:FCG+)4#40'$+A/8;A/):.6CD9!=6>&+C6EE?7=E&(4#65<(-3%G-)@2E4FD'3,6(;G@:HD.5;)/!&9:8@':.4+8=""D@+.H:=?03E0+A:28:3!F7.>E)*<E3)#)?3//23'>2'*09*$H#HA60?"7%(93=)C#!H))78/>3*.<8)H*>5D16H5'>=CB@
@r1731
TTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTATCCACCACTTCAGCGGAGTCTCTG
+
CE?1+=$-=*C&4!,E/GF&"$D9BH+?/=/+6DA>G?@D6?('G:E-'C/C3936<C6#=2F5@->AD"5'1;B*CCD!2D+(75:E3&HC&*3+#/!6D*><9';86E"%!*5@85B*</-$GD8
@r1732
AGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTC
+
);G&C5';24,2.G!0#E$%.804F%F4,.258,2;27D))2F0@5,DF!7EH<4
@r1733
NNGGGTNATGGATGTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGG
+
)!$&()"((%+*%$'')!(%'&"!&%'&)($#'$"+)#$!$!%%)"(+$$+''*(!$#'#*&$#(""
@r1734
TNTTTAATCTGGTGAAGTTTTTCTTCTGTCATTACGTCATGGTCGATTTCAAGTTCTATTNATGCTTGCCAGTCTT
+
(!()(+"'#+"")#(#')('"+*'+"%%#$#"'%%&%&($%%'!#!%$)%*(")"#("&!')%+&)")++(+&%$*
@r1735
GCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCC
+
H6&@%D"92:(#5,C%@?:;420A?"=?//8&C@2*#80E266?),HG+G0"@1;C,2
@r1736
AAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGNTCCGGTTCTGCTTCC
+
9,<60%D-;%D?!<9E&:)0=8=#AHB+2;=%H6(+)(&D)-,C$,$2"@<D#>(*&20&8#847)F4DF*7-,"9%<369D'F7=;0<>86GD4D?@G!C7!>4+.->22-7%;DE#-(4C0
@r1737
NCAGCGAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTG
+
">+A7)'#D&,?;B0?"!:A"72*285D)H!0$:$H7%%04.=7B?&"EH;A:0/
@r1738
CGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTNTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAG
+
33/5*73486&CC/&3E7)E3!H$:7"$27A?AEF/C.'2,AD1G0/%@#@7D#4G&(#2E9<<F;'0"(,H/FH&F0$"CG1H>!:6%2,79":0!$."E+$H5@+FC*0E90?E?0*(::6(-H(C9>!(,"4(5))'4:D@E&10F59<<(2#9*#E29?0;)D:G&'"CB&<B=<;A2B#6<@>E/AF&4)#;4C1-0H6(<9
@r1739
TGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGNTCAGCCTGTTTGTCAG
+
;DH-%H$/F<!$$,;+/9-*2>!G:-#!/,F$DF747;2#;&6=!6)F)*8<2("6"$=FH<+
@r1740
NCTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCG
+
"H+:-F?89B!'>FH.9"1/&FH=32"!6"2?<):7#2+1/2#!<,E:0+.=-:E%0&1A6:C/<B%73E:
@r1741
NTTACGTGCATCCAGTGCATCACGCATGACGGNGATCGCATCGGTGGTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTG
+
"+(%$)!*$)'!$$*"#$&##+(&$)"*++%$&'%($$&"+&$%#("#*&+!%+%($"*))!#$*%%#'(#&+%$##*#&*%$&("+$(+)*&!))!!)'%#&'+'#$%"()%('%#%")$(')""!)&
@r1742
GGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTNAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCAT
+
)>+168H'$.3EDE*CE$!*%(3%"A6!G#&D5,;&E3E5/*++)'E@=0!<248EC70*+-)"6#!3G:4"C@&,3H<DB2(!G3C&1=$
@r1743
CATACCAGACAGCCNGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGC
+
EDG$;><D,"D&6;0,6"=#+6C>.:>59FD-!B5=F$D=D!B.*8#H'<><G!>8-$'B#<4E4D.024#:2$C*
@r1744
TTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGNAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAA
+
=8$!1;,#-)/$<,2<$<??C5).A".&76&A$1:3<51#"EG?+82!=3=(;8H'0<32C84CAF1E2D?AB)#.5D/E;>#"C.C(#!!514"<H04.:#D)5C+'"90C0H6%-B)C<>92EBF&E2GB9&.*/>GH8<3H47F85/E2C1%=%"%989+HH*7E60#:&A.DF@!=#;!H;EG#)$,=>:E2+/7-')$CF(:<#D(&.$<C(6.!.=+3CD)>.-+=;,2@19:,>61?-@"0<4;G3/1ED516B!BA=@2>*&*<9
@r1745
CTNGTGTTGACATGCCAGCGGGTCGGGGNAACGTGATCCTGACGTTCACGCTTACGTCCACA
+
'"%+*#$'"")*$!"!*#'*)*#*$($'*+!%#!%&%"'""&"$%#)+*#&$*+!+*'%###
@r1746
CTGTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAG
+
EDA:E02+G0$2-&5D-D6&/*#+3G,8F,30%<:$8=.",FAC",G82;!D:E9G1>+?5(62+"8
@r1747
GCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCAGCCAGCGTGGTGCTCTGNGAAATCGACNTGACAGAGGTCGGTGNAGAACGTTATTTTTTCTNTAATGAGCAGAACGAAAAAGGTGAGCCCGNCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGACTGGCAAAGGCACCAGTACGNGCCCCAC
+
63%*8%-)A@545F9:G/3'8D5+E(F)%96)&41<8C1%>8!0(H<57F+H<&?89@,/+"2-!B+/%+.F0&2>@'D)(#4>6=#)?)C9."332=3">,?&",;.45,"C"&=H4'7@"D"H?C!+>=E1FB(;*=23;G/59>.',+!1DF*4!''H@743"4,A)E&0*-C<#5",1?7!CAE?C:5G5!>8!&8:9(&03>;7B'<8*H.5:;%7(,;-&6D@&'
@r1748
NNGCNTTCCCNNNNNCCGGGTTGATATCAACCTGCAATACTGTGAGCNGTATATCCTAGAACTTCANAACTTCCCTGACAAACCGATATGTCATTG
+
"!)#")!"*!&"&)(&+'!#*"(+$&&#&"+&%"#*")#+'$")#&$)%+)$%+#!%#%#()"'&$&)"%&%'(("$$+((*!'&%+!*&$"$*&"
@r1749
GCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACANGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCAC
+
(3-:5F6%#(3H34/,$ED1).'57)4@<,.2+G/<F'/&+4G9A%763<#B+;#1#7@>&<81D#$3:C9,D@=9;7345(3%+'9?G3@66A72",?2&G*"5-BDA<"G-83+3/D,'1)&D'93%=<:4+G:"AA1>/B1#'";G*(B**(!21C':
@r1750
GCAGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCG
+
+!%#)&##)'!%&'%%%($$$(+#)(('#)!+&&#(*%&%*+*%'!&+'"&%("*
@r1751
AGAATGCCAGCAGGACCGCACTTTGTTACGCNACCAAGACTATTAA
+
5G(.G>?:=%H%"/)5!8H-A@6.*>/H#(D9!/H.&281C".@A"
@r1752
CNACCAGANGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGNGCTGGATACCGANGCTGCAGTGTACAGCGGT
+
($"+)#'+"('&)'%%'&%))("#(!)+*)!'!++'+#!'+'"#(%+%%)"+!%(!%"%&&(&"+'&$&)*"+#$#(%!!"#'&(()#
@r1753
GGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGT
+
B>00#0D),'C72?!8&;D>1+F,!@"'2E8#H)6+=3#(3"%C%391C+5(%!(*G#==:AD2#A1,.9B5A:3E"5D9B.5*2<F7+8@62B"5$6"9)F6A,$:/#5DF6=-!>6(;:<G:'!7;4,5A:354A-"2
@r1754
GTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCCGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGC
+
?3G*%CC@&,F:,D#A1.5$>&-*10&;'=D(8&8:$8;##3@F-;!B4C!58=5,G)H>(%70!%<6/-1*,26<,64+1*?7*())&+E=:'C<(41;43.&5,&@7A,1B0H?>G82+#9D2G?*?($"@4>43BA
@r1755
GTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGANTAGAT
+
*16538&F@'5;>>,83=*)&A,377$D6D8&FEC#/4:'309&B"9F"
@r1756
TTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGCTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTG
+
9;4&?7"(34B%%2!8=A05)##HGF1?GE=H0=3"1E3=.10BC1A+8F884"7'#0":G=9=E6"#/6E4*!#$+@&843;7+<"9/E84'29<%CE:;,='89<&>B&7E(<1+6,=*A*)E:4*%19@=$+>FD/74)')B$7A8G-A0+92E@0HD1!<,9/%+15"&$'@B"%7?!/C+??5G-A<!")0GE"7';*F>@E=-,#&=28'!(-*06$9934E.6-1-8!%E5,)0#D./1(FE6<1F954H"9D;09!%0?7*.&F23=G/,&H!/)$F7)G;#%/*"%?2
@r1757
TCACAGACGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACG
+
1,#5'"@.;"#=$'G<*"E;"020%2C7/H:;*AB==B*82-G<867E-=!80E&<,;5A9%8EG(>BAH;3;(,67%?8GE$56'0;*
@r1758
AGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCACGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTANGGTCTATCGGATTTAGTG
+
-$%G'#C=B2>*&'@0H*$)!;?(@34(1,48;D8&0#@%1,1$*&:$+&DH6,D8AADGB*'C,#ADB9!>5?:B9$/$57A<?-&?AA830D)="45)6H#%C"E-"3<<H?-/!FH''8DD:,)%G!0A&$#==DG=B?+40<$1BB&3?,.7&EE$&F?&H@.(H6E"7<A<"8,?).5%B33+4#B)2$?(*D:"!)$/?=000,4(56*=(+:!=#'0
@r1759
TTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTT
+
;G$D,08+.!;-7E!*65$8E4)!B1!8)>>;+<7/+)3-
@r1760
GAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTGCATACAACGTTTCTGCGGCATATCACAAAACGAT
+
H"*0?:*'?'.::!##AG'0A46*%6E<;&,E),/)(%-2'$?=C:!C6A706"D;E>B.6?D-,G.,0'B?&9*&-></!3DH5F"5=1''E4<A51"3HG;9&>$/C,$!:$&=A(5@>)'
@r1761
AATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGA
+
:9&CH76,5$HFEC#6(6@AA/=E1*07&1#?..:C@<:"(=*!@6('2**!(,5:57G.31F"33G8H,-F=D0E:B.&FH:>E.%)8:#!1D#E6,30
@r1762
NAGTTAAACGATGCTGATTGCCGNTCCGGCAAACGCGGTCCGATTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGC
+
(5%()91205*(4*E(1(>)9&G@<="=&!&(GG1=(.$!$;"A8@1.HH"='4#96.GE)D:#5&@>%#A,DDD<5+'
@r1763
ACTTCTTTCCGGAGCGGGGTTTTGCTATCACGGTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCT
+
GF!<BG-23;B;AD%);706)31?G292,>9(:,)0CG*G6E'&3%'./9A1!1.3B$(CGH&4CH;H-30'F@@8)$:$*?+E/FHG35<*6E?=6E'-<CF$9*A:,55=%6:*"":C)C+1=2E9-8F?=!D7B!HF6BE*:%F7")-
@r1764
GCNGCCACNNNCNNTCNNGCNTNTGGNNTANTNACTNANTAGTCANANNNNANNCACNTCNNNANNCNNNTCTTGANTNNN
+
##!"#$$#!!!$!""$!$#!!"!"#!#!$$!"$##$#!"#"#$$!"$!$!#!!#$$"!#$!"!$#"$##$"$!#"#!$$""
@r1765
NCAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCANGAAGCGTATCACTAATGGGCGTGGCTTCTGGTGCCTGGGCG
+
"&HG9=&&.%'C.CEB961?:7C&3'&-?'/#H8?/C<*"&C#++/,2,@$.=&3*@5G9?-CE0GC@6F0$'-6+G@'A83">,#)$*#'?AE26-+E"(A,.?"H@5)6D)6FDH0G6<%!+F7/,<C9?&+&FFH"57-209%!&329/$*:.G+/7!>6@!D*''-#9/3HA:B&3=D"8-#5B.):)#7>B<?)B1@
@r1766
TNCGNCNCACGNCNACAGNNCCNCCNGAANANNNCNAANTNG
+
!"#$"##"""#!#!$$##!##""$##"#!!"#!####!#""#
@r1767
TGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGCCATGACGTTAT
+
G70<1/BD0;.$C27+9=5&>D$0C-CEE6?.1:-4"3=C8/&/:;%,;+"?-+?-&C?6%;*53:$H4A)?@>FA=07G&D@-5H2-910*5<552C>HA"B4:%2!#AE)",F=GBBH&1??
@r1768
TGCTTGCAAAAATTCTCAAAGTTNGGGTTGAAGTCTGAATTTAGCCCTTCANTCGC
+
+"=9(H?858G>A*A.71?$?.,6<"&#/C.AG<?G5CC"24&,*-/"H4=>416?
@r1769
CGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCG
+
;-A1C!7%'GB!09B4:5=F++@3"HF+%)-(%68F0?D7:EH(@A7&FF?F"?GE"<-=H6C==#%&-('D,38%+%B.
@r1770
TTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTCACCTTCATCTCTGTTC
+
++$#%+"*&#(*%'&%%*#$')+*)$&*+)&)''%%$+'*&(+!%'&)(#*%$%'%)*$))$&%(%**('*"&#)
@r1771
GCAAACCGGTAANACACCGTTCGCCAGACCTTACCTTCGATAACCAGAA
+
?;H?F+4E;5ED+*#A4>1,-7*D-GB;A;/6C,=?4399'F=18GD4"
@r1772
GCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTNTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTTGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTT
+
GHD0HF#GA$)4F'';D<C+<26$BA.$):#B/"9=A-9BC4)'/8)4"8"BB?,640<%4F/:&??11!+!4+@@3:-:5!5#2'F7$D<9&2F/G+-?1*$=#>4&&)E3$)&.='%7+('B#1+72E@F156)>$">$B44"4.DH/09FF4=(!A:@.H6,/
@r1773
AACAATGGGCGTGAGNNANGNNGACGGCNCTNTGCTNGGGAGCACCAA
+
)&")('*()"!(*#)!$#)$!"$'*!')!#"'*'$%&&!("'$'*++"
@r1774
AACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGNGGGCGCCCGTCGAGAAT
+
;G"$39F"<?29C/3:13#::'0>G..77"H8:",>D1=2$3/B&E&;+,-"D1;/.8<@AEF:%7=6>83B-*&'..A&(E3/4;$;5@B(BC=8GFAH-:6(<=,34G":++1?C7H@22!)$240BA1G*$
@r1775
TCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGG
+
A<'C*"9($HF(#7?AHD.-.3$3@0@<%#)'<3:5*0<1&5,#+5H9FCH;C)F(A@8$)=0,174#A+*15EB'0-9>A&"CD'.H3*;0;G6!7"=*5F9
@r1776
TCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCNGCGGCAAGACGTGCAAAAAATTCGGCAAAACGTGCAGAAGAT
+
)<98$/*9;./A;/3F,626<#<A*3E1!)*)+?(AH@(G@E1(-G,--*!,(A0"7+897!7#8<B(7,<-H*3'=>3A)F9H;938%G>.#00C*$../A;61)6(2A$8C=";,!63
@r1777
ATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCNGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCNGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGATCAAAGATAAAAAATATGTTATCT
+
2/D%B9?9%3G/!H:F+0;5/B#%E1B<HE<(8/(.2!;F@@0&+9.6G*D&EA4DCHB<<?%G+,@9"=#2C,6$@D'D*@A0A;>A+<F;<GG%+3(,!'7?$!(.GCAG0*'@C/DD@F-;=C"B"+?<$HE-9!7'95-E41/7")3A;#D/C@1/2(2FFAD@)B?$B-B7<)3=:#@7'6"&<#6#?EG/&-&%F410,9>G/H6;(29':.8?G'"?F";<(+7GD82>9ACF&+*%=9"8%A03G=H4GEA:#G-186+
@r1778
ACAGAAACNCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAA
+
F9$>(%-(2#@BFH,G7B-"6,##,)E+;6(25%H#74&61'@0+#6D8-7EE;.HB+F99-7C(6HC$32B.8G/:.,%7,D%/;-,#-'E-.>"
@r1779
GACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCG
+
7/2A-G&3$-5>@*@3@('?6$-,7;"8&>8=E>/+$8,>."/=5*A85(>FDH5%
@r1780
AACAANCNNCCNNTTGCTGTCTGACTCCGCCTGTTNTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTNTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACC
+
)#!('"#'&)*!++)#')#&(&*')#&&$)*''!&#&"*("'!#%*#!$*)+&$$$++(#(*+&))*$'$"+(!*"+**%%+(%*+)%(!')#)+"*("&'+")(#!&"*"%+&*!*+$$+"'+'!#$)*+(+"%+)(#"'+'("*&$$&&$#+##!#"%(!*)*#'(&')+(*!"'#!%*'%*####'&#'%&%+($$")+'+
@r1781
GTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGAAATACA
+
;*H!AH)")8!;F36D&:;!%''B,B1!9>-0+9=B9?=:%$2.30:4G3."?7)1;!D=:'EF1H5(&#H&9E)2=DA923512%.=-@(#>,0.3GB.@#>
@r1782
TCCNGTTCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGC
+
##*"))#+#(+(*!'!+++)'&#(#*("$%+'"!$%(%)+('%+$$&!**"!&*"+'""$+"
@r1783
NNTTNCNNCANNAGNNCGTCATANAGCGGCTTAACAGTGCGTGACCAGGTGNGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGG
+
!!&&%&!"&*!%)*""+&&($")(&'!%!"%%#($*"%$'%'$*)*+&"(+"#$'#))'&*#(!&"+$&+$"')#$"""&$"'$)*(%)$(++($$+#!&(!%(#!+
@r1784
CGCAACTCGTGAAAGNTAGGCGGATCCCCTTCGAAGGAAAGATCTGATGCTTTTCGTGCGCGCATAAAATACCT
+
:';6"C!$D5'?"5+.@-83;,1626GAB2-B;17+6E'A,3#06")@09&0A215EF;D,))0&<G$-#8.66
@r1785
GGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTA
+
;1)#*=(3='3<@H=43(@?E(%65,$.G&=<#C)<B,!737DB9,C=.8/G860B&$*A.!C$F2#.,8.*:A#A023'!B8/<4,>1H;@3#-?;.=)F,--#G=50
@r1786
GCATTTTTGTCGCGCTGGGCTTTGTAGGTCATGGCGTTATCACGGTAATGATTAACAGCCCATGACA
+
?@:#"7<EC@=,H+70$#:,CH=E$#*'C'"F@355;$H'?D>B!!6)/?$1A7,8F.*-/?D:.>'
@r1787
GTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTA
+
:!)+,$@/3,01H<.=3B>/96'3"(*2A57=#FF/65&3%;*82C*$+'9A$?*%76>-92/:3-G41%4(%1@5*"F3='&;EFG.8,B!,5-4">!1+H8,D
@r1788
CACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCG
+
-D>"D%:7$$86/G.96'G2/%2-*:9!0$C&D-8$"B$3AG91+?+;-!/;BEC**E,+)
@r1789
GGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTT
+
F"A/A>B211GF5<GD#6/A:$AD"=*&,=E6*/)4/#-G;A:D(+B+0!8@.3
@r1790
NTTCCTGATGTATCGATATNGGTAATTCTTATCCCTTCGCTACCTTCCATTGGAGGGCATCCTTCCTGACCATTTCNATCATTNCAGTCGAACTCGCACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTNATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGANATCTGTTCATATCNTCACAGATAAAAAATCGNC
+
+F>2'$<>1$,392;"B'03<5E'53,/'@A!B#'B;4/@E4H9"<C1H@D17<<?;%8C5F@9!(4H;2+&E3"A>E0%4,:=*A;.7D@/#9G3?:H:2?G+C.5#A'*:/16/(B=!FD.?C>96/0E*C!5F)&!+,<06F,"D&B;$D.%(,C*4!H:,+E.74;B93:#<8>B+@*<1303F8(2(,*8D0.@A*%,*?>?-'..&2?-@FE3F6!!/%@GB07-=#G753-E/<D1B(H46@;&E!296B5%<H("#/>"0DH1-@9&:1B3#$8))-*F+?H"/;&1!DG"68DC64%4D6.37G9;+F101;5+BB:D,:?@9G55$?<'/%8-C',A?;6'@!1G+1!=4GF*
@r1791
TGGGGTAAGCGCANAACCAGTTAACCGCCCTATTCTCTCGCTGNATCGCAAACCGAA
+
,9$82,/AH.C(":&&F(2%.,4F<'<5$A8.9A9?;*G!6H06/*-@-4&9'88/5
@r1792
GTACGCGCCCCACGCTGACGGTTTCTAACCTGTACNGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGNCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCANGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGGCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTA
+
>-2E2*::!HHA/19B9(0DAG*/%8G#02E1G/E.&<5G,$8A2C4A!0?!*'?$E,/=92',47$;D67;C5-B0>%9$10/BF$&6=@"54>+85,.=873<#0/,$):5C?868B9?(/3G<4:#&4=8$3;0<E%)93#;5ABDH9!>+&*!A5(+;/:C2/D:%F%:!8,G/-3:.C3%F>9,74C.BA3GE@!EGA0;C0%1/$&%0/'*=ED;1&<;(26C6E%6;%(=;-9>E6&5F7(5;4*8<*13+9'>(C0%H7BH-?6E/>D7;?
@r1793
TTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCA
+
)5-H+A9(:?'%/#.B9=.A5:,6',>DB-C)$@,F2!3C5"()/0?B!4*,<5$!1/84
@r1794
CATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGTAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTNCAGGTGCCGTCGNACTATAACCCGCAGACGCGGCA
+
18'4?,AH,,?06"2C8?&!A().2;/=?:F94-'6&(8"5'4#$5=*$-*9:>.1>*5/)3>7)0D1@77A+A0'>ECB2FB7)E<C0($B6E0D;=3GH61@%G81,<)ED!*H7>!H)1#2BG#,C<G09<G??4G.@%B%$:D*B8
@r1795
NTATCNTCAAAAGCAGCAAGTTCATCATAACCCGCCACATCC
+
(")&$!+'#"%'!+"++("!##%)**+$''('#()+*$)!()
@r1796
NGGAGTAGCCGTTATCCGTATCCTGAGCCGTCNGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGG
+
!@554:>*(&&#-B2G>-5CF,C;E3$0:(&/HB/&$A?=EH/B$+G9<::9,?+:G=.1%C@;.:%
@r1797
AGTGAGCATATTGCGCCGCTTCAGGATGNTGCAGATCTGGAAATTGCAACGAAGGAA
+
&+-:D&)<-G#8,>@D3/G4:<;5.,EG5)7(F6D+A&AB-F4'"F'2BB4-.0,(+
@r1798
GAAGATCGCAGANATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATNATAGCTTCTGTGCGC
+
G@C?=04CE;G@EBGF(G4<$0,*2F:C.,4<:=67@!5))AE#&H*-(((>!>6"?/%+2>*G@A"A@2"8$.4:#$E!7E!:.>0+##,3*,EE;,'#3072F9
@r1799
CTTTTCTTTTTTCTTTTGTAATAGTGTTTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATG
+
3'9/5)7'+$G6G0E8%+F@#'2=)3:8")3;:("C9A44E3<-08/*%C&#6B/EB,G(B#A+*,=F?=-=,+H+'<B*,>D"-A409?:5,F2$DG>=+),48(H.DHA!G3+-&',H#>6453)10#"AD=1==+A/D""B?!4%.B(G/3$/6@<GC15
@r1800
CNGNCTTCNCGNNGTNCNTNTGTAAAANGNCNCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGG
+
'$*%#'&(##&"#%##)&*#(*$*%*&#*#&!&"*+$''#(!")&!*#%+($!%!"'&)!'"%($+"$**)'!*(""('$#*!%("#%'%))$($#'$#!"'!*()$#')!$#('*"&!("$$%!(")#(!*&+*#)*&'+*(%)'"'%%
@r1801
GGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGGTACAAAGCGAGGCTGGGTATTNCCCGGCCTTTCTGTTATCCGAAATCCANTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAAT
+
A72/>760)78072$&;(@$-#-+0#*,B>9E%A>48!$@:&-20<3G?)(;&%;2G*:=7@5E@77A')G<C@.%#5)#/630.-0::<:!89/6!A;2,/A%2::.8)C=B&596"=+D3:DBG&'DE;,>7<5(AAG//"AHA%3:(6$?-32<D40>8F7'2;A2%&A-07EG8B%24(E/?+8),?/-H6GD73>G1#*9*##C1#>2D4E+(H#'*;&)HA4548+?<%><479((+;8.1-@:=B:83(+&BH.(#83>0.&8;>"E"&2'A;
@r1802
NAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAA
+
&.4.8?/;3C0AC,276*>E0H&DG:+$,660,><"!=/*)=1D)041>C08/.E2.0.=88"95"H(&,9$-%$29GE<>58-5CFG
@r1803
CGCCTCGGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTTCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAACTTTCTGCCGCCGTTGCCTAGGAAGCTGCACGACCGGCACTTGATGATNCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGA
+
$*'($"+!#&%)$$*""""%"*"&&%%)#%$!"%*+!*!)#%&)!+'$'+)+('"'!$#*+*!)+"')'!*#+$$%#"()!"("&"#!$'%$&###)*#")+#&%'(&#"(')(&*($(+(*"*!$+(#&!!#)!(+&&#(!#$!$(%'&#!(%"$%'$')"&"&*%(%#+'"$*()%*)'*%+&'!!$)"!#$*%&("+*#$!")%%)%&'*('*)!#&*(#&$
@r1804
GCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCNATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATG
+
.D2E5??5HBA+C.#C0:E*333E:H!E9GH<1A+<HG&/@656!DE,@(7(H<G9;C:<")G,@!:?72:.0,?93C<5"E#(F".@DG%?"*!A#ED&CD5-&6*)'7$HB/2;#(-0&+D@C'/#*+**!E!>864:!#-C
@r1805
NAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTAAAAGCTCTAATNGCTCNGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGC
+
"2/:F*1H37<+"09G<6&7H7A<60&2@1G-/G/G%B=E"0$;EAA6"";/9A*F!C?2C.6$,6%,A1;?$1E/-4D.G@7E(<19H*2('F..=<)9*"*E1?0?93$AF=9908:"%AE:C/"39())+3C2#1A1-&@!.&?0H8<#=FB3>04184/3H"".=.%G5F05>(H6BG"4#9DBC.CB!,76!&$8F2BH!
@r1806
AGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACT
+
'.%?G!/8GC3CCH$$@=9==EF8@'>(E;6B&-E--G=4C
@r1807
ATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTNTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCAAGATCTTTAG
+
;#*5"%<=:>3/HB4:>8E2$;;C5;?$7#9C<G??=.E60,3*:%/()59,71>%#C$$.2(4:E%"@D(''AC3#9B%;/8F98$*G'7H=!-68;,(G&"&!&56+H;<56,"!$31&3@F1H(-3E@4+6'#:$%58,#;'->G-.6#H?;@A"''!FA/2)-+',E:;G>"4>*+EBD)7))G2B0$F*/,6<,-GF=F=:&68?-5;C-E(FF$2
@r1808
GCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGNCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGNTAAANGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAATCAGTGTGGACTGGCCGTCAGG
+
58!?)55G"G+!/D2#F/@D*:;@83<2C:H%"4!'4H=F+HB0*-6@A..&H<8-!C5EE;G=1DH!7/5BB1+5=65.F=524'!,0,'A'>2%<*B(':.9:%D)CF7B*:16/<,G'H<5)/9"2*4C>8*)&5,H3*E:@,3H5>#C!4@)$HBA>*9C&E85;95%87;*AE%7FE6&3B>D/9+.(9=0AAG&+C,'6*8-';B<+>C>7--@3A;G*<@F7+.+260H86@<*0+EF!6&7@-@7/*E/'2
@r1809
CTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACNGATGAN
+
5"!;2H$=-"58"H!F%?B2::52'4-!>/+0.G"2C@;:897<56E&H&E"(=BB/AF(6(,<$3
@r1810
CGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTG
+
!5@>H:D6%$E2;HG?2071=-1"?'/D>5,?24C(*8#&9(H@+5A<DGC8F(>C:$-'"H7D5#H(#+$"A,1*4BD6>EG2A%F80//'E-,@@9B3:H
@r1811
GTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGNGGGTTAT
+
@("(=9C#1$>E"-7)';541:#89F<86#)H,.7%!561>/992272=??1@>?66(B92
@r1812
ANAATNGGNGGAAGAATTNCATACGTTAGCNGCATCCCTTTCACANAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGTCATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCC
+
)$#'!$'&#*'+"%(+)*#'!%(&#*'(()"(")+"%$)+*)#'$*"&#!%&''%&(*$"%%%!%*$#%$&'#!+"+%%##"#'+(!&%%&)"#)+")'*'+)##(!(%(*('"%")!**$#'(")##$%#(#!(!!'!$#))%*#$*)$"'#&+"(*++%%*(+!*&!#"!""*'$$#*+'*!##$&"(#$&*$(*%$#
@r1813
GGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTNACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCTGAGTCAGACAGCAACCGGAAGTTT
+
'>3(G*91<);/+6@>.08.2*/06%9B4".&BG:$.AE?-!";2A>>03G#!-<%6>+B&/7-'$*6)>-5=."#74H'C.9(,/;H.,3?/'%0504F)F,D*F-2/A1@103/=>53775/#'14:B)5:3CA0-'+"&C@94D)C:-EH/D6BF*E#:*$.*F8!):"5H0"@)!&4++?
@r1814
ACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACCCGGCACT
+
878?%'.1C2/;?/.0+:G"E/.'9@)&B@1C=;1A<!@E=<H2@-/@?6#+2=:G6C35=51"?87%D;G9>(3$=>.
@r1815
CNCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTNTTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGG
+
##44B4,:F>3A<E-:.0?F,B2AH7?:/%;")!C63F.$$,!E7!,H1//'$:<=68F>@&)?.@D(+G/9D5C,0H80$FC6#>8"2-E9'4.#/<&CG2>,@1505#B0C<!""1H#2('82.'=*2@??+F-4"2B40*.AF%F3!C?+:@.'8+?
@r1816
NCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGC
+
!E;F6):D:%GA83(68+$!.>F9+7,+9/?,E>>,C$%"+'&H&+,4@*EF0$<!*F.,??G3(B:H#B<8"8$/.D'E/C$+=G@3D<0*9/4.,8??BG<B3,832,+$D6E
@r1817
GCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATNAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACNATACACATCAGCGNCACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACNACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCANCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACNGGACGATTTTGTAAATTCACTTAATTACGAG
+
5A19<1=6D#?,?!8@C!+B2D?=E>*?56257;&/9:D(%4"%>;B51.4E6-60E;"F<=;7$GG1855432+:&*!711"@(6BH4-=@:'?.#GB2"0@'?5HD*7=)!.?F%"6,BG/A8,@?1*#.H*&GF>8<B##$2!/C':"%0>BF<'0-/DC#"."A6=$@7AB-0.;7*-H4@0%874.<)%2-6C9$*#G7B)*D@%61C.:)%A-C:/:>@&G+=E@!@/9'@5</<,#D"@0'72&%?1()/4F""04*@6C*5"0B8&1@1.*:8FH315/H%3<F<+/>"?GF4)G(G7>!<>-/2$8!+#@=&*"BFC->5>==.1<@!2#%;0-CGH-A.<%*G@&'B-D@'6+-;6C(H(#+-2#)"+A154*,;A<?G&)'%==5%)C8-(=!3/G+*953;D,&01GD$!!-?&5HB&.!56$89=6/#7.<!CF)8.3<*:G73!C*H=@1!<@=*3D-024
@r1818
GCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATG
+
+&+&))!&+('*"++$'!($"("*&$%'$!#*%$&&*&+$*!%%'#)&%%!%#!)$""'$''"!%$%$'#$"**)#$*##+%%'#$+%!$+#(%+*$%&+')*")
@r1819
ANTNGNAANNNNNNNAGAANNCGTGNNACNNANCCANNGNNCNNNNANNTCTNNTCTACCTCGNNNNNNCNNGNNNACNNCNCNCNTGNNNACTCNNGNNCTANNTCNGNGN
+
$$"!""$""""!##!!$"#!"!$"$!$#""$#!$#!!$#!"###"#$"""""$#"##$!!!$!""#!$!#""#!$"!$""#!##"$#"$"!#!###"!"!"$!$#"!"###"
@r1820
CCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTC
+
,G>%B1E':)()>G4&G@)4+(F*<,<*6"*7008-:#>H@(9B:-GA6=<>B#8*0);4,"#@E&>9*-AE0'*>%A!A=A9%)%*@,,G'@<+#'
@r1821
CTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCA
+
67(G,0G>F#(CF@B+<22.F")D)3'4;@1*2GEG)!-"52,5;#-)2/
@r1822
GTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACT
+
A9#/H/F2E,"(,:(3/5:A(@>+A?E&%(-G(E?D1+#?BG#@+$$E<0+4F4'60!:)++HB/3?CBB>$>D@0>5/6A<5*G<$?%AH1
@r1823
TCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATC
+
)4+)816%3,H44?#3A%$7/*?4@>4)<;D5(3CH'A>H&%B?:H71A%2(FE7C2-C!F(@4)
@r1824
GGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAAC
+
=155@H39+042"(6D0-$>0!,!),*?3D>4?>'@=EC!H#>>52-H=B-F+A?87,,/A5'CGE&;$3
@r1825
GTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCNGGACTGTCCA
+
A$B::-0AF3D&>?E+%B',02*0#E(+7,636:"A,>;;'G9DB+)61-G=(!A<8*'B9-&@C!4-?E$<?<73=+-D,9A-B%E/=0#+C@$<A7:$&8BD+GA;4/B.-!,@=#1%9'@)2+@-@8))2/#&=!C09*B!=*:C"85$%H,/?@5'D/!9%)<>.0#3C.E</44$A))2##981F
@r1826
NGAAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCTACTGTGAGGAGGCTCACGGGCGCGAAGAACAGGCACTGCTGGCAGAAACCCCGGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCNTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTNATGA
+
'3(59")$+'8,C*"FA%,/3%:4""/7#<7.:(@/C@/""'*C9%.",'.A=!/>9,.&H<12@+9(C!9G:)=+5;5&8=F!;-!7@!9@#7%B!?A4**!8;>.F02)A''"/'#)1/CHC::#-E8%D3<3D$=&FC&A4:)#F>C%D139:?8;<86=FG/%D?=<%(-)#1>'F.-+<F4.8!(HB$A#D!%4HA)74('%%E?""DH7/;-=(-6$1HCD)9<>13A58#6@:?8E&,51=7D'7+<'1GA*%$B41G<1?.#12;1&>)G
@r1827
TGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTANGCAGNAACGTGCTGCGGCTGGCTGGTGAACTTCCGAT
+
ED9@@)6#.H!A;>D!E:**%53%;G&&!&$63.9H3@2*<)F?;+F?0&C65.%%%C+0C3H@4%F27-$%*(,C,
@r1828
NGATAAGTGGACCCAACTCTAAATCAACCGTAACAAGCAANAGGCAGGCGTGACAGCCAGCAAACCAA
+
+&)&)*#+')&!'%!"'!++#+(%+"(*(#*%#&%+)%%#'&$&*#&*($)%*$!&!()%#$$*'%$$
@r1829
TCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGA
+
.@C%'=&)E%-,9/$>-/&F=?C#9&3;@3DC-#B%':*1;A*&?19BC19)3&:E-+"51"?600'3%6!+#GH=C$F8B8F/)AAB>
@r1830
TGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGNATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCG
+
3>/0=F)6?281H0B"?D?&4<"-+29:(*FB1F7F>7''&+E-;<%DB-A(D(2F>#=>+$C-'>@1;+"7-!"?$;!!>1GF),G2%@@'H&.4/'/B8,%54),7:).27E7CC@,/0=1F>>D8#D
@r1831
CTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTCCCTTTGTNTCACGGGCAACCTGTGACGCCGACTGCGATATCGCG
+
60)0H1<!*8-&/BHDC#21H*;>5G;?;!45F90F6.?*:<<&00<,!D(463(C=$-<><25*).4+&D64@7<DCD)#.3$$%E7,!7%$69;;%(+1DAH2@
@r1832
AGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTNCTGTCGCGTCATTCATCCTCTCCGGATANGGCACGGGCGTA
+
*&0?@FA;90#G9F:&FA$!#-!C"9>(H86,:)):BB88DC9B+CA-+F:F,$"'@0E@7%&97A<3(>-#63<.(1F
@r1833
GATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGT
+
)7'B!<5:09/->?'+818E,.!@8;G(8.#40?&0CG:#98/175(&**(
@r1834
AGCGATATACCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGG
+
H83$*BC>&$=B(5F10@%;($AE?%3578E@;A?GA>'9)!;/-G4<&)?,!HDGA,0C?8;C0#%,C!F@#-@+C.319G;8'<422D/4D7=C<3A8G5%.8,3$9316#4CFHGF/D>#=93+'5;BA3/<6E%=.2H)3@$/>97-F=G549=82.3G"9%+;/2.-@>%G?BB$+61,/9G9./<0C1?5<0F$"*.D-;E.
@r1835
AAATACATCATTGATTACGACTGGCAAGCATCAATAGAGATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCG
+
</?)=*5.+5=>.,*27)4,'#-!"H*<$F<G.:#;(;/HG3BB><A:<>EC3C$#19;2643)9'3%!GD08(F+#25'.<!=4?)5;.A0F@)4%6,B66)!G/C72G+0<>(C
@r1836
GGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAA
+
+/-2.%9,.0"@/)C16%+F?-GC%-2)32+H.';@E$H&,9%H=3*CG57<C+33(38,/('8.GD3
@r1837
ATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAA
+
016!3G")9;E8;?%/)AC*<<0?6=(*C%5&*$H&F*$.5,%%A66D51+.
@r1838
AGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCATCGTGTTTTATCTCTGCGAGCATAATGCCTNCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCACTCTCTGGTTT
+
:!@;7>(94D0&3!%#395'.>?D2F95BF3)"'>CB@7G5/;B1#9&;:0!-CE@.@5*#E&:-$-'1B2*DH3"(.2!*C&1*8;8D(86C%%7#-287C.CEH*8A1!18C&?C>D!H1=&-0HF$&A9GA3@>2C+!"%-4/1<1A&B@",:+/D4=?,!
@r1839
ANNTGNTGCGGGATATCCGGCAGGAAACACTGAATCAATGCACCCGTGNGGAGCAGTCGGCCAGCGTGGTGCTCTG
+
$$"(*&'"#(%+%)#"+%"))&#$!&$#')%$'#'*'))$!%('#*!"*"*)#(+#%)&%"+$''!+#$!')+%!*
@r1840
NTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACGGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATA
+
&+*.*$8%"@-E>7(*(?BDE4>)!;AG6&.E>H1(:C;4*(038)EH7CB?*E0-(<@+F2?7F44/6@.$.*?@=",=*'FF-)6D.$3!5<H8+8!564<7E7!)'06?E0?HC!6F8"=?.:'*C<:/>,>9;9./D2
@r1841
TCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCNTGAAGGTGACGCTCTTAAAAATTAAGCCCTNAAGAAGGGCAGCATTCAAGGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAG
+
<D2=#.%%*></==4/.E'''$,C@D*283!01)-4F/C4A.41(@%2@(=&+2?%161AA=6A./13?467;20D*4+"%&5B&!A4'<1%>E*0+2)H",:#B'C/-)$<('HC9-=C@$995+AH4#-H;B5HA<F,9D7*A#.9;2-85G
@r1842
CTNACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGNAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCG
+
%'"!+#&%($(!!%!$#)#!#(+%+"!!))*(%$')"!%!+!+&!'''#$++$$'#+$*""$#&#"!&+'&((")%&&#%"$!*&*)"&'+$*'$*)'+$)&
@r1843
CCAGCTTCACGCTGGCGTGGATGNCCGGAGAGCAGGGGCAGCAGGCGCTGCTGG
+
+$;'6B+-??/%H-10&0C'-,;=#B-=$;8D@E;7'51H:!3+%<5;$%H.!6
@r1844
CGTATGAGCACAAAAAAGAAACCATTANCACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATNGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCNGGGATGTTCTCACCTGAGCTTA
+
@A#>)-&+0@C-@2'!8$,B9G"G0'>5"<E==1>/C&'$7A$%<1DE;DB-C,#E%??;:(9?/*&-$8C3+E%E8:-4H23B;(##0<;H,B0C;-014?$&&'/3A!$1,%)E$/.7#?"75121<98$2=@7G60?887+1=70=),28>(=702E"E!&+%>E.3F*5;CGG'*>&!.>5"D5=06C>@>E0+.BE43$56H>><E67,D,C"$)3$"#3>6H49)A&.)56BH(B-,GC(98)9&&4,B733+"86D/?"=DF+%F3=E;<-:9=+H?;-@!6$+*-C*E:5=*)!$,,043$1(;BEB$>@<HDD6"F0A*,$=0>?1<?.E9#6(D#C<+&;$3E6H0;+)E"<A3
@r1845
NGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGNTTGCAGATGTTATCGACGCGTCA
+
&.G:8;7A,::*(*#*1;=GF0"!2@,CDF/+ED3D,G!%A2!(C*=$(+F=%65#5F9=?=%<=G'9CD4+.=%(C4()3%=G1+#>H6FA5,@%!'
@r1846
NGANANGATANTNTGNGTNTTTGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAG
+
"(*(!*!*#''$%'%$&)!("*++""&$!'#"$$'*#&*$$*#)&$$##**(!!(!!!&((#
@r1847
NGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACAC
+
#8=1+>865?#08@B;:7.*22+>4C<FG,4=8*9.90+6'@#*%CD2G"&%=>6F*DDD5B6C>@D7+A#4E2G2!.0!@D5D?6)
@r1848
ATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGNCGCG
+
11'$%'B.=::=<8H8C$FDGA7DB(;H<D&--,(*;&!/9A$=.,$2'.-;0:B43G5-6))4C5G%8E9D!%1;
@r1849
CANNACANCATGTGGGTGACGCGAAAAAATGCCTGGTATTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGA
+
)#*&$'$#+'%+$)#+)%+%%"*)%"!+(")&)#&!")&*#*!&)""!(%$((%%#$#!&$(!#!#++""$#(&(+)!$+%$**$#%$#+%!!''*&''()(&$!"&+!&*&)!)*+$*$%*)!'
@r1850
CGATACTCCCGACAATCCCCACCATTGCCTGNTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGNTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTTCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAG
+
*<4:#);HGEH4"/F**$.H@(G'&.'"622;;7GE"0H>?B=C!5D(C(2EFBG81,>(C/.(H#A*&@-B86"/4.;24$C>3,3!B;#6C4G*A#>/<?(?!?'*=?%"*A1A8A!H73!90)$3A!DEA#")@C)E,01&1'&B@FF:#)43FHF,E!0(HE".>-E07%<"6#&6?/B017FF?=-(/&*'2C.F,H,4)$:?G-><,$C/HHF6A903H.'-@05.=HG5!%AG1
@r1851
CTCTCAATGGTGGCNGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCG
+
:+>4*;<+!B<,'H:1.;/2>/BAC48B-5?A+;>'D&H5+$33%>71'@@<=(E<%)?*")><EH;@5!6>!D!E1?,!)2C6'"#?*B40#B&$@5*>)?%$%%&6.3'9,.);
@r1852
GGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTNCAGAAGCCTGANGAGCTAATCGTTCGGCTATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGC
+
(0:;*,)*C6<,%)'D7%(E>,(1?<57<!<A,%#-HH-B5#8A<;F:<)32&">+"?5A,/H;B#E"@%)14+5D/#-HG905B;83E'88ED*D%A0(>GH&8=148@0D.!5.2!2!$"F/*42B<H*!G3"2.EH0<,EGC=C:80G-;?/:<D
@r1853
GAACCCAGAAGTATATTAATGAGCNGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCNTGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTANTAAAACCGAGCAATCCATTTACGAATGTTTGCTCGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAG
+
:A#+%F$6E"621?B;(@9);5D)9-7,9&)8"1:G*G!:>";9,39"=F"!/4!&%3%<@#+?4GE!=.!9B;2$3*?8,?9=!2"A*:?%A/DA(9*!$E+#.!=0C#;2@??1/;"GD51%52G/87(<)+<E(B?$-;F00C24>6B#$%GA&"1$A@8F,<>!&F%@><DEB*=9@%0@"),/96!A%GE;"<"0-:,#)B);@
@r1854
ACGATTCATAAGTTCCGCTGTGNGCCGCATCTCACCNGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGANGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACG
+
F(#%>*9>%7H.F.)6(+16%.)03E%($..?#0$)/2$4=,&,H:@3(:%56/G**5A5!78:='.B:3G/<E7#05.?1=H&26H"*8.A&?!8<@1D6".+!>><!#C%HHF#(;/D@9.)F?//C601&)H6FG?"%G<1(6/0.0&
@r1855
CAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTAGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCA
+
:$%:417!!&=B1&$><5.B!7+A%EC7.&.A=0D,E9H3(*DG@&A(!G>#H#<2!:C(BB+=*%$=(8#">)<%6'E1#1@2/!;G-'?8>H&DD29.@%:$1=6"/A$-).(.<
@r1856
ATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGN
+
'+A;8+&%49?*(D?:#HBH839$9&4+5GE*<@2>,GB-=@2E32?6E,E-0.9,05HGGH54/9@E34?@-?A1$C&>6F"(?E%&:;"@7A+/28>1HAG)');4@E"
@r1857
NGGATGCGNCGNCAGCGCACNCCNAANNNAGTNNAGTGCCTCATTNCGTCGCTTTTTGCTGTCCCACAATAT
+
!$$!%**)#%'$(%'"*("$!%%&*%!#($(%"'%+()'("+"()+!+*("%%*''#!%$)#+'("!!&&#$
@r1858
GTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGNAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACANATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGNTCACGA
+
/=/#$"5#<C&B7))*2C-0"(;$(<<",+*!6&?,&(*,'*>*45?$F%1"B53<C(>8B*F57:0B7.26%D4:0<7?"B0)0-'$5:&(&4HG-C>5GD!!12F=".H6:&&A6*,A>3<%9B"GB7(&@>'=&1?=:576C(/&%5A!B8#*.!%@AG-'1(0$-1''&/*#CADG).4&;="C,%5;"$2C*$%;"(-@2H8.-%272?%#"/52&:2DD08?;7
@r1859
NTGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCNGCGTCCTCTGTCTGTTCAGGGGCATTATTNACCACAAACTCATA
+
-1*E(!#F6#,'F;;7.*;1<4>2,6<(<7%4.F<6-26F"27;=>D1A%E364.(BC"6FC6GG@=)>&.<"6=CH8?$FH**41/2@.<@C=5F)9@#(?27C<.F*#;*7:G5@&2<2FC92.:)21!2))&@%*+)%"'7**C1!82+?:":FH5G"2:2#3C<9>#"7>=$0H?8!<B<+5A9(.)$"#+3G5D<3>;BH,7&2!-7
@r1860
CATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTACATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCNACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTACGTTCCACTCCTGAAGTGTAAAGTACATCGCAA
+
0AB#%3'@13%D3?>01/"8)"*#?3((3H+1@8+<=GA($/@9+8?-./2A#3*4,+,<="%99C%C$3/72+*?G69GH>0&++BC,'$#BF,1G4:8:;?8%#&!G""&&G8DHD=8&146C2"#=7#">5A<7$-?AGG..%*%(@:9"8A:&',0>@<<4>"<0A-F74&7*#GC2A17B=:'2G:G:18D3*.B=-@'
@r1861
TTTTNNAGAANCAGCNCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCNTTCATCATATTCTAGATCNCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACNTAACTCTTTTCC
+
))()##'%*(!*)$)+'#&&)&$+&$$'&**(+#&%%**'"*&'%''#$(!%&&(*(*!#*"*))'&&+&"(+&"'(%+'+#+)'$$&&+#!'&&#!*"$)#(+)!)+*%""'$+&%*&&+")+(($#+*()&%#+$%"#%
@r1862
CGTACCGCCTGCCGTTAACCGTCGNCGCTGAAAGGGGGATGTATGGCCATAAAAGGNCTTGAGCAGGCCGTTGAAACCCTCAG
+
=0A+5.2D3'C;0>)A>2FH*@H'*%51!6(-@=6=36<+=<'E'="3G10F#D8(<.-)"6&<(1B&&C0)08'%#;$H8$&
@r1863
GTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCTGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGNCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCNCATCCTCAAGCGCGACA
+
9E@GA;2#$#=6"$D7#?#+HD9@@($'6588',1B(E%!@).+)$=(?E9&G"!#F6"E)1AC+'F!!617.E@;E:GH$7(?=59ED,=;+9H8$$(!)::!>*$F><@F:(/@>0?#H"+9%H(%#*?7A/,GF"GA)@2&))7@.:G#&G8+6'D2++"7G/?/1'&88":!A@63!BDG@"=,?2/)F83*"''?;'FB=3'#(6+23F%5;>:"'18B""#F-,@E,::?:="C3;;BC"6"GB0FA(##-*0./#
@r1864
TACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGANGTGATTAC
+
$:*4',='E0*'1H@$G)8-&G(CGC6<&#7;?=80G<&B?2A2G2D549#:4,+$3!?<&1F=5;*5<G!)$/0$;B0:E2A$#!
@r1865
NTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAG
+
!90'%"@%?<H1(;'D#-%D!7=+4:=*A83:1$1='-G5(DAE)#?GFH8G%H)2D:!(!#='A:05:;/AH653-59EC$&(B;#(/6E$)+C!>FA"B:)>G(%-7#:H33"25
@r1866
GGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGACACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGNAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGANGTGCGGCAGCTGCGGCGTGGAGACAC
+
214#<25H3)DC*(<(2@C$1?(43'HHB@B503)E779;0/;-,.=++H3(>F#A+'$FG*?9*3!&8.'761H>=4#?)!%@6C$)D)(!<)H:0,2DD'-;+;+-%!59(497G>FF86?0G"$96G'>0<$,D@:5FE-:!$1,:;@#ED7(:,0&85979F,%H#D)#3F<F?
@r1867
TTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGG
+
@62.-B%,0F2*GA>6F;*@39>82"+-#''5101!&)$-G9
@r1868
NTNGTNCAGCCGTGNNNNTNCNNNGGGGTNTNNTNCNCANNGTNNTAAAGNCNNTTGCTTNNNCCCCCNNCTNCNNNNGNANT
+
"#"###!$####!#$#$"#""!!"#!$""!"$!"""$!#""#$$$"#!#""$"#!#$$##$""$$#"$"!$#!$$$#$$"$"$
@r1869
GACATCTGNCAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAA
+
&(!#'$&+"!'"#+(&%&'"###*%*'(##+"))%")&%#!)&)))!+($'(()##'"!('
@r1870
GACGGTGCTGNCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCT
+
G1.#(7CF:-!;9=1$#(-G"H10D2EAB@'+5>7%;33%2F:*30D..8?F#9;0::2$!.E;
@r1871
GACGACCNCGGCATAACATGCAGCGGACGCCAGAAAATTAAGGGAAAATNGATTCCTCTAATCTAGTTACTTAGATATTGGCCTTGGCTT
+
'#)!!$#$+!'%&"&($(('')(!!)*"!%%$$()))&###)%"("%)%%*)('("((*"%(+#!+*)+*$#$*(&(!!(+#&%)!*%("
@r1872
NACATGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCG
+
!(')#+''!($"($&!%&)+&('((!$#$'!+#%&$$""*#+)$'(++(("*+(&$)'"#%$''(&"!"++'+!)*%(++!&$+*##&!($$$%+!)+$''+"&&"+%(&&)
@r1873
CAGCAGACTGGAGGAGNTTTCGAAAGAGTGGATGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCNATCGTATCGCATTTATTGACCCGGCAAACGGGA
+
>7<#255(4)7%;@#FB(&$?6D,=2)B+D>D%9(=)5+75#FED8,?1*%E!5?A'4AE,@"*,0'?0C40/0?H2(%#G2,BA!63F$(>/9C,<:H.D7/,1/>,0",<GDF(66G"BA)9C>57D66G!*:8<<7)=5;?&24+E=B;G*F"@<</+.7%3?D=A&D"-?G>'1A$,;/6!G.8&825(97;E$)F@0!G@6
@r1874
AGACCTTTCTGTGGTGAAACGGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGATAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACC
+
-$G+B$01F>CA-'G:!1+'(98F<#+F-#>9!9%2,HFB>$*G&22D>BCBE<H=:?#1:9:#?72%1&/40F#1-:E=GA4%-,*0AABG+$'G0+B;3$8H8)+(!#>C&%#-G5;+D-<A@C<&<
@r1875
CACTACAGACTCTGGCNTCGCTGTGAAGACGACGCGAAATTC
+
D)5"!?,!%$#HB/@7'5A+ECB3C+5;$9B%3*2*)DBC37
@r1876
GGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAG
+
7&,A'F;59.'0!!4EB'"><=+C2%3FAF48%F+@7!#$6C7:2-3A<*7H
@r1877
GTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTNCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAG
+
'$9A6<6+!ED!.+-?..=&/C;!7*7?.;A/33"<@HE('8)*B!.F'6;>!>%%E,*6*'7-#6<""5.F7F(!.++B:30%$D;F#@30>A!5:E'"2#D&8,$$0,G/B,3$9$@(('A6'+!<E5+*A+:H@$(55H%F@>$1F==$#1%9;A1#=4.:;>6&B8F:GA#-H1E4'/D51A34*?,+G.9"D,439*!7)""8"5E3+!0GE$:%=-$(."<2B)6
@r1878
AAAAACATTACGTTATGACGAAGAAGAACGGAAACGCGTTAAACCGGAA
+
('$#*''#$'&#+)#"+('(!(*#&+*(('&"+)%)!*$(*&#"*%)""
@r1879
GCNGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTC
+
**+*+(*##''$!"%*!$+($#(#"&%+(+%%$)%*!&%%+$''*"(+#'($"'!'+#(&#!&$')'&(+')#("%%!(+!))#(
@r1880
ATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATNTCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGNT
+
B*,H.'!FGFC;9/#D$H,%"<,79'<2>#@"!"$.$+H6(B=@43=!2&3.=>87E/C8%,.8,%C:6@4<'/<))860(F8@8(5+,H<?%=)$2A%/CDF=4?2HD,5%=($E6?'#$+<==C,D+;C,9>E8(,B2B2-6>D2>B>7,BH-2<#
@r1881
TGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGCGGATAACGGGGCGCACTTTGA
+
-/B1-=:=?:1F78%*:%D*4/5C<9B:%8*@E5E*E/'E>#-*317*E#9B-:;8!&/@%B+0E?<B*.!,?$E8?A!&:%*25#H
@r1882
NATANNATNGGGNTNANGNNTGTTNNNGNGNTGCGNNGTNGNNTCTANNNTNANTNNNGTTNANNGNANNCTGTNNNCNNTNNNTNCNNAACACCNNGNNTGNNGNNN
+
"!#!#""#!!$$"""$#$!##"#$$##$"#"$$$#!!"!!""!$$"!$$"###!!!#!#"#"#!!!!#""!$$$""""!!#!$"$$"$##"#"$#!!!""#"$!$!!#
@r1883
TAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCAGTGAAGACGACGCGAAATTCAGCATTTTCAC
+
<63)5E6(F6;.H<3A5!%&AC707G':A!#+F<HB02C#$'9%A.(6&*61,3BB#HA,0H.B$#F"@8=7*%C,B>%"0H<6?)#(C-;4H1$:>;</*H88!3?=
@r1884
GCGNAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGNATGGTCAGCCCGAANCGCATCAGCAACCCGAACANTACCGGCGACAGCCGGAACTGCCGTGCN
+
"((!)*#+'!&&##')+%%#)+()%#+**$'*%%#*$*+&%'&!&"&$&(*%%'"&"('+')'#*$%"+&!)#"#!"(($(+$")'(*)"+#**&%!*()!"&%(+&**$!(&&"#$%*'!"(%#)$&&*#*%!*#"%('!+&*&&+*%+)+"*#)!"!#+(*#'!'%$$"%&)+&"*%%+&"%#*)
@r1885
ATCACCGAAAATTNAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAA
+
B904'"'-D+<7E=)7>3F5@&+&7E%:,95$/1*B&;A+F4"+.;B5/007;.#'F+D(=,68(.=F"--?44?'G7"E<(.:=,)'=F8)F#@9D-8D
@r1886
NGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGAC
+
$=#%;F;0B8%662-6#;)$$-(@8<###AA7.312:4@6%/6G&&-CHA6
@r1887
TCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGCATGNCCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACC
+
=37:H?B"?<C"GD-F06'=7,#).>7;*5F+&GD.870$/>A9+9#$-35?D3'-$1GA15G0&C4'2'=3?*=&H/0!114:27G<'4%#8(*5F6&>!*?/)F&@?@&&!F4!>.%F3)D+66"(<%E9:D&4$@9<,4=797,64:-G8-B&CFC0F1%-+0%!.@0F2>+>:G64#).5#=7*AA)(>3/4&&FB)%G9
@r1888
GTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGNTGATGCACTGGCA
+
EF5B*?77E0,.!"/(8(>4G0=0DEF(%)CBD-)>:AC<19@+.(,@2:".55-/A;"F27<F2$A66&+@
@r1889
CTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTC
+
>812*4)##9&GG.98'BEE'=7'(-#<G3:$49'CD0,;>/8-D9DG>(D<!<-:$!B+)C4<8@E88A&A$45$*&D2+$8:+7977?H=@H:7.4"&/G&3<9@)1+HB*D'$,/#=B145<G,,6&:#4@%)(-=E!&.'-&:H
@r1890
GGCTGCATCGACAGTTTTNTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCNGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCNTTTTGAAGTNCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCT
+
<H*/+$.B16/".>7H"0+0/@+<06.(B&!@6>)*>!H$19149(-*E?+D$B!,3>)CFF5#2D95/;F+2F=&%8)+%.->1004B0E*;2)H(/74F?BGA"5$!,F%6/=?/9"F('=C)!9-&7=AE'5.0H.?4&H+"6)EGF;'/4.13$1-F7");;!<-!5-'?+57DD*,2@8B#?.=E<!C%?86=)60=EDG?#*B8!7/+06'*E2'+H$('548
@r1891
CTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATTAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTNTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCAT
+
')'$+*+'!$&)&#!'&"!("")$%")&!()$'"#&&!$'$!+$$"))"!+('&)(('%!&*'+&(&'$')**"!&&#**%)#$$""$'$$%""+')+$)(*"++#(&"&#"(#))(*$!"'%$&((%''(+$*!"#*'#*)!
@r1892
GGTATNCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGNTTCCGGCGGGCTGTCATAACACTGTGTTACNTGGCTAATCAGAATTTATAACCGACCCCAAC
+
*(*!"$$+)$!"(*"#&'&'&$#%)#*)($")"&')(##%("#*$%$!(*$$!'$!*'#+'&&%((&#&'"*%'!*($)"!!(&'$#+%%#&#"')+"&)+%"+*#&!$"'!$)&*(*!
@r1893
ATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGNTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATAAAATATGCTGCTTGA
+
>&D)3:H'A(;;7(5.7!'$34E>*=4!%)"?G'*&+6(D?7<0#3$0%B4((:'4,8/.F+8GCA+"%<$?.0$1#3$+H"E-@;8==2438>%>,+H13>C0)7+2D@/&B:="9)1@6E5*/-%FEG*.A
@r1894
GGTGTTGTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGNTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATA
+
//%;B,#*&DHE)%A3A5!%B66+&$15C*1#%/<'>10C:42:,?@6;D0(!$<@'F#(4A4C+3FH..B=C6<+G2$8+CA"G0F;@3>GA%7,@1'5)+3;C/FB$FD<-84F?3E&>2@$'B<E/3(G1?/&:%;'!8$-:8'5
@r1895
CNCATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAANTCCCCATTCTGC
+
%'")%+)!(%'''%(&&'!(&$('#'$*&&()&#"('"*%#$#*'*$&(%(+'*%*$(+"&!$'"%'$'!)#+(#%&(*+$$##(#!!$%'&)&$%$*('(&*&)#(*((#'%*&$!(!('*")%%(&%)
@r1896
CCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCNTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGNACAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGC
+
+3$&:@25<'/;=+>8B-74/+<A&B"(#*C51(;E#?#@/=H;1G"./",16>-".E#449$(:7#A34%F9"(<,.:@,0,&.G92/%#+=C/B/!2-6+%?346.=6G,A/@D>2%51124G=+E?0DD7/2#5*5D'?%'.#;D$6HF1)9%>H+?69H&<D4/!,-D63B&#
@r1897
TNNNNNNATAAGNNCGGNNNNGCTNNGGANNNNNGTAAGCNGNAGANGCANCA
+
#!!##"$$$#!#$##$$#!!!!$!!$!#"#!"$!!$#$##!!!"!$!""!$"$
@r1898
TCCTTGGGTCCCTGTAGCAGTAATATCCATTGTCTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCC
+
A5"&>4E6>9>+EB(.(83F<(&9%*#663GB5,?&-#&=D@E.(F717)#&,!"$C=/*#;9H'+(F34A>!GG1"/"G8A+$**:9
@r1899
TCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATT
+
3$8"*7$E40D2-CC:$C'(;,G%26'<+'3.-#3&?1),8H>C1A@
@r1900
TCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCANAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGC
+
2=&7?D9@D,(D/;HC;F!(D'=/$?>$H3:F0G,2:"B3%&25=<)?88C='7-7H*F)'3.<A*@!(9$1(A@,3&6!++.898A(;A*?E$+!(EBB5@F<;<%E,D9<6)-EBE7,>8A3>06>:"DB@)@4<(;(9.2(-,7(
@r1901
ATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGNATCTCGTTGAA
+
3@=00H6E*#??F>6FB'@"F6+>32%H:2$1'A.G=2D4+);=;&6!E5>A88#52&>4<=-,65B?:<-E1''!<)F)=G=-A&G$(<.8,>)29:/EC3(%
@r1902
TGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAACTGNTCAGGAAGGATGGCCTCCAAT
+
F2&/=8,$@A23122="?2D@GGF,0;=&*D-B==-!<7-#&C-755D%8)G:8:/C8B,-02$"6
@r1903
GCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGAC
+
*?1=46;@(/CH@18,,&AC,(BE$'7)/)3GB!&3B*(1E@1C95<:"*0$.B7D?90G2DB'.BH785=$602%:%021#,C%=*FH24=99G2=#8$3/A
@r1904
GCATANNNNNGACCNANAAATCTNACTACTAAACACAGTNGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGC
+
)'*$)'%!%!$#'##'!%&&%$&#)%++%%&('%&$""%%)(!%#%(')('*%&'+!*+&%*"++%*!('%'**+&*!""#"*$$*$!)*$)*&*'&(+%+*+!'#'+(##*!#"!$+%)$!"#
@r1905
NCGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATG
+
"H(@3',"+B@H(<<(54%."4"8C33>!)#2<DG0)<3".H$1?5DB0+1<&-&,29B#H1.ECAH&'6:-0+0'0G&A%#&B1@.
@r1906
GTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTT
+
9H)2%%5"=*8C274F&($25&=2E7/?G%G%@7=4A$@>AG:4$221!&!F-:
@r1907
AAAAGCTGAACGANAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACANACTA
+
:B-%,B'6.)6HB<)6-5-1A',#'*'H3'F2;BC>G!E!>5F7</D5D9A020(:&*;/EA=2-,)0<)!!<<*6GH@AF
@r1908
TGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGAAAAGGAACAA
+
:3:29&.1,$B!+1$;87;$?D>0+;#<+;6%&BG6.31-=#7<'8CH.AD:%(96
@r1909
GTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTG
+
<411=E:0:<1#*H$!H2C?,##G?ECD(E;?H)1G/)F"'-9,FHH*/FFB75-;?.7%$B$#0#1$C7?"#(1#FA>>4@*#&4&-E),8;:!2%.>32@B/%
@r1910
NNGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAG
+
$%+*'#+#&(!+(*+&&&'!)+('*'&&$$*!&'%*'$#&&(($(''!
@r1911
GCCGGCTGATTTCTTCGCGTCTGCAGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCACCACCTCCGGCCGGTCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAAT
+
6B?3D3-<383;A>F?5C'CD#?B&F%G3=0G*.!(5B6/H/>,&4D12-90@6$*)2":E"*@CE=%5B@;;+E59ED%<:/=):;=)6:33<B!A0F$439'!?37!)0)DD!06)0BAH:$E><,&(('&G@(,!8.)E&(&1BH1;G8$#0)%.
@r1912
NNGTGNCCTTCAGGTTGTCCTTCNCTTCGCGCGGGGNATCCTTACTGCTTCCTTTTCCCATTCCTCACGCTCCATAAATGACAAAACCGCNCGNAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGNANAGAACAGGCAGAACATTGCCCTGNGCAA
+
"%*)$*#%%'+&*#*%&'(#)$%%++#%$&)"&"()+""$(%&)'#%%*+#')'#!)'+))**&&')+##!"+%"+$'"($#+%&#)*)")*)&(%#"++'(')))#(&%)&&$#+"%!+!'##(()"##!('))""$$)'(%*&+"%%*+$#(#&&*$"$+%!&!#'%&)'#%'%*+)*!&'')+*$+"#!#*!#)"&")+%!*$!"+**%'(#&+!(*)(#%++#(!*##$)*!'*$&!*('(+
@r1913
TTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCTTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCCGACACGGAAGAAACCGGANNTTATGCTTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGNATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGNAACCC
+
2H*2G1+(A=!E0'392=0;=/B>/A+$"GC#$)=DF$;4+46+;#('F+:%HG):,":%>-"E%1,02B.90,,*"!H'63&213?'D)B3#=G<=/.'E5%B;E=1=/1$8$?!#$1?)+D%.H%)9B3H8"B.&'#'383E.9""**')AG$4(@&<<#?)CH-HC>!C!?.?=!,44/B*#,?$.C8%'+(012'A140@.-.F.;3C"+!6A9+?6)=1*F:<:-8A91=$3)B=?79G1E!G7@&9*;F<0*'?!4'70+'1#0(;D;G62@-$@GC+5)2'C%G<::=G</H/<B"?D/
@r1914
GAATGATTGAGGCGAAATCACATNGTCACCCATTGGATTGTTTATTTGTAAGGAGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGC
+
())'&)%!"%('+$#$$&)&)+&&#+)$*"+%+'+*)&+%"&%!'&*+)%'*%*+#*("$!(!"&(*&")$#%%#*%'(!*)$%$!%&"*(('&$')&$*(!)!#$
@r1915
ACCGAGCACCATACTGGCACCGAGAGAAAACAGGANGCCGGTCATACCACCGGCCNCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGNCAGCCCCCAGGACANTC
+
A/9%&!,,C6(F5E@<6(0*F3>0819G%,7786"'7"4-#$*)&81$9A/=D0+42346@061$#G$!(61C8HG-@72E)8@5D8)500,-*?,'(3B+'G!=G**3C<69*5F*3>43&%/0$",+3/#-D91
@r1916
GGTAATGGATTTTTTGCTGGCCGCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCNGGGGCAGGCCTTT
+
HGA;@B0>=6#3!?+F!#%1$:8E+724-*+7)D5.H?C<>2)E?.>@&F659?D4H(57!2C.3"D/,(:1HE"5D<0(9
@r1917
AGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAANGTAC
+
&(%(+$%*%"(#"*!$)"&("+!&'')#!'!+!(##(+$!"$$"""+)"(%+&)($'&!!
@r1918
AGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGT
+
@/4:(;<89/(9>5ECBH!AE)3;/E):>5+'14%0)<?)6@,3&,*E
@r1919
GCNANNGNGCGTAATCAAGCTGGGTAATGCGNGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGT
+
(#!$!!'!&'"+#)+)(&&#*(#*(!()+($$)!#((&)&!*!)%%$$"$*+')(++"")")'$)"')"*&(&+&'$"&(+"#"&&$+((*)*#"$'$(((!#'!!'("#+*#$&+$&!+($&$)##$*'+&(''#*##(%%'&&(+%&""*'!$#"$++)!"($"+)%*$(("+%%%&!&
@r1920
CGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAANCGGCGTCAAAAAGAACTTCCTGCCG
+
+)&!)+&)!()*#!'!($###&'%'))#&$+)&*'*+'%&'%)%#($)%$$*$'#***!$#!#"'%&
@r1921
TTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGT
+
274&'<(HB!+;G19;$&61;2G8";C',06+))>1>)("2.$9315&%)7HE+H8/$>!EH967>(4..,7%G
@r1922
TGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGG
+
HG3@1F2%#<F<GB(+A-<(.,H3(+BB=&H$-/@&<E<88B>>'0(?2$6:,+6'&/8-B+!!:!E5:?GA(A$'!>A&;?.4=%!F=)%&/:8*6+*H>(,0!/G(65)-*-!5($B#'<F6E&HDFFC.%)H
@r1923
TCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTG
+
.H$;1,39F'C'!3$E#DE:4&""?-*;9>)=>B)4'EF;<&%F,#+E%5BAA/+"#-?5(C:%><&,<@/*25;>E7F@#,6#+$>H2A;'<+08A+GHGG=@25=,64BC*&("+'*?6'=H'%
@r1924
NATGACGGACNNNACTCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCNTTAACGTGCGCTAACTGCGGTCAGAAGCTGCAT
+
"&'&"$"%''&%(&!+($('%$%&%)'+*")"!()%'#&&&$"$&"'!&**)$"()(()#$"$&'!!%(%"+&(%(**!%$'
@r1925
ATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTNGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCG
+
9;$?35G5+@1-G<15-B9'B/@B891:D+">$%#A$#0!!#/@+-(3,+G#H6'/-+E/6H;#))G&;)58#D?E(1!@,812,E!*3C9$"H:*@+;2+GB7"=G&+-44"..1!C$A@BC31<&!/#@E.G.198D)*C)'$?.F1;-7)/!A/C-5D2D091&%A&8+C&,/>0-?-$E
@r1926
TTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGA
+
!8+7D!@.@+2(!&-'9+H"..?C99792)0CC7C/FC4'5?-!5,G+E=6&=0(&5<&8:*
@r1927
CATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATNTACGATATCAGACCACTTCATTTCGCATAAATNACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTC
+
&0(&HF%%,$$5$F-,#,2!*D'<22$!%(,5*H?=6="%:B+"8AD17A+0??B;F97)*3A)D.#/A/DHG"">"0@ECE(.+E#*G%C7A:C6@?;AG!4F1/>4DB:F@&>%"9<'<-:?5)4!$#"H9)+3"&GA@F(AE!1(<#.>6HA/!?/!<%40:8BE(#<9G/;.9AA848)&,G:
@r1928
CTTTATACTGCCCGACGGAAATCCNCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTTTTTTTTTCG
+
:3/7C?#@6<>=%-1492=#2),4(4<F!,2'<<07@:-),=/:9H'-F%3E'?B;=&)="<E?'&BB(=21C<+19A+<,'$%9'*F';
@r1929
TNGNAAATGCGNGGGTTGTCCTTTCACGCCGCAGGCGTCGTAAAAAGGGGCNGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTNGGTNACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATNTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTNGTGAA
+
$"&!!*)$*$%$&'+"*()%*+!&&%'(#+*$(%*"$#&#*'&+*$+&'"'%)#%&)&((&!%+&#&!'&)*#*!)"!''!'*&+*&)##'&(*)##&($#)'%#+!!!*&!!())&&'#&$++)&($+)($#*""''*)*%+"+&#!!!'$'"#)))+'%&$+(''#(+"*+)(*&)'##++""#'""'%#')'))$+
@r1930
TTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTTAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGNGAN
+
?%<)!"5)G;G5C;@6"5E=F2:1HC=+230,0"@CC$?42,+D3B-(%:F6;3(F!%0C<(!2&GC=*CA5F!/2$3C%",<6ABE(/6)1@.*;1><<F(38?(%FA
@r1931
AGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATNTTACGATGACATGCTTGTTTCATCAGGTGAGAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCA
+
:<AF"!G:59,#C=-13*85D+@3;);.0D5/+6A&:&2E6-=4<-D4G'=,#"0'!6&7/+9&2:F:F6*!D%C233FE*"D6+C'/4/?'C2)G$,*57:H"=>(08"=H:5:D'7GBF9C1A=4*!0>A4E7G/.>>@+C'&3)<+7:20C4CBG66C5A*-,(&1,F%)5)
@r1932
ACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGNTCCCATACCGTATAACCATTTGGCT
+
22>?34!";'6!.$#)*0>2G*2-"@1?'1@.3H5.!H/),@06)39$&@<="G#;@4G6(%602(+,4H*B"'&!)2&
@r1933
AGCNAAATCATCAGGGAGCTACACGCTCCTTTTTTATTATTCGCATTCANCCTCAAGCG
+
,EG"BD1?%?FCH'5&F1#@6CH,0*(<B>823:,/?0./"C*2B+4/.!??AH":,05
@r1934
GACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTG
+
H78E6H<9B9G=2?-C+/!7A0B8!5=8"!9)(0";;2&2<#H$%6*4:D/F>H,:%<5-GE5!'E
@r1935
AATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACCTTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCNGCAGGATTGCCGCCGCTGGTAATGGTGGGGG
+
</!D0"/"<)>#GH5#B$>-.,96?H78>39+2>90)8"#5=/B"F'HBG5@#,*E("!>!"6*FGH-7HC&9>B45;.B<5EGC0>&F-(?:-0?$;F81D*&>?>*9A+0D87-;:)0E3!-0'#./AE):&/B:D8"FG?D@E&D(6>@;+#A#--:5-E=22(<-F+E9;G2CBF(0E4#E&8#
@r1936
ATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAAT
+
/G?@5:'21/6.,E)'=DA&&=70B=?8C>>1B?D86@0';@/B68#0$(+G
@r1937
ATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGNGTACAGCCCGTTCACCACCTGGGTGCAGATTGTAAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACG
+
9C,"%)F2C+C3??6*,1>-G9,:#4B9*+080%=?E90B):)@%F7'@#76$1</=85D1C5/+7G96&G<"..1,<F<=;"<G6*(<H.1C%,;C>5AE)F6(3F>74E@.DE,(%?D;!$A<?17=/#>9#';,666"&G6EA6%>,BF;=48,&9*=&(CDH"'0-
@r1938
CACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTC
+
B8?7"61:5&H6+;A?D00--DF9</6'#%/B!@H&?=09<:G17?5)@1("9&$?83@=8)..C0&3)=-GB22"91"<#<D0+;6*;)-.$F3>!C(@8419.0952':7C3>4:@@',&1;)
@r1939
GTCATNCACTTGCTCCTTTCAGTCCGAACTTAGCTTGGATTTCNGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTA
+
,H>,-H#6BB5+&#H??4H1:.:#,:)<5;FE*8)1;@?C:=8&D4,"?*-B0C))8G;BEA-?1?<($="+#A5G7&6D-+H
@r1940
TGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGAAA
+
'"'+!)'$+'%#)((#&')+!'!+$#&(#*()%!#!!+)+!'(((''#
@r1941
TNGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAA
+
+5@97>D"2=;/8?)&E"D41:C.<A22.;1!?,H4%4>8
@r1942
TGGAACGTATANGGCGGAATATCTGCCGAAGGCCGTGTGGACGTA
+
!%#)-?$@5=0<::GE&?*18925F:.)C:?1=>$86==25*F%8
@r1943
TCGNTGNCNGTATNGNCNTAGTGGTTGNGGCNCAGATGCTGGCACC
+
&(#&%$!#(*%')#'"$$("$!!&!('!)%&"&+!'#$('(&''*%
@r1944
GATGAACCAAAACAGCACAAGGTGCGCCGATNCCGTGGCCATCAGATATCGTTCCGTCTCGCTA
+
C+*5F9&C:2>'6*5"%?*-C&%;.-8C=3491*<!7F=DF:69*CCBD/@9=<2;(,1C9;2:
@r1945
NGAACGNCANANGGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGNGATCGCACCGGCAGGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGNTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGT
+
$%"(&)"&$*)!+"!!$#*'""'#)"+$+!'#+('"*##%+#)*&#($+"++#((+'%#!%#!)&%&)&+)$*+%+*#'&"&+!")$)%)#)!)!$#&%+'!!%*'!*#!*"#"&!(*((%'#$'$'+*+$$$)(%%$%#%'*)"$(#+!()'$%+!!()"$*)*+$*!&"&(&#$)$""!&&++"##'(($$)'*++'+%!+&*#*("*#("+*$$%%')!)*("""'#'(!&$*
@r1946
CGGCTCACCTGCTGGCTGCCGAACTGCTNCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTT
+
;/":CCHA:@:!@$+4+GH2DD@=9E$G)!8/BF!4$/*4>)#=G9C<7'?03H@"A+$759!>-"/--%0*>*D)-54%H953"G,;%*A0,>1B@9/3-!?#%0-",=4'C;D&;6%
@r1947
TCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAA
+
,H9/=(:B)D2?D53;=8'CC@:"G@(8G,<%2(F8*!D*.@:+&D
@r1948
CGCCTGCGGATTTTTGACCGTGGCCNTTTTCAGCATGGCCCTTTCCTTTACCAGTTACCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTACGATATCNCGGATGAA
+
%+%!%$!#!)*$""(*$'($($'"(+(**)'$!!%*'!"!#!%$!)$$'(**''%%"%#(+%#%")$&'$%*!#(&%%+#&(&*("$%%&"))&&&)#%!!&&#&&#"*!#('("
@r1949
ATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCA
+
6(,?6E80("<B338!+B@!9<=73G!+4H4'5!'&C$(4B
@r1950
AAGTGTTTTGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAA
+
/.'$,5+33+2=B#FA89G<0F+!F2);D0A75BD*H@#569-7/A2$+
@r1951
CATGCCGTCCGGCCCAAGAAGGGTGGGAATGGTGGGCGTTTTCAT
+
**+H:*#!68(C("-!7B:&%5"9=;1*'75*(A/A;>""#5-<<
@r1952
CATCTCGTGCTGAAGTGGCGNCCTCTGACGCTTTCGTGGCCGCGGTGNAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGANT
+
)+&)%*'%*##%+*!)*"()*'*$%$*(%&(++**)%(+#&&"%+%%"#%+$##+#("$#"*+%%!%#$%"&*$(&*&#+))*%#!()!!)'+$'%&$(*!%!#'+)*$(*!)+!#'("("&$&+$'$!)'*"&(#'%#($&""
@r1953
ATCCAGCCAGTGACCATGCCATTCAACCTGACGAGTGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAG
+
,<+)-F<3&@6F%<28*3'D5B'@#=$&&.+;*F6AC=.(-2B8-F:G(@2-G0@BD*(:<&>/%HHF>,0A8?"+.$=
@r1954
TTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGC
+
B8")B;((B,$;5/,1'#"0()E?=F;#<?8*H=#,G)?FH(/)E4?6;")
@r1955
TTGCTGANTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACNCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAAT
+
8!""A#BA81D>%6>DA2>3.53*G/+*&!%E$F(,.>7GD1,>>$4$'.A=E*&/45/4--H/A*+&@'@5#"AH7D6-45F6%0-..(/GFFH!.%,AGCCC()218649>1235#CFB3=%!#D#%$1)?61(1;C%4$/-B*5&1HG9G$C2H7B='*)0:,BA8,)1";53483H#/B6AG;
@r1956
TAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTC
+
*)BB#6-?**#>(,83/1'0G>52'+869&60'365@85+:17"=48F&.&)B%G+;B+?(3F.3'$3B@D*9)8155&(&!(@#?9<D)--.#@#F&##6>'H8E=..8&!34B4A>81,A2C+$H:#+&.@&%),@@6BH*3@(@6(E%0""=?*GB:.6?%'"183B/.3+F06<"@"0*1/E>1(8H>973<4
@r1957
AGCGACACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCA
+
.3-;,2,="<04/1%5F8B5G4.9G;DCE;DEBEH"BB&F2EE%D2C//BFA4:GE85:3&+3&:'G'(?*<@A+75(<#7=.4<3-7"?EE<2B47:47
@r1958
TTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTA
+
/0(5$H<7?D0$C'#!"(7"H"B(+<98>338C-D/)===:B;;BA$*%1,E.E,*E85'%!D<H2A
@r1959
CAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACCCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCAT
+
):1H-.38$F"#(55-&;.*2.5EH',-H??)5HDB+6:!:>G,5?H=#4E"25@?)6B;.,B#5)$C-H9*.4A6E!2(HB!<+C-0E-!&84<
@r1960
CCAGTACGGCTGCACNGAGTTCAGTATGTTTCATCGCTTTA
+
-?8G?)'D8:$E2BC<E1$3<1@!$#7"2'BE4<:4BD<&H
@r1961
TTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTC
+
1'6/2>084=9%8>$(88).0;,&--@<@>@2.=<8$"3AC%9!C;6&5:8@H$#719)'"6
@r1962
AAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGNACCNCTTCCCGGTGCCGTTCACTTCCCGAATAAACCG
+
@99!<%(>+/178C1/G>7;B4&C8("=H8DC<+*/D=+.@(.1/&5>EE'G5789>F&%<#A->F6,9:*'9C"/1E(4,5<1-?3?5#6D,5<:24"65&*5*
@r1963
GAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAG
+
21@<H%G).G,F9819;87.%C36G.+!>AHEH&:*0E=8.@
@r1964
TGCCGCNTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTC
+
G6%G%"C80//,@%C<)=,$F-?9$C2:02E132:H*C"@?$G:B<F?)-CF.380G>1'>>D5/&BEG"$:&E,7,94@(&?'D$,6<>H)<--A-C7!?=/&:1:1F:?/'=35C9%>G.1$?F*5+C1H"&C6(*C=&2C=HC39&CH-)H>/)3E/%-+8&9GC=,%+*@9)$4;9)BE
@r1965
CCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTATTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCG
+
E.E$)H"'3/8#F$B)9"<1@!H.5>:&H)05+F1$;><>(&>G#H,6.*F,;9110<2"*2D:-?*7(($4-/CB$G%:A1FA=ADAGE(:#+C)96%9/510C&"+A@(%F9&)3B2<67G=/.7<GF(<H'7
@r1966
ACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCNGGCCTGCCATNCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGAC
+
:<+H0=F@D#=(!+1-#05&1(696?-&4B1>)"-A5<%4$="C35#6)7<40H<9G)&$5;<=<*5,,?%;D*,,3(-D9%E2&)528$6$04;0%?"D?8=/*5
@r1967
NGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCA
+
,!4*':;?#G@A=5;H7D589%,1@&>:1BA,<6$##4?=.'-!+0H,%E#7-7?+0>"8"*>4=#8$!1+)A./(4'9B"F9DA<&>2*EF/;1-H=>?!!.6!%"792B7'<+68:(
@r1968
GGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCAT
+
2:F='F;<*>!)F@E@8+G61E@3B"=,HD049F6'>4>-%6.2(;
@r1969
AAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATAT
+
9)#<B@:(59)7/;2!0E&A=2@G@,'3*5D4<G<4*82'E2.8D<*H
@r1970
TTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTA
+
=E'9-:/8;?@0#+GG*1*C9).,"3=887G("&<H"D2+%"1*C<,/D;*-,B0;0G
@r1971
TTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGG
+
4=?;8,$)2$C(&@94595;.9,,;5)):5@8@5E2-4!B701'D,@,19G=!H9:;;
@r1972
CGCATCCTGCTGGTTGACNGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACAT
+
&6/6-%A8+D@DG/>>E@,BD<?B7D$.3.1#-@#/E4*;#*7))!@#;806E#.G.2';#!5*
@r1973
TATCCTCAATNGGGAATAATATATGCTTTNCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTNATTAAGGGCTGCGCNCAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTA
+
GE?CG=?>E7G&!B<+@%$50)-EA9G!7$64.H;,4*+@<+$=3D">A&>54<+1.&>2)0=!8G)2C<880H9=<<2<6F,!F-A4"<C6H;%>$-4(5):BA@$AGE#(07246&-E';57==(9)>85%">!7>3D/@72E*?).B&(+(5&?$-D+>&AB147G2?++2<DD4E+
@r1974
GCTGGATTTCNGNCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTG
+
"'G3A4D(,'8=GBG)%)<#E3/9#3?7*A=4%>#35:)CD92<=%)$@';'D><>$F2G<60#/35!&?0,%7C<,?+@96/
@r1975
GACGAGNNCGCTGNAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAAC
+
!*')$"&(%'(#'")+$*'&!%#&&%#'#"%((+"))!!**&%)'%+!#*))#+!"(#+$)&'#%
@r1976
ATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGT
+
E18G*0H#@>E9*E7:+=5:6/!*:>,(G/7G)%G2#//B<.6!:43.3>79).8H:?6>#A-!5D'G
@r1977
CGGNTTTTGTTTTATGGAGATGATNAATGCACTTCCGAGTCAGNATGGAGAGCCATTCAACAGAGTTA
+
)'&$+*%&$"*%*)'($*'*)#!))'($!&($$%"+"+$+*+*('(#))!&$"+%!%#$!)+'"(#%&
@r1978
NNTAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTNAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCT
+
!!"+'%$*$+&&&+*$'!$!'%#+($#&$(#%)!*)&#)$*%$&'&")(!)+$"((#%&")*&#*)!&*()!"*%()'+''''"+'#!('$%*!$!))#++&"&)'!%#+&%*$(')!&&)**"*)%%(&!
@r1979
GCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAANTGAGAAGACAGCGGAAGCTGTGGGC
+
'<!9%<+-%@GAA$*;+H;06!)08C794:&&B,@$&.)&FABB(@?BE*9A)HH/#BDG&<,#)C7#:=9EG7DB4B4>2$@5<C"A<'@=0FF?E3GE!!E1@B;C<2"*4B4;&5$:/<%#0@%'8@=(E;BG4H$;$<D
@r1980
ACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCNGNCTGCGCACGCGTAAGTCGATGGCGTTCGTACTC
+
,0E6:0B2)>;6@A$D/<*11!'2*G0&C3)6&4C&0</.E%6CC>H#F&G;(,.%)00);>1:*4D9#!EDHEBA9
@r1981
CATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACNGANTTCGGGAGCACTTTTTNTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTANCACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACCCTTTCAT
+
:(87HB)39BG1&=1(G&F&@'HA@BH/G),+$4;;6-(94AB7A"0.H#E.40)7?C>034(&%!+#794?BGD"E"43F(4&*%:0;A$'@7!-A$51AE*D):";(C8%;7?9$-2#-!-*#$2$#"'-CHF@,A%A#C2>E?*E$4,'$A(9*@#7(7.H"B8(4..%..-)CG90G9D;,.%2E,-,*/>GA4#4)
@r1982
ATCCCGNGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATNTGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACNATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTT
+
&$')((")'*&+$'&&%$*!#(*#((#"#!$!$'!'&#$++('"%!*$!+&&&!#)')+!)%+"$(!"'!$'$(#&)#)&"'(*($#(&'+)%%"##%'!#+%*)&"%)&$'')%+$)%*('&'!))'&#"%(#""%%$"#$(%""'!&'))%%+$%*#)'+'!**&+'$"$+**'&(#**+#+#((#&')&+#*)"($'+&')#+'#"
@r1983
GATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTNTATGGTTTCTGATA
+
>58.C>25'"D#EH+60..6HDA><=A%-6C">%(E'C3,=':(;-*<:A$'A!H.D
@r1984
CNGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGGAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACNTGCAGGATTTTGGAACCTCNTGCAGTACTACTGGGGAATGAGTTGCAATTATTGC
+
0?A6(,'94?B;.F>.('0!,@B@"'.;C*=7@1C3H)5*8D:(5++!<+B':H:H2F'%6.!@&99:E@:"/@><;=@EF-")&E+D17')0D+?!C&C'8#8H!,29).2--!0@%105%$''/7E>H%+>!C8*7/$G7$384D!:7F+E1+-&!:"9/0B+=)E(4?"+++D/-0CG+FE75)H*:-A">%!;&ED3).HA3<)4.3CD)6G+)%9B%H7&024%(<:6.C>+!?51=/.,3(?!#+6
@r1985
NNTNGCAGTTNNCCCAGGCANTGCGNGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTACCGTCANCACGCNGCGAACGATGGCCTCTTCCAGCCAGCACAGAAAC
+
%$#$*$!)")!$&%*)*''(")"*++&+!)'%%""#)"!##%"))$")$+)))'##'&*#**!'#""""+%#*#*+*!"$()&)"#"(!+#)#$++%!!"()')#+!!%"#"
@r1986
TGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTANATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTC
+
31.7!31;'$H5$79H"/D<+9H/6/&>%E3685+>"@<!C,)5DFF)%5107-=$GH8;>7)AFG=,<64**7.-44%>7F29709C0C%*%):?.9D"E;($CC?!C:.?>68.7&&9*<>*.H9>41A'(4B:B:*$5-A/=#6<'+A*BA5?*="';
@r1987
TTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAA
+
BE"6!#<A/:!9#@/234@'6#CE=4D&>0'E?4F>%$39+;;8D$9"-"*?9'%F#3/>H2;394,0)&,%6>H&A-696*=8FGEA&=5)$<$#'FF:$,;%6&0G$C
@r1988
CCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCA
+
B'/1&D->/@6.+94+,C+3G@78?<FA#*)BA6!*!((')'.//-@A
@r1989
TGATGNCCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACG
+
+(+8:521:B?(';G*;GE<11-A(&5E3,*5%F@/6%B?D3!A>
@r1990
TATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGNTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCG
+
(3:4GD/41>-B/%:=78"2G"88=%D6,<1:)+#B9A(@"FG?$?2,B*@@4.@C(':*2E?7<-0'9@3-(A,/<47;<14A7+26/'&!B%B>BG&C7'@GFC2AC#'&2#8#8-.2@C6*=$8-8C(%?5C"@/&8F,*$$/7F#"4
@r1991
TCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATAC
+
DH'4<9624.+H)A+7*2-.%&F0721:6CB*<@!(.*G7;H6:-&@C)*,HE-GH-=7-=0#3F%
@r1992
CCNANCTGTGATNCTCTTNAAAAGGCCACCTGTTNCTGGTCGATTTAAGTCAACCT
+
($!#!!)#$&*&!*($)+!*'!$!("+%(*$'(%"#!$*#$%("'%*)'"&%("!!
@r1993
GAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGC
+
.6)%#@&4;'@!@C4!"%D'*(4=!8-)A9%;(5>D)CB#-';$D5>'G.-0$"8)"?5(CB-AD,E6>5?-)97+;*((#"2BHD"CD5BCE
@r1994
NTGGCTAATCAGAANTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCTCCACCAGAGTGCTGCCGGAGCCTTCATAA
+
%+#**'$()+&)%%%&#'!$"%('&"+!)!$)()+$%(!"#(&#$!&!*)&&%'!&""%()#!!'&$#"'!!&%%&)%#")%#))+
@r1995
CGCGCCGGTTCTGGTGATGGCNTCTTCCACAGTAAANTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATNAGGGCGAGA
+
.=2$$@8>78&5.9*<&=88;#90(GA@F,#E%A!:6'"A/,5(03H:-A3HACB%F<$$%B/(-$=(+$<B+5B,)A2=%B%$>=B(?-.
@r1996
CCCAGCAGATACGGGATATCGACATTTCTGNACCATTCCGGCGGGTATAGGTTTTATTG
+
DH6-D,530FA$<#G'76+AEBH:@7+,GG6.$"<AF(69#A@<486/-5#G7F2/%<&
@r1997
GTCTCTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGCGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGNTCCGTCTGACCGTAACA
+
&))!+(&!!!'!$(+)(!'*"%""*!#'%'(()**&*'!!%*(!($%'')%#(''+'(**&''+!##+&*!")%%"'$*"+!%!*!&!')')+*$$
@r1998
GCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCT
+
F886,?+'E7"$E+D800*&AE<85B!%8;4*12@B0H>?E2&H93B);F66-6H0%
@r1999
AAGCGAGATTGCTACTTANTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACANCGCTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGANGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATNAGGTCGATTNCTGATAGAACAAATCCAGGCTACTGTGGTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGA
+
EA??HA%-'*"B!<:.#:?>4F04G7&"H@0=%9/E<=3');!"76AD'79#-+799H+%@>D.49-E76;#FDC='DC).<2#<10>DA$A>>,%D$&32DG<>'(-?F7+>)H?/$42"5;4C5,92"%+0,<?)3)10&EEH@$@%D*4#$,A@!:(3'+@(+)!&E1.D15(@<C"-<#B=BF206C#40*)FF/3C<<5%?"-0@(F4-*.>DAEBCB#E9B'E"+<,6?:5;E2<(<EE,B74/%*3%0<A#.B?0D-2>F+AB$$D6H)$H&,>>7A!4;!7E.G=H#78:(35CF6"EC$1BF!F259@H3:016E/.AH>A:=+'0;$4-)5E=,;;7)!:7:"."C,16-#9(
@r2000
AATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAG
+
>86>9:F)1<'&$GD?&!#!/..42*;ECHA,:"'.F-:/D)6?CF>0/;>,CG31)9;CG@/>(*@DB.!A)D"7(():3B1,!7%/!:"<;'>1D=3&F:&41*/C$7?@/5.11A=/@'7:"
@r2001
ATGCGCCGCCTGAACCACCAGGCTATATCTGCCANTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGG
+
%A?7!?9=;<:6"B?G7&>G2>C4=(E4+55!E$2GEH4=E%5$,G7CD+*+!125<6:%"7$8.B,050*;(=$#5G$F"4
@r2002
ANNCCCAGCCCGGCAGCGATATNCCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGNACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGNATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGC
+
$#%$(+"$$%#+!)#*&++%"""*'%++"$##$$)&($!+!')*#$)#))$&'&%#$)+!%$"*"(!$"%!%+)'%$*$!+'$&+$(&)+%$'(++&!))*+'+(()))')$$#*#$'$#"'$%&(&+%"#%"+&"&('&"$'*%"(+$$$&'#'+&""($!'#*"!!$+&$*!(!(!*$#)#(')&"*$()$"'(')%$+$$+"$#(*%+%(+%)'!&)'")$*(%)&##"$#"$%##$%%!)!*+&$($)&(&%'%!&*%$#&#
@r2003
AGGAGGCNACCAGGCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTAC
+
?(18F;>3?141<);%1.91F4:H<B&(5,0-D/)2F>H8@-+>A?B>HD#9C?8-'C?1$4<(");24''61,B6BCE
@r2004
ANNACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAA
+
*$(+#&""$!*)!%%$(&%*&%*!"*"&$)(#*!&'%'+&')")))#%
@r2005
ATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCTGAAATAAACCCAAGCCAATCCCAAANGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTNGGATATCCGGTGGCTAAGACGTCGTGCNAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGAT
+
(1@9('<=34(,%/B1*544+%%8""7C/<4?@+F1G<E,)'>6!A#F:)2D@'G,-!0"8<(09<*(=A''*1&18*+ED*E>%!)'.0#A$@9/7"((:B;;H"3E5H/D7%9D@23@/2#"*7-<22FD&%.>C%122"@E>#1-<<8"#$E?H)86F1)80$7<!D36A4<-@E90#+7@AD.EB59.(AFC9>?3(:H/-+&"4?$1.FD:;15F'$!D@;,:<902=H='EAH?$=,<0$/'",FDH'!'E93*1*=E24+48*:
@r2006
ATGNCCAGCACGAACATTCANGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGCTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTA
+
)FB7/#D''4>,<$7-9$*3HD&3+&+/!BH6B5:)057@)4''&-"$0H14)!2;*)C$=C64+!768#B1C6*.@"+/:.;#>6,E42:D/*';9:.A6-"!D;0,"FF!BDF6.*=6=@4:A(!(=1BE0
@r2007
NTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTC
+
+/C$*7/1"90)&FE)F)9C8=F?<)$'$EHG"+>#"B?6HE<GE,G58HH#8+$'+2#8
@r2008
TACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCG
+
B;@E"('")67;=9<,9@#EG-;)=;/*72<</E<89;D.=4*4:1/*"H7
@r2009
TGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACNAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGG
+
0=!,-$:9-711/405G'1#D(D#24AH7%+87A>4&(B'3$AG-6)E!),"F?%EG%:A5@53$&GHDDF8,7+&"(
@r2010
ACCANTAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGA
+
181%3A3"5:2*441&H!45F6&<:0AB.,C*%.A5-2;$-7;4;!+:=)".9
@r2011
ACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATG
+
06?56%.?>4*4:0$89D#,,#-F%+F+?1394G!A,+C0'%+"&BEB!+6"$@&C975?BH8'AB8@G1'7+$@!BF"1*#;!//$?E)8(/A6)367>4)!.8+9>6.5'=1-=2<5?5
@r2012
NGNGACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAACGGCAAAACCACCTNGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTNAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTA
+
%)!%+'((!)'#""')"!*!!)&+&&&*&+#%!+)$("+"&$%&**)()$'%%%*"+#%++&#**)**#+%(""!)#"%)"'(+'*"'+"*+")+'))%'&&*'&)#$(%"'+$%%)+)##*"')!!%#&#)!#)%(&&)+%'*+)!(!)&"!%&#!'&%&+*#*(*!#''()%&!''(&'%*&)!(#)(&$&+$&"$%&$+))#$%'(&%%!)*)(!%!&!#+'!)*!!)$&)&!))%$+)!)%'"$)&'&%)#(*$+&!)*&&("&'!&*#%%$#%)##!#'*&#%)*!$"%&#"(
@r2013
GCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCTGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCA
+
E435D%1F&4;?"<&'2'+))&86E77>H:.297*(!EA=@-900;9#>D.4D50<478!56"@:G@GE2"/;=&*E#=?*/,;0608B=6?%&?GE>0=!'9$8F5#B'7H1@>)'3E65/CC43H*47@#1F@2&#9?*06*A9>0*>;(@<5F6*H1%;"%A08
@r2014
TTTCATTAATCNCTGAACTGTTGGTTAATACGCTTGAGGNTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTNGCTTTTCTTGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCC
+
+H%F!)?60(7;!1'?.BG80'38D*-,#7:#G#AG4E6<:8)<6#:H8&1E&?2$*8##<C((42E//>.H'*!4C*C5%H=?';?+?=7H;+H7F,5A687GDB%=846D0(!7&H-2=))0$!&2"2
@r2015
CCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATGCGTACCGGATGCACTGGCACTGTGGGTGTACGCC
+
?B7BE5:1#:(9-/,B109:D.8F82,=(C?415#,AA8>F)%F/"G,?)"?46%?EAA$!7E<$848E63.
@r2016
GGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTA
+
==FE$!3'2%*/!-!*<$GB.3G3$-5-#DE(<FGG$>)E,!<.12-B8>":E*.D+!6+D<87C690/2!:@!:,0"=(,3/,B;@::?H3:?0!B):8F?%#38?=.10B;?9CC$'1+EA)<D=-(/A
@r2017
TTCACTTCGTTCTGGTCACGNTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGA
+
A;/:B"(67%<%829%6#G9?*E10.7/(&/+,?E40E-<'0./:,>B4DD?+'.@&2:3@
@r2018
NACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTAGTGGTAGTGAGATGAA
+
$+%'("%%&(&*!#'&)$$"+&**%)!'*#(!)$$++'"$+'+$%%+!$"+!%&!"%&%+'#+!($)&'++)&!%'+%#)*)%)%"($)+%$')(!)&*#*
@r2019
CATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTA
+
FGG"#$28799D)H4CB,DH.04%742)=7FE1!5-C%8!E"6BB)4.1EG?:&$,<0>G!%97/$5<1'HE%&
@r2020
NNGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGNTTCATTACGTCTTAAATCTTCATATTTAGAAATGGGCTGATNAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTG
+
"&B34D&?C!:6G%)./43"E#?)+16!04A/849<$%>C>*1+4<<!(D,)9&7/'&5*F%88#;?A?:96G/-FA$D&471),5=,4+-3;'.G&G5<:$F!&'(2$"15-:!'EH%%;B%EC54D8@A(+-?50F-4"@++D"G-D<?G5FB08B2*)(8D
@r2021
AAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGC
+
%>8A+)A7$<,?F",.3<F5$(;C3;38GHAD%)2;2:'3
@r2022
TTTACAGNNTCACGCTGCATGACNTGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCAGCACAAGGACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGC
+
%*&!)"$$"!%*+$%$!$*)&')#'+&!)&&%)'#(*&(*%)!+$$!&"('*&)#%%"*#$#"&(#*(*")(!('!('))'$(+!#")&&))%!'%%*&&#&%#)"%*"+!'$%*&+!*!*"!#(")+("+'%+)'%&
@r2023
CCGCATCTCGTGCTGAATTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTNGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGANGACGCTTCTTGAGCTGACGATGCAGCCTGTCCG
+
9%A')E;%'&D+"")DE$46<,!>,",%=<49<1*'>*?H?=1A(86?',8D!'0@?722DB)H2F9<43F!-26,>C((+A:<A/:2*,>$9:/;D732E43&*='%4C>80*?-=":D4>0/=6''<,?"$6F(2*,<1B1")D.9:5*&&6,<1=F4A$)#-9;92C&-AEC/!H1H>%1H9,9GD9+&<&B9+3E<!B/.6-E+71,$)>F#9%8&(G9"A6DG@&F9A56F/6(#!F
@r2024
TTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATACTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTNGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATC
+
B4B&F%F&@5:2*6E&9'H1&CD%/,4,2+=4/C%)(7@.A?&56%@C&-64A'F*"201'E?1H6;0-D;G#&2G+>:<3!9B?#H2>C=06.@)3->%96195A($+6:/G/21)/?H2G.,+=G-C'"-'@=H8$)%/F<'A5><>>H<2%%:B;.F80DB3(H'=+?8D%5.@?"<*#<7F$-;?5.#>'>'=C109D)'(A8G0.
@r2025
GTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGA
+
B$;=H;G!<40<<!+:7,4>BG'=#9->09EFG%=*H;9=3:%"49<;4F'6
@r2026
ATGGAATTACCTTCAACCTCAAGCCAGAATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACNCATCTCTCCGCATCACNTTTGGTAAAGGTTCTAAGCTCAGG
+
G$G)+5;?51#1>**H%%'>794)0864=-*"4E,GE+0!*%CD'67G58%22.9A%@D%=?12(G@H?F@561D8H+B6D3B"+$:;:9C/;$6/A>CA7?@"
@r2027
CCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTT
+
5&.D$/78H'0G68**8.757A#D$!E2<$D$4DB;#C04H;C=@H
@r2028
ATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTNTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCA
+
=:A',15%;&#2%8!>"A2C.FE")+""6C&>6C58=-D)+-H:5=6=7)29>(60*'4F=,5:;H4B(1:;1*CE0/4G:8++52,A/H86"25,/D?"*/'..!;C1@G>GB93C4:9/1*<H%(G!6
@r2029
TGATGTATTGTCTCAGGAACAGGATGGAATTAAGTCGTACA
+
2'!G+>$%*7",-?E7=4.>3E0)+D8D=;>?"@572)2?%
@r2030
GTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTNGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCANACGGACAGACCATCACCGTTAACGCTGCGGGTAACGCGGAANACACCGTCAAA
+
+H(72C:5$A*=7*:0A.8,/)969F-*-!FD6:.27-B>;G!:!)2&8:$G#>9H6&?4*9=!5,,A77":A7>89>0.59%7*66+##?H8G,31;?<A.1!56=G*1$(+/6.5&H:,"239A"BD+;<%9'CC'#.19()C37"!A7'H1#:,'C7&@7
@r2031
TTTATNANAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCNTTACCGCCNA
+
*#*$)%(!+%&#"%)'#*'#(#)'")+$%&&*#'+**%"%(%*$)#"'&)*''#*&&*"+('
@r2032
TTTTNCGCATNACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGTCCGCATCCAGANTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTAC
+
D+EA32E-5@88;.<'2>C%.DC9B(CF6G%4;&97HB"/HE.A+G6$3);C+/3+=B)!25D."65>8("#2D''$>'$5.$27$>#F<2=);-+*>=30,"/99<2F&3.5C>D:/%;A0=>?!@($6<5>B+**4)+F$',$*G@"<%C,D6AEB/)>G
@r2033
AGGGCTTTACCTCTTCCGCATAAANGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATNGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAG
+
3'E?DF$&)3.?$4D#"?C39#-690+9;)F$6GF@65C:D47+2?FG2>@%!DF*<)@(H!5A.;#@57;FF7#60:!;"$.+18-"&5(;/C,G($)G,!)9(;:!4"4H(69'G(EF804'%*'$)<:"-($:9=!>%!4=/7<3(*3!D*#+059$C7,,CF(=85@C0./85@&,&=71&0/B<7>#,)%?>36'>%30E$F0&63?%BHG?'
@r2034
NTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGANAGAGGACGCAGGGCCCGCAGAGCNTGTGTCTGCGGGATAGTGTTCGACGGTGAGCTGAGTTTTGCNCTGAAACTGG
+
+F==)+$C3B9;1G?38F36;/;@':7(<?D'+<G),!):B4):#2";D!A<9-9)#3!H:&DGB/<73F2C/-*<0@D&6E!%+"5?0,?F+GD/B:)F!!5)'62-(.9*2/1$
@r2035
GCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATCTTCTGAATACATTGTCGCGATACCGTCCAGCGACATTCTNCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGNATCCCGTGATGACCTCATTGAGAGCACNCTGCAATCCCTCCTCATCTTTGCNGGCAAGTCCGATTTTNTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCCTCAGNTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCG
+
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
@r2036
TGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTA
+
E!73A(21.<(E""9(A8;:0DBH8@BG"AH@78D$@?/G!<:1-69;"4:9#B.3)CF:A;2*1F/?>E+'D/>=D&,%*:6+1F..+<%'*/H6'6FEADFB>F:<0#42-+7B)B0.
@r2037
NGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACC
+
"C-A/>*)*2E'F#D=GD#2/.4EC?G;'E!.>@*C"A980+?2'%0@2
@r2038
TCTGGATTCTCCTGTCAGTTAGCTTTGGTGGCGTGNGGCAGTTGTAG
+
-$?!3;B>%#8?D5>"@-7,=<)2<??77'<<&0;84F<A92"D#!-
@r2039
NAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGNAATATTTGTATGCCGACTCTATATCTATACCTTNATCTACATAAACACCTTCGTGAT
+
#%+5:;>5C$44E%5'25E<-:FG+:C="+A6!F?(1AC-C5#@"#A>>H(387%GA'8F<483%9/"3*G1.>B<)6/H+9:@CC&$.8)%&;@A<3>9G6G6H/;-4","$)=$D=:DF+B#-.2;2)@,#4B5*
@r2040
GTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCA
+
$*5(=,FB&.)-G%E9?3+9!""?'3>/D,.:<66H(G5A&4$30D+4(+8;H*.C4BH:(E:=H;*,>EB'7
@r2041
GGCTTCCTTTCCATTAACAAACTTTCGCAGTAAANCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGC
+
5>),F3>)=;G?H9!'D6F%$')6!:/H:;BE4'<4/=C<@,2(1F0=F=;-CE<+1?$&'!D)$;&%:)*(46>9":
@r2042
CNGNCATCAAANNTGANCTGNCAGNGATTGTTCACCGTGGTGAGTTTGTCT
+
*%(%""'*(#$"!(*)!&#'%"#*+&&("(+("#'%&#'$&%$#&&""("(
@r2043
AGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGC
+
9($;E"H!1D$;<<3F3"?(#>"E"=1@&9F.%&3C(>#F1B+D>0+?+/?1,C=,-67FG5F:832
@r2044
CCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATC
+
3*G@"+/=;+151H-HE6-523/H(<<!1&;%>E-5"!!CB4
@r2045
GCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTG
+
.@6$/)%D%*>2H?/6%8,<C<%6.<HB0:<G#%31B92'E9F/4)%&>11H'.B%/&''0*05B+32BHB/@8G#&;G"1+.6""
@r2046
TAATCTGGAGGCGANGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCT
+
D@635%#+D.*!66!!#F3.5D!#B"'),7G=8E"0("1(D@E27=C6G*;7;E7F2/%022-$)GC<H'=@
@r2047
AGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTG
+
/%D&C?!<4(9:/.:=(ABEB6!!'$+'#=/-57$H+GG4G,E&DAE;51GHDG;<.8E@!;")A;%(HD)G:94G1/36$*$!7F9,.#+"HEF+A',0.C""!?24E2?9:</'>7'<G6D,>/$E=FD/$9"27*(=9>2:(BA4+"5C7C)>>(7'?3$=#?+6F@=*D$=!.=3=(ACDH/(G4?*7#/1#G74!AE=CC$8.=#6861'
@r2048
TTTNCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGCGTGTCCTGNCCGGCAGTTTCATCCGTGTCATCNAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTC
+
B%(9F"E6;>5F@+0:/&'>,=#-=(($8@>&@:C?%!*+0"<6>!6*8*(FG)-@,D?G2+=)DB8-%.B$HF;*(G+"HH08@$%@AG6"$@4C9-%>FC<*816'?2&&/#?438-DA/E?$H
@r2049
TGATAACCGGCATATTCGCGCANCGACGTCATGCCGTCCGGCCCCAGAANGGTGGG
+
0-@.H9.%02*G"2#A)A58<?E#215E?@4(.0$GH@)00C:A2;979D$'2#9)
@r2050
GTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACAAAGCGGAACTTAT
+
A'(1,H0<&*;<G%)4/4%?#ACD4$5-.'6@.924<<:D@4/@A,09..ED1;B.F=/6/&<-'
@r2051
GCAAAANACTACGGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCT
+
(/+7)/,3E9<(2-::E.%5$;B>F-G01.;E8:*,-@6?,?%H<EE-8"-8##B!(#A0)9AD2DD-@H'7;"F07&!,#+6;1$-!7.<!;'8$7)
@r2052
TCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATNGATCCACTCGTTATTCTCGGACGAGTGTTCNGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTNTCTGGGTTGGACTTCTGCTTTNAAGCCCAGATAACTGGCCTGAATAT
+
-)7<0AC6!AG%*-A9H/"2;*-D#-FA&5=,#3F06A417/0F=1GA@7$C*"9%3AF8)+!137)G*38EG$.BBB=)1#/='75*16+(/--4D)D->+!51H&/>$@/%A57!%-.2'FG61,@$,56("*>B9?D!!$3G09"4'8.C!6;%.-#H:73/'.*#"&=$EDC.06%4&@H1";
@r2053
CAGNATATTTGCTNTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGT
+
#('"++)+$('*!+*+#++###&('(#&)!)+*%&&'!&$)'(!!"!$+)!!+&$"+#!&"'$&++$*%"(*)$(+"'*$*
@r2054
GACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGANGGATCTAGAATATGATCAAAGATAGAAAATTACGACGCTTATCGGAAGTNAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGNCAGGTCATTGGCAACNGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTNTCATGCAAAAAATATGTA
+
,/EB5&1A$H%&4:C?F-3"!)C*/DH@650-%$D+?$AB<?8144>HF(-E=6*''#G)B<@@4H:E:3,<6G%A;.=)D-/9;$.,C-;#&$6>35<F6=>7AB@A8D+<'@(<8A@"*(-H'FBDB(;,;D?/.G!/<DH-=F9/7"A3*">6(*#A5::%A>2C0&9EFB6%"FBH6&?;<F3H6C1%@'=6(+5*)*.HB:G&52,'!=?0)4A<E&.-++8'9=A+:(./8'455,18):6C,C@1D0<=<E,3,7/811"@<DG.=%"45*0"1%)+)B8"85F-008'?>#02/=#/+HH-<(@961?,?-':A8+%6&6
@r2055
GATGGCATNCGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGNATTCAGCAACANCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAA
+
6E*<2<4;@+@$@"@:"'0F15=3>$=#$>1+83=3+;86(?B3$?%&*,CG717!3/-G%6>'>H<6@'24A1F3(2'HD0#$!G(5/<6,:-D0='@G0;G<3&097>-34=$09%26?/5"H<$-<D"50!!G&0GG2+8@<6%@A30"AH:
@r2056
GNGNCNCGGNNTNANCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCN
+
$*&%%!$*(!"%)((+('$#$#!"'"%##)($+'(%!'%$&'%+*()$&+"+)*)"*&"%&%&(&&")&$"&$%')))(('#+'(%))$
@r2057
TCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACNATTCAAAACTCGCG
+
!.:*3(0="CB?A:/4/B<):!/"&@;"%6FA2*2E)3..5H-1EE)0?7+)?5:GE3
@r2058
AAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGGTGAAGCCAN
+
7(C-!;G4H6A?B!"&"9BC4-H8E:)B3E<B?''A8'A6B#>10@@>D28D?).*@'&;%11>"5
@r2059
GTNTCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTANATAAGTTATTCTCCTGGCTTCA
+
"('+"**()!%+%$#")%'(&&($%*#"&(%"+%#()&*'))()'**%*%'#'$)!"&!)#!#%'!*'$('
@r2060
NGACGNCACGNCTGNNACGNANCANNTNTTTNANNATAAANNANNNCTNNNNTNNTNNNTNTNTGNNNNCATNNCNTGGAANAGCAGNNNGNTNANN
+
!#$##"""!!!$$$"$##"!$$$"!##"""!!$"!"$"$"$!!!!###"!!#!"!"!""$!$$##"!#"!##!!$!##$!$$$$$#$"!!!"$""$$
@r2061
NAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCC
+
-5@88.>##HA$D@+A'!+4',C2@.=A+%@-6?.:3%8H?3*?;-D+.)9H)-5B!#6;/G0E+,<(
@r2062
NTCTTGCGNTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCANAATATGTATCAATGCAGNATTTTAGCAAGTGC
+
!*+*((&!&%##$)!"("'&+&*%!'&+"(*%")'#%+"'#)%)"*"+&+%!*#'%)(&%)#+!&*)%#(*"!$!('&+$)$"+$&
@r2063
GATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAANGTGCATATCAAGCAGATCATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTC
+
E))2$+A#-42%+-G>#3(F-<B2@44:A&AG2F8C&<&58#*C"E/-/;)@GCD>>BCC391?C)%9<&28.)B-<FD.F1:6$:"=!0?-E,.('H600&(=A.%E2DC.4*3!&.F4CA&?:7#H#1!EB!1E%:66G',2=:$;2H:"E1:!/-3<C-?61F6.)>/02():%75#21&4@B?G-)E/-$/&'=D
@r2064
TAAATACCNGGNTNCTGTTCCGNATGAAAGCGGTTCGCGACGAGTAGANGCAATTAGGGTTTCTCCGCNA
+
($'!**$($)$$&!***(%'"))+&(+"*)*"!!$#&'%!""")*'$%++#+&('!++*$%*%+$##"&'
@r2065
GCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCANCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCNGTTTAATATCCNGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTCGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTNTNCTGCAGGTGCCGTCGAACTNTAACCCGCAGACGCGGCAATAC
+
@:0?AE44GEE2?('(9,3*C(5H*"3,D<#'$D5>6-+$%!B>0?07'.(8&#'+B)5@(:C',%-?H544,%%C,><<7C$?"915)221+6G=!;BHE8.@H21&->FA4></();E-?!5$/EA6$%(2E*%5=#0$.@9(H2E4,+8!A=0@C;6/."8B?08<#D&&>8:A3"=,*%)D(@(=5<-*?2<D!#40BFB(;"B%/&?.+,B5@0F5:2G<6*:G"$C'EDEF1.A!:3:D,F7>)<.):".?CF99?",CE/=F;B.1$-6.3.04$%+5'4<%4H<(E5,#E@,DF53$7,"+F,$3(1DE+FA9)3=?,-5D-+++?<G=>C+!,2/0E")%<8<)9E<G2
@r2066
GGAANGGTANGCATGCTGGGTGCGGGGAAGTCGTGAAAGAAAAGAAGTGAGC
+
D&?4(%E#9%<&<,G-2:6AF9..C($-7H?51()GE*;*&.:7:!H71-;.
@r2067
NTTCTAGTACGTGAGCGTNGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATNCC
+
&%)""(*%$%)*"+%%#'&!!)+')#"*&$)$'%#"*"+('')"#+&$*+$#!*
@r2068
CGATATCAGACCACTTCATTTCGCATANATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTC
+
'C7+>(738-)4E1=&!F%F6"#!(-E4%?@?<$2>78!+FG!:>6,((,4-%B;E4!?#)?'>,@#037("$%+
@r2069
ATAGGGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAG
+
%(*)!++')%&'+&&''$#$##))*#$*)$(*!**&*&!"#!)#%+"($%#(!)"'')!()&(
@r2070
ATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAANCGACTTAAATGCATATGNTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAGTGGATGG
+
6H+!$=%4.)H&<*113F48:'5BG3*-0BC9!!C#:H.86/+/A;G204B5$2G("?*42+876##9-F">?2918".6D-;).G436'-7)0/)<%0:%1ABA0D8B6++=7#"./C
@r2071
NGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGC
+
617#)+BH1E;C#*:.++"@857+E&5%51>84DABE2F%#>*3:?0<DAD1C:C($-?5&.');"7%D6F!7BEF)4H*)F:=!9H+9/:!%@H?B@#98+D7,
@r2072
GGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGATGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACAT
+
74.2952!.$CA;;<>%@6=096,5**5>+;HB.++&>HH@)-0C20C7''5H+2)=44@%..H&!D8#8*?G.<.4350)-@%C0#C@<./?<8$B>(4<D%&/803/4,.%&58#&<16$!3;C%=(9(E-E#G+:C54,(%/DD?BEG9A+:"!:G/"3G3A&"?1FB+:0&"%)A!-G57--@(A$H;A/
@r2073
CAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCTGCATTTTGGAATAACCGA
+
1'6=6EE-H@CB#F03C3$(8,;55'A31552,F$E!HB)$6<1<17:3##;A9=?:9$07,F76:/?C5!5AC&@:
@r2074
CTTTGGCGGCTTCCTNTCCCTTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCNTGGTAAGCACGCNGGAGGGGGAAAGATATT
+
6+E-AFG9?$-<3.A.?="#C=F$A;./'=->-EEAA$>)$B%*;4;5&C">G-61FGH9)1E3.F.:,B;A17$A4?=/(C$3&5A-,#&#:?<8=(*5B7'.;>B!&H6D08'$D,G?:D>"#F!<,D;@%"?E5(H=8#%DD
@r2075
TCANTTGNNGNNANNAAGAANAGTCTCNCAGATGACGAATCATTGGGATNCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCNGGCCGACCACATCC
+
&$("%*#%#*(%$#%)"%&*!)*!+%!('")!)"#("'$%"'!!"#()!)&')%)*%'')#!"(%"('!$$!#+%#&+)&##"'$(&'&'($%$##+(%*%+$)&&#$'+)))""'#)&%
@r2076
TTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGAAGCGTACCGGGATCGATGTGAGAGCTGTCNAACAGGGGGATGATGCGTGGCACAAATTACGG
+
<!C#3*0.F4:=)95D9(",7&8*!,5?A2<34DH@1C!GH*@!77*>;&!;;207A!3"A5&,B=CC1&>2*A&!H97/.5=CA6?9-FCG46=&C#>-DGE"9&0E&2.A!A43@5B2#?"/:E!
@r2077
ACATAAAACCGGNATGGGCGCTTGCCAACGACATGAACTG
+
G(-.H(6:0/2"8D@25?8;.2C:@17B*6?$';243'+)
@r2078
GTCGCTGAGACGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTANGCTGCCTGCACNGTTCACC
+
2?FEH2535*B>:F0$5B(2'+'4&6,0"/.!6;C+@%:G97B)0:G1:='$A>1H#=:!.,.&"!.H81$5,6%82E=E@7D<,CG.H'$=(B
@r2079
TTGGATGGGAGTAAGCGTATTGNTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGNTATCAAGCA
+
+*A'7(9D57%<866G3B0.!E%&EAH>!DC3%)D/>2#'&C1&+*;!-;H7FG?"?<*?.6?<9C"5&-7?.2#","7.0-<B%#43#3"*1/+%H.6;2C6D?)
@r2080
AATATTTGGGTAGTTAGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGA
+
-3,@"62).>*6**:&1CE;50>%?A;/'&@!*CG*!1.0:6#C:?4E%7*+B@4("%0
@r2081
ACCTGCGCTTAGAACCTTTACTAAAGGTGATTCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTC
+
B0(=**=%G%>)?!+/$+&)B&);:/,6.0-(HD4#8;@'+9!%!8,1!=">H-0$9.!1$-G5+*:+%EC+A?(40**5828C-(><7(A3%A"416..C>=1&>A>1D!H0?G:D!C.2@6
@r2082
CTGAATCGCAAACCGAAATCACGAGTAGAAANCGCACTAAATCCGATAGACCTTACAGTGCTGG
+
;?,-,@415&@1HB@$*(D%/3&)!8C)8HCC%+,4AE1=;):4/?,6:2&0@*B=;0DCB:!,
@r2083
GCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTGGGGNTNCTGATNCGCTTCGGGCTGACCATCCGGAAC
+
"5/)54'<1*>A>0C72&6%:6:E%;<#07,,$3/#B+':G.DG.&2D0=7=9#*9D<=G'$C/#;69/C*G/2:5!;.CE21+6?E@DF/
@r2084
ATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGNAAACGTAATGCACGT
+
10D&H;.*652G.0*:<9-)F-3@A?;*##CHB.*)1&<>B?7FG6=,."$+/D#76-/6E3637=9$28D"?2C!8>=79BC)!?;,H2G+1F(/$'+
@r2085
NTGTCTGTTATNAGCGAGGAGCGGAAGTTAACNCTTATGAAANATGGCTACGAAGTCCGTGGCTATCTATCGACTTATTAGTACTTGAAACGCT
+
%+(%'!%&#'*(#((%$')"#!&!!'+((#&$+)!&#**"!'(&%$(#+)&'#'(&*))!*+'+$)+&*'$!"%!!("!"#+()##!#+%$&$+
@r2086
AACCATTTNNCACACGTGCGACCTGTCCATGAATTTCTGAAAGAGTTACCCCGCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGNTTATCGATTTGGCCATACTACTAACTCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGNTTAATTTGCTGAGANTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATCTCAGGGAGTTGACNGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTNCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGNATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATNTTTTTCTACTNCAGGAATN
+
)**%&)&)'$+"(")%$+"!$%)!+*$)%%&((&$'#)#!%($#%+*"))(%)")%%#'+"(&#"!!)*!))!!$&&##"+!'!+)!!)))'$&"%(%+#!(!+"+&%*')$(('("&*(!)%#!!+'"&#%(#))+*#**!%$&%$(&%#+&*"&)&('$(!'!+!($"))#'&+)&#'+%!(!*((&"$&*+%!$"$"!#"&!%%%"+*"#+'(($*$%%+$*'#"!*#&#'!'$(!!(***&"$#*&"!!)#%(%!"#$*$)*$(#!$$#**#%%(!)+'*%*+&!(*'&*"%+#%#&!+%+((*&(&!+#('"(*"$%*'+'$$(*(##++""""(&&&&"$&(!'%'"*#)(!$)%!&&++(#$()()++'"$"*'##%""&!'&'%(!**$*%!++*+#)"!#+"""!(!!'+'$#
@r2087
NNNNANNTGGNTGNTCNCTCNGAAAANCCCNNNNNAAACANTTNAGGNTNTNATNTNNNNCCNCGCATATANNNGNCTNCANAG
+
"#"$$$$$!$""""$$"#!$!$$#"$#$$$#""!"##$##""$!$##$"#"###"$#""!#!"#!!!!$""!!""#!$#$"!"$
@r2088
GTTAGCCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGAT
+
14)?->:A-'0G#:#4#+CD;4@@9!2F,=FF;#@&85GH6%:!84*E)#B,@<08%*=:(,-
@r2089
NNGNTCCGCCTACCTTTCACAAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTNGGGAATA
+
'"##%+(+%!$'$*$)')'#+&*#%''$+$'()%**'(#'(&&"+#"+%**'**'$!#%*#""*)&$&$$$+*%&!%*%$+'#(!#*(+%*$)+*!
@r2090
TATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCAATGTAGTGGCGGAAAAGGAGATAGCNAATGCTTACGATAACGTAAGGAATTATT
+
F+;92B:=9%7560HE0E#G&25>?H<2<?!=7:E:-9#6GC1-$0:2B&D';?7.4=H)%@>EB>*0:41@,!2,3:C($;%!/)G,2C"<2E:!91"%4"/%:<!=B6A
@r2091
TCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCC
+
6(4/7273;.7<'%';@(&7A5.B.69;)(>%B1">+/3."G./"+FCDE
@r2092
GGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGA
+
7!C2%H9/%H)(=*36G06&&=<4'@?/=F,19$7;1=+=$2>.0$&(D2<=$1
@r2093
NANANNACACCNATGNTGTATGCATTNATNNNCATGCATTCNATCNATTGTTATCTAN
+
!#**!")$$(&#''#")*%()((%)'!("&%$%)*'++$**()+)))%$(*+)#*'#$
@r2094
AANNNGCGNANGAATATNANNTTNANNNNTGNNNCTGNGCNNNNGGTNANGTNGCTNCGNNNTC
+
"#!#!!#""#"!#"#"#"!!$!#!!$$""!#"!#!"!$$""#!!$##!#$$""#$!#$#!!"##
@r2095
TGAAATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGA
+
'")!<2E;"&=1>+</DB*%))+8B/40$%72E&$#4+:00&/C9>3',%<210#0D(-A6(7C%DA<6(!A!-!3/@@'.;-.9E#@%1;7>/-)@#'B*2%B!0C,4ABF9>4,=
@r2096
CTAGATNAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCT
+
)29!'-1(E"@6=E*9<)3&#?),?64B97E!"1@(A#80<&-1<C-B)-0/7
@r2097
CGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTNGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCA
+
0F9&6#)A!%7CD47AC5"-D4<>H&2'B8E6#%''/#A:3?A2$'#26==-!G);)/5'4/+#52!675)B+;@G1C<$-'@B#&,;!'-#;
@r2098
GTTCAAGTAAAGATTCGGAANGGCAGCCAGCAACAGGCCACCCTGNAATGGCATATTGCATGGTGTGCTCC
+
?1-FH@@%/0/>78><8H"&E6/=>&,@;0$96%>3/CHF>183.(?,:85'5F$?<=21*?#&'*5/8)F
@r2099
GAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATT
+
0.9?;(2*#.7F(!$&D6;"H'43E!B+.@>*.9+7F5%9;6<>2/=FE6(&211/=)$+D>6"9D%6))8A:/&#BG.4,,3,*!C(D::&6ED=#6&%"(8>
@r2100
TGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTT
+
B-BD<<C&!F.82&$3&3D!;(&+*23/FHEC$B+=H/$>04%7G,0<E/7,6=;'#<&(5*"::1=G<",)/;+&BC6<951)6
@r2101
AAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAG
+
;;?9="0B)D4B5&'%*)+4BA1>-A-!F@>7)9;DC2<*H>*5$-F+"'8'/,;?!'5<-1!HFF57378'4@4,*!9,(>30*2?4%C;,=(@/50:!.(#B<;;.#1?1A9:9$:2B
@r2102
NGGNCGTTGNNAATCNTGCNNCACTCCGTGCCGCCGGACTGCGTGATGTTANTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCGCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCC
+
"!)"%%%"(!"*$!"!"%*&#+&#%$)"++'&*!"*"(')++*$(#*'$*!'!"$&"+"$)*&&*!*+'&&!"%%('%**!*"'*)&&&'$"&$)%('"$!&++'*!$$)#*(!*&"*$*'"!%&(%$*"&&#)%*)')%+&#$)+&*#%%"(#+*%!&'$'&)(*)$
@r2103
CCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTAATGCAGNTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAACTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCT
+
+($)(")*'!&!$'#'#%%))++)*!)#+'(+&)!%**"#!!!((+%*!%*()!')#*&!&$*!!%"(*!##!$'))!&%##$)(&')&##(*($!*&#"$$++###%!#*'$"%%%#"$(+)%&!)($(&*&)$"!"#!#"'#+#*&*'&+#$('&%))'%&*(&&+!""%$)")&())**()%&"(#"''&%#')'++%&'*%(&$%$)$('#)#''#$**)+'
@r2104
TNNGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAAC
+
##!+(()#&)$($)#!$'("+$*)))()"+%&*%+)*)&&'!%"!#(&$+*&!"%)*&"'%
@r2105
TTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCNCGAACTGACCATAACCA
+
@78FA/'+,"&A%"5;:20',C6)F$:4!$),A5%&28,)7C(9@)2;#3(E75>).8A=:=:B9
@r2106
CTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAANTATCACTTCGACAGAAANGTTAGTTGACTATACAGCCAAGCTTGCAGAANCGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACA
+
D<(3B"/A(,E)/CH333*($:5'7(:$*1:./#"A%/?%>*+,+A%G+#%!-E-1;)=@8$;"-#$0+!?DG04##,=3<A38@A#(C:=FB6%>E&,F-<E?G:&:G;,FC.%A&#?G+<C0<?4+581A6FEH<&"F@@8B)H7:2&@G-H4C($"+;%E$-.2&95-,0,:.E;6
@r2107
CGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAA
+
54,7?0"A4D?9G()4=6;<1/BEGB>(%1#&;68'FF*?0/5H2"77
@r2108
CGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCA
+
2F891AA921;+F839"#=/BF"5F?/A,05D"8#E,$6C>G9&DF;5%(!4&.0*3C&A29!4?*H5=9DG("'2:719D!@$!,%>G@@0&9FG8BDA#G)D=@;GE,1%$/E359:
@r2109
ATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCNCGTTTTTGTTTCGCTTA
+
,G/9!$,()/?.',D,(:")8)F(GF&/48G7@4/@(9#80;6EFHDD.&<A'5F#,9$;>-C*40($3#&.?G(*>F;<A$!.)C5#AA'9E>B(BE
@r2110
NTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACCACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGC
+
%>!3(/((:1,E#E712<6=2H7C3D@F)64/D1:8&)H'8.@.)15!6<=5E?G/-@#-;#!,=$A'99C<:45H:#;$*0B68F)<-%?7**G0,#HE=%B6&B5%?5:.+G7F4)/6"*"2.5?%>B48G,04-:H335':=&9:8('H$C&".E=$+)BG$&>*42#"/A'5"A#.A>'==%5G*7/D/8;2=76#6>((#/#<-E>6)4?0G$#0B25110H&F%?H/746
@r2111
NCNCANNAANTTCNGNNTNATGANGNCANAAANNNGTNCANNGNTTN
+
"#""$!$!"$"#!"####!$##$!!"!#$#$$######$$"$$!##"
@r2112
GGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAANGAAGNAAAA
+
+#!!&$$))('#"++()'%!%)&"$'%$"%'()(('(&%+"%!))!((&$($)+$*&))"*')*($
@r2113
TCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTTCCGATACTGCTGACCCAGCCA
+
>&.&H1@',!B5(+=$A;G$%H%/%@72#=".29B)>87/H@94-2>0&89"--2A1/(,,297#B.1;,-",;G9)%$C;.*'$GD:G://!&!+2:<H3$A9"EC,6#)A,#.;B9-4:H',(F+GB%=:>*:&C$1&/%#)$!/.)HA00&#7#E%=B3<%!E;/=G
@r2114
NGGNNGTAGAAAAAAATAAGGCATTCCTANGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTANCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAANGTTAAAATTGGTTTTGTAGGTCAAA
+
!&(#%%+&!*"+%""'*&#+%$')&!($*('#'''$(+%%(()"'+*(#($"&(+%('%)*("#+&*'%'$(%%+)*+$(!+"&))!'&&&#$)!('!)&(+$*$+!&+%)!+('!"+%#""*!$!'%"&+"+#)('&%+!'"$
@r2115
CCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCATCATNGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTANCTTTTGCCAGACGCGACCAGTCAACGTCTGAAATCGGA
+
60/BH8'391CDGG;3>1E@=?>C9;;7!;7D8%A0<1)9-!.,%A=:3@=0*H7H(F4412879G@@='2F8A@>+5G/%CBEH4),52$4,>77?>@E=D-B?B)F"$9;9#:7@'<<0?A1G$D<#<;9+C4#
@r2116
AATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATNCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTGTTCCAGCGGCGTCTGCAGCCGTTCGNAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCNGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGC
+
*+(!#*(&)'!$$!!"*!++((!*%&'")(#("#+$*+&"()!'*!&$%'"+$&!($'"$!%*+"+)+%'*!+#('#+!%"&+!$"%!)&)!#)""%%$"!%"!#(#&#))(*$(%'#)%*!+!!+$$&#))**+$+#$+('(!!#+!%))*!%!+")(++)*'+)"&!%!$)"#$""")&)"$&"')(+%"%'%'*&'!&'"(!&&)%*(%&'+''#$%*'*+*#*&*#)%)#("'%
@r2117
TCGCGGATCGCAGGTGAAATTNCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCACTGGATGAA
+
./4>10.:<AH074F@@CBG:;)B9>14=/(2+1)F$CFG&DB""6&:%$3">&3B(>*@D7)#24,%"@F;"A22;AAB4-(%?!<*42(-:''B7*>*4GG"1$)0;,)3,"*>74#)#HE(@EA<6&08#5-?(+$GH(13+#9
@r2118
CNGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGC
+
#"++#')*%*&')!&*$*'%%'()"&"%($!'%*&!($#(&$(("&%*+)+*''$+()'"#*(#&$)%$%"*)($)'!("&%++"%+$!&+#$!&'''%%!+#++%"*!)")*+'$%)#*'$'&'#%&)(+""*()++'*#+%)%$$%$+!&#*'
@r2119
AACAGTNCAGCGTGAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCAGT
+
(,$AE>D26#0";!?&=>9<(<D7'2'3'&%<40AF?4?"*%3*E#EFH.8A5'&C
@r2120
GCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCA
+
9@-H?(5B,<FF&</87*EF&?<!53;!/#20;/&*.!H2&5%/8A09*0/G4188@'E1&(9B8;$$2(;-4C")4
@r2121
ANGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAG
+
FB<0"%E1.:/&#98:.:,'9*4?0081,"6,#B*AF(15,4=$2,E!,H2>.%
@r2122
CCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACCGCTCCGCACGGATGCATTCATTCAGTGNTTCNTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGC
+
?#F9%8;>'=<99)5C<C%>HG;.D,*.03<'<$#E7+),!!@3.5C-,AE,F&<C#(<()'F2E"%?6:74F$@:*0$6D,5D&2DBA6C%#931'5,4;'E2@*)9H">E;+,=*>+/.
@r2123
GACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCANCGGCACAGCCGGGCGATGTGCTG
+
D77"H),!.?(0.@5:!C%/.-E.E6DAEG?:27A+5..;D2;,<A4)A+4,<!#/+3)5=(?+:<9;7?2!5'1*!86&"E2F*H(=,%D+*=';(6,;-<.8@63/)-<-<5>F,C";*01&7:"$6>0'646=834!85<**':3-C(F"/F'A*D7'+@(HE+)H/(D<1/
@r2124
CAGATGANCCTCTGGTTCATCGAATAAAACTAATGACTTTTNGCCAACGACA
+
@0,&;D!E.'1.724>D2*.7*C#C@H+G8B<,E<AD9+&63,$,<:C/='8
@r2125
ACTNACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCA
+
""#")))+)''+)*)+((+%"')&#**%*+#"%&+"&&+%!&$+!+#!'&)%'!)($$+!)%'!'$(&$"(&''
@r2126
TCCTGCCTCCAGTTCGNCGGGCATTCAACATAAAAACTGCTAGCACCCGGAGTTCNGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACC
+
F==%)(:&&3=8:>A&.F?:%<0+56;<=(F6C):6F$30152=B($C6BD%20&G$":)@C48!,<C6)1/#7E?.=B>99B?5D)01""3<.BH5:'../+>/>6:=4H#BD&?1B1A:63'%9:0$1H3#$A
@r2127
TCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAG
+
246'1$7/59?';;F/2F'8@0"629"&==$5F>=C7::6;&<!C.5/C;4?@@3%)9&362/?B$;,F>432+H<6-F+!7:@A75B4DAA0<C=)<D0AG@E-=++=:#<-H7;<B+
@r2128
TCCACGCAGGTCTCANAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGNACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCC
+
,*!:97>)=E=0'6$H;4!5-:;&;%8DA*:3!)@A9*@!,G9&DAH59.;%=:"'1#?9.;3H+=69!AHE!B6#5(7C:5&<E-G&<9D>1">?(657850E=0!*<D/#&7&<?2(F"7*EB*;4G>+%"
@r2129
TTTCNGNCAGCGTAGNCAGTACAAAGGAGGCACTCACCGCGCTCAGTTC
+
$$)$)&#%!"(")!$%'&++(%*"#*&#!%%&+)+%+!!+)&"!'$"**
@r2130
CGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGT
+
C654&&,<(,@8D4@::3C'86!8!33FC,D.(#@D/22:>63E$@C+$!(>A19G$*)9C7+2(F*E7B/(CE$<4H'"3
@r2131
GTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGTAGACACCGCTNAACGGGATTATTTCACCCTCAGAGAGAGGCTGAACACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATT
+
3&C;>>?/4'1%.9</(C>;E?AH3<0<<.@3(1B-@,:&1#,9#;G3&26);>3#/!A;B"5GG(@80.#EA<>H<:=E0.%.)&E95:!D8#1%74<%+&&6=>*;62D/*-@HA7@C.-5""=3%(3/$E?2$>
@r2132
AGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCGAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGNTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGANTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTG
+
-+/?(.:<@99$1H<62HBB4%4(318C8C%94!%?&1%>:"@/+1C41'*')E$9631DE2.:'AG&76-9%.A(&,H=!)(EDDFE?2G9'H.)?*>=:>67<#C$?FD'@!H,D9+.@389+13:!C:2BH53=367CBD:1C",@>&61#$#D)D#"C7((E17+4?B#3E5H202-+.EE';<H%%*/>*8!4?EG1>0()=,C>E3&5:E9!&40B*&52)4:7+.
@r2133
TTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGC
+
.7=.,0;"BG-##=-?(8EA#43:&9&(1@4@A3%/.&+?=<D8?/E@D;+3E0G2#'5;)(!,.$744-9$=H8+B-D"@()%@(11E)&''1!';<445.(D$/>
@r2134
ACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATNGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAA
+
.%328<HH'FA*D#@&&>B,BH=>>#37(/;9';=2/$;"'#D;@)G&,G91/A)C.)#=>1#@1H<>3.$>%C+(3#7!1%BH>=B?@E3'*'")60
@r2135
GGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACT
+
'8+3:;=9B5>CGBHD#&,/";HF00!?H(%7C?'*/G7)4,((5>(>=.
@r2136
TGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCT
+
904A+D"@CFH)5;-*@5H,(A=HBDHGB%9/;:&<9$753>E7;A-?7H65C7=33,518/8'A;/&%
@r2137
NNGGATNTCNGGNANNCGGAGANTCAGNTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCGGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAG
+
#!$%%*")#*(**)+(**!#!*(#+*#()%$+'("$$**#)*!'%#'(+'*'%#&#"'')(!(!(&%$""&"!!*#)$+("(%$*!+$!++"*&&'&$#)
@r2138
GAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAA
+
D33<3!FH@#A/+B0#60?5'C%;7"E-"5<$>:G.1&11;H)-<!/B=-=0=(+"B4A493!"GD?*8&/?,E""#+!-'
@r2139
NGTCNNCNCGCCGGGCTGTGGCTCATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCAGGCGATGTTATTGANATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCG
+
""!&&$'%"*''+%+!#*+)#'$'$*(%'+%$'))%!$+!(#"##$%'%"&#+#*%&%$(*()#$+'#&!#%$&($"*"%&(%#(+)')(+"&!'$%"(#&$(#)&*#$#)&(%#!''&"'(#!'*"""&!&$*"')+')()%%&"$)#$('$**'&%#'!%*+&#!!!'!'%'!$!#&)!*")'+)'!&)#%
@r2140
AACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGA
+
G7!624586-EA!6*5!E2.&>!C!+A<8=.BE6A#AFE4'<(.>;"&D*='2G;4!"6@A%5G.0'(D6&.H>FD"&'/49;)"3
@r2141
ATACCGCGAAAGCAGCAGATTNATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCNCTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCA
+
(,&)B2@(>1?>,C%-;;B(1#49C?6&47@:+*0C5H*)@EH&?2H"+(8.B512-A5?4D<1E*1%)5-331)56#<!4;!2)<5C)C2#7)D?E+3)$&6='BE5,:?2'>0D<7F
@r2142
CGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGNGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGG
+
/!A>G4F0)G2E6'B&74"+A,E*F,A%.G@F&78>>3$F",7"+7C>3<,01H%09C""F9F=/#3#1>!?-8%.6GC'&D/%+3A&H?)''>G.H.*/<;%.%*#,?A/$3!
@r2143
TCAGTGTTGATCTGATTAACTNGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCANTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTC
+
CA66C2)9#&F5=%<B7?69G:6:D8*!=?H3-;:;*<94#E-H28.3G!.E30"%+-E;*320='2;37(,1:BF/"G.H&("842>27+9G!
@r2144
GAGCGTTTTATCCCGGTGCTTTTTTCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGC
+
=16G@-E.6/-C@(6B;@.1'?:#=:,1-3B(+:&&3&4($*01,/C>D+%>28-A??9$<?>?B"#71,60<@,H,0<"E$F7F+$H9,C9++:H<!6%GF&91+?>($B&3%>".D";+
@r2145
GTGAATGCAAAGAAGATAACCGCTTCNGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGT
+
2D%GH0;G9<6>72C%7@9G1,?<#-%65)?;;&@3?$@D?C:/%;,?)*"*3(-<8'6D:H'3%>>H5&5?7,8:7F@(;78:)")H&1
@r2146
CAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTC
+
E%$CA2H+D9F5'<+!#"H=C6F4G)>E;A.H?$E?1E;721.GA0&HF9"'96F)0
@r2147
TCAGAGAANGAGACCGCGACTGACCATGTATCTCGTGCGGAAC
+
0=,4@2BDG#'3$7/%,H))%22>0&%@1H;8CC#$;>+A:7-
@r2148
CGGTGTACCTCTNTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTC
+
E9@/?4<,97F+A6(.C&,.F")8:?A?9B-8H>*&4%AA$<+11B.F1+-!1)@8)$3$#E=1@8C<.A4&./(46-,*C(:
@r2149
TACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCANACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCNACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCNGGCACTGGCCAAACAGCTCCCGGCGTTTCGTCAGAAACTNAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCG
+
6@&E:1'@)'7H+A50,!.3""+A<&F3:#%!9!80E#A46&D4H=/9%00/#<$C/0(6*$:$;@A8?D-+2H&0%3)EF?@3)ECD:-EC">87&%C9.>A@?=3;#E<=6.F+/0!)B=9,%'B<<CF@F4:.:,*@?:3!3CAE4&)@<C48-.)$<">)E<G7"05-A8!&))10<F!+*))B1'<!8:6@?"=C>$C$'AF9(E(,?G##:):,&F&A1-5G?1G/)%0',<=/5:G<6.G&>"15B6E$$2H93?97G"A-?.E$33!453<B768-C%(*"!E!)351;HD),5#B@H7:16<'EAH;;/#24"$A,7A):2?,+:<AC66,D@745&<(8,)&)4
@r2150
CATAACAGACATTCACTACAGTTATGGCGGAAAGGTCTGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAG
+
)+#()&)%%%"!&((*%('$)'!$&(*+"#$#%*)$+##$)$%&"#+'+&+#!"!'#'$!($*%$%!+*')'%"#
@r2151
NTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAA
+
,AC@/:+2+E<'3A;GD>-!8<',4+2B3>/-#E;3:>09-=!G!.):66'*!#D,'#6+,29929??AG<,(<9"0*=
@r2152
CAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCG
+
?-5H:H2:9C=*!?>D#0F;9G7;:5+5/:33!:E=$1"4B;1'5,39<F-@B&0&!=","#5.>#.,.D#**!$6!55
@r2153
TTTGATNCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTNTTTATGCTGTTGTTTTTT
+
#%%$('%(+&&(*#!#)&($"+*(((""(%"$#)!)#+"(*&%*'*$(+)$(%*&'(+")+&
@r2154
CCTGCAGCGTGTTNTATCTCTGCGAGCATAATGCCTGCGTCATCCGCC
+
$*)#(+&(!!+(('#'"&#%*!#%*!*'((*(#%*$$%)&!+%)!*)*
@r2155
AAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCA
+
+&'*'($)&*!#%"%*)$(*"!$&+!!)&*#%+&)(*)('&%+("*'(#"(%$##%(&!)(("'+
@r2156
ACGCTGGAGAAGNATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCA
+
H@69)6C#D):D9A5@-H600971,B/%%-?D$&3),D-:5A)3GH;=)='D,4)G1++0,7"D*=&(F=*%B>%1?*506!29,)7):796?D4:F?(7E
@r2157
GGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGAT
+
<*42-A8>F;,:19@@:&3F)&89G=)?.FA+:<*#:!-!,A@G346F*H,$?43%CH9DB%-ED#,'(*C2?52+C?&9-B6"/@FE-9H,>&49-2DAC-(=>!#-9BA00"7
@r2158
GAACTAATGAATTTATTGGTGAAGGTGACGCATAAATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAG
+
H'4",,7"7.H"=.4DF%"@3;8A''.&*>!F'&,65@&HH,GAC1-<;)H/?=B6:6;";C-*.A':))H:%E:&DD@#-4$HE7=
@r2159
TATCTACCAGTTNTAGACGCTCTTTNATATCTTCAGGAATTATTTTATTGTCATATTGTA
+
251$:!%&(A8945B*'F?G5#/=3240$G=C/$$)!)C8$"=,$85;G+:?3:A6130@
@r2160
GACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCA
+
9579<-2"<"E,.1C>:44D@!"91;C$,$/B>A!"(>?=D;2#HEC*?B#AFA%$;
@r2161
TGCGCAGCCCTNAATNAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGNTCTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCNATGATCCATATAATNTTGAGATAAAGCCAAGGCCAATATCT
+
+@B=$:>>=/F*.64G635HH01$DC>&DG*%H-6(@2,GH>33H329F/$,6>6B/<;8!!(AE<3.!&/1=F.*44%8*"$DC7B,01C82HE>@A,1&/2"B&C?<'=0(7$>(C?H*'2<!./;>;?/'0E4>+52@%A6E3F59%5F;,$@/+)&7F*!H.?@@%#=68>&&C$2$(48133@?)6'#"E&-"(<F$16E?H*5F
@r2162
GCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCG
+
41EEB2:AC<)--#E,;2<?1'#,)!=F!"&D+=379@6#3>H+?*H9"$*&77-7/9@(-B2#A2@C>0EH/##=@!4*#786)*9!
@r2163
CTGCTCAAGACCTTTTATGGCCATTCATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGNCAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCC
+
1883G(,7F/DE(3D5D*C>1("@B:9@!-'G#!8A.220'H=G6#/8'13&8G@F9:H!9">2:%H::8.($8@8-/53"&>@=0D3A5CF#>=!F"1<"@:F=B&F!-92=)D!#;';-6%!D!<.209;!D!
@r2164
CCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACG
+
9%-:3$7%D"@DB!8-:$>14$C-4!G)+)F;FC+7962+>("")=?8?;H
@r2165
ATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCNAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAAC
+
<BC8$.'EC<D+0-?3?@64-;"-G&7?>/*4/%7+&F">B$20*73"G<.:HB!9#>CB?=2'EHG#H#9&9:4')6<->>!!;:E@;D/#,
@r2166
NCNTGNNTCTTCNCNTNACCAGTNTCCNGCNTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCG
+
&(#'(!&"*#*""*""!"(&#)*!'&##*'!+$%#(#+%"&#!+'#)(&)+"$#*%#%%'$*#%'*$"#*%"!(%&&
@r2167
CTTTTTGCTGTCCCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGG
+
=78-&3>.($.;C#$/@7;G3:87;,GF-%06G/?*7D81G$$$!990C0HD,B'3@*7@-6+3H';G)"19;$=02B3G:&)*"-GB5D<*2=&-9,+15)@C/9/GC&;17==5>885.(@<F41D
@r2168
TCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAA
+
&,.A,>F/"D*F@G'65A1EH6+$2;,.;$A;GC6$9-=D--C4F7>=,,"8B-EE,+4F#HD21;2
@r2169
GAAGGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATNCNAACTGTATGCGC
+
('%#+!!")&*+"&%)+'####'%&*#$"')%*"$+#"#**$+'$'#(''*)#*$%'&**'""$$!
@r2170
GTTGTGTANATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAA
+
;<65;:4:/"4BA645:+G*!>1?<<23!.1(=?)B;*%>?C+<"9&F,$@8*#3A"<?+&98,>4=6;G!A-EC$D%!-.H3D9D="0&60D?7:/H-&'#)A,*;#>>.2E/.")#?55,+&6$<"/B!?)405##AEG=%-39@21*H5)8HE;#3=
@r2171
TGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGACGGGTAACCTGCCGCCGCGCCCGTTTAATA
+
'2:5*E5>H!&HDE=>:",F5>:1=3>C*A5<%7G$&#?C;.$E7!C-'??/B"C!":CB43(*#D)D533((#"C#B,H&84B1*,C:1D&<+.,@
@r2172
CCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGANAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGNC
+
)$&$&+"!$&'#$##'#+&)%*&&%!)$+''$'&)"#'(''**&%'''"&"#"(%%)$)%'%)(&+!$$$'%#$")"%&'*$##*($#')!%#"#)("(&!*(&#)#((*$'$(!(*(##)$&#!$"++*+""!$!
@r2173
CTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGAT
+
'3D3-'1*CH+DCE1'(!7E/6'9B?/#E95D"89A'@84!H'B9=:FE2!(C.-3FED.#90;5,'$-G?9154C7/GH<H5BG@$!-)
@r2174
NCCCTAGNGCGTTCGGNTATAATAANNGCGTGCGNGTGNGATGAATGTTATGTAATATTGG
+
!#&$&)**&$))()!*"(()%'"')#$!&!#(&!"$()"&'#'+"&%&')''*##+*&)**
@r2175
NAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATT
+
"),G!)4F>.+6G.G@+2)CD285->.-.".,9#:1E!(:BB853,:3>)$C9!B9542-3<,7H&-<DF%-E5G?!<BB(CH$93$9-!.0#:&F=,#>"7?=B98(0E=D.9
@r2176
CTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGAN
+
(1A/$578(,2HAABHCGA2480720;<"*A/E*HB4>"'A:56%B:19=.3,"'!5DB77-9,(FC1?)+1F.G8%-,#DCFH:D<(A:"7$=#623!%@7)!(%2!0+0$B'A
@r2177
CTTGTGCAAGTTGCCAGGAGGATCTGAAACNTATCAGTAAACAGAGAGGTTCGAAGTGANCGAAATTAACTCTCAGGCACTGCGAGAAGCGGCNGAGCAGGCAATGCATGAC
+
DF?=%."@+0)53>=A&A1@C70.ED>/5&<(5&G@5#H:B9592,8:3#2*+=%C4=.-G==2?02HB-:-,,6$>!,!5*E'A36DDE#=F,11%C-F@!'F>>>E=3D$
@r2178
AAATATCAGCTACGCCGGACAGGGCGTNCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGNGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGNGGCGT
+
:10564G-6-,>+$8$?$AF@"HG@<@+E2@*&G7>C6#5''=&("&AE59!'BH;EF@9*:ACDD+29H:%)*C2<B9*?#D,)31&("!$C$%&B(1&@6;.1-D84'A-!!AF9=H;-F,@4.E!D$E(!#3DE9'8F(62'6;GB!-6%5)8;;+>;8;5#=7$;%.(G=6>D>3/F"3$*A
@r2179
CCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCAGACCGGAGACACCATCGATTCCAGTAAGGTT
+
,;;;D.'&#2:*/:)?0->0@F7F*A*6&&!>$?H!H(&=AA:7D%"481572/+6HG6&9B<(E#=%"
@r2180
TGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCC
+
D?<9;.1";E*7*H"0,#)65H/EC(B#GC,@4!<+0#DHED
@r2181
ATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCANATAACTGGNCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTAT
+
06'(D-,<8936;B=))EB/:G;FC02$':"3#<=H'B%HB:D,8FHC/6B:!DD'$G2++=3&?2('G#3"><<G25>AD'%4.';,>0390&B%/>G:'?HE5DFHA938527%1,/-5;"1//$C=:C:CFED>C&4D)A$&<&H=2=6G6#$%BEFH3:%#<&8).DF
@r2182
CGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCA
+
+.!2H7G/55,(&H167*F3?%C<>?)"5&1@(4!G9:CG#B'<+A*@0%"#FD+@/?
@r2183
AGTGGAGAGCGCGTTNAGATAGAGCCACTGATNAGGNGAACCACCAAAGACGATGTNATGNATATGCATTTCAACGGCCGAACAACGGTGAAGGTAGATGCCAAGCTACCTGTATTTGGCGANATATTAAAGGTCTTANGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAANGGTTGCCAAGGATATTATNTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTTACA
+
::-F=0E3=!2=$+1:331!H?=G;@;);F86:>8E$A.!#7:8&#AGH1!.;69;*D&6G?F)+"7%.+<.<C*GGFB-B3BF&5*GHA>/;<14#D6,4#C*(G?@5<1.E=104,@BC6=)27/C7'=/C,A,:'FB>HG%7D$)895.'?4>$890A4+#6+,6G<-5(*(D=?=>%9'2!-62,5H+H6<A")%E<(9GB76E($;4B3!)'1<)<9@1;#6"2.-!'=&;<9=<F2,GG:1*G>1.H%7G')#2C'H:#.@7:&G'98F(<;!67:&,A:FA,=-C/(#D:5%'!F1-?D
@r2184
CTGCGTGATGATGTTGCCNCTGGTCGTNGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGNAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCAT
+
+B>-0=,0?"%B3!1?3A42*3)A2+"?D(!%&8H7C(;78$@#!;4B>DA&1HF:<2&()3CD?<;29H*4=/F7-$"3<A'D/4/&,1"FE<&5?<0=:.+0E8@E!(G0-A*&*56!0H<%F4""5A2".C/26.>,'(@,-4H)A&=4G2E)G66?9F%6%C$3D&.&6B6GHE(@=%&#%"130E,(ED&;=4.*D.C.G@4*,4),&3-(@<5E=EA=H&/?"
@r2185
CGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACAC
+
92@..B/()13?,"03-/C@'//697@<$E055D7C9'H!
@r2186
TNCTGNANAAANGGGAGGNAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCNCGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGC
+
""$!$"(!(#'%!)*'"$!**&+"!#'*"+)'%(*)+(%!'%))#!"'(*&(+$$!)!!)"+'"$+'%!*+&#$"')##)&))'%+"&&&&'("*'*)+
@r2187
CCGCTGTCNGCAGTAACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACNATTCACCGTGCCACTCTGTTNGCCGTCAAAGTGCGCCCCGTTAT
+
1;E?(C@37',3A7=>*7+(45+,)".(5AG958=">,?0FE:2@F4!2!%B1&&"803$>F/#;*D:B-B<B@*6#1D1F;H8+1H&B>)?%+=/A//*
@r2188
CTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTG
+
1A)7@$>&',7(2+*DB=/E9@0863&$H:-8$+<7&?+""$2;>:B&,);<:9=H37+7"'2%,E?%(*1
@r2189
TGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGANGGATTTTATTC
+
-C(2?@-?17)$%'/>B&7B:'>E.A-75$3(@@3/="C$>?+.7(+F5<).E
@r2190
CGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATNTACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAA
+
C+?40G$>F*;%!A-0>(-H&#?4C,*27#4$D>>0;.4?,E*@;7BF!:-21;3$4+3E!$D)F'#E'8F$E;,'!=;H,.5G9D%EFBD.:3,@>#<.8!/&<:'?@=$:"G$!'$48$0)4C0
@r2191
GATATCGCTCATCACCGGATANATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGC
+
?%)F!$1'1<@E.3,>>C:1*,2.:5/.8=/(53.0/96DE3<:F$D@6(/.:(>%/D-=!G,-@846.!8+,(+/#/#)%D)21<%H"*#60+?;1(C6%8F&?61.(8&A(9:3.)!*'
@r2192
CCAATCACCACAACCTGACCNCCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCC
+
<&'DF%4=<HB+1@HF%*G(G!),,G0@H&*03),,+?@9:=?/D,)ED<7@55%3!9?/B*3H/A1:D$*
@r2193
CGCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGNACTCCGGCACGA
+
2B=B85+?-6CC@,+--8%==3(6.G,=7E9+C*<6F<GFA(=H5.@.'.D;DBD)!GE+<,;$22?%4D4HE<G'@)E"7;65518D0<#H?*:"",1,"
@r2194
NATAGCACCATTTCTATGTGTTACCCTGATGTTGNAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTAACTGA
+
(6</)H'3B+(9G@<93DC()=F,/G>GA99'0)$F4'4?;'!4+FH6E92#:0HB+.&(9%>B72@C@0F;(GGC!<%C8/BHA"0+.60F$,E!A19D8)3-$'6A?!5'F/A<(<@.)H(G3/D3C6D"FGH&0&D'?@9$
@r2195
TTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATC
+
3,.BD43CC6"183$@"H:E9$#B:AC>&2'#3=B*"FE/?):H*%@6/H
@r2196
CNGGCAACTAATTCAGTCCAGTAAANATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAANAAGTTTTGTTCAACACACCAAG
+
$*+&"())""$!""#+!"$+"+&*"('$&)"%(%%)*&)&(('+!%+$+*"!&")#*$$$!+$)&*##+"'+!(&)%"!%)+))"+$*"#%%
@r2197
AACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACAGGGTACATCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAA
+
.A(6<CF&<+3&>H+@,>D(!BDC8$G5#0"($765?#BFA-!FD4.%-F?7B'54G(<6$F.68-@AB94,H2C6%;0,,E10.*:&>):'B!H"1@AD=0#*2@;9E6(2E!2+04<$"/+3CD>GE$!?7.4<1CH
@r2198
NNGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTNGGGGGTG
+
!+!"+"$)#"&*&($&!'#+!)+(!))!!#(+#''&$'*#)'#!$!&"%%+$%(!%**"(((#***$'*%+!%('#'+$"*+$&#+
@r2199
ATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGA
+
8AHH%"E%9CE$=;-,%/?:&H!B$/?7+:/A&DH)+>,5B2("1C,9=44C:E,D93.&$(&6$+#%<+C#.3GCCF>+BDB!"$=/D#4='&.D).'"#-$?C&/A$::660$;+>H9'%/H@
@r2200
GCATNANTNNTTGTNCCAGCANAANTACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAG
+
$))#%'')"$"!%)&$''"!*"!)!)+$'!&)+)+'&%#++&(%*"(#$"#&)%#(($!)(&'$%)**$**'")&+""%"'!%'%+)"(()!"'+!$!)()#"+&)
@r2201
GTAACCATGATTGCAATCCTGATTGCTGCCTTGACTTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAANATTAGAGAGTATGGGTATATGACATCGGTAGTTATTG
+
$!@6=G<383)'*&B.>;'=FA.<;"41A%"/+"23@!"-B:C&.#&:?:#F*8E1;(H$/-=>B6D(7=0>)A3B+$B+%?6.%2=FDG(!!F6(@C%(B<'9+.3<(
@r2202
CTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTTTTTTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTC
+
GB9,97@@?&"4?03ACE185&>.HH/-'H9>D"9"935-GH2&9;+E8$19/??/-&#&@#E26D7<81.8CGC9G<!".-/-59,.';H$D4H*5953!=CA4")!9A/+>F3/!@:9*DF3%)C621!,(7B).6.,<=+7*B=C@<<GG?25$;%3#&8).(G=B#@2'7;-"G0HH/.-F-?%++<'&)$B-E#/!$A2F'=50':CD0-5C"F-0G02$CB,'8B+;9G#H;6>
@r2203
NCGGCGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGCTGCGGACGCACAGCGCGAAGGCATTAACGCCTTACAAATAAACAATCC
+
!"(#((+!!&&%#'*##$#+!(')#')#%'!%#&(%#$+'%&)()%")#")$*#+!%#(++*'#%%')%*'#!#++)&*)%$)+%()*$(!+%&*&$'
@r2204
AGTAAGCGCCGCCTCTTTTCATCTCACTAGCACAACGAGCGAA
+
(2:,DE.@D)8A&*>)-:(>>)1'$@"-%FF@><H:1E:14?F
@r2205
TTTCTTCGCGTCTGCCGTACTCTGTGNCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCC
+
H4%@09;AB>5;C?.H?""5DD@7B;A!">.4E!5GB)F.:@:6!$?262AB64>#E?H+.*3#)&#@**<6/!"D6*F&!9D6&@,-
@r2206
GACGAAAACCAGAGAATGCCAGCACGGGTCCAGATCCNGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCNGGCGGATGACGCAGGCATTATGCTCGNAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACCTGAAAACGCATAAAATGCGGGGATTCACTGGCTG
+
/;84)04F'&64G'66"!24/@0+#4A:G$H&<&;!H.8:/3F79("45?6=D+7/<-"&1"-?;;.GHHF93(<'F'9,%!;&%7?7<<8*-@44&%?D@(AHG;(@-;9(!F3%")H!56(F*,C4$"*=2&+89:3CA#24&214HH*+#1@+E(F/3HB<20DH(1%?=8>4;'.##8)6!3DD;"B:;A=5'3%'B9-&3(B8.,'8C>H%92,.<%+5--:0;&?:(B"'G#AC+%"B&;B+A?%3CA4)
@r2207
CTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCNTT
+
5,H4>=&6-7,*8FC3,C8/D;(!*/E@&'%=<31-A'+E>)/C*C+-.3<.?$:)$:8A3GC"%/<'?C
@r2208
ACCCGCCTCTTTCAATAACACTAAACTCNAACATATAGTAAC
+
$;8,@!#7$<1E*9$G?/<28E=>8;BA0GCH?#B7<D5=2:
@r2209
NGAGCGCGGATTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGNCGTCAGGTACCCGNACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCG
+
+)=9<7;@/0,8"-'/399;./AG&C<(2:(;:=)<)H&A>:DA);88@@!/@@4$3D!(/&#,9**#6.64."FH2@4E?7EH1(=B./8$BEA>*D467%H/66BD<G?>
@r2210
TGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCNTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCA
+
+*'*'$))*(++&(&"#!)!'*+'$'%+&$"'%!'""&+)(*'''(&###$(!#*)!#+&*'#'*#%"*++(&'*+&)++'))&&+)(%*#')$$%$!+&$'*&)"'&"&"*()%+"+
@r2211
GCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGNTGAAGGGCGTGA
+
%H#@9=)B!&'F*:F26=9F:&$/2>=4(*%F:+"FH(:/#+,*G=4-A)7+<;A<1F+@,,'=C.71?&&-A@29
@r2212
ATGCATATGGTGATGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTA
+
0H9=2'6?F>!,E<B>6>"E=-C48$HA-%<3@8>.A=EA7#F%"<&96G#?1:1:)?B#9!2&.5:+H@C4?0&
@r2213
CTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTAC
+
27=+BE6!7%59%>+A&-'.)CH!H/&1:3?AE*:"./3B>,F1,*#
@r2214
TGCAAACAAGCGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAG
+
7"=!F%*8C10H6@(15>#:F.)17.;>5&%&GH57;E#E@&+-D2;!?,;)GGA5?%5;0"C8"81',>)!F#3!(87C:%)-:F9F";6/"7@=7A:>@@,/%4/@&H;(,/,D.4&A=+.#
@r2215
CGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGGTCCGG
+
B%4<FFEF32.,@>!23:B*%4E+-(9-31";;!F<:>A09/!2"C##9:0&7'C@3#7=?99A:4(>0>E)B$-?@C.#$!G;")9>"3G"$H9=<G'&@-:"A2>?;"+'+39A&(,7,9/@@::
@r2216
GTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTC
+
=#3'"."4B*913G);2B*75BAD+11>!%F89'>GB02H/E445=>@DF7+;1
@r2217
CTTTAATGGGGATCACCTGGAACAGACCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATNCCGCCAGT
+
'3$5<(>-)3**@>AA8.C%#G%'7>G'</!.,4F?A4399>.+D28)'C26*)D$&G,504F:>/&7&)CG'G)0
@r2218
NAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATAAGCACCGATAACAACCGGNTGNTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCGGTTTTCGATAAATAAGCAATACCCTGTATGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGA
+
$+'')!")$!*)''$'*%*)$#($%!!"%(**+(%!&#'$!#&!((*'+#()(&)$#&&%"!+%#$'"+"&*"+)")"'+$%'(%)+'$'&!(%)+)%'('(')''!)#!""+&%!)&(&%'#&"'&%%*"("#$*$&##+$''$!!+'"&")#%#&$#!$)&$*&&&+($$!(!$#%"&"+%#$+(%&$#)"+$%%%%++!#$$#%&"$#(!!()'*#'"!)*$%&'!#()%"!#(&("+"$$!
@r2219
CAAATTACGGNTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCTCACCCTGCTTGCTGAGGTNTGCACCGGTGTGGCTCCGGAAGTTAAC
+
2<D.+!1-)4C"B#>'/HEB1/&G/1F5%>94)8<%:@.342F/'32>2&AE5F'E+2&%:;E$>@."/7)+@,>:=?1.6G=E6<F?+8*2'+H-C&"$7#->F66"?)HC)6B&"!3(-G"(BA>60G3D,G&'7'7<>GC*(/(:
@r2220
GNNGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCN
+
%!)++&*)((%!"%&(&'++%+$#+%"$*))$*'%*"*))+%('#*#)%'($!#"$+!()!#"%**'!(%%++"&&'
@r2221
GNCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCT
+
55&6?C9$?00->C,0)7'13-!E?.$0=92-9+;"%#"B,4-<,6<'?B59='66H!=9<;<@.@7GA$:<8H*.-@E3'G96F5@6E;.=2(D"+3@/
@r2222
ATGGCGCTGTACGTTTCGCCGATTATTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCC
+
AA@8;G89.-0##&"=3)(A!A.;@9F-C441"?=A=:HGE@=.)#!(5E+@;%(8"0#<6(25E57B2$#8%8D6::B:8;(C59,F@4@F(@'#8@.FB+9;&#B(7)'9")9-*/7E%
@r2223
TCNNANNNNNGNTNNGGCATATGCCGTANTTNNCNNTCGTGATATCGGACGTTTGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCANCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACNGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGG
+
$#""(!#'!%%%#"$*()*'(("#"*!)&)&$('#"(%*'#*+'+(+$##$*'!')(&+))!(##$"*'%*(*%&'")"')")+%()!%)*%&"*+"(%+%"$"!!'+*&'$!()("$*"(*#*")+**"$&"'#(*)!!%&#*(")*)'(*!%"&#&)&("*((!#"#'')'(!)$$"(!$))&+%&&&)()+!$
@r2224
ATTCAAGTGGACGATGATAAATNCACTAAATTGTTTTATGACAATATCCAGAAATATCAGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACNATC
+
1:B2GC2B*#5B/13$2($&7,;&!21-,&>>>B@5'B:2A4$'4H,.;"G5'2<B':F?3#??.;2&(=41&-HA'%1"9C'-!@EC<!1E4;D,#07B?'
@r2225
AGTGAAACGTATCCTCCCCGNTCATCACTGTGCTGCTCTTTTTCGACGCGNCGAACCCCAGGGAAGCCATCACCCCCACANTGTCCGTCAGCTCATAACGGTACTNCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAANGGCAATAC
+
&C80-)6*84!+9!<)4#CA7"E#'/%7+307!F1A3!D#+*;-2F>,:;)A7",G*45%./'D?%.+80@(9;);?*)>"E;1:8F*HE07;D5?@4("$.-=/+*@E1&#><D+=C)A:5/7<6,'2&.4(?/1F*"/$<5=1+9!<E*A@==A6'>D)/@??5*E.+035+;29>8/4HA>49DG<:42B6:)3,GB$$64=F%1+&1?(%E4GE4:0*!<3=B<%E#"*EB2-&6A+D4>$6-C1(("D@2(@F'@/"'4@=3?,.C"3
@r2226
NCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCG
+
%8/'*E?20$3<AG%?7H4E!H<B4@?HA$!A7*,$G#*(F=<*5E%D@=@869E
@r2227
GCTTCGGCTTGACATATCCCGGCGTAAATNCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACNATCGGCGAAACGTACAGCGCCATGTTTACCAG
+
(=.A<5='#=3-1B84&552F%1);CH-D=-9)ED5;(<%"$*767F;9A8C#(;?90;72E9#?A>F7>10D&5"?'>$&0C1"-E),0*<C.;&HC!;&:=,D8
@r2228
GCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTANGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGNTGAGGNCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGNAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCG
+
-*A2.3=;2=2=56=>H07(BH#@(738>)F"#45@@;<1.*H$,.9.9+-//4"@3#7,A,D(AD7=CFHH)@>B1D&G'4&!&;3,-1+/E@GH'4#<9.:((G)0@;&,D="%$A1D-#253D??0!-4+-"::AE:3*):CB>(1';'9.3-=33E6H;(.0:CEHCH5D;7-=33H)9#8;&84?0?+-;72,:!1/*E/2E'7:H74G*2>>1,FF$C<<@+=*A,"8$004#(2$:.3&@,=D>?+EB@B;(5"3:'*7?#?&!G.F30118#9/.:4%E1'2'1:&5F36="4E1$A%975?7=3?GD0>(F<*=?7,(0F%H3E,4BD>;#9;GCC6>B&93*&6
@r2229
AGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGT
+
B0A->EE/C+6+A,;3:@/7"-F+.874?8+"@FECA@A:5:&D'+EC161;/(E-!:-D79;;?H"0AF>722F=$823+9?
@r2230
CCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCNGAACCAGACTCTTGTCATTTGTT
+
03>/GEDH-G&&8$92+!?2/+)6?4*5F(!5E00:-=/,9ECA8*6#*:!)!CF?@0@.$'7B+4)%4-)@#D;C2HF<+=@66&D*1BF>803B?3,+&9F83!3**9?1&'5G)%,,
@r2231
CNATATNTNTCCCTANNANCGNGANACNNTCTCAATNCGTNCGANGNTCNGGTACTGTGGGTTTAGTCGTTGNAAAAACACCTGACCGCTATCCCTGATCAGTATCTCGAAGGTAAACTCATCACCCCCAAGT
+
$%&)(!"(#&%!*!*!$&!'$!#!(%*&")#(&'#&!(%))!)*&#')'(+%*(*$%#%'+!"$+$"'&$*!*$'%+!"%&!##)#)%$'(&"'!)%+#'&&$&$#(+!*(%!"&&*+)#))%%+++%+#""+
@r2232
GANANCACACGNTNGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGG
+
$(!)'$*#'&(*%""()+%&"&&&($$"&"(!%)'+"%#+)('')$&%%
@r2233
GGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCCNGAACGTGACCGACGTAACCACCGCGACATGTNTGTGCTGNTCCGCTGGGCATGCCAGGACAACTTNTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAATGGACCCAACTCGAAATC
+
D'+;21EH8;(#,C1?7611>E@6.=%(*+/,#C+7.A/+)/<@$B=$,)C"4#".E&$HB?$5),8H0.)''#@G@.C3!,6+1>F<F2(0%!=)F.*A+8B,C=D;D)&<$-!7@B"AAD&'+7CED)0=E&/3H.GE25-HC,=%D6%-(4"/DC7.+/0@?(E4:H-19-@7-9?.@>?D<;'61GD.5&1E',B
@r2234
ATGCTTGCCAGTCGTAATCAATGATGTATTTTATGATGTTTGACA
+
9;!CB@"=F&"<C#/5?%)E;+>0:??442@5&83D:;E6:AAA.
@r2235
GGNCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTC
+
-D2!'!*7);H=34A((C$B@F/<CG&B!5H6+54+($>GEAG;20)D/3F75B?6"D!0;<28+-0=;*(,=A"?"6
@r2236
CGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTA
+
C7B,0,G?,36A3#4*(+$&;/!"'%7)DC;3.';**?@2(2&2$4@
@r2237
NACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCNTTTTGCCATACCACGNGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGG
+
!=.2D*G:5@+?(7@.&)-E-<(1G1=12B8*?%F@>/!>=&)F+$(H>5/G9"%C#GF39!):419#2836</B!9'<:?$$"GH%'#$D3!%'8+<>>,;6+9/792B&9B!H":42A%/08;21>:2*B0%GEB59'E&EF@1E<32;1!6<%
@r2238
TGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGC
+
4;BB=F%-<@6'&+@,B4+?C4/@;+@(E::6).=(5D%2
@r2239
CGTTTGATAAGCGAACCAATCGAGTCAGTANCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGA
+
D-*D3BBE<5*&*9+>.=;1'"D3B)=/9F*389?9/130EG-;C8853;8"0:+=@(+?#+?,H/./1
@r2240
TGNAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCAC
+
=/"-=H26;5#'.G!*7GA2-CGF,;B-7<&,$G$:3.9%6+F<:16H,>1'/.",B4<'.<F=F
@r2241
TGNNNATNAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTT
+
&&#!&$"#!$+)(('$%$**%*('$%%'$('""$$%&")()$##()&$**('%*&%$*")#!(+%!"(++%$*%!!%("'*)*""+&##+"!")((""&#%*#&&!*('
@r2242
GTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCNCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGACCGGCAGCGATATACCGCAGCAGTG
+
4('DD4DA="!.81?+:@$@B,':3=(;"C'#9'<2471$)!./3"54FACBGC=*H%.+2A$"0GD*!)$8ED?#>?9&5#.+!+2FE633C:D5->>B?+8?-DG/7:8EH#)8&5'&'<:3<E%B<;<G?=63<-B!2&%8!.<.-<&'5=7$B:>=E@/(*G&?,7+!06H9<CH3?(>(G?A/<1:)29*$19$EGBH(H120=432C%3;B&8665@!,!GB3+E;$0.E.E%?C;+0:6F214..E).@*8>+9=7E<-#CBH3(A1164"&*H>G7*)(=C4)7@56;BG>"=1?#4/?<9D;H3??-(.=(DA5)H6/%4F8:8B/<=)&0@=,)=##*:(>@;(@>-!.13@E0=>@4+*1B?:08%&6.)%?/=)@7HC@*;D6:'G$A6EC.@#>4HB%&1'5&8B%><'9#A2
@r2243
GGCTTTNTTGGTNNATNTATCNAAATGACTCCTGTTGATAGAT
+
%$%!"($(*#!&$")('%#&&!+'+&%!"##+(*+!))%(#!#
@r2244
ACGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTT
+
'"H1B'D%0">=F90?"-8.18=(+7-;;H&6945;#960"49"=*<2F
@r2245
TTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATNGACCGGCAGATTATTATGGG
+
3E5,C+!3F.-'2=*$:&),939$/..F?#"8<%44F@=D<-.H;?A#G4D+-#1">&#4<?03&:"=-HG1(E*+1G95#)+("D4+&7+.>>-0B"8/DH(D,@&7-A+1:&/==.H'5C%<9G?%"-/4B-(,H6)D(AG1.=/88-'6F</)D0C.F/A:+?!=1>,AG':71;/<BGF7
@r2246
GTTTCTTAATCANCATAACCTGCTCATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCC
+
:D5,1>!E8",*#&B%A$=HG4AE+E&3/#3A6."8),D-@=F(:GA@<39G?"--&$$AF4.+;1
@r2247
AATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAAT
+
))8/A<=>"C<H-(%03'G<:E!A=*8#=,6:5A'2>%1'6"(02+3$%!!3A*08!!4.@"947D"*6H9"#(@>3(B<AD$CG11#E?3!GB;=6/8B('!.-%@&D0D331$$48DG;
@r2248
CACGTTCANCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTCTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTT
+
G%+(4835?!)FE:.%#%)B>F=C4-'/31%A4>@#;2H&C)"<8B6;4$).)"&BC*8)F@E:1%$';>=*<HE0;FD:2A8(&D1,=,:-0"7G4@FE09D5BA*(&E&#$C/9@(.#;01B!-)B=.F480+.(7<$(,0GF1G(*%!?"6&<:(!4$C#C!F?HF-,783"*(-7#6*
@r2249
GTCAGNCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAAC
+
A)1(:D.##C0B29DH=2"'6H1?:G.H?'=/#F'5(!$+.93E#3<%"0*A2F;1?/#%;;<%B
@r2250
AACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGG
+
HC7BD%?//.,8)F:;*0F=-96G(@6823)4%&;:+(E(6H
@r2251
GGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGNGTCTGGTTCAGAAGATAAATCGCTCT
+
BD#7/8435"?4904>AG#B'?FF6>&?F4;2740(+'*>H6!H"H'#0.H;)'#(5B<$!.B
@r2252
GACGTTTTTGCCGCCCTGGCAGATTTTTCTGCCGCCGTTGCCGAGGAAGNTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATNTTGCTGCCTCTTTTGAGGCCACCGAATCTCGTGCTGAAGTGGCGGCCT
+
?%(2/!EDA6:C!;>DB)5')5?">#H*5>C?H>/+,,H:77FB<*,31$?4D!-&65$$#C?GG;C2E%A9F62@F$75220AB9&,:6(H?)F-?H+1+/</E=BGH:(;EA"@%7;64'+@>,>+,-H>088/?"C
@r2253
TCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGANCTATATTTTTTGTCTGTCCTATAT
+
C?;"'6H)26":4C48-!*$DHA%*$A,3),=>,-"7<"-D=<!GB"30;%;F*'D13=B-&FA/:&A;D$$/A;@54.!&D2*<H?!9!0<FD0@*979$*+@/?B:3?
@r2254
GATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCG
+
C,,)=%.)G2F,HD60#C@,:@'(.?-D$#6+DBH#G">'
@r2255
CATTATATCTGCCGCGAAGGTACGCCATTGCNAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCTAACAGGTCATGTTTTTCTGGC
+
:1$*$,HCEE<8;"FB3&/="#"<@#HB'CH/5!,@(.8DEB1@EH?5&F9F%2'$6C)B(7()*&H":<(<7=9*C>3764?,.$56;?>2B9$#82"@"@:-
@r2256
GTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATGTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCNAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGC
+
A/#,)-:G:;G6.)4-7!B;."10-*##"7('/3EBA3$+8DA1>/<75/GF'@.E5!DA5HB..*C$3&8.#4G$,*D-A#$7>7.-.!E;84"400:99<A::E7?!5<A<">22&E"9?B,F+C'D'G3:3=$$".",?FE+.'<(1"F689:185>81($=/?:<(>@5/?-GA;G)6@=(?E:!;.?&3.
@r2257
CTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCANATCCACCTCAACCGGATCGAAGGCTT
+
%+*&)**&++!$&+&')%")!%+%!*)$#$##(+%*'#&+')%#&"+&&+''"%*#)+'&&&((*(+(#%(%"')+*&(!#!)
@r2258
CGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTNGTAAACATGGCGCTGTACGTTTCGCC
+
>?41C#D/A&?'/14==-'<4E+66<9='9(1;;-">A34F63/>!(&DCG52,4"E=%2/=*1,04/=-1<D,E#0@$%8?.$1@43+;+=%#=1E6,$1*#H/5
@r2259
TAGAATNTTNATACNTANTNAATNATANCAATAATATTAAAAATTTCCTG
+
*!")'*')!**&)%'&(*%'&&%!*(%(!+#")!')**$$"&)%+)'+%%
@r2260
GCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGNCCA
+
A=76/?D($3>D9"HA<11<(+>3B'/AC:44.H&<7.<+')?-<,F75;%8F>AF,2?)=&,>F'1;??>)F$*G<7!D5&!++!0'BH*/,7)#B,7GG?&2=5<1%*H-%+$'<9)47
@r2261
AGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGC
+
="+=<#=?*4(")'4C#D@,$FCD.<7)AH".65A.'>C'/,*H&B9&->/-<-92=<@G;:=%+HD696
@r2262
GCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAA
+
H813B"+3,%#DC86@BH?='CCBG*F7696+9"8E=;,!)H9G)"()?@+())A'
@r2263
CGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGA
+
.@2&C:5A'%::5#+@.HC(31HH""-<?CE#%=<++9*5F
@r2264
NGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGNGGCCAAACGGCNTCTCANTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATNCGGGCAGGCAACATTAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCNATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAA
+
'EA8*6+0=H$2,*C>4-95=."(2#9BH5'52+!-E)/9E=+C5FG#"(G":D#21=/#*B/'&(B%F.#15;.>F/1!,)*15&4%72F$#:?7*5!7/+6/78DF4@3&H/9(5<15(EG-0$9E61AF)HC()F=18EF=?7)45"?A@A37!/5(5&%=F8>'6"B'75/9;:7>($-@?%=B6'7A"1=:B#0HCA=2G$H8='!!E(.E:;?-F#E"*C;6$9+6=!=!<?*B8?$4?&ED9E2?@=>0F,!4/3$E'#-@$(GA6,C/18(2,'#;E>2&2D<96%83!,!1A6+'73&D)8.6>E63ED6C?-56B"2'"E&/8<!'4,@$E1*(H5/3!3=@.A5/A!)D1+;EA.D$;
@r2265
NGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGACAACCTG
+
#H;952;H=9-(#..&<E-.*?3!(5F<'G+%)<)FEH)-4;)H)*?6-*
@r2266
CNNNANCTTACTGAGCGTCCCGGNGTTCGCATTCACACTGCCACTGATATCCGCANTTTTAGNGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGNTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATG
+
%%"$#"+%+*&+)(*$(+*)"'"%(&(*(%($+'+'(!$!!*)"#*+%++##*('"*+()'""$$!!*)$#(%)%&+"("'('&*#*'+'$+%**)*+!#+%*('!"#!+#!)#*+%("!'%'#!#!%*)#&%'+!"**+!#(")%'$*'*!'*&!!)"*
@r2267
GCATAATCTTTCAGGGTTATGCGTTGTTCCATACAANCTCCTTA
+
8F*1(C79'A>:@>D2()02G2<2.#E$8>05CH<'>>%+!F(7
@r2268
TACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTNTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGC
+
,0H/>8.',@8,*8&G">;+"#;#;.7=#A54.#%/6G8,54/E&0/6>;"#,5,,9A#-6?@2#"G=H@G4-.1-A-5A#3*GHG6*6F":#=)$9:08=-=@>2*18-$F=*8;.=6:$,'E+"!A2"'9<(><G&+?.9
@r2269
GTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGC
+
,')-"7(:(/D5AE258#7D229-H-2@"!+$0@,B9>8=E)3%AGE,>#HG/8
@r2270
ACTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGA
+
$%;'<$?%1E3%&%A%=$8&<C1(C";C+4:@@#>6'31(H7E?;(675.2)<3'/)7"9
@r2271
NTTCTGTAAGGTTTTGAATTACTGNTCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTA
+
!59.;'&'-9<D)9:.(-D;93;,E2,!#+BC(<H3H0F,H/<C*C%!CB&0=$?@#./G*9'
@r2272
AGCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCT
+
&"C-AE*#B)-(*F;.%-93H:%)E#0E2.B097(,!@BF
@r2273
NNTTGGTTNTATGGGAGTAGATAGAAAAAGACAACTCTGCTT
+
#"*'(()(#&$)'!+*+*!)+"$$'%*$''!!')"&$()""$
@r2274
ACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGNAAGGTTTTGAATTACTGATCG
+
+%!&+*"+(+*%!)!%"*+*#+))%)%**"($""&+!)'((+("')'$(##('+*!"$%!(&"%$"'"&$%++
@r2275
GCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTANATAAGCGAGATTGCTACTTAGTCCGG
+
&8E2=='DH,>0<80'F,#6A6,.#0-?"@#9D1@9+G'"F#3-97,A2+A*-!.!)->&C7!H'26?:+%A=&1DH$+//)3:5C/H;,E
@r2276
CAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTC
+
G$#13.A'(E6C>9"7@2/98'((#08F(@1?##;$7%F?5G;$/9A:28DG-4)-!G'-(3@=7=)C6;@)#CF!.$3(+42.B.2D7/5,)**6<*#A7EFH@+AC"C9/>7
@r2277
AGTGAGGNCTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTNTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATCCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGG
+
(%*&""''!+"$"&"!$"$'++*+'+&&*)**)#%'#)%+)%'('"$+"#*$!)*%%$$(*)%$+!"#$")%*!#$"+""!)"+'$'$($%"+$(&**"*()(&'%%*!%*'"*'*&$+!+))!!&!(''+#!)(+)$#&+(!$$$#)+#*'*()!)$#+$'"%($#%))'!'$$%&'+$$+%)($!&'$%%(+)+%&$"$(&+%'"+))(#(&#$(()&!"&*&%'!%)''++*"&''#&%)&'#'+'&'$%"**"$#'%%!&
@r2278
CGCCGCTAGCGGTGCAGCACCTGACCGCACAAGTCACTGCAGACAGCGG
+
2@3:D?9#>3A2%':@+)5G2!:.19@.B"C9$?$399'C%9>A91>/-
@r2279
TAAAANCATCGCTTAATTTGCTGAGNTTAACATAGTAGTCAATT
+
*%*')#+)++&'#!'%"(&%)*#"')!#!##%)*$"'"**+!&&
@r2280
TGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCAACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAA
+
11C89?:A@%B/:A@8$C'$,7C6/1?,>)3C1A4C":G5.D,EC6<B>4:!5B##3,9'+",%*F'15)<.AG.0-G(4AH>9E3(G")7$=@=&"7H'8"@(&<;;7?!(=(9G.B;D&;)%B!D5(3G@96;1'(>6$'/739:;?G!=.0<
@r2281
GCCGGGATATCGCTCATCACCGGNTAAATCCGGGACTCCATCCACGCATNCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGT
+
5%@4989#;&A1#*--2E?;>F@=9&B#+7+??)4>HFE1B+<$-7*F<+*?#>2!60%"*"7G"G6,,1,E%G2>3-H&)E*,>>E7!5B"C*<')+<DF'*9&%,E5>7E&),<:6='"
@r2282
CGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTG
+
&1DA@B287684.9+F4&F%=(81/=$GBEGD.%*33D,(7-E/"8>FG
@r2283
CGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGNCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGNACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCNGCNAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGNACTGATAACGGACGT
+
18-,@-/#,/9;)31.*82H)3?4294+5*-956$9C"2"6!/79F!#*C6+0,1FD:"@C>1F*A#E5F;:3!F$"D+H#E26><CFA?;5&+,!%B(F=2=;5E45"0">/:<A**E2-#DH63.=F";G%:;/;H(%30$%,E@G>BD>5%<A6D=4&"156;0@/HB4ADB'G'@DE113!E0'>F/5$5B%4?:20)742498.:A%?H+!7:9"9?D4$H.=F5$:@&;A0*9HCB0+*80GHD!,5?+7+*00A,(&2.DC%(&6/"6":,%%#=*:(C)>&=#?-3
@r2284
NNNNGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGG
+
!&!*+%*+$&"'&&'&*')!"+()("&*!!(#+(#%(!+&!&)%#)%%'$(""&%$%"*%'$!'!!$'''*'*$*%+#"%')'+("'&'&
@r2285
GGGATTGGCTTGGGTTTATTTCTGGTGCNTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTNTCTCGCCACACGTC
+
)DB04F)3@46@B%!F$.G$E(9D-2'&?+7A8B7A:9)/4<(67B=63!"A2";F+,3>@B56&$'E!'6E>;"F!05E4(0F-?=4+?9>?BE=(C9G
@r2286
NNCNNNNTGNCNNNNNCNNGANNNNTGCAGGCAGNNNAATANNTNTNNNNNNNNATTACNNAGNGNGANNANGA
+
!"###"!"#$$"!!!$!!#$"$!""""$$$#!!!#!""#!!$!$"$#"!$"#!!"""##$"$!$"!#$#$#"$$
@r2287
TAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTCCCAAGTTCTCTGGCAATCA
+
G/66$2@*@D80<'?$EF40H<6;*7/8:9&?+!C*H7)9/69>,952@663.)#G
@r2288
ANGGCTACANTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACANCGCCACCAGA
+
*"*))((&$!%'$+)%(((*$)%""((%&!#!&*#""+*(+$#%+&&+'!*#"$&&###)#)**)'$*+
@r2289
GGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACNTGATCGAATATTTCTTTAAAAATGG
+
2";-.4<+D83+?4F>#'9-C4A:#'8B=0'94%4%)8E=&&:1+)!#6%7,@8#*2?5157'(4?B<524@,;>A@>B-8.'(=%.9-<6!A>0.?,0BA%409.=$.D<#B49;0&/)78D4(+"3F#;2:=@)
@r2290
TGTGAAACACCACGGTATTTCCCCNATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGT
+
*&*&)%+"*(#%*!)!!)'+*%%$%!#$#%($#())*"&#$$()$&"$"&*$("%#$!%!"+)*%%&*')"&%*($!!)!%$!+*)'
@r2291
TTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGGCTCC
+
9$8@*(/B=6)-.7=H:;2E<<$>%+H*98=F8'8@*$6(EAD,$1;E"%</
@r2292
AAGCCGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATNGGCATCAGAGCTGATGAACCGAAGC
+
#!6>2=#BAA92$AHC)4@D.H.7FH31@$B(9G9<HD+:8)1.(.$.@1;4#=$75?C)E"60+'7F0H<
@r2293
NGCGTGGCCTCCTCANGGGGGACAGAAAGCGTCACGCTGTACGTTTT
+
&"+.%6F"&:A-!6(A5.G/EG(8C3A7B31-,,G0<;,0&+0.;!=
@r2294
TCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGCACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGT
+
7H-5$!@7B6H3&"7<$A>3#,#8?;<E?BH+)$;#*6,+B8027<!1+;(E8;6)?.$!6,4FD"!<0'.-:,&@
@r2295
CATCATATTCTAGATCNCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGNTACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCT
+
?E)*F?&.BH$A274+!!8D4(G2=(;)>2+3/76D?!8!B("-6)A+&41C;!'7'H66EG/E'6:3E4;$A<@)?62:2AF2FH+.&;A1<%%HHDE(,&;C1BH2/!/!C"H
@r2296
GGCATTTAAGAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACNGATCGTTTCCAACCAGTACGGCCTTAATCCGTGGACG
+
76/54:7HD6.+<8</290?G)6/AC-:*F!#CD4("+'+/8;+<'!!F@9@.3,F+H).3"=55HE?*+<D>'7B2F):)%D
@r2297
ATNAGTCCACCACCTGNTNAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGT
+
;$#*?6!@:A53A&)9A82C7G<=-3'!')58>*0*C%(ACG4.F3%80>7!,!G>)**,**<-;=(1$;,A34@9H:%
@r2298
TCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATT
+
3&?;87((*%(-#?DA40H%/6?D,:)E>*+246>#-,A.B6(86$D4;0@-$%(#,'6/?=.">G(8,=/9:3/=$(%'6()H
@r2299
ATAGNTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTT
+
*#)'!+$*!$&*&'%)'!""#"+%#%+)++)$(+!!)$&++!+&&*!"*
@r2300
NTTTTGNTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGC
+
%1>)1!C&6+G5+?E@)F!50646CF20+D7#??.;8;(2?@<H7;/D3D2#AB#.807+B(7.-HH-(97D.*2:G?$8G?,B@-6%%E>1
@r2301
GATCCGCGGGTACATGGGAACGTCAGNCACCATNACATCCGGNGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGA
+
FE'A!3EB&9%$B(*';H';(*,6%GB0)%>**+9?3G!==&!7&:E>#D!/A34H0H:<(-#F,"%=:B/*G-)>>@)228()7<2/6(#7,"B;0??)%H2D>8.$(C!B>0/*2;7<4#/1=AC-:CCHH;81!55!@0<<:35B$C0=C/#='#0#?+?&=*-*B:FAB=+/=04/9
@r2302
AGGNGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATANACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAG
+
'>3,<?529D'3)D@G5@(G?'8F%&C(B3)3<&91;331+(-?F86!5<.E"(1?H7;4#3DC6.""9)>%..6.!<'&@32C?;A5,@H,<&:F$=C79CD'D&.EF2&0-#C*A(FE?D).@%<*"?BAH7/@=6"@(
@r2303
NTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGAGGGT
+
"4E81E,'&,/4.@9)<2A>D>'@2.?@&A)G-$;#9%8CC+DDE.*5@7!42F?;##&&+<*7>>E4;AH936D(C@#.$!=5G-*D>+*6,"9,H&@"4<:0?+)<356,'?<E>%G6"6F0?952E/84%29H*C!B),$,:7E8*$%*+
@r2304
CGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGT
+
70(+70#,.9<H)?6FC'=C?#;';;77/+>$D!-:=);BD
@r2305
CTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGNTAACACCTTCGTAATACTCACGCTGTTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGT
+
EB<)!59?!#::/(:31E2=(++?-H8BC7C'"7H(H+B"G<,9*=H*C!':->;5#6H453,>6*4:D'$0D.9'H6$;"*5E3(,#6,?'62#F$G'$F5F.F4*&,*,B%
@r2306
GTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAA
+
<CE,%-A2C&7=4:6#>->-/:&8,7.1%!1=F+4D/G=97=-GF!'CG"6'-2#=4F)?=<@>E=/B*90"<+C"6F+<(24/,;!3C=,(;>#9B?E98B!2;<)'-64(,
@r2307
CTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTT
+
'E-D96">88@--'?0@%0;:&>>1&,D7,%;$47(<-@(.8A@F$643"8"D2?*GDG:A*
@r2308
TTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAAC
+
49*#(%'2E>>H%BG-G#8,E?E&80<30-GF@DE*5$>>'4-'<9A;B47CE3#7.8!6>8FB7'#8,8A-.!0<8$GC6*8<?BH';-&:-?60;>5<6(02-/6E,B3=$H
@r2309
ATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCNGTCCCACAATATTTTTTTCCT
+
=-H)#F!'/1=$)$:=*/7'/6;%.;C!2&,-?@7,"E#@.CF:*6GG1%G$<$.G:8B'3B3A1@"$.H=0'B?E7<)'2)(
@r2310
AGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATACCCAATTGTAT
+
=$2!6,@!5G8D@?C,*8?2&)7/51GF>7@3$>+&<A:B".&GA()0.GC9E5!:.$-0*7A&'!2C%,/
@r2311
NCGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCTTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGATAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACG
+
*%=4?B0;>$802E8+-16AH5A?=4?F'F;3-*+*-*EA.H3H1D2A$+)-)3'CDHC+*6E<7!$9-ACB3BF96;0&7&8-0$<;*90,5C(!-%F80#5-H4?/"D-*0>*5&A"5DC5/-4&##9*&%6%"4B2G'4"%8(4&*6-(!4<+E9*!F#"6C.3.+
@r2312
GTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACNAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTA
+
.."E'&0:<;'*/FB-<AF;"',(F5CE@?-),=ADD'&#B42%C.A0';H,%<B11H8@$@.;($?;=90.3A%?$8/7'+B:$/8)#-446DEB;19;5/06,,4A/.<3"*<'!*-.!)11#?G6D-C89<)$<0+7+&:B&
@r2313
AAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCTTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCNTTACCTATGATTGATCGTGGTGATATCCG
+
16-7D->*:56A!96AH?D-A-&AG"??/69%GG%&',8>@8)$90:!*&(#:'%'-D7(@"3#%C*"5,?@A);$5+*:(2/-CF#*,%1E;EA.E$G)@&;18=A93%'.&?6@>-4=2':EB0!C:;2%B@972>.,6@G;*52=>=:(%AB0E2(B#.'8$4B!&G&
@r2314
GGCCAACGTGCTCAAATCTNCATACAGAAAGATTTGAAGTAATNTTTTAACCGCTAGATGAGGAGCAAGC
+
-/6-B)B%$4+H?*65A>DBB"*=C!!-.=A$)<#C@H$#"E8&-,3E8!5AEH++;""*DC'%>8C3%)
@r2315
CCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGC
+
=#.5+4((D=DHE@#C+!5*,'67!/5=*+-!@61@5>C>8/$=AA0,3&4)5.G7+"C;G0(+E226A!$!@0?84)G>40C.?=7'?8?//)D7D6<=$,&,EA&2&::/;$;9(00
@r2316
CATATGCAGATACTCACCTGCATCCAGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCATTGCTTGATAACAGGAGTCTCCCAGGATGGCGAACAACAAGAAACTGG
+
,$B8:&G#F3G*1+'CC%$;"D<1<5;&;.((61"6<=4$=(<(#355+!2H(110;*A(BE..12'*,G=>0)/6A9(&0-3$H7(2@<6H3A#+'E/>C#1=))EB;F4'26#G$3)!62"6BB%,E(89,*H6(7<'3H;<5D"685$;::$B7%-$C.&=E8''G(E<9-1//&$'2%6
@r2317
GTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCT
+
D<2C?H?07&#03"H+'(<7-&$E1*%H015?8A'?D.77#+.'2$%0%4-C""
@r2318
CTTTTATATTGGACTCAAGAATGCTGCCANCAATAGNTTAAAATCACTAGGCGATCTCCGCTTAGAATTGATTTCAGCATTTAT
+
*:;5(7?D&72BE%7+G-<B>(0H,8G,+>'?;.5B0&E><.8H<=-.#@=9*$1@#F5B;"&507C1D8/+!/#0-GB;H#0*
@r2319
TTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCA
+
B=A".AD/1F'9(91B;(':"5G9?;77!-D1*"B3!:A=F9;))<D5><46;>)E-BA;603!;!'F-"D#D<A75;$'$)&83(#!B82<A@>!;B-+#<>(4/&%#AC/5=F
@r2320
GTNNANNATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCNGTCGGTCGGGCGAG
+
%!&%*$)*'%%'+&%($$%*"+&&"+))*"#)"$%'*'!##&&)()$#()"!#$+')+#&%'"(!)*+)$$")+"*)(!'
@r2321
CAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGNCGACGCGT
+
:E??).,"+&4625,G6BF#$1.C9+AD5==#A6'9>@'2*9F.7)%=%FG"<75<A?,(C6-(#F6$@G<):60'+6598=FC($G4--A2>,'8'C)9B=D>8>$"(FC
@r2322
GCNTNTATNAANTTGANAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATT
+
##()$)#*"&!('+&**'(*"**)%!#'()*($(%%##*%%*&&'*)*'"%'"#+(*"(%("*""!*%)&$"(*'&"+%*!')!%*('))&"('*!($*&#"#&+($+%*'+"&&!()'$#(%#)$")
@r2323
CGAGAAGNCGNGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGNAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTGTCGATATACATTTGG
+
!#)&$&'!$#*+$*$($*(&#'()%!#$+)$&*!'%'#+!+#&*(+#$+)*%$#"!%"+&!&+$+!!")&"(+*")"'&&&&+*##%!*%$%&(!&+%$%*!''!*)'&#"))$&++%(('!!'"'&$+()#$)&"#!))+'$"!*+)#
@r2324
NNTAGNNCAANGTANNGNGCNNNNGNNNGNNNANNNCTCNNNNGNCNNATNNNGN
+
$""$$""$!$"$!"#!"$!$!$!"""#!!"$!#"$!"$!#####!!!#$""!"#!
@r2325
CATNGAGTAANCGTTTTGTGATATGCCGCAGAAACGTNGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGT
+
!D1?55D4-=?H0!5:?049C3A!#519/<%6=#9CE@'"!4@&!!?'A:A'/0)1+;,E1<!9!,4CB7<&%&/
@r2326
CGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGNACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACA
+
G56C:EA%'90(;45+5:.8BC?6"<#5:7D/5#>3933&9$$&(B"+97:BA:$45+:(>>:17;%3,,$'?,(4,F>!?2!40<)0?>-'*%"0HB4E'6B9!%#&2&6?F0*65)2:3
@r2327
GCCTGCCCCTGCATCAGGACGTAGCCACACGGAACGATATCTGATGGCCACGGGAACGGCGCACCTTGTGC
+
,!+9E"1H&56@2?E):>:"B$HBG,D/"(>@G?C!/3=;<CE#5!(.4)"?2*<,=8/D#A+-"6"D&>4
@r2328
AGGCACAATCTTTACTACCGCAATCCACTATTTAANGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAA
+
C-'5$:83A/(1,>((:;41/!H1+-FD+'(!%6)H-/7@#,/0*E06:=#2-(%"@1@.8.*?;:>#2)<*%,B#&4G%1BD3'?1(?&81%=/8:;"-?0A,"$88;,'-,9<0&GD&$*?-7?=,#9:7B<5!HF'!B!8H44<A61A6/3/62
@r2329
CTAATTTTAATACATAATGAATGATAATAATAATATTAGAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAANCATTGGAAAGATCAAACAACTTGTATTACATTGACAGTTAANCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTA
+
-59.*0/H#&E'A+A*605517G88-:5-7+!()1G?$=.BH(G*ED7$&("@@$!G&#<"5;%@C02-#4E7D#"$"C=1:"5;H157.?)?(+B,<>/#"/33/>"(!#EA3F,!+E7&47.H-%65;?D,5(5F!2@8C$3'(1.8/;@.>$&8H):+<AE<2)@-+$"/3($
@r2330
ACGATGATGCGGGCTTGTGGNGTTCAGCCGATCTGACTTATGTCATNACCTATGAAAT
+
2"8!8B"71AGG;8,.:>H.G1*D".09(CC)"E/9#=-E>=4(84F'7)>8G03;F,
@r2331
GTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGNGCGGGGTATCCTTNCTGCTTCCTTTACCCNTTCCTCACGCTCCATAACTGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACC
+
?=.&9:@&">&@%9<?D1C5*$<!<)C-3!6E43<>7B-<13<H-'=H%"D9DB:-D4?=52:>8E2$<#28$3*58D)*;B&??H.*8.10=8FG"+%/>,?F.+,22%%-&BF+$61161A+@6D,#!G:/$B,4H8C)G#''<;*E&<-!G",*/(;)@9=/+/D:58#7D<!-76>&3->2$:#?4;@E%"!D;*A3+>,F$;)780%,*A)$C!<.EF@*D'+2GB;A7'$&75$0!D3=3A2$%9E'A!$($C,D!-$
@r2332
ACGTTGNNGGCGGCNNGCATTTTCCCGTCTTTATCATCAACG
+
#&$))(!")$$$!'!+#%*&$&#!"$&*)%$+*(((*(%!%#
@r2333
ACNATGAAGCGTTTCACTAATGGGCGTGNCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACTGTGAAAAGTCGGTGGATGT
+
)#!*#+*()#$'(%''$")!#(#)+%*)%!%&%)#')*!&'#$($)%+"%%+*)&$"!"!%)(%+&"%(##+$**"&(#+**#'$)
@r2334
GGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTNTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCNCAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAG
+
:"5/,F?B29+EC54160#5#2-:10F14/D*--2D?EE=@-/1,H+67)%53>!=/7?==1DHD+!?0-03>?&6(?)51&0,A8.2F-F%#D46D>G63HA?3("/C06"$H6=5A+A9=BCB@#+"(A!,*%H<':@+8G-*GA7<A&=<*E8D63<4,<-3H8C61F/&=$F&
@r2335
AATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACT
+
>?71%;315#>%F*<-06#'7<D'8$0&7-9*":9?2/$A:,
@r2336
NAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGT
+
!?E6;D#$08?-*;@!>'8F?):(+8C9<G'%&)3B1)B+D#7>
@r2337
TGACCCTGAGCAGGCTGTTGAGCCAGGTGNTTTCTGCATAGCCAGTCTTG
+
A!937EF<"#/!>%@4B/:A%G9>B+G"!%#!/!A%<12(&'(/$F9&80
@r2338
AGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTNCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGC
+
0B:C3DE$$@2-)&=3/+E=,2$G<,4@#@43<'G-5/=<,"*(H.:)DC<#1E+9-5$2?=?!CB?(")G5@:<4#$B)8?B&'*17.;>@)@,A.,6BD?)$#:1>-@:,<=:>160:4D*D;A3D':'AH>9
@r2339
ATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACANCGG
+
.B4&"31%47D9"@?%D585':F4#6.&4C-HAC69+9'G!<4-EAC5>2&8E$DH=A0?B?"A&,?%<G%8>81("%#!F,',=+$@-;"<"8GH3%.2/"+)">6
@r2340
GNNTCATNNTNNNANTCTTNNGNCANCCCTTAAAAACNANGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATANACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGC
+
*"!$(!#!&!#$%!$&$*)!#%"()#(*+$$*+'$($(#)'"**%(+%!%)(%&'""!#*#**"'!+&"%%(+#(''&%(&"&)')&#!")#$'%$!')+'*"$+&))&#"+!!)$#!#*#'*$%&)((#"'(*%*%+"%$"(!&%()#&'+%+'%$*!%(+%)%!*'!'%#&%"+)#""
@r2341
GAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGNTAGTGGCCTTTATTTTTCGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGA
+
;(FCAF@;+)?A@G!EA)83AD4:)2$G>G"#)C*'E8"=77E676(D+>5((-"'<7-2++6-!1D%):&?*"E.E8#84%?C+(%+$C8=!$&D>AG&504#E+!"6:'46,(F>A#BHFB3#FC*)?(!
@r2342
CNTCCATTCNTTTGTNAGGNTNTTTTANATAAAAAGATTAAGTT
+
!$)()'(%*!&)&!"")'#!(!+%('$*&(+*+()%)!&!!!#(
@r2343
CTGGCGTNGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTG
+
$!"2."=>;B=F9?(1D-A!//A'"-GB,;700'1A0&7C-:642@95%?E7-?.-'+2D8!2;4"A.F=
@r2344
TGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGT
+
4F%H0?3F$*FF3=;.6;7A?!>+/<:G%$C&D5B!02%/FA;.9->/@
@r2345
AANTATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGT
+
@4&:8B*H&*B:63-=%/!BCEB+E5*:-/6B"""FB.1=5D!(?=1%+G#14'3"F8F(B'(AGE''*BA
@r2346
TCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTNACTGTCACCGCAAGTGCGGCAAAGACAGAA
+
25C"8@D==>G<6;?42:G>?&/=6%F@&H$<$"0F#@&CB#+6>$$46;?>/+7:)"".C-91=4G"DBD(:7&A(/G,G:3*%+A6(GG/%9%1!7726@#'618&'C/@*!B%!#B9AG8F=+3;FE#!13B>0A413-"
@r2347
ATTNNTNCNCCGNTTTNNNNATNTNNCGNNCTTCNNGCCGCNNCTGGCGCAANNNN
+
$"$!!!#$"$""$#$""!"#"$!!##$#$$"""!##!$$!!!##$$"$"#"#!!!#
@r2348
TGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGA
+
")'-9$1;9H-,):8B$G,+#A:5F)(;%*8F(F93#BA=15!4:C;)""9A.,0:"B$-.2G7&@9F3H.=-<81,@'E*;+71E</
@r2349
ATGATTATCATCTACATATCACAACGTGCGTGNAGGCCATCAAACCACGTCAA
+
*C6%?%3*0(H5D4@%*&=04$'!5<)+H>A8*7*&B:-*8%,0/3*772=F@
@r2350
TTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTNGGTNAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCT
+
G'050,;/'7$#')(3@BB:G+"B9B!(;).65@.,-E)GFD>4>@!HA/C..*<,&7'':;C4).,#56)C%E$)?(0%*+F.9D$>D%G#EC53B0E10>G"GFB5A?*3"93&!%';E5/F7+-0(770$A6%9/@#074>6B
@r2351
CAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGANCACAGAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGAC
+
$4C?&86C8'.%;?-8(+07,.>B$2-:;%@5H$*5/7D#%)D%+2,G(#((G1'6BB*%/,0&-:B.!*2D,?FDB,B/B.-B<#0>;BF'F(%$0C/;A.4B43?)<=,A=<:G,%A"90,@D/B$<(1>*6.6$#B1#6B()F(*7*.EB23).
@r2352
GGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTNCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCAC
+
C*)C-*&/=9%1-G@7&$01"+F%:5'$H8F:%EFE(;%!>8%E,:4D0:#?5<7E9<-<D<")<,(9':>7A2/1=82C="@,&-9'@3&;&8*43%/$:+?A3#:?51*').+E4?*E(')3@H%D"4$0F@F7!6*&4BA!>*?A#0#$A9%$*0."):9,A93?)@5-,G$!B/!726F3'1'?:%=0/'-C8C)H7/*)+*2F2).=7?:$6A?".,$9<15356&6D$D38..;E84D1F
@r2353
TGCGGCGCGAAAGGACANCCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGNTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTT
+
"')'$+"*%'#!$&(%+!*'!(&%)!$(%#**)$&+#!%+!#)"'*!*()$*'+!%&!*)$)%(!((+(!()"!+&$&%(++#$"!#"'()&)*+'&#)#%!&$!!++*"!(+(#!)
@r2354
GTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCA
+
.C:&4.7>(:C?;)C*(=47991"2$2A01#,,"%#D$<@0%#DB$@.12:
@r2355
CTACCCAGAAAATTTCCTCACCGANGGTCAGCGTGTCTCAACGCCGCAGCTGCCGCACCTCATCA
+
&DB)B0=91*8F>=<704FH(5483(&A4+))$DG$.!3??D8<?F*1:D62=08)?#$D1/*#?
@r2356
GTTCANATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCANTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTG
+
E6)H<%(?=((?<2%77D9F8&>C!2?7H1+BDE-(@G1+$+>-@0#381$?.#D*?EDAB?$:@C?#)75$%F:2=0H$@)=%2><%5?."H67%(:98
@r2357
TATGATCCGNGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTT
+
0/9DH2'F'0:#%,E!+(!2:!F1C.F)18EH==133<9.G5'G:B#%2FF)E?&,!)')!,3:45@@:BCA4A/.0,52)E?"!6&=2+()<2./(.179%(;!C9!?::H-,G+:73@.*1%8-"1%,<?-0%
@r2358
ATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGG
+
=:0;H!F:FA/:+C4#1A44-<$.3BH3.G/&3-HC75&-;BB
@r2359
TGGCGATAATCGGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGG
+
C?':93*81=<6>,40<-:F"H@B%A#0!0#=>/0<<0';A!8<H,C4?0*E-1;6/::,7F;3B#&/.$,9!1/+.%
@r2360
NAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGC
+
$8A$<&,#C5@6.!:40*5<E$@,5<"85G1,+9>""1E@H*"C%39=B)-+7D
@r2361
ATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCC
+
76(F-7=F.//%00E.C&6+""/0:8F9)&-9.6<B,!@"59A84-56*02H="<H.*G88F&=1;.%%-%/+,%:5%E(<+0#F;"@81%.,GF0,F3<!;C(7&3(92'G+(=B(;G*6$@B%<")-0H70H=2>,1#&D&(?2
@r2362
AGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCA
+
<5,!&BC4.)0/!6CG.93#HD<4?1*%;C3&G*-)H%*836!E)<,H(8E;:H,##9F%G.9(/2)+'7):A"!<"-,(D59)
@r2363
TTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACAATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTAATC
+
)9=:$54<$67;#*?02@0H447"4HD.*4239<A(B=F=(F$5C>DD4)!@&>0555>"F8BC8H!+2'6G"@7/F!C(?"-$1E)9,6/(F(@';ED9E5,@/+;*)D48<%844A84:H%()%!C510B4<D01H%(;)HF)-:)25AHD8
@r2364
CGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTT
+
%+)&$**)$%)'$'#'#!%'#%&&$++)&*+(""($+("'#$(!'"##$!()*)*"%)+()#"'$$+)*()(*)!
@r2365
ATTACTGTGAGCCATCATGACGCCGGTGGAGCCTGTCCGGGCGGTCTGCGTGGCCAGACGCCGGGAGGCGGCACTGGCAAGCAAC
+
#+)$&%(**)('&%%!$%*'**'!%+##(!*(!%(##'&&%!##'))$"!')#&*+%"'!$*($$(*%#&#")&()'+%'((+#(
@r2366
TGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTTAGAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTTCCAACCAATACGGCCTTAATCCGTGGACGAAAGAAAT
+
HH40H4;1-E"F1<A'?.<#+A&!>63+H!-2=?C0$1,&:F.#-!+2-/<*G#687C-F@?;?@>5E?=&=&E'-,$7-2C>99A$!#-#8-F6?9A0$&?9A8,6CAF>+5@%+*-(:6GG3"4*)=!C!7;:7:47-;DBA1%@@$)>)0>G'.E=;H8;GE94?E?,:?1HDE2<4#6H>3H+8
@r2367
NCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATAGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCT
+
!(+%!*#&$*(+#*#*'%)++!&$$+()"")(!"#*$(*'%#)(*)"$($'%$+++(+%+*&'&*!"*'+%
@r2368
NTNATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAACGCTCCAGCCCGTCCCTGTTTGTCCGG
+
%51C@DC,!,:<8F5%4776'E/=7>D1#C+18&62$&%:<<B8D$D)5"-BG;1%0>,A34?$C1+4EG?8+#?-H05534<;&-3B4=.:1
@r2369
CAGANATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCNGGCTATATCTGCCACTCATTGTTGTGA
+
%."?6("&4+E6D!@-(1G+"'4E9:'5%,#$2(H$!&"F7++E'DG#20&36.A-5D57#)$00*:<*94<3,&'A@4"2%"D>&
@r2370
AGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTT
+
EG%&%D<H<+$D2E'4E-4A6'C<<!(3>B7/D-7133;-.68
@r2371
GATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGNTGCGGCAGAA
+
8-=..CCE4&!!F.+>*"<#@>/B?>/75#D6?$!"*C+@B%2D#D0"D;?+=.@1!&4!1:<*"'G#@8H(B#89E2@/:68G5AC@2//<C43=7E$'H/$D*4%,-:35@7,2'#%+=C$&"<%0DD)H?;6C3<.#@$,,66!D1E)2=E&8@1.!,H/+@F;92!C06,B<28#D;B7.-0&'%,;=28'.@B-?$G/'97#,
@r2372
GACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCG
+
@##./::,CB;FA,6#E=#1(>7?>*4$B&(3E$'7$*<,883H-8B<#30$D;!5:
@r2373
GGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCNACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACG
+
)+"&")%&+"'"$&%&%%%#"#)''#"#%*"!$%)%&%#")&!()""*"&$(#(#$$!!*'*+%!'$("&!*'"!'(%++&)%!)""##)'+%%!")$)"&))&+"#+##$)'%"$%'")&*)!&(%!&#"##&!&)"'+#*%)#(*&)''!!+)+%%&%*'#)!*
@r2374
CTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAAT
+
/%<-$B(!?;6<3,G?%!BD1,8$9$A4ED<,>()DG/CE2A6C74=6H(')E%,0A2HA75(E0G3."7"%'&/'4A$-=-C%+!*:7<0;%?'7"8*.(8
@r2375
TTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGG
+
%96!+B@?*H<C@7/E2:?/:6(D$?4F!#(##H5<6B'571.
@r2376
TATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATNCATTTTGTCGCTCCATGCGCTTGCTCTTNATCTANCGGTTAAAATATTACTTCAAATCTTTCTGTAT
+
@A>9&&'.$A/7F)C5,;9.!0'(0;-%(#+HB:"6&D*1/0!06(3;&'$%HF9,'9:;<D'@6;4>F:8.*"H4(-+57:7-)4=!#*36<6A%?;5;(>!:3,E1.02>'@;"$(*=';
@r2377
NAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTNTCGGGATTTTTTATATCTGCACAACAGGAAAGAGCATTGAGTCGNTAATCGTGAAGAGTCGGCGGGCCTGGTTAGCCAGTGCTCTT
+
%0;E5"2F+@>$"=$.5*?:!3.'E6./!#C@&9>:1"%.<&041,A%D?/@7"-HF%%%D%A&3(?5)D82EH2">!?15>/GA:'#'??)=EE"3=:9>D+*F8+15AF7FC#D-/(7BG4H>>16$2%#=%*3;0G
@r2378
AACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGG
+
;GE;*@5'H=;*4+$D,F&C%E?+8>.!(#4F//=D3CFF
@r2379
ATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGG
+
-5D28(3B)3);)>C@H%1"+>"?@0"A&)4AH24A.3..>/,@E</%8EB5D.$@7GG90C!"!HB!=4-#@!-8+*111'FH/
@r2380
GGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCNGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGA
+
EB(6#AE)9%<507D!&C3&9=(048*2#%>G9A;*@>">4+5EGG5<-((A9'%*>D*CG3B&?AF<%5B+:)-"
@r2381
GATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCGTCACCGATGGTCAG
+
:=2BF,""A,#5)ABD?..2#*;"5B1#.EA-2EG5*D>.)F$&B;H,!76(??GC"0$>+1";'*0
@r2382
TNTGAAAGAACACCAACAGGGGTGTTACCACTACNGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTA
+
%(:DG8//B%95%/3DG#=8/(F@A1>)9A1ED')F59H>8.;5/&'B,?5'-=8-6A&+E$/F':50<-3>="-
@r2383
CATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAANTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTGTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGNATGGAATGATTGGTGC
+
#B.5-!5A"B1;'4:<#3>$<D(102+">F!41/?,%E#H)@%"*%@B(F+B8052AF#<%58F)BA;-8/";=/8,'$$$'(-,7*B.%C;-/#E$.9'>&C2')'?8D8@/4EE57(D1,C33>+-(<%>%B)=!D<05*;H.95?&?8+E/#1/6!7#.!C1B4E3FGH%5@3B33C!$/!9(HC>G#2%7)9F"-(=98C3(0-A@<D%<2G)>--!E;2#-86"F7(6!35?"4,6537,GA(&&+(:6>*/30/8<F6&>;C).-47BD@+CB<):5;&;7>2==H'F(&E$)>"*6E'*)/2202$45B6#,)AA=BF+#>0A%"C8<,4D60=EH
@r2384
TTCTNTTCAGGCGTGACTGTTACTGAATCCCCGATCATCTATCGN
+
#)!"%$%'(++!"''+)(%%*"+&#$+$#"!%!&!)"'$#)!*($
@r2385
ACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAANGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGNTGGCGTTGGCGNCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCA
+
-2"%9&@()%*D:4@(+(D#7=653"&H>-;5@:E).F'<&+.#&HA*,#?$&0-;;81@9:"<96D/6DE%.6:G6/A3#)EC$+HDF?<,.!%@E%!;5*?B5+A'0F!8A3$$><)#;6764->$@*.A-*1@D?0:4?-5'!&G*8-E#D!/4.:HCD2+<9<*"F#8E-F9H',4(<><<#H>1(H:90$?DBH,5A-3,F/@%207/F#6A#DE?(@62CH'E?)2>:,/6%"<,#$/(<<.0G)"0
@r2386
TCATTATNTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATNGTAGAGCCGCAGACACGTCG
+
66*;-F!4?C,48,?>$,%"<F?9#!%8H@9$1'37?:1E=/,2:,24@B40B>B!B.AG3E/G:C1A6)91-22C!&")3C"@
@r2387
TGANTCTGTGGTTCATTACGTCTTAATTCTTCGTATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTT
+
FF+>GD;")!1B4B1;'/AF!AH$?F!6.%47'AA:96##7=F9C6A!!8/8AG=2.=%99;&3@4*!+<,,829+!3=%?F0C0B!D-(@;C2"3FC9#DG(!:&%2/6<("#AG?ED
@r2388
AACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACGAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGAGGG
+
9C3>%3B:&4F"E,28$B44E-#5*=B*D>B7A050EC@)?7-*($F!;!5<<E+2D(/!6./1'2/>/?#@9&,77"C1"<#=29630B!&1:2GE4&?*07F>
@r2389
ACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGACGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGGGGATGACTGCTGC
+
.1'B3*7>?)07$BA(D4/%9G&BB%"<+D&#:(B!D3;:E&F,G@%03:<42+@#:6!#<A-A(<A3@#7&":+4*D2-!/A84->C-))9,@D9!<$2#9,$5;E.%.+8,8H#3!6&+<=<2)88C.?>8#(,"+57#7&2!G/67,C?D#E(.%.9D?/)5.HH8*!'&6<C=)2F1$$?"(3$H<)/8=-8E1EH,<B<?15'$9-)4+D1$!H,>*5+DF0A$2E50@6")29F"A=!./1,H03EAH6B!
@r2390
ACAACTCTGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGATGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATNGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGNATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATANTGAGACATTCGGTGAGAACTTAGGTG
+
H0AC5<)7$69(2!8AE27);F%:3@1:-!86<:9%0&0"%5=!$0#=&!'%;-3G'?@)/8%+%8*F'4=0=*:)&2D%$FH7?G&7!+44A4.01&4#<G)16:*A$7)/H"*,B%DC3E1+'-2#-&,0+%=4B*2'A9393+51F2',H*!=GF-13/2&(!6&@/D$B';A8"A=.+/AG.A1H!A'5&3.@?>C&/BC;%7"7(<2(62,;5:!0D0"3)?-7??C8E/B:*+F%?+.;2<BA5)(H:-01#B'=$B-8/G='F?@9-&&6>AAHG8,CF$3><H/9>>*@#0;*H9->B1".G.H!FCF9<-+C<A6GEGHG>$B/6F'!87HB&(+?!AA/2F;*B1H<-@65H1HAG1/=-)?)-9=-5B!+G$*A(+?4+0"5:E-,%0,C)&B8D0H*"896(C9#)>+1DB3//,3!./959A&"7&H/.)*.5$"*@;-;024D##ADG+?D/*4("(*@-'%$
@r2391
AGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCNGGCAGAAAGGGAAGCCACGGAACAGCGCCTGA
+
:8&=?5.%.$C+;@!%B39-3"'B+#)A+*+,>5*G"5H=/)/BF!A3G(D8GD'#5FG#-1B.G=A9:!C!E;!6B+4:*>.C>$A*/1?#$14(*',"F7#.?5!41/8G=0
@r2392
NCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCCCANNGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACNGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTNCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGNAAGCNGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGG
+
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
@r2393
NCATGGNATTTNNCCGCAGCGGCCTGAATGGCTGTACCGCCTGCCGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTTCCGATANTCCCGACA
+
%#*&(*#"#%%"#"+*!)""**#!%&++$&)%$#")#!))(!&!"***#''%$))#+(+&%+$*%+)'$(&*$**+###$!&)*($!*#*%+)('&)&&
@r2394
TTGCTTNCNNTGCGTGGGCGTTANATTCTCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGNAACTTGCACAAGTCCGACAACCCTGAACGACCATGCGTCTTCGTTCATCTATCGGATCGCCACACT
+
$#!(%$#%&()$$%!(%('*"%$$(++')%!%'+(!"$)+#'#)'#$)#+&'%""$+%"%)('#'%#'!**#%"&)#&"(#&%#%(%%"#!'&$&!"+%#&(%)'%(++&&))$(+"**#)+'"++(%%+(*%'!%$*!*)&$
@r2395
ACGAAATTTGNATATACCCANTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCNCCCATATTGCAGTCGCGGCAC
+
FF+:BA(CA?,@@F$<86"%."&)*.*@+>E!F.&&<B,EFB,@25589615+#97-#5","=:;.D#9@$,6B$@.CF#+8G66B>-18+=6'?@A30E$"$H?17+%?82G+%:<?9>39>!C.
@r2396
GAGTGATTTTCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGANCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGNGATGGAGATGCCGGAC
+
+1,>6E+0</*/93D?F@?9&D/.9C+<@4=@GG70%&-167C775$4'E#1H$5;-1$B+HF$6>,,H+7'==<)2&<=,/.:#A9)!.G/9E!:FA,0#C6>F+3'')G05"G8!!*;73?-,:CB<.-FG55A7FF<=?9<.=53B'!2)"
@r2397
TACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTT
+
H3F#=&9($B)C08-)A0<H74<)5-%HD2$E#?&1#F&,0-$3,(9',6/64C/#.0E:>0=#;C08AA89DFHF
@r2398
TTATGGCGGTCCTTCAGGGCGCTGACGCTGTAGCGGAACGGCGCGCCATCATCNGGCATCACCACATTACTG
+
89&?8285";FF50!58!B":!=<3+8H)FG9"./5C?*H%!,(E-<6(<6%3(B3&91;'3?.>DE"H3'5
@r2399
TTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCNGGCGGNTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCC
+
;!F!%:3'()-8@#(F!'.G!30"+!6;#*G$.&E($C/77=)$,#.9+=03)E7AGD+,,;E=49$C079&G"0GA/931?3#'%FA,2
@r2400
TGNACAAGTCCGACAACCCTGAACGATCTGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATGGCTGTCTTGCGCTGGTAATTCTTC
+
;7%5>>"11+.>E@H$?&,$4G<$*5?()H!)GB,E@!45$?(1F.59#@51-#,0"3$.&3H7-.H;@)5453+=#(;HB@-;11!;<;94325&=(7;#)>@0.A;5@7DC15$A)(@?/?"$!)/1%4*)F:D%"3
@r2401
CTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACC
+
;7=':!#-:4.32":3(H@E2D1@$H/1H$F@A$H?"+E%727(*8
@r2402
CGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACNGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGNNAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGNAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTNAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTNAAGTAATNAAACCGAGCAATCCATTTACGAATGTTNGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCT
+
60!$B3<B</+3&9A11GCC@#/'>93:+94'4'934D22,2GB>BD4,@6+"DG4?())!!791(,%D$#E%)9G>$$"H.+!*?9GFG**$/D$E78$A<8@=/'48>4-"4?B-:1=.!2<.(05B%?#*)C4=C+5'//5*1<0B2%!3<)3969'<50C*#@@-<6EG/5(<4DDF09"2HA1E;:<(7*$>C>0,80-'>&6H<+4%&>>C&9-66"$4/+9?G%"<(=D#@>><!?98*4D7?8:"&D+:A?2&3)?!F,?4;6(H8"?F5>*'/63&)A1D97':4%@&4HE:C&E25$6D80<9)7"2!)'HA2#"DH4;H8';H7?-4@#-1!=1:,8.6-03G69*G-!#=;.D!
@r2403
ACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGNTACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTC
+
50.-<(4%//D0>)%!9C+%'706!4'C?"6+F=EE(.75,-AB&AC=F(D)2->#!"<7*7A&?871HE1:'*.-C$<H*<?4?G?=B62*!,;+(E1$!);=/D;<2
@r2404
GTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGAT
+
B.G7#++@3C$>7.C!H;D6>3$$%B''3(2+'58C,9D<:,-F7G)&H2+E==80:0@)?<HFH91A6B=B7);&.F!79;*$(H*+70<7'2&G'--7E57??
@r2405
TNANCNNCTAANGTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCC
+
'"&!%(#*%'(!%+$"(%")"&""&*#"$)'$(&++'#*+'$)$*%"!*+"#+
@r2406
CGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCAT
+
H$18,C'+E<C'G(6(:*C0F2C)2A<;*'A#3G8><;9,G>'5@B):A3-)G
@r2407
ACAAAAATGCCAGAGAACTGAAGCTGGNGAATGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACG
+
68*":0:<HHF:#$B*G#F2@,#A+*<&(;#"H7#D-9$'%3B+3#C?8(2*::,8:9D.$'BCGA%@B=18F;)192!@+8BB1#14;->#,&&
@r2408
ACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAA
+
1:C0'5=?8?GB=H8'@38"?F@:4#3>(,(@&6"=-;&)/)$)166E,
@r2409
TCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCNCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATNGAAAGAGCTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCNTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCA
+
8>;"#$C:8E@)(=):AA'!A'>.FF32<BB;(A(G,H9CF*".,8"4!=%9,$;H@.C@2F7E1)H10=-(46(:-BD%)AA+"=$>C1+2+;1=>#-D/H(=3#5?B<?8>19?D.,@1BG0(36A.85:-5+#B$.D**2E>+10E"?5+(#.3GF13D9/;!!EC'$8+$=G!G#.:?$C#,>BB89'&*6-5-:F(8:@4;>+:F9*4BA27,-92$H7?.31.><:(4
@r2410
TTGCGTCGATTACTGTTTTTGTAANCGCACCNCCATTATATCTGCCGCGAAGG
+
$738'!72!?*G-!('/BDA6>&=8%%6.@C1,8@'>>B=*;*$E8(@E*'.8
@r2411
GCTCGNNCNGCGTNTNTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGC
+
)&*!#$#("&***('!+()%*)""+()&*"+$#'+*&'((')"#$('&!++)&'
@r2412
AAGACCAGTTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGA
+
?4+#E@#?2?9(-4D5H/<F+E95"-9#(.,B1$;,:)&/,@3(!?C5>7B<>>A)$3;F<
@r2413
TGCAGACAAACTCANCACGGTGAACNATCCCCGCTGGCTC
+
0@1/80E79#H>A%@B>B*5CC$(?'"/'021.@G@-5F4
@r2414
GTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGA
+
7.6"C?%;$"@9F"/63HAD(F;E(8'@,?B?@4'D,4:1A,2HGCD/"G566=9=CH1BF
@r2415
TNGANAGCGNNAGANCNNAANNGAGCNACGTGGCACCNTNCNNCNTNCNGCANNGNACNNNGANNGNNNTNNNNNNCGNNNNNCNGGTGAGNNNNNCNTNTTTCNANTGNNNGNGCGNGANNANAACNGCNGCACNTCGNGACNNNCANNGGNNNNCANNNNC
+
""#""##$!###$#!$""#$"!"$$#"$""!$""$##!"!$$#"#!!"""#"!"##$"$"!"$!!$$"#"""!$"!$$!#$!#""$$"#""#$#$"#"""!!!$##!#!!!$!""$$"$"!!#!#"#$"$##"#!""#!"$$#!!!"!!!"!$""$##$$$#!
@r2416
GGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCCGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAA
+
(8AD*C@>CGH*0)AH5%!:E8&C<1H5'H)D-((E'B"DG!F<C-6?062.@C?H%:1H/#0F?BH'#,<*6E>8;!$HE8@(9D$2,873.#A.C"*G@+39?!@@#%D-9./->!=$01'G)0'
@r2417
GTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTC
+
.8>#0'5H$<6?+9'7+B4DC@E@):@/G9..?1;-26B;A5+G4?%@E7+(*"(?BG1@CF1+(E>1'H99
@r2418
GTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTT
+
77H(!&:?5'<B;26'$F,/=0E(:AFD5%1B?1.F>B6%:"D#.G9)HF6#*F.(,%B?F/(#
@r2419
CAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAG
+
B:=<"D-E?'/-79E'42A;>6/96$0*9>'F)C=,G>9C45,50%=,<-(@*/6H:5:B9<C7=C/8DD9B9,
@r2420
AATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAA
+
.36H'"!F3<'%9E+!!G:>G42H#)"51%$8EE%!?2/6G0@+F(D??BE(B;>,4,DH$>%
@r2421
TNNTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCC
+
*!"?:<-!5$&''!'"$G#=#9//;7@!/-H?ADA@$>4-H=8D25#&-(!.DA>+90%8+
@r2422
GCNNGACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTC
+
#'"#$+&+(#*&!"*!((%'&&$**'$$""'$'''&&"!'$*(+"#$%!#!%&%'*+%(&**+#"#)&%)%'''%*'&$($*
@r2423
GATGAGTGCGTGTCCGTACAACTGGCGTANTCATGGCCCTTCGGGGCCATTGTTTCTNTGTGGAGGAGTCCATGACGAAAGATGAACTGATT
+
-$BH<4>D%B7.36:2/=866)418F>?$-,E/,#:3/E4DH:<(B7*+@#'C#5"G*EE21,(6:5B6+1@5.2C357C!/C7')4A3-D(
@r2424
AACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGG
+
+*?08<$6)C&8+25%8E"'2E!B>:'=E85?3@10#!*AE$4(?'%BB.H@%F.@>+)4?F/31@'D'3<6*00;'"(,+(E;(<9:&:E-4'2'/D=17"
@r2425
CCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAG
+
9AD+E.D6F&<>8D#F+"'DB%A@:7//82H?5<;@5>H:3?198+!;F&:(6
@r2426
CTCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCA
+
#15E1$!';&&FG7(C63$/)&&,H64&<$7>6>&+><%.HE,#G<B$6%13D+:&"F%;,6:
@r2427
AGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATAT
+
3E!=%/9.%C3;!@A=?-1E(@,=>)'8G(9*7*6%>F%:5>FG@/9B1==)61:B,6&6=15,+<66,)(#=9"3$@;.*"=01#"/GH?8&E3E7<
@r2428
TATTATTCNCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGATGCCTGGTCGTTCAGGGTTGTCGGACTTGTNCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCNGAGCAGGCAATGCATGACGACTNGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGNAAT
+
5A2%D$G25;6,B*"<=/2F'0*B")'$;$(>,2,&5D(<%:0?DD*98$"+A7?2/>2'*(.<$,A6C:-3&$6#"F*5AG:B<$11)*7%'A&,0,EG(1.C7/((*A:))-2=!H+D-!6D5F"#>E'/C')D4B<+2@!9FD&5&.$)3.?%#(:="5C/-0*E-F1#B92E0#123AB-,%B2,,?,(A#9A:+'H,GD7E0;G?A*2<$#2AFF')E..&:"+$CG8D3H!,9&A$'/FEBH,@6=B1D3<=:=:,4#@1//5>%0%7"-0:-FGECG@<E'"D;@;76>%1!&=!H<5&C@5>&!"25H))BB;*,)$@'A;F#0/37:%C)/?F0;0+E:;#B-":>)HF0BA>8/:;0<9+;?-?+HD4E@A'*1F07?E<=:0"@*"+41@0:=A%0H'.)*C1AD*!6>#!"
@r2429
CCAGTAACGCGCCCGCGCTTCCGCGTTNACAAAATAATCACCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTNATCAGCATCTCCTGCGCCGTATCAGGACG
+
#*A."74#;80/)1;9."'7*3ADCEA)*.+$@9G!9-(+D$B6!1)-1)CF'>1@;<&B#$60=(@2!B7C;G?4B."6C3)/$26*('$53@<#>,>0B'E@39.F1AH==<6&,!E*%2"
@r2430
CAGTGAATCCCCGCATTTTATGCGTTTTCATNTNGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATC
+
?%:+&/)):@(4%078#'AA8"'9'$><-)9663.#16H?40%G<$>C5@8#6:#=+9/H6GA$=H8GH:<52E!74?-G+(%9"G9G2(9A(?),G:$(+E9*-8&4$BH*('0B1>6<>HF52#>426);:6#2?
@r2431
TACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATNTTCACAGCTATTTCAGGAGTTCAGCCATGAACGNTTATTACATTCNGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGAT
+
$@/=+-:#HDB;4:BAG5<F(2A*1G1#?C211E<A&2*!>H?G&CC'C1D3AB-;A/:?'8AE9<>(?B81:)&"<8;)(F=?#C24>%6:8FF4C"722<;>=5!-H'85E2.8DD:7/4,<+;=:"7=<7832'(:/=/::=D<A>1*-!2?ACB8.3@;!F8BG#D0H4;%G=H:&5<72<18H!'(*"0F$3F0?9@")BA08/(5/),G13A.<?8EF8D!9(,6H?'(;/1,E+7%3)+$,"$=<1):39.=B8,!?'.#9/91/FFH/%%;#3*D*0>4D#)1F(<1:09<9H!0==0//H3@9$E:3
@r2432
CNTAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAA
+
&)@1?%(=9>#D0A%@3;%";9@<'8=@%<G<44A2;)"E2<0F)<2:/)0C,925*#?'0:?<A0
@r2433
CGCCGATGGAGCCTGTCCGGGCGGTCTGCATGACCANACGNCGGGAGGCGGCACTGGCAAGCAAC
+
1$.C51:F835C>F'$3F3C((76><=H1)0-F1F2*B/A&3:,3(=''C3,#*0(HF@&-HH)-
@r2434
CCCGGCGCTCATGACTTCGCCTTCTTCCCNTTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTC
+
6,/F8H84:80)0AC?@/)A.B"%7(G!5E?%F"-1403?07#?A731,GD6%BB49A5:A)-5E9B
@r2435
CAGAATGCAAAAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGC
+
6"5,(0H21?&%07%HGD$3)#<(21342):)"""G=;@>,%+5F$H,6B;*>
@r2436
CGTCNTGGGGAAAGTTATCGCTAGTCNGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCNTCGAATTAGGGGAATTTTCACTCCCCTCAGAACN
+
$%)$'+)#("'%%+&("&'"*%"&%&+&+&%!$%'*&&+)'*+)$++')#+!!+("*+#*"!!%%'#&)"#!+#('()!$'&#!*"&")$("&*#)(%&"'%)(('*'&+&')!*!%'*"'+'*"#&$!$"!&$++*&)!+
@r2437
GGGTTGCGACCATCCGGGANTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATG
+
F3C</.A.4&<#9*::''<-$/92462H#D35='.74)025#,=,>.6)$A5)*$#G?C&=%20;)=@'),54&#)4<:
@r2438
CAGCTTTGTTGTTCTGTTTACCAAGTTNTCTGGCAATCATTGCGGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGTAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGCTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTAC
+
''"&')+)%)%+(!&*((('))&"$!+!((+*""$!+!(#+*'!(*#'$+&#%!$$$$"*'$!$(+!)&%+$$&'%")#(%)%()!$'%+'&!%)$#')$*#%$!+$!*#%*%#%!*"&)+("!(*)++""+(*!('**!""%##&'&%(&##&*#()'%&!*%#&*!+(*&")$"#+$$$%!(#%+%"&%##(+"*(%&(!!$)))#+(#*)")&%%%'&###$'!)#')(#)!&'(++$"!)'+&#("'))#"#(!$'$+&*'(%%#++"(#""#%)'&%$&"+(&)++&*+%'#'##++#&%*$(")&!$#*))#*)*"!)%"(!$+*%*(!*#&%'#)*##+'$*!#(""+')##"'#)'$"""((&"**&!+(!")&!%%&$
@r2439
AGTCACGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAAT
+
$)=+-%A&*"<E%B+B4=DC%?54>#)#.=!+=11#H-:;7"F8(
@r2440
TTNACNTCGGCAGCCATAAGGTGGATGNCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCG
+
&#++$(*&+)$#$'*!)"++*++**#)+'$+!'(''$')*"(''+%#(%#)#*""$$"'+(&)$%+$(&'&(*&(%+!"
@r2441
NGCTTTCCAGTNTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCTTAATACTCACGCTGCNCGTTGAGTTTTGACTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGNGCAATATCCTC
+
!"+")"!+#%+!&)&*)'!$#%#$+$%"#%!*%%+%$%#$)**&$!($''*("!+&*$"&&&!+())+!'(**)''+)!&"!'&)*))!$"(!)"'&%)&!+!&"(#%$#*)"'"%'$*%$)*%!%$'+*!$%
@r2442
TCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCNATACTACATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGNTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAANCTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTNAGATGGAAAACGTATGNAATAGAGANTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGANTTTAGT
+
D&04%-"$2.:323*!1#.%/8@:D&8"6"B+:$?/%8=-E;2'>H4*H1:;3D"*E2:4:DC<*$>-$ADF%680@A,!+G'EC*A->2H&0%(FF<H;$(8%:*)-;-'&<,.0'FG7.4/97?<>-C<4G??(#BFB43H>!!,C*D!!'5(CD*<*C2*%<F0CBG+46=C*/4)/G$%-'F.!A$9!-A$:1BA>B?%1-!B,57%0HG4&+G><F&6+'*#H5G"D6C%E;H%:3;7?>1,<H.0A&)@#(7E>*<4&A>+!H02>*/7@2!<!%35&6%<B%@.74&2B;FC=)?D-(E+C-<74FB!-%/FG$B%4
@r2443
NANATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATG
+
%"!0073=31)9#(,71C*;'HD!838'>06->==3/'B?#
@r2444
NGNNATACANGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACA
+
#&%%/5>B6-F%9186%49A3+4E,BA($)3+=4!BF+)C/00B?%60F+E0D;%6+!..@H)A.:@>?;*BCHE.10BG*!EG&H$'GD*"E#;#8<@'=-&!1$9D82@C(5#'9+C:81)>@:3>.A.D>%-*6*H*D05H':7(-9*/.!=B3E'H/!4G$E37+H1=0DC0!6+7;HE!;#53-?$(<:@B'),)H6"7>&DG%5H:F)=>)2?9%&4*HG5**E;2+.G+C<HA?5*(F'=DE
@r2445
ACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCG
+
0$*5(?&>H#A?(3B=$#F.CG7+-))1.#/@/1#?=G/>))1C)D%0HG/G>D/4#3;9?@>.7%:"4,58D<1;EB"819"98'7E+A0*35,9&GF5.86A-CH$4C#$7?=1E=FC7!7'-">:9":-
@r2446
TTATTGCTGTGTTGCGCTGGTAATTCTTCTATTNCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAA
+
31*=7<)GE&-/AE/D>&6?*DD?!(.'+&$H1<99)..$AFH#544/?(;7A:E1A-7<;,@*2&D"A5+>
@r2447
NNTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGNGTGNCGTGAAGTGCATCAGTAT
+
#,$(;30'$/=(E'9!?<C;,D!@$>E6D8D$H+>:FD';G>DF%8B@=FG&>8+G)9CE!-01?0)A2#7F(-!58&."-)8?4%F0>/,#F+<A4=7=%=+.-C8)7?&/=D,F)DC;6%5D7-7
@r2448
GCNCTCGGGAATGATCCAGATTTTGCTACCACCATGACTNACGCGCTTGNGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTANCGTATTTTGCGGAAAATGATGCCGCCAGCC
+
**)#+$#%%++%$*&(%&'*+(!"")''*%+"&)**($%(#$+&"#!#)&#*"%%%&!"&"%($#%#++$+(#)!(%%)&%'#'+%%)'&*+)#*"(')$#%(#%$'$)%&!#"+!*$'!()%##!*!'&*(%&&*!#)!%+)()!+'+)$)$#$*
@r2449
TTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGNTTAACTATGTCCACAGCCCTCACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTT
+
')26+G.&@2%6)E:#:2/,$<77&<+1F=-'#>$=20%G3G!$D(7%(6H4/,-B.#5%5:+7E5F>(26GG87:28(0>)H/B#11#-..E0$%DB)7:E3%8!'+</<E#8*/)/0@)42DD&46-"F&F2D2=C*:=/F:@)?G.EC*1;1$C8<."/:4*(1<F,2175.++DDE,@D.D9E@CG+26;)D2/#6(#;!%4A.(<><A:G
@r2450
ATATAGNNGGNCTCCTTGTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGANAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCANACAATGCCCCCCTGCAAAAAATAAATTCATATANAAAACNTACAGATAACCATCTNCGGTGATAAATTATCTCTGGCNGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTANAAATTAANCCCTGAAG
+
$')%*$*!!(('(!%+*#)#)#")*"(($!!"$*#))##!*%**"()("'+!++!$*%*+##&"+!##($!!)(&)%%)*"*+'()+$$)!*&$&)+*(%)&$#)''%")%'")**+&%*'&%*##+$)**&&!)$++)"!!&+#!%%!(%*)&'###%&*#($("++()''&#"&%(!(!'!)$%"*#*&%)+'+%'%$!%'!!$$)!#%$*)&&*"%&%'++*%"**%$")!$(!+)!+#$&(#)#'$(('$$%(#$)+$"%""(!$%&'&"*+)##)()!!**'"#!!)&%%("*$#*&&""#!%!+!+$'**('""&&###%$+!%#&)**!""!&$%$"+##!#(%*"
@r2451
TTGGCATTGTATGTATTGGTTGATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAANCCATAGGCATTTGTTATTTT
+
+7*<*."DGE26.++.$CGH9%!+/>4;5?C=(4.49E4>;@GA&:);&!8''&>$$$4G<!.3:)C,;7/%79#9*H:<DG)E&0"(2;A3'+
@r2452
NNCGCNNNNNAGNGNNCNGNAAGGNNNNGNCNNTTTGGNTTTTANGNNCTNANAGNNNNANCNAGNANNNGGTNTTTCCNNCNNNNNNNNNCNTCNCNGNACNNGGGNNNNCNTGTANTNNNNNNNNGANNNAA
+
"$!#!"#"!#$!!!###!!#""$$"!!!$!#!"$$!$!!#""""!!$!"$!""###"$##!!!!#"$#!$##$#$""$"#!"$!!"!!"$!#"$"!$!#""#!$""$"!"$"!#!!$!$"#$"##!"#"!!$"$
@r2453
CACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGANGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCA
+
$),E'*:2A&GFE@/@@A?5-8>.=,4@8&5#?#D7G?#54$E37%"%1/;AF#FD0&A1B+C*94H?E'8;?&-%/<1G.#5H*&(+H!<,1$!B/:'%8$%&&F;4*0D5-;@86;$<0%-4&2C@>9"--;$6"+>02/%=-D$.<@,%C)+$3/2B
@r2454
CCNNCANTGAGGAAAATTTCTGGGTAGANCGGGTTTCGCCGGATGATGGCGGAAGTTGTCAT
+
*)$"!$))'$)*$+&%%(*"+%!'!*"!""!%"#)&*!%+&')(!#$#$)(")'&'&)!%&*
@r2455
GTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCNACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCANAGAGAAG
+
803-1:*#D=@#E-%8$(H.,@2@H#+'!;2073+#<+&6D6")F<"7*A(E*?B(C;-F)GG8;'5F+-;:#/3/D)&F2+?-GD0=51(4)?!53EEB
@r2456
NNTNTNGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTNTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGNATGAGCA
+
$"'!(""('*+)+''%*&%%(&*$%()"*%&%%%()(%%"$*$$"+!+#%#$&))&'!($)'$)%(####""*("(%+)))&+)+%+"&(+$*(**))*("'!$)*$*)#''*%&+#%%+''+$'$)&$'&'+"''#)%#$*'#))##+&)*%'
@r2457
TCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTNCTGNCATCNATTTTTTCGTAATAGCGCATCT
+
1;="878$!"&!&7'?+C51E;$8GC<H/F%B!5331"B2;%>8$+C#C40G7..F#!"@+$A#A*?58C13A/"$9?9!?
@r2458
GNGGAGTTTACGGCCACTTNCGTGTCTGACCTNAAAAAATATATTGCAGAGCTGGAAGTGCAGACCNGCNTGACACAGCGACGCAGGGGACCTGCAGGAT
+
#'6@3%1<=1!=@%4<**%?*"'B$CAF@,0+#F(F37,EB>&5F44C9C9,1G@#(0$AHH<,CE#);G94(7D6&>.%E80!H%;>4/-#,-*:%$*7
@r2459
TTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAA
+
3B+-$=#F*250F!EA7:$$*/906>3(2=.@$./C04C1'
@r2460
CACCCCACAAANAAGCCCACCGGTTCCGGCGGGCTNTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAG
+
-$>%B3)=&$4=B3@(.:FFG,@-943$3F@@A>>?+F)>H;/:9C=@/,<=G0>EC1F?F;!1"@/H#@E!?5++43F9.@*3D=?E0?1@B<-#>+G+0;*:*0-7:9?H6,1'/3@4=>#--+&G/(A#B%6DD"/;
@r2461
TGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTAAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTGCTNGATAATATTCATTCTGACGAGTTCTAACTTGGC
+
/+55&-,3>,(?#!;8?.+5/F3#<)$9EB/)?'709/!71D(:0>9H':G75'/?47)&032$(G4#%/-B2-FE!&,15;$=H*B*HD8@20C/'H*64AA9'>&E?-&>>)$6?>H$EA)2B"8A:BD+.)&"8H:(<
@r2462
GCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATA
+
*B)'.7"3FC"6.1G)-93,F");1@FFG07$9++)9B&6>G4"/$=E,,CAC"+=>A16@D:.?/&=3"+H:8
@r2463
CGAACNACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACNCCC
+
@E9*B2E#,:4C$.6/'!(2#"')+:18"+8=>A&+>8A?9;"!11@F($!$*%.0@D4F(<9/0@B#C64
@r2464
TTCACTCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTAT
+
7120E$=9D/1F*G::7<0#&;"43AF78&8/9:-;$C5$2?E99*52BB05*;"HG8-G5E1C),!-?
@r2465
NNNNCGGGGCCGTGGCAGTCGCATCCCAAACGGACGTTACGTTATAAAGCNATGATTCAGTGTGCCCGTCTG
+
!#!#)&"+!)+#*'$(''+*#$'#""''+%!&($#!*"&#(+"#("+*"#&#%*"&!'!+)+)#)%%!*!"!
@r2466
TTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGC
+
&=8E1123$9-<*4=';6293')B7/5;(2$*$H0=)"/93E.#-2$;9=6.$'16
@r2467
GATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTT
+
%:H"#*1/E0-C:G.+E65/F$#6#G"54=5*(7C#F4:?(9*DC=/FD"?)(AC<=B)
@r2468
ATTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACC
+
!@<&9/#("0%+@>##3;=H3;,;+G=D/91&E>(=E9>9A.),/)""91?6*6H/C>96&*+ACF8EH45D3FF67:.8D
@r2469
ACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATC
+
1@6C'=B$"F@AG)!32HH9%+*HH:!C%)!)+#$A$0<5-,D;,67C#;&#?9/6H
@r2470
ANCTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGAT
+
$!#+#!%"#$""!$#"#&"&+&#!#$+)'((+("*+'&+&%*'$#"&(!
@r2471
CGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTCAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTAAGGCNACTTCCGTGTCTGACCTG
+
;#%D+A"G$(8;F23/BA?!3'(&B&-%C?+5;.CG4/F!1?;G#+)15-D2<=6C:8C0*.-56=4/>957=!-.A;+/%B$4,G8:)!DD"-8--0($!C3#AD(9)8!&:F#@G6&=/8A1A:D<?6.&<)=C-*&F#:$A.+24;,'35
@r2472
NTTAGGTNACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCANAAAGCTGGAAGTGTG
+
$6@0D;4)EF;C(8=:1EBC*9H!F2483F""!F6=B;<>++6>('D+,#00@/#>5#843*&H=<)C
@r2473
NAGATNAATCGCTCTAAAGCTTCAGCTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGNTTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCANAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATC
+
"''''"+'($*+$()+*#"%'+')!%"#+&#)*#"'''%")#!%)'$%"!+!*"**)%*!)!*#&'%)&(&)!'$&')(*+%!&&*%!+*)$&$))!#)+!%(&)'+""#('"(!"##''+*"#"*!'!+)%%&#%&&#"'+*)&+*&&$%$"&"##"'+&)
@r2474
TTTTATGGTCCGTGGTTNTTCACTCCTTCTNAATGCCATTANGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCA
+
.&&1@8'4%!1@:A>"&-'B.-&!7G3F:33-B-/D'.H@#;8*AHF>D)@+@C;D-!1E)4)9#9;D80A.(8,3,C0<97',H31)?418!@AA*HD:D%#G$$=.;FF,,='%<+;912<)+'-$824#=%7;80@G=#1<F:&"/-*,/<**0:A
@r2475
CGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCAT
+
+>27)1%&>G%;B6HD<9)'+)?74%!+-(5'GG91!?B=,4>B>%=G
@r2476
CATNNNANAGNNCTNNCCNGNNTNGNCNNCNACAANNNNNNNTNNNCGNNTCCNNNGNGNNNANNNNCNNTATNNNGTAGNNNNNAANGCNNTNNATANNCTGCCANNCANTTAGNNGNCTTGANCCNNNNATN
+
!$"!""$!"###$$$#$#!"!!""$!!!!$"$""!!"$"!!"$##$$"#"$$!!"$"###"$!"""$!#!$!"!$""$!#"!!"!!"$#"$$"#!#$""!##$$#"""#$#"##"!"$!###!!!!##!"!!!"
@r2477
GAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCG
+
-=##78@994-CE62/F0@1!"+C&FA(:?$<!3#:)/$A:/#,?')?6,/,*GH>CE9G($%>6=71'1
@r2478
GTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGANCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCT
+
-4),1'C,DF&67<('*9/22?<=6."H2<-,):%0B*%.-'1;1D,44:=,>4;,$8:"8@+1#!*);$#=%,(;:-&("4BCC9#BG6'5#;AA:)+)#-=%9-+/":2>C0!$74-50')E+$H<!:9:CEB05#<F2'5F?#8#F',?E8//*
@r2479
TNATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATNATTAACGNAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTNTGTCGTAATCGNGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTC
+
*,>=@=0=4?.6=/(/B,235F)-$H@5$G7-<>@DGB1A=-?H,6A&$%BA/>F5)&"2H/@"1:98;6/B#<=H:*@:<3<,!%>=$!82F3%@61:C!$-,>)8@B8,/B.2#81E3C*=H#29@0@75)-7!$2B-:0H@4A(:<?EA&,55&4'47&+1>1%6EG*8=@0HE%?=G7:G'-F!!E,E#A>GGC'A73G:0
@r2480
CTAAGTTCTNACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTNTCTTGA
+
5G&?"(@"F;7:0>0?$/#0H%03@02!E)>5+$AC*+;8*=93E1B)7@@@6=")="
@r2481
GGGNCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTC
+
+8=?+:G1DG##/99>&#F!AB49D>'8('BC?0@:)''@&0C'*761%&H#0@.
@r2482
TTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCNCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATCCGCCTGTCTC
+
8>B6'4)D).=C4E)22!#<B#FE.A-E>4?+*&%/,4%-H>)@1B!4C;<<0($@HB996B)D3E%B((52D,.2).2'#-.<@"H@A19*$>=BD)A)*.(G)&+58H3C@;)6.'7/3A9+6,:.G)2H4.(&)+
@r2483
GAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGTCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAANGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACNGNTCAGGCATTTGCTGCATTTA
+
?)E"94%+6053#;>"@<0H.@&8+F9:#("53+(=E.2E!FAC;3;93G/&B"466HB(B.%$H=<G9C-':C1:?E($<"E'-<-4;<1-8=4=>;2,8GEH,)D80)G+F1.,%GB.%2,B"(=*C?+FF"#799&E(2D35'@G09?8<68<0$1!F$<=ED:E;@+?+)#-:G95'G6A3,4.4?;D?=,?E,3G5(B63D>G=F:@?E$2*G)2,!'&'*D$9#/74440=;
@r2484
AAAAACAGCGGCNGCGGGCAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATAN
+
0?))-(H,'$9D2;0@:/>(9@>C;F.GE%)8AHG$%>A"6553H6HC4E,B31-&>",97FHF!'7)(=-'3"'G=F(2)*?$@G)D:8*14"D$3@8A).GD0<E<131E?"B="??H/B%H&#D7.!,G5B<,5F.A20@)B$.
@r2485
CGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGNTGCACATTAATTGCTAGCGAAAATGCAAGAG
+
:=?!5DH"C&"%F$.8(<:.%,66$3-D9F18.<67*!%=$:$>AH&(.(;7H,D4,2*!H6-&@635'C0.3"';2>6,#(>+%.3"9$(60G@(4H71&"G0A5<3-(B7
@r2486
TTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCNTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCGACCCTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACNCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGANGGGAATCCCAATGATTTGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGC
+
?(!90;,$'$G/E:0'86&EFA0/"+(*'(*%(FEEE)-!-2CE)/:&F1$,)6C40:#GCA4"-4:DCBHE0,5>;3+HG561=&"+9G7*)A$.=9=?6.FB$D!"7':.,;(1:%4G@C=!&+G7E)6H)'56"88D84*)AH6F%54@CH5B,/#7F32?:4$@?='C''F!/$G4@37&:7;,4&"?012$:4@!))F@8)$G+60-&@A6+)9A0-,DG!8F20?-#521<#?.,2)%1'C)()(;/>-;F@D%#;:G9/7"C4"A&(9"#%4,6D>":B()B8B&1,<-6E(':C4AH7(5'<D?C2<9@E?)B(9<6>'G&78!!2*E9@$9"$<D9$8#337ECFD(10+8;)3(DA?.;!+G"A9:<4C"/!9E#)$#!50EB-"#42%.0@2--:=.A57$2."<FH:EF7E27&27C4:@8D"8!16/'**)8#,H+$/4+,,$H"++)30<G'@A07;)20=$(69@'@A9D#:?9C
@r2487
GAAAGACGTGTTCCTGAAGCGCCTGACGGNCCCCACCATTNCCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGA
+
5H=/8.#ADB-?140:=:H?+4:.?H0<1/8=A@FHCE./H>9,H:$D7;1('$!<6'G/?@FGE:E!#89F)6
@r2488
AGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGG
+
C>/"GF(-5,(BB!3.6;"<G)*'/6C-!@>.#>(,"E0?F:E0+?)G5$3F-"($3F/F146E9EG>?;,3&$)43%.HE3%5#9E<,C7G!,$@0D5=
@r2489
AGCGTCCTCACATGTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACNAGCCCGNATC
+
F,5>,B&..5C44.*E*25/;"&@#2F!,1A&)"62;6:(??"28F02%#.AH(-!<)&*C%'D
@r2490
TCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGNTGTTAGCGCGACCTCCTGCCACCC
+
..2%)46;"-/>4@*!'(GE*#-*)4B-)H.<*>:2%?6.D=B#'&?9$2F21%$8/!#"?,2(,;>G@%)<91"=.D8CF154G1*96))/*:@0/%>':635??G5--27
@r2491
TGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAG
+
D2=C>@FH4GF<>E!.*5F@9;!B6>4,H>)0+!/H$1'#,>F+-
@r2492
CCCCCTNTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGNGTTCTAA
+
:0H8A"54::(;1CEFAB<*=>F;>B!',2(91</5.>#28HG44D?3HGB=).E9DGC.*62&''>:0<0H,F>,B)04:@,G$D5>51A&F)+B3/(3,'-G@'3500;@!$3"3(9%2-#&(&'H.1(H=<6-'$%>6B21%2:6;AB7>E=>(&2#"7//$B38
@r2493
AACGTAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGNC
+
8:;?3&*'(C693B,E/.:*3)8*H5*<$#FF270;'EE";EEF(F628?#2($("5#)?.0<#)*&<$,,?6
@r2494
TGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGT
+
3%G&@((!E8&>5"B;?,?3)D;8>/9=0.>693*/-#=@F;<+'-
@r2495
GCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGT
+
*4".?C7$D@$?",D&5.4.+A@!+82(/?$)E2GED)7%$"C<5
@r2496
GCTGTTTTTCCGGGACGTATCATGGGCCAACACCNGCACCTGGACCTATCGCGGTG
+
5,2@HD?867;F>6:2<1D16"?DG@@>6!1H=(-FG&3D(%):/E"7!F.D#G&&
@r2497
ATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTA
+
-,0:D)4#5E-"BC,%4B!E".6A&@0/D:".74A0.D56@&+9..C++=0E>3-
@r2498
GAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAA
+
6(D.9G-),27=:/=.#DH2"=,/>*7"G!@#:?,-,1@D:!92%9#:<#<3B8"E1;/";AD%642?4E7"41;2H!"8)%HAEH<=>F<9F%*+&/.D2'5D.&*%13$';=",$7'3&4/A/E;;=*6+9B/5;4"C+E;5!63
@r2499
GGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCA
+
<">BE*.1D,A$-E&*%+4E9-9(9'?A(E$9D73%,&,8>*@6'G$%,A#97F.G%+:/?50D(3/)B%"4F2$!8B&B4CB&%)E"3A!2.)/6!#""27*4%5!.<%2=5G&=H.%;.FB;5-&#72#F"C+8F8"":>0BD04,H)*@F'B>1/8455"??D-?(@"+:="FF!,=.A1B!>2.>$A>
@r2500
TTTCCACGGATAAGACTCCGCATCCGGATACACGCCTCGCTTCCG
+
E9@;+6=56$G:;7B1#A.%1<4/3+8/#(0=C:=B'"?HC>&;0
@r2501
AGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGAT
+
!+""%%#$'#**$&!%!"!'#*$#+!#(!$**!%**)%&+++!****&**'&)*#'**%)*+)")'
@r2502
GCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATCGTACGNTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGNGCGGGGA
+
''"++$!$$)!(*)#(%+&$"$$"*(+#*"&%&!#!%!&"!(*%!*(($"(*&$#"$&!!$&*$''$)&'%#!$'#)&*#'$&''((!'$+'&'#%""(#*$#%
@r2503
CTATCGTCACATTACTGANCGTCCCGGAGTTCGCATTCACACTGCCACGGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAG
+
32.=/<)&70,:8-(',"H.32@=;AC:%E)2<8<C=H+G#*9",*(?A;4D&7>!'#.&@3*H++7/!;3#1)F1$$:$6"D7$64-2<2;B*FD;)FCHF*>5G.*G567-C4?G.6*3>2.EG)C;8%<5=E+:*6
@r2504
CGGCNTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAGACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGC
+
>F+B,=+4B6-9B=E7#<GB20B.C7=C:>&G04,9A-A67B"78?*83&7<,'8A3.736,'2(@8/,6C&!$/;<10/-FAHE2.+3%,$C4$(:5:A5"761FE?F,?
@r2505
AGACTCCGCCGGAGGGATTTGAATCCNCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGA
+
HE!-'/3(0GF5FA338&E)F!H"$$$HB1<!H=A/'A<5&*;)G*$$CA@"E2<&/82)34%&AB5=6F7H6A6!C:G4>%@.++>C>@)>.E3#2,A//45>@?
@r2506
GTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTNCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCT
+
,";/%-,D#/G-E"(>.C91H#>A7/-#.?&8B;F,-&*,4.%<3-4?<5#EG%4,%@:>0<0705#..#5AH4*:
@r2507
CACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCTCCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCNGCGGTTGCGTTCCTGAATGGTTACNACGATTGGTTTGGTTGGGTCTG
+
@("B1G440G4:C2'DGF;=28B$&1B:<#;00C!*/2,#:48=.EC+E:>0<1C@4D'$():<03A/$C#120#9.0<6=.,6C-<4+)@9"!#*-&,9.8A:()!.&=F-C+<FEEG$/'A@+?2/<EB;";>'2?0%1%&=?@:
@r2508
TAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGG
+
92@4,>G'%C(8717EF?-4'24?CH#.5-?/CF+9E136(;#;#@HF
@r2509
TTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTC
+
.)=/H2)FH)6*3>/($=,EG9*B$DB)0G(B/*8,;//=&H#$>?>/%B%<CB,'>9<-!(E!(E7#%-45'A<G;+(=2;0<;1F41C:2/?>"2.4.$"0*
@r2510
GNGGAAGGCGGAGAGTCAGTTCGTGGTGCTGGAGGAGGCGGCGCAACGTCGCC
+
($+E==800<(G>+/-CAD5&*@-4'(=7/C5<G+<.45!!'%4C8&3",/!1
@r2511
CANNCNTAGTCTNNCTTTCTGTACTGTTGCCACCCGTTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGG
+
&'#)(&&"''##"+!*&$()%#(('*%'+("*+*+#&&))'(*")+$&(%+')!#*'(#+"'$##"!*($&*))$)!+
@r2512
AAACGAATNCTGCATCGACACAACANTCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCNGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTNTGCCGCGGC
+
17$*7"7?DB+:*685>9%=,"3%5H%7HF%(EHH<=B@)F@.D;C#;'@B7FA>7@37EA;)=B<2&6%H"",G;()&$#/43"='98)2>:1958=4A3CE&#EF+!.BC=1D"FCD2-'>&@=&<D'F,;;C9G;H>0CG$24?D(.1>:@/'>C0B!C'#2%(DC3-*FC<=,<*/HG6&D@3/<?.F;/*,@GF.@6#5149C&-<7F+D>3E0'2$B9<EF<7&3%<,B@C5;C.9@G:57",3A5->%668:-8?#@C
@r2513
NGGTGTNTNNAANANGANCTGTTAGTAANGATCGACATCATTACGCATNGCTATNACGGGGNTGGAGGTCAATGGGTTCAGGATGCAGGTNAGTATCTGCATATGATGGCTGACGCTGGCATTCGCATCAAAGGAGAG
+
*"#%"$"(!)')%)!*($'%(()*)(%%!"!+#$'')&"%*''+$!""(+)#&)&##&+$**#!$!+**%))+$*!%!+%)'%#+)$*(*"!!&&(%&*%**'($'+!*#&("$)'"$&+%((+('!*'!))!(+%**
@r2514
TNANGGTTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGG
+
%%%%(&#+%))#))$&$&"$!)$#("&+&*!+*))$*$&)##+'*#$!+*+&&+'!+*)***'##)('))&"(%'$%&(%*'*"'
@r2515
AATAATCAGAACACGTCGGCTCCTGATTAGTNACGAGCGACATAGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTG
+
C""35&@D/HHF3"'6F?*H*D4;D6"G;D<<5&'99?H@A*<$$5HG-&C0A@C*>.E'#6+7+E++#B**1$,7<=57=F6.4
@r2516
TTATTACATGCCTTAGCTATANTCTATGNCAGAATGTANAACTGCTGTAACTCTCTTGGCANCGATCGCCCGCAGACACCTTCA
+
;=>?/H(:)*921E6E#B6G&>A9<(-D5:>D;3-0(4)"F:;A#4A<+,E;-?"/A8)547%BH9C@F23+=8BG#@3(6F+/
@r2517
CGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTC
+
A)%++;!>:2@&1!$F/%')C6):4/.+$<?;,-28!3!%HC0D<A
@r2518
ATGCANTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGNTCGTGCAAA
+
6>2242/>#<68C;.'(!!-/824,D%@,HA@H:5.2%0#:-;35)H#*B3&D$*0@A%AB>'E3%3
@r2519
CCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAG
+
)B?5/BB)3A%>";>2C$%'4.#<)5F700!4+*A76B5./EA-:%)E5?D-"::*,):%.)35C-6/<<CC?',D(F/!E
@r2520
TGGNGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCA
+
)%&!(=E)$-A1(7$6/;;,EE"43;*B=6A-:>!>.9D8#:5,3&15*G67/$H@F
@r2521
GATGGTGTCNCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAANATCTTCANCTGAAGCTTTAGAGGGATTTATCTTCTGAAT
+
%"+&"#%+("*+$'&*+**'!)(+!%)(+%$'$"&"$%#&$!##))"*+)'!%!++%$+#+&"#'!%(*$$!*)"%"$("#!)!"&+%)"'&"')*($'*+%!'*$)$+*+
@r2522
CATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACA
+
G33/5>9%(*(9HH$4)C*)94'0HF3>"GA:791H9!'F9+</2,/*B=H,C)=7%BG@&
@r2523
CGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTG
+
<(<6#'#$@'-E0D'>6B4F?090'409C40@,/>68C$>+C+GHB19!3%(&9;43%#B9)6@,28:B3B4C")>D-$C"4F,+><
@r2524
CAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACATAAGAAATTACCTTCATATTTAA
+
&-%6G9$@!;=G%(06*$5:)%"?=D89C@:<"7933B1E=E@/"%>9-/48-:<D=FA61676$'ED"6E)0*<84+;!2@/2=.5E-&='7G(D*=,?3A2A/+?G9!7D**:+3$9&>1C17-74-
@r2525
GTCAAAATTGAGCAGACCAAAGACGGCANACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACTCGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCNGGCAAACGGGAATGAAACGCCGATG
+
;%)*%BB6')+D:D>&*>=.E47+!//3,"8/FB&+E;',$H21@F7**+DC<=+<<!C)'@A)>D:/E/"07-B&517G"=)27BG?/"B.GA(D)4>!E=%D1FB-@=//B=2&FH0<3B./87.6G2'@-@6:;2E$+>7<4;'-)2&53
@r2526
TGGNTCATACNTNNNNNTGAANNGAANTTTGTTGCTTNNNTNNCNNGCGTANCTNGAGNACCTNNGAGGGGGGTCNATGTCNNANNNNAANNTNNNCAGNNNNNCCGNNGNNNCNNANNGGTCAGNNTTGCGCANGCNNGNNAANNGNCCANTNNNNNTNTCNAANNNTNACNGCNTCTAAGNCNTNNANNATGNNACGNNTANCTNTGTTGTNNANCNACATNCNAANCNNTNNGNNGCGNGNANANNCNGCNNNGCNCATNATCANGNNCANGNANNNNNNNANTNAACNNNAGNNGANNTNNCTNNNANNG
+
$$$!"#""#!!$!"!!!"$$""#"!!"#$""$!"#!$!""!"#""!"##"!#$##!$"$!#"##$#!$$!####!"!"#"!"!#!#"!##"$"!!!"#"""$!#$###$!$$#$"!"!$"!$!!#"!!"#!!!""##!$$#!"$"!#"!###$$"#!!$!!$!#$$$"##!!##!"!!$"$!!##$"!#!"#$$!!#"""""""$$$#!$##"!#!#"#$!#$##$!$##$!!""$#"#$"$"!#$!#$""!"$!#$$#"$"!$#!"!$!!""$!""#####!#"$#$##$!""!!!"$""!$!#"$!""##$$
@r2527
NNNCNTNNGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGNCAGGTAGGTCCGGCTGCTCTGNAG
+
"##)""()*'+'&!++&+#&&*$"#"$#)#%*&$#))")$+*$+#&&+!&")$*#&#"*))&)%#$%&&'(+"'"+)'))($'**#
@r2528
NGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGG
+
"<<*<7)7?$6$B//+7*B:%913*-+-#$;+?;)#8.F,5-1A6C'??C;"!77(AD!:H-*,H=@9
@r2529
CCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACAATGCTGA
+
66B(>ECG+28A(A>218!3>"*33/31GG./9;$+=A)BH><"D(&!,*1*6!$F*<8
@r2530
CTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGATGTCTTTTTCTATCT
+
%E&;)/#:+#8'55?%E&9(84H:*!3G9F-4?*!;@@B'@=065.$9B6(#"E3/8-?4G9,+C,D(?:F45=0--C<2
@r2531
GTTATTTTAATAANATTAAGGGTTACTCTATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCNTT
+
5(H6A'?@H3DB1720C@@('!D:A85>#63C17G<$'":+06%.#6G2=2!'4+)@>5%CGC(CC&*E2"0:!D"!$&@E3?$"A/F7;/D820'/CC/*B/H./7!775'01C,;:F8+7.)GB*%
@r2532
TTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTA
+
H*<;0H/F'0<DB.;.68,/,53<)DA+))+F$A8$CH2B"31F+B,CAGG8G4
@r2533
AATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGNTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTC
+
25(06)+2*;%7+8$:.6B$3"@-ED:22:F!27&>!H3:H9=@A0)$6@3*;%!'1>0*@7<=<>DFE>-7&63D+)@:.+@5&$:(C9:88;)5!1*H4B66C,E''ABB<:&1%<5A'EA9<!E5,CH?9*<)/8%BF<#/1E4/FECEE-*60G6+?9?!(-(,C:F%)4!'@3#$:9C4GD48*,;+(93D*=B,!+.2&4)88G=>4//19A1&D)3*9@"0"(A+B
@r2534
AAAGGCAGGTGGGCAANGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCA
+
(8;6%G:G7E443;33$"3"0:A.!/%%::@:=H'>BA&E5)D:@1D=B3";DFB+$=>2
@r2535
ACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTNACTCGATTGGTNCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGTGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACNTCATTGTAGGCGGAGANCTATTT
+
;*9(H/.8=7&?:.7B;.B,&0*$$8":5.EF=D5;%+)(!(E-9<,5E(C1%(?BFA.D/$-D,G6.F2A3*13B5*FA@,1FF$#0?196&.'63B9-5."1D(A&@,6-,FG:0H<%)752")+&7-855("H-;%&2+&&6)<D#$.@+8*)0&,2!9@-%*#+<+.EC14>-B%$BC15EE2"<>?H.-%36.E*"1/9EAH==:5942@(10F87(2F='533+$#.=>3/7H=D=B1!H
@r2536
GCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATCAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGAC
+
:077*0?)4'>(H<!9EC>C!<%A;'%/#2C+37@9.;21<!;F",4&E7"<&?B=2H):9$E=+,(B!2D7!.,6GH>?5(&$F?"(4/<1;-
@r2537
AGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGC
+
2@/-:=;=$A:2A-4'66?DE18:#8!$8FG3,3#(&:8#..(0;2+D+?D@&(/)AGBF3>F
@r2538
TCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGNCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCAC
+
9#A@6=;%7:3-$2-%A/,@&!2(A.90-9"("4(*"B.-6<5,(GG-2H%//9.:/-%E$5)%!%B+"58*>DGB*<('"314-&2H<F7
@r2539
ACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTC
+
)>04(;4=4B-1/$*03G-47D)!-,2)EDG>/6G!CA<!C+.5H:G,!+-"80H(0&$>=>":
@r2540
ACGGTATCGATATACATTTGGTTGGCAAAATTGAGTGGTTTCACTGCTGGCGTATGACCAAAGCTGAACGTGTCCGCGCCTTTGATTTCTTT
+
#*+)*'!)())!%#*&+"&*(#*%()!(%%#%'&*+*&&"#)($##*+"#((#$+%$()+$%'#''+$")!*$')*'#"!('*$*+#(((*$
@r2541
NANCTNAATCNTTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATTGCTGCATTCTGCGGTAAGCACTAACTCAGCCAGAACGACAAA
+
#$'*($*!**!#)**%+)")$%"+#*)&+**"$*(&!(+%'(+&%&**$(%%$&((*+%+')!%&+$)++#**((*+%*#*'#"(!!+%*!)')%&('$(*)*"(%*'(%(#+&%+
@r2542
GCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAGAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGC
+
969)>:83&,*#!.G0:!@1D64+F$/*;*-F-2,2'*6=!&$&D!(6!:"*#C90'5*:='0.C#@?3.<:+:68"8F"1/$9/!-C!G0+
@r2543
CTGGCGATCAAAAGGATGNTCATCGGTCACGGTGACAGTACGGGTACCT
+
E9D;BHH13:7-#@8!+00557?AE-D(.E(CD7%#981!E6+#FB#9.
@r2544
TCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACCGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGA
+
B90-H?!.@C8-#F'8&4:(+369AA%3#*/@#*0:5;,!--CD,?*/!5G=4HFB.0,F<GA8,@;?>%50$H3#0+;'('C"9+=6/!,7!,A'?'"!F.C)?))'C.#G'4:7,4/;"!.5:@)+!?H@:3?>CF-:@+62@':=D.190AA&C?C-"*:0)<2<0GE=92B26.)0887=+3?,*-':$6&GD=#2=<G;/*'?>".$&$<=!H:<@#74D#()!/3A2&>.47CC)&66E6;:#H#F&>&@4)FG;:5-<14;=6
@r2545
CAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATT
+
)6F.-4/&EH*7-%@5&)$@.1FF:3($=6$-"#)5*/H4;">B'A-G,8/G4$C"1&%080D<3#G;/?C/C24
@r2546
ACAACATGCCGGAGCAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGNCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCG
+
94A/@<48B-A>AE%.B,@#B%)-4?(6CG6)-9>G?=)F@-/%29GB.+"8#=)>-(+?0@&5-1H/+12$GGB:*115%'&D>*&7:6D+@A>$D-E-4,3$&8"?D--5!@%30D(#151(:GE87D>"CGE(;B926G
@r2547
TGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCA
+
'+$+'+%%!(&'(+$#$!&&('#'##&&)++%)"*+%"()&&+'""
@r2548
AAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCCACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGNAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATCCCCNGACCCTTTTTGC
+
H,+<#=""E@?D%1B"(/CE@D0$0)C0H1(%<'-<&:9#5(G?@/E,9507DE&1/=@;86333A#:3,B63$+B.5,+#FE*"@-*?+A6FDG1(31E;<?,!-@2A$!4#H1/6)?+;=F"5H+DH.>$H=F>2(15*30D7*<H%!67.!78<+@>!H0AE#?=$5692>+<./A.8E@&B69*;1ED40C(FAC2F>7#&6)<$",6@=7'?<:.<8-!BE&%>;46.@@:8"H;=:4/'EE,"12H/6<:/E:,29=0,CC<0)>H*(*G?/+8?-=*#A8<@''&/)<)A&:=#'9:+)5?":B80)!A;AE<("=0C<=>F3<&;D(,>:).?2.F8:!8/@0*':+
@r2549
TNNGCCACCCTGCAATGGCATATTGCNTGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACC
+
$)$(G%,A)!7ED/&1C.%'16>-1FH%=2!%'44;E"@*#(*3/$="7=;9,,/=%)/17E8D#!"",0!/<=?.%1'7FFH&--=D"=@('6>)=4=D7;G@)5%*180@CE:5'8?'*1=%3F>')03!(%A%:A#A:6**#4<=:%/@8DF*8(#>0H@5G/8%(H(=)C4*A?&+A
@r2550
CATCACGCATCTGTGTCTGAATTTCATCACGGGCACCNTTGCGGGCCATGTCATACAC
+
6'",!EE??72*0H.G$#G@1G1DA.!A.,&-CD5"<69<*#4D24H5@FCA4/?!FC
@r2551
CGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCA
+
H@1+=!*(#(/HA%3?H%3;=&@E=3&C(46(?H6C08/?0#--42&9+;G32=8A'80E32G@5+&,;<$
@r2552
GGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACNTAGTGGAGCAAGCGTGACAAGTCCA
+
1%'%-E3:<3:AC:;39G&#6B:C94,4:!*.:$#)#(9)&/:*H>B643!>F+5%;;>!8H850/?4
@r2553
GTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTA
+
/?/:F,#8"$6F8'G0:G8A"E-?&=F&>-C43?31&*-!B92?3-6*C*/0F879F@<8'>,0>B6.
@r2554
CAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGA
+
H!8>"9-C"<.((?7H8&95)+3A('F1)')9B8+=6-"77$50,9*-
@r2555
CCGGTGTCAGGGAAAAGGCNGGAGGATTGCCGCCGCTGGNAATGGTGGGGGCCGTCAGGCGCTNCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCT
+
)(@;(/00F*5)/'01&B)H:":052C3+21'-48&C5-?(+"3$,>HA520#H4C7+4A(!,-..CA@8@G:;@7@.362548/=0+D9;7;=GB&>AG@.6"@B;=$)>6D"$,'"@E!8<#5-?A6+4?/;3B(>0%)'1?E;D&;A7B8'4%8>:>B)=E"$%C,H*?E.:5!?
@r2556
TCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCNCCCACTGAGATAAACAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAAC
+
<&9:9"#7?*@3E!('?2:4%D&HAA814F&11FB@/#/..1?/FE;=<#,!"E'A=D$3)!;-<4??B!D6E<*5@"CD.4*:7")H57)*B@:39<575"0;*.'/F6+C8(?'FC"G.;-E@(;=8<55!"0@+'%'"$("*?#D9H=8-@F@!=9>"7=31>+"=58
@r2557
AACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCNGANA
+
56AD/#*"=">655!1"!''H!D))>74E=3C3B8#64C.3H4+*)90<:561D)+17?
@r2558
NCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCANCATATCCCACAGACACCAGGCCATGTTGTTGCNGTATGCCGGTCTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTCCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAAT
+
"&""+%'')*%)#(")))'"&&&)('(*+$')"''))&#(%#%+%*+))(+(%$("!)%"%&(#*('$'**&*!''")"+'#($("%!$+)($#+%%!#&&(#"++'#+!+#("#)*$'(&($#+&'&$(%'%+'("!$"&))!(()++(*'!%+(""')'%!&&)&$$')+#!**$'))
@r2559
GANGAAATCGNGNANACNANNTNGANNNATNNGNNNNACNNTATNANNNNATTNNNNNNNNNGNCNNNNCCCGTCANGNTTANTTNNCGTNTNACNNTGNNNCNAGNNN
+
#"!""!$$"!!#"###$!#$#$#$#$"!#!#"$!!#"!#!"!"$$$$#!#!""#$!!"###$$!#"!#"###$#"!""$$!##"#"#!""!#""#$$#"#!"$$#"##$
@r2560
GAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTG
+
&C%:&6)2D/(;62?&9;>"(-!<H06CH'A&5)G@C4G#'F+*B6(5DDC4.
@r2561
GCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATC
+
>.&'=6(1G??$/FA@147FE'>8;E#2;:#*F<0359:.H?6=:B/
@r2562
AGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAANCTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACA
+
=!</78B)(7$7H71((FD/.A%'"BD7F#!@1EG<B"2%7'9:C*/!15;50.=E&3G'CB,>4B&4%<':.</#A&;1)$GG#64BA6.076@=F">>C=?2$B/$4.4+'-564$6>4E+C;
@r2563
NTNNAAAGCAACGAAGTCCGTGAAGACGGAAACCNGTTTCTTGTTGTTCGNCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGNANAGTTTCTGCGGCAGTTANTC
+
"$*!*+"!"(&)&)!'"+'!+&)&"'"''#++'&$&+&!$'*&'++)!+%#&($!"#*+$*"!$+%)%*'*%)''$#+&#+%!)$$&('%"%$"*+$&&(!($'%&(**'+*'$+$&!!
@r2564
NACGGCGGGTTTTGTTTTATGGAGATGATAAATCCACTTCCGAGNCAGAA
+
)7+D>0CA=&G,3.#%.%3'*%/*2=<0D6G"7).1A(3H#"+%,!)0:;
@r2565
CANTGAGTCGATAATCGTGAAGAGTCGGCGAGCCNGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGNCATNGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCNTTAGTAATAGTTACGCTGCGGCCTTTTACACANGACCTTCGTGAAAGCGGGTG
+
)+$()&#$(&&%!)!+)(+*'+#$(!(+&!'$*&#$#)('&+$"#(!&$%$'#"!&&*("'!'%)#!%('+'(")'%'#+#++%"&!"'&'!%'"'&*$*$!&"$'%+%$(#"#'*')$!+*"&*&&'#'+'*&!)%*#+"!)"+$!*#!&)"*&#$"#"%#$+*)%$)%$!!"+%'##('#%$%)(+!&&)!#$'%&$%%&++!"()(+$!"(+((*#*'!""")"$!#
@r2566
GATAGNANNGCGTGAAGGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCG
+
))&"(!'!"!&&"((#+*(!!&!*""#""&'%("$+++')')!(++)"((("&!$&+%("##+%&&+"!##''!&*$)")%&+"('"&'(*%%+)&"*("$'+*'&"#'))"($
@r2567
GTGCGCCATTATNGCCTGGTTCATTCGTGACCTTCTCGGCTTCGT
+
>;?/'D&/4$H=##=?((,!C>BH/B/AH'&?6E#71>(8=<+63
@r2568
AAATGTTCTATATTTTTTGTCTGTCCTATATCAACACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATT
+
?GF+1*$-@1(-&+G.907.(/8?,7HBB,'/"G"!*$34+9&#"-'3%"@!EG+=B<3F7>-&H!5)(D15$8+.'H%A8&H5/8!"*B;/1.>'(5366*B6)!'4;+)=/>@3F&)
@r2569
CCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCC
+
4-C.>0C&0=(GADB054<5("#A>3+91>!"C08'>:)@"F<(*0:?!,H+B(/,G/G"<D*(5)=?@",>%@-C<>!43>98<*H3/FG
@r2570
AATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCCTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAG
+
89@7E$*1GB77E?H3()6(A6;'?!DHEDD.E!=>9*A2A7;'$9=)#*!@GF$6;0!/+-H3#$F8**8G@9;?D7();07'9<+"=B78)!/%80B"$(:))A(6&A!*BBCE:.9%!/D*/=69/?F"0'"=14#$%<+:/($CA:(*>-G8!.E5A(-FD1?>F.D44'E(@%<=C
@r2571
TGGCGGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCG
+
/&6E/!!G%6A.EE-==-B3E4>9<,F$A>/?+)33FH."
@r2572
AAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGNCATACCGGACTCCTCCTGCGATCCCNTCTGATACTGTCATCAGCATTACGTCATCCTC
+
F1C"%<F%:=GAE5?;24#%=24<86,D:B=A8(',&2=)#4$D;4<&/;!.2<FA8=#:G"*C.&-H3G@F<0$:B"E:-5!B7%("@1:!,"$B9?)?;#C4;)4#D+E3089").$%!3);*6*$$<7F;+80%"4!(CCFE
@r2573
ACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATT
+
!<52$F,-AD>&D-?!'#D7?"$-,CA%F$8"!88D@)?G
@r2574
CGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTNGCTGATGCGCTTCGGGCTGNCCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACG
+
&-#E4)+.-">'0!C>&"-%-1F/F/=';B?:"@15E?1)-47)H*F/'+5:!),047.?C82D%!E;((0*$8F6"&6B82?&F/2+7E'@?='G:?.3E;:/='%+G4&-1H5C%!"1/.E41+&%A2%H6F!-*16>*.D2B5G>
@r2575
NTTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGAN
+
)"*+#+%%&$"%(!)(#+$$&%&(""*+++$(*&''#""#+$"#!#'
@r2576
CTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTT
+
5(B!!DA@8,%;?9#C#6FF@.&(3C;36.E!5?><AA4#
@r2577
ANNNNNTCNNGGCGTNCGTNNNNNCANTNCNNACCANNGNAATNGANGACTGNNTATTTCNCCNGNTNTNNNCCGCACAGCNGAGNNGNNGNNCNNNGGNGNTGGTTNNTTNCNCNNGNTTCNNCCCGANNGNCCNN
+
"""!!"#$#$!"$#"##"#""#"!!$"$!!"#!$#$$$!!$!$#$!"""!!"#!""##!"$#""$$$#$""#!!$"$$""!!##"$!$!$!##"##"$"!!#$!#"#$!"$#$""###!!!$##$#$$$!!#!#!"!
@r2578
TATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTA
+
8%)C0(#8?16A+!!"EE'6G-1!?9)2=(;645)6/E:#G#D#,A>5.#E>+976'(/!'/)FB.(<0*/(!"-3374@*&(##.F,3.)(3@7&AGA8E7!&B.$1E:!!60<B9%,#!:3$*F)67G@D/#53423@1/FGF@<$A4C';$3C*3&*'*@A'589,B**.,G5<&."5@39>?4;/8)6,@4<8"503&G2-G*A#
@r2579
TGGCAGNTTACNCCCGTGCCTTATCCGGAGAGGATGAATGACGCG
+
===5C"?@/1B0CH+(?E?,3#"C=@%.6!>03$"::%G@31=+&
@r2580
TCGNCGTTTCTGTCTTTGCCGCACTTGCNGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTN
+
(!)#''+"&$)#)!$%$)+$$%!'(&&$%"&++!&("&(%&(*$#&*!+"(%+#+))#"'%*%#+('!)#)!)#$!*%%!
@r2581
GAAANCTCGGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACNCTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTNTGACGAGCAAAGAAACCTTT
+
))*"'*"*!+#("&)++*&++$(%)&$$%!%('))$#)++*"+'"#&%*(!%)!"&+%'*(&%+*'!&)*$+(*+%&&!$%&++#"&+(!%*&&&'*!+!&'%*)*")#)&)"%+#%%(&#("*%!""#&#)%"$"($!'+"'&')+%$($)&"&!$!"$(%)+&('$+('('())%$"%''"#)+%+'")&&&")+()#'%"'")%
@r2582
TCGCACTTACGGCCNATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCNCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATG
+
%FG.71!-DA7A"6G1#@H5!G:(94G%972@C'-0F6?"':>3$1:""DHD*@-@!41?4,C::%C31?.(7A::33G+01:@:>,BH=#.%-H6F)D>&3.4"F=*(0*A887$<39-@C4H2(=6
@r2583
NCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTACTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTTATAAACTCAATGTCATT
+
#=:=,2$3#3,92)+0".DD?01H!H>>/GA9$F3E%@-/B!G#'*+="?>"2#1@#7=+5:E,,.(**>80#&-4#E+'+(24D,A*DG0B,+?A,/D!9'-HC&3:5=<52A$84+'
@r2584
GCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGA
+
;>1>A!).:6(,*3?*"!B:*D928'C='FE#1.E/D.&+:F>HF50+9F?'D-%A@9!#1(0E1$->
@r2585
NAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCA
+
"<)'H=41C>>4H&D2D=D;'#>HDD<2##7-<D!(>7F/
@r2586
TTCTTTGCTCGTCATAAACATCGCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGNGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCNCTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGNATGCGGCGGGCCGTTATCACGNTCATANCG
+
&6@7=G62/4->6&,>7G.F'8AE,-A!$H%*!=0+;$:/.>1H3*E;9B*H.?>=/HAA"EB;>D29FC/E9G5GB7..'9#ACC8C<,'"+43D<'27+/@),8>CG$!5-ED"1HA6H"H46;=G%7?B@.CD!1632)B3$:*=?1?$$%;@<';+@/8)</175.9A+?/*9.%9?0$D$>%)63.='
@r2587
ACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGA
+
9.",9"9B(*DD)9.A#'&BB+1#$)?6*),#/:6'"$'#40.""E/'+?
@r2588
NCGNTGNNAAGAGNAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGNGCGCCTGCCGGGCCGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTANTGGAGTCG
+
!))%)($"'$#"#"(+$"(+!+$"('($'*+)(*+)')&'%(%+*&""!((#'""&)(*&$%%($%))$+"##"$(%($&%")!$("$#%$'+%)&&+)$'''%()()&*"%+*(&*$(&"!)"$+!&(#!!'%"+!&&'+*((!"!"'+#(&!')%")!)$!!+#)'*
@r2589
GATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTAGGGTNTATGCATTTATTTGCATACATTCAATCAATT
+
E+DE&B.0=;G<!1E(3;0.<"@(A=?=;"&>"+.@&$&.B/%7:F7(09;$?,CH+6).G"B"1)17.:8#A3/7"2G@(@(!#*<2)D#&)C%(/%,6A?+09!56#17>$G<G#!(<0=-)!55-/>A:36"7<BB#*??=EEECH,;&B6>2'?
@r2590
CAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATNGCCGCCGTTCGTATTGCCCATTTATCGACA
+
DC5.A>7C6B>$$"%9.=B32F%'8'9!G$9"5A$%+$D*'E/A5/:&*A%"9,;/=13+D?!?509E&F0;BC1
@r2591
CTNACNGATGCTGCCATTNCCCGCGCCGANGAAACGATCCGCGGGTACATGGGAACGTCAGCCACCATT
+
)$"!!#+'*"!)(!!$%%+*"*$*!$+%+*'$*%#'##(%%$%%&)((#$)$!))($%!%&$%&#"*$#
@r2592
CANCCCAACAGCATTGCATAGTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAANGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTAT
+
'/*4!.GA,&C?H4-.<?:B?6$2DC&5?&080?&)B6'--&(./68)C$?10423'1!>?<E879=A;$?71D$*)E$*A+-+?F6%D)@!<G#4)-?70F?:7('.B#:0>5;F(/<D!+$:C6#1.3*E(9
@r2593
CNCCCNCGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCNAGCAAAAGCATTCACTAACCCCCTTTCCTGT
+
*%**"!&$&(+!$'&""+%*#)*#%"('(!#$"*"*+"&$!&'*"*%$&&+*'+&'+!#(*#"*""'%!&+(%%'%+
@r2594
ACTAACCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCA
+
,E2#H'F61%4@?*9>'B3@/H!3'!1F;G!>7&G!);1A?G$C1?FC3D,>?-
@r2595
ACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATNGGA
+
6F')#>!?+5"5/6,.H-<0)!55DG"C(7,B6EH?>0;/.(F217>03;)+"6,"$)BG(+>
@r2596
GCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCG
+
@6%H2.14F!?0!<1+325-C.-,=65?0541+!;)5<D&(+#2F;A7>
@r2597
AACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAANCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTAGCCGGTTTCACTTGAAAATAGNCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCG
+
++4$>E/16>);%6!/>%D>#B9E!21C'#H7E'.-%6>,7B--A9D3@9<?<.G%)!-(/C&G7@-/=?295(F?A27"521F&9A46G!E85-/:/,">(CD:*H8)A%G/#-+>@%#0A)<1/0@9'6%)@+8406D7),(.21,!!77)18H!%!!)(+G+D**096-*CB5.E%@E)-F!;%!/H
@r2598
AGCTCTGCTGNCACTCTTCTCCTCCTCTGTTGATNGTCGCAGCCCGGATTC
+
;H<3@14:(.DA;'*==%65""2B*7),&"2+4&$91&-6">,$8E-"/5&
@r2599
CGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCT
+
>+D*/61CC&G1(39@>G08;8(.60.;9>=&=748(A<.CH%$F@A..((%,1)=?.A0C%,?)':="GCD@25F&#"
@r2600
AACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATT
+
<E/D6=,'E/&,<5-3#C!&C9H>!4">8A+6+H!474E&37E=A><>>;'?E>@:74CG,D$G3!7&;3F:.#:44E1<GH7=/##6:A<(-"07D*.7.11=)?',$F%?HF#C4(G<F60+1G%'='5
@r2601
TTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAANACAACCGACAGATGTATGTAAGGCCA
+
339%($;9#3=436B9C#2*::$)D<.<%D+<9H/FA:C9.,4E=/8*4C,B;?.7>B'*6:%)F?%96
@r2602
ATGACACCTCAGCAGGAAAACGCCNTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAANCGTCGATGACATTTGCCGTAGCGTA
+
F?/."9D/&E5HF@?&(F86%8E&$*D4F</E";18H*%A!;AF5'5(?E-4()."?,5'8DB&!H6:?;:;+?'0.+7063=')5*G=7,7&<G/9>=:,/,A)",&%&27*A'11G
@r2603
NAAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCAACTGTGTCTGAATTTCAT
+
'#+))*#*("&&(%%!(()&%+''""&*))$)&*!+!*&+)%##""(%&!$#)*'*$$)&''$#$&$%!"#)%')&%$)&&&!#)&'$"&(%)"+(+%!$
@r2604
NGNATTCACGCANTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCNTACTGTCTTTGATG
+
)*!*"&&$!"&%%+)')!%'*%*)#")#&&)&%&$&*+!$+#'*!$+"$+*$&&''%('$#("'"#&%%)%&$*)"+)$))&!'+"%*$')!((%+#
@r2605
ACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAAC
+
D=D-'!;?3$<-1;C',?/3'7FHG>*A48,D/>43"%#9331=:*0$::C?5/-F)>F@%&C?%'@>0EA$G:<4C#//(=4@?'G
@r2606
NTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAANGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACA
+
1@&#43A+&<8E%,?*.HF1E:F&/5.1=F4-=8B'6)9'865+@F:?D-G->4#G<=*-'$.4F<>6&,.H$$%?8.;&C$AH,C&%D70H%383-310(/H0$5G:G9,@6%B<5+)?80/(6(.3A8;4$F:$5E<1-7,:3567/*;-%32%>+'@6!>F=B#D#>)C7A".0&>!93'"+<D&9;#"G'G-:B66
@r2607
GTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTNTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGAC
+
<-9B%&&%H,$4"</(.7C>5"57G7?!&'!)8D-$;GB-%E($>26.1805A=*,3%#:F'@:G:<?A;""?:+#!<1G$8/.*5(70"G8/BF!*0--=62,;7'@-;C"D'-"2:DG++<$@G4AAD$,:C#??6,=C
@r2608
AAGCATGAATGTTCGTGCTGGGCATAGAANTAACCGTCACCTCAANAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGA
+
+531";>!)@6>,7<*5>6EA(2)17;E!("/9@FD3C+(%;:7/?8B&%9;<H<+@+?73&7!3ABB><*G+E/31+!*CA@=CG(1961CGH
@r2609
ATGGCTCACAGTAATTACGGTGCTGCGCTGGAGNAACAGGGTGTGGAAATCACGCTGAT
+
3'@#*C:G?)#=9+F=$$8A?F?>9=4.059A%;+'3.HAEA,<.A=?H?24?>$$G2*
@r2610
TTATCGNCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTAGATC
+
-@D)1D:=*5*&$C:A&DE1A+3%$D@'=1::3<F*'6-(1B*A90&1-6-&.",*F?D+H6262C@4G:
@r2611
ACACAACTCTGCTNGNAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGAC
+
&)')$#%'()()%!)++)$$#'(#$&'*#+$+%#(&$*""%+")!"*&&$(#(**"!*)"$%)!&)$'"#&#$(!#($)!!$+"%%!)%+#)"%&*"(
@r2612
AGCCAAGGCCAATATCTAAGTAACTNGATAAGAGGACTCGATTTTCCCTTAATTTTCTGGC
+
$(@CB/;.60$=5/;:,CH?=+$%40(F!2!*0'$58F#9E@C/G66072=++./<E.+&*
@r2613
TCACAACGTCTCACATTATATTTACTATCTAGNCACAGATAATATTCACATCGTGTTAGAAAACGATAACACNGTGTTAATAAAAGGACTTAA
+
;$4>,F=4"A$@+:#GG=@G@G%&;7=1!0H'.&,,A(:24<<;23%'+2'1@-?;G1H/@?C"E:!#2;?('2&,);+%-5CE0($78"H#0
@r2614
GTGCATATCAAGCAGAACATCATGAAAATAANGGGTACTGTAAANGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCNCATCTCACGC
+
E$,/E%F-;:?<E'(:>:9%'0#(<?;EFF0>';;9+$F,@56(5+3(?:7+6&B4G#,F%'+=8*1,-9:5:2"&701$A"E-"1$DC*1#7'&"+!-/%1B?=!'19+&>*=E+C:59E
@r2615
GTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATC
+
"4)BC95E21"0+*/9&D%)D420E'87G-!D3:)16.1D>B,E$6D$<A;:D58,<C+D0G5?B1?/G8C6/,"1@9AHHF(5B.A1&B3;*5C)3F/2,9"4#""7)!2-G!#'E;@3?901"!F+D%77A+15<7@'?.A<43!E<H:!;8F>)$
@r2616
GCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTNTCATGTTCGTCGTTCCTTA
+
*?G;>>!4F%B(+)4,*E-><49&0>8"9)8'@,*G3<G=AG&29=2;!-2:E1=>H)H-:&7,(!G'0!4$07#D05C
@r2617
CGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATANTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCA
+
51D'F2F+2E20365<1/$<9""?0*DC86590+*A33>&D':D&D-"';(+ED&HDC<07-4AB!8)(2B1A*A*AC*H@9?H:@%E?--3%+A
@r2618
CATCTTAAATTGCGGATTGCGGNAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGNGTACCCCTACAG
+
;5H*..&:)B=H+H?=/A-#A,=3H2#;@':B51G%<#GH?"4H'57!C67>C)+1";<(,/BF4/*>G'%/%;64@989)C3!B
@r2619
CTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGC
+
E20723?7$25/*A+&-D:(,)%(*0,:)>5+?,:D0?#7??9),7'&H4
@r2620
GAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGATTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAAT
+
<<C./B,4)E&#=71138-%62)A$H44"!HC$-D(81<9?EHC'",C15:5;,67*"H*)$;8H.&4?C(#.?AC6#
@r2621
AGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGC
+
D(..H'7>F+2@!:@)$AD&$+C#)G%#+;62<>FF#./$<#15.>G'?4(#4D9*?3,$&B:@@-.0+D01#.
@r2622
GCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGNAGCGAC
+
CFB09FE1:!($@!,<G7!;CF;=(42%H5!$,258:$$951!D:>58B/G@/.)1AD7B-G('/>EA*H0DB"B&=0"7A(B%.F1+C2#1D:$86"B+/?#E71'C5E=D8?
@r2623
ACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGCATTGATTNAAATAATAATCAAAAATGTATTTCATGNAAAATAGTTAGAGAAAACGAAGAAAAANAACCGACTTTAGAAATATCAACAGCAGACTCAAAACA
+
:('1,/72?,(G1!"*,H032$!*))0/<$'<+;<9?&H4C0/E9=:5(&75(C!2+C6";,2<@*2C)&-6")4F"E!C?"2'G*DD3>H&+C%'$:/97G%.:510>#"9"H=,9$!&(5F&DHD9'FG@2%13;1:D
@r2624
CCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCG
+
11E"6E;A.-@0;8453"249F5C.=&G<A4#8;"4)<A:CC
@r2625
NGTANNCANACNGANTTNTGANCTGTNANANTTTGAGNCG
+
%("(#)'*!&!%!!$#"&&&!"%$"*)%$!!(())#(#$%
@r2626
AGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCAT
+
-";)>2DB-"B$,%A)>GF-5,!7:.:?&4%F=5#@FD1HA*?@>1@AA#88?5:!?CD89C8+@=8
@r2627
ANNNGCNAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGANGCGGCATGGAAAGAGNTTGCCGAGGATGACTGCTGNTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGC
+
%")#'(!))*+%)($*$(&#'$*#&)()'$+!(!%%!*!#$((!*"&%$*"#%%(#))+&!&!#($"'+$%$)$+*#'&+!+'+#)&!%"'&)'!'*&"#$"''&)'!"*)%%*$&+#&!%*&%$$()))#("'('!)(
@r2628
ANTAANAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTAT
+
%$+*$!$($$'##)'"%($)!&*#$()#&"%)"&(%!(!+($!&&#*(&#)&"!+%&)#+!#&!!+"%+(
@r2629
CATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGTTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAGGGA
+
=,+=.<*;"#8"'0)B-?4-&$@%HHH2DB!$)BC7/*00F1F-?*>A&:A&!GE7G4F+&'*+GF2+E/0'&A#5-5#595',5=HBF-1EB'$>-8$#E/&?&CAG$9.3":;D4=$>'/.@F=)2=/8DHB#0+E&).,,>
@r2630
CAGTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGG
+
("&=)4A4+-6!F569*(<!DFEE&:;>0G)(+:5A!92B67?H*#?;GF2=0-%G:7,+
@r2631
GCATNGNGGAGAAAGNAGNCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGAT
+
"#()$%#*&&'!&$$!$(!+"!)+$*)(+(($+$+#)+##"")#)#)&''$)!(*'*''#&)!%*!)&"+*
@r2632
GTTNAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTNAATGACTTCCCCAATTATTGGAAACGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAG
+
')(!+!$+&"*)**))%"""'#!('$&!+*")##)&*&$+$'"###**""$#(!)!!"'&+"(%*+&"*%##$('&*$+%+$$&)%&*$!$#+!#&*#*#!)!)("%)$&'$("#*(#'(*#(!%%$(&#+%**')#+(
@r2633
TACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGACGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGT
+
/GE=&<4>?6AD#B56/+3#3A:5<)$&G%BA@(846B'3!/!!)-($3<A/:G--,@HD>."9G7:.B')H6679<F!5:5C:GG7F-;;7,/=-F$$H'"@A6)',<(@8?B(F-+#6<;
@r2634
GCCGGAAGTGATTTCAAACAGGGTTCTGGCGTNGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGG
+
:'+B,%C8+#)!3A?AH%.2B3/A2+%+044=*4"9D530@8)9/$D+27@2*,<1H*;F)%:)GH1=/D""48B)!19C-B2'-684@.@/
@r2635
CTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATNTTTAAGAGCGTCACCTTCATGGTGGTC
+
')++&"*%$$)+%""+()$%%!*("#"#*##!$)!")*$**%+"&&!+!+*+$$%#$'**!*$&$
@r2636
NACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGNGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCNGTGAGACGTGGGAGGCGAAAATNGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCANTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGNCTGATTGACCGGCAGATTATTATGGGCCGCCACGANGATG
+
!&+#*#)*''%))&*+&'!#%&'(%(#!!%"+##**#'#)&*$+((#"(+(%'$&&&)'%"'$"*!)'#'(*%"($*$'$$""!()*!%)+')(!&$&%#&'&#(!'$")($*$!()&%%$'(&!)%)"+'"'*##+!&##+)!'*$#'*&&(!#$)("'")%*"#&+'+')+#((!'(+#+)!**)$#!!%'#+'%$'(#))*+#***!*$)%$#$'*!#*)!+($""+&&')&&&#&('&)""&!)'%(%#&&&%!#((&&)&$*&$&*(#%*%#!+)&))*#"!)&(%)+#+%&'!!%$*('%&'&)'(*&#**!++#$&*!%)%"#!
@r2637
CTTTCGGGAGANAGTNATTAGCATCCGCCCATTCAACGGCGGTNT
+
+'+$+&!'+%$$+"#(*+!+(*'#(*&"$!"+*$!&!!")')'"'
@r2638
GNTCGNGGCNNCTCANTNNANACCTACCGGNTATTANCGTACATGNCGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAGAATTTTACCT
+
")'()%!)("!#((!#)#$!")%)$('#%(#''$*'$&$(($#)%!+!+)'%"%"+#(&*$+*"&&#&+%$$%&))!%+((%*"*'"%+&#(#')'+#"#$"('"(*!
@r2639
CCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTA
+
(GED'%7F(-;G9"'61D$G"A9D&0H=>2%;H-#0$+B3:7D!H3%0"(&
@r2640
GAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTCTTTATTNTGTTA
+
21,93;B>8!22+=B5A+#!4,=B";'.#B:C($$D36"=G-@,>2*D19<.2>B=!AG#(5G:),1(1H1.H.'A)G%@,AD29&>#3
@r2641
GTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAG
+
(600?";:0(!&:'37=$(3.E=2>#H>$#:<8F)785BE,?D
@r2642
TCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTNATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATC
+
,8A?97'F+A*(!4%E6+5?/@9H/C/.@B.'/-C'F&69H<0>B8DA)#%<GA+)!',<0<!%?5.391F<A.9EF/'F.<:9F$H%*978&*D&!'4(EB;D165"
@r2643
CTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTG
+
F@799-FGE5D!7B%&HF(6E,)'7/%@A3-/6,H9)'(:3F&E-5B!-$)DC$=/%@9@*%=E#*C7
@r2644
AGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTG
+
H>5+37):./2$G";FC=+"(?(@#G?G047.26$/;?4)9>-B>>>DGF8;!D#,C='
@r2645
ACATTTTTCAACTGATGAAACAAGCATGTCANCGTAATATGTTCTAGCCGGTTTGTTTNTATCTCGGAGATTNTTTNCATAAAGCTTTTCT
+
DH%#5A;B,:7-&$/*@2B-1H=E0:GG==#<'$B6%$@AD;*%<AC@3,"?)58/E@$;4/D#140">5D"EC.ED%F:0(7&"5-&0A9
@r2646
GAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTT
+
&H)5:?#H/13"=E@+5.68=:6(=*'?)9+;!H"((%=9'<C;-"B%6?."?#7=G5-%4<(7*GH957@@,#+B2"8/65GA#:F',B369#G;4%(B/>*>H&$FG1H99<=0C?8F!
@r2647
ACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCA
+
#G-A6'2$H$&9"%)B!C'H,@;/C1%..%%4/@+32*@H/
@r2648
CATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGG
+
).H!51')&+(4+66(B%D8<>74AGG&0EF2,*)<#*?0"'33$$@'-D-;&'3!6CDB25=3.5B,5'76#A3)-H5>#G2*),-7>G.@9
@r2649
ACNCTNGNNTGANNNNGGAGCNNNAGGGNCTGCNTGNGGTCGGNANNGANANGNGNGAAANANCCNATTCGNANGTCNNGNNCNNCGNNNNGNANGNCNAAN
+
$#"!"#$"!#$#!$#!#!#$""#"!!$#"!"$#$$"###$#$!##!#"$!#"$!"#!$!#$!"""!!!!##!"$$#""$$"#"##$$!"$"#"$#$!"#"#!
@r2650
ATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGNAATGAACCTCTGGAGAGAACCATGGTATATGATCGTT
+
8H,B/1)%2.$44F3)C8C8CE-=6G.DBG-($AC&?CH-D3:G6AC$)!5#:+E2!A6:-+:&?$5/:4,?>
@r2651
AAAAAAGTGGGGAAGTGAGTAATNAAATTATTTCTAACATTTATCGGCATCATAGCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTNATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTNTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTAT
+
(&5</H6=)=81E'8$4;7<"F=9CB113./2?A6<$)!EC34F7G'E3'%+,8.=5=(&%;;@F;@6.&%%;*5%2HD,%!F+'HA*833+FC0?82=22B"9B?/.$2H9?=?'!>1/.&6>(.?053AE28;9C+8<<??!7,#E359%<5@"<>-/;D2D9D=:!3;>!2.-!11H$>6&2!C9,3D;
@r2652
GATTTCCAATAATCAGAACATGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCAC
+
%D:4$FG*F&2-.$C>01$5;1C@?B/FE3*GG;"-)59&><:->B9"#?)'807C4@F>A49.1.
@r2653
ATTCTGCGGTAAACACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGNGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAG
+
)%*++)"+"'%(!%+('&)+&)++#!!#)%##!+#)+'%%&+++#''#(!++%$#)*#)*%%$(#!%)&")+%)!*#*$%!)+!'$)'#*!#"%)*'"%((#$$*)")""(*)))'+!$(++%#""!'#$$'%"#$)!*&
@r2654
GGCCTNTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGT
+
,734B=F#(5+F)&96F*6''6=62%H).4H51=G38>,(@8!&&5!",-5!$=6<="5+<8G
@r2655
GNTTCTAACTNGCTTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGT
+
!"'&#(!$"%")'+&'#++&'($'(&+%&!++)*'#))**'&'+)%*!+#'#+))))#)$**+"%'"$"((#&%$")
@r2656
GACAACCCTGAACTACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAANGA
+
&D14.A!(7;<=:4G#;G618$:D"+''?EHH@F31G!)1'A$7?H?.$1A0;BF;)E"*>(
@r2657
NTTGTAACAAAGGAATAGTCATTCCAACCATCTGCNCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAAT
+
%;'&-&%-6*7?8AE5+%*1+?B=1A&:+.@:#-1E*?5D0&/<E=3E(!A$CD.H2+7:<9%41:<:84+
@r2658
GGCAGCAGNGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCT
+
&(>,2>:%>H518#>6F-3F;+2(<4>F7G@%.C,<GG=@HF8"7$F0E7,.3A91H7F;A$2E5(AA25#GE!:A6)),G7@!E&'#74;)BC&5/A)-
@r2659
CCGGNTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATC
+
G13:6.H*$22-75H0BH&1#&2(H'7;;(39B-G=GA+8<9H?.C7E1232"<!$#!(2.%/%9*3&A!<FA,:+!)4E
@r2660
ATNNAATCTNNCNNNTGNAATTTTGGNNTNNNGTNTAANNNGATAG
+
)$"($*#%(#$&#&&%#!$%(%%#%!"(!&&('(!%'&#"$#)%+!
@r2661
ANNGNTNCNCATTAATTGCTANCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACCATG
+
)$%&!$'$+(+!!)%"&$#""*!"!&"'%('&'"!)"$*"$#%)#'!&'($#$**'*"""(+&$($&*$*#&+')'("##(&'%*!!'")&')**$$$"'+"$#(%)$*"&&(&"&!*!!(!"%)+'++')$)"&++(+(%'$+*+%#"%
@r2662
ATATNNTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAG
+
&(&)+)((*#!!*&*'&%'%(++'!$"#)("(!%#*'$)*'#""+#)*"%"'%!&!&+$"&"!$"
@r2663
GTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATAT
+
H09>58>,44'40BCF?<C*7#&!5=B%G#/0<>H?F-%**?76H5*F*=A2'.@6:D9H41,$41;8G';G$/*00.&++(?+
@r2664
CACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTGATTCCGGGAAAGCTGCTCATACGAGACAC
+
;1ED$?&F=,#6/&E((D8?6'A43.7&H&30/F;..(DHC=2)8!GC67;,;A"-A>?19D4.!851/;D*-?85)9'
@r2665
CCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTG
+
%C>(7+(5:31B"-A?10/-,*(D4-*.B'G!6>?<6%$(8&@;G%"'8.:'!1@8='1%!#>8#,H-%?2ED"#6F(B':<
@r2666
AGCNGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAANGATTACTCCATAACAGGGACAGCAGGCCACTCAAT
+
"4;6C'-$.DG;$)4.<7%/.;$?&4';%@&C#)3G9#>C>=)A1!-AGCB&DH1$:@<>$G06A?9(E52.4=;F#?H8A
@r2667
GGAAAGCTGACCGCTAAAAATGCGGATATCAGTAGCAGTGTNAATGCGAACTCCGGNACGCTCAGTAATGTGACGATAGCTGAAAACT
+
?5"6G1B@$+*;G@A",<$HCA279>3F>6*B(G?@E((G?E810"H0E*+=-9(*&0B6*)7=4:?C/,327BC/DC-&:4H<H'&?
@r2668
GCGGCCTTACGGCGTAATTCCGCATCAGTAAGNGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGC
+
:0=!,%4-/&$+(DG#?3#"9?)H:7:,7=F:#A-4@9F"(>C8%%&A'4"C?5>1%9B2;"8+F?.-!*"/
@r2669
ATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAA
+
&>8/:(F"2)$H4=E99"&H))6>/2E7$?)FH?$E-%"E
@r2670
GTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGG
+
-0AF(#:A!."9%@@3(<!&?D)+?B-.40D1525%;$!A0A<F*@?%=3-A0;9)#
@r2671
CTGACGGGGAACTTCTCTGCGGGAGTGTCCGGTAATAANTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCG
+
&)%+$&&""&("('))()""*#%(+)*%"%*%"!*)$%+%*$&*$#'"$$#!%!#(+"%&"+($'+#'*!)+)#"'+#!&&#)%()$!
@r2672
GAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGT
+
<'/"&=51*"-5%@H98:($($-%H;(A/.')CGH.B>9'D<2?A*$2H87>B)-18D.%'%1-H&7?:2;9=3>+05*$
@r2673
TCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGG
+
0E!8(#!2%B?"01A898/B+6E=E=42E$3+?6G#G-G>*F9;A#91.58)<
@r2674
ATCCTCTGACCAGCNAGAAAACGACCTTTCTGTGGTGAAACCGGANGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGAACCATCAGCCNGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGAT
+
,,;)D47F-8D1A4>(E)F#E'3=+D&@:)!@9:GC=FCD*B;8694(5A=+E/$7499B#<41=!F;6,H7G&A1<.C;8F.C2$(.CD=18)+379$:E'5#(7F.)%:FE*>67@:46@".+#3$>#<>9F+!;8.C$4F-=07GA#4@--:+6FH@,<:?"$C&48?5-F5!A<7?76/-'F
@r2675
TAGACTGNAANANTCNATGNGNAGCAGATAAGCGATAAGTTTGCTCAACAT
+
!#)"")!''$!*"$$''&&*&!*+!!*%$""&%'$'*"#")*))+&&!&&&
@r2676
CCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGA
+
%8&E8A!.7,E8=$'=9B)@!?#;.@:,E/6,:/'$.72,%<;>E)>'7?7';'8%:<'*/F4$'/D2)5E)0H6E?6DF;2(+E(8/=C$>'E;6#G7F:(7,A?F>;E4C63!)0H7E590#;F6,:,+)-$551:FBC=912+2=?D<&F&78E%3;>/&HA'@:=/
@r2677
CCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAAC
+
7:9,07>8H<=1!8B)==-()?E<,?91*$(;:;79=G4$5A-;(*3)@?C(4
@r2678
GATGCAAAGGTGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGC
+
/+&,:6FE0)20$-4;$3?F#/1E)>4!"FB1!#'&G297DHH93E9:F*@*
@r2679
GAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACAGCNCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACNCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCATCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTAC
+
;B:1.<)<+$$>)3DG;<52.4-<#:/3G?26$1;H&3(<%3&-(,?+&027/#98*3/*FC!(6:9<CB/#D'*52<"#D0F$D"(>*$@D%H5'D?F91"0A&F7?!6'#>%=3>+F:<!E9GA"0742/C?39;HG;F'>9*#3'$"?>9):3518<CB10%%;(;<8C::;:1DHC9<,=*B&7;"$9;?A@B/+():),646*("?;?-'4*.B!@94E0"#3H,)B-40)7@*,0(,B.(33A5:=<;B<235E</7/,!A;?6=C./,*E4>3.&@B;##BC6&*/6$*?E=0G*D9$49/B:GG#@D-$$G9/8H;8CFD$G:7-&!@&@A,GA%#&A5A!*!.D$!4
@r2680
CNTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATTCTAAAGCTGAAAATGATGCTCTGC
+
)">HGDC)A)B8A"1C51>#((#<FF+<'%A12E4)/%H"&>=;3-'E1<H=>=)B"%0<A='0(D%,)64&<H?&3137>D)-45,E.A95G7?8$4=/E('#>4@-76%&0HF"@DA:(A6*&6,B55,7GG/B5D-<0A#)+<:@HB:E3
@r2681
GTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGNGATG
+
H@5@F;6608+,5G3+4>G089-,C91*21;*'806+5BD.&FA@),/<:20818
@r2682
NCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATNACAGTATCAGAAGG
+
+($"''!$#)!+"$"('$*($%"+)'!*%"$%%'+#!*#+**+$#*'*%'%!'$#$+#
@r2683
CCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGA
+
26;)(*=:0(2(*A!F,DC../F/*7(B%>877?)?*EC!(*.71362<C$F"6.>1F4';.,376#7(@$*8<9!H1C/'
@r2684
CTGTCGCGCTTGAGGATGCGGACACAGCGAGAAAGGGGATAGTGCAGCTCACCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGACAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCTCGCTCAGGGGAACAAACNNTNNCCAGATTGCGAACACCGCTTTTGTACTGGCC
+
;2)A?94-G,@G:?F'@>A;4046B!/;!F=:$@D+23'>H.)%/+E??!4E?)G!.,=))?*(E:$9F936(2BF&6?4/>2+:H<C)9>=93&>3DD524G*,1H&E%C.9*5$%=59176%=A(+-5D4/EF*&?;.<1)1A"8A)D4>2>C'B;1."/;=@06=A&39!7'-G<4C6<A6&<F;3-"@;$&?3=502F:B3%="%2A!,>?2;235,1>6G:%+H;7A)E,
@r2685
NTGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTANACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCCTATCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCTTCCTCTCCGGATAAGGCACGGNCGTAATCAGCCAGTGTTTTCTTGTTGGTTGCTGCACC
+
*#@7F97A-0B-,')6H0G471D5").2D>&>$&G(B2(8!!F$'#6B#:<$;4-C=>(9+:AG!'?+C8!;9%>=>,$75266&=$EF-!H4)<,@:.7:/E<#G31<%$6&)CH#E02':'91(-8B)2(!:0)HB4$+1+9%EG()%C*7$&6'4;F79!BC+)#@7;#'12(41(3G*?36?*"%1!#;B#7;$0?,25=1<(,A@%DG;4("1?F=/C@8.#1$0!5'G1<-4GE$-9
@r2686
TTTAAAANGACANANTGNGAATCCCANCNGCGTNTNTGTTTCGCGGTGCTTCT
+
(%$*'*'!'%'"###&&!#(%#*"$#%)"'%&$!"!#*'$##(+$'+%"$+(&
@r2687
AATCTTTACTACCGCAATCCACTATTTAAGGTGCTATATGGNAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATAC
+
64&);;1>AH8C6163$8-*,7.8D0+3#E%>>A#HF)A1)ED.133%E$&-=6:>+H8;H%,&*D!>!'=3&$HE/,A5526C+3.(G;-A;;
@r2688
CACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAG
+
*E)38'7H92:1-#,7=)0@D!!8H+5+4/7B#/-;-93F-;
@r2689
TGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGA
+
,:C>,,5)#+#@-'/85-@+3D;:&C@HG$<$"4%737$2;-#9@$#$@G@*<EH-06DECH='#A
@r2690
GATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACA
+
>!'F807EB"DE/('B=#H05*BD@6,&7@@%HF/9>&2)$=%
@r2691
ATNNGAATGNTCATTCGANNGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAAC
+
*($""*!)*"*"&*)'$('+#++($#$+('(*$%+$$!"*'&+!*%$#!!$)'&((+#!+%$(&#(*%#(++!++"%!"++"*&"!"*))($*#($)!')$)+&*&+*'!+'!)'+"*%%+*!)+!('&%%+++!&&+
@r2692
CGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAG
+
07'1@;FH/)=(;:+'*?>;2C(;.$8-A?&15/52;A%$=1'(7(*9C6!'A?D*3?%:%=.<5*7B&&C8&C:1(.B:3>,:)C<3$71;E;<#8&&ED%50D199&/=01/1>5.(4A<5"%+D/!"<B2.)+=174769+C,G>8!0$,,*%+E)C=>
@r2693
CAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTNACGGCAGATCGTATGCTGGTCCTGTNC
+
+?"$G-54%8;(B;);</$)#4/5:#**@G=(6@;'4"47$6A&-?A1/=>/:)"0:',,-"3FBB<
@r2694
CCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGC
+
8C4,4*8,2+;C.@;AE$3)".'F-!?(B7+EC@0E"*40HGHH#-#
@r2695
CCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTNCAGCGTCTCATCTTTA
+
=-:<&6H@B82*EG4$B.C)C6@&-#B361&+>-;H<!3B=8-;@=6@">33,A!@'*;6"5=B@>G=%>&3,C/<F>E$A5"%)D1/BA,8+27
@r2696
CCGGCGGTAAAGAATGATNCGGCAATGGCGGCAGCCCCCAGGACAATCTGNAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCCTGTAACTGCGCCGTTCACCCGNACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTT
+
0.C$A!,3GF!#&42=2$9E531-@!8>7*%HC.B*:.;"0.?#AB@.E,G4?9@56=-D'E5,654HG9%/)=D)1)3'?%4A<0?>FBD0D-61/.;1?5,)-<</0>%A5/C262.A2=(4%#&H!4,AD7?$:02*'%:<*5*$#,!,*EA<@!46:6>68/G+FD48("-@'9/+&)967-75H/:@B$1":8@>1#'1DH))?4E?)!/20:(4'%/69/1->%1GBF3#;>5"%$-'%/&:8%;**H0
@r2697
ATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGANCAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGT
+
GC05G8,(>+2B88,#?3'.)DA!0<1,>:@4E!E'H*0B$-!<1C"#:+*%(3&$.)=)A9#'7B8?D5@$0.BC93*E6C77$!54"&797*@!(!%(B)=&5,5&+!,?"E5/9&*FD(?9FE<72<+.&A:EB5;3?2->-*H<)3#/C,?:D?!>F7H&F+4=%F./:2ADG&/=8-@&#<@6HH$-3+2&,/$)8E92C%6@A8G=9=54.4G"682/8=;>,
@r2698
AATGACAGAGGAAAAACTTCACCAGATTAATAATTNCTGGTCAGACTCT
+
BA0B)2C:7/AF#41&#*F*H5#A%583G7)(>$2;&D*:<;85=#2F*
@r2699
CAGGCGCAATCACTNTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAA
+
#4=.:-D;=89C1C.7:&@9+H,+*@E8@='06G5@A:=!?.566C7H)E*F;/H51E'(01@55/'&?$.#5*"GAG44,HCG6.:7.'D!%.%4H*24(4)-!&&G:=%B@;8=-E9$+;D;C%2:+928)7?2
@r2700
ATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTA
+
G#+B%,@-E0:E*<:592CC00&+DD*"#)='*GA<8:!39A*E"3A'.E*.D$,.#"D4@507=?*;'<.(43'.:G%1;
@r2701
TCATAAGCAATATCAACAACGACGGACGCTGNCGGATTAATCTGTATACCTGCACTC
+
8/"%@G(:?BF2C93>>%$D"(/9!0C-68"F#57&%<"+@#AD33"H21.&2!,=?
@r2702
NCCNGCAGTGAAGCCCAGATATTGNTGCAACGGTCGATNGCCTGACGGATA
+
#+CG%/-2$B=(E$)6/?"?<D+++')?$9%0E2;5!D7!?A3(;"<8/):
@r2703
TTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGNGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAG
+
=G(-@'5$/20";E#-9))5DF3"20@!A.#>G@#F<?":/?@;)B@-D"&;#$,-8&@C>3@G$-40',/'HCFFE9).1"=$H98.6?8721?"D!F4A2;,$$-4C8C#,FC<:AE?0'@@G+.-!3-/=,8::3=###H-3"C
@r2704
GTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCCTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAA
+
=9E,.GBB4D=//"&<772A03B34?8C;%78EAE;??BD#+7<=5+GCE.H"GC1.<5F+2<82<5=@#'41+H$>$2D@A$F;=E+?AG858>@G':!B>!/,+<-EHB.9%=F@F5G;2C7%*?*'B5$2
@r2705
CCAACAGGGGTGTTACCACTACCGCAGGAAAAGGANGACGTGTGGCGAGACAGCGACGANGTATCACCGACATAATCTGCGAAANCTTCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCNACTACACGGCTCGCCTGTGGGCTATC
+
(F9&0/'DC=36AE?,/G!,+'@"9<3,B;G<'<<?F0$"A79F;(H<*2F'A(4;,:H$1*/AH,*9'F0#?)'%69D85-$0%$6$6BD$%=.'!HCC)18!0B)34B%A?761'F?-%#HFH50>;$(!/&="-E7*;>(7./=C!4F'=:8+7.7B5.H8<=%:5>"DD:?<=/.%'B4%8(7=
@r2706
GNNNTGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGAATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCANCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCC
+
%"!!%+)#''"&$+%$)#$(+*+'$+%#+$"#%&)$*%*&$)((%##+&(!"#$#!*##$%$(&#&#*&'+&$'($$)"$'+&'!((&'#)!)!&%*%%""'+%!$)'!(*'"%(*&(#$+#(*$#(+!*"!#&#++)(++"%!&""!)%##$'$'%#$%''$%!+$"%&$*%(!(!!+&%$%!!#%*'!"(''%%(')+(%'**&*!$"'&"%*'#%"'()
@r2707
TGNNCCGGAAAAACNGCGNCNNNNNCTCNCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCCCNGCATCCAGAAAACGGGCGTAAACCTTA
+
#&'$$"'))))""%!%&&!(!&(&!&!!%+'"&$$*)#"!("($%!!*+(+$*#%)"&**''#%%"(**#$%%&'(+(**"'*$&(*&'''($*%##+)#)!$%+(!$&+#%%"+&#$$%(+"""&"$$#)*((%$*&&*"&#!&($&$&&!"%(+!"%%#(($"*#!&*#*'*"!$!$%
@r2708
AAGGTTTACGGCCGTTTTCTGGATGCGGTGAACTTCGTCAAC
+
*8:0:C8%F#-#&H+4#8*;0E+C+B;A!!5&(H"%C%?&>D
@r2709
CGACTGCCACGGCCCCGTGATTNCTCTGCCTTCGCGAGTTTTGAATGGTTC
+
2@&5')6?659#1F/#;3'@H(=2A;-#1'(?@,C$C2C6,@:F=,'G?"!
@r2710
TGTCGCCGGAAGACTNGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCTGCGGCTGCAGGTGCAGAGTGATTTGCCGTG
+
*2F-@!$<'6D"$!C1,.-<GC(#AHCHBF,(<FF@F5"DG);7BH-?9B2.(F31D9B%D0<A*9G):2)G$:@0;%G(%1&*D?,986<4?4/;(;;85>5F('"816*0H"9B>?-9((06)*/!0C
@r2711
CACTGCNGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACG
+
072?7C11?)=H?5D*9,4.2(1D$0-7:2>+G=(723$=BAB%/#:&$-/'H;4
@r2712
CATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTNGGGATGGCAATTTTTACGCCTGT
+
214##GC/$=/)5/EA3,2H*&1'?=@*3-=<9+;@HF4G@B*,"'$)39D7+#E;09H-G<-'#<H&;#,!@A539#9B
@r2713
CCANATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCG
+
#F'H@012:.,<6<-(*.><!981CC4$B-13>1*FEH$0@"3,/F%A69F=FD$8D31)+"H#
@r2714
GCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCANTTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGNCTGCTCTGAAGGCGTTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATT
+
7(@<.-%>4"-;03D2(2G:.A1'#61:G'E0D/8)B&1*=F1829+C9)0@%;5G.5)#*64='"E9'8#.#'9.1293>@D!@G<&-8*A!&5(*C'=0A8(24#:*;16<,>DD6":A@2-*.9"93%C&@*C+,=/F>BF2-=(&-8G&-9C0AB(,EH-@=?D*'<.1/8+F09E
@r2715
NTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAATTTTCTTCTGC
+
#D1".3$(61=!%ED:=B7@304/7&0*;C9&%2AD1&D&:5G('3>9+GFF*+C!3
@r2716
TAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACTAAGACAGATAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGA
+
1+'7+:C=5'F+*5(8!4-(4'7@AB)D/";6G:-;2,.?AF'<*5.*)'../C3D49#BA+)%6';E*$A18@?.D<)$&,/F((75.HB3H#45H+9/C:F0@0->#!563%@(478%BH)504@!5G'G+A*F/=@
@r2717
GCTGNTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTG
+
:-B@0B1,#E4C(58&,(>%4@/'D1$4',6)4=3-75H15+0A.6*3?;@D,!)!A5'-*CD4&-D=-8)E3<+=>14=36<1472>,1E
@r2718
GCATTTTCATGTCATACCCCCAATAAGGGGATTTGCTCTATTTAATT
+
,?>"E6$65:4.3#D86B@AG6%>11/&#H&8!481E1;',*%*<8+
@r2719
TAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGANCATAAAGGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGG
+
2')0-/A/"+A17.0,!$#89%<:5-E='"E1:,:.&,&;::4D!26H/@-.,F9F%'&@61=/D@%022F?=F"7#6'8;2DD6DH(&0G>8A:F<:,A*/6B?B-D%037'&F"H!-%D<4!9;?.,D*BHA>F#177,#'#8)%#*)2+'-&73BG1801@=-9?HG?+.9,4H9;%3$$E883,=-?"$4>%+CF175%,!@0"A8
@r2720
CGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCT
+
.0("$=6%CGH25@$%G2D5)6:*:,:99%/,"?:=72+.%0(+7=>A)/6.+
@r2721
GCATGGTGCCGGGAAGAAGNATCCGTTTCCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATG
+
,2AD;=:(+%7)!H=A'BC78'652$2@+B,,6F2*6>@"<<56#*;:F;%=#(HCE?G+#7DE#+
@r2722
ANGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCAC
+
(#G;E@.2'9<DC4+)!,5'?EB=6;!$!E;@'@56%':%%$<D'/;)@:A;8/FF051B&'0H5?#H9<(>+#?/$+)11'@<=D3:;EB*?29%&!3,G-E$!@$%"HD0
@r2723
GCATCAGCTGCTCAGGTCGCGGNCNTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCNGCACGTCCGCC
+
(&(+"#*%%%)*%#+$#$'+%+&+%*$'$''$"!"+$*#)(!&("$##%+$$(+'%(#&(("!*!)!%)#!+
@r2724
GACGNCCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGCCGTNGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCNACTGGCGTACTGACGGATTCATCGTTG
+
>.?.6F0@5</+G..B'>H23<-4(A6G3>A6GA'"HHF'(&C.C9#"C:0>8&B-.H:;6:!7%"6G<'1CBC@.@@A-1H.7#?>7<::B233D0.3+;A.8?*7!/8H0.:D."?0D2A3:##%*8"9E5"3/.0G0==2%@-917$=&2-=*+?&H
@r2725
CNNNCGTTTCTGATGNTTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGAC
+
&"'"B0:=H9!:'8$,>4'FE',H*G('"G1=G0)H-8C4@E5B$8H.%22F-;7B55#9%E'?9*"A("E,.0$).#5F59C'&@CC7-<@GH&.7G
@r2726
GCACAGNGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCG
+
;36?'7&7F<B?>E"-(=@4)0$.2@?6$49=H.&!<!<%+$@93>47%";3HE&C>9>&8!C@5<A%#.*.;9/(9143'@&2--,0D"5
@r2727
GCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTG
+
8!>C,3@0:/57+.H;";5:6G#B!D*+=?%#&GB>F,D:A*)4"G@&34<#+"/70@
@r2728
ANCANTGCTNNCTNNTGATGNNANNNCNGGGNCNNTCNNNCTTNGNCGANNTGTCNGNGCNCNGCNANNGNNNNGANCN
+
$!$!!"$$$#!$$"!$$!"$#!#"#$"$#"$"!##$#"!##"$$$#"#"!!#$#$#!"#$$##!###!#$"$!"!##!$
@r2729
NTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACC
+
$?1C'B3G@(B7---D-H1GE%++A;H'1+;,$;8$B"4A
@r2730
NTNCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGAAAAAGGCACGGGCT
+
!%!%'+!%+**+$$'!"+!+$$%+##&#%*(*''%$&'$+%%")(&$)(%'!$'*+!&#")'!%(!(&"(%'%+"#%++((*$*#'"!&(&"%(##$%""&&#%#)+"'%+*#)'%#("'++*"##%
@r2731
ACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCNGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGG
+
F4D'-:'H@04@-9?4)9(89&D3GB%B<@>%>'<%++49:,A#8%9?*+6+:B;&*&-25$<;B'=5"+F0C4E)+6"5(4+>88(0:=
@r2732
TGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAA
+
H%=-$(F#>@+>*<(1/!F,*<A@?=/56+&%?"1-)86F1"))"H+G2G473""D-67)/#</6,2@D.F9.1;(4@8<3D@?:E2+-;:62)191..4&:1"C2G32/C@-:A&GE9FGA5G#H.,;<<F)*E&@#FG!'++363@
@r2733
AANAAACACTGCACTGTGTATTCATTCAACGAGTGAATANANGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGNTGTCAAACATCAAAAAANACATCATTGATTACGACTGG
+
4!%<2G,HFF#">'/E7,D!3=)91+#16C8A.9%H,25H)/>/;62,#3495&6C+8-)52$#$.F9#(%2&4D5-1"H&;*.2=>#8<;D,1E@:!!(&G'F<<:2?*=E*F$82C1>(A9$4#31)G=>/5))E7-(D+:-(21,6.A6C43-,:)BCEFH!369+!1E):"5++=*;#.>%!<4:
@r2734
CNNNANNNTANCNTATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAG
+
)"')**!'*)#"(!+'#+)%"#)#+"**'&#+'##+*"%$&%+*$#*$(#&&'%#$+%!+!"((')##!%+#!''
@r2735
NCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGT
+
($+*&*!%('%#&+*(%'*&+("!#'&$*'"*)!+("&#+**!(%
@r2736
CCGTTGCTGCTGTGCGAATNTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTG
+
6:342(4DA+5:0*0:#$#F>!$F.%7!62=@@>&:=/$8E/://FDDB*D="G<2C&3G4'(>1F"!;0B335@?"9<D63EA+@?>$;
@r2737
ATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACNAATGGAGCAAAAGCGNCGGGCAGGTAAAGACGTGCA
+
(D:73E87&H&3C.9@<75D2DG(#B28.F"!/C#B)*%9=*?H7)!58-),!%(.A@9A22D!E*:DH9D5$!-2:;&EFDE+76
@r2738
NCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCG
+
&8&"=,9:F-,>1"9914<:6(+#(34;9G$H7%<22265.#62(FB)D-6.18(:F+0#($=:F+
@r2739
GTTTNTCGTACAGTTTNCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCANTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCANGCGCTTCAGGAACACGTCGTTCATGAAT
+
7"@>4#&B.@&$+1?E@H="/F:,8$+4@1!//*AB6E298,&&E)58<H"!<E;@7H3H'G1G=4DA)0H=/6.922F=&$GA,6HH#>>06(#!!/*;41!$1B1?5'@.G#D>3C-1$#.%42F755<18?.)@A3EHA+<-!,$(%7A%398CG%-CB5.'#14>>7'(*"96#FG';,&0:>
@r2740
CAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCT
+
=!"-2=@$G@$27HB$4?H!H?H4,7/E7/'7'#'$3#EG.F<&@'F..H!E!<F+G#?D=1FA1E.1(7,+,1!07.CA+7=(!EF1%+H/(81<++A=F11)F5B,
@r2741
CGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACT
+
4:ACE#)8:%'E/9GDG=4B)'(8!<2A.@:(FEG&:=%,8;5@3&?CB>?3(7@?49A@<*/BDF2@!$=)-;!)
@r2742
ATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCG
+
/A$&4'6#"7?#(9,$(*/CGCE37?7(4C,>$6*FD7!9+;:%&4<!**#7
@r2743
CCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGNGATAGTCTTCACCNTGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCNCTAAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGA
+
*+'"*+%)"%'!%%*'%+)(!$(#)""%)(**+#'$%*(*!'&"&++$!$)#$)+&&)!&%"*(+')*+'#)(*#*#)!($&&&('$"!&*""%($*"%#*#!$!%$!()(("))'**&(('$"&%+%'+$)+$!%"%&&)))#(&)$&$'*!%&#"''*)$"'+*#!$&#*%+""%'$"(#)()"*(#'*"%*!%$%!%$(!(#!)*#
@r2744
NGNGAAGGCNANNACGTCTTACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCN
+
!*%('#*&)!"!!*'&&&+($'"(!*"%$)%(!+*$!$!)"!+()#*'($!$')+%)!)+
@r2745
GCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCAGATCCGATGGATACG
+
@**/)@C3@.(;B;,,1C:491A6(@3!.2(;C69#3>#7?B"F8)8&:?.H;2C-;3:()?=38H;0H#
@r2746
TTGTCTGTATACGGGGAGTTCTGGCTTTNGGTGCCAGCATCTGCGCCAC
+
+$)'!($#)!#&%)+)#+)!)##&(((*"%)"(&!$(')+&!)"'')!"
@r2747
GGCTCAACGTCGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCA
+
H6,&0A/)E.2:,7+E0@+<$23B630E=61>F68!4?*##9C"6!3)EC"<&H&$126,+)5HCG#-E">>?40=A!#*/-'"?@H?+H,EC$%0@D!<D@0<2-&+A70A.66E*=89<+9<B728>**<$3==*HBA#$D.&2H*
@r2748
NATACTAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGANTTAAGGAAAACAGACAGGTTTATTG
+
"($**')+"!''"#'*#"!%#!'*%"'+(*")'+)$&+'+(*""+'!##&)$##'#(+)%"+$*"*#%!%))%!)&)&
@r2749
GTGCTGTTGGTTGCACTGCTGCGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGC
+
AF;">6F4>7:#?<-;5#;?%50,.84#266>+G8:.3>5!828%:(6=9!)531>(%8G6*H
@r2750
NANANANCTCNANCGGNGNGGCTNCANNNNCCGTNATNGCNNTNNGGAATT
+
$!!""$#""#"$"#"$#!"$$$"!$$!##"$$$"#$#!"""!#!##""#!#
@r2751
NGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAAAC
+
#%&&+%)#*(+#%)!(&&&!#%*)&'(*"")+)%&'')))*+&'!&%"")*(%'+')$*)%)*!"&++!)''"(*#)!'"'&!%'($**###*
@r2752
TGACATCGGTAGTTATTGTCTATGCTCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGG
+
:CB3>/A%%D2A:/135>@73+;%EC/0)@>0/&1=7A;H7%;E$+B>H1#>)*H$?/0(/B;#'-7(5@-DC6A2FA-8!2HA8=**-<<
@r2753
CTNAAANTTCTGCCAGGGNGGCAAAAACGTCCTAGACCAATGCCAGGTCATC
+
)$"+%'&*&"+*'#%$*'(')!+!*!''"$#(#&$&"!(+&#*%)#*&))&)
@r2754
CATAACTCTTTTCCAATAATTGGGGAAGTCATTNAAATCTNTAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGANCTATATTTACTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATNACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGG
+
'*G%5D61%E//>A)6(E49.FB@A%&("#%8:5>-,-FF*4(@&;5<+#.,@2)6*H>4;4H6<+!$G4387$$G4.<$)7*00??-=,HH%"#(@3><5BBE+3$C-&;C6F>0H3=D,?H:#9?.?!.$">@H*D1(E'+DG.*/$./8'6";?'>$>6?AC712(DA=2@B,@:D"7F%0@6D'>34/4<B5<!3<+46)A515:B%!2HA7#<-DA1F6."4?,1.-27G'8&,++!#2@=C4)0+=.@5!6?,A68'/85#GH&)D"1B=6)H$=<*!8
@r2755
CTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGANCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATA
+
AF+,EHG;D//7#4!3%G3H17&A<3.+##4@AG'';2-;A;6,;783D:!29F?<205.;F3>1+/1=18+04=,4.",=3G8?%)'D9<F-$-*1/,D1%58<C(2/B@C&!'C!:!B4&,(;&.-';1;'
@r2756
TTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCNTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACG
+
9$H@7>?5,H"A*'49+6-(>@9GF-B!*0#!=&C;=<G5,,4G-D7GFHE57G=1@2#H8@2F+/DG;&G#5<<A'@F!!.H63'5F1!F"1%%'1G3A1"70/8!D50C""%,.:*CG:>F%6&AD'17;#*8@
@r2757
CTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACGACNGGGCCAGCGCCATCAGCGACGGAATATCACGAATAGTCGGCTCAACGNGGGTTTTCAGAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGG
+
')+'+('$#&%''$)"')'$'%(*++$()(()*#&$"#))##")%#+!!!!"$&)'&&#&+#&!!*%(!())#'()%!""!&#%+""*"+%&+%##(!($#&"%'''#&")")#%"*&&$*"%'(*'#)"'!$"&'&*"'!*
@r2758
GTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCNGNTGCTGCTGTGCGAATTTATCCGCNTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTA
+
&83%1GA%%20..=2")G;!#G=4+(A8"5-+*G;?(+!+1?#="&*7&/%13CC=?3>'45?-EDAA79;>-G+#?$+!8;*=D?,68GA.()<-"$8.*$!;?)-7,/955B9BD+E/>8>4).4?7@(A/:(!.F<=;0GA
@r2759
NAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGG
+
%=%4&!8F+!>E+HH0)6!GFAHG*1#F6C/)"A%%,B?B4*3,!!G.FD?041@//-)+F&8$H@=&/><>.@&9A*.A
@r2760
TGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGT
+
AB;#9+<C$81*'8G!D66'>/D>1+C/7=C/?:0:9D$&D43BD:16(@
@r2761
TNNGAAGTCTGAAGAGCTAATCGTTCGGCGATACNATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACANGAATAACAGTGGGTTATCCAA
+
%#!<4>>+9%5%==>:1A552G,=30$/3:%>)>>-@@('-:G&D3;.74:$.?B>D-D"0B;;$*/<GD35###G.$,/1*7%")DD+)?=;?!6E777D/A"G)>.;
@r2762
TTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAA
+
%*:F0BD1EB''F/8%*&;7!F$:<3:,35*DF#)'>%>)3
@r2763
ACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAANAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGAAC
+
3?52@E)3@*"G878<.:B);?(F.<$EFCFAH%!%%+F14G/.H#+00C*F6E04+$C>BB.DGE/A8?80$A&5A$*H7&6E+'46F9?A"A@8#&=<?H<H&=AA$<#6*B3BF-+BG$4=0#':D9E'??44@HA4)<G
@r2764
GGCNAGCAGATTATAAATTTATATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCANTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAGATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTC
+
++;?7%*B0;?.*;5A=-'H$EE-"3G2DCG*B32)0B*C?,#C%0)A5*4B":8,/%053H$7@&#9@<8B27-)1#H<=01+&D'+@H58C@""<<A+7347%%-++EAH5,'FHH+2;=)F&4EEF806+5,G/B?D@/*36E)+@.9$G!(#5/H;3'B1#,EGCE>+%G<9CG-B1G58G(,.5*=72HA<G;0682GB?6+1.:(!&E'1&>=:$<6)+5$6'E?"5<&",AA=7,G!6E&.B8AB>F12897=@<?G2A('3-FBF7CG&>"2).:GA.++<@,!55,E,..69C"E58=//G.5%'G8"6B#?B$4F(>G1#,82)()F1E:(,'$#:37C&@E7!/F6"4#6
@r2765
GCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATC
+
/F6/8G4+#H+(H1@%+@"!*B.!#FB;*)G.40BH0-E%C".,>7>%,<H+<3;C'-&$".'73*
@r2766
GCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCT
+
/'5)660E#40!=(!;9<$"A.030FG73BFCE-)*G<2@;(6-2DC&&$)0@)
@r2767
GAAACTTGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTCTAGCAATACGCTTA
+
$-+B95-H0'H,<=D8:#44:.;C>:*(@"+=13+#03/&%E!".53<C=DA!%%$
@r2768
GTGGTTGTTCACTCATNCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAA
+
4C$@5D=G:*474)HH-9GB(:!?F3$/7;,!*,#6G21+-DF)?(+/@H%2*-
@r2769
TCGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTG
+
$*#+('"""&!*#!)#')&%%!$'#(&$'""&%'&!()#%&'")'#+$%&'$(&+""!""*"#*&'%##&)**+$*%!)"'$("'+#(*&'"'!#%*
@r2770
NGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGAGTTCCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCG
+
$2+1=.:??+3).$HH'-F@)6>:286=7#F5E2D2((/-%?7/<09%)8%$/$=-.-%#$9<)36398<)01)5-?26C!20#"A!9#G2DHH9>3-5'8HG"//&=;7=7A93A-5'>A&AH8>*:8HD($-+D&;5@1.<.5A=H;'B:6<1+/GF7#G$2/'4%5*,FGA())F4E1,D>C58&.!5;28$!C.1>.1
@r2771
GTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATCATCGCCTGGTTCATTCGTGACCTTCTCGACT
+
'66**D?%6>B?),6@7DEH<$B+(G:6)0E#+C)*,+;$<!H<A'F6&H.39+46657GC//,C/!4433
@r2772
CTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTANAGAACAGGCAGAACATTGCCCNGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCG
+
C7#93G5(G6:FBC(1.*F6:@D=0:0DE%H."A1443/;/D1B2=$/>(*,D14)&"E!A(2C#E6)!7!:()6F+B+,'%;'8#/0!;B'B,/,'3>F3>2:63<"2
@r2773
TTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGTGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTG
+
8!D?-3,'&B=6041667)*(>H>:,&=)G)4BAB#"32#A:B)+1<>"282=:9=%$*")22'*4)"-DEF!F42#80<'.2)1A<7B/@/";G6'D>8-#2'CF<-C<H'$F)>2C/21!'!/#*<>GB"$,70+H$)D?1$2>.&+2;F62H:&B7&F
@r2774
TTGCTTATCAATTTGTGTCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATAT
+
158&3;$A$F%(>/$H+(.8<#5)6+F-?E@'9"*%("G%4G!:8#/F;<B8GD0(%,#%$:)7+?H#,<
@r2775
GACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTGTCCC
+
9!/4(*;(6A".#'.5-<#1/>G!E(EH!%*%B;?4@0F,!/"'C*F-+$GFC<7"
@r2776
GTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGC
+
45B@'33-/D.1(8:=>@&6=3?H1B;3@1,9E52DB0(9;>%;"%.@7@61479+870,%=2+:(&2=3D86(3
@r2777
GAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCG
+
6**970719=">23*!6B4&&55!9,"#3)2*?49#E?0217>4+.5.(D#+32"*9E'7%EA<3'ED,:?5@,..+':.8<6#+#+!G$+<8H:6!:G@"6??G$'8-H99E)13.-0CD)%8>3*'.=2#7G$E(5"-6
@r2778
GACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTNATATCTTTTATGTTCATG
+
2:>#2A.:4@&?F5*%"8C05?F#+-<HD(!;28&4+?(*-302C>B/*@=5F2&?99:F:4'5%!&A,$<76/E"+<-;"/DA".AF4@&#&=?;>7D/9
@r2779
TGCNTTGCTTNTTTNTCNTAGCATNGCCAGTTACCGAGATGTTCCGGTATTTGNAAATCGAATGGTTGTTGCTTCCANCATGCGAGGATATCTTCCT
+
&'*&&'""$$!(#)$!&!$"(%*#"#!")'+&*%#&'%$()"$$!"$$&%'&$%''($'+"!$"+!$!!+))"+++((%#%%()#%%"*""!"($&)
@r2780
GAAGCGGGGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTT
+
@;"H9%9%8"?0#&#$.9+5D'1-))$C.>?%,<=E?E,5=;2B%"
@r2781
CGACTCCCAGCTGGACCGCTACGAAATTCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTA
+
?)0097$H@2EA3/7AHF"9E3?2,7(1E,<)9&5>3>7)6H>3GCC82,'#<.2!2G-::!4:(--B387(2%0C2<<09-&E;4
@r2782
AGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGT
+
74E$G"H,9:)0,E:F(!8F"!C6)->:)#,3C(0!E.!):/2H9"
@r2783
CGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATC
+
CG':/@&BC+$6H/F#?(+7)2DA4&7=7A*10,027BD*>H);!F%5*A5'?43
@r2784
GCNCCNGACTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCANCGGGCAAAACGGGCCGCCATTGATGCNNAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCNGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGANCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGNGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGNCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCAT
+
&("$$$)!+'!#%#'$&+$#"*##**')(!$('&)**##$+%!"#+++(+)&*%***%%('*$&!#%(*##%%"*+%('($%*%$+'!'#&*$*+'(&$!(&!"+))"+($+"#*"'&!*(%"&(!"+%"+&(+*#%"'+'#*(!#!&!"')'+$%*%&'$$$%"!%&))'$+#')"%%#!#()+('#(*%&$+*%+'#*$)##$)*$#(&***+'+(%%%)*#)(#$&*+')(%'&#&)**!'&+'$*$#$!(%$"!)((!++&%#&"'!"#!+"&##)+&%(+*&++'#&$)*(!+*+("%$*$(')('(()*+$)%'(+'!$'+$(&#+'!'%'&"##&)"$!!&)"+%"*'"'$'(&#)&*+"%"!&(#*!((#!'$!#('%%%%+'!&+#'+#+""&(++%&)%!"%$$$!)!+(+"+')*!*"!')"##+'"&%&"#)(+!"+!$")*(&*'#&''+(%$'($((+&&'*)$*&%'#!#!#"##&%!+!%')'#!#%$*'*#&"&')))#$'+$"!!()%"!*(*#('(#'(%+%#*%%!+#'"'"*$)(%#*&&#"'*&%+"(#%$%&(!
@r2785
ACAGCAAAATCNAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAG
+
G#A"#//=2A1G!GH:>=CCE-BA1+%G.H0644,?9.E3?;377E2=<C(F5!,C12=:-D84#2
@r2786
NCGAGGGAANTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGANGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAG
+
#97E#;/@0-=?47E*)@G"?BE"."CH.*#?>"**,*/-6<'B>:&259:66?AH606.<79B;'::4,D'GG;814<CA7#7(<;:@?F?(349A6/4,>=;;B$9B3>;EF"0(53--1@!732E'F3(%%?)DG6-8C2EF"2;<:9</@9@,.%6$3,D-A7H6/3;<E9$)H;3<CF.(6."%5";B8A4C-*"85@#8,'#6>,!0?G?+($E<8=2541<.'"C4*/<+%"?E+D6?C7-9!.%2(0D"()*)).0/%'=-4H.!-!7E+<:.4(=7$H+C'4'2''/$BB%G7<>"00:G+6C+*2557;3
@r2787
GAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGAC
+
8&,"D?',F832/'D):75!A5;3+*B"#'8<<6;<DB9:-@8"7726A7(.G?F>>!
@r2788
AGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATNAGAACGTCGTTGACGATGGCGTGCATT
+
HH""/:)B$17=:D"8;&@"='>)1D.8E$2=8'/<B-9A'-0@&;!E1B;0"F)H65%6);!?'<=5!8B8:./'7,*C;=&<.,D:D94)?26&<819;@F9;0=7$:B!HE5>(;
@r2789
AGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCANGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGT
+
%HFGF9"!!*.&7(+=,@"FE+FF$$,F,C.6.#CG5)<-$4";B;/AH6:67?/#-%#&-/'!GHA=&**'G-C/7;@2=(CB,')@A;$1'0C?HG0-&267FF,A!6ED*$:+;;)1%8)B9-=:H@(1$2H1$2D1;;/!+-AA6#G1+5.35H,%($EF-0#C("<!B
@r2790
CCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAG
+
5(H<'$=D9<<&.,4F@1'8&G@<@805!#F6*:%#*!=943F=1(G/*.@E8-G/>3@8?6*!2F*$2=8>.?-)+F##&'432?4%17F6(/&;)*G?!7D%095@*>*7"C?&3-/B7&<3@.&F::,:#872H#+@7+3@:.7CC4F:'E2<1@3','$2@+$7$A$2D7;(5BBBA!#-,6.#B+
@r2791
CNAAACAGGGGGACACAAANGACACTATTACAAAAGATAAAAGAAAAGATTATTCG
+
#!&DE@#1-H(4G@=7"),$4B-44-);CF!.%=3'5G2A%3H:)91=55D%;A,$
@r2792
TGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAA
+
H!'%2,G88FC$-).)5GG4H/41!E7,C5''/#=7+/"E%:1?:"=%(!8'!=@;0<A%02!
@r2793
NAATNAAGGGAANTTNGTATCCTCGTNTCTAGTTACTTAGATA
+
!)")&$%&)$))"$'%'!'%(%%%$"&+%'+!(&#)(+%(&'(
@r2794
TTGAAANNAANCNNANACGNANTGAGCGNAAGAATCAGCGCACATGGTACNGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGNGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCNGGCAACTAATTCAGTCCAGTNAATATCCTCAATAGGGAATNATAGATGCTTTCCACTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAANCAACTCACTAATGTATGGGAATTGTTTTGATG
+
)'*)$*#%*&%*""%"($"#&')')(++$!*+$"*"++&'(%#$*')$"%")#)(#$#('!")!&#$*%)$("$$*%&"&$&%(&*#*'''*'&&*#*')#&'")(##!""$&'(!")!%#*#*'$*()+'$$!*(''!&'!)$''''*&"##)+'&*#)(#&##(("((!"*#**!+!$$!&)+(#")&!&''(&$))""$+$$$(++($%#(&!&'!)!!$'+)$#+!+#&"#'*+!$')#'"%&%'!+*($#$$$$#*#('**$)%%!+!%(*!&"$)(+&#(!()%'**#%*'$*#*)+%
@r2795
CCGACGATTTTATCCGCCCTNAGCGTACCGTTTATCGTACAGTTTTCTGCTA
+
0F/C37>92A44B,,#8+'0,,@7AB/13$4:H4,!<31+)8$>E$,+C4C'
@r2796
GNGAACTNTGNCTNAGNCNNTANNGGCNNNNCNGNTNANGCAGANAAGNCNACGNCCNCCNNCGCNNNCNNCNCANNNTNNNNNCTNNNANNGANNTTCTGANGCNNCNNNNGNNNNNNTGGCNNCNGNNCNGGGCNNNCTNTNGCNCNNGTTCNNAGNGNNAGNGNTATNGNNAGNACCNATCNTTNNNNANCANNGTCNNNNCANATGNNNCGNNNGNCNCGAGGNNCNTGNCNNAGTNTNTTNGGNNACGCNANTTNNNNTTGNGNCCCTNTCTNNGNCNNNAATNNGGTCNANNTNGTNGNACCAGANCGTCNTAGNTNCAGNANAGNNAGGNGNATNNNTNCGCTGGNNANCCAGTNNAANANAANNTGNTNCNATCCNATCNCCTTCCNA
+
"!#!"#$!!$$#$!##"$#!!$#!!$#$""#"$$!#""!!#"$"!#!$$##$"$!$#!!$#"#"#$#$$!$!!$!!#!#"!!"!#"""##!#!!!"$$!$#$"$##!"!#!"$$"!#!##$!#!####$!#$!$$!!$#"#!$!$$"##""###"!"!!#!"!#!!!"!#!!"!$"!!$!$"$""#""$$#"##"#$""$$!""##!#$$$!"#$"#$$$##!"!#$""#$"#"!"$""""$!#!!"!"$!"#"!$"#$#!$#!#!!!!$!$#!$###"!#"!#$#"$$!!$""!$$$!$!#"$!$!$!!$!$#$##$##"!""$$"$$$$##"""!#$###"$#""!#!"##""#$##"!$"$!$"""#####!#"$##$$$"!#!"$"!$$"!#
@r2797
ATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATNATACGT
+
DD#$H!=0FF"%(9:44(?>4G.-A-?2*87-DG#?4603!C$!6D46?+?@&F%H@=89?-41>"?6,980;?$()$/><
@r2798
TTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTNCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATG
+
*=0&58H&?4=?1-!"H<A)!7E'52"65-G%.-<2G8</)"505@#.:":-E.H'5;,:7%C4+6G(:C>9:&"%D?H550@.5"75C+D;!.50+F36-:<2:<
@r2799
GCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGCCTGTTCTTCGCGTCCGTGAGC
+
CA9#!'(*A%<F>1$CA&(*48A5?E,#&E-6<!%A8%&'CD$;26:);H?$%+)$+6$1%'.!3+#D56>79>7F-9/3
@r2800
CNTAGNNNANNNNANCNNCNNGGANAATATCTNNGCTNNNCGNTNTGGGN
+
"!"$#!#!#$"$!$"$!""!#"#!""$!#"$#!"#$##$!""$!##""#!
@r2801
GGAGATAAAGGTGACCTGCGCANAATGGTCGTCGCGGGTCAGGATGCTGCGNGTTGAGTTCAGCGCAGAGTTTGAACANGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATTAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCGGNGAAATCGACCTGACAGAGGTCGGTGGAGAANGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGAC
+
*+&%"#+'*"%%**'%+'+#+'*'%+&**$*#*$&)%"(+'$$)+&#!+##)#+$%'#*)"$'**(%!#)$((("#!#+#)&('*&&))&&#&$*!%'&*"#+($%%*$!$%('$%&%)''")#+(("&(''+#)')+$*&%&')+#'*#)''$+$("('%*%+#+%$++'!!$+)&*+)'(++$*!$&#'#'%*+$''&%(#*&!))&"!("'"!+('*"*!%!"**$%+$*)'&#("!()')'!$*$%'"+
@r2802
TCAGNCNNTNGGANCGCCTCANNCGCNGCAGACGCAAAAANAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGG
+
#)&)!!)$#")%*$*(((%)*++#&!*"+*%")%)#*!($%%%&"$*!(++)(++%*)+!+&+"*($+!*&'%*)(("!"#"(!)#%)"!$#)'()!#!$%)!
@r2803
GCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATNAGAGCC
+
A&."6,#6$"/45%54;3@#4+989%#"@5;D3<F3*!H1.F?C*+<026G)@/*.#9-;!!("!<)'<#>?
@r2804
ATACCAACGNTATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAACGTTTCAAGTACTAATA
+
8</%A;+56;!%$<&"#)4"+D("5&.%!,E'6%G$70H%EC$8'5/C:(7'&3<1<5?H;B0!<;=8B$G?"A=?67((B15*DCA*G
@r2805
GACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCGGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGCATGA
+
G?#F05F(@E+E#G"3?7A29C"!;<"?1-C9GD78@HH.;>>)%&<<"&50&C3(%@F,(+;2+';D>$E>):#1A>*@C.)+"??*<E;E-G>90'(<FF=>-%5'<;31A9C;25@#/E/+*G(7*@5H/
@r2806
TCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGANCTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTG
+
.%568"'C4?A0/:11)-(,9:1F8=7"D.90G9*24(52$+&&$*-DF%)E5$D$/A1>GG6?A;>8C4*>,AA/FA@!0<).A$?'19>-B&4)1=!C@6:9=@"CH6@!D#!23;38G1%9<@0B&7;$*;!+E/>793$G)*C$%*646!?&C4/*>><;4
@r2807
GCGGTAGGCCAGCGAGGCAGATCTCCNGCCAGGAACTNTTGAGTACGAACGCCAT
+
F@3,.7.82:-@F2<EBG.@%07'E!5&H0/516->6';"4F."?;$+*2=+C49
@r2808
AGGCAATGCCGATGGCGATAGTGGGNATCATGTAGCCGCTTATGCTGGAAAG
+
)A1:B3#/;&$+"3-8G8/+1:?66E-5!5$B4<+'7G;(DFG@4H4!G4>7
@r2809
GAGNCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTNGTAAGGCGNTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGC
+
(#'!+&))%$#+**")'("$+')*((*''*%+"&*(!'(!"$*(!)(##!'+'**%'#$$!&!'%%!*%*)!($+*&#))+&""!*)!&&#()#)$)*$%
@r2810
GGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTCCATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTATCTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCANAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTTTTCCAGCGGCG
+
A'",2.!;!?C(43+HH67%0H%?H2)?3=:ECF*EG<+FE,,=D%.?;FF?E2"B#/'=H/8/>D3&:G=-GFCH:8<4/=70:1F->658(;-,'$$:1!':>A=HCA70@7E:A$=G.%*'+/8+<.0'-)D:A>3H#%=B)A0=!F5AC;.>2<5C))':!?.6=B6'14A&$A9"B)62'G*14:DH;7<GAE3!&+A5C60,A)&C5383+*E-4)>C$(2%F/.4B:-445:50>*-CC6AF:%/DA38!,";4%:2AF'"9B9B7A)-.<0+9H&"D75.+DDA/.8('F.0+?9,859!(638/:FF$!(,$!-B&//@)%H&3><)56!"B;%&&H8G
@r2811
TTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCT
+
/6DE594%0!,9<$<HC2":>%G1;90)#1DB0$>(-0%?$::7@6%?***
@r2812
CGATTNAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACT
+
%&(*+%''(+)%*!(+'("$!!!%$&""#$()'++**!##)%%#+%#%+%%"'&**'*&'&)(#)
@r2813
TACTGGTGCCTTTGCCATNCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAA
+
<)-52.@"3<&.HB-'4HA7B@B9F9*!9/B,7.G"=<*96B#<>"%B(75)??CE-66DE5'B@EC2H;E*@8'"+6#2A>+-G=!>4F0",)%<(3EGH">8)F;8+D&<$F
@r2814
TGATTGCAATCCTGATTGCTGTCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGC
+
B(G<4C<F0+*)551:.<!'"B,?,7B:BDH:>#5E4>-9$H3@-C(C6=DHB#*(+=%+2
@r2815
CCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGGTCACCCTCGCAAACTTGTCACGCTAAACC
+
7/<??29D?C.;*:$<;83)$;A,+C'!.38246<,,:%@(@.#61)1A#5$A?F$:C"<2&$;7$BHC)@/;C1>1&A%=$1,<9;62*.)'(($B?(!9D>9/3'?5.12'3DA(>9?9.5A4D9A15,B3"273
@r2816
GTGCATCGAGTAAGTCGCTTAATGTTCGTAANAAAGCAGAGAGCAATGGTGGATGCAGATGANCCTCTNGTTCATCGA
+
*"D,3'F!A1G-;A.G0)>0G6459%4$G,8H18CC!**-"CBA<4-+AF$+D.4+??:?1,'C-6'H7BB'-=?E#&
@r2817
GGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCC
+
>9(D(/7&*(&?C>7HECCD%1>6(=!?1&=*6-;D"$7F#E<+
@r2818
GAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACNGGTGATGCGCGGCTCCGTGCCGCCAAAGCCG
+
3*D;.>D4'8EG"AF1F+3G?E@=9,4*1:-,B"C"98B.?=1A,.4*(/D57+,36)8<F,<@9@A'4E)7+?CE0A)F878F<0&(<+
@r2819
CCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACCGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAANGCGCCAGCGGCTGATCACCTCCTGCTCCGGAGCGGCGTAACTGTTTCCGNTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGANTCTGCATANCTTCCGCCATCC
+
E22'E+64EGGF9+D,4DA!95<"D2B7)61D:?%/7FH<.@5',F(97(10128D>?<69A6&C$A2'F<"!<47A+GH'3;4A1:#$,/=%A?H>A4*3C?C&"'HG8A+<1/A<%@,:#:;:HB962!59A#H/&4F#,4G?;""@;&1>4?@H3F#B-"22A5:)-"3D)</*A1/F+4)3'#'<$!-C;);G.,C@G046H%#>-3!!3+7!C.G%:=,$<0;5:1E).5$#;%H?/D##(H+#51G?6?&$"$D@23/C(DC0-1?(4@-91,,4.><DD%7>(HD4&9F8"2+=
@r2820
CGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTC
+
):;"DFC%<//7-)6B+)B()-7)(%!C*=88+*2A?9G!DF$FB9;(507$",==-E.<<'(GA$;01B,
@r2821
TTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAG
+
G..8=#?<@<@!&0.4-+H54=8E66,(?.3&!9>#:D'<,D:F*"2?:C=AA+(2DF=+;2274@,05/;?G+'+G-444D6A7>08)3($C5&6"G5C#6$'A++<@1?58""D>
@r2822
GGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGC
+
.@$6.'!.BGG>H3A#>G2=/$8;,B@/7FE-:G=#$+AGG*85F2B-<G8!CH;F:
@r2823
TNNTGGCCCNGTTTGATATGCTGATNCTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCNGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCNTGGCGGTTATCTGAAAATAGCCCGGCGTCAGNTCAATCCTCGANGGTGCT
+
'"!'''&+%'(''!&'***(*"+$!'(")%'+'"$"#+&!!(+##+#%'#($#&&+"+$"&%"+&(%$+")")#'*#&""$+$#!&"#(""""+&#%($#!"&'*&&&")"&&#&(++%)%!*)*#$%%*&"#+'%+("%"#&!!!#$&!%$)(#"&(%)*'#!%"''!$"(+%'++#&&$%**'%("(%)*)%#$%&)")%##!!'+)
@r2824
CCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCC
+
8/B%?*=5D)9;1-8E+FE@4$"/$;;>++,?G0'FG9#);"$87C4GFEB82!)!7$<"5)E03>:F:-!6E=2$:3B6:;1E93@..3-0>5<CD)FEG7AH5!35=DD&C:G'5(/+*G(G'0
@r2825
GTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTAT
+
(*&&'(&+$*%&**$)&'+$!%)*%"%')&#*!')%(*)$")()!+"&$+*&&%&$)*!*'(&&*%+$''($*(*'&'+('#+"'(%!!%!&%+#&%*)%($++&+#'$"$"#&")$("'!#'($"
@r2826
GGAACAGCGCCCAGCCTTTCGGATCGAANACGATGATANTCACCACACCGCTG
+
D0!-@D(?$?$FC"%&B/+D*'A=7H6F)(H5B3408?=/%2E$8(@:'?$2)
@r2827
GTAGGTTTAATCTGTCAGTGCAGAACNCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACNGTATAACCATTTGGCTGTCCAAGCTCC
+
)%:A1&6$7%53F1*9++CE?!4"A:.7!(A+%%%?;(A*&@;;9"'B)4H579CD-+1GB$"88@,-/6)A&<><>09)(@&/A+'>)3AGH>!;A=-@-H=BE,<,"*7?*7C@+>DD;/0-(5%-7CED@);),54@&0.)<*H(#
@r2828
GTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATT
+
F/2A7+HB3'D+)#*D$A;F/.;"/$).<7;H@(A/96!003"$(:52$7,6?9)B/A)$2
@r2829
GGTCAGCACGGCCCGTACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGACCTACAGGCTGACAGTCCGGGCGGTAAATGCG
+
7!/86)+14?9D5DG(F6"79BE:(9"C0!6'4189G9:/.6+83-53<*9F#4E:/;98.&>)38)D<D29""+>?-#3:0H#8D/81,7
@r2830
TNANGNATTCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTA
+
)!&(&%+"!'"'"'+#"&+!)$#"!+$#!)"$"%($%&")&"""*+"(&"+"%++('+%&)*$+""!%(!'!+'+"&!')%
@r2831
AAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGNGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGT
+
9#>'<7ED=.$DE6)CG4,4+&01,!@<6A!F>*,8)7,>(/58/.6?&%2@391:C%FAH/--0>E9<1!?:#",73=(1F:;F16'>)G!52>FG3.")(=;)G+:F@;$'G<1#G.68'6?@?58AB3$D2$!
@r2832
TNGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACA
+
AGG,E%:A/58BF#BA/=5*/3:"<B4%734G'0@*($!&""$'A"5=&;864H=("H?
@r2833
CTTNGGTAAAGNTTNTANGCTCANNCCANANNATNACTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCT
+
)#&##))%()%"()$&$")"*#%"$"*%%%!$*$"#))*'+%*+!%(!)#""%*&&%&&!'(++$()%%&'+'"!&$(*"!()""$)#'#!!%"%(&#'("++%!%*)((*&!")&%'&'")*$+$*)&("+$''&(+!+)
@r2834
CTCTAATTCCGAGCTGGAGACANCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCG
+
5=CG$G<*BA951A2&;A&$H>9*,?F:H1A5FF#DB)%29E*!3!941+H=D!*37D?!&DB$>#(1%1?
@r2835
NGAACAGGTCACTATCAGTCAAAATGAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTNCCTCTGTCATCACGATACTGTGATGCCATGGTGTCNNACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGNCAAAC
+
+G4'>:%99;1B!E>(*'?B,;"=#EGE-%0B8B0HC&?:,5$&B++FE56;50.B@8#&#!5D4//<1/>D!+>7/6F)484><><.H.?C4%/&2'>CB3D2,G<.::@E*+"A*$169@<:D(**=$8G922.B$>@%B*A#$B.+(8"#1,(C=27/'""71)<9
@r2836
TCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACG
+
/0*,/@:('("/2)F9?$@7<=.;HA4E64-5#0H5@DAE1C3*$%2?4HE0*'E
@r2837
CCGACGGCAGGCTTCAATGACCCAGGCTGAGAATTTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGG
+
6&4;@<0">,+:A;5F%BB1(:H<#@7*+!1).2?$;%?6///F#?:(*BC=/*3>?.7(G"3'''88";0</2;A"/%CD+;.:@$B7""G%7,=D
@r2838
GNANTATTGAGTACGAACGCCATCNACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGA
+
$(*&*+$!'*)#%(&"!%(*')$!'"%"#"*+#)*"&"$($#$'!&++**('+$))$""*((#"$&#!(&#+)$%&(("'#)!+%)*#$+"!$%')**+&"'!$)")!(&(!#$!#$(*#"!%
@r2839
CATTGATATATATTTTGACCCTNAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTANAACAATAATGTTATTGAA
+
;339/>*:B-:"%??9G-;G+G;:+,%+:92B*:G$:7E13+;+:#2BF)B5#@8C*,$:B@7BBD(1!D#&3G@F?>@'""!/(6H#G'$>38)<&3&(7<<CD6B0(=%8/3E4).3:3+5@5*G65#/+?:2BF.$()<'=?
@r2840
AATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCAACGCGAAACGGTAACGCTGAT
+
6.4A:'?=&>DE(&6-EC+++C?>=8%1->#*74H"CB0FB*@6<<D6<:?+(0(E4!$$0-2ABB64(,&@B8BAA9(2#44ED#+/1<;;<B)%E9?'!!
@r2841
TCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACG
+
E23/2.3233'G'11:CA=C=A6>&:D::"//8$%"5+-D"2?!1)*E7:(DCF7)=(F+<*6/,%36B&E*7"'$6)H*B168<23#=3#FH"G08$8;,?@7-C:-EE$E7$8+2'#,E(:A"5G:>>?7C
@r2842
ATTTACTCGCGGTNACNNNANTTNCTGCAACCGCAGCAAACTCAC
+
&)'%#(*$*%%'&#%&'&#*%(*$'%"%(%'+#'"&*)$#!#((*
@r2843
TTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTACGTTCCCTTCA
+
A)7C@=BEG%<45F5F%0<:77E:FG%=G*./=!A288;C8/9++4C854-8%9*AD'$>3A>C9!02'A,>",!F"59$7?6+$&'%*;;B=6
@r2844
GCGNTTAATGCCATNAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTNAAAAAGCGTGCTGNTGAAAA
+
'#('$$'$+#!$"(&#$"!##!'&$+!+#'!#(")!+#''$&)+((#)"*++'+#(&)#+&*$!)!*#(#
@r2845
CTGGTTTCTCTCATCTGCTTCTGCCTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTC
+
(F/?.=;=%@&-?>1F+;/3:$<%5!FC1<-+HA.3+E@&%(;3EF@8;AG&?;CA>=59=A:D94?),'3C-$180:.+2G31**A?0+1!'9,:E@E#(#-.#1>4(<:'6%@&"5*D1!)(#%3G'8AH1+:0/H654345(G;C!G=+A@/$:>$%>21B%).11--!%"6E(>=?1E0CF:
@r2846
ACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATA
+
3(<%'=E>HGF!!$>":#/7)2;@C4H#CH'E;-%=9!")E0#%/H-E(A$50(.A/&6<E,6<?+/93?8+4.&3(%*6E@G8D<A1,7&.-H:.&B
@r2847
ACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATG
+
1<1%",6G$%A'+H8;5;/01&+9FC+(-D6BC#&)C5#@B$/0=C*&6!8%<DEG55*@/-8,9
@r2848
ATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGAC
+
3&#&*H8:73%75.=C.F(A?3+$"%/0,C9D3&;4*<>D8B!3@:5/,GD<<.FG&70F"9&$)C=D'G=*-A8>?0=+D64(2,H$<>DD+:
@r2849
GCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCT
+
-0D<)D8F)%"!4@&6?2F!6:11!C/'.,4CE""?CC9A39HH/36%EFB)289=!&9*A*H>G:+@"2B#+<D-A2C*'
@r2850
CCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGTGNCGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTNTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCNCCGTATTGCAGGTTGANATCAACCCGGAGCTTGGACAGCCAAA
+
',<0()F6B,3"90E+31)+5A836<6%0G06,@@$->9H#49?5/=*6AFE9+B8G6A?H51#'0H;@1?:42&.<!%..%0$6?07@C=;9?0D-2@CD+899>4&/DB2#$.>+@+*;>>=/*;@"/"#+4:.-*;8=>B%26/=$%,$CH#$3@2*=6"(77.&=$74639>8D&#(?(,&AG';&</:/5%<)"$
@r2851
TTTNAATGTNGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAA
+
)')"*%&%""+"#)&'(&&""(+&")'*"$))%(!!)&$'&++*%""*$*+$"%"!$"++#"*')&""(+%""#'"%*&$*&*$'%#!&'')'##")!&*((!(%$"$(
@r2852
CCGCACGGGCCGGAGTGACTNTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACA
+
::<;?5+8$--H:F,E$@EB8%/6*3!17";7FAEA!F0?-%1',7?:1A>3!,;>=*
@r2853
CTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCT
+
0@F-G:A'4@4>;6"%?>6/(%G928%+1(GB>!"8>$4*"+*,7-@&E:.=?/+8,.B9F5#71=>#8.;9..535%"711!;4E5:H2@H8#<))-8DH>(4DA>71&-/5;$-#.5'+7?A79!$)48E(&0@$;?CH;.D)#A(2EG!
@r2854
NAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCT
+
$$+$''!%$!$##*)%$(&*$*'*%'"#$)+&+(*!!+!))+!)*$%'*)""&&(%%'+))
@r2855
NGCNNNTNTCNTGTGGGGGAGTANGCTCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGNGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAA
+
%'&!&!&"&&"&)!()##$$($)!#))+')$(+"!(!"!)'++!!#%$#($#'#$"%%&("+("$)!&"+!&&($!(*%!)"&%&$))'++%!)#!+#"*"%'!#$"#)&#&$#%"!+#!)*!)*!#%!%()%#"'"("%+(%'%"+)($&*'+*+&&#))')!*$"()!")%'&&$%$!'+&+!"#*+'&&'+*#*&+'*+!(!*"%*)(%$#()(&*)+(%#$&"!#**)&$)+#!'!!$
@r2856
NAGGGCNCGCTGAATNNNCTNNNACTNCCAGCTCCCTTCGACANATNCGANTTNTTTTGGNNNATANNAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCC
+
'(%&*)!'*%*'$)"#&#$"#!"")*!&()(*#()(&##$%&#"!%)$)%!"&"((#"%*''##('#!+(&+!%%'!!")'*")+"(+!*(#*+"!**'!$%!$'%%&!)#+#""'*%"+!((%!$)**))%(+!$)&#(##)$+**#)&"#*%&)'&*&#')(#')"#!+"!#!"$#)*&+()'++&+'
@r2857
CCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTAGAAGACCATCGGGGTAAAACCGTCTA
+
)+)&*%$)(#%"(+#$&*#)"'#!$%+$('"$#%&'$%(!)')%&&&()+&!&#"'*))!*&*"!+'*!"+"'"$+%+%+")!#(&'*&('+##%'$)$)'#(
@r2858
TCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTT
+
CG>.'G=D-@G4@G4&&8)4("H%G!70G$%!2/&:G:3>'F3</D?4G!?(:*F/A1,3(,-!/(#?7E<AA+=213>"$4&$
@r2859
ATGAGACNCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTCCTGATGTGA
+
F@BGF&%(5+7/:)@"9CF0/'<;F&0$":E3"G2B!>23E6%;CC-')B+/':"=&%;@D8@A+3"/.<+5<D#'2&H4/6)9:8*G9/8=D&?7#?)6$32
@r2860
ACGCCAGCAAATCGAGCAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTT
+
@F,E06-%0,>A=%60-,D5)1GC+C=+3521G.";C/?;86@<.<16%%H#E25$5/.>90F>
@r2861
CAGTTTCCCTACTGTCAGCGCAATATCCTCGTTCTCCNGGTCGCGG
+
A64D8=+816$@H?,4')07'+DB1=&42%:05D*4(E6G2;/!F2
@r2862
GATNNTACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGNTTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGNACATTATCCTGCAGCGTACCGGGATCGATGTCAGAGCTGTCGAACAGGGGNATGATGCGTGGCACAAATTACGNCTCGGCGTCATCATCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGC
+
'#%#"(*&+$#+%"'&+$#+'$#%&+")##!")'%#''+!'&++!%#()'*%#%$'&)"%($%(&*#)%+')$###*!+"$$!)!%%&)+("(#!!$)'!)#+"*((+)!$&#!%*!&#"+$%($!)&$)'*"%*)'*'&)+(+&('%(+*)"*"%**'"$)+!*!!!!%%&"&()#+$"$!""+%"'!+&!+)*!+''$$&("*#'%$')#)&$$"')*#*!#!!)*&($&")(")'$*)%'$#+((#)"##()#(*(($(&%+!("!**'%&+&*"%(%"#"+)"*!$(%+%!#'
@r2863
NCTGCACCACGATCAACCAAAACGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTA
+
")')*+!"#'&()!'#"!!)'(#*&%''!#%%+((("*+'(!($!+)&)")#'*#%$!&$&)'#%)!)'
@r2864
GCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCNCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAG
+
<+"+!4!*G@;%E4H2F:EH*%"&#8D(;/),7'/C3&"&-.;5(:?-$74-7G(%"&>8-,4(??&=#-/C>22:$!@=)3%H7C#/'&1>4&=0%7E/-?-*8(;/BB;BC6:,@&9+&-=@5G63(3<20E7D$#?E=&0+<<&-/G:4:+;A0#%:CH'>;+@;-5"=#E?9.5C1=1&93:;+5
@r2865
CTAATTCCCCAGNGGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTNAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTNGTGAGGTGTTTTTNCTTGA
+
(&%$(%($*%'&%%"+"$()!$))''$%((!($*)*$)#%*!)&!!)&*$#&!)#+(&'+!&'*!%$"'(""*%)&+!&*#$%$+'+"*"#(&!!#'#)!"'#'(#+*&#"#&)&'(&#%)&+)*+)#&"')#)(#$"(#)%(*(#"!
@r2866
TAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTNAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTATCGTCGCTGGCAGCCTCCGGC
+
+(!'&$()(%'$&!'!"&"&*')!&#%&*"+)!&&('&!%%&'"&&"'#!+&"($)!+!$!#+**""(&*")""#*)$')$+&#'+$$+++(&!#*')+&!$#%(!("))(#%
@r2867
AAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTC
+
)%A;)$A!2192!(/+2,AD=<C-+;4*.131#?'+8<$6=(H$=8DB6'?+-7H59.4:+B+C6E/7GGC26$06;B@?!A;#4:6D$5$G:
@r2868
CGTAGTGGGTGGCACACAAAGCTTTGCNCTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGT
+
(B5&4$0>;@26(22=)%&F1(%(::->:H4,DE2%74A%%=244!+0*E<=09@G2@@=@/?!GG44,@!A#0:0A(:@#D8)8A+#B;0$4&!6>D/#>.$D7&HA<%!33'H-=1=";>E4*+@.+A#6B-:'.C@.F+096'F$.#9%26#D/H:/--@477+A.-8<E+(*
@r2869
GCATCNGTTACAGCNCCACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTAT
+
)%#($!('('(!#'"#+#)&'(+))!*""("!%))(+#&%!"+(&#+%))$&*$*#*#('
@r2870
GCTATCAAAAAACTANGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCCATTTCTAAATAT
+
793H#F.220!24F@B$)-+G1'4&949=<AH3D&?&1;980695:+CA:*4"7CC;8-5,B6-+3=?
@r2871
AATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTNATGGAATATNTGTATGCCGACTCTATATCTATAC
+
D@=0"&(<9"9,1E368E"G2)D9$HG<%#"%'AC1B!4=?$B#'@$92')731$1HH)=@H06'->$D2F)CB+*9H0-;?.AG72&79D6="<17!,0.C!<+?A7
@r2872
CCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATC
+
9BE;;6%*80<5/1F7&C2,74<6(+?H?6G6F3<49#<3!1#;2/.7'=@G):CC(B;>+0.$%:.:A*0B,(F'?6,/7D-2=F?'3.#7!(#%,:C@0*2=2:CC'12@@
@r2873
TTANAATNCCTNCNGAAAAGAAAGGAAACGACAGGTGCTGAAAGCNAGGCTTTTTGGNCTCTGTCGTTTCCTTTCNCTNTTTTGGTCCGTGGAATGAACAATGGAAGTC
+
)%'$*)$!))(!&#*&++%%"*'#))(+&&&**)!$"$##!%)*$#)#+#$#(!""&+)$'%+*"''!)**("+!+*%"*'&!*"#*#!!!''(%&%**&"'#&&'#*'
@r2874
NNANGNGGNCAGANNAACCGGAATCGCACTTACGGCCAATGCTTCGT
+
!#*&!%"$(#$&'!")"()(*((&&+())"%%"$!$"$'%&##&#)$
@r2875
TCACCTNNNAAGCTNTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCNGACTCTTGTCATTTGTTTT
+
&*""$*$$()#((!#'&*+)+&&$!&&"(#)&+!$#!+$%+(!&$)#'+#*'$(%('%!#&!+%%*(#&%&++)+&'%'*!+'
@r2876
CTGATGCTGCTGGTGACCCTGATGAGTTCGTGTCCGTACAACTGGNGTAATCATGGCCCTTCGAGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCNCCGCTCGCTGGGTGAACAA
+
6F4,F*@C)/#@&<4/-"(F/(23)+1.,)9G.(3;)(<.1*)',>=19H4;"C1<C4E%/-:42!;10B>!F.@2=)5<4?.E!4B,0#6#12C@@$=##3,(9HAC8@!<7/=>F:0%6G,8$?D>+7B$3AC1%CB
@r2877
CGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACNTGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGA
+
8+&(46=HB*E',6D?<)3.3,C09-6&8H8D>C0->B+:>0FG)E=F$!//*(**<G*A:%694.:BG63.37+;';;#(=-?.%%*D7(#?F41?-"B/>C$(7<:/1.E,6*4((D5.%20E'&3+7<H'@9E=8D+@9<DE>3$D.:'CGD-:D&*$"CCA8'B=.06G!!3
@r2878
NGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCNCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCC
+
!0=<E7!7>'6EHC>8C4@C:#EH&0-0""%8,+*7(-0H);1;,795<&2=4CB8!A&1;F/"/.".2/E*#&?H#F)EAHA9:A*0+&%
@r2879
TCGTCTTTGTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTANTTTCTTTTGTGCAAGTCAGACTAACTTTATTA
+
?B*A"G#A')G>,&)8CF)EB@(!?(7>,-(H8?-=(;G1+?:D?D+E31@3CG3;D*+9A;$D!5)-?''=E6!;3?3F
@r2880
GATACTGCGAGGTGGCTTTGCCCTTAATGGTGATGCCTNTTTCCGTCACCCAGCCACC
+
;809&(7<*E'D6"4<EC(72.37G5&?+3&451$3@.0H2)A#%5,/-E9G?$B?D?
@r2881
CNTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGNCAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATC
+
)#+D)<AF,HE*>="9G,'$@G6C(G6'$)>E%.+-*(6/3.#!(DF6/%'>C4D2-##B#F;($57)!!$;D&"'0$1;F3A-4$>(,$G2&%>;/.+<D(3!FB$B;@9.2+20%H(7BFC/#5#7(60@/'%&BB=>;5A,7$G,@@*(@5%B800&).<F#2-;'953-4)4@?:B7!2/&'6:0'14H%4>>/55#)&$,G:>B+.&9,;?("B'H:E5&".&)?.3HF#6$H.)<'.7D,$?$5?;8
@r2882
GTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAA
+
+1)*+DG#4;,&5F!+1D8.9HBF4>E7@H)>4"7+-<'?%"D%G:-F=-3.09=&#
@r2883
TTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATNAACGGAAGTTCATCTGCTTTATGGGCCAGAGCTTT
+
1@(<-!F6A,"G#'6-?A6D'!#54%#%2&)E($2'!>?#61-%F":22CA+F7#>'678-!<'$5.<<D6!A*H2D3#H#$@C;&3/GB15:/".H(;A51)HEF$*A2;<!DF=
@r2884
ATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTNAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGNCAGCGTTGGTGAA
+
38+E)>*-H=%3%!B"(E(/=!01C16*<1CA"?A1E<5/>0=-#=*'E(;9((9.(7E>2$("B=2"1A=)B;-E(1)&7B>$91-?27?>&C*09%>=<:4@76GCH-(H)F>F$:%?%$HD11!>$>451@C!4<&&:%2?:/B23:CF">*H"BE5241*;31=F/04-EBF38A:;@!B"$B61A@2
@r2885
ACCGGAGCCTATCCAGTCGCAGTTCCCCAAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAG
+
<CH5)"2<3<8./B1<?'%C-#7?:4!54F51CG3&:EEA?:"58-4*G9G&18#E)/85%/2))!9.+<*),"EB,D@7:3.;!CGC<$;,HA?03'%&;A+0EF<FE2%<"%03!3F!3&
@r2886
CGACANGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACANGGTAAACGG
+
7602,@0:(*>2->)3-4(&3B(6?%H*#?4:)D'B,A"A-8,;9AG@?>6+1-?-;9<.2
@r2887
CTGCAAGTGCTCGCAACATTCGCTTATGCGGATNATTGCCGTANTGCCGCGACG
+
*H18(8@H?&))==1#G'57AF3-E2C?2GD?-F*/4(-!32,$11BF5H-,F>
@r2888
GGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGT
+
C>/9895EB4&&@"%'>..+"-:'C1C?3DH);3C!%E<!)"7$,=$0>?EA=EE?7"&<7B@39A5$A
@r2889
GAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGAN
+
8C1%@+7?6,)325(1$(2=>07;E>+/$">.H6732981C9+)?#>:.B/<2(5*:>+*=8,C1F:B-/0=79245?&5-.D>H?*F;8$=>2-@H.;DG%$8(3".@F8HG70B'!733)?/>-$C91:/+B
@r2890
CCGNCTTGGCGTCAGGATNNTNAACCGGTAGANGNNCNGCTG
+
%*$%!&)%%&*$#'')&%##%'!%'$$%!'*$$*(###&$*"
@r2891
AGNATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAGGGAACGTAGTTTTAATCTGTCAGTGCAGAA
+
*(')#)'+")!&*$!#&"$+!%'+**&('+!"(*)%%*#(!*&*&$#"(($*!"(!"+"(!**()%)"#$$)!(*$!*"))!%$$"+&*$+''&*(!!$'"&)(&(*'*%*%"*#$*$(+!(!$&"%)'$&"'*"'''+#&('#")'%)'!$)%+&&$%+*!(&"'&$+*+&$!$(+
@r2892
CGCACTTTATCGTTTTGCATCTTNATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATANTCGATGGACATTAA
+
BA.$>/41A+<*B>!5%6G<8E-HD!B"7'D*78$$!;*7H9H9'BC!';)>'8?-*?F!8B3@<0CFH(;9,($:E)3<G/,B<-"<C4=
@r2893
ATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTC
+
+$D"4D/2B?76,HB?$F5).=)5&50-F77&+/A841=#+C%??-,;;G$1#@
@r2894
GNCCAGGCAAGNNGNATAAGGTTTNGANTNAGCNTNGTCACAGCGNGATATGCTGCGCTTGCTGGAATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTNTGTTTTGGCAATATCAACCGCACGGCCT
+
(&(#)##"!"&(#*"#&(%&%""&*)%))(''*&($*(*#%'%*%)(+++$##'#$+!#!+))&)$&'%!$+(&*$)('(%%$#*&*!&+#)')$!&'"#$'&%'++)'!&"*!!"!!('$*+#+&**+"!)'+$$+'$++**&$%)!*!$%('"!'*$
@r2895
CGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGT
+
H',-;>4%G*7BE6-@;8EHH)3"C"-F,$++1-=9B)HFC/8#%=;6)?6$BG:<A
@r2896
TGCTGAATAAACGCGCCGGGAATACGACGGTTAACCACCACAAGCACGCTGCCCCCACCTTTCNGGGATGAACGCTGCCCCTTTTTACGACGCCTG
+
+(8G*A=$F3&@$>)345,</6?128$*3*=&'E-3?:CDF;@@,4H4&E565AA1C"//%7.H2=$5,:!&@8$$DH=!?+2A:+?H*9#4C)H#
@r2897
NGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCA
+
%+)(*$'"&""'!$)%(!'!$)(+''"&&&&")!')(&!+!$"+))%*)&"$#'+*#)"'*$%+!!#(+(#!!!*%'+++*))'%'+)+"$%%&#&'#()!'
@r2898
NACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGGACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCTCGACAGGCCCGCAGTTATCAGGTGATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGT
+
#+)()!!'+#+*#'$"*%%%+("(("**+%*%#&""%#+&"''#!$!)'("%%%)+!)*#()%"+(#%'*+#%!*&$+++'*')**'*!""$+#"'*'$'$"%"&#&%$&"))$#+"$#)))')+%()*%!(++*%)$$&#%&%&)*)*'"+"(%!$'+$"$))+'+#()***&+("'#*%)*$"%!''$$"")#)"(#)(*)**!*(
@r2899
GAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGA
+
3/"";*$<E/!3G@G+39C""0?3<B9+-9(>$>5D%9A(9>D"365"6+5G3D%CDC92#/!#$>@,9'75DH+B,1B+
@r2900
CGTTTCTGATGATTTTGCTGCATCTTTTGAGGCCACCGCATCTCGTGCTGAAGTNGCGGCCTCTGACGCTTTCGTGG
+
9"/)$5>9?0?8#59;G+=5<+C@1E80/&/-(65$>+8HE>!">HBF1&-:&+#5"+=@7F<)-8H'=?=,;.*64
@r2901
GNAGCGTGTTTTTNATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGANATTATGTACCGAGGAAGAATGTCGC
+
*!+)'$!(!&#("$&$(%')+!)#!'(!!)!&()"+$+$%"%$#('&+%#!'"#$#(%+#(''))$%)')%)+'"*()%+$%"!'$")&+""&!(
@r2902
ATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACATGATGATGCGTTCGTTTCTGAN
+
8.2!1%#"3"!,B$G),=$"*;721*301/A94G1%/5$9&0DE=-9%488B.*F/,;2"HE+A
@r2903
GAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTNCTGGATTAAACAAGCCCAACAANCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCGTCNGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAAAGCGTNGTGTGCAACCAGCACAAAAGCGGAAATCTCGNTCCGTATCGCGTAGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGA
+
?&F=$+.?BEA#.A(947H7:5*:,0CBA1E@%D9-F"@E"+,B(8$!<;B$E@;=$494D</2+A>GCHF3>6D:$,.!7F&4(?C$6AB;ED#A:5C7)'G&$%/16=.=()*:*3/32.EA<AG=.-=1E?);5@5A9)A$<#?BD*(=/?/#D,"<B1/EABF-C+<>>,(,&9><;A::F%+E>6>G$.*.;7%%B8*A0).;10200E-H!9:@G/H7(0H+9:C@+$$@(:C>/A8E/;%$7401"!*21*'&#2!,54!(E*!F$>1<387H5=!@H&H<9<@7'17-!&(>>8&(6>"G@/*<+:&(4)2
@r2904
CACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGNCTTACGGCGTAATTCCG
+
H+8#=1#F26E9)D=@F7?'$,>$1+/("?#'&A&5"2)A5F!!$#D)3$*BG7/14??0
@r2905
AGACATTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTNACTCTTCTGTCGAAGTGATNTTTTTAGGCTTATCTACCAGTTTTAGACGCTCTNTAATATCTTCAGGAATTATTTTANTGTCATATTGTATCATGCTAA
+
"(!(!#%)+)%(')'")+('%'$!($$)#)*!*+++#"&(&%)%)++!!$*'"%&'!*#$+&&%*#*')+*)*+(+)+*'$&"#&+"+%&$#*)(+#+'+#**("%'&)+!##%))"!"&#(*+#$"+"%'$(!*'%"+%#"%%)*(
@r2906
NCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTNACGGAAACAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCC
+
#($"*%"+%%**%')$%))+*#$$!)*)$#*&)$*#"!!!(%"'%&!"*#($+*!"#""#!))&&(''*)!(%%#!$&$$*(+((!%+*")')!&))*"()&+&#!%'&&%$"#$%(&
@r2907
NCGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGNGGCTNAACAGTGCGTGACCAGGNGGGTTGGGTAAGGTTTGGGAGTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATC
+
,))?E9%<!!$/;;$6B1@@!:HH;25D1"@+8E+@0??5"G/@BA>E->/=&$=%74/+5E'%3C9,'+><E;9:",+$94DE'9%4$:?95#=D=@5</!%C)%'3F,D+'=H#=3*.>61BF@$;EAF";B=%9D=)A%5D+9,6H'='&5226>70
@r2908
AAGAATGCCAGTGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCNTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGAC
+
B26H,<;.E-#7.+(A/3-(AB"%:=,E1F16!0'.C/44E96;H;=-G@2@7()!F,:8DB1$H:7/0;6<263#.+C2079@)C.4?!:FF-,8BF!7B?)9(-)/>0<$32)/4/BB=G&7C!=*A16'A@@+'4!,8+
@r2909
ACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCATGATAGTCATATC
+
1B!:6C&1)$&B.G6+C)E3G5G;GG7881F82?9CCD33%">E85E&.&@9$D?>$(D+/;E9#@G8F:"(;("$:E
@r2910
CGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGNAGA
+
)7CA:!<E=-3@96,?#*A50+;B(,H$E=2+H@!$6#/6?H>G0*=F;$
@r2911
TCATTGCANAGATCAAACAACTTGTATTGCATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATAT
+
D489!DC?GEB&BA87:@1GC6/,2@3/(';5<#8+:6)&65F/-5%!$C3F'C&B39(4)=/1117&0#
@r2912
CTGCCACACCGGCAGAGACACGTAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGA
+
/%#;<"=*#!E?@=,HD@>D77=33-5F*<?0"*)@E3E7@"2*G.3(AD@3'C<2@:D(;?&:6A<"$'A)AE
@r2913
NCNACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGAGGATGCTAATANCTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGNGGGCCATCATGANTG
+
"%$C52+2'8!::$GCG$D@<=$0F&>7E#!62G2B!:;>C'/-5;=9E5(-1&(-0.,!)H41B6AC5?879C&>76?64"49:CB><F6':H6#79=!4ADG&=E1=*F*<C'D$006=#"E+!2C=%G=12+0#!+#;H?B,7E"*"%@:;(D>3298F@,<<4<2.=+)H<@E'&CH-F;.HF1%9C:/4-@;5'4-!<*)1=<%,04-5=9$-B+'24+D,&G8.)@&H2'*@&'6,?0;6<4H%$D.=7.H%8?B.C&&3EFC,44F
@r2914
TTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGC
+
AC!8(C>FH9@3-,!5>C.A4%(G")=%:(!(E87,@@&*.-89$?=0@"(@'</#0F,!DB#>34/$1/A+7)H>35!7=$6BD7A"9>2);'@A-:H32-.'8.D>&/-:##H8)2D#3822#;@AB&/;HG'*;>-(<-?ED)4*H(>H#!$<D@")0C8;HG@@E9D*")*<2'$;!9D
@r2915
ACCGGATAGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCNCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCT
+
;688G%;?)><;HF;/>E;>@0=>>"52(8BF,<,/!&?$D++E'HH*?377*1D(&,,14((;>7*6:!BA6@@9B>-H@/7FH"*2/0+49;"/C.5-2!+&/128E(&E(.EC'(46@?E,&;12(G9(A<6(578)G=@:<=H*1GF14*0GD#%@2F
@r2916
ATNTTNTNAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTNGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGT
+
'#!%*&)#'+$!#'$)'%(($)%!%)$'&*'$*$#)!)+(#%(#$#*")+#()%**+&&!")(&)+$"""(&*$!!'#$(*(#!(!)&!(+%"&%*%&*('#)!$!+($()*$*!'+"$!"%#''+#$$&#
@r2917
TGTTTAATTTTCTACACATNCGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTANTCGCTACTGCGCTGGCCCTGCTTATTACA
+
A%A')*;*E#)<9B;!*B32G6$G;(+E'<H1#&-;*.00-#24.'/C#97A>8*<*,..<-;=C/1B."'530,%!>C6+F/1249#)-/&E?0HB?()H$(
@r2918
GGNTAATGCAGCCTCCCCCCGACTGGCAGANACCGCTGAACGGGATTATTTCACCCTCAGAGTGAGGCTGATCACTATGCAAAAACAACTGGAAGGNACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTG
+
((&+"#(()"##$*&&#%#"+$*$%'%')&))&!!$!%%'()"(*'+)#*)"$()*'$*+*%(*!()*%!'%!")"))#$$$%)##!(*')"&#'*++%)+(((+!&#%*#())*!#(*#'#%*)*!+'%#%#"#)$$'')'*+#($)!%'"+&!'"$(''&+$'%'$'
@r2919
TTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCA
+
C&H%G6!B7D88++%(9663D;:>F17=3>F89?#+5+(6C'(,F%)F2+!>'H15+C$
@r2920
TCGTGGTGAGTTGGTCTTCACGAAGGAGGCAACCAGCCGGATT
+
+&*"(#(%!#&%)!%&!("#'''!$')*($$&"!$&$)*&"&%
@r2921
ACTATCTNGNTATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATNAAAAAGCATTGCTTATCAAT
+
'#&&$!)+$+&(&)%$#$)!%(&*&$"#$)%)#!")'"&(!)"*$'''+!'*%&!&#"++&*$%$"((&+$(!!#'&)((")("*&
@r2922
CTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTC
+
B63@D&%87@9#$#0+5G69HG23!<7@7A;#<962%B&++:;5C0C1;G71>;;>@6#C+%#"7'D#@B0-)*3+20/%9$9;7/"
@r2923
CTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTG
+
1H5*+,B+0+61!CD.8*E=-G>G5C$A@+A@*'%/?"G:A.&$B32&<5&A
@r2924
NTGNGGACACAACGAGNAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAA
+
!')+#("*'')!+&$!'!*'*'%')*$"*)*%$+)"$'!'+&))*%$&!((#%$'')&)+"%+)"#+!!&')!(&')+)'("
@r2925
TTGACCCTGCCAGNGCCGNCAGTGTCGCATTCTACGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCNGAGCGCTGCGGCCAGTTCATNCAGCGTATTC
+
?96:46$<5(5.@!8B0.(23)5?*(2<3HC*<G='-F6%14971*/$,>-(0(#8H6?H74(1:45HB"1<>E?/#0$-?&)2)6C.#0F:1'8*)4BFD<-0(;G&D7CC4=7#?8;%-5
@r2926
ATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTNTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTNTCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCNTT
+
-F<);E$6?191=2.(337?*95.15;=%+!:D5.B+;<"F#E$'A"-A6>F%/D",:.$=?"*8:B'=F515D(&<A-#="-@?7<&<:!(*AH-,>!C=/(5#258F?8141CE-DC=G;2/(*$2<'%:=')DBHH0(24(+&("A)?5E=0A9>@17B(2CG"71G2#$*8C
@r2927
TAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCNANC
+
*7&A"7-,=HG1@DEAC,@/.'G83(<8=("F#E&%7<8?+0&601>(%43G6&B>.A+%;>>'68GDA!1F3)7==(+9*8!$,C;2#-ED?E2D#)
@r2928
AGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCAAGCAGAA
+
95(F%B79,H<:AG"A*"366>*4<D%!+C)#.$8HH'1"&"253;,-!9+2@<B7:C(+5E2B(.?8D&D@=D/-CE#9//6C<>B6B6A>96/"&507$;214BEC#%
@r2929
AGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCANAAAAGAAAGCCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTC
+
,@:B=%C0+'E##5178DH7/D61E"D6D(%4.(1#9+D5%&--((C3;BB:<*6C&&3((0#?E@=.C&G)072:0E3#7;(#3>$,>-,B*?%=E>5,%9'+1#7%E,%'<5D**'%B&(7HA@62E/)E#4"+7F>?%95@3/9&9@->D6&0&837!C-!$
@r2930
AATCGGAGTTGAGGTGCCGCNGCAGTTGTCCGGTAATGTCCGGC
+
@,-E%38>:!0(7D'<-5487==.)&F%@4D03-)8>%40?H,2
@r2931
GAGCTATTAGAGCTNATACAGGCATTCGGTACAGANCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTNTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTG
+
(14E4.110&2:+,H;.9"(==67'!;:58)!(=(91@-2$*7:!40/G/D2/1F#2D=,/D1,H'H$*'AG9;FE?;8A1!)46?G81<D6+CG9".@G?A='66&%/FC*8,.4*'H;G$,+7BA+)F5A/F<2>@0E?AE675E$B3C.&''
@r2932
AGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCG
+
B40BH6BA021:-,0>2B1(8",E)B!C(A;=*//8<);1*!HB#F7,/4-@3&%2A,20?=F7D640@DH1@)#6&!84!*HGDF=!0G=>$/$%DA"2);#D8@
@r2933
GTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGT
+
A0'.,.(.@@:$56C<'6(==E679+H%"!5#.H975H;E374+@C.)$&*<*9B414"D(=H*9..2$&A>0%.
@r2934
NGCGATTTAAGCTAAGAAAACGNATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAG
+
#1B8E.4)13/=)<H%&;;6!.01)%C82G##-+BA3#;#+==4&-/=1@-:6E,;;#$?#G)B1+A,?"<;(A8,<*C-14;=E#F68*#G(A),-/:
@r2935
NGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCA
+
/$C-5D:2)7=1*$$,A+@//'""GC.*!C+?!G$C6(<.A(4(>BG+B4=74
@r2936
CGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGANGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTG
+
A?'0FA':;7%5,@4F!5);2F&?58E*C0E1C=59/&-4).8(+8,-(.$"*B>3<4*3->>7!!:"13G3*F)8,4#$0%>='81H#6*@H,,(?5/0'F+*C&.:%F93/009&H=111G281C5B"DH18/22@HBD%CF8$#(6A4?#4-;9H29B"3%6!*G
@r2937
CGTGTCTCCACGCCGCAGCTNCCGCACCTCATCAGTCCGGCCAAACAGGGACGGGCTGGAGCCTTCAACGCGCACCCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCC
+
)C6HDF,6A5.*4E5((!#+!!;AG.8C:6H*516B3*<$$6?!&!:8&4!6FC0E9=!@32:9!?7($57B)D@=F;)+F-<)-*G,C$@?#%49C%!44$1.9C+/('")*GFC1E9<8;8F61:-&/+?/.1/5/@D*+0G!?7<$1B$!#743#1"3-'H6-,5#+(@*%&)'2E19)95(2"*=6#3-0H0G&"+)?B%,'.E<24=@-HE9A8H4)$F2&:6B/6!G.()(G0>0,A30;
@r2938
CNCTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACAT
+
)&'+(+"&("(!)(+*&*))#$#""$#*'#'&$!)+#!*+"&("(*$&$
@r2939
CTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGANGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATT
+
9;&&11(8#A.,GC2>0D)6"#(=E6'/$,05@(3-*3;?:A0;??,='!"17-092&D$#*2FC3()#%@96"A!9-C+66+-E*A%+('9<698H0@/:0F+D0>5CB"9%</?>#:-"#94>GC.0
@r2940
ATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCANATCCGCCGC
+
1D!4;+F>HDD06E?<'93#!<#96>672%52&8A2@H?5$&*-B)5.7))A4'/9'0D3:.;86&7)-7AH'.,5F>7,A"3&&93=A<8$
@r2941
AGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCGCTGCCC
+
?5F0"*6@>/7%+2!5<0'A8F?B35?*C-%5GD(>:B6#)0(?,=336@';%H;4:/)HF9##&2.@%H:>G7!+++@.
@r2942
CCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGNGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCNGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTA
+
84(!)"&*G>">?A43DG3,>5E@/HD"C%BD"2*;9G#*"D"22!@CCHE179'3GF1&$B/(<E>A%%B99G1/A6.=4++3/%6"0:/-$',+4$!*,>4,$/;,/%B%4D4#*+/,E>=#)&2"8.($7,@G.-(
@r2943
ATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTAC
+
9-)B7)0.!FF).E-*,7?G'*#95"D4,ACG?$)-%-$<H@?7&H/H!=AA=<%
@r2944
GAAAATTAANGGAAAATCGATTCCTCTTATCTAGTTNCTTAGATATTGGCCTTGGCTTTATCTCAATATTNTATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAA
+
2A6C&35)%)H##*),2F#96FG79!B!85;8C09+!B.7*&.786#2A$-&-$$E&:47)+C6..0(H-2$)<EDC9,21/.B?,G3?>%$:+8D;:8=>5<5'/0A$<1$G;$./
@r2945
CAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGNGCTGAAGCTGCCGCCGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGC
+
$D:5BDB9@E94EFF"&6CB'4$06(<G>3#G8%%9/'>02E7>358B1GDG1%@D.9G8)F7*#:?&!$(3<7.<<@<:!H?<;B7>EC"$15(+="0B*"=!E6AH3>H3(B(0)3B.$?<=C<0-"@?0#5(&=?5+&'/,
@r2946
TTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAANTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCT
+
/5F,&2#*82@7%0%DBAE(4?-E@A53D'8:7*A51:0(5G@;??2?;4A"150E,+D/,D('CHH.(#H*,@FC1DD5"/-05)%+*3H9-5>7+E:C1;?:G.84C(4>A&1F8052!
@r2947
CNCCNNTNCGNANATNCNNGCTCTCTGCGNAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTNTTCGCATCACTTTCCGTACNAGAAAAATGACGCCTGACTCTGGCC
+
&!"*"$"&&!$(&!"')#%))'")((%#$*&+"#$+""#'#$*%&'!$&#*#&*+*)*&!%&%)%*"$(&*)#&*#'+"!!"%#*%%'+%$!%"(*%($)+'%#""#$''*&#!*)#((('*#$
@r2948
GCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAG
+
E2+)3*/>--,.*HDB'.A*0&,<5@$,)5>ABG./H695"DE":B+=(=.EC21=>97AHH#)F"(C7>9)$*'':7522$H1%6'65133DA%$4:B?,":85@-23+5=?A3#'
@r2949
GTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCC
+
&<DF8B=#8A3'4%E&00;=9=#6,9@)*B28D00"#HH*%:=7$0;/BH"?E41:?FAH7E-:D!
@r2950
TCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTC
+
$+1'F.HG%$>F;<G%5-,0E">(B</C6-8#&*$&*59924*5F)C-?@97G%96281.#;1&(*#.5*4$%)%#8&+.0
@r2951
ATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGANTGATAGTGACCTGNTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATNATATAAATATCNATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACA
+
7H39)4-"HCB+%=%=;:1(G%B3:+73-:%35'83<A$)*H94+%G>0?!?6C*:1?H95;26&F7A:/)A7;!(-%&F$=<6G"4;4AF/%4?-+*+-<8H%0>0,HBH+,82F1=7*!@!F>(7><'E/1;)8?&E!,2#C9+(#/EC>6;30#")8'6G64-B$'F;2"E89C&-/#A@-7-'!%?59D+725*D(A26=1<$C%*"HE6C2
@r2952
TGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCC
+
$+*'(+%+#'+#!(()'+*)*+%(++)$'%'!#('"&&!'%(*(#'*$)#+(!'($"%))'('(")'*"+"$+$*&
@r2953
GACGNANATGGNGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAA
+
''*(!)$!)$+&"*""$(+&+&*""!(#''*&&%%!!!%)#("""%'*")"!&"%%'%*#!!
@r2954
CCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTG
+
8@-)?H=@87?##//!6&69<!23&6C;2>F45A$>7=@CB(B14F6E.>!+E0$#.3@H
@r2955
NTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGNCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACT
+
"*F/@?+,2F02&;<D.47C,%B),+4E4#(=E4&++*-);(":3%F5;HC4BA5,0D+<#=5,.:4$$93)>(,.)$;H0%,D,5@%=%8*8#,6(-H'+'B8*F>?@%?>=?-<5>2E%'"#0$-8/&?03*H@E0"(@8F55.#8%D&!1:C.>/C.7?;?@EG:*$H:G2$#C#G:H0A/;#G%-/3%#:BD2&!C96?
@r2956
TGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCCTACATGGCCCAGGTGCAGTANAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAA
+
"=+2F:F1>9DF(??76!,<$D#-**(%,E'!@CE"/E*;D;C)1D%E9F9G2)31C&8@5;G?'"FE2+F=@?59<8.E+.1B6$E4%!@D:D8G$*.0A*%1!9:*8H1@0.&BF<:$F1+7<A;=D="+!B*3,8"6134B;!/9)2(?6
@r2957
TNGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCAATATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATANTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCA
+
"#BE?9$F-0#"/CA/@B''7&$$$!ED.>6HBA1GE(3$"A,86#HF0@7#?$4:#3!B:7;8&1B;>E#&3#?HG4508<7,DAC.!;H,4*>B&7%#9)=:".#'8!*2$65=;??7!E+(;(4-<%:-812
@r2958
ATTATTGTTATACCAAATGTCATNTCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTT
+
2&'H;!=<+!04GEF)?;(%!@>799"C9$E-)+6,=CA(#8)-&:37EH,B'-=0!!5#&414
@r2959
ATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGA
+
A$(<F-7F.%621(36C9-=+8#0C@CA%E+4#?%'?B?*2,B--2"FA<#2.%:5:7&<=+4,/#"%9+?H528F1+
@r2960
CTGCCCGTTACCCGAAAANCTGGGTCACCACCGGCGATCCGNCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGATGAGTNCGTGTCCGTACAACTGGCG
+
,*);H1&.<6H=788,F8!B)38B'9?8!;E1*@G*86E(?D1?F=&?!A>*>13"A4:2;2")%6E<*@'H(-=E9$17"!->4G=D,-DF,C051<C$6H2/((:BBDB#9)C*3*0//
@r2961
CATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTNAGGATAATGTGCAATAGGAAG
+
-*+-B!'/90/12@G4:B8$=1!#@F0.?#E?6ADC>'3/:D%@-.C"=)'#9!'@4+83$6C*8#*3!=+?-B4
@r2962
TGCTNTAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATG
+
*)%$#"+'%&*'&*!&$!&()+'*%!*')*)!'$$)%&"*"$
@r2963
AACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACCGAGGATAACGCCAGCAG
+
C)'CGC0-'!.;>HF.06?*#:D%;8(B@4*"=+G7B?0E;*&@8=3"6""8<@7D<:?G?::B5%
@r2964
TTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCT
+
;<'G3CG2<G;3D,?("8F<#73$1:"&7/9#;*$1>@@/;E!?F(.(E!2+,8<41!3!8@:'@689@7@(:<?B6+#3G((4!
@r2965
TCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGNGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTCT
+
**&%+$&&###&&'%+!#!(""!++%$#&+(#+%"(*"&$#+%)$)"&%&%"")$'(("+)*"+)*("#%$%+""%#*"%#*'')'!!"%&))+)*&#+&"*%'")($*'$++$'"%#&!+"&+++%')"$
@r2966
TCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAANATTGTGGGACAGCAAAAAGCGAC
+
77AH>9-0%/;308D(809&$&01"('*F62CG;)>-,>40-F??E=7:5";'=<+5,@D)666C1G$D5F>5>7'0G+D.&+H8=,!5=A">AC-F98)B-D%#E6=)'=E21+);
@r2967
TGTTCAGCAGCACGCTTTTTAAGCCATCCANCGGACCTTCAATCGGCCCTTCGCTGATGGCAA
+
1?,6*04#C:@'%5H'!@>:$1F6%76)=,(($!?/$>2F<B$'=;;+641F620$98+6$@&
@r2968
CAACCTGCAGGATGACACTGTANTGACCGTACTCCACATCCATGCTGTAANGCCCGGCTTCATCNGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCT
+
)*&+!('+#")*%+&&&!)!%+"$##%$)%$%#*+&"+($(&+*&"$&'+&"!#(+#(%'+&*(""%&+#!"*%'+')!("('+$)$!&!$)"*&))#")!%('')"($++%"+)(*#$)&%!#%(('*+&')'&$'((%&&!"+'#)")(!#%+$#+'!%&')
@r2969
ATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTT
+
/,.@#FD-,:H&-;-@1.H@30+'>3;0"(=?"@295&"=+B
@r2970
ATTAATCTGTATACCTGNACTCCACGCCACTGAGGTATTCCGCATTNCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCA
+
@/*0;56A'HF&5=G*EEA&G1.=A3E4$CF!'-2@#22D>?;,/"!*!A)(B'/=+7=2/990)F!F,G/314#)5&H;
@r2971
GTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGTCGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATNTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCC
+
B6.**(B.E0A9F$')GCG*6++69GD5#4$%+#89>"H-1;H@#*'=AF,CFH$><;2(%DHC7/<BC@D5/)D-=<B!=##B2"<?,!,H1":>/2,$FE'/9$.E"9*-849$'!D@'F+!&"@7*@FC=+>#8;@?&'F7A-#H=%
@r2972
GTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTG
+
7G%/$%E60'3<$9,=&A2FA:1*$D%&*>G7=!8/@/C3(!B'#0?/$-<)0D/4(7@!/
@r2973
AATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTNACAGTCACTCCGGCCCGTGCGGAAGGTGGACAT
+
+''##!)%$!'"%&%&''("'!!+&++%$$(*"!$)'+$+)!'(&#%#)*('+$"*)!'+&+""$+(&"!#$+%#
@r2974
AGCANGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGANAAATGGCTACGAAGTCCCTGGCTATCTATCGGCTTATTAGTACTTGAAACGNTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATNAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAA
+
!$"&&*+#$#!%*&%"'&&'"&%!!#$'**$#'*$$#)&#&('+**'!+++$(("&$+%#%'+'#%(('"*+%%)+!))+"!!**()+%%$*+"*''+'%!*!&))!&***#((%+#$$+(+#*($"+"&$(('$)+***&%"#%'&##%)(&!'*(!##+)!'+("&'%)+*#+"$(*$$#$%(%)##'("&)&+&'!+&''%$!!&'%#$)#"*&%(%)%#+%*)&)(#+(!%%)'+)#(#()#&%)%(!*'+"+*
@r2975
ACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATT
+
,/68;-$&A2?%<HHE55>G;3G=C'/,E>*-+$H*'85(;@704H;G5@H;8%?26'.=5@A:0B4
@r2976
TGANCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGA
+
(("!#%&+$"$'"%!$%#(*%'+&$!$)#"##)!*")$"#*&%(!+"!+%%!
@r2977
AACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTTTTTATGGAAAAATAAATAGATACAACTCACTAANCATAGCAATTCAGATCTCTCACCTACCANACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATANCCATCTGCGGTGATANATTATCTCTGGCGGTGTTGACATAAATACCACTGGNGGTGATACTGAGCACATCA
+
DBG$#:(%64:?+9!9:%B/&7!8!GF*275$9B.B;%7C"5E%F=+6$EBC+$!+3+0GF<#9)!4.HAB''2*A#%.B>E&%'.$@D?/$F35>3*74/+?,=D/4A!-'+7$G#3HA*$&53%5BBF,0E,FH67G=$%B.C7H!9'0C")441'6,H,B=88G&;-+(,;G!!"(5EC!/;F)":2)(()!C<'C2&<8C7?<(!F-'4@A80)#>87*$@9E&&<H4*7EHE=A<(G:2A605
@r2978
TTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGAGT
+
6!,E%>GD6E?9>4"A-EA/CD>>&3(.F.5EF/<EDG9?6(>D,>7*7/=#/7.C#)1&3>1A7GA*H?3%6H3@="(?A)@G#CC6F49#B0A/0
@r2979
CCTAAACGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACAATTCTGAGATG
+
@:H+C"::>),$"#/=!:"2@51($+%$DG.$0C>/>?&>%692*5!89!,:?HBF)
@r2980
GTGGATATGGGCCGCNGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCCCGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTTGATCCGAAAGGCTGGGCGCTGTNCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTG
+
6.79/2.HD1H:.@+/&8(@B:&02>/.#(F?F=&FFC(6%BFC..6G%@*H-(5;B3CC"05C.*;#H?8C%5:'+?C1>58,#A/+(DB6F"#AH<CA3A-<EC,1=1'-$E%A-EE8#.9/:;1C!E:?!74EAE6,+G<7:4:6B)'+06D%5%//65<@';*A"/7&$()F1;?3#C/0E,"'BBA.3.!&*>-54>A<<"6FA(CD08,3B$<%?68BG)EA5FB'(!>"AH+892=%C/%'6@3+38+)8:$?(#E:9%,82856;74!!25=1':%F8C0.;$'9-;??A*'F.G.F*1-&C"/;,$/FC;HG
@r2981
TGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAANATAAATAGATACAANTCACTAAACATANCAATTCAGATCTCT
+
0<B6..?7?#>)@*&<*%H(:89%#0>9F1!<A>CD!'3%5H>>$(?>*&CC@3H3BG!=+:B<D(7;E7H771H:9A8.")38/B-@,.(
@r2982
CGTGTGGCGAGACNGCGACGAAGTATCACCGACATAATCNGCGAAAACTGCNAATACCTTCCAACGAAACGCACCAGAAATAACCCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATTCGGTGGCTAAGACGTCGTGCGAGGAAAACAAAGTGATNGACCAAAATCGAAGTTACGAACAAGAAAGCGTCG
+
A5.#4>?-F@F&:<E(B.@%)@H$.%(=0)&8GHEE83*!&C+A&1/FH&G/%GA/;9"47-),A0%*!'11D"<$7B$;73F';G3,@E*E<0<2/9!=64:D4!@@?+E?"9.>E6#$AEDFD/(GF-F?H98A8E>G6E/"=(06>2.?0=-);:<6D?9DFF+B)>+?C0@C1<$3'D968$2=<857:@C?:D.H7819)H@C%8<'*-=+3*'")%
@r2983
ACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGNGAAAATTCCCCTAATTCGATGAA
+
H;FG1:09=(:25326&9$)?HCB;%:)-,3C/C384)1638)6DG90)@H0+8%6,;*:%)6&><H=398!0;#:$@%6F(@)4#/3(%!)%8"@/FE-+<%D1(5H)(#55&47:9B-*4A#B'-1'H0)?)0&5*9&?8)$(%/>3=,CH)C<?)C$E43FD+*,7G
@r2984
NCAAAGANGNGNATGNATNTANGAATGNACGATGCAGAGGCAAT
+
%##&%&!$&!%"))#$)(##(#&#+&+(&%*+"+%'&#!!)%&&
@r2985
CGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAG
+
+3.,%43G+=F:;DF"9&*!1G?"@B8B=$013'&95.59.,#
@r2986
NTANGGGGATTTNCAAAGATTTGGTCGCCGCATCGACCTTC
+
'5B)0(5CGCCD3G(4?*D*";:FBF?B'(!8G=#;*0%A2
@r2987
TCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCTTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCNCCTGCTCTCCGG
+
,'E/:D<E'%,DH/%3>?D>D5A2A2<41"GBGC/HE?&C4+!#%%>CD?9%:7HA.,50B6A.55GHB!,B1/,,:151/24@$D75F?#75!BC>2#AE89/C'88$3G7C9G#>>26DF9DA!:B-EG(F$G1,;5B7='>024'0=;H?2:&=(=!+7
@r2988
NANNTCATTNGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCNAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTNTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTG
+
!(#$(&)&"#(+((%%&$(*""*#!*%($++(+)")$)*&#"%%'""()%(*)"$$(&"%+&'())$$$'#+*)(*+$%%##*#(!!'+$*%%%!#'$#!$#*(+))$&#)($!&+&("&'%**$)!*$"*!*"'+!&"#($"'*)+%$*(&%!#"$)$
@r2989
GTCGTGGAGGCCGTCGGTCGGGCGAGNGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCNAT
+
"+()"(%&"!%"!##!$"&#&)!$!)#!%#'%+&!'&(#+%#*)+%$+*$*+)$##)+"%&!!+('()")**)(%+#$**&
@r2990
CGGNCNTTCNTTTACGGGGATTTACAACGATTTGNTCGCCGCATCGACCTTCGTGTGAAA
+
"(($%"'"'+++!!$'*"+%(*'!##+*"#"##")!+'+"(+"(!$*$**!"(%'"**(*
@r2991
TAGCTTCTGACCGGAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACC
+
#;F1&5E"5&?:?9H"7A$'!#DG$?E;?356=+*@#D-E+4'&45@554<>?@3E@4B!/B!+58'=G2.+%,#!,?F
@r2992
CCCGGAGNTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGNCGCGAATGCCTGTNCT
+
+@=A#F-$-=(B(/97.2./=:D<-4$5@5+5,0$+2(@=0)C=F3'G1H->$(!>-@*%'=>7?D%+'H*G
@r2993
GATGCGGCACANANCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCG
+
';+;6@#E@9);+E<E)5A6*-)C1:AH;@H&./9E.,1%2"518!;#-==$>*1<D#;A1B@>6.B#&8A*C54?,3)%A+H>::
@r2994
CCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCGTGTCCATTTCTGCGGCATCCAGCCANGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCANGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACCGTGTCCGGAAAAGCCGCGACGAACTGGTATCCC
+
=$'H%2,05%,"&F!>CB(E7/63*4,.0>;74%G03EE30$,<!1>'1>3+*+&99D&:(2$.?56G>8.73-2&H4&7#.0!";">7"G,'E3!*/#(G1'#5%$B2&;AG$>EC9#D+=!:F4A%.3<8//">)%-+=,?+B:*541!=7D7$8$!+:+@;%!E$*<F@@C@F.F+;:<#9?B:'%/%B&,'0?A%@7=F289AD03F6"92B,50>B:9FA(!6%!5,F#=*>"9A!8!HG&.*)6)(>-6CC>(6
@r2995
ATTTCGCGGGCGATATTTTCACAGCTATTTCAGNANTTCAGCCATGA
+
+F219=;,A1D(8'"E">06(DH<2H-;'(79CF%6<AC8+47>7;C
@r2996
CGAAGAGTGCAAGNCGATCAAGGCACAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGNCCTGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCNCGGTACNGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGAGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATANTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACANAAAAGACCTGCTTATCTCGGTGGGCNATTTGGTTGATNGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAG
+
5<11+$25>'1(+=E8C<<C$%/=2!;!:DB2#2-,DEB!=H.!E=71C<=DE&E/0A1'D9'=&(8;<7!A6%;H$:E%:D899$D#H<*#*+B'H,BA<E2F!8=?@%/4A+$;<21+6#6$9(!0&)!*-'G54#+3&(/B/*&8:A42B,C(9H",4?D.:F0"5'B8G!HDEGBD#*;F92!A/56*G@<+A(4$%!5:%<.9'1!(+0G((1?F?+4,>08'9+D$DCA?5EB5F$?-,A/1A>=$1B.)*A3;*--'E*A.0GF'0C6?,3-932HB!H#D=;4G-)3'+<&5?'CF>)*D4-FF%7@03.$2.HC>"9=H2/5@.AA&,<F31E/=4)B//H35"97!88#>1''/;B#+E>6(C+102;E>)@95#+%A98!/869<:4>8C?#-A<?0>+#(!,2HAF18"5>%,&/=/!*&E7B-2F.G.7D3@:'BA,77H;%4+C"/'26;G#.=
@r2997
CGATGATGNCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATC
+
#B$3D<@)->C1H0,>F=/)E:283D=!2(0$@<0<"54@>=,H=31'A2/G$4=@B;D.(/2!D:-=%'!5=G3<&?H96<(E!=277,#2&5122++#B*:'-H/2'E)=DCD"97A#10,74@*6%&*2E
@r2998
GTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTATCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCNTAAGCGGCTACATGATACCCACTATCGCCATCGGNATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGA
+
B/,%%8?&8:'3AB8%9=%=#257C(D1!%2.#'$)5?#01B&%84:E:2D+2?9556.1$<H;?!(;"C(;."!$@AFA+!0<H>>B60.;C;DHG"#A4><):;B+=(B%.&3@12<#'?BA).E*%,:*241$>"0(F7(7<?6A(2H,'4$0"4!'/C<@+@/()75F1*7&0:8:,--$E@>=B&1'40GE"E/D)B?-?#8C%,&0(1=)>GA3GBE(!,=;.*;)9-(G.G"!<1B$:.2(<&?48B,3-<G(@>,AAD2E65(5$8!E"3.A?#*)-*,0:@"D2C1')(?H7.D2:1F/+0C-4;#)622*.$G?%4/A.94<A)DC/BE($,@:DF@3;41F!"&=2!CA2#2F7#DHC
@r2999
AAAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTT
+
).?:.F>>(D*B;!=/.B/1@-G0);-..>A+$4++H?@@F@0C"
@r3000
TGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCCTGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTNCGTCC
+
%@<2C<0-$<$D*#:*"*='0)"72C*=49!#'(-)966?%(1?='5&;@#.-6=G.H9"A:0'$-HA*4)A@73&112$),0:84?=33G4GH0@'(89H!$
@r3001
GTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCAGGACACAGACAGAATCAGCGATNCTGGCGCNCGCCCGGGGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGNACGCCGGAGAGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGT
+
2-=B9+*&4794>#;/62;7A'+5'$=G%#)E#C!)C44+!>:4E(@42H(1.#&$'*(!(H1*.;-*&A/+D14A2F5%0%C5>+,*BD3H?,$21H%-.C0<D.)'85'*2*:'H379#1F5@,#!,%@9*>/)G170!#'8.E'-7(8<!(&H9E3<9C52$!"!-:1-3/BH./3,?G&,C24:BE>AH>.,
@r3002
TTCTGCTTACCGTTATCCGTTGTCTGTANACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTNAAGAATGATCCGGCAATG
+
6'8!FG68,(4)3/F)6%1E-H0&H2#3)H?&!/-;-64=-6B.A3FA<4=:H95AAC+#<4'9$GE247*#;C;*1"2H!>E&.)F)E&BC:-<#)F:-HA;<5<@(,"D-*95@%!B0,C+*%/"",2D"=:CG?7E9H$&'BH<GC,$4FF3B/B$G%-H807&)>GE0;2)+A.566-6$1B
@r3003
NCTGCANACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGA
+
(6F-<E153+@GH)7-1!&A=2).$.?F/H</*4G7H8HD*"'*@%44FD0$$>88=B);7
@r3004
ACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGG
+
H*<:"-84&#;ACE!2.6'BH@!!F<H;#=/DCGG<4-0GC)F)7!$<'?6:;8">/!C?2G4?80D7=/3.)9!;:4+),-CD9?D9F
@r3005
TACCGGTTCAGCCATACCGGACTNCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCATCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAG
+
.5"D16-11D*5)>B=AB6DH*(.%(A/-EC7("$D@,*F&;5!84&;9B?2+9-3!;-+5#%3<9/:&"-;3.HE<'5(;G:7/F+5B&376C2BH>A4."*,H04&H+;'&+(BF51%@H'@E?%*;,<+C$?%$*4+602<F>:%1B(CGG6*:'46C:)B7?'$8.0/>EE=A*0;?7%."@*5F8(B
@r3006
GGCGAGAAATGACTGATACCGTGCAAATTTTTTATCAAGAGTACGGTGGA
+
!%$"+*%*)%+!$$"'($&'*+!#&%+*)%(&!#%*""&)*)#++%'$+'
@r3007
GGTTCCCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCNTCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGANTG
+
:@4AG1?&'<,?>7=7H'.F!%39+.00;!60C4/;EC(3;2$D>*6F48=2&.1>*H)B-5>AG?%/&@#DFCD(6H9?8;1/$@BD-2:E0HH1.'BFF#/*.H),>D/)8C#E4!H
@r3008
GAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTNGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGCACGAAATCCTTCGCCAGTGGGTNCT
+
+5,C/<,CD%1F(<$H%=*G$%&39=3-B*45,7>>9H#(=@+35F,)B@86H8=+.;AG-,FD-?=G1E*>)D%G/02%%AF*0.'A&)#$F0D965!7&+B@(/..G#<2B!%-E5.H8!D-HE4,&H:
@r3009
AAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGC
+
><,BB2$;?!D%="AD@:77!H1G",+#B69/*E5D60";*.>(1G+6CE@)*(3E)6+5,//,24@$89F6=&ACB-*D#*"*?E'"F5>$C=2H0%GF6H:DED5)H'=81
@r3010
TGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAACGNTTTGTGTAGTGTTCTGAATGCNCTCAGTAAATAGTAATGAATTNTCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGA
+
$:">FH/73#3+F$#=H$436D-0H%2,8<<3%.!".E:EB(;@H7C(A3-G:?G6&%%-!%1-<%@9<$/HD>"!H($1A5;?&B1G6.!*D&>1.*9/<+4?(@3H"D'0.!"%,@3*B&;B&A.!(B5<=>0*3/.1D*+A6>0</+#3BE(5--HAG:&2-.9E7-&5:D91
@r3011
ATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGNGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGNCAAGCGCCCNTACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGC
+
>G+CD.F#.:#(,3;+=(78:A,&'$2EC"*)<@?-E&BG,)H#/'!C'.1$&,%C:$5;"F?$)>A95"-,'4D@;814'+D#=F>3003%%CH;=)9=57'(#/:!0F!;=@1H?:F->0G0FG-28&B=?B*,5:G*+#><@<$1'18E1?E4**-+B@15!*=;*?'1/22'H<35&@1ED=7D-G=A,4#-7DC<!<0/(E)CD"?4)6;/*88",)$#;782+10"D')@<.%=6F8ADD7&>G8>4*:@')H;)@0<A"5A?<@F>E)!H>4H>#,,8"@<$;&F?2;G4==(5*.24B),FC#22@)4;=>>=G.?(
@r3012
CGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACNGAAAGGCCGNGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTT
+
=CE2(9:2&#<8C0)!/#B7%)3!>)D-EDGH0;->0$"2*"<9)<;=F.$?88='%&/;)0)(6<:(9@A='44(38FG2-:1*HF$@:A&D&&@A7%-?%%A<D0(&6G!@*:4;AD75F!%</A1-42@A:E2A2D6E/@'G<.!7;,-A%2<!%?83>41@&(@(B*)8&162C@==1@82G;>+*!"6?8$(F)1$%H619AE/D"67$CH(A:02,=++C8-1.B*=C"F:5C'*
@r3013
TGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCT
+
$F(#&)<=?/F$27C<4.!)/2-=G3<6F(+4+1.=2@5%GE@85!2B0<7-;
@r3014
CTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAG
+
G;;)A13+:6+-@BE%9E:;1>@8,C(%$)C%&6(95:(:1A("'*'C("@71!."H)1DH$$.82EB8#,@?+*.BAA
@r3015
GNCCACGCACTGACCNNNATNNGTCATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCANCTGACTGCTNACCGGATGTAATGNTGGCTGACGTTCCCATGTACCCGC
+
'&&*"'$*'&'(#"&%&')$")!+(!$$&!***)!%**""!"*+(*#)$$%)%#(%""*#%")&!#*#")'##))!%''&*!!!%!'%(#"!)$!!%&#!$'$$(#+(&)&"'
@r3016
ATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCG
+
B$/:7A,/A62#+6EB:>,E5,A;*$EG'!%"(."HB?CE
@r3017
GCGATGCGCTGTGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAATAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCG
+
(B3G<0/71@2$98+DB6;,AG#5B%+.'@%.:/*E"H.H$#CA<#?6'03"996:8,C6D2$9--F.0$!";/-0H')D&)-<7#8%(59*6D5FF#0)-8-/<A>,;)HG.-@#F@43;F!
@r3018
TCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCNCGCTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATNGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCNGCACATGCAGCTTCTGACCGCAGTT
+
4<8FD=)'->,"8;D4>@<0#'*/<;38/*A*#/&BG7>A>ABFE"+,:..29H,CB<$>%@;8451*4(8?%(9.,%A;3/8&=HCG>F(*C(?:%05>/A',8:DC-9G55=)#*E6((<A+D*AB)%D6:%*(.C.FB0<2?'+;C#;<"6*:G&<5,;1+1D@$*!)G413@4C;7$-@?D'$G>!2+3$,!5'>8)?D,,!H<F30AB,($A8*4'H!G(1;=;AH*@F<,<H<HG?%*&9$2*1-0>/(;+70?)229(78F8B=,@'/<-8!ED:C'C+4"("GE;C(=:
@r3019
NAACGGCTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCNCCA
+
%(*&%'"$+!)$"!!(#$!"%$#+%*))$!%(#%#(&$*)*'+#!%('*%("%#%)+&'&%!')&'$&'*"+$'+"'%)*##%#'+'*"%
@r3020
NGTCGTATGCAGGAACGTGCTGCGGCTNGCTGGTGAACTTCCGA
+
#F:"BGF$;(20&B1@9>';*6>6%$*5H;($H(5'&+F'(:H%
@r3021
ATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTT
+
.,(@,:?D.@$)E;B9199H(E>)918G$!'G&BB?C!7#.98.6C1?%E%FA)8>"6'A0:
@r3022
ATGTGGTGANTAGCANCGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTG
+
+!%*$#&%")$&"%*#)+)#+$'&%(&!$+*&!&#!!*+!+((+$""'$#%'#
@r3023
AGAAATAGAAGAANTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCCGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGACGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCNG
+
)%'*+*!)""#&''!!%$'%+")""*$*%$+"$+*$)%(&!*'#+#&'$)')+))'!*+$&*#"+&)*)&%&!%'++"$*!&(($%+'""&"&%"(!%"#"(!#%*&#$#)%%$"%'"&'*#)*('&+$"#$+"#&(%'%$%('#+!#+#'#*(*""(+'$'"%&%&)")*)$+)
@r3024
GCTTTTGGAGTAATCTTTTAATCTTAAATAAGTTATTCTCCTGGCTTCATGAAATAAAGAGTCGAATGATGTTGGCG
+
1GB=G5"*+952!:>'BAD<76-4(D/5)51(*>02%G(*8G)7:!?E#/&8"?A+:3<FE2-9#D%2G6!.(""4A
@r3025
GGCCACGGCTTCTGACTCTCTTTCCGGTACTGACGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCA
+
+=1!F*68B9:3+:B(.4C!2)78F<GF8HE$;4623G34GC.-/$"<0C3?@0*!2+@/&A2C"'@D1H41G/+6<6%H073"$.2/!26))G@)"!F4C8'&%+)*2"6&0D
@r3026
GTCTTCCGGCGACATNCGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACC
+
<+H:0973#<3;*.;#H,<4//)A1.*:9.;7C)FA:(HF7@%B:%F7/G+1!+$"(5E(1E<:;.5"=/'+A=69A)G35!6,=4<
@r3027
GTTTTCGGGCCGNCCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCNCCAAAGACGATGTTATGCATATGCATTTCNTCGGCCGAACAACGGTGAACGTAGAAGCCAAGCT
+
59-<#=<*''9.62C(23);3*+<(1-%B48/A?E(/-";"8(<2=72$C)B,D'/!-F(?$C<7"7%?=4H-*"6F*3917H?%GD(#>D2!:0$&G7)A&;%5707!7',?!3?-0@+5!#-BG:HB45?E8F'<@?GE)*&1A:3/H=3)917DB-!EB,+B&=0H5
@r3028
AGATTGCGGATATCAGACAGGTTGANACCAGCANGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGGGAACACCGTTGGCAAATCG
+
-;9)>&12ECAG='?&H+GEG6>66='H1";61<66>?!%4=4**!@=F@?F38F0"F%1(<,4H&9G6;>0@A.8-#/"'C/$,)&5E/!(+-HD1;0-);AH!>!4H87G&1.6?8,*756!$&>+/+B13C-/96,5$!
@r3029
TACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGANACTGTCATCAGCATTACGTCATCCTCCGTCATGNCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTNCGG
+
,5=1@&64.("DC/94)2589.=<5*12725!)(=3G/<%)E0"0E,3*:BC)1"CA0E,8EC!$3H:+18$06-:)F?=4)BCE6(>CC.<-0/"0:"<86HH@-1$E9E6/7(!$"C$,
@r3030
GGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGATAGATTTGAA
+
,,..F%,7%:6$1410B+3)*BC%EA5H@.18?659"9;%"9%HE<3G""6B@20<H"4D4402;>-#)
@r3031
GCCGGTCTCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCTGAGCTGCGTAATCTCCCGCATATTGCCAGCAT
+
5B/=*05@#!3<(*(?*#124C-&-.2C$"5$+*-G'!443+C@H/+7.3712A4(7$'867'&1)'1+7"E0"&";$92C8<D8+(6+A?8D2%F5>;F"A'(@F<>)=1/
@r3032
GCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACGTCGCCGTACT
+
=<.F97@'E1*G4&,.%?5%(-!3G?@G2>&;*@-%*D$F+(+<4F@G!
@r3033
CAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAGATCCCCAGTCGTCNTGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATANGTTC
+
'*6'-EG>A3A'F+.$+'>7<C!%2>%-'C%*")*5%.8=@4!8=*B5,%GB:'!@.-<B@.%0DC4#3AA?D6-*%<5=B9):%'"2=E)#$7$<BA("!.>=B6+9F307372?7;8(A=49%GG#5,9+5/*$"7
@r3034
TGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTT
+
<G9F(!76)5/<#(5ED0+6-$B"E9$)G-43>!:C2+G*A:A043"6)H
@r3035
TGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACGTTTTTAAAGGACGGTTNTCACATTCAA
+
7#&E=(6H5"=A,.6:D#"!%E<:!;?&.7D&-%&G3:C.9A=1()>E%E5"-G*+#.DD)&,D:6D)0E(''89$-?1001C;#-C($-+$.4.=@0"/549:*<B2.-"4$%.5$87$53FE0?:
@r3036
AAGGNNAATCNGNNNGNCAGATAACATATTNTTTATCTTTGCTCACCAGTTCGATGATTAACGG
+
&!"&"!'$"($&%!&""+!()*+!#("!$!(*(+!%%+'&((+$"+)"*)("(%#""!'#'"&%
@r3037
ACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGA
+
3/7=<(D4E83(8@2B099>>7E,:8G0'9*@0%(5!,A8085>H6'>.BD*'G4A+,:1F781.)!E3D(0%)9BC=)&?&0,:#17905A.HH*6F!C>/
@r3038
GGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCANA
+
+%%'+#%)%$*%$*)#&%!#)%!+!'%))(&+"%#(#&"#&(*"%!$**"$"&$"$((**&%!"''($!'&&%++'%$)(*'$(%*%
@r3039
AACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTT
+
H$=?+&$2DD5))449H#CG70C;1H@%)G)DF81213&+>0($B."'4"6932&B4(E*CH5,?9<+2@??-A;83E+&6G%90,$=+$>@3D'6&F=A2008)6@3."4B1D74;$",.8"304?&#??35E/C)'-5?).AD)&1+21)7%
@r3040
CTTGCAGACAAAATGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATG
+
FB76&>>5;-H(3+6;)5.@H(,>>G5F"(*$>6G%5-&>&>4*5#*7@@%8'<A'/,&C'2G*=4/3B=$'&!79G.-:A%E@/D:#2+>.0BB<=7,D;%.6;HA+!)B?3837@;;=#4DE('6?:'EA=8+0'>
@r3041
TCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCG
+
)DG?*B>D2@,2!+H.'H61F>)#660C)+"&/HH(!/@?F./19G,."C%+9/H75
@r3042
TCTTTCACACCGGAGACACCATCGATTCCAGTAAGGGTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCTCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTC
+
#,*51"=F1E9@:8-:'G+F#<5/F86";F<).)/!!4<#B5%0%/*B,2,?>6@9E5.<BA2C+)DC.-+6&8A=33:'%8%/;!740;5=$*8G$,3:2,5%6C2D40EB=3$64>4+)4,,2<E<*B/?B?B2:+/B-.('07@6D)/7
@r3043
CGGTGNNGCTNNTTGANTTNCNCTGNGNCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAANTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCTGACGCGAAGAAATCNGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAC
+
)&$#"&"$'*!!$)&"&$&!&")&#''+%%!!)+))+')")')+'&(!)+"!*&%#+*&"''+*#!)+)!+$)+'''*$%'+"%&"#$**%%#+(+")!&)"%*!'#(!+&#(+!&*!&+#*!#%($(+!(#)$(#(!()'$'"+*&*%!#*+#)#$))+%!!++#(+)*$*&)$"!%)#!%"%$$'#$+$)%#+))'")%!$(#%+
@r3044
TCAGTTCAAGACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCNAG
+
71$F864%3C#?>*CA!6!GCB'&30@EH=:1)&:,6#"@33@=3=#"?<5@3@'C
@r3045
NTNNGCNNTTTCATGTNGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAAT
+
"(!!"*)!*''&"')"&&&(*+!'!%&&)(')$*%#($(*"+!%!(#)*!+!*!
@r3046
AAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCG
+
=3-:BF6(1:F)B&!GE138@6?%&04!/8HG"&17$=:"D!1C+74/H#7D)6A/2#
@r3047
CATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACNCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAATGGAGAGCCATNCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTG
+
16C1)?BD,,$1:;6*B"!#$&3C!6>H9.9+0H&B0-;1+8<D@G;7#%#1F8)H#H@52C"F894118'0?1D+>0(:6$6=BG./<:)D*7%$/4F-H%7H(2*12-(*7$B'>%(#H%C/D$9$&*3#D.;A3-49(;#2!%C:!6#(,3">2E19!%='G1>H-A7F.!1#,D>3(<?'(C(&F7/(?($5)48.3B&'5:!*GC$+!8.+,/&A.G<:AF$776-@83>B'G>!;(!C,BF81B-&>:388#'/,C+918$!;G==>>6,!F%+5$7>2H?G%6H+1":+*B3,5#2D##G>(@A-)$AD729.<EC9C:3<=HE02H#":77='C(0<*+#6:B6G"A',.G1":8!1!6,*.%!1
@r3048
CAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTG
+
(%$%G$G0"!5=94H>&<-AH#@+2%11:@?#:+ED5*<$!%.<5=A21+G'=7)917-<1"->8#)5-2$,#G;#0DE&:-.2'E:38'0*#7D>8634<"*;H!3333%34$4/5!6FB$18(>3240*"0"9!6B>9=@F/DB.#);-;73B?)BEB&+
@r3049
TTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCNTTTCGCATAAAT
+
<0#A700(2&%A:?:/*1'7%/-AH2B14B>D28;59.9B./8.;>B?8&),A@7)E?5:&2E
@r3050
TTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAA
+
+!""$+%"%+"+"+)(#"!)%""%#%&$%)#%+&(++%+!)"&#(!'+)"
@r3051
CAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGNGATCTTCTGCCATCGACGAACGTCCCACATTGGTGNCTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCT
+
=C9CC#"CHE$-?(3H"<!:B>-7.59HB$B+6#E%';B#="406H0$9?,>G:D##BD01%CE1E+GEEG<$"C@*B>056#@)=8E<>3489:A)"=%2=8--G9,771C)%A>AA#%"3C3"*!5*?6H<<&(%66/*=")>&'40/:0#22801,?D&+:@2F5!9='-D,!831?-$-<A89.#90C%/7<B2'F8<1*=63A.*@9&;C,0!1+@GH&%<-9:D4@D4(+D"A7#F,2=,&DF?,+,;2DA>(*;G#:'6C0C"2H0
@r3052
TTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAANTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCG
+
4!7AFA@"7,8G"#<83+?*1)FC#B2G22=<#"(G)B+..)=1(BA/70-(81,E@!9)A4)3182*@2"77*?A&H*)+:!"*9'E1E<6#65*6D#B!#,C>.G(3#,24==."%3C-7,=G$)!,C,77'HED4H?1E0.(C3F@->.1#1+=4;$#2,-<>D=<!5:.89H!(B'/%61>H-$)&/A+?5E3*;B!F&D(<'C,';/;=>(9#!!>4?G)'!6!A./8"$0'/;+2G51B/E1/A=+BBF+
@r3053
GATNAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGA
+
)%$*&'*+%(#"%*&()"+'"(+*(+%%"'&+"+$#%*!!'!
@r3054
CTTACTGGTTATGCAGGTCGTAGTGGGNGGCACACAAAGCTTTGCACTNGATTGCGAGG
+
&+)''##+#'+"'$+'!*)#(&!+'"**"#$+&+#)!$&*#$+%*%''(!$++$%'$**
@r3055
GCNGNGNNNNAGNGCATNNGNCNCTGTCNNNNNNTNGTNNNNNNCNNCNNNNTANNGNGNNGACTATNNNNNCTACNCNCNNCCNCNANNNNNCTGNG
+
"!"#$$##!!"####!#""#$#!##$"#!"!"!!!!$$""!#"#""!$##!#""""$$"!"!$##!"##$"!$!!$"$!"!##""!#$"#!!"$!!!#
@r3056
CCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATNCCTGCGTCAT
+
B.;5',D+E.5',87G137%D.5(*(:04<(C:2(;(*#+1+B>C
@r3057
ANGNTCANNACCCCNNTGNNGTTCAGCGCGTAGGCTTCGATAT
+
%*"#&)'#"%'%$)!'!(&'+$#)+$*&#(#"(%#'"#$#(#"
@r3058
TCTACCATCTTCTACTCCGGCTTTTNTAGCAGCGAAGCNTTTGATAAGCG
+
2H;4@)12H2,#6H7#F4$B#062B/%"-@>!FHF)1.:DD0E:H%!<0-
@r3059
CANNTTCCACCTGCTGNTCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGC
+
**##+#(%)&++!+(")"'&+#%)$(&%'!'%%#'(#!&+!$#$")%"%*+$*'##$$""*&##)+&'''&!
@r3060
GANNNCNTNNGCNACNNGCAGCAGCGTCTGTTCATCGTCGNGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTTGCCTCCCACGTCTCACCGAGCGTGGTGTTTAC
+
*$##!%("&"*$'#(!&&%+")(%&(%(!*%)'+++"*'*")#*"%*%*!'&&$*!&+$!+!(**#($$#)'%)**&()!*$#'"!*(&$%$#"'&%'#'#$)"!""%"*+#(+$!)"#&()+'"'!"!$")!(&)*'$'!&"#&&*(!#%!$&##$!&$'"%#(%"#+&("#!(!+*"+'(#)"'&&)'"$$!)&!"#)$()%'+!$$("#)(''%+()&**$!%%'&*(&&'"**(*%)+#!%+&%(!+(#+**"*())##!(')
@r3061
GCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGAATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTGCCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGA
+
CH)8A2/,040A0F""*16E://"9B4D*5".&;40"#$#2,E*9D..0-#;3$4):@&$A"9+2/.></=+7E#';307)&AC-9;*H8F.!!)<B%<0$B<4=F4"3D6:4*7G",#GBB;3-))F?7GA&#<+-D='6*H7'9C"F1"$:A2":35>=7;15D,1@(H31,:?B
@r3062
ATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCG
+
*9A(?H86$+26)<#2;22DC6E<%>"%<57-057")&G.45$<,27,=,,6&7,&9))F>?-=>>0)G:7@?>#=6@!+
@r3063
CAAGGTATCGGGGAAATACCGTGGTGTGGNAAAGCTTGAAGGAAATA
+
;=E72)&@&!HE!<%;16.D)9.<>2<&.8)B-HCC,&FA&!3#>+"
@r3064
TAATATATCGNCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATACATATGCATAACATCGT
+
E4-@FEH6*&AB7*)/DB(H.0H8E(7,'*H"87B92G&%'GD#.5<4:':1#:C>@-2F;F1!=BC877-C-%'8&9,1
@r3065
GCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGNGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCNCACGGAGGCAATTTCTCATGCTGAAAACGNGGTGTACCGGCT
+
8$*#A;"G$F#$-*+6E'#>%*14@%4."-&*DE0=9CA/"06=<8>/=:D4$97-5G=1H,;;!&@?&:EE840,B=6*!<5#*4%8"8&?3,@;5#*$4E#33:36+&6H?0"6).5B"9>H;)6)BC)@.+$D"7E;=H#:9D@C#AH39"442F;#G&=":>=@-,@*:9=#'3>4>:21:+7>D!&-3G0=
@r3066
GATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGNACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGA
+
E:F6:,*8(DB!E1:*4-%49:5>A36'C#+1<:-/0,4(&-<(8&DC@E7F(=9;>4F5+?*("DH*/D7##5.!:86+092EC&,->B'F:!0F;&1B=F?(.&7;.6
@r3067
AACGTGNTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAATANTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATC
+
)+*&&*"!#)&$%'%'#+***%"+$'""%"+))''#"!(%&$*&*")"#('*!!$%!"#")"(+#'&"!)&%'&"*%*)#'+#'&&++%"%*"()'$*(')%'+**+))!#*$%&**("!+"#$+#*)*&*#)#(*!%&))"+")%')'$#&!$!&*()$+#"&%+#+)#'*+##"!$%$*""'
@r3068
GATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCG
+
@DCG"F!FE+1&,'%E?6??AC*;E%$:=*.&G9,"#>*A9&!(2#DA?(#7&9F76))14@)&DH3><+$;60:39E<@@-(C;6('&?D2&,3#E34H7#8..0$6*5;<$$"+B-#01>EE9,AD9#&C+
@r3069
GCACTGCATGACCTGATGACAGGGTAAGCGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGA
+
)H18DFD12A;<%:(!A/"$"2,<%/#-(H5?=&B%0/->)-EF-&,0!C8788E.G;?><5D:HA:(>;8''82<$(*(&@9*!E@0>DF0*(EC4!=A?0C#17#H==$GB6(B-;D92B68A
@r3070
GCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTT
+
(3@=*5A3D)$#<-H$H:59C*+46,C0E-'"G7%;D,-.8.:@D3*#@;?.''1?"2+!4H!%+$B/"+C:6
@r3071
GATTAAGGCAGAGGCTGCGTATAAGNAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGANGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGC
+
7.?=(:CA&::)+<E2H(7/!+E&<<)DF?.!%(1=?F4F4F,#C+";6+F#*$;$8/4;34.!5@#?/H;3$;&?-!$E&#5$4)E)$5'?(?'@D5,5#AC7C(4A.:*&F.:-+.*0G@&
@r3072
TTCAGGAGTGGAACGCNCGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTGCGGTTAAGGATGGAAGAGAGTATCTGTT
+
?G$'-),'-@("G$E1.5'',E=(+1#C"D7%33)*)-7(,483>&C3=CBGG(&83D)B"G)<G#+E$@>9+9.F.0&.1+,+"A"B92/2"E8=&;5CC'E.(&<,*=2)G%9
@r3073
CCTNGACGGCTTTGAAGGAACGGAACAGCACCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGG
+
*:**8,2(8FH?9B9CC:92+37D>/&8<FBE?9%45>D-!)FA<G9-'!&.?5:1=;FHE=@?7>'>6=!A7)@
@r3074
TGGAAGCACAAACACGNCGCCGCGAACGNCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCANATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACT
+
30'@E:1H->2.DA0GF!E&A=HA2FE*/.=:&5A0A/DHB5):D=&15CBE?#<$-C6-?)/(#:2G'07)D8-#D,$E;<8A;"(>24*=?5/B:=B39G8D+C>,B%8-;'9<AC@E9-*86/8&#*&?=!)7(?0+-C?D3(-*976<!>
@r3075
CTCTGCTTATNGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTNGACTGTAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATA
+
+*%&%*+*"'()$"(*$#&#))&!*&!+$*%))*(&(!%($##()!*%#)"!#"'!)*%*!"+"#()"&##'**++*"#)+*'!!(**&!$*!'!$!((!(##'*'&)'!%!"$+*&*$(((*!"#)&()(!"'%
@r3076
GGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGAT
+
'EE*-D-E38,*,!C:/&AEED/EB3<$$-2'??A:$&%A%>:31;"5B-4C=@#!@:9H*,6##<3?&%1#1%+47G1&#%=
@r3077
ANGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTNTTTGGCCTCTGTCGTTT
+
3$GFB*56%8#HGG!-2.!7H<,(>D/-0C"1D/E%G76->H*27EE2=-*9:%HD;"96B,0$*!!(6-'+;C"6$4CC?FA8//$/5$2C++BG9<G&%:7/&=4.'%
@r3078
ACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCNAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCNGGTTGCCGACGGNTGGTGATGCCGAGAACTTTATGAAAACCCACGTTG
+
)')+!'!%#*+&)!*!)!#!!%$!(%("&+!&#)$!'*+*)%((*)($&'('*#*''%&!$"!%%#&*+$*&(!$)'#%#%%!)*+!&%&!(&$%*'#"+"(*$)"(+&&!(%*(((%$(+'*+%!&('*'+*(*$%%!&'#*&"#$)()*$*%!)*"#
@r3079
TGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAAATGTTCATAGTGTTTACATCACCGCCAATTGCTTTTATGACTGANCGCATGAAATATGGT
+
66"-$A1'!A8G$@<!8"/')6D9A"/$F+"*81/?:?@@/6?<D7,@493/@DC:$H'33G('CB2%=<7)7((%4++F3@/B<C8($C7$E1HA-,98''A(-7
@r3080
TGTCACCGGCATTGTAGGATTTGGTAAAGCCGGCCAGGCCTAGCGTCCTCACATTTCATAGGTAATGACATAAGTC
+
'!.5&"@HEG%$6&!2F727&85D#&'+-$3E;18;#4A"4;#7H,/73=3!:D/%B#.@@*G$!;54/#>*-A%%
@r3081
GCACNANTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCAATCCAGTGCACCTCAACGGNATTATC
+
!%!"&#+!&+(#"(*%))*%%!+$!'+(&+#$(($*'!$)&'#*(&+'#'(*")&%$$&"!!+(%)!!!%$$$)+*
@r3082
NAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGCTGTTAAAACAGAAACCCAGCAAACATTAGTAANT
+
*&+%#&+'*&+*!$$&%'*'*#%')%%()+$#**'&%+(%+%'%#*++%(&*''!")&*#!&")%$"'+)$(*'+$%()*%('(
@r3083
GCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCAGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTNAACTGAATGGC
+
@E'1BD,(9C!9B333%A).9;9';G>5#)1AC0G07FAG/268+G=H$9/A"?#*/9B'>3.?D46?2H7!7'-C:&)326-62#8B5H0/D5H24<."('3&3,%@A-E/.*HG,!%BE$"F;1#5AF<F.59??"7"@'"BG><9F%A*.#$-05>)9*,
@r3084
ATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATG
+
7D/3:.B<2B#$8/#H8D$2-/+*$1B5A#F3E+&(FF"+C1BAF554#F/22B63C;D
@r3085
GAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCAT
+
6A%7)G><E?'B%#,5H.3>GE&D$D<'E2D#%,:(633!5)BA/>
@r3086
TATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAG
+
/#!G'D,&9!!8>2/:CCH&=F<A5H),=A#7(/8B@>0;>/!/.F'+9+*7=F(/(<06CC?!.E**?69E-F-
@r3087
CAGCGGAGAACATCAACGACTGCTANGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAAC
+
*+"'&!&*%$##)$*"%*%)"*))++*'')%%""*$%&%%(+'%(&%%'$+"%&!!(*%"*!)++'+%)"+)+*%*$#!#'#&+!$"((&
@r3088
CGATNTACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCG
+
*)*!!+*&#('"+!+*$'%)('#!&(%%***"#$!+)'*+'#$#"&(%")("+'!'*&(**'##+")*'&
@r3089
CGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACAC
+
*$/!:!@<E*$@%(;:35"'('>F.-E.?<,;<4F%*G5>-2!E#24D5?03<BA'(+563%B
@r3090
TCTTTTTNACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATATTTTTCTACTGNAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTNCCATCTAAAAATTAGTAGTATTG
+
.G9@,$9D3&E@(&<5D752><1B-1,'C/.)67?==&F/7E6(G9?-*B0,40%.!>68#5*C/C:*!E,%BD*+@42E?;G//B1E"A-C=;@%8@H1F>A9@>86'1;&/'598>&3>:*>/'<'13>AEA,&B6-22#4H46(3:!201A"H'5:81)4+F$5:;(%3/FH%=-3?B(?.-CE;2,+/C1-9)%&>A'H03:9>;3*5$';2C#@&F3CD58)+F.+G"$,3:+.<E@H(>=.!')7$C60%5FC96*.2;6-G403#$4)D:#GA;(HF@!FCC&)<0&D2G9<-#)(
@r3091
TATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGG
+
30*G01DH427+97&H,A0E84";.6,F;7A<$>7??6G9;/&58&
@r3092
TCNGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGNATGTGGGTGACGCGAAAAAATGCCTGGTACTT
+
;FB=.,G%G.B<?G<4B#?9DB",<2G6,H'A>2'.-B>086@AGDE:%%<9)/DD33E1H+4%-<;AC':0;?H,-5,H"!8!$
@r3093
TGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACCGAATATCACGAATAGTCGGCTCAACGTGGG
+
(0CEE01A,0,-7DA1+;1#18$B55!.BF)*D)2;F#23;+!;::0#3;;2&$!&>F&@("A;!=;*;!9(F,(19AF;+>9&2-3@&#C)!&3150@;C<
@r3094
TCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCG
+
H8,F$AC#F-#F@4@";7GBD34&$4/C./<#4A8#HB*#8>8$7)4'D""(4*"9%C'2/HC/1B
@r3095
TGAAAGANATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCAT
+
//GF:.&#45?*C/@*!<&%?>#.A30=;""!E(-4=5'6!=?6&/=/81;,>D:.!/"<44*+98&)7:%!D>H5=7=*:B'E*$2.(<08@">7>9)044GA<72&1@;*5%2687.67$69<6"FA<;@3&F+8-!,2G28=FC@-@=C)E<'@;'%(C8B7D"42():2,E>=)F!-+9+%%C1=;65<$%3C/=&32>#+/)*(#H*GE++!8D?F/9CC"9BG(;HG#".
@r3096
ACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCA
+
CB1<D;"4FB;-*E(,'6"(*.:$(EE<?6&=>$H53=#6D:$1?CB6<E2B'+,(6F7H#7#)2A"4?!FGF)9/GG'9*0$<5EE)0*@%1))D717+AF7F7%8?7*-5:0>B!$$>?#F%5+C+B=,(0)*!C6H'6==39$!<F
@r3097
ANGCAGATGAACTTCCGTTAATNATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCGACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTG
+
'8+/<'%9C#&+=E5E9FFF&=*-"=78=9;41*$7=-=4E54?3!AA&B:?-D4F+.D8D(GFH!(G(:E4B2A<H&"F@0$://46E>9>."+B.(EH-"@7-$GG%6)D&*A$29#'"AF7E*'
@r3098
TACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGA
+
A4G48'=8.2*AB+-<D!>EH@=@AA-:EDF'60/**B;2G"=A$&$4''24EG>:00,E3D2,
@r3099
NTGGTCATNNNTCAGCAGTGAAACCACTCAAGTTTGNNAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTNATTCAGGTACAGGGAGAA
+
(')*'*$%##%!+))#&*&&&&(%(#!(!%')*)'!"'*!'(&"($'*(&)("&$'#!+%#$)"#$!!#(%'"!%$(#%&'#**!((!*&+#*"%!'%(#'!#"
@r3100
TNTTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGG
+
%"9(9E4+&//;/&7-)6$$!;H$&A+$)=!%2=<<25:.>A,!G!B/%<%C%%4&C%!HH,F+@C'B33
@r3101
CAGTNCNANAACNNNGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGANCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTG
+
((('#'#("&#'"%%&(%+$#)"(&'!((!*"')(#+'*+&+)#+*$"("&%"*&"&*"!$!!"))%!#*%)(&)()#&!'*&'$%!*!%()#+(#!('*+''$+%"%&!%%%!%+('###%"##$&++)'+((&'%'!
@r3102
ATTTTGCTCATGAACTTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGNTCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCNTGTATAGCTTCAGTGANTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTANCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTCCTGATCCTCT
+
F9>058+8G?;$#*;4$450/<7=+9>C99G,@C@E0#0"&=3#EG'F%%,5"1:6=9E:5-+4!,>=66"G21?5%(F!@=;..#-*5:$05&).48.C"3354>.",F'46&)!%.)2>7<>&?&4#)#EC&'';GGDC?(.$1C+H<"-G?*.<,?,E5)&)9%$0A$?9D7G6"977E&=A8!?7&562F-1G?6</25,55?,63!/G#/<G"AE8A6/=7"0(1/="&,*H/2#C74BD5*?39&<+7?86B>/E)C4.E6%&46>,!*;@3,;8!=+%F7EH7'8D&)79*6A2FC<ABD+<<C?*.18H3D8;(F
@r3103
ACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGANACGG
+
@.@;GC&$$F:')D9;!-E!>B76*2+)2.F55HD9!!+04F
@r3104
GGACAANGTNCNTNCGTAAACTNACANTGTCTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCNAGCTGCCAGCGG
+
()'#%"%*(!(&$!*$"&)&**#'&*!$)*!+&'%)))'$%+(#$&"!##&$)*"#%+&&$%+%&#&"(#''))*#"'+''"''%%($)"%+'&'")('##*%
@r3105
CCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAA
+
1)H24)/52(@&#/H*=--!#$D5($#)5B":,&<.GB7(C"G
@r3106
CGTGGTGAGGCGATCCCNGAACCAGTAAAACAACTTCCTGTCATGGGNGGTAGACCTCTAACTCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAG
+
@BF;C48H5.!.51/.&D'=8@%%#-2?=#:&8%'@>)(E0=8E4F"H$<F;+<5*E;5B0+A"<=E9D.7-@A:'77#FFA89=5)0"B;-B4./$;289879(=::49=&A#(9+7C!$'>$B
@r3107
NNANGTCGAAAAATGGGTGGATGNCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGC
+
'")!+*$!"+%%*$)#+%#!%"$$!""%(*%$""($#*'$!(#*+%+&("$!#$!'%!&$*$+$+!&(*#"'#(')##&&'$*""***"%
@r3108
NNGCGAAGGTNCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGT
+
$!%%!'$'%"$$+(+*$('"+'$('$#%!)%)"!%(#$(*#$#&)#!%+"#(!
@r3109
CAACCNGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTT
+
;9*,,C4)206A"F%F<76=4&0A)EE.2(1"C>*$%'&&G>'#%8<*F!F)4GDE59'08(1(G
@r3110
TGTTTCTCTGCGCGACNTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTG
+
;@1-$BB0#;396"'<?393B;CE&!B/8$G3%!,F8808$6-1#(%;68=E8%DE&;"!9.<74A4?:A!)!",8*44,C7/*606>G+79EB!(&F"3!=4!0:);6/F//'D:
@r3111
GAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTA
+
G.=1#,4?8?-?.5#,33>+'$/),0CFD/B'B.13/93>+G4)(,:62.D4D"E,,1.$.2G=%,(F)35H-?ED2H9E:E<(';7*/+&11;..2A8'/3H=0-D/%-(4@0.-.-G=E=4(3.ACE>56&68.;
@r3112
NTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCA
+
)EC7-67'<E=05D@/A$H$/1>52A;70@.(&<<!"5<:B@8
@r3113
GTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTG
+
@/8F1+<G:##/:#5=3<A'CF)+4E$6$)93E=/;;5EE;
@r3114
GCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGA
+
H('<6'#0G6>CADG&"2E:;.F%<>9ED38*9:4.-7#5HF4*'F('%H=G<BC*D"?9&0.69A2,FB++@CD)4E'&?")5E45$C)!-.5$D"B#<''H<,C.F.;
@r3115
GACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTNTGCTCAAACGTCCC
+
))+!#+**&%+)""''#&+#%+(&!")'+$!!&)!%+&#*)!#*!%#'%&&$%$)"!#'++(%*
@r3116
NCAGTTCATCGCATTACTGATCGTTTCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACNCCTTTCCTGATAAGCA
+
#+!!(!(*#%"*($"%#++*#'#*(*&!("+#+&'#+"!&*'*($!++)&)'&*#'"+"!!"*+!)*'""#%+*"&!#*"*%"+
@r3117
ACCGCCANGGGAACGGATAACCTCACCGGAAACAATCGGCGAATCGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCT
+
";7C7""#@2E;;"D;,&&+*:)78/@E-A$34F+>5%.-!98&3B.>/5);,3;9/A?D2E/=DEAGAE4D/H#"'24<(.))==$B7.2G7;:ABD)*;EE!A.<9D.55"163)>(#$(F8D.5C(1'G?=#3;9*45E'$9-6#;C5<"=/&B8+G5
@r3118
GGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGACTG
+
)+#"+$&)&%%$"+*$'&$((!!'"!'$%%'#(#)%!%$#'!"*'(*&'%"(*+&+(!(%&"'++(#&+'#'$'#*%"(
@r3119
GTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCA
+
CE-#8E(2+!="28@*)73?0)#&!A%G<20>EC-*B@E)>?F5/E(%<?1
@r3120
TCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATNAACAGTGCACCA
+
'*/=!5G+@E6(*9>+G0/76!""(=G40,=%9"$2,74@4+HBA$)A>#9:&E55>A%$('A2<,*%3C<6$#B+%+7FA8'+3-8)6%E5914=;B>0$8@5EBG><,EH%<5;2H$'#9!1.B40A*00,=8GE:CF$#)$#*G;?C<D-88./)@<<56D5(E#G7(3CA*1,3*=":C.,$32:F22:%71<%#F2B@<('!35@11A@(1D3C2"8!>)88$>B+)F5E-"'E1!/.9!>:'05+C00&/B
@r3121
NTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCT
+
$27E.F9HH237.'8='8D2H@%+%/H27F(G0#>2?,>C0;22"5/6!9+"B$/1"7/.671A&:?-.9::85G3*!5)6<>?91>:.C"4&7,?'9.BG!C(C84+(FE;DC7-@:<
@r3122
GTACGCTGNCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTNGNGGGGTCATC
+
1?:8>$.(?1@$9(5(H"12/+,407:%<6/*!+3"),5%>1!+/54-;%DB7'%E'D4C>0+9EEE(D35'#*%1%=&E/>!(-,&"'=5C>E:"-G7>#9:G212!/FE.020?,3>0*$+45>3"7650;:),<9&79FF)1&!D5HFF,&#7G5@7;8=':37CA&C<A%B%B-$@61E,0+4?@)@9'1AE0B
@r3123
GCATCGGGAATAACACCATTAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACANGATGTGCTNAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCNAAGGANACCATCACCCATCANTTCTTCGTTTCTGGAA
+
1-?*>E@H9,A<+D/<&;?B'(4'2.0=<F-4/F@@H8G=/#B!<GE=+.$8)G(G?;AF18;%5()!-'4=(!F1EBG4G+>!63+&%#D7<?39.'6=&A0C3(F8D.+@1!#%A@F3C/*A3G'EF1B%&E*E<+&;.4&'?D,;?GC73
@r3124
ATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATANGCAGAGTCTGGTC
+
/,BB#)EA=G/)F@2D"1&=<2@GAC/E>@2%.HG11EHC$*'*/$!361')#:4.%!B:5.(/,4!$2&%0(,-CB&39?",.,;"/.)<$?EG@);7<0D-$'<-G8'>G%-&G*
@r3125
CATATCGGTTNGTCAGGGAAGTTGTGAAGTTCTGGNATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGNATGCCTGTTCTGAAGCCATTTATCGAT
+
;";!8G.&!-6C>C2+=;B./B33&E609#!(=+>09!$,'-7=E>=73$.+A3+7#-?;-).-''><2#5D')8>DH04H-3;)D('B<.9+(1$@C$$/(*3,4:0&=)@GHH+/@9:B>>',A8H'"5'B&=#8E#@0)$,(@*"@D;9?8?/*)
@r3126
TCNGCCTGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGANTCAATATCAACCTGGTGGTGAGCAAT
+
D"5@!C5?(8H2)?8-@?3+@=?=A:D<%.3D0C%"B3A6045=#,>E59$#,8,&HH*<:>&F+1)B$2@,#E,F+B>*74"?C
@r3127
ACCANTNTNGTTCTGAAAGCGGATTCGCGTAAGGGCCACCGCTCCCCTTATAAACCCACAGGGTGGTGCCGGCACCTTTCACCGGCATTGTAGGATTTGGTAAAGCCGGCCAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGNCAGATCGGCTGAACTCCNCAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCT
+
(()#$$$%)!$*+'%)%#')$!($&$$&)$$#(%#)'(!!')$++"*(*&#*'!!!+$!"%($&$%%!)%%!#"##(%*'&*(!+'##))"#&$("$!+))((*#''&*#'((&)#$'&#*%"*#)!""+#(')($**#!")*"&+#(('%!$'*+"('%+%"("%&&*)**)$&$'))"*$'!%)###%'$!"!+&*"()*$"$"!+)"'$()&%$$!*#))#'$%("'%&+!#+'"("#"*&"**$'+!($
@r3128
AGCCTNCCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGG
+
)&)(*&#%+%)(*&++)'*+'##"&+%*'(#$%$)#'+)"(#%"!%%$*(+
@r3129
ATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATC
+
.EH$7H+>!D<>D'C+#E66*/"&5;<"-;#)H6#DH<.&H'812,4@-'B,B"<$(*;%!%'.&,"H&%*F,""473'+5"*.7BE?6BFDD#+>*7A-=#)(2B=!6F52@#C6.5.3C!E"0GH$6*'H%<9F86>5#2.C&)/9B6D(#17>D"7*2):.D#C+,(0?7$-'"6745*-5(#
@r3130
AAGTGAACGAAATCCGTCGCCAGTNGGTTCTGGCTTTTCGGGAAAGCGGGATCACC
+
ECA2*2@5DE,"<H*=$*1A:@'<;D5#.!8,.EABC#.$6?@&80)-$6',7F.(
@r3131
NTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGT
+
.C=@A9/4>76=9>9"7908/(G17)988E<4C7,%&&"#6HF)DE-C-D3469$,11/6=*)+*C"<F4$&?'5,!88E$'E2"0HHD;!/.,7<;,FE@C</3+&F)7$H'?2:98H#,?+E$8.G5F=+:=%DA#;(F8&B4+F')834*!
@r3132
NGTTGTTCCTAACCTTGCCGGGAANGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGG
+
)%D-E/"'<&:?!3:?;B>+4#%8!0C6CD*F'@129B14F(93A&G3E-%6C!8;7?
@r3133
CCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGGCGCCGCGCCCGTTTAATATCCGGATGCGAAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGG
+
3CH+"#5CF7*6D:%B#F!4GA#>H1'G#2@F*>B8'*%$4F53.6>>865B#D%"">(<<->:&"D2B@A0-2%E:>&534*<02"2>46DD3=GD=C6C2D0,'$.)<-3+@E,;?);-?*GH10'0G4'*:&&08GF%DB;,$##F?2<2!5*DC?:17">?;F-<0(&2.D7E):.G?F:%$0&C<F=)9+?:>8D8E;7A+-&?(:9BC$+AC2&++.0AFE6G/#9;+3H-"9&#"3##.4:9H/D'
@r3134
ATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCT
+
(*F&@,486@F1(+)2*4,E,F&/B%!1BC:(#A9%93.@<A0A2($2(#=E
@r3135
AGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAAT
+
*A&A+;2;-!<!=9=)C97F:AB91?"E0;4.8/?A5*?&F&"!G'&4&)-BC)7-$<G/*+EC(3
@r3136
TGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAG
+
4(!,90$;4/./:36*:7</C1%#:0//76DGHGC=,B!%</
@r3137
CACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCNGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACAC
+
@9,'6-1GA@"D,'/0/D@-4C5>C97F3&H2'E9@9F$67A+.&!53-!@/B%B<A-/765#C#F:*C,A!?>-3)(;%'5<,;=
@r3138
GATGCGATCACCGTCAGGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCNAATGACCAAAGAGACTCAATCAA
+
96A89A><4A,E6;+,CB56=4&)/5"A,#8F==!D#/9'+@:2$70:/853C?A>@:+$1GB6CED)=.!;8/,9$)"G'E-
@r3139
CTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATC
+
09H8D(?C)@:BF,0('8/*).F3EH1&//;7H.',(<*+:.(63'=9:E-BG56>?;&C.4(CA2G3=40
@r3140
TGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGATGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAAC
+
F;%.#@1888-:)#3<"."/HGB,0&'"G$*!>4)1F8'4,A>C5$!.G&))(<G/*4GH3AB9,'D14(-&9+254+'@!*''D#520*F+*?.B*0G31%&!)*G1@,'2?83A:/$58
@r3141
TCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTT
+
*,F1-&7HH<:8%B9-4736!,C)=&F,+%CEA+8E?/%>)#)?:;'//H'EC?B2<@*D.!-"4:H-?6"4+/();7G93G8/B5".
@r3142
CGNATNAGCNGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATC
+
)(#))"*!''+%)&&&!&"+#)'!!!$*""#((%#+*"%+!#()%'&")*""+!&&$!'""$%+('#)(&&+(+'!+)+)#(%!'+#'$+++#"")+$%(#$++")!!'($*!*()%''*&
@r3143
GCCAGTCTTCCGGCGACATACGNAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACNANGAAGCCGCACGACTCTGCTGGCGCACATCGCTGGGCGTGCGCCAGAATCGCTGATTCTGTCTGT
+
D0,9A=8FBH%<-9;.0*4=&8.7G+1,,G)H.)&!*H<=+!;;78?,+H-76&@C'>.3GA*+@HB4B=C<"-%.G(58.38842@>3<0>9C,3G(*A/3@H((CH*1),*<,"AD'F8C?!(.#B,2%.+210>'&+1/"0%*DA$-+GG;<>,
@r3144
NTGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCNGTCAGAT
+
'#6)$//5'H5&H(D=#""('B//1,-H,4@+.+52/CD'2>9$ED0F.F2H:7E=+HG*F5?7@#'"C1+:0EA,F($4#
@r3145
CCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCA
+
4C(3&+1321-4%+B%3<6"@4H-9"7;0B4(!=F&,:*0=F@!$%+F>DB='7D>6H$F-!>$D,F/7B/:-3<"505
@r3146
CGTGAACGCGTAGATCACCGCAGCGGTTACGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTNACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATNCAGGGGGCACCGGCACCNCNGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAA
+
0>?8<@'226+3&D440*#A!B$?0(@)2)77F%E<1*9/D222BB2;'78/B(94+,-GB'C?/?<8@C0+%,C8-::!A)4,:0/G-&<3F@04<!)0$#!#:4;9G+'"@@B+*8<6652F'G!73-6!'$1/;9<$D=#;7<G#*1</EA9>B*$)="9-1%E';;)>6@.0ED&2-A:!)#8>@8*6*2A"A".=/+)/9D-6<%0'4A#/#6#&8/H/6('H'/#8,=B53%FA7""<*A8!79BF*:-D@'-';E#7"5'B6)2!&?1>CA="A?&
@r3147
TAATACAGCATTTAATACAGAGCCGTGTTTGTTGAGTCGGTATTCAGAG
+
@#8//*?EB=-<8#B5C&>5+/2B$-!$4A,7%10H!39D-3/1'<7F$
@r3148
NCAANNTNNNNNNNNNANNANNNTTTTNAAANTGTNANTAANAANNNGNANNNACCTCNTCNTTNNNANTATNTAGNNGNCNGA
+
##$"$!$"$"$!#!!$!""#!!##!""$"$$$$"#"$$"!##"!#!$$$!!!$!#$$!!"##$"""!!$#$#$$$!""!!!$$#
@r3149
GGGCGAGAACGGCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAANAGCCGCATT
+
/<6/+0#8"F!D=6EB)"HA+(F+3'250D&3H;,H017!D5;!GB:(!A!GB#E/C4F-<00-,$4'H62&!;@A=B=
@r3150
NCCCNCANTCGAAATCAAGTTGCCCTCCAAGTCTTTCGCATGACTCAGAACTAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGANACCGTCCNGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGGTTCCCGATGTCCGTCACG
+
)*)($%$&+*$"(*+$#)*%&!%$*+*$$)!')$"%!"#+&"&!*$!&$"!!''*+)''(#$$!(+)*&"'(#!%#)($+#"#*")$&%*'+&)'$*)#+)#"(#&#&&+!*$!#+'&"'!%*!$!!(+'$('%#&('*#+()&)#)%)+&'''#(%#%'%'&'*%'$#%'"!()#$#"&)''!"(++!)""!!"!
@r3151
CNCCCNGGAGTCAGTATGGAANAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTNTTTA
+
)##%*"+&$(%!(###+('$!#(&*'!!!!%$&%"!')$"")$''"*%#!*#)&'))*%""*)'('%+("%*()*$!+)%*!$$+#
@r3152
NTNAAANNTGNGTNCAAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAA
+
'*"))('#"$""#"'")*+&*(('$#$&"!&)$*'+%((*+!%(%*#*"&%$)(
@r3153
ACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATG
+
F$;?::+>5=:'<:#8-F8D)DB0BD06(>+/67>45!4F&(%!8B2441C'@=%H=$-&
@r3154
AGCGGCTCATTAAAGGCCATGCTGGCAATATGNGGGAGATTACGCAGCTCTGCTGTCACTCTTCACCTCCTNTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAG
+
$5@.6AD+G'/1G<@,"E.)F@#?G3#%0&=(($,32(E!&&97&*07=<+7A#:(?7631G<@7=//5"1>D)>&,!)9*<3B5G+#HG87FF/<;6F%+/4/:'64"&;@=.(4H%?&,5<)EH8?3%7>&@(%!;-=!75*'@DC$&>!C!E?$!@F6;9<-&)G=A&C62G%A!"='2
@r3155
ANATTACGCTCCTGTCCGGCAAAGTTACCTCTNCCGAAGTTGAGTATTTTTGCNGTATTTGTCATAATGACTCCTGTTGATAGATCC
+
5$@&2+%H9?=B7;GF5#"G8*$&8<2<E<;8+#5HFBDF+%6DF,0!!0B!:C:?#8@F)6*2+$+)8<&H>6;82.#,/;C9E:%
@r3156
GGGAAAGAANACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCT
+
'#*(*"+*+!(+#)*##*$*&%"!"%)$%)&''"""(""!##(*#%&)+%('+'#"#*'*)"*##(&&")"#"+(+#)
@r3157
CCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGNGAATCTTTACCGGCTGATGCGNGGCTATNC
+
0F-8"-E#.%/F"6"4!!&B)1.%?@$?5-3)7G!D0-2DEE8)4)"09C5"@!7.&H<G;=-G4EA((C$A,6D;%'G?#
@r3158
NAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTT
+
.<1!;.C+53A#,7+!?:*5/B.F.C1B9,A*/1/6(+="*$'20
@r3159
CGTCAGTGTGAAGCGGTTATAAATCTGCNGCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTANACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCG
+
&9AD9:;='2C+!)="D6)HB45(B#.8BC(C%5F1,66;3EFFC8B8/!00=/A!25D)&:93-,>"'//3B6!E36$="A#CF)1525A(%<H/+9GEC>8";
@r3160
TACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGA
+
C?"52=)5=#+F:(@!$>$(6%'/H8!$6!#+5C.?/+HFA26/5+:C,F?B!5B'32(H838
@r3161
GGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCATAATATGTATCA
+
&(4G-<9G,,:"A&8$9HH6+#$7!&7A=-F/5-*E77G3=!6<,*:($/
@r3162
AACTTTTTTATACCAATNTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAANATGAAATAAGCGTAGCCTTTGC
+
.E<).,-'<H3"0(!5C"3D:H2EG.&">@58/DA:%-C3%B:>7&4-8''<:%#9=F<8)<:,AC)(?6:)!.1)-B4!:E9B(+B>B%"4
@r3163
CGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATC
+
))&"++%%)($!)!%))+*'!&*%!)#%)"(#&%*')"*$+*&&$'*&)%$!*%*"&**'(&'%!#!((+*)'!%'
@r3164
TCNCCATGTTGGCTCAGACTTGCAATGNAACTGGCTGTTGTNACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGATCTNATATCNTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCAAAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTTCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGAT
+
*%)+%"**+%('%$$$*"!)(&$&$&'+"&'')&'*")(*+!$%#!)!)!"()!!%(+$$#+!+&(!&!&#&(+#$)*$*%')!#&)!)"(+!*$!*'")%!)++"&)(+"(%$+#)$*++%$(!'*+))+&'$+)($**""%$+*%#$+&*("#'''#'")'#*#$(+'*(+&$#!(#%)"'%%)%%&&%#$$))&"('(#+!!"%#"++%'+'#$&*$"%+%)'"#'&#&(*#()##*#+)&'&+#+#!+*$+*#%#$')"'$+*""%"*%%*&!$*+#(+#"$++'*%)(#$##*%!'#&*'$)#$!!!)$#"&%&")#$*++++#!*"*"$$+'""""')&*%)**$)"!#'&'%!'$'&!'$"%&'!''&")#$'+*)!$&+'!)
@r3165
GTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACNTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATC
+
A8&0/6/#*?@1A4$+(/$"G#8F0B@64>+.$A/EA;G1,82,=(+H3$!94;!.-+#%AC>B.?!3G;$&F:?3;:D8?#C;(,D8E=1--1B'63F/:;2%86)<!6&-AHC!8%-EH!1(-4;<C1H/#B%F'*A-B.0,)02918A*G!?D15DE9A?;7B)4>),*:HG98&
@r3166
ATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTG
+
<?H%#6@F:3@7?!<<E*38=F<%>E%+DC1$$<!G+C55&'39&C8
@r3167
TCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCNGATATAGCCTGGTGGTTCAGGNGGCGCATTTTTATTGCTGTGTTGCGNTGGTAATTCTT
+
2'::::D=E6HF+H2FB13@B:+86>1D&E$2#-B3,;4+5ABBF8;??3.5H+67H5EH*."31!8$>2#AF,)/DA*$$!)B*0!%??."'EB?E#@)H47#='27;0%E-?F2#-.?BB>F!H'*15
@r3168
NTTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATCTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTC
+
(>D"!$=?5//?DG9$44F%G7B?C12H="1@-"<D!@&.4?,??,:9>HCD40H(@!<AC1A>)A!6/7:3BH4*)"C'&0!=3B#/G",260#A!=!-A"2)1>(,9>>
@r3169
TGGTTGCTCTGCTGAGCTGCACTATCCCCTTTCTCGTTGT
+
D?"=5G)/E(G*C5ED71A3/'-#9#5<C*$:=#$B9/?D
@r3170
AGGTGAAGGACTCCTTNGGCGGGATGATCCCCATGTTCAGGGGGCN
+
2<5$9@'(C:*@E$121"%&94.6G1'E?24G+.84-=91:B%3>(
@r3171
NANCCTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCNGATACTGCGAGGTGGTTTT
+
&&"*&&!('"%$(+#"'('*#"""+&&#*+!#"*)*)%!!*+!")%(""'!+)$(&!'+&)!!%*#)#)+%!**%'!&*#(&(&'%%%%&')%"'$*!#"+*!&)"++*&!#(#"**!!"*+!
@r3172
GATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACNGAAAAGCCCACTGGACAGTCCGGCACTGANCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATNGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCNGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAANCAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCA
+
AC=*G7%AA#3</!=#261;"-9&=9$D#C5FA#<4,)DD$(#//"H(0:24DC(F272;4?F@/(6'/+=+9D?;=F9!BH2,;<9B*->6DED)0FA8@#:;F7GH7-@DF/2'B#4$.F8$0A7&/DF3,<0*F#3321GE=;C-#!A')$%6"/H;;@=*360@87=%>?9E$3"H3"#C92F.-=C0"+<"0+9@=='GC*<263>01/3.;(979=#;F)(.%2B2+?,B:%B8=4<2&*=%;/C5'=1.$80+GA=#,EBH3;/5=:36<$("()4,#F,.%@&=C).66#A::3"*-?%-=2558(#:8(22#<4"+?;0D)=)4::@C&$(?8--")(6=+8*"G-2&(-:(5.8A6*?"=+#'4?BE7:'G5-,"%3&E&-2&+C>D0(.0&@:;G&G7
@r3173
GAGCGTGTTTATCGGCTACATCGGTACTGACTCGANTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAA
+
=;H7@E,654;CH@D!EE45B!84*3;.04&G>*#>(&<$H!4!?6A7D706'44.$)"1-/:#<H87;#
@r3174
NGCCATCATGAATGCGATGGGCAGCGACTACATCCTTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACT
+
!6B$CE//DC!!F582!"159!('G!'0,$#>7?91F,D)%>$;*(:@7'30=:HF?9%$'DC;!<>D-19A'+348*AGB.0D9?>3AF4==<F4BA@/+:/.
@r3175
GATATTCCCNCCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACG
+
'''+)(!+#"+&)%!%&++)+!&#$"%!*&'")$$$)+&"*$'%$&"
@r3176
NCGTCATCCAGTGTTAGACAATCTGCACCCAGGTGGTGAACGG
+
"$%A=*E4E)#9@>=BGEB+,3!(3.0?1.89?0/#B7C3G!(
@r3177
NTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTG
+
"5?!$8><.24!0:)6&6;#%@*$2*A#&(:8*>%952%B=-,&0!&("#4,#88',(2$('<1C"6;7=@%A<<F2.'C8(HGB
@r3178
GAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATNACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGC
+
204?8FFH-F5>F3=!3++#,G@>:BGF10/)==8)=#",8F)5>?D!))+7/5F914B6;*/@+@<"?AB!"(F#F-099>%=27,;;'C@<D.(G%")/#>98)C
@r3179
CCTCGCTATACATTTCTAANTCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAA
+
A*%.6@0F(910=EF(%*A>!9$?G1#:D)HB37E6>#4+5-"&3&.%1#5!$&7<@H?-!BC3/A:A5=+3:/)$A+"/D<A,<@>)<(>#7
@r3180
ATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCA
+
HF(>%65:0B:8+:8(C@:?2.8#=0GD2.8>*$01?*.1/A4G!84)34G9#0/1A?*<63)+)4!F#
@r3181
TCCCGTTCATCCAGCAGTTCCAGCACAATCGNTGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTC
+
,>/%%)&$35,D$66'&1!<HGHB5>==7HDA'!<HHFA<4B4GFA/41D'3,(*H-:6;,9*$3CED)/D*+6?4A0)=
@r3182
CNCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTT
+
)#:#;@',:!5E2%!H2E@*$271+/78-&-3,<8)E"B<G#=/0F9%7.>H/?9*!-2*(%4A+>".$,52#&-."*&H&5F?4H74-4*%!7EF$9F!8AG
@r3183
ANGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATNAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGNGAGTNAGTT
+
@6H>+&0"G"7<',!A>7'"/>'A#94&5F/<A:$50&AE(;G!//81#,0AH<3F1/(6H72/3BA$5H'9%D"&<
@r3184
AATGCGCGTAGCCCGTCGGNAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTG
+
84@''&7HH-5G3E,#600#/;-74'80>A#!.@!/6%1.F/+<E174>.-@+90&4)%,(7B$@>%$;><2F>3@7!5DEF@&B**,9:9=>=F2B#?;'21%G275A7..B);
@r3185
ATTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCAT
+
%D=.*0$=0.H&2(01"*B&82+4,E,>4>-<(:HE*92,F:2==3
@r3186
CNNACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGA
+
#%$+)(*%)!!"&"$%%"&!!+)'*!*&!(*(+%!#"$+%(''*+%'%(!++#!"$!%$($&*!+)
@r3187
ATGCGCAGCAGCAGAGCGATACNGAAGCGTNACGGCTGAAATNTACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCNCTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGATAANGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGANCGTTGCCAA
+
1-@"&$;:CHC;99,586F.+=*=(#06G=;)G?B*6/7EG@+)75F04<)!3"0;)%(::'6D5%..DD7'0+%&<2=1=$/A:59'8,&8C,*55H2")#C5,$!?H2.AA"53'*AB1-*<9;"&,0+<>7GG8%1:9&??=277*76;A/948B%A2-3(@-9:A=)$DB),3<4*/753@:HH)$?4C"F?@F9:090EFD'GA1&F8%H,*DF>;4AA+)*BD3-/$#;1<BE-?/>=-B'9</:@/*H"0HGA
@r3188
ATATTNACTGGTANTGACCTTNCNNNTGCAACAAATTGATAANCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAAGGTAAAATGATATAAATATCAATAT
+
%*%)%#"&*""#&#"##'')'#!%*"%+$)%(&*$*((*''!$$&&)&&'$%%*$%+%)%"))"!("%'#)(%!(%"''#"&%#*"#++&&)#%(+)!$!#&'$$")#)*"$(*&("
@r3189
AACGAGGGAAAATCCCCTAAAACNACGTTTAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGNGAATCCTCTGACCAGCCAGAAAACGACCTATCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGATAGCAGAAGANCTGNCCG
+
3"-(*!;3,5E4#/D*'58''CE#4!A+%2>'8>'!:,2E<08.G&@>%:*'E@2@=,8=5E#;).,8HD19093)F?.FGC><B(;83<?B3>>)<$@7",<$%8BE8"?/D8?9=*7G96+BG5#4*2*5GD=F#9>-016,;4AE2E:<!"A2.H&8(0@>5+((-F5F;E#;5-?H!"-/7.%.#D22-4C?F=HA.<CHG:5CC7)8),5:.&7'"5";,>@5927&H7&=9#
@r3190
AGGCGGTNTCACATAAAACATTTTGCATCNGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCCACGCG
+
5&07)4@--.1869$G;?D*5#('==C"B-,'+;?&B/0%*.*?'4)G;$&FH.G>36C9B>((-C+?3)6.",%2?<D?@7$2C@C4/%5DD!$EE"67DC=32?;+9.-
@r3191
CATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGT
+
3FA@G9,8D9<(<F=1@/#HE!8+/0FG@1"?>&6A0';H.F$:68.-+<,/
@r3192
CNTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAA
+
"$*+'!!$(+#!'('#'%$**'$!*%'#"#&!*")")!&)(!#("!#"%'"&!%!!$)%&
@r3193
AGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATAT
+
EDFC7E#.%H&7-<9H<!CBF;EG-,!=4+4@G/:()B8G'<
@r3194
TGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGAC
+
5(5<C)//F9&%+770.<9F/:9=$,&/&!*A>B:)"GC/E9%43/D<$B2??7*!+&0!<'E6G-E?FD#%B0D<38%-FD%/8
@r3195
TGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGC
+
?0(F,?.;.#/9/E%53E5.#7%+-@$(,9D:E;15+*6E#,59)%7C0#C?$,&,.F.0/,1/#.&B;5;C4?C4.CF5F"B(HC(19F:=-"E.>6)?+'7G*%3/G>,B>7"F9%A!
@r3196
CACCCTCAGAGAGAGGCTGATCACTATGCAANAACAACTGGAAGGAACCCAGAAGTATATTAANGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCANGCA
+
7>"HD3CC)7$BB08!?'<F8*%AD-@.(+6%#+$!.$"563%##H6@/72/=#$36+D'*"5!76A<-E<C<>-<B!;?;:,9/D4GH10?:$?,5=.5:'7->2=*5
@r3197
TTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGAC
+
C0G7<?>3%D#9G'5&2+';!?35-CA('6?A:G0/D4&-:"+*C-!06>*E*B1>F).B11';B6'E8H9HD1!?"+&5)-!/#3*74$.@66-54D4HH#2$)1E$D.0?)7?(<8A:+)'!C8&8:3/$?#;E;%;:)CH?#".A?E!:9E7G33!52+#7#(.C7<>C+%<312"
@r3198
TACCTACAAAGNCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATG
+
'031G)<;6D).@*0,#(((2<(*3F9,0!?=5#D80GF)+;E46%8E&64)A*H9,:B*FB4&?46?=?
@r3199
CNGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCT
+
*(&%&+'!)#!$)+$$$&(')&(!(!!)#&$!($%""$+(##$%$$!"*!"+%&(*))&)%&
@r3200
NGGTGGCCTGTTCTCCGGAGGTGGACTATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGT
+
#EF<:/71385#6<A0D<$6*=!%95C@$2D1F)B.>47&G&"'&'1=6!;.D.HEG3@)//*0($#@;5G8$E*+A
@r3201
NNCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCA
+
*!@3;'A5-D,.)=H0@333>!4+63(*4B>6,;&D@3,:(>HD=85(1-314;@>;:!-/4F8C;GB;09=4(3;99<,*H
@r3202
CATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGAT
+
8*;!02H,;+%5!DF-B5BB@A-<0/$3.#!;+E2*&D-,<CBF8B!.E*/+9-#:>5?24&7=2C#=6D?+;&E#551)-&F3%-B/1H<*@4*
@r3203
ACCGCTCCNCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGNCGATTTCC
+
@!8)%(DFE<?G7@>H1/4)<+@'F8*F9$<)D0(?++8",;#44//%C%6'@>?&549<@0'=/"3"77*%64'71+871*D4BBG<39:8998*(%!)C8=5*=6D)!2$:<2D,B?<1*/F
@r3204
TACAACTGGCGTAATCATGGCCCTTCGGGGCCNTTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTCGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCG
+
0"?/D4680=(F8A")$BE:%FG';?2F<48G).,-91?)8D;1)2C)D79;9H*H0H*/8$=')BD)B5#H*G!1%;B;)=&A2<E-5B43#>B=@/&(.,2/20*,2@D>0<:/*#5""4$>A=0C;>D0$$4):F#/(B3"&=F08B1-6*/*7!0/+25%28<,A,%0H;2-%E;#&1F%A7G!$D(#)57E-!1#
@r3205
TCAGGCGAGCCAGATGTTTNTGTGCTGGCTGGAAGNGGCCATCGTTCGCCGCGTGGTGACG
+
6F$)!/D+G1G:)8$&.;5926-.36<43G7/F6611-4:)/;978G0%E+8C.>?/1)F7
@r3206
TTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCAC
+
8!-6E,H:'E%#*5=H/2G5G(;$3:$H854G,3664?1H:><'3E.F93@?>1+"&B@2;9@8<?E0',*;80-&>,3;@*0+A83+.90?>'9-#,95HG0'B(H.:G0
@r3207
TAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCCACTTACCGCAGCAANAATAAAGGGAAAGCTCAATAAA
+
2+2*17-$+DCBE>>E8#D>8AG-$<D99?=);-;?4C&'*!<;'0/9GAG0&D9"19B/96:.3;4-'FG9"9F+)8)2"
@r3208
CNNAGAATTAAGGAAAACAGACAGGNTTATTGAGCTTTCCCTTTATTTTTGCTG
+
@-:'"9<G/&4(F1=--3*?8-&$<C+<%('4D3D13G5?5&9#H%0%10&-,4
@r3209
NTAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAG
+
(:&:><3>9A*HG@H84:!>,+@$F<'C>3.3"'4!2'+6F,:<'("-D2D*,&?116#&51F/E-B.B$7'G#C04
@r3210
ATAACTTTCCCCACAACGGAACAACTCTGTCNTTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGC
+
'H%H(E*:H"6$004%5*(<:2+-B@=;F1+@09E1@&8G7$"7<$42&<7'2E7D.1G1:8'0#B:D'9D>AC/",/*-B@/72G#
@r3211
TTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAANTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCT
+
:8=03='5&%>"1.4D@6/<&:/%?!!G7!@@%=+6-5!;@@$!7&HF#F'@=%>CC=#G&,0"(.""D$$-)!2%.#'67$FE,H8'9'6'16A%=?,H%/3?
@r3212
ATANTNNNNCNNGCATNNNCNNNNATTNTGNNCTTNNNCNCNCNANANNNNNTGCNGNNCANNGCGATCAACATTGCACNCCNNNNNGGCAGTGNNANCNNCCTNNNGNNTNGNTNCACNGNTGACTNCCTCNGNNANGNNNNCGNNCNNNCCCANNTANNCCNNNTCNNNTGNTNTNGNNNNAANNTNNNGCNNAGGNCNANGGGNNCAANNAGNNNCCNNNNNTNTNCCTNANTGNGNGGNNTNATNNCNNNCCNTNGNNANTATNAGAGCATCGANCNNGNGNNNTATGTTGTANGNTNNGCTCNGATCNNGATGNTNNANNTNANNANNTNNNN
+
""!$#$#"##""$$$#"#$"!!#"#"!!"$!$"$$!#!#$$"#!#"!$!"!"$"#"#!"$#"#$$$#$##!"$##$!#$""""!"!"#$$$#$#"!!!##$#$!"#!$$"$!$$#$!!"$"!$#"$"!##!#!$$!$!!$!##!!"!##$!$$!$"#!""$##""!$#"$"#!!""!$$!!!"#$"!$#!!#$"#!#!$$#"#"!!""$#$!!!"$!!#"!!$!###!!$###$"$$#"#!!!!"$!$$"#!!!"$"$##!$"!"#$!#$#!#$$$##$$!#"#$!""###$$#!!$#""$#!"!$!$$!#$$#$$$$!""""#####""$"!#"##"
@r3213
CTGATTGACCGGCAGATNATTATGGNCCGCCACGACGATGACCAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTA
+
?3-H@C;+66>-B?3=D5&G>.47/($92$<A%=%/#3<;)39@%*$"#DDH5A*9:G&#3/;!AD0D;<E#C6'.1:57H6$
@r3214
TAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAANATATCCCTTTGGGATTCT
+
;FE"!,!#?02;"-,H663<=;+EH1>H@$,66#&690E<(5:)-2A8#?BE2031;8=,%;.?
@r3215
NTCNCNCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTA
+
&)"!*"+'+"")&**%&"*&%%)!++#%&(%$&$$)&(&"!%!''#)$%$$)+%#+$+$#"#((%$&*%'+"(%%!"%#")(!##$'*!%**+%)*"$&%+"$!''!&+!**"'$)$!"*'#)'))$#"$)(+'')(*!'%)"&$#"%(+*
@r3216
ATAGTCAACACGCACGGTGTTAGATATTTATNCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGA
+
50GB6&CA1E8@$/1)*@5A!=2-%$%!7A"#C'6.7957@54HFE=&**<H;=97@!(-GH$"'*6D23C8G58=BHA>D<-->8)&.7,F;8/H(="A=!418(?F,'HB>-3'=HH!&?',!@4A5!H&.6B.C.-G7
@r3217
ACACCCACGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCNAGATGATAAGCATCCCGGAACAGTGTGTAACANTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGGTGCGGCACGCAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCNCCACGGCAAATCACTCTG
+
('&!%%"+&!!*"'!#')$!##+$''#")&**"!$$)&%(#!'***%"""(+'"(+"*))+$+*)%#*+"!"("%)$*'*$#&('"**!&"&'!%)%%((((*"("&'(&!%")(+&&$"!%*(!#+#)()$&'++*%&+*&!(#$"!!'"*+*("*")%$*%#""**"$&(!*#"(+(#&&*"!(&+)")*)$!*)'#)%!*'&*+"+%(("%$+%)+()'&)++'++
@r3218
GCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTT
+
0G(9-#@CF20)>'F4G/"44'3@/$26H)G&>/D?;8(((#?<'3(*?E?>
@r3219
AGACGATACGTCGAAGTGACCAACTANGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTA
+
7&2B$.,F10(56/0*2*>A#6@-"F/.;0B'$D2A7-:'F*2':<3$-++7/0A%@D90";?A(C&
@r3220
TGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCNCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCG
+
#-F:<CA"&=3=E+CEH%:$51(#&!!;$*:<'@A((GF3GD@F%4-1@$E.1*34A'987C1G6+.F7%4!;14:G0
@r3221
GTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGG
+
H@033)8C?%79)-"847"21:&B:(%A$5%*@:8>9H/)07'
@r3222
CAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACGGATGGTCAGCGTGT
+
>CE@"FE9$$.@B:F=+4'#4(;5;C-:A+5?:3.$H6@12-*,<@*0893?$F#853!1+A)$"6D/B:?!">B6(?C4*
@r3223
TGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCACC
+
,';,08,HC2AF0@C!(--!3$7&"?A*")D$?&#>*E&'0'%G7:E-1&'@#@;D3*5B-GA'*3&H@$/D
@r3224
CAGCAACTGCGTGGACTNCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATT
+
B>;?+1,E(5*G:G#?6=8("D6+08#7HE%,74$/4FG&6">",$$"6)E)&#8D(/D!'/C$(9:.9,
@r3225
AGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCGTCTGCTCAGTGGGAT
+
-H'.$.@D4@0%39=71=BEGA,*<D5,0+=3@9:10*:?3%HG)C?&4,43E1(()!1!*666&1)=,8)6,0#!-7!:
@r3226
NAANNAGNTNAGGGTGTTGCGCTGCTTATGCTCTATAAANTNGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCNGACTTCACCACATTCACCTCAC
+
(**!!*(($%('+$$'")*)$"&!&)&*(%%$%"!#%)$)+"*)(&&%(%+!*("#)+(*%!('"("+'##$!'%&+#$"!$#++*$$#+')+")!!(##(+#'(($
@r3227
AGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCNTATGGCTTCATTTGGATATCAGAGCTATGGCTCNGAAA
+
72B(D9#)1:B61#+54*!CE!7+8C+</$7#=69=A':"@9;D!;$59-B:C$'B,@G%F4*42?)%H+45?:374/1H5D&$-:-06-''*CA)
@r3228
GATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTNTGCTCGTCATAAACATCCCTTACACT
+
!G<?!35C61$8!2&$B>-/E(3DD8*+7EGHHE9D:>30:CGB20)C199((-?.F3D%03-AF)@/G'B0&EA&@6.?D)8=-;0-*$FA(8=@&,G8HE;/A3,4,"',7+:>#6..E5"10C#5B9=+40+"$
@r3229
AAAAAGCCTGATGCAGGTNGCCAGTGAGCATATTGCGCNGCTTCAGGATGCTGCAGATCTGGAAATTGCA
+
(C1$#H'6@+=3HEHBF72-*3;A99E'+<D?4D4158%@5@E7.!2-B*B%@B$8@H5046)C'C>-@?
@r3230
CACCACANAAAGGTCNTNTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATNTTTTCTTT
+
?1,7$F-23!=+6$,,.94E>AAH'=.-&3#A-=<:D5&=)A<F/>H1@.1,D"F!8&G!58E4),"H+02
@r3231
CCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTT
+
G30A*8!24C4+1:@0>';(68$45>#@%;B(EHA"145+(B0&@>$)&%F
@r3232
NGTATGGAACAACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACNAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAA
+
&3,,'/?7(8&.DE(@@,80/@F6,,2;EG-,?D>3"5%)--<;@$2.?8%?/;7+C8**3/5#8E!=):C=#68-$:GD'10(3FA8CG+B1",&G21A,0636C%%;.C1/348&$+EB73A,;;6.>E,.*25='7!A$4H+96=2>+-)B"0G9+=03!*E4:?+(9<D%%:=-!48'&./+G7>H1G36.%!2>;/87H3+%8;$1#@E'6E())#'C9H1B3(>H5&H
@r3233
TTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAA
+
H"07%''A-,1G<'A6'4'*+60F-7A5D*)/'$<@/#/H5:1G/.&-@ECA0+@@40BH4,
@r3234
NGATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTT
+
".?G@-"8H-;5*=83GH#6(&.$,4E@9%=!5B&G+69C6'>3E)/E!96F&:F=B*5E++)#!*/&$;6
@r3235
ATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGAAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGT
+
11$!1=H#,+5$5*=&?&;C($+'781@7H7.<-D<>DD,1A(!$G;6=E%>(!<D7,<1&D"3%2)E8.**DH2+7$0A#9G'+14!%;5A7D8F@H6<=G:8BHD7"%(#%1=!%"7,$82(@H8GF4@'823800#EC:.2;%
@r3236
GTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTA
+
9=GG#FC.!D6/"..0)1."4?CE%%).5:D@>A=8-C5?4%>47A'+(DD7#%F"=GC?(.G4=F*1<)*E;4CG(5E;F,?10!'+.6>(6G'B!@-"<H+H=.1!A2/<
@r3237
TCCTCCGGCGTGGTTAATGCAGCCTCCCCCCGACTGGCAGACACCG
+
&,.9!:7+/.B$2D09>6!EB6&0*AG1D/?$(=1-;!#/1"01DF
@r3238
GAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATT
+
H5/#&5982$?';%0D".,19-7(<A"@)>(@/-B:=&0!-A?+$044+*@=,-H)1+7::H
@r3239
NNCANNATNCNNGNNTANCNNTNNGGNNANCCGTCNNNGCAGCNNNNNGNNNTNNTNNANGNNANNNTNANNNNTNNANCNNCANATNNNCNNNNGCNGNNANNGTCGNGNTNCCNNNNCCNCNNGTTNNNNTCNNANNNNNNGNNNCGTNNGTNNNNNNGNNTNGNNNGNCG
+
!!#$"$"##"$#"$!!#!"$#$$!"""$#!#$#!$$$!$$$!$"!!!"$""!!#"!#!$!!!#$!$!###$$"!$"!!!$"""#!#!"!!!!!#!$$#"!!$$#$$$#"###"#$!$"$$#"$"$!"$"!!"#"#"#!#!!"$#!"#"!$"!$""!!#!##$##!$!"#!"#!
@r3240
CCNTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTNTGTTGAACAAAACTTTTTCCCGATG
+
''+#!!)#%"%!&"(%!)&($##&*$!!!&$&&%$)*!+')")&$&**))!&*'(!)%*!%'"'$'*!#%!#'!))"'*%$$($#""'"#&")%*%+'($
@r3241
CCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAANACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAG
+
HG%<!0/#<";EA5E!.<,A2"7.2=#01%:&?C,D88"'*1&4*F<347>)>0:"H=)5:3E-.#@CE34&*@H-/2%,&@'7=0&C&0'"?F9.H;?C.#)*"B%3?"H01G<,?E-(2*?/
@r3242
GCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGA
+
5A=.56C<8?G@2?75);<*A@0*3*2=C(:B*5#G)2430&;17375GE55)3#?D3%E59/!7+@0E9A33$=6-H$5AA20
@r3243
GTGCATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGC
+
$((76*6<,6%112%3&8%7?*H;;"GD?#H)G%/?H6(89-*4C7337>(!GA34(+E0C$&8+1/!";"4*BC*H7>G,'D(91*+*%;F,-)F6$D*0#<29(7-@%4"B,
@r3244
GAGANNNNNNAATANGANNCCCCGTGNNNCNANNANNNNNACNCCATNNACNNGCTTATANCCNGNATNNCCGCN
+
"""#$!$#"$##$""##!$#""#$"$"!$$"$$$$#$#!"##"#""$#!#!!"###$#"$#!""$""$#!$##"!
@r3245
TNNNAACANNTTGAAANCNCATANNTNATNCGTACNCTCTTAAACGCAATTG
+
&#%#!(&&"(%!*(*'"$$')%$%&*"%)!$$(&&"&!)+%$&)('*#)'&(
@r3246
GTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGT
+
/>$7+G&D'G43=>(66!3C*)0>%!+2;6$C!!H"5HHF)46=+!(.@+)9)7GD-)551C"*/D#3'84#%,873'5:#?;#F<!9'5BH*?F.%905%5<(?@,$G>F8+=)0&=698093<
@r3247
CATCAAACTGCTCGTTTTCATAGATGATGCGGGACCAGCC
+
DH;H3$-D,!+);3:&+*(./2-@#@5&53>3!$A<CF.;
@r3248
CTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATAATCTCCATAAAACAAAACCCGCCGTAGCGAG
+
'26>,*&@C/&52./&*+7H/C9#*(916"'3'-0F?5.?;5%%@6/;"*>&;>">A825;80*6<,(B-D-%,3=B.1@$+E9)81+&
@r3249
TGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAA
+
A9#=:E4#;'!0=D'G:2-5"#(E:.8/!(6/"+()A6G'>3%//&8%,D-"7?'%E7F.:?"?9#4*-.!$B05#:+>88CBH0*(@>38'>@!#>94@?>:7E
@r3250
CACATCGAATACGTTGTCCTGCCGCNGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAA
+
?2/<7"*-EG7*=>)F3E+8.G,8(A41D!1=%A@'>DG*B+/="#F'=%<2/":-E"4F3
@r3251
AAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGNCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTANTGTGGAAGACGCCA
+
7DC4=6:(B0-$#-@.&--5-A&B11D*)9-FH)0,*>?(""7*3F.H?".5?7=$57&,0&:*%>1-0,=A=.H>$8"+==&99+))#F5?2$$C53&H-%/<3=0"$8%&++7364%4*."#@@0")8C$G,(*:BD0@!C;7>/6
@r3252
TCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGAGCCAGCGGATTATCACCATACTGTTCCTTCAGGCGCTGTNCCGT
+
B!EA;0,A3'E=1:2)FH/-HB)6'(;A47@6*%=@8&#23>7%"H+48777>!236*EC-A/4.E2;34F5B"4($-*.#%?&50':6;)B;('E?!HE31<B&:
@r3253
AGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCC
+
%)>4$BC=B&?31/CGC8*"@;8%-%C9%7*2.1HF*G+55#))CG??!
@r3254
CAATTTTCAGACATTAGCCTNCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGNCTCTGAACAAGGTCACCAATGCTGAGATANCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGG
+
",%FG4,0:+--83BHE;.H/F00B&@/6F&A!(=!58$$,-58:+&&.4*!:C!2*-A5(H>D7-B.3?"@@-4*2&>G7F)-=3.>8@8'8@C1<?6-/*+#40.<C&7C;=.<..35%)')E<1F),E9.-=5>2;??;5/)&;9$()$H;BB*E4H?/82>5B>3
@r3255
GACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTC
+
)H26.$-+,8E03)&35;/>==-12:9)B;$0EE@$2)50H<1;&-?%H7@<;(>4:<DG
@r3256
GCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAG
+
.;=+A#>>+!96!9>C;>G!3#C6'8>/!3E;,<1(?@"%.2E:"-;
@r3257
GCGNATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTT
+
AG'",61.!(4B<6A))-"2.#D(D24:&0-G,;34@&9=
@r3258
CCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCNGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCNCCTGCACGCCGACCAGTGCCGTGTTC
+
(&6?7/6B%+:-.&,4"4BA(A7%"+2.*D24!7!'-C87&%"*2>/.><H9+@3@G3&1>C6#(3!$G*>(0+94BA%98&<?=B#,E"<%-GE0<@/'9';#@0";'2BB7./F":<!D"(B'%,,.CEG:=C4:B(9%"
@r3259
GCCAATATCTAAGTAACTAGATNAGANGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGC
+
:?C$-5&&/903'%"?,%"-8:;EGG>!D)$(@:!0"FD@E,0*%!5++DF(=:-4?DC,)41%BD@!>-:<$183..8?D)&#D#',"/
@r3260
TNACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTANGACCCNCNTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGANTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTAGGGAGCAATGGCGATGACGCATCCTCACGATAATNTGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCNTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATANTAAACGAGGGGCTGTATG
+
$(&+&')#(*"&')"(+$'$((!+#'+++&$("#!"%!+#!)''"+**$($()!&("'!+'++!("!%))#!+'%&)#&&*'+(#*'%$(*))%"%*+**'*#""+&((*#!('*$$+"$#(%%!#")"$")+%!&$%"&'"'$($(&!)&)*'$*'##!!&)"(#'%'"!%*$*&"('"!+#*!("#!#+$"'")*'*#$+#!(!+!%(!'"+%#*#!&&&'"()!$*!!$!(&!*%%)($(*)"$+&%!&!%$*&!'%&'()*$%&($*#$'*$+"%#&(+'*&)"&)"!#%#&"**&+$'+#'))"**#%')!%#)("&&!!'$$(%(+#$+%&$+$'#!&'$!*#%*"!'(!"**
@r3261
GCTGGTTNCCAACCTGTATCAGANCATGCGGGCCAATGCGCTTACTGATGCGGNATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCG
+
8G:1>6E<-&CD,F51+#18);-E-<;@=;1F7<&4C=1),D155?*(D2=6-,4)80!'B:,=5""GE$3*#(F@3#.?22HF.71:)5@1:,"F?7=-$":4#(=G?1*!"6%E#9!)-8%HH2.;5@6@B">7(;AF%+:3C,?FF&C0?,1B3.3'7<48<0&3+1FEE>6E=;=$*&@,$-.
@r3262
CCTTTTACTCCTCCTNAAGAACAACCTGACCCAGCAAAAGGTACNNGATACTTTTATATTGGACTCAAG
+
EA>)/-(5<-&(&9(-&)24<$B1<2>%+>@,#FE8@7#9.)CB=734*:.AD$A6?(D>:;>'>!;+C
@r3263
ACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAA
+
,DA*//5"5&D5@@/=E<50'74+<<G+%7HD-F22>=/#4&.97B9#C.=H'!5C=!01<F1)0A=::9':CG8#4%A=.",01
@r3264
TGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGT
+
C;C/AA#-9.+1(++F$"':9?GD2(92157"D/-)8<!=!4!781AA81!/F>!:8=-).9*C0FC2H5@<F9$9"4*!.4,C?*!!(;2-1&0*1F>"+G5@(%1C:+03/70BE0#.#5$/"D3#%CD2HF./3G56&*/25$#*1#"47GF!27+$
@r3265
CTGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCC
+
""*"85-0A0/D9GC9C$8)"7(G6,3<B'?9/1!>'8$69>->'2536A@,(,+'2!C',0"-HA04.G(;$:810GC"G@5B'E)G",#?AB73>6)+8E!&$3G;9%.88'AB>>9!%G).G"70481/,?E275.@.,-;
@r3266
GNATCTCNTGNNACCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTA
+
)""*'#$"##"$)$&+'(%+*'##'##**((#%#"+#$**&%++'#!"%(('&+!#)*+$+&'(!&(*'##*+$&+((!*!!**"
@r3267
NAANNCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGC
+
!#"&(*#*++&)*"#%!"$'(()!!'*+!$**!+'*+++#&#**((
@r3268
GCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAG
+
.?ED"H1>99F&+BF-=?;4.(GA@.F%F7=F;@<>++527=5)+:;>?4DB7
@r3269
TTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGT
+
+EA80;>4C*%&1/(*;E<3,+6@G'(H53H-DH@"!+B6,><14+-5C<+;3
@r3270
TTANAAGATGACCATCNACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCATGCCTTTTTATTTGGGGGAGAGGGAACTCATG
+
/14./<4*#'>?(/>-;7D!A/D4F)8B'2)?G91'<D@)'&28A4@,>+&-1*1BF?G$!21EF.&'.$/='<GF0'3H@*..>77
@r3271
NCNGTGGGACTTGTTCAATGACACNTCAGCAGGANAACGCCCTTCGCAGCATTGCTCGTCAGNCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACG
+
!!%+&*+'*+#('**'*+'$%"$+$*"*")+'#&%'"#(!#&)#%!'&%!##*#'!'%!"$!%*)('+"*""'*"&+*#)""'%%#&!('*$%!!'*&*#&"&!(**"**'&
@r3272
GATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTANCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGNGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAACGANGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAAAACGACGNCAGAACCCTGTTTGAATTCACTTCCGGCGTGAAT
+
+"*'("$+'$$+#%)*$"'#!)!'!%$**!(+)"#('%*%%+*''&!'$(!#*&&"%%(*"$'"*)%&&**#())("&!)+)+")!)(&!'+(+)!$"+*+"*"%!(&&*(%'!$&!%)(+)+$%)$()*+%&#(&+'"+(!"%%++&$%%($%)'#$&(*&&('*%&"+(#%$!&&#$*#'#%$"(#)'"(#)$#%*'*&&$(#++*('!)+#&"+*''(+)#$"$!+'!"!&)"$'##%!%+$)'+((('&'"%!!&!#%)&())(+)(*'&!'()!+')'*!"&$+($$+$'(!%&$*+%$!$$*#''&&)$$'*!($)%(%!!#"#'%%+#(&""++%%()"!)%#"'"$+*$"**!#*$+&#%$""+%&#+*#"&!$)&%$#%!&)&*+)*'("%!(
@r3273
CGTGTGTTAAATGGTTTGCNAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCGGGATTCAGTGATTTAACTATACCTTTTGAG
+
71F?7/(53'C@#EA:H?B<%E"=1,%@H.G3<GC)=<3>2D+-=B!>%C)(#2.G&D:9<,B"BDD-79#=4:>4E2F=91"2D9<5:H@5#8'G
@r3274
CGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTNCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGNGCAGACGAGCGTTCCGCACGAGATACATGGTA
+
-23?)#60E!$=D),;D(49-F?E#'&.12)""8-$3E#D2')7C()4:<E4!A62F;'-4(-G"B+#F2E0=:G:7>@9%E,)C2A%.614'(4$,<4H#/73H$6)'=>"&D*->;(A&,;/<+5.%C#!(H+0=<GF'-"&3*/F(*'><84@C5
@r3275
CCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCGTACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATNTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGC
+
6=,!G3=!.'G%GD'EE"+EE*&G+-:E'4E@2,7B"5;5=.+!-$F6/7D.B6;;5'<2%4-D9%@>%<6F'&%-%/CH:D%/G<:<,&8(#8!5D"E4*H<7728/C=$B)0GF!E+@>5.BCC5B.52(@EAH!H.F@*@(#C80H-G&:%$F)EG4'!*$A5+;5(#.3:F*DE6+)%7)+3.34DH6;F3=H@FA%'63F0(*)G86#<.5$%@E/<:A.91D.B?3"*,"C;FH+A4AB7<4+"%8:GF-F>4C)-<#)<>%(D;==51$+F@7-.12?#;$<9@-3<!):G$4BF*4+FF;G,A%9<C.>GBH9,%4:C=F1(>6>%6G@:H+E:(;>,@1=!)C<*:
@r3276
GACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCNGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTNAGCGTGGTGCTCTGCCCTTTCAGCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTG
+
8B9*B7$GD=0/$@=$2#0<-@$7<267;'2>=1$*-D"9&206?5$E1=:$$.+-?!54DE5D2.*692)B$D1G6.HB5+;)G%8D1.(*)C-3%1)G69@#0E;.E$2H9'57B.<;%,<"59;5C)'=3#;87"B24/@'0)9$6@D@4,6:72<9<A)2>7E:(;C+.G4#:*E><),AA"+*!DG8(%$$*B=<AH<19;E0-9E!"(?6,='D=1C9"G;@1A8A@!(!DH&3A@(?1(7&@D5:$E)!$G2%22/+=*DB1/CAFE<>"#<H'$H.>)0+/0F6=&,G(0B+201,%6368D?4(#''&76@:/@4:G<.E#0%+-A#+$**7HH
@r3277
CTTTTTTTTGTTTCTTCCGCCTCCCGGATTCGGAACAGTTTTTCTGCTTCCGTAT
+
,62"9?!D10&89&1!+%(BD"E>'#7BF+$?DFB!=.=B($7$049'3D=F4B0
@r3278
GGAAANTGATCCGAAAAAAACAGCGGCAGTCNTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTG
+
,%*3'(C7+<0,3-;77.&H+EFDFC3;3%B@)<1?@'5@%6C>!6=7=?!"-)(-=;B2"3<2.
@r3279
AGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCNTATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCC
+
/:4.896+A'?+E=*;H('4&(FH!-;G>0!%9#-!.$(;8,&?1-%<H@9*=A75-:2,?$(6&6:;7G$G/D*"@;D2(A1E?(*1"BE%8$4+%E9B')-;D>&!</H''.9F--530.3$C);E0D>B)1'7B##'+5*9BC2?&8!/!>7<#*E
@r3280
AGACCCANCCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACCGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGT
+
29,!>*:E#,)-<)"77B),0>D">G$>1H)*.$A0:<-9B'(E1ED1(>C=9:HB35B1(8F6.=--%'=C>D&;'7&.@E=@C9,/E;B4=5#<'
@r3281
NCANGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGT
+
#*#$+!*&))"$+!!++"*&'("'$(!'+)$)(#++&%$*)'*)#""!!
@r3282
CACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGANAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCC
+
>G4:@%>7C*HEG0561?(B*%1877=-5"64(4+2#32@#3*?C%&5&/7$=203".<C(;2!$>+EBEBD5'3%,%93,$G3<'#G</!G6>?G2&'B4;%838>59>FG#.F;+899C"'C#&@F;)(F9/:/9;;&??//F3:?)0E*70/08G%/9FGEFC@1<:%()/,9(
@r3283
CTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCG
+
<,7G'!12;",H>4'53B,EA@,C?.56B*#D?2;6)0<!D;2G-=9-=$(,!45=@F2,!"!
@r3284
GAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGC
+
/33/'F7&FDG2@"$+,@)<?!@H6A/$*(H14!9CF"F&9$7>+2A><C3.40<8&8&@"&58.!<814.,?#*0:6&B*>,6,EFDCG
@r3285
AACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTC
+
12H0%62;!B;&E'(B!<45B=;;=&+G0..17'.23?=*#5(.8G/HDG<(G*/+<;%%DGC/4*9+'84#H+==5/1E==)B$3
@r3286
AGGCTGCCAGCGACGAGAGGANAAAACGGACCGCGTTTGCCGGAACNGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGG
+
%+*'#")!!+('""$+%*%!+*)!"$+&+&&)$%')&+&)*$#!+&#'*$'%(!+$*((&)"#&#)$)')#(!+'+"))(()""$)#
@r3287
TCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAANGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATTAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAA
+
E7%#26".5('(C0G@+>F3".33.*5<&$;62)F<1?#6>C)@E7B&6AH"$>A)7-*'-*E,/D?*2G4+5<%8)6,.$,2FG&,416%;&?0@8?A6%D2;=(##'72A>HB4,&-+=*+?EA93=)=A(3?B4)EC(0,F0-.4*'F/B72#5?)@+BA%$'=1?2GD>D-A08B54-:;,
@r3288
CGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCG
+
:'!B4;BB3%E-A(1?$(CH.7%..-2F?#"753H6(*+-@@/57A8G7D0H@:?56H>'
@r3289
CTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCGAGCGCGTTCAGGCG
+
:;0&&(?;E5;:2E-$EE+">G8"*':+5@462(5%(%#(,/"#1<.)@H8,&:%)&)>2>>0B,DA4)E'G2FE!CE!:*5+!8-;4A?)>=.(AC116(*$(*"2,="!(!?(
@r3290
CAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCCCAA
+
&D</E7.*8>"HH.<-=D="3+<)+(#@,'E7,*/$B-:'8GC-!-;2/?0
@r3291
CCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGNTAACGTCACCACGCGGCGAACGATGGCCTCT
+
'&@!BFD3?&)#&)6(AB(?)B,1;6A?G8&'&3').FHD)*15;5#'CF@CCB?&(F,)#.6;
@r3292
TGNAAATACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTCAAGATACTGCTCCTCCCCGCAATGCAGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCC
+
(((%%##)*"'&&(#+!*!''($'$!+$#%"#($*)$''!&+%"#!*%!+!&#!'($)+*%$*"%+%+&"%($*!!!$)!''!%&"$+()+!+*$%&)$'("'$$%($''')&$&"$*(&$+!"&#("!)&%%!*)")+()("$&)%)#+'$!"!!*"#'+#&#)"+$&+#'*()+%%$!"$#+#(#$")#$#)")&'"!"%%$!)+&'$#%*&"&"%&)'!%'&%+""####+'$+"$"#'$"'#())*(#$"%$*'')+*'$&"+*%+%")+"+(*#*('%
@r3293
NATAACGATCCTATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTG
+
$+'&')*$+)%(*&"#*$'"%(+$))+*!!"&#$###(*$&"&!"+$'&"''("%'*)$)$+&"%"&(*%#"($*!'*(%"""'&'&'+'*+%#)#%+*%())%
@r3294
GTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATNANCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATNCCTGAGCGGTTGTACAAGTTCCGCAATAACGTCGG
+
6#8;>..(<?;9!3@'=.&$%8%G7G8)*)>5A=#)*BC4-A"</;/"+B8A$E$?*C!9AC)%G*$(>.C>3B5'C!/(#!C?C/!/!BA'%.;E?'0$F.>+,$/'DHG#!9<AB;%C86)
@r3295
GGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGNCTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACNAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAACGG
+
-C*6(&>A*7>A46G"$)70?8$$2C:EG7F$?=>?=:DE%A(;/4"9A8(HDG#=A-F-2='.1<.(1:;:54685-"F,6?(%0=;;9<?3G7.932E80E3/(3.=0CAC0=9G&8C6!4$"6ACA4D$%!-C98%<93<!C!@D:875'EE$*88$$A1///0'3F%0@+&)#+3B
@r3296
GTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCC
+
83HE7'2G!/5@8)/6A1)F*?#+72D-+.,E='.C/!$'%"57D
@r3297
AGGTGGTGAACTGATGCAGGATATCCTGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTG
+
0A)=HF@>'1A#C#!%#)@AE:#=D'4B;!1HB;<.8#3?G%B)%A3CGBC<<1A$5"B$FG%()';1!9H>@G2@;C0:5")!<)41'-HF?%$3<
@r3298
ANGTNGANAGTNACTAACGGGTCTTGTTCGATTAACAGCCGCAGAAACTCTTCNAGGTCACCAGT
+
#%'%")%#*$(!+!("&'#&#')(%#(""$"*#%*$%('#$('+')*#&!"+&)*'#'#$#!)**
@r3299
AGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCT
+
A*='<4A#/B8C12"=43D:!5DF-3FC55G0#B%+99B#=$+4-=G(E
@r3300
AGCGGCCTGAATGGCTGTNCCGCCTGNCGCGGATGCGCCGCCACCAACAGCTCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGTACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCACATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCT
+
''+(!%(&+!%*$&*"#*+$(+'+'$"'"!!(+$$%(&"*'&"()(&*(&+#"'%!+!%(&"#+%$!(%%#+(*&'%#&%($*+!)*$*""(($)$$'$$()*#+((#&%+#*"")&'+)*++!+$'"(&#'##$)+*((&!$!&&#'&"((#+(!+(+#%")(%()!%)$(*&'%(*'+&)*#&%$"$+)(&"$()+*(("%((%+*+)*+&"$%'!$%#+"&**'$&#"%!+)'!%!"*$#'"%+!+$$%&*""#
@r3301
GGGATGGNTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCA
+
59***/EG+/)3!GD5"4#A!>,F19E$C0!+G.43FH?7*4$A1)4$7(2;1<CH<G0
@r3302
AAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGNTAACTTT
+
C0"(F**EH*1A#?(6=9G"<*"6,2$+8H0<<EB6$$)E3H68A#$:;>6F+&D":>6864,.=(>"D))4#+E-B#E?-8GHF+/,=2<G073007?&H<"9!4C9#1%-7(D/=G&FGE:A
@r3303
TCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTC
+
4FB'"55-@?2E8F5;"/89.</3&.(2*@3<H@)1(BD181!2C(.B)**9???
@r3304
CCATCACCGTGTATGAAGATTCACAACCGNGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGNCGTCTTGAACTGATGGTGGAAGAGG
+
7<:!&8$:-?/$;604*,?+G'&(A)<H&(;3G@#2G'05*9#,E329(GB'<()1!'D@""(432=8C0H#/5)<4#!($*!B86@%E19B6$""659#3;4E'<11A-<#B@:)"
@r3305
ANAANCATGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGTCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCNTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAANACCTGGGCAAAGCNGTGTCCTATAAGGGGATGTATGGCGATG
+
$"%$(''*(+$'%*#'+&(*&("'&&)#&"%#+)#$%)%)'+"+++!+*('"+$**"#!!&*++#%$*!((")%$"!)()"''!%)*&!()"()$$()$'%&(&+"!&("'))$#("+("+)++''(%)*%#'$"$)!&%&&+&"('!*')%()))%%'*%!)!')'&")()%#(")%!#!(&%%$%"++(%#")'#%%$()%('"%""!#)("+#($#'#*(+&#&)*)&
@r3306
GTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAAGANTTCTTCAGGCTTAACCATGC
+
DB9F(6%/4H)*+</2)G83C#H</%2679,'54"B1#:#B!%?48!%@%%9F;=BA8H/FE6%CG03+
@r3307
GCNGGTNGAGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCG
+
')$!%*$*#$+%'%&*)!%("$*'+#"+%!"*)$)(#$#+$!$$'&('&$&#%%%$*%"''
@r3308
CGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGNACTTGTCACGCTTNCTCCACTCCGTGCCGCC
+
'&+!$"())+%&%(&)#%$")")+*'$!!%#!!")+*#%%)')#)''+("%$!"##!$""(&+''*+"+
@r3309
GGAAACTCACGCCCTTCACCACCTTCGGTGNGTCCCATCGCGCCAGCACCTGATATNCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCG
+
:&+.B#)47)/5:5*6&C&>.03+61"536%%B%>#&1'D0)&-F02A#2<)%;7G9'+A>51:?H,50.$*6*9<,;C-7/(+6G>(E%:47(.-2."
@r3310
CAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGAGTCATGACCCTGCCN
+
<B+$$=(!*>/.225<;4E.H9=4)0.#2A7/%>'E*G+B,G(,'1,C'!/@$4#F@91'&;;=1;0FHFG277:0+(DD-"/C.5>A'C'@G9%DG5,5>!34=4C+C==@(/B,.-4%1:*EG<.4'.35%44!D08<>+F
@r3311
GGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCNACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTATCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCGGGAACACGTCGTTCATGAATATCT
+
9>.&)&5823=,"$A9</B(,64$E,91-%3(43,G#FH()'<2870&@"!54&?@8>-,(H''A*,0+F;3'9?2.GG;%HG*<#:&)54A-=%&9GHE;F!++%99'A=6D,H.#,4DC2/?)E=2#>8A?'/(!@#8?:1H$//H.&%(=8@&+$>)$C"5"A&?B46,2185,G#H?<1*40<,95<@8<,GE()$:D)<?'5#;1"?1)-8,9C?!/<-0A9<0C/0E8G:&4:A=//F&B$2F*'ECH:-;F!A6;>AA?<6##%E@4$5>(GCC**($5$.$'2<.4;3638(((8C>H&?>.'B501"2:
@r3312
NGNGNGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCNACCGA
+
#'$!"'+&'$(#$"$!$))+&"*&!!(*$)'"!($&!"!%("!)$!($(""+&)'&(
@r3313
TNAGNTGATNTCCCNTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGNAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACATGCGATCNGCNACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGCGTCT
+
"$")!*')'#*$)%#&)++$(%*%&'&&&&%")("%"(*&%#!)#)"+!!#+"*'#$'%#&$'*&!!!$**!+&%"'+%((#!*###$(')!*%#!'#()&*+"$#%%*)))(!%*#*++(!"!("!%*"(!(!'#&'%")#+!("!#+#&"'+(+++*%*#$
@r3314
GNCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGT
+
$"989@><C()=A&;0"?A'5;G3,2@E680;6$$#C9?)(7G7?6@<1)$<&1=@6=?E8<)%B#:)2;5@
@r3315
NGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCG
+
"BAC>*EB&EE*(/1,8);*H7>1?(&$E1.8'8=E937*?.>"1.AAH'=((.>H$$G;G:!:BB.+F00&E,(6+0="A1A28C>G'
@r3316
AAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTN
+
GH"+15@F,.F9@4.$/1."D40$(.HA3A*C@H(!E+.H2>*6#;<?1C$&(>/<A"?C/-:G633+<<*CG")2*-F(+)!2<.,7F9.;64G9E+H*,1/.-@0$-3*D.F?;,-#,:AC.=*C0+"60@G&B+6&8
@r3317
AAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATA
+
,(D*5C"@7>A=H*C;CAA#7)33:00AB$*>6,(<'H/*6+&!*>HB)'/*G<7G%:8&/48422/%1H2
@r3318
CGATTTGGTGCCGTAATCGAAACTGCCTGTTGNTTTCGTCC
+
++"&(($%(%($""((%")''')!&)!!'(#!)&)'%)#)*
@r3319
ACTAANCNNTANNTTTGCCCACCTGCCTTTTAAAACATTCCNGTATATCACTTTTC
+
'"$(("'%())!#+%&!#$#(($"+%(*!++)#!+(&+*!&#)!$'%#(%)!*"#$
@r3320
ACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCG
+
3.194338"85<-4'GH0).'#22/561;-E=D;%%D++72!'(?5F&/A8=7@B*):G31+43;$"#*;5*);D2E060>(#::.)&/,>04$B,G@7'F@$15&C2<@H&GE>;@5;6@7@6%&7A?-$68+*EC5,>"5/*5C$/)71G&
@r3321
GATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGA
+
(4)&16,(8.C$#</>/4+-#"A0+B<09>$+(4B=42+@&BB%!HC</@+5D<>8;H/G14.D4=5!",8GF2/(<!+'B@1'(5D6E91$0'/%%H%@7&'5&88>-;F91=9=1+?B(,AH0
@r3322
GGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGNAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCA
+
=6)2"6D&*)C8(%D.G?-&4->E&%1E"H*A&*>+,0F/D&B;5&AGE9+<GE#%)0=!04-#1/C"+4473'"&E$<?063>".'90>6H/D2)=%>G4
@r3323
CACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCNAAAGAGGCAGCAAAANCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAANGGCGGCAGAAAATTCT
+
+++"!"(%&*%!*!''%$"*)&)!%*!%)#+&!%($$++%!&!(*(!!&#*&('*&')!!+'#)!)""+)#+(*$"'+%$!%+((*)($"##)&")*#!(**+"%+)#+(("'%%"*(#&'#&'%*#"'*&&%'!#&+&+"('#&$!$#(+'%(
@r3324
TGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAANTGGGGAAGTGAGTAATGAAATTAT
+
+'!*#()"$+%*(($"&*'$)))!()*!'&%#$!&'))'$%$#!%')(&)$$+#!(")#)$')*(+'+((&)&++!$%)%"%""$'"++#$($##%)&)"#(#)"!(*$(#'(
@r3325
TCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCNCGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTATTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTNATCATCGCAGATTTCNATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGNGTTTCC
+
)?DB3$(%$?H?916B41"-1>@#>;G,B?);)9@BC/-$&!D(2616,*B!)1<5'/)A?>=4<*%E9EC9C12D1G+=H+!;"8G!#:>3()21*34A+:E791@&2>,-=@041987H.!86D!-.4'7H'E+<;&"A>G:A7'<%)?9-,60-)(@;,97"7@F&!B;':<4AF:87?HE&'5F?$6A8@56-H(()8<;!#>/=9E(C172H:6+'$8F2(*GFD6//@/,G4@G*$G$A.*:8AF973.@!G<4FF$$B>47>",<>E5E<F&$*%!6B6#%B!4>!G$=$)-EBG).H0:,CG?)2'A.*F4C=5?&-(<D7(C*?01G6
@r3326
GCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTC
+
$&%+&&$#&+**+(&+*#%&%$++*(*))"$+)"%&$&*$
@r3327
AAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGTCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCG
+
#4>5@G,%=0?$<DG"*AHH&>C=!''/%1%!%2FE.!,D?=B+=;@/F-'4A@F"4D3--:1$@7=?6@D%2%*.HH&6$.2!!%&)"/493:%0+:7F33!3+=&-6?6;6@;2,F'E5GG8G&(%>#/(G:"&='68')%2$:89@:G@E%.+8<
@r3328
GCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATNTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAA
+
#(,'0$8.>2+(>E+"*C5C.&<+D,2&7:)7=)'/E8@/@)?(&5<183$3+<4/%E(@?;B2&D;G6?8$C2,<&;BGG:E=;295&@-8G8=,G@?*C!6-F(0.636H9440&9,?443@%;=?G!<.=>=CA*$*=@:><#H
@r3329
GTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCANGAGAAGCAATAAA
+
G5,1+DBG<"%G:#A=AH<8<+7<&=933%(>HH$=#.E/!,((<@'!>F
@r3330
ACAGAGCTCTTCNTCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACNGCAACGTTTCATCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATA
+
:.*#0@)3&3890HA'365%B=-02,<8.-E2?>1=>H1''4B>94')6@/@/6"!*(.1*/!7B+;@HB#="F#7A%?<C<?G5<*,<0(6.#D%57G&CDB&'#(&)$F0(/.?%:7=8!"*#1%A.A:9).AEB*:1#6B/E$(B:'@@02&D0!.9H!FBB=9;&$0);-A?#'=/H<#/-+,6
@r3331
CCATGGTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACATCGGATCAAACTTAAATTTCTGCTCATTTGCCGCNAGC
+
'("!+(*+!!'&")")(#**+"*!$)%!)''&%"%#"()**!#"$"*#%!&#$&&%++&()"))($#'$&)+*+$"('&(+*)%+&*!'")$!!""$&))+!&*!&$!&)!*!!+"&#+(!&&'$
@r3332
ACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCATTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCT
+
7FC'9.A+71EC9-=H,GF=@-CC63%<3(9%2GB0<013%-F)@>88;;+3$.0F9<1+?89HE0&.G6=;(!3+<0//:1"$5,;C7)?4@HBF-#7*+-)0*;(89?22('G,@DDH#95E:#6'F;1:&;',*919
@r3333
ACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAA
+
0)0,02#*3C3A58,")A+8E*3)@B>&."H6??@7H;7BF1>@(A8:'9:HA
@r3334
CTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGGACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACANATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTA
+
;?"%#EHA5<-3*7G;D7AB8*'<'0'&,%.9$88;9,'?>6<=;E/4)/6F-?GD7:4,E:.3/>?.H/H3>2.&;=3-5<F&+>'2%!G@D6E%'/E&ED<92<13862#,$72CA-)E6!0@1'HD&>004&,,@!'9)"A2B!*.%!:&H-#(*:#A&.5+9CE8"6)&82#6)$G4@F7$1;"7'!904H;=&8)>%$DH+."<G@<
@r3335
NNCGNAATCGCACTTACGGCCAATCCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCT
+
(")&!+&)!"'"&%&%!+%+%)%(+&%)#&#$&#%%'!&'%$)$*!!)'!(#%)'$'$%'(#))!*"&(&
@r3336
CTGGAAGCGCGTGTGTATTGCTCATAATAATTGCATGAGTTGCCCATCGATAAGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTT
+
(5&/D%9:<.FH0FA:!GE6E>",,ED>720#9C7-:=>=+()"&41=!'9<=74/-C1@-(F,AE=DED68>H7DG@"@!7'%G<4%-D4C&H+G4+3+:)A4H>;%A
@r3337
CTTCCGCGAAACGTCAGCGGAAGCACCACTATCTNGCGATCAAAAGGATGGT
+
DA,7@#!.78AB:C<-5=>?4:6++1=1<@5@0,G0-,(.D=BDH::)B?#5
@r3338
GTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCG
+
;C4D!$8%@A&59@@8+4H='GF07>;</=8$+-#@'#1-35
@r3339
CGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTNTGTGTCCTGAAAATAAC
+
?4G9C7;+FC6G#2$-(&=;D*//C=<90FC:<2,C*E/#+!57$%-:A,F1/<)F"=(
@r3340
GGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGNGCACTCTTTCTCGTAGGTACTCANTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGG
+
/*-"%#*@/$&G0B6,@E6*9,1?3??"E$D,5B<-001')0!)B;E"&<B4,#)(CF@"&.-(B,(E.AHD0:?=-.H8+C<@,E.:$8-:#7'/C07B($-6A&;-9DA/=FH%$.&!FFCF(A*$.%"'%<G(<$$6'9)*(D8G/7.=%:)4$6D5%<)8F,+4-7D3.GDH>)'34"D-@>42>6/<586F);./*8;%6;!CGC=9<CFCB=-#/>&";<<*&.0=(/2.*);#.F-)6H#>$2A(E*&:<2'@DFAA'B;=>86%9-3&B4@!C%FC""1(C,D?#%09,420<,1+4$5.G<'6B'1"7.+72!/:.()>F'D95=%?(DB&:%9-!)&;8)5)3-.3(6B251#.49*"+C%'&6$?FA(4)E*(30+?D/%,9CA
@r3341
NTGTTCAGGGGGCTTGCCGGTGCGANCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGT
+
">,.?&),-4;.5EH:F):<1,?.E-CF0A6H1B5<,"+4"*-;B"$,!2=$GC,A;0#5C<2=$+(F&G(9+E1.8=+6E5<<:6F".95!5A8?H9.7*BA=@"0G+30=
@r3342
AAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATANCGTGTCGGCGGAGCAGAT
+
:84&&&D#+<@=<E4G.7:(G316HDC>$3?1>?$36$'10$:!9((9HB3A6=,A0@H8!E+4?H'FEH2<B(4";9C5=:9.2
@r3343
CAACGNTGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGNCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACC
+
*)&%$&&&#%*&&+$!$&)&'&*%)'*#+%+)"!&$%$#""&%!")&""''++'%"#%(&&%"!#)"#(+&!"&'($('*('"#'++'#'+!*(#'$$)$""'+&'&
@r3344
TCATATGGACAAGCTCATCTGCGGCCTTACGGCNTAATTCCGCATCAGT
+
*0:7E%;,9<'EE8!1!('2B5C)?*G,=BF$A/A<*!:6&7%%*:@16
@r3345
TTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACNACTCTGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAA
+
"*662)7B2==00?44(G?=-)A0:!@BC?&E'G@";.E%CH<?&@E%#+8#:>.;<?"(EF,%#><'D1@'8'"H!/.42?.1:&.%
@r3346
GGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAG
+
>01F6D!B57(@0&A9BB"G&8H."&GC0G.9(,GA."GCA"=3BE5=4F-?):EF0!7?657.25FEH/AH77#,<G56AF/73
@r3347
AGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTA
+
54?8.?4:F/#6(HDC/E<%926"BB)E77F!-,?/?H3C/40=#%8?8F=FDC8$#G((+:A"<A#H+<6,A&'8
@r3348
AGCTATTCAGGATNTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTT
+
%>9>+8,0E%=>7B76"6#3$*<B54C"@!3D@*A:CB,%F;@4*;%4980<=$:G1(3%"@*4//='%(6$8+,;D4(<#&)+D)?,GC9+>@
@r3349
GTTGGAGGTCAATGGGTTCAGGNTGCAGGTGAGTATCTGCGTATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAA
+
F&7@,.)F"/';;&#.HG3:714F)/GB>6/4:>*%'ACB&5?%*E*#'1<8D#".!@,8AF'A*9#3H;<4-1+"C((=&/#:7:==60A)%GB?D''!&6)($A1GG<4>3
@r3350
CCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCG
+
G5CH#=G*CE@&("$"?)*&*A8@.?>1D/*1&*6409H5<BA/'F)G>'"0?:%39B0<CCH82#F2%?(%+D&#)DH40@C>)650*CG(7/"G$1&57<!F)E#
@r3351
ATCGGGAAACGCCAAATGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCG
+
;.:!D%3#<44()F+60*11.G?.=8G,#0'AF-BG'7@$G4?%9A"E:9/D69$%9
@r3352
GTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCA
+
"##+!*"&#%+%$%+*+$"+('"&%#+%!!#**)+%$'$&"!(+$"*(%+*##!
@r3353
TCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCTTGCATCAGACGATCCAGCGCAGTGT
+
7;28);<A,B@-D:/@DH8.:4BH):&8HD:>B/0$2CC#:B0C.)A-D3>$%+$8.:+D8)8>G:*23C9&%C2FE55<A=6G,$1
@r3354
ANNACTAATGTATGGGAGTTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAANGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCNTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGNCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAA
+
"!"%(+#$%)+(&'#+*&*&)"'$&#$%(%')%(#$$$+"$+%"$+*#%#'"%"'*#)!&#*((+'%!#%#%"(+#+*##&!&(%')'&++"+(#$(&&'"+'!('$%+*%"$+)"$%!%&%#$&$%)*$"'&%%"+&*"$!+)*%)!"!!+$++)$+(#!%($(#"*+$+*("$'#))%%%%)")+*%)+$")!''%$"++*#!&$"&'%'+("!*+"+'))#!%%$&(+#"
@r3355
TTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAG
+
@9CA?2C<=(G!/A5*("G@D>4;0!4?<G6@,E0026-!=(A/?+5($D
@r3356
NNGGNNNNNCGNGNNAANNNCNNAGTNCATAGTNCTNCGCNNGGN
+
##$"#"##""$!!!!"$!###""$#$##$#$$"$#$#"##!"!!!
@r3357
CAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCT
+
209%9F6&D=485$1/$-6/&F:,*<%E<6,)5381;78>(%*H9-F*:6
@r3358
AGATGGTATTAGTGACCTGTAACAGAGCATTAGCGNAAGGTGATTTTTG
+
'0(:&(E0';G136.8:!9*((<B:'!"H31B/EC,588EE$"CC"$6?
@r3359
GGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGGATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGG
+
4/#0;D>%E,95E527--5"D8;2&%#-5.)841H4H3?9:B+:"AF")'>.8-##G9F0FG?@3:=?>D'@F;#/;,+2$%H'3&H+>:-
@r3360
CATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGATATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTTTGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGGGCAGTTTGTCTGCAAGACTCTATGCGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTNCGTTG
+
2BDC'F$@HC-H2$"?@5%)<23C&@*F<%E(78<4/3"%7A.FC49&FC.&2/H=@8$,$-!-,<.1'*3)"H,)(03?@&7=1AD"79>FG-8&*:6GH#"+(C-("<3'E02A5)?6$.4")+?--#G;5E5240%(D56>?-#1$"B4H=)!6"521A@95&-*41(?'AG0!1E:1),/=@+D>+E<403A,H8*'(6+E9(&1931E/7-!@D-=>%#46&8<>FGB6%01!0:F'=!8>.%=HC7?1+>5+/$D.90=)7A(F@>)6$&=F(B#G<4;409GA36:B#3-;".++.A(%5%)9)D0AC'G2(!=(,E*D5+/'$==!31."@4%<3C.6>=&A=>071&(.2):,8F.E$.
@r3361
ATGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGAGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATNATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGNAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCANGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTT
+
1''!+H0"DE5%"),92!CHH/16813C>?7,@32")7)#A<B!E#B,!C-#,F)&#C47C).129":)"9#!40>9+0:$&2A)<.'$!#3%,6F@%4-!)HG2>5&?219,D=#<46??&0&!-(,#DB=,(:G%636=G%1)1.;>4(BD8G:76A>5-8592>EA*<9>7G.=%)+G2$E&H?51D:$4E5+%-9E76:FF%E78%'*%8>-$2,1A,6@+-?4241EE!3/@4C7F87*!3+@>95$<"4B9>?A7.$A"8#&4A?=>E#DD->6@;9F2H
@r3362
CTAAATCATNACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGNCATAANGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGNTGTAGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTA
+
'$E6>7HD8'DG%#2;G@(5D<5A)7FB.2+"@*F+0(!!-E%4&D65)?=$&>.$'?E=:0D7A0F0-#93<*-H-?">73!&B'F25>1,6B*1/A+;3<'BB-6$49&(;3$/9$:%,7/1?1HBG8%*%+?#6HA=?/6//#9,6%G:C81#30E*=6B&%E6-;%0:4(4".*&/);-'=DD=9A',
@r3363
AATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGNCAGTACCGATGTAGCCGATAANCACGCTCGTTATATAAGCGAGATTGNTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGAT
+
0C7'2A@.9)2A(2)-43G3;0*81)H6:6/C1%=1<11&E*(>4CF25.!/-13F$7@&,B7@;!C0+">1)(<'A:#6@B21:C<5%!52;@.7!G<=(3-CA9'"C.11.-3C?H>8E.=G@E)4%$F/)C84!C?&B!?"%82/%.;%)DC5-+8AA49.D3/$!D!+)/!AF6BD4.-C8B!$.(4$A%!2%;*9$<<,F/9F>F.(-(:F.02A*B.A<G@!C<'60=/>!5$B<B&3FD:./G@>*,56#+B$4+D(F:52B4661"06"3-@.
@r3364
GCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTC
+
1+D/@>=$G>2,(>>C@,50608E+1)8-001$('G'1=@F'/6=5(#2
@r3365
GCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCG
+
9>H7-4?G@B+%-AG4?CDHBA;(%;%*8@C&E,#DGA&8BD=F5D5;#;3""F,5
@r3366
GCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTANAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGAT
+
8)HB43=5?4/"G$G.=#>B172&&D.'*3..<D")=.-64B)C'D8*:BH:8AG2H.('=9G+=/++,(A&'14G&0*H3!>"-(=8,<<'&%)B$$E,,H6C%H5!F>,5A/<H1<6#?=H+>*/H'!&#>5"AD@,40%0ED;240E>7G@A,@A'/(F<8479D;+7/E"+.(G:)5CFEH&4C2;396&-=-*/"1,4'FA63.00=H5G+7)+&216?-)9H1%-H$8,?;%))6,(.""7"$!6-5:?B$$B!(5<%2/5918)!9")H+E0*D8%%-3&2E%',.99;&6'?%
@r3367
CTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTT
+
78;F5CDE3<?;D(&.-:(<6G-;()2.(1H"&4%.300@EAA7?5).+=FE"")8-!6G9397=81'.=H0;HF%82A16.+(!C!"&A-G(/CG"D$675)5B-(DB7)$B
@r3368
TAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTATCGTAGGTAAATAAC
+
9<DF/%,(*$CFG2F5)3CB?6/D@)G.-9>7%#3:G!#")(*,&4@*1;/2A@7()B/33'>=>0*32C-9F!=B2CH0--@>).A
@r3369
AACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGANCATTGGG
+
1H7'@0CAH0A8=11=>21F%4-,</8FD."2E%(F*6"(H(4;D"7(
@r3370
NGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCG
+
"F4$:(B.D,<CA,+)8C#)0B:;+H@7=10)8!<>;A97>:<<*)F<0:9DBB>52B50>H)59C=@E/:@1'A>
@r3371
GCGGGTTCNAGCATCAGCGGNTCATTAAAGGCCATGCTGGCAATATGCGGGAGATT
+
&#:-+3/,!-GCH?:3$;137%@:6<B0+4$1<B*4%DB%FE'#<72&+>46"G'4
@r3372
CAACATCCTGCTNCTTTAATGCTGCGGTAAACACACACTTCCAGCTTT
+
H2(#"%9+GA!6.'5@B>@E/)BE"6&6G(/ABA2<$12BB3%))?46
@r3373
NTGTCTCTGGAAGCATTCANAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATAT
+
#022CE=26=G(*"'0+,23?0;288902EFH2H-6=-1=/2(.%CA6*4;F.2FF035
@r3374
GGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCAACGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGNTAATCATTACCGTNATAACGCCATTA
+
%5:?'(H#F"&:35BB6@*8BF(50;C6';'E12H7#-CE-4H<8=/2HA@)52$63,>#:'8?+,=$57A-08(%8+?82*7373*E@9F<+'8684&.7?4,B(.H*E-E<'A9"D)%$
@r3375
CACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTNTCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCAGCATACTCATCAT
+
EF3&B!,1*54%*>3/:H$;#.:.@"B:(.6-:7-96;6D%*@5C/=B'6<<&@.4&9*=#73EA%+(B9AE5:E?7.3-;>F1,F!%!8%FGC$'B=;G%4B):B2#)@;A-+-EF48<E;))C341@G:FH>39EEA(!+-;$#(7F*/E
@r3376
AACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATAGCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAG
+
0"=G539B#23?2<0F:%#2H&930?5!%8@-!&+7:9("57-HF9&'2,#E%4H25(>9D3F772<DH//27<%)F'G!,(7-,=3HAH>A3G1>"+H/-'0869HH8F+F'6+/5;.1%?<F',D*59%;CGG8-+$9<=C15F8FC<#FA?/):"/B;5"B:,)6+>$1*E:58")*4!>-27%GHC5<)$'D9$/0:A<5#'B"4-':.@#
@r3377
GGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATT
+
)4H$#-@5.36+EHG!!#)?8;4+9=!EDDE;1G;7-H$&*H3<D!*81)/1?DBD+
@r3378
AGATGATGGANAAGTACAATGAAAAAACTACNTCTTCCAGCGAGAACTTATAGCGAAATGCTTA
+
'*%(*"!)%"())"*&"&++(&+('#"("!&)**+#*!!)("++)"""$!""!)'%+&%#*'+!
@r3379
CGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACATCGCTGAACGNGATTATTTCACCCTCAGAGA
+
:'*<@=C,!+E,)8@E*,<FA$*F3<9G4*#*.(%B0?+EA5$-A%?F>6/C85#-:?%?10@#B?7/*
@r3380
NCAGAATGCNGCCATACCGAATCCGGCTTGTGANTGCGCCATCCCCATAGCAGCCATCACAT
+
+#A'?9/D@$,GH<@(9'(7;0$6-#*!7/0024HFGE%9#9D(")53EC$F743=$,<7&#
@r3381
AAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGA
+
'*)*+)#!*)'&'!"%"*+*+)#$%!&##'!*!%("(%''!**'('!$##*"$)+"!$!&
@r3382
TGNCATCCGNNGCNCTNGNGNTGGNCNAAGNCNNGNCGGNNATGNANNCNGTANGCNANCGGNGAACNNNCTCTNNNNNNNNTANNNGATTAATTTANNGTNACGNNAAGNANNCTNCNTNANGAGGCNCCNACACTNTTCNNGGTTATCCNANNNNTNNNCNCTCGTNTTACGCGGNTNGNGGCTNTCNN
+
$$#!#!$!$!!"$$$!"#"#$!$!!$!!!"$#"!$$$$"#"$$$!""!$!#"#$!#!!!##$!#""#$""####!!$#$!"#$"!##$#"$##"$$#!"!#$$$#"#"!$""$"$!"!!!"#"!"##"!"$#$"$$""#"#"$"$"#$$#!!!!!!!$!!!#"#!$""""!!#!$!$"$$$!$$!$"#""$
@r3383
TTACNGAATGCCTTGNACTGCTCAAAGTNCATGCCATCAAACTGCTGGTTTTCATTGATGATGCNGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCA
+
#''(%'!'$")!#''!&++!&(&*%)$')()#()%&#**!"#%#%#+*%*'$'*$)!"+$&&'!!'%%)!#%+))'"#%(&$*+&&)$+()%)*#(+(!)#*%$&)+$+%"!+*
@r3384
GATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGNCACGGGTAAAGTTGGGCAA
+
E$4&*2=7,'<3?!,%%.'7,2-+702.65,%-##1%E91B11(+'/<.HG?/$10$03<6.4AC?0-8D%<A-G<)&0;E+D5B3/#;.;*-&11E=<)(#(1"B?((*!;-)#;';<F$<7*
@r3385
CAGACNTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGNTTTACGCGAAATGAAGTGGTCTGATATCG
+
?90<)&$AB5/A>7(@=<0"='@D)41A)2@65.8F17%'%B"@$@C9<@*G:HG$(%+@@6D-:?42'81A+>)/G
@r3386
TAATNTTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTNTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCT
+
D.>-A2?5'*'@9,6C;4=/$<+'<.36$79+D66,,7C-D04+"C-/8+BD!/)32.2F,?5;?H($@(6B.:=3(G+5!<A'(?E&6;8?0;D"9@)C$$?1D<9#6<(C.(E?(H1F+)=;(F4D
@r3387
AACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCA
+
72%45C2@*4,EB))G97D;D<'9:1@%)&A317(9E0$H>-;@H)H6=D!1H!9),11)%C>#GH"@@
@r3388
TGNNATATTGGGTTTAATCATCTATNTGTTTTGTACAGAGAGGGCGAGTATCGTTTCCACCGTACNCGTGATAAAAATT
+
&*&&+"+%'$$"")''#'''*&(&"&(%!%+('*("%%')#%#'#")##'"''$+(*+)#!(!*&"+!$'&#+'&''*!
@r3389
NNNTAGGNNNCTANGTAATGNNGTATTNANGACNCTTTNANTTTCAATGACANCTACTNGATTTGGCCATACTACTAAATTCTGAATAACNTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAGATAACATTTCAGGGAGTTGACTGAATTNTTTANCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCNGATATCGCA
+
%(%$**("!"*')#%*)(%&%"#(")$"!"%)*&%(&*"%%$')(%(%*!""%)'%("#+'(*'!*!&&##'#&%)&(+$**"+$!""(#%)"')")(($*"!#!(!#*"'!%'*&)((+!++&%+#&)(("!$!#"%)"#"%#)#!%)$%&'&)!!$)'+#$*!(&+)!'%$+*$"!(#)+'#$*#"+"$!#('*++)&+"&#%!&&*(('!&'%&+)**#(!'##'$*"$)%*&(!)$%++&%&#%!&!&(!+%"&'!*+#%'")+*%
@r3390
GCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTNTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCA
+
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
@r3391
CAGCTCTGAGCCTCAAGACGATCNTGAATGTAATNAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGANAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCNGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATACAAGTGGCGA
+
A&;$6@&4$+--4B58'(/<;""E<1>60=D;5!EB/%6!77(+%:<.?+5B6E?D4#88(G49*)DF$14E6?H>@:F,E'<6-''=7C7'%BD=C.0!/C)<:".$D%!?@8@AGA<73D1/;(C/:2CEH<9(13GE2,,D7A(1;/7=/CG063,@E%@(7=,G=@G8BAF3)(;06$</(1$!'(D0;H?F)1$8*)*)B;7A'=:,A(C>-D@&$1
@r3392
GCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCC
+
@+).5(>H;=<-B>=G$?$>=.*3?GD=%<);&D0C0-C%>%9.8.BG)/2=#H8,#3'13!-=9=!GG5*9GF&@<GD=:<.:F
@r3393
TNGGAGCTAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATANAAACCAT
+
(!:AC'C'+?)B(A@'3&D*#/."H#5/:%;A3()1-D"3.=-D-*A/@9C9C/6DA*AF*6,572@>'.5106;$AE1)<F+)6+4"41H.HC''""0+H,*@4@;EE,%
@r3394
NCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGCTCAGTTATTTACCTACGACAGGACACATCCTCTTGAGCCNACAACNTTAGTA
+
'('+;C)$*2.8:7E45=A5%)D>(H/>4&6@4$").2'0<694-?0.>.!5+C%*:1C4=B292<#FE54&E08@<0@$@1!C*:+!-#-
@r3395
GGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGNAGCCAGACGGAACGANA
+
(EFAAD>$?!8@:"A,#4.AA$@F=:;7)<*-=%4'!BG=,&/&H,)7"<$<)"?
@r3396
TTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAANCCGGCATGTACAGG
+
>/*'=BD.B-87/@&D/F>B'&H!@9"'97&-D)3,2&3EE5,C291F.#*0>2?<G)H<&#-G"(F/*A@#;2(5<3H=7A)25+BC+(>+%H:#4;0H0A!,$67.
@r3397
CATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCC
+
=*3-?89$9+C*CBA<%)2.??%=3D30&=9+F<",F.CF=@>0%@.!$E7$BF!8?3.?+A98%4&G<:!;;(/A7-8*#F$&2*-115;$?D$!8A8/*3*?:&G+D&BF=93!$D:6?<=5@C&H-&%HG975&CEB(,67'
@r3398
ACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTT
+
GA+%:D8/?/8%4;4,8+*.&/,07@0$BB;@DB10&:%<%HC'<4456%D5:+$?<<F2+
@r3399
ATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATNAATTACAGCGCCATCAGGCAGAGCCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCC
+
1)*$HA!/>1"#1"(#&@D'57-%)G01G0G(%4-*<9;80%@!,&!.!+49<%+&2-?2!CB!>=#<$,&&#6'$$2D?34@1E+>=$+DG927).27C<*A2+>2;.%)/7=(=/!&(@0A7!5!D4!-!6D-
@r3400
CGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGA
+
='#F-)#.&+2?G0<@#<E'B&AGE7;:4C"H)2D7-1EG
@r3401
CTCCATTTTGATAGGTTGCATGCTAGATGCTGATANATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAG
+
=(8+%4@>!5E@E&;&4A;<0@>.<@:E%F8+3DH5'#+,;"2*;"5@*$9*#/%7-8;@15#:1H&2C1D8&+=&495F+93$(<D6-=6B46(5</1+"$1@=66'+=4*5):A&HH:DE@*5=H06E!<?CCB%638D?<@",>759%.B!9A,>E$8<8CH95-@48".!B9(99<DDH7F4E@:4?C->'#6E(;7>:H&7D&,E,+;)B4?4@&4*""!#A:9*0-=!%;3
@r3402
GATCGTCTGCGCGGGCATTGNCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCC
+
HEG.$/GH;1C&*(+BC299'0FA<C5)E4F*/:E++,3'4F<=1,)<,7%#4>-F":1)".1#G,541;(3GB9#A;&(?8,)4;G>"26
@r3403
AGCACGCGNCGCCAGCACGNCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCT
+
<"33','$+801'E1C&,G93:")G4G5&;FD&)=?.F2;(>(HC*8+:*D191#G+:2
@r3404
ACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGA
+
G/+$3<4C78:2!E7/F+(B?(!'*:AE@,08)049B&8?'B
@r3405
AGAGAGTCAGAAGCCGCGGCCCGTGGTGAGTCTCTCATCATCGGGCTTTTTGGCGAATGAAANTTAGCTACGCTTTCGAGTCTCA
+
0;97&)F>3!/6(9=;6CEE/&.**9;*%<8>:*&FFCC9%!4FB;F.9=:G/-E-@,$@08<6G?/4('/"#+&!1F94%0!9!
@r3406
CCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGA
+
G.&-D)6"232%><3,?<7A=89&2@1:(C6+&=41D95186GDCE?#,9-2G/*9/F/GC#5/FH%$<E8<=)7&/GFE+1-
@r3407
GGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTGTGCTTTTAAGCCCAGATAACTGGNCT
+
+CH.98'3?<:47-*/H)(>@!G'#=3!HE>4<<D;F'65!=1@64/B*8=+3452=E$F+<&?-?0'H1<<;+10*8&%-*FC@)#?17H?;%!A7''*0#4@-!G8=:4"%
@r3408
TATAAGCATTTAATGCATTGATGCCATTNAATAAAGCACCAACGCCTGACTGCCCCATCCCCNTCTTGTCTGCGACAGATTCCTNGGATAAGCCAAGTTCATTTTTCTTT
+
0.75('E-.%:5;A1AE@GC;&('&>A4F84:BG);:7,:/.@E,6$)-H@@E&:''$8+>,1*H"&:&8%8E$D50A%E%7G,3+B=B65?,!(.C?E;*@D'CHE3'?
@r3409
NATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTNTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGAC
+
+%!)#+$'#%$$#'"'(&%$!$))"$*)+$'%&(#&)%%&#%%'*%!%'&&"!!!#)#$+#$*(*+$&#!%'$(#+&"''#)+'&&#+!$*#&!##('''(%*&$'%"++%!*()%('&(#"*$#$*&%+&+'%%""*($"+"%&#')**)"!+)#)*+")'&&(($*)'%*(*)!&#$*"##$&#!!+(*!***)$#*%+&+$&#+
@r3410
CTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGNAAG
+
(BG5E8<C1?9"*CA"43B/,D@/##".2)8/)A3:?)26>H(#B-
@r3411
TCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCNGAAG
+
<;&<859A@7E,(=5-E5&)>.).("CA/"+,:8%:--/B)A&#(:2G9D@79/CD;7G'CB"2*;$GC"!HB!7=>5*1&7?74H6,H
@r3412
CTCATCTGCTTCTNCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGA
+
A0!7)6,>:*)F&1<5)2!:5ECG096-(4!*;,HF/!<(3.@0=@B5CD8
@r3413
ANNCANCCANNCGAGTTNGNNNCNCGGGAGTANNCCCNACNCNNNNNAGTNTNTANGANCCNANNNNNTCNAGNANCCNGNNTCN
+
"!$$!#$$$$#$$$"!#""$"#$!##"#$!$!""$$!!##"$#"$!$$"$"$##!!$"$!!"$$#$!#!$#$!"""$!"$#"$$!
@r3414
CGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGNTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCN
+
4':BF*B$FG1C.%A;/D0B,2)'F0C25(5<GE8(12);CD0B737)FG#.0;%C54-!<**!>8?''D>E>0F*=$6;0@/1FB,C,4'+93G78$,;;>E:#'>F7A.FE=*4:!-A:1D()2,'D0@2(21GG>(%C"#'<+$0::(6(H;9-B,'C*":6><"2
@r3415
TGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGNATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGANGGCTGTTTTTACAAAATCCGGTAGTAACTTG
+
1=%@,5<.G7#=;?>A#@8$D+8EF2A/&.1!E6$H9(BF(C#2:4H)1)C($!6',7/#0B+GD'+61*5E>+?30&)%*G9E76&<"%4@-,A+/#!3#?*F5)&08.$1@7!A:-5.-24006#=*=?8;4(F662$/CC-#=+':3%DE*)91G+/(+=!<6E=G=2,'
@r3416
CCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATNCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGNAATAACACCATGAAAAAAATGCTACTCGCTACTGCG
+
6!.C*-6=$HA9;2%%&08E00A2;)-7&F>=-D:E7#@3#9*'H>"5*G+<9*+(#>+$!A.G*%C=1;'E:=<F.<$.@-HD,461*(%H6*$3"-)*.A8&3H%?D3347:0'/!!/(96EHHB8@15$E5+38&1'#-3*68-F:6+>1;$!E.634'587+D;C2+""A#+*)9.,F=<B4-D;)9""),)2*?4F.802<-;5>A
@r3417
TAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCA
+
C%<+>+(H1H$4(;C:?F9>6F0:=&;EDD7>>%B>-BE;C+7;4,5B+*00-C'G@/;((9C:D*FE2<A#>&>(1:H4#/-E"<(H<1/GG2G1C776"2<"+F):6.BC(#%HF,6=1,%D@*8G21!!B):74*E1*C;).172%"B2?1BA.#B@#GBH!$+G?";F4CE$?.9-*.,&)9
@r3418
ATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTT
+
64$G113;?*+A9)!8,F$1,'5/4A42C#H&;;@4*B.6#4+E)$E=1A.?B'%%188E;2'(-E54D/4?37
@r3419
TAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTANGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTC
+
&)92D=E9,"'BB:=91?E!>6$60/1,G2!*(BB1H0,&'6G-4!%F7(A+%<A4B6(E0?$'==(=5:07#)>HHA+6C>E$D,)AC)0"/9*7;%*/$))3'6<%4<!G7A'4)9$("&":!-D/#+)4$-%!"7-(>7!)3")=/:,@C5(&5:D**&,%-5:+6:(B1<G%H)@,B*==H+A(CH,
@r3420
NAAGGGTGGTCATCGGGCANGGTAACNNNACGGATACCTGACGGCCAATCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTT
+
!*$(*!&!)#'%##&)!"""()'$)#%##&#%$&((&%+)*'())+&%#&+''%(+$$*("("$+('"$(+'%("+%%$(!')**()%%(&&$"&"$(&%&""&!%#!$'&+#%$%
@r3421
NCCCGGACCATTACGTCNGCAAACATCGACCNTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGG
+
!#!*"&+'"*$$'!+*&)'*$))$"#%*(%'+$'''#""$!")'$+$+'#+'))%**%+#***#%"&""+%("#$#)$&+)!
@r3422
GCGGAATCGGTAGTAAGCGNNGCCTCTTTTCATCTCACNACCACAACGAGCGNATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGCAATCATG
+
DG<0?/-D:!=:+2A.(7+>#E%57=6461=//*@1)3B48@AGD4.,68*1CDE5:7,>.98<DA4!3G?F$E.*6@0;27$%4,,<1EH2<><%H50A+)5;'2>=B&#?!+)#@337*1E@GB->'36826/:#!
@r3423
GCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGNGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGCCGGCGGA
+
D<#4$&E71-')DH&?,!;>@*&C3<)?@2*5>%.97!@:!#"A?D-6#>E4><)4'+"8=,+34E'$8(9A9C+9%9/,->E6A>G(<@-@>%!84,9!7$4#@61>#G'#2):<0?)&'//&)'!"4D9C8*3(+E@#):=:1-
@r3424
GACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTG
+
=F?0-.$#G:=B!1-EG>H-''@5+#F-GH:'1C-/30B(GDBA(5!.<?0C74F6(0%9F(5<H;HH">,;-5@7)@CDG;*$(%G0<%E5$,AG'#75H9=1:#B)$F3G>!E?$>;$3-$G!D/B:7/7"+7*.0&'64H#AD1AD,2B;9(?@?>E8"?<04?4'.#<804>%.C5GF
@r3425
CACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTNGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTT
+
&?+=+H8.64:"=>4')C/)H9HF,1<':F>?=#/">6H&./C/-G@D60-7"A!G@<-%9D*(&CG%(:5,,)#",$;1@.5+(H+.D!*!C=4.HG:'*GC"<;#?/<!B7H.(+"B4C@8DE<:!@"11G+-)E<C52#&"GA08C))D'?)9!D%,'EC;F';C:%2E'455='C#GCG'(!$+5G5;,DH%
@r3426
CCNGNNNCGCTNCTAACAGNTTTTNANNNTCGTNCGAGCGACNNAANGANNTNGNNCNGNNAANCCNNGNNTNNCGGNACNNATCGATNNGCTGTNNNNCTNGNNNCNNNANTCTGCNGNTNNNGATGTGAANANTGNAGANNNGTTNGNNNAGNNNNNNCNNNTTTNNTTATTNNGANNNCTCANANNNCGCTTNNNGANNNNNCGANGNCTTNAGAANNGANNTTNNNNTNNCTCNNNNNNNT
+
####!$!#$#"$!#$##$$!#"!!!#"$"!####$$$#$!$#"$$"$$$####$#""""!"!#!###"$$#!$"#$"!##$"!$"!#!!"#!"#$##""""!!!"###!!"#!###!"#!"!$"$"#!!"#!!!$##"#$"$!!$!"###$!$$$""$""!"$"$!##"#""!#!$"#$!!#"#"#$#!"!!"$$$"#"#$#!$$"$""#!$$"!""!"!#"$$!#$!""!#"#$$!!##$!!!$
@r3427
GTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCG
+
17"G,4@3<#BD$/%:A,6A6&CF<!?4/*=)EDE,0GH-6.":D+8F%D&&7;DH'312.%='
@r3428
GAACCAGCAGGCGTACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAA
+
9:BG8%$FB4*D2!3$0;DH!112G.FG7"9C)>4A)"'8ED244H<H-5816)%:"==FECA<&'F7841=':=/'$(
@r3429
GGCGGTTATGTCGGTACACCGGGCAGCATGGCNGNCAGCCGGTCGC
+
<39.95&/)!;9AA/4=2C5%D0G==F8&#E',57+8/8$-);75&
@r3430
TAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCG
+
'EB?4=+/D9DE<-*G8<-8'-7+/AH&ACH-)1H%+;</>"
@r3431
NAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGGCTCGAGTGAAGCGTTATTGGTATGCGGTAAAA
+
#23B22B,HE-=$&91(C()60H@'F/*<A>2B,CD@?24+-7<33EC8'GB.:*CE:?'!%2B-H73)EA,23(&$*A13@+D>><1H;5'.<+/!=&&*;G57.H'01GD3(-B#F
@r3432
CCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACNGGTCTTGTTCG
+
,,+<3$"E:('-*0E#14A-77,='@&1@<:)%+/DA=84F.?6*+%-=/-
@r3433
CAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGNGAAAACGTCAGA
+
2*G"D%)C49?AD>?*7/.1$"AC/A,09A!@,#@?A>09@9F0G-/"&:<:46)
@r3434
CACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGANTCAATCGCAGANAACNTTTTGAATGCGGTCACACGTTAGCAACATGATTGCCACGGATGGCATATTAACGGNATGATNTTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGAAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATACCGCCTAGTTGGTCAC
+
+*%+(($+"+'%!*'('"%!%"+!*("%'%*+)*())'%+('#*+$)""()++&'$(*)*((#*')#%""!#'++*""*(%%')"**(#*"%*$("(+'!"+"&#$*'%''&'"%!"!'"%)*+)'#')+&$&!!*$#&$++''$(%!#*!!*('"#)%")+%(("####"$"'"+'#((+!%$#$+##(*"%!%'()*'"!%)'+#$(%*(%$"%)#%*"&')()%((%"$(#+)%)%$''*$
@r3435
GAGCTAAGTNCGGACTGAAAGGNGCAAGTGTATGACGGGCAAAGAGGCAATT
+
!-(50*>#2;3C!1E;/.7F2"G$9?')8B>1B726*.?.C=;6.?6#F5:)
@r3436
GCCTCCCGTTATTGCATTCTGGCTAGGCCNCACTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCA
+
A9(C1C<CE-!97%/;'B"H,$C+22+EBG+C$8@4<8B:)8057F/6"?"EG4$,1(F-F/CED(=7+#E*!AA"<+?::>,"*FC,A*2,0C<4F6ED-/57@
@r3437
GTTGTGCTTCTCNANNGNNNNACNGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAANCACCTTGCGCTAA
+
"*)%&!**&)%'#!!&$!'&!&(!+$&#)%)(#!"$$!++"$%#*(!$%%)++!(")+%'+(%&+%''+(+&#%(
@r3438
AGTTCCCAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTAGTTGCGTTTNTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCAT
+
91:..'"$'3!F?A)D)A?%.)#$"/#','%4;H-4&4G9-"!=0.<$4>8D=>+'?#E=CH<<E!F*@!6?;?B$5((9516438+5$)@7=,C)A=319,BDG">-F#2(##255"2);H?*.9#.?$5
@r3439
AGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCNCAG
+
59*8EC5@0D'6*E,"4+*;,+1B(0",D!+9'%!&1HC;$%>"@E?;9:G*2!/
@r3440
ACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCAGGACCANCGACTGTGAGCCACTCCTGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCC
+
(')%+$%'"#!''*&')'#+')+!#+*)+"&#+"%&+'!($++&!'!$&"&*$(!$#"($)(&'')%'$*"**"(%)")%&+%*+")"+)$'%&&*)##%")"+!++"#&&(&'%"&+&!%*$)("$#**$$(*)'+'*(''"+$"'#&%))((*&)"(#'"$$%#)$!%'
@r3441
TTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATCTCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGT
+
H$H"8E<;+.(%7++C<5,3?3,*B*+G)7<3@E4$&&.%D!./"/<5@()1B&44&-0<'D1D<F$F"!G.B"-"*9$(A<C9;=%=7/'"<($B7?0&$=)<>!7,.5E':4+-"@=#.'+C6'?!=%;B;:
@r3442
CCATGACGTAATGACAGAGGAAAAACTTCACCAGATCAATAATTTCTGGTCAGA
+
0)/6>E9,4713H<%E&G%E,73"B-D)-<0+>(C"!?1.GEG1(&/9H(5'?A
@r3443
AGNNNTAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTT
+
)*"(%+&&"'(&&%))$'*$('**)"('!&!$!#%!*((&**+%($#"'+****$+%*%(!!$%*+(%$*%"&#"
@r3444
NTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACNTGCTGTAC
+
$2>#D,;)B*2+=A2E,D?-":%0+3E12/?A)96+B!/*-&$;$A1.33=>=
@r3445
TCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGC
+
/#B558).34">AB+&D"?#5,D3,C3%%'-@=*1()2>4A?-G+!961/C'2!-*"5"+G
@r3446
CGTAACAGCACCACGGTGGTGGTGAACGCGGTGGNCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGGCGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGNGGTGGCGCGTAACGCGTCCGTGGTGGC
+
,-"2<)=,5F9@2-52#+97#(!-+"#803>G=2C>D/=,)D!4%@<FAFH%>:0%?F*DHA2-B7/B2CH0<1,>#.-D:9!'$"&23%GC:1$=F/8?F!(C=+3#:@<@+;??:@$1@'D>B*4F,%"$"*:-0C8F3B!05F7*+#8./+!A,F47!(6?1(G/-@0H7,@<2)BAAF*7:H;7/@=(546=9@8B!;C)G;9@@E'/D4E*?H,':#1;,9AF8BA+&-/>9319997"6*5(C1)=:.6>)F?:%"#2*;+B@B,6$!)"$6%A=
@r3447
GAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGAT
+
1C/D51'H$C-:@9$6@+$9H#83AB<<6/<?;/-+EDG/;:7"(-G,-4-)?%H+E+@.?%A518
@r3448
CCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGCTAATGTGCANTAGGAAGAAAATGATCTANATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGNCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTT
+
:6"!C9A+40?H19!!<)-AGB>=G;2/H@H"-)=G=83!&,71B(;2B/EA<275/@6*'54@;>DD#<!4H3?"HBBF.!G+!G?&1,"'/?$*#8/8&/6@=H>/,D6*%'8:8;+A=8H:H=(1AGB#>9C($%;G'1C/CD;.B@BH<G<@>B0":7&3)6*>*9$$AH00)@/=,9)G*:B-6:-(1%66"B*H29*.HAA&1#!)9FFF4%:;>."0
@r3449
CNTGCTGTTCTTGAATGGGGGGTNGTTGACGACGACATGGCTCGATTGGCGCGACA
+
"!5#&G+7';?';'F,7./%BC;9>4=80/;18<.+8!43?D#E9.9@1=#E-HFB
@r3450
CAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATNTCAG
+
D$0"3G*&&:=*8.12'9%A(D!'+H;"8.A94;-+=(@;17'F">6>0(7A/1.72,#50E40+8(9
@r3451
TAGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCNGGAGAGGATGAATG
+
$%)@C"60:.+550:;$663E66C3;A*:8BA-0B!+108,)'9=<B)?*842H)G,;/HA'E!&3!*=9
@r3452
GCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCC
+
1#6%;!/';,;*A,573@C(%++-5.<.D)#-C"6##"&(A-2#!<*!;
@r3453
AGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACNCTCAATGGTGGCGGCA
+
=,;/*<=75H;A!?-51&*32!,B2$;F7%&$1!4!<.E9*-FH)H4-:<E76B2+<BHA+$5B2!"2=&4/6:6'.*H+8#-4<07
@r3454
CCAAGCTCAACAAAACTAAAGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATC
+
FE;(B1/B%$E,>F/8?+5#1%$.#1>:#D8DEGD3DED@5H!3E%,'>2C'B29E:3D%35D1FC
@r3455
ATTGTCATTTAGCATGTTACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCAT
+
G!>2D(6"5.<>1=7A>7%16E608E0$%;:E2)<%42B$/3$$C<>.+57)63#-<:&/,)H2A'&00/$D0H&/?.E58G#65>,,@+55(&<+-%H*D,3"&:7'5A:A(+>9C3+?(6=/8%?),G"7)/*-26<G5><3H,*#>(:&C?43F!"&H;D-(#,+D1:=*"D$.5,9+=00'1%/;.-C6H8(*>+
@r3456
GNCANTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGCCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCCTGCCAACGACATGNACTGCAGNGCAGGTCAGTTGCTTGCCAGTGCNGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTNATTTACAGCGGCAGCCATAAGGTGTATGGCAACCCCNACANCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCG
+
*")&"++#))$%)+!''!)&"!%"*+&%!)!'#(###')&$&)&)*!($*%$'!+("%+$&%!*(&&%+$(+#*%'*&!"**)$)&""''%$"%+)'+#$$##$!#+$+'!)*"+&"$!+$)&&)'*(!$'&+'*$%"##&#+'$(*+)"*#"$&%+'!%%$+*"%$$**#$*$!%("))!'&(')#+#)#"#$#"'&(+('&#&"!''(($)%'$#$*)"$#(+%!)"&('+'(*"$%%*)#)'&(&")&$#)(#)&$#")&%("&'(+''!#%$*()))"$!(""+)""*$&%*#*'&$($$&))((($%'%+")($*&)"(*'+(+#!"!%##*%)*&$"&*(&)"$#+&!+
@r3457
TTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACNGGTATTGGCGGTATATGGA
+
6<;G><24*>%H4./A6D/-A./+-/@G=.30&5!9%-6#%)(&H39+9=H29
@r3458
ACATACTNTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAANCTNGTCTTCAGCC
+
C'?2B+B<37%@3)C)0C:$%51<B%99'<5%D)@4E:49#>#6$.CG3:>)#'+"F2C=<4!+9?G4=<HF5$B/<F?.'2!3&F
@r3459
NTCNCGNNNTCCNNCTGNNCANACNNTAGNCGTNANCNTCCNTNNNNNNGNNNNGTGTTNTGNTGCNTTNNTNNNAANNNNCNNNTNACNTCN
+
!!!!!#$#"##""!$#$$#$""$#!"$""!!#$#$$"#"!$$$"!"$##"#"#!#!$$""$$!"#"##$"$!!"!"!$$""$$"$"!!#!##!
@r3460
CGGATTCTTTCGGGAGATAGTAATNAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCC
+
4(8'",&H3)3G-&"$&.$2">G#$4*>&53-'H.GD$D;GH(7BE.7(C/3#=4HB0.=B/@
@r3461
ATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTAGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGA
+
'?/9F3$759H#(<D#0>1#;2.&:?)H8.&-<BA2$(9/GGBF(H>9;$#%<4:D/484E'/0-=B0+98:?5,7DD@F/F??G?
@r3462
AGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAANTTGAGAACG
+
@(0!7-9*0!)(#/%;&?<@++6B<A2-'525H8G.->H:$H#;?E8$:@>A/"=H=2A:(3%7A29*,/;D?B+"1503!CG?5>F"G>%%)9%)70?1==F4A<:108<
@r3463
TTGATCGCCAGATAGTNGTGCTTCCGCTGACGTTTCGCGGAAATAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGAT
+
FA=9+E"5)@75H2/0;G3;A"E:%F;5+0+=048+").+3">(4<G>F'(7$;1*('66.E34>G%1-655>5B<570261/*D$H3;B(G!8?<&>F;+4C2)!*3;,H@=;/
@r3464
GTCAAAAAGAACTTCCTGCCAGACAACACGGTGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTTACAAATATACAATCCAATGGGTGACGATGCGNTTTCGCCAATATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATATGCAAATTGTCATTTAGCATNATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAG
+
;A8%&&,A.(BG4=10&A6@)4>=36,(H#G>63>3EH8:B*B(D4&&%":E89730"4&DE@%%@;50*?-D@)HFE2!B>&FH$#,6:;@,=+'9%6@;!;",866%%*G-$#"'!9=H;@)H,?4*H8'1%@CG!F45@&5+B1!C?-1.1(9@C!#7'>*"/CF+$:(E;0B1B/7B1DHF<05/7:-=.$*H<$>!F":D)-132H54(17@5A4<*H3)A4F7<6.1;2457.8''C"&87.?H/@-C-34?8'?B-%C2)G0>?A)!>"54>DF+32(/)1.1*-@%B&9./9+C>21*=
@r3465
TCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAG
+
5%"0B3"0)-(9)*+"<:$"B0=&C+1;32!0?1?&<"GC>G0
@r3466
CCGCTCAGGCATTTGCTGCNTTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACC
+
'=ACBB<G*(98*81HC.$-!=-&8614*3)GE:/E,9/?1<&?:47&@=;76"B6+9.-'0@28%1H(-73775B3
@r3467
CGNCAAGANNCAGGNNGNNTGAACGCCGGGNTANATTNTNTACNNGNNCAGCNATNCNNTTNGNCNNTNGTNNNGCAATANNTNCGTGNTANAG
+
$#!$#!$$##$"#$$"$"!"$!##"$$$$!"#!!$$$!!!$"$$"#""!#"##""!#$"""$"##"!!!##""!""$####$#"$"$!"#!$"!
@r3468
ACCANCNANANNNATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCNTCCTGTTTTGGTCTGAGCTGCGGNTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTT
+
#$#)$&!'#""#"+&*#$'!&"(+$&&$)'"&+((+'))$))"'!'(&&$%#$&)!+$%'"%&$)((#+&(*&"#!)+$&'&'!#&%"+$)("!*"'$+%"$!!+)'$!&)#!*)!#!))$!(("$(*$)&$+!)+"+*!#%&%+*'$$%
@r3469
ATCAAAAAACGTCGCCGCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCNGTCGATGCTGNAGCGCATAGCCCANCTCTTTCGGAAGAC
+
)#&+C2?'299.?&+>,.BD@'C?#D*,-CB0%.F"6!HGD-8;CBHG#/;D>=+?@/EA!0A.57*@//%=,",E?2>61A@:5:/:=,E08!'#.EDFD%2).!*,5);<4&-#H=#C48;<"B'@H,+6.
@r3470
ACCNNATCANNCNGNTTGCTGANCTNTGGCAGTCCGGCGGTAACGGATGCTTCTTCCNGGCACCATGCAACAAACTGCCCGGGTGANGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGGGGTGANCCCGTTTTCCCGAAAAGCCNGAACCCACTGGCGACGGAT
+
&)(%()%'"'")#&&)!)$#"")$(!%++'*%#&))$)+()&"()(')"("!#$*'(*&!&*)!)$)**"$""*!#*'*%"#$$+")!*')*!*')'&")!)$&&))!%#'$&+$)*(%("+%#*')#!'(!*+#+&*!(')&#))*+!*!#%(&*(**)&!$)$(*'&*#%!#("*(!#&+(!%*+&!!*$+*
@r3471
TCACTAAATTGTTTTATGAAAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTT
+
%G?7<83>;$G:>G*8+9&6:=5(C!D&%>38?F":3*5?:D=)DC&H%B<0<6?0!-3';9$+*A&F-D
@r3472
GGACGATGATGCGGGCTTGTGGAGNTCANCCGATCTGACTTATGTCATTACCTATGAAAT
+
#+#!'+"%*(%''+%)$&()')('(+*(+#'&'#*'##"%*$$("%("%"'!#&'**$$+
@r3473
GGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGNTGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGGTC
+
<(FG2565%=E(8/29:0-/94-F'>>-.(7$@&))86*-"529%5%,B42/H;<"AEF(=C+">)>E;6@'A((2>2"87)++A2A1<=(EBBF.6&;E!H.@(-2@)B@&%?&B?@38"H=@?-&5%36.-$$6+.98@6-*#=<!>.<.C!H,FH&B'3:GC/4<-!7=2+/2A=%2B"5=;)%'70F6.#193*.9(#(#-&*"92()*%4.0G">>EA)3:EH-G,#3@.,?$EC#5+1(:*D1?G#$-'8&9:)
@r3474
GNAGNNACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGTACTTGCCGCTGCNCGTGNGGCACTGCATGACCTGATGACAGGGTAAACGGGNGGCAACAGTACAGAAAGACGGACNAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATAT
+
(&(%!!'%%*)$+*')!(&&(($!%!((+!)+(%*&&$!(+#'%%&+!&)!##"'+#!'+$$!!%'%#*"+!'+"+*"&&"$)'"*+*$%&*&*+&*$(%###!!&%&)(%(#()$%%(&"+"$#"""%!#+&!$**+'!&""''+')'&)($($(**'&'#")*)%"($!"%(*&($"&!!%)
@r3475
CAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCANTAAAAATGCGCCGC
+
;.HA?,HC1&+B#(%G*$+'!(#DB%?<G>#='1#+G8*86F!:;&4;G&2&&3H1%<)F:FD+.?#8,
@r3476
GACAGCCAGCTAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGNGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGT
+
2"!9*'>?819F=E,+9;CGB(8+<>=5+0+=#"%+-:A)/>$?D$/*&,@5=$2!-.-.';!H>H$E4>E(=#3D))&>.:;55?B911!2&',0.BC0+2"%2%)BB-&"&D.F*.#231@DF+-8<-*5=A=!57:
@r3477
GCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTT
+
++$+"!&!&*!#!*!()#'!"$)(!'#*(%*#%)%")!%$+(!*%&!"(('&!)!$$&*)%&+"+"'"+)')!%!'&)+&(%)%*(+!*'*#*$$
@r3478
TGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAG
+
CB$<D)2C+#%9;G(&72$E0D%6-C$6@B,,01>,3%'84%:/18='6A)0$#"@+
@r3479
AAGCCAAAGCCTGGAATCAGANATCTTGCTGAACTGTCAGACTCTGAGAAGGAAGATATCCTCGCATGGTG
+
*&@1'6:1(+@557>;4?"649858#<)6G$2><%2+6B=C2+!85#<<@0%C7&&%"1"AD*#G!=3".1
@r3480
TTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCC
+
42A"7</;#<28%>*,)&29;ABB>4*$:6GGG=BG22.>">84G"#>FG>,;<4"+C507:>0#"!?<.'0.0*2G3B;!C85.,E!5:7$"<&*=
@r3481
GAGNANACCTACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAA
+
%"'&)'%'*#(%(*%+(%*"(%+#)'+**(#!"&!+)$&#$*!)!#&'$+(&%+'(&&(%"#!&!++"&++#&%+
@r3482
CTGCAGGGCTGACAGTTCAGAAAGCGTGANGCTCACACCGTTATGTTCAAATGATTCGGNTTTCAGGAACATCGCTGCCTCTCCGGATTA
+
(E;742A'E0F60>3AF0B<1)G66>D))<2.*'G::B5"7H=((D36&-%E>HF.+(?BA/%9FA4;DB$:353#8$0)*-47;?6,8F
@r3483
TAGCTTCTGTGCGCCGGACGTTGCCGNGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCA
+
0())G%H;G3:EA6&?:@%*&AA+)!G?FC97H!AB$414;$A3(7=B?A#9G:C;4:75*3"2==44-FFBD5>97:$
@r3484
CCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTNTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTNTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGC
+
=:9/0/>=!%;&)A>H6!=A-@1&75.=!>C):.*=;.*9?!?+1>(F!C)C(CC?E3-?1%4+89GE("2+FF7F/0HH1:G421*2&GB:"(6,.D74'6333+F)*?.F;&F$=BA*<87A>6E$5".ED<-A?'%19>3;"8.<?-;&,4.:+/%CH/'8D+3!A@DG1<0>98&9$-4C*0/5%-:-82*%<6)7?<E&7''!$2/!B
@r3485
CGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAA
+
3,GD&5"G&F%C,15$1H*8<21+/3E:1;:>5@G?-C2880H:!E#%'1'4@1F@17>E/=FG$0;2<;=-=13&!0>-?$2%"6%+*/:,2",2DA3:070"B#>=776/-:<6E2)$-
@r3486
TNNCCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGG
+
)#+)(!$("%'(#)(%+)!++#)'(%"''"$$(+'(#"&#)#&##+++'+
@r3487
NTATCGGACGTTGGCTGGTCATATTCATCCGCGACNGCCGGACCGCTATAACCGCAGTCGCCACCGCGATAGGTCCAGGTGCAGGTGTT
+
&*+"$**%)!(%$&%(&$(!%+')&(!+)!!!)+)+$#!*(+'*"*'%%!'**"#'+*'()'!+&)$$)$!##)!#("$%'&(''$!"$
@r3488
CTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGNGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCNATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGNTTTTTCGAGCGTTCATACAC
+
EAC;9&<F$H0;*.%&-3=)/>DD2)12A#2)(&%*3?C)A29,(##AB:6E+15-*224;E$0?<B'C*'/B=5G5.F,:+7?+!$%7'17FCD!;'(+F?)9;:@A78"A@B'';:3&59D@.86&CF*17%*E%/GE4CG?2)'!%682=:F-)9B5%,?4G#C("$5?:-?$;H%1163&,A!+6#F5A=%0:9<D@$2-)C5=G,CDF8(,E,!<D#5A385#:.B9BG&<7E&@$$:57<#H$G&-D)0>CD&
@r3489
GAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGNCTGAAACGCTTGCTGCA
+
:'43/<,>%5"%&%5G=D)*D@:EHB7;$GH/B%0!6?"F@B@.0"1D>1-0E<A&$?7&/?(?'%2:390G,+4><"
@r3490
CNGCNNCGTTNGAGCATTATTCAGCGCCCGTTCCTGACCTTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGA
+
%"$#'#!#"&#"+$'''*!+!+(*"#*&%+*&&&%%''&"$)+'+$'#*($#$"!"(+&"$(+!*!&#*""+$+$%'#'%"$$"#""%+#!+#"*"("'!&$*#&"(+'#!&*!$++#&+')$'#!"+*"%$*"*'"$&"%&$"+*!")#&&+(!!)%$%&&"!&'(%&&)+)'*+')'&#$%"#"#$!$')**)#)$$''"#*$$)(%(#(*!#*$!+%%&#$)%$&"(*&!&%'+*"%
@r3491
CCTTCAGGCGCTGTTCCATGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCC
+
+"+(%#!+!%+(%'+)+*+&%%*'"#+#+%$!!")#(%!#'%&!$"()#*$%#!
@r3492
GNNTNAANNGCGNATNNNANNTAGCTGNGCGTNCGNGTTNCAGNCNCCNTCTCCCTGAACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGNTNGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGA
+
&"&&)$$"*#$(!)&!""*!)*&*'()#(&!&$%("$%$!()$%'$*("')*+%%%#)*&)+*""!"&&!)(#&''(&%$+'#"++(%%%#())+%(!$&"%$%)*#)'($%+&%%"''($%(%+*')(*%*()(*#('&%')((!*'"*'(!#"&'((+"$"(*("++%$(#&%$*%#&$""&"#')
@r3493
NAAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGACATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACGTCAGCCACCNTTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGNGTTTTTGATGACNCTGAAAATATCAGCTATGNCGGACAGGGCGTGCGCGTTAAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATG
+
!$+$"'&(%%(!#('*!+(')#!+#*'!!#'&"*$%''(+&$!!+$($$&)*)'+"#'**"&*&$#'#'!*")#$($#"!%")"%%*!+&"%()&""!'*'*'#$*!#+!)!'()!#))#"!&(&*$**!!(+&!!%'*'#((')))'"#%&)!*+(*$$***%!$'!!$%&!"(%$"+)+*&)'$"$%(%((+#%&"'*()!+$)(#)!+""(*"%#&)")$&"&!%%$('!#
@r3494
GATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCCAGAAGGTCACGAATGAAC
+
7(8*B7"+"$>!$=:2B;()";03,8;$&6C*#GCB@4H(CD*2C$:+B*11"01++2B*2!?@;B'%<:
@r3495
AGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGGTGGGTGAACAACTGAACCGTGATGTCAGCCTGACG
+
H/84"6@@E$*'@E"?-!A-)G+"(:$:AC..E$=5B),827:F"#<<$$:/40H$%?@3&+>/C;0;=F.?:-!%4,$8
@r3496
ATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAA
+
B:="B<84!E407G@21,@:-769/$(8<?(C)1.#G!C&/"3;0%?E:>+=9D#011-3E2F)",=1"6C;$7><@+!"*2-=D7>,D5*<&99GA:9C0#:54G4(,+56?.2.!;:C=915BB:(56C0BB#$=9&7@?=@/D./C6,.%7@,C?-B<;F=$C))%AH(,2H4
@r3497
TGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTC
+
-3+(.<%G(H0B5;G&*@16C*H#4D:-0&&<$BHD5H''@!3:*=/"G5("").!*?=;9$2/621CD>.C97%BD'46>B/:C1AH!HG/;F$FG.+1%!(0$:DG04@&3!'E.*$2#4424:!/#96">+<#%27-:<7GG:B>!0))H..
@r3498
GTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGA
+
=EB<A7;<2=-9/$5F%6?9,D5*43B'5@2-?#H<14;*9,
@r3499
CGAGATAGCTGTCGTCATAGGACTCAACGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTG
+
*&**#&)+!"''&)$"!*+((+(+&'$$$$)(!&'')#))!#+'(%*+($%+'*&%*("$(!'
@r3500
TCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATT
+
2'2;H1H6F$E"!>)+H1)9B=@:2C6H)C,#?@%3&/0<*C54A"*A@("5>6-12%0?E#+E
@r3501
GANNACTGATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAGTGTTAGAAATAATTTCATTA
+
&'*$'*)('#%+()(+&($$)"&)%*'&+(*(+++*(!%#+'!(%$"+'$%&#''+'!)$$%&#!*$$&'+&#+
@r3502
NTGTTGGCCCATGATACGTNCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTG
+
*>#%=<'*<'"+,4737+"FH!*+H*?-<C"B/F!(1$2C4B6%.A<"0HC4;D940)'8/F<2'<$$.-3+>3!,21).2?72&<*5B2@.5!
@r3503
NAATCCTCCGGCTCCGAGACGGTGCTGTGTACGGAAGTGAAATATGANACGGCG
+
)1:H>"35."A-!*:C*$6+;7E95:%#=2=.94D%4FC'0F%%<+B$H9(.6>
@r3504
GCTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGNATGTGTAA
+
!>2.'!5D@&4BA;26'@DH5=#'2,!6;H83D1034$%(-6@C"9B1*F%@<H!E5'D(H"9030/1;EA%;>=/9*/6?1-:$!.6@E@H?B>#,(;:70H(:5CD%.">4>6%*GG!)</B6)>"#D7D8081..?*;7DC%GD!%(FC@-%%H%5:.@6;<)A'"=%,?!8!/@6F:4DH0,&)G#!E*G/2)+72<-'8:=@&/'!0@?;A87
@r3505
GCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCCACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTG
+
/@.3C594ED!%76*-30:5(&%/8G)G$D1(@:>?>0;500G5*?2G6B*(F.D++B?5#+@7(D=99,*8(/9<A@58>5DCE4C+B"2G=(4=GDH2ED<D1=D"H*<<#$)'0(D!(11*H81C1C@.HF;=%@(16'--11>#D&381?.;)@&+:95/8+8&<;5"481H:9F&5*9E;>;/;039*525<7>;"<9,9%,;/"+E')9=D'G
@r3506
TCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGAC
+
5,H=&8?5$.*9%.9:4=5GC*#"?/1+:3.A:!%)"CE%4&0/A&;
@r3507
ACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAACGCATATATAGTATCGCCGAACGATTAGCTCTTCANGCTT
+
,&-*9&/7,%G3?E)9$/1:(83?.;HG>6+%-F!#&FF"HCDE*-)E$D2-<1'G??$A/&+)1&6F?%5.=21B=;F3;@-H$C;A%E76=-
@r3508
ANATCGACNCNNTCTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCTGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAG
+
%!#)%!*#$&!&&")(%++'"()%&*!(+($!+($')"$&"**$&+)(('+*++(%$&%+*#"(*"%(!"%')!'!#$")%)%+()%%(&""&'(*&%#%)'"'(#$#*+#%"!+#%&&&"!)%)*)$*$"")*$
@r3509
CNGAAAGAGTGCGGAAGATGCAAAGGNGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTNACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATNACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATNTTGAATGCGGTCA
+
&+!)%($&"&"#+"!&(+)*+#%)&+"#%"('")!(**(+#))'&*%#!#'($"+)&'&')%&*!&(*!(!$$"*$(%+#*$&%'+!($*#&((##*"""$("+#")#+$'&%'!+$'+"+#")!#$%"+'#"$*$'&&!#!)&*&#")"#!)!%%$+("'#'&+*)*!&%")"*'#(($*)*"*+)")"()*'##
@r3510
GAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGNCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGT
+
H9<$52%4'BB?;%A4>&0A"@HA0E1@,"74$*!."7G3AE<0$#3'-88.$4@#;6?BA1;07,&C8'#E5&8B="F$H13E0014"/8#=E5F<(6&+F!';+!;>:''?===*>);5AC7=9)'G8A+0@!G!=5(!0;$G)G.7C49G@@;08F1%G:
@r3511
AGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTTACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGAC
+
'/?1%5==/#65#8$#'!"6"CC/;356?)@A9.+D%8-:1F=8CA7.37-,:<H<*;&4<;:'C2%?G<7?59*$DA%490'/->$0EH.$
@r3512
GCAGNAATCNGNNNTGCAATCATGGTTCCTGNATATGAAGACA
+
(&"*#&&)"#)"#"%''+!$$+&$$'"$+&"#&'&&$+%*+*)
@r3513
TGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGG
+
.(&?%4+=#@:%-#>3;@H!!.11)>#6HC)/"08B&3&D%*+$5"B83"$H8C?*1-EG?5
@r3514
TCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGT
+
.33!/AH0<(EG.,C.<7".D'4)16E8!!,%?F'!F.FB*;2;//B8A<?>-(@%!7,H8"2/F
@r3515
GCCTTCCTCCGTGTCCTCCATGCAGAGGCCAANACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATNGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCGGTCTGCTGGCGTTATCCTCCGT
+
.E:2.-*5"FGD70?A"%.91/>0&%H.*,4H?E(=B#%.G<C:%#-<$,+D&9)*AE3&..5&&=85(256$!H0H/</:>D&E-/+G#0=G.0H-0)B1=?'#;4<@4#G2C.#(-,6C$A(7E:$<(;=$75:;FD8".A)?G!&>?>;FHGFF$+
@r3516
GTATGTCATCGGCCAGTACTGCNACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTNAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTGCCGGTATGGAACG
+
&+!)')*)!"('&(!'#)%#+&+*!'$&!#)"$+&#++"$+(&$*%$)"%"+#("#!+()!%!)!+)*'"+!)$&!"*''&+($*#%"$)!!!#&+&&#$+*$"+$!)&+)#%))($%'#*"*&!+%)'%&$*#"%&"+*!($'*'$$%'&*#*'*
@r3517
TAAACGGCAAGATGCGGCGTGGCGNTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACC
+
0<A%*69407G'!(+"'<:5H##$&GH8.A87:5#"HB;GE-C$<54H*=%6/$1$AH#(F,)!')DDHH<=;6.48#1#03,'DFG@36#BC$D5
@r3518
ATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAA
+
B5-#@68GD-EC=>B?5<HB6B?G)<E&CB$7<G%4+$(=>
@r3519
ATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAN
+
H<!?'@H$=2FEGHF8B@.-F2($2@EC5-@@00)H<-,=85+1DFA9(-C*0)@;D>E
@r3520
GGAACAGCGCCTGAAGGAACAGTATGGCNATAATCCGCTGGCGCTGAATAACGTCATGT
+
(H1)0F6&F&<8BF17?77@D*%,F-;?"/A(,@8+FDG6D@D*@3CB9;>(-.-+5:#
@r3521
CTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCAT
+
)E("D826AEH<%$087E2FE*#,C:1;D0$<':%!@/,5?DG<-?;<<2<?CB&@5>!;!6AD&A#%/;(+(;;:$#?B<F9;-9,"@?6;5"-*G";.(%#B@.&77=/;*4=0)F#(2&
@r3522
AAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCNGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTAT
+
4'9)80&B4C;6;-4;,*0GHD*,&=6A9/%'@2*#47/6;6=9F.D328.4G<!<DG*B.<>AFA$6E1CD64$7(?@0/@C:2C<;:*4%:$(2%!9E?*(F-+<>:
@r3523
TCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTT
+
3D@/A"HA%G?,."!9=+(-F7D55'9(";<)/29H':"0>7-&-C$'
@r3524
ATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATGTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGNTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATNTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGC
+
?E:D+",.92"";&*+?<D+G?'6%'-$H+&&#?0.=GFG=,197</$(6(B?.D;C>334)(6GC;CFE1474%/33)+(*8/A!0A#2;&"-",E*+FC)@';&*#"2(!)G3:>(=6GA)*93+EB$#=B/DE*(:#>HB/:F<?+.02GD*!/A0>=3,5>CBG>*%H?52E%4H(D949,9+#)>B4H".5+B&.?)?D8:/8BEB)7**+D4E-4.2'.E6).%09H8C'+
@r3525
AACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTG
+
,%29>7HF<-.7G.<E.(!294?8>=63")8<0E.H</436%;?C/B&D*3.
@r3526
GAAAACAGGATGCCGGTCATACCACCGGCCCCAATNGCTGCCCCCCATGCTN
+
7(A>0'>12F/34+):+5B*#+39%;#>?D=F)/=<"A.;0:C:)6<006<4
@r3527
CCCGCAAGGGTGCTCGTGATGAAATTCAGACACAGATGCGTGATGGT
+
5E++;8!80F:&5>*@3=9H.3!!0)1*3@@-E+8>G?3@$0*@>A?
@r3528
NGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCNGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGG
+
&B%4607*'!AEC&3BB5H,=F10>B(2AB9(E=@F68CE/FC40:#6'G'(8D>%3,<-04*0)2?/&?/C-F!$1#6:;?-0H"#0BG=!)G'8+#1BC:%?33>;7423A
@r3529
CCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTC
+
=;=-38.%7E28,4CA%4.+&F++%,E>2(93%#%$<#$./@:;0D1;;C81D(=D%$)8.H!C0908(,9C.):7=*3'%:8D<)2)6
@r3530
TTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGC
+
GB?#A1:8/C%5'=20C*1G$$(825/1"2#8$7*7-)GA2,%&D'6+=4"-
@r3531
TGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAA
+
F;B6"E==51<*"1B>8/2E+"1#:!%093G2$6;=*@08-?A@,C>23AG20:A';)F;44&%</=CD%-73="";"0:2:-@!%2%:,?'4;1+%3;"*/@?F*#6',+=0$&C$0FG<%+7<:$:"F#6(/17$=E"E:=>)=$:B@&+A7+0E(6'&
@r3532
GCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGC
+
%A69&-;:%:#"(BB7*-*G"20A49/;*?H2@&4-FB!D0&672*?DFE0.&D-
@r3533
GCNTTGGCGGCATAGCCGTTATTGCGTACNAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCCTCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGC
+
($"+())'#(&!%+!()&*"("'%()+$+$+%&'*'&!"*#((+))$+*!*#%!#)(&%**$""%')'(#$)"&!%*+&'!$*%!$&%%+#'(%&%*+#(&($!)+$("$(!("#'+!+(+*')"%*#*!#('!&++!"!(*$(!!+"(+#*)*(!$*!!&%$)&$(#*()"#(+((*
@r3534
TGGACACTGAGNGGAATACCAACATATCCGGNGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTNCGCCGGAGGGAT
+
AH'B4A63GE4=:$&B.*#++G2-16950D/*0.'4#+089H1D56)F()'(,7.-%5;,=9D94#>$1#&FFB:8C/!0-23>
@r3535
CACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACANCGTCCTGACTTTT
+
;<-C<.+1#FHF31E>0")9&@%8/D(%:+/28;%-+#'22-C$>"*'941-=<>%FEH#&G$&&=54"G
@r3536
CGCTGACGTTCGTACAGGACCGACCNTCGGATCAGACGTGGANCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCTTCAGCGCCCTNAAGNACCGCCATAATGCCGTTGAG
+
+!&+)+!+%'+"+%"%'$!)$+&"%($'#&""!)%&$"$*!'%&%*"+'!'+&%%$)!!!"$'"#)*"#*!#!(#%#"#$'!(#&$#&+*!&*"+%"#!$!')*()(%$!'!)'*&+*)+*+*')!!$))(&&*
@r3537
AATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGNGATGAACCCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATT
+
+*'("&*(&(()')!"$##&+(++!#!$$#$((%'**("#$*#%!)!$'&)*%)#')#$('#&()%)$"*+("*""")'!!%'""+%)&+%%##+'+##$++
@r3538
ACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCC
+
9*#(A&3!7(1C$G%F"?*A5)>EB+#B5"(6H/AC<8<(H@)E):!4:$/#88/F;>GG@:@+G.%14H9G.C95>1'B>:*<@;C)?95G4%79%&=B
@r3539
ATNNTAGATTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCANCAGAGTGCTGCCNGAGCCTNCATAAGCAANATCAACAACGACGGACGCTGCCGGATTAAACTGTATACCT
+
&&##!&(#(#*%+#)!"'%+'%+"&+!%(((+$$%*))'(&"%&)*&&$%')**)('#%*$+(%+$"&%*(&)$(&&+++(#+#+")(#&#%(*$%)$*(&*#$%'+++(+%)*+!%$(!(()(
@r3540
GGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGAT
+
->37;!/57F5)*?'68D$8*6B@@22H82.,6/$5.+58%749E?*>D>AD72198.2
@r3541
CCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGG
+
'<083:A#'B,=2G7+$7"5C%84)!*:9:8+='7,/G$#'?@'*4!7-G059!B<33<2@D08-6
@r3542
GCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCAGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAA
+
EDG@(BH?=G,F"?&4;&"(+10-:96!H6;F6"@,/EF!=@.,G*A)2="#;B;@+7C6@<"%.3?1@$F&$)7.=2"E1)3$'7#">553H&D5,7&+'4D!C1%$7,>+<72?252:/G2D.!B,C12B1>*'"<24*3#F+%;9,(%/7#<,3,=D+;6;=2AB1<D."
@r3543
AAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGC
+
$/B54(*%*?86#(F=.ED%&C#A#F$3)"0/G.$!6);7.!-#4*45@;FC1B"'/@.!;H@6"C55B.5>;8!E1@B*)<%!">;H3E&*834:*.#A(2%2&
@r3544
ATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGT
+
,!'','=>5G<A51C%$/(-+-3C6'>7711BG%!F$D4G%.*17
@r3545
AATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATNAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTNGGCGATCTGCACGGATGCTA
+
"8HD*+(G:9$9"?>)&8=@*B:3G#;C%:4E%&8@&.@@5#F;972,#F+$(C),'-&=<:@/,F!C7/;F;<?F-60(&@?-*-&"*H3;!69HA:D(A@#3+:"4(EAAE-<%79,D-()5'?,,.A;$&%F>@>7<E3*><H9C2:8G!89&:;:%F"HH:>$3F,,4>'(@F4B
@r3546
CGAGATAACACNTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTNTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCT
+
-196HF>$H5D@/"#-*(+2D*>/.HH("4B&:C-):C=/HA9-4#//&D;&3.%%0-A1&C26B2G)G%6CG1"G==:@-00?,F==!!7$5/H<%#1':%%..')2;)>A8#0B$4D!E.0!+$E5/=/4$9E9%1="*#B>/87'=,82#+@$3!'<64'*A#*C%%)1)/;<,:4@G7*';!2C)4;8E,7)?-@
@r3547
CGGGGTTGGAGGTCAATGGGTTCCGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAANATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAA
+
.G$0$5!).39DA3:"!B08H@4,6(//0AG)+9@"*=GA5H7FDAHA$.A*/?7%+:H+H*<9?B79+9*3GD'C2#,4$!/<"9,&#");421@%*FB.B-=)#2,1)4,.@;45G25%)1H?07"5B)@C789<EH&H6-DA$G:2'$3$4<A,;8#G-3BGFED%1@D13&A:;%E7,#?#7>8'*F5%>G6<2.HA74,#)7;"8F?2E/+7,8+:+=!C=)3F1)'&E3;D#$8%:2E59:D)'&;+<!0G("F":./>F->"0,?%<;4
@r3548
NTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTTAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGACACAACAATCNGCCGCCACGTCTGCCTCCAACGCGGCCNCGAAAGCGTCAGAGGC
+
$+""-?BH5&&5622%/21)%1$=*7,D7'7G12'B'12>$:0>E-#D<>,=$$+CA-D*@3-.G>=E%7:,194H1H(G49%DBE327*?%3*'5E"<F$8@,8C56<C89@D6&,002$BD4!C:>50"6<>A$.:6,4?5-*:%<?F/9"%G0F28*$4?4"7(GDA4%*H@E?".D,-(=H7348
@r3549
CTGCCAGCACCTCGGTGGTGNAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGTATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCNTTGCTGCAGGCAAGGTCAACATTCCGGTAGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAA
+
H-:'05'/"$;F29,<)D&'/)@E8*'/(#4)*,:6:$!-'%(&?#72CH4).?7/33*$8<+D7A;+:F6;.C(,/&$7F.G8E==7-G7*'6B$#0!:<>+3?5>5B.6$=()07A'47+%-*?-&92(5!(%F;EC*32)</F,G$-'&#A)@:>GF3D(%C+#7'E+H2"22/4ADD3"1(37?@1D>E,!)-*5B2+,'0B/;5/='&'.?2(
@r3550
TGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGTATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAG
+
B*6C>D,0%>9(/+;?8H1$4.3;5&64&5;+&63F?)-$#7,.D>*HC9CD--&@3-!3*8*5B;B&:B4C44(3!#A01(?=!%/(+3H(63--1./7/1C0*HG!%:*8%99>F32D!(<.D3H2?,2<.48'EH:EA0G:%DC6/).".8!A#4?AC!:1G>D8H!?6D1<G."7$(<>)8"!EA-4<'.2+6:4G>=++-*E-8AH38@/FD9)"+D*3>(!1ACA3E..57E#!&/.*.H5>.A08
@r3551
ATACCGGGTTACACTTTCCANCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACC
+
F=(1G?;6?BG(D&,!71CH.,";4,G"@;./C448C(-@*8.&+;HFG/3-4FE9<#!+F
@r3552
NGGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTNTATGT
+
!/C:E*F+!!D?0.8!H5A.5,7FH@.*D9)?)=4-F0"D,=
@r3553
AAACTATTACAACCNCTACANTTTGATGAGTNTAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGTAC
+
&+'$'$+%)'##!%('$%'("+(##*"$#!%$'&#)$((*'*"&)"*+$'*#&#(#%%###+'%((#++("%"$##(+)+
@r3554
GTAATATCCATTGTTTCTTATATAAAGGTTAGNGGGTAAATCCCGGCNCTCNTGACT
+
)#)%+&&)"%(+#+*)($(+$&"$#%#+%#*)!$$$$#%+(+(&$(($$&$(*!"%#
@r3555
GATAGCTGAAAACTGTACGACAAACGGTACGCTGAGGGCGGAAA
+
&D@20'D<=;3!.+?G1@GE!8>)%"<A7#2/801&")@B;A7$
@r3556
CATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAANAA
+
%()(=9%:"!4"D+":A9*:E.1=)G),E$=)=*-E88H":&HD1D)&+48@1$5=#"=/=&0"!,&E!D=1B*C28BE/#C6!,-7/05:!(D-!D)-.=>8AH>%>3:;
@r3557
TAATTTCATTACTCACTNCCCCACTTTNTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGCCAGGTCAG
+
'%E&6,F,7BF65*&F>9.A/B8EDH0<.&/=BB?**++)A91*$;-B$$4?D'>>:/C2:$&0=GD/>:@E8
@r3558
NGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCNGA
+
"0D)>>!*!=-#"A05-)B1DF/+23?848%$49@F,;76A=7>#,&>)*7*A(%)+,4;$H"B45=2+&3,+D3?!%0(5/E<
@r3559
NAANTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAG
+
%)$"'+$+'"((+&""*(+$'$'"'(%%'#$($$##!"$+%&)#)!"#+$%'%&$$!%#&&+(%
@r3560
AAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTC
+
'(879>9:C86@8H(<?G1HH1B)=8..5>010/GHB#6"7(G
@r3561
TCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCNCCCT
+
B9+??8#*6&F)@"0141:3(<H8A&!:":,3*8<=%5D/=9-B+E#%'>-<12>"1."2(';,'8>B:B1(<$@'96D1@B4GD&B48B&#C/'526+<C,80EG56"=&-"30:;F%,3)95#F$.-6.B4*F-87%:<1@0):D-@/=,9.+%:G2!0GHD@>(/!$%,"894*+
@r3562
GCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTACTTTCAGTTCTTCAATT
+
7!C')!8G=?>=:6B)?>-?>0-@7-#>C!9(@:A??::F4<F<H/182,@$EA4404:8E
@r3563
TATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTT
+
+C&?*;"7H?/.%9*"(F>GE/1.+#C?=</1F(%5>/9B((!GB-E>:6!'+G6602AFD;;3G0!'D*'E
@r3564
GCTAACGATATCCGCCTGATGCGTGAACGAGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCA
+
8@&3B)=9'/>:;5F<'4@2'A/5F!1-5347H&;H4(="(FB0)9G#;H608-3(9!/B/!B#/3<*9@D3@=60*/*:
@r3565
NTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGC
+
$8(3:D$?'0),G42.,.1;4B>A?C7F62/=E1@3G/3GAC<<"@+<70*&-*4204$F.C;=,4C!#>=5,H"B@)'+G/4:>9B'E/;2
@r3566
ACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAAT
+
BD&06!F1;=5G-&#B7!CH7/C?)952C##!7H?'+5+=<#=A6G$,7!)<);-C?,6%$=3;0B#;.<52@$59&G#3(+":&)&+43HH;5EA-=&G=:.,6(BA6H32)"F5BAH+?;E1?.EG0FD;%:(0%+=>+.GA3>*=%$9-8-;5*
@r3567
GGTNGCTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCNCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATNGCTGGCAGCCTGTTGCAGACGGGCGATAATGC
+
$(%$&$"%+%##&((%*+()#&+&$'+#(*$%&!*)'"&*)$*(&(&$!&)$!))"(%&$&($$+&!)(&#((&!&)'&"%*!#&&**$*%**+$()(&*)*#'('+'&%#!!"+!$'$*+$($**"))"#('*(+%'"'*(''+$"'(!'&!*"+()"('
@r3568
CGATGTTTGAGTACGGTCATCATCTGACACCACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGAT
+
8!95E:#04?+;-&)G$($)!158F4#"D7'/$,!=?&G53>+*F6A,G%5>BB'9/9A?@$##65C'E)'<$34>,+E/7876-0B>>8G+G,,94"=4.>3=D*$B0E#0GB/=+&5D)'=,-"/,)G&D<H8,=15>E,9*7+,;!G93>
@r3569
AACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACAAGGGACT
+
>,?.!8)0,(#!E.#7.FHE(?!C5DBBEB+D3F$?1:5*A7,-;3GH<$=."4.,A+:6""!*$'D0B
@r3570
AATATCACAAAACGATTACTCCATAACAGGGACAGCAGGC
+
*+49E,2HF-"%BCB<'>)*/C5*G&$)$E-05*<F'94*
@r3571
ACCACTTCAACGGAGTCTCTGNCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCNTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGGTTTTCGTTCTCAATTT
+
-6@H;*3+'*+"0<6$6(77>*:"61F:>-78,G>FE#,#B7B--F9;<$%/DE28;F:?36:'?A@(7.B+!=:;*'/<12CD,9#CG"=:,=5.GB'!&'D?')A!!(/BFD6F42.G2.H9>B2&5#88=36<EG8"F5<;920=64%H"5D>A!&<
@r3572
NNCACCGGCCGNCGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAG
+
$%#"%%+%()$$#!%*')%!**&%')%*$#'&'#"&%+('++)'&#'(*%#$%'('$)%!
@r3573
CTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATCGGCAGCGACTACATCCGTGA
+
2)#36B-1>")*C2+A,(=/21,G6)5?F=4+5$4D?B0&B9-H<@4/G+(,21:@/&<&+*"0G+<(.8*9A=5E9#?H/AC8?.0<5)E"D866-12+<<0C*1
@r3574
ATTCAACGNGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTAT
+
D4,,AE*-?;#94/$%85::-;A'33*.:$&=&!90@C2F04AG5#2;>B,&85HC:90GCA*)&12
@r3575
GTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCTTCTGCGCCACACCA
+
D#%2>562"-<5%+.=<2*#:,A:3,>/3=A/8HA4)H#7':2(&(?7A.@)G;C)>B*9@("D'9(:!9A(AA3
@r3576
NANGTNGNNTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAA
+
###("$$&&(+*"*&%*&$&")(%$)%!'"'***#($%#)$)"$&#)"($#$#("+!&
@r3577
CTCAGCAGTGCAACCAACAGNACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAG
+
D>0*B#AD-,%DB2:(F""-3*H,.@&;#B@F)+9*@?HE;A6)#=BH>&D23:@2'"9G5@32@?G4F70AE'9*"/?8$@2DB@'1
@r3578
TCNNGTNTNTCGCNATCNNNNTNNGGTTTCTGNTAAGAATC
+
(&%#%('$!''"%#'%#!(#!*%!)$%+$)*!)("!"#+##
@r3579
ANTACCGGCGCGTTNCTGGTGGCGATGTCCCTGTCGCANAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTNCCACCTGGCCCACGGAGGCAATTNCTCATGCTGAAAACGTGGTNTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGNCCCTGAACAGACAGAGGACGTCGGGCCCGCCGAGCNTGTTTCTGCGGGAAAGTGTTCGACAGTGAGCTNAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGNGCCATGCTTGCCGNGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATG
+
%&#)$+!*'#$%*&+'*)+$)(($*"')%("&&(&$%)'"+%%*#!%$*"(#&&#'&*(+&$%')#!%$($#!&'##%(%*$"&*"''+#&++($'"&$&)!(*$$#*$''"'#!"(+#)($"#"#!)""((**$++((+%%*#%&)#'"*&!(+&*)#!(#(&##&*!%'%"(#$!)"()#!$&'#!$+&%"%(%()$)&*!&!%)&+!*'&&#$!&"$((*)%&''*$"&&"++#)*%($$)&$!"((")$)%#)%%(+&)*#&"$)(#&'$#*+))%$!(*)%%&'$)"&#!*(!'(*##)&#&'#$!#"$$)(&(&#%&+""'%"*$")#+!#%+&&$)#"'!#(!)(&($$)('!$")%#)$$%%%')+%!$$&'))'&%'%
@r3580
CATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGG
+
$9G5G;>.3C%->D#F0*3H1@"B.F4-#6D>5-1"3C9?'F
@r3581
CAGTCAGGCTGACGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGC
+
@G@B1?;D$B36:B@C&>BEG%*F)&0C)>0<:-74-@$6%%@$'"H47CA8:"(F/-7<;.2<@*7C35/H!1$<B9.2#!32$8,.&80703128C
@r3582
NNCCATGCAACATGAATNACAGTGGGTTATCCAAAAAGAAGCAGAAA
+
$**'+*%*)&"**+'"$!(+"&++$&%"'#*)%++('%'#(*&***$
@r3583
TTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATNCCATTTTGCAACCGNAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCATCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGNAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCC
+
CD@D#6B+6"9!FG."%BH11E?1B(,051=2D!,B;#3$$A+.CDD#G"14.-7HG8#F>,;&7>CE'7%&7@C&-#D$4H&BB.3()H5*AECC$*+BA%D(/>//:(03E;9:B,3&$<#0:47=6':?H#@)()@9B!<DH0/&*%97E+#923H<+D49>#9&=!+2><>-:F/7AC=C>>>5:1(+E++&E?<H?<?D590;24)?&0$BF)!4H2@)-,,F(":@4G'=<H!/#A=-8685&1C-A?5$C,"!HCBD)E#=6&A4
@r3584
ATCATGGTTCCTGCATATGATGACAATGTCGCCNCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCAATG
+
(H='13$*"?78<C'H'A#C-@&9&<5+/F45H!'#98H(A&.79B,E3!463-A.4*F74-+AFCF70B4$7+0
@r3585
ACCAGTTCAGACGTATCCAGANTCACGGTATCCGGCTGCGCTGATCCCACCTCAT
+
<"/G'.9)9CH(G8")7$<9(<@3!>+F+<>=+,!:@3081A?G<3GC9"3H=*2
@r3586
CTTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGACAGCGACATGG
+
(!#+"$("*!'$*'&)+"+%"*%+'%*&"#!$'!!'&!&$&"**()$+#'$%!!*!*"#!""
@r3587
TAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATANCGTTCTCCACCGNCCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCA
+
0:F%$):2=$'D>'0/&E63,AC*+"6?$=$D>H2%&6#-*D=C:"/HF!CD*&!:,2+2&.?CH(B"/?=($4FA.DHH.2;-87100!=1.E(!G()G*0/'<>ECD1><3?2AG"%"?*F66<B
@r3588
NNCAGGCGCCCTGCAGNNAGTGNNTCGCCCAGCTCNGACCCTCAAGACG
+
$*)#)))(!$))#*!"$("'&)#%+$(+))+#""&"&&%+!"%+*'''%
@r3589
GGTGGAATAAACCAATGGACAGNATCACCGATTCTNAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGNATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAACGAGGGA
+
5:G7'@2!4>FD239?9>AC=9()360")'7!(!B136F!');>023>C%536@E>HA0(:>?/%31,':$+<>=7%"7<70B3#:5#+&063%D$CC:!G<B!?/)D+$<D5%:B.6*:,DG++;"A<>!1G5G4H)@E,!B5?61G"0!$/7)81/553<BF92><G=@$6;E=?-&E"
@r3590
CTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACNGTGAGCCATCATGACGCCGATGGAGGCTGTCCG
+
:'G7:<(*/'">4%B$AB#;7?+$7#6,;@,B)(3:*-$HF+;$)61;H1?9'6/&3<4&9/#;8+4@9@'52GH#3D<"%++3G@AD(B5'(,28A&::&1FA*,!.3)'?G-65C%>9/(E5#$G<!'2@G!F6/<*50B8-GHA-8C5;?E,"<&:,9H0:FC0$.<<7HGB3">'/4'6;-!H%'16%8B4;"?9'AC"&/;$,>#5)1G#><9;123'5@;="F5CAE03H-(B77"-66(7)$*B)=8"%(B%:'7GD
@r3591
AGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGT
+
*>;4CD.G/>(99%6H1&C$68*9D8846"-+-@43H+<F?H2:10HH9C>-7*>6-A-++GH/FB$H4%,5D4(63<$4$E6A+=CB*73.D<%
@r3592
GACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATAT
+
,H<B78H86?@')77'?DG:,=$&.&6"1$2E#%E=E++90BE6B!/?'<="D!4A.C+:$3
@r3593
CGGGNTAACNTCTGAAGAGGAGCCGCCACGGTAACGGATAACCTCACCGGAAACAANCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAA
+
$'*%!&(*%!%(*&*"$!+#"($&'("!+*"*'''&'*$""*&)#%##&!%$""&###%+%&'&+&&+(()*)')%&'!&&+*")!#*)!%)'#+
@r3594
ACGTCGGAGAGCCTTCCNGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCC
+
&H+(47BF6)C:951(<5!@19,'@3'2+(25A!5?$@(7$1/&3-@##270D)>6,($H9DH+"<D+3?&*.?H02=(=C6A$!,48"+,';?6
@r3595
CCGACTCAATAAANACGGCTCTGTATTAAATGCAGTATTA
+
4"!.,EH.!FHG>0#D)'6$*DF,';'#/.8"%EB)&$@*
@r3596
NCAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACANTGCGCTAGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGNCCAGACGGGCACACTGAATCATGGCTTTATGACGTAA
+
"3:9/H#D-74HF1.9,(F6H*#'B(5!5.$%F2+#$CH@5E6*8H?+-E:1-5H5=,%G06=:A")B<::E38H9>==2>1(C<E6":,1:A-)')*E//:AC"H25B=48(1H?;FD2+H9@110/*#6=#&;D91,(<*>(G?#G76956#A0%"H'+8*G6B(.5(EE+>HD7901,<!;H<4E5,#*"G)6A@61G8,.:D4(!&36/&'&6(%5/$%G=0+4%+@<)/GE$.%$.)6A/B>EF2E!<80<3-4=9?,E"'6-/%>B9E+8-7C7=/;DFF>6?9-)&)3<<.*'!D0#5?A%AH+@D*AA"FA44@4,'-1+E?$;FEDB0E3<F!D;F'-2(<DG=0C;2D<*;$.4#>4"3FA-C?=F<%";C+
@r3597
NATCCAGTTTGTTCATCATGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGNCGA
+
"*:+HHA=+-2;F&D.&5E>0B?%B6B:G&#)?<-G4HBG1$.H>(81;;,.!=',B&."?,7@@$8<;025$GA6>$--)F%6ACG@.7!0*H9F"&30+E!!B(%:,'*.*-6-B.<E,6>>?B.0"A27F#A33%F7@6.;0
@r3598
CATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCAT
+
G(;,4;31CG*C3!D%.',C#)A<=A+@H:/.?@/B7H52,5;C25-B;*;:56-%572G,,4:,C!;*+#BEC04:4!1-=A8$3":9>@<9@H$!G#%&$9<@A/+.0&3):<;9$>AG
@r3599
GAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTG
+
)G%H"':CBF*88(-*=.>%>6#8>ECH1H#:+$'@"=32H:B#7C>#'9*$>E>;@856@-?*E2,05!2;=7HE5@6%*?8;9-<?1?C!C;4-8!"=0&+
@r3600
NAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATNTTCCTGCAGTAGAAAAAAATAAGGCATTCCT
+
!G<.3+9>)14%G4/@&+?-C>?0!FG?=B&GE+GD.8G<C2;3'$+22?1>;?32*0'B%9F0<+94$-E>(;.3*3AA%
@r3601
CATTTGAATCCGGGCTGCGACAATCAACAGAGGANGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCCGCATGGCCTTTAATGAGCCGCTGNTGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGNTGTACGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGNCGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCA
+
0390A0!$5+G(/>?E%#9A4%52-(%($A':E$+DC1&)?'6,B,*-@3)41+H0!?D4G-:B:3/;(00=H5'G!<2?:)6#F>6A=,(>;C026&(1.>'GE6*>'9GCD.449;4C;ED@$F,3((.!F,<A+'F<E7=6*6!/++0@F/#H79F=(1'?96+&@"/D*3E1.#F@(CF115**AA;&8;!'*+CB<6FE;!(D=%FF$@F)B)G;'@?;0=%E#&B<!<&-9A-!7@+CE&+@<&F,7&C8#(*1&7GC5D2'H1#1,:608
@r3602
CAGCAACCATTANAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAG
+
'+&+&"("'*#"*'$)+!&"%#***!((##!*')'('+(*+')#'#'%$%()(#'+(#)!'*$+"&%("%(((#*+*))&*#%+++*))$(!+)'*$&%**""*!&#+*%*(**((*%#'#()**&"+"&*$(!)'(+')%#"+))("(%++!))$'+)(+(!'
@r3603
TCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAA
+
2=8)##E=60@H@+/$#3?9<A+>!78B51;:*16<17#53;H74+%79,8#=;
@r3604
TTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGAC
+
H08-/(!*90?!:G9F?-C>",CH"@0/=%$$A9@CC9-+F:@<>72*+,<&D<+6B4%6>D'HE,">8F4-0DF(2<
@r3605
GNNGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACGAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATNCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCNGTGTCTGACCTGAAAAAATATATTGCAGANCTGGAAGTGCAGACCGGCATGACACAGCGACGC
+
)*2+*;9D#3'1A%'>/#:4CB@CCH<(E:,F.B"!"<7B%3=<4'2*$),CH)>%:7/'A8!)AH3/AE4(504'!#.A0F*A8*05(#=:CAH#FCC<?82A5>.!G<)<2/FA'&+@:+<.FA11E,$4D7F!4?F(4:E(#..84)0+>B.(<$/-(<@*,99?/"79<;97@192!&<EFA4(?HG5&&98C759A059/3D<?)%(?2?*1"36;;H-9+4E-85@&66"745F4DC?C/:>&&C@6C:@>&D&<02E?%;7
@r3606
NANCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGNCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGNATGGGATACGGCTGA
+
"$#%(+'!#%$&&($(&#%+$*&$)(+&+%#$*%")'$!!*(*&)$'*%+&!)+)$#*!%!'"'("%+%+##)#%'$$#'%((()*$!+*&&)'!&''$')$"%"%$"&#++#
@r3607
NNTCNTTTANCTGGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAANACATTTTCGCGAT
+
'!$%"$)%##%'%+')!&%)"*"&$&'&"''))#+%"+)#($$%+"###)#!(#***$#'()'!&)+'
@r3608
CTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCA
+
@4+EA6E3.@'/H9D/@./F9!4.;74EEF4/6FA*!@9F0/CD-4F-:7&"
@r3609
TTATGTCAGNGCAGAAAAAGACCTGGGCGGCTGAAGACCNGCTTCGCGGGAACTGGATGGC
+
(#+&!)&&(!#*(!$$###'$!!)*+"*)#%#*!'$+#+"%&+(+)&*&#!('#$&#'"!$
@r3610
GTAGCACGCGTCTGNTTCTNTTNTCNTNGNCANNNGATCCAGCTTTTGTGAA
+
'$!!*"%&'$))'#%)&#!&#%(#(!"!#!$$%$#")+'&))("+&#*"#)'
@r3611
ATGGAAAGAGTTTGCCGAAGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGG
+
=>B20)A'&;#1,*/96%%(<B97'G$">77<9C-1E-0HD?G&2G,5-964:77'4GAF=B2/+3)5BH"C466/:,(-*1A6=1C;(26;C"!(1&#08;,C?A/<F0)/H13B#=C,;"
@r3612
CNCGGTTTGATATGCTGATACTGGCGGCTATCCAGTCCAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGAGCGGCAATCCGGAACGATACCNACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGT
+
>.A+725</A.<<,.!<"BH>$<131A<(>.1&>C5*5*1->72?+?>6/,<)(1+$30+/+6>B9?C:<F<>"F#E/F1'!H?,?F@6.%26D0B<"+$%H=FHG;01EG">A52#-1$(>!C>;:?DAG5B'D;G,&<A:H4C?0$>*1*#?*DC5$&D.""&!&EA7#='>0#*@35?/2>9%D2+@)4%+DF$--CD&AD0@;0E6C77+<,50(380;;>6#5";2"5%'G,7H?,=(<2=!5C(2,.391')/,893.A@F$14$G86---<G<77,&C8D01AB*2B'H7D3*9E$3D!,22>*<B"=
@r3613
TGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATC
+
&0'F/'H(;;5;>D'"%&4=!1<(D<GE*'H3:B07/;>&/A-8=485E%,)-21+30:B8FA%E&/=F6:0"<@?##$(05H,G=
@r3614
NTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAAT
+
+H#1@*<'G&.1@F,)H9:@9:%%*).,'?"@0?<@2:$F*G=G%H$!0';9998GH<*C+"*927!/+2&!4D.D/@C.6F*%"G02!*"63:/9;40<*A;;D;8F=#F40A68,!2(<&;H;71<F,94;,G83939B0!
@r3615
GGGCTAAACCAGCGCGNAGACGATGTAAAAACGATGAATGCCGGGAANGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGNGAGNAGCAGAAACAGAAAGATAAACTTA
+
#+)!$&!*!"$$*$(")++)#'+#&!%'&*((&"%&+'$()')++"!&+("%!!$&!(%$##))#&)#!$#&%%)$&(*&*+$#'"%$(#*"#'+"*!'!%$(#'('*+(#+(%!!'"%!(%)"!%*)#&+))+#$!*'*%+"))$!($'+')$#$)))&$!")"&&#$")%(*##&%#+#%+(*"#"*#$&#*('(+&&+
@r3616
GAAGACGCGAAGAAATCAGCCGGCNATGCCAGNGCATCAGCTACTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACNCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGC
+
!"::B4./@6"1A?5B>.51<'H7,:4G@&C!/%5(=H%";:(3'HF5:+D0,3$*:E1),5;7%GG,*E%A;$C(E>-</=@?>0$2.7D*E&2'%(B0)F3'2/!(>->"%7FG>G3:"';7%
@r3617
AATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCC
+
>%81#G$GC:?)=B3->4'?-%.*5GE:!D'D"?)$*6#)E#B4(@=$$C!-5;B77$(+C-.<>7$!%A9E<BD3H(<H8%<>+1$&'6:-?2)0;"*3:".*:@59E>A&#FE=#G!/B#-81670#-D'@%D5'9E5'#G:6A"F#70G-4-<F(?3E**;HD,,/#294E<=#9&'6DE=@.+A!*/E63>4)D:%"=H7&!)0/>7,%(GED-;,#14.&A/HE<$7;@2<930!,2G+G797C'460#B46
@r3618
TCNNNTGNNGGTGCAGTNGTCNNGNAANNAGNCNGCCGCNNCGNNNNNNAACNTGGCTTANNNGNNGNANNAACNNCNNTAGCANCCTTNTTTAACCGGTGNTTNGTNNNNCGTNCCTTNNNNNNNNNNNACAAGNNNCANCNNTGAGNNC
+
!"$!""!!!"$"!$"##!$"#!""$$"!!$#!##"""$$$"##!!"$!$#!$##$!$##""#$##"#"$$!#$#$"""!$$$!#$!!###!""#!#"!#$!"""!""!!!#$#$#$#"""#!!!""$!#"$##$!$!!"#"!!"$"$!!""
@r3619
AACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGT
+
H+0;(7,07,1,='EC72A*HC$=)?*(00/,.!&(#&015H?2%A>(()28A#=(B:5#@!,9E8"?8<@F;!6?:7*/"-2H!$77
@r3620
ATGTATGGGAATTGTTTNGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGNACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAACAAAGACGAA
+
+*)B)4(=7>:64=%::0G<-$E1>--9/-%83%&":"(((1&?=;>3!D8:&(FH))G4*59*2/#291>0%FA=GH%(G',29&1/>3%9G1776:=#1)9%1#"**!%=A.!2H>4,F5/8:CCA<?%FFB5:F-E@$GG+4510HB$0*1B4BBAA#6-49<++05)),780(AH!69D?*67$4'B68F82:("$1$94777$HF%B"81"&''8?*,"
@r3621
CGTATAACCATNTGGCTGTCNAAGCTCCGGGTTGATACCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACT
+
&7#'4F==A4C27/6(=2C#697>!G6F52>1D&95)+;8<.14'!3ED%#5)7;CC?@C/308H9&H/0CA--!":=AEE,
@r3622
GGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAA
+
-*/;G$2&B)AD,4?C+#9&@B=64;>,<GA!=@"FA.26@;?H4!'+G4A0+AC"@24C".F:E+2BG/%;#:%(.;/6#;@<)7F2/5,0?-B'/'641>#.6-H)*;'5-;(9812>'<.<$<,
@r3623
NTGAAANATGTCCANTTTGTGGTGATATCGGACAGAGAAAAAATATAGATCATTT
+
#'*+!'&$#+*")!#*!%%&%((")$&&%#"$+$!&!#+&+##$"$)&('$!&!*
@r3624
CATCGGCATTGCCTCTGNATCGTTCATTCATATATGCATCCTTGT
+
79H%B/3$F(>;)3B(.2:@%./<G;2B<<352B?-+;G/-C59A
@r3625
GTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTTGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGA
+
85!5#@DG/-?8"1.-C34H*=<=73>422#1+<:.1H?435&47,0?#@2-(#F1BG81-=G-%@>8D:)2.0C7<4?"AF8:,
@r3626
ATCGCATCGGTGTTGTTAACAAGTTCATCGGCNAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGAC
+
0*?$8>0-7><$%E"1=!GA<!C">3F0&0=&:";46=)85+4;F;:.:>!"C7.!#!0:(7,9@'C2E:""17-:1*AD),&2.4!4>%.F4)""B;D,&*&5,.HG(4"2;+24)GDH
@r3627
AGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATT
+
3:F*&=)?(?7B/'3F9E!/BAEDH-$$'526?(%E)E26AC*FF-+)?B&?"8$)C87=8,-F-
@r3628
TGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCNGAACTCAAACTGTACCGTCGGGTCA
+
635#2+6!*>>?7/F8$>7C+6%B5G3A6)$-,'@54C&!.''17)?'$"E;/C<<"?&:::B3@$9G<AA6G6-!HE1!A&'0A/@4'D6?)=9*C2B=9#.8'A?!/38%.8#6B'?
@r3629
GTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCAATTTTTTATCTGTGAGGATATGAACAGATGTCA
+
A-?C=&&/<C6H5G.FB30D<&8FD5'2%?42-E#-$"2G(EFA/;5E.*>.'A=2;FF*=H3,;/G$A?<H,F&D*#.),"'GD&#+<*+(17=64F>D9&+>F;:8$):("D--*4H+.6H,+%5-2#0D#3*?"9&682@4#F3%$E)BBD'E7;/;'BDE,4"-?7!(B!<.>7503,!<B
@r3630
TATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCT
+
(F>78!+CEA)40#::C;5;#$@;B)4-.*4C45.H.<E%-'E0'9!8(,B?8=9G!**5.>G(*6A!)EB1"10!F1;,C!%):3&@=<"4*
@r3631
CTCCAGAGGTTCATTACTGAACACTCGTCCGNGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTG
+
8>*?1$$?$!@+++$D=&-9:848&7:BBBD(@53B7#99.:9@16DCH+2>2@)>F92?"&5).D+)":#C.B,"G-2
@r3632
AGACAAACTGCGCANCTCGTGAAAGGTAGGCGGATCNCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGC
+
F5?>4>'"*@?">*%/6$.@:5*3$C%=&BH>4"'5%8/>?"7+--$<=8<"/;?;:4>>/7>/$.H2)C$
@r3633
AACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAG
+
2GE"/'20/(&E-H#*<2:*F(G4?@E$,9080F#3G15";*5$28@4%B,-?#F!+#,38)&5"H<)<+H:1B?3)+>F>B@4:$2FG
@r3634
GTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTCGNTTGTTACGGTTGAT
+
++7@*<;<5;8$4.@?A="%C;"G)1..>FH):-%8DD<@,&,.(4-(2#1.#/
@r3635
GCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTNCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTC
+
A858*E/6!6*)((<0**&&:)303"<D$/?*@41:?"/,:?C:D6'9<'*!;A809.0)20.D5D2C2B6B5!:&CD;'<&A?8741=?;>B9>G*>E(;E1G5!%,D4%:#HCE::=%)7G$-GB@+G5>1=!#)>9;=%@'1?
@r3636
CTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGC
+
HE'::G/+H@$@?;*$;FFH781)<%4/%E4=*B'6E8)C54)?&4E&H'H?"!:*%(8%!"!&2F0@",&0.3H5&$B2B1)3:?1A-
@r3637
GGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCC
+
273*1AC2*G,F9-5&<C3'<>)),FA,"39@)&0?:=--E*G)8GH7-CC*%<;(-&C"G"4+9$F24@D$3;-4%$''
@r3638
GTTACCCTTCATNACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGNTGGCGGCAAATGAGCAGAATTTTAAGTTTGATCCGCT
+
$-AE3;''H=/=B5,5-6H9>9%F/"AEG?*$=>E3,6A,8*;,"8@,F0"%*(6!*"2.=1?%;-<,8)/8+,C&!1A$8/?9*&FDF@14>(-'!?D$<%G0:/"F+?=849(52#G
@r3639
NCTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGG
+
"79@D46/EBE)&6C>;8,(85>5+:&)(-$:G'?*'22@:>1.85)
@r3640
GCNNGGTGANTCACTGAACCNGCAGACGGCTCAGGATACGGATAACGGCT
+
)"!'+%#%'*#+*#$')$)$$!)(#())'!+$&'*+&*)+(&&')#((+!
@r3641
TNACTGNATCNATCATCANGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAA
+
""&*(%#(&%#)&'&!))")%+(&##+&)%$)&%&+%#*$+*)("'(!!+#)(%)$&'+%++!(*#'#!')%+$)+*&'"++%!*'&!*
@r3642
TTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGA
+
=(E=<$$-@!"D8+C,$""?505=5#BD"+".GF.?%?%A>>3E12-?"-+/.D4;":3413-0>;H"@E"=9A3EA#EC&-0"(544-$:43
@r3643
CTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCGGCGNGGCCANGTCGGTGAACTGTGCAGGCA
+
=$9;.$&A68&EB3<21&&E="9"+E(F4D"0B%=H9?B:3-G;**,5)783!A:0=AGA=&C!;"#+9@*B:H>9H5((A3#(1,.0<F">>+)%9-<HH+)-$&)0D58;5/)>/5%8+
@r3644
CATCTCAGAATNGTGCATCCCTCAAACGAGGGAAAATCCCCTA
+
81#/@"0F4+<=D1!F>=;!"<($*,#88;B#>57#EH>F.37
@r3645
ATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTT
+
B">!1("C2C6+522)/;?.*&/.E)"/'F&G@1#"+#A)E*:>A#2"'."4&(4<,D0'1BE09)8!.=H*15CE!AEB=E->."3:'!AG&+G&>:>6!DF'/HED&;1C5<H;0+
@r3646
AGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTNTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAG
+
2C:9-"9@$F"GBB7<9+B#7@3/=AD%,?B>(9&(>7!=@C$!<$$-7D::C4A+</GB4E:=,32AH4(A==+86@<$5$DG3+:
@r3647
CGCCGTCACCGCCTTACCGATACTGCTGACCNAGCCACGGAACACATCGACCGT
+
016=D?8#CA)FAB>1&!BD5!=$38>"C3=>1)3G+B@/-BC'%616"C<2*8
@r3648
CTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATNCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGT
+
;H>AB8)0""%,%C,%<:!@@*&7,*H),(7'D0>G;0F,EG#/1;4G=!,1!<D71<)F/A2!-7;31D)-%@&1D!)8#;A*5@708D;?7+=3G5GH3&.!%5:;&%$C@B)'-6+CH@"C;!4(+0+D(BAAA9C(64>.F2G6?C@+6$-7:15#(3"(.5A4>4>(>$A.=;)41):##/D//A$>4E4F(2AA)>0+8.!8DB:=
@r3649
AACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGANTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGC
+
C."+E?>B5D9<-$=-$):2"&7<5<=&2<*>,@7,<57)3)$6A;!=)$>7@3+BB!$5EE<CD+'9">C>-6CD$C,/469#)EA=:#>0/8@FDG94/G67A@3%D7;"5:BC
@r3650
GTCACCCAGGAACGTCGGAGAGCCNTCCGGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAA
+
=%5*"3H172'C;//?''/EG:D1HCD6*@/1:0=(67H>'#+=+CG,7C<="G@;*C#;,94#E!@
@r3651
ATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGC
+
=0.<$:@4"9@B5C;6$C!@F?7/B$'2&2?A71.$5?!#")=D*<&70.#8%ADA";CCFF"%3@1!*;',8;"
@r3652
GGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCNGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGC
+
17?22&+B0$&51=).*"(.!F7@-01/()2%-<#3/%@-$9-@$3><A.!*5,-$'.&+*8>*C&($B98/$+%;)87".9*?FE"?D#5D2E9FD!/A&%B>-8*F13D5;8G,F&<#2+$F
@r3653
GCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCCGATGC
+
87%(-A'"0,0EA80%'E$11/'%H$@1(H*GGG8<6<2!;G)():+?3,G$;"F511#@'<&
@r3654
NTGNNGAGTANNNGNNNAGNNTNNACNANNCNGNNCCNNANNCCANCNNNAANATNGACNGGNANNNGNT
+
#$$"""$"$""#$"!!$$"##$!#!#!""!"#!#!#$!"##!#$$!#"#!##!$###!#$$"$$!#!$!!
@r3655
AGCACCTGATATTCCCCGCTGTATGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCC
+
$A!G$!(!'+/?=!EGE%B&!=4(5H!-8!D7/<<!(.B'.172E6BB82+4D00D97&9(<1"&F*4G<F@C#,$9.1*D.:.-G='*5&,/9*H=9?+D#<04.&-;
@r3656
CAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGANATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGAGATACC
+
9E<4='<C"A0-/"/3'9@F.190"@1)$B?8:*4=1,=6%49E;-'8,66&C!9'BC3&HE:+;D5E)/G."C4$0?"2&2,D14H?GC*3!=!9H%.0?H8G<>3D-*3HF877*$9D5'2#'>B2,
@r3657
NTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAG
+
!9320;!0*''2"G1!(@$>DB%/?@A5F9((50=%0C3A<&.;659"@?*-2/F=/6A"8(2BDCC8.E!$D";-<"BBE$?+%DCHA$9D<
@r3658
ACACGTATCACCGCACGTGACTGCTCACCGGATGTAATGGTGGCTGACGTNC
+
"-.H)EFF?7?8:3BF?&5HE?0DFH=8FAF#9#H)96!F*HE<40G:"'"(
@r3659
ACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCNGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGNAAACTCGGAAGATTTT
+
&*%7*?1<B?1@(:H:4.>H"+=<H2/)BB"0&C@!-;G*$,/,&GAA)#>%,<"1H&3-5'A:4*)+'1#((63@B'?C<?%*98+F=G0@&$"7<==6D=,6D%BF8,9.<1B,-1.CB;3)9B6-<-<(6D1A)&B%?"FE3,"7?;F.+%"E8@8$7H$9EH;H02(E=7F78"E@.0CCE1AA==4,.%(@=4,25%%E4?@2?-&8FA:'9,.7:96!E"466/8C?52G/)12%>B.;-$6<-0727AC"EG
@r3660
GTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACNTTCATGGAATA
+
'(C73E2D*..-+'$%34"*,-'E*(0<7;6:7+F+20DE,4?<H3<:+*;B4BH=(1,13*&'&C$?#,*C(A*D6D,<4:7-&9(**,>&@6.B
@r3661
NTNNNNNNTGNANNGNANNATNGGAANANGNNGGNNANNNCNCGNANGTGTNCTCCNCNNTCTNNNNANCGGNTANNTNTGGNCNN
+
#$!"!!#""$"#!##$$$!#"!$!$##"##!"$!"!#!"!###!"!##$$!"""#""$!!$##!"!#!!$!#!##$"$!!#$#$#!
@r3662
CGANNAATCNTGNNATAGTAAATAAAACAATTGCATGTCCAGAGNTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGANAAGTTTTCATCACTACTTA
+
'!'#&*(%%#$$%#$+*"('%!(*!(#)*#)!#+'"!*&$("!(%+&&%(((#&&')"&!$&++$(!*(%)'*$%(+'*(+##$+!+$''*&+(!*#&"!#(!$)$#"*$$$+(+#$%)+'$%#""(!!(*!&"+)"'&$&$#'#"*)*'*'+!!#+*%((*!'+&'!!&&%&*)&"++)$%%%(')+*!+%"(($#
@r3663
AGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACNCAGCAACTCCGTGGACTTCAGGTTGNCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATT
+
@3D;4/#'9E?C%:!3A6D.-3<2-G53%C>C/80?9D@A-.*,8'A-?:FHF7)<&5=,&-%=A:(=6C(?A7/H05<).,(48@*9.3&FF&FHA"!AE0</#/8@:16-.->FA68*,#6(HFF/(;"='#0D-)39-=;934@@&#&-"+-"='!2>.1."&5/3*20,+#9AH%"B4*'?5E7.@+<:AE5H,C**2:>@'G,--
@r3664
GAATTACNCCGTAAGGCCGCAGATGAGCTTGTCCANATGACNGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACNAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCNGG
+
:D,/43,AC(>)?H;<%E4<+FH/@H>5)4&0996H%/).:>7H#+0.'/%"8C4B;3E57"*A1::-8@87H,F6$<.;:E)E*/$A2#;F6;30,AEG//BG%>48;E)F=>#C0$D+!G5,GG$G;<*'H
@r3665
GAGTGACTCGCTGGTCTGGTTAAACNTCAGCCCTGCCGCGTGNCCGGCTCTGGACAGTACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACG
+
DA=)AAC#.A"FC00E..$:A@+=E5$-;!3>#!F?2H)G>)7%.):2%H,$G:<1#H692'G;)A=2?6H'8;!-.7D67)&;9*<E;)"@(H3'$0-A.2A02$0?7&#=;<E."A<2.0!.?C-C8F1H5?=16(&F:$=1-AA1-F.6A;@&5"
@r3666
NGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAG
+
$.E0!+;'+/42#.(.*"H#-*9%*?55!8?2%G,D/,C?-(&'7&29$;3,'7:3
@r3667
TTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTNGCCTGAAGAGACGTTTGGCTGNTCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGACTCTTCATCGAATTAGGGGAATNTTCACTCCACTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGATTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTNTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAG
+
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
@r3668
AGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTANATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTC
+
*;#,!4-A#+G2'FE7F56%0FB6E2C-660H4=6F(GAH?8+?HG9<->484<F8--/%/%BE24)+8/$&<BH0"?8%C*!.5%3:.#*7'
@r3669
CACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGNTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCG
+
/FD*(E47'81#*0=F<)-81-C8178;6.13F/(0%#'(3*!-?DF%($0.5C7=E.1-&-;1H*>>0G%8,8/;2'58H@>0/@%2B2&67/(G'HG1=%7>+19#/C$5)3&;F
@r3670
TTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTNACCCATTGGATTGTTTATTTGTAAGGCGTTAAT
+
*12#::<H!*DA-C<60&5A>,@7C:,9=HD@BCGA'-F<B-#$?B9&0"H%<2<B)15$/G!C#<9-;"=5)&C=&B'--(&@,6!.$-#
@r3671
CGCCTGCAGGATNTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCNGACGGGCGGTATATTCCTTTTCCAGCGGCNTC
+
;#?)+)'F',E3F@74/7)7G$%*6-G=BH94F;:->%-!80#A<.@101/8D4EE$47C0,897$0B%79=+CAF)>F
@r3672
TACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCT
+
(9A*&E%/"3=>1A#%+B>-(5A@"!7-216D:#$D@>38=@
@r3673
CCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCAT
+
,1F&3B&)83./-@5A+65H3(E%ACF-/+G-=9*2(#,**(H.A6?6E1$9$6.(@F%CH/)'-G6<<>4C0?4@G@A-A
@r3674
ATGANAGTTTNNTANACGCTGGNATAAAAAAGTTAGTCAGACTTACACAA
+
!*"'!*'*!*!"*$%($'#)$*#+($#&+(&(!##'*""$$%+#)"%)#$
@r3675
NGGAGTTCCAGACGATACGTCGAAGTGACTAACTAGGCGGAATCGGTAGAAAGCGCCGCCTCTTTTCATCTCACTACCACAACNAGCGAATTAACCCA
+
(*59'/,)+FA821440*A%>2,H,#?#6;G%A'0',$--*FD=<E*E<?148%BE%7)(&4D6%%'21$"-7#-6"4E@!@B$-B/=:C'@6!'!F!
@r3676
CTGGNGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACC
+
E.-F./,A*'#6,7#"C<7&'06HC'.E*F@B9C18+)>7*00B!;0/H9,DE"HD.&02:64</%/&58
@r3677
TGCGNGNATCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTCACGT
+
()**!&#%+$)!!)!&%&$%&*(+**%%!*#+($"%&&'(!#++(%)+
@r3678
ACGGGCAGGTCTTCTGGTTATCNAAGTTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTANAAGATGACCATCTACATTACTGAGCTNA
+
;:4)A<2-CH<3*8D2,:H":8G#"(F9?%DFA%,>"GE(:>#)G3H;(998;7;+#??!?%9E''>@)F$+?3B,;)(0.<5>9=3+5""&&.8>)*#2+?3"<B-,;CGC?B?93D+-E)/=(8G64C#%H7.,7GG+,'&;'-7:369CD22"HF(G0G!/EAH2?!C0-<0E;9"+>"*,'(9;29
@r3679
CGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCNGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTNCGGATTGCCGCACC
+
2EH09"BACA7&%.,70'3E3%(/G)<1@G#;1%29C>/H@"$";9+>C1@5=$!@1:$,?97@AF;*96B:#?C5'@;8#&+6*<(+4C7A,/?&2D14-/9'459B,7>0%$GF>5C1$
@r3680
AAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATT
+
H+#H6">62(H<F9H9%169&?>#5<F(&87HA1!.%@402,F1!?=446-36A5#&8
@r3681
TCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATNGGATGTTCACAACCTGTATCCNTGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGAAAATATGCTGACGTCCTGCCAC
+
@7:(3@%24#,5-+(3!E$6D=F.ACC.+B(0+5-#65*0/;-@@?D35)H4B3@+HF>#6F35+;'.F*>B*/DF&H:@(,,H16-H9D3"H+=-:EE9@".*55A;G3)A,4+?@7)5F&F$433BH6==+DA?42H2:"E
@r3682
TCTGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACNAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATCTGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCC
+
<>="87&3/C#F&8)<#@#2-&B768F=<':18??*0#6.G81.08='1E8H6>$@H+(CC<-);$<,5E68)<440!'%C82(#?5+A7:)-#$@%,.(@5&0>&%#G+&;=*&.(>-2E>H%,+AF$>:'(9>9+7,C#"3/*8/*$&;=C(.H-?,5!HC%>1.=B:F*":!:#"A2+DG=<#48AFF@&2#7?9!:+3?A5#@5&)C0>;?32H1:1192#@59&-)%#3,9.+#7CF""3A:,)9%37H)G;EG9H;6=2H">
@r3683
TGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAA
+
F5DG=>$+8*&/&>7.7(()',3FEB'FD->AG,+-9E'4303$("%.$<42'"5$953"H!%34DH?F'"@(F?6'!E6G;0<H6+CC8E'1+3:$D$C>:6D?BEAD7/$/$CB@5=1)<
@r3684
CCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCNGGAATAT
+
,9F%$!@G0'>A>%56H0@H2++G13>$/@1C'7+D3*4@)@/"$3H26G7$&<,&6:0?%%9$'?D"&=3+&5.A+;!!"
@r3685
CACCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGAAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGC
+
!"!+%)#$'++(*)()#!"'%$*!%$)%*++*"**$)"#)##*!&#$"+**+'!!""*(&''$(%#%'+&"!)++)'+!%#$(*(+*#"&+""*&')$
@r3686
GATTCGTGTAAAAAATATGCTTAAGAGCACCATTTCTATGAGTTAC
+
D+%)5;(A$,#$EG=+$?B-3?)$*=;9$E*7%6@!E7(:#0B1=6
@r3687
CGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAANCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTNTACGGGGAAATGCGCNTGGGGTCACGCGTGGTTTCGCAGGA
+
EH=%4&D3H"A+<7EG):-%:A&8=)7F%:-"(D1>=#G9G>-%6H>&E=<D5*2440=-H"@4::%+9045G1,+!'8'9-/9F59&+.H002D)2<,<%H)>2<E>%./?@4?><3<6024E2?-2C+8%552"0#?B49-7@1;#
@r3688
ACAAATTNNNCGGNNNNCNNNNNTTTNTAGNNTNCGNNNACC
+
$$!#$"##"!"##!!#!"""!"$"$$$$$"""#"$$"!##"!
@r3689
CACGNTTNTCNNCTNCCCCCGACGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGNCGATGGCTCGCCAGTTCCATAACNTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGA
+
%"()!&#!%$(%*&&)"!)%++#%&%#")&%)("%(!%(*&'&+%#"+&%"&%#&(%*&#'$*$#!"$$"&)!##)+*$!+'%('"+%'$&#+#*'$'#'$!))#)#+)++$(##**+"!%")$)!*$))$$%+$*!#+&')!'%"&&$"%!'!"%$%+*&""**"$++''*##%$&!!!**%*!'!*(+&$$
@r3690
NATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACNTCACGAGTTAAA
+
(3,G.4$6=5;<*,3<7F.HH82(:A/)=)-14E/$@D=H)FC'DB8,2&.,(0<??7B@+D+&7&9$;40G4>+=@3@8/AD,2=$9'26')!8E3+E'+8?:B08B'G;DH%9>2!9@2BC$)H
@r3691
NATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAA
+
!+&($&'$!(()#!#()&+)(#"&*&!'"*$!&*"+&+!('$&'"'*"%&*##**)+$&*&&(*
@r3692
CGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACNAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGA
+
@;HFEC;>$<,/#&072?:.@1"B>,3D4DD<&AF21-,,A(44<9=6E:HH7>263#;/<936:AG.#7"6&0>3#!*A-6?%$@G5#)A(<8&/*G30=0AE:G&D7'(.%E!-"&=0$98:8A>561?=<E'/!(96=$$=9
@r3693
AAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCA
+
&AC8C7)505'1C;<$1(7:'#B.-%%>-8/G#$2>H&&84?D55%
@r3694
NNTAATNTCTGCTTCGAATGAGCTATGGACATGCAATTGTTTTATTNACTATCACAAGATTA
+
!%""*)#$$+'*!!"!*$##&&)!!%)''($*(#')"&(&!"&%)*"$%(!"#+#"!!!+")
@r3695
NCNAAANNNATCTTCGCNNTACCACNTGAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGNTTGATGGCATGGACTTTGAGCAGGACAATGAANCCTGTACATG
+
$#"*($"$&*$""'&("#)*#)"%%!&++&+#%%++!)%'*)#*)&!&(#')%#''*$#+"%!"("$("$&!))#$+('#!'"$+)+#(+"%!('"$#'&&%&(%#((&!)%%&!!!&&*"+(#%(&"!$()%)*!$#')
@r3696
GCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATG
+
F#99*>+9"B&@.15?@*4=,4.1):37,B:8$F'<,1-G"A2%1*&>&F%7=.@>(D'.$%)A8=61@,3@
@r3697
ANGNAGNNGATGTCACANGCTGNAANNGGGGTCTCCCGGCTGTCNGGTATGTATGANTTTGTGGNGANTAATGCCCCTGANCAGACAGAGGACGCCGGNCCCNCAGAGCCTGTTTCCGCGGGAAAGTGTTCGANGGTGAGCTGAGT
+
$$*!('%"$#)"&)$#&"%$)*"**!"&%")*$&$+%#'!%'"(+&&"(!'&(%(+)&%"*%"($+$+#!"'&$&#!)&(#&!"*(#!'#()&'%"%"+(*!)*+###'"(*$))$%($)+&!#&+#('"#"'*'%)"$**%!*'$
@r3698
GCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAACCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATG
+
-).D8,5*<4!$/:C>4<*$;B$0*+AB10)H+4'%)1C!D6H;(:%9?BG$=>#C=/G$H"B@A"G>9*A%+#,HA'=F&6"@'>7C@)"7D5"4&8?23@77-B<,A<EG7D)@4$":&+00C$=;A;33!:39,6)A;&D,6/7.=9
@r3699
TTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGANGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCANGCCGCG
+
+%#'%$'##%&$$$)''*)&')(!"+"'"()*''#!$#'+)"'%&%*((+#$"#(&!%!*++(&!%'#"!++"+%&&'+*%%'%&)&*##")
@r3700
GACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGGCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTAC
+
H>(G@FG%)G9*<E1$C&BD,G"0?:95:92<;"/:&9&?F708"085G;#=97#5=2F=+5<!8G"$<$)9%09/A2?#;;!.2C?!0E.H'D.#H)#9#3#"H3C5:3!E58-.D3B/**3*-C)0&FB7*#DHA'+F,'"*%F0!=7,C9BG.$1&2=<;9/>=-D:B;-%5&?#E2$8G/(HGD7
@r3701
ATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATTATTCCTGAAGATATTAAAGAGCGTCTAAAACNGGTAG
+
(*#;'*48(9)3'#HCB11)>.B1-D@=*<56,G("C<D+=760C'=BH+3''0C/'B..?-B%G;:B$15>'#)7C6A#.0><:7?6>=*@+%09:%,;4B+D(<CHCG6B<2/4*.%B5G5&!32.>1$
@r3702
CTCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCC
+
&B8)9>$2#73:,;8@D"*-A%H*GD-7?-(9&7#.E84H1B
@r3703
NAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCGACATGC
+
'@:>0H'#*#-=*'G@6-)C?<@-'%!:.2G)FFH7?F?E3+6#/&1@=+<43"
@r3704
CTGCGGTCAGGTGCTGCACCGCTGGCGGCGTNACACNATTCACCGTGCCACTCTGTTNGCCGTCAAAGTGCGCCCCGTTATC
+
$::=8F;31=#=<@C&9G18'8'A(DD8B,7$0$<BA>BC"43$?E.E#3;-GF19,"B!2=C.E?EFH!&G"0$<:*BH)(
@r3705
ACGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGC
+
";&$A7+G9/1E;4&&2:3&*F@*5)/&-A%F",<%-8?82
@r3706
CTCGACATAAAGATATCCATCTACGATATCAGACCACTTC
+
G*'@'7*00'.6<6'')+=6;)-E;6H.>65*'$"71,,8
@r3707
ATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACTCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTANGCGCATGTGCACCGGCACTTACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTG
+
91G/%*2G0E>$18&!!2+05DGG<7,;,<H9.-&=7.,!)@,C(>%0<2H<6!;8<BHA9@'=,+=$:1"15G8GB1A-?#!16"2B/A8HA:+-*9&?6-H<D>",F".,)2';)#$!<6%E?B"-8@96B&53*,B9$/@14</EE($>*/C"?(36D@C?8;GG;6A#(/H+;3*H:.8@1),E2E'%)F668,B)8DFC18!72D7/!$&;-,E%2G=4:$G&"*0+GH52.!EHA&+G29H367'"9B*G0E/7/%.D8+EA<,E509/7#E;:CFE@H.%*,=D40"",,
@r3708
CCGGCATTGTAGGATTTGGTAAAGCCGGCCAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAG
+
C6B?FD,A!8A&<'9,*(H$*$$76*:C-*'3+(:$G1$</8H,*>1;:(01;B!.4%(0?B$0'%??DH$!$
@r3709
CAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCG
+
>A!39'7:2029$!A7B47FC-?7"3B($1:>%F36**D?&$;'#G;-H%>D<((2<'C&,1-&-H$),!95F7=EB6?<!>"%&H)#7A23CC.C5#F>7?3.2$3.161.09(+#)-0=/9/#3F&##B$3)8A/C=425<!"A=8=:64#'84*;.,>#)FH*+"9
@r3710
CTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTGATAAGGACATATAGTNCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATTACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGC
+
HD21?D,,8@.E22*DB3C1@*@';+,>F*-F74.).9=:"<0@$1E,+1D"<55(6,%.&>B;)7H*="G9";/GFC@.<03F74===@=7391#(,4C2/"8-:/0:&"B3C::?:2B')'6G25&5#D!E&%%(@A'B82(E/</19:"$4))G1B=:+0992?7:-7%!+)C5"*5&D<*,A>D,2#%?3/AF)#0-1;C6(@?9/@EB&,33)+6?8?)<&EA/51;$)E/9.@;0"A3<-3&1A2##>9@)7%#&D7%,"&@+$G?%)A@H4>
@r3711
TCATTATCACTTTACGGGTCCTTTCCGGTGNTCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCNGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAG
+
<6-6)D*H86BGG&#F+*A3H$>8-:G$F@.'B16>3"H@A7G:1%7#;3G;>B!FA%@>'H*A?.)59&6?()?$@FA)5**-ED@7;/AH9=4!B51??*57F1"H36<G4,
@r3712
GNGACGNCGTAGTNNNCGNCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTTAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGC
+
"!!*('&*&!%'$#!&%#$+'"!(&#"+*+'"'*)")&!(!*))!()$####%+(+'&#&*(#)"#")&#((++$#+(&#&$*#**&"%"$+*""%)(**&*#%''$$+
@r3713
AGGAGGCCACTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGAT
+
?+./'2G,7;9E5++5&C#*-DB1(*3)7=>98@!8:5%7$<=$9&@3>.2--,F!.'-<H%E:5+*80FA
@r3714
TTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCG
+
/H:0H17?90&2;-=:)8*'>38.>+9-4B.,"*5(>-869%C"H,"F!.1<59B@3E<<HCD(B9$F9<0+16)EG"9DED(%$-?$#7D97;%!)9/?.3AH"@*55,,@3?D0DF,4C>2=06&'.0C:;5A=<)4A%:"F*G2;B"?"3'A,/"*F'(7>&-4
@r3715
ANTANNGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGA
+
*!#%##+"%&$$)&'&#)$+%%)'*#*)%($!#%)!(%##%$$%'#'*%*+*#"*#!*$!&$!!&!*!")&"#'"
@r3716
CNTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGCCAGTGTGAAGCGGTTATAAATCTGCTGCTATCGNGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACG
+
#!+#(""&%$+!*(((')(%+%)%'##%%"$#"$$$'&#!(+""(**($!'"%!$'$+&%&'"+)*%#*&)%"'*%%&$+!'%&+"'$!)&$%()$+!#(%)'&+#*+!#*%""%((*#$%+($((&)#%+)$#%'%*++%$)$('%'"#')!)%((*&)'
@r3717
TCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAACCACCAACCCAGAAAACAATGAANATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATNCCAAAGGGATATTTTCGAT
+
*(:8(C8-;?:'((;+F,6(#<?)&-BG77.6*='1CC1;61>4+B!0@2/%31G7@@'*D/)H6+(H>0/A/E8D4@>H@BD22(H/!2E&+F8#5854G<#%2?9F-';%),$;H$D-#<$*4+/+9)=2+'42HD
@r3718
CGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGT
+
)C7;9.<4-<);4&A=1?&7?-H2!&-C(4,%88H!9::5FF2"1:5F
@r3719
AGNTTNTGTTNCGTNGGTGGGATGCCTACCGCAAGCAGCT
+
**!!"#$%("$$%(!)&+!)#&$&*)+$))#*!&%"+&$*
@r3720
AAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCGACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAG
+
H4/B"3/0,C+G;F'A;B!%2*<@F,%DH#1D"4,3-?89?*46;0.1(2/<&>,9>+3C09"<56;"BG*1)D#:>$"('D8D$(G',E0&FD1.)50&/.3H8==$6!;0H,EB!),A1//D1'D'2+5G>9:7>02?D.)5*@B47A?;'$:63G<FA'+;<585*D#B9A!=A;@?$G9)6C5F!"98A!G,E:0<4?1F-%&0BG
@r3721
TGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCG
+
B2*FH":C;E-(.<+E9.CC3/F6>>HB##C+6>118=/-'A+349!5H@+A:
@r3722
CCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGACCCTTC
+
B)73C0H8$!/-A6=:2$3+CC9H4"0*124<(A->;F/04$2.$=6/<<7D,19"H/!+@8:)'7,7D/F"BG=11AE:A(
@r3723
GCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCATAGCCTTGCTCAAATTGGAATCAGGTTTG
+
@.>8@;>3+CC97B3B(*-@F<2H$7",8D>G<>7@#$HA006H.&:B6G?#8@(8E--E723F$?!6<H.A;?7H?F;:>HGG/9>)-E00)DB"2%.0=
@r3724
CAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAANTA
+
E;?/9'>:=&0;E149CEG:9/3)*6?52A;!;>#!&(@57B!)A;FA+!8?13F0>$A@;1$D)E!,*59C.""
@r3725
CTTTCTTACAGAAGGGACCGAAGNCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCNGAGAACAGGCCACCATCA
+
*#+++(#*$'"!"(&++'$)*#*%%"(%%"'%('(&!%&*&$+!!#)#""!###+%")%&%$*!))*$"#*$&%!'+!#)$"%(!'!'''+$$&$*
@r3726
TCCACCATCAGTTCAAGACGACGCANCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGAT
+
3$*0(F@.F-B;70;.7/+,G9)%0>1=46*DB0A*G?<:+(H%;+:;/6&36)#3>;.;&18E;&)6(:=DA&-4'.$:>*$&1%*%4&5*;9*=!#%")D%'?026>"
@r3727
NGTTATTCTCCTCACTGCNGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGACATGGTGTATTTGCCCTNAAGCACGGCAGAANCTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCNTGTTCTGCA
+
,9A8-D<$98,-:;<20:E1!,:=''!A/41/9D,<BA/+-C";B,%#<)1=>+0D844=0BH(2#?$&G1);#%"H$$5#B!@2+$G$,%-!7-6?1;)6!A7E&-+:9H$@+#*D;2"(%828D-(#.8?:=5>BC.A/;5,CH!
@r3728
NNAGAAACGCGCCACACTCTGGCTGATGGNCGCAATCTGAGCCTCACCGCTTAC
+
"&+*!&%)&&!)%%+)&)'()##!$%(!"%#+'%$')+")"#&#(+)('%+!'+
@r3729
CNAGNNATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATG
+
!#""!"$+'''#&*$+'!$+!(&(*#*###"!")#'(('"++(*##&*#(!))&*
@r3730
AATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCANGAAAGGACAGAATGCGGTTTCCACCACTTCNGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCTGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCT
+
:B=()E)D5#01C:%)'E=,DF7;2!+8>?>3$?"(H+"F90E+<1(.G3A3-<D"4100D+$CGC!$=@3/.81/=5(1C0,@#+F!;H"C'H;&5,=87F4H3?$H;0H'FG::7"-B.%C5D2)DC5!!D;C:94$-27#79:2582+%#>9H4H#F+C3B(E#.AA)/9HC)?/?;?$7?>DE00;#$-=59G!,!1'60:@8$&GH!2@=;H<&#0.&#7.#C'HE:"DF5?@4)%3-7G)F*
@r3731
GTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGNGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGNTTTCGTGCGGTGTCCGCGGATAAAACAAAAGCCACCGTGTCG
+
G"G@F&@@(8,=,.;23-.;/.78<79DD(2<?F94C?;9%A@4%()>D*C,5(5<8#A4FH;6B>CC,6E.5:91*!+!4=3+28#GA"A;0,B!)"8,=#B;1&"11&*&$5H!#6',7-52"C;@,83F@10/D9&5.4F1F>+2(&#<5
@r3732
TGCNGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTT
+
++E.<$:4,32+D7;EC&B/FBC!,6$E%)55A0%&A9A'6=)6&D$E=G<-7>9>#D,$E/5<29C;"(35!=.A4?)$</5,<
@r3733
CCGCNCCAGAAGTTGTCCTGGCATGTCCAGCGGAACAGCACACACATGTCGCG
+
&*'"$'+""(!+%$)&"$!)+$$))%#&"((%%'))')"#"%)"$$(&'*""(
@r3734
ACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCNGACA
+
,9+(D#=#%51@B75!4HHCA/@")EH%.4G":.#?,;2E#+B
@r3735
TTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATG
+
+&!!%#))%(+#"!)#'!+"+#!"!&+'!$))+#*+$!#+*%$+("$+&!*!(
@r3736
GGATCNATTAACACNAGTCATTATGACAAATACAGCAAAA
+
%('*!!&('*(*((&"+##)"$*$")%(($""&%&$"!%)
@r3737
NNNGAANTCGTGATGCGCAGNGCCGCCAGCGCATAAACGA
+
%$#$#&##"$$(+#(""()&&"#!#*#(#*#&)'')*&**
@r3738
TTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGATTG
+
'%;;9-$:.:E<5&B$;%*7>3/C95&'$E%4><C;1).#3=?65+4B#
@r3739
CCGGAACGANACCNACGCCGGATCGCCCTGCTGCCCCCACGAATTTAC
+
%0AA6EEAE0AH3,->!=8F@(A%2*BA<5";&0-6>.3'1)93)6>5
@r3740
ACCCCCACGCATTTNCCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGNCAGTTGCGTGAAGCGGTATGTNGTTTCCGTCGTCCGGGCNGTGCTGACCAGCCGCTCACTGCCGTCG
+
(8+9699E1D+6A9?:-@C+6;?%318@;(;&4=#/7H.D6E/@$2>3-(C%$???!6D+AC&2/71=5"A8=9/0+?E)=6.1+7"8=>E4(*).1%=H.&!>%.'"!+5+F:?$
@r3741
GGTTTTGCCCTTAATGGTNATGTCTTTTTCCGTCACCCAGCCACCGTTAC
+
>E8:B3%;<G9%2/G3F6A"51HD+4CGCG74+:06#F,*"!7;0:>-D>
@r3742
AGTTCACCTCAACNGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCNGAACGGCGCGCCANCATCCGGCA
+
&;>(%)?@1D".'3(6/#&*C,<G?'DH%19>2D!%@%8=-9+(,B%286'>17!##-?3'8D$<)4=%52;G*5
@r3743
NTNNNCTTNTCCCNTAGANANCANGCTCTGNGNTTGCTGTATGC
+
!!!$$*!*!)*)&"&&&&"'#%("'&!'&'!!'%!+&&'')#'!
@r3744
TGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCG
+
<@0*3A75*(>+>)?AH/+3(C!>465(C)625271$F*F26,FG$$6H96
@r3745
CATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGANCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTNCTCAGCCAGCCGCTGTGCTTTCAGTNGATTTCGGNTAACAGAAAGGCCNGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCC
+
>2)#,#EFF+&C.#:6>#00D1/1-/B<':,6)!E=C+>.754!4A'F)0<5=+,>:&9)C#1E3-F43%09,3@*G+'92H-*8F/.1/#FE<>9;4:37G-BA6E,;H%ED<65**)>!4)7B>E57H?+?-/.6#@4#85C45=*91@:08H8D?()2?%A7F*2="#1#"!%!A&%+F=&/:66.3CB?)D+7=AE->5-)<-C"-E:#+56G(B:4+AC=F"+CG7AA&;7.F)3%4!&9&//!&6/,!2>)(.:<59*>0+'3@A>@85>#!CE8<#8:7@DH)
@r3746
GGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGANGTAGTTTTTTCATTGTANTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAA
+
H%+C7</E@;BH/D4E($=%1);E:6E/1,;-?8;=)A)8C/<8':$9;?5B1)+!3B$E;0@C(<'9@&02A5<")0()*%*/C)'@4!#)7$F+1E%1?#G08+G!HA=@*6H8CD')-G;42FG.+*413#=#?2*D,?!#%:#(&-H)&6"C.9)BHDBC8+B94>(,'2;-?=,3$8,B(%9*AC7<@##B@)'#0@GG>>H0+<<EA)5@)?2
@r3747
NTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAGAGGTGATGCCAGCGATGCGCAGTTCATCGCATT
+
$%7?3)+B7B-42$8A01F%C-,&-20F#?%7HA5/%,6C7"4DH8@+G2'0=F2=DGC59*F#,2==H/>>)9@*<!6@;(*6A=27%"A!4"@79@
@r3748
NGGTATCCAGCTTCTCCTTGNCGGCTTTGAAGGAACGGAACAGCGCCCAGCCNTTCGGAT
+
$++!$$"!++*'(+"%+%+&*!')("!$$(#)+(#*&+$(*%+!''*"*+)!+!$'$'+*
@r3749
TAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCNA
+
8$4"/=2"<<,*%@8E<G:G0*<66(B9;.4!,01,/59B=00HH!6/5G.A"E;8?6?/F
@r3750
GTNTAGACACNATGNACANTCNNGTNAAGGNACTTCCATTATTCTCCTGAAGATAATAATNGCCAAATAA
+
!(&'"*'(%*%(#'"%('!'"'!%($%!$*"#(+"$*!'+%$'*%%#'++%'#%++)!)#()#((%%!($
@r3751
CGNTGTTTGAGTNCGGTCATCATCTGACACTACNGACTCTG
+
'#)F20E&@B:741-B.>C'57/7!&>5*>F:*D;)#$>"$
@r3752
CACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATT
+
D#,223%<%C:<7D#:/5.&;+-D&7668.?A@.B6'%,#A.GE%(!&;=E*!G8::7>H"-
@r3753
GCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTAAAGACAAACTCTCCA
+
*)%;0##5"!,?.,#;8A+"G248B76!@5H@06)0BA.2AD?)*/GB1>4D"CA83/<,-3
@r3754
TATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGA
+
4,C%F3=17:85*=*'-0;98'+=>E6(>H.$>2&<3:.$>B@7;#*5E"A;,#)+EA$2A.(4H2*E/6?G6-7,88/&---.5F<<C7B:;@0032F75"A2&%)#*.<:#-7?#1>-/<C2@;<"&,2)A.88FBDC#3
@r3755
ATGGCCCGGTTTGATATGCTGATACTGGCGGCTNTCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATNCGNCGTGGCGGTTA
+
A78-6**6CD(!)4>5A+18;<=8*>A&01(G")F*-1A)9CAD;.'A<>7082&;6(,5##,9;+7>4)(G=:2!F$,(&G$B&42">G0#$%-F;3*D="5>!;=),%0>65+A5!+2>)A(<"B)H?E4,3;+-7.@D(E0,?C=3E)/F;4)+""2F",8#G
@r3756
AGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAANCAGAGGTTC
+
>:C'-C8=C7BG4B10,1H7:5?#(H&=+?4C:078@9B%A1>-B#/34#
@r3757
ATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCG
+
@D,*)G24*EECE<3A!!6+0-CG0@2.0,5;(="C:H1A!(;'03+EDHGC)+/C%8?(9=3@0%
@r3758
ATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGNTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCT
+
A90>C'1*&<C'G,:)AH;E;0*659">>"5&221)A<2-?!;32,5%@DC:E%<F$:7C)'6(7F@GF6?G&8?9(!C2H$,0/;;).$.BA%2-;@$*'=+G>)H61:<DE%24BC%>>A&)"<&FDAH4#%7+@"E!*E+'9;EG.3%94!:=88B*G4>(FB%D#76?*?59()5+'86@&+:B2#/A'<534
@r3759
TCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTC
+
C$%G'>&FC%=45)4*'6!-,G#9$8:<!,:3)67'%4*!%'%<.+&)(:20-7$3<2D
@r3760
AAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTCCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCC
+
=/6%?(>E?!D<<932G=F=0=7'D#=(<2B@?EH-#+'$!(A22"#B2>?$=H?@(*'BC&3#CFCC.E.EC9
@r3761
TAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAAT
+
719.GE$A1:<)1G,*$!23?&/:&G:1%!"=H-H.F?.)%@),&&?E&*@3*F9=&%$6%?<35<@77,4';GBB-2
@r3762
TGTTGAGCCAGGTGATTTCTGCATAGCCANACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGNGGTCAGGTGTTTTTACAACCACTAAAACCACA
+
E-/*2?=1)E%)8>!"G(*A'+0('$E%<FF*D$AE)/-0=F=F#9#$EBF(B81:5%*'7/.'*E@@H$0422")-1H#CD%?46+7>G!""G<*3C.C>2&(=E<:
@r3763
ACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTANATCCAGTCTGTGTTTGTCAGGTCGAGTTT
+
-8"/(;G,,)+=BDB2,7).;,F-(.41&8>C%&'0>#;-"C$$B-3=*'5&B23"+,$":;9"!:')9?GC9%87G82H>AA$F834@FG/'4F
@r3764
TGCAGATGTTCTTGAATACCTTGGANCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCCAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGT
+
7E@)*=!(G&=18-1<E>,-294A"3DD?,5;D2=.$'26478F+C&E(;'6$%/,<G11D)%38,5D).)-2@.1(>%<?442H"'C-/E>?6//EH(D8/);9/C"D0,!AE@H)->03E(AH=$9-$&-0=+3,:@#'0
@r3765
NTCAGGCTATTAAATATTGCTAACAGGTATCGTTTGGANGCAGGGAAGCACTTGAGTGAAGTGNCTACTCAAAGAAACTCTTTCGTAAAATTTATAAGGAAATATAGTTCAACCGCAACGTT
+
!,"="#?/)60;*/B%)(046D9-4,8@//E@/<9,!)/)6<(8+7(8'8'07'5F)60.=%-":.6-9!"5C&H0,:77*<>B)540;*7=D5HFG@-GH<$%9E15D2;&*F>):*B'29
@r3766
GTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACC
+
**>3)8<5DD55*@/2,)%%<")/-!$0E4D<@360@F'0E++#0D:.HE8760
@r3767
CTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAG
+
.<?@17$BF4(>0"BH4''/;3/.;A#:#==<-E:E)*-9-+AAD+;?DH@?18:$)G6:@B>9<-C!#
@r3768
ATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTTGTGCATTTGATCCTTTTACTCCTCCTAA
+
?C4BB8%8'%"7D!'383B-/$./@F7H6+"+H6#H(3.-#9.!C(%-78$4<E"!:"=C$&A-+>>7.**<4+>5+E?G4*,
@r3769
AAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACG
+
2884*65&7A91/>C.F05%2=C??62'#>E<%)'50A0.#5A$-)?"#5C>+6.H!/-C#*
@r3770
AAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTACTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCAT
+
GG!-/?@.FG?7)<CA96E#7%E.?HE84/C/;HGC'/!8*H73"@.<@00;77A7G$<(<?+C;BGED#:49F%@4B.(2F,<AF39B!4%@6#AE=':<5*67&C;15<)'"D>E"A;<&(27(4)"A"/,4H.))0F$8!$2.22.;6G5(D2$E1;*9.E;4'BE'876<9!/>C44?;1+$=F4,"15)90:HD4!F'AE
@r3771
TGCGGACTNTGCGGGTGNAACNNTCANAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCA
+
%&!&"!)("$'$*&!&)&*'("&!*#%+%''')*+&%)"(')&**!(&)"#%$&#(')%$)#$($%"*")'&%!'!(++%+!*"(*&$+$%#&+)%$')
@r3772
CGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGT
+
/?A%9?/>?AG7(=C($?%;,=1-677!1+'AC<28%68D:3!-)()%)888B&%'/%!B>=AF)="AG+/4)(=.9.?<134B<0A6GF-,6;7D>5/EAA(FEFH759/0"8/H@.:,39F->0*
@r3773
CGGAAAGAGCCTTATTCAGCGCCNGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCNGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGANTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATTTGCTGG
+
5*@()7!<::-)?G)AG:@>-E'#%'F=(>0@0/C5(;1B*E,4&%.,$'F?%6#!3/G:6=:;:<'3,;;=73/B'!>47+G(530(5>C,2<3(/B?"<;3C1D%3G#9$"5.*B).EH1?)*?=&2$9D"!@1GE2(@@$AF8H,<1<6*.EE,<(B/AG=996#9AF*,33:82;*H(<:7-!@E+9?2D$;7;$:,$#)8,1>2)9F!EHE#5E,-(2F/AG&?97/8G@87#%888577G?/>B<B
@r3774
NACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGAGAATATCTCCGGTGAGCCGGA
+
%4B27E3D)+%+D?B"9>B>"6:2+@,=>(G.<!'9)BG/C6+@*;.60@D*?+$D'9+23<<F,1AAE"2F/A+C))%1E=.%@:5.0!;9##%2D&+/F$3/1*8BA%DF5=5F6<10"@!CD9D
@r3775
TCNGGACNGGACGTNNNGATNCGGCGNATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCNGTAAAGCTGCTCATNCGAGACACCCAGCCCGGCAGCGATATACCACAGCAGTGACTG
+
&)"''"&!$!"((&*!")$('%)'%)!%(+*%$$!'!#+'''&'!&($*+&%+"##!($'%()(*&*&%*"+++%%(')"*$#+!%#(#(#*'+!#$%#'%(+$+(+)"#!&+))%()&'#$*+*%'!#&%'$%%')+"*#$!&%*%*#$(#&*"#'!!""+%%)&
@r3776
TGGNNTNTGCAGTGACGACAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCT
+
$**#"&!+(+'!%'#(+$'$**'*"%*++&%*%(%!"$#(#"#!)'!#*(%(""&'("&&&&"#'(('!)!'!&&"$$*&'"#(+$!)'*)(&&++$$%"!"&
@r3777
GCAGCAAATCCCNTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGANTAGAA
+
:$?AD$;(+*<81(02%#;'E7C+.+)690C$8'"E+DC+G9GF"".!/&0?EG1B*B<-H9&?<@:.E?&)<.;)*>9':-B&*152C!
@r3778
ANGTGTTTTTATTTGGTCCGNACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTA
+
)#%<>.1,AA0'H%'363)>@+/)-/96<17ADD'8.>!=;>/<4//.5*,D-2D<"+*H!F!A+7';-(/")54>H2-#@>=3H"(1=(+&8*9D"(!/3<8D
@r3779
TCTTCCNCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCC
+
D$:G.8?)/:,:*;A5"'9'H>5"F/7#@46)8G%<FG;2)@<CD,<"E!F=2#.0EE12),H@B/>'(?!C
@r3780
CCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGNTTTTTTTAACTA
+
$,>/$C::*0E1+F8/#&B,F207'H=@.(8D.A=37>)#/(1H37))'2*6,A)*@?.G6A
@r3781
AATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTA
+
+$!)('#&%*%"*+)!$+('##&"(+)+&&"(+!)(+$()*%$+'"#*$!$!)#+!"'#$()"&$%'$'&('
@r3782
ATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAA
+
8@&=B!B.29+-'?3;50<C%:4$>3(('!G"6C4$$:CG/7:E"F+HF6F6B53!G62$D9.H#F>,E86B>5.>9E)4H9"A(8$&25D2A<>+E)&H**54(7?4))%C08)25BA(!&8=E0%20"58;/
@r3783
CGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCNTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGNACCGGCGC
+
'F:='*<"33;$G'1:"B?G4F'(+"+%.<)$1;%H'&186/FF(?B+B;'@-E!,>3!B3#'074?'E=!>B4-5.#28(55=1!H+<.!GB64.*F?,/C#9&55>&%:%=B'&.-2)3!%%;8:!D(<BA?:C81GG&1&B&@H6!93#9G=A+C-21:+,@),'GD@CG<.&G->9"4&!'3B*<($1CB"&/AEA>50CF)A7E&30=11/'*53<0
@r3784
GNTNCNCGNAAGNTCGNTNNCNGNGNTNCCNNNTNNAGGCNNTTNANNATNNNNANTNANNANGNNNATCTNG
+
#$#$#"$#"$$$$#!"!###$!$#"!!$$#"#!""!$$#$##$!$$!#$###!!!!!##!$!"##!!$"#"##
@r3785
CGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACANAAACGGCAATACACACAATACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACANTCAGACCACGCTG
+
.5)89@A?-%929:!41A;3*'D/","*+$'9$/%B#2%8'(5G/+#>!7H>'@!<*;234-=.>>H!"<@BA.&!,?@,D,<G9";$<BAD6A$-:!-)<<-*8.8<+6%?&"7&?DF6A%8)&1@>%B*>HFH,;@/-H0)B)"D7A1"!473/D+',4+>'$F>
@r3786
GAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACG
+
C37#*:=$CA=D7>"&:?3+$0<A9;+#GG#/$A1*&'6493C#%!CF6;1:>9D,..DA,=AG'FD+A&C!#&:/B1F7(#(<>>'*F71:!D+$8<>@>H==3$:;G'4$=#$C3#@E4+:9"9.#.32$1/?CE#A(,37).?(:H%?23$>"-C(B?.F57!C(<"EHC+9GDFD=E>>&53%;)*<0>G,?:*:#3!%5)8E,++B:=<21*=E.:&*#@E@E(;@;H0*C91#D<D2B1!C@G(&)3,=7/?%?B5-.B'#D@(/"F4?+?%C$43/:D7@(*H#.E/245D3HB@%:&2("97,FA2&3A&!4G"&:?14#74/"2*F.B
@r3787
TGAGTATGAGTACCCTGTTTTTTCTCATGTTCNGGCAGGGATGTTCTCACCTGAGCTTAG
+
'@'F1)46::419GB.(8E2&-E%+D58..<=AG.,$(>9'3/=H2C081#H%*6%&'->
@r3788
CGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTATCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACAGCAGC
+
CB>&-F-87?/%AE$&)-E6>*(DG#,B43A6?E?'H/,&>18*,,";B/25=@:2(EBA-,#;@@2&1:/>6'H)4B7HG;*:.<FA.G$GH;-"((>'AA1@$:5EE0!=,!5D...*F;D
@r3789
GGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACACCAACGATGAAT
+
*9G6C"?44?8"%F.?;.),$$69;<GGGA<8.##2/<50!-H=D0F$>G)#.1*%'>%7=:
@r3790
NNTTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTNCGTTCAGGCCACCTGGGATACCAGTACGTCGCGGCTTTTCCGGACACAGTTCNGGATGGTCAGCCCGAAGCGCATC
+
",?<F3:,*E3@B$G>@9,%!G>.?5'D!65*7G%@+=3+2*2?>H).%3H6>2<8435%%-!/#23F7F5!F@G!9B$5B(G@:6;44D1A/#&E;?=%ED,@#E+9'7,1*1=294C94
@r3791
CTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGNCGAGNCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAG
+
G8A:->&HD%?.(4&6=E5$:@B**E$<G:9#C%43!@267=9(4%4H(D)C:>$;&HA$3>=,B<-=.+/(7H"+/!)9''EG$)'#:%)/<A%@7F.;@%(H*9D@#.AG<4#-3D6115@2<22)(
@r3792
TGTGGNNNGACNTATGGGAGTAANCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGANGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCGTTACGCATCGCTATTACGGGGT
+
"%**$!!"*#'!%"+*#(&&(!$*)((!++)#"')+'()!%##$'!%*&&("%(&%&*#*')%+&*#()+%"(!)!!!)'+!$("('"&)+*+!(&*!$#!##!%#$("$)*+"($%##'$(!++('#(!##+"#%&"$"*$'%"!%*%%#!($(&%%($'"')'*)!$'()!#&"%)()*%+%!%&!'#&+#*++!+)$('!)($+&
@r3793
ATAGACAATAACTACCGATGTCATATACCCATNCTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGAT
+
=9F(06'4B7E#-+EB%G>A168,;.E-6#2<7B21-@<D081?9G?D1.@&&.$C!&,0#)>97D>*&@:7
@r3794
ACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAA
+
4C'C)4:#>"&/?$3E--H$E59@@A+.B$"2/4GA5'<@H+C<'1=*:G1A99<#.E8#,99%#!(),3G
@r3795
GCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGT
+
4,$.+?:HA14G&G(;<F:03@C@9;54D$=:1&()E1F,:C2'=@%:+B,6<0A,54
@r3796
TGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCA
+
G5%<*@+1),?D3'+2>*#15A/'70>10.(0"*8DC*-"8DA1.7A?C+HD?:3!9F7<4!1!
@r3797
TATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTAGGCAAAACGTGCAGAAGATATAGCTTCAC
+
C!0#?57D=?829FB!<B:6FAC5(0G0?D061FD4;*0AGF:8+8F;&HA6,B#ED0*B$.='G/&@,F=1!!?4&D'2*AE9?*5
@r3798
TATCCCAGAACTTCACAACTTCCCTGACAAACCGATATNTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTNGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGC
+
.,5B@''*0A4FG8>17A@A4&?8)H#+>09.88AA$9*A63B,-7C.>@"F/<A@8--&-?-91"7A,:%H%3H/:@@5'.?C-*1<(A>4%5AF;#776)%"+,)%89@;*A782-9D1<.-@4<4EC"H6119<'59&%!.):25>%<0&@@%..>-F*DC/&G"?CG#
@r3799
CTGTAGCAGTAATATCCATTGTTTCTTNTATATAGGTTAGGGGGTAAATCCCGNCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCNCTTCAAAAGGCCACCTGTTACTGGTCGATTTGAGTCAACNTTTACCGCTGATTCGTGGAACTGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGTTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCG
+
"D8<F0*739&=)C;H9".%>&HA::;$6B!<4913.84A4H>?&E36!4D+#B6F87!?074'BE%&7;DB"?*-"B!.%A'*(8=CD&>D28)&4,0+*4-%-96"8,=)>A<9+*B+>/7(>(&2*?:A#&:8=+(3-66.&B2C01-=0?1';@,'9@/;>'H166.3C2E@58%>%04&0F0?0'%86;.*H$7!%>D'<67A>H+80')E;+?0A&148+!18)E;<?4(8!882,#9;,&!;!3AF"-!<0076;8=F19+?.5A-.8'1D
@r3800
TATGCGAGGCTGGACAATCAAGGGGAACCCCGCCAGCGGTCGTGCTGTATTGTCTCANGAACAGGATGGAA
+
,<3E1G8472-$?FA%:8:!>>(1CE$<6>9>09E!D$)C7*CG;,H#-*('*&CB8&H#D'%,*-",6F%
@r3801
TTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCTTGTAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATNACGTTCTGCGGTTAGTTANTATATTGTAAAGCTGAGTATTGGTTT
+
'@.CCAC3B'!?G37'F&(!-9@@;C%;3;%4D:)&E&&?9@FA,2F1>3-1E/#&D4=@*2H,.E0>7"*0:.#>*BG'$)E696*.%'%&*,+>3$AGE'G5<&)8B#E)81#C"H-<B?<A"C"9'#D%0&1C16AG35!H3=<G3"H02DB<EG2-/#@A-%EH@1D>1)+F/E91-"=):3$G)1$($%*&A-7!@;="A%1&B$$6H;3H;E%*.4#G)9%80&+-$@"'%:
@r3802
AGATCTCGGCGTATATCAAAGCGNGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTG
+
:#1,A20F2%308C6G96?-!10"B4=&76=(%':33H1H9A,;D)A#39#E=%4#$#0,<1++:B10<C:4E4
@r3803
CAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTC
+
C1?C4-$@"*".G7G98;8&E?./@6-A@9733B507B3)'9!CB?EHFF7G8$2)07+>
@r3804
CAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGG
+
/=,"-<BGD3A+4=EF400197C7@$,5-3"0468=:4"6-E&=2+=)5,:@H$<$9,+C?(07F-2F5%0HH(6EH?-3A+>!7B"=>-.
@r3805
GATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTNACGGAAGTTCATCTGCTTNATGG
+
*,,)8.(BG@CGGCFB#4D>:C!'!.:);630(%#A=(@4#5G+':+C&(6!0?!*'C*,+-@?-76)7((!)=BDFE+)
@r3806
CCTCATCANAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTT
+
&A4B4.<.!,<)!@7.E"7;A44-1CH299,6.,16B2D%=*3+?E(3(3"4A>@4E,E+.+F!"=!E)@))(3+DD@C+B;$"@7E47GH5!"808B7'*(=2F?G2FF@D??GA<GF=3*7@9C)5-,:6:H?6C#&0F1'-DBGDA:4!@@B$.<28$
@r3807
AGNGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTNAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATA
+
)!-9&#CD9-AC#?DC%#,@.'!D4:8>,E&9911H"F(A)934B9C07=;:@4F1H"1.H292.)6=(H3-F:!0?><D2D;%H3369/1/F5>9<.=0>11'H'=F0+)0'+FG*A!B#F&3!&D=:1C>-C50/F4'#@$%B)$5@*$F!>H7?($..<?G8F70&66F+3<!?)4
@r3808
GCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAA
+
9/0G)$-7&F$)=21=E3"E26.&3A$*80E;4#;%1FAC@G0D1FG>/=%,1(>3(2)H6>1>&!0;'?
@r3809
TTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCG
+
A>81'-4%7+0D1<E'*=&@C3$,(2+";607!9G.!(,<H6'"E;+F7D/,@;EG!(#A8/.H4CB:C>8/5:E,42,6D;GB5GB%0>>57'?0C=/F9/,=-H=$2-A,F.@;G
@r3810
CACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGT
+
2/FA?BF$D'FACE8<.3A!/66D>$?-#('<693FD8376'B3/.(F615,/B
@r3811
CTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTT
+
5D?;=0C$?=>&%$168:?=8=%4):@:;GGGEG(&*5E62A67/F<D:7:!,52:
@r3812
CTACCGCAAGCAGCTTGGCCTTAAAGANTTCTCTCCGAANAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGNCTGACAGCCTGATTGCAAAAT
+
&%+!#%$("+"&')"$&+%*(+(&&!()++')%"&('$)!!&$"#+%+$#+)()"()$(!#*)!+&"!'+(&)(**('!(#"#&+!*!#&$""#'!++''*"()'(('%%$!)*$'))*$#$$'%"%+*$!!%!!"*&%)("#*'$#(%)*($%!"'$"')&+""$++&"*((#*&&#)#+%&'$"+&&&$*$"+!()!("+$)(*#&(
@r3813
GCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCG
+
=8!=(=?8?@3.2*DC=.2;<$%-9A><1.1.0?$2(;G9E3;9%!?E#.79)(%;(/9>-:+EBD)1E8@-B%E?14=6!:H11470+52#0*H8!?D(EE81)'1:H6
@r3814
ACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGNACTCTGTGCNACCACGGACG
+
)068(C@*'-=*45912F:..#D9%H819'3+%1!A57GD,;,D#1A90.1E@6!+"F;.9?/=#/28#'912
@r3815
AAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACNGAATCCCCGATCATCTATCGCNACGAAAGTATGCGTANCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCNTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGG
+
F+>'",D5C,*::$3=;0&B-%/<,C$2&>&7%F,;/72#/*)$C(F?@E:H5EB$B,H(;>#43A=>)',C,<&6'#GE3.1@F7<<8%7:F:D$HD$:08B@$H.CEC7!#52E1.2%337:+H06>.&E=GA:0&A-&2.">$$+D@92%!!2@4:%19-!E-0>5:6774$.*<E*BEC-A$3C$>309D%="+1004&.'DE3"=9&?@90&9G&D6,.C8&+?16>>EE/H.%%'>H7?57*
@r3816
ATCNTCAAGNGCCAGNCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGCGCGGCAAA
+
*&*"$%*'#%($***!+*'*!'!%(!$&($&&*%!&"*"&+##&(+'&*!'*)!++))!(!!)""*
@r3817
TATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAA
+
3<=!$!F7<7FEDDB,7"67E"H3!B&;3@E'ABF(:*(.>$5A-,(!D=H=D1<*#/0A5/"$402:<,F=F.=#+&::!-*7$+C1$;HC3&9FE,(H/F5%;=FH+";C$,-
@r3818
TGTTACAATGTTTTATCTTACTGTCTTTNATGAGCATGGTGAAAAATGCGATNT
+
<:;.64(:':C.D>*6<*H*1%.0:B3H<;4:D56-.5E/?69A"6=/$)C@=1
@r3819
AAAGCAGTGTGGACTGGGCGTCAGGTACCCGTACTGTCACCGTGACCGAT
+
5'4-H,?@E442-#)GF-6B7(EHF&-,"*19@@;,!>-G%&@;-C0#9B
@r3820
AGAGCACATCCTGTNATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGNTTTTTNAAGTTNGCAGAATCGTATGTGTAGAAANTTAAACAAACCCTAAACAATGAGTTGAAACTTCATATTCTTAATATTTATTA
+
$?),*3E6/#(F81H1)@)",CE44-,7)66AGE,DA&0A%/H-:C'5+!;GF,,C!"=B(G082)$9/?;BE!D@+.('=>@0EF;9B?H$C0:0.!1A;HF%(%+E'(&=(C+1<##'6$5C4$F5.+5.3#95B"4B0HA"#E+1.F380FF,%9,
@r3821
AGTGAGCGTGGCGCTGTACCTATGATTGATCGTGGAGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCNGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAA
+
(!")+)')"!"$!$$(&%$%'!!&'*'#&*+&'#&)"$&)))(&'((&&("#'*$(!+!*(#%#)+%*('&!%&"#&(&#*)#!!$!&(")%*##('!$'$++))))'$&*$)"'"#&)'#**#&+"(("%!$")!((&"#*#")%#
@r3822
TTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATC
+
5EB)64@3H,G/43!4H@!B7CG07D@&$F=7/=E-5<'+-!?5#G3"+%;'?,?E2$4(./2FE$CC.,&&.-DF@BGEG*BDB<)/(>)''GG8B%/!/$C61;H7B6+4!D:1-$2:44(175!H2##+FC;!3C76
@r3823
ATCTGGANCTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCA
+
A$>-E@'8(A602<67?63/>G=6-F<-D196*0#=1@+F*#A$@/+@H,;:(E?-E7-H7.&86F/>A>F08D/;$7+18#")!3B=F"7BF/$77(3B;=@66!)61C8A6:3B0A??>9:);0?*;?2-7,/C:E3.8;211CG6A%8,C<1<&9D-96E!:+)6%F)/2B/5-1EE
@r3824
TAATNACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCA
+
(('&!+!'$$(%(!&#)()+!$'(!'*'$'"*$*!+'%%(+)
@r3825
NCTTGTTNANTNGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGANCGGAGTAATCAGTAAATAGCTCTCCG
+
!#$'&(%''"(#""++%)+($(!)"'#*'+$##$*+&%*+*%('('(()**+$+)"'+*)!'!+%!""''!!%)(#
@r3826
GATTGGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTT
+
<!*<6#=8&-6-H";89C4>385C6-66&$H)@#&$*.*8)&+434G46<HF1E#-H8F3/:8E@A!,0F-'CE@0,A$H?1H*H#?:5/-0$#02F13'
@r3827
GAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAA
+
G76!'?7CC5-6C<?FB9?29)7@+7323=!FE"!'0'::(>/
@r3828
NAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATT
+
!<-A==9!"H&H@G9'6&/C6@1?%/*#/92#11*2'%=>E+6#7F--4%<%)G+B>E(@E74/142+D+=%0*:B&G/8:<#9
@r3829
CTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTG
+
9021*;#<)>=87*02-D+304/AE%-;3?*%5=C/0985H%EF>-&+9
@r3830
GGGAACGTAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACNTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGNCCTGCCACCG
+
/@<%((G9'(-2,"!0&#/0-G2A5E%:0<)=B6F<(8*'),)!'35%:=%<'9F!<A:)%+(?1A8HE01$D;3@ABAA8G&3+96ECG?A%%/06F!==3:';4<"$H';$3C&D,>G/<')#@912EB805?G/0@*33H>$.4#E7B>"G!8,9<?=%G/#?<@8+6"&9B8*6)3(15*4+C0.E*E0*3(*C"@F?G0@4=H-#F'@A9#*9?0$':C>$B,#45E"7&33C,D=A#7&45/A1FA/7C3<5D#CHF2"-H8E">@62=8&%7GD+:$-?'9F1G-:5@,.#0$&F1(#F'E()&G39>+#D#90A$#$7-77>)-,A%9
@r3831
CAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTANGCANGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGA
+
9ADC*E<"2/7E.D20,)=!<B(912H;:7-7(191.2A:E?('5,D/%D53D785"E"9C-$F?;)*A0?5(#1E5?2A">*;*H+"!:G).'71700?,;,F:2!,-+!2<<**<%7E?*GB58C7!
@r3832
GCTGATTGCCGNTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTA
+
.11%(E)%F%90%BBD/=?33CE@=G3A6/="&7'*H?D"6,;=?$-B9'$%E?=)31'D9<E)-(D+<>"='4($B-"*6"=;39*2:*%@"*<BFB8
@r3833
CGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCA
+
4G6-?D:+3,>C<.!@*795'41$=6A*>!'=H+3<856E$.E"B17(@%E4>59.40>,%
@r3834
CTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAATGGTGACC
+
1&4'AA=C17>C&BBE'#-%G!@!)?<:)<$C:7&F9<E'24E)@3
@r3835
CAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCNCACCGTCGAACACTTTCCCGCAGNAACAGGCTCTGCGGGCC
+
C$1/9)9E5!98G;6F?(65>*2/@!A#&GB(G43>G,0DBA#1#/"*9;33"A41H"2@/(EBE91&=3&,>F=%-$*?)$6:A!D53#,$8G6BD;(:4G;6G/2+29"6,C)!A!<;<(>'D4&+B65F356
@r3836
AAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCC
+
*;.%B0'!3G-33<>4B!">6E1C&42/1F=A7+/"6#-@6HH3"DDD1'+?=(!@"::3;H/DD0.E@A;$C*-%BC"04&82856+-9A(6HCB.
@r3837
AGACCTGGGCAGACAGGACTGCGCGNGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGAAGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGNGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGANCAGCAGACTCAACAG
+
(;>$>&@-$*#8:#F4:G%<9E6@1@DA"7=025>37$$2738?A?1,?B<B5@).=%$83<$:4/B*D'$$F+D8###GG@.$="-+E2'C7$#"-F0G68&G1/5'8D/B)#%:(!,;H&E6362!+1:E+0>>:-'6E70FA6$/@$6?91+26(A#3G'>&)41??9FD-4B2G)2B)%/@+3/E>A3H)#."6,21752)7:-43'?+F=/8B6@E9#?1<A?AA=5C*"H6"AC@6,3/;+/;/:E%&1?D
@r3838
TCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTANCCCACCCAGCAAAATTCGGTTNTCTGGCT
+
7C&,"0F&':F8?C-7?9;,F&>"8=1/D-8!E9>C-,H&#5>&+9=->4$56*H:@B&7>BB.=3%D1(-<2G5<7%D!'12$(%6:6<,)995,,@1,=@><<7F@&66
@r3839
TNAAAATATCTCCGGCCTTATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGCTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTANATCCCTTTTAAATTTTGGCTTAATGACTATATCNAATGAGTCAAAAAGCTCCCCTTCANTATCTGTT
+
$+%'!)#!$'*!")*+#%+(#+#+'!)#!%%%'%#!#"!%)&)#&'##($**!'((#%*"%*$$*#*"#"&'+$&'%$+($&%'%"))+(#*+()!!&')'%(*$"#&")&*#$'$*$&"'((!&+)&(%(!*')*+!#)"%(!&)$%)$'''#)'"'&$#
@r3840
TCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGAT
+
'FHF;./.D>)<BE/!3E<A&'.HH,A>9>43B0".;C?3,(!;7)6"
@r3841
ANATTACGCTCGAAANNNNAGNTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAANTTAGAAAAGCTTTATGAAAATAATCTCCGANATAAAAA
+
)$")&#'#(*&&&"%')%!##%(+$"&#*'$*"*$#(#+(!+&)(+##"#$'$''(!$(%(#(!))(*%""*&!)&+$'&)(((+)#%&$!((+()"%#$*'&$%&#+&+(((#"$(&!(*(!+!(+$#")
@r3842
GCCGTATACGTTTGCCAGTGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGNGGACATGGTACGTTTACGGTGGGCTATNTNCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGNGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTG
+
1B->E'G-A=-.>/(?+>AG6@F>/3'=B2<+*,B??;#F;'G6=67<3?C>/7B@#HH"1B$>DF87(:-;.@H0"4H?E'7<<E)"EA/3,@E(E1$(G)5&9%#'<")9!0BCB?)"2?%0"+#->4''+)'>H52/F<D/>BA:"6-BF++/"C=3;:4C4B&+>H*8$G!C=89%$&D<ED*:7/!+)6'!6(4B05-8)96FEE36$GE$#1'>*9!80:#..F&+H(3FG.)*6B=:-<849.5(1016C;'.G(*$!F,;17?+!'%B'H7/*?@2*!497/-7C*H;H!)7=50G;8!7+C3>*8836'CCF%/:;;/A;B/1E2+7+*<0;)H4'2>C(74277>B"2)(&H0E9)@D..@!%?!A!3@?<86E45G;2D&7)..
@r3843
CAATGATCAAACAACTTGNATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCAT
+
5'A.FB;E=3-2(/-78!"3527*47*1)F4=56AAB"9$4&",340"'<B,D96/'4E3(ED.>%1*!?.H"6;8F-'
@r3844
GACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGNTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCANTCCGGCTGGTTG
+
+(!+)'#%+)+""')#)%"$'"%*#)&$"((!((+*("&$+!"(%%#*&'$$%&*("&'#)!%)*+%"!&(&+$'($!%%$&##"'+&'(*!+$$+&++&
@r3845
TGCCCTTTCACCACCGAGGTGCTGGCAGGCNTCACGGTCAT
+
5))'D0"$6'?>E'&C->7;:*>#::(9;1@+DBC66ED+0
@r3846
TTAGTCAGACTTGCAGAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATCATTACATGCCTTAGCTATAA
+
@10)(G+('&E=?B#?G+!.%EC;1,;D,3$*#(8>=<-H8&F$+.$341G79&DC2@:<>#BH;$:")DH/C$.@E%"6+?HE40&)4)3E6@*A6=>0FB%:HFA$+!&#1H2/?/7.F)66
@r3847
AAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATT
+
GD4$79?%"'8E@4G74E-E:!!C5E:#E5?0H=&4#G-;58;,)$ED$);+8?%,=0'$<G9::*0+5%%A*G=70D)")2,4?6E>=*3?F)(?
@r3848
GAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGNGAAGGTCACGAATGAACCAGGCAATAATGGCGCACATCGTTGCGNCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCAAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTC
+
+"D2809+95(?-(,<C?$C5HC:?F"6,9=?9F44!"!#3B(%$D&7<=G3)7$@("=89;?D%+46:A-6..;-:3+6.0%F1H$@+?3@,/'2-67/9:/?,-E7))/E2.5$1C?450#854/H4C5"=;@05%H!:<6"88,+#5+9##=;E95-?@"06<6E@=H.B2CH62-<5F(>G$248B1GD*5+8<.C+8D9$EC/).7&/A<@!%G@&B10.8H$'6"5%F+&4D!446.#?
@r3849
TGAAAGGGATGCGGCTAACGTATGAAATTCTTNGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCNAGGCTATTATACTCGTTCTTAACTCAACAGAAGATGCTTAGTGNATACANCCCCT
+
:%$A#F8'E1;"1B"FC&F>D)4B1G2"2@C6+H&1F68&9,@<;.)&3%B*;?@3:4FG=/$.)D;8<?F<G9$8<E8!,A.?:BF0'9E;-G$G>?(3$<<>5*"$?:G>5;$A#:$H"=$F72>(8:)A0&
@r3850
GTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTA
+
+#('##%)"*!"'($!"!&*!('(##&#!)!!+'!(!#&$"%+
@r3851
ACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATC
+
+5>:4-7=B<F+A<@2'5&?(F3;;/3B=;*G93<?..;-G,C/
@r3852
NCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGC
+
/CE0A*&/==.<:C)D1(<H.%*4,'G3C'6/?:+46@$*9'8BF
@r3853
AATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCNATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCC
+
=B>6=,3">'0./H/=F??#:=H(&)3GF@C@?"4>)%#<.G'&++H=HFH#9!F!(@&4!);4B:<&1@3$>*/F/)#8#353D1.&4>-#+'>G$"EA+2&B59-AH1C96*;1E2+E3%7%E6/+!#5?*H=-B;;84"+AGC3!"6H,FFF5*7,6!D)8H;C'@,:&=#!AD%<?'"2!8.%+,5B4!"#!33HD)4$7?5
@r3854
NGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAA
+
'9+H+A8%+=1*B1BCH41C2-0E.32AG9@.$+2%B>E'65*;7(@9==A;3GED%@0>&@A/"0(/A##+*,91'5<
@r3855
AGCGCGCNANNTGNGCANGTGATCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACNTCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTG
+
($''(&'!'!%!($''#*($!"))$%(%+#*+*!"'(")')'(!$#((*(*!"&)(!+$#(+*$%%++)!'#!$&#$&#+*'$('*'#*++*+++("**%)#!"$"&*$%&!'++)((+%!'!'#!&'')(&)($%$""#$'$($&$$+*"*!*&++$#)+*!**"&"##)!"(&%#!*%!)
@r3856
CTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAAC
+
@*7?C4?1A(A8A69=E3A(E83F!:%$?90=.B202G8<0E;2-F1BH%F
@r3857
CTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACNAATCCAGGCTACTGTGTTTNGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTNTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCANTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTNGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTAT
+
90&8!,'$#23!3':=6?/7&B$@&?$)9FE7.HB(G7-@6&A:H.A6H,2@?>'(B*:$7,"3?.8.+3%#-.C=91E<F74F*;342"C+C$0#+",/6:";1F&@-E)CE-F@@'3F5*(<:=-*"35<5=0#,D&/>()#@)56FH6=F-<##'/;->F'+@8-4/?&,/04@<'302G82F%-">C0?62@42/9G$#7$@##7G'B1<<?"B#4BG>A?2;)4?!1"+G1B,!?=<;!BC;%2>FE()7)E"-8%6%)E+0?A;.;.=1%;-D?")?(1DD9)2>"-?6@!G0=?0'7%0B;+;>(.2,EB%>,?;.8C+"*;$6>79.:3+.<&E/):,27/G16B0-?63@0BH3B$;$3'##$',.E'"*'067(?;$715A"%67%H>F#H"?):.&4?/,D:%..EE'%A.+691D)+A%0AF(C=<#78(55:/G;
@r3858
GGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAG
+
*(+&(#&!"(($*"*)$$(*&)'*!'$)'%&(+!$'%&+($!&%
@r3859
CTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGNCTTTNCCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTAATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGANGACAGCTA
+
3.(1818&:A>C"2,>!:H@*7;=6:=.B+5(,B;4D=:.68EA"&8?ABG)8,42A8G;.0.<!%==.31)H"1>$@9@-7=<D&/$59:#8=CBB(78#9,H$E9'7<760*)7C+9D><HC;3C$4GBG"0"=BCGE!<'**$7*:>;F)4C-B!*+G($<%2.,-*"7%2+C>"$+:,03F"$;>#!':920D<0="8$:!3@D)ED83@196F1/1
@r3860
GTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGG
+
="=911B%@B;)%$/B)@$+,=3:1&41B.+57,##.7?7=>4$0:DG,-D4!.C1H011*83BECB.>"#A
@r3861
GCCCCTGCCCGGTCGCATTCCAGTCTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGAC
+
*1($,)2)+F&);7=B!5BAC=1!+6=83;<A7B8F;+'7F)=!605@HF:+./".2=BB#2G)(H
@r3862
ACCGTGCTGCGATCTNCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCNTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTNACCTAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAG
+
69/:F'8C<,@!@E"092#0,D@@=EA%H;.'5CA@>=':);)/G*CC9.:64%&;66'G$$16#>B?G/0&(9!F=334%D:6&+05E'H*?H>3&54=*'!6@%5*/7?))D>7)0G:=8'%$-!C=GG&E-':77BF(6(&4B"7+,G?D
@r3863
TGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTANATCGACATAAAAAAATCCCGTAAAAAAAGCCG
+
/#"6D3C7=A'..E!%9DH@4B&3+3;?/A."EA*GC&/C&822*34D36'7B?G:40H6'D98@:>4
@r3864
ATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTC
+
:%299/G!#)6:H="">@B4?!714<;1699,&,06#5(<=3,#@G."GE',G64A.G?H<8"B&5$H)25$"H!4B8#<GD(8!#.,'4)F,A)B<-+/1A-".'-01E03#A8688)<2;!)02;H.FH93/6B>+/A5)(6FCF3"2)*9#%'*$@
@r3865
CTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCC
+
)"+*'$%!+'+%'+&+&%(+)'#"#$%$)#&")&&))%%"&!"*!$#'+!""%(%"!+$%(+*(')!&(*&'!
@r3866
AGTGAAATATGACACGCCGATCACCCGCNCCATTAGGTCTGCAAACNTCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCC
+
;!A7)4<E'A1#<2:10<BG3;83();:G:+=@&/B+)?@C2$23BDA//3#><.@/G+,(#2$>H6:D;EF2D(.3-<(3A,ED2,-(;,0(;#C;",)#A1C-$9455%B98.4)+G'F?C%D(GC7;?4.HA@(*)H&H$<%#<H%;F00F:>@"=2GB=$+**20!0@,C(E)?3!7;?07)*$,.2@>0&5D6,!/+G=3<.2-4">E,CF-H;3:12H:>/F"!G1*BDD;+;/!)'
@r3867
TCCTCGCANAACNANNAATANNGAGCGCTNGTCANTTCTGCGCAGCAGTGCTCACACACTTGAACTTCCAGCA
+
(&()(*%'*%%'"(%($$)''#(""'$(&$$*%(#+#$#$!&""#!)%#"++!))*(!%($(%((%"**&%$)
@r3868
NTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCNGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGNACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTATGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGA
+
)B9F'5,1/7B344*1:%+5C"H:6.+%,1'-9?0,C;3-H9$A:C66/D51=.=,HB5/(:"1.$+,#-+;;:(EH=<(:*5%$4+5%(%A353,A,&D%<D%),H*E!B)'F*,&*$B2@?H+.E=0HE5$$$A3,DCE@%'+9:@7=(<?GG+;296$$90>9,*-C?%=4>5.F!%$<9-D)3E!!($4H&6!":%-7%G=$?-;")C10?@?=/C8,FD):H<%05D4>?:3>8.#"$0)H1#2A9,HB16$0@A'D9.=-
@r3869
GGACGGATAATATTTATTGCTTCTCTTGACCGTAGNANTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCANCGAGTAAGNCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGNANCTCTGGTTNATCGAATAAAACTAATGACTTTTCGC
+
()+#&$&)%(&&+*$(*'*#$$!$#('"((%"$##*(!")!%$#%)!%$&"%"!!"$*"+*!%!+%$''%$%$+%&&#'$*'$%!&+$#!))(+&*&%&%#"&!#)%!%!%$"$*'&&*#)"))&!(!&$#)')*)!$#)&#(#"$+#%)&'"*%++$#))&(*!#$&$%(("('!")%&""&))#%#%(%"$*(+)+"+'"'")$#)('"
@r3870
TTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAG
+
=*57A=%*!<:1+79?7@F!4.@#-)*+F:>;0;'B1F:B71@?=F>8E
@r3871
CTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCA
+
"-82C=D9"5D"A7#=!;'9-A@<"5,;F/G-$36+0G4;H
@r3872
GCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACTGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTG
+
H)#'#=,!,5;3F(1=.;27>F267-1GH?E%C6!4CH6>C3)D+8)1B/HDF;H'=D9F.:)B<?;>+>)C?!?.#",2-A)*702;-.("?97;!/':*B?7;5?A365'+0)C.;3F%8E65)B2/"$816EE.)@*A7+?4;D8!3-
@r3873
GAACCATGNGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAA
+
4H,B+/+'<B'$4(ABF%65$?.D/6>:61"32B/'50&.==':H&"@=6!%)9%(>((,?%+-93?-7HC--9;%E9.>D.;*A4BF3)34+'32#3311C(-$.<5<0D)253#,3;,$@;;@A6GA;5%2$C$@'5@<
@r3874
GGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGT
+
93,0%8%6(<!==)AC8*("G74?%#3G&)$D!11G6=-6+CC5>
@r3875
TTCTTTATTCATTTTGTCGCTNCATGCGCTGGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCG
+
++$'*)(%$#*)!&)**)($$%#++($)(#"++#$&(*$"&*($$!*$(+#&!!""!))'"(""+$++$%"'#$+&)#&$'!&))!+%"(*%*+*'#'%+&&!"("(')&'#%
@r3876
GTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACC
+
@79!(8.('(H-+A@2?:,/74&A!FB7,@/+#>B;&FH&8"$9"!-F%G,1)!%35@%%F%$4%?H2.-03::.80C&@",7#-F,)?/H6-!$"?:H"@/$-.&?@$B%8D'$#DFC6GGE-61!%*(<<)@2&FG'9)$8
@r3877
GTAAGCCGATAGATAGCCACGGACTTCGTAGCCATNTTTCATCAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGNTGTGGGGAAGTCGTGAAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTATTACTGGTTATGCAGGT
+
$'-88A>@%87))>7$356$*%>C2B99GF(;6C6?G005@?"16!%2>)&3B>7#&(B!@6H4</")H(7&5A34#:@9)A(4*#0,1='/)&?)(%+0?F.DBF<A,:HD<=-@'1-/6>-!'A2'%8(=9%4!28$)"9#11?C/;6'..E2#6@&.9DC=&!"(/:2/=6@%*:5=#0F46;@&8@/
@r3878
GCACGCTCAATCTGACAGGTGCATCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTC
+
G.)5+,'+79%.="'B5E8D76(7>&>14:41B?H1>$?@++/$('GF;5,9=3%4FB?/#0(2>'-1=2!AHA
@r3879
CGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGNTTTCACGAAGGTCANGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCNGTTTGGGTTGTGCTGTT
+
<07CB.(C#)",-@D=+18>(,5E+C-4DD-;,AGE?&(+!#G<7C5"A$8$6?>3+>6GHF%$,0"5&9)2)>,:(7>"D#<E4E*?"&EBAC;',7A<@<=5D!,>D6-GEH52EH0*8D$//-*#*24
@r3880
GCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTT
+
.2*",!7);%CB&GBE6F@25!@:3'BEB5(3>439.#$:#-+@,*5"4(D3H53$<'>1F-14=B(F4F0A=FG4)4+B&>-08H?2H$/G9="C
@r3881
AGAATACGCCCGNGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGAC
+
8C;"?="**A?/9/>CBD431GH'=4%'*8.A+C:2%28@,%GF"A=<F!<+AA3+H*C!6-&FGADFH*HE7@4E(
@r3882
AAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCNTCCCACCAACGGGAGAGAAGCTGGT
+
C@;D.("=%F22;D6)/1+3>?B?(B'5HG!@2#-)4=1<!EG<?)%-/3.F1)%4:.F39HG='744<3618&B9$,;(!89>$&B/F*15B;C()H!$89-?>%;/=9A.8D
@r3883
NTCAAAATGGAGAGTTTTATGACTAAAAAACCATGTGAAAGAAGACTTAAAGATTTATCGCACTTNCTCAAATGATGCAT
+
%D8)/6;H-9))DHD5-.)<<2B$+)G:,4)##.=#-%C)>ADF1*C!<!1?D'%F;-==A#G,GF?DC>9#>%=6(G1"
@r3884
GTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGC
+
F='E3606#-@=./;-D33+')B7@/!&B#DB%8"-H6A(HF9-3
@r3885
TGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCAC
+
H48G<31(&E/H2D)0C?>;0"5&!37E:+:,.$E+%1!9!9G>)>6G%7!.,6'#6F'G96<D"%;7H"@3>=
@r3886
CTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGAT
+
"=DF8+G??C*@>.+3G2$+>(0+3'%=0@H4A&.)H,7#.E8&2136<CD?7B'67GG
@r3887
TCCAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCGCCAAACCGCAAGAA
+
1A3(1:!G1B&,2,84;GF=%H"E7)G':=.;H!3GE&>?<,@8/=:;5%2B<89595@9/;F/"9(5'0EC$#%G,-A55/)F4-6EFG42#>5!#=0=+>.9H;D&3:!90C;E744$/<%EE/?8E>5A2+,,3728C,4"E&B2,"54<)!&9!7,65E#%B2!%+3&&&4F5
@r3888
CGCCCGGCGGGATGGTGGCGGGGTCATTTGACTGCGCTGA
+
7HB06-#2AA**79H<A2.&+8!8>;A1;-1CH>-=D8/F
@r3889
ACCGGGATGGCGGAAGATATGCAAAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGC
+
.0,B.8..G1=<H"3%5@B0-";57@?7-G</)6#2?6F6:7'))/+2CCDDG;301F:;?!"*5,0F;$A"H*BA0..-$3"F&,/((.2.B=F;#61*$CA$<"&;(38<B%<"7E"H9
@r3890
ACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACAT
+
1?,3&B6D5%@?0'.1@8-E&,=/?(5904:!F(=$.<,*C0-1,@1,)?2-7D#$2(=1?*1:.6%.3A.C+-D>-6@51,G>'#=:?,(6/%+.5:1395!!@H"0>DB#97<$%F.*6C/?$2+1E)4;1E)F
@r3891
TAAGACAGCGNNCCGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCTATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCAT
+
#!%#*%#*(!#")"'%++#'+"''#%#%*&+'&#*"$%&'##&#&((!")&)*")'(#&+*#!%%#*!)&*!)*'+*"&"%(+'"%$+(&"%&'+$#"*#*"$!!*$$$$(%(
@r3892
GAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGA
+
8-77*%!<4&)14.99-E>93FEC=@)!##3;G(*"*'B6B4C3,8/:-2#4G/&"+55$7+9%?*+()##DG*>>-
@r3893
TNTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTG
+
*"*C02C4-'+9B+'(==5H8-&1=")##>1<*",E/=>,<,25/@HF2>4(<42,1*-0"9.5?0$:+D*5>.7E9&E%+3=07=9;B1)3(?G!)G,'<=:,;-;AC<#8D(?@4&373
@r3894
GNCGCATATATTCCGCNTCATACCGGTCTGCCTGCAAACAGTACCGAGATTGCACCGCCAGATA
+
9D67&506:?15,8HHF'$-8&A/";3(7BG3E&>3'(2$A4/2/=+,-F=GH!%0#7(=(,<G
@r3895
GATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATT
+
@:+7#56+=%*61D;>1@"%.7/%DE!B+EH;)%G$01.A@<F,H.B<HDH+F4>7!63='/!F<&68-;E9663;7!*A:
@r3896
AAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATG
+
2?HE#2)BE01?4A#8?!$B=C$(/$H$(,2@-2%;H!CB9=EH1).9<?,#=%C;7FG",C3$.!<<58$"(*&7F,:6+;G(1&%=*3!)D
@r3897
TGCATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCNGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTT
+
'#!+$++((*&!$((*%$"*$+*'()""%+#)**%$%")!)"+"#'!*)$(%'*$'*'%&$*%"*!+'*!)"%!%)%"+*'**%$**&#+++&#$&&#"(!($#"$)##+'##!'%*))&'+%%
@r3898
GCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAA
+
G.7(4;?,9G'/67:>A%76!E)!?<E?:,-H66-F77#%G=
@r3899
CACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGNTGCCGGTCATACCACCGGCCCCAATGGCTGCCCC
+
(B;@;?,'%%+':##/50<!&%<4E7(4<)>.9,BF@!23:A'?HAF20>"/685>06DE/635=@->/*:#8
@r3900
CGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCA
+
(4*<7/18D197:;(04;B#!A?E;HDG2%8H#0/H.0$8$ECB0-A!0G!6&6
@r3901
TAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGAC
+
(2=H0B%74H;;*+5)*A#C5$,CAE1E/2D@F)F1:D0@7-GC=6)B
@r3902
AAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACNGAGG
+
%18=$>6$C6+.H=C:C3A=$+0<#-"'B&4:$13825/@AC
@r3903
TTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCNTTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCT
+
.3!&+F2<H+)?$+)*.9/"DG6=@8HB-62C0-59+%*;@"4>'>7'EG<"!'C$B;,>!8F?F6'<'20#&C<+F+%3)8/+706@$C.D%9@F*&9&?@<E>>B8:$$D:4;<@)15)>:0B&?+$06$,-86G;<</.2"?$'&92%:C94'>B9H???>=$"/H,D"93$FA9$14(-'A;.F)EC%FFA?3!0@5D;@)C'G0-F:@7FFF6:&B:2?2(AF=&D-D5C7H
@r3904
AAAANATCCCGAAACCGTTATGCAGGNTCTAACTATTACCTGCGAACTGTATCGGGATTGCATTTTGCAGACCTCTNTGCCTGCGATGGTTGGAGTTCCAGACGATACGTTGAAGTGACCAACTAGGCGGACTCGGTAGTAAGCGCCGNCTCTTTTCATCTCNCTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCCATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGC
+
:=%*G-HG-!#!95*F,2<9"@A";87*+&8(1D,4A3FH?28"6=/H@&+G9D#6+/&;0E75DB2,)2HD96&)&<@7-C&?E.#<6,-!))@@'#;'9D$?<$G2-#@%''"?4C<D;$:,A)?-,HAB9/+-&,/@E5E#B&%$:3$!-HF@C$=@92G69<@:'.8G*?:18/,D+"HA*GH<F1+A9.,(5"(*B*%(9<1."<:0$*,9G3G$>F:E524,)@A7-E<2%CD9<B)<#*'C+@AD$+464
@r3905
AAACACAACATATGCAGTCACTATGAATCAACNACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTC
+
$+&%!"+"!%$!%%(%(*+"%"+'%+()+'&"!!%'!#$"$&#*$*)&!%("!($%"*+$+*!'(&"$"#(&+#'!$&!)"&##))""
@r3906
GGCTCCTTTTTTATTATTCGCATTNACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGC
+
),@DCC3=<40AG!5@1A!05@>/=+7B./40E6E9.<62&&6-5A&;=";E*76,(1A1*6>G*G/)?BFG.5"B@3>"2>@79!C)5>*0=D57E0!D/;-F#C:/3'0+2%
@r3907
TCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGT
+
9@3"A#<%3-$H&0")>/5@"$)A(,;HD"<*%$,*?"7'C'A2E2'(E$89>F2,B
@r3908
CCGGCTGGAGTGANTGGGNAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCTCGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGT
+
D"1D4&H';C//?33.*3)580@9'CG&&(5DB,##(.C8'=9+G"$4#:9?-;>3,G5H-;>.!:=BEC(/=)CH/)*08$F,)>/9.";$(4%<%.4)=2?22'4).3@0'78&.:=41,;39.H5G>%/DE*+DGCF-!9
@r3909
TTTGTATTTGGGGAGCAATGGCGATGACGNATCCTCACGATAATATGCGGGTANGCGCAATCACTTTCGTCTACTCCGTTACAAACCGAGGCTGGGNA
+
('+"+*%%%&*)%#%%*&($(*(%+&$$'&"'!#(#&$#%"&)&$#+*')'&+!!&&+)!#"("'%#(!##&+"*+"'&%'%#!%*%$)&*)*''&#)
@r3910
TGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAA
+
D?0%$7;6D2G>CG23.&2:;H/6.%&*3+>&G0.,B9?76/'D>F?F$4+6A2GB4/4%F4B!!!+-.AA"A#
@r3911
CGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCNCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCGTTTTT
+
?H>0HGH:;*59"'$*'FF'&AD76.-4=!<$4.11$'E<:!=E45E@F5E71%&G5527D*!3<B-2BB,+'!-%9;2A'&/?E'>*:<@"
@r3912
GTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCC
+
@3*%E3E?$C;BG3A>8GF(4D&<#6#'33++6*1>CEF@*9-A,%-!/>*C)21=&<E+.9)@/B90?*GH*-22>DH615+1'+HA7A$20D</HF-)F79?-(-8:.;'>#A&?*"B(&G0'2=6GA-.?0F0%11;+#4,;BA!;4F?<<FCCE%97:!DE:C>3"/8B.5'&
@r3913
GCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAG
+
3!H4*>=;-/3D"?6-=B-,4-G0D5:.3+2)#B9#"2B2(0(9B1FC:"5=69*9.H1E+0A)(B80=+)<?C>$AH21.@D
@r3914
NGNCTGTTGGCGNTNNGNCNNCNTNNTNAGAAGTCAATNCNNTNNNGGCCNAGTTNANNNNNNCNNNNGNCCTNCTANNCCANCANGNGGNNNGTCCGGCNCAGCCNNNGCTGNCCCTCTNCGNNGCGGNTN
+
$#!!!$$!!$""""##!""#"$!$##"!$!$"#"$#$$#!#"""""$!$#"$!#""##"!#"#""#!!!"#"$!!!##!$$#$#"!$###"!!$!!""$""!#"!!#$#$"##$#"#"!"!"!#$"#$""!!
@r3915
ANAGTTNGNTNGACTTCGGNNNANAGAACCTTTTCTGCGNCGCCACAAATTTTGGCNGCATCGACANTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTCTTGAACAGTAAACGTCTGTTGAGNACATCC
+
'"'*&'"%$"")!)'$'!#"!%#!)%*($+%#'#($%*'#&*(+*+!+**$+'+#)(%#%$(!(+)(%#%#%'#("*#%$"&$'*))!(("((*"!%$$!*)*'##'$!!&#&()%"&(&(#)#*&)$)!(%&$*((!(!%*(%$"+*'*&)"(!('((*$(#*&(#(#)(#!
@r3916
AATAAATAGNTACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGTCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGNCCACCATGAAGGTGACGCTCTTANAAATTAAGC
+
<G,D3=%><#'".7HD=C$(D<<6.3<4#<+9"/+4H(3.$('BD3*,;=!A$D93*G@"=>8A94(16+#(71?981<":@4"#C87,1>G.)B#45)0@6%!2>)>>GH=H)H!'.+CF6<"DA2)"34HA)AE82/6+$F=+!'C=E0%%2(*#@H)3"!B4";!02.%H054@3%/-BE$3F.5CHF5&CF&0>B8?-2)$A<8*4D4H"71H93-
@r3917
GGCTCGCNTACNACTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAA
+
%''$!$$#$$%'!)+)'")$#"$('##"%+'+)+)"!&)$%+$)'+('#*!%*&%%))*$'%**'(''$"#!')*()$$""&+*!
@r3918
TGCTGCACCGCTGGCGGCGTGANACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTG
+
>6,&73=?(&07A.8#1H64A&9#.64GBF+GCD+6@3*95*.<@7>5E.B=-:$H-H%
@r3919
GCCGACCGGCGGCTGCAGGTGTAGAGTGATTTGCCGTGGTGGCTGGTCTGC
+
CCB@/><'%:(,)6>!F17'9(D7(C6=%3,FABF@DC*4/A2)%C=?)?'
@r3920
NCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCNTCTGCTCACGGTCAAAG
+
$$'6/HB@>790=1???'#4,3<<D(1"G01CE$0;G:G-3330F26+BHG"5,@,@&>23"1.'7?*<(:!2A)69
@r3921
CGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCA
+
")70CF"D=;#;E"2D"F1H1+!C19(8=B):$(:E2%10,+7?-5*0=5?2&60=+;
@r3922
GAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGATC
+
D-E":'H@5>="=:'B06%E'4$5/$>#9*$(.D>B)+H;*A9,A;::*:=
@r3923
CATGAACGGCATCNCCGTGCTGCCGGTGTCCGGCACGCTGGT
+
@-)53+27=!A+!972;H#3/.&!0*8=DBH6"!;#G!>CH#
@r3924
TCACNNCATCGNGATGACNNAGNCNNGGAGTTGGACAAAATTGATATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTNCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCAC
+
&!')&"!$&%%('$)'#&!#&%(*!&(&&+"&&")!#(&+%*+()'%$$$)$$%(+$!'&"'+'#&)+('%*&%(!&")!&($!+'#&&*$+%&"+(*%+&##'*%$*)"#%*#!%+++++(#&!$(()')(#+&((!+'%+%)"'!#'""!**+$)*+#")++&$"&"""#!$)$+&#"*)"&!($!('!+')+%%")*&!+$$$")#+!"&$)!%"*'%%"$&)(+'!&!!)()!%#((&+
@r3925
ATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTGTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTTAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATAT
+
+%)+"(&%$+*!*+&)!('"$'+)#%%+""(!'*"'!)"+%(%*(!&%)!*&+$)#(++*$()**$"*!''&""$'%))''#**%**%))'$%%$*)"''*'%($(''%)(*%%$+$(&+$+"'%&%'%$)(+%)%(#*'%$$&+$$!+(#!#)#%)#'++*$!)*%')##'%$+"!!"&'!%'$%'&+'+$%+*%(+#&%$##%+#&#+%%*"$$&%*$#+$)#&!)%(!%+''*&'%&*("*!#*%'!($##($)$++'"!&*)"(#))*($!(##"#"+*"$&$*&('!)'&)%
@r3926
NNCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCC
+
##<6;;/1,7,01#$04H",HD32+@G>3<:8>B*8!A)<<"+D@.!#5&(-,A?!C9%$3F&.5;4&B3;4FG2BG7?GC,'"C4,$07$0..)'-A,FG@!';9&&>:H6?30/.?/G*916?$C*9#7.$=);.
@r3927
CNCANGTNGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCAGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTAATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGA
+
)"%!"'&%'$$+!$%!*)%($'"%''#*"(&!"&$*)#(+)!$&'+!&!!#*+&&%&(*#*!!!#)*%$(%!+#$!(+%"'!!#%&#+(!%#*#*"+($")"'*!%&+*("!)!*&+#+&(("$$((&+&$*)+)()$("&%$&)"#)+%$'!$"+!#!"'$')'+++%(+#&$!&#*++%+&'+"!'#&"*&$")%++&!&%'+)+##"""&#'*%%#(
@r3928
NNGTGGTGAAAATCCCGATGGCGGTGCCGCTGANCACGGCGTTTAAACAAAATATTGAGCGGATAAGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGT
+
""+!&#)**)"*%!+%&$#$($#&"#)'$'#"'$"$'$"$+#"*!")$*'&)!(!$%%")*'!('$(!''+*&##"#%!!!)&!%)$'+++$$!&**+'$+"*"$("!+(#'**#$"#'+#(''
@r3929
CGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGG
+
*74DE7H-B"E1G$HE4%DGG@-0;?CA+!#.;<<)-$/;,8E@@E=D+A$%C""$(9#.!)"#>()6>3871<'060*63%9A1.>8GDG859<2!2E
@r3930
GCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACT
+
("<?1D>?C536$A,42;G3#6'-B=6@-;=4H>$@7!7:+--&:G&B%2AA9,91*0.(8?&80-1'D;;.,$1:A")H@B:0E#=$F</3)G,E@6(D61,86*;(.?;>6->%
@r3931
CCNGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGA
+
*"'"+*&#)))!&)*+&*++#%'$)#(!&$)("#!&%!+$%"%!'(*)!!'!(+'#%$*))%)!#!++!%'"#&+')!*++#")!(&%)(&$!
@r3932
GATTGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCATGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGG
+
8+2AF9G98/=H%H,,10GFG-/>?,9"!21.).2D0A)1*&F<%+G.E4(!<A16G3C)DD"4&%17<-A4/2F-5'>'0D1'.%(&)0A7%)+-%+)8B6@EB-.GG3-"G35&F)&"2(38=2:F1!.%#43)5(C7!=$@BG$1.)*H(A9E*D#D7%C)7#4(&?=;(G@F(F)CC!0D<(464D+,D1.G31,2B49HE:,HB
@r3933
TGNAACNTTCGAGNAGCATCGTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGNTTAAGCCTGAAGAAATGTT
+
$&!&&#!&&))*!#+%!+#**%''!$&)!#)&$&%'*$%"'*!"$(%%#$"!)!)&)(#**'*#+'%)$&$%%'&''($$&"+'%)&*$&&*)&++!'*#%*)!#'&"($%"#+%!%%(%"%&')+"!!#$$$#&#)'+'#&"+%'))(!#&+&"("
@r3934
GCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGG
+
<'1/H7(7(5$D6#)2=4?B88:G$89$%'A"E4@!-D$BAD
@r3935
ACACCAAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACA
+
=&11'.B;:0:@%-92B>@G9+1091(1C=!7A=C#C("390?!))7G
@r3936
TAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCNTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAANCAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTT
+
7>'%&%!-F<''G/+'F8;*CA-&9H,@10G<@C'$"=4&>FA(G7@-'7(3<A#&HC4/:<'AE:1D$75'475=09FED9E0C24)?A2+7;107"A:5&&B+>9$&>2/<*+2EB&&;>/%."C$$%+>=""*F0.1$09G&82?@0-(=@?=C7.2+!#:F>+4=,("7)(&5)AA+
@r3937
CACTNGTGGNNCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAANGTTACGTATCAGGANCGCCTGAACGCGC
+
*%&)))%*(!"+')!!*!$"*#+#'%'+!(##(!!"#'&$#+#+(%('"('+'"!'*#"#("*''$&""%*!)*&%(")#"+#*'$'"$)$(#
@r3938
CATAGTTAATCCGGGAATACAATGACGATTCATCGAACCTGACATACATTAATAAATATTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTNTGCGAACTTNANAAAGCATCGGGAATAACACCATGACAAAAATNCTACTCGCTACTGCGCTGGCCCTGCTTATAACAGGATGTGCTCAACAGA
+
,!82(ED=:<,+$."(,2A=B11H,(@':%<05+4<79<4'&90)2/29+BF<:02///+71/'+!(B99+*G+#.).=-%D>15H/E"7-4A78B-22C#,7"':6/@%E'+#F.BD(2C2,?8!,B3;A<:3(098E$<6=:(-'@=--/8',%:&4'!(HE$E&.@2*-$28@/A.C&&5$>3DB@9H'D?6=,B2.2)#A11)7%3<"/
@r3939
ATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGT
+
B/!@*9/4D?1.#824BF2CA%)D)1?3*E=+%2BG<3F/=G#%2+<-
@r3940
TACAGAAAANATAACGTTCNCCACCGACCTCTGTCAGNTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGGATCAGTTCACCACCTGTTCAAACG
+
+G"(6'&?@2'.&.3H&55F$84$/F2/D!/@GEH"1B!>>$.=-:B/-5498*'H>")-6"?"=@5EA><$."4HFD8%C584C9GF)887!886+B6-$D)!GH37&!;F/918(0F('G7)CH6*4C>6FF##;!50
@r3941
ACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCC
+
-=BD:E,)@==D6<@+*#>@DB@?E%E22$'6&2?'7!68
@r3942
TTACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCGTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATT
+
#62-G&9>:D#,G/6,:"(*/;$6D#D+90A"+9%-!"0AD%AEED+@!$F+DBF9:!><8AB;0A:2;614"97B&#@#"<.:/9/%/'*G0.AH<%>H&
@r3943
NATAACCGCCCAACTGCTGGCGNCAAATGAGCAGAAATTTAAGTNTGATCCGCTGTTTCTGCNTCTCTTTTTCCG
+
#(%()+&%''+!'$'(++#!#"$%""$()$+*(#%#&!!++*$+!!*'%(%&$(!#+%%($&#(*%)"++&'''%
@r3944
GACGAACCTCTGTAACACACTCAGACCNCGCTGGTGCCCAGCGCC
+
62!"0*1%<!D(B8&EH=2+,+BFE.7DA46"F".61=B1:)D@;
@r3945
CACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTNACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCNCCACTCATAA
+
-!8DF'+6HB7!F&%"A<;*8A*D)DBB6<.&!@/5+(<+G#B(010B54G#8=/2F3G:#%?1*F7H(F-8AA3DH3#:9@,$,A%(=D,!E"9%A0%+.59CDG58-6HD!(E>.@8;D>B/+1#5BE=*=:G'6C7;>.=<(#G4C950;DE*>.=@+:;'%G36
@r3946
ACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGGA
+
D:$,"($),4F4?D?-;,>%4%1/&@-/;$>C=*5/=H4"?C!8!5#8$$'A25F'>$,<F-,'-7#F/=.*G%#03FD,
@r3947
GGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTNTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAANG
+
H@<91G-*:>)20/F)23&?)6D0=2>*<DB4#*B!(26&E!<+*4++,!<7A=,.%"@G;G$5-*+B-F3#<0#7'98>0,@BG%%F02
@r3948
GCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTC
+
C.74:..5?0E@@=?'<2;6#;C/5935:%C-)9D38%&&"(11)#,@@+#1;6A9&%/1+88258?78'/:@<1.F%A)
@r3949
ACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGT
+
5)-?/=>)824:$)2)G%>"8G/3-3(>03A&C4?/4">5*@;72.;
@r3950
GCCTCGTTGATTCACGTTTTTGAACCCGCGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAA
+
H7-6GA;9;D(7@DH&:<1-GA!+D&B/78,@H2)A5<02%,2H&G%3!,8!&;#>%=#B,*,H2"!2<A3@F1'(EG6=.,(>0<;;))C$6>%DD.1.2:?;@<B
@r3951
GNGCTGGNNTACTGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCC
+
!!#&#$)"&)#%$&++"%)&!(""'!*&$*!+)%#"*+##$+(!"*$#%'%*%$(!'"$+&'()&&(&$+$"'+!(!)+%)(*)+!((*)#
@r3952
CGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATNACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCNGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCA
+
=E*'@1$G&!/D@5?-C27/B&C%$*($,,2':41.!6&;-))/F4-E=.:+#?6=8?><61+C;?&<!A0;"6GE14=2:4H&600*F"$6;60:8"3;-(?->3$6-1FHC1=G7&<HC&GH@5;<@=A=(@'B<:7/D0)=8A$GHE@(D/*831107%4C$:EF&9,D+6)",5G++G-@FF>7=?94D(09F:+<2B6?;$#G6"5,0&?,6-%&!63=&>;<7CE<=&%A1(HF)>5#4>-/=%;'EB/$'
@r3953
GCATNCCTTTCGGCATACCATTTTATNACGGCGGCAGAGTCATAAAGCACCTTATTACCCTTGNCACCGCCTCGCAGAACGGGCA
+
''#*(&&$'+'*"$###%(*!!"!"!"#"&)'))+&'#%%!*$('&)'$!*#*)!)"&"%!#'+!(")*)"+*)#(*$!%)+*))
@r3954
GGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACNGTCAGCCTGTAGTTCCCCAGCGCCAGTTNCGTGANGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCA
+
&D00%.+)/+*;D6-*/6H5CHEGA*B90H-E"B7#D.77BG3#.B<2(%E6)%<2F<*-004=47.'@(8@"@AA55F@*2E.9E!(<&7,'@78$A#H$D'+,A>%B+>A2'@8#F*;F"/)EH;?-BE1=9'0+3H8=7F!B7,#&42&DG$E'&HH1,;-,(
@r3955
CCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAANACAGCCCTCCTC
+
E?1HFG3DF#E*+)D'67)2(8;AE9+8%9!!($B@>$,<#:=)"<A,-A);&
@r3956
ATGNATANNNAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAA
+
(#)!$!*%&!)+*'!%#&%'&!'''$&&*$$"$%$++*+'!('+%)*#+)$$*$&)'*#($+)*&&($)**$(#*'$$*(")%%
@r3957
CTTCAGGCCACTGNCTAGNGATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGCAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGG
+
+")(%!*)*)$$$*"&(!"$&***"!*''$**+(!)'!$')"*&*$%!+*&#%*!)()**#+$%"(%'+!+)#(%!$&!*$$%!&+&'&!%'&)!(&"'"%!(($"+"'*+#&!$%%%"*(('#%"('%''&$(&'%&%$+$"""&+%"(&*(*"!())$%+#"&$"$(+"$&+)'&)(&$%''+$('"#")
@r3958
CATAAGGTNTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCNCGATAATAATATGAAGGATTATT
+
(+.0>1&+(8,8!=11"!BB<FCH4.4>8E(?17&3B%E5.A$H:6G$7B,/0!?6)$;<H7H:/7!*$=>CF#2'
@r3959
TGGNNTTTANAAATGTATAGNGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGTCATTGNGTTTATTACNAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTNCCTTCATATTTAACTGAATCTTCTATTATTAAATCNGAAAGACGATGGGTCGCTAATACGCTACAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTA
+
)#"#&&%))$%+(*()'%#*((*+(*)"!%#"'++'+#'"$&)))+'$$+)((!+)($#$!$$%"'()#(%%+)%'*+''!*"()(*$#(%*(!#%(+"**$%!)(*)#%"%*)%$!*(+"%%'#("*+"'!%#+++&)!#(+)$!+!*+$#'&($))'%!$)*%&'++(!)*!*##(*!#%+%!$+%("*"!""&$)*+)%+&#"*+!**'$"&*)$'**)("&$*#+'(%"&(#""$!**#%"*#*'%+*!+
@r3960
CGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCA
+
B0618&)B-118*'DH<G&E:7F':10:0A$$!-E2.#DA.G)>)AFFE*H3"(E<5?45D
@r3961
NGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACG
+
#H>/2"7#.>>C5HFB;+&&FH15<2---F6,.:%/)1+,E7")+8?@:$$?3;44;##
@r3962
CGATGCCCCATTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTGATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCTNATAAATTGCG
+
8%3,*G2A#;=H9E0>)4*1F(G3F9F$9";$=F(:;,2F%HF6B,->":21/6EC"@,.E$9<:!-/A,(E7=8)$;;9#-3?*#96,;*(C'>D</=H5-$
@r3963
NATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCTTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGNCATTGTTTCTCTGTGNAGGAGTCCATGACGAAAGATGAACT
+
$$++&!#!'(''!)#+**"+'*#%%)+*"&**%&+*(!(*"!%*#"+#$)""%++%("&$"&'''(&#$"!*)%*)#*!*!*(%*!#*%(#)*+!#(!#&')$&('!)+&+$"'+)+*(&%(&&''*''!%&*!%#%+)&&++"*!"$(&&$&*&!(%#$!(+$&#$!&)#"+$"%)&)##'%#)(%%%$&!$&$"$!!!$)#&%&&#*!%'#&"&#"%'#
@r3964
NNNTCATTTGATTCGGCAGCGCATAGCCCAGCTCTTACGGAAGNCGTTCACGCCGTATCTGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCC
+
%"#**!)'*)%*!(*&(+(+"$(*!!%#**'&'%#&#'*&%**%$$!%$*"$'%"!%(!)&"(&$&(')()"%*$!***"!+"+%&&&$&"&&+)**(+!&'")!*)#(#$&!)(*()*"(!&+!+"!#+'#*)"#'!!#!
@r3965
CAGATCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCTAGCGGAGACGGGCAATCAGTTC
+
*:/<0!3#F)15;0D@/EH4$"+335HAB++CG5$2@G6H2"0A3CD4@E4%&C<&8758;E.6;E27*0""0$;8,<
@r3966
NNANCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGA
+
(#)"+#&"'''&$+%$+')'*#&**$+**&)#!#''("&%#)')""&)%++%$(
@r3967
TGGTCCCGGCACCTTTCACCGGTATTGTAGGATTTGGTAAAGCCGG
+
*;D3:A6/DF'-=&G-$CD0&2(6$E0$*&G+?43'E9E92C'5F9
@r3968
GAGCGGCANTAAGTCGTCATCCCATGTTTTATCCANGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATG
+
8':CF=E,%<!90:6@F"8A2C=5.F7'&8;,9=AA",@<E:,'0G@?BH:H$4.-9F"&-9@49H0;#&:</:3+F8$9F//6A4+D"7H-D2G#)A4(2:"($.'C4:!?H<;#>@@H<-
@r3969
CNTGCTGGGNAAAAATTTCCTGATAATCGTCACCGCGTTTTGC
+
+"*)"!*%'(%!&**"!%'*!"+"$)#!)'*!&&""!!$#%$(
@r3970
AGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTATCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCT
+
93>AH#!2F/3".'+;(C>"%B3;E##.43C6$A+B$CF/24':,B2!HD6,%7H-HE'3CEC7/93:=%'4@/*-&95@027E0+7<D,@"<3FDE(=4-.?-"+>D&E5737/.0'"/;"//?A:)@)>8(''./"@*6**D<A36*;4:<HA4EB9$?8+DH#$>47:5?5A/<984.454DG/;@2G5D?H24+6;2G;-D%:1=$F,8F)$+B?&33F.CF)H/'?%0)@=6&4
@r3971
TCNCCCACTCGTTGCCCGGAAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACANGGTGATGAT
+
#'!$&!*(++&**&!*($$!$*&)""&*#+*+'%!&'$*%(+#$&*&&*!%*(!%'+#%)*+&#(%
@r3972
ACACCATCGATTCCAGTAAGGTTGATTTGGTCGGANGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCNCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGAC
+
(00'>&/)5/6.??4*+44-H80@6&37EB0$'B%(>"D=H=((,0%!G@!:@""-73<B7>!:B<96)BH@C*C8#.>09!F.D4"-;)H#@$C:<C'ADA#A2G&67H4$C:%'"0:CF%!,,,,(D.)C4;1
@r3973
AAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTA
+
/8G!:&ADBF(C)2#"C5??:05&.$*7FE4*)7@2182$%,A@(2<?75+0.+/5?-11F".$?3.17AD.)#27,BA;46$AH,.,(&:)#-.AH.%H0"H6&8/
@r3974
TGTNAANGCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAA
+
%'!*#*$%+#**$%+*#+&()*$"+"$+")!+''$%*++"*+!"&!&!'+#"!!
@r3975
ACCTTCTAATCCTATCTNACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGNGATAATAAGTGGTNGTATCCAGAATGTGTCACTTCAAGTNAAAACACCTNACGAGTTGGAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTCGGAACCTCTTGCAGTACTACTGGGGAA
+
;<,=@H=@@C>>@=4A'H$&,E$C@BB70C-B1&7@3731=:&<,*4()A@5>:'@--,50G,CD4(<>0)*7<60$:E@,8B.7BA&G'$78BH1.+C@7GE/7.A./7;*?C)H<H-@>>.1;"17+%2.@5)4A<DA.==$@".9')?!?3%%.),A)*:#=G%A<B$;/#;3":$(<:-:H1"CG'(83!7,D.>?%+1!C-?A40",77DG1%2,*'=#&$<H"#$C9A0/(F#:!=*H"8#%D:
@r3976
GTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACGACGTAACGGTGG
+
=!E)$B*E-;C(7@8H*##G:.;7#&:+-66,2B+=>'6+#?>(&5*5#,'5(/=
@r3977
GTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGANTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATC
+
G-.C,39,G!.=,#+$2?CC>FB/,AEH4/H)CH$7C?.-,'+/<6A216<:(>>4$D:/&D>E.+F(;?=9H<'<#7%"5565:&3E.:*"8HDA%#H;-,(=#"'4A@+:+:*'A9@?
@r3978
ATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGAT
+
C,"7#G7:%/-B(1)A?1G+@C>3+D?0?C?:,:B!:,AD$41>!#-0-<%)0!=7D:"+,67.;.?-:E(B?)@>(B/+-EE69;)@G"("5E6$&B3%2#6;<H&)":D;6.A!BC)E3AFA?E-F.4DA80#
@r3979
CTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTC
+
2BF-F&%8)>)E%.-072B;G?92C*(F=-4E.E34?.2;(!82G$/6&5&#52ED,C714>+C/"$1*<-7,-0BE28-"",BB9!50*)':!..%,8BA/A6G?8#.6?#
@r3980
TCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATANCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAANCTTGCTGTCGCGTATCGATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAAGCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGTACACCCACAGTGCCAGTGCATNCGGTACGGANTTGGGGACGTAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTT
+
'+"$*%"*+*"("%)#&$")+)"+%!(!+%#!)')(!!%($+%+"$%&"*($!(%")%+''&"'(+"**)$($%&&'!&+!"+)((!##"$!%(#"&!+)!%')*$!"))(+!&*%*!!*&))%%*&%+(&"')'$*&#++%#$#$)+)(%"%*#!*$%***'#*$%($%*"+*!$$#")!'$#!&)"%'%(&(&$#%+!($+'($!#&*+$!"#$$%&+)!%*')$%#*+'&)"'%!$'#&"$!"!&*%%'(%#'&""&)+)$$('&(+)%"+'"'#+''!#!"%!("!+$$$*$)%*!'"(*%*%&%+!#$*##'+#($')'&&*+#($!#+)"("$)%%&"))"+"*$!(!+)#")(''%*'&$&#!!)%$''%(*')*%+)"*%&&#"!$)'#)((&*'$%%(%())#'%#*!*+'
@r3981
GNTGNTTCCTTTAACTGTGGATAAACTTCCTGTAAGGGTTGCTG
+
)"$'"+"$)+&&!**%"&'$$#'#'+*")!!*(%&&+$+!+!#*
@r3982
CGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATA
+
0:<$54>&;G)?>C73(4?(*<6-2>+DH+90:==:&B//=2-";GD@#F'-6<,7=!
@r3983
ANGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTC
+
"(7+B+(4A$8G:=8?!/3!A;D-"/.F#+7<-6FG0D*>+CA96A47C80=22;'?F3=?$'7/.#@:CDB5
@r3984
ACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTC
+
3-GB.@9C0FD5=D>/82/3D*CA9#BD.)A!')#9=72B+*2;!AA+6FD
@r3985
GGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGNCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAA
+
!2">7E$<*(=C=GAD>";&87/8E+*7!5E<BC:8=(1964,4565$8%7#-)39D(3!2?0/&$+(.<5B&-/.0.77034''HD=?6.8888D:A5'@54!BDF(/:!G,>->3D<.@67<B<6!&1-;*4BA9=&4*4/'E&!'F?$."-+>?3*;,/(-),1*/%<3;.0'0.-*%(D@:+AF%4556
@r3986
TGATCGTTTCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCT
+
C!H+4*0<:$8-*#;0%+G;9*@).7F(.</3#31&!12C<17D3;3GG8)B>+
@r3987
GCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACNTCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGA
+
'42608)1#$+7><36332#*39>.!56%H2)6/C4!#:1)6?6-4:&G+%9A>-'-488G.%??D7,)GB*BH8.'3%)91+,+4''73>51+!C":%A1,;&>E.B-7/#1E&C<.@'(AG%*5*@H*!61@9H51%--$*()1..
@r3988
GGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATNCCAAAGGGATATTTTCG
+
GG4B.22(8>$-20%:9.DB*(27E.8*@9!B%E#">*64@?9H$;F0"31(6D@4,2!6?+&887+(E&2$0/G!?#,;$+!-21$%*
@r3989
NCCTAAAAATATCANTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGG
+
#.C)"%A-B2(;1)E>$?.$796D5).62E.&E3G$F8(:93*@G.F&H5BE94"-.404@*=?/F-.',,(%C
@r3990
CCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATNCGGTAATTTATNTTTCGCCGTGGAAAGAGTCT
+
C4%B@%")<4?FEH<#>.@;#?D/D)*H&@+7G">?1#((('!->#H!#)2*)*:&4EH<&<'5'/(?<)64/+4GE.87F*B&-8
@r3991
TGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAGCGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGNCGGTGCAC
+
;)$H!$4GH5(07!E#GG64:&69,51(C03(3/3*<6:@:.D.!D7H7@;%;AG9:91',='9?#<?)@<4"',99+8";.*90$2C)(AA.F>DED-47##!A8CE*$;8>@-=15'B?00@68CA4):9"7E2<C&$G:GA-C:C2B"5/H=>>?<.3E
@r3992
ACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTNTATGAGAGTAG
+
."100?)@CD:"8(FGA9($!"G)$0(<"/.7B,1E+9GCE&:7''(>4;#,:5=()',,2*2$:8)""4@H&?&&(5<E'<)-#D&7<.)"7*C-/CC%:AB=;7(C9
@r3993
TAGGTTGCCCCGTATTCNGTCTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCAT
+
%0,&E3")&'F+;46'F409';*H9H,-!C+@)H16:>66))'3+/B+-%1FD-2:6.E!/7#+B!=,?!F0G24F9A"E'6F$E(,5?5F(*'0
@r3994
NGNNCGCGGNNAGNGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACNACTNCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGT
+
$&#!(%*"('$()#+*&!()**#&+!"!)&)%+#+%#+&*"''!)&$$$"*!#'#+(&*!!#&%%&!#"'$(&$%&(")#&)!('*$$)(+)"()%(#+$#"&!")%%$""#!*#+$+!#'(*"%")'(!+$%*&*(!+!$"(")#*&###)*%#(&&+")"+
@r3995
TTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGT
+
+=3>)C:2><A:++3?&!H.9C7"H1,H!HA0=)./A#?*09'@G40'7H#%C;;4738%!!<,$:2;E,
@r3996
GAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGNTCAGGAATATGGTGCAGN
+
//D-F/(1C#B2C<HA(=54@<"06<@F8.;?H:B>?)=?CH#0(D!':?@66!7>,B855>C&=A.1@6?"+6#(
@r3997
GGGAAGAACGCGGGATGTCGGTGGCCNCATTCTTCATCACTTTNAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAAACATTTGGTTAGGAAAGCGG
+
,+C!:59=8F-'EC'/1/+6"04C#2:@@,9EB!+:G7>@:':$$7'A$7416;+1)@C27&"72!#GF;1D3=>HH8FH<&0B27>(6<B5F1>,(06FEB9,=EF=>BE?'D#)75C'AD&H<,-?&("F71$:9H1@6AFE(1#79*=BD(@5H!=7"H,H/<C7+=)+.(<C/
@r3998
NNNAGACCACGNTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTNCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCAGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATC
+
)!+##!!$))*%*'*!'#$#!%(!)###%(!#$$*++!*()++(*)!(+#+*"%%%%$)'&')'#!+*#'#)+!!)#&('&++$"!!#+!&(!*+(+&$+(&*)(%)*'!"&**'#"*#+#*%*&'$$(%&!&)'$!!(*("+))+$$&$!)!))+!")&'*$*#&!)#(%#&+($"%#*%!*%')*#&*$*$
@r3999
CCAANAGATACGACNNNCATNANGNANAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGAGTCCTGAC
+
''$!!"((%$&%)%)$##(*"%(#!&!+"(!)(%!+!+%+)*++)!)(%*!#("$("%$'!#**$$)*+#(#"#))"
@r4000
CAANTATGATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAAT
+
')##*'"+$*)"(''"*+++&+"'*"+(&#""%+%$$+#"+(')+%*)"&+!%%"$&!&#%'(&#()"+%&'
@r4001
ACTTGATCGTATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACC
+
,%;F+DB*F!G+4DEC<,=)4%/4:&>;$$',!16G$;,$;,#G:B89A<*
@r4002
TGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGG
+
7120!G?D3AFGC!-65368CE?(G8B2:HG/C+1,7C':FA+,%&0B*8,H1D@9+
@r4003
AGCATGTCTGGAATGGTTTTTNCTGAGAACGTCATGCGGCCTCACTTCNGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTAGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATA
+
?%BF#4)1:?A&<3$>!AF(5E0D"5>&4D53('6H0)-,17BA($(.<;,A?6>1@B3G<*14B(=743(0,')H74*5G#*38==**4!&2/B%%!=<.:D@+CH7)%'9'3):0.0$>)6C/F6"5G?/",8)B2@*>@&5"@*?96@%D.9#8/$=@FC"G=%8;-?A6E0)<HDA!+%HCC<0@"4,G
@r4004
NGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCNGCATGATTGCCACGGATGGCATATTAAC
+
"B)4F.6#9:>6*;B#%,+%4A*;$</.6#?085;"@<F-<0)/C)*:-#BE;/,A5<6.0"%3-ED,*5>G'6!&,&(7999=
@r4005
GGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTTCCAGCGATCCGATGGTGGACGGCATTCTGCCGA
+
,E-A5/-AB,D36>3=521E!*G,/+B(G22,'%#%.-1-!6>9'8>4D)(+8*/707C3$%BD0D%DF4;!!F8:B#
@r4006
GTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGC
+
9&$5(G"3>(%?*$,=02/C5A.GBG0$&%?73E"02;D(68D3B*4-3%!*/<"D*'$)DH3'GA"9505+<%-5)=#!&B>"(1'0><38*B@D=>DH-E813$863@"!"9/#D:*;>1;;+F,;-'E:@,.2)'%?+G(4.*=?<)4!-9CF6+'3G&#4134E7D#=:!/H25/,;F/G
@r4007
TAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATT
+
.5@7AB0@4(#FB9-'G195,%6.1ED:74"/8@<88@8B9;$/8/
@r4008
CAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGC
+
B;7B#<9?6?1-H57.AG>%?<4?F699+75B%"+,C,7'=7(D8C,G;%D#,)E'+4:,C'
@r4009
NNNTAANGCCCTGGNNANTANNTACGNNTCCAGANNNGATNNNGGCNNNAGGNGANGNACNGNNANNGATNNNNGNAANNNNCGNATCNCNGGGGNAGTGNNC
+
$"#!"!!#"$"#"#"##$$$!""#"""$"!#!#""#!$"$!$!!#"$$!$$#$#"!!!###$#$$!!#$#"##!$!#"!!!$$#$"#"!""$##""#$""!##
@r4010
TTTCACCTAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTA
+
&<07732?01>GHG"0H=,'?!";H*954&</?&EH'$1.';&5H+1&.3-
@r4011
CCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTNAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACC
+
!C5!;4<*<D8B583=+95?/?8).$6DG"H-65H#?9A"C3D:#D3/4'1F*#/)H>!(4.C-6D6D6!@;%%1,:',(F71.(;'!.,+9,&4.1=;+)0<!);3:">)8ED-D0:$=7F@5E$''D048:5"5&:G!2"(;?7#7$=,35FG2::)A-2?E65$A?)0"*6,??$5&(G'E"F3,D&"0,>D/(E.*5#$,D/$<
@r4012
CGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATAC
+
F=?/+(:A">)5.8G6+8/A*AF%A*,<7/3H/GC;5%DD07H"2+B:*8>+4DD2#%9#*
@r4013
ATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACNATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACC
+
.*.>11#&!BF3!6!0%!/&)B"E%B880D-1?8238&*53GBG9(+63#(,4&10C>B*';$(0=04+')9%#%!&?F(CB!-*9E7,?-%4.B8BH5D45G$4?30E1#0*%@3BFB+8''%8BG1F><F=BA9??A=2+
@r4014
GGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCA
+
&B=(,:',D9F=D7/464;D;D+37>4%5==;>9#?C3F'/?@*":!28$4B#;%)891-+;+'D65%;>+"4@!79:"9'#5<E>!%38;7(,6E;"!6?7E5,!/6
@r4015
AAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTAT
+
?3=!H67><',7@8@=2(+BF=0@'&+C:9#91@0D$2/=>4F6!H30,2<5AG-;=;8CF-?9@(?$<.'HD>9,"!6>!(H+-&*.(37$-H48@*'$+0+!?:8(5;F7'2#4:DH1*)!'G64"0
@r4016
GATAGTGACCTGTTCGTTGNAACAAATTGATAAGCAATGCTTTTTTATAATGCC
+
;:68<G65CH&*H-A=77/6++BH@B(0!-","G7"5.HGAF)/)2+24E(!.*
@r4017
GAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACT
+
#+&&'$'$$*+*'*&#+)$&!*&##(+#&&!+(&++*%(!)+%"&
@r4018
GNNGNAAAGCATATATTATTCCCTATTGAGGATNTTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAA
+
$$)*&&&+&("*"##'$%&"$!"+'#%'#$$(#''"+*""&!#**$(!%%+#&+&'+&#'$&$+$&$("'##+'!$%&&#%$"+"
@r4019
AGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGNTTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGGCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCGCTCGTCTATCTATCCATTGAGCATTGCCGCAATTTCTTTTATGGTGATGTCTTCAAGTGGAG
+
+)&+$)+#$$+"%'"$'*+*&"+()+)(#')"!*$$++#!%+&$$"$#)%++%$*')&'#+(*("%%**(""%$!)$"#*%!#++#*)+''*$(#*&")"(!)+&''''$*(%!%)((*""'$**)#$%&%+'+++&!"+&"+(&+'*#&*'&$$'#)!&"'#'!'+")&'&$)#+++'""!$#(!(('"!!!!#*"+$$!++#''+"&&)&(%!"'!!&"!#&$))*%&(&+&+"*%!+#$+""%+#!&*!)*$%!'($+!#%$!!!'%((&#()!(
@r4020
AACTCTNTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTNAAACCTATTATAGATNTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTCCAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACNGNAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCANATCNCCTATGAGCAACGTGNTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATNAATGATAATAATAATATTAAAAANTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCANTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGNCTAAAAAACCATGGGAAAGA
+
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
@r4021
CGNCTTTGGTCTGCTCAATTTTGACAGTCCACATGGCATTCCA
+
&&#++"#""&&"%$)$'!')'"$(+)(&(#(+$#(%)!'+&!'
@r4022
ACAGCCANAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGG
+
#2)C8D*0>*.*-3<!$=6C23,66,%3=C<E0(0*@<=G*(7A.(E43"
@r4023
TGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGAC
+
4:+.-;??:7"@';9.,*303,;!1A9@>&+G2G3$.4*/$
@r4024
AAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGT
+
02D?4@9@*9337;,(&D)56C542B194;-$*<7B7>7++0"$-53#40!(56>A"$'";61:=%3662=@8CF$+G,C&B1#4!8.+D=81(#C+8,,'.D)
@r4025
CTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTAT
+
<((5)G'C$756##F7(4*?):,'"08=;F;+B,-:.:82%*H.&:5(/1*#%:%/36:G(/0'E;D).#3-7*?&;?#E9<6@1)G?"@.E;-
@r4026
TTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTNTATCGTTNCAATNTGGTCTG
+
.E4!@?%H,058&0)0.&FG(8.8#==:?.#<80/D,H2"79>,!*F8+D&/#CG%-A'8F&.'7="=$A8,-B-H%C05&;F%#=<=9!=-"1"4,C2$&!H";#@,0HDF1?/*(8
@r4027
TAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTT
+
=?-2D'!.2'=%+&7/H$$C4598%$46&+EG04E/:&A>F%71@$99GG#4$(A8G$2B)-7'1'
@r4028
CCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCNCTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGC
+
HD51)0B?8417H)%=0<)5!84:C!@E--?%*;4,6EG)8(>B:"*G&!)1E9/-<,#.BBB%*%&>8*B,2E,+4=':55&EH832!(BE79&@*;@6:F%D>#:',<3>C@+"8?/+
@r4029
GGTCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAG
+
#))&")+$+&#*&&"!)#'*(&%)*$%("+&'")(((&$+)&#*&$#
@r4030
TTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTNTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCNGTGTGAACCAATACTGAAAGAATGGGCA
+
B&6-+*C1*@;6.)2'"@3.5*$@&F-,E?(3F>1@B65)2D)#*-@'?(@-4?!$?=)@:775,551A!=8%4A?F&(3(&?$,%?5*F<=!$B.=/9/+6D5A>50/F40D20A.D8'.B4,>431$76@2/2!.8
@r4031
ATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGA
+
/E8C#8E8:BH-#'$<@G-.<%.C%E6B=0C,+*;$>%?>C(?,DF-1;'G3@<?>?CA,E?/*A7'%B?:4@6/?(D-=%>!.;5F0E,B=,76(@:>#2!E7)EAC''8!H%-A$C9A2'5112
@r4032
ACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTNTGTGGT
+
86+:8?%'D:@EC/*F;=;8=;+E-/+C@%!9!(?89D>?"31$:14)A:E'2EA?DE
@r4033
NACGTGCNGACCTGCTGGCATTCTGGAGGGAAATACAACC
+
!%"($*++&)%'+**'%#**)$)$'"&*$#!'(*%*+)"&
@r4034
TCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTG
+
"H(D=+<&4#@B/*!;5$9D($:3:90H.?5:G>-0HG/3,B>G#.@C4$!"09;<F;7?FGF?F1:32%3<7;2"F?<)9%$'EGDH!(,B>H
@r4035
AACACGGNGNGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGG
+
9#1H2"-H$$7@*A9421H$@*E"BB4($7!?03*2<3HHE>BG!.%($4C?D6<
@r4036
TCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACANATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACNTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGC
+
5>0750&GCD+@95("!)"76+)>3A<)D:###"F?3&3+##&?5,8$;(68?3)2F>033)':D5:<#F3ED9F4$'"5H;G6<B"A-GCH8#<%$=!A;-(2)A/!2DE-*D#EH:C#'?(H'F$HC6,;>;>"-D>@26H4<!$@-5!=A/+C8)=#:$,7;B#"D@'HF+E911#.8,>?(/098F!4>7#"$+#?*+*3;>6-3+70C;(
@r4037
CATCAGTATGCAGCTTCACCAGTGCTACGACNGTGACCAGTNCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTNATCCCACCTC
+
?"47G;1:>-1GA('2@!F:E1$8'$=+:)H5*?*H/C9)&<DG1$/CF"3-5BC?&."%'=A6/%(&??3HA:3H68'/D#,=H8G)
@r4038
TCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTNCCGAATAACCCGGATATTTTTGNTCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAANAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACNCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCA
+
"(#;;7+($>F4;GA)E?B0-G.?5!*@G!))4.,=CD8<1C@-;#2E+,B?>.GB$)4.3/D/,+139&ABDB>*F!9;6!##'3$?2?7,.)G/$/+B1GG(B(-@9%C4%B3#;+9G13H142"/,9E"+62@-!DGG>DE;?D?.&>44,6G;+EA;'G,-G849$@;E1F>!/B!#.5>?&9.*1+<?/!;>2%3;&$%'=F&.%!-@8G*G+0<A&+1@H.?8G(#$='1.F=*5!"9D37$+0(#E*4)
@r4039
GGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTNAACGAATCACCCGTAAATTACGTGACGGA
+
/)!GB8G)=$3!8;*&9-=;?.*48.B+G;DHF1E+-@=27*29?:=!'!68.+=D+7(&8?>+,"?47
@r4040
CATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCCACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAATCGCTTCACAC
+
@4)BE'63A4$$6A?)#,1><G$-,8+A@65"14DEG&/#'B;*+&%C?7?7$78'?/#,)8.;(%0(.;?@B<!>&*HG)D*!?<4?B:A$'7EG:=?F(>;&,HE?D.1!C(F1>H<D(4#=20.C:=(,>GH930=67"*F&/CFC$'(
@r4041
AGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTANGCCGATCCGGAGCAGGAGGTGATCAGC
+
0>A&)),DGFG75$"&?8;F(&)'H-3>"F&H0))>DFGA#&7->).=D,2':02C*F.7G5D?"F$94@*0/8H:G,D2
@r4042
TGGCGCTGTAATTCATATTGNTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGNTGCCGCAATTGCCGGATCATTC
+
F#73!7.:-4E$#0";9@4**)0%B"5*0"7,($E$!3F552-,/%16&?.81/D#D!.,)B6+CA=7E):)0'&-#$B.*45+:-1B)(F=%9!D#
@r4043
GTGGGTTCCACGACCNCAACTGCCCTCCAAATCCGCTGCCACC
+
@,+8@6+&.G*+3#4-66A2&7<<#%<==F1C5"B$$*2<</-
@r4044
ANACAATCCNGCACGACCGCTGGCGNGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCC
+
("&$)$&!)#+*')#($*!%&%&$%)*#$$!$)(()$##&"'"*&$#'')*!'"$")#!&'&""&(!%%'##'&%!&!!+)!(+++*(#!)+*('#(&%(#'$&$"($+($!'$)!!*
@r4045
CGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATC
+
=?=GBG09A:72*'3.C@G+).+.8C#3,730?8E7$./&66'-7.053-+A-5+5;F&;?G+-&>9?>=<F<&HG9'?;C136D:0.08DFD/$$G
@r4046
AAGCGCATCAGCAACCCGAACAATACNGGCGACAGCCGGAACTGCCGTGCCGGT
+
DC/.@)&%&;565B-=/F9E?D@B"%,',E*@07E.1"5D/C+'5**"(,16'9
@r4047
CAAGAACATCTGCAACGGAATTTTTTGACAGAATATCCCTGCCAACCTG
+
?57#3H:B99#(24A1!3!H:BHH<H58$-:*$67G-*>0(?(&-!?/=
@r4048
GTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTCCTCAGGTCGCGGCCGTTNTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGANAGGCT
+
7/44C=>#:<,6=1+7G!D-4E%2>>4H92&EG(6@))9G3$,'.)4*>95.'D.=*H681%"C/:F)">+!%;3!BD->F73,F@?-#CG1,=9G$=!0+@.'/+-%2B.:(DAFH2#?<8-)DE%#G
@r4049
GCCNAATCACGTCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGG
+
-)C%F5@:88&3@83>0A)3/(C<'#2097B)7GD4>8<347<)C):H0=39',E'95FH$@14+:2-!?@2(6?!<@$!8<?1(G"@D08$$6
@r4050
GTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACA
+
E-C8"12F8@:#,H$.0;/-87F/5/:DG4F2;1D37;"++%0?('FC7D1;
@r4051
TCAATGCAGCATTTGAGCNAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTT
+
1G(;/+3+*9.,<6)ED"/8BE0G&A'7(<80=09753G9-11<<C#F.=(D8.81H$#&-?*1"64##8%>1CGE/@305HE6/5.8
@r4052
GAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGNATGATGCAGATAAATGTTAGAAATAATTTCATCACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGA
+
B0.H<7(1$'"4,-:7H-F6'H'D)'2.7,<09<%&;/..G9:.F;H$4.)0G1C*1#*')535)9777D:GD:894&(*.!;DF=86@2E'H-?@%>A2<17//+C(C4?*F-BC)0F1D78$?68*7++.!#8<50G;745A+*=,E",@B%1
@r4053
ATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCTCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTC
+
(5D;@44+-)C8F%.;A7%7@F.%<:%=8*5$A,F'D#).<<%-0C#(!%'G/2C0#)6G+23-AA,?<)<9C7@E+5'4:',"E@28E>;"2HE0@&$;/*5D%:4G.?(#F<506'(;501G,@A,3H'73</)?$*:'?"0&?#D1=69>)7F#=%CC>!@4
@r4054
NTTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTNAGAAATAATTTCATTACTCACNTCCCCACTTNTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTA
+
("+"$#&'"#""*'%!"""&'%#"+)$#)&++*$"&%((#!&%*!#&$%*$&"(*(+!$&()'%+(')+%#)$+''#"%!&$*%+!#"!'!&!)&%%%$&$&%)'+%+%*)%""*$#""*''(&*%'*"&$%**&)$"(
@r4055
GCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAAT
+
0'<5"A8;:G9!E(2E%'3%6/EE9*?'!@,?E1>B.6<B/CG-F6:$8
@r4056
CCCCCGGCGTCGCGGCACTNCGGCAATAATCCGCATAAGCGAATNTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCCTTGCCACACCACGGTATTTCCCCGATACCTT
+
5%5B-*.99B3*>%<0D>?G2+<HG3E65):8B*F1>A-DDG,(+$.G>%=>''>8",#9'?-/G5'5@8$*DD7>(81*'06%3(5BDD(G/'*2+;D*#C%4)&(79#91@B,7:?2C@
@r4057
TCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCA
+
3B.9;)EF+E/A'.A2,:;7#96011/(&5@98EDCH6A&70C>;$<!-H$9<!<%935*3(2C@/@:!5"06/6)E9="?,5?!88.>,H:@69=*0060EH0'7$+,+4>B?304#5@
@r4058
GGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGNTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATC
+
+.(/E,$1B,0/A"1='HD8A??=<1+:8'32:=?@BB:#54-5#*?-812$2.60E9B');;>?E/%0>9%)#7!D>HCB5+?%D<*-4$:!@#)"-3'C35!(E@?"-!
@r4059
GAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTNACCACGGTTAATTCTCGCAGTCATATGGACAAGNTCATCTGCGGCCTTACGGCGTAATTNCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGTTACAGGCCTCGCTTCCGG
+
7G!),,988&2DG6=G06:(69,4%;6EDH%.+$'D671(=2!$>()HHH+/0.9'F<0=E7!-D%?08('"A&%.#6//!E66G)$'#H/FBA2)*"BA8-D$?G0!6F-5+(H1B$,-"0;EC!55!/904CB3;;8>3@@8>..H/45(-:-!!$<+&C9#7.(=$?2A=#,0D444%B6G!7GH:--5D-)'G+;;4E1388B$?8#'1A93D/;*A0;A1?<
@r4060
TAATAGTTACGCTGCGGCCTTTTACTCATGACCTTCGTGAAAGCNGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTT
+
+!)#))%)'+('+%!$)*)+")!'+'!#+$$'&*!*!'*#%%&"+'"&+!%""%+)!*"%*!%'"()&+%#%(+%"!(!$"
@r4061
AAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATNTAGNATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAA
+
3E"+?')9,-02G3&)4=)7""%/CB@0385;&<8$B">#A=6EBDDA)$42%B'+:).G)H>':'-7(G+<+,-%25.&-%2)H>H'=='
@r4062
CATAGACGAGGNCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGANAGGCANTAGCTGAAGGCCATATAACAACAAACCATGTCGNTGCCAC
+
-&>88&AA&,9B17//8#8=FA*2=$9BC$,9:6DE-6>#>?6H5AG#->7,1/.54"G;=(:1F:-$@G?F-H;$45>46#(=!CHF<GF+DB=!F<F?#6<"6F807:E
@r4063
TACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGNTAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGC
+
H<3%8EBFB%!*6%/:1@%0B"D"4.B0H*.0*&2'3>;585)G2,#(+,&@%BF7H2*49=",0C2,-)"0=/$C*6F.B+.%,,A@F69"%"'42GH"&);5."G&)-D=35*B3+E2/2-%E$!EF'(&/A1,;D@D
@r4064
GGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCNGGCAATATGCGGGAGATTACGC
+
7A#'31.>45%<D.?#<%#.C437$%3B+7%B0@">9':756+G#"<F?G%/=#'B@
@r4065
TTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGA
+
8C'"=C:6!88F!55)D"9G:9;+:GECA-!4H%7#H:#,%1-(,E9:A
@r4066
GCATGGGGCGCATCTGNCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATC
+
<)"C8A,E<7,.)BE94)A:+E<H(%7H76?E'.A"413#FD=7+&()-4:B?7307<G-9/=$5*G49?H##433%9A!6)!':/
@r4067
GAGGATCTGGANCTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTA
+
>A<4#$')-$H(BH12+C?.//:#G+#9!5@*/;<5;5606"9>-$<,D#'
@r4068
GCATCNGCAACCCGAACAATACCGGCGACAGCCGGNACTGCCGTGCCGGTGTGCAGATTAA
+
,D/!G!,&1@5'97>:9F%0)(+1A8;C;.8$/7BA()@/1/."'#$=.?6@4:F&FF@9=
@r4069
NGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTAT
+
%=>$AB!)?*3H+C)E?68+=G-'#CD1:=H&!:C/+6%;6*D78:6B=:;?D4<DFB1%&6"+0$95&,:$?<."3DC:;=7!H1@-3B<:3:*B41"28#(
@r4070
GCATTCCACTTATCACTGGCATCCTTCCACTCNTTCGAAAACTCCT
+
*?(/C;8&D7HC?G8$D,38$"$=FB'8E+",.*6,#D4;AG-'#6
@r4071
NTNATANATTAATGGANAAGTGCTTACTTCTTCTTTTTGACCTACATAACCAATTTTAACATTTCCGATATCGCATTTTTCACCNTGCTCATCAAAGACAATAAGATAAAACATTGTAACAAA
+
#*"$(!$)#+&&$'&'&(!)$')&"(()$'&)#*+!)*"$'&)("*)('$#*"(!$(*")&+#!&$%'("%+!%!*!(!&)#*+(*##!###&!$()+$&)!("("(&"&+)!&)&&*#+$%&
@r4072
CCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACAT
+
H/E@63%H=F?>!,#?)''G"=GD&4)%*>576C0G"5F>(A@<;3679+?H1.(=9&*6A1*2/$!)'B"<'+@?195%*!123D"%
@r4073
NGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTTGCC
+
*7":<*E:%'",0:!9@GA!>?:.,1)+%)>:1=DAE/@@463*@55#G(0-:%$2C&3-1%E"-D2E258A>G*H..?GC<H$99E+#=5+BH<:*6A&?)H#&"(:*6-?9>
@r4074
TACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTC
+
'?97>7G-G"6E91-?!-4DF7,2E:H78F*+;#ADB3<DA-4B#F#9F=%
@r4075
NACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCATCGTAAACGTACCATGTCCACCTTCCGCAC
+
!;"<8'A7.&-9>)"79+!7D:+5D3$;7&)9"9)C:''C&H7?#+@B524%.73AF'0<>7,@$3<51)7:A
@r4076
CGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGC
+
7%'DD>&7A37!2G.>@%C*1?E0(G5=6GDFE'1>2/?B
@r4077
TGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGGGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGG
+
<9-%*=9!')&3!)D72163,/!1356B1(&B%!."AAEHGE3H')"+0@/A4EB5<#-"#2B#?!A"HH5G#7HCA8%59:1=@.=F=4="A*(/(>6@F+7<09D$.)*32@;("3&0*B#(===A'1:'+974)+;&6)D?!#-=1C.5#@""86;@4(<=%-/C%90$&5%5;.3,9A<("@)3##)G6<<
@r4078
GTGGTATAAACNGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTT
+
$(G;":!&$9</0C.*$6C0&#>3D8=1&E053@)08&+#%A$36@E;'7G.&<H(-!2)13>&)+&&?=1G#0>/).!E9:524..@#$-8;'"0/(%D>>
@r4079
GTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCCGCGAGCTAGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGT
+
+$&'(%('"%+&!((&#&(&*$'"%(+*#*(#''&$(''*%$(!!%!)$*%)%#()%*%&#(%+(&"$!%"!!#&(%&$#&$$!)$!"))#(*+'(#""+&)+&(*$(#%*(!"*()'&('%()$#"'!)$&"!')+$("+(+''%&(*$+)"("!%()+!+%'!$+
@r4080
GAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACG
+
6<;??&/E.H?!7!3@!/GG2@8BC86(2&-05&!:8$&<00.&C
@r4081
TCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAG
+
(D=;CB6%&8A;2'(<?/C1H?6!;)(!1/02?412>70;2ADBB:)?%3:5*;148FG7EE,>1A08>-=/
@r4082
GTGATTCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGNCAAGC
+
1G0GE=?D/'1".=<A?GG&BH=?!0!F"$D2#B##+2F@+(DAG71/G3*4'8EA88@+@3D"H7E>
@r4083
NACNTNATGANGNNNCNGCGCNGNNNANNCNTTTCNNTCNNCNNNTNCCGNNCNTTNNCCAGCTAGNGTTGCNNCGGNGANNNCNGGNCNNNTTCNTNCGNNGNNTNGCNACANT
+
!#$#$#$##"!""!#$"$$"!$"!!#"!""#"#$"##!$$!!!"!#""$$!!#"#"!!"""$#!#"##!!"$!"$#$"#"$##$$#!$""#""#$#"!$!!#"$"$##!"$!##!
@r4084
AGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGNTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCC
+
7#)E,0+F5G(/"C>-H2DH53HFFG@/1@@4BG;@4A%(H+..+H0#7$=>3FHD(E>&A%55=5,BH7'DB*'HF;*H*C@?8H)%G?AG.&:?D>0<257*D)21)!F;>+!CC5"/**361?*71=>95*2B4<0-5G9040/:H6$;4'C%*999$183)"&#'=)<33B<$AB<H(.D8.:<2.7;AD!*?<D
@r4085
TGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGCCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATC
+
+!4"./=A633)101!A$D$<'?CH9+<&*6(DF'-4.>(%@=&B:BH!D.G@+7B/;*##HA:@";@&2>H%096='&>AG51()>G8G%H0,*,%H-3G'0F<&81!06:&'%1)/:-@16;*;
@r4086
CGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGA
+
!DG@*8+,1B'+B.0@'AHDB?AC%@+D>591F::H@%DD+HF!G?76-@
@r4087
TCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATCAGCTCTGGACATGCAATTGCTTTATTTACTAT
+
:C"76GE/19??=D112)>3B0:E$=46&,"8/=F*832&7?AD*(:'@H*7&%!<7C(*,0F65.6$<)FDH/;@;B1
@r4088
GATCCNNCAGATTTCTNCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAG
+
"%(%%#"%&+&*&''$")+&"'$!&'$("&#!)*(#*#%(##''%+#'$+#''')'!*#"+(')%&"&+(&+*($#(%&$***'("&$&+*(#
@r4089
ACAGTACNGGTACCTGACGGCCAGTCCACACTGCTTTCAC
+
:*!H"*+8)%586)'E'B?6A#A$H1A1F?E$=&:5+4:.
@r4090
TCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCT
+
+%*!()"""&$$)*!!!#&$##%")('*")%%$%"%%$!)%!*!#%++&'+%"%+*(%%)!!#"%!*!*)+"+*)#&++''%*!(&
@r4091
GGATAATGCCAGCGTCGCGAGTGCCTCNTGNGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCNAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCNATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCC
+
1'&#9!F#'12C-&0%,0$&2H*5#94,6'F)!"F8G("9'='!*:!4#C-@(98.+EG&86?"9!4<57,-.*$=@0$D17F(0!!6/C(&H'H7*EH".#>AD)*=.A??43;GDE</111D2A?B9(<HB;?5>26CA&+5B:<*4.80%22+%--!4@76#=A;:F/$D">4CC?=3:9@46,()=",!9-5C9ABEGGG">*<B)",(GH.=!/%F1/
@r4092
TATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCNAGAGCCAGTCTCGCTTCGTCTGACNACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCT
+
9,(=+7%9<8"4*-$:'4&>(2C/!&.D1C$%0>4&?%2&DF@$$?B2+:EC;G$5H$?F-(.DFG+%A#**.CB3:H<61+%6D)9D,65<DHC+*CF36E55.0+6C3D,!2?&&4<*?!"'5#B>D>G.7?5@*?*B
@r4093
ATGACGAGCAAAGAAACCTTTACCCATCCCTTANCAGCCGCAGGGCNACAGTGACCCGGCTCATACCGCAACCGCCCCCGGCCGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTG
+
+(=<5H*E;/*24DB74+"#.H,24$E%6%+B&C>-AG8H@?8.BGD0?3$H=::),,E%B=30-1;D9;"'5(:6+);!*/%=E$->/9*;()DD3?&)3@,#)@>!H!3@+)+)C1
@r4094
GTGAATNTCANCNNCTGTCTGACCGTAACACCGGACGACGNCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCT
+
(&%'%%"*&%!""(')%+(*+*+*%&")((+'%$'&$"%("#$&'($+&%%"%'*$+'"")$%%%*&$''%$#*&$(%##*"'#*+#!!'%)"+'%'&#+#%"%+&!
@r4095
GCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTT
+
G+6<'0AG",713=$1?,<8'<84>A3.)FAF,<1G+;'8!07#/DHCD68'G
@r4096
GTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTT
+
2DH&98E#H<%F:/0E,./!90:&0370H9B40C5%/H3/%1:,"A'!@5F/?:.,6A176C>>-&4.<:82.30!?G>%F6;)&E45#=7:A.:
@r4097
CGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCNGCGGCTTTCTGTTTCAGGAATCCAAGAGCNTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGC
+
,#/#8:?),:0A<&<1'+4!-#37*>/H/H@>8C#C@F"E3!D&0BHC*8*0$A9,7%B/A/<%9-;5+<21*8?=4!+72FC>#@8:%9B3>:H?4,0)#7,DDG#(B+6?C/HGC0#=.@B*G9*-2,&
@r4098
AGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCT
+
3GHE@:00C$D8D!314$271D&3;%*<;0%D.&89"7%657'.D70A?3&C?G2:9;BC$6ADA<+$E!
@r4099
TTAATATTCNATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGT
+
1>E<5A2+,C%(=,FF&;!.9F43A8;:%@"%*@<'1.@&$?!+/
@r4100
TGCTGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGA
+
5D8A2'6,?+%<?/>*D3A3%9&:"A*2C0?%>G8=!)H9!*F'
@r4101
TNTCGAANTGGTGAGCAAAGATAAAAAATATGTTATCNGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGAGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACNCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCA
+
%%*"#'"&+$*$"'!$+"*'+))$)!+#$*+$!#&+++)+%)!%%*"!)&%+#&(++*"'+!$""&)"&"*&)!(#()("()"*$##)*!$(+#%!'#'))$%'!(+)!&(&!#+)#*++()*%(*#%$%+&'%*!'%#"!!%#'##"#&)!""'+#+))&)&&)$$)#!()&*(%++*)#%%('$%)!#'$!%$#"&**!%')'&')'!+$$&*&$*$%%!%#$#$(+)($"*(%"$&+&
@r4102
TGTGGGAGGCGAAAATTGGCGAACGTACGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTAT
+
%.?G+5;C/&@2A&A/;?,+=F7.C?D7%?#%D+.,A8FBE@3!@@"A>0;>)H!34G;1CC>8#
@r4103
GCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTTAAT
+
7-9A,-?:D-1D>>H(107D=3-@;("B!=-A&@4.C;"(E(?$!/%4@3:5@$:D09.E%'-H#=C,F2$,07G7%/.$4?)4'99HE?2/+F"4C*7A01!>>/49EH*
@r4104
ATTNATAAATATTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAA
+
50$CA6#B+0(0,//2'/:4?81HG2>)2;;:>@<,BB2E36A#6&E4C&1!%H*850?3+@8%6'G<?FH+-*E;/4.=E6%&<@@2)"0>=9-(EC.=+.(&9<0%&<0!B1
@r4105
GNNCGNATACGNATGCGGAGTNCTANNCTTGGAAATCAAACGCGCACTACTGGCTGGTTANCAACCTGTATCAGAACATGCGGG
+
&#*")")*)%'#(("$)#"*)$$*'!!)#+!(%#!)#'&'$!)(#"'%+#$*'"('(!))"%'!+$*!+(+'!#)''$#!"*!(
@r4106
CGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGNAAAGTGCNTATCA
+
68%:#E$;<&#6C5F8*0F"/DE:#)?-D;<C4HA01(5E:>C.DF3<4DH'-
@r4107
CACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCANCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCN
+
1G?H?.8E@9,'*9')EB53<$91'6!7"19?:FF)=BC,--%1@B2H+C,/;&)/&A2/(-(.;)1)E)7,+D1'9&&76B4*8*/(&)DCED3B-@$0+228;6<;A$>A9G#,431C<,8&!;18+9:#(3'0.EB%=%8HH*1$0G/*952:?H/)9>(#>$?E"@*99#5040,:>H@7)-D#3629
@r4108
GCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGANGCAGTCGAGTGCCTCATTGCGTCGCTTTCTGCTGTCCCACAATATNTTTT
+
;6?5(63(''C##%&+@%B+F!0CF4@D8,.9!G78&53@)/"&@F-HE+&9)F@6)7@%+/F.?$/;4&G(;34GH$7<D@9@-96'+<=B/41/$!@@1(."851/<36-)D/)7%$;=
@r4109
NATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTATTTCT
+
)6<>5>!(<CD/F*(./@&3./),A)E!:=)>9H=93#"21(E%C2$&)H(66:*.,A,BA)E!C
@r4110
GGANNAANNCGAGCNCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAANGCGACATCACTCCGGNTAACGATGAAACCATGCAGGAGATTA
+
#(*#&'*%(#)&$)!+*%$+$&(*#!"$""&%($())"&!#!(#+(&!(&!*"%($%)('""'&*!&&)+$)!")%$))%**(#+'+($'##*)&($$!'(
@r4111
CCNANACCGCTGNNNNGGATGATTTCACCCTCAGAGAGAGGCTGGTNACTATGCAAAAACAACTGGAAGGAACCCAGANGTATATTAATGAGCANTGCAGATAGAGTTGCCCATATCGATG
+
'(&'##%'$$#$%*"%'+')+*'(##$!'$+&%""*)'$'!+$&'('$#)'("%$%&'+)&&$+!()$*%*+%)#&+&*')%*%+%!*#$'%%+#'#'"+)##"+%!"(+#')+""$#%)#
@r4112
AAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTA
+
*&+'*%#(#&!'$"*('("&)*))%"'#*#$$&")(!(&"$"#+'")$&&(#!##(
@r4113
TGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGT
+
C8B8;$'>9*7)!&;C<@+AG:F+"7$FD3A%%79)&.DD
@r4114
GGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAA
+
D",09G,24'=,1#@>9E>9':%4<!D0E387@+6.4F*%*9.<+41++EE(;G>+F3&))/$-2*G6E87C
@r4115
GCCACAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCA
+
@F!(:8*>;B*+/D6?-3F4$#DG6,HAB%.?:122!/C5"&5>)31?86./84'C%!54-=/C4CE(E9B1#(E66,;&?4.080"B/DF4GG
@r4116
GGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACC
+
7#C95A#.+'*B#%+@4BF/46-<-60,4E,F/D,D8H)/?8/1+!<"20F"2+=D7DHA,D0F'E)?-.9AD
@r4117
NCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACNCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAG
+
0&@*/:30'H.G%D*1-+DGF*-6*;*196HF:;=.0B&('#6HH81>(C,BCEC-.7:**>/90*)"D70A+6F<;*>(,*
@r4118
NNNTCNNNTNNCNNANTAATAATGNNATNTTAGNNTANNATCATNNNNGNNANNACGAACTAGNN
+
!!#$$"!!""!$!$!!#$$#"$!#"#$!!##$"!##$$!!$"$!"!!!$!"#!$#!"##$"!"!!
@r4119
NGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATNTACC
+
-2)2?3C#9<+B4"2-.+,)H<1!90H$B/",&D$E-+4E50%,8552%66&:G-*8+(D-;AC/2GE&C2D4DA((#C+F1)+D6CA,11C?*<('+.-1(-'$393
@r4120
NCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATNCCGACGCCGNATCGCCCTGCTGCCCCCACTCATNTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAG
+
!2!E%"2@D3C#,"E:?G!<FF4%#98<6%H0*0@0((?976;F6D1#C?$0'$+6G*"393,G%B0FC).C->3E=*=-8D3#,+6HC%<<B)89E80+=>7-;CFH031=H#+C81=H=-?&.@9A/C(1!
@r4121
CCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTG
+
3%B#%-419-H3<H+/?H18B2("-B'+2+>63':.)90:'B7-&)>8'/:&"#0:=>?9;>E$FH=6,A#:=<.@)1D:GG/<2+@G33@&0!'#:'0;8(G9(B**7569".>=3!(5
@r4122
AAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTAC
+
0&9E<2"<"0GDB5G3,+D;(,!9H@.H)*36E9/',G>8F15.#D+,F?2<B*2-DB-A9"%:A3'8?+F9B9-=6,5<&H"BF$)'('C%,G)=&1
@r4123
ATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTNCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGA
+
<A>2*('?#'9&+.2CGC35-7"$3<+1E0'%),6<7)?1=?>!0#1&*,:E'$/(13<3?%BB2A'7D06?B$!!2D:3'%B)*3%6=8@B9:!%2$E0?F#D*7?>.=A=.&'$,3B8*H6>')#6,,AH.?&>?(G,H(:"-,F*.*1$#3H)>!9<G(%47'D>$(4-:#&",<7:9%
@r4124
TGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATT
+
$'"+)'"$")'%+"%&*")$))+)""$*%''(#&$+"'#'
@r4125
ACTGAATGAATGCACCCGTGCGGAGCAGTCGGCNAGCGTGGTGCTCTGGGAAATCGACCT
+
7"A@'?=-D@$?<&G!/0)@3HG.;?;1)>+?"-<(C1!+H"1H2:<=2=/=7$8@;6?#
@r4126
NTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGGACTATCCCCTTTCTCGTTGTGTCCGCATCCTCANGCG
+
!+$)!&!%#!"&#!!&"+&$&#)*#&*##"*#&%$%$!(&&(**+(&)*)&)*&*$")()!)+$"$"%*!'!+)+"'%(!$!!!'*($'$&+)"&#$&"(!(*!'+)&&##$&"$''%((!+!+$#)+(")$()')"$#(*"))$*(*!#$!$!+)%$
@r4127
TGTATCAGAACATGCGGGCCAATGCGCTTACTGNTGCGGAATTACGCCGTAAGG
+
@-%)9&*;*6/=4B6()5E&#%EE@DB@9:)%<-(;&/A(D=3""C06)-E9*A
@r4128
GGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCC
+
$+*&%)#&)%!$$%%$("*"'&+%++#")'!))"#!""&'(#&&%
@r4129
GTTACGNGCNCTATTGCTCCGTGTATTCACNCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATNTATCGACATAT
+
$&)$*%#)&")#)%*#*+&&'&+&&%*#"%*$"$$+&$!'&"+*##&*##'"+"+'$&&%$+%+$*%*!%""*"!")!')&!+"&$*+#%+()"##!("#!#'%#!$&)!&$&($'#&#(!#)!")+('&*%+$&%(*&)"*)!*)!"&$(#$%("*('+++(**!*&&")!
@r4130
TTGAACAAAACNTTTTCCCGATGGAATGGAAAGCATATATTGTTCCCTATTGAGGATATTTACTGGACTGAATTAGTCGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGT
+
-="?B0*-+B2@8'?%/.(,@?4:FE<G2472<>'$:0/1$>FD3=96,'@H#<C9'$&241&G#B;$G)GA;1B"1&3'22*;CA;G>7)?.1/2((4$=.H@4C?$-F@4%G+A-..)%<-!-(@?)6C?E:-E$!=*E.<:0*4.9<#&/A&57:A@-(+F$<'6>1<8&G40BF7#3=>;DG'+1+'-;
@r4131
NNGCTTTCCCTTTATTTCTGCTGNGGTAAGTCGCATAAAAANCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGCTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCNGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGTAANAACTCTGTCATTGCATGNGATCATTGGGTACTGTGGGTTTAGTGGTTGTNAAAACACCTGACCNCTATCCCTGATCAGTTTCTTGAAGGTAAACTCANCCCNCCCAAGTCTG
+
"!+#')'&&&%#!!%*"")!#%)$*$'')'"**%%'*!"#+'#((%!%('%!$!*$#*"+*%')#)"$+$$+*!%%&*&"#%"+")"&)"+**"$*&&'("!"&+&())+(*%%!&'!+*(#()!&*'%%%%+#(*#(&(&#++*+#!+"$!+#%'+#*$(%*$%!*+*#"(#+$+$*$"''&($#'#&)$%"%(&$"($!$"+%+(&"#+&*#$***)%*((%!#&!&*#'#*+'#&'*!'#('#)+$!!!"&((#$%'+!!&(**##"!)"'%''!+&(#+%"%++%%+!+)%*$)!!$'$!+&$("#(#*&+'*!''(()!&#+*(#!)
@r4132
GCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCA
+
*:=&$&9*81<0"5>!=?94'$%0!=G)C'=;?>?2.:5(5
@r4133
GAGCCANTGATGAGGGGAACCACCAAAGACGATGTTATNCATATGCATTTCATCGGCCGAACAACGGTGAAG
+
;F?5?5;8?+5/(@@-=15C!:-6%+&H93+%*3?GG'B+A0(4+B5&B3E!0'#A.,9>=E@8:8-BC%+6
@r4134
AAGCAGATTGCGGATATCAGACAGGTTGNAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGGACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGT
+
@?><7!C@>@F(!D)++1GG,:!(;E('A94+H<E91CF;"+'@0"BHF4HH7=<%#)6*CB83F<!"=/:(44?!;'C.&?#:2=E!,E+@H-3>.G;1C>GH+8(.(ACH:43@?)).%B1,3)F/"/A@2)"&2770<5F4<6#C800'$!A4/H<"6=B:B5-
@r4135
TGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGC
+
F):./;$4!88!+B'/9=%+8#06-@&74@<H!A@)5'D@6/;;.F<9@/3E*:E<C>+4(A*(F*&/
@r4136
CTGACATAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCATGGGCGACAGTATCAGCCGTATCCNATTC
+
09E'67!6$&":)?8=G:*.<)<!3/&>8A?,%7D1,4'=<=:*-84/8")7-EDD'.+H10-G5:C--D0!*0EC!>F#5++<>-6<!'<;.*/&->&D3&)
@r4137
GTTNATGGAGCGTGNGGAATGGGTAAAGGAAGCAGTAAGGANACCCCGCGCGGAGCGAAGGACAACCTGAA
+
!:(55/D57,>5.->!H?"$-?,(H*D)D0C"%'1&>E2AFF%@(@&<A=BBA=+D$F&-$CA""(2-/)+
@r4138
AACNCANANNAANAAGTTATGACGAAGAAGAACGCAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGT
+
(($%###)"#&%"*+'""!))#)#*$#!"%#*!+"(((%$$!(+'#("+)$*)$!$)#"(('$#'+#&$(#%$*!'!%%)$"('$%)()&(!")!%#%)&&*!+*#')+')+'#(&#
@r4139
TGACGCTTNCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTNCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGATGACNCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGA
+
ECF)A-8.@4C&'A#A?&6?H+HA"2+GA&8E1"<#<$=470?'&+;!7/D0C'2=#<52'=7($!GH#/@$0.!0+F$(40F2&:)9/?4F2<&C*!7A;))46</)D$*<<@'C-7BD3&D#<8,A2?87&-7H?,460D709D!>98D!.#.<@H?@(>
@r4140
GTTGTCATNTCTGGCTTGCACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGNATGTATGGCCATAAAAGG
+
0<.A46<A&%-@72E69=@!($,83B)%?D-95.;>,).4=@)CH!&D(BA*1E(,*?!&>83<C!&./B86F)6;1G+0/
@r4141
CCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGA
+
1;C/D:1:2D5"D>91&$@+;+?$G:?:?;D%40E=>,<=F.F/5)%?!%75"66B-21>H7G&""0EHA("22*4#+%
@r4142
CATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTT
+
,<&97*0@7*24CH!8>82<<159(F'.=5"!1$.C7F0:C=/;.)7,4H=";*>C==!GG!/
@r4143
TATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGNCACAGCCTGGGTGAAGGATACGTAAGCAGAAAAACTGTTCCGGATCCGNGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAACAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTNTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGNCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATG
+
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
@r4144
ATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCNTCGA
+
*8.=225DG9B#5>F7##3+)(H))"$H%!6H$@7$%*8D8DG'=?B
@r4145
CGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCCGNGCGTCCTGCT
+
394,5B,C12''0%4":*8331"<++56FAH9$-<>.&$7DE6@1?)A3@'9)*:2."?@C=(4G3/+G,<0'73B#A&B-',F?!8BH+6:)"E$E&E1G/!
@r4146
ANATCCTCGTTCTCNTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCANTTCCAGCCCAATCGATGGTGTTACCAATTCATGGANATGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCACACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATC
+
)*;3=@+!/4:FA4A,G8-)09>5B*@&F0328'*#"+#69=GH=F26/9@3<'"%A5,@=="$<-HD0;-.+C5<HA0'D@3E,(+*+,1@3!E")/A&-B?49=.A;;/5'9!7F1GB<*2F#5@520:!6<H4"'50!)*4/6='C)A,7?3$8-G'A(44*%D-.3D@3<3%/0;623+:HFC(1&,-<'51=:$,</768(G)+G(4&+#(&
@r4147
NCCCTGAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTA
+
5G.D927E78F09110/G8+9@02+8=(&8D/D<9$64<G8C>4/
@r4148
GANNTNCNTGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCACAGTAAATCCCATGACACAGACAGANTCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGNAGTCGTGCGGCTTCGTGGTAATCACGC
+
)'""'#+$$$"%**'"#&()"('!"#''&#$#$)''#&&*$+"'%!*'$('#$#'('&#*&##*##()(%+%"*+'")$#%&'%%$'%!%")(#"#''*!((*!!'!++(*+*%&'$$&$#!(!"%+)(!+'"+%*#*!(!%*&*#*$%('#")%+%)&&"))*+"&&*%&
@r4149
ANANNCCAAGGGTGGAATAAACCANTGNACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAAT
+
&$)%!))*+$'*$)+)#'%%#'$"'#)$)'!!!+'+"&("%(+%!$)#*")'*'$!(('*+%$")!#)#*''"&"++!#+)%&*&##"+%#%"(""+!#'!&"&)$(++!#"!
@r4150
TTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGNGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGAACGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGNG
+
@.%>.C:G).*!?BH?2G,,#F?9<H&"!>/C813*D:$.<>4H$,D07*H"&(!*1!9@&BD(;(H&G:2$53<:EBE=8=*/@;6'+<?@F$/48'6$-.7"+F.?+D)@2.$DF+8436;6,69E!)@3*2=;D,C;5
@r4151
ACAGCTATCTCGATGATGCATNAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATC
+
E/H<4@,F"40/.',)#E792&(6/?)?.#!%#;3:!&*/9?G#+G;*H)-86/HH1D6@+$
@r4152
CCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATT
+
%''8C:?;0B,/!8<-D+,'?:B#H'B"G#HF&73@+:/86B85G7;<&7#'(;E(&@E%0CD#@G?%050"G/3%B!($>8D9
@r4153
GCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTAC
+
*=;7><?'G-?75F8##004<EEB1@$4,-,!!D%<C#(;E'/<-=B&3>C20E-!
@r4154
NATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTT
+
!3>)-=5&#?G5")?<"F45;):;8?H1FE9;G?#0<&/.439D=!:5/F*F'63G'-&2E17>
@r4155
TTCAGTCTGCGTACTACTTCTGTCTGATTTCCGTATGCTTCA
+
2@915);1+,15%G2;+@%@*.$E5E.C@EC*'7*912>$*,
@r4156
ATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGNCGTCTGGCGAAGAGTGGTGATCAGTTCCTG
+
F4<;;.B?H.99C5/6<$C#"HF:/*=8<%'D?:)#)'!.A0C3FB0.2A-$H-;72;G/9=AG+:=,3C)
@r4157
GCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGNAAAAGTGCGGCAGAAGCGGCGGCAATACGTGNAAAAAATTCGGCAAAACGTGCAGAANATATAGCTTCACGGCTGTCGCGCTTGAGGTTGCGGACACAANGAGAAAGGGGATAGTGCAGCTCAGCAGTGNAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGA
+
+(!$)&*)+)!)#"&)(!*)"+%%*))%'*)!$($''&!*#!'*('+%!%!%%$'+(&((%#!!!#$&&)'%""+*$#((+!"!!'(&%)%$%'')+##(!*%**%(#%(()(*(!+!#%'&%"%%&"&!"&'*)%##!'*#%&)&%(+*#"(#)'(!&%*"$$*$&()""%&%+*)*('%++&'"#""(&#+"("&!(+)!')*&$($%(*'#(!)*$$"+'&!#(!('!('&"(&+*((*"+('"
@r4158
GCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACAC
+
146@!+:./$@<!F95B$8GB'142A:=9B-E-,4HF>8'H/!$(F29)3<,-<#'F.-
@r4159
GCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGNGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGNCCGCAGGCGGTTTCACATAAACCATTTTGCATCAGCGACCAATCACCACA
+
,)<+,G<65;B14*7/3*H7*-1*"8><!;2-5'6&0?,&#/8'EE5'@-&-"H>''*AB26@=.0'7A36/7A$&+)E0,553/'#D@"!;>&*C$=<1D4=:/EC<>!A9467A*D4<.$!(8A(D<;=;=@(@F%0>$-0):G+D&,7-C@8&58!.7&
@r4160
ATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCA
+
:,@'%6$>%20?B7#892*=C:E9-$<.($%/A"4?<5$'.+</.7&.=3%'$(3B*F!3*%&'%A&E6B
@r4161
TTCCTGGTATGNGGATTCTTTCGGGANATAGTAATTAGCATCCG
+
-2"-:")/7+=':=-8E&C+3>6%+7*20,/#"D??!/<0>F%B
@r4162
NAATGGTGTAGCAATAATTGCAANTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTATTAACNCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGC
+
!7F4/+8CC.,4:FG903>D4<B8>(54D';(=3,;&'A0B%%?;+F30!H'1.%#4!16>D0(H88FD691-G&&>)EC5*>!>!#0>$(6H,F**HE:<!B07,6BDD)B!'"-+B2!>(<D644.,4/#;3B;1<9'7742H&D>&C9A&8+5#A3.*?#410?37.<8+6A/5,4#F56$HH;DB'!H5<'&"(=BB73D!.49(72#>7&E=?>934$6
@r4163
AAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAA
+
0@%,36=@H22$?,)43-7)DGB"'?$H.0/>3<C?$?>BG+/;:HA&,=5E6/2"4$HC!*F%6EB>
@r4164
TGAACACACCNGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTT
+
3!3=7C&,>!*3/0>AG-B./F!D+=@+<0=35DF#$+@@5!)7G*-#6D7F4:@9(8
@r4165
ACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCAC
+
B6!-H,B$88<;:>%.=>-DG;!$7HH!(GAE?-+7C:B=A03C576&9,-(5'B&
@r4166
AANTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAAC
+
*""8?27:CBB*.<6/(8#FG/,"4(;C(@69D)04!2:85#;/H%;EH7%29;>0+77C#$BC1907%4$'=;3F5B-37;<C>3F:.$;B1)>&F8=(H'A*<9:9&$CG9F<<;!;#H9-E'ECD(<8>=8-B<##9)5B,'/-72$%)7=C+1*?='?9@.88AA22')>-#$9"E=A://!5(D2&A#.8DFC%;&8/.G-.+2<F=EGC(%@7)""9-8D9
@r4167
NTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCAC
+
"G./6&+D?86@/),"?B&.65$9&;G1-;.9(6:=E@:@29A0A;%>$("E9ED/8B=)+8C56:D,6
@r4168
GNGTTTCTGTTNTAACAACATTTTCTGCGCCGCCACAAAT
+
#&+"##!+*$&$)#*%'&+!$$)**('%")"+$#))&$&#
@r4169
CACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCNTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCANCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCC
+
6626G7&!0-DA'(3-@F5:#=+7G47+:"!26:6(:E:9(857?B/@&D"8E#/"!G>>HG9BD?50AHC-15DH:F;+%G+D*,/C54/<=9=!8:FC&G?D$6$3E*<4;20G-+(08D.%)@>@0D"F<,-1*F3D6"'%:?AA-H6?'?-@8A#D2?:/#9G!,=61:B=03B=,:FE):>1#B$-(6+2;,?&9&$;G8%D;#<2'$/H;,F)*@
@r4170
TCATCGAATAAAACTAATGACTTTTCGCTAACGACATCTA
+
DC751.4D':FA%"3D=?AC-(?'5<6$HG2"B)G%C4:6
@r4171
TCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTT
+
D;:-3//=)D"$4D08)2H<C;3%=++B(4&@5'.<A-CD-$6C'"5(":&.>:F,$G;!+?#(.@>6;+%H2C+*G90>."F'A56<@BFC.;!C7-7)-.
@r4172
CAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCNGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGA
+
-58*=)1"/!2(3G1H45*2BG<?=/111#*H3!@&A@:G7<%#7F+B/?#G,"EA+;A$'AD<*&(&!-$FC#E;1A%<D3-H!?9)!0=++D/6,/;0675E=DD6=$0&,256/G$3.!!9?;"4AF==1+G:;>9-&7"#7.'F*4#/6#*H,
@r4173
GANAGNCAGAACTCCCCGTATACAGNCAACGGATAACGGTAAGCAGAAAACCTATTT
+
#)!"(#+*""&"'*&'#'+&(%*++(!%"%!+$"!$)%'%($(&')&(!%)(($(+%
@r4174
GGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCAT
+
GA')8&$>G'A6F6"7B9';B8E*)2>3""+5.!=+.'.(+/HDD0A80FF&H
@r4175
GGGGTGCATNAANNNCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCAAGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCNGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTA
+
*)"#$)(*'!#*$""+&(++("##+&$)!#%#$#(($)*$%$%')#*)(&&()!""+!!&#*$(!+"(&!)$'++'(#+*&+$)*%"!)'+("+!"'$(*)$$%+)##++'(+($%!#%()*)"*)&*+*!(&(#%(#%+&(("#$#%%')#$"!!%!!!!&!&)%!&!''+'$)%%!'$!$*&+''!*("#("!&*(#$*"$&*)*"!*
@r4176
CGAGATGCCACGATGCCTCATCANTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGG
+
7%=H/:'$*BEA%;+6'@H8*->,,A>,'0>%=E@=8%D?.9"'.E1"C*4E--A,4+3@//1=E'8&)1?G$=6
@r4177
CTTACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAA
+
"'3%(8;*/<@G6#2(6C3+@8:E.@6G#$#GH(.6<,5F+DEC=F*?G,!+.#<7=C8"2&-6+&),A<F30:G84$40$9E@$.,14(G>B56'?>,>9!C,>8<%>E/(0'G*.=#-%C"4";E"6B.5%H'
@r4178
CGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTG
+
,B.BE70&G=DC<C/62B)ADH"(,H>9";0$(27"#<+,+04;41=)09BBB@#;CG*/$8$E=HH"/396,1D3$5)>@))3E43C!2H),<$#AD4C(/87',7<#=+-8?7AC3H=$*G98C4G1#9<!H/H)A4.G@$7"<?G,GE("D&4,,D!$"*D%<0"B(E!C5D@(7?>@")(FC)EDE7'FF4*B2C$"?A0D!>%:)84?HC8/#5)!'5
@r4179
CGTCACCACGTGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTG
+
B!:,G=6#&%2)4<(=*?,2<240+2$E<0DC02:<%+C7F7H?E2C?+H$@,5E%B;2G6+((F>;GD/8?.%DB/=/3!FC'857$.&3/)14H8;H<$2;&5"<E04@A-+>#'*,5&'-B55.3:6F$1@*:/5&2?-,7
@r4180
CCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCA
+
54"H;'-",F#=-5A5BBC3E=AG=<>>;A.F/?/>!FC<1(-.119(1":#!
@r4181
NAAGGAGGTCAGACCAGATTGAAACGATAAGAACGATAATGCAAACTACGCGGCCTCGTATCACA
+
)?,.3)-)'8!E@$#8)%:FC%)%GHF%5$)(A1(5(+'2&G3+*(7&61.E>F-/4B*!E(D->
@r4182
ATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGT
+
AG+)!*EH)+4(0EH'<%:+D+4>60EAH6*B=AD<8"(<&G$9%1.*;&:?C#F4D!/%1=E1=9D&-!:B#E55
@r4183
AACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCNTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAAC
+
<%4*;2-,C48,)/*80B%FA9!>F6-57C002?F2#%A>(,HB..7$3*9%&D6@;@B;G9B-.0A(+17<F1>><-%")1H*9;-#90=C-495A!65;@DD,3A*5#-/3H;DGBC$F01*D%E))#&?3H..(3C#5B+#E$>2,*@E60A@)2%F8%C./9%E0.-;-5
@r4184
CGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGG
+
/!E+B+BA.HGCB7G@2<-;0&&(*78+1!1@!74$(!>:B;#(8?$(%2A#@!*9,;$<0<@C?9>053$8/&?3$,<D<"7H;5EH1*+F.'
@r4185
NANTGNCGNACGNANANTNTTGGTGACTTTCACCGTGCGGGTGATCAC
+
"&#"$#$*!')$"&%$!!$+#!!($#+(*"++!&##')*'"&$")'(*
@r4186
TCAGATTTGATCACCAGTATGGTGGNCAGCNGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTAACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCA
+
H5,2;2C'F58E8.D"F3'>)!)HDGE)7-?2"+0G;%DA*G$E"=*(&<!8>!?/:$&D>$BF(1129*"EA7,*=A.AH&7';!'91C@>1>H$+4&8?E1-2.1G246>/?EGG6@C2B+4<(.&A*C(C%.$)5.1:'4(:&4D@"B+20+AE=*C=?7=!'<;7/H$
@r4187
CGTCTCCNCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGC
+
F@',!(,@D+8F>0*7)*)1;G2C=&F+&,/-('6@E<<5.1BED8$3,'2+%==&+=H;27E+17&<
@r4188
CACTAACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCNGCTGATCACCTCCTGCTCCGGATCGGCGTNACTGTTTCCGTTGACGAAGTTCACNGCATCCAGAAAACGGGCGTAAACCT
+
)+#**$'%%$()**$%&"##$%&(%*)!!''")%$+)%$*"#*#))&$*)*)&%(&&!!!!($$!+(%%*)"%$+%&)$"'(+""&(*"*""#"+++&&#*'*''*""'(*!!'$!!*$+#))
@r4189
GTTCGATTAACTGCCGCAGNAACTCTTCCAGGTCACCAGTGCAGTGC
+
E5D(8;G"<%2GE"2H?1"3@BC".+#84H4B;1115ABCD:C1#B%
@r4190
GCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCN
+
(*0A6G02;?=%80(!843*E/E<7=;#%>H-5:83C@*7<,64B9.$07F4/-B!&$,77.++(G/)!2G""G1"+!3>ADH='?:5*F(<E/.6C5,DE
@r4191
GCGGANATCTCGTTCNGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGNCGAAATCGAAT
+
A-1@=()D?DBDC9;12F*#'C/4E7B$!51+H9%F?8D(1FBG%G@!(1H73CB2*EC?:<'1(H:";+-.
@r4192
NGAAACCCGATCTACCCTGAAATTTTCCTCACCGATGGTCAGCGTGTCTNCACGCCGNA
+
$1><@D(%A'()":,5"7F!'"+A=8B:C(8#2%!5(!?57=)97F9+,HF,H-@%0=7
@r4193
NTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCA
+
!,C96G5+0%980E,@0F.C-&G!"%,+9?>#-B=20:B"2&,1#;E6:>6@8.>.6:;2D19%:/C:2%&0,*<H%
@r4194
TNNAGCACAACCNGCNCTGACNGGCCNCTATNNNNCGANNNCTTCTGGGNAATCGGCTGGGGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGTCTGTAGGGGTTGCCAT
+
*%$&&)$#*%("#&*#&!(')*)**'$$&&$%!#!''*$!(&&)%*%#&'%$"*('$&*'"+(!*&)$)&#''+"##+!*&'*#&'))("()%*#+%!(*#+$$%"'''$$$)"($(*%'"!#!!+#!*'
@r4195
TGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATT
+
?5$H($5#H"&GH$2:&!?-#-&9<*1?F(4B&%18?:?/D8=3621;#:?,&G4+)#A7
@r4196
GATGTTTGACATGGTGAAGACTATCNCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATAG
+
9/!F+H*A8"-C*/E!.0>!)'&=46:'C99<4&<%&BE"DE>7"8A2B%&9,C52($-9'&7,3A6)+0>#
@r4197
ATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCNGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACG
+
>4",C=:E'&6#87=AE)(#G$4":#G*,HA0B(!&+H=*)@><+B2G'A#7,&"7#,":!D/=BDA?<&A@9<!&8.*4124A:4;-1(0C)>G)EB9F8&678"#C1A4##'+*$9EC9!A@&(0C#!H+@-)7F;>=,H)$E7'+;1)GC!G(?47>896BC6!A+G*?:9+&%=26B'/20+?)F;.$1=:CG$A7?F<0FC/'67D+-$F*E03(%07EC=7)5!4-+7((-E>+?=*@H#0&>,
@r4198
CGGTGCAATGAAGTCAAGTTAGANCTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATC
+
##+G(#4,=9&=")4C7"$7+D*+:D06GC-6(5.D$$0+38B-7%*#3/>/@02)%(+<8D''H7+::$=>@(@B.G<:=F;*
@r4199
TAAANTNACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATCAAAAAACTACGTAGTGATGAAAACTTTTCAAATATGNAACTCATCAGCCCATTTNTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAA
+
0/B,@243'90G.G.,H%<1=FC*<B%2::8)6F/D%7C<6#H=4=#5-6-%B&$F6<+A&?6C??BH)55.EBG;43+&F371)3'D9D1B%<15-8F>D,4,0C3A348)#4@'EC@@86#868@13*-#/?HD)G@+FEB"5B2/',4H#./H,6$H#*7?*:%*D.925!DE0=6E:8/E;:$=&G=4?!@B/*)@EG2#@,>D'.*B!&8;'&+)E3<!8$9H*,"+%EG":@#+<9?F3#%2/*
@r4200
ACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTA
+
/(#3=::(29$D,G(1#=<B)2H?642D4:&G8>B&#1/4438<0=CH9$"(*;8(G-:3,8F9BGGE;B+//D@4=A*(.)*,&6;2/>;*'$.=$C6)
@r4201
ACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATC
+
?"*!4&D&%/"*&@"6*95E&F=<D>@&""=C7862+452!4$;@/H2"9>5(:3(4)8+03F7>-
@r4202
AAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGNATCAAC
+
D!3>5B$;H/&7+0:7"+0*:12!</')+9!7+G2#7;GH39"%>D871G&-@,;,05;>"B3./D>!033H#22-!3>A*F@<88@;'+HH:5:.AG1A;GFD&5">ABG5:,D249!33$">=%>?G$/GHH"3?.'?%0A5
@r4203
CNGNNANANANANNGNAGNTNATNTNNNGTTNCNGNGNNNACNGGNCACCGNNNGAANNNNATCNGC
+
#!$!!!""!$!$$#"$#""$$$!$$"$$$"#$#$"##"#!#$!#$"#!$$!!!!#!#"$!!$$$!$#
@r4204
TCTTTCTCTGATGAAGGCGTTTACGGCTTNTTGGGCTTGTTTAATCCAGTAACTGCGGGGC
+
AC*H%F-4.3A>*3*6'#!&!716BB92.%AA32D-(:H1<2EB<AH;?E:8DF$E"<42C
@r4205
NNGGANCNCNNCNGNGGCACCTCAACTCCGATTTAATGAGCG
+
)#"%)%&'$$$%''!%+$$&#""!*##("+("($('&$%+%!
@r4206
TGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTNCTC
+
6*4A:C%A6BB*@!08.%(C%A0H+7#F%G(0!FG;0(A-:G>!?8#
@r4207
AAAACAGTACNAGAACGACGCCAGAACCCTGTNTGAATTCACTTCCGGCGTGAATGTTACTGAAT
+
2C+$23E8>>/@.D53+&0#GB0=/=-D+,27.H$<;F!:C?:HC=46HH!;EF7+A-/=(H?>?
@r4208
CCTGAAGATGAGGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAAC
+
H%D60*-.1(1?7A/:87A@,#'D#!350!3F.$429-"@B7,6&5F#*81,B6#$A217/:==0=G=3EG2"*$=$F;06,/3?G,E873&,9%D;-"7A29'12%$.<)!44=44%A?E9,,8=(EG)6;B%>>6'(8?$-+<4!21(2-4F+(90.5B*>1B)42@28F&C@<
@r4209
CACCAAATGCTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCT
+
(%H-4E<D;)*F2"&6*#=8(&8GA@B#.>.=A/+%%,>,>50:&>$,*&#+9>6GA1/+,&C<5(8<+,&?E(>B,A-H):-;(CC?58H4FD
@r4210
CGGTGATGGTGTGTCCGTGTGAACCNATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTA
+
556*CE<G;"2$F@63+"%C.C24&4*(-@D)#'7&7CE,!<:9'"%8'H6%'H0?E<4!D)-5%':8?;44@9DC5F7F8=A.GE@<%"/+
@r4211
NNANNNNNNAGNCNNTCNATGNANNANNAGNCNGCNATNTGCAGTNCNNANCGGNGCGGNANNCNGNTNGNCNGNCAAAANTNTCNNTANNNTCGNTNNNGTTNTTNGCNGATATGCNGGNGNCNNAACCGTNNNAGGGAATGGAATCGGNNCGNACNGNANCGNNNNCNTGGNCNGAGNTNAATNCNANTNNGCNNNTNAACNG
+
"!$!""""!$!!###$$"#$$"$!##"$""#"#!"#"""!$!##!#$#"!!$$$$$"#"!$!##!##!!$!#""$#$"#$!"!#"!#!"!#"#"$##""!$"$#!"!$####""!$#!#""$!"#!""$!"#!"#$$"$$#""#"$"##!!"!$#$"$"##"$"#$!#"#"#$"####""$##$!$$#"""#!$$#!!!!$##$!
@r4212
CTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGA
+
+#+)"#!%"##!"'()%&!"(#'&&*(+#"*&)*#&"##)$'"*%"&$$(+$$(%*(#*))&!&&'!&!"&*(&)'+&
@r4213
NCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTANGCAGCCGTCACTTAGAAGTGA
+
-.,!B,+3>*-8$9F;#(!G=);2/;?5=;".9&$.-87286HE9&/HG("*.6=DFA0,<DCG?2+$,
@r4214
GCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGC
+
C;AEGE8310$?9B:4%:5,6&%=G#5:5*C5HG+$B8)-"B0"F8C.F?;0&,F;=76"#%:2*@6%"(@55;C=:3D*4$,4A+7=(*#+90
@r4215
CGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCNGTGGTGAAGGGANAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCNCATTTGCCGCC
+
:=;2D5EE$4)D*;'77!*>%41!$2'&-6&1,0H/DG6@>A)=AC&/C%1H,83A9!:$1$+H30+A2%.96/=8?#AAG&*<D=B@.,=*02?:+&+DE'./-54-89&HF@))</F90,&0++2B'A6+4D>"
@r4216
TAAATAACCCCGCTCTTANACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGANTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGG
+
H??C0CH3(0+=@?B;",()?F>@>9$+G(B-'"9<1BB6'*3=&:HHC-&*?D6:HB@?*$GD8EC1.?$D-:#G/,.3//>=.4G@E:EH=;C*::!0@%"?C#D8&@.D%B*.9G:(:?!;=!G256/CCB0D.?/F;B9,'5C?92-&AH3-D8$(A2;>HG;72B=0-H78/%,,@.-"F5)&.(1E2(5=9%BD@=:<%$7=3,C1H64<;2B1D>@>*7C#-+?:)"<&'C?)!);'F*++%4$!)$3%-,-G=)HH"E**2>9+-4,&<H+:)57A#6*&45?&B9(%91D&<@$%=@'3HHC<>3FC4>"5D%4.05#<G7@5
@r4217
GCCACCCTTGCAGCATGGNGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATNCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGNGCAGAAGCTGGCACCGAAAG
+
;%EE'HEB.C6-4,5"*H:C+CHF,4&2?7"*$0:;9%/4++ED"5;*G:6!B&@23&,D(9'*!@4D0!4,2%)A/FA=H:'(E,:5,A9$'9?::H*<+-F,C>E&5*'$A@C
@r4218
AATTGCCATCCCAACAGCATTACATANTGATGCTCTCGGAATATCAATGAANNAAACACT
+
D)8?*B2;/'EB6@<068)&6+!'>$D&,,4AFB=2!#<)!/-*,9<4?E*4>CED9@5%
@r4219
GGGCCGTGGCAGTCGCNTCCCAAACGGANGTTACGTCATAAAGCCATGATTCAGTGTGCCCG
+
E>,B(E,*44-6%8)B?,A,@+2;27?2E'2:)*64A#941+DH="/7;<DA,:1;@4-0+?
@r4220
AACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACNCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGTGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAAACCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCCAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCNGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGG
+
C7.;E$9:<$C2561>E3(".%!(D$$:6H#.8-7%%?7+H(+"0=8A!G$288-,*A(/<7-F),**H2#A5&'?E,@DD6+HA.8>?</BAF?8??E6<CC)'@/A78/C3>=5/&9#(@827@=3G1>B>4"/D>(((30F9B7-515%BF7A7:)50*;-#*.04!-F:@D&;-)F%<*>4>E,%B#8(,;:5-B"5+;3832=/,?3:013E/#.)2'1=66",;!95=!F%B4/*2+<@1!&>1?C7/?$22D.!*+B<0G:%5B5/F1H.F1A#'-+>@63D<0!7!<19*0B00#52@DDA"07/&<212*H!C3,7?(759(,!.G86H$2+620*#D?=++-0G(G8=.%36>*#'!!H
@r4221
TTATCTCCGCTCTGGTTATCTGCATCGTCGTCTGCCTGTCANGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGANCTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGNTGCGTCAG
+
=HE87:B'6F)!B$%:9C#1G%-1/&!81=$)8H*;8(9?*"6AHDB046*/3D(""=8>B*)+D;E,4(/&-<E4B+1<!8-DB$9@>"&>,@1EG4!&)HD5HB6>+%-C/)C((5#%5*/C@0G#H*;E:7AE:67=2D(C2#D"82:9?F-
@r4222
GCTCATAACGGTACTTCACGTTAATCNCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGAAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCCTCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACA
+
'80&B13B()-=9+7+)$4F(07*D.+#H.?A%D&4)*/B,,01@CD>4C#B#A/:'"//H2$?A&32'15$BD4)8/&37"&=<):4&#,'%"';?;>E-?+,!";#)FA)G@5'@?:-D1>)#*+&.$'D/A:B768!8-??&-<1"!F;;61E"?8+772G>CG6>-@3D6&H&&;D:-)'#13@G3#)H0,,D&F-;2%B%,3*61>??,/H5<<<&A2*6G"=56E118#3/A9$618:*50E.)>*;"5>
@r4223
TGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTATTTATGNTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTAC
+
/D=<36C'G@,1%')2/%?#030)<&=GD2*F'B.F.'F/?3!G7$"/+G3;B4?8,B1,A??'(9#@#D9$6*DA%A9?&C@1G36"=3?D*<.5+,H.=>#:(3!GEC9)>C(B"--@)DG'8D4/51HH#>E./%9E8,08053'4!E"&?.(6E>FG61.@4$'G:=36
@r4224
GCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTA
+
#7GDE?%<-6C4F+5B(,&#D1&))B5(D9:89G6#?:1H"AC9;4D<:(6G?=6/"/"#?7@0F:@8*7B!?;;+(521C;;-!H)?,$"28?E1)EB/<7)>%3-$)G"#DF=.@B4@E%1C8>!2#4$.G:2>:'29-'A.*@9&1>G?+#H2$@&>H@?1.5F#:A8<"3&F-=<@EAA=H@#"#<E$&D6&&85#E$6@7#6!(CC:D
@r4225
GCAGGCCTACNTTACCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTNACACTTATGAAAAATGGCT
+
#%%$)$&*+!*%$!'#((*#+*+%##')"%+++++*"$%')&"(++'#$%'&)!*)+!*+("$"!#$'$!!($(("#)$+'
@r4226
CNGTTGTNTTACCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGANAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGC
+
*&%*%%&&&"$+"*)+%$(+)('(%%)'$#'#**)%&)%%*%(&!&#&$++*%*#"'$&$!!#!'(+(*%%!#%(+&)%%&$##"+('#)&"*$+%)'"()#"+*#)#!%($$*&"")#)'*''*+#"%%
@r4227
NAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTNCCATTCAGAACTGGCAGGA
+
&==C?G?6EFG/D?D%C3?);4&H%D/?C%0)=5A9-.!.++&?6H=1/)D$C"7G
@r4228
TATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTNGCCGGACAGGAGCGTA
+
/1=;G*.F7-+7:6D>.E-G)*GA?,4%,1EC&(<E.<B=#8B>(!&H6"B#<5'B(/>.?"
@r4229
ACTGGCTTTCCAANCTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGA
+
.$8/EA'9#DD;-".)27!<*,<*:$CF4E2%B>DEE#)&C9G,B?%*"5655+G&C#%'#F)+%;=F*#(</)ED<'+(C9E'3;+(<D@(":<<<!E:6E+6%+4>CF4""65>"
@r4230
GTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGG
+
.H"8"#:@93>*C%#<;8F:.4+AB'AC#0E>"EH,,!!C
@r4231
NAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGGAAGAGTGCGCAAAACGCGGTGACGACTATCAG
+
&'@F0"*0B1B@-&<#0)70(-'3":,G;585)58@"-!7B0B"93!5+E#:/8#3BE8$.?H02428D81?*&2C@$
@r4232
TGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAG
+
,'!D;'C!G%$'&.+/G76"B9#!!9,%H&:CD?'$(HC,/B817)E
@r4233
ACGGGATCGTGAAAGAAATCAAAGGCGCGCACACGTTCATNTTTGGTNATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAA
+
565"4;,0"?3)",<B$,?)AG:1E$E</*C??>+7G>,0?B00/>,9E<&(F;4)+?+D5$"!162@+D-19G1-1A!-++"#?B
@r4234
TGAAGCCAAGTTAGAACTNGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGT
+
86,0HF!4@>::/<!!#0/2D<!=G8(D*GB.$#0+1.'@,/42,4@2!2<7!33H??'H=+0;8*"7@%=57;5="G('>(&A8&
@r4235
TTACCGATATTGCTGACCCAGCCACAGAACACATCGACCNTGCCGTTCGGGAAGCGGATTTTATA
+
6>>GG7(4A$@<!A&-.A.&*;&($;.C':@"1A77.0A/6'0(+9#A7BF#@7"@@7,&%ABF(
@r4236
TTGCTATTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTANATCGCTTATA
+
.C:D/0(#7,%)B>9$+D';G,!/3?+#/,5D<'4,5?F=>#/D2>6:8)H&>!#A:<H4FA1:"#B+(/#//*,<@?*.=)&H
@r4237
TCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTT
+
C*E2.'&0F;4FH37B8/F2>?>!>'B5":54>&2<610.)<F=5/;;<)#'C$5EBCHF:1,3!*8E*&1A3FDA()1%A-/,D$EH=)G/)7"E=3962<1,8$:9>=%3
@r4238
ATCTTCTTTACCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAATATACATCATTGATTACGACTGNCAAGCATCAATAGAAATTGAAATCGNCCATGACGTAATGACAGAGGAAAAACTTCACC
+
$&+%"++"%%#!()+'$('+)#'&"!$+"%*+#"%!!$%&&!!%)!"((!$+(*"$)''"""#)+$"**$!+#&!!"&&%++($+%++*#(*#$%*"##)&%)$"*""+%+%)$"&!)%)($)&(('&(**))#!$%"$)$$%)%(%!#!*#
@r4239
GTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGCAAAATGTGCTGA
+
A1+>C0,EC2G,!E"*?;+#;=-4F-$E7+*>%(!'78(,/&E2D'>H=$$G/B,D0A9<"!-.5%$$8(,$$:%+*9%3/42%B>)"*A-,<DDH6)/!C93G)')!"=;61&,."84/$H7)7'4&3>>)"E$DG.?&&6E=<$'9BEH,D::1
@r4240
AATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCACACGCTGACGGTTTCTAANGTGTACGGTATGGTCACCGGNATGGCGGAAGATATGCAGAGTCTNGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGC
+
,-&4*/-82*E,E(:F(@B+%2+<3$29E,A@=;19,>'>F@@E15?%3"=H:?A)%>$;81*&B7&*=7+7+?3;.!%&;*-1;6@+.BGA63<5+,@137"086F:BA/E/(26D:D"?+>-=";+#C@:955@$-!8,E'3>'?:58=%2H@B$)3'H)".=-5!&HE$.65H387F+AHC,G<<#5!!.";G4'*@H;'*8,'7-)>H%*$(*C9:5:C+4@9<D&6:?472,#.-%!!$04#-G6H%32&)"-<E)8%<@$36G;
@r4241
TAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGT
+
E7A>B$(:?<91<1FE:'@%>/';F%<"05?*C@?=+:?&0@BE21/(+8#?;#95%/>1&%++"2.:D!H)=H65"256C!)F(.4;<H363</.H24&E9+@98=34#B!H&'#9;$34
@r4242
ATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTT
+
7;E:>,!8:,41@<$)95?$'05=G1@4$1+DA+3'AB8*!
@r4243
NGTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCG
+
'")'!")*'&#%($+'+(&"*%&!%#(#&)*!!%"'&$*)*$!"&"+)+"%'$%$)')$$#"
@r4244
ACTGCTTAATGACATNCCTTTCCCGATTANAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAA
+
6"D0010%77>E%;>:7?7?<5@39&;,!!'E@F22*G5#4.G/1C72/9F75+43)>+!:#;F4BC+.5F&).H52B:''-)7H,>$:=5,5H9%G&
@r4245
TAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAANACTCGCGAAGGCAGAGAAATCACGGGGCCG
+
"$@</#1+-A>*!*=0:+!*E%#4.;32"%?:0/E8*$F#(<.<0%<*1.'=>?16+0)F99C8-C19-'&"2/-H"'2):E(5'*)(
@r4246
AGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAA
+
C5'B1+&9/F8''%'C?7**&'7<GE>F0:5G<BE+29BG5@C@D,&*75'09DG48G76!=H.A6A!A.%"HA<H6,&)=3++3*D#B
@r4247
CCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATC
+
-'">"$6;"=>"7''*/!3%CH7B=;%=96'GD8%,6H*-F18%<?42DB(BE#"2#/:<8,<7A->"=ED(/H-764BE1E/A3*=E?.;-$('"3>$3=)G<=>:+C6+G'/$?@
@r4248
NCAGGTCTNGTGANGGCGTCTTCCACAGTAAACTTCCGGTTGCTTTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCNGGGCGAGATGCTCAANGCGCTGCAGGGCTGACAGTTCAGAAAGT
+
"&)*%%#)((()'+%#'")!+#&+'(%&'++")($$'+#*+*%!$($!$"+!'&%(+$!#$%'#*$&'$$&+!!$'%"'#%"*'%)$"(%)'#$")+'&!#))+&!*&'+!!+%'&+'++)*'
@r4249
AAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGACTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGNCAG
+
):;)*5H2"4(;;9(,/G#"(1F?8'>)06)+.<G3400<;A=##%#E"H@.1C0495)9$7=?3C'G7?.,8CA88G9-4,@%D":?8@(A@'1+0&.4=7D8EB!(?61+50GA,!3/=78.A8(:('BF""4')5H148'A)-.H>
@r4250
ATCCTCACAGATAAAAAATCGCCCTCACACTGNAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTC
+
3&D=1F9&'4)9?!)C2>:@B)12224>"5@423HA14+9-))/2/H8&:4(.D&-,089"!-4FGA$
@r4251
AGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAG
+
A.B6DD'$,=F5%E0/E@67&H58DE>6@93519D(,'D@%(648,234!%*34>:'()'!3210
@r4252
CATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCANTGACC
+
2!)<9)4.*'8.&&;:FD)2--0E!828<$/=9<61+->9"&4$?:0:$B5?!(;%C<39$3C=)@>(
@r4253
CGGGATCGGCGCACCTTGTGCTGTNTTGGTTCATCAGTGCCGA
+
=:<&1%)GD?)9.,G:62..)4%A#6>C7@"23!-&.")AE81
@r4254
CCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTA
+
%G&H6*1;;*8@3<8#.5$,@07:<9',@4)G'1-.3#1*1DBD1(E6'/.06$?"?1E=$=
@r4255
ACAATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGTTTCACTCGAGGCGTTTTTCGTTACGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGNTGGCCTGTTGCTGGCTGCCCT
+
#('+BC6)-9@BH:C:DF'2"2F2:>#G?7$14,0,6C:!!578"741>#/@:9@A)D:2)=1'28C,3<D*AF7?4/?$/-%&3A$@+88G:**H3F>:;*."B42C$8/4F4?)=,<2)(6$G/#;E4C0
@r4256
NCGCNACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGG
+
%#%#$)(+&&"+#'&*(*!(##)"&""$*#+&)$%&#(&%%"!+*)+$&
@r4257
TTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCT
+
=#B;(DH7CH=8D.*'E-)'B306?H4?!,1(B=#H81F>E?2?6G+H#3;:'9!?;:'3;-7H/*/G8=4=,58EB88=$&:$"E/#B5'!7AF.2=-?=<>79DE#GA4C.2%/<3#=&*)0-&',*B$*??#3/!*''H2B2$=2)B>%*>D)$-C$0&;8?8;8H84"3G#3+40?B"%3G"*;H;<9D*+49+!;+>?
@r4258
CGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGNAAGGACAACCNGCGCANTACNCAGCTTGATTACGGGCAAATCCCCCCGG
+
D(CB;#-7:1B-4B5=@)A;8(@$!#(776<A3&+>#0$9BF3EE'+@*"H><<.;!F#)*D3D81<@$HC82!"5+;A,':8E&0%2E3!:D<$)35%0:5!,&@;
@r4259
TGGGACGTCCGTCGATGGCAGAAGANCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCANAGC
+
)@%"=+?5321<A$#1D5#+:=+F("1G:$!A<F%7',7D,7.B>G:A,&.;('F9H;-932"*F+-D<,1?-:1811-/E!#>EG:F-88,?!%1;%
@r4260
GTNGANANCTNAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGCTCGGACTNAAAGGAGCAAGTGTATGA
+
*(!")!%%&()")%%$+#'+('#%'($$$&+#%*+'"%!+*%)*&"()+('!#*+*(%)&"&)##")('+'))%)%"#!')!+
@r4261
ATACACAATGGTCGGGTCAATCCCGCCANTATCCCAGCAGATACGGGA
+
+$)!''')("$*!&&+"$&'()&("*"(*!+"!#'%$%%*$+''!#+&
@r4262
TCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTNTTCCTGACGGGCGATATA
+
@:-#6<!=C>+&6B")#4,%8A)?E0$85C%F/-*71E86=,1=A3$:.B*FD/,A!%A(42B%B=,#B5$54<&)
@r4263
NTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCNTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGANGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTNGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACANGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGNCTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGNTT
+
$C/&*'='9F0557#84&H)H0#A70+!08#+4@(BCHC=/>0+!%B+F$:1+GF@:<<1BC91:<$+!C*;*'0?%@(%92H3#7$)3"&1B4*<@A;C#%(C0(-B*2;0B'/=%<<(00A@&3G!AE8$H*6((3GA46D1AA><7$<=27B:%;7C"911.92G<2)E:9';?<>-*/62>-B&<8>7HEC@"(D;-*(!)$3B((82%G'>*6B"4D!0&#276&?!=5?6C',?;C6=/7-6&62+<%A*E2E'G8*/@#E/AFF.<>&<79+=110$/%#,8!<G36G."04D#;B3&1*(4(7"(<<6*4'B.8+!9:7GC$94%*$>A2AA#,-;&>:5!F/7-A7F#&D$-#<==@E30)&$!-7+<@:B)77ABF/=%C5FA;$!)6B(:/*
@r4264
TCCAAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACT
+
*)!'&+*%&''')$+#&"%'')!%#(!%*'*'(*%*+'%)#%*(+%!()')"!!*'%#$'%**"(")$%%*$)$)$(&(""!+"+*!!&!'+"#)!%+%)('!##(+"+'('$+)(#*+*'#((%#+**
@r4265
TNCGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACANTGC
+
'%:B*,C99')1=:F#./%8/=4F@1:(3HB,);H<:"+2B#%3F2!,*7
@r4266
AAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCNATTGG
+
.&#45,6CD+=&*B5#A($C)!73/#EH%:A"&5G!<D@:59$+.(85"0=,A'5D:56$ED@:4(?)1?$//F,G8!:H)*2D*<:3D@EB/?EB
@r4267
NNATCTNACGAAACAGTAAGCTAATACTCAACCCGATGTNTGAGTACG
+
%&$$$$%*'+'&&*!%"($*"(""("!%%#+(+$!((#+""#+&+!"*
@r4268
TTTGCCGGGTCAATAAATGCGATACGATTTGCGGCAACCAGAAACTGGCTCAGTTTGCC
+
+$!#+$"&**('#(#%')*#$'$(%*+""*%'##%('!&*(#+#%$'$#"&#(&+(&##
@r4269
GCANACCATTTAACACACGGGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAA
+
&(#(%#&'$$'%"*+$$*'"!&)%###*!+$&''"#&)""%**))+#*#*++#+(&%!%#
@r4270
TGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTT
+
<:/0G2&+&.8)E7;#.A@G8"+E%"778A@#;(6!@+$)*4H.3@==&D++0'/-A
@r4271
GNAAGTGNCNTGTCGGNAAGCATAAGCACACAGAATATGAAGCCC
+
#*'(!("'&"*$+$)"++)$%"%++*)%"#*'(&!)"$)%"&$*&
@r4272
ATCGACTGCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATNATNGGCCGCCACGACGATGAACAGACG
+
<&G57'05=?491E2E&<.3E)+D3GDAD1?:4#!<5"E2E)4B?=:?E8G'8BD1):)!28254=!8'9:=8>#$$.'@$F=9A,?A*D1%,$FC4;.A;F$D2!25;0'*#F
@r4273
NACCNGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCC
+
%*%*!%*+%!''%%%(!('+#+")&"$&%(&$"*+#!#$$#$"!%'"&&&)+""!!)*)(!*(*&&++#&+$("")%#%#+##*)(&$*&"""'%'&+'!#)!(&+!$%%#+)!")$+"!$&%+$$#!%!''#!"'*!&(&#&$)($$'))&*!#'(#$!
@r4274
GCTCTNCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTT
+
A?@F"/D>>7H.C9(!&F$&5)(0:0=G/#==5H/=")7B6>0
@r4275
CGTTGACGAAGTTCACCGCATCCAGAAAACGGGCTTAAACCTTACGCNGGACCACCGTTCCGCC
+
3>5E#,@/&+.*(7H'.0&.:F),6F'&.6&!"G1;+?';:?E/"A4,,2B@B+HE%,1;!@=G
@r4276
TCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCNCGATCATCCCANTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCNTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGANGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCTGCGGGTCTGGTCATCNAACCCTTTCGTTGCGGCCTCGTTNGCCGCCTGCAATGCCCCGGCTTCNTCG
+
349./40:#AGH!-&'4,*B5D'A$(=(#549GB87*'0*54FA.+D>*=2$@:6GCA:<0.)8@D?4;AHE9E1=@G4<F$+E+6"G?6,"H)#;&#2H+@*/09-1CF/'5+A5FB39=:!8(:F04C$B0E#D-=HF$:0':(D#9"G9,=&303)99'=D345+&-;86C&)H,'2-/BG"04=+).4ED29E5:1A!C;26F2#2F"4F:C7%,>35"!21$.-E3;>;(73>&B&(#'3(*21B8/$>->(3D>E+<4B2%H+")>7/%0B!#8+=C$E1%4%D"0/.,H*&",?'F5,"!1'G2.1!/E.#@D<A;#H)!@7A5!3&469"B(1("/<:83C>-!A8
@r4277
CCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGNTGGTAACCAGCCAGTAGTGCG
+
9E0+<(H<.7"-#G431'&;G1@(G!D:4**A<B?--"&#HF6*31:((&#D">8;=,--"!!,7CE')0,1(/+"!51;+DH:HG$FF851>,A$7>"0@G%.*9B=.<6;+;C86".)GA&@BH%=6B8"?(-$&A##D)8)>EFA(2)7E$C@+#B)#"*
@r4278
AGATTACGCANCTCTGCTGTCACTCTTCTCCTCCTCTGTTNATTGTCGCAGCCCGGATTCAAATGCTGCNGCCGCGCAGGCGG
+
@4!(+63%42!##@31-48(F9C/F2F+/&:;D$5B1AE3!E5/'#<4*+#!?292;38*7.</>0*-@%#0)ECA?3,.DB(
@r4279
TGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACT
+
90=>C&B"%=7#;<6B,=@<:,&A,!7,*$>:&:44,+>17=6A#:5/>?71'E!H@3$=57'<?:?'/DF"95$F#+9:C,4))#G/EG"5";"09+:6#10-%(=-
@r4280
CTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCG
+
&9G8/13</C(6EE9A!"4//C:E?FC/0(.=/83C6F,H%,:!/@GC)AG$B"A>&'?<*0<DD*B&DGA
@r4281
NTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCNGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTG
+
!/;;HD3B7/+637##3<496$:%.E*7/9?*$648</EDH7!G/7*%+1A>-/"H<*+./(<%'@$?;15#F=!D6(-H?F==*)*'<'5"8;/5/@G!7):7E;%+?+>95/F:F(6'9B36
@r4282
GCCCAGATATTGCTGCAACNGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCG
+
CDD)B8?+=@'0,?7'?6$5FFH"+?))H-HBD+%*;+=/$;8AB176=A/7!G>,<A.AEC&1FC#H=:/H+H*2&!G@=%&@:-#>-5=107.;6E)B#D3%6#<EF&#&H9F52&#8)3E7*FD.4H/%/9!;/%'80.'
@r4283
AACTGCAGTGCAGGTCAGTTGCTTGCCNGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACANGCTCCATCGGCGTCATGA
+
+*)$&&'#!("#$!)())+$&*#!$(#*'*!"!%'!*)+!&"#('&%#&'%)(%)'+(*#%$"+*%(*&!)+&)#%&'($($)#*''#
@r4284
ACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTG
+
*>3F'G1)/*28);E':=.:FC?6E!)-&7G5G&$!GD3"&>*11!;F8''-:$<B"6H'=8F":5+:.>'#13:&.(&(00+:;%*'44EH#2);11C<,G/6B&/53<)6#+50G:!?F;B2)H/+0:.-:A,H<
@r4285
GGTTCTGGCTTTTCGGGANAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAAC
+
=3!F)95)ECCE4;2G5F1))>1A87C.30*H;C7+%=A1191@";"0+;C@>>F>>=/<9'?8C>*(?2D08'=/+?31*A:";?)02'F-D3A53,0$->/B=G&H4><>:$<2+(&H-3&(:;'BC,H0C7H:+;>4;&3/0@89$"H-&H,/E
@r4286
CTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTTATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTAT
+
C,*75+/2C?2:"+)2//3B@!)HC('2,H75@181-3<4.!&!B6A-D934<F%%2)@3*,G3(+*$;%&HED#9H>@F855)(5#?A444@G&(&))EE66!'B*>:?+H7*BB+#"B"G)G!?$H)7-2B"E?;";+H@(?43&&:?DF1,(.?2;F3F8"2*%#5)7=/1C4.9(<,,19+7"'60C$9A"6",*'#%695,4?4+E9/02*$)B8>%B82=,E4>>-F$*'4F2,,:9)?.A>.(F1H=(2.47/E$))8:"'<C*'!/D:+3-CB&!E08+4'%4*3C9;A"#(6!1H,"2
@r4287
CCCCGCCTTAACCANCGCGCTGAGTGACTCGCTGGTCTGGTTNNACGTCAGCCCTGCCGCGTGCCCGGCTCTGGANA
+
+#"!)*((%+(()((%')""%*&"*$##%&+$&(&)%+(&)#')#&)(#*%''%(()$'!$+*+#!$($%%')##%*
@r4288
TTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGC
+
8.5;@=<4/F-7HH:4=@2,55$9(3!52),+<54(H9,&%9/&/A,.A9G)7,'+F9H?:-,BC-%F<,%:BHA,=/-
@r4289
AGNGACGACCACTGCCTGGGACGAAAGTGCAATGCGGAATAC
+
!%("D2,08C@<0:$:'5+E*F0:E(3D+C=>99):):.-D:
@r4290
TGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACCAGGCATCTGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGNTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCC
+
$ABB>)/9.776%=+=#"70-;?589<F6ACG(<43FHC1A.!B)<%$C<%D:#?(;9<2%2$<#?6>-@;:%5'!*(D8&&3CEAB6GF%F*0%9$0=/6#>.!=F2HH+?5=E#18!695;&'+E>D$1H'"':9$C$H/$H"2*F$.<(=0-.(9&A)3GC79$/8<:&;8?)4+5;&3FCAF>=((D"="
@r4291
NTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTC
+
#D@$7-0H:(<C2H!;@1(>,(;B!B46/6+79*A@*1+)C;'.*A
@r4292
CTCGACACGCTGCAGAACACNCAGCTGCAGAGTGCCATTGTGAAGGCGATGTAT
+
:$:2BAG)1@BG#.D.65,80+@947("C=%*/7)B@A?(D+&84=(#5C;:8@
@r4293
CGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGACCGGNGTCATCCTGCGCATCCGGA
+
.,=7;,F?H&B>?:03A?0F@"-3@/DH=6-;+@F=8G@#7@)7DD/H2.),>)**>68HED%B+&!9'<!-"D29"H18:B*D:)EHA!*"H4'6"/=6!6.A
@r4294
NGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTCGCAAACCNGTAATACACCGTTNGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTNATTTATGCTGGTTACTGTTGCGCC
+
+%"%!('&'#&!"*+&#(*(&&+(&!($*))+#$%"))"**&#)%)!%$"%++!!%+'&)#'$$!""('#')'()&!$"+(#)"'$(#%'"#'!$!+%)#&!"&'+!"+%'+"#%(!#$%)%#'*'*(+&%$'''%$*)*+&$!%%!&)!!()"%!""!*'#&)&)'(%+()(&
@r4295
CCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTANGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTAGTGTTCCGGGCTGGTGA
+
38?$GF5*(/-&,*&<H&>6H=.-G)2+@$FF>%08,)'*-B?C=1#5@>.14B&4/,G167*H.:(58E-9/"GDG%//G(D,2(9&F<9B&)"#84@,C%:-
@r4296
ANTTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACA
+
)!#&+)+!&&#%!+"$#'++*+(*%'*"%(%%++'+%+'&%!)+(%%'+%'*$&&#)%)!
@r4297
CGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCNGTGC
+
(%*+*$!%+'%"'+)($#!)'$'!('!*&$$&""#'"$'!&&&&'$#&#"+#
@r4298
TGCACCATNGAACAGGTTATCGAAATCAGCCACAGCGCNTCCCGNTATTGCATTCGGGCCAGGCCGCGCTCTGTC
+
#$$)#'$("$+*!")&#()"&'$&+$%)*$+())!'$*)('#%!)%("!'*&'++%$&%&)($%'+"%!'!"&!!
@r4299
AAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAANTGCAATGCGGAATACCTCAGTGGCGTGGAGTCCAGGTATACAGATTAATCCGGCAG
+
5,=C8*+<8#D6"E3"&:?H;/(>@;:>$;1E/!204+$&=8?1EB5<3A(?1@"'C-=-<F.E5:"H2BD7--5>(!.)*>3.'(5@H4/"04::H;;=6@A<H!.'=4C*
@r4300
CAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGNTCTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTNCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGGTATTCCCCTCC
+
)C*9252:847!:9%/4HF!1"!9"%<)=$&>$B-4"H-;-#7&H.%7*45,-5G8C6@";A-F=>-31,)<;/=/*8;@"4F@H(3B''GG!192E0H9"&H.HC8&(5<@?3?B?.%,19&G+)8$&;!CG;G;:>/EH$CE34+&4.#!-BHC8AB48!-)2F(E#3D37@@/;/%B<0'$0,D%'CF9CD2:D7>%CF6:BF9>7G*B/72,04!*HA8<G-$-2D/7'4=";/
@r4301
GATGNAACAATACCAGCACTATCCGTATGACTACGACTATTGATAAAAATCAAT
+
0+3*G"?EC)EA3>8';"(H111:"&78G<933)>=5**FA%@"5<?!F":/4/
@r4302
GGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGT
+
<*5H>;.A9#-C<A--F'D1F41*;-5@/E*''D#A(AF'/:(:C''#1.=*=1&-H1B*2"79D%1F##/&<A;:5&?A3?<G?$
@r4303
NAGCCCCCNGCTTTTCGCNTCAATGGCGGCCCGTTTTGCCCGTTGCTGATGTGCGAATTTCTCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGNCAANTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATG
+
#6!8.,E(#)1:3:H3G%'?@,>F..H>C&/3.'>=<'A%8+5+3*0;..F/)@'09B5!+!!(6*?(50$&C)3;$#1G6",7>-5B:63E;'/!D3$7G2344"/:1)+4"(4'16$.#;$95/*,;'B=E#160@G5AE)6-'/!#:D<"ACB#%F
@r4304
AGTGAGTATGAGTACCCTTTTTTTTCTCATGTTGAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAAN
+
/174#90?>6?-$G#)+HD=9<>5?EG)84A#DH6>-*<'#>5$"H$;@,E7<3G=66B6;#?-;?FGF.D*";D5$>$/>4@;C(2#151=0<0(109CB=?9
@r4305
TTGGATCCACGCCGGCCGGTGAGAATTCGNCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATANTTCTTTAAAAATGGCAACCTGAGCCNTCGGTAAAACCTTCCATGTGATACGAGGN
+
F36><4H*/'0$&F;AH(G)4'<5/!C-B,#5%@F(/%*'.1E'-/@$:/;GH2@+/8B'4(G=7+".29*-A6=A/,9AH0%<<;30,:<B-@-.,%)B>5-,D?17:E$HA'G)2G/*++&H'9,>#?#'
@r4306
AAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGANCCGGCGTCGGTATCGTTCCGGATTGCCGC
+
"'F;";<'62<(-:4,2.:&8633)A.<29',)0F92(57@4")=#?%>&83@?;,F<G"CAC6G@"?,%A9H9HF<7'?A@E(!ED6*,%92>8@2CA":04.%'7?085="D%0.6<CF59955&EA89=9$"5)A:HH.@6+,+$8H$D4E5.;8*$H5+01(5>#37*14-A.:5&01:#3!D%-3:$F'6/-F+G,7,0*1
@r4307
CAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTT
+
.DE@H'3462H-AH3='@44/0&$EC<7CD-.46E0)!2648.%FG$>H6B!A(;;-?=6:&->5;6)A1246G,B>!)1
@r4308
TAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGC
+
2'DC&H@2B?(&>!,+6<7?:?;9"1"G9CF0<5";9%:''8#4,'(>18AD;!55FA6E+-/60H=&2/79+0CAAC4>!/7@0F6&A(4D4$E(8H3-:@C125/0<F"/
@r4309
GCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGANAACATCTGCAATCCCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTT
+
%+%'))%'&$+)+!)+"%%**'&)!)*'$#)"&#%!++"(*(&%$'"&(''"#'#*(%"'!"#*#))'$)+("'*#!(!&+*%%*'+'*##%+*(("*('**'"#)*)'(++$)!$%&'(*%""'#!!*)$'&!#%''#$&#$(#'+!)())+!+%!"($)%+*#$!!$(())%+"#!(+*!!(##&++))%*#')('#!+%)')'&+*$!$$'+#!*!!+!*%*!+'$*!*!'%&'$('%(&$("$++#"
@r4310
NTCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCG
+
,=+.$C*H:#7#FF/5!700D&/2??''G?=BH2::-9'.267<A(2.&<5/:3*2
@r4311
TCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCC
+
(77('98.6A+,>C;0G'$'(*5)C6DB--(D&B314>E=A)<DH%/!82/,'A%))<2A"2?#6*:(<@'6256-"A8G1G5D;E*CE4,'<@823$!B-H$?='&B6E(<H/?H;!:66B>/>8?45B95:8(++3D&6$$89,95'9C)%A9BG>/H?,=5/FC?8?&;C'>-<HA3C7G642)'/A9/+,'<300@$6/81/6<82'6H.7$42@B!C39D@.&!@B@>3%F!05,3,?)6+)!"9&C
@r4312
AAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGNTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGC
+
->-"<E'F=!$FB5<73(??B69*@,;=C36H@H,0,8-7+0'%#7=4B!3!H'-2&6D..E7@""6#D>"1:<#!??9D6-A$F,#?A%:5G7+=H9;&9H(*-
@r4313
NGACCTGGNCAGACAGGACTGCGCGGGCANTCAAGTCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCT
+
"#:0H/1&,"B"E05H(FH>0$-B@*0"/&*$2D;@7@:EA2@78>#='7(>#(?-$E)")?#;,@@#;:?
@r4314
CTGAAGAGTCGGCGAGCCTNGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGG
+
"+;H@-D;09=B9'3A+4%D#2/39>::6(D+3'=<G&!;"8>$!#<F5;&H>?;3.#>9$%6D<@61,")=8=&80@*0!.#8<8HH3&GE'!?</%26+<,!C0)FB9<<DC*:'2@<3??<8(:C568,8'.A7=85A
@r4315
NTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTNATCGTGAAGATGACTGGTGGNGTAACGGCCATAATCTCTAT
+
";4?E3@-)*4/+6;4-*#AGG7FAAG9-*)%@G,=E-&*F!D/+80<,!H@3+:;(AED@9.@G,-7'($<)%&(+AA=5F4"!D3F$):'3+6C9""E@70A6$*%%:?<5'*)#+;"/
@r4316
GCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACT
+
/"<!C/3%.6/A@@<HA.-G?*.=6)%0&;9#EC$/$43+512
@r4317
NCGCNGNNANTCNNGTCNNNAACTTTTGCNAGACGCGACCACTCAACGTCTGAAAGC
+
!%)'"*&!*!%""$"&)#!#*)')+(!*(!*$"!$%"!&+&$)$(&&&!+###&!)*
@r4318
ATTAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAG
+
24)F-8F"8!F%4/.>(:H470"6B?@D+CD3,(G=8%BCF%!64#:,
@r4319
TGCGAAANCTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATA
+
AG'):',-!*D==+1+C=2%7>+22446'!+*1G>@G4G$%.!-74+'")(9G-*7:/0"1
@r4320
TGAAGAATGCGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCAT
+
B%-@A,3!+D'@""?H<<E4G1;)5?5$:>F-B3#;#+">"E(#%%G$43"A=</E511%>8%:E#9425,3<!(7G%3A
@r4321
TTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATC
+
.@";$9C%.-6EB#6'>57D83-#7?=7DBE9>2,<6'8$D%09!>A/)9<F73<
@r4322
TCACCATGTTGGCTCAGACTTGNAATGGAACTGGCTGTTGTTACGGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTT
+
;-=/G6/?8-'CHBH*ED"CC5.)H1"D#A()H47.(6DA+'H@'87&<337$)"!8!/=C)F1)9D1*17&G'"(CG47E4#AAC-<E.#F1C!B!52#,E"&9
@r4323
ACGGTGTGACCGTCACGCTTTCNGAACTGTCAGCCCTGCAGCGCATTG
+
F+/4%3<)':=+)&.6H"4F9==<DB....,G(::6237*E=;3)%*0
@r4324
CTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAA
+
E4.;.E?%3GA;30:424%=CDA3CC9>!&2)2D.)7G8()BC+$/
@r4325
GAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCANCACGGCGATGCCGTTCATGACCTNATAACTGCGGGC
+
;.:>=@,4AC=2>*;#B5$/$F2B--:AH-#?@2)(#3-8H>0$1EB0#7;8AE+!676+@;06EE+7&+>;%AC+3E?2DHC09%9>'
@r4326
AGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGTTAAGTCGCAGATCAGNAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGT
+
B<6#C:H968G"38"0#"<!@,$4$"*'2BB-G-,"95"B(#F!/4<&<*#!)C9-0&!3G&8D(.0#*@>,#@5&($-G#12=DEGA0@!&5'&.%G!'"%*&>1C%=C=9>38/ABB"B<2)-HEF#!&5.(@"0#2A!C#:<%'=&!(F7.DABAB-
@r4327
TTCTTCCTGTCGCGTCATTCATCCTCTCCGNATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTNCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGA
+
E!!((%%0-/5B86/*,(C--">1%BG5&-'(!C%;56)!F*$GDB8A?#/6G$52'-D)"5:(6EEG;=6*0'<=D/<C6:5?E$F!F2H:@,+&<"D</,)#6F$$="0&5'(?+?D?<*4G'+23!020E#
@r4328
GGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTC
+
>(%33,27$0F+#8"/=.=@"E2,44,:,BDA/=)4)A22!!(A$HH963FH7,.=29:!!F:#"5+H0*6=05)
@r4329
AATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCNATGTTTGTGGCGCAGGGCAACCAGATATTCATNAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGC
+
E&$/<6'C++:@#A*).:7>#4<-44#E1>)F$F4'A@=D'DC6&09%.7(72EE<&%5H&>?GB@,*D<GG)CG?&&%'0E<!46!%9=5"53H9@50@H6+=/#<!?9(!70.4</6(F/5,F(
@r4330
NGNGNATNCNNACTAANTNCTTTACCCATTCCTCACGCTCCATAAATG
+
$)*$')'*'$%"&%#%)+))))(%'!#!"+%+&&()"*)%$++!$*+!
@r4331
TCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGA
+
(*F**(;C=&'63)9&>,9'*;D47(8F,!G8F*&/>HB8%0?GB:?DGH:*1;4A"3/576;E?81*2@E$'-0G*0:A0"#7D,GG;@=$)(H0(F6G3@-$=A9CB3;)4&?..B!&&H<,?=D!$2;A-*6C&
@r4332
AAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGANGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTT
+
2"@F497513.#GEDE9/=<@BB)(@/?AEG*<#2%CG.B)+81(9">9>==0>#AC4:G>:@)$5=F9(=<3)202,,*'897%C82C(7&!/A43>5>8>F><1*?"F%0;*?/?C,'7=.)C/D193*D?-0>6B%5/02%
@r4333
NCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTGACCGCCGG
+
)A3G7&HGE"?<22;@*FE;A(B,,6@F8!F(?;$C3)4G.F&5>BB);-$%<,'?8=E,A6"D.,6&,6@DF@H/#C#G?'.9(2#4CA71=FD=717(C8$!>:!&<;9;AG(@;
@r4334
CAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCC
+
H=8"5B43.F,'"=;6)<10*8,$,F77?;,/-4!.('@9F6C4+EF'*$79-G**-+HC/+;1B(*A#(2,!$
@r4335
NNGCACTGGCNNANGGGNNNCGNNGTAATANGNCNTNNANCNGNTNNTNNATNNCGNNNGTNCNNTTAANNNAATANATCNCNAANCCNCGNTNNGAACTNNCNGNATTNNCNGNNAACNGTTNNNNNNNNGCNNT
+
#$$##"$$#$"#$"$!$$#"$#!!"!"#!!!"#$$#!!#""$#!"#!""$#$"#!"!!"#"#$!$#""$#""##!##"$""$"#$!$$"!#""!#!!$$"""#!!##$"!!$!""!$!$!$#$"!$$!!"!##"##
@r4336
GGCTAAATTCCGACTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTC
+
DC":*==*"0AD7F7?D?#%EE(?&%93"2=C;&1)@F6G'6!=>*5;6)C?24#<3-/,-23E4+4@>7H1;6#@A-2A%&)::FG:+B7";;9G<5-)&21,/F2-)7@278,!$&F-%6<&6
@r4337
NCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTAGTA
+
"3G,;?D!8$%B@(=;1C?:-'6AC'6%:6,31?(0('(?5><9%7H;"7=:1!;C74@294$G#9B&*C!#7(%$-&F<'5//2%>8E";0&1;167&.((9$H)2=!)=)B*F#86&<C/=E*=F36AA2
@r4338
TGGGCATAGAATTAACTGTCACCTCAAAAGGTATAGTTAAATCACTNAATCCGGNAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTT
+
'5G;=5BA=8?7D&:+@=0?(+(4=#G(?,!4>)F,"=C#1D<7>!3F1GE31#$>!AE+99,-87:&E0-9G<%#=:,#%=B&&E9D.+&9'0)GD;);2/6-"05?,+6A0/#.8!?F6?&D4$D925*;F+%E7(69@?!3+F,,H".5(FB5>,%471=H=$?H-=4#,FE;:(H)F$
@r4339
ATCNAGTTCGATGATTAACGGAAGTTCATCTGNTTTATGGGCAAGAGCTTTGGCCAGAATTTCTTTGTCGTNATC
+
!**)('+&$"#%+$"#(((!)+!((%#))*))%'*%+)%'("#+"!"$)(+&&&+)(!"')%"*"!"+%$#*)+*
@r4340
GCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCT
+
H'#B,26)"+=0#$-5?,+#9,*7/%B34:A?+9*9(>8A(0)B/D8E',D62=A8%;"
@r4341
CATGCANCAACGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGC
+
$(#&!"&))#+%%(%%"#&'%*&)#*&&!&($'("#$"&%((%*$"'$!(((++*#)&+)
@r4342
NCGNNNCAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAAT
+
!$'!)!)#+"$!'"%+#"(!$&#%&&($()"&*+""'*%*))"&)+(&%#&#'&'$(&#+*&!+&&!'(#+*)*)&+'$($()$!&#!'!!)!&$
@r4343
AATCNGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATG
+
)''!"(+*$)#$&)#)#"%#$&&#!'"*!(##$!*$%*&)%%
@r4344
TAGANGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATNAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGC
+
7?(+);84E4;2*%/<B,>*,->@D=F-H0-;9@&8'C5#:>82D3;*7>:<:?:C6+C<@C$@E43B34A8C95"F3/F5;<*(9
@r4345
CCGGACTGCGTGATGTTATTCTCCTCACTGTGGCCCATATCCACCTCAACCGGATCGAAGGCTT
+
EF,@&5:F")@9B/*'/57D8CFD8&$+9%@8B2C?$E.B0"A0:9=B%$9,H*D.2#2:%!!5
@r4346
GTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACNGGACAAAAATGCGCAGCANCAGAGCGATACCGAAGCGTCACGGCTGAAATATAAGGAAGAGGCGCAGAAGGCTTACGAACGNCTGCA
+
$*+'E!>+<C/$E0?2$G()+B*4$:3?'98<G+D/;G!5G/)>*4<5=755+5!@1)%H?<E7=?50%@F2&A>G07D#8+0F"8!"G&*D<C.:H>;H3<0'$EB(B3#81D0=>@)6G-!:8%=793E*!G-.<BG3+F331<12+A4%61-C9!)5;?$
@r4347
CGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGA
+
@2)C-<26:10&,/$F@-+)%$;"*'>":'9,6791&+!.5:A#!%<$-8?CC4,/=0,CGB
@r4348
NCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCATCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCNCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAANTGCACTTCCGAGTCAGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGG
+
#3':$HD&2-+#5%%=A?)<?%+,A0(,%(46!6=3EFD1B2"HC)+&*$&$$9(5C("G6&?H;*)'-&6,201$1;5F5+**(:$2,&)/:)+C-/!G<GHF/#F!&6+D())A6B@-3.59C,9*'BC;30.:@?3CBH*>D$"D:0&*E+E2.HE9.*,A%-')'/9)9;<39124F$AFA$9A%C(.8"))9,G@,3$##*B"):46D:=">/&G)"%58/!(==.*G#E0-;*>0&)/6"!+-13%DB<0D42
@r4349
TGTTGCCGCCAAATAAATTGCNGTTATTTTAATAAAATTAAGGGTTACTATATGCTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGNATTCCTACGAGCAG
+
(H=3@E6/?&@9(B>>$5B'#8#/4>B(0>>6-1F<#""0$>25!/=.=!B6256GE<-!)<0)-#(/-!;;GH+9(.E)551E=:1F0!;:;GGB8B0=D3&6'$(@>99GH060*:60D>"/:44
@r4350
TTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACACTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGT
+
3*B0"E!)<>(E')'.A&@%.="<'!G9B*87@;%!>#4:%,#,>F#G"CB7<+)/2E>'4<..(8CGD309$:(8$*,A-0:0C8,5D+,GB%A;G90!
@r4351
NAGACTATCGCACNATCAGCCAGAANACCGAATTTTGCTGGGT
+
'D7!H+!$0<&G5!&E%78)4;?;0'G#$:*$"639:7*@.C@
@r4352
TTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGNTTTGGGATTAGCATCGTCACAGCGCGATA
+
85F41/A1D*?)B>"4&'B?@5A.H+1>?=D0/'B&7*>?(<)",#/0-:79,CCH8D-$1;HF/):0%/2"1*/9;709.55'!.)!7G
@r4353
CCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTANCGTTATNAGCTGACGGACAGTGTCGGGGTGATGGCGTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGT
+
6-"&+<F(/0;,?'%<1/EF2$E=<C,0C;1G>"<<1%;A:)GE&':99A+'A<EA4!5(B>E:+H6B0F)2G-H31?>D25%!3,)/6$=C9':,'"217;##(=GE8<#)
@r4354
GTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGC
+
E.@?2)=*BA82-,;)%A@83B/<!+1DE(2C7'!**G#-D>
@r4355
NGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTANGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTGCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCG
+
%/4)=B+F7#(.DH-+0:*%C;*2>E;=E;@H+F?8'HF:0"!6?3A#61>'?.()CA.$%0>("7*)83(%-#-#G1#2AB%?5E."HB1*1B07A+B>DC5A1<(@<.+2?&/9-'$$7A)*6-?E&8#$B1<"<F'>D#4:/-'6/1H4>$+3G@%&:#(F'66FF5F.H(+F*C0+DDE9.*8;>@#/>6?1/EDB837.2=%:"-;7&)7'>
@r4356
NTNCGCGTNTACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTNTGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGANCAACGCCATTCATGCAGGCCG
+
!"#&'"&'"+*&''%!))$!!$""(#+!!'!+#!+)$""+()'+%&+!'+*(*(%#'*'+(!'!*$*!"'"%*')&+'!***%$%(**"#%(&$+"&)!)&")"!&%*))$!$#"##!"$$&$"&")'"*("#&"#*'#!+#''$+#!&(+*"&!$'+$$+"!!!#""!'
@r4357
AGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTT
+
A++A0<=9A;A>A:"!.:855F:0EBB??3&>!H;;?A=.E&F96#&,2##>/5::6%+AC7?"+C=""(,+C$H-":!<H*/,>*D7=5595'0:$':F1(G8D3>E;@*9DA1*H.>DE8:'6CB<5>"6*&29E,B'$
@r4358
TAAACGAAACTGAAACAAGCGANCGAAAATATCCCTTTGGGAT
+
.%@)9@;3**F7-*,A6;5678D')H0+9733G#/*.6.957D
@r4359
CGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCG
+
H:5'99?/A:)#FE/,$<-;<(5>+*9CE@$!0E>"(*=&<G//4%9-,943%B!;E4C)&'A4#%05//'$$*E1>!0$2A)?H?3:D1:>*.A;4A
@r4360
GATCTCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTNATCCAGTGAGGAGAAAT
+
'$+%&)*'*)#%(#*&("%!&++)*#(*'&*&*(#(#+!##$+$'$%$&+(%&)**#')'!)"!)"'$%")&)&'%*$+(+##+"$)+"*%)$+)!))
@r4361
NACGCCCACCATTCCCACCCTTCTGGGGCNGGACGGCATGACATCGCTGCGCGA
+
""-'?@*3"@%'&;*=HG<7&5;<B-F9;A''6=H.!0)8"9GC"30H=(D?2+
@r4362
CGGTGCTGGACNCTGNGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGNNGGGA
+
+77/90BG-<1;8-92GC4%6A-52'*0<?)11C+#8GH%!/6?"/#;;35@6(!59"-++GD63/$.A/516!GH8*,271#2G&>0@
@r4363
TGTTTTTCTATCGTATTGCGANAATTTTTAGCCNAGGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGT
+
+7E:==%4>>B7EB#G*A+"0=(<+-(*8($)3H#,+6%7*A20<8-(E#A.H>+(#:;F7'@35%#<&0F7-2:$C@43"1B(:937%0;4%F.!:#,)<8C-6*<()DG!80.886(*2.0G/F44"&9/.+
@r4364
TATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCTGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGANCAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGC
+
F1D-DDB?'B>'<F/E9A.3GFH+0;<59="%$+(4A>12</>!=0/8#C"6?#4&.78D0"$A)8&@"%>E-AC?.>>;#&;;'C<50A;A7&:@;E.25"8,G+./6)<F5+)(0E45C*.63=:D?"5-(6.1;35$017'=C/')-G2-'&C">(!/&+8,7B-,/7"0,E5$1?#&
@r4365
CTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGA
+
*B/H+6#3(H>88B$<1&5F+2D"2%=#885)''98H*85.A=;(6:3."F4>'6132%AH:)8/65/D:C3$6=:!-
@r4366
TGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCTTAATGTGTGTATTGCCGTTTCTGTCTTTG
+
#A648;!#F*5&05GD/3H(#@65)!="CBH-):(@'.$>9/24-G07E%A,'77/@-!2<)78."91+&B3"H&D3=#(;(<(3(83'>0D$B
@r4367
GNNNNATNANNGTANNNANGNNNNTTGNNANNNNTCGCGNGN
+
#!!#"####!#!"$!#!$"$"$!""!$$!"#!"$"$$!$"$!
@r4368
GCTNGCTGCGGCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCANCGGAAGCACCTCTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACT
+
*!(!&)*+#$++(*)#!"")!##+'%#%()#*#$*!+!$*+!)!(%$"#*''!$*'+%"&"$+$$'"!$!**+%*$#%$%!$!(+"**)#%+!(%+))*(*##%*+"*"(!'"%&%'+")$)#((#%*%$+$)))!'*(('!)!$%+)%$&&("*#""%$)!!!*%(+#)$#)*##+)*+)('"$"&+)
@r4369
GATGGNTGCACAANCACGCCGCCGCGAACGTCGCGCANANAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTATGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCANTAAAG
+
+*&##)*!%"!&!'*!%&)!"$*%"'*$$+&%&)(""("$+"%+)##'*)$!+*!)!+*(!"$"'!*!"$%#$(#!$%'*'!')#")$#"%*()$$%(*!&*+))'$!)")*'+%(#$++&)+*!&%#"""'"$*)+$"!*'!&+)*%%(($&!%$#&)"
@r4370
TGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAA
+
6G:-0C++!(7'H2?(;2A)/E>3D/=@#8+*F#&0E%??!2)9?)FEG,4;4(&>@.FG;/B;+>:9'(2.7.H431""B/:'-?7C",20!9G11#D3E>F0+H."@-(58,6E#E.,&@;D)5F(C
@r4371
TTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCCTCAAAGACAGTAAGATAAAACATTGTAACAAAGGAA
+
#+%$+!$)+#$())++!""))')*&*)#((')(!'&*%*%$($%!"%'$*"'#&'&'(%%+''"*#!'&)("$##'#+(!!#"#&&#$')%&#
@r4372
CCTTAAAGCAAATTATGAAAAAAAGAANAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATCGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATAAAATGCTTATAACGCCGCATTNCTTGCAAAAATTCTCAAAGTTAGCGTTGA
+
5/52D<3F.8,=:H2,>853)3+E<-=GH3B*68C2)715BE>G30BC(.-F+C5'.&'#-69#5)B8:=1DE1?/4&C*6<A@9$7B1F;B;F>=,;7G#48H8C+>"*)8H/26$@2#*2*5)B4..<.3%*?4;/5F:!GG$1=9(@*:096HE9F/ED"(?/G(9B@
@r4373
GGAGACGGGCAATCAGTTCATCTTTCGTNATGGACTCCTCCACAGAGAAACAATGGC
+
F789E*-#?892-28.F"0*1!;063?6@:.1A2E$6.-,!&05D$H*<$E'"E"#"
@r4374
NCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACT
+
'H/!2-F?,G2F&./:G/&@>@<0A6G&)<79"@&CG&=HH=&CE"8+H(&;4
@r4375
CAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATANAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATGGCTTATGAAGGCTCCGG
+
;@<*:H,8"76F;9A3#-$D7879%F%56&./CA$!B+7%,'%"=55?>9#878%:G2(+&#F/&>7(15F%6;5@!+9/%0.5'7"@0-9
@r4376
TTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGA
+
:0=:E#6;)9=32$>.)6%-<9F+5*%$(*)96#!D2B73A'(2C*)@98,,*>
@r4377
ATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGTAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCNTCGCTGCTGGCGCTCGCCCCGTGGTATGGCAAAAAGCACCNGGATAACACGCTCACCATGAA
+
)8*=)H:/0H'.D&,&9)C;G$D*HF4=8(.<)<8FG?#'4,<F?*E%8'.F/EGE$=F*%!'C!6.,89-D":(F/)4&+H50H*HF:/)'#@<:*'40-C?)7>6=0F%&7HB)+D,A(0#-87$6:<>3%-%E(F,;H#?6<$"E%86/2D<;A+4?-;-"00&%#-C!?!!'CB?#+E;H2'-A?02A#"BD4?&7&%<!G/<;>,;57..+!*1E@$:?+B,53,3A58<AF?6@2!:5!0(=+F-?/&
@r4378
GGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACT
+
A8-*%FC1=033?H*E$41E;D.;#5<B(6@E('+(>=80*.:%5%7'H&@EH:1:7=E5GF"+B;/=;
@r4379
CNTGNCCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATC
+
*!%)&#*$+%'*))*())'*)*$#&%'##$#))$!*"%'**)%"#(*'%*#"++$+(+*"
@r4380
CGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGNTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAG
+
H?G;#9-CH%52:,BG2$:?8FG@0$)&0/2@"(1G$>4G'5H*B-:FH/$8"%8H%&92'.!-0<G&)4%-(-.'0.G-4'=G2#04;&/C,,8(A&052)?(3
@r4381
ATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCTGCAGGTACAGCAGGTAG
+
',%>A8@45EG%F<C1B9"9.#>$&=F#:D#1:'AE3F4$*.>$(F.=?*E=&=*
@r4382
ATACCCGGGAGTGATTTCCGTCTTAGGGTNATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTA
+
-G<H7)6++:E5"';-62@755-@7?C/6.;5'.E<D$0<F@8'D9?H)8457#B;H$89>76(A'3(,6/9)3A-!0@C%
@r4383
GCAATCACAAGCCGNATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGGCAAACAAAAGGCTATCAACTATC
+
-F-<3/8G563$&B@?D<2D?;BD7'7.27A9AF0)$*%6H,+)*3!6FC'G#B*//3*E9$@'FGDA=%&);,#&((-9CE!"*B
@r4384
TATTAAAGGTCTTAGGGGCAANAGATATTGAAGGGGAGCTTTTTGNCTCATTGCATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTT
+
@>@!#23+3,=H9"5(*;+%%;,8:%3,$=589;'<7/+)%3(?#=?E'1E'?D4F:3<'DB;-,4')!2#GG',2/,/#ED3;F4$1(D=";1G1F2%A;E3$?B77!*9.!<
@r4385
CTCCCCNCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTGTNTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTNCCATCTTTT
+
-'-B@%FFG&&@%-?/(-1<&G2'A,;//5$?E.:21B6&?A"97A:96HH(3<6$?&F,'7<*324('"A37,AH"C*-E,6>.B12/+6D,##8<-/E4=:-@F$G>!B:D?"?)::2D<-)'G+/6=2#4F$1G;6%0.)*E6!%A"F>5D=C$B0308E2='%*"=3!/5).1G,$/5A94@G%$:>##7>?0G/3@FBE)=B&DGG7>>#(;5()2G"1+A0//11@6/7*-"856@!+9(757D>'/=CD4-#252&>>.%'CG%#H6&)%>8;=23/59G=<-<.F,2>!(/(D3107$*"=
@r4386
NCNANTNNNGNANNANGNGGNCCGCTNGNNNCNTTNNNCNNNNCGCNNCCNNNANNANNNCNGNCNGTCTNCCGNCNNCGCANANCGNGNGNNAGNANTNCAANGTNTGGCNNCTNNCNCGCNAGGNCAACNTNGAGNNNTGTGNNCNANNANNGTTCNGGGNNNTNNNAG
+
##$!!"!"!#!$!"$"$$!$"#$$"""$"$"#!!!"!"#"$$"##"""$$!$!$#!$##!##$!##"###"$#"##$!$#!$##!$"!!"$"!#""$!##$##!"!!"!#!"$#!$!!$!#$$!!$!"###"!!$!"$"$$"#"!"#!"!#$$$##!"!$$$#!#"!!!$!
@r4387
ATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCC
+
5F9.2,'<@)H=56>/D9HEA)%:$.4H,152&;B:<88H72;H8G;:C(.D?3=&='1!5"EC0"
@r4388
GCATTCTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCT
+
AC#(69@(;B1)&7*>!&%G;G??/8?@(/%?='-0?5#<(0A?=,D9':8
@r4389
CTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGG
+
<6$%E!$./.4#$$')%,?FF2+"05D*#5:$"G56.D!G5"(C58&16>!D)EHB78<?@788"7C6G&7><4'D.93?
@r4390
NANGACAAGAGTCTGGTTCAGAAGNTAAATCGCTCTAAAGCTTCAGTNGAAGATATTAAGAACAGCCTCGCAGAT
+
!&%+)!")&(!!!))%"'#$(%))#*$%"&%$'%)%$((*($+$)')%)*%#('+'!+"%%+&&%*#$)#'%!+"
@r4391
CAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGC
+
=F7$@A8/!))*:0CB2:6D9)<%*BF.F6F+D($/*8*>=G%#6A!%E>'=*##CA
@r4392
NNATCGNANNCGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTC
+
$!)%%#!*!!"+&)"()($*$%'$"($%+*($#''*&)+$&%%'"'"#%*(&&!+'
@r4393
CATATACATCAATTNAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAG
+
<.-9>B$2**,%7!3;9:,@90F'8*3F1>;##&4'8(9?0DC5.BA/.5)+9@!<%H2,HB6(&;H2":5B,3)@B@0&<.A$HH961<9B1*=2*=HB-$=-=5?>'+B#+3EB#"C0FDFD2C'C=(0>"2&/45&/C,%36987<"3/8E32G-;1-*4,5E#9*H)H;(69);<4?>3)/89%*0=#+(:#>8(B(--9A?$*8=B.8=3,8A4%4H0!+'9'$@H%:?$H50:=C>+'546+=28-,8!?!<"="D<=6HA8%:1G-<G6*9E#<,5==$6-4>530>-38E*A2@*)<,C@9.-(".4AG%H((FDB1;CF5GC9>B,.,#.&H+E0.B)0@A,89%H-F*!!D>E8C11%++0G#E(>;E%/0(25H"<CA)&+#)5
@r4394
CGNTGNANGAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGG
+
**"#%"#$%"+"+$$))"'()&%!(*$%!'*$"&#''%!$##&*('!&#('+"(#*"*%+!&'*&!&"++%&)&%('+*&*!
@r4395
TGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCA
+
766,&EAD:'=:+4&FG71ED8;%(#:HH"+<D8;D'42F9%A='=H#3
@r4396
NGTNNNTNTCNNNNTNGNGTAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTG
+
)((&(#(#*'(%$"#!%#*+*'"#""+*&$#'"##"&&*#)$!()(($()"+##%$%*#$)*%+'&'+"!&(+&()&$*'($#&$&)*&*"#'$'%#(&*&+)###&%")((&*()&+)%$$&$'%'$&'+
@r4397
AAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCC
+
*,3;0HE#B02*'04*C'?2?<0,3/"<1=$-15E>)3G;*A#F5B-16CEDGCC-/0GC,)7<&8#4+%E(8A+
@r4398
TNCATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATNG
+
%!"%+'"*+$"((+)%$$('#'((&$!)(&!((&##&*+#)(!+)'&*%+&#*)%
@r4399
CTATGCGCCGACNAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGNCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTNTGTCATTGCATGGGATCATTGGGTACTGTGGGTT
+
'?$!'.G%2@G+"=5/2*95H;9:(E@7C$A$#$G!:94A6$;-2,@G#-0?0?..)C!2=4*==(,5<1A1H"@+F8DA>$.F9!==0;81A..;0=&6.GH;2/;'!@#DH/&*$*:G9,8
@r4400
ACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACNCGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTCCGTCTGCATGTGCTATCTGCGCCCANATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGNATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCC
+
)"+)(*!%!#++%(!+*''%$&'($'#'"%#'("("%)+))*!"!)($%#!$#&"$'+"''#"&&+'('%!"#%&&'#++&(!"*)'&%%'('&%%%#)&'$)#+")&*'&#**'&%"#%*"$()++)$(!*&**"!(')!'*%**")&)'*)*$"'+!##"+%+%&"*$)++*+)&#'*$*+'#%+"!#()%!$"%+!&'&'$%##'"+*$&'&#"()'"$&%'(($&+')&%&$$())*+)$%%)'(!&$#+%&*%)#*##'*%%%("
@r4401
CCAGCTATGATCCCTATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGAT
+
)(8$/C54A9-G=CD(*G-1"3(#&8821;G.%C;1BD:%35+/7&'"%:E==9'F!.>&D>@3D7,H0(?;.?$9*3!"%$/HGE,:)#@/5!4007#(,H&,7)>.(7<BF3G7?)&"AH!F0?BCDBH@B05;?<!H$&(H,
@r4402
ATGAGTTGCCCATCGATATAGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTT
+
6*"7:).EB8*H%CH*/+4&>2&*7D.4B3:8-?&3>E)A+$%'H:/%5<D#0:E-'2-C''=H5
@r4403
NNATNTTTCTGTACTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGATACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCNCGCAGTGCCTGGGGGAACTGCGACTGGATAGNCT
+
%+%!!%((+*&&%+'$'&#*(("$&'$'**'*&&#+#")&$%!$'$!''+*$+)%#*&$(%!#+($'%(#'!%)%&!*&)$'()($%%"+%&&"&)%%+)!!+&$")"!+)*&)"!&!'(!++#"
@r4404
TCGGCGAAACGTACAGCGCCATGTTCACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGANGCAGAAACAGC
+
7B=:::(0*D;4.;C46/,/<49;5+1BB70,5$,;D$(E.4,9&#EA3#?6"#%#395/"%#/'%7&G=,8E5=1##C@?*9ED1CH!@"!4*'9;>,9H3"E$"<
@r4405
GGCACCNTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCNGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCA
+
*)*!#+)+"'!%$+*"*"+**'%$*$&++"+#+*"++%)&(('!)*+&*$$!+!%$)*%$(&$$)**&(%$"(#$&+"'&!**!!(!&"&$$*&(!&)!'%(!()##'"!)*#")"&+"%"*$%%()'#")(+$'$##$%+%("!!*%!!&(+($#&+#'!)#'+!(')))$&"+))(+!#&
@r4406
CTTCCTCGGTACATANTCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGG
+
+&(("$+$"#*$#(''#+++)(&+%&#))!)("#'*!()"#+#%+&((''&")*
@r4407
TCCGGATNNGTTTNTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTANCGGACCGAGTTCAGAAATAAATAACGAGTCGCCGGAAGCCACGTCATAGACG
+
*'%'$!!!%)$*$"$+'&(''!%)*$'*')%)#%++$!!+%$%&%#($(%+&#$!#"$'"#'+!)$'$(''%$+#%++!%&&$!(%++(%&&(#%!%%#$(%+#!%"'*!!!*%(#%)%%!+!"$**##)%)$()!$&+'"&"&#&''""'"
@r4408
GATGTTNCGNTGANANCCNGNTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATCCCTAATTNAATAGAGCAAATCCCCTTANTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTT
+
)%#&$"%")!%"'(#!)*$#++(!%''#)&'##&)*%'()$#$+%))'#+'$+&"+$&(($+*+(!()*()&('$##)$#$!!(!$!))*)#$!)'%!*(%*+"$('&&!#(+#+(("!$+#%(#%$''%()$%')#$)("#$$%*)#(%!)"!(!)'*(("$(%"'"()+**!"!)')#+(+&'!%$*&")!"$%#(%!"!&)((+!("#(*%$+!+(#(+*$&
@r4409
GCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGG
+
=/F03.G8$6G*/!/46)E$%F4&G;F7(E.H3(0;<;6B"/7E98?*559.:,.##*HEA-2E>5:1,H)G&E@E*@=;E6B=FCBAD80:3&-E4-,/F5?*EC/'3)#0<.%D37A$0:.=93C8%='1:!:H2;?1!9)*!%@AG?&-4*
@r4410
CTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACNGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGTGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAA
+
&=7G<;.A<(-/8@$5'BGBG6F4C!387>!14A/@+.D<,7,47$//<61%*+6C$@-+:90(FHC;1:=(77C*46(%;'.>AB:9/,(3G94?,77&3-09"247?@47>+9?;)@<(FE)G;@18;?'@G*<C%.?A%E-#)6=;&&6&A&5D.9E0G=$>,C'62<#/>8<%105(E-"*!=@
@r4411
NGNTTTTATAANGATNNCCNGGCGAACTGGAGGCAGGAAGACAAACACANAGCTCTTCATCATTTCAAGCTATTAAATATTGCT
+
%&#)*")$&!#!$(%"!)&"%(++%(%$)!$+)+)!+!*("'+(*%*%(('(+)#%(#%$#!!'"&'"#&!("&"#$%)$)*#(
@r4412
CGCTGACGCTCGACCGTGAAATCACGATGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCANCGTGGAG
+
',D996$DF:;=G0=(&(=%"85,>8@+7/';1/9>9G7#5.#'C?,-G%!,%"+DB'$9/>@;-):"13/33DAH@9C!9FD>$H5:FD+B
@r4413
ATTCATGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGC
+
)#%&(!+$)"'''#!%#!&*)%"#&()%+"!%"%$"*+$)#$#'"#"&*#+*$"(+&+$%%''$*))#!+)(!)+$()*!#+%)!))&#*$$&$$$$+#$%(&"+%+")'*((*!
@r4414
GTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGA
+
9'@,95?./)&A'H6..3B;'%B,,2?0B;;:988-0?0GD+>>"#5$34$-<+141+E@7@"$9($8FA/9#<>
@r4415
NAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATNAGGAATNTT
+
'(?D?,GGGA1!6771DF3#*@2=/9,)*626,#&G5H7/?(G'5GD4,!"8$#.,#6.-1BD6E-E?9/(
@r4416
CCTGCGATCCGCGACANCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCT
+
.F$1:B!:F1&%C/G*25&@8G<;?84,C#G@22</.$$E.>0@(/+E#:D(6"4"3*#*
@r4417
GATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTATTATATTGATGTTTATA
+
6EG)0%8+:7G7((2&H2F0!%)G>)2:*#!%'4'70D>8#%:..=19782+,!*,==9#/E>.';AG&C>AB-#@CA9E(H89*<B=
@r4418
GGTGGNATNNNCACCNCNAACAGNTNGNNNNGANTNACNTCNNNCCNAAAAANNNNGACGCTGTGGCATTGCAGCAGA
+
%'%'"$')"#&#&)&%'$&$')("&#)(*)!))&*($""%'&!%*%#'(*)!$""#+*"'&$"&&)&")"%'"#"(!)
@r4419
TCCCTCCGAACAGGACGATATTGTANATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACTTNATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACA
+
.FF))6;-=*(#.04:1C"8C,'7E20:?F!79%2G;7F$D-E4A8,6.@F)-C/56<%(%H6)H"B2?2+)":1*)=#DCB5;<'%>C6AB!#).;!,AG9-BH,"9'=.76<'&,:-5A;3:!5='!%.'20,-;;C"6.C4&.A@HC7='/*D8)H)1,0;/=6*(?&9C$3@?3F04555A!E69-$:(#E,62%AG!&;)@3=(%E&?H-."$+=D2>+"*45=.;:<87&,B':&&%1!;7=$%;16((386@4."*<&&,C1?:F40/6FF53:&D*.F@2+EG,*C3G!)4F*<<!:,)?(E
@r4420
ACCTCCAACCCCGTAATAGCGATGCGTAATNATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACAGCCGCAGAAACTCTTCCAGGT
+
+=D!,E&DD)342<'.''D)3+,9;7/<8HB/()21A44B%/3!+<&DB27/C"(+&%FA/DF)=!4H</=4/F%;;;B$+"@0=74+5
@r4421
GTCATCAGCATTACGTCATCCTCCGTCATGTNCGCCACATCCGGGGAAGCGNGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACT
+
7.>?4;C@H;<"2#*$5FE62'6):(D"'"5C:3H+C?0>48'&2;"&??)9%G,.FG7H)"1"H!F5><;1BF&#)%:'<A223225?#EG%7H>?G?9,#B@F*$0$84B"G$)D1!!;'C'-@:C"81#GH0B"7++/&GHE4DC$@4-$B<*D%3H"%3/BD1
@r4422
GCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGNGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTG
+
(=($24!H%=H69$;5,3$A2@/.313<%$"&H8!,%;8*#1<0:H>E.+&+2G.G%-(:1!1BH!C,:%0;GC3$G7(9=
@r4423
ATNNGCNNAAGCTGGTGGNNCNTGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCNGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGTGAATAACATCAC
+
%'#"#'"#"*"%)*%#)&!!$($+''$($)'!!&#*&))%+$)%**+*""+&!"+$")!"'#(&(*!&('*%$%''('*)+#**!)$'*!))*#&"*!(%'!!))$$%#*!(#&$$*'")*!&*("+($!(#&"''#!)%)(&&'"("(")+(*%$")%#'$)')(''#!$)'(&'!%)"%*(+*#)"'"&$)!%&#$#
@r4424
NGATGAACCGAACCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACT
+
$6$F?H747!D.AEDD8%C+22&F;B.,&H?*@!59:#2C@@@%A@:+-H?16!(+H.&'H+
@r4425
AGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCG
+
D)/%5">$=-&3<+E(3FB8BBH@+9=0(.(G+7#0F)!)7#77=C'D)1E:C,2?-;0E
@r4426
NNNATCGNTGATNNANCCGNNGGCACANGATCANAGACTNAATGGNT
+
)#!')*)$##&#$'$#!((%$*$'!(*(%!)'*&&!"#&!%!#''"!
@r4427
ACGANGAAGANAGNACTTATTCATTAATAGATAAAANATTCAGTCAACTCCCTGAANTGTTATTTTCCTTAGGT
+
$$#&!)&"*#$&(!*'*+&+!$**$)$"%")#"""$+%$+#"*(+"!))&#%$)"(''&)($+$%#&!#*'#))
@r4428
TCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGN
+
81#'%;."9;';6($D)D:!A;B<?F&*!?7@)&+/),:FG4*;/GC534F@<A?";?B61%2:;%!A)BD*7DH.E.%2(36:
@r4429
ATACCGCCTCGTTCNCCGCGCCATCATAAANCACCGCACCGTTCATCAGTACTTTCANATAACACATCGANTACGTTGTCCTGCCGNTGACAGTACGCTTACTTCCGCGANACGTCAGCGGAAGCACCGCTATCTGGCGATCAAAAGGATNGTCATCGGTCACGGT
+
(''+%$++&%+!(($(*"%$!'''*+&*!#*(*%")')*''()&'!#*"*+**"%$#!"+%#%$+#&&+$#&$'"('#+&#"%"(!#"$'"!*%+"+&('!)#!##$''"!*$""'#+")"%&)*&!#$(#&+&)*'$#$'#(&%'+&))!"#&)!*))&+&#('*
@r4430
CAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGANTGCCGTCCACCATCGG
+
?,53DB.!/"H=<$%:F2ED>B:/4D0C53F5+!.#3?B6"@9.$=-GF*A'2<?<(5,-A&%$)4*
@r4431
TCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACC
+
H09<745>+#>)/7GCB-G<8!$/8);'>+A892)DF308%%CC/46*/*":#(4E:-EGCB=(0">1$=3BFG>1%&H1$1:#(!H,@78*==8)5F?A>7$(*5&B?C>%'7
@r4432
ANCTTCCTGTAATGGNTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCAT
+
?</3@=6A.7C*FD2C<,*64.2(0-G&*$C&D21@G+,=">6#*73$(0<#:%+4!"*,<>C3-'(;-,?#2(;;+,:47"1&/E6E.05D.)#5E.)9#$.#;:+G5BB4/84$-
@r4433
CTCTTCGCCCGTGTNTTCAGCGCCGGTGAGATAAACGGCAA
+
)%<,$,:F(,@)'2@E*D3((,5$GA2;2<%,@@179)3@,
@r4434
TCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAAACCAG
+
+79(6+HH'F">?-AA$61/=4=1;2$'.94*(&B9>,F),:-&%+E-E7(F)%
@r4435
AGTGATGAAAACTTTTCAAATATGGAACTCATCACCCCANTTCTAAATATGAAGAGTTAAG
+
)+(&%&%*%%"$%!()"#$+%(#)(+)#*)#%+"#$+"'&*"&%+!%')%%("(+&'("*#
@r4436
CTNACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCNGGGACGCTCAGTAATGTGACGATAGCTTAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGNCGGGGAC
+
3>;61=434F953-)4&'515C;9F%"=#=>2!3D7)!:?$1/:%$+>-C#156!*@%-+F;-B15HH%&@A19H!$30(20'F&<7$@=F6*%2($&;AC#,#4$FDD)<'580931)535%@F.
@r4437
GCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTGGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGACGCCAGCAAGCGCA
+
H#.#@+3!B7<,1CD2+$H,;=8H?"8$<$!"/9").609!*<49&C4"4D9F0C+1=&)+)1=0)HH$G*G-D%6CH;@7@2/!&,13DE@88=9GF1/>&B:+*E5+=$96&'0D.#B?&8#6-<"2;1"*,G=+$#G8(*H'94E!/:8:@..H<70365&B6"8;>"8#DC/+B1;87/G9GH"?">D0ADH69F7<>,A&="5FF(><<?:$'E;@+*;7$06*%F,7,23=)&EG."!+(&-1==(E,2C2E52/$=&'"=G)8F?+'&&@H-#@A
@r4438
CCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTT
+
>AGA2'#B3!.-/%;<**40C:;0+=.E@>9=9H&")?$$.3.G</+2
@r4439
TTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATC
+
"%>H(/=7$#>".-!4''.93'7+F4;!%7%!E+2525#;/=>1#)0=,!2?C0/>G+02F-EF48.%$H0(1H%;4#(:GD?57-!1?-'.6/8:A/41B:!86
@r4440
TGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATNCGTCGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGN
+
5B.#7+8+BB<*A*"@2')FB+:?<1-&7(6/C*C;+G("&)'F##7=<5<'2'6+A$!9&-?B1F8'A(F'C2?@2:./%0B0:+&3?&!,A.:9-FC);<;-4C6H
@r4441
CCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAAC
+
?-931FA4E!!.<2&G8"C-246&<#&79D'2G5?<2EHHG35--B+)'66E$G>A/F@9+5+
@r4442
CCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAG
+
&A(&A+%:G->=.00A8/)%)9H=>@0"CD:23>7(%<B-D>(?#&2H
@r4443
NNTCATCCTGCAGGTTGACGGTTTTCCACCATCGCANGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGGATGATTTTCT
+
##()$+&"#+!*(%($$#(+*'**$")'!)#%+*(*('*("*')&+%+++$$#&%)**&&&()'#$$+("%+()$$&+&$'!&$'"!)$$!+"
@r4444
CGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGA
+
/H'!$;')*9.?F%-C<(:=DD7-:,&%!64G"-$:/8*;#-#>$$594D6%CA4
@r4445
TGNGGGCTGTNAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCNTTTAT
+
)+%"#+!%"")')&"!("$&+'+')&$%"'+$+"%"""!*$&$+(+%+&"!*)%'$$+$##+)'')+%&!$#+!)*%$#++#$&"!!"$()&#&#+%("&&#*%$#(&$(#""+(+%$##)#$)$$%!%%
@r4446
CTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTG
+
>@4D8G1)A.>*/''(F5H$),4GF"=;>7?!+@C1=0;EB++6D"@:;<#3(3H#E86)")!<:6->:!27(.
@r4447
TCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATGGCATAATCTTTCAGGGTTATGCGTTTTTCCATACAACCTCCNTAGT
+
&.CB80.;&)&.10;9C:7#=@F,H4;1!10:!%!>G4(C,8$F=0+;:.8$4F691%64A/>%5CE/H@'C>&+H=+A+'&H#2F76%)B5B:(7<!)"FA??;.>4D=>HBFG8/4<$9A$%7
@r4448
AATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCNATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATG
+
AC93FC$?")C.?@&%G4&>1,&7"!ADH-@?'*4%D>,-C=G=,+7)@$<,B46-D&&G09E;?@80(/E471?=AE<-'"!+>**5F-*F#;940(E:!'#CG<5C+4'!>BD('4'!H)D7FH)>5H8H6#97-;"GC,?=,:0"/5E8#834'9-9+G?H.:F*8;%E!A>-*B:D+F;!-*51C-B>F<2EGG!@0$1=ECA7!3:0$#G5G)1<%&.H-'+%@?"7BED(&5D$=>+5C9G<5&2=G<B'7"H<*47$,)EF'<',-3)(#9=;>>HDA,>C$
@r4449
CAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCC
+
9C3&4,#%D6;;$<".@:G;*G='+H@;H+@)6EFH9"9&DA4B;A$/(D
@r4450
CGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCC
+
370BGB,!("(0.,C*;@H""C2&8>5;%A>>5?-8F0/=8:=2H6?50==
@r4451
ACANGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTNGT
+
F$<"."/%%:EF&>+D)E1HC<0/+@-18"F2>.DF:7$9#41F0H",H9&)(5!(!2@"0#"75&G#EG994'2A/
@r4452
NCTGACCATAACCAGCCCCCGGCAGTGAAGCCCAGATATTG
+
$9".5%2:F1@8B1C<(&,:A1:&)D:1%'F5,$:00?9*.
@r4453
CGTCGGTGACGGACTGAACCTCCACGCTGACCGNATTGCCACTTCCGTCAACCAGGCTTANCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCNCCAGCACACGACCACCGGTGCTGATACCGGCATGGTCATCATCGCNGATTTCAATAACATCGCC
+
A+)762=+>,$6*B9-?:*C07+$)3;F+2E%00%*4F,5%3.F@;2:=+,'@":B#AG$C5F'9:-E.-8&4+741;5/D'3326>.1H?:($&&%<ECG99%;4-3-'$$CC$H/<5'%*(C"#"*H!60@><#H3&%<#D2.7%;):E43;5,(<,6:+=7?$;HA'26#)C+E3#>8!#,B#,4H)3&*?5B
@r4454
CAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCC
+
B66F*FE?>.>A=-?3*!5'8D-#G>?."382??60'HG,1E4/*+H$0&&<;@=E@<G5,B=:68<(B((",8B;>:@@EEGH4@%G1!$6#A".89/G0
@r4455
AAATTTCTGCTCATTTGCCGCCAGCAGTTGGGNGGTTGTGTACATCG
+
3H1),><)&--26?;'."!"E.&%CFE,.,<7A64)!B:D--&?G2(
@r4456
AGCCCGNCNANNCAANGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCNGAGTGACTGTCNCCGCANGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCANCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTATCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGNATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTAC
+
(!$**"%'$!"$&(($)++&%*$*!&)+*$%%%)*$%&&')#'+$*&#(''"$'"!+"'"*$'#)(&$"'!('!#&*!')&&$&()")!'*&()&')##'&"&""*""&%!&%%'$()$)&#$")(&""#(')+#"!)*+&#)+'#%+++('$$+)""("&+"!%'"''"#$""*"'#"'%*"#"!"(*$$+'%%*%++&+%)++!))+$+!!%&&)*+!&#"$$(!"'(#')'+*#'&%)!#("'$#"+())"*((+$&($"!%""##!(%$)+'")!$))'##**&$*'!)!+&#%*)'*""'&'*'%(*!#!($+"$(+"$**"$#$"#!'&!#"+%*%%"+&!%(%%")'!(!*#!&'%"&&!$+((++)!+"('
@r4457
TTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTAGGTATAACAATAATGTT
+
,);E@=@9%*;HFB"7:710?$?8..C2.,>*%7B%&F1$3D$.'3B61!+-&#/DD:@H9:.>(;>F<$2=)25%C&D&D"HGB&C+()FB/'#,'23FB7A#&)$4%(4B#F+%%"=668171
@r4458
CCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAA
+
H*,C3"')&G,A02H0F""A='F#<G+('0D+?5,G0=28;
@r4459
CAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTNCGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGC
+
A93#')A+!6*$C<D+='%1DB-$(%'.-.A3EC6,F'<3:$8>D6!6:$.-6!"G7<>,47-H>(17F5<'"!65+"<5'H36,C?:+?;+5CG"F-G<B8+5(9G?%4F+D@+&)-5/3/9'72$2'=0#A@0(24GF,+G2"C.,D?1:02G+=%&%F
@r4460
AAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATAAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATT
+
;:."B16*&@90;>+&E,EH,@D<?""D,"/!B@-37;!5.24AH,6%/(35$2E-D,4-896!G*+7'-1"*E4748+<.=E9/!D<A+$3&)=6;%>'G*2/6=C5>(D+7+D5;"/%;'BA?$(9=H(D=D4F>G89*-
@r4461
NGTGTCTTGTCTCNATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGCATAGATATAGAGTCGNCATACAAATATTGCATGAANGTTTATAAGTCNAATGAAGACAAATNCCCATTCTGNAATGTGCGAGAAATGACTGATACCGTGCANAATTTTTATCACGAGTACNGTGGAAACGATACTTGCCCTCTCTGTNCAAAACATATAGATGATTAAACCC
+
#%*&''($)%)*'++'#''&#"*#(#%&)%#$!+)*+"$!'$&&**%$*!((#"'+$*#('&&!++('%'!'%#*+!%%!"&"())%"!%%!!!(&*#%%$"(&$(+&#"$&$&#%+()&#!)(%%"%+!+*$)$$*)+#+%$!&"++"!#(*'$"!$+"#$%'"%&&#&&%%+&"*+#(&!""&#")('%(""%%(++&'*'&"+$&)%"#"*&%$&'$'"%
@r4462
TNNNGNNCNGNNNNNNANNNNCNGNGCNNTNNNTNTAATGGANNTCNNNNAAANANANNNNTNTGANTGANGGANTTNANGNNACANCNNNNCNNNGTANNNAGTTGCAGNTNNNNGNNNTGNN
+
$!#"$#"#$"#!$$#"#!!####$!"#"!"$!!!"!"#!!#!#$$$$$#!$$"!!!$#"!!!#$"#!$"#""#"##!#"!#!"#$$!"""$####!$"!"$#!"##"""$$$$!#!"!"!!$#"
@r4463
GGCANCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGA
+
!&&*$+((!(%+*"+)*)'%#""$+(*)+'+)&"&&$#*&
@r4464
GATGGCGGAAGATATGCAGAGTCTNGTCGGCGGAACGGTGGTCCGGCGTAAGCTTTACGCCCTTTTTCTGGATGCGGTGAACTTCGTC
+
;C2)0E.!D4G@7GGF(>/<:>5$$%5F&&B+**&(@!E4;&H,+-1(D<C-?<A-D4#$=D'=FD?@20A4C61.&"@.:73D'64;
@r4465
GCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCG
+
:'#'#B0.:C/G6=9)E=9BD>>*BC383?'*E@3)?$(B#66%:>7&A=/9;;0B1F$='>?)?5?ED3H7)CG=BD/"-@@<5E=><*3"-0A428&-7+7=1H)02<@'3H,8*@<+E$'G+:C(5G
@r4466
CATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAANAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGTTGAACTGTTCGTTCAGG
+
/8,!5394;<H03'-E-3=8@%0;$F(EH&?GBF0D'+.4=-+=DA>9,@5%/(>>:18:,,42!'*23(#2"2$"9;6H.:(5"!@CCFGG,A6?C,C65G>C!9HC-DF@*2/5%!/8GC+36'EAD<=8#/E$8&@HA+8<<".;14%#-=2#>*-0B6)D6$?;E2
@r4467
GTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATACCGTC
+
>5/0D("4B*5'B1A+!15:"A-4F:#=4&>)55+*H7"3.6"B!#>(>A(C7,+0E!(/(/#!=08&B&6!
@r4468
TCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGNCTCCCNGACGTCATCCGGA
+
+)%(%(&*!*+$%%""++*(#$%&*$""&%')*(&#&$*$'**$*%#!(*'"&
@r4469
CCTGCCAGGTGACCGGCTCACCTTTTTCGNTCTGCTCATTACAGAAAAAATA
+
!G0:65)$;D=@+0>GA9<#H1-/"!'E0H'H?:3!>34C2C@'&HC6&$!9
@r4470
AGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTTTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTA
+
1<D?G0%,.%@%:8D+5#&.))14=C8CH.8%76;$,%+9GH145A*)?#7"">(,AC4D.84'-2A-C&%GA"@H=64<&1D;B#/;;:;<;*3E>8*8C<(236?:"H?D,65D+?"6".%*A8.G#"$'7*-7$6.E,$H/)!/E*):381#$'."8
@r4471
NGTGTTCTGCGGAAAAACATTGATACAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGNTGCATTCNGCGGTAAGCANGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGNACACAAGGTATCGGGGAAATACCGTGTTGTGGCAAAGCTTGAAGGAAA
+
""(++((!$&*%"+&)$)&()&$+!!$""%!"(%!+%!)%$$(+'++"#*$+()!)))'*)#$*'$$%&%%)&'&+'"&)%))+')"%*'%*)$*!"!&'$#%!(&%%!")'!!"*!%$!%!'"#!"&*&*'+#)(*(%))**(##"+%*)()#'"$)%(#"&&**)$(&(%+$$"'%)%+%)#%"')#)%!$"#%()!"(""$&#)(!&#"(%&(++!!"&"%!)%)!))!!&!%)**%"#"")+'+'#+!"!%"#!!+)$#%+("%&)*+#)!*!"#%+$**)%'"&+)##+)*(&+*#*&#*%"&"%"(+)
@r4472
TCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGG
+
6/<6.190H:5F>=.1HF48-A-+79*<62")%#F2121A4A/F'=!E<(.
@r4473
CTCACTCCAGCCGGACTTCAGGCCTNCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCC
+
$1E#&@.%.19&"9EG2:,-*6A=($$2G@>2A#%#'8%A0)@H'6/!!,$??EE>E;1+<
@r4474
ACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACAT
+
<F&6>)-)-,&G*6,+>5.2F5,>3H8&B)*$24?%D-$9A1B8A=A1!C.7,2A$#B'(&G*@E3,-,+*G!#)>=B@0*AF/'2=16)=B4%<,A,';."089*2>
@r4475
CGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGA
+
BC$8($GG:;951D+#BD(22,.=&$3G2#C):$#0$</E*($9?1G,."=/"9EF=/++';C%?H,,H?A$,H%#(EH8795@2D,;F?D'79=>9&*D2H!?4"BG>#3;B&/'*G":69%$#+?-E<*>:)15
@r4476
GCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACGTCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCG
+
$.5/3)70*<,A9'5=13?)?C@C-9G764F@B*@=BD.$.;F3F()H;%/@:@5>&>B20*4A1!)(/01?E-5#$#-+DB4'=;8.?4:&6647)H+!),&6.+5'%<F.A7.?A'0H@;)7+D"=
@r4477
GCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGA
+
2(D+/.B2$!49>D!B=$95=6CF2@';HE4HD?8HDE%3$+C"49?9$CE?C=8CB81<=!!4*A!H<#9&@CG'267H3*2
@r4478
CACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTC
+
)+F46*3#(803)B&:7<18;/".<07)=??+/5CD%0B0%?;D?C4;=ECH?#
@r4479
CTTGCCGACATGNGACTTGATCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATACAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTT
+
E3D7.6(B;28DA'<-3@$5E=!H2G-GE()B@;0:.%+C8=G!-;F&<2/8DD)74)EB-/2012*(,,*-2!5%9+%GC-G<-$39**>,5E7@8++;>8'60&>/!!/@#C3(51D?>?@2)-C/ED5HH5$)!,B+1;'1A2C#>;98A,CF0#3)F5-,H!)2&,1&F24<844182'GH5-9F3::38<53E6B'",AA9-."B=8H(;
@r4480
ACNTATATGTGTCGGTTGTATTTCCCTCCAGAATGACAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAAT
+
$)#%'!')+*)+%$+&'%$&%*$!#"'&%*#'+$$#""$"%&'#"*$&+$%($#+!"%(+"#%*"!"&"!&&(%(''("&*%*!%#%#)'*+
@r4481
CCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCA
+
%5C12G356*5,9FB.BF,%2D5-G?B??EB.(D+#'-$8FA#H,<-%.C:$;31!8?3&)6;%'
@r4482
CGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGA
+
+6(>4=C$G;0(%%236,9A8@$B7.9F"B9,73=:#4@0??!"13@8D:'1-(#=@#,E>>2=%$&H@H%$/9G@=&>0@F#FF8F104HGD9;CD/+8!:"=
@r4483
NCNAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTNTATCGTT
+
!?<-=&/2%(@.#=*2GB@99-$DF!!G6'<G66:6""$+E0-B)E%HD*;D&G1;./%<;#)#D6='$"B<47(=>G'FA@*$4-85685@F>3@G?"H#,$*94!(<E#,$3
@r4484
TGGGGTGNATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACG
+
/!%&GB'87/90#D=&A=8G<:H-C=</.B@803B&2':FH::)/%C"/0#&:<ED%!G7!)$0:3.65A(-*7;@<<$8"#$+.<%G1+*?:'9/<=C,.B:5)
@r4485
TAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGNAGGNTGTGGAAG
+
5*-B->"D9$7=:2+9-=/*;562H0G'6H=4=G8#3$(=@'-8@:)@*B
@r4486
NNAGCCTACACGCATCCTGCTGGTTGACNGGCCTATTACCACAAAGCCATTCCCGGNAAG
+
*%!*)&$+*(*!*!)"'&('&("&)*#'*()%#"!#$##(!)("$+*!"&#""#)$*($)
@r4487
AAGCCAGAACNCCCCGTATACAGACAACGGATAACGGTAAGCAG
+
C?@3A.=<F:==*A7;>C42/H29#53D55=+A=9>$!@F,,#<
@r4488
AGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCNTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGG
+
/A?C'H&%#732&H:1*<C1A4"=#*(6!>=.H'F+=7='&#4*7$>%=G5/88$#!H99H1E&343A7/E7-F@C*5)>*E+"?5&$<,8&"+C'-%64E@C67+0>55=HB?8B'5E,!!!7*9$%0(?438=2&>=&.,<'-?C+!8''(-2=4)2/3"((=F.8#!5H/C4";9='8.;!6,@@3(8D8A24F;7+.!)9D77;5=$BE%H2,0/9==AG:76(=<C761F#(:
@r4489
TAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTC
+
0AB/!*E7.5>.@C'+EEBG6!?8"B-79%)6C:+:'@>,&-7&(F=,G97;28C'GH-3/>9H&1$*F>!91C=*0G'/F9&!GA-568&?',&1'$
@r4490
GGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATG
+
70.9>+3/041F<B**%A-1?#BH4$"EA#E.>=+-<B:!0+,DA2D0#8-G.6D?C
@r4491
GTAACTGGCTGAACACACCGTNGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTNGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGAT
+
089H:,#20,;7%458)2+D<9*AB;<-!BB7'-&;9>F>+;45E<8D-*(5=D+=A3,FCD>1:<1BC<4%8-FHB?0,).+1G06C$A@*"#!4'D?1+"<&@:,3>!H0#%6/5&%&6/AC';FD,F&B9/+&:,@"H@#&2@
@r4492
CTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCNGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGACTTGGGGCGACATTGTCA
+
5D5B+'+H0F059?''"A4":,!AB'>9'$#>>4+1%)H+@22.'D:/%3:;96,24EF34";9%;%).GC9:;1G"?42%6E/%6)F"0,"3)08(1@#>=8E$C'D?*BF9>?4)08H:3
@r4493
GAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTA
+
H-/H85/3/6+4(5HFCC6)CF7B5!''-=49$'#F%B6C+:1B9F">00"(7."'9==0:E5F31@;8F/!(@;>+.'"<E@#1/%+A8(5142"'!?!/+3;GD+G9'2F;2%"!<B>7.=78)5#A>'-&3"4(#G2;(,4/878535G0E">
@r4494
CGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGNTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGG
+
'G7%('A:8@3*&##(DA)"!,1/#FB1(A/6G)<$4GH)/CE2)":%8G>+70$<")18C.<"4#A-,.-1A<%6E@92EG-2%F:81+'F=2F=.:F!"+)&;C&7D8B=E85C<G@A0!(<15+:1?D+<2%G<AG%:%?!&
@r4495
CCNNCNNNGCANNNACGAGNNCNGNAANNGCANNAGCGNNAGGNGNGNNNTNCCNNNNNGCNTNAATACNANTAGNGGTNGNNANAATCNGNGNNNNCNATGTANNNGCGNTNNCNCCTTNNNGNCGNAGCTNNNN
+
"!""!!"!##$#"!!#$#$#$#$!#$$#$$##!"""#$"!!""!#""#""$!#$$$!#!""""!!#$###$!$#$"#"#""!!$!#!##!$!###$!"$!##"$$!"$##!$!"!!"!"!#"$#$$#$"#$!$"$#
@r4496
NNTGACCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCNGATACAGGGCTTGATAATNATTTTCTGAATACATT
+
(&!+!!(*%(!!*$"%(+#)"'"%#)*&!"!!&&%!#'&'%'()(('')%'!)**+'(!)()*$%)&*)'#)#"($!"$'+)*'+&"'+$*+'%&*%+(")&%*&$(
@r4497
GTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGG
+
=115C,@9%6G(A6@>:$;1"&?C70*3?:))8F2("=8&AF:7D=!D#)G:&H+!C!A2&)
@r4498
AGTCCACGTATGACCCGACCCACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGG
+
%9H<1=;B1C3((=3$)';77#0!?50;63:#*;6C2.8?1(=?.C++><2?0")2<./<39@!?:9/1$6,G@9%;4,85<///:)EC"=D
@r4499
CNGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCGACGACGATGAACAGACGCNGCTGCGTGTGGATGAGG
+
*!?4C>@/2)@<"35C>/8(A3.=(2()6D/+>C#G*D"A6H4*B(C3;.,D@%6>!5<F2A:4H4DF(/1=%*-;;H*.$6F%>,*""05>!/#*A28$!#0?.1*/(8!2+>-!=1BE)2=+92<056&>18<$C-.>%'6$H@E>C"0?6H4&F1..#-*:4?A;F5H#::&*C,(E.&,D')"A(!%;5=4&2@ED80)C<H/,(0EG*'*/$77/C.3>61'EF-(8/=CF$."+H"0&1*'C
@r4500
TTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTNTGATGATT
+
ABF)2:8H7H7<8F=2,<3,9-?F)>%;'%&!B=;5:E"*A77<@<.G%B49//CA-!3?F>-;%$
@r4501
ATGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAANAAGATGATGGCTAAACCAGCGCGAAGACG
+
&+)!!+#%+*)("""+%"%*"%%$%*#'&"$(*##*$+($'"$#!($"+#"**)*)%&!"*"'()&!'")$(()###"&+%)!&&**%
@r4502
GTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGNCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCNGNTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTA
+
BAABE;D&.C(E#D%E81G4?'-H?-9.%*9(&8=G09-<.&>7-&3:;,::)(3F&*E%8F?E:@?<9B<":=2+3G'54$3>?$8'38E+$-8H-02'?4?.>H42@BB4*"%?$-EF6A#F9C)&:<B<@4B*6:&%H<2-F&0A3=+$(&7B(0,+G08AB6E>""G3B)#*$%1>)>;9"H#<83-#1(-F*)4,>31G%%%-$C-2G+2#?,+(6!CG!,;#FH%E
@r4503
CATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGG
+
(8627%/'BF.:"#0'8'E!)4'=$5"F#*#6'1"$D"C1
@r4504
NNTTCNCNCTTTCTGAACTGTCAGCCCTGCAGCCCATTGAGCATCTCGCCCTGA
+
#&%%)#'&*$+%&%$"!!)&+&)#((*#(*'$"&#+(+"*%+%*!)&''((%"'
@r4505
NTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCT
+
"+!*&#*!!(*!&!$+%)(#'"'&!"+$$#!%(&&')+$(('$+()*)&*+'")$#(
@r4506
CCCGGGAGCACTTNTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCANAC
+
"<(F21(?B&,>8545G<%0FCB336"6#;)"2'(0AA.&<+EE=GC%$3H'$&F>
@r4507
CCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGCAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAGACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCA
+
A.<:40+AD'@4*4/13!*%1D0!09+A5F9!:A;+D7<.0$(-6*4)2894$05"0EE4AF.-@6?'?"<9C'B97:BH50!+HH=*:8-5!D#!A@7%F*-G@%+'>'%"F--')%AD#@)+2:3:(@#="C%E>.)889))("8'-*$,0:#*7%H&(";C0/<H&C;4,:$D?B+$G2&-)(.+#.)2/2='6(!3BH7/$D@
@r4508
TGATTAACGGAANTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAATCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCNCTNATAAGCCATCAATCATNATTTGCTCATGGTNTCCACGTACAGCTCTGAACC
+
:+8=%),G,/-2@H.524B?D'.>/0<E4C8++&'$/9;6+02H4.&.69!7)*!:>D$$1DF=$?+/!@;!#5/!=4/)B%C%'"17$B$*+H80D=/F''CBD4/%7%#&>EA(3)2C*5?6"(=@4=EG((16/;;&A*!=:6@'E75C$)D*,'+!'3$D!G/G$&!*E'
@r4509
NNNNAGNNAGGGNNNGANCGNTATGNAAANACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTNC
+
"$$!"#'"''(*!"$%*!("'"*&#"'&#%'+)!(!'))*%("#$&*&)"%)!+'$&'!%%!)!&#'%)%%)&!$&&(%'&#
@r4510
CGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTNCAGATTAATGACACCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCNCGTGAGTTANCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGNGGAAATGTGTTTTACAGCGTGA
+
,A#("##!HC'&D>83=-1)#68*B:G(,9485/3-+,3&8G$=/%5BEA!.:>6,/8?:3=4'B297E8H,=8CG'?B6"*'/2A8464B6#5D(2*/16+!2E171/H14+4@/"G(57=;.><B!<,@,:$"'>**:H:&!E!F07C*"H?GF)+)+6;.B1*/)F"(%0/C5!3,=0-)#'0)GDF-,8<H(+$@E3HF9$B4(;H(;?9FE<$A@!&4)A4,7#G080F:0(!GBB:?;@/%@))-@6>AB
@r4511
GNTGGTCAGGTAGTGGTGATTGGTCGCTGATGCAAAATGTTNTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTNATGGAGCGTGAGGAATGGGTAAATGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCNCGCAGTTGCTGAGTGTNATCGATG
+
*%++"+$#(%)*%)#!$"!"&$*$"#$("+"#&!&$')&%)#'&*'%+%%%*!)!!(+&&*!)"**!%&'+'$!$#)%$"##$((!(%$%!+!(+#*%'"%)"&'($!)%#((#(!#+%##$*&+"++%+)"&%%&&#!'*(*""*)!+*!)+!$**(*$$"'**""!*#+&
@r4512
GATGAAAGTCCGGCATCTCAATGCCCGCCAGATGATAAGCATCCCGGAACAGTG
+
/)5?-CB.!C:2GF2>8:B"-+:(.5>&5316"'C0H..<.=@!?7:@36:C5:
@r4513
TCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGC
+
E0%"F:G=/-587?D(F4/C""%4C7!:7<337)%HB3;D>'$,!0GA5'&%0+:"<H863(45H27$4F'HF6<
@r4514
GACCGGCGCTGCGGCGTAATACGCGGAAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATGGCTGACTGCGTATCCAGCTNACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTC
+
(#E:,-08:E&5)D$/H6;H4<98,@AH*<"B8:*H$'*7F!6*%<*BF1;,'++>C+)$)>H>>*-)$"0D(,#+*%E)@#>9F4!3@4,<-&2&G7G<"&",40C+:"(AG%)703'CF8(A=49,1-H;D22G<5?+16'&C24>F4H$$1")7G<6.1H'@'%=($)=G#7A)D>)*<3<D'37<16AE50#
@r4515
AATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGAT
+
86+,2-9?@E/59)->G22C".>?DHH7&B6<)-5H+E:$9B.;02&F0??;$6=#4A>%"=
@r4516
TCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGC
+
.G+!E8>!',")C%50>)C?&"F<8>G)85@<7#:16?C/+525+FH#)!>%2($D9>:B&D*-=;%(!$,GDA.A*'+D(5*6E?A$@>?8G:HHH5<=4&>,-.!H25#GC5>'@(%.0?-H:2*:&642
@r4517
GACGCAGGCATTATGCTCCCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTNTCGCNAAATTTAAGATACTGCTCCTCCCCGCAATGCNGGCAGGCA
+
E5,9D=#@9)6A/:A#&>4=C6)%$'(4?C)1#HA38).!A15<;-7<3#='+CHFE%6#(@4*#75#*?>D1,%6@6$6"0$F>/&?/2!@C7"(;-@34!8;?$;<%4':@%8).8+=.?/6>%?
@r4518
NANTCNNGNNTNNNANACNTCGGANCATNACANCAATGCCAATCAACTCACTAATGTATGGGAATTGTTTTGNTGTAACCACATACTTCCTG
+
$(!)#!%'""##!$%#)"!(!$)$$$*%$(&'$')*&#!+)#'!'**&!*&%*%%(&'$&%++'$+)%))#&"!&#"*)&$$++%+(""#"$
@r4519
GCCGCCATTCTCGCGNCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTG
+
%A1C9!$AF%5;.8#G(6H2H40GD:2E9G$G##'(*7"D%A50-8<#=(H3506,?%:$5"3?--FGE9+#B*:4F97A>"?13&B%
@r4520
CCTGTGCTGTTTTGGTTCATCAGTGCCGNATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGCTTTGCAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACANAGCTCCCGGCGTTTCGTCAGA
+
D21".<EGA8/GA5HBD7&8,:G7>4<'@71>@<B=&'<F0"19A&>E@7!$&*.@*,C+0(3E'D-!GA/F267(?&G.=$9?7@$3&';.$:1"B;,($*0713<3+79C;<1$>D4./>"@F&8E%+"2D/?A07!!":/"F:*9&)4:6+4+;/0D;-'(G.C+?H70D+H4,;*@%*29H70<-/FB8,A%*9*6@:7;GB>'/;/5?HA9?*1C)("0B>#G=*/?$!!49)FG>-:%65-/@C,;D9:>=/?&(B**<.D-4#,</D
@r4521
NGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTT
+
!1".:30'1F#,$:*4%+=$F)G#/75$1#E#''<?DCAC<E-";,6!6AC&%G@A4$&*A0#;.653)A4>
@r4522
TTGCTGCACNATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAATAATTTTTTCCTGCCATCCACCC
+
EB:-GF4$/4'"*/0&>0=H)E25B&0H*0+@#0+4-40,?B&?!>G0@3A'H21'=@'G-8?/'E#<C'/%%*+&@C9B(10A1$H:3<G*@0C7,F$D:GB(-:<*F%F@+**H+"E;"7!5,@'-E(;H!!27-BG"!C,&='02=2,"2(%9/3(>#B*.)
@r4523
CGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTGTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGT
+
')8*F5/(';-*"-!BAA45+%CD+E">#"G:)85!!2H;&5BB9.9=B:9AC7CH5121=0*-,#3H@)DD9D1#@H6-4/?F:E"DC*4;@-3HBHG($'41/F<#@6.28H202:<8>47?(+D%*B&GF+:##%9.2@F.8B@8)*<&A=692'(*(6'ADB(H2AE.A6/+',&%39C1#9<95D)+*=B+6<8"B$+#A1?=E@)'(B.90#H#3-4>/;@H0?F2<+G'9.!A
@r4524
ACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAG
+
>;<4/)?(&(GF>=!3>@5&?4;)C%E2%$+G,2#7:EG3+)@<&'11;2(DF2+4@9=0D$#F6)9!*A-9)6E"%*BD.164!A??A@@
@r4525
GTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCNCA
+
@B;E4-12,,:=:.&A'079<8(G@,,H/@-5C"'E<E9!33&(>&C5A3.EH=,')F,D1<0F"0&C
@r4526
ACACAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATA
+
()&#)+%+""(%'%!+'(&$+$%!"#(++)+%*"%&&(!(')*+')')%$*'()&$+
@r4527
CGCTTCAGAAGTTCACNACGTGATAGCAAAACCCCGCTCGGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCNTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTCCGAGAACGACCCCAGAACCCTGTTTGAATTCACTTCCGG
+
=>FBB%5?A,!F0#:C9+&H.5<+"#3FFAE:1A1G6+,C:1">A!?E#25=B&96.>!:,">@:B%#/A-+BH>5*5"241!*2*8$G8:?6-)5H1$6C'CC'7A*5->7G5!DD:$B,..+.7'7H)+4A@+$$3G#<".)H:/9<#F#",64'**/#6$87/).80):B&CG7!:>+=G(=%BC2866
@r4528
AACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATTGTGTTATTCCC
+
/*"D>*B$'A!!E/A?9F7%>D:8D!F#8*9*HC=3/,F24?.%9"&C+9@794HA-G==!35A49D1&@';H37#HH/>#:HH49*:,+;>59B<61*FB+,.-:H""5:&,;2'-*&+00B3@B&(*!0&89EH,@&>$
@r4529
TATAGCCTGGTGGTTCAGGCGGCGCATTTTNATTGCTGTG
+
=68;7#04+9B?4*/-7H+?0#"0+H'E$%-,H15B?:8'
@r4530
AGAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCA
+
'"1F7$7%3@&<36&+<2#0;,@(.F<@A:&"D<-D-E3(>?2F0#<'.HB8D
@r4531
GNNNNTANNNGGCNNNANANTAANNGCNANAATNNGANNATACANANNANGNCANNNNTNNNATNNTNNCTTNNCTGANNNNANANNNCCTNNTCNNNCGTNNNNACGNNCNNANGNANNGNCGTCAAAGANNCCNTNCCN
+
#!$"!"""$#""$$#$$#"###$#"$#"##"!!$$""$##$""$$#"$!!#$""""#$!!"!#$""!#"!"""!##""$$###!$"!""##"#""!!"""$"$"#$"#$!#!$$!!"#!!"!!$""#"#!"$!!!#$#$""
@r4532
TATTTTGACTGTTAGTGACCTGTTCGTTGCAACAANTTGATAAGCANTGCTTTTTTATAATGCCAACTTAGTATAAAAAAGNTGANCGAGAAACGTAAAATGATATAAATATCAATATATTAAA
+
+$%"&%+!#%%*!%+(((+#+#!!))%'#'#"*+#"$$'$!%+#()+'"#$)*##)%"$#'!")+$)'+%$"#(#"$*))(!("&*#")&*+'("("#*+!"#"%$+"#+%($#'$!(#&+&")
@r4533
TTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTG
+
8C#D5!!64D:()@04!@"+.8HC7=1?BG&%2"'1'F0@B7C(62()4G0G(2
@r4534
TTAGTCCAGAGCAAATATGCTGACGTCCTGCCANCGGAGAAACTAACGACATTTA
+
B%+'7)!20C@$D33:E2E*G:3H(:"",/0",<.=H*&/C.G!/!D458A?F&4
@r4535
ATATGAAAAGCAAAATNATCAGGGAGCTACAGGCTCCTTT
+
&$;G,*<*;,0$"()/B+E#+!*36D7#(#29H%+@4'3C
@r4536
AGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCANACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCC
+
4F'!C6(4-D?93-!E7F6&7B7A1*8=!31,&,%D*=5B!*#@"*E.%A236H@(C($!483H01,A0?9)0!F5)=E%50!>"!?0,%D$&;8@"B#
@r4537
CAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGC
+
9,C>#0C(#1D+.,-/3/-&E?>E//68.&>9(/<!EAG15H)1&!,50C9#1:/6/,*13'3&:."H9F)+F(;:'GD-<-:'-216
@r4538
CGNCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATT
+
H:*%7>G88?G;D"E!-@3CB%$<(7(D$6-=/0$/E%;:A;HEG-D">D31GH7@
@r4539
GGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGNATCAGGTACGGNTTNCCGGGCGGGACGTCAGCAGGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCTTATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTC
+
&.>A*A"D&F%!4*)C'C3;5A=3)=F7:@+;9;*=*#,:-7.2%?4/.;,2+%CE$:F8H96?+1/5C%(.F2$+!7,F.E4,CDD2)1;/$8B,>,+>7H,.//@8F1G<6H3(+1BGB>.%F/#=0H5@2*4;6C2'#HA(6&FAE=;<3#5.9H+E@+62#%A#F?)2C7"%BD+(=!@&&*&8*<.GGG(77G)7
@r4540
CCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGG
+
'8.(H&C58;4&>B>D2EAE/"<9#H=FG->B5H+E#+B:,E:/G/H!
@r4541
TAACGCNTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGT
+
C#>,)135"0*3)F=$8!%&.C.=G068B/<51?%A4+A&D!23>DE";D8-E
@r4542
NGTTNGTNGAAGACACNTCGGCCGAGGNANTTTNTTCCGCT
+
$%)%""*!%(")((&"%"&($$'*!%('(((&)###+)!*&
@r4543
GTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTCGGGGAATTTTCACTCCCCTCAGAACATANCATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACT
+
AD-1$1F5EG*:*1D4:F!=B"+#?=&/(B'<%"9)70G:%8$+8&@5*@C#+(>B)F:$;))B/2C,6A%-6$<&)HG?%D0%/83;E18;;GE/?#1C'3.@H7-5$1G7&.61<-840$",&4'$3-C:1&EB=+F.+...<-")'H$<8D).<*(,+!G3/)*/+=:!"=%%0H.51D,-45.
@r4544
GGGGGCTCATGCTCACAGTCTGNGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACANGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAAC
+
A$2C>74<$@)E:!4#,F9(=-%&9#2'#2642-&;96E&C91D*@+@/&&>%:D&97)5:&B$5&!;$+'?()>538FD56A%)+#5$F.>*(E1H.66$$GG4
@r4545
GTCCGGCTGGGAGGCGCAAACGTACCGCACCTGATGCCGGGTGAC
+
)@?/)@*ADH1A*&=C%D)A@B6<81B@?HF=B3<7C+(.<DC?9
@r4546
NGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGA
+
#=58$,#2D/,28>-$:7D5$=08,E!#!<)".4H<,%&7?E0)3*-)'9-=:'D.5H/4%,>77E/%)#B"GG)!"97B/'H861)/A@>E5$,
@r4547
ACATTGTCATCACATGCANGAACCATGATTGCAATCCTGATTGCTGCCTTGANGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGTTTGGAGCTTTGTTTTTCTGCGGGTTATTNCTTCTTTCCANCATAAGCG
+
%5:(A2,#656(68;A6.)(#4B-5=&<!F&2H0-?8*>%9%%C$$F1<1D-2@;,H%242C)F&?=*=+3=$.&4-76#'0!?/-)C$<#@.FF&1*#6<+@%=!,)'08A.8/214*55H<(@;/GA%43:#H6%%64$.*%!G0%76$F?%>#!:-)=H@FE%<4'4/D8(#@?GB+B1E)70>79.GA#4>H,=!
@r4548
NTTTCACAGCTATTTGAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAG
+
"0FG:B?;$5D$!4%$1!5#2#".FA+*<@7)>/<&>C@?5."E$(3A/E$5$0&*64C3G;=F%<=-3@<'=@"%3ED$+.>AH*'!
@r4549
TGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCT
+
1;/@0$C<2"/H'D*E21@-FD"F#>E'09DC66,E=)-"#'G5/1-')&.;C-HC@EA
@r4550
ATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTAT
+
G@7,90&*#7*F,+8H04EC8',#FC0%0+#2'+DG##6/H)'*4!@C2<?C."3G77(/#,5:8&8!#*+2DB45%6H-D5$&'
@r4551
TTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTNATTTAGCATGATACAATATGACAATAAA
+
>(AA17:!>*:5-G6'$90,4@?*,;57&&".$!20C&A5F<B:C.&.8#;"6,<+!2-.2#.02!#/%+G.D$(!#"+=);(340<92
@r4552
GTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGANGGTGGACA
+
+"5/$.'?"+0(-E2G:@<:?D1H0.E6+$4B+=#!"/&F%D=F>87':F7G6
@r4553
CGTTTGCTCAGTTGTTCAGGAATATGGTGCANCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCAC
+
+(&%**'&#"**$%*#)("()%+&+'((&&%+)!!!"%"'#&#"#!*&"!&!**(#%**+(!**)(%***##$%
@r4554
GNNACACNCCAACCNNGANGCCATTGCAGGGTGGCCTGTTGNTGGCTGCCNTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCNAAGAATGGATCAAACNCTTATGGCTATCCAGACTAAATTCA
+
*!"$((%"*#*!%)"%##%+))$'''**!+*'*!!"**"$(%"$""**$&!!+!%*#$"+&("+(%#+$("%&$(*(!!##"($##%+%%$*$+(%$'#(+($()&&"*%*#+(%("'$!%)&"'*"!#&*++$'(+"+(!**"%'++"&!(!"%"$+$!""$('!+'""+&!"*%)(('
@r4555
GCCGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACNCCGGGCCCGCAGAGCCTGTTTC
+
'#&E7.=:"1%+<<;@=&#(0F9%,F0+A,:*$3G*),<5CA8=!(=21H.D$?HD/7#64&F&!*H@??;:8'B"0C
@r4556
CGGGTAAAGTTGNGCAACAGGGCTGCATCCACACTTNCACTCGGTGGGTTCCACGACCGCAGCTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCC
+
F(*#$2E.F>D7>=-8#>G?(!G-$(3%/F-1;FC>6-2HA2$*#6C$DG22C@!8(7')5&9'='.=D4597409*/-'C0H<77$4$C!!;>/)-*<;>#,&B5:=>A<*>+E@>+.F;:1>=:5)%1'4'2
@r4557
CGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAAC
+
(?F@8@)C=<5*+F+83B,+/+H5.0;&7$>AE4?>2<HE*>&*>#"EG);%8E6'9%0;>9,1D&'()7
@r4558
GTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATG
+
91A<E6;+#E2='4,G*)>A((+>0E87;G8F0+D4E,$F5*G;'<.'/@1@?G?H>"@(<E.<E@:;&0B>CE-2*G;
@r4559
AAAATATCAGCTATGCCNGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTG
+
A328@#88#7D"92<0)#-HF"5)%<4,+6:6,.!2C)(E>1'G21.H/+'21+/,7'D1@,!8%';19@G52-8@5
@r4560
CAACGGCTGCGGCACCTCAACTCCGATTTAATGANCGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCG
+
$$(B%'H"DA<<**2+2>51")F$@&<G1+E9'@13:4FG=0&-)%*,;5*21F1,()@G5.".@,);A6;+2!+0',9!2!.B&-'H$+?6"7,
@r4561
TGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACNCGCACGGTGAAAGTCNCCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAG
+
A$$2)7*E+G.!?G;8#3$'099=)"<A.<'#FD;<A'0#&A%E</2&E-$7H,>/C8D>6D'))"'.(((E$-;B%4*(5F.'8,D0D>9+;D"==0@1*13A@7%4,'75
@r4562
TGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTT
+
>3>?B/#9H6FB-;&$H04!A19E*:',.7*/'(8#G&#,&'C%6-=5B>0@C$+#.B<;"*7,8/""(H
@r4563
ATGTGGNCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTTACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGG
+
&99-A+).0D<60>4A&18;0(#HC'!*@30*B5#1H7G:$D>@5H<9''$71%<'$>2/:2'A-/A:3H2&*9&?(73.24)78@#""3,%12?#(;>'2@04+"1'C;"4,!(,.:43)AC@9$$?519)0!'?08CHD#GB=2E12)@E!;H-(?-;8$5##-A=':14<"+2(%#G>1?&,*)24C/)&=';.5;C>/948*F/>EB=G5@B!D*H2-H8$EA?:58&4,)A
@r4564
GCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAG
+
<))>"D+16(-B7182E63FE!83/7):6>H2'GA$/6?G'=*065B(62%B+C9&%DEFH?*BG7E0=-$6'E34?#4.)3=D<='@#.7"1?'($BB?>'4H91
@r4565
AAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGG
+
97@+392!D"'?<>$&4="/:&/=-#?#D&>@"E<=5:D2H;;/A,F#>&6',45D3F#>7>6C;'+G0;D?G=0F!0(*&&&.<'<
@r4566
NTTCGCGGAAGTAAGCATACTGTCAGCGGCAGGACAACGTATTCGATG
+
")'$#++*#*&'!*(&)#'")##$*('##&"!&+!)"'%$'%%%(+%!
@r4567
TACTGGATAGCCGCCAGTGTCAGCATATCANANCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGG
+
$&#+"(*"'*(!%*$+#*#&)#&!#"+')+#$**$$+(#&%(((%##($+&$!!"#$''"*$+(%'&(+#"%#++##"(
@r4568
ACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATACTGC
+
=#2#4,4?>8<#$(.0#:E6@62B!4$/25>88'"EC%//:FH<"%H8&??
@r4569
GTTGNATNAAANTNTTTNGATATNCNGNNNCTCGATGGAAATACTTTTCTCTTTATCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTNAGTTGAAGATATTAAGAACAGCCTTG
+
%"%%!$(&!**"&#%$"(!&**)!'!#&!"&#(*+!!*#"*+'!")&%$%*'+$""#+!%#%$)'!"%*#"$"&$#*+#&"*%+#%!(&%*"%%$!%)#("%**)#$*%&%%!$((!'!%*%(!'*#&$)+'+
@r4570
GGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCC
+
A>=CG=0/FH?EG9$9?:'12"9-98+F%8BGD?1:=A17-+C$,.;-H=@"HDD:!E.B?(>E5?3%=>171!C=8$#<+D86@=E=47<72+8$,'FD5!+?F39844"$,C*
@r4571
AGTGTAAGGGATGTTTATGACGAGCAAAGAANCCTTTACC
+
'2<5"'.*;H)5&$+*7)@96C!?9*(G1;1,+A-85H@E
@r4572
CCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTNTGGACAGGACCAGCATACGATCTGCCGTCTGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGC
+
C>-)%"H>E2?=)!*,B%<(#AD67/D!.D6-2.!G6:H*#/&.$H?$@3#-ED;.95:<$,',;3!<3(@.?1B07!!",1/%$>,.%.(6&CF#'(@(<G"+/;%@@G?-**+*,>B7D,#>F<+99FCCA#;!$?DEE+1.!@A(#42>:2CD6!.5?*'63?DF:=?F"48/H1B53@D932'.'8A4!7C?
@r4573
GCTNATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCA
+
%F25B4()&>$6-.#*$*E'1@F/%57E5>H,F!'#&9E9>@'A,"4'1A"
@r4574
GCACACCACGCATTGCTTGTGAATCTTGCGTTCNTTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGA
+
@9)</C?=?-;$=&E>/>)7G9$#+&$&>9&',=861A*>,)1@:;%3BG#;EC2H!+8B'&++671$FBAC8F=B'4G6E.08*H><,'C'8-A?
@r4575
CTNGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCNCGGTGGTTTCGAGGCCATAAA
+
9,=/E21)D5;$G>#63=/2DF(*'-0!3.2()0-+8@!%#2F%./4F$868F46&64G;@6(*5<*7GD#
@r4576
GTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGANAAACTA
+
)"'+)*$$""%&)'#'!!&)$*$%"%+#'("$*))"%(()($!%!!&*)"%)%&'$&$!#%!"""
@r4577
CATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAGAGATGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTTCCAAC
+
&$+*+*#$#+)*)'!$($+$'%&#)'*+#&&##'*"$#+)!$+$((#$))&'&)'!$+&++&%!#'$*(%$!'*%#'($#%*)+%*+*"$!$*('#(%#"!&)+()$
@r4578
CCACACAGCTCCCGGCGTTTCGTCAGANACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCG
+
%415GE:&-7.6%)47)04(%@*G,-:@+$)$!!4:7=>F'$<CADG;F3<'3E:A'37C,6).@/@1E(D/D03%A.2?&=-1$<A>#;*C8%=
@r4579
NGACGTTTTTATCCGGAAACTGCTGTCTGGCTTNTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCCGCAAGCATAAGCACACAGAATATGAAGCCCGCT
+
(2GD1E?24@82'<#H2,2?*F'F:)C(5.F,!#.&A$1=E!>287F3%-BH16?5&2$7'@?=F8!.1@)13F#1A2"C(8C$-D2$%0<8&4%"8/E,E%/9?>5/+B+C6=0A$GG$+4:)C53H$-286.43;H88<:76!$6%4
@r4580
AGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATNCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGC
+
9'B.#6>)651?;7>(5EF$4/.$*00>,-F>"+1!";5F.$'1G4'C1A95(,#0,7&H+G>$@BE21(;$;-:+/#*!.1?1D+96=AGH4G:;:=F@00H(<&35,&;?3.-6/-H%@4=',G;#9%'>*+<-+9/F:D)D;8*3'"DG.G9@6C#;1FAH1E!1%$=12<#A#1'(:%)B)88)9A336)A!5&-3-=$&@20$5/'5*06&498)G'79C:+&*'08H+$(8*:7E=C>'-;8&'8><<4A
@r4581
ACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCNATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATGCCTCTGAAAAAATCTTCCGAGTTNGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTNAAATCTA
+
5,:7"G->,0H9G8#8;#/B%;&GBF&9A:@<4<+CF8,2+=;E/3@:D?H4!7<'!1$+>=4"/E)B9>1D0?-D0>3*=E&-D2')91#$4-./D;.$#2+<5F3<;FC?,60;>74'E2D2)06)5>@%(>?)2/F+@9$H2@F?)6:4F"&'(7:9=E'8?@#,69B3A73?4
@r4582
ANTGTCTTGNCGTTNCTTANCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGNTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGG
+
""$&$*(#&%'&)#%**%($+&!!!!%$*"())%&(++("('!&$$&)%#)+(('$#(*+#(''*%($#*'$%'!'("$+!()((++#*'+'&($#&'(+)!(&+"$'!))%*
@r4583
NNNNNNANGCACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACG
+
#"#&!"('&"+#%'&"%!""$'+&!'''+!'('!'#'!&&+('#'"$'('&'#'"##"%!#%")+)%(+)!(+$!(*$'*#+(&)(
@r4584
ACCACTGATGAGCGAATGCAGGGTGATACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTT
+
,BE)*%4+(B8*-!<5.E>#D,H2H(,*D=B.8F%?4@.1G(9>A7F@,&:$H*C8C>9FH?@5+C2$@;1!@G%#6%6A:6C;1
@r4585
NNNTCTTTNNANTNNCTTGNANNNNTTNTANNATNCNTNGCNCGAGNAANNTGCTGGNGNNTNTNNNTNAANNNNAGNCNGNNNTNCGNNTGCTNCNANNNGANTANNNNNCTNCNNAANGATNNGNCNNNNNANNGNTGGCNANCCNGTATNNNNGNNNNACTTTNNGCGNCNCCTNNNCNT
+
###$#"$$$!#!#""$$#$"##$!$$!!#$!""#!"#!##!#$!$!!"!!!##"!$$#$#!$"#!""#"#"!#!"""!!!#$!#!"$$"!""##!$$$!!$"####!#"$!$$##$"!#"$$#!"#""!!"$##$$!!#$#"#!!#$""#!!!!$#"!#"!"#"!!!"!$#"$$#"$#$!$#!
@r4586
ACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTAC
+
.6,>B+)&..B>03@!!:CC4/$+4.&*F830**55&1!@F)H><HC1*"C&78,:5'9
@r4587
TGNCGGGCGCTGGTTATGGTCAGNTCGAGCATAAGGCTGACAGCCTGATT
+
113#4F;C,*/?72('!<8:)!@'+A'$B%7)(D'E:>(E7"):5?-F&>
@r4588
AAAGAAANAGTTGAGNCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGNGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTT
+
%(!*#'&%$%"())&&*+*"*'$$!!$'#(+*$"!"#("#**$#)"$*+)'**$)(!"!)""'")+%+&!&"&"!$'!$&"!%%&&++!'!#&'')!'+$+""+$#!*+&+#%!%"#%
@r4589
NTNTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGANGATACGTCGAA
+
#*+*)+!&**"+#)&)(''%!'##%%"%"##!%(*"*)!!%)&*')!%"#(*'
@r4590
AGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGG
+
?5>47.H:$>#(&90C*'D)0)(G;5?/$+:58+"%3&@&G-7B$60#7=%-8#7
@r4591
TTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACANATNCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATNTACTCCAA
+
-E5A5$C3:@1;-<:#8)=*F=*D'8'51)(;($?:4AB3&-?!A?18>/A%HA15%BE,9*?A)42,7BD"<),/9%9B>)'",!@87=E$:E$?986:!)82@3:>41(!)=G'A7>10(!/6A+/<C2F-49<95GD$E'H#A<:)E2/:!E%!H*/,'1A&(F%()E>FCHH-4=7"83F111=8:.@,/F'!457-*1'6>
@r4592
ATNTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCAT
+
&)(G(=BD4!+/9')7GC>!3>&FD,-=#-:4"E2(87>.<A.$#)D.@-5=H5%144)B&0/C(<!)=4,9!G1,61%/&3H*!6059'70667$+=F/;BE(94'?0):B'G.-9355$38EAF".9%0+6@F3.H/599=H&!!)D43C=E-H2-C#94#1'D(?=</0>2?@/&0;C@;0::?E>4<D72A4=D!?$="-H@'CE>.5.B8F###
@r4593
AGNGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAAT
+
(!",A!53;A1:((&H3@/?2G:F=*"%@7,30C>%(B)86#8E.*<G.EH=9HC)5))!&1@E39&*G)&)5)B*-/!0+.6?2>"@--,E<'!03
@r4594
CTCACGCCCTTCACCNCCTTCGGTGTGTCNCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTNAGGTGCTGCACCGCTGGCGGNGTGACACCATTCACCGTGCCACTCTNTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGNTGCA
+
+.+6(G@$F.;6800$+A"7'14%CG<4:9*CG95<.=>8*3:<6H4B?#2?46C!B8H7%-58BB">$3'7'!,>'64.>A*'7G.<"2)/#'75G!"F9!*HF*?%17B58A7G=73A0+@82BB=7=.D-43>H>&B4H15#D0&G!<897#?41*:!BA!,18E$&$C9@988C<28F2-.;!
@r4595
GAATCCCCGATCATCNATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACG
+
4E:E)8EH>"7.=#"!:%!@,:'!9#/)?EB1:G%5!9&07B:@'3%,96=E%H!5785AB>3D+CCA6%
@r4596
TTCCGGCGATGANGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGANCATGGGC
+
%";@6-E;:?647=;;9/?>F8>2#9>=#=.0"8&A49"?'3!!'?#'<?0<9#G"+B=&8BF;G5+AD:=A@<3B/A'F-;D$'D7*53"9B4
@r4597
AGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCNGACACCATGGCATNACAGTATCGTGATGACAGAGGCAGGG
+
D/*;,=>)-B-=5D-/&'9''+<?./*1C-/@<4?%/5"'?,#"G>*3HF/F.C)E:)@*:6G%H#-8@5(H17->9E":'=&)"@9D&=6?@H;G0/(BF*>F$*$7?F:G*=D:*CD0";?6B;?%0?.DE02!#%B,"%GD.H+;,,@0$D:3G$4ADC(>
@r4598
GAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACC
+
8+#G.15<$@679(./4#@!D@<-<<';EF7-'(*0!*91+015;%*G<5-<8H+"*2*2A$>'&(A/A"B;E@6<)$?9E:HA9)&D)A
@r4599
GGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGNTC
+
%689D9"/@B&1:.444#10=/#*3&$4'734,9.9*F51+!*H31E&/D"C?4
@r4600
CATCTAACCTNTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATA
+
16!/%.@>;/8(B88&*014F,<*F=9:$E",FDHHH9/CCF<AAG4,@.-"G"<4@G7EB'E68=>36AD<-/-6=@EA,"2C
@r4601
CTNTNCNTTNGGTGTTGTGTGTGAGTTCGACTGGAATGATG
+
!&"&#)&#!+'!+"("+++!$!!)%'#'+'*("(')")#&(
@r4602
GATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACC
+
*7D*90.*(7BG6-0#/*-?1D2>+0%5"9=<H+1E!@'6?!A#=1'@#)*'?1?0&.&!(>)B*F'859?.2;85'
@r4603
GACGAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTNGCAGGTAAAAAGTGC
+
,C!H5-4*<#5.14.*E"94G$(95E-E=-<+%D3?$/-6+D*27B=3H4!8'26#:)&67+4C>;DC3-=(52AGH$3F3D:;&.)5..6#>0C
@r4604
GTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGT
+
"C.!F5=<H%%:/8%<)6H&'H".*(*5+$:B(=#77'BD<,BA)%(19-G!D!(@.@HC)001$B0(+"6C')>$F';!0>
@r4605
CGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTTTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATN
+
+#)"%''*$!)''%++")''($''+%!(""(+)#(#+#&''!&+)"$!!*##)#!*'*&+"!%$()&"%!)+'+++$+$'!"(+((+)''""'&&#"$#*$*#!+%)&*$'&*+%*("
@r4606
NCAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACT
+
!82'47'+'.2F4>62>4C):)CC$56--#<BB.$G@='<!!G1"&<DB/9FH2!C01A.CG?,9@$@>%:0$D-<
@r4607
CGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGT
+
(430B!)0&3H#;",9!F$48=0HF"065*-/%$7@3,()ECD%15*&4*,628,#<E@!2;E/6;CE5!D0*3H*4-'32H61DF:'7$*!2$&<GHG3&83-C?&>8.8C&=.,9#,8#.E<"G><%2./@.*C/7,B9;5G0:+=G$?829?$2.>G>*:"-+!:'<D50;
@r4608
GCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTNCATCANCCAGTCCGGCATCAATGG
+
$#+*)(!)*!*!$(!'(!*('"#%&%'**+(%)")(&"'!((#(+%$'!"$!!!$&!$%**$&')'&+''%'*"#()!$#$*#$#"%%!++!(%"+!%&+
@r4609
GCACGAGAAACGTAAAATGATNCAAATATCAATATATTANATTAGATTTTGCATAAAAAACAGNCTANATAATACTGTAAAACACAACATATGCAGTCACTATGAA
+
6:;-E((7B2/1A8>/)(??G).3EE!(<.C2+A28DB=>:4(<DCD59C.'1&;7D83#.D>7#!+,#1'@=:;D1G<?)DD!7C>-$""%@(E%'.)"6?C:+*
@r4610
TTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCNGCTGGCGCATTGAGCAGTGCAGCGAACT
+
;FG067(A79>D,>(>>6.;C.5E?HD"248+=&5@6>,!8<DF?/88?,B@/='&+66H-$"G?9!@5(1("HDA4C0=0)C@8:=7#&$<"083
@r4611
NGNCGGGTGNNGAGAATNACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGANGACAGNAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCG
+
#(!%"'&"(''(()!)""&+*(&(%'!*!#$)(%)&*%%+%&*##)$%##%%)'+$%#*%&&(+)**+$'+")(#%&$)"#&'*$#'+*('%#"(&(#'!%&!*!*')$""'*))!&)#"
@r4612
CAGGTCGCGGCCGTTNTGACTNATGCAACTGACTCAGCACGCGCCGCC
+
?GB4+@7A1<E008,?&<B5G++E>E1GEC.FEDHF<.?22E;H&>E?
@r4613
TCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGA
+
*4>7@,:B'"898>8#$7)<$<4?B$:+3H9G+5<%D.$)2>-
@r4614
GCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTG
+
3)2?7CE9:&=A=FHE9$3.&A-G;.4H1*+D2,6-&G6&B=@'>**6';56)>99?52$A0G,2(41!+6DG,03?)>4@?3;B7+,&06-'<2!6+8.E>E=3A(22
@r4615
GCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGACAAGC
+
B1"$9?FG#.&,H:F255%$>&(@+G+.-5*5C-<+/0#*F1>>#E#DB#
@r4616
GCACGGCAGAAACTGCCTCCATCTCTTCGACCTGAGCAATGGCCAGCTCTTNGTCACGCTTGTTCTGCATGATGAGGNGAC
+
5#9<<1GA3$E$>&+=)3)=0E;'EF)7#*9G63*+/<*84B<#G;:=,&0=7.A;(FD*3E7$BC48'"5)HA>FFC*"1
@r4617
CAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGA
+
'*C+(BA3/.6/A8)%E!,-.187!#-@)?.H1A-%.5:/+A1*9/96?3D%.&BHF'-?,A@=7*$#G%GE/#"1.B4,16!50$-50D9&
@r4618
CAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACG
+
5.F6H0*A*D=(,6,B,0"-39'=DF@=+.)GC(6(+"9&(/*EE
@r4619
CCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGC
+
9,:D.*/=8%"8=C)0B,%$!*2/E#2FB4.!0D9-)!27>,B3$,"E1'3EE1<H72G/!'6GC8CH4%#
@r4620
GAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCNAACAGCATTGCATATTGATGCT
+
=!*%7"E.G%%H724"D7,2CFA1":*!"&'/0A:#/%,1C%@0B>%1A&(>EAA18
@r4621
GGCAACATTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTT
+
F=#F=*2<)53$B-@-FH<4'$CC=E+;6:4D",$D)%199G106!!(;:08&B"=?*(@/A*8>H9:!'5*'CH>D.EA.0=CA3>:;"<'%.5=<
@r4622
GTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGC
+
(@.-#!*-+>!1;'H(@HA8!%#!;=")+1/B9>5B:C4/B1A!
@r4623
AAAANNNCNNTTCTTCAAGCTTGGCTGTATANTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTT
+
$#**%"''#$$*))"'+&"$"#+&&!("+%(+)$*"$+&')(!("%+!%"$!++)$)#*''!'#*%)($"(&"**)(+(+$!!%+*($'*!*%#*"'()*&%()##%)"$''))+#+*&)#*!+%(&#()(+)$$)(*%$"'&"*#!+'%")+'""$%"!#!'#*
@r4624
ACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACNACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTNNTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGNGN
+
*-9&$6"$@'.580%54;"%"2+"3G?//&HD2("@C?+#CEE!=.=$3:0=$$-7"F:?!5,AFC+/CF42?&4?C0.::+=(E&D-&A$-9!-$4&<;2%5/'H$E>5"<!H904@'0FD)'7C032C(4E8-:<G<'-;?'AF=G$?:*DC$>'?A!F15?"!D7:&@CE07(()!;*!&3#<C"@,8GCH5+D;AD,4<7<40)+
@r4625
CATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAAC
+
">7'4B8;+7765C-G=>%"<B0>,;A+#$:0%A8+1E<9@C'!C<$GF=)+'/6"0H')67+HG:.3,*&D;B<!>)":E+)ADB!F9CAH4-)#)7$":4EDG&6#0001$8E$EC.%4@@#D2'9.+4<%!AE+-?(8)9.)!>2;F;+!,(9?>/;C47'DH
@r4626
AGCACCGTCTCGGAGCCNGAGGATTCAAATCCCTCCGTCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGG
+
D8FF6!7$,21$'+1F!=B>H$H%C%G$83>:F4,'$G4#7+"+-4A25+F--5.'+%5$DF/EE1%-(&5F"F3-)H19=-*'$/;G@0/=:6B)B,?<56H)#8;/!0**6#<5@0(
@r4627
ACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACNATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGG
+
B5+'$4@;><;<)%'/H&3)H;@:1;43?:::D#5/D<?C'25%DBA2;@.:'*&:3H/5';F(2B$:"(5#8!$FFF8.!A$84>.%"CA'-H<!33*6&<-$+&BH
@r4628
CCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCNGAACACCTTGCCGATCAGCCAAACGTCTCTCCAGGCCACTGACTAGCGATAACTTTCCCCANAACGGAACAACTCTG
+
H,!(9$D)*D+#4DH%4-$C.&0C-D&7"H(>!1=%&(,0%F0=2!#'H%+7+F+D*?'F55($7H*$9.(/3,=2E%D1$<5/B8+-D3F72.!73;B&"102?<;=>8@DD6A31':*,=HHD5)#D
@r4629
AAACTNCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGG
+
@C#*;57H!19?1#!189=;.=EB":;0"-D&1.F,(%/H)3:)'5$C93B;:G($<0D",#'1&:)E)
@r4630
ANTGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGNTCATGCCCACACAAGTGGTTTAAGGATGAANA
+
"'+#$!&$(!(!%'&!$&)($%!#+&$("%(&&*+++('"+'#)"$("'&'%)&""%*%"%&"(*)!%$$'*$
@r4631
TGTTCCTGCCATCCANCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCNCTTCCGG
+
().8)+;&:6DC:E?!+B0,#E9A5<'E30+'A>>9C#74@57?,DA>'%A76A$%=(3=6-&C-A?8/?%=3@=1FE6BG6-7>E@'<057$&#>54393("8"06(&H3E,C1''C6A!&=(;%0
@r4632
TTCAGANGGGANCNAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCANCATCACGCNTCAGTGTCT
+
#$%*)($'%##)$!&#$+%"#)#'&+$"*%"%$!#&&*')"'#%%&"!)")#"%%+(%#"&#)+&#'#&")*+"#&)(%'*%(#'(&((**+&)(('*#%'+"
@r4633
TAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTAT
+
<4;!4!"<>#/=A!0"*=&(9*")/&7>B%),#$FD!<!&C,5D0.AA-,F41?/%:@$+)B
@r4634
CACCCANAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGTTGCTCATGCCCACACAAGTGGTTTAAAGATGAACGGTTCTCGCTNGAGTCAGTATGNAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAAC
+
E5=C@%2-/-G9GF9+@5@@C,C"A$G&(>C%/":*H=D.G>2@)>E,AGCGF:F%/;D?C'/35.'A'E(''C."CA6-53?%/2,&H,(0&*6,E<$9$H=,;EH(G*H;3,E&'7>=;;1.*C*&87D349-GE/BH(%$<87/':52<,!E!9;B==97)4(66-?$0,96;"8F12!06:E-3).:4?A$A/&,=-=GD7$.?,!-;(C9/!2G%G?41C8(=5GE<7*51*$9$$D/BE>'8<C!+7EC"+!:,H
@r4635
NGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTACTCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCA
+
"&5:=:<CD4$7$-*,2::E4"2'7>EG1$*'G)2<,#D)%/(&!87H/27=%:(/8<)C+(!>+(.?6GE(0DH#*<==<.+7*>"=D&%,$&G>-
@r4636
AANNCCNATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTAAATGCGAACTCCGGGACGCTCAGTAATGTGACGATNGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGC
+
#)$#)'!**+'!#%()$*+&!%$&!)%!#(&$+'+&%#*!*$))$"$()+$$$("*+!"++"*&!)')+"+#!)#"$&"!$"$#()#"'!!$*%#*++(*((#($+))!%$&%%+$$'*$&*%%&)%"*!)((!++(#(*###%'!(*#$''$&)'+%%*(%%&(%'(%!$#&('!!%(*#((*!'!&)$*%!%&"+(&'(%'%$$*'#"((*+%&*%(!%*(!*%%+(!$)$'%!+#%#!)+"")('(#))&*))*$#*('$$!'#%)(&!%$#!%"$$$&(+(%
@r4637
NTTACTGAGCGTCCCGGAGNTCGCATTCACACTGCCCCTGATATCC
+
!)+'&&+')!+%$'+))'+(!)())$*($"$(!**($(''+'&&(!
@r4638
ATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCT
+
8#*+A9(79'E+1E%)?="40).''!H!,5D4C7-D5/2((
@r4639
NTNNNCNGCCATTGTTCATTCCACGGACAAAAACAGAGAAATGAAACGACAGAGGCCAAAAAGCC
+
"*"!!"&!*+)$#!('"&)(&&*((!!!+*"&*'"&)#!#("&&$%!)***)'"&)(+'!$*#*(
@r4640
AGNAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGA
+
622E(FB&7FB&@%"F02?,G49%H%4-55:/#3@7!+2024(7<%G726H#=!.(A"C&:0:3G;0AB<#18@69>/
@r4641
AGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGGTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAA
+
FC5.4#BC=*#!.,(<&HC(<>7560A6->85(<,@=/D)D=561#9,/%???3)AC8=B9D4'H<G?H+G@&/AE919/A-F*?'$17FH*/A#76>,#-A94&1H!D2+5&F9BF3&:<B.<)2554FG5@$99)@80)20A5)7'&:'H<4-37%+72F<E.1@"F9B<E%8=2HCA=%D$>!>--=-.(?0"9>31//A9"CF6415%"7D"&>BBA:'HHF@!8+!$=(3<C9=0-
@r4642
GGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGC
+
B*?"*D.D1&BH9>:".+7A9$AG2#HE?-'+(9(200&3$)#E2:5C9#+(:;83>?@#FC<$&E9-"CB5"9/EA5:1/H+%5)/6C,<3)8H&H92?
@r4643
GTGACNTGGAAGAGTTTCTGCGGCAGTTAATCGNACAAGACCCGTTAGTAACTATCNACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGG
+
:0%82/=$4/"4CF,%83B-HG2=,14F;<H-86/@3EA4/B&>?35,;804!>82?"4FF#%-G"3?1D?3+*#1BB#92)*67"21<G=D$GB<"FFE2<*C(F&9#E27
@r4644
CGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGANAATCAACAGAGGAGGAGAAGAGTGACAGC
+
B8?F87CC>>.-11)1?=/F!C$&24%1/=1$H#&0>5>)1)D3#'C<C9'3$+$/3@9%23F6$9H&?&G
@r4645
NTGAATAAGGAGTCCTNAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACNTAACAGCACCACGGTGGTGGTGAACACGGTGGG
+
5!@&13AH=C>?'#6/4%>#0!.;7%/;0D66#D4-B'-%,*@H9?>+=!.&%-09DD<HB$1D5"1?)%F8($9?'B.51$20$2>AA+B@4("'-$$-#')3<F
@r4646
CCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGT
+
)>/14&A3/60<A51!HHEH?E85'=6"1/'D'*7?E*D)':4%/$(%('"8$1?$!!<1E(&D#@%!31#-?FD"%$1B6='B)'GA+2!?&:?>G+6-$6D1773/A
@r4647
ATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGGCGGCGCTGGCAGGGTCAAGACTCNTTCCACGGCGA
+
-<;:3%D5("1&F%C"=*G@?,+$,8C@$69%,"@EAD=&9?,@1C,6)/.B''$;;-#EB'76,*A';1@3(17>31)=A
@r4648
CGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCTCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCAC
+
=E,4=F&)(D@FFDG)EC6&?"%.?B"":#DC0##&0*39/8-;+"G:<$/=47441B1.D4&05D"*H+4F)5H/8-")<+&4:8=(-2B+(&!>G9D=&3(B%65.%%?14F'"B/<7)"8"4(=?@G?E)(@@"2E?=G'(92#$37*H93.F;1@#!;CF6*.C5+(1;=E85B1;#8*H>3%"1>"E0HAGFDF#/G*=/2/($+5
@r4649
TTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATANCAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAATGGAGAGCCATTTAACAGAGTTNTC
+
95,3&@+%=+4G$F0%'11*<7C;*='0<-:'*F-C(,)#>3.6.@9/"(A!:)FFB8D-68+BF@5:$1&7A/C8+;6,*25,.<,@F,8(@%G2)=D>6$2&(@;17)<#%$*'=FF>2D&1$/+38H9@*#>95=)<2,?20D$3<=/+'G7#)99C1/>B19)!$14&C*FF2(?2;A7<;:1.@!%D#F
@r4650
GGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATAC
+
HF5=)?3@7<9!;#DEE/0(>.*+<:5D<)!#3G*?6;C162'
@r4651
AATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACA
+
E,=G1!4H>62'C;A7?%;=>.!,):1"'<5;+#/G>-6<88%GH;=('*;,)$6)1>C:GE&/&#?G
@r4652
NNNGCACCATTCCGGCGGGTATAGGTTTTATTGATGGNCTCA
+
!""(+$&("!+%%*'(%$&%)''#((&#)((*#""%"&*"&+
@r4653
TGAACGTGTCGGCATGGATTCTGTCNACCCACAGGAACTGATCTCCANTCTTCGCCAGANGGCATTTAAGAGGTGATGCCAGCGATGCGCAGNTCATCGCATTACTGATC
+
+*""$$'$*(+%!''"*($&"$+)")*!'"*+*#'$+!)+""$)!!"(&+!"#%!'+"$(%#&#")%!%"$(!*($(*'#!$#*%*"+&*$+'*%"$'%&)!"#(%)+*(
@r4654
GACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCATTCGTGTATTTTGCATCGAGCGC
+
G2>.*/1D?&:&,>.C,?<D2$%2///B>B>=1AD4H1-9;3829G+!2<)CDH?024H2+)781GD8:;7GB"E(3.3/7BA++!C2
@r4655
GTATGAAATTACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATNTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAG
+
A5)5/)>.?";:?H9!,C:!:**B>%+(662-6<!(''#?-8(.3:A&&""8?2%53>?9($&<@7B=H5">;?@=;E2.)B48EF1@F@A?1A/3)&@F;B!"4/F#,(:?'=
@r4656
ACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGT
+
(<7//G%$>).&.:+?322$;:)A33>9H@E5C=F('G@98&>F21.
@r4657
CTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTAAGCGCTGGCGGCGCTGCGCATCAGTATTTCCCG
+
F7A:9?*C.E.="H8A2>-C;9>$FE<&90H<15F(987<1+C---!,G3F*!.6<4-EB0FCA!639F5A:*F0*96<<-@/>G6"'"*8;?:'F%+"$G-;4D./%3>80AF"DG;3,;+9G+4,
@r4658
GCTATATCTGCCACTCATTGTTGTGAGTGTGGCGNTCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGNTGTCGGACTTGTGCAAGTTGCCAGGAG
+
//C=,=@?=E<3!592"/F%>9@0!"5=<6,;4+%H&4;0,56$A;,A9>3-GE)F:;5@A&(GG:2*0A;>07)H),9<)!-2"7,F4C>;4;=#%B6
@r4659
TCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCA
+
32H9?<9#=!0@(!BH>-+3<CE(8!,*&7/%83D+:+1!80.;9?*)G;0*"59C0,B2"BG;+<"DB<<1*?/)>
@r4660
NANNNTNCANCGNNGNCNNTNCAGGNNNNAANNGNTNTTCATNANNAAANGNNTTCNATCNTTATTCGCNGNNNNNGNNNNNGTNNAANNGCACACNNNTNNTNGAAGNNGNNNANGCTNTAANTAGNGNNNANANANTNNCACANNNGNNNNTNCNNNGNANNNATAGNNANNTNTTGANTNNNCACNCNNTGNATNTCNGATTCNNNCCNACCNTNNTNGATNNTCANNNTNATGAAANNNNNCNNTGNNA
+
#$!!!""#$!$!#"##$##"$$##"##!!$!!""#$!"!$#""#!$!$""$!#"$$!"!$!!$"$$!#"$$""!!###$"#!"""$##"!"$#$$#$"!#"""!#"$"#!"!"$#$$$"!$$###$!!!"#""#$#$$$$""$#$"!!$$#"#$##$!"#""!"!!$$##$#"$$!##$#!$#$##"$#!####"#!!$#!"#$$!$"!$!!$$"$#!!"$$#"##"$###!!$"$!!"#""$#"$##$!$!$
@r4661
GATCATTTTCAGCTTTAGCNTCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCAATTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAA
+
%+(++++(+$#$&'((')$)#+#'#")(+$!$#*))*+#*&''++**')$)$#!"&#*!'#&)%#%)+')+%&))+&!*)%")##*'&'+!#"!$((!+)#'&%"%&(*"%!"%#!$!%(")&*"+!+$!$)**$"!'&"$'"&&'%*"+&#''+&"''"*)*(!'$
@r4662
TGACGTTCTGCAGTGTATGTAGTATTTTCGANAATGCGCTCGGCT
+
+%'$#)$+)%)(#+)#&#&)"%*$"$**(&(!"("'!$%)'(&+!
@r4663
CATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTTCGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTG
+
((B+/*&FA%@%>B"%89378:*-6E>:BF*1G990%1?+F9#7&"+->=%/2BD'H,C=;*G5B4H)7$;<)88410?D76-05F$$:G!?D:,E$8/G#CB>DH+)"E70=AF'F9+3*E2&3D0.<6>G-%F2255<-F4>)@'81#;A@(*104+8!7@=&ED.(C$EC..0*5:'9:%5&&E5%=5
@r4664
AGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGT
+
/F(2CH.>-/E&/)-6F0/'99HF1#?.*2.&!?CA%G>E+'-H?#7(@F)H)*%,.$4E9A!CB*=
@r4665
CCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGGGGATGCCGTTGACGNACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTG
+
H5?061>1%.C6<G9)'-"AH6%5/$83;?:7DF3""=>?<-50=-+/>1FG&B#:=%*5&7,FB(.)%B67:$+H9DC?#<79;21?"<7><@(C@0$"=*:E>E+)F+!7(9-3%6$DF)H1>/=3ECB@>C$((1G+8GF$<@%CCG0!82C"*%D#G5%$3H/?;*3",C8./E(2AA?<16-(6F!80D)*7&GD>)7.C5>C%C3#!04B(@?=#C/H'CG>.?1*@2+3?>--?*5(-
@r4666
TGCAATATGCTCACTGGCTACCTGGATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATNCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAATCAGGTAAAATTTTCCGGTAACNGAC
+
!';A#07?4F-H=7,/E#()!@4)@'6D:C:)89D2$27"3B@+(8@D,'>1./-8*<+<-1E$+#;1D7*1G!@,.-66$3'5@BH5.#-!+"*@G@/.C0<!E"-6809'%H(&4,;84F2<H8;!1ED:/3!:3C@'(7=B%=B/=5#@<''&H1515@8/
@r4667
AGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCA
+
8%G2--)BF*@1:<BE3=-,F.$!#A15$C:9'F&6,!#=4E:
@r4668
ATTNGGGGTAAGACATGAAAATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAA
+
$%&$+$&#+!#"'*%'$+)"((%%+**+%%'*#+'#(*"*#&)#'%)'*#($#'&!)$%""$("
@r4669
NCTCCAANGTNTTGNNCNGATAACTTGTGTGCAAATTNCATCAGAT
+
(!&%$''$)%$%(!&)*!#&$#%$+%*+(*'+&(&%$!$*#'&'+)
@r4670
ANCCTGATGTTGTAANTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTG
+
%&,!"E@?E$2&:-88B4A@>=14;%H#7;51#/G%E8.4$?3@H/6(%/H,278H=A"-',-'GC1,9,G!@F@."
@r4671
ATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATA
+
('C/GG&*.."*!E6"&>$,%H2!>6,56C@&(B$3H334/!EB6*"39,3&$G*B,"?*"29FH2,!8>@FB6?A;%"69G)-21CH+FH,GAGHBH!>%50H12HDDC8'>*A'?AB@!'FE&"9<
@r4672
ATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCCTNGTCGAAAATACTG
+
2+81!B:?F8AG5)(=:#AE!5-75.AE7>/C=B1/E*?'$(+F>3E5/C7>B8.,%6$5,-.0(=AA%G@0&:+7)BA78>
@r4673
GACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGANGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCACCGACCAGATCGCCTACCGGTTCAGCCATACCGGAC
+
?EB%.":&E!7-F6E9+18)68<'<HA$')>=>!:$.8./)@<=4$>&6:4G(2?:#!$H#/?'"9D&G%9#8:E=&-%&"G#!'G+>.*7>'9***H1F/68;1*D0-<7?204/-?C/28B8&B:"(949!.B.)/A#6@?AA0$GCC2406A:3C:EHC<*4,/5'B<G"5,3-=C:D2C*<)-.A:@"@
@r4674
AAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGCTGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGNTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAA
+
)=G=#,6$0GB4BD-)-/-1@E&2A<$*/(?F/0-75+-2.2+,E<B,4/%.5-<D*&$4/7<04*)4+/%>F6"7;"7(4;#G)?5-F26210)7#8ED'?37&F?#(=G-&2==9;,#=B'#EG,&GF51:EFE6@H57#7H3+.F&(0H;;25(!4C(<DG8/C02/"FB,&9'G)!>G99-&BG,'6$$E3-<D5!,EE:B<:4>='D#;!D:+81B";E:49$!-.</!;2&&+:HC;,2*924CC$+..'#"8+!=:6'$CE99H9!B"C!H&-"44$H<H<?7'!<"'#@(9F1C.#CB5@#/<.,91.!8C:.>'('4-G"+5A/'<*78,*%/.DA9
@r4675
TTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAAT
+
$9?!36+("-F%/667@/*-'+&*455CBG:.@3/7$+$D+7'2;$;/!-+!$28'>H4HC
@r4676
TATATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTA
+
""(G!11'"A+:<D',:'#A""/:6)4-E*>@!A'1?A@.AB#-";4':;F6/<=%0D>>-?H)>&0<5$8)H6:
@r4677
TGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCGGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAANGGCGGTGCCTGGTGCCGCCGCAATGACCATTAACCGCTTTGCTTCATCCGCGAT
+
B?H4+(B@3)9@@6B&*??<>B@&;"2$5>?"7+5D;G5E1=($9C9&H5,#(+?!@##3AF/)77E,G2=*6<<'0D%*71.A1C1)#9<E:E>..(&<B.C5,=E:C.=:G0<"C8971$C@0,4C728567"5%&D:14GBF4'5>37)*&11#,?D(C$82/D>6<H7A3A1(@:3(.:F;$$A!+)0$.F#2+D6;8%7/",-22,:!?E/717<.4-,593*BAD7@6=018C1:G92$!+.=90@B"@"$'A<-"(+.!G(#?!?9<F4;G&.G75:7>;&7:"G'@D&+)288,8C*85)EGFF5#8;G2H#%?7:==7=4:.:;.3EDH$F,"E*%:@9=)2!26D#
@r4678
NCCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTNCNGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGT
+
%,,68&1%$9H4=!<?F*(0:6F(9*1516!30B,F;EF09,,(-@5H:6<0?5/?F39@(%?"$$&(+/<<1;#:445"*+7-*69;"D3*(>,=),04G'3+4!#-B.16*@*?9;7!:+;DBF27B;-'0D5,#-E<5?%@4A!@<*@G22B%+:92,'=6@63'#<DG$+6E;+.819<6,7F9)A*A$E/1'?64:8""<2!4A/9002')0&:
@r4679
GCGGCAAAAACNTCCGAGACGAATGCCAGGTCATCTGAAACAGCAG
+
@%/E@6'A+3/#H+H5@+':58:%55('@F'C&CB*$0H4*+'@9!
@r4680
GGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCNCGTCAGGAATAACTGA
+
-@+F-+=/.H3,@4(#C/!*F<!2:<CD8(*&;%FDF5)B086=E$:2ADA;FDG.F>:.!@:/&ED8&37:-790H4.15/8>0G!3F6
@r4681
NTAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCC
+
%!*#+"'$%!!%*+")+%)&())$#%()&'"$*%!'$!$%"($+#!)'$)#'+*%"'"*'
@r4682
GGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGNAAGGTAGGCG
+
'14&8<@1%7.0.*C)/H60&'G6.+<+=B+@>F;0>F#C9-E()'%=)>"/
@r4683
CCAGTACCGTGGCCTCCTCACGGGGGAAAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTC
+
E9&'CB6&E08>*2"!B0;E49H?+3,E:-=G@2*E+@%&.(B=8:'#4C(H<#G3$54B:*84=
@r4684
TTTTAANCGCTAGATGAAGAGCAAGCGCATGGAGCGACAANATGAATAAAGANCAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATNTGCTTAATAGCACCATTNCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGNATTATTCCCTGGTGGTTGACTGATCACCATANCTGCTAATTATTCAAACTGTTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCCCTGTCAGGAAAGT
+
:0G9=DA7'H0)3GB>D5!(548$5:".F526-"9)&;C?7@6C!B>,?+/#+<=C@D%7.9$%>7?D%G3;<97-+G$(G3@5@'*6E=H0D;+<,,'9**<1*=C,5&,C!G2%("-?A*"7A.G=45$8/6FD+E()"6#F0GGA-7H2C%)E-E'+F*@<6HA0/@-8..C61*>5-F8<72&/G7@%&5-?'7B6CDD*E&<#+H98.4!$:#*4;3&DB8.!=8F7H7>9.=&&@G@G.%'<E1F&1C!5/30./.59=D,7B>C*6(.!GB)19!=<4#0;:6>547.:7C-90?557E%#-@BE=15,?"?0C0$1
@r4685
ATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGANCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGT
+
H&2%>6H</&,A<'A=)0HA<&</((>@'2%%/#;19@&<7BC2@:+G!(:HG()A).7/G4@5>F<C:+9&=(=6;"8<49*$96371"0%9-G%+14GA
@r4686
CCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGG
+
*0D&(@H"<.%(%/;*:0)#B-*7A2;>)B',B"/''10()$.9/1=E80C8!A:.E!6D8>*G'AB<5:=753+"';;)EE5DG7E@A$7<CGE#.H$G0'BD;A%#.'B1
@r4687
NNTNTCAGCCNNNNGNGCNNTNNNGNCGNNATCNTGNTCAANGATACAANNNNTNTAANNNCTNNNATNANNCCTNAANGCGTNNNNNGCNTTNNTTACCNNNAGCNTNGNNATNCNTCNTCNCTGNANCTNGNCCNNNCATCNTGNANNNNTTNTCAGNNTNNANNCNNANACNTNCNANTNGGNNANTCNCTNNTTGNANTCANGTTGNGTNGNCCTGTTNCNNANGTC
+
"##$$$#"""$$#!!!"#"##!"""""!#"#!!"!!$$"$"!"$$"$$$!"!"$!$##!"!$#"!"""##!!##"#!$!#!####$!!$##$#"!#$!!#!!!#"!$!!#""$!#$!!#$$#!##!!##"$#"!"!"####!"#$""!!"$!"""#$"$#"$#$$"!"!!#!!#"$!"$#!!#!$#"$"!$"$!$"$!"""$""$#"$$#"$#"$!"!$!"#""!!!#""$
@r4688
ACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAG
+
;H?EH5D228406',(:>+2CD6:>!3+?0H65>$<>:?7)C#"1$:*,GB.@=7"@!3#=BD@?:>A7@
@r4689
CATCAATGCATTAAATGCTCATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGT
+
%4'!BBC&?B8!;:/!)16-B6F1$7%@5592C$FF4A-.5?G0>G&3.*1<"$G0=3C1G$&,G@
@r4690
ACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTG
+
CG*5A<.=":9%#'1D/-"@*B+(F/:86-2F&@"4=C-'2-<,G70BBEF4?-,-;'-$A((&1."8:<()
@r4691
GTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAATCCCCGCTCCGGAAAGAAGTGG
+
:&5C&&H-D59-%96/@#%8#D>"G:4;9G%&*-A.G'/3>H.$?;2>*%:7!!'F4*&F@!AE3<'<D?><H)'!5#3<H2
@r4692
TTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGA
+
%9;C#7>5'**B-%D76,@B014%<1#E;/,:C69%6&8!*#$1?;%3!4F'/(0<37>.55#!A8"-*))@3.B=</.5E%C*C/>.1!-).126F.44.*D);(>.BBB.<*3'!":#$70-9)B)<-;9:/?2.?%$):0(.F/HFH<*,068!F-E74C7$,3'7;2-:E6GF6;7&.5;*=F1&75@">"#5352+>"C/9*B%9G7/49>10A&'"GB..G>/0?C@:$5)H$%6<$<EF%39%5$;>49F)9"H.5G@>&,!6%<#=,.0%@@E<-;:B)&6/-(C,?))G&(/-EA!#*+%*(;D!E&0E."@!:'(#&CBE95A@/1-2%87-D97A7:>9<>=HH5<G:3D;>
@r4693
CGCCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAA
+
&($+(!%%')('(+"##%!*&()$*"'!)"!$))&#'+%)*+)!$'!+')&!+$"%""#)*%$&##%+%&$&!+#!!&*!%!)'#"'"&)"*)
@r4694
TATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGNGGATCCATTTCTATACTCATCAAACTGTA
+
0%%#?:!4@C)'.9C:>+C5$"FFC8?>0>.ED&6:)H++0523/D";/(99;@#9?"BG2$4?C&03.4%2'!9%8")-DDDCDF
@r4695
TGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTNGTCGATTNAAGTCAACCTTTACCGCTGATTCGTGGAACAGA
+
6-<9.+8A*A:70)/,'8E6;90$$<*$/#)01>"/0;F!/)E?$G/;E((&0BC&,8F16@4+??6<9>A?8;@+(3**'H%H3!?<)'*@:%<4=.FD>.)CF-&'H<%#@@;'@&C8>@-#&E2@$=::66G0%>HF2/**2-)66FF2-
@r4696
TAAAGCACCTCATTACCCTTGCCNCCGCCTCGCAGAACGGNCATTCCCTGTNCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCAAGCTGCTTTTTGTTGACTTCCATTGTTNATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTANGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGNTCGCCGCCCNTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGAT
+
EE@(G=@611!D"?&G)9"GH;+59-A0#.=+5-2>"-$@,!9?,G!!?<CE7A3)G#!(,B$!/1&1@B3G;=(-H%+?!'-(8E$3(15!F289)/*,B&H6';CH),%.<>(A=&F*CG,@C0F0(43FD+2+7G586A>5!&".*?6,&%?)B@B%CA0D8+<@$$GC%C:'(H:;D0"?(&"@B1,8;/4*9&12#.#C*392,.CG*G#9)81<-*D*G$;%'E'"8;)?3CG;(.?/7G!@B,89>2:>4-,)B!BD-D@7F&7F'2#(9'C*=FE84"?33D"6>93B8=!,5#!6&BD,4>FE?F63<!G#H!ABG:,/29?EF78FD2BH6!B3:&396#:F19?62-5F"2@FE!57"&)>5,1E<;6-7D??9.2'#5D*C:B<*3C.32C@97!!(
@r4697
TGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATANTGAGACATTCNGTGA
+
3?:98;DGA<'1(5#1HH?;=?**D*DD8'2E5++*+73&%>'EH&$9/8#3F7)E9G>%'&1+G;:>A>4EE/H$#-E-.4DE$1;2)!+2F$%7#(9600%#*F'!*7-*/2@G).'41:36&?<*F
@r4698
AGTCGGCGTCACAGGTTGCCCGNGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCNGAAAAGGGCCACGGTCAAAAAT
+
<."E=,G6?5C6C?&65>/",9*8;/;&7B.D7F-A?$>29,3>G=@<)>3#HB#(&&#'B';9&?'=C0/'-F/B#-*#$G'70'#1&
@r4699
NNNNCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCTGTAAAGGTTGACTTAAATCGACCAGNAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGA
+
"*)&&''(+!"*&%#&!(&"#*((*%++$+#)#"%(("("+%*"$(*$(%(''$!'$**"*%!!')$('%(!'%#++$"#++*()*##()%)$+!(!#*!((%("+%'"%#"+*!')')'#$!+#('%"!!"($!!*!$$+&&+##
@r4700
NAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCG
+
!B18%:>HD)H<(+,-8?2(A.3/8BD6A,D;@37*)1/=.BF+!.3
@r4701
CCCTGTAGNAGTAATATCCATTGTTTCTTATATAAAGGNTAGGGGGTAAATCCCGG
+
1C#>1C+9B80H0@7:6+@2.2B>AC*:260E=!'"!@!7!7:(0E.89)F$F#@(
@r4702
ANTANANTGCATCAGCTCTCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCG
+
)"*!!!!*($$!)('(%&#+!)(++$+)**)'%+''*#!($*(#!'&+*)'*'
@r4703
ACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCNACCGGCCATTTTTNAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTG
+
,'9<)?;7)(>#=4(")1*($*/+87"<@8<@0:72!:*E>&/GG*B!DHB%5&F!!5F41<F:F7$A$$=?"09>C%;9#8D)9C=(=!*B2*-H7;5!&*%(E.>5GH3+*-2;15#097+#1:EA>:008$9>5>
@r4704
GTGTTATTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTNTTTGCATTCACCGCA
+
*+!!%!%*'%"&!&"#+'+)&#)$#%*+%)'%((&))!()#%!&#*'!%'!)&(+#+*##(+(+'"(*%)$+"")++'*$$'
@r4705
AACCGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGT
+
9F1>&G8&A)='A?G?'*%;'0+%>?GF267!1?7B7''2((AHF736!=!F2B&(G:<14=)>
@r4706
TGTGGGGATCCTCAACTGGGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCCGCACCACAGAGTGCACAGGCGCGCTGTGACACTGCGCTGGATCGTCTGATGC
+
(&!++"+"!$*#)+"&($'!(&&*$#(%"""%!*!"%%#"%"+"#(#*'%(&()*!&%'%)"'")%+*)$($%'''+++"*##%(%(%#&*%%+($+&!))#'))%!+&*'*#$$&+%&)$*(!+!$)!'!($!!'"!%#&'#$&+!$%+")()")%(
@r4707
NTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGG
+
/@8G08:';0D+/.##B2;D77>,E;/-(C"(92;"1F=20%
@r4708
NNNTTNNCGGNNCGNTGCCACCNTNANNNCNNNNATNTNTNCNNNATNNNNNNCCATNNCNNGNNTGTAGGNTNTNCANCCANATTTTGCCGATTAGCNNG
+
""$"$##$#""!$!##!"##"$!$!"!"#"$"$"$#$#####!#!$"!!""#"#"$"!!!#"##$$!!"$!"#$#$#"""$"#""$#"##!!""!!#!#"#
@r4709
TGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGA
+
3?319#3C>G'%C.8<&.F3B60&D,G>C?7-E,/04/AE
@r4710
TGAGGCTCAGAGCNGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGC
+
5;<CG#AB-08:%!&81'G5D=1&96'*?;FH-."2(5A;?9#9<1<2@B1*F#/G#(!?0.<-@F
@r4711
GAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTCGGCTTTTTTGTGGGATGAATAAGGAGTCCTGAAAGACNGCACAGGAAATNCGGTACAGAACTNCACCATTCAGCTGAAAGCNAG
+
#D->?@&8DC*$2#3)4'4:/D'*<41-9C?;9D(B.7#$)G85HB@5/F"@G)%F<$0%H6::"67=3D:!++5CE*+8B=C7<':!?@.-4?':2FD51C?1,G:.1/$HC#60/F"#2EB?4-:5CGA;@'.A.?
@r4712
CNTNTGNATNCNAAAGCACATNCNNNNAAGTNANGGCNCNNNGNNNGNCNTANNN
+
$"#!$$$#$!"""!##!$!$!""#!$!#$##"!"!$!##"!!"$$"#$#!"!#!"
@r4713
TCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATT
+
;8:D@1F48@9-%%$5*("45&@-3<=3$D4/;,+'9%28.0FE69+=A9846-%4(
@r4714
AAATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCA
+
##3((904+F57'D%G44'<C$;&7";!4'F9H$F*94#=?F/*
@r4715
CCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCC
+
'FB@>D'42#D>1<,H-1=:D/"+(A"-D#>=+C>:-#+!'<AE".E!@H!?"F<&2F7F
@r4716
CTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCG
+
HB$2*D5G?)6,%93#=+G@A/9D;E=E=$+;>8<+6'1(=/-4A1<!.;C<:)'!/<<=2.!>1'3'?F
@r4717
GTCAGCTTACATGNCCCAGGTGCAGTACAGCGTGTGGNTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGNAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGA
+
))++$%)%##"+(()*)*"!&'*(%("&)+!(!+(*"%'&&%()$#$++&$)+%*'%)"&&$*+&##"!!&+'!%+$(+$'!#+)#&)+%&)!$%"('&()%"'%%($(((*$#!#'%!)*+"
@r4718
CGAAATGTTGATTTCCTGAAACGGGATATCATCAAAGCNATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTGGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAG
+
3F6$<;@30AH;"@78H5?"AD28$G3()63614B/=4%G*)8G64-*,F+9:=1%"A#:H$>=!41*(?%/32D)G6<34&C"0'EB+-2/9EE/@*-FA@:G"<@6*79-6G6H.A#>#'5$:$--CE+*,!(F>'>%E7.G"'!+C2)9)?#3-13A02@
@r4719
NGACGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTNTATTCTGTT
+
!*&):B)1"@%FG>/<,90@)H1C*2)$A#2)38%##H6@#0A7!*CE#2*:&2@/6;1D*%F'#48-/6F*!$5A)#;?72D
@r4720
GTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGA
+
)@0,#@)0#?3!;'@?3=81.BG#:4:=<@9<=;'.$$>HFE#/5'+!>#??0-:)"*=$)'
@r4721
AATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAANATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGG
+
%4A#1<E0?>/A4B3A(/##)0<"8299+0?'DE:=;F!)>0&3=(?$.?/G)$G6+,;92#1<,@,=%#42)2&<()&#2@!.=H>%)"#>'2))+8*@/4EFC:H<?>A!AE&%6,5B':+D>G343C,4C!"1868FD!.94C.&C*;$&A#C@$%&%-B810:9>$>(C/=&'&=7@##DFFC-B(:<>:+D)0?'5#5(@85-/2$1<0@,4+D4?,&51F@+-D,/A#!?G,D2+D6'-G
@r4722
CTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAAGTCTCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTNGTGTNGCAAAGCTTGAAGGAAATACTAAGGCAAANGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGG
+
?F;F.D$EF&A6?>HH,<</9D2F+2!2(29"?A*6+:"C>H0$6>E5,5A1%9)-'="4<B-B-<C681<B2&?,%FG&72&E5983#AH=4,A!D2H+'"/05/=:'6H=81+>D')/?3FG&"2F/!2<!F=+&?;>HA.50@??50>)90#DB#A34>@9#3?9=??4:A<,C!@E62(92"(=%EB9F9/+-9274B'%,-$,>(B>D@@16<>".50=2#C2(0&'@)99%<2#>4,B,C+HC-24D?.3'3@A-9
@r4723
AATGCAGGGTGAGATTGTGNCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTTATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTG
+
>G&"B=0.=A2@:31+6)"8'G5@A3)&"$E6F3,$=;%>HD(G+30,B4!A-"6&E27=&*;F4$5#4!C%9GGB%@)9%*:D!:)D6:70F'FA;(02C@@9C(+7&A>-($.G#5*84@"++*%6,&5&GG>;'A8*.@)89";&=-03?3D2@#$%)0H*(.2D""
@r4724
TTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAANGGGAAAGCTCANTAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTNATAANCATCACCTGCAGGTNGGCTCCACNTATTTGTATATTCATAAATTCGATGGAAAAACTTTTNNCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGANATTAAGAACAGCCTCGNAGATGACGAATCATTGGGATTCCCATCTNTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGNCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTT
+
?@>=C$&.)A4>;!;0./98)/6DE-056FH/=;9=C>%B)6#H6.)5?*B.0&F*=$<>'),?+F44H=*>+B4;('=;D(,H:918C)F$9+4?14:HG617,E2+.6/3""322G3%70@(GF:0162GF&1(@*'.)/(08"*;@8:9!F'39"F&/0"?@4.&$&8EC:7#(@$53$F5?9A.9,)5'911)3>B;8;G@F?D40D@><!52D;1@97#,,#069*<:37$>'C&#(<-.>'HDDH0*%81B8C<?FBG8"),D)80B&E;!@#@GH3(4$H=18@A<D060!=G$$2>205C+>);0"%9CE8$.-=<20#/1@'E:#H%39<447336"F&<D
@r4725
TACGTCTGCATGTGCTATCTGCGCCCNTATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCGTAAA
+
E,:A"C./0A>9<3*G;':+:@)-5EC5H:11=;B3:H9%E=5+F!*6,/F7!(3/?82&-F90%3F,+4B.*$0H#,?61*+C!>3.3:'.D&/;6C=3@,&$7D:)#AD*>'6#"')#>*';AB-A(
@r4726
GCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGC
+
<8E'!-7AA76$#@61D&9A*HC1"6!64EG7C/!18%(1F&,@)/#5A8EA"%9C$/2/343>7<C+HF/G1H)9B+H.&?1605ADBA<572EA(058EBF1:3@9#A/)F,82D+7=."*CH30<2-F2"(B<C"#1%"@<41<&G;5+3/4#-F6&(+0/#-8DAFFH*?"$1G!658!(G>
@r4727
ATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGA
+
>G&;EE>G1GF"G7'5=>;<>E3H1?!B;EF@,E:/3+14'15F3,++)7;/,8D#0H5&5
@r4728
TTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCT
+
6,)1)>=+6H.F4A<C-;2,EDG?=H&16=%-1#*0E))96=.
@r4729
GTNCGNCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGATGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAAC
+
'&!)*#+%#$(#))))))+()$)')%!!'"'#!+'"#"*&!$+*)$%#$"'$'&'#++***!%$+$#%*+%!(!&#!&#&'!*#*'&+"(*(!')+##$"&$&&"&"")!($"!*"+%
@r4730
AGNNNTNNNTGCCACCCACTACGACCTGCATAACCAGTAAGCAGA
+
%#(""##*!'+'""*)!%#!*$)((*(#++!+$%$%&$'!+)$$)
@r4731
GGANAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATANCTA
+
89%#?>G=37H,(@#<%>,3*4.5=1$8F5&/=@B750'G>8?=:B:C9,/;7?3<;,H3AEDH:&7AGE8
@r4732
NTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAG
+
$,8?$.@?;"F?A@9A<E,@<="+E,G*$,1E7GD-4-:=E5@!'9*/849>&=7D<!>CG+D)9F7$CHF395?!A&
@r4733
NGATCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGANATATTTGGGTAGT
+
$(#(+%()!*)&$&*(*+$(("$#$$#$+!)*#+'%+*&$)%)$+"#)+'("*$&!*+%!&)!%'%!&(&!!!$)$&$(
@r4734
NCNNGGTGNCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGC
+
*%!!(!(%")+'$"*%"$!)*%*')+(%('!!#""'$##$%$%%$("+!!"')()"*"#$%+
@r4735
GCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGA
+
4-68+44*261/>C:'3F?>/>"HF:%/&>A?(D=>H-#-4"$47?5C3F02+"9&.?;<H(E
@r4736
ATCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATNCNCTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCNCCACGGGAACGGATAACCTCACCGG
+
&903$BC?(6D5$GD9$>B78$!>F.<GA-#H;0*E%4DF;@2"<?-91E049&<H=(/64@0?;8GDGB35+1&(6A#<'G/25F+>41A"<7A!$B0;58%F%9<*43!#$C!!/:98H>-"DA>+=8@E:C
@r4737
GCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTCTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGC
+
,HH11'!0,-4G2-;;"*-2&-=>G;&<!D+.C7'(=1"G3;1-*-8"<=$7983-7A;&>.&GH=A4A#FB#7?B?$!85G0D.&(A),%<"8-;5
@r4738
CCGTTATCCGTATCCTAAGCCGTCTNCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTAC
+
+"!)*"*"('%$+%%"'")%#$#%)#%')(%&%""+"$%&++&&&$"$&!$)#&"(*''+)%
@r4739
TAAAAATGAGTCGGTGTGAATCCCNTCAGCGTTACCGTTTCGCGGTGCTTCTTCA
+
"(%%''("'%$+(($*$%*($&%'!"*!*#'#(#%(*))#+(&$)(&")*!($!#
@r4740
CCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCTCCGACCAGACTCTGCATATCTTCCGCCATGCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTG
+
4*>='><'HC9?E5C(7H.HE<-!4?!FA.!52A'3$<("5"B6&H4+(A8"--<:(6D82!%'2*H/GB"5G<;D)C@!6>!'A="6'8H3=&%7CG999)&*9:9(7GH"D-"@A4H8#HA3&@;;-7B=D@<EF(.?4*A:"F+
@r4741
ATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTT
+
+"*:9/H%6;38,,=(+1B2!0D.C/($<;/DF:B'41'3+*'<!,$D)
@r4742
ATAATCAACGTAAGGCGTTNCTCNATATGCTGGCGTGGTCGGAGGGAACTGA
+
)D>9AC/B8&B(*?8EE3<D3$H,C"C9A22*C(,((A=F19"$$,50B/<1
@r4743
GGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCA
+
D=/24):A3+7@@"/11#)841">*$-=C?9@(B=1$%A$H/4,&8%8+(179:,>-/;B8:(>=27!E7&A?-=95D4%07$=;"
@r4744
TGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCG
+
626)#B+=.?8-#1)7(EE8?;C0:?.0!9A&$+6$"E**3"3>B4H'=$97?B'%FF8*1>!;@20E@*H6>.5&C+2-9.CH#1(:#?:.)CD8?
@r4745
CTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGANGNGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGNTGCGCGCCATGCCC
+
+)8;".6.#1<0'(+97A>0?>!(@29A*4$H"(<11#3-0$1<7G!@#6(2;4,@D3"9$A#2#/+#<?D=#:577&A3G&"?".*?A,10<%#""&@C2DD..%EG;%6,>=4!'.'@&F;3'H(G021,0F)157'6>2B+##848*(D5?8*.#!;D>!F7E;?&?,'-5
@r4746
GTCNCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAG
+
()'"#+!))(!%"*"'"$*!)#&&$!)++&"+%)+)''+#+('%)''&&*))')&!$)"'+*%%*#")!")&*'#$+&'%#)#$!+)%"
@r4747
TTNGNNNGTTCCCTANNNGCNCAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCNTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGNCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAATNTTCCGNCCCAG
+
(%!*%"!$%('%#%'$&!+&&$#('*+"*$&*&(('"&(!)!*+&)'"(*)"'!'(%'$$%&##&#!#%+*)!)%"(%*(!$&%##)#+(##$+%&(%'!$*++"%%!&)$$"')#)&)(%#)&#''(%"*#$$&'!#"!*%$!$)(+))*$!('&*$&"#'"*$$'!&!#")%(%)++"#+'+&##*)#!!)'%)$%'"&!'+""'+%&$+#%++)%+)'%*%+'#%!")$"#")*('$&)%%"(")'')'')*#%#)&&"&&(&((#%!#%*$&&++*"$%(*&+(
@r4748
CATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACC
+
,8)>0?G35'H*$,$G718>:4,<%9*D27!:#2$3!@HD?&'"BAD9<
@r4749
TGTTGAGTTAAGAACGAGTATCATAGCCTTGCTNAAATTGGAATCAGG
+
5&F"D4)1C0E+"C)C!6C=6&("971"5%:@+72H:@"H4H?FAE+8
@r4750
CAGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTNTGCT
+
)"/2&)*3G%D7=HD")=3,%10&,10,",41*5#4*/<#2981@(#81#-+'<EH!D$":<;4CC-=/B:;A&0*#HEA&
@r4751
GAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCG
+
9A,5%94;1=B-B0E%=')AC-6&-!:2=EE%6$12,D&D6E53++("'21'&*B.91=C'G45"%5760G5#+C0
@r4752
TAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTNTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGNT
+
.-2B0@6;)=9#+78?G5H71%1#=8*D4&(3C"6(H::H5<<655!2%8E&(>',>359/7)&!-A$HF?C&C'#1)B+0"E&088-H6"DEH*G:23E$G6;'5/D,1;.C#1#*GD86C</F?<
@r4753
TCTGAGTCATGCGAAATATTNGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCT
+
B.#9DE0DF!7*"DG#=0>)-7+4'98GG<BED8=3(4#"2#BAED$4(+G/!<-@8(++9(D!D74>C#+0H:>*<2)C5E1B>*<?40;0)2#5<0)14,6C&0D4;%+(-2B3A$/D/"+3D./)('#"&35)@5:#!B
@r4754
AGGTTCGTGCTCATCTTTCCTGCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGGTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTC
+
;,C6:;>9F?!&=FC'0(@'$?4085();G;/=GA67)B:6*G!,D-EA0B9$/.E+B;+3HE)//==;9"-'#H+@,&*!F&/1D=6>FA-0"F,A>%G:G9!A5!=CH?()7-4@C!7<09G+C$58?DE)1<''-6-&6(/,=9:,):)2<)H103@)
@r4755
TTAAAGCAATTTATGAAAAAAAGAAAAATGANCTTGGCTTATCCCAGGAATCTGTC
+
$2:!>7$+H&?1=#D6?4;A$BG&?);D#?!D:+02C!->9>D/<*4D7<,>&/7,
@r4756
ATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCAT
+
./</**94"C/"=>D*H>:A!DA;%34&E"DH+6?HF6@1#;9CE@*B+);4"3=17*)9+##,)(3E+
@r4757
TAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCAT
+
(++$($*'))'"$)$)!+#"%'(()*%)#&"(&($%)*)("+%"$*'
@r4758
NCAGNANNTTNCCNCNNGCAACCANGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACA
+
$***!"!$"(%$'$#!%(*&+$&$+#!"'!&&&'''"(*!!!%)**('#%#&"$&+$#%**'!))&!(&#+%%+"!"%"#%%(!)&$#"""%"$!!'+"$!"(*"+%+#'$!%&*%"%(
@r4759
CGGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTT
+
&+**()+!$%)!&'!+(&*#&$&%#+#$"+('"!*(*!+$!'%*#)
@r4760
CACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAG
+
>'70H?7<D<%BDHHF9@,E?.?A6+H4*B<E3!F7++,86"3(>A'.GDB/#4A)4*.?!F%6'6:C1-H6+,@'E+23ED:;1.&>%=".3%0>.6%)H5<>0/:-C)..23-/.'67:DB-)
@r4761
TGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACNGCGTGAAGCGGCAGAGCAGGCAATGCAT
+
F.5>$(5.,;D4943?G)A1F$<040%27.8+)($??5<*D4"E4H&>9<85B07FA.+!H)!F59H#6718:HA2F=>=!-)"4$1>@).G=1D.5*
@r4762
GTTTCACATNGATGATTTCAGTGTATGACGACCAGAGCGATTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGGGC
+
98'>8.:?,286,4F@/+@A5*)7!AG>&8.?(+%)-59?66<%4:4%D!D4)34.G&@+?*'>+5.:($G1$$H6B<D"@E?,>)
@r4763
TGAAAGCGNCCTTAACNCCTCNTTACTTAGAGGGGTAACTCTTTCAGAAATTGATGGACAGTTCGCNCGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTCAACTATACCTTTCGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGNTTTTATCGGGCGGAATGNGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGT
+
*+%(%#$)**#)+)$*+(*!*%#!&#!#!)(++))#$)&'!)++%#)&#&+"#$&)$%%($%&"!"$&#!(!*"()!)%'()*+#'''$*'(%)!$#("+&*+*#$&"!"$''("!'+("*)(!)!$*+%!*&&+")&+")%)+#)&+#)%#(&(&"$&#)(++'+($+%$)"#"%%&'#('%$#$*"%%&$))%$*&&'*(#"+*$+"&%((")!$(%+&$*&()*#'%+)$*("$()%!$#'"()'!&%#"**'
@r4764
GTGGGGGACAGCAGAAGACCTGACCGCCGCANAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGG
+
A5>H)8&/-";DG/7B"(;AH*B4$3"AA"*E.A-5,+C50-GG*16:G.4@B2",/A/:!*$/,/$B-1/"=;3F&!<>:2>=%&;7,H0B+'
@r4765
TTANNTAAANCTTTCGTGNTGACGNTNAANTCNATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTNTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATG
+
)(%"&(($'"*)(&#$"'")!'()$$!%'!%$%+$+'&!%&!"!*&%%$'*''#+)!%$'")))*&%&"*&%%)$$$(!!"(*$!+")"#&+#"###++%!+(!+#%%#+!+&')$$+'&'%!$(*$#+')%"*"*
@r4766
TATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGT
+
%?0+!3@<B!*)/+C!(91#(A9@1>A&5&*%,E@82&E<)*)4.:5##-**%%83)5$3+*9&"?<4&;2B?$
@r4767
AAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTG
+
?"8D>H!'$>0-1.'.GG>"B/;<F4C/$;$;?69@3BDE,D8))51@AH1AG'2%*%!<%1+.9G
@r4768
AATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGNAGTCACTATGAATCAACTACATAGATGGTATTAGTGACCTGTAACAGAGCATTAG
+
.12;=7.5&AE3#9*:8'2>9'4;E%$B!*F;A3""9%4(D39H$?*C720%.;//F0-;E;,A;#D'B??(H=5.='.%?*G?/7<=)6A5@84H*$#%)4;=%#&+0!,?=GB872%)#8"?A'#2&?58==A-BD3<1?&!:=H74E@;"6AE%;!3@%#<779<"(1=?.-G0FE?GF1H'0%1)?")-A7%G*"9:$2)!86#-"&C.2<>9);D!/D(F9++5$3DF=>#;A(F
@r4769
CACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCT
+
,*%<+/109FG9,$FB7#==!;?D%850C=41E#13&H0)>5/<?.6H,8<-E82)*13&G);829;5<1*DA>9=!?23;,!BA*&&$2F:#72>7*1C(F3
@r4770
AGAGCGATTTATCTTCTGAACCAGNCTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCCACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCT
+
>4H,?7!F".EGB!&9"'&:8!1:G<+<'E)B4$=?188##!06F(G<H?D!863B1.;0;8.*F/&(A'CB;:9>G+B.(;A,4G&2+DC2/EC=%0B;'#!H;F7$!#5%G/2'54-?D!3#1.D>81B84;62'/(4#+$F=7=?H>6>8066&+#7=9>H+?H=1>:'0E#<:358%0FA%>"&147F3)4(7;A$#+
@r4771
GATGGTCAACNAGNGTCAGGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGNGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATAC
+
'"&(""%*"!(()#('*'"*++($#+&"!))!$(%"%"$(+%)+")!'+!")'$%(#+"&!)&"'*"'%*(#'*!'"'("'!%)*((+)(*#$'''"++!*&('&!+*(&!$#!')"##&+#"
@r4772
TCTCAGAATGGTGCATCCCTCAAACGAGGGAAAATCCCCTAAAACGACGTTTAGGGATAANACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCNGCCAGAAAACGACCTTTCTGTGGTGAA
+
FHG$"A'0%7;!/&-D@;E0,%7@407$<2)3('>(&045#+BD>5-&,+@DE*H!?98$"/>(H:,#7-#8H1*'A9*5,@B-@?07041E4!'979!):E%/46;=*35@D3!F,82C=05*=#96CE0;&>","6?#,F:<0&D"$""/'D/>"7?E<'C:;<+8'2#2/7#$%;$;9A$>"06E'.&)8!F5H$E+):%2
@r4773
ATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGNCGACTTCCGTGTCTGACCTGAAAAAATA
+
63;)6*1=248.E(-%40FGC7BH>>.:(.6B'1:@D=;5C<$H<2&,/DA)5>C;8G,'(&?*;)2'H;0DAEB?.2%*F-9,H@C08)B$%G*;)9%6'.'<=20.4;G585HB80$98/:/4+$;5(!+083&?B
@r4774
ANNNAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCA
+
(!#$+(!$*&$'*''#+%!+"$!%&&*&!&)'$+%$$&!++**
@r4775
CTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACNGGCATCCTTCCACTCTTTC
+
.8(H&E3':?*2AE-79+=-"'(.05'7G="41$7?7GB?4(#$).+=H!?*B-?+.58A1
@r4776
GGTTTTGTTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCG
+
066!!B#H7*B%+G9+@"4B0@F'+408<4=3!$C/5#C47''$=7-'.%;.4FH/FEC'A&0?!$44$8"B
@r4777
CTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATAC
+
'7)/F(>0$'*<27CF2E@A/73,C5!(6-?&.%)1A3)+>C!,D?!*).'?:*2A>D75$"%2E):C/H$/7+5G7H>5*
@r4778
CCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTNGCACCGAAAGCCAGAACTCCCCGTATACANACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATG
+
)++#*"#+*#"&!%$&*%*'%*'#!"'!"&#&""+$"%*$+%#(#&!*"!$+!*)+&*!!#%"')++"+'$&'#&%'$)(+#(&""*#()"%*(+)!&*)#)$#&+$!!"!#+*'%)$*#&&%*%'!&###*"((#'%&&&*("&)%+&*!%"*%%&+!()$$*!$)'*&&"+"%(")!)%+##"+#*%)%**+
@r4779
AGGAGCGNGGCGCTTTACCTATGGTTGATCGTGGTGATANCCGTCAGGCAATCGACCGTTGCAGCAATATCTGG
+
%:/H4G78.-H;F=#D+C>"!+HG-*!H/.%%')8$AG.,C"2/!6:4-F,588-6B;%@()8"HD.1,61<6B
@r4780
CAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACNGAACTGCTGGAAACGCAGACCGTGGATTTCAGC
+
76+(>B9$F(?<F26+:4A8E"=>F=%!)1G/9-D3A15DE=#@*G!2,/032;19*#&F":B5/:D);*%30A66=E+
@r4781
GGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAAT
+
)6,#3+8G#8*H*@E//48&'"74+%D1>*3@AF1'#",(/2A3<$:E:G!?)8**?;:-!5EAE'/@>,H)B-13E@*BE<)
@r4782
TTTGAACAGTAAACGTCTGTTGAGCACATCCNGTAATAAGCAGGGCCAGCGCAGTAGC
+
G58!9)B3H0%?>(#4/:"C&6E3H3#F)H*3D,AFH=<>$@1-)4;B.!;5+$4/.6
@r4783
NGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGANCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTA
+
)51B2AB*D$76B?'**<(1-8#.=93?&6196'<-<$+2@>5E7G+C#HB$(+4&8-F#,"E69#,"2*;/F"53HE5$#./A20E/;2>*!;0=H&.4F%3AG'#?DC
@r4784
CGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGACAATNATCTANATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATNTGTTCTAGCGGGTTTGTTTTTATNTCGGAGATTATNTTCA
+
?*2F*,$4B#0"63G0?$=B65227"@D10(<=D&83!*G.$A*+/C62F<F:=AB,1B5,"7.0>&-4(.ED>@4>(DH*02+7?)D(>D-0126()/G;2@B1F25&H147>81"DF5E5="01?<B#HHD)AG5+='(6#2@.'D'A18%;*5?<3(HD),0720#+*,A!&:D)+F@ACB.0&(
@r4785
TGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTGAGCCCTGCAACG
+
;E."FC(F@>E;D;CF#9;)G6C>@8@=3:#E5@B'!G<0B5%33?<(&G;
@r4786
NCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTG
+
#%=F)"5E3&1&6%9CH-<?C-7*E%2&A';8(%399("7.*!*;="@46<=9/?1F:->,@H
@r4787
AGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGCTGAGTGCCTCCTTTGTA
+
9;2C#9+7B'2H7?C)@@5D#D3@6%$*)3D5'C?+0(@),7;"1=!")!=A=)9A5;3%9)+=;.*9
@r4788
TNCCGGANCCGTTANGCNGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCA
+
($&##!(!#&*!#"*%#"+%$!#!"(!!*&)+)")+%+(%*!"%$)&&)!"&+#)"
@r4789
NTNGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATNCATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACAAGATT
+
&$#++(*!&$''&+*$$%$+&)*!)#)!"*+$*($&*(&!%+))"!$(*)!")(*&"'!'##()%"%&)"*#+(#(*#%"!'"')%)*!*+)&*%)+%$'(##"(+"*%$&))"'++'#$")+&(&#*!&"($##)&'&'&'%""$%%#%$!%(%!#"(#%()'#)&"+*$$'$%(
@r4790
GTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGC
+
/H9*E-36&*4.E"$D4+4G830'.FF!6;0&7(*H$@!)$5<:26??A(%94%74B*G#'&-1<A'0599(#70('2+B5C@/+/<5
@r4791
CTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACTATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAANAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTNCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATNTTATCACCTCTAAAATATATCAGCATCTAGCA
+
(195@>3#*F.,"8=)",20*(AA9$6?:=(+<?A7*:-/H>3-))%,F%!)07:0H4=G&>#B@+!)G'=?@;H9?@/0(74869':<"55'<C6?=9:8&73/$.<%:E05"+G,1"+H(8.8(,-6A!=#+F"A:'(E<;=A+E(0;)>(,*>5&%#2-$4.*0;@:"1@5,C5+:F@&90G.5%%#B-")5.&A/<$*7B:67+57!/=!%D3+</1/B-0D+<!)<B.E:%D<*B04!49"&F<%'945&30E*9>82<-=!$<+!(+494%@1#AGE<567!%=D9CB=@)8F5F'E*?=3E+=0;;04G#08'B3$=4-?!
@r4792
TTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAA
+
+G;,6&17EG!2B=5<+87-?G)G#&A47/>@7$(H&2B<?'(@B+A)#EEH@&!9*
@r4793
NTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATN
+
$<:702@&)=<B:>G<@>H7$09')!.3>5!DG*<G<&24::-0&%<95<H0#7.0A.E+
@r4794
TACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACGTTNCCCACCTGCCTTTTAAAACATTCCAGTA
+
)+"&("'"!'$$#(%#**"$*&&&'('+())%*&**!((')*!%%$'#+!*!*(&)(&&(*(*$'+)*('**($!#()&%''$&*)&((")!++!
@r4795
CTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAAC
+
HA/@=,98F?"&(3/=6:G8'E3";G7/+&BC*7@'-@><(#.(=:/A&
@r4796
TCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTAGGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGNATAAATCAGGCCGCGGCTAAANTGGCACGGGCACGTCTTCTGGTTATNGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGNGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCCATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCANTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAG
+
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
@r4797
TTCCGGATCCGGGAGGCGGAANAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATNTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAG
+
+1G$,F:)3HEA2'94/%D'#;G+>"-!74)7=#5E8CC@*#(<5)219:5"6:=.6-B@F%6(F(13&;6")8-@@%$"#-!(<-,!%%*:6>CD/'D08?1!'!'H(G$C.@@;-,.>1@009H**C+/F.<@
@r4798
CGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGAC
+
86"#E/*52&$A@)>&A>$HHEC"2/+4:)-@+'>$6./"4:8<.%F?9#:B4BC>?11'2$5!?H0/$BC/B+H7D:H1)@'!'+F"4H+/%
@r4799
GCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACG
+
2E<(A<"/8":$%<F4F0>G*%D46*->;%*7"0%"4.5E:C5'99105?5'HH)*C'=&%(#E#%BH.(G%'8E87@D6>)42DCB3)0DH$+&%=F,!-*"5C)E;<E
@r4800
NGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGG
+
#2,67?4>B).:!F/3&>*0>*#%0)0,/94A*28(G%E7+*A14(B')24@<H$DG
@r4801
NGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGAT
+
#@D3"5E6H4.;HE/H<!"/.3'(:H39=2;,A'+9D@-/+H-9$#05
@r4802
AAAGNCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGC
+
$)&5,&8"(F-2#<='(22C8+!G'44%(+'17:'2148F<1<7
@r4803
CCGCTGATGGANTNANCCTCAACCTCAAGCCAGAATCCAGCATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCACCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGNGAAAAAACAGGGTACTCATACTCACTTCTAAGTGAC
+
'((%'"%)"))%*)(!'"!+!+'%+(&#&*+&#*$+!'%#%%*+(%&*(+))%''"()!+"&$"+(!++(!%*%%*""")**%"&$"&("%!$$'($$!'&$*$&&&)!"$"(!''"'#%$"#&*#!%+!%#%&*"*("(*+%*#%&)%+!"($)"$&**#%(&)&)%&'&
@r4804
GGAAACCAGATTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGA
+
":'H:,:="4/)&35H@G'#E%D0!):>9&BA>42.C("/B2A3D(1:*3F7;"9(""21C36;%-'F!#!=(
@r4805
TGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATA
+
$-3%H,73H:>7(?$7C/+?2>&D<3?CAB=9!8<,(4G@&+C)>4"--CA'7?7$EHC=3?9,;1
@r4806
CACCTCATTACTTAGAGNGGTAACTCTTTCAGAAATTCATGGACAGTTCGC
+
89/49?+A$DC4=:731"'!8'(!-72H'/.":-6B-FA*9)8>H*8(<G3
@r4807
GAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAA
+
#=&-,3#9.*9;1B2F1:E3>7%F7A>9,6-:D9G%:D%.B$G>D/E"&;!G,55'?7&"A&C#+G0H-$-6$AE,HE&#,-GF!G
@r4808
GCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAA
+
?)FG.86'"4H64"3A%"63-3?8;/):'H:,/?&/9%73<:1#1DE:/2*G5<9"'D6D@;!&4/.BF$F9+"D6%G#'7G0<1C2*>6%!E<4C2#+)G9+$3?ECC--D!-=A"3
@r4809
ACAGCGAAGCGTTTGATANGCGAACCAATCGAGTCAGTACCGATG
+
)#$+#(!"+&(#%()"%*"%#%&#$)%$"+$''"+!%&#&'*#'"
@r4810
GAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACNAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGANCTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCANTAAGCAGTGGAGAGCGCGTTCAGAT
+
=A9D71=2(84%3=855C.!@,!,?8)!*E7AC68='#719$-7G;961371EG+::#/8C+2,648#-C3F6C&065(G6A-.G+8-E)$F1H>/:DF#A;=)=B.,;#23("*&5A>D1,1,,;&D$BD3)"5".;E.?$DF?5(4#)E56'=.)/*1>"33F;94'<@$+E?&-;97F.+A1=37H41?"F.2)?)4-8>>
@r4811
CGTGCATGGCCACACCTTCCCGAATCATCATGGTANACGTGCGTTTTCGCTCAACGTCAATGCNG
+
(F3E!E/>1?D28C9.G-)/(360;*,1<&2C<&?(HG+C"%C(5(9E;").1)#4"7.D$HG9A
@r4812
GACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGNTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGNAGAAATCTGCCGGAGATACCTGCTTCACGCTGGCGTGGATGCCCGGAGAG
+
>#/,'$E'&E39#'-7@E4#.2!:#(<.B,--B9C0=#GF@&="GB>;E1*-*<!*0=C#,2*;GE9HH<0AC(CD$51'D==%3/&>#:5:5:!$($D.D#.3#&!%-452,"G3@#<31D-5/A>75!!*+GH.4#<?4;?,:!$!B:&)1-634&'19D*0B78E>-'+7.)7070E/E2)%>B04#""&?#+;).E?,
@r4813
TNCTTCAGNANGGAGCCAGACGGAACGATATCTGATGGCCACNGGATCGGCGCACCTTGTGCTGTTTTGGTT
+
&(("))*)#'$''%$+)!+#+'!&!)$)(**+%#+$'&!%%)"$'#$&)%'!))*+(#!+!!#&)##+&(!&
@r4814
ATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCT
+
%)'(*&''(%$+"$'+*!#$(%")#''#$'###!%)%")(%%'&!&&&)&$)%#"(#'!$#)"(("+%!#$!+$!$*#!&)$("(%)$&'+$)))%%!%&#&)%*&!!#"(**)(&%&%%%$#+*&#%'&)"#$)%#+*$'&)''*'#&!$+"&$*+)%&(#!*#)')!(*!&'')('%&(!'&+'+($('$(#+&'+)"'+"(+&&+("%'&#*&"&(*$*!$(#+'*#(#'$!"+*')($#!"!+%&&&+!%#!%(%##"'*+&*&&%'*"#%#'$&#!)"""'!''!(+"+&'&(!$&$)$(*$()(&
@r4815
CGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCNCTGGCGACGGAT
+
273"4=GF/>4:=D080+=15$-$94E)/8(D,-%H&(H4.'&%'?BH
@r4816
ANNGGNNCNCGGNNCNNCNNTTNNTGGNNNNGAANGNANAAGNNT
+
$"!$$#!$""""$$$"!"#!"$!"""#$###$"#"#!$####!"$
@r4817
GCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACANAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGC
+
/@.-@<=H!)%+<0,-;GB2'89-B%;*@,%?9&6+1=&;@;$=1/E25E9."%4;"3013#7'*AF1&##">;5E)A'>5%GH61@9F2@@?<7(C0&2/3C8165&@6)4:5!4,9A6#<>+E(B,#&?;81@C).5-EC2G1%AF.'!"1DB&
@r4818
GTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCANACCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGNTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGC
+
,8"E/<4;8&9/@A8ADD/3A;0-9.A7%.+*#?*0E7.+#BB<C;#7A1-1&3H>8;@8E04+,)=!G1DD76<'$/53@DE@D)*CC?.;&?)B?F*>;:8.+@1E(@0?D?A*-/&G+95H:C?<H)*1!)<E*?"(?'5@6'2D*&##*%*=9#$?,GC,E"@D+'6%3!4>0A;GG;EE:1*212;/@82=FD*'&"(F:!9F&6A=/$:3,?:-57+=D%
@r4819
TCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTT
+
.>3C$*@!C@-3B&F?74F53H8CE?-%78/-@9"BHA6-9FH<,)&8&43"1*F625.B9
@r4820
CCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGANGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTG
+
*>18AH96)+G24!;>@*"H75)?6C$0:-#'>HE061(423*@!AE5B"/F6F%8,$!-%$#5@$D&43@-92,/G10"-9)+06<96BH$#55'=70%94>$3*/%$"##<F%*69F*4747F25>(:>=,(-*?)37&%(B49;07*??<1=!CEFB6:8A."4F;:E,&720-F4/55-?D/40H<'%%%H7B=6A(D'3,-A*<F$)"GA9*!2@!E07.3/#</B+,:-A!<#7&H-!"H9*4??6&.!*3)/,*?/%+0#8EG=-,4;CB<-'5/C;C-E"-AA!9/;;9G4$A=B-A+!'#602E!AH4<.#:"0G?/,'):G!793.<C/5&5B%<"880/'")E4!?1:B&G)4!6,:(4G8'#/5*:(CD92+!2@544;'5,*"C7:D*%0=>33!395F
@r4821
NTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCNAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTAT
+
"=5)G2!C&7.CE;FFD5B-0C;G4>GA794!;121HE0&$B0-7)/?6?&54&<;(-@<3;EG1+=?"FH-2$,,E%((/%$:.17<?&;2.(#77;2&3G6H'@4"#@9BB(C$;@#05.D">A$-"H,"C2%BG%+*049E$6)5:,+<A7F+(A+75!+)("G,CA"@H%9=7"<B;
@r4822
ACTGATCANGGATAGCGGTCAGGTGTTTTTACTACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTG
+
H7&HA%0#FE+?H)+9*D7%4',86/08+=E0F:.&D<C2A$0/2)-".@&B?G%G6D$,C9)@6A=#$D9#;(-A$,>&$;?#6.?233
@r4823
CTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGANAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTAT
+
EB-@:0H=#0!E>B)3HC5@(>H;;30=9<F=#B.D(5:5'!%@4A??&1?#4G<"%)%0.='599,E%1>=,,.AE4F+7*9$'*F-9*(<@A,-*3,D9$7?9+;>GE6=+;0EF)1>@
@r4824
NAANNNNNNTANNANCNACGTNTTNCGGNNNNNANNNNNNANTNCNNANNAGANGAT
+
!$$!!$!!"#"#!"#$!$##$$#!!"#!#""$"#!"#$""$!$#"!!$!$!$!!$"!
@r4825
CAACNGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTT
+
(@*E7B(H88BH!$/?-F,%2&4B11?6B*H-DC<1."?<,;%9.0!H?E2$52&C'D
@r4826
GATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACNGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATNTACAATATCGTCCTGTT
+
34CC6!'-BC'951:54E"9>DC@BF;@>:7*H(G7F=0-)C"D5.'%!6H3'B/.>)"D+1F1'04'$C)22'%;-@'A1G7"!B6$("@<!BG9-7->E<9>G=H2(281D&DB.!0@E!*@.,$E+.@!/'G?->"3$G<A
@r4827
NGGCANCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGC
+
$**#%!'+*&'$*+)&*+!+$%("#%'&!$'#!"$+**"'!("&*#!%+!"&%%&')*)(%*)*!!&&*++%!
@r4828
GTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTNAACGGCGACTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGNTTAATGAAAGATGGNAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACAC
+
**0-G8H#436:6>2'2@H8-8#=<2?7H:#>!+A&A8:<4<%D:+<E$0-E6<?0$/!E',A6E"'#1H<)<2#6%:E#6B$*<#1)@"7=?9B1-)4'3?"8%.F)3'#97=#*8-5F""-$&8@+'"(G6E@D-#$15H4-,&?;.;2"5$0!&9F075=6+7H@)=:/75+3C%/((:#D#16E>(B:'E*):6;5-D;1%2G$D%2)@0$-#.C%5+7<5D&8:5F#?23B@=?F5G%!!'4#74G&0F6F%G1##@='2@A49EG?#&)E#&BB**)>4;",:;&:55#6%C(7=9@72A??*5@,&119EA,GB"=(5847<
@r4829
GCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCNGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCANCCGGACTTCAGGCCTGCCANCCANTTCCCGCGAAGCTGGTCTTCA
+
AA8>!F+2:%+"CC;%55AE!->2;D7;!&,?/*@C)A;*F143482D*).>1C$D,>!62.2:B$(H&,E/9F'9!C"CBB(<D"F5;$02'A0&!09,"'H,7<?H,="976/(*$?D(?*@*C=3.*@;.9"6*4:(H?>B1A/!')'";DD,*:F?)#D?7.#6>*CC$91
@r4830
GGGCAGGCAACATGAAAACGCATAAAATGCGGGGAATCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGA
+
6'&(@B:)?%>7&5(5.3G'E+D9:GH7C><(@(F.F2F4#4A@&@"G.HD5A/("?0?HF)##H,A)/!5AFA1.B#6)@6#8HG24F&G+(:
@r4831
GCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATTAAACATCAACAAAANACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGT
+
A9'"+*G#B#C,1=G)?!<:5?D%57D:)&,-D93"1D*@779*5!*.D0><(;.#$-#5H:?!8,:3=:8>:CF5*8-@75-@.9,3%F=E=#H1@-GG+19+1E!D-?F7,+11)>@/.?&)D5!DBH?F('<G4*:18"(#*:7!@%D&/
@r4832
TTCTCGTNANTTGCAGAATGGGGATTTGTCTTCATTAGACT
+
*('$&%'*#!+##+(()*'!$"("")*(%#'(%#""(!(*!
@r4833
TGGTTATNTGTATGTTTTTTATATGAATTTATTTTTTGCAGTGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGT
+
8%:'8)9(E-D?;)#0$:#@):2D'B()<8"G0="57;38!%%'+6"'08B?C6,:'@=&?"D8:42.:#@3=-/@/*,'-HF8B="BF6'
@r4834
NTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGA
+
$76#B$4?<#.F2@")31=>DCE6=D:4,F?2<02?;6$1"3;6#+$D'"72-,8AECD;>5+
@r4835
CNANGGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGA
+
$'*!*++%*#&+$(&'''%&+#+#)!")$$*&!$!'**%(&)#(%(+""""%
@r4836
NCNNAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCNCTGAAGTGGTGGAAACCGCATTCTGTACTT
+
()!$+')$#+#&$"%+'%&""##''&))%**+&'#+++&(*%++!!&($#&('+)&$")'"#$()+'()+"*!
@r4837
AGAGACACCTTATGTTCTATACATGNAATTACAACATCAG
+
=<-F$7A<3#@7&(C!*-#;B7#A;,15)">!)(1046>%
@r4838
NGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACC
+
!'CG;2>B3@/01<("H4%2=H=,!C85=76*.&>-'DCD3%4H7AC*!/+%7#C=5G;@671>3E8-&8G5F:E"0H!)7(AC9<?D98GH5B;=
@r4839
ATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCG
+
&+*&%$""(#''"+%&'+$!*&%#%)%*)"'&%"!)'"+$#")%)'%'&$%#*"!$$"!")#*+'+!%$&(#*(
@r4840
TTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAA
+
9G)1,%2:8D%6=1-0,/!%'>=F9F=!/A/=4=FCE6/73.@;%#$/!5'>=?F@<>F);9@#+#+81!'5+41(!2)G.&$="C-?7/2&2@*9C;*F<;3?4H-@-&'=7A#(1@-*39F4G:H*.3'4*+AGC'"=/1?7?H(4#&+/$"G2"A?4%D@/4A(
@r4841
ATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCG
+
2#55G1973/$&2EAGC.A3C7)BD43-=54/$:=$F)&#1F,+1;?$-*1'2-:A@!%<%@&FG-&!5
@r4842
GTATGGCGATAATCCGCTGGCNCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGCGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGC
+
-36=$>8/:?.$,6C5%1?45>;,!0+G"),,B'.DA%3.H;)',+H@F?=H*/"C?B:2;!+.C=>C"9<011D'B@&&474B,2>2?+3GE.DA#F%;!'>&C(A55%5'+&;/051!A:/."4$GF=C;F3C@-:"87-D'2-8@A*8.:@0;.4H,@5-&$B:75C)8B@59BHD8C;:'"7:9@9D,+@6F*EB;!3+E:7A#.=053++C#!363(37/#BC.--?,*(@.+
@r4843
ATCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTNGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGNTTACTGATAAGCTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCANAACAATGAGTGGCAGATATAGC
+
*;.!(G".6;!=*:>G/G8$.H(A<)-:%H?96G85F%)CB6,(2>&!A8(D&"*-<*=84:1D(DA%H!(?(%$?'H#$?D9<!"<FF'7H@5#?/#)91<HH:4E5$/:H+@E'+B-):0H;B#9$B"7G"$+->65(B56477#43/&#(<A:$&!0=$H@7/:CG>4H/2+47F$5-*#9D86#5,HHHGB:36#+C4@*1"<,;B81G'02&E62E4H+989H:'0%"A<<=4!C)>3<C/,:">G5E4B242F:G,(
@r4844
TCCCAAAACTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGCCGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAANAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCAC
+
">!%!*$/8=08:96/H+@'7:E11*8-?2A&EDF0"-*81?/,3:&+>18),.02D6"247-@A0>5(;D"-:D3G/E?:6'#E4<;!*+(@GF")6@:*#*0;H-/%%"E6#-:4%'H)CF1>3@%G$C2C%..FEF!;6+=").D%9&4@21/6"6:%%%4)#=GA7>87(-3"645/8.B<?!!$::F1:+C",EF2(58!.+A,++/61?D!:1$;3&%>8HH'A<#3A.!A*74H+E&&.->'C%AH&)2/)7C/.&8)4830C4=3G6
@r4845
CCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGT
+
&B,+5>;2!(9,4@&*-!<C<%6,17;&A!D4AE"<@#A&=1/E*'/-=")2>+<C?=$C6,@!G9D'.:'C<!G+E+30@:#%>+$9,46*+%@/,;94=>:F'C>>-,-F#95G=
@r4846
TNAANAACCGNATNNTGNAGANGNNATCNCATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCATCCAAAGGTGCGCAGACCGCGTGCNTGAGTGTTCCCCAGC
+
(*'%%#!"*()''!&'*$#&%#)!%'*&"+#)(+($'"))&$'"+"!%(!&!+!#%"")#*%"#'**#)+(%('%'*'*&$"*$"($%#($"$*&'"$%($!)##"$%"%'!)*"%*%#$$"('($#!%&""&*!*($#&%)
@r4847
NTGCGAGGGTGATCGGAGTAATCAGTAANTAGCTCTCCGCCTACAATGACGTCATANC
+
"(0F1,F*A#F(32)<9"++A@.3.GF/1'H!$*;(+3=@A?:>%>8C=?(@-2@G;*
@r4848
GGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCTGTTTCTGGTTTCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGGCGATGTTTGTGGCGCAGGGC
+
H:8>/5'2'63E5@A+1=,HD!1$:";9",B;5H8=0,%0F>,/E)7'/C"=67A,?.D.2?/B(,C)69-38!A:6F"<;264&;+160$.>>&&$-?#">*D";&6?H$$!,?;C4)&AC,4G#4+?".(A;#(6:<3=@+23/E/B#+*/CB<B-4CB'=+C.*6&:'*@95:7(=&)%/3=
@r4849
NGNTTCANCACTTTAGGCATTTATACTCCGCTGNAAGCCCGTGTGTAT
+
!#("*"'#((+)&%#"(*"&$%!"&!&&''!*+*!&!(#"#"$)($%*
@r4850
TCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGC
+
?)0H"1%@066'...A1;<>!)0:,0/.&F16@!?,"AHB0.G43?"5+0#0./:E#&;""=
@r4851
GNNNGCTNNCCGGNTNNACCGGGTCNNNNGNCNNNCGTNNNNNNTNNANNNNTNNTATNTANCTTANCAGATTNCNTNNNTCATGAACCNTNNGTANAGNNNNCCNGNNTTTNAN
+
$#!#!#!""$#!#!#!$#"!$##!"#$!"!"$"#!$!$$"!!""#!$$!#$#"!!$$"$"##!$#$$!#""!"!$!""!!!$"!#!#!"!#!###!"!!!#$##!!$$"$!$!$#
@r4852
ACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGNCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGG
+
9GH@FGG>%*A655-#7A&)"0!'D+<15!7B$G082$<6"(.;<H.4.E;;@=3*'0@79#0@%-&483+0FBH47FE@6>4E96<72/E4;>A0&9,1%?:+A7B28$0/H2H?3:GBA>,:3+D?0++#@?$1';E8@5=%'582?G+
@r4853
TTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTT
+
/-#?*#0&(;;./3'&6?A:#36BB-7!C3-))9D>1&A5F#BH-7"%-%:?:@G:>!0$+H25D?/G&H%:&93?'4
@r4854
CGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGG
+
3E&92:@(0>BB'1-!==3/:,(513G4042,58HA:=.30&9)5394
@r4855
TTCNNGNGTNACNNCTCCAGCGGTCGTGCTGTACTGTCTCAGGAACAGGATGGNATTAAGTCGTACACCCACAGTGCCAGTGCATCCGGTACGGATTT
+
!*#)!$%*%!#!#&##+)&%(&%$$'+*+)*"'&+#%+"#*#*'$%)'+'%*#+#+!)('#'(')!!)&"#'&("%$'%+$##"'$!+"'#!$($)*%
@r4856
NNCCGGNTGGCAACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGAGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGNAACCCGCCAGCGGTCGTGCTGTATTGNCTCAGGAACAGGATGGAATTAAGTCGTACACCCACAGTGCCAG
+
!)&$#%$"(!"'$&*+!+&$%%&')&'+&"((&#!%($#&$)$*!!+$'#''*"%)('$%*'*%&)#!('%(%""(%#(+%&++$**!''**)+!'!$")"'$*#"''&')*!'%!**+&"&%#&()*'!&"%)!&'+"&*'&#''(#$!(&+"&)')"%$)&(!!+%+$&!'!&!!#*!'*!!+'*'(!
@r4857
GTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACCATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTNCCGCATAATTACTCCTGATAATTAATCCTTA
+
=H#0>5==(,E3GD*!&>::6*>2*FC$0H+:A9'8&A:7B983,+-:(775=/8@/C@GA09A/G%"<GD9#;38=&AD4*>+5>BH;;/=>==F!+#24%#5?C0-!%F*5F+*&3$G%@%8.D5+/25/%DB+8"4(08>$!+6H1"88:2&2<#@5#F=-40F76A"&-%-#*C11H%5$1@1F5D/'FGFG-/'*1B!5:>99A'
@r4858
ACAACATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTC
+
01"H)$4+<+:F<-#D.*>,>DH>'(0A%981A=C7+>%$.#>.H'7&"<0#$C&A2;<CC4E,;C@<$"!
@r4859
TCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCANAGGAATCAAGCAGAAGACACT
+
7*#<(2?2<-D3)>/)$%/72'9!36G#AD(=+%A.G=A?)<;2:424G.HE;;5=8H.
@r4860
GAAGGAAGAAACATCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCT
+
::*0F5D/!;7#8:;4':E4>%H#*0;CCC!>?F;+=(3<5!.<<9)5<C)
@r4861
GTTATCACGGCCGTGGNAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCG
+
>C#73'-.F:8-'=::)'A!5>H8B#FG/)51!9525FG0!;3>?0#01:$:<<CCEEF73E'H.-<3&"!+D>B<&?4443#/0!,5C?+/&+G@'
@r4862
CACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTAT
+
>&2@)-4%F3@B1<<8*#-AC@=-3:-%)494?:?D5AD#;?(2EAB1B>,B5F?(B<?#+>$:C96)@?:"FD3+;*96<AGA3#(3'-FA
@r4863
TGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGANTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTG
+
H>#D0-E%6%+*8.FD(D<4+)6#F<DAD<'*%C<#2*,F(-3#>GB;%"3.,G&$-"40$E2>2D0CHBB<D<C&%&<E4@F?#7+!A=6A0,4E3#&C)08A.A?!+.4*)&#77C@:&B53)
@r4864
NCGTAANNTTNTCAAAATAACCGCAATTTATTTGGCGGCAACACAGGAGCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATNTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTANTCATGTTGCATGGTGGACTGTTTATACCAACGATATAGTCTATTA
+
%&")%'(((#$%#+%()+)#$''"+((!&&$%(*#++$#%+#'%*+!"'##&&%+""%*!+")*'(+%'*#$&)")&"#*!!%*%*#!'$$!%&&!!$!)%)*(''+'+#&'"*'++**+""(%(++%#!%'%+(%"&!"#'("&')!$$)"+(+("!!'&*!*)(*$*!())#!%%)*&%&+)+!%)'(*!'&)#"#$&+#%%+"$)&*!*&%+%&%*!"#))
@r4865
NTCCAAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGA
+
"%"#!$$++&%'!""$"'"))'%$("((()#!*&*!+!#"$%)')()!)*"#*"((&#")$#$%!&#$")(&*)$)""'"'$#($&%%!&&+*+%++'(#(!#!*(&%&))*#(*)+%#))'+&#*("'!!""*!(
@r4866
GCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCTGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACNGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCAC
+
*3;)E:9H8+C:0B=D;H=+$=DE4A=9D81)0.7H&).%%<3;>.+F1?E>08,D)0($#7!4B3;9F+@9CFEE47%482(9':@@'7=,H/,30;"C%59F/22C%9+)B/"*)$8;360.D(+B!*+=8DAG?4=G(F)&8$;/GGE/,&%@>CC+A%)1FH-7&#G%,4=@HH<&
@r4867
CGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTNCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCNGCGGATNGTTT
+
+$)(!#(+!*%#)%'($*%&"+!#&)'*&+$#"*"+%"'&""(+")#)%""")*((&*"#)!#''+$!$($$')#'#%'%$(%*!&&!+*++%)+)##")++#*'&)*$"("&+()'*&"'$!$"$*))%"*!*&+##+#'!#*&+*&!("#*+
@r4868
CGAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGANTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCG
+
*"(+"%"(%))%%(!%"$&(*"'("'!*$#"!'+$#&!&%)%)"+*%!+&&''!)%!$$)"#'*%!)+)!))&'*'!!&&!*#$+!+"#%&!()&
@r4869
CTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATATACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCAT
+
H;9&1D36$)@/C(H*=&?,,(!->=1->5G=?(%'*A>$0"F9(?#8"5DAG@>34!'4;C+!81A&)'5E/F(!'=9!#=.&0?"%G6&*6?D"*"9;%G6G->14):7@FH;G&:%)0;=@BH#6=8@BC.*GAF*?"#5+D.9');E1C.%7C0)(-%-$!,4>?*;.G+89:&4#@!7!A'>CD%.EC)C>:?"(&FGF.0H59=1.C9<!*G'878)CA#9;,&0--)#7B'2E@F54.6-7#
@r4870
TCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGA
+
F(*?/H,H)#/E'C,'&:A+D<AC8CC@G*:%@G*@&@,=<,-!,/C<-G.>?6!E><B"H
@r4871
ANTACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATNAATNTGGTGAAGTTTTTCCTCTGTCATNACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGNCGNAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAA
+
+&.G/E#;/@&&;&4<F6@111+GH8%*8>A#&3GF3">1'8A)%&)"-!)=.H?2EB<E)!"93;F89A@8.=,$22&;!3:GH'49*4,%$C:%38'.%B-;E7D7#B3$*$$G&+D!/$&(,DB%*:AFFD!9#,-6'EF/).E?.G/>A3B>81+:<H=#?FD1'!B==3>8$*
@r4872
GGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGC
+
F1DC8C?%#89-3AE-&,/#G>,G2F2%'?)032,6D97H9+?,08#+8"-@<(D,!A94(-F1>,3?)43432*/1/:4?A;E&)@C7C;,9!1&1GE(!/9##A.<@-06"G."(!/%$*=<%DFA(&>*"7#&G6&/2>GH>:/(8;#?840!BF/<HE!@'F<D6>/D5/&900BF+G6&%9)
@r4873
NAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCNTTAATGCTGCGGTANACACACACTTCCAGCTTTCTGCATCCAGCCAGCG
+
.C+H$58,B25#*E-!6<."1BF)//CFH897"09#CCH?&'8=$=(C+>#1;"C*#B;"/3'H>236:F3%+C&<%HC9*.49=!9;A;"
@r4874
GAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCANTTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGG
+
(+!($$(!*$'$"$#'$$##)*$*$!+%"+&#+#*'#$&*'%$+&!+#()%$!'$"#%#$%')&$%+!!'*!('#!(+)+%*"(&)&"+#))'*"#')#)(
@r4875
ACCATCCGGAACTGTGTCCGGAAAAGTCGCGACGAACTGGTA
+
4F9>=<!1&9@F26,71BDD4GE5E2>407$0CGG)25$3(?
@r4876
TTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACA
+
%C<:8'G$D370!,5#3/C;2'E<=,6%!20%<=<3G$(8D$>A&*E;
@r4877
ACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAG
+
E@+81AEAD6G2@!9#G?25*D8,402$E.GG!$D#F7"FH$HD-%F2E:7>%F5-AC&@269>=*HBHHD6"<$'D8#:C<1;";DA"%6E*4EF896-4-&C
@r4878
GTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTAT
+
%-;470!(5F1-HG$")G!&(-D=E@D#+>CC8,?;0;7*H;45:*5!:))?"F"40+<'#4("4"7390!!->G&/(+9D#3H%"?(=.7A(;D7/2:A8.*E882?;8&4:G%!3"B77?(9H=6G58B37?('%26?;"1@E6FG%2)5C?"*?=..5&4-5-%$05$
@r4879
TATGTCGATAAATGGGCAATACGAACGANGGCAATGNTTGCCAGAGAACTTG
+
:>D'6'(4@.+(31?:62&<9,0&.1@>03934(D3;E$F55F-G"%10E-<
@r4880
ATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTNCCGCTGCCCGTGCGGCA
+
&'$+&$&"*$*%*'!*)*$'(+"!#%!&##+*$#)$(!'!")&#%$'$%#"%'+$#'&&*+!!'+*"%%(
@r4881
AATNTTCANAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATT
+
6<=9/4>H53=87$&:+=*3?&)$7<(>:"58)8)?3=?>FH948!*G9@E0-=?D-%+)*?0=B>3&1E,;F><
@r4882
CCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGNCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATAATCCGTGGATGACATCCCGGCAAGCATGGCANGCCAGTCGGGTCGCCCCAACTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGT
+
&"-A9GE5F24A/+--D@8@,$BF)"B9>(-)/54D&H%,C1,,725#<*5:C:/3A2/2-/#0)GD#.(<G/3H5/:)@#G9);0B<')((%*9:E'#%2;$5=+B#29$.4>(0;4#A$$#F#2C'>F("+12H2"E/G&C(G6%(F&9+A?312EB*?1B?/0C1(=GF0<),D/-5.1-.)F),)=A6B)DFF5D/)F!>4-3G9/5717%C.!7&7%+1!@:%0&3:';E&6!=45(54!A(G#$B$0.:/'#E&8140<3.E"&=A<";C$+&>%98HB=$@(?6=;$;5#DG%60%,0:H4G?.,)+%(H8?B.)91>"C-?D!?C;6!BC0:'
@r4883
TGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCA
+
!A1"GH+D#9G$/,F(%?9=#F<,-=1.B5,>0*"1/F$F2&41F-H?=@BGA5-#B-D>-,%*>?DG?='$A8/G*B/<*1F+G8=)
@r4884
GAAATGGTGTNGCAATAATTGCAACTCATTCCCCAGTAGTACTGC
+
)$+$(%$$()(%&$%&'*+('*!(!(#($"*%*("#!&'%*+&'&
@r4885
TNCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCNTCAGGTTCGTGTAGCATCNGTGAAGNTCGCCAACTACCCAAATATTTCGATATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTNCACTCCATACGCGATGAACCATGAGAACGTCNTTGACGATGGCGTGCA
+
"#%($++'+*"+!%!'%+"!$!#$%+(#%)%#$'&%*&#*$"%++%$(*)+&!)%+%#!!'""(*&#%)&%#$+#!#)%%%*'+*#&%$%)#"%*("%&%'%(#)##"$$*"#**($+$#(#($%#"#("!%#'+(%$+)(#*$&*&$"&%++")#+&*#(#)*(($%"!$")(&)&&(&*''&%(#%)*+)'+"(&#%($&)!+#+$+%#"('%#&!$')$)#(%$*"#'**'"!&%&&#''$'"*%')!"'&*'+*++)!&**((+'++(($$&
@r4886
GCAAAAAGATTGGGCGTTGTCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAGGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGTTATGGGCG
+
&"'(&+%'!+'%$%#$+!*$!)*+!&$$$&($!*)'#)#!+'(!&'")%$$$")*&*)"!&(%"+$*%&$+$*!%!#($((%'%!""+)#')')'$$!%%('&$)!(%'(&)&*"(%'&("!)!($$'%)))'&%&&!**+**&%)'*!+!"(!)*')%($*(*)#"#"*+$+%)'*&+#'++#(*#"%**%'%$#)+'!++)$$%!+%"""$'#'*+("(#)%'+#("*("+$(+*"''+*)%*&+)!&+!)#("*+('+'"**!)!'"!"$$!+##!+#+%$+!)**&#)$!$)!!"%!*'("*$#!+#"&*"%#$*&&''*+%&#&%&*!$&('!('#+!)(%"#+#$')###*+)&*%&!&)"'+&(**&*'%""+'()%(*&*"'$##'+'"&(%((+%%&!!!"*'#'#('$'"#$#%%$!#("+$#+!$
@r4887
AGCGCGTACACGTATTGCATTATGNCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGC
+
>6.-!E;@3<D4C%"<"/E?2104"6"4)<?0+GG1"5%=,&0-=?9&H/F89<(@(@*@40!%H9,/)@/#
@r4888
ACAGCCTGATTGCAAAATTCAAANAAGCGGGCGGAACGGTCAGAGA
+
0B9DE9:G5?=C%08/,B+'1A=F+&D&/!'@,<8@"@&(2'A11<
@r4889
GAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGTATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCC
+
C?G('3#G3&G@!0374,530*%*::4<(8D=8?F.=*@-%1?/>%%BA9%15./*+-451?%A:AE($"';BE;68H'CC(H5G45$)+D<1#GA8;@7:0HFD8(9>-1;#7FG(&E
@r4890
GTTACCCCATTGACGTGGTGAAAATCCCGANGGCGGTGCCGCTGA
+
:=6&#'H.+D&8.8%0/1'A=*C(C62?->5&E')?1,=*E=&/7
@r4891
GACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGNACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGCTTC
+
&HBH.8:"F:7(@<DDDH6=>,F"85B;+=/::(3E5F@<GC<(/C%717-A4%"=8"@(/A@-$9740,=D'G!-<B*:#/062D.-D".1<G;6@5;
@r4892
TCTTTTNTGTTGTCCAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTACTAG
+
D$GG3-*E8;3E9;@,!*95';7<CD4?$C==@2H*,F4266':;H1B<5B-')):)H(6H9+;:%)?G"7'*4+2F26D2!'>1#=C@&,.7/'$!1/H=81<#BGG#-$-G#<.AF6F
@r4893
NTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGNTNTAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGACGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGC
+
%,@G4;"7BHH;4?F07-;'64&-4%'7E8B8G-98/H&5;7/;EC'#">D.1'6&$6B6@2#@?"7F)F3>7BA>)G*.F/:G1:1;D))(&)D-,=.D6*00F2)B&(3E+C("1#5B&.$0GHE39$&?+'1>@(##3$,H;$#7C>/+<#!C:A4,:7F%1:6)/-3A*=$(45D6A)$'?A$@%0/:+5'"=/"8E$6:7#1"<:CE8GB%3,7!C7@
@r4894
TTNTNNNTNANNNGGNNTGANCNNNTCNNNNNNANNANACNNGGNAGGAANNNGNCANTCNC
+
####!!$!!!!!#!"!""#$#$"""$$"!!#!#!!#$!#!!!"$!##""""$!#$"!!$!!#
@r4895
TGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTT
+
630.GD)3B,@84);)@+9?GDA57%.=E133""FC5<AG@4<0-#.A&3A17:.+9?..#6HB,0H?+:9D:<+<'1/BB-?#+.&$8
@r4896
ACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAGCTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCC
+
-(9>508G..HEF(-:A?:.%672'/,8&?2!H*;&8/1-::5>%C'(A&F:'?)>C%F/CC&;:%'AECA.,:+4")C/+!0D!8'.G5(+6A64.)8/4#39")5D*)D73C?/:"FA2;3EA4E
@r4897
GGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACG
+
=F7/88G<8732E@%5EF=.D$(G";,G9).".-E:F5>2)9%4-=,:)$0:''--++68'#3D%=G.,-B,'%'"*=<;!C5$?#%!F=5(47*%:)
@r4898
ATGAGTATCAACGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTT
+
DG$-!;7:68B6.)36CE"6E17A6(F14+15D4.E.B?(DG$E633#B*%@D
@r4899
GATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCNTCAGGCGGTACAGCCATTCAGGCC
+
=A<!479D"@8A!.#$E8/(..93*:>+3-4;1*3/AA2('!,00F@!@44*@(1=?%"0B?A/$H!0=2-.C7@$H"1$'C31/7A;%!D=???,%=D=$#,=73,H@)G34!.:(&
@r4900
TGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCC
+
5A%2?8&7!./2EF!A4<?,&$!00C/C#CE(,/A;9/'G##&/>2A/D6E0813!,+",1:?)!>#B9
@r4901
NTTCCTGCCTCCAGTTCGCCGGGCATTCNACATAAAACCTGATAGCACNCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATA
+
%+*)(')'!*&((''!!&$&$$+)#)'!!%$*$&!#!%%"#)$("*%&($!)'*+&%$+('*)*#%#''!*'+$&&+'&!!&)%#%#$++%%'%)(!!$$"*&"''#$%+)+#+%
@r4902
TGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCA
+
)A&;&38HH;(B;>0%D%!"(H;<,%278AB806.90<0*=@#B;#032#7@
@r4903
ACCCTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTNGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAG
+
5CB1$/<C@3<?.$H.;+!5A$3+619E2*$.$**;>CD2DBGF%-/:2DH*=+!?)3$21?+)9B@4H/,69>=9F?E)69?,3A@&4*>H;79G6/D="6;#85=4A.=+"-1:H&'A-,/G9G
@r4904
ACTGGNNNNNTANAGACAAANACAGAGCTCTTCAGCATTTCAAGCTTTTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGT
+
%)'$'&$!$("!(((*'*(&*!%(%+#'%$#")!**(*#))$)*(!('++*%)++!+##%#"$$'"'(%)&)'(&"#(+)$!#$("&#)&!')$$!!))!
@r4905
TCTACGTGTTNACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGNAACAGTCGTT
+
<445-6F>4(,.-.,/+5>03<3@AA/A<(9E>&2+G7/>'D&&(:',+3FB="!D<3*,&4&&+<D!3?+"FHC2#<!H%E"9;862,F-A=*4#(&,3$'7%
@r4906
TCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGNCGCGTTCCGGCTGAC
+
6+?61"F7"3&91")GB140#F=2;G+*@C778>=76'8.B)*(.?H84"(
@r4907
GCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGGGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTG
+
%3:;A,4=G",DE,"22=G&5<D?.DA3$G26.G$A:B$8+"1*)?96(#5H-==6H)/2@7&83"/$D+!976(;@&D"(4&G()E?&C1$:1/6#5=*<!%!3./<4.40??>H)-HA+0:+G)+4-/;0.7>8095%%'H4<&%!-/;<&F@@"A!?F<&(.,A'-4-
@r4908
ATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCA
+
A3#)8.>,1@-$.)$--/><4*,H!)<$))!%:GF%-"66DCCD*60;=FE#D';5&C2*)8:,*:E3,-0%?BE.E?A1D#;(6?&(H1""C=:%2A#:-.CA&C1*(C"!?!
@r4909
TGACCACAGACCCNACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTNCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCAG
+
-8DE5#3#(,9>BC(3.(49F?+7=>$B>-G<(C2:*H1?7$D9BF"7-1*>?3("!F#%G5//+*4",(/<3C5!C+D-1:'&G4@D0=D55=%4-;83D"5)EC>2!%F?",:E3
@r4910
GGAAAAAGTCGNGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATG
+
9.&)3*<-CA;"73>8+!<GCC/:?9,=&*/;C<-"$G8A<8*+44!4H<,.#E$0A=+=&'><-(-B8%.:#1,$0<#)C19'B6?%&<3
@r4911
GGCGCNNTTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTCCTTAAGCAGGCAATGGTGGGGATT
+
')*#$!&+"#**$#!+#)$("$!'$(!*))(%!*%)"""!'&"#*+$%!$$%"'#'"!")*$)+***%!%$
@r4912
CGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGAC
+
9H1'G>H)C"13;H0"'DFA0@3C903A3&:G+&57#!>3>$*'(+E>%#;HDF82DG#-.A5&%'+4!8
@r4913
GTGGTTACGTCCGTCACGTTCACGCATCAGGCGGAAATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTG
+
H7>2,(+G>B&!@'?.@/4#H23)@94?A!3#,(<8C&/>(,4(7*D<3.##;.H92#-E58"-?C%G>+6/0&
@r4914
AGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGC
+
8;:+4A+1+$:/>/)?E$@3(*/A'C22D,C7*8B"=.=2$'*8DE<ABB<-.."B>E!G<FH*#%A?++==
@r4915
CANCCCANGGTTNCCTGACNGAATGNTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTC
+
%%$$"'("$!!("'$)&#%&)'"*(%%+$!&!*("!')*!+(&&(('+)%%")+$)+()%!!%##&#+%$
@r4916
NGNGGNCTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGC
+
'*!*&#''+$*%%(%'*')!+'!**")(!('("$%#+!*'!'#'"'+*$$)#$!%!'")$*('(')+
@r4917
CTGCCCTGGCTGAGTGAGGCAGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGGGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGNAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCNCAACGTGCGTGGA
+
9D-:D0F))HH=>8B*8:*.+:%G9FE-(*+*,'.H!17&;<=.A78;+?-'A;F5/.B'E84C2HE2B%.*04&6CC;)5C8E9G@F;A%(AC""C1E/@"C8!H1C15=2.957:A+:/.7?<">2&!.*%26?G)"-!;A#D#D+=#+..E(FF:B."3@6<A6)%E=D6&,08":;)7.@G,9"32/"H8"D:EH!*&>!1>08"E0/B3/'E!337;4>A%9>0E$5(<)"8??>;;$+$@@?<H99C">+4E2H?"67G';5343=7#F/F"C#-4*#502A"=3..:E,+=:<32@;E39,+E9#H5&$'+@<73.@E4%6%2<<8EE044C$0&>4>:1!)"))4))316%)D7'C8,%5C7+!+8.:$+:-%E5/
@r4918
ACTCTGCTCATACATCAATCTNTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCAC
+
??>1B$67G'B%*7(),G75"!!59'1=9F7')+="E=7B2<>>)43<)*6@9"?<4A4CF>1;75=9</83$<CG2?+F"B@1@.:1*$5&3,E$;E(,(2-G9*>0A:*:#!')D8)4'44,.9!'(.:/)6?&D=&"-CG8<>E')-%7*(;G>3D$.H;1+D"$3/D(HEC60!F,
@r4919
TCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATG
+
,8#><F!B6EC7#'3?E+B02:577D0-/,>9*!<($/%33.H,=8?*32'9HC6?"*'10;H7@&:'C*6-GE6;(*>3')C18*1?$4(?5CF"!*H.(0"&$,H7>42@+:+&0?867;*G>F)6=*;,!6:+!B=/9;C6.-7!"+H+80B8>4F?:>8+:
@r4920
AGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAANGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGAT
+
&/016%H:$1$E%)'*=GA.6D:H2+<'*6'G).7:B*.C7?@BA%$B"'(6#0<&79B51E5BCD:C;"$21,<0:"D+==?$<0)9
@r4921
TTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGNTCCACACTCTGGAGAGCACCACCACTGATTAGCGAA
+
9278'>*A#*3"B)2.%5=%)E@D"&,>?(83'1E*D2+$/>.G17+5):6+,?F+4&<(E@$:,H'9G85<?"5+$(<(2*&:0HH
@r4922
TTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAANTTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCATAGTTGGTCACTTCGACGTATCTTCTGGAACTCCAACCATCGCAGGCAGACAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAATCGGCGAGCCTGGTTAGCCAGTGCTNTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAG
+
D6'030-F#'H=$!?6&7<,8/H*#9.H.,%"+C>"85:-DCG-E!*"*"-7;%-#5D('6=.0B14.4*9!!<4$G'+(*/)?*?A7=!8D23;<+-6#%/1)4DFGC:-)A)21'4"G1:=A',53:+#B.-(84A//D>.@;-.8/F6?+@.A052)?*>6A&9@#+6B!31G0D>C#A"02AD9'?%-4=C888!49&>B,56DD-6#71-';CG>@>@%<$4>))G'BB0D=G619E>F26C=516!C<!<0>@0C+23)H>9,7*0-$#6%23:F'811C$$A/5-"D2%GCD27::9;&C/*+*<+-60*<3!(>".&?&<B)+F82+>.G=9(.A')GG:%CA&;E"+4/:="C->!.??E$"A,'E
@r4923
GCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGATCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGC
+
-<;$E9:'%&6,A0!%4F!2';,/4?58)+%?5#/E.?+;$7#B!=)+4(!A<F;:@3<93<='5E(A.%,5==+B5>14@8%)6B$5@
@r4924
CCGTNTNGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAANCCCACGTTGAACCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGNCAAAAAGCANCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGNCTTCTGGTGCCTGGGNGGTAAAGCGGCAAAAAACTACCGTGAAAANTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTNGC
+
;"F15."+B?@(D,!D#@/D#.,@+$%:6$H")98&;.2)CH22B'535(F*)54E68&%'97'+F)G5;*"%=8/!%:B@#/3G94;7!.?31$AD/(7=!D"=2%7>1)$&(.-'8/4G,826GGCA3"3>!6>"H0;6E%3+#2E#!/'.)D5#;(;@4%;+*&<<E?CA6(,@71:H#1B@=@C/<+25+A*#*=B'23;>G7;3-":,1FF>B%-#/),=$G334:&/@G)/*"'461@A8"/=1?#F7,F7;5!4((4/(:BD8@7>;H$2,-938@278"1(99<1(""7($')-/7,0GF,!2)"!3;%3HG?%D(*=#H'=77<3>-8;24ADAF+BDA@(<,51%-)$H0++&#C$D(FFCF?:!5G1-!;>.".G#04,4<##"5DG,'C3,
@r4925
NNNNCACGNNACNNTAAGNANCGNNNTNNCNANATTANGGTNATCCCTCNNNNGCAGNNNNNAGNAGNCNGNNNGNGCNNAATTTCCNCACCANGNNATCGNCGNAGCGTNGATNGNNTNNGTNTATNCGTCCCNANNNNAGNNACNGCNNTNCNNTN
+
!!!$#$"$!!#"#"$$$!!$!##$$!$$$""$$""$#"$!#$""#$#!!#!!!""$!#$#!!$!!$"#$"$!#!"#$$"$!$#"#!#""$$$#!#""$"!#!###"!""$""!""$!!#!#"#$"$!!$#$##"$"$"!#"#!""$##!#""!#"!#!
@r4926
GATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTNAAGC
+
E?G1;%2*,8E)/=EE:$>?A:#A,=76'3$?%'5=6&9*)E,F3>G-A<'+(/+7.4";=
@r4927
TNGCCGNNGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTG
+
$!%)'&#!(+%#**+!%'&!+&'%$)*"*+#"%"%#*"$"$#"&"*#+**!'$*(!***)&(%'*%))$&++"#!+$'+!'"$(!$*+*$%!$$+"$!$'*&&$$)"+'$$
@r4928
AATTCCCCGCTGTCTGCAGTGACTTCTGNGGTCAGGTGCTGCACCGCTGGC
+
!?H.*56(=>,%!F$>H-'-+9",5--7(5857="H$&A!!$*G%;/31;3
@r4929
GCCGCAGCACGTTCCTNCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGA
+
&C)0?(A-D*.0=%?%$G>'AB<&%"?59;A78=1G-;2C'1*8#4@=#H$?94E
@r4930
NGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGA
+
%D,%4FF>G7H',%.!69#;//1BE.5).;.!$-%*"&%'8@G8&+/;,&"66@2D.(@D+#92@:(@:H%E0
@r4931
TATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTA
+
8@*F)+">#CH-%)3)?+4"773@+?/$G87F7,A+&57-.@8%#''&E83-1%)+
@r4932
GATACCACCACTTATTATCGAAGTCCGTNGATTCNGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAANGTCGAACCG
+
D%',-GE)1A(,1;C&#";97D%!2'B9?=,'D#,H7AF?2<()E'A%?FF%#@@@4*0F"H?H-!#29:F9B:*?0=5*;5#$DBEA0/@(?:89@HD
@r4933
TGCTGCGCGAGTGNCAGCGAAATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGGTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCAGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCC
+
21<6-A*$://+G:*7-AF7?4*AE3<9#=#0,C"3'G=)<=;#H8.C@E6*F31>::-F.))68*+F3<595F$BG/.;0H0?H=!0#<@1@-1/545%F$7C%H,0?H''H2"+-*@,A*"=''@)HCFG,+=G0!@3E@H,!5'3BH#CBE!@@4F9<*7+3@4?*=A<8@789?+GB<20!@3?
@r4934
TTGNNNCACCCCTGTAGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATNCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTNAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAA
+
"!)$(%#&+$%&"#**(*+%(&&(+*$+'(*#&+)""!"+("*#&"$%&&++"%+()%)#)!"##"(&"'*'($)'%*!%#")*!#')!'!&%*#$&"#($)!&)%"$!&'$)))'*%+"($$+$"#(%&&*$#)+$!)%('!%!#+!)$)"&$!)%('#"""%"!+&!&")*)'*('$!&"'+&+('*%+('+&+(+&&*+%+(!*'"(("!!)$)))%$(+*))"$##"$'(
@r4935
GNGGAAGCTGCACGACCGGNACTTGATGATGCGTTCGTNTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGC
+
,!:3&D=H<F1%2C)+$0#>=3:&BA='*B6>9&+"6"<3/"+29H6(G9%E@;8B,70.445A$>0*<A:4#C!389G%%)."A"/?+1$->0>0@5::%-67.A'&E2(8,<D4,G&B+D?#&9E%"275!,:0<
@r4936
GCTTTGAGTACGGTGTGACGGACTGTTACACACTGTTCCGGGANGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGNTAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGGCAGCGGCACAGCCGG
+
*++"!*+")(+!+'"!+(*#&')$&'%$&)"!*+#%"#)'"#%($(%)"++!)'%&'+'+#**!#&'$(%(%+&&)$%($$'&*$'#)'!&(&+%"!)*&!)$!$)#%''$&+&%'%+&!'++'"*$")+&$#!%&'(*'%&"%%'(&"''%($*($#"*!&'$+!!+'!$'!)+"+&)&
@r4937
NAACANGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGGCCCGGATGGACGCAACCCGCCAGATGTT
+
#2E?BC7'-1,?DC7%!0C->,*?F<*=,1EF$@.FB#7@*,*("H6*9?=A="06#B767,D""$G9%&?0H)38F=E-"058A6><,?(6!#*>04"HG"/1>D8()7D36D'F=7BG<F8(0?2!
@r4938
ATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCG
+
9*)5*!)+!00?G-0=%HF<41.A>9*-0"1'&++.%11)
@r4939
GGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACNGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGG
+
/E:!5>>%A)5@-$?)1*(&93;0:@B:1D$41B4$7-'$@=)!57D0+>?8"'76.C,A@:4!:."(?&,?)?7*14$%4)9G"7;H:.F31?-=7F@+E+9"<EFH<E,*,?57:5&C<:!75%'5/F$1H5HF8D/B$E>$?AE-<2!
@r4940
GACGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCNGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATCCGCGGGTACATGGGAACNTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACNTGGTGT
+
*!+(%*$(#!"!&!()*&$'*()"*&$"$'*!+$)"#$+#*"#*#(+*)'+*%)!(+"+*%&!"""*$"+'&$$++($#"'#!"#)'%%#*&&&"*!'''*'$%%!%#%!"+$#(!&&#&+*#$#*&+%$)%&'$!'+$')()++!()#++#(&(*+()#&'#&&+!""))"+%"$##%"$!+%++***+#')%&%#+
@r4941
TTTGAACTGAATGGCAAAGGCACCAGNACGCGCCCCACGCTGACGGTTTCTAACC
+
DE2%47%?!0(>+-224329E.H20!?%3'&>.;;$EA/?9G%$5A'"-'*2=06
@r4942
GAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCA
+
>+6/%F537D14A=7A6:2'9!7,0G9+H155(;)?=*%4/6B)@H/E79%G'8.*G<8%!H-2"1(,55.*#?'#:"<$5(H5(A?*+H'7E@C7#3+9BA8GFA>.0'+6!=$H<%)4')
@r4943
GGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACANGCACTGCTGGCAGAAACCCCCGGTATGAC
+
*<,BH#.,H.!,B<D*8%+9&)D8)174/(>?=62!;'&2D;#&8=G-3?$?4*%5;&:/-44985&$:B=)EA/F(1H2.:54<",+4<""1
@r4944
CTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCNCTCCTGAAACTCAACATCGTCATCAAACGCACGGGGAATGGATTTTTTGCTGGCCCCNTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAG
+
6(">H0.@2!G>*!-G,#;$FB)!,%5"((9<'8E5(!/HH-<CD%1)$HD'E.(+F%E/E8E.F+25;):"BG:"3<+E/H!5B*;B+4+9$1$-9@*;+=C57.F=(4E/0$?<>;8+>0(5AA@6'B.2EA/:0!82C$%$C#'.37@/'77,%2?C*/1.<%$?9*$@A7'B.E%+&28F=CGG+9./.39*=)2)D6#.+-@)7+F,HAH'6B.'@8)1>-).3*825.A+;!49HG".<3H.H7A?@3D6+AF(>3.662E+3/?A#?57@%892E?GAF6"@+5$#BA&==1FF-FDA,E*<"?BGCD.$E-"2=0AG.5878/5+CF;&CH(=.)5/%?(/D)A>4C68
@r4945
AATATCGAAGTTTTCCTNCCTGCTCAGNTGCCGGAATCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATTACTACCGGCNCGACGATGATGCGGGNTTGTGGAG
+
&!+&%**#%&#$"#"&!'*"!&#%#''!"+'*''''&)&!))&+&'%!!*'%*$&!#((++$*$&&&*('*$!&"%)*!%+$(+&"#&+%%&"++**%*&"#+("!**'!+"#'("&"**'"")%)$)!&#"$'"*'*&&&*%))+)#&"+#%*'*!$)"+&*&"!&#&'
@r4946
TCCCCGCCCGANAACGACGGCAATGTACCCGGTTTCACTTGANAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAA
+
:0.A-B;0=;'&%$-::20:HC:513/0CH"75*,52-1#04E1D!%D.-,%H5&DCEA%C-'G(-A@,-?3=@28'-41$%+"-2A(3,$@%8>7;;AAE+>3F2B5<H*,&?80
@r4947
AGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATA
+
5C*5F/C17?0?.!>>;@1E/!6%-:86F4B$DE&+83:$*"09;2)(
@r4948
ATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGAC
+
/E657+%.)C:-#$":G#-8B1/;9,&6/'&*05E9)!053$5*%1%73#+.F>GD"0BD><E#G,,:G#/*#H$@+'G?0,#+
@r4949
AATCNTAGGCNGTNNNNTCATCAGCTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGT
+
'))%$*'!!*"%%!)"""#+'*#%+&+%*"#*%"('$!"&(&)'$#%(%()"!&$$!'&$$%%)#""'*&$
@r4950
NAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGC
+
"8>F*=6+6)/*)45?#'0>;G6293H8(B>/0)).6<*6(H/)9$D9.&CE)
@r4951
CAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGA
+
>-G,/7@6=9?*H).E2D6"=1?/(0:E9!#7/!/-1>?(A+,@&6G@A3B@H52-=/;698.#4(+C.:6%AD
@r4952
TNTCAATCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATC
+
%")%$""&#&"%+$"("#'##'**")%"!"%+%!&(#(!+'%$
@r4953
ACGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGAT
+
EHD#.70%&(0%32+!&2/,G,=H$$GC>@(3G81D.-G:E926-%;>4C5>;5.7!?;=#;7%$D)G
@r4954
GCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCNTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAAT
+
+<;5<,%HC0D:!18C8%9:4!<3!CFE93*6?>$@3-9-/*4%7<C<,B7):(BH%,--!EC#26!)8A$H=?F.#0>"!7=*F-40E5:7F
@r4955
CTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATNATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCC
+
)$3?"=FD*"$65+/=7*9A187$9!FE1<302/'4;#8#:4=;-A,G#!/!8%H8841*2<!'.;289'@@1'@/899*)3$<4E*=.2F&"?>??GFD6"=9%#*/!%H+6.03BB@,3.>.%=>&=G=9@."A8C475$C%4/;/A3:-A.-G7'='7+,2;/5/"($5;0!<1C,=&D>7,,<8DC!*,>(@)@:(51"(,);35D2H*.1A:$D!3(86E*DE+,=6/C+
@r4956
TAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGNCGCAACGAAAG
+
<C/4(3=H587"/,1467D2><8#1%7"16E$2(2=-%&+,'6.D)E+B:;.4&E6H'*H*'?611A/-0E*5;/H.--"*H::?8"4?H$'D),,9(
@r4957
AAAATATTTTTTNAGGTCAGACACGGAAGTGGCCNTAAACTCCACC
+
<@=C?'-C9*"BH$@0>3>&2)<62:.5*$H/*@5B!:/*>4A-*?
@r4958
NNGGNTANNNGCNCNNAGNNNNNNNTNTNNCCCGNNNTTNTGATNNTANNNNNGNNCNNCCTNANNTNNTNGNANNTNCCNNCNNANGNNTCGTTTGGAGACCACTNNNNGTNNAGCGNGANNANNNTCGNACNNCNNCANCANNGANNTNNCGACNGNTANTN
+
!!#$!$#!#$"$!!""#"$!"#"$!!$!!!$##$""""!"!##$#""#"#!#"#!!##!$$$!$""!#$###"!$"$##$"$$$$$#"!!"#!##"!!$##$##"#""#$"$!$$"$"#$#""#!"!$#$#"#"!#$####$!"#$"""$$#"##!!!#!"$"#
@r4959
GGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGA
+
$.=1,:541,GBD"A'=7:96%/-(;!F64/--E:&)DH/$
@r4960
NTGATTANTGTTGNTNACNATGTCATANNGAGTCGGNTTGATAGATCCAGTAATGACCTCA
+
%##&!!!")!#&("&!)""#$&&"%%*!#(*$%&""(%+)())'&+&"#(!!$!'(())$%
@r4961
CTCGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGCCTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGT
+
)"9B9!?.(H<9&6+)/5#;$@??(!53&,61A"$@F/6>)6?AD'@"'0!D5F",1$B/@-!*9<3:+60?8".424&2*8?/7='AC$+)<$1&5);10DC'6=EF"-+;46:!<C8?.9)9':+<DC##C8'77.$$)5,#,;+!C#'E+1;E*)@58@*$3EF@*+/C%F@)C*3!&+--):0=2(/2)-!4.:6;G2$'3*&0F0">')#C%-*%+
@r4962
ATANTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGGATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTNAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAA
+
998A<AA94B.227-:C9!3$C9E6<E/@4.2/50".%H=!%/1EF8F;:%06*%6*:6=@<-D+77@/C#68D7'C8C-/7C0+-H%&*7)<23<:D"%/449*>?-E@#H!78HB@D&%7.D<$+,+,;G05&7!&7H74&!3A;C<>2A>H@5H8)#:>80,6&
@r4963
GCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTC
+
*?(.A0!D/G?7B(4@'+EHH6G%=5H'$1+0&<@0"216?9=2C%21!D@E%<2F:1'-<8;-A(?(E&06)D>3@.D,9C7<10E)2C3;6,;/6@C;=G(?#:F%64>
@r4964
CTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGGAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGANGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGNCCCGGACGCTGACGCTCGACCGTGAAATCAC
+
6-:2/>9"F$<:?DB,12"E8(;3H?)".7'DB/+#F<./6*!94%:#G*7!4;G+2!<E2B?$.&%=8%)BE,BE)?#$455(B8@$B0@5!E0/E.D);<;:E(5/$#?>?=:1>?"'@=E';"#>H3D<B57!)*;0-%GFBC!79B6?)?B5<D1/=9((3BE!3(
@r4965
GTGATGTCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGG
+
40D0@6E,*A3#CF+=46H7A+@%@E:*7>=:'>>FA(9(>+,3+-?$AH-A:7C:5(5E140EE5/*E)()6($8A8>#+-7#5.!"1+,4<#/"8H8C?'3<G
@r4966
GGNNAANGGNATNNCNCCGGNGCGGNCTGAATGGCTGGACCGCCTGACGCGGANGCGCCGCCACCAACAGNCCCGCCA
+
("!&&$#'$'*)!$)#)(&!!$)$$"%'+$("##!#!)#&(##()"(!!!%+&"*%*("(%'()%$"%+"*)&")%$*
@r4967
GGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTG
+
-@@78"!C49#@(-A1B6&#-0E86!*(4:,@)"A!843C.5!?'57,:0&;C14!>5G<BBF+'H%E/5()0
@r4968
AGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTNAGAACAGGCATGCGC
+
6%9*&5:1/424/?,;'>62.=@C72C0&80$@.,!&5H;9=/A-$(F+5G)1-G)#H#().-A.=#!=<;9@==E0";
@r4969
CNANGCCATTAACGCCTTACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACCTCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATT
+
("'")++(("!("&""(!%!)&$++&+%*'(+')&**#&'$&+&!!"#"*+*!+*$$*"%#"$'+%&&%"%#*%'!(!#"&+&%'*$)##&($*")*"$)!("*%('!*#+
@r4970
TTCGTGCCGTNGTTGCTAATCACAANATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGAT
+
A%1/!4<'0H)2H=E/$92$>12",F1%-&@/FC2/$4>CD5?&@<0F)505H?&>+.8.:.-!H3(-.<'#D,#"/9+51*&6@'(<1,(1<:)3F*A/2!27@6'F?"8B'/B#-/*7#(G7,++G+2G@A)*-
@r4971
NAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTAT
+
=H1GF01DG?&(-1.;>3!9?5)-%?;+E8(G;%FC.*G##.961D8!8G1*B@:HC+EB8C-1*9BH(7%9F%',<#H.)6@"-,=A,(!,68"<()7:0/*AD4:+9F
@r4972
GCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGA
+
@>2%63-+$E32B-!A800/DH70-'2H<0GD%F*#2.:2!4/G)B5=77G1"29;G:F2?3=?#8(<1D#.0::&!)"2050&%38C.21";&)A:!?%3D39
@r4973
TACGCCGTAAGGCCGCAGATGAGCTTGTNCATATGACTGCGAGAATTGACCGTGGTGAGGCGATCCCTGAACCAGTAAAAC
+
8*8(%B"D<='3E+'5'*0EH93<@&D/#:).6:G33A>)73"HE#"F,E!%0#((?/G,#F69A&D1+721":"":#@,G
@r4974
NTGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGNGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTAT
+
&E,-2A%;:6/,GC"HF<3-BF;(3@?&,)0$5*,09*/2A%-8)#)D.807)1E29)A$.#:5&2?C8F2$F,-;.;E&3'#4#.BG0)7E$6''1%@'+1$1'@+0;E(!=&?'FE%+9C@AGE=&532-$0.F5B??,(5G+49'!$;<&F@>94+CF>$:H$2"/!#>)EEH1%A9E$%B"CD"2C@!)=!1A@+1)."%1(3";'+;.-'G2B7=!F(A)5!#74+@!:>H32?1-
@r4975
CCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATTACTTCCGCATCCGGACGTTCNCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACANTCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATG
+
8':@+,'F=1:G=59*)+H9D(?&38?,:@**=:!!*5B/;:G!",B+7G"<<$--';AD&):%>?9H,-6B%;A$DC92@,D4.1'A>F-E;)6)>C>)''DB3'-'4.::@0?.6=&6"52E$H--C-9@>F6"(03.)%*C"DH71'@904,C>1<0AB00129!BG#@(E3;;48D/>0;D.C#H+<G$,!@B3G8:.*BC1
@r4976
NTNAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGNCTCCTGTTGATAGAT
+
$!#%(&+%*'+$"!'"%)++"%)$!()!&!&))$%!*%*"&)$($**#*+)$&$+##!*'%)$$%!
@r4977
GGNGAANATTNNCAAACGATCAGNNGCTGAAGTGATGGCAG
+
'*%&$&%"$%!')&%%)#!"%$*"+#*&&*+%&#)'(!(+(
@r4978
CAGGTCTCCAGCGTGCCCATGTTCTCGTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCGTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAA
+
6E="-E1!9(:2<FAD'*+F:731-?<;B#4F!8"2*>9.G!8)<ADFC>+2@>.8<9&A&C%8#76C2-%7BD!:?2"A:*?3D;B(!B8#&G115=-<9F.1>3<4C<D+5&:A9;1A",H3F8DB:D5G>
@r4979
CGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATNAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCANTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGG
+
(9%,&/>')B0:9*G/(1#(2CFH36/E4"35/:'+'6'<*G$*0&<G,"%6*4,&G78.-$+#%<-<4?''A+'3"FD.!C-?$@0=;;&5@3=.7.B$"!2$H+'@F-:+"-2*(/D(G*(2@1.116%'"E,1/+$&):G0-'EF<#G%.)-&)B%A9+C&,*"+F47G.93;-0F+"E"(!"*7=0">9&*H=
@r4980
TAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGT
+
6CA@8>05,%&%,8@:"@<@C-+;BBC&H91G3)1H;&08?;D"F
@r4981
AGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCNT
+
/?%2,$G.!FE>$:>B'=&-=#7+C(7/;1F'"$@$,1=A9G*A&B;#9.!9,H
@r4982
AGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGAC
+
>;+0:?8C#C&531%8;@/A&63>%/>$#>C=>&:87?5&.BC6*"5=BB%
@r4983
GCACATGCAGACGTAACCACTATNCGAATTGAAGAACTGAAAGAACACCAAGCCGCCNGATCGCGGTTTTT
+
+%"!%(*%"&))#"$)!&&&*%%*$#*'+&%'#%'*)+%+#+$"(&+&#)!$$'+#("))$!)$#!+*%#%
@r4984
CGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATNTGGTCGGAAGCG
+
'*4'/2-D4*.BEA?,@%4(2':.'@@G*D?#-+5*H?<4<G!&1%#==#%3/')$8,?;0.0G'*:1;0+BC-157?+((B>$=$*H--D,4:,G"*<#<G:,&#?C!/(2.D$CC,D8#10D049007B#AFC#0@A<<A<"*.;),<>26A?D*@(<!<;B-5
@r4985
NTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTA
+
'7!5+CDAB),D(&)9E1B!)AA.F+A4BB>.C7F:)0F-G:1-:6D%>#5.>%81*H
@r4986
AAGNCCNACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGNGGGGGAA
+
*$)"!)"+#)&$'#(&$'$&!#*#)(&&$%!(+)#("'*&&)%"*&+"("+!!!*"$&$!"#+!*!+)#&+"(!)!+&$"'%!#'(+%*$)%$+&+)(&!)$$!"+$+'*"!+(&+&!&)**#+#!'('('*%#!+#"%(#!%&&&"($"+$#*$("*'))&("("*+*"$#*&#%&+*++&%($&&*"!$'&')($&**%#!"!$&##*%#
@r4987
GACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTGTCCGGTGATGATGACGGANCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGAC
+
;19FF;D/14$EG-*$H,%@F%CA8AB0,?$'D;H"="/9@B,"E/D+12)H3+?;B/C?1B-@8(D++5'0/F+3"%<=5,@(404C9,(0?62#A+/3%&);B<5*,A<4?=$5"/;428!9&#6;350HB.2<)
@r4988
CTATGACTATCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGATTTACCAAATCCTACAATGCCGGTGAAAGGGGCCGG
+
%G+)@!D.G19#C"$%:.$8%?)&E3G7+)7F>C@9-<&B/,738*%+%.H<.23@&CD/#)H,FFF6!8C3E7F,28@*>7>E"56@)E<"!,0(FB?<3+C--%"")$0G$0,!<3@1>$.,1=5'2@B8$,&
@r4989
NGANAAGCNNNGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCGTGAAGGAACA
+
$$*#%%('#!&$+*(!*"+($"*#)$%!"&&%%'#($&"(##*')!#$#*%&*(+#&#&*$&"!+#)
@r4990
AGNTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCG
+
6*"A@"'(,#%)9G(GFC?!-1'!A4+D2-FF)D#@"B0,%==:E5BC/E
@r4991
GCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGC
+
<48F>-"!<#<72:+&"H<32;CF#G<F0BFD&78F3+G5
@r4992
GGGCANGTNCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGG
+
$%'&'#)!"#&++'!*)#&#%!)$'!)%$$$&)$%*#*'*$*!&%)'$*''&+$&**#+'()+"'(&"*$())'+)#!$#&'*)*$!*'(%(("*
@r4993
CCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTT
+
;,;G*G?/"/2A19<B./*/DE";?!2)7,H$52662-:$9
@r4994
TGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATAATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGANCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAG
+
>8"")C%(50,A.%1HHA2B+36F,";E1G>(,00!-A>94G1*!).%8@7;@+$!G3-A"%+#4)(D8"((6*5B6F=GH(-1!@&?!9(2D@F"30#?1E)'&5&+$6#E?=CH<%!81:*6C8&%6(-:10(;E>@4HA8?"4+9/A><B-C;71-3%8#';59@!>=445!1FH2@DA5??9A291);EH',?33'!/3.;G+.<1.H)))#,D?"'D8)'99@+5$1E@&H@/(>E:>?8EDF$B2C(+;CAD!2!+*
@r4995
NNCNNGACCANNANAANTNNAANTGGNNGTAGNNNNTNNNNANNANNNATCNGCNNGN
+
$!!$!$"$"##!"#""!!"#$$""$$!$"$#$""##$!"#!!!!!"#$!$""##$!#"
@r4996
GGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTN
+
+(*)!#())+&%(+'"#)#$(+*)+"%$+')#"&"##+'&+'!+!#*'%!(#'*)&#'+!)$%*)*%)##
@r4997
ATGTGGTTACATCAAAACAATTCCCATACATTAGTGNGTTGATTGAGCTTGGTGTGTTGAACTAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCANCTATGATCCATATAATATTGAGACACAGCCAAGNCCAATGTCTAAGTAACTAGATAAGAGGAATCGATTTTC
+
<3D"/',-H+)$$22H)>=@08C*,"5,7'5C;/0-0/1,%/8)F.03A,'%G05>:.:E"G#%=2.#GE(-77,=3CD1@?CH#-HBH%1+:@90?66!E<=(9"H#3A/HB7.2-4?@A$F1+G"00*</G/!B-F<!/?#"23;=C&*HHBE)=8.GCA;3F>5,D4.75C412E=DA1G3(7'C*'2@>'95>44G!,A-H2+E8E7
@r4998
AAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCT
+
@&</*=/5@*%<F1!B,52?C<C4.;7ED!%E1+=%2&4-A1H/;>+E;0
@r4999
ACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTNACCCAGCCACG
+
/!-C+-:3$44@-!:"!G#'>9//.:H.F'&@9&E"$/1%)4-E%A2
@r5000
GCCATCACCAAAGCGCACCTTTCTNACAGAAGGGACCGAAGCCACATCCATACCGGGT
+
G'>FD?.4>$2#&$2""1*89*,/&E<@&0*:750B(,>$3%(#$GA2??-A2)(G;9
@r5001
NGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCAC
+
"G."9,./6:%3!"?1;03'&<<'C@"-C?.5C.7A1,=HH:'/+H161)
@r5002
GNACCACATCAGGCTCGGTGGTTCTCGTGTACCNCTACAGCGAGAAATCGGATAAACTATTACAANCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATA
+
#&+%(!#$(*)#$)$&"""&'#!#+!+"$($#'++'#'#*"+&&)#)'&'!*%!)*!*!!!*&+(&+#($(&#)$!&&'*#)$*'(!()&"+!'()*'$*)'+$++&*&%&!%#"#&$$&)#'(&')'+**")(((#'!(+*"(%""!($%&"'#
@r5003
ATACAATGACGATACNTCGCACCTGACATACATTAATAAATATTAAGAATATGAAATTTC
+
7(4F78=H/,-)>=)*9(38-D"=<3)EA8'//:@6F=C-/.<'.97$0:>$&:=<0D)"
@r5004
CTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCA
+
+++#!)&%*''&+#%((!!(&*+$)*(')(#(#&#*##*#%*%%&()%#')%""*&+!'*%)$$%%'()+)##+!+)"&)!&'!%)%)+&
@r5005
CTGCTTGATTCCTCTGNTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTTAGAGGCTTGTGTTTGTGTCCTGAAAATAACTGAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAAC
+
%C+/8;"D=$D>2>%=;0)-5%94/698/D<&3/0:A9@6.:%2*9G=2)'G-%B"%<.=H=*/&!E40H1B'A:!;@G(#;G.?5&(#964#-@9<B:/$'9>$A"B)35?9!1((&+C>C9F$&2,@".5;$1&==3B-6&##.D,?5+2".?:@7()9>)!&>7/;4<9#("*<,CA#
@r5006
NAGAGCTCTTCATCATTTCAAGCTATTGAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTNCAGTCAGA
+
"D>)E>=)4H%D7C&$$;3'"1;:5*$1?#:+?A;74B;>(4DBHHE;,D<E;8;2+)?"%=-',/2FBE)3?$F:G/B)3'1$,$8-80H.B6;E*7.!*5=AB7/H77/DADGH-A51E+<!B582)E9<3243??5*@%%&!0%#%1?.+!50
@r5007
NGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGACGCCATCAAACCACGNCAAATAATCAATTATGACGCAGGTATCGTATCAATTGATC
+
!0D*FE66GH-F8@H(,<-;&#4#A!&8%'&)?*",%&+%>@>12)"EB4A34*9!6:$HB3EG>,%C8'BG.".;@"""&0A=>B>EB,4/"-E3-(+75(
@r5008
ANNAATNGCAACTAATTCAGTCCAGTGAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCANCGGGAAAAAGTTTTGTTCAAC
+
'!'%!$!+%%))!#&'+(!*&$*%%#(*'"+)))*+(#$%)!#("*')!)&&!+*+&"'(%!$(!"&+!&%)!%&&!"''#(*$($$*
@r5009
TCCTGGGNGTCTCCTGTTATCAANCACTGCACTGNTGACCTGGAAGA
+
'(&'+*'"""($))(*&+$'*%(%###'*&'+#($'"'***&(##&)
@r5010
CNCNATNNATNACGACGGNCGCTGCCGGNTTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCNCTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTGCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTG
+
"!"%&&#%""&#%)($)#&%'%*+&!+()(!$$*$$(*)++(+&%"*#*%*($'('%%+*"*'!)#"+))+'&%&)(%)"%"*"""$+#'!)*)*#"'!#%*#")"+"%$$%#"'!()"!%*"'!$'%%*$"!$!#!#(%&")&&""$("&%&*#%&("'(!")#&)#&$"$!'+))))&*(")+")&')$&)+$"&("*$)
@r5011
CNNNATCAGAAATTGAAGAATTACCAGCGCAACACAGCAATAAAAACGCGNCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGG
+
&$"#"&(+$(%*&"$!!*+*)%*('")#))%'&!##%*!&+!$%$"(%!'+**++%%+'(*#)$')+#*&')#%##('(+'))")$!+"+**'!$#)!
@r5012
ATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACAT
+
@#?(@5.*&?0-5$=.='-:,@CDF<+/.>-1?%*5(E<ABG!-)?$E-,;5'$?8(-1DF=$0&=:05/0!:G04H,,DG#,7E2'#D9G73+'G
@r5013
NNANNCGGNNNTTNATCTTACACNCNGNNGGNAGNNNNGNCTANNANTCNGCCTNNTNNCNNNNNNTNNTNNTNNNNNGGTNCGNCTNCTTNNAGATCANTNNNNNNTNNNNNNGNNCTGTNCTTCNNCGNCGAN
+
$!$#"#!$!!!#""$#"##$#"#!!!!!""$!"$!!#"$!!#$""##!#$$$$$!!"!!#""$#"#!!##"!##!##""#"!""#"##!#$!#"$$$$"!$#!!"!##$$!!#!$""$""$"!$"#$##$#$#"#
@r5014
TGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGNAAATCAAACGCGCACTACTGGCTGG
+
,6E5E<!06HG-"*:?4>G:C59%.,(;2D6,=-1;9D0+9%*-E-'81>)+BD#.%CBG$%HD6!&;+:A/#%G)?(9!.>H4!)-1474*(BC@+"DF-703"58!"+#>E>7712:)!#H").:A/')3DA3?3#"C#%B$,#09+
@r5015
ATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGACACANTTGAT
+
8E748,71,8.B=59"H(:AF0;4C+0$?/B37%<-<H=75ED4(H')@?;>9=BC$
@r5016
GGTTTGCCAGAATTGTCAGATTTCCACTTTTTATTTAATAGAACAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTG
+
%0!C;D9#H7+!<=C71(6:$43AH,6#!/7:*1A>2'=-0/@@#+.-@49:6$$+8H-!&"C,7>61E;,DG$H(,8,FH*
@r5017
NTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCN
+
%%&(++!(*&*&#+)("*"'$"#**!'!+(&('+%%"(+)"*&")*(*!(&)*&*!$&**#)"+#$)!&"+$$($$%$
@r5018
CGTGNACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTG
+
+"+&'""+!""(("%%()##"&+#'!'*""$)&!''!$!")#
@r5019
CGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCNTGTTCGACCCGAAAGGCTGGGCGCTGTTCCGTTCCT
+
5D/88FG62+."C1&*">*DBF!D#6E86(65C8/9@%05:,E<,@5C).@1;0'-+)E4-=GA<8";6++1,C$5H-)299)4(0A()9>6><"B$1>0E*
@r5020
NGACANNNCCNNCNCTNCNGCTNTNNNNNNTNTNGANNATTNTNNCNNAGNTNTNGNAGGNTNNGTANNNTCTNNNNAGNNNNANGGGNGTNTNNCNGTANGANNTNN
+
!!""!!#!"#$#$!$$""$#!#!!#!$!$#"!$!#!"!##$##"!$!!!"!!"!"$#$"#!"#"$#$!"#"##!##$"$$!!!!"$"!$#$!$"#$#!!$!$$"""!!
@r5021
CATTCCCGTCAGGGCCAAAGCGGACACCTCCGGCAAGCCC
+
042)$18>$F@(>*<4,/7&(058=::F89,!H639:&+-
@r5022
GANAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCA
+
-65;1,%39&02+>B6!H.;/):<&G((E-/85!!B9@!A=;5!A.85>G1C<&@-
@r5023
ACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGG
+
9BA8+,C,D7$D%)"F5+8E::<:'?A;9.04$"B456G?#=C'B$.G-5?8/2,"="@48-8)G'.@F%<9>D$%B==--3.*7%F4@GFE:#683(#8F2E<%+61F5,1.;>6=.+66()>8#$;7!.@B3/764EBB'5>*
@r5024
TTGTCGGGAGTATCGGCAGCGCCATTGGCGGGNCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTT
+
4&6%:7H$=0-5'&E#+7H*'/G=!?#&H%),=&FG,<(%D>A"75)1<+.5)%&B$E79C%%9<@'9B3D=D0#$"8(&B60EH>'4H1)BA>0@;@2.#-8/(+<2,FCH>7'*.2'**--D',B3=6B?H/@A0(:-$/,B1*5?G*!@50<
@r5025
ACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATNCGGCCTTTCNGGCATTCACNGTCTAAATCTTTTAGCACTTGATCGAATATTTCTTTAAAA
+
(,9;C9*1+!!817/<B=D)(6:@#>@0<HA7'D746D33<&22'<3C+)0DD!4'A-,"1),=3G:%-?3E6;'AF!=&(F@*23F,C&F'B.<GD9@=E&40#CH./*9(DG@D>D1<<!1(5&<CC@E,"8+>!6#E!98G+B$-2
@r5026
GACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGNCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTNTTTCCGTGAGAGCTATCCCTTCAC
+
@#3D#*3/!;C@9#'19@,<@!3F.'3;GE(A7?5"9B8DF.-BF&?'@)/5/3A:2*.>-7<&BFB')5)<;1.06?$.(22A8F9'D;AF@>$*83C0?@>-CFE?*=!?B2B>?33(5F&,20!1A34B@F2*('=0H>D<#-3?(::>B:"@D>F:*.65B<>6D%28H?8.0;62#">!&7$-EA00<+(.F8H93:#C@9><
@r5027
NGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGAGCTCTCACC
+
&%&)+$(#**+(%'$#")#&)!*"!(()')(!+%+*)$%+%"$*&!'!'$)"
@r5028
GAACACCTTGCCGATCAGCCAAAGGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTA
+
/<D2B%-1B"#&647D?176?70<G2+EG=#,*&$+)D0"8@C'GB'/A8/10;;H7>D(*-0304#"G8981B0*,BF&6#?D./5H%8A3-*5?$6%E
@r5029
GTGTTTCAGGANGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGNCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAAT
+
%$$""*'+("!#%*'!#'#"!+'(#$*%"'+$%+!"+#('"'##)+(++"#+"%!!($%*##!($$##%$$+*$"(!*$%")'*&(&)'#!)&"$%**
@r5030
CATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGG
+
0;%H,6%A">F1(E?B637++-56BC+;;2A6$%105B(#@)0
@r5031
CTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCNACTGCTTAATGACATTCCTTTCCCGA
+
@H4.8#%1D%526H2E?'"161%C#,629=!6?<+2#8.*/&).:F1;3;F5@#E@@GH@A&&!-=3&*D//FD#E41G>0?36G5838,31*B.6?98='#H&85B9*D&&<4E>"H//
@r5032
TNTAGCNNATANCNNAANCAGAACCGGATCACCAAATGNGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACNC
+
&(!"$'''%'&&%!$%)!$(++&*&'+#!&'$"+((()!)+#&(#!*"+&!*'!%((&#)%&!)!*#'(%"!)#*'%(%+%))##!#&!#'*+#!"'""!#'&#(&+'"*&%+$+"#%)!#(#&&+%+"!&$)'&#%!##"+
@r5033
NCNAGNCGCCGNNNTATTTAANAGGTGAGAAAATTAACTGCTTAACT
+
")&('!!%*!&("#&*)($%*$"+)"'&%#"*"$$()""$'#)(""*
@r5034
ATNNGANNTANNNCATTCNNNANACATAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGG
+
")!!%%'!$(#"#$(**&$%$'"(*)$+!()#$$#&$)!$*&##*+!$#*#))$!!)&$*%%#(*'*&))(*#!&!&#)$'##+$!(%*&$%"$&)&&)%""&%(!%*'&&%+!)(&&"%)$*"&()*(&!+$"!'%"#'#$+)&!!!&!*'()(#&)'+"$'#(%$#+'$%#!&
@r5035
AGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATNCAGGCCAACATTGAGTTATTTTCAGGANACAAACACAAGCCTCTGNCAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGA
+
.!@E&G*21;2*$<!?B/(E9A@=$%?!@.+52;9BB:4:?7+=76G0$G.$)A4.3B=.C'!02))=:@+7>53CC9$CH7(H33$G;GF2"&2<;&#F#A;D/8;*.'/.+;&A;D24"($&5;5278)=DE@;-5)1(C4?7.D!#<A$2E!3E>A#9,2F
@r5036
TAACTTCCGGAGCCACACCGGTGCAAACCTGAGCAAGCAGCGTGTGGAAGTAGGA
+
D+;"-$"*1&;A4%25?<GA'F4(7/G6#A=8:8,89&@?F$@1,!"H1D&19C=
@r5037
TAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCAGCCTCTTTNCATCTCACTACCACAACGA
+
H/@'-5;=<)#'+D?FBB:?3DC7,$@(2E@D4;"C2?2.*)->16/(8;*3+"3*>0(%%>.E)+@0-@F/-3(&4B+DHA5FE*/&G#C!C:*G#>1F+)%>FD<5H-3@!+#,1/-E$'C)'&4%2E81FF:686E$B97&5E
@r5038
GCGNNTACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGA
+
&*!*!"+'+"%*"+#%#)"%#%**("#!+&$(&&&("$#!&+$+)#$(('#(*!&*(%'*%"!#+(&!
@r5039
NCNGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAAT
+
#$+'(*%**!(!*!(''"#(+#$!'!''$!$("!$)#$%(#))"$&#$"$(%*%#&$+&*!&'"$
@r5040
TGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCA
+
4B4*<2<;E/)>06+D:+:/$0.61H'.!4G#48A/H&7>1B8#.3<4?<<58B(2+25%60=HD.(*;,?:,5E+;=&:H5G67=8G'F/:9-99%4';$-!6-)#<A(1-A7&1A
@r5041
NNCGGAGNNGGANCNGNNNTTTNNGNGNNGNNGNGANNGNNNANAANNNGNTCNNCNNCNCNGNNGNNGCTGNT
+
$#$#!!"!!"#!!#"#"!!$$"#$$!!!"$!"$###"#!$"""$""!$!#$""!!$!$"!##$"!!!!"!!!$!
@r5042
NNAACGNAAGAGCNAGAAAGACTGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTAT
+
!#'"(*('&'%*())!'+$!('+"#'"**&(''+*+!!%+'!%#"(+$!!&+)'&)*&'(($)')"*!'$!
@r5043
GACGCCTGCGACCGGCTGGCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACTCCAATCCGGCTTGTTGCCTCCTTCGNGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGATCCCGTAAATCCTCCGGTTGCAAA
+
DC/8727;9&0@!&:3.&C&H'?;8B!%&4ED1EH2D1F<-B79.=9H)97%@#:(9)H!+F6%=%H:/9-#*9@FF:78"<B#A+&H=(!(:(@2?9/;/70"+=3F17"'E"()F8%&76;E2=@16$1+:'3?73+BC?%5!<9&%"2FC%,!@(-%%%'G5D40$(,?0#F-A84+*H//C<$C,95C&17G;
@r5044
CCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAGGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAANCNCG
+
:+*;03%+36:7>(<:<.02/9!!;37(AC;2?.172BA#/3HH'7E(<824*+E%8#G"-2//).13-.38#:<;E?"/<:#:-B?$?%7!2:$,;:(6'
@r5045
GAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTNCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCGTACAATGACGTCATAACGATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCT
+
D&%?=@'BB'67;#,+E7EBE-*/BBF%!/,#0#3,95@8DG8E6((><9=/7&:15*D).$-99=-"$F,D()6122B"&%;!<F-7:)#&8(89&4E3*/-.:+1D6GH;00!-,+.1;&1&$BH(A)?#HEF-C")(?3209F1,%3C56"(@@
@r5046
GGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAG
+
*871AE*651&F)-9@44,>(@=*484H9ADH4*ACAD.0F,%GH:*H/;%7CF1'=(&(DH>1<B-&
@r5047
CGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACNAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGNTACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGG
+
,9DC98)80$(";&753<B0A)-=9"E9C1C(+C@))1;:H,#=6,.E%-39,H<"B)9/:<=,E*8498,8,,4'B;)<.&<>.>'<,.B38B*D9>-"++B?&B%,%"A=54.?1DG&3"D#/?64G235CG,)%0>#-2"7'@7G*1E-<HA5?9.D/5%@A#<*9!1*,H;886@81C(A-?'):'.;:"-73:.1";,,5E">A"C'>F<A:&/HCE7,:F<<$EE0G).-+>@1<8EH;!)EE49:0$2=69*9:F4%2AD2!/C5G:4E:&0B<;5,84#014+G'!?C+F#*+58CE).68"/"2G!D4"HC/=;*G0(A4EC/C#EG:2/;(7-&::+-*1+EE2.,:7%-8E2047@;'-/!-">-C.>D?3#!!+<*:F":(;:A6C
@r5048
NNAAGGCAGAGAAATCACGGGTCCGTGGCTGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGA
+
)!+"#$%#+("%%&##'&($%'$%#%'&!%*%&&!)'"')%&(+$'($(%!&!(##'$"*&*'"!!%*+'##*$$$(%)%!(&#!!*((*%)+')("&"&"+)%""#&#%#"(*%#)
@r5049
GTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACNAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCG
+
.1H..'<C?H83:$'2AA3!#"G5;E")A.5GF6%483E6C5-B:AFHD<9=0.9.8G"!,!2:3H6"")"5F.7%;@<3/)$141-5CF%7!9D/'&$1&;
@r5050
NAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCC
+
#%/'#=7(A2)8"$CH,>>9:4-#'!E5G#:!0D%=@,>8+(9:-G)0(0/2D18F.';5%6&)H'>4,$"AH+H-9!"H.'&//)"2BD&/9)DE00+(238$'E)(G0C<'!@01C>@A*;F/D!'F
@r5051
TANCAATTTCANGCGACTTAAATGCATATGGTGTTATGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATAT
+
*()='A5A<H<9>/@;#EAG4>E/B5:&4*,"!FH='7C'?&HD@;'E'/F4>2E(-123B?,,14BH0E1(<2!=:5#D,.-+$@,85FE1#@$C&*+BF*3.:#+'!70(7:@%),69(
@r5052
AAAGAAGTGGCCTGACATGAAAATGTCCTNCTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGANTGTTACT
+
5D=92);=F$2E,A5G.67=<"ECA7F5.(<57<)H=HC=)8F--G9G&,H1$;BH(=<1(H?B&0+F0E<&6D40BEB'B#98.E7/82E#0,H!F.F.2+1E6"97+*++-8*'6?$741>7<298,0HB;/44122A?A/@2/A-'-D5(;(7E7'2+<2
@r5053
GCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGNGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGT
+
"-!/"/DD&<F2(7A=6$*G6<,)5">7&4;A61.#"FB1&7.5GH#?'8B7=/8%3#5@CDD5>=">7AG"(@,4.<6A
@r5054
TGTTGGCGATCCGACGCATCTGCTCACGGTCCAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCGGTGTTTGTCAGGTCGAGTTTTGGTNTGCTGGCTGTCACGCCTGCCTGTTG
+
&$%"+#()$'$($&((*%*%!"&$)(!&)!'"%!*&#)!)%($)""$$"&&%&*&"!&)&)("**%%#+#$'&()*)"&&+)'$"$%$+)$*#)$&!((%%*!$*&)*)(*'&$*'"+((%!+!#*+!#*&&($%%*#
@r5055
CTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCCCCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCNCATAAAGTACGCCCACGAC
+
>5"<AC,-.3,=4435&HDE#)*.;6A*<%-+9EE::&F"-;27DA?,6:B;HF%F+76!+/%#:$>=-!,+F)H7-E*97$;5/50&+%F"%%>!*=?1<$E"=776-.('H!'+&#%H650,C(F#=!%HC6
@r5056
TGAGTCTGGATGCGGCCAGATTTNACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCT
+
05>,(D:&)05?4?CF<+''9A(6#?D<A25G1H8F(&;7A5(,++)B:4A&B(5-2B)
@r5057
TTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCG
+
B?G08C",>CA7>8!*<:F2A<$27?$@/3)'9BE8DF<,4.H>!8!>E,=*>)%49'9#=C";5G5<C7/00$;-*1
@r5058
AGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTNCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCNATCAGTAATTCAAAACCTTACAGAAGAGCAANCTAT
+
+$'%)#)"!%(#)()*%'##%"#+&)'#(!"+%"$'##!!"%$(%&"!%""%"+%&*$!()&"(+!#&&$#&""+')!#($"!'%$!#&%)*"!%"($!)"*+&)#!$!#+!)#*'"***+$'(*+&*'*(#++**!"+*)"+!$*''&&"+"&!)*"!+)%*'+!$**)'+))''#!*)")&'&&)!
@r5059
CGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCAT
+
GA#D1DE":C7A5D0")(?130C16.)*E"//"*0-@6$5')3="C"
@r5060
CGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGAAACCGCAAGAATGCCAA
+
HF/E1$%.8!<@98$:F4D/-(+E&'27?A21C=E*DA.D,)@2*7::!&*!1C*2=>H22/B6D@3-5>.3A6<312,3,C)0B.A32()2H8406/*1,4#$<
@r5061
TCGCCACACTCACNACAATGAGTGGCAGATATANCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAAT
+
)(%)*'*(($!(!"+&+(%%())!#"&$"")##)$!*"#+!($'#&**(&(()&(%($#*!##)"$$!&'++"%!%)#'*(+'&!)")&%%%*$&!%#(%#!"')$!(
@r5062
AGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTAANTTGCATACATTC
+
?%6*<A2#?!D0-5F/H7(2>$7+&3?A0D:;<(E0<@*'7="#HB3C4+$%51=@";$)!+6/
@r5063
ATGGNNNAGCGTCCTGACTTTTCGGAGANAAGTCTTTCAGGCCAAGCTGGTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAG
+
%)'"&$!++%()!'"+'&%%(&&+(+#&*(%""'*!"(+!&%*%&(%)(&'&*(()'$+&$(*!+"'!(*)''!*"#%)#%"&#+%"&"*&#!))"%$!*%)%#!)#***'%
@r5064
CGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCNTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCNGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTA
+
2AH,;6?+'1F58CEB?>&D1#56B/D)5)@AA6F>)!1,=4:5D!&4=;#B+@%(#*8-BG@1&&)A#4(')3&+00GA#/5"(/<0'5/A3H"<?:@4:A<24FA-A4C8"'28A+;;,*:+>31+3,.621!A5A-6)'612#:<,D,/C,.$(1@!;9&;=1=--="$8A(,#6&3>E+*3"+D0>FFE9<%9%*
@r5065
TTCTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTCATTAAAATAACCGCAATTTATTTGGAGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGT
+
"$$A35@BF!>H#>FB04C5-)@/'26EG=$++.<7/C//F;6G=E/G6!?7GB%G!*(#*-36=!2/E)4%&>)=/1):!F%B<@ACG8<9D:GE86()!A:E<<D3*H6B:?+:='#.!#6!(#/+,E=)-C"CE8,&0+C6-/=@4H:B')9312&*5&D<
@r5066
GAGAACTGAAGCTGGCGAACGCGGCAANTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGNTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCC
+
5D;'.4/:>@"+7!&/)!<B%:)1%<"H1F1'G6H!A00/>,3HC0>?8#(.(#5)<,06F!>3?)/&286C3B/0B@F,:;C+)CD*!:6<,ED2,5?/(G+=*"=(E*HF/#*&A>(54*8@B7FBH$<,!*F#($1;)5#)B;&'/*0+<(8@-(2@G::52?H#D#F8<>G!9#*8/G6?2+?'<5>
@r5067
GNNTNNTTTATGCGCTGGCGGCGCTGCGCATNAGTATTTCCCGCTGGCAGCTGG
+
$"&(*!*%!()!+'+'%+*$"$&!#%&)(++$)!((+'((#'%&')&"!)"'#%
@r5068
GAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCNTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGNATTTGTTATTTTGGCTCT
+
F?B;.ACEH0>>9%G#'(@%93&G%!D:!2-8HG"H(H4F.<%%.+5G*61:;D,F:==,EDAH.F6*B0E!3GE/<=)B?C?E(4*D>+3?)90G0;9>'C(D97*.GE.;89A&BH
@r5069
CATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGAC
+
,>C6%"-3-AF08(;20*%;*$#7BA,B'(A'>63&0D/%.GE
@r5070
CTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGC
+
B0/2?&)6<00#=E-.0;=*,B=+#D3%FH;G4F(@3:+(4E>0:&7'0
@r5071
TGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTGGTGCAGA
+
94>$<EH8=%9B2)C(@?A9B/1-D(B;!3;C@9A"!AH6?.6FF*=(")=G91?'#F'#B,2+3?G.G=',2CG82,2?+C1?"%DA/:<8?7&;E@F&1G.69?!%AE.DF%*F,B7
@r5072
CAGGGCNNNAANTNCTTNNAGNNCNAAAANTNNANTACCGCNTCTTGCNNTTNNCGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATA
+
$&&*'%##!#)"$#%'($"#!!!)!"%(*'#&)$%**""&)&'$(!'#"%&&#""!+%()"$"(!*''&$)"*"($!$&&'%)$"*+++(*%"+$+#+&+)&%#&'!''#&#!*$*$)(*'"'+%(%)*+''#(%
@r5073
AATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTC
+
F2!*&8-2B9C>6C.F+<62$/5@8(%(!""(??+(DD'CA4:6655,#50#5,#?)#:?:/@54>2>9+'/:8:#)<-*&<A!0FC$$'!(3
@r5074
NNANNAGCNNNCTGACGTTTGGCAGTCCGGCGGTNACGGATGCTTCTTCCCGGCGCCATGCNACAAACTGCCCGAGTGATGGCAGAAATGGTCTATTCTGCCGACGCGCTACGCGCATTCCTACGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGACGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGANAGTTGCCAGTAACTGGCT
+
'"'$!$()%&$#)+*&*$)#!+%#'*%%%#"%(+)(+&&!$'"+"*##!"')'*)('!!+!*%&$'$"'"+&+&)!")!$$&*)*+(!***)"$##+%#+"*$%$''!!$)"((+&)"&$%!$*%$%*%))+#+''#)'*%+'#(*#"+%#+(*''+#**!+*#%#'%"#(!')'"""#%*!)($!+!%&&+%"!'()"(&$$))!%*)%"(+"&&(&&"&)"*&#&(*(!)!&'%($!*%!%(!#%%+&
@r5075
TTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTC
+
(G(4)A%!AA%50+!&D%!-&%183A"C+)B$-"#%;?(,>52!>GH7(DD+43<G3A817G2F-/=@A%/%!8(2#-?%1C,/?0#)1+:GD>5;<1C5@F6=--)B),(FC?7<,'5.6C6*%67%="77*060=8(
@r5076
ATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAA
+
BGE?E67+?FH"C=",;E'9@'$@.5:3((2%D(*B=<-CG#,>3F7A#,0<@G11D><4=G,98&.#
@r5077
CGTTNGCCACGCNAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATTGACGTTTTTATCCGGAAAC
+
%&!)!('('!#%"&++$#)*%"("*''&%)**"#&!***)*$$&&)%&&$&&#('#(&%'%&)($%)%*'"'(%(+))$#)!('+#''%))(''(*'")$%($$&"!
@r5078
CANCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATGAGAAACGAACGCATCATCAAGTGCCGGTCG
+
31.%<2%7.:->',08:9=>:B>38&D)B)5&A8,<+?='3@?>F99+)9<-;?7*,!CC0&A;D/0H?+>;)
@r5079
CGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCNGGC
+
6)',"FB!;+2(H%--!&$$+,$29C=F%9,A0*B)$B&#-A=<8$$>772)D>19-!*6077
@r5080
AGCGGANTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATANTTCCTGGCTGGAGATCTG
+
1D&"(,%(*6-0;:&99@=;@4:4EB#!(73B&'18!-7,5>9=%-'..,&-4:1%,9F8&20#*$51,:!1'5B278:&.7<"@/G<7F"/-#/
@r5081
TATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATNACAATTTGCTTATGGAGTTATCTTTTAATTTTAA
+
,H<G/<%!$.1GD5+"A@.-"60289H(7GCGG:5?B"9&3D39:.3A/%7$H=>=A"#(%4$.=H$D&":-;C'@F)@
@r5082
CACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTC
+
G32#D#G1')E/'5H=&/>>(4(>'-D2!1.*3:/0DF1!?C$"?+#G
@r5083
AACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTTACTAATTTACTATATGGTTTCTGATAAGAATCATTGCNA
+
$-2=:;<#09@7FG8H,=0C2&E76F8'HGCD"<,&'*8E$EFF2+A(A)9#B?#*3.'E(E$B);*251E-B"".>C/*9D$H4+18C8)#E++)
@r5084
GAAGGGCAGCATTCAAAGCAGAAGGCTNTGGGGTGTGTGATACGAAACGAAGCATTGGCCG
+
715?0B:.(E3><)&;<;":@.!"0=2*5&A&01#8&4+=2FF-&6A;5;&E"-&7G@:'@
@r5085
GTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTC
+
8<FH4B(!=:3@(E-$>-@2*:C?>.@-!E;H8?9,E-@%E(!H.;.:"D'%?(F
@r5086
CTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATG
+
#4$;$GF(>301G2BC4&<G&?*@%+($+8.3C$C6(<!914/GE*+301&:5A",1H0@1@-)-3)<G"E;:)
@r5087
CCCATCTTCCATTACAGGAAACATTTCTTCAGGCTGAACCATGCATTCCGATTGCAGCTTGNATCCATTGCATCGCTT
+
**@9E<097*2/2"1&/ED596?AF7B"0;,H@#)"-7HB-%3C,.&(5B01.=37=?8?-&4;/B!6E-).-.>-41
@r5088
TGTTTATTTGTAAGTCNTTANTGCCTTCGAGCTGTGCGTCCGCATCCTGAAT
+
07(>"E:(2GA=0$8"9>$:%!$<;A5(H-65B4</A<3+39=F1*E.B"<'
@r5089
AGCAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGANCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCG
+
*%!$(+()&"##($!'$&)$*&"('&$*(!+"'"")("$&#"*&$#+%+()%"""")*+&+&%"%!#&'(&**$$'*%+!+#!$*!(('!$+"#($(!!(&(%("'#%"!'&")$"$*$#!#!+"$!$"!%*%&#"%&!&"(&%*$&)%"*(*+!"%('#)$$'!"'*)!%'$&'
@r5090
CGCTATTTCGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTNCACGGATNCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTG
+
*3.E%>C7>;."#/*&0;-6/F>:"@H@"H.?29'D46C-G?>?.9>84C3%!2!&8!1*61$1.,+E02+,30=*09;'"C@-/:*:(:3"!2/9.>++?2C;GE=;;))<A,"58-'@3/=2>C="6=%?G%3)<'7"03#*<%-7;2)F4-6-8%D"!56@"+)?:7/,H3($,:(@GAEG""2F8.:75+3FC<(A/&43$$$)E=3D;6=$%(82604D)":5>6B-@EA@9E#@F
@r5091
NTGCGTNCGGAAGCGGTTATCTTTTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACA
+
#$$(#$!*+(')%$*&"")*%$&")&&"!'$'+(&#"$$!*"''"&$)##$(%#!($+&*!&'+)'+%#&"&'(!&++)%'+%+)&$*(*')&))"*%$*+%&*#$&+(+""+'"#(#!
@r5092
ATGAACGGTGCGGNGATTTATGATGGCGCGGCGAACGAGGCGGTACA
+
7'80/4B#0HFB#E$GG?3%:D$0-4.EH"/=CBA",E01*:DA*<,
@r5093
TATGATGANAGATAGAAAGTTACGACGCGTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAG
+
=B93<=0!F:,>H=.DFG@8)9662<:!1@EH&<!&H:99@";&0#%<#;,A5B-4=/,&$1)(5H=C*?91A$,A-$H0!C6=""&8);*F?/H$&,/=<+>&'()1G30A<8-.4>A/.%5-*E<5
@r5094
GTGATGACAGAGGCAGGGAGTTGGACAAAATNGAAATCNAATAATGATTTTATTTTGACTGATAGTGAC
+
+)4HD)=$?/.H%+C!;,D"',E()3;"=7$&5:->+:?734F5(37:&C6.)>-8"F'%3<G33HAF?
@r5095
GTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTC
+
;A0/0EA+-5-=01"=F1F#<3@?(--D;2(2@)7F6BB=B<6*38%5=9GF:68D:AA4@!*F./B!1196!!7?("154*>.6:$"/;C<%EE"$H=1.CF3709@23(?$G!EH3.3/8':,38*4(@CFD<"5=*!3(-3H?6D#!<9-D#6+*)#'B/-58%)H3.%;'
@r5096
ANGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGC
+
?'G26-1*@A7')A*#C&1>83AGF545;>G/?!)E+A8'6A>)C?!>E@<$4,+@,6-?1,1E:?A
@r5097
GATCGCCCCCAAAACACATAACCANTTGTATTTATTGAAAAATAAATAGATACAACTCNC
+
;.8*(E,">/2":%;&DF"EC"D:A?@,'?1H,7*&A@-06@39$@4>0BGF16*5C-&+
@r5098
CGGGATGGCGNAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTT
+
$(,AH41<'5A!//E6";#F6#;'<%!BB$E94:6CE-:#,GF,*3"-=<AAF8E8C/,%'042$G89/44$.A(<#",."1'GD$%
@r5099
AAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCG
+
38"?2*91:C@2.="2+!.6?$G--5*#@E:(DF!$=7,(C=CB)4FG5595"(+:D,=A&>F4>=G2F+#0"$*%5?$
@r5100
GCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTNAAGTTTGATCCGCTGTTTCTGCGTCTCT
+
./F@&%29":/#38)5@E7)2!/CCG#*-+H=;:C#"29":-.G%H*E*!*+&!32;*4"7G$B*'E%E$-:;6<31./A3.+$-$H*?9,&6&0E/<?"9
@r5101
ATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATANTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACNGCATGTTATGCCGNGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAG
+
GFE''&'0&>+7,3F<7&)!*D2=1E'?&H7=69%3H%;G#64G<,G!&:E(0,!/"0)2&'@(%A#?==-6++#(F&5$@@$/$51(0H7=<4/5?/>"*+;)H0F.;F,%7(F'31C.'HD7-@:76?4@A$H<%>E<D5C2=>0.3?/6#4:F'!)!<*7C'A*?:978.,'/2'H,))F;$G?C<%0.H.:-(6B0D/H5-"H$H)GC0/&-0%<7)9C7@14DG1E/#,';*
@r5102
GGTTGTGTACATCGACATAAAAAAATCCCGTAAACAAAGCCGCA
+
0%0F;8@:0#"G)F'DB)()+.*1G09D8.2!3G@9@82#,G><
@r5103
TNACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCNTGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTAGGATACCAGTTCGTCNCGGCTTTTCCGNACACAGTTCCGGATGGTCANCCCG
+
*$+"))*%%'!$!"!')%)'+(!'"+#))*"")&(&%$*"*#')*(+"%!++!&''(!#$**'"'")#)+**$(*)($!)")'#(&'#)((!+"%(!'#'$&%"""")*+(")!*)+%'+$&'))$!%%*&(&!(*'(+!'!!)%+&*"&*+#&%"'$%!
@r5104
ATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCNCACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAA
+
711$"%(G"6"(983!CE,9.50.B<,;A!;F"!'*<@6'/C0'"9F,,-16#;A$DF1:F9E#7D;/(C>D(,8=3:D+*AG0-??4B@4
@r5105
GANGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAA
+
64(CA0;58%24F)?(E0%EB%C@45:D.4636,$09:A=!==98B,??G14@/
@r5106
ACCATTCAGCTGAANGCCAGACGTAACAGCACCACGGTGGGGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGT
+
192=&!E6=CE:-@-C!);<4)*71#C5%C<-2&?%G"&F/6!B>:+4(DD'3,GE/F0<-&4DCF%%#5+;F!2D?))AC;>#
@r5107
ACCCTCACCATTACGTCTGCAAACATCGACCGTCNGCGCTTTACCTTCGGTGTACAGGCACTGGTGNAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGG
+
E/F0@H3/9!3.6?!=7!)E%#5)B324+172D.%#4?7)"GC<.+!:5FG=,2&D@B13C9EEF-2&=9=40-05E;/$6)).'-F<)3=<&'7>H=?0G?'?&C.,-59!;?:'@-1,@'/42-EE?7?:>/39(.=5;
@r5108
ATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTC
+
3+2@918-A1&D662%'E1-19+3#-12F#321A=)A+.E'H?3F%FB1(@GB7@,F91!--.8-%E2"E!65:(*/G$01#GF!+'%7
@r5109
GTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATNGCCGTCGTTGTCGGGCGGNGATACCG
+
/=+!48)?3B!623($?1B==,$)-"C><?FD);-;3,.**53FB)H#/;231:H,*0*0?E6-<,@=<?!$!"$G=,!D#?F-+/0
@r5110
GGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTC
+
9<D8166=-.E$13*&G5+$;H-/&!FD,.7$4%7>)0#9)97#B,.0'(%,@6<1
@r5111
ACCCAGATAACGATCATATACCATGGTNCTCTCCAGAGGTTCATTACTGAACANTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGG
+
FF@/#%/7F*?>(4EC-<AAHHD7*BC+$F7@12:,FA+;+5EA;C>?9/5-6B9E:7>&*A19$=)5>'@+5#(7:4?DC:4=2'=F148GB#?(0H>F05@13&,B*%G9.:#-)320,??10)$)7)%B?3)+(4D
@r5112
AGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCCTTTTTATAAAGCCAACTTAGTATAAAAAAGCNG
+
5D)C-(=5D30'4&4(&('#9*H3D/+&H#%/0D@(,*83<F(CE149-;)<$=!'56.)&!')51G'<$.
@r5113
GCAGAACAACAACCCGCAACATCCGCTTTNCTAACCAAATGA
+
;67>8=A,F0E(C0112+",:#>=?36(+CACA;-9%*$.%&
@r5114
CAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCNCGGCTGAAATATACCGACGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGA
+
@3H)F/F46"*5'@6#"'@4G%:'=444%!6E&$.:.9!,6+*G3D99#2,G4DAA5.=(6<7%/-9'6H%:,C#E96':?)G$GC3H&5B(E2%"-31(7H'3;8
@r5115
CATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGA
+
+!*=6@0';74@G>%@B672@'4D773,91*:$1=*?:"+.ACB6$;&!HB*/.*$#+H?H@.>4?47!CH14#
@r5116
TGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGNATGAAGCCGTTAAA
+
8<FG!):?*2+,$#14*@@67D#!8;E!(#&:2%!1B('*,4&99:"H2E2G:,$!
@r5117
AATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGGATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGT
+
H<<7B,#-52:>2(H?2H:1*H6#<)5'7233D%)$H+9F.F+3B9'F0$G@7%(37.>$!F,/:5&:)#326&H3$?/=D!A;G%>5;(/,5.%.<?79<1*B764/B<HD:<78.(,&(@-,#01@C;AGG//&B38G..0F@<7<9F#H!%>H71(96>-D:<*7&9=)F*8)"-E9D5*2C96F>1811H?F:B8B)40AA-0*6*EF9G/%DC4)3@>HE)6"E@=<@70><;(3?=;D*4FDC'"D+H!?0-)E7C<<;5E1>'9/'F1=?F'*;=-C3501<'$32%7+-'&C1!-FB5G!;'!,:0$5*
@r5118
TAAAAGATTACGAATTATTACATGCCTTAGCCATAGTCTATTGCAGAATGTATAACTGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCNTTTTTCGCCNCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATT
+
6?7.,=/81+B%.<5A.;/D1$8:+.>*;<%FF$$,;-EGG5?E/".1*<6614.'=/(:8<<-2+#$>@=4!;-#?,3!8<@--51"4*%%'@-,360E$:D92H!B8#/;3001'0!','8*+2/%=<!'D>-+;)96-A!:"8$#7=F(G!=3E%C<#!4@/2):3=DG#;%D1,'9$/!>
@r5119
TGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTANGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGNNCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACANAACTAAGGGCATAGACAATAACTACCG
+
7H=<C;2)19)/)(1-="#"00*('*9-83;'4=:A:<C;5=D3043:3692$?9,B##)D5=3+92>>(/$!3#@,*>='3'B?(*!:6<(&%(G0(7H7*%B.09'55?G%).@8?15&@/++4!>39D9.5!(G$$!=*7<4'-F@&(46"E##37-C+;)$!)F+*()%&&0=0D.;HE*E73'>0&AAA-;F+B!/>=7D79>H@68!"962)7C>A5$:2.@2<(G=87=A1A%>C&7>DH.D<3-(B!51-1&&908DAG>+<5D)?;D$-E$,2,D>*8$@517!),4G(H)69C)(-7#F"@C=((C#)1E-H<;.(D:&$&H"$D80&%.A2+13#-35#7HA$-5-7%"#@*+'8D=495%C4G5!:H(;.$7,(/A(GF(+/98"=C9>&E/974=5,84"E)4G935&#G@+=(%D
@r5120
AACCGCTCAGGCATTTGCTGCATTTATCCTTNGTGATATCGG
+
0)'<E1(/,>",1C"E(&-42*C@&%<%?6D#6B3:EF&&#(
@r5121
AGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCCGTGC
+
D"#3D=$B!!(#1@CGAC@>=@@4-8/0+A2,171*)67>>14129##'>?BCC(+3*1!#B;
@r5122
ATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGNCCATGACGTAAT
+
#CF,.>A!EE@>:8*/@8,4=E-(A2/D1)6)H2F?(4A(@5$*C2FH&4C$(#HH22#4,5-%B4A+@.5AH6>:8&.;E#-E>"#
@r5123
NCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTG
+
&G;=<DC8@/*'$5=?B&"F!2//3,8')"CG.H!(9+:!@$9@C)#(@4@EHD2$E1<%&=;3!&:8*C*?&>D/F1F8<D=1!1672G,,+HFG.%$;?EF'<=-@:2!/.@FA'4A!3%HEE36.;DCFH)$G;:4>3.B>%F(%=$(*-8-?378F"
@r5124
CGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAAT
+
2B.5"'3/$20+89!+@%"#H2B$%>H$9(>;)@C)595GF&%D+-:>G
@r5125
AAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATC
+
F"'!E&D!8+)9(A/-5)@>47#B34C!//H1">*5&*+9C!H1C)$#-09EH"9>H7G)0)C"G&8+*B.&.@#C!2F;AH2'38/>%)31,+>F*$H@@1
@r5126
CTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGT
+
3CAC=5<C962'4C1:2<4==8CD/+49A08E@(7D/3@)7*5)4<G=51=!21E%AA3&'<E?#F4H-B)4%7$/-:?2C74/E?:!,:+(C.HDD0CG/.#A87/DD../F:!;620<;"#.H@1"
@r5127
TCCCCCCCACTGGCAGACACCGCTGAACGGGATTATTTCAC
+
?<-0//D2D6?/"EF>$DB(?95<*=!5<:#)/A#005<"H
@r5128
GACGGCTTCACGAAACATCTTTTCNTCGCCAATAAAAGTGGCGATAGTGAATTT
+
:)A?G!&$0)&+.(016A2C).3/8B0H#!3B8!75)+=!6FF'-A?/;@.<,?
@r5129
AGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGNCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCTATGATGCATCAAG
+
=$(!A"=#:*0;*@,D"5#A&?;8D3,B&.@*9':*G#93DF4*A.@-GA?;"#B051BGH8480'>#+67-=/>>@5>%<>H"==B:++7)2%D%=1'0,F!-#,C=87#($#A).BF.;3G2GB7>
@r5130
GGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCC
+
.=$81@B.E59G-&C6F022<?%68)H1F);6#0:>+H$/-??F=@!;5,D252A9B#B<:1+C!C:/H<0F)%C$
@r5131
TATGNTTTAGNNTGGAAAGATTTGTGTANTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGANATATCTTATATGTNCATGGATATTTGTAANCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGNATTGCTGAAATGTGATTTCT
+
*)&&$%)'')'"+"&$&%'+!'*+#'(*)*!*&&)!'#)+'+"'(&$'+#)''#((%)#**)$#((#$!#!$!#)&&$)&)%'*&$#+!%%'%("'"*'%+&%&+#(+'$(&#$'(&''$*%%*$+**)!$#"&*!+$"!(#('%'$'+'#!'$*$%!*)+%'+'#
@r5132
TCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGA
+
.-5+6!!>#1/%9-?>"%==G&=/@A::=1:G/25+%F99
@r5133
TTCCTGACTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTT
+
(-8;?;H/-&@B?@A4'350C5!"+"C/<A"?C;(/!96@E?<:/&*'%A27BE91>=6!%"+95+(71=DD7>>E8@F-E$9>@(C!@/AF7824=G><
@r5134
TTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTA
+
/4C6D.5E25B18AGHA%2%>=.&7*596-?F'686;7EDAE/7:.?"5!GC<%"!=>&
@r5135
GAGGCGTTTTTCGTNATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACT
+
'B/4@22HB714)AG4E$B!F+&AG#/5(3#')..&6/FH,7+H<6+G8!/#7C2-@2:4,!@9:C&,021-9%<F7D=+67*C5%'3557F6
@r5136
CGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCT
+
C'9;F'-*+E)1=A$<$/%<(3=)$*)A2=!:E)>CF60%GF=03CH5716=E>E2=>!4*&+?(?"'$+!GG'#/G0%+#+)7:&');@:E0*8"#+#!''9C>=A17/:7(/E;./3*5?@4.B)?06034<
@r5137
CTCAGCGGTCAGTTCGCCTGGCGTCAGGTCNTTAACTTTTGCCAGACGCGNCCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGA
+
),CDF/%19.)/F(E4("0?*0()6-H(DE$19/G/2960(*)+D?1;?&("=F3/12G;';#FE3C3=-'H0F#:<CC7/8;A8-:>AA)>&53A97*7$6AC%<A*-5)75778A?E%775!,06%>=/.1"H?3=3)$A4'G
@r5138
NCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGNCAGAATTGTCAGATTTCCACTTTTCA
+
$.600,*'1DE$@@89.53C"H;".+?-/##"GD-#5$"!D,@=H@(%C<#.:;H)@?H6-6.5FH0?27=#(8;<!#1@A9<".F(@0>G=E-=@D-#77;%D$#:-/;;0CH6=,,"#,/-7,,:2G)2!,=30:4+,AEBECA55EFD;9-D9-((DC951C+F/D348;;G9:3<+?G(ED6%E@$*>E)5H@35;1,:!9
@r5139
TNGGGACGAAAGTGCAATGCGGAATACCNCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGNGTCCGTCGTTGTTGATATTGCTTNTGAAGGTTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGNAACACAGTGTTAAGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGCCGGCNCAGGAAAACCGGTACAGAACTGCACCTTTCAGCTGAAAGCCAGACGTNACAGCAC
+
!"!!*)$+'*$!)*#"+($""*+&!"!!&$$"("(++*"$''"'$&*"$#%*$(!%')')"'%*%##&!+)$$*$&)&**!+#"&(%'%%"*(&"&)#%)+)"*)+"*'"!#+#+#+%'&&!*+)$*!%")%##)($)%)#*+$*()'"&"))$!)#&%'&(*(++&+!$+)*%*$'#"!'+*($!%*%#&'#*+$&'&!###*#'&'+'$(%(!%+"&)$!#*$'($*+)+%#+(*%(*"**))"*"%)!*#!))#)!)*$%&'!**!*(+*!$$##$')!)*$**!&&&#$('%(*!+)*))("&'
@r5140
GGNTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACACGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCNGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCAC
+
(("A4B:H.1G6A,*59@C)>G06*'&;35++<-.:D&##(*F"H3"8@)$!?80/"?-!H?E7!+5E7#G#9G!AG?AHC5.3<$>B#$&;H2%)7&<FB1F#*7FH"/.%<5>9"$8="(?:F>4>2"7/A14(E.>1D0F
@r5141
GGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTG
+
2<H;6/+,0@/#9!H&'5"E/370273#,3A-<D19/=AC($0=90=!>"$,1:4$
@r5142
ATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGAAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCNTGTTGTCCGGCAGGAAGNTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGG
+
,4FAH=7?2-3921-(=74G!21D64-#/@+.+1$<);&4B&*C!+@#FA<>0:/C3B=0.5A15=E*+5%(&(;.H#%2.=30."!:D,$E0'<D&-8D!(7<">,?91)A9+%*@0BADA-C>F-FC@2(&.9@E9B=DB0D0&%DDF@69-@D.!5-"5#>)?.H&.'0)@'7%=8;D=452<'4@A+9.)>1%
@r5143
GATATCTTCCTTCTCAAAGTCTGACAGTTCAGAAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGCATTTGGTGAAG
+
F,G($;>:ED!6/BHF6H=D&5.B;G9''@2&>FC!%)8.#;H/*7-$2<>E97G@$/6-)'C%4+?"C(E8)1D&&'+5,D32%$F5@2?65$?9!>8C/=B;>.4)>DE8@=260F#D=H<1*E*,,>3<775E+(#>!+#;%
@r5144
CAGAGCGTTTGGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGG
+
F=2?&4?9".G=9(G>6F/9;"18&(A>7."4D+??-C+7?5<57;4:(E);+11C;$<2")00"'0?#<;C9D&?CHG(
@r5145
TGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGNCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCG
+
C6'&+-A*3$<G02'&4&+87)?>5D>.3*+#$'=%;48'69!:>G$-0F(G787'F$F07A7'&5>E1*);$&68.1@F:A9($$0053%&982@:
@r5146
ATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGAGAAA
+
0!AE',-9>+">,0@D&<04AA$<"++2%E1<=")@?0E+>C43@B,?1D7@
@r5147
GAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCC
+
8:DB89-,6@3727HE%0('99A?H678B-*@3'3#*(+H2*:'
@r5148
TTATTGTCATATNGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTATAAATANGTTATTCTCCTGGCTT
+
2D&?(C+&D2=)":E'E#/&5975(7=>20+@<?D:#G1)>+:F<);1';9E6BH1&<1E*0A!F?3**!G2.26>1H:")=
@r5149
GACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAANTCGCTTGAAATTNCTATAAGCAGAGCATGTTGCGCCAGCATGATTAANACAGCATTTAATACAGAGCCGTGTTTATTGAGTC
+
D*C613/&:9FCA*F.D@/24:$D:1F<12#(487ED;<G%%)#B8G-'0$.'?B2%$#2%C&D75/</."),G'@.$-(%@9';":4F<=-"H$7+$3';H6&>62,:D-F#9&<:1>2@9,$7$A$@>=?D&9
@r5150
ATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAN
+
5/;$D2HH,'%=-9#+FC?:>E7#?C7"4B*)$G5>#=2&<CA(%75/>@;A->/''95G#=5#5G%0+;,8*9E(57<8*,(6A(,#&(/:69-1=:F)3(*!8$3E?"*%/797+H2G-#,<
@r5151
NTGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTT
+
%&FG(>#F!4.B*0H>/>;@!69-@!,B"8)&"@7**6)6;7#?"<,?;(8!G>!7:503<AH4/;8/3<D#*C;8'<02.$8='1<?
@r5152
CTNCAGCCGGACTTCAGGCCTGCCATCCCGTTCCCGCGNAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCNGCTCTGACATGACGTTATTNAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGNGCTGTTCCGTGGCTTCCCG
+
%)!$*+('&!*$&&))+*#)#"$%++!)$(&"$&*(&#!"#&'"+(%)+')"&)#*&(*)*$'%$+'"())#%%%$!)'%(!'(!(#(*%)(+"#($"%'!'!&""#&&$$!$%+)+'$!)()'!(&")%*#!%&%$##++'!*&'
@r5153
TGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACGTATGAAAAATGGCTACGAAGTCCGTGACTATCTATCGGCTTATTAGTACTTGAAACNCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGNTACT
+
)5!=!/@%:%5&E>>=#=.@*1BABB*!2+0*,8-?+>>9H:4*D&<,:?./$A3)-<;'C=F3@8DGE#6!3/*(;HE/<8E<6?%2CD"D9G6C0<''1@:+*/$G-)D8:G;E;<D:0.7"5E</$A$5-;!,7!.=H%B.!>,?!&=B1H+&H):?F
@r5154
GGNCNNTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTAACAGGACATGGTACGAGCTAAAAGAT
+
(*)'!!4A0;8&;6.2<!*.F)3?A:.9$&5EB%7GC'D@!*F9E3>,86+,EC&8?;<"@:&A"1@>8:<4G@
@r5155
GGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTC
+
.*=D%?5!1B2A/<0B-%+G@%$;56>C&;3!6<'E*@-G>@+33=7.;#6
@r5156
GCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATA
+
G2'!<30C#(-38E%@+-5A18ABGED'?1FG@,>A<C47?225>#
@r5157
TTAGAAATGTATAGCGAGGCAAAGGCTACTCTNATTTCATCTTACATTGAAGAAAATNACATTG
+
:"42E%@0<>F1"%<G2E&>=$+86"AH#-#B0@8'G78<D,*5EC?F%!@D"E/D;<C6?"-A
@r5158
ATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCGCGAACGGNACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGNCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAG
+
8+%"8@)5&C%:,/H@?>FB1:4#7;6AC;B();03D@0>;,-0?(0.3:-4@FH*0+/.CAC<!+@&F;&@51"1%%/=+:.?8G&#&%?#&'>456E)"6C'-*<;$4%<*8D?9%HH'*0@.)&<,C;:C@1;:%E?H0F1D$:#F83=*G',=@A*@E;B1/
@r5159
GTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGNTTTGCCGAATTTT
+
.H-B1>??4E1C8D)$G$(9(1;=5?,F?B<:7>&73<;-=HB-'#H36H.E'0>71);?1
@r5160
AGCGTATTGCTCAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTNGGAGACTCCTGTTATCAAGCACTGCACTGGTGANCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGATCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGC
+
-5>.%.2<C?4/G6>*#&?4@>"+>6*718222#0HE%"7A#"-=)9>=1'&/.&34",-+B2B%$12"4C2/-).');"C94CC&10@;//37/1@"@B&:(8F45;?7!&D-&DF/82:'>>$-!"/&)G&A5-11")=)37>6=6(F,?@5'..$B9A0$3><#B:'141,*+H:5)9-&&&?9HD18FE-0*%2%*7(+G<#G:;%(1('?!!GF(89(?E.99)4(<"&/*(B2B
@r5161
TGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTNGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCNGCGGCANGGAGTGGAGNAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGG
+
+41'%)$6#*0*F.(9<*@&.C%83$+&G'=7A30,<F<#-(9):@?<AC05)@<.AH1HD#(-77@21;>'B#3"%;@4>D3E/C=C)2'<&B5!4:>%!8:;(G.@58%BD-6(!++/>H"B*.%3+7H=E/6A6=+/4/(?"+.D%6&@?$A2F-2#H7)=3;<+)<(<#/G28F-3<5(&0CE%D3EB+-D@@?G(1E?;/*HF20%F
@r5162
AGTGTGAGGGCGANTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATNAATAG
+
F!/F&,,#.@0)7A8+9G($#3$:$2B2A417A,,2G>DB',=&54.#.-89).7/C3)%7=&#"C;$$C/:H:/6=G16@5<+)?=B71E
@r5163
TGCAGCATNTTCGACAATGCGCTCGGCTNCATCCTTGTCATANATACCAGCA
+
0/5&A:&,'+0+A@?A;678,=51.:',=7F=7C'C5+9.#E<C/BBH@E-9
@r5164
GNNTGCNTNNNNGNANTTNNTNCNATTNTNGTTNCNGNCAGNNGNGNNTANGCCATGTNNAAANGCGCCCNACGNANNNNNGNTNNGCNNNCNGNNN
+
$$$###!"$!!"!!##!#!$#!$!$$#!$!#!#"$"#$!"$#$#!!$!!$#"!!$#$#"!$"$#!#"""$###!!$""$"!$!$"!$""#!!#!#!!
@r5165
TTNCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATNTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCC
+
G'!B1=C8)H0*?0=949<:C#/##FB3103/>'-/*+2913>C*B$>;(#0!*=:(F/#!'B*#A17H$(0#&>990&5,@=9.E;!@>0*;#40-81"/6HF-C>G81A371"-3')G>1-E58/#H>9(A5"
@r5166
ATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGNTGGTGTGGCGCAG
+
HA@D)2?-!<9"*/&B'%96D%%!!F@,=FD**:H+%+*2)@>>H18"51=E23G6@3.(-,?!'91-;G-"H:37!?%3#@A0;9$-G4/#!-69>"DE32!D$/D?DF3=A&.4D6
@r5167
GGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTAC
+
",/.=D-?6!(GC&9F*'2"!%A7>A22&(BD(D$7%HGF=G30E-8!:@3A0H4:5.EB#-CDHH
@r5168
TGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCTAGAATGCAATAACGGGAGGCG
+
2B78!;E#/1$36G>%H/'9"*:4E%'8&6%7./C.>91%%?-%-+%+?'/<-D5,==':=66"E#6
@r5169
TTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTTGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTC
+
'.6<FC57F47.)0&<6@5B%#=B30FE38.+%!?C7.?0#+04"87$=*>91&*G*>>$?DF+(@GB&#(-6?88%71@C27+"11B1;;A>'>.H,4?
@r5170
NATAAATTATCTCTGGCGGTGTTGACATAAATANCACTGGCGGTGATACTGA
+
"1!8)*%9;+B7>DA1,74A;D%+$G>9+=B&"7%C?>9$+=-;0$$-".G?
@r5171
TTGCACTTTCGTCCCTGGCAGTGGTCGNCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGANTTGTAAAACCGGTC
+
9;A$%@8/@#B?&H#B:,E;?>D0@E73?/C-6*%>@6H"E5#!9'0>%F+=2,#5D-10<>@/GDA'.EHD86&%,&4:+B>)'?56!F4<<;-&EH/D!1)03)&!:C)1$F#!*$'4@BE9--=E-=)248&>>:F+:@:>-#1(B(8&'
@r5172
CCAATACCTGTTTCATCGCGGCACTCTGGCGACACTCCTTAAA
+
-5H1".,7:04=8$-06E*532,<-E<A4#18ACF&7ADDD.G
@r5173
CGGAGCAGTTGTCCGGTAATGTCCGGCNTCCCACTGAGCAG
+
@:7(E(3E.9"A;D',6E<.(F4@,)A*-/%9C#%)H;!1C
@r5174
TGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGANAAATAAATTACCGTATTTTGCGGAAAATGATGCCNCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCG
+
":!:2%<F'G62+.0G)#/A72*67."C>+E*.A%EEB<G8"@62BE?G:B1EA0F./;54()F99E<BG$200?5&*@HH.74C?H'F.C-4(*2&5$=F("DE=9+:->@-B":&.$')C@@5C2G$#A?7='!7!;E>'C2=/D125<A2*#%/5H,"?,A&9C2"-"+((-0=14
@r5175
GGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGNTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTG
+
-*C@$"5E:$AE@".6-E*C<=A(4A9=/+1+"->=4+))>@9#H#D6!51(#AE>574C0B0B.(!@/;5"58<H:B@!CH(+/ACB!H..#->D;(;08&@#6,,!%+,GD)#!?B7=#.#E6@<A6$D:-4!7AE8@)87,$*42+G4E/'D8/3$-@B,19<!81C+6),AH)$H.9/B./$=81>-
@r5176
TCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTG
+
<?A:<,)@4H7C:EC*;)+$17*D-/*-7;#%#?<G=$$*=7;1#GB,#''=B?G?(+447B!/'%)9&2D?*94(,GA$8/)7G::EA/&%/F)150--1B<#87#&9@&#8&!;&=F!<5+'2<5(("H@+6#G+.):,3FC
@r5177
TTCTTACGTTAATTTGATGCAGATCNATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCNAC
+
'#"&+'$"!*"(*$#)''"#$#!#(%)'!$*#(+!(%+'!""(!!)%+((&&&%)"()'")!(++$'(!)!$()(*!%!")*
@r5178
GNAGNGTTNGCCGNGGTAGNANAANTTACCGTCACCGCCAG
+
&)%*")")!$!!#$"(#&&))!**!%+!$(""#%*##%"$+
@r5179
TGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCANAAAATTC
+
;FG)*H4:9>"'(<9@*:1)#.91!-5D.6G0>0C)0F082H
@r5180
TACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACANTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTC
+
"7->6E!=;?59<A=,7)$#/!?.5,83D:,'B,'+;GFH)#>!.C!@2:=#0HB'*?!81C)E#:FEDH+'G,?#,"E//#@+&H5E"/5DC','90())4;513!?059?==A84#&G@:48*4B<;$F1>>G;;??H0C;D<FG.2
@r5181
CTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGC
+
@2CG=4"(GCF(3?).?!"0H396H3</.640-FE,;<G;11A884?"$'FAC&
@r5182
CAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTNAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGGCGCCTGTACGCATTTGGTGANCCGGTTCTGCTTCCGGTATTCGCNTAATTCAGCACAGCGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCGGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAG
+
$2&6;"&B!(5.727*G*"5.6H258/B>C&;F=A5!85(*2&+.">2%>A:2E!$";2DAC(=1+D$63?8!/9"?61E16+F+=.!D10D;.@&.C?2$3C=,.7*G>;!.)C)>!>5414+2E9+7,7"8*%<A+/#..<=F4/-6BG7#4@F)2?50>1&04=1@FF8B!F!G:CA(#8-D5(/,53+.>%*!D&!%%-<-<9%/2*'HD@$0:007%7@<9>;:F)F("%=%2)?ADC"AAH+$=$!75/?G/5)H8=)0A4B9>@-9AE%5/6/2*B*=/*:6,8>@=H&%/%".-%*?%AF)&.)1A*4&!96#C-G>1D-,G<A<*5$*C,14@(+H:C2@H?*E/+%#(=%>3010>?A3(5'%'6F5A3-!=A2A?<C9B70E*D"8'0F%?#;>37,C@@663>(D5@#/-;=0:006>0A#/<,/9
@r5183
TCAGAAAAGAGAGCATAAACATCAATNAAAAGTGATGAAGAATGAGGCCACC
+
:'A*0%93-F2044H':4-5>)3A,@,$?>!1*B=%6#H*#&H,*7/@6#+"
@r5184
NNTTNGCGATCAAGCCATGAATGTAACGTAACGGAATTATCNCTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTG
+
!"%$$+*#!&#'!""#)#"+&%""%(&(%)+$#+!*$))(*"#)*$%%'$+!#&#(%(!#$$+())'+!"))(++%$+$)#!$*'*)##('%%'&$'#'+!%))
@r5185
ATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGNAGC
+
B%D6D#G=G07:E2!HDD.,*7=$)-6(19B$%8)$?232+4=1=@E97HEC!%5+>?$041!;D.G%E.!7FE/BB5,.<F#
@r5186
GTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATAC
+
=;@<5@"A2-F>((B'188-.4'1+(>-#?-;@6<C;7A&6,1:(3.&6
@r5187
AAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTT
+
&F'D762<A""',GC:49E&A",31";@7746:0(.@6',EA@1)6'/9<:/=%2784@#,C#E!$?FA50;($9&G'&2$E<:D5)?4<@("(G,,!;BC/'BE@:/4/5H503;A#=,BB),"2!<AF**%.">CF
@r5188
TATTTCTAACATTTATCTGCATCATACCTTCCGAGCATNT
+
2++/.=)BD,26)DHD-?23!;10B3@H@/>?*+:*2H">
@r5189
GGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGNATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTNGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAG
+
C&2'#>4B*987@F!=F8,<:09,)>:(%A$++#@;:7+,?,?61<(1@AB*-38G-0%5*6@E8!(+BC:,456(-A@D"?"->-*21>@&@=4->@%#6E$;:D#!-G/.*->.)*='9,6=016&2!*47#"$B#B:'?0#E)6/(5.-F-'$67$44-@>*134,./.$G$4
@r5190
TGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCT
+
-9F3*#GD,A7=<6.G(*3,<E2%BD#5FE+*>47+2;+(#?E:7$EF5'6B@.;5AB"H+'761@#E%7#@!=$*?(
@r5191
ACCTGNAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGT
+
0D@;!A<G"&:&D=2;99@%>/.F,-EB&.HC>H((*BH0$G!44.*.#
@r5192
TTGTGCTNTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGG
+
:'::G.5.B-$#/3!FF7,0>A)D3:H5/3!2<34@GF,/#:#8+6#@)/
@r5193
ATNACCNTAANNGCCATCGCTGGACTATCGAAGAGTGCAAGGNGATCAAGGCAGAGTACCAACAGAAACTNAAAGACCTGCGAA
+
!#%%*)$)&%"+&*#''"(!#'#!"%"+)%!&%)*%!'$)$&!!)+#%)&*)$#*$!)+*+$#*!"&#%(#+%#&)+)$')()*
@r5194
CATCANTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCNGGTCACCTT
+
0@5*'E.$=4=9'CHD$63B&,D%G'324#CH5A6($?B,H:,.)F$=F/>/,B&!<(;"062G7FH-8H27=*%2A%4'"1?B3-
@r5195
TCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTNTTCCGATGGGTTACAAATATCCATGAACATAAAAGATNTTACTATACCTNTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAA
+
C7A(&H/D'%A%919&082#9!!#<(:5!&>3DEE*"B%F-12+H4!4H/3"G:+E*>)<!=!77D&4(H.)F:"6H)E9<.$AD5B!3%F,A*)%C@CE5(,20"B;#@01-EE0H*971'2A3;&$0'D8,5)$0!C?%!!/H$781(%E(5&#F?F&67#&/?DA<*#$#9D9G*4><>C$H0H#2G/FB$%F=E4$6"7H0)$+6F"G/5H69'8@H"4"E
@r5196
AATNGANNGTCNCTNNAAAGAGAGATCCTGTGTTGCCGCCAAA
+
&')&%*!!)*#)*&%!+(&%&'(+&#$##&**+)%+'"'&*$'
@r5197
NGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGC
+
$07/*<H)172(#"5=$1@.H65.-06.:!5#-#=>(+'B,=:?%,2!E8&&9!5&?)3@9#.F31H0.98?%-$$)/3(@-F"6/3:B,+)C9
@r5198
CTGGTCGTTCAGGTTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCATGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCANTACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGG
+
B"8499<4=+DB1(0(D$??'>0;?")(7%C2%1,<.H="23829()<:$7+?H<5$-@&"&*F3F<+'=E@0D%$E45A>H:.1#:-E-H:8AE-@?C5/98=*)#G88:7@B)7=0)/*#749"AC87AA.)7B3@9G@(-4?H@!!8-<@+FCF,'$1=2;@5E3@@%E$751A61+$ECD)A-";35;G!+5$HE?F)*F&*1)G3D';E9"C+9-H1$H:6"G+-(&CF3!/0HE:)./=(G'GC$.90*#GF63&'%D>=-2>36B#$
@r5199
CANGCNTTGGCNCANNANACNANCCNGAANAACAGCGCCATC
+
(*!"#%$('%(!&'$#(*)''"('*$*%(!*$$+"$&((!+&
@r5200
TCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCC
+
-&<=<DC66:0675&;H%!;G$E*+E4;<+@CF922B*-24&32A6G'?E*>=C983=13/1)B"9@?#"(=ED$-B"@,$8828*9(-5:>'->D!E(#?E!>"?0B%>7D6.2+"BE=B1
@r5201
CGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCNCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATT
+
(*)'+##$&#'(()"%"!'#$&*%!"+$"'&((*+)#"!%*$*'%"(#&(+&#%*#!)!''#'%"&"*)#%(!)$'+(+&+#+#%%'*"+$#+'((%#$!&)""(*!")%((!**$*$*%)!##)*%(#(''("$(''%+)*+
@r5202
AACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTGCCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTATGCCGCCGTCATAAAATGGTATGCCGAAA
+
&5&6@E5=&#939'DD<B";.=21!0#)E7HG'9(@94(>C2#,,-B/&6-9D)="6G++5!CF.4D2'"C)/412,=(<>9*AE7.H83H?;)(A$G'HE39/5*=.75:(4H10";7H4"@*"=:?;B+7213;@%,1$&D<8$"+
@r5203
NAANGAAAAAGGTNAGCCGGNCACCTGGCAGGGGCNACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTNAATGGCAAAGGCACCTGTACGCGCCCCACGCTGANGGTTTCTNACCTGTACGGTATGGTCACCGGNATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTANGCCCGTTGTCTGGATGCGGTGAAGTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTG
+
!)%&(!!)+))%+!")!&+&#!")!+*"!##)+#+))+#("(&*&)+#&)+#*"%+%#*+&)'!$#&*$!"%'&&+$(#(!("+!!#(#)#$'')"++$)#!+'(''$'+##&(!*%$&+!+#)!)$*$%&+"$(*()'*%+(')!%$$*"&$)&'%++)(#(&*)))%'$*')*$#')!'%'*(+++%*(++"*+"(!$$'*(''(+%*'"%(%'$#"*!#!"')!)(!')#$(#")$)&#()*'$)&&!!(+)$%#%!%##%%*$)*))&"!###!))")*++!#('%#)"'%*'"#*#%)&!#*&()&)(++!(#!"%($*)%(&+$(
@r5204
AAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTNAGCGAGAGACTAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAA
+
?#*FG+@+1D/++F-'+;9%@!%:!'-;17,&(/1":/4,)."'6DH7?%2/09EE-09)'7C=?52>/@4D+-8&2E/A,;E4:9/6.=));G,0-2D
@r5205
TATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTAC
+
D00A>;"&.2F2&1$8(@28E&C*+8)F7)D!+D13A"/(7B'G:F;<<>D#!H03B.G<!05*'65.3=-A??CA'(,296E"D&;?)8"A222#-(;6#,G=B>16**;=:#>;F>0--@)+20!+24F,AEH,B&$9,DFC/10(2D2E*&=AH(&
@r5206
NGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATT
+
*3(C(><";2.$97E9%#2+<A%=.@38/ABG/;6CH9C9D#C<23GD/55;)B;5-D>H>&0EB7@?4G."3924+*"3G'995@#BG1@0D/,%0;)+79*#,&?5H1!##H*F
@r5207
NTCNGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTAACCAGTCCAGCGAGTCACTCAGCGCACTGGTTAAGGC
+
"$+!%(#+""$%!$(*$+!'!+#*')*(%'$%%")""#"$'$+&!(++"#%$!#)&+)'!%()$+"!++&''#'*'#%+!("''"*)*$"+"&!&%"'&*((($(''(%'&!$+)'#
@r5208
GCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCNGAATCACGGTANACGGCTGCGCTGATCCCACC
+
).(&;A#20'+?'7:/--3H467%,/BF8B97=04,<6!.>-?/C5../#7:4.$*=&F?5D'='0'C5B)%9'
@r5209
CCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGC
+
9@*@!.8)"$+E":*7;8&HD;G>!/@C&>$%*>&3.#,'AG"B79!@HD227?3((B0..3'F<)5=>$-%*,!0<$B2D3,G))E-D7BD6-#(0:<-"4601'<.-#)64F$5"117)0.2%"GE'8)G&$B25.B?%644(G1:E!!*&G5>-$=408!.$<@+B-,9?"D:9;C#D='#HG,+<G<9/66
@r5210
CTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCT
+
E7)BB2:'1A19.H$%4=86C))H&3"&1@*.((-'@>-(D1"4H>9:#GD.::<7)"3<4B"E:=D,:,7/HGE+F-*(!<)$&<1/6
@r5211
CAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGNCATTC
+
2%/?H@*0?G:(...!>#7(ECDA9&6,3'$'8->2/"1*%,HC
@r5212
GAACTCAGCCAGAACGACNAACAAAAGGCTATCAACTAGCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGT
+
;1;72/4%=(C%8++=;,FF,.6DC9/2;.C70=(602%6'"BC6+F:9,!#4B,H<3B(A;=@H:4'3D=H?;2H-,8-=!8
@r5213
ATAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACAT
+
!AB-1(74,-B-04%(6>1&*5+#-E.8>3A3-%;*88G:3A#%.6@D+++)B7$1B$"@D15CC?!-80?82"1<;=C704*G(?,9.!C/,C!&C(@/
@r5214
TTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAAT
+
+%##$*(%&)+*'#&(!(#+"&**!(()+'$#")+('''"!#!(!'!&++$(#&%)!*"'%+%&$$+*(&$!&
@r5215
CTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTG
+
+'*++&#'')+$)$$&*!+"&$*!(%&(!(%&&*+!!''('''
@r5216
AAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCTCA
+
.:-=;<5A:@,2(6F(4G!H.#6:'?*D=-)H'=(D,C9@/2:1=>=>5;#/10@&,9+1:$4DF*>.;#)&4'H:"@83,%9".&"C+&735&>=..421-H>H18"$H!8A?(6'%CE6.?/8*;3#/H3A51H0*5#H">>"><5$3
@r5217
CNGTCGTTTTATTATANAACAGTGAGAGGTGAACGATGCGTAATNTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTNCGGCC
+
$'%%$+%)+"'$!%)!'('%')*$"()#&%""*!'%&')&#'!*)("!"%*#+(*+*($")$)&$&'$#"")+"#)(+&%#($&!'"(%#'+!#(")$
@r5218
TGACCCCTCCAGCCTGTTTTATCTCTGCGNGCATAATGCCTGCGTCATCCGCCAGCAGGNGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGA
+
@1/;%"A3G6A6C$61-"E'&H4@95/.940H:!"3H,5-152.B7=6=54=+/?A3/1(&,,:;5%/$.B+?1+;="%%&"A:>=%G3>0G@%0G17.?0A&4G:6%,%-)9/+&AD57>:'?1F%997-""@E%/018@,GFC"==9/$//:92$(?;93&48#%-E6$22!(:+35(53H*/03CH>(,?,B8'031F<H6-;)@!4B.63?):25/B?-A&;>H::.(<GC:
@r5219
TNTTGCCAGAATATCCCNGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCG
+
=)5+7D0'7;H0>.&0>:A&H3**A6,><@!GG##:H10D4%)+#DF*-4$')9?F#C!=)8
@r5220
GCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATAAGTTTGTGGTGAATAATGCCCCT
+
E>)G;'1-"C#C$1B2;B.H7?.E!$5@52;C:/#."1,D?D;3@--4B4#8209;A?D;/>5!&,F*/?7>)@712(/!D+&3G".<4"9E,=
@r5221
GGGCGGCTTCAAGCGCAAGACGGGCCTTTTNACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTC
+
2;.387!FAE"9:H.C<:;7/C85A7B*>*!67)2,E1#7"G119'$@*$BH@,*9?E%E9##%(.5=7*"8%(G:B'(7EC1+;&:7)51!.D1,/0(4:FA&'C
@r5222
ATGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAG
+
#"+*&$!!+%+&&#+"%%""%+*$""%"&#*$#'&(&#!$$*()"*'%&!$"!"!+*'($*$#+*(($%&*!)$$&*!"'$%"')#*$+&%('$%!"+')&)!'"')"+'&$*%$%!"(&!!$(
@r5223
TCGNATCTTNNGNCTCGTGCCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATT
+
($$!'$#&(!!!"+%+'"%%*$+*(('&**!&)%)$"++"%!&%&%!!)!!$+&&&*%)+'$*"))#)#!"%"(*$##%)#!(&!&)&"+!*('!"'((!&&$$$!)+&)#'"%$++&%))*#$)#'%!!+!*)"+)%%)'*')#)'$(&')(
@r5224
CTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAA
+
->FD5#0)79?7#!.513D92D!'-35)+C4F><(@/2:?<E$$.E&$-E;
@r5225
AGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGANACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATNGGNAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGAAGGATGACGCCGGACAGCAACACAGA
+
0B14$-FFCD1+AH=B"74-3G4,':H>*76F=C+>+04;%6D'B;BE*"@=?@:/,@H*)*6*B>F8(06-G4D)'93B,)<B+'/A">B%0,%+H>:2@&&4)21A$//G(C9A.G;)&E">#(FC-'9"55&2H/"!%.5:$2,"E(3*'&8?)=,))/D3'D%&%"9A87>48-4@;F4(!
@r5226
GGCGATAACCAGGTAAAATTTTNCGGTAACGGAGCGAGTTCAGAAATAAATAACNCGTCGCNGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCNTCATCACTGTTGAAAACAGCCANAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGTTCCGTGGTTGTTCACTCATTCNGAATGCCATTATGCAAG
+
+&(#)*&(!)!!*$%(!%%!!&!#%$%"$")#(&)#"#%)()#)$#+("+"&!*+")&&+""#*)$"%*$$)+'%$%+(*&&%&&'"!+$"##%*!$*&%$)'"&*%"*"%("#"$'***+#&*(+)'#$++!&$"')+)"!$!'*%!*&(!)%!'($$%$%&&("(&$)#(!!*(++'+)#!'#*!''++*#)$&$"&"$*#+('*&%*"'#'+*+##%'!(&!'*$"#&)$)'&#)!*)&"'$+&$+%"'&$(+"$'*(%*'''"&#"'"'#'!%'+)%!*%#*$%''*&)#((%'**%((')+!"%&&&&
@r5227
TGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGA
+
4(8&/%019(6BG(E&:$CGD'/"6!:B(&>7D+"D>H;BC*%#2
@r5228
TCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGA
+
A?C:H@=9D7?<::4D<G+2;$'7>GF5-'G81)$"8*>C7<BBH'E,62*,1.?-H
@r5229
GATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCATCGACGC
+
!4==?521$*'#23A;(A539%B9F*@4(614E#F7GC36!G!+.(<6B@8F<*;*F"'<&"%.!C)?<+/,$"36$F(,'';/.)%"(72*>BB7H$#?'**+@;H(:H*7B/>D?)#8#-)4;(1-/C*.?+,@3
@r5230
AAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATT
+
7D*<2-B&)E6>H.;(>>":5;8A8H@>E7)<G9*-7A*8)$HBB(5:'DE"9""$9):GCH!3"%F)D7-5*(3DB44+/B*9>8H+=9".F(#A-A9(6*
@r5231
GCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCNATATGTTTTGTA
+
42C6;*63&;?(#=A&.>0988@-C,59'@6E:$$'=&DH45H6A"&!</7:A=(.B7C)>A+&+%"AHA$%A=@A?%:;AE)FG@C%23-%*>0B,+#$881F3F80*;.=?0!4#DF<=.%*B46C//G';/73%
@r5232
TTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAAC
+
+))')$%!)"$$!$!"+*%')!&+*%#(+&'(+"')%!%"%$*"&++)##&!+""*!
@r5233
AGTNNNCTCCATATNGNGNCAATACCCNTTTCATCGCGGCACTCTGGCGACACTCCTTANAAACC
+
!#""!''%*$*&%"#%!&+(!$&)#%#($!+&+'&)&%$#!"'"&&)(%%+)*'$#*"&!++)$'
@r5234
TTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCTGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTT
+
-F)=8(:D2.C&,;EHA0<%:49(9*&;)*B?6H)9.&$*?@46@G(!A::1&E;("06-3'&2=&,@;-8#):)G-';D8)*=1D6%H#$986*5E=0;;9@;5.$=(,'5>9#CF1DDACB,+4=*+7?1(;*G<+74>F9**GH17*CB$<9,=+-92$%?E!(1>3'-*-%9+=.B5DD"(@G!*3#6&&>),<&7$6H>.%*F0<=6
@r5235
CNGNAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGG
+
""&'*+!($&#%))"))&!!)!()+*'((#+*!"*"%)&$))($)(%*+&'+%+%%&*"$(*%!)#!!$$)'!*&&)'(&#(+!#)''+)'+'*(%
@r5236
GATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGGATGAACNAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACG
+
2#GDG07./0D98:D!4''(?#*2<&3HGC#0FE45CB")--B%C-%7C>5?0'!6!-69)E%5=3+#!%@A;:A%,**3;(.6+=-=?C*B;
@r5237
CCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGA
+
>2/4=CA93AB?D7489?H!'+"!H30D+>E-/1>2!&C%9,-&FA"EH;:B1;C21/%5FHG'>F-%3C,/,BG#8D8G"G/&<G&<)/*>A4,$3@-FF2CGF:1-E&E3B.,;0#+0D47"2.#E495#E@7=934%7%$#?C&?E+,/!%-F&E57;)E24G84(8%%8-7<B#HD9<$%6H",%F$(9(;21?5%=>;7#C-BD@;'#G8B,><H#7>$<4EE;/BA133,;A7AA)'-()<A:C:C7!'!,3*?+"2<E>CG+@:@F3!::)44-.>
@r5238
GAAAATTNAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAAT
+
5-',H6@*8:3+*%0?+(0B3.>%!1>!(,)A=05&A#"'>(74,A$!BDF/EC0#6)$4='"5,@470A,$
@r5239
CGATATATTCACTCAGCAACCTCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAA
+
D"<2!HG830B@#(@(?"C254'77>F;,"1:0!;9FFA/&+(?$C*7)<43'(G7971%$G(FD2.,)6$4E)B'B2#%>'C=#8?93;
@r5240
GACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACACGATACCCACTATCGCCATCTGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATC
+
5;-$D,H5HC-",3<"5#,3046)/0E'?AH>)8!C1-7':88+<"@6+E:&#2)=+.G8?@A;%%!1.104*:%7C%37D44%H2;8"'D0:@H;FHAE74);%50)13F,D6G5%#?="3,1,<;E"D2)G#<64&275"F>4-+)571;"32=!334H4H,H:%#)3$("D3)7?8H80AG+1G;1>'A6A5&,:&8>:GC27"#5,3*95'5@<<6>++3?224>'@1>'9(<8):-<?BDF?;),C8?<@<?."F(0:7&F7C2C
@r5241
NNNANNTCNGTANCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTTTTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCA
+
""#%")%(!'($%'+*!&(")(++"&(**'!$))+"(#'%('$%+%''(%%#+$"(#)#(!+%'&&##"%&)&%!#"&'("$&%+)$%++%*&(#!*(*&&('"'%"+')#"
@r5242
ACTTCCTGTCATGGGCGGTAGCCCTCTAAATCGTGCACAGGCTCTG
+
'F%3"+%8=*F>4:&D)%!@A?*D<9'!8%0?D*!0H@;6.B1F&E
@r5243
GTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCG
+
(B;"'=%&&%+>#3F1B94>%'19$=)BG@3B5935B8?48
@r5244
CCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCNGCGGTCAGGTAAGCCACACG
+
,@H:B2&2G!7=2G)01=F>?,238.GEB7.?2$0CE6"@6,4%B@%1&/%2%2DD+$A%"9)#!6=7E'6!3@A@
@r5245
NNTNGCGNCNGCGANAAGNCGCTGNNNNTANGCNANGTNGCNATGNNTANANCCCNANCNNNCNCNGATNNTNNNGNNANNNNNNAANNCCNTNGANNNAGNNATNCGNNCGNNATGCANCNGANNNNANTGTATNNACNNTCTNANNNANANNNACTGNTNNTNGNGGTCCNTNGTACNNNNGGNNNNGNGNANGGANTNNCGGNNNACNNANNGNANCNNANNNANAACGGAANNGNCGNNNANGTNACNGNAAGCGNTACNGCTGNNNNNTANGCCAGCNAGTTNNNTTNGNTTCACACTTNCNGNGNNGCGNGNNNNACAGNNTANGAGTNCNGNNATTTNCCCGNNTNNNNNTACTCNGNANGCANNGNCCGNCGNNTANTNGNTNNCTNCGGAAGNGNANNCNNANGNNNGNANGTNANNNTGGNANNAAANANCGTNNNNNNCCTNNNNCTNGAGNNAANCTNGNNCTCCNTNNNNGAAGANCNNNTCNNNCGCGNNNNGCACCGNNNNTNNCAGCTNNCAGNTGGNNNGCNNTNTNNANCGNNTGAGCNGNTNTGNAGAGGNCGGNGGNNCATTCNTAAATNTAAANTNGCCNGANTACGNCCGNNGCNTCCNNNNNACCGTTGANTNGTA
+
!$"#!$$"##!""#!"!$!###$!"$#!#"""!#$$###$$!$#$#!$##"!$$#$#"$#$$#"!$$###""$$!"!$$"$#"!!!"!""$$"#"$#!"!$!$"#!"$$#$"##$"!""!$""#!$###"###"$!"##!!#$"!$!$##!#""!!!$""#"!"!$#!$#$$#####"$"$!!"#$#!!##$!"!$!$"""$""#!$!!!#"#"##!"""!#"!"!#""$##$$##$$!!$$!"$!#"#$!!$!$!##$"$$#!$!#"""!!#$$""$!!"""$$$##!##"#"$$$$$#"$$!""""!$##"!!!!""$!#"$#!#!"!#!$$""##!#"!"#"#$"$"!$!$!!$"$!$!"$#""$"##!$!$$#!$#$!!#"!""$#"!#$""!!"$#!$!##$!!#"#"!!!#!"$$!!###"!"$#$$$""#!#$$"$"###!!#$"!$$#!"!!!$!$$!#"!!!$!"!"$$#""!!"!#""!"!$!!""""!#"!$##!$###$!#"!$$#"$"$$#!!"#$"$!$$"$!##"#"""$##$!!$!"#""!"!#"$""#"$"#!!#$!!""##$!""$!#!$!#$$"!!###"$"#"$!#$!#!"""!!$#"$"#"!#!$!!"$#!#$$""$!
@r5246
ATCCANACGCAACGAGGCTCTACGAATCGAGANTGCGTTGCNTAACAAAATCGCAATGCTTGGAANTGAGAAGACAGCGGAAGCT
+
'"%')&+"'$))#)!#*&#*('+!#+&*'$'"(#")'"%(+)+%%()&'%&$%#&)%+$((")*!)"&)!'%+'#*&!%#)$%##
@r5247
TCACAGACTAAATAGTTTGAANGATTAGCAGTTGTGGTGATTATTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTT
+
5E<-D7(987H*,<FCD9#;(%C)1(7'>3')@<DB:%>;=1*5E>78!9G)CDF-!502@@%0#F9/%07.'1%?F3<DF/B!.6/9/EA,C*8)$@)2>,:*<A$),?&*2+;#G';F*E>>F06-'=&H.E$H&1&D+/>(&/#-A,@*52%&A*37;@C)!F%B*6:-GG(?-+8B,*873',@<.3DA80
@r5248
CCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGG
+
:0&'3;D58.'7793H'F>?""G@?)8+G+6)7C+6F%1E&5*;+
@r5249
ACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAG
+
H#''1;86D"E,<2$E5.#->;8G2A#G.?'FE1#1:(*@3A%#&220+)E*H?83:G8/EG$:03,&F4")AE(:'H!2B1@9#GC5,8GF&7(F$/.'FA3?G,0!9&4@A>-/-+<<*A@>:<H-36%9?3=AE0-<"*D)8C)8H,0'GGA'7)*=7?E!2DE9;;
@r5250
NAGACTGAACGCATGAANTATGGTTTTTNGTCATGTTTTGAGTNTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTNTTCGTTTTCTCTAACTATTTTCCATGAANTACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCT
+
&;G<.<$C<B33**((=E=!7%&*?F<032$)B38F=*03455E>!=$-<?','%"#->87!7;E?@B:$;6-98@$*/"6?-D$F1F&5;B"8725&@&2/;3A+(%-:%AG8GD?>8*#0*).2G.#0.0#%"1$)(@&A!3E.3@;BC;!8?(;6+
@r5251
CTTTTGAGGTGACGGTTAATTCTATGCCCAGCAGGAACATTCATGCTTTTATCGGGCGGAATGGNTG
+
7H?.<>A62&&7*.)(5A@&0.7E&>??-.7"-3!5*$EA3$8@;#(G+)?3<.8-/C'$,A9@*90
@r5252
GCTTTACCAAATCCTNCAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAANGGGAGCGGTGACCCTTAC
+
A=<4!#;9+;/,F(H&7)@=(49<#!9&,C977E'*03+)++CE99$1C6=<'C4%$/)%09*3$'-)E1/3D+*D!A
@r5253
AGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCC
+
%;,,0+=-),3B"3GD,":6(&+>5G?$!(*=FCB299+72*$0?$E&B6GB!7#D*-&7A--)(@D3+%B<C5A%/5G:*78G1A@<0?<'<F073H>&%)319-3*@G#
@r5254
CGCNTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTC
+
?:2=*H*09+#'5.54B1"%)27#..F"$,"1D>+,*3&?
@r5255
CAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGC
+
2:(<3C>B!4'3'B3/D-1#*H/A009'6+#),4!FB5H6#7#D;G.H*1F@G'.HE;5?;2*>A
@r5256
CNGACGAGAGACGTCNCCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTTGTTNGGTCTGGAAGNATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGNCTTCCCTCTCCCCCAAAT
+
#%+,8>/5*?0$C7(C(?A)()):H<DB?39':-&$?/-=>():72HE9?<9%=;*@96E<2G180;F$8D9?>,$;?CA>B/,D!C+(9H"7B*),9/*<#A9#+/%6(:4"BE7?3D5,++0-C@E4CC*(!,F/"9":#3%$H"0#.7H+"$D58!8#0H>0E-*0%42C@)15#HA.;30,%.&/C76.1>52
@r5257
CTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCC
+
H=37A*D/+D(:03A4:C8)3:&45D>";C!C88:;7'43'-;.-04
@r5258
GCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTT
+
G!EAC&/3!/0,2,.:<1<C0""CD(F>=G4;F2=*FGF"$&=(8$$EH)H'$HC<:4>-*,!+.E23+D4<+3"#>&'F*-@&6=#8)E6"
@r5259
TGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACAC
+
(+&()*(!)+"($''(''"$+!)!$$%(+)!$')*#"*&()'"!%$(+#*+"(*)$"'%%%'#"*('#(*"#
@r5260
NTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATC
+
")+$")"++&$%"()!(%!($'"*"(%&+!%&)#%$$&!("('(
@r5261
NTCGCGTTCTTTACTTCGNCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCT
+
#+*)($$*(%$)#!$))#)+'%"*)+!%#")'!"+!$()"!*+$%)*$'"+#)$'*%*"*(*'+&%#)))+(%"#'(!*(++)%$*'$("%)'"$*&%*(%"&$!+$)#"%(+')#*)(*%!%+(!%"'(**##+!#&!***"#$(!'"#
@r5262
CTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTNAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTNATC
+
!*B<C%;(31H"%9@/*9C#>2%3:F<:1+)/5*6+<&7FBG=#&1G@7099(;#.@@!.,G&!/D@36FE81E8*0(D3A@=D?3A@1012)*/+3292->70H-/!E6)&F&@4*+4*#C-!4#(;%A66@@<>AC$6*HD<.D7.HH+02/36@G&"(++:06?/F'!G>+!4;"F3;E/AF+<3"4<<4*&69#H+3()/;1C:+<>7(.+&*+C<$+H::)*
@r5263
TTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCTATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTNTGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAA
+
0FEG?8"D>2@AF('%>C(=,25BE<3@,:"A82>44#$H8"5/?$F%#4%/7H1+0!+&,76F/)<5A,)+<7?@+H.6:B4)!(->.;1>=H+,(@/B!?5@<=+:AE$>0:?6<49FC8A?>(!B)D;,+@7EG#,;2(#2#"FC'D%F)#GH>CG>0!+"-6'
@r5264
TTCTGTCGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGGATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGG
+
$5FG.A<;B7?&D707&'@@0?AG:3$*4#/:$<@*F9='2A(42>469B.5.EG0>B9F/"5@E8F5=;%4*&EH@;H'/6>&9=2'<>B<"!6>(A5G7&?901@.55:F/(8H)*H/'41G7!H$%<$+.4
@r5265
TTGGAATCNAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCNCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCNCTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTAT
+
E)9)!!)B!B1%%.@0<*"16*!F1H7@7+.63.D@;$(0.*1H4=%-13A<=@C>&'<,09*>3D+-)!1*C@/CA-D"5AAF.3!0C>:$71'$:&@!419H.7?3B+%&8<7G33#'>GE>-:6=0E-1E1.&99@"96/="D9G;A?+&G4,D:
@r5266
CTTAAGGANGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTNTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATA
+
&B3()'G84;!8,9+2%6::6&,CEC94=.!6..)5&":;>9.?AA14>(1FBC-"(=1C5#@F<."!8!B7H,=CF8>'<0GCB1""2''%?&37!E96#%CCEH!B3/G=E,4$8.53D;&19>@26G)-6DH&.>C=//=4B!>FB.7;0,/4:73%++&-"5-=.)<""<9!2)/@#C?HC>0,?$D2CG/-/->;4,#.B4A#A<9+?&0/B$GG)'/5(,/HD(-B0B+2F6F&C'=G+8-)>&F#1,"8#8H751?*+**GGD),2!+=69)
@r5267
AAATCTNCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCNAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTCTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTNACTCAAGTGCTTCCCTGCCTCCAAACGATA
+
;=+D@1(34B:AH5"$2?6*?1-(FCA42"8#A0$(FHFD)@FDD50@$H2H,9B78!FEB&GBA3D7>H&:474/65./*AFF),#:+9/0>6?":8@!ADE75*E;A'(@$@(**7D!88B#9(C+@F.%;0C=(&EC3HB1=!*F(;6#/>8GH9&A';B>"!230)<(*G+<=8G:@B;2#/,&<)>8.;@"8*,A>*C%1!&&&1-.
@r5268
AACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCT
+
BB0*%H&F$&%<B*01:8!F%?FBA*":#F;;A'C-,(*&'5(8)(
@r5269
NANAANANNTAAGNCNNNACGAATGNTGTCGCCTGCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCG
+
(*!&(!&'('#!'!)!$+)$"%("'$+(#''$!*!"(+)"(!%)++'%#+*'*(+$("*"$$!&!)')+#(+#&+)$('
@r5270
NNTCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAANCAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAG
+
!!->(0C4+;3150HA7H:<957@=5A"&(3230>8@+2;HC?0@'A)171F1CF?$)#.:3D.5;9"04%5G!#>0=@0&;991+724)'6%7,<0687$-2%#FA))2#F!/9?;>638@174E!3
@r5271
AACGNCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGGAAGCTCTGGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCTCGGTCATGCCGGTTGCCG
+
','B$:<G##((+5687E7E5A+%<=@3827'*(1<A-%6).C97*#2C$'G!EC'"2$G2%<F#7EH/9.8&:;2$D6G*#57)E2="@463";D7C0DB>60;1-)/B&5H36,-;G8>'6-26E;?9<E'%'(A.<BD2)3A0%&6-(&F97:<.G)?(#/F:H:(8=3AF:-=#'
@r5272
AGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGG
+
0@C14AF93-5$A#!GC;:)?+?)4H88G/75,@)#8<)#.&FE)'0(:&45.!?$@CB
@r5273
ATTAGCGAATGCAGGGTGAAACCATTCCCNGCATTCATCNTTTTTACATCGTCTTCGCGCTGGTT
+
$D"!-+&86:EAF5>F=H?71/<'*9#(78E@7"*93:.AE&F??;2=A1034>A+,%"#<A63B
@r5274
GCGATNATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGGCTTTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTNATGTTTTGCTGGCATCTTCATGTCTTACCCCNAATAAGGGGATTTGCTCTATTTAATTAG
+
D?"H!:.'5@B%8<,16G+A..5@0'<"C=HH**4GF4)%/979!1!*5)<*"C9,.C!=.@%!2G8FB6!1E&%C;/C7>87A'&D"'&@;&)&*?-$+G!A&&9)5>E-"H7@3*"-E&+A<;%%F<*08$,0""D=HHC*-+"'4$,)*.*<@*G*&83!*AE.+$DH2<$G+D!#64,.B-'76/3&0-;HE$9=E>E9
@r5275
AGCACGGCGATGCCNTTCATGACCTGATAACTGCGGGCCTGTCGTGT
+
1G-"G1$:E&*('5=;.E.,'F>0+>;4?:?A2"B&-67H<D)'GB$
@r5276
TGANAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCGCTTTTTTGCAGAAAGAACAACAATAT
+
5=;6(5-8$?A.E:5"/#27G@C#)6C6/D"83/71F;%=:)C%%$938*H*<>)<-/=D%0.9?E2D'$?=DE-4%13$(==C==<!C,7D%E(DG*G0!3,27<*D"*98?%2D/:9D#%28:*672=<GA'
@r5277
TGTATGACATGGCCCGCAAGGGTGCTCGTGATGAAATTCAGACACAGATGCG
+
6=%<!!;*;C)'09<A1?B,?F=DF#*CGG":$$C-!=%*(03C*@:!H$5D
@r5278
AGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGNAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTG
+
430%?1<12(*<6916&,/-!.,.)*2HD*??%&</E>!!0;">HEH1$)CF2?8,C<=*65@),#)*<46$@.(=CD/@5"#<=C8;=:0.7G7#:*A>25/(;)7B*>6)'7F)9#">(@;G.!BG8C!7CA&A%:?-;;9+=/-<-@',!>77/A>F($E&+?A2)BC#H'=5=)#/;/*'="HG:8A@B;DBH>19G@.;86F321
@r5279
TCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCA
+
+%("!!%*!%"%$#$%#*(*$&'#"'#&**#(*)#!"'&))!$+''#)#!!(+&)%#&#((%")+*'&(&$''$!&!"'))##(*'$+&&*(
@r5280
CTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCATGCCATGCTTGCCNNGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTG
+
@H5-3/E@"2@..2C/#8E2<E>-*#4@#9(#3H-D2<D31*+-4G*8:!"BAG61::H(6!9+C'8@-<B+9%>?B687<:EC&(/A379++D;'",-&#$'B+.820)26*AF;--)DC2G<BC6+#:27&!,1F/9#F>%+=<E*&9'EB@001"C1;B?.2?496=A*<%72*'"-85#/>EHC.!AAA05<+A2+E9('6$++F*F-4@1$>@/
@r5281
ACGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGAGGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAAGGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGG
+
!<93)8-9!1.=?'=27-(C97+(3DA"7@%8+E!,/**C@*.CB?D6?(D1(9)>H08&.;%+GC=%B2H&%;.*E-:H"*&4/3!%H<(@&(F/(BF4>.5<C89;;A1$<A!=B&5;:C2C@
@r5282
NGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGC
+
!2**</88+H3)A+H'GDF%$#8>!3:#:2,@=(&:2:,B;;?4&
@r5283
AGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACTACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTG
+
BF(?-7(".B+81?5:ADC?7354@#H*4).%BD4?AH6)==3++&<1=@:A3:HH0)B)1C/C,+(>&:)&#&#';G-7C!?37.?C:GD1='D$*%?@B?2DG);".*:<G01+9;78*D6:'<)D#52429;-/=657A@5<E"(F0"+)1<=G0D65H<2=69)0$(@A%?,5,3:,83F8!2'%5"G=$)04@;*#0-:EG/.E)B85H(;03?*6HD$6<"@1)6<=7'0+&/1$1G!3?:<.<5/;>:;C4#GF4;F'
@r5284
AGCTGCATAACGCCAAAAAATATATTTATCTACTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAA
+
6*D87"*"4(8/2!>F4$(/21*.AH:*B@(%@3?#G7**5<(<&4+/1CA"A%7=+G7:@3!"F)-=)+!#(/"EG@.(-G@1@D.1,89E#8)'5&%>71%)(7AG6E=8:C*#D1:!G2-
@r5285
ATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCA
+
G9@08A@'#+);5DCDH;6'.*GH."/5(FC+$4;AC;$<")@&3F+4!+#1"-D)C4('*B59C7-=:&2/C9-'+/263A7>89@=2'-<
@r5286
GGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCAT
+
6'F#(3#=;@!CBDE;!,D,G2=8>7G51C&:90H;1;B&$&D%+(
@r5287
GTNGCATAGCCGCGCATCAGCCCGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCATTCGTGAAGACAAACTCAC
+
%*##+##&!#((!*#%"%$&$"&()$$!$#+*"&#)')*%)%&(+$'$$$!))'&+$&'$"!+##+)$+'#'""%&%%*
@r5288
TGTATTCATTCAACGAGTGNATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATAC
+
2(@H%:>7@$FD)/@%).3AE5?).7ACH>&&>H+#G<-FG90G2@5+0"CG0#&?9:%8$'2;@F=7&0&=$.)%3?H!-C2,:E(6'&?";./=4.E@6>'D!;#F;8+BG(+8:7@+%DD4"E94?-$4,7@:'G5+958($&5?-04(>5#
@r5289
TCCGGCTGCTCTNAAGGCGGNGTATGTCNTGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCT
+
D(/5,&21>A@8%#AA$0G=!=:*+.238H=G9&#31--63#.&24D4H##:*)5HFF!4.#*.?4$+0DAG&8%'$'0,$;-*8C8-1!5*.25E$!+121DE%:86-/84('57GH
@r5290
AGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCNNCTTGTCGCGCCAATCGAGCCATGTCGTNGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCAT
+
187>83/#!3=5=#B+,,G9=6>1%)EB;BE2=82)*E2:$=427;?!7G%@<0%(H,5FH*E@EGD++BH2ABF%:3:-@8B:.:*;@.$*(?F6DB($-"%"G0A)9H*2#=**-4"H%.0.79@F1-0'#-0DC!(+4/08(=*2
@r5291
ATAAACGCTTCCATCAGCGTTTATAGTTNAAAAAATCTTTCGGCCTGCATGAGTGGCGT
+
;.9:1>);(<"3#&(6&9;DH@H8!<=#/)3&"@0="G)HA"=<1CD5./;<*$C%9:=
@r5292
GATGTCAAACNTCAAAAAATACATCATTGATTACGACTGGCAAGCATCAAT
+
E)>GD.>"@508E3$C;FC69,5"E&=4)?.649&'.>;%(>0(2./%%"#
@r5293
GTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGNGATTATTCTCTTCAGGAGAATAATGGAAGTTC
+
?,F'!2GB0%H:?2.CC4>C"*H#(9B7?!=3&",$'0+0,5&)?8G2DC).(6G:"-45.DG&7.4,,:6,BC
@r5294
GCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACNTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGA
+
ED,"8<<')CGC.@:.:0*>";A3,$?/'E85GC,E774<;3<#/D,90.(>H3)94#?/$-C&*+F?E;+5>&%E-),*HH0H=%?7=">1'<.%E(3.9'019$E".7(7-600%:7,>90@937&A<#%,+:BAAB"
@r5295
ATTACGCCCAGATGAGCTACTCCACGGCACGGGCCANTGCGAACGAGTCGTGGGCGTACTTTATGGGGC
+
(+(*(%)")!%#'(++#*"&+$*#%$##("#'*$#))*!($!!$"##("#*%(&!%*%%&")#+$)"&!
@r5296
NGCTNNACATCGGTGAGGTAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAA
+
!&$(!"'+)($+'+"+'*#'"')"+++&'$!!)*'%!)$$)%)#$!(%%%%"%&+$+(%!#$!)*")&!+(*)"$!'##!+()&)*)"")"%+)!($(&!&+#$&$*%)&')!$("'$*"(&%&"!'#(*'(!!&!*
@r5297
CCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGC
+
-+1:19D4;H2$-4/CC3A9+;5@&.'5"E@A),+@3>19E.92@B5C1E!1'0--H6"&GE>1D?.$09D:/:CA*F.FEBA(8)F"$4?9(3#&
@r5298
ACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGANAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATGCCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAANCTGACGTAAAAACCTTCAACT
+
E83'C9:*$DG./'%15$1#%+F)B1?7:H$!):&7-<=@+@8=+!>$?#=>5*3749++4&/"H*E/$'<"D;<D/9>#>-:H0>AE<B.%'CA"2.5(3/@BH$""!F4?$G>,<+?=+/$#::-%>H+F-'H:-(D>53>E<)HG9(',-0:5")'FG!);::85
@r5299
CCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGNTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGA
+
)-<05(/,0-'(#2ED;0*42?@HE+.*H#0=.G&@1?C87E<B%!)7-9$HF,3?8'6+C$/D0+B;'=)G"=F:=$#CBH*0"'?4%2/?%=9-A/<$%/31H?.*B.?C;"G.-./H27/>%,</7<=!G)2)=//
@r5300
TCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGT
+
H@--):@1*7<#76-9).15.>..BFF-!6&=(A-C46#8D%7/!%:)2)$;9-+H9C6;":FF>H$:?<.=%=):($)#15AGE1A&G=$=B@F5#E#C52F1
@r5301
GAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTNCAGCCCGTTCACCACNTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGNGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGNGGGAGGCGAAAATTGGCGAACGTCC
+
%9:2CD;6=?:<B@'E:@5GCH+$F?8*>*1;:!AA+1*2;7##*5F)6!0<;3)C+/HC/;:!DB4*CF@"=6B!#<E*28F$<@.,559>/=)/%*@!F@D?GB7!-CD!:5=37,,9.(<C0?7".H>-0>B3-=#A$%71671F5G=62#<5F=85DG+>/0,?4G
@r5302
TAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGT
+
,,-E,98FH'D$!=;;/4+)0<86,%)A!5)A.4=,7F&=+';HA+
@r5303
AAAAATATAGATCATTTTCTTCCTATTGCACATTATCATGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCA
+
,*+7=53B:@%),E%3$1,?"7;>&G57?A7+#G;$9;;DE03&F-G<35&"2C+B(GH1(25!!B8438A80G6H(ECC=:8)#3,.H2!5E*,(#$"9GA/H2C+0($"#G98?/59C$-*AE=@!&2!8=1+@FF?)1'2)0;6!CB3;-8+(H@,:2%2H-'@BD$?,H:<:1(DH:?5FAH9'.#;'5%F762E3A7#<.+>#?G88G#;?'9&H$#:
@r5304
CCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGANCATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGC
+
E6!<0?>#+E(9364!'GF5%58D%1F<+,D'537)=/3C?80@-/74$8&+E@@+,53$51G3:.?!&'<9"1*(+7?>&!1=&-)@0D/
@r5305
GGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGA
+
<)@AA%,)*.=5$*#FC=64%#8/60$,3D$EG4@?<C5<<E?D$4?@?8+%,;$0!H%6,#;G.,>D6?=84+;#,!!+@-;)EA>;=*DG!7CG<:<-(,0<$*58&-=.&#+/4!"#F"E4?8(1>8A3D-G/3=#>+7@+&.7*H/@38*-<E9)(A;"'D.D40FCA<B0**:&@#A162?:&1',(<H(H(4EE,C&A8,7H++G>.$6-
@r5306
CTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTC
+
>:46)9E<49<E7$'H?#4H0=%A;$1%F:"A=7B58)'<;C/.!DDG-
@r5307
GCTGNGGNTGTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCAGCCCCTGCATCAGGACGTAGCGAGACGGAACGATATCTGAT
+
'!)$%)(!"#+$$##+%%!$(++)+(#!(*++)+'!()$#+#'*(#!)(&"&&!(&%%!%&##)!($&#$&)*"((*'!+&!)&$"(!)'#)+%$&*('*")'#"!%%#"%+!+"'&&#+(%$#+"%#$#(*!)+"(+#")%!"$"))!*%'+&+%!%"%($%*+++)$$$!%'%(#)()'"++!+*(+#'&+$*)$!+$*&)!&#&$+($"(!++"!(+%%$$*#*'$*"*+%*$!
@r5308
CTCCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTACACTAGCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCANGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCNGCT
+
$"?-E6GH%-&:FD2=,B7">'H%>E)/!+%#/=2C).F8'.G>D5H'C#>=(H''"3>GC&H7$$$@&"!G?D2$)/?.H"=.9?(@?3A%($2E=HDF8A=?&1'48=?DE-!"1+*<C,HH=;>$!1B3>9#@F+D=*8A#:84,:"CC7&&3..;2D!7D?#";7A4G(/%(7%2)7(1+=C.;7,>/G!,C46'@0@%%$1E%-97(G?C:$%2C>@?#<B,8/H8$1!F>$?("$5"B7#3@81&G>8,
@r5309
ANCAGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATC
+
*"C>@6'F3*63FB6?EC.!B?G?#667B=/'>;,CF,'?A;DF(7#B
@r5310
CTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCA
+
G("?8.E,/(>-:<<)6-0*&#00?.(4$)9C>>2E0-+F*5-*$%;<!.-+
@r5311
NGGCATGNGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAA
+
"!$!)"$+#"!")($&*%'#*($+)!++'*'&"$)')!(**!$%*#+$#'%)(#''%""#
@r5312
CCAATGATTCGTCGTCTGCGAGGCTGTTCTTAATATCTTCA
+
>>B;%3=:BGD3/!01,+CA26.H=>/#/$338"@>:<6,9
@r5313
CAGTACCCAATGATCCCACGCAATGACAGAGTTGTTNCGTTGT
+
52&/?90+2!2%$03!B'<;4+/H4=,:D.48=<7#56<FH:G
@r5314
GGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGC
+
'D9(.A)D#0'D<)A((>A+"F%-(/3<:"F'=FC;%D"B-$D),>E<"*AF93#G717+%A-B;$-"<:G$B(*-'C&.D014+'+
@r5315
TCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAAC
+
#,,-<7B5)38;:*1?(-8>F5#,0+.F$!,21=$*CBGG/'AC;8!%:F,98
@r5316
CTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGGATANATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGC
+
-8,)/?'"#CC"5=C5"G.1#900*B#=C@4'>-'-11#E0)44B(4B3>90@8B+5;G0=$E>(FC/A.64/0@*?4!7,C$47B;?/17+>:8"AD8
@r5317
GATGGTCCCGGCGTGCGNTGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTC
+
=*/&4D#3'AC?*8.8A2'7'39@B@$9313-0B>F+<<37C-07'F0:,93H7:E.(A3(;@A5EH,=E4?-27H"/!2+,,7<E>)B>?AB5B)07&G"D/%H
@r5318
ANNANGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGTCGTAATACGCGGCAATTTCACCAATCNAGCCGGTCAGCCTTTCCCGCTGCTNCTGACTNTTCGCGCCCAGAATAAAATCCATCGCT
+
)($)"&%+$"#)'$+&&'&'!"+'$%(%'$("'%%%+)%%'!(+)"+&!'"*)*%"("#%$#*%$)'""*&)$+"'+$!'&%!"!()#$"('*(""#&)+'&"&)!"'#'$%#*(*+$#')'(&!*')'!&"
@r5319
TCTTTACCGCCGGAGCNACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCT
+
49"@E.9,*8&B4-$,,A@?4E.>*1/H2>!2HE7-?5@7H*C,?7A2%8*BB8H1;3!?C*5A/-.-069C@G-8%=*
@r5320
NGANGCGGCGACCAAATCGTTGTNAATCCCCGTAAAGGCAGATG
+
"(''+*")!!%#%&#)'+&*!)&+&&*%)%%"'$%(%$*)%)#"
@r5321
CGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGTTGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAACTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCNGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACG
+
=C#E%$"-;6>9G=)"B:F!.76%81CA3;HE?+7--6*%GH<+C;31%=/;*$0)<"&CG4%"5H1<+<E".C716=A16>,,63&&:)5;?'@*FAF:5(?8*9:<+HC;<G-8@@99%CA5G8(,13A#*>>4C*5?>+A"72=:=<*!G78:*>AE6'G8D(@98/-3-(;7<?(!B14A1<*G853E"E<;/EA(B3+2"G=,61EB72:11#FG5!$H)D/3;>=3$H>$,:,!4G1H2"FC&2(<?&D4/8#;0#06;3@#1>C'06=#H&!D1:&G+7#8>BAC4F'>6<GH9D!06+-B8.B?9:2=@@>14=F@
@r5322
CTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTAT
+
@1>;"+0GFC);/=;#)*+$G)E3H"&#62*+B>:4#HE$
@r5323
AACGGACAGTCCGGTATATGCCGACACCTTCTGAGCAAACATCTGNCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCNGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCANACCCTGTTTCTCCANCGCAGCACCGTAATTACTGTGAGCCATCATGACGNCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCANNTGACCTGCACTGCNGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTNATG
+
!2%"@CH"%=F3DDD:A$<=>GD/B.E</D9#?*/4&%F$0A/3<B7BF1D,$,/<1;:)3734*(A"A,G"-,;'E1;!6-1C#H0H7!!;2E'E28A@,@)&0+0&>7F1D?(FE?F(@(4@+D&@A&?6?,%$'+,F7+F8$<&(-.F$9*!("61'C-%>/H@-7D7C+$@-=9)@62BG9))H8>><7&.3(BE,=H=#E'3;?G+4#51GD#F/@,,#4%$)?9>=&.'2.D2$45@'5&>'0E+"*./BE90D-BBH456A0<HD3E2(E:*1@%E+6B585-E45.G,41;F#=D73+68/AH$$B*GE*@
@r5324
GAGTATAAATGCCTAAAGTAANAAAACCTAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTT
+
9@F=+1D75%=#:6'6),8;C!",-@!4F!!?C"C/E/AACEF%"/36=<+0"+;#B@HDBC0GAB
@r5325
GGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTNTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTNGTACGCAATAACGGC
+
-3@H$("9A)B=E5C(==2@<999(.E'B/?0H<''*E4$F0@(.BF9F/.=;6.&B76!@*'!FA&-8:B/;&"BH,G>49-4BC/%>A0AFC@=5?8-66/<C,-/AE-:0=:C9:*&.:D
@r5326
GNAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGAT
+
+(#D?30.*-5E2>')-D'#&<E$+$>($#B<=41.H-HA?+E,44*$E+82>
@r5327
CAGTCTGAGCGGTTCAACAGGGNCCGCGGGTGCTCATGCCCANACAAGTGGTTTAAGGATGAACAGNTCTCGCTGGGGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACNCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATA
+
%+'%#*#+!"($($&'%(+*&&*(!!'*&##$$$%*$)$(*)'$))$%!("!&!&*+#")%&($+!+'""!&*"''($+&#&!)+$#)'#(#+**$*"&(#'&!)#$#'')")!'&$+%(($!!*(#""!*$)#$!+)$+&)#%'"##"%+%!+!*'%%!'%*'(!*)*%&"'!'+'("($#'%')+%+!%&'(+#+('*'$+%(+%')%+*)')"(+*)++#)$'$"*&
@r5328
GGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATCGATGCCGGACTGGCTGATGAACTTGTTAACAA
+
H$6D*(DF>)/E4HAE!15B(23#&,9?40;34(88AH'')9(&0H8*725@91=!,G/%=H-&0A25HH<D*4?D7(,!0$'',%25=+;$-B34#B<(2/4G=
@r5329
TGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAACTCCCTCCGGCGGAGTCTGCTCCTGCTCATCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCT
+
C:4H**?0/3(D11:18'0(0)=&;?>5&-:/3E68=F'5(!D%,E'>DB98(<89154?/0")F)GA)$'+A)40>6%..3-:6<B&$@B'50,)20=74,D/,B+35>.%C((6/.DD./45#%+@9D>(*C*C6:#2+8$A2"FF<-*F*$/?!-2E<GG;=D!>BC!3A"G4D>%#1E?"-/,8"5H96EG@=)4H8422+D2
@r5330
CATATACCCGTGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTG
+
=&4:<"8B/CA1<86*A(9F+-0$;%CH26.77A-B=.<%1!/H(5D.8/80B'1C1(;/=9G.D#(4-60>#!$&)@.>G>,.4D@!&,#&/&7F)$>!?:"
@r5331
GCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCNTCCCATGTTTTATCCAGGGCGATCAGCAGAGTGT
+
/1*;2F@6-2(B2D"2!;:(5955AG/'?333'<7;&5""FHFE$>!56-1A7?3A8252)3!<39=!//92(@#@%9?;A;#9/:'>20&*9-6@).95:C257/
@r5332
TGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTANTATTTATTAA
+
*/?$7B;0A;<3/9BC72E(3BDF$??=*-2..!<2=G@!7166D?7C2"9@-1E.(C6,)9!(;7C"@?.*&B23-)H++7;D5B+A@<
@r5333
GACTTGAANACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCA
+
!!6.%1.*:B71$45F*&-2#/6"8%H)H/A2#$1$3/E!!15H$'&6FH6$0C)))8%68!G<=AH1"#HD1"*"
@r5334
TTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAAT
+
9?<<)0)99'%=&(F<14.+1@=EA%*:;37;B8+C&;;6./)1#)C06AD*F#+2,D>+$14(%&8?"0(2GC-D9(B0
@r5335
TTNANTGGNCNNNGNATNNNNNNNGNCTGNCNNANNNNAGGNCTNGNTCNNNGNNCAGNNNCGGNCNGCNNNNNCANGACNCCNGNNTNCAANGCTGACCACNACCTNCANNTCNATGGAGNATNTCTANNNCNCCNNNATTNNNCCANNGTCGCNCGNNTNCNGATTNNNATNNANAGGATCTCNNGNGCTTNNCNAANNNNNNGCNTGNNNAANANANCTGCGNNANNTTTNNGAGGNCNTNNAAANNCANNNNNANGNANACNTTTGNCAGTCGNANTGGGCNANNNCGNCATNANNGTNN
+
##"$#$$$!!#!$#"$""#!!!$"$!!$""""$#$$!$#"$$#$"""#"#"!$!#!$$!"!"$#$#!$"!"!"#!!!!"$!"""$"""!$#$!$$$$$"!$#!""#"!!#$$##!#"#"$$#"#!$#!"""#!#$!"!#!"$##!!!"""""!$##!$##$"!"$$!!!!"#$!#"$"$""$$$!"$!$!$""!"$!#$"""!###$"$$!"$##!$""!$!$##!!"!$"#$!"#"$$#!!##!$$##!"!"!!""#!"$!#"#$""#$##$!$#$!!$$##!#!#"!###!$$!"""#!#"!
@r5336
TAGACCTGGGCAAAGCGGTGTCCTATAAGNGGATGTATGGCGATGTGGCCATGGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCNGGGGAANACTCNGGCACGCNGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCG
+
"(':$5EG%.(E$7C.'&FBE.(@?F('>88$074610#5H72H8">;H0,74%4'*DH33*895D#H$#,BE34(*+00H*CE:BC9"-$1!196-@-G:*3C;3&B2=4&)C47#%.AHH.G!<<%+.BBCHE1;)+)*%4BD'C$?=C/0-(;293+-AHD4354@+F!3!)$"*F+:@B/1"E
@r5337
CNCCAGAAGCCACGCCCATTCGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCNTTTTGCCATACCAAGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCTGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACAATCCGTCG
+
&(+++$"#+)&#!&)$)('"%+)*!"")"###'*""*('#+")$+&')(&&)%!$('%#)%##'!(&*!%**%+(&%%+)#%*#))$!&)&$+!%!#!)'+'*((!$$($$)$*##'**++'%%!'%(!&'#+&'!'!%(*"$!#'&(&+!*+&$)'
@r5338
NAAGCCTGATGCAGGTANCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGA
+
#=<;+$39E9;-)4/=B$7CD*1C.87'-5E/'!G%"?(?8#?:5=F(=5E>,40&HG.$03"6F7F$156*@44)>H<
@r5339
CACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCA
+
>,)E7FD7;-7E?2G7A;B#F*.#!+:A9?3EH-B&1+?8"B"+C*;6-BEA<!)#A("
@r5340
NNCNAATNCCATCNNNGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAAT
+
!%*!(#&%&*$&"$#!+(*%*#%'$%!"*+!*$"#('*%(%'$)&&*+%'%()#%($*&+%+(&+!&#"#!$$+!+)("($#)!)
@r5341
TCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGA
+
%+%"#!#*"!(!+!)(+%+"%$&!)""'#%'##('$+!$()))*"$
@r5342
CTTNTTTCCAGCATAAGCGGCTACATGATGCCCACTATCGCCATCGGCATTGCCTCTGCATCGTTNATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAAC
+
+(*)$*'%$**(#$)$#(&&%(%*&'+**(!"$))'))&!$')('""'(!"()$#"*"*#()'$"!!"#$+'#)(!(!!$&#"!'%#(%$(!&!)(#(#$(!#($!)*##$!$&&
@r5343
CCNTTTANTTCTCCNTCACAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAA
+
&%!%%$*!%"(#)*$"$($+##)+#!+*+'&)(%'+")''$#())*"&%+"('&#*%*$&!"((++"$)!(!&+*&#(''+($"%(&&$)"#%
@r5344
GGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGC
+
GGF@?-8G*F;5$!>0H0:94%2H-:#1'C).=;./3.4&/HB@A*'""D+9(4A=#3=92(@*+BHHG&/3#7%H+39H6E1%(,+0+3!4A%,*B7?'0?$?D07'9$3
@r5345
GCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGT
+
2%2#5?2%&'505H*/%-C!H*='25->:=74<E8HB8(E8F
@r5346
CCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAA
+
6!A%:*B4;@7F?6#G2D3%*HG.1&.7AD5>H73,D8<$7(:C?.9/*!@&37)G#2!>+;E.FFD,(9!.#;.220E7AGD+D0!59?.
@r5347
ACATGGCGCATTGCCGCAAANTCTTTTGTGGTGATGTCTTCAANTGGAGCATCAGGCAGACCCCTCCTTATTGCTATAATTTTGCTCATGTAATTTNTGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCAT
+
%*('$$#)$+%(%+""$'&!+'!'#*%!#$&!&#"!*'"&$"#())!)*&#&"*"(*))#)%(##$#+'+%+&'&%"'%+*!)!$)#"'+!"%"&"*%(&'*))+'+&&$(!!"*&%*"#$)($%%+%+(!""&*!%!)#+$*)&%("'!'(#!"*
@r5348
GNNNGCACTNATGGNNNGNTCGGTGNTTTATNATGGCGCGGNGAATGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCANCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACNGCATTCGGCAGA
+
&&!%*#*)*%*%$#(!!)"'(#(("!+&%'%$))('(*#%(#'$)#!&"&%(*(!(+'(+!!%''$*$$+"("!'#%#'')!&$$(!#!$#"%!*$"()("#&!&))'!$%*"!#%*$&$$!#(!)$)+++"#%#(#(+!"!$&
@r5349
TTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAT
+
CH4<@E'C#")=C5;A5B'.-?2B4A@1HD<%1:2#!;?!;39G/"#<21(4&A4!H+/:)!25@G8@(C?2!5;C?+!<=@'CE+E%6;
@r5350
TTTTTGNGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAGAGCCAG
+
G;;&465A-D@;=@2C.-H7(3/"#H;<"/#.C-/+75AH"52(&F59+E<6>E*FH:"6H';<822/D0:%<+8)*)*G
@r5351
ATAACAATTGATTGAATGTAGGCAAATAAATGCATACACCATAGGTGTGGTTTANNTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTT
+
'(05B39<57H*)C9&'H1=F9-.;"&'B00606=6>=B5AF$(G:,0/,E%;D>G(G31;A*.);4880H>&@8F(<(+E?=;-&=+,E$*@(*D>.+&..
@r5352
TCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGC
+
.H+BE$$6!.#H+C4($2)GC(@B9$.'(;CD&$%D2<G8+2><G)7,
@r5353
GTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAA
+
"1*'"@6&8;"5--D+G@0FH;7$'?6.#/.:A?5@?FE,9HE7
@r5354
AGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGNATCAGCGGGGTCATTCCAGGCGCTNTCGCACTCAATNCGCCGGGCGCGGTTGCGGTATGAGCNGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAANATCCCTTACACTGGNGTGTTCAGCAAATNGTTAACGGCATCAGATGN
+
++.*$H%H5@+&8E)523?H!A:6DE)98H/#(&6!(2*+;0)968&%B<"-=@(.*)"=.B#5F.-*G84)7/<@2?=68H'(E'G%+)>?B8#H4B/E>EAD8?)@;0,$!&1.%BE*E718!8E,E31)"B):#>/$$G%A0(#07*C?(5H/BE>0?$8.89+*2<H/C&28F,-'>29D<<51!+:62H,.3;.C8@/#ECB)1<>G7*E3H)FD>A>31@E'55%-'(!54%;$
@r5355
GGTTCTGGCGTCGTTCTCNTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAANCCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTTCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTG
+
D6>126>)8H69961+35E0!$E+HFG<B.A"4C,B:1A)?0>7860!$3$7*+;>*3>'5D(#=/)0C)((BBAD>*G&)A8;.3-E2H<EE)-E<CH9?$!<GGF)5!E;-,3'6-H1#G,34?!B!0,*9:8$<->6*<*D.#2B4)/'B2,8++5321A3$6@,EC/8EDD
@r5356
NCTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGAC
+
$4;H:!?#H<<4858.?E/<$".@)D(-')(("A,&!0<<"/,D>*39="%*$C@:55%A',CG6B8'2+>5;<()A4"8)#'F*+'7',#$>)%<$&*'.)'.C1$D-.5!+H&H4),=#6CB(:1A?+BD('*@3>E1:?GG&,0#)DC5%D+B541
@r5357
TATTANTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCNAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTNGCCAGGCTTGCTGTACCATGTGCGCTGATTC
+
*2AF*!),?F)C8@A+283&HE3>)CB3?B.C72&&5A((@"/!3B03?9*9G5*G=%)7+/51.CA.)1B40H='/2CE<F5,4+6AB)(484G#;>,?30.+(*,/5=8@%&(;#@+8=/<63:%*0=*:A4E(C:34D&&33(E!9::%%7#!AD(0+)$(2?<7<:C#B*:&B)"0"%')3%=F5
@r5358
NGNATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATNTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGNGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTTTCGCCGAACG
+
!#!+))*%*"!*+"%*"$!$!**))!%%)*++*'*#$+*'$$#%!*!*&()&$!++'$*($+%#*$*&'+)))("+#'*#$!$#)'!%#*()+&(*'$(#'%#+'%)*('(&"!)'"+"('"+)"+($%%#%**$')!+*&'+%(%&)"$*'+$*+!'*+$+"$%&%)&)'$&$&($&%&#'+'('(%%"%(%$!$((%)&!'!
@r5359
TNGCGNCNCCCNNANTAANNCTTANGAGNNAANGNATNANATANNTNNNGNANNNTAGTNACNNTNNNGN
+
"!""#!###$!$!#$!!$!##"$$$$$"!""$$$$$$"#"#"$!!"!!"$!!!!""###$!"!!!!!"$#
@r5360
GGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGA
+
@"2%*?@7)0*)=$=&)&1H=4CG64B3CB-B"*H0=3,"E*1@D+".)73C>D#B657>#.5D>F)!18?&GB:)=G98=FD<G5)&A@'73;H1'9@+56$<<C*GC+D0<:<%(/)4D41@+H',,/B0>H/$H:;F/C7B!*"<
@r5361
CCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCNCTGAAAAAGGGCATCAAATTAAAC
+
;@;A@<%+)'89*B%*40%;'0<+G==*C>);0-:&C(>?-C*'5:B&*=B5-7B<(F@:)CHB++31,7?%>?F1#F,6@0FG
@r5362
GCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGT
+
@G-&8"D8<6@/?;0<%/@85:%CH#G+8F'%B7818B;BA&;H6!1C=C:C;%C90B,6)25:;-3.G65H3H82:?58-&@
@r5363
GCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGC
+
<*D%*&,8A=B2HD@?C'0E9,*'GA4?11BC7<#A02"@>@F'#%<-$G=*+9*@>9<:2C0D%??<*4<
@r5364
ACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAAC
+
/9=:5#C!A'-5*4.63,E3/"0<$C.D=A;FG8D(75F8GB?9D42+16/+H<21!0G=)
@r5365
GGTCCAAGTCTTATCCGACGGTCGGTCCTGCACGAACGTCATCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGT
+
*')(*##+$*$#')#+"+(+%'%!+&&*%&##)%'$$%+!&+%%*"##!+'&")&))')&(%*$'%#"&**+$$''++!!*'!+#()%)!++"&+&'+")$"%%!+$!"$*%$#"*+%''&%"*#(
@r5366
GTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGA
+
3,ED(H@A(2/GF3'C>8-2'EA0!(-/<BBBG29CC,@@:!78GB0%9*F>;25F)C*BH';>:9+HF6C&E?3>B!'5&1>%,E(<3?1?:H+#HAB*2/*.<4@>D5F@+*/-@=A7?,"H76:3F<//$%$9>/8G
@r5367
GCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACA
+
0%3B:*0(E'D74*#-%3.>(('GH8D9E4)F<">+!)"?G5G$4A636H*;B321;"6?9$<394"H8,H%EF'-4<7*;=?',2$:A+!H$,HF?0.>B
@r5368
CGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAA
+
C$'%;C$$=.:$=&%.*:!&))3;)A'%?)6?#E;>%0.3?0+:4#:!8C#0><'@7&@="CC/C:7@.+4?093+A7C>*<;-9194A?452=/43%B@/.'&/#5%$?6A/"=>2=&63(@D59#9H
@r5369
GNTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATA
+
*!)+!$!()))''")(&#$(!*(!)++!$"!""!#+%#%$$(+*+*#***$+*$%&$'$)'(%%&)($'&
@r5370
TTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGANCCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCNTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAGTAATTGCAACTCATTCCCCAGTAGTACTNCAAGAGGTTCCAAAATCCTGCATGT
+
0GG&7E<)2;#(&3D>-A%=4;#0=(@!D72'(G%?1/<A2F$.;=;=1'--'3G;:/*60"3,?0@5.!HG&2-!'CHH)?BGE)(F)35;=7&A.H*#3=%>-(99FG28/%3B8D-B#C(!6=<3@5#>B7=@?)D%+('#(#@HG>:$B7B%C5=A5C??"65!?9="/EF?&1.&.@=&H3)H3<E8*41:-B
@r5371
NNNANTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATNTAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATA
+
""!'++")''!$""'#')''#'%')&'+&&$(%!"+%))#!$$+$"'++#+&&%("!'()"+%!+"&&$+$!%)*!$(*+*$&$++%(#*(('$!"+$#)'"&"'"'#%!&%$'!%#*'''")(#"("$#''")%%%$+)(%!)"&&)$)"#&%$$"$#(!!+'*"(!)""(!%%+#!*%&%((##)'!+$#**+!#&"++!!(+!"%'!&%&#+")""!"!$**&)!#%"*'()%"&)""*'%%*+("$*(+'#'((())$+)&%'(""#+*(!(!)#!**!+'&+%')*%(!"+$"&+*#+#'*!%%$)"**"#'!#*%'#!#)&$#+(#(%(
@r5372
GCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGNTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCNGCAATGGCCA
+
),E,CE8&/!+C2<;9@<39%$="<:;?;:5>>@G##D,1-""C:.>">>?%CDH4>5!F;98F9:HH208D(5*'G'96!!!@3A<281?G:AE%@#HF<!29%0=97=-H"?G@6
@r5373
AGACGCGACCAGTCAACGTCTGAAAGNGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACA
+
:*).';<,36H6$&G=+)(&B;H!(H&CE5G.0)9.5;C-?@6'A)@-D")BE=#H42;E>'?*5)7
@r5374
AGATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTNAGGTGTTTTAACTCGTGGGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCCCCAC
+
$)+*$!&&+%*"&"''"&($!&(+!'!))$%(""!&$+*'(*(+&!!")!(+((&"+(!*!&%&))"(')+#$$!""+"('()+'&"$'#&%*(#("+
@r5375
CGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACNGACAACGGATAACGGTAAGCAGAACTCCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTT
+
'!?/C=>E9D-(6.<"A.H0+/9//8@"9/=:E//&9++:8-B(80E.6&=H@;35E)-H-E:=+,))G43*-GG6!A<$?5E$'7GA'=@<6<97##C1%%0)D?0-.4
@r5376
TTNTNTNNNNNAGCNGGTNNNNCTTNCCCTCCGTGGTCACANNNANNNT
+
$"!#"$"""!""$!""$""!!!!$!"!$"!"$#$#!$$#!"!!!!!"#$
@r5377
CCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATA
+
H<4@0:?&1&)5#:;92..(*3C;(9&/38%2C4>'0,1E:+48#=:'$F/-"3EE?9.=D3"?C37&*F!::HCA3H3,->!
@r5378
NCGGNANNTTTAAACCGGCATACAGCAACAACATGGGCTGGTGTCTGTGGGATATGCTGACCCATCNNCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATNAATGGGCGCTGTATGTCATCGGCCAGTCCTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCAC
+
&('$$###'+#%+())&#)*%"%)+)"*''!*$'!(&$#!&)")+'+&((''+(#"+%))!'#"&$)(%(*"(('&*$''"+'+&*$*#*)+"'+%#%")%&+$$%&)$&*'"+&!)&*%!$"+"#+)!(#*(!&+''%''#($!#$&*((*'*()*'!)*$+'#$"!!#!%'((
@r5379
NGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATNTTCAGTGAAAAAA
+
%=E,4=$0/2,*68>6?:G0/4E%>9#A7#--A1C9++,<@90""%8?.%>;"++E=,E,,.9
@r5380
GGCNANNAGGNCACTCAATATCAGGTGCAGTTGATGTATCAACACGGT
+
&$%''&$&'*%#)#&+*''&*#"!'!#"$"$+*%"+%(&#!)&*+'%$
@r5381
CACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTC
+
3;56.1,1.E&43?8&?5A-&151-A7)H276H2/??.@>).B!'?*H36H'G)((:C.
@r5382
TAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTA
+
")+$*%**#'+)'!&(*%)%+"*#)$)%$!*&$###(*!&'*'
@r5383
GTCGTGAAAGAAAAGAAGTGAGCTGCNTCGTTTAACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGNTTTGCTCTGGATTGCGAGGNTTTGTGCTTCT
+
+4;0,6*<><)6F7EB.&-2<@C7'$8D<<F+1H-"9/E/D+0#"7$!0!A)57E,@C9;!$G%9%D,/1C*62(BCF29%G1),0G1D8G+28%5$,,(!FE&:!.$6"B"7:!G?;>28
@r5384
CGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGNATGGGGGGCAGCCATTGGGGCCGG
+
&)&A9CAG4C@29:=37,'E5#)/DC6.?,&>$8<A0,@++"H,/,6$2A-?0)(&)%G#?-A$/!+=E
@r5385
TAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGA
+
&0+74"1&B-$>8#;==E:>$ADFB:#CG;%5E*-G:@6A=),
@r5386
ANANGCGACAGCAAGTTNTGGNTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCT
+
)!&$+%&+*%!!&"%!!#)('(+$)+$)&(+)&!)#%$)"*$''#$*"&'"*#&&+$"&*#"#'&+"*+!$*$&*"'+!))"
@r5387
AATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCNCCGCCATTATATCTGNCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGC
+
1'37">(G2D##C22799-)-BGC=2#62:8(*,H5<@@C/-79:.FD*+F$5'6((;@AE-;360A7">1(HB!*,>.476(A#.H>1:CB8&%%);$,8E:2G$*AB&<)326@CG5$,5CC*1.A$),:676;9GBA7@5EA"GC'.+"&<6#>7C'A/DF)(,A34&EG6HC"?(,5FD';1=4<"C1@(.4F?=>
@r5388
CGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCA
+
H8H>E"4H+!9C6C3/-24@.76"D>''HH<#H4%/@=(B9#H*>C.=$.CB)
@r5389
ACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGGATTAGCGCAAGGTG
+
B0H>D.+?13A.?$2'3F*(,8>>GC$B1@=**,#!DE-'%A?7@40B*G%'84*F+G41
@r5390
TGNNCGTTTTCATACATAAANTCCTGCAGGTNCCCTGCGTC
+
(&$'&&%+*!$("!%!%&**(*))&#$$+&!%$"!)!%!')
@r5391
GNAAACNTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCNTCCGCGATATCGCAGTCGGCGTCACAGGNTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCNGAAAAGGGCCACGGTCAAAAATCCGCAGCCCAGAATCAAAGTTAACCGGGGGGANTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTNAAAAGGGGCAGC
+
%#&&)!!&'%*($))++'!)"*!$)#&)%$)()+'##!('#""##&&$!()&&'%&%)*!%+*'$$(#+(%!')""$()'$+*$+(%"++'+$%&%$#(("&!'+*)%("#)"$)!'$((*()%")'%*)"&+*&(!('+!)"$#(%*"%(#$)))"+"%+#&)++%%'&*""(!+&!('%'$'++$&$!+%$+$&#+*'$%((&&$$")&%"&('#+&+$!+&%(&(!$$'*#**%&*+**%"$'!)"$')#&"#"$$"&+####*#&*)##+)"$
@r5392
CTTGCTGNGGTNAAGNCCAACATTNCNATTNNNTCNGNTAATGGAGNGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGA
+
")*&$%&"##%!$)#!"$'&)*"$$)!#%)(!$&%!!!))*(%)'*"+)$$$*$$)($"%#''$%&$('&"*&*"+!)'!*%"!$!"+)%)*'
@r5393
NNNNCTNCGNNTNNGNGGAGNTGNTNTNTNTTNANGNNNTCNACNCNTGANCNNNCGNANNNGNNTCNNCANATTGGTGGTTTNNCNNAATNNGNNCNNNNNNANNCNTCNCANNTNANNNNCTNNGGCNTNNAANNNNNAANCCNNGCNNNANGCNCNTNNNNAACGGCNGNAAGGGGAANNANATNNGANCGNGCNN
+
#!"$"#!"#$"$""$###!"""!!"##!$"#"!$!"!"#$##!##$!#!#"$!#$#$!#!"!"$!$$!!#$##$$##!"$#$#!$$#$!#!#"#"#"$"#$#$$"!$!##"##!"$!$"!"!!#""$#$!##$"!!$"#!$##"$"$"$$""""$"!"!!"$#"$"$"""$$#$#!!##$!"!""$$$!#$#!"!!"#!
@r5394
TTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATTCGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACCCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGG
+
,$)01>1>77&G&=?2#*,&4)@>(3'4('G"?3?A!3'@7;<A<",D"9-B&66D5!?+C<0/86$+30*47D*/1FD./$@"F7+?#A>D*85%#FE43-#BH+9D8-?#@<6%G&(=D+/G;>>3-#>>#!0@?F@FC54!><762=8=3'>:17#@C:/>B#!1C+>;);A'B4:>$$08/E-%',%>1A?H9)$
@r5395
GACTGTGAGNCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGGCATCACGCTNACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCNTCCCCGGGCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAGCGGTACTTCNCGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGT
+
DE$$9A$,16A"*94&>0F&*)58H8F=>?'.?)+G(5*B7G>+G'./F,?E"A5%%5G)!<*D11(A'2AE6.E8691-B")+1>11C17D);7+&'"C+3<1&!:19<E#8G<8.3E3&#:6<?CHHEF2'FB02(A185')FD,0+C%(5=4B55H/8*!2D&&'H92/67>,@>?=0.2,F-$"EA(1:)#6?:--$+A((&CBC(+;?D#,3C3*H4FD?-7@DGA3/@&)5<ACF-49$!'.!H9F$'B4(%,=9#!H/AG5'99>!."#B.H8B.5!960/>?,F"GD.9
@r5396
TACTGCACCATTCAGCTGAAAGCCAGACGTNACAGCACCACGGTNGTAGTGAACAC
+
",GA&8$-=("<<=5G2".E!>%G?5E-8!E0'A?>*0&5>D<?;=1?5BC)(1=,
@r5397
ATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCA
+
)8$>C&=67!&$6'5+:"G:;HD5!'+'E;')E###35#55>H&1''5+#9D)7+,/581',=(<8??>F-H8;2=";C40*,H&.
@r5398
NGGTTCTAAAACNNCTNNNCNNCGNGNGCNTCTTTNNNANNANNNCGGNAACGAN
+
"$#$"#$#!$""!#$""#!"!"$$"##"$!$$$###!#!##"!!!!$$"!#$!$$
@r5399
GCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATA
+
*2==-$;C.",)A5B15*0>>$.-F9/$,,$%,&881'2B0@?&@BAE,2E>$!E"@>F64%3>0&+952F0H;6""@8.E
@r5400
ACATGGTACGAGCTAAAAGATTCGATACCGGCTTTTGTTCGGAGTCATGCGAAATACTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCNGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACANAATCTGCGAATACTGCAAATACCT
+
+AB*G)5=2H3&9D.!8-@*6&E*FC&D>?>4?!/3C9-3B/G/<-6#!0>*18,EA@>D$-''9B'97A;>+@*"H484F9,#:&.F9*G+:D>4<&><4=.7B'(#%5"E9;6%/.4.AD==H2#+G#59@7C#51,8E>9F39)EHA<F4D)'?57%%E-61CC6-6(/<8F4%)5"7;E>'+5%)3H(5?27#D%-C".;*F03''BD'H"""=,?@08;??+6&9!D;A!*-,/4=.&4;;!*0/)96(:*/!5/4*G%='-#B.3G/A.09/7:89=>5.5/#1C&2
@r5401
NNATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCAC
+
"!EG0#=(+96()<A(A5+"FH4:!:/GH@H;13'?46*H(<2+C$4'4/"/
@r5402
CNGGATACCAGTTCGTCGCGGCTTTTCCGGACCCAGNTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTG
+
%!0!(<#(!?2!0=4&@6<<74;<#!:*=!D,0H=1>'0'-5%"DH!C8(49(>/-D2&4+B)#,G2E+C&+D+)+,1@>AF(0E26+A,/+-*F02HG+CCB'32'&*
@r5403
GGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAAT
+
4G+15E"B@F89++$6=5?@=3?B88G@2:(5+!H;!+*=47">+/"=%(3+:$G0;6969E:(/>0#,</;"?2#&
@r5404
CCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTT
+
833;=#9.$8<:2?.FD(90>=G20#>12%!-'?:417?9'12A=<65)$HB;&*8,(E822G(/)</&*B-E66B5A7:20)9F::;E7(C=#,5</H+3.G8<=C@!1E2F/-??F<H29&-!$/$,94<$:
@r5405
GNGCTCTCTTCCCACGCACTCCAGCCGGACTTCAGGCCTGCCATCCAGNTCCCGCGNAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCNGCGGATTATCGCC
+
*(;C=+7:GC9"#@0+#AE5>8G("@AF!71(*>'@C&E7!(,GB7?G!;-D?<$<8@%H&;()E2*%=6-%1G*4-ED&C,EFH*G27F+%/7G!-?9@$6"10<==-$3DEG#%.7C5,C6+;%56
@r5406
TAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAAC
+
4D.:+2>3G12=?'1'70!23;?)A<&(=64D<6=,%2F%*B$F/%&4)%
@r5407
NGAATTCCNANNAGATGAGNCACTCCACGCCNCGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGT
+
&&#)'(#$$#%"&$**(($&()%#"(%'"!'+('*)'!#'$)#($+%#&#$%$*%+#$"!$!"*"#&+)"+&)*)*(!(*')"#$
@r5408
CACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACNTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGAGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCAN
+
74$@9$4&7',<?.B;$B=89,*<3@;($5"?.;5@23'26**//+E:@)F,G;(=@=@<)6B"'@EC(2)6F4F"&B(12'A@*D76%<'GF>8/1@5"0)5?F5D>9/8?6*9-G>7(8-1(*&3G25%<GE>FD)87<8;.<?4/2C;$.(%"44B2<F#/E32BAE"(6"2..1;69G;8'?8'B63@."*9(C";'>GCBA@3%GFG(!(+4!?5*;%47>A-1>D73C3:A;6B+-(!#.
@r5409
GACGCGNANNNGCTTGCAGACGTTGTCTGGTCGCGTCNGGCAAAAGTTAAAGACCTGACGCCCGGNGAACTGACCGCTGAGTCCTATGACGACAGCTATTTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGNCGGAGATACCAGCTTCACGCTGGCG
+
!$"*&)$&"*"(+*+&&$"(!*"%')+%""!$+"'")"+(#(&!&'!!"$$)$%$%$"$(+$((+++&+!!))%$)(!$$'*!$*)*&'*("(#!'")(&$+('+"*%%))%%'"!!(((&(!')*%')'&')#!&*('!)#)$")!%'"&$#)!&++"'*)%!"'+)!%()#$"%##+!"
@r5410
TGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGA
+
89=*C-?,56<1)&6'E:@";@0H.;.(.G/H'8G#%<%<G"2/8545.'C8)D&75"-@*)
@r5411
GCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATNTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCACGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCNCAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAAT
+
.)"2!-83*13G/'2:2)#42E02!A4"D@(0E<DA')4;3>*(5DF2H?7H!2":>+*(B719,D/737"G+!/.*9.A7&!*3H4BAD;#-A"A;;<5A@-716"'B&:,4>F=G?5+E>9"$,@'?=E&5<2635B4?E%)9==A?DD*A.D?/)+2<'4@&B?"!1-C=!&6H$D"17'/@37?7&B;H)C8@@#==462E'#)+$D06/570:.#.&*0!7"DA32..%H&4"@9.=?.4$=)!89A-4@-8F&4,5#97<1'$974>99$A3#D@48DE:/C79$.GAG&<%E;8A8$-F=%;;875F-5C?(C(@+C7>)<+@+7&%>A1B7,67%)@$4EG3$'(!#'$A23/2(E(5EA;98)6@7?!-%F6*?:.;>4&$@C#*C)?5?-+@9"<9,=
@r5412
TTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTA
+
4:*/*&E!;1AD/A.%49;%.FE-*71*8B+3B)2#11-1<0'B>)650#?/3
@r5413
AAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTNATGGTGCCGGCNTGCGATGGTGGAAAACCGTCAACCTGCAGAATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTNTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCANGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAANTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCA
+
0)!0><B.C->H@3?!>+7&:E2'8H85(,16F3A0.'&@B%)/47BC:G$*A?4:(5,+6A=,CG*(7FDB--CH%=:/B;'<,H07>9928;1'02/=:0!!6%;GCC#<&,"1/9)(?D!<*!*#5@F(00$<9>34;8@;B#,-"39GE9AG'@@G""B)C9&E!412/;4@/&-($D7#610DE<697EE?EC&$:42.=<'8)!)+4D#>%)4.H@+@"-?&AH;=-5%"F5/D?/=2*E03%'*1!E5?1.6G"HH,=56<*E83/1G-4/G5A?7<;:;'>5HF,7<B7+;?EF3;*C%>(2BA2."AH%E-3)5?/D6D6A5%$4,%828(?CG&1.$0*6@D'6'=3G@%+CFH::&;8>3A;"H(E'E'#4@D-0$7+!F'&"--
@r5414
ANCTGTTTCCGTTGACGAAGTTCACCGCNTCCAGAAAACGGGCGTAAACCTTACGCCGG
+
*"%(#+$#(+*)&(#$(&#+#+('!"""(*&$+'($&!!'*#)'#$"$+"$)#"&$%''
@r5415
AAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATNACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAANACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTGGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGAT
+
5"6D!@2D'4;$A?2-G,*!=,%;..)-7;-.3>'4"7(0#9$#>3,%30<F,>.-F#$CA%,#1!C/F&%*#"/(.497GBH?350C#0:3@#B<7>#),?%&!C9CA/=:-2%7HF8/8@"7@E+E*5G+"2='6B;2&*!/1%=B;('=F'3F$'.:AF2,6BBB@#.7C!&A=5.3,(9!G+#+&DD%F&<;0=E@HFF"A)H!6"2@3>:H)8<FD?@+))A.1:=*(-<))(A2#/A>DBE24<%6:E$%/!#?6''!G@BA3*3A#)>
@r5416
GCTTAANAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTNTTCCCTGGTGGTTGAC
+
E"1/#3EED100"F392:=1&E7?138$@7&-.+<%<$>/&4%$13#"H89"<*7/*99%<?)005=<65;6:0/%$,@:D$0G<!C'#/;E,G5+!<,&8--,+.746*>5H==5F8!:4)!(F71@:$%H2<,;7'H<A6*:4
@r5417
AGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTC
+
489G1=;:#:-:=52<5&$<-?-7H=C3#@1>-)0E+;,GFE$6/B6/GBG.$?%&$31;27%#BFD>C38+#9:%0-E>=3;HC3G48$70>.?!/9;FB9+91GA?.-$?B*>A;:H*-%2!D-3F=6H3"H"(@/9.A:(&=)?A#D#G'H3-,8+/9C7?6DC;>EAE"4<H+00*+73A6D684+.*6,.+)1G#7?A:7!,#C7
@r5418
TCGGACACCATGGNATCACAGTATCGTGATGACAGAGNCAGGGAGTT
+
/6?='(@=CF/AE*?").<%+:*?B9/3(54:9GAB.&#F'!GG=B'
@r5419
AATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAG
+
7H;A#F.,'*HC1"%8?(;6%0EE1&@2</FF933G=<-F7HG2(D;&8.<GA!)?$-(C8:2;&5#'$3F1B-%91",4)8(!>G)A(D<2CGAH$A6BD'"!<(B%:
@r5420
ACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATG
+
85!#H#4<!0B.&.8(89D,0>=;H4DF.C&D?!#7D:C3A>@)2#4B8;3?;,65-4/)B29::7+40F?%.<+A/%<@#,7.=/D).HE?05,9*%G!,G-H*E/5C(.944AAFE#E&'8?63F%2,2>)(>4<#>=3!@*$,(*71-9@92:64A>C>4@G&!.+!,@-;"H0G,84A$9GD'F?E&69.&?0=A*<@820DFF)*)7;3DD0%C')
@r5421
TGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCAT
+
C6!B:"@F'-?D>*#!*5/9G5",++'%'<.$<#(%;@G"$@<'
@r5422
GCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGC
+
3A&.H0=)"?=-A?7!4HC$4("?5/D1%B,:>AG*#*@0);65)2<91*-
@r5423
TGTAAAATCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGT
+
;2"9%6>3(;G87C?<?,:3$8:.0B%,$=365C?42/C.7#1>+!#=.F2(E5B6+.54>$.2-5D!1F193)(-59%,:?:F",?2&7
@r5424
NATAGATCNCNNAAACANAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTNAAACGNT
+
!*"&#'))$%!%&))!+')'"*#$)#+#$%((+(!$!#'#*+'+)''&"$!'%+#+$'+(#&&
@r5425
CGTTGCTTTCCAGTTTAGCAATGCGCTTACTCCCNNCCGAGATAACACC
+
"E&'755.6.#1/C(=+@26@4*/%F<=.!(!%D8)@+)71$=#?5<$-
@r5426
TTATCGACATATTTCCCATCTTCCATTANACGAAACATTTCTTCAGGCTTAACCATGCATTCC
+
&7%+@@1E0=>H&1)69+#>=G$8!H$5')6#:DCH#%6'G358<*#!;=5+:?'((0"7"$H
@r5427
GTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAA
+
',=4'+E!:CD#*)4D:,#/3$0G-=7,:.26CA%;*8AD3;;C%785+A:,F,@&4@0.G;B
@r5428
CATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCAT
+
70,BBE&#(243>,)F&/F,C3E?(5<*8-81D-<*E=6210?9"?:3B)?
@r5429
GNCAAGTGCATNTCAAGCAGAACATCATGAAAATAATGGGTACT
+
'$%$")#"%(%!)+%&!''%'+$)*!&!&"%(&'+%#+#&%!&+
@r5430
TCATCCAGCGCGGCNGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCNACATGTCG
+
1!5H7+4!7>00H#4A&90,:##$DA=+>B2;?"?-3"C9/"'EGB4$E1/!.:D-/8";(@$G;
@r5431
CTGCGNGCCTGTCGTGGTCCGTCATCATCACCGGATAATG
+
6E)-D&A.#%23=;F42%2*E(3(/!<4%(?:=9%869H0
@r5432
AGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCNTGGAGGACACGGAGGAAGGCAA
+
H6B&5=7F24#GH+H/2E97(=?EG=A<G!*:A)=0G45A)3;HA5$H"CA79+?G7"',84&A#"%-!$B2(>F;H%'7?.=7832C>D(:=?";.35D'9A$)B8EEB07GAB-F&$)31&7FE,4(88H!7E:'%118:C
@r5433
CCTTATTTNTACATAACGAAAAACGCCTCGAGTGAAGCGTTATAGGTATGC
+
EC!0#E/=H0"<@*#92B525HH-D,3:9;'(E+@#,'-E19!#DDC*>+4
@r5434
TTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTT
+
>A'?=;4!%@@5$26G#8&+>6?!")%"9#,!7$524'&,83/.7,=4+63C:+A$0BH2'?)
@r5435
AATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAT
+
!9!4<.&5(0%2!?/?!4,&@33-B*G#'6D%7@8-344(7,EGG%**5*1HEF):5+-'92;%+<-*;8H-@,B8;;A7;(6FH48;('A<C>0#E1+@/*-/A,7;1C098C63D5!?9CA3#++4&>F+2/H.9#2/"2B3567A!4+C43")!!9@-'>C.B#!,H/<<8>&)A>HF%'G,+-=%)A/(=/,!;(C(@&9,C63?%!?&7@$,3
@r5436
CAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCC
+
($(!+()"*++$"%+(#!*)"!&'")%%&(*)(!*"$"'!%"(')(%*(+"!*&&("%&"+(#$()$(##'"(+#)+)*"%####!*%"#
@r5437
TGCATCAACTTAACGTAAAAACAAATTCANACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGC
+
1-/)A-,-=0<3/<%C%,9#A"7E"(?"+>4,%//"$F4<12G.%<(!68>H0++=3#@=E$.-8/@@!;%--'2./1,)8!5!!7!81))F4BD82B=9,H1.A0E#5#9;E%F3
@r5438
CCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATNCCCCGG
+
(0%F38"5EB.,@=3+*;#*=!AH-94-H,,*++90&+=95,-!38%"&:21@G$.6;'<D>)A7F9/A@82F,5D.8910B4G)";7BA#3-H7<E#G+F=:*0".D#"G;@0+?;+%57(*$#$)C755/
@r5439
ANGCATACAGANGNACTTCACGCCACGCGGGATGAACCTGTGGC
+
#"(*')"*%%)!*!%")+&+%%$**'&)$!!#*)$('($)+$%#
@r5440
CGGACGCGTTACGCGCCACCTCTTCCACGATCAGTTCAAGACGACGCANCACCTCCGGCCGGGCATC
+
4A%C=G/("9*5:<E(#-0C3;)'7<43:08=1B6%,7*/'6H:4%DFE-3C)AE5,2+-&30@&(4
@r5441
CAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAAT
+
5&1?''8;$B".5C"0F<HB;G?HD="+-,E,A></G/"$#:(
@r5442
TCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATNCTTAATNAGCCAGGAGTCCCAAAGAATGGATCAAACACTTNTGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTT
+
E1<C3?,8-481)/:D:0!#:5#%:FF/@-/=&@7(&:07HC9G0,/:%$8>(A;+'=>,">9D107<6</F'A$)13@63BDC)84CF?(,G,E/,C#-(;<;':)(>1*64H<2"807>G4G)@B$16",6(&:=)+(F-;E1."4<>B-.&%$$"-A4#F
@r5443
CAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGCG
+
@613%,G465*,-1EGCH2>,G'')D*7D+:?)6.2-;+"BGA!%14EB>:AC,A$&8;)8"CCHA"B%50+@(+'"/2C(D&(H%<,*H3.9&@%48?/99/%G=1H*+EF<:;#FCE%A3'/1A"&"AB52C=44>H!,")&"?1%4C09)?E>DD7E?;'
@r5444
GACTGGGGATTTGACGCAGACCTTTTCCATNAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAG
+
<?81#;%8@$/7-<G$<,/&B!12-H86/D5H:.&&1/#6*9,7G6+42)56;!!.G$&'D"C<4+=5H9:53,B05#7G$#3F<:7C&%./'<?%1B(9'E!-(>.),5(/8(4"(92)C("548D.FH%H@6$;
@r5445
GCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCATGAA
+
E@!?/8'2=B(FH#FGFD,9E;?F+;(!B13724E4!$D.6DEE:@:*!AA6F
@r5446
CAATCCTCCGGCCCTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCNGTGGCAGTGTGAATGCGAACTCCGGGACGCCNAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAA
+
,@AB%/5.1HB3#>D;:FCH=.<@3%B;%:3!1%!($,%+,6@)/'D4$F&@?2/1D)H;)'?)*A?84*=+'2@#%52(E)2E.F5+A>D(F#B9G78A="=/%&;*->.;G?@5-=B&991(=G39&9$-1*<#03;,1?;A/?;8@@A1
@r5447
GTAAACGCACCGCCATTATATCTCCCGCGAAGGTACGCCATTGCAAANGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTANCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATNACTGATAGAACAAATCCAGGCTACTGTNTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAA
+
+!!'!(""&*+#'$(&!$)&%(##!!#(%++%!!#'(%$%(+)#'+&'&#!++!#"**"$)!%)(&&#+$&"&&$+$%#!&$''(!$+&#*&!&!+%'#)$''!'+$$'(*'&)""$""($++'$'!))(##)#)!!&("+''))*('#&#((&++'"%"+$("%"(((!+$*'##(&*!$!)'+*#'*&('!*+)!+!#%&'(+!&%%##**+"%)'+%$%'%(*#!)%#'!)#($')&"#**#!&(%#"%#%+!"!!+'!"+"(!'(#!&#++*&(&("#(#%"!$&!%(+*!"!$**+%%%)'%$#
@r5448
NAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTATG
+
662D*2!-+*>($7??'(,+7'C,-3!G<,:-1#=-+?*9&56*7=9G,F&C2
@r5449
CACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATGCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGNACTGCTGGCAGAAACCCC
+
(+C>;$7H!@@3E84.?4.3BB=4+3@@@13B!:-+7C<#0+(-2,EF+3(HEB:!GE(%B.!=B%-EB<7*!)B'62@(+52.%!-2(8%>C,'#6F@
@r5450
NTNCTTNCTCGTTGNTGCACCATCCNCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGAT
+
""!%(#"!($$#**!+#)+(($&++)'*(")'*)!#%)$*#+&%!!%)'"&('#&"")(&"')$&*$$"%'%&*+!%%%$(')"
@r5451
CGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTNCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATT
+
!1#>282HA>0:)&42,(?C4F:%(-4732<@)H'?&/E5G;+3!&E'>>&3B7G3C=+&+'6@0.%62+&G#A)!G$AE"@C2;E)/)4B@<2!(:A=@;%@)""@34'#2;B0D/AF,4('($>C-B8FE&,4.
@r5452
NGTTGNTATTCNCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTGNCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAA
+
))*&*!('*&%$)+)''*$%$)*+#)$"'&(!*%&%)&++%**&$'()%%**!!#"&"'#'"**!$(%"&#"$)&%$+!)%+%$%!!*!)&(+$*###&("$'%+'%#"'&*!%"!%(&(*#')#*#$%$+)!*$"&("(+'&'(&#'$)#&%)#(#%&!++'&
@r5453
AAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAG
+
-D;1E-29F-(/+E-$:G16;9;%>;4+*<F)=<$@8/<">&$1..,#0,/+C++0+0EC8@4=F&%+0.9G?>+>#!2>B?9*536'$'&F>7?;(7,(4A1D1089*H1"**8+3B2D3?8G5./*1+:$@/,,
@r5454
ATCTCGCTTATATAACGAGCGTGTTTATCGGCNACATCGGTACTGACTCGATTGGTNCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATA
+
<?.7+2,$!!9(G2&G;0E<73F:C@(C@.E)5E9(*>,E%*9+$"'>?57$&768;5)9BDFD10+#%D049#?)=-@=,*8+G6?%>G6$%E)?(%'+G:;"@CE+@H-1&HB
@r5455
AGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTG
+
9<3;#)2,;.B83BD('-)-H=G3(G2?'9C0,0!/320)53'+<-
@r5456
CCACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGNACAATCAAGGGGAAACCCGCCAGCGGT
+
%'+*'"+(+!*&'"#&)"+%*!!('!!)#!&%%)#+)*'%!)$*%$(!($#&$**(%%%#'#%*'%'*")&%')+('&'*($+%!
@r5457
CAAATNANAAATCNCCCTCACACTGGAGGGCAAAGAAGATTTCCAANAATCAGAACAAGTCGGCNCNTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCACTNTTTATTCTGTTATTTATGCCAAAAACAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTNTAC
+
###&$!*#$+%+#&&+++"##)%((+'+#*&$&++!'))$*%%#+"*)$%'$!'()$&)'"&(%&%!#+"$*!&)((*)$&+(**$)'*)+&#%&%+(''+"+!%"%""")(($"%(&)&#%+(%'#)%+()$$+%$#""%"%***"##))$$+*))"(#*+')('$$$"*$$'%(#!+'*'&+$**+#('*
@r5458
ACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTG
+
/";"%9/9H117'($)44)-7?E8F@D&(?0F360>39<;#,-9(&/:D#"G5C-#6H=':6E(&A@8&,H+$C,#4%D*;8/%G-14EH
@r5459
GGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAG
+
<C/#5A;C5,(28-H,49"##B$D<,.624:5@2C!C?8=/CB(17$?5AF&>*;5".D;71
@r5460
GAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACNGTGTTGATACATCAACTNCACCTGNTATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTAT
+
00#"&G/,H+%<F?%71;A9;4=G8+/%F"2;8>(->37+9(=-7>7%67&ECA@;1-#2:@7E;<;B<F#<DH2!<H-">)23A9@;*1@5$,2&9?!DG)5=H'(7A+D"C?-';D.>D(FCC?-=>!D43#>2-CE1@F?*4+1:0%#!5AB1(&:&16@=2209
@r5461
TNNNNACCGACTCATTTGANCATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCNGA
+
#$&%++*("')'$+&*$#!+'$$)'$*"#%''&""*!#''*&((&*%""!&!%'%$&'()$$((+'($*)##!)'!&"')+$%!*%"$'(%*)*+*+++')#'**!$'''*&
@r5462
ACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCAC
+
=B<FA(751G0060>?2E??'<$')3#8#",759#B2>8.-8HE-=39&5H/AH!9%3!C>)/1
@r5463
CTACAGANANNANGNCTGTANNANNNAGGTNGNNNNNTTCTNNCAGNTNCNANTNNANCNNCNTNGNATAANNNNANTCANNTGNAANNTNAGANTNCANAANNNCNNNNNNGCNGNNCNTATACTCNCNNTTNANTTNAGTNGGNATNNTCNNAGNANNGGTNNTANNATTANGCTNCNGNNCNGTNATNNNNTNACCCGTNTATTNGNTNTNGNNAATGNNAGAANGCNAGNNCGCTNNANCTNNNCNTNANNCGGNAAACTNGATNNNNCCCNNNCCNANNANCNTNNCGTNCNCNCGGANTGNNNCNGCGANGATNNNCGTGCNAGTGNTNNTGGNGNNTNNGAATAGNNAGNGTCNGCGCNNCCNTGNNTNTTGNGNNANNTNGTTNNTNCNAGAGNNAGTAGATNAGNNAANNTTNNACGANTGNCNNTNNCNNNNTCCTGAGNNNA
+
"$#""$#$"#!"!!##$#"##!$$#"##!##$!!!!$#$$"!!"$!"#!$!$!##$""$##$!!!"##!$$#"$$$!!$#!$"$!$"##"!$#$!!$$$!$$##!$#$!""#"$"$#"#"#"#$$$!#!!"#!"#"#"!##$$##"!#"$$!#!!!!#$!!$$$!!#!$$#!$#$"$"!$!""""#"!$!#!!"$!$##"""#"##"#$"$"""##"$#!$#!""$"#$$!"$!#"###!#!"!$""$$$#!$$!$$$#"#$$$"$#$"#!"$##!!!!###!!"!!!!#"##"##!#!#!#$"$!$!!#!"$#!$$"$"!!$"!##!""""$!!$#"!"$"##!""$"$""!""#$!""!$$"!"!"#$$!!!$##$#!"!#!##"$$"#!#"!"!"#!$!!$$$$!###$"$!!##!$$"$"##$#$###""$$$#!##$#!#$"#""#""
@r5464
TATNNNCGANCTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGAAATTATTCATTACCTNGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCNAAAATGGCNCGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGG
+
##$'%'*)$!#(''+))#+&*!&*(&*"%%')(*$'*%'#)%'#)!$("))&'$%#""%(&'*)+'+**()(*!"&(&))""!+(&#)%#!$)!&&$'')"!*!+)!*$()*(&#!*''$#!"')(&+(!!'%%'&'#'*'(*("*+#')')$*#)%++'**$&$*#%)&$#(+)$&&#++)"$%'(+((*#*!'#+++($(+$()(('"'"*&$+%)*(%#%*%'!(!'&""("'(#"*$))(++!##%'#&**+$$+
@r5465
CTCCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGG
+
1@:5D:):19(:C+"H&C"47)88;C*1AED;<9'#<?CF+;!#&+1F(B#=4?7B'7'57>G6&<$(BF0';5!3-C@
@r5466
ATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGNCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAC
+
+:5F5+A1+E5)-C&?'2:'F"47*"/E(0F8&:@79H!B0BD56D&3H7@-.;%:C<,)2#G5H<DH!/E019(*G&@:!$&3(D,GG,''@AH90<)F%;-()289A"66%3,8,'1H1<-:D7@<-,B;!A!DAE*C/</7;&)H2+*8/;<=#C/)3/&$&7H3C8G;D/4"D?B>(-:D+DEA@?&*"2,'+(+++;BB7F,#B47;/-:*(460H'/364D#@1D;6$%46,-4?B%0"6@',?>'F)"F/7-@1EF$,=DH>?-?"84(/.7
@r5467
CCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAACTCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTT
+
778087(8#;/+#AD:A)=&:3/.$@=HFC"D$7A?1;.9558#8E0*+G5@B&!9C%!55D'(A2?&1<7&"%4<D:-&'DB4AH/F%-9:@+'H$1$E6%5E5=@;=.(<3/0H.-3A)4!F6E=E8"A,G2-#+H9=*=;E1:@$=
@r5468
TTGCTCAAATNCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACA
+
%:$4D3<9H=6E4E==A>/,'-9/(?A55(3(F/&>,D/7=*F1+5;/4E&B/3E,:/,@GC'A%H>$31"=4B"7051A'0&,$93;&%$</-#BEG'!AF)*)/007
@r5469
CCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGANTCAGCGNTAAAGGTTGACTNAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATAGGAAGAAGGCGAAGTCATGAGCGC
+
5.!E=?4@69E7"@FB(/:&B9(-?63.1'<,/BCE=/6)53?H#3=BG1<&)4H1B:CEB5,4*H#-0G5!%<2(#>%#,3@H>7F<94;*(.$16&):F"8)*;'9?1H#!C;3B$*#.;.3
@r5470
GNCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGG
+
("@@*F'<12G5;5+?.!>"8+*?,"<6;'GD3C$<$9,<'
@r5471
ACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGANAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTNCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATACGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCNTGGNGTTATTCCCGATGCTTTTTGA
+
DA9H/)BD<'2D5#E-=B5@H4$A?0>+2!660$3:C>D4060&+(HE,C/?&D8.8B777DG:=H&:@?=2=6)5"C>B+&(,'(1<"1GA9%!G":<4B!.)+24+F9.0C8D965-7-:&).0540<-6:@)*20,GB8B&:5(G3+()7C<+:>)BG'F*,*4E(04EE80,CH*>(%$F:9.1*B@%'.G6;@;;$)">H>A=G23#>.+9D,
@r5472
ATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGC
+
>G*C=!("H!"1!B-14:>$+?,3DF)F(G02=2$?25>F;;>?0.;,8!=**.%CB.+-"#*$CAG4'=")$E=8-
@r5473
TCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCG
+
-C.B9CA?4//58H-,,,#BH;,G9!<02F*FB:++'422>A:%;/1*E=H?2+2*1E:8@-8/>;4895*5C"H511<HG!@:=4@D*$*17B<7?!:/25/8
@r5474
TNGCGNGNAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAG
+
*"('"%&'*+%%&")($(&$*%!"+!)')!'('%!(*#(!$+*(*(&#")''%*
@r5475
AATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGNCGAAG
+
<GB*(&)5)*>+$,D1B!*3#-H%A!H76D,68%!;D-HG=$4#(-@75@8?(@(:0B?G##/#>3
@r5476
NCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCANCCTACCCAAAA
+
$'$-F7%3@F:9"%#$E9;';(=A?3/D.GD;$(>0>$(8%7H.:=E(#EG1&+A8@9,(5A"7&H7AA,',7(+:9?.E3G$,0<";)=,;14F#*.%?C-)<@D!"0$391030@F*=$:#)G859;&9.)D"!-DD@*!3+41+6:H617&5?/&81#!8&$D7)E<C5F&?$#2&/604@F7
@r5477
CAGAATCTCTATCTNGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGNCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAANTGATAATGATTATCATCTNCAT
+
D.A"528B'@7D45+9C78@0>G#.$?%,A;!'+A;@$.>%4&;5>"5>>(B!=E2AA7C*9;>31)F/-5FF:BD3*@>A$$<D$.:AE!1%B0:.G"$0)$D65)02./4!1#HA%2%7<8:31H.5!H++B$8=F3
@r5478
NANANANTCCNNATACGGGGCAACCTCATGTCAACGANGAACAGAACCCGCAGAACA
+
$(%!($!"*")%+('+&)!$"+#$!*&&&*&$#*+")""'#(+!$#&'*$+*"(*(&
@r5479
ACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGT
+
<2*A6*@&$)A0/;''E/D>@H+/G,?,&.+4&F+5;#6#=*(D2>0"16AH#!A9F<F",H/=E>'#D8)?#&C8!:5'G(BHFE.,9!.(G7;F30+(%F'#(@*E#6<H>2($035%.7/"'24=CG"'9-?G-.B.==&&D+D6F=%'4H/.@?-16E9$G:%FG;1!->-=*3@<2/0C2$)A=$%>7#2?/;@!4C?-G?:$9.2F?&3?F!?;(.H>=3.!2B7GA&49;0$33.F*.!-"'!>C94/$(8;8>B(7776!*
@r5480
GCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGC
+
9#%,>+:/":G8B?"8()EH%1?@?).';*CD77F;763**,E#A*4"H),<4<A$026.1.A!"D2BHH$C/#?;9
@r5481
AAATATGCTGAATAGCACCATTTCTATGAGTTNCCCTGATGTTGTAATTGCATGTATAGAACATAAG
+
;C,'*:-1;.F+FH#1=0;<@B3B2:$&B?/7*CG.--#>5<(<&5F@:*%$@CE3G6.29*A59G2
@r5482
GTGTACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTTTCGGTGCTCNTGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCNGCGGGTAACGCGGA
+
)#)+)*"*)$%%#)+((*)+(%&($!$!'(#$)&%$'$%(+%%'!&+!&%&&)**(+"))+!&*!*'!!!!%'#')))(()$&%'&"%(&(&+!+"%$$$)+#+#$$$"$*!(#*"%
@r5483
CCGATTTTACATATTTTTTGCATGATAGAATTTGTACCACCTCCCACCGACCATCTATGACTG
+
66)9@7$**G7?64@&:+<&;--E0C49%ED68.A5($!DH@B0?0+(96+;'#-+B58$6)3
@r5484
TTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCC
+
17!*AG"A4?AA0=A"28A&32"+*9AF9&@C.99>!(?&>H020E4FC)>3)FC!E=<'),?(?2%!G709?2;C?:&BF0;D?=H%*41-H=CE3:<>6#5-E<ED@55
@r5485
TTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAA
+
*/-&$!$1.F$.?FCG<@/**H<#)#*8?(+<.3-'?G&D+(&#:;%2@A(#/9>#-<%*.8&4AHE'&%3)
@r5486
CATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGG
+
4<9+690$1!/*2:A02;'(9,0-*;3);@?4*AC&H,BFH-,A#$%A6D-B9B8B+.68=07-=5
@r5487
TCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGTAGCAACCGCAA
+
(FB=*&D28!2HHA<07*,3F):D/*5/02$->=6<CC24)+88,.".HE1(.7H?)(<@%(:1$4EH<3E;C*G5955$5$H-F
@r5488
GATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCA
+
@3BA;%5"A->*H'><GE*@#17-&$*A0&"6G"=H,5D?G4A@6&C8@<E,$?4@0##35'
@r5489
TGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGNGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAG
+
."<<+&#@$<D3086,$GE44%2:?%9591:),*18?7#++!.,D'%#62'&'&EF,(H'2$G9)C!.&5+"-<+&*#D(;H!@4'.F278;)H6DE#&(C*/HE:2->@089/@#>(A-G*3'*!2<1!))
@r5490
AAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAANCCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAG
+
&-9)926C<)0%#+H2H8<8C2"%%:-001"3?#(63$#GAH%#=$$?#>FF0<>>:)*D%H7?;4E%54.<,=;7$<11-'(C+,H=%@87%==.!7$?B65BC"<C7F#7.1)&*!/31,-&"49>C)3+G0+DBFF9D+G53:#ADC1<8,,;4A*!>7'-";(H7-*7$;#*/G86-G2B55F7E:#?D9BBG/+?;H>/1"23,C.<;
@r5491
ATTNATTTGGCGGCAACACAGGATCTCTCTTNTAAGTTACT
+
+8E;G50)+B#E@*!.G2)@7;?>5DA<C0G808:1GA2G$
@r5492
ANGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGC
+
!&A7'-B8/>7*09$+0;$*-<D+*?(0F,62+?19C"=+.F,B
@r5493
TTCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCNCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACC
+
*!*%+*+$)"(")$$#!"((&)'+$''""%#("%(*+#+#)%!#%%#(+++)%&&&)$#&!!*+!%"%)$+$*(*$!+%!("+&%$!*+)$!"$%&*!#*
@r5494
ATGTCCGCCACATCCGGGGAAGCGGGGATAACTACATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGNCCTGCCG
+
@142C+=A.C))?*'9,#?'2')>C(0&-G*'&$7&81,C#91.$:+:A9@8;2,,DC878H1:":#FAAE%.A<7F-;
@r5495
TATTATTTTNAACCCGTCANCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTNTGAACAAGGTCACCAATGCTGAGATGGCTGAAGAGATGGCAT
+
A18G2?9708BEF"/BF(2');/%C9&G%#F"DA+!HA0)7+&@;&*7:=%7C!D*:%G&6"547E"F?=-;$!&<&8=0*2<*+G>40>#,(/B&<60D0H7A4F&$#>DF*59;.@"2!=%'(/53"D6CF8#H/0@,EA1-#%#>*A.>4(135F
@r5496
CTCGCGGAAGTAANCGTACTGTCAGCGGCAGGACAACGTATTCGA
+
$C3%!>.*DE))2;H)*;4>$&#9/7,::1E;/G57/=A><5,*A
@r5497
GCGGTTTTACCNCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAANAAGGAGCA
+
C&>@B+8DA?=77+:B+=$545F&95&/=05!@&3H$'H$:6(1-+4=H-&"<=><<&"-#2G0=6
@r5498
TTACCGAAATCGGTACGGATACCGCGAAAGCAGCANATTTATAACCGCTTCAC
+
2925?$2437?'3/&F3G%C:2&)5BF,$%4!!=,$<?7+!#1@9"8+1CBD=
@r5499
NCTGCTTATGCTCTATAAAGTNGGCATAAACACCCAGCAGCATTTAGGAATAACCGACACGGGNAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCNGAAAGGGCAGTGTTTCCCAGCGCNCTTCCTGGTATGCGGATTCTTTCGGGAGATAGT
+
%(5.!:8"D:%>D9"?+?F7#?5&G6;.#&3*5:8(0&,H7(B-'%;#B;?,967#!#!>$6,:+,>A=5@D5!03;:%0&BB,+&#E$(<C4)GF4F.5)4:ED*1<+',>(H,%4H<.A0B3C(.<A+9/#<6'7870H)H8H''1+E.@1=!?2<;F<>@G0/E.:"..F0<952*"H%#
@r5500
GCGAACGCGGCATAACATGCATTGGACGCCANAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAANATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTATCCACATACTTCCTGCCTTCATTAAGG
+
/477H$4:B:C+<$<9:&!>5?5A:@%3@G&H$B+#6D(CG9,)@B@*#)(DE-"DF=G<6(#2@;+E)ABA485::3H6:'34?8G6EE?=5#+<!DA*1=!;7>A(>%3<*1#15=&FA?=9%C?(,F*,+E.("AD=.:84E;"'=9(>77/3>/B;9=1H@*-*.=/$'%*)D8F;?'3G(3?6":61#31-"G9*CC,=!%,EF?(,*"!1D0B-)"+6/:%;HHD61DH*2*(,'=:;F*AC*87G";'A66)?:=99C#&!3F0H!
@r5501
AAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGNTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTG
+
)(+CFC5/F"/5@&CF9<1@-/7#$*'(H(-.B/<0)&$*/;29(G)=?A=H?5=<34?5>::=5D)$&/%AB?*'(67*F53/#)96-((*92>$')H*:,%)$0!','A!F01&:B.A1'C$9"2D!88(G3$C<6
@r5502
GCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATNCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATG
+
$B2';,)(*&5B'G!=BA)%EH16?&#+;/+)??2/,7<1=4&',E#,D1'<H+:;;D,8!$*CC-;"F75A3;A-H);9#3&>D=8=6.8.#-5D<,-%:,?/<6'BG6'D$!+#:>>=A!0;#)DC72D;,B"953-=,7%EDG93,?9*96C!BCA16-F)D?G6C+.12*4///8'(CGCC9&H
@r5503
TATCACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGANCGTCTGCGCTTTACCTTCGGTNTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGNTCAGATACAACNTAACGGTGGCTGGGTGACGCAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATNACGCCGGACAGCAGCACAGACCAGCTGCAGAATAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAAC
+
&(&,@&'>%3H>%$#1.)(2E<9@F66->*8,A62,F>&52E$81!=$./,4&";;(D(11*D#/-HD;!1:.;2!$H@:2E=!0,:,:$G4+)'0*3E$E)F(3"@$0:'4<9*8*&!$8'>=2/+-;B.8>E6"("3$;6@??>111$1820+<$:F"/"447/<+D.G*2'(E,/7=;F?9D,+5:/:(&8""=!C#*;"?*:119%8/3&E(HB):+"%%5+G=0#G#0=&$;&04/>FD'%"$HABEBB5GDH6H'//D(,'12*H?8D6?%(8EB0'+$031#<55D!&+4&D(<=)H1=B%+A9"4>3;",7($CC("7<1+H1%G0*C7GC<:$%F"#0ADB"46D513
@r5504
AACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGC
+
'=&:;+*%%2-!G$$:?@2=192+'#+3/"%?C?!%432)8;$)4:;
@r5505
CCACTGCCANGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGNGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGNCGTTGTTGATATTGCTTATGAAGGCTCCGGC
+
A0G66&5;!073>E60#*BG*;6"19F.*7D#;?.B2#%3!+*))GF#A$H4;&-!C0C)!4):2'4.@<05--:)&F-(/3/<5/G35?;9&5'721F",9D1BD.!&3;<+
@r5506
GNGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGA
+
#/"*>?8&1%EB48):=465HEF@"),&,$??5;?'+G@9+5)@&&FE01A66<865>G'&3)
@r5507
GTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCNGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTANCGGATCGCNACACTCACAACAATGAGTGGCAGATACAGCCTGGTGGT
+
:/6?/9!;.97+G%!2C97)>C7$32<A0''>323?3@=/H3@4*1-(9#*;1/=)/$<0&C+1*'%;9!<#$A'/3,/,%16&9E8!=426,7B1,!1%A,5$1%95,6+!&F30<./.68-5''(&F!F-&%8!=:1:"8%+)@>DD&0H1)(AF:""%;7:DB;$):'*9;('&&*F29D?@DG;;?B%4AHBC$$8D190;A*%%3<H..
@r5508
NGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCG
+
%7$B'.-5%'>;F"58:*G#B.**B4HG8.7?>*E$H.%4(H4#,!(%>E,!D1A1$1&8$&%!A
@r5509
CCATTGCTGCCTGGTACTTGGTTGAAACCATTGCTCACCACCAGGTTGATATTAATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGATGGGAAGCTGGCTGAACGTGCCGGCATGGATTCTGTCGACCCACAGGAACTGAT
+
831D*$=?/%;B@<FF#C&EF,@>*@!G#F2H-!&(:)25#,871G%://A3%.98H1$<!>B+C))B%B'$+>50=?2"5<*3$*@D:18$6*'=37)(.*0AG8'$21HD0!@)*%0*)8%6C-,="<B,1#C;60(<3<-?$&$CD+26!
@r5510
CNCGANNNNAAGNGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACA
+
#!!(&)'!##&'"+)"'$&)'&"'&"&#)**+&$$'$(!!(!$"()!"")+*!)
@r5511
TNTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAG
+
.;E@+?-.'"*/>(238+2///F%D'0=;"0,"FF%("D>>6/9F1#>E0?#@H.!!2"E=
@r5512
TTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTA
+
D33$FF9-F);)"A;D'CC)=%H84+8"3('%AHB08'16),
@r5513
TAACGAAAAACGCCTCGAGTGAAGCGNTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATA
+
::/D,%,@-=1F=?,#?&:F).,1BH>4=5#(0974?6%D>)7DG?=&3>2!G!6@(06710*>/:>
@r5514
ATNATTAGCAGGTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCGCCAAC
+
)$!&&$+&)%%)&)#)&"+)!!*+)&"(%&+&(&(*!!+(&(%(!$+)'#+('!%!%('%$(**"*'$$%#&
@r5515
CGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCNTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAG
+
/=9>CD;%5/9B9?F8)67C1'?:1>DD%D=FE?31>&+D/A!G!@.7H/ED2+:.G:''**!B;--.F)CHH<?AF297CF6,*3>0:CC77>DAE7;FHA>2EH#5+E$$E&6,CF7G598!1-CE87B+F9+'F.H!,/F@D/"E=C9#,;2F8A4/=/@#>"G=!?"=>,!".8>"HDF?H5&#AC100D09=,97!HE<E.=FH?HH'7C!%(;>:GH8;$--1A6!'7,)+?(4:6@=/-$:16+$"H7E6%2-
@r5516
CGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGTACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCT
+
FDE,<-A6%=#EC2*25&%0E=5#=E/93'2F@;1#")/3-19D$A4C("9A-2&()?2)C9>(G,C@<*@#-.3E6B!!%)(>C+C;;H<"-.F%'6A!D"CD15(71B*$*8$"78H?".G-B;G+12?"3EE:>'AB=46%8H"6?*D#),=?7G6$!"779@FA8A*5228A7B%="G(9F*6C$3/%#)&54D5B:?5
@r5517
TGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCNCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGNTTCACGCACTGACTGACAGACT
+
*>#GAGGG04#>")@AB9)A97&3$B',>3)<FG),D2)CD%!,9&H%A;%*1F)-1GB%4.70*H6').+(")"EB8)H%/(/(H(8A?:#:022/?-G%G!-5$6.""-!'CA(CD*!*431E5"->!F:EC2EA-?B*"$-
@r5518
GCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCC
+
:=94$F0/#.%*9:)7EF##C&9=,*)-=7:BH=2+'@D-B$$D9C0-EA=(8
@r5519
TGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCATGCAGAGCATCATT
+
C144.1:G<FFA8#:054$=?D$64EH>&CD4.(E%>5&:-/.685B%2"5*<=5+B)B/80D+&4EB5
@r5520
CAACCCAGATAACGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATT
+
%H2H,7<3)C4<H9735(91)2F''H=?8A9@.4HH1)@4-85>.=?7&#"<,*D@"4*'&,,H=FB#27H?3':3AD)82/12
@r5521
NTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACNACCGACAGA
+
":8D<=5+>@!GA2.=%679E9>2$.'@?;B+-@?=7C"30)<1!&81&)$B!F:*/6.!78$>HD1,%E@G7
@r5522
ATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCA
+
-@5.G5+9E4-:HGF5%G>.9G@3E?$=*72?%"(B5;8&+;!%>@$2#3/.B)D
@r5523
TCTNCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATG
+
;1<"@*!-F.HC:5#B;3:@39.#(*&807H767-C05714DC9+0378F'#*B*7,>'H
@r5524
ATAAATTCTGACTCTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATACCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGG
+
A'C5C<G(6<.<1&C?;>1*/)%E.:4C3A4$B!G+.G72=2-<"="*#D;/$68#!D-'@;E>.-$$AF$C-EH,:5"/6#?6:%@@'C;9&24E&(7*$6$89C869H20.;':8(+'!-$E#?09$.3<,."D*F0=47;'6$(,DAB;570/9==ED>&=GE&$F-38CADEG031@>DCB=)+9G-87"C7)'=*5C;##:0EE;(0=+6.3++E1)H%+.6&3
@r5525
CCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGNNAGTGGTGCTTCCGCTGACTTTTCGCGGAAGTAAGCGTGCTGTCAGCGGCATGACAACGTATTCGATGTGTTATCTGNAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCNCCGGCATTGTTGACATGCCAGCGGGTCGGG
+
0H"C+8F:A1=1=ED01FCH1,%,,;0)?8'8(,8.DB<662B)%/D)52"D%,:=#F;!'BF*,!%B(2,"+&'*:CC%39/-2<D<G';#$-G/@&)!'>2+.((F=B4$F0*(=?F..A"?%C?&B>@.C"7H40?(/C80&1.*EE#7!G@4(1%E2=A0G4D-GE>:2&F50/)D<D27"!H/+3;7@%*.C7447@A('%=&54,0'!#8
@r5526
NTAGTCGCGGCGTTTGANGTATTGCTGGTTTCTTTCCCGTTCATCCA
+
!'$)+*$&+#+$"%"&"*%'%)&+**$*&(#*)'((*)%%'"#(*)$
@r5527
TTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACT
+
--1!/C,-#F5"").C>9G?47DG$!@';?#/'>C&57,(=@B&9/:/CG++=A0>6$=,!C6;0-7H4:&*279'/8@:E6.".&C,D83/8%>.#B@040-#E&FB76'DA6H":99$@(:849"$;..H*-
@r5528
AAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGG
+
@)AC:-<#)0:HGB$(99)*+8F"C+C<;H-GG39=108H#7A+6/7*+6D,9)%H3*0A<HD%--6:!-C0#;:%-+%H8;G*CH9-A0?F6+73%H1
@r5529
GTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGNAAGAGC
+
9>C&>C/9&,21(C14+F!D?1&2+6(0$"1$::GC."@A(@C6<-$,***(!47@H#)B)&HF'6G6+%)</",H+'G.(E/@*(41B:",7<73H*?D2A
@r5530
NGTTGCNTCNTTCTTCNNCANTCNNAATTGNNGGATATGCTCTCTTTTCTGACGTTAGTCTCCGACGTCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTATTGCTCAAGAGCGATGTTAATTTGTTCAATC
+
!%("&%"'((#$)**%#$'$(##%!&&%)$!!'$+'))+""$'#!#*$%++!($)!')!)*%'+!"'*$+"')#'&'$#((!*$*()&+'&(+*$&''#"%%%&""($#"%"&"#$'#'#&)$#'#*!&+"!$"%'"%++
@r5531
CATCAACGACTGCTACGACCACTGGATGATGTGGGCGCAGATAGCACATGCAGACGTATCCAATATTCGAATTGAAGAACTGAAAG
+
)#*?!((728A,#2"3-"A7"4-7C&7>@E7'7C3E>G?!;00=F34&&?><+2H+&+F4:":D6,@D#0!#>:AE9@-6:H:>7!
@r5532
TCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCNGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATG
+
9:%BE06><)G><1HH+=:%E7A,@3H1/D?.3,=*/*!=9H<2GC0G3&H((*E=539(2#&9-H3/*D%"H;
@r5533
CATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCG
+
@$&H6;/58&@9.A9!!6-=D#-2B&>>G?4G(A>-:"6A=;GG9)5'<."$38*DBG?:EG@!!CA/C'+A=520&;C,G36B4*%.G8.-28E
@r5534
GGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGNCATCACCATTAAGGGCAAAACCACCTCNCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACAAAGACCNGCTGCAG
+
59040"&&7DF!!E6,+A3AE0%*1!*>"2$%&E''#:-#2C8??G**+BE)'G4%*2:@A<>7*90!!C1EA5>%(0=<.D$E>&A<G=>>.76+,&+-,!/;:1.4?<#.$:9@;(/A?979HH8+>FC?-)@@>;=0+75CG*-?9!:0G433=-!0C&D7>9#(8
@r5535
CAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCNGATAGAGT
+
;03/F#>8B'<C(;469594DE=/)'1H32">1'<!7"*2-?*G$D(0/AA4(=.?"B9"C?40@3)@);$2#,E==*D1&=@C'4)4;.-)7@2-G?.+)2C28D'#'G'-F&1:.)F.:%+"=
@r5536
CAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGCTNCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGNCAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGC
+
C7;D1GB2,F6*"E!$$;F8&A4CF.<4'3A<>4?-;&5F/*5H/%F>%25"4?8F@?GCEB*($B?&@&-)B+1*=&#9,?+$'#"@=-'D"6-0G,F,3*4810D<C>8#9)+@DC(@"&,(CG)A:,G*A+,0D=&9=7BCBE)>D9))<@:3(1.73@H%4EH-93>3E3GB(?'7A41%9==#$0?AEDF0B<20$6
@r5537
AGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGA
+
$++%")'!"#'%))%)&'!("+#%"*$&"(!!&'+#(("'(*)*(*")&#"#(#&*!+(+#*!**)%($*%!)$%")'(&#"
@r5538
TGGANATGNGTCAGCGTGATGTTGCNGCGCTCGATGCAAAATACACGA
+
&*!(")+#%$$'&#(#)*#"()'')***&*)!!*"+"!&#''#)!+!"
@r5539
GGACGTTGCCGCGCTAACAGGCGNAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGG
+
9;H&<&B9,;#2GE3H*GB,1.-'4-?753G7?@+995/C=$=86H6.F40/B6GEEGA0.5
@r5540
NTGTGCTGCTNTNTGGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCC
+
&#$((()&&**##&"#)"'++!&!$#)*$#*&!'$'($(!!(!%#%%&*!&"("*$('+*#*&*%)*##!'"#!$+(&#%'!'&(%'$%#%!+!&%%(&+$&%#'#+'%#+$"!#"
@r5541
TGGCTTTGATGATATCCCGTTTCAGNAAATCAACATGTCGGTTTTNCAGTTCCGGAAAACGCCNCTGCACCGACAGGG
+
5E/5(-*&134$>:8$:&:"06G!-$F7=8365*-24.H?(@"+!!E<8:*E4D=C4*'>19&7;=,<*0-3,A?C&)
@r5542
AAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCCTTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTNCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCAT
+
+#&*!)!!&"&#(!&%+%'%'"%*'+"'#&#++($#&*)*&(!(+*'(!%"**$%("'*'+#&+&&+++%&*+!%*#&*)$&+((#$*()$%!(%+!#+$#)!%*!"**!#"(+$&$*#+'))+*++)%&#&("%$$*$(#"#*%&#+(+%"*&"*+&***((!!""))(!##$#(!!+('%*!*+%+$'$"&("'%)&!)!&%+'##+&('*"$!+%#$#!"
@r5543
AATCNTCNNTTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCT
+
))"&!$%!!+()!$#!&!+#+%&##++(%')$#%%&''!#(*!)*%"%+)")#"$("+*(*$&+("*"*%$#&#'(())*#$!+'("'+#((*+"*#*!+&**'$))"&##!%$&#)()#"+*'&)&*++)*#*%&$(%!##')*(*#
@r5544
TACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTNTTGTCGGTTACGCCCTCC
+
55".90;<;+((H%<H)7HG#!'6,.6G''EH=;E+3/0FG=B$C0"*E4331)EF4#+8.DA#8/8&1@F'A@
@r5545
AAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTNAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCNTGTTGACTATTT
+
+BA*DA79+5E#+@DB#<D/-,8G+?>342@*#H=;:197<62/3>F.,8-)78-1B69-#F/9DB=$A6+5F*#G(+F)4#,6==9*'><<E-4$
@r5546
GCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTNAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGCAAGGATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGNTCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCNGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGG
+
'?&%55=6.<=8E#H8:':#C)2/7)5>,(H47C3.B?1-+;*37:5<,E38&"2+$0#6#'A@BBA<A@?C8#6CA.32BF&&5!E-:53>1DAF585&%5$>&(.!>5.8%@C'/''"=,2?+&!(370<H;8#"5:F;GA1:).HF5?;!&'B/H==B+A9!23?DE73/+$,*/?EE/FC0@))<6!(!!*.*"G(*;D2!A#6&=8?5?F5&@>B9(E.47!(?8=A"E@/0<);,@CG1,"5="A=@*FC'<8<8='6=H'*B!*($@#&G2A1E'&?>,)(()B6DB$A<+5A0052&C4C,GD16??)):%9/5$.:@..E=H$@;,&=*4(EEGE+:):
@r5547
GTTTAGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCNTTGCAAGTCTGAGCCAACATGGTGATGATTCT
+
*(%&'(+(*!#&$*&!&*)*&!)$!&+$$++)+$'&*!%!+$&!%!)#%*$+*!'!)!"*&'&(!*$&#))#***&)&"#"(%$(*!*%'$$'*"(*+!!))#$##!))(#)&'!++'*'&$*!%#+"'+!)&"&+*%!+&!&'((!&!($"+!%#
@r5548
GCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACCGGCAGGGGCNGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTT
+
@7C'/3+A"D;H<C&2?';&0?&CGBE+9>2(<D8)H*#&#G1>*(8:"!&6#3:.>+:=/5-?"!C,,@,82H-;1(+?+(6>7"'4H6F*;::#:)@!(
@r5549
GCACAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCNCGTCC
+
%*!+&*&##**')"+"#'+$#&"&$"+&#!#'($$#$"!(&$'!+&"!!&&$)%)%"$")
@r5550
GGAGGAATCCGGTATGGCTGAACCGGTAGGNGATCTNGTCGTTGATTTGAGTCTNGATGCGGCCAGA
+
<:C$:39%)E844!HA":/)<0B8=>172'7A="7"#*G@&=2DA'%@)<C*"80!1;/B(,G&@DB
@r5551
AAGTGAACGAATACTTTTTATATGAGGAGGGCTNTTTTTACAAAATCCGGTAGTANCTTGCTAACCAATTCCTA
+
,+30%F<>+)%"FH4'#$90H9@+20$#!%E&-0DC+>B-(,&741G-,-,AH$'H?>#4?EF4F>&":.",#6
@r5552
CTCCCGCATATTGCNAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTT
+
>7E$EF)G:#5B2**82F/>4E9"2>3&CF:G86$:%0<2==#G,>,+#E<.('1/)4-C.:,7%CD
@r5553
NATNTGATNGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGG
+
%)$"*""*!+("""%!&&!%")%%""#&)('+$'"'+"++%&(#*$$&*#((+&$&*#)')$!)#"")(%%"+&'
@r5554
ATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGC
+
)7)@D0H,A:<41'5-6C9+?1!(+1@'%"/</(H:=E"H,=$!(%9&:;.+C$0<(G,08-.?<4*5'B'(H)+30<#/(C
@r5555
ATTTACTATATGGTTTCTGATAAGAATCCTNGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAAC
+
(+()1-"8&!F"-AD3D&80,*5/8$/"-H885'8A.>&/@,&::9.'$)1BC/(%9;3@*6B'//+43==B)%)20?>C"5(%A3ADC<D+G4D4@$(<!*!%'8A/2:0-/?F@
@r5556
GNNNACNGCAAGCAACNAGTTTCCGTCTTCACGGACTTCNTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGNGGCG
+
(##&*&!#%)''&(&$$#)$+)"""((!)*')&*%##*$!!%#*+++$+)!(+$$(+")#+$+$("%$+*(+#&((***'(&+"&&#!(##!*')(*%%*!(!'"&&'#+$+(*%%+'$#)'#*)'$#(#*"%&%!('''*%!+)%'((%!!'!)&)+%$("$$&)")'!()#$))(!#%"#()+!))!($%
@r5557
AAACAGAGAAAGGAAACGACAGAGGCCAATAAGCCTCGCTTTCTGNACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAA
+
69=>-$;H/#$E9!11C$"-$+1=?2*AF*8%1)+A10H=:?%/D+/0(:;.$93E(5#19<E%5;E.976(CG?"28+D$"9F%9F(5$DF<3G-BB5EG6G#F*))+1?71@/<>?D62!F7'>)=258BA*F-9+$#4E-*26&&EH>C>=:D-8'/+H!?8;1C);H>CD#/.,74/8E'"G&>'H
@r5558
CGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATNANCTGCTGGCCGGA
+
>E&!=)#,?6)7/4,09@3*#0<'GDB$<F)=*4**DA!"=;1$4/'G;;+5/+0+)3,H'1D(%0/:+<*H+3#.5=F!B-2"G55H=-D/(1-&,!B.FE<#C<'4$G(2EGD-##F*E
@r5559
CNGCTGCACCATCCTNTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCNGCGCCGCCAGCGCATAAACGA
+
#)5+.>,@A6#"B"A6E=:)93E3'5AE&7.F.!09.E.")G/C:3,5,&DD)?E'/499'H?.+8)3*/((9D><1$9>>95,35C$&**?E7>3+@B
@r5560
CTGAACGTCGNCNCCTNGNNCAAACNCNANCNNGNATGNANTTAT
+
###$$$!$###"!"#$""$"$$!#"$!!!!"!#"#"#!"##$$$$
@r5561
CAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGNGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTG
+
@B$'@@3H!0#.$6%02BA-86!G#$8(%A55B#1,7;D"G%84C=<.EBB7/:?CB4!5H+E'8%GA*9>=E"*'&>H&-?.@"3<!=,E7FBC@B.7,*B=%#*/F"4#"?DAC6B:#C8!3?4"B6B<=*G05)".3=)..3;,&0B<''0'E?#/;7+CH;5;D%$@(C!"A.5%#+C#A#,9;@=
@r5562
TGCGAAAATGTATTCAGAAAATGNTTATCAAGCCCTGTANCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCNGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGAGTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTAC
+
+!'!*!&%)+!')$)#!&+*%#+!!$)#%('&&%#)&""%%$&%'&++)(&&&"*+$**&$*&"")(#'&!(#!"$*!%!%'(&!#*+&))*'&+(#+"(+(+""$+!$%)%(%!$!#'&"%#%((&'!'#!!$!"$+'&!)'(#&)*#!($'$&)"&'#**(#))&)%#!(#*%'"!*+*#""!+!&&%&((&"&$*+!%#'+'!)
@r5563
TTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCNGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCG
+
AE;;/9BF+:&'+11@0-8:G)*87:=6712F<B(:)<FD+<0#1?5*@91-2.>C13"@E&<$>52B,-.H&5CHBBH(G<8B=H,4+<@D/4.7/@:9<%0A19+83+0#+B4-5:!6:7D$1."&32!:)5C4(:AGH?8/+"F*AB5'!'A.!;'4E@E!$>)&'4.@>'?#&;*>749-*:!?.,=*1H:E*-/
@r5564
CCNTAGTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAANGATTANCTCTTCAGGC
+
()+!"!(%'$('))+#()(('+'(&"*(+(%!!"*('"*(##)('$)"()##%+)+"%"(#&'%'#!*&)!+(#+#!+)**!$'#'!**+'#(%"!("&#*(#'#)%"))#&*&(!''$('$(*!&#
@r5565
CCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGG
+
8?-$869..*@(,"AB>B*$,&&<:@,E:)2/D$;(*=D(1=01$=&/+A>318:4(3G>9&+.9+5E1<#$EB8%(D15/B*?
@r5566
AAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTC
+
C>?2&5>,##D;<17:H'0EF16G!21#=021E5>H(.*,.9A/9E+$3)5-=6252#"-79@43-(5G./
@r5567
TTCTGCGCCTCTTCGGTATATTNCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTC
+
FA'F.%<9.(A?-.A)B-#1!?B-<G,B03'!C2'H=8(;?H6$7.'3B?5,C)48'9F@77#:-58C
@r5568
CCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTC
+
2??<EH/06HFG6/6$@$"15"G&G$'2'!--0&C*@F/6&9H;8"97<)<2*&CA&'G.%)29%EC)D.B56)3(&@(D.<G<F#AF-(5<*"04)>A8E+D0FE43:$*B/&8="847ABHG@C%#:&#G;)-0*B),?,,H!#,:@#:G;((!)HD)D)F5H5BC+;,%E;(4,$$27,4,@+A#<<8=$(7;33'.0!FDGFF"D<=-)=0.:<$)B##E%=,30#H9##39,":#A=
@r5569
NANAANANGCGGNNANNNTAANNNNNNNNNTNNTNTANTTGCNGACCGGGNTACATG
+
"#!"$$$"$#!#!#$!!$$!$"$"!!!!"!"##""#!!"#$$$#!""$#$$#!!#"$
@r5570
AAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGA
+
@9881E?9.6*?E&G',!=$.C#%>/?4H)C3#%*4@%G6?5&>6G('E",-
@r5571
GGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGG
+
9HA'E.%C+H-1DE&90B#+A=>@>+B*;*6!%7=3=%EE254BD8
@r5572
GTGCTGCAGCGCATAGCNCNGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCNTGGTCAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTAACCACCA
+
"D"'!5.6+2$0>#;%57?7->8(/.&-#C:CH%C.!.;C%0D0?3H258CC,;>'>EF@=?*($".')$@2!F)A17);:%;,86>;*"B"D;/8(G;3%=B<3&B+$E73&@/2/#*H(3:'!</4+"+:6;F#":FD-$;2@=5C2<3>&#5">*E?63,C$B%+!72>)"#<F6FF0*5C55,C2F>:?6;#,@>%<.,8;>>E4<(A
@r5573
TAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTNTGCGG
+
1,A&G##(FG4&)83=6-,+8C"20(?4@<E8/1"@?4F%92FGAA@7))+7=F'>E>#=2CA&;D+.H68,=(-%>*E(:@
@r5574
TTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGA
+
B82,='E1/4';2+;#+C;/BDC+!/'!#FB24DC!AG)74-EC?'G/41E@*?EC6%
@r5575
CTGACCCGCGACGACCATTTTGCGCAGGTCANCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCNCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGNTGTACG
+
BF->8$G1-F"3/D<5?%F:7<3+.=,)9>/F->G%FB4A(70.$H#HC0)E=B)5D&&7%)B)7E'(H(#&##.9/D-@,@.*>2"0?A9DC6#E>EF3)&*>>&>5?!,>=(/=$@0601@E#&5$@+/>*+F6A,.5?!(!0%E('B":&3
@r5576
NCCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGCACAACGCATAACCCTGAAANATTATGCCATGCGCTTTGGGCAAA
+
)#C<G0/?F"D?-75&4$:E..06,G#G!72(CG5!?BD$-1H@"<<$!->&9C0C2*1,9@BD85+1)%1-175;;?!;/BC@//&$=/<9:(')AB:9G&<E?<'5
@r5577
AAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGT
+
1FE74#!69;&.4(,6C-*=033FB%@;F=$$?H>=:+?+*>*#)1*?><H321-B<>EG%743C#AG$EFA.+"1&'!H51'B:G2E!E,67!1)$F8E$%-#7B/<,'"E*/A)#<!FC%:-:..@%H?99F19'G9,*3/F)2B?9*.1"!1'?,:C9;5%;6&!?%B1&E0.*!7",E<3H,"D7=";1/46;@8%.E$C)>E!&?:
@r5578
CTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAA
+
,!"/B)=&#:C;5?!H,?2=,0#=%<HD51,E.>3!F4'D1?5=;0B'AH.;70%=.0?!.0<)>$AE"=B&%+(&$#83=5EB;,0*A7;FFB>0<'.?/E47#+2HF0(*6'
@r5579
GGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGC
+
/&1;E2'$HH*1A3F#?&:'4H65%CC8!8F4,?4$C*786/93=+<7B;>(68BFB9.7;8FF+B#&B?B-"0<G;7+8G'H9H,;+B2?=F%F'6<<B2(@9"
@r5580
GGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGNCGTCGGGCGAAGAGNGGTGATCAGTTCCTGTGGGTCGACAGAATCCATG
+
91;G3!>6>E!#HB98%G$+:;>A'"BA?F:D--)DC"*EH9''H0%.@*H/F!7G3)2(7;.'11&=B!1>E8;%'<GH2G>0E(DB4EC2@>/H#*:2"D'/#7@G7&0;(68,@>4;+B4?<&=C)<1"E)8F),<>E>76H&&H,%.
@r5581
GCATTGAGAACTTTGGAATNCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTG
+
/2..-,9:>7B=,*A(!>(+<C=4,1),<%=9(F%;H*8+:(5;>G:1F$<,4F#(2?16,-$=1B;$FG+$>4$2*(?"@-&):<4F47?8(@6(#:"4A9?,
@r5582
TCTTCTGCACGTTTTGCCGAATATTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCNCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGC
+
:HF"98-+#?384$<;=E=4)A,BHH%*43FA05"E')F7<+>.'?G!2D%$*->#>*=$<@1>*"6108H69&/<#963D&2##.>30/3-%6-4-D4*#EE9#<(,D$B.?:?D;()9)*0F'$9*#8$/;:
@r5583
AGCCGCCACGGGAACGGATAACCNCACCGGAAACAATCGGCGAA
+
.HG<"*+674?(&15FE<@,2-0?-30C!C"B,H.1=7>@;);H
@r5584
TCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGANTCTGCGGCTGCGGCACTTTTTTCCGNTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTAAGCTGACGATGCAGCCTGTCNGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGT
+
-,*A$71%3>1G4*$&/:6$BF<A9G<**'.68$=H5/>.=#,&;+503,:@H,2;#DE997+5!,525;+FF)*,8#A%9#4(=6=0,7,#E#52?74GA>"708:"$B@CB21"%"/)<,BB,G/7HD&'"A61G12/C$'5*A;(9.CB2B45-@6A"<#!'(BC'F1$)*38-9*&2-022#A7C>'8@?#5
@r5585
CGNTNTCTCNGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCNTATTGCAGGTNGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGNATGGGAACCAAAGGATATNCAGACGCGANTGCCTGTTCTGAAGCCATTT
+
%*"'"(!%$'$+'*)(+$#"&$**'+&"!$*#("%'$(*$!'$+&'+)#)"''**'&)''"**"!!*""''*&+'$)!&'+'&&((#*##)#($$&('!'+"%$&!)+*!&#()+#*%"'%("#&%(#'++'(($")*)##()%''+
@r5586
TTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAANCCTTCTGCTTTGAATGCTGCCCTTCTTCACGGCTTAATT
+
-<4CE14-4-<3B=/HG<:D#0/*9/E0=D*3#"%2.0'GA451;0=695G,<!E*+80*;$C#;AA2983#=E=**.
@r5587
ATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCC
+
4A!4,72,0(D7?@&;<+8!7D$)>$!9+A>$B,42*?"03=C>G6
@r5588
CTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACT
+
2.C(<A>:C.,59B,+;<"@$#>-258G(@:1,/:890B')E"B"D@".>*"C"7."@8#6?5(1(&'7*C?520(@C:&#4$>:55F-G2&-%9<&-7DG#"@'?7!8-/A=0?/=4>0)='D:73(+=F3>;>??H;A!G:125+89*H
@r5589
CGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGA
+
4@F$+?=:DH!1'#?HF2-D;47@;.<2C090>+'/90!C#621C-1-*!E++/F$4B#D6&=<4
@r5590
ATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTNAATTC
+
13-1/+!1E!B9A#D?'.;CGG2%#E:H<&/3.>4<,%9==*
@r5591
AANCGGAAGCAGAAAGATAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTAC
+
&)&$$++$)(+&)""%&%+)+'$('#(#&#)('&)+!''"!&*&)%&"!))*!+'"($$%#)'#
@r5592
ANGCNGCNTNNGTGCTCAAGCTGCTCTGGTGTTCATGGTTTCTTTTTTGTGC
+
&"(!#"(#$%'+*&%("$$"##+!$!'"&()'"(#&'"&)%&#&*'(%&*!!
@r5593
ATCATCGAACTGGTGNGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTAT
+
+''+&"(*#)'"&#&#%)%+($&!(*+'$)(%+&%$**+#(!)"'*$'(&!$')
@r5594
CGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAG
+
58G<0D=%G*9H<!>1>&?%81.E52!H*D@H5'*B"-:G2B3B$)H6./7.
@r5595
CNCNGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACGGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGNAACTGGCGCTGGGGAACTACAGG
+
$#%$+$""&**#&$"+'++'")*(!'&%+)%#!*("&)"')%*(&($$+'&"$*!&%)($(!'+%"!(&%*!)$*+#&#!##)&%#+""""%("&"+&()#$%+$'"+"*)&'!$%%+#%*#+%+'$'"+%"$*!+*$*(%(')"(+#*%)+*%'())**"$+(#*''#*!'$(
@r5596
TCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTTAGGAATCCAAGAGCTTTTNCTGCTTNGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATANGTCGTCATCCCA
+
&C,5+97E2#D;2D*"36@A42,>"&<<D57>B&C*B163E44F<,<78<F88D?##AF-<$)G2G$:3*;C8+0D7'F=-)H62A=7H<(69%ECGDHA#EG-4,AA(,+210&3+8,0>2>">9A63#%.,8#*F(()>+H%+?(*.H)%#FH1?@1$17=;.H"9HD(
@r5597
NNGCTTNGTGTACCTCATCTCATGCGAAAACTTGACCTTT
+
'&+)#!')&&*###$!+)+)$)#"#!)!(%*!!)$)"!!*
@r5598
AAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCNAATATTAGGAATGTTTTCACTTAATAGTA
+
HCF+4)G,&E%'G9A.=,-+8=%9H97.+647?/F?*/(6;6-4BB14&F'AF.F/(/<98AA4)>:.3GB0C,9:##=-='8!2/+H166>@/&$#.'EG3)#$+'B)&*070<BF:!75FF/9(9"7+G<<.A/6!+:*77=C;1%(1'!
@r5599
ACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCT
+
2#*$(.F,"8>9C0>9<'63*G)>1=5H=G.5>&:3CF8'.!)$=F%!.A%?E!)47->%'<-">)1C<43!!(-D?-!A19.)
@r5600
GGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTNATGGGGCGGCGNAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAATAGGCCATCGTTCGCCGCGTNGTGACGTTAC
+
)+)HG(?BHCD+6,F'/BD<F=#*-'7@?H,331H>EHAG(!A+!9D7-!B*1.5"==9!$4!4!F=$B@.84B412?*4#1.D+3;=7($5@2/@E>G.73'8.(E?1B!A;,!';-8?&:+!>&:1%H0
@r5601
GAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCC
+
@'()B8>$-)*5?H6G;46@49@/$:271B@7($'-5!*F<
@r5602
CGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCA
+
&=D?!4)9*(/B@!"$D4G%BH-'&!>FGF52D8)>$&08&?E*0#5-3;&!H
@r5603
GNNTGNCGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGGCCGCTGCCAGAAAAATGCATTCCGTGGTT
+
&$&''#*+)()'$$+&*$#$*#%+%!)$$+)*)'"+)&!+"&'")#""+"*"(*&$"!#()*!'+&&#%(!")"*))*()#&*())!!'%$$)''($&%)(&'("!")(*(!(+!"!!&%&'
@r5604
GTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTNCGAGCAGATGGTTGGAATGACTANTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAAGGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAA
+
6F%!+EC7<5:-F5<39A/)!.)C/?0"9H'(&7!+G>;0.G1*B:$H:240B/C9B*&0D##BE<5%"'"(+?A%+@C8CH!&;.#;&GDH!-9451-B;*C577.AA4-7C.:07A-.D/83H>%:F3$#?$$5!H57%?&&#?2C:;#193@);6*9%5-B7>*:(A4'%6'&6&>
@r5605
NGTTGATGATTTNTGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGNTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTACTCAAA
+
!5"'A/H-E'2E!'(>C6(/8<'B:+27?)D;4;"H:+2)2.,(7+):=F!'5;*C&1?)B)@<9BF*@$:<.4<88-/$5"#)?@''H$EG#E3?!E@(E78HG/3D5G7#;2G9C>):0.$5FB?$E&C
@r5606
CTGGNGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTNCTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTCTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCNGGAGGATTGC
+
::7*A..>+=5!A&A&$4B=?1B&F@9+1%.6D$"$+!H.<$8";?.C1==#"(*+<;:2:9-6G?(2)".-%4:!12'0;?)*DC<F3.)$!<3<)A!,F)'"C!F6%*&881E>"6A'5,7"62/2HF%1@%5&='.EA(D<;#35=7+@0;H<06:"*835-'0F:3'H?D5%@@2@02&:A3$@4!B$B2"F6)B1
@r5607
ANNNNGATNNANCCGTTAAATGNNNNNNGNANCAGGTTACNANTAC
+
!##!#$#$"#!###"$"#$$!$$!#"$$#""!"$$#$$$$!!$$!"
@r5608
GAATTTATCATCGTCCACTTGAATCTGTGGTTCATNACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGANTNCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCNTTTTCTATCTANTCTCATACAACCAATAA
+
-?43/&*4>=<"!FGFB;$#"A:@,F6%8@+4!)%*1)"(=D*>(!!0F0FH-;<D"69E.'<C$,A*1<5E,8DH'7(*H)D@743!3E:;A5@D66(H=(9@@":)/H,FB53E>5/1#=>H09!56&.-F&/G@F"8#7&A%F=3H(:8,,C":,!A,%:")
@r5609
TGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGNCGCATGTATTCCGCCTCATACCGGT
+
'B<C3>,D1E-=813!!*"?-6%<#ED,$*H/-3,5754>9,5<,*=;%,#H;#::G6C==>4A@*(#&0B)3GH2E'96A82C9<+E>(6*FA@AHA#-DD+HC%7"C$;,F)E?/:<780;?
@r5610
CAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTT
+
.3D(38F<95-<4"EEB#1FB4A.E,)/-;$!$0,88"C-7+'8>7?+?05:!E0'=8??=/1,>
@r5611
AGATTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGC
+
'7BG##??+,*4=C6A5/)9C$F!.H$<#C0(-*&B7!-)F;C6(H,B)29*-02CB?,&F$@F<FG8'08-+)@!1.DE8#%7A:.">6.8173C1H63*
@r5612
TGGGNGCTGCTCCGTGTTTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATTGCGGCCCGTTTNGCCCGTTGCTGCTGTGCNAATTTATCCGCCTGCTGCGCCAGCGCGT
+
'!$"#*#)(*'%'(()!!%&(+&%*%)"&#)($$()&*!+*$$#"$(&'"%*&!#&'%($+#%%!+#%!+&+!("*%*$%#%))%&('!'#$(*))!!&&++*('+(#+)!(!*+'+$$*#"#*!
@r5613
GGTAGTGACGCGCCCAGCTCTGAGCTTCAAGACGATCCTGAATGTAA
+
7"C)(*#7C?+8.+#'1)/7%/$<B:+F93,</?=$:4+H0<D#+.!
@r5614
TGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTNTGTAGATGAAGGTATAGATATAGAGTC
+
9B0$3+&55,93>5>,<#$#;&:G#68F>(++%$/F/3@@8G,696F%:23?G&-@20B<2-@
@r5615
TGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGA
+
AG:6'09#A)E5+7"G2-G/3$0B,3")D*A*H-!,H&?:H.A=1BBC1$>:#'!83'
@r5616
ATCAGCAGAGTGTTAATCTCCTGCATGATTTCATCGTTAAACGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCAT
+
0;?.#H-C)1>-!509>?=B335FCA>G/<70B#/2#0/'!92-A>8F;/9>C<-":"8D75))HB4(=:F:3"=8?;=-8.>3A-9@*#8,F.6H$067)@75B.&?4%'G
@r5617
CATNNTTTAGGGNTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGG
+
)()#)&'+#(!#+*!)"$*"$)"""&"))"&$$$$%(!"+(%)!(*("*!!$#%)'+%%"#&)
@r5618
GCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACNTTTCGCCAACGACATCTACTAA
+
7-=%684*6H'F=,0+'A!,HA#@@0<A#BE;C"(#.32=;!+(C)?'CA.8:?"$BG$+!D-H3%3->=-4)<'-/$1"(5B.>272!B2.('/?4:&B?1F8:6"+@0-67
@r5619
CGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCNCCTCACCACGGTTAATTCTCGCANTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTTGCCCGCANGTGCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTCTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCA
+
6B/3A5>+/56*E)G?$;(10)&?/CH3?>##C1+DB48<"50(.>H=!$(+1D04%C1E<2053+F143@(>A)D/,'"EE":HC%92-#;=1))F/.;@H657&$!HD!G%C9%B#1'38,#H),?7%/C/,#4/):A?9F?21B8")>1&C&=6&/;@/#&"-6"(D"C3:;1+@*01G75HC)D6"4@17!-+&$F>;$"-A,#2@6>9G+5%/+0(H0-CH"0D<#!A00;#6./333,.!7G-&8D
@r5620
AGNGAATACACGGAGCAATNTCGCTCGTAACTAAACAGGAGCCGACTTGTT
+
9/>FG3=<>E!>D??42E$+B;:#CD!*&=,)5$#"&3*A**59%4-!!1H
@r5621
AATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTC
+
?/CH@$<2!;4'""62*7BC.:HC5?BF9G*9@7A?#"6C!<'"";8=<!(,<F
@r5622
ACGCCGGGCGAACTGACCGNTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCA
+
,?*@>&-D2.DC=8,H<<#1FC0,DH)%-:2-C6,(4EG6).1D2&A:?4,#-/40"?DA"<,B
@r5623
CATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAG
+
G?"$4G35>&F6!'#*,16G3HH78>.5*>D+8?!$+*'#85D$#0!EA@=3D5G7'D7AC"E-
@r5624
TNNGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCA
+
)#(H%G579%8?1#-!A&G9278(F3EFF$"<C,;-F"7:0H*D5)2#*&!<*)<E9?.$2G?B4>>5!23E5F3G5>E@9/5<<!GH7%EDCB)=;!26GB&6*$86G"F:(-%0%?"A-/"*'.?"E7A0A=+;A"7E(H6"8%-@E=F?,1F85#><>6.+$,!<B>E'8*<%2E@C?5
@r5625
CCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTNCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTG
+
B+8E?-/>3G307C0.;B%7)#*$4G,0=5(42'A"3+;,>C<*2?(6,<+$E*$D:'>G29(74A/7>G6;/236@:=H&*-%!.;G&975*G:2F=;7E@:#FD8#>0
@r5626
NGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCT
+
!+++*'"'"#+!#&&#(&'&+'%%)+!+(&%$**(#(&%(!++)&(!$&"+)$#$#!$%#)+(*()+#+%
@r5627
GGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAA
+
H*8C"<1>C,D#92'H''%;(1/(15.:9'>2(=$$&,01@
@r5628
NTTGTAATAGTGTCTTTTGNGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATG
+
#<?2580:D6%6@>*"#!%</@F96,.;@=A%<*;A9>1D-:(H/A*6D%?2+#*+H<B:B+&$
@r5629
GCAAATGTCATCGACGTTTTTATCCGGAANCTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGC
+
5D'*-0+CH.49<G#/?;?3(%E?BAC5H6G<?#90*(G",D),)<403.)83C>.1'7"2:67/9"$8)EF@:41C<(?<
@r5630
CGACGGGNTCCCCCTGTCGGTNCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTCAAACGGGATATCCTCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACTGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATG
+
6-H67@5A:A30%#5(@22!(*H'!,.A*G5:G;&).)-E1972CF-@4"=.$4<*76!0)#9@DE)9$>A>0)A*!*8G=9+$689>9&B&<+@5GE*/62(BD4%>&$<,416DA!#&41,:C'C"1<AH8!:4-'&7?(*94'<3F)0=E*B5@4>5$E*"C.,>615DF;'+0A6%-44':'#8@5*?5C:=10-0#&,9,/,=$-F'B+D7"A)41%:4'.*9/6"+EE7H';G*D#);.*>A==,)A<-#C35'*&*7-:)?1B",/#EF5D<'!80'"@-C%=9BE8./&DB@)?C82$&21A:6?&5&51H"G
@r5631
GGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTAC
+
-?*04(;&3H??;7-,E?&)&.,G$+9*.F(&",:"%!93A#D'+"!.,<2##9%
@r5632
GGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCNCGGTGGTGGTGAACACGGTGGNCTCAGAGAATCCGGATGAAGCCG
+
<'5;-!:!GC60G7$H33&>0C("G;%+F=#<%:0.),,AGG1",");2EE:G5E"9A&&,*3-8C.##04+1A'.&>.<#40G3D)F.#-.#E%E13%A
@r5633
NCTACCGATGTCATATACCCATACTCNCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATNACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCA
+
"+)&!&'")$"+&'%!&$*!*$+#$(%&*+%$$"#))##&#**'%%$'+#$"+&*&"&!'#!')%*)*')$%$)*$*$)"*"")'#$"#()*!#$%(('+(*'%+%!*)'&$)&!%)*''+''+**&$&*"$++!$%+$(#!!&"(#)&%(#'(#&&****#+%$'#()#+*+&(!**!$*+(*%!*'($('&)*#(%(*!!!!*%')*#()#))$#())(!"+))&*)$''*$+*#&#$+"###"#(!'%'#&(&#&''(+#!'*)&$+&*'+!%$&*!&*)'&!"'&**$%*#!(&%('%'&"**)#&*%))'+("()$%+("'#!(#%&$$"&&'
@r5634
CATGACCTTCGTGAAANCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAA
+
B>7=7.;H&8>?5!4(%;=>9E4D'/?3!7$D<,*2"B>?,5'5E*;C+7:E>+%,H(GE2'+AB7F'*-C9$*(5A.,!6(8
@r5635
TCTAAAGTCGGTTTTTTTTCTTCATTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGT
+
/9%0E,1A,;),A(&F'<267H+,+H463'#56>*8?;87G8=%D0-:2C94E!8<A#/8B))18#;%$%(+/D000=4?*-"+GD$>DA9::!:2G7F#*DD-@4&?726(#HG%
@r5636
TTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAANCACACCCGATGGATACGCGA
+
5?9G38F7D)'>8%+A>C?.0'G9*7+=/<*-*6+;D*4=3%8@&F8#.1(%,-5A
@r5637
ANTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAANACCTTGCCGATCAGCNA
+
-(6!/<9)-'H$=@>-!0*.GF7."(=(H47<B2'2=/;B*;,4&*'G4*3FG;:/4
@r5638
GGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACANAG
+
D=*8-C"&8'1BG9'21!CE:D?@0()%-EBF"1+8<D(F?<<<F*&,.5(@A#;#/=<;>)0!'/C
@r5639
GAGNAGCNNCGGAGTTTNTGGTAGGCGGAGAGTCAGTTCGTGGTNCTGGAGGAGGCGGCGCAACGTCGCCA
+
('&#&)()'%*)#"&*$!+)!*'!#*#%'!$)!+((''('$*''*#(+)"&#*'+#%#(&&#!(%""&&!+
@r5640
TTANTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTNACAGTACGGGTACCTGACGGCCAGNCC
+
FF:6@E0/3&1H?-'"F.><A-3+<5<:+(AC@>-)/AE7>*9%F#%@<5&G?A9!08@CHF$!:65@C@)=03BBE9F5(=D=<B=;C"D",$EH
@r5641
GNNNNNNCNANNTCGCNTTNCTCCCNGAANNGACAGNGANTNNTCCANANNNNANNNNTNANGNGNGNNNTAGTNNTNGNGNNGCNATNAANCATANNCTNCNANNNNATNNCNTCAANGANANGNANNANNNTANANTCACNNGNNNNCAGCCNNCGNTCCCTACCNCNGCNNNNNCGNNCAGCNCT
+
"!!"""$#"!"$!"#"$!#!"""$"#!!$$#"$"!"!$!$##!!!"#$"!!$"$"#!!$!##$""""$#$""$##!##!#$"!!!!!##"!!#$"$!!$!!$"$!""##!!!##"$""$#"!##$!""!"#"!$$""!!#""!!!$#$#!"#""!##$$!""$"##"!!"$""!!"!#"#!"$$##$"
@r5642
AAGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGCGTGATGGCAGAAATGGTCGATTCNGCCGACGGGCTACGCGCATTCCTGCGTTAACNTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAAC
+
$&<A4>F:@&'>?#4BC4!38FD6DE*!='G@>C(,5D5?6,H=#<)+D-4!42'*D.495(5+8C'A>3"*@%$:0@*88C;A*$09<AF:2@F5B8A&07@G;4E2"*$>4,4#8F*H%*D3E,0D".>+?+E<"E,5GA)5:D8(8&$=<F8',/
@r5643
CAGATTCACNATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATANTCAATTTAGTC
+
***#"&$&'"&+$%&)&&()#%%+'+$$(&((''%#+($#&!'%'$)#$$&*#)&$%&*#)+#$$%'))"+)(")%!"+#'"*#$&++#")&("
@r5644
TTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGA
+
$1"?7D3#E#'97-!@(?(G9,$)3D8%&@-?!1.#C-'5$DDG'(7680>'*F-@A=):<=&+-%8
@r5645
GGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGAANAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACNCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCANCCGCCCAGGCGGGCGGGACCGGCTGCACGG
+
5&6=!-)%"$H"B?3;%7GG!/G6;C28!93+B);1EFFF:)F;*F?H-+34B7>)6;6>G?HHE*%9?*.*"<C('=.3@?BC2G"0/&GG=,'G);$C7#+/=&*>81+G58!%:=B!>/14-C)<1&*,C"C%1$8-HF$D+E->7>,GC2?D$&$/,'%.@7>4<<+;E6)!GF'46#</19&!$'GB2!2<>/)D7).5E0-/"@0/*GEH=+,6&(
@r5646
GGTGCCAAAATCCTGGATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACCTTCGGTGAGAACTTAGGTGTTTTAACTCGTGAG
+
,.F9)D9E(79"$,$?>)E!8)&=3<=59.G-A>!#66=77%@-!>4(+AE(%*;4/@7'!8?$/(7#A)4%$.(*(',+.9$(853;A/=4B(!EH=BA1#<<5$.GA
@r5647
TCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGA
+
1CGD+A#DC?*>!9)FAE>6/D&C"(-%6$>>H,;$"G-9.
@r5648
CTGCGGNCGATCGTTGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAACTCG
+
*)+!*!%')"%"")($$+($*'&*!))+$$!++'"#!(''("!&*()('%)&'+*%('$)'$'*&++#+("%#!&#&''
@r5649
ACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAA
+
7""D<45%-;9/*,="=E'=+F34'4B$+-3<%1H<$*H:E3
@r5650
ATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTNTGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGANACCCGGTATGGATGTGGCTTCGGTCCCTTCTGNAAGAAAGGTGCGCTTTG
+
B2(3B(7GH&?>-CDH"E#2(9C$"2<F'(03322H8EA%)&=50GF7@:;%4G:B@B$B&G"07D1"#6B&?5/=.CH#0!783("0FH+,F1,B';!?G&$/G4-H0@39G%;&)4@-8;/,$GE2B!0"0=2-772&&1C79108BD0!BE-?""D#"(8,;,73&FDB;@+?"(A2.>&7=;56%EB/63?C'@E,'*5DH;%##$79#;=G<B-*+A<84E859/ED:%DHA!>D2'1C58)0$51@*9/>E++9/''EH,8"<=9H<"5D5-<F,D?F7G>**?F4!F%/?0:G4.<'(*+H&.%.4,@)C<3?>%52#E
@r5651
CCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATC
+
#@4:!42<#'?E)"H48?#:G$@62#C&)<1<).:3/1FD;#3+1!(H.0(@'#F/H&6*
@r5652
TCCAGCCAGCGACCATGCCATTCNACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTCTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCT
+
:?3:E-/H$GH021>E)99"7"%0'/,@<D1.59;#A$6%D2='5:D"E<?G63.31>-1$2B;3.,)1&%->@@3.1<?).1,?*4H9A=(&+#$;+'0/($EE?BG$G/*?HH1(&::%,41%*+/28)3F<+CB@,067@4,%47(*6)00$.D<0B;D)
@r5653
AAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGG
+
%9&D&'DF?%462#>D0(4&81,8A=-&&$98*9%@%,=C:%:&>')
@r5654
AATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTT
+
D;3:$3%.?<2&E*H:4!E$,GEH:/E*E;;1?3/#GC7!1)"<C909D)2,.?>D2$GCG!'A"D*A88>18222
@r5655
ATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGATAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGT
+
2?1%8DDH61:?9D5%*A'H'G?"A3;(?-0!):>&C9'9723=F"!(50<)'A<&:=",>&&&.)-24A5/B=,%2+!D#>>.%DF3+%6.*F!;&&6*"(#.G2+&/C+=(8#EF1853";6-0==9C*&
@r5656
CCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAG
+
.*6?G(1,109$@#<0&35'EC>*;4AA0/%-%:1!807,+(>>3",#+6
@r5657
GGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAG
+
%&*#+!&*$(')$$"&'+"%!#*)+(#"*)'&($##('*%'++!(+!**%!%$(%#")$'($)'"&&++&!+(!""%"##!%$("!!((%#
@r5658
AAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCG
+
>H@(/!'C2D9:/85<"/>*F";5#A2527H30=$80<?&8"3&>9?.?5&9
@r5659
CTTNTNCTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTNTTTATCATCAACGTATTTTCTGANCGTACCGCCACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGANCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACGTCTGCTATCTCGCANGTCTT
+
#*&)$%+*&+'"()++!&*((%+"(%%%#%#%#$$("#$($+%$!)*")')!"&"%"!!)'"'*!&!+"#!('($%%*$&&#+&+#!$+'!"%'!&"&'(&(!"#)+$*!(()%&!$$%)'%+!($!&%!"&$"%&(!&(%"%$#+*'+$(')(*)%#$!("+!($##'#&!''!#''&*&)"%%(&'!($*&'$*#"!#%&&*"$')#%*((
@r5660
TTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCAT
+
<4'!>+-,(0E3/:<")(*%HB#47$C5=;4!/4'6;9,?&*'*+)C'CA9*-'9=
@r5661
GGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCAT
+
@$@)3H(-F;EA2.:?(2)?8/.E221G&&F+B(8%36#D3423"D)7GD*3EAG.C'4$633H.+
@r5662
ATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAATCAGGCGTAAAAATTGCCATCCCAACAGCATTGCATNTTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGNAAAGAGATTCTTGGCGGAGAAACCATAAGTGCATCTACTCG
+
="4>-H9.,74=4.,:31'HH1?-/<'++5E)2@B(@;@.(G<0<EA+BDH#%></A<:"A:?(F3)@;4D"@,DG8+@<,?*%FC%''-.@"7@8H233$B&;(2!20?7/1G1)%@,=/9/)($6/1:'3<55*ECDF@#2C=*CE(!((23"#=6*5<)4,4F-*+%(%&EAD*.CH$/2,
@r5663
GGNTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCG
+
*%#'*+!%()+&)""$$#&(!*$"&))'+%&+)$%'&$%(!"&$'%(#$)$$(""()
@r5664
CTGTTAAAATNTCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGT
+
-;CF1(=79D#>#,9/:%.<20$(%.3BD!+7<5%,A(07='8G;
@r5665
GACGGAAGANACCGGACGTTATGATTTAGCGTGGAAAGATTTGTG
+
+G&<H><2G?B1/0<)G3":0:+9;&&;;8DE:'=3@""4%$9E>
@r5666
GACAGACAAAAAANATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCNATGG
+
3*3+6AH+0H<F&G%8;9$3;4*4F?63*1'F5GH6F1!$&8=0B<%F7'"6C/B@9>-D343$E-(@H'()BC&,6H72F8!/356H,;@D-G>$H#80<.H!0*972#658'C?!G$0GA%+733)->;;!F5A&DEH9EF!D9(C=FC<!E3<-$<A9B.>32D07>1:2-EF%5+>6">&3H)23)4
@r5667
CCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACAAAGGATCTCTCTTTTAA
+
,877",'8-9?CF<-E6D5>C5ED>$'!+9A+='@0,3BF/<C=4BDC(47)CF=!!*'E>'GF*'>68!BC5AB
@r5668
CGGCGAGCGCGGCTTTTCCGCGNCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGNTTCCGCTGACGTTTCGCGGA
+
=%-9)H&:1!E'C1D=7(1#?$$@&:,7>84C:B1<@G<<-6F='"!%7C*3*!/)20CEC)'26%>/:)"'#!?<:=$0::&D2C74>/:2*!)#:.5&.$"0>&+&/@;$3;!E>@==)?@:D4?3;=8
@r5669
TTAACAAAATAATCATCCNTGCGCAGATTCCAGATGTCGTCTTCTTTCTTATACGCAGCCTNTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGA
+
GF-AA0'2%H)H520,01$+?4G"AFA6:9+<4H3E5")-1#D2$;&7#>19>E7@B26>H$B7409@D5H>">%#G3DE/F;4:):"</H46C"#
@r5670
GGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTTCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAANACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATG
+
.+44<!31=(E>=,CA$D+1F@:/B7*':60+%<D54/&/$($1:!8-C>+*=0."!&=,"EF,86%,G=A5A!/A;<<'2:-)C="B./<1*+E2$!3)#/11<GA8H9?;#$079)E26=@GC'(;FAH3>*4*'$<BC&D>H01%??.F5&B3%"%@%&37(9-=@?#6$>(5'";G=)*?A4,"&>7#A98,)5"*:&:&=%#<8*.6"@::'&964."6F-E&:6->8$8(*A;+-9/<2.E"
@r5671
CGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACAC
+
4F"!8&'EA)A24H.8:-$/'%,FG?"06';.(&(@1>B&H0%&B@5A47H%+.;?>@%;46(!D)9D-3@:;-$>#4E,B+?081EG,
@r5672
CAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTCACGTCTTTTCTTTCACGACTT
+
1<299HBB%,B>8FE,G';5!##0A."$B:9,7A040B*D+3:/,G15)+G9!%(:1)8/?<+%?+:G$D(0#G<$F9#4'+)EF@!<=:@*F.4(3$B9$,B=B9
@r5673
ATCATTTCCAGCTTTCGTGAAAGGGATGCGGCTAACGAATGAAATTCTTCGTC
+
+$(($&$%!$+$&*#(*%#!#'$)'#!%&!$(*"&(##%+)""*)+()(*)*)
@r5674
GTTCAGAAAGCGTGACGGTCACANCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGNGGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGNAATGTTGACCTTGCCTGCA
+
55B>H<;8DHA!5:<FF',0$7G0.-+9F:?:"E!&G;?2@BE/7'8<$3-@+3G+=#5=02/48@.48CGGD)"'893G,1F62DHF?4AB5F/>+1*$.H)'F(&$?;A8=H<&C.3#.1(B,3"@;&,')%$;?2!'&=<8G!1(@,C!D7)
@r5675
CTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCAC
+
H=>%#C)*"GH73>;B12%D!D72B55+=1F3B<%'G,)$4'*H#<+):89+89.B<:D!/HB)"7B?B2"2*(?*(E"@$"=+;2G>*B,24A0'#7E/'/;&(F;-.<(*F(2>7B(9B-7#1#@/-)1&%.,=B?%:-%1:G-"F*>;8(*7.+->'@8.DE0.=?<#F&?F:(-H$(4'22=/.$C;BB'':>.D
@r5676
GCGATNCTGANCNANGCCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTA
+
&&%)($""''&'"*%#'+)#'+&"&$$$"%"($&))+&!*"%&'*($#&&%'
@r5677
TGCNTNAAGTNCNCANTCGCNATGCATTGCCTGCTCTGCCGCTTCACG
+
(#%#)$)#")"%%('!'(**!+'("(#*!"**!("$%$%%!$"#")(+
@r5678
CCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAA
+
%(0,+-!C4*'A<<29B;F7(#=)',.B(A%#:6=F$!6HD&/4*B@@!GFA76C&=;>.*1=D,:@"/;%B8;-1A":D&7AB79&0D*B4<";<6"D1)(;/D=!?,-6)$@)F:9=$=(4$)679.?=
@r5679
TCCGGGAGCACTTTTACTATTAANTGAAAAGTGGAAATCTGNCAATTCTGGC
+
71.:G!2'BE:11(+C)=D+!*>>D2?7@A"'"D4;2.(..?<&C;%++F;.
@r5680
GGCCTTGAACTGAAATCCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCC
+
;*::F-,(-EEC5,?9@((74@G!C%*4H9#<8#A;-)D7'EF79>H-A<?0HC;'G956;(;6?538B&B#;B$EC7H4,#G,H&>EG2?
@r5681
CTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACT
+
%C5G??$-=*@=&,12*>$!(&A%BC5@/&#&6B9;B-+@#:.,GG+GG$>B6?#?+55G2A(*49F<18<3@<A.:*E:!)
@r5682
CATCCATCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAA
+
B*)8127:5'(3!32/672'4883%F%*"6FB9!7D85&;<F#58#<'%E*<*EB-+9%D&+BB"+!4!#-72"?=?(+*:&+)$8&.&6H"6;H#)?H0.C2<,""5=<H&E65H$+21#+>3!'"#*"4.B(+)0G:8&%B,099A-+HC2(4G@G/
@r5683
ATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAG
+
C+0'>)D2C)/)E9?+'D&(A:EH9B.&,3)4)-='C*;=?7)@C69,F@A?(@2;'0.2%
@r5684
AAANNATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTNCATACG
+
(*%""+'$)!+!*$$*%+%&$)&&%#+*&$(#"*+%))#+&+*!$%#!$)!%%""''+*&"&'
@r5685
NCGCCAAAAAGNCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGT
+
!:@1<27:*92>68,+*2<$/6$4&F)>3;4DE=A5@:?0<,(98#>D"-(/F6D%%-H4)AD
@r5686
ATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTNGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCTTCGCTCAGTGTTGATCTGATTAANTTGGCTGACGCCGCCTTGCCCTCGTCTATNTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCA
+
-21F1H<%069,#/'"5/-<7':E%6F!9@.-5:-982"8A8::,3-E6#>/.687A4:CF*>8<+@-6-)72*(FE=E50'7/4%&&0$E;20#/G'0?4>-+"-+/8G6'GF%:"(*<0DF6$G6<:%E#'81GF%E089#$#"9$&/F;F'-3=".(@<0#H(BD#A,+*%F8;HAF(0'99@0&.'137<-5.H)45!2"1AG4$&1F+*%7H%:+%96A,73F*7=4.H1>>:68,&EG0436:G7?D/B6$.F.%,H0BF%)H3?8FH-(G$'8D$963*4:358D)4(CE"--'*?%=5)BG6D#$,6E:@F*2<F"D/F,,6246;C"'8@4<%0.4#=
@r5687
TTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATACGGCTTACCGCAGCAAAAATAAAGGGAAAGNTCAATAAACCTGT
+
=C!,?"#2E&A%A1$9$4)G+320$87;"G=F9%A:B3#*1D.<*(8*+A)D"D9<&C8/7+*@>@2<.=)#G%54;?)(F&@#A+F"A>-2?=3@?/C*E,+4H#
@r5688
TTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCT
+
+*+"(&+*#*+'"++'$*$$''%!'"%&*%!##)(%$#$&$!!$$%$)$#$%&)(('*)&%&(%#$)#%#**&$'"#
@r5689
ATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGANTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGANATTTCTAAA
+
2?=+/*%>8(A5).G,<FF@(2D6"=*+*@"61C*HD&8-D/*C$'<9)-=$?9(H1*1#G)5)86#HE@@4#%-.AFH.-),8CA.$#G/*/1"AHC'(?A&6)%D<(<58;=?/8*!6>(
@r5690
ACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGNCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCC
+
<-?:A,GHGDD8%)1$=/2</E8>@G*<CC=-))?")E<&/7,<:*%EH:<?*1?$<D#,<<7,E5HE41$C$6@-**4:4<3@2":
@r5691
GATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTG
+
+*45!<%5)!D*6&EC16(,)E)-6>A0FB26"%B@9%7?D@<739>;",G.FH03
@r5692
CCCCGTCAGGCTGACATCACGGNTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGANACAATGGCCACGAAGGG
+
;(#?F<(22,6)C#7@(5G9,C$+0#1+-C!+34H>:5)"3CBC'01(8#0"F46G1*GE+G$@>98;&:/,27?>/.)6?8F@:F;90C6@=#=C'5.*E@ACEG+7(+
@r5693
TATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTT
+
4?"D"6%3045G:A)/#AC@6H8F8'?F>"$F<1&@G@4D95(9:-98+F4BHBG1'!+C@6-54",#3C
@r5694
GGACAATCTGGCATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATG
+
?B(57>*:;B3/:FDH/H5*7E0:3>$:?3,42ABC&=/.0+1@$-&C3D)+1A!
@r5695
NTCCCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAA
+
.2"-&7E"E4F2-<6FF/>197!G-9$2A#-356.C!:&G:"2H#6).DF@C>7/4939=B6,2*B?18>>8F,#38#$:;11F=+:A0"4D30
@r5696
TTTATTTGGGGNAGAGGGAAGTCAAGAAAGAACTAACCNTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAANCATTCAGGAACGCAACCGCAGCTTAGACCAAAAC
+
16@.A*4/:->'>(#=$#>!C;D+0832</8)FC)2$:$);!><</F$G:-/(-E@@@;#6-52=#5+.)?'A3@,*359=1H>>G38?=#=75315"-E&54;H$<+"=B;C!"BC8#/=%9H/542-,?C&-+B8+*8=,!B!&E%<&57B3BF0?:*0
@r5697
CAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTANACGCATCCTGCTGGTTGACTGGCCTA
+
<D5G=:+8=68'5?F4&>:,C*$/8*21&D%3=<;*#9D>"18+E(<4?D#.%B6$5&H*)/8:A>?/98#00A=09-==>);%@>6'A8<HF)?&.E7D'(-6+($>%<,126G@G3-C:0#CA2GF/'<$H6')@>?A.F#96H/=2%77+:B85@4A..%*$@E=&(&F?#?3/2)G8H*:<FB+F?H6/+-&E'%A<85(&H1G?E1))HG2$-#*!5.B6A"E4/:&26E;?%<8@#&*!8;AA<5'.7E,+45F*A13+@A&2'4/B/HBBE?<1@$&C2++-B0*E%8*2!6G!"E
@r5698
ATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTATGCGATGTACTNG
+
+2?(<7%D@3#DA1(C/?>$+>A&>A=>GC5?(F6=AH+:C6*B>()1"3=;=0@EBA4D7"H+-9*@-/<G!>%E&=2'2+&F,$<>14?C=C3+%-G&?13EA%4DH"C'9*3+20(42
@r5699
ACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATT
+
G=C70'E-F8/9.!EC$71)?&'&/)H:F>&=#7*2@:8/C>?7DD)2*D='(><
@r5700
TCTGCTAACACGTTTCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTAGCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATATGCCGGAGCGGA
+
0!5'/35/1-6)C,>D'H>=;%%F-"2C2?7+$2B*-$A/@9B83?9;:F(/7.A0F-,<;?>2)>?>F"'5;.5/(.'72G2#@DF8"6E)F9?A//",'<EG,EE*;!F9E96#<@DE#=@;9=7144B>(F,7;>"E93'+C+34C247761+>C;9G-1"80&"-./6G!+5@>HCBC-%55.,6/(=:5*F?F%0EB+CC*50B21EA(69/"'F&G*
@r5701
NCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCCGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCA
+
'/*@:01?3C4/(25=@7@FH+G$446$>'@=7@F1,'1#?D>2DH#="2$&C=!$0);6%:3'!$!,$)7,.H*,#+E<2-%#:>?8<B(43=B(+9/4,33#)$!>5?"!3:H.'.,<%$0H+#3B6%6@D/;4H?/33+#''>0<.00"%3@%0F%0>??<;D-C7'@">>77&E5$=@<H%F0-D&#5BE;:1%/857.5"$H2#B%:-99#C5>2-;@H!G)61G?.!#;%G'F/HG!30940-0A&C!=(H81423/9.%;6G1;F,D98"69'<<<*#6((G(-:6376H%C-%D5
@r5702
NGCACTTGCAGTACCTTTGCCTTAGAATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCAT
+
%1$61+#=G*)H;.*;1@D*C36*-$*:&(-+*66F,G8&#0'?53:8;EA+7.48<8D**!:8!G*=)59.)DGFF7'$%>..)!
@r5703
NATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGTAAAACCGNCAACCTGTAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTAC
+
*;,6"/D<%;$B1)H3.)#&3(=;E#,>E862</>,2C;9E!73-H34#(&@';+F"H)@3,C7+1"=/;<GF?CC3($3#2;0D?.48*$!3>?:%:GB;BEB1CA)BA'CGD37(E./$C"GE"E2H7;,-9B2C#4>/0+;/'(F%E4&6*'!93'A5F:C.7!?('<)E-00$E,.96&;(<6CDGG?F0)A(
@r5704
GCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCNCCCTCAGCGTACCGTT
+
'BBFD9H/,856&8E;)$$F$CB#H>56<=,>-<,(##8%0(<=6C$.82@@#*(-6>(
@r5705
CGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCC
+
.,&;'6,;B$3,$BEEG;C)A7=6!1C*76CC80;9D"8>/4::46"
@r5706
ATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTC
+
(GC0>:%126$0:.<.;E6')CA><GG+5.!'1!7)*627F%CG6#80/&GE;F36H5';$#=0*?C4*7)7
@r5707
GGGATTTTTTATATCTGCACAACAGGTAAGAGCANTNAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGT
+
8@1;B$0*$('!#714F2FB%>%)-!0/!F?$??!<3CD+E!0,:FC/;$,+AGH6BD$"-A3(F(?E-!08(#?H,16&HF%,F0(8<>98
@r5708
TTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGNAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTACATTATCGTTTTTATCGT
+
;8'*67!(1-*E(BE:)G%!+(AE++-0(!1H0?)H?,D=DGD<5<D/?5.</>3;-%:*9!3G4;*<H),*:**44%%12-('&<36GHG.8;'<.A9(>+;!8?0H2+764!>@;AC0&))E*@3#
@r5709
AGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGGGGGTTATCCAANAGGA
+
-7,D.-93/8:1C"/9=,@D3'D;<EA1,7DC**&1<C>4E12@E#$1@'1'3%A@*$'90H?A)&,*?6&H4E,*&F$@!'F27G2)@,F".*,94;,E564"1"."!<8=
@r5710
NAGCTAACTGACAGGAGAATCCAGATGGATGCACAGACACGCCGCCGCGAACGTNGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTNGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAA
+
"H2!+:F(>DD9<"0;@6>BD$(=+-2C7@+D+;)1G5*1"9B<-&G9&,-.9%&D1?$>6<9,+B*?%$-@D))#("@=)1!)'582,A'#/G+@9<D?-99*A+D%.>$6(&1'%36<&63&&?@".@>&<,+#2A2H?:<$1"CCD='0'29()'-3:E%5*8A@9:88A6$>%BC*=A#9<>"%9(GDCF+%-6@%C;?/6#%-6,5C5"<D6>1AF<H1DC,'&)4.;>C%5HHE$<=,=-""7*C/@6B+CB7$@3-!?/3:>,'"3.,4@H
@r5711
TAAAATGGTATGCCGANAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACG
+
4@<7,61)B++"2A2C:H'H!.7;:-<'.8H$$(7:H&!7+(,'%**)9).:7>""GF<($GH38B<(=+A53-$?#*,#)BC='A:02%/3=D$729G7D-4?0",!(-:+ED>0A)
@r5712
TTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTAC
+
%H/=".1@DC926+&!.;F"";-"&>1367+>.98*0>@:F;!!3>&-'9;%,"52="B1-6>@%H'?6#,0<9?7<,+8)G4AE$*:
@r5713
CAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACCCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCG
+
-E)%5;+B:'&1=40#9%.A?:0.A=9/.CGHD$9HC(8'"D>71->=%37)295'-/:<,"H!<H-2,<0!G;F.&0,;G*>$&7A+3H!AG?.;&89G$->8?D3G.0*!&/!168,=86C4&7B755'6BF/'
@r5714
GCGNTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCC
+
/C)2C(:<.-=,2327GF3-;F*$%++FH2)+.,)/!=0;,F!$@)),9$9&&*66?$.HD:)+&46E()3G%ACD4$,8:+/D=<5%-?,!9<<@8;-$,/@>98C6%3@FAE;!$<C/G$<
@r5715
CAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGCAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGATGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGT
+
@)ACG:"%?681G9<$A!:'3$(4>7(C*>&5.C-E:'+&0<H=+0F0%B53":@>3*@$H7:+C9@$2%$(<.E08535>6230>@>C2*B1CG(@$#=,@:3$#)0&$/=E?$'H!.8G1>4D@D>$6+#+2-$1E;E+47BD:4H;69:''3+$>(!+DD)1B/B=@/-EG%;26&!;C5(;<A$&-#;(?@"'#=1C5'196E-!/=4A#;F*=F0B+",D8!A)B*=22%8%:#-3D(#
@r5716
GGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTANACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAA
+
*.A#*HG!E..3=A!,;*F4+7"*F$0%A/C384=0"H.=)B27@B(==#*46"3D+3@8H?>8+C*4*G!)@:>@A0B0.)D'($A5!%0%G<-E?"C086/;@D%G?'+2*D&F.A;!2E$@D7#+&?*AC/$H@A"H1?190DF>
@r5717
GTGGCAANGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATNGAGAAC
+
'*+'%##$!(''&$+!('('())"$))$)$#$$))$&%)")&"&+*!"$+())(!#""#!(&(%+#*+)!*+)()")*"%
@r5718
GNAATTATTTTATTGTCATATTGTATCATGCTATATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAATTATTCTCCTGTCTTCATCNAATAAAGAGTCGAATGATGTTGGCGAAAT
+
,(C=2;/DF>:1@C=7*)C7!"A=&G@/,/=<+?&$49)A;@DEC6H!=6*6/9:EG-7%@<:%C@+%(D@C"5>1<G=9>D#61>%A3132#&+5?G70<5)&5'7<929@)8#!971=++;G8
@r5719
ATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCANCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATG
+
*$+)'#'%+""#+''(%+($'*#)&*)'!$#')#!$!)#!*+$'$&''()%$)"!##*'#+*##+#*!'#$)#%)&&($"+%(!*$+!+$!(&*$#(*!"%")#+"'"$))(&%&"+
@r5720
AAACAAGCGATCGAAAATATCGCTTTGGGATTCTTGACTCGATAAGTCAATTATTTTCAGAGAAAAAATATTCATTCTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCG
+
)C)C==;>;6D.=;4:6'+D(?C97A@1&6=-.EG2<#G)/@30$#C>=7A>+!G2@,#AA(.GE07.,.H!%H=$),EA6160"9,<?%(7A'+.?#C9+;/'!+7$)*=DACG3;)A*#<C4<"<8%9F1,(">B;FE9B+.C6
@r5721
GAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGNCGGTTG
+
3:&<G"C)*&07>-2.3'09/1A32,C99=++<2'03)79=$.90C#F=EB6/(,#$-9;++B8;BHCG2:
@r5722
ATTCCAGGCATTGGCTTTAGCCGCTACGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAA
+
5"242H%+7*1G9C6H(25")H.ED:H#$)/%6.D6B,8"%#(<1#39H&A>G6((#8)@)F7-C2A?0?<0-3'"!
@r5723
TGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAAATAATTGNCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATNTCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTTGCGTCCAC
+
00A:1HB=&.!E.%+FF2=0&-.F5;5>$/:;3!F:9F2><B98HD8!/8@;C?&"6%GBD5-.>-H/H'1(/B1=<C'!<GG%9E%B;=(<ED<7;5+A!('<8";.-%<>*!&=:0ED:.)):>6:&?DCF=/&+F02B@*)6>.H&!F<H(00H"5C;'AA.6:B:7<+89.=A*%C6H!
@r5724
GTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTNTTTGTAAACGCACCGCCCTTATTTCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCNCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCNACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCC
+
0*2AGG8@A18BA?%)A5?'/C*1%D3-C4B>+.=?:D9+E=4H$240C-?F3A9)@"6F6@0?9,C#A!/3EF8--)&:%"G"<A-(D?>A4:>$%@6"'..@G9<%$E;5.%E;"-2H;%:.8=98A+%/040=F2@.D,*9C1%'8G+A1BE-6,DF85DB(%5!*CE<9196*E%48F88;C1>><;A'@@*A<??
@r5725
ATGTCCGGCGNCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGTTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCAC
+
!/2F2"(=4%@*-:,E@?#+!%9%'0%<*+-;>($>$&%(;(!HH=0D4>@,**'$#&5"DF-?2%:);$/%A!8)'.C=</3?G*CB1-0C"="8G2+%FD<,81#?E%0/H%A&&==5+:
@r5726
CTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATGAGTTCCATATTT
+
$.2=E<=@6,-%7=(9?/#=25/:C,?7>()?<<$@:4$;<?+CF20H);?,E?,&=,",
@r5727
NGTTGTCGAATCCAATCGTATCCAGTTTGNTCATCAGGTTCGTGTNGCANCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCCTCAATTTTTTC
+
7("(>1HG:;C*&9B1>!'>$8H!;-%5D8/C,H*A,"7=>0:$2=:99*!4'"G!"*&HC76>/4D2A2:3/;&>B((?>')&89:C)1+F(5@'E:7&A:,;$!
@r5728
AACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCNGGCGAACGC
+
#)A":<E9!835F7AB&"C.'8F7B?2%8B9<H(/!A/'"%"0,D>)E+.@8/9@"6&99
@r5729
AGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGNCTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCC
+
0%--@D!=*%7/G$%/*.$'>1F;(%6#C01***E%+(7;7CE-7()"G5561388#&")A)+)5F+36E"<!%:B480'!G?H%3?#7/<:D"F",@4A>:H>H4'69.?;D,C6)83,*C1D6
@r5730
GATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCT
+
%$,5;;020(CA$5',<3$G'GBF);=:8B,G=%F1F-@88#%$DCF2"2:'B/2>$DHDH':)<213;.3<.:C/:/);9"F2">83.C3<F=*B(4$9"8E;'(@8#5D/=)&,036=9:5?506;/=@+6!<D'917"FDF0:,(--7@2#)=#50D60!>?#?)A9B#7A9'B%
@r5731
TNTNCGCCCGTGTATTCAGCNCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGNNTCTCCAGTGCATCCA
+
*&&+'')&!)(%!&%%!%"#&&+#%++$(*+#+!%*)#)%'%"*%$+*"$!####"(%#$'&'*%"$")#%+(#*#&*%"()#'!%#+%)%'&%"$%$(&)!+#%**(&)+'+($+$)+!($"#
@r5732
AGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGG
+
'E2=C/<!$7!9#?C>3&6,7.,%0FC9%"/G2B"+)=FF$:6:.1
@r5733
TTGNAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAATACAAT
+
6$0B6E*3EB@2;7)'#=(CE205>5E0*4<*"&$>6907(9?.@4!>6<.3.$*0-;(**$&AF.#B9D='A39""D'!7&EC12-(#C05D#0*&%H%6G2FH<;?7H.*7.1729F1*%3.B#7(E+*"A.;E#:=&%1,)&F?D(!7;9E"<(7163$
@r5734
GTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGA
+
7*:5?/:+?96*15>-!,&9.4?7:$H8?159>,*E&0C6%7939$9@F.E=+>E#G&H?82B</7,4#&B?6;*/&?A
@r5735
GCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTNCATCAGGACGTAGCCAGACGGAACGNTATCTNATGGCCACGGGATCGGCNCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGNTGCACCATATTCC
+
20497<E'+,D;;2@+"!B7))FD>#=5."F:"BA<;<$"#'>8+2+-;/$;,>=E0'(;D59&??,21;&)<"$F.&(CC27E(;:'?8)46:'C.5B=''ED@!@7E-C($5B!.A,":&:02"F5!7*7;B$3<#4D!@<HE00EC%6"3<#B>18/806%8A+C;/;E
@r5736
CACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGT
+
4*)&=;:%;=4+36G(24+:,B+0)H;'>D9'?1=$E-1)./%6B@9E(+&<:!!$?)/85":4++18@%&67-5,&48*&9/):0!54+)6%'H=1G(?.6H;.<'!;$8(AB=*:"H@F$F*3-:$6&*!6EB<D-:,1A19.
@r5737
ANGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATG
+
'!-DE3B2'3428FH;H"B;BF"'D1:4+H*91A6!%**3.%8"7;:22GA*@%$#'
@r5738
CTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCANCACCGGGGCGTT
+
*=D2@EH;%B)E5A*-*()1<HC69H-(A+'B2C2$D8EH&0>?@$8&+-*8:=<DH*.?EA*#,FE5@!0E4&7>G4D'5"<)#$;,&"20-,?05/!GD2B=!%3@;A<5*@1824FC(6@>1:3:%3A*$3D<>.#C"5'"928E158."=*=0FDA,:<(1*)5*;
@r5739
CGGTGCCCCCTGCANCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTT
+
40:&%F7C?48!/D),4='B<H()1)/857&H);A4@4(9;H!8*!>;=!=4(+#!2AC=7/9?65H2*C#<8%A$H=8-(B&6)#/A"3
@r5740
TCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATC
+
G+@>$+F24:@@<4$&2!B;+2?##<?="#=9<+942@DF5"9)@--+GCG%HF52$*"%G?G%.*)F'0.?,"F#A?*90;%+>2G8&/?(&D/(?.GG"2%3!+=*EGA4B>'.7*9B,#0+4@H3F@6(>=($+6:ABC
@r5741
GAGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCC
+
*"1,<4>4>G8@%2,5.A-4<:7!E;'::#6/3+72<CBB?D<H9/)%0
@r5742
TAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGANAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGA
+
28!7G;5EE0*C/A6:H>4E"@&?:(?E>A,5"D@&C0$>DDE(7EF&@531""$88."@)>1E9,24@.30=G>F,*4(;F5%=7ED8G*$*,9B&AF3+/>;A#==.FBF*
@r5743
NTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATAGGCGCGACAAGTT
+
#=>7+<7.8?.#"($!GH(H5*08:&CG)+2C?:"/)FA816.>&!F.9.(6>%&%@1;3H8>
@r5744
CACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCCGCTGGAANGTGAAACCCGG
+
-C:/8+6@7>)+8@!07F3"-)0C';&D8=;!57<!-&//%*'8H(<*EE6C!3<=.57*7>*67E-(0"C7
@r5745
AAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGTCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACA
+
'C2.%*#-3,34#E+<=#85'@2%1!)+/3==.$("0&2'@H*@*"(1=8D3F&)8G5+#3&!/9>*7F'5:.)8<@41"-;%C!<='83?3E#;4#37&D;#&+G44*&')5'+A06DA%2BD(A6H)7G.&A,$G$E08
@r5746
GCATCCATTNCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTNCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAA
+
?<.F$&E&@A9-&:68<-=&3'2E.>,H,'68E=<H</!*/%90%305G(@=ED0(3?;80A=.+$5;C:F,0=".60=@36,:>4*:6;5+%+&H,36B84A8C8@E5
@r5747
AGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCAT
+
5&*"!99!!?1/H6'3%&G?*/CA:C?&D%""&55D,?=#.-2&=ED/$0:!-A%#)283?00C)
@r5748
GGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCG
+
/$-+H,5=!B/#66,F@;E,2FA@+-&CH/=EF"E+#@&15&!2'D1!=E3469$*;8&E=/<1:27#8,/5,
@r5749
ACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACNGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCC
+
=6D=.$HA@5GB'$%1>8(9*&!H(6-"169)%E4E$&ACHE-(1?%7!!$'9!>.2(/;3*>?!+8.3::#A-3%;($44'!'3<2H>89AG/;81.GHD4967G45E/3@#GH:,4/GFA15&>A0CG=C/4C1.6:'>:9F:13E=(F43>*.,!0AB(-,AG&BH=++#%@31,<(-1/B-)&>23,@D7*E8*=')*$FA)??%#5&"E))#*(&=/81*G2BB;79C29B,::?@@>8>:';=;E<!>9(B1)-/+B4'!)6"4%0:&@1*H1=7@#G.CA#%?(3&&3.4<&%DA'B13A1;86$@/%'0H!B%G7",/
@r5750
GAAGCCATCACCCCCACACTCTCCNTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCANCGTAAACGTACCA
+
2>&"C!/F8"<7A7G(6!%/7<G/<D7;@+A5&C8&5?'C;E'&/')=!(=CF9&"F"A?(C..=7!$:"9B#;("D+0)G()0B)=@FAF#8+GCE1'F+./BD(')"H20:C4*A:D$''(G.<9&-B)00!6"8/*D231A
@r5751
AGAAANCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACNGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCNTCATCGACCACCTCCGGAGAACAGGCCACCATNANGCATCTGTGTCTGAATTTCATCATGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAA
+
.G>1@,86"?;G;2;@5-94F5&$0@GC.*H8<@+#<&/H4@7"6-(F,$%H=F1=8A?5C+",/$($8:29$8A!=?':E.(->(!99:1?(.?&B/./80<G1/61+7;D<:(53/,,0035,54$2@G/$-1>#G-(0,&1+7,CA@H%C513(..!B1;")--66":EA3">'<259'C)%%C8-2.-C':!$;+:*(DG"2@AF">A!$F?DF&6&*$.G?(7:*C3D.@H9./H3-32>-6$9/?><D919>8<65(G&!!+"<)9!#;&:0<$#"5<0$0:H*'#/+H63C;08&F;-%*4BC3,04*>D4@%;EC%D&(&7)AE(H)+/$:H(F73E4/"D@:+>?#E?CE>78>*=90.26'*.@!C+-F%,,G-;>5,,1;#$5106?4>=:A=*+F@(><7-00GA<":4='=(,:,=CA?F>
@r5752
TGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCAT
+
.AE%),+:&H<*,>A$$6C'5-@-38@=7H&BG-77!0?@@;(<?9>95$;5-:B*D:.=;16)2<G6?%H/#2?,*$6@'F*;G-B5!."F%2:<4/2<D%.*2>;;?,<'5($
@r5753
TTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGNTTGGTCAGATCT
+
15!<516%;@=>77%=BC0GAG*::H>452??0<D!277;7+B%1G)>DE7:3;/D?:=?9#."FC3$>"4
@r5754
GGNAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGAGCCGGTTC
+
G@)G.5B,G8;:9"4@(-66/;*50B.+GH)F<D.7*E<D$7("51C4?)>;;$B@8'G17DC"-EE&E:(9%B(BD/E(;"9@59#C@)<E";4!0A4$#H?<86,22)/2$91(.E.'B1H7-'%+=ABC-G",$'3;4D+0#:2(=15)'3;E7#*95=AF%!0.-?,$G
@r5755
TTGCCACCCGTTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCAGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGC
+
A6$5-*"C<%C!C??H5=49'=/,*"/15H'G3/A+!HG4A:$/3,:.A51.*(8.9$@H3H5?%9"1#9@4%D*'%,>.8@7*29;A8=CF&0''"C0-
@r5756
GACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCG
+
,&0"DDA>$)'"5B8GFHF,!9@+)D:#(!0C4;42#!6!"29>)1:A%;28'1@1*:%=61/#3C
@r5757
CTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCCGTAATGTCCGGCATCCCACTGAGCAGACGAGCGTTCCGCACGAGATACATGGTA
+
C"&52>='1)3E#99A.//=+5?H-;5<B56<$16G@AE*9F;&0H;"64(#,,#B@;$EFH&@@(%@11D.,<8DH0H%BFH6'@<)+6%C90#,3,$HH+;+!G;H
@r5758
GGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAGACTCTTTCCATGCCG
+
/@>=0-329&5!9=?3<;B3>7/$&:4(DC,A488'F)4.8$>=A."32%G$(G2!4(,6##2H162.0&AGE5DA>0.@@("')3A"#1A;
@r5759
ATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAAAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAG
+
8H78:F(*A5C?-305/A/G/"62(GF$?EC4G0(F=<.;*8ED8/D/3&(#-93$BG5*1*39:6HC329"D>,3'!,FD?CA:-0?'048D#*-%F+11@93@0<(,4'#@(?%2:.4%H5;+/5)1127876EBF$4+;3@57#:)&C3CE0>G"G&3=2?44"<*#.
@r5760
CAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCACCGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGGTGGC
+
?7!#6G%-@&6'*+2).9C=//1!,$*=GB;>;2(E3A#"&.8ABF2@<.@<&BC/67.G<#<"$BG$=@%F?481#C-$;?8!;CG0+1"C90F8-F
@r5761
TGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGC
+
B6<83(3D=:40B7D0:>93<('./H3';0:,%-:/7$@;>/94!0%"!4!17!',B94F)4DF(BE(G306AB?)3:!HG#7)==,F(D03GEH%(7A7<$/0#)?">.+'H%*!#'
@r5762
GGCTNCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTGTGAAGTTGTNTTTACGTTAAGTTGANGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACNTGGTTTGANGNCCTCCACGCACGTTGTGATATGTAGATGATAATCATNATCACTTTACGGGTCCT
+
$")+%!&(&&!!')&+&')%+&((("*!+"+&'!*#$*&)!&++('&+&(+!*"!"+!'+'*!+*&$"#*+!$%#'+$)(')$$'+!#%&)+*+(&*$+($&%+!&!(#')+*)$)+*#*#!'%()")&%($)&"+%#)%)&!&'"*)+'%!$!*%$!"%&&"*!)+&!&'###*!+&)%$!*'$)$"#'+"%(+!%!$($)++*#&#%"*&$$&'('(**+&%))$###!)(%!')')&!%#!&$+'"$!"$!!#(("*"!%%'*$%$%+"*#+%)#!(#('(#$*)$*'*+!%#('%"+"'")!&(
@r5763
AACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATA
+
4GC(BB;&>-9.A/A"8,@CDE,'8&,&<94F),>@'06:1@4-%/)/.7BG(+<-1<1E*;%:!=).8=(G>9("7%5BG-9F<>%.#0.H94#).#>B<$9*7+<'(,/,=8DE*GFB<D'6G7=C5C,"(
@r5764
TTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATG
+
=104A65'7D*'))-%83E.G6+$%57AE(A$=A@DBH$3?G9
@r5765
AGCCGCTCGAAAGAAGGATGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGAC
+
E;&BH5@>B)#H,+<3B7<=#%240FG#134/"$)9FA;E."%>::E3-,).:>$F63E1!68=C20>*D5$<(@"F>0"FE3516:@:&A$31#>;=@"?80%?&H&;-7H.C#6<1..B;5:+2
@r5766
ANTTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGANCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGC
+
%"(D:7'%F#D7HF37-&0E52654D&&7-4>0(A>?4DB$&38D'4:B380!/H'47<%-<&%=3+F#,:)"$=#"B912)*>*B(,0;+7&-6H<C?+A&4HH
@r5767
CTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAA
+
<HC0?#(E<(!3="B;F0-43<%<A#F7@<!6)27><$"C-"
@r5768
ACCAACGCTGCCTCAATTGCTCTGAATGATTCCAGAGACACCTTATGTTCTATACATGCAANTACAACNTCAGGGTAACTC
+
?:6(4A0(0?*>DH+'?!9'H2$?%7)$@>-/G$-BF,%(>:!BA(2='&F/',?7$9E4.+1*#$*A!=9F//>>#;CH&
@r5769
TGCANCGATCGCCNGAAGNCACCTTCACGCTGGACTGTTTCGGCTNTTTCAGCGTCGCNTCATAATCCTTTTTCGCCGCCGCCATCAG
+
)*&*&(#*&*&''(%&&+*!'$)%*''&$#%%#$&!(&)*&)+%'#"+"&%$'$)!"(*&""'%$#((&'!!!*#!$(&(#+*(#%%(
@r5770
NNTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTGGGTAGGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGG
+
!!''*+"&#%(*$+!%+!)$'!#'))%"!"*+"""%(#+$%)('++'#%*#!&))%'&+%%&*#)'($%#)!+&$%$')++")!)'!**'##)"!)%!"%$$)(')%##(#))*''+)+"%&(#'#($##!)$'#%"!"$")!!'&%&')'!($$!$'''!+&#)+%+!'''%
@r5771
AACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTNATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAA
+
17/!&<%&!B6,,C'&,%72=,5H(G7):F?##2C)D0:97@$+=#A3:-D9D;?'>%$#(,@'$13/@@@<;&%+".5E*B;/-9?0>E=>5+.,"/"0'C$0)!.A*6*9GE21=#*0&D9:#?4D,C?F86HD@'@43
@r5772
CGGTGTCATGCTTCTCCAGTGCNTCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCNGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGTGGCACCGC
+
)8$#%,%*D?.H>!)=(1'712/EF4&-?AC;<.>4C"1A1-C82E*@!9=+B".+/C;6F-F4E+H#)+H8%/*748&@.!"8=:085@+9+'<!%+#E@@(7&2=2&:'0)>99$#:70E&*?:434>"'B-D.),G>2815F,G*$!9B8$8&6E-*@?$@G)4.9<.
@r5773
TGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGNTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCA
+
.1?3G!<2'B'69F"<8#C2.->0%+6!;G"C3.8#!2-,9F:&AA)!82-4H&(133)*&E=E=!:,:6<'#*4F2".DGBA-;EE4#8DC("1E43<7(-.ABC234A&'D@F&2:#AB5B=.-
@r5774
NGCTGCNNNCTNATNTTGAATGNGNGGTCGTTGACGACGACATGGCTCGATTGGCGCGACA
+
)&$!))"#%&%&%'"$**%#*(!"!"+#!+'$(%)'""'((#"!(##(#++!)+*)$*+(%
@r5775
AACGAAGTCCGTGAAGACGGAAACCTGTTTCTTGTTGTTCGCCNTCCTGTGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGT
+
6B5'$8:=?1-=A?2!9-&13<#HG+*1B?'4>@;FC?<)G-#%3@@=C/1-)0;>3)23DE3!#HH0-#=#95F87>@.59D/;E4,6)A5+5+.6G"A99$32
@r5776
ATCCTCCGGCTCCGAGACGGNGNTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACA
+
H5,E>!0BF60DD6H39=6:3'=2"5#!,E(C<2H93/<D".2$%*50#6706!=0*B;*+?!)H'0E+D%-*8-A/B#->4$*49;@$6,AD5.6%:A<73)3:?!61&5"/+=43;8/'6&=838<BC:"3;6+6-@'):9:,>(E%!6.G6:%5+1!8#H09?255F(@"&F0=E59
@r5777
TCTGTTTTCCTTAATTCNCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAA
+
F+E,)*CF&(&12//)0(>C;H?-F+""'16.)@<+**>83G:"H.*17>-$.&:0:.D(F!;32%'."-G%FC
@r5778
GAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCG
+
CA%E&+7<+."63'8;E<<1CH'A3*B+'26%04D=/.9;+5$F)'E45,H6;*GD%'(DH+;2!+
@r5779
TAACGGAAGTTCTTCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAA
+
G+A>7E0(F'1'D*FB1,644.;=-"$F!A0!"*.,@A#2,@=5'==!?//6&-FH=.CD!!.*1E;*G,@H)!?9D2'@#6)?9(B95
@r5780
TGCTGCCCNGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCA
+
)+$'#'$(%)#$%+&$$%#+*)$""&*'#)+#!*$##(!'$%$$+
@r5781
ATCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCNGCGCGGAC
+
"*B)A-G>B&:)<-.-CD3&.;16,'C)D&A!#B$#F5!,'97>
@r5782
ATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGT
+
G:00)34*#0!08-0+A*=E?!)5AEG9D$2<@A6&$'C/(4&H4";)&1""1#*56="2->:B)=,8A3/'0E-0$52FG):3DF!.@?9>7)*G63@&DE:;=@83!)1.
@r5783
NNGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTC
+
!.A(,G=%4)7D.C:7#B$<>1A7;-&H@/#@='01E/D?0/
@r5784
AGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGNTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCT
+
3-6,C:$".<$/4+)03,<?!=#7?#$*/(8%G>>.)7=A&D8G'5-7(</6>%5-+;F$/4;*/C,'CC-?+(6D&!##4&F&BGC//D-!!6E+,1AB33:,*=%/E
@r5785
CGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCNGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGG
+
%;*>!!?73C)!/+(H)G-F:@D1!3-*'1%)H)3#H%*E</+989F3$GG<.?F;1A?8F>G,!$8?,5(9,"#>
@r5786
TAGAGCCGNAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTNCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGC
+
E57/B8A%16"-!,'-D53?"DH<!18>8?+$H$?)F?>C/@@-<H0,/32F&4#+..+68F5,"@#5>41$&0;;::<H5)?:#'")7$#/+9!879B0?C(B!#2!+H1+H6H"HE5&E&./-0C)H,2/%.%%.0;HB7HG7/+</$F,D7D6*G'>-<E9+593*8;(F-?/+"0933)A7E:2@-4%?HF)B4D%,=3%A5C&.&*9;AD=%#52#=2;2/=6(!*A2"-4:&
@r5787
CNTAATNCNANCCNTTAACNATGNTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTA
+
)()&'%!'!*#*'"")"%(')"(("''+)###')(")##!%$$(()%&%'%')'(&#&!*$)&"!'"$!&)+%$"#!!##)&+'*'#"+)
@r5788
TGATNCNNAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACC
+
"%$)%(!+(!($!%"%$%$#)+)%+(+"*&!&%(!+((*&*'&+'#'%+*'(#+*()$!%&%%!!"&#+"+*%*'(*''&*"$++&$#!'()!"'&+%(+
@r5789
CGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCA
+
2<=&0&:A30-6<*8<B';B&/(02GC7A88F/"('G*14;?8@,<H#?!;<#>6E8E(4C)5?9E63.+%-#A,G&;?H;
@r5790
GNCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCCTTCCCGAACCCATCGACGNACTGTTTCAAGNCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCNAAGTCTCCGCAATTACACGCAAGAAAAAACCGCC
+
"+F"?+0;&'"2!"56B)C:'*@...3!$E8H=4-"6*<%+'4!@7%C:+B&#:FC%7723".$:@D@@&!+6:FE">FC=H87D"F:7!=;*BG;,?<*"&00*'?#+-=?*E3"*0)=.;?$D:#3$C@7A-84+9"A.5?/>993==B+4=2=5)<-C%=EG&8;@647)#@.A17@F/;!+.$.<38':/*9H7(7E$CE6,$071%(1&/
@r5791
GGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCNAGCGGGAAATACTGATGCGCAGCGCCGC
+
'F&$;<@(5'E(&,#"5EA4262@5,075C,+2D#%2<:((9>?6(%?.CF(&%'!>G28:#*;;!&7'+,//F5%0CH/)=(7+E>
@r5792
GNTGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCG
+
*#=%*;'"G!,;<6EGAA9>33)&&GG:5':9;2&)/$A1
@r5793
GAACAGAACCNGCNGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGC
+
;45?0'B??,&A6D9:5@:(;AA)B+5?128=E>81C307")'.;0A%6B81#<C8:GE:><5<06-49$G6
@r5794
TNCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCNGTTCAAGACGACGCAGCACCT
+
)#>*/;H5:6E85$B47/;!7>$A"6#).@+8C.!7!%6!-3<*&93=-882'%?)A*E0&!@/<$=@E=+&G=3+(+E?!*B7<
@r5795
AGTCCAATATAAAANTATTGTGTACCTTTTGCTGGGTNAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATG
+
C%97)!>C?17-*77C?G=)F9A3)31G7$<!F"41E89*.#7CG+0BCDF"7='132B5<<"E"2&E31D<#F5'B!%%?:DB%2$F/6;-#3@:?=BDF6=E&'6"+!*#8.4B$)<8;D'.!;D"*8"<1DC"?2"H'#"+3"".9%0)G9@"A0B975!!A;8,+>F8H*2/?"6#58#F0F34H$8$1B<"&5!?HH8.H/5E=$=(/%</4.E@G-*:2+!'CG5G9F&!F%&4$#7!9
@r5796
ACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGNGCATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTT
+
?2FH<&('"6*',4+)"%()590=83:1!-#"GBC<A+>BFBC8(1"988/34G#A."?F4-6FH9C8'E7C-5::(4:8##309%HHA%&@=?=-0&8;%<DG#<A,5B2B0=A#,.+F-<DD4D4G;14%#BC8&:0%)C@8
@r5797
AGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAA
+
/284-5-)!@G39(AC==F#G670-$+"2/A:*#9"D%E#7*(?#;"/7)4%#4D+FF8:?##1CD
@r5798
GGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTNGAATAGCCGACGCCTTTGCATCTTCCGCACTCT
+
#3>(+0*F6!BC."#7E73-6/>$>F&H4/86&DAB8*%C;&!+=:8:;?>@B?-9#&9;:D&3#%B2($A7&9G)#0>9')3H'#3+=BG
@r5799
ATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCNGGCGTGCCTTTGTCTCANGGGCAACCTGTGACGCCGACT
+
@<;CB-(.5.9F;?2*DC24D!'1%%$/,$,(CAB>:ED"+.:1H):D="8B7431H/9=*;&D@2&AA)0&F,-D/H!:-A7E70*$C3A"<AC'<>06+?;13A8G%%#/(H4H0=+$><:$4(H;F,>1F
@r5800
CAGCAGACTCAAAACAGGACGAAAAACCATATTTCATGCGTNCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGANCTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCNATACTAAGCTTTACAATNTACTAACTAAC
+
65?*;#B891=,.*D+)0!4A(#(1/H?D'%%$=5%'C3#>A%D55$:+H6:'00<;)+GC$BH?+,:/1$"CC>D'#.&?4C3//D:6!0F/?>3(G>A>3="A5F>9(&F!4+9";A8G;$=-5,$;59.2.('*B3@3$/")"6(BC7-@A'+(3>992(61449&
@r5801
GGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTC
+
4<'2/.$;9E/D!##<E03?H)7E.66&A=B#0!?.$96,C!8C?+D>C!G4)A956=;B$9-0><0#F#'(A+)21(?+A;AGG(?71.:%>3$%,
@r5802
CAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGNACCGCGACTACATTTCAGTNTGCGTGC
+
,>75?5*+=9A800%&F":E#?<<H<@&A0C"9:-2;D1,,!>&???135=*?#%<+F))4&)(4*?83"'=B%:67"%$89%=);5;62D<+(+@"4(9<1/29)@-"-@!34E3/5D1.3>86$D8<=<5F7C%@=$2@2':G->H8('8E;EF,3!H@E6#!
@r5803
CCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGNAAGACGGGCCTTTTCACGATCAT
+
!A;C92E63-./@$2:97?.8,4%1H9.&856%&.*6H73FA*(+G')-<D*35;7D1B0E3.=F(H</>
@r5804
CATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTNATT
+
1*=5G&!FG.1138:B?BA9@52C:4A?'4@))<%393CD92:?0'0A;<<E
@r5805
NGCATTNACTCNANNTNGGNCCTTCATATATGCATCCTTGTTTTCCAACTATATNATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACANAACCAATTGTATTTATTGAAAAA
+
%(#$'((#&%"!"##)#&'"(+'#"(!+$#)'*#'%%!(()#("+''!&#(!*&+"''%+)*(&'+*$!*'+(#&#$"!"(#$#*&*%'$(+$$"$%(#&$*"+!*&+#!%')*!&(&""%%&&'$+!(++"*&+$'$$($&+)**#)!&#*%
@r5806
AGCAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAG
+
82GAAE>$AD8:()?!:37""F!*<@08B7E,&.D1/41F4&08*'
@r5807
TCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAAACCAGCCGGTCAGCCTTTCCCGCTGCTCNTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGC
+
;5/C<72@<#35%);.;14FE:-$;A)/6E*<-,'GAG(7<42+DD+*D#''EE@H9>@D5/,?2ED/''@=*G!?7@*F).3!(G"F75('7!5D;D46BHC/@$+G'@C2A2)=8H??6%))E7F1B?+B#&45G,EF!')5"F-4A.%#.D(%?'3+@"4!!289;%E#':@1$BF<;-!$*>%7390:H20;28-0C@*7/G#0/
@r5808
CCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACNACTTTCCTGACAGTG
+
D&&80E07G8&!BEAH+:?0(:;1!G1.%FD@,2+8'026D3?)C3#CC5D11#,H=D;94/<.H.:84BC>A"=37H=5@70>!!@A"""1#!D-0""398163C5H%,'$G*H5DG$/F:FDG4C<0H6(8D=<-*'8>/-&=#H18)343%7)7%@</60>(>F4$?:"
@r5809
AAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCT
+
.24=4)/8)B53C(A;C##7%5#B680C9?+@)+73:%F#D#1:7$?1DG-5G:B:E:3%!?A!(
@r5810
AGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAA
+
G.=8C.2*F-$*+7%(/B-A(G5:3:7'+G!@;$>!*A%4<DF#1>//@=%%)B'9!FF;458$?)9%1),B$E-8
@r5811
CGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCNGAAAAAATCNTCGGGGACATTGTAAA
+
$7"9;.5/G9.&+6F-&4'8#F=*&+58.=G2<E)*83%A-223?-1$:D1<+5=80-C1F=-H!%>;4063.,?D9'#962/6=/>
@r5812
TCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAA
+
.E:"0@;730=@<)F8$=2(78H2<=DC%';;DB12>:!0E#"@>2=#&%'B/E54&'$3A4"G*'6":57;94,3+2E)DC;
@r5813
CCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAGAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAA
+
15%6.7?&693D''A3:#B-*$=:E+="BDG,4/1C8G@!'8%9D;A*,<;41)/:2*$):/2.(';D*B"$@-64:E@("@B<(,#&(+)-:,)=8)-F5:G,1'/0::EE8<8,%,F-
@r5814
GCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGNGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTGCCTTCAAAGCCG
+
?>AGCBGG=:5E:FE=1#1H)E')*)?,"3GFBHE,$A4E3D"4F=E=+')2)@62*$0CA#+F0>=.)("!AF5E&C(/7,FH:7<4'*5?.4$/'7'-77)1-.1A?5(9"".55"*04<2791-AF02+"="3?C=$C'.8=<7F411?
@r5815
TGCAAAATCTAATTNAATATATTGATATTTATATCATTTTACGTTTCTCGT
+
1&6%?8(B5+125E(@G1@E!44+#@*"5E($+31/?$F!G51A51HA4#G
@r5816
GCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCACAAATTATTAATCTG
+
9'%,&/)@=HD'>#:;/?=18+5.6(7<D#%G,8;<*5@=5DB&#*.079D/4-'2,B/?&F/';
@r5817
CCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTNCGCATCCGGATACAGGNCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATNCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAA
+
'E@!G8HH**,&0D8.D9G:6#7=2/F96"*1+43;-(F?8F.7?<9'256@B>8:%@#81&,80#,;CGE)0A"<D=07"<G06GEA0!%"&F%(3#=!";'&!D30HG%'%7"G#>!<G1!DFEC$*-3>CAG!6E!0,%('HC*/F:GH50$4465:7)+A(F;G;C5'(F4=7F)C2(E6=:7F4*E./59+<41*-
@r5818
GTCTTTGCCGCACTTNCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTACCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGANAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGGGGATACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGACTCACAGTCCGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACT
+
%5--F'4$0G.(0,C/)$31;+B/;,)&*$&'#(@'1-08>F2A7F("?=6/E%589'*(<6,7)0'H<>B)B:H/F#C45=,#C')1*>!B><!6?(2#*&);;#953%2E=*??@!'/./7=,#C</=G"H@')F2>;%*)G&4/0"/G@@%-.7<7"F;C#$G(B,.*7(7H:9;#9&(2HG6/CF*)3B!@A!#6?3.D.+EF:6.%-9"6-0#B9"H6#&2)C7#+H%/28E.+<5$D4=B'&/5#=,=3C,A0D'DF&C4'A#/!<>-':A:*DE-:;E3@&?>91@A/1A3-%D:6<5$4$?'@F9:-%0)%00G((3AED,A%(>6.4A<D1AH'2@*"+)9'?+?B*+*D@%6*2'&.1;?C489''7.4=+.D%;063D&6&G)*3-+=79*=2
@r5819
TCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTGCTT
+
3+B.:3/CD5D0&)DD2A<*!6<$*+D(!(?1)'8&5G>.>8/'@F,:$E>?*2&6!?7H"<28<#0;.=(:#3$4?G#+6$BE@A6*/'#+!@')#.5%7+
@r5820
GAACAGGAAGGCTCTCCGACGTTACTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCC
+
/3*'&<2=(B0)!#&&F&.-969/"6B5"1*A-"71B4#'<&?(*AH>4!AA+6<>3*G"%H6B5869?>518@HE,%D)G4A?2F.5=A/%F;==$7/-9=)E&H+'H?)D'F@*'9)-./,#+",=*
@r5821
CACGGGGCCAGCGCCAGCAGCGACGGAAAATCACGAATAGTCGGNTCAA
+
D.@6"%6%%A$D'28175:+-+=6E/%C&,'>4-$H:<2>#$8=B@-67
@r5822
NACTGCCCGACGGAAATCCCCGCTTTCTGTGCAACCAGCGCCTGTCGGCTCAGCGACTGT
+
!G.)@&C,1@G1D*#<7F/4>E4$>GA:B09=:9/D5(-8D(-5@73B>3C"G?-91,92
@r5823
GTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGTGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTG
+
%>2#'4"@:4G9G$4<E+:3@$<.7%,+'2=G*69'2!(@#G'CH6>,CEC1CG(E2'BD053F*(<DH'?3&>1H6AB3$,A.F<!!(H9A>*<C/"2CE1A>D8FB%@2;'E)*E:&%F8#5
@r5824
TTNTTNNNGTCGNACGAAAAGCTTCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTNGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGATACCATGCCATCACNGTATCGTGATGACAAAGGCAGGGAGTTGGACAAAATAGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATTAGCAATGCTTTNTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATNTTAAATTAGATTTTGCNTAAA
+
$'*&(!"!&"((")"(*++&"(#&"++)%#++%!!#%!!#&")+#%#(+&#()(%#'')!%%%&!!)"'+&)$&#$+'&'%!#('(%)+&$*!"!)+"+$"&+&"+(++*$%%($+$'(*++$!*($&)+()&)#"&"%$*$%)(%#'%#"'#++%***)#!$"+"$'+*'"()'("&#"$)&*&+)!!)#'+'&*)'#('&++$)$&()!'(%$#&$(*)*!)!'%!)'%**%*'"&%$%%%&!&#&!)!(%&(%'*)#$!+#*$"&&&&(+)+!+%*'"&!*!!*"#%+#$'($+()#$%&""("*%)")*%&$%!%'+(("($'+!%)&"%$*)+"(*$&!'%'"+&*("+(
@r5825
ACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAAGGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCC
+
<=99E2$B9<#>6"@)+A&.0%H;:9@%?'/<#G66@<FH/",1'0C%F%795$@)A@:8(A/"4@0<;C7;706E"G<199'H1E44$7
@r5826
AACTGATCACCACTCTTCGCCAGACGGCATTTAAGAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTTCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGCTAAGCAGA
+
+F@E!$4'&3E>&%/>$F:&=<(A;0<(@#G*$8/-4.*5B?9$F!)+/;GBD>/26;G#!<5?;#(5)H"3E7B=",65<$@'EF%H+2+@:*#A&%/.#4%>=-<;2A?9#AC7:(@:;28:-A#E;(0!4'5H$6E
@r5827
CACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCNTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGT
+
14#BH>D10':/B@<"1E==;)A35G<#;8!;7CG7"51A)B3'D86.F;;C?4=6*FDE'-@C7,3**=>:5C=%BB+G=(8.3!'#<()79'"!<D0(;@DF55!!%+99+#5<?-G:+0(8(8@':9;>'%$0''!6A:=89A8(<2=8D-775H7G+A!/,%;5#F
@r5828
CAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGNTGTTATTGA
+
<&?.@(DB5B4"1G;@G;@'A)BE.A=1<;$'F)-/&%D@F.'2<*@+
@r5829
NANAANACACNANNNCTTTNGNGATNGNNNGCANGNNCGNAGNNNGNATGNTCNNATNNACCGNAAGAANAGANGNN
+
!#!""""#"$!#!#"$$$#"$"$$$"$!"!$$"#$"!$#!$"$!$#"###!#"#"#"$!#$!#$##$"#"##$$"!"
@r5830
NTCNATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGGTCANCGTTCCTTAAAGA
+
$)'$C;2<8>!-<'5*'GF/!&6-7<':B2>6?8,83*7.#:*!=!9";4H03*5?5""7$(=8G&G70>FA?-<#9@&+B7!2:(;C0:9C%9@8C+*E9E2'E0>>$-1:(2?C&/6+/,A=H5;,>73;-1:.).G27+,!AG2'81/
@r5831
TCNGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTC
+
2>:"2&6<:8##2-)+$-.+>B2G5D<%,@B),"!3,H&=B?#BD3@
@r5832
CAGATAGTTGATNGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGACTGCAGCCATNCCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGT
+
GF4>+$,6+DE5/>99+5-=>5*"!*-(,5DE8/87#">>)26C>7)022-;:46"AH35B53A%@@?9G4GC>G2AF9.*+26E;?.!*/(4$'G>F?$=486H,0B'(H+1F3H1
@r5833
CACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGA
+
<!62;4,'*9>@F6G3&9@7D?-(+GC9:?-9H&$0D-,"%.BC!F/>7E@699
@r5834
AAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTAN
+
62GD"%B;,AG%:/#5&"3'@GG1H2DH3HD.D34';<$*<$?H2@=>&':6$$
@r5835
NCNNCGCNTCGCGCGGGGTATCCTTACTGCTTCCTTTANCCATTCCTCACGCTCCATAAANGACAAAACCGCCCGCAGGCGGTTT
+
*&!&(#)(+&!)*+%!+!!%$++!!#&"+'&)*%$++(')*"$"%+#!#$)"#%'+#+%""'(*#*#"'##$%#)$$&()'+)++
@r5836
NGNCNNGNAGGGNTNGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATNCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCANATATAA
+
""!!!"(%"!!%")"+)&**&))'%+)&)+'&%*"*%&#&+$*!((!+"#&'*#*+"*$$!%+%'&$$*!+#%#&"!%)&&#%%%")"$$*%++%!%#)+$(!&!!+)""%'&&(%(%+%'!&)%%$%'+%(!"(''&))&%#(!#!)')+(+!!%#+&+#&+'!$'++%(")%#+%*#!%
@r5837
CACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACTCTCTGATAAGCCATCAATCATCATTTGCTC
+
3"744:82GG8"%%)0.:0FBD?G1H*;?9"EA9841+6>;.51*1171DA/&4"0"(&7$+F(@&(
@r5838
GTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGT
+
)H<!#37-@(?-#/7!BE0F+.!/2"@0E5,*+$F;?;,:9H>2?=>*+.E9;:5<6'7D4&-<H4//"<0
@r5839
ATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCNCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTCTCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCACTCTGCCGATATGGACACGCNCGGCGGGATGGTGGCGGGG
+
FFAB$<6F:D3->27:3;E!HD1E:(H?-,G--<#-A<(7B(,-)#3E()+.)(#-'%/&*/CE$<.1"C##(..12!>$9+B!C!%#-H(:.?:<F/@$'EG"!99>@G;9%/:$DFB7B0$))F%&;2.7$4%#:!6@F$;8=*.(F!",#E44+6(H&!'&B!3(&;(F!(-1=%9E*!
@r5840
TNAAANANNGGNAAATCGGCNGNNTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGC
+
)$**)'("'&)$"%((*$&#%*&#%+!*#()+'")+#")%'")(!'$$)+%"($+')&%$+')""&("%"
@r5841
ACNAGGGCACAGTNTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCAC
+
*#$*(!()(('&%"++#!'%($'&&+(#)'#!'+(*$"*'($$&+++$*&!!(*
@r5842
TCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGG
+
>+A>=B&G,ABH?/F%1007A!($+0$+AG<%>;8,96<15F->9G*602!.<6)2!>BH0'!B(-6!,!(3-6
@r5843
GTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCG
+
H+?1AC-5+=+0-97>/*.E+F,7/?$E6F<6&4E!,@4H("94!&#4!5'AG49-D&18,%D40,"4)'=:<D:GB-6A&>16C:6FE9<5#*%!"(>$41,"C+.#)9!C)D1&E;7*)D$-+;B&?&E-&66.%)>B?6:4;
@r5844
CGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTC
+
.H';!6C4*A.&A@CB,EAD/12A!9C%3.%@B0<72E9&C1B?DA<%D1:)%2':F5:*G57==(>=G1BG?3))/A/E6D,6=GHFC3D#+)&FD$:2#"6$1@A&E&A"3F&5//1(B<A<*CBBG0?;753E"5#*74*>
@r5845
NCCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTAC
+
'C;2H.(7E%0:H4D'FC553E-A+1)(HFF?/-7G06#C=H(?$*E>H9,D>?@<F/H('>63G#/"/A'B<$/A<=>7
@r5846
NATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAAATTGGNTAA
+
*+&$()"#**&($!*&(()$&"$)#(+%(&")+&")##!+!#'#+$$%"''"#"&+*"")%'
@r5847
GGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGC
+
)7:8*E)&(?";<H10"2@00>4<@0%<'7C1(F<)"C&<8&A,B?#H222-*AG?@D6:/B"&,+CF4?"?.73%)+=9$9:"7,A5.C">";61=4
@r5848
CTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCANTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCNGACTAACTTTTTTATACCAATGTTTAACATACTTTCATT
+
GG&#5E(&'6G3.A+'D>>@#C2247?<'*H(!>A4+4#'/)1(E"E1!?9=4=.+;B)2*1$*)C$3A'B@C0%@)!#%A)+699AC)H/#CE6/**,>&GE78<.6%A$*6,HE83'G5#B4A&2
@r5849
TGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTGAGGGANCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGC
+
D=H$*A$H0G%.F,41&1G2E.3B:547@9)%AH0#>$&.7G!D%>(3E=4@7.;=BAE>';4+>4H%34HA90:$C"63:@;H<:$91#-""=,+H#3+4/<'?+0$9GA,:=&&?3<&571B%$*7!B'=G;<+/B9&<)0&0:,>>D%H#+)(C/!4"(H,HA2%*@ED)9H++-)4F0AFG-!:E@F6==1$</",:?A.F46*+$!*@D6A07="*HH%-617:$AD,/E!%2<%93"BA?A"++,9A2G><E#98=?6)18;FG9%5"4-/;?.BG6!'!)!!%'.2.F0)B.0/<@/;'@:>/!$'9'H-//7(1?B1'E.9>+).2FGGC9%HE!>"5H9:3<!F=2/@$H0-D5D/CA+G;3)".#B9A4.
@r5850
CGTCCTTAACACCTCATTACTTAGNGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAA
+
2E2.%$$F#3E)D?A4C#;6-0=7'3?H==BA'E+(.0B>%6&6D"(3"25@%25H4CD&-B>>;2(93E5&0/$<88C&>&2@8738D)!2?2+E3=E3H<C?327&B97-4CGF$.
@r5851
AACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTNCAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCNGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGCGTGAGCTGGATACGCAGTCAG
+
<3$3&H!/A7.D,(,F(69+0=%2E3*-+$D*+?5$&H8>-**"G"&(%B<8%60>H:C2#1#+C7"@&"$A!C681$(!=+4@./'A@+$0;0204F,A)-)2H=G$$:6C</09A,.F3&9*+G*C)A9A;28/7))A,B6H>D+/8'-3F++&C8:
@r5852
GTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTNGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACANTGNGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGNATCAACAGTGATAATTCCNTTACGTTACATTCATGGCTTG
+
.1-(506>H95$:7545,-'@%G87.1!0>;5(2+;7&HA60<,8C,=A!-4!8/?C<E#8F='1/=G.>-G@F:)*H0*+>A+"=F,+83+)7%.57?<6?;2!5F?470B0D#"D@.<99GGED50@)&6(')&B!9&-&>==:%1/=BC32FD@@=@B8C#7&7)%$G%D,'4;,(#"/.BD@1>'%)3=0#7"-DB(>"(C7!A)%@&&>6G-@?&"!==619C8HH'%F9,0&:"-57"@.,2%D3",5-:8(&'*;-.+;&(-5>&$7D$#&H'2/F06D-DHB
@r5853
CGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTAT
+
(;:>B)$@C(2H5<1%'),020"D15.8!0,?$EEB289G>0=B@*!<B:G9%!0?A2?H'5&D'
@r5854
NNAAGGAAAATAACATTTCAGGGAGTTGACTGANTTTTTTATCTATTAATGAA
+
"20&/!()(+#AA=#!G539)G6$(6&;.H/4-;*+4E*HBA).!%<'6AG#D
@r5855
CANCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTC
+
!(&0$(7E@->')4(#-$<"09+F0E5-&9!1&B>24&@,+'@/%G$*'B.&E8B;8:H<5&:&H!C#?+G)/
@r5856
TTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTA
+
?-HAF#0<&?>B97/,)9B>1??!&'>@7DE);B?+B!A3@>9@D
@r5857
TCATAGGTAAAGCGCCACGCTCCTTANTCTGCTGCAATGCCACAGCGNNCTGACTTTTCGGAG
+
<2+G3-B9+C57D.$,'2EB@8?><A7.H<F-273&/!(%B"14<,GEB':1/#;:0396-1*
@r5858
TATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCT
+
F0F$1-!9D$=C4?4&/$)3$0%B4>19E"E>+3F?A9*@);02+>/C0&@D"400=B0898<#B2,042:B&G"+67!H>(C;G!+;-@A+%5<G;CH=D=2B9<6:;4$,+(78''B24G,9/4:"=203B==?H%8?E#"%)7H&&/8D!/&@996/<*B<4>*-"5%!
@r5859
TCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCAAGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAANGA
+
>D:F"!#725C>8>F-@$><4@C<<4H148(?59E:!G(DH-6<#C4!H8,?;DH6:%C!)7?%H1!0D7!(A-!3#/14?5=F%<$2FHC+#><2-&=@,'57>#71<21!,C(#H@)F1?8,*61:7A-8/<;2G,92$)H3F#D.8E?'/?=/.+500"E&C'*0'%BF$$/+-"51+4,==C0,,1*A&@A-;4//&@3C(*@"1!:/3456>*"AA3)04+1:555(-?)<";E>&5/$<"A+E8$6A2G*;*('*)'C7F.0*8./B$681/E0/"HG!#2:G*!)G6HDB5.1=-4(4(9821E!06'@@:6EF/BFG'?2-FE@.18>9GD$BE?5=G41(549
@r5860
ATANGNNTCAGCGGTCAGTTCGCCNGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTG
+
*('"*!"&*#$("'%+(("&!+&'+!+&"'+#+*$)+)!*#$+%%!"+!##)"+(%"!&(&')+#'*%#&#
@r5861
CACGGCAGACGAAGGGGACGGTGGTCAGNTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCG
+
@*/(/:!A4.,G*##'+20;:5<1><3;??95E;(+*+-'/:A#9!$F#+2G!G*%D!/*@#>?+B=8!:9*4/>;%0,8AA,4E51!/@ED<6&2C-9@A3!
@r5862
AATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAACACAACTTCAGACAATACAA
+
&AC+6FD>!<HC%$2(B360/>6'1F6+-.)!E+3$42;/:-A)?$8==2>&8D'&/8(6%-1">0AB&4DAD@
@r5863
CGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTNATGGCATCGATCACACTCAGCAACTGCGTGNACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTT
+
9>@#*+',66'0G)E62;$#@55'FCF.3%<=,F>33"@6A75--G;6@3%?D0=3B,87=="G$6@7H>==@'(G!)21D">*<C#H2$G7=3&F2;*(*H&@>>1G.6$8(1;3<#=
@r5864
ACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATC
+
B.>3!+!F'8,&2$>:0?1,>)B0)7A48,790G>;:+EH
@r5865
AAAANGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGNTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGA
+
<4*(E#3H;%+4==B*'.4>F;"=9G%F+)>A+;874#$037&;:=&3(0!:.%50&D;6:-EH$$D7*::H4="'*F)C6.:,3D7&D6.2:='9*F216#5E1+2%4#6:,@EA#+!53*H""4A6(,DE2&H;6H:2#!E<'"A56C;D5,(7(8F71GG19405:F*C1<@0CB"$
@r5866
TTGGTACTCTGCCTTGATCGCCTTGCATTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATT
+
-?@4!E36#)FB8B3'HF@9/;C4!D:G832'"3(GH,:/$E#:H-!<C);2&0D&A:B"(CE$718$'4/69/?7&E"<>>0B@69B"@>"!5*-C%.4:H;7"!>B&?!G.!!//CE"&1"2)A898>.6"2(-?%A1)FEE=/='F20=0BE!0?1)=?DH5$?#<F#3+?0!-=140#%
@r5867
TNTGNTNGCCTTATCNCTGATTTTGNTGCGNTNGTGNCANCGACATGGTTTGTGGTTATATGGCCTTCAGCTATTGCNTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATG
+
%""('**$))(%'#"$$$"'!$$(#')$*'%'"&'))'&*+(*$!!)*'$#"*$'%$$'#'$'!*("'!*!%!*"+#$&!+$$"'!+%"(+*"&"*'$+##$!(%'!+++!#)$''$'$$#!'#(')$#!'$""+%&%$#**'"
@r5868
TCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCNACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTG
+
8@A?*G.@<5$4:6>"EB3-?F1E+90@@@8(.G+%-94A%3$H?/$-/?12=%0#6-*:,9F76%321A9*<*=%4/)CB@'B,2-$9*C%8<:@!/2@!?%648>>-+D@"F+'2-?<?$1%!B!=349;68*'BA=E%=DB?(>$(BHA7C?$'E<6:>4:>9605(4C=!A2H9-5,.*:#
@r5869
NACCAAGCGACAGTTTAAAGTGCTGCTTGCCANTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCA
+
"/$&;09>4E0*.?6E:@<47D<8(9$H$,*+@#H.*,:F.;G+E!%?774,A)3=A(!&D>054<F08>4B%HCDD#!FF>86)5>C"(B2H*>?5%::*6!>;D?%#32&-.D9*(0"B4*%!8/<).?+;C
@r5870
AGACGTANCCAGAATCACGGTATCCGGCTGCGCTGATCCCAC
+
+)!#*"%+$%$**))#')("(!(#"$('"'&)$!)%#!+)'!
@r5871
AAAATGGTCGTCGCNGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGA
+
>B30%H;GE;<9.H*!(,;6/(@4>%<G&+A/EBB#;1H!13&G3/*9-'*-,5"B,B=!6=0BDF2"(+')D!6"4=E;B6D$5.B8'
@r5872
AANGCTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGANCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGC
+
$"$&!*)*+"&+('**)%%%*')%%)!!)+)"*)"+#*$%++(("+"&"**%+''&""'(##")%''%+&+*))!##'#%&"+"!"&')"*&#%*#*$'))"&"*$!$"$'$%%**!&"&#''&+')
@r5873
GAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGNAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCNGGTTGGCTCCAATTATTTGTATANTCATAAANTCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCC
+
*F&2G>-*53,1E-D>?/.'E(&"D*?@EG*?7C(3DB)B9%!+F8<9+F1A.:*?+081#-@9'FB!/4,@@3;:)FC"%B@A*>5*;!5?A7!%4D,+9@---*FG&;<ECC+D>;&9+!'??&.A&(!&%/9F)4.1#;)$@G5B.A/H52A5'0?&'H3+25;D3#7=DAH)@-'-)$?F$/<'D/8=<06H&;@#A+A75FE.:1B=26.F'E7374-:"6*B5/&3"%>G<67&&(>A>05))0B>)"56%71!.$82?<G39F2AC?,:&G&EA1$>H7?9.H6-@%G)H"6,#1>>7<4',+!;C'"C;,.AFH2#E**!?&?
@r5874
CCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGNCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAG
+
"5#BF*/:/*?5D7'/>!73?0FD%06EH#(;=;3!>.=&;66/A1=2&,H%9H*7%8$619#57E>:?</*HF=/?#D0@&>50(D!5,<$'1H.E/6>$14.4*9)
@r5875
CAGAATGCCAGCAGGACCGCNCTTTGTTACGCAACCAATAC
+
08H@1$)!*:D(-/:<;(6/F4:3A,%1)(#'"A&:G1++-
@r5876
CNNCGCATAAACGNANTAGNNGAGTGCCTCATTGCGNCGCTTTTTGCTGTCCCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGNCCTNCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGGTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTC
+
"%!*('('#'%$(((%%$%!"+&)'#!!%*!$(+"*&%&!%!$'*'(+*"()#+)%'&&$'&")#+'#!+$++!*)%"'$)&&$!'%**+("&*&&+$"*&+#")&))'&(!$$)*"*"+(("+"*!!"#!($*(&%%("'(('$+*'$!+#%*!+#++"!!+%*%**)%)''!&!&#'!#&)'(+)""+($#
@r5877
CGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCAC
+
F.001;H.:>8D@'(1+5%6G7"$63)$4E;G-9)041H*8
@r5878
TGTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACNCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTA
+
60$'<$-?B0A>)93284@C%29:H"F&)##%GG=B-6+F<@2!A2')3%+);547))A!A:A$E%F6,@HD<.@A(G3193<'AFE?/E-90A3B%/"805A,-E?0::#&0@")#H51>:BBB=&G:"
@r5879
AAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTT
+
3'5G))GC?19B@H0G,?1>DF/67+?@59>H/DB67"/"G$&*F7;+H3E.H1>
@r5880
GTATTAAAGGTCTTAGGGGCAACAGATATTGNAGGGGAGCTTTTTGACTCATTGNATATAGTCATTANGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATNTTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAAT
+
*B&'<#C?4>.C-3#7;?2;;:(@"1F9B2=.("E8HE(>F+'%639F/;?GA75B=./$.0>&38.H+7H3#2-7D4.3'H,23&*3;<FG#9#?:8:9F?6"A3H4'=$GGF#G,=),(8!:%9+D$F..-'?#"1=1=F45,EF3&+':!%:1:@C++C=*=(679CB'A6+')?<CF1@6F&BE5;A+1,/>+8HG.+E*C?CE)F6G1G3!$<FB(@1!49%<@C-"HGF9A:F>
@r5881
TCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCAC
+
4)/'>H#"$4E9$4B91'D$D2+.H(C0?>%F3:-A'EDD,2C
@r5882
AGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTGTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATA
+
->?)%"726&%(1E.<9.H?*+!<%GA=+$5!,6;F$2'53&,D-<?>3&%+:5;-2*%>74$*"%H>";2A,%=DH236B9E);&7A<,'7A9$@*?*
@r5883
GCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTNGCCGCAGCACTCGGG
+
@./.:@DB5+F1DG'5$3&$;'H7E?7&,B3<'#/C3DB5-1:G-G:=?,-/-(C!3,948+6=&&:$2":0
@r5884
CTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACG
+
G7$C,1./,=$8:/@(<."4"G:5=5.6/,-<8>*32@D=-<%F,7F8?*?39:7=0B8%@4-:)=&"
@r5885
CTCTCTGCCTGCGATGGTTGGACTTCCAGACGATACGTCGAAGTGACCAACTAGCCGNAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTNAAA
+
++%!(!($#"+&"&"*)%(''+''(%'%!#(!%(%)*'%&%""$%##"'%$)&'!+'%"($+%+##)"+&$!%%+#'(&()%*'+("")&$#(%()$(#""'*#&%!('&($+'%)#&'&%'$&+%&&$
@r5886
TCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCT
+
'C5$'7G>C#A;8E((7'**$++H2.(<2&.#HG%H&>:"C/4-
@r5887
CCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGNGCGTAGGCTTCGATATCGTCGGGCGGGTCATACGTGGACTTG
+
';288B%,(-8EFFH?ED;7B64,@B%FA42A6;)A9=4-C:G?*5'/-'$5-<3**:/A,7EC'7CDC?H"!!1GE2@2$'""4&EH459.A?G97HB25F?,&##4:C+*H5)332,A>>#D+
@r5888
TGCACTTTTCCGGGCTGACGTACACCGTGCTCAGNCTGTTTTTCAGCGATCCGNATNTGCATCCGCTGGATTTCAGT
+
D8'2."0-8@<F13G=/:%G=7+78*-B0*@B,/8>5/:9;.(7@<H@8?'E.=A2/%E(->43F+C.B,:0;,A.@
@r5889
GAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTANGACAACCACGGAATGCATTTTTCTGGCAGCGGG
+
)E-"B7!F:9&:<9"B/AC>H@8H+%;ED?-6'2H=0G:<="B8E0=38%:<)<"C70.@)6>)#FF/0075*=+#4=#
@r5890
CNCACNTCNNTNTNTAANAACTNGGNNNNATNNNCTNNNNATNCNNGNTAT
+
$""$$!!"""!"#!#"#!"$##"#!#!"!#$"!!""!!#"$#"$#"##"##
@r5891
ACTCTGCGGCTGCGGCACTTTTTTCCGCNTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAACGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAA
+
'@0DB2+CD#/?FF7;3+0G7*#+.%&='68"A%<5582&7="/H?F)-CF);70%/>32=/<&#H#<C-2(<?.('-<<9$.A*&D<(A&B-.G'+;//H,0,"B1)!B9*>?.<$E53EH#.#F"1C6BA$(#:AFEH,/&1*FG,%!(==D,*+2>,D5<*9,3:-;'=+/@.?HCB6345=7.E/59GHAF+';E02=0>32:&B07'*H9,%:H4#F!!2H8FC4>9"!=2'&.G?#!+:$:A((H+'@4@:4%E3+<D12(3=?E514=C</,&E7+@3CE.A9'E?!?*/@952.-E)(6,3B"
@r5892
CGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAANGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGANGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGAT
+
B.347BHF0D<C##:/6H:/4@$=$6<F505+*2EB5$(D-4?E54-=:%F92-6@+A-#-#(-0:=74,E'&"1</9G/9'/1<//-?3@74@:-1#89;#/)-A,1(;"7<.G:)(EH3$@1G5)&/B8!("-D/&4+A2%A*CF2,,H%03.+$H!@69.=CB1"<'"0.@.B3@67H4227D@1&5F9>&D6F
@r5893
GTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAA
+
67E1&,8&7#;;"H1*9!$/'5:=EAC>H+9?@E3#<HE7C"=8;904*==H!%*6EA4#&7D.#:?#@+>70<5?139"-71'&1(-9(/+6#;/:E+":("1.+,>68(8B:;2(&E+&3E%E54=F=
@r5894
CGANTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCG
+
(%%#+('!"""((!()*&$)'+%!+(#%&%&(+$&)+'&+*&#&!
@r5895
TCAGGTCTTCTGCTGTCCCCCACTTGCTGCCNCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAA
+
5&*3"$>>?F'.'%F%=G/GH++(1EB/$'5BH1CD.+!>5-5)G9E,(197DA#"-.,,D!"&'7#3*5*>3<&<G,@)/H/$!-42DE!371?,3E>/'>1DC1-:6BF:+<8<EA7%49?<5@>)107D8DEB**1&+,D!';%F1/F4("$-9/"CA>.'G'/=+(?=0<DG43<H9$=$
@r5896
CAGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCCTGTCATCA
+
'*+*)#"&+!*%%+)&&&&(%#$+%''()!+)&$++$$!*#!)!!++&'+%))((!$&#+$*+%!!#(#*+$)"!!#%'&"*$!()+''"%+")"'$&&%#("!"!!*$+!(##$
@r5897
GCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATAACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGC
+
?,;1A,FH#<!F0&B<'=-1&"@*69F:4#E!5$A3H!$,1=*8B&72)HHF6DB9,3!&@+F9G5?$,!,&?542";)"$,9H(@B2H?$/6;0@!5$E<F<7-C;7(F57&9
@r5898
TTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCNAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGNGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCC
+
$<1@>=)&AC55,.)D@434206G>5"B'!336F/82.$#+2/>/<;'H;/%GD66EFGE%6='87B?;$B<00'$@?/C--@E&<'F#-!B!F".-E?-0!#$=>G.1)&2#/;1;;.A??0E-<9*3":AB.F#C45D1"$&+!B$E4<&10<1<71%3FF5@C
@r5899
TACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAA
+
HE0:!=D@:(*''/&)?E+!@EH9(+11+;H<@353A46<?.4,?#E?%E+F6555."$888GB1:)6%5
@r5900
AAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAANACCGATCTCACNCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGNCACCGGTGCAGTGCTTGATAACAGGAGTCTCCCAGGATGGCGAACNACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTNCTTTCCAGTTTAGCAATACGCTTACTCCCATCCNAGATAACACCTTCGTAATACTCACGCTGCTCGTNGAGTTTTGATTTTGCTGTTTCA
+
*6H!!B?4,0H1)1?#?:,+/5B&C1=E?4CE@(H5A@G,E;&BACF85E#5-'.*B@4B92,8%=!6'DBG/,F0-';:C*/<>!56%H*24,71+?:#%*CH<H:F08F29?8;!8%+H":F,>;.'%A6'"6DEE7"B<(1+#14>34*%4:#2B@.BD.@"6<7%5-9-C:;+9H(?7(2#$(F>G/2"@!66*:=D9/4#AE=:EA=#EFB79&,0((#B<2/"AB<&?C-6)$7,<@,D.(#,;C#$&:3<,/G",:00DB"%-G54DG:<=D&,9(07H'*ADF##C.A+/3-5HBC/B.@6%)*)3,@GE2'3:.="&-12&GG0362+!3A#8$4CD2@A!)GE1+H@F5&&7-1<;A*+"&D&=F@<-%@C3<//8G+G3'1<FA:!&!<<.:3?F*::GB/-!2**)&?,$:9?!06H6-!1!1D#8!CBH,A!H!D<$#BH35=<*6#5FH15
@r5901
ATGCAGGTAGCCAGTGAGCATATTGAGCCGCTTCAGGATGGTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCG
+
B/+<@17*85G)%!()C/-DE=:($<C3?0E0360-&;<C%G)>#E?;F1;H5H2?F+C9#D=,<6D9-982'#64D#
@r5902
CTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGT
+
&3.6,D5)(:E=>F4#BGC,5'%8,E5BH+E$E%'"8(4AG6'$D%8A#+(&@!>=A7%(?/>'9'&C;4E+','6?&*G@803=3)1B01B>G<(&B
@r5903
GAAGCGCGTGTGTATTGCTCACAANAATTGCATGAGTTGC
+
)BG(98'H5#/GE(@(%C8@.E<1)<AGC#F2##H#32E<
@r5904
ATGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATNGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTANCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTAT
+
)$F>'<72;)3!CH269=82A)A6:.6>A*%5-6C+82C+7=@<(<50A&H!,E67,1F$4,17/"C$)D0<.8:FD*5C#BD@'F,7<%%6/E23@#A@2(-)6G:AE>'1.%'*22+*<&H69B>8##;?52-#2GC!#)E&09>"D?H6$$%%-%0>!"?)85"!B'CE2-D5#$HA!9<!*8)?,!!
@r5905
TTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCNGAAAAGAAAGGANACGACAGGTGCTGAAAGCGAGGCTTTTTG
+
=%,7(C3&@%FF&G04/:,>;";!B0>78!1A%:A"999-=CDB+970@*E%#4?7"%*+G8#+1G!H$/.G23?HC0#*6G5
@r5906
CGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGC
+
A%+-/!;-)59'0;;?,9"<";$8'1)!B70?4<*D35>".GGG5$"=090A=DDH"3F8!
@r5907
TGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTG
+
D9<8(+"3.!""."F0"B9E?A$&.0H4)73<:,'8.%?A:,6<B;0G73-GA65(,+AA2$E/*"G=H7
@r5908
CTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACCGTGACAGTACGGGTACCTGACGGCCAGTCC
+
H&:C./DCD/?2-*"E/*+-4("@8C@G'*G:!<+)#BG/C=@)</=9,%$"$/84*C5)4EC)4H-%4>888=F6*'A4,5ECA*B-B$,30
@r5909
NCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGNT
+
$2D5H+:60@;&"6-90=A>5>A%@=<;:?5#($1>0%8D247H3".F8:3G,"H+;$&4E*"F9B"E:?!/1H,@2='
@r5910
CCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATG
+
-&E!"!A!F2)C1AB3.;%&&+$B2.87=C?*)--!$5F>C
@r5911
TACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGNGTGGACAGTACAAAGG
+
/!A7@)@=*#/#:D=)<$GD:7$B"*$.G+0+G+95C;'?1E>,<&6=.+9HF;
@r5912
CCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGC
+
$C*C,,>C'"AC'=4'CFD+B0;G4!8))1E=$?.;+4D)<2<+2<..:",B-G0B0;F64@BA8E"<!7/41F/(1;7E<>
@r5913
CCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCNGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGGCNACTATGACCCGCGTATNAAGCNTGAAGGCCTGCAT
+
:5?+314.)$-$GF=<;0B/<GC0#,&7>6*G6H:#%>(5;;??)8?'7A101:/$G'5"))"2;7CC*%'&89B($40E;"5)E/&001+?<)&-&)4*G84?H%5A98,A?9>"H9E"2-//#-#H)G-69+%$H-.0E29+@3#C!A#+
@r5914
TTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTC
+
>&=6FCGH8E78HA(C*5!3)B'<5)H4!->?%:C5A/+/#>=8.!1:<+FH8/E'!=/0)-5$+,'=)G4'@9*;B.1!ABH03'4E-?<0=!
@r5915
TTGCACATTATCCTGAATTTTCGGTGATGCCCATNAATTTAGTTCCATCGTGCCGCGACTGCA
+
5%H?,E2!.FH3-!@!(%3/0H>D=3HC>>0G,<HC>&&$FGD0<8+03$52A/H!9'6':25
@r5916
GGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCANGGGATCCCATGTGCGTGACG
+
,B@AF:3F@(/803#$-?/(A"&D5=*>9>@23G5?"D,*22;C732<EE$'@-4!
@r5917
GTGGGANGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGNTTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTG
+
0H%62E=9*+G<7;$D3,*B(51)/C(?153%:9H@'-;A(H;":-798.!#DHA2:874%FH8"77+;';:ED*!HB1:;+D?=5?6-%,9G'GDD5?2B"D2&G;"1#=>2>*472-C9:E/8:*2:)C@?05A:A$$<:/(:<(?'5()&
@r5918
CGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAG
+
#D/G*H*?A?+0?")*<9H1/9C>/*A+$'7GB*<*1)%,9!9&+/BA4FB&E$%%$B
@r5919
GAATATCCCTGCCAACCTGANTNAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGAGTCTTGACCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAATCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGAGTATTC
+
84>>/GG*$F<FG?'<54C7-&A;*D(</EBD0BC:E132<0=<E&$'E79.-/34HE;6=$/0.?/$;-;/E/8E>/"3)=%1:8$*:08H4H2A=#C0+A##*>)?184+FFBG7/3<,C*;*;60=*CF@2-"$=5/6/7$H*29$760:8<AD:6(23#<5*44/<0::HD',;-"-)/C2%-H&G,3&;,4:BEFE'5=A'%H8(1HE;
@r5920
ATCACAACGTGCGTGGAGGCNATCAAACCACGTCAAATAATC
+
+1,4F#D9/-&GF@EC6C52/5<'C7/2)%8F2'1,1G,,<3
@r5921
CGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGC
+
G:6;%$1+7,!B>G4H8&>/%G8+8&>9#D*>;?<#F/71$#/"5)/5!8.6G%6!($,B.A11<D$'B6*D1@&=C<4=H-
@r5922
GCGACATCAATCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAAC
+
/&+FH!6725$D>,%.;G,!-H41'@2$;;:>*'12DF8D+)()G?0;<<CH289,GFB.+:)C8#H<,?
@r5923
TCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAA
+
@(8)FB;H'(5:?/=#G28%D?CH:)/2?39.D3',7HB.%=67+
@r5924
CTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGNGCCTCGTTCATTCACGT
+
>)9*=/*B/-C6;/E>9.AG%E);G$A>H/%4%0'==C3.H93+6!<(%>",F#G,H33CB&39()">C%-=A*/-*;!9E(H$+;A<*$$"@=B'(*3)A1A+
@r5925
CGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCG
+
4)#'*:60?<"4)FC.2;ACA-B4$01')GH)C7<B%1,E>2A8$#6-=F*@8,E')4B8<#F)!H,4<5:04!6#H@0:'!*&3;EA-@'.+;$?G*5$1B:;/8"%(*297*4":1H,1C:"70-80#4:B6BG@
@r5926
GTGTTTCCCAGCTCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAAC
+
DE>BFFEG?CE>$@5;)C0339!/C?3#6=DC/?A55)H&E6H:E55'305F+96A;CF8;F7="D4>B50!38!)F"*!1?"E/'92C()2H85
@r5927
TGTTACGCAACCAATNCTATTAAGTGAAAGCATTCCTAATATTTGACATAAA
+
+#9!-'%<+0,8>(3*>5;84-@,(DABG@;5>#+3?-=,*4B#<F")&/>*
@r5928
CCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGC
+
"BFF%>%.(6?A0:35*'+9-<$5'**A&B!:!'A1G3?.H,&1%>C1E@A5H1F,D$5<D(10#D*1+3F/BF1
@r5929
TCATAANCGGCATACNCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGG
+
%!%)####++#'((+)(!&(*)""$'*!!*&'%"!#*)'))&%%!)(+*$%!)'*"&!$%"**'&%
@r5930
CCCATCACCAGCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTAC
+
HF'!=5DAF8C3AG)H4,F;A?;9H+9+C97*8$C=?4"5->82<46''B/)+4/*9$=A92$1DAC-C6>317&!-G?*!%
@r5931
TCATCGNCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAG
+
+,('62$&*FFG6A2FDG"6&!E+.6G59';-D:=,F'*=F':1'>!'/><@C/E+>CG6"A,,@0?0=H/'@AH463>148%="'?D9E08$)DC/./*1E0BH6C..<*5DF'!
@r5932
NNCGATGCCGTTNATGACCNGATAACTCCGGGCCTGTCGT
+
(#+"*(+"$%!")%#!&"("*#"%)%"%"%"#%&(')''!
@r5933
TAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTT
+
E/+G-8*"(B'1064,=!-%13!<.0/.0);&!-G3#",D:',?@-,&?0<*2-E
@r5934
NTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTAC
+
$:',>8$,@+101H"E6#3!)H!#F0>@C*>A0!?+$>46HB:)/52?C@A13F0<*;0G"G95EH7@3";3
@r5935
CTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGCCGCTGGAGAAGCATGCCGGAGCAAATGAGAAA
+
220H"@7>$%0G:$%8)!E!G.,7F,5$@#'79/0:G78@7=!+/DE@"54)9,$AA;7/(2#0(-A%%@%
@r5936
CCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAGAGGTGATGCCAGCGATGCGCAGTTCATCGCATNACTGATCGTT
+
(.C8A'B;604A%!7/03@3D%+'9?/,%:A::B:;H:!B6DG$-7,":3FF%A(;%<@6-./5);"?5!+)$F/>02##F(%8F
@r5937
ATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCT
+
/4*$0/D<&+2=4)%4=H"=B9905/<F&0/*#?F88(1:GF2:H.;4"HE2)15"%2G=#9@*1$7/9-*2'5.&&@
@r5938
AACACCATATGCATTTAAGTCGCTTGNAATTGCTATAAGCAGAGCATGTTGCGCC
+
4*A8/;48'4GC1"-*!69-'?%3&-"+<$@,D1B$8AD)C#57-*!6+0+AA@,
@r5939
CACGCGGCGAACGATGGCCTCTTCCANCCAGCACAGAAACATCTGGCTCGCCTGACGGGNTGCGACGAATTTTCGCCGCCCTATAAAGTACGCCCACGACTCGTTCGCACNGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACG
+
?>,A.522/CA-D8D$3:22;H&?,9!0))=B-*H96@,/?)C/"AF4B4&'5.6E%89.E9,)9BCB"A%2:A&/-5+;C%C$9HDE851+'F6,265=3@9%3-2G+'H83220$HH:4)!'<'81F20<2-7>E<<+7(0'6,29F@,!:F>B.E>GACFG5%;
@r5940
GTGACAAGTTTGCGAGGGTGATCGGAGTAATCAATAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTTCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTATCATCTTCTACTCCGGCTTTTTT
+
6!::6,(>4>=,H#6%:$HAD$>0**&0".B!<1,A8G*#%F%!4C,/''23F:#1@*@0*<.2:EG*1++AE+;=5!7#D8C3/#)5<#,?"$>>$C0;G:-8?-,+3HC##$5D!FGA>$';6G-<!>:243:"%0<.'0@AB*:9=A-)2A&;.,,'617<8=)$65F$;H%4,#61
@r5941
TGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACNTACTGT
+
F:?/;H.1=755:A7/".$(13-'*!E&CD7/=;6>D@F7>9GD6"AE-0C%3';H&+61B7#;&(!$#
@r5942
CGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAG
+
#>?CF<2'1E0<$CH,+&%;C'<H+/4(6&D%.@%E%7>:C#H'6
@r5943
TCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCT
+
5H#35'!.EF++,;,'FF83G-CG95>5*BB%><F'>2HD7.<(?94D1G.#9EC2E
@r5944
TTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGCCATTCATGCAGGCC
+
=>HE7'@$'--D0A,H41%3@'.1:9'2:)47(%F;))1!GA5(A$+5;8F.A03F!-HBF$=.-<1D'C>EE?")3$':6'8
@r5945
GGATGTNTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCACTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGC
+
3,H71*/$7)G=64@6.G>H%<9<*<.5)&$G+;E9"<9':28%;#DH7#ACFEA+%??!E%=9?,@;,;/*3#$;2<F*(#GH#1*7D:<@5='-3G!3#=6/FFE->!9%"A7)!/4G8GF%C>C<)?&BH>$@7%<'%%>GG5??B,5A(4,'.GC=1!8/%6*'03C"CE*;:)2-)B>8G#GH=9%$#"F#E>?;A6-4=H?-!0.C1$2+F#2%:5H3"'B1FE4@922:-E/*/$70
@r5946
NGGGGNTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCT
+
"'*"&"$(+*%*#)$$%&*)+*(+$(%%")'&%)&%!+$%"*$!$%#
@r5947
AACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAAAGACAAAACCGCCCGCAGGCGGTTTC
+
!+'%!)++"$#)!+$)%!'$*%#"*#*$**##+*#'*%&*%#+#%!$#")$)*')#!(('''+*%(!)$)(+('#))+$+'*)&+%$"%#$*&+&!*#'&)'*)"#&!!+')#)$'*++$*&)#$*&&)&!("%)$&#+%%#""$&+*"!'#
@r5948
TCACTCTGCACCTGCAGCNGCCGGTCGGCCTCACTCAGCCAGGGCAGAC
+
"*E<9421;*((!5G9=/+A),5=$.9E-./+#2E#7!5?8/"#3.?C6
@r5949
ATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTNCCCGTGGCGGCTCCGCCTCT
+
%649/?,#-<+2"01F1;*(C!(7CAC+&&-=4!%4">,@C2.B/%4!-3=435@,3%F@,D'8>D117=.1/9':596E/7BH/2$;$-G""?@*/+59<6E%8E6+@=#<0@4G%-,,-(=G#9@7%<-<);#0D-##3;F*<!&8+?::'#&H8%/HBEC44H
@r5950
CAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGG
+
>*41D!7%)/'3.?G3!;2&$?94<42)A<8<#G;:1DH1(F<10A?@$,/E%4=4?C!@?B9D;;!C?D&4?1"*;:G/)B%4H8/H>/E-:3+50<D5E$6,AG33<64/E+50(D$=@7(00H;(+4-5>5*.E8*.A.'G'(;3+B!HGACF>!.9=).@?)-3,$A(H*F9B/"//9A77+14BG4$-CC#E!>>?4@:>H84)(+);.<A
@r5951
NTGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTNTGCTCAACTTTNACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTT
+
!*$+""!!(%$*#$#&##+$$#(%%'+'($%)&%#"!'(+&+"*"(!++%")!")#$+&#%"$$%#!#*+!)$!%))"!&*!*((%++!&"#('($')#)#!%&#)#'($''')&*&%)!!&(#%#$)*'$
@r5952
ATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATNCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAANTACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCG
+
-,'8-F?5AC18=<<"9&C,<45?07H,0?&F)&%BBE1GC)=A,<,=*ECB.-.E2;)1GDFF0.%0C<87+)=6!916D(88&2B#A%G9"A<>4?.;$=">B'=;;3?+G0E2,>##(?*AB3?"(6<->6$.%E-F/"$(DE.">!G@C(/9G#A93>>:("+>3-:;"A,A;!><AH9,'"(/='9'H4(>$().$134-%$DF!F#9C(7?F7:F-,C5@FF:=F>8794!8$9G&&/:*56BH5%D(?G(G9%-+:6(E3'CH/!-6!B/8+3+97B/6-2F=>'A0975*?CD.77-7?4#G>62H>F"-75G@2.4":D'A2&"/6(,C?!72&&0#=;$<3)&1<@D$F3A=@5:%)%:0/-,;BG
@r5953
TGCCCGCGCAGTCNTGTCTGCCCAGNTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCTGCCTGCACTGCNCCGGCTTCATCG
+
50>@E@1<!/@%>GD%C7/(5;=#G-&FC@!*-(;63/:2E(D/.39C8D$(6DH7($?;5CAGA&.."-C,G<80"%58.$7GGA->0&!#1/E#!651,E23$B/$0D51;C$?#F="0$?#
@r5954
CAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCNCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTNGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATT
+
6,;1@G5%+*&32:'%2HD4"4$$(6*59'%B<.!"#?,)'#E=;)9C-A9G#;-8#%)B#,9)H*)&0F?3"?5>).9!-3@(!1>-H-#%&"3/C!49E2""<&21@B$>;D;?3-)@1#$#B/C)B(,<;48685=?","0$,,/8::4D177>G2;==>&4C),7-?HHG.((E2%1*!)0BF,&",!&:?&'-.%'/)D.,"9>;4F-C*29C-+H8'1>G)D##5%7C?
@r5955
NANATGCTNCNCGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAANAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTTCCANACGCTGTATTCAG
+
(&$&%%#)$)&+!$%")*&#&&')!!#('*$!($#('&%**+)&$!#&''$%!")%#$+")'"''&'%))&!'+"$%&$!%$+$&&$+$($!%&)''&!#"!'+&)%#*'*)+!+*
@r5956
CCAGCCACCGCCATTAAGCAGCCAGNGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTC
+
=8B"8$$BD.,FC0+$E-7'28<4(=E(+A1&/;:#DH1GH8<F7G#+#5&:E;=78C=%D.(34810#CG'
@r5957
ACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCNCCATGTACCGGGCGATGTTATTGAAATCTGCGA
+
G,6#H)6%81D8=B=9"0D1"H4D*'#*<6)3G/BBA4HG"DH!B<?/CE:E,<1(1-@!%5F2818(
@r5958
GTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATNGCATGTCCAGAGCTCATTCGAAGCAGATATTTC
+
D"#9%(!E->)/13+H7?/D<!3+%*$1/EEDH#93D7764D15#91:694?,,,!4,0'5/A-D''>A(,=@/";H>H'!&"D&291(8*E@@5D1$,5E<F3.7F92?@+;@"?;#:G"<+C61HC:AA?HF=!*@'6@>:/C-
@r5959
NTNNNAACNNGNGCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGNAAAAA
+
")"&!"*"!$$!%"+!%+#&!!&#)("**(%)(!"()''$"'(+)*#'%"(&#(!!$**#)"(+!(*"'&))&"++#!#(
@r5960
AATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAANTTCTCTCATGCAAAAAATATGTAAA
+
?D?$&=?"-%A>?529+#+*3"8,$0F,-?B)5;)9;"5.<90A+!#)FF<=$:?>:.2*;.73(6'=717D4"=%616#?=F@2C)A+F9*>D,,(D$H:
@r5961
TTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCG
+
7&(6>="@"4B22#C%/%&58.!1&:#4H<3!&9/>;H$*?>>01D3),GH;;$.7?G8)9%F'*(3&1(2"=,H!4'A+CG'6#$,4)'7!D"C9/F/9B!
@r5962
TTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGGTCAAACTCTGCGCTGAACTCAACANGCAGCATACTGACCCGCGACGAC
+
7/BB%'<A&1E:2."8%1!B5%<H1:C(?*<&.>'(A<A;(,.+(/E#.3A47)>=&!6.#.*E#:*)'.0.&C7?48-3?%26'&"'/D>A
@r5963
TGAATGGCTGTACCGCCTGACGNGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACC
+
EH;(H9=<@*#$A*)CH#;D3&1!.%(!4$H6(:3'/+88&?<.&.?7%>6"07D0='*3G:$6H'!":><83.*B10?8#<F$
@r5964
CTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGC
+
.3%+%0F3-68647A7(>'?'5>G@-:40+!A1:%/2)>@.F3C5E8#$(=(-AF5+&+'+.9H+86&=F&6F8.HBF9?)-+@'.2=F-)#=:F;FA&9
@r5965
NNNNANTTAGNGAAAACGAAGATAAAAAACCGACTTTAGAAATATCAACAGNAGACTCAAAACATGACNAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTGAACACTATGAACA
+
"#'('+#'%!)!*!%)%)$#"#')(#'"!"'"&##')$+!'$&%&*)*''+"*%+*!(""$$"+#")%"$(()(*&""+"+"$!'!*%*($)")*')"')("$+!'!""'(*&#+"&%"+*#($"%)##$''
@r5966
CAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCAGGCANCAATGGATGTGTTCTGCCATGCGCTCCTGAAAC
+
C)8@+HA8!&EF(9:;&D4H;@(1%E#)$ABC5!%37(4B331/+(*:.2=>#&*E%417!'&/-:9;%4=.>44
@r5967
CAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCAACAGGCTNCTTTTTTATTATTCGC
+
52196#A4<C+$2+*$=<%>8>!8&#?0<'3:5$>52*%8&8$C1)+D>DG#A9A-@'7;4&$3$229<(,>AB;:"E$F3*2-2H&"C3,5$*32"2C&-G*$AE1'B8FC<51=/-/EH"30:-##EC,H+F/2.+C&(F6B*>0<%727&27)5:"(%89!"17)5A;?7">31#:0%*$+$D&2.-A/&B2@FE6@
@r5968
AGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGAC
+
7/DF<6<:*73)#*""25'<?=F;*H;$$/#GB38A5"F2D3);%C0
@r5969
GGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAG
+
CA;G-#<8G!A:12(%=<):E%7ED=0.00+G-%7E22.!8>#("@$/H:5DDF7.(*H5H@D#'@FB:
@r5970
ATTGCAGATGTTATCGACGCGTCACCTGACGCACNGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGTCTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCA
+
#57#=4A>.&=%4-&/$(G!F0!BF3+93?@>20/F(675AAC8"-DB."%B:"+()0,5(FG;H@=F9B;/'?489*CECG6#>DC8;$CA@<F<268@@*/:$C.H,&09#,;'&E+4.0.01+)!F*;*A+./%:EC-8>A%2%2..;/0#E%@@""/CA:%6HB
@r5971
TAGCCTGGATTTNTTCTATCAGTAATCGACCTTTTTCCCAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGNCATGAAGANGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGTCAAAGGAACAAGGC
+
A+H<+><C4(#>'C'9H*0G,:%@&B9?0&21"@,6/8HD>>)#,$*1)+/BH8D%A@B'<!G#48)DB7CAB'(&F6=G,',+"4@G7>+84CH&*7'>H7696!:5!9$)$A.!)&:>%$/:"61#0)6?;>%-
@r5972
NGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTAT
+
#.+8)*:;7-"'9A.)G25#.817G=%3";/;E$.$89E6
@r5973
GGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAG
+
3(+!=?+4G(EB+:<H>D8+<$+'&D(5?*2+A>A4+6!,#6,*(@(=!;G.B)"G*$"D+%$H9/=FC'&B7')"/@-F9F04C</94C+7&5$==C45
@r5974
CCACACCGCCGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCT
+
1D")H%0*,<#C2!)=*A)@+*9FC6.>,-C*GG?=<HF7=3-3,:$51!0G$-</$3#F<6#H'#"-4(32B;$F#,,<>1'9)/=818AB#3!3%$1:49(70$#'
@r5975
GTGGCTCACAGTCGCTGGTCCGGCNGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATG
+
;,%0??&(:,!+;+H@@"D9:1++EG$EA?9%50/D3'7.,0;D>.#5;3(8,C80=/40/:8.4<9(-
@r5976
NNTCGNGNCACCGGNGGNCNGCNANCNTNATNNCCTNGNTNANATNANNANCGNNAANTCNNTCAAANCNTNTNNGNNCNCNATNGNNC
+
$$$#$!"##"$$!#!!"#$"""!"!#$$!"#$!!$$!$!$#"!!#!#"!"$$"$!##"#$$!###$#!#!$#$"!!"""!#$$#$$#!$
@r5977
GNTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCNTGGTTGTCA
+
)!299!&06@*042E-CEB(5(':B>?%2G7'7E/.<C!G/:8C(G#H..:.4#>*$;-=@<G)$=.067CCA>6,D%-3/3.1->"
@r5978
NANTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCT
+
&)")&#7<>2G(@H4@!/%=>B2:DF7F57F1,'+7C?>B5".@(<)32A-=*
@r5979
ACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAA
+
@&6+#(8ABB%?=6!@AH;(%!,=>-G..4(C$=!#>:=E!!0%E"(E6";56;)(2&!G/-0&%G#12<45??%5,4?3&'=8,3,,8BF"?HA-916-1%?8,@D<HB0!5*;<D(2.@=2B<
@r5980
GCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGNCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTNAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGT
+
8?F+E@6H!%6@-'3F,+6280/4*27/8:F(/7E(;*64?'%!&$-;D;(.)831(8;?AF&88$1!)F;D5822AB?'0(5:C4!30%)##+*%C@15087"D7(&;3*BB&('18.,?=3&F5%E!2G6,/<)E>H,#3;.=E#.:#=;)-=.?>@%D.1':(#C-(.<(;=:!74-,$!F>2*(B18>>5G,
@r5981
GGTNAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCNACACTCTGGCTGATGGACNCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTG
+
&+!!)!)&)!'$)+%*&+')(#$)%!&"!)!%!*+"$'#$!&($)&$"'"+)("*!!)!%%$$""$)!)'*'!$#)"+&++#(($+""("&)%)&$''!*!%)"*!&'"#))+"*%!'+&*+!#"$(%+!
@r5982
GTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCANGATGNGTGTAGGCGAATTTGCGGAG
+
7-:9$2H"1??-?330.>;(=@<D@,(=41'%$2A1>$,A<C+>-.4=;:DB>5/G'H(H5#!"001..>$-%%8((C/=-9@#GC0/?B<C!19"@+<EACH(<>4/+&-/7,/
@r5983
GCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGAACCGCTTTTACAGTACCCATTAT
+
$+3F.)32'H=>-G<2#:0#@+:*&@8&"92>&9?E7H.!15$8,77*,76/>A/GE)-67'8*(>"/!)6>-1FB0!*HG&G/35*52?95!<%2>->A#&0FH62/=%F*67F&5*.'$B58<)D!4E,'53=4$);G
@r5984
GCCTTCAGAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGG
+
)08-+*C9':$>"2'G,0!5C+:@7.1DD4.(!B+*@8-:6-1G5BG1-<F!>C9";?:7>(F;:)#$9<79!"0"$3H()8F!#%;7'>/$H*('7&.'C;1CA',@441%-F/B+31F&=%&(/;<,1+C/,3D+D-:6B*@)-2*
@r5985
CTAAGTCATTTTCANGTCNGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATNATTCCCCT
+
#''(%'*)*)$%)&%$#*#)#++'%*($%*"%"*#+*#(%$)#("'"!""$')*(((&!*)******!'%&&'%)!(#&!++%'!+''#%%()(&&&&"+$(&*$+#""+')$$$$
@r5986
CGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGACTGACCGGCAGATTATTATG
+
)+"%!+(*''"((&&!+'&($)#**+%(%%+#!"''""!!)+%)++*")!")*#$#!+%%&)$)&($
@r5987
CATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGNACGCGGCAATTACTGACATGCAGATGCGTCAGCGTG
+
*;(-;3.@B>@(D8C>!/&38564/F0!HF7;/G<)HD.5AE'+8!71?4%$B3&@BB-,)EED;:+7@*E&58;H56:D>04@D7;%)70$)+"E;5E7!1A97E
@r5988
TCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCATT
+
)9&4<?7&9/"9A8F0?!?2@(H99)-,H$968F>#'.3;&8!*+DC>H3B2EA
@r5989
GGCCAACAACATGCCGGAACAGTACGACGAAAAGCCCCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGC
+
"/:<?<,*E:EH4F%<%:6/6H4::4+@&&%HC)5?--3<B,!*%F.#B*8=;0C4@*,,=(D";F&-C43G*9>#+"8=*E!E:4'=&.0=F=A?1C?3"&
@r5990
GGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGACGTTCCACTTCTGAT
+
E2G#8@:!A48$E#"(9A0A%>/*?-@<6-3C/:%9?.>/H;/3$E3DD2B92>DA$
@r5991
GCGNNAGNNANTGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACGAGTCAGTGCCGGACGGCTTTGGCGGCACGG
+
#)*"*#!!$!##+(!)"*%))$"&("*%$%#+&'&%++)+($#!#"%('&%)%+'&'!!$+&+%*+++(*)"++++")#&#!&$"&#+$!(!'$'!*+#*"&(')((%&&
@r5992
AAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGNGGCAAAGGCTACNCTTANTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTGCAAATGAAANTATGTTAAACATTGGTATAAAA
+
<8;--'$1D7**7+8=>22&B%#:G'9-D$=H/2"(3=#(-?5%(F?"3+0#1'7)?7H-8-$:*.HE5A@(03(F)&G)3A318H.FD$;8'"7//)7F,*-/*="%47)D),7C;'D>$EC/"4/1#)F%'C)65A!
@r5993
NAATTTTCTATCTTTCATCATATTCTAGATCCCTATGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTCGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGNACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATA
+
#93D6;3E"/CA?B227'43"#9C;(*8B#EG4..@=,C!<2:D>(C?8DC'GE@6(+0366<29A9D214%@#%'EE*>@;!<6.,;E#'A-<6?E*"10!,F:0%$831A:+".A,H9H+B2942<9"9@07D>G9(A)ACCG94"3-7)E87&#F!119A;4EB@+9@F=0<%2G2=1/)&;8B@E6A.5&#6()!7+$=H?,8BE2&#DE20%H++'%2$8C,G3.=6E(CB(EH"='#;/G-/(;(5<B37+0E4"4,H.'.9:+.B:B/5+*75-*66H12+*4;+#+$(2@>BG00B(F>"&.5*83;:".2.$CC)5DF:.CCE#2>*,)@6@%65-F'+99D,?6;H@E->30<:9*/?+C<BHA3A(@?4E/?$6#<6C%:.8@91AH-;3)39DA73E93G5A$
@r5994
NCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCAGCAGCCTGTTAACCTGACTGTTCGATNTATTCACTCAG
+
$:='D4AA?;9"*/G)!H%>&F0B";)>>>4>.;C3C=F4B0>#256;6D>;&8B/E-63E>?G#,7B856=*806
@r5995
GGTGCCAGCATCTGCGCCACACCACCGAGCACNATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAA
+
=F@@(09$/'%$/A8<8?($2C$C"4%CBE&'&<B=$A-0:B7>BH(6;(H+195.B./!=5G+2:,8<"&$G(D"0@3==E
@r5996
NGNNCGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGANGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTATGGA
+
&)$&++*&&%#'#%'%*)%%(*(!'*+*$(&!($$)#%"%"%*$*'"%%"&%&&"+!**&)))%#)&*#($'*+%'*$"#!(+!*%*!&#$&'+($&((()'#**'+%'&$"$"!*'+)"'&%***(*))''$%%)"""+(&)(*$'&"#$#+!(('&!$
@r5997
AAAGAAGGGACCNAAGCCACATTCATACCGGGTTTCACTTTCCAGCGGA
+
:9%!H.9-3@E95AE9'!,=B@./$H29#++=!5,$"9/376":-8H@B
@r5998
CGGTGAATGNAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAA
+
A2'6%8,4)0%1G0$A36<&:-HHC*3%"H<A.!("7*$+>==?B38H39,:4-=,+(&+3(3ACE"3<EFH!@.4>?E!%8'
@r5999
AGATAATGTACTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATNGNGGTGACGNGTTAAAAATAATATCCTTGGCAAC
+
%G36B>7.3%?660%F?9=+D,&<<C0'6@C1EF!45<H;/73'B'47@9F2&E<2(+(F06(68<'E@C,#4;1G2*,5,3C;46/5:;%"1B@6$8
@r6000
AGTCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTT
+
4E8,A!$/,84B?.1A@F98"#4(F<,/#"6,A=)/@=@%<.5;C/3>HHG0H!H+>E(.+(8%=+=1<<*'-'6C9'0<8232!*.+.<,1;G1DC&C=A>"E@9A&!%287;<)/,:"?A,61*C%<D5%(F("?C=@GG7CC<F00;9:+'A!E7<&C'D@:94C)34%<8)8:%=6
@r6001
CAGGAAGACAGTGCTCATGCTGCCCCGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGNTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAG
+
F<'AF4=!5<0=D:!):8<";G+@(EA(-)*,''7"=5)4G''&6':"9A)1AAD%.+$3"8>)/D+6(-H(0FBA=E#8?!(;DC"D,H(F";(*7B-,9,;3C/*;>H+9E;,7/:"1(F1<!6@7+2B9F.16-84-('>3AD)/*;C60;)5",#G<1""C6>*(>!@F(+C)
@r6002
NNGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGNTTCAGNTACAACGTANCGGTGGCTGGG
+
"!BE53!>9-8GEH:6$?/+5%:>#26E?%81(3H6H(*D9>A<B/;2#'1C-5A3"&&8D$@3#<?<6-#$-G,9#(D<!(<=1<A#A!(.+FD&C93>GD4E!?:+7
@r6003
NGNTANTTCGNNGTNAAACCGTNTGNNNTNACGTCCCGCCCGGCAATCCGTACCTGATACCAGCC
+
!)"#'!(*$&&*&)$%(#%*%%!&*%"!$#**"+'&!"*$##)((!"&+&#+('!%*%%#+!!)"
@r6004
TCCGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGA
+
-%"G#GC*@?0.-=E($E95@A)=?E2383A5;@CA(A15:7=*1%,@34*.,6A)H<F$/C.9"';-#?8:GC)AE0#,C6!F$<<"::#*$#8;F(,<5:6;>
@r6005
CNGTTTGNNNCGTCAATACATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTNCTCCATGCAGAGGCCAATACCCGCGACATAATG
+
&"("&"'!)$'+)'#*%$!$')!*""*#%)%%!$*)%+'%'#'"+*$&+))$%#""&*'+&$$"'&))*$&!""+#!#&!$)(+*%)%&!'+$#+(((&"'$&!'&!
@r6006
TTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCNCCTGCGANCCGCGACAGCACGAAAGTACAGAATGCGGTTTCNACCACTTC
+
<#H*5(:9?EC;5E153+@@A"4,,?=1$#9&,'A&C.<F3&54!E3-@#3=F+4.BD&H&,?28DHBB'"56?.@)90A-C"<=*$+?7=+.!1)!0B2H+5,!G-A-7/8+E?>$/#H"9E%'FHE%G:4<0*.B+&!'0A:8*8*G%<8D51BBC=!F/BBC
@r6007
GATCCATATAATNTTGAGATAAAGCCAAGGCCAATATCTA
+
>1H/G<#)=3-:44!.2,4&(7$>,D%/BH(?+*DD:$B1
@r6008
ACGGATNTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGANAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAA
+
/<=5$D:4>6.;4/;H@1F(';H<A<;"%'6&;$8/51=!,?<,D!:(//(>>73!#""!%9"./CA*'4*5>"7%H(91;+0,+A0;#GH&(5-0>$H$FE"%HF-%*%-&((<&#D6*&@71108E.09A,'-!'?%*!21D$4E:H4A@:1CD'0"D.1=3A'D<;;AE
@r6009
NNNAAGNGNNNNCNNNTTGGGNAGNACNNNNNNCTNCNNCN
+
!!!$!$!$$!"#$#$#$#$"$#"$!#"!!$"!!#$"#$!"#
@r6010
GACCCCNNNNCNGNAGGAAGNGNGCCGGGCNNNNGNANATANNTCNNCTAANGNNGANNANTNNAANCNNACNANNGNGNNNTACCTTGCTNNGNANGNNCNGTANGGTNA
+
$##!"$!"!##"""#$!$#!!#""!!!!"$#!""#""!"$!$"""#"$!$!!###""!!"$$!!$"$"!"$#"!#!#$!#!$$"!#$"#$$!"#"$!""$#!$#"$#"!"#
@r6011
GGAAGANTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGA
+
,$>*$>/73;(2F!8FDE#.2/$4)8+=(48/=D%09HF/-A)&1B=-88=F8!43(7!=AG41?F.98">F90G/,,+F
@r6012
GCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCGTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCNGTGCAGACAGCTGGCGACGTTGGGCCGCCTCCTCCAGTACCACGAACTGACTCTCCGCCTTCCACAAATCCCGGCGC
+
80F2(%CG()098GB@!.)5<618*2G1-:8!?;;+B482695CD3?.8?E2/;+171$"+<@2*.;):;1.50F"8(HD.F>EG1?:0E+%&@)"C;<6>>8E%!2"6+<*:,E"@'9D$<@@$(D9);E&.>".:;<H+4?779@,-(08E4G=B*C&GF:4D"&G"5A5D.%/>72&8*D!8#4>*C'$6&H53;59%!@2139@F217F1E,@0FF5D=7<%B(,4#
@r6013
AGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCANACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTGGCACGCAGACTGAAA
+
;EAB!.+%F:#582AD!4+C9H#1</7=1'-%D'(?D5&>*/*(+.>GAC$+BA9=9!62?0B;;3B%A,#1#9'';;47-61D>5H#&=()6D3.7=
@r6014
CCAGGNACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGNTATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACT
+
A"A!:;1,!!;@D=F9HG*!2)-).C2.@)@'?4C4B&<2G8$"60"B/4).#(E<$?D8%+738'/%*H@.G674".0(80G:-1=$%$-%8:8,D&&/92@)C-@5'5+)+H:B4B2?372&@+'<%.8H5
@r6015
NCNNNAGTCCNCGNNGGGGTCCCAGNNCCCNACNCGNNTNTGNTAGNCNNTNAGNNGGNANAGCCNCCNNGCNNNNAANTNANCCCCNNGCCTNGCNANNNNTGAAGNNNAACGNGCTNNCNNCACTANGNTCACAGANGNCTG
+
$$$$!$"##$!$"#!!$$""$$#$"!"$#$#""!""#!"!#""!"#!!!"$$""""$$#""!""!$""""$$"#"##$!#$"#$"#$!"$#!$##""#!!!!!#""$!"$""""$$$####$#$!!"!""#""$!!!!$$"#$"
@r6016
AAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATNAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCTACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGNACTGGATTCCAAAGTTCTCAATGATGCTTGCTGTTCTTNAATGGGGGGTNGTTGACGACGA
+
"+%'%&%+!++#)"(%&%+()&)*)"%''%$(!$&&$!($!*!"((%"(%#'*)+"#)('##%!)!()*)'($(*!(%$%%)&&%""#)*$)!$'"("+!#$#*$*&(+$!((&$*#'#!"+")#&"+*+"(&#"("*$()+&(*+'(!($$%+"!"+&#'))+%"!'+&"!"""#&#"(&*'%+!&'!*&$!%"")!$")+%$""'*'$*$"$$(%"%+(!*+*!!&'")&"&!*+*()(*!%*$(%+!+&(+*&"'*$''#!"!+&
@r6017
GTTTCCACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTC
+
,)&>G1GC((D$D>;A7%F5A3+8%")8%2$7?4-D'!E$=7=
@r6018
ATANTTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGNGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTNTTATGATAAACAATTCCATCCAATTGATTTAATC
+
H8F75=5<4!H(C,!)C%8(;15*9C9&E3G!'$?!C5.;<.-;*'A,)8"9BH#G(C54?60>$2#A!2C31$<46:6D=(B-,3/)".0=3C7!=.@*/%D5FBD"&9>$+2,.*7><+++/7$>0+>/E%8!'1;6'<71/(G%'/$>1/G4F;C(/"#+&2;=2?;4%*;?">!9#
@r6019
GAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACG
+
*G03.D%'2#$).,D#'%*>$/;25%@<=#2"9?2H7G+>6CF,1H".A03%<D11.C6D#8,;41F1G%*0G1?.;.-552(F>C/B<9&2%/2+2;#C84E/@CH680EG#20)F@.%26)0(%B$77:-@1"##4..<2:&$,:;*6A:>@=@&+D886)#HH;G=$*2BH
@r6020
ACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCCTCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGG
+
)3A0!3$;>,:4>@,A9D+8H!15$EE",10+D#!9*G./H;9(*)(4:A>HA1%1$A@2G!8$&=58.B@;'/*/+8071C8A86A,4';7D/HC3"(7,%>98,D$0"1/E5#>@32"?814@&/(7GB$7=("%-(#'<.?F)E99D3*!)8A9"HB2=E5$H
@r6021
TNNAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGT
+
*"&$#$++$'"+*&(+"+)+""$+%#))"')%%"$')'*"#%*('++&%)*""+###!"#+""&+"+(#(!"($%"%&$+&$*$"#&$++*
@r6022
GACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGA
+
.47/G3C?E6FG@8%.0E(1/2B8A@!0/C"0C"3B*(*155
@r6023
GNCTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAG
+
).:E2+<EE$5@+ACE-5;*$@G#%"9@#<12<,.8&F.DH2<.'@*,+!+>-!0HE
@r6024
NCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTATCAGCAGCTCGCCCGTGAGGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCAT
+
"792F&%'!((D9:,E4B-5G8%#1?:?A#;F?5=/!$?4127H(ADC@=B9G06"*6D%,F@01#<BH&5@@$;);&:B'C864G<>)GH:@09(CD*#=*AE,@E,E4%9'5?.:+;#H.D'<*G3*#8A1!C54.;!8.4-#40"6)433HF1()*@*>$A9;
@r6025
CATCCTTCCTGACCATGTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAANTTGCTATAAGCAGAGCATGT
+
3?4F@(D"D;1@&82F6+60AA79C.-(AF9?=7+=C=>1C;D&7:D'AEF(7&4">2$8E!*-;F;/F5=C:@*,@B%F/%;@2@$!4>B&E
@r6026
GAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATG
+
8,4+.'$>;-G;&)%<&*$EC/=%C0:D+.2&6ED%4BH51";-.!7*/3@
@r6027
ACTCAAAGACCTGCGNAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTATAAACCATTCCANACATGCTCGTTGAANCATACGGAACTCAGACAGAAGTNGCACGC
+
+'+"%$)(#)*$((")!$&*)&)%+)%("!'"+"&#)$(&"%!!#"+$%)'')$+"+%))'#"#'*(!!%$$'*!%$#!&+#)"*&&+%&)$$(+&""$!++')'$(&
@r6028
TCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCANAACTCCATCTAGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTNATTGGTGAGAATCGCAGCAACTTGTCGCG
+
EGGB%62G/BH+A69F%=3)"$>$84!0B)&<GHD&8&%%;2.G*H/>#*,(=?8H5;?7%14#?B86>8==/@9A?;8D&E+3#-()#FAB)</-+%5)2?)&?5H3C?+$&&..#@FHE=(6+%D%!44&D'F3@:&&)6B2:>>=DH&<0&FD+,HD1'#?,78AD;7
@r6029
CGCNAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGANCGGCCACATTACGCTCCTGTCCGG
+
*!""+"#)+"!'*+'+#+!'!%)!#+%!()*!)*!$'*&'!'*$+#&)#'$%'&))$!+)"&)$)$"(
@r6030
CTGATGTATCGATATCGGTAATTCTGATTCCTTCGCTACCATNCATTGGAGGCCATCCTTCCTGACCATTTCCA
+
:H.B">:,4%2/H9#).0)72""27+;47,)4,H)=AD#7C/F*=05,B!+%EC012">4763+$839:>-#)!
@r6031
TNCGGNGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAA
+
"!#)'!"+%()!#)&*!+'*%!%#*('$'$+&"*"'$$""$&()%%+"()*!&*!#&$"#*'#&&+%&#)#$(!#+#%
@r6032
GGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATNCGTCAGCCGTAAGTC
+
,.#4C'7+0D!%)6+3=E/A,30-34.0#-2"+!;$?!;A+96'4+&/C<1'
@r6033
GAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGA
+
B3-;47*':3-719-C)H.$&0B?H$#D/.=2/)ED&9'.$D,9,>HF@F'EA(@%3FC6<*>F2/!HG$#6B2?:1')1;A4.:C**;B8:6/.B#'
@r6034
GCGCATGGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAG
+
H&6='E0?C:<!91#?=#"+@$4)#-D?G#/A%99G1F;!>#A**7"**8481%<06?*+/>0*964"62>44&/1<(=H/$E#05A%??.#)>*.*-?>/FGF:A1
@r6035
CTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTAC
+
59%72B2(%C0!<7';::#;)?-<A3F<>,HB@@:65@D!5E#;?%#,?0<G01E+0C7<6:<:$*/3H<4C:A$9
@r6036
GCGGGGATTTCCCTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGNCGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCNTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAATAAAACGCTGGTCCTTTCCGGCAATCAGGC
+
G(,89!.8E*F@%801A@;0,B:@A5CA2H.0!$6$E?=?84+0B1@CC6636)(F'A&,66$*A0FE&&8F<=8FA*;E;8%5!0*.;E?)6>E.C&7.=:)&47=&E3E6@D%+9$8$73+DG>,(BFFB/.:<A%,3%:FH5/'8E39E4<%@/G?A):"C:F<$G3C.&D.--".&!27!7!G5H9,.3"0-:;+;,-#"76;!6*4:@((&H7+>/,?E99HF2-#%74)@4G(88H:;EH75E'7<-*DC?EA6/$@)H=F8<+=()8F*3+F.";#2&:2)A,G%2A:#H3+-+4:+/8B@
@r6037
GNTATCANGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTNTCTTTCAGGCGGCGGGTC
+
*&&D(&(D1H-<.HD;!/"81%1C7+B-!46<'E4,>)(@%0HC''D2=?9,B<0:"=H*"7DD(4G2H4+A%D8;!?:F%>)H*'>H%@"8*<"#>98"367=3=5#*0BF
@r6038
GAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACA
+
7?;69%1,#2;F&#0=4830%"BHD;G39G->A0BAB+;D$:(1>+E@>9*D6#<?AHF,"
@r6039
GAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGNGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGA
+
7!'')7-'3-79$+<1"<7#<7%+G@$C('C<8"9,)<G0"!6%$$E1%8C%>B>AE"(>>/5FAC59<*E70*+&;,F3*7;F:=21<$(!7-0A4/1@&012"CG)9B8F9)+63D4EB2#E:!7.!"5=-G;.!?/@#67&>F0G2.>E8B+FF35)16#(;&$=9,1
@r6040
TATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACNAAAC
+
=,0)F<46'*,GA5+B1B:;&8#@2%!:..;56*;9=$@+:"&%?,.?()*;(<+$G1$
@r6041
GGNCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGNGGAGAGCTATTTACTGATTACTCCGATCANCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCNCCGGACGCTACCAG
+
'("))++#$&"'#+$!+*#!+$"(*'+$*)!(%(%$'')"(!&"(&+$%!!()+!((%!&'*&&&!'"$#)()'))($!&(%&%+$(!$'$#&&'!!'"(&*+%&!!+%)!)&*!$!#'$&"$)&#%*($"")())()*+%$!&+(!*%"+$*&)
@r6042
TTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGC
+
2)$*#DH;F(*=8(.%+C!.!0%6@2,5B>CG*3"*.#!(>*6*&-(G'>3B5;3#@D?F2)&.6G5/A(<%BC%
@r6043
TGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGNCGCCTTGCTGCTTGAGAATATTC
+
5HF9A?D,'65B/"5;A&;10B3<4C7,#;C@:G.%/$%<(1E(CE;5>B;G4#:$1GG*;=,<E0*)$
@r6044
GCGTTTCATTACCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTT
+
:3)?,>:$+0=D6@>+5;A<>:1"0A6&5E<1-#&A(53&612AD4,>3,=(-(@1$H6A9".GF-5-$
@r6045
NATATTCCATGAAGGTTTATAAGTCTAATGAAAACAAATCCCCAATCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTTTGTACAAAACATATNGATGATTAAACCCAATATT
+
!+"#""!%&!'*%$&)'$")&$)'%(+#$+""($#)&)))'(+#'(*%*(")+'+&%+%#)$(#*%"+)*)%*+($+$*&*#%($$))+""'(!!"("$"&""'!(!%'(%+$)($$&(+*)!*$!!'+**$%#!!*!')+)#+)%$""+)'*)'#
@r6046
CGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTA
+
H##3'HF"?//@*4,@#1$,4:;HH.8!'2<F84$0H('#FG/4'20F//92#!'FG>&C*C:A+C5*;2.51G"73"6=CE#5;744$,8!$<G(<9?9-'
@r6047
CGTCGAGAATACTGNCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAAT
+
D<(AD?@B%,4$9$:+G2/!1>90:&6(>::&4A!2"E%!(+->C!GH'+-7.7%9
@r6048
CAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCG
+
@A#0,B@@FF>C9H4<6!HCA1..-1'G%2%/-!#*;@F0=*C3B#
@r6049
AGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGNGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATT
+
?/=>&D?01@<AE&C+'8B.>)7!G"53A#2H@G::&E3F14-<%EE-.F"8#";?+C&.5)1"A<7A:G'G!/B"
@r6050
NGTAACANTTATNANACATNAAGCTCTCNGACCGTTCCGCCCGCTTCTTTGAATTTTGGAATCAGGCTGTCAGCTTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAANCCCAGATATTGCTGCAACGGTCGATTGCCTGA
+
")$!(#!$%&&(!$"##"$'*'!'"%$*'$(++'%)$#+***+#&"""%)$+(!$++*!%#*$%%%)%+(+)$'!!(')$+'&!&#%&%*$!*+&!!"!(#%##+'$+"$+%('%#+$(&$&&"+$&'++&"+)"'+#'#+"+')!%
@r6051
NGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCNTC
+
#D'7CD*!C:0#&E8'A7>9,!?131*G(#+-(B;9:D7%";B!8?'0+:
@r6052
CGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCT
+
%C>60/3A*.2,A1/+)?-"2'H&/.+8HD&."D()/?B<?&2FGG>$E@5/543)'<*B.&G065<EF58E<",F66.77F=D=-3*00A3)GA!6E:;80:,
@r6053
GACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTT
+
G8&GA843*=)75=(@.2H(-FGH%*A#:;=6*C30.ED8%H>B7(=/8:+-@=;5>F6("98+0G"<+)
@r6054
ANNAGANGGNNATNGGTCACGTTGACAGTACGGGTACCTGACGGCCAGTCCAC
+
")$#$)&&#!#')"+'!+!*+)"++("&'((%"#%()$%+(("'&")$")"+%
@r6055
TCAAGAAACTGATCAGGGATAGCGGTCNGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTNTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCAT
+
00!"+=+"DA/*1.#%C3?:F:=*?D5C.8AA/<5!DE>A@5+A@'C=5:;#"4@#,%H>;(H#.$A$*$@(.E39/+$>;//>D7<B4<<<?G!C633/0HC7.C:D>=F-)8+$#)G*).<H1!H,*/(3.*($A"#B;5FC7+7?:C;1C&%2H)+:'C$12,0=!"?9:&<)!8BB"=-.A,$A1H""<45;0$
@r6056
AAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGAC
+
<'7&$'3$B(,("'!8F@2$F%+"7;>?A9G$,.&4%A$#.,7F6'2<;GH>F*,(5GH@D'9G7'
@r6057
AAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGA
+
G+A$4"+8;4@4',@(/;*1'*?)35-(9&A(-:#8$=?C./D:;0.BG)<8?@A@&"26+/1>G
@r6058
AAGCGGTTCGCGACCAGTAGATGCAATTATGGTTTCTCCGCCAAGANTCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCC
+
HAB$13:+:!;H2;"4:9$-.B4=**2D.,C=D/'#?<$.#)'>H:@62?+8G?.<%E0G$7*)!A4(?'@E$$3"$0)!8>:D5*<
@r6059
GACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAA
+
786<GG?.E1&GD"28D'"GF5BF2.%"4/<3(=G('+7C<1
@r6060
TNAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCN
+
)$(#+('!#!)&"%)")+*(($!$*)%!$)'"&*%)&'"'!)*#)'
@r6061
CAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAA
+
;"(01AG;9A16&$B;G(#F7=;>=5;,.EH>39@!,6>8*8%37&:@F>#5.#<81$&,
@r6062
CAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAG
+
4<493"(G2D.-2(05%E#@E.(%)/8BE2E#+1;;#2>>1;C+'"=:
@r6063
CATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCAC
+
8>A)"E(E1)=D7?!$9!80299/24/-&8=+A/E9-<?'98GA8GA!$H<)C.51G#6G2"!?E"7:/'3'1=$8.G%8>AABGF/!?4.F#E*
@r6064
TGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACNCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTTAGAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGC
+
*3%#$H@@.0,!149'FF8?%8()6D!!*38:%>2'@!3G$60#FG5@FD81*%@7449.13)+&5<EF@D5E0=8EF:(<46?$B:H@9;(-10211(@G/F6+&&$*F*/;A92&!0!7.A1BGF-?)1!A#?<>+%G<6FE,GF(?'.>"6>D0D2/F'C-:"6$A,G&=4)*(BF08C15%0$:*9G&+A@6.DE3%:+)';/77@=.*)$"B1677*>E9#<4(23G)1G,$7##B47/#(57*+!*+-)'H=;@*<=&A#;=7B'C%?6E*!<)0'%>D8.=$E1DC?348D4);,'1*7@(H)B2@!9.D?D:<0%"!"1
@r6065
TCACGCTGGCGTGGATGCCCGGAGCGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTA
+
6>#&E8B9>+0:9=AH2(.CD5#:7=91=<BH9H8!D#C=*!=!-<=>E8,#03&-G=$=#(B:?9):.:H',D#+;DC
@r6066
CTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCANCCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTG
+
<(A)8#B'F)$9E1;0447770.5?*7?B)4AH2B&=$HG=G<!GG#&9""8;3@@?8$&=B+*352.454/.8=+-90,1@1-C?1;
@r6067
CCNCGATNTNCTGNNNNCCNNAGGNANNGCGCAGACGGTCGATNTTTGCAGACGTAATGGTGCGGGTGNTCGGNGTG
+
*("$#&"$'!('%""#!)*!#%*#"&&!+)#$*&$'*(!"+!!'*%'$'!+%)"%%*%')!()'%"+*%+)+&""((
@r6068
TCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTNTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATANATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCAT
+
39/%E7!CC4E1)*4?5C&&A#%D"4*)+$"E<C")F<#..*=2*6,%,?$##F1$A"D1@2)1)$$=8(+"*G+C@,$GC:"%31);A;+$#,/A25B180A9>B34*C*6/;/?+'H$&%.,CH':%52:8.=$EB&71>6&.;BD8/&+5#&#4,6;,?A%";!&<=G:@6'@@?#/:.)767G@2',;$5&71#D:FD:C:9C&"%6F4E)G26B(B1/=0C&C-=<;9C*;F?E)"(?F)F.F?$@#)3)()+>2H"C6>6F=G03!6*%'60:E>&,4C'
@r6069
GTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTANTCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATANAGCCACTNATGAGGGGAA
+
11HD$?+:"F!HD<FHHD,,B@B#C;!0FBC,5--&+*,8C:<=(0$/D+0.>.+$'%-F#BE?7$36-4FA?)H47$5D-8$7(2*7$G:9*);-3FG?,,&4),1&)/10(=#4'
@r6070
CTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAAT
+
&*<'@(($E7;3>E+&,D3.GH64):<,68:F#$/F-!%2E0B15F@(7?GE/:3=<
@r6071
CCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTTTAATTGCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCA
+
BD<1@"><!08%@G7;,8&!)&G;(>0E08#EFG!!"(-+)-#=671.F+7D0B*+3+BF#9,-8&D&C?-B2&F%6C?2136/%(*E@H8B4<61H-.4)G#8@F<:6/?2A97@>4/2H9-$C6(H72+-%"BA=A(@.D+5H57$A,
@r6072
TCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCT
+
!>,&1.51)!*:.DH#,A30%37,C#2(??@)&A8E=?*.DH(7$%!'1
@r6073
NTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTG
+
'(*'&#'+!%%&&&&(&*#'&)!#!&)$"%*&"$'#*!#$*'#
@r6074
NAAACCNCATCGTCGTTTGATTACGGGACGAAAACACCAGGCAG
+
#+7!A+H3E2#;8$#C-1E2:79'<.6420/6,<*#E4@035-.
@r6075
CAGCGTTATCTNNNAANNAACGTTTAAACCGGCATACAGCAACA
+
$*'%'"#$("*(%!$*#"*#&(+'$$&#'$+++)&+$*!#)*&(
@r6076
GATCTTTGCAATGATTCTTATCAGNAACCATATAGTAAATTAGTTNCACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTT
+
.?+#-$)E!'FF$!4A?=%6#2+;/F5E&"->!&:0@>4/4+D*'>+"0>?5G#C:<>39::,A?&A1*9F'181&+0$G65#5G&7'A+5*;<DA>6&9G
@r6077
CCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACA
+
8<*9&"4:/G4!915D3C+-!;!F97=<F36,>8B3)H7$
@r6078
CATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTT
+
B9C#D(HG#8H>%+B%60"E@#6!)/@4$;D<4(4&7%$0AC
@r6079
CAGCTGCTCACGTCGCGGNCGTTGTGACTGATGCAACTGACGCAGCACGCGCCGCCAG
+
+!&%%!'!+&##!#*+)+%'+!!+&(!*))!)$)"#%*+'"'$(!"&#*%&%&&%#)"
@r6080
GATANNNANANTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCNGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCNTTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTNAGCTGTCTTGGTTTGCCCAAAG
+
)('$!$$$!$)+)"&)(!+*)'$*)!%*'"""#)+!%'*'+!"""$&"%*##*%#(&"$'""#''+#"()'"'#)+&)&$((!%+'$)+%(#'!"'!&%"+!(*%+%)!%")*'&)&+$#+(!'$#*'($+))$*%#%#%'&'%#$)%"*+"+#)"&&$+"$(**
@r6081
TGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCAT
+
,/BF4F5&26(=@8,/7?57/9@$E+2.F)>A@:158E8C&$>%(*%$DA)>H)'1C<;/<>,1*'"2.21DAH%1AC%9;8'0/:9F;>D%DG6;FG/:89;+(;B+1(=@-/&"4*4D>9)H#!A*:B*<,
@r6082
ATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCANTGCTTGTGAATATTGCGTTCATTAAATCG
+
4+7,1AA,510?C$$!,A=D?/"F<<H.1#*$%2@#3"',.!27C0:$&@+2A9H:6;4699*A$@50%G:''21&D8&,>EE$>$9"(085:'F;=?/A%0!.;BGF#,'#,!:02.>H4(
@r6083
ACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGNGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGTTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGNTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGNTTTCAGTGNATTTCGGATAACAGAAAGGCTGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGC
+
(<BG9'6""@14-0-29"C#2F968>%C;"A*:8-)H6:,9!*+*;@080(4.3(:)18<3B4G>1#=#5&):ACA598-.AHD%,-EC0#.?"F$<8+E>&(84G5E-%'?5#8B#C#)F;-36:2=>&-;38-57,!8+@>7*0$>#=6C,(D4*AA'46A@!0C&/HH83+>5A8!1%.<>F6D5<C%9@$=70B)'.BA;C=#D(C71+*)5G4;$&75=-1$.7&9G95A+0(/-4H;%8)11,-&?<4!D75(A$8A'+8,F8*C?%3.32>D"2>(@F%9!CGBB?84@4D=0<-+BFD%==3,B1:/1!<(71<.>%;H#22B'041$-*?:6$!406A,BB;&6B>HA'/<?=GE#E<=D0E:BG@H5:94?#*5&)09((6@H:H1:72*+?"=23->=>)=2A;!DF#C,):,79=EBBF7;G4DCEC),F,$H=84%5.81;<F::$8(-8$,4:>F$;<CA<%
@r6084
NNAGCCNTGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGA
+
*"%"*#"+#%#(((#')+$"()$#+*#**(&')&((#"%))#'!!#)$*)#%*$&++''
@r6085
TTNGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTG
+
H3A4C:53=%(A.F8.!'+/:?53"/57A/2/BG9*41'?"AF))#>
@r6086
GGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATC
+
=>F.,,6$HEC",3E0<>*C.53>-(&/E3("!FB9#'+=4&G@&;+4%1H,H/,>!#&%H(+?+3(
@r6087
CTGGCGAAGAGTGGTGATCAGTTCCNGTGGGTCGACAGAATC
+
."/('F;D#-B-715A)D8()F!F';9,/:F$='0;C':=+)
@r6088
ACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGANTACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATC
+
.4.(G3/-GE-(:49D7/>.8D6127.$-(;B(981E-';:'CC=4$(=>@+7@>(?+>)A:-#G3-?='#"F>-!'8/+HD"+<DH@09E!-$G=2?/':&#0:*5'0)?%"B*-6H*G%/$7;.,"E5H&5!C=;%)@0-?)H1F58GD*&B."
@r6089
AAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCANCGGTTTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCCACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGNATCGCCCTGCTGCCCCCAAGCATTTACCTCCCGGACTGTCAGCCTGTAGTTCCC
+
,F%C!6:.":@.2BDCH=@G@,$'=75A*,;">.H3&72C#E1:=&:4;;%0G!@/90?"F$3):8D!2:)'/:#;?><&A>58&:-43@-#C$C2F*H@@E%90@+!+:1#A94D1E@(*D<$EF%;CG:@'#(2+6;A8A3=)()<1:2<A)>G1;6G.,?=0F(86*GB2+%E%<BD+2E&H.:?50<,(7$42F2*53F"EA->D%7*1A((!:FF#@$"B>4%<.@C3*=A9!76*G9G0$9"@#+(&*6D74)=45D&06G./E-&>0A+-<.>.8(H&=@18#3!BG((CD<@"$.083%#@-))G@A!+17B978'-*/A*#;6D(9!!BBA,6C*D+5DF*3@'C=?'9;&G(4*F"!:;?9*<"*)(H'(0>@&,G&5;G3G2?1'G)=
@r6090
CAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGGCATGCATTGCATGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCA
+
'+%##!#*)%#'%)"+"+**+&&*(*&)+#$!#!(#$&&((&)+#+%)!))$%&(""#'#$+%*(&&'&)*)"%$(&$$&#))!*&$#*(#)*&)&(%()*!+&+)(+"+*$"
@r6091
NCACGCCCGGCGACGTGCGCCAGCGGAGTCGTNCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCC
+
*%+?,#;(H#@-H,:@<7+$'1D31)!'6G6FD-6)1G4G<(=.#%@4(,;/&HC&5?='+5,/-<+:<?3"(H(A*-2='$->3!$&)G!@E@0,"-:&8#;+-,H<8?F:
@r6092
ATCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAAGTGCTAGCGAAAATGCAGGNGCAAAGANGA
+
"3A6='9!$)0>83G3&(.4.D<*DH8#G":%"7H5@C=9)D:%=5G(6;G+<1B.=>4/0+3$=E%(HEE&3"E>(=7//+?33-GA#&BD110@4'@*((-H5!G01.9)>DH-:(B10?*"(/BA1(/C1+G*-/>9<A>F*D10+')C:"F9/'%=",*7@/!C->E'F7/9B)<8B"?2EC+#H?
@r6093
AACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATT
+
B/&#E#)D@#CE.'1"5?*6(=D"(@2>&0@CA/!43"--+6;D6,#2#"/%DE??;57'EC+;F$F*##2:FE1-2<6:2H)4"2$!%H#&.&6H<,H-E02=8<+=DB/<+G%*7!
@r6094
TGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAA
+
-1;?&>"#(&-0G451'$,BC:E%'2"AGB,*E3+-878);'14"
@r6095
GGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGNCCTNTCCGGCAATCAGGCGGGACTNAC
+
08F4FE/F5=07"*!:5(:B(CDB1H;"E+?8@:0/9-FD87:'::G:&)9<"0(>G6.@A(,1G8.(H9:,A/:*)5(3&5!$A@@-+GA+=?:8F.8;(-
@r6096
CAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGANAATCAGCCCGCAGCGCCGGGATTTGTGG
+
6;!-/;1=0.2<?(H)5/C:2'3.F3$7,G$=F:),195#@%=%7G=1G,32;>&B"E<B4F8BA/,H6"8
@r6097
GCTAGAGTTAAAGNGCGTCNGNNAANGCNANCTCNNGCNNNNAGNNNNNNGNNACNGNACGNGN
+
"$##$#"#$$$$$!"$##"#$!!"#!"#$#!$!$!"$#$!#!"$""!"##!"!!$#"!$""$"#
@r6098
NTNAGGCGCTCCGTTCCGCTGNTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTCCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTNATGA
+
"'!'#+')!&##'%)&'$(')+$%%''+&'(!$%(%!'#$(%$(!(!&()#)''*!((!%)*%&(!($')*!%$&))*''(++$")(")*$"%'%#&#()#)#++&#&#!*$%'%(''))$
@r6099
TCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCA
+
C(7$>,,-92%.2@@B)=>5@83CF)F@#%D@)=/*072%
@r6100
GGGAGAAATGGTAGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCNGTTCCATNGNGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGC
+
?:>@AC8(66"D=32><;$4".:##48713C&36+:996223$4?-,#3"'-<!&>F#>7.!'2/<3?'CG5@>3A-658E8,&8/?9&=EA7GA<:H-D"G/4;575:0<A3-+B+32*4:)3GC0/%$F#:@05E3*<35
@r6101
GTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGA
+
$4CC69-.>.)H7C8+'F2<$H/:>9B/?)%";/"/!3$C#,?A!B-'
@r6102
CGTGCTGCCGGTGTCCGGCACTCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCT
+
<!24-<H))-10BG?818=$%4GD0,F1!C9=2307?0B&E/E<(F9DB+4G#*?2!D=)/,,"F-%7C9D<>8.H0HC2-'C-#1$!5$E(@
@r6103
TNGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACG
+
#"?5'&+@.<=<.5+G">7=35#(7>!9)3E..7*$1AA#(DA'-),=DH.1$6-"&A-C(946,02="A1%$9=6%"!@</7?
@r6104
NGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACGGCGATTATCTCCGCTCTGGTTATCTGC
+
*=H$H'+>"9)G'?GD0A;"4!:/*$?38'<0426F:F0@"&9C1(GE>.F*(4-2;DF+D>,"3:B/,C;&B04@"#F=EH@*1E/>--H466DA>()4;9>#%>7=>;A09-9@DF1407(6>!?=/;#=),F7C)446"*71>DF:B)B'4/$H$D@3F!$@4=3E<HBC##9:-B"$3$"$183#*867"5=D5F4HAHD.0%<%"AE4&.+DD/E950$>0G,?!?'9+(@>&1GBG=?!33*>A(&6@:*'65C+/+GG6>?2.,D8=#"*(425BD6CC65:H4;2<4&5)'))*-<4A!()BE#%EGA,D@;7:.
@r6105
ATGNNGCANGGNANCTANNNTNCNTCCNCAGGTNNNNATTANTTNNCTCTTTGCCCGTCATACAC
+
!!("%%$(""(#%$)((!!###'&&)*!)&)*"#&#'*%)#$&(%'+'&'('%)'&"&'"*+##(
@r6106
CCGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGT
+
/H949->:$A8E(C+9?6A&6)B;=C,?+3'>#?C'B#,E/C/E7E"&F->#C+H+A$=?3H(*#>#29(A619D/CB='>C(7,D=&FB&-<!-17=:.G)81(?/@.<B4C7%A)E;(F:86(8?G186/(
@r6107
GTGCGCCAGAATCGCTGATTCTGTCTGTNTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAANCCGCCAA
+
F0'&7C<F(H;;0B*H<($,.<DHH.C$:74F30B9?21.F-)$.@)!%G9"1<'F%A14(4"G956;<8?*B6+H
@r6108
GATTACTCCGATCACCCTCGCAAACTTGTCACGNTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGC
+
/$?"H.+B5C7<?8:026#7!;7C*D5.:&</1!H0C>>BH8/!8,A0?>354-)AF(?#BE7>82=@G39*!D(2:1'B*5/B?A12GF#44%:,F:E:68%!:76<40"%;0:?"=E9+8?7!30@&B6A"F(27BC12D+C4B:D61&77H7@9DECD!@)5E-D%-*E(+2B1(E@%)
@r6109
NCGCCCGGTACATGGCGAAGCCCTTCTGCGCAGACGCTGAAATCCACGGTCTGCGTTTC
+
#@E&#:>$6:E79&-D(:;-6%-&;FE#H32AB+65(;4H&!$&;?&#A>6F/6@!A0#
@r6110
CAGCNACGAGGTTTCTTCCTTCGTTGCAATTTCCGGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGC
+
3-%#(H"<?(DB+*;3&)#414*$;/8"!-(9.HB>1)'D&2<F9;"4*99-!F1.#8G%?E)!7E@#:#G+54H
@r6111
GAAGTGGAGGCCTCTNACGCTTTCGTGGCCGCGGTGGAGG
+
F*'(*(AB&/25&7A:8E?3)5G>5#&A!<9HFD89;<"@
@r6112
GCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGA
+
521;0,0HH7<,$==2F!:6AH>,7@5678;D,C6%/G/44)HE.G@)??%,'6;%4$HC5;E8A7>D6EH1=;/CA+:@-E.11A<
@r6113
ATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGCCTCAA
+
,(H0F6&)2<8")#8G4.*.8!>:#8C5=H7:AF*<0)&.H
@r6114
TCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACCTTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACAGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGG
+
4B96@B-4/H27A!H8D.0H13F%'8<+6=@#5+84%85F<?,-C)(!#..=-HA;H'A>)/>6E2&8&%5??%A90#71@#28))',E@,1@"9%1?"#9E$C54+FDCD;81&:+)4?1@2,B,&EC3A>%%1E49=
@r6115
ATGAGCGAGGAGCGGAAGTTAACANTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCT
+
*,%@7>;@*4#+,<>17B)?&&'+H@>3:984>$G;A&%+!1!*C'6$0D;02&7'4.98)9:++2
@r6116
AGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGC
+
1-15H:)7",4$*@F!+141@H4E=F)'5A=94<CCHG/)'D4=#<$,/@$1F&D,H+=6%-&.!;D<:F>A,F
@r6117
AGAGGGATCTAGAATATGATTAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATA
+
6.9#!*&)8@B.+2+EH"8"@=#C*+/?+:8;5@;*1,E0<.EG7G:>'':%9%F;9;@,GD
@r6118
GGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAA
+
D&E)75';:H755F)><3.G9$$3#+?-G/DCF'$&-(0:C1A/B%@
@r6119
GAGGTTGTATGGAACAACGCATAACCCTGAAAGATTTTGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATA
+
-F,6G@(&'@.-?5A.FF!$2BG)H0CE.76)-&H#7$7C*+'C.7$'4'G8"64D/#->>58<(0&5'@'D!0=)"'5,5/#0<
@r6120
CGGGAAAGGAATGTCATTAAGCAGTGGAGANCGCGTTCAGAT
+
G264;:;7%,3%48E33,C&3B%=(DD-=%0.A%6E/&76EE
@r6121
TGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATNAGGGATAGCGGTCAGGTGTTTTTACA
+
(/&9@6@;0>*(4!BB.%=.'?.)E?773"/AG:)-7;$@:+F9*)5+!?7$@$1;?5)FH8?(:F16H@#D4-/%!00A(!%'AD>1H+.+(5&:@CG2."1=8#>==4A84;*H7E:#1
@r6122
GCTGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGANCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGT
+
G4C$(:B*%3+*;4"8''(&A"(4?(C--$3E@HC!8:"/=5):&:2!D%F;.=*2B?'#$!%G+/'-G"&"F0:C=;8C!:#F0)H2$:=H*?@&$-;;-36"6D>"-H;7C%A??)F)/?&$ECA:?)!D5,+H@/872+0H+/+"(55+="3))'<@4#+
@r6123
ACGATTTGGTCGCCGCATCGACCTTCNTGTGAAAACGGGGGCTGAAGCCATCCGGGCANTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGA
+
DA6=*B&4?#$#4@!%A87C>983;:%;-H60@<.E<+;6#$3B4?4>*B>=49D)?%1,9@+"B4+78?=7@+7BH##G;?"(!-5*+<0,!EF
@r6124
CGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGA
+
A@G"B7A'5C8E>2F*"#/G)&#C?1-*H+=7-&5).=<582-5G9:@'3+C:90
@r6125
ACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGCCGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAA
+
79#44=1<15BF)5=3=7FE-6+:,@=))B+%-+'3<DC;)9EC&>3>79F9!0-3B=)8-&>BB5>G9?DA56GB9;)(0,%);:;3F(E%?+#F47D<!A8!A$<*1*B:@#2F+7-)6(.*+#$*..1!1.);"+5B5C:H'8D"D9
@r6126
TCTGACAGTGCCGGGATATCGCTCATNACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCANCTCCGCCTGCCAGGTATCGCTGTCCAGCGCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCNGCCTCATCAAAAACAGCGGGGCG
+
E5,1E;!-!8B4.ADE<-%!)4&&4@1)/'4F3B1(=%8!B'=,7@%?8H,03H>51,$7?,>-C7<9:/@.B&82*-4&B9D9(>4(H!/EB<3-B6)1$3;H2G!->(-9?3(73!%H'4$02-+,4F&G5$H@<>:=$4:%1$=.:9'.)"9A-FF*7;3F?,&33#91'"9*.A+<"4F-D>%&E>9!4+6$$+HH#306@62#/-B0
@r6127
AAACGCCCGTTCCCGGACGACCCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAA
+
>A=!H32B68;)CB/&+&/B!0,7D$.+'&=G!$"'?801.2D#8=E7H?E$F0B(%4'#%7&<70"$-*E/,D58<FE49/;C/,@@C8E%$*F%C(
@r6128
ATGACTACGACTATTGATAAAAATCAATNGTGTTGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGATATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAAT
+
.EBC,1'8/;C;11)=@:$-0,G<12E#2@9'),H#2?8)/?&A0.0//B1/?;=.'!9(.#6D0@'53'E&"?/B'E8"C(;A3H'&86@H<8/.?85.>38=:%?:(97%F8=<D&;0<+">?+G@(>A.!''/HA>*>/B
@r6129
NTNACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCGGGCCCGGCTCTGGACAGGACCAGCATACGATCTGCC
+
)*'+!+%)#$'!$#&!""$"%#"##*)%%"!&#)"(!(+*+)"$#*&"(%)"%'#+#+(%++)%&&"$*!&#!%"++((*+)+%%#('$&
@r6130
CAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGG
+
9.6$DF#?*1#C*0(#)D7.;;0!0%D&2)3@0C-.7DD90)<8,21D-D,@+7B2.+',$C@32HE&5HB6#77;4
@r6131
ACATTGCTGATAACGTTTAGCTGAAACGACATACATGGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCA
+
D79B:.0F3@&,+!#!"D.:*5CA:7$1G?.66D@;"4!+%1315!9*2=?B@#/7?H)EA+955@#>:-%-9&7*4/A6(
@r6132
NNCTNNNCCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGNATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCNAAGTTCTCACCGAATGTCTCAATATCCGGACNGATAATATTTATTGCTTCTCTTG
+
'"$*&$"+)&!*%!%""*&$)'!$+)&!!$&*)"+'#&$"#$!+"$#$$'!!$&$)+(('*+++%()'&''+"$)$)"#$)'+)%')""+*$((!"+)*+%"%!)$"(!$%#'#!#*"$%'&+&+('+"'%$+*+""'"&"*+*&&+(("+$"(($)#)'$$"*'!*+$**+*'$#+(%"')**#(")#&!"'"&+*$&)"'%*%'%)&!*$$'('('+()("")!*""&'*'"""!+(+&&
@r6133
CTGTTCAATATCATCATCAATANCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTT
+
2-6G;73*H,"=E#B4,H,$+?5+@D89!$21G),GC?8/@8"*!C$7??B1!0&?DAD/3CH?GC;-+=6A-##<C6%/7<G
@r6134
ACTCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGNGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAA
+
&)%+)(((!&&##)($'%'%$$'##$%$$'%+#**(*""&!($(!!%&+$!)!*+"&+$#%#(*%)++('#(&$$+&#*+%$)$#$&(!*!#+&**'#!$&!"%(#$'+*((*"!"%)%%*")%*%'%"($(')("!)(+!
@r6135
GNNGGAACNTNCANNCTACNCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGT
+
*&##!#"'$%#*$)!'&&$)*)'+"'&($"((!$+!*)%#&$%&"&)(++)&*#'($#'%$(#"("&)'%$(%!('#*"$(#%#+$&+*!#)%
@r6136
GTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGNTATTGNACAGAAT
+
>(*.%:=??793F)"*-<E&,/55@(.0GC69@B,2+60-*!1CDB98,:@%%=9)4.G<24'76@63#G6;:C.$8C:3#)734F!=>/+H5.
@r6137
CNTGNTAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAANTTCAGGAAGCGGNGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAANGCGGTGACGACTATCAGGAA
+
*!&*!+"*&)(#$))#)*)%+"#&)+'&#!%)%$*'*!$#"))+$$&"'+#"$)&'%)&%')')+'"(+%#&)")('($!#+%$$*+*&!+*%'($)&%$&#")#)+%)+))&+"+&%!)+"*!"(%
@r6138
GGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCAC
+
C)=;G/!$"H!>5@/=--"%H?H>?;6,5A#6$@<'%2-E;E3D5.01&1
@r6139
GNCNGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTG
+
#$(()(*(+('$"(*!#)"**($%&&()+$%#!&('*#+!!))*
@r6140
TAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAA
+
7@.F%.'DE*C5GA<=$8%:G0>&;9<-$05-(54*=H3:%$7=5<+$2<(A*
@r6141
CCGAGGGACGTGTGTAATGTCCNCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTNAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATG
+
+$'"$))+)%")&"+++&)*''#)+('(#"$!"$++"($*!%$)%(%%"%!+$!(!+(&%)*$+&%#*"#+'$&)(!*(#!&+"&")%"$($"'+%(#&'##$)%"&$)+"+!*$!(&+*###$+#$&!#&&#$%"'#%($"&%!'!"!#%%*&"(%"**!+('#*%'"&+%$*#%!"&!"!%(""('('!"!$%#%'#)%#+$+$))#**+)%'!*'#$'#"'*
@r6142
CGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTNAAAATCCCGATGGCGGTGCCGTTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGC
+
H6'B$4@'6H+:*G@2025=::D#,(<*(4#AC#3'=H"6+4D>.3"&$):,G?H72C@?,,3=88;6$H5G%&+*98?E=((BB:)3.A2/C->4@4,/240<>)C7748-9)D<7B:<601/D'$'DF%E.*F,.,/9B60*@)%A>@%1,,,C>516=1E54"*+;@<:BE*B.19=4$'>#?%<4/%3F2GA,=)94.9B!0$;G-53D;&2*A=G?&152,<))%*).:HB2$H:,<'1$09GF.)+94BF%D'0$G''B.4>B+F32&AD$:(3#,G(<C/FH<7E'6''-*F!.#/84@;8'H&-3<7(5F:)5A6D&139A8*$00,?"4G
@r6143
GACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTG
+
;<-5%<*.?G>1:D)E*+C6>=,9G8<@>2<9C;:($<79=F?9$8/;-@5,@#DD>3B.H-(5%"4B2-1"E%'8%":-62>F0@.-$3/,1/2$='&-05*E>G'8$%3E-5?BC0#"*?/0@<B.D.':??DB,BH1>E8,08G,E9$A-6-3!/0&=,2&&%17*H:F02/'H5D#$<+=-63,9,E@,9&?B1!2!3H*?,$EE#5"-&'"7;>:')E-)B:CA2B/6E<E#85);F;A,@>!AE97H33)!4*!
@r6144
NTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTNTCATTTGTTTTGGTAAAGAGAAAAGTTTTTC
+
7+*%&.&5<1%*1C*7*(6##F/6-A4E5?@F5:,<;/%1.D,"F./.2@:0*=FCA<3AE$E52+''9.H@#<36)9105:G,<#+6"
@r6145
TTAATAAATATTAAGANTATGAAATTTCAACNCATTGTTTAGGGTTTGTTTAATTTTCTACTCATACGNTTCTGCGAACTNCAAAAAGCATCGGGAATAACACCATGAAAAAANTGCTAC
+
47@0/10#<>0=;'<)5&,C#@7C3@%B&GEGD42@%4:!G"H21'00.%?HH'(:*!"&#"-H$>+=0,'G@DB612:4*5E'A2!3C;?B'"7@@D51#A9,F8$?4CH5)A+:/4;D
@r6146
CGAAAACCCCNCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTACGTTTCGTATCAC
+
<&(00@2&8)<.2&0=F/9-5%'!C?70&&7"$%'#*@A?$-C:D*'A3>,=1+H*)?%?+?2##GA<<76<G4E%
@r6147
GCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCCCGGTCTGCGCTTCCAGCAGTTCT
+
6=<-@%(,94+:D/?-/*<>8'%B%*B:69?D-)%%>+$F;$(=.BEE9=#!D,F5)&%%$9>0#;60#.F%+/"&4;,#68?(5
@r6148
ATACTTTTTATATGAGGAGGGCTGTTTTTACCAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTANT
+
+#$*!(*!"$%%#+$("+*)%#+&'+%($$'+#*(!)"(&+()%(''!&*#'+(+'$)()$'$#%$'(&&'"+(")!(%'#$'&"&*#$#*'()(#*%+(!!!!*!!'!$
@r6149
TGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATC
+
25-3!F5C4&(AC'#*4;E-:C/-*84<1%><&F%F@):**G>(6?4)@?H)/A*3D8?/":
@r6150
TCACGTCCGGCTGCNCCGCGCTGGCGTTCTCGCCCTCCGNCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCAT
+
=&2-FH?"C&HC;H76G;..G*D<%(D,>"=>"A+/,%>)-4/5(3B"'A)=D70$493):4F3*#13%41=7+469?**:H)>5-%B:;=3$D-%A>G.7/$&84<5+'CF:7;
@r6151
GGAGGTGGACGATGAAGAACTTCCGCTGGAAAGTGAAACCCGGTNTGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTG
+
D;7&HD?';)*.ADHA;$/"95-/)9-")=&/>/%53"3FD%@E<@,F8C5=A3.6<HD50;23;#@-77:C&D'7)C"C<?=9GA/&A&C6/1H?24#526C#-<3#.,(68,
@r6152
AAGGCTGACCGGCTGGATTGGTAAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCT
+
.8,0H9%$:7&%358=;)5?E2#."=45;;%->6E85F@*3)3/B5;=,+&@?8%/.-7.:256"(1%?D?43$"./$H-*.C6+9H*2(5@"&H$(AB:B2?6<;A""?51<%3!84
@r6153
AACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTA
+
%=<9-C4"$/*?408-5*2%2.?+&-,'41@A%%6'>>=:,'6/6:<F&='(
@r6154
GNGGGNANACAAGCNNCNCATCGGTGAGGAAAATTTCTGGGTAGATCGGG
+
&%(!%%)"#&#!&"#%*+$#++$$!+'#+*!'#*$"%#("!*'&#%'!$#
@r6155
CAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGNCNG
+
@'3&$/0))BC*/(375;6C9<51A7-/B=8-F=H68.*<&:3
@r6156
CAAANTGTTGTCTGCGANTGACTCTTCTTTGTGGCATNGCACCACCAGANCGTCATACAGCGGCTTAACAGNGCGTGACCAGGTGGGTTGGGTAAGGTTTGGNATTAGCATCGTCCCAGCGCGATAT
+
+%#&%%''!"")$)(*(&"*#*$%"*%*)('!%'+!**#)&$%()"*"!**(""%$)&+#*+&($$&&)$%#("+)#"+"!")+()&&*(#+"!*#&%#&)+#"$%%('"&)$*%+'(%+&"#"!&*
@r6157
CTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGNCGATGCTAATCCCAAAC
+
ED2=D&?;9-/"/=8502;&G;932##B-=E?'5=.D:#-+=B'0?!;H42G'#5H,8
@r6158
AAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTAC
+
4@3,C474,&<2/>.@6-+4.%BE.$41%@B7,A-7B?C983@!&1,1%,G5C1@<C?0+C+.3GF;68:)728DC;FH&3*"G*"%HB"/F@;C2.HAH(4>.(F6-@98>;446
@r6159
CAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGANTGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATA
+
G)CG2,AAF'3B50376@D2-2$(45;&:B=(,9C<BG(4E(@&65"'9=#;)+21%%<7$GF$$.&1"=2#':.AA4H9+6&H#8@A;/>9E(=D%#7D*%;&,'>8&1%G.HFH-<<?DBE>,$D!,EBA=)GH;62F/:-;B)&<;+7<57>D4FF
@r6160
GTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCNGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTG
+
."&:<(5%006:!H55,H$0&1B#DB)E'.G.;FC*2:$DH4<B5">)/@(D5A+HC9"/F-F-=&97>&;;@=#HB?>>E::A0A<5@A.E)#/2),/H5:#"?#BE'4/8.(!.AHEH-<9*7D6)>530C+;&74;G?/F>
@r6161
TGAGGANATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGACAAGGCCNAT
+
6>69092AH=F3!18%2:&F?4<+*74D4A0G=+*51CD"/'*==:9*'$2;A-2.B>,>A&,@E=C;+G4>
@r6162
CCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAG
+
3!=>#)D+F@>DD<7H%)171'!A7)$77794$:0H&.!(
@r6163
GGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCT
+
<?8,,?,/>GE+D?9/?7;3C81D9);E;A!.568!;10)F26!<E>G%=
@r6164
GACNGACAGTTCNGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCNGTTTTCAGGAACATCGCTGACTCTNCGGATTAACTGGCGGTGACGGTAATTTCTGNAACCGCAGCNAACTCACCATTACC
+
(#%"+&'$++*+*&!*&(!!##+%!)&#'"''#")($%+!))$'"!"'(###!&%)**$&#$!%*"$"+)&)"$(#'&++*)+'"(#')$#"")#!(%%%"(*)!'"%)"#$)'#!*$$)%!!%'+&&#+&(
@r6165
CACAGGTTACGCAGNACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCA
+
#*1G=,8H".<1H=D9:5DF5#0!3E.7)HDA70))0?)D1-B!-FC;8=B.);,>20.=4**.1B24''>?-:A;%#<"'6E/&;.F<C%E02F<G$(:!A."
@r6166
GCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCTGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCAC
+
7DC8>H73AC>?-?1G9.BD92!<5-,)&G%E9&)>@9'?6&%+@7HF5A%'C81!CF;&177BH0)+2D9H!:+*".;57A=10(7,">;!%0&<82@--#*!0(;4%</%.E48C:>AB!';5.8.C'+*?0%@9;<7;-@F#&E#68H:E
@r6167
ACGCAGCTCACTTCTTTTCTTTCAGGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGANCGGAAGTTAACACTTATGAAAAATGGCTACTAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAA
+
B(7FG/?A#F$144B4+91%E,-$@B7?==3##"G@./0:.)-63(936@6D?*0$D(A8G&!A%96979:9*D.=88,"E+8,A&7F)CE<5-'67/"/975'4'8.A$:%0#*A-</2<#2#/8-9D"&,()-D,?)(CE%54E,8(!C#=>7/A(!'E,/D5;*E"()4+4F9.40)E8>
@r6168
AACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAA
+
859D?9@72>6B'C-4?B73%$%;;2G7?=183<(=$?8.$"96F<@7!'!)C?483(;;+#,+.1<=E"@6%G4#,+HCH'&%>,!+.)1;+$,HC?326
@r6169
NTCATTGGATGTTCACAACCTGTATCCATGAAAACGTNATG
+
#;DE9'20HH!3,<<B!.+A25-?"6B<)'74!?("%2:0@
@r6170
GATGCTGGTGCGCACCAATACCAANTGTATGCGCATGTGCACNGGCACTCACGGCTGTACCGGACAATGAGTGACTAT
+
2"5%+4E+228A/+2!8?)C((:472GHG@,=6GECFD.AD%G+&'9F1(:#,-4*:3,*6H>EA?D<506D:F)A"@
@r6171
CGGCCGCGACCTGNGCAGCTGATGCACTGGCATCGCCGGCTGATTTCT
+
/')(7/<#:-49'?H(%<+6@7=:''-F$:G!F%.736;%8985G&C>
@r6172
AGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTATGGTCATCAANCCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCC
+
1<,:/7A,37B,A8(E46@12)16#/3#>E$>%)44-2'"E$;,6*<'A:86CDA*E@D*167?#;&'-;'0,.1FE01'2-4B!@H"(78@B<+$F/.C++?'C
@r6173
CTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCG
+
+""%)%%$!)%+(%)&)"))+(((''"$(!!##)*$'""%+'%!(+%
@r6174
TAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAA
+
8H231!)7<0#(706<8?!(:%<@/<'A%&'?06.E>$F)//5%@!3:C+B,,"B&3.H=/-G+(9
@r6175
GCAGTNTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACT
+
+(*'!'%##$+"#+#""!&$!+)#&("*#'**)!(+'&+())#!*))+%"+&)"')(+++%)"$!%&#$+$$#*!*(#&%(%!'"%""%$%$+&$#!)!&#''"+!*+$$&*#&!+((('%"(('+&
@r6176
ATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGG
+
4*4F6F#5.!6"":2,F$"$8?B3<<3;G"0F#B.D92G9FB=/4=;=1-?G.GD<+4@7?76)(,A#+/,#?@@(*6;44-!/;#F1
@r6177
TGGAGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTANCAGCGGAC
+
74C<A4*@@8>D:5152(:-/("$1@A$3+$@42E.$?-:EG1<,E3
@r6178
GAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATAT
+
4A3-$)'6>&)2<F<8'8;!>&%:EDD'G(&)9'!488*):?-BE(G;9#&7>&;,3-0);F3',F<,>'A0@;G73+2
@r6179
AAGGANNACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCA
+
(#()#$!%*))+!))"&('))('%!+&)'#$$!%$!('"("&)*$$#("*$*#"'")
@r6180
TGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTNTCAGCGATCCGGATATGCATCCG
+
12;"+*%C96E7@@@*BFE('!=%''%>":$D;!$D?"78,/4H$&#<5$5FAE2-;%)&D/&?1#-4!+
@r6181
CCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGC
+
7(D#79+""%A9EBAD1'+!;$'CA>#CE)%(+D#!</68"(,;A#1GF0DF+9ED<E
@r6182
ANTNNNTNANGTNAGNCACAGAAGTCGCCGTAAACCCCACCC
+
(#''"'*$)*)#"(*%(''!#%*$("+)&#$#"&$))"%!'(
@r6183
NCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGNGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTC
+
!,>078D@.28!"0%3..,'57?F6.9='C/$/>E@90!B*7@%+G?#!HC20%!0(!+6FCD$%/&&>1.29E@F*/<#=/<H#18&$;-9%0,GC-5)*#H99*2CF=#7>+=E2H090;$:9.
@r6184
AAGAGNTTCGNNCTGNTGCTNGGGCAGGCCTTTNTCCATGTC
+
!)"$(!&))!!"%$)&%('(!+!&$*+(+!%!$((""*)#('
@r6185
AATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGA
+
>5%%)&@B3;?!:B'2A9,&=35."%'1$,<5G'7F05B&1FC@G<*:H-3G)48:="70+3.E9).#8DEH..6C&6E(*2C25G.!=-03=%D9EHEB))?#%"0#
@r6186
CTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAATCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCT
+
+(#'&&#'#$'+"+"+)$"%+))*&(%()*'!*$"'*#"%%'(!#!(%%"+)&&('"%$'&)#(%*(!*&'%#+'(!#$%'##&*#*(&)%*+*%"&$""'%)*%"*!"!%#*#(#$!)+("$$)&(*#(!#"*)+'$$(&)'$!*%(&*+''(+%"
@r6187
TAAAGGAAANACNACCTGCCAGTATCTGNCNTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAAT
+
*&""('#)(!#("**'%%%'(+#&%'!!'+!*#&'!+'&#''*!$)%"%'"(&'+*+##))")*#%(%!+
@r6188
GAAAAGCATCAGGTCTTTCNTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGC
+
$+)28F$@/"-%%@G-7+?@'>0)!%.<<-CB",9+=?$10,")69)6(4;6*1C@$C1E$7B4<;#*E69/-+,".1)$422@(+!E+!D)C(.,*6#:'87%#(4GC+:?,*'(3-!H
@r6189
TTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAA
+
8A(;1#E%*47A<10"H>+(D96&;!&=!C7?+HA5BCG4!.>++15765%@-!99B9AF#)(*,@/0-!78E565@<-
@r6190
GGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGNGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATT
+
=#3F#+>7(=8*.2#5$)9>7@#/)?.?!#H)3G5)(5!73./"*)H,1B:3C2+(.9/D):<.E0H%H.FA'C*@H5%77+$49"G%:>0/9'%D9C$%19),#?H7A*'@<D
@r6191
GCACCGCTGTCATTAATCTGCACACCGGNACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTACCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAATCTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACNGGCTTCTTCCTCCCCGATGCCCAG
+
*$<$)E6!!D2H!D$:54;E!65<.E2C(6<.C84F:)0!D;.:$E(?67..!;#:3A3(FA#/.0G4B3&=4G*2.)(6(46$5HE@E$$?=!!CB",H!B:&<@A'9',G'0+38.3!.9G,)4.G"%$0A<?1H'%6#"-:=!3!6/,"@@&+5G"6H@G47.A;#G;5*57,F?(&+/3(*@5F1A/6D"58;0DHF&!="'6F3E@0+*D0'1H=E.%=80@H;-.*.EH*@"A07+3=+9(&+,4"%0;9H&%>+.'>>721!)%7"!C52)3E0>E<!-CAE335!%0"8F5)808%3""9(&>
@r6192
TGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACA
+
,:*"'#;E#E113*1D2.2'*/60116G()/70>E1F2-F
@r6193
CTGTGCTGNCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCACGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTCCNACAATCAACAGAGGAGGAGAAGAGTGA
+
>=(EG"-6"C>70-BG<6E-0677*13=*$23G2@FG"1F44H($#3A2E:8?C+H!H36(&1?38F@E+:C>;%&76E;140?*A%-3(*DF/A%,9H>+B"4;=3F>=>'-B$-.A*D><79*B:&41.A+&=4,A5&67*+5GEH'"B202&/*+08='F;F3>7#C"*3C><A),?4!C#8(-9)9/.9-)#1AHA.B,%B?C,'<08;F!*G>24%331<2%=F@(7."F-5)&$/9)B5!"-B1D9#@1?'76:'>A?/CE;:D<A>5'-;:-$1'88C*,'/G@H'?*;,2'?7,**8'D0F2?E!B.;$B?;A=50B(A78?';B"H$F0F,*'$@6/1<13
@r6194
TAATTCTTCTATTTCTGATTCAGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGT
+
,8C+4/@,F;$?%BC?@F0&.'F6/;+8?C*:=CH+3;/9)@CHDAA6("+&%2<H@)FHH!=)
@r6195
AGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATANTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAATCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTC
+
8!#>B2'1"'6D(14=:8F-3)!%)&;(!3':="1:FHA>$B-2?(;.E:E5)'@((&*#H@;);"*H/1->+<!0G,%2(DFH*-E/9'+DB?:&-+CHH*+(8#CC'25*B#:$;A6'"!/9)0)0?5-;E*5H!'C?/+.G%#:)87:8?:F"(A>A2=
@r6196
TCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAA
+
,#=1/?%-G*C.</BF3(#4?@/>/6?8AC01?#H>,:66EF%H>)62(,3B1!+1;D#643#68;)AB4
@r6197
ATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGCCATAACCNTCCGCGGAANACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTTTCATGCTG
+
5$5((:/#)*C=&*(B6(?F%C))>,/(49<=;##EE3<4#GF6G*!E+E&GDDH)@4/8E0'?+B/@*,.>;GFAE751D6CD>+?B$H?):?@1C=;,4BB''6@'6F(->4=+8,G6D;D@G#F9956?#>H*2FE<7"$$.@G*
@r6198
AATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGT
+
+++'$%$"!&')#'*%)''*!'"#'+")(#+%#!+!*)#"!*$)$!&
@r6199
AAACGGGAATGAAACGCCGATGTTTGTGGCGCAGTGCAACCAGATATT
+
14G)17-B'-2@<3F&&E'<4B3*G<2@A)0@#$9;G%81H:CH0),+
@r6200
GACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTT
+
2!!*$%":99'(B6)&C!32-4B*:"<9<4*0"F#41")EH".?,?>2=.-%5$#38"!B/'B<#36<(<8*A>&',-%;.$2"C3)6'&-3$/?%.!+4)D4/9HAG'
@r6201
GGCCGNNATCCAAGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGNTTTCACGAAG
+
'($*'"!*)'))!*+(+'%)(%&*%(#("$'*(!)"'&#(**%)+!#+$%&%(($)"#$!(%&$&%*+
@r6202
CAGACCATCNATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGA
+
'A).)4E0A8"3=,4@-@)!4>59'';C".(4%48?)GC-#+!;9=2.7D7?98?-;5;+&('#7C:*<D
@r6203
GCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACACATTC
+
@54C?EH;9(00?%D%C/7,0(5):4;G?@!H&;@@@49CB0,!<--(21(6%->$:%3(C,<"+C,,/)E(*/#<!-?9B/43HF37'$"E-H12,@C%
@r6204
NNNNGCAANCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTATTGGCTGGT
+
""$"$"%*"#(+'%'#)+#*!'*"&$$#("#+'!#($)'(!+#*$#$)'&''+%'&)"(!'!($&&)(!)%
@r6205
CGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGAT
+
C@-4.1*C*:*8D&'5),?<A<5&9B.;8,9-'4>>5;5=D5+F:!!7&EH*302>A+;$'A'E14:<:E%9)9/,E,<
@r6206
TCTNCTCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAANTTCGATATGCAGCTCCCNCTGCCAGGTATCGCTGTCCAGCTCT
+
$'!(+##(+("&(+#&(*#""!*&+#%$%'(%$()!$#&*%(##&)*+%$*"('*%#)*)%#(&*&(")'$"'+(*""!%'#!$$&!"#
@r6207
TCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCT
+
75D'F?<2?6C1#!C3,F5":A274DBC27*,)(7&%)/D)4-A>?"-2:(F"8;D36/-*B%9
@r6208
TGGGTTTAGCGTGACAAGTTTGCGAAGGTGATCGGAGTAATCAGTAA
+
A=G0*6E+<"2%!=F54%=%'D;#H@E8F3E-<94,AA!3H43E)#1
@r6209
ACCTTANCCAACCCACCTGGTCACGCACTGTTAAGCCGCT
+
G3D/0@HH;&;5'?B=!85-!#3:$'82(7.=CC=,?-"0
@r6210
TCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCG
+
8:6.,41?*-"!8H!@:B(>)2!7$$6&>'3&8G>:-G4+@*6D&;%6=G;'-G<$),5?<B$&)8&0-:<63'!54>$30$9
@r6211
CNCNTANTTNGTGANNNCNNAGTATCGTCTGGAACTCCAACCATCGCAGGCA
+
)%$!#(')$""%#)#!!*!$%)#+&$*)"'()"+#"&#*#$"))*"&$+&&%
@r6212
AACTNCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATG
+
F334''')=47,'?@*A9%G-:%3:;=?/-=0;$+2<<E4"
@r6213
NAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAGAA
+
#BA-;F,6%5;(@')($G2!A>*AA*C+?!#20!9'E%-19+)H<2,)26%E;B2
@r6214
TAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGAC
+
"$A:%?E&**692/1#F#E6279+*,7%97',?B3:*)64/D-G
@r6215
GTGATGGAGCAGATGAAGATGCTNNACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTNAGCGATGGATTTTATTCTGGGCGCGNACAG
+
?9?)$@-#D:.3F%=5&-5C)81?02G&883,G*9*%B='%1&=1,C'"%+%D:)G7'.%)?+BB>,+H.+?@+6'/1*6=*B0!'5A(H1#%;!"G(>%?*3'5#F5>2E"E9F9B+C+C!>6=A"H.21-(4!#&6=B
@r6216
ATATTGAAGCAAATCTGAAACCTATTATGGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGANTTTTTCAGAGGGATCTAGAATATNATGAANGATNGAAAATTNCGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGT
+
!,A,0:?E)#=1&0$+%87/:%29%DF>;!37D@BGAAD53$$)9H"+F((/+.B(=<CC6H?(;2>+@"2!".1(*%?4=:(0604?>+/1'/+-G(@)(";+E3F26C.<'4,61;D:-<F>1E)4'..18=?E56+/'H=!"D94-0CDBB:2/+(::@"E?)G:@0766*<=0G9/#>;,<35)8<24/&54;*&*&
@r6217
AATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAG
+
9;-D?@'0!?/EG@-<!:G-.@/1G%2.5F"/12%%7'08'.(!C/%=:1!:@9C96:2!4!B6E@?9<C4C3/"-HEECCB.4<&9*<*:+%@6:*.5%/%"+#99<&+ED'3F<$48?/-C;)7':5)+3%5G6?=E:!D"9"F9,%9=D:98(=:D)&3""CF:'#7"3136+/'?E7GF48B#1'=%G/:(7#E2(E:E",=*-/#'GF:-FD1B-#%D6A.D+!$H1/H6H3B;+<20%!/@
@r6218
TGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGNTTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAANCGTAAAATGATATAAA
+
*&+'!&&%"'!#$)%#+$#(##'$+'##)+!$&+&#'+(+&&)*"#**(*+*!*&'!("*$#)!$""&)'(*"")#+&#%"'($!$+!&+#%(+'&&&!$"+!%"%''$#)"'$(*)%!"##&$!%'*('%"''*!"&!*&#("!!"!((+#$#'"'%&)('(*&&&"')(#"'
@r6219
TCNACTGCTTAATGNCATTACTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCA
+
**++''%"#&"+("##%'#+)')%+$"*($(#(*)'()(%$)%$(''"&+*#*''#"")("'+&'$))*$%+&(*!))+&")(#$
@r6220
CAGTGCCTGGTGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAG
+
G@.+@!7";G/3AD!C)A#?G2:.655"0$2DA(('A*7&;$<78",G7.=@-=6&5$)$C2
@r6221
CGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATC
+
9$>C/:9D#G1(15))E4%A90BG7,.B<(9</00&!%D/"/3G(F,+"*
@r6222
ANAGGATCNAATGCACTAAANGAAACTGAAACAAGCGATCGAA
+
*+:"-%@1*'54/3#D(F2#+=$,,=4*&:0AD1'A#H#4$*6
@r6223
GTACAGAACTGCACCATTCAGCTGAAAGCCAGANGTAACAGCACCACGGTGGTGGTGAACACGGTCGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTC
+
BA:(E)<.:5%>#G4?D()@+1G#50%;#<=AD?#G*")7H:(@9%<3$02A#7;F%-=:(5/4<941=&?$9,A%A@'*3+(<H-2?.3-09.1:2(G:C$01'8<.D4,E+&!6"F/6(
@r6224
TAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACANTCAGAATTTATTGAAGCAAAT
+
@@9<1>!/&E7($H6$,5D<";,0$D.*%DC"0E".$HD)FF!1"B<H'(D..-D<"?'!'$36D!<:/3$
@r6225
ATGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGNAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCG
+
"B<2:=7AC>!;(<><4:$"6<G2;;7:F>C55;<?26C=F9H'..G<??"''/,::0A;H$D1HHE.2%90:5!.6)>H!2&E2:E'$G1-"0)D?(<8)4?D9&2A#A")<,A'
@r6226
CCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTTTATGACGCTCTGGTGGTGNAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATT
+
&4"-%G@0#*>A,=9#.A04.9!H.E7,:"(,A$=&:;DB"$732.A-F+<:):<5!E-*+#4'B2C5%C-!84'0&"+=ED%B50:<44/9<4-$%.%8!H&$A8D(2@H,7C479"0HEDE.122B14
@r6227
TGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCG
+
'9'323.F<4-H%1"$!CD6*916$#1,$>A%HDB>H>):B1<?C6-<0C84'1*>?<F:8%-$296C6;
@r6228
CGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTA
+
2%859<50?HB6A+B!6/-(+G9?")E$DGE9A50:<2&<@D">A917./%9%F68$20?F7E9(6C4'0D3H4)8-,D2A<CHF#!?BCH>2=/:>9()4<*-//4(
@r6229
GCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAAGTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCA
+
"-8#H);/G011+61?5,9G(EF,0F),0E47?<D#*1)"5;G.((DDF'*ABG.C=:'?DH$AC@#%.#A/<&982#<"D*4,B;-99&!
@r6230
GGAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTT
+
(#+AA<E*.EE-$&'G<E8>)/<#72/=?G4?BGD$A";@6:$E>;9:-57$1:<?H#/!-3G55,+;?6,5'70;-B27,2,;/4(CG$%;GD*@52B
@r6231
AGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCG
+
*>(,E078@0;A2"%()FBH@;;A'=!1A@>1)77+D,H,A5@
@r6232
GGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTANTGAAAGAT
+
>5B7H!2/6D+:-):8).:?-1)%,6<!1=B:?6%;0)&.,!%8<C5;*9C1CB-#B$;0$><F71@E="",A6%/0D;:),"@*H*A(4&4FFF63H+!84AD##G=<)
@r6233
CCAAAGCGCATGGCATAANCTTTCAGGGTTATGCGTTGTTCGATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAG
+
4>@&('69!0@:,C6F*"+D6&>H292#;;:=>HC9($6A;)260%)6%(*'B80<0&3*"@1-3.4B!0?%.?C"@1B<$&4ED?=)7260(+0(/.;H':">+F8<E@6:((<?E(9""9EF:1.4FD0=!*E59075='743-8F3&*EB8/14*5
@r6234
CTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGGAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTNTTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACCAAACCAATTTTAACNTTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGG
+
(++%'#!(#((+$(**%"#!$))#+'!)*&#*)#)$&''&)&$!%%'+$'+$$%!$"#%&"'$)+#&$)%(!++'%'+'!$!)!$&!'$!)#&)(%!$(&&$$!()!$('##%+()*&$%$(("+%$%"$#)"*!$)#)#$)$#*#&&$''+$#""#%!''''&"+*")$&%'&$'"#%*+"++(*%%*+$!#(%(""!")'%('&"&$$#)*+!&"+&$*!'&&%"!%"*#$""&)*(%"%'*&)'&%')%"+$))
@r6235
AAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTNTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGC
+
H+H!:/G998(/,)FB>/1*=?&,.*)*:*D!!=&+65-<*+"")D5GB=E-7H0C.'$8!!=)F*@4"&997/?0(&<(G@5G@%'(@)1!G40%.&&E82D/%#HC&.!*.G#05,37->B>;&G-73*"1--,3@+A&0C+?B#B+.F#2<BE@"!D#B31H:1?3D93&%6#A0?
@r6236
GACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTAT
+
3G1)50#;,71"*26#>?1+-!HA'>67&8FA<E=#3FH15?:G)1!
@r6237
TACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGNAACTTAAAAGAGAGAACCTGTGTTGCCGCCAAATAAATTGNGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTANTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCANAT
+
./H#A>HCH4B;#+60F$$4=(C437-(B+$&0:!8*'-85?6270C6EF*:!3-%*3'9'A,:8'C:>$F<*2/!4!"C0&*HHF62()>(:@+=CH;=;167:/65$-B?G:?6-<3:H+5@-!,.?99C97:!E>0:7@';<$F<#D.+8B,0H5129=%9(G?EE?")-9>+#2"!9@>>#-!F>"6&*E&.4,2*);8C=)E-C"/B
@r6238
ATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGNCACGGAGCCGCACATCACCTGTAATGCGTACCTGACCACACAGCGTAAG
+
9A:C8!4?+/.E)A"<86?C3?!+%2'C//-A(>&H$*/!GH90;E99!(C?G>,A04&C%/E)?-,+DF69D2@52%F,/A01@%8E=654#7D>/*"=6-A@G##%44&8@$=-4.1)3'=)5"56@DC5!4C-1%/!86,*=EGAA<,,-5675C)F8)D-:5C1-H&#*E<.F#B&(?B#$%1-*'&$6#:+"#(0E("%E826:6849=C:6::>"89)/F!H$"#$$7G*H++0A4),0BH7>+156838CH)<<.+!60":%%*)4BH?+74?(#A.)&3%/8=C.&&,
@r6239
GNCCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGGTTAGACCAAAA
+
)$)++#++&&&)#*"*!&)&'+!%#(+*(%(!+)"&")&$)$'$!*&#$'()#$$$"$(
@r6240
NATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCATCACGCACGGTGTTAGANATTTAACCCTTGCGGTGATAGATTTAACGTATGAGTACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCAC
+
!6*/*-F);'D*>F;'F6)A-@D:ABC#$8*B!&5&8%';60G>EB7;.$9C0-#9:#%7=',4(+$#;"G"3&/)E$-!2"$:+=24,E67B9&E.11$B";3?>>?5E/+@F22F&2-1)+>,5<C3"(3AE9C/0303#3!B),EB3?--F*97)?;$DE8)7A44$1"/E6<
@r6241
GTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGC
+
2>3H6=9'+)C6.7.<9;433=3,5!#*'04D$B16AC9$-
@r6242
GGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCG
+
0#?G:=55,E9**A13:#-,!1&6G"$-998)+$$8FF$$F*5&7!F;$.7=0:;D@2G>4
@r6243
CGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGAT
+
7,.DCG.G2B?%,'GA0#B*8(*/6A,?=)/29"D$B#HB#-H7
@r6244
NCNACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCGATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGN
+
)$$+(*)&')"()$*)$")#+)+)%%*##*)%'"*%!(#)(+!%$*+%$++$+!%+%$##)+)"+'$!!!(()#')**+$$)$#%(()&*)'%"""$&(%*#$*"'(#(*"$*+#!$$)+(*(%)%+'%!$**"%))!)+)&%!$+#)&&*!!'"#%'*&#'!(%)*"''&"'+!%#+)$&!!!%%$*+'+
@r6245
GTGTACATTGCCGTCGTTGTCGGGCGGGGATACCGNTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGG
+
"&-6CD)-?"%G-"<'>7HDBC-5&4!B3;=E9"7*=";?&-8A-.G(E%@C3)(G(,.0B&2CB28G-="DF)-88AA:.*;/"#(-=.%+B8-+
@r6246
ATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAA
+
.F<&0E;81B)5%317(1!23(5-(5DF!,:$*<H**G!5
@r6247
NNNNCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGNCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCNACGTC
+
!#!)++#"($#+&)#)"&'!(*%('$*!"(%#**+*'&+*)$&!)#"#!((*$$*"($"%'%)%!*'%(#**"(#)("**&'%+")!()')+("()%)'*++'%(#%"**#%+**$+%"+*
@r6248
ATCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTC
+
"@=*>;!'(*EE!*@%@=,9G2<:@B@B3>-$C*25!%':%D;D-6%H26
@r6249
GAAAAAATGNCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGNGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGA
+
6!@/30!%"GB9@&6-+001631@C99(95="*<@,H';7,>AC=+#$D)/:?%:@97*;5C#>"1=*B%BE,#C9#5%4:::)G'%.+"<H,)0#$E4655=&%H/)2C$':9!+7.
@r6250
CTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCA
+
E@%<?)7*!24#&/=<<?4E6!60@?%2>6C2#=D<,-A667EC>E4H467'B,)#(B&5$:A%D5=B5))8-7
@r6251
CAAGTTTTGGGTAGGCTGATTTGTCAANCGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACG
+
->592=H3+"8B"%"7H7B7"!0G53B++852C1B@CA;=1=H&0)?#G(1/-7*+B4B@?**!%$"A/'22.7#3#?H=/
@r6252
CAATTTCTTTTGTGGTGANGTCTTCAAGTGGAGCATCAGGCAGAC
+
)(>-D7>=H=++#5HG$4H44-7A8@;?+AD=D?/+*.C!9"<.6
@r6253
AGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGG
+
"4&5H;GB#:0G$;)-;$+EA#!:GD"=!.76=(%@!,DB7<8D/8+E+5/820D&,;<,05/
@r6254
AATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAAT
+
'49C/G>*0DCE,7%&!C2.EC7060)A!CC73B.7H7$1C*&E">5,@/2G;?%*&0E&:#E(G/#23+67*8+0+06+CD?;;)<83&D3@<72'F%4
@r6255
GGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGT
+
9@=.H,H&7E5%#62@0G6<@1AEG?."E)>E$,-&F/-<$:*%D;A;!H/D$(2#B1@8009-$';D;!?=
@r6256
TTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTT
+
-?&.F"(%4H89!HG"+.*B'?,>>B#=.?%>!G>+8;>*7&5;/+@".0+2&!)2B3A9*7,C179&E>,.$=9@E1E94G!-5%B6"#
@r6257
CTNGNNCGTTNNANTCAGNANCATCCGTANAGTGTTAATCTCCTGCATGG
+
"*$!!'"%!*""""$##'#"%*#'&!%($!++'$""#'&#&)""!'#"!+
@r6258
NACNGCNGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCA
+
''&!(#$((+)'"%(((**&%)"'#")#!'%*))())%"%''*)(!''*+"$+*"$&++*(#)%&+$()")!(#(!$*($+*$)#*)")"#&(+!&$%&)++"+)#")%)*!')(%&$"'*""$)'%$#($(
@r6259
CGGGCAGGNGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTAT
+
;=='5=;C(G-@$E42&#;$F>E7D;9#E%86FF>1$%!%/FAF>2')+5F,1'&;!)CB@G)8.!)4:;.9DE'>G"(E(C;296-#-E.+C5'%!
@r6260
ATCGGAAGTGAACGAATACTTTTTACATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTATCTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAC
+
<+H=#H/478-!@:*E45E=A&1D0.F:B4590+2;5D%!";:/55!"3/#1F7>9.=HCB8.$50A<<G,>F11*&"A4A:CEE(#E;5C967C%1'7,'D;EBAB==@>(C+-C'6DEG8;E?G=3AC*2H$%&4.@:'6*C=6C=&CDC6H;&
@r6261
CCTGATGTGGTTAAAAGACAGGCACAATCTNTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAAGACTATCCGTAT
+
A48::-2-:G5"%+2#;E>7E+3D!:/+G6#$3*8D97!9$9'7%*1#?5>B=<E#"@"-BD%&;<+A1*?3*D&<=91F8;(63<80?$C8:3F6CA=G?@6-;);A<>:G,B9A+C6-.BE'C>;?+2ED60
@r6262
NGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGTGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGT
+
0('D3H0+A*>@E,?C0?%%F#C6++*9.:,1598,-8F64',>%47);.::;B5@C?):%&DGC?4?0#:5#=69%749#-7(9!C25@?1?D+>
@r6263
TNNCCAAATCTGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGNAAGCACACCCGATGGATACG
+
&"!'*)&(!(!+!"$('#"+(!(++#*!$$')!$!(%!!**")'''*+*+()+$(%%%!%$"$#*!(%')'")((+"*!(&!&!#!!)%#%!##'')&#+*#"$+!*"$&%)!+""%%#*%'#%$)+$"#!'&+*'%()*(%)$
@r6264
CCGACAAGAGCNTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACTTTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCA
+
=4<9?H;4$.6>AG=*0$H>)+58&=*):B$C=,G="E61;,H?!+F=>;*-@*.=C%;-HG#5@A(=#1A$71%#7*2*G?A:%*6D@A2/:;1"G5&"DDG,0FG7%C8>E=>8'58BD8;G3-907/E>6BC(6D7%&3G-"1
@r6265
AAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAG
+
C9;2HB)E2!(=G"!%!G/5D/9(D=78F?#F;45#?*-=!4(!
@r6266
GNANNGGCTNANCNNCANCNANCCGANTTGTNNTGTTCGNNNANCNANGNNNNTNTCGGNGTNANCATAANAAATTNNCANAAG
+
"!"$!$##$!#!"$!$!!$!"!$$$!!!""$##!!$"#!!#$##!!"$#$!"#$"#$$#"""!"!#$"#$#!##""$!!"!$##
@r6267
TCCGTGGNAATCATGCGGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCANAGCNCGATGTGCTGCGCTTGCTGGCA
+
(+!&()!+!$#+*%)#"(!''&"#!%$+*'"")*&##&&!()*%#&#%++")#(!!!#((*)#&*''"%"#++""%#((!++**$'))'#%#$!&(()"#&&*'!#$%')$(!&#'##+)$$*)#&"+#(%!$*$%+"((*("#**$"!!!"#$)(%*(")#%))&%#''*(+!#!)&)
@r6268
TGAAAAAAANAAAAATGAACTTGGCTTATCCCANGAATCTGTCGCAGA
+
7784C?';B<-4!EE'8+80;*%,7?!:-.&')#7G2*1'4;8$%+4C
@r6269
GTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTAAACGTCGTTTTAGGGGATTTT
+
80A6%()BA)8<<$<@>44*3<4H3G>?5G1D<E*H1"-D;/70<14/*29!7)5E5<(1$#=?3*4F!))8+24$,0!8#6-(G-!/D(.=>
@r6270
TACACCATAGGTGTGGTTTAATTNGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCAT
+
D+6--@12B'7=/"<4A?7G&#4G9>$;B/(%=?6,7?,A:=<<D!$B+/;($*7>HDB9B=&CD!F$+><$";;D.#*)6(03"HC2"$G872;4EA49(G-?)?&<#$)/;&.@
@r6271
TAAAACGCATAAAATGCGGGGATTCACTGGCNGCACGCTCAATCTGACAGGTGCCTCTCACTTNTGGCG
+
+&6&D"DF6?#+(=.0(+52>B5"D-;#E%-&AD!+/DH=739B$/46(A.A)($%,=D').645/A7F
@r6272
NTTGCAACGANCAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAA
+
#8&G3)E"B6>8640$828H49!6BF=D.9&:5/FGH7,@$!@&7?->G>)*=D&"5?H#0('*5;+5;5#>*1='#45'-#2?<A?!%/.*+496@4*D':1(&>:H=G326GFE+2CG1<53.ED8:G./G2D#2&/!6A*=010=+(9&'19-(+.F>207#;%DE$5.5C:)7FC?9(C/F#/4/?'-*:*+7'">7784=/D3CF)E@D)3B9#%*"6<C5-6'GF&4'(3%?/9'!?3+?->.!+(37>F"H$;=%()2'&=;)")-:F/,(C"H(+830*=18<0219@
@r6273
GGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTA
+
D@")@34=3CG$%<2(:8+=+*"F$9/.#B(:3,;'9GE/&H#H6C'?"8-7H:)9!*;106CG%C(,/A)E;=%@32D>-A1H":>?G?<E
@r6274
CGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATNCCTCCGGCGGAG
+
,@9667.6$,;<:/&5=;?64:.61&:'&-(%3+#B7!%70B3<8CB9C9
@r6275
TCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCGACCTGAAAACGTAC
+
8&AC')=?)%,(65H+-H@,94E;'.*E=9@!-2-F:-,0?)/&&;7/"..?C(B0<7/F63463@2"/5?3,>;19*,".G=)F8)
@r6276
AGCCAGCGTTNCGAGTGCAGTACTCATTCGTTTTATNCCTCTGAATCAATATCAA
+
27$2F:*?@0&-HF(*F,,C?:;*/B&A*%0GC0.8@)/"<;@H$0?7,=2A7>H
@r6277
CTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTNTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCC
+
GD;<,:8E<),?#A/8&$+$)B8$5D7@9*$+"2E<5G&?%=4EB@2:$B9;!?5EC>%GBA%FDHA.,-("=,<E8:9"'4'>281092B+,!<C<,=;$G.=?<%7$@
@r6278
AGAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCNGTGA
+
*!+'(!'#&(%")#()!*'&%!!)%)%$!%&&%*)&%(&'+%('")%*&()($)**%"!%)%(()#'*#$(")&)++*&'+$"%*+$*+#$&&#'&#*'+(&"#+&%*""$)%&$$!()*((")!$*'')'
@r6279
GTGGGCTAACGATATCCGCCTGATGCNTGAACGTGAAGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTTANAAACACAGACTGGATTTACGGGGTG
+
(7<+<2$1<84:C+&%@C+(<-"C-#1E*E!E"C2%%=-%F7H**EC+,)/2://6)"BF;5)H>)!'14;E&6<F+=D/>G?@G6&$/!A06CA>.>=>#,04AC+$=E9/5)C:,"7""!/F@F5D.."..:6"'G534?'$F-#162H(?6"%"HAB3>A4GF2@:/<*&/<6?H4FE150B7?@(B$!#0"-(/AG4FAHC'3H88(F!9"0@BD;=*G?@7&265:C0'7
@r6280
NGATATCGCATATTTCACCATGCTCATCAAAGACAGTAAGATAAA
+
!'(;/*=-#;0:$8DGH=!C/&<*@34<?.="63.?F(68/F&A*
@r6281
NGGANTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGT
+
!1.,7F6;9&-:-5C9!'+:"+69AH9=*F;58>0>%!G4B0D
@r6282
TNACCGCAGCAGTGACTGCTCAAACACGGAGNAGCCGTTATCCGTATNCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGG
+
"%,>C;1)>(F(88FF<-'$G+B:@E=8F-77:9':@9,3A#;(?6"9H#D4$$3G(5'8C%/A/!2EA35"';@!!+%);
@r6283
TCTNNNCTAAAANCATNCGGNNAGTCTAATNAGNTTNTNGANNNNNCAGNCNNGTCATNNTNTTCCG
+
$!"!"$#"$#$#"$##!$###!$"$"!$#""$"$""!""$!!#!####!!$$"##"$"!$#$"$!$$
@r6284
TTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGNCCAGACGGGCACNCTGAATCATGGCT
+
1BB::9'*&/B>0*6>"!@';#H:!F:$<H;:12$9;,-.19!/(=E*$:6.4=+=B>7&).GB?5*"F5G(,F.-?E#
@r6285
GAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTNATGAANCAAGCATGTCATCGTA
+
#*%FB874B;$3;=;6;/%743F39443)+44$B/H8,+75A.7G%:C*H<-00@A<$?;#D;BB(E?5E1.!?-FD)!E(/
@r6286
CCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGC
+
-2#:$9/?($G*.2.@,=40@2<E<(-0@4B6>G=$$G&<98=!>#')(:?4'?-C5#-#3>5:96+1:#&?;,.<7/8)+.A,H1:,+2=078-29>34+ED/236AH7@*0:,C3/#!>!(HD0FD9&2.8,;
@r6287
TAACCAANATNGANTCTACTCGTCGCGAACCNCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTC
+
&*%*%*!!**"&#'*"+&+$)(%$(%("%$*)+!'"'+&*+()%*&+$#)"*#!$'!'#)('(!!!$$'(#(+!!%$#!*)#$$%##*!$'&+%(
@r6288
TGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTATTGCCAATGACCTGC
+
8G%:<5'H4>3)=9%1+4),34F=$*'F#G#E@.+4$&;"8E188!,ED10<8(7HF@D%=2A1.3/+!"-E6F<!7
@r6289
TGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGC
+
+H@FB.$'7GG5F3)&F%B&E<;9-9/@8)5C>=<G@?G*%+=?=7;C<5H<$2,.0=(-@"C&H<A-/3)+0>:&84>/H
@r6290
TACTTTTCAGTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCNTGTTCAGAGGCGCTGAGAGATG
+
!%+$+'%!($+&&&'$$%)(*&$*+%%&#+###&$(&%)*%$*)(++#&++!+*"+""'*+$')#%"'!'&++#(#&&%(*"
@r6291
GGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGANACTGTGCCGGATNAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAANCTCTTTGCATTTATCAAGTGTNTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCNTGTTTTGCTTTGCTCGACA
+
3-A@H-!!%H?1$973%;D=/,+0=19?<F6#6-&*C?7E==))%$D&96H,?E+>?BC=>72)<-E&E+<?<64569FF+C#!6189B!-A+2E)*>954?4B60$6;G=/61FED)/$(1FC'D6A>86B&1@))8EGA?6@DH+'GA1CC=(A47!%9"!>?E90&-;H7$=C5()=,H%?!2&"6$-CDD?"<<A4$'&;-?@B
@r6292
AGACAATATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGC
+
D'9#+,EC9!C"?&9<!*-?@AC/!32HE?33.1B&:+7&$4+%A");D?B.@%9!@7G@->:!>)
@r6293
CCANANCNGGTNTACTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAG
+
"&#("&%!#&$!!#)((*+!&&"*()#$+*)(!$"$"%**#)+#%*(*)$%(*$*'&!*'(%#'#&(''(&$$&!$'$
@r6294
CCTCTGGCGTCACCGGGCATNGCGCGCATCTGCCTTTACGGGGA
+
1&,:7=--D+0A>$42)?2HCB1=C<9E-$1H/60,9F/&H93@
@r6295
CATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTT
+
CC=&)@G2AA.D5FC>''4F/8!13/0-&)5%(+=*85//G<76#E<4E"B"@(
@r6296
GATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGG
+
90=.6(!H9%%/3B%8,4B$2<A%G))"/C=B/>DH0HB:24E;2?5,(
@r6297
TNNCCNNCNCCCGTANNGGCTNGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGAATGACACCGGGG
+
$!%$%(')!$)#("(''!**)!+("'+'!'&"++()#""!!($)"('+&$'(&++%'"&"!))%&%*)'&*!(()(&"(&'$%"'!#%($"#$!))!''+'!+%$+'&$()"!&$(+*"#%(%)
@r6298
ACGGCACCAAATCGACGAATAACACNGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATGCACAGTTAAAG
+
81,#@5G*'CB@C@=@;+4-/<%5GD:">?2?H/:?:-3+.*&GFB*#;-#9E?C%%51+,,>A(/=G>5%@,E>G#%05;8(90).(4?&1%.2-2$?E$.&#%%EB*3=13A>:).&!2H6/.>>D10)/76="'.8"&5FC/4.7??2GB7,4E)#F+736=
@r6299
CGCTTGCTAGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAG
+
1.F!15<G933:"(D$7CFE?C)("5"8+B<?"@<7-C(5=-2A&8!;$C*3?4!<A=8HA%<.9C+7"-F&8
@r6300
TCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTNCCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTCGTCCTGCCGNTGACAGTACGCTTACTNCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGG
+
D*47G?D-65,9;&F?A@9;&E,$'-6,*$@!;D0/<D;9*-F9@E*-F'(,GD%"@$/>6<$#+C?;;6DH9"H;1&'=>HC@4&+B5+%F1+<8.:8.>B?@8F,7*(;1*G#$8))2119!92>$"1*A82:7/G(1'A7!B<3A01'H">'F%E66>:8,H3/(2->1A3>2"1D$=+1!<H&.!
@r6301
GCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCT
+
CC'=A*-=5+1!(47'?FE#$F"&2@F0HD5/@(F$56C23A!BB1E-1:FGG
@r6302
CCGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTNGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCG
+
(2G";:3;&E)BF'6!8.7@8A6?-<G&7'"0>6!&*8/BF@CE0@8A"2CD5B;1#>#536H$A3CH-C:5%19F&)/(!-8+!EA8#A)$'1"CF&8'!+/4"3HB1")C*.;=C!1<BD'5&A6"?AC@*'&A/7B
@r6303
GTTCGTACTCAATAGTTCNTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGG
+
H?;',+/5'G1H"0?F>&+.B6-E2&0)C7&1'%(-2H655.+/<:!CA<5E9C>'"0462#9.%GA-8E#4%,3D>6:)16A>$0>410D)-F0;-'80"?%)@@'<;G<H)20-ED(E=22&#?E(A.AB?"'5D6BCC'3E@"=+(4!);%<8"=/1@-1H#HD5F9#2>3
@r6304
ACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCANGGTATCCG
+
/G=9>357=62"@E--=BC!(>;1".H2D1)<A&331+=6:+==).&D@"E4
@r6305
TATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATNNTGCCTGTCTTTTANNCACATCCGACTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAGTCGGANAAACTATTACAACCCCTACNGTTTGAAGAGT
+
'?#A%,H%,7$5%*,(1#=)C6&,-<.2.2/&3F&7>:,:C=48&B6/41@+4=5;F1A(47@?/G"E-<H;B-#F*<)63>5+;>?86"(B'A46:06;=35,D(7>(CF.5*>96)'BB,,G%>A:<!<E;+
@r6306
AGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGGAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAA
+
0D>%!!>DA#,6?:*/??/A:A=F1(B,:G8"."7F,8).%;F",2HHHF!#<$9A#>D0*%B$1,>@#"0(/1?"/BD":,@$,#*)&H-&,CC%(&*>G@'3G?'3,G1<;035E78'.)<+-:A1.=7(143<;#70*19.$>#C6!>2?5#(;-C6
@r6307
AAGGAAACCATCACCCATCATTTCTTNGTTTCTGGNATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAA
+
HF:C)'816-!7E:/*,0683B'C31,88)C(70&>%<;5=)<6FB&@D,%2<!=G9F?/+/%7*$B&-!8BHC<*>)<:8;96C+E:9.&#C.5*=#
@r6308
NGNTGTAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAACATCCTGCAGGCGGATTA
+
!)%%)%++*)"#)!$***)+#$"!$&$!&!)+#&&+##$$"%$$+%+!(!&#!##&$!%!#$$$&(*!#*++%%("%&"
@r6309
NCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCCCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGAT
+
!B%:$>&23"9D;.71>$E8=%-+B030E-/$"F@07+$+8G1-A(4%B%+4=,BB2/-2-007);$1;8>'$GF3B0$;C40%D*#H24<!4EHG&%=>4,:$#&*7#3!B9F7-C#,0+EG8D=&!D44@10%?G,-)G6"*7(GBH>1&:8.
@r6310
ATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTAC
+
B+3<"7>F<B@)5,<<H6B,-09C54'B)92AC(?@6!H$,61B9-?.H#(.<=<C4
@r6311
CTAANTAACTAGATAAGAGGAATCGNTTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGC
+
D<"+&"?4)?9'B$C!)(7">3**D9'B6#>/'A(%E#6(-5!=5)1(!,7!?3'7G9,AC9B*4D@+95.85EE/C/3'HD
@r6312
NTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTTTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAA
+
*+%)#+")*(%+))+++'%#%'%$$+)!+())*&)&"#)!(##*%#&%"*##*)$*'#&#("$#+($""%'%&#%'&*"!!'!'!%"$+*#"(!!(+(&&#$&%"!"%%"!+(%()%'*%'%##")+&"&%&&##&#!$+('
@r6313
TGNTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTNTTCCCTATTGAGGATATTTACTGGACTGNATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGT
+
'%#(+$&&"*))(#!#('"!!+&#!*!&'*(*$)'%$)$&+++%%)!++!*!&"%))*'!'$+''+)$+##*'!('%!#'((++**+%&+*%"'%))*&!')))%$&%!+$''%%%#(&#"("%)'*#&(#&)'$%%%)(%'*)+'(*"$&%'!##+*%)*#%&"&+*()%(!#"#(!(!!*'
@r6314
TNCCTNACGNGNCNATTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCT
+
!)'&$(')#%'*#!!&+!'&%%"!"+*&#$'("$$'"'""%+*'%('&%)*!+"($#+#+&+!+(%%
@r6315
ACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAG
+
9?FF)#30$=D'%DA!73'D-G)/FCF!&A2#*0?>=7.GH!194-6BE1;1C(D(D2BD9HC1
@r6316
ATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAA
+
8.)54A$BA@,$E5()$3(BC%81!E=1+$4H51*%6H4*#EGGG'2=%G<5)F@>4%1C+F%27<;F(""#!/'+,1?+6G64))($#'B:0"!G#=B2*.!)E3)0:)/*#?:A7G)D1>027=*2*;%<4,/@116>18+F7
@r6317
AACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGNGATATCGCTCATCACCGGATAAATCCGGGACTCC
+
%1!)":2D7)&/H")-+?$(.3,%2BB?4<4?(@)'/A!1>G+$F.#C.779-+2=.*6+*-.;6&.D,G;6H&&06#4<C3A09F$17E7D65G,!+A93(*4=4CB"?>HG*A,
@r6318
GTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAANGTGTTCGACGGTGAGCTGAGTT
+
"9H670%7->6+5@%5F.97?8HE&%9,<GD:GECA;"$68:.*</.@F4!0:B*-!0&F6.4."!&>+8.%9('/F&<?=225F)2?G0,'F32=2+7G*?H07:&;HC$!-52
@r6319
TCTCACGGGCAACCTGTGACGCCGACTGCNATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCNACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTC
+
B86A;.A=-84"+>2@H<74$G.G"E!&$@D@'$<2#<C.7%)A=4BG!%:?FCBFA0(=AG)<'&1.%8'9!A1D94,5$1@:/;"8F?3<FA$.3A/H,3<@B//H5'$"++B:@75+D,#+CE?$@F9G$)H5,,,H+7B)2&!8H/11))*
@r6320
GATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAA
+
C(:.2&/=2A>+/!6=F1H#<-&'+1A9D<<5B:"%AF%"E582A:G$/'DC/>-4*=*>A;?!F4?106+D*.=-2C&.D"8@:-)G
@r6321
GTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTAT
+
?#-"322@53G%9H3**$';4;GA=3)<1F@53+#%#;67)!)$G0+%:2.D#8(4D
@r6322
GTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGTAAAGAGTTATGTATCAGTGCCTAGNAAACTCGGAAGATTTTTTCAGAGGGATCTAGA
+
-5AH#/12*7EF6"+6A'$+&>DE&,+='0<0@F62@<&:0/,6F=?554F"03$7-D%2/.*?'%HE@6,(;5#B;(;=,=&5H+C*D*.+2-%H/-D?68)*/5F)&<,,<>"@5?;3-034*1(&=6>%EAG!3
@r6323
GCACCNNNTGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGAGTNCGTCTACTGCTTCCTGCCCGANGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTNTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGNAT
+
&#%(!("%#+$($!'&)'#"'!"#&&##*$%((&%+)+#*$+'")"'%#+&!*&)&'#+#'%+#"#&#"*"&(%!%'$"%)))&%(#!))""'#%)*"""&*')!+!)$!*)+)++*!"""%"*'+##)*'&*#*++("()+"&+)$$+*)""()('&!$*%'+*&)(&"(!!"*%(%$$#"%)"&&&&#!#%&***&&*#$&*+!%"$)++'''"%%*"#"!('*)$%)#+"*&%*))##+%*(##&(''%!*'%'%#'')))+)((%!+$"!!'*(&%!&!$(!%!+("+")%%)("*'!()!(((%#'#!((')%")&""+)#)$!%#)#(+*(
@r6324
TTTACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGNGCTGACGTACACCGTGCTCA
+
.C7'&A6,5+20,!!9%;F5)=F:795$.'$,300686(*:(*7@:96:##D/%#-.H)F)&&.-,C3@>CG
@r6325
GGTTGGANACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCAT
+
/8"HB%D%6'2?0",:(9D9@+%@0$,BC2&<(=*'>;>71:C<602C<89E%@B6)-6*C2EG#<(C<F2HH0%16?-;)*=&3GDD7)D;@A#76,:?AC>C=*:D1>DD2#FDHB1<3$E6@=E:0/2&3,2H#/?!$<=;,/<-@C4=A%B?G0;D872/-,FB*1-;+$+$$5.4<CCF7"*.A<&C$0;1E;!H0.%E335H8C?".F
@r6326
CGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCT
+
FH6#F/,/5:HC&*GA"6,2*6##'21*FB+B9A/"E'=1!DC)!=20B57>+<!:G!#5F%91E!',(G;?9>>?.F$);3E(94+05&95%2!-)59%>3(?#:=015GH@@60"FBG2+
@r6327
ATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTG
+
8:1F9C?5@+/7B!82=230,F=!E-$'?9'?9?10=2>2?/@14!!ABEB5%E
@r6328
CGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACC
+
63<5;3#"166F),(GB<3G9#69'41"+;3/6($;EE'90%#9D"
@r6329
TNCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCNGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGC
+
#%."GGC!11HC!-5>0-FC!47-&A5*+D&74":E66=H/2.()@%@B1;=@2&!DD3-9"@$?=8!87,)B93'F#%D"3#52B+8,<'4:>G4C9A&H6'!D+)0'80B">2&,@04*0!2<>@@"F@D)=,3H,C)6"08-;!=F5&B%(A-AB.)!04,D"<16C*!7./BA#&8"'E"&(HD-C0+B%#13-#@%D"
@r6330
GTCCCTTCTGTAAGAAAGGGGCGCTTTGGTGATGGCTATTCTCAGCGAGC
+
-E';F:*'"4B;,@)93)9H50&C<%:<-!3-&(*(4+@,7='-<5)2-9
@r6331
AGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGG
+
9G*/$2HE03253%/+*=,''D83>":120%1$)!7HAD@G>=);<0-6
@r6332
GGATNNCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACA
+
($#&!+()'%'%"'&(**$%#"!)$($%'!(+*$('&&(%$**(+(%*((&()#"#!#'+''#!'(&$($(!+%'%#"")"*%+!+%$
@r6333
GATCGTATTCCCCTCAGTGNCCAGCACCGGCGTACTGTTCAGCAGCACGCNTTTTAAGCCATCCACCGGNCCTTCNATCGGCCCTTCGCNGATGGCATCGATCACACTCNGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTT
+
'$+*!#+"'")#&##")('*#$#+"*&&'(&$('&)'$$*"''!!!&(%"$#'%''$%"&$%"$"%+(*&&!#***%%+!"!%"#"(##)*+()%!*''($!***$*&%%($&!')+$('%#!%!*$"!''+"+&!&"&#$&)&&!)#"%'+)+(""*&)!*"!"!
@r6334
TTGGTTACGTCTGCATNTGCTATCTGCGCCCATATCATCCAGTGGTCGTNGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCAT
+
F/@7D2-3D*0$H+EG$G@/'2*?<&<(,$$A:1#-0";BC?B5'*GC"%(A,%D=5FC>3'GE@%=%E.6*3?2,?9?$;:(,%9@-$3.9%2D;+7(+
@r6335
TCGCTGTGTCATGCCGGTNTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAA
+
H1<D)D<+</3-&"@6DA+A!!959/+DFD'D?'B*7=+?D-F!?CAEFE,H1C/0H4-@E/7'C3*H.=8;@6A
@r6336
NANGCNTCAGTGGGGTNATTCCAGGCGCTTTCGCACTCAATCC
+
!%#&$'")))&*'+'%*#*)!"$'''"**%%#%&%*%&$%(+(
@r6337
CACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCA
+
;-7D2FH<(-?7-<1<;#<*%++G*$*0B>*.=0+60,@)%/A0,(6,=@;/;E;>B0H5D5G4!1489&'9/0='HC.%<+-D.44H5G&=H%,/75E<BH-5%@&79;31=@H72=#)D-@DGHCA0-<H>,<43*?+,D-'G9$A-6D#76**GG%GH-
@r6338
CTGTTCGGAGGGAAGAACGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAATTGATG
+
7;-*F+>D+7E>6F4H+)&-DD->+144%>$DH!GC)'>$&:.,3(+=#AE%;C#1.+GA7
@r6339
ATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGNATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAA
+
6#&6E4$A4+74#F957.8:-B8&/3!"'C<*:4'3-#53*E??A-EBA+=*4A<C5)<(HHF(AG-61<F%/<212);E=>70-//:50
@r6340
CTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCNCGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGCCGGCGATGCTGACCGGCAGTGA
+
0F+8;#7D6!58A4/)C;/;.49066B$&$105:DH*#4@E?;B:.'(/('>D(83A.#:9/9'"-3=1'GB&F00%>88F8$?@9&A0;2.8A6H0!%$))<&7=:E3">+4#57-1F&C.5/06)<"E&#93+?(EC->#,C(;(&-
@r6341
AGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGCTGATATTGATTCAGAGGTATAAAACGANTGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACG
+
-=*>;0?HE+=6B)=B)-66GBD'63"$C$,-.3A1*F(7BA851&C11()9(41"E,>E8<2/'H72CE.2-)+>;+-!9:B0%7=)HH7+DB8#+2)@3H*:AA!12%6'D,0G$>84C"<:,2"D?41AB09<A'!
@r6342
GATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGNAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCT
+
1!CF&0/(:A0!=?=5F!3-</99"&.3#%B@'0(H+4F#+'-G73(:0(D*;-&<9$%=&HEA";G!:%D#-30B&3#60F.C@G-,'/,3A*5(H#51*@A$08'&A2<&8F7E1$7&H3*::"6D-3H%&2D83<A;4,F)!F(;A7/!2!<-=%917
@r6343
AGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGTTGAAAAGTNCATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCANCGAAAAAATGGACGAGG
+
>#?1)&H4<(!2#04F1##66A!"$3;B@F@A<8>&/)F=F;/2C@#5(B,*=#04F#$4#;'**0-&*0''5*GBHCH4AE1552)F.085>235,34CE&7=.;C%7344+D=($8C%7/7DADH?>2!6H'3"7BD&0)G&44>(-<-;7!7@/1!D0"-E>B8G)!2.;6!*G00A'G
@r6344
ATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCGGCCCAATCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAAAGCCGCAGCCTGTTAACCTGNCTGTTCGATATATTCAC
+
@11-(4=9)G%:<@=C:,(F=&.30*<$$'*4'6H5&>/)2.6.<**=#(A/).>D2,)G-669-A8!5=-"H#*'%3D5;40F%+49183H@=B)-2"=@=)*@'#%(*?@$>8*(8@;'&,0G,8!;%H;+4%6></863CD>@,4'@C#C%#)G:?0AH/D6H!$EAC)0)E?.)7?4(&;@A1"BC#
@r6345
CAATCGTATCGNATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGNCGTGTTNCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAA
+
.>&*&?D,(+"AF;!%0*.!"G#G:&,@<.=7G;/.?7@H*4*5+:D3"#*)/ADDF74@B!G!D@,A2B:)E*0A21)>:G>H:9A!*)-!/):?<->'$=A/)2'15%9E8*3)86G#D(75E2E64.3!)7%9<H6/CF=(G>*C=E$*HG+HE:-(7E<%2
@r6346
GTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATNTTGATAGGTTGC
+
E</&5+$2%H"A8*;0B7+&271;(!4BE652=!*+%*>916<B4/@//-A-'1F41D-E:2G=CB8@7B4&-F0(E<:,+E$0!)D%=(/2&5G:8=-HE2+
@r6347
CCCTAATTCGATGAAGATTCNTGCACAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAAC
+
E/)(8%>@2C-.1=#(19CBE4;+<%4$+D*.C!35D@$8%D7D/FF(79;3=1%H#50>1G#H%4=;2#@4D4;'(8C:&HA#F"F=0)+%7+#'C98$15%F&%<+>)$0607!A
@r6348
AGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCNCAGGCGCNCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTG
+
E(#2A>A354:!;@*G.;%H+2F#-5'2<B-E"/B4C&";EH>":?G.,2-*FD9/2.>D>A):"C24CA5%5$D9@14D/<A>?:-&60*$?F5>?FF',1!D4C:&?#)?*):)6%*3(<'$37!E);F7)9D270-,!>./>3+<5%:!&1B+?%)BG&3BAA%3DC7.H
@r6349
NTGAANNATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAA
+
'&("%#&%+#!"#&$+%$))*')+*(+%(%**)!&$$*('%)+'('*$'"&'*(#!#)#&)'$!&&
@r6350
NTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCG
+
&A6*!H1H,-F)@+/6:,2.%5:2.*=!)C/904D*#:#%B(/B-G5*6F%1!H.D)(4"/*6$9(/H/=.;;.2;8FA'B(2!+>0?,)6*5"=7&#E+<;!/0;0C%,0.?/?/.1B1D*:
@r6351
CACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTNGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCT
+
*>1061//)H-C+8(',2-9+0C*$<%&<FC1F1B4(@&727!5A(:00F<80C#4B>2+GA&%)D%%27.@0?.A:-29)$F::@3."#!12#2%"H!?&>BB(<F(8;B6:10AH)#8&/*C+7*3D",">9H?(:4*('"<#4729%0@1>%?86GD*,DD'.)<
@r6352
GAGTGAAAGTGTGGATGCAGCCCTATTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCNAAGCTGGCGCTATCT
+
&+'"(#!%&$$""#''%$!%)*$$%'(!!"#*%)($*&%##)"*#+&!*&+&#"$$$"'$$!%)!+!'%*""#(&"%*")"+("&"!'!)""$*%($(("##($('"%!%'!")&$)&+"%+'%"%&#%()$%#'!*%"$*+)*(!+!$"#"!!*(+"&"&'&%)($'
@r6353
TAGAGCGAGAAATCGGATAAACAATTACAACCCCTACAGTTTGATGAGTATAAAAATGGATNCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATNCCTCATNTGTGGCATGTTTNNGTCTTTGCTCTTTCATTTTCGCTAGCAATTAANGTGCATCGATTA
+
%'#+)!(++"*(%**)!**+%'(($+'+"+++#($"#*($)$&!%*!#"''(&&$)+$(*#&)*!+!)*(*+$&!"#+&"*"!##'#"+'$$*%!("&$*(*&&($'!'!"')+)(*(+)!%%(#+$('*&('%*(!)*#$!&*)"*')$"#$%!(#$%&'"$!'+"!)$(&!%%%&%)'&"'!!#%('(*%!)'"+)(+"&*#''#!$!*"!#*'(**'&&$!%(()*&)))(#+#""+!#)$"!'&+("%"%(&*)*$*(&
@r6354
NTTCTGGCTTGAGGTTGAAGGTAATTCCATGNCCGCACCAA
+
#2B8%8;,HE669F;ECF(3,(H!&:E98%A*GE1"8<?9B
@r6355
GGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACA
+
DA+>@?;G%FH09/+40@AD&./">G136/H58=+)&=<DC-*)929?78<<H>.>
@r6356
CTTAATTCCATCCTGTTCCTGAAACAATACAGCAAGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGNTGGATACGCGACAGCAAGTTTTG
+
E1@'%();!<&@F;&2(511EB@"',A*..1F$@-'9,)!HD!F'.@A(5%+$671:>7"8D=H,*(;5/2?2.B<DE(?(+(!<FCG=D(+<33;E6299*B&3>*,89.<*08+
@r6357
AGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGNAG
+
1'54:AB&FH8C4103;",'B8/9'<58)5%<A=>F,"*&.G,%*>E6&&8GG,+7):=<""67$C#)%:*1%+4F8G=04C3+7)@/;A=2@2#&"GF#B@+1F"H81,,21>934<2'G:D%(1&H./1F?88,G5EH,C&7!A7$.'2F<+;C-13?%05245D$"#HF5#,F)+.8&A3DDGCGF
@r6358
NTTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGNTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTGTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGG
+
%FE>(<<')EE.>:/''#63C3A392,.*G7#@G#;BG-$-!(45%81G'."2--2><1+@=0=&,$*1>1&";!7.D?8=<?'H&4%25!='4:;%=651G593E!HD7AB&>>!+E/6E"2H2A4>B.!7"+?+@D5->%=?)*=.:+"5BEF4,0;;18=89>'4+E*8!,$!,,9>39&.:4'*"66F+B;@)8DF
@r6359
NTCCATGCGCTTGCTCTTCATCTAGCGATTAAAATATTACTTCAAATCTTTCTGTATGAAGATTT
+
#?.G41'8!7'--F<,F93%BA>=-E+&)"D+)3?C93?08!8/4A=G8;':3>&5B9D<99097
@r6360
GGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGNTGGTTCTTTAATNTCGATTACGACAAAGAAATNCTGGCTAAACCTCTTGCCCATAAAGCAGANGAACTTCCG
+
;'7$2G<"F,#A8DC.,1*+"F+!9&;+2EH:D-6?A:;%:'--/3#.$4(<87.1*5E:=,,CG6H<5/4-F3!4<!!5'@?),%?&,4?.=?:G*E.*%"%8GBF?-"1@A>*54=@;E#)45.%GG(%BB9<=#2F@)29$>.-&66<=@5527:$B<:=7='8/FBA(AF&@-!<2GA$#.B%-?CE/B.2(@+,-#7G8!)2-:;218*9D;(:"<#8""AA6/1C=-%F&CC#+68.#.D,89>=(:)@DF;A)1>2B
@r6361
CGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACNGCGTTTTGCGCACTCTTTC
+
006&7-H3C1C';57+C4+>(%;;#>$/'.?(19B7):3(1CE45/%1"!&BC:B%C'E+D@-ACAH(2'+B4(E4;63G%GF,D**(DB6H6C81B#51:A"!H.>+$H84>D$F<B98
@r6362
CGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCTGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGG
+
H?2<3/'!40#*"<E$D,C=/6A=4(2+70@3(8!,535/2&F01,!GH7>)+B5?8*.B//*$$;%:D5B)*0$ED5AG)B(FE+?<4?%A)"&(8$:8,<1%FG))>%,2E!#3,DE"/7%948.,
@r6363
CGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATGCTGAGATGTTTTTATTTGGTCCGAACATG
+
%DCE6"0;?.A5G/C(HE-+6-=)+#+<E3&.A!H/,2B.1C!;1()H88$8/H@%'70H;3H2:#91!4=:
@r6364
GNNGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCAT
+
%&!%&(+%()'###+*+&$##+)+$')#+!*+)'"+'&+%&!)('$)*+(&+"+%"
@r6365
CCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGACGGGTTCGGGAATGCAGGATATTCCCACCT
+
?"'4FF85%!5'H.G9H=(G/7/B&'.&>F$E8,)2D)(>F/G:5EE-8A/1E?;6$$FG99<!51H
@r6366
AGACNCTTTCCACGGCGAAAAATAAATTANCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGAC
+
9E@<HD,8"%32F(B622"&)>(?>F%*/E><,&&-0/AF24>@=:()D#E+3!9=77&G9EEE&1?)#%-03
@r6367
ATTAAATAGAGCAAATCCCCTTATNGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGG
+
EH:1HD.45$7-996;#0%D7->H$'"8D7'!$9"78,.4*7D3G:A.A87*<21FDC$:&=6@:9";HB%4?FF,;8:*/GB*&A7>
@r6368
ACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAA
+
B+(0$$,!/.@-","?DE/+252B84,G(-9(&*A?D%#/*')-E0F-G58:
@r6369
GCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCC
+
CD3=$3(A@43$7F@+C3:+H>?>(?68<@964-=:B;6=#-6('/;F=H
@r6370
AATTTGCAGTTTTCGCAGATNATGTCGGTGATACTGCGTCGCTCTCTCGCCACACGTCCTCCTTTTCC
+
,<A*(4-@-377&%>E83B,A@,E%!,,2=9?<G>'G0%/+<:7)!3F5B'H3+A@!3#!9$C""F(,
@r6371
TATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAANAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCNANCAATTGTTATCTAAGGAAATACTTNCATATGGTTCGTGCAAACAAACGCAA
+
)A#5='E6*59:!E@7*)%.1!EA>@!,&?B'@B67CF:*;B?</E:H9(*C*E:%!7<2E!$)D%HG5ACF<H/=&67>D7>)H,!+#>?H>0"3F.90!<H(E&BE,HG3,'G6-0';65-3,4!C-$+.'28"B@@A-H<86D#@!1;44%%G6?0&EFA@&!.2>)7D%-9'%>?AC51?BA9,!-)/9*E4B1*C'H:'1HH%22?EF?
@r6372
NTCCNCATCACCTTNGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAANACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTNAA
+
!+"'&"("$!*')"%%&($$&++*)*+$)&)*+"(%)"'##$!""*+*"+((('%*)&!'+$)*&%!%"$!))+*$#&%)%+&'%)*!*$))*$+&%"$$+'()"&("(!'!!$&!'&'!&*)!&%#*$+(#'+$)%(!!)($'*)"!%''"(+)
@r6373
GCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGNA
+
<>&C23'D=5H->6,C=+D6.976;%6'7A@F7':BDE2B!(06%"(-2&D783+F26D5B!+G569(9=A=!5H%G0?-6B0F+49G5)1A/A59E#0F?B"EC-5?1A,F<&0"6%0B+$%A44B<H?H$7'E*=H+
@r6374
CAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTG
+
'<-);G5')&AA3!/(/6%=(/><-;E":-"D'+H66.+5A<4
@r6375
NNATGTTNCCNNTNANGNAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTNGTAAACAGAACAACAAAGCTGCCTGATAGTGGC
+
#!&!)!$%($%$%"#&$+*)!("*)'$"+''$)+$*')'%&"+#&+)'"&"&%()"(&*$!%+''!'($#*&&+*($()+'*!##%%)(++"#($+'!")"$"$(#+&!)(!*+
@r6376
AGCCTGCTCAGGGTCAACGAGAATTNACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAANCCAGAATCCAGAATCNCTGGCTTTTT
+
%+)+!('$"))%$"!*"*#)$%"'($#!+%$+()!$+)"%*"))&*"#!+!%'&()"+$&%(*+*'*&)+*$)$*)$$"(###"%)%)$)+$'(#$)%$$!+#*$)"+!(+!)'+%&+'
@r6377
CCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTT
+
5876/E<>3$6/&?8*G<'A59A"(7/""GC->0+<!;<$/HHH
@r6378
TGGCATTATAAAAAAGCATTGCTTATAAAGTTGTTGCAACGAAGAGGTCACTATCAGTCAAAATAA
+
?7<3<+?*D@71+)H".BE65",%)G#%)H$!F>%54+1(5=82EA79F,C6D=H$FCD!/4%9)1
@r6379
TNTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAG
+
*-C4!1@1";-:$9BB6'?@,?@,29.21(&H(79#(!HD7C:>//880&8<**<E/(1.&60<A@*.9@4F59)8),8@HF;:+B6/7'A276
@r6380
CAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTNTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCAT
+
>G>,?80);G%+G0*>75(&%BA48-4-&G"@?H-).6;"#5D;AD;1G?*+:6.=4F/)./2#*G,<7:(*6A50A.)5HA+@=1'D"$!;9B@&*!CB&AABG?A!BC1"(*82?1)%)+D%G?(9%F>:FGG26"G26C*5CF1'741-)(;,2A3F)>F'FE7/%?%!HD!@F)?E#,51*$?<#A?HB+?H8E*''/B4"51-/BCC1>/'3+&5)3+%@#!,/,6=1':+?*7%=+&1F;2=:9,;@2>%+84G92%7"A$!;F3"G3:823A@=/#)#;"!
@r6381
TGCNGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGNGGCACCAGGCACCGCCGTTTTGCTGATACGGC
+
$!)')#''&*&+)%"$!*&")!#!"%$)'"!(*%(*"%"&&$!'%(+)!*&'#%)"'(')%(*''$'&%!&&*+)"*'&%$&*"*%"+*(!*)*$+"*(&)!*!""%((&"$)(&'+'
@r6382
CAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACC
+
+46CE'=:A7>!3$=1>*7FBD":7C+C4#>&/1D&777;7&9C91>%)%->413/
@r6383
TTCAAGTAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTA
+
<?*;6!&2C;04>6;H!'!%!AD,3)EB2=234)835B96&A'G&C8!
@r6384
TTATTCGTCAGAGAATTCTGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGG
+
,?5:<#4G#'5/=32;D0=A;-2"&$F,8>22302%A"11?5HE:B62,A;?GG4&3&#!9#$.+&9H0:+8G??C(C")6E8C/!;$4)01GC.(0=
@r6385
TGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTCTGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATNGAATTACCTTCAACCTCAAGCAAGAATC
+
E6EC15@'625/HH''#;6A1#C+39>48@>8G</?3A$%DC5$/!5H6G/C,&E9EC=0<'E?3F0D/-$="B$6&:G!9#"26CDCC!E&8A4+FB%AA+7>0).9">>8?$9.!;3!#5FE5<+?H(92BB:#%&F#'+;!9@$$0?DE@EHD/!<"H)%-&#0>FB/@+>=?$>#5*
@r6386
ACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTNTCACGGGCAACCTGTGACGCCGACTGCGATNTAGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGAT
+
<D%"0;<9E41=28=33-8/8@#:6%?:A&(0!$=E'5#;+EC7A6;FCD8109EH#'-")7%*C;E994:-.??C*=,-=H'9/>0:+A#+1FF!9>:(-;-<=;?&:(H'>G7F#+;D"(<310AB4/<);08%(?7G/$=!.3=;0*EA
@r6387
ATTTATCTGCTTGATCTTCAAATGTTGTATTNATTAAATCAATTGGATGGAATTGTTTANCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTANNGTCAACTAACTCTTCTGTTGA
+
)#)''*%#('+)!('*!&#"&#*'++""'+"!#%#&!()'$"*&#)**')&*"%"!'(')&(*%+&+*(&%%(&$'*"+#)$$%+!"+"(+)&'(&&)&*)(#!")*+$&+)!!$!"()!%$($!+''#)(!&#!%)!%&+"*&+%+'&*'
@r6388
GGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCNGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGNA
+
.16/64=/,DD84&8GE$@$H*988230%%!9+#2>(F:2@)@+"H>;'!H$8531-@F)18BA-#?CB"2!"$DB7=/6*?:G&CAA8H/$6<0#;:33*B!8B8,7G6-&%(?0:C7$#>%:G3$C4<8A8A&!!6;)115>""1E6&%'-:A5@0CFFF???-9(7B:)2%-B2%C*#H4C#(+#=*HE,6,"+A&2+:'4E"A*7&CF"@/"$F-F(!
@r6389
TAAAAAATCCCGAAACNGTTATGCAGGCTCTAACTATTAC
+
(+++*&#+)%)&#)%$%%$"%%)%("&#**&))$#)'"'+
@r6390
ANAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGA
+
%!F.?(&">F@G%#;0EA)=1)B;1-$B;,+%)D/1$9F"+,5(/;!A8H3,/+";6@A7A1!D+$"/6=F1#"8C?!H<B(5,4:E6A"'"&#(E2+/<A7/8>!H4H%B88F5@'8E,9#':2!A./@!6#%A6G.D4"%<C&)+,B."/,21:
@r6391
CTGCATCAGGATCATATCGNCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGA
+
(G-*</$"6'H3*4"E#$('A?16($!+*)B.==9&4$&+;&=085)9!,A:+2?E(=D!9C6'!&F+4//"%&HF&
@r6392
CATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGANTATTGGTTACGT
+
-$;/@F7"!=;%#*5-++5FC>A8G21>A91;8?9)<'6%A.!C>0HG9(/<
@r6393
GCACAGGAACTGAAGAATGCCANAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCGTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGNCGGATGCT
+
H55H75@=E)&<&:<A:!<E,'@+-!=?/%6=*&!'1#BF<+(ADC70B&)%*$H03DD&G,$@GF(#A,A<0@37B8.83'2B)+:6"'@8".:2F3&5)9@?E<8A9"&#65<=,:*#4-<HF$F:+.).*DA2D8*C##";>5&<FC'7G8D/9DE+HD0#!H"1E%E(>*9,'(;36E&133?<:=/%>3*!85,+A373>-9D<)()#&8$7A<-6B/,$B8H0*>7F4B.5,;4?>1/,%1)C:",@49@BG3$B6,%!##8.9G;?.?='<:-%7%2(E.DAB!4%.((-"G%5-C:$H;;A*11HGD/>3)1D!<FF3(C8/#),*@H5!-:7DH
@r6394
NAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCANTACAACATTTGAAGNTCAAGNAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTT
+
!1:9>C8;*-E=;$A,7)":!0,/#**C64B9,'-*GG.:/A7091%4AA/<D3+<7:;4"6C"7@84-A-;=E@DF*1==.5H:.7HHD9"CD0;+!@E(,=#D*D?&:?E8*.<;8G%8D,9.+6;D=@$&>4;$H""*$/'3G##5GH>'9<"*F.45$:)9989A->'339C#E/%'/!&,F?!&?5/'B)2!,EC4!F)3:6*6-=4F%3@3GB#8$/*+5'=0
@r6395
ACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGA
+
.7.7D"F&3+8"E>=+-;02/GHB'6%1';*>C>2;6"&C8E<
@r6396
GCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTAT
+
.&4$:A!,C(<%AF?@.3><%7F>/59E.(8C(3<8%!!992.=07,C8=H&#G?DE-#=D$6<="B(H6$8A;7<#):G07"55;%/3+A
@r6397
GCCGTGCCNGNATNTAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGNT
+
%'$('$$**%%#)"&)&$"%+)+&*#&#(('(%)($$#!+*"'+*(*'%($'!(&+#'"*$(*'"%$*##'"!%'
@r6398
NNAANTACTTANGATGCGGCNNNTNNGGATANTCCGNCANTANCNGTGNCNTNNCGANCNNTGACCANCNNGGTNANNGNCNNTGNCNCANNNNNNGNNTCNNNNCCGNNNNTATNCGNTNACGANNTNNTTGCNCCNNTAGNNTNNANNNCC
+
$#$#""$#!!!!#!"$$$$!$""$!$$!#$$!!#"!!!###$"$!#$!##$"$"!$!"$"$##"#$$##"#$#$""$$##$!!$!#!"$$"!!!#!!"$$""#$!"!#"#"!"$#$#"#!"#!!"$"$#$$"$#""#$#$#$$#"$$"$"#""
@r6399
TAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGG
+
,BC:C@>">;)FE?-+*$78<+6A&&C$!@"(?"4;-(;2@C0?1:6068?
@r6400
ATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTC
+
G)'F'/'$>(<&4,EFG?%F4A1A(4<"F-/F.?D""!'%65D<.+7)4'8<,/&004)6'.DB*D8DA)4',
@r6401
GGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAA
+
0!(+*$!*-%8D1&.$)5(0>4)"88AG=6E,F>/9E3A"=E1
@r6402
TGAGTATCCGTGAGAACGACGACGGCAGGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGNATGGTGTCACGCCGCCAGCGGTGCAGCACCTGNCCGCAGAAGTCACNGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCAGACGACGGAAACCACATACCGCTTCACGCAACTG
+
:<><*D5>7B!1+HD>4!5$G5!:2#>;3H$CB6)+/A=*;'D"..42B:5$@=5*,(7*99753,"57+B7?$C6>?,CA1GH8B%?.,5>7%!!G:@/?(@2@8G@09?::6*E>()D>;.F#<4.(H9?1A.4FE$>HA*;4-3;(4A$920%!#&4E/@&<.E;@7',1&7528(*3:=F%=G<#)'.7#4<+7%@8%74G,6206<;,F>;,4&B.'-?+-7%#EAFB+8G1C1"F4$%869=/3H+)CC%B>3*90!?-25<G"B1$D1<%1$CC0/:.$)E,8("'G)C/F.H("BC*-2.5F9&B)$6?3#(*#557A:%1
@r6403
TGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTG
+
4C/+0HG!1>645(5*&>.<23>%B95F?@+GBH##78E=<B=%"81F-4B43G23
@r6404
AGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACTTCCAATGACATATCGG
+
:%8/-'9,=+4&-;=(#*+E;CD,=2G=@,,,23+%:+&-$8B108#7<9,8%A@<',F>2FB"6<0+6+!47-4GCAF8E*=9)*-7:)-?7DBCH#H""
@r6405
GCCTCGTCCATTTTTTCGATGAACTCCNGCACGATCTCGTCAAAACTCGCCATGTACT
+
AE6@!H9"E5G=>.!FB/38+;?,DD4EB@11&!8:DH)'C61-!-7!0$0*BF).!9
@r6406
GCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCCCTCCGGTTAACGATTAAACCATGCAGGAGATTAA
+
&8HE6H799@:!99,AG1!"<#1-$)$H*5F#'#!A%)2?@.45,,F6&9.2'9'E8%3:$4,4F<7=1=D'6%!?1><(:;($$2..4)80?-E
@r6407
CCAGCCGGAATATNTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCG
+
++)*&%**##')&"(!)+#)+*+%(#''+&"$("&('$(!&"+%(%#&$!!#$(*"$))"#!'')#*''#%)
@r6408
ACCCGCAAGCGCGTTNGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGNGTCAGGTGACGCGTCGATATCATCTGCAATCGCGGNCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGG
+
@87E9>=;7F$C?4$5;9(4+012,GA5*HDGEF3*G51-6?";E6'5E'-*B!5F+9308;7F?7CG;$+D<+2DH./3$CH"#=39!$@(CAHD)'0!/%3=6644F'!9!=(AA6>HH"9F@%AH"#!"?/8+:-.!2=+;@7?)-%'#B>?H#8*)>HF9(E0G66D!C,G@C
@r6409
ACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCGGGACGGCATGACATCGCTGCGCGAAGATGCCGGTTATCGCGGCGGTGGCAGCGG
+
.,,#""@@/*+/0$>$?-,@.F"6C.-88D30618@02@60824:93;;;G;*@;;7(;@=D)=$89+&"?8)%5/&,((=D69G15A>4<%GD"<-F:8E,)"8&;8&!3B"0'A!E">((>?@40+@0&!C9+&0"97/2D>?&!B82(,1=&8-3*A*(#?8,:C:"+C<.99$',B!
@r6410
ATNGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTA
+
('!E?"B"4B>610:+?,6)%3@A3?548/2BA'2##;B'B@6F(<#(:
@r6411
GGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCG
+
FH>(861":$?FG9;'G6-/=*385(FA.=F/'E%95)FE30B/<8$5($,!&*".B*
@r6412
ACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGNTGATATATGGAAGAAGAATTTGAAGAGTTCGAAAAGCATGCTCNGGATGTGATGGAACAATACCAGGNCTATCCGNAT
+
D,:G79A;+@F?4>?<%3%"H2:G4B>HBAE/@>7.7=D=7#!;69&67-.0",-)1,F'-G*'F5?0*E:)28$+;3'63'$>06,A:+EG;!1%;H*?@6H:FG!>'+'4.33,F
@r6413
TTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGC
+
/!F"$5DE%BCF831#6#480+'7<49./7<(3$H,&!2'C5>78E<AHB!68G#4/B28(8E0E1
@r6414
GGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGNG
+
/D;=@6BD-'5F<!7E5020"4##BC:3(H,G>.H&/+:/?EB6%D):<?+
@r6415
GTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCGATCCAGTACA
+
F4=,/,0G=G<@$)!)?@/2AC*0(B7F48-)?,@:6H*G4<(2!+'#C622F843)A4.9<H9A(G/>,H><
@r6416
TTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTT
+
B(H?F-333+#91*(2D4%>/,1<47%>C'*!,DF7'1F0*13*/72,HA;0F50?97/>;(+A&35,5:"%!
@r6417
CCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCNNCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGT
+
(5H=2>/D#*B465EDAF28C=C6/6C*DG*1H9+1HC!13>2.=/,):';-59/H&13=$$<D7?3F65>,%B'0C3$)H/?C6"#EC)A">0-3-H"9*1HB$-A@'8EB<'%(0<33(':?&BF3;
@r6418
CATGAATANCTGNTTGCCCTGCGCCACAAACATCGGCGTTTCATCCCCGTTTGCCGGGTCAATAAATG
+
1$41>9D4.E2%8&42#;5H.=0:%#)6=9==6+'!<"/-;$8B38FA=)5EG*>19G8AC6%25;'5
@r6419
TTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTG
+
CAC=4DE$"!:G$,%"/'2G3E/$/0+53!@@&@47@==&G23#+8D01948C)-6)6>5&$F%-C&36$"602H*>+;&2B2H.,"*81'=/#E'/"'%@:C/>
@r6420
GAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGNTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGA
+
=H;!2G<D<6(1$#EE#,<+@)+7D5H'',<1;60(3H!(71'70):<'A!F129%)0954&%HH+&!,7&33H5-$=@E?2,<<'>$2(5).(-=9$&@E.36:44*BC1?/:;99176+4"G(;=#5"F;97A,.)>8=B.9"0/CEB;/)6!,0C0E9DA4-3@6"(
@r6421
GTGCTGCACCGCTGGCGGCNNGACACCATTCACCGTGCCACTCTGTTCGCCGTCAA
+
@G<9/)*149H+<=+93CA+B42/5/3GB<C>%E0H8-:;>B1CD&+1&*1C3H-#
@r6422
NTTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATNTATCAACAGGA
+
"EC.280,6)<);HG2."($C-DB(,72"%.B4@$/313"D/+H><=3;-,BF'EE.#>E4$&63!D433$H*H%@-8;H9&*#,8F)&;F57!8.0,!<0,16<?95404!76
@r6423
TAAATCGTCNGAAACGAANGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCNGCTAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCG
+
')&*()"('"%&(#$'&#($((+)'!+)%"&%(&!(%#%'(("$!!%$$"("((#(%+*&#!&#+#!'($)'#&&)%*#*!$$)#!&+*+*("&+!#&(!$'+***$#"*"')*)&$%+#%%'%))%$'%'"*+"%#'('++&$"%
@r6424
CTAGATGCTGATATATTTTAGGGGTGATAAAATTAACTGCTTAACTGTCAATGTAATA
+
80+;,F84@%%'E2<75H772+)(3)D:+9A;A27=B?E$3(G!07->-;!%&602"C
@r6425
GAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCNGTGGGTCGACAGAATCCATGNCGACA
+
!$C)$-@*#;"0-F8:&,;!%:7/5":FD<=:!EHEED?*-H<.1$8'A:19<;6GF,6%D"DC=52A5;<C*3,A6CG?1!.!-,3B?1F:,25=A)
@r6426
GGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATNTCACCGGGCGGCGCTTNGAGCACGGTGTGACGGACTGTTACNCACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGNCTTTCATCGTGAGGATGACTGGTGGCGTANCGGCCAGAATCTCTAT
+
6+E7FF0A-8%?#*,1.:1C/6H3+3,/2=:/<:7>!'F64"@=$DG%416<5C9>A9C0)#F,F*!8HA-8H<D+48&7*':C1<0,*HD4"G'.=-C&9+D@HH!45:'+&,HE;,8C;8/,-<8;$8('05*F;=D,E29=7<(*A'C:;#*2<*83'*E++-(;HE
@r6427
AAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATC
+
+<6=22<+?,"2GB4=G%)#D=4?7*A:G-84FF(B=0F#8>9
@r6428
GGTGNACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAG
+
$+?=</D(@+E;#8F!)-.9'*%<;0,")<&/!6G*"@($,+@",*!B:.BA8$0-
@r6429
GTACTTTATGGGGCGGCGAAANTTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCTCCGCGTGGTGACGTTACCTTCAAAAACGCGCTTAAGA
+
B"G;G**2#'6+;E<6&*A-9:4,F+GG8@D@3;4$2C/H:$'=68.,>%<B&6#7H7:8$BA@.9<D:#8/>7E>G0)'GB@,&6'7@6?-#HHD*'$,@#G*@:/CE('!9:3HH3&+0
@r6430
AACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGNAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGG
+
8?6$:>8:FA$F9AD3C5H?4%:/9+<>;F%-3>-4-3!FH963320@)>!-0,C3B6!?&.;)DD1:F9060E001:D/'.%
@r6431
ACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCAAATCCTACNATGC
+
D.&%G2$>C131!C$A()%.193?1F):F9<!"DE;@9:*)1'@*6',>4E@6D1
@r6432
TTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCNTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCT
+
38AB'BF07&:*E,>'9=A*1,198?)=>?20>)"-1>()=8E$EAD@9=2=(,+6(4C!2'1"+@1@B;A%!'?%/H3)7)>!8A/D,3C0(,B/;:=7C3:B>$?HFDC.F2=
@r6433
TAAAAANTTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTANGTTAATCTCAGCAAATTAAGCGA
+
H3(/BA(&H%@'&)?+<G7E:H%<$4:2;D23$*@6,=H),8>6B+6+:@GF)4*-*)G6%!+)H3=3.):%<7+C+=9#G92H
@r6434
CATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCGG
+
1GDEHF!'*ADF8H=0;2#'A63;0CD?9<5AG5%&#+GA4+6B!DE-F;%'#@=4,!/7GC4/-'2<+()H,5,C9;-6<,,(@/6?F)&5!BG6?=@H7:;&E!.&&=$H#/AE.1?=@6*"A(DCGD>259C;D;61'2DB0>2:BA85HB-9"1B,049)+7+
@r6435
CACTGACGGCGCTGGCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGANATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACNTTGGATCCACGCCGGCCGGTGAGNATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGC
+
(*?.C%%(F%G178F'AG;*H<1E+0<74<=46F/*=*5?=1#$G'$>4!H='D-B!$,4H:8E.5?-)C<)AE>9*7A:B')$)?$.<@-7&":C,&8-E25(-:10;B5>@H:*.7,:0@"1+.4".8>%)08-6/5)*"D+A"CA4';D'34)0CD@(.-F!EA%=B$."H$B3,H5$=,2&7#034(+)B1-@?"/0%=&7E+$?#,8*B'D-#>G($%B1E@9"B;6H%+C(%E<F*H=
@r6436
CGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATNGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGT
+
FED0);2?F485?@@"">&B7;+:<G8&</);CC,#400&(!E(G',B6,A,DG/H?"5B=,B7A2<'>&(&@57?H&F4A:$3*B
@r6437
AGCCAAAATTTGTGGCGGCGCAGAAAAAGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCT
+
*=$:)139'BAC>&">8</G,/2*8G/GF7*C3BB&*<%+328&-3D+%D5;!<)1*6B0&$,41<',2144
@r6438
ACNTCTNGTANCNGNTNNGGANNGCCGGGNGGGACGTCANCACGTCCGGGTTAACGGCGCAGTTACAGGAGACTCTGCCTGATGGCGCTGTATTTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGA
+
)*&!*)"'!(&&!&!'(!#&)$!')%*#%!+'(#$(*(%*!#!#"(*"*%)*+)+!(!&)""*!!+)&(()!!**'&!+(*!)(!!!!$"&**')$!%!!&*)+'#!!&%)(%%'*"%$+$'#""##&+"'&!"$#&%$!*'##&"#%*+#)!(%"%+(((!+&!#($%"#!#
@r6439
TCTGGTTTTCTGATGTCCGTTATCAGCTCCCTCCGACCACGCCAGCATATCGAG
+
0>7/)289)82:DHF'-HF8$"D'-(E.G!!6,A@F74H?//AD3#(6*AGA,-
@r6440
TGTCGCGTATCCANCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGNAACCCGCCAGCGGTCGTGCTGTATTNTCTCAGGAACAGGATGGAATTAAG
+
?'/;9+9F-5FH>(@?&F(%4.>$-$F9"A6%D4'@?F;CF9.>-E1;E8F'3=?+?():6>*=2D8'6!8(=*;<FH#BE5"8CGA>4,&6EC0F$*B.D+?,.D
@r6441
GTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTTATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGA
+
;%2$#/8>6)&1&F+=DB)';-@B9D13(:G5(,=<10.)>F306B=./9&@G5=45A#+-?/GD+2>E301&@A><04=$F>.,=AF&47>%3$$,G;8$:-@EB""A2!$$#(D
@r6442
GGGATTTTCACCACGTCAATNGGGTAACGGTTTTTCCCAGCCACACGCTGCATG
+
1?>/,$&*D&=))?*$A'>9EB6(?-6,=,"-4(GG(0(.+H=!9B-3"0:A=!
@r6443
CNNNNTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACNAAACACAAGGAGGTCAGACCAGATTNAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATT
+
#!#%&(+$&#%&$**$!(+*(*"%('*$!$#)#))$%"$&)&)$*(+(&''$#++*"!)"**"'##'%&!'!)!#&'"(##+##*)&)+))$$%))!!&%)'#))$!%"$+()(*#+&$"%%+#!*&*+((&%!*!*''&+''#!+#**)((&+$&''%*$+$#*+)&*
@r6444
TAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGAAAAGTGTTCGACGNTGA
+
?;E;4#7-$8.C5-=0>>9+20'<"0@G01.A>>@,+1B4C$@6<,(D2DG5(BFF,E#!B.:FE3(>#G>
@r6445
TACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCGNCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGACACAA
+
/G7E8:H.6#9-E@C<*:?A/&1==.>E?'E<+'A>G/81H8D"H:'39D;@<E/:HB+=15&5=7-@)9?@;-;FB*'A?8=?D:42>2E?>):>57#?//'20B77=/6&&=%D6C@6,1?+"#B!#DG4;-(8?<AD!"'>D)>E:.2+6:D;B.<3@=%4+&!".0+AD39@C7-/?3B:0+9-'9.>77=6FC+.64,:"BB!)!-(;6"://#&+.D@E,/#81D7D:!73C*268959&7$4.,C+EB)EB!:?5)HF:1*4/:;?4H6.
@r6446
GCCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGCATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGTTGGCCTTTTGAAGAGGATCAGA
+
%FF/57%757)13"'!3.1?+H/,FC9&E#DDD??E6;.6&6"A<'76*>=;#++"4)7=4.,,27G6<6)9!AB41##0E7#-;1*D':H*$-3F%544
@r6447
CCAANCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCANAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATNCTGGCAATATGCGGGAGATTACGCAGC
+
76414?B!=&><+<)*H1.-BD4,'-=5.&5;=B8(,("HF)*@%0!#;B"D5>5(<'8-/.$7D,EG5=B7F*&&%H$&BA0D7GA2+6*-=FEB&'.53$2DA
@r6448
GCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAA
+
?=.4<3.6-8)EEC=!5;D;/)E48&70G8!@9HA28(19'?;=<$&-&:$,?F'0E?+(5D?&C9-H95*#(+":"***
@r6449
AGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAATACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAA
+
=.*;!=5B8/67>6'6#$,A<3<**C">!-(,+3#4*DG'/H=FA=404H89B)!33#?6@&@7E=&>79$/<#?9?%E)*B4-#!.+9;:*5C"C<'5F4;7'03@G1*&0G&E<$0-"E&%E$<"-9%64"%AA)7!4,#>?2)G.2>835;59$8A#*'4;,199
@r6450
GCCCGGCTTCATCCGGATTCTCTGANCCCACCGTGTTCACCACCACCGTGGT
+
#D=.EBA.*/)2.=B.$EFF/#D2CAAH):-A0/65%0F6C23*)A9B<!"A
@r6451
ATAAGTTCCGCTGNGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGNTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCCTCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGGCTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCNACGGGGCTGTATCAGGTGCCGTTGTCANCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACT
+
9E/@AA4$5@?E#'DC27F50+<A=%5HF:8-++"BF*?"HFB-!5B@0/<?D)"D@7B=3.>$'+G:(F=F6)<3=A*?G%/G'F*!,B2-2E03%1C<DF!;/!F#)C*H?-78948D1B'?HD,.'F)>:+@&C7H@D,/2:.5+<.)CH$B5+39)*C1F>5+*F"#C-"+:(@3EB:6374?EB$&4'?G"462$;&6':':C)/F:$=%-(A30@;81"B4-*'#E72GAH9=E6:4*>D'-G&=0(!C(*5:2!!G+-+7/;2D5?0)2C:2C.##%,#994?&4B11C#,/0(GH1,HF8%$84-H,!.HA@8402"+D;+7AE"05F2*#/AA':(#7&C065-G4H>%HAD4EE6+>)=)!?FCB6,*7'40<<F.<!=(=6/'!E&8;E,68!!*2:.
@r6452
ACTAACCCCNTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGA
+
999&;7/.<98?FE:86@$/5<59$)/$8,&25$:1?@999&H;'7*G,)%+H'-4+B6&D251(GF'.C/
@r6453
CATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCA
+
)*+%#''#$$+"'+#$((#"&)")+%)(#++'*("&*(()$'!+""'"$&"'+&*(%$)#!&+$(#(&*$)
@r6454
CGTTTGTAATGTCCGCTCCGGCACATAGCAGTNCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAANATGTAAAATCGGTAGCAACTGGAAATCATTCTACACCCGCACTATCGGAAG
+
0B>-;'=4<!+44%#E@'A'>#C;:=)@,'<.7<'@%G%;171DA&6='&0)//&'=4E29<(D.2E<*9+-@G26F;9F*5CH0DE2;$;8(#'*;@(>;.C/4HD/$3-/)3GC2<:A'8$5B258G&((=8G826$4>)<0E?.$8G*'
@r6455
TCATAAAGTTCTCGGGATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGN
+
@,:5&4//(2-;+):=B%@,D%-%<)-9A"0CD,-<DDA,'=#C6.!'+G)G)%B@;2%83")E9>%:-$9/
@r6456
GCTTACGAACGGCTGCAGACGCCGCTGGAAANGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCAATGANAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGCTGGCGGCGGCGAAAAAGGATTATGAAGCGAC
+
@H6D+E!+$3,=).-1!<.=)83@34:,,1>8<.;:B3(?$"GC<?7(@>$$/%9@'013<((5!EG87@#.D"#C41&#2<E&21G'F,?D%9%*A1%=9.3-3916!>&('=8*=**(;9:="#&';;-#:1E;?&HG8:"
@r6457
TAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAG
+
$*G/>76+H?/)<$DG*:5:4!B1($G8,5"&AF$B'HD21C5-4=.7A&6;(225D*H
@r6458
AGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACC
+
'HH$0?'C#5G,/0)H91;B>@--)2!DF?:-)-F,+@(/FC5A.)B(H'-
@r6459
TGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCNTGACGGGCGGTATATTTCGTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATA
+
B;9B*)2E#"/#B22H1#5H;A>&.%5(#F6*%8?;'AH=-E&0%43.&11=A@!63?9@*#;&<G.9$2+#3.(1)-/1$)1-.6'41.4/G-83%16H3%8>GE>&9%>4,%9//)C2B<*4
@r6460
TACAACCAATAAATGTTGAAATGAAGTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAANATAAA
+
%1'6B2#>58?0:CB!0A9802A&E.D.1/&'F8(<3=9G6'5G?3&<E:8:"0&9:##9%B2,H.$%?B0&&7E8/*:.A)D="'1ED#
@r6461
GGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAANCCGCNGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCNTAATCAAGCTGGGT
+
=EH?4"HE8&0"6+33;1/4)5+F>9G-16<!&.=3*???)%*@<?;%<.D'>&BDC820?81"C%$@DD5B0G::,(;@D%=@CDGE7+#
@r6462
ACAACGTGATAGCAAAACACCGCTCCGGAAAGAAGCGGCCTGACATGAAAATGTCCTACTTCCACNCCCTGCTTG
+
+"!#(%(%++*+"#)#)"&***&##'+)"%*%)!'"!)"")(%"$!*+'))%%"'"%'+**#+!+!!+*!"))**
@r6463
GTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACAT
+
B5-39&+*"A43H"3=DG)<G<D=/$@--3,,,&"D7><B9>%-*39,@&G1<)0*>-'!A(-%@F$.$(2*.*@E0B.,
@r6464
ATACCCGTCCTCGCTGACGTAATATCGCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTC
+
==;5F$AE'#*:3"!>!:?@01..#*1.47!:!3&:)EB':!!GAB/8:C*/B!6.'E:A+5+)AEH!1E1")
@r6465
TACCCGGCGGGCGCGCCTCGTTNATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGACACCATTGAGAGTGAGCTGGATACGCAGTCAG
+
4@<>3%6F>F7/+G@$=><C$@82&@2=+)FDB2%%@BB%@"D&+6B45E?E&C.)"3</-H:861GF@!!?7?%?;H*DAH3:!%9E(-)6(":#'1@"/@G"?G3<&H")E0?.(?207"".@%!=<&8*=(EC91#:G,F5);;'.(D<.$&;3)7+:F+B<1$G2"340F%C!G%E=4$!(!51A,@*";:
@r6466
GTACTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGAC
+
GB2*5":9,3-&D!;@)$'++D5=/"0%-6/'5;D#'?C@3/@GE47:2-,8:(/!
@r6467
TTGCTTTCAATCTGTTTGTGGTATNCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGNATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCNTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTNTGTGGCAGTTGTAGTCCTGAACGA
+
H>&>1*6(966.D8!"@&:CG+7)AA6#H*A6HG&+C,)+52A*1?/EG53"4%<E2F'HC<(+F&*=2;%%$/?25A7!G&A'.:9'65<8H<).;49F7=%DGE=%<42?!GG2%7D5.7A<.)B$*0!$E&>)>H1>""?,$:>G$E10705&'1"FD%-F2A5GBA%7!+;/>@=E)0).CB9DB,51=7A"!25E&?+'G&)9DH8@6@9&9=2'@%>.?A/(,(G:')<5%C4C1";"59@<$5C+H9==%*?2$*,./
@r6468
GAGCATCAATATGCAATGCTGTTGGGATGGCAATTNTTACGCCTGTTTTGCTTTGCNCGACANAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGA
+
:&AC;BD%-#6.>F?C!-1>:,@=-!#/8?!B6@/@;2-0E)()<&,/!*1@$#D<5BBB)9B(1@"*7(%!H--$#8G,G*9%&:H2>%C-;H&!(&%69.%>535.H**@07C/4$H&>6%+@5H6%6/+G;5&<%60GE#F6!&F3@&7>+/01:)FF;1>!891$E4ED62((6:9!'B5@
@r6469
NGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATG
+
!,C)1C&C0'2E7)/-(2+59H%"F/G,2?/8F#-AH:H."F
@r6470
NTTNNNAANCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGTAAGCTGACCGCTAAAA
+
$*#%&")'$*''&+"&!%$+(%%**&$'*&(()%#''%%&+$#$#("+"*%)#"++(#"*$)+'*"$+#)#)*!)%#&&#&*#)"+(("%&
@r6471
GGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATG
+
H<GD@/E;B-,&!8:%G(,-B(;"2G44,)A//"?+8&?BA
@r6472
ATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTNTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGCAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCT
+
A+?0(4..7&(HC3=16"05DD#;GB;E*GH20(A*"E;>:1H-D>"050%D?%*82)+#*<7H+?)/:#@12+,;'G>@3C90/4<"2=H>@E@*0820C0&B:<<:@,.<3A=E?F'D&4/,6(862.5:'47,*2?;::$8?=<!'$8D/021E'BDC'?011%&<3?6%'DE'&92&BD:F!(&4,>A:E@.
@r6473
ANGAAAGCGTANCTAAATTTCATTCNCCAAAAAGCCCGATGATGAGCGACTCACCGCGGCCCACGGCTCCTGACTCTCTTTCCGGTACTGATGGGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAGCTCAGCCAGAACGACAAACAANAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGAAAATACCGTGGGGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTTCTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGT
+
$"%#+)+(&$#&")&((#)%$(#$)!"++%"$(*+&$*&)!)&%%&&+(%)(*))$+')!!&"%)'#)'&#"'&**!+#$')&+#!'"'+!++'*#+'*+(*#$((**#""+(((&!+)'#'*%&!"&%!(&&&$+)%&(%"#)""%!#%)%*$!%'&"*'!"!+&(""(!!%$&&&(%'+*"++%%#+#'""$)$**"&#+*'(&&""$+')%!#+$*#')''&&'%"!$&)%+#&')("'**(#*&')%#()#(&%$*'&##"'$+)%'$&%&(++')"+'*)"(&&+&'*!*+*""*!$!%%(!''+"("$(*#)$!
@r6474
ATCAGGGCGAGATGCTCAATGCGCTGNAGGGCTGACAGTTCAG
+
0.-1B58!(E607!,=2@B$;5"H,)-DF!F;7,>+''8+5"@
@r6475
NCNNNNGCGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTNATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCATT
+
&&"$!'#!('+%)+%")!%(&(('!*'++!(%"#""($&(+&#&&)&$"!%%$&()*&#&&(%(*&"$(""+$!#&$())*)!%')%*%%+&%&#%"$(%&*"'&(&('++%((*#)+$#$(!)!%%
@r6476
CCATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAANTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTC
+
-"1<)!2E1D(7,.@,)-5='364E-C764&#6);,=G"0)5;,-H2H73BE7*)1E6'%&"(,'B#4D(/*ED:/?>:&>"5),D!B'B+</@31#E;/B3;
@r6477
GCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGAGGCAGCGGATTTGGAGGGCAGTTGCGGTC
+
(@5$*55%-C23B:8-"4?>58,-E9;!1$,-8/1F$5DE?54<A,6EG=09@0-<1.2!(+@%0<7$+?<8DB9DG9>B@A52@82%<.FC<F=57,C;D)A,.7='BC/A=A*,"H:3HF.09=0C('+;$C(?1$*=C$75=";7/B4::3,7189!C$G=33>
@r6478
NANGAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCACGGNCGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCATAGA
+
'#%#**$+&(#&(&)'%$!(*(&)++")+)"!!(%%"'&))"""%+*(((+$#$*)"%"$*(*!&!*#$'"%*#(('$)($+$!&&#!)*'$!)'&&!'$%(*"(!*#%+($"!$"&'("+(**('&&&**#
@r6479
GCGTGCTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCG
+
E&<.;*C4E.4!?=@$6"$"/$4H:&&9,5$H?)AFH-(4!1F'&>71B5:.F='DH.E-7,".C".
@r6480
AGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTA
+
<6A9-?)D,>&(H&/EFA'+5C4#,<C499CH/G/7)!E9.F)-9985FC.G?;/0'>HB$,'33;<C#E./.180.C:)B&13>:;:/->1?1"58+E@,762H?%*"BCE400/3@2A:GG+
@r6481
AATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTA
+
4#%!!,E9.8A6D/+F;7DH<&<?79CDH7<*2'3@?3D1;D'06G?(@*DFC&+A'0G;&;139&</DCCB/00A1?'*=#'-"
@r6482
GTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAANCGAATCCCATCTCGGCAANGAGCT
+
+"(&&"#(+'$'!'(%!&&+'%&+%+$"&)"$*%+&#*!$&((!&!*!&!(!*%)!$"'&#$#&"((((!+%"$**!$#+$(&$*+'%#%&&!*""*#)*%()%$&*&*#$)$%$)+(#
@r6483
GAGGTGTGGTGAATATCATCGTGTNCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCT
+
?;4>%*A19G-$2+C,1E'*/!"-%'B8=11+#$E>?DD=">E!BE!'0F#H?0'C&AB*,1B8FE@29F(A0=F<479
@r6484
CATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCG
+
C4>D=5+F/,6.H"<@<5%7B#%&/H*G2-7*)3FC;CA<*<.%#)44+-!FA<>DC%/='4?-*%A.9."*.)*+<-!=
@r6485
NCAGTCAGCGATGGATTTTATACTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCG
+
%+!&+$#%!!$"#%##"()'!("(''"$(""!&)$"*!%$'%***%$*)!'''+(&$$$)%"
@r6486
TGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGANC
+
7%<2D7.9)E@)"1?E*6E69:0&3-1%.+*.26'8*@G9C<&,*>:3E)/E@17?34)F(@7;G!*?C8H5+G(.BB/4B
@r6487
CAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCAAGCAGAACATCATNAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCANGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCNTTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAANTGANTCCGTGGGCCAGGT
+
?#,"#9+<7=.&?*4EF!)H.D?A8$:6":<7>92@B.A$,?(DH/G$-D:+&/%1<(04;9:@.;$58*4142E*=G"&/%;;:H=-!!7C!9$B<B!0C+",,?HB$9$".E15(.$-,=GB>.+2A94+0"8>H@";8%@)+@"*H=9/E,*5')*7DA99(-F(2+F%B5F*B*;6*>,*;!E.?D/.GF,EC>A1#E4)<!?HH>=2E<F.H@,!(F9!.8:F#B-==6<;9A0=.H1AC-?%;$!$!E&G6##G.91)$@E#9H4@98694));'/F/D0/:"@<@=,60+23=!3'0"@?19H$B)A6H-46:0"81$3
@r6488
CGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTAC
+
C&:,9&8)>G#>*299%F2EE*C/(.31<)=,=839(@830'+A+G*G%9"?A$>'C3*4@'(5+FE,#272@;
@r6489
ATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTNTTCTGAGNCATAGCTCTGATATCCAANTGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAANCTTGGCTGTATAGTCAACTAACTCTTCTGTCGANGTGATATNTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCANGAACTATNTTATTGTTATATTGTATCATGC
+
(?D,A!3"F,#8(*6F8?0G;B:HE2B):)%36',9"<:G-B">"E>.>,=/@)DD'%CD%23.<0%1C3"@1(DD?%+H<0F*&1&847#D0C@#88$?D(6!F$94!B&?H"A4)0%5/@%=%?7.',##CE&,9<#,A9,;18#2A.:8(<!<A5,**?$G*=;,:.D$-/3$4/.F.';'?-$!;(B@A934C'"/3-<?>2'C6927*;$(,%50F<FE!3/><"?@'&"'52<,3=:$A,GH72<<9H#($9<G4>%@2<5$/4!?/?#E&?;19:.!6B.#)G2A3<0)(%6(@"G3:?'D0&6264'GA;&87!&/!9BG6-6$2-'?D;-H-@)*=.5-<@5HCFH
@r6490
GCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCC
+
G@9G#,127.?25=G,#6B#;G+5!2)<18?D96=,$!$;!)!FC!9A6H<%DG#,0.:+<2--G;9.FFB-5#ED9=9<@&=H1C&)8*<$0?*@@:'6#:D08=)?!B5@#8
@r6491
CCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGNGACATCACTCCGGTTAACG
+
3&E#=<$$/8/@+?4'/D<#9*8+D9#76E=*73/#'@G('6)(?E47H!:HE-?'9G.06@'H/,8$/B<D
@r6492
AATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGNGGCATGTTCGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAANGAGGGAA
+
8$5D;1)3>1?E3<@C68:===>)4-A*(>@.450+5!@>.)-6,@,:44-4#**:'B*?,>)7>%'7:7216E5>97(??7?2C(F1A,#'!7"+2&B8?)AA8B7&155H!6%6"&0H;'F!+3=H:>B1%2B>+."D>#D%(7(2G4G4;H5?:)%?45#9+=<&<>D<D:@4&G>006363#5FC=7,19$+AGD/G-E/G:;!";D"94+&.)1,&<A#G66858E6$91<3(03+8*3(2.47650=14F>02,.*2-3E+?8<:3F<%AH-C"FG;E,/E:EB#EH$?FED"3-#1:*+21>3968F14=!)>G;/<-"D=%>6?-F75H9>4F7EHE#=,5
@r6493
CGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATT
+
,H6G)8"5$$/A,(),@"(A2$0HA-!1$@A4C!'09/"$AD502A8'9@+:+2A3F-&;B@"!12G!/@,4G>C?'B$7$$F7;,F8=;,.A6476*-<$-B+;?1A;:H.?@/;E%5F(C'40$FH:%+8+"(5!(')$EED+#H:!H5#GG'%#:&B99
@r6494
CTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTAGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTG
+
HF1)?4A'?&,"?%!<29A;A0/C5:%,D">7*/+H><G5?<C<:C<FA6<!8A@">55B&8EH7G7F)%>EA3@,25B:3-:2"$6:"0=#1+4H#50?5#>+(#'&.E5.HA(%(;7%8:205>?H<"2.!,(,&!9H$
@r6495
TCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTT
+
/4=7#&6057%A=0@3D+0:>7FB@'6987:%#6+G@>''.20-9*%EAC6%;#&H6%;=C=/8024%H?&+G,&CB!(/&BB;0A$>4+*85"F>H>-A9/F,@&3&F.C'$?
@r6496
CNTGGTCTGATTATTGGNAATCTNATCTTCCCTNCNGNGNGAGGGCGATTTTTTATCTGTGNGGATATGAACAGATGTCAAACATCAAAAAATNCATCATTNATTACGACTGGCAAGCATCAATAGNAATTGAAATCGACCATTACGTAATGACAGAGGAAAAACTTCACCA
+
*"*)%%$'"%(''''&$"*'%*%#&)!&!)%&)!$$&!)(+%$*+!$$+)!)#&($(*'%")()$+(%!#'%'($'*&+"#&'!&)*!#$)''(&*#+"(()#!&#!)"&)'('$%"%%#"$"!*!*#"+(()(*$"#$$*##'$()!#&"$$)+#)#$"&%(%)#!%(!!'
@r6497
AGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCACCGGCGTTTTCCGGAACTGGAAAACCGACATG
+
.;/1$@;GF20>.F'&?/',1*;!%:7G0/71(:?1@%BEAF;!A-?GGG,H.,@3:B5>'5+$5="B>?1A;H8&B
@r6498
CAGTAAATTGCGNCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGTTACGTCCTGA
+
03.G=C"DGE?8"%&66<5BA:G%A";29+D#FB(,-.:.F9&F8:(EG1'&+);BGC#092=9BE<!F0+.H*9@!-07,8$//25D7>(&@7D$77)
@r6499
AAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCG
+
CA83+%.2C8F'$EB@7H!3HCC<)8BFF#7-A)<&;*>64BB<G*<%7>#B/7556!8B99,170F@3H=@A&6')%)+%C))H)69?C..)C51#D'"5%7!"$.H@2(23!7*4+88F4E<6!*#,<#/9"H7==#A*@?B,<.=E04<$:#(34$&-B09;5%<D>2@FAA$
@r6500
TTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCANGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTGCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAAC
+
?&@)+;;,88$@C@1/F,#%96208$@=*6#)A?9F%E9(%-:A!>1$E$,0F?948A9=#=,"@(%3A-3*#3*G'45+<"(GF(9BF=CC)&;+:302E**>.*>'C";"5F(':>1DCA5#9:1+C'>8*">?&("?H?&:G$%"&'%2G%"10B'E,(3#+=$$=H?,+:-+?HGH0$@1F7A*/HH'.G7)<G,)%"?(=HB@9<.F-6**+$F!=>:<25*?AB>4(?GB8C/&6+.3H/C'95F!$-#7-C$+!7;@.8;%"G=A%>'H%%$>*8
@r6501
NGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATT
+
"1;!0)5F0;,#3GF3/C:$(+9+''>-:.80=(E)6A?7%<F91*09&E$27
@r6502
GNANANTGATGCTGCNGCCGCCCAGGCGGGCGGGACCGGCTGCACG
+
*%((%""$$+""!)+"+(+%#$&+"**+'!*&$%)#&'("($(+#%
@r6503
CCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTATGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCT
+
(1&1=$23C,CB)2:7GD3/9!1>/2F("6@==;+.G?,"F,5./!EDC6&?352%/.$;=6>7&*>818H#C<<$>7!;D=*%741,9E=-19?B"C#<C8)-;7@!1?)*(
@r6504
TTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATANTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTA
+
(+&*#+'()#'$)!%+$*#%)'+##%+**!$"$)(*)""&%$%+(*$*))+$$&#*!)$)*+#$#)"#&#'*!)!*#(%!
@r6505
ATGCCTGTTCTGAAGCCATTTATGGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGC
+
);@!159:5H40A17-AAF#(HF=#CBF-%%C1,!.%F/H9#&:)49A,.F9D:7'D0!)01('??,$69,;
@r6506
GAGGGTGATCGGAGTAATCAGTAAATNGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGGCGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTANTCC
+
=?*:/,3(#4(,/2?:A&4!#B:/'-*=4!G3H-G$>"%=?2B#?C*2+,A79(2F/=D1(>!!A2;6>,H*:$A@78#4B?4:!:H;2$C88*(+.!/$)>/+/3)&@H!B+?$B$@=5$GC,>=*1?9)H,!"4>?&//=69!G?9H%1@E"*B3C
@r6507
TACTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGNGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTT
+
$!G(F1&43."G/2%7,&.76.C<'6,:1"'>2:;!8E-+1913!+B1<.26#%1)2B#</8%+4%19143<3*9>9@B$0GB8
@r6508
CCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTT
+
2/G9%6!73$:;E):@$3=5)?@#!(-#7*5E(#1#?9&E*2.<5-?"&,D$-&E15(6G"0H+!G#:2'5<#518-6&)D>F&E$&8G;*6G>0@8)
@r6509
CTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATNTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGC
+
5H>#,;"&B,D%=&:#B'+G()?A:7D;0&-=13&+)E3>D.:',2E#"G%?1G%'177.8(?"01:6*/1>GDD,>EC4"
@r6510
CTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGTGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATA
+
.B4#B;")(5F%&=9'!5&>#"G91&;&<(H>+>/(;:.?$F&"DF.987*;.'>;)B#1*G#*B.,1/#!?=C=&CE#$;/2<5+47BF':GF"G.0$,&G=99;'5+6$*,20D&F9F8DB>CG>-,,>9FH4-B/E-B@>A=(()#"H)$F+4G1('G,:*G'/2#0:88!(/C6/A##&66;$6:&8$@?@!(G76A=6=)@<.BG3HG4%=:G/'
@r6511
NAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTG
+
+#%()+'$*(%&&+"*)#%))(("*#*"'"''$+%$!)%#($#$!%*!+)"%%%
@r6512
ACTTTCAGATAACACATCGAATACGTTGTCCTGACGCTGACAGTACGCTTACTTCC
+
3!,@%(;@#4!;;=*:<C:&H6(BA-6?F&.,+5#6&8-%,C5,E!<+6@$G835C
@r6513
GAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTACATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATNAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCA
+
H%$<<!-+:8'C,A34"5B/5$.!++>C4>A22.1&7#"B/5);+/84<:8"4"$-/.,2#&FHB:.9??#=+4:4A828%8)91+E8E5&*3"@;',#6$-$*#@*;5$-%">D9-:(90:*".B+8-?=961=,3E4;(<9,0(-#,?;<:.E.@57/."%H/56B@=CC82?6:"4('?$=:A&96)5#@*(B/C5!/
@r6514
CCTGCCGTTAANCGTCGCCGCTGAANGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCG
+
6;5@:6'66D/+"1>(D!A5,(&0:*@13@06+C<C7H>6*&=<),*+@2,;>7=/'0+(>44
@r6515
CTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAA
+
2#7/)2#.2D-)</4$'H.896;1*@:-6<=6+73A>,7,@&;?"A;.3+AB&-%A-.1<-83#:G'A(=D1(;$
@r6516
TGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTANAACATCAGGGTNACTCATAGAAATGGTGCTATTAAGCATAT
+
?D;#9D$#8/@E-;+B=D@/D'2&D!8:76DE.A%5B+!3'C8CE#??4833G+G>'/E'*0#5"<),=?#+5;&+?-G9%7?04:--@9::!G+3HC8F;E#!#1;F&)D5)E'1:.A3')?H@/DG4@"+?(&>5&8=)@#>$#-C)!,$=F(
@r6517
AGAAACCTCGTTGCTGGCAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGNTACATCAACTGCACCTTATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATNTGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATAGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATG
+
7E!E12G>C.(;6:8@",1C<8A0*1;+:+7/'B+=D$?&0A?,:A,3%2!AF8)2,!62F6<GF?0E1'+(%<(/+'"0=;DB;9,6%+,C!)$1@B*+<$+D42A:=/*):H=F$B!:"!9,%"@157@'&/>#B7E+CF-6G=%"E?)E!>8/'A!;B"31<AH@7/A019&2,(<21EB->H>H#H(6).=9?"HE83D<H?/6>5=)H:G-.'9;&E)2F>/?F<1-F9$C1!#:A>!F7189);!7E'!F(A3&A>F+;38GB!#?)C+*-"A3>'/,$6.A,>G;-G!5=8<
@r6518
GGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAACAGCACTGGCTAACCAGGCTCGCNGACTCTTCACGATTATCGA
+
H/4=,DF3/"?9.>39?9)0#"#6D1@.:E@4*0G3>&;E6&9("61+E)%,G;C6++.#!);(@!H(=:25A=#:-)B1H,#+
@r6519
GTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAG
+
)D<)-H$3(3D'6+AC<F14#F@+$;-G/),4)"#*H%A5"+GH8<4/+D
@r6520
GCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCNGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAG
+
5?5>!?(.198*HB?G!=3*2C@47*C:(#@2=D;G8C'9:5(2E6(;#"+,-;"&F5!;6E=3H5%C"-@21,1E3#-:E;A2(97/&)'%7"
@r6521
NGTAACCNTNCACTNCCTNTAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTNTTTTCCAATAATTGGG
+
&)"'!%*"&"&$'#")'"$()+"'(&%!!*(#$&(*$$&$#*+&)+%"'*&)$$!#)$*&%&)&("#%'$%*+&!"$#&#%((#"%'$#+"*#$)$+""!($$++&!*)(%#*%**(+#+(
@r6522
NGTNACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACG
+
!<290167>!/6)'>;>+!//AA#%(F%H8345?!06B-B"?+#;."81'"$G'!$B+%?%H?1:<<'$6%2H
@r6523
NAAANCGAAANTAANAGGAANCNATNTNACNNNTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCC
+
%&%%#'")**$%$##))*"&&(#&)!!!&*$%!+$$)%'!##"$+"&!!($$$'!##!"#")''!*+)"+**'&*(*"%%*(%&+*+!*'("%)('*)(#&$%)#"'!*$')*(!%!+&*'$'()""+&$"!&+%##'))$*()#+%!'$!$(&$)"'!+$##+
@r6524
GCGGCTATGACTACCAGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGNCNCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCC
+
,:BC3+2F?E2"A3-58HFE'=:8$>%(0.;&=(4+&9%9"/A<)9>.2=%*$=!++%A,=;62/E'4H"#G"#?H"G!H7BFCD32(2*;9%%-1<9%/=8'>:E;-$E.D*>$3@)G4*4;:#.0;*0@B,H>A.F(A3E2$#CG
@r6525
TTAGGCATTTATACTNCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGG
+
A6)09&6<3-@A625)(*-+F77#+-++@C;C".A7@)&'C#:$DH&G<940;D38E)?$3D12,6,1#&%(3
@r6526
GTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTNGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTNA
+
G!F&A0BC1<#.3(E#*#99+DA69.=/"8B/"@3/2((>==>0;G;B&)E6@(,$,<H&4G:=A:H+D:<51H#':D?4)"G'&<G(1%3H471807G#!>';
@r6527
NAAAACCNNNCNGNTTTNNAGNGGCAGNCNTNGGGNCGATNNGTNGNNTTACAGCCATCTTCCG
+
!*$%%"*#'#(!#%($("**)#$*&()$'"%"&)))$'%#$$#!#!$&(+)(!*#(#++'#""&
@r6528
TGGTAAGTCGCGGTCTCTNTNTCTGATGAAGGCGTTTACGGCTTGTTGGGCTT
+
&+!+(')*!(#*)*)$#"*$#*$&*#'!%#&(&#)(*%(()#($#)!*#+&&(
@r6529
CTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTGGGTCTGCTCA
+
@5?+##,B9.47?(+-H8>,8?EG)?/!4'&;4./1G)G,C?%C!D*G.%$F138
@r6530
GTCCTNNNNNGNNNCGNNNNCANGNTAAGNNTCGNNGNNANNGNANNCGCNNNGCNCCCCACACTAGGGCNCGGCGANNNNTGNAANNNNNNAGTNCACNCCGNTNTNNNNNA
+
$!"#$"#!#""!$#"##"!!$#!$!#!#$!""!#"!$!$!!#$!##!"!!"""!$#!#$"$!$!$$!$"##$#$#$$$"!""!"#!!$#$!##$!!$!$!!"$""$$$##$!$
@r6531
GCTNAATCATAACGTCCGGTTTCTTCCGTGTCANCACCGGGGCGTTGGCATAATG
+
BH9;)D-1(#)-!<*>(A$.28HB#E#2)(-/5G64&<+&6!1*1($99>2E/DB
@r6532
TAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGATGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGTAAAGCTCAATAAACCTGTCTGT
+
BF?<H'26"9<D+(D16951)'%CEF!'2D!&H*0!AG1/#7+130/.H4&&)GG/+71('*<'#)=<(A18!*!0?BA0)9F8D91-6','<8B-(/25C%EG)%G$F5A2;G?>,.FB.5/;3+@@2%!.714<8D(F>,9=G$'
@r6533
CCTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCA
+
!2#C,+%F6##39A=3)93.7"$@H'9'(/:'HF-/1CA@$A
@r6534
GGATGCGGTGTCCGGCGACAGCCTGACTGTCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTGTCAGGTCATGANCGGCATCGCCGTGCTGCC
+
61C$)+"!=<<D9!68G>!$22<9)/%+:<7#30>74!@8&#B5(H?B!AB,@C"F%@E:1543+&-6-(5/%>3(3(#"/)5FE3;/;;'*=,$E$?0,,C"#4D!%A78F$+GC*?@%$C3/DA
@r6535
ATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATGTTCCCCTCCCGGCGATAACCAGG
+
.4B2-HAA6-*"-4<9F>%:2>,(9-*?&+1@1*-DF<?-G,7?=*2725%=(DG1"?$5C28C4.F/80%FD-F3>%C5'/&6!/;742=47)2+8@%.-=*)6-2D#(7HA'*D69GFA!4(%#2*EE/0GE+.G
@r6536
ACCCCTACAGCCATCTTCCGGNTGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGNAGGTGTCGGCATATACCGGCCTGTCCGTGCAGNTTGTGCNGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCAT
+
F>6-.+8=,F<-,H$4$124!531F,3BAE1*6/B'F96D:956;'BEC@5FG5D2,$A"4<%&)2@A?DH@%1"7E0+?/7/*GE)&3G/;<(6>54E&753E($<3*B32;8+)#30A*C+15D9D<7"6&17B.EE,8@'@$/,*#B'E(%B7&259
@r6537
ACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTC
+
23;1@D)@.2E$,<6@0A<9/3:$?3!(GG@/;3,."8C06:;"G0(@<1H9!0-
@r6538
ACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATT
+
B4)*8%2H16912/6"-3D&>+)%2,9@34<*0/<4B0E:-E>A+4GB+8
@r6539
NGTACACATTTGGTGATCCAGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTTCCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCNCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTG
+
"&.4G2#9(7*G!)6+CA.&E-3+CA=A69%4C3()9+BB;>.AF2F+%=CE"AH<2,46:E$?<D6EF(9%,70F5)1G<6(.9#@D)D(2.!7C3"%44"00@2;!59@67)A/$2+4*H*1?7$6CB,ED)9AB(0;5.H,*G?&2$/57%3>"0'(/)B93D&1/34@'F&25>'(F!%#7.:H&-&/>D!E---(&9$>D*!-8F($0!3@H/F(0H.#&>"7=,A2,>"D2E..(!B*&4D;B
@r6540
CCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATT
+
43=DDDB2-4:;*1-65.F*E+;32.D2?/&+C;'B!88@9-:(?C/8ABG+8)$@7:<-"4:50G?8AB$)+<=:>@$93C+<-C#4':+!E$F;,<$B6<1?."7&+41
@r6541
TGGNGNGCGNGNATANCTGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGTTGAC
+
"($!%&%!!$#$&$*$&!)+(#(*&"('!%(&&$(!)(%&'$('!(($(($!#)(')$"*#)"*)!$
@r6542
ACCACGTGAGTAACCACAGCCTGCGAAGCNGTGGCTGAAACAGTTGTTGCTTGAGT
+
*(&#&))%)(()%("&+#*")"')'$(+%!#'$##!$$"$*!$$*&#*%%&+(%!$
@r6543
TAGTTTCATAAGAAAGCTCAGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGNATT
+
#%+!*')("$'''()))%+!"&'$&+&*&$(')'%'#%*$)*""$!"#%%()'(#&#'!+$
@r6544
AGTGCCTAGCAAACTCGGAAGATTTTTTCAGGGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAA
+
-,51D;!'B0H)9A!=8A09;6A:)2@(28/!9G>-8:56;@"'A+G@42$5>0>>6$#$0G>)=*;GB3<=70@H+">2
@r6545
TACAACGGCATTATCGCCCGTCTGCAACAGGNTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATAT
+
>=#:HE?F'*32.*-.AH>'#=>/H2'7+1F-A:(.E<G&:$,+-:3#8->2+$.'24.D3C<47-#5@7
@r6546
CGATCTGACAGATTTTTTAATCGNGAAAGGAATGTCATTAAG
+
A:()B4#"&!)!<2FD27'G(A5$):<E.&&%3#3729HD8+
@r6547
TNGGGGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGNACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTANCAGGCTGCGGCATTTTGTC
+
)#$)%+#(&)#)+%&*+("!#')$')!%!&$**!"!"$*!&((#"!)'*'+!"!($)!'$())$!+!*!!'("$$('"(*"(*$(*%#%$+#&#"&$)%#('+'+"!+"$!##$#'+$)&)*#%'&%"#$((%%&%&)$'!"#%#!!%%"('*'#$(!$$!"!
@r6548
NGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTTGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCAACGCACCGATAACATCNCATCATGCAGCTTCC
+
",(H.D1/,"1GH>7&7.47D.BA8@802HE>3"&%B=0!6@=E.6A:B2+"3>(0*#81H(A@=9>HD3)-51>+5&?B$)>%##D(!;DF4(4!8#DEE9.A3:7#;3"C@0971+5?+4.'(+"'?;@-E(*0'+==++0(;#&&,FA@H(!?B/%-F$,>@"
@r6549
CCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCT
+
>-4&+D5=/>).@<C;B$'C)&1>H"('D<B1.C3+#AEGGG&1$+H%!))28<?:%,=&"";42D8A9/<0:#!-3F!>B(>':-CF;6.)CCG1B+14/>BC1,;*%B6<%471,--E?%EH&1"6>:->?%17)4748F(0&-C4C6A'.D&850-8C?1)51:/0B*
@r6550
CGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCNGGTACAGCCAAAGGCATCCATCTTCGTNACATTACGACCGTAACGGGCAATGGCCTGCGTNTCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGT
+
+;E@:,E'?!>3/C477;.<.$;/=3AG22CG'$8.*/%#**;:'-!&-;7H701/D@3@>#+B">#@951C%<'FBH$,G0C,#<'-7C("@9@&/@0?E/4%A>2"49C@2?%5<F<9F(.0E#@,!$6;-C/:E+79A,'#4@>E?3-%*!7%-D)%DA0G+>C-.5$B)>')F
@r6551
ATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACGCCATTGGTTTTNCCA
+
8;'.>;-9F56;6!E@<D-,00,)6900,*4<;3!/!6-$,#@5@?+:F?A3H
@r6552
GCCTGCAGGANTTTCCCGTCTTTCAGTGCNTTGTTCAGTTCTTCCTGACNGGCGGTATATTTCTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGC
+
A>H&=>5$75>0$46#C-%7D.$2*2?2.!0@9B1!:G5!-,1!:F>(4E-G-)<=F#26,B!A0'B6-&;%;E)9=<AF0G+6-C2>0%,%-B&'>$/-&A5!%E,/%3AA8'E$<A8)4+A6@A$?"4.H??%,2C-7&#C0E@2);D.+4;/%?C7F;9"GD8:1=0*'AF,%<GHB4362(46?F*+8F<20>',9)G*+C3D
@r6553
GCCCGTTCCCGGACGAACCTCTGTAACACACTCAGAGCACGCTGATGCCCAGCGCCTGTTTCTTAATCA
+
'HE0=/@-"#;@>A<.=F!BBH&-A8G,A4C?%-%%>:;-0!F!A?3"%E<#53'?$*@/E3FFG6)/0
@r6554
TNCGATAACNTNCTNANCCTGGNCNCANTCCGCGATAAGTGGACCC
+
*##&#$)#%")"'&&*!)#%))$&#!(%&%+(+('$&&%!&"#!&*
@r6555
GAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCATTTATACATT
+
H=43CD5@.!B0##+1?1'71F38%;F64+2/.7E%#2A5#8?;8;"$%BH@=//F-F17<>;:.">0;!#",1!0'=0;2+5H48+4EB%?!2$334@B::F7$G?#$3HE((3E<''7).<'(/!6(.71'=@-0D)9DF.!H(7:((D():.G0C$<8D1=(H'*9;!H%A4D(6:*F<%4.&#??'13:.,$B7&91"H(!<1-4E91#041&')A'':"AG5G84FB6*/@&9)0'!;/#&3:C)$?!,#0/6$5/-3<G((%B)ED"$+;HA'79AG/.86?CHC=)(&#A32=?)!A(=.6
@r6556
ACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCC
+
4GBHBF''"6/G;D$@A2/3G9(5)!/7':1?-B,'37"C")/@(2A5E3,C1G!A.D9#F&=3%C(%*CA)H278#H*27
@r6557
GGGCATCGTATTGTNGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGG
+
H:AF78A>)1)#=C<-8G;D(00C)&'';H&D7:!9!1)!)$2//3;HHF787,-+G(B:<2F%)7205.&#:2/4
@r6558
NCGGNCATGNNAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGGCTGAACTGGTCACGGT
+
%('($*&)'#""'&)+!!**#"'##$##+"'"+&"!)%('#!''())"!%''!&%#+!'$)!'!&!+#*(+#%
@r6559
GATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTAT
+
E$B8/='/.'9#)=40,"GH-26>$B1A96EE#1F</3,'H,.'-59*&98
@r6560
NGATTGCTGCTTAGTCCGGCGANGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCAC
+
'@C>)*3!2A6681)C<B61B..--=</*$1)C4*7554)?4)02/-F7?C&!;(!8#C.5C!
@r6561
TATTCTCTCGCGGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCC
+
6F:<8;0'8@=H=*=-C/;,"FF86*/<+#-!3').BF190(./=18H!F!3&*
@r6562
GAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCC
+
.=+<H;2=E<G:%7=7=8;2$<3>0=9>B"78F1,+*%<<=)8*3!2EC$BC
@r6563
AAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTT
+
96$-:".H';/>9$-#.(<?'-G#E>FC7(($"@G.,7C7F$A<9B&4!5F$D+-
@r6564
CCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTC
+
=DA+#D=55@3)05DGE/6:A:),)&HF%A-(:H4?@F5EF=C5*%:&43!"8)&AB,B*<$
@r6565
GCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACNTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCC
+
.%D>20'E!-0($*0-+93(E0)AED1G7'%:G);0E=D#9*":>79=6B9)C251H2-.)GG,)<BC(E);6;#@)#"7,<@G8-*,6+;A'0?8F2'!75C:)+5*C1A7&DH2#>*-(<1>:C0=$BA18<7?H<D#BH@"@:1),(C/*=57)";"FDHG!CH$&3?:4,&(.).DB#4"C&CF;.7<)%/3.D<H*FA!(8##*;CHH8'&C>)()!0(.1"
@r6566
TNCATCCAGCCAGCGACNATGCCATTCAACCTGACGAGAG
+
@*$41&!1AGD#C">!&-D/C?*&&@0:8GE->D-??"&)
@r6567
TGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAA
+
&G+A@8)3H6438F$+B/76+D1F+H:#!6<'4=(/?H0%G+":<DC96)!*G-@%0D27?.)A%/5F6GE<F/>':H9F-51.D83H*&:.7EG75A-&1'<;;13BA&%G:@"(<1'91,/!;'<=F=3B)7
@r6568
CCCCATCCNCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTT
+
4HD,@DA&.2CCE@/#6H8>;H5"4(("4:7-(2G=<C@()E9H9C,":CG'4H;.3B,E>G(F?F%3!0*F):29.+-2E5EHF-21$<""H:G?H@?+B6$(A*'-470B*3<'
@r6569
CGACAGCTCCCACATCGATCCCGGTACGCTGCAGGNTAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGG
+
+0:A+>>&7(*1HG+3:@04C52;-&.FD0H#;=H9)@4B!''%+E#<*%5)/2(&G.78G05<C27;H;/0,B
@r6570
TCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAAT
+
>50+,63%#'755F:A0A>C0#5&C@!3AEC)/!6&"@('5G3G934%%?B7HB'4$99+C.&-3<2#7>C8)3@+=%?1)&3>;6*0-.&,?=0DD''-=(*##B+4%;.%;3-'
@r6571
GCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAA
+
%>("8H'/B=9!#?.+FB1#C:2+D&=)73A8?089"#=>0#;4=H+
@r6572
TNACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGCGGCTCTATCTGAACGCGCTC
+
$%*+)#!"'$*(%"#')*")"&(%&'!#$!"#!!#&*'%#'!'+*)($)*&'&%)#""#+())%#*$$*("!!'&(*+&&&+*%)
@r6573
ACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGNATATTAGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGNAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTT
+
1+(44;4A1F7:0E9?5%!4#)2<?8"7#.3F=*9$1.*:87--;$#E*&//:3-1?"=A-6';614C,6"';0F2D>;B@9<(+09&+(G/&;2$-35B=FD?G+#7&(;C'6$6'.'/:07:77CE4A)#9!BC/%6D-2:'*@!)H
@r6574
CTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAANACGATGTAAAAACGATGAATGCCGGGAATGGT
+
3=6!0D@,>D,"A?"B9$H)$;18<:BCE"8/=!(D#.B>F1E7F>D0E&!&A?3:BH2G3D45.&4@#)@C47+A"6?/F?">)'&,H!-55/=5473+4#E61<!%
@r6575
TCCCCGGTCGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGG
+
:8*4&(@#;2F"A(8?A/.&%!:@8"!-+=6/38DD5H3G+C)5=B7B3E:1
@r6576
TTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGAATCTCGTTGAAGACCATCGGGGTAAAAC
+
H"E#F.!8!$D526C7<2C;G)C&3>'7;B96>;&4%/"=%?=H@+7="#$$/;28>,8H@@1)
@r6577
AAAAANGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTC
+
51?06@)9''!.$09)/<H%?<"53FF(2C#/E(#H;A/!'445(+75!9E!G-?/&*72;
@r6578
GCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCTCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTAAAGCCGGCCNGGCATAGCGTCCTCACATTTCATAGGTATTG
+
*CA(E=,>/6A=0=8E6"4,D-<!"E%;>C%4;;FE39==55CEF<E/EF4A,=&')B#F;7-1H97E-!)9.9@--"!G+AB$D6.,/EA'+B/6?,:B#F29:B$;/#((H!#%A<%G=8G,3G:$+,/)#8D3)3!?;<G><9%@8/0H&7+E5H;?8=95CB8)B;,G$/%*A972*53/26E:(8!.C&.?,%<(H)%>>.;%*1.!%*+HF2$1G/?%9;3#$AAF
@r6579
GCTTTCCTAACCAGATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGGCTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGAC
+
$)/(++0H3&#5;3G84A<#6&&>%C4C74*9+HE%42))9D-AEH+C3.+(:?,*!D/F/HC'1@H,1!F#&'AF>$,:"C-E-3<DC/=&GA"B3A78$3D,H$EC=A<!??E!@>-#?&A.'*4B&%?6<#89/0*>@H$A(%8$4:5;.5FH&0=@G%=A3.2G2("432<-:E0F"G%'1/+/&(%=20(@4G)+@D6+*6*4",7;-)"(9'5A1(8;-?&):!F#=$',$.#*3D@:B&+$%60A:@8:B?%;"B
@r6580
TATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTT
+
-G8*/=GG<*#G7!9,""F>"7%#-9$%F&AC(#'0#%E6<8:.,&AEB,07?*&G5E&"D12<"6@);#B-
@r6581
GNNNNAGCAGTACGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGNTTACGAACGGCTGCAGACGCCGCTGGAA
+
(##!#&'#(*!)+!#)'((#'(!!%)%#%!+)"'&*&%(!"&$$)#+%!"!$)*!$$('"&$)&#&*+*"*)*)*!)*'&#(*)#%"&
@r6582
GAAATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGT
+
4/%E3/)F50F<3HB"0FGC>=%"@&3,,?$(>49D+!9G=&C+8.24CE@,@)G0>&C"?)%$3:/$*?
@r6583
GGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTNTTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCNTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCT
+
.2(497(12&/5!6GCG(D<)-698A13(*>)?#%&F#9=4'>;/776-F66-D9*&G%A+'9+),9=F>8<<HFD8.02D+&"01=A*2,F=#.'@#B-/@=8D#@20A.-.),9.=1$062?@#?&>H8"=A!!2B-1H5!9$7*<+.B$;92?&8+HC1@5>6!0E"3(9202,!!#4*:(E.22#CF#*A-H6H@)#/H
@r6584
GCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGT
+
,H2%*%0"9=,"=$"=*,(;,#!2A<<#;%;"F&(/D*-#5C1D#)5)1B'@*H3BF$!//&1:.'=G+
@r6585
GAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGCATCGGCAGCGCCATTGGCNGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCNATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATNAGCCAGCGGGGATTGTTCACCNTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTA
+
24%7-/6+)@6B,&)%'78<0&9E)*?@/<2=(!6:-G#H%8A<@+G1;<GG>7#0202!;'63=67**1+8'D$&C77$39%E%"(>?G"<$-72'2-@"DB'#?(2;9;9"+-$E!3C,.1<+0B)&<CE7-6(,E2%3$C-?.&/;A0?C'(6<DH-!G+B6!64;AG'%01'/F#$)0-($'*%3?D2GG"0-#$H,$>1>1,4+>$/7/B>D1!?7E"$66C>8%.%2"E7)>32:*1$#?)@-G0-#$;G=&>G;H*,B/A&==1;742,:;@/E!4'C1$B4
@r6586
GAAGTGCAGACCGGCATGACACAGNGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCANTCNCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCG
+
2/F(@%,4$646AC?;(<CF0@>D2==%FC.<D?&!%G6A"15;G$'/8?A>=9:,+9$':62HF(,)D44C'0=C/40=#+&.)@?D,!((<"*080F@6!*","5?B8&,>2"-H59'=#)%'95(#$+%EE&?8F5A&
@r6587
CAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCNTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCNGCCAGCGCANAAACGAAGCAGTCGAGTGCCTCATTGCATCGCTTTTTGCTGTCCCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTNCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGT
+
71<&%,16G44*(+@09+$1&6=FG4$?*"A2+1'$>D334?%;!#E(:CF9H*$.#)8<"97*>2"A>F)<4G=@D942A(1;5!'!%.F&!%1D1+F><@8;.GC*#+0>+?!C>F?@-:D-04>8B=';0-"E?795G?&;:4).-BGC8>!+$((/HF.,2F*<1:5.=00=B1&1,E)&.C8@%08-6+D!;F1-;#;>GG&:H1":6/E&*%H5>7642-G8-</3=C/B*5G-D'7>7H&;E;5C+A.@:3$2E.(9G-460G;*DG(7A7$'!69)-5:2">-1"46,A@6B>.#@+"GD<->@")@EG@/55##5;&8(;G7
@r6588
GTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCTGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAATGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCNGGAAAAAAGACCCGACGATATGANCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATNGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTNGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGAGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAACCTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGNTTACCCTGTCATCAGGTCATGCAGTGCCGCACGGGNAGCGGCAAG
+
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
@r6589
ATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGC
+
;F?&.=$"CF%"G"93%;>/!%':E4@$C@70=&,*#C$=6H'2#.@$+94%>D)>/-.+*%>G
@r6590
ATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTACCGTGGGTTTAGTGGTTGTAAAAA
+
*>!,=:&D7F6A<$3:,!A/#"F117;&-.541$&+7?"C;5@!8DCEC)"",!<>,@G<2"B3H5.*,1%A@C#9(7-:79"2..#90/1/><>(%BE=E+-9&?AHH=-#@7-A%0$#!5$AFF(;@5>5HF;"G7A>1&047HG336=G39*0<:C&*46-+#,+=/0H-1B&#*&F
@r6591
AAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGG
+
/(BB%HA6H!9;!%@HCE#$9D=@%88=(!:*:'D58!/3@!@%AF"9C$98"1C0:3+?'$F$=*0/#>5!H52&$"421*7>-H()=C5FH;6$E2))#)'4&H"G8@8G02=E3"6!A288"-+710C,!),#E0@A?'-;/;A="&/2F)+B=6!FHB(GE=;*F5<4#'/
@r6592
CGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTT
+
@"<0>;+D49&0H.;,<F)A$&--)/,>0@3&%1H1E5+,>D,)>8"9,:5=!'>35!2%FE08(6.
@r6593
GCGTGGAAAGANTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGAT
+
,A")-0!CG&B,)+)41@+4<@2#/8C0+G:,9(4!1>1(HC3GE>=.=;;FF+H*<@(#@C(<7>+C&'/05:).F@0/(H>3.F=:+7
@r6594
GGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCAT
+
G5"'*89'.-4#CD1,&$;7F9+.259;C1)D1=/"<03+/<*9957<-,2/@>-F&)9
@r6595
ACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGTGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCAACA
+
(=><$52?7!209;F<H>,25D=#<=!1F%/7,8B.5F4.(<!A0%8$1GB9BH%57/?GF!D:?>$&CE)=%8:0(A6#/#";8152@)19!9
@r6596
ATATTGCAGAGCTGGAAGTGCNGACCGGCATGACACAGCGACGCAGGTGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGNTTTGGAGGGCAGTTGCGGTCGTGGAACCC
+
&=)%:G1D*')"G/-4%E*)B$9-82DB:6,4>#H.D!9-0"/?2FG27ED'6-!!G2"82%*C0>D56.+$#0./6F/64'HE(&?D7/2"%(.<#H:!$8%6+G?@B%8.22/%=4EG(88.:;?E9@D&)*<B9')#C<))9($(<''0#,;E?)1;34)>9>@A0?7+&67!(2D;(%"+'3
@r6597
GCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGCACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTA
+
$/0-$D?AH8-"%"-2"BH"?C&:9&G,3(>1;/#9?23A;6=?%.>.>F;14"@D!=D6,!H4-@31C-H!B"B2;&=H9?$6;9FF"DD.//;34=A76:>H:1.:/<$FEA$5%ADA3$?0F23+2C!)0#%88CB!</"&CG)=:7!56?$#$/*9=",
@r6598
TTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAAT
+
)85!C2CE27':()CG&!*%*5!7D6F9/"G(6#"C60%,C%(-2.@!?.G<:6GG=8/"=D:HC;;7D6EG!0BD4)(2>B&A?3;?@?*"%??9
@r6599
GTCTAAGCTGCGGTTGCGTTACTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAANGGTTAGT
+
GC4)*.C+7'9G;6<>CEEF+)0(%C&(5=,*;)D385+4F)-%439)0%3',$A0">0(A1DG.<>G()F=(1391)G0'67'&#>,'E!#36E9?#=%4'A>A5$32>C5:+0#1?@>E=+$
@r6600
NCGAATGAACAAGGCGATAATGGCGCACATCGTTGCGTCGAT
+
#&(%H':=8HB?4:/$:0C#:/7$#8;:1?3G?BEGG($'?4
@r6601
AGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTTCGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTNTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGNTGGCATTCGCATCAAAGGAGAGTNAGATC
+
"<@:-F+*=H5/A93*1.E*=3C9&BE;>H-"#4($;?)*$B/.0,>@@=,5),$75'3<;-C7"=C8G<06'&B(=4.)-(/A,EH$2"<!G?,.,1>*$#'!#C%'9&181=$/)B")3",7'0-/)2?8E3*C9A&EG1>5D(;$!GF@7311HB#D)?6H-:B9"4&(2G-A,/61AD@-BH94;1G2G<9"7@'EB/HD8D5("<'B.GG<BC:@EE$5-!#11D;.<9B.!3H&/:.?D3@:$&F*-??22H8A>5,5852)?H#BBB/G3;=G%;&(%*=FD1C$<;@A$4G.E+;/G@9*-$35:@&12=-:>31</#B28,+-/#HD$
@r6602
ATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGAAGTACTGCAAGAGGTTCCAAAAT
+
58))9.G)G@C.79-H"0C?+D;,7C>71H/BC*>E85H'E%$<@/#A2,":$(/+)E77!H4<@!=8<(D#F%*#,5<F75)
@r6603
TTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATNAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATA
+
-A5$AH@FC(B$1!*1.F(69!.A;4;8H!(99#:0!>-$3%;E8=(;.H-9F3/;:@EFC@93?.1=.G7?;3D3GG+0.*F>#"7G-&$(3H(-7&F-=?%$"-=<*7)/!A-#?!#@?C;+2"G')1CH'7,&$:;B@D=2;1AG$9<D$<B(/1%+E?+))7$!&0:!",A)18=C31&5GE?@@=%G@CA(2-+G7,+0,2E8::=*)D+*-0$")C4+G&46,-(B,D$=DG0%!!E89
@r6604
GATTGCGTCCATCAGCCAGAGTGTGGNGCGTTTCTCCTCTGCNTCCGGCGTGGAGGTGGACAAGGTNGCTGAAGCCTTCGGGAAGCTGACCACAGACGCGAC
+
H>3D&(.A.<1>!(92(H?1$F.D=:@+1+@!!$-DA?'D01/B3=,>E/:#!)27<>:9?B2//!DF181;F(51CG16B5(2F+B4"8%-B<CF-EC8,8
@r6605
ACAATTGANTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATATNCAGCTTTACANTATANTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCTTAGCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAG
+
(212=.H553.*F7;;>)6.D/2E?5F48)3H8&&<+'9'#!0/1?,.F>CEE&.&791/1G"18@-"D33#@?!E*C#!8.D&7&!>0HH,:A2&78'5?9)G2--AFD01*4DF,<)G/.@?&BB-%3#=(,B6,D'?6)-EFE1;:?.F;?;#/3BB:6*0;>'(ED6!''*9"*:'
@r6606
CATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACT
+
E=D":9?8:#26.2=8@;)@G*"2A#2%>A5F+4(<B+C-F&7348=6>+D89!.
@r6607
CNCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTT
+
B5CD=60&F#+>@GF#3C=&!@&%&E.<>(G46CG2H1=CG5+)-/5!!)6C3/2$27<)>:5+
@r6608
CTTTNGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATTAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGA
+
*%&"!(($))+!((*"$"$#*+"*&#('"+(((%')'$+&$*%#!+'(%!!%%'"$(+&"%*!%**'#%!'(!("%%&!((#*$#+%('("#+!*()''+$(!##&#*''&&
@r6609
GGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGATTATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGANGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCAT
+
E9)E!G<*;)"74(/5GDG<=GE/'?&G5.+6=E>??G,G69F,B=%?FG$E62CB$&8+?#D9'DD<D1!F+2/.G.9"!.7)B7#G*E.@5:F:8:)A;AF+:(?G,;!=!>"@7C*.7*E&A"$E6DG,9D#7*C>D."FB0DC5)&84D.#156
@r6610
ACATGGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTNATGCGACTTACCGCAGCAAAAATAAAGGGAAAG
+
)3H#1D0=?1#HE(%%)5B1C8.F.G&$$5&H#9=9;/3+$$:$#>4!'>73)62!?%H>'B6"-A@';!/,9.=&,B1C5!-6BFA(10H?<?36@/<,&BHH;(>+*
@r6611
CTGTATGCGCATGTGCNCCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTG
+
"=/">-/$C.*D>523@D=GE%7"09D:#C.>()G$6/0%</%6F3$H+C(3/<,
@r6612
CCGGACCCNTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTG
+
H3AA-A!@9F3F4;3-"939&A1B23121F(,*B,1)B<,*?CC>)-6A;A#.-D1H<?7<.?26"="!,4/)%((5.=A-AE<%;.18;?,5;02/,')
@r6613
TAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATNACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCA
+
B5<=:";E@+F,*6B9(GD38B/%83E-643)D$'5G+,@C+($8>+>*)H2:/+H@5!(6@>/5F#F;5H2>?H&<)3B>.#8<;84,0<2>0C1<<927;*5,9%8;.8
@r6614
AAGGCGTTTCCGTTCNTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAG
+
5<?%F%-.$*3*=;HD&.D?B>!$F-'343>8-&;&(.-09#;CE:C:+A>GC<8)>-,6.@<B.9,0#/G(1(1"$!'CE;?310);/4
@r6615
CATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTG
+
(-2<(<4@.*.C8$>8D"7%D#E'/.1.0DF7A)*=04=<F!'51=G'1$C.9/:.*=%*;,+<:B9,)9(1-,+4!EF28$)A.6HC62G=%D(=>;@/'=$2(4(GH:>,"75GB-CAHE
@r6616
ATCCAGCGCAGTGTCACTGCGGGCCTGTGCACTCTGTGGTGCTGCNGCCAGAATGCGGC
+
B4%D)-*=0BD;.(&A8B:6:GEG0H.5:C44//%)A#5E($;9G%A$=$9>//D<'7=
@r6617
ATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCAC
+
<"5HD&74/@.:E?25;1(%+(DA@@$G)A#%H9=*EE3737*
@r6618
GTACCAGNCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGANACCACCGNGCCGGAACTTCATGNAATCCCGGGAGGTAAAC
+
+5.*?FF:-!->B&18<?3,67E8:<7>G?/8$G:.)@(#:846)A'A5)6&F)?C)4B@@=G:F("(5/H7"E2"(A>.H$B-"742*(.$19#&G-0'24?/EC>8E71695>
@r6619
ANAACNGCNGGGNAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCAC
+
#")%&"'("()*%+!!')"(&*)!'%#+%))!*'$+$%("')!"$#+(*$%*"("!&+**'+"!+*&+"")$"(""')$!###%##)%*&*%(*$#)&$%*&(+*%#&)$'#!&+('$'+#)"+&)**#'%'&*)'$'")#+)+#*++"+(""$#!'(!!!
@r6620
ATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGT
+
+9!..>-@)"&9G3A=40$=("..7G/FF$#1+D="7@B5
@r6621
GCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTA
+
+47G?$=D+C/6?F@.-F).G:=+*G5("1;1=::;?E5D'&)53%DG##6/!6$?:0)-2$27)0*?H
@r6622
TACNAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTNGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCT
+
<1/")'H&0457H%1.:FF8/#-D!ABC)E;&&H+.H<6&H'A0,?(/(##/8=(%"+:4.&.**2,+.6*/9G$D!?&1?6E<.@&8</..>665$3?B$+F(
@r6623
CGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCNAACTCGTATTCGTCAAAGGGATAATCGGCGT
+
27?5<620)(A/19,/,'1F.(;",9DC<C0$@%2'*&=-74DG<$;F8*(0:0C9@G?>'')0#<!F&F@:6G8H))H+51H%9A,;?&(C943/,<+G?EH.'%4/6=8$FB.(:55(/%
@r6624
TTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGCGCGATCGTGAGGCAAACAAAACCCGG
+
*:'/9=+9(826:!G#:18+7AC8839,<&34B89,54;@.%">;,+G#H:5C$'E$88!3:5"!D/=D6>+:G-(9!7,9,)16F%=1&H3:-"$F>2@.H;55=46B59@G$9=-4F%0>/90?+C<1
@r6625
GTGGTGNGNNNNAGGNTGNTGGAAANANTANGNCAAAGGTACTGCAAG
+
))"#%"!*$"!!(%""$)%'*!&&$%("))!!!&*(++*&&%+(#!+&
@r6626
ACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTA
+
>!653:,F$8#*4&E643;);=*=F8D57@$0F><>&/F%>>0#G"F@2
@r6627
TACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGC
+
A48@50><$2;7)#";7.8&@%$>%DAA:2"=0%?6;E;B.E55%A
@r6628
GNNCGNGCGNNCANTNATGCTCTTTCCGCTCTGCCATCACTTCANNATCC
+
&!(%%%)#("$""'(#%+&')%!#("++!))#&"+&((((#'!%(##"!%
@r6629
TTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCNATTTCAGCATCCCTTTCGGCATACCATTTTATGNCGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTC
+
82;%"B!"8<.HD+*D(&F48!G22:"=(./2D36A'?'0,92HD454:--!<F.5&-:B@14+79!:62+-&&?F2@<2>B10)=AG$8:%.7'-.E,0F3F4+A%.6=A++::%H)+$B;AH="F++$"DB2$-H"3"&DG<,5%,;-C3."13-E:","<@++>@908495'4>&B68F6')$>.;F(?A1C')3-9-(<B'G+#>+-FC:+-!+&)7,6>!8(8+?DCGAB7/=A/*@F>>/5:#HBB+1AC!H,AH
@r6630
CGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGAT
+
A6.5?@!:C+$>"1:,'&?,>D(D$9DB=>B2$;!9:;D+!H?DA:1*7#/#5>%C-6.2#+'B&,.!)"#;>H(!A:
@r6631
TGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACNTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCNACGAACTGTTTCAAGGCTTCTTGG
+
0GE1?&B.*@,D:B3.'9,2G@&"5EF)<0:F$)52F.E'-5+!5?<1B4)H-03!(=)=.&H*7H*'F!!0+D5#4*28(AC30=@G>8;>9H@@(-!(?!%'82+1/<?/;$<5>/(H5$HDC6(,".DA5#D(7>C>#?0"@77&D7GA=@-../:4+!A)!76$-G-<D'(<+.$-/.6A!9:C:G&"E;))H3:)'.%2F;3:/6+*FE<9(;"#CC?8FG#.>("*6
@r6632
AGAACTGACACAGGCCGGAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAA
+
2(#4*A/)!*5>-+3,&&-9D)0H+62F-!5D4?/5=)./.<@14E@;"<-$
@r6633
TGAAAAACAGGCNGAGCACGGTGTACGTCAGCCCGGAAANGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTNTAAAAGCGGTGCCAGNCGGCATACTCCGTGG
+
B%;027@5C&!A9#?79:C?;924F6,*E*%/;"1B>1>':3'F!5+2!D//.GD@AG5'0'C8%'3@>7()0H!C6BD/@>)G2.&DG;,>##&.:D4:2(8B>;C=3H)
@r6634
CTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCGGCCG
+
E"-#@/E4,<#5);-("B&F+,7-73?<F$!3%/!,F-77$'9
@r6635
NAGCNNNTNNAGCNNNTAGAGNNANNNNGNTTNNGANNNCANTGCCGNTNCGGNNNGNTGCTCGCTTCCNCCGGNCNCTNNANAGNNNANAANNAANAGAGANATCANNNCGTNNANGNNNTGNTGNNNGNNNNANCNNNNTANNNNNNNGTATNCNNNNGANANCNCNNCGNCNCCTGCGGCNNGNNNCTNNAANNCANGCNNNGNGNCACNNTNNNNCGNGNNTCANNANTACN
+
!#"!#"!#!!$"$!#$!$$#$"#"$$!!"!$####$#"#$#"!#$#""!!!#!"!!"!!"##$#"$$$""$##!"$!"##"""!"!"##!$!##$$"#"!####!$#""#"""$"#!"!!!""#$#!#$!#!!!"!""!##"$!!""$!#!$#$$""!#$"#"""!"#"!$$"$"#$#$#$!""!$""#$$!!$"!##!!#$$"$"!##$$$""###"#$$!$$"#$""$!"!"$!
@r6636
GTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGANCGTGCCGTTCGGGAAG
+
4,EFB?DD%#G,428HH"4=4F5"';3>$+,18?4427B-+(G0&,,H&G/501"95=!>33(
@r6637
GTCGGTATTCAGAGTCTGACCAGAAATTACTAATCTGGTGAAGTTTTTCCTNTGTCATTACGTNATGGTCGATTTCAATTTCTATTGATNCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCT
+
A<%.1@A-2<2'@8AHE-:?7<?=F>5.(*!'G2G(%)!4!,%>@BD1$)&+:G-@AC)1.>,A</0)(4;$"&!E+:7%A%0+"1))+!!6$E1#6#D.28@:D!80#<1>)>:B8-0D)23#,D1"!;0+G<*.$AA"H3>90)/.)4)$F%9G>6>G)9=.:7:'C,;44#43E6:D6/D=3H43B2/7:4'H=&';/D>2"GD-(D")BA9(;H(B9&(#C/BB7D2@?#G3-.=
@r6638
TGGTCACGCAGTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTC
+
CD>!E2:'=7?,1#-G"AG1'F4!A-H-AE>;+(H!E4(E83?19&+A"B!7DF$'#;/HBFG#-.=64):*23F@&F,C8AA=1+/F+.
@r6639
AGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTNTCC
+
GD":-!!2*/F/3916.>GA/,$<1.1%>E8A%2(2H96340#7.G-4B$"3%63?8@,;3;,2,4+/.#,3<7H1&.==')-G;)=>E77&9"=.H6#
@r6640
AGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGC
+
)+#"*(!%)"$"%'$+%''+*$($"%*''+"((""&(#+$"%)!'##($')$!+#()"#(#$'#*$''%!%&!&"+%*)"&"'*$*(%$$+
@r6641
TTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGT
+
/$5F9.CEF(!&*4'0$:G'E<%A@+*(?7E;E!"1H18#@37-E!G"&'H@0#BBF!)+0'/B5#@8<8@">,#5
@r6642
CTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCANCAAAATCAGAGGTAA
+
+@?*4F>?2???@<A<1'GA!96>?5*;@7(4'->+.)0?5E863:-.B'2>&*47E*96=+0,=<*!$.?9B;5(-B%!!&9+2&9$,:+.)G%'3@EG)B$.0D(0%G;46
@r6643
AACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCNCAGTATCAAGGTATTTTATGCGCGCACG
+
.9293@:%#:C+*'0F'<.C$+7=-?7C!.98#5&>%E:G-88?#,1+=58H9>%G%D7<6">&,9H:1*%.
@r6644
CATAAGGGTNNTTGNTNTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCANGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAAC
+
!)""(%'#!$%*(*#$$(&+)$*(%!'#*#)*!%)**'"+(*(%("%#)+**''!)+'(!)$'+'%'&")'(&&$$$&)'#%("%(!!!"#$))"$)$%!%'(!$')#""+%#+"'#"#(#'*(%"!$+#*&$#(&(%#!)%'#+$%&$*$(!(&%#*#((#(+!'"('*#+*$%")(**$(%#*!#
@r6645
TGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCACAAGTACCGCACCTGATGCCGGGTGACTCACT
+
B7B*19H71%;7G(C(B'A:"(;3;)%F2@!:/D'H#$$%,)B!D2+*+918$C2,#F5'?+:C06F+GA6@*.)(4/.">*-%")18,F9F72>,/
@r6646
NAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGNCTGAGTGCGGTTTTACNGCAGAC
+
%;9*!==BD#H:+/0&476B;&(89>;,CH#9-0.!?/9H(367-.6=399B$?+-4%C')(E#-",$4#'0"+*C:$>,B2%45.##:=4))*-6)(1)F*=A@,"*,$5.3A7.33.-;A">D>><64.2E$$A/?H"868/*@(5A%#7E1,%0)*A('E'<.H2%!+(F?)(*.677:<$'+07+'<))+#5BE#7:<&&1<'!#,:H+=%;7('F>*G):E*9@G)6#8"4F',F6(C",+5A.D@@?3;)'7F1;#;>G"><.!>,2=-$!0=H-==.(;&8&G#2)B'%HA-+@&;6@D&
@r6647
GATGATGCGGGACCNGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGAAACGATCAGTAATG
+
=4D;%!22//HH'B"-*)*5"(F4%&2;?>./%9.*!.<G?DEF'&,C!:3F#3/2/A@@1<C?,A)(=6#:HH?:9@8=G&HGD!-=G=!>FC$'/4$*!5@$>).2!7D/4=.::#;=%>
@r6648
TGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATT
+
@'%*F12"%0(18=$G),."F.G"*@%02)1,8:3=!#-&.=+=6=,!:3.D<*)B4<D>)EE,(
@r6649
TGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTG
+
9.;#=,:)%$-?+4@$49::A$.>1+F!DC)6/$A)!/1&8H!465E2&/6C.)&BB(--*68;4?!7-C$3>$-3:(@3&-.#"FG0&@58@+-39>@E
@r6650
ACCATGCAACCTGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCNATACTACTAAGTTTTAGATGGAAAACGTATGTAATAG
+
E*;+B7((.*HE=3+CE<+'8C!%:;*7+<0,2CB9:<+?A5&,G6,0/>60G-->D<907'20B*+,H#!!)?7)9*%H($F6,>"4!3-5<'.7-+=38;A;/(!>$%+A('-,$C@-386#9
@r6651
TTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTNATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGNTCTANCGGATTTAGTGCGGTTTCTACTCGTGATTTCGGTTTGCGAT
+
C"#BA$-.%&.>!0G"+"".196C01+C37=,2-H1E2-+8./G>B)'=BG"=,C!7)H81,B2F>>H&#"FG=BG'4.D2G>+4(>!0G.5A*&1=0;=.+1D-29B7,!'DEG='6%=0)C:5,"/6/6E!#(B>C-B9G.*7!8570&09
@r6652
GCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATT
+
A:G#3;D1&!EE8)=/)-!:/!#!7(4+D1(,)3(=F25=2D@DB="E/"A!,35%7674
@r6653
AAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAA
+
A#!>1A00*>8,=(&G(7#)#F.,<0F(0+(6&6'3$CH:-<C:?6%A6,')%$&HAC-ABF!DB#)#=*>(2
@r6654
CACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTCCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAG
+
G;:4@/7:GHGG974$;"'DB:0@(B&%-.)?'#;@%"(2C6BE8+1!.7*;0>!-AE4)B4D$C'<>/057794<7!71-$9+8D.@D8*$=3,*094)%$%>&$!7@%F>7,C":8*#7/F)0#%H:)G)25<558G2;FC6&C&A#+*"4@$GA-F!,626:BE.D0?$;+49
@r6655
GTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTNTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGNTACCGTGCT
+
82CF")6;)C0.86!5@0FGA,;:8:9A0:2/@E=>7E/2.F05:=+<0'-?&'G4F::E:)A..6)'@F*940G-$8.9CG@#26/D("#1(7)>/H>19G8$4=1>'E4(/F3<GA=%-F=#-F)#*>C7:')BF7*>FC>%%"6,<#D@&(1$;/.1$>;E;#=&C+!9$,?8>)7'F;9B-4
@r6656
CACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGA
+
F)H<$>7*"1='/=#%=;'E"1'&E6G/!*-+3&G8E<HD0&2;5:#9D4((2'.906;4ED#14070A2@=&)
@r6657
NATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACNAGT
+
%+#!)%("'""&)%((("&+"%$%)&(*"$'#&*')(!%&'$*$+"*&
@r6658
NNNANTACNTNAANTNGNTATTACGNCNNCTNACTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGANGTATAAGCGGTTAGTATGC
+
#"!$"$$'#&$(($&#)#%$#(()&##))"%&*+)#!%%)$"#%##"(#+$#)&"()#+#*+%(%)*$"%*###&'*&$$""((++&')*%+&(!&+*'!$+!)#$*'*'##!*&#*!'&'"*"
@r6659
NGACTTNAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCNTCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATA
+
#3&/2*#'"G9G@@.1886A5G<(@$/$A%;+@"!/?#3'E.9E@E)$D8&%#!1<0H&'DD);4'!H*(>8?C'.;5#7C<H1(1%(3=G)0"9%-06G+?H;<..BB:,E,1$>6)!"E,B/#??4<05>&6/919G9FB=C/!B&
@r6660
AGATGCGCGCCATGCCCGGTGACGCCAGAGGGCGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGTATATGGTGCAGCAGCTCGCTGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCG
+
F"@A0&22H/B?A#*</.6>C="$!B:,<C!<>.0-."1*B$#%2H!:%:"<CB;>0:-G(<&.2AE?:D+2?$92''D)-D66B#"<;0)#50G@-(D+23,&08*28/?/!::)-D475!EB3/2-&-B$<5D$"HF46B4@G))7D5>B#=;)62"<4'<%B$3AC*:G-"7''39+;GHAD!5E$;/0+7.%69+.,
@r6661
ACCGCAAGTGCGGCAAAGACGGAAACGGCAATACACACCTTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGCC
+
F@749'6F.@B;<2E(5%/F3FF6)2-D2.(85)#'D4.>'-F0:C/'((A1+A(01151.9@+:%(>@32%5<;&?))6B#<%;"'"08:#,#&/-/,$3,DE1>%975;0F7
@r6662
GNGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTNCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATATTACAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGNCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGG
+
"!19&@G/<-$)8);;039",B%GA*(>2**D=/@5H7(>,"8@8.1$F$>B4:F)2A@,)')=09>(&0"?("$D:6=<CF@%%@CH"@0H<*)$?3G=68.-5-4;F.7<<92+>:'C?<3B2(:-2AC6&97(==++B/7"59>7#)E-=6#-B!!4:ACC-0+8(19H5H5)D1;A,B0B4800C'(2'E+1D)F#)>!#8B??8E8)"B#>%53'$;FB7C?G?,!*.F?0#F<@?"8?6<*&774C.&:+9D&/BA5)"%>C3:$G57,!"+-9H:/6:?$/!6G+H/98A'-7HB0@!";#770'9(BH<%=',@(5G*H/9G.;#+')'+8%F9@9"A?46FG/FB"%3B$+<4.HC)#479%.+:D4/F%A"?<;A&7A'H%H9(B7%!.
@r6663
ACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTNGTTT
+
#F?3$>*+.E+8ED,49!37@16?F)<81/@594>G7@%/=096H92-3,)"E1>"E"D-1;B/@-H>0BA*6'E8H:6-,)7&**
@r6664
ACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCNACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCNGCA
+
2:4?0"81F#1%#2)$2DDG=/!*-BBF6C+4-+3./$),FF3$+2B+(,>%"<2+A3A-C)&/9(:/A<"-8$H16#"H*7HC1D>91$=:%8,60E<,('>)DH:483!++F2C*=C8C719?:&F(-7A4'CB*1<-$E0
@r6665
GNGAANNTCGTCAACGGAAACAGTTACGCCGATCCNGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCGGTGACGACTGCGGTTATA
+
##"&&&!'+('$#((&#+%"*$%!($&'')&#+!!))(!%()#%+!#"(***+&')#)"+)&)&')+'+)*$*++%&#$!*$)!$+!')"!+)'"*$'$&(*)%(+(*&'%"!*+#+)"$"'))(+()#+#(!!!#(%")#&!'&+)&#&%&+&%+(+&$(#'"#&)!)(()""'#+$)'#)%!(*%%'!")%)++*+*!)'&$$$
@r6666
AATNCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGTAATGTT
+
*$)+(&'+++&#(#+()(('!''%*%''&'%&$%&"''&''(")!)*(&"%)'#()%!+$&#!"$!'
@r6667
CTCCATNGGGGCAGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCTAGCATCTTCATCTGCTCCATCACGCTGTAAAACACA
+
$)$#*"*)!%*)"+"%$!$)#%$$)!"#'')+)*%#'!'&+&)$!&#"')+)&*)%%+##)$$)%'%!("&)%$)"!*'(%#'&""'!#)&&(#)()'+!($!
@r6668
AACNTTCTGCAGTGTATGCAGTATNTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGNCA
+
#(),--4"$&23%;56B&>16-;B=$/?B(H6+,,B2A6>756=78,.F-$$)1B,;:8,>-1F-*(;F,(#A2/8%8<;"$3;6,'25
@r6669
ACCTTANGACGTNGGCGGACGGAACGATATCTGATGGCCACGGNAGCCGCG
+
!&)&%'!*(##)#)"(&(+"#!$*"+%++*%'"#*)$!%"(+"&!*&)%%%
@r6670
TGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGA
+
H%*<;;5?F.?$9D%27)0661CA7#=70)94.%<0"F=<<B)%-9/&4(>3"/4&</6H&)<;30#E870;>3%HF
@r6671
TAACGTGCTGCGGCTGGCTGGTGAACNTCCGATAGTCCGGGTGTTGAATGATTTCCNGTTGCTACCNAT
+
%'&++$%'"&))!%*%&+$"!'"*!+#%!$$(*#&#&#!!$%&'#+'''""(+$#)!&'#(+**#''$&
@r6672
CGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTC
+
2>=-;,3B8=-0-DF24@10&18!'&&A=E)5DAE;29=6D.<>?E,F4)+26A?=-C/A<-5E+9?4?13G5886/CB.:D":7?>"0=/@:G.CF9=B;9;H2D9$&/'B.-=:"
@r6673
TTGACACANNNTTNNGCTNGNNCGTTTNTGNATTTCNANANNGTTGNANANNNNNNNNGNGGGNGAN
+
!""$"""#!##!#!!""##$#$!#!""!$###!$$"!#"#!"$"$$!!$#""###""!""$$"!$""
@r6674
NNCGCCTNCCGTTATTGCATTCTGGCNAGGCCGCGCTCTGTCATTTCNNCTG
+
%&)+""+'!*))#&$$"*)(*&*!+&(*)$'!($&+)#!%##&)+!)("$'&
@r6675
GAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGA
+
'=H>?0371'E,4='D;/9%(3@!?+5:C9&:<F1".%#085H,E;77>@,(!2#->?7"/24(:E:*.!G08:3#
@r6676
CACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGANCGGCGCACCTTGTGCTGTTTTGGTTCGTCAGTGCCGAATCACGCCGCAATNTACAGCGGCGACGGCGAGCTGCTGCAC
+
+$(+'%$(!"'")%'('%&&$&#)+!!&&+"++'()($+*!$#%$!##")!+("""!)(+!*!&'+$)&#%'"!")")!*!%$!*&'"*#$))""'))!&*!!$+"'+)")+++#")'("%'#"(#+"+!+)%%)#!
@r6677
GCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGNTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGNTGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTT
+
D"5,6/450>H<%?E>;(9!?67"0@(D>/&":;$?21$@"4(F<"2<E&,H3.D7.DC/&HF;(6(H#C58?2%>'%#+:?.H;)**B;H!0C=!0%58G2?E6B!="(+$!C1=#1%*412="<44@6<B39=CA8H#,EC>+3=EEHA8!%F!9>B
@r6678
ATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGANCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCNCTTT
+
@%EA5?/5D1?<*,!631=;1*36#C40G$!,3B(,H4=/C*1A*>2!$$-0;16=4#%@>G4=>3"G71EC)=")9<!$>B5*!FAG!/8E("@)!8%:*E/G:*DE.0#6$)#7D=":@A"@20(!)$D+)8('C;*4*B2-FF.$+5E=::5&0>)E(/@!2
@r6679
NGNGGNTNNGNNNNNNNNNCANTCANNNNNGNNTGNACGNNGNAACAANNNTNTCGN
+
$#$#$"$###!!!!"!!#!#"!$""""!"!$"#$$""#!##$"#""$$"#$$!$$"$
@r6680
GACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCAT
+
4EF<5HEH>1%9F.D*)#6&E4'G2&H(-$,!(=+976/%
@r6681
ACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAA
+
/7."<D71,9-*4H!26G=G:+E*6)F,4@A>"%CC2D@2+8)B"5+/@>#)"
@r6682
AGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAACCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGA
+
2$5G.8C9<39.0+?*H=C9"(:2B;;34@!"-&8/09G2*'+&-!F)/=.1!+B@<EB0?<A19EF$G85.;@7A7?0F?A"B>7/<&6#2)"75:=)4@7>G<,54A"3)B5!9B+:%H=#+.-DG1$E4%*5(7$9<,&7%D"/+7&H/#@1D!<8==27#HE>)'G@/+$:61;4!,&&"
@r6683
TGCNTGGNATCTNTANCNACGCCACGGNAANNGNGTATCTNNNNCAAATTCCGGGACTGGTAAAC
+
%#)&)*#%)!$%!&!&)!$$!)*'&&($!($#'&%$*$!)&'&"*#)+#!%+%")#)##("*&+(
@r6684
ACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCANCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTG
+
H=E5BD/&F*()/@9#+#,(521?7<&8?8(!5+C(E-CD7<0./B>H;?#E52%?@"'HCBA$D9BE)::9@/8:B=B/<9/;*,@>"#@/8/-E/E=;7%?FC(B<2=#"C43F,(B#6A53=576&#A#>@)6%>1$-5FF"/*@C=H3#2D#>8$"GHF?=E%("5@'&C+?/F?
@r6685
NCANGAANGAGNCAGCTGATGCTAAAGCTGAAAATGATGCTCTGNGTGANGATGTTGCCGCTGGTCGTCGTCGGTTNCACATCAAGGCAGTGTGTNAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTNTTTCACCCT
+
")""&&&$*)!##%+&"#)*%('&'$&)!$'%**$*$)!%!##("##$#&&"'"#&'')%#!))+&)!)$'%*()*(&$!%&$%'"!"*("(+%)#&'%'$')+*+(*$%)(+#"$)$)("'%$%$&$#*+*)&"(!&!((+('#"&+$&+%)(!"#"$"#"$&#&#'))+"#!((!"%"+$+#%'#
@r6686
TTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGNACTGACTGGTCGCAGTACTGGNCGATGACATNCAGCGC
+
@&(EA/:/G3@"7.(&C=+/(95#+1C*)-FH)<'/<G*/7+>H+1G3,A;(:&B&@F>5>,C!9,A9(2&5&@/*&>*F
@r6687
NGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTGGCTACTGCGCTGGCCCTG
+
"<)<-CB??<?)@6B"F2=/%@@C0G4D*H:>0$>8B40+5>27>'"A.6!;/5#-"',:C5=@-AC+!&A6A$?A#B8>8-,88D#/,?!B&C
@r6688
CCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACG
+
;A&/>F:'-2?F-#%9?(8-!4(1!!5=:70-9;!D?0H1.)A*?BD>C?G)G#"/@:5<8:0$5FE=3>10F;'+19>7A>'.1-A+,&,%B/932$$%)D
@r6689
CAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGNCGGGGCNGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTCCCGGCGATGAAGCCGGGGCATTGCAGGCG
+
6#5)EE?,(971/C8&+4<-)<F52"H@!+9$3#9>HG4?:'@(6*!@8F;,'*><:#&E=""74G4.A$AD3C,=C",G8-A86:857GC16E=>'(/'%36'(G"2?$D::AB(:D'"'G158/,4A-A;?=A2><!7.?A/(DE)C?@
@r6690
TGAAAGGAGCAAGTGNATGACGGGCAAAGAGGCAATTATTCATTACCTG
+
7:!"GB--:#?%,GB(7H#/;FA/G54C>5'!D#>=!A%.@C>"#+&?)
@r6691
TGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTTCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGC
+
B*>,<D"")+/:@#7915868G62>H?,+$:G8'G+8@%?2?=%4FCH2EF<G6?"3);.7*==.?4(E*7=-'#7?'(G!=%0>"6100)>($*2?+8"D+9
@r6692
ACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTA
+
.$2%H#<+%:4C-86F80.&>")#/A",/9C*>D+.*32D(
@r6693
GTCAGGTGNGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTT
+
=&74,'9,>4/?*">5C9F=1"7(4H73#-6AB+G>,!AE*F1>*G7,>"*/+>!B3G?:0C@2*!B:1"5AD)8<-6B$*2-;%4-0-@C19%.1!/>#$(&C:5:B++B<&
@r6694
TAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGANAGCCCACATGGCATTCCACTTATCACTGGCATCCTT
+
$D70'33GA56C;9;%/-G6G"6!<31-#!$11+,5@,&B:/=H!C(>6,6CG'.C%!-<A)CA?4A=&4%
@r6695
GCTGTCCCACAATATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAAC
+
$6/H%2":60&":.;AF!*0GFBB$'E4H6*FH//8G-=D?&3H+G1C,/90>C9+,+2!G<::9D,--D@*&A=<G8B#:%1)*;D=&G?47?+#00&<&84C(08D0>:<.>
@r6696
NTTGCGGNNGTGGNACCCNCCGAGTGAAAGTGTGGATGCANCCCTGTTGCCCAACTTTAC
+
")((&*#%&$)+$#!#+*##*%$*!+)!*+$)*$*+!'*+'!!$()+%*+!+&+#)'%"%
@r6697
GGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAG
+
8%)GD6(/D,E1C=12F+3**.,8+#":%=-31!-/3@F'.1!!<&$,EB&/A&6;4A9?H*(*GB&D!//9G6C
@r6698
AGTAGCACGCAGACTGAANTGTAGTCGCGGTACGGTCAGAAAATACGTTGATGAT
+
1)4+,'C@")G--26+=*%">*@,+(=953+*#D<!0&(D-F8"4$"!-/H;7'=
@r6699
CTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTC
+
%(*+(&+(%!&+!$)"*%#"#')%###"(''!!+&%&!$)
@r6700
CGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCATCAAAATCATNAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGGAAAAACGTCCGANACGAATGCC
+
::F'B&7;?5?2%1&FH=*$%2/2>7A=#9:)6G#%;-=.D,>?&+?DDE#5&76>@6@*')HE/A88C,F(G.*.!282?;>4352@&22C+B.'E3AF88E1%B6.'!&A@,-753B>+3%B<3?&H#+D=%=<274C+4(14=*H
@r6701
NCCTGACCTACCCAGAAATTTTCCTCACCGATNGTCAGNGTGTCTCNANGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGG
+
("!))&$++%$(+'!+'(#!$+&!!)"""'*%+%!*(+"&"&%)'"'$')*#*)&*+(++"&*)%##!#%#%*%"$$$)!)"'(+"(
@r6702
CTNNTCGTNACATTTTAGCCGCGGCCTGATTTAAGCTGGTTACTGTTGCGCCTGTTAG
+
)"!'!$&%!%+!%%*&)#!!&(%+%(!&#*%*)+$"('(#'$)'(%*'(%)$(($''%
@r6703
AGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACCTTTCAGCAATACAGGGAAAATCTTG
+
-!2B";+=0=H&$7=.F-2CE"D."H$!0*(-'+@8E*:6$@F2>%B>D@)0*'#E40//,0$05
@r6704
TAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTANGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAG
+
,AAE&=;*A':-7H=;G=@:2!378.-,4-@,;"H?/@@+:&>41!:'&-%E3G$<)DE8-6%@'8+&=1;B(23D)'(-F89-9EC>7H@/#A82F:/+,=0=(*9E>F=2%:<)@+"G+=C#,)*
@r6705
GNNTNTGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCNATTTTT
+
*&!(!$+("&(%'"!'"*)#$(&&(&!(""(%$&+(#++%"%*'$$%*%'"(+$%'"&+*")#%!("
@r6706
GTCCGCATCCTGAATGNAGCCATAGGTGCGCAGACCGCGTGCCTGAGCGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGAC
+
47F.::F7>,?(F)54F:<37@&>$"/%F'04-C3(=+7.-$.D/7?5,>5*@1#F?/A)F":986"'E"3-;+4<!$50!8CCF=0>C7D6D0D$:-"C@*G4C:1,H%@:EE*791%2*5/52A
@r6707
TCCGCATAAACGTTTCCATCAGCGTTTATAGTTAAAAAAATCATTCGGCCTGCATGAATGGCGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCG
+
&+GB:$94/-:D16@?58*"+?9!3-'F3&37G*D$+G??*#'61'!E,?"G7,&=9"!!-/=5+?1%-C7%,#<505E2#9B<4?F5"41A(;!-5D$3%(<B-.72*DAA+F6!776
@r6708
AAATGCTTACGATAACGTAANGNATTATTACTATGTAAACACCAGGCATGATTCCGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTNTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCNGCATTGGTGAC
+
H+?2"7>7DH7<=:3541580>E2/!B)5'&%A4<+C6!1*F!C<("B$:@.6)D.@*?B&F7)*!&=9--30'->C>3A#AA-&F,4E@;+!4925/24H/<B0?)ED7"1:3#0$.?#4/)85-D;>)3"='6:6"#6/(#(!/%94AA+8B@E3#-*:D-3/E0G3)0=4%1'F+$H4?(+
@r6709
GGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGNTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAG
+
@C?-"4?(:/@H"5H8$==4$D/;=H:C=2H/'<0#?:>(3*?9.G3021&">"C;#<>"$D'<B4*0@CEH"(A=A:1=""+4
@r6710
CTTNGCGCTGTGCGTCCGNATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTNTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACANCGCTTTGCC
+
*%)"&*+($!#&+")*+!%%)&*&)'%)#++"&"*#+""&)($$+#&&%)##$"!*$"%!'(+##(!)*$%!!!'!*()**)%"#)'%($+!''&("%)'((*"%!'#+)%+&%$##)+*$"$+$&!!+!$&&*)+"+(!)(''&+!%%()#"$&)$$'&$'(+*($$$)*%'+$!!!+*+!*"
@r6711
CCGTGCCGTTCCACTTCTTATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGAT
+
#$+"*+$!!()'!&(!%#*!"(+!%*"!)**"#)*')'$"&($++()%%+!&!')("#%("$&)#%#'&"""(&&%*%%*$&&"(&*&#($&)#%"*+!)"'+!%*%!%!#*!#)()+!$!!!"!&%%%!%'(!(&$""%%
@r6712
GCTGGTATCAGGTACGGATTGCCGGGCGGGNCGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATCGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGNCAGCCATTGGNGNCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGAACCGAAAGCCAGAACTCCACGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTGTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGT
+
1>F(H?7::,(0/51F$,D@:>H3B"7<CB9GG,8140;0@#!H&F5)%AE@=/0(E5*#3-<.16+,&#2+H;4<-$;&FB?F=58;F5%+E#2+%6">9)GE-3<$!*<E;<5=/:9?.&FDB<-074<AED$2C-6:<:/56E2#C"41'08<+$%C)E5$*$G53D1;.'*H14B2+)4E-%"<-&-H<.&@)&42*?6G!;=,B1&=.5,(/#AA4G(5!=(03HE*&"=0F>'=<5'H-E;,%<:GB$F&6'$!3))*+&E=EF(@-A:-?A(!;-4<;+/);45(E*>,+:HD1?HE%!:$9'4D/:C")(DF++#8*H:&336.HBH*G29<,6,!&C50@B"='08F:H.0#)>7(H20;(/1?;.0C*,.C>&@G.BG+?*C%?.#"-)87@*E%7E*ED8,:C5-&H<8"AH07H
@r6713
CGANANGNGNATNTNNNACTNGNNTCCTNGTNGNCNNNCTTNNNNGNTGCTTATCCATNTNCTGGNTA
+
!#$#"!#!$$$"#"!"!#$$$$#!$!$!$#!"#!!"!"""#!$$##!#!$$#"#"!#"!"!"##$$!#
@r6714
AGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAA
+
5&7.0=$:B0E07(@4@51=(G)8=8@,C7>58(B0=B<256'#;;2D0H1%3
@r6715
AAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATG
+
F"#95.'%:8F%!6(;-%4C+G0"+'@;993#?),C5,<7G4)$@E9>'5&1;)=8/%B'H!/4-1H.29:%*G:;<E;"4-.(=(1=>;D(5""+G-4A$9/6DB2E*66G;H1($2?=
@r6716
GACTCCTTTTTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACNATGAATCCGTCCGTACGCCAGTCGCCACCAG
+
:+C5#:'116:AA<%"#H9BCED#CF5,-)H@/5(3AD'(-*=,.9-%50(1GCD";(9.,<5%4+F/2?!:2HD0'?((G:(=)3C+4-+,)%#7'@2%.A+H+B4#+/0$B*&CG0#(%0!39?C@
@r6717
CAGTGTGGGGGTGATNGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTG
+
:<<))%)+1).=%(-G!:&,$21'F@,H-F2/'8$(+=.?0)C:1)&-8&,0GB?")7"=6=1"4.044/<(='@6%H646$47<&E.&8%"!
@r6718
GACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGG
+
*+')&&*!!#!"#)(&+)'#'%)&!&)%"$!'&(#&##$%+"+'*&!*%%'$+(+*&&('*%+'%"(!"!"!)*"("#*!*+#$)%)$*)&+*#(!((!#$
@r6719
CAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAG
+
80C;9;CB78@E8%=C9%%)D*'$2'%;)($2F,71!:%D06A:,,G"G'BA<C186E-+:F,F).+G330"#.(AHB&#F%3'"FB:#G!&4-F;*%2=,#)C;@B052H0F9A58BH3#=*:6">(G/>C;81B<%&>*C?
@r6720
TGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGC
+
5>A8$6:8='1('..9)!6*&)<('6)+?@2E<73*AG8FF0/A%65%4>G%+
@r6721
CACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGNTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATCAACGCTGCCCCTTTTTNCGACACCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCT
+
E)!H=$"**D"!2'??0$B+*)@)2DA7B-<<=*:4.@2/BEF;"9A(H!8E8?;-*$=:5=.6GB+-5(?1+C=0*6=>!E=,5A+#,">!&+''@,%1%DD51'!6.5(EA7C+3F&&F7'A+G32:=-,/9)<A;"'4G8<,7:)C102*,BE--C(GH!6G@='."H$+2>:#>!)9;+'#%-%=%9'6DB7;>.G:"&B;=6
@r6722
ACNCCTTATTCACCCCACAAAAAAGCCCACCGGTNCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACTCCAGTCGCCNCCAG
+
#)'++#+("#%($$%($()$#!'(#*)(#$!*!"*%(&"*&'$'$(!&#""+(!!'"%#$#(+*)&"+(&&'"'%'#$$*$++#&+(('$+"%'!'#+)'"!#''($&$(*+)+#!*"%+)&#$%&*
@r6723
CCNAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGNCACATGCTGCACGGCGGTGATG
+
!("(&%$+*$)*&+($!&%%()!$&(''+))$&"!'#'%#%#"!!+%"++(&)(#*&$'*)!"
@r6724
CAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACT
+
-=52"G.ED*<'45$'&8."C2.E&4G<!04AB>@;))0*1<&5!+8D,H=)E?H/:83
@r6725
ACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTAC
+
24$@,;0@<35A:+-'2#G(#'4D762,2/;H:4AH9+#7)02$HD5FDA1B,'(4CC
@r6726
TTCCCGTTGGTGGGATGCCTACCGTAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAG
+
(BA9F9C@BH/F0"*E@'@"3/",49B>)37891+$%,A*36-=0!7%*8>B5'20;:06A,/?AAF(;7(3#FD79>,0&8H@!$#?@A%5;B3)CEEEA<*#0<7-'%)G6++@($?.;'@)-E&:(,D;<99.!9/31?)7=G*#:/($<$+G4@-8B'G4),)BHD62#2-+@-3H99%%,D9;0:30!'/)$92
@r6727
TGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTNTGCTGGTT
+
((7(!+/,-5-@6@6;C.,4C',B/$1:FE;*E77E4-$(#9&C$01$43
@r6728
TTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTCTTCTGCTCTGAC
+
,(02F))%88#0>,$+1H1'D1';,D0=E9!*@)6B@+&%1-#,D45A3A(-@8F'=D.C%&*F%5E&E@8/,6%+B23#;#D(H;#7
@r6729
TAACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGNGC
+
*&:*GDE3&.9(3>E-<1=F*&*;GC;4+'*'H5FA?"#'2/?A:(("%+E=F"A19!)G=.8%BHG0949<>/028>0'#:;A?:,%F0E3,HD!02H*,
@r6730
GGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGA
+
:+4>@(+9=H<7D=4**'1DAAE->+*+;&@#;#0*./9.<+88.
@r6731
GGCTCGCCGACTCTTCACGATTATCGACTCACTGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATATTGCAGACCTCTCTGCCTGCGATGGTTGG
+
14:8!H*B3;-()166?>A&B,3D4.B!<**GGBH36!!&46".'9-?:$63(.B@'38&2(1D/C)D;3D,*,(/:>0;)#7,<%,E90650<>*45<!&F7&'-$/4G:@=+A")@*)4;0(+G:3H#)?%2$5D43-D(,G'A4?+
@r6732
GCACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGG
+
%-F.?@$0'A4'9,:E$#$'*-*)4"3&79G+!F:HB*0&E#+<'?<.%)3H.>9:?9A&*-A6D"6*%@5CFE+1?2*6*5!136+:>C.#0@2E%)+4E
@r6733
AATGCAAAGAGATTNTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAA
+
8:*+"9HG=1,A%$%'A%=4@9H.3C+<H(E:%589!!CCA4D!;8,G>.21=
@r6734
TTCNTTCGCCAAAAAGCCCGATGATGAGCNACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGT
+
74C@)7<<G***#2$CBE;?/'%#33$(4<)*!2+&!9A+D23C!67#';D/%A#72H/,8=A1%F6(H1G<,-'@
@r6735
GTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCNCCACCANAGCTTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTGGGGATTAGCATCGTCNCAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTT
+
E':<992"'9?!?9F%9CG2B-$-<('H3'*"::?-G%C+"D5=;0+E<*/8E@'$A/C-32B$7.,&1HH/&7?92F>D4."$,C=@4<6?'CBE=GE7/8.G,7F9E@+:),AA-?9H$:A(.).#&4.<)C*-/@4;@02956')>+(;?*=19)&
@r6736
GAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAA
+
AE399#B!=6$!$6BC7GH@"$/E?%3G->,@5-!B*,.F*GE6$@63A$AH%H<.95""?A=+A.1;6%<0B<(%H/8-5F+?(79#.:%AD:D7#02>'97&B7.
@r6737
NTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCNTTTCTGTTC
+
%=&,';1>=5"3!.!*:+3)H#?5G</8#"0/41A91+9,,#@60BF?5
@r6738
TAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGC
+
-">!+?(%.(*$G-@0H27GE'+,""1H29)%*ED74642;)GDH.B)(8-'EE4=A?
@r6739
ATCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAN
+
"#25$8)%#B(;:'FA0?2-.6;49C'$,$C:0E2G6"*4H+/$>.(7A@5($9:'9=$?F-#>5>0A')#%G9(!F+(<,/E@'$2E&%5,.,(F4"0./@4F3*D&.3.<+BC/1*9B0*E9?
@r6740
AAAACCCACGTTGAGCNGACTATTCGTGATNTTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGC
+
DG/528'<HF@5B1E6"*/C.:1@D5.003,=(@4B(>5D>'4655+BD)3&3*.A@7G(G?'8$/69)%2+)19@99"0;)5GE!:D$'9,96>0/%?=;6"$BG=2/?4/=DE
@r6741
CAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGCAAGCACTTCCTGCTCAA
+
1197G(C8C.#GF0253G77H=D!F,9D7<?(?9H0!A7?#,2&DA0.+EB7,:D(57??==F3F;><06,%;:1
@r6742
NNAGAATTCGGCCTTTCCGGCATTCACAGTGTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCC
+
%"H77;C:+:@'9D"&46";$E')AE=$/3@FF8:=<&,3D;8(B%B1*E''(""14DF$?@:3EEC+F"'0%),3?6.3$3#F%4=EDC57@D$1.>5
@r6743
TATGAGCAACGTGTTAGCAGAGCCAAGCCACAACNCTAATTTTAATACATAATGCNTGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTGTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCNTCTAGCAGGCAACCTATCAAAAT
+
2;*GH#;F#%A8C*3)6HG.8)0%0?'/19551D(041EB#?63C*F<,@?2*%G8.91#44A8>F/D?<$@;=,)88<$7=GF4>4#&#=>,1/$),(2A0,?,(/4FG>(#2<#"81:1@6:<*?"2/(02H:E(";*3!A9!:7:4C:9;'3-:7$>:3!H('(+FG9.@)B6-&2A6A02;'A58!5B4'(+64H':&F9<&-FB86$=D1ACB
@r6744
GGCGCAGAAGGCTTACGAACGGCTGCAGNCGCCGCTGGAAAANA
+
29/"$D5*(=793,&/EA$!$E(,+7#+E-=*CFF2<=1;;=*)
@r6745
CACGATGGCCTCTTNTTCCGGCACATCCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTC
+
:9&1.H3FF<33+7,-<19C-4,*>5#=7G4-$@C/6AC@";7",<10B(3C:%B7(/.F&%%:"7
@r6746
AANAGTTAGTCAGACTTGCACAAAAGAAATTACCTNCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGT
+
5$D0"F+#8)H3$7C9527C$/EF9@(2(8:+A$2=:4+1,43?>>%DFDB7?>6<#GH'3%G@E3H$')>11E$&&(*+;7
@r6747
CCTGAAGGACCGCCATAATNCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATA
+
-$#'D)-'.?7:#8%F#'3-%G-G$A";!2D+#D3%)*B#,%?#DED5%+9+.H5%*6@+;=0<37(,7@G#)=-=(2.%">(@/E
@r6748
TCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGANGATTGCCGCCGNTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCNGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAAT
+
&HH=-:;EB($45$4885>9G7A>H&012B,"4/=E1+AADG/6=51$1G,.$DD/<>"2E6"H.ACE35?'<<E&G-;B)9%,A-A%6+F$)29:+<""$'/10>6:B5.>*.3.3E%%20/GA>3)E#2$01'2&!"!+:@E/8&9?D(/"/"253<;'/*3F#>FD>B34)32%!6?C1GB@84GF!F?,</.C19?H+
@r6749
AAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGT
+
)(+#'+%)!*%"'#"$!+!%&%!)+$)*%&%!'"'*%')$#!%)+)*)&)%#'+)+&"(#+#'#***&%*$
@r6750
NGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTG
+
%15&>8)<$-5#>)!<:(-BB?A7(":E#'@$:D/&D0(>C7!C)9'&334>%H<>+7G*&*&!?@5@B4DB.0C4*'C'18C*=9#H
@r6751
TCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAANCCATCGTTGAGTCAAATTTACCCAATTTTAT
+
7HB13-<@,%:=#=4?G$3?$/(-0&5(F8D>)#(*9A*3:B8#DG2&G62AB<9F:F<(+?G.A38')!'6?2(;?A*."64%%@3?A""6$;>$'HG5A;.@6GG
@r6752
ATGTCTTTTTCCGTCNCCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCC
+
,/B":8@BF")HH+/1'$G>3'E#/.?#64(4DB/.8-,G()4@:&4,=894#>>.%B-#2G?.0*&GG$;'2D.0FH
@r6753
ATNCGTCTACGGAAAGCCGCTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAA
+
.1=04G./GDH:/#A.5,>+EA*4,>:B@DHH8C$-&CG-G$E.B?H#!>,3/:BB8-9;;"BCD=5!52
@r6754
AATGNAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAATAANAACATCTCAGANTGGTGCATCCCTCAAACGAG
+
94%>$+B9;F#313-70/2;#;=HA9<(HB*A:&)7-?1!56-HG?=+%6*F8>'':'1.!?9<B+0$$>D4A==E+$-0B=E$#%3G4=@.GA%H1619>".3
@r6755
TGCTCCGGATCGGCCTAACTGTTTCCGTTGACGAAGTTCACCGTATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGA
+
6A,H.%B/2!)"@8938(B2,0:'7!FEHD&F203&04%G'%?,HH1%A5>&D6>6++H.&&A6:=>8>G#**8<-H-"0?+#*E3"39C@H#E2A,91$<D-2@$G607<1!$1;?CA#>=;B=>$8:"/E-$3,,<*C6;(
@r6756
CCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCNGGGATTTCATGAAGTTCCGGCTCNGTGGTTTCGAGGCCATAAA
+
"#+("%)&$$**'*+!!+$')!(#!!"#*&(#+'&$()'#%%)!$&!#*(+!&$&+'"(+)%$(&$+'**))'#%&)#$)#%&$+()$(''#%'(***$)")%$""*'"+!%!('*)$!%$$!%%+'*"%'!+$#)&%'"$"#
@r6757
TTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGNTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTNTCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCNCCAGCGCCAGTTGCATG
+
+$!$)$$&*)&%%$&(''*%*+&$*&+%)'!#&%")(#)"'!%&!%*#&($%!*"'!+!'#!+*""'%)&+"!'*$+$%)$")*%"$")!*&%(%#(+$+!#!!$**!"*('&'%+(*$+)$%+(#)%$!&%("''*%*+$'##"+#*))&")!(!"$+)(!(*)$$+(("&)&(")!)+)&$"%$&*("++"&'"(&'*('&+#'!##'!))*"#%!*&'$%#+&$#!%$)('(+*%%('*$&*'!&*"*%+&'()"$#(''""#*&#($!&%)%%#((')%%#%!')*"+(!)*'((*#*''"+)))'!""'*'$&!+)&+&('+)'"%#!$*'&""##!!*%'"&*'"+!%"(()*)!"'*&)"++)&'$((&!+$(*#*+$(')'&*""%&!)+)'(#'#"#'!)%&&!')"))%()))$(
@r6758
CGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCG
+
%0&7&6AE6,1.5F-5'605(('%FF3<FB=?87.FH#)C)BCB"9+,EH$..*C$9?'49=6@AF#
@r6759
GAAACAGGCTNTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTANACC
+
:"92HA,-G=81':+*?$(<9<$9.#<3>?FC5/9>@0$EE"C<?(342@.F>+842<%,.;=0@1$/!%,<8-@,'$:"0<<@25>
@r6760
CGGCAAGCATAAGCACACNGAATATGAAGCCCGCTGCCAGAAAAATNCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGANAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCT
+
:&E<9EG+HG.--2','3BG%B-1G$&)!:0--H<53*D>?5&DC<06&/#2A2G?',2!$;4@@G=<'!8:7<BHBGC#;%C)2!=9B6&1'#4/;5:/9E+$)=<)$<4?=/#/6D/'1B(5HG"=$%6A*B>1=C!1?!><-#;EF0.(,8F%@03'G0G,5*:5,&"$9+38'+9+10G@>.G&>D+&:@15F3H44
@r6761
AGTGTGGGGNTGATGGCTTCCCTGGNGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGAT
+
)$+##*'(&%+$'*#!#!&"%&$'$$(&%')(*'&%%+*"%"$+)""'&%$()+!("%(
@r6762
GAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTG
+
CD':1D"1'57952+8+.GD/H5,0!*<06H@349>!:<!&;,=&&#2,.==6>;65C(1A%0:50*!(9;!'/$+.EG:=)@7D(0F@.68:6?@EE9#..D3#""FC0A0#F);<*9)4'4->!9*1%H*@<+:?AH;)84-67G:$6,0&)32#@#4
@r6763
CTTCCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCT
+
"&*!+'("&")"#!$!#()&(")&#!'$$%$!(!))'*+#*$("%&**+)$'%)+""($*"!*&(&#*'
@r6764
GNCANNTTANTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACNTCTTTACCTGCCCGTCGC
+
'!&)#"""'&%+(#&)"$*#$"%%'('*++(+&%')"+')!!$!('(*#*"&")+#('%(&*"&##&&
@r6765
GATGGGGGCCGGGTGAGGAAAGCTGGCTTATTGACCGGCAGATTATTATGGGCCGCCAGGACGATNAACAGACGCTGCTGCGTGT
+
DD@8G.()"%H*7#)!?:-(<!21-#ADGB,33-!8,.%AG?B58<!,-)=AH,E9&&>G4#/9:B';,A:""53*"';C4:48/
@r6766
GCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCAC
+
3=+00&+0$")':DA/;12;G/"*>./$/(B.:1'2'&3E,*>FF(B>+64C7(,0/>/?@:"*G
@r6767
ANACNGANTCGGTATGCCTGCATTCTGCGGTAAGCACGAACTCAGCCAGNACGACAAACAAAAGGCTATCAACTATC
+
)!$*#&&+!%#((&#$$"%%("$!&#&+!'$%)#!%)!#&(!&$#"%$&#)%"&(+%%)&!+'('*!!*+$%!)!"*
@r6768
NATNGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGNCNGTAA
+
!!)#)!$*('+&&*(*&%&'+*%$$%'+##%%""""+**+$!+'$*$#"('!("
@r6769
GGTCCNAANGNCCCGANCNACGGAAACCACATACCGCTTCACGCAACTGGCGCCGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGC
+
#($"%&%''())'*#$$#(#+')"##&"#%("%)"*$#%%!'##"+$"*"!$#$*#($%$(!(+'%"$&"!**##&%#&*!%$(*'&'!)%)%'$*#%
@r6770
TACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGT
+
9G615%.**(9'8$?;.D5/5"!$40FFA6=72F3#F'(<1F8)22H#*754.8$@D@H18>%)6
@r6771
GTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGATGTGGCTTGGCTCTGCT
+
.H16F5E#:1&1G1:#D850?59CF4)5DA)-'D?+5%51D.>;A:*G+A!92&2?:<!2.81E/;9:,9*+9/A+H@#3$%5$DFB8F,>=/H)/CH1'-#<-,<7772E#+?C9%&17/
@r6772
CAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGC
+
7,&!B1@B/6?>@C,/%*".208!:&D))!@1-#3/1F4%.G@8'?:@<%2C>02E=:.BA@BC&@4.%0D.#89729),;3D.:
@r6773
TTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCT
+
;.@+'G"G7*7D!6*49C/B'6,D9,(G:FB30$'"$A:GD.--2=;C3$=%+GDA5"5'0FEFA#$6E:B!7/'%7=+&2E,-=4+2#1G;)&B"@;6!-=@*,?5$:C9.(:>"+#$(@GD%%4'6"H6)"-C)%6&1#7,.'"0'6
@r6774
CAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGNAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCG
+
*?+#0@C%A,CB=D09653@>8-F0,"5@4/#A%H@C"%"H@8DE@$HE3/)/,;&<,;2,3)6947-<:>?:D=-5($$DAA'A@DF08+CBG?&B4'&#A0=7:8929)=F#19$:A949=46%@4$6?CA8)E;8"(:EF4?#F0!<)+?9G,/,C'G+?,
@r6775
TCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCNATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCA
+
1):%@50,G,H?:*3)7"AC4%BD1F)@!+3%63.+=E="=!..C1B/#66;CC1?+3=A,0?%DG579*2&0%5?FD6#D)@1*E,67:/&/F;:#,67)H?<FD*9!&>,EA"
@r6776
CTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAG
+
"A53::E%4'#.%9:7'A@:#E<!/<BDH/B440:-!53+C4:B2E(%.6$F>8'%,F%E7E8?0;H!BD3595@$,0H(!/=4-1?*?(06AF#-&8@%"E=AG3(">AH7H'H(,4/2+,$!,A@0ADG:6#HE1)(+
@r6777
TCAACGGCATCCACGAAGGCGACAGAGGCTGCGGNAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCATAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGNCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGC
+
2&)4?.382#%AC2,D6+'($E&221/G"1(3,%?0+<'A1)*&FF&%3)*)(=.%ED51:>G"8/)7369-2-E0#<G=!?+F$35)GC?5;E,B5B.2(D2><?$#;E!/14E(;A>@9#8%@#5HF?&%)G;!-;</7F*B%E14@&+@=0#0-;:81:(1C*"%H%B$'!2D(:A;@+;#=H'%B>2F0C83%F40(5@3>E$?&-BDC:+H*
@r6778
AAGTTAAACGATGCTGATTGCCGTTCCGGCNAACGCGGTCAGTTTTTTCGTCTCGTCGCTGGNAGNCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAAC
+
D1:FE7:27E%B(&6&B6.G/D=H9"7+-;4@6,/-%33&5#/5/&(2.E%)3,';<-F=?#1<*$,./3BG)H(GBAF)HA0-03#BD4<*-9,'B>)1?G')61#'F$&=$,7*(?GA6E+5$(<3<7ACBH,7-/C(645*H;5C$,182-,AGB>)H'
@r6779
CTGCCTCTTTTGAGGCCNCCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCT
+
8FBD$&5,*G((8CD46:&2+;($/=<=*$)<*"A62"EG6"'<79(?'#=)31?7#5;B,AD>HAG:9)')%7)F-ACC1-4C7<
@r6780
CTGNTTCAGNACTCTGGTATTTTNNTNNCGCTGGGCTTTGTAGGTAATGGCGTTATCACNGT
+
)&'!))'($#%#"))%)%($&)*#$("&'+(*#+(+)##*'$*$"("'++$#(!*"$$(!#%
@r6781
ATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCG
+
/&-5-1&0EHG('?.:A0<?#"'C0*5H%B";C#)#1:/1,37G!?G.%=B<7C2=!*)2D
@r6782
TTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGANCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAANCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGNTAACCGTCCTTTAAAAA
+
B,59+1)4"15-5->#6G(#=1-#*B-,A)#GCD>A>#H)B+(&HB2-HH.D!6(C."&'*$@EE'>#-821H8(%H/FE<>/C>'+01."8E6:#4$+:;(.9-:C@,?=EH>;C*!310>55?>%.2(5A=.842@4A9F)$G/$?;+!E3(CF%34*>2G'<+408;<+2/(;0-&=7!336(97+4CGG$'9G,H**3D5+.#1<*/4;1%9,:G4:+$"A5A9+!.A--'$D1G859-2G*#5((*?'AD%<$>4:+;2CG&?G:?B
@r6783
NATCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTANAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCTATGATAATGA
+
$/@7@?-",',"6!D*0-,18571-&?592*%C"1&0F&B@&!*E2;B'=DH+7%3+$-=F>H$/#;H.A.!$#%%;>+>7&4/-!1H9H8B60+'9".
@r6784
GTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCT
+
>A'C4=@+5!&@=9$';G/'6F*@4%9F2=2(,$7)*0BB:B">027>3G*2FF@.5-=-7:7!B21$
@r6785
TTTCGTGAGCAATGGGTATATGCATATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTT
+
*&+'&&$")%#('#'##&$#&(*"&(""#**)+%$'&$$*")*&(+#!!*(*&)%+#"!"!
@r6786
NCNNTNNNACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGANAGTTGATAGCCTTTTGTTTGTCGTTCTT
+
!$#')(%"($(*+$!(!$)!%+%(%("(&(*"+$!'$*''(!!)(&')&&($"&%(&(')&+'+!'%+"%+&($&+#(#'#)
@r6787
CAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGGTA
+
2$>>431E?E9H0<B8+D%)C8.29'8=AC0!<(+1*+,2/G1/?
@r6788
GGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGNTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTNACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTG
+
6$-$!+1423"2=@=<2:<597.'?=6C4<F8804&3;0<:776+</4>/37H<A$*.396(&AH@):4)F,&A8-+4"&@=($H+861<8:$/;E/D%%!A$/B8/3>E4*?/16HE-)'6+#CF"49?"G?1#8B@,3F24()>&;A/#()<5504'&"G-8)6009@H$C!1''&
@r6789
GATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTNACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCGNGAGGTGTNCGCTTTGGCNCGGACGGGAATGAA
+
&D)?,)D4/("29?2</<!0!F-"3<"0;#57$C9AC+;=B$)2$0"$47"F,;#4.>3H)$00D0$>B<@H+7H#!G4="&.F=E@%(4<G:4)<'HB34#?>49>+E#&)193/BE:9/?304,!5+;92@%)?)E69C#<+#?6=E=+,*665+!*@(8<?4&D,2+BEG+3?>H!#<F.&6G
@r6790
TTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTNGACTTATAAACCTTC
+
B,G/<EF9.3:%*.D9:#4(/(G&H'8#5CAH'2,(3?5B$?3$1);B<B"A
@r6791
GAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCTCGGGCTCT
+
&B6?:)*C..4'>A5F6!4::0"$?A'?.%E"0?H:!).>0=;B4>AD)F86#=6H&'G--C>@?=E'D?8;E7;4#8>+<"3B7B..D573C@7#6/(B)313E>B3*643:G/:@9@D*4,)4&0-=A=
@r6792
AGNTATAGCGTTGCAGTTTTACCACTTTCCTGACANTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGGTTAGCA
+
%*"##$&*#+()!(*+'$''#)+$!%%#*&+'(!)"'!%!'%+($$"%+$)*""&!"%#%!(#'("%)!'"'($("'#**'&%)(#'$+
@r6793
GNTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGG
+
$$4$&//%#((2>7:E+,*BF**+3&!C#%)?2'")@1/!C@?58$F!%/EE/59.F93!#B
@r6794
CTTGGCTTATGCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGGCGCATNGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAG
+
E)9F"3/!FH#/(*B9?(0%+()@2)>>GB$,H/)19D"B5H2!-F:%0+?=3B7'3@#'C9F7-D)?E9(:)2A9H07=6<%'>E*-F!+/5?%1&03B+A@H#&(51<('4C!01DD+:,@!-1"11=&-0.%*-/D!;>DG#C8A<?(.4DG!6B2!E26C>G=
@r6795
CTGCTGCGGCACCTCAACTCCGATTTAATGAAGGCAATATTCACAAGCA
+
<?&B&24G@GDGF$!CH:44)689(->97<%)0*?(":,HE=E#.6'A,
@r6796
NTCCGCCGCGCCCGTTTAATATCCNGATNCGCAGGATGACGCCGGACAGCAACACANCCCAGCGGCAGAACAAAACGCTCTGGTCGTCATACACTGAA
+
'!$*&+"!(+'#()$)"*$'*(""()+!$""%(&&##$&#+%#)$#&&)"#*!'"$&')!%*+*&''&+)((*'%#'%)+)+++&")(*!&'(%%*#*
@r6797
TCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTG
+
F$56.@,9,?A!';D*B).,AC3>89G++9(17#-#GB-$39C8D"A1>:F/>;/&F+1F,>.)&6!!<
@r6798
GCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCC
+
.;%DE&E12-=9(0:1(?:9$B03,-,3@?=.@%(C4D2*>=+2@>09#$
@r6799
ACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCGTGCCCGGTGACGCCAGAGGGAGTGTGTGCTTCGCTGCCATTTGT
+
(+%+*'**)*%'&$$'*)"#*#!%%!"#%(*'""!%"&&**(*))$)&"&*"*'&'$$%%*%$%%!+$'!+'%&*)(*&'&'$+"
@r6800
CGATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCNCCATATT
+
"$+#&$#&'$&#&($$)+&$$!&%#&&'$!!+$$#*!%$(&$)(+%#**
@r6801
GCAAATACACCATGACCGGTGAAGCCTNCGATCCGGTTGNGGTGGATATGGGCCGCAGTGAGGAGAANAACATCACGCAGTNCGGCGGCNCGG
+
BA"!?"D,2(+30:B2%6G..A',-!%*8/C?""6<7(725.!1A/(<D+;!C+"+F>7:,42,:45%B3;GB!B,())G5HAD$+'5'9=47
@r6802
CCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGA
+
AFHBE28.!0,#G(:F4=D2B))B@FEC;0+6)+:<#!$,8=4,9+E>)==>HF/C/"618?D%/$<'6,;.?0D!)3"=6-<*D*B:;40C+$04)1C"$BA.E(G85:3G
@r6803
ACNGNNTTACGNTTTTNATGTCCGCTCCGGCACATAGCAGTCCTAGG
+
((")$"!$$(*$#(*&!&+'&*!!*'+#'*&%!&%*$+)*+!)%$&'
@r6804
AAGGTATTTTATGCGNGCACGANNAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTG
+
.?C(<7!,"$:@;917"6G#-(:,<?F30D@=A$',)#D2)+1$G&:;A#4F56C,CH?0%%F1H?-?D/<12
@r6805
ATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCCCTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCNCCACAAACATCGGCGTTTCATTCNCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCNTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCNTCTTTGGTCTGCTCAATTTTGACAGCCCACA
+
>>1G)73?@/,-G4FH,F%C3=@"@CG@0B"32+"<#D=G"3E6;4-1B"3C9=7!2G**F=9E2.1BEG4+.&:!8#D8;081$0&2G9"'%E@3.#<&5?+17==G(*-FC78A#9C.".:AC4+$E."$B=(+(&#-#6=.672%/+,$''8E9"4*'972+=<$$/"$=>3(/G'48G':,#*B/;+))?&7,%B7A9$%&F:C/2-4;>7&=@>B=A4-.!52:E+*92FH73.FB>E+4-6:.<4-@#CF?6+9F5D8A;;?12<H3)2@F.$,+6E*#:79+8"7>%G:@$)6+B7-384$D&2@28FC=)G#"56'&6&"3(E<D0("%5-7;
@r6806
CAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCANTATCTGGCCTCGGTGGTGATGGGTAACCTG
+
A=(1AH0,,CDH%/9D@;'C1894=F#$4F3>H,;;#,/0(7$G="'4&?*F.7<(6$?5'<)'D)0&8)-C31A.74">,A>*/#61"90$A2?FF'E+=9D!*1/</?*>?(3$.4)+F8,$2@C&-B
@r6807
CTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGA
+
#0E1#1+8>6:'7?"3/"6EHB7D%D/BC/3C?%=-EFC.C@A,H@!9(&9G+#&FAB'=2)41017H<$6&!
@r6808
GAGCAGACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTNACTTGAACGAATCACCCGTAAATTACGTGNCGGATGGAAACGCC
+
7-=-)*A(C?*<'4+66AG.=)H-HH'*HF0B?C%!5?)7A@3#+@!A38)*<72G("7.H1#&'H)(8G10A91AD&;"CC>-H>2C2C32!")+=9$:137'8-
@r6809
GCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTT
+
CFDF;:C0%@F"-5HD7H7E,DG=H6$"=+$)C0(''.>C?$EG)C@1/C0B2:
@r6810
ATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTNAGATACAACGTAACGGTGGCTGGGTGANGGAAAAAGACATCACCAT
+
?0$7(:!7)6&+H"&-14/.&E/40>,;1+25FC,%&)&*H.D57(>:(D&5>4C@E8$?90E53)@5",32*>C3&!;#584*C-=@C5.CF"8H3)8G0DG:<:8!@)=,72@*4/&A*&--4'%=>!0#5%':&:6"H%7$01<%.<@1=1&37%4#F3GC&G"-<@!.=BA<)D
@r6811
TNCTNCTNNCAANNTNCAGNANTCCGACAACCCTGAACGACCAG
+
%"''%'*"!)&*!''!!&"$)+#'$$*"$"!!*&$)(!+)%('(
@r6812
TAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGG
+
$/D(.1143'$?DH3!$1C&-;E@@/43@&D7D$'5.!,B;(17>1&@C>((-$=;!8>C1E,D+'/CD4;459*8&04FE<EA<
@r6813
TANCAGAAANNCTNGATATTACTGCTACAGGGACCCAAGGACAGGTAAAGAGNTTGGATTAGGCAGAGACAGGCGAATCGCAATC
+
'&!"'*'(("!!&!*(&$#+*!&)')!+&)$!'$"#&+$*&!'**""))#&($!)%$)$''$(*+$*#$)')"!)'$$&#)'*&&
@r6814
TCACCACGNTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCANTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGT
+
%<;?82(B6>/HH08.>A828"=;2#88;+:8-+07C:=.F*E?*3:#+2.H:@-7*&@(9,3AC#,:%?/2='3.3!'*E9D1/0)F62::+69<@BG8E'69#-:C7E5=>E-E-$.?-"/)>'D(+(B:(!(G/9B5C-01%7@D'D4=-%4/'8!B+8-!!@.01:;?:%.(@2C>D5E$)F
@r6815
AAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTC
+
%.$%D'6)3*9::C91,$D;B$"A4E%(8%33&?,B>G'.;3=(C'3?@+E0&6"&G,<;$+(F@?5'!2=C.,?-3%B">,0/:D)'-!<G4%6G>-"@+!/#$?DC9D94
@r6816
GCGAAATNTTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCG
+
+(!+)&!%**'$)+*!!$&%#)#$!%)'%'%+$!'!%%*!*$+&")&(''%(+#%%*+%"'('&!!
@r6817
GGGAGGGATTTGAATCCTCCGGCTNCGAGACGGTGCTGGGTACGGAAGTGAAATATCACACGCCGATCACCCGCACCATTACNTCTGCAAACATCGACCGTNTGCGCTTTACCTTCGGTGTACAGGCACTGGTGG
+
32:3+/%F5,=C7*875#5#8)!/+4+.#=9,'>0&9D,'G@F<!-1$@*2'E8(19(%:F!A=B(96-,7-E:+?8)!,CF*:!,&7"*6<-4A#"7+G(EC/%$/4/43C(9@1E!2-#*:.(580;/),&6A
@r6818
ACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGATGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCNGGTCCCCTGCGTCGCTGTGTC
+
B;4DD;=$/;E=:2B>;;H0)+$(')/>7&1-H67.??7A60F#<%6!6+"#F"7&E>,5;<EG(3%@('&"?(<B3:@/.&!B+D#>>;:9A>'H=GC,;.C+6,G.:$8+@<B9&';3%<)>;)!!,,79@?%C?;4
@r6819
ATGCANTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTNCGAATCGAGAGTGAGTTGCTTAACAAAATCGC
+
'DB(56=&:23-1#/G1):?4H*5B%-"2H=0<<1;14=1(??0+!"H(=&+1'>8A;8/%/3:.B&@A.0,30H6?B&<5#&,&AAG.=0&D-@63=2-77%*>:%3+A3!>H#$'D
@r6820
AATGTNTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAG
+
?G@ED86DG"4.&-7-;*=?.5@%1'>"<>9!1A?BF4>E6,'E'0!@+&+"$);)G1@'#/=<C!7"./C18A!4;.@;9E69"84%?:+-<B4'$</*(/H2.G.8=!#2D88;&--DD4;HF"4#E
@r6821
TTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGAC
+
FDA:7"7*+2=59)4;5$D#.6.G&0:B2*%*#F5%F>!@C#8*E8AD%!+:F"7GE6$)#>E+E7GE5#+4:&6,>"0A1.++G'(%FHGD#A%?)""C&C6B#@DF./90@?<+6"-FH4=518ACD9+67
@r6822
NCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCAT
+
*/!:>DA)G(0196,!-)G,#8*2#0,DG.89>.$5%>%!HB>.;;:)3#3A'B0""??13=@6?<*HEDD*.?1>%/(((H$:@87AE<E8?1AH?/E0=&,%2,,E-9<5E
@r6823
CNTTACCNTNATTGNTTCAAAGGCNAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGNGCTNACGGAGGATAACGCCAGCAGACTGGAGNAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGG
+
$(#*!'&!&!*#*%!++&+")$)!"&"*+'!')%+*'+!'%*"&#"*$*$(%'(&$$""('(*)()%"*#"%$%*)(!%(*(##*($(($##%&'!+*$+'$&&"&'#&(%+"&"#&$$)#("%%*%$#&(#(#!)*!#$%!%()#&&+(!##!
@r6824
CCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGGATGCAGTATTTTCGACAATGCGCTCGGCTT
+
AG)&F6(34,%,3?FF$;4%C2#)()GC)$0&B@A+44,B.%7=(%4*:;-D541C8@8323%:(%1HA!)F)!GH%>H,'>-!4$D'17
@r6825
ATCATTGATTCAGCATCAGAAATAGAANAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCANGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTNCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAAC
+
9"$E"%5)/1%"*)6E=:C:8?089>*1B9CD!-?@'$$()4-:,%6CD2BBA7.F@616E*:3'.AA.?#$8%74"CCG-'A!@?G-"'!@E$F*=*1'DE&##2(G'<3?.?.2B?F'+1;G8/4/BF#,H%&3#)G'%=CG-:"+A=+CEE=<A4.;!-819DH(!;+33E'737090/D/9C*50?&41C1C;;*69")%G@<1&H(@B,E0C,D9--1*#=8?#'=$=9#5,8%$=(=%E1)E:(6E/;.4<,"5!.=D43;!10@%E%=>&>E17?$F$2*<1);F'@/;E@'D;8D27!)221&$;'@?1AH*#D<AHF408<>=:0;)E=H&
@r6826
ACCGCATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCGGTACCGGACAATGAG
+
$&("%%+"")&"!&#"&"%+#"'+&'(+&)%')$"$&+(%'(!%()*#!)#$#*"""#)%+#&*!(!+((!*&$"
@r6827
GATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAG
+
72"@(,(&@*BB:2F:9/3(A4-4-,B(2$=FG&",8"'23(#
@r6828
GGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCG
+
+*+)'*##&'%!#)'#!&(()!%!!(+%(+)'((*&+""%#!&)**#&!!+
@r6829
TGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCNTCCAGC
+
&/&1DE?;1CAE!GE.2H3$:B*CHH=0.'A&G5)%C+*H9'2BB$9'(<.#.8+!B;&EE2):'),
@r6830
GCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCTGCAGAATGCCGTCCAACATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCC
+
6#?5*@!>30EE?'&5?9<780D?0';5-7?'&8/*@.<<6F$&B3F<<,:.!54##F;HD!8F.$6G)/.%'H0+:E6?,D?;.->'.5%#2%4H;>D,!+D1,H?5-"+D-E5%%9,<19E!06
@r6831
ATCTGNCAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCA
+
&%%!*!#)+%"*!+#))%$'&)"('%**#"!*+)'%'!#$#)!+"&*%$"*'$()(%'#'&
@r6832
ACACTGTANGCAACCTTGCATTTAACTATTTTGTGAGGCTTGCATAATGNCATTCAGAATGAGTGAACAACNACGGACCATAAAAATTTATAATCTGTTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATA
+
'%)&#)*!!%*%''%*#)+%*((!&!%%%##'(*&)'""&"*+##+!!!%*(*%*)+$!$)!%#!$)"%&(#(!#+)%&)*)#)!'*#$*(*++"&%*&($")(#())$"$%#!#+$$"'&#!*)#($+!""&%")!""*
@r6833
GNAAANTCTTACGATAACGTAAGGAATTATTACTTTGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCC
+
%!$('"%+$+*!!$)%('($*!(&&!!#*&+"#%&(+"''&*!%#&'(!#!)%%&"$+*%+"#$+#&#*!&$&))
@r6834
TCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGNCCGACGGAAATCCCCGCTTTCT
+
<&9?8?F*668DE;H()7?<;&A(B8-0/D+!-7?,@D3C*(BE36G.1-F'$"%5408D=47A=5D"=>(0.F<=:)>=)A'.?A*'?3#>=6;?'-4A/HBG$G(H73//0G*3E=<4%D@-;9,CE&HAB!?1&'!
@r6835
NTCTTANGTGACGTNTCTCGTCAGGTTGAATGGCATGGTCGC
+
#"$*$*%"(*##%)!(+$!+#*$"%(#++!'&++#*&)!$)%
@r6836
GAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGGCTTGTTCGATTAACTGCCGCAGAAACTCTTCC
+
1%.&:4;F';8HF0$1F1<)$!"''">;;%3?,)!<4D*:(;!:-4!*FDEE(?".('6=5B-7$7$)4-&":(018;,>DG1&,C6:.GH0;/=
@r6837
AAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAAT
+
H8-7.;C#.E>5'"@E9)@F):34&-@=2)"?32*7<1E78*F!("):FD,7'8+=+A3*8?<>%2$74+@."'%F4B":D@//737+!@.'C7";D''6F=+(F-?(<3D,;')!
@r6838
ATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACA
+
G9.$F6(/&FC?04:?&2;82%4)@2!@77"D3"DH*<"H6A3.,+@-C/81":CH./6*/98>4G)#>5'63=8<+/'2B;H>)>5%-#)C-*..%B>%#G/*50$+
@r6839
TTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCNTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTG
+
E5';DDD3$%'%"F612&HG'""C)112.#15+.C-@00"7;!D*H9$#4D@$,69EF>F.5;37G,&$7A#(,2/0:'7=-*521$D8E"$/E7@?A:(;?(!D.**."!7"AH5(2D)2)E#1E=AE2;<;C?@!
@r6840
GGNTGTATGAACAANGNCGTTAGTTTCTCCGGTGGCAGNACGTCAGCATATTTGCNCT
+
&#"$($))'&#!)("(!+())&!+$&!'*($$&#!%)****$+*!))$')$*$"!!(&
@r6841
TAATAAGCGTCCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCG
+
,)(>&"G.4+7)!+ED:BD:37CG<#:(4(.G+).B3@3C>@3H6/1.$(B=%;E9!>..+
@r6842
GCGGCATTTTGTCCGCGCCGGGCTACGCTCACTGTTCAGGCCGGA
+
E&F9/H'.E022"8'$*?-F;C,,5-=-1<0=?);G$0154/+8C
@r6843
NCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAANCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGNTTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGCCGCAGCCCGGATTCAAATGCTNCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCAT
+
#FA03G<02BB)321&C.2A#D*C7&?E>:65$%(:6B.$A6-D9BG1,82.6G=*=.:."@/>E@:@?0#3'B;;77C1<B)+F@2,2-?6#*?)":#+-><.)#9#82G:C7E2"B<>>F6$+9!6(28C8*G,"E:/$$C.)F,+.%/98&9+1"8A@-'&%C86F*!%/"2G6'7(E@HG&;300$.+"$7@5>8$!<!'>%85;,<"837!BH5B<D*F*E0,)769)+%G7<0*48D0/*/5,*:7#<:#?""D3)+:C7D*4;.2G%7F$671H+)+<F"A&H?@B*.;>"1%?=D35%4E'A?D7B/+18,/B6"3.1F2A?30::0A*0/
@r6844
GTNATAANCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATAGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTA
+
(*%#!*'#+&"#)((%$#(%!!!+$#&')&+#)%('%%$*(&#"!'(&%"*!(*%+#%%)%%+#)%*#$"&!)')*)%*&#!*#%***!$(#$+++$!!(+''#(!($$)!#!''"!'&$)#+#&)*$"%!*$)'&)#+"'*%"$*%"&%"+'+#+&(#++*)!&)!$%"&*!"%)%#%'*#&*&)!+$)$'
@r6845
ACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTNACCGGCAGGCAGAACGGGAAGCCACNGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAG
+
=D5,;!1>078F;9"()1=+$C>;$9(B@?8%*H"B'@32".EC6=!.3BG'(@484)%59#C=2!@H/;+)(&!/B=GH'G2:C:GC*043**>5,'-">$"$37;BF<;;//?2D9G#)&>!*+%C356(G25A
@r6846
TCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATT
+
4&#>D5")/3?&FFG#*!@H+2.7.@<@%&$8;3.>B5*%?:GF;;
@r6847
AGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCG
+
,14H.5=99&3:F,!"0<5HG*.$&".<D5G$(80*HFB2&!/+)!1!/;36EE9)1'H9<H">5*;003B7793/0#0/
@r6848
GCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGG
+
A3'$-+7"&</@"2.0+H#CC$B:0@78'C=*4:;+)/CD2&9):AH032&4>9/37B1/@CC=&GHH/4>HDBBA?<6)!'4-.!1)A7
@r6849
GCACCGGGGTGTTGGCATAATGCAATACGTGTAGGNGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTC
+
$:.D8.6D"3?=EH-%AGA>?03F6,6F?7=A0?:-9=;?#04%8(@3&F1;())FGH24+39,"+#!-+07/,4<)$5+'+9?H'7='"0+
@r6850
GGTCGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGG
+
B6;C?(-EB$@,D3(:?<74'8E&8@>C@<';;4!<:.?*9;((
@r6851
TTCCATACTGACTCCAGCGAGAACTGTTCATCCTTACACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGAC
+
G9A;;0G3B8D"')**D*+()H-C@#?1<1*=E',5!=64<6C<7E<C:&5C%G$143/!#A8C*7.4?(5H'D1+#?E4!70<07@
@r6852
AGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTACANTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTCTTGTGTACCTTTTGCTGGGTCAGGTGGTTC
+
*2!>!24;*+$(19C<*7?G%16$/&D-$-*F>2F%?H9=1#A;C2846557()F16@#?G2C6D"<;1BH-(11!:A(F?9-53'G3A>F3E+-"/>9$4FH14*$+F4DH&),ADE(=1;+=FGFA7>&=%H>)F)9<<C+>*;%#&
@r6853
CACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACANGA
+
,,:%#2(?1?#@G"?>*&?&)13C@95F5=+/(A.-)86'85#-5>();*@46C.)?>"0
@r6854
NCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAA
+
#>*:@4)8A&>7')F;4)43@1.9>6?=9*D)6/;/*;8($>'">;B'6%(D)>>'&A=)%4C+G%B@H;6EG'',1!H>9%-:8#6#'!A587#*(<E(6HC*76"F;<C*$C<CD@B3D
@r6855
AGNNNTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCANCTTTNTCTGCCGCCACTCA
+
&'*$++##*#&&"#)"%&&%()$#%"#$""#%)%+%&$'(*#&"#+!#+''%&((")%$"(*+"$('%!)!#("!*#()$(
@r6856
CCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGAT
+
/&+2((=5H@2BD!99@D;%A:"A3%.31$>7A'F"(8.6F66!7=9-44F26+0EH?&9,0D'&3,42!<%BHA<6!)8+E3@4
@r6857
AGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTN
+
C602<?/.+D'43*>'=B8)-615,?=>4*B:F;DF=%..1>,+&.3'#$.C)C=
@r6858
CCTATCGCGGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATAT
+
(>D313-?&EF*3A-C93!G0$',';@C:@:H3++7HH"5)&<E-34>&/F'<
@r6859
ATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCNGATAATCATCACCTGCAGCTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAANCGCTCTAAAGCTTCAGTTGAAAATATTAAGAACAG
+
00&,3(+-G!)F43#%CH:C?&%A7/$,4<-@&0&C3F9DC"&C87B@*8$*9G/;6?B8%3<D:30,!G<B4*'"!*?=&A,773B)+;-,(E:*.#,B25/.D#@9)?A6=2BE,#+!E3'?H=660*+09"3F+B;#5(/"C<.<?&75=:F"*+>A19(%*B>';#47FHB!!*')#&*+09&:(8C5E9<=D>*135!37!A"/56)8&9HCE/-0!8:F?D5
@r6860
TATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGNAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAA
+
+#("#&$*#"#!$%*(&)%!(%'$!#!##*'!$!**))(*%$#)(!($'&+#'*&$%&$'+)(('+!&%!*&&*#'+''$*'"##)#'$&&$%&+&#)&")''""&)!(&$)*%''!)*"%(%'"*)*)")**"&)%!%*()+%%'(*!"&%+*%*)'(&+)''&)#(!&!+($%"#&!)*($&%%&)!*
@r6861
GAAGAGATGCAGGCAGTTTCTGCCGNGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGA
+
C7:".,C<>D./@+(&5:+!015'!@@:"GE9F7G=B2:0C4@!8#%2=212?.,;#=G-C$E22#?8H><;"(
@r6862
GGCCGTACTGGTTGGAAACGATCNGTAATGCGATGAACTGCGCATCG
+
/#;-*E8,A<<4@"22BF18#+G=9->0"/*?H>)8?EC1G52!(!*
@r6863
GNTGCCGCCAAATNAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGT
+
&$2'+3DG?F7$7,D:32=6&=>&1$;.#D/-)0B#@77$@.64.=B)/6"9B$41=4*:G="?1AA0-'6(*)9@&)?1-45"
@r6864
TTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCNACTCCGTTACAAAGCGAGGCTGGGTATTTCCC
+
><B"7F>(>:%D'E756+C7?EA-#%CA6&.,G@8GG&="2#G;C*)%'#F(B*D#!(<-C'E$,>/0=*3":G27CG-)CB.'>*H65G>,.(*?)
@r6865
NAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGAC
+
&G&">HC"?;*)3+5&+B$$$*&F*45H;7BC(%0'3>FHF/;@9A#%/44E#,""&,EH=G0'6,
@r6866
NCCGNCANCGCTCTGGTGGCGACNGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGCGTGAATAAGGAGTCCTGAAAGACGGCACAGGNAAACCGGTACAGAACTG
+
!"$(#&(#*#&&+#"(%&&&#!#('$"#$*!!!$%*!+%#%+"('#)#$!#%**&!#%#$$#)*"+(#)"')$)&!&#'&!&(*"**!#$$)&*%"+%&"'%%!*('*)!%(!&&&%))(%+''$'#*"'!#+%$*)+)+)""!*(&*#'#+'$'"'%)!*+&&+$)(#"*!%'#
@r6867
TTTCGGGAAATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTA
+
,6#'(43*GAA*,+AA8H<784;F-&38!!G0=0G88#9@!$6,F3568#8$"75(%D&@#?7?*#);73FH4F7G(7168-.$-BG.4=-<(29=A*2>9.$
@r6868
GCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCATAGC
+
,;*C$10069/$;?5D(AC>0*??D'*,6E<#/!<7B,)F06$>.+/9*D*#CE>FA2A8;E?$9<:D=$7%6G<A77"!?G*:51;E0*,!&/7'(E(1%B,B7F/!),(+:H%'(',-+.E(*>FDH:0<E2G@HG+H5*:G;
@r6869
AANGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTT
+
$(!3G6./>@78-C-3;@6A2H-52E+"0C+93D>HF2D>1F?6(>?..E"4'>D%(>+A;.$)@(:FA*9(
@r6870
GGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCT
+
GG#F=&.=F2E!$,0;<870)D@893*GG2FE88;%$.H$C55;+!'D#H32'"41&H$BD$:!'9-4G9F,B,:2=B>F,D4%-4>!4B&=@:>C40#H
@r6871
GGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGANACCAGNCCAT
+
'83,<A*<:#!?!%4#D.)2@84G"0*,.0+-=@.3,#A*7A5D-2EE*D'F.7$2/B@!C#,A#)&/+*$12:,)</!6961G3&6*6$A)6$-&'6;-9(3%-%7?*!6,GFD6BFF.2A<0D
@r6872
TATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAA
+
B;5#>/"=,$<'-A2.'D3:'4?/E?#0=30'=>F&G4?;.%*B8,@';6@(78,18<3=87A6!?6H7"B"E/@;</63-<"/7"6,)7?)>$;F5:<"*?)0+24'&1?F;6=8C.!7GH%+>*6=,'@=%&(16,A?'8:"5F-.F2;41*#%.2G=12,GF76'!;:ED3-9$C$?%H+3?B;).>G(0%"$5B>@*/C1;
@r6873
TGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGAAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAA
+
=.)<470(:;F203-3%5<)G">>6=,,+@F;96-8"/F:$:6!*=4$B=:C?1?=,!:7G2@'3;=<;@H#-FDH<&,3@526(E66/>2,69/A0D$@90;;01H."A@&6H:4(3'HG,?(-<.6<+*-6"<555=!GA2*C07&&F87,-15?'9;;B.(.!:2%$-D%<4F.FG@@;D%9#+'1
@r6874
GAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAAT
+
78'(>A<=)&/F-.83-9E%$:@(D<+#1.&'("G/2$/;A?G:'A$6*'&4%$&(
@r6875
CGGCGNCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGG
+
)%)*"$'+*%)'%'!'!#*%%%&#%"&&#"#'#%('%*&!$+$"%$&%#"))++%#)(+'&%$$(
@r6876
NAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGANCCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGANGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAANCCAAGCTTTCCTGACGGAATGTTAATTCACGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCA
+
#6="%>1%6/##;/GE;G!FE=24!/.G(7GF!<799*F/30#4(+?HDHD)<9C$9>:?8@H-B'$1H%2;:5.C8'8*,H/-#2&'G)9$E&@37:$5&.17&;'C((G43%#C%;8.%=#)@?=>'!2.$BH@%)+4??'1@7";@+4F223?("@*A8=+9''A+)GD(4%/C04:FH&#EE:(H'>4$4@1-.2&89"1H#F=B9"19G+GH;72A@F>)9,CE.<2!5F/>-A2*"E,&"+,7C;<F,6A$9)?:9.+-'E40"0+D9=::?=07(-)0:FD03/F,-?HG!342!2'F0"EGG=?5DG*(*'6<)F6%>)G&@<1&E$),E?G*G2/?)-$85=C/
@r6877
CANCGNCTCGCNCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCC
+
$)%)&#"$)**'(&++!$"%$$&)+(&$#!*)#&++#&#$)$%&#$#'&#$$!!++)$#%%#
@r6878
AGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATNTTTATTAATGTATGTCAGGTGCGATGAATCGTCTTTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTTTCCGGGAATAATTAAAACGATGCACACAGGGTT
+
.&7F68:**@A"9*?.0:>E!5>%1.C&88CG1;3@'-79G2A?;2G6@434GF#,C)%*!"/4&,3)<2<<=3H39$;GDG87.<$?(B:,+)8328G-F(==&?!=2#6;2;+6)!G%3H4))95#F>@+6?7#AF(=;6&&(7D+(6F9"3B!(4<,8&;)B;G*D.1(G&A/?,=</+$0,1):+9@3";D2"
@r6879
AGGAGAAATAGGTGTTCTGCTTACCGTTAACCGTTGTCTGTATACGGNGAGTTCTGGCTTTCGGTGCCAGCATCTGCGC
+
*>43:5H!F@18C+#,A+)6CH'-(=CG'9<#5&"<9EFFE-/+01%/D&+;>C/+H=CD4$/E=:E9,/?;<D<;9B'
@r6880
TGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAACCTGGAATACGCCACCTGACT
+
)E3('#E5*#2))&$5*C>#&D-!H503D;>#E@!4820E59#"7>D%.)&E'&<3@'F/EFFH7-*??36((."-11@'
@r6881
GTTCGTGTGAAAACGGGGGNTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAG
+
&=+==A;-#)'*A,"6E%?'F'#&(.&"/'9=B&B?;7.8*B8HD@8EB09:+D,:59)%;,<01+!(4%&//:="A:E-6.*B73$"E=?<*@79-;"()-<A)'?B)E8H;B(,;.0;60BB6;-8"/(1ED.6&?0=@6/B:56>>CH25@--22GD-ECA)E8F!%E(3AF;E9G/@4$:.EB:A50?&%/,'>5+0E@AF'52HH!?5C172=8
@r6882
CGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCG
+
1*G/8<H5-5&B<!<(;#B34'1HA8H?/;DE8(@;31*,(<16G7ED101,:6AF/4'FC(3D$$5615!8@!C)2#"#-*>9$!-<7
@r6883
TAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATC
+
C:D?/GA9!;G1:61C)AB8B$/4#"&?))':E-GHE2'(:/*E3/1#H9A.;#!38C#?7D*D-"-B12
@r6884
TCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAG
+
.(&,*2;F2='9F$13$B?<7@+B+F5"D<D->C3/0@&5"*3(6$/*A:@$(C"+09&);'C8HDA=*5";F$,:H8+B/%F.:%BF'8/&6<&/1!:93<?>C#5)H8-/A%+*E0($9
@r6885
CATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTAATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGTGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCCCCGGTTCAGCAGNCTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACNGTNTACGTNAGCCCGGAAAAGTGCATATCAAGCAGAGCATCATG
+
6A')737@A4&1<#??8B?EF.AB93.)(0+!#A>*A@.(.'.)#$)(?.">=!E(3890@%6*<5<.<,2:%<>H+E!)13@B5EGGF"6?,1C<;)9E$3"%=$A?%"D#$04F,(C,>11&@)H*@=5)A8/1$/)=C*G#.4F!A&$7(&.<4%)!<7%";('G-$+7G8A.,'"*5BG+<=9B-6@+$"'3'/2'<?.:1$=:+4>DF#67&4.ED=!H#,%;@!%G??CA;@2*!77D!"A3%9CEA%D0".:@:>)H9?(<-*$=AC*/'2/4E93H:C*>'27DA8H@"((H3328F!!A*46$3#:'C@46/G8>$F.;!A:&823.0<%*!!G9&"A4<"FD/B9#3<1:&
@r6886
ATCANNNAGCTACCCTCCCGAAGTCGAAATCAAGCTNCCNTCCAAATA
+
#$"&##!*'('"+''$(&*$%!*))*+&%*(&$!$"!*'+&&$##($!
@r6887
GCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATACCTCCAAACCGCAAGAACAGNAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGG
+
G9$0'"!8B)<8$.265)=1'512H(2H)@8"<56:@+@#CA8F3,%>'$AG-E!EE+7(?++"";,3<*$9GC!5=/AA72&A.D#+DGA!4FB-4*%"$A;?F/-8*;.G/7?&'<A,%.9-*A/?A
@r6888
CTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACAC
+
>%'AE*8=//9&,5;@'%,<=&9!,&4!-1>/BB,%5@A*A./3:8/3,$%#E4.:01+>7?C$
@r6889
TACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGG
+
-3)"B97F9DHA#%3/-07+;";5(3#-@&)6@!%,..&F<?#H-:$9G77;5&
@r6890
GCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAA
+
&.>*D.!/<):2:;F;@73(>,.H;62<+BGB#)%)77"G3%?;A=!:;(5"5;*
@r6891
ATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGAC
+
.8+>./4"/"7!;+163.=#1AA2/@<0&'*&$$G#@5'DF?B1.**2)'F8&HB<>H*F&G)
@r6892
GCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGNCGGCAGTGAGCGGCTGGTCAGCACCGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTC
+
,5);E*&A(*!BB!.692DB,7@$10!:D$F3$HFF(+>,#/"91G"63/C"3@")$*+'%&A,-<;)/$>0&29!7:*+>/2=0())9+32-9&>,8AB32>52(':D1,)@'?B-$<*H(?>0#-6",FD!;2'F)0!)0>&A37605".3).@BB*-.*,5--9#5-*&C,G92G:;&/*DH@9GE.8DF$#3!/9,FD)+<6-
@r6893
CAGACATGCTCGTTGAAGCATANGNAAATCAGACAGAAGTAGCACGCAGACTNAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATG
+
1B<G?(&,E:6C.+H(8#=097C8=0&>&((&6854>-/'H*276D187)=?A859D11)E>1;>E=EG54$>8'.#2*9=B44<3A)6C2=DH.,E65@>$5"+G!
@r6894
TGTGAACNTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGCCAGCTCTCACATCGATCCCGGTATGCTGCAGGATAANGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAA
+
?HD,&!A,>'?*G@A"*?>B7=0AB88;G:2!'7.%D;$96:>G)-95C3?B'3BB'A",E)$63:F-+ED'$C9',5'/"B/1;4=HF><);)?*+*>)?G0>=1<+E9&#8)*@9+(4C6674,6!2:)*#;E6$4*;*G4"<679C$D#*"3#4(
@r6895
TATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTAAATTTGATGCCCTTTTTCAGGGCTGGAATGTG
+
$F)?**:&4?4<+H6HGGG+0FD"A='%5@F>:<"5>3>:()07,-<2=C(%1*C;):8F&&##<9@54)AE#!6<7:A>=;E'%:C%?1F!*D23F'G&F?+.
@r6896
TGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGT
+
G0'H<**%B26-B,2:(*$D(!30G$B74-/*6C7,32$)8$%:*@C6"*3E
@r6897
TGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCA
+
$+$#%&%*!$&#(%%"#*&()%!%&$"#!($'*&&))&#"(%&'#"$!&'!"''&$
@r6898
TCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCG
+
H61A3'>/**AD'59+<!!C#$%@B5::G@8#!/B*=&0C),-55@05#C)(A>.H"G2>G47F$;=9%->?A"2FCE+-AEC&:;,#+;*D03<80*:A/H,;
@r6899
AGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCAC
+
*7C-:*5C1G3#*7C$4#("BE)G+HAF06*;3"0;22!)B+1AFD(
@r6900
GTTNCCAATATATTAAATTAGATTTTACATAAAAAACAGACTANATAATACTGTANA
+
#'"*"#+')"!&*%%%"+((!'&'+''!')*&+%&+*%$!'"#%!#")&)*(')$'!
@r6901
TANANGTACCTTTCCGCCATGACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGNCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACNCTTCT
+
**%""++*#+#+'&++'*%!%+)($"#%)&#*+)"''#$+*(*+'!#!&&"$%%%#$$$(!"+(!+"%*$"!*+*!))%*(+#"'))'%$*%!(##*''#"+%"$'*+)""#"'+*))!#""(#*&!#
@r6902
GTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGA
+
H@"9D5>3)-:@:@>'%&59,'-;>)-%&(D0H3.8$DH9>B!GB=*&>G)3%#47
@r6903
ATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCNACTCGCTACTGCGCTGGCCCTGCTTATTACAGNATGTGCTCAACAGACGTTTACTG
+
2G&@A-C2=-G)-':'3E)367-80+:",B!%+,-)C@@-*4D.+;,&.@6C=1;@$$.)B@5A36&E509#:=B9AA:1$9$71<D%;?0/@$EG=GB/EB<+6(G"$F+<5F63BF@4"$"'@?:1+E:>4F;E.H6AG=A6'@<2<2;<.71(
@r6904
NCCCAAANGGCANNGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATG
+
#%$$"&#"&"(&!)+*%#"*(+*")''$*)*"%"(*''$*#&)')+*)(
@r6905
CTACGCAGTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTAT
+
%"1$D?40+(2?8%A;;G!8&0<A"+F4A-0;491'$8@4(@D3"!>/;!>E-,1@0E>>4>4!<4#H4)1<6A>B:#7-$-$"<=F8D:
@r6906
TTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGANATTC
+
:26GBHF230@HD)&9D'F!,,-;3/.D8HG:$H/>CH"D7+(68'(H8&#G);C4<(#B/CG
@r6907
CATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACT
+
0<6-%0B-#.E6?+8&.1HF4B'3#'4/D2C=B)GE!;F>'6:H;(5:G>C<
@r6908
GCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGG
+
.A3?:/AA"HA-/0GFD,#*:/F%@/GH'%4/:-C8'HC%5H26D.#D8FFC*;53;<!;<!#;&%
@r6909
TTCNNNTTNGNTGGCCGTTCATCCAGCAGTTCCAGCACAATCGANGGTGTTACCAATTC
+
)'(##!)&!!%**+#))&*+$%")+%))!!&!&$)#)(#$$%'(+"&%(%($""$)+%)
@r6910
TTTGTATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATA
+
&(&(#'+(*""'!"(!$&+%")+#)$!*&()$'$*'"''+&+%''#
@r6911
TCANGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTT
+
+&9#&,#A=;>#-8'</6!*5609418DAD)=;=G>?*:%@'D8:CHA-6;9AA&;5%0CAH
@r6912
AAANNGNTACTTACGTGTCTGACNTGAAAAAATATATTGCAGAGCTGGAA
+
'$'!#$$"$+!$)+($'%*+(*#+#(+&*%'*+"!%+!($%%!"')+#*$
@r6913
ACATATGGNTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGNTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCT
+
:G0<3?$C5?@F#$-"7H?;&@8;%&26#,!")(5#0D&6&!,9')0CG)/7-;)'E*DB3=45H.=)'C0'&)53=!!;3:*@$#E8?)!.G<C,>B-(&3.&@?:,4;2C(G8<):@>2@4&)2%@5;@,;)EC',/025F(@C-!(')@"G6#0<*"1C77FG8.C"46
@r6914
ACGCATAACCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGA
+
4;4H8/8;;F8;$G8<E24<591>>!<#)A-=B"7$/$G'BE0".<E
@r6915
CTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATG
+
<B6D(<:4&(1=6(EF!CHE/E6#68C/2+F#@B05'$>4
@r6916
TTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCA
+
@HB14!A?G-!#?GF@F-0"<$C.4>E.#B.E=&(40.?73=/F(B&"5:D?G,$;.)93-,B2"4?;6:#6'
@r6917
GCTNTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCA
+
%)##%+"'+''+"!")&%("&&'!!)")%"+##*%(++')'#*
@r6918
GTGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATG
+
#DG#C'?D-B+%?@91!+)99)('2;,;-":85-89):'42#<8>C-%+%><8315?0G2>$C#E/1G*H>0F/<?/'=3=;"?DDC),3;3"!:C&+'+8"$19*).:6A2+&EA<F@$-3-$:)(/@46=D3G<*>)?(
@r6919
NTTTATTCATTTTGTCNCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGAT
+
!7H'5:*EC;)7::F1/E?.*444%FA;8-3@G9(/-,,8;/0=-@.$7;:*6&))@!/0&<!"=4*:&A=,'(#)+3</%4+?A'A8*&.%5?B7E?F3",.?)?1E:*E0=4/68#2@@5(C,#3!G<.BFH/F314<2E(43D*=(C3DC$G+#>B<B/+88!C,<#=0.E=%"66C>0C,A:9.1@7C?"(G4++;#:%>E&?GC2**08/67)"*17&"(7?8?1ED5;/&:8"-@!F
@r6920
TAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGGAGATATTTCTGGATATTGTCATAAAACAATTT
+
C=F3875:,-90)!;8F.?*%;"EE=&+<!!:9F*CC(H.0016"9<,"0;HA#3;E8?!5<7F'0C:!4H?4C1::)FA$&%:
@r6921
CCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACA
+
H0-<#G%(!;A;B(%BH5E(2"5DH9*>%FEBA+>/;<'0C;8$86&C3-EC%9(?/)%0H;&F1@H)/=-".,<@7!<)=,);!:95$#21=%$>440">#<6$-'+@2%8+-E/HC58,FE<"1D4=71B<@B#G=*88>C$-5BF3D9&618!B&?!;::.'#&5%,F>6"8!>A@2$?B"<=D8
@r6922
TATGTCGGTACACCGGGCAGCATGGNAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGNACGAACGGGCAGATAGGTCCGGCTGCTNTGAAGGCGGTGT
+
D4:;&=C,-!'2BE12/1#'(-D1C1B6/'$()/H66':10@5+C1%=F,=)1G6;*=191"3$6F@F=.-HA)'?419G"77)=#.$:/0(6<G;,CD1)=&H$268!;AB1!"(??F>D?'&">FG@D#-"
@r6923
GGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCG
+
,<)!:3&0*H9*7#):@$<5)E:%><?'A$%FH27'!+HH"<4&A:<C3#?,197.1>9$/):D58>9-63AC
@r6924
CGCTTACTGATAGAACCAATCCAGGCTACTGTGTTTNGTAATCANATTTGTTCGTGACCGNTATGCACGG
+
$+!+)!("()!$%'$%%)*#*&(()(#$!*&+&+$(!($"%$")('"&##&)&'*+(%')#"(!**"('!
@r6925
GTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAANCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAG
+
?).9A+<H=>9/'7$&=,.(%H.(887@2%!C>/63)=:-!:9EB)D679/!6"E13<'7(H7G,:-+)%F;33A,:D'G')@.->$
@r6926
TTGCTGGTTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCA
+
>C4&9!#9B%>H7*:$E<$-G#B!"C3@.*:/258>(=5$83';)=57@+"C?H&97(3E&-H6D?8/7
@r6927
GAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAG
+
E0B;"!9(*;02=,24F#9'6H>-;9$,15=,>==$.&>?
@r6928
ACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAG
+
2(-!'5D(H9E$7*/@6.:8:/4*AB9!H)C/2.66F+HH!@<!4$+!5B7/.50HG55==)-1#A81('2)+'4%2%?1;;A;/9%)G
@r6929
TCCCGCGGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCCTAGACAA
+
%)$*($++&**))#(*)#"#&$)+$***%'+"!"!&+*)*)$#$"!!"+$"
@r6930
CCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCANCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATNTCATTACCTATGAA
+
5!7-%-96@269!<(<*G7%)B8+:866(/3&'7(.,?#:'C:A?7%9F'5/-90=C(4:H+EB-DC%,AH)%6<!)D!!)+2D#H''G8<*H@@00&(7FD@6>@9B5?C!&B
@r6931
NCNTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAA
+
"+"+$+#(#"#)$%+'$%&*#"&$'*$!&(#)#%&&*'"%%
@r6932
NTTTGTTAACCTGTTCGATNCTGCCATTGCCCGCGCCGATGAA
+
$*(%*%+)$)+"&+)++#+%%$)+'()!"$(''"+*!'!)#$&
@r6933
NGTCGATTTCAAATTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTNTTTGATGTTTGACAT
+
%+)+("%$'#)+$)$(%%")!+$%&'#!)&($)##*)"&%'+"!*#%#&$%&+&&#(%#!''('$!(
@r6934
CGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCGTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTT
+
#$%%++!%"&*()"#!"!!!*&#"%!!*$"$(&%#$($"+&'&#"!%%"+($$*#*)$+$*)"+!(''*'!%+%&+#*&#%*&)(#)%+#)'#*%"+"'**$!&!&&)
@r6935
NCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTGTCAGGTATTCG
+
&+(%$+%')'*)*#+*)++'(**"*+*&'$+!(%%**(+#*+%)'!!'&"+'*"('+)*(&!(!%%*(&'*"$""''!'""&
@r6936
GCGCATCTGCCTTNACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTAT
+
4'=B$?52)@G3C+<+6G-C<<('-H2(5(A+#DFHB/9'!$@%GE>'##A/5D%??G-)D%>>2?87>@?>0*'BB3B,"568:94.D/:"BD7(85:./*E*)=,;7F*.%C;#?=.<:-&&-#/24@G#"->C
@r6937
CTTNNCNTNTNNGATCCTGNTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTNGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAA
+
*#&#"#&#"$&#("$)(%'+'%!$"*(+&#"#$$"$++%$#''!+'!&)++)(#("**!!$*(+#$"%**(+)$$%*#+(!('"'!*)(%#)$)*(+*$&$!$$()#$'!'$#)
@r6938
CACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCCATGTCGCTCGTAACTAAA
+
D9EC+F@#-*9(=:3)561)D$*7<7GC>>9/=*=B(.D&9--;7.G"=1HG>=5FDCE6
@r6939
AATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAG
+
EG2<=@&%E?=:&('>0>8#G>E4G977-5=E=<%B#@)137F07*%
@r6940
TACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATA
+
!*#+'("#+)!('"(+((*"($%%!"!*$)#%(&($"#")*$(&*''
@r6941
NAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCCCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCA
+
!GD9&*>@3+B$;7*8?865%'$AGCF):10),19%H053!=$09!H74@0,"#>B,C<>2E4C$6B>5(.3F:H=.>E+HE+51#@:G;.,66*:$$C0(.&8'B'$7G-$?46A+;(-82#A;(/%.,33D;&D+%HA,:.4&AF%<D*"E-354<.80?D7/:.+:*3/-3A
@r6942
CGGCNTCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTG
+
"?*?'&"%-B,:A>',!/57:4"6:-*&D508":,GG&!&>4F)
@r6943
TNAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGNTTGCTTTTCT
+
"#+%%%'"+'"#&((('*&(#*+&*))#*#)"&(+(+("(*!#(*+&&(+'+(((")*%!()"%%%$&()")'(&)$(*!)$!%#$$+&(!*!!!#)(&"$*'**"")%##!!++$)#*#)+'#%$%!#"$%%&)*)+%'""'()"'&"'
@r6944
CAGCTNAGTNNAGAACGAGTATCATAGCATTGCTCAAATTGGAATCAGATTTGTGCCAATACCAGTAGTAACAGACGAAGAATTTCATACGTTAGCCGCATC
+
&!%*#''%$""+$!)!*!(&#(()(&+)'"+!"(&%"''"")+$("!#!$)"))*%)*&"'+!))$(#+"'#$")""#$"!&!'+(*+&%""#)$&(""*$)
@r6945
CATTAACGCCTTACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATA
+
G8'1+$@(<A:,,060C<22E$-#6>(;@-G46%0,%H",<E#G>$;C8!%/8E&0D('1)F$%-A6E(!70*BG?EB31(BH'H&D:H),H0#-%8/1#09*CGF*G$E3FF@?4?=B0)/$=!<C*5/8/D371GG.=#"!;;B2A$E@?!H+"2'@909'4AE'<64!#?,--
@r6946
NAAATNGTGGTATGNCTCNNTNCTGATGAACCAAAACATCACAAGGTGCGC
+
"'%#*%%"&*)#*$&&*!%#$#'$)'#()&'+&*$(%#%*+$$*#++&#(+
@r6947
CGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTC
+
%@H3$/2"H:EDH&566#,ACF9;A(:2)F5.$=EB,43A<:D/?.;=G=%39,24,426:FA7"'>'=;)!'$$1*=.!.>E%>2/$1:B.!745G9;#>3-12
@r6948
ACACNNCACGAGTTAANAGACCTAAGTTCTCACCNAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTC
+
'%'*$$(+")'"**+#!$%(#*$%!!!%%*)#%%(')*&+*'("++)&&$'+$&(%'&*$(+)"'+!%'+&(%+"
@r6949
TCAGCTTCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAA
+
B)F'2!22.%A:*3-7#G+,/CD1+0B!B/$B&&?3,1?GDF#725(
@r6950
TCTTTCTCGTAGGTACTCAGTNNGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCNATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAANCGCGCTTTTGAATGTAACGTCACCACGCGGCG
+
+);=.7$67+-*95D$-:6+B67+(2610AAB8CE0AB:1%E*HB6BHA?GE=&D6#-+*"!E3GF:G$H9G.+24=?,H1&)DA+1@F=>8$#6-1F@;@'4:>DCF%!:*H0-"9262"F&#?&2#+E2&(6.G<,!!)F+&@HB.,DG"(%?,>F,G28#BG-0E;A+C5=$
@r6951
ATGCAGCCATACCGAATCCGGCTTTCGATTGCGCCATCCCCATAGCAG
+
@"&888')<?.1##/!'*,E244<B$85FB4($6FH2F,72H2=3"7(
@r6952
TTCGCAGTGGAAAGAGTCTTGACCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTA
+
5@&/)$$F'75FG&':'6G@:E63*"G6/?<G4D<02A$G00;EC6DE1%<&;>-93=4A?&
@r6953
CTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGNATTACCGGTTTGCTACCAGGGAAGAACNGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGANTGCCGCNATGAAACGGGTATTNGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAANCGCAGGCCTTTTTATTTGGGGGCGAGGGAAGTCA
+
:=,E6CD>7&B?!!#60:?G68A%3!@?@0G%!.-G04-05+H)7236?090.@/AD$>9@C-CG,0-C?$=?:@HG<HA93<F3:8,,$F4-#A<"@0'"H$;FCE8)>'=35+(4#.7<HG5/=)!<52G>:(D#<)+=!H&24"C15>.EC>38,2?&*;?4&18-FC:A<C&?/9<#=)#)!'940&$1@)6F32!AC)89A-D8.51.4%-)9E9-G433@6!7*B=8
@r6954
CGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTT
+
3=71F*E=88<D!06C!4DB!88:&C2$5"8=1F*&?)39CCG.A
@r6955
CGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTTACAAATAAACAATCCAATGGGTGACGATGTGATTCCNCCAACATCATTCGACTCTTTATTT
+
?E92=7/:)7+E5A*42E.?G3$85?+0=F&G+70-;F)/BF&7:'A>9CA%@A;1D9'3/@9++AH/<&8,$')>5!8%//"/3&$;%5+01C3F2AG#2D.(6!D!)?"7H(($9A3%6$2,)8
@r6956
GGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCC
+
=3'C9401F?!>:GB%45<;.@,-@(:8!&55=#?(>('E-(AB!F/@73%0*+@7-#5;5C!0?00>@C!6$63A&D')1*>$7(9)C.B0BD1<B@4#?65H476A<>*FD"8<
@r6957
GTCCGGCACTGACTNGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCA
+
F0%<*B"*C?1,-D.*G@2,<1F"5.<:357.?1.6.CD09<,G7%#0+3.<-!5!%0C$D>0:5*!57GH96E7/?09D<""C"0B3E%2>7>EB'D&',$)A
@r6958
TCCTGGCTGATTAAGTNTGTCGATAAGGCGTTTCCATCCGCCACGTAATTTNCGGGTGA
+
+*%%#!(#+*!!%*%''(*(*&(+($"#+(!(*('!*(!('&*#)#(%+$"$*('!#$(
@r6959
AGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATNCCTTTCC
+
#94F1:31+,',???9":+(H;?8<%52)!6+(>+6;0:3DF8EC::&!#-GE23H?9=5HD,*%%!6D131#*C4:FA$':F$=))&G5EC94E1<,"B.6/#%84C<>%3H7-5))G17'$!FHDCF@(5@5&G48G69;5C'D:)"-5<.D,4!.E>HE-4HH#?B&A-!'895-7C%0D(34;(<6C@&C"!0#=18C$!@*F7?=65%?H>#&5%#(%C.0
@r6960
CATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGCAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGANAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAA
+
%(+"*$&')'$(!(#$'&*)'+'*%(+('&")*#""')!(*#*+!(#$)%$+#!!'&%*+)#'!"#"!#!)*!'(&"$!%$"$((*$**""#')''!$$%'(#*!'!%**)&#%*)(+&%'*))"))"'%*)**+*)'!'"+&)$+%')$#*+#"$*+""&!!#(')#&&%)!%%)"*%$!(&"!!&)+&!$+$%+#*!&*&%!!*%(
@r6961
GGNANANACNACGTAACGGTGGCTGGGTGACGNAAAAAGACATCANCATTAAGGGCAAAACCACCTCGNAGTATCTGGCCTCGGT
+
(#%))"!$%!%+!"**")&#&)")#$!)("**&%&&*"%#''*+')%'#)'&#"!!!!)!%$$+"&*)&("&$*(#+)#(+)"((
@r6962
ATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTNGATGCAGATC
+
%H)>-?.H5*E2H</E?"B<+C':4A:7#H81E=51/=+D'"H@E
@r6963
CGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTNATGGTGAGCNTGTTAT
+
&+81F$..$=CB6&&',08(F9D&-)$5BG:C887,910":*-*.5.!A==%=<94)-D!DH:'#$1<+B1$E78
@r6964
ATTNNCTATNGTAGTCAATGCTTTCACNTAAGGAAAATAACATTTCAGGGAGTTGACTGA
+
%"'!"'#'(#'(+&#++%!))#&)!#()%)+(!$$**+"$)!%$#!))#)'&'%$'&$%*
@r6965
CCAGCCANNCAACGACCTTTCTGTGGTGAAACCGGATGCTGTAA
+
&$'(*$''#!+(%&""#*$'$%++&*%$))*#(!%(+*(!$*#'
@r6966
CCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGNCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCNCTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGAT
+
2H&;79+A205="H63!.;?G5E%FEH:54@4#-6!F8)8E;(;-E%:)/8H9C>@&%@-;*+:+,=#(&'-19"#2'H/555%5CG85C?.0*1F4)8?GE:0.5(H=$=8"D1*A4H4:>5,./&D1G</.C'DD4E+.,5,)%:5*FEF809',DF/$<89/BH@-0+0-G?E/3F,2G9%H$8")@,+24)$:%F)FGE%&%$62;>!)<'D<E>>),1()14C%+*65*.(66#*F?@4>A,-,-H<4%.>"
@r6967
NCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTA
+
'.>?30'3-&/#*):*48#D!D5GF)05DH%0<G52*<!4&78A9-)
@r6968
TGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTG
+
C&73AHG'35B').9#H:-=BB";<#;9?27*-F8=*.(#)D"8
@r6969
TAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCANGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATT
+
."5&0,$@9,%%GH-!@C)+:1!:<GH(,$?G?A+H$C@=#;9)&86?=D#&#@8CD=FFB>;>@):=+,:?4:$F.1D5!B.;.&E2@6E-G#12**&8B*')E#9:"./,/=(#51CF!F982C+B'F%)*-%"8>#?4*3!(@0-C)6?$DB53/
@r6970
CGAAACTGCCTGTTGTTTTCGTCCCGTAATNAAACGACGATGTGGTTTTCGTCCCCAAATCCGTAGCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCATGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTC
+
(@6@)7%$$;/#''11+*F?H07-<'.FG"0<@<H$D$=*.;8;4'2C1+D'F<G6EFC>-FG8!79%:D(FC3>5C+H'+@5/=6:'F>#85&!'G/7$/8+?,:=-0<&:<78&/!64#&!%A((&F;%"&<@(#FH;A%G):-B>)&?#@H=2>/C@D(5(5
@r6971
ACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAAT
+
G*%)>B9DG@F/?6<A=2=2+37;4%D#/AD&8;BC?-=:,7HH;;)#4C#="/7;/,@!12"&-<",0**EH<9$E6-:G$>:+"2*GD&";+.*?F6H'A$EC&!C3;DCE*3G%>4AB=25
@r6972
ACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCCGGTA
+
#+*')"**&!(""#""&&&&+$+((*&!&*)#&*"(!!!#+)&!%$)
@r6973
GGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTCCATAAAGCTTTTCT
+
E,1H$+4268B!00'1F""+"E99'=F9A)+;<1@>5@00&6.28C&:9=C!(-?=$$8+9>/$/-%(".-H8?4/)*@"8%'5!;1*=5"0&
@r6974
TTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTA
+
/6$B@9A*AGH&3E!BA!D8&H</(=(D'8(A7/2=4=A.3%";(7*@/,;'"49<F/A**3>2"E,G+(A$E?5"&@55920;'E=C!>
@r6975
CTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGC
+
17?E?.5629:E208C31'?E%(A=72A%+,=:A&ACA*.-$DC2#G!$3,(B..!:D6?F@<"?()C?/:'H4E6:("@54*(4F#=#D9
@r6976
CGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGAT
+
>=)@G>7F!2(8:7H#-/,)"07%,?:;#<,//3'2F6,4#27777%:H,!86'%8<19CA.&0(8D2$-/)=".F49H7'.;"7*"51G"3@*
@r6977
AGACACNCAACACNATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCANGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGANGTTTTTCCTCTGTCATTACTTNATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCNCACTGGAGGGCAAAGNACATTTCCAATAATCAGAACAAGTCGGCTCCNGTTTAGTTACGAGCGACATTGGTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAANGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAANCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTNCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTG
+
#'*("*++!)()!)$!&!(")%("&+"'"!&$')'&!*'('*%+)')#*+*%*$"'*$'(%*''&%!(+!"!#)#$*'!%$)(#*&)()##&(!(!&+&!)*))!'%%*$(!!"#(*)%#&(#(%&!()$"*(%+'&!!!#()+!(!+++##$+")$%"+&""$*($%"++!%$+#*)$%!%%&#$#'++'))*%'+%#*%!$*'$!%&%++'*(!#+%"&#$!*++)#+#*#&+(&%($#'%&&&$)"!')"#*!"%'+$#)#"**+&++$#!(&%"#'((!!($!$$*+'%&)$"(%+%%#!+%')'!&#'%(*$!!")(*("&#"($'"++'##&)'#"*+#&'&(*!(&(!!($!)+(*!+*&$"(&*(*!$!&"$#'!"!*$%)&$!+(((+)#!"&&+#"&'*+&!"')('!)&%'"*(%')*'#'('#%""#)(*!)!*&*+*$$&)%"()("(+!""(()()!%*"$%(''&$'&'((#'&+*(%&!&("(+'("'(!##"#'%"++"+%%$)!()+&%*&*&)**((('!$'!$"*("*'$'#&$'+*#)""(
@r6978
TTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGC
+
7/'%<8FC1@#.FF1#26?@4-11++=1!>+)'!?%!8F*7F9
@r6979
TAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTNTA
+
,&6*G/77.;+0)(',4*$68D=/)$$#$E%+38D?*C".9'?14HG;=;)C1A3115:G<16C/>.,!.8#**9C#,<!@-);"%0:?'?+&&6B1*,E>23.?,"$AGD'!*.46@;3?)/'-/0(H1<B
@r6980
CTNATGTATGGGAATTGTTTTGANGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCANTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTG
+
"*$<)C?#@F*0"D)#0>,F"2<G(1H-4A8B#.<+4C697B8DGC)///#?%?"8/*D7+B7=*&'H1"1=!5CH9.9,0D>E(3)%9,$&=>4=6%%,%#<):;+09!<C3CG@.27>BC3!285'-5")!<:!C6B/))*H?$B"0-H*A-H2"'%-4:429/"0'<<<B0=-/);34:C/A+*)A*0+,3FH'H$
@r6981
TGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGTGGCTGNAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGA
+
%+;,#'G:7!E7:/;D#3:%!$(AFD4";,3;237@@21H@10HH/:>#:(081D:-G/4118H4,=#8!!*G)&7F$FG*"'=?A!3#C=?73=5*@<0!B28E8>($
@r6982
TTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGNC
+
1F=30$C;+AA5.B;2B$5//.C.%D36;819D5F(=9>4205+;7:808'E@$2)+!A(%#18
@r6983
GCCGTAAGCTGGTTGCTTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGT
+
:?(/@+B4,.%?&,$:=74B'5A9&*$1-+D=,0/=9B-;C*A&=(1+(6#H;:C0;>3#(FG.=%:>)-6<9F*E2$@8B$+C-HC*$-#.E
@r6984
GAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATGTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAANTCGGTTTTTTTTCTTCGTTTTCTCTAA
+
':'D($B"9-)9+/6/,*-*(F<:4-$(>!"06/(!G:>A)B%4A*E5C79C3,1C%C:.4$;#6H1#9FC3)6<;52-(*,EH4/198'A>!48!+6*,"7;DC4>=.,&,>#9>G/-%B-0-/H?H"#;&%-EA/6??0=C/.H-#!"C&'60A"?"?090A,270H&*>;=C,HB.22A&=.,/>:F',0BB'E;D*>G,G*.'-D)G#:-*1*42H?EB</BA
@r6985
GNCTTGCAATGGAACTGTCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGANATGAAGTGGTCTGATATCGTAGATGGCTATCTTTATGTCGAGCAAAGCAAAAGAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATNAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGANAAACCATAATTGCATCTACTCGTCGCGAACCGCTTNCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGG
+
$'*+''("$##!+!)$"#!"$%)$&"$#&++'#$+&&$&*")++'!%%!*$!)#'&"&)"(("$$!($+($$'*(+*"#$#!!"+'$"+#&$"#%*'*((%*))"&%#'$(!$(&$")(*&(%)+&%$%(%"$*)$"%)$+'+)#%%$'#("!(((&'!'$!)&$$&)$&)%$*!%(+&&&!*!(!+(!!*""'"!)#"%(#("!'%'"!+$))#"&)$")#%"%*"$**&''+'&)&"&(")'")'**'!"!#!'"')+"(#)#*#"#&(&!'&%"$&&&!*)&''!*)+((#')'$$)"*!*+""+
@r6986
GAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACA
+
'F"1?,"+>@%/3)/)"E/&></*4A2*2)5-.=H1<)E#D4);6-H6($#CG!%0%",2:'+!;D'A*B"/@)?%#=9B-"/F>78-0-B1)E,320>,)G,1,D8
@r6987
AGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTNCCCCGGCAGACCAGCCACCACGGCAAATCACNCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGG
+
*'=H+;7E$2@-8/5"%C?2"65+'+$903;#0A*?<8'00'FFE#B/">)-(4")"F$;"G868#G6D/B@!*"#(8;E9/<D2@30&B@H/386F7@??>;.A"6H1)>*8BC;H
@r6988
NGTTCTCAGTAAAAACCATTCCNGACATGCTCGTTGAAGCATACGGAAATCAGA
+
!-")8$@*@668/EG)&B+1?)G=C;1:?.G2+:6-5AH.<;!><"&>9$>39=
@r6989
ACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCAT
+
H0"D<8#;=C@H1='FB!<>8HA;,GF'F4,<<0/E351*/+B;)E47;BC!6@&44#G'.-H:8H'!5'67A(D,)
@r6990
GATAAANCGCTNTAAAGCTTCAGTTGAAGATATTAAGAACGGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGNTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGCAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCA
+
D5>$+7%D2AA%1/!(#F9#=4&.;>"F19$!352%!.6F+"4&''B0.CD,44H0?562=.?%%,%H4FEDAE<:+A)#9E(6=**+=-'BF:7#EBF,>:'C%$3GE-"<E&0&=A/4:325/G4G6-49H=/E,0.(,@;$.CH#$!=9=;*1#2>0@37,>5661;=G9$1#B,+EE<21>>*1')%?H88(/4
@r6991
GAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCAC
+
G1$DHFH=%==/*%#4H.!&E-*"')A-'$8%D9;B?4E6=HC&771>F/&64%$,
@r6992
GGGANGAANGATGNTCNTTTTTACGACGCCTGCGGCGCGAAAGGNCAACCCGCGCATTACCCAGCNTGATTACGGGCAAATCCCCNCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGG
+
%%('!&&'))"*%#*&"#'*")+#*#)(&#$(*$$"'""$(+#)$%'#(")$$#*!*&"!%+%"!&$$$&''"&'(+$##+*$!+&&"&'+)&"#&!'##*("$$+#"'*#(#"!$+$&&)$!$&!!$+(!+(%'!#)%&"+'*!"&$!&"$"%!+''%%")(*
@r6993
ACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAGTACAGCGCTGTACCAAG
+
6G-G'#+<&B2D3B>1&6+";"8)9E0$)9D)8?1EB13ADAH-"@1<%!,D=@D:+'%7C"%(2=C(E3:=:G3'C27<
@r6994
TCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTG
+
>A:(&6):GD$*G&C&E0#E-.:D*H5464!H5-'98)+*%'&D>34<+C33<>A8/3=(,,?4H=,4);6'A%@8!D4"*58E"251"G!+:#H17.HE&?3<0@G)02(B64,>+D0H4'$+,?/9C07:'G+=*:=(C7>6;98*CF1(3,&DC+/'>)#&:H=!&D0DD'&)CAB#F.<-GB$A!"=*G'8=,<?+)A3$""<1=)
@r6995
GGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACATCTCTCGTTTGCTCAGTTGTTCAGGAANATGGTGCAGCAGCTCGCCGTCGCCGCA
+
,B@4E8F1$1.,<,@5+B%BF#0#%"A>?5>B=.14#%".888.%%EA..@F;*"G)3!GE)B#G3")*&2(#@$6A*$+4#.,'6%H+A9
@r6996
GNCAAAATCCGGTAGTAACTTGCTACCCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAAT
+
!"+#)%'!"+%((#&&%)'$%$('%""!"+)'!%+)*++#!)')%*%)")!)(+")!)%##&*)&)$##$(&#!&'()*"*!
@r6997
CTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAATCCATCGGAAAACTCCTGC
+
@'/G67)+7@(&/803F=)BD#,>02A*<D<84'C5)+,('E@959,>6H/5:F79AF$;AE3-AH<:/A3')D)276*1CA:$*F
@r6998
TTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCNTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATNACGCCGAGCCGTAATTTGTGCCACGAATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGC
+
?G60#$1+$!5EEE-;<$36+!?=#6"'1E,6(%.H7%E<#"7D:<3,;:!GC=#GD@F$4D=#40C))8C3?$1--1CF18$$>(G%=.--5-==158;+*!6FH;=:@??</)#!18:3+9%8B(;ED>!6,31DBF1%)2;$67<07;AE8$6@-449%!(F%961(;DA3/2*E#!"D$8<&D@DBC,.!5(C.B<86!!7-27-+#=%;-10?0<B!1:,HA1D82;>84C.0/F5<)&;-7H
@r6999
CATTTCACCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACNCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCNGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACC
+
$E=F'7DBC5%7@((3*,2;@-;"3B;5$@=!4<;<0)B43='7)/5H"$:'(.2"3D'D';H85$/55.8$DD?F9+,'($+@3-5/'A)"0>=#A64<%=%2.;?':9;,!<*,+C@HC>'D-1#H*?34,AE>5(1A+"-:!,2ABE7H(4/D,0.C<EBD(#?HH99@6H"#!2GE@
@r7000
TTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTT
+
D.,B&=A>D8C4%&7(:54>"2>*828%@E&C:2=8*B"2"?6(#)69"+.5+D0=-@=+4=$GH!#?FC*,2+%!6=9E!;E3A<A3.;H::4;D
@r7001
CCCNTCATNTCTNCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAA
+
$*%#F8&&:4;0>%782E<1,<-C-:H40"@!5=?@6C(<5%&FF!).)=&C%-$0D",>H53;<#H*:F!6@%G"!$:H,#'8.$*'"1@F*7/1->17=5
@r7002
TAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTAACGNAACC
+
E@5@2>+#3ABGC*H1B$4$??D#?336C/@:0&G@27E3(*A;>E(@:/G+,.;3H?=6=:&9@0A37)-,/$&(+-,>EHH%G!AB9?/!+79@(,G%-
@r7003
CATTAACCGCGTTGCTTNATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGC
+
72CE+0?*%@C%4'003;1590=/.3#;1=F)<#C+#'B+.!*$@%,+,6?97=DE35.H(G&81AB7$HE$.97,@8G;"DE"(B$H*9(8,!F0A47BF4EG)7*#0886EFD=EG@@93G>7FA9+93=HF'5,3#2,%@).E-!4+>8'%C=@46=#AA@==.4>&&,+C4&B,4A9/7<3C*!@.B3>>3BG=)(5934A+(E*D>C/>*EH"%8-5C2%76'3!8,>H;7=5&/,9;-+F)*99@?B?
@r7004
CACGGTATNAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTANGCCGACTCTATA
+
;C=-;3&=3:7,;&*5),<!+,;6$;G"B#=73E5/1/.H*,(H=F"*A.E"F'+8<3:BF,-)12-%-D5&#@#+-87=;/A1:BC1:)96",
@r7005
AGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGCGCTTTCTTAGGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTGAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTNCAGCGAGAACTTANAGCGAAATGCTTAATAAATGC
+
.%DA<7B#$@:*@A=?85D<)#9(55;=*,ABG'"CC6>5.A<1%*%))83AD-,"?:,D=B/3/%;%="(0D365-",4-"&?(C9!,2#,.;-+2BE>E"6:=DB78!.D@>H*=.@/!2;5F/(11B%$.@>=&F;H83%68*1+/;7=0+B#)9?+D4<$CE2*4&3&-@?;:);#*H@3:0,B>'0>H#$,+,6*5)9;HCFC>H@2)1ED?8,6$?,/>>$.BB*"9<!/!<2)'#G
@r7006
TGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTG
+
-B%(5@;;H.22,E/@>4@1ACGE!>*%D(>"AD"*/2*F=>!F!@9
@r7007
CGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCG
+
?34/33"@9%@9<;14-)A%@439@*HCF:*3$9'B@/$/74!-GGD$#@
@r7008
CGGTCAATCAGCCAGCNTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCA
+
HD)7/@@D+9&&?)?"+A#$*A+!:6@F@.H,/8B2/ED?@!'.:+(0&G'#(@HDH!2./=49"%!F#;.=61@!"<<*A,C26"@>
@r7009
ATNAGGCGGCGCAACGTCGCCAGCTGTCTGCNCAGGAGAAA
+
%#)0*G6E&"=G1=1HD=B:?4D?;C55?H-<(H",/+(B:
@r7010
AATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCGCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACANGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGC
+
7"82:;/&:>6,9(ADH<750-!+!'.$B<E'("8'738H*C7.)),2&54B!.0>!F5!=G(>$(3F82!8"7H=@%496%9,E-B>5//)A8@),97=!D%7H:9C"3B=<'H9A<H65'.43@-!>F035%;B#(%7>,/2=#++@5<AA)93$#)#(80)FA<B4!$B6A(><,$:%<BE"-?H>H.@;"B;.>!F225.%,%3++GBD*(E)&+.+'7!D@G,,-6/F:(B92:.E!0EH0B/G-#5!%
@r7011
CTTCATATTTAGAAATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGNTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTAAGTCCAATATA
+
F,--3':0A?3$:=("H$14F1H0E:%E."03/.,C36=)'>>GA%7#D<>.4<*'A>5(@)?5?+3%C!*5>!/0?.,(B77/90>8)8$G7EG48!B@1"6(&$C+$>(G$@%&E+1&.";>8?3'5!0*C@"B@$(A'.%#7@/6@*##<8/+*3!>2/83D#D8EB5F67!5+$?8*+,B*$H.G+->.E
@r7012
ATCCGTACCGATTTCGNTAAGGTAAANCCCGTTTTTGTTTCNCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATC
+
2H>;50A>$,/;A=8;H;41.>'%)$.,?.E;-6(+#5&!'(>:E$9;@C(#/A59@ED&#0%CF46/25,G0>+&7*1643&=)&GH//+/"A;&BG-E
@r7013
CCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGA
+
)8.'($)G@H=#:*392.+>E-%A-7G10H3>@/2-<*D+==5%(,<59CFG.'-$?
@r7014
CNCNGNACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAA
+
'"*"#!+()$)!&+#))*$#'#%$##'#%(#*!*##%$+&'*%#))#&+'#'%)%
@r7015
GATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAA
+
5@"G,?::0%"A2(H3:E?8.($>=:@<,),2*5:?/*)+;B368F@!C=-#*7=67#@3.A5584+"9'G*,
@r7016
CCCGGACCACACGATGGTGGTGGGGAACACTCAGGCACGCGGTCTGCACACCTATGGCTGCATTCAGNATGCGGACGCACCGCGCGAAGGCATTAACGCCTTACAAATANACAATCCAATGGGTGACNATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGC
+
!:):6F;>EA"+'H(;:%=B//90%E;/$<=A3DD1HDH"C45GG47,#B,8E:EE4*!5#8:D/<!'4C/>&08!6!H-?-";76#*95243:H89"F4E97:@4$$B2:%D--&;C("6:&#$*D?=.!:%-*7%632F+915*C3%5421G6??'F!9G.F.4<0C?<
@r7017
NTCATTGCCGTCGTTCGTATTGCCCATTTATCGANATATTTCCCATCTTNCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCAT
+
$B<&&FC;0FG/HH5G.$!$B8B>3F7(8.GA>!B#'&&1%-.7@0+0;AE9C8-:.-25G16.//"0D/,<0.!C!2DF0E5*91/;:=;-HA:?2:&@/,FAH20<?#G>86;1-:BBC8A-66HB5G.)#E<.D?07?G$H%75C)%DD"7G#C>G2#
@r7018
AAAGTGCAATGCGGAANACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGNCGTACTGACGGATTCATCGTTGG
+
/57<+A8>>0;;8:9HD/:%7?.'4'F-GH>6&,!$G@$%16(-:2?,@E9#2A>;'<4,%'=2EB8>,8!+8--3AG9;EH1==92"4+,F+(.=52E*1*3F,.@/36-6.EH"//%H-.F6?4+.#$/F885-?6;-,
@r7019
GGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGG
+
9EEH<=!0+93@A:C3>1*9'7F;5??8,-=2D0;1?$:-"+A9BA/E$-A?@*8)?@A1!&)3G>7"G$$*+9D@'?)
@r7020
NATTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTAC
+
"3%A5,%$B*9+.&1(F:97&4#@FH$E184/6G6@>@%AC87!
@r7021
AATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTNACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATA
+
1@,*$/A0-!0=<((%AH/C7+74H:/31!9&G&ED+;:1+7H4=HF-).=G77'!,A(*(*<"-=2C&%F:!@=!7@>/+&839*+'73-!2$G2(<*64F>2=.B%*AG#=H%'C%#;C#/=)BH%01#&8/B0FG
@r7022
CGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATAC
+
;6+6=,(/4B%3(#!D9+21!>-C=%3F3(6+B9+$''?G=*'>+
@r7023
GACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCNGTTTACCCTGTCATCAGGTCATGCAGTGCCGCTCGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGANAAGGCACGGGCGTAAT
+
"%D0"G%'-:5(#1'>&/-6)D=="?H"D:#48.D)9(4>+:7%(9)@%)DA(&7+)H%.2)6&+#D"6GC<F*ED<9F!!D$.6?*1)#$=,G%80H@>/@F#-:"(!#:>4H?!/0A(3<(>C.7H)37C99>$%CC(C%,?CDE5".)02;
@r7024
CGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACT
+
8/30#&G/B2?H@>=3,2#;ED"FG21HDB1<C64(>(@E=.56>H+0")#&-&%**@@:==$<.-55+-"/H)>;1.A>B&H6;/<>=;2H*E#8/..-%<-)-@3*CE(+,HGDE=-AG=C-?76F&F7152AGD,;!5(!F"H(+/%!!A79&9(B*-A
@r7025
TTTCCCGTTCATCCAGCANTTCCAGCACAATCGATGGTGTTANCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCNTCACGCAGTGCCTGAGAGTTAA
+
&B&.#8/1)*/,B@<BD&C$*G!&-9711B9'8H%+)=&<)$2-(='D5*<&)@8+E#+@17(7#-*:=7:C#F5BD7?E!G*BE-DF.="E./2#?+&4?A,2#%%02@)"HD3/A2=%@)2<@-
@r7026
TGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCA
+
H9;+$$BBC>*@7/*.%F1,504G$34.;*;FH>"&63/@>H.(/<
@r7027
AACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGC
+
'@<##?C.&;+0:5H;C@/2:"$%:8:)@!#A,A;$!G%AD&=A4/897<?*.%C47;3)A%C;/958C%.
@r7028
NGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTANCATGATGATTCGGGAAGGTGTGGCCATGCACGC
+
!9+,:"A-BCG?0#>D9@$#>=+8/$B/)7+E5<9#*6@&1A-<+CB14;<,G@!:1(&.2%"H;B-&<G.G5/"B;##=3=6".;#@@C7&*$6D=D:!,=1,79*%
@r7029
ACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCATCGCACATGGTACAG
+
G!H$AD5.<3:';?$&>993F$F=>H@@H5A)3%%+/!=+7?=-:3(G7@&.HE<?5
@r7030
AAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATA
+
EE4+';D"12#"+FDF1HE3F%#;97*AF>F83;!?:'=)90
@r7031
GGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCANCTCGCTGGCGGTG
+
+<"6'&5'G;@#3EHB9G>168625D%)%9,A6>?'G>+86&F1)D='>G>3;"F
@r7032
CCANACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAG
+
)#&"+!%))&%*+""!'*"+*&%(&$+*%'+*+)%&#"%#")#"+#"**!"'$#*'&!+"%&$%%'&($#!'(!&
@r7033
GAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCG
+
9".19.<9+"E-B83=+#81*):#1B?G:)#3'#A,<BG4G99'D-F?37&;=A<E3F228/G'2+840G#5B
@r7034
AGCACTGCGCCGGTATCGATATCCATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCANAGATGAACGTGTCAGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAA
+
&!"+!**""!($++*)$!##*(+*#++%+&!"%"&*)&'"*(#'*+**+!+!&(!'%#%%)&#&&%"##%*(!)*')*#$(#$!&(!#$'#)&*+"'*%%(&!$(&(*)*(#+)%()+&)&+)$#(*##**"*!%!((+))+*"+#&!%"&)!$($*"+)$")%$&'$#$*)&%+*(&+$)+%&#$!#("'
@r7035
AGANTTATGGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGANAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACNNGCTAACCAATTCCTAGCCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCNGCTNCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGNTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGT
+
&(*#**$*++$!$"())"&!$$+#$')!'#**!")"%)#(+!&+)"%!%)%)#!'&**('("%&#+$(+*')+#(%"%(*&"$(#""*)%!(*)&(&++")!+%#*%+$$(&)"(+""))'$+(+")+)$'!$'#"#$*#!&#"*()'*+)$$)"*&''(%")&!$))$+)$''++!%!%'&!*)($!!!#%&)!!!+*(('(&"+(+$+)#)))")$'$&%*+#%$%#((&#(''&))##")&*&'!")#*)'%')!)+)%+%&)'++)+*''"$#!+'*&"(&)#%&%!#($*'"%+&!$!))"'"$%*&*$!'+%"+!##&*++#$)&$*!)$&$%%%')")!"!("&&#%$$#%!#('(")%$)'")+$)"&*#
@r7036
TCAAGGATGCCAGNAAGCGCAGCATATCGCGCTGTGACGATGCTTATCCCAAACCTTACCCA
+
?$HE<F4HE3#<D.>GE+4?5F;(;.F3F<<2B1;CGH$(::-)5;@2D552<73<D250.#
@r7037
ACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTAT
+
.%G2H,*%=2&@$*,4-'?59!4'*"B;0C4B6'88*)-'@,,#D8&<5;A687>D;@
@r7038
GACAGCGGCACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACAT
+
&&('+#'%(*'#$')*+$'%!(!!)*$&$$&$#(!")#%!(%!*()!$!!'%*&&)&+"&%('!(&)($&##&$"$
@r7039
GATTCGGTATGGCTNCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGC
+
2G)F'-6(')@.%5,@&!/#>F1')H6-3B!>D4.E"+D#B;8(#4D,&D2$A.%9#=9C)?$<#FC,C7#@H.9%E/*D4A'9):87!#$=,GB,*=:5==:6CF:2%H##B60,&E
@r7040
ACTGCCCGGGTGATGGCAGCAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCNGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGAC
+
AD1,,5#C8D4+6D8/!-324+6H:.-@.D.28E-6D9>DA.:A!)<<8()C-A=*"7+;-8>;&4#6%:D?6,!#*F@'%!)*B!C!5%2..,G&4$A!AF-(=12B(964""?.,
@r7041
ATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCC
+
G8B491#80B=,F+DF!5$&<A?2,;7,:&1'>-$D"7;2AC@)4!9B$@.!@#<>)+>
@r7042
NNGTTGCTTTGNGCANCCATCNTNANCCATATCAACCAGCTCGCTGACG
+
!!!(*$)*'("(***!#!&&'&'$(")#++*)"%(!$)+%'$(*!)()'
@r7043
NANNGCCGNCAGAGGTAAACTAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGCTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTNACACAAGAGCAGCTTGAGCACG
+
$&(#$&'&#(+*!#&+*(*#"*$+$)!&#)))))$&))!#)##!)*#")%('!!#&$+##)+##$&!*&$$(#)')&'"(%"&*$!#%)%&"#$#&!+*"!*"&#%&++"$+'&%''+!"
@r7044
CTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAG
+
5:E!E:/-%;@/"!C'7<<<+7E="9?=9&7'672-48!7+4G:;6=/
@r7045
CTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGT
+
9==04E.%F!;??9!=1"-)D38F/%%F<1,G>;#C$<:&*#(2',5EC?'5*7'0+F0""HA%!;1;&;C+D*A41H@#A%B(<
@r7046
TGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATT
+
/!?E-<8<<9$FF)7,/C;;;>5A9A5:;G"FCC99(:25G,1,?$"(4FD;+55%6.E$(B?.7=).<*H-#@>
@r7047
GCTGTCNGNNTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGNAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAA
+
''('"&&*!"+!#&&&*&#"&#!#(*(%%&'$%&&))*"*%!$)%(#"'')%%$)(!*#"$!$'#!"+"#$(#%#$(#!#'")#(%)#)#!#'&++)$%+&+)%)+*%*"('
@r7048
AGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAG
+
5,@28?@67>7,>6B6*)(=99<7:2.BE3.!>?9)G(CA.=@C=@;0'=&3F3
@r7049
ACCTGGGCGGCNGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCCCCACGGACAGTATGTCGCAGGTAAAAAGTG
+
@*F7D&!9FH-<;E19E,$!+.(8/'/%$D9A5*C");8.H*&8A2;@!0?>6GA,""';-?)5E'@"-*!$(FDCB:A12/F/"AA<D/E:.,F,.1@?3=:3/'+/D
@r7050
AATGGGNATCCCCATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTNGTCATTTGTTTTGGTAAAGAGAAAAG
+
10$#.%4$;@$GD:?$$?@.'%)&/-9&,%*F?C2238G45!C?4'#H)7>8D'(>)!HF;5(H<<4+@/&3H!E1F>;4E?#38,1?DB/C&#E7AA.*(7>'+,+<6*3<<3/BDG
@r7051
AACNANNNCNCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAANTGTTGTTAAAACAGAAACCCAGCA
+
*)##)%$!)+&+"")((%')&(()$%*''"$"+$#)*!'*"((##)$((('"'+&&"$&"*)+&#"*&&!!"%$")!$!#"&'*(!*&+&'&!%%)!%**%$"'$!%#
@r7052
TATCCCACNNAATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGA
+
")'')(%)""!+!(&)"*(#&&)+#)!))*&+"&*$*("**+&!(+(('$$)&&(!*!#'
@r7053
TCGCGCTTGAGGATGCAGNCACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGC
+
H475B3G0/AG/2&B7:(?+7;7#!."9:/2HDB"BDD%@C864*27:H21-1*4B3:G#8.<#E42>4:7+E49G'250:.
@r7054
NAATATGNACGNNAGGGGTTATTTATGCTGTNGTTTTTTTGTCACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGATCGCGCTTT
+
(*")#*&%'"("!%+)*$+%&+"#%!&)$)"&***)(#%($"!$((!#*#%+$"+"+*#+#&))'"'()''*%*''))%&&+%!%!$("#'!!&#+!%+*%)#!"$)"#$$($$)*$$*#$!!$*%"*%)#$+$"+**"*!
@r7055
TGACTCCGCCTGTTCTGCNTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGAC
+
:E5;=>$36BE#*"/5+AC1"3BB+,A.%&F-64+,#9*F.@7(-0;:@!;+%/@>-E#*,&#0
@r7056
CCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTG
+
C$H95</A7=.&="C'GD"69CB+,/A1FH:.1<23::+!9'"C62=#5F:(=25>'.-)H!,A<)G@6GE&!>@;8F69>BCD<*F;()!/H"E">F*'.6A297H5(%C2A74)6#1".B
@r7057
GCAAAGAGATTCTTGGCGGAGAAACCATAATNGCATCTACTCGTCGCGAACCGCGTTCATCCGGCACAGTATCAAGGTATTTTATGCG
+
96(4"1.+--14E/$B-7<$E?2?E>;$H/;-B(>(()3%H/2773)2)@(2<7(<+.A#*!#,>"!9&5&1*6.1#E3?>?GB&*9,
@r7058
GCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATG
+
13=5A.3D(1'".2?@*&)*&/5B0H8:#?6*):+9,-/(;@;>+7-8
@r7059
CAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCAGATTATCCTGAATTTTCGGTGATGCC
+
*C?%?%,:G8H4.<=4...B4"-EA0<>>/$9&+'*-H#85%7>:#C(<80(!!%1/<=9>+)>=F@.9B>5>BGH8.:A?1"9A?03(6"0D<18+*0G"C'=A7C<=74&HF%6&#F645A"=.!B9AC-;.@39$
@r7060
ATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCAACATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGCGA
+
H.E737#CG+?@:3E$+D+>4,&,GB6)E:,'6'+&"A06+;D)@!27D*.G@(B#2)#,0>8+C12,'G)+*-&?/;(>$2)6%GB*9#0<+03@#>C=3&)4,5@5&<<:,"B%7728?9!D=5*#)3$+8(>=4A:'=7B<.'./>46)":"(!*3@A;+=+4>@#<
@r7061
ATGAAAATAATGGGTACTGTAAAAGCGGTGCTAGTCGGCA
+
?<<6F<3/A)H,;"B1>9',+%$G1.9/>6436$G==7EA
@r7062
GGCTTGNTGTTCNNTCNGTTCTTCAATTCGAATATNGGTTACGTCTGCATG
+
'&"&%&#*(*(#!&*&""+&*)!('%(!')$%)"**+()%*%#)+&(%&+(
@r7063
GCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAAT
+
16G;H&"%">@%$A&-<0/%5:/E=%2-0=E&A4.>#(/#<.48;0"<.87.&<%H75'C"B(
@r7064
ATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGNAAATGAGCAGAAATTTAAGTTT
+
D9:"5G<33G%&5CC&E@3(5!0)D5*(-++95:2D;&17!FF1+4A3+2?5)%9=D5%69@<*'2@D/6$-):)D#0=+G<H=B4(@4B4B/+<;HC2:F
@r7065
TATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACC
+
)3F-/3?A8>1A$3!12&B#%',59-2@%3*)7%G"D+%;3$2?H!A->"0+"B:*0=<*D@28%852C5!+!:'*3"D,B5$,>'5178#ED$!)$-25.
@r7066
CCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTNCAGTCCGAACTTAGCTTTGANTTCTGCGATCTTCGCCAGAGCCT
+
+.F7/+$%,-3&->@$DH&+4G0A8(/-EC"G)65H$1GH./9$)$+2>$>:B1D:FE/27%C/E898<C9!(>9'F6.$1(&/"B5F58.!%A57"G58H45F!D$H/9!G7%FB2HF
@r7067
TTCTTTTCCATTAACAAACTTTCGCAGTAAATCCCATGANACAGACAGAATCAGCGATTCTTGCGCACGTCCGGCGATGTGCGCCNGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCAGNGGCTATTTCCGTATGTCGCCGGAAGACTGGC
+
+&#'#(!)"'"%)+%')++++!('()#'#&%**&'!#(%!&$#%+%(%(*'#+&)"$)*+$($'#!+#(!'"($(%'+"*(!(%)"'"%!(+*$%+%'!+$")(&+*(!')+#$'$"(%'&**%$%*(&#)%"&'&!$!+()#)+&$'!*"*!!!$&*%((&(&&+&%'$!(%&%"%%!%*(($&&(()*+!(##"*
@r7068
NAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTNTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGA
+
!H2(C=A>//C6!249!(B/A#>5+?:$$3F*50/+"+:)F:(952/1$A9%'B"=*)8%;-:5@(2;-DE3,+@8*>*-*,)&;>6%&E/H*.$1)A
@r7069
CNNNNNGANTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTAATGCGCGGCTATGCCACCGNCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGANCAGAATAACCATGTGGTGA
+
%""!%$$*"'+(')(*!#'*&*$'&+$#'(!#"**")&&%$+)*)&(&++(!"$))')"'"")##*+&+!"#(''&*!'($&!(#(+$)*+#**(&&**$*"%("+"*'#'$'#"(""%$!'#"*$(+"&$"$%"%##(+""((&'%#&**+("&&&)+')&)!')#$+
@r7070
TTNTAANCGTGTNGGCGAAAGTGATTGCGCNTACCCGCATATT
+
"((**#)'#'%*#*"+*$#&#%++$)$%"(+!"&))*+&%$'(
@r7071
ACGTTGCAGGTTGCNTTCAATCTGTTTGTGGTATTCAGCCAGCACTGT
+
0C,%#?@<0:0!D)7AD&7./@3/"!3;20*'&>43!"B9E469#)@(
@r7072
AGAGCAGGCACNGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGT
+
1>G;D7%27A3?#58:40)EA+B@7C.4,C+1G%5=0001@4*D,C,%9"-AH3B=0E%<<9E.0EHH6ABCD,246CF,B;&CH6"&;@=9D2
@r7073
TTTCACAAGCGTTATTTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCA
+
8:G:$0474BE*.?5$ECE03@>F3/1778D,'##5!&/<!E'GH=9F&"A90)/<0;$*=-=$89<6A<&E..'8!C*%&=9!;)8(/:'$9'+-275A'@>G/G.(C32
@r7074
CGATTNGCTGAACACACCAGTATAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTNACCCGGCTCATACCGCAACCGCG
+
EGGBHC7A(.0DF>A51&7?$,&&D<1D'<GB?G2B;5!0A"A&D9)/&2G#?H>*1-;/66;4+F9'%2;G;%(3%;:!%)=,+4=>'9*D%;2G%#'6GD3(.HBHBB
@r7075
ATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCG
+
.2@"!@&(2<"0DB;+7;1<2=G</8(-04A;A$,/AF<@@HH"%:#0E7B
@r7076
ACGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAAT
+
#45;;"#E!"#47D;E39=)A?/26;;77F7)0F,<C$=A:"?DC9;)#DH$&F.<)%3%(:260-&*GHD<9A#D3/+D<-7@:02G?*C2)E2"(!;&-6(H(-(/C<D&'
@r7077
CATGCCACACATGAGGAATACCGATTCTCTCATTANCATATTCAGGCCAGTTATCTGG
+
,1)!1*'*-=)B-*C"C:%A64,E8.CF%66!.8BA-3>>8/-H3+;E''4%329F9'
@r7078
GAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACNGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCC
+
F206F@HEA$$>;7<=)B*<05.+B<8#4,#!E%<4E,*=95G:=%=--,#!,(82>.E0:&A&0241>2?6;'92-,HEA>1"&5:,2
@r7079
TATAAATGAGTATCAANGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGNGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGNTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAA
+
57$<C30+?:9FG5=<>F#"8GG4'&1+-HH.41.;+03,2>.@!.9;).,51!'DB/4=C5C1%8G?G(1E"'5G(<74!=409G7:1HE8+2E#1(:1&$,),!9#-44%C"F$.!CH8:93FC-DA2D(9?(?$FG111H
@r7080
ACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACA
+
(>/<(!4#/"@=;='E?3.967.>!")#F1"1CH0D>40!>6D">>;:(.5)8&HH=5<#&.A%B>1E02#&'-FC'-1(3=G,#-#-6$0-)$9<)H$=0>1C+GH#'F,D5B8&4==5
@r7081
CCAGAGCACATCCTCATAACGGAACGTGCCGGNCTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGC
+
2(+9*8,2:@=14D7>%FB0)%@$C+G?)$H%*%E*8<4%&5#?(D!?E'0B%5%),6@+($8&,2*+$:6@B'B"%6
@r7082
CNNACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGGTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCG
+
)%%1;+G>B816!,B@#?,-9*GG#-$.&>;HH#D1">$/>"F+&-D2HCB5B1A,*6A!D;,4*-$%#A&?A.-@))<
@r7083
GCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCT
+
5H11-D/+)/,D-.?G.074-8*!803B&D)AF+=$00!'>&GB!F979;DB<9?%;9>*/)1
@r7084
TGACTGANAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACNAGAAACGTAAAATGATATAAATATCAATATATTAAACTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAA
+
5&9<424,B-F8(#@72G;6)&C:B9AA*:7:,0+&G'!CG%.B=14=05!.H"G<!H5:6:@5$E!+G88!%:43-@?$":0"6D.!H$4@G3"7*@D<%**6<&30/2((21CC&C@!$D@@'1GH?(#F%/*./3&.,!83H9":;9$BG,*>*5:*=,!,B
@r7085
NTATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAAC
+
'4*G(90HA%A8G?F-'A#%E8>"9HD#:1E-0C2,B.3>EFGA"0F4/(:!H7-H83,=>(*590*">C(9&=@":$&3/E6
@r7086
TNAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCT
+
('8>>>"H41?669/(C1B/)7C04>E1,D0%,3A5.63D4'+3!,?<.
@r7087
AATGCNTGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCC
+
A@,152HE.F?#!G-F0F!3>'.&&?%<.FE?E##'#%$E*/06F37/@9%$F#?#H<"H.1+H"&*5EF/;+!(+G*7;A./4&?"''7H=
@r7088
AAACTCGCCATGTNCTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACG
+
8C-3@CE50<=E;#H"3:-+)9B4H%))6')6(C3/5E(,33$$@>*,27/$A9G9
@r7089
CAAAGCGCGATCAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATANACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAANAGCATAAA
+
B=.:=G/DD)*G4330'1G3A6/?=!$<GA($(>3H8!A27'7@&@/E;9"#<+:;G/*-$$>*(&67'#F'-(#D%&3-H'A*&&B=+?G58>&C9H+F=%)<D!@6=2*"*EBH+7#74
@r7090
GGAAAANNCCGCAGNNCNGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCCCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGT
+
**)%%&$$*"!($)'*'#++'$'$))""*!(+##$"*#(!%'(%$$)+++$'"%'%+(&)"%('&**('*'+')')$%&"$$(#$#(%+(%!($%(+)&+%(*!*++!'(!)"&$*)'%+$"#()(&%(
@r7091
NCNANGTGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGNGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTC
+
#(!(!!%+'+$$#($''#$&$''(&+")"+'*&!***+&%&)!!+(#'!$"'#$%)'"&!&*##'(*!"+''$)('(%(+'$!%$+%)(#"+&)*!+%*%%#
@r7092
GNATATCATCAAGGCCATGAACAAAGCAGCCGAGCTGGATGAACTGATACCGGGGTTGCTGGGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTT
+
#+)!;D>:<H;@#FD!#6/!8B'5A">HF(@7"3+'3'B@?5<*C#)):%EA6H3HFE!?&D(=',?,=3!,,>%81&*,5)0<A'=EE>-4"(60:94&;4)!7D-<E/.%502?G5.
@r7093
GANNNCNNAANNNANNANNANATTNNNNNNNNGGAGNTTNANTANANGCCACNGGATAGANAGGNNNNNCGNNANCN
+
$"#!#"#"#$!$$"#!##$$!!$!$"!""!$$###"#!#$$$!"!!!!#!##!$#"""""!$"#!#!!$$$!$$!$#
@r7094
TCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCA
+
+;D<-D6"$4;>=5/"A;A3%-6G$!E=$22+3=EG*=#A?1;)274-&;</%1E*?!C-B%G0$$A#$
@r7095
GCCAGTGATTCTGGATTCTGGCTTGAGGTTGAAGGTAANTCNATGAC
+
-=:01C)/"(((;@*HH7/FDGB313&C/6125D8@?<"<>6:%)7'
@r7096
CNGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCNACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAG
+
*%+++*'#)(!#'*%!&)"+%"()"+&&#$(''"(!'$+!+)%&+'(!(+#+"++$!%$(%)*&%"'(&*')$'%+'%%$)!*%$*%&+*(*("&'%)*%$'**&!'#$%$"'$!+$(%#$!'(($'($)
@r7097
TCCGTTGTCTGTATACGGGGAGTTCNGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGG
+
/*F";:@C'%0B3+,:.!+5746%H':0+&G.$=)6>@*/+(4<=?5$G8#F+!4"+5B/'<D4*#+$=:8H8C(F+."B29E8$F#$BE;--F,DHC=)5#0E/-C4+4>G?*A'&!
@r7098
TGTCCCTAGGACTTCTATGTGCCGGAGCNGACATTACAAACG
+
0(,9G25B"1<H@60B1@%;(5<<A+#)>8&)H2>"43-E6$
@r7099
CTGCTGCGGCACCTCAACTCCGATTTANTGAACGCAATATTNACA
+
C3@2+1G%,01(?*"="8!$4:">+5D1B*3?)1(2/@+(3/#E)
@r7100
TGTTTTTAATGAGGTTATCACGGAATCCCATGTGCGNGACGGACAT
+
+"H;0"D??@A.:1/H+<FFAC,?36+.9)$/:#CA0E25CBA2,2
@r7101
NNTCCTTGCNGANGNANGATCCCNNNGGNGNNTCANNTNATTTNNCNTACNCANNAGGTTNANAGNNNANNCNANCGCNNTCANNNTGNNGGNTNCTNAATCNNTNGNNANTNACTTCCCNGNNTCNTNNGNNNATAGTNCNNGAAATNGCNGNNTNCTNTNTCNCNTG
+
"!$$$""$##$!"##$$!"$##$$#$$###$!!$#"$"!$!$####!$"$"#$$#"#!"!$#""""""#$#"!"#$"#$#"$$"$"#"!!##!#$"#!#!"$"!$!"#!$"$$$#"!$$$"#!!$#!$!!!#"$#!$!!#$$#$""!!#"$"##"!!"$$!$"$#$"$$
@r7102
GCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTG
+
?6A>>HCC;@+4?-%A;F%'FE0,,">!+%9.2/E,=H'2D+.9E+A%*C67;G8:9@75G"49;93;,C#$BHA>)6A@(3(>/G1#%;8)5&D>&"+>""-9!D>>77$;'B?)>0""/!&7H5>,B>>>E?
@r7103
TATNAGNNGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTNACGCAACTGGCGC
+
$%"&)'%))$+$!')$#&"#"$+%)!())((("+*&&&'))%!#$$&)%$$&%!%)+*$%$*$'!*'"+#)%%")&"#(%+
@r7104
CTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAAT
+
?/E:(402*067D@#64;;E>)20!&2D8/;H!8/!3>E;G%1+5:7-D@HH@!BA/%$$2
@r7105
TTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACNCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAA
+
4&1AB/$G;@51437GAE!E&<=-56E-2>/%HH%9<2,F(*?',/7$)709D#B/*B',-HFH7)"C45*'.>HE#.F%)@"C%@/'//&1%%*?@4-GA7G*%8*/.$E+H8A,
@r7106
CAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCNGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTNCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCNGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATNATCGC
+
<C0>A0)..?#EA"/D345-:>7/<;%&H@&=?-($409!*(F4.-53@*C;F12F"#*F2&1AD3B7$0%5:3&$5F%8/',B22F)B?"+$A&%1&#"59<4;)5.?+E.3$%1B7"/A)?1D14=5F:5*A-#9CA?)6,/:+>H;6491HD@'@!=7H51'86<=34GB5*A"2H?6>F56,>;(H#6+)%@""@;$G?FGB()?836<+?A,34(-(=-5D#*8>+C'!1)D=/2$&F3FFC#@H,71.)8"7-;H21!3-9B;5)2F"C%>;)=038/#@@(C1)9(E#FA170&9'(&-B-DH/>=%7G@2)2
@r7107
NATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCTGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATNTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCC
+
";4F>6?H$-B2-)35?.$>F!)E22>:5<9!:04AG-;/-<$E+E:<1G!"87'C,3=#'H-2H:0@H2A($@H,$%(?(67&:@9?346/+@/*B$+0"@7/8F*B53&6D@<=9@7")A$'5!/4.%<:#;57<#.6*#A6-(0AC2;E%*"'5'=*'5#%B;F3+<"$:(90A*6
@r7108
AAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTG
+
6<F'B:HEA/<@A8%).:G87H%>%B<)9/9&H!B;1H(>C42?3F9B$C&-.<E('1++<0(!#%4*3$,.22:%,/+>5&ADB1H4->''("8*)2
@r7109
NATACCAATAACGCTTCACTCGAGGCGTTTTTGGTTATGTATAAATAAGGAGCACACCAT
+
#('+%#+%'#&'&#'+(('%(")*!"&*"$'%!"")'$&*&(!%!((&*)!!#&!(*"($
@r7110
ATGGGCGCAGATAGCACANGCAGACGNAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGAG
+
;6#5$H%B@009+8!3/*1%D35G1C3,"7&20DF1"38G70$2,388=,6!-C#.:>7>;A&%-,"A:5#G.8/H*#>&DDCDC@2#!$.;%,--?B"8:.*+/C7*,5/.
@r7111
AGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTT
+
F-EG(01F=:?H)2@'%*FBB3>/@)F7.1%/$,/3D)#),@*>"B>?!
@r7112
TGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCANCAGGCCACC
+
?*?+GA7C(0&=(/95>*')"'!&!3G,8D'<G0FA!5G(@)6+H1%*
@r7113
CAGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAG
+
3CC35B6C@9;%"9EG!7BG*&$2:&=9*-D(!$8.'#9"7+1@+HE%@!6D),$E&@5(A$(+0"%8."$B/H*<GEE8G"!6='@021#9.C5F/:/
@r7114
GCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTGTTTTTCTGCTCTGAC
+
G*7AG5<>A/@$@/DA3H2+>79:37H421%2/H"6%)2<F+<A%7>F4-B5)763"1#/AC8!)%.40@"A1;,A',':7(+:6%:54*D8G8*;
@r7115
GGCGCCACAGAAAGGATTTCCAGCCCCGGTGCTCTTCCAGAAACGACTCCAG
+
%#&#+%##'%#!&&'&!$"*$$*&*$'#$*#"($"#*')*"'($$*%**!'(
@r7116
CGAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGT
+
*#%+%*'#)*")"'()*&")"$%+%)$+!$)*)%%+')($$#+
@r7117
GACAACTCTNCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCANGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCANTACGGNAATAATCCGCATAA
+
&#);95;('<6('=.@?,8DE+3,5*)9!<>GB$<0G?@3D<(&#C)4;86;6,8G#FA1*H1H"H8D&DF2>E<5;-#+7+F(B8@&$,"D<=0!A<;'H"3%!51%G7>7
@r7118
GGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGGCTCTTCCAGCCNGCACAGAAACATCTGGCTCGCCTTACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCTCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCNTACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACATGGAGTAGC
+
+%(%"'"*(&*)#+&#&(+!#*'(%+&'&&")+%"$"+%&++$%'*))#!+'&%+%(&$(#%'%"&&("*""!#$(*'&!''#""$&*%*+'(%!'("$(%"+'!&#(!"*#+*"&*%'!()"'!""!)!)+&*!+%'+%+!%+!#(+%*+(#%'"(*$'%&*"+(*#(&!(&'#"*+#*$+))**'&#$%'%'*&(%"%&+*%%!*)(#$%"&()(*&%"'$"$*'&'&++!)$#$!!)#(%%&"#)&($'(!)%#%'&%&+*$&(+"$%$#"%!"*)#
@r7119
TGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGG
+
5B%DDG@,("<16?0&F.(1)',B8D/>H%36>$2@5(@.3'9:3H$):@47G9ACB@B#'3'G(17=?&C
@r7120
NCNCCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGGAATGGCCAGCTCTTCGTCACGCATNTTCTGCNTGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATGCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATC
+
!*&!+$$)*"'+)'$)"!%&"*!!#'$#**)*"+'$!#!''$#("#)&#"***#&%%&')!#!')($#%+((%&$#!$)+"'"&!)*%))%'&')%""*($*##*'&(&")"&('##'%!(&&*&"#+*'"%*'"&)%!+$%'+*#++)&('*""$)#'+$'+#*)(!$+#+$+(((
@r7121
CGGTGCTGACTGAATCATGGTGAACGCACGCGCCGGATCGCCGGTGGTCACC
+
.H;*<),)+3*292E7-%6=4ED,86$%706'67=$#;;/9.1?'D2><1(;
@r7122
TGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCNCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACNATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGNGAACTTCTCTGCGGNAGTGTCCGGGAATAATTAAAACGATGCAC
+
83G?!%6)C%G*F?6523E3B-'E6'=>9*FE2*$/49</E'8>%F'+0&A9?36*FG%A??+,@7&2-=-6#<6%(E/+.E&B9&@<?#)4;9F(H#+D*F9*45(@(@H"#2=9@$1'G;&#@<(&)HHEH<&H>GE<<#.<GC&"#D('B%0=)G<5"',:H=.(9('6G,-'0-52<F#B0A863E(!E+$:!$E!(7#.$<?,+B?(DB*2H:*-'E5@$.8-5>BH(6*@A!+D:8*<!?$4E!3*/+5$=,&0"+%-C<D&@-&0*?@7-0'"//A(4-%='<E-&9,F)++:)'G@!<.()?!#(1(+$,2E?@"3-
@r7123
ATAAANNGATNCNGCTCATTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAAGAAATTCATATAAAAAACGTACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGAC
+
))$*'!$*$%&%"()#$*#"+&(*)(&%%%$*)'!!$('(*+#(+*'%&('*$)(%#$#&'"%)&!!&)"&#'%($)&+!$!"'&'&$)"')'+!&&$')$)%++*"'#!*#'#*($+!*%%"$(!''#*!)*#%)''&("*$")#$&'*%#!(&&*(#)"+"%")'*($$#+'&#)(&#*$"(("#
@r7124
GTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATC
+
>"@%%F6G8"*"C@/$$5%(3'A6?E=1A1H/=D&19"'+'1(+&/*:-9&2/H@HB%F"B$B(<:>A,A-,.,#%&E;(*!6'"@49E;/&G55H@:(.;#&C
@r7125
GGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCT
+
,(,)F%G";377104FA;=*':H;,70+D@).:/H&F>)1$DA,)8FD&%!2G$+H&$8;90:/)1076H7/6"A-?+3<1%6FD*#+/
@r7126
GTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGNTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAG
+
>*=+D09#@%294=/>)>F"(:4%:0'$-*1B?C/BE0.(.*<625$4/F0"39%,1&!G!,#4-@=3*@'$-F=$C&,G<(<'=5CC%82)&CF3A&:ADF.,,)?A<3$1%39C?/B3"2,*%>'(*=C)+")4C?0:+G8@,2+(*,85;-C=$"&0,%-F!'+"4;0A8A;+336D;*/5?F7G
@r7127
TTCNACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTNTTCTGCCTGCCGTTT
+
&*#$%+&)"'**$+!+!!%#"$"#!$""!!&+'*$!+"$))(!%(&+*"*$'#&
@r7128
GGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGGCGGTGC
+
>"H!3/6!B<)&A$;0?;@E'A/"0G;@$AA=/%3/!-7#>:/!?!EH
@r7129
CCGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTNTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCAC
+
%!,#,FG=;"%.:&.D1$-8E@H4GG97=$&!+)E113E;?,13H!/>%C#!0898:A$8*=?<9A-79*(&@+#/."@D</2$>70!;*<8:A3:F#!%@@D7<2,EC)C/(17A1!)5!1HG#805)FD8A$.755'(:F)4B+;4,>+&7B0+0)*B-B-$@(@'3B
@r7130
NAAGCAGTGTGGACTGGCCGTCANGTACCCGTACTNTCACCGTGACCGATGACCATCCTNTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTNTCCCGTATTGTNGACATGCCAGCGGGTCGGGGAAACGTGATCC
+
++$("#+*!)*''!+$+'*%$!&"%+%(*%$"(+$%!'$&)!(%(&(&)!"***"#!)'')(+"%&%'"(!+')$!+)"##'+$+))(#(+%###&+#!!#)"*"$#($&)$')%%'&%"(%+!++*&%+++$'+*''$*%"*$!&+)!)!)''%!!#*($!)+(((&&$)'!$)!&('!!(()$+%+##+")!*$"*'*"!'%$+$($)$)$+'&*+*%)%)+)()''%(*'"$*)+#+($)*+##&%!"+'*$
@r7131
NAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGA
+
!9>4,/(.<&,)=)'>"H7*F(H7+!@GADG2@F95%>D$HEF5,-#(#:9B1?A:#A-B$$'9(?17639B+8,#GC@;)7"C!&@+,52/@>3F5E2C*49%-97(8,,9<C18)!G<:G/-,<"=F>!4
@r7132
GGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGA
+
)F,3)(E5#/,=.?%#(@$B656BC+G)+1.<1?;2EHEH:;D&(13&
@r7133
CAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATG
+
G"6<(@*1<*H%C3H:%>G5'9@1!(,,3C:'(+#C=0#>+A.F!,61";5C1$(0<)<.@A@:#&F'$=H'.
@r7134
CTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTNGTGCGCACCAGCATCNGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACAC
+
'')*')'&+#+!+"'+$##(%(%&&'(#)('%&)*&($("%#!!+$$$'(+$#*"*$#(!"($*+'#(&#"!(((+(!'+&+(%$!+++*"%'#!+)$+*$))%)*(*)($"&)(!%(*##*%#+&!$#(!"+)(!('")'%""!#!&+%+$&%(&%#
@r7135
CTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGNGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAG
+
ED8"B*8??>7;+)8$@19:0&3)C>)6C*<#)D<@(&#40G4"!9!H!<=>65#F#3G$)BB!2*0D6)9/1.(=(3!39-8F3*&;57&@<D2?;=BA
@r7136
AGNACNNCNCGTCGGATAAGACGTGNACCTATAACCGNAGTAATGTGGTTATGCCGGATAATGGCGCGCCGTTCCGCTACAG
+
")#)*!%$"#+)#&(''#&!++!!'+&)$%$$#*&&(%$*"&!'#%!"&''++'!)#)%#&*%%'#((%""#"&!('("%+'
@r7137
ATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGNAGNAA
+
9%0C0$66'4/F@?47.=.;#04&B,D:;EB93&!4,-4A<9#(1"*03#EE2
@r7138
GCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGT
+
D+&0'8?%F9D&9+89G1B"<E-C%2'5+9<8"B4:(@&4423)"*78,#>59*
@r7139
GGCGAACGCGGCAATTACTGACATGCAGATCCGTCAGCGGGATGTT
+
E143,#7*-8-A,4,5ACC%(G68C6;>4!?7)<??3=5171-B.B
@r7140
NGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAANCNCT
+
#+(+$(&**!!(*'')*!)#!#'+"*'("!#*#%!+'%$'#"'&*)*'&+#%$)+'%%#(*+%''%$#$'&%$%&'&'*(&#'!%#$*$&*&#"*"($%#*+##&%)$!)%")$"(!(%&)$+#%"
@r7141
GATATAAAAAATCNCGAAACCGTTATGCAGGCTCTAACTATTACCTGCG
+
/#65%=?8C9-3181!A(=$;,@'(CGD3BEA0'0<E+9E2"/8.=D@6
@r7142
TGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTT
+
)-+$,F3+C*@#A8!'!A4)2;1A0*&>=?&91$&E3>F+(@<179:8$.76@9E:,&!>-5A'7!#D<:>%&<7B4DA>"8H)%!-H20+93479@BB,:H65>0*9AH49.@C$:*;#)
@r7143
GTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCNCACTTTGTTACGCCACCAATACTATTAAGTGAAAACATTCCTANTATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCNGGTTGCCATTTTTAAAGAAATATTCGAT
+
7*+:=6HE%8-%91GG$7.G.'&H&<1#%9(&4E"7981*#F!F%*6),FF-?'-=CA;-'%A-5<)<5H@$+(E*'!@@8&9H6G#)32"6!.+5B&4A%7/&E#>4<F:(#F)(1301'AF-3D2"E/76G%!ABFA@8!"/$2<62(C85D2*+@F<@D,,.8?<-CA3E3>-"C=:5ED#A=();C!8-%E4A(37?3%C.%A6DG%%8$*!:!&C-+)''&H2>8DD6+9"'/.;,+#
@r7144
AAGAGCTTTAGCCAGANTTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGT
+
H,")'B$=B"7;D.;*0#%/*5('"-@.9)+)5@7G94B)E,$64+E5;=D==')G$"C>8*6?3?DG+/>*H>5G/(5!:8E.;.);3F?*04;$H8=;B?@&B.)05#)1()5=C6!@/8
@r7145
CCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGNTGGCGCAATAACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATNTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCACAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGNCAAGATGCAGAGATTGCCATGGTACAGGC
+
$EF-?):@'D#''@1&>H0H>$,1C*<!.-*')'B;D,8FC0;8D!D<C/.)):"++"D-70*4+E#7,.C4&64A-!E/#F=2@4+@45DB8#2.E<FC8('E'570G24?GH+=.<<*28,35%G?E%D(D>;6312(9!5;E,E1?!(=5";"765=1@5!B:&)"B&9*1!C%A&#:@G'$.#-)G*:2>H(++(G%)"3C1D3(FG$6)1(3/@'7!/9+?*&E7#D4!$41.%$@HF%9D;B(*B.%=-?E$2563<$;0!9:D;<C'>5&'3!6$254"!49G.11&$:5"H<;)3'>BC&06HHCC2
@r7146
TGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTA
+
G**$B=!=/12&E:-C$=&$04&A<'*0E;?3-932=0C"0C'1+9HF@B,21+B=2=HA;?59;>C(>;9,:,!3G7D;/'2!0;4-.("C<G.@1
@r7147
GGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTC
+
,><EGG&@94'=B?'(.%:D(E@42,#(-@%,CE.#H$&?*=->*:+)36,@@='070D
@r7148
ACTTTGCCAACTATGACCCGCGTATGAAGCGTGAANGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTT
+
>%G')HE+-$88F4=,<F(/,>%3FA&+A?$?):A.8:'G(7?"43F3'D7H&"7;*3*55#BE$"=2F&'C3*?)93+2'#,;
@r7149
TTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTC
+
5H"+C$;E@(H*&,H%$&4+A)(-15A/0H0+:;;<+"B$)21$;.D%8BCF'H@0)4,2?F,BHE(DH=.;20!>,C
@r7150
ACACGCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCG
+
2<.,8D84+>?D/HF#$3E179H;'H+#*D'$%&,;C$*G&('!C%H:#6
@r7151
GTANCCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCG
+
.+A&-B1*>6D+H#<"45H05+=H:1=$'(D3-=BGHA882-D#/E@@59A:G,&86!F($),>E+:A8F#
@r7152
NCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCNGAGTAGAAGATGGTAG
+
%+""%#()($(!$#!"'#!(%#&$%")&*)'*'"#"$"$%+$*'+#*("!('#*)$&'$"#)$"'(""%(%$%*'(%*$)&%')+"('(#)"$"+"!()&'$+
@r7153
ATGAAACGCCGATGTTTGTNGCGCAGGGCAACNAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCANCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGA
+
,.?&E@"1-#*&//3(:9-5H2<2=!%4#<*!8.HDH4B@)=?=%53535E77=:>A65)'#(BD,)!&/?*2?#&:/:@>0&B>A+"(D?8F/97B!G+63*<"!D!G"93$&("1:@B#.2D
@r7154
GTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACC
+
,DEEA%+C2:70-",A,%G&99F%>5'*37;/:)8C&H.A.03))#@F#DE->"36.F'9:-4&$:;=2=::?*/"?=)<.,H83!4-8H50<;:B
@r7155
ACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACAC
+
>6"'@0G7%$)-11HF-=G&E/'<B=@638"<)EB#$8*DEEF2%<1/>*''(:#;$D-54#-""$5A=<+)0BHD2$>)8)C)C"(03@017=-!BA>(1).*>808/0+@7=F+.;B'956DH*8@>7<C7'85F$*+
@r7156
TGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTC
+
)E5&F+7(0HD(30,?9$?3$.70<D#80C'=+.<-!630?78A4(0!@(!E:F>$,DF@ED)8.45=9>*0%%%5<03G-4C?*047=:/9@7!/-#:08":#(52*/(6*76=';G;559>EB$5F2G?73.C##$01A*G=<!,H>3*F54G#/3B-"1G+5G()."HF*?G#)HA=
@r7157
CNNGNNNATGCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGG
+
$"!&#"!$&'+$#'!('!$'+%())!*"&(%'"+%#'($')!$##!"&#(''&'()(+#!!'##%!)&%")!&!%""&*%"$''"$+!!!+'%*+
@r7158
CGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAA
+
C:7$++-C:=8>3%<*;D7;:H*"$3,7!,4E$)=/'6$.;F:->8H9!"
@r7159
GTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTCGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTA
+
(G+5C("&!F:>()B9-/?+*A!:-3;?##B2&A<$48F$<F1C=A8:"C#;,!2$2/>2B"/?63$:.:CG/1;+/D$E:3=7H;HB#)A8;24/D+H1+('</>+G@0)6BF6!G97HH1F,%<8?&9!9&(#>7572&-8?'5FC$:>'.*!-)C.0
@r7160
AGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGT
+
4$:AD-2D?4/"$*(")::/$:E/#G'E)A#!H-(6%?+%E57;0$,+"7%,89/:(EC)1HG/:)F'7.,<1#14?.+A3'+E1%=$$)-E<FB$>#@
@r7161
GACTGTCACCGCAAGTGCGGCAAAGACAGAAACGGCAATACACACATTACGCATCGTTCAC
+
8B5*E,7A)H:"2)=9*=7!8E!+&?.++F7/9%,2)E8%30%8(6D.+E3*?154@+B56
@r7162
ATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTG
+
5-#=)6,G0E$G",#22GB*==&2>%44>#;00C86F1C1<3'7,@$G>1.:D>%A&!*.)A54>HAAG5;)C1
@r7163
TTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAA
+
G632C,A+&;*,=A7;C031H3)550*)9/,619FEG;!+)FG?--&DB8"/&G:E;6)1?0H78''5>>;)-4:,7=50D<F:BABH,-FB"?H!!53=<$53::7*2A'2@%
@r7164
NTTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTC
+
'++&&%*&%((#)&+!&*))"&'+&#)%!(&$%%"%!$%$&)*!'"!)#)&'&'%+!%$%+&)*!')*'('&!$"'$"
@r7165
GGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTCCGCCGGACCACCGTTCCGCCGACCAGACTCTGCATA
+
D@'7E8E7H3#';4HE.)-"/&D49"2,0&;5E=?$6/&,C)5AF2?7,).9'E,<9('48.C585E>E-44@#/143G628/%-5+HEE(H77=.,1:-9H6;5C&8;7?B)($EA.""/:1.9B:C34#'?510E29%G&9E';&%/&?))./9A?:=F(!9HG:@@?,5A+!F/1!?#*=5D,"9)%8<2+;4#F(:#(57H%8%?*
@r7166
TNAACNATGNATTNNAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGATGGGGAACTTCTCTGCGGG
+
!"*)&$#)(#$(($%+"#')++(#*((&&!)*'$#("$*(#$!%&(*"*#)'"#"+%(+"&$!"+'%%)+%*$$)#"(#+$"!%!'+)"+'%#)!#%%+&#'%!*(+)(#(#*##$**(!%
@r7167
CAAATGGCAGCGACGCACACACCCCCTCTGNCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTT
+
G&5="$*>.;)??'#(4+2A-@+/B/%G>?A4#,2$9#H)*A7B8:,)7,+:5D7@(&8-)"@/61E=39@<F%9(./@=>
@r7168
ACACNNNTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGNTTTCCTCACCCGGCCCCC
+
)**"%)%'+"*$'((&+&+$''%$&*(%"&!+*&&)#!%%*#*$#"")$**(*'))$'((+#*(*&%&+'!)*#$*("'%!)$)!$&&+*"##"$''$&(&#*"+%#(&)!')*!%"*#&(%'$++#)+(**#"'$$##&*+"!+'''%&*+&)&*$()&$&$"+)"('!)'&#(+%''(!
@r7169
TGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCNGTTCATTCAGCGTATTCAGTGCGT
+
D,A*H+3*58BG?G#7D'"B-6&G33(>="*D4->14?%9F6):D@:H8GB3?CG7@26,8F7
@r7170
AGAGAAGCACAAAGCGTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGNTGTCAAACGACGCAGCTCACTT
+
A<2!C!@C++)2>:=A.GE/=7/:>3C%4.*#A!,F0FBH2.0=?ED0E#(.<D$+<HB+C-&8D0$43B=$7/&>0%?G3HCEE0<*C"!3.%2DH1%"@#4D1357
@r7171
CGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGT
+
/BG9*.5<FD3.=?2,!%!$C521--%1:BB)$,+&':A/D=>)8*(1D:$:5+%D8H+5:-
@r7172
AAAACNCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACNAGAACGANGCCNGAACCCTGTTTNAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCANCGGCCTTGAACTGAAATGCCCG
+
@+BE2&DF+,%$=/71FB483B>E9&G/96+&.)7B4%5E-%;C!2#??H2(+958#9,2H'C@<;<6790==-F#()AHF'*5A36B)BC>;85@<>F''=2/A.>>)>"*%-"53/(D,96.=".79C';3?2$G+C'E&#?35$01!=7;A7<D&F7#&%G56*,F:6?%%)F<'1+.E(A.99D@@DD?0=HA/CG(,3DB8:F3-2>7@$$5))&<8:H#H:&@<)G$B-*"AB*3?G,66F>/#)%B"(,3+)4=E0>%(<H0B%?",
@r7173
AGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTT
+
+/+;A$.&,B/3(*9>"G/.27</G)>:(;C03FG#("D%+(;':::</C6/4;7-5D($<9&>
@r7174
NNNACNCNAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCT
+
"&##"#)+"%("!!*"%(!$"&*(')*$*)*####"#+&%'"*(((""$%"()&#()&('""!(#""##*)')!)%)#+'#!#)+($*!+$(%*%#"+##$)(&$%+"!+)%)*!%'&$#(!''(&$%&$&%(#+)!+*'$
@r7175
TTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATNG
+
<E#4!7"3:@4@''?)HE4/@*@<>&*A0:$6'A:8(#4A$<-2F0/D-BC@:<8=#5,A+H)$899@$4'%$H&-
@r7176
ACNNNTGGNGANNTGACGNAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAA
+
%$$!#)()!&$"#'(*%*%&"#+!#+#!+%$''+')&+)#&+$%&%&$#$"!)"!"$)$"**
@r7177
ACATCATTGATTNAGCATCAGAAATAGAAGAATTACCAGCGCAACAC
+
4C#3D"3AF5(A=:G,A=C?E:&<2H&3!/":664'778B62)=&8B
@r7178
NNGNAGGANNGCNATGCCGTTCATGACCTGATAACTGCNGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGNCGCGAGTGCCTCCTGGGCA
+
##'"(%$$%#"(((+'!"*'")''((%#)#'$&&"))+((*$%#*!#")%(+&*$&%!*'%&#'&'"%&&!+&(($&%$#)$"'('%*$*'&$*&&*%&*
@r7179
TTGCAATGNTTCTTATCAGAAACCATATAGTAAATTAGTTANACAGGAAATTTTTAATATTATTATTATCCTTCATTATGTATTAAAATTAGAGTTGTGGCTNGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGGGCTGCGGCTGGCNGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTNCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTT
+
(5)%.E3G2D)38<F"4)D%!6)'!9):!H6"1G/*#9D<31$F1A#.1#B%E1(?4A?04=E75A06.-A=)1F/12!:*2#4;-'!*3&#81#:**::&,%?81EE6H2.6A$*@615$DG?4!5D'EH%@).C&C<D,E,;=0-?62;(-B:E:546,H-&/2.@0==,"<5)3/*7#E$%?A&B0;6<9+3;03"42.<=?0-E6A'79;C.!H5991$>*3(:G.4&%C1#%D6&.C0&=&H698E(=(#B3E,+
@r7180
TATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTG
+
5D57023;=."D374$>%F)E$=430!501&B:.0H:B6FH12:+.D3)%=?GG1/!;H.-
@r7181
CCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCG
+
?C#H12!=A"GF#!+G(9/9=E+G((<AA>9B59@G;'.H;4'&DE/0;<7#/!
@r7182
ATGCGGACATAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGANACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTA
+
?;B/.7D,:32>4H@7DG$H+.$A:,8)C)%=3D.?BC1D/:*2C8*$65E+-47,&H)B%0A09C7(A,D=()=*!F.%GG8.@8A?0B+F"40)G:
@r7183
NNTCNTTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGGCCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATNTA
+
'%$$".'(D&<36E"'FC.@=3%80A(!,B@$(;(@#G?3G?C#CB96.E:F4:=#(;)C$C=>F.#0?9G%<*.3:>/=F:*('$5D4#BE9G>4!(?9G8F*''A/$7-.E#3(-'=->"DF11H8D:HF!(-&#.0+4<B/>+&<#=.&>?>31;&:'&B#%'+,GF76#!+(6?4"9,>=?=;;6#,5E5#;D4'6<C4"=@?9)"/5
@r7184
TTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTNACAGTACCCATTATTTTCATGATGTTCTGCTTGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAANATGATGTGCTGANGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCCATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAG
+
4@C821'=#8>#AC!>">:16$3,/*<C$<(AF=1(A),DCH''$*4EB3)=06!@C@8$/'",03>-#32(6D90-3C2:67A8:#*+3F2A<0C7"0'%2E9A<+G7D=?(650+F%8=99'.;!$5),6':)C#"%.<-DFA():"H;.DDF=.07=5%E8=.H%"&6+?1-<6!F(@H<"8#HCB=6!=8=)39B/A24=B,/,;A/&HFE(F&>%@.6#/<61@:2B("8$%E%#3%EH,6!3'"'+)B-F8(#6!/93$F5H'<,C4)=E<86.?7%G@5G)E+))*:900@/*CBB&)&6F%F?$*D-D$CC$/"=(!82$F-6:)G0GB0$,-/10)4#@,ECH*09H4-(HB8.FF3(4F1<<3<&F/-#C4)&=/6D49,:?HB#5AE%<E$+GE<"@2?B-74.!(!F$65E3CC$&"7H0+;-39<:H#66*@-/E013")?#H50':&@$,#A:C?7*6!7$
@r7185
NNNGNTTGTANNCTGAANAGGGTNGAGNTAGAANANCTTTATGAAAATAATCTCNGAGATAAAAACA
+
)"#)#&"$&(!$'"&')")%&*&#!''$('%*&(('*)+$%%+%('+$$$)($#$$!)(!&*+)+&*
@r7186
ACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGACAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTNCCGTAAGACGGAAATCACTCCCGGGTANATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGC
+
$+*"&'&$*"#$&'$+('*&+*&((++'&+%(+"#+*')&)""$'+"!+#+$+&%&)#'%!"+&*"&$#'#*+%(!%$*)*'*$'%+#*#*"&!*!#&+#++"*!*%+'&$(*)+&&&!#)!+!&)'&%$&&'#$*$!#&)&)!'#(!(!%$"*"$)")!$&*!*"#(#!('(*#)*(!
@r7187
AAATTGCGGCAATGCTCAATNGATACATAGACGAGGGCAAGGCGGCGTCAGCCAA
+
;!&?.:<6/+<&'(+1!A:33%BA;202G*B688?:/"F5?:AC?"5*/6,1!6G
@r7188
TTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCA
+
3C8-(HA7.)G-!H@8?(HA@C;E@-3'C&$:*C9/06D$08+H83!F8+)3'=#/7+#>6#+$'+!-<?%
@r7189
NACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGNTAGTGGTGNTTCCGCTGACGTTTCGCGGAAGT
+
#)@%F"9?)+163&G"2D);/35-#6'9&49##/&'91-?F92H6!@!*BE-BA*'C-!88-0H41>=C7%0/=$3HB"/HF&@1@A"&EFD&
@r7190
NANNTCANTNNNCTANGGTTNGGGCGTCNNTGNNCNNATAANCCTNNCTGCTNNNATGNACGGNNNACTNGTANNCCANACAGNGGTNNNAGNNCAGNNCGNTNNAGACCNNNCGNACNTTGNNCNGNANTNCNGAAGNNTACNNCGNGNCGANNNGCNACNNTNAANTANANGGGGNCACNANCNTGNNTTNNT
+
!"""$"#$"!#$!$!$##$"!###"""#$!#$$"$#"$"$$#$$#"#!#!#$"!##"$#!#$$"!"$$"!$"!###"!!""#!#$$!#"###!"!!$$!#!$##"""$#!!$"$!$$##$$$"$$"#"$!!#$!!##$!$""$$!###!$""$!"$$$!#"!""!$"#$$#$!$#$$$###!!!""!$!!!#$$"
@r7191
CAACTGCCGGAAAATCCNCCTCATCAAAAACAGCGGGGCGACC
+
+#)+%*&#*(%($(%#*&""*!"*'+#'#$*(*(*(%+!!$*!
@r7192
GCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACA
+
@D&;<CF/306*@.90@%2:HD<BF!.)*56.)EA&*=A:5*A/"3
@r7193
ATGCCATCTCTTCAGCTATCTCAGTATTGGTGACCTTGTTCAGAG
+
+>71#)+A;"!@E->5/E/$>H$&-,F?;02B6';H-./%7F!&C
@r7194
GGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTANGCTCTATAAAGTAGGCATAAACACCCAGCAGTATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATG
+
;?:3B*??(B,+B"1BB2"="+CC?H:<(.)8<07G8@+:?"4,.0<3(>8A=0?+30D*-#2<?*@1,%7!B6,<F.232E8DH23*:$=:D@;,9=>52:*01#'8<;?@+,.BA1@2:7,9,B=G<D;@"18.G9-;)5#:A2)2.>0%-(E/4)B"%:"??+)F!2/&#C-10<%@/,%;23=EC&)7!93?7!66D5@33='G'@-2$>;,01:(13.A?
@r7195
TTACTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACNTGGCTAATCAGAATTTATATCCGACCCCANCGATGAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTNCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTATTACGGT
+
&$&G%DECFC?;/,9F;B?.#H4=B4@3H7B:)7B*D!*8+@@H=<!6(>#@(4&G882/@/1;CF?F?8=A#BF<@)$#)8)8'3HH5#>1:/!A<'3>462<+H=@G1!5)B'8$0-;-/E'@>>=8'HC$*;%6+:DB,8:HE%A2-/-&#&.4E>)CF9!A,BH.>)D@)#ECD83*=&AB?:0@/G$91AD51DH=2G@G(.A$3A&D;F8+B(4;8%8&,?"2&?FA&:;B%/&8CE2DD*(1<;F544$70E6/4%@*(%B5F%;,!;;B1&E=!C?AA(4011:/0%$H,:%)!;D28#H
@r7196
ANNNNNTTTNGANNANTGCNNNNNANCCAGANNTNNCANNNNTCTT
+
"#!!!""!""$$"#$#""$"!##!""""$""!#"!"#""##$"#!#
@r7197
GCCACNCTACGNGTGNNGCAGTTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTNAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTATGCCGCANCGCCGGTNCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGA
+
)!#*&#)'!*!%"&$'$*"(&'+(##'*)&!$'#'()+)'+&''($!$'*+%'&('%*#($%$+'+#"+)"$'(*"(#%'+&*"'+(%&*#(#+'*(#$!$*$$!#"$))$')'#&$)"#!)$#)$))'!*'(##%')"+'&('&*($$*#$+!)"++%(&"+""*('"*!%+)!#%'$')#%$$&"%'!!%+*'"!&&*')#%("*'+'#($("!%"+#$&'")$"
@r7198
GCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGNTAAACGATGCTGATTNCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTGGCTGGCAGCCTCCGGCC
+
*)6"D2E.%$%9;84(!C,&?<!6/4;DH"EEEE0*@6!+>A63@5=)A:$?.1$8D%$!.8.'.2/*"/5=/&(H%81#53<D2';@!<.?.8%*.CHB1/&:39
@r7199
AACNTNCATCCGAAGGTTGAAGAACTGCGGCCGGCCAGCGAGGC
+
'%!&'$(#%&")%+!#$(!+#!&%+#%(!'$+&'($#(&&*&%!
@r7200
NTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGC
+
#'DF;*<92B07H!7+G(<<.?+./'D2$D.8%5%G.H,@%<A@2G-7H61:9BD%9,115C!C"1=*0E2.6B,(/;,6H<(3,.634*B2>6%;7F<7:AC1.*AH!!5:&6,)<13E7.+H5$1+C+A@%50>HC7(!(8=#H87(B+;/C-9%@&>B6A"D/*+,F-F
@r7201
GNTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTT
+
##+#*)!%(%''#%(("+*&*%'%$!'+)%!##)!"%$*)#+$)%"#('+(('))+$&#+)$$)'&#'#$!'%"('"
@r7202
CCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGNTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCT
+
)0!#'H.%%5E(.'C<2AG50G4G+*+2:C&5.,-9.7,6)4B)<60E**,/)4#DBF.91553B69.2,".9395;06,+=&*!
@r7203
GNCAATGGCAGCATCGAACAGGTTATCGAAAGCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCTGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCAC
+
&!<1,!67D8<CC$C%>6"B$$3F;5A(4D=;9*;#5&E$>&.:C>08.:E?;3D45"4(44763;F='=B/A:8""6A88)='8(&"167+$4.B9D5+#0'':'1EHFC-F@+@=F))>B-+1,>6<=8@<'9?'4E<:(%4G;?><%6+(1;+D;*H*E-8CC4=7%6$B.A>=HE6G<:'B
@r7204
CAAAACTTGCTGTCGCGTAGCCATCGGGTGTGCTTCCTGATATGCGAGGCTG
+
@F=$C-"0?D4:62,3G+:D3:H*6B.G4<"7&@FF<5A(!4;;F/?8,6?>
@r7205
TGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATANGGAAATCAGACAGNAGTAGCACGCAGACTGAAA
+
7B-"HH;=AF0A:4=AD$D)$E92=1*91-+?CE:"=C$4D/,;0&$F6H@G'@2G3':1B:,18)FED23:A(EBF1(?,%:DAD?H3@D7F'6?=8&'<B14%C=B2"@90$63D3ED8$H:HE)5H1/?0@:C>DB("H2H(E7C)
@r7206
AGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCNGCGCACCTATGGCTGAATTCANGATGCGGACGCACAGCGCGAAGGCATTAACGCCTTACAAATAAACAATCAAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTNGATGAAGCCAGGAGAATAACTTATTTAAAATTANAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATT
+
F.#G3$@9$8%.!%!!.A6G:E6@8;/2&&=0@#98-+F))*"%5:;E"7=B<<BCC&$E%7-.=$115E;B8:B;93-@%&:(22AB>#A'>B#7G'@>-F=<8#G2<:?,$=%/$<02?@D#&<0.10=6:@;<4%C7.H4*20?=E!9:4:9,%8FBF@(C+F/H#$DE"H*%G!<0G&2/>'D)!!;G'-@$?FE&.+;9F662C=;-E"$H508C,@1+7'/<B:#%$,E"AC@/"C#D72:.;8:%2A")>82*3$3+133#4/(A.!)+(/*2G&8#2%E9HE
@r7207
GCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGNTTCCACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTACATGGAAA
+
9:E6@<6A3>/8EFB;,:5&=C$"&!4"D:5=#"<D@C04%24!A09%<6;.FHE5FG!;!7(E-83@H*/;&=@)G"ED;*'9'G%50#9'G(D4+2+H;>+""/#E6#FG@!-%F/-E"&+'H%./#0-=!D4!7*%B;9++8F:7+!5>:3HD,F,9BF,@C;&@/@#&+;2H/%H74"9=)F-.?)*'-H(/=9+18H))'.
@r7208
GCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCC
+
C+97&A39,?9E6D-+D/*$"?%@HE-:HF5#E23G0G,;?5H
@r7209
GGCGAACGCGGCAATTACTGACATGCAGAAGCGTCAGCGTGNTGTTGCNGCGCTCGATGCAAAATACACGAAGGAG
+
-GH+3G$4=!>EG<3<?/,D&#'"/+!CCF0!FF60*A391!7A>C<F=+'"F-F?+-698:?.@-C.4"=>.D==
@r7210
NTNNCNANNTNAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACT
+
&'*!)&"'!&!#))+)''(&(&$)!)))++$&+(&+)%!!!()&(#%)%#'$&(*
@r7211
ACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCT
+
H:"84:%)&#$E+-#@D.90&8!A(?=A5%@;><2)=#='5:;1=79+H)4:G=D=%-+-*"*:!0?-4E%
@r7212
GGCATCAATGGCCTCNTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATNC
+
5.:+4@&)AC<G6$G'D%A?5A#443>&0;$A6/3+2=6"<D9"=30%%469=(.@G8356C>769!=46>+'1<-BD6;C@F'A8+=>"E(3F=?6?<H$#9546)'2"!A4#39-E)
@r7213
TTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGNTAACNCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATC
+
=$(@A4-G6,%*E9D*/(@&1/54BG:-(&"6&B%-%#,!3@('(11.H#2B3;E5B39F9?>#EH?2%A$!=#>9@'4>00">A#4#G.EGAD>C&A"D+((5,:@%>)D>-A&3D%G-1(."!$%D!G(&=9)'-(E@656B1)3G:5C4='""5+D?2.0"3%A0FE92B"#746E#G2!*2E3D,045
@r7214
CNGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATCTATCACCGCAGATGGTTNTCTGTATGTTTT
+
)+#%("%#!*(!(+"%"+$$('*'%+')"+(!%%''%(%(&&&$#$*&'"*#$(&'(#$'")$!)$"!'+%$(*!%%
@r7215
CNAATCCTTCCAGACCCANCCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCANCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTTACGTCTCTCGTCAGGT
+
*!&($+%"")')(+'$#*&+)*!&+))$("(*+)%#')&"('+"!!*+($'*')()*"!!*)(#$*$("*)(#&!#+("$*!+'(*$&&!!"!#+#$')+%$(!%(""$+$*#
@r7216
GTAAACTCATCACCCGCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCANGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATC
+
24+6/!%$38.E%1F2A+6?2=%.>:C/";(>-*,57"@:-3@C--4&,<9<;+!/8./4"5=<>&8&.C"0,=9GD7D!FC)>(:?(,1$EGH&D$E,&(71+B,D&6F242<C'7+E"1?##F)@)?F42:=>G',@@5$%(A9"#!?3
@r7217
TNAGCGACTACATCCGTGAGGTCAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAG
+
"!G83!?9H&(>#"F03A050EHH=47-,;/G50&-96E,D,AE$-8FA&@467'B#-'$51(GH")/4A9,!+G%4EA.A6!?:-H$+;B?+!-&C$C'&
@r7218
AGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGC
+
6">;'D=$*B)9@G)-5;-@349:F>5+5'F7<3+16:5B50(E664*>8&41'H'((H/(A"?$E6F47
@r7219
TGCTNGNCAGTNCTGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCNCTGGAGAAACAGGGTGTGGAAATGACG
+
)')*$*!)(*(%*!)+(($%$"#($(!&$&*%'$!*#%*!()(#&!$(%+!*%!'&)+(%'#)'&!"%)!$')%&!#%!&&+#'!!#"$&!'")'"%$%**&""%)!"'"$%!(($*&$+$(
@r7220
ANAAGNCNCNCTTTTNGCNGNTNTNGNNNANNANTANGNNANANNATNNNACNNCTTANAATNNNNANNGATAACAAN
+
"#"!$"$!""#"#"#"!""$"$!"""$!!#!"$"#""!!$#"##"!##$#!"#!"#"##$$""$!!"#$##$"$#$"!
@r7221
GGNGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGAGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCG
+
>A#=%#6-%4<A&#9;D,:./F$+.!A82;44.2,)((>!D/&A5%H#/#9:1,@+F!;>?(/E34D9G80*&9-;'F9/@/%$2"1EA$0>(D</#@),F45)+10,;(3C")=$+;46"6?@99E'EE+*C0@+0:B!70AH3:21/91*E=D1<&&CE=;9@%,;3$F&63?11#<=7/,-.E$@B+(;G/0:@5,2C:%2C-'"&<%GB:B@:5EA;C"'"0C2B>7*=FA4=:;9<?F#7$#30FH5CE#8A$B=2G/(/..A@G!B!A5*;B?&H#B/*$.3?#6A75BF
@r7222
TGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCNGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGNTTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGG
+
-&A<G>23;'$&$"*?1==.:0F:2".DH?D*;(517D1&$63!:201GE<$B::-8>;-5F9<!1.%:?8@;<F/;F*75$#(=,-G61*%:.H=A",EA7<?D%=<2@:8#:+;EC51-.F:8#49B#F&==;9/,(4.=3)-2"3:E/#(2)51/D6?G@;D&.>'2+!#!61:;G4*3=(%;GB1@17&@;6@)$7&F7,$95>D*2$D+<3@36-8!:G:$E5C1>2.?;+0F5F55/>#.D&:0!5#%84>1.&A>4()4+-3<0:4:2.F)8,)9=B3>E95<(,##+*B/4E:4';;$%7=1>@<;">5:"E'#E.)D"9'GD464C.BGH?>@-68(+:/!05+<A'C&2
@r7223
GCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCA
+
+('$&#()%%#$+#"))!"((#%($*%*+"*&(&+#()#+('*!++$)"+()$))$!)()
@r7224
GTATCAGCATCGCAGAGCAAAAGTGCGGCAGANGCGGCGGCAATA
+
<%7<)DB?D3>)F>)0?<):&B0;@#93C7F=6C>EE=7=0G,,3
@r7225
CGGGATCGGCNCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCA
+
A)14/%;53<,/6BF!94)7DAE#3=>AE2A*6:G$H,=*%>8E8/F
@r7226
TAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCNATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTA
+
9H*6=4A73/49=G8>$;/$6"6(%#:5H&&E28!4B=:;4&"$4AF*D":$)6?%"1@"B$.D=*)?DGD!:=8+D$8>@559G-?&=++8,51C+A#)#B;D@>$(-@1)>;&B=4$,<<%3>?"H548..4416&$(+"7//6&?C@"'5=6/*>@:0.?*++H)
@r7227
TGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACNGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGT
+
C1A:<BG#''1$!(;*HBCE-$%CF1&H+BG>+/.!G:0==FAB@*42*=-H)A*7AC$9<+305'*A8#GH)A.32-)"%!;*%1-F".F<5G3:*-,/FE)8=2EA3D7.:,B!""B.$>2*<'==.H7(9G3>=H?H6.&$8G3:A%GD<")*E3!99#F1'G'25H*"F!01!;-40.D4&
@r7228
NGACATCACCACAAANGAAATTGCGGCAATGCTCAATGGATACATAGGCGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATANCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCCAAATCAGAGGT
+
!2(8::"0*G(2'E/!?+<3;=1!90E:BF;9=!88#GG+.A=H7$-&$5@(>!@;(=;9HAF:*H$4&2+?#+#&@D0CB='*D)<<*A=&A:E94E';;;+/!2D.--.GB"8'H72<,,HD<B81.$@80&-@C">%!/88;?B24)&226D?A813G4&"&?6@<D5%H5
@r7229
TTACCAGCAGGCCTGNTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGT
+
@GF.$/";(2@CGF@47B6=<82123/#G.<;4H?#:7/4).C$40)>#%,)%F@6.H"))A2B*4?+?.!,&
@r7230
GCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGT
+
DE;D#;'.D$642&+:45='/21:0%&B!4>:5;(%?A.FD(5%)!'ED!'?&>F?==&'A)6@#!(C96:-05$2E/'1/5>&86?+7EG4+7;/
@r7231
TCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTC
+
FH5$)4B:('B90@'1#>$G*831H".G6F?/7:F2:/&.&"#:<A>H0<GB?38;,C9BA=98A>)6H0!'/F7E1/4:?
@r7232
TTGAAGGTAATTGCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCT
+
>D!0@D%>>G=)=A'+HF0=CC0,$>@3"8(4;&?@<B)?)F2#B!B/+D$.%-EFF2?4!$:*#E0'3<>%"D$#!:1(0$;?<G@9@6E(H!)H@<296;7=4)>!=7)!-/F'C"&6;/#-88D#?6>)G"6*F7
@r7233
CCATTTCNTAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTNTGTTCCCCTGACCGCGGTTGGTGCTGTTGGCGTTCCGNTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCNTTTCATCCATTACCACCTTAANCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTNTCCCCTTTCTCGTTCTGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTNCACGT
+
('"'&#'&&+%(!#&"%!(%*)*"#!+#+*(%!&*+"$"&%*!)('*&'%+%"$'&*%###!"$#&*$!")*#!*##')#"*(('"#%"&+#((+&#+'(!(!%!'%')*$!"(&*&*)#&*$)#"*#("+(&+"&!'#*++)()($$)&&+"%+)!%+'"'"'(%%!'#*"')"!'+*%!#$"%*'"')!'("*&$(!%#)#)*')$)+&*"#)"#$$)***'$!")!**&('*%&%*"!$&%'"*'$)#)+&%$'%#*($"'&&(%&##!!(&%')!###"#++!+*&++#(+''%'%$$"'#*#)"!&+*!%'%!#&%+$&#!!%+)#*!)$%"("!!+'+$'++%&%+#!"&"%
@r7234
AGCTGNCGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTA
+
&2'GFE46@HF>;-<";*7'33B!*?F3:1@*#D,4,"+1,043E,F@;+((
@r7235
TTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGNGGTCATGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACANAAAGATTTGAAGTA
+
G5D=%6"6;):0%'(#(@>=/91D"%4D/?E6%<,?DC>%+;)429&'*D8(:EG$:A9><>-7,16:-(H'@G'*3*9/6$A6:#;"#48$BB2*94G5?03(-5:0!/1#-4@B)->!*F!1)1=.!?'&<>0A$8;F&<@!>/261C.$G7'G8:#@899".A'D9D?)-)FG<F?%C.D*9
@r7236
GCCCCATCCCCATCTTGTCTGCGACAGATTCCTNGGATAAGCCAAGTTCATTTTTCTTTTTTTCA
+
H66@!*;7BCD"2=3F+)1$3?9'"!'G"!0*,D"6-9;:6)C;-F=0.86#F*75&'"4B$H3&
@r7237
ACCACTNNTNNNTGNANCNAGNNGTGNNNGNGCNTTNTNATCNNNNNNNATCATCNCN
+
$"$$$$!!!"#"!!$#"$!#"!!#$$!!#$!!$"##""##$!"$#!""$$"####$!!
@r7238
GAAGCGTNNTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAANTGAGAGGCACCTGTCAGATTGAGCGTGAAGCCAGTGAATCCCCGCATTTTATGNGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCANTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCC
+
&$$'*&(&"(+*(#%"%&'#(!%"%)#(&#'+"(*+*!***!$'+&&+)*!%"')(#'&%"%%"$!&++*%)*+$&*$"*(!#"*!))++)$!"+'#%)%)+&##+%#'*(&%'(&*%'&"%#*#+(&+(%##+*$+$!&*""*"%$")')!"!+%+*&($*(!'*(#"+*'+%"))'()&++'$
@r7239
GCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCA
+
A0>:/GG1.G;H318%G-BF/,='A@A=.;B':2#F'0$&
@r7240
GTTCACCTCAACGGCATAATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCNTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCGTCGCCGA
+
/-4>?,$6@D39(D87')FE+113,.>;./1D01GA7307!/A4-?=D;0B.3$0DAH7C()$E-6CH,<E0!5)*"2A@/5A13E7$8B3&7:8"F:0C+%&#"EE'02)B,H3A3&4FFH7**G+6:FBF.0C>6H<<:,!0:$H5>8D;0A'7?=C;#@,?+(,6?3.B>,!
@r7241
TANACCCGCACAGAACAGGCAGAACATTGCCNTGGGCAACCATGTTATCCAGTGA
+
''%!(#&'!+)'!!)'!"&%!!#&!*!#$**%)+#+)))'%(%+*%"%*)+%*#+
@r7242
GCAGATAAAGATGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACAT
+
;$!'9DA'9>3H:#EE4-A4?F=C:"A0)HD4H+%>%1?F(.%(!<#F85*G'H:=+#
@r7243
CCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGNGTAGAAAG
+
2$'/;DH()-=@CD<D@)(@;D8H!7/;A"@F+)7H@3E20D5&&
@r7244
CAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCC
+
?5D5-0G*;,:C/0,B#0D&.*$H.$+68>!.C2;=CEA"'E&D5!@CFE!>)28.'("C6;1+E0*<98CE471&??:8A@?41B=G2.42'H?)6C;/2A3/382AE(9G6)"@E06">9)D%'(
@r7245
ACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATC
+
358'":028"'89,F#(/;*8C-)%>>0@+22@>-+)EG*;5B22>'C+&*)<"1$558!/)="&,E)$:H1%133"DH%'>#(8'B4985&*@0&8%.'EF,:!<E
@r7246
CCGCACTTTGTTACGCAACCACTACTATTAANTGAAAACATNCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACNATAAAAACGATAATNCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCA
+
$43EC/9;FE+@"!75>$3?"HG'#%C#EA,@F1/1=$9E.0H$G19%==+?DA%#555C'6(+FE5#.D:!=/E)49F<AH02@,-C+1F>4E5?=(C87$7E8=?#!D2*G:0;#0B<.)H?15$*1*#7;!!/F1F&C-0&A%F/#+GG9?
@r7247
CTGATTAAAACAGAACTGCTGGAAACGCAGNCCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGNCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCC
+
$A9E!#?8-D?:=$:E+'&A9?;383C/4<D!@.'D&H1G>=CD%='%HA(/19$-C@8&1B=2E<,.:#D6)/6/!2B(;-91F&71=GE>E/F.%<65@%C<.0>F@A;'B#0G;8?H3!0<35D1?%-A"4,A<=284!':7!(H/$E)='17/E0B)/16#GG2@DBDE)2ECFB3;1>D3$C<"*1$$CB1,9:44&H)<@)81'19%,-9?%&+<-%.%H'9,-H>G)E@!30%)CF>1!A/);.)5(>5"GG5;%G6H(,0'.A#5<A$4A*9"6>!/08@,&DA
@r7248
GAGGTAACTTTGCCGGACAGGAGCGTAATGTGGNAGATCTC
+
-.6/@&*C46$EA*HCB-</,1/E(DH(72H9B@#6+".5'
@r7249
NNTCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCNACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCAC
+
'"%C"8%$3=@9(,AGGFB@$0?A/-+<''EA&5"/35-<H?0G5(=*3!AE7D112-7"18:2/35%4!+"E@@25>'&.E=9#A;*;&6+'6#;B(8.)2&;'@*&0$#5#8141<G6'=52?2@<;#*-<-GE2:@23"H.,5:,<?((54$"2H?;#=2:"14$E!-?55@EH?<G'+G<&:D%;=/A7AD+*5&@>/;5)),(H#(46!026<?%$+$-%CC**B<#
@r7250
NGANCTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGAAGCACACAGGGTTTAGCGCGTACACGTATTGCNTTATGCCAA
+
'(%#*$'+&&!!%*%&'+(#)##!'#"+%+%&!)!)")"&+!)((!'#'"&$"&*%'*%**$'")''*(+$(&#$$'+#*%+
@r7251
NGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACC
+
#,2!<D'D85@=!%/&>5((G'>&-H<8+:2*7G%62,."A>6"((FA(?09DEA3)<.<C8G&'E!D*D>),/;9=7>.*E6D+9*?1+1@<"%5H*;@45$4@C'*0C.)*28?94"'E1D%)=5B*2&?
@r7252
TCCGNGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGTTAAAGGAAATGGCCAGGCTGANAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGNGTTGTCCTTTCGCGCCGCAGGCGTCGTAA
+
;9DC>%BG*0#-:.#"0E:-C#H(A53+E(D1/7+!@G1#<).4D7>0E<!89A3%$CED26*H+%1$D@*66/>+.#4%(#04%A8>;5&2@85%3,:!2:C@G#8#":0=-**&1C*"">(,:?EEH80;'>1DD=!.,("2>"?1/(9!C$G,.H6*@)844"EB8<>4GE74:2"D>)%)-3#)(?*8@,
@r7253
GGCCATCAGATATCGTTCCGTCTAGCTACGTCCTGATGCAGGG
+
%-4(:DF6EF5./3@A1,G$22DE;%A:@69#97C-'B@<!-?
@r7254
GGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCNCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCAGGCTANTTCTGAAATNAAAAAAAGCCAGA
+
0,4<%AH(4/.<;0,(6@0+FB98337*#)9+=$1+#<+>AC%B4BA/H9*?)<7%-%7&)4#<033&B+!6*%3@.@0H>2=<:8?2)40:&@?1C($8=$(9::2G<E"2"?(5'=111G(1CF#HEG*'"?908G7>9$
@r7255
TGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCAC
+
8&;-@HC5.!6GB64F=(9A#-2E+<)(#?%FC=$+2A8?HC&E?C5<H&*)='*=3(E47A040<7%-"A931G?11CC%.9AH'"A5?B3*"9(G<06;BD@700H50?(>;$3,BD*#H>H(#3
@r7256
ACTGCAGTCCCGGATGGACGCAGCCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAG
+
EB"</1:$(%'(3.5B/@G:+3.=&,";H<:F?!$7+-3+4(&=8!-38>-2&%?C"@*F7#.,?&5F-H+.*31AD.$0&<E7;(0.'C/.1;
@r7257
NGCCNGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTGGCTCGTAACTAAACAGG
+
!+"*"+)%!))%'+'"**"&'%!+%&%$"(+'$$$+%&###"%!!!)+')++"'&+)+$*)+%&#*!%'''&!+&!""+#)))%%!+(+#$)+"!$'+%!##"$#+#)
@r7258
NNAANTCNTNGGATCCACGCCGGCCGGTGAGAATTCGGCC
+
$)*(#&&$)$(++"&!)*)'&#+&*)()++$''&%&"")%
@r7259
GNNCTGCTGGAGATCGAATTTCAAAGNTTAGTTTNTTCATGACTTCCCTCTCCCCCAAAT
+
'!#!"++)+!#)("'*++'($&'+"#"'!#''*(%+%$+)$$$!'+'&&'&&"'$#&&&(
@r7260
TNANNANNTCCGTTNTGGNGCTGTCACAGACTAAATAGTTTGAATGATTA
+
%$%'"("'!"(**""%')$$%#$(+%%*&'+$#(%)"($'%#"$*%*&!)
@r7261
GCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCNGCACACGTCCACCNGTGCTGATACCGGCNTAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTC
+
2G3$8.FF!975-.&);&DH>5.F34E:2,"'!'=<#G9#?B(B,!=1'F/1:;H!DD8!9!H(&AC#C9'=6;6667>3#9140(#B48<0BC7113E?2C??87F*C:*$0D<4)3!&)'FHB9F/?2>36!640'07@4%''A-@,?,%D;!$6'<A,B5:;G
@r7262
NTGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTC
+
!25?5H4*@&F.>D6H<9<.;HD$#/,2.>3A8?$*1DCB,<*=!>*C0=9.4$AAA-.&"E9,3,&!>>=46<D#;A/D%0F;4'&3C'E6),C&-8:B3F7
@r7263
CAAATCAACGACCAGATCGCCTACCGGTTCANCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTC
+
*3+-%$4HD,++:7*=4>$,%+-;#8FD&$*A!F22-:0+'3H'G3D&<,8;B8E76.=GH!6./?27G#'
@r7264
CAACGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAA
+
1$F")AB.42E4.D8-"2B4'@871D9==.4/EE$D@'G9.;#3D06EFEE@H-AG&@,@((E//1A?'';H#+F!G;>4.#6#326<)B'@/*
@r7265
AAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCGGCGGATAAAACAAAAGCCACCGTGTCGGTC
+
6.C2:E+;GG.F>)#?@';?F/>>;58$-E!5!36#2*3C!144C.!7D#9+=C&,6;2'"=)2.?=;?34*G=:-8387EC;BA)38:2,B?*&/C8&:6)8@$AC'#7%3F)FD2@0H=FEH&/'@#9077HH'EA'E1G+#EG32'8%!,'7#B$.D;G+AF9-!-"
@r7266
AAGTAATATTNTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATG
+
:??=#D:)(.))'$--(+3DE$'#)!.1H,&H6:4,D;4%/&09$$F(,25.64G?%"F&$,74"/B&'!!6;4
@r7267
TTTGTGGTAATAGGCCAGTCAACCAGCAGGATNCGTGTAGGCGAATTTGCGGAGCTATNAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTTGTCAGACGAAGCGAGACTGGCTCTGCAGTGGAAAGCGANATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTC
+
:+-H+EH/C4,F+68#5)4/H?)C247042#%F4F'3.=H=9$!&H$G#F0$=HG,,G$:3?-68'!<$H&.;B9"":"17*.E+6"G-."$&A$CF6*(2(877H-5%B$5<&=%74@,)3.+2G.5/669%=D(.FH/=,/$+;@#%3#B2/<*-%HH+,.%?3=&"=HA1,5A#)-:#
@r7268
AGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCGTCAACTACAC
+
.3/E78*63=9:HE7B*(/,-G=B5@;"?.$1F0(5,%8(6@?76(/'A=ACHD*H/@"H-3:H(*==)1-,*02""&=8G<=9<8:"4&-7";6$*--0<(F58)G7G3
@r7269
ACGCCGTTCCCGNCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTTCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGNTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTT
+
":)).5E)(#22/-/'E"2&A437C1C4*3>?:$6('7+/+#7"F14F319,=9'ECCB>*CB6EB%HH!5#4+F.CF"A/%;<06EF)'3G:3..=!:*>59;>$%@55:E5A9"7H=#><%8*=+&8<>"739978>*E9?0D;B@>8(;$D,H)C+H),/91=%8/#44.F+F*#$EA*"H:%<3!HA980=A$,.7AD9>;6$'&1>1@C(/2,=C)@,.C%:"2AA@@5!=@#-/<8%>7%;-2>%>G$!%,+
@r7270
GCGGTGCCANTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGNCGCCCCATCTCACGCGCCAGCTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGTCCAGGTGGTAAGCACTTCCTGCTCAATCTNTTCAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAAT
+
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
@r7271
TACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTG
+
4F8;C&A4<)4'<58)%G.;72D3E&*F383;F7!?,H>3$<BG<A%%;$%'G'493EE4:1+):",&9E<A-(G/8;9'%*/%C:7.?H$585%-8
@r7272
CTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGNTGATTTGTCAAACGCCTGCCCCTACATCAGNACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACATTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACNGCGGCGACGGCGANCTGCTGCACCATATTNCTGGACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGNGACGCACACACTCCCTCTGGCGTCACC
+
26("7H=.D(8D3D&"7A"BC"%;G>$?))/:B.+CEGG=$-32@7/B=0=)/ACF)+-)*1,-C9C;E-";8G7'D-#F91B%A'#.(/-773,3H55%$'.@-**+,26+A@;0G+"6B?@:*0(:&*)-A>$2$DDC;7(43&59#><1'+3F?>:D,)+:&73?'"EH-,"5%F'":%H-=8D$H*B#B8<FF%><AC,&E4'*"?.<C7"'9,F;C$":C%9:9")FH((A%-H#-;(EA)@G?GF8#9A9+'("D,$4"G857"DA.-<0&8*#*13?-8CA?+7971E
@r7273
AAGTTCTATGACTCAATTGTTCATAGTNTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTNTTCGTCATGTTTTGAGTCTGCTGTT
+
:71H:#<D%*3?#$'>B4,$*4!%G-')<A3;33E&C17>8B?3,B>G$&8(%/A960=<+$$%/#B"+G&7/?+3&CE2+5)91!=9'9%(("A).G20:35
@r7274
CCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTNACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCNCCAGTGCAGTGCTT
+
6@DD;C-F#C6D'A9.8&=E3.9H$4?#C(>;2;&"((>D0"/.FG94G03-63;7';D34)$8(<)D,)*8$/+>H!"B'-&23>8F'?,1C*:"-:1,F44F
@r7275
NNGGATNNATGAAANNNGGCAGACATCATTGATTCAGCATCAGAAATANAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCG
+
##&)*""#"#$&**!$%('(&)#+)#*!)'+&")!+!$!#+(*#!)+!%)%!$*&#&+##$&#&$+&%()$&#&$&"+&)"++*%#*'%'*#"!$!%!+$*#!(*##$%%#*+!+'))+"!"!""$*+(+&$'*'+)&+*)!"'+$+*$+"'"&(*&!(!!&!"("'#+$#)$&$$(''#$(*)!'#)+*)!""+!$%!+&*#()'!)'*(!)#*+!&)$"++&#%!")"#+
@r7276
CGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTNCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAAACAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCAC
+
-C5"<H+F):G)!-625,E'G<*6!$5F&@*0@B"AA2+)1(08D+%>C?C6>E!!@9#..0=?")$86-:.<#E8);':>$>,:B3(/B*9'@$-=:B8'0?73*"6B6,?5*H45%:C+4:70F0(@23$#.40!7:+01(,58"&;#1EEDFGA/$+B,6=?/F;
@r7277
GATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACTGCGGTGCGGCGCTGGGATATTNCGTCAGCAAGGACGGGTATCCTGGC
+
E@8%:">G$*'A/934-99-/553:5!EF1$02+892H6B+*A+B?<$H'B94!5/D$;C"%'5>-7*G01=!,G,?4D&!>4#9%F#+CB068@'#4,$H.1.:/1!2")B=#F:(&7G$);F#.?69G
@r7278
GTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACG
+
F=/8F75@345<.($/":?@0*C?'>)>#6)1">8!"G0$!5!(*#H
@r7279
CTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATTAACGGTACGCTGAGGGCGGAAAAAATCGTCG
+
6*0>"B6#-:CE%%&"0>")"H36:=;9'4!*DB$/D2;B>@7+2+%>"6E&###@,HD0;78??&7H'$0<,!DB.
@r7280
GTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGT
+
4)&CC*2$;1:-AF5(,+;C<30149.F0$9C9#/:3',2*89B3H",D/':C6/!A=96HE
@r7281
GTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGG
+
30?2&F=/-$0C.+@&*5;:,2(58F/;%>=E:(9(@(9&=1"*<5:.2=HH?*-62*);-#D-H@?C0G(6@C89"5F(<G/44#"-<$/.<>G/E(3$@+@9C$D4+-</%..!33-6/GG="8,":%/G!+6&<8"#C:D3#A+.
@r7282
AAAGTTGGGGACNAAGANACNNAGTGTNGNCTCAAATGGACGCCGGATGACCCCTCCAGCGNGTTTTATCTCTGCGAGCATAATGCCTGCG
+
*'%&)*$'#))'%(()&*''"%!#"$*'+*$*&(&#(#!+"'$#(+!**&()%'%)($(&$')!)*%((#(%+)$#$("!&#*#!%++!'(
@r7283
ATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTG
+
H0F:!$D9&A@3&@7,'>).;'#8E".4=*C&/C:$,;":F-B?#G="-<58:$0%A;A3E40"6',$@
@r7284
CCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCG
+
!<'+:6*#6-DA2DF!#:,6@B9A4=8#F2'FA/21%H%<9%EB(/6?,.>GA=
@r7285
CGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCCTAGCCACTGTC
+
/GBH1A:EB>$6E?$8);9C;4@'&=H=#=-',A+$..75HH*,'4*9?0133#%AD(&/CC#..13.E80$H$:(?C!4:&8":7H*?>0BH
@r7286
CGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAG
+
!H=8%9HD%D)@)#.6:C71F)5"CG84'5/;F@HA93(>%2A0.71825!
@r7287
ACGTTATTTTTTCTGTAANGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATCGTCA
+
@$;.>#?'&9'<;H"7)/+*!;<A,C8362//H@B38'"-C<-E+<%3D'9306@#H1>C1<@0:6<%"6E,?F84'574>%&A+0EA*B0C**8"7G.()+!=66$37*=)#<<=?A!%("-E46.E0A+2BA<0:#11"$:45F.:B;-<3H:@%-?1.E)%
@r7288
CCATCAAACGCCGCGACCAGGAGAACGAGGATATTNCGCTAACAGTAGGGAAACTGCGTGTTNAGCTTGAAANAGCAAAATCAAAACTNAACGA
+
"#*,F/D8%BF.+&3;."H9.D>'G:9,3,30@83+A#(@.=G(<;C"=D,0&FH)=/$*@5>;%?D99"&54%+,%<8D(?AA;3!933=HFF
@r7289
AACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGG
+
&G4.&1.0(+&6=>F22#<E;-91*.7?F"1(2675+)#G7"EH0D39"C7CD3A061F//ABF5
@r7290
ATTGCCTCTCGGAATGCATCGCTCAGTGNTGATCTGATTAACTTNGCTGACGCCGCCTTGCCCTCGTCTATGTATCCNTTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTT
+
&'(+""$#"&"%&#+*!%"+&&('"&)*+"%$$!#"+'$)!%&)%)!#(++*'++&%&'*&#*+%(%#&)(*'"!#+%!$"#"%$)*)'(''!%)*!'($+*(&!&)&))&!'(#*)(&*&##"%(**$*)+!""%)%%'*+)*$*$$%&&)
@r7291
GNTATAAAAGTACTAATCATGGCCCGGTTTGATATGCTGATACTGGCGGCTATCCAATACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCTGTGCGGCAATCNGGAACGATACCGACG
+
%!2:/F:7?)FA&)(#H,=$%)/CE.3/,,"?448;@(0,F)#A7C,@&'40%A??A$9C/B>!=C?;)HE3%44C00%")'/FB-#<1/EFCH<B!,77+B>2)CD#/FF5D@DD9#$6@>&4/=9'0,!2E"&)!E;H1%?D(E*/%9C<.G<""A=!$-G236;=-&@04*+E8!!;:1@5,0H"9F50D>H$+F84.9E=*,=7GCF)-'@.7FDB'0@"6.>*(-'#H9'G?7@,$+-&#3--!->,,D1&
@r7292
TCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACA
+
)9@>2.4CDH6/0D58C.:FB-B?9&$657A),D9GC@=7,,>;F$;(>"93>85:/C)"<0;7H?A4@!;G++.G1),4#4;A+73C:C.)E:/8;-"49B%6"67F1AD#'+>5$HG/0D7!.:5"3--69<.4%)/0F7F;E-D-9'$4HF(1);#
@r7293
TGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTCAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCT
+
;3$AD(<.0($;-4*,G&,4+B$7"02A=G244A/(A115D.%=F<1G&F60%>HE@35*'$3'&;$G.6@444$(7*C%;<#$%H@#27#D3!<B&:D/8.<$%G3/G3%2%?6#,@;1B3@=6+>5E)0"#*B>8;@F,4>.3$=-G$?$?A9$63!-B0+$@(='<DB%&9F"#&%!G.@!>!$;7#$!(7F3?2,/83@$9EB70A?C!754E=;'
@r7294
TGANGTTCTCCGCTTCGATAACTCTGTTNAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAAT
+
'.-9&A!A25.!F=F)(@B7E&948246E@F*C/D$G-/0*F2/(7@3B%9HCG2D+H?7F00%7B-"2"6H,)=BC>==?E*)&G")<4!)%84$30B2257'EF7AG+:3
@r7295
CCGNTTNNNNGCGTTGATTTTTTAATNCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGA
+
'($#%)"')#'%(+!)%"&$*(()*)%%#($!"+$(*'))"+)+$!#)$%#)&")$!&$'#++!!"#)!)*!#"$+"$+(#(%"!+!"")('+&(($%(++$'%"#"&*+))(!+$(%!#"("(+("%$&*%
@r7296
GGGCGATTTGGTTGATCGTGCTGNAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTNCGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGNAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATT
+
<6;C28$-"@5)01,HB87!,=0#/6"--EB./*+5D"85/$>@/*E6;)C%$:8825)62*E-?4(D53%.=1C2C=59<D#<@.:/3H0;#%DD(9"!)51C6BHE'0>3.F929(;AB-;$A$;$?&FF,&#F+A'90#H>:&.2F&BB!H=:B:.G4&1/6G2@B7AC'+52
@r7297
CGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGNCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTCACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCA
+
'@>8A>3#9#2G0)07%(=<3*B:"$!>23#;%1A2;2'FHG.,-D=G9$-=H8!':C7'C;?C@!.,?'/=$>,.<>+<,FF'@2>'/'+5C#%FGCGA>:81?&)3-=@#HA@?C7FE&(7!#/A#4>>-;*174'<@7-'-<;0.D%6,@*H,A.C$,.-07E<<'20
@r7298
CCGNGNCCGATGANCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGGGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAAC
+
)'%"'&$(&'%)*#'+!%)$*#(!%)$%!"(%$("$$!!'*#%(%#%$#$*'!#%!%%+)'%%**#$+"'&%)'*++$)#'&"'#%*""($%'&%#(!(&%')++'*!%('&$"#!#$#$("%'+
@r7299
TAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTTAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCNTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCNTGCTGAGGTGTCATTGNACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCC
+
G1C,4A>#@=28;0'($4"?'-7G)&!(38,0+5:,$H+F('EA*A$BH8@#?767=H!'@AH1G":HD-F8%8&C/!#=;F9'>A+F44$+4:9A$H.+1;74D=":!$>E1=.95#:2)FB0!>ED$>>GE"7/;";3$!D:&?D>1F.#,(7(A0?G7+:?C889841FA#B!;$;6DH19B7.;C%4<$=H/B63)#;F%,,/<H5803)96G08+@G9D16!=D*2:7?5G5'H,;3!@=HEF@5H3+!;A9E?/>*F%=@0F(4=6G(,<:%$-!39GC-*,HH(G(-.CAD.!H,05+!-"
@r7300
CGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATCACCGGTTACAACGGCATNATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGG
+
5C<&)$!+7-D=5))*8D"/*9<+G:&%1G(%A*3CF?+A&F=H*+$*>)1@5EG513D?$B8:DH=;-"7/F0D+.H+;%(0D?%)-8A2<?")$4%'A0'8AA*!8F,<(''?.:>'>A>H=('G9C.91F3@5,:".,H;%D+"0
@r7301
CTNGCGCTGANTAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGA
+
;*9'EDG.$?)0!A#%C>138/:=0,21F/"C&?CE8?"4*4,3"E@<??58@+#)19,>=!A-"*.?:@G*0CB"@#H=-2.3";0+1,40?+8.B3:$2
@r7302
GATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGT
+
B-'2-*+37;'18A9,FE?G:>-@@.!""C)-&GB6!.2%$)$;&?A"">6,%H8G:-$9G3&@,<0%""3H1@B..
@r7303
GAAAGGGTGACAGGAATCCGTNGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGNTGGGTGACGGAAAAAGACATCACCACTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGNGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGNTGCGCAGGATGACGCCGGACAGCAACACAGACCAGCNGCAGANCAAAACGCTTTGGTCNTCATA
+
(0$'./!728#&GG83-+>:F/<#)+'?2H>EF+''58129+8+F:+)$HC:%:62!0$;>(3$@?.:./3EG',"@)<@HE((4"H$?F;,7,53D;EB'6A9(EFBG/E;;CA$<6/&79/D0GAE&.$(:-H76F"DB3C930%4*@*,A)9C-&;6F/58/58B?H>'2%>!C"+?B&H(@4%01>?HD>3>8/D!A,&B'*?(B);A/-G&$=3:-/@>@9G2E
@r7304
AATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCNAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAAT
+
41-E?E"<C;;F1&E6?@+%1;.D4(-:!F%BA!1H!#%0C='$12"=.4@<007.0&<)$(():6C.B)57(<20.=69:
@r7305
CGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGG
+
E6$!0!-$-/*@:D,'(G<E1E8CA614?==()'<AB68-0@F.FG7#%BC:<*&<F#.)B$-,+
@r7306
ACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGCCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATT
+
9B)B0<?(2'F;E?,(=///6'2$F"C<G#C<+316'.):6&2<4/;4>:0B1)(767!5"A9%*/4E(&6H37$*#'-CC6BE,82%6C/6/A;(6<?;=BA5A4BD
@r7307
GAACAACGGTGAAGGTAGAAGCCAAGCTACCTNTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAANA
+
4$10,2C&<@<94?:%'$,$:$@H&&>C1*@&>AB.."1("$9*4DE%&E:E)/?C/:,58&%>)F"*C&316B(4H=,:FC,($#><G(8?C$,B#1'4,H(562#F#,<%/=*FH"EB7/0(3/2<C:6?%28E(-
@r7308
CAAATAAAAACATCTCAGAATGGTGCATNCCTCAAACGAG
+
@=F-/A:9$"%B3//7-9(-&?:A07-("A!!9G9E<4+(
@r7309
CTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACAC
+
@4.G@0'E.@F.@:G%0A="42.#;:",E>):1*:9>.7$6A:3*G"/G7H-54HG!C'#=0B78!15E*1#9=(#$*%BH65/G("8003GG'>B4649$H*(.;,+&/'!@+#&"E)<@G8""8EB>:%&FHD4,7'@"B=G'*&!?%*?9&GCG,?;""48)+!7!67,$$#@.;
@r7310
TCATTCAACANCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTAT
+
4GD-0<D9BH-<3-2C.B"&%1)337$?'2;/,!'1A(?F$+19C).D5.6F'/B)@"/-D'1%4<4E):&0@3F("$:B<1C9E)H=&"
@r7311
NGGNNGNCANCATTCCCGGCATTTATCGTTTTTACATCGTCTTCGCGCTGGTT
+
&%$"!(!#&!)*+'!&(*)+##!#%#)&)%#*+&&)*&"("($$+((++()+"
@r7312
AATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTGCACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATACCCGGCAAGGTTNGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACA
+
@4>"!H:#<B:H83==':184%F"0%8G-;"7EA,=F)<7842.=7-G%DF0:9""8#HC2%FB<<):98?@B6;1D;"G"<,3,/></?*#=:C;*>G%4,AH0"F,A:..BD.1$=('%8(69-,",F>*.,7
@r7313
GAATGAGCTCTGGACATGCAATTGTTTTATTTANTATCACAAGATTAGTAGATGTCGTTGNCGAA
+
7#;*5GD0)&$$%H4=:;)3+CG;?!2;H>'F8;=--;*5<@2!'0,+/:*A.2!=/35!-"5@B
@r7314
GAAATCGGACAGGGTTAAGTTGCCCTGATACCAGGCATACGCCAG
+
:B>739":A91G?*(1C$/5%,1,F>H3B8;,H0#)<D.-@8=;7
@r7315
TGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCNTTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTC
+
8+3(@E:?3D:48G17!03@11?:4,4C7.1A-.3(++8B"#C/2''+#!<&D!@0?."E51,DA!,$1(<100*-A@@B=0:9B88G:AB(5(*20&58F:F@@D3;"&978DD
@r7316
CGCCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCA
+
:D!8$D.0!97*&&0/.>D>:,$2%;:+A+1E)(-*&HA,F3%=/'#=-?/8-?0@,/)C$%.@7@.<='*
@r7317
TACAGNACNNNCGGNGCCTCACGNNGGANANANNNNNTCNCGCNNTNNGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAACAGCCATCACCAAAGCGNACCTTTCTTACAGAAGGGACCGAAGCCACATCCA
+
&!'()(()"#%!#&'$)$$'$(($'***!*!)$)#'!&(%#!'$(%"!&++'"+(#*&+!$&'('%+&)%+#))%(#!"")!'#%"#%*!%)&)&*)(&&"!!!$*!)%&)+"*#+&%&*($*$)'!$#+%!$&%!)'''&%
@r7318
NTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACNGGATGCCGGTCATACCACCGGCCCCAATGGCNGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCNCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTA
+
!;2(19,=%397FE!=&4%'.H42;0D:4HA0'F:&!D@411AE4?+0.)7"9C.E:F4144&%<&*88F4GD;G;9;#4*"=BE034.(?B7>?>436>%D+,%#E(;$!53(8,72%6+:>H/-2?@'&'$@'73+:#-&/7?G?.4E5+#F&8+'$?,GH'-H,0H5*,02>B!1B1'@6";8/*0:*A.H*?B>5)<-0AA,%>G;1<&<!5.0'$:)
@r7319
AATGCAATCCCCAAACAGTTCGCAGGTAGTAGTTAGAGCCTGCATAACGGTTTCGGGATTNTTTATATCTGCACAACAGGTAAGAGCATNGAGTCGATAATCGNNAAGAGTCGGCGAGCTTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAA
+
6.:5<(00&;-!)%8D:)//D+F=7/4$(87?65D:<"F!7E?&>78A?H%,$D&E!?",$B$FA2D2('E';2$-*(9-=4-&2H!3-26.7;@)18-2BFH4>D,FA#@)DH.3/#@E<@$48A5(4##&E8*0+9!3$#@#-*D@8@D(A)2"EHDD$
@r7320
GGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGA
+
&24(7*/!'>0H>-A(%$'D>.3H18H2-/.B"H=&5=6041=7+CH=,CE9?#95B:%E*75#$7H5D9!+B73&%G6)'0<:%#/77'2<4'2+6:/$
@r7321
AGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGG
+
15'+017=7C75;FC:01*@#H4F#6@/.BBB9C(-054>
@r7322
TCACNGNNNNNCTTACNGNNNNNNNCCNCCCGNNNNGCNAGTGCNNTTNTNTAACNNGNNANATNNNNTNANGTTCANGCANNTNNNCANCGNTNANCGNGGTGGAANTTTNNTNNNTNNGGNCNNACGNNGGTGNCGCCNNAAGTNNNNCNATNNCCNNNAGCNNCNANCGGTANATNAAGNNCNGNACTTTNCAAAGNCANANANNNNGAGNAACNCTCNANCNNNANTNANGNTANCCGTGGTCGNTTNTNNGATAGGCGNCNNNANANGTACNNNN
+
"$"$$$$!$!#"#"$""$!"!!!$"!$!#$#!!"#"#$!#""##""$#$#!$$$$#"""##$#$$""!$!"!##$"$$##!"#"#!#"$"$"!#!$!#"!##$$"$#!$!#$"!#!"#!!$"#"!"#$!!!$$#$#"$$$"!$###""#!$!#""!##$$"##"!"!"$"$$$"!!##"#!##!!!$"$"#$#"!!"$"!###""$!$#""#!!""#!"!""$#"!$!#!!""#""$!#"$!!$##!"!!$#$#""$$#$#"!"$#!!##"!$"$$"!"#
@r7323
NAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTG
+
"H-4D.@$%#A?-E19.D1.#CB3@F!+1:!#-8<!C88"@",>:>.<)(6<=)6,
@r7324
CATACAGCCCCGTCGCCTNCAGATTATCCAGATAGAGATTGTGGCCGTT
+
#?H'*C<;6!,FD57:,$+:!9&'G4?G<2A!(!3E-<8596G4</;<A
@r7325
GAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTNAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGNCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGA
+
59*3F3A2B>/)&>C-%,9!":/.&8*#0-&F!F&&/C=)("1,!E9%H"()7%8;8'A/B%8))#0"/-<(&D=27@/&$0.41.C=,=:"8.*4'(=?."8)H$-8'/@=A1AB@@732G0*DB1!8)$6)7:D;7
@r7326
ACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGNGCAGAAATTTAAGTTT
+
?4H.91#AB%?4GE9,#HC1G#=8,8+G'*($D2.&&H61,"C<;B+!B(C"%3D.F8=;@@%,+G6:(?
@r7327
GATCACCGGAAAGGACCCGTAAAGTGATAATTATTNTCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGC
+
@$*"+C;3$%$"$&FB:3/*0+F58,#+=*.<+2#05D@4?+=F=(?7#G%><B(>%*-H>6616?,B!$1%:3#;GG/90(-4#*=!9:6.4*C;8=<3<3%#C11<@G/32/3DDDD&$'
@r7328
GACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATGAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATNTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGT
+
2+(*9C$7%;>:G5;=;.1HG<H,C$*&*>"A0695/;3F.8C'#G0=!9=B6%+0HC8(F!B$G)D=65.,;F@A%;(4,3BE=B7'140;665!H094C137=9-,:42*1-D(BE@/&39CD':C@*.!?D&;-44,@"4F=-/C:>E0"F,AD5=&+%'*%'-FH+G9"6+H2/+8>9-,>#;ADG-G11<!5$<!A/6<,A6.G*9(.25$:<=(#@0>F)F>D@?:3;()=HDG$:/92(FDD!)G54(:CA?>?*FD3'$/$/&3G/E9@")E3:77$/'43>"*A95=D/0C;!6.-/835A,9&-A90*?
@r7329
CTNAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGA
+
$#"'+!%*)!&$$'#'#$)&&)#%%*!'$"&*#$"!')#$!*$""#($)&*%#!#"!+('!$"&'#(*#+!+"($%&'""$*!&(#*##$*""+'
@r7330
GTTTCTGTGCTGNCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGC
+
2&+E3@):!HC/;'F*9-0&690?#172&-4>-A44++#)BD*5('0H54?(1/3C)/3:H81@;AD;&H"4;#&#.#A;;BC%9*%4??;-H-#!&DC1CA<BG5:?8=%"-@G?&//&5$&++4),><:&<B
@r7331
TTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGGGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCA
+
0/=23<D;$&E"%5DD=!!22.G;B!=/B85)43C$@;+EC6%@=!G73?*./*B/#/7GA2"F==#&%(,>3(1F;+D#H>*5D.9;A
@r7332
NTGGCANACNTTATNTNGCGGGTATTGGCCTCTGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCG
+
*!%%*&!('&)"$$")(+'#$'$)!&*(!*(!'#((!)(&$*+&'%$"$+&!'(!$"++$)*'##%%#+&$%#!+"&*#)!
@r7333
GGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATG
+
9D7!)*4!(F%.FC8"=-H7$:@+*>4."<$8>,(0@!621D9':#G
@r7334
ACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAA
+
2:$549*'&8?C1@&A=;40B(5G'9)*9C-ACE?*"H-EE8%7?0!AD:.!;3:4($H+#=#B4$!H/)0+>,?A/#7?;#/:@)9H/
@r7335
CACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTG
+
1DG(%H1*#=636:?</E*34G>!@4AB*;*8@9!#CFC'G6!;-H;,?/03#/@3)AHGB.,#("17)B1E(:/+"<7#872?C!)B
@r7336
GTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGAT
+
C$4.A3";4-:';G9<*"-@3,'AE+#G&-$9#>7.7A&F)++;865@3?,3%)%+(!9"A&?4-4BA#0-.+<)<3?478DAE%
@r7337
AATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCNATNTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCNAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGC
+
4H2(2E!-8H"$2:A+(>+?D17;;0)!.=;>G31.+5H&##*G$%=?+3,>(.:HE3D0$:B+@780$<.84#-9E@&D=4!B7%)G7!0<#)@!-9AG,!@>94(57;)>9-3$3<).DB).A>5A"1G4&B#B*;.0:GG!(>*?>H7;".G#@"#/2A,)$*!'E>2G9.4*8%?C>C0:A)@HH=!,"54-BA!4B?3G*9"3'72/0(-3A4=8<B0FF%(5=3
@r7338
AGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCA
+
7*:2+:"#;",.B9.D0)C#9G?%)5<8=E!4!=AA'5,!@3*7(#D3*G8:4:C#H405.
@r7339
ATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTTGCTAACCAGGCTCG
+
&6@=-,G3%$9C0#88<=0*(,?G#3);(85C+9?F8;#;.<*=7A-$+@D5?67E&H/9=#%/1/&
@r7340
AGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTT
+
84G6.(-?=/;:,F>,=@(#H79'>D";&+!%%&?"G?8AG
@r7341
NTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAAC
+
&,9&H'3GF(2950$4C$6(E0E+=6'@*-"CA223&/,4&>5,G9A8":=+44B'3B9%!H=4D@<
@r7342
CGCTAGATGANGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTAATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCC
+
)3&/,#<<E2?4/!#;?5C"(D0:3$9C>0*(AC(,:42:7H*"71$;"&4@@8GB%!2'='5?*;(.?@&%%%'@2;0*/'1H(==4G/;)<<B8;=1>=D5C,%9)2)51%88G-?="E%0
@r7343
GNACCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGC
+
&&!)+&%'*))$)%'#&"&!#(!$&"&&$#)$*!*(#'!$*"&+'+"(
@r7344
CGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGA
+
&47A5718,@9/7=7D+E!4/D.)%E@7HHG:?4.GE>#)>8(:#&.$&-A,(4CA(.38;>&9;D9'8"//%GD4=1.77
@r7345
CTGCATTANAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATG
+
%@;(0FB31>7'#E".4,F(A'!(:9)7"#9;8&%'.=$=99#E)"E
@r7346
GTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGACAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTNAGCCGGAAAAAAGACCCGACGATATGATCCTGATGGAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCG
+
F.)"H'@@D:1=",F&;$>4*;:.->1C*4&*@D)+$E#&9#<%64<4>1/E<#1#1$B>)H,<=B;>=D3)8;;>!.24)#&2-HE&";&77BG.2076F6:G>>"/E((2&7C=A&$@G-0!9?97B,:5?63A'E2G1E?*>-+2";0>?/#%'"$2$CE(;?-7B0#.E?
@r7347
CTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCNTCGTCACGCATGTTCTGCATGATGATGCGACNGCGGCGGTAAGCCGGGTCCGCCAGATTCTG
+
3GC(79=H-8'@:A64"0&?%)9#FA&E9,3+**G@G'DAH(0"D)*D<!<4%GEC4;'?=*$30!.=/#EF#*1C<)?%07-'82**4=4/DB191?("4/,6?>4,*$+H"3.%&
@r7348
ACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATG
+
=+0A0D*+5(@:*."(-6:0H9F$4?5B+(#?-?D#@DA4:!
@r7349
AATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCAATTATTCATTAATAGATAAAAA
+
+#!&*%)$)(*')'#*"$*$(%"'!!#"#*$"&$$'$&)%!#+)&$'++!!&'%!*(
@r7350
CCTCTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAA
+
C9%8G-1,&0"9-5444G)%!/"3E6;)=&/.H-5:8,,"#-/>9/(*F=-?C37;,?!;8-0,(-:3=49"H@=>H*-D/3D!*(;%C<F*930C*!78(0C(+9C!0=
@r7351
NGTATTTTATGCGCGCACGAAAAGCANCAGGTCTTTCCTTCGNAGGGGATCCG
+
$7B?>=':>4B<&%"'%/5/(79329$3#?D/?!;+1:(19)&*32&B6&'F7
@r7352
AACCGCTNGGAGNGNGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCA
+
%*#"(*$!"&'()#%(+&**!#%#'$)"&)++(#!!&"'*!('$)%&!'*&*'#&%!&%#"$$!%")")($*%'(#!!*!*+!!%)#(
@r7353
ACGTTGAGTATTTTTGCTGTANTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATNTGTTCAGAACGCTCGGTTGCC
+
&'7=>"$%F#4(F:65,&"!&"2@3+1D>DDF?;0D:!?C*'=24,7,(>(@<35.G:##$*)<0@*'('""3>/B):/,)>4F20&D>&<<4+5@%&AA:
@r7354
CTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTNATCTGCATCCACCTTTGCTCTCTGCTTTTTTACNAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGNCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTA
+
BA!&"6H7G+?3,$E(=%CDBF2>7<?,/E5?>).@(2AFA2:D3>'6/B/-.5EH377;*,&<2>)A*?+-/;E<@4'&CB5+:@<3&&E0?E<G.!#(-(A'=F8.2-FA'G*C@%7/;+2?BHE>+?.*.-.%CD;0608*(%+20+.H%9$H>H)'-3#5@+5B,<<55)GH!+/"%E/H:B?(30D,-+A;,59<+"*$+55H$;H4&;2#58%*?8@>&)+'@A?:$$4G1@#H3CD#:%=G*G7(:8-<>5C;<%6*%D;F%>E;CCE2.:%@"B?/D?:3=1$+?7+A<+93-'83C+F="H4B"=#(B7,3C%A9<?09C$.E,?'&"7E0*C17D'2=&#'C+!687@
@r7355
CCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGA
+
?+GE/4#$3B*659%.*01F)>/B;.$,C2#B$?3B(0/.)#('.%7C#3;6
@r7356
ATCAGCATCTAGCATGCAACCTATGAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGNTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATATGATAG
+
2*;"-'..<H=2G?1%4/CBFCDD)349)F1)C/"/&&%;;G6$H"..&*<+)5B&'&?+5CC:;CF3*-1+/:"H:5:GA225$A=4('6=B=-:;4./<HH4?4.7<8"(F2@<$HAA#<)A;#3)H.!@&D?/185H)@9")0@AE7D>-@1&29+%AAH00#G<3)?E@/(?!5+/8)#D:A4E.,B"3D4,=DA1:93-*B$H;!F)5F:'F<H.8<,+,7A?+8>+74&<-3@;B59DE$6#E;,6B1)G%3=&,@G4.1"A.@A%3D+/1>6BG=+%%!*F3!4=5?;F5(8
@r7357
AAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGC
+
C%C:1A&+:%0A9D@3$#8D/%5+E8%3&2G<F$B"2'/4**DHC)0DH)>F7.=5>>1&=&E-#6C+B$5D0+A
@r7358
GACNCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACCGNCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGNACCGCTGATGCTGCTGGTG
+
+4A3B%E@GG-BH-1!4#%5;@:>H;F&'9D#?/21?F@C'HA@,42%7#&*CBH+&A@:B!#"-==?!F*F9:D+-=$C,=)&.,F;7?3&9(65D:6B+E<*H=*F/
@r7359
TTCGCGGAAGTAAGNGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTANCT
+
#(&*(+*+"%%&%")+!""!&")$#"!!)"%"('+!$*#!**$"#%)%$%&$&+*
@r7360
CATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCG
+
B9>G)!=3<38415E&;6?=<6,*824+86BD:A$-,6G.C8::,2*>B
@r7361
GCGTATAAGAAAGCAGAAGACATCTGGAATCTGNGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCA
+
,8@-):2B!;@/G6'*D?E(CG-:%E1)>,'C(7?(F)%649?G?H&>*A!B)CH/@'.:;;)>7C1,92&>?%2<6*F(-A((?(1!E6=6.?5&)#C992B!<'409''.%5@=*$*<8=C-=96DF?!$%AA,<:2>/65D4*8/)1%>.0.<2;./(96/
@r7362
CGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTAATACCGTTT
+
"C%#GB#52.?(>B$1F?:*1$@.')C?GE(?5.4;-).;95%+C.##6$937.!3@*H(BF8.#,"#'A#2C@6A0H8@F<7"-A<5=H6%2B'<!.+)CEFE2'();+@)<%08G>0,,EH7
@r7363
ATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGA
+
#G8A45BH53=GE!;;3'-"DG0$>B(*'4?'1A/,HE%!7+/.+B5FH*!*$'*<D=@B&F/
@r7364
ACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGGGCCAACACCTGCACCTGGACCTATCGCNGTGACGACTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATA
+
>1)0>D)$2#8D%E/59=1-3-(*GCD9##."C;A$?*>B4A1'56D'7>)34"4-=/72B8,<9-$$C9=$-8*8<A",:3B6"A9H$+A%)=D@:D*H47,;.8C((*-@7'94-,D?8&>!F1=D,%)<6D+79('(+1!2@"H4HC/6-F=E->,?"7>,/#56*5C2DD(%1%*'D9$2?34<>AA@-D,D##:(;<9:@2'137?GA#@'403(">"G!@*
@r7365
AATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCA
+
6G1E$GG.?(H.>H(,&34-6H+5(5-"#!)=@37/:6.>0EE(6AG$7:A-F>E0D)./8.$.--
@r7366
AGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTANCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCNAACCA
+
C9-"<9@-6AE>.D"&)'%#*/1-2(9<,#A,($2,"@@5*+H!5C4B.44(BF#.#?(.:'GAG/B=&(#@;%/GDBA>F=!:C<258E0".AE5-921,809'1HBD8/$@%,F%=D;B&0DH.E6"8H;B(C52*%$1B-;0GE<G5F<BB)3:,2G2'>!!9<4>;5:C+#C?AB!=,*<:$+16A:-.4H>*D%018
@r7367
CAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAA
+
7'!EF2A5;3)(9H?::;B/,G;C)9G=39!#12=E1C;!=)%2@@0+)(@)@
@r7368
NACANATTGNCTGNATTTTAATAAAATTAAGGGTTACTATATNNTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCNGCAGTAGAAAAAAATAAGGCAT
+
%$**(*!$!%%!!&+)(+*(!))+&'((*&!+(("+(&#"!'')%"!#''!(+))*'(#"$*+)%&+"*!%''"'&(*()*))')$++!!*$&+&&*&$"!$!%
@r7369
TAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTCTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTG
+
36?7E)#!%8?H'$(>9-73>)3)B(3.;C<.:<)$7<F-4<4:+',*3>E1&=)*;4-3+=8EG"?&3.*>0,!*,"H"/0"#?G!1,E/@:$.//@8.6H;@46*:$8(7%H$8+*C<AA>)&"=.58$-$)(9,(H'HE#8E897B"F1$
@r7370
AATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAA
+
*>2;&+!CH2<#'5::4C"E$1($;(38B:E$,38G/H&<%6)>*C#8C/?9(+>H,<1>B?B030C8-BC">3-&B0GC-0"H%GE!AA/!32'-<
@r7371
TCCAGNTTGTCCTGGGGGCTGCCGCCATTGCCGGATNATTCTTTACCNCCGGAGCCACCCTTGCAGCATGGGGGGNAGCCATTGGGGCCGGGGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGGGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTNAGCAGAACACCTATTTCTCCTCACTGGATAANATGGTTGCCCAGGGCAATGTTCNGCCTGTTCTGTACGGGGAAA
+
+F/DD9@#?*#%&;D60''?7:7>G7!D,%.2:A5>.G%+':H?%C1+?@8)A'D.$4>,:4H.8%(A@<'C'"6,+-!*GCA0!%6(BC(+66!/:@<82).+CG2%G0(@/4A.B#3"1$'B5%A=56/$,-%E>>3(!=%3-$&D=3(B8;%)55?@H;F7C-@.;62056<F))C9E#A>;-FG?-(@3;)3F*.1F("+1AC!:-,,A=#66,@.60+C:2!A+<&B39;-BB:/E)H&.G26)7-H;40B#$4"'":HB.+FC.8%37E2D(B
@r7372
GTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGG
+
)3@7;/H2')H(4(1:.@1.B,?.2!&A$#7.=1>5+=)'"42%F9/G)CA#>-.4+!@0B/.//F5;<,2#5
@r7373
TGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTC
+
4!-/5)4>D'?0*E*%$9CEHH5;GC%H8-@G.#?C#&81,6-(--
@r7374
CGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGCTTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGANGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGG
+
@5#+78=//')/%$B4B66>73E8'7%H!$&C(#B%&0+F#928A$0BF883*0G#6G@1AB=/%7))7(,58EH4F!)2A/H!E60:26&>9G3(*"75BA3(868(=$65F3.G4*$H5A%$;&H%)<3,:8@H-)%E><,)</#(16+5!ED>$;3%.DC1(!?F6?C/5FC-:*8D@%%6.15#5
@r7375
GGAGATCAAGACTTACGGCTGACGAATANCTGAAAATTTATCAA
+
*.25C8,,DG&%5;103"3.&1%%4G4?C:+-5"6,/%4/3$2+
@r7376
CCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCATACTNA
+
F'>B2151.'1('F1F?A?E7=,;<0,*4#/<..*>)C7791-D#90"#E*+)/??2/;9A-(
@r7377
CNCACCTGCATCCTGAACCCATTGACCTCCAACCCCGNAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTCCCAGGATNGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTCCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACA
+
5&!C0/'7BH,#&5/?1B##>@649H#,!'5174/4-86/?.!,7F/E%%;+>3=#=H93?B&88!B?4()D,GG2"A-,EFG>$#%A4C#=CDDE+G"C0/D?*@$'09H-$8!8?+H?+*4>/(A;!*(=60;/>7H5"7-0.&+E(3.3-B#%2+8/3>8?70?,"53/#(/G2>57?+@7"!>(=,G'+36>')4<G0A5+@6A()F.6.)88('>*8.@4E)5:B1C0=';B&31?$#:4,2D'(:'A07?@;&)(1)2E)5#E'$31F;+#$(?7?,##@H"!F7;74
@r7378
AACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAA
+
."'.F55:,#/E4#?(;E0HA/-8##+4CD-(3''-+<8A"6892$B58DD;'1;4305G=>$/'%*>,;H'8..1&"G<2C/CE/?!
@r7379
CGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTT
+
8-(D,*:>9.$3/=H@$BB:&'$10#6=18*(%0'F&6.#3''%)77$185.8.1*0;E@(35%?
@r7380
ATCGTATGCGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCC
+
C+=B'"94:AB?69$=:#<$87CH;C@7#;7E+1+G=G%>%%-G***H4D1>?#A&/A"**D6%+E,'/8E5$.#C*GGH-/G(7>9-4:2,52;GA65<*05'?93*/77D>8@<7$#=AG#HF#@-7B?'!H=G41F7E-:=/+;C-E;DH*",3
@r7381
CTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGNCGGGCTGGGTGTCTCGTATGAGCAGCTTTNCCGNAATTACGCCCAGATGAGNTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCNTACTTTATGGGGCG
+
281-&-G-#45!FA,3":<%<.4.#.89&">-((&@!#=*#@.<F?84-&4E</%)A@=B-H3>0<7$.7<A$C3H8&;>$81!&$.1>%G3C.@F/3F"E4:F0G!FF)EB/71&/>1.='%37AD0:B!$'97H88&.>&3.EH6)+3=7!(3,7!=<7<'D(#
@r7382
GTTTCGCTTACGTGGCATGCTGTCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGT
+
H(/GF)2BD+?$F9G?65<=5."7EEG$=4A#61,=&&<#:"%1G2/9#"<<!08">)C(<$:*>G@('.=1!H)916=,-%0").EH83:@BA
@r7383
AAATACCGNCCGGCANTCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGCAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATCGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAAGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTAC
+
$#!'+*('")%&+'$&**&!)"$$')%%"#"%*!!%")$!+&+"#&*#'#)#+'$#$('$$!*)+###$&#'"+*&)!!&%+!!!*$#!&'#'$$""#'&)!"))%&+#"(%+&*)!%!&&)$"%+"$'$*$'*)%#%%'"$!(+*)%"((#'*)'#)"&+#)(*!*)")'++#&&(%%)*)*")*)$$$)!+"+!$*"*%"&&!$"&$%*&%%*!(*
@r7384
TCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGG
+
%ED'5.5#H-*?)"909,=2*25;-'&:(BG4&A$FC#295/(94@@B0<>GF#
@r7385
GTGATGCGGAGAGATGGGTNAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGAGGTTGAAGGTNATTCCATGACCGCACCAACAGGCTCCA
+
,0"E24=EH*+0D##&6F7%E)24+5")8#C(B.A,%!B-+$34>>8&81G06@=&#&H)G8;.+2.9E,D3-&C?;G#D4EFA>5H%99;<#6)@3!G
@r7386
GATATGGTTTACAAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAA
+
2>-$G1"@053*(?$51!(BFA<;C$@'=6G,C%BD'&;1E@A6,E@:89/FD5*$9',.+;"BC2B56CF
@r7387
TTGGGGANGAAAACCACATCGTCGTTTGATTACGGTACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCN
+
B>=>.;1<1B%F,38DA'"/(-A4#724;$!./FE5><(@0G?9-1!$G3!FFF-=!!@<1C1D-*@8*=5-C@E(=,("3?6?#=$*&C"@1):?'G?5.A99$6C!E4*-':B/EH>-("*4>/"(0
@r7388
ACGGTGCGGTGATTTATGATGGCGCGGCGATCGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCC
+
-(,72#:;*!8>FG:0-D*0>7#6>%=B32F56@HC&6<4,B4)C3-,C2+-A7)1+<9+?=DB('B;'0
@r7389
TCATGCCGGCTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTG
+
-)"6E)1E>>/&.,4F+,BF86+89#%:5BG9)3$@F/)1(DH=).B0$.7&$$-C&:BHB+,38
@r7390
GTNGNCNCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATA
+
(%##!%!+++&("!(%%##+*'&()$*#*!#&%("(#*+!+"'#!$')(&%&!'&
@r7391
GGCTGAGCACGGTGTACGTAAGCCCGGAAAAGTGCATATCAAGCAGAACATCATGAAAA
+
4H#A;*F<7*+0A5?FA'/""('$7/GD/5-?F+GB==%;6$$=53>5DF+"CF*58EB
@r7392
CTTGGACCTATAACCGCAATAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCCACAGCN
+
&+++)&"%(""'&)')*%*$$!('(!#$""()(+"+"$**&&!&+(++&+&*%+'*!")('%&
@r7393
CGTGGTGAGTTTGTCCTCACGAAGGACGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGNCACC
+
+3=)FD2F3HH387"5/H5!48B@;/>HCA"37&H#6*:!-=6-#4.A:.G46?&5B?0$AA!)(AF;:><?'6(+G6:<52-H
@r7394
CGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGN
+
+@$.-5-9B<;/@5()#(-@&*#0!6D=;($=C#=3;="!2F4,</A
@r7395
AGGATGCGTGTAGCCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCCGTACAGAGCNTGGCGTTAAGTGGTCAGACGAAGCGAGNCTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATNTCGTTAGTTTCTCCGGTGGCAGGACGACAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAA
+
+A&1F,HG-E"!5.=%'AH0:4.94%"'('5>8!3F"+$:GE4*?#5-2@E3,0(6,@,7AB1:-C"@F'+7!,$<HE+!:=A.71#FHD/9)80%),5<((<<+';57*!0+2D58><1HDD,=($C:">H8&0=22+;(F+1#6)*<H;'(C01H?B<)G:@-/(!:(%0-F=;&#9&*;!(*810!'":/*F52HCC'-<0:F5.=>0&0-/,-<==AB/.8D/FDA4D:5250%4A):$8D-126B/*<E,4.0>
@r7396
TGTGATAACCGTCCTTTAAAANAGTCGTTTCTGCAAGCTTGGCTGTATAGTCNACTAACTCTTCTGTCGAAGTGNTATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATNGTCATATTGTATCATGGTAAAT
+
A!1C8E@7)>B761-46F/0"#9*!?,=6;D:?-C?&$8D7<CHD9E>7@3!2,:.<@"%.FD&$;*>69,73*?C=7/,C-G01'0<DE);"61@HA/A2@*$BB5,'%49$9,?D0*%:1;D-0.H8&@10G:=?"D(7F3.>&(&4?G.=$%H30
@r7397
AATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACNNGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGANGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAAT
+
H6>?>AC$6#B3!81D)01&5E!>&.D,02%*%(4&;'2!#49D-!62F9EE$C$,EA2>,F;#E-;&$1"0?'E-4C4A*D-5$%=C+BG-:!.CCA"0H,#>0&@+7"57)5."(./DG&!73DFB:,>;G/17,3&)B36A=E6/%,)).C1)ADEF,?G8-.#&7G"
@r7398
CCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACA
+
2%8E-58A6.G4F:3%E&/!0/7,-E-C6+/095$81G0(322#"5?0":A&!/85
@r7399
AATGGGTAAAGGAAGCAGTAAGGATACCCCTCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGNGGATGGCTTAAAAAGCGTGCTGCTGAACAGTA
+
H:<F#6,*:-=B:5,)<>1.:6*,'/)'H)31.24HA@26E,3>A%7"==7;'CF;DCBD@0"/A@:!+:,F-:6+C9-5;7&?$,$(D@7>B)**.?&EC;>&:2$B>#9-%@31A7D1(!?6!:F8-=;-$7?,-444*7&+)F
@r7400
GAGTCTGTCCATTGGTTTATNCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGC
+
'%!C")C=5.H41<5E73>1*%E?--+9G4=',(@H77>#::1?<H!2.*&.(G<)B1CE43**++.?")
@r7401
AGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTT
+
9<"E6,-!?:.%#@A2C,"=7;*F"C8.'3+@7*!G4<-&#(&F/6.E!5+,/;7
@r7402
TTTTGTTTGCTTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAANTCATATAAAAA
+
';.CB&,10)D:&0A?2,G+H2:@2#)E(<'+6H@9G2=3)D8<*A"1=73-:2;.F(>B73E.5-=/H&?!G()-D0C317<*'""$?9>H4F>1:;#'F&7"4H:D72-2-9C/(F40C:G"B)*E6;$B<4698$#6"0*&=
@r7403
CCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGANTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATT
+
#<GB%6H8=+D=@FGE%+6.6C!D2A$)CG%#4<3FFG?C5?D-.DC"<@(1F1&&7#47%3E7G8.*EG:#9.'G"8?>?A@E9D;=<@*$76H**)(&H3.0&,2F>3
@r7404
NTGAANAGCAAGCGCATGGAGCGACAAAATGNATAAAGAACAATCTG
+
(21CD;*'$<#-9DF38A=*B7CA8+A#8!,53E2*(A-719,+(3(
@r7405
TGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTT
+
6EC?(,#;E'8.F39@6@8&'7DF4:+8$2A9:F+A$:-9H37$(/><
@r7406
AACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTCATAACAGGAGTCTCCCAGGATGGCGAACAACANGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTNAAGCTCAACNCGGAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCG
+
A+4(-6?%.-B0&2AD0&93<-H@A'<H,$.-*0/D=#=E'6(.36'H$:%2%3C+,%31!E?+F*-.AG%2?"-02-G:&G;GH3*.@)9*##,)CB*<C88F@;)("D)-A!.+;#8G)?=4&DD.2A395A6A"F#E:@;5.*H=7D<BH$*8,$'!$6G<8&F@37$&C1B58$%+74=(>@D"G$2@:$3.%E);D:E-(+<<'%A"G=8::H8C:=E,75=E8?G%B=<44$@%&(0CC55&4.;<F3,7
@r7407
GNACCAGTGANNNCNCNAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGT
+
%#$)"%($'&!&"*')+$'&)+*'&'*!&%)+(%*&"()+%!'"+#%#+$+&#*)*'$!*+'$&&
@r7408
NTNNNTNCCNNNCNCNNNCNNNNNNNNNCNNGNCNCTTCNNNTNTNANATCNNNNCGANCGNTTNCCNNACCTGTNCNNNANTAGGGGNTNNANNN
+
"#$!$$"#!#!$###$$"$#"$$!!##$##$#!$$!!###"$""#"#"!#!$$$!$#"#$$!!$"##!!!$#$$#!$!!$#$"$"#!"$#!#!"""
@r7409
GGTATCTATGACAAGGATGAANCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGAT
+
.9G;9/?9E04)C8C=FBD9E;E:$'E4)?E-1:.($;72?';#<#DB4#=2,5/22%!7CE;85H).*54B;.7,76/1.2>=F$5'$#H)$&0F
@r7410
TNTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGC
+
0&F+7,;?;G%DC>A+,H/2=#:G?DE,87-$;,2:'(@)+-/+,&7
@r7411
CCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTNCGTGCGGTG
+
25B(-A$&8-1-A'G"'!EA4,7G0A.+@G2,)D%=&8:30$45
@r7412
GTGAGCGTGTTATCCCGGTGCNTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCNGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAANAACCGACACGGGCAGACTTCACCACATTC
+
+*'*($!*&$%(*)!+'+%+$&+%#%"$#+"!+$*%&)")*%)*(&+*"+&!"$)&(*+'!!(**&'($!#%"&'%$*'%*%!$)"**$(%)$*''*#()#'"*#!#&&+&*(+%'(''#+((!"#$!*!("&#'*!*))**'"!%"*&)'(%(+)&&##+(()&('%*!+)+$&)(()#'"(*""'"!%&$(!("+#'"%$)!)#))'*(*''%"*$&("%
@r7413
CACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACA
+
5'<>'9'EEA+3!*#:#8>%0:F+>F,38"H!"F413*!(EH<7A#47/'
@r7414
GCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGAC
+
$*,)>#6;*!8+/27+E$H07E;'6!HD>091/4!F.F)/%&H)!B;2*4HH-F282#C<&C&"7475#*>)5$!!0
@r7415
CATGTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTNATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTG
+
,4+3<>6@6H==3$D10BH@#+:C04'%5;169<'82<?6E)-8&/'3F*,80)*/51:3*.FB!%0EG%G9>@!%2H1<>9%%BE+?EB.."+>;?A'.!1?3=8E.FH,8#53;8G?>?>*;27E#8>"9%B)",+#
@r7416
CCTGAAATGTTATTTGCCTTAGGTGAAAGNATTGACTACTATGTTAATCTCAGCAAATTAAGC
+
+<'B(E3D?#/7>40+F:!9<*,@'31?0#5=3F>.>#C;A,,2@"/;8$,D<@)!73?C(D:
@r7417
ACGNATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCNTTGTTCATTCCACGGACAAAAACA
+
+*!+!)%"!+#!)#+$)!(!!#*$$($#&++%$#*%!#+&&*)$#"$"(+(%*(()*)$'+"#!&#%$"%#!%'
@r7418
NGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGAT
+
"G+DB=D8-51*A6">1=G18*6")GC<0-+<A<%(1,>,@0@"+(@6AC5E
@r7419
TCCGGCGTGCTNACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTG
+
9=1(?>(0/=?"'C=!G=/>;:.!<*".(:::)1!3G%.A85'#5>#/.!"@F42-*3C-)E8>3,>52=15A->"4#B'G+
@r7420
NGGNNCCTNANTCACNANGNTANTTCGANTAANNNNGGCNTTNNNANNNGTATNNTNNTNNGNCNNTTTNTNTGTANGNAGNGNTCGACTAATAANGCNGGTNNCGAANNNNGCNNCCCTGGTTNNGTATCNTNAATNANGNGCNNNNTTGGATACCAGAGANNNTNTNNTNATCNNNNNCNCTNCCNGNTNTANNNTNTNCNNNGNTGACATANGGNCCNTCNCNGATCNTNNTNTNT
+
!$!!$$"$!""#$$""#"$"$""$!#!!$###"!$"$!$#"!$$#$"#!$""!!!$!##!!!"""!"###$$#$!!$"###$!"$"!!"#!#!!#!!"$!##"!$$!$$"""$#!!"$$"#!"!#"#!##$$$!!#"!$"$#$!"!!"!$#$"#$#$##"!"""!!!!!"!!$"#""$!$$!##!!""$"!!"#$$""""!""!"$"$$#!$$$"#!"$"!$$"$$"#$"!$!$#!##!
@r7421
TCCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGAC
+
!'$(+"+#$'+"!)(&#+($&!*%"(&)*#'#)("*$%()!'#+'!&
@r7422
AAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAAT
+
3(?$,/+:EGHE*%0+#9!55$.4G46F357D7=DFFBF33
@r7423
TCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGNGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGANTCTG
+
8'A>8:$1D(95!-""52>:*FH@(?>HD+0E35B/&B4#DG!+C$(=F/!(1*G'+#?;((.5""7,5'8,..!=>&:**;2=F"$F'C18
@r7424
GGGGAAATANCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAG
+
*'$&"&(#)%($)(*+*!!%)&&#!"'!!)+"$"#+#+!((!%#%!%$#")(($#+!"!+((!*(#)))'&(**)(*#&**$&)%!(#)$%$++*((&*%+(!&"#$'*%)%$"'!!'(%)*!!)&!#%$+$)'"(+!!#
@r7425
NATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATA
+
"%?-%4B%'=D$9.78E2DG<>1G45-0=3FE/"8$/>+8.:A&(@/,>'+C'(%?,CE
@r7426
GCAGTNNANNNNNGTTGATCATCTTGCGGNGNTTNANATGCCGGACTTTCATCGTGAGGATGACTG
+
"&#"%!$%)""*"'!'((%($'()(*"((!'$&('*!"++"$$!&%(+$))!$)#$**+$""'$(#
@r7427
ATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAG
+
-!3+1*5@G"G:G9)=E<5$HAA?"*#344EC"+F1+A'F(9E15E/6%8-<.8;DF=B@58?.H
@r7428
TTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTCCCCGCATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAA
+
45F!*(D8580??-4<"00(935)$E"A*=D+3@9)H?C&>A911!E!@!23H5@.)D,-&@@$'3(8C.C*=8.8H3@9@D.-A$,,4%C#0A%E$9H%94#4#"H@*2H/-8!#,#++95#
@r7429
GCGGCATGTTCNGACCAAATAAAAACATCTCAGAATNGTGCATCCCTCAAACGAGGGAAAATCCCCTAAAACGACGTTTA
+
D?)1B@$D$+!,+3*$<4%&<>&C</9#(E5$E$<%"$'B8,$1!2F6@G07D-7-B4D#26#E-19D/>EHD+D>(!19
@r7430
TTAGTNNTAGACTNGGCNAANACTNTNTNGCTNCNNANNGCGGNNNNNANTCCANNNATNCGANTNNNTNNNANANCNCNNGCGNNNNNACNNTNATNANTCGNNNNNANCNCNNNCTTNNTTGNCGGNNGGNTNAGNNNATTNNNNNNNNNTAGNNCCTANNTNNCTATTANNNNTNNGAANNNAGNCGNNCNGGNTNNAGGNTANCNNTNGTNGNTTCANCTTTGNTCNNNNNNTNNGCCATNNNNTNNNNATNAANNGNTANNNNCNCGCCNNNCNNNGANCN
+
#$$#!!!!!#""#!"#"#$$$!##"!!$##!#!"$#$!!$"$$!"$$!#"""#$#!$""#""#""$!$#"$!$!$##$"!""$#!"#!!$"!$#!!#!#"$!"###$!$"##$!!!#$!$!!$!$$$$!"""##""!!!$#"##!$!##""#"$#""##!!"#"""!#!#$#""#$###$"!$!"###!$#"##$"#$!""#$##$#!"$""$$#""$$"!##$#"""##""##!"$"#$#$"!"!!$!"!"!"!""$$#$"$""""""$"##"!!#!$$!#!!$#
@r7431
ANGAANACTNTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTC
+
$#'&*!)')!&+'(%*&!+$%)+"*(!#")*'&#*!'&!)!'()&'"*$&&%''#%!(+'+%*'*#'
@r7432
ATAGCAATTTCAAGCGACTTANATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGCTGGCCTCCAATGGATGGTAGCGAAGGAATCGGAATTACCGATATCGATACATCAGGAATATTTGATT
+
-9+4($3)3.,==:)8$@)#F%$,'B-'>@C;;*&0.1>36?"9":BA01$!A03><'.$D74)3FC';&:35=(-B7:%C-H""6/:D%95)!7(#?'"<%:5:5920-G-+<!2-4A-GG!"&)FA<F)$)"++63/>*C4=!
@r7433
GCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGG
+
9,%DAA;:>B2='"!5/*@G%5.D9"79.8::1%*7,!//12)
@r7434
AAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGNAGATCTCCAGCCAGNAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCT
+
;G7)/F$#$E?/1$&*%.C'F<+=B)-F0D:5%!%8'4B$#&A=C),20F@4>A;1<DD,A!)'"@D<-CC7>*9+60C.9'5E7;"&H@$G;78:25<8'G%4FEA0B%;(76:H*B3.FE/5B$*A:D@!90.%""
@r7435
GGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTG
+
;??8D751E(<?/!H2H<86CF1,7D0!,*#ACB0F/H25F.C*08<?.'C=
@r7436
NAGGACATGGTACGAGCTAAAAGGTTCGATACCGGCTCTTG
+
,"3>*C(9D$$C:%!F@+.G>01F7(#2)6(+"@(;!="6F
@r7437
GTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGAC
+
2;)<E10@=G:B:F:9D</#/7+*B+"D"(.+#,2"CH<2!9
@r7438
CACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCATCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCNGACCAC
+
)29$D,<$3>C+A')G>+!=-B@@1'78=,6:1=:&?3)C1$@F?&E#>'D'E))?;B-=+?43HG+43!6/E;82#D/>F8%2'-1'!"(>H7?4"*?:"2
@r7439
TACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATNTGAAGAGTTCGAAGAGCA
+
F)(CE?@@;E'68643'G/.$&23'(9$*H?@,$&C?)F?#">BG.@=?.+B41'B8+9.3#*51=-7&#GF8E:E'9%02;371)("H1E>B&="G/5FF45>&9H&B*3:
@r7440
NNTCAGCGCNCGAGGGTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCG
+
&")&'&''$'%)(#%!'#$+(+*!(+$)&(!"*""$"&"%&$#*%+'((&%+%!+*"%%"&*++*"))##!+!($*(*('##(&$!)+((+&&)#+&!##+''#+
@r7441
GCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGCCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACAC
+
=:-5=,G49'9H6;6,=1/-!@*5:*?=0(6#,$4$(%?">#)?(9.=C2%84EG):4@5#(2)B..2;E=.8)&5%"%E;/1!-H/'DDA=;7A)1/>E87:<.$6$,/'32&!F%*?F28G"A=@72"F"BD?BB7C:AD%&''B720=F3DF%5H2BD>9?./6:*?"=+$&DF4GC
@r7442
CCGCCTCGTTCGCCGCGCCANCATAAATCACCGCACCGTTCATCA
+
0-A0.7+!#)3A&@&2)G"2G1BE/&<,1@-(,6.7A-+"8('$A
@r7443
TTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACC
+
!8B.-F/GB332,#*-%9>1"(1*9=E=,#,*;HF9@E@9%,<)>B87GG+E6<6814'ABAB@'H>E9:A.)(F%G#:E?53<1&2FE*CA=F75660
@r7444
GTGGCGGCATACATCGCATTCACAATGGCACTCTGCAGCTGCGNGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGC
+
?*?#.(>FG0.HF#$?DH,*3EG3!!>-.B&64&F+HE-HE'H#@0F3)!.5;C1;"4/@"'00@E<8%"C/;1D4'.,/E2#)$#@"2EC5//&>3.+5)*)0>H
@r7445
TCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGC
+
219D(B#H--,1(3A>@:@3@?F"1!D2("E;DG$!2;*2,9<H/D)B1$
@r7446
TCAGTNTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCG
+
F20.;@<C"*!?@1(;FF94222>(=1D#64@E0:D'18";97,"<>6=$(%FG"48.A53D/7+G#6<GE5%'529.B#"20'./A',H3B'=E%'(;07140.%DC:E!8?G,F2>:>#
@r7447
TNNNAGGTTACCAACTANTAAGGTTGTAGGCTCAAGAGGGTGTGTCCNGT
+
%!"")*+!!"%+&##)#!+($*)&(*)#%*)#$'$*!!(&%&+#'))(""
@r7448
NCATCGTNNGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATNAGTTGCAATTATTGCTACANCATTGCGTGCATCGAGTAAGTC
+
"'&$()''$%+''+)*)*&+')+!+"&*)+!!*&!)")+')')&)"++!*(%#&)'*!!)(")#$%'&+"&"("(!*!*#'$&*#!'+$**#%*'##'*$(&
@r7449
TTGAGCAAAAAGGGTCCGGGAATTTCTNAGCCTNGGTCATTGAAGCCTGCCGTCGGAGACT
+
(&+&'#$&!'''"#%"(#++)!!")$))'*&'$"!)'+*%+$*"(("+!(+&*&(#+*"*'
@r7450
NNCNTCTCGATATANCNATGNNTCNCTTGNTGTGCCTCANCTCTGGCGAAAACTTGACCTTNCTCTCCCATATTGCAGTC
+
"!"!)"')'"!%$%$##**(%!%*'''&''*"(*&(%%&$('$&*+(*!#"$&*&)!("()"!")+'(#&$&'(*#"#'%
@r7451
CAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCT
+
2(2:+D7?A,&D6<>.H3B?,8=8)'/)6.9(-?,/A5;4@&)%"(103@A?-!,/.)"E(==#(4="F0G7"H9)2B*#;G67(.1#B+7:
@r7452
CTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGG
+
-6/@-1G(*HCD/C$;@/198,ED;.@D9*DE+#19&32$"E00'+1/F
@r7453
TTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTGAAATTTGGC
+
;%%H+HC05(&90"(?2?HD:=0.@@#+71"!<9D5!#?F:.A4A&C&19
@r7454
TTNAACNGNNGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTATAATAACCGCAATTTATTTGGCGGCAACACAGGANCTCTCTTTTAAGTTANTCTCTATTACATACGTTT
+
'((#%"!("!&)')++%$)'(+%&!%+()#!%")%'+)%'"')#)+$&"#%$!$!&$('%#(!$('&!'!$''!(++"!**&"$$%##!)')!%"'*)'*+&%!+$%("++#"("(&'&#$$!*+(&&((*$($)'++"+'&
@r7455
CTTATAGCAATTTNAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATNATGGAAATGGTCA
+
,.<:DH))*1!#+&(?F'<H)D"A081'=.EA1'G!%)2A9)F=3=1>>(5:3-.:$"E9,%;%89;1.:(6B?
@r7456
GCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGG
+
-&.""%+HEG#7B!+;D(C5<%96/58-0+@E<,9?<@D8+2-"+=;.F>(,94()G(1-A-22?GDA76"F;A#,/$G>.CA"
@r7457
CGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATA
+
-A1:?FB/='4/1$2$B3D$+H$/83A5+1!00(E;,E+,:<7*?-FC)/#1D/.>02(5G3:<7&90$!HGFC"".B=D#
@r7458
AAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTNTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTGAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACCGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTC
+
E<*;"!A"F649)C&$E"+9H6?AB2>/!-/F5+(440/#20?AAE3$.E%3<"FG#404F9=3<-3E$=E53<&9C#8H/8.;G"(+99,(/'6?0@7);3A;A8HC'D6&?)B/0&?9>2.7+&,8CF"7#,!!#G!@)>5<7$43A)8#;@##EC'"C,6+G+=1808*<>5377?='H-@/#485?%=7/C/H6(7*3D2G(*'9-F:,7<%/#1%063<5<:5'%G4,"A#:004.>48
@r7459
CACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCAGGTGCTCATGCCCACACAAGTNGTTTAAGGATGAACAGTTCTCGCTGGAGTNAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCNAAAACGGACAGTCAGGGCAGACACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACAT
+
8'9H+<2A1<>4#:6:33)3'$4(#'2'9D895##;,6.1=2-(!.&'@!C!2)2?2;G/;H-3F(7<&"#,3'*G3EC21E"/7A$&<8$FD/1+9;C*,57B2<C"FH6-9A155H55%!9@%!;9D(*<4!$;7,1BGD7>EA7B$CE76+3F=F@&G&)!<,;'8!=*4+%E9E,5<&F=&1-!@>F8GF7:H4A$7CG),@7>*!*E02%*9CE;%+-(A+?""@$"2751*DH%(F65#%2D,@."@A11B6E
@r7460
AGCCGTAAGCTNGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGNCATTCTTGCGGTTGCTGCTTACCAGANCAGCACCACGNTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGTCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTNCCG
+
+A?/%$:;B:8G4!=6BC0;86?%0@D4>#*BE?.@G)#=F'G(3&8#%4C9EF<?$/,6#F%,E0C0'3>03.A4*93<,87;44@447D.9'E2=63>B1/@H$;!DDB!+C'B-&G<,A)@97A.6G7/'4('?/E'5,!&*>D-#;BFC<;!/:&&#=411CC(%<@8.2>*H,)#)
@r7461
AGCCANAAGTGTTTGATCCATTCTTTGGGACTACTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTT
+
=!$B:EB?E9G&(CH5B31CE.+)2<C4G7:2%#D%8;5:G0H1#3H33H47F7:G'+C+=5/E9*<)"#*!%8@.C'(!)(
@r7462
TNACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCNAGGTTACCCGTNCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCA
+
*"++)'&)+#('&)#+)*%$&'#"&"("!"&)&$%("'"#*"#(#%$'#(''!)!&&$(+(*)&%'!)$"&'+%$&'#)'#!$(!"!#%')+#!$(!'))+(*#%"'*&
@r7463
GTGGCGATGTCCCTGTGGCATNACCATCCGCGGAAGACGCAGATGCCGTCCATGAATNA
+
?9<0'1G.*1.%'37:%?2')C1=?5/#-).?/+!.6!6FDF*077.'!?24(A!(7<B
@r7464
GCNNGGNGNGAAAACTAAGGCAAAGGTANTGCAAGNGCTCGCAACATTCGCT
+
'(!$(!!&%*#$"+#%%$'#*+++(%$!*%'!+%('!%))"%(!($(%&$+&
@r7465
AATGGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCNGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTT
+
EA-6G:<5:AB774G>/'<)%',#F/2,H;;:(".0A'6>6=7".:7<)BC6CBB/;:?F&'!@!C+?4509>=7C"%"<D+#026*GF65H4-<G=4;<!@(<$->?=)C%24*31@&DC*750,7<=-.,38ABE4?)>BH+4'*)!A>/"G!DC9#7$G;?1F8/=@(%.F55?A2(F)D"-;#!;!/6;$+-F"
@r7466
CGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGATGAGTTNGTGTCCGTACAACTGG
+
D!D!F8+<,8+&3'8(0(2;0/$%6%2D(D*:H<!FA*@H&1*=:))&@$$05H*5D/'F@H$B4D,1-B?8&7@!8'4=#"%6<C(<09F$8!/;A33,G,:CB3@C##%+&"'F'&3;1G<1B2*
@r7467
ANCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTNCACGGCTCACCTGTGGGATATCCGGT
+
(#)*'*+'!+#*(())'!&+(*!$+(!%#'('!%!"%'(&"%+$(#''*!+$")+##%$!)!+%!"+&()*!)")*+"+)#$%*'*&&%#+!))&$(("
@r7468
NTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAAT
+
#.3GE7.(-',B'.-B&?0.24,%3&#&3A$<F?A3:+!D%'/+1&&A
@r7469
CNGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAANGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAANCGAACAGAAAAGCCCACTGGACAGTCCGGCACTGAGCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGT
+
#$;7931/H$D"?@:D@9.D#<%5?%64%*-F%@/;8"@5/*3G'2':A&>@#($*?="")1)6%*>9B:5!@G(>*)!"<)8G,(6@=85$7>"7<!1+=-A!5AAF:+F5"'/.!4>F(C**0"7#:(?!;=9="F:-C%E?/A#+,$%:8<("/8;>&C049"/HD3,11BC-"&)+66!:G53)E0;:?9<<B580
@r7470
GCAATACAGGGAAAATCTTGCTAAAGCAGGAGTNTTCCGATGGGTTAAAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTC
+
AE.5''H$0/,!D68H12DF$94%(D4B0(C20!0D2*#$?"%7@='&8FD,-1%>+EF#!!(,8"#:752*:B4$@.+@<-&H9D@D>?>F0:BEA<C=4>D!$#+4'(-;@+@6:,3A6'($BG$31(G@AB*+6
@r7471
AGAAAATGACATTGATTTTATTACAAANGAAAGTATGTTAAACATTGGTANAAAAAAGTTAGTCAGACTT
+
5%C"2F:&"A$0=@,D3=9//D>?!80$!D-*01'#>D/2.(38.HA66B&16##;5A;@A(54A7:/+,
@r7472
GTGAGGCGAACCCTGAACCAGTAAAACNACTTCCTGTCATGGGCGGTAGACCTCTAAATCG
+
8:8():<>&A;-"/9EH,*.&$&&DD?*.BF)>*>?)#&=E4.CBE+;//+>4D3#B?6GC
@r7473
ACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTT
+
F3!0((C#0<D67&='8$($"1(-0>,*%"DBE"=7@7H7G)A$F#,2#568<)9CE)5C6/94G46
@r7474
ATTGNTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCAC
+
=9)34,5.93A3(./&!-&%8H;@.@C#H<<7-C-D26G?1F+4E
@r7475
AACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATG
+
GC7E?'!76*G>"!H)%&+;D6F16-",@##$039#1/,%.->95G%F8'496'322$?*@'<G3B?)3-3E,#@#8A&;62>H#9D4<+;(0*6#!>?6@*..:3-)H8.B:.1)D(98,(:>D@00H394-H.<@:!B%/<*<1FC;"$@.D8#2!1##&(-B><E77H<(HE-;?(&A25-$'D>%.3B63!2+B&$,:0?!'8B'11(>-*=F=>4""9>,;EG1.A0<3)A$(F8,FH%GE022=.;'+9'C!1#
@r7476
GCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGAATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCA
+
B'BF*1+)8)$'B%?@=.!8!EH/G/$('=;-6!1:0H4<?+?C)D!"%:683()BE><6A!?.1D,.2$G3('=:H8?%98@3B-%B$*6@(;6/@?+&&1)(=A?>("%
@r7477
ATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGNTCACCGTGGTGAGTTTGTCTTCACGANGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACCCCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGG
+
37#"8F%'">?>.%)7'.?&-C)+0*$@"'D8("-'C%;7E.(6AE&6-=104-?5%@B05/201!C$<?5-B/"!3@=729"A7ACC<B$9+8(F<:E4<&1>?#*13>F</&@1=89FDE,>8)A");#E@9CH;,'A5B7@?/-E*1"9+!-C(4@+!,8D"0$%4GA+9?6HD<E1*.%6)G(&.*E*F8%3*@H/.!0E1.F/7HF6/(G/A.=8=F530*,
@r7478
TTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACNGCCGTGAGTGCCGGTGCACATGNG
+
$5!;.@@%%%-%.H#A,+CE*D2$@+11;H>,-$DE!9/'-@->2*HC80B<CAFB3*$H((+B:FD@3?!>$BB$":2@(!C<B34+HH44H885=/&(E=#?8F@6#3.<&>8G6
@r7479
AGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGG
+
B8C8GH?**0'$1&?!;9#4G0485FD:0:>C9&'?*%@,1D1A<7/9(/-D))D+851)<./&E%(826H>9,/A&##=FE@.0G?H)#*4#="(*9F9#D>(#7:G*B#7
@r7480
GCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCGCGCNNTCATCCNGCATCACCACATTACTGCGGTTATAGGTCCAGGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCGAGCAGAAATCGCTGANCACATCCCACGCCTTANGCTGTGTGGTCAGGTTCGCATTAGAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCTTNCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCC
+
+)#'#$')*(($$+$$(+"(#(#"'$"'!%'++%*"#("&('(+!"*"$%*((#%*(#%()((&('&*+#%$#+($*)#"&&#""#()#$+!++&(+##*"!$'(#+*")*!!''!*+&#+)*%)#+!&*"*)"*%#!"%*()%"$(!!%$+*#+'#"&#!$*+*)!$%+#&&*+$(#"**+%*!'*+"&*++('"+*")%%)*#((%(!"*&!"&&"))#!+"%))&%!!('$()'+"!!%++)+'()+'!!+"%&**!)$'#)(#)'&!'&)#*#"%"(*++!$(*"!!"#&%*('#'+'
@r7481
CCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAANCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAANGGCNGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTNCGCCATTATCGCCTGGTTCATTCGTG
+
3!1B%4!5)5:<4(.-:G801-%E-8$36H2'H?)>@)3%#39G.*&&7+>)!-%F$E6)-%70>E"0+&#>6;H-0/3$*<EE+;2$E@0D'&*86<7*4>%,94.F?>D0B5!,B;@+0F5:0F*2C<!D/&60E&:3?=):
@r7482
CGAAGTGAACGAAATCCGTCGCNAGTGGGTTCTGGCTTTTCGGGAAA
+
D$<7@.)>:5+*"C&"@=.A%.:'GAE2G:'>3'B</6,GG77F&$!
@r7483
TCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGGGCCGCAGCAGTTGTCCGGTAA
+
C,1=*:/6E"6D%#F+&$;5;>)%EB$7>%+(5'>,"'HH#.(;'@=0>/6A7H<,<A=&B&/#1(HF?(9E77,'A*F'$H86,8(F2A8G%-!D.%&-)&!5%(F9%7;:=C/08DB
@r7484
TGCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCNGCCTCAATCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACNAGCGCNACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGNAGATATNCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGNACGACTCCGCTGGCGCACATCGCCGGGCGTGGGCCAGAATCGCTGATTCTGTCNGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAA
+
%(+%$#$'&#"$#"%')!*)%(&(!&'%*$'#)!&)#"+**(**)&#*!*(%#!%#+#(!"#"%%"+(')+&"!+!$"#*!'"&!#(&%*''*+$$#'(*#)(&((*(*&#*#&!'""(!(+*''!))(#&(&**$((!+("#%%(!!("+"%+&&$$+#'#(!'#"""$$"'"#'"""%%&)&#"))$"&$+&'!)+&#$!*#$(*)+(*%")(+''(!!!*'#)'&)$!%!(&('()**)!"&**)(!+!'&!"%'')#*$$&+)$!%"#(('(#"(+$$&+*$%*+''(*##!+%$$(''*'#!$))"*)&
@r7485
TNATNNNNNNANCTACTTAACATTNNANGTAATANTAGNCNNTTAATCTTTGCAATGATTCTTATCAGATACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGNTTGGCTCNGCTAACACGTTGCTCATAGGAGANATGGTAGAGCCGCAGACAC
+
)%%*""&!"#("!%!&&%*''"*)$)'!&$$(%(!(()!&"&*%''+()"%'!)'&("#!#((&%#!!'(#&)'$#$!''$'&)*%!*"$*!%'$()*!*!$$)$)$+)#+"$$%%*)#$"!#"+*#+&"+&"#%()(+#(!'+)$*)%*"#$%#(*!%"+$'"*'*)&#(!"%'%"(""")(("%$)'#((+'!'('%+"
@r7486
TGAAGCCAGGANAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACA
+
.B)A)D'E+&!7C38?,9('D?8"6(.@*20FC7.C!$B$D<4:,H&(DA:/2:E--A8E5F98BD?2G<F?
@r7487
AAGGGATGCTGAAATTGAGAACNAAAAGCTGCGCCGGGAGGTTGAGGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAG
+
971%E:%28:5:=8$"DE;0DF<8%0'EGG#35F/37:!8&&#C?:E@E$D58&5GB30EHA$<=;-D0ED#-AD$H&9
@r7488
AACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTC
+
$:+3@ABF%4$E'<>)/9+G85GHFA@'7B(B%8<5GBF8!BB<12.4'EE>0(#GA$06;522F4>=?+:D??/"@4+,,$(:A4.!BC-BB/FED3&)%>HC?DE@*&.4<!>2;/@E1+%&+"1B-D=11
@r7489
CNCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATG
+
$#7+C.9:,3%5%81?C>4=1&&/2""80"8;*.+1FF=?1<E@*')*2%"3"G.
@r7490
NAGANGNNTNAGAAGCCCGNGCGTTTTTNNANNAGGTTGNANCNGTANGGAAAGAGTTTGCCGAGGATGNCTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGNCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGC
+
(#&!(*#&(!%%%&('*'*&((&$'%)'!#$(%*&(*'*&)%&!%#*'+#(!(&(')*)%((&$&*&"(*("#+!%&"#%)$$**!%#!+&("!%('+')#"%!#&"$'#&$*+!('$($'*+$#&$"+%&$%"'+"!&&&#'#'"(()(%()*%'$#%)&%("+$(!%
@r7491
CTTTGAATAATAANTGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAATTAT
+
$$+*)%(($+%()$&!!+'+'"!)*%$*%#!$!+"""!%*$"!+%!)!)+)#$"+(!)!""&"$+!*('(!!)%")!%(*#
@r7492
ACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCAAATCCCACAGACACCAG
+
9'B+';0!E1D=C3/)<+C#-(3+=&%2/?0*(G"265><(2;A560,0*&6E8=47C
@r7493
GCGCGACGATNATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACCANATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCTTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCC
+
<7(3G-E69/90@+$.&(0(;+7G<6F!06%<)@14*5<;"2C7C6&F@<!>0.&4&$9/;2G$5"+;AG)")';,8.?..>&62@19D<"%!G%(C>&0>,(!:2@<*<E2%<7**;@H=AF8$-"8%C9?6A$B#F7@'9A.9B6"?EGG39B4G),22/0%"D49'86<&?%!5&*5?012$0D0<4,:9@?C$+"B#4DD3%68'$1;"1FD1>>!1+'
@r7494
TTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGNAATGATTCTTATCAGAAACCAT
+
C9:0F9FE7'FCF#>(("GC$30F#73>;)+1?>3E(5$&1HG(5<.F8/&%<:$FH,;;D=7.3<>E<@#=E<%:7468"4
@r7495
TGCGGATATAGAAGTAATNATCATNGCCCGGTTTGATATGCGGATACTNGCGGCTATCCAGTACAGNGCCGTACCAAGATAACGCGTGC
+
:@3!H$%.G/=%'+(H(?77;:6)0&(CHGD5G#E'373;A5"82B;,!'!=E)12-:(*2C"/D=DC+*!$(>:BB$/:48'9D42:F
@r7496
CTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCC
+
&D0A(4;!."!+8F)60%B"2?;0"'.'DD;/6A23">9B1(8<:C+F"!0E%(
@r7497
TTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGGTTCTGCTCCTCTCGTCGTC
+
*H'#>5@'&=*7=0&54B>.:"#@&AE;+('4>*<=5'=%)%?/$B('C(?'=#=4B1"+GC!D0)?:G>/59C98!32;4C,
@r7498
CGGGNAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTC
+
=!G3C-//A3-:2$5&((%-)#6'36"(>+;#(?105A/D>%>19C)%2##86*,16?G?+"'43/>+1(
@r7499
CCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCA
+
(5&467A#':0=1$G7''F0H)18!!B!>C":B0A!+C==?:A:.F,,640FG,!0)2FE>!&GDB-)*9E%,8%,&!8G'+(;+#"=<DE2;*8<(7H0'*/A?-
@r7500
AGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAGTACCGGAAGCAG
+
?)/!79?>26E!H6$FH*8A*>*!=H14B'D99A0B&'@C<,.!"2>)
@r7501
TTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCC
+
)7369'/#=2->**(6<?#F:H;45G:&AD+$H2*8H'$"(;;8E>#.D;(7D1#-$%=5D'?/7>G(8HG'!?1-#9>:43=G$=-$'.=22&7,"B8)513$8>7E7D40B;)@?89/
@r7502
GNAAANTCTATTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGNAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATANTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACC
+
&&()''(#$!$+#&#*+'!&+#"*+%(!%*"#)&%!!+"+'%&"#))&#!$!&!+)!+!()#""+)+"#$+#'"!'(+*$(*!#'$#$+*'("&&(%++#$%#$#&"'"+*")#!+"$+"**"'#$)&!&%())!(#*&'#%"!+$*''%%(#))$%$%)(+)%*("'(%$))&&&*")*"%'"%!$)&$#'+'!&'!#&%)*")$'*!'
@r7503
GCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCANCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCANCGACGGAGGGCGA
+
F$C:%2."@/1>H1%%/(AHB%6=>8?#2'/5#@H357,G424;F=((5C4)>=.3:(*<81+9A:6/3D6'6566E=#DA!.0@9H61%>1G<C20*>))06@#+;36C9"?A
@r7504
GCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAA
+
+'4-@/6AF(!;>,08#'#2B)<+6#%%%B<',FH#+*7B50(E+:F&"EB>:E<.
@r7505
AGCAGGATCAGCCACGGACTTTGNCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATNCGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGTGCC
+
A/:++*"&.E2+3'%7#?@+"8C$/$B:;)E+0<,-1=0?6A*.(.8=A-H'F-7)3(-.D>G#F(AG!B75*?='45DH"0?6-?6"6"<A3$=77C,0C'-0CB-DA9@#E:*2465E5)1EG9.:!
@r7506
CACTATCGGAAGTTCACCAGCCAGCCGCAGCANGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTA
+
.*7G<#!C2"GE)4C*/7C.#D/4)6-H,(7"<;D&##"&2'+-/G;AG:>7614+37*F0*#1D6+;:80&D7/4=G)<47">A1G54GFE;-2D4C?C;1)&E8F?8.>;#.94)<.;HD=8H(&C/.:6*4)9H)"1=+G75-:FG$*=6F=2)(C=#>9'!
@r7507
TCCCTTGCGGTGANAGATTTAACGTATGAGCACAAAAAAGAAACCATTACCACAAGAGCAGNTTGAGCACGCACGTCGCCTTAAAGCAA
+
5F-=EG-84<33(<)57:2,.'96*-5?A?3#1'5=@/.>5/D)&(-*)"+C87/H#>*,45"1&?1/"/FE%26B0AE6F#F2!42=7
@r7508
NCCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCT
+
)A"9?<.#=64A8(C0""C%D78"(2$D8=+(%G-%+2H:-42F:BG8D(:B!8+B*++D!+FB<6A67
@r7509
AAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACA
+
5.?058EB$($2)$."9&E/"<$.0/#C:F"*%'7&,4CG
@r7510
TAAATTAGATTTTGNATAAAAAACAGACTACATAATACTGTAAAACACAACATANGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGC
+
<=B4?&!C;C#-&$$:EB#+'16;)C736/?A93-%7<E3&6A*;+DBF7:B'8E8H:=>!AE?>9'>9-%*>2"E(9.32H=1@1)2D3>B5+;GG>'?13%%EB?&ED34-G'F;.%*?0E8>C,FD31>:*6=*9<
@r7511
NCAATNGGNANTGAACTCGACCATANAGTAATGACAGAGGAAAAANTTCACCAGATTAATAATTTNTGGTCAGACTCTGAATACCGACTCAATAAAC
+
%)()#!'*$'%)"$($##)$%&%##$#'+$%($(*("%"!+*%$"))(%&%*+&"%)"&#%)''%!!#*!&')(')+*#+&+$&+"+'(!()!")("
@r7512
GCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCANTCANGACATAATGCAGGNCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACGT
+
=1%=;G;69AD)(F15=:F1/=!.H:+D9!90-5+0/,2*%E=(F5%4,E!!B&C3GFC).-7G+CD30$G;;<G/+H)"7'!;(0/@"$)AD9)==6DH/','1:23G0)2"&%'.G-F?36.D)-#CA5**A2<##3@%F,H:1-69*G=-230%1FH,F=F4G7.2+#BAA,/<5>@)>?-,-E9F=)9<+0/435G2:<+:00*8<=>!GA
@r7513
TACCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGC
+
,G)<<<'52B(D=.AA0#%194?20A644(78D.4H1:(1(@7<8%=="6G%,$536&3@B#2CD-1;>,7<6!6H"D&D,H@#6&9A,B;25-E:E,A&4!@.8HB
@r7514
GCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCTGCATNTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCTATGGCTG
+
#F=FC94B/-A<4;4$<F=,!-2=:'0(.9(<9?;,:=<.!6>-GH=:G&?%%HG*$5H6B65C5,/#FA-52=<:>0>-$!"69AH(33DG'B?)7:+!=BE(73:);D@1;B*.B"=>*+%D;:2?+BF!'=)4F;$+6,<@4.H19=H<F,F!$512&37"DB<#!!12"=C.5)4#A&AE',%,=@6/":='?04288-7)!":9)D%0+";3:(2$$31H:7;42>
@r7515
TNNGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATNTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCG
+
')"+)%"&+++')')%&'%"*&%*%+**!("$#***+)'*%%!!&&+"+!+%%)(&+!($+""$$('"+%!(!'(#!!*+%")+%))#*!"&($%#)))'#)%!$$)+$!$"%++")!()+!&)((+%#)
@r7516
ACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGAGCTGGATCGTCTGATGC
+
:H7%)-?G@50?B<@;@,=%>:GE9")3)16F$>5,'BE>33'!(9G#1-2)E#BF+4)3:,2!8$@*$4?/G'#.<D0A150>*/2?G2;3<5*BH9*@@7++#&D,)!B*#/;:
@r7517
NGCTCNGNNGNTGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATT
+
*'$$!"#"#(&(&+!%#%+))&*)%()+&*&#'"))&'"%)!++"(()'(#'$"!($+"'''++'!%)*)+'''!"*!'%)$""#*$"!++(*)$+'*'$*&(#$)%)'+#
@r7518
GATATGGGCAACTCTATCTGCANTGATCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTAATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGTTGCATTATCCACGCCGGAGGCGGTGGTGGATTCACGCACTGACTGACAGACTGCTTTGATGNGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTT
+
*+%%$+!#)'#$###%%%%(%#!$&#(+!"%$+(&(&$+)$'(#+"#*"!"#+*#$#"*!"!+%%))&+)$"&"#&%#*'#%*)&)'+$(+)!%#"#!)#+**$$#$(")"*&*$"+*)(+$'''#+!"###(""(+*#*!'#$)#"#("&*+!($(#$*!#(%&%!%"%+)%%)$#$$!)!*+%!"#*##+!+'+%'#%(""%##)!%(!('+''!!&)$*")!*%!+!+)+#++')'%%&+&%(**"**$%$"%"*!%)%+&#$&#*!)&#"$$"'
@r7519
GGTGATGCCTATTAATTNAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGC
+
9!/1;E(C**#G,/1C1%9%9H+D//*.#2F+(A?=2.=%":,*E!,5+H,2$-F4<"/G1G6G+,#)5<&/6+=D18#=&B<('5F+H?<+"-%39@F+>B1,,;"5(960&C<<%.9?C!6;H..(()6EHF1<+<.A*6=F+@3(875&#*C0'0BG%@B4?@<F;3-"HE+%&D2=B-D;>67$:)DHB
@r7520
TCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGT
+
C8&CC-64#9C.1F5*"./;@D,F$&3*,"4-2!?+F!)CA0<C.*11/A:;C5=D4$,)(!%-6C-9+4&66+
@r7521
AGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATANCGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAG
+
8303)4*/F)"C"7)"/@B0*D,)@,-;G28H+5"!A81!09@4?;,D51FE4A"8C3&&>>>.B?D%+GE6(F;F#/8?<8$/G?"D9G-%<=)>47G8@#G!)F47,3;0!F?1G/D27"0<*)3H-40.@&6*16#5/0.0%%+$?A4<@B<E@D2)82;'4?(H/E.C!17;8&F33>C0//A2*=42$'06BDG'#59$9&5&15F*
@r7522
CTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGAC
+
,47@B/3C8+*,&<4D)H3>,)2E?-$".<:"4D#*0#32:+B&#5*%A48)7F&E429B
@r7523
GAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCNGGTGGTTGACT
+
<)34,32=6E=+;*7AG-$(!#H6$';;!#0#G?/B<9*"=G;=&2-?'-19?+5D(44."=8;+=
@r7524
ACGGCGATGATTGCCAGAGAACNTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACNGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGNTTATTGGAAATCTTCTTTGCCCTC
+
5(+C'C14E'>&%6?58@?H%7.)/+9(&/'A*()?@)E8%%===;?<;:!3;47*.?D.35")H!>>'F9(@@(55.3-H1/*<(5&8/@"GG-(-#34'(,BB=H41(A9&$79:E##A(F+@HC"/EG$B":%)HAB>)CFD@,9:D'6.-@=3%%#D*'/E0GA9>18?6;6C+<<(3#FH:=B874?
@r7525
ACTCGTCCGANAATAACGAGTGGATCCATTTCTNTACTCATCAAACTGTAGGGGTTGTAATAGTTTANCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCNACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAG
+
,=HC:C@F<-FAFB-8=4"(6?+032B7*BH">?D/B#*H#3B$8?-$)C#40HE%!@,-BB6;H3<$FH;*=:9B'C5<H%!-1D"C8-FA",,HF=6D/A2,/"57GHB%2*D&82("*>@%,21=/18392A?70BE*,B.?&1$50=*&";G+<9><>.043=AHG<?:D#@97DG#A$$>D$!!D3$2.09
@r7526
TCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATGAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAA
+
9;8EF8'+,E=CH>#@@4B*B5"&@+'3"HC(?D2H*?C7<HD0HH8?@0<9%,7<(AC6?!7C.A;#52/-<*H26:"E?1B3BC)>5*HFE.>)'!6<!3@<>E*C;97#.6+$"/"!0$B..H(0,E
@r7527
CCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATANTACTATATCCTGAATAGCTT
+
1%&A6@2@5D@+3!H4-&6H80<!EC</?@>G)3-"-7#@F0(E<F=B".=,=?7,9@/.%8$=#A+=5(;.0!A9GF@3%/+0*'7*9!4BAF?41'%G'1G"'90GG%H-=+<>.@GG41'3F/@9C!'?../*$#,!08D7E-!/8**-<;-A)&%1."G9#6:)"@=#*6""H!())69=HA*3:(*;)#G+GA)0D4+##6C1?9E&0#":H2/E+4+/5AF4-<-4*B6=383B0:CEG>=<1#F$@/97HC<":F8.;5*-<*""-%(?/GF%$E91&)42*4D,C@9?7/.*9;/?+24
@r7528
NAAACGCCGTGGTCAGCGGGACCGCCATCGGGATTTTCACCACGTCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACA
+
$>.H7595%*C!?*55.1+=$$0&<)A,CC%(.AD"C9.%%0:%$5GG3:!,EE+.+7B?F(D*D*=@6./>8E16--:933H+=>
@r7529
GGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCNTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGT
+
B&!A:/.<#0>;E8)96<*"B<<&=>05<93;514+4<BC0B*G78"4#>(%=4F<H@:,8<4C#H<#/->>):4"C4AD81H0(:/#426C+C$"5
@r7530
TTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCNATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCNAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGCTTTTTACGTCAGATTCTTTTGGGATTNGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTC
+
H(9&'-F'H90FD=-/$>%7!B$%7D5<)<1;2)?$1#/@;8G<;0&!+HF+GA65(%"2B9)=>>3D(3;/9;DDAG<4#4&'3@.</'8$?"B)4&*=C%=".23"D+=#$5D#7$-+:"@9$>7#?#1.0+!C.$??034-GH==",?F6A/'D:/"G/9>=*)@C;EH6'A/87G.?8"77%E3$-6*!C';<@918:H6/-=->%%6>,7@)6<;,5G1"+5*A?'"6316,>&A4.>,.=620A$.8=HD(E2(561-?/!G>/11$<A''*>?D!"FA.F?)B/.5>$))(.)/#99B7)61F.#/3F+0*(3$02=/D3:41!<35@,%<4*3.;67>?9<FH8,+7;'+--C-%1A(%A7E5%)5F08-:>
@r7531
GATTATNATGCGCCGCCACGACGATGAACAGACGCTGCTGCGTNTGGATGAGGCCATCAATAAAAC
+
#.F$F&+!(ED4!-<.=6-)(B(%FC:+B(:7E59B;'C?744H<E%01.G%FDD7<"50.(1F?"
@r7532
NAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATANAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATANGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGC
+
#?2$)8$(F0-F5#2=>@E-@"=(''-3&6:.3/9>(;3"4%%6/8)")747.1C4"FC)378@B$@B?D76C,=712&53C2,/B0&20D%=*-3+:.%(18F2$#B7F(;%9GE'&3($'HD*DB54!)?6419"/H,4<
@r7533
CTGGAGGAGGCGGCGCAACGTCNCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGCG
+
$5:2*:2H-<.+=##,C8&2?3%%(;0?8-?<5-7=8(+,GG=-.!2?0$:.,7125>5@E,'(HA375-F<8';3D*#D@/=4.2CF*0/"$G4?.>96G1*#2E=-
@r7534
CCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCT
+
C10<)'19754F)10'G!#%@->$<B9@9*G)FA)5@.$F)3;E/#A4F17@&;-9<AE2,AAGFA+B&:'<.50+%(.%%#%?<=+?$B3,BB&$@A:H9$-9<DHD.<H@5>#7EH#CE<49GDFD
@r7535
TAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGT
+
HEB7E2F:;5(CH/#HC#(('#0?$&=/<,+5F+F,+)./
@r7536
TGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGNNAGTTAACA
+
D#*;70,H553+<"8;AE4!$D/4';AED#'E9=:@?;"0)*/E335/4=C:6(C7BG7$@,
@r7537
NAGCCGGGTCCGCCAGATTCTGCGGATCTTCATGCGGCAGGCGACGCAGGGTC
+
"&+?#(<"?,@4/3/";6D>C7%-'#$@D);1HG'G'">C)2)+/D8*6$'A$
@r7538
TCTGAACGCGCCCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAG
+
@5G.+;13+>@/=*"5:@(H;=18*688H$!FD=:-/3H?H@2'F&4$56D.2H%<9=6>,0B&1.*8D/2A>(2$&4$!=*:.
@r7539
CAGATTAAAACTACGTTCCCTTCACCAAATGCTGTGATGACCATTTCGGG
+
?B&HB1#GB89F'3,"H87(?H84*5->'@#>C7HEGEF'=5H(2%H5!/
@r7540
NACACTTACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGAAG
+
,*E>C'D-:"04D.<,:/4(HG6#A<:%5!>?)7/-F1<3+=,5>#6-1@-5-F!#H#H7051B"G(DC!E=?H*,0%=$E6@8D>#,70,4E$<F+4%BF%BCH799.
@r7541
CCGCCATCAGCGTGTTGTAATACGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATT
+
+*>HE(9D7.>*!92'0<"#5@90HC(=4>&.1B:0*@,39&<<91;GC5!3E8/389)#D(**(8<3G).;77951G13<E<.2%@0,50AE#(D2:2&1-,8D7A=:8=$C8.'*DA$#5%+C.C9F9(=*6/G"B%D=
@r7542
NNCNNNGTNTTAGGCATNNNATCNACCTNNNNNANNANNNNANCNNGTNNTGGNNTGCGNNGCNTGNGNNTGNNCCNTNNANNCGGGNNGNNGATNNTTGNNANNNNNCTNGAATNCNCANGGTGNACNCNNATANTNTNNTCTNGCGGNAGCGNAGNNNCNNNNNCATNNNNNTNTCAANNNNNGNGGATATNGGGCCTNATANNNNCNCCTNCTCAGNGNTNCCNGCGNNTGNNGNNGAGNGNNNAGANTCTGNTCACNNANANNNTCNNGGNNNTTNNTNANNANTNNCTTGTACATNNNAGNANTTNTNNN
+
"$#$##$!$"$"!!##"!$!#$#$"#"!#!#$!$$!$""""####"""!"#$$!!$"#"#$!!!#$$"!#"!"##!!$!"$""#""$!!"$!####!"$!$"$#$#!"$#"!!"##!!"#!$"!$"$""$!$$##!$"###"#"!##"!#"#$$""!!##$!!!!#"!##!#!#$""""$#!!#!#$##!$#""$#!$#"!#"!!$!$"!"!$#$"#!$!!#!#$$!!$#!"!"##$!!"$$"!"!#!$!$!$"$"$#$$!#!$"""#!"#!"$"!"!""#$$##""$#!#""#!$#!!$"$!$###!#$$$!##
@r7543
ATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATNTGCCGGTTATCACGGCGGTGGCAGCNGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTNGATGCACCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACNATCTGGTACGCAATAACGGCTATGCCGCCAACGACATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTT
+
(0ABG68EF!9CHBHG097?H8>>9?9:<:"1%A/@8D7CB*%24;!H/&;.8+@<'70?4+9$A:9*0?<ADD#?AA58*9CA)6D*906&D(25H-;F2B,*F9#/(GG$9847B29*D5.@?A555/&3H3)@H=+.'?88A.//?CG?)41-&EA(1>0<H".A#F*58C(1H.6/=$%!3#G)#'*A=*39/F&2;;#)B"/B/@!>G(-729/BF@E8>=+H.87--9+5H,A=#1D07$7="4E1D3*
@r7544
TTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACNCA
+
(HFH#9&@-;2,)+506BF>/)3AC2A5GG##7;GH3-##H>%&@#0:3-&=<F3G=(=7933G#@"
@r7545
CNGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGGAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGA
+
%!%-)<':4?622$?9-2-C%(:')7F%2*-8('+-D8,'+(.H#9.D2=31$1>#7:'$=;,!6/!#?5,<?'?<FHF;8>(2F0,4(>;DBEE(>0A$1":AG<7#C"A;C).'$<?2*&<<+51GE#E9-$
@r7546
CCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCCGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGATATAGTTAATC
+
4#.9G@"'"@=0>2@&<-&C1+H@;0A;(?AC43&5G!,83H./,F+C,5#5DE!H7(63)::1=.@#>54>2=@?+<:%B<);..0A63./+F"=-;>-.D;'-D-3C>=3'H984;@DE@45/8'AG+FCH3('A/!3&A'HE3H)%$-HD%H$'
@r7547
ANCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAA
+
)!#"@+.(AD#*&/"%CE55.#1>6F)1>.'(3-)&BDE*8"4+<;G&&=C"!G#G9=(
@r7548
TTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCANCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCA
+
1%!3(6>)@/1C>!*#;EA5<:1C14A@&9(;*H#)H.EB'?@;&H=5HG3'45./G%:?.@D!#(9'G1=**D$#;-HC'B#%$?=D*(!@=?*H9*%(%047;"6+:;-''AB>@<H63B6BD2D:&D'8B<
@r7549
AACCTGCAGGANGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCNTCANCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTG
+
5D5!AC3"@.D;-11E<>20H@;/="84#G,G:C.?-><:2513$(5A71,;1E/A>+@GE/4-$;G!E5)57>-";BB&>78D61!CF2+:";5E:<H!1D/E+&&(C,=&/G.)E2;D;#',GDB!E>@:2<?5!6517
@r7550
TGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGNTGGGGAACTACAGGCTGACAGTCCG
+
63D42(8%("G9HB8?'%C0,??426%(&(;@(?;1?C3A$1/(<9?#2G"0-:6#!0BD&*D+0C59B8H&H=C".BHCG=>$@*$
@r7551
GTATATCGATACCGGCGCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGA
+
69,*@0955+89B!"!"B8="72#1?"5'3##!!H?@,2)##/';7DE0,1;1;HE-
@r7552
CTGGACCCGTGATGGNATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGTGACCTTTCACATCTGGACAGCGTACAGCCTGTTCACCACCTGGGTGC
+
6$"<>=%C!/F=-5D35=?+G0@/2,/E@7<H'3?05.:@*!*E#"#5++))3=HF9G=;3#5-/.EDD<DC:?$@*9@E(7"(+6.C8%9+:#.?*H2F&G!!,6?2AB*"@
@r7553
NACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCA
+
)*7A.!F'51)G'45#@.88:3<*"."6=5A4?GG*F%$?D6=,8.9,GAH*5DFE9&'.@@$,5
@r7554
CGGATGCGCAGGATGACGCCGGACAGCAACACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTAC
+
*A%%?%,(;G$,A5:A5>0;G5C*G*=/7A''#73&>8')/)AB3:!+>0544607*B++C0&#'1-5>#>%1=B2)*C%?A?G"0C+D81B*,?@(DA
@r7555
ACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTACTGGCAAAACCAATGG
+
?F>=%B=E10/$$0E&)%':,%5+8:A(3&BF","6C05@5=E&)A7D%A,11/;3:)-&-2.?-#**B?'A(0-(?3@->?1%?6
@r7556
GTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACNTCCGCCGC
+
-@+9)!/*:G-!B12.+F>>B0F2?5CE0&;0;A+%:--1#6+H#>;:A!=;#3>G=+@B@0D(#0.D(*+0!:-()$!0HG)6)<@>)#)$!F18))F=1-.?8G7.
@r7557
GGCGTTCCTCGATATGNTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATT
+
&+CG18%$306<"##4@+!7B),A478?1;-&B#$"D"B/8/14..":C#1);$!"A(E1880!&FE82;);>&4*!<'GF50:#!DAE!:>/%@"07H@&:=C7'*
@r7558
CNCNATGACGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCNAGCCCGGCNGCGATATACCGCAGCANTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGC
+
'#$')%#%%'+&%)#*#'!$(+!*+!&()&%%#$*#!"(('))#%""&*'!$("&""$(+&"#+!%#&)+"!"**&()&(#!)%#$($"'+')(!+&&)(#%)&*(+(#'"%+"#)#*('"!!$'(()%"()"+)$)'(#)#&++($+"')**()(!)!#'*)'"**(%&$"
@r7559
GGNNANTTNACTGGNATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGGAGATGCTGGCACCGAAAGCNAGAACTCCCCGT
+
)&&*&!!$!('%'*!+"+&*%%!")!("+")"#)*(+**&!**+##%#)(!")"%%*$($'&!('#'%$'')'#!$)*%*!&*)&$'&*!"!&
@r7560
GGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCT
+
EFHF#9D<:>,:8"(6/-%33B;$+!.2DE920>"D30FA+:43):A29D,@?B&2:+7F)1+C78'18+3D6E%H@5?%CE?986.1(,&1;F5%8-5)=&=%'7D6;)A/0)G+)!$@("80#=A#3.,C(>!#9$54
@r7561
GCGATATACCGCAGCATTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACC
+
E?6;34A$.5:#*&GDF3(#)F>#%H<;=/H:"=3B#<*';-5-%,&(H$D++F2!9#+H)#;#=C@>?B8%D%@8CD!@F:8
@r7562
ACCGNAANTCTTCCCGTCCTCCAAGGGTTCAAAAACGTGAANGA
+
'(#)%!&#+$*##)*"('!*!*&#")+*))&)*"*+$+#&++%%
@r7563
GATTTGCTCTNTTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTC
+
H<@CD,'*.!%->E'<F<9!(H(!H'E90?57B6A:51(1?!3*?4/??60-=F9B>:#;(H5:F?D$C8EBA2@<;-H+"-;E<D2%:(9'&0:141G9&'0.=F$0/4$C?>1)1"H5;9=B6@??:9.:&1#CH'+EG<C,@<8:(@=29?BF(=9G5D!$*1DG'H547BE"",;$.)@A>#3A%"6HF"6
@r7564
CAGGGTAATTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAG
+
=-42&?).0,3=A:.?C+7.6,/>6B@6A(<7/)1-"D1E'0+*$7*939:C8)0A3*A/9E
@r7565
AGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAG
+
?A;2(04"2D#>-+>;=;4.6D;.$D1)B$0#(40C0)G)+!-;*4;>7&%#59=4A&?B?(<A40.@.()
@r7566
NAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTTTCGCANTACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAANGCTACTCTTATTTCATCTTACATTGAA
+
!7(!&="$E0*;*."&2-+208.;&'7"(@;+/G&584,1#824;4*.00-D=1&AA/!0%C59468>D!$$3?"&"+6B"-93E4G.,7+3A;6@/8G%7<>,6EAH,#@C;H+FA,/:&@;?GDDC:C=,/<<10A--?H(1+88?E)9E22/:&*B-9'!2CE*<=H=D:704
@r7567
NGAAAAATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATNTTATCGGTGCGNTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGNGGACGTGTGGCGANACAGCGAC
+
&%#''+)++%%*&$*%&*%$%#%$&*$!((#*"*$*+"!())!'+!)(+!('$((#+%"&%*#$!'+&!#%&''+*&)#'$'$+%%"!$#++*&+&""$)+'$&#%'"!#""'"*)!&!'((&**'+)#+)(%!$'$)($$%'##%$!+&!"'!%"!+&''&*"$"%%*+"!#!!+()+'')$&%$)'#"(#)"$+%"%'#%%'
@r7568
NNNCCGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGAT
+
!"!&%$+)*))!&')#+*''')*&&$%"'&"%(*!$"'%'!%+'&%&"()(%"&#("!#"")'(%"'#(+#'*(!('%&$%&!%*$"*+!$"+$%')$")+)&"%*)+)#&*)#+%))#&**$&
@r7569
NTTTGTCGCGCTGGNCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGANATAATCGCGGTGAC
+
"56;B<$H("HF20A-0&8B973'H4+F=A30*?6$<'6''=3)3+?D#:/+@;65DE669&72664;$HC%/,1C#BA9$(8#=:D#,*!7:AA#F(!?BF;:*>7H%
@r7570
GCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAAT
+
H;7!.,>607B)F%#-#$H2CA58;"*0-FH6!="08>>:*3*30?@1=#=G<B$:>4-;%/+
@r7571
GTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCT
+
1,36("+?<5)2+>D1,B'C>=9"6H(<3<%>8-AG8A@"
@r7572
CCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGTATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGGTACGCGACAGCAAGTTTT
+
A%;D(@*+4D70,D#:/*-&A'FAF473=(E<07*H(;73!14E'3F!8:)HH53-8'E,CB0-HB,+,A@3''7?'$!"4F-*=E8*-1%"0=256+<-85C"&E4%5/?$C6,81794./"-H%"9,'6E,;@>B;7E/2<%B"A*39?!#!@+"/&B);00-&>#H7$'@)6:3B%%@%C<-&2H@38>,&+.07/F=56=D@8="3$*#5E5
@r7573
CCATGGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATA
+
#<?*.?=&%*'@07.AFH;0+.D/0?87/D3F='.)EHB;%@:E-3>
@r7574
GATNCAGNGAGCTCNATCGCTTCACGGACCTGCTGGGCAAAAATTTCCT
+
(&$!%*!")"+%'#+&!)#'%#$%"$$()&!&+%+$%$'(*$$)(#%'!
@r7575
TGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTA
+
H!88CEE0!G=G@:<6/D94A/@<8%C/:;$G09F7%)H%+G-3?>1+BGHG@?H3EB-;4,F"'+=G+FB
@r7576
CACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGNGCTCAAAGCGCCGC
+
7@D,;?D7?G;,4-@.H7B:4?8A653>BA-,6$&<D4C/8DFEB%EF*20>?#7&H#6/E>-8)GD45(H29GD1F=1G76D-4:=?=("D
@r7577
TCCAGATCTGGAAATTNCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATC
+
(!)+$"!!#(#+!)!%%)(&%(')&"%!++!##)+&%&%"+%"'*(+!((++*)%!"%*##&)+$!!"%*$$#($'$#+""!*+)(+'+'
@r7578
CGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCNACANTACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCANCGCACCGTTCATNNGTAC
+
$6#C+:19=H:A$763D"9<+8@=9'DF-?6#1&#?>5*7:#(94H:F/0;.=</;.$C8&'&.DA(3'?C>7$&C>D$;#,+B0(E??+9E#3;B#4G-D$#A!A+$<H=>
@r7579
CTGGCGCTGAATAACGTCATGTCNGAGCAGAAAAAGACCTGGG
+
&(%(*G",%6!&$7C$2)8B#78DF3@-.C-<)9@7D*.+B<,
@r7580
AGAAAAAAAACCGACTTTAGAAATATAAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGT
+
DEA<,*"HH(!1B462/)G*&;&251H8BH53>$>/8="FE"$16D1&"""?4((6FE77A=)<2,%0BG<;/B"
@r7581
CAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGNAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTNTTGCTGAACTGTGTTGATACATCAACTGCACCTGATATTGAGTGGCTTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGA
+
F0!2!#%?<7%A..$.')@&DD-A'@15B$#"1,C0=B0+#E(5A=0$*H)@9"H"G5)9A2=G''>E981:=;3&A=>4>0',=(%1@<4#D#,'.5A5?,2#25";D8/G3<31<25A)@F(/DA.$/#)<.3:=.-?C"CCB9H"<@1G<4=8<76:7#(BA'D-?;B!,'!!)H%%"=5;(?F8)";1235C%-*'CAA,005<!C<$25*G&:-2;5"D#:18(5>C&.>'-&B*D9986<F3%$$2G
@r7582
AAAGTTAAAGACCTGACGCCCGGTGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGC
+
)H63'!/)B.F;5%$9%$@>!2-8(,B8,97?$(1?&!761D0533EF!,AFC?#/;E?+A>,71168&%6<0,!0/#DH63B>C8!@,.?/984;GD2BDF*&&!@D%?<-5D
@r7583
CNNANNNTCCNCTNCCGGANTAAACCNGGNAANANTCNCNNNN
+
"#"#"$""!#"##"$$""!!!##$""#$#!$$###$!##!##!
@r7584
TTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGANAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTG
+
9/??'70"0"39".<0F(42"/+?4&%-.5G@?3/,:+B9/+-D53"-,/;G#0A#G*H>5#G!:-:<31B!+%"5-=5'F6:,$64:>.7?>')?G<;0:)60<F<:B05%)!F&67@#<;,9&=A86F$;%>.F>?9(6+"C.$""&:.?/!A?B0!.*1/230.B.F>$#D#07,2:'?H4G2.+*B-3,+?3"13A&0H#H
@r7585
NNGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACNGGCAAATCCCCCCGGTTAACTTTGATTAT
+
*!F&<3>-A4,79*.#;4>BA7=0F0<31#G>;A-4@?084*%G1G->=A17-E'+)2@-?+';97%B@C%-
@r7586
CTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCAC
+
:-DD"#%)3301$$%0"9/68';AG41?4!;C4(,A)#>E2B<#"B
@r7587
CGTTACGCGCCACCTCTTCCACCATCAGTTCNAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCAT
+
?"742,)H;"3:?F@&$3($AA74H,?.+4*0!94*@$*AE21,+7F);)0=,+'=?CG87+0(20"G@4"H!;?=H*+%D6/;'/2))1
@r7588
AGATTAAGGAGCGTGGCGNTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGC
+
<;ED986-(8=/,3'2:)E1&8%#$0*D6H;6!E51845%.:78&F0E:F:#8)C>.?ED.>H!F+341EC@D3--D+H3.,;/*CE(%G--"00AC'D0$'-?#9,H94*-'0=;5
@r7589
CAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCNCCCAGGTGGTGAACGGGCTGTACGCTGTCCAGA
+
*DBE).8=B'*?C/!56H?(7997-;)-1'G/7+29!*6,&%%G@:87+E4'"899;)51*41.1"01B<-4<8;=B+,C*C:59>>BB4B69AEA&*++!24@H>(B:.13F'G53&7)=A=*)A50GA9<
@r7590
TTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGATGNTAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCG
+
A#/"<'$/D.('?<3B?55=(,##9#(@?/?!<""#F0,F;=8%";,$<F<(.8)77*233H44<C06&%5#'1D?B%-9*8=1$D:DG.-/34"169+/)'<@-?,:#-6.9.E7:F7D2#'B/?/?.)%B&#,*";)<!F/5'5E02,G3E,2!F=AB!>8&.<'-1;/>'E13?;5#C#
@r7591
NGTGGTNAGNNCNNNNCCTCAAGNNNNNANNNTGNNGCNTNNTTCTNANCAGGNNNGGNNTNNNTANGNNGNCNNC
+
!#!##$!#$"!$!"#$!"$#""$#!$#$$$"$"##"#!"##!!##!"$#$$$$#!!"$!$#$!"!#!"!!#!!!!!
@r7592
ANATCGGTAGTTATTGTCTATGCCCTNAGTTTTGTGGAGCTTGGAGCTTTGT
+
+"'%*+%#)"'$"+**"!)'"#!((+&&+!!%#++&((%#*"(&)!+'+$*&
@r7593
AGTCAAGAATNCCAAAGGGATANTTTCGATCGCTTGTTTCAGTTTCGTTTAGAGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTAGACAATGCTTTTATATTGGACTCAAGAATGCTGCC
+
%++(*%)$'$'+'('+!)%'*#%*#"('#!'+'"')'$%+!!)#!'#%#(('"#&%#&%*#)""&$%(+)$#)"!'*#('&'!!!')&*'%"(&)!*+'"+)%*+(+*!&%&++!$%'"(!&'!$$"*))#(#%*#'&)"
@r7594
GACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAANGATGCCGCCAGCCTGACTGAAC
+
D:>GE;DF1H!7B";(,("A349?<5/=)(?/H390!<8%:H%,F#9/@E49.<(G40/0G8-=!$>9
@r7595
NTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGNTGAATTAAGCGAATACCGGAAGCAGAACCGAATCACCAAATGCGTACAGGCGTCATCGCNGCCCAGCAACAGCACAACC
+
"&"+*'&#((+%(!+(!&$)*$+++#(*&*!#'#+()&$%*"!+!)(&%)"!!'%()!'$&%*!!%!$$!*$!'"&**$+#*)#'+!)+$**$)'&*!"&++'"*#*)'(%)+%%&(%')'"'#'
@r7596
GCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGNACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGGCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCNTTCAGGCGGCGGGTCTGGTCATCAAACCCT
+
A6;=G%(@9G*.:4=F0!7<):';#2A@1>A$6-H@6-"<B3?!@)D/3?#&!:@@<4)-DD7./+;$14;E$.;$:1"*@26;HG#E@<B4/B?"*&4)/,2(@(4@A&!7!';$>(EB:729=&G0%4E656&(?:8F3;C>.E;!DF5'<>H2%"<03<?@.9:4HF&5&"';H1198(;%D3?#0%!D47G;@5HDAH1#4.G9G&%E$#4@B/D+/<<D
@r7597
AGCNANTNGAGCNTCNTTTTNAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACAT
+
$#*!#('$#''*"')+'(!(%$#("%*+%'&"&&''&%(#%"&"$$*+')(!!)&%)&!#!$+)!*++%#(()"
@r7598
NTTAGATGGTATTAGCGACCTGTAACAGAGCATGAGCGCAAGGTGATTTTTGTCTTCTTGCGCTANTTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAG
+
!)'$+#+""'*+#$!+"*&)*+"*$&##"'&#+%+$#)'%)"+%#)'($&#(%$$*$%!#!!#!"'')$++&*)))')$)%&'$#(+%)"('%)%%($&+%!#$#"+#+*'$*&$'#*"#&$%+'$%(%'&#"*$*'!(!(!)+'!%(#&#+*#'(#"($+'"+'$*
@r7599
CAGAGTGAATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTG
+
@?*38578$,"#)D(<*&*2=:!((H2>(#9*&;>8#<3&,=91,G<4/);<-A'A7F)H
@r7600
NANTNATAGCTAAGGCATGTAATAATTCGTAANCTTTTAGCGTATTAGCGACNCATCGTCTTACTGATTTAATAATAGATGATTCAGTTAAATATGAGGGTAATTTCTTTTGTGCAAGTCTGAC
+
%"(*%+&(*)#!'"&("""%**"(!$"(!$"&"!(+#"'((#"+')&'"%#+##$$'*)#*+)$$'&($)#$)(*"("'"%$&!$#*%(+$*#!#!$+"))('!%$+##+!+*"$'!*'%#%#*
@r7601
GAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCG
+
#)$+*($+*%#$&)#)%#!)%!))+*"$!'&#%&$"+(%)*)"*)*%"$)'"+!(*##!#+
@r7602
NGNTTNGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGT
+
!(%**&'+'%($('%('!)%!+$'*"*(*"!#'"+$%%('*$$*+)&')&"
@r7603
CGCTGATTCGTGGAACAGATACTNTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCANTTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAGTTCGAATATTGGTTA
+
6.E?8,7#1/!$'F2D#07=45G))/'=*324,C&?G;>&73>6<14-&%))@";H5277D:/@GCC0<?"$@/8&&"9%;@"'&*1*,-@9%A68AC/.5C%A43H@!-9C2@;F?(?C/G6.$;5H2G"&';1.%2!)"E"E!8+.A@-*#H<4+H8(+36G*);5&7)7)B=<#%'9H%7>C4<$H8);E%>?"&A&'533(9?HG-2.;+A+".F=:6B6%((
@r7604
ACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCA
+
/01?;?E0-&FFA4;%2"EG@16?@1":9<?72*/2B?6/(#GB,",$#F-B0*#G>(9888F"6B-#)+5,A./A?
@r7605
TTTGGTAAAGCCGGCCAGGCATAGCTTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCT
+
()3HG,0;,(#=2>'*".0G+(,-$/6964GB#9>1:&-<C26E'H3CG@H5%;-?;.:G8$:*'(
@r7606
TNTCTGNTGTTCGNCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGANTTATCCGGTGATGAG
+
"!%!&&(('&"(""+''+!$*%+*'&*%$)")!&()")$('%#$('(()"**(+&+%"!!#!)")!!%*'"+*)*)"""$+!++)'&"*%%+!"$)(+%$'"!!'%)'*!*+%&!)$'"#+)$'#%!'%*'')#+$!+*$%(%&'#"%!(*")'*&#!!%&!$")!%)!#%$+!$)''"(+)&'#$$+**!!$&)+""(*)&
@r7607
GAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTTA
+
B2240);C"!D%%?:)B---57#=8+(:$+$&*3*16F5(01A/"@BCA
@r7608
ATTGATTTTTATNAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGG
+
H1=>4-/*?07*.?G0C:A%=#$0:;'19G75"7=DG70*DG.2#>@B.1D>=';5A+18);=<!9,3FE(>$!=F<;*F3(*8%(-64?H/2#?$)'4!#/!69F<90!%?B/6)*'7E%'(+@CG#7.#FAE;(9AH7HF'5.'>0&9H%=35A*>C&
@r7609
AGATCCAGACTGGACTGCGACCGGGCAGGGGCANAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTTATGAAGGCGATACCCGTGCCTATAAAATCCGCTTNCCGAACGGC
+
=6,,02D)4H);0B!*=.E=5%#.B/<B=,1281:&*2D*/>A3-,#'C.*-4-B97&#1=5C0-)F567"F0*#/%/3!G+1"89<F?93:-*2F(2H;*=&&-,<!9(/2F*DG04H85,-8*0@=79(F"<GG//?$8/A*E.))217#1!)'>
@r7610
ATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTNACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGNACTCCAGAGAAGCACAA
+
A6A8'28%,CH$78$DA<4'4<"G!.B%!34*E5H-"8E):3'*%5FH&B5>#8F,AFC=A>F7?A+.2*&B0@D3B:A#%?C(1H2:C*B<G&=-.8=B&,;3F@#A<.@:</>*##:133??'D;9*!)
@r7611
NNNCNGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTA
+
&%#)%+#'*+%"#)+)"&)+)'&+%)"+"()%"(+)$%++!#+(+)*+)'$%)+&%%)%&*$'%"$)
@r7612
TTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGNCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAG
+
;'FB/@:@5=.5@B;=G'BEG#901,G>(4@&H<"?==6/%=!,E!'+#=*08:$:A3)+8!G:>5=1(E!#;F6>.?1+9:-<,9C8H=6A(&88<$+CCC-B9C!A68E3,":*.G)&H)"?.8//D#6GF.!*@E5,!>,%@::;2,&A'!F4<<8GA21
@r7613
GANTGAATTTCGCGTCGTNTACACAGCGATGCGAGAGTCTGTAGNGTCAGATGATGACCGTACTCAAACATCGGGTAGAGTATTATCT
+
''#+#$"'+$'#'"&#'#'!'%%)%*!'$(*#'%'!**!*('%!'*)#!++*(*%!$'(')$!*#+%+"'!"$")%(*$(%++#'!$'
@r7614
TCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTNCGT
+
@"?E:5%:$;.=;1D%B&-:C*F3E,)1*;C2:61ED/=(-&C100G1:/A:&',B</#6"H=$8@G1-8#/<.'<037G3H-04A.&4HF.,>$9019'A:@
@r7615
CGCGTCCGTGGTGGCACAGAGTACGGCAGACGNGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCG
+
.#AG3#,"H9(F:(1HH%%5B<F1H48E:(44+G.!;8/=3D*"EEAC8&,EC:6,>=(93B>D8("!8B108/&.<5B#.F>
@r7616
CTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACATGGTGCCAGCGACGGAGGGCGGGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTT
+
D'A!8/>9%F>4#*6E:.1@=9B*D!F;2+:,133+'719)?7)8>9?!1."0%F-;70@G==#3%<;21@!2*0$+93!%B-<+:69!966:F#=B5$"A:E!=E7!96##2
@r7617
CCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACNCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTT
+
.FG3.8;C5C/GG$7,,.&F97<@.=F39B#?G;</3!1:<@869<&B9'A%')5A87E*/#85CB/*=C:58+5?382E00.F*A<C@,*#AH436+$;
@r7618
TGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACA
+
H&:FBEEC*?#FHH'>+>,5#A"#D@GB*H:F35'30=A9,E%-0=;C
@r7619
GGTCNTGGAACCCACCGAGTGAAAGTGTGGATNCAGCCCTGTTGCCCAACTTTACCCGTGGNAATGCGCGCGCAGACGATCTGGTACGGAATAACGGCTATGCCGC
+
;=/C8'9A>:1E1@?.C.)'1<#6G$+-CB5&!1DH;7@(98'0DF$.).6;0<>0@8%?72F2B:&+7ECC8A:6!(E(EH(E/%<"B=;>$.=*%6@-06"D"3
@r7620
CATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCNCA
+
+'#$%++>99&DE?C"F1"=001*G2).=?03F/,=;D.F?5E(76H@1;2@%H6;>&*:A(="E:G"H<!
@r7621
CGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACA
+
>AG0G("5G<6+??;FE1G%+C6EG&#$;;81!<D51*&8E0)G?7#AAC'&,::29@;
@r7622
GCGGCGATGACGCCTGNACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTACTTCAGCACAAC
+
-2C526"B19-D0#@G)F#"966C/?C&2C*C3#BF>$85.<"%A&DGF61;?!;HG0CA6E>B=)(.4
@r7623
CAATCGTTTCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCAAAATATTTCGGTATTTGCTGCC
+
@?;4<732=0#5?(<%%G5A1/6?.892?**.3&C7$-#*5/@%).3/7#F-+/;!%C4;)0)"2(4@4?43+:FA36.)#+
@r7624
CGGGCATCATCCTCCGNCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGNTTCATC
+
<)/+4B6(BD6.H4'+.*F:A*HB25:"=>.3*+;4-?5#%/G94"9%.G>%7+'<FG2956(/-;B0<EB;"4C=?#:B9=1#2;HC$+#EH"-81=;(;%+@,'1HA-!":>D0D?*:'"E)H?'@<0(2@!!8:G4E5"<&H+=4#"%EHA*7,(<6<?)(16/
@r7625
TTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCNTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTAT
+
:D(1#=)6$7F@<51H/G(9&)+7.8@C527!(G6<7G,<;"H+?'4!?);H64H:?8C/+H%,.+H%4'"@0907"#$3AG%*.<8616A497@@=D/"=G"03F:.G466/;F><=+!<63?.-:;%?')CFAE-,!
@r7626
GCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCG
+
(G3@$33>H-?;006"1&-!A#"4'.3D8%/*=89:AH:88EB>)&9;C$0
@r7627
AGCCNANTTTGCCAGTGCTCNTTNCGTTGTGCTGAATTAAGCGAATA
+
'('(!""(&"%&$'&%))*#(')!$&"+$$#)&+#&)'!&&#*!+%#
@r7628
ATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGG
+
3@05DC,-(%>AA,G<F'94,F'758!@A458>G$B45/0'619#1
@r7629
TGCTCTGCTTATAGCAATTTCAAGCGACTTAAATTCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGNTGGTAGCGAAGGAATAAGAATTACCGATATCGAGACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCANTCGAGGCGTTTT
+
*49,@+B0H&F3?F@.F90/>!>&('?5$'F&4?HD#F"'+2=4%5E$>$D6)'70.E%<>$.%*#C:<=AC,?F847D3(/7E-:<A9<6-4-H!B%-!AB>E;E8D#%&3/4611*F+64#;B"1<##!:'+-?:F014A2A78=*+>?14.@#H5@-/C#CC:<A7.<,7@A"?%C0E'?%##5$55>A'C':'78"F41(6G*E-&;B'*D;4@:,,<:G<:A"%
@r7630
ACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGNTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGTAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGG
+
+($%&#"+"'+)$(#$+"*%*+*#$**'&%'"))!+#''("#%$'#%!'*+")"'++'&#(#*)"(+(+##!%+!&!**%&+#('$$!#*'*"#)%'&(#&)$&$&+&'##"%#'"&&*&!!(#)!*)+*+"(#*+"*)!+")*('%+$&%'%!%(%$""(*""$!"!)"*%$+(#$&$'%(%+#%&($#$'*%+''(("'"%''$'+%!$%+%%('(!)($$*(%)'(+*!&(&$)%&+#'!$
@r7631
TGTACTTTTCATCCCGCTCAATCACGACATAATGCNGGCCTTCACGCTTCATACNC
+
<.6*DC@>>.$0%-5D.H7%6A"E$,#$,C:6#.44C-A*1?>.8-D81+!4E5:B
@r7632
CAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTG
+
>C$6'?+G*G/%"!(&.24G,;.+)?B2'C7#?H=?<<78"=H;;<*BE$A:EA0EA$)>"
@r7633
TATCCACCTCAACCGGATGGAAGGCTTCACCGGTCATGGTGT
+
E49.?)-A%+7&G'*%@H?&+:$*@7#'<;7HB98%88=1FB
@r7634
AGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCAC
+
-91C.&C+4B+*1*$G,F-B"3&16360H%5/5"BF9<F0!?>2>F.#,.!8/0FGF@*$H-&F2.+D"3C
@r7635
ATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGNTATGGTGATTAAGAAACAGGCGCT
+
4/0D:6@$!!$974&-ED"?B,8!?39((%5'/;B@894BC7>!!-;E9):7++FD*;-
@r7636
ATTCAGAAAATGNTTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCT
+
E,!(<;6-7(1!6E#E7%17@,?E27($(('7-@/2:A.<',-!6E;#980H&,.,;9%/;?;!&,)(
@r7637
NTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCT
+
"EF-G0718?G+F$)E$=/+0E43-(-0-CE(.+4!=@F!F54!
@r7638
TTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTANTTTCTGACCGTAC
+
%/0=',1%AHAC"-/G3),1G=*C@/%6B?E9D1D$-<H3#>5A%)(@@9&/G;,6+3391)@CG$<?<&B:*F?F'F:$CCBG:3G,%*
@r7639
GGNCGCAAANGNAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGA
+
&)##%()*%!&!'+'%!"!(#(#'"()*(#%"*)$+"$%#!*%"$'"##"''+("!"#"!$"+!($#&#&&''!!"&%)
@r7640
NNNGCGATGGCTCGCNAGTTCCATAACGTGTCGGCGGAGCAGATTGCNTATGTT
+
$!#(+#&'%#%(*!##("()'"(++$'!*"*%"(%+++#'#$#"&((###)&!$
@r7641
NCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGANCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATGACCCGCANCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCAC
+
!6@"/(;+F7&#2%$>745.@F<B$9%E?=)B>2BDDD-#H&,F4,0#HH(>%8G$#2%+("&0*4E<H2:E,B!B3@82BCA)GD6/3(@>@*FG)?<"G$>H8?D7*:"0D/2?&!?@G<01&,C8+:D.$;EC7+',GG#$''H!/59?G&9E$3?72:A0$3.#C2$3G54%848*(DB*FH9+7)E<9B4<'43>5(5AB*6!4F$D@,,1244@4=;.D.?>!A@%%4B0#<8+D40FD%>4*6>9F%&*$!G#33/G2)10D0:B0/"<<CD<!9H
@r7642
GATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCC
+
"&'++*&#"*+&+$&')#*%'!(%'&)"*$*!)$&&+(+$#'(*+&#"&&(&++*)
@r7643
GTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAANGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCT
+
B(2H>D%H#-/,EG,.6;11;19FAD5,.2+E2';H&#(;;,38#1,)2/F4&3<$B=8@=*C)E2%HG1>);EC7=@#/1D3<@*'C;(!2!/-)+/FH,>B(/,>!:,3#**!0-3&E(
@r7644
TCATTAAGGGCTTCGCACAAAACCATAGATTGCTCTTCTGT
+
;*:B@3A&,=*!GB:#?%7D=:8$B59H'*7-!>G6CGA@;
@r7645
AGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCAGTTANACNTTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCA
+
!,).C*H=<.&!46806C>+C8D$E?9<F%.:"D"A1D2?.=?#"',+5"$.H'@F@68AF&3&8;!5<@@E0!20>BAC"$GE79=>:(@B@<&5H$8<DHAC3*0A96
@r7646
CNGNCTCTTCNNANTATNCGCTGTGCTCAACAGACGTTTACNGTT
+
*#'&*$$%!)"$(#)("!")!+%")%+"!))$&#!$)"*#*)!("
@r7647
TTCATCATAACCCGCCACATCCACAGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAAC
+
480C<'E389>3B0"4/(*H4(A0A>F:)H,98B'7-:AGC5*.6"FFCD;6<<5>//C#1%2D(?;=)'(+>3:DE>A/"B98AE5+0?>@
@r7648
CGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCANACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAA
+
C8*/&==,&E<?81?5&A"#3D9"BD('@3@1):G&5&B8DA7F:E<$,AC)H%$>B).=;(66;=6BE+"?C&::<;B$'/9=!8@B+;A+%(*1&*,056(@&DA3?089B!.*/$1&30FF8
@r7649
ATTATGTATTAAAGTTAGAGTTGTGGCTTGGCTNTGCNAACA
+
:5B@4%01/<3*2,#)F<(FH@*2@C,DB:>FD2.@5C7H""
@r7650
GGGCCAAAGCGGACACCTCCGGCAAGCCCTGCAGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTTAGCAGACTGAAA
+
E'!G'2E,;+-4@H7";>)&C6A#*DF'1E8*$/2",2,3B?G"?C43H2>A1G?*!D.)24*G2B1G96>98D8??H+H!&G;%-+,!E9-.1%0B&"
@r7651
CAGTTACATGAGACTCTACCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAG
+
$E#C)B:(=2F#;D6.,E7B,+%6D,"EG+!(1>,.+;9&:E(B>D",/,?1#@.?0D.7=>2E*&
@r7652
TTCGGTATGGCTGCNTTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACA
+
-&9-D"$;!>AF$@@CH&1H$5G4@F%F.$(%.C<E>/'16EA0:#(:'5=:9G@:+53<,HH5D$9/"D/88)6;-79&.F7'H!7?E."<%4503;*BB2).36DFF71-6@'D.892@(B$6*//G&)6#B%#@("AAF4':9=9!58":>G7G"6<4=,583"7!C#=<B0D=2?E?&?@7F,#*D')9:@C3H4*4.;B3!6E,A>&,;@5;C',+16>6/*,%7+4:C
@r7653
AATTAATGTTTGNATGTGATAACCGTCCTTTAANAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTANCTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACANTTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCANCAAATAAAGAGTCGAATGATGTTGG
+
.H)-/5CD@BG+>#<=>@<+(&,#)<1<"1+89D9E$%"*$05A9-ABH?185)4-.99=$*C2'+"<@-+"$?!%.04B)6?2*H".4&B85H-"@H@=82"1)27/@F/2:7'9<HF!G=C-!="!.%?9$H(%?=%A=+3*%$B7F3H@!D*(8G.9?;75,<H',>,D@.(A.EA1B(!3A-!($4+403A$4%">=@6/H2@D=;4G4/&G66>>1('.<A9>@B5'C1A?3,5#"E-.)@4G@9/)'0-
@r7654
TGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCT
+
@?)((3"2F%G*!-"#D;,A%5F3!4;.9<F4E60*':-)C&?#?3&48,GG(5%#,92
@r7655
CAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCNTCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGT
+
>D+40G&HH+(-%C+BE?*&@3&"-GCH$.1,;@FFB<A(05=@H)2F&*#F=E*%/*%+6?DH6%8(,/8(-G"7G/82$2GF;,*80$=;.37-E%70%13."7!913B>5/#.(>$*5<$5,7#<&9H5(#1418,/*C;<"7(9<-FG/C%>(59G,F+:.!/C0&%AG+579AC?"(1BE-/3H-%-"@?=C0'
@r7656
ACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGTACGGTCGATGTGTTCCGTGGCTGA
+
G/%;"609<A(1H;D$!$(<:$&B>47'>FB00%0,8;65*+"3".0C7+@3$?$'=#0+H'F/26*698A>9'F#;&BC=HAC=5&*"D&,9@'EE;+!</(A;6EGG1????::'1HE(!C
@r7657
NAAAGGAGGTTNAGGTNGTAGTTNCTGAAACGAACAGAAAAGCCCACTGGACAGT
+
!$'&&%&*)%$!(&$("***$*!))"+)&*#&(!**&!+)&#*+*&&#$%!)$)(
@r7658
GACTCTCTTTCNGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTAT
+
878;,?&&=>57@;>+1&(:E?%$)9D=#0'G075.EA5F1=+8&3E3!6A/;6A)7+,81$4&)A75
@r7659
GACGGTAATTTCNGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACNTTGCCTGCAGCAACGCCGTTCACGGTGAT
+
0)&?%EE*185)E(%*2H7:52FHH?EE=+8=@?C(4".7+F)(!%G+.?H!HA!G)=04.A0H</&E8"<$?'D*E"0+1%/=1!D?4%
@r7660
CTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCG
+
<#:9/0%-990HHG9)3/&"FB!1<%&:+!)@EG#0A&2:4$C9'$H./
@r7661
TCTGGCGTCCACTGCATGTTATGCCGCGTTCNCCNGTCTTGCTGTACCATGTGCGC
+
&63D7:9G,2/H"388.4"6G/&H6<*":?C>H"/-H;F(41F8+(3@,4093(4!
@r7662
TTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGANTCATAGTGACTGCATATGTCGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATNGATATTTATATCATTTTACATTTCTCGTTCA
+
2(G69'F2:<&&255@310:=#F(7E/6##B?@9#+2;8B#C"#*79F',GD--<%1D+G<7??DF1!<9=%#9B$-)5;69D.F49?7""$4@/.9>?:HGFD):,"'8<3+$05H9#E1+!6?B10/C*/%:C:104D-2+&8;=",03@F9A
@r7663
TTTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAA
+
')A7H$%&@BC&:H:+%7=$;,=#*G($)&,9+$CH'H5B;,;E$
@r7664
ATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGGTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGAT
+
=&/>?D>;69?<8&1;>.'"4D?(/>3F(C>))9,C>64@(CC)"3FF%F=F(31-G;A('F*%06$-!D&.,H209=3<CD466"ADF@6800%2BHG/E:'"58;(9;-!$7>
@r7665
ACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCANTGGCTGC
+
<4?4<%'6::?(*G0$9H-4%&$".D=):/6&3<637.#E!E)?<2;?H,=/$-=;81!1*7-7'D
@r7666
AGTCCCAGATACCGCTGTATTNCCGCATCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGNACTGCTCCGAGTC
+
#3*0BF414!$$"<;C.E&'2DA@@,"5(?)%(=39,5+E*7%9$E#'46'4$@'H-E>7@EA!FG<;09+@>B,1547!6=;DD!*:FF#H'8''E/':+BH/H;:A982/&B)F*;
@r7667
TGAATATCTCCGGTGAGCCGGAGGCTATNTCCGTATGTCGCCGGAAGACTGGCTGC
+
5.';B/<D/,,C#'4=:93-#8=-0?@'%$C9">8&'G-%:4;6C*$F48D7@?;0
@r7668
TCAGCCCTGCCGCGTGCCCGGCTCTGGACANGACCAGCATACGATCTGCCGTCAGTCCCGCCTGCTTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGCGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTNCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGGCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTA
+
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
@r7669
GGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAATGATTTGCCGTGGTGGCTGGTCT
+
<<6;ABC,1.F-3A9*;=%4:57#A/;-=%-&+074?)5>H*DH5$7,.4=*:02D5,8204(@9H$;#/H2<")G"%9>F(F$BAF79E@%C=5*<F2BA,?&C7>43*2<5C"#3D+''%:,20
@r7670
GNCANNNTNAAACATCTGTNCGGGGATGTATTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCNGGTCGAGATTTGGTTTGNTGGCTGTCACGCCTGCCTGTTGCTTGTCACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAG
+
$&$%#!!$!"'$+&'")")%)%'*&%$%)+!*'())!$%'*(++!!+!''')!))!&(')(#))"$%&*())&++&!!+#!'#'('!''&*)+!(!+!)'*#+"**+#!!((++"!)")+)()$(&&"&++!!)%'*'!%#'#(%$))!)")%%+("+&!!$"#+$"$!*##***(%&*(*#"$+)+"&))!)"))"((!!+*'
@r7671
GCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTNTGCGGNTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCG
+
:>B)0"3)0@500*6'''H)#/7<0.>=3==7A9A"81H43$7>#:53@9*594AA7->F/B?'0,,@@%2.64'70,1H$$2G&E:3
@r7672
AATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGT
+
0-.CG+'(@G-2#%DF9&@?<B,,1<6!1HH3A,="@;,FF(&"#6"70D0;)(#F6A//9F:+CEE'@@4>&@&+3)G9$&G&09H+09/7"0;/%"$)A#.''81FABDF@'
@r7673
NTNNNACGTNCNTACTCNNTNATCGCGNTNATCNCGCCNGTATCCCAG
+
!'!'!!%&)$)$!#'#)")%'($'%"&%"!'#'#'+&+&"(+(!%+!%
@r7674
NATTGCGGAACTTGTACAACCGCTCAGGCATNTGCTGCATTTATCCTTCGTNATATCGGACGT
+
!=8.1>1&+7!A;!+83:,:@G-"4=A(?36#A,G7@E7F&=>&65@-C6)'C'.9EB-3B"3
@r7675
NCTGTGAGCTGCATAACGCCAAAAAATATATGTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAANATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAGCTAACTCTTCTGTCGAAGTGATATTTTNAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGANNATTTGCTTATGGAGTAATCTTTTAATTNTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCAATGGATTGTTTATTTGTAAGGCGTNAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCC
+
!:)E>F(1-%5?H3D%'G($%F@42:/F1HD-*CDF;:H,9D97&9<-"F*7@&=@<8>FFD7':.H4%92*9=A26!3,$.>8=A645HG7$.B$/.77@6*);AH9+E+"G">?C+*&<GB&/%C;)EC-H3;=*"'8=&9E#6G32HF!D*F&7E:8=;@A8B=1&G'!6C9'C!(5:DEB<<%D'G=GD5*.:9B038/<2;774;BA3B.1A%B5>4)%70-=4BGA#82!5%(,6'CC$B6?;/*:-5(C#E9$5&),<'#:6/8A",8,+;001:F59;/$1@$42DB5>-C:9::HE=A01!GD4.CF.#+8'5,#&'F9:B)C@4#00"&47F,@$@13+13;;4$)#.*GG:#=*!H9GG*1%(5?:DG90'5>?86"+6B6GE!$%@0C.9:>24%F#-;&"?E9#(9GD:G8E6$!&F<7E$**-D27B@.0>$>G>5A<.06-".F"F:3,($2"!#1G*F!C*A(0A:=#E=H
@r7676
TTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTCCTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGNAGTGATGTCAAA
+
<F8=751(=21G+9/(!D62,.#,764A1$4#9CGG&0G4/354(7)7;E@9C"=G$7>.(F!E@/8=.>5H</'*7=#&8&H!;,BB(1A(+:,<&>%"<=2()"FD>BC6,5;++)7;!CD%:C%:<0@-EFA-):$@?7:/>8E%"?&)HD(B+E8DBG=16G63*A@/2C>'7A1$+/<5$F'C'-#G&-?&+BA'?900:;$4&$=73"#H7>=<7),%&4-#:23";B5&74;>>3,9'1&B:#:A(;
@r7677
GGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAA
+
(H98H6F4=<@:,$=5!AE3@)2$4,6F3/DF,(;*62DD).?4(
@r7678
NNTCCNTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCG
+
!%(("#+*&&$*)'!)'#%$%!)%)'!("##''!*&*$!$%*"
@r7679
TGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTTACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATNCGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCC
+
$/)9*%/('"$3EC'F26,0&%;HDB15C-"1/-0B7'7%,56@C3B@-7'EC>+D?<F*40/A!'FH5*1":H)?$7FC.B8&B/HH:0)C,;"7G;*B@8'%&<8@.C!$%/FFA+5*(B5.4.8*C%-6$*B?,#B""7*@(*2@A60BC-+)<(;--E;/=41G30+D4;'C)F.;-EG?/:8"'**02++#(6D/'6A(F*$#3;8"BD"4*D-=#975&<98+#385B)"8@"@+FH6$&33B%@?#EH6*30;H5>A7?"5/
@r7680
ACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTAT
+
G8$="AE*/!%(*D+H'5!4!377+D!B<G0.B-6<+D<7(,0,''99*EA@,"+H5.E!,A
@r7681
TTGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTC
+
-@%GB1C+0A%&,5'#<;B<FB,67F'H'B>G=0>55H(27>)&
@r7682
ANNNTTATTCNGGNGCANATCTGACCAAGCGACCGTTTAAA
+
''!"*'')')"('!)#$(+'(#))#*#%"+"##+)('&)""
@r7683
GACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAG
+
6%/)(27-C=$%.4,4+E!E&H/=0F)0H0/!(!:D9G@$@7>(<.F&/.=#E9=:H.H*)6-**5D6?/<D
@r7684
NTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCAC
+
%12A-5=4%-$;4+%D;D!+%27(7*?!1H3&7!:*?-E"D)$FG>*"7?9FF)"D:7<!H"B0+=,3'%:D-)<C2-%B*<E,,$&+?)4>C6%,=?D2-@$63&E-B!9#=089$-A#E$7D?1%D=#,FE")C4$#8.><?,*5;*@4$DA$6?H3*#*#-B709-FG
@r7685
AGANCNNAANNAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCG
+
'%"!'%"((#+!##+##""+'!+)"*+)(!%#(#*%#+!++(%'"''!&!'&(*
@r7686
GTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTATG
+
@+=@<2&8?59'/->06G(E$H378/D01.A/<D!4E;!8@@3>0<(:::=7'@<5-"6$72+)'3)3@2@3%BD*F/+!17C?$CB"!G>((H&$
@r7687
TCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATT
+
128:!24@(H78EG(&E$:G+<49!CH1H3C><!>'/DBE.3@4!0585%"
@r7688
GTGGNGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTG
+
')'$"+%)$"#+)"+*)$*")%**&'&*"**!*$&%$)+*!$*
@r7689
TTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTA
+
*/<'73HG*72,DA!:,9E4A1+;A/.")"G#-?H?'>8>:""9#5#34E'D7:+>>/C%18"7"@08D""B*G*?#,5A<+-A*@'"6:1);3,!0#C=<*"346&D,:F+;B
@r7690
AGCAGTCTGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTGTTCGGGAAGTGAACGGCACCGGGAAGC
+
+*#"!*++*#*%++&))'*!#%(*#')#"&+#)&%))"%!(&&!&%(!#$+$'"#%&%''))%++&&+&("(!
@r7691
GAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCAAGGTATTCAAGAACNTCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTT
+
!H"G+'+:)2=.&#7"($C()9;F*AF3?7H8@$C&%B0E=G8054.?5H&@C+=G38/&H.:E%;)F'.76(==E2'A>E;;/<+*DAH5.$$?9=D0A&A1(A(D8E7-+H4GA6B8$@B-;)9@/@G3D--GA/A?=?C%HF%:4E.A&--=".1;<?"+'#?;&4H)??1-EG.+DFFE:FH/:.E3A.A@A?D=-/AFE6>@D0
@r7692
CCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGGATGTTTTCATCGTTAACCGGAGTGANGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTC
+
A+:=BC1D0:41B6E#.GA>"B02=..4BH*!"C=)H;<8@5<$B,=F!6")FBH<"E0;(2G>>&47CH/C-@409E)3528CHC$8!=%*+-?/&>"B;71)3.05((=':B(E)+H&"@!>9/!G.$
@r7693
CATAAACACCTTCGTGATGTCTGCNTGGAGACAAGACACCGGAT
+
F++18+:4D3&')!7!.#A1(%$.<>G8A$-"@>%A=-50$&",
@r7694
GGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCAC
+
E'5,A3758A)>8!"<A&&/;)*)CF/72/'-A0!5;*)$53<
@r7695
ATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTNTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAGAGGTGATGCCAGCGATGCGCAG
+
-$*#4E0F*31<1<3>+;%6B0;>8G;H4'D'C&FD"B+3(2B:.'(>*>#67C3E!4+C,6A*5>*5)D2$0+AF-%@&0+1'-CED%%B-:*7D$HB2&#!B?;A$9%"=F/>&@3=<,4)"%#B978A$:*6!C?)
@r7696
NGGCCNTCTNACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAG
+
#*&'&)"(##+$(!#*"&"+#+'$#""&!+"$&+%"(&'!&$#!&"%)+&(!$&%"+'"#'&+)"+')+*(%)%!%$&
@r7697
NGGNCNNANCANNGNNNAGNCNNNNNTCNNNNANGNNANCNNNCATANNTNNTNTNGNNGTCGA
+
#$"#!#"$#$$#"#$!$"!#"!#!"!##!#!#!!$$!!#"!#!$$##!#!!!!"$"$"$"$!##
@r7698
NTNGNATGCCTNCTNTGNAGAGCATAAGCAGCGCANCACCCTTAT
+
!!'&$'%)$%%"#(!"$%$(+!)(!&&$"&(")%$!%"&#!&+%!
@r7699
NNNNCTNANNTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCANTACCGGAAAGAGAGTCA
+
!!!'(%"#&!+*&(!!$'*'$!%$$)**!&)&('#+""'"!+"$#+($%"'#%+"#++**!!*('+(+*$)*+$&!#%*(&%*"+#&$!)"'&&$*"!$$%''#++$#!%$)(%'())#+)+!%&+$"'*%&"'!)&"(')&($$%&)+'&!!#*
@r7700
CGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTT
+
-2:@2E5FC&5A)#HD(:+H9@C>-+>,G7-%,%C@+=&5@%*,
@r7701
TGNTGCCNTTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGACTTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTGTGCTGCGGTAAGTNGCATAAAAACCATTCTTCATAATTCNATCCATTTACTATGTTATGTTCTGAG
+
)"%&)"*"+)"&*)%!"")*"!++())##&+#))&'+##"+&(#*(%*)%#)*!*$&+)"&(&%'("#&!"$!)$))#"()!($)#$&$"+'%)*$&)*'(*"''%'!'!!(!$$'!*'')#(*!#+'#)%!"'!$&''!*+*'&+!'&%!$$+*(%+(*(#(+!)##$&'%()$#*%+*+$!'!$!(!)$$)!$%+&'*')*#($$)&(!#
@r7702
ATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTC
+
+*"(-,8A*$'8#HG2);=+AF,/54.?794!$4@*E4>E5@24A.193!*+B--F:(5D2*9
@r7703
GCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCG
+
CA+1E?/5=>(2C8A+#5>C2(<D=,<:(;5D5!*C*F4<(E/#23/D5&*?1-G8/B*CFH6#;;&;&F3&CC0"%":FB2>!=:&4';-HB,04:9,*7>,"#1'26*9D%95GD%*@-/CD?!/()>13(@D&-7:%5'."G)789=#F!)+7:($?88=7!F2B42-
@r7704
NGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGC
+
"BD(*8&1D8.71)*<D2.'D*=E58E@<&38.35.%26:;6:E(GHH!G$.((&+G*='&?=E8-
@r7705
CGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCC
+
;><;7FE:44EB:=C5?C+)7+H?0@91<145=":=-%"GHB*7"A7:5E1#>)-9"<F+".-0<;7A5248+7+/2C77$),;(E)F?;36-9D9&D:5>HAF$50(C<HC!-/4<A.GG39?!%G?
@r7706
TTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCAT
+
;'C6?"#%;E<81G1GE;;FGE8C@AA!#0<8>E<.D/6$BA,"
@r7707
AAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGNCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAAC
+
F&%DB"@#D@=3%1!.H1>4!27$E6H8&*5:,H=&CCHF;6#D;(33-02=">;=<B('<+G)?GG+!(>+0:-6C>=!B"!6716'>#A%<$+:#D@'6E$,5>*D,=8*6(%#B$D<7+(=G%3-DE1")H'>'BD2,2%"H.7?10C/'>5&:?->?;D)!(9%+?:?>46$C:.
@r7708
GCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCNGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGA
+
6=,D>::CHB%682"E<+8C'3;C4F,$6,;C'74=<:$/@!%$.,<<@)E@&D5"38'48<'#116G69-G?H6!!B<74<":4&/H!6;F!4CCF;"$0G4&D>*5F1C"C2.*3
@r7709
TGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGAACGGGCAGATA
+
HF2@G5><H9/-6!/,+A%(C:-(A6C@'A!CD;&7=,8B+?:)+$821A=11#F?@)#20D?.<$0CC,(%29?(G&6C78#A4<&&!);1A,+;$5+<H/-?4#23,*+*)<$?$A8GC%+52>9>#6%;*5!D*H.!76D270=<A='8
@r7710
GAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAACGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCA
+
#:CH=+0%*,>-(;3FG,)@2F/G0%=,A-2@!"?17#C!;G<(#):9>@=?,A"H+D.7"7426:40*068(9':B,B1?E5/EF$B("?.!;H6?E/&!&+#9%H&3A&-E)#@"4<"9"C=2$E!+,,2:4+/3@5<+<)
@r7711
AAGCCAGGTGATTTCTGCANAGCCACACTTGGGGGTGATGAGTTTACCTTCANGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAAT
+
%C%"'D->"832:B>%5<H0(,+.G<>A,G0"%6H::<H'B;&$0C6$&H.++6@3=(#9?3?.8"8+:DD:/,4$H%-/,@*2,17%94?BE$F18))/@9%+1A<>3$62=
@r7712
GTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATC
+
";,,E,.@3?HCC+<@@A+G1;*-5%/8.2'65FGBH!;2"02<!-<;=0A
@r7713
AAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGG
+
,7C"@01*C;2/C@:<9G*@0*"<5.3:6(B(0==';#)/10(./#8-$@G@,F5C7138;"7E1C&D2&)'2#0$2#2A2&!8!?<:7/0=F++$EA(2?#-;:6"8
@r7714
CAGATGCGCGCCATGCCCGATGACGCCAGAGGGAGTGTGTGCGTCGCTGCCNTTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCANTAAATTGCGGCGTGATTCGGCACTGATG
+
/?;,FH9F846A*%3(<C4@%&*/G9=9B;?$,<A@&E)3='$03$3.),+++?F#05/4+.G$-"F>8.=EF$D&)1:3?!.>8CC:?-F!E*2&,)GBC,C1%H:-H,H>F(&#2=4'A;9,,%89=+-=<<&48C!A%('#$!$,/+
@r7715
CATGTTCATCGTTCCTTAAAGACGCCGTTTAACNTGCCGATTGCCAGGCTAAAATGAGTCGGTGTGAAT
+
8?"6-!&C/?G@'H)0A%-<=?B4A4$9A*%F3?1@30*);',)&?9%<EBD21F<H!-9;$D<E@;/8
@r7716
GTTTTGGCANTATCAACCGCACGGCCTGTACCATGGCAATCTCTGCGTCT
+
E@&DE,7:H3+H?'(!8(!G/:E1<""'&"6G*;B0DF#FB?A=+"++45
@r7717
CAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGA
+
HF@*5E&%>+)"0(68;HG+96<A&4)C&!0:F-='>(9BC**,.1H)9:.H*94<1;B@<HC)&10!0B=!+ABG=+"E<&#
@r7718
AGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGANGGGAACCACCAAAGACGATGNNANGCATATGCATTTCATCGGC
+
59(63(=D&!?"E<FH9?G(>5#4,'%=41&B,;%414'.+4:6>$@H#$1(#-@=+H5=G#D&"2/5BD30?C/FC#H'!
@r7719
TTTTCCGGTTTAAGGCGTTTCCGTTCTTCNTCGTCATAACTTAATGTTTTTATTNAAAATACCCGCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGC
+
*+'+$"#&$+'(!%(()'("#*+()+)+)!)*!+#+'*+'"!!#*'++!*%+*&%)!+!"!+#%$'("+$(!$&$&'$$*%%$**!++"$"$*&$'*$'+*"**)'(((!&$#%*''*(!*(+$++"##%+%$&"+#''(*)")&&#)#%&$*%"'$%$(!#$$$"+++%&+
@r7720
NTGATGACGGACCACGACAGGCCCNCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCG
+
!+(")'&!+%+)'#"###'$'+'#')$"*"'#*+$#&+%!('$+')*&+$)#($&(&('&%(*#!%)&""$&'+&$#&'%#'"&&
@r7721
ATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAA
+
?84(FAB$.$"2-&("?*'2F+,4(=>-;2>!)6&<&%24F@G/
@r7722
NGGTGGCANATATGAAAATTGCAAACNCNNCNGNTATCNNNATNNCNNNTTNNNANGTA
+
!$"#$!""$"#"!""$"###$$##$!#""!!!#$"$!$!###!$#"#!!##"###!$"#
@r7723
GGCNGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAAT
+
$344+6,0#<#H/F0(52;#"G'0D3)05$+>H<G*-@2(A,@">=
@r7724
NTNTNCGTNTNNGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGNTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAANAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCC
+
*'"'$%)'#!#(+!*#'+*("*&!%))"!"*(!*")#)$%+%!*$&'$*"%*'")"%!+!$($'"%)")**$#"%*&$%*")#'!'($"#*"$"!#!&+$'")&"*%&!+$+&&"!&!(!!$&"++$$+!
@r7725
ACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGC
+
B-*)A$0CA@0,CE90.D%E-???)&F34,?H$02<94B.6,;C=4?1"@@8F?.625.35648<>B,
@r7726
GTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATC
+
?&G(,27?C$05>C:4=<-;9$H@:3>>;62?40>?3:1*#=D?637=&;%CB;EC3G&F1$2")=..32<4.0H:B,?70B<?H-BEH/,6F7B*8(B#
@r7727
TTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTG
+
$=*%3=#*<'$:G/A4,9FE9('D46/"-1.#+%2")@#:0$(F)GC;?>!)=&"3/F/(53GA(4C#F>15A+>.;F8B9.!2,+(?/1/#(-;?+.(1%()$&@#A8/74<E25'C7#.*B3464@D@-D(B1?FD&##0$'
@r7728
ACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCC
+
D*29F2);*1>&E:#H%+)2;8'.3"E519/$?3*+..-%B'"5CCH,('@ABA>GH0
@r7729
TCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGA
+
>'%(+*HBD+<);*E&$*H(4C?1*DB;@+A5@0-'B/%88&47;'4
@r7730
GTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCT
+
&DG#$/&0F.34>1%647!HC#0)'-&AF:'$)+>H@@47;B6@G)((=
@r7731
NANCGNNCNANAANNAGNTNNCTNAGNNNNCACNAAANNNGNCATNAANCGGNTTNTNANTTNGNTNNCAAATNNNATNCGTNNNNGNTNCAAACNNGNNNCNNGNTCTAAAAATNANTNNNCNNTTNCCANTTACNN
+
##!"$$$#!"$"$$"$!!""!$$$"#"!$"!"$##!#!#!$!!$!!##!###$#$#!$$""$#!$$"!$$"!$"!!!"!$$$#"#"!###!$$!$!!#""!$#"$!$"$$#$##$!$!"##"!"$$"#$##$$$""#$
@r7732
TGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAA
+
<&*$:##4-=%@>-6$3>'94:@;/9CCD(-<G4#-6=&;'"+,D*%2<!2/#65$#!-:84H'F(0>-/<*DA.(7+
@r7733
CGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTNGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACC
+
*'>07.)2$)E?AC@#%G+B.3H2.!G;DB?<3A#85@&36';+3<:(+-/&('()2H+@E;'**<*>==),"2)*46&9:4$&C@3B!#')&:$;4372+#;2*F3+'1+5,E=<.$>;B#E4&$=2!:8)4,?AC('%789E%%*B'0(?/*,'>EE2'=-13A%,*9@=9'H!<G24>34'"*@940HA2EH>CC-/-%7EECG='<$C"56,-7(C)*F2"/"B$*8A.9292E1.+=,9F><9?%4F;.4:$??B0+$*:=,5F/@+0"$4=?5641#1*?6/)?'=17C;7:F-2+)?F='B-%!89"&)C)34224
@r7734
GGNCAGAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAANA
+
('$#(&+$+##)!+*'"!$!"!#%"*&(!&+!%*#"%))!"('%%%!!%"'$"#$'%"$#)$**(*"!*)*%*'+%!#%$$"($$##%!!$+')$%'##(&!&(#!!*('&*$+#)(
@r7735
CTNTTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGNCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATC
+
'+$")%&!&*+$&%#!&+#*&$%&$*&&''%+%*($%!%!'"%!"*%%)$!(+&+%("!$'&))'%&+))!"#%'#%%&*!+%("*#!&%&$++)#*&"$!)*(*$"##+*&%(%%*%$))%#$%&))%+%)$"!&#+")+)&+*#&*
@r7736
AAGGCNGTCNTTNAGACANTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCNGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCANAGA
+
)'!%'#')%&("!*(#%)"++(#"%"#&(""%*+*$&*&+('&"&("!(++))#!)"'##%%#*&$*#&%+$&+$'%(+*%!!&#)&%%(#*")(%)(#'(($'"('!%(
@r7737
CCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTTTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGC
+
=.0B@!4'1,CE.&>'8/16/0-%5F>;F/<$,<!$G@<<:B&C)0@,F5)'7E(=<6/AB8.(EB4'->$-.1?7#G@66&D2><09C$0"3+#>F=7BBA9";>*$C8&H4E'"2"A?:2?C/5*@6H#(><>9)/C?-H.:=
@r7738
NTCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGTAGACGATGATGCAGATAACCAGAGCGGAG
+
#6,((?34(<A4%E=5!%-@*2',9$.3$A&=:E-!)--4EH$+1!1>+,C84?/)442&;CA$/A52H=!0D"!<'4G"F",F<#@/B<??1<+%E#2:/1,5#*&>?::F/)@5(D$07F&695<@.7@!9AG,3?3:(?<4(2G-8G8)%<(;2?2E;"$"AE0B0#F=
@r7739
CANGNATGGTTTCCACCGTACTCGTGATGAAAATTTTGCATGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATNAACCTTCATGTAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGC
+
*%#*)()%(+)"($)(#+)'!%$#)!&(!##!+&)"*&%#%&&%"'+&(%%()&"&()#"%'("'$&&)&%$"+$%#'"!"!)'*(%'%$%'&&')()%*)'*++)&&%!$*+!'+!)((*%++$)!++'"$()+!!("*)+#!'#&&$#+'+&(#'%$!'*"(&$"*#'+#
@r7740
GCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCACCGGCAGCACTCTGGTGGCGACTGGCGTACTGACNGATTCATCGTTGGGGTCGGTTATAAAT
+
>&C1$!%#7:EG48$D>H,D%-2/%,H"8'<6=G.+!$E(+36?.+02F,@%/A>?%=F(?:2%$&91G97>&@=@C@+B0C2)HA4/49E+H90&122
@r7741
GCTGGATAACGCCAAAAGATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAA
+
+-?F+9/:74<7G&!?-:61C",G0GBH:1C1;8?(D'E$..-!D?#9:BB*-,<!;5>:/F?;*6H782-DF:/>&A7D+@3D1&,)E729?D/=3E<</8&F=H9H;"><.)!$D@CG9>!+?
@r7742
TCANGATNNNTTNCNGNNNCGCCGNATGCGGTTAAGGTGGTAAT
+
)("()$!&%!'&!$'&#"!%*(%$(&*+&""&+(#())!&+%'*
@r7743
NGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCNGCTTTGTTCATGGCTTTNATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCNCCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACNGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGT
+
$':-+3%5.@.9?F2':,(AF7.A!D&*.%:&DCE3*&:"6A1);,37636:&17"0!8C%1+%=<".4#:8989714?F(&)6)=C>!+'@D#495#0A+!;E*G$0'>0>&(F**.FE!8B&3%G4<F60!*F$3+9>;2*39<H4;)-'./<(G/:2&/H76B2>D>-@D(/H**>'88F'+,7H4,G+B4:4:8*0@5;@=1$)<.76FB@0FC.9=+B!99!-D5-1)#%/>7!2=F/',::G45"=%1'?2F4'0!=#G?A>!5)$E:3<*4A?G-2=/F0-"
@r7744
AATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGG
+
8<=E=;!.,1;3;6+AA8?*#@2(H,AD(3!HB)$A9+*3!+?/,$F:$@+-!'BD>B@$5++!3)A
@r7745
CCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCT
+
B@(9@H2D@,<>>@<7F<<D!>.8/G+#7:0%:/*GC(+:':G<-@A:&C8>-D8,:>D4!E(C'F;)@,*=9-@//%0
@r7746
GTGNCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATATGGATCATTCCCGAG
+
+$&%"*&()****!*%$'&'""#!+%"+&!'#"'$'(++&"#*'')")&&'%'#(++#+!%'))"(+*#$$)(
@r7747
NAGCGATAAGTTTGCTCAACATCTTCTCGGGNATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATNTTATTNTGACTGATAGTGACCNGTTCGTTGCAA
+
'*&+#"%&%&$%!($"%&"$'%'*+'%')"*'$$"'$!(*&&")#!&!($(*)*&')+)#$"$$+*%&!*"('"$'!&*)&%++)"('(*)#(&)#)'&$%(+'$"+('&%!*&#%)"'&("$!$%%)*''%$"#$%%%&("$"
@r7748
GCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCANCATCGACCTTCGTGTGAAAACGGGGACTGAAGCCATCCGGGCACTGGCCACACAGCTCCNGGCGTTTCGTCAGAAACTGAGCGA
+
*1(1%@8CA*)=<8&*(?/?/!:B"'B>BG:-.4$%'/#7*(#>.>7$@(1;?%<6-%7"D!<E7'76!7@D7HD=D2)G@9%1=(C.E1/$D4)DE&%D>+BF3#*+%.*,0/A*0/111'=D/G
@r7749
AATTTCTGGGTAGATCGGGTTTCGCCGGATNNTGGCGGANGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCNGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCNGGCCG
+
6'0*H?+B6!;*BC@7%3+/6)%,;%1<;:4$:&81(B?:@5+"#7G.3!9$3C6-C2',G?<7/&"9=B19G$E&3'#H#&8E((2%A$#=*+D.%&>0)1!BC!'$+*C9+@!<D75=&2-%.#71B$H58=E
@r7750
TGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCNCTGAATACANGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCNTATCGAA
+
.*:/#?5*-G8+-73D96:#$(@%(=)%'E<B-,<C3DA;*"%9"A;E+%FH3*')?F8B!A))=&,H;"4-H;735%(4#;>58FEE44);7D4."?DEB+5+11;C"99<$&=D7G@22CB4=*D+=6=B@5G52$<<B('0-+A=H.:;(>4
@r7751
TTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTCCGTCNTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACNCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATTCC
+
-CB377G@<A1)C9&D"7A01A*A6-(*-'?%:63/<40H(*;-&F.H>,13#7B1<2AA<+>CG'2$&3DB/F>%+CG8,,"EB,.#*'8>8C:G>$%B@%+48*1A6@!B<"G!9,87:2D/H'%&=;5?73/5$.
@r7752
CTCTGCCGCCGTCATAAAATGGTAGGCCGAAAGGGATGCTGAAATTGAGAACGAAAATCTGCGCCGGGNGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGG
+
@G!+F!58!'0G84>+D1@.-G-AH;%H;>7!=<F-41'0**/?+CH552?/%19C;=6C1@8,BG.+3A6G2)<;E7F77'G,"*'"A&>E!<*37+F/E/B<;C1*19%ED%
@r7753
ATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCAACCCCATAAGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAAGGCTCTTTCCGCTCTGCCATCACTTCAGCATCNGGACGTTCGCCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTACGNAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGT
+
$:@6+5";0"85$?:;GA(H;&5-%=.@B66;B-?@6%H'.7F>-DGEFF269-H79+C';2EC)F??#A*9<267<8@>1.A.1'&8;$&.)/?#.<:G?'94H"G)+9E)AC:'$B(,?'G84@,D%)C$6A4B5H,(,/$=8(59,--?F5$'<=.-%!H-G9!"598+&?>3*9>DF<8?,-<G2H97-"B#.)%2:>#=:.#"*<*%:1-=)7B1;(H:H&::('%7//0$H?/A=<(&4/?+9H0'0G@47BB4#B
@r7754
TGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTNATCTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCAT
+
@AF:$H2..F*D//;5GE*"8GE(.0-??>=621A<528"3;2*"#C#C-!,F0E,+C&B5:C"((';;>=?D2?HF)>8D5.)-#+.=1B47-61F$&">8=)2GG.,'*#7H1)23.81?:!C3,6*8(.$8G5(=5'%#@&5G$3@1;C2A';'
@r7755
CCGCGNGNTGATANTCATTTTCGGGTTACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATNTTGTGTTTAACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATNCTAAGTTGGNATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTNTCCAACTCCCTGCCTCTGTCATCACGATACTGT
+
(#$%*!&')"%)""*($''&#($$(***&&+$"&#*&%#+$##&*&'*(*&$!&%'+*$$)"&%#!&&"(+'+("'"#)$'&$))+)("#+%&)'"$$"!!%"+!+$$'"(+&"))$!'$#+($)$&')*!!)#!)'*$"*'((''$$#)(%'*"%$'!"*&%+(&!%*!$*(+*&$*'))*%(!!'"$#)#$"*+&#&"#+!$+#*$)+%&(!$+&+)*+%()!$+)%+%!%('%')#&(%*$#)$!'!+$$(%+&&'!*%&&!"(&+"&'&+((!'%"&%&)#%*!$'!*+*)"*
@r7756
GGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTT
+
%+,CB:,-*>)8#";#'#!B@?B9F@G@#*'-;7:+'?"G5+8&"@>/!&3D8.+;G:*.G5)0(
@r7757
CGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGC
+
'G4'7>'B?*1(=)C-<59,'+A-'2>6+.,3D=@E5$*!2>B!>.
@r7758
GTGAACGATGCGTAATGTGTTTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTC
+
:6&/:C*D=?/)-=E##D">AG/16&GH/2#+(2+H:2>262.=:"3$E@8EG=>,#35:3
@r7759
TAACCTTGTCCCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCACGAACTGACTCTCC
+
4*.-A(3G4#E56!*@>0F6C%.?('H$)9+(E"&'?*G2-!EED$><>E/.6H/'(%($8&':+&:.5)'6-1(7*7@)?0D,DE-F&#H?A%)D1$+6'+%/>8(92+F92DE-2*B3B4G=(:'47?4<6&
@r7760
GGTTTTGGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATA
+
;16:E9!B3BC!6-A8>"47F!',H/;?#01<G%'A1,2:@4>90B<HB?4;)=>@#DH
@r7761
NCGAANTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGGAGNACTG
+
+&(!"!&!*$(%!$(()))!'&((#*)%#'*+"*"#!!#''$""%"%(+$%&&$$"
@r7762
CTGGCGCGACANGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACC
+
&F*AD59<(!$&:%E0&0B"=('@B0=G4>F.+H&.1B@)%#&8G7GD)0+83!
@r7763
GGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGC
+
*7*-9)3<;+;60AA"!0$A%+/185".(BC7FH*$@)<$D15:).=:
@r7764
TCCNTTTNCAGCTCATAGAGATGGNCTTGGGGCGACATTGTCATCATATGCA
+
'#)'$#**+#!'#!$'##&&))*#(#%((("$$$"*%&(+(**)+'()*+%'
@r7765
TTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAAACAACGGACTGCGATAATAAGTGGTGGTNTCCAGAATTTGTNACTTCAAGTAAANACACCTCACGAGT
+
)740)<:*EA$#EH@17)>"5HH)223;2$?)@+$-#@D8AB03:>AG#)93'8@$?#C9(.7-2E?D.F4?##0@3$A",-9$E"55%=:1'.B..6C4.&6F*,&$7+-@7:;467%@:9#F@-E9(=C9$@,4:"F(B<@$/G81G942@)7<+?:1&"'@!19'C/:G!+1@&)?*4.<<9,.3;7(<E3+2+4)#,6EHA4)E4>+6=;#ED-?H>.4B4A.8!678=$?@9$1#H$<@>3-6E+9%--"H&#%5GH:.@>A3
@r7766
GGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGATATGATGAACTTGCTGCTTTTGATGA
+
(6F"D;2./>&'"("0B).C2+?65$@;+H4%-4)>5$FH?3&78&4875G38%0H>0/4;C-:=06:,/$:5&H3@GB%4#C+=!,?E=A,
@r7767
CACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCTACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAG
+
7,4@G+9+%<1=F*FBA1+)GH';4/.A"FG<<#6'<!>)E-'+7";F>B+!AD@D).!/55B98<;>2?##B"-'E*B*)C,F9%D.4<G**7>F22.8,0+(.0@DD24B2$-*A(5"4!<<48H92&=+'H5<3+@'A/$.9G>=B<;,.'4&'$C0
@r7768
CTACGCNCCCTCGTATCACATGGAAGGTTTTACCAATGGC
+
G#<D6.88027$&),*=D(0A=,-1505&$)0##A%H%./
@r7769
ACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATNAATTCCTCCAAACCG
+
.:""-*5&>"F4#'77.GEFE$E/H+%+H2-%A%3>;49CG#A8/H87BH,0AB*
@r7770
NACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCC
+
&9>-C6:B-1*#)60(-/EB&1=H;B7AA<E8='G+.FCE2>D0D7G>6(C'.;4$D,,F2A"0-&!8B24H81?/3/7537$<(*)AF0H"<9$.D5D!)9'(?!BA2#:?GCB(,0<;,)CC/>>D4E#@D0:2++(;8:0:<0?(;"+@0?=->DC;/>8!;,8$0,*%C8-D4D/F2+E.!%FDG*.'">GC4:+<#031'8-7G=:36-(,"#<)
@r7771
TGTACGCGCTAAACCCTGTGTGCATCGTTGTAATTATTCCCGGACACTC
+
8&=(53DE;-D;A+0E:B6D2%0(:>%/%#1E2HCB3C#7*$;%=EB3=
@r7772
NACCAGAACTCAAACAGTACCGTCGGGTCATAAACGGCAAGATGCGGCGNGCCGGTTATCTG
+
#07G%;*&/C"/FD;+@!@#!=%*33!=/-:C/FE?*,7(@#?.E-)*&0A6(5(C8-F6D)
@r7773
CCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTNGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGAAAATCCCGATGTCGGTGCCGCTGAC
+
!E":%&B2<H*+!7>D1BE#9$5!(=/@F2F'.:'88!:@<C#5G1B<0$3+9":#(<)-D%7@2CB$)=?0#@,;(0@2842D-6@H,'(5;8D'/@:.1.F;)F-C/0#,:B2!4$;=.-FG&"(5'E!@<0@;#BA6G3D'7AG30(-064E=;0*H?@:#2&/?8*;
@r7774
GCCCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAGCCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTNCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATNCACGTCTTTACCTGCCCGTCGCTTTNGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTA
+
('$*+")"'')+")%%&$&+(*#&(%(')*(()++*#)#*&'#*+'"%"''%)'!'+#)"%"!%"&$)(#%!"%()+%(("&%%!$++)%*!(!')(("!&$$'*'*$''+#!'&&!)(#&)&)(#(+$+)("!!(%$&"%*))%"**$))*#$""("'*+'!"&)(#""+)&+!+%+&!%$!($!$!)#'(#+**()'%$)'$+(#!!)(%"&+!%!)#%!*((*)$&$*#&**%*+!%&)#*&'&$%*+(&%+'%)%%$*&)+"&#&$$$#+()$(((*#&'"'+%&%(+"$+((!&"'*'$$)*!"&)%*
@r7775
GCGTCACCTTCATGGTNGTCAGNGCGTCNTGCTGATGTGCTCAGTATCACCGCCAGTGGTNTTTATNTCAACACCGCCAGAGATAAGTTATCACCGCAGATGGTTATCT
+
:H<.F66$/;!2$G@8%561,1G.G!A4G+6-E'18)%7AC<!1<;*.A,6"",28*"H"#57'#22H:,@G&?E5:$5'D?70,<A'CD2*)>,C7*'/'!3=@"82?
@r7776
CTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTGATCGTTTCAATCTGGTCTGACCTC
+
E1#97"?<A2!.5B/:2>?287%9'05+BH@'4,="5!H<)&*$*(1B/BA7<9>-'B*(H5GG#%?"G>"#?E>A'B2D;1:H))B0=!?7?#1%1.F.+
@r7777
NGCCGGTGNTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACA
+
"0,&2G#+C'0#6<(86F<<>AE)F"->*<2-@!"'@48*6!E&!"2?)@8%F+(E?A1C(*H@5.=+0&$H9A5B7=GD?7.H&10#<5=2("7E+),5(GH<=C+)8GBB,42,+=;&1#=%$+!(&-1.D,+$,F-7$%=(3D4:EG3?DC#$80E
@r7778
TACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGC
+
0&*A-H,BHC?A2!#"4;D&18;!&,321#B9EG.?A@G=(<F6>@#7+47?-:'5*
@r7779
AAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAAC
+
>68,H*B?33/)H"*A*B8>H:%@38-G;CC?'3;4;/>7#$E%(4(C//$1E
@r7780
ANNANNAATATNNATCNCNTTNTCCCTATTGCANNTTATCCTGAATTTTCGGTGATGCCTATTAANTTAGTTCCATCGTGC
+
##"'!$"%"(("$*''#%)(("$"#(&()#%$#'"+*!!))!'''*&*'&&($&!*&%+&'&%+))'+%%&#'((%$!)(*
@r7781
GCAATCACTTTCGTCTACTCCGTTACAAANCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAANCNACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATNAACGAGGGGCTGTA
+
-:?7%F*$!#;$8/H+<4;CE>/:G>.E3:7>FH!A@:(D@."EE12A'%!>:9H<++4C3525.%+,-GFDE-3*"HG%0@@'-;+65.1.;,(1E"@=(<:B&#3$3(>;%E'52"1H-H6
@r7782
TTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAA
+
.EEA/H5H"5B9F"8%CFB*"371;'3(5=A)=%!-*(.)BG15-H:"'C'->H'76#"!/BD1GG$?"E)9)<;0&A"B96?29+#,'?6+@F%/
@r7783
AANNTNACNANGCANTGGAGAGCGCGTTCAGATAGAGCCACTG
+
*&&!'"("!%%&%&)%''+#%'!*%($)'!&")#$*+#$##*&
@r7784
TTTCTGCAAGCTTGGCTGTATAGTCAACTAACTGTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTNTGCGTCCGCATCCTGAATGCAGCCATAGGTGNGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTC
+
&/@5B65G=:-49495B'6+(=B88&"$9@?/2B(6+(6,$.0C)"+D:3,(C3';,*CB64%7/:H'!/1'0&G>E173?D1<%@!6#$A8&E>/*.H9+FA=,F!?(-+;!,D")491F%.D)207@E)H:,>%2%:2F7B-=A-F.,1-"'+)F9%:A3$76>&2:8=-8+08%?,79@=9%8(".BE7=&A?87B)GB5:?*AH-F,&3<'F(H;0;".%>%-;-$2<C=0%CC-D>.1A1<!<.0%:B5,>##,!D&89(F)G&-+!1/-F&A:5F%8&HC:FD/B"&8,A%9'$!&';.2(0(+<A@&GHB-,$"!-:2322)-&<9.*<&&$AC=.#=!+7+;?#@-90(@8<*-
@r7785
GCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTNGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAA
+
5:"?/!0%?0%17!#<E9:1G5#@"=8$G,6B:"AG:"/%%*+@!2-<,;0=E,(0&"%A>F3==/--F<!'.":60$3>89C?3&6(756DH-,,1&F):A2:FG*=.@!4-/(&!.F.FE&%><@F,=%
@r7786
CAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAACGTGAGCCGNTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGA
+
?0+(".)B)DA+*H340!F0137A8-D".23?%E+-$A:67#(D'#+B4=(8':2>=189=?+3E'B5,=*#E4G1#F6E3<&01!))C*/7:$8@H68-,%D,B(2B="*F@807();9*-:.9/>:('8>'"2?<;<3"28+%2*?*&%C')A:"<?#4#BE?8/HFH@H-=">@8,=.!
@r7787
AGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCNGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGG
+
C7.15GA)5>7,;11%7/1E#)<;9@**E+=14(>*<!'&.+#@"-17>?>##F.!6=$;78;)1,3*%&'/,DE';#&*2@21*C;)C(FGG&48GD#F<:8*&<#:1E(,2D@+FC=)#.2.63*=-.A#
@r7788
CATTTNAGCTGTATTTGTCATAATGACTCCTGTTNATAGATCCAGTAATGACCTCAAAACTCCATCTGGATTTGTTCAGTACGCTCGGTTGCCGNCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGCACAGCAANCAGCATTGAGAACTNTGGAATCCAGTCCCTCTTCCACCTGCTGA
+
!&"&"$#+%)$"!""#!)#!"&*(*#%+()'#)#%+)()!**)&+(#*#+)(#$*$'*$!(+($!#+!*$$&*%*"%*)+#*%!(($#+#''&((&#+$!%+)"&%%%""&'"*$$&*+(!)""&#$+))(("!"$!'''#(($!$(+(!+!%####"+%"$#$"!+$#%'%&&%(&#%$'#%+))$'(!#'()%!&&!#%#*+#"+"'##&+)&%!*)"))#&)'')!
@r7789
CGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAAC
+
2"AE5E,D0@/&604'7;$DH/E;97D4>*:*EB+H<.F;1;&!
@r7790
ATACAAGTTGTTTGATCTNTGCAATGATTCTTATCAGAAACC
+
+5-&>0H1*(100*%-9EC22G&>;DH?D2;21>837F*.96
@r7791
TGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGT
+
A(B@B1C/3=#4#&G=H,;F2.8E01%7B!5%H2(ED3,:!E?H<%4*(#)8+":%-8<<&(1+H(=815H/D*+=C"%==#@=1
@r7792
ACTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTNGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATA
+
!HB+)2+>2;>-4+&@$=0-B#>8,31-*)3*$BF7-B*F?E*=3A78:&74AA&4A<(*:=7+=A7F='C9C!$68+1$5D92)2#H@,C!$HH2>3#>A$6("=)3D7E>,ADF//")2-DGH
@r7793
ACCCGGGAGTGATTTCCGTCTTACGNTAATCCATTGTACTGCCGGACCACCGACTGTGAGCNNCTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTA
+
+2!>)-H/6-1?"39/C6,-BA=;'37A41F1)H>.+(5($8!#'4B;EH"A5%1)!)"%&GAB4=(5&;6"5,3+290.!>G!>$D/#,%D.=)B&8'D0/4>H
@r7794
ACGCCTTACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCCTCTAAAACTGGTAGATAAGCCTAAAAATTTCACTTCGACAGAAGANTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTGAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACNGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGC
+
>&%<12C<?,.!;?,>F=AC>&4&<;$3<F15652%'GDH=5/9@09&)=B2($BC(5+1;*87#.;D4'&A4+)G7-?<"F:0@B6.<%',(-9AD$D.=5A/0:D,>D39,($/F4;:.?3+:'5?)!4(=?>>;:="E-G6+D&4'0#H46<+(6FE,0=3%@224$#?7B3=%'F'29;D:?H(&7*)F#1FE';'H>*0:+6'+;-9+(!!8!(2A@:=-#,-HB'*79$@#*3/=0?9@E7G*BF/D18652H"#>8+3;96EF83%+H@;+43A>$F6!2.5#FG;1):4>(&:94(?CF*&4G;4AD&?4%!"CF-*0*'H9$1=1*1/<+=9B'B9D>D51&@>G1?1@*4'=1,-H1%=92G3&A%+(>4)6?C'!:B:<&?-80A>6-+(&&G97&>0679F!0"$=3*95&H;"!57;C""64H%48&2F*FC2F%B8#=&1
@r7795
TTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTT
+
/@DF+FA;5A'%#(B:9A:BF'D<A84&$)2H#>D=$181$$*4.,5-G)>&E%4D:7>6+ADC81%=%#(A*D8))45H/"D(AA=HA82@<&"F>0038$.&(')=BE>'*
@r7796
TCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCT
+
FG;=6C?*A=/"0-%%$C2@6@'G/*6'0(5;7*C4&=>B')G+/':0C-;2)?4:H'97(D@<&#/+BF2%5&'(FF$F>"%'3(GF2=@<:/@*3!/=7,@*5:'5C,*;5<:
@r7797
GATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGT
+
,908%<9)G.%?;G,=9,H7$@092!A)+%*D.(0H3-/=<!0F>6!*&/)48.)FF"-%E:>'2&;&/75700**E*>="6#F4
@r7798
GCCCACCCAGCAAAATTCGGTTTTCTGGCTGATNGTGCGATAG
+
DF)/4.A6<++'3,7*4+D!>=';AC-G("',-683062&C,(
@r7799
AAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTNAGGAAATACTTACATATGGNTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAAC
+
5$:?+)F%H?!?)=.>#3GBB>3)G8@=93&*D3079"-;(!:-0.23@",9?0:C"C3.;A3;/B262FHG@(8E*=2/C+G*=4E((C3;>3$,H')3+:&>%#'5==97<;8G/A+A5,?4)B='
@r7800
TCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACG
+
.<&"A57*D>'.&*/3F</:9;B4HB$?$HH*3=)@#DH5';A9&('
@r7801
AAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCGTGAAAGGTGGCGGCAGCGTNCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGNTGAAAATCC
+
CH-H1!?A'%/;8($213FE>E3,!B/>"%BF;%$C==@+"-0(32#F9%-<!G./&.(',:$;@F#@.:#)/:#2"(8/%+?2#4:F082*#!194+#=2&C"3?B&5!DF$:%A:8<EH42D>(E141)C554F)3:(,#!,3'44?6.??53-H?#2(>8H8E>&"=DEH&*EB7-4:6"<2,G!@';(#,;>/F((*8A=*$+"F:?5"/"-0:6B6";@!@E/1AF#;!;'98,/:9+36'3'H+G4C@3@)9&?.59)9%*2D"$>*
@r7802
CGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCNGTAGTACTGCAAGAGGNTCCAAAATCCTGCATGTGGAAAGTCCTAC
+
(/3<0(HF?)%93D6F),C/(&,;$C1D)H<66/B!/4<5?)1(#F$#1?@:/;C;6D</198/@5$,*8FD%F'%69+6=@;-<-'H#,=8,#>87:1H&EE::FF+5"6AG?!(:<8H72$,F(5(1$(=:<?$=6,3D6%'>8)(!.&3/A@A+.-&"6;GA?9,));H.2.2AH2)9>-*5
@r7803
GGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATC
+
/CF*"?=4"H$/8G:#5'@=93+"C0>&;H;/C71@BC@,+2#33;?!"02<)7?#">&;0!#<C4=0C+H2;19E3/>&G:;F71.&A=85H3;8837,#9
@r7804
NCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACG
+
"90%5%49;>+A&5:D?(:1;:D.@!91+8'B9E;"6:F$4<",G#(=6CF<.C!GC63-66"".+43"9&C1/!:=080@4!5*+
@r7805
TGGGATNCACACCGACTCATTTTAGCCTGGCAATCGGCATGTTAAACGGCNTCTTTAAGGAACGATGAA
+
DA(?)EA0F8!=@1F6*B<BHF<@H=/-*/>)94"7;'B##$D*5,$4/;#=H=E:+/(&,D#C<*&$+
@r7806
NNCNTATGCNNNGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCNTTTTGTTGNCTTCCATTGTTCATTCCACGGACAAAANCAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGA
+
"#$"'(')"$$""%+!"&&#(&$"'$"&)'+%$)*#)+%&*%%#!)%*"""('$($&+$*$&%%%!%(!)*)")$(#!)#&$++&%$#*(%""*#)#$"&#)(&)*!(!*+$#%"%$*+$"+%%!&($''+&)%))"$*++%$'&%&(%(&#($+%'%$""'))&++$+!"!$&$$($&!++")(+$*
@r7807
NATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCANGGAGCGCAGCAACATCACGCTGTCGCATCTGCATGTCAG
+
!+%6B#(2:13#:#(.D>=>6&:2=3.-./D"%C35-5(@-$&A.1!(G(0(26?*,:+9966(8H;+0@:=H8/D547=.?B0'=>
@r7808
TATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATNCCACAGCGT
+
@,4-5$$!$EA62=G7>,-%"FB8)%D$;&)C!5H.BB?,E2'3@8/)-5"3@$(.#(7D*7@")'957.>%(030#="%75/B%93:FABA(
@r7809
AGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTC
+
=/%$'+;%60@'B:!80=<<G64F&#">&&54&?#:;;+8+7399'*C,05#>A#=@@)+G037*0CB=+#-1&D7H@E-B14G)=43>B&-,BF-"1?1)A>G&0=H,H$/!GF;:0B2*C#%7;-)2<'
@r7810
TGCCAGTCGTAATNAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAA
+
*%'.<3BC:%+:18"8/:679@9C6<E=>1"?)1!!<(&4E??%$E$?2'::*$2+,'E975-.
@r7811
AAAACTGNTCTNACCCNCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATA
+
')$#'*)$*&%(((&%!+"')'&'+*)%+&%$%%&(!)+++'!$!)++()*+("!%)&
@r7812
TTCGGAGAGAAGTCTTTCAGGCCAGGCTGCTTGCGGTAGGCATCCNACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTCTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACATTGACGTCATAACCATGATTTCTGGTTTTCTGACG
+
$A0307#)':!!4ADD(=.6>2C(<<-A6.46;8'=&'$00')89<)!+6B,6!!358HB7/2,BA:9E=8C#*-(-."G:(99"93H-.0.<1>1":H+?"B<:(*6FF3-83=GE!(%7)+)@)<?6?0+9<E3:8<2,;F0<'%/<5%A3&)A!<B%!)!%&706(2.7+&BD(3<@27.6*3@*H&H!.-
@r7813
AAACGCCGCTGCACCGACAGGGGGAGCGCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACNAAAGNACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTG
+
64+&(H'H/)H<E#46.#<@;:3,*E>B0!6CE4+.<D0@:#&&H,0.HF;2:!?!9C$"5>2G6G:@-F;#-A*8FH:)11AG+6(&.3"3G910.D%"#%<=#<:?;(7D3"
@r7814
CGGCTGNTTTCTGCCGCAACCGCTGCGGTGATCTACGCGTTCACGTCCGGCTGCGCCGCGCTGGC
+
B71200=E.3GG%7;C)"8@9<2.1+0!?;%#,-)+&7#@.'>;@,@<5/%5)#)7?D",.83!;
@r7815
GNACNGNTTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGCCAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGANTAGTAGATGTCGTTGGCG
+
!!('!&'*)+#"$!**%"%$'&"!"%#''"+#&+'$%#)(")(*''!#$#&!&"##$&++*(+*"#'%!!)+&!(#*"&!"!($''')&#&)"&!!)+"%'##$!)'%#$'((*%$*"#(!((*!"%+""%$(
@r7816
CTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTNCTGCCACCGGAGAAACTAACGACATTTATCATGCA
+
3,0D6<=1BG/D>H=:6@35H>067H/$=/4D@5.%6(>899;#0:0$$@+**1!H!363-3:)($0./6H84==;$BEG/H1
@r7817
TGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTAACGGTGTTTTCCGCGTTACCCGCAGCGTTAACG
+
:%!#(2:>H054H-,?#+AF$6*08G%'&43"3:<5%>-:(12E7+A#'GH$4<<2,-5$%*<D/.'H%@H!."@:-3
@r7818
TGTGGCAGATCTCGATGATGGTTACGCCAGACAATCAAATATGCTGCT
+
'80)!073H/A43@C%.:>@"/!F*:E",D/6CH1!6*%<($:&2"25
@r7819
AACTCNCCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAANGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTNTATCCGCAGACACCGCACGAAAGCTCTTG
+
%)+"#+&(&+&$+&*)&'")(+(!$!**'$'$#+('%*$&**(##+'"+!"+*!$"**&(*)*&+$)'%!'($$*#*%%('(!$&+*'%)(")"&*)&!##$#&!"'&!(!+'$&'%#%#%!"'""*%*
@r7820
ATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCT
+
CE;.F#<1<%!H&;:#D<-6!6(>07.1%F1455,1B=G)7)C<.62#>7/*380:8+22*:!,-.F3AH=?$93E=,'$>$314D,*.4EF4"/30F0:),)3";AF(
@r7821
CNACNANCTNCANATNACNCCNANCANNNTTNNGNNTCCNNNGTNNTNTGTNNNTGNNNACNTTNGNNCNGGNTGNNNACTNTTNCNGNNTNNCANCNNNGNNANANTGGGTNTACNNTCNCNNGNNGNANAGNCNNCCNNTCNNNNGTNTTGCNACGTAANCNTNACNNANN
+
!##""##"$!"###!""#!!""$!###!###$!#$#$"$#"$##!!!""##!##"!#!!$$$"""$!!"$#$!!#$$$$$$"#$""!"$##!!$!!""!!$!"!$"##$!##$$#$!"#"##"$!!#"#!$$#""!!#"$$#$!$$#""$!#"!#"$!"""!$##!"#"$"!#
@r7822
GNGTNNGNCNGCGAANACGGGCCGCCGCATTCTGGCCGCAGCACCACAGAGGGCACAGGCGCGCAGTGAC
+
(%$(&&'&'!*"%%(+)("#&+)'&#"*)'$#($(('!'%)*#))#+)%#'!''$++*"+$#%&!#+)$$
@r7823
ATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAANCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCCCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGNCCGGGCCGTGCTGACCAGCCGCT
+
7)(609A9+.3,D282<69>+-BD4EH!4'6A1>2&2<:?"(,=B,7%0$>-H$=39<4"9D&A%A='(*$'*(H;GF%@EH)"+*.71%A9G(&+F%=4/:(#/="7(D'8&B1EC@%B&!?$#(&337E3)658+=+/0&9.1'$+8)1?D0$-4>3?=94>21:/7B:;*)>3%&.#*$BA9&%=06H#*"=F.!%9*)F8##/CC
@r7824
GTGNTTGNAAACGCACCGCCATTATANCTGCCGCGAAGGTACGCCATTGCAA
+
#)$!&'&#%)*+&($%+"+"&$)$))#'*+&''##"*((!*&#*!$'(()($
@r7825
NATNNNGCTNTGNNNNAGNNNCNACGNNNNCNTNNNNNGNANNTGGGAANNGNNTCNNNTTNNCCNNACANNGAGNCANNNCTTACGNGCGNAANNNAAN
+
"###"$"""!#$!!"$$"!!#"!"#"#""#$!##$!#!#!$"!##"!"""##!###$#!$"#"$$"!!##"$"!#"#$"!!""###"""!#"!#"#!$!#
@r7826
ATCNCGTGTTCNANCNACGGCGANTAGCAANNTGTTAATCTGCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACG
+
(&(#*"%''*!&&$*$%"''&'!&"(*%'&$#''(+$$()#"#%")'#!(!&'!"!)#'$%**)&('&#&$+*+%!$)$'()%$"$'&$!)**&")!$%)'()"&(#++&("$%)$!'**%*!#'"'%++*$!$*'"")"#+"(#"*)%'**!!'%('&))'!&%)()')!+#&*+*'*$)!$*'+%*)%"#+#)"&&
@r7827
AAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCAC
+
(F=H@8#2B+0/B'.,<B20/:+(!5?('%/'/3-+5'!439:@*8A/4",7%$077HB*=='"')CC=39,3@4$&C<
@r7828
CGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAA
+
73A?@>A/5D7-2(=32+1B2,2F#F1"!@%$HC*4:>BF<;(*H*.:'!8A4H
@r7829
GTTTTTACATCGTCTTCGNGCTGGTTTNGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCT
+
E?D;/H.@#'@*:'@4B*@B24#3%*:=7%3HACG$"-F>=&;"G#+&E99-H($/><C;E7?24>'.0219>%-=!HD94?/!&A!C7#@@?%#*D(:F.'@H(9@@E#&*02=!))11E,"+-3
@r7830
NGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAAAATCTGGGAACA
+
"#*))+(!(!))"&"%"+(+"+%+#(+*$'!)*()#&#$!(""$!#%)$#%&+!##%'"'
@r7831
CATCGGGAAAAAGCTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTNAATCGCTTATATCTGGCGCTGGCAATAG
+
8"+2F$5G'6&;>068*E+A,4ECD7''4)'4&:(27DA!BC5-7"F(7)2)8C0HGDF+%&-%E>B1%A@F8H-&;"%%#7-87&/"27*C4/50&(/;F%*95#?D;,'<>1+0455<->H-:*-/-F10)53-709H2GB1DB.@110G%;8*$4"(E=)EF%#!?5,'0#:5.=-99>@?BH%'9-'*23%'!7<>@0(:75.F)6+?!#C./0<%
@r7832
CAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGNTTAGACCAA
+
B0309"B%&F"B>+0+#B;>A+8,!BCD80>HDE;+:0$?+*@%E&G*F1F=!5.<G$7,'A4?2,7:2):!/=&?4
@r7833
CGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCA
+
+79?019=(;-+"?5/+22D$A8!%)268/8))620B">.=,1A9"/F!B*9"6*1'B
@r7834
AAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCNGCCATTCTCGCGGCAAAGGAACAAGNCATCGGGGCA
+
/8&6,E!/0!#699>83/D,)8B%'B"&.=7=.%.;6'33EC%0%-%AC:"/"<H.>$>9<.3G"48/&#=C8G
@r7835
ATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCT
+
=)H2&-&+%>)D:;.EA?:,-@F<7H"')&H%-B#/D3FH0G0=&"=9'
@r7836
TCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGA
+
<=':B/G<G3A>$8=<H1*,79E;E;729..=&6*EB,B+0H>#:H3+>"&=7(6A"G8#1H/C$%(
@r7837
CCGGCGCTGGCTGCAAAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTC
+
@(B/H#+/(?G6?.=/'??9(/2+F1)*=+(>)*1+(+3$2=(D9):A',(06">8<"#8)*'@(/97%#='")2H4*2='B:<D#A)'9>'"=@F504*&,$-+A$3=,!8-"8
@r7838
TGNGTNGNANNCNANNNNGCNCNTNNNANNNGNANTTNNNNNACTNNNANGATTNNCGANCTGNNCAANNGAAAANANCNNNCNCNNNNNNGNTANTCNTGNNNNCGNTNNCNCNNNNNTTNNCCNTGANNNNACCNGCGCTNNNNACNNNGNN
+
#$"#"!""#!""$""!!$!$##!!"!"""$"$""!$$#$"#"#!""!"!$"$$!!"###!$"#"!$"$"!#"!!#!"!$"""#!$!$!#$"#$$#!$"!$""""$""!!$!$#!$!$""$##$#!$$!#!!!"#"###$$#"!!!!#$!#"$"#
@r7839
NANGNNGCCTTGTCCTCGTCTATGTATCCATTGAGCATTGCCGC
+
!)$*'%$(&')&$&+$$#%%"#&&"'#%%&%!##$$$+)##*+&
@r7840
CNNTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCANCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTT
+
)$)*%!+$!$)&!'%"'"$'"!)'!&$##**)$)'(%*+)')!!)&"(+")(%%)"%!)!"!(&"')#)+)('&&#)&"$$&('')#&"(#*%&!'#)"
@r7841
CCTGAAAGACGGCACAGNAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCANNCGTAACAGCACCACGGTGGTGGTGAA
+
.6;?2!05*+):1>)28B="&CA35C;/:5$?),6,<H:!65?A/31%,&38H.>)FF4<F<9,43'0./=!D&)*?%F8=F?A
@r7842
TCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCT
+
*4"0)9)D!".)$+&GC<-5-1;E,7<6?A1D?<(?>HBB92F9GG))&!A
@r7843
GGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAA
+
48+;(,C@&%3F"5/%9;&CB&>%.(38('&AC7:>B1,-)$=E9%G.@:@'=":'73@>BG%9@(%,86",=>=<C4-56!D-#<($-#4C2!;1G:/<"=?=(GG?H?+E*/!F'07H8B#;/0<<(
@r7844
CCGGCAGCAGTAGCACCAAAGGGAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGG
+
E3=;%'$/C(=#>84D8#?##2$<;&@%+#E:A)!8HCC=./;</-.0&0G'%9E8&364+$!)8+::50/.29FG3D#0-//18HF;$+#>0E2B,8
@r7845
AATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATCANGGGAAAGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGNCAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATNGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACNAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAANATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACCGTTTTCGGGCCGACCACATCCGATCTGACAGATNTTTTAATCGCGAAAGGAATG
+
D7,)(9B1B$CGF;G5:D&!E4AH'$:'/>*@8H&4'AF/%$05FA8@GAH71=FE34#.%,(7/'*C0F1GB')D-#+;/*+<5-%9+5&FF;+)9"#?!"(/'8B,:'+5;E75!@-(D4*;H604!B87.A6!>/(A64&3%B(+:3EH"(#G=>/.69,8G&D!:HBB2F#,$<A>$/5%%&&!)1$*G#7.1+!-/$9(!ADH&<?"='7)-*<A(618:"D:0D#E$3+D1<%3$6+7$1'*@D)$)54/H84E7#*@B$=;C*:"8@:20168.+6)*#D'+-E1>H)8F-'H)!.+:.+!29:E.1%BD*E.E4B=C4%8/+B#%*-0605H;B38$+,C@@E/1;DH%4/H0*<'5,.!F
@r7846
TCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTC
+
CD91/&1B*(,(B+'&2!0A"8*4EE)E;1<H93+2+9$6'A1'B')#6F;.154>#089=!&98,?=+F'>193.;1@H;00C3(=?DB9,)4BE#"F00=;#0$("/8.8?/"$G/?2H7--359@&.$,G8;/(5G<7!.,+H.$4,>C,,*.H:8H8"#.G
@r7847
CCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCANGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTC
+
='**&<13'.:HD?=!-@(&,>47DF!'3B0:;B:+(5++G/H":BD@-&@69$$=(+!H3H69=)2?$,1)@D)>,*"?%1A>29A*=-62@G"23H*H$!D6-:5)5:&3.))"E2308-)8'C@60=F;%@#.2&;.7
@r7848
TCTATTNCATACGTTTTCCATCTAAAAATTAGTAGTATTGTACTTAACGGGGCATCGTATTGTAGTTTTCAATATTTAGCTTTCTGCTTCCTTTTGNATAACCCACGGTTATTCATGTTGCATGGTGCACTGTTTATACCAACCATATAGTCTATTAATGCATATATAGTATCGCCGAACGATT
+
%5@C&#8F-2<?<2H@>>><B2A&0:$G+-1&/+"8@>=-)B"03;;,4")-%9/D6/,9*$6<C):!!;3=;;"/F8D?3#7<16?-19'0,00)C7#0&01=H1$+55)):=#E%A/>8=('-:<)3%4&A"/<7..DBH:DB4AH,,!@(9:!*8""($*-&!1<DHH02%1D:!/-3=D(
@r7849
AGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAANAAATAAGGCATTCCTACGAGCA
+
+$<&.6<C,8:4*&#%@(!867.E1$/E%C='E1$?A2,,7';A,DF02H@*#02+"!G)AE=$7'("4G.E>,2.AFD&+*2;D*
@r7850
AAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCACTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGT
+
=EA"FC1C$/&4:D.**0/<2?7+C&D=:".$7C;/.4</,*?1-(9$/.*;+-$F"H:3+'!+F3$CB=A<>6!F6(+9.12!)!3,##-?%*B'C$
@r7851
TTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCAGAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTCATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGT
+
+-84!;3H:/>5C%B+73+!.*'!E@3E5%B@*2/5?G@&,679*)E>H'C77?#?C$?*("'!%FB>6,6;F;;D2F6%/.E9?03&3*@/;?:>6%)53+*"<&:!"<#E99=9,&$$*11=AD'.$/,.#&)5,7,->=/+"<B#?(1);<(.+?;H-!8;-6/E+5E""'F796,/8'<A3B@!1=G<)&5E+$5")
@r7852
AAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATA
+
AA<9(AD,H668@H"@<)@(7D310H0:>9)F.<?(4<2%A0%=/$4+5!C6&8$-@=)#-?,6"G?.=?=,-<
@r7853
CATCCGCTTNCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACAT
+
7!1HB176;41053.44D!&><#@.B;*8C;D8!>(!!F018.A2E.4BD(@+<;#1(C#2.%-DB>A,#C;G+C,?;9"-5=%.)1D#&:.*9=)=;'#=0&*29>43#H,HG6CA'/#C1'"B)%F.1$
@r7854
TNCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGC
+
$*;5C6)!F=61#29*9#80&%/F%E.6#/''8AG%,)6*GG:H8,/A3/*'9
@r7855
NAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTANAAGA
+
$FB1&D=;?C&-,+D=E%>/44*0?H22>:C21?C)+*FF,@--:=2&<C*!#H1-87G<F5?$##)3C(,*FB,?$"/4CA9,/'?+-@0=&$;D>@A
@r7856
ATCTGGCCANCGTCGTGTATTCCGGACAGTACGTGNAAAACGGCGTC
+
)''&#%*'+&$(!!!**'#&$"&"!$&'+'+*%)!%$(*)$!(!$+!
@r7857
NACGNTNATGGCAGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGANGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCNNAGGCATGTAATAATTCGTAATCTTTTAGCGNAT
+
&#**)*#$#*)'%&)+$)*!+*)))#(&#&&'&'+&%)+)$%+*'*'"'"%*"%!#%$)!'!*&"!()##%+%(+((+%!)!)!!)"%&&)*(%#"##(!'"+$+$$$''%+%'++'&&#'(+(+''+')%'&$!*&"'%*+%%'*!")&*!*#$)%*!+%)$!%'))*
@r7858
GGTGNAGNTCAGCAGTGCAACCATCAGCACGTCTGATACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCAC
+
!((((&'&+*&'+'%)$'#$#*&)!##%**'#&&*$%%+"&$%$)$)+*!)+'#&()&)##""##*+*#%*!%)%)#!$''"&!(**#####)*$$*$%#
@r7859
AAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCTTTGTTGTGANTGTGGCGATCCCATAGATGAACGAAGACGCCNGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAG
+
++"#!)'%$')!!"*$'$"&!!'++!#*'&+"&&('$'#(*)'!#&+"#%(*("$'""!'(!!%("!)'(*""%"&(+"&#(#"$"'*(((!#!&!!!+%(+*"'$#""!'")''%"!%'**&#%!)*("$#!#*+($+)%+(+*(*%#&(%'+%'#)!#'"!'"+$)()##+%)+'))((*#$(&
@r7860
AGCGCGACAGCCGTGAAGCTATATCTTCTGCACGTTTTGCCGAATGTTTTGCACGTATTGCCGCCGC
+
*:'D=4D.1>);(A4;HC7E>>/---;<+'1-5?4F&.3:0/$'<$!)40>>F0==H9:)H9#6-=$
@r7861
TGCTCACCAGTTCGATGATTAACGGAAGNTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGAGAAGCAGGTCTTTTTTGTTGTCNAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCAT
+
F4/4:"D24,4;CC=A%1'6>A=4/0#*F!&3":B"*10/,&2><0%+2D$4DB$#"%.9#>$A=987+<59C7/1*>&AG&8+=E?9C-.26<@1/')"A+G&!-A"F01>E#<4.??$)&7-*:>%8#1&!A5=/G2H(/#.4+$'3BF>06:9&!2.7A@+1CD-52?=1("5H"8$6&;<6<%5E'$H).!C#??/B#5C,$18*</"<F>(D23+(F.BC<&'245;*%!9387E8H26A73'?70A8+-B?A6?E1B(<%<)7735$E#@8,=:EC#F#G!=&ED&$7,?.7)*3>G2./1=.(,06EC3&:EAC,6
@r7862
CGTNCCGAGACANCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCT
+
!$&!$''))+!#')!&'#!&%!)*'+''*)%)($'$#$%$#*'#'%'&"(')$'+)"
@r7863
CGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGNGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCC
+
>!H<*:@H89.9"7@DG45G<<!-;A;='D?11)/$#8F:$062,/,:5E3!+BDF)F<A,:0<#)"5BG")G0!D#)17B'A/*B%>B=$#96E?$&6E-&:G7'=2?5/EE>;1=16?=/:$2#)8'AH'9?BGDE)B4$7A?42D?@&:5'4G!#D5%H7"4*A2"0#;,8+<'7$%:?F"0+>6=9C!2A;'/<H+BA:!:F$-@&";G2-<5&:F<?9?()>H>)HC2
@r7864
GTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGC
+
ADBH@AEF<H"/-(=>C:34=F$,9D*6-;;-H3B1@"*A<G$.F.,@=B,!H.2/$35%42/E'%1=G$H-:*AC'9:;+35@#5/H1+G#'"4#>"!<F33
@r7865
AAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTG
+
3,?+?C.8CG-2/%3+/=)=?A.8*&4"D%'7F"7"H$1'E3)C#>7(D9C</H/1/C'$39>1$!/;(*B&-&1%/#8."3+
@r7866
AAGNCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAANCC
+
%)#$+&+++"#"%%#*")'$&&#(!&+)+(#*+$*!'(&$()&)))*)"'&%)*(+&%)+&!('%')%'%#")%"(%!($)*!#%
@r7867
TTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATT
+
H=?23E"G9:4/=3<F&.#H+E70,"=89G&:H8CE,?;:@F%H.2'%565A>5H,@38&)"1GE!.;>C+*'>F%DBBF3#$?7(5!-G
@r7868
ACAACGAGCGAATTAACCCACCGTTGAGTCAAATTTACCCAATT
+
&%+*'$'!!%&!$%()"'#))"('&)!!&(#)$+#+%$+*"#"!
@r7869
ATTNTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAAAATTCACATCGTGT
+
15;-H8:$HD*"D9HD&;*7/520(>,D986!9G!3?<+AG>9&@&-5$'D&'H#)$0A'A=G=EF"H;2'3
@r7870
ANCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTNGTC
+
.143!46$(H=9+#9:E#<7!/*.-/<5739&*3AH++3;.<?"(&.6C,?3-B=-<<#89.=,C,C*#=,0/?C&D!;(/960@AA=)'/:1:7&8-D
@r7871
GCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCT
+
3@7=-:+83D@HG%'=8.74/F<2-?GG74E#,FABC3++9D%*%=A<:6/E1=00H!;)A=
@r7872
TGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTAAGACACGGAAGTGGCCGTAAANTCCAN
+
?>;"69!F'%4.GEB>#5G3)0/)E>1,631/&7+*#FH"(*8(@?.F5,G>:F.*":?&-'*B0GB)D%DD,!-'"
@r7873
ACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAAGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGG
+
:AD2E9/+/4C353(F'4842.F+<8)(-$7#0H5)#16$'!<%'&1A1*=E(1C@5.D$)23<:?<*#2D0-7;G<0!GE&>G&D9(1@!E9@<7"F#G'',;-894?!="/FH*8>4(97A)?8C@7E!<8$877-&;1)B#G
@r7874
AGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCGGAGAAAAA
+
9;H)D;)8?<-D?-!<?=!%AE':;#(19H(:A=!)95<%<6F+6<1-6E<CE>36,&$+E0
@r7875
ATATCAGCATCTAGCATGCAACCTATCAAAATNGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCANTGATACATATTT
+
C03DA&>!+$-")D!(#..3?$.&:2$C13!@4C/"34%;49F70F"B8&$A8,""@@149,/:/+?#B-8<$C$'%F<D)0)&7$$4!0'-+&",.G>6,598)/B).&0*?5/-
@r7876
GCTCTNACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAA
+
))70?B$)F<!'B844?047"!10#?5!1.%F3C*??0+-G4-DD*98746%5?+
@r7877
ACATGAGGAATACCGATTCTCTCNTTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACCATGGTTC
+
'5H!."(HCD665-H&A()=F'8#DHCG"1>#BGEB%6>&G+:B4$!A;1!0+./91':5&'+66$638@.&*A7#66@;*?"((1B5%?F.2%'@F>
@r7878
CCTGCNNTCNTACNNNNTNGNCNGNANNNTNANNCNCGANTNCCAACGACNANNNGNNATCNACNCTNANNCNCNNNNNCNGCGAGCNTNNGNNNTAATNNTNNNCNNNNTAACNTACAGGAGNGACTG
+
"#!#$!"$$$"#"!"!!$!!!!!#!#!#!#"#!!#!!!!#"$"##"##"!$"##"$"$""#!$!!!#"""!$!"!#$#!#!$##!#""#!"$$!"$"!#"$""!!##!!#!!"$##!#"#"#!"$#"$#
@r7879
NNCANNGTTCTTNATTGTNCGTGNTGNACTNTCGANACCAGNGATA
+
#)#&!"%('!%(!)*"%%#*&$'%%*%*$"($"!#"**(*##+%$&
@r7880
GCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAA
+
B/A8&)/,C98+:3';$1D6#+)2CF603H/"+!,>G8?>)2E7%9%H-AE
@r7881
GTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGNAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATC
+
="5EA2B')2,H.$5&G4+5H$54"=8=:",745(H/6%@CG2A6.62B>008"F5&BB/4,3<E>&G"E)!68(<B2%8)9$E4C#?HC*8>6&*5';33574&59=DH0**3<3A9<,(374/#55'$&,7*H:-C+.+&6;/AF?5,'H0:2@EFG0@EA3,+9=75A:8.4F)ABB:8:(C:;#3/)8$=)7B+63!+@/B.!8/(()*H<9EA#FG-&%%G33F)D
@r7882
ATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGC
+
.0&@'66+45E<4B039?H)@GC8E%.0B%'>'#$;@<"33($2#:
@r7883
CCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTG
+
B2$EH;F?%$@+E'?0).H+/)G1*;8)-5%=!5!<A9;"7:<9%5&9D4<'H:F("3&<CD2=>4BD
@r7884
TCGGGATTTTTTATATCTGCACAACAGNTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGG
+
@76:<9-4A*D-#097&9698EG>;24F2/./C(;4D7G;:?/F"F%H60/FAA(/CHH+F4
@r7885
CAATGCTTTCACCTAAGGAAAATAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAAC
+
H$$0;1,28*/E/#094@4"+:+1&2?(#'(565">&)<#<9%5D;0(5#:.&$&)0<@E:G3+*?EE(AE-%#F!0?D/%+;4GDEA-55<G&@/.29>EF7"6..'+
@r7886
TGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGC
+
4D0>8))BD,=+0B(F+?F)@8.!*(7';)>9!&"8!<0F,.3$3*/-9&A.%D?>34"9%A'</G012*"F.%3:*F(<H8"*?1>$
@r7887
TGCCTNGTACTTTGCNAACTATGACCCGCGTATGAAGCGNGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGANAAGTACATGGC
+
?=859;F!H:,@477&11+=*@#F2&GE$"1274*1/%@H5C60395;92G#!=3/<5*.="D<B#-9C1F(C)!/!G=:<?-CC&F
@r7888
AGNCAACATCCACCGNGNNNGNNNGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTT
+
%&%)(("'"*&$*%$"$!$##!%'%+)##%"$+&*"*%"$%%)**$&)"+%#++*(&$)!#%()')'(!%)#"(*!'!""
@r7889
NNANNAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACA
+
&$'#)+#&#("'&**%+$*#$"*#$*$#'+$(+)$!+&&&*$)#$%%)$+*''&%$+%(("!&+$***)''(%'&%'*()"!""!$!+!"!$+!%&"('#$#%#!($$%')$&$#%*$%*$
@r7890
TGTAATGGAAGATGAGAAATATGTCGATAAATGGGCAATACGAACGA
+
=-"7AB'-)B-7)%/,4C7'7H(293@84@')2931B28>"#F*$/.
@r7891
TGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGA
+
FC=D.*+(%7#%&7;,9(?;%729D@*0''B<32;0."2!#>',@$88
@r7892
CACTACCGCAGGAAAANGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCGGCGAAAACTGCAAATACCTTCCAACGAAACGCACCNGAAATAAAC
+
+&'*7GE,!;>,6"*@$,,%7@E-GA;<#EH$("067&=8,7#<6G+B<25$):)!!G7"-)2.F$-;3C?)>(@0<;!:6(H.#0"F?)'-63G/>87E<F%);4H
@r7893
GAACAGTCACTGCTGCGGTATATCNCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGA
+
%*#+$&'$%#$%*$#+"'$)%#'###**!+$&'!#!#%%'&&#%+()*&+()")#+)%!'+*&))%%'!($#$!%%)**#$"&#"*'"'!"#(""'!&#!")!$)+#(*!%%*+*%)&)&+#'"!$$%!$''&+!((#
@r7894
GCTCNCNACGGATNCTACACGAACCTGATGAACAAACTGGATACGATTGGATT
+
&*%&$#+$%#!*(&'*#&(%$#**'""))"%"+*))##!*($*!")(%'#(""
@r7895
CCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCGGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCGCCTGATGCCGGGTGA
+
11D<+//GH"38A#?BH"#6#21;41:A%E-=&/@'6FE>4@(%F83G'-BB8?//$+./8F.3<*7/(,7=%/@D;@6%6F.E%7"1
@r7896
GNNGCCGNACCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTG
+
&")"(%)!%'&'*+#"'''"*$!$!**"(%)#'"$+"!++%(*$&%#*')###&#*("!&%$%+(#**+)+%"*""!&"'#!''#&&(&!&$%'"%#%%)*%"*"$%'+((!)$("(#(!&+)&+%!(#'$+)'(!*!&('$!)*%!")''&$+)+(%#+
@r7897
AATCCGGTCAGCGTGGAGGTTCAGTCCGTCNCCGACGGCGTGAANGTAAAAGTGAGCCNTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTAT
+
E!<.+B#4;6C>@!2?.'+'CB0!1;CED#=6%&%/<)F0/'?(&"!76H)"4(?9'*F>8+3H1-%BA;;';=!9/-7G8#',0E.<<E:?3CC-"26B+B)B55B81=>:A3)$5#E#B;33,&!9.5+"$9>@%CG*7,;
@r7898
ACCAGCAGGATGCGTGTAGGCGAATTTGCGGANCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTG
+
('=*E(BG,38*/D:5.F0C!C):72<6--5=5#=*@(//9-,F7.1A@AAA&:<2B6'?;.($$*$&'$E@>7;+D!<7(98AF'H@?HB.H;/(*FA9$G-7+
@r7899
CTGNCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCG
+
&H@74$G.FEB12/<*?$&5&*+;16#505&$84./1-'#D8:?%62@8-468G=65*CC'"=334?#."&5:A/4;3D9"8HG:@<A4+DH4/G;7E4A=.-3E$98>?:G8=)5@C>?-BF%-24%*6!=3'.@%@E#BDG>%0G53F4('50%$F+<"&=B;-#G'G=?A:/-!)&*/HC+C?=94<D9H=3?G<>H1AF#2<@+9,GD##107EA&1<$7:4B)4#)?.;?.2':'+9BF$+-,12A4<(!FFD6-*)*7'&!542..BD>'-#5$22A(G1A/B+$7/;"&0/G49AG3D+%(4804;*"())=4@;C=9;AF(%006../%)033/6$%5D;=1?F<,24=>4E=F*@9=G
@r7900
TTTTNCCTNGNGNGNGAAGCGGCATGGAAAGAGTTTGCCGAGNATGACT
+
%'#*"#'!#&#'"##+$&++$&'%%)&"%"(#$%$(*&%+*""&$+$##
@r7901
CGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTTACTTCCGTACCCAGCACCGTCTCNGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTACTCCTCTCAGTGTCCAG
+
)9*B%49>#E&FB>2/<H/.D;CF=5(-'%C1@--5B)7"?3F>F(B!;F@#>/+;E+F01,10157='"*#1,&27C9?>>#*B;0@(#C9/78D@'6#15=*6+E.=&:?61?82?$,?BFB.%/G9&F8DB>7%D*;G7($<A%8.G=DDFD43&$"G!;F"%-"?)"*2)&>&2&<0#*B3>(=A)*C*<AE,$!85/../#$C<BDB3)=8:.2CH,.CF+@!(9,E@59C28700F)23(=39D#:?;*2+3($7*1EA:4886#<!H4;E;A*5!94AC.('4%*7D3=,=&ED@&#4)F)8H*>2?#C)5/151$<H3"=<;-985,!,+A,9,7*3="<?GF:=H-H5;;A3<&&,)%*
@r7902
NAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGANCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGGTAGTGAATTTAGTCTGGATAGCCTTAAGTGTTTGATCCATTCTTTGG
+
%/'#A15-AG1-A=.>=**.&:>@.D0*F+%H*6D79)98E4D<5?":7<C,B<66?;#C''+(",0#<7&799*:$4@E.$G@D;,F,92@2BC?;H;@FF+(+?"FB;-((8B?B(#)11C&2,D!FAG)3@&4701G,96:&@$*@"+9)3(H)@'@A/*.%/>+#,@>#"5"3&5$8##,(:?0'+'G@:A8;*>=//#+==5!??2C06CB:C;4E"5E9.)":9@9H9F1
@r7903
CCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGNACAGCGGCTGGCTGAGGAGATAAATAATNAACGAGGGGCTGT
+
'20($><:'85)/>E58GG:+(AD!F41E:4$%.7!C$C,$GFC.2->D%87!=16A:%:76*'/))23:>H@B66=#/.9+0CA;8';C;?),%"C!*H(93#B6"4A
@r7904
CTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATNCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATAT
+
G%0%627#A4><6)%1'#>>%BF/B)E#50C)G>7%/(;%>#E6+1:F65!E/,"$$H%)4@/*-6'#1:>86<G7?@+)9/24><
@r7905
GATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACNACAGACTCTGGCATN
+
*+"'&%%)#(((&%)+$+%)*'#%&!&')(!$')!%'+$++))&'$('(%'!''!)$&+*
@r7906
NCACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTT
+
!FG2A#89!62?#H>35."F*<'0'"6;B<2'/H0/":">5?@1")#A
@r7907
CCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTNACAGGAATCCGTCGGAAGTCCNCCTGCTGGTT
+
@?#'<C*A:$./*5F)'<3,-62":9*(5F:;4&1A7$A("6#*-E95/*=&&1>/#$=4B#F@6:>D?$G$(5HH0/:F,@,#@=A-#,@0!10&G<=),(2A:,*/E?G5)8:C?E9'9=9E:;9F?4%.#FG2*8FB',>E5/DC;5/C@(DB.!:FH@+9H;):9B<292F,.%<B5<9H/<8/@4H%42'7D=43F.6C%+=+($E,'A
@r7908
TNAGCNACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGNTGCAACAGGGGGGGNA
+
)!)!#"++#)$(+&*(+&)"*"+*%*'!""'&("$)$(*$)+'!+&""!!%("')*)+$&!(+!$!)'!%
@r7909
NTGGCCNACCNGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAANTAC
+
"#&!()&!)*$$+)"&"+"&()+&!"#'(&)%&))$$$&'''*$!&&"$+)
@r7910
TCAGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTNCATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTATCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTAATGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCNAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTNATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTC
+
(5<H+=($F*=6'0(C)-C=F$+6,/'1@-=!$/833B$?;<'H;!"=<36+5!H/'A6)@1/5:E&#!3F62!A4A*"9?-&G!5:CG0H&F6+*$#E<%FF+#%<9A?""H)&F'0'6&1-4#G;#7(<:!>C!+A08-,<'8&*<4ED9B?/8$)7A&#86D%*A/;*=!7#D>#@>0:>F+%-HE:G)0$<0>:,$265:$$%*E61G@2$:"8);6E<15"GE4/)4)36($$8A61<*A+06238(A@6=B$:H@D!+13!6?B8/B?">%'6423?)3G4FD6!00D@&G.*>,.=5!D>-"#G&>%FA?"<B$<6=%:2C<;3,66C<7=+CA;1E77&#1602<)84+)G"9='5>67%%$4:'*1/08@9$$8$2&-5B/!:"37BH6F!"4./*:;7:H+1&>;9=
@r7911
CAGAGGTCGGTGGAGAACGTTATTTCTTCTGTAATGAGCA
+
?$.7H"-@=8*"'/>DA,4(4<F=D@.7%G)C>+G$9$A.
@r7912
TANAAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAA
+
"%$&+&!$)(*&((&*+#("#*('+((&()"%)*')$(&(''+&'%((#")(*#)(+#'(!&"##"*#)+"(+$%&+"*%"!#$&((('&%+)(!(&+"#
@r7913
GCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAA
+
FC&/:@4G!?1<?C&:C.2(3/E),03/"'*C.2D6B58>'G6?5.=HF<#E':D;.'+4)E?8."5"<%:!.E
@r7914
ACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACT
+
&<FGD.%''"'%+4=52H%./+AB4&=*7FF*:0+F@==B:6&2HE"#HA/)3
@r7915
ACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACC
+
0/,8!6"8$D.F8!90$6F$9<$1(4BA47GC8H96@?*$83,E2'19E8:-0B/6EG2(8F,@7
@r7916
GNTGACGCATCTGCAGGNCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGC
+
-;,A0'B<65&G/%%AC11,GD<42?.!B:%71#/=<<0H6423-D'A;;E$./5
@r7917
ATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCATGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATNCCCTTC
+
?5'>:!H#53,.GB2@:AC7E.;@$9>,8B11!"?0EA;)$;$>H/&6$.F0EC.09>E99@><91%?/FA92#%CA;F&@9>-4?9
@r7918
CGGGGCCNGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGCGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCT
+
*=;)<HG"$%2'%.1*H#*+@/;!#<)9D<";G=-"&*>4F-#2:<:8:5)6HC+&8=9>/#(7,C6FDA6#F-DAF)'"6./;A0.@1*38@3410())'A90=7+(8>H9A/&<C;!
@r7919
TGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAAGGGATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTNCGCG
+
*=BC>!/BH5F4D,/@7DB>(A?DH'D?!6=H!&<.$17'&631C/7&F,E/#<1.5,-8+;E9/B7"'.?8@)G:%1?3+954D"=.4)+,H";6*>=@B;5:#<E-(-7%&98C-2,0.AE9=AEHA"C@+E")2<H??7D::F&76@?@<",)8>-?).>**+4G=H.9D3,+;!%11*
@r7920
GACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGG
+
9C'41D?-16.0)%H:2%*.?85?@=$7C#"9G2&-0*?0&$&#A;)05E'H)
@r7921
ATAAGGAATTATTACNATGTAAACACCAGGCATGATTCTGTTCCGCATAATTAATCCTGATAAC
+
"0')6("9@E5.28:A"E<EA/#&"7;$/:ADA!&@;=B01%"1AE4,?=<!0<=F=B-C6/<B
@r7922
TGTGTCCTGTCGTAGGTAAATAACTGACCTGNCGAGCTTAATATTCTATATTGTTGTNCTTTCTGCANAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTANAATTTTTTAGAATGGTTTCATAAGNNAGCTCTGAATCAACGGACTGC
+
5E;'G$A*?2C90GCE7%))+G>:B?(*&9=$=2?-A&,<#9($?(!(C8CFB=E?@7A#0:,A&;F%69-+G3@(/=&$85.1/<(B<2=.,.*H4=:1"!C=E-E1%G:21F24!),0"A&@695)&?,?'?;=H,!9HD>')3)C3,1?0D:BHBD66DBH=-B7>1B6)@,>6#.&&G*;='H8A$*0>6@=1C2,)D.B!<?85E)60G-)0),4:F5EA)=1EEG)",F&%H$:>89@-?9G*=.9BB?=1E%.%2@(=D4B@1!$;((<86/72!1/4";G&8:C%E<)CG2BG2#.$
@r7923
GNGCAACACCCTTATCTGGTTGCCGACGGANGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAG
+
*"'+!$(#!!$!("%&)+)#+#''++)+&+!#&%)%)!#$"""&"*'"!"*&)!#"&(*++$'!&+"
@r7924
CNANAGAACAACCTGACCCAGCAAAAGGTACACAATACTT
+
@'H%/=DG3$E5E3,#?"?57>..@<!*H>*C.<:6C>(C
@r7925
TGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGA
+
*.!,4-)+1/,2==$<$96:!D5=G<DC)E7C52)-%$''HH1>908!)'C971*5-!<(@<!@!4>8@<3-B0-+?&64*435))?83">@87,A0??/@C35G!D2<E)"AF(:A&+#.<274F.2AB7%4--%'->:C1%('F<;-"69.$#&F$1E1!FH.'EA5+E0,6E1
@r7926
CAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGNTCTGGCTGTTCACCGCCAGCACACGACCACC
+
=?2$>6DF!/1C180-1?5!25EH/'=6ABD@54<++HA5.A=CF2@&1E/08D><A"&;!433."
@r7927
GGTGGTAACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCNCA
+
G?=,A5#(>>6-1,.13+2!?HG/8!=+1>%7E0!A"1<*8:C/<,7>8
@r7928
AAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCNGCATCAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCCGCGGATGGTTATGCCACAGGGACATCGCCACCAG
+
9:$G5ECF5FE/0%:A"?GG=3:=@@0:6=AG=<!@D#(/7>H1,D5A?CD4%(>%:#898D91EE82!$F:>=&,:.$+H;:=*)?8(=CC6990:,6"GC7!)8F&2H+:&A4-F@'+&%>#60E26=G3=58(E5(8B1>EF9/=@H//6DB>3>9&7%!B)7-,<3G((7D692,&/F<8.C36+3;>?/5A.6G+%?4255#&!/#$)D7&!-*%G#CB<95A?4$@.)'D:,+0?0&/950',C2@B,
@r7929
CGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCCGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCC
+
%FA<)'&&9?%13<#CBB"G<%*F>.$=A738C,9:<0$D6-5C/?D8:(?DF6BF':=(?'="HE.#EC'G2@588.="2GD&+E!?*F*-=@FE(?7%4E31:3;70'+CH>:G&.<;3>)-"61E>5;D&6,D'A@<>(A'==2#E,/#F#2@D.&>61%")-*&0'618>1;3338HD"H8?&;9+4:/3E.?(B88ABH'AE8>2=H+:5?51'H7'F.7H=@+';42<1C@2=C8G6#
@r7930
GAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAAC
+
H/"CE?0$:#"(E;15+=*$E8<2*2*07;8%)AH?(&B-)("C"#+33.+4B0"92$#'B/9*<72EC6$01@>
@r7931
CCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGG
+
A":'50?"CGBA0F*>$&4)0$92B7>5C'-%"3&.-E>)DC6
@r7932
GGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCA
+
H*AH$4-$?A.=B.90?!);%@>%-(?A-8#$?7!-A$D,H5<!<H2B
@r7933
GTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGANGGTGTTTTCCGCGTTACCCGCAGCGNTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCA
+
-04FG!6:"C/&/=.=3DB&G?68/=*$E73<=$4&G<4!(9%.,/!%AB7!E$D1ED01;GGF@1>;,@H7CG-F:?.E2G=H%,:&5H)BGEG@";2(5--%)(E&&.C(7.$!/:!F8(*><:<7-1+A*@>>G&G@>-:<-C5G8B++F'(;H@E#5@68*#:)64B(=4H>*&E@9D#E-'4+(7FE."4/C>$%*;
@r7934
ATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGNATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCCACAT
+
.3-'";8B(#0D%;@(!75<DE&DG06>;C.3%A&G)6;/B#75$H?H"G89G%426;3:F(/0G&1)(3=(-@,"513$#&A3*/3$A>@BG:E*G@/H
@r7935
GGAGCCACCCTTGCCGCATGGGGGGCAGCCATTGGGGCCGGNGGTATG
+
12$%F?.(*,#>$?4HCCD(0)=@0'/61(@H3B-G:8;@5E?(>=E6
@r7936
ATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGA
+
?3F+"3H:1<>;*'.5(.$'.',;@)D9&@H*6.G&D!0E$>#4,!=+9@?
@r7937
GCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGAC
+
?>*%#@G159GA-&3E<EF0"<E5++)&?A(B%2?@4!:(B=<G;'4<C(E!5(,0453A0?:#DC+/36:'>?
@r7938
CTCTTGAGCAAAAAGGGTCCGGGAATTTCNCAGCCNGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGA
+
H:B!>%)/0)/CF07&C+/9G;3-83G?CB%&)2)53==A1!F!)(%46F*'=+0C(8!(;:2#73C!254;844;G>@$&*,&2E>?BG'@'.>:6@B91&C32D.,,06/-(31CD8"@":,4H/'(,-='4*/8A%4')+AG2!2%0(><
@r7939
GTGGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCA
+
)&!%+$)"(%$$$))+(%!*&+$*)('!#%(*'&)*!&'%&%+$!!
@r7940
TCTCCCGATGGTTTATGCAGTGACGGCAGCGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGC
+
<%;(6E)E".4F<$0=.193:-&-;H.3"B+1"!$,02<6B0<C82E/,3-G!5E9'*-&5?9"*D(%#?7/?2DF#1,G,E481;D)1,AAB!!#%.;G(0,B>,48A%=40'98397@79(0'4,
@r7941
TGGCANAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCNTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGANTCTTGTCATTTG
+
%)(+"#"*!(!#!))*+*"%%%(&'*%*%#+%+$*(##("!+*#(!+&#('%&)"""'&*&&"%!#&!"'(("("*%")%!%#$+"!%)#!$&*(#+%+(#"$"($'$'#&'#)""&$*"*+'$*"#)*(!&(#+###
@r7942
NTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGGTTGATNGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCNTTCTGGTGNTCCGACAGGTTACGCAGCACA
+
!##+##+"'%))!$%'+$$)&%&%'*)+(%((!(!'#*!%!*%&)!$&#'"!$%("!'"%!&%++')$"**)*$*&"*"*(%!%%#"*+(%&!!#&"%%'"(*((!%*(&(&&!'($!"'##)'#%$$)%$&"+%#*#$+#&)#!$##&&+')"$&"###'$('"$!(($'$
@r7943
AGCGCATCTCTTTCNCTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTC
+
>.(>E0'/D!-&+10(365:HD%,#="0/5.5(DHC8A8C=C;(!'C8"AE>6:H"D9=F/($!5@?,+)!"F+#DA,&A5289$?=EAC-7'4!G;<,*<:299AG<.H335%*)/$13):*B0+97&B%23G'B=,8;&.HC7A#D'(3+0@%BA*F9&D:#
@r7944
CGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGC
+
<+/1!>!#5E/,5!9;7H#""&.<!0C1E%A8%&8?D5C->/#ED8DC>37+'%:B/B(A$//F(3>@52$?E:"*1+H'@3
@r7945
CTGGNGTATGACCAAAGATGAACGTGNCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAATTGCTGAT
+
<*5H@B=$+>(!6BBE;G2#A!7.A=50=$!"%19@#89-031>@G10D$)<=&'$&H=%C*=BA#?CA!?!@
@r7946
CCGGTAATNAATAATTGCCTCTTTACCCGTCATACANTTGCTCCTTTCAGACCGAACTTAGCTNTGNTTTCTGCGATCTTCGCCAGAGCCTGTGCACG
+
("$+"!+""#%"(**!%()%&+""$$&*"#''#$$#'(%!')%!!+#%##'*'#&)*')')*%&"#$#'*"**$!")'###&*'&&&%'&++$+("($
@r7947
ACGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTCACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGANAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAA
+
!DC-??$?0.-%&;3*D"1@*(&0*>51'!71BH*%@:6.#18G>*H9A""%3,*%>3%D$<B'(%9CA/@8C&"B%F(=)2,14%+9,**6:##"E#'?.%<=4:B-*$6658><2?.)A6;9&HG-=@2E+"@9*!A?=?CHDG6G?<-98+#A'C??7:&>24CGA?2*!88,;3E+:+!9)?*2))(2D<63,9:<8*->E21HH29@+CA;/&5'/H%70D#,<073D/8".0$"!>
@r7948
GGCCACCCTGCAATGGCATATTGCATGCTGTGCTCCTTATTTATACANAACGAAAAACGCCT
+
);!B()G+D?GGB,F*57CG>C70+*"<H6?!#FG-9#GA&8>3%$97!"8B-=>2BH=$G?
@r7949
GACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCA
+
E'D@H*821&/*FHGD@B5H%A()5(0C2=HG0%/>&(/)5,!.3
@r7950
NGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACCAGGCGGTNCAGGTGTTCTCCCGTATTGTTGACATGCCAGCGG
+
!9;2%2!87?6F*@:="&(E!H:,25-D6,(.;4(;0/6>@E1*4)38#:2->E3<5GB;06%=+0E"0-+37+F51F(CB
@r7951
CAAAGCCATTCCCGGCAAGGTTAGGAACAANATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGC
+
B2A->7$!6,-;!=AF:73EG+GA90"#A07=/3%80.B/$'6@/5G%7E$A!)4%02$<6,&6E?16$@;771)9A>;+'+;($+*C9&FAB/&.E0-!>DB)!6BH%CB2EC05/?GG!)AF847*@
@r7952
GGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATNCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGNTTTCTTGTTGGTTGCNGCACCATCCTCTTCCNGCAGGCTCGCCAGCAGCGCANTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCG
+
$BAB-=BC:$1!,!076;HH60=#(7,)0F:?2/)/DG:()**G4<"0./GD()8)$5%E@"A,)*1(34D5A3&'C?9$/&'.:(DG@D(0G8*&%H)"<"==2"0H88D7F9*A#,E+9'C6)-$:*.EG1D72?$F22D4C:>31>F?H*$3("&"4;@E3A-
@r7953
GAATATTTGGNTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAAT
+
2;H,,B!;CE$E%H4.+H*8/5)B?%62&?%?5@-*;9>#+$&?'(G:4FD%B%:G$)6*
@r7954
CTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGNATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGT
+
1=A/B'>C1+8@22)."9E:BG<4/#;,-<:8@=#A"?6;?@GE(&(/=7&.H7&=1"!(H@+7.C,+"533&%CAB5"%"<.59H6FD>"02;$*C)5D:H36EA61C1G1'',(90(CAB3#81!'H@?2
@r7955
TGATNATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCG
+
+"1</*#8<!1"B7;-0$*?B4,"#-.)'GF3)G#!)@6@+12'?
@r7956
NGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCACGTCAGGA
+
%H"/54C%/!72E+>@'$@E<A01504AG*-F389<?97'?4234,:+/++1H!/B$E?#FHE%+=<)9>?"H#-GC'/E+3%%?H*4D;B5(7=!(9=A9-G;?D
@r7957
NCATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCAC
+
*/BB?;0=D"(+5%5D).D4-791=:,.C9*2=EF,*B?(GF!>@8)$$4(1H9B'EB94&9!#3$"-#,&-6&+89,C5B+)&>BE:9.>.(@803)$AB1H0F=?4A7'6:C?%3
@r7958
GGTGACGCAGATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCANCAGTGATGAGCCATCGTGGCATCTNGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCNGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGNGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGG
+
6=),$HH,#;F3BB2E6+'A!$A>DH("+E6-C"?4A';!%H$#G5%&63*3-?.>49?HB;2$58,?<-;-2H0G>B3A#*EF:FDF)?%G911+.B"C%"@='.F+*5&80'D5#=0B43()4("3F5%4;"G-(>38'F;4&;!23.>B(@?A:FF.%$B<0"7C",)0<C&):%,CGA&F!"E(9>CDA=*>>!$2.=/D*34#%@)7!B9(-#!/9D"A.-C;/'4<@A2C%11?2,B97BB,&&,2AD*"$.8)7!A?;D0?G!$<<CG=*1);7?!7G)<H>@C98.6CG$@F)2)-
@r7959
ACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCNTTCATCAGTACTTTCAGATANCACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCNCTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCC
+
/!328*8,D>5H#+&32">/9F"@:FF@./"##;4=E&3/D.-:H+/8.E#:A=2D"-<B-F$CEE617'?#G!'>089,C00$%H(D(0/3DF4/">;@<))0?$:326$1C/<H1*E$%G-02#)@E1B@*/"C),:'!"7:HE-'43=!2,0<')G"-.C17!G=B<00/><C;G87($92!D&.-+&<63B<C,A7;2/-8CE$A3):2447.7*,*?C0439/'%)4)-F2>;=*3F?9))66G+G#:.06'87/%1@C=C$5!.**",&D-C4&E$?%=(34AE;<-)4-69FD068EC)(%&D#?$*&13!&E>6D*+=56F:G%,:,2#@H/2@075"/BG*6<:(7%(-&(C/3;D+01:;7&@0;FBE=G<:!"7<1A+7/@&<920@E7+2*1',6&2518C%.'4C2A<(-
@r7960
TAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTT
+
6E4.DC44E+6@1;8.7H8+954!2FDE95@C%/D1+!.+$,
@r7961
GGCACCCCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAA
+
<42)E.)!=,.%H"?(.+8B+6;@>E10!H5>63:47G"H,/
@r7962
GGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGTACACCCACAGTGCCAGTGCNTCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGNTTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATG
+
;3=)49@<%9'8H15E%63;5;).CC3G3;/G,=:(#!%9DB:!8";-3+>&EA1.D3;5!7E'2.$=+*7&A$?27)4HE3'B7!-2HB1F3"#,8,"#7FF(&:.!4:40,0$(G,H>=(G'-5(?E-,C2,<>2--!!-!28+>2:148?>A98-9HE)1=9E$H3:)<DC;!23A,!D;A(F47)(.750:D2F.?C*@%CG'C.7#@%!1.27:G!B>=G(<C!),09.8!A43'$0'/>7298?9#<8=%1!73:?)A-F>7H;5,>CB;8
@r7963
NAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACCGA
+
.!:4H1'%-008A-AA6<G&$&9E49,1$4D8****48)74=+H##<0$DD@8)E&!=?C630$!)!.>9+6H.>0-!*=CB2&3)D7
@r7964
TGCCTATTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGT
+
;E'"D>+#G,9E"50'#?'+F#DG34%#:C>!"A/=(F&9@70H99#5D@7HBE@9C<*+$"C>-B.4%(,7!7.4C917'5-<;7?'7F3#(E6<($>&$")B9E@#0+C(EG$>"/73>15G6"=$9"E,=G3/28$4G="
@r7965
CCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTNGAGGTGATAAAATTAACTGCTTAACTGTCAA
+
CAA2".3?#.!<36B.=E)!618.1*%9>'F5=<'1!7H>HF#H!9)>E-!$CH;":=$323>9&>+"F<57'A!$+0&H%66'0CH-)A1F77663
@r7966
GCCAACGACATCTACTAGTCTTGTGATAGTAAATAAAACAATTGCAAGTCCAGAGCTCATTCGAAGCAGATATTTCTGTATATTGTCATAAAACAATTTAGTGATT
+
:&E&"9-/<?85)D&)?.(D)/=@7.E"H8?B7134G6EF)-"(>>!4+&F<)#E:B@D;<*@D-%@#-A'+(>1,7=03$)>81?,7:#<;&A59$-8CB72!AB
@r7967
TGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGA
+
&+(!)))*%+($)+)(&(%+)"(+(&"!(*%"'*+(&!*+"&+!)'*%#'!+&$*#"&++'"$#
@r7968
TGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCG
+
*FF>D-@!,!+4/AEAB:D"#90*'9=+!904C40=(&<B95D@D+EH
@r7969
AGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTNGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCNGATGATTTTGCTGC
+
2*""1B1)!?;C*9.HA-6$/'831?(H/ACDA%&/36.&C6@+.>*&.F/C"H&A-)8DD;;DH><)A4C:G)<B8!.;H:D:%:BE-+3"-2B,A9/0*!C)&99G4/+:3A*83@9$H2C:.2$=$978+@F7//F+%2:"1HB
@r7970
TAAAATCCATCGCTGACTGNGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTC
+
?G1.F9H!B8(31EC@BE#<=$+00?4'+:F!FBHHDE6#&*=/+<567%3'@EH?36*(+.4H"AG06-88"33"6=7BH:8-7?(9+"46#?F7G.E'%36>;2F&-2(E..69H?8=-45F#&F*)?0G/B<$?*1G=4=+4E14(**F?G,'0*"*&*'=,4)$##0H(>"7!"9%-,57A'8D'0?:31#--:C*40D,-?(HA6D
@r7971
GGCCTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCANGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCNGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAA
+
9&DAF3#><B$9<!328C-ECE&2*F.>;>=!?<1:$$,G;B3<G;A;$*%<%&("B(,C#.E()3G1?3;%*-.(A;25+%E<-E$9=F=631+28)=7D&D?FH=(#BCCE?$/#H.*%)H-D4"+?,-*=BCC!7BD13-6/."8'>:2B1.%,3&96!GE!+*?C%#:H50?=24H<<,'.37>D,E4;;;0#E><D0+6:1%82-F6$&'9,,#F7<:#,B.+F,E1B,F9-"!)F;2,6;7!!2*69A.74(
@r7972
AGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTNTCCTTAGGTGAAAGCATTAACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTNATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGTAAAAGTGCTCCTGGATTAAGTGAT
+
/,:=4130@B;-9"<)$C@;,F<(7C8,>*$&@./=,>$2,%+9"2B*+!H@&5/5%841CHH</E5:#F30()69'040-&&("9,A>F'%0(")C,(4"771HD67HB.:.C./6$@H'(C)*$<)<(/BDAE!?0*F5-E<;GE@GE6>17&#1,+@,9"3,@2H3878#94:G#,@GD?##>6*A<,*@654-/76H26$$!''#6#>:AF"C'0AD(B7,&A=7$.F7A(F0@-/6(C#*&>>88>5@$>"6!74+4:7#5+HB/"GB"4?+--,0>26/%B',B$E!=/6@C';+5!,5!?703G+3!0*?G&??F<-2-H4A6,*)0
@r7973
CNNNATNGGCATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCNTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGNATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGNAGNTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGANAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGGATNAAAAAGCTGAACG
+
%!"!"*!)!$&+*!)$"')*$+#&#"##'&%'!$+!&##*#%+*%$*)++&$)+**+(+%!&(+)++$##*+%""$($*$!%$$**)($+#(+(#*)"%$((&!%+*#)$!(*$#"&%*#'&#%""*$&("&(*(%)"(((($)&%!!%%")(#'&%#(%#%"'+$($$##)'"$*&+(+"')%+'%*((%%('%(%'''&&'#%"%)#*')#"$$$##!"%$#*)+$#+'%($+%+)%+*%#*((+*#'%%!$()$'&''&+!*"*+'$$!&!%%%&*$)(*%+)"#(!)*(%%$%*!*!'&(%%*'&%)+%&"#$"("$&")&!)+($"*'#!')'$(#+&*%%+!&!'$)$'&#(%)*#$"%#*"$+$$")*''$'%)+&
@r7974
CTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAA
+
'99%!AA8=.2'?-C%9*)B8.?@>6.>0:D**.3;1255FB'@D9/4.9DB5B6'&&"FEB2>%
@r7975
CGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCC
+
34-(80$3<HH(("6/@*=G9,8+GD4-)%E-$!4%9=5B*79
@r7976
GNNGNCGNAANNGAGCNTNTGNGCGCCGGACGTTNCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGNNCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTNATC
+
%&$*!'"#)%!(!*&)#)&)&'%+'&((+))('"!*+"%"*'"*"*+#&&('"%*%#$#'%")''*)(($(('$(&)*!)!(%((+(!$)(*+&++!!!%!!$'!&!+$%"'
@r7977
CNNCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCG
+
)&%=6)*BG(3;#/E"3%&2+.F$'?EC</&7794@9F";>
@r7978
NAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATNGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTNACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGNTGTCTCGTATGAGCAGCTTTCCCGGAANTAAGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCACCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGATACCTTCAAAAGCGCGCATAAGAACAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGANGCCGGACTGAGTACCTACGAGAAAGAGTGCTCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAANAGTGACAGCAGAGCTGCGTAATC
+
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
@r7979
AGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGANCGCCAGCGCGGCGCAGNCGGACGTGAACGCGTAGATCACCGCAG
+
")B&EC5"=B#F"E(!$)0C;#,@&FH%)D9FA3&GA8A(?7D5;D2@HA'D'B&#7D;H,7<&2$)%6G19@-2-,%G6%-@A&!:
@r7980
NTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGNACACACCGTTGATNATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCC
+
&+"&!$#)&*+!##'(&#'$+%+"&(%#&)$'%!($%#%++"!!"&!(#(&(+(!+(##!&!(%+"*'!($*'&+&!)'&(%($$&$)!+(!$**")&$$$)&'*"++*!!(#')#(&)+
@r7981
ATCATGCAGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATT
+
);2B3.2.#16B>B$4<,'*#-8$>7*5;0(.CB%&/DA/'6(F4F
@r7982
NATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTC
+
'#?:D>0/=,7(#G!68?-,F%,=C0E2=)BB=1E81=8.%A.33A;%59=:
@r7983
CGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTNGCTT
+
>7*;G8?=E,0E/<@GGF"60*?A<?#10*8<1=F.?E/E%3)"@C<@2$3@:?;CE:HE4))A
@r7984
ANCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTAAACA
+
%!%+#"*&)'"+%$'&++("%"+$&&'"#*'!%!'!&%"$"#!%"#%+$)
@r7985
CACTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATNGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGNTAAGGAGATCAAGANTTACGGCTGNCGAATACCTGAAAATTTATCAAGCAGCAGAATCATC
+
$"(+"'($)")&'!)"($"(+"&+*#&*)*"+'*)##$('%"!'!(*+)&%'&!$'$$'(+*&#%+!*$!&#&!&(+&!'"'&"!*)#!)#*"+!*(''#$%%"")!)*$")%'!*&&$!&##'$#("'$*"+*!#!!*"$*!()*(+##""#''*!''$$*+#&$)&##+#$(+!#+()"'!)#"$'%##))+&+%&$*&'#!&
@r7986
ATGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACG
+
'+76'14:0H9&G;<D"'6:!8?/(.H&@<FB.9#7A1=E5>!"E+GF$*0)6*6#;<9>B(.>@F)CB2D?
@r7987
GGGGCAACCTCATGCCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAAT
+
3?:B7AA2F"/7;7?$@<BBF@)CDE1'7069"*$<E'B%.H4"??>>>>,289%7?$.'3A5A%B3"!A,<?
@r7988
CGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGGTGATGGCGTCTNCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCT
+
78A5#43)F?G,D"F0CE@4>22'-6&<7F9-<AED9.=#E3"!.0(/*-,%@5C9E%A)=>4"A/,G3E>"06C@D:5"1-?(D,+BC>5/<CB&17$0:"#6%8*2<@ED!>A7GF6G)*C?3*A!%1:
@r7989
TATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGAGTAATTATCAGGAGGAATTATGCGGAACAGAATCATGCCTGGNGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGAATGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTT
+
-*C5'&#">4/0<.9"@CH6(+=H3(0&-+"AH!'>)1:+%A8*<7)?)%64%)4B.;9%@*-)7=9/C$6/:B#B=@G'3G/F=1@ED5$"62?8BC<=!#-):?"F7-=.//-5.**/50(G#+0!'51'@4):1$/*%)/@!-78:#"/=CB84=3?05.&D>#?22AF3E<,D/E3'16!&$7"C@<9G-!0&95/"'#8%=14+5DB3:=B6)2!=?2F,0*!?4GG,97E6H5F,0#1,4.('B','?EB(H#8%FE/-!0B7#3&0D%E+?H3=,53-H')9B9'CH$FC*?6&$FE%@&"3>GGG%6*&*G7;!11?$@H-";8**3@8);C>-?>H&(E<&FC:;A5G8(-B*$(?)
@r7990
ATGGNATTAAGTCGTACACCCACAGTGCCAGNGCATCCGGTACGGATTTGGGGACGAAAACCACATCG
+
#*'%!'+%$$%&!+%%(#%'"**$%&)#"!&"#$+(*)%#(+%"("#$*$)#+%&'&+')&)")$!('
@r7991
AAAAAGAAGAAGTAAGCACTTATTCNTTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTT
+
!+#!')"*%!)("#$"!)&)$("+%'*#!&""**()##%++%'&(&#!(!#$&#)*%'!#&($#%++)'##)(&!%&+$%(!%$+'#'$%$##$#$!)
@r7992
CGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCAC
+
4!)5F@&;D'9>/G2H1?/F"H7).H6!C'1==?H*+'8,>>4(59-11.H&G0-=
@r7993
ACGCGTGACCCCANGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGG
+
DBC/;B/4/.+2@/2,H@DEF&E*GE.H<8H8"E-;=?5*?<47<E<=!#+27'1
@r7994
TGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACACT
+
:&3*3.@H32:-(@8G$$5810>?8"D.>F#F1HF>6"D(FBADC#),63D1G/'>$*G@:9',!
@r7995
NACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTATCGCAGGAGATC
+
!;"+=:1=.C0.3'A.'A:&1*&%>.,0)(9CD!BG'%79;!@68$>61*5.90E9,(@%A$#H"=*;$&B8CD-D%%0)EF6H-G*+6DHH5A9,-63>'9/&1&HG*!47.#H53H<1H".H
@r7996
GCATCCCACCAACGGGAAAGAAGCTGGTANCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGT
+
(4?"'G#?E'6@?)#/2B,;<-F-E6D;G0D@F+7@84AFH%)=/%81*D<FD2@8(-BB8.@0&0G?<;+@@/E%@.(E4#.9@.@6E(>"!)
@r7997
ACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCA
+
(/A>-4+@3667)&E:D678%-2+GC&3.3>F01#G4A%0"84%.&(9A7076C)?CE7:*.8=;!4@/5H54/<AGA5B$=!9A68'%>&'HF;=2!F;25E#5-78,#&)93;'
@r7998
NCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCANCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCNCTTCCAGCTCT
+
1F"B1+0.'(#E>?@*5<@/+3-.8'*;FC?.:(;>)2A781F55=8>>5A?#1&9EH64#<$&/"E*("#,$27-B"H-&-H=*+A/*?:C*5B!3+?-%5"F2>7:/<)4?,**(%H'$DE=9,0+GGDD0$>!%:3(/8CE,#E.$*06G070
@r7999
NGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATATTTAGATGGAAAACGTATGTAATAGAGAGTAA
+
'):.7@A..8!?AFF80057E7,'4,$</C)FC6"'@>5?F%656%3"C2%(*9+=C8":"94%#*&*#5;?-@03F
@r8000
CGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTCAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGGAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATTACNATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTA
+
F?'3G&B3@-@$?HB;:%.,"?*,*#("4@+%#.!H-;<?EEAG=#%B(2?/)<:2EG$9:!70+>4@31=0G'7E(B8G&&8F#.BB),E%4G<*83;*'#B-':3!F87:/%00BF@8;*A3!%<;)#;!HAG520@&()#A7.7@HA$!;'8)?35H%*,7>.)7+?2="0?,:"4>&99H&'>999?;'C:9*='.A1-C;=H#;!D36;747*=CF+$=-"-:,!D(3,B*6@8B%(E!A*7$@;,D6>>DEH?1><H&:E'44DG(=->G/ED<&>1*$3(4)!"1":2C>4>)-HGB3HB#,A@E+EC>.G-?H,>2:+/.7.,@>.F=-<8/3%#$1*0#7>:)/@1@#H40A&(3@!9'F/?/5-4>'FD!",@,DG,!ABB%)552(4(<,=+:C<A9F=EGB20H29&#>8HD26((:D'(*+;2:91,=G$A+;"HA2;G2B,0A3D>C-44D%'?:)0-<;'"F:<9CA"H&:#+E+',4#/,!--
@r8001
ATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAAC
+
4!F29D..F-DB5G)G7;A9?1D!BHD?>1<,!:-!*'HB'<$&F%11!
@r8002
GGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTATCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTNTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGCTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTA
+
B)-'&E*3,!:!?B#21>A/$05*DB/&,,=,.<A;:)G35@6&G&=/HHH()7+"#-*"3?*+1CE?&03F3/.&A>/,%516*4EE6+D(89!D#5+5-G$1B$8#9.8+C1C52A&C<)4%=6/%G*+E;*9<H(39'&8#;:HAHA,14=>24"9)-9&@%E(1H(/0;5D9;4E7=?2:59@31'3H7787-./,(9<":C,H."4E768D4;
@r8003
NCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTCACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGNTCTGCCGCTTCACGCAGTGCCTGA
+
$;%#<;$5'!7;1$*7(2,%2+H<0()1/"#4.$6<-!)31=<<5,0C8G;/72$?"9C80DF(!!*%7871+#/0#-0:F?2<$7=7$=A-B&;#,!G;B;%.)C;+!)EAC@@8
@r8004
GCTATGCCTGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAAT
+
*GF@25"$BF)'E%CH52?7FFG6>68A@9$(1"3&C%0+4&&%:(<95BD5D;G8<7D7!>>=8@;1,<,:5:1/4</G#1<E%A4'A>"C'86"94
@r8005
GCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCACCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATNAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGA
+
DHHA*47!/7-G%C($H0AF;+A;+D,B:;.(28)AH@1;=F!.B)G#E?;53$?5.::0*%3$./D*#.30!CC:4A9="-6H"GF:.;,869%0.6'$$/(BG)(,-2#%'&+0'/@6&75#&=;/GH<&499-).,--1A!!3-F$G:'EEB?>!+*<3@%E!#(7C7A("&;4()2281@:8'"A1,&@0:'))63.41>(:AD>48<B$1+!'%)2F?,20:4-23E7*=+<35?>B)=;G6&0$1FG%4-'+%)38H,-610<+9276E+3$.!0!'D%>(G=8@=5(6FH!9CEGGC#-4$8(?A'
@r8006
AAATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACNGAGAGGTTCGAAGTGAGCGAAATTAACTCT
+
1&GA".&=6,#:/9GG53E)$&A>0+(G;&<#3:D(G-3;4'2-&#;,#--BCB809A=?27108?<4E5)G.D33)>E,-"1!9,:>03HE-=H:;=*(@&4)&<:-H!'9@F38*0:/>(C?9<1C107F4:*>%2"8$)?,HG:((=#$CC9;(+/A1=(=4;>;:'.=00*:*2"/D#<B9+H!C=7.?+&G6A!F'-'#F>8F4
@r8007
TTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACG
+
G!);5,5E721'/E/5,.F&0C#3;FB<.?80;2F-BAC9+")89$2.6C(H2H0+)1A>$6"2@70,E7HH17G
@r8008
NCTGATACTGTCGCCNCTGTCAGGTGACCAGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAANAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCAC
+
"('0A"&<)"%C2?6*6B#'"(@!0,":A2C/=<H'$.=C3.?H35:1(&1'&4A?C*9&391!$1'=1-A;C*!8<:%$GG+C4&)G1/2-3&2!C("76'>,B,@@@66"<EF186&"G7/&69?2@##'
@r8009
AGCTTCAGCTCCCNTACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCAC
+
/<!5B@$0*8+@9=,!!(5>5F!/>3B3?!?)3<3+&!?C&8$B33A"6<(0-
@r8010
NAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATG
+
)+%)!&"$%!"!&)(!""&%#+(!('*(""$)()!)&"+$#$#*%$#)")+!)'(
@r8011
TATTGGTTCACACGGACACACCNTCACCGTTAACGCTGCGGGTAACGCGGAA
+
261.79$#:3>><%,%G%+4B#678;5?!E$7-5#D";#BC93?8%/@:%'+
@r8012
TTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATAAATTTATCTGCTTGATCTTCAAATGTTGNATTGAT
+
5!).%BD"4A.$AB6<-G4@GC>!"G')>4@:,=E!2<1?B;@=3H*%0G))(':0A67)4,G6;H3?+':=G9D):74;?:>9E3!(":%F05+-CD(;19<@BE)2GA8-EH78H.?/"B=849>;(421.1>G-977G'-EDH)@"$+C-'+4</1-<$)<75+1>4@?
@r8013
NGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACNGGTGACCTGGAAGAGTTTCTGCNGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACANCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTNCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTG
+
":G)8>3FBF-#21?11:?!22F)7(7#!%$".&'!:F:4'',5.06,9.+B-FG*%3&21"@&0011<(.0+)=:EG4/(G04H54(G7)'&?2$#<632"<C,0B'%&7H3BC7H<.F1B=0H":30E6)F!6;58+-E(%8.-+&")<3'?30>+7GHA8?2=!4AB'0BE2;.D'79>HFD/3033:A0$'D'759>?%"&&09C8D!,:=7-G"+B@CFF(D<"8;%18640:<9&G'0@B
@r8014
ATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGC
+
B+<4%9G4$"33C9H-<:CA/<)=0@8)?E,+0>GFE96)2.=*&BB326%1++%6+;5H&7"<&1;#CG&%5305?!G1E$!7)
@r8015
TCGATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGG
+
!#!')*$(+)&&&)*"(*"*'+%("('*#+&(*'*%(+&&$+$""%))()#*"$&#+'!
@r8016
TTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCATATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATA
+
3G/"C3H4G8:=C&A7D*/>E384G@>'.E8<D?6%#"'0/CD1="@7&.&1GA*&H6=8&?547,:8':E6-56-,'G3%4*H;
@r8017
CTAAACAATGAGTTGAAATTTCATATCCTTAATATTTATTAATGNATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGAGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTAT
+
2*=,#;B*>?8%=CE?G73?97:G35)3+,.*=4(9$C93(':9?+9>"&;F&:7/&A3&?,98$:D:CH-697)$4$$?$D?+#9'3FA?!#>5+0>(FG#5E:$9(#E8126)3@-H(<$HF;D'#>7<:3D0BA5$4E=6),$*'44@81+/3:8924"1D)%'E/:*.*?9
@r8018
GTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGANAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGANAGTCAGTTCNTGGTACTNGAGGAGGCGGCGCAACGTCGC
+
(6:C$5/G!G78,-<G2&$+H%.7CE$6A%!07*3!=D95#2&9GC@#?!5##%DF/B!3&=EF;%&H%<C?<(F;!"/.CB864)=&<@E1&:.:$8=3$<7H:6:!.G+,9FG'>9<(D@*1/'!B76$E@"=4$.'A
@r8019
GGTAAGGAGAANAAGACTTACNGCTGACGAATACCTGAAAATTTATCNAGCAGCAGAATCATCAC
+
+$"&('$"$##+'')&$$!)*$!$*#!&#()**&*)#$%&*)(*'$)'$%+&&#$*!'$*'"*'&
@r8020
TAATCTGCGAAAACTGCAAATANCTTCCNACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGNTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGA
+
:<@F-!+'5'."A98:CD':758+D,4)<H"AG<$%29BC5A3*B/)"<F>F!;'===.45'@#G8."!>>!2)GE?66A==06)'28>-8"3$'/5:0,,5H03'F62D71#?(B920C!3963B>4E9915)6)11$>3--)"-?E$,>+)81A5&'279.?7,D;=C2:,5=(GC"@
@r8021
NACCGGATNTGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCAACGATCACANTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTNACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGGTCTCCTGCGAAACCACG
+
#&*$(+%"$'!*$*"(#&*"&!##)#!%(%&%()#&!(%$((#$+''(&!!(#$&#+'$((((%)%+)"(#%"!$#!'*)"'!&*$!!)*%*%(*!&%*#!%"+)&"##)!%!!+"!!!&)!&'#!#$%!%%%"!#*+'*%("!$&+&&'%%"**!++##)"!!%)#+*)#)#*$#(*(%#&*&")'&("*(%"$#++*##$+*"'#%(%+*&$!!%)'#&($!&)$!"%"#%!%*%&!&*"!&&'"!("''+)%$$''+"+'*#'+))!&!#""*'"%##))+"#)*#&#!#')%*#"#!$*%%)'%")!+'"&&+
@r8022
TGTTGTGTATGAGTTCGACTGGAATGATGGAAATGGTCAGGAAG
+
F:>*"<E>2E.9+H7:D(3CH)G+98+53*+AA"$7(GH/=>%<
@r8023
AGGNCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAA
+
CGBDF=@*@'#.*+249/39=<.#%C*:8E,7A01:/G1!>)1.
@r8024
ATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTNCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGNCA
+
2&E#A6A9A06C;A60/-?#%&H-B)18'&43/:27;.0'(.>!%7'@A@+"719?$?@D2+5"4"?6H!>6%F+5AA4-&#6=?*6&4
@r8025
CAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGTCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCNCCATCTCGCTTTCTACTCCAGAGCCAGTCTCGCNTCGTCTGAC
+
08C71G#H8*ADE,$/'!$C0/"2&%,0F7&EG'12B48??3:",'86AB+$7=3G#6<?&@C#*+>:=>?263<)C2,A+0$>+$2$(/BB3<-D4*/;2;,64@?+3.C>#1"B,.45%E!::,7D='F2/E+*87/2)=;5:!'&6#D:;FAH>5,#8=""D2';HG/B.=C#6:?+,,))99$1+<DA>1/5:D))*#DF%@E=$+G%
@r8026
GTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACTAATGGAGCAAAAGCGACGGGCAGGTAAAGAC
+
/&+9H5)3!<)B#<$=G%CH)=5#=<-#G.F@%6,F(7/4@!D?:*G9:AF?6;H%;:8?$1A*8E.5/)C4
@r8027
TGGGGACGAAAACCACATCGTCGTTTGATTACNGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGCGGGCTCATGCTCACAGTC
+
F,EA!<HA.FC2(!)-!-+E5.:0>:1'(:A8H*$7?.!#/5#'.-1E)""4,?%-!4&>*=283-<692'8E9D%%3ED75CC/,7A%>HC(.E/4C48A2#)+
@r8028
TATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACNTTTATNGGCGATGAAAAGACGTTTCGTGAAG
+
'7*28>-:(;F1F*@!&17F979?;9"82F39E,E27F>@0%3"0E&:5*32+<G"7;$>'9&$%5H+5;343H#&H9!"26'!>*E9/(,;EHE1=?>3/G%12C5>:$6/*D
@r8029
AACACTGCCCTTTCAGNGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCNACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGA
+
:@.'H<2@G"/9'")=H&8;4%F70C55*+#@0&H<03H2;97(.)4>E//9-H,B:2:<>E#4??E<#,&8=DDG03838CC5-E!3/"%@2+?-:.*0:(DC<*C+=&DA7$-$*3,7AC2&#G)0?$E;/F$=2%1.-A:+*45?H"BE3!&CC=40&'"B9<6D=*%A;F"74%85
@r8030
NGGTNGANTCGNNNCNCGGGCCNTANNCGGNGCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAG
+
"%()*())%)#&%!$$))#"*!!!##"$%&%&%++$'(!"+*%$$&)&&)"'#'$$%+*+*!*)()%!'%)'(&')"$)!+
@r8031
TTAACGGCAGGCNGTACGCCCCGTNCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCA
+
2D;#=6$=HD)!>C7),-@251F$>F(B.1&7GA;G0+6F!5;-$E8,?4=@20&:%"&9H4&67.9&*+&:<1&6;.;GC.A.F?5D9FF=*!7/0?%H6D$A)B7#)#7E2B+*0)0$,)<3*B3(8/.0D4+0:!8!DD#15F"B;AH-651B%B%F8$6%C-",
@r8032
TTTCNNNGCNNGAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGTACATTAATTGCTAGCGAAAATGCAAGAGCAANGACGAAAACATGCCACAC
+
(#('#$%*$#&!**++#+$))"$%!"'&)'))!++'%($*%&%$*"*!#!!&+%%$&#!)!'#'!&%#"'("+("$&&*'*''%'")!)$$(%(+##)$'#%!)
@r8033
NNNGAGNACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGAGGTTGCGGCAGAAAACAGC
+
$%#(*"$+(+)+&#)((()#)+'"#!#)"(+'!"'&&!"!$)+#%$&%'+&&&'""))(%(&#!#+#$+'$)
@r8034
NTNNNTCNACCCAAAGGNACTGATCACCACTCNTCGCCAGACGGCATTTAAGAGGTGATGCCAGCGATGCGCAGTTCATCG
+
"'("#)*!***#*"%%+%*!+(('+"$)#!+(!'%+*#!%($&"(!'+#++"!*$"''$'"$&&($#+%$&%''"&#"%%!
@r8035
TCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCC
+
F=.F@?=)*4A%>.7%02#27B61;7'!*3@G;=>1*.,@+227,7#>,+9<#,=;&C;C$5?6*2:%*A%!;G=G>!=FE>'G2BH7=6
@r8036
GTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATNAGT
+
>.3H)8-18D6&*EH-@:*:586355;)HH(/55=%5C;F>@#A7HH4':87/&(@28F18,C,7#::E"=305??,>4:D!?DA*#!66:2@"+.,E>&3HED#7
@r8037
TGCAGCTATTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGA
+
.,)0<#72GD?A=H?A(A::1>:)#--+E=:,@,8<8+#+3FB0.'6.-H
@r8038
NTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTA
+
$=G;E'(19$519#E14H$BE+"1+D(!5CA(B36)!G-4F#5'3F''%#$
@r8039
AGACCTGCGTGGACGTTATGTGAGCGTGATGGNCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGNNGGAGTGGCTCACAGTCGGTGGTCC
+
;BDE+3-7!/1=;4@A2@:.0",,/E<(F)52+,C91(>0">#B&!5#33)@%F<:@*2+!<65%?$+<&-G,(B!699E0<%.-1+*.B2+#.7F@&=?/A;H2'
@r8040
GTGGCGCGTTTCTCCTCTGCATCCGGCGCGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGATGCTGACCACAGACCCGACGTCGGGGC
+
:+=3E!9@?E7E1FH@/*!B,7B0(3GG(-==1-=7+.:(:'5GG#?*"*?9B&6"#>#4!/(:>&-(2@H8GA8(&6*-DBG0H/-A
@r8041
ANNGNTTCCTGCNCCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCAC
+
%'(('(%&($""!))*+'!"'*($$)*!(*%$!"'*"+%"'''$"(%"%&"+&*+$%*(*&'%
@r8042
TTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGNGTACCCTGTTTTTTC
+
:50-C-,;AF1</?":+;8%E5CF#@38?<2#F01%.G-!E#8E.'7&B=A+?HD933G:)@6<%H//408'%$0"*01A6G*9(+0.+7"5!6'(F25,C<7;;(
@r8043
NATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTNTTCAGCAACTGAAAAATGGCCGGTGTCATGTCATGCAGCGTNTGGCTGGGAAAAACCGTTACCCCCTTGACGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTNCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGC
+
"6F,5HC1:)F#,EC64&06>HC'$:@.&$?B44+0?*%,0E*'@>H5'059@;D#&=%.??B*3=>/&/'>=0%95)D.@-;8.(A0H@4F.4%:GCD3-8!.7EBHF%==3<E2864B"F5'E270%%!$@>5=&9;;44!+1!+?<C<D:237BD789>46D2+;62'#,*G>H%?6A2C)EC=$%E!(<7C)-=38%.B(6:>?<;'G3+B8?<9#&4:-(+F:!-74&B20.0@+:'!;E"@9.E-#?!9G4,.?59?#&*0,.9G(D0.,=2+H0"DA11,?.B#%?'186!CE:0EBE0C1@:*2/C6H$>//.1F3/A&?'=""5)"D,->?
@r8044
ACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCG
+
=86+("<-<79E1G@#$1=?(<'(A4$0<"H+4B@($/>?F->4051:,CD$8D
@r8045
CAACCTNACCCAGCAAAAGGTACACAATACTTTTNTATTGGACTCAAGAATGCTGCCAGCAATAGT
+
4$#A!!$:E',3?<..HF)69+493E;'!GD:$%EGHA/-++2+H'#%*9!'0%#A%@#*/D9G!;
@r8046
NTGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCG
+
,H76D,<(:78,>>---2861G1,GH)@%7&&G+=4"G&B:$+?&#741?5G*9#
@r8047
GTGANGTGCATCNGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGNAT
+
=:4?-5)0/"$=&F04*@G08?;6:&&>@904<<=>4F'',-E'$6(2:948:?A>CE@#.!:&2F82A7(<!7
@r8048
AAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCANTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATG
+
81#F<*D;$3=&:!;627)4+:4*+1B:+4!*E)1%;F0(!:-6,/$FEC2,F)*,+"F(7C;);!5/9D9<(529<D)/G?:B(3,0/C7A4F%=A8.?>BH86CB,..C8##-GC-H+%GHF(4-.-B44'!H4;7%B//."-)6@0!8HBG0.<?.=8#+/B!C:HG)4F914<*-61=$044C=5=EFH,.+D><H7G;
@r8049
NNNTTNTNTTTGTTTGCACGNACNATATGTAAGTATTTCCTTAGATA
+
!##'($#%+$*!$!'+")"$!$*()'!$&%#&!)$%")#('()*%'!
@r8050
GACGGNCCCCACCATTACCAGCGGCGGCNATCCTCCGGCCTTTTCC
+
16A!20;'<8-6@4,+C@C+&/&2D$?H!D*.'"(/=H/AHGG,;E
@r8051
CAACNNCTGAAAGCGGATTCGCGTAAGGGTCACCGTTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTAAAGCNGGCCAGGCATAGCNTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGNGCCGGTAGTCATAGCCGCTGGCCACCATATTGGTGATCAAATCTGACGGTGCCGGGATATCGCTCATCACCGGATAAATCCT
+
(&&&%+)*)'("!$#&(!'%(+!!##+($"**#$!+'$+)%!"#&))"%)&'+)!*(#$!*%+#!*&"$(%*!*$%(&()'%!)%'!""!'%)"#!#'#+"%()&%"#(%"+!&)%$+)&')())$$)$#+'(#%*$!)%('$*&&#!##$(*'*((("")##&)'$"+&'++*%#)(&!+$')(#$$$$")"%+'*)$$"*%($('%%)("%)$"'"')(()*%'*+$$'("(')!)('!!*"+%!%)"""#&!'+*$)(+*$%
@r8052
CGTNTCCCGCTCAAAGTCCATGCCATCAAACTGCTGGGTTTCATTGATGATGCGGG
+
"()!%(#%)&+$!%(*%'%"$'*%%"(%")+$&$((''(#++#'!!)#+#++*')*
@r8053
CACCTGGCTCAACANCCTGCTCAGGGTCAACGAGAATTAACATTC
+
;&EG!#@0=-&3<E(*B5(%C9@C?GH"&<1G7C3=A.(!EEF<E
@r8054
ATAACACCATGAAAAAAATGCTACTCGCTANTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCC
+
54D!;?;%814EBA<?+6*G/$+4+(6/#E9C4B7$4'1*A5AH&,+)++$>D4=5')01G4G4A7;$.$0101)."7=);+4)G!D62$?##-;-541)#3A:$!37.FB(1-2H"+GH,.<
@r8055
CTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGNCGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCTAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGA
+
.&"":+&7@(AB6>#)"<)#429%@#@(4)2#G@*%*5G3:**%9&"-9C-907,*E;*B&@C45%;"2"6E:!$2C6(:>9;#;)?,06-5!)34>!8B#A*</>B;*"@BFF)03<='>1FC,?="1"CH:G#-7CB'#"7,F6?8D#,.EH4H((.?6BF=C#,,1?(9GHC9.11F(-#E?<)/<EF'!"(&,,(<80+(<)1":-#4:
@r8056
CCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCNCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCA
+
>D5@137#3@#4)$)25(D5=1/#F?;9C'3F3HHC;*%C<:G"()711(+*;0B'<G@87=)+'H$&AC$@13!7*(-E9<8%"+C<E9<HA,=3>1;/?DA,13'>+)A<D)D(FB5&GE8>>G@G:
@r8057
CGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAG
+
$BA?CD>?$"/D5,22/B/6!)3-?AH<)+7'B12"F#@?&3&&F#H?!!H@-+7A(4,$*:6(0:?:DD=8)E/3D++@FD14H6+'@(,BH$0F"60*E-0!1$"#;"A<,@9<G1::7BB),$1/0*1.)B&BGE7H/4=/:4FD9>"29:#2)96DE*=?-$#A12%E?+1;+/9+7A+*G3
@r8058
AACACGTCACAACGNCTCACATTATATTTACTATCTANCCACAGATAA
+
+)#"*"'+*&%$))+)$%("#!'%*()!#"%*#&$"%##$&!)*#+$$
@r8059
ACCNTTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGT
+
%'("$+)*"!%"%#(#$$$+!&&%+(")!%+(#*!'''&+'(%+('$("!!"+!"#+!&&%%%#"#)&+*#(+#&!#!
@r8060
AGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTT
+
;FAH@'9,#=%!7B?D4;--%:A:<&A<"=?+#?D26D89
@r8061
CGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGNTTT
+
60"+4A<"?8*C5.9)44G/G'2B/)6;,95%GCG!,*:A/2#="?.G265+6%@GA@>.'B%?>'E>,0.:0;B9A*70H&?"$.@);>0A62(/75A%%B->59-17.A=9CA:G(9B:75/FCF?1./DCH@.9*.27?&G@<8G*%///7%>#B:2<54H<!G!:%!?0->%H45AG(%9H<;
@r8062
AGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTNTTGAAATC
+
#,6?,D+C-GF3H%16!?A-7=>1E'!)995+('/8?2G<8(%
@r8063
CGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGNCATCC
+
5=?%"<<,!@4FG<8@#.56!5$+/.D7-2A4E-.HA0#='7&
@r8064
GCTACTCNACGGCACGGGCCNGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCG
+
+#?1%4/@B3#@134;109H5=H=*%<-(CB<4%-(9FC>//'0'#&,(1D'+/9&H>0.)2+*8*
@r8065
TGCCNGAGCGGTTGTACAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAA
+
:8#?$#&''+A%1@F("9"&8-"D=?*F5#/'='&92967&%&43DA*H'&:97+*4+)A:9$>
@r8066
NNNTNNNNGACCNANGNNNTTCNTNGANGCNGAACTNNNNAATNNGANNNGATNTNNCNCNTAANNACNNNNCTNCCNCNNNN
+
"$""""!""!"$#$!""""$"!!$#$$$$!"##"####!"""!#!""#$$###$###$!""#$"$"!"!#"$##!"$!#!!"#
@r8067
GTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCC
+
*#(#+'''($)#'%()+('&&+%&$$('!%)+!&"'"!+'&)$+$*%!((%(#)%(!*'+#&
@r8068
CGCTACCAGCTTCTTTCCCGTTGTTGGGATGCCTACCGCAAGCAGCTCGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCNT
+
(24&%5'/A*=4%F(FH1>E"9+?.>GF+@;H!*9??@6AAB5A@85""H6%2A@>260#"CAG;F(-$=-C!G6:D%1'&3(4%'!@$H7*A?+E>(C4/?8+F&2!A386++(!*49<48$H-!=H07"FF245:8+E.+F&B.%
@r8069
NGNGATGCGACGAATTTTCGCCGCCCGATAAAGTACGCCCACGACTCGTTCGCAG
+
!#%?H%).$69024!=/+D%?3778#@5C..C)(A$,#5/:$>+E62A@0)82.@
@r8070
TCCTCAAGTACGCCNCNANCNCCCGCGTCCGGCTGACCAGCGTGCCG
+
%'('$$"(*&(()*&(#***#++)(((!(!*('"$("!*"!$"+!'&
@r8071
AAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACG
+
>!F6G868*;+/.&5*6DG('H9=9D;.3@=)>=#,(9G,',9(83B'3>2GE;.F?,-"@4.3&"':%E5D;:,+8'
@r8072
CGTNGCTGGCTGCNTTCGGCCAGAGCACATCCNCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCNTGGNGCTGGTCTNGTCAGCAGCAACCGCAAG
+
$(&#)$)&'("&&)$%(()+*#'+!)$$%'!&$)%*)!!'+'%"!*+$!#'%*"(#%($'*!$%)*+&(***"')%$$!(*$)($#"'##""$"!)'))!
@r8073
GNNGCCTNTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCANCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCNACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGGAACCG
+
)%!%#%)(+%"*"%!("+"%"*"#+)*!))$%"*+*&+"&""'&#'#!)#!"#+)*++$"!+&$&*'#+((&(&!(+#%#'$$)##"%+($!%*"&*+*%'%"'+'*$%*!(!!')#'%%"%!%''%+(($'#*%'%!(++%"(###)++!##+(
@r8074
TCGCNACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGNAAAAATGCCTGGTA
+
#&#*+"("&(%(+!'!(#(#$$'%#&#++'%"!'$+&*)('$$$*!&'###'($&%#$#)&"$#'#""$')+*'#'"%)")+&"$%'"(&")"*#$($*%+)*')))#+!)%*($'&"()+#+"%*))#'&()#"')&&+$&%'$#)(!(&#%+%"+)#+#*$%''#'(&#((**)$''!&+)()&*+(+)#
@r8075
TGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTC
+
,F.G$'5GBED;>4#'--&D3/#/&%&<217=4$8+7+93&!(;<%2,
@r8076
TTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCG
+
4B/#G#2*'H;%44A<&9>!"=G1=>&C0?*2"8)3#D)5(9+5A*7)B*(F=/!;9=%
@r8077
AGCGCCCTTCCTGGTATGCGGATTCTNTCGGGAGATAGTAATTAGCAT
+
:*(B@0$:D,,.>.:D=%5=$&/5%#9B%0"3.3#G>)A<;1$?&D9-
@r8078
CTAACNGCTTATACAGCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCAGACTTCAAGGCT
+
&#'%%%##+*+'!"((!!$)#+!%!)('!("$%*(#(&%%(#)$!*%)!$+!"&)$")$'&"!'#
@r8079
CGTTACAAAGCGAGGCTGGNTATTCCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCATAGCCTTGCTCAAATTGG
+
?3C6D89$=+;H=@%H'5.F)F?-8+;4;D,F/85/5-&E:2.;G>C):D?5D"4BB(&,C:B8#/3+0C3-.F7>,@(,,E*(G<$B3+B'8#9,9/D/$14C&F>/E#%/C.5#A)+734GF=!.$F?3.%:<)51)@C6,GB7"B<B+!09GH%0$-
@r8080
TATNANTNCCGNNNGCGCAACATGNNATGCTTATAGCAATTTCAAGCGACTTAAATGCAT
+
)*%#)"#!!"#!)$'%*#%**)(&)&")((+%!$!#*$$&+!!+**"++$&)+)#*!$+$
@r8081
GGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGNATACGCCCGCGCAGATGATAATTACGGCTCANCTGCTGGCTGCCGAACTGCT
+
#,#+*G9>9&7A?('H@5>F:-)"F0C/E/BD*91D!404*=$6<2/E17EB?8A!'4*0H2($0H)&1</#/,C,E.12,A.C#+(>'1-H>-!>D$?7430!/,9D.&.97$-;%1,@<6>.7,H+&-729'>DA2:/CD-:BF
@r8082
ATTGAGATGCCGGACTTTCATCGTGNGGATGACTNGTGGCGTAACGGCCANAATCTCTATCTGGATAATCTGGAG
+
(0EA$)81@E/A?2F86::<))?4"-@E'$60?)#''!,F5*G9EC;-B4!*1#(2"C@;:6(4!,.*4HF#>D&
@r8083
ACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCC
+
C2?G:7B4D%E79>A7C5!<F@+>G&0?%ABH3#1;%51>7+?58:2&91$E-8;%&(6-*<823-
@r8084
GATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGG
+
H?F>1B2@'*F#0A1.(H$<@?.<18G:66.#203A159&,229E/>7,.1/=95<@17'2=G22D%A(=)&)>H"%=AE6"%&/$?F?3)E/6.!%32511
@r8085
CTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGNCTGTTCCGGGTGATCCCCATTAAAGGGGCAT
+
1/,(F=-D,?6>6F/>/,0(B@B1E>?2*7)1+?AF3.B,A<41(E5=01B/$(,(2$:E7?A$("*8$",,+5=@4G!%$
@r8086
TACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAA
+
H$>:>402?&!$4D35($C='"#+.=&)@.?1%/<CC8,,-4-$9".D)'%3+%9
@r8087
CTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTNTG
+
E"2*#!64!(H+89+"%D=5!E&,G102&C5%&2A=?D*,G3(>1;8#-A//B,*F!B&$C#G4;&2*+756?C.27>C)09#,D'C-6,2$%C?3-8*##G<<$F7<83AE83>
@r8088
TCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAANGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGNTC
+
3?28%A".+896+G3>@?/'179(G,599&>;F3"-:,6>51$F!.#"D-;-<"E@G>C'(''63@)9("+.!&ED!%#9*D6E2,2/;5=2A;A.;>*/H
@r8089
AGAAGGGCTTCGCCATGTACCGGGCGATGTTANTGAAATCTGCGATGATGACTATGCTGGTATCAGCNCCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAAT
+
5.''D6A5F5G&BAG/E+=7)CA9@"!+!D"??72/@17B<.BBB6!"G&>@@5(6!7:8E-=4+>(;>17"AF*75F$)/?2-":319;C?@.CF7<-4F>#2(2$;?(D"?3+H@)*&.4?)3DFF+
@r8090
CTNTACNCATCCCTTACCAGACGCAGGGCAACAGTGACCCGGCTCATACCGCAANCGCGCCCGGCGGANTGAGTGCGAAAGCGTCTGCAATGACCCCGCTGATGC
+
(&"'"$#+*)&*"%$"%'((!$#("'%+*'++'$!$"+*$$+%+%*+!'"%"'*%(+*!&$&!!("$$&*$'("'*!*'''$+"#+*)+&"&'*&+#'*+)(*#+
@r8091
AGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCANTGCCTGGGGGAACTGCGACTGGATAGGCT
+
12DFH@E"0>4GGF:D:#;G9D*3BG>BD",?55A)6*GC:.E@+-;'@-#?=;33*/A,,78&1*!*6G32*>:=D58>1"./>5E3F7<H/746#%F9/3B(-.BF&-:*"&:.$G8#*$9#8HCF:
@r8092
GGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACC
+
F(>2D-99AA=94<'7?9D!.>'D(:6.="C6.*@80;G'4(<;*/8D0AC?/AF?,*2%D15)&%.-AG
@r8093
GTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCA
+
)4,3(@66'1)).7*17CH>1FC&?)>A3,26!;%1-=F1$(@';-$#6>(3*&F%;CE#@F.43,3A(*E2$+&7>:H21&9E<9?3B+1+93*8@707F-16<*)%;)D!0.9H//=8",!9C--5&7(=(E'+8'"(.#)(8=CG$@4/EH;/*D78C8;/@-,7%4%%2<0!30C3.4D
@r8094
TGCGGCGACGGCNAGCTGCTCCACCATATTCCTGAACAACTGAGCAAA
+
E1F8+2*(4)%2",=,>G/-C1B!-#**#$!'14)G'8:7(#9*->C+
@r8095
AGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCANAATCCAGAATCACTG
+
/<<(A1A<3?+4%)A=A.";!'-D=$"E=&,<+E8%A6:#48;9'0!"08AF/&'5$E6;+)GG<,21H:C0'7F.!0..E/>8:$CHB(+AEF;0CC+-93)
@r8096
TTNCCGTAGCGCGGCTGGGTCAGCATATCCCACAGACACCAGGCCATGTTG
+
!*%G$A>#<F.)50=1(<5BG+"//;)&.?H-A$+"948>.C22C*D=."0
@r8097
GCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCNATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGAT
+
:044.@C'G40:,/,!4D>EH*7))G)&<+1,H@!FE#"1;-2:C4)@'C)C:BH&-"*&;.,0)*:">-$D22;D8F?2@8?;=GFB?7;9@"/5>+1E9;E0>%FE9&98B1@D<#'=!.)&'GB3>H,63.F3B3"$/%A"B*E-"!)HC31>404C&G),=>*"$>0/1",?'E5,H#,;.G?
@r8098
GGNACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAA
+
*)%+&'*+#*$+'%+(&)(%%+'#)"&&+(*'&"(!!!%((%*'$!**
@r8099
CTTCCTTCGCCCTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCGCGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTNGCAGTCCAGTCTGCATCTTGATGCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGG
+
*G%GACD+29,+>*)5$@#"?B2H%$H'#%2EBA70>6C;H*&ECD@7>",:55((4('&C==4#<(&0&#658/#:;#3F%::0A#6"950@97)!#;"2E::1"%@4;F>;>,.56&#.@@+B$!F<G87AA$@/2(+&B&C2>&;A0@'*!,89"9'#.6D+6+=;8)(;,6!&!66@8G,&68!4=F/%.F4>!4>%B.-8?C$H&G*('8!-56;5.572@*/+6-G*F4($$E(,9)32(*/-CC7759D@+A#--)4?72,>'0
@r8100
TTGATTAGAAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATG
+
&+$##'"*&$+$$)%%+(&)#$'**"))*#(*#)#+($"&#+!+%'$+"(*)*%&!(&"(&$#!%*!+'$'$"$+&(('!$"("!!"%
@r8101
AAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAGCATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGG
+
.=0;"-.8?47D66""@9($<C&8:2;"$$-2A0D05316&=HF88E;A7!)G=?!8H:.=>C5%%*#A5H55!>B-E,:%.72*3#F/8:A66:.,A0("6!DC<F=1H?),'*D22<?AAE@3?GG=-$<)*46$&
@r8102
TGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCT
+
<C=/124%BCA#G.8;GEF1(*;'(;($+C.7/9"<69<)B@&(1>.9B":,==(9+;:EH65'.C5&!+=G0!0C@;6/
@r8103
AGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGG
+
+!)&(#+"#%'!()(#+"#!%+'!!&($**!++!*)"&$*%""#"'
@r8104
GGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCNTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGTATCGCCCTGCTGCCCCCACGCATTTACCGCC
+
H,2<"-@318,A+3?!E3'GA'FHH!C&996'FH"8;$3(9=8(57H)F?#3+:4'C&G9>5?<'=H897=:!('6GF:?-C"#??:%6GBH4'+0'<:DH,12832D7>1,1A)/H1A)H%3E#0G8FC
@r8105
ANTGATTGAGCAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGNTCATTGAAGCCTGCCGTCGGAG
+
5.4@D1@?+.:!FE)A0D'1-163H'G)E>@B+1D."D+G-93D&;@6-(>"G'A;$3CD-G?%$*-8H@C<G4@<5"52>-/)
@r8106
GAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGTATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGA
+
G5:71-)-8><9A/CA9@4)E!=!95<2:('<;;%5E,-!%:H0>,6E3>(!&BA:B=/>#BF6FH9(G;*2:B!80"/6+2C!:;<-194%/E.(#<<$C234/,23.0;??+(";65>07)>!9C&0;"EA5E-'4"E%-=9B1H&?=A)4+"E7G"/"'HFC0.":'$E8>8F'%DBE+=<,6<>++4(2F(?1/1)6D*HG2@!()1HA4<<!0HGC&G*$H*?+A8+G('H58
@r8107
ACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCANATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAG
+
'3?(9H>"=37;+007"@=#&6-H#G1$,:'*&5A&GE%2H%&:58FA=@@@4AHB>0>"9HA1'0<"E%H;'?01#E/&<(9>'A/?0>1@1)7H(E71H3'!7E3(0'E+CG(7%:E9+"/9;<<>((&.!348)0@61677#5,F;+;)-G+GC431(%"1@C=;,28E.%)>$)?*!H?B1.>EB)*99E>C)##1D?*"B+3G+B%;B"A,&")5"$.(FC+3F%%.#):<(4*D.BA70@FDF,
@r8108
NCATAGCCTTGCTCAAATTGGAATGAGGTTTGTGCCAATACC
+
$59#C$3:<%%?&:-,/<</%G*-,-E9*"5A+%!.G&?>=:
@r8109
CAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGTCTCTAGGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGACCTGA
+
..%$'E6>3<5&:$#-@75(-)G?B5$H8(HH#<1652,H6C#%C3H<,>1*G>2$AH*!6F57/'%/E.8F49G2H8':5<=/:2/?,/=9);@33E7@H)776@!=
@r8110
CATAGGCCGTAAGTGCGATTCCGGNNTAGCTGCCAATGTNCCAATNGCGGGGGGTTTTCGTTC
+
5A1G+H&)7>!@<@<"5F;0@=9H:$5G((</B"H9+"?B!?3$E5-H2#;564$$+3(5$%(
@r8111
ATTCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTNGAGTGGAAAGCGAAATGGGGAGAGAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGACNAATGGAGCAAAAGCGACGGGNAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTT
+
(#!#%'*+!*#*!)%##+(#)+!%'(&%+'(++('#*)!+'(+"&#&&"+*#$&((%)&(+#$)%&*+*&!"$#(*+$"%%#+%%('"+*"&#+((!&+!!%#!(*)#**"%$%""*%"('"+$$*"&&$##+)$##'#$+%!++'"(*+'*(*&$+*(#"'''$#%%&%%)#(!$&+#($#(!(($'&&#$"!('!!$&+)%&!*"*!*'#&+$!"()*%+$$))#$'%)"#!'#&(*)&**!&)!%&'"#*)##($+)'(+&(%$"(*
@r8112
TCAGACGNTCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCNGTGG
+
,6EC$+,><3,-9);1?A9*BD)G;<<#7$.?A,"4@G,;=@ABE5
@r8113
CAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCANTTGGCGACAAGGTTACGTATCAGGAGCGCATGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAA
+
1E(!28>*C)&9752/&-(-6$?%$&EE:)2*%3;DFH:4D5'4*0=%789!C?<E2BG9%D9(?<()861(-6D*E8!001790"B",=D($><<H!#72#%3,//$<2G@73$?/928G'B<90<F),>CA=!F@*2*>?1;&-3)?)?'!':B:1+F?B";*B<E7E:,<&)-$#;/GH.*$@)2)/3=4'#2588=-6*/7"+!8>>"3;A(<H"?1D-<EE%2</)DE&--=A9+--9D,!<*
@r8114
TTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTNTTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCC
+
H%,<@D0$*/)4=)D:E,AF.1>-?5-"<8D1E,B:4-4"/E(1"9E7A'C=/2/=+,-F26A1:"1=FE->@*2#(-0&!2F@(7.B*9;A4'A?1(E)+C:'H1(74=#(@<<%:15&.7A41>C+6F=4-C&;*AA';<$5%%1%$B''*09A)=E6&%D3&315#;+><:+013BF
@r8115
CANGTCNTATGAANCATGAGCGGAACGGAGCGCCTCNGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTC
+
&&"*'&$$*(&(#"*!&'(+'"!(++#)%(&))(++!+*&&&)+'**!")(%&)*(("%&"#*$)(#$*#&$+**)!+
@r8116
CNCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATANCACCGGCCCCAATGGCTGCCCCCCATGCTGC
+
%#+'*%*'%$!%$+))'#$#"*'(!*'"+%!%$'$*$'*&'#&))#)++)+%*%%''"&'%(("+!'!*#$**)''$"#'"(*(""#
@r8117
CCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTC
+
%;!#'3*HF'FA.7G:>6''<9.2C0F28:(F19>G6#38C-38?.,81.0)#67?-6("<.-H/@DEF.74&6)A>@8*CBA>5065"/5F))-5?C2.'/!4,*8H.!.*7"2<8
@r8118
TGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCG
+
4=:9960.3.=HA->>%&C/0E*2/E2&42-$7F0=%.?'H(8A.HD2F'B154FG/*!=+873@6?-!H)!%E@7"
@r8119
NGTTGCCCNCCANATAGTNCNAANNACTCAGAACAAGAGCCGGTATCGA
+
#*"*%)()"&'*'&#&$&"(&!*!+!$+$+%'($%#*'#*%#'+!%!%'
@r8120
CATTTNTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGGATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGTGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGC
+
60$%3/1%8D"'"+=BF=;#9"D813%E83F;%G>7;>*@34-/G#9>8D:E/!2D)=.:6+1:,528A1;<!;&34/A=:7,*>H2(31<45D.'B-@3&3-G7&6)A"A17&*1D<H=B!!,(G'F>!DE0A'6949<+8D:H;
@r8121
GAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGANGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCG
+
*7;?3")>====?CDG)9-ACB+4(?;-#B-B5,9!::+)$9/!74GB?C'0;8E<=3.?!&CD&/B'HG8@5-2&E#"'(H)&B-F!4;2.A%"165CH%G'D-+0;,+=5=:0,%?
@r8122
NCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCA
+
.+@?>3G*##0D.?(51(%E2%,=4E<""H<20EG:!=/1E5F!'A95G54HE**FH4#
@r8123
TAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGAT
+
02<&BA53/CCDD-G<5+E6D94"0(;(C),#91&0-H4194&+:0
@r8124
TNCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGNTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTA
+
%#+(!#++%*$)(!)'$%+###&##)%'*)#'%("'""(('&+#('#$%"*%!""'!)))(')##'*#)')"(+#&&()$#$"$)*+
@r8125
CTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTG
+
-0&/?$'"2C"<(A3F%A(@1"+!.510G0(B'#F+-F-9*@'D&F:8@%6$%-#F255F.#2!@2;"7+C.;E%"-)GA82,FAH8#5@3E?2>"=D?E/#5?9F-(
@r8126
TAAGGGCATAGACAATAACGACCGATGTCATATACCCATACTCTCT
+
8"()9D!0>8/=(CE3B&EH?E@/1:D;07!!:/*A%+>)*9!(9;
@r8127
GATAGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACNCCCACCACCGGAACGATGCCATTC
+
(3#07F>B*-+;8+F08CF/<70+=)H'2'$.19"6>C#1E'GE!.6:%>(%"!4/CH*0'G%:15DAE&8-:$?>'#:/4-.0$,9H@@83>;7
@r8128
ATATNGGTACTGTTTGCAGGCAGACCGGNATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATCATAA
+
;993B(.03;H7/0#H!%-7E",(D%*>.6@GE3:211G6$">H/0->,7A?(2"7--A27<5;$365:4*-9H>$,&4H8,.,E6C='G$C4
@r8129
CTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGTCTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCGACCACCAGGGAA
+
36+A),'?<>''(A)8;1//@7G03$B6'67?5.&/*56D('F@10$(47>!BC,+%<)0@:(8=4/%+>3!:;;*8"3#&A"$F:/>@3D)<BD0>2%3;''?>*2,(B0?HF6%9=E478:G3%<$##A#&42##G750C"!5G:$)8':0;H8E)1;/=!<3>7/)#+
@r8130
CAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAA
+
+4'*B$:5G+C-)=;8)3GF4$6=H;;F&=<7;<)BG#"4844G)G&5?@#!!#.:96"D0305,(?!1#*B+G)$F82
@r8131
CCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGATGAGGGATTGCAGCGTGTTTTTAATGNGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCNCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACG
+
."AFC:6-!!(992<;#&!DA(12/>&4H;'9H<D)&E;+E'H1&6?9*:$<;.05D0B<&1G+?+)--CH9-6'8"*<A<36=>4@/#)AD2$/4(G5/3@')7>8(=/56:,52!E?6D1<.4:)5E%C5.$E#)@)?=EG+%.0A785.8&#H<8!@05:1&?6AC?>6BF%C+>=51&/:0#<:)6AGH:2C9@1"!G6"8B3#:H%)C2?E-;!3#-(.=F,8H+C2&>B66/-9%FH8&F)4@6.'!E.0'#?>H:$;=!"
@r8132
GACATCATATGCAGATACTCACNTGCATCCTGAACCCAGTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTCCCAGGATGGCGAACAACAAGAAACTGGTTNCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAA
+
F#'9&)D+ED+$A5FC3EG%,A0&"?C&??0,$GD/EC(7+#;$1&,'H/<AD:B"5<3"!21(E+#65#((B'11/B)3HDD*0"H*+;.4,9(E#91/<B!1-#<A(.4GA+8G-#/?AD,93(?=!%0(4562A'380>C"9-)C:'48+"*G>:<8-@@#-?:7AH!!-A.A0E.;D&;B/4.!'(6.&*@F+;.C4**.H':%C38@,'EG*,!8/%H6H!=;
@r8133
GCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCNGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATG
+
E/#0@B0;"'DB-<.0G88&647E-7@#BCB:.1B1<6-%.BE"61CD!)D3*51.(-E+<#<@>;*2H+,F1$+)F3;6!1",=D!
@r8134
TCTCTTTTAAGTTACTCTCTATTANATACGTTTTCCATCTAAAAATNAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATA
+
441(:3&"DA5(#/E-8&@,A?)#F0@@/H/2C*)=D#F3:B?(#.61?&."!C2)5(GDG7B,E%C9*%+F.CA%#,C)4/3'+%C!E%%
@r8135
GTTGTTCTTTCTGCAAAAAAGTGGGGAAGTCAGTAATGAAATTANTTCTANCATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTN
+
E*EB%5;)*6H62-A!'"$*$%A<--((0=%=4&*0+@E+;&@04:=*F*:CA@F).>56,2)<</H":A#?B502#>26=H/,9F<A78-87#A7=%<#-B,(2
@r8136
TAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTT
+
A):>2>!C'@(?1@:;>")E=7BH):,!?#-=<ED#G:+#C:/B*5@&G=BBF9>$5,'@%1G3CE
@r8137
ACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGNTGGGCTAACGATATCC
+
3*E%,?,9%3F2/%=<97&$243.0#?$F01;59*2A$."??F2(GC3,2@12(D(;:H#91;.5D3.)(,/-6A*-H3<?!HGG=-@1#@#F
@r8138
GCCTGCTTAGGTGACGTGTCTCGTCAGGTTGAATGGCATGTTCGCTGGCT
+
''#,1'#9BD"%E4EE%9G49#6'!F&/>C"/#%7.)2'0.70HA1=284
@r8139
AGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGNTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAT
+
7".7G"%?G=(B2)D%%*1,,D,1<:F//'+&F*785=0H@7+G?)D5>;1?!?'B9!/%FC30#C2#/),@9(C&268H01:D7?1A2(%#75@GBHA9D>@'+:C)$;?A-A3&"/&D4=C20<+%A&-
@r8140
NCCTCGTNCTCATTGGNNGGTCCNTTGANGTAGCTCATCTGG
+
"$$'$"%%"#$(!)''*!$**&(#$(#"+%+*$!'"()%$!$
@r8141
TATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGANCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGCAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGC
+
2EG3#9=B#-0"G>,;#,::#&77AB;,>G<!&4/(C'0=3$)BE?,5>/?=C#>*?C*H)AGCAG+'G=A>?"$.11C!74/A-B'=23C9*@5?-/!/%H150>*&?F-6H7=(6'D3H2259F>.<"C,(.3$!3A)+5%A:26A46%,<3=:=%4,6A!C3'(/,%&5EC=()?G8,8!.!CD@;&-A+)A>78;/ECA2';2E5H81><@449/E0'=&$?A40?H7"<$B;-74*CE%G6#E.DG31.2/D.:!=/%"(-*"D1/@&!@G"%0<.*
@r8142
GNNGTNNTNNNTTTNNAGGCNNNNNNNTNNACGTNTGTNGNCNNGACTANAANAGNNATGGGGNAGGACNNCGTGTGTTNNNGTNNNANNTCNAGTCCNGNNTGCNNACGCNCGNNTGTNNTNTNNNNCTGNNGNNCTCNGNTAGNACNGNNANAANNGATACNTANGNNGNNGGNTNTNCNGNNNNNGNGGAN
+
"!""$!"!#$##!$#!$#$###"!"!!#$!$!"$!$$"$!"!"$$$$$#$"$!"##"!!!#!!!$"$!#!$!$$"$$!#!##!#"!!$##$$!"!$$$!#"#"$$!$###"!$###$#$!!#!#$$!""$$$#!##$"$!#!""#"!$#"##$!$#$!#$$$!!$#$$""$!"$##$"#"#!$#"#"$#!$"$!
@r8143
GGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGAT
+
>'.#5#4.&+<*6?3AF6B>)?>+-;4#?(,-://#&/7%><#A;8@$HA8<-@>)@-*@;)-<&G7@BF,%E96*0F!/17:/B+H""'F>$64B@8(?4F9='0BE+?<>'<&=70,+;#&:G27@@#ACA68BF6FFG67(64!,'-@6"5BF?D$4
@r8144
GCAANCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGG
+
27D=<=7&A*!8$H7*D535""2C=-?'@6<"*&)+GA,"!
@r8145
ACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAA
+
"5/HD4%F)81?5C/@/B*E13>>9G>.%9?#HFH8GC%=(H#A<+AH?&+
@r8146
TCATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACNTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCAACGATCGCCCGCAGACACCTTCACGCTGG
+
53$$@-HB4H2>+9-DC8/G*(@G/H&=C**&D*2:7"G8/$2@5G@(?7+>(=>B>-%EH:->620/G/)8<42/F1>)$11#H*/GH5#HH@))=-'D$9A==56>G%9G'86AE987:3H01AG).29*47,<)'C9/<>7$5=3AD-?9E<+:E.$5=!01)86DB-1/@9!H(;8BB./'HC&29E3@?2@&6H@A=:9$6,@E2@+4G96>78=CB;C90'>!:&AE
@r8147
ACGGCCAATGCTTCNTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGC
+
F0!>)>3D-#C4)6/1D0>77*%'F(&577"A#HD,&83'5C%(F)587A+8?-
@r8148
TCGAACTGACCATAACCAGCGCCCGGNAGTGAAGCCCAGATATTGCTGCAACGGNCGATTGCCTGACGGATATCACCACGATCAATCATAG
+
*)'+&*))(!#))%'%'%"#'%!(&'(+"&***!*($+&"&"$*$"()$%+*&(+)+''!!%#")("+*'"&)"$+"!)!)*!%+%+#)$#
@r8149
GTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATC
+
=A*#7ECD7,1:79F&,4.7$7*'/-:#+B#C3#.20-1".FEE'7=7#?%0
@r8150
ACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAANATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCA
+
)$+$*()((!""!!'!%%+(!'(&*#'*('($%!"!(%#&+"")*+#+!&(&(!)!%#(!&#"#'"&%)$&+)*!)()&+'+(%""!"#+()&%&$%&"+&")&
@r8151
TAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGCGTTAACTTCCGCTCCTCGCTCATAACAGACATTCGCTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGG
+
9=C+'".''+/53H28>+AC;/$>'?2E35/9.+B:=%:;%<%B1#%%#%H%659%*$/98632F%$.$H/#.:D)A/@<+&#+74=7:;@;AE',+C';5G7C6B@.<B$"8E2A*A040;A7'&;C'@9'"%&/#8CH(%&-%&&H-B$1A>)06$';@:$/.=@7E<;)@)*+<D+-CADBH)8?$$/..A
@r8152
GCAAAAATANTCAACNTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCG
+
@'B!=G5=01#,#4&28A-!*D@""@-;)!:B+:7>E-H6HDDE*DH"5,=)E!;*/@=+/?"G
@r8153
TAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTT
+
>+G;.F4A2%#7;>&<DA1:+742,0=51+;,!)H-D47(/$8+F@!.!-%>*E&*"2.5?H:)#9/%+/3DA.0$&8H>,'B-!%D#07>%'91F33(>>=)-FEB6C&#F8+6G*E<6A6=.E;F6(.;=H4.&A.?G.<@A%:B$D,!"45=7D9++$9F8.'D>(2ADB/35!-%:),C8A+)2A##.FA!&%:>B71H"?-'$1B/
@r8154
TTNNANATGGTAGAANTCAATAATCANCGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAA
+
'!!('!+'"'*#(#*#("+!)'+%!"*+!%$%++'%#$"*$&"'!+)*&%%"($+'##%%&++&(%&(#+&)))("$#(!#)!&')*(!#"!&$
@r8155
NNCTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGA
+
#!A8E(BAB!D,BA<1,7E"H(%)-@B:$$<6&'$D/!5A37-:85&86.+*)<D508*!(.4-H#.4
@r8156
CATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCC
+
:2(F?&B612HE.5FH)E!#*,),<>B9.1@%$<1DH8,;BF4+B99)B>3)3#B1-=9H;B1AD=/65)A'G*%
@r8157
GCTCNGACAGCTGCATAACGCCAAAAAATATATTTATTTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAANGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCANGC
+
'*$('#(+!'+!('($''$%$*$'*(+&%*!%$''*$'##&"%!!#!'(%$!''+&+)))*""$!(()()&(("!**"#%*'+#(%)($'+'+#!!)"+"*&+'"+%!#"+(""%")+!"+)*#"'))*&("&+*"($%%"+$$!'&''+
@r8158
CTTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCAGACTTCAACGCTAACTTTGAGAATNTTTGCAAGCAA
+
(@-DE)$H7@'38$>13#+6+!:(9)/*A2*36#,2*="2EG+1$7!>(!?HA&:!G,(E4B*"#'>.B*<#FG)48GDH8%
@r8159
CGAANTGGANNTATGNNGATGNGTCCATCGTCGTGTNTTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGTTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGC
+
$%*&!"&&'!"$&#%#!#'*$"#!**(+"(+%"+#&!'""#(#'+(&!+*%'($+#&!("'+)("$*+!!)*'+$)((()#)!&#+(%)+))*'"+&%#)$*'#'!%!&$+'&+$&('**%+#(#&(+$"#%%++*+!!(*$!#'%'+'')
@r8160
TCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATT
+
EC77$9?1>B716E2B$)'#0;/B(6:@<:A!D6>-31G,;,C?.$%7,?0C'3G=A$B"'&5>F#$-H8*G"1=)500.(,9%&2.G<A=+C
@r8161
GTTATGTGTTTTGGGGGCGATCGTGAGGCAANCAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGG
+
&(+'&$%#$#)&#%"!)%"')%''#$#"'"$$%%)$$+%(!(($)$(%$#(($(%$)+*#*&)%*$)"#!')
@r8162
GGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGT
+
B=GGD23#3$3.D,+'A'@AB8$D.<C:%'70*;0AA7,>
@r8163
GCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAANTTTTTCCATCGATTTTATGAATANACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTT
+
A7751+)0B!6!0%9A@F54EF@4FD+1)7:?*.:A.(D73/#A*>*E)/5/>485D9DA@,E=<G,"<9;'>07(13.,7#?/:C3&GD@H."$D<")*2!12)BEF5D<8&)=(!A5E%9);#,,,>*(<3A$<1A>>2D86>3C):,A;@!%==DH=!/(&')!+9,?D#"GG<2;=8<0$%G=%B4
@r8164
ATAAGTTCCGCTGTGTGCCNCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACNGTTNCGGGATGCTTAT
+
*E5H>$"'2=&0)G=%B3.3'D=?.4;B-:&D@&0,:5(?%;<;,@(-2.FC.C"#=AB,%5%@&%#.6"&5-8F>90)D</*FB3
@r8165
TACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATC
+
/+A5&A852!36.4-CF1@HF$4/.*17E(:5D+39:E>H!#"<2D!8B4'@B@=0H=AD9B,#%?8'@@4+E<>+,)
@r8166
AGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCA
+
=999B$/,9CE7C&%>*4&,2&0@&,"9:G',F5#58/,7&6;(*A#0AD(3.-D>:;7%>ABF=&8+#-+2!<,/GA$#A(,'04*E+=29!+;*E4>;EG>G<?&#!$0B2E0E8,C9&)?<&9?!0
@r8167
CGATTGGATTCGACAACAAAAAAGACCNGCTTATCTCGGTGGGCGATTTGGT
+
CFFC-@?0>8GF-E:;A:#3@71"G#28$"D!A;7/=(0&E(1194)&E7"'
@r8168
CCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGNACATGCGTGNCGAAGAGCNGGCC
+
&&+""(()"!&#!$$("!%&$%%!(&%')!%!!$"$*"+#+&(*$$$)*"(#+)))#!$"!#+$"*$+)*!$(#+!#")"!!'*""$#%(%($%""$$%##!($#(&#'&%*!&'$&!&$"%+%"#&#!'!+$%'""#%!"!&"*+!(!)+'(()&&#&%*$)*+%$"!&##"$)%("*)%+&+#"'#''!
@r8169
GTANCGNCGTGTACGAGAGGANNAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGANAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAG
+
"*)%!'*$!(*'('$&'()!'#+#+'&'%*&*+&&*#)!&(+(!!)#()+($#%!)&")*$#)((!++!'"''*%'"*&$%(++'%#!$###+)!*'+&*&&$)#(+*'&'%+'($&%+&+'#&+%&!)&)#!((%++'*)*&&*)*)")!$
@r8170
TTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGC
+
<(?'"08/3G4D*!=63FH88.:(".2G*22)/(-"&H-$E?$'<..4:,8;F8
@r8171
CACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCANACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTA
+
1G=2"0D1?HB%);:262H7$H)393C9%%?:H<+#24+&F=04B9H4":2.:'14;#?&.2&40@D??5/123>$.4$('(3$&51H8@)@-;!#/!,+$@+5>C<<.9(1@>#%%+('=%2@
@r8172
TGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATG
+
3/G)4$B#0@2A*3#&"+%6"9&&(#)"3?22=F,GC?822%F=E?0C%D9G)A;#.&$(<0"@?):3*$2057>A3+C+18-7#
@r8173
TAGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGNAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGT
+
GGBF13-G!!=$"#&E0?D0@&#2.B,.9<6&=GG3;>*?78;7%1)+?;B978*;3;#58;B76",3CHD-BD6"-;17
@r8174
TCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGNGCTGCGT
+
;;&+7=#:F9&7&2;HCA("#%'6B1GB&'>#%=9$#1#9#&;C2;/'?<"4@799/A*7/37E*7G+8"$$
@r8175
CCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCNCCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCTAGAAAACGGGCGTAAACC
+
<G2.D35<<.($6?)A6$$1(B*1#'%*C0*?&':!G+0,&:F-&1#21%#;AB%86A8$&G0G0D'C6)1,HCC#7?C-60?&9!$,8A!/:;&GGB)(-/0H(1'&=6E%B'+)9.9E;9,2B3.5=D:/A8A4;61>5#F;>;7!5
@r8176
CGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCANATTGAGCGTGCAGCCAGTGAATCCCCGC
+
5E?/5'F2=+4(.G:9=#%%.'0*1<+F>1E29+!><%*$>02,>BFB29!,46@)B*C)7F23.A;(-BD;CG>-0/+(&(@>9/',7!(%.!?&+84+&H"=&/<E+-@1(0
@r8177
CGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATCAACTACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCNACGCCACTGAG
+
A<FD2<#7&;,-45?9<H59-EH'/H#!;BGA-@7C)&+=,.2$H<::;7.;(0B<?,D'-#.*>%'!%0!#),./C<E8)?1-#-)!@,)1EDG*<34,A>:F"@:4G=?.%/FC&:(A7;,71!6
@r8178
AGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATT
+
B/D?F?$<C+105F'+1#EG:+))DEB$8.H;-0CC*7E+G
@r8179
CTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATGTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAG
+
GE/B"5"$(=5-.B@A?-23=EB7DAB&G&<0FB'?'33/')H2.*DG23;&39E%!6F5@7:G">#?3/6:8B"/1#7>+G@%)0-D(A%%91*7!C26895!1&GCD34$%(;?1@8,:?'$)&.#(8<"%%)/,<#C56%F88$<-8'=H9H:+C?E$8'9<F4$&6A6&<<1?@GH@5B9;%%F';6,.0=EA8&A(0$HG4?96)0-B
@r8180
GAGAAGNTCGAAAAATGGGTGGATGGCAGGAAAAAAATATTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTNTATGCGCTGGCGGCGCTGC
+
*%#!"%!++&%*!!!"%&&!"!''&+!%!!$'($!+++""**$$'#"%+%)+#+$+)+'&*'$#&'$'("*$&'*$)("!&&&)$&$!)'"%!)!++&)&)"(+"&
@r8181
GGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCA
+
1,1H22=C1.6&$E5?';.(.>8H"+GAC9D-@%;;*097<6G
@r8182
GTTAAAGNTANCAGCACACAGGGTATTGCTTANTTATCTAAAAC
+
($*#'&&!!)*((%'&*++$&""+&*(%!)""'+$!!&&('%(!
@r8183
ATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCTATTTCTGATGCTGAATCAATGAT
+
=,GH)21<8(*34'7+?F$7?'288'(<@61,<>E%<4@5@20,-D(@G!E6*9*ED
@r8184
GTGNNATATNGTCGTCAACGACCNCCCATTCAAGAACAGCAAGCANCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCNGATCTGCGACTTATCAAC
+
%!%#""#('!+($*&&''$"#&%))%("$#'))#+#'+(&')$')*&+(#!%)**'$'%))&#$%#&+%!)!!+%""('%+!(*")%+')'$!*!##")$%''
@r8185
GGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACNGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATNCATGCTGTAACGCCCGGCTTCATCCGGCTTC
+
+(AGB!*@!+E#=/.A;H:F857-HH);:'6E8A?:<&5.1!@E+DC/965/"6(%#;#;'<'/G!?9-A.33)0,(%"-+/3H(B#''*E9H+;F5-(!)-3?3*<.9&1!:&F9+.-?,"6FB,8.,E;=&)<*9H9;%$%CB>!0$18?#<15$*07D4>9#A>C8F57;1D),
@r8186
TCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCC
+
*H3G@$HF?7>$62&/:%D;-"@5>E,9HAC"<3&8<EEH.9%+87F1<6';&C85530*/.>5-/)%''7=%6H5,#3,H;73D:F'$,DAB&0<@>&;H%E8$#0;;G<6%9
@r8187
NCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTC
+
$2(H3)&;=.);06A6)20B?4!7"A%!C:C)3!2.)5C@$:5";22;6388!/'A"1':7-2&.-&G::.%3;>&&3?"?%9?:+
@r8188
GCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGA
+
6BC9,6<3#2.8*"6?/=<9981<E<#=)F,C#4#0=E@44);409"!!G,FF=#E3@D9H-+/)+=A?3#?BA-$!GE3%,6;+7H)06%4*0%"=07#.5F$5D-G0,#5/5H?F00?/++*<:&3A+/8C<::16:
@r8189
CTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCNCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGA
+
C=!3,>4&,D6.;?*A02>1"D+H4%<F,18BC&*%F(37&;A2&1('0G?3ED+E/B,G'EF/=FD656;=;<!H1/4&8H2"A?-9E?8&7C*;@+,7927>2E'#930!)!(3A6EE=26G+6E>#5E)+<=6$3&@49=4@#:"C//&H1)::=.D;F+H
@r8190
CAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATANCACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCNCAATATCCNCGTTCTCCTNGTCGCGGCGNTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTNAAATCCCCAGTCG
+
%#"*+!&+#*'#!()&&(#$))#$$'$()'''#"%*)($%#!*&(*!#%'!+&($&*&(+&*#*$%!+'$$')%$%+"'"#"#)%!+%$!#'&%)+$$%(+#'&*"$#%*%*($#""%*%$(&$'!!%()+*$%!+%*'')+%&(*&$'+%'+)('""#!''(*%!((#)($(%!("**$$$%('"(+&!($%""((!&"++"%)#&"(#"%#(%)((!*'*!++%$$+!((%'+)'%)'()!%%)*(#%%)!&+(+$!"*&*'!#()'*%)#$*%)%(*&)"!+%&##!*#*%&##"*
@r8191
TCAATGCTTTCACCTAAGGAAAATAACATNTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATNAGTGCTTACTTCTTCTTTTTGA
+
,A.BD)';4=#81&F%H=%!,=(07,+/@@<;2&D+EB75//HF4D>&<40*,.;:+7(0@(D5.(>$*<@0>%8;>%53-)9?=@6>/C
@r8192
ACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTT
+
F2.,66"-52)&,=46.G@?120:0+?%>-"619&7,:(7&E:EA1&A*&
@r8193
NCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGT
+
%24"B:A,!$$F#54(!*5%'CH01#%0");%?+E%*D3155->H87DG+F*2.$/3).8?1%*%$&B&4>.'
@r8194
TCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAA
+
07::=?/5,!+4/E0@$45(;H0A/?3*2#)H(B%ECF@;4.D+1B=/6)5<B<H@%E9;%$D4>&:
@r8195
GGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAACGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGG
+
<*16#%*6$8%;.G$/=/E.F2B7C$C8$E1!>:8"!&6C4@62"B@6.:?=18>1?CH(,:F2$84?=(<!<(";*C.;51/8.&:'E!/A4F?>@<?8
@r8196
CNTCNCCNNCNACNGNNCTTCTTTGAGACCATCGATGGCCATACGAC
+
*#)(*'*#'#!$($%!"'&+'!&+""!$#&!'')!&($$+)&$""%(
@r8197
AANTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCCAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTA
+
E2<!$%*HF70-@53"(%HGF9)0AE5>F'A<?4.F<-+%,@);@<3.>5#?A,7'1"<C=<#20F+/<&)5'368-79$33"G28*)::CD86F62GA+;%86-A"0)&;4>1(&/?6B<E(F:7&
@r8198
AGCACCAGCCTCTCNNNGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGANTGCCTCATTGCGTCGCTTTTTGCNGTCCCACAATATTTTTTTCCTGCCAT
+
##'")*&#''*('"%!"%(+#)'$$%+)+#)!)(**($*"&((')&!$""*)%&')%%)!&*&*"+)"$%+!')$))*#(#"($#!)('$)'&#$''(!*%(')**#&&'#!("*"!$("(!!*&&%(*#&&'$+($%(((!+)')))$)**)+(
@r8199
TTTTCAGAGAAAAAATATTCATTATTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCANACCCATTCCGCCCG
+
-#G5A5@**8*:88B8H+A>.&.48""&"$7739@D2H(--H+"*>9?207A9-G7;7(:5E77=@@;6B(F30#8D..4;E(*BH&;)74'.
@r8200
ACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTANATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGA
+
(7.9G92F71/%')C2%)"=*45@B&:':C=/(<;<%((A:)&)1E,6@;.3G:*493D"-94/)?!2E@,5)E?1'"2H37C+*D'2"?5)!>,7662966-1'=9?&@#3G,8.,04C0"D4C@?
@r8201
CGACGATGAACAGACGNTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACNCG
+
F#;'49%%E%=!#59,11@46&GF":?1,61*,()+-@>,87C'5C&'H:%F(F>!B
@r8202
TCGGCAGCTTCAGCTCCCATACGCTGTANTCAGCAACACCGTCAGGGACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTNCCGGAGGATGGCAGCGTGATTTCACNGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACG
+
GD<H912!1<;"'''9&!CF$/'<D8(3#3196$B0D.,,D(+A1;$F(+4+D;<7B-))'#&4H'/:)/)-)=&:*F>6(;"5<-G),;(D=B"1:+;"G)+00)8(6AC:-(+A+6&@*G>%'*0)G$@0'0*<##3,)D05-3C(2G!A;78%@>"%403//1BF<;5C0=GD>)-$B'9F:;A5/F@'1F9=@;;?(FBH7:&=7"+338$7/D*.,8$!(9DB!=")'D*5D9G=5D,@AF1@E4!8ABB?HFC$!3B@2@+272H&GC6F?<2+<+++G&:.GA#6?<F?5=3A%FF+8@7C&'D
@r8203
TCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCGTTGNTCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCT
+
<:H(#5-<5,*?</G8A>E8A?8+)4>-3EG)E5E%!/,$4)%!;6>3',%*)<?F>.B93E*=8?4-3@0FFB/E'D$15G;+$9$G?*#?79(,B2@#D4H?>7
@r8204
ACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTNCCGGANGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCT
+
0'+-%<4=6&3BAG20;201H#$*:)79.2-#703=7'*-)1+B*>7<69:?)D?()31H->4F'F!$%A:2?@199+"0;#(F*36AH&3"&%-/A8
@r8205
GCTCATNTNGAANANGACCNNCNGGANTNNNAGNGNTNTNNNNNTGNAGNNCCNNAGCAC
+
###"$$$!#"!"!$$#$!#"""##$$"#!"!!!#$"!!!""#!"$!!$$$"#!!##$"#$
@r8206
GAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAG
+
4@=$,%E64(;3;1$?=7:>+9!"8'BG!(C&@G(+5&B!@H
@r8207
GAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACG
+
&+&1:A=8+.F3174!#.AF,1<>F>;2!E+-+54%4E'!'$+E2
@r8208
TGNNNCCGGTGGAGGCAGACTTGGCGGCTGATTTTTGTGTCGCTGCAGCAATCGTTTCTGACGTTTTCGCCGCACCGGCACTGGT
+
*("(!"#+(##&)#%''!!+"!&%#)"&&*)('(&(&&"*#$&"!()%$+#*!%+$)&$$'(%'++"$*&**(*&'"$&+#+!&$
@r8209
GATAGTTGATAGCCNTTTGTTTGTCGTTCTGGCTGAGNTCGTGCTTACCGCAGAATGCNGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACC
+
%#,6*6B97H3F9(D:&:/+!"(56)=9%@$/82D.-#)FD#7,G'E%1>%A*1#+D0%9+')6&*!8A/)'"/"%A6-4/5FCD%8.@(7078C+9<)7>1!0-?(?%-9;<'</,1
@r8210
GCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGG
+
&%H3):9?@5'70+H.40+2#-/$(',9#21,,(D7H!46%5635<#@H<-67'(0$5<23B)*35+45G/-?%#G;,GA/;)D.!</.9>.32<&1@"$4+!
@r8211
TGCACNTNNNTCTTTNCCGCTNGCCGCTGGNTCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGNGGATGAATGTCGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGGTAAACGGGTGGCAACAGTACAGNAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACG
+
!&(!*"*!!")!%'%))'$*"%%&"#)(*)#*+%*#(+%"#!)&&%$#*(*&+"&!(+!!')#&$+**())$+"%#!%&!*'*!((')*#+(+'%#%$"$#'*"%)()"(*$!)#*'%%#%#++&+($+$#))()&'(!&%)("+!$#(%+"'*!$(%#$($"'*%(&$#%$)%+'*!'"'+%)(&+$)$'&!%(%"'('$#%"#!"!!""%#*)'"+'#$'!%'$+*)!&&*+)(!$$$""""$!$$"(*#)*'%))(%*#&('&*%""*$$#&'%+)$+#%"&!#"$&(#!$$+)$""+*!**"*+!*
@r8212
TTCNGAACGNGNTGGGCTGANTGACNGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGC
+
%!'"'&#%%)''+#'("!+')##'#%"*%!'$#)%+'$&&#'%*'#+'((+*(!+!($$!''"!&'*""%*++'$#&!)#**$'%&+%##
@r8213
GGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGANATTGCCAAAACAGAG
+
F07>6!8<.3AG=$'01?$=$(*E%23F$H@B6-:9DA&=:@,HC&F35D:'!;41;<"1
@r8214
AACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCC
+
CG!.8#!"<*4CC9;%%?""0BF>F/7$<*$'2:6%8";373!=-;<G'F.%"3:('*E.>)01B>"(%D+#+&;#G6"3=/$F(5<<0*D"./&342G>"E*0@C
@r8215
TCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTT
+
;3.6='7'$=+$%1HD1/E!-/</&5-5*C#989/7;H$(,0*=)8'1,G$+2F2H)*8:?G<'+<=E<+
@r8216
CNNAGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCNCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGNTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCC
+
&##+*+$###*(*+&*+'#&"+&$("#%!$!#$"!%$"$$#&*%)('&'%!%!$"+())%$"&!"!!)#'(!$%(")!'#$)&!!''*)'$(%#(')+''$+'!*"()+$&"#*+%''!+*)")
@r8217
ACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCA
+
D8";!EE;.C%"4B@%14$!8!&.;&@<<8?&2-DD6B-A@(G!+6&*&G03*BG+71DCB8
@r8218
GCGNNAGNNTCCNTGNTNGNNNNNNNANCGNCNNACACGGAANATATNGAGGNANTGGTTTACAANTNGANGANNCAGTTNGAC
+
#!!!"##$""!#$#"$$$""!""#!$$"!$!#"!$#"!###$!!$#"$"$"!!#""#!##"$$#"!$"$$!#!$"!#!#$"#!$
@r8219
GTATGTCAGGTGNGATGAATCGTCATTGTATTCCCGGATTAACTATNTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAANACGATGCACCC
+
:'+F')E,)FF36,1?D?E+,B4(=-+39)8C#6E/7(-<+%%378<>(@;GE>#DG/CH,H$%<HHB<'0?3%?C.=39?F.+$(B*=*>FG")-.=5=(2H<512*31
@r8220
CGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTNT
+
<4)/B:&9E445">C7,(*):54>,&>!?F>=EDH?;B5"/.4<,&:14=;D'D86F=72D@4:9"14.,$'*,@6,=5*0@!8:F77H)G&0!
@r8221
AGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATNCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTG
+
/5%G!?+??/0%)+'?D9?C7:#()?>0%B@"#>45>6G1(:2+/3-@"3)6691:H'14'8:G6H6B12D0!E0#'@#!CG:A%;2/?6/4B3)*/0+4%1-E6A=:?C=)#.8677/B<#1/*GH<4B.H$!2,031E;($9D'5;#3E,6@$&1"-F-9C:!D%B+)1(
@r8222
GCNCTAAATCTTTAAGTCTTCCTTCCCATGGTTTTTTAGTCATAAAACTCTCC
+
'*##+)"%"#)$%"$&)!%%#%!++$#'$)("'(&%#(##*#'$%#(')$!++
@r8223
ATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTNGTGATCAAATCTGACAG
+
>=>2/</'C!78/,#C7&4F<$=@+H#-<(:@54!*-85405$G9,EC01>;5<9%81B3
@r8224
GNGNNCNNTGNNTNTTAATANTNCNCNGNNNANCNNGTNNAAGNGNNNNTCGNNTNAANNGNNGCNAANANTTNTGGCAGNNNNNGNACANCNTGGNGTANNC
+
#!"$$#!$$##""#!"!#"$#!!$#"""$#!""#""$""$$"!!"!!$#$####""#$##$$!"!""""!$$!""!##"$!"!$"$""#""!"!$"!"#!""#
@r8225
CAAGAATAACCCGGCCTCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCANTTCAGATCTCTCACCTACC
+
CH,"ABF>6%9A1599981B171?7E+D=<"61C?8A,'3+$3@37;-8+'@1#6C7#B/80!3D63,;5>H!%=6*$!F$+6AD.(&HB1;=*!H@E'$C7!?0<6##F.6.<8%7F5-;-/.B1B';);'?
@r8226
CAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCG
+
>&9GB3@E!C0F!$1A;1@G:?),17./$0621D*:.*5,@)3HC51:B>))AE;>841$F:"D"$E.=7#'."$A5%8:7?9#A,.-";*0&';@-</40!?*H;&42=*E(>)@")2F(#:":G'/!<*EG0*?B%/0A%$1';2"+80;>C9*9*:G)/"7A:;0DC5*,!G>5CG*/7ED&+D$+7+4#7F;?11?A?B(/=4(<G=280'6F4
@r8227
NTACCGCCTGCCGTTAACCGTCGCCGCTGNAAGGGGGATGTATGTCCATAAA
+
)-31,F0G>9+39H13"+CB*("89&0#G-G>!EC74#@/#:C)?6>E/H1"
@r8228
TTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCGCAGC
+
E?6#@,03&*C/#++8<%2A$4;H.=8(,;HA@H"+27D#E(?;51E%9H+GF1$
@r8229
NCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATC
+
%+)&$"%!)$#*+$+%'&*+*&$+%%%!*"%##!")($&&%'
@r8230
CACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTG
+
.2%;%263)H+D1")=E3#!02HF2D&A5B'>4G43D6C!??&/59DA"128;;2$'#8"18+2+A<+7=A*0A
@r8231
GACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTNACTGATTTGTATAACCGGTCCGGCCATCACGCTCACATA
+
G74#/H@.?D,>=9#<(3C%.,".(=%+/)D);%,H9;)<7G>B69BE359CB"1:>AEEF@82E7<-1(CB/80$#H5F0:
@r8232
GGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCC
+
-F7?E%3-'CB5C,C<'"8H-$E!!.#?:A,D/%E53.&&E?7-.#'@A5;A0"&H-!#-(1,919)<A1.HA*4@<'+/7-'E,!,(!"2C/>67(,4/H.)?5@/F-"./3
@r8233
CAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCNATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACT
+
;2>*;&3*008%D7A:5!7+$9H!>=9&7@,66D(33#1@1>C5<1"5>&;$=."HG?FE242A77A9;G+!@=A<26(/?H<1C*?A:68"6DF%8$B=2CB;0F>@;"=#)/A;3.)A
@r8234
ACAATCAAAAAACTACCTCTTTCAGCGAGAACTNATAGCGAAATGCTTAATAAATGCTCGGAATGTATGATGCAGATNA
+
*D5'*4/:9:-,<&&7?71@B8D.$&::6?"@@;H)&8+B'@G()H"@##65$1@G?/"<2-',EH"0$G?+=9(+#,G
@r8235
CGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACG
+
*?B29&;,"G?@&#%*$%7G51E8->3->B#;"GD167!!04<<>+F,.*F+G!$$+<&309+$995?=B"!")F
@r8236
TACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATNGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACT
+
&@(C(5-4G7'0=@<%#H1!6-8'(%@G&6,#C54;.*01AA*<D1/8,="7"0?G81*2C)E2#7*%<9):8:<G-&E9H%7.3@7=&=8-<!.EB,5HC9C:8F7//!6=46'C?)@83"=@8";,"59>F*=@"<.@$??)94
@r8237
TGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAN
+
+9=C4;."A;B>@*F038G'$6D)2@6$/=048>D&E8E%@0#)906G14!F7!.(+&G,/D#>H7H%9G%.=H0*1/>?!0-<C>?+H%4:!3"7#-,,H-&EHE2,!8E7%5:EDD5E1H!A=5!:5;>F;6FC;D:AC5;$%5<G!:78<60+(;.46?8=+@;'C81/
@r8238
TTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCA
+
8(82/9BH83,#.,&!'2'':9'DE+B,?@<C&@#CHC=:.B**5'DF
@r8239
CATTCAAAATGTTGTCTGCGATTGACTCNTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACANTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCG
+
17B48B40@#!'2*#1F%>2.(?E.+1E).6?-F+.:!''<2>B0D":')/1A10/#D;;/?,$>3+,%(?("<4G/:4<C9@;/G#1.6!3,'>B2>"$3',<0DE"!<=78%H5F;>6%*!?>
@r8240
TGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCNCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGG
+
8<7%,.0'4!H(#7H)E**(*6EG>9166(4";6(9E7!<<:8"C275;)/+F<6>"@*GCC&H7,;2B*1?<FA<?:*59,!=044(7;;;:*D+>?+:!4$.*
@r8241
CANNCATCGAGGNTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGG
+
(*%%)("&""$'")&+#%&!$%%#$%$'#!+$%$"!!#$))(%)!!'$*$*"!(+((****#("#(!'$'!"$&$+"()++*&)!**$"*!&$#)"'"#$!$+
@r8242
GGATGACCGGTTANAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTNCGCTGACATCATCGCC
+
5C)B=H+4%?B+0:'7!@&(79H/';4?D4."(<F$"=?'8C%#5A0>H%>A1>=,<!'28(=8;G7#0<H)/$7<;+AB89?*7G>*-3%1A6""387<-@1B/*3B5,,G,.$1*.A#9A,/5%B<*4/B&#'*
@r8243
TCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGC
+
0&#A&D'/F;&/G7EBH7*4.#H5$&AH23?/6>C+G4%)&4H3$/8E:@4=7
@r8244
NGAGCCTCAAGACGATCCNGAATGTAATAAGCGTTCATGGCTGAACTCCNGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTA
+
"?6;<0$6*,991<;5;1(-3:(.<+&1;(G(1**=?9=8;.>=9=/)189"GB!8,(23(><(EBG:'E5>B!)2;-C>3?9)=5.1#<'='5
@r8245
GGANTGANNGANNGGNNNGNTNTNCNGGNNTNTNGANTCNTNCNGCNNNGG
+
$"$$#!#!!!#$"$$"!"$#"$$#$"##!!$!"###$$!"$!"#$$"$!$"
@r8246
NANCGAANNNNANCGCNAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGANNAACTGCCGCAGAAACTCTT
+
!"!$$%))%"#*"&*!%+!))"+!)(#$(##)%)'+!$""*"+$*((')''"#))!)'&'#**+&!$**#($($()(&*(&##'!$)+)&"*+##'%)"+"&**$#"!&*&"($"%%'+!*"$##%+#)$)#$#"$')&%*%
@r8247
GGGTTTGATGACCAGACCGGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCA
+
*G@(B'%A"81E*$%;%#G?B1#FG5(GGG?%$4(>27-!>*:9440D?&3<8G48)=%:@;$66-C>(#7*,<$6F&?/0@
@r8248
TTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCAACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTG
+
;,="GA%6*26*=9?6%$$;E<"-,$B<'E!+;899-A28!,!<#?C)/HA1(!4->B%G00,C244$30-:'>?6%?#2/2'1#>/>%/556"5,@G$:*3
@r8249
CCGGAATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTC
+
=+@)*/0519E4(&$DF%,/C,F&1C13;<7/#<D&C%32.$'BE4#B.1AAE"#$$CF//,)A?>-/7/@?31H/;2A/$&?<4!6<C?D$$("/>$F=G=#:?DC=2=D!2.;,65(%8>3:/H18<G00!-:B,%2$(4C,#:"5D*)B:=5<??4;(.09C1821!!C)<H8D3?%+03$?
@r8250
TGGGCNTNGAATTAAGNGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAATCCATTTAACACACGTGCNAACTGTCCATGAATTNCTG
+
+#$++%!#$&+#$*##"!!'!&*!*"''#+(#)&!!#%(#&""&)!(%'!&$(%'$+"&#')&+#"(&+%*)()(*"&#"&$(*#&%)&$&$&)$##'"!""("!"##+"%()(%"'!!%%!($"+%$#)$+#+#!+(())
@r8251
CGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATG
+
4H!H/B;?%C*+>1;94).(3(73G=CFG.G<3,<>B4)F52>948E((9
@r8252
TTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTT
+
40'#'F$8=;;!'C/!;62@3(A>8EF*<-82C6%+0"C'D72A;-32%#>:;,8@$%4=)$<+7B6#H-*0?@;#,!+=F7"
@r8253
NNTAGACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTA
+
"+##'!*'&'&#"*"&!"&$%(+)#+%$(!'%+)&"%+#)&!+!$
@r8254
CTGATGAACTTGNTAACAGCACCGATGCGATCACCGNCATGCGTGATNCACTGGATGCAAGTANACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTC
+
)5"80(=;GB2-F"=4+"$2CD21CA#*()3)>:$$9;"$C)=49>2G*+G4#'H:DEAB!",8!'6./H58'>2D8<>B5"G02/975;C**7F&%;A*+#;;G8&H90.D7&?B
@r8255
GTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTNGCTTCGTCTGACCACTTAACGCCNCGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCAT
+
%@0&8>!D%*E'=!H12$-1:1$DG@>,E.4H@;/"H7<9:.G+,&/;<4D%FC)7%=.=:$33;5@.8F#@6%%@9')1F$G'#EC:0:GA$C(+1-40CH9715=+8&!/'74@3FB&
@r8256
CTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACANCGGGGCGACGTTTTTTGATGGTCGCNCCGCTGTTTTTGATGAGGCGGATTTT
+
F>*%H:)0!33D//;/+29F+1&+*5:%;5;B0/@H7#:*+#/,)=44.A;:$/:+G>9.1C;E$%70:E2/-5.D>/D)/;7$"2GA*;*9=$D*3+
@r8257
CCNGACCNAGCNNNACGANCANTGCTGCGAAGGGCGTTTTCNTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACC
+
##")%$#")&$('!')''"&*'+(*!(("!**"%$'**&$)!+)+!+(*")'')'()#'&%)&*'#!"+%%(($%'*%"&(!+"*%*)!!+("(+#&$+%*$+$'$##(+#"+$!(%$")"$+('#+%&+%(%"%'+$$
@r8258
GCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGC
+
=74C1,9C)E,GE0H!B<AF1=?*E*H-1A+6H?-?44E/+
@r8259
NANTNNANNNNNCCTGNCNNNGGANNGNNGANGNTNAANNNAGCTCGNTCGGNTGNCANNTTNGTNNNGG
+
#!##"!$#""!$"!"$#!"#!!$"!#$!!$"!"###!!$"!#"#!$""$!"#!!!#$!#!$"!!#"!#$$
@r8260
TCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTANCCTGTACGGTATGCTCACCGGGATGGCGGTAGATATGCAGANTCTGGTCGGC
+
2:4#@7@#H4E12C)@/F9=:$F'19*/.=E!?:<&%=<1E(-@;)0?A6D:,+##*?'?/BC*,*<4<+#C84(0&.;5"355G?31/!F,+-/>'*0"F22E550<)6,EA3F=')$&9%+CE%:AH-'2?DH!B7G8F18F;H$A,;2!7=A
@r8261
ATTTATTAATGTATGTCAGGTGCGATGAATCGTCNTTGTATTCCCGGATTAACTATGTCCAC
+
(-*)-":904350;-=5C16-G(8%(5F"%6%:4+?E)A2EB0%-=:1!H5"@70D*?A2(1
@r8262
CATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTT
+
.67H?65F>2@>&>:HF,<"1)4G:0%#*'AH%*E)8F'";</;<8->GE)233.9@;7"/
@r8263
GAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGG
+
G)*@;,E":&:C*<?1?"H)<*?.H67('*DA9HHFE?DB$;B?+/DH?','?@B;C3F/'2B1'5*:><$H$H4
@r8264
CGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGT
+
;+G9B5B4>D6$++./:%019);EC>/7G%"A$3+(&)1);"
@r8265
GGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCG
+
++1A;=>)/!(E<(6/(>)6.9C2=5*,-@H85'"023HB>=CA1:4B"--B?;:?7HE4!.F/4?:9/#0+=$0+31;+C!/&C9!9'#
@r8266
GGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCAAGATGCTGATATATTNTAGAGGTGATAACATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATGTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTCTTATCATTCATTATGTATTAANATTAGAGTTGTGGCT
+
(&?E0/G@+)"-((+$)&0#<&125)0>B1-$CF92?:8-C77G7!=H!G-G(B&50))3C$1FE'?@H;?,!3&>'6")7<5;+>C6>9=5??/#C;")>)$4A$*,(%'6D@53"E#6";'?1C:7B-$=6-.'#G=3'F#?7"B6$(!;9'#&2:4C73,;:;G<?-A1F&.2)!F<C5=BDF)*G.8F#!36/,D/A'9)FD8;!C..=&'&*
@r8267
AAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATG
+
0H$$8,8<+%@E&$,*B0/>"C!<H1E&11=HC0/GHGH?&29"-&6#)'61,;#7.D+
@r8268
AATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAA
+
'#+='<371"-*1(+HE>+E4H*"A$:#(2+%4A(/%>8C!CC&9G=EH(%GEBAC<.0D,
@r8269
AAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGNCCACGGAGGCAATTTCTCATGC
+
()@8)G40F);<'.9!::>1C+?0!92A:FF'G7#,,&3+'*809-3=+9$:3)'(:@2.5G77
@r8270
AGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATANAGAGTAACTTAAAAGAGAGAT
+
>7<D>'/#<;5&*A7+7F18H?9/6$0)F1?/%>!(C2,?-=H7G8!4%2(CF0?3%3H7)"#5!+9E430?#=?-?A<57:E"7B+H!68$#D-*C-9GD42671>?!&<C
@r8271
TCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACC
+
C%9G<H@8*(>7/!#=H"CD#!)?G<*D%G,E*&<9:B0*-1
@r8272
CCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCG
+
#F@-=$%.?C&@4.=&79=H=H80>9+:;=$>DC8,':-C')
@r8273
AAGATCNNANTGTAANTATGNCNAATGAATTCAGCACAGACAGTGGCTACGG
+
)(%%"%("$"!(*'('&)%!&*&+)$$"$#("+"*(+%!'*"&%$()#!))#
@r8274
ACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGC
+
(93'#C5E(!+.F10/FE"+)3&#E#4(>B(FCB72'H"F9@;6(C#G<?>85@3B?B1/C,&-A="
@r8275
AGCNTANGGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACANATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGA
+
)')"%"%!%!'+!#""%''*&(+("'*+"%++'("#"!%!$%($%!%*(&(&)("!*'+(!''$#&$#+)&%!#$""$")&&"%)!"$()$)#*"!#(&%"!'!#(&"++'&''$"#*&'$%&!!#%!"*"(*
@r8276
GGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGG
+
)>9>473$/*A;+6EB<G%9@%<:(88&(,/B#,:.:-)!,-+5+1BB9&&:/B2@*84:-
@r8277
NCAAAGAGACGCCGTTTGGCCTNAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGC
+
%&*++#%((%"!($%"'&""#)'!')$*)*(*)#(%$'$*&*"++%$#$*)(+$'$+*'%"($#'+'&)
@r8278
NAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAA
+
#9AD,A,?8(:.1&DFAE;@'D<:=.$B?'E4'C/!27G$9H'C':F()6'3(<E<&;></H;E#C,%4=C;<8+89232<C#$!4;#
@r8279
CGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCA
+
%:1"C@%@C$@)@C2+:%@H#006#E?02)/@@+1C/7?"B5-4@),7C!*72(:$*-)*$2#3?%13+=A)8@A#A-'
@r8280
ANNCGTGTGGTGAATATCATCGTGTNCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAATCCGTAAAGGAGA
+
&!$#++$''(&)&+*")&*')"&++'#!)#'*+(!#%('$&%!'''#"!")&&#*%"&"$'%"(*$%&#%$#)"(*
@r8281
TCATNCATATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACGCAGCACATCGCCCGGCTNTGCCGCTTA
+
'#%%!$%$++*"*'%+"$&&$(&%'($")(*%"!$+!!+)"$!"%(+)#+'*')!#"+'')*+!**$!)+('!$(+")*""+%#"'+)$+!($()$$(#"&"&%)#%!*!(+)%*+$&!*$$(*%%(%##((*"'&&'$%($*+#!)%&+(!+)+#&**'&!"!(
@r8282
NGNATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTNTGAAGAGGATCAGAACTGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATA
+
)&#+%$('(%%&&#&%!"(*"$(%&"+++&''$)%)#%#)!&%#!)"(%!+*+)*+#$(++'&!#*'&#)')&%+!)!)$()+")$+')'$($%"+&&+$'$%')!*''!%%&&+&!#+%"!+)*&$*&#$!$)!%%*$')'"*''
@r8283
CTTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGNACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTG
+
($H<1-.7/6+/$45G*2&</7"A9=):7&;DC5%'69-@F</A?C&3/<#8+&A;D*%4H.2&,8*>45%/<)?81C<!$D119,#5EAD=H"G%=F%C/0+/4,A$+0F5C,;;@%.,+D,D,'G2C:4-A:17!-3&-C&H3
@r8284
NACCTGCATAACCAGTAAGAAGATAGCAGTGATGNCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCNGCTTATTAGTACTTGAAACGCTTCTTCAGAAGNCTGAAGAGCTAATCGTTCGGCGATACTA
+
",2H9*G,H:-$8.)A4H9A>B#)=:;*3G<B/)-?;-D?3D6-+03?=-!*H+)E4135)59("#-6(F><+9)-=.3D;D!G+*G19+39F5(,&22E30+@'/?=H@15;<G:0"EG4'<9/%!@$(%2>-5>@+1%8$'4E+$'<*E;:G>F+1;8D%#H!=>!!#*<1&>5;E'>F3G2H7?0#'(8:G6-5&-E@6=)H0$6*G1&)/)698CH)"H'""-7A&E#$64-"+&/-+A6A,9
@r8285
ATCNATTGGCCCTTTGCTGATGGCATCGATCACACTCAGCAANTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTNCTTCCTTTACC
+
&&)"'("+'*$"&("!%!*%*)'++%*""*$*#*$)('"%%)!'#)))%*"!")"")*!'"$!"+")**"*!"($%#$%"'))"!%!&!"#%*)!%)!#+'#
@r8286
AATTTTGCACGGTATCAGTCATTTCTCGCANATTGCAGAATGGGGATTTGTCTTCATTAGACT
+
;<:59,H#@4A:>64.-*H=5;#2"0$71)D+?8#$,65..=?#1&B7.:/&>.90&DC9!;F
@r8287
TTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTG
+
852(,3FE;%,&/,0H".99+E9<(3>.$4AH2,7G;D@-@E?F-&53(7-C-7=#(0:<$697
@r8288
ATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGT
+
4&FC6=@+9.:D!#$0F.EF$;1>E1*)>-3@0C#!&3$5!=C4"E::130#A&6"0*."'C7%;;B!&)E1'-A8,=9@!EH78!#!
@r8289
GAAAATGTCATACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGG
+
.8B"A$H:8*%<)C12EA+8=!9/#HC#$?;'@>FF(D%.)"#;"G':7'H'<C71.<,!>62-!DH<,3#'=@*A-=+.:&
@r8290
TATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGG
+
B&1*=6'4)-B=7#<:=FF:5;(?-<C-F%='?@$*C);F*;=$),9.#&9D6<E7'
@r8291
ATCGCCTCACCACTGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCG
+
+044;%5B2=0.$20%ED$#DB!8),0)"2%1<:A92/#.7=-4GHB/<G2AADB)/712&(*$?/="<:
@r8292
NTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCNTCATCTTCTTCCTCGTGCATCGAGCTATTCGGNTCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTTTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGC
+
"+#)!++((*(#*(%"+$+"!###&!#&*#+$%&++"#"'")*'$(#'!!*$*!*%)()$'##$'#!()#)($**#'("(+'+!+!(*"$+$)+'(+(!+#(("%'#)#')''!##$"*#!$&!)+!)!%$&'''"($%%%+%!+%!'(!%(!#%&%+&%+$&#&'#($%)("*(#+#+%$)$+)(
@r8293
TATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTNCTCTTTCAGCTCTGCCACACGGAGCGCGAGTTCTTCTTTCNTCCCCGTCAGGCTGACATCACGNTTCAGTTGTTCAGCCAGCGAGCGGAGA
+
EG&;=FH9;H,3/>==2+$3#DD"B-+$)D(HGD!552@GG<4*(A6A"%.'HC&,E8:4AG5@(4;1$,A>D1(:@49'#B8@$A87(DH8!4D8(G4:D7$BH+4?9$(C1?+):-G#$"3&%G7=&)@=7+-=<A80%'"$<&AB$.>,A#&!CG1+/.'!)*B3102"F8??('G=GF7-8G)"2(.?6.C""4E>>=8)A/6;<
@r8294
CACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGATGAAAAAACGGACCGCGTTTGCCGGAACGGCAANCAGCATCGTTTAACTTTACC
+
0+DE-?0*638(G-@E6)56/;68,B@9$G!<5G$=+=E%;=:633$-,%/>8717?0,05D#')8!(!,-&=:+72#;731$8'"!9%B!%B>E2;7;E,/?D
@r8295
GCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGA
+
+')+'+$##%&)$(&)'(($&&$))!$'*$')*%&(**!'#$'#)***#)(!""
@r8296
NTCATTACCGTNATAACGCCATTACCTACAATGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCNGGCGAACGCGGCAATTACTGACATGCAGATGCGTC
+
!747(*7(DG7E=68CG?"*5>;6(>4<C/0D;&GF5,,4#>@-*CFD1$>#C:@>A>)=3?/=7--F?@E343F$/C9(8:5,@=9:5%.C29&1G=F)06
@r8297
GCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCA
+
4H'(+-="14H>;5CB62&A5//7@F.6$H*#5<EB<=@.#:9#/$-;6
@r8298
CCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTGGGTAACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGC
+
=,C=3G"?5*=H7?4-H6,6$'%4-63A,2B/:3%+%.?3H?%GG#?59DG(@CH=&!2-!-37%:F<154B#0$.%CB(H;";;;E>'/@//*0&-0E*EEA2B%FA;2AE$79#+DH*1=5C.7(;9;H%:A7#:=F0*:15>*%5-!/A!38$#7E%+#>820=F4"'C,:DG-E!</B06'H8&%/B4G#5D,0H>!%9E2(C@C-1$(8(-@:/H3:)/@89HC8174#'4=GE#<"$:H'AB
@r8299
TGGAGTACAAACGCCNGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGG
+
@=5@340H.9.(8@":=C#3B)B.:*:#*7"*6(F:6530%,?FA.!-4.:),:;0=1G?/)G%C+(1>91!?!<<@8
@r8300
NTGCNTGGGNNNGGTGGTAAGCACTTCCGGCTCAATCTGTTTAACGGCTTCATTCATGGACG
+
!*)&*%'%(%!#"+""+(+'*)*'*!#%)$$!*+#)"$&&'&+*%&#"%%(!&))&(&*$&*
@r8301
AATNCATNTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACC
+
")($&!)"*+#$#)#(%"%)*!)&+'!!&%!+"")*%%**(*%*&+*+
@r8302
GTGGAGTGCAGGTATACAGATTAATCCGGCANCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCANCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTNGGGTC
+
88/H4D0FD(D*#"52.D62C7+E9$044(&=*(8&$CH:=1?-556:<3/2<C:.77E%>4<C#='F=,A?GB?2%8=82!2'(?D-H9F?54*'#FE*55#)08/24F5*,<H&%
@r8303
CCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGT
+
6&1C(B3CF-<&"/"1:09GD-"-#$B(?ED0*3@$FEF1@4=C13H?@B7'.7?0:)%<+BE&>,2;4C0)'/*HH$+;.%H&,A1(,2/669$;#>H'/,+.!@H2;9F'*5H>'?
@r8304
GCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGCCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCT
+
(1B%B("4>C4E'1D>HEFH=(D)9829%B4;G&3!5D5'9>9'E%84HF1BA/5F45'(4)0G,;-64&;)&A-"(5)#7>%;?:%;(+-<B067,77A94!,&';9;HC+8;6#D$A:.1A3/*/73!&>@
@r8305
CCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTT
+
=6+4H7--&=&#2?A7>E%05:5/+8H60;1/:9,!D0'6G(4('=D6:@@0B2"!H;&1,<,%/6<&G?$A1/<8#-"/>#G0%
@r8306
AGTGATGACCGGGGAGGATACGTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGAC
+
4A@!=G#H'>@,3H>)+*7D$EG%7>F83;?F&(5?C*F2B1F0442CB0=C;?E.5:A8.29BE"((5A
@r8307
ACCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATC
+
&+%&#*)()*)"&$+"'!*#"&""*'!'%&#())("*'%%*""&%*)&&#"'#*)$)(%(*("'!!)!++'$*%%*'()(&**)*+++
@r8308
CCACTGGCGACGGATTTCGTTCANTTCGTTCTGGTCACGGTTAGCCAGGCTCGCC
+
>CH8=?8$1,BF(F$F$=/=C/8@,9"A=<'5BE4BA+,!!(EF+G!C+:9#$&5
@r8309
NATGGAACTGGCGGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTA
+
'<A*2&4D=3?9DE>#G24)H1C:B#+1''+?2F2&4?../!F($"+.8F0.G'87,'+')433D/:D1;
@r8310
GACCTCATNAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGNCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGG
+
%&4,#9B"0-C"$4G%".?C==7>0H&0F*)C%E+"DE5<D#'D:=.B6+B6E-!&H>"$%/96;<0;4&;-2="@#!GF,77014+<E;#@0HECD8F"F3'<A
@r8311
GTTTGCCTCNCGATCGCCCCCAAANCACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCNATTCAGATCTCTCACC
+
?%3G@"<,--9?")F0!**5!("#3!.%E:%DC*$;8:!0*'+C!#+<E@,!A2:97(6D4!(!G;4:-?/%$%8>%2):*7A1@F"7EG/3!#+D<G
@r8312
GANTTGTTNAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATNTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGC
+
+<6<-H;DG.C62)#,G@'CB(.-=7DDE&>11E9F@#B'"C,EG,4-0F.HHB!DD:.;'7E3><&HF=>00?!#,&E9/458/B@8,%F:-23-2@FC*/0#A5G.:(1-(9-=<341$
@r8313
NTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTC
+
#'$++#)+#)"+%%)%+(%("#+()!&%'!+*)&*!'+")'('#&)+#*)$"#$+"!)*%%%*'(((&%")&(!(*!*)&"%#((!#''$%+
@r8314
TGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGA
+
8;(3.70@'"6+@F?9?(8GF89+D:2*#?,'H2E('-EF<DGH4/,?5@GF%E(/9=%"8HGB)D92@*A5?;H:>//8H@(%;)1/B1
@r8315
TCGATATACATTTGGTTGNCAAACTTGAGTNGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGT
+
=$<=1=8',!>F>G-3(D-<?/8/'9(.B86=C+%9*,)B&5<65?'>G==;&D4@+2!).H3+1;#2E*4<1&C+>=*/"2H8@?!>2:A5"4:&"D"$$)41+*6?@9"7)<#+>"2E,167
@r8316
TGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTAAGAACAGTTTTCAGGAAGCCCGCAGTNCCTGGGGGAAC
+
>.:E8(-D1<@#)>5+44;7""H83+AD.>GH.#>+'@%/2,!?<6EB'G:BH#%G=-7*5*F(<-/5AB2#5HF(5'B54:"*"))!3$2G;E5(8G:.FF="8C
@r8317
GTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGNGTTCCCCAGCACCATCGTGTTGTC
+
4#?%4@%H=@*D//6-G@43>5BD>"4%D&'?'$2$;'E+:/0F$10%G,"(1;4(=@D:>8&#<&C#F<D#73@#((0@'5162@0->-1#&0>D>C@H,;6@+*/AG-%5;%;@&(($;>@.=6C$BC591@2*81+C'C3'.3H1E5'06H**F5D.%;B;4B)4,4?)"'$'7C;
@r8318
TTGAGTATTTTTGCTGTATTTNTCATAATGACGCCTGTTTATAGATCC
+
*<H21E2D-$"'C#*$9#:)662A%5*.9-F))0G"1.'$.7/+%<+<
@r8319
GGAACNNCNCTGTCATTGCATGGGATCATTGGGTACTGTGGGTT
+
)*%'#%$'"#"++'&$%!"!"')(+('*"$$)$*"&*''%'''"
@r8320
NCNNCTTCNNCGTTCTNTTNATTCCANANAANATAACGTTCTCCACCGACCTCTGTCAGG
+
&%&$%"##$!$$(%%*'"'$(*#&)*"%'(*"$'%++#*'(*#!#!'&*$))"(()&*%*
@r8321
CGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGG
+
>:@5-A8/7'G:=2G2>G+>4.F;HB'BHF5.<,E!@"E#<1FDAG
@r8322
ATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCC
+
9%0+@34*"1B2>@%ACA15"(@H:G+,*(8DBB,?>4)8=*:89!-;5*!!$-E$?:-'0=;%H<;):(*
@r8323
CTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTAT
+
-4?5!9+!A6C6'*4(.?GC-5%E<6=34F8<@0'(HB;8+A.%91$HA9:$5#0)+"<4DG';8?$!>2.CG=*/;9%+1'@8E1'-/$3<(=
@r8324
AACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGC
+
D76:?#938#70?##%(D4?5"06>2@'AD"ED;E'?A'>1=%!'
@r8325
GCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCAT
+
47*E03)0(%(CB)2D61<(6B-7.%3F,6"5B:3H(36H'+</B!-7G5#-40"C-F,#;AE:?'305-:.!
@r8326
ATAAACCAATACATACAATGCGAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAANTAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGNA
+
+8'";E:(+D<B+2$-:"E895*-(F?)8)3"!!(D):9$5H84(7/A!G!>)!?4#$2:8@EA8=25<4CE-H-*B1AB'@>,,??1>2)8E&%@A$@3>=01E5G9@2*F?
@r8327
GGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGG
+
49C+,:5F7A#89!6AA*+5<B.G8=>"@!D'D+4A<.+/#C$E&6)*:$A+H(%@-,(0;
@r8328
TTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACCGG
+
*@:@/#E<A<82A-@8+B(A&.A1)1?:*>,;'G=(H?(%(B44#::4#D$8:355,?H4&6':'E!H.=$:B.(7-+:%,7*,@5@0#3F6/:-D"@1H<+@42-&E&B;3,11D%:/5?&#,@73HA@=?>!1-3-H/8D5'
@r8329
TTAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTG
+
A/"&E>&,28-7<?4,-<2$D.H7!(/:8GF7"93'.E%=*(#;G?.E;D
@r8330
TCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACAC
+
*)+$*%#)*+%%+%*%&'$"##%#&&%"(%&!+)(!$*'%++"))%''&$!+#%(#!)*#(&)'$)"(#!#+)""!+%%!
@r8331
CAANGGCNTGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCNCGTTACGGTCNTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCAGGGGCAGGCNCACCGCGCCGGGCTGTGGCTGATTAAATCAGAACTGCTGGAAACGCA
+
((*#$()$'&+)+((!((+#*%!#$!#""'!*)$"!%'(#*##!$"'(*%!"%)!+(#++)'+%('$%%")&&)$#&#)"#'!!$&('$+))$$))&%+'$!#%%%#+!$!$&!$&&'"+((*!$"&'&)'$''&+!)'$%!'!"*"#''(%&+#(!$'
@r8332
TACTGATCAGTTCCAGATCCTCCTGGCAACTTGTACAAGTCCGACAACCCTGANCGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGT
+
*0GB/E,3/?B?>3D3-8,<$&F4(B>&$/*;<)-EA=B<)F0<!?D=),;>BA2"28B558?,864,"F*6E%4G<6.33H)'47:!;'38G%"2!-?2"'D!E%7)34=*:+:,B%2,)E'(<>
@r8333
GCTGCTGGCTNTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAANCCAGATGGAGTTCTGAGGTCATTACTGGATGTATCAACAGGAGTNAGTATGACAATTACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGG
+
2.37C941'>%=.).)@+&F>D8A3F/3:;G<,,FB7F>>7/2DG=?D':>1%/AF30:(14G4%1.-4:$H>'%9$9,.=!%.C2)"804@@1?32'8&;D@(EF@E*:(<F<H,=(58F@1:$;19>9!?+8&562)3CB$>#A(:7?GA4B%6C7!GE)H$=#6C6.H936?H63<3A">;912%29DE8BHE<:-9HG<G'@#/F&,;;1;5=.
@r8334
TTACCTGAATCNTCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATT
+
?4F<035!+,$727%!')*-,DF937(*+-5B;9-EH72;D&GG?:A2&!2/E;*DD"F"<
@r8335
NGCATATTTGATAGTCTGGCGTNACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATNACTCCTGTTGATAGATCC
+
!+"&(+*$+")+%"#('!%$%*'!*%$&'(++*')"(##($$")*'#('$($'!%%!(#"!%"#&!+('''*&%%$%#)(()#!"***+"'%+*("!$(*+)(%$)$!!+()(*"&$&"(&"!(&*#"#
@r8336
AGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCNGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGANCGGCGCTGCGGCGTAATACGCGGCAATTTCACCA
+
1-:-7%&A.8,E&#!ED"<38A4/$6D%D,<@:+2*@=%.(04D?9C"#2A$$/649#$2A&60;@B*+0>$(?'DD)B?8;'82<+>3(6H&F.A2?)+.#,**-),D<0C),106E%+:CDAA5:"!#:4/0645;$"!*AH='36/13GD=*),*.<<;/6585D!2$-.3E,=65!37(1=65@!$73)C#3;52>)-H/A(!60>$AHG-
@r8337
GGNNCTGCTGTCATTANNCGGGAGATTNTTCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCTGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACG
+
%#"%&%))&%$'$!*("#%("!)**%#"$#+'#))*('*%*+&"&*'$!#%$'%"&%!##"%&'"*#$%**+%($+&+%"%&*+*)%()((*+"$(")'+!"&%&('$)#'((!&&#)+("#!$(+*(#("!$&*+&!")
@r8338
NGGTCNNGNNNTNNNNNTGNNGNATNANNNCGAANCNCGTNCTNNTNGNTGNNNNCNN
+
!$!$"!!$#!!$$!$#!"$"#"$#!!$$""$$"!"#$!"#"##"##!$!##!"!""!#
@r8339
AAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAACTG
+
.B5AA@@:1/;#"8GB)0)H5D7*&@<7C#B=!??*$=8-*:=GA3;D"*6>H+(EB(-5%"A<(!1G246CG,A"CG#!"!E;-$%;E-F;$0G1?..89@F%GA$GH#2%G<1/))9)$)$-$3B42*B,B=/E*($1E&05/B60(?#5#D%(;>=7,9G:;B1'D>;25"&3%&$</>63<C
@r8340
CCATCTCGCTTTCCACTCCAGAGCCAGTCTCGNTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGNGACCATG
+
8/H>H,$!,..42%C1=-;.-(.53177:?9(.,053E:C:<3/!E:E2*-/.20-/CG#<:/1;CH,=&")C6<-/=&*$AE7=#CC*6D;-+.'A8*!>E24>G*F=%+08G.;B>A73D7/D9F6)*:"!:-"*$"::5?D#C1:7)5$+/(F389#'F>(D&9*C1G3,C&B5F3/-.8*8)C.:6H9C0>A1A4$7//E6%8HD5G019!<(D5.#2221!B43B',56;<+
@r8341
AGTATCATAGCCTTGCTCNAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTC
+
G4'E=GB39+,)!@5+".'3GD1'6BC9%$'B(:5'&6%213&9(*3,DCE-$-H@+H?&(HAEA:,:E*(/&FA43*"3)>.<?$#!#(!
@r8342
TTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCNAATGCTTCGTTGCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTCGCAGGGGGGCATTNTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAACAAAACCCGGCGCTGAGGCCGGGTTATTCTTG
+
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
@r8343
ANNNGCCAGGAGGATCTGGAACTTNTCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCACGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACG
+
$""*&+(%$!%&$!)(*%##!((%$("%'""(&#!&(%%''""$'')&(&#!!*$'$$('&*(+%&(")$++!()'""(!*''%&('"##''%(%&%('#%+(%%"#%!(&*&$(!&(""&##*!&(&($*'!(#(%*'$$#*%'+)($!+)%*")*'!#"+$+"&*+&*#**%+!!*)%*(#*+"))(*"(+%("#%""*"%!%
@r8344
GAAAGCNTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGACTAACTGGCGGTGACG
+
1C8$68C8%70'!="/;-$%780;/;<B*62!C3=57(!%,>0*&.362(:9*"@&6'99"<!$59H/D=<.CB&6=)AD"'<)
@r8345
GCGAGAATTAACCGTGGTGAGGCNATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAANTCAAAGCTAA
+
A?4C$1CE/?#8H!+H1-9106;9146>=%'G+E+94HC-530/$HF=3,G'$-!:#06:$)C),&%#2/F7F7./55;(=:'%5'/3-D,5BA%?>DADC9?".A"3(.;H;=!<
@r8346
GGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAACGCG
+
@G9-CD,;H-.'$AH<5&&<F09"FB6,(/:(5/>),:F6($@54;+$0::?=2*<E/11E2D6#?:'
@r8347
TGGTTAAGGCGGNGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCANAGTGNGGCGCGTTTCTCCTNTGCNTCCGGAGTGGAGGTGGACAAGGTCGNTGAAGCCTTCGGGAAGCTGGCCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTNCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGAT
+
+'+&'('+$(%$+*($(+!'!$*(&+!#(!*+'+%')*#)(((&'&)&#&))'+!&+*)$&"'"#$'#!##+%%!%(!'(!"(*%'$+!*#'+(!&%*')!'"%&+('#!&%#%(*'#("!##&+$!(!(+#)!!'!$$$"$$"%$*%+%+%+("#'(('*+&+++')%%+#*+&#%(*"""+*$%&&&""&'%+&)*!((*)"&#)!'*%%$+"+%'''%*&'$%+%()!)$+'+$&'%%#)'++#$("!''!$&!)#''+"$%%+)#*"'
@r8348
TAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAA
+
9BG"3;!2/?(6B@+4F?)DHDG5=8)83#E&/@ED!;E34!(=9+G"F'8.G8392FB>;
@r8349
CCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTG
+
$(C&0&1@42*20:7.67+(/3='<H1/)!46E70>&'29707758:/&='9,8:(;C5.B76D04'%5E*>&&)0!+&C(GE>G89C="-&!,9"3=0-1)%*",C;999F:=?
@r8350
AACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCT
+
<,7=;=H!$:FB:-F35%#5F/1@>E;331,C952$1C''!D!EEE4
@r8351
CCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGAACTTCGGCTGGAAA
+
F6)G+'9F'&+*,>8!1:<%9'42G)07;'%,B#8#D#F1=//"87:8*D98(99;H3/G-=;'G5FF':#9=#H>5#"H*BH%6G'5BD@
@r8352
GAAGCTGCCGACGCTNCGCCAGCGACTGTTCCGCTGCGTGTGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACNGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGC
+
F7,!'@*+'72C!E493><79A*:5&0%-*E$>('D15/8A195-:4.2=",,0"C"78,C(9=71#-F/0%7&7(+),76%0=C,/2D*+%5!$E0-'6!+#/FG147)?6%)4F.E5C/-9-B%8#)24)"E-?B3%BA06#9A+44));&,-EDH@?)@@*!04-/(6<CG2$H4?-F,F%<DH&,%#$CF4
@r8353
TGGAAAGCGAGATGGGGAGACAGGGCTGNATGATAAATGTCGTTAGTTTCTCCGGTGNCAG
+
;5&EA0;A4@&3E4F-AE;>6<?8,2!->#&!&2+!,G'6A*(?(#3/E0)1A5?D>F!>C
@r8354
AACGTACTGCGATAATAAGTGGTGGTATCCAGAANTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTAATGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATT
+
47;7&&B<*2<8;+!D>)@":6)FC7(03)("AHH&D--(@3#83+?4>+".+F%182E?0H$#,<(9&EGF)-5$*#'5;3HG;7%!A37?3/0EFF@6/=5'8<,3A4!4*(?H7#01/-31*A6,#54=8F=;C5:%=7.'E17E#C45B#,(@7;5BB<"&@+!5F1A/;?CC$!F.&AB>-:7C)7#9F#/%A+.3D"CE>*'!,,%=(:-@H!H$F94)6H*5620B,)<,:-25$8!.!2*70FG)#">H%B6'E(*A@HG3F1@F$D,',D13;684%"?$G.!,)-/128).7!?HF7765(:?7+-(++1%+=>B2/'357'=H71%/5-H@%*)A"CG-$G)(B6/5#'00=,6)-+1%*%D6(G66;=;H657F
@r8355
GTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTCGCTGGAG
+
B;8=%"*?G+G$<!-*<0=;.BB+E!/$(.1+CD7EF4:#'C2%?6$>GE=,;2F#1//,@&H=.,F(F/+E956&
@r8356
GAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAG
+
7='2F/<1-10.@H%&G-F-?2"=);=,(6H'B;%21390=(BCG5/%#"7(-7(4):3C<:(40<A))F#D.F8:A2**@+9<!F*F)&D
@r8357
TNNCGCCAGNATNNCNGCAGATACGGGATATCGACATTTCNTCACCATTCCGGCGGGTATAGGNTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATNATAATCTGCCGGTCANTCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCANAC
+
*'""&")'#!#$!%*%+)!+')'#!!'"&(#%#%*#"%#(&%$*$*"(%'&"%*+&#)$($&*'$%'*%'"+#(&!&"!$)*(#+()'#(&($%)"+$&$$*#%'"*&$$'#$)%"$+'")#'%')!")(+'#$"(+!++"%&''!$%($#"&!""+!#&%'"(&$(&')+"*!$
@r8358
CGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCNCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGGGAGCCATCGCCGTCAGCCCCGACGTCGG
+
+D$5F;7@#D-!8(0/<F31D!&G3F=5+,:AE@/7B:)>F<29<1#5+E'@F4B.<>6/E*?=*'98<-8H2'""H!%8=1#@CH>%$;?<0+7!C)F'F82D!!%&8+H++8)2$G1G!#265!*+.<8/<.C1E7./%;BEG.A<G.65B5;
@r8359
CCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGA
+
,.9*B0=@.338.?E.>75@5#%B!3('H(AF=0*878(2C7A9(+G(0">.DE/!BD&*?>3%*.4#)
@r8360
GGATATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCCCANAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGNCCCCACG
+
)+%#("(**&""$"+%"+'"%$$'"&"'&$"(()!*#'"*(!%&''!""$)'*#''#)!$!$'!!(##$$&'")(%"*$+!$$#*#&))%%#!%#$$'!''*"(&+'$#+"#$$#$%%$(#+'+"$#&'*("%*'*++#%''%&%$'")%#'%!+"%#!#$'*(+)(&$$
@r8361
GGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCNGNATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCC
+
!1H9F5?&1##-+B=E'26?5+&;(1F6,E><B:G&/*"038E*@E(A3$'%>-EFDE8HG/5*HF(6!/1#9=44>,=H56,&%?C2A.=-.99)=$3=1'0?*D;+2H)'.F(;;(=
@r8362
TTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTG
+
$:)*>0&1.6:8-&#:7B?724%:GG(+697&-H98&#895@DHC4@*"/*8,9(!H!D
@r8363
TGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTA
+
-,:'?%G(3@8.!'",+@#!(;":"16AF-A6G$2??7H6=(F-0!,.1!8#8.F0:C';;:)F#+@5!4!!EHG"=G396>4GC;2E8=+4>%>*EH/GG<"
@r8364
TCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCACGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAA
+
E!2-$D(60$*0-"E!FG7D:G9<8'#2/,!-9H28;9G<8@()?;!CBH$5-C1F7&C%B%G:01<7+<8-B$+C3==-1;@%F<248!>2($=3:65=('&+:G$*7*H!E"?7%B
@r8365
GATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCT
+
.'4'7<)-1<:'1-.'>*0;:!(+3F=FF<B@(,$,FB7=:2&19C)1*7D=8A@F1)EGC+&)EGEBC*5H&C7
@r8366
ACTGCCCCNTCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTGTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCAC
+
H=AB4<A5!(7F/G,)<+HC?D;GB0!D,36AH&0%0B8'58.B=%"5%>%>&@94)<H8+H2<4$EF!1GB<.%/@,D?/-&D@-((/<8"DGE$,7%#-3$<"(B(6)#9%#F9.>6=>60A-3@*-<@&';!AB<7&;'A@;'02,=#0
@r8367
CTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATNGTGCCTGTCTTTTAACCACATC
+
G@$3#F@&<A=@@G;#5E'0C:C9"'C7G#'$;#,?D&D(#)(/G+A'641C7>/!>A&$?0!A7%
@r8368
TATTGATTTCTACCATCTTCTACTCCGGCTTTTNTAGCTGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATG
+
D.6&3$.+37"2.?&G7>HB>(%AC;49AC3A6%A#$-*;!(=,2'035#,E&('-)A?6!%4DB<C>2#%27.'D63&&/
@r8369
GAAAAAGGTGAGCCGGTCACCTGGCNGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGNTTTGAACTG
+
+*')))""$#($+%$#(%)&+)!#(%%!%%)*&*##%%+!%$!%&'"$+%*)%&"$&%#+"+*+&&''*!%$(+)
@r8370
TCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCT
+
60"0?5@=C68,/*C$?+6#*&D)1C$6-,9C3/C.2A/(F>
@r8371
CCCCCGGNNNANCCGGCNNAANNCTAACNNAANNCCGNACGNAGAGGG
+
"!"!$#$#"!#$$#!""!!""!"#$$#$#"#""##$""$!"$#$$!$!
@r8372
NNCTCCNNNGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACANCCG
+
!&)%(#&#!+!(#$*%&!%+%+$!!#+'))!$(")((+&*)"$&!'$)+$*+(&+")!%$'%$$##(#+)&%"+(#&%#$*%(&&%&&+'"*"#+"++"+&%"*#*)%!"%&&$%+"%'%*)"+*$%)&(!)$*')!$())'(%&#&)&"*%)%)!'%&!%$**"%+%"'%*!$%%(%#""("!+)+)
@r8373
CGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGNTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAA
+
98:8;6-,A)&8';-!E19AC=<5;%4G?F6#'6"1/AB)A#:(,B&09$#-.)%5:,E8F,542AH/<!<".-'H*/D89!(+EA7=?/!AF<>!7@!,7B
@r8374
CNNTGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAGGTTTGNTCC
+
&&$+*##")$%&$"*"%$!&*'#+'%(%$(!'#++!'*(%%!+'#+#%!'%&%)$+&"
@r8375
TGTGCACCGGCACNCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTG
+
+DCD+D1F-(=$==G#E-98(%0B:HD2<32%E8/552"1"#6<E<,!HA'E*97A7?+,-@&<#&5H%E=/=GG=D0>:9<318D4>34C2-<&%B&)>E5$#HHEG2?@F;((=499HH
@r8376
CGTATTTTCTGACCGTACCGCNACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATG
+
A3'H)9"+'>&7349)0/>@G$#G'59>+#&;*$?#-B(=7"-?D3;#1,;D;424;3?C+,(D*G
@r8377
GTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAA
+
E9$$HE7D"E606E($,.?<G;/7<03++G.A)A"(CG:019F;>'12&67HG(80E?#H;C,0=F&C"'=E(0<)#,&6
@r8378
TTCCGCCATCNTCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCNGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCANTCCGGACACACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACNTATCACCGCACCTGACTGCTCACCGGATGNAATGGTGNCTGACGT
+
(@/3$@.+@C)1"@&%>4'(8:,E:0%*3F3E>8F=;C.C2-$21$A?G.6F;A,+C>(<%@H$"?5#8A5-=53*4>7F/#:C0;B%&"GH0;%6C/-%9BH.*3G%79,"3G<>4-35E6?7$597E11+:>)5>1;9@=HE6)6=%'3'@8B%6+D@&08$&<F?(%2,HAF*E=GF#5E*"%)+G1-7"&-969'8'2)/!CE#5D81-A."212,A*;07!
@r8379
ACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTC
+
'++#)($%(($*#!'"'%%+))%'($%(%*&$#&"%)$%#*"+*)*$%$*(&#*""#+&!$$+*+*&&%*!+*#%)&"'#%$#)+&$(#'*!#&*))%%+'''#%**!&$*!#&()(&&*($'()#*!#%'+"+#%*$$'!!$&$'
@r8380
GTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCATCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGNACGACCNTGAAATCACGCTGCCATCCTCCGGTACCGNGCTGATAAGC
+
;4!*$4)5C"A91.D/$9((#65:?5C&G0CC=$<2&52;A3"6=B+;BH?%-.D&8>75++:B74?H(<"E(/7F'"".+3!B+3##=.->/G!1:=5#C.)27+)@,!&@(C<(!(1.8(%$!##>#-@.@2F:#48&?17!=!E@5$'4E8B,>)-076169F,:'%CGBE43G/((-FC
@r8381
CGATCAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAA
+
:"7/*&G=G;527H;HE73GC9;>&%:8"$D%4?A#)&=(
@r8382
AATCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCA
+
>)+)+E6&-@F0A?D#/E"7(%A9),'5D87C24%2C;>C)/0(1;4*2(>/H(-";%+4,*/"B9%B.'46(@FF62',D!9!62@,,;(
@r8383
GGCACNCACTGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGG
+
A;++?.&E5CE()BC*FH%97&C'",-7B5G$4:-!=D&$+?*(=G6'44$9&0=5%%AG#!&G?8(%$9C3.7=!F:2&/@3>5!.0&6<!-:4=>+B!!A8E11GDF4&3;'(-:0.
@r8384
AACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTNGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACNATGGCGTGCATTTTCCCGTCTTTATCATCAACGAATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATT
+
B,9:(@FA3(B)='&$-3!@%&+AC3C)";,'C;//&+7#!HBAH6)()@H)A&:GC&0,2D:0,?*B5&-+E.D;12B##<D4$A/5.)7#5@3).1/.5==/%%$**-A%')H%:#B!;'4-*3&@<(.8G9,5.;?(>39;C>B0-%91D55+#HB!(B*G?2-<.2!.?+C3-D68$.1'4A%0@067+*"3CGB3;"G3>)/.>/?G:@;G)H/.%=H:;"@%)*'G,38/)H5":<B22E>>:0:8D(HF<@H!6#9?<<.)7F297A'*9"<#?*B'F,F,)CF<E5AH:/-D7B*3E;E
@r8385
GGCGATCTNCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCNGAGGGGG
+
%$(&%&'(")++(+"'%&$$"&'&%#"'&!(#++!#+!++&)!'+*+"%+')!"
@r8386
TCTTCATTGTACTTTACCTTCATCTCTGATCATTATCATCGCTTTTAAAACGGTTCGACCTTC
+
"#()(+$$&$""'((!$+()$!+"!&(!#(()&*"#"+!'#("&!&++!&++&+$$'($+%!(
@r8387
ATCCAGCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGANTGGGGATTGGTCTTCATTAGACTTATAATCCTTCATGGAATATTTGTATGCCGACTCTATATCTANACCTTCATCTACATAAACACCTNCGTGATGTATGCATGGAGACAAGACACCG
+
*&#)#%+&$#+''$+#&##!)!#*&()$''$()!"%(&+%++$"('$*!'#%"+($##!#%#$$#$%%%*+&!)'$*)!#&)"""'("%$*('$'+%'"&!#"$"(+"#"()($%*)!&**"!))#$$*#*'**!#"'*(&$")&!"%#&+!"%!%%"$'()!#!!)#$!'(+&##**$
@r8388
NGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCAC
+
+%)$+&%()*%'&)&$#%#&%+&$)'"'&#*&(*$*'$++(*"$+#!&!''!)!&'#''"(+%#"+"$!&&")&&%#+'*%"("($!)*#$)(%"&!
@r8389
NTNNNNCNCANCCNTCNGCGTNNCNNNNCCGCTNGGGTCNNANAATANNCC
+
###"!##""!!"$$"$"##"#"#$"#"!#"$"!""##!""!$!$$"$"$$#
@r8390
GCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTAC
+
E@/''0))1)H<09//9!4#+'H6#2&&"E,1,*8!*,'/(4%+4=>/DF5)5D*+-,6"0&!"131F$&=*34*(3DAE53G
@r8391
TCTNCNTNTNTCANANTNTCNTCAANTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACTCCAAGCGATTCATCCCTATATCGACNAGGACATTTTTTTTCGTGAGCAATGGGTATATGAAAATTGCGTTTCCGGAACTCCGGNTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTA
+
*%*!&!'''!'$&!#!%%(((%$#*&+#(&'**+($!('!&(+#+)&#')%&$$!)$#%"+$!+**'!*!'")$#+*+"%$'!++((#$'")#$#("'"!%"%&"$#%))(&"$"%*&'%#&('()("!"*%%%##!'%%"#!*#'(*$*#)$"&("!"''#!$!&$&%("'!*!""'("'("&)")')*()%"&!$)$#('"%**)#)++&!))&()$+)+$&$')$'$%##%)+$!(""**&("&$(&(&"!%!)"")!)'$+("+)*+&#$+&+)#)"$$!$)&)''!'*+&)+
@r8392
GGCTGTCGCCNGACACCGCATCCGTCAGGCTGCTGATCCCAAGCT
+
F30$$)6:+:)A;$BC9>480B?*BG=+3!@*0*,*2$/9*6G+C
@r8393
TCGTCCCCNTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTGCGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTT
+
5:+)4#%9"+4@<0@&6$!+?6,4;2=1?A5AC#FEF%/G9(62%+3&>0$F@++8.3)'"/9F/(;.))6*'?96G/=FG*(D.5A.46@8G>-!19.&;<ED"D.+-+H9C%150B>B1B3<D.H<6B03.H08*@A4*FB7&8"7'73@$$"=;#5=+F9!;7B)E6)2H#8,B1)(0?E723=./A5:9G:"CCE)@7+5D@0@@6'/-4=CG;F6+7,GE<'2+&2=;.?0&&#F+1C6F(5653%>C0H@(;F%H4*#$B8'8!;,<(GDG2B#7%85&0&";>,$A191C/@E
@r8394
TCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCA
+
:B'?4G7@6*21FF>4/%A/G6G*@9815+B;,91<2,4;;;($)1)>3.,E&
@r8395
AGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCANGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTT
+
(>0F>H=)3(@>5$=F=A6+#+:#H*#,*D6(;6-B$C6;A.$G-%+G%.,>>,/!B2@<0=0/(H2$7#&(E-)=7"B!%(C5.)81$-5+D*@+3,)";-8"#F!C(0=-<#DC@'3D*E='C%.H-$1$GB!9&**99FCG0;/B!!
@r8396
NGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGANAACGATCATATACCATGGTTCTCTCCAGAGGTTCATTACTGAANACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTG
+
):<#:4-)'>:)B1=;EA-%A5/EAAB/<.F#(,$$HGD/;;B-6(F9F40-'CFF2C;EF@H)+*6?*A$'=0.5E$9%#0:FB!?3#;%46%7$F"-B,+EC,2C%+GC2F*C4/<4<?G!=;+''(E$&*:529&7E4.,8,"AA=/6?24,#!HA@46GFB4*&G+$?#A$;EE90;E*E2%
@r8397
CTGCGCGACGTTCGCGGNGGCGTGTTTGTGCATCCATNTGGATTCTCC
+
("+%"$**$"((#+*''"(&"$$!&!+$)')%++&($##%#"%+'$+'
@r8398
CCGTATTCGATAAATAAGCAATACCCTGNGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCANACTGACTCCAGCG
+
#8599G&0@35@1;B-&;9,)%5=/3$:.+8@5C0-(((D1(<?443*"--BF/:*52:7&&"1H274"18:0%,%?2,)5A>#5E4-@C8D29
@r8399
ATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGA
+
4B/%>)G99:*/H25#$0<:C?B9792'H!>"E!)!H<(56-##8#+A!/,!H77C!*<.711C6&F;!77H5;0@D7G'$-2,5C1)F7!D*)A1#&<$<:;,E=!6BHCCAB#)<%.2:86=%2E!G85&-07+:)GBG2.*G:D?$F<!&883E,&7!)"2'50E:92;.48$
@r8400
ATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTNGCAAACCGG
+
12"!F->H"C!561++E15-'8+E)?;H>5!(B+==8C;;,&*';.6H*8<9#>";F*)AC$;@!4?F080E,G:63"$'*7<F8:@*3++.&B;@?<C);EGA"0)/-C6$$@8G*772?.
@r8401
AATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGNGCCTGTGCACTCTGTGGT
+
=?*BG)*DHG1G',1:G6FGF/9==4#B13#")2;G.-D+/*;C,(@=@0"70=,F=$'0635;<;;A44/GA!/6+.950G(6H?"C?6A*-'C?&!1+,3,+3%,
@r8402
GCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTA
+
=:@F52/6++))2B<B@1!=A#B/#4:%92!&<#F#9!4E'(B!)/#%,.0-3B431$E9<9G%.0A"F2G-H$6,
@r8403
CTGGTACATGGTTGAAACCATTGNTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGC
+
&*(+*)$()$'$**')%''!&(!%%$#)*))$'""+$+&+)(%#'))$%++*$((*&%'!$%!(&!!("'&+'%"+'&*)
@r8404
NTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGA
+
!13&$?)A<)-+?))>1?%9+A4@!E952&2/,@*?@8$'F(*
@r8405
CACTTCAGTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTA
+
+2!1%4*,#5)$#DF6!7A1&5)6>B!E>1#84)F;-2*,(=,
@r8406
AAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGCCACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGNAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGT
+
>"58&&17.8$2G64&&92'.?(!47.,5'HC?<G-3A9=;BA!@#H+E=E<'FC?#4B:)88.B%HE)/?=+5'1.1<%:(/<60"H/''?E)-B&F9"/@2$;G%>/F-G)>A&A#,,9&<H$"74G7?C"5=4<>?=
@r8407
GTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTT
+
:D4'?,:.@&%7'$G,7&:$E?9B#'F"#A$-:H-88&G;DC.2F
@r8408
GTAAACAGAACACCTATTTCTCCTCACTGGATAACANGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGG
+
FD>79=&,0/64??'7900C)5&#24-47#;',:1C&B?09DF'7G:;;1?/1':5;%@B@300><(!H>9-=2
@r8409
AATACCTNGGATCCACGCCGGCCGGTGAGAATTCGGCCTTTCCGGCATTCACAGTCTAAATCTTTTCGC
+
,'(1.ACFG7)=H:'8#>B8&?4=<-E/;$#(54;1'$!C1&%?6F2=$%41?7()6#2?!-057C9!?
@r8410
AGCCGGACCTANCTGCCCGTTCGTGCCGTCGTTGCTANTCACCACATGGT
+
+)*-+6"8;)8+&6-0".$*?,B)+CE,2(8H$&'(G"6.7'8.;9>B#*
@r8411
ATCCTCGNCGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCNCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTG
+
&#$&)%$+'"*("+)#*##$+$$%&"(!%%"+%(+*!!)'!'$##$)#"#'&*%&!(&!'#$!(*+(#)&&+$('"*%##(#)%!'*'&!&%(!&)*&"%#%*$""""#*!%*+*'!$!&))+*"#)")#$&"%'%'#("*)"$%*"'"$&#%*+#*!*#"$(&+('""$()""!')!#+&!#&*!"&$"$)+))"!(()&+"%'*$($#'&"!&$"&"")#(*+!)('!''&$*+$))&&!)"!*&+'+$'*'
@r8412
NANTCATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTC
+
'$$!%)##$*+&"')$&!)++!'!#'!+$*$%)&&$"'!"#'!"'('(&+)*!$+#+%'))'$'%"+%#$'+)#"#)%)##($
@r8413
TCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTT
+
7B4?D9+$--+<!%8:3$6;"G.:+33@";?;#$(C84?DB&$.B6?0F:>D@H3$(#
@r8414
NACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAACCTTTATGAAAATAATCTCCGAGATAAAAAN
+
#2()'G-$%=/'3BE23:6??4/!D-5/::69+D.D26>30>>,+@:)8(.AD%E:=,(G/BC6;E=BG/<(7G%<
@r8415
GGCGCTTACTACCGATTCCGCCTAGTTGGTCACNTCGACGTATCGTCTGGAACTCCAACCATCGC
+
702$!(D6=9%,;(C89=569G;2-)"=<<40*BA@0%6C"28H@&1EH+1A(@(;F&E&0(&DC
@r8416
GCNTTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGNGGGTTGGCATAATGCAATACGTGTACGCGCTCATCCCTGT
+
*+4E8!/:;H+&'$9<2;+7*+AA6E*'#49A92+>?C=4;:GH<G:6DA40(#B**A:6894%88-E8.:36.1$:(C)$CE,-@1:A&(&,=*DD3)F@/?D&/6+%.9
@r8417
ATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCATCCGGCCGAGTCNGNTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCANCCACCGGACCTNCAATCGGCCC
+
;;A",;0/?F7/A?D0?%0:;;E%*5#1F1.*G*@@,,&F0C!2!><%1)H"'&>6H$1?H&!*-C'6G0553+A9;.+$49>180&(99)EG7$4F4FB5;:3,)32">.=#:=5!A(G85%/%;GF;'#<!!*>G*18)$=9=FA3&.#8-:#/*.B7<("E5B7F$D'"&4&1($3GAF7,A%H($'CH1B?)&'F.=6A&<(<(9>H/6>8
@r8418
TGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCC
+
B,$A++2:C!A8*1+>*)!7AEF<"@C+")EA8,@.B(?<..@&;!4
@r8419
GTTGTTTACCCGCAAGCNCGTTAGTCATGGTGGTACCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCA
+
(&?6($EF,-?2A':/=H?)-@6'5&1"D4+=+E;FCE<6%624)'9"4&*==,/:"&!H2%;.6C>$.<:.27+%-(
@r8420
ATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCT
+
4/0=,>=D?$A8HH'.9.F,CDCF&/D>.A1887"40=;,B%AEG:G<41CD,8E
@r8421
TGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGNTGTTATTGAAANCTGCGATGATGACTATGCC
+
-G=5)0>(039G;5=:-31-'-/@2@0E*2HE>E#?8/?$/7G-4#;()9+E@7A,F=EG.B%7DD2:!8:5F7!=G,6H/?:=,0B9G!?F?F1%604'>/,=+=G(D63C8G"**8?,<%ED:!C1;BE?3#0H:4+D<6!0F:C5(A#<3#
@r8422
CANGCNCGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGNGGCGAACCCCAGGNAAGCCATCACCCCC
+
)(!%*+#()'+'+)%#*&%"*&)*)%+()%%%#!"")(&+*%"(*"$!(!#$%'"!'%"&%()$'$!#(%&!%$!+#($%)*+"##&)**+
@r8423
ATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTC
+
98D<17;%<B'//$;3"&>E32E:3--<57=-!"'G9?=H81C=(.H77G53<-B)$4#
@r8424
CAATACNTCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTCC
+
6%)*A;7%$;C9CG1E0H4-#$/1"$&!CD$#7+'5CB>4H90#GB62,("6@%;C.G??0
@r8425
ATATAGTAACCCTTAATTTTATTAAAATAACCNCAATTTATTTGGCGGCAACACAGGATCTCTCTGTTAAGTTACTCTCTATTACA
+
?A>D22+5'$16GC8=9?@>-?7'8F/=92#8$E>??G8&/4BB8@8&C22674>2#)H)?$>A"8BC+8*=+1.F5#547H%G+>
@r8426
GCCTGGANGAAGTATCGGGTGTTGCTGAACNGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCNGTTATGGAGTNATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTT
+
3'>G.&)"64FG;F+"HB81&4E602:,?8>AE7>>(D"+'%'4.(9/>G&A"("?H4G45%1+%,'$/622>2;+'02+4A%/==;;6#0HG;E#G6?EA+4(+%@%?$48F9,C7@=3D+*'/&/=*:)')
@r8427
NGNNCNNNNNGGCCAGCNCGAACCTCTTAAGNAACCAGAANANTACNNGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCNGCGCTGGGATATTACGTCAGCGAGGACGNGTATCCTGGCTGGAT
+
"*%**!$"#'*'!'*($')(&*"*#%#%!)%")%**!'%#"%%'&(!!&+&&*++)'$#($!'())(#"))&#$+**#$()'"'""*#%'(#(&++)%&"+"!++&#%#$+!#+)'%**')$%%$)%"!)&#*%)((#*&)(
@r8428
CCGTGCGTTTGATGACGATGTTGAGTTTNAGGAGCGCATGGCAGANCACATCCAT
+
+.&6=)$A*'-A$(F##EH*@+&9/G&GH/1#/8"H8C-/9%AE'CF58H$+6/6
@r8429
CCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATA
+
<79026GE6.-64+0008<"5)D$6H,7.#7155&"#1=7B$!#A!#H:)/E;$950GB,,$
@r8430
ACACGGGGATCATCCCGCCGAAGGAGTCCGTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAA
+
B)08F2G><9>E""3H3#997F1)+-)?"7FG!"6/<&-B#C)/<5/4*B5:;%C3:#/A10.@F3<:);,:'./8+-632E=(":B<D";<7"4+=E,7#/)0,A
@r8431
GTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACNTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATA
+
5D+)7%;)+!#$(<2,9'A(*;.5;,?@4&>=437@<9@(C%F>/?,3+(0)==A1#6$H3A!#7'/;A0'?$=1<3-$=B7#=;H:3(H7/=HH&)5.!H'%H>$G6"C'*,=7*3);'7"A=0:
@r8432
ATATCAAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCTAGT
+
>$A58C'$9,G@/,B=:GD$AA68F""7/1:9)3:/H.2;+0"99?"%,5B#
@r8433
AGACGCTCTTTAATATCTTCAGGAATTATTNTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTA
+
H:C(FE/''1<#D5%%7E--9:&)<7BA)CF0%-'"0*',*GHF-H).%'F&(4&@".91-+%<,9<*>=+*($:&HDDA&=%7#
@r8434
NCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGC
+
*?)&.?1<+7?8C(-@!44D2+,=?,*<E#03%9-"GFB6=<"?A07B.;G>=7>!F/->&+%!?&.<CG=
@r8435
TACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAGCTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACGGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTANGTAACTAGATAAGAGGAATCGATT
+
%+)$&&*&!%$!**&#)++$%+)%'''#'#$$%$*!''"#+)&&(+&#!!#&*")''!*!''(+#'!((&)"+"%'&+#$&'"%+#&#('$#")%"#$$)$')$#$*%"*#!$+%#"!*+*)(#"(#"'%&&!&)!%%"+#+'#'#')"!"&'(&#!!&*#+))*"(*'&#$%'&(%)!!'%))'$""#&))"!!%+)$+#
@r8436
AGCACCTCNTTACCCTTGCCACCGCCTCGCAGAACGGGCATCCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAANTGTCAGCCAG
+
+(?,5G;FC-=C'D>6E(>+(02D?)H&-D'8=56:*?FF/1(+'CH)%%;-4$7+8977DF./BA<GB,3:*G/!?#=DF?A$!5:68@F2D?&A1%
@r8437
AATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCANATTGAAACGATAAAAACGATAATGGAAACTACGCNCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAG
+
)B!)F//2$9#)%23?,$7+&3&,%6D8@6(2/*'A&%9GD9,9/-9766FEC$:*=&(%C-/F)!>.9&5/(5C&%(5@*1D5?(!<7+?,9D61D!'<C/2/$@FG++9H7F3<9+#;2&6DH7/C0?-/#)
@r8438
ANNAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATGAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGNTGACGCTCGACCGTGAAATCACGCTGC
+
)"#+%)#")&#")#!)#+)'%&!+#!*)*$'%&$)(!#(%$)&)&$++%(+##)!*'('!!&&#%#')$)'#)*%#*%*$&%$*&!##(%*!))#+*++&"(&#%##&%'(*"#''()*"#*+#(#"*!*'#("&#!%"%"+$'(+***+''*$"$'('&(!"+(!&#!%''$&+*"$!)(!%#""((%++!$"'(#"('(#$!"***+#%#+&!)&#*!$%(#**#(($($+#"&*(''*!%!#"(&+(
@r8439
AGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTT
+
=4'0H.=/64*:AE-#.*EGAB*(6G9G#,ED2+*;'6"4
@r8440
TGCTCTGAAGGCGGTGTATGACATNGACNGCAAGNGTGCCCGTGATGAAAT
+
*+BEH2;(F@7H6C,>#)))2H-9:*F9F@.>.'A-FG#14E,AD,A;#6G
@r8441
CCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTG
+
F;?>$!5FAG<B&74/>=%:'=EA%",B.-,<4ED>/A0<;4?H.&(3>E>C(>*8$67531.#-:2/.'$%)5.+!/!&E*>@7@D?C?2C5?@-+H!31:@:@&-30?C.#27'
@r8442
GCAGANCATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGGAATAGGTGTT
+
A(<F48;416;03@G*C,2B.*1"/C*16/%*:(4#&48GG2A@*!/=0&%6
@r8443
AATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGANTCTTCTTTGTGGC
+
?(,/50=1=E7*8-5>@:;4F/9#-(9H+);#5/?)A@>20;-@DEGA2;7E<"#!-'A$/$1
@r8444
ATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACA
+
46</5HE5/3F7H8,4?/DB14"=!.")<5,=,"!(,%)*/?<#5E&<D?C;D
@r8445
CCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTGCGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGC
+
=3H5B"BG(C=@$082=&61/F+E1)3:A)D.0!%.$>G;8*F,-<&64(3.9'>7891+9!7=:/7<0CA*0,+8"E98=H.%D=(.-G(4+(4F2'#5$G10H<7&<H@$9DE8-'B*D<98E%>C9GD0;:(9B4B1:4>0'D#<1/G?&="G=(.@&E.>E*-.7--<C(:*069939#??*6/4C?A.&-561&#'1=!>!!@3*<48H996B.!'HA4+C,9::%0=,H4,>2(:A81?H/:3/%F741G
@r8446
CCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTANCGTCACCGCCAGTTAATCCGGAGAGTCNGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGNCCTGCAGCGCATTGAGCATCTCGCCCTGATGNAANGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACT
+
B$(.9D0-!&A+F'636&F&!E#,2,;/?@(7/97-@4)4>&+A$<%#=%DG31:B<982<4CH'5>FB,+)#2),3E5EF>>)@41&G,/8/71(B=EH51+#/>86!<G:2D@<:.$9(")4@)=&-B.HD6%E$C@9C-2"-<>60<86.8#;?B!?:D*E:6D%E9+H!9%<B!,G21%0G"45(9&;@F@AB+8)+9H98&A$!5&E8=6#,7,AG:6E*4<D=#==@",C-(/G*1$6)C1/3#'E6!C#7>/7D*>/D05+6*B.+35&G<:(2/$2%4+,)96GE/"23""&3DC<.HF2A<7"=%6>5H19B;-9@1'<8F)##'9;2!%.>782E2?<=C%3H;<((E/$-":%H:G(",A/!A:0-,=/FD:,1+:;4C/3<A-&/;0
@r8447
CACCATATAGTAAATTAGTTACACAGGAAATTTTTAATGTTATTATTATCATTCATTATGTATTAAAATTAGAGTTGT
+
%AH@"94$;<2*/;H=GB-:/B<&%<>20>DF9&;)<">5A%$H@&F/@+5$/3:72F1,<E0C+@:8E!30F(+5"#
@r8448
TCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGC
+
62H.D4E?1$2G./1;D??#"25/=8A:%AH)A%!H72+F;*5BF1
@r8449
AGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAACACTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAATTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGAT
+
3EG198>;D=E#-,G/"/("+)5//,C1@)CG+@7:&,7H:'A(+30G@EAE+$C(;%!>)*356>8;5(<1H-!2>:;(C6)8=<#2B+::1#HFH1B?*G,B6!%4=E"G$E/H>1//7-DE.<36<-F2;6&+2>))*1D$<=5CF2;BCA
@r8450
GCGTTTCGTGTCTCTGCCGGTGTGGCANCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACNGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGA
+
A2#88'1HD%6<06:G#&#)0D!2;5$,!,A539,5@.B$@E6+3523,=6AA/<EA0D#HF>:7+:/@E(5B(/148<//190C+-63':0=@93@&B!;>;6D2<+*D6?/?56;F;%&6!E1(5
@r8451
NGNAGATNANANNGGAGNCTNNCTCNNNNNGNNNCNNAGNANGNTACCNNGNGNTGGTNTCNANNTAACTNNTNCCCNCAANNNNNGNNNNAGNNNANCNGATANNTNANNGCANNNTCNGNNNANNNNNNNNANGNTGTNGNGTGANGNN
+
"#!$#"$"#"#!"$#$$"$###$$$##!#"#"#!""$##$"##"#$#$#"##"$"$$$!#!##$#$!!$!!$#$#"#!$#$$!"!!$!#"!!#!"#$#$"#"#$!!!#$#$"!#""!$$"##""$""##!$!"$#"$$#$#"$$#""##"#
@r8452
GTACTGACCGTACTCCACATCCATGCTGTANCGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCA
+
&?3*--:C$D<!-3%G*9@5C&-8=-C!F>2/<5<"&A2C93;:)&"-%2/2;:EHE7;8E/!>AE80.+!3G>
@r8453
CGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGGAAA
+
7*/;.1%4706*#)!*-2B47@'$E6G(&-<:#%=C'.?<
@r8454
CTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTG
+
*'+)"!++$("*#(+"")!%!*'+!!!*((!''$'(#$!!*%"*)'"")*&+$)&))#*(%&$++(*$"'%$&#)$"(#
@r8455
NAGATGACAACTTCCGCCATCATCCGGCGAAACCCGNTCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTNTCATCNGCGCGGGCANTGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTNTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTA
+
!A:6:'>AB.?4+4<$+7E!7?"E,?>(%GF'&(<%A5@9951;4'#&F86;-&*1;6CA;:C1$1;*C4/@'>!?9($+&20&&@$.>E;+9B:'7'3)8!4.GD-$?A>/*=?H1;=%51:>.6@G9(>#<>,41>=$=@<EA;,)2>&7A33!)F+C#7:@0E37D2FC0BE"6-9C8&,5#B.;)-0!+2H;$1/?H&.,2D?0>,7G01=F;1-<#,5,.0&>/B&80<$,5!=C9;8"A0"?'.3#'C9)987>"ED+'>"B/#<<E7B%G3$$#A3;>D<%9'"$1D=?:$.@=3CC03-/+#>&7-?!>G#*+;/+B/:F9GH@!-'"@@=C&D35="$1+%--58"1$A>#*FEAA9.$1@03F'<3@.?%6;,*.F%&4BF<);&C'%6:4=!31;9(B$(9/#<C!$&97"!B:+))>#68A5+37EH(3B,!
@r8456
AGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGNATATACCGGCCT
+
9$E<4A;0F6,F=0)$':2A>=12:;2!+C,9C0#2''F$10.;"!113;49A!.E&==GG
@r8457
TCACCGCGATTATCTCCGCTCTGNTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGNGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGG
+
+#)(&'!*'&)%#!#$*%#+&*$*%(()*%+&+)!*%*)'#"&*+$+"%%+!)&$'+%($$&+(($#&+#*$*&"&$("(()%!*!#'*+!++&"$"*)'(%$)*+&&#"$'*'!+(&%!&!&(!%$!''#$!!%"")
@r8458
CCAGCNGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTNTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGAGGTGATG
+
-D#B6>G656F6$F.<)/8:&B,>02=-H8<"0DH$H!?!#H-793B;0=H,+6>-6.31'8"345!7);AFH317$1=*(&/B3A@,C%,"9&CC7>1"!!:A'75;D&;:FFB!($C*C'-AGG8!B0>:&(#=1HD"6>6.1BG..2166/!';0?BA)2>+,'?#;+;22,:B5&?75?:,"?5C-F:0A:E?FFC*H/B>H@2#(G9D>E!F2H>-D6?)7@/&-74F.>B;!")*"-+B,((
@r8459
CCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGAGACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCNGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCACGAACTGACTCTCCGCCTTCCACAA
+
#,B5GB%B,HD&A@<+@A48="6D#;AA8#G<@GG/7=7>B,+4#B$E&)=:;)0+(6(7,+$(!:8)4+#0G&42>B2;*9$>F7<>/$3B:B.6D?D)F>C).1*2!*6?.">'?EH(3&/('F1==4(A7$1!:->$,A"=@F#.2++A0G#!)%A;@+13;C<AC718#$+H527/(?(;5B-;&<,1>937!(45(B8B<#6E"-&#C36CG
@r8460
NNAANCNNNNATNNNNNCCCNCCTGNCNTCTNNCCCNNNNNTNGCCNNNNANNNNTNANNAGANNAAACCNGNGNAGNNNANNNCNTNANNTTTGCNTNNGACCNNNCCNAGNNCGNCGTNACNCCN
+
#!#"#!""!"#$#"$""##$!"!!#!!!"!#$!!"$#$!##$"$$$$!""$!!"$##$"!""!#"$#!"$"#"$$""!!##"!$""#"$!$$!#!$""#!$!!#$"!"$"!"$!#$""$#"""!$$"
@r8461
TCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTG
+
&%@,#!5,+2&C1F=@<FH2!;8<"%E7/&'#=#.=D:-:"69%*0EA3&HF8%7&3@.=37BH8B/D!
@r8462
TGTGTNCNTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCG
+
(&")**(+$("*'%'""!$(&%)$")#+('&'+(*""(!"()$')''#*(+&*'%*'+(''+%'##+(!(''++&%*("#%"$"#$!(+$&#'&
@r8463
TGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCAC
+
2><+9<8B,/!:*A:7=%).C?222B,B(&B!!8B?(0A1=@E=*?<H14@@9BC98!%:>,*6B,FFE?&1;"(E,6($#8G%!-@&%0!C5EC))(3+:&=%0DC*A!98;&F*@9B"D>5H(>AB*;.@HF6.B*:',E:::B=7,F-=$0@3"4>H9=+-<.79?)HG7:"(/8?A/#&@,&);3.+?G@#AG(9GAE2#>(-@
@r8464
TCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGT
+
9D+42/?BE)6"&57#-.$1F,G.<4597B-G.D7D>F$=C6A>9D",5(2,.!?%$"@0H%!7*.)?=*'*<&59'(6&H8:+4G9='0=1-*3:9(768D"B);=(4:*&4B18F22D&:$73<!5->B"(F;8:F!&.B>.,A('?"D@'D9'36;.E'5E-F($5:$&HE2$G5D%D06C
@r8465
TGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGAT
+
B6A&=+=*+(&=.&@71>99+3,+%%$@,<A49:6'7)=:10&1#?+
@r8466
AAAGGTGCGCTTTGGTGATGNCTATTCTCAGCGAGCGCCTG
+
H6!85H?'89'HC(4/@4D:@*3+/A;2G=!E&BA$:)$%G
@r8467
GTTTTATCCCTAAACGTCGTTTTAGGGNATTTTCCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGCCTTGCTGCTTGATAATANTCATTCTGACGAGTTCTAACTTGGCT
+
55G),B+(;E'-%@2!";9)3'*/EBC4-D2G1!(91+6!."D4742,27B'+;#;=5%@'(6'0GF=3-*B78%>:("6395G@09(G4%4,E1E%:HE<7,6/C:GE;1=</32E<"C3.5;.:8.>5)B=1
@r8468
GAAGACNGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGA
+
=+,=AD49?'76)>E-,1C%3E4EA#H8@B=.@59#0!)=EEHE=A=F613G@G@0)F0FF2,:5G:#;(>E->%37H'-($B<2625G5*'C+;6<FB?=?=9G41.4
@r8469
AGCTCAATCCNCGACGGTGCTGCCGGTGCGGCAATCCGGAAC
+
5D5&*1427GH*"@.*&/'G+-#F4=:814EE/8$-GH.>)9
@r8470
CAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTNC
+
()))+"*!!&!#$"+!!$(+(!$&+!&((!%&$&'#+((('('$+*"$#''#%"$+#"$"(&(*'++#&!'&%&')($"+$##%+')''(&)#!!##)!$(*%((&!+&"&&+)+&$&)*"$($(!&#(%$
@r8471
GTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCNAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGATAATGGCGGCCAACAGGTCATGTTTTTCTG
+
1;).7,A0$3*6H>='&C8B8F:A0>//5?#(H4%@":11F$%5<C5BH#CB#-$$);1+77@@9%!+E!HE655H/(/"<A)>>.D'G9<:5=2E'8A7$3-?>FA7,;(A1:1
@r8472
GCAGCAGCAGAGCGATACCGAAGCGTCACGGCTAAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGCCCG
+
729.@)E1FG61,B@*5.:$2."#'33E95>:9;G*0%42AE!A*G>3!7#"H!64,.96*&208<?/+":7G:9=A3=,-)C&G+%B1!AH0A?$<(.@;7C7.
@r8473
CTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCNAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATANCCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCNCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCT
+
E1*FF1-!3/>013!-'=F/B5-?;<6D?A1.!F:)669'<,<!<*?&,FG7,/H=(A"(FC)=8A8$&!9?&8.&'G)D&.H9&)=5H$A?G/+3A<C5,3F1,.+%/<"A0DAE9#/7B60H2%=>2&0F;>E/8)4D;+B2GA5;:$65)!>,B2731'9#E;<E8A5F(A7H3;0,1@>(;D910=>+$=G*0'$""0:EF.4
@r8474
CGACATCCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGG
+
<'C(,5-(:6(-/2)F3/'(%D>.>"@:16%9=?842'B<+2.#0,6&+4:#E$
@r8475
NNAATGAANAAAGACGTTAAACAGATTGAGCAGGAAGTGCTTACCACC
+
%##&*%)*!%'''")'!+)#!*')'+!&')('#'*%")%)'#$)#)"(
@r8476
NGTTTCNTGATGNCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGA
+
"#&&#!!$)!)'%+*++)&))%')+!(!#(%!!"*)((&'($&#$!*
@r8477
CGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTG
+
F1%<%$E.B6>!4F.6C/#C8#@DH8+43?/%;G?@GB9"61$!/4BEF&;?-
@r8478
AGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTC
+
$'+#)'$!)")*'#')%'!%!()!$'"&"'!)*)*(&+"!'
@r8479
CGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCNATTTTATTCAATAAGTCAATATCATGCCGTTAATATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTT
+
@9A5("&F>$G@-23A#?&B<5,=?)/G)&2!976"CF,/+E3B'@>E!A8.(8"G=@#$,-'2?"!826F&1ADG/'@G&:(+++;%E2F/1=)-=E&4E@E*:(1&13/DF4?5&=A0!3>5C<C0:0!/<#"E/%/
@r8480
GTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTT
+
2(4A85FC#D+D'-<=3)A4B2)$,(27@<0(.,GH$<-'GEG(D>F;*&4C:%!(.>%0+0B(H)4&F@$4
@r8481
AAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCGAATTGATTTAATCA
+
9<7%=:*$0?27:*7%1+9F)001'8GD,#20?#,#?7@'*>+2'.3B70/7+<B/85D(?*AG"&>EG2,H7=C>06;:B
@r8482
CATCGTCACAGCGCGNTATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGAC
+
857-.5C0C"F+&@BEE!5!:E;H"E"D36+6?@DA#355?H%@A>,#B$H!-:(?H)E<C>/@484&5!;//&"&5:00F
@r8483
GCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAAC
+
B')HE*:H-4?*$2+=)7=*96>H#61A6.:$%/CC2.G%(7G>FA(%F##!3/6CB)GA::+;&B/-/%,/07?H@?B)0%D9$%(-9,>-F+(;.384+><'>."*:;?6-CD#"15/<12@5'''68D00B8%H63@6,$H1?+',@:4&%D1#:A7=/60!718BG!5%A2*-@@56D9:A!?/'&F)#4!FC3&#0F(*A#BA>:
@r8484
TGCNTTTGTATGAATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTNTTTTGGCTCTGTCAGCTGCATAACGCCAAAANATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGNATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTA
+
"#$"$)(($&()!++#!%"""!#"#*'"$))$(#*#*)*&$+()((+(*+)*)$*$%&#%&(*&&"%$+$)!&&")$&&(*(+#%)$)%%&!"%)$)$#&)"$&%%&$'"+()'&)**&!&$((!$%!*!*##$%+%*!($#*)&*+'#&$'!)"#(*%(#*!+$'+#(%*++*!#)'($("'&$%*("+$+#(#&#*#*##')&#$""%(&+)"$)(!'+$!)
@r8485
TTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTNTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAA
+
-?6=21A=<64A<$")-,%>B++,%@G80271)1#!41#@HF9+F&112"*@3,2)0G11AFC?H#8>*E=?H/55'F/$CF%AGG<;0EE1.5A"&*F/@
@r8486
TCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGC
+
E3-:>44.A,!.(DH.)+1F#!!#,"AD4F02C9!0B8/35,
@r8487
GGNGCNATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAG
+
&'"&!")*!+#&+*%&$))#%'&&&"'%'$$(&'$$!%))$$*$(&%($!#$$))!
@r8488
CGCACAGCGCGAAGGCATTAACGCCTTACAAATAAAGAATCNAATGGGTGACGATGTGATTTCGCCA
+
3;)*:G@>-/,,AH%:&'-20:7*AE!96-&"&?3=@;4='@A8"(8%8D2("5@H(/E%-G&DAB(
@r8489
TACCGTCCAGCGACATTCTTCCTCGGTAGATAATCTCCTTTGG
+
&5%-)B#?A9A)6'<?42B$H%,A=)0;44;E!BH?EFE#110
@r8490
GNCTCATCATATCAAACCGGGCCATGATTATTACTTTTATATCCNCAGTGTGAACACCGTTGGCAAATCGGCATTCGTG
+
("%(#*$+$"%#!")(!!+&$*'#+*#+"*&#((($'+)#)!(*####%')%"&$+()"*&*''(!)'&)'(!+!!%+'
@r8491
CAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGTCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGATGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTG
+
6H<;2".F45<D<3(-A20=C2#H73EG/$2G,5&%??!!$#2:AFHA'9(=.EE+2)%A@<%H'G!-D2C/6!++BFD/"4A6->D&?G@&-)4C(B"B7(C,5>7*377%=@)-2,-'4:7-?G;+%.BG4F=(5G%=HFB'+;G#52)&G!H=&C,</>";8FF(<4+&-#58%>0$"/4)2+58.9.01$D-?&D$:C+&92E/HC
@r8492
GACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCC
+
B8&4:,#**C5-B0*D=D-D1D9D80;>*6*89$;2>8;%G&*!&ECF73C#.1C57@#&)0
@r8493
GTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATNGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAA
+
*679&=1&%@4':00=:F5E>*-@4G.@%8D=<55,1")5';&;".1!.'+=1%+@9++/-,6-%8H@-%HG<50:.<D*>$0"4?2".E'?3&0(@/6*.?H#:=>76?,6FC37*1599@=EC,+75E:=F0DG6A'/,B..%,10,=2H%=2!9(9!%7#ED6.G79(9C:>8;F*:A8A
@r8494
TGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGT
+
+$'$##%#+"+$)%#"+$*(+$%!$%'++)"!!(#&("+!""+))(+%&#%#!++)%+'!"!*'$#'*&""*+&+++"!#'*$$"#)+((%)**$&'!*')"%+"!#$$+#
@r8495
CAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGG
+
5/($F<E.0EC$':B1'=@C0C&:,,C-;%%=8G<?GB)29)55)
@r8496
ACATGGGAACGTCAGCCACCATTACATCNGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGAT
+
$+''')+##&$$$(#*('$#!$*''%!)"&(!"&*!"*$(!++'$#'&'%&+%"(&%+&#+)"($$*+
@r8497
CCGNACCGNNTACCCNCGCCTTACCCAGNGNGCTGTGTGACTCGCTG
+
'&*&)(&#""')$&*!'$')*'$#'*'#(')!')*(**+*!)&(+$!
@r8498
TACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGC
+
4/@*@&<#4H8/?8@==7*!B-;=8(>?;@G*A%&9@;)"):/6F
@r8499
TTCAATAAGTCAATATTATGCCGTTAATATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTNACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCANCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCC
+
D="200(,C;#A45:%ED=//3(9)&$A%2*CA!/"8=G:B'+);F<B!*'E$*>;95(,")G"/A>BB+F>7=D21:D$.14G<=-A7>114;&8!":/,42+5$<;'6#17!B,="*:*F%8A5!6-6&$F"!(7F83E!AG*)"G!*D22&E+>C187,D(C)D:(HA320*1!13E"DC=H'BE1)&.<+H"<2G9-(#%)H2.65?E@,>A
@r8500
TTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATC
+
2D("/H<!=%/+:$6>892?);/&,/-'7EHBG6+%,'>*18'03>EH8?@*<A+2!.
@r8501
CTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCAGAATTCTCTGACGAATAATCTTTTCTTTTTTCT
+
A"73:7(D?F-3)960>/A68,760@EF:==0D6,!07G=<F?A,@/7,E)@,*!A"=E>"><$!";''-'8-A.9/D*C"B?5D)D%/.4,@=>B9<E
@r8502
GAGAGCATCAATATCCAATGCTGTTGGGATGGCAATTTTNACGCCTGTTTTGCTTTGCTCGACATAA
+
'F;$0+HD#5E+6C9;#0@B1,'$4,3*E:5-F79.,"F<43$%+"*?A@4H%:&FDGC+$0C/7+F
@r8503
CTCTCGTCAGNTTGNATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGAGTTTACCGCAGNATTAAAGCAGCAGGATGTTGNTCCTAACCTTGCCGGGAATGGCT
+
'))+*&&!#)"")"&)(&'&%($$%(+'$#'$'"!("(%+%*+*+%*"*$)%)&!"%*#$#+"$%**#()&'&*(&+$))!!''"$!"&$()*+"&(!")"(!!$###!!!')
@r8504
CTCCAGTTCGCCGGGCATTCAAAATAAAAACTGACAGCACCC
+
+$')*)$)*(%**#!&+"!($'+*#"(+)(#&!*+$)!"#*$
@r8505
ACCGGATTTTGTAAAAACAGCCCTCCTCNTATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAA
+
BA.H@B":+4,@A*@EGE>./,60G?>1/C*?8:)3(4)1D2E3GB(/>:>H$F-?:&);F8%4:F*7"EC50)H$D?G:EB?5,7:(@->=C/?0C?-,?0+<HB
@r8506
CATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCNGCGCCAGCAGCGA
+
E02CF?/:F/?.<$+-DC:.+A*1-%F(H90A>2(4DB#2%G6??/#0B?#5'0D;=@@45#(+A;9!11*CE>.$
@r8507
GCCGTNCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGA
+
@03('0H:E7&>)4"G.H/('5@%2,03,3D91)#8C6-';-#=0!G6GA%()%>#+1#E2E
@r8508
TNCTGCAGCGTACCGGGATCNATGTGAGAGCTGTCGAACAGGGNGATGATGC
+
$#9*4<<"0'?2*E7#$-30G:.>7$A2)$-;5,'1.?74AG'=5=*A3/-<
@r8509
TATNCAGCTTCTCCNTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCT
+
@.B>"6F,B8"*@C-H;$84#>H>*0G!2,B):&G80*%C'0*(#0;5F3
@r8510
AACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGA
+
03<.(H<@G=%A&*>AB40,&ED9C,%*-G?<<G15>=A6!(C,H("%4B8<)E5$.+8+D"153=F$5
@r8511
TTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCNCAGTATCACCGCNAGT
+
@53E@(FH';#4,1)05<6'H!7@C5*>4"1>.0B-%#&66G>)0/0;B.1?"2>.8F.8<-8D
@r8512
GAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACT
+
H47?&&,?:F"2A994H>?F:H3321G1+418-6)H-%#2=/D8C;30>++.2**.A=")35>(D5;5!2@E>
@r8513
NCGCCCAGCCTTTCGGNTCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTTGA
+
0<%F0.F(81<F<&(;"+"<143'&8G5<*"B2(&#B6&;FC+33"-D-312?<8G$9>*?$A$)0+3C
@r8514
CCGTTAATATGCCATCCGTTGCAATCATGCTGCTAACGTGTGACCGCATT
+
5:/<17#GE8>:5%>349D1=C9H9F+3=E/@/B.*D?7,6%5;-!(=6)
@r8515
GGGGCTGTATGCANAAAGCATCTNCTGTTGAGTTAAGAACGA
+
+ED&/@&/"18/%5>;&)(%/0D<6.,6B(:E-G6-3:C+5&
@r8516
NCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAAC
+
">0=%1C2G@:3&?5%=%F"@*C>3165)<&=F?/2./H0!.:A:>"E:A90;9!;1F#0.'7?'07
@r8517
GCTGATGCTGCTGGTGTCCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTC
+
;1<*!9.3@>04%/3):F.=HA+5.6?1B%:*'-H-$(A"<H!:47'&4>;?/.:H-1H(+9;C)F$D,-&$0G?1/
@r8518
CGTTTCGTTGGAAGGTATTTNCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTATCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTNCTTTCACACCGGAGACA
+
;*4>!1;>584;:+!5=7"?D1"EB4F26,'7,?/4/80/!8#:.9+?A&2CEA&46CB@3E!:D=F*872F/::6(,8A3/-6ED/*,46%7B.6D?)%.@/(6G*,FHGD0FH61;9!)9C1<07>1:
@r8519
ACATGTCGGNTTTCCAGTTCCGGAAAACGCCGCTGCACCGACCGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGNATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCCTACTCAATAGTTCCTGGC
+
#32/A!H!5@+CE!/(,0#44=C7.,F+9%,A,A:#%#>A+/8%@84/8'G>=B887?H/>EH&71F%&+D>?#(')G.%A4:=0:&6%DD&H%5GD;,+6H*,H=:';!?@C1)@(G*D#2@40G>46%81++89;.'4!.):/G6%A<-7!-'6?H&?"D72!>17(/9;-?$.8>?30EH*:B6-)9'00H&F*4G8,D;H:EHH2"
@r8520
TACCAAATCNTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGAC
+
9+(/"=)%:(FB0.*E<7$#.$3:;=&/H7?%5A:821%",6<>937G=,A((#!1!--5%$5G899H,H+?H>%H';3>887C$*G)<=4+
@r8521
ACCNNCGNANNANNAGGNCGAGGGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGA
+
#"%%'$%#%%$&%""%(")("&"++$&&$'!*$*#$#++)"+*($)(#(&!+(!%$)"'&$+*)$+'+&$"!*(*)+($#!&&$!#!#+)!"&%$''%*(""*!+*&#$#)%%"'"(&'!$*
@r8522
NGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGA
+
(77>8!36>/6"1BH$0G2BG"+.)!)/=?,3;7!'D=+:8?87)"/5+9,0-18.9&0E(*!>@%>?6@BD@,0&##B2-7"0?C'"&;H7$",0
@r8523
ATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCC
+
2<=)7G$7?4=4?7AAA75&AF#;@>*8%?+8C5=A<8.,=8?,B9@3B8?.55$=>&G%676A>=@420%H'<D&&E)CB'-7
@r8524
GCGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCGTTGATGCCATTA
+
+$'#%"$*!&%!$()+$"**")#'(&("*(&+++($'##!$##&$!'")%"%&'!
@r8525
GGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAG
+
H.!6CH.((;B)(&&2&D<'F@&61!H/-<:H:@@=B7#<),,*F@5-C?E*)'C5,<F7D$2/./.4$0<&"
@r8526
NGANGCAAGCTGNAATCGGAATGCATGGTTAAGCCTGAAGAAATGNTTCCTGTNATGGAAGATGGGA
+
!))#"+*++#$#"*#!&!(!#(!&")!)&!'%")#)*$%!'+&+"#+#*&"(#("+"(+(%!!))+*
@r8527
TNANCNNNTTANCNNCANATCNTCTTTCTGATTTAATAATA
+
'!&'#"!#"%'%*!&(#$+$&)!)(%"+!#$$")('!($#%
@r8528
NANACNTTTTATATGAGGAGGGCTGTTTTTACAAAATCCNNTAGTAACTTGCTTACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTANAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCACTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGA
+
((%%'$+'**!*#(+%"%((*+$#&(#"!(#!+#!"+)+!"('!$"*#(&()#+*)!"%)()!!%'"!)!'$#&$")(&%""($#!($*!$+&#!)&+$*)%#+"!$$!(&)!*""&#!&('(%#%%+*((#$!%'#'"()%((%(('+!)!(++!*!++(#'"'"*'()))"($++&*(#'"(++#&+&*#""&#)")*$&"()!+%##+''#"!)+(&"'%'$
@r8529
ATGNACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAG
+
+.B*D;#(BB2;E(%.3!28A>>*DH>?0<"!:".-8;6C1-<6C,$>-*$#B57$0A,%F)"#9C%,64@4'?D!9-#$9A@H!-%BG>,8%DF.B6,0<D$/FA3C?+4!G:A1199))5%?7..:@
@r8530
GCGTCNNCGAATNGTTGCTGCGCTCGATGCAAAATACACNAANGAGTTAGCTGATGCTAAAGCTGAAAATNATGCTNTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCANTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCTGACACNGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATNTTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCG
+
%)'&&&'%*""!!+'%#$!)("$%$!'))(%%)#!!(**(%&&"")(%%'#!"#%&%'!+#'+"&!**+$)'))"(%')&+#*"*#+$*!)#%"!*#'('$'&)"!#(&!$+!#)(&"%&&$%"+%!'(!!*'&')"")&(!(#)#(%&!'*+"$"%(*#%"++$!+!*$+&&++!*##'%+%'()"#&&*"*'(#(+$!(%")%!)%")+)(&!&(')%&*($#"$(#'(%*)&#*")(#(!&'$*&*$'+(")*+!'#)'!&#'&+$(%*(&$(%')!(&("%'#$!)*!%)!'#&"%()"+)))&'&)#&#)$*"+!*!(*!!*!''!"(!!'')"$*#*$**#'&"&**%&+'#
@r8531
CCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGTGACCCTNACGCGAATCCGCTTTCA
+
=F!=%,:9''%%(,E2D*G0EE$36H.,:1=-4?5(>>-?1+(++@$"8".+GD!556-*4A>21!B""@07
@r8532
NAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAA
+
!GF-@@7-7#9+!3G<H9'=F4><08%BA!<,E#E?1+?H51?<
@r8533
TGNNAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGAAGCACCACAGAG
+
$(+#('%'!*%!$#"#&++((#)#'&&+#%%&$&)!(**#*&!*+*%"**+%()(#($#&"+)!
@r8534
CAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATC
+
G-A4&2:)2=7+1=")3H2H>9CE6G1G0=:=,<C$*%)&H54(,"%G9<50:*)
@r8535
AGNGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACAGGGTGGTC
+
$%"')>&H(;62H%!813C/F(5.,G*/$%B-5)!-78*%.8'$0@9$E67
@r8536
NGGNGANCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGT
+
#&&&$)%&*((&+"##"*(++#$*")'!#!)(!"'!"')"&"$"*)))'*&*
@r8537
GTTGTCCTTTCGCNCCGNAGGCGTCGTAAAAAGGGNCAGCGTTCATCC
+
@)A4':$7BF;;'+98=?-BA9DD(>%2+09C)A,A!G-.F?@HG49C
@r8538
GTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGT
+
G&F"52;E7"6</)7(/#6>2,:?<0G-/;(C4@93"@0:20A@,#,0.'BEF!EB!,03"*9(0>-@'%.F*A6*7C,%E,:)1;.,F>22(6
@r8539
CATACGGAAANCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAAGACGTTGGTGATAAANACGGGAAAATNCACGCCATCGTCAACGACGTTCTCATGGTTCATCGAG
+
3."#G*!.-3,/+AC@B=52<G)=;:G?GF??47(8=6(?H*F!*0019D'0G=>3'F1-3@4(.(H6*&&'GB4G'6)160;27F"%C>#.=3=1!.&<'4'-C%AC55)>4%+;/+(,A3G$)6
@r8540
ATNNNCCATCNCAGANAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGANGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACA
+
$*'$*('"*&""(%'+(()$)'()"+*&#+*+"!'"#(')#(!&(**#*$&#%+'#$&*(%$##+!#"(+"*+)$+()!$#!$*"*+%+!%$"*+(**&("+!+&&(!+'(#)##'*)')&+$)%*)$&")"(*+&*!#*&)"'"!$((#*))%!')(&+#))#!'%("$))('"!+)(&+")+%%#'+##((&+!"+''**&$"&&$'%!(#"!#&""
@r8541
GTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCG
+
&8:!&&"9*(<G0>$G+!-3/9$'/+7EC$G8*>=?9$")@?=G=!47@C/(D:.7E#$D@+G57/2#,(7CCE$4=E87'@;6D'9ED-07B9G3/&A(G)+(29"D.(=B&3#*6@>A?4$>F>G=>6?/#>F#8;=&;<49
@r8542
CCTTTTCAGCCTGGCCCTTTCCTTGACCAGTTTCCGGCGTACCTTTGTCTC
+
#)'+"*"'&(''!'!(#$$*#+$"%)!"*'%+#$!&!''+'&'#*%&'!#$
@r8543
NAANATNANTNNNTCTGNNNGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGA
+
&&'!)$(%*)!)$'&!*!*#'+$&+*++&'*+#!#')#&+&**++%+#(%''*')((!%"&()+%%&"#'''"*+%(+$#())&+!""!+!%!#*#)!&)+*$+&$
@r8544
CGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCNCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGG
+
BE;=;-C?!2959"D%*941*B4@F)=)=!>2/BB/HD5':;"6:G@5A8>DB76.=%1(?A&.;5C2#*?@+G/!B;,5)2-2A>6-5?#;<*#B;--@*C5=E).E&5&.%)7BC=%>-&4;=:42*B!:,-17-"G7%=7;:@"8@+D!-)F-.C,93;&F1(5@=&@/6971$1%8),G6#3&>.C;"=C
@r8545
ATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGANA
+
@4F%B5A$>1$.4B0)!6E"#*"6#-=&+.7*'6/>'--977A=&<:D)0EGB$4+'$B
@r8546
ACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGNTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGA
+
F'<HD;*><%%+,==AA9H&37;&C";*>'.8/>9471.<E=(:;3/#52()E7<=)9<EG4.@?(0>G.,48D112)6"?(#)7E(D4H:8C!%E"HF4G+!63))AC
@r8547
ATGTNTCNTTTNTACNNNNCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAG
+
''*#*&*$()%"#!'"($#++%'(&()!+")+*!"%""!$*'&#%)$('*)&#"&"&*#%($+'($$$($%)!("!++*'#$"'+$&'!#!))!$$&*&$()+$)
@r8548
ANNGGTCTTNNGTCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTNGTGGTGATGTCTTCCANTGGAGCATCAGGCAGACCCCTNCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTC
+
%%##""*")#'#+$+&&++(+###&'%&$)#*!&))&&&&$!)(+'"#%$&*%!&$)"))"('+%%"")#'$+)"%"*!&(()+&$&""&##*!!%&#+!%*$&&"#(""(!*%(!&&'(+#"")!*!)'*!'#*!$('*$'%%+)'$)!'+"'!%#%**&!%&!+&$""(*#'*+*)&%+('"('%$'!""&*&++*+#%$)'$&$!(%$%'*&'*'
@r8549
TGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGA
+
#B-"?C(=F<F:D30#64H*:EE,)A0#=$5&8=B;A(D-D35
@r8550
ACATAGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTNATTANGAAACAGGCGCNGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAAC
+
<=5,E&9G19:%:B'>(--)+11,@3$61:1%@$CE5%HE"+'B>>54B0$B(@-%#$9@('"#*3HE/%")7+<.H72A0!,""4#E.;"@>.9.B,B<=2A0$8?@23(4C!8->A2F3)(
@r8551
GTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTNTAAAGCCGCNATGCGTATGNTGCCTGCACAGTTCACCGACGTNGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGATTCCTTCGGCGGGATGATCCCCAT
+
503E#&(H+E=+*3?FC-+5;.99:6C0:@+G$.B&H@),/2,E.*3+E>E#7<=:"H+107:;1%G>C+59".)D5G)$>6E#$E#4,=B*BE:&031:&/*1525,=;35BE>-=40H=G6)HA?B1.(:$=",CE=D2.A62<50:>$..*4;G:!3,*9//,;D'?41"D2ED#?E5;8C.:-+'D#G
@r8552
TTCGTGATGTCTGCANGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCA
+
8,BF'.0H5)GH)(!E-'D9;?>(7-0@0(+F)$?!&9/1$)+C"#>9=(GG==3G$-D?7DE<4)=6)(
@r8553
CCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGNGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCG
+
=?5":1A&;03@',:>-&5B(!-)223.&B/6:,:6G=%!,/2HD+0'!>!7@+,<81:6@EE2:B@?H/AG3)1E:H<@A.B)1G?1?'?H"+$%C$.
@r8554
NTTTATAACCGCTTCANACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCG
+
'A0306(8/D>2G('B)53DFE76-/B6=1!@657,?*@=--#*-(58=48F0?.(/E"!?&7./*#A;C(43*+
@r8555
GNACNGGNTNGACNGCGNNNCCTGNTNTCACGGACCTGCTNGGCAA
+
)&$*!%$"&#$$!")*"*"!)##&"'$(+*%"+("'**!*'*'*$(
@r8556
GTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGT
+
B5'$*2)H?BB64E3+::5=4$BBGBAE7H-E0DBE4&<%>
@r8557
TTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTANA
+
'0@*52((86?.E6A=9,A9!>HD;6D277$6;2)?,+<3"=E65/"-$+>.0*6<'5-9'5D+H943A1@2<B6E;65?0?50F2'2,";A53@3B4'22"#6"C
@r8558
ACGCCATCGACTTACGCGTGCGNAGGCCGACGCACAGGAACTGAAGAATACCAGAGACTCCGCTGAAG
+
DF6280*2FF'*4C>>7&3@>*BDDG25&'7="0-$%*9)?0/,>*6$6:9C?;G"/85.46A650+(
@r8559
TGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCA
+
C,=C$6>('EF,/E$;E-$$7/)$@;$4(8!6D.6<2G56E?G@+HD8;6D!<<!C/8FD$4+G*G"7"822=G%&41F-85G(F6E;$@B&HH7G"84:+).D!G)4->&-;FF+)27;$<F
@r8560
CCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCT
+
9,6!<5A947$#(A3F<';#>/"A9."F1?-!2BF@/?#&G@*';
@r8561
ATACAGGCATTCGGTACAGANCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTT
+
)*+(&%'#+$#%%'+##+'''(+&'+#*+%&(#+&$$($#*($*""+*&+!%$%#'")#((+&*&#)*#%#"!+*%#&%$""#+!(#&!!$)"'+(*'+$)!%%"%)"*(%
@r8562
AGNNCCTTCTCCCTGTACCTGAATCANTGTTTTTCCGCAGAACACTGCGCCGGTATCGAT
+
!*%+!)"&()#(&"&"+%)+'('%"#)($&%$(+#%#*''!())$%%""'+)"&%"*$*)
@r8563
AGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCA
+
02;$2.:20-BA*@5)>?H+'8*,0269F!E1A3>7&<$1>#H1,!B3.8/$8GG-=4.&F#E6>>6B(>(9>$&EC)39*$>/962%
@r8564
GGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCT
+
G)37;;8%#$&8C"A9:<=<D+'%"@(/<5D1604(;A*('5D225>)>5:$6>99+1#%6(:?0F)%%B
@r8565
AAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAGC
+
>=61!CFCG'@=,=-</>3=)&:%84H;$(BF5-/)<%7&$3:FC)*7'9!.EAE*&2
@r8566
GNAANNGTAGAAGTGAGGCCGCATGACGATCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAANNCAGAC
+
(&#&"#+*)&$)')+#))&&)(%'#)((!#'++"$"*#*%"*&'$())&*'"&&&'$))+!*)$**"!%&%*!"$"#)"%!
@r8567
CCGAGGGCGCGTAGTTTGCATTANCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTNGATG
+
!>&*DE>$&?-<$.*B//!6,79">3/)(1BG@"<E!HE+*2*">%"B76"*+4F&B6B:D2A;6"-"@29*
@r8568
GTACAACTGGCGTAATCATGGCCCTTCGGGGNCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGC
+
A;&E,.":%/)",51+C?A1G1@4C&2%D#.!5*#3<CG)@10&(FAB!$$@=%;ABF8/&)B@1.C88(B?+2<6#3(.:>B32,).><&@=:@7$*'-H--HAG#A6=,!&E=.61D95G;G=42DF/+A2E39D"<C6AH80C*/B*#8539+&'*@
@r8569
NGCAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGG
+
'#!+"+'"*#&("***($&(!(*'*"!+"'$&"%)'#)&"%('&%%!#&&)!+(+&(')%&''(*%+%!$")+)*!!*!)))$!
@r8570
TGTTGANCAANNNTTATCAGNTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAANGTCTCTTCAGGCCAC
+
%(&(*%$)&*$)$'(!%(*$)++&&"))*&&!&!!*&!&&&+"'($()$%"$($'*$&#+!#(&(&($#$*''
@r8571
TTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATNATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCANTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAANTAGGANATTTTCATGTCA
+
+C)7%.D9!"/AC%/B98<1%#2;08E*>(>?@G-2=C=9844-!F+>:,?G/20=//H%2(&%4+&>!:!E3:=H2>16+D;!+ED@8F=3%C!/F4CD%9/419A4#87*6E4/*69=#!>C-/(!;!E&:.-;-+$&=A@>&E(#+)-+=.9*#BH9&2+9-25$%)-3B412&%%A!BA$C$/4@C6#7+;C@5.E7D5#0.2C<+<D%G1G=B!&4=#@/%/:3>,.G3>!D*!!
@r8572
TATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTT
+
8F?70'-H;)499:-@-%%&C4;63014<:D<5-<-H-H01:
@r8573
ATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGATGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAA
+
=<=!#2/8E"(5'!?#-,#+@</4-<%3>3!2'G52<@C;6/*$<1*2)$C9<0H@F@@32$905?E=H)<D6&A9>?!2:&"?%),A)!<+;%C'@.G=,)8EB82<!03:A$H3?,H;.G2(53&(@*,/#C->46@92=4FH(/!+G-&@7-H,GG304,/D9)B'8%$:*43')'5F.)>+)FE6<A-5(?)G:5%,7GEF+7.%?8<22D?9E55HE")BD5@H"F+0
@r8574
CAGNGCAGATAGAGTTGCCCATATCGATGGGCNACTCATGCAATTATT
+
0@4C!1>?G2):,+==!&26&G%,&+40+:9!,1GB.:4B8-H>F<HE
@r8575
CCGANTNCATGACAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCC
+
'(%$'(!!(%'*$+**&!!'&)++%+"#'%'+("!"&#$#('$+)*+$(&$)"
@r8576
TTTCAAACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCNGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGC
+
4+7#B?!"'=D0;+!%44*B8?'1-D,%?G#H7;=1%62/B4,-:(?6G9B44/9&<B'3/H"A3@&3*59?8DE!B7'@F18*4*@?3'@/9:<0=G8#CAA"H(6@&E'H3)?>;2@../9"F(:$1"=.1)06,G'6H590#HHH@-.208;86EA.=4*%?1&#-0!(D,.D=HHH"9
@r8577
AACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCT
+
C%+=/1@+9C*#92@3@#3,(0>#C7C7+C'8<C!2:4>)7):1?7>,)/+1&2=#3<!.;=1+!;5CHE*(.!F1DE#)='3A&FG5:5,,<F&+(B&.*;50G)HF(4)D4"?%D*H#<<9@;*;.5H<?CE1<<$"C6=4E,6/*1B*;7@$!(911A,@8/D$C8C!.4D6+?
@r8578
CCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTC
+
'()'')(+%)#'*(!%&+)!(*%""*'#!)(%(&!%$&))%!$)"()(#+')""$)#)++()%+&!$'"**+("!($%#+##***+")*#*
@r8579
AGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGANTNCTCACCGGATGTAATGGNGGCTGACGTTCCCATGTACCCGCGGATCG
+
+"=-8>2'-;%#&=H$F<CF,G"=+5@?%:-15%:'1(H*.%$6$4(%G:/$+*?C,=>9.7&G2D?3?*H5!!*HE<;+"9<ED9!=<("7%($>"B3;&><*?-=:,C(>D-1B)+4*$D4?-+H07
@r8580
ATTAATAGATAAAAAATTCAGTNAACTCCCTGAAATGTTATTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGG
+
-#G:$F*!!";?D-4-+0%;'/0+315EC@@@0'65<#7$,FH-&G+/@H!;(/-'F@357B=(=?,.$A*.;;0"A4@4;%!;E!A@E4B+1A0'
@r8581
GGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGNTACGGCTGAGGTTTTCAACGGCCTGCTCA
+
%>,GF!356G*=>4E&">-C787>"938F-25:C(-/6"A'@.*@'7&G#.?*/8H->,1#?<!":&
@r8582
TCAGCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGNTCTCTCANCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATAC
+
@2*>)-)>DD@B2<;3<7=-=+1%72/F>,*-)..=9'7FG?8-9*7-3#+/&@7%(0#;B!*&:G=,(",F<7&%>5!''BBE'..*+7#0A>G00CA-!:8=/!-';=.3>=8G:>8H*G?&H,4!<%.5288A2%:28>>&@3A*+-$::;93A"+!$D
@r8583
TTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATATTGTGGGACAGGAACAAGCGACGCAATGAGGCAC
+
=<8F02:8A?$2#,@)("$C:@.>=4>F39"337)B-1%C'::;:#4'E0:F%9057>E;GF1!C*(-1-:1F&/.;%@@H/!F(GA:(?#31"H.<?/;;<E1C:>*
@r8584
NCGGNGCNAGGTCNACGNACTCTTANANTTCTTCTTCCATATATCACNTTAAATAGTGGATTGCGGTGGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGT
+
")$)$$"$)&"*'!%%*!#&&!"%#")!+*(''""!*#$()"&$#(!&*$&$()'*)!&%)+")!%"*$(+)#&*!(&#+$"!'+!+#(&$#*%)*)())()*#"%'&
@r8585
NAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTGCTTGTTGTTCGNCATCCTGGGAGACTCCTGTTATCAAGCACNGCACTGGTGACCTGGNAGAGTTTCTGCGGCAGTTAATCGAACAAGACC
+
*+&"+$(""'#+!+(#%"$+#!#(*&##+$#%+(''*%((*)+*'!#!#*+#%'&("&&'#+()$(!')"&&&)(%!('+)&+#"'+#%+!!$"+%"+*'!)#()%('(""$#($#!'*++%)%&!#")(!"*
@r8586
GCCCTTAAGCACGGCAGAAACTGCCTGCNTCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGG
+
;**&=*$)#@=,>BB59,3"B>92;<G%8'>1*-F,/'1#/-0)",-?".?-98;$./,"7+/A./?E.*C>H55BE:;/=/$::BF&70,#:G;&1+G<$6=A%
@r8587
NCCGTTAACGATTTGCTGAACANACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTNACCCGGCTCACACCGC
+
0>5&D)E%!?684$#0><G9(4&-%A>%8*1%8F*A0<2-"933))''(7*$H-:,#2/%G6<"",6H9;B/B<5=2/1(8%4H2D%:7.F/&7E/D,("FH%4@(09:+7
@r8588
NNGNTACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATACTCATTNTCACTTTACGGGTCCTTTCCGGNGATCCGACAGGTTACGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTAT
+
!#%(*+#'$(#*+*!$!"!"#)"+"*'!*%&&(%)&*($*+!')+$!($%"+"("#("+)#%#($(+&!'&)$'+'&!&$!%(##$'#"")*)&""$"#"*"#%$'(#%+$+#"!(!*+(+$+'#'+#!(+#)$&'#%*")!()!)**+)'+(%)&#%"%+&*!+'++'+%(&%!"'+)"&")$"
@r8589
CCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGGCTCCCGGACGTCATCCGGAAGATGNCTGTAGGGGTTGCCATC
+
G.%<"-H/FG9%E&(GDA:7C7');5@1:,0F!71D4!7))7%?*;G$02"?5B%6A&!F?C'*0$(+=:H$A@+/&2"#?0CG+:&)H%7*,/.;.9'GF73=CE(=H1+H;)-"')/B(@1/'H,+:@
@r8590
GCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGANCAAAGAAANCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCA
+
C!3B"&':)!,4%*B0H*8E/584G"H;A,D.)931G.'3(0!GC7&C'*<E;=,,#&/-$B92785+)HE./=B2=H""1;97-A'F6=)A/,C3C/,503&;@D@@A408>*H/GED*$$7%82C%!/HD=854=C(4+35<73H'4(+$6HH!?E';+!#%(!F,3>9,<*-@".EF20E2:(&'#BB.5A
@r8591
AGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTG
+
)=)2,F$.(6(-(!2G'%!7(!@<#A1"*86E>7H<3>GD134<?C*1A=($(*>.%
@r8592
CGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGNCGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGA
+
1G'-G"0C1$H=7+086($46A%7.&!!"+=:@F%*H?7E.=:,('?0>#?#F/6,,(?C*?F86*6!!1GF<?HG5-CH(,6H>9*42%$F@;"8E:<A608C
@r8593
CGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGNTTGACCAAAATCG
+
0=AF+H<F16H18>##H+1("/?4%/.@.'9<#0HE71C@A@HF5-<D6+,5$5@07G(%&C<=/BA,4F+5)?(-&A:2"D09#-G>*$4C;1;<G.B/./'+GGF)GH0)&2(:*DCC%G=H:B@?$#$8?HB$BHB.2,%;8E.D5',H%B0B;4!?A%'<.:*3)%>77D88%D)7-FH3
@r8594
TNTCCATGAACATAAAAGATANTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCNTGTCAGCACCGGGGCTTTGGCATAATGCAATACGTGTACGCGATAAACCCGGTGTGCATCGTTTTAATTATTCTCGGACACTCCCGCAGAGAAGTTCCCCGTCATG
+
A-%%9@'.=:C#9*?-9D3-E+2'*8B<+G3"&D:9.HB$?+2E*AADD*;),F+FD;<@7(*!=B#?>)D)C:?4&&04E9+!C>55"E15%*$BC+#*;#84"&>)%*C>H113;<7*@"(9H(@-C.-E3(0$?$;9!+1+/D?7F!.F.C"6F0E%E>)$1C*??/A-%416#2C8*CF='F7A+!,B+%6=$B70A!#03H/B.&)(-<"A;:B'G83
@r8595
TGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAA
+
E#7>$E#828<65G'@A:=(11E$DG.="??.A599>D5+&E'HF
@r8596
GNGNATCAGTAAAGTCCAGCTCCTGCTGGGGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCA
+
&"+&&$)&'("'%%*+")%&#'(!$)!$$)*(!%(&+&*"#(+!*&#&!*)((#")'+$+#$#%!(++#&'+!%($)$'*)$%$##"!"+*
@r8597
GTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGNCGCGGGTCAGTATGCTGCG
+
-;!:D/2/>:,?DDG%$.9B*B#(79=G.)4G.$$(C9:,HA7:7,&@&,>)"/F,68'A2HD+D(<D6D3'?&-
@r8598
AGCTAAAAGANTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATA
+
1D/+*B#-?B@A:H;0>3$??E6A5#5#8/#-F%5*&1?-H'<+<"
@r8599
ATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTNGAAGAG
+
:49@806*.4DDC;',CD;B/B992DE*>9"'&,0090;'2.#E3?=,0#6<979CC=E,@G<.&#G9H?9C+H3G<
@r8600
NACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGNCTTTGCCATTCAGTTCAAAACCGCTCCCC
+
!"4797$F;D&>%E*>1A'C!A93&%G,'(4516;600&(9GC0"E-D).@*C=$4A'8AFE*,+5:$#3,+F$
@r8601
AGAGCATTAGCGCAAGNTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACNCACTACGACCTGCATACCCAGTAAGAAGAT
+
$D9A.CAB=&8F@99?D6F,34,)'2CE"79E!*@$&GB=-5,,@.).E+#@E6!*(A5FF(21)1D2=.!/*;68#),@01)4G*>DD.<5+C4F@GC-+E1&/9%''%.B),$>H+BB+E21F+8D(DB'<E-&02D7"?4F?%
@r8602
TTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAA
+
7@.:F4AD7DA&&A*(>8/>*15-19E++(:6&$-$<++8
@r8603
GCTATGCATCGATCATTTGCAACGCNACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGANTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATT
+
?D*8$B<GA2A;3/&>037$<F#;AH,H=$.A,$H"%>6"?/??=$@,'A@%G%"5H>F?"*+-D,,2'>;1:>-D&##+*4C2*#7*/F++)9)4E=9/")+3"&/1H->A17D'';/6<#C<?&##)#G:<<!4D$-*5D@#3->C6:',(FF8-A="D14GF!+"3'C1(DB"&86-E"5AF!4@808,(4=5504&<<E0'07&D-#.*B4D8<96"67(=+>(F630H
@r8604
CATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAA
+
=*E:<1?!(GD3,F!(C2"/.H1(@=+?F<"<!$+2-2E/57#.!4+"6/)>A@A@(B@+<E+BG8H@D?/',D13';#'!65G,F8
@r8605
ATGGGNNTGCNNNGNTANANTNTNTCGTCAGGTTGAATNGCATGGTCGCTGGCTGGATGCAGAAAGCTGGA
+
!(')'&()*%#"""!)("(#)()%&+''#%$$'+!$"#&%'&#+'*(&)&+$'%&%*+'(*&'*'#&((&&
@r8606
GAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCA
+
'E:G0)&#8$H)#2DD:46&.,'@&HFB7C-'&/*&!0>##*F>
@r8607
TGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTT
+
.?H-#7+<7;6!&+F%GD?"-G-2(C?55-*A5"4&6.%(9B-/$/81:(74D9<#<.447/?4)>67D62
@r8608
TTTGGNTTGCAGANNTATNGCTCAGTAAANCAAGCATCTACTCCAATAAA
+
*')*$)%%%$*&%"##&#$*#*&&(')+')+&!#!&'&&'(((&')#(!(
@r8609
TNCACGTATCACCGCACCGGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATTCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACC
+
!%3;*'FE*+0/E:)0@7G30*:!.170DB-&G1320?82F*/2$.3;7@4?'?5E@.A+%'='&@):&%)(CH%+>F%2$?@G?42!):D4-D859880(;5B?'%)<)=(,(#=3-,A0300%%E6=D77CA<5?@=$G.1:E%1?=9?5=<%-28*'7/)C493:-02@;4D*B:$@$!A8=,F':FD'F?#6:F='>:*D#@>1"&0-(H6;25%+!6/-@"H9)='6+#%8'++4.66&==EB;'F;0B*3)&@9-*=%H*A=A7&0"5(=:3A/,@B8#1A<D/(B$H!3*E:G,:E$)3G,1,"1*HFA>35.'/2+%*+A;A;#&H;8
@r8610
ACATTTCANTCTGCGTGNTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCT
+
6.0</+#GDA+H;':,B6,(@#>)-ED=&0+D5+>7-4-$*5H;1A*%90,$>+C"&9@;-06@=B;<=,3<D=-?581A.A&#+<B49;F
@r8611
AGCAATGGATGTGTTTTGCCATGCGCTCCTGAAACTCAACA
+
C4<311C7-,6>/83"7;9@.H+;E99A7,,4)E;-'+*>'
@r8612
AGAAATGTTTCCTGTAATGGAATATGGGAATTATGTCGATAAATGGGCAATACGAACGACGGCAATNATTGCCAGAGAACTTGGTAAACATAACAACAAAGCTGCCTGATAGTGGCCTTTA
+
0G(A;'9$59!',*&A;8;>**/=09$B$(HD+.'+:=(.D/$D(&E@")H8+B@.%1%$++5&:;?,,4!@&3!,&)A=**/*37>(G.9<G@7)!E#5F8C'F:04%!-1,G7-+--GH
@r8613
TCTCAANNTTANTAGGATTNAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTACTGCTTCCTTTTGGAT
+
)%$"*&!"))'$#')&%'&'&&'+(*$#"'&&'*$'%$!(&&'"(+"!##)#!(()"!"!$'"($(&&(&&*(%+*))&
@r8614
CNNNACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACA
+
*$!'%+'&#'&"#''%$&!%&+$%$###)*%'&+&+*%(&*%*#%%&
@r8615
ACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGNACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGNT
+
<D/?4:F2(C%B?>4?2:EH$EA==55#>9:9,)#*7=>@9B)"865BD=(C,+2)',8*A:0C#F00<02!5H30?(#+G.)?BD%7(;6%0&%?-G8<!D?A<B6':?F>0H51%/F=86#,FD&86==.;H)@,$$@1"$C)/!(>-4-955%-6@;70##"?*59BD2G0+#B@!G$&A@>#>4
@r8616
GTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCA
+
HG'C=4?F=+:F?43D,&D*'75)F/*"9F26@@"&&E-2=#551)E?0G*-*8:1H/H3C.5:H9C9%'1)>&(:3+.0FC,DE?F2?*'1%>3@F#827+9>+23+!
@r8617
NNGTGGNNNNNNTNCCNCNANTCANATCGNNGANNANNNNGNNCAANNAANGTNCCNNTNTGNNGNN
+
#$"$$#"""#!#$"$#!"#!$!$!###$"""$"!###!!#$!"!$##""!!!"$#"!#!"#!!#""!
@r8618
NCAAATCCAGATGGAGTTCNGAGGTCATTACTGGATCGANCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCNATGATGGTTACGCCAAACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGANCTGACCAA
+
%0;F"6>75DE;A6%,E*G85=+7'?,474#5:50,5>(*1&A/,=/7;*D3:=H48;F%@20@2#?$3'#&H:9DF9"(>!A31D>')G,.>+G-%D@;@4GF5(,4.-(/E;EF*G*#9!/'-'B*D71H(,;8?)<3&+#440F*/5=5%6E"9)2/)>!G5=:/"+!D/"604?7(>1<;+9C>:D2E(=
@r8619
TCCGGCAGCACTCTGGTGGCGACTGGCGTACTGGCGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGANTCCTGAAAG
+
?&4(2F32H*0B1#(1=F>"78G5%A,E#8.G><&DC9$!D-7,"A)4F"(/0"EA>6,%-.98%22!4+B-('=#F!:&:?".,G)?/3"$0"54%).*%(")-F->!5>>D60D$5,'?>FC!@?A@7GD,DD+7<?)=,<%C#&
@r8620
GGCAACCCCTACAGCCNTCTTCCGGATGACGTCCGGNAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGG
+
<G??(=;>?:9,,B39,+*B'+8$@7=<$351&61<."2,(=7?4/7-&!/!*H/)-(3-FG<7!6E#:D-*6/G?%/%',*;D>@B'@<.A3?*'!$;,(D?@F<=7514260EG&2=<7833&&.
@r8621
GCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCAT
+
89E16#&@H>/C7+8G%/=+CH4&</=/8G1)8=H76%E#8CC?"D.9=67G/-E:3)$<@G/*+;;D2F<=)9$>=>2*A<1@B,(0$<EC+/?*+G#(%95D)3-C>9:CH*A32*!%='"D-491$(59D*!/;<D6HC383?*C!;?@&3,74?<)9$5E@F)=A'9G&+*1%D*%06#'DF!>C#582:!B355:4@&+
@r8622
TNAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATCCCTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGC
+
*%915+G.:&F?86<:8AC/9C6)C'@)/--H,7!47B!(0.(HH)1%D<3+A1GGE'9=H++B<.%0D#+1:+>F22=,.E&0%",F>
@r8623
GCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGNACANCCGCTCAGGCATTTGCT
+
GF+)5:?-#H"/82;C:0)%!;B"F8AC<*8D70%B/!<7;,63#<@18=--($*>
@r8624
TAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCG
+
(3B3,=B8#E.B>&:H!6C?("A('DG39/G,$FG%=D;)99A"=4=<G7"
@r8625
GAAGCCGTCGACGCTTATAAAAAATGGATATTAAAACTGAAACTGAG
+
B?/CG<<.@+0&9D!<!<->/E*C?,7@$*-*(F)!'B#/(36!.G@
@r8626
TAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGG
+
?>D*7'3#*B>'3372<:B,B!$,99B-!&E82"C=@#+@?,7&*H7:?B/+&;12?/
@r8627
AAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGNAGA
+
H,-EF3#6';+:"4?BD:!C1<6#A)A:1H=:D:>G;H:79?45'BF4@/B&=?3H7E''8A5
@r8628
ATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCC
+
F%-'4DD0H>F3678;FD5'0718B7/($.;<C?,"H1>2.780?;3H
@r8629
TGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTG
+
7++@:%94A93D*<1/A-6.1;B#D-:*<?@?,@)&%)D"(4=4"#$?
@r8630
TGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCA
+
9/+F'=&GH##=H.96:-">+>G%F-DB<8@&G*).+D=3@"29=%D-'?&&?C.$+"#37H@F+2)22$>D/@,H?",&,'2C/(<(GG6.?%>662(2=/@?B>
@r8631
GCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTNAATCCAGTTCACCTCA
+
G:-('.86%)3EC@9H*B-#+;B53&<>F99=*:D"6+<7"C+:4A#0%<$D8&D*;!/!=$3!?"E;:
@r8632
NGGTAGTNAGCGCCGCCTCTTTTCATCNCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTNCCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGC
+
")*&*%(!%%%+!"$&"$)'!((&(""&)#+"*&)***$*&%'!&(&'"+)*)#!"*'&+!**)%#*'$+#"+%!&(()"'"!&$&)&(!($!+"$())##+!!+'+$%%!'&%
@r8633
CGGGACTGGCAAACATGGCGCTGTNCGTTTCGCCGATTGTTTCCGGTGAGGTTATCNG
+
)-@?',@G'-*H8(6,");;E19/&;1/5;9*G873;E7@F..0*8)0106/>/8:%+
@r8634
AATGGTGGCTGACNTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCG
+
(%.?7B30?,H"2!(?178H7'%3D+5;%"$0;,&@/'.@8F(*"@F@G)3%C?".G$-#287=-'A-H?"76:11?G$;5F@"(?*61.%&60-A<&;CE5=.A=*1%","20"1;!2*G/1'F3B1?!C"&2(8?2=4*BG5$):H<6"64FF../2H$/$$G"
@r8635
TTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGNTGTTCACCCAGCGAGCNGAGACGGGCAATCAGTTCATATTTCGTCATGGACTCCTCCACAGAGAAACAANGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACNCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCG
+
=$,D3:0!4+3"-;F5<1>94/?"%A6DHGA"8B2#G3>HDF,$A9A)(:)/A+,B-;#$9$'E.:)02#B#D>&6$86%='D)#@46"%;>A%/9GG!+./'EA!#&EC8#>%17D3.C",#C,'+/!.8@"E@74="%5=A-CGD.'ED:%C/..GA;-72(#8CF()%*E#,)FDB&2@&82>*#1.-1;?+-<%%0(2HA?7F9/G9>G8;
@r8636
CGNCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCT
+
=CE&5-+#;G),2;GB*?"%//DCB;':=B34-3A'A;-6:'0+G4>+/#.(6"*+/**62H$-13
@r8637
TGTNNGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGNAGGTGACGCATATATTNCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATGGGGNTNAAACCGTCTATGACGTGGCTTCCGGCGACGCGTT
+
##%"#%&++)%"'!")!(*))!%&)!"##)'()'#&!(&(**($(+'"++%+(%&*'%')*#$&"*(#"%!(*"!+(")(%)+!%))'#)$"""&*+#!$!($'!(*)+&'%$($##+*+$%('&(%&++&(#%))'(&(&#%")(*#$**!"+*)#'$)(&)"&()!%+"#)%"$"+(#*'&%'&"&(+!"*+$&(%%*+'%(#*$*"((%)%*&%+&(&#%)$!$+&*)#'+'"&&)"&+''&&*%%#""&"&)&%$(&((+!$"'#)!
@r8638
NAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCAT
+
)>8#2C84+)84<?-+B62,/-9C321.<2+>4*2?G7'@E2>@54#!H*7&!68B!
@r8639
AAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCACGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATG
+
'5-H59$5!##9,0?3C:8*5:HD?<5!9A!/;E64:,#46HB%*..GH*B&</$B)>,?A69)=@8,?999(%"=B9?*C4/>1A'/H12A0082:,)764)+B!&AC&<
@r8640
CAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAANCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACA
+
(E55A'G-?G7ED?-!/!#=9E;%-:=$9(-CG,H5C#&*9B<:;0;E%!:C-545*+-.EE?$,30%%1!E3@/FE&5%02!8.*727)C3#)C!"'A:-G'
@r8641
AACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGC
+
;(0=9*:#5HBG6/8/10%4*>%7)+910+@.;FF?E"1"(H4*+4.",C*,H*F:.++=46,.5:?8A?;*.HA@("1=F@C%&1B1$"/8,D5*
@r8642
AACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGC
+
G%1-**,:A9BF?<.,>%B'CA+:0'/0,3<10/(B9*F98+@F5,,((998%F#+FH"D5$2326E
@r8643
CAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCCAT
+
B")'.>B-=D.-D)&!=)-A9@4F;GF*<)/*C9?,%;11>/""H>%?=:<E-/9B>==?/&A#FD#(0A&"@58=8+>615"5+%'@F:D2"A>:'->)H'BE&70&E8)/G?6&B
@r8644
TGGAGNTGATNTNNACTTCCNTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGG
+
)))"#%(#!('%!#+*!*&&&++#%%#+$+"#+&&#(!!"+"+++'"%)))*&!!!#%+'%(+')'"#%"%($%''%)***('*("()
@r8645
TGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAG
+
G"%+B$B@A%F3*3=$.$BD2-3#7=?H1GD4@B9.;=57$DC8-5352#!=2'-B990,3+-(C#B&%)2<DE"0-"F6"A32
@r8646
ACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGT
+
-7!"7-26,-=F74.#E.>'-BG'F.;1<!BEGC84'AB3,5B/&@#B25-"4*8.($&"'#8#C1/D>622B(;490*&9)!-E664A+'/512.%2;D8*(05768
@r8647
GGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGG
+
17+$$?E<D=)1<2)@:2CG%(/,*"+5>C*.+;G.D7C61#3&2#!
@r8648
NCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAANTCCTTACGTTATCGTAAGCATTTGCTNTCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTC
+
7?2$3B0DE70,)'%-?-@'1),3E!59C6*C3==5;H4C6)H$?6+)@7:'G'9=5(&#48.2G3$!B@348?$GF'4EH(C#>5(D9#27B$=)"%D9F0F6,G,?"0;@7C/B(F9#(@(@%6=84)"(=$$,*%?8FD&=!.6+"E9%7F-558H9=H?@8CF>++5D112542'=
@r8649
GACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCT
+
(&A!:#;@09B::/04C&AH=,$(/@4#G")/5FG4&!0C5@;A*&"3)%53"GCF:917G8A&B$11$<;/C?/$)A;+=G,2$7F">6<E-0-A6.F!1;:F;>C)<HD7-F<39/#
@r8650
TCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTA
+
86#GC53@,7@8F0-),85,54::!=":/5E<*%$A!G4/0B+,.0E'-2*0F;2"C+D&.@H*5?2!7A<8;51H.B%EB++.5,B/H@4>C>=#"0+AA;*,3+,E;..!G;72,A$;788/5(H"7:%"("!;%%49
@r8651
GAATTACACCGTAAGGCCGCAGATGAGNTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTNTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAAATATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTT
+
@@19;:C"=6#6)G(1A=G:>>3=AH!E2)G<@,D@>.8A&<).B)/C;#<5D+=C.H%.,851B01&!2624%8@6A=G5#>>5D/">$DA:=$7"F+G6136/A7CDEB*$':6E80A?"+034D2:0D-+>#;66>)>:(!;!3076E6'%7527:4F,(%"@6C%C-'6=;:@%6(#/0-@!+."EB"-.E60,BDC'C0@*$"42B+%E/F4C1A!617*7!6"B@)<=GB*+@E2+G11@=DA8$/B33A*E=>%(BHH3(F*6!C1@)@</64>(7#7H+26%%.+3E51!"&6*$6G%EH:44AF9361+)2)E(
@r8652
ATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATNCAGCAGTTCCAGCACAATCNATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCNAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGT
+
>E0./(4&D8A.)49"(-4)+(,)?:E-C*)($C?(F>#,'E!<A&716*HE=7B@74,=+?BH;*'<;H!*)=(D0E2"'&8/>D?/49()<0-%H@->!?F="+*>;62B5?177)5?"%B:6$0A:);#EE"B17:76%**9".->H&:0@>-<8E*13=FE$HH!@??'AF3H,'%GE8(92(;B655D+=
@r8653
NTCATGCNGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCG
+
"%$(&(%!*+)""+!*%(*"(%)+"+%'#"&#"+**!"'$$)*!#+)'&+&'#
@r8654
NTNNACTGAGTGTGGGGAAGTCGTGAAAGAAAAGAAGTGAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGATTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGTAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGGCACTAATACCATCTAAGTAGTTGATTC
+
!!""#)%&"+"#"(%%$%"+##()!%*")%&"+!(*%+)$"*)!&$)#%+*&+"#"+*$!'!#)!$&&($$&*("#+(!++"'%%''+#*#%+'#(+))&)#&#+)$#$(&!!(+#")#%!%&%#!"%*&%*'&*)#!&)#$*"$'+$+++)()!!"$)#%"'!+&&!)+$*'$)&+"%&*+&&('&!+''$(&+#&)$#&$!*)&%!"&'+!)')%!$&(#+%)&%')$$&*'+$)#)$'#(%$%
@r8655
CTTTTTTATTATTCGCATTCACCCTCAAGCGTNTTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACCAGCGCAACANAGCAANAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACT
+
1$C$E'&2D!=1.<2H'9,-4:F(&%E0$;1F<(@-#E/"6-E88(4)9"+A9'$+2&=9/=69*8)9-$!9?G!99'+':,),$4@.E:G5=3C1;$=C7!>>510C7%"0*0C@48DC$7=48)8*A(7;;%:;"(C"F(E/4@%F..H.)"'G65=AA$
@r8656
CCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGT
+
.<E*?F(>B1%(3C@4.E5E"08-6+(1*-HD$B6B3*F?3-"8<-2!=%!0>2)4084((B!7;7+:'C<85))B&8/3*G((;1
@r8657
GTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAANCCACATACCNCTTCACGCAACTG
+
(*$+&&+)$!)'%"'))(#'%+#$$'(*!&)("*&($$*&##$&+#$($!!(&$"($%!#"#("&!#$'"%#)&("!%&#'!(')'"%#*#)*!#+("&'%&!(%!'+*!#"#%
@r8658
AAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTA
+
1#'DD"90EBF/,7=3#GE?F'!"0/>73!&5+F''41!<(HHD/39,G<6E>"3D'1($G$!4?
@r8659
GACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAAT
+
--936/77H7EBC<(3-8-.1F"0-GH%E;>H;6:$,-0<&,6&*:2>#3:/+<5<C0D2E2A714:-C,&9:6#1@<1)A)6&A)
@r8660
TCACACACCCCAAAGCCNTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCNCAGTATCACCG
+
7&G,GH)3.DE37E<,B(<@<.:9;:3="=:8-1E2,:):=814'.1H154/?A"*)7!91A)AC*=%&6"1C%33(546,)E1$1=&A-C9C7C4F&=H.*"E45.(C&@40
@r8661
CAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGG
+
6(1;4-G61(?,'0#CC><18=<$<+($3$,:2D;5E-'+E-C!E+6%=H@:@;-&+;#%%9**18?7?27H;=9#4E>/@5(:&-6:&6%;3H;=E!E;F"9B<4A06+'0%AG(''+:G$$D/;?8=/#A"!9+D%C25-(1?7;
@r8662
GATGNCCGCNTNTNTGCTGGTTGCACACCACGCATTGCTTGTGAATA
+
$'%&"$'((!%%&))'+#%)%$''(*"&&+(#'&'%)$%("'#(*$*
@r8663
CATGGAATATTTGTATGCCGNCTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCACTCTTTTTGCTCA
+
2"B6EE"F&&'@19)+'322@6=.%3E<-89"ED,&@+!)56@,+:#:9%5;E#:$!#9)<)7'4;+,)-',ED@!1":=E1E9&=12F+?2?<!=)4'3/3?$E08/79%)!,+/&B5E=;F>
@r8664
CCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGC
+
,;6??,:?+0(4A=+/0E8=H4G1E,<7?$G</93;=%F/?>74<6
@r8665
GTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTTAGCCCAGATAACTGGCCTGAATATGTTAATGAGNGAATNGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTNCATCGATTATCAGCTATTGCC
+
*@,3"2F=E?",5%0>>#<$G(58;H,'@?>B4D2-?03#!6C7H!E@A#"6,<3;>.:BC&#+);'*!:C(99'5G#.CB>B;%#3.E@.03G7"AH3:@+:17H1<&4#3<6BB!%*$E4;3-G#.0A7#3+!H<E!+<-F<':*:93$-(*:63@&C6<00?H+=(G?8/;AH1C?05A).+;;F-*"A8:H):A$8HB30B,@,-G/$5!E+'2&%367E"6&D
@r8666
NGGCGAGCGCGGNTNNTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTA
+
')(*&***%)'#"'$!+$*&&"!'&"&%*"&'()(!!*$!&#('))!"!"'&*"$'**)(!"+)&%))&))($*($+%+&!+&**()!(&%&'%#$*)$*%#&#!)+&(*+%+#")&&*!&'%%$*&&%'++&!')$%'%#
@r8667
CCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACANTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGT
+
9)C>9!<4H+H0<G="?$'2)0(,&*BE)#''4$'.8))/&G13%()!,&G-#B>91:7D509F"(3/86#+.%32E)C9F""79)%!?FCH)2&C=70'->3+/4=
@r8668
CACCACCNAGCNNCATACTGNCACCGAGGGAAAACAGGATGCCGG
+
%$&%&$)*)")*'%*#&(%(&'%+)!'*&!(&#'%")")+)$+')
@r8669
TGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATC
+
-A&BC>/'=:A.6:B0?%5C3F20>&)H."03/1"62H+730!;).$+<-*E65
@r8670
AGCGTTCCGNACGAGATACATGGNAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTAGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTNCGNATCTTAAGTTTATCT
+
<."F<8?;6G-5'87&9!G)8A78<)@?2&=5>>7&8H7A@H@%>=?H3#FE6!>@&2;F1B'/"8+?+&>&2+0<74?"!=A=&%.<,D2!2D;.0=02*<=#&875C3FD(?/27H>9-'7A;F>G5
@r8671
CCACGCTGACCGTGGCNTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCG
+
=8!+E#D,@5"8B@">4/7')',7(:65CB?9A5&.05'*F"/:F;A0)8&7
@r8672
GAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTACCCGAAAAA
+
&/@A;7&"*'04BCA;%6*H,)E66D@@B+>A.,46)A8&<(49>*6;=4"?'#B'&3;)@B&,5(#>F5$3@:;.A
@r8673
GAACCCNGTCNGGAAAAGCCGCGACGAACTGGTATGCCAGGTGGCCTGAACGAACAGT
+
$*)("!&+'+!%+"#))"*%!!+*%*')")#)(+#$#*('++#&!"!+((%&&)+))$
@r8674
AGAAACCGNACGTTATGATTTAGCGTGGAAANATTTGTGTTGTGTT
+
DAAH8%;(G'/BH5,:B'*@?:<9'0-A%<=<FA((464G>H2;!;
@r8675
GTTATCTGGGTTGGACTTCTGTTTTTAAGCCCAGATAACTGGCC
+
@;F4.<G"@BF<47&:3$9#&:F2!,:@GB.,-&(+"0%:+":7
@r8676
TNNTTTNCGCAGGAGATGAGGTACACCNAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCG
+
)%#)'*%*+%%&%'%)'"#!!"%$"!"&%$&(!'('+"(&"*())&(!"*)$'%)'"+&($&)&)#&
@r8677
GCNTCAGNATCTTATCNTCGGGTCTTTTTTCCGGCTCAGT
+
*)))$*&%#(*#*((*(+(!)*)')+)(*%+"!%+!!+$&
@r8678
GCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGAT
+
$9'@9E-4B<7E47%7E";F25G"711,1B">5:/;'=1:C$8D;D:H0B82CA$H%/*/(6<>57#8(*,)1)B0(7"<)=@*"BC2GFA(=C@5C#/37%9+G1975E99$AD@F=H>4E+G;'(*7(4H%*90:$.##;D?2?D0H9#%!;>*?'F(;0G0313"1,'54-E'5FH'#F=!'/&G!>4C*%EE3&
@r8679
TGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATC
+
A17617>D2/:&1"G;,!.CHBD1GC35//%G+=@6C=#?;DD?6;""?,-2;6F)CH<-G*,/</"7+>FA-D.07>@AH30/<%<$#1+"5/$06C%%<H;'F:8&36.;-:?C(&18+#((E'4H)G=:$2FG8F5E*C,A33E
@r8680
TGCCCGTTGCTGCNGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTT
+
+#1#6!!834.:!12(:C0?='*!9<"'B/>F3D&#+1DE-A#G.A@3
@r8681
ATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTTCCCGTGCGTTTGATGACGATGTTGAGTTTCAGGTGCGCATGGCAGAACACATCCATTGCTGCCTGGTACATGGTTGAAACC
+
G<1&/2E>F@C')2?#>6<)&!59A,38<9"9*"B41D;E&0",H-'G++?('$+45A@*!DE=G>G,5<&".&H.*=!&0HB5G1?.9:CG)$>5D8)"+$!'%2A>6?H8G,'2E76;;1!C?*?@%:G<D2#6D<C?0>)C##">GGE=<%/!E8C-(*1;?-
@r8682
CTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATNTCACCCTCAGAGAGAGGC
+
G/7;!93%>C(0#;=G+F&'?*(+-0%,A<20>:717/9G>*6#HG,(>#:,8.D$G@%)G,4/B:%+)/(;GEA.>
@r8683
AGAGGCTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCG
+
*')#'!&)+)*#%$"(*+*+#%+(&)%(!+#")!+(#%&#*)*$)*$$#$(**!(!(&!&)+'
@r8684
NGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGNGCCGCANGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCTGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGACGTGGTGANA
+
12H4.22:&<4G21;8/!G1*":D/2*9<!C?39-H;43>%;>D4F(?1888-$/9@2G2FA#3F7+=EBC@GD1..BB-4(#FE2B==C7+F&):F#20D!'H34=;G%HEGF+.E5C!!C0EH1/6?/=!:D?D5#.'($@2CFH01-)6;::=H(331&D$,6/+G)B.A*4>5!D??D+H)69'=;;)@=H>:-)84>C4(3H@=H,74BBD)$E'
@r8685
AACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATG
+
1=)711>9'E,&FG/10&B!<;!/;>(E;.9+5-+7.*EF@EE67*%DEF/+0:3?HA?$@9.D))#"8&(5/?C.D5>/",).2(');A&%44!,"8/<75GHAA-C0*%(B8$$-><C.EBF0'B,/,0,;'BD!<$H/B60#2'H1A#"C,.B
@r8686
CATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTA
+
!/@>6?:H/>(D1,#E2;$E9@=1*$$=9=(&@/<!'7HECD<24=2?;9:&-5%%@D16F"@-.-4"A4328><D:212@,3/$->.6B"
@r8687
AAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTT
+
>/1#/0E!-6B),F"+=*3C#7F0<1/%3,?2%E/0A:!@$#<@;53B;+.E&@'";%$@9:661+979&HF3%G!45DH:=@*3"
@r8688
CATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGC
+
%$E@"#863G!7(9:A<;.A">"%=E.1G21&&&AE>)/61;F'@'(67=@4))'C>&-'.BB'/**8$///
@r8689
ACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGNGTTGCGCAGTTTGTCTGCAAGAC
+
112(?8/E="<7>(@-?2*5*+;,;E'F%;!718#*?B66;%64A+199%-!FC!4#GD/AA#3439G)3E*!">1#06(;E*G"EC$&E'!D!&:A,4?%4@5:FHF6E>F0(&8
@r8690
ACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTG
+
D(1='&6;H-17/+35(:9-F%2<H.H(8,&5+.2H2,:"8E=,7G=&BGD.8;:-673'6$>%C#+$>2
@r8691
TGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTANGACGTGGCTTCCGGCGACGCGTTATTT
+
2@18"7E+FB>=:;+G7;41H<1-+>/B*$FGE=3A+@!B'4(40>@;/-"%:-:H+%))1'*;H2HE&&4G3@)7
@r8692
TACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCTTTGTCTGTATACGGGGAGTTCTGGC
+
5*!.&A0:HD(:C2E'"@%-%)9/21'"73.=G#0&BC',"?":15E(1>,81'.C+C$).?$'5"A+5$H)&41C"5;?/:D%0.,7H07@'0,2GB(0)!&>
@r8693
CTTCACAATGGCACTCTGCAGCTGCGTGTTNTGCAGCGTGTCGAGCA
+
0:G%!B;G;"/?6@5D>@8?0>8=&B<99G'4*!D-84H&?7E8%('
@r8694
CTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGA
+
HE:!'C#.*?#'4./H#;?'92H?$14*!<<<-?1GE--DGE(*14>@GCG*,%1@;E,%)(;"EA,#F.=#-G;BF6=B"$9!D='?$,)3:%$)6<?BD0>D#A;1B5,5#+B2.015";=32F/,3:&+@>"/'<"*H+?#"2')1A/B1=1@
@r8695
ATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTNCTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGA
+
(/?5H%&-@=;;4?=6>8'6A9;&GD-14+7*E8#);/4A8&F1A7H4"9G3*:#%&,",1!C)5D#;D$D?9$7!;,0/.<H$#&>'-@9/)+-3))AB+-86E$9(*D13@;".4?A#DEF
@r8696
GTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATTGGCGCGGGCAATGGC
+
+&'++$(&"&%+"'!!"+)&#")+*$"&%!")!$%&(!"'!*+*&)*&()'&(
@r8697
NGNTNCNCACGCTCACCATGANGCGTTTCACTAATGGGCGTGGCTTNTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGNGGGTTATGATGAACTTGGTGCTTTTGATCATGATATTGAACANGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCG
+
&%""$#!+(')#!%"+%*)&+#!"#$(*%&$$&*+&$"$#&+*(%#+(+(#)'"#*%($")*!#((*#+&*$+!"#%!'!(*)#&(#&$%+#+''%%&'("%+"!&!'%!#!$$+!"*%)#&!(&&*+")""&#)$(%++)"("($%(($)"&&!'%*''!#%&%(#)"+($)&#"#&!&(")!*(+"'*%
@r8698
GACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACCCCAGCAGCGCCTGCTGCCCCTGCTCTCCGG
+
E5#$&;32''-0,1?!F4"%38*H0D&9!+&0+:3*:0<'=,0C%(@@,9==44,-B>:+;&/6D03"+G:;8#"09HFF<97$:.,0F
@r8699
AATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAGCAACGACGGCACGA
+
809225@-%+8='3D;H&(8")/&+8;2=EF..>)?B1C$47,E>6F'!&+G@G<B7$0:,.9/#&2;4(F*#185+59?>'F",HG;@B(E6<4B3+/':-.>A@A<""H-!!.G3%5:B3CE'B<G:F>3:!!B
@r8700
CTTATNGTNCGGNCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGC
+
&"(&&"'(("!(+'!"*'#(&("$"&**($#&(#"#$!$"((#'#%$"&)("&(!&!*(($!+")+*!%"&++(*+'&+(%*"&
@r8701
CTGCANNTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAG
+
EE'5#-$,@"HG(7E*;<+D;:63:-.<?=068-7;/$$0G(=*++C?G7#@;;6A!?!29%>2)H%66.'G1$>55@B,?#H!4",,:2CC%D82?CH8((<B=H<:<;""&2H60"34>:DA707,(0:!8>(=;'
@r8702
GCTGTCCATNNNTCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGA
+
$#$'$))#%!!#'(+$%)#"'#(+*+('$*#"!&)*(+!##+#+$#")*((%$#*'*&"$*&+(+!+$&+#)%*+)$#%)&*)")(&"++&')!$
@r8703
GCGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGAGTGACCGGCA
+
"D."F(=@%$,'G<?D4/'B+)(57;+=72A/E'.0/H.1$;2=;
@r8704
NNNNTNCAGNTTGNCNNACNNNGTGNCNTNNNTGCNNGNNNCCCTNCNCCNNACAGANNCNGTACNNTNNTCCACCTNCNTTANGTNNAGAGCCNAGGTGNCANNNTNNNTANCANTNNCNCCNTTACNATCTNANNNNGNNTCNNNNGNAATANTACTNTNATNNNT
+
$$!$!!#""##$$"""!#$$"#$#$!#"##$$$$$#$#$""""!!"!$##$"$"!!#!#$##"$###$$!!"!$$#$#$""!$!###$#"#$$#!$!"##!#$""!$$!$"$$$$!!!!###$#"##$#$$#$#!"!"!###$##$#$!""##!$"!!"#$$#!$"$!
@r8705
CTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACNCCCGCACTAT
+
&(<C27#--.7<E/0-,<:;B/-><:5,*:%%)GC3'2!6!D@@(/#/->78@"*F;(<-/
@r8706
TGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTT
+
1+!)8DEG#GDD=%.BB2H+#.;9;4.:3GGB":C=C:3=5H':E'9,'<3,C?(*B*.)#+""8CF'82,E'*<<B;@+6=)('/!?',=>//<G;G
@r8707
NACTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAANGCTATGATACTCG
+
"$')'#)''+'("%&'$)$##"''#(*"%'"$+&("(+&!*!)('("$&%*"(&!'+$!#'#($$&&
@r8708
CCACCGGTGNTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGNAATCCNCGGTCAGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCNCGGCGCGGTGT
+
AG!D!/'FAE=&;;-B(+:H7,5$@=*!5<;C)-A!/+B#'FF07*1'0)7#(<=/,!1:4&19G,=+;?>C%8C@!/F09'@82,=,-:%7)19/B09G*6!+*,C(7A>G3*A+B00FH'H*<%F3=-G8+9;@#-59<*,C);0
@r8709
ACTATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCA
+
($">9:?C*#C:A<,"0&=3BE/#F83>7C6=218GF6)6C>E0,CDB'9@%$38,99CG9HA>G'$G<7'C2HGB4AB7-GB3<1957-/-,4@HF#"81(%2'C!&A1$8)A+3.:"$62G,+,>9CA9E?+2:0?7<($1BC).7F=B.D34A56:B0-/53=8#0'-C?&!D8A0"8FD73,718EH&6!?G+HA#G39G2
@r8710
GGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCC
+
/?0H2,"E#=$/8H!@HH.F9#G&>A)'!=1)=;F</5+G7126H!44/0)"<6("7:C0!&7017<&52$*6
@r8711
GTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCNGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGC
+
3/*556*8$86;:/>,$D('"-96H%5F!'%H!<-1'"+0-%(/>H;E116,/D"+&!DE=.H""D.<<;CH$:C/C/E.E)$3=<,$G@6*!#A!$@58/8E#4*"/="7BC%C#)?/=6*46*:<8F(7,G<%*;!&8E!)+HB4;)'BFB0).1<:,G1(,06C,H(5?F78-0+,HB4+32,C6,6:&68:2%(>.;-6B2H?6&',=.
@r8712
CATNNNAAATTTTNNNNNGGGNNNCNTNANAAANCTGTCNNNCNNNNNNTCNGGANGAACANNCNTGGNTTNC
+
$"$#!!##$"$$#$!"!!"#$###"!$!#!"#$$#!!"!$!#"!"#$"#$$!#"#$!$"#$$!!"##$"!#!#
@r8713
TTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTTACACNCGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTNGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCNATCACC
+
+#?.8#02+,$D)1H6&;B253.+!>DAH?8(2@%9%FC.?=.B?@59?B,1C"7!$F').%=39#6%:AH(DBAG&D?3$F-*+"9?C'D.-H4HH83+FF-7)!$<'C:;<F>D=?8/4*F$*54C=>7/AC2..H*7')-@7.4E/A*2&!BB/GB*
@r8714
GAGGNCATCAAATTAAACCACACCTCTGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTCTCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCNACGAGGCTCTACCAATCGAGAGTGCGTNGCTTAACAAAANCGCAATGCTTGGAACTGAGNAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAG
+
$*()!+$%'&&(+*$$"(!"%$!#*(+%)("**(!#+%(&!*'&%$*'#"&)%'%!%$'$)$$!$'#*((#&*#!#$%"%+&&)$*'"%+$&()''$%!(""%&)$$&)!'++&"""*%)#!(#"+))('&#!%+)$!'$%%"#%&##*"##!"$*+$(%$)#*'&#*%!+%!#'+&&+%$$"*++*!+%')&#&)'+%(+++%#()$%*!"!$&$("&
@r8715
TGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCA
+
C6&0"@AACE5"-&6G$2;07A9.%''0<9'6*3/H.4>&;@E9/+8>/"6<-%657#?@+!0+);))8'.9@8+(2:$629A(CE+9#6@*5*0*D1)3!C5G(?.*="18!*#!.-B#1B+66.A4$=G+=7(G0%$,?;>!H5DF?!6,++/'!.$/H9=B7;602'2--+1D0?++@<),H"03E-1-H::>GE*!((9("A?7-
@r8716
TCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTAGGCGTTTTCATACATAAAATCCTGCNGGTCCCCTGCGT
+
E5A?)$G07B"%C6(.)+GHB1,7)%8<(B<>6G#.259?.+%5'+:,/D<.'F**#?/07+-;":@773%D(9*40+6!D8#A+3$H7B#3)8%$!D"60)!AC8&1);1:*-$090":"$&
@r8717
GGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCA
+
(6;.(B?#.7*!8194(%A$?$G<81E*AC5#1319%$E#-$!+5/*;#6+56
@r8718
NATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTN
+
%A$2B:72G+D,5DE58C633&%=$8G>"<GBC5)'4B%@ACG7A&'!C8AH7,4>,,>,!+=
@r8719
AACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCNGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCT
+
G&$.*2"#2-(,BG-!!B@"B>5<4-9-9,<2?<7B68+"#.B&*EF*-2;2&!""$,$?)3/B$10,C(C&(H621'*G.B>B3@<2)@4C0@>%!B)H3,F1-F05>6:F&((A=+B:9>:+1(3;8,F@%<@*!%"<4-@'1>*CGEA047"D6"C3AA6:13$&%%$60
@r8720
AATGCTGCCCTTNTTCAGGGCTTAATTTATAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCNAGTGGNATTTATGTCAACACCGCCAGAGANAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTATGTGAGAGATCTGAATTGCTATGTTTAGTGA
+
+$$$**$#"!*)!"*#("!+!+)"((#(#$+"'&&+*##'++%"($%+!#&))*$%#+"%!&*+%"%#*#&#'#'+)+"#$+'#")(*'**!%(&*("#&$!(!("*+&&%')"!'"!#"$&!)+*"&(*)*+'$"+%!)"'%'))%"($%')""#*$!$*%(&+"('&(!"%###*$$$$%+%!*)")&(*'*!##&)!$#'$$*'%++)&#!$+)&#"+&)
@r8721
CAGGANTANATGTATGAAGACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGNTTACCACGGCGGTGGCAGCGGATTTAGAGGGCAGTTGCGGTCGTGGAACCC
+
#&()(#&&%)*+*)&%))"($&)&"#*!)%!"(((#*$%#(""!"*)!%)!'&)$&#*%#"$#$('*(+"#&)&'%!)#&%+%))&")&))"$()("$)&'%)*)!&&$&%&)%"'')*'$+$"(%+)+!(*
@r8722
TAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGT
+
C=A?'@34A9;%G-;:*:+9-D8)6*223<7'8;EB'+>-:/(90:4(2&5*"*?!2C1.?8((&=2
@r8723
AATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCT
+
8%!-&F1F;->3:795&#*HAG+%/)"56?%<%?6.':22H3A0C;*GA11"%'*220ABC)5$>2A"5D64)<*,:FC,.C"4?<=,"ED.-0)C3HC6DB-%!
@r8724
TNAGNNNNCGTTNACNAGGNGCNNANAAAAGGTCNTCCAACGGTTGNATATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGG
+
&"$$$##!*%!*$*$%##%!(""#'"%)$''$%)!("'"%'(*'%%!%&+!#!+%%("#'+)!""#!+'+"+(()+#%*(#$"%$&!#""")$(($!"(
@r8725
TAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCA
+
!$0$509"51D3>!A$<=D5'4*<>5<5H!D(F860$9F22&'%;&5$6H45:%:99@ABG7A&B4)-.+%
@r8726
AATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCG
+
B."?.G!C(G>4<4A'"+'<2*)7&/0<3!<0A&A2&:8"<>*?7F--?2#/)D'B('3(1@/*!H
@r8727
GTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTTCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACG
+
8325H$DECF5G93,%-8@,")F1++CGG/%,F5B/C("&BB@2H17+A$<D!CD-%(E3**<-8B;-8?>::;*:5?8:0D8&G*HF@-0/0?&+-.'CBF+;@$:!5>H-G/C'A@$>*H&A)5<=8780>-<<=+=193G2$?/=9.<A%E=8,@C+)B,"##&;4!,<2,1=7GD:%)75)6$+=3.#+-6-.@.,)D6-34>4,21(23-&0(&+$*2#B04D0ACE+&*-.F,(7B"$6>6<A<'B+.E$%+#
@r8728
GAGCTGCTGCACCATATTNCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGACACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAANTGAGCG
+
0%G);C;>:.9D(<1(8/&H$4*>;!"!%0?$7DGFH$'=1!E((9:G&E63=8A4H(5@D$=H!&:41&!D$,$28-D+D%</8$F>%A(3<#."7'C28>;+-1?#>*,&#'1EC4-?)-,600'9F-<&G0$'.F/*'(=3%?:.;&08E>"%?(/826'CB"D3$$$D:%&=H.+<"5;#D.*56A9%0'721%-8?>/$0:B@;:6#''7DFBB9)9)7(
@r8729
TNAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCA
+
%"7:0)?>B((;&DB/$))96+@@G<85?-.(F;#/"1/$(E1-=F+>+49@H@#4></.*?'*/'?7%DA0':$!/4
@r8730
CAGGTGGAAGAGGGACTTGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTANCAACAGGAGTCATTATGACAAATACAGCAAAAAT
+
C:=!!,>.04<>5A8>C38"7FE.(6)E6A8F.?4@/10C*B84)/@G$>=7>A9G960G@:.G-=5$,/E>,D2@5C47)3%EF("5?D.)/@5@,9D!&+*A":2B%33023A@7<%3(@E&<E?2GF2?G%&8D%GE1+>?'>H1<C7*2"/$90*DC!!H5(F>(!#(A)E30!76H2'-1E(>(+/F96>".72+#BC5'D39"#BAA?/EC;F694&B
@r8731
CTGAAATGTAGTCGCGCTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCNCGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATT
+
;?5;5:<7@9.#918E)+)A<*+//B57C(4?A7,/,$!#39>/>#07:A)*;1<$CE6,13%4HG!G/2B&)'6EE#)#$F8C3;%,C+#?-(%B<C90?04BD*!;*-AH5DB$>.+
@r8732
CATTATTCTCCTGAAGATNATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAANGTTTCTGCGGCNTATCACAAAACGATTACTCCATAACAGGGACAGCAGG
+
&:=$<=2&%+#HA#B*1HB#:++6(B"-,A55=>;(9)<@A+G57+C'081@?>(DH>HC)-7$>*&10'D:-A<A9<.%>6";;0:($:FB'%'8,!&'=177>(03%$1-!6$:>9'%"/FD*9$0+5@$$B<B9/,
@r8733
TGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGN
+
).=(#::;&.D>G2@H<>;G/A>F=;BEC=!(4(5H6:&=7#E#9-96EC.2%7@)4-+/C?/96H89>#>'37",-="5'?.H$H9
@r8734
CCCTTCTGGGGCCGGACGGCAGGACATCGNTGCGCGAATATGCCGGTTATCACG
+
'3>78'9/5342)E!D"4A/7F&+4H-D8G38!%G15@=:C@*>.$:>F'>1*;
@r8735
CATTGCCCGTTACGGTCGTAATGTTACGAACATGGATGCCGTTG
+
%?*3+7)D>=H6?-5GC>,(&E,(,.2;-1.3&24+8"9;6BD!
@r8736
CAGCAACCGCAAGAATGCCAACTGCAGCACCGTCGGTGGTGCCATCCCACACAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGCGTCATTGCAGGCGCTTTCGCACTCAATNCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTNAGGGATGGGTAAAGGTTTCTTTGNTCGTCATAAACATCCCTTACACTGGTGTGTNCAGCAAATCGTTAANGGAATCAGATGCCGGGTTACCAGCACNCAGCGGTGCCGGTGCACCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTNCNGCGGCCAGGATGCGGCGGGCCGTNTTCACGGTCATACCGGGGGTTTCTGC
+
07;F#*+F?D3('(-8'('B/-<3-=A"E<*=,3/,;:<$C(4*1:;<4&H#G;15#2FE.#,,3>&9!A!#;'@5#E65@*4+>,%.,H8'E>,F2)?C791*29$*"*=8B;'=D@0#&>-:>"E71,==C4*B6E"5H52$AHFH'3&F##?*/;H94A0A5$-(0/+BDC/H.6?$(;"8,(")=",8/D=%5+*6BD9H%'B@9<<#3=DG82-:55!C*C0=5)5F,HC06$G:@A,*5#3C)((B,G',23D>2@;@F<)9-$'B$13=?%-F+!,'BG::CB$8-=1)>!>:4(3E;<>=8%&0E5><132:-C2.$5;-D50$4/HGA,B$D?A$37=()!.7C9B7>F7):HD$*#9;!><6'"+/GF#&?4;B>;(':
@r8737
TGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTA
+
'9-!647GE'+.C.*$A"!'3H;@;D+=/E:9,%(%+BC6A=:1>"
@r8738
TATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTNCTGAAATGTGATTTCTCNTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATNT
+
?,A.-+;7A)&B14-H#*HG0!*B;%4/G@";2@!4",**!-61**/?--GBF8E1>8>41B.;8#()5"'=.:>1!>&6?A@D86-<A,.G,(9F&F16/:4)G$DCB"G%F)>)?'*AA:!$
@r8739
ATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATNAAGCCAANTTAGAACTCGTCAGAATGAATAT
+
8=6+?1F1:8"2#AC??--14(8#/8@?+=#G457/0G86HHC99.B#4*G>D//$/,!"AG1$'A(/:(,8)8=3E2972D5B/E$0F);17=,:C)<<@84
@r8740
TAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAG
+
)A-$7G-%0%7*).84DE:H"=/B:>*E55.(83%0:4A$DFF.4+:$B+!&G%B?-4',C099'$=:6
@r8741
CAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCA
+
>*1C5ED#>GAB!CAD0BD97*@&):0/G$*6;575/'33>(4!6B.#>A"75DB/E(5.AC9>6#89E:)(?E>;;/6@99:E
@r8742
TCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTGTCGCTTATCTGCTTCNCATAGAGTCTTGCA
+
G4B4,B$-8,C@36FA84.-'%,B4;-7@(?F.D6AG&F,/7E#BGC0=@BC.;+><0;F#>-&92=+3((72#/-,/H+A5'/&-?==/8):"-%;
@r8743
NATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGG
+
!44C(B'(5%-.(=#G7#D0G&>E"+H?=C&5F;>>?C:.
@r8744
NNCATCNTGAATGATAATAANAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAACTATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATG
+
"&$((#*('+&('+#'*(+%%$)!)%"%(&*"'$$(&$*"++#"&$("+"$&")&#$"+*$&*%**+*&()+(+$$"'++!&+*'*!&+"!$(#'")*+'*(%(+!#*%(#"++!%$++%&&"#"&""$%+%('(%#)%%$+%)#*!"'%#!##%#)#&&)+!%$('()*)"+#"'$)"*#&!*%")$*!*!#)"*'*#'"#+)+&)#$*%)!*))))+%+%"*+$(&!!(((#"'!&+
@r8745
TCGTGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAG
+
,,+A6!-5!B4HB&,C7*)C1-D0&5#'FF75G";D9A,29C=,#C:0:$0!2.?<5<BF62F%&*C))(GF00/H3+/"1C"1G/4D9*2)"6'2==4=&"A?;+0-H6C<B>H.H&5H'=1*@!#D/G"H2&)48*.*1GC4(E=
@r8746
GTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTT
+
'<'?HB$.CH=0>&.?:G6(2%#.',*;F&%:+2D/AG@*+?51//&9/>/
@r8747
NAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGC
+
!29G=D>+@-0,0)C=!/$0@3:#)HF@<@=>:5(@?46%-&GAD"G=$?$CE+9);,B:1*G(<(;C?'H*&B9;*D=/C85*65"#>5@27E1CB1H+:F#955A0%97D$!91:0'=:F.EB)!,:>+87'#?;0*?8F(4=$F'9:;B$$=>+D)-B*#G)3$B#8-$0-$3*5<921,'E0.!0?<E63=$'.06:>(6=6,,FB35(@=#=*@1<,+5*?D%1F4'?59;@5C
@r8748
TATCTGATGGCCACGGGATCGGNGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGATTCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTAAACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGG
+
DC@%..0A=G00+1&1?H/@BB=30F=+3G16+<(2,*7-9:3=?8$#7&$B&CC+(5AH%!@,0;,$)<&:":;*-55<+,(%+7#A-;7.->&,AC<4)-?<3D%442<@A%":<6D5/AFBE"&D>>D63%8"-AA+.)&EC3=A:/:D"#:6);+E$578%54=$>A#7<#;(%,
@r8749
CANNGACTGCTGCTGCATTGAGGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGNGGCCATGCACGCCTTTANCGGTGAACTGTT
+
#!!%+$')$$*+'#'(#$'$&&%(!#*!'***(+%*#$!*+!*$)'+#+%!$('*$*("!#$)!%&"#*!$)'*"&%'!)+**!!)+*")!$%$)&
@r8750
ATAAGTGGACCCAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCNAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCNATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATC
+
0+B7E.0?>&/?,C2:2=D'$AF##G8!0"432"4)?(>=;%)C7.(1D1D(AC<A=3<)A:F.*('1$C;FE4.D?<85,+(=&'-@<."D,3C0C4??C*";A$;"0+E4=$9(613$9C2E5>1:D*/,<;1.85'-A$7-*3E0;-AF83$-*>98=:<:,8
@r8751
CAATCGAGTCAGTACCGATGTAGCCGATNAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAG
+
;-B$6,%=>.>7HA/%8G-/=F4.)%?+"%%0#%/@=:91?D?F!@&8+G$?A(8@+0*=4=$+A%5)C'-GF3/>!$.
@r8752
TACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGA
+
18@4H&29&,#.44GH:@DBB;0'B-8/;BH;A7>C32B///-;5'G#??,:BBA,#-1B1
@r8753
AACTGGATTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCA
+
-HC/4+23..D=0"31)17EG(":8/EA/"?74F3#AB=8<-5AH)',G$'0@;(9GA&AG53<
@r8754
TGTGCNGGATACCGAGGCTGCAGTGTACATCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGC
+
+$>B9</2-212)/9;7FC+-@,&(<5A/5'/@A:B,7C',$,?%0-?3&63D!3G/H<'#7,B%9/==G:0==A)EHD.C)+BA;#
@r8755
ACNNGNNATGANAGCCAGCTGCTTTTTGTTGACCTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAA
+
("##%!$%'("+)&#*"&*$"(""$!"*&'!("+(!+)&')%"#*!(&*&&$+"&++*&$&%&")!(%#)&()'!*)'*(#!'+*#!)%
@r8756
NNTTANGANNGTCTNCTGCTTGATTCCTCTGCTGGCCAGGATTTTTCCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGAT
+
)"')###)!!'+!(!%*&"#"("'%!&&&&%"%#'*"%**%$#'))%%*&)"*)$'))*$%*'&!("!%#!'*'!%(##&)*(+"$'$*$+!'*('
@r8757
AAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTAC
+
$+>16D(*E,8'CG5.,A/6?;(8BEDF#6BA<377F"@0"H6D,1A#,9E;>C-0"*)A"3,7FG(7G99.+H$F80DD
@r8758
ANNGCGGCNGANGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTTATGTCAGAGCAGAAAAAGACCTGGGCGGCTGA
+
)"!($)"*#*$#+%"*)'*($!&&"($%&#(*)$**&*!+&'&'!'*"!!**("+$*"#($%&%+##!)%**$#%(%(##'&#!
@r8759
NTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTANTGCTGGTTTCTTTCCCGTTNATCCAGCAGTTCCANCACAATCGATGGNNTTACCAATTCATGGAAAAGGTCTGCGTCNAATCCCCAGTCGTC
+
!+"%"!$*'&(")+"#&!&%'%'(*"&!(&(!$+**+*!##%)!+"'%+*)))+*')*($!'&*'"&)'$#!(*%)!!&'%")$#'&'%"*#!'##(&"(+$'(+!+&#*!&+%'('%"$%(&)*'!'#$&+"*'"#+'##$##*("&!(%*$"!#(+&$$"(&+'(#!
@r8760
CCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCAT
+
$>*)9<=BB+:3D;9A;78ADEB4BB7@-BH8?H">?2=9?&%/<%5+H?),&9$=-=,55#/H:(?F;
@r8761
AGCAGNTTTGTGGNTTTACGNTCGNGCACTTGAATCTGTGGTTCATTACGTCTTAACTCTT
+
#'$$("*&!%($!!#!*"!&#'(*!#))$*(&**'&&+$#***%'&%'"(&!&+*"'("&%
@r8762
TGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGAT
+
G&H:B=9A>>%"%BH:<=,#4$7'8#";"2CG#5?)6+//'&F.--8>F+.C()"9':$'G,4#$
@r8763
ACATTAAGTTATGACGAAGAAGAACGGAAACTCCTTAAATCGGAAAATTTTCATAAATAGCGAAAACCCGCG
+
52?G-2;F!)<.:#1%;)@$?>#/C+,B="803'ED059)$F.A/&,.:6$DE+-=%?D+#"AC(5)9A2:$
@r8764
CGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGG
+
E=8%!/-3FE!'<$&BD$AA"#,CD+D1:9E&!#?,($F%$>C
@r8765
ATACATAACGAAAAACGCCTCGAGTGAAGCGTNATTGGTANGCGGTANAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATNCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCC
+
5B%H2.;9<$"G@8%"(>5'F#9'7+3?1&@4<1=/='&C"2-<86(5(,C6=5"7A(9D%C!H6++/C19D)2#2H;7,=>),!.96A<6-<-2@7#,418?#3!>7E!."#;6;%!"F:'90B,D5A>@(*9%-9&C$:+3D$4:FB<=,C52"-*)@H4#8+:<HE(EE2")/EB
@r8766
CGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTA
+
.E@<86>0*4>%3G30BD.,F@C)>65?(0=)%/&$@><"DF?HE3+&DA89GG"E8C=15&:8@G*.6*.EDCF62;>>)H2@,7624(>ED+'E+&135"%H&1@"-3/37H':-9GE,4#G%F#E&GAE#:(5"G0
@r8767
NGTTNATTTCGAGTTGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACNCATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGCTATCGTTAGCCCACCCAGCAAAATTCGNTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGC
+
&&%%$&+#!*'*#$)('#''((*+##%&$$$+))&!#"'+$"(#&*'$!'&#&+#(++#%#%+!!#+!&'"#$&$*%&*#$(++&%'##%*!#&)#'&#'('#*!(+"+&'"#%&%$()%'($')""!()!*$(#%(%*++$('")$#($("$(#)!)'&!%$(%##$)#!"#*&'***&(!''#!($!#*#'#($!'(#%')")+!&"*!+""*'!%&+$$$%"$
@r8768
AACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGNCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGGAAAGNCCGAATTCTCACCGGCCGGCGTGGNTCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCC
+
;=CE9*?C85(0A2-EG<3F,)D8E(=HA15?G%4-(8=GC*C$#?,/E140.4@GB"/)*/!>*D6".$*9>%:1<A)*0HGC2$?D)<C#H4-81E41C*@""33#G&0!-14"(':C+:F:,G6:D>:G8GC4.E9F;'3,;@'D65"145)&D14084%<D)B7921$3##!BF?<>@H0DG"+67/A*F"(,,8;?9,:/A;%>%)(84?7!,&G7+:8D4:8,(:5>
@r8769
NTGTNTCTGTGCTGGCTGGAAGANGCCATNGTTCGCCGCGTGGTGACGTTACCTNCAAAAGCGCG
+
0F,)0@AAD7,&<.+$:$C2#<--E59?H$%D34=4A&@'-A,?A'(5<F*7.&2/A9*#!*7#A
@r8770
TNGTGCTNGCGNNNGAATCGCTTATNGTGTNTGTGGNATGGGATTTACTGC
+
%$*((*$#*&'!!#(('#'*")#'(!!%#)#$$&*%"&+'%)+%%%!)%*"
@r8771
NGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATTATCATTATCACTTTACGGGTCTTTTCCG
+
$+D*.*2*H#"/.-3GB<&BD30?404*C>)D")"6-/43#(8';7+>3;>)'*H#(+$D'(&"-!8HA87:16=FC%"3780DH$,9<9'170(=<<97F@A"<?>#??:B>G>3&
@r8772
ATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATNAGTCAAAATAAAATCATTATTNGATTTC
+
@!E=EAH>E#+<'EH)72%?7+E'@,3;7H.+8=B/39B539+G!;B8.7,259+DC@):1$<#/6
@r8773
AGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCNGGAATA
+
F%?-#8DB&68*>,(.$1C@5+G5##1G0%&$9!CB8A)$"
@r8774
GTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAG
+
<,-/"#6@-9)<-&,H#106,B9D>/A>E8F2/#7,1AA?(**"8+@#%*;92!)87FG3;)>8F>FE125H>(4?H%0=E<188+27&0F%<C?'1G"/<18+
@r8775
TGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGNCAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAGTTACAGCGCCATC
+
-0'!=.3'<08/<G!7-/&!;''(,@;.6/=A0GH8B8A<<=+'8D5(89=("'#H->FB(H>.!,2=@3F%9C.0<B(<B0+9$+@!G'&!$#*>8/%,;8HF4=6(0%F2:$6-5/''DED80(1(-H0G-!A/G9GD25.7=.)&7(>#21*%>DA?(*/
@r8776
GGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGA
+
C+@"=;"("C-H?8#4?7$F%&#C&B=(9<)0;C1&5*#?)-'55F%(-%,D4$!21D-8@=-6D@4G(0(%$-*6@?-B-(H!7G$)8+#H7$!$/"+."A?."B$*B5.6,(G+##9HC:'>=?1/G96#@*:4F@H=(8>5.@=4DE0G(#8;<C=G;,'4+D*5+(0D5/-*<%EC/EA38;+.>F3$<(H<H-2CH*;/*?H+'D9D!2)-4,A,;A:!8:F/6"EC"C/G16A#2!B4#$A6:@(0-=$96<>7H5-?4HF*+/
@r8777
CNGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGC
+
$"@C0='AG;126)C-%'6$+735HAC*A1A(B,@,49F"!)A2,AG*71<G2
@r8778
NCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGACTTAATTCCATCCT
+
,>2C;'+:.+<=0=7/@!A9+4@*E9270#-FC@;/!=>'(-$2=2G$"*D-08AF
@r8779
CCCCTGTTGCAGNAGGATCAGCCACGGACTTTGCCCGCCTGCAANCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGC
+
302&?183E/9&9D#@B1<E&3E4C;@+(<;78C6;&GC*1?2!HCB?*;-@A%!*F!79BB*/#4%3;=##5DA170%G+;.H(9=4-)BHF.80.,/70$7
@r8780
NATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACACATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAAC
+
,)762"%!-)$G1?0:*F*">A%D$B@':!C&BG+!&;(9/>62A"9>71HB4CBD)+:8#4E$#>C>C4>2)<@&5+A*D"9(<8@GCA0G16#"*";:3$
@r8781
NANNATGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGAT
+
"!*('+)($$%!)+#$&%%&"(%#)(((#$!$(*$&$)#"()+!#'*%%'(%"*!&*'(#(
@r8782
TGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCTTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATT
+
H'77@!2#":'A)/+$,>("8-G$7/G!,+8/)?AB&)71"9CCB8"50,.B@==AE@/49GA28.H&F*A='@8<H&.#6B59B3CG,9):E=0.'?'6<BA;F(A-:#&!1?:1F5=*E!5673A6:540??379-E#,1@4&-*)<D#>!B629.$(F%A9E";;HC+!<+E@33;0$9CCH->3>3(".41;-*A@146%67B$5@?)81,A@%53B&F%5:$;($><+E9;36C,9#,D:*H!*:11<6-4GF*,"C%C<$
@r8783
ACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAGTAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACNACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATT
+
B=BAH@(DG"4&#FE773H;DF(:@/B0823+8D(.C0(38"829A0#7:&93$2A8.?4+259+/0;="8%8,94/%8<"7;8C(B$:/"49A.6)3=:/,:'HC9#+,(?BE9:;#$%C<$B8)AE16<$G9/'H.!B-D"!53#;7;EGDFH=@6CG<B%D;8)4H.;664;54F+<'G.?8>1"1'=(HH0@%+2?<*<4@4;/&8#$"
@r8784
NCACGCTGACCGGATTNCCACTTCCGTCAACCAGGCTTAGCAGCGCGGTACCGGAGGATGGCAGCGTGATTTNACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACNCGACCACCGGTGCTGATACCGGCATAGTCATCA
+
"5,F*F34ADGC:<*F=G>/@3F2:;@=B*.:8:6/5?G@//.)H,33).2%8#'A#.,*/7>26@C5(>E/;(AG3*-(:.6?1/BF58/#G%=!/=)>%E+?,H--8%EA'C'C43*.+D+H,*8H0'+1"),3?8AD//<&>:5A0+3F
@r8785
TAGGATTTGGTAAAGCCGGCCAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGG
+
G9D9FFD2E:FBG$/@AD'7H$?H9%2,B7E43)7F(,?:C,/.G16:"G5/7>1$,26),4A",!G%*)GG;2>-2/B:@EEF.B'C574@AA"&,'>$G2DF!@7$0%$8?<G;$ED;
@r8786
GCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTACGC
+
@;',&8C=B$/*&C$B)A"?G-1'2(&,B(0/5#9,EF1@;F/+.:E6;-:=)<21!4B#D.F1E9>)E*$>/H%"CA02:DF9E*5!,:@)'*A78"57C%E>G<3*HG.
@r8787
ATGCTTCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGT
+
CFD@*:E*)218=2+3B0#%>>?G;)=%1+=EAE;<-C,=B,)EH>*!,-,=*321GD',GE!64H:=F"./.;G/%>:/6#<6?;$"H=+C(?H.(D5?B*,;%97*$.%;+H$,*FCF%#G7B!*#7(+"C!:6>"')'F/-,!G680"7G%)
@r8788
GGTTTGTNAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGNTATCAACCCGGAG
+
AE<:>;<G.C#2*500E2/@?!+8712<',<B@@7=?>;*7.24%'HC7D7;++&9D;%=:9A./6/+AD%
@r8789
GCGCGGCCTGGCCAGAATNCAATAACGGGAGCCGCTGTGGCTGATTTCGATAAC
+
#$2.80%H&>F/@!%0',H)1&<86<+D93$C+58:,3$-78G0!+)*H':&F#
@r8790
CGAATGTCTCAATATCCGGACGGATANTATTTATTGCTTC
+
:#+@3.CE<%2!"G3/?,2E90E3:16F*0&D5;5",68!
@r8791
NCNGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGNTTGTGTCCTGAAAATAACTCAATNTTGGCNTGTAT
+
#$!678#%#53EA8H#(287>=7D-99?H4AA425D2$3#',7C1?1184:9G-*$G/$D!8*6:4+/7=0.:?$*@?B2'%C'(@$#%-H)F2-H)%)!-$G=4)F"?1.&+':".9""-%+!;8+2H$,GF.<%/:&)GH=7*H">.8)H79@.,)C!.HHC<A7C;B64/3?;1F/B05F914*3;+E8,-
@r8792
GGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGTATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGTGGCAACCAGCCGTATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGNTTAGCAACGACGGCACGAACGG
+
*E/<:0:?:$>+=05CB<)!1#!@<!>D/.@7&C=53"&";0AD9%??(43HA*F:B<:*9#5:)9>/>-&"A0!DA1&@;+5/$*?A),@.5$.BC<"62GH.5031>(2(#9=(CAF9&C.E*3:'6$";D3G&@41-+$0B="07$F!D0(5E39@7<&4+C)@:$:G:'(!.CFB!>*=$7)B+F#>-!C<>&E$AF5$6C"$6,2$!13!?822!&=HA,2.EA2>A83#E*)/=;6
@r8793
CTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTG
+
%0C;#DG(<0G3#4"AH'.C,$E.8>?4+E5*C9EB+(()-/')%=:D+(?C9?'5F#3
@r8794
ACCATTGCGTGAATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGANGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGAC
+
+!***!#(#!###+)"%!%+)+*$&#")%**"#+*!%&#))++&$)(%*&'%!*(&%'')"%)&$*+%+($%'#+$'#$++##*$%$$&)#&&!+'')"#
@r8795
NCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATNCCTTTTAAATTTTGGCTTAATGNCTATATCCAATGAGTCAAAAAGCTACCCTTN
+
'(%"%$"+"(#!&$"#&*%%$)$)*"(!#!+!+$&#*#$#)($+(**+*$'%'#&!!"()%#+'&&!"$!)!!($")%%+(#'+*!'"%'""*)$#"%#!+((#!)&)"!
@r8796
AANNCNNNNGCACCGNGNGNCCGGCCNTNCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGC
+
*%"!$!()")$*%#*"'"*')!$#(*(#%+$(&'$!)&'+)")"($%%%*'&((#&$(+#"++$%#
@r8797
CCGGNCACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCNGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCNCCT
+
3"=,E9='3"5!F8;/,C<F%A*4=";/-;B69)'74E-?86+,?)-!'A1/(DC>-$1'5D0(*(/6D""B8&:26G#3E4!11HE:@(0DE8G&:,98@;=5@+*+!+;>"+>:A>')&9;';;@/A(8&/1H0/#C$5H=).)"(F+&B-/&A>"14CF!H7C#:BB$D7+9::01@41"$8#)<C6+G1>@+>+7H*HD'765=,!-9.)&%<*C;)E&B)7B-<0#2"/9":;('5'=930#B1G-#"-;89"5/!0@&74##"H"1@/D2(0
@r8798
ATCATCGANCTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGAGTATCCCTTTGACGAATACG
+
%+!$%*)+&"#"(')%"))*()#%+(')#%*#$($'''*+"%*+*)'(***'+%$%'+)&)''$+!)*))
@r8799
AGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGCATGCAGGTGAGTATNTGCATATGATGTCTGACGCTGGCATTCGCAT
+
E#+.C+(D'!D989#E"@;E>2#H"!'HCDF4?H=#E&HDD(!==?!(&7"43!A2B%,1@#H>4;!3B%:@/DD#%DG3!;:12/4/#3A.;@.GG8.7>H1EB%CD87!)-1-3*('D#A3',2&
@r8800
AACATTNGNAAANANTNCCTNCCCAACAGCNTTGCATATTGATGCTCTCGGA
+
##$)'*)(%'(''*#$%$&"$+#&")*'#$&*)!)*&)#%*&!#%&*"")&)
@r8801
ACACCGAAGGTGGTGAAGGGCGTGNGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGT
+
F=A-2,>(5$&=!*"!38.71E864!*8.4D(3D2!"G/@-G%F03>;*6;'D!@85-E#($7;)066@;H0,G:<F8;$0H?!-!!A/"1&FA!5B#/+-%'!@"E2B=>,(-:H6#EAB-!>,4/4F-6A9E%<G;447E+$E0G?E
@r8802
CNNCGTCTGNCTGTNATGGGCTGTTAATCATTACCGTGATAACTCCATTACCTACNAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGAGGCAATTACTGACANNCAGATGCGTCAG
+
*%##+((&'"+'#$(+)++"))(#+*+$($!*"&!'("&)'!!%("#+)('!'+"')"#(++#&!"*%)+))&+*#+$$*%+&$(+"&($!*&(#$#(%)!&"!&((&&"%&'!#%!+(!#$"##&++&+
@r8803
GGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGG
+
24?B="/1@0##,3E$66-HH7?EA3!?79?:::<(43+49C
@r8804
NTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGNAAAACNCCCTTCGCAGCATT
+
('@+-F+)F..'@C8%/#+%A-HC?C?#A7+GF<HF(>>H'D43+#;?6<)>#/2(*E
@r8805
GACANGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCGGCGCGTTCAGG
+
,1F*GF$;'B2$=7>=1)?F2*&%,&8').7.0H;0/(G#&(@$=1(-'-=9A7(:#A(F+;C8F(C;7'."%'GG+-"?&;8,9(-()#:*.$.10*-F,A=,2840-/B(:#$,@-55C&C<,03A6"3/C+):G3<H7G30759$87(28!A/6A4!='"892:BAD.B#9;"5
@r8806
TTCATACAGAAAGATTTGATGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGNGGATCTGATTCGCGTAAAAAATATG
+
A2D;/);100<=#<+H<H=A8F89G%>0G-*!/'26:1AE"D$$'"E+,A0G;/C@F-(<CD'77FC.'62+?"780"$H7*H''0C$,!8":1%A!*4H0BG4"%&07;/,<-'6+G!*=D0)F.F
@r8807
GAAGCCAAGCTACCTGTATTTGGCCATATATTGAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGAT
+
:):B!&>)E@;8:=-A61@622'B!:4H<C%8;B%B=;F0&1C+?4-?H35,)88482"@C>6+7-@6<9HD?;A1+$2-#EH43D'$</#*$%"0G@!%902,&7.26/"1-FE76:A!"CC9?9G8@<"&9/7$D'0((<6E'<!<<4>CBD<">;:"4E;!?='E3020:(G'=*#G$@<5,<(?B
@r8808
NAATAAGAGTAGCCTTTGCCTCGCTNTACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGACTTTTNAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGANTAATAAA
+
!0::G<!:8.:?&',B#5%CA.A6A"*9@.#$3-:"=2E7B//B8B1/#,/#C,8HE=/FB7*ACC00E/%.<!'=7#>!5<=%1$,#>'+,E83G!&))!D90A+;83G:"'/(1-,9>;5!"D(3;@@D684"6.AF1A(,(#&720+A&BD4GD#9)9.2"":)*1E1:!D;
@r8809
CAGCANACACATGTCGCGGTGGTTACGTCCGTCACATTCACGCATCAGGCGGATATCG
+
9-();A0&$:E6$%;;:GC&68H52A)!#8FG;7C8'&+E0.+"4C2G4/<C":<*DC
@r8810
ACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCNAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTC
+
+0(EB<42$0$<E!$#,')3>61&59=@/2@6'#$E$HB3?C@,,?!4@.4.&9;51'B8)0:<;)D<G>?436/=B"6DD$68$+;CBA-!+>6(&6%G2H)@.#*FA"+B:'D9(A/
@r8811
NCNTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAG
+
&A:%CBC"$2A#*C*B8)0$3<C>9A3E:0?3>DE".7$'4$.*+-+=>#&BA1?G>C%H(@>+
@r8812
GTAAACAACCGAAGAATGCGACACTGACGGCGCTGNCAGGGTCAAGACTCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCG
+
>:;1F3A)<2>!D>7&/@)AA8.&2/)H#D:E%C$54"7**'9G6&FC+BF=>//%&%<8):62,@/9#9:F$F,?-3(9HD)!10;EF,"$4D-!(/2E.G3?3D;"!#+GF<C?5?$+$0E.(*9)G9#E-EB%+F@&4D6=>38@9-E,+148$1&%A'<FBCE&?"%?82#.?1-8$'H&G1H<+</
@r8813
GCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACNCCGAGC
+
B@D"$A'6+3/"-2D,CB#%*GH(+A/7$$3)/-*7G7/C&9**5*='1)>F%&&#401&><=>(&13<HB%BFB0>4?CBC$G;!288A(8+#2B<B:0&1>+@(;@BE4'$B>
@r8814
TAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGA
+
4?83-EB,DB-,E@%+H</C-BE69>(<!1!&#%89#:**<H;$'=$9:%6,79
@r8815
CGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGNGAGCGGAGACGGGCAATCAGTTCATCTNTCGTCATGGACTCCTCCACAGAGAGACAACGGCCCCGAAGGGCCATGATTACGCCAGTTGTNCGGANACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGC
+
#B$57<@.'>:-@,+A4H+/@902--,$(HGA(.-!<5'DG&8((CF#5F:'6ED$9F8288!=1$A%!B@31'!;:8!B80A:$@+@24D'+=".01*&#%3+;G6@@)H+BE@.E!)D0G1A?/.C$+A'4'645539AA%>39#7=?;9A'1=)-CFBD))6077+F;8;F7
@r8816
CTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGG
+
!G(F34B;+:E*5G'=7!0<BD5%@?21/,2)#0$4/7=)E!5B$%?4GE-:7A9:*9G#/F4($3/!@&*9:B2F
@r8817
GTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTNAATT
+
'0#7'57<#5"5F%3#(0">3$80?<8-=7),/=<39'@*H9:&27C#:)!7E@$/GE33=-:7+1&>7FC/D"@F9FD7GE1@"
@r8818
AATGAATTCTAAGCGGAGATCGNCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGG
+
<H.1"D8;/*$4>"3+@#=D+01(C;+58<$;7%%$6":.-@-58).)6C;?0/6.<0)/'F(F4-@7<D03DE7H;6>;9&2&F%.)HB(.*7
@r8819
CTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTC
+
+'%+*!#'##'%)"!(##"++&%)"$#!('$*+*!!+!$'"#"
@r8820
CGCGGTGGCGACTATCAGGAAATTTTTGCCCAGCATGTCCGTGAAACGATGGAGCGCCGNG
+
552D&;@DB73B)32F>##EC)61;&*F1"&6#!3F#;#-7851G!9BG-!D916.D&(,C
@r8821
ATCAAAAGCAGCAAGTTCATCATAACGCGCCACATCCACCGACTNTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACTGGGCCAGCGCCAGCAGCGACGGA
+
=D4B<<0+,;.@:*8&G?6EB3H.8(*9;835(C+>-H"/35,<FG=D$;7@.#,*83C4*,7AG((BDB@C=G4F<,-E$H#"H9A?>+GF8,2>B-2D?"E;@.4*&;9.=?)1H121.E';->A,5&"E&&/7F'AG928@B2F0$<:6+F8&.B-;(5=<H,17=!(GA3?
@r8822
TACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGATAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGATTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGN
+
,D.!;A/.HFG,$?<9979:.C-(C-2=5!53FC(/HB:(H&=:G4A-%;3H09.8%&33B,G(@A20D$C"?HD3BG"!(1B%GB$6?4A7C',1);-.85@('H58>1?F"?D01'31/#%43#@GG)@!02;:.G'E=G<=C$7((HB5?H?
@r8823
TNACCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCGTCGCCAGAGCCTGTGCACGATTT
+
$&%&+%*+'$%"#'*&)%+%!'"%&)"'(*%('''!')"*+%!%"!&$#%('!''(!&&$)#'"'"**%+#+)+)#*#)!$
@r8824
CAANCTNNAGCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTGTTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCNCATTGNCGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATNTTNAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGGAGCATNAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACA
+
*%)%"$"*)#+$+'!!#'"*!$%'*'()'")'$)$+$!*%%)*"))&+')!+$%+&$$%"'"%'&*#)*+$&*$('!($%$++'$!)&)'**+(!$$$)($(!*!&"+&'%&#&**++#)*$!*&$''*(''!(''%+$"%%(##&+**+!"*&"#&'""+"+&+'$#*%!+#*()*+)*)'*%"'%&#+&&'&$*(+()'&(&%('!+(%!$"&#(!##%)%*!%"$!##(&")''!&'!(#&#%!#!'(%+&#"(&))*+&('&'##"*)&!&*%()""$**%#$(&#'%&"#!&"*"%!("**)+!*)'$+*%)*&"'$&&'&#
@r8825
TCATCCATTACCACCTTAACCGCCTTTGGCGTTGTAGCAAGCGTTTCAGACGTGCTGTT
+
>F+%0*++B#1D:CAA6//F@G','77(B83H'1D?>%1'5::61'4F8+0,06B-/'A
@r8826
CNCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAANCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGNGAAACCACGCGTGACCTCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCNCTGGGCAACCATGTTATCCAGTGAGGTG
+
*)+#%+)%+*)"*+$*"!#$'"%+'+'(#%(#)&"!)(+*')*'+$)(&&#*"(&&#&*!+)$'($!!%&'#"*)(+*$#%#+*+%#%+'$(%(++#%)#+((*!"#!##'#)'$+"%&#!'+)(%(*#!+'%''&)')$!'''('$$&!"($#$'")$((%+'$'&(+*'$'(!'+"*!%+%"#(*#$(***&#)""(!!%(!'#!"$'#))"($!&%!!$#(&&$(#"(+)''"#
@r8827
NGNTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACCGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCNCATTGCGTCGCTTTTTGCTGTCCCAC
+
%24(,+-+4"BC6FG"/D7*"<?@.DCC1**4=3*!9-,7?4(5#")C2?>".3&E<F#);D&-*3'$8B4?FH:4>*<"1$'7E@GF=@(#84$H9+F'8""$9-@32E'6&B+#
@r8828
NATGGGTTCAGGATGCAGGTGAGTANCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCNGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCA
+
%6#5=F,D5H4,/6;%7B?09+"8C2G/A**C.D/<-&A;F+GG!"/2C0E%28C..=@+39>4D'D8B?;75)F?91#,4/>)@&B5"57=%0=%F<!FCD4&%5'+!5/:AB/C&<;>0-<6H.%.=##&.@6.-G"3G+-!73>@-*E>&
@r8829
ATACTTTTTATATGAGGAGGGCTGTTTTTACANAATCCGGTACTAACTTGCTAACC
+
2A2-=?:!C(E3G&H"=+!'?/?$+>@)(@15>@):8/D:&6,H>*,:>A@1>/0E
@r8830
GGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGT
+
%;DC06-G>52C*82EG)/"(+DA2.#BA!90E-DAD#H-6E95CBH1(BEF'A=:8H0"":0,
@r8831
AGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTNTGTATTTNGGGAGCAATGGCGATGACGCATCCTNACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGGCTTTCTNTTATCCGAAATCCACTGAAAGCACAGCGGCTGGC
+
$'*'!'+++)"%$#+$#'"$!&$('+*"*!%%$($$%%%%'%)"&(#$$&*&$)%!$(+!)#)!+!'(%$'#!##!%)#"&(*!+&+%)$!"(!'+!$")*)#))!+*%%)%"!)$'(#%"'#&(!&"+*'#"*!*(&"'")+'&!#))(*+(!'#("$*++"&'&%#*'%$$')"'#(($)**()%!!$"+)#)''&!#%"#*$%&&&+($!")%"+*!##'$'#'*!!"+*'
@r8832
GAGTGANGCCCTNCNCCGGCTGCAGGTGCGGNGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGT
+
&*'*''"$%(%(#(%$)*+$"("('#''!&(%)%!")#&$#%)&")$($")"()+!#&%"%+#+)%)"('+"*%*!$*$*#+"#+%*
@r8833
ATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATNAAACCCAATATTACATAACAATCCTCCCACTCGCGGGGATTTATTTNATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCAGAATGGAGAGCCATT
+
-3BH>*<%FF?2-212">;F;7G"?<9/+7F@&</=>-EE/A84;:1;33)4-C5?$%(:32F=C#@79<<89<%%<'ED+;5.::7@0D-4"3*%)",A6F45E#-&;$8E8G>&/@7=(C,!8(,-#&$'&.>=%B;7-CEHA)A5,7%G=#/.8?.-)50+G7+(=4/5$B?80"@6".&*
@r8834
NAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCNAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCCACTGCTGCCGGTTTGTTTTGAACAGTAAACGTTTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGNAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCC
+
!D#>409#DG:)&(:G6@-#.*=EE#>%:+$66.GF356)?$:'/"E%D=#D9D263(C'=.>?"D5>;<9;?A%-#F'7F:!09E,).?<?0F=E;H23221#+HG#&@4"'+&'"3?77.%+');@(C./H3+325$GF335&<@'%2:B@)338;#$./925$G/%F;45&":-"C@!(-
@r8835
AGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAA
+
-G(<646C"!?3-G9CF8:,%+2894D-!70D6<3@<4@)>F>0--!7+<C)#B&BFD34>#4@+G4"57%E2H2B
@r8836
ATNNGNAAATNCCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGAATTGCCTGCAAAGATGAG
+
$"$"$!&+(++"&'%$)+%"%(#)$&'#!%"%&+#(!%'(#)))&"'$(*&%!"')***$((!$&)"(++*)"##)$'%"'!%#)(
@r8837
CCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCNAGAA
+
"')??-A8=>:>")7,,HF33@5$0@#BD%H@7?;@/;B.B.&5;+7A.D)7"E*3*.5@'.'.C08-EF7E!,%@%7#%.&E5;//%#=+-%%E;4=,'
@r8838
TAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCNCGCCAGTATCCCAGCAGATAGGGGATATCGACATTTCTGCACCATTCCGGCGGGTA
+
D,G?*3A"#';3+50=16&&=/((FA6=11$915G2>B#**H?3HC9EA=A!<57H2F2<$G(*'4H5B?;<&93BC0E"C/(/5!9H8C4H#-D1C()4$?'?7<H8)D@09"1G177-#(
@r8839
TCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAG
+
$!'9$!8;-@0&.!+@4(>.,*5:=6-4A.D/3?$@)7.?H%9(;#'$--@74<&+'B;3BE@GC;=,-=/$./,4'>3:E>D');60>.G0#
@r8840
AAATCTGACAATTCTGGCAAACCATTTAACACACGTNCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAA
+
"6-"?#*C(8=.:7-19C:EB+8H4A"*-)G5#3=?=8'?H%'?6#!=/,%B@4G8B$F))C<G8H=,$5+.8"H9
@r8841
TTTCACTCCANCCGCGATGATCCANGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTC
+
'+>+#2"BGE4-&%D5!3+45H##!11:D%+""$6B&4=88'B0%'-.%!''5#*68,?<-
@r8842
TTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATAGGGGGCAGCCATTGGGGCCGGTGGTATGA
+
3H8#%F1F4,0*E?F,F3GD5H15AB6$+%?-75#@!?0E7F1+(4?/D68?:H6:"(>BGD/;C<)%F'B5
@r8843
TCAGTTGTCTGAGATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTNAGTCGGTATT
+
$!$$)%%*%%&%&#+("!+&)"#+%"+%$#*)))*$((")+)+#"&))++%*'##**+%"!(()##%+&!)#)#&)#+%(%"*%#*)%'"##
@r8844
CGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCNCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATC
+
037B.5=)4#&&F/G2B$6D:8+B2H9EG&0$(C(F$<C@17#%87%EFG6:<A7<C(G..%/$8!C&21B$B-AF
@r8845
GTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCT
+
.4!%3"@=5B/:;(@F385C>!0E)@E/2BC8HC-7B>31$@!"!.2A)??',<?68C:%4;,'2E3:F6<G0-B+A'F#*CH#;"B!E'E2H..(:/8'?%9!74,@#HD63F?4)#'D@)1%<.7/8)-E)2/F54-0E9(2H7$AF)E!$@%!$:,.6H%9#H:C3%(1HF
@r8846
NACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGANTACCTACGAGANAGAGTGCGCAAAACGNGGTGANGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCCCGCCCG
+
$.8C-C!#/+84<%D'A2BEF'3.EE'$:9)2)4,-55DB5>.6%'@.2$0D29$,5E/A0A17D2(0*8$E+$/-1'4*,B#@-38A&G4-=/8@*9>;:5!6G9$A?EGC?(.,;&C+7&/G/#5>?H&)D7'EF<A=;<!:!B6!(:9,!+5;A8$%@7+@;(1DEGE6-9+/(+>1;8F!7HCG@11
@r8847
NGTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACNCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGNTGCCG
+
"*G$A;!/109AB)$H3!A/?0+9)H1=*-628/*E?C!6"2-".'@22F:A%*;B7,<G!97:78"&66@/$7@E8F.C8!;7#6??6<C.9&4G%;="*<<AB#11C@%",8D3)FE(;0E'7<<9*,A+"%.BE:=19E.HB'+2./69F
@r8848
TGAANNNCGTGCCAGTCGGCATACTCCGTGGATGACATNCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAANCTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGC
+
*$*)%'"$&+('')$)(#%!#$("+$)&##$'&&"))#!*!%((!'+''&!!)"&&&""%#&*%+*"*+#+#%&!+"&$*!)'"+'#"#&"#$+"'%(!&&%&'(!*'+)##)***(!%**")*&*!(!&"*'%'(+%%+*)$%$'
@r8849
NGGACGTGAACGCGTAGATCACCGCAGCGGTTGCGGCAGAAAACAGCGGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCA
+
"(+*)##*!$""!""**#*'*&""'!!##'$&#*'+'&'("$($($$!(&&+$$"&()+#!("$+%!+'+'(%'$*"!'$*""&"!%&)%'#+'"&(*'))$$"&*%&('((!%*&"%"$!$$(')!'#$"!*#*#(*##)"))(((!(##*&*)%(!!*&#**
@r8850
AACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTT
+
;451+7=9(&?@CB0=-+92GE&<0B9!++9;;6H/HA!.B8#.10E./H=*+B0#9&1F1C.0"'--+#7
@r8851
GATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCNGTTCCGGAAAACGCCGCTGCACCGACAGGGGGA
+
/>F7GF-*%!&30G)@*B5CC::85#%(3)&.".<&<+/48F/2+"E(=?576::.4#HA</="@B#;,G>
@r8852
AAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAANATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGNTCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAANATATATCAGCATCTAGCATGCA
+
+#+"('&*'!"*#%"('&+$*"!*++()+&"*")(+#"'"%#"()$)*!&#'()+!#)!$+&"&($+!!'$)!$')+(%&##()!*'&*#)(+"%*#%'&(%'#&("(#*$"$#!"('*&#"!&(!&'%"*%%(!&(")##%)#&(&%'*'!#!)*!%((*#$#*)##&#$)"**"(!!+'%
@r8853
GCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATC
+
4'F591%:601,A;:$"<3.EE3/:%*>4>#D3,-*F9$:@4/#6H6"?%$B(%9D%;$B)8$?#878H%&:9H785/)H!8+BC!#F.&#/#E"F4$B"D$&9H2DG2"9-/99-$
@r8854
CGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGG
+
:>!=--14>56FF.)5&4,57?%,,AF<51)$5B7H=%:3#>!C#BAF9%
@r8855
NTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAA
+
#8(@%351/8/*6%4'%-8)D'.'209><..=79G#$-,B?8!+5G:)@'H?!C3$!F#)!A*B$&9>4A3EFCA99'&&<=2)7):=<,(2#F:E..G<)C.=F,:%3((=G!$E#/BGG(79,.),9H%B0="E1*<0A9F$?$@=63+-?65-#DH;"''*=B.
@r8856
NGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCNCTCTTCCACCTGCTGATCTGCGACTTATNAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGA
+
*2?(+9/",+A67A)F).A(.0.85D6E#/@881:9+->B.A12#&7->&AB!$@65D3F##>G'>!=1@#'8$H"(EE#6,>&-&F3A"B#C987"9E><!C&1,2+*;"5763B(!,8=8".B:'<'6?C7((-#)
@r8857
ATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACG
+
+&)#$*)%(%'")"!%+($*"*)#(!'&#$%)&%*%%%*%'"("*&)($&&$
@r8858
ATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGTGCCATTGTGAAGGCGATGTATGCCGCCACCAGTGAGAGTGAGCTGGATACCCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCG
+
:?:A:+61+,/8?8<AD>,-GB#(!<>228(H1;BCA33(0.5.;/>/=/*G'(5$.E+3=29.#;)/%$>0@-2>(E#5GH+2;+G(&0&(<6+G@<D1*.B-!=,@-'H9C.$1?.#C+5!H+19G87'<%76+6B2+AG?"7($E+?.B91(;134==@E;@DF.BF4F-GA2F
@r8859
TCNNGCANAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTA
+
'%!"'""$+!****&!'"!"#)+!(#$%!+!(!$(("&"&"#!"+"'+!)((+#()#%#'")+)*+*
@r8860
CCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCG
+
G&!#E=@=0A+>1"E9+&&GC;(B/&D=*5C>?-1#1913<=E),@2((=50.2"4,*.D2-,!AB@F$
@r8861
TAATTGATTATTTGNCGTGGTTTGATGGCCTCCACACACGTTGTGATATGTAGA
+
-9G@H:0A:H;42=?E8%:8+#C8$!5,,9G<@B$%9-#"EH"G(:&H.'C?D0
@r8862
ACTGGCCGCAGCGCTCGGGAATGATCCACATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTG
+
*&5>@#DHC*/%>6'?%,D%20C$8@FG10'.<?,48(A/:0,$4B*47&/1,@FH4ED/'"=(3&)B>622@.,;-(."19H&1E;3
@r8863
TTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGG
+
F41A4BDD/#5*&D00G:FH,A5-%H02,9#52G&C0;DH=-26@@D27->""HG(&
@r8864
CGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATC
+
!(/=F5!#+(=2$,:-8846$A!96BD+79B"3(AG1H6/!D4.+**11#C1C-12CD?*0$1.C8).D-1=,B5?C<20E(&H@)B6447H=FBC#-4C-(,"F4&(FG;G72<?+$5,)7E9;.*F@41D"722!:%B@!G"?;6+.$1C,E4.--<@:@0B=9G9H+,E*/8
@r8865
NAACCCCCGGGTTNNGNCTATTTGTGAAAATTTTCNGGTTTAA
+
#)$$""(%%##*$!!!)(*())$!+""%!#"&#&!(#"$)&!"
@r8866
ATTGANATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAAGGC
+
"*'&)#+)")*&"$#%#""'%*)!!&"'*%#&**"(#(#%'($#%&#$++!+*)!#&""%*#!&!"$#*'#&&)&&")%+!""$
@r8867
ATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGG
+
;&7=--41A+BA(>H"8872$!384;.;00B6;H4-1H@6G@$,:0H58719FA:04C8"/<'?H=()@838%"=<=89,*+DBF'C2FH*36GD*<,3A,
@r8868
TGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCANATTAACGGCATGATATTG
+
7%D6,:C?1(!.61!<E$F)@,='&(GB4649E==D'2=66-:14GC1D+)'@!C+*.
@r8869
ACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCAC
+
=1C&&67<.*",%G#@=51%>:=AF5-*!&:5357":01)>?)F%:BD+%8(DD-A+.<*GAH+
@r8870
ATNCGNCCNTNNAGNCGGTGNNANNGGNTNCGGCTNACCAGNGTACNTGNCNTCGGNANTN
+
!#$$!"$!"$$"!#!"!"#"#"!#"#!!$!$!"$"##$!$!"$#$"#!$"$"""##!##"!
@r8871
TCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCT
+
6C+C4/7#!;"AB@(2D%>62,*0=11E<<0"%B=.'9;E1!/%'0@>.G%)
@r8872
TCCACNCAGGTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGNTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTC
+
&1E,GGE&=./C<?)EE4#6;E6H/(69,854@%F&8#<B4BF87)&*!B55"+04C3<A5(4B&94B>#$$"@)?7!?DH2"9<7>!GF&HF$4%+E(9(<G&?
@r8873
TGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCGACAGTCAGAATTTATTGAAGCAAATCT
+
+G+?7D0<234*G%FH!&B2;;(7&"%90/*?5:*DCA$E8?4*1H49<95,:C"#<CC)71E$A4$%D==-==9"AE8@"F7.0)HD89@'32F?>6.3AB-"0931G&&2F/C891B4*+?3$$A:B(<+38CH%4C3$C"*$1&'DD<&C6+'7@@!7<?,'"5.=+FB7$314.>2"385!B+&#/E/'"<6/>9)B7#*="06":B2D
@r8874
AAATCGTTGTAAATCCCCGTAAAGGCAGATNCGCGCCATGCCCGGTGACGCC
+
5-:*E%=43#=G612:#=$?'+#A1"-5D0<C)'2:21D86+'$EA6?,+';
@r8875
GTAAACCTTACGCCGGCCCACCGTTCCGCCGACCAGACTCTGCATATCT
+
G;FEB@4>?(%7G/!"!6!!<;@-><(3#"#7GH:;*.:<$7*<C0>9'
@r8876
CATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGA
+
1:B>2*"FAEC$A-,//&6HC88939,8?2+*G@"=%9.:5F354#/,;1CAB&8F
@r8877
ATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATNGTGTTCGATCCGAAAGGCTGGGC
+
&1#;*,=.8B!".H$;+4"6#".(>F-$/BFF0EE07=87.-"B7,B">/5=@',FA+@:)CD.BC=D*+=9G<G>(H#E"<6;8
@r8878
ACCAAAATCGAAGTTNCGAACAAGAAAGCGTCGAGCGAGCTTT
+
$%+$"+'$'!(+&+"!#)"!)%$"(#"&(%"$+($+)*)$$"+
@r8879
NAATGACGCTCNACTCNAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGAGGCCTGTTGCTGGCTGCCCTTNCGAA
+
'&(%"&"%)$&"%+"%%$!#+('&"'("!%"*")'+%$+)')$(&!&#$)"*$(**%*'$$#+##'("&#+"('$&(##)""*+#&(!)*(#((#%!$!'!
@r8880
CGGACTTCGTTGCTTTCCAGTTTATCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAG
+
+E:/@<=GH=H6D'#=>)D9,?;3E3*D5C,A-(A15#2;D-$%<7C+%-5+G)C-6=@9H54;B57@?*$45"D0008&-$;G+=*E?;C;;),24@1)H418&.>/C/*E5-0A
@r8881
TCAATANGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATATCCCGCCACATCCACCGAC
+
AB%D@0+H$C:A/+):@FF6+G)!*5/$((*&,6.+$C+)CE+9%*)G3@BCG8*0B(*+D6"FG5?(1<18/FH7%>H'B>9%<>;-+(#E!,=:
@r8882
NGGCAACCGAGCNTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAAGTTCGGCAGAGGTAACTTTGCCGGACAGGANCGTAATGTGGCAGATCTCGATAATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCTCNGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACNGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAA
+
+&*("%'&$+%%(+&"!**%$%'&"&+$+%&#$!&()+"*$%!)%&'"#()+#')&"*+!%%*!!"$(+#!!$+#$&%'%)#$!##!)*('"$*&&(%*&("($#%)"('#%#$)!)#')(%%!""$+!(($%+!%+"'(*!$#%$('"%+)''"*)%&*!$#(+$''$'!)%(#(&$"*'*+%))&(')&#*)##+#!''$++'*$''+"(#%$"#'!')&+)&'*!&'!*!!%&+'!##&+%#!$((+%*$$+!+%)&*#%**+%%&&"%'(!*+)*!($%$"*+!($%"#%''*#()"!+%+*$)!***)#%&#++$$&&(!*'!"(%%!&&%#('!!+%*#&"&(*)+$"+&&#&!&""&#)*)%"""
@r8883
CCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGN
+
ED(225(H.E45C@0<;*B@.*@A$>/G0=#?(0"$+/B;/!6F?-4
@r8884
TCCCTGTTCCTGCCAGTTCTNAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTNGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAANTAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTGAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCCTGCCCGTTAC
+
(8(G1H:!$D.6&AG&*.&B*.H?%G>E6#D9A#E<3)'0&#?04?<122*=)-!$67GGGG+;!#<(19GE61D"8&.4,G2A0/H:3EA#41402C-:<F-<C6%50#(E(:0!H=8+()(AE8(7#E@E>G!3F-0=BBBBC&2.5(/>)'E<.,$F/G$9(=&@G(%G<B/5G+71!/F+A?1$&9"66?-#,+03<+=!:8-!F3C8"7<C",.D:&$.G%#42.:1(:1H88G30+D;CF%F*?9''DFD=*(F';!@5;:6?)-9<+'9+3H
@r8885
TGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGANTGTGGCTGCCCTGTCTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTNCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATNCTNAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATNCGTCGATTTGGTGCCGTAATCGAAACTG
+
<G!&B2==!0%.498.,&5D@EF5!!B"<F6$@400:.H&5139&%+45.=5%?D.6E%G8G+!,4-69D5B:2)=A+@,2G:$G(<.#06:1G.9?7<<G4+(.+>:-.&@A3+E!.<&CE-'3=D600',5",+-+$-77?E)3-,0"!+@>A0,EC96)=$8%?62+:5@<@2@2<!+27A6C.!>!=E2.F?49?)-7391C"H%@3D(*4F/.##C7!.1-'DF1#0#F:>#H4<6E77=2285!(:!07#;316C78"9A97'.,$B:B=<94#H4(0")66>!('/6$E%80G7C"@6>E+<;3E$54A9%('B7#,FD(D4@=AA3D!.@2E3(':'7G1441?
@r8886
GGGGGCGCGTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAG
+
#&$'("*'&+#*&!*&&)#!)+'*&#!)'**+&*%'#&$%%%(&$%
@r8887
GGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGA
+
$+("#'#&&+"(&$&)%+*!#(#+%(&%%#)$*++$$%+)')*"!&%+*'("''
@r8888
TGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCC
+
>@:#06'#.,F2-%-$47<>7;A<2G/7)!4=92$#@1&BC
@r8889
CCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGTTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTG
+
9<B0=)G/"1>>'H!!?7#HC@*"@<?%"?$(5->47=-"5(C2G":'5)47'79&4G$0>H0"#>(E%.,D.H-%$/(H@!@<$94$%=::!5H7
@r8890
CTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCGCTGGTAATTCTTCT
+
*(/G:1"@5&85+9H%>C960@-/>7"F<1(-D,&#H45;-/@5#"@0*<)-*
@r8891
GCNTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAAC
+
=8&6<F82E>5)+;C>#'"/'--?12*@@!$)8..96E(@?
@r8892
ACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGANGTGCTTTAT
+
352GA&/2BFC-=./4G57F=.E)/346C*GEE'2&"E/"C7=D8+-5%)3!6>C//2)886
@r8893
ACACTAAACTCNANCATATAGTAACNCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCC
+
D7(2'#2.=!@38FF2%H&'(,A(=E<9-3C??*4B8/E1-G"+"D"79/'-5,,/(*&E4;=B#FCE)'83=,B)?/F75%DB!?9F<6<4=A%(?8B+%E@*$74=-/4
@r8894
TCNNCCNGTNGTTGNNNNGCGNCAGTNGCCCGAAGCGGTATGTGGTTTCCGTCGTCCGGGCN
+
*'&!('(#(%"()!!$$#$*&#)$&&#*#%+*))$#""(#*%#%$"(*!!&$%*('#("&!'
@r8895
GAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATA
+
HH#2)>B3%!G:<F:>F(49C&("(H>/)@%BDC5=?@:9*83*6$9A:((93'FG=19@*!==09=%4247@+%-=&=G301!<2G.(/>0.9<&%E9!A7F!E4D&/B')9;/G-9*4G5'
@r8896
ANGGAGAGCCATTCAACAAAGTTATCGAAGCGGAGAACATCAACGNCTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTNAAGAACTGAAAGAACACCAAGCCGCCTGATGGGCGTTTTTTC
+
"+)*("'"!('#""(*%(!)&**$"!&)"!"!!#**+'$$$"&#%#&(()'(*#(!'+&)%(%#"'$*"$*(+!!+'*&)')#$)+(%%&"$+&!"'$!+$&'#($&$#$*!$)$")"$#'&'"*"%*(#$)#+)"+*$!$$!!!#+$!"+"$
@r8897
GGCNGTCGGTCGGGCGAGCGATGATGCGGAAGATTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGA
+
&A?E*"E9)@E06&+B:9%=0!C(3$G-F"9979*8>(%%B4>%:/-F5'.D*/2#4)>&?$15;);2:/;0360,!=F28/7F
@r8898
GCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCG
+
?1"<;/&;1!E(?.,1!64B/*-#'$.!=.?A."F0(#E'CH#(-8+H&15+$(0.C@07.1+C&?
@r8899
GTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTGCGACGGCACCTGCAGAATACGCCCGCGCAGAGGATAATTACGGCTNAC
+
>6A.%&D&F=74+E%,;6:$6,*.@9?519=:3G2-=E#<FG1>&51)$&*5".9*.,+8H5-#723#32'1D8BH'65;#62$/$8,<>.C=<*A(C,7*&.
@r8900
ATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGNTGTAAATGTTAAATTCTAAAGAAACACGCATCNTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGTGTTACAANTATCCATGAACATAAAAGATATTACTATCCCTTTGATAATTCATTACTATTNACTGAGAGCATTCAGAACACT
+
+D0913*(H<'@#*/<G+A/'1#B5G;>-2@F.D.<D44)G:;!=F=:-%7;DA*-9/F<*)G2B+@8@::*(3=!3?2?B"C2D'4.7%!A&$501H),*()5/24@02%/>$&,C1+F67D360#/>GC7'<-?G$DC(;%?HG5%0>>?4F"=*.HC#"7H<<,HFD7'BC'H+<3."#H<,6;C)1E4DA;+12>&B!82)166F&.>4%-/D=&G%%/!*?&8%G)681EF1B8G)3F3/9FBED2;,.!GH)??2$F
@r8901
GGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCNCAGTGTTCTGCGGAAAAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAA
+
B1E(*"8<#5>C-2@F:4):9-C142(*8H,<5=8.29349=#0?&*<%@9A";"5:$A<;7<G452$'H&/>6<#E!>9.A<<<B-1.%6916/E#B"AD5DH;+=90(5'B9,01F<--0+-4<3B?78D%E1E3&(2$6A8-":7GG1BD19?0G)<E
@r8902
CGGGTGTGCTTCCTGATATGCNAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGT
+
9<F;/9D5-;)(=G(>2/%;6,3@(A<#1%F20&BE0",7C;;)89<54()3>G"D1(++$F'3B=H)A
@r8903
TCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTNTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTATTTTTCCGTGAGAGC
+
H7?-:95595$">3#(#G)==(6<2"HB:?<5(:+>>2&/<,G#CG04-&2?A$+<:!/('7,!11*G#2;58'6.C0>1&!-(:46%97=E&-"88#/5.#>*/F73((,&2=6F3<0*)%GBG4:;6&(%$A@)BHG"D3&=7A#"F1D&B16<9H%/B,
@r8904
ACTCTTTCGTAAAAGTTATNAGGAAATATAGTTCAACCGCA
+
415#,@+!2@A(@50G:?/6:=./CC!%39G/%3F?!F,%0
@r8905
GGTAACGCTGATGGGATTCACACCCACTCATTTTAGCCTGGCAAT
+
4#)1/BF*F!@"5H#;A:@6,6!@EC60+2%:3:1F0>9>FGCC#
@r8906
CGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTTGAATCCAATCGTATCCAGTTTGTTCATCAGGTNCGTGTAGCATCCGTGCAGAT
+
*#%-.GC,"G($D5,=/--+B)//DA0,B7@?>";0-;53>""F$@.$17%.G8""!;4)FEC23;$*(G%574-4!.2;F!7F-*'.@+&6#<-8@#FH
@r8907
CGCAGATCAGCNGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAA
+
@DE1</%DB9/A87E>*&"2B?B0D5E**B27&G@H>9@8F0,.@
@r8908
AAGGGGATGTATGGCGATTTGGCCATCGTNGTGTATTCCGGACAGTACGTGGAAAACGGCNTCAAAAAGAACTT
+
+)!$*(%&*!$+)'*'"!&"$&+!$&"%$#)(##$*$$%"$!(##(&%*""*("#!&'*+%"*$*'%$((!&#(
@r8909
CCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTA
+
B@.#F+F%$)B;@F:/+$9B:E.@=3+<>#@#9<*.!'#2-0/C;8%6):=,4CE&))4%::>G)7+B66=)3G2$<<.H>!90;4><>*
@r8910
CTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATNACATTTCAGGGAGTTGACTGGATTTTTTATCTATTAATGAATAAGTGCTTTCTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAG
+
>")7,488F;=+2$7:&2711,>5G982#H&'"<+!$)0-&//;4(!B9=H3&9)0BB2.@$4,E'H.!@@/#':#<,@:>:>=774-F>A3E4&>+0&G0A"*,:D9-H1&2H"-@<=(6$!91&#C1-,7,C#&B+79!8!&0>B#DC5)A;)2=5F72<C7;70/<H2?/
@r8911
CACGANACCGNCTCANTGNTGAAAACAGCCACAAAGCCAGCNGGAATATCTGGCGGTGCAAT
+
''#*(!"#%!("(**"$*%(+%#'(%'!%(*&(!(#"&"!')"#$"!%#*+!%#!()'!#)"
@r8912
NATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCANTCTTAAAAGCAAATGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACNTTTCTGCGGCATATCGCAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCANTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGAAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTNGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTNCCGGCGATAACCAGGTANAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGA
+
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
@r8913
AAAGCTCTGNATCAACGGNCTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTC
+
>+;"5+>2*3A;+$@>%"="4(6.D@-5$3,H3#"D,C'&F6-0BBDG#9%%B"%:9-
@r8914
CTGGCTGATAATCNTCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAA
+
+"8B=(C.,.:5;1C7#"@4A(.=:1D#,C:0$@4*5"<EB"+@-15B?1:000%6>AH;"=%?H*
@r8915
GCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATNNGTGGTGGTGCTC
+
&FE$)A?+)8F0*9@%,@97!>E05#H!)3-35A96B89*+A"=/.++6/!3&&%*/@46&?!G<43C,2$(9B
@r8916
CNCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACANCATTCACCGTNCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTG
+
A2#2!H?)!$#/;?B.8%=A%$$E0%EF:C'-H>$/+3.-"1:B"C+@+>0;71;'!FF=>G.C+4A4+#/(0#G+1!39&$3583,,*B'-F;%BE6<"7G?,<>7"8?H3+%:"4=51:)@@-.+452
@r8917
CCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACG
+
H%&(6E(7--'CE>&%G%@C4F()-?!@@#+F="?!G',!.8-F'H&)?A7EFA@*$>&**6#41F-*"/,>2*>?=//9
@r8918
CGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAGTTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTNCATATGGTT
+
5?!2GBF-==:-9)4;7>="*;::.(6H3C5(C4#@9-A.$%F4'CB+D"F,&:"+1;;0-<>/!G;*2BE,%0HC+#"7G%9(=>,BH7!%>:!+G"4!)>@<,*$<EH+H#%,:G
@r8919
CATAACGGTTTCGGGNTTTTTTATATCTGCACAACAGGTAAGANCATTGAGTCGATAATCGT
+
)3@3<49+?$@CH>*68E)0ED%!,+F'(+BG<-F>#0EF5BHH9&2=.)-$<(D/3)$A68
@r8920
GCTTCCGCTGNCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCANTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTAT
+
>G&C#%1$EG'E==C=.#G%E'9%0"#'H+G3?+1-2#D/?0;G.!"G2+7':5G7E37&&"!7(2=,A4%7''>%B16=6*0)$B&6DD0H.3(#G,37<+1;'
@r8921
ACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAG
+
F7$B;<C-F*%'70);#9+1GE8()2$!)3::C"$BCC19A+H0CE)CF9-28;1'":"!D@*B+(%9-&<E/%G)8
@r8922
ACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGA
+
C=1(>B?;3*/ED:A9FD,42*DC++3/1-,F+.'B;4:$$7D-
@r8923
TCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCG
+
AAG-H*,$0G1BCD:F'C>;-3?@(9689%69,2?#/7,;01.#'
@r8924
GTTAACACAAGAGCAGCTTGAGCACGCNCGTCGCCTTAAAGCAATTTATGAA
+
*="'GE<;"(-??&1&/5-7%$BDH89)3-2!!:73>7A14,4!C5!::;;F
@r8925
CCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACA
+
90,%<30*B=DE#:BH(<62$E*:69D?$$%:<35)%H0*+FF'%H@H3CAD-A88@42'@;B>146),1DF$@B4;,D,1(B>+@,A$>44>3#CF-5!H23/"8@*!;C@)H37(15!/4).'</6E",#/@G5A-@H7@,=.@**5EEC'@();C6:1%?=*:*G<7.(1G6;%E/!.?:
@r8926
CGCTCAGTTCGCTGCACTGCTCAATGCGCCANCGGCTGATCACCTCCT
+
762GH&5G&1AGE1"34=<F1/)+4'D0#?G&//+'CH3A%6().B.7
@r8927
AATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACACCGGCCCGTGCGGAAGGT
+
495A-C3C%F;%0#B43&$&?B!*>H(G"%)!?)"FC-.4:-F*#'%C:&()C3"!8)A-?1.'>H%F(
@r8928
ACANTGCNTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCA
+
$(*$+'$!##+&+)**'*'*((($'#""+*%+#***'+#%$%)%'(&*"%''&'$$"#*(')%#$#"$($#&)++!+''%*&+(*%(%"#$*%%&%)""#*&"*%!#('+#$##$+
@r8929
TTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATG
+
D+1A77$/9.7-9,C.%-B2G@B'HGG/3GF2;?<,CE7;?/*3=&2*F53?@>.C=((<?3349C1D:
@r8930
NCAGTCNGNNCTACCGTGCTNAAAGCGCCGCCCAGTGAGATGCGGC
+
!#*&(""$("#$+)"+!%"'"(+%%"*)***"%%'(''+')#&#%%
@r8931
ACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTNCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCG
+
G((F#%==C);AAG,9;3.&B7DF9%2/G#8F:G=4)434"'#((7C85<./9C?E)",HAE97+!!C-HH($08*:>.5&8:2C;7F/.+F2A5&@A+G.A#;F8,46+0;7D."81?"2CF(A=7@%:44??;@"5E&,+8::#&:4>B(FE;2#0/?<(;$18-3:@+&5:A"04707+:EC25*:3$D'%):",
@r8932
TTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCTCACCGTANACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCA
+
)F+;*FF/;H/+7FF@@.GD0A8:,H*D)A=E,:*$9.=<A83633<3,.(>?.G&4&-E*.,A&DA7'F%"EED88'3<(?<$:4<$!@&>;!0#@//3>H,/%17$/2(8F<089,->9$&9%'C3"?971";7
@r8933
GCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCC
+
BD+?5'9*#6F7B01);+%8.>G!2!775$3&,G>5>22*5$;->E31"C58,(:<"#9.03=1E(B>H6A1=*?;4A%-"10F"5FF9.88&:<?!#?C6@27?BA@G2*-1>8@127%-=26B65?,;>>B$!H.!?8$!0=<:'/98!1.7AG1-4<)/F-9*"G8HF3A;?G2)!96:?!5=$%2:4G?%C:BC23&'91?FB94"-9%F((5$&,$:-#;3$=0"DDD4D*>=!G*05&582%
@r8934
AGTGTATGCAGTATTNTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGAC
+
$"+*%%")$"!$%#*+)")"+!%'%%!%$$)*)'&!")!(%$'$#&&#(%'$**''&+'#!*$$)!+'&!'+!(
@r8935
NANCNATCGNNNACNGCANNCCCNNCGNTNNNNANTNCNCNNTCATTCNCGTNANGCCCGGTNNTANGNNAAA
+
!$!""#$#""!"$"#$$$"$$$$!!#!$$$$###!$!#"#!#"$!!"$!##$!!#!$$"$$!!"$$"$!"""!
@r8936
CGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCNGGACACNG
+
6G2=G79"/7-%6!13:;)<;6#=226#"0;):B3,:;6G42331<A2/#3$7%H9?D0*-)9:6-/<,&&A@8>2->;E(E700.
@r8937
CGTGGTGCAGAGNACGTTGAATGCCTGGAATTAATCACATTCCCC
+
6C1C21)F</.D=16%1C+C,=F6500&A568A#<),=!45+<;0
@r8938
TGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCG
+
C.-+7(=,;6+DE)6::214#?2829D>EC/171B),89*G@A8%C27>$+(%<"2&62<01D#(:-@E&&C
@r8939
CTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGAATGAATACACAGTGCAGTGTTTATTCTGTTAT
+
G(0,=C*A("35D3@@@-/F*C'%6+@E#AG$.70-?=9<86%0>;!D"DE=G89$CD4-#@,B>H46-BG78,#/23!>B,,30=$%A$*+1D)$;<3#9$!*@-G>&%1+6,H-+;+"5#D-B>/C2.</;H#=-7$6FC%?,#
@r8940
TNTGGCTTGGANGGGGCGTACCGCCTGCCGTTAACCGTCNCCGCTGAA
+
&#+!)!$#%$+*)$$%+%#"&+$#"&#*+%('#&*!)"!)'$)*("'(
@r8941
GGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTACCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGT
+
.9<*!>";-6/B2*G3-D?C6.87@0E&"4;7;F22B"<+)85@4.753()02BD>C<A#ED=3=<H8!EH$&BF;%')F&H23!
@r8942
TTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTCTTAATATTTATTAATNTATGTCAGGTGCGATGAATC
+
0#3?$7D4D4>:)H9;H+$5-F?%8,?;>9A59,:;59G29)G%2-B7)A*2<@99850,&3E!?>&-?B)CC:B
@r8943
GAAGCGGGGATAACTTCANTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTCCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAA
+
2-,@)(599!08G+:+BG4:C3!''1)>=AA,<!H1'H91H'=?F0!,".D!FGA*"'4"43$,EF,,H24*7>/;>25A3+G1CF=62H$0(3@C?G2#+C*>:-C:H?*:F+176?>!)5;E*H9*(4HG$C-$6<?+E4CC;1)F@F=;%0':2ED>-.<4$F0/C3$-)!)8(-9D%A(&>0,9!
@r8944
ATNCATCCNCNTATCGACAAAGACATTTTTTTTCGTGAGNAATGGGTATATGCAAATTTCGTTTCCGGAACNCCGGGTGCTATCAGTTTTTA
+
'%%))))(!("+#*+)*(*#(!!()*($)#!***#+")"""$!+%#%%)*)$"##%$%($')&"#)+)"!%!''++#')""!%"+*+%(#%+
@r8945
NGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAA
+
#<4(2#'8.:4$6?%)87B>%D%:7"441@+3479%%C#2FD4"1!?054:G+&1$7,<ED>
@r8946
CCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAA
+
%*+!'&"$**#*)%"#&!("&&(#"&(($)("%#%$#$&%"
@r8947
CACGATNATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTNCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATC
+
*)*("*#&(+($+(%*)&#!'!%'#)"$")!"*(&)!*!#$""+&&&"#*++"''&()!$(**#!'))#(())'%#'%*!"%'!"$#)&"%
@r8948
TACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCGCCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGNATTTAACTATANTGTGAGGCTTGCATAATGGAATT
+
G#4G?G:*B57E)D=A:=F;=DD;2"&7<981AG9$$%B0-=;:FB+6$D4@"*1>9<:4H*56A#28,)(A(@<D73F@<BCDBD!:D*$B/?,85D8)$52:+(=.17H;GH#680*-(!.D-%-.6-)44)/#&'.'.;.4C!7=$:87!AG=;*.C&B9?2D1*HF:D8:5,;@;2%G=<8+34H9!F+,*4C,9!
@r8949
CTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTC
+
9*FF8*-)<('+;0F0+!?+0;*&.&&4@B!9)=$:.DH17/'
@r8950
NGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAG
+
!</%7A;:,%,B(-++,/$3&(E5:+.05(34>,0)C<%<?$/G;$FBH2H#9D%-AG0"A$.&++3BC0$A/@7B(H8F+4F3=10<;*<?4/+>#"37F/23F344-0*4BA,0-+;DDB.1@$1**@=9+2=#)A5,E-314(;%
@r8951
ACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGG
+
(2.@"7B&2@?!'0D"1A5+CEB4(3:-CH0+=#+;94)1F("<46AF:7&@1',>@)4A*@;24!@6C8A,2?><2G%G1F+2&+;C(E:$;1
@r8952
CGAGCATAAGGCTGANAGCCTGATTGCAAAATTCAAAGAAGCGG
+
H6E9::(,@0,G8-;4=63+(%(G>A@25?9@8)$F(&*@942-
@r8953
GAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTT
+
6%6G0$/3H4%G+3)H:D5+$6:')$E3,9:6A6=74!-/>1C+3$6=DB8B*;$93CB/D0A3)1',?8D&:.
@r8954
GCTGGCATAACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGC
+
>C/6.55H@?>G@>C!4AG-<#EE9479F%0.A>?1++D1(+;!?:":+%C)6%D5BG0!6(3?=>E%$/F<
@r8955
CCCTCGTTAATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCNGGA
+
?):'*G@4&6$4'>*(?E;9=B7@.#+B53#GH+61E%'5H-$H-C(@0H7B489GE&E+4(6?@'"<88?0H
@r8956
TTCAAACTGGATACGATTGGATTCGACAACAGAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGNNCGTTGAATGCCTGGA
+
!!,28A"D("%+8D@52@/<9@2'%B"%'>,E;<?.63FB8:393(687/(?6)A!+=+8A=83D!;G9*'*):#@;E:$./D17+181!));5$7/$
@r8957
NGNGCTATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCGGTTATCCNAAATCCACTGAAAGCACAGCGGCTGGCTGAGNAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCATAGCCTTGCTCAAATTNGA
+
"11;A7HG!0CA56A9!<2=H*E.'59'%@9<=9-0+"HB9?2F33"+3B>-22H<6%7,+8+E791(8AAD3E8)#F'42*H;F$(3+A39'GA'D@)3D&A>*#2@A44&?,6/5,)-$)&;EED'==GA+A7%G>#EG/8#4+%56(<F")#&,*/F*D7#5&1A'(:>BF<;?#G3,#?A
@r8958
TATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGAT
+
"F*88.0@'GGC%4@6=?.HFE$&C7-7)94%G6*,/1CC>B+.C:7863.6%9)E624#7DH/
@r8959
AAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAGACGTCA
+
602$8G?"7$=%8,,>*:)(3G)=3>77B@2"=?>>B,-%
@r8960
AGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTG
+
3G8%>:9"=!?F&5CB9'=$)A6G<BHE?)-(C%B$$1D'1A0;0C*?+3:/8?6+B$7#2%!?">3-F43"
@r8961
GACGAAACGCCGGGAGCTGTNTGGCCAGTGCCCGGNTGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTANATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAA
+
=A=.E&GD:GB@:93&(,40-,8F!:4D:H=&"<E++>=4,6.06C51?6,!0.4H:?C/'*/2E94:$'@B0E.6F>/,:0BH>;(9/=6B@D@E$#+?$:+/='C/8)!660%F'E9D3/;33*;F;E$6:D96"7=0*H:$+)>2!D0!907-)260@3($?C$-+1?09'6/!D&GF0#HC2;';G74B/2%85C<1A:;/*9F14..;G>*5$GA@99F4G:;!,.%6C,(H@9%!%32G)A</%@CB<B-3*=@;
@r8962
TAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTGTCATTGCATGGGATCATTGGGTACTGTGGGTTT
+
/'?<+F#"*"!6H:":(#+!E?+,G3'5,&F8@"4"(@4FC>,81#1D%G>03G&&0%>"!G#7/E/!8D6)#<B!'?#:;6#-$=@BC87F-(CC@!F(>!&H:+7A.%(G'26;6<C@(&(6"B-&$/D*G,#)D&6-&!9C:"?F-F$9:.9:E%3
@r8963
GTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCNTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAAT
+
'=!=4&#B@#&-!*="5:CG07(@%F2G5..8<7$;#6'>F#C#=4G8;!B+B<<.%H#5?;H?;54%9B$5)3*389GG"93/;HB+?
@r8964
NTCTNCGTGCTAGTTCTGNCTGATTTCCGTATGCTTCAACGAGCATGTNTGG
+
&'(*&''+!$&$(''*$&(*$(!!"%*+$*"+$+'&'$'#++)(%(*%*+#'
@r8965
CAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATANATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTNCCGATTAAAAAATCTGTCAGATCGGAT
+
B2/H7+>0H*</"G!/4A8*HA.$/<<AG2#0/0G>($'!-9(D"C1+AC2*8B10>F,D8##<!H!<.H-F&@D5-6&)5%:-?*01801F4EB@1C?,%4!?B07$6GFD3?:'/@E8;AF.E+8E6$48F@-2/#"+.7(=4=B5*78:('D3&8#<DD@%4,323-1;?/$B*<DC@,A1+!C/"#>4"@F%8.DCE76FA%/=*,#F0.87)>.EA#"
@r8966
GCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGG
+
2'!8#;*H@#2:D+8!.-;(H=4C.?%>$H0G283D,>A:H
@r8967
GNAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCA
+
$!3868.5C/&9>?)3D47>&-E+1'?=,@E5B5+&5%=?/&/%C)4/$-<;*?:-???6;'"A3#A"1<2!HD:7DC):(0/-
@r8968
TCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGNAG
+
?#-?*(GD#@-2:2HC/-*'%E)4)B"<BH*0/!H1D!9+(5842@-3):2HEA
@r8969
ACGGGCNCACTGAATCATGGCTTTATGACGTAACATCCGTTTGG
+
"5.:.%FB!4"DB&G4==+?#'3.$+(.9E'839?204<8*.0)
@r8970
GCATTGCACCACCAGAGCGTCNTACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATC
+
,'F5,((84A:()<?<7E16,#0>(H<+FG+0(;815(@1*H4'=1>A%15@(+!#)B#CE&<*")422)#B=9&>530
@r8971
GANGATGNTNACNNNCCNNAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTNCATCAGCTGCTCAGGTCGCGGCCGTTGTGACT
+
%%'!$"*'&!&*&!")&'!+'(("$!*)#&)'%$'!"(#$##'(&)+!"%+)$('")'#+)+&%(++%&%*&')((&#!$'&$%+$!$#(("$'"'))!+%!+#&#+&&(&)#!*%!++"&+*""'&*#'#))*)"**'&!*'$)#("$+$""%$#
@r8972
GTCCGGTGTCAGGGAAAAGGCCGGAGNATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCA
+
=(68F>.4&*(%5(*AA<%0<G@1(%4'/:65)>F%9D&5E1.8.4E?3>5&(H8>H/%>EH>$9A$4
@r8973
TNANANCNGAGAAATNATNCNNCTNACAAATTCCGGGACTG
+
&)*&!%$"))))$'"#"$!%"!#&#'%*&)+%+%!(#)+)(
@r8974
CTATCTAANNTACCCNTNGTCAGGTGANCCACTACTAAGGT
+
!)"$"&&*&%%)'*&))"!$%#)*(#&!%!&+%!%")&'+!
@r8975
CGTCCCCCGGCAGANCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCANGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCA
+
3+2=D:?<0/9A;3>?8+2$B)B;$<=@E6$71'!/7HE8#BF0H938277"E7G1%7C:9A#@&&3+C?*)BH2DFC.?=C9B<'+530$,=7)E8;")?%>517""*/B"4..
@r8976
GCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTNATCTGCGGATTCACTTCNTGCTTCGGCTTGACATATCCCGG
+
.F@5AE0C00A><?H#&C!&:/5-5'E:)G>EA!@=,08@B#$:%8?/(F$&-;99*.?!36F?08-H42=*A(<>/AHB)4(:=91C=%)'+094(D'H+(64"4DA&%F#->%HB%=38G@)')>+F4&A>E32!HH
@r8977
ACCTGCCNGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTNGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGACCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATCGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTNTAATTCAGCGTG
+
!&#'%)'#+*"*%)+')*""*%!%*#(!&$&#*&##)!$**+'(*#'**%$##+$#%$'!#!+!%*&"$%&#!'#(($'!(%&%**$'&))+(!)&""$'&"$#$$$'#&#$&"!)'(!"$%'#&!*$&#**"')++$'*&!*!&++&'*''&(((!$%'&$)*&)$$(*%&"'""!'#$&*!%$$#$++'(!%)#!(!!'+&''**!%'*%)+((*()$&$)('#''"&""*%%(%$+$($$*&)*!+*%&&$
@r8978
TATGGAGTAATCTTTTAATTTTAAATAAGTTNTTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCT
+
/"/+@1C-FDD)0<>*9E)*<?/8,/CD$$H9$=83H#F$3340@4%5"EEA3:=3C?&F)G#?2616@5!385H#G7D:5'C*</1.GAH8#295)F8@F69&H-!'<#@7(03?-%/:4@C1
@r8979
GCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTT
+
474*3H!@=;/5"866?-7#D':)@5D<D#-E<A:%1/&=6*%A)6E-*+B";!,$85')5>%$4-:#774$=B05->*-&:H)(#;G2!
@r8980
CTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAA
+
3,46$4B$;7*#H,:D':+0+;.B?D7,HC+!:45#+&&&;
@r8981
ACNACGTTTAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACA
+
>F0D;C$?=#.&4!+2.89E68;$@%/FDA9G9)+D9'H**DDH4.),B73-98,G
@r8982
CGGTAACGCAGATCGGATGATTACGGTCNTTGCGGTAAATCCGGCATGTACAGGATTCATTGNNCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTNCATTGATGATGCGGGACCAGCCATCAACGCNCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTNCTTTCGTCCACGGATTAAGGCCNTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTCTTAAATGCC
+
6>C)D8#$1<2+/!$@?%1!E!7(*-(5AD"%F-D?)D6.3>24@F;3?6?7(6H79&:5F:5+?F8EF51/44*3!5G%,H9);&7/-CDD93-*#9<+$/FG>-=.2<"?.B:810$7@$>82C#07D(?6E0#8F6=?&B3%+B+)B;A'&A$))%3A3.B>2"(:A87.7/78?6?G7?>CE#858*D-F!,-:!$(3+,%)9/8(:6,E<0=)0&7'(,;&>A.BDB7=!0>%5*A1"&C'<=E<DC*1BG6.F25)%G
@r8983
TTTATGTCGAGCAAAGCAAAACNGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCNCGAAAAGCATCAGGTNTTTCCTTCGAAGGGGATCCGCCTAC
+
H%4;1:(=63,!+-$351/1>76G91947,5:-0HG5%*>/-@15:$!6-(5G!*F)5,'0(,C?C!/606H.23.E7>280@>!@)A$1AHA@%%,-)+20"AA#>B/C(E-$&2G=;CDE6FAH!-31H#',5FE@/@CF<3';+=<(8=14.)G8C$-?/@EHG<">33'GB-(%D3B93*8"4)&/'#@HAB3:"B,B(CH>"D3=FDA0>1@!:=:-FD<8,*)H,4
@r8984
TGNNTTNGNNNGNNGCGNATATTGNNTNNNNNANNNNANCCCNGANNGCANNANNNCNATACNNCCNNNNNNCAGCGCCGTCNNCNNG
+
"!!$""##"!!""$"$$!$!!$#$!#"""#!!"!$#!!#"#!$$$"!$!##$"#""#$"$"!!!!#$#!!""##""$#!$!"!!""#$
@r8985
AGCCGGAATATCTGGCGGTGCAANATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTATT
+
<:,7>0"DEA"8E7*;<&.)1&4,6D!A)@6/1C=E1.21F?8D%>%>>F?"(<(99(F<4,D71=FF09>6G?(BAC$)'!-!%6@02C,2B/)F7)"<$'<6/F?%4"@'6*G!<+"8'D7-&3=&HE=$9;8@%
@r8986
TTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTC
+
,#25,>,<%=61;$G;51F3:$)F4(#$*2:-B)%$89B4D4%?F;F,$"?E%",#10&319=9<0<4-0??"+%$0/<,4F-(CF
@r8987
GTTTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAA
+
,%"H<0"%'>*,3*330<)#""54%EHB2-&0)7282D!F9H0>".'%6@?=,%@F8>E+.$1#6A@05!G9$"8<F,@729-9-..?(:&
@r8988
GGGCNCCNCTGNNCTGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACNCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTGNGGTGCTGCACCGCTGGCGGCGTCACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGT
+
)'&'$&%%%*)&!*++#$"%'"$(+!$+%)"$"!+#)*")*$+&'"'$)))""$('+%'!&'&%"++#(#+'%*&#$()("'"!+)$!()"&*++*$*$$'"!&$$')&'%!#)#'&%(')(!#("(&!#!!&&*'!#!!*)"))*$"(*")!!!"()+)+%&'#$#&#))*+$&#""&'$*)&')(+%%*$)(')&"%&'"(%
@r8989
TGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGCATATTATCGTGAG
+
'.2";;:2$B>0:G=(890C!)/H<D>!>0"6?@'+4,;"'745+9C99*
@r8990
NTTGTATGGAACAACGCATAATCCTGAAAGATTATGCCATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACGNCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGGTGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAA
+
&G:<GFG!00&>'@D261/-=4"<.4'//5G@642-!?2)#F18;*(C'&3-5#-"1,871B,@B10.B.;*FC:*=#,1873HG7>EB8A1$=,D:(BH?!-3)0G(8%#":%!6%ED$=?&1?0-10>%'3(E+=2:B64CFG&4C1,6(?>('@C-:0%DA0*,6H56B:"(H."3EF&#07("B+E
@r8991
TGNTCNGGANCNCNATNCNATNAANNNNANCAGATAGNCNTNANTNANNACNACN
+
#!!$!"###!!#"!$$""!$$#$#!$!!!!#"##!"##$"$##"""#!#$$"$$!
@r8992
GTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCGTCCA
+
9D.-E3.-14"+%2"8.?"79@6H$!?2095;F#?*CE'":>1,@E?*<A<<$-@7CF*H<"18ED-.<790?=D'*!3D$=(,-(B2&F1H!1*
@r8993
NATGNTCNNTGTTAANTCTCGCTGTCAGAGGCTTGTGTNTGTGTCCTGAGAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGNTTCGCCTGTCTCTGCCTAATCCAAACTCNTTAC
+
)'&%&%#%'(&($&#$*)+"#*#"*$%)+#'(&)$'+")#$""+(&!($&(#+%"(%"(**!*!*&)%*($#$)%#**(+)$)+*"')&#'&$"()&$+#*(&*")&+%(")&'#)&'!$%$*
@r8994
CAGGCNNGTTGGTAATCGCAGGCCTTNTTATTTGGGGGNGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCNAAC
+
(!)*&&&#$+)!$#!(!"%(#+"$$'$'#$((*($"*%&&!&++)!(+*(+()(#()*'#)+&)#()!%))$)&)')""''""(!'#(%"%+($&#&((!$+)"%))*'!%+*%#%&#*+!&)$($&*+#)!%#!"#%!(
@r8995
TTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATN
+
?EAC%?7>G7*'.,1.2A?%E,5#16"(D"&294,,&90..4-F)5-&,G3;DFF,2+0+=5"183H!FE
@r8996
AANGAGNGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAA
+
&%""&#$+$*!#"#!+'+*#!%)##+!)((!!*(#&&$#+%'%(&()&)"#+(
@r8997
ATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGA
+
%;B1F8$66?<&@B5#-54C&5:-;"14AD!9H@)@A?<+>D<5H./G<59-C19?31C&!&?<G;*:>,&+15*C(+>6):>C.(E*+;9=!EE,(
@r8998
NNTTCNGNACNGGNANGNGCNCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACG
+
#$*$*!#'((%(*)&!#!%'"%%+*&$#)!#$'*#%())*+)"**+!!$*(((*$&$!'"*+'#"
@r8999
CACTCCAGAGAGGCACAAAGCCTCGCAATCCAGTGCAAAG
+
D21+,7G/2@;?=55019*F:5$H?0B(/4D$@-E/%@B)
@r9000
GATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCC
+
0$,B29$D:$>3A5@(=)2/:C/A'(4.F!C)4#*8B4)9!*AHAG6!1?)@<=#)+%.+
@r9001
ATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATAATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCNGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTNTCCAGCTCG
+
,<(5/'$-D0H+!FCBCCD:!&"$-"58D:1.<'#+5!7D'?2A,17(:*D2/4)@%/4C2,HB!;.*74:%8@$=:.$0ADF9"C$==?7?/9#.5!F!@8?(),>&8!(;6H5:7(C,#-)5"(+>54;)-E1>>!!&3,-'.4>E0(=.34&HFF!GD<#EB8>'9+44GA'5>A(8-E"$?"&F9=;$=B("<34#G/9F-+/&(63G&.#@;*(!E""6>8.H56<;%5C:!0'%&;,1?%</>.C'=A,H'"794<,+6/=)2G/<64832!4664HE+0%3!3/(*2H<>@C>#8)0/+B?39CH*:8D62,FD+C>#-AB4C04.
@r9002
CTGCAAGACTCTATGAGAAGCNGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGT
+
52,A!7978;749%@8".G'B'%B@"(9/(H*;'H#$)092/4&93&0,+%<"09>&=>9;,@,#*5G>25(;H)&%G9A<FGG<3;EC="2#*#-*C;@H:8756>0*%$=DDA$%/E"EC"/'&<5"(*H:+B<)(G<3=79@@/81A7@3&"@,G,'(C0+1:!:"G-C1'(<!#7'!9=1!/+4&F!E3*?D.H!-5>'/.6@"04#()"2$H,-?3H1+>(<G4';=.
@r9003
GGNTANTTGGGANGGTGTTCTGGTCGGCGCATAGCTGATAAGAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACACCCCTCAGANCATAACATAG
+
&$!#"""#'*"+"'")'!'&%%!&**%')(##&("*!$!)(!(#')#%"')))(!!&*&#%*$))*&(%%%(&%%*"")""&+**&)$)%")')*($&#&!()
@r9004
ACAGACTAAATAGTTTGAATGATTGGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGA
+
1CC!7G.$A#*$?9=$$"F=-?5(-C!$F?;##=E?(5E%5!&6%CH?!C&3%B@?966;6-:".>GB3B1H8"//B0:4$?&)@!+)8-%B&?)!-2*D63>F;-58B
@r9005
TCCGTATCGCGTCGAACTGANTAGCCGCATCGGGCAGGAAGNAGTAGACGAAATCGANTCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGT
+
@E>(&4:8%,,6!"84*'<?GC.G(A6#E=>-&<57.FF/;04D!(B6H3!,:19F2E85:"'5C&,5!6?)F'G9)(2*"H,9&-619@A?>GE1%#%C@=,1B4E-3%;F>6=6="A2G6*835+&5'"@H6?$@'EH+",17,"%:4C::@
@r9006
GGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGA
+
F5>B6<1;&.36?>=$*A3$?3'D,:(F"(3'H7!#":,"%0EF?B)="<"8%$
@r9007
AGCCAGTGAGCATATTGCGCCGCTTCNGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCGGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACANCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTNTGCGGTTAGTTAGTATANTGTAAAGCTGAGTATTGGTTTATTTGGCGATT
+
::+,+@=((/CG;.1:72=$?%6H810'7(A2&7)")#D'<+,(#B%#8,'?3::A;@2B6E*A@!#G"1C*?->4F5>)9ED#92);?#,2B<F+.51BD7?."*!HBC(;>!1+<:3>#BAHB1E&-#6:$$<98#4D20F2=>E!!8.((F746E3+H/&'#@8G-,,??68,86.G'3587)4<2H?.#"$@@2DG;!7F*D,B";2G$*>0%GF67'<96@A$''&;%+**5646,#='/5-+++4!<.0('*)D!GH
@r9008
GCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCA
+
9$/;-?'+#F(">#)(DG?H.A1>G-*753;453%%C+#5'6(;@>$-19%0&726*C6%!A9/6.C3'5'/=?4:));)H2#%>D:/*)"'/3E>;?970-)48@@$3+D4940;
@r9009
ATTANCNNTNTGNNAACNNNCCAATNATNNNGGANTCANNTNNNNANGTTAGNGTCGNNNCNACNNTNGNNACGNNTANGNNNANNTAGTNNTANCAANCTNCNGNNANCGNAN
+
#"#!$$!#"!$$$"!$$#!!!""""!"#$$"""$!$$!"!$$""#$##$#$##"!#""$$$""$"!"$##!#!"$#$"!$"!$$$"$$"!$#$$!!!""""$!#"$"#$$#"#!
@r9010
CNAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCGC
+
(%&(+'&#%+++)!++))*)!%)+)!""+$**"!%+'"+!"++!($$)'&%+!%+*'"#)'%'""%(*"+(*)!$#)!%!&*'+!"$!*''%%'$&+')""*$(+#*+##%+$%')!)&(!*"
@r9011
AAAAGCTGCGCCGGGAGGTTGAAGNACTGCGGCAGGNCAGCGAGGCA
+
:(AG*3,:8*:9FE@!"@-&24HA;BEF52'0-"%0>C2H!#7C!0B
@r9012
CCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCNCACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACCCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCANGGCAGACCACCGGGGTGGC
+
89H%:H2)$A%@5;$?#/7E%F#;",@6/./$!E9#CFG;34?.#$A?E'H2;>4.CFG48%H.&0(((,&5;AAHH7B?,G5H6*!6A70)-'%$<)AD8B%.,-%*8?D)&(C$A4@CD@/EB>#+D&H(#G#82G*A+%8%?'>BF($/H1H>H0#99*2##)#-/AE'H&4,@7*.1"&;,)?-1;?5
@r9013
NAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTG
+
!@04>>?9/,/9--%FG4D-<H$*:<>F20.@9<4;7%(,#<81-G740@&?H>2:"A9#+A<*$&FA*%;@2-310!"@%C+408.73///$<9#=/:0G369><:51E(04B2C>=#EB$;#%.AD2<#<0779!F(B$GA94FHB+$H7
@r9014
GCGAGGTGGCGCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACNTGCCCCCCCTGTNGNAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACT
+
5B-,650()C;GH)1DB>-81:45'B5/@;B'G,E07!0%&,5<1,H;F?</E)-9,2$E27<H4=%?&=7?F+#*&-37:>$15*6@&/33-3",@(7?E=+>?8,+:7G05(::GEB'D)<)@%F=!($6G054$&;$%9H'4#97$22<6@./"#B6H+42A"$+)G08H!?;@?8":!?59D>G/<("*<92:#1B=@2D><:>)?./+.(,"4;:1)8%%%@@:1:;)#(9HC</(##<&&''-!;,;3(:?
@r9015
CCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTTCCCATCCNTTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGNAAGCGCCTGCAATGACCCCGCTGATGCTTGACACC
+
&$#(+"!$!#%!(+%!&!)""!)#"+&*(#%!(*!(&+$(&'%)*!("&*(#&!+'#""*%$##%%%!+(!&+("'#)("$##+'#*+'#%+(*+(*+*&(%#("')*$'$+#%%)++++!!!#$(*#$''#+*"+(*'%&!*&!$$#(%(%#!($'"('##&('*%%)$*#%!%+$*&"'#$*$(*"'($&$!*'&#*""'
@r9016
GCATTGAAGCAGCAGGATGTTGTTCCTGACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGTGCTATTAGAGCTTATACAGGCATTCGGTNCAGAGCGTAGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAG
+
5!DD$DB(='3<5*2("+8%<(+;0C!968::5&:E#G/E>#B@D+-BB2(B>.1#'?$-%40H!&;A.+B;?7&(F=0G(E8<<-*5B!=B#-;&"B(BF2!536B)E069(A/GH,3%EC?E.F;G?%07*,&-)3"1.*)DE+A7+EG&.230;474@<D*?H!A5*26B&C-=0>:':1809C6BE8AG,)26%45#?B"?.75FFG>C*-?G0?B
@r9017
AACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTC
+
=$9'E%-.8-E+@1-F=<(%&8!DG>$35A8:3.*F::E)/5F?>?*%>$ED%264%47)12)>&<=F1!?)DHGH8=8./0@3&A?506/BH=B--,,
@r9018
CGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCGGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGC
+
7C/#<7;"7&@'%C:'@C@CB@'05"AE)@+5.C(,8H<$5&:A=%#;8<+4.=3G21H)0<%G1.&/5*A;4G(1/(?,E<1>7?7...379CF;:F?0;/56
@r9019
GAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGC
+
4"09FA4F8%$#G#''&1)B+?D$38<((4%'A!9!.7:9C!C,@=$*/F*<1'8@1&$>3.*D;D76F:3*"?"G!*1A!''F?.AD00/+=1A-CD!D':GA++)>."",39GA+$E$#..*=#@:&D113664F@,<3#6-5H')B!51HG,BA)E0.63-4*#,+>A*$#A9%A'+5!,./<C7&$.0A$.1HB=A-F)=6GF1G#4A%=(:8C4FCH>'#4BC8?6+28F(
@r9020
GAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGNGTGAGATNGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGCTCTGCTCGA
+
B7&!6+D:G<*"<2'%8A$7>-)GD&;E*?*9F"*.4<43:=<)-6E9)9!-,B-*!"(H#2D#)G>FD47@72E))2G/?2#%-HA6>@0+@C>H2;0?*>7%(9>>;49*,@4G9/&+D+HH46+!9F/0@""=@1;";--27@.354"<,H+FDF2/;>B9B5$:,,9!
@r9021
TTACCGCAGCATTGAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGG
+
->EA4'A7:.!&C&#93'->-C+!>"5)#:D&<D!::H@")E;?C7@4+GD=81!0FCG>>9/:-!(C(A6!5;6B+C4GB11H+54/-=ECA-0,%"7'7!%;>C81+A=3F1&4?=$+-,>=1:77%/4*?
@r9022
CCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCNGAGATGGGATTCGGA
+
.EF$3)F(C<D44#=$DE;%.?BD9,@*H.G&0?3@<*,=:<@!9*G8)
@r9023
TATGCGAAATGAAGTGGTCTGATNTCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATNTTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAANGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATNCGGCAC
+
6,C<965:)EB$.!%6FD3$G3;7/&:B>;,GF/$HD*%,7;/D,+F2@*!6"<;2+4*DF0+;57=,9.D(A@'*156E7708%$#:#*2.1<-GB=F@8C?/E(%:'F,A"87+":3>'09'=B*-$,';?=?(.:9='<?7!/)!01<,'+);1;D<?6;84+F7G>G$?'7$?4':812G.")F%354BB3-&=<G:E;)5
@r9024
TGNTTNACATANTNTCATTTGTAATAAANTCAATGTCATTTTCTTCAATGTAAAATGAANTAAGAGTAGCCTTTGCCTCGCTATACATTTCTANATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGC
+
%%"$$$*(*($!&)++&%+%!(%+!%%#!!*()#*#"*&'%$+"++*)*"$&!!""%('"#$'$+!*&+%!*+!$(&"%*($!'&%+(*&%)"+#%#(#'!$(#(%!**$"(&'(%)"+')&*$!"(%"$##%
@r9025
GGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTNT
+
2)6(9!=F84$1==$;5D->'1??1DB907#0*5G,@*&89#-69@BA5<26?$'4D("5GAE4/)6'F,EE91><E$&(61$4+8/)&A%$:7C2;:>A)&)>C*0+.
@r9026
TAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTA
+
3,6A9#(-=G:(62,9)$($;C=1CG;E?):=@8$-/0ABA"
@r9027
TATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGC
+
3'!*()!7-;)$>@?B%-3<35'1-5/EG.3!*(FE??F!BE
@r9028
AAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAANCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTNGCTTATGCGGATTATT
+
'+*747<F'116:5HF7?)#EA*".3E934607?-4.4*$B/32$G%*.)@$;'4"$:*'!&7E7<(79BE<&!.7)8EG42/#-(5@)H;+16%@#685(&?/0"84C+.,1->!5&",A'+65"H">>F
@r9029
CACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGNTCTGATTATTGGAAATCTTCTTTNCCCTCCAGTGTGNGGGCGATTTTTTATCTGTGAGGATATTAACAGATNTCAAACATCAAAAAATACATCATTGATTACGACTNGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGCGGAAAAANTTCACCAGATTAATAATTTCTGGTCNGACTCT
+
&+(!$+""'!#*#!#&")%'$))%"#&&#+*"'"'(%%!$""(%#"&!***#&$#+!)&(*!(')+#''%+#&'!"(*(&#"&!&!&*'#*$&("('")(%#)'%##*&+%$'+(+%%%!"$')$&%$'#$)'($*'$&'*)+)+(()&'(+"+**&')#)%"'#)"*#''&#+&#%!'(*$%+#)&$'"**'#'%$%(##%!*##*%+%(#!+(%*'((*"+**)(%(%"+"!)*(!"%(*%##"*#*%&#+&*&(*&&"))()!%
@r9030
CAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTG
+
D6/C?0BB*0@H4@5?6F6F,!E"8'#BC0:---=.3#>%>#D#:0@,=HF'B/?%?>A"3!2!593H
@r9031
CTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGACGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCC
+
20,=,=<C%DFB&!9!6-:'<3GC:@A$()&76&GH?9$D7/3@F/-7-<><4'(AE+GE28!9?3E0-@@G&DAB,*-4<<%0%*0.E>84?%9,#B9@?G35/57#B>B5A/:DC7:30?=!<!4>*#7B4D>7F8-'B"';>!BD"<
@r9032
ATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCNCCCAGCCNTTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTC
+
:/:2'<1HG;+02*C$:+>FB:=(35/'D.%F&A*@+6B6#>@'3!D.0'@<-G%.4@;,26%>-F''173%$E8+C"*1'60?)"9B<"H-H
@r9033
CCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAA
+
F?CED*=&<!620++$836G*E3<?)!;5<*)E=692,5'B,6/C<&GE>301B416G7E=12%+)<,E"&!.9A+*F71>,A="'H**BG2HD2!HB8-A84F$-<G>1,34A5E:@D:'D-''10@2$(B#E,C1#0E9=.!#!..0$"G7EC=;@G*::4EC4+C<D"A6<>
@r9034
CTCTCCCGTGANGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGNGGGCTGGAA
+
!$%"+&*!)*#")!#%&#**(!)'%%%$("%%$+$$&&%('$!*%"&!"+&*&)*!+!$
@r9035
TCTTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGC
+
%*"-%;;"H5D?<D>70ACF*;'*B:6:4@F/@6*"C3409H+#/*@=F2(9,1H0+G
@r9036
CCCCCAATCNNTTTGCTCAGACTCTAACTCATTGANACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGNAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGNCGACGCGAAATTCAGCAT
+
)!#&'&%(*#"+$"(")"(#)!!'!$""##'*&!!!&)+&($$'($"(%&%*'+$#&')!)!#+&!"(%%&%*$$)"%)+)%&+)++"$&$$"**#!#(%(&)(&(%&'!%"*')#$#*!'&'$!'$##'(("'#)"&$')$%+'*%)'*'"($!%(')&$%*()#++#((%$"+#"(+)*%%"#!)&%*#*(("**$)!!
@r9037
AATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGC
+
G.<65.,%&.28?3(/EAC)'@<7G32G8E!9C49H7,H3'=
@r9038
GGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATG
+
+"#**'%$#*(&')*$"+!'!!(!%"""%)#+"%)"*("&&)#(!$'*+!+!%'%$(*+('"%++)$'%+(*#$&'%&'*"&"$*#%!+"$)'$)%"#&)'
@r9039
TAGAATATGATGAAAGATAGAAAATTACGACACTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGNCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACA
+
B$<E,H&.%9BG?9:!!6;<,.0=/D7%!C+#'F(5G"*=+,+*#>3DH,('$=B:A;3"8>4%#H1/>7B="H:!4*$)<GH>4$F,$B:)+&"9!/&**.D!5D@8!38$1#(GA:=/5?FG:CC1BBFE
@r9040
CTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCT
+
=AG5,7D&D/B*E+75.3/3*$ECH:0$(9#-:04%"H#<5$FHC)>+0
@r9041
TTCCCTGCCTCCNAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCNTCCAGTTCGCCGGGCATTCAA
+
*+;#2##,4.30@+<($H+A2G4CC+B7+//#(%9,/.7'F=9$0&(;B6C)''D2();((A->.4E:(8?3!E*3B(.=0E/-/C121;(C+40/=4=+
@r9042
CGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGCTAATCACCACATGGTTATTCTGCT
+
2B5(!D=6->D&G09$8.4+HD!C.7&EH20#5*4/D-3:?)#D&FCH&E54,<"?,B#<&H$)'&8D4:&-6>0*EH-FD9@-"1>%
@r9043
GCTGCTCGTTGAGTTTTGATTTNGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTGCTCCTNGTCGCGGCGTTTGATGTATNGC
+
**)#D?9";:'+!);<?E>#C+HF>B6,1#9C),%C0!G),#9*>5/>;+*:'1&%&;CC?'(32!:4FC!/@D*B-,?,-9D>C/F4<2F@6*,%<8(G/-D&
@r9044
CCTGTGTGCTGGTTCCTTTAACNGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGNTTTCNTCCCGTAANCAAACGACGATGNGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTACGGCTTAA
+
&,C>1%'7%AD%-1*-/(.'$;H1&&?8A(9:2%G:.!+#C/0046->)+,?"1-?*'A.)$1@9$!"BA4G%<)0,A>H.D')*.2F;0B,370-/&()(D?D$2%7+;4*9<FD"(E-@'**B3=5)',D(H2>B@;<'=E9F,B8!37A137!8A+A*)34<G;81:EC=-*)>;/2;A55B!AD*,7<@D+.==!1%91?.0"D%.4.*9@0>D.#>E9@H?5BE;(7G90F)D5)D/14H3&!$3,=:"B45<<#A-(-'!.105/')C:.3@886=
@r9045
TGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCT
+
)<'$0E&>"3@AG>F.9D+/92(3)5&$@CD#5GC56.,::?.DG"?0H&.=7*%<.6$AE!5BA(B3"
@r9046
CATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGGATTCTGGCTTGAGG
+
27EG1>H*F-(.C&/(A6<73+&8/:$H#':C0G6BC,BD(C$.7.?4%#(&D%;09H;.#?(&G-145F?<1'?!)G)8&:,/FFA:2?$3578#=A6!E4,)9#30"'A*
@r9047
GGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAG
+
HF93%0@AAE<+&G*)$?=@%-'!%&=$<;2%=850'<96B3?,5+=)-206C!#&<BE9H(645'E6B7F+148GF=#:(0#)3*9
@r9048
TGCTCTTCNAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGT
+
EBA366+E*24'$5;G#<*G=#(>?D)4/%2%B#&2:;!C5'&C%/#&&G1CH%8",.H-45H?,(F+?4DC"HD!
@r9049
NACATCATGAAAATAATGGGTACTGTAAAAGGGGTGCCAGTCGGCATACTCCGTGGATGACATCC
+
(9F5@7)H0>+*;90'$%G$=GCFA'#D.&EAF0;:;D&).23-&*1:G-72#%;%4$50A8!$#
@r9050
AGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAA
+
/F,$+)<H1=$B:@4@$:G'F369B5B4'.76190E4@!61-2('?*@6%3081#>48D<!78/!@C*:H;::G-2+E:<C/@&%?G"@/&4B(0?#.C'HF6H@#$B#25A(".9.A79*<788%73F1#(&.@G85=.,;@?G;4@)<46F'8@+6DF+@#$*E4E%E"*&$G*F*0G+09
@r9051
GAAAACAGACAGGTTTATTNAGCTTTCCCTTTATTTTTGCTGCGGNAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATNCCCCTAATTCGATGAAGATTCTTGCTCNATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTC
+
#()*(#+')%)'&""+#&*%*&%$*)$*&%)$*(")($#%*!##**"%"%)*&#$'")+&"$+#%&+'!)#"$)!'!&($$$%)#))#(")))!##$!)))%$')'$#!%($!&%&&$'&(&""!&'*$(&$(**(%%$"(#"$+++&$!%#%%&$%'%(+&&&'#$+(+$*)&*#("$**)(($"(+$*''!%)'%$
@r9052
TGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGCGAGGTGTTTTTACTTGAAGTGACAAATT
+
#5$@@)8&:5/5C5@0/$"6("5H19@!&?0:018--G?@&=AB5(C;0@*:95=<"?:="2):4))(E)"
@r9053
NACTTNTNTNTNANAAANNNTGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTNTG
+
#'($*)*%"'&##"&%*$%"+)++%'&&#%+#!#")%"))')+)$'""+)!&"&+*"!()!#&)
@r9054
CCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATCAAAAAAC
+
,.EBEA+)!'GBG#+"DD50CC/(*(1,#/1G:$C.1B)8C>#(<@3FF)).=3,<77-39"H2"@<FG(;?%*.8!9&(&)/1D37E?97!H249H/FAE!F'<70&%9FF8
@r9055
GCANGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCC
+
&)$*++($+%)*$%!%#(&&&'&!'#()*%#&##%#(!$%#!(+!!+(!+!'!')$*('#*#$$!$"&)$#%$&+(##!$*$*$"!!#$$$&+$#'#")**!%(&"+(!%)!'%%+)&*+&()("+(*)'!$*"&(!!$(#!$"!%("!)!!&!+%))+
@r9056
TATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATNCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAAT
+
C1(#E$CD6'(((3'G/,A91%G0GBE7/H"8370E#E45C38'1+,E%<,35:"G/CA<=0+D)E#/;*5D06C5B3A$<5A30!.;,44.1#H=*%@#;,<&).$A%4!/EED>=.AD?687$9+FFF4E=7#:'H;#.;!H10@().
@r9057
AGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGNAGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGANAGAAAAGAAGTGAGCTGCGTC
+
"7@5C(2=@&B0GB6D0+C%+GG+,5)E1447(=36:,D:/%>9?=91<D0$'6B!D4+6/?A!D::H=7.C7$'*A(G*E&C)B)?@2><.E34>G.<BB1*-3?=6$G!@B9G6&HG75A=;8-
@r9058
ATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGGAATGGCGTACCNTCGCGGCAGATATAATGGCGGTGCGTTNACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCNTGGTTCA
+
A"E-2-=9972=-=&+<19E7F5F'>%@;(G-F8/08@4>2@G&+*(@#A,&0*""<@:H)*&0!9HC/A50>>'+6G,*H>#3391:65;5<H.9:13071>C.@63%,%A@-%>7.@3.)%@<')>*?)4@6&HE9G4-)B(!B3$30@";
@r9059
CCAATTTTCGCCTCCCACGTCTCACCGAGCGTGGTGTTTNCGAAGGTTTTACGTTTTCCGGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTTCACCCAGGTGGTGAACGGGCTGTACGCTGTCCTGATGTGAAAGG
+
"%5)5B(<A9.,=;>FACBC<02,%$9'!3F41>@H,?%=(C3@.79GF73:#/-,:7-<D?!.*+?4C7#H/$EG5-<9/5/@F$5G*55?9"F)4DE*A%,*A<).GE=4'A=#D(4@#)@=864$D"8>A+%=7=H)E<
@r9060
NNATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGA
+
&/)'03$(#5E2'4<-$7#G@BF('3,?@%H&8"(?$.@#13-6
@r9061
GGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAANTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGNAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTG
+
A:"E,3</?)G?)@;?!G#,CB%>(#0+:$$27#A%>8#'&!5HG@8#%E);"3.<2,?-;>54.;?DCF?/G#9:A/2*-$0(6<.0@,4G.A,,G<&9AA-%1D3!!A(.=);2A9>&",,>+B;!!A:,>%3G#9)3?):';,!;F:%-213HF%11=3>?CB-2#<70//
@r9062
CCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCG
+
CC=+B*BG1A=1)69+*9:E55E;"1?38'1D9$!,E$"<04:50FG:H%A:!A$2@,$=.B?4*-6$*-BH;"H"
@r9063
TTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTG
+
97,0=A@%4)+57.2-860,EGHG<8;79-'C5+,387C0.G'@ED.8>H0H=#H2=&2""/G)<B4!61(0&&!=D48,)C;8>8-@$("1
@r9064
TGGAANGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTNCGCTTTGG
+
+*#+*&&(#&(!!'!$"!*)"(&%'+%)$"(!&%)%*+!''*$+&*)("$!$)%!$+!(%*(
@r9065
ATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACG
+
G$>+4H&F,@$,G<&G!!*#@8G/HA.9)D9G)5(.>BC7=B;/)$37;:B??)/!1A.->")G.'?D;0E/C&%<GD$!(CF,)-B!-$+3EG!1C@8".@'";&<4;;C?@4997
@r9066
TCACGCTTTCTGAACTNTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCAT
+
8#'HE>71&7?2>&;+/);EH;%*8E;"C&:@%<=H85)";D6+&'F1,-?$/)H%"@*94(%.!G-&?E$!=>:"+,'+)49%3!'@A'!C&&%)"5';'*4:@+7*#;:,/<G*&3//DF<F<*G!0>-E+$*+/<10.:5A?!AD/G%.3;((%H+?'G5&
@r9067
GTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACG
+
GC&9!:;1!BG%$.-B(**7>F81:.1?;29;26A!BE3,GG&=6;G?2&&52?>-%
@r9068
TNTTTTTCACTTCCNTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCNCCGGCGGAGTCTGCTCCTNCNCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTATTTAAGCCATCCACCGGACCNTCAATCGGCCCTTCGCTGATNGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATCCTTACTGCTT
+
!!%#*+&#'*$$"+)$$+$"'$$+&(*#"$!#''%'$!$#+##'$&))(""''#!!$'("$&"#!!'+'#'%*+"!%)&&(+!%('*$+%!&'%%%*$''('&'!#")!!*)"(#(&'!$%!("$&&'((&#+&+()!''(*$%*%)!&(%")#)$#'%'+$("&&'"$#)!'%+"!!*!!)!"%##$!($)#!$$%)&+%%(+!*"%%!'$'%&)"$##)!*&"$$%(%!(!"&+!""##(&"'*#!*+"()&!!'$"#"!(!!"#%"&$#''!
@r9069
TTACCACGAANCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATC
+
46&8*;;1G*;;A)7@1":E?/G#'+21#*CA=4=AG$*A:G+HE43BD78F-78G
@r9070
CNANNANTNTTGNAGGCTCAAGAGGGTGTGTCNTGTCGTAGGTAAATAACTGACGTGGCGAGCTTAATATTCTATATTGTTGTTCTTTCTG
+
!!)%!&)%#)&)&++#)!#($#!(&($$(#!%&+$!&%%*"'))(%$+$$"$%**$%('!$%'%$+'"!"("()'()+(!(#$!(#*%"$'
@r9071
NCCCAGCNAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGCCTCCTCCACAGAGAAACAAT
+
"D/0)4-DD8>3GHD1H8H+A.1H.=D'=2FA0?<&02#AD4(5G9G>0-F3/7G!G9%105FED
@r9072
ACGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGAC
+
!/"AD)(4,79&4E;C86%A><668,>10=35E1%8FA@2E1,0(/792*-1&$
@r9073
CAGCAGCAGAGCGATACCGAAGCNTCACGGCTGAAATATACCGAAGAGGCGCAGAAGG
+
@G@4+0-!1"@*).5<(<GH:G,41!5H5>)6=%7%GH/>'.?H-ECHC0,,?);:8E
@r9074
ACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTT
+
-8G44A&>:7>E6A//E:HD@4=/3.""=C23A6E&*)0#6B'3&10>5+A*8<"@0/"F6F@7?A092!.*2C?(>*7(@?-&:7::&
@r9075
NNGACGTTCCCATGTCCCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTG
+
(!&$+$!'")*%)%"+*#(#$'!#))&$'!"$)!#*#('')*%$%&*+%+%!!'+"+&*+'&&+#$$#*+#"!$!"$%%#(!"'**%*%)!''+++#(%'(%)#(*$*)(#$)("!#&#"%*&*+#)''+&!'!+$+(#'#""!%'")(+%*+"'#'+(&$!*%$+&*%)#&'&$&)!"'%&'('+)*%*)!($)"$('"$"(&#'"*#$"#+'''(#)#!$"'$#'+&&
@r9076
CATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGNGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCNCCATCGTGT
+
:>?3-#=9!2<>./:=%%9?EE@>(4(7#%%G1AF(E35G$-#-F)CH:$&5.B&<6F";DD1F7.?A5H7$7?GG/*.6/;#1779C=BA!)(#+3=38&05)7&.0"G)7/;8-#:,H!G/;&?A)7/"30%<#F0<91@GDG.$7E!%1>:5/C4)5+0>;+:>3#7(9#!>483+9!*F</3173#>$E-CC>/&6$)4:E9@,-,!<0-,&&4@/A5*5G'B$F@:,..
@r9077
CGGAACGATGCCCTTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGTTTAAGGACGTACTGGTTGGAAACGATCAGTAATGCGATGAACTGCGCATCGCGGGCATCACCTCTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGANACGTTCAGC
+
D?DA,>,-D5F.)?,C1;#>/=2/H6B2:;&HB6)><F39C3-@/2A-?(!1E!:<2B8&H@>)?7A16//$!3>>+2%3H-G7&9-;G!-98<<*F$C)?AH(0.F;?2@4E:>3/+.6:A>$C5<#8#+%-5<:CC,CC8+0@#;G4/F*%,98+8"$*-H?5C6%GGG/8<H/A>90(H+/G)?+D'
@r9078
CATTACAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGT
+
20?&FE:+G10.6('-H)$FHF9<!EABE>-,(1/?<#G6C9H=B%%62%.A5+3+'15$='?'/&?BD1*&-%'5G?"2E'
@r9079
AGCAGCATCAGCGGTGCTGCCTGTATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCA
+
88E9'<1@B;?<0C5?>4"9+&*97!7)>F(C40>HG%>31;&52E(0!HG-ED#&$<1/E%4);
@r9080
AAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCA
+
953:43&$F5?93*F*9E?ED%+313G;.5%:4@"417G),;A5G71G07,97>C&>$H>348A.#.HB&G@B'2F6!8H(<D>
@r9081
CACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTG
+
@CEA;(*;475?)8C>;#-A-!69<.(1<,1*,-%/4E7%H/
@r9082
CTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTA
+
7@#7?C034/%'(?&#4:*A%6(-@?72,>#8:861'8%=
@r9083
TNNTNNTNNGCCGGAAGGCGNNANCNCACCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTNGTGCATCGTCAGAACTGACACAGGCCGAAGCA
+
&'%#!'(*#*"#%#)'"'&#$%&$#)"'**+()"#'+!+(*+((%""#%)!'%%')$$!$+!)(%(+&"%&!"#+#%$$!+!*+"&#%(*!"$'#!"!*$)%&%%!!*')(&##$&)**"*+!""#!!#$'"!$%))"+"(!$*(!&#($))#'($#%%"*$'&%(*'"%+*
@r9084
GATGANTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTNTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCT
+
A?6FF=$553:?!B&&:654BEA(5%*0.8=5G(&)$@$-3#9H0?&#A.B1$*<<B)1*1&AE-6-C45)B9,D&A+,#H3,/H4;&!H@*&F#8'7')CH'@*=,7FD=<6',4C9!,E5$;16E:&."5C3)8',$G%*F@&/!/?,!D'2=E>3HAH2B@12:6?5F76?-D#9<;7
@r9085
CACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTAT
+
'C69079><>3"E*1?/)(<$.>E*A54+5)GF+:9C$:*=#:=G6&96+6
@r9086
GACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCCAAGACCTGCGAAATAGCAGAAGTGAGGCCCCATNACGTTCTCANTAAAAACCATTCC
+
,8)-?,.@C-.+&6D0+/+.@>0:%16)&$$-7?/#,G@%1?;7=*%;?B='0(<G8>(>DC(3(:'C$/=B7(9C=92.10-3+#+8!!1/F"!?/DA7$8"0-,&
@r9087
GAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACTATATACTAACTAACCGCAGAANGTTATTTCATACAACGTTTCTGCGGCATATCACAANACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCATGTGCAGNTGATGTATC
+
+&'!#$%$*#'!#"+%!%%)$"&%&"('%#+!"*"$'*%(")*)!$))!%$(#!)%!#)(#"%)$#'$&$(&)!()%#$"()#$$%(&#%%)""*$$&)+*%+'(%%)&&%'))#$%(*&#)#!%!!(*)%*'%*))%$&*!#*(*!'"(%"%%$()%#*%%#("!$"+&&"*$&)+$&$)$$"("#!+!)"
@r9088
CGCCCAGCCTTTCGGATCGAAAACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGG
+
8>26E;.A(-";8$FG<+B*@5DHE3!C542&.&C:"-3&B&*2)-85>C.'/FB)'-(/AB9<?)3C?7-A$+7*F
@r9089
TNANGNGTGAGTTCGCCAGGAATGATGGAAATGGTCAGGAAGGATGGCCTCTAATGGATGGTAGCGAAGGAATTAGAATTACCGATAT
+
)!&")&*%+%+#'(('&+%)!!'*#(+#"!)#+%&('+&("'!**(*!+"&%+$%!#%*)(&'&&'(()!%!*$+("(!%)&*!)*$+
@r9090
ATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAANGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAAAACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGAGATGAACAGATG
+
C2>$24)1><"80#-H:9;>(E@8$22;66.B*2D34HE66'#5%>A@+B2%24!43!*E?86"7%"#F.)+&G#G?"(?8!(1&,+775F@<:(ABB8?8B>712G7;';1@15%#H$&E1<+**A2@=9264B$%2%D/&=,,0H%@3-!F7/'C6)G!-69#9;H&A((5B?<.',D,6=GB?7)A+'G5-<'=44<,'.@;>.*=B3<9$H5,0D9@;G-*//!C5:/"4@&>:;4%>EG-!><56*D.C84F5"C(/5.B'B17&D/;<!*&'><G77%:"86H",=8B(#8;3>#,88'>*
@r9091
CCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGNTGTTATATGGCCTTCAGCTATTGCCACTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCNATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTT
+
E$?D5D?->73'9###->,A6=31,9392,-#.@EA=#)CC5:8@:$%$@(4G<'%=0,8-(@$"A+FC$&<F,)+:1!H9$F#'F)>C-'G=H$?&*=D)-DGC26+HA9'G)BF&F<(>29336A=.G376*H@':&;<;H11F-1?D,:B/5:9E-6816H@.:*:65$C2/(C#6E*3/&1:032-7<!1%C((A,@"=@3!)2@D">4:7+=-5G!
@r9092
TCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGT
+
A*(4GF>5.&2,9E3A5/'6,A"39=5G*57H$6@=4.A!-2E1F3?
@r9093
TGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCNTGAAGCGTTT
+
65')#2B3*'D#0-C?844+B*A0&AE8C%0?:/<97D9?D:83CD74*@@/G:E3@%,40D&C'F.#F-7H+47=3D(5;5)F4@<.<31$A
@r9094
CTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCACCCGGCAGTGAAGCCCAGAGATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACG
+
DHF2#/&!1-<@@,5.,GB$94FH'1)(/FE%$8.+6?91,$%4"=#<+!-<)B!<F*?09--=$+?@$D?;7B)/6/019)4$>!$33DBF?B>@B>2C<%7+13<%$<2C#"42)9E&+,7<$/D70H"E-:,D).70.A+@%C61")''&)""%F!AAE1G,(!4/=3A8D;H(0-:CE:-4>F@4B?5F'"@<&21,(9!%399-)4.(1+"!<&G">,6F'5'2'/,$1("C%#E4!581GC6
@r9095
NTGACGNNTGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGNTTTTGTANACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTG
+
&&"('')$&"+!!'$**&"$(&'"#&#*&%#!'#%'!"(#((#%'#$*)"(*"(+!+$$!%%%**&%'&(#%)#*()+%*')'%$*%"!!$$%$$%""
@r9096
AGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACGTAACGGTGTGACCGTCACGCTTTNTGAACTGTCAGCCCTGCAGCGCAT
+
(<'37(:+9F?2:DC8$-)"C&7?2%<(2-75H='92D8*16,.B29)EC$9)*#'C7=()7>*E72='E%'&:A4:"3:A4"@3
@r9097
CNCAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCT
+
*!(%++#)&&$%$(!!*++#+*&"+++!$!))&)$$*%*)#''!)'$"!"&()*'**
@r9098
TCAACNGCNTAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAANTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCG
+
""("(%*$"$%+&#!)$"!(''""!!&&+"(%)+)&)#*+)!"'*%%)%+*#'((!()&'(&'#!##(+#'!***$#!'')**%"+&(!!#&!"*!$+#%$"+&+*&!!"$*)$
@r9099
ANTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAANAGAATAAACACTGCACTGTGTATTCATTCAACGAGTGAATACACGGAGCAATGTCNCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGNGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCA
+
()7'E18D+AF7*@!5.#;@95,7E!2E+@1DB*HA17745(-.D!4%">!:7?".25:+#;!-588=613?4#=;*/4(+D&!/;<>0$3;7H11=:9C!>B(E@,0#HA'>8?$'A<->2;:%'14"A@"C?D7E9GEDB0H0?!(9>2=8D+08BB+*H2#.-5GB+#B8<2(,?4;D.893BH)H#2C>:=C'&=!>G19#'=?FGF1&9BE-H%*7<&/,9?.,!HE)/2BH
@r9100
CCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCG
+
A&A,(F$B=(2%">@E'21A'<>:1!8HB0?!,>,6G8#BAG$D2A,@)D6F5E;)43)1D41$?A="5.:#7,D&<E/'B<D#&@/*)+,=3&B
@r9101
GCCGGTCCCGCCCGCCTGGGCGGCTGCAGCATTTNAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGNAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTA
+
1"0<,D&AD31D<C(',<>$EA&+D*A,"0/E2'666HA#B*20'-'19B<+*)?7))HF>,,$)0'E85&24@(9#35F35C/H.5%8+,<59%@+#(++/'>B8,11$(CAD"C,G&AC.,&45B31E'#'2*.904F./2G64F9
@r9102
AGCGTCGTAATTTTCTATCNTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCANTGATACATAACTCTTTTCCAANAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAANTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTATTCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGNTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTCCTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCAT
+
7'/#%=-'!=-&C=>&+.326>;&%=FA-$E;DF&19?'1G*6&.F!H2!(%#5368H>1F#8?1H<C1EE=-2!9@+D%G'39?(#4)+/(<("99G#8'5B:D54-&+":+-C7/)&#9+?=*2#>--<@D?@?;2<B$04;F@<D#3#D$('B*=8>9)E@4-G;$G$H<<3FEC7E@5#@%15%?>&DB$9%C<A-&+20F0@1#!>B=0//;/>;G.#>-749G'.G;%>B*$8%58%'26+#'$B)46H4'!7-*)037DAE972C82=5/#-$4EB46:2%=30&"93"&"/5>/</3%*,B60#.7/A,"55&*-E8H7?-)<6E#.(-$BB2>D0>=+'$.;3@C9=AD0$E!@0<+'F-3H8"$9'&F@*)"8)487::@;,#2,C:'.3%9:,F$$(,F>%H2-+700',"CH5G593D(,!3.8H.1,F'/DF-+>'8,9G#H6G"8#597E@9F<3;2;+FHC!>8=H>%.65>4678%:'/5)&FH'=??!B:D=12/++0!@6?D
@r9103
GCTATCACGTTGTTAACTTCTGAAGCGGTGATGACGCCNAACCGGAATTTGTGCC
+
E3G(40//F5=@@H05#.HGC6;@>=+/<24=-HD!*&<;913*DD5!-,D*C<;
@r9104
CACTGGATAACATGGTTGCCCAGGGCAATGTTCNGCCTGTTCTGTACGGGTAAATGCGCGTGGGGTCACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCATAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGATACCCCGCGCGAA
+
/?B<C!(:$1@H/13+98-12@959?!--%$C="E*;+3E(E(6-,53:!=4+7$&$$06*38+*!D)#@126A%!D5#1C;F-6/CB?>7'4+@!9-%)/F77A5<99-@,F2@D*>FG'G,1B)8#8@6HE%!C;D>&48:H5(7'%4FH?)9E&C#@&5;?CE9G3(H1!5+2G;GF+'D?03DD6+6.AFB.E<:G:,!D&<,49/H#((H@7+<&=6*9G1:?7;1&B%0;
@r9105
TTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTGTGATTATTCAT
+
6#=4,F,>-0,"G:/<B'"-C>=3H<HCE$@92D1-CD=",4EHG@>.1G-99>&&C!(1@(5
@r9106
GCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGNAGCGATGT
+
;,?8>90>%*98EG'AGB(3?%*>"==B!$)8!H"GH7C":DFB,<.3$F"&:9%
@r9107
GCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCNAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCNGCACTCTGGCGACACTCCTTAAAAA
+
D#HB2+/??C:8#70?@708AH6?3H;=;2+.E"<A"5H6(=.:H#H)7+4*<H05)6C(*:)8A(1)$':$.$D&FGB6+2#8GF"E"H:40*"$$!:H#+)!H7?E3*7@($E8#?B'(E08#HH&1'78D:/D')DB3$>@D6@>7<F$*;)B,)";C:!<F3D497:<4(*G9)H:6CH4
@r9108
CNANNCGTGACCCCATNCGCANNNGCCNGTAGNANANAGGCAGAACATTGCCCTGGGCAACCATGTTATCCANTGAGNAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGT
+
''*"!&)()'#%"#%%'#*&(!'!")*"()*#!$$')!*$$+)+'+$*%$)(*)++$&"%&'#'#$#*+')"!!!$+%!$'+#!*)&$#(%&)"$%&$$$%")+("!'+$%(+**)
@r9109
TAAATTCACTNAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCNCTCTGC
+
34AEG"@C;A'1<.":FG%.-H'9"36++F5",7BC&?"60C@G+.4!):=H-=3<$:/<5#-43=)=0(!'';G$<<=HG30B6B93+B0+),+74A,3B=;&.8&7!B83;:/7;5F3*8D7#E%9+G;5/H2/H=,.>F.969-;'=/'E$/D-<%%F9$@HG?<='?
@r9110
TGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCAC
+
G5:,-&44&G<+H'9$,-9,..F.CA>@$'4:>@?E*";-%&-)71:"7
@r9111
TGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAA
+
H.>"7AE#F(2!3<!D609/F(BB6<=D3G*!$17@6'*$:4!+8C8):H*8/@EA+.$6@:',"?;"EG<B-?>E3",&*0?)F5HA'FD/%0F5/2CF=1-1;'692*'6.?#4"((9C>=)B7EA*/:5D=!>9C=)4H%560%?)=(6H)"*0(*C?1,A"7;(!)/H,:A(51D!6/%79%:)/
@r9112
CGGCCTGAATGGNTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTC
+
3+17++4EB;:)F);2%E4%6A/3FB::<'*D0<<63/A.;/$!625'%><-)8#90/C3-)&!"15*"<58*%.2%@+;C!3653'5#'7$2:'-F(=H9/B)'"F:+9!2EB8&%=?2=<;A41$+(CB("AHA=%/.A"2+F')(;6?F07)B)H"G0-A21,%#8&063;E,)+60=D"<DF%%
@r9113
NATGNCTCTCNCNNNNCNCCATCCCNNNGGGANTNNCGNNTTNNNNNANNANCGANNNNGNCNACAGGNGCNNCT
+
##$#"$$$$"!#"!$#$#$$""$#$#$!!"$$$$!#"!"#"#"##!!!!!##$##"!#!$#!##$$!#!!$$$$$
@r9114
ANAAATTCTGGCTAAAGCTCTTGCCCATAAANCAGATGAACTTCCGTTAATCAGCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACNCCGATTATCCCTTTGACGAATACGNGTTTGTAAAGCCAGTTGATCATCNGCAGGTAAT
+
)$%(+"&&&(+!+$#''''+%&%&$)"'(($+"*)(&(#+#'*!'#$!*$*!#!#'(!#""!++&!&&$&&#)!))'(#$(+&'$($*&"$+!$&**+"$**$&+#*'!"*&!&#'&"%'$%*"&%!('%!)"%#!+"!)+**'#(#)+!"'$
@r9115
ATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATC
+
CB4"608%<;)")014">*">B966-")07D2.A!F'%2-H+,'/08
@r9116
GTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGA
+
/H81(0.605040''0.6'+4G$F?*;F*12,@$//+B&#G26E,&'2#A/&1HE?;520-'8@/D98=A>HB*B
@r9117
GTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTNNTTTCATCTCAC
+
4G=6<F$+!3!%C".0HB#<<331!6F)+$+1BBDE0?-(;#/'2*%93=
@r9118
CGGCAAAGACAAAAACGGCAATACACACATTACGCATCGTTCATCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCNGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGGCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCNTCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGC
+
A?>'6E:G%-E0F,E6'8.1<7#GC/&+!:*HG-4F!;AFB!#+9G:F#0'$(H10:+G*?E%*FE"0?+"6-GF6A,4+)$F<5&F6(322>(=@!!,>58DAB<C,>77@#!'97452@38:#"DE:A(-1-$:@#;0&7>##C.)C2,F8>92,<1C1E,*&&:;#-"C.;F3-H#5@DC;5HA*G&9D)-GH8B36$2"B,':68A$?.!!='3*8=B'@>3B34@#&*C,*#'@)*!4B"C>5%,(&A"AE,867)>2(>-5-0<=70?"66!D,.H,H09+C$(E4??"<E.<<A-?;EC5:.+G>@G37!@!97;:9C4%G%;61;#GEEB-H&0:/,(7CC&/*5+EE(:"3C/@/?AF2@F$%-:1F6:;,59."E"GGA<GG=F3A"A2#E)3%';$;0-,CEB?4@+58<G1>(!(*<H>+A+FD%H$2.?($/+,)><C*/A2':&4-,*@7!*E?;BCC%#GF9C
@r9119
GGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTNAACCTGTTCCATCGTGGTCATCCCNTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAG
+
1C769H;EC+G1:,?:2$4>BA2&1%0G5-"529BDE:7#/;D;.DE83B%98>#H+H7":-!A=25?7+G70"FF!/B(/1F&/&G?',1'%+()G)@6B/3CD>C?(H.7E952G"C83)+/%%?@7A1D2EC3/?*H*85#!E$-&=%'8@56>H2$7=,&?(.53
@r9120
ACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTANCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCA
+
BD<@,#D'/H&78G*01/243CC/"+6':,*:?D=GA#G?7D@:5=(@8!>23G)D&+9B5&AH'/%>(-'5/)5%A<."H?-1<?396$CD2B%34:-$$
@r9121
CACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAG
+
9%:2>?32F@4HEF#73G1#@GH+9<@%$,0*<9>68$F%6?*/GB68*"GF23!76AG-?G,2>*,:E5&7#,!+4E*018=?<1>F>95E8C#/*>B!10H3-E.%HAE:":>/9#,('&8,.@C4!,/F1A;&F!B8GG96+;
@r9122
TGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCT
+
)G@EFGBD4G!!4G(D@-8H.,4F50<%4E2@D>H3@2415
@r9123
AAATTGGGNTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAAAAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGATTTATAAACCTTCATGGAATATTTGTATGC
+
&/>E-.6-5?","A!@27-'(H>(2!79")$B0*@<C+1B$;-#=F:!7+08%$,F5>E0@$509H>H(,%A4$7.8GHE&)4>H:)3!-D0=A%CB9$:-86:=5H6C;-,-35(H;:FE@!6=121B1?%<!.'CD85@0$&;!=/?5!$;C:'85:+/A
@r9124
CTCGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGAGGCT
+
$!"')($"(+&#&%!#)!(+(&!#('(%"'%#(+*#'%+"&+(#!!$&!%
@r9125
TGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCATACCGGCAGAGACACGAAACGCCG
+
FAH+0&""C4,"-"/=DF,;D;(1"4<)#8?-H*-<>%F%>&#4C6>-D#5&5$/D5>@!21)/D5GCFE5@#:C5!H:4*=+.DE&;6&BG:DH)2(>?4FH<H3"&-B7A5C6'8=ED(=1+3.E!C71$B6/H45=?/'9!-5)5=B>4$"-:"/7F'BA+
@r9126
ACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTNGCA
+
B;8H(/G95GH<.1:(?.'*D@-'(?32&+60>6.?:C0?9!037*&.#/5+B6=CF!961
@r9127
GCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGT
+
42CC..-?2<&F0$&9!$G'E2&50-<1(-71+)/.>'2"8?,150*'+;-CBC2(=="=E6H2>72@2.=8D$*B=?*"2;>";3/E+3D0!3>-1)FC;A"?9++158
@r9128
TNGTNATATCGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAANTCACATCGTCACCCATTGGATTGTTTATTTGTAAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGA
+
'***#"(%&$+#(+"")((&$#&(%)&$&+!)"%'!!*+'()&**"$%#)!&++"##))"#$#%+%')+'!!*+"&+$!$$#($&&%%&$%'+(&"'#+&*""(%#$!"$*+)!&((()&!!*#(!%'%#"#"*##&++%()"'!)"'+"'"(!*$!$()&)!))''$('")$#*#+*+%()$*)%(%+%"(&+"+&"'()(&%
@r9129
GAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGNACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTANGACTCTGCCGCCGTCATAAAATGGTATNCCGAAAGGGATNCTGAAATT
+
):8?H)<"(<7=C#)71@;1(-$B=4/B4;>F++H(A*&*41B7<?"9D%>&*(.&A-$/7C589?/,1@3$92$8''0$FG@E,58)?;>(B1B667!#+='0$2:7>EDA2%BC'@G<*(,%>@1G;(G+0;;>"/5B#HGGG'D6'*9#EBD51/G#=.#*#.D>9+?,E2@7@*49
@r9130
NNTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGA
+
!!4+E(1),>2'!0H#H.'.,-59:3'!7<3@@6E"F;>:B4B%HC/#%C815'EG?FBA*A'#F7FH8C""%95'%-13H)+=#="1)8H?=@.90?#1>/+#68G2
@r9131
AGCCTATCCNGTCGCAGTTCCCCCNGGCACTGCGGGCTTCCTGAAAACTGTTCTTAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCNTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGNACTGGCCCGNGCCGTCGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCAT
+
5C0E?,54G$82'+BF9B:>E=7:8.B1+28C,B;$0D,,2&C+!EA7"2*<*/-D*&9;4#$"GG!A4%B>.,B0,B(:=1&.8+%2&+:E<2/<!>2.&;%.7-#770B4$(,0=#E30H@,605G61A)011@""$89#F)FB1@",%/C8/;>/@,FG5=292+7D4E.%4D=(%6(EC;<B%?($+3HB.45(,4E?&C0=H/+@2?;CG&,HB3<H@=:@=!21F9*>(6<3"-*-(%'
@r9132
NNANNNTAGANNNTGCNNNTATCTCCGAGANGTNNNTNNTNNCNNTTNNGCNNGGCNNG
+
$#$"$$"#!!#"#!#"#$#$$#"!#$!###!$#!"!""!!""!$"$#$!""!#$#"#""
@r9133
GCTGAGTGCGGTTTTACCGCATACCAATAACGCTTNACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGC
+
#FAA?BA?4!C0?<.A/%97A3H.?)37F+"8-6H;=$<#%'&7!5B257>!4%!GD+A>G+8.8@;4'C,$89F(*6D9;7$G$'E3/5HHB&.4#$'F21
@r9134
CGGCCAGTACAAAAGCGNTGTACGCAATCTGGGTATTGTTTGTTCNCCTGAGCGCGGTTGGTGCTGTTGGCGTT
+
+?.?/93&4<,<65/$G@-C7H@!%%1(8B49+?G.C$.@967',,(5D<=,D%%,'E>.8;21'3E6(=A6$,
@r9135
CTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGG
+
FF@.EB:B>,?-,958D"7='7=B&"1A8<.$55@(G$B;5E0B6)'/"6589"45CH$9E7GH#95%0<"AE'2=43(A0+#6717$B("8A'!F
@r9136
NCCNTTNTNCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCATGC
+
!'&*')%!#%%+%+%!&$'!%%&+*#)'+*)(+$%&)#*(("!"!())$%+!%&%"%+('"(+'#!&))(##')
@r9137
ACNANCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGTTCTGCAGCGTGTCGANCATCTTCATCTGCTCCATCACGCTGT
+
"%!#(*+(#%&$'!$$'+#&%&*!$$'')"$('$#!*+'&%$*!*!')"#)'$'*!#!$("''$%'%""+*!%&&%*&&(&'()+!%))&)&#)*$!#")!(#%!!&"!+%#!)'"%%*#)))'!"#)*%%$"%!*""$++!$$%*!'%"$)#%)"%!$!#'#
@r9138
CCCGCAACTGGCGCTGGGGAACTACAGGCTGAAAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCAC
+
'%'&#+(#%&+&%!*(%''&%##)"%%#!"!$#+(#(')"##!#"+#)%&(*%#+##"+&%#%!%$%#"**)+&)&'!!!!+!')%*$!)#$+&!%)(#&)
@r9139
TCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGT
+
G8BG!-/A*61"%"G#.1-4:-:F"B*@>1E+'(:./@BGA:/=/1?.51%/%28A4!8(3G(-!2)$03-GEDHAG4D$G+=#.8.G$H"C(
@r9140
NCGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGG
+
$>C1*H33#G;@#FGF&%0*$!DF$</63A<8H3(F.(7?(9;?@=D,21,$0&*2(!2@:@A+$
@r9141
CCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAANCTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGNAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGT
+
?)21A.HAA71-%@%<<8#)*&&&>5@*EDE=?+DG!<A#4'E@2G%BC654DB@543A)>@+<5,(-#68BB!H0)38%):/-,A(..-7,E.:C3BE=BEF+(599F./)C.3)#G$87@E=,)-)&79/<(>'368<)66/&,211)>-:*39;@;3.B0:(*
@r9142
CTGGNAAAGGAAAAGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGNTTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCC
+
*%*+%*+"#("&%%+$('**%++#'%)+##!'&&)(($+$&'$++#$&*)'"%#$$#%%*#+++$&'"((""!!+$)%"!))))%""#+'#$%(**'&&**)'&(*!++$)+%'&%&!)'!"#(
@r9143
ANCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAG
+
)$7?#BAA-=#(!@@F%$5<DG5(>=G;##>7:2?05<7?2.4&..!
@r9144
ACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCG
+
2C(*32!A,,3)-D1%F8<<@#5-9@/394?!.6@$A89;!,B4#@7)6C-E"FF8CE/"/?)1(H
@r9145
TACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATNGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGANCAAAGACGAAAACTTGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATC
+
C)+?2E79C2$H9=>2<5$>"1*4/8:EG,*,1#:<G)H;/F=/D4=,(#<4#2*HC.=!*/)."AA048?@@9::,8:;5G'-@7H0/EDB7$-@9A<"F8/&7+F3413!@8>!)G1)8:B#?((65A2;4#%:H?')!9>(;E%9D7G?C!2B/B>23E4H>>-8>!@A/7=H$@&EC?E?B$D>=0++B4;>*F,.):<"B3>5;28:&5B9*B,:*A!17*@@30=422,E8)D0D/FDF@8#27&A#.,G7$>G#($DC8*@6G!B%3("2084&H0C8E%;>7416A.69#,)/7?=9/G('D67<0.$==.275AF')1!6-E;//*.C'4"!374<>$/A6/0':'>5#/AA&)'1*7/.4>HA-@@&4D>4.);D.FE##*245,8C@"'45=";*%4D5E5!63A:)!F.,,$,>&C3B08EB:@;
@r9146
TACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACNCAATCTCACTTCTAAGTGACGGCTGCATACTAACCGCGTATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCAGACTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTGCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCANACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCA
+
92=!>-)E$%;B.>>E;+H57GD=-5%''2:93B;D7(D<3*&)A1C<.>:/9/20&<$">.A>@$-+,4A21%,:$HB+?'F>@G<8>$4>(%/;=8)29H358G#:?"8"&86%'1?2:"/H93%++&D4GA<)G+C2-95A((2(3A%?,"%4.>+&,>GA+/052:9)#>6!"!(E0!"1*)-5'+1E4GAB&30@(?)'(<D0".+@,-1'.>CBF?5?$=7'!1>3)5896@?)C@8-11'4."+HE;$.;@2(B*C9A,4-)(?,@--96?EH9D3E103E91>#8F/;*(.:HE3.E@6%#"1431@663&)AC!%->@AG>,A?$3*B579>)*")G,'HA,%C'H=#;@A8,+-1486&,H(0>(1&C/6;:2(27/-5?2-%GF$!FDD,2,6?HD3%$7CF=!&2-=/%C?0?0G#1,3B40'/&/+(H<!2/#1F$%,"'G:%3@"1H.#.E)7EH+"5C,;&H%<
@r9147
ACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCNGGGAACGGGCGTTTTATTATAAAACAGTGAGGGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTNTGAGTCAT
+
;>G--.<-)-E%;&48?H;(:&1.(CH4AA2E)%E;)43-@FDC@CH62*2>D??G?8%24?-28>H-F?42;,FD#)#!<CH>)>+?GF+>;+=#$%-#*8"4=.E5!(3A#H*?*7/?=72.F4C>$7DAFH>9&3!-7D>"60::'#0!E#9#8@D01@,8B67=';".3/B'3"H3+G%>BG-)?<7*F-04!!'.!84>2=G=?;/@15H5>@C<<#5E=A#01>(90?#$7=.!'B7EEE3679@
@r9148
ANCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTAC
+
(#'G1(,>*GD&)#":$A,3,$9E>-<01A.0+DE$;/ED'@=BD
@r9149
CNGGTTNAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCNCACCT
+
)#D742(4A:7$%13F*=%$68!<3#?*&1@2*0FC2;2FEC:<;F31@CDA=96E'G2/=A?4':06-/@@A,?(40*D'G-5"#(!05#=608FH<0D%,HA%"4"
@r9150
NNGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAA
+
#!+*)!&%!(&"*&$$''"&!$"(*'%%*&)$!%())&*'+#&'"%#$(!+!#'+$)'!$("$!(%!*&'*&!!$#!$&&$&$!"
@r9151
CACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAA
+
9(@6A7&(;6-BADHC+3@*2:+HD)0$7/?='>:-1B'3-#>0-"@*'0>:'
@r9152
TGATGCTNAGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAA
+
7-H'G-D5B=(,A4.G&B<#?""-G:$+C=B)F)GC9A4A$<9@0%C6)-3E@%94$27,D0F=$)-%"96=E;+?-6%+B)B77F&5(90>6(.D594<-"D(,(G@-7-C765*"/@>A>'(D+9A;4.HH$(9+$%-."%>A>,?</@-%C-'11?;A(./6%@/)68G9D(4-@F/E/)1)2@:.0E&+4'E/9;!<;.F:2G@-&
@r9153
TGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTC
+
?E?=)2="+*5!3*268C%=B,*4H>)+88C19+,<;E9D$A896A1>A&8=2<C&;93)/&0@6.#4$(;C3)7)$*7'F+-.B6;'2D+>=*/
@r9154
NCCGCCACNTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCT
+
*<0;!B/D)3:90G9H"->)25?-#D*0"+=:9>6/DAG?';>:4
@r9155
ACGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATA
+
!25#1H&@2%-;9<'@4<083!@7%+G<30D(6%9C0E7=9$FH-()3*H7>C+5=.,.@C(B.:3'BG2:%
@r9156
ACGTCGGAGAGCCTTCCTGTTCAATANCATCATCAAAAGCAGCAANTTCATNATAACCCGCCACATCCACCGACTNTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTACTGAAACGCTTCNTGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGNCGGCTCAACGTGGGTTTTCA
+
@-8G)H#;)E!8.D1'H+6DFG=).),:/A'.)<1040H@87!"!C-:%B/G($C&B73%F3.;/)F:6:+=AEDAB/!.;@C%E$EH3%G-#5C)&C+:>=51*;D3!10.CA0F835=7!!#5@++25E'5&*?0,H2C;B3E3(?75&C'B&=/2'5'8:-G#*97%9'0,:H77=*'H59-D*F8"E8GFF:A1&2#8/0,9<!F.;;A/4F(@F!<-:==?H.0<A8)FE&'B*;
@r9157
NATAAAAANGATNATGCAAACTACGCGCCCTCGTATCACATGGAAGGAT
+
!)#*)'('"&%''#+&!$%+%"#(*#+)'&"+''*'%$&&)#%!"$+&(
@r9158
TNTCTTANTNCGTTACAGAGGCTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTANTGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAATGTTGACATGGTACGTTTACGGTGGGCTAT
+
!**''$*!)%''$%$+#)%%'!*$*($'(#%)&&%"$$$$!""#&)%*'$"'))(#%%!&$'%*#&%!*!*$!&"*&*+''*""($%)$"'!#$$$!+#$*+%&&$#")#!$"()&"!(#$"))('+)#"(#&'$$*!#'+*%!")&$(!()''!'%"'+(&&%*'##'!
@r9159
TGAGGAGGCTCACGGACGCGAAGAACAGGCACTGCTGGCAGAAACCCCCNGTATGACCGTG
+
926;*.)%B"48H1#5AG5=00-E;$.>%47:#F&)=%+=F%?8FG&#"(F83C2,B%6H.
@r9160
CAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGC
+
4.@#2F:7E5;9;<0+/%B5+,>+/@C1'0!(=>DF-?H7)29135,!02@%3&&'(?B9,A)13."F)14%;?E;.0#
@r9161
ATACACTNGCTCCTTTCANTCCGAACTTAGCTTTGATTTCTGCGATCTTCGNCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAANCGCATTGGCCCGCATGTACTGATGCAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCNACGGATAAGACTCCGC
+
BF7?7D!@016H7<3-/.5#1E(556#6C5-"$/6#-5-(&%%3)DA<(>/6!G@)(8CD'3(*<(&!4*%#@:=#0&DD=2,G!''B85,"71D7<A42&-D;F:"<B/?@$82"%:*<74(..76AD15&.GA.1'/,B+C<901*,:>!#>#H0C(?B.6!?+3++<90F/70-F4=!>=1=+;H<0E6-*GDH?=@98G5GC,DE"&HFA0/GE)&&=>!CF$21$+(8$,E-<E:<$G.=9!'&2?8)<'F")CB;+-!#3&%."&:6!
@r9162
NNCAGTCTTGCACNCAGNTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCGAGCAGAA
+
##"%)**$)(*(*%(%$+#"")'!&(!'((+#""$"*("&%&&'()*&+**"(&)&)&*)+*$)#
@r9163
AGNANNNACTANTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCNATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCNTTCGCCAGGCTTGGTGTACNATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTG
+
($"&!!%*%''&%'*+$&+&!!&"'#(#$*)$#(*(%#"*)&)+!"&'"&"'+$%(*#("+%'&$)%$"')#+"+$#*'&)+"&&+')(*(*$(&'##$*+*$'*(%)"#&(""#!'%&+#!%!)!((###&&+'#)!&$*)!'%$'*$'$#+$#+*$$!)$''#)!$'(#&&+%'&+"+&)#&)%$!%&%"+)++!$&+'&**)*&!!'+())')#*$*)+#'$!*+!#+'+%&"
@r9164
TCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTNGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCG
+
H%,AC3>:H@=5E0FAB4&>+G@G.!</(=3&;F?234"%7H!2!,9)#7/%;4#7H5-.@7.&0B9$5%B@.9D,@D+)%@30%>>6F@#(CA%%36&E=(+D8
@r9165
ACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGNCAACCACCAGGGAATAATCCTTCATATTATTATCGT
+
'F#20,$FDBD14;)E116,4A9#=F>5&7!C4*3H.29*0G/B.47;0@=1?1'85#.(.G3A$E35<,*,F>C
@r9166
TTTTGTTTGCCTCACGATCGCCCACAAAACACATAACCAATTGTAT
+
@CCF'F<(6D=5/81:.45+?HG&'A<("=C!+EC=$8!,2'@<4#
@r9167
TAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCANAAACCTGATTCCAATTTGAGCAAGGCTATGATACTCGTTCTTAACTCAACAG
+
+1$!+'F4"<)9(<*8B$53:?;+B+4+C1G'!'.*H8:>1*>F1*5-1>H@=FH3C#-;79?0HB;CH/G$@D>$;C:C1,2>0;$%6=7<:/
@r9168
CGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAG
+
4%*-)+>B2*B37!H%C61;4:*6F0@?A!/$7#?=>AC<-88"*D8";9'5('#A6(.B2=<8>/%9$0A*%)GE(@#;3"36<'$."781,=E683)4&'9E)&9DF">2-/'+C1,G,*$7&:!D/13#%8E:&A;H@"1?:;>1;7H*=>8!G&<)@(3"<,:-/"&$$-1+?55+1*,7=<H>(&G%+H86&))1'4B)8357A*.
@r9169
TGCGTTACCGAATGGATGGATGAATGCCGACGCGAACCANTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAA
+
+H4')B>-/57$0<9(;0E02<DG"@?@98/5@@+1;/GFC6%8%BDA0@C4>8/&3)G&$*;32.$/F!@G63A(!8<,22)098.BA@2&6
@r9170
GCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCNCCGAGTACGGCTGCAGCGCCCGCGTNCNG
+
+++$!$+(('+""&*+)+*+!*&''+""")&)&!)!")+*$"#($%"')")&("%''+)&+$$"#'%*#%'%($"'%&&$$)%*$'%('##*(%)&#
@r9171
CAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCC
+
@12EFG*A,72#:?>+0'+BE+>G<.0D'1E;,@0>&,<G;C!$,63E?)9G!F?ABB.:HC%;E;D8A;49<+,@,)G"A
@r9172
AATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTC
+
D",,?H%5/9295%FC8.)*><3%9-,>>"&$@93$+HHE)<*.0765/?@.?H4
@r9173
GGNGCNACANACNGTCNTTGATTNGNNNGTTGNNAATTNNTATCTCCCGAAAGAATCCGCATACCAGGAAGGNCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGC
+
%%!$)&)(*$%*&)$'$)*'!%("(!"#*%''$#&%'$!+$$"%#&'"*)!"%&#)')#%"*%#"$)((#$*())'""(+#')#+#&(*#!!*+%+%'&"'''"%"*)*)#$+$
@r9174
GCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACTGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCANAATCTCACCCTNCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCNCCGGCTCACCGGAGATATTCACGNAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGAGTCCGCTGGCGCACA
+
:H!EGH19@G-2&%2:55#5A.;(B'7*207>6/E%56#(.7@/0"C'"?/#(0(->EFH3/0.9&G=<0+-:.93)G7&=;>B;56>$'F!1C'3)=9@0""%A&-8EF1E;:-')$C:B8:>,20%=:<7C-4/4>3"8-&1*;.?18";<":GCF7$0F-')GA@!D::7GC=.+!=.=#.'C@&A*.+#D:05?<E43D8?"5160"C'?/HB8B5.G?$".3--$&G%%:@/+5B=/;"3(4#D'5E'>&A4?8@=<=(-G'8.
@r9175
GTTTCACTATGAGACCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATG
+
)C4:6=HH2(*8-*,F;.1FA2:(:D3G<+?<A:25')#1$F@09"G%#0+:D;8=,%7=,76%EG*98/&,(H9-4<=>5((6*'.>-A
@r9176
CACTGGCTTATTTGGTTGTGCTTACCCATCTCTCCGCNTCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAA
+
,9+"98&;&?;;'DA@.>/'"9&.;3D8$9<?#>,)"4BA"+)0:>/>21GDG0(1.0$ECE3)146HC!HB83(9A:#0>+<2*"%(E</9F,'H6'<
@r9177
CGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATNAATATGCAATGCTGTTGGGATGGCAAT
+
HG6A$?,7)A1"!/#F5+'D#9*F-.?)7@+E.5#8.A@8$/7*>#(2)-##!&<9,A=/3%C4>6'.:BC3A:5E=>13*A)'6
@r9178
GTTAATGGAAAGGNAGCCGCCNAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGCATTTGCTGCATTNATCCTTCGTGNTATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCCCGGAAAAACA
+
/,788.-"B5<747GF%)>@6<'H0D9&862.&D625"D$#5;AC;H4A>82(&AF326?@?/A#CC@99&934<1-$&D>&4;G#4$7%/52@A&"0&5:*4&,A%:::*?/$H7=*F5;'B55*A0G$A9308D&DD8H';;.:82./H9,)984HG,FC3!!2$5E)#+>)!-94/,E)!%!7+,<)CE'D51>F6D)-
@r9179
NCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTG
+
(4=#8.'3F&D'E&D)3.2)21<1&.6--=.CD+=B=352G$A;)(12A05)$3'+,)0::C!-9=C/<9(0'1+=EB.BA/!F.9%//6#14
@r9180
CCCAGAAGGGTGGGNATGGTGGGNGTTTTCATACATAAAATCCTGCAGGTCCNCTGCGTCGCTGTGTCA
+
+FE48AG7-*"D#@0$77/"904,$5)2)H87@D3<4$/B2*.B)46%+B3H6&%F1EE@*%@*+-152
@r9181
TCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTACCTGC
+
<H,''D!)F-*B%@!(&*B=A=B?">HA-;55F;:344<51=38?G3=17F;;$$:<=09AD(0.C"F13;?D$/9"B@;'D/78E%:1C(H/A,F4.;(#9F?F=-5A*A/;",0)>7)/
@r9182
CCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACCGGGTGTGGAAATCACGCTGATTTNCAACGGCAGCCATAAGGTGGATGGCAACCCCTACANCCATCTTCCGGATGACGTCCGGGAGCCACTGCAGTCCCGGATGNACG
+
'%+#!&&#'"''+"&#'%()&*'&)+&%+'&(*$+'*+*($))$!+&)((##!))&$&!*&(")(''%$*%!!&))($))!%')*%%!%*%(&*%&%)(!('(+#%&*)*&$'+)!"#$&#$(""())%+$&+&"*(#(%("(*(!'%#+!)(('"((+&#((&&(+"&#"$%$"$%"!#!$&+*!!%'#()')!
@r9183
GCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGC
+
'9(+99@5&%1,4@)>E;/BGBF!!/7FEF.#</6D,FEB>7!+*E"6D;*"+9GC6%B20*0-:+-9"
@r9184
TTGGCGGCAACCAGAACCTGGCTCAGTTTGCCTTCCTCNGTGTCCTCCATGCAGAGGCCAATACCCNCGACATAAT
+
D+=5:1?'&<,(",C,,$.C*G'810D1H*"#/'27)D>A:A+8/A11A,'D=#%D%<D=%,%!&=?3:431>9<,
@r9185
CAACTNGNGGNNANANTATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACA
+
&*!)(%#%)$"!)"($+*($%(#()%&(&*+%!"+*('&*#$+%+"*"$'%'%#!"'+*!'!$'"'*$%
@r9186
GAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGAT
+
?4H%79$F@9#,=3;G;0/&$*88F$G-H)H9686:C>'%.;59H>F;,4)*H3;#.<+#+F'!+;9@-*>,=$*(5$<.<+7.H-#4'&-:E>6@:8%0&-F9<F,C-E
@r9187
CGTTGGCNTNCNTTNTGGGGCGGCGATAATTCGTCGCATCCCGT
+
)#"&(*(!*")"($#+%&+)&(+())!+!##'+##%&*)$*"#'
@r9188
CACGGCNCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTANATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTG
+
%<C3!!2'&:C":"F*5,0:C"@!2B0*G52F/A9+'6,D+@/%;/F+G343;7)&D!//6:(:(@9*:A84&<H5D-B$4G1;!0+.F<G)!4?=.?$BH<':G02!92(D)?7D;>*<%@-8$3B=/8*$GG0?/=>B*6A5<!29>2F,'97-7/&H+
@r9189
GCCTCTTTGCCCGTCATACACTTGCTGCTTTCAGTCCGAACTTAGCTTTGATTT
+
FACH+=@%;=4:8H")'F;1E8:#G5>#):3&".5=8%/B:4<&0/=3;+@850
@r9190
GGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTC
+
H,:9/8"4.6&BB5F>+F?/A@3?$0?#9%$@BA.D*%D9"*-76H1H?1:;<?!E/;>*;>,7F7$!1,83FH>+'5'.67=-EE&0&$(<%+-G./=E=#H!?>9-,9$()=;0?;;93A(6.?$/F0?6%,-)@HC1C5HB>G@D!">$%$1A!8@E?+9,<?/*7')C<+37!E:+@)G:?:;"/%CE0;0/9@"C.5!E.#E8+G+$%8.:/1*0B!1").G2'589H:/;"'56-2&91.EA#>F2+4B5D=:3!!G);1%"D>982/?/<3$C57$8
@r9191
TGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCNATGGATGGTAGCGA
+
92'<DG4<9G@>>%!A<$4;3?%*$*H(C7#>;*241F@H+43=D6+G67<A=*4FB3,A+7H-
@r9192
ACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTC
+
<F:?3,<C.=F"(&''"*!B692'E-*B;BEG8GFFB88.H1B*3?:H5
@r9193
TTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTAT
+
,>#&?9!>?H-<;E(B#&EE#DH@EB5208'F,D&>5)786$/1+@
@r9194
ATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTT
+
4591#>>G!3:G*?*/4$#E5,=1:/=6"AC?;6@2=>497F/$5E'G?:F2-2:)D$6,&!%
@r9195
GCACAACNCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTANGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGG
+
&&+(%%++$%&$+"$+%!%&$!)")*&#!()(#)!""+&(#")((*+!'*)%##!"++(&*!!$$+($"#")&!*&$$$*)#$)!&(('((##++
@r9196
ANGACGCNNNCGNAGCGNAACNACGACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTG
+
&%$%*&*!&!$("$$((%(%*+%("$$!+$"!")#')'&%)%%+&$!$(!%$"%&+#$)"'*+%(%'$!"%++!)($$!*%$+))&%
@r9197
GAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTAC
+
);G>C&'#+->A-7&,!&0F%'G,?86A!68-#G%!*3?E>19"7B@/2H6"&(EC-!HA168)0BH-DB0G'G
@r9198
CCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGAT
+
/G%1*D&('(**<:81H&8C25),=<#<94B?;"BC!H)D(!2)9H9(,643"4)/9/%":-A%C2E0&3)7>&06"0&+&3DHB*FG28G:@&,2>"3=/
@r9199
CCNCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCNTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATGTCGCATAAATCACCAACTCGTTGCCCGGT
+
H'8!F/0)C,8GB!C?+?91#H>94)7$)(&"9$(+->?1)7"B=)#6#/GH,(2%;8!/@;D<!E?:14-9?:6E508%EF7=BE29$)$A!+*GG!4'"4G6&9G204%H/6".B6,F(2/<'@;???<+(+/B;D4*-*!H3(&BG59.*C5);?GE-8?,;GB</=:#0D,C+@:
@r9200
AGTACCTCATCTCCTGCGAAANCTTGACCTTTCTCTCCCATATTGCAGTC
+
&1E!9%',3B,HAC>7*@:,5AD!'E=&7>+CG*G/9;=@(=9>,/DB9C
@r9201
GCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTGTCCG
+
BC""&CE'=591-E>2C,'77"<)8'',/<.F:;.=@66=.=:AG8,5D+#,5E);%?
@r9202
ATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATANGCCGCAGCAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGGTGAGTATNGGTTTATTTGGCGATTATTATCTTCAGNAGAA
+
121H&!#(AE%&#'=?1*(8&@4.@3,H=HF-?9&F0GF3&F?6*'652?G$:+.A$,(:#;6+EF117%8A,+7=$(.2)6%;*$4A%-6%$<C'46..9G)&6.&36++E&806.!&8<*;9E-2%"4,,C*H%85C:'CD4E923DB95=,H*;/DH(A%07-=2&A92,<*7C4H2CA=+;=F
@r9203
AGANCGGNCTNAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAAGACTCA
+
!')!$'&*()!#+'%(&#$*%*())"'%!(*+$%&$''+$'$+'*%!)"')'(%#$)$%&%&*%'%*((+))(!%$#(*')'*)$%)*&)%
@r9204
TCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCNGCTCAATATTTTGTTTANACGCCGTGGTCAGCGGCACCGCCNTCGGGATTGNCACCACNTCAATGGGGTAA
+
069*-BG+B,A;678)84"H@9C3G(GB*00+D%6@/#-DDHD5GC-48G>4G*3!&7?$-H4C0*9:##7E,HF0)839->G'0"#2((&C2,,-:E73256./7%8@>=$?)=!.4?5%H>":>G<
@r9205
ATTGCAGTNATTGAGTTGCAGTTTTACCACTTTCCTGACA
+
H$.#F3$43FE8*:;4CFB-2+="4EED9(G,)G$-(E:1
@r9206
ANNGTCANCANTGCTGAGATAGCTGAAGAGATGGCATNTTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTCTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATT
+
'&!'%)%&*(#*+%$'&$(#$#"*)#"+%))+"$&!#*'"(!)*%%%"*#"#"#)&%()#*!$&)$"%)$*((&&%*'')'#+!'%#"%**#'!(*#*!%+"#)"$&'#!
@r9207
GTTCTCACCGAATGTCTCAANATCCGGACGGATAATATTTATTGCTTCTCTTGACCGT
+
1G&B21&5(9'?#?"58(C/::&4%02:<%3+4?!"4B<%G<5"2*:A99+B=A$GA=
@r9208
AATGGAAAAATNATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGG
+
2.-0@58&1A"-A'%:"!D/<@;GG0G4C'B4G,D5H>E&;G1;/!'G%@*'7%2=E,<"3/4&>+15$FBG(,E!BF;C)@5*@AGD=?A11
@r9209
GCTACTCGCTACTGCGCTGNCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATNGGGCAGAAGAAAACTGTCGAT
+
,4,6'>$0$529@9<%:3@.C)@(D)C)('H+</'A4FH5625'B=+?,'0D26@:H'<87/=;72F.+G.</H-BA$*0B8)G4H87?HC3/788A!51-AF-3=HA?B;/>.#9B'(3F2C=.F%/G'7#/F$(0<7+6..8")%8
@r9210
GAATAATTAAAACGATGCACNCAGGGTTTAGCGCGTACACG
+
2=$>3/9D)G;'AAG%"1B*,>)).A/GDAA1239<?*>>2
@r9211
CNTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAAAACGC
+
5=$A8#!4B3D")=5<..;/CD9/@51#H2>@,:=<HD*;?&<1*&71#453A@1HD%#"
@r9212
GATCNACGTAAGGCGTTCCTCGATATGCTNGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAG
+
#')&%+&#"*(##$##+"%'%%+*$!+'&"+&%%$'%+&"#$#%"$!&*#'&"'+'&((#&)#!()(''*%*&$'$#&#$#***%+#'%()!$)**$$!*%#+
@r9213
CCCTCGTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCGAACATGCCGC
+
==CE>?/A>!0>44/<F%E7@H==8@C$-.2H7B&)"5#H2&5,&6+FF3#'*::.!
@r9214
TANTATTTTTAACCCGTCACCTCAATNTTCAGACATTACCCTGCNGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATT
+
;H5(C$4F!)):D>2?(F1<6??$9FG>763,*3!,ADB'$#;3E+9$:(%GE>!A'FG+$4A7<,.@'#;0B83<E4<7<&3
@r9215
CCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAANCAGGCTCTGCGGGCCCGGCGTCCTCTGT
+
=05!%#=(,H%CC&#2-$*/=-E9.HA<C!9BA;BF3'25B/E,%5-$+>2)##!8#:+EH(>1D'E>+8?'<D;F<.G*85>C;66E4=#7&0;24G&B1&*.$D&A:.$)%6#$6%++-%
@r9216
AATTGATCTGCATCAACTTAACGTAAAAACAANTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCAT
+
3!7";8#,:>>69#589(;')F!EB?-A*3.($%5CCC1(F9)HA!37)7#-D5H959=-G?&9<??&.2&G2/=>)/
@r9217
TCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGANTACCGGCGCGAGGATGATGCGGGCTTGTGGAGTTCCGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGGCCGGCTTTACC
+
$#%(+(+!"#)&)("&(!)'*"*)+++##)$(##(*"%&'(&!$&(+*&$(!""*!$&$**!#(#&($)&'#"(($+)*+"#*"+*#+*+%''(&%""#"#!$+#*'"$"$+$%#$"#*#''++((%!"'!!'!*#$("%'("%#")#
@r9218
ACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGGGTTGTCGAGAAAGAG
+
(&$+''*)+'(!*'!""#)+(!+%'+*))"')&$(&"'#"&!&$$!"$%&!'!(""+'%'
@r9219
AGACCAAACCAAACCAATCGTAGTAACCATTNAGGAACGCAACCGCAGCTTAGACCAAAANAGGAAGCTATG
+
2/+8FG"*.228>/)D:@(A5C62#'$G6B7'#%:9E5*B:1/>G3+$9!F",7CH>$/,>?)+03E#"((<
@r9220
AAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACAC
+
<2@'=59<%3A6@BC/31.G2F8>5%?3<;'58;DB6,*G*5>(,%'<?D2<(3
@r9221
NCTGAGTGACTCGCTGGTCTNGTTAAACGTCAGCCCTGCCGCGTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCC
+
$1#.#3)<A4"%.$)=9H,-,*0&7?:-8B@AB/0BGCA0$=:CA"(47E&,=1C-7E"C?/H*6'&#3,,<$,-B*=F+"'7DH*9
@r9222
CAACCACTAAACCCACAGTACCCAATGATCCCATGCAATG
+
H6.6*,)B&4=@<<@A/3.F82AH)5"#C@$8"F#C)8@0
@r9223
GGCGTTATAAGCATTTAANGCATTGATGCCATTAAATAAAGCACCA
+
D';BE?F7'6'?/B8:H&0E.AD!C=G*A!@G!D=40DG8)>,*1+
@r9224
GCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGNCAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCG
+
C?:52'1+//#*?+F??/:9+&16?H<D;)E7=#@%&%$;?&BF5%"+;(-9G")>HG6G-2&7:(?:-34F-.GF$.-!&H*%7$+:%&!)-'1!%$1>,1<&&E?HEDE#9AG@C9A&%G'E;;>&44;7C+?-
@r9225
CGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGGATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCNAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTNCCCGGCAGCACAA
+
,!=.9-6C#,1HE;,!*>*<A-).G-:-?='.'F+<:056?7E"=HC>,D4."",:"--(2D8@1$&A5'%;C#3<HH"'-!,;"C/7<-:HB9:G2<>9"F.@>?E>$6=BH)"."(01-;96&?8<=".<.3@,C*(?G#8"3"%&$:@5?=8&?9#D3*.0;08'$0A+?!EE%4(2(><1#AE*($?*2)C3,?;(?=".D#%";632"
@r9226
GTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCA
+
$6,*B=AE.+8!2>$43B9H+4.4$"$B75".%:3$GC"?:;9:+?<='$-'*
@r9227
CACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCANCCCCCGTGCTCTTCCAGAATCGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAANCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGANAATAGCC
+
6-,2!-B9,E/,3E3=!06;<EHD!<5$.,7/9&=,43D)#.*/"@A9/>,-91)B&#-.C(&A55(C8>0%+5EA:626-@HH/-,-';2,GE7::A9*5F*'(GE+%/*'(&.;@%E9*D)#3*"*8G<")&%"-*:'!5(+>%3&0382%D92:09C-77D4*/BF>-0!EC&(2=.58+*),>0,?7;)918/G5>%C>4GG:?9D$
@r9228
CGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCTCCTGTTCGACAG
+
C:%4(F?13G%.G08/948><1:"4)D1+;;/(1#C84$@!8C-<2#;G>=B04
@r9229
GTGCCGGAGCGGACATTNCAAACGTCCCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGNTTTTGTAAAAACAGCCCTCCTCATATAAAAAGTNTTCGTTCACTTCCGATAAGCGTCNTAATTTTCTATCTTTCATCATATTGTAGATCCCTCTGAAAAAATCTTCCGAGTTT
+
7D<BD-!-#(+6>82796)0:H256>$A7:;GE@*&22&+<"'<F6BH3'E@5-<*'H)G,DD##$<=3)AGA2C,+6"*D3(-H#6>.,*/9H:-=(+<A7.:G#:F3:49H4+C*'!:H&-0)A.6F).#(-,-H71$0!F)?$::)<'.35F'@<9(%'<),ED'1%!/#7/C79E*(64(FBH=3,=%*69H7DE;36
@r9230
TGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGT
+
G.A,=;8=F>9<,-.+1"+F,4(G:,)B-0C<.<-"5D,7H.%0;'27=(7>08=@5)F!H6F
@r9231
GAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTG
+
>19+;00;AH)7?>1+'B,?E35A&2CB63,H*<%C8)%F0.G=DG@$-3@9:+
@r9232
TTTCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATGCCGGAAAGGCCGAATTCTCACCGGCCGGCGTGGATCCA
+
4C:G%B"):>-,=:G>A8!:-$:+H$GE;'&0@4D*!7*CB*+#6D?6"94834H?!!*??8++6D(38?;H:=7;"22DE9G8@)>(4@33F&>E,%:"-)%=1EG5F>7G80#$3+6.#+54G06G<=6!(A6-#A6058EF=G#%8G+">D1$B*7(?4,B&(.1?D%;F66!':B#""9B0(+%(*A9<6E@)0%)#"0>(?A7(1&DD#4?>&"D9H!9)8D4;-.H(8*@5<)7!'C+=G=:D&(E7#!D=B-8(&2*5+D&4EF!A086/:'1
@r9233
TGGCCGGCTTTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGAAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCNGGCAAAAGTTAAANACCTGACGCCCGGCGAACTGACCGNTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACNGGGCAGGGGCAGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATG
+
#AAF""??-;C+>"<6<*B/%&HD9/33?A@):H;6)1<=%=)6%C;&:1GC15#/'F@6F?89;2@4F0!;)/3AB329G7H%)?7&66/!9%E$$8$"4D?;%9H;D97,("?)>%87"A"601BDE<3')*?F!-5+>7C6D=H+1<0#F:?5$+C:)+@*<!?11!1H57'BE89>'*E2>)$A5:C?"G/#=FC3:.C,<)C.A$B%A,&)*E@H:92($8%-C.43-864:@?,$D)8&(B2,6(;++.9&9%38C:49B.@
@r9234
NGATGCTGAAGTGATGGCAGAGAGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTG
+
".DG:#+4"A;C7FE2$/0+)&%&0()=D1)"08E;%@';7"-;711D?84?$1%6&?(
@r9235
ANAGCNTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAG
+
*%$&<2,D2?+(A'D:E;"<;656/2%")+A/1#B'C6,G&6?8
@r9236
GTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCA
+
$H!.5D@$<,B+%C/(AED5B21/:;+<C(',(''&:.7A?9D'B9/C$!
@r9237
CGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAANTGATGAAGAATGAGGCCACCGACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGANCAGTCAACCACCAGGGAGTAATCCTTA
+
6!2D1?++.AH26F),#9>8#-1F820F7?0-D&B15CB.=$G9*H6@@G"@B<G,A;!33'*#4H&2'@G@*4C8D'5(.<,;6>$)<!G63"-B%C%>&F;$8.=,16#",6()AFC)4*();C&D;64HC)(29+-G!5BC-FFDDD$>+,)-1:*/.*4FH%B5%3:=0>=EF#.7((>$=;B=0D+5@E#378C1/3./5"F#+;AD(5B5.=-HF<A6=8(183F,-D1&#$1<4?@8:0$2)">D"F=-,D$*
@r9238
GAACNCGANGTNNCGNATGNTNNNANCANNTNAACNGNTNGCNNCNNGAGNNTTTCGNNNCTNNATNGGGTNNAANNANTNNANGTTNCNGCGCNANATAGNTNNNCTTCTNATGTNCNANNTNCCANTNANCAGTCTAGCANNCNGACGGNNAGGTAN
+
#!$#"!!$!"!#!"!#!"#!"$$####$""$!!#!!!$$!""!""#"!$##!$#"!!"!!$!!#$#!"#$$$!$#!$#"$!"!!$"#"!##$!$!!#$"$!!$$$!##$"#$$#$"!$#"!$$###$!"$#"$"#!#######$$#$$!##""$!#!"$
@r9239
NANGCCACCGCNTCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGC
+
"($*))+%(#'$"+*)!#"!(")!%)(''%'(#'+%&()&')&*"+)#!%&#$
@r9240
NNGNAGATTACGAATTATTACATGCCTTAGCTATAATNTATGGCAGATTNTATAACTGCTG
+
'"&$+%&"!(!+&('(*)))!)*!+'#&(#')'%((&(&*+%$+%*)"#(!!%"#****('
@r9241
ANCACGCTCNGACAGATTCCCCTCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATG
+
""(()#"%'"("&)'#**%'*"!%#&+(&($!!+%)(""!'%(#'*'#*%(%!(#"&*$"')(%##$+)(+&++$%!)!'$(#)#"&!'")!'!"###(&#"'&#
@r9242
ATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATAC
+
:<5*D.-<%1%2&.EE<E<5/0'12,226-&F*7E/D79/@B!@44A..(.38@92%.2&;+GA=!,<=&#@8!;$>C26&7)
@r9243
GCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATG
+
!83E(.1"&2DH637-?!2;9*=6A5"#*D?4#&"+6+,B1D1&(%B.C)D:2@(>-0)=A?@A#0!'C.&@F=0)<9CH:#@E4;F'/DF?E74:D7$=H"EH##2"D
@r9244
AACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATCTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACNTTACAAACGTCC
+
GHA>%*@-;$*@3/$.3B(?F:$-:?174:/%)":0C5,GA7/?;6EG?32CG1!;$?31/G5:&37-74=/'593"44:@3;%'@!8C)<C)408+)9!8+'=,="F+0E3,4(.6FF(<(6!0?+'2A+?5A/2)3<HBBD07').5)#2!6;#H
@r9245
CTGAATAAACGCGCCGNGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCG
+
-#*?;!A)'C#(B6,5*>"!,5E*4,56F;H.)-%E1E.#541#=356HC.,-%?H&C!G!:50B'9/+;?80$G9DH:(A,%;0'(D-7C72C*#<-@B9/@(1%*;#,#$797.+1/><A9'/,0,7!##903/HE'CCB2;9D+$7$-@-:0A4>'4EF>%C)!77F1+-!</9#16H@G=:='B38G3#CGH*:>-@&7@-97:-0#DC>5DF@$08B1=E
@r9246
TTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCCAGGACAGAAACGGCAATACACACATTACGC
+
7<#FA:!(C185(;$'!$#<9-894=$)#17<,57'(("*46307!=E#3HD$<2@58.C2$+E:$!(G>E;G5<#<!7(7:BD?6C%'@+,%>D$+6"D3/1""2C=*7CD
@r9247
ACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGG
+
D@AFC;*:"&0/B?3@E"6.+H(/""7.?!71-$2./$=0?HA<:71'AE63,4G;;;F(
@r9248
AATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCNGGTCTCCAGC
+
FH73-8@!!4$.?-GE7?)$?,)0=B2)92))8-3C4<00G372,-@B0=6H("7?5CH-.1;D.<-
@r9249
ATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTNGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCTCGACGTCTTAGCCACCGGATATCCCACAGGTGAGC
+
126:-)'13$@G?0)GG(>'."C!.%-G*.??E(@#"F&(&"8,@"C@->,:)/5!(*0BA":*B7@",<)7<;,=9"0-9+"7BA-#83:1D$(8,B#?&/??D(.%'G/,=,A$H??#)9+"-8!;&D2
@r9250
CAANANNCANAGNAACACGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAANAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTNGTTCATTCG
+
$"#$!(%"$)&$%'$)*%++*)*"()&"(&"&"#%!$+&+$!&%*++'+'++(!(#(%'"&*%&)#"$+$"#+))(+(**"*%*)+&''&&)$*!(*$")'%"#+$(+***(%%'&)!*&)#(&$'%!*%%!#&*+!
@r9251
AGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGNCCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGC
+
&G(@2(;9,>?1*0?&@E*+30$.GF</:%=/6.)7':+0:)E14CF$>@@06:D'7:>.%/"5=2.,3&/@@>1'#$:*!G0F3!5',''3#<!(*)E=,A6CC+CGD%@*:=B!54/2#9C!!:''1:=/+?6G+*"#/7*EF4&'
@r9252
NCGCCACTTTTATTGGCTATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAAT
+
$=@779"'@4E#'=G</G#5'5;6A/%'8D89,4-2>/!A=?B18:B$17*"@"?A"AFA
@r9253
ATGCACGCCTTTAACNGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACANTACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGNGGCGCTGGGATA
+
.)-,@C81'/>!/3E,"9)#<A(HA*;;62*7#'!#>:'=9;3&0E*5A*)!/E09:/@,CBC:;68>%8>1?1-%0A<@0E0?>CG$8&$/GC$?4&+37H9F<<<G)A,D6%<G.>,AD48:20'B8.5@A91<,+6##!A:*6E+=+>F/8,//D*@EB'C4;=F*DF8!$467#A.17
@r9254
GGCAGATANCCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCAACAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTAATATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGNCNTTTCTG
+
$E.B.<"-9%:8/A+>2-))'3"*&.4++%E2$3<*5"++@-*78A?5)FH2;66@8";2?1F,3+#,,C:,B*;C=>1%@@((+)GE#H+C67'F#;5!>.;%C%:A$GH4&>3%DC.'">4E>->(0;<D6)5A451+$B9!!<+0#CB.G?%C)+%(=;,5B#+#)C;.)4
@r9255
AANGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTGCGTNTGCATGTGC
+
*$#)%+*+!(%"&###+$'*++'"(!%"%(+*'&#%(('&*!(!""()"(&&$&!+&&('&(%*+('*'$(!*$#'%''"!*#(&$$#+"!&')*&
@r9256
AAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCNGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTT
+
<0?89:#4;.?&+:4/:$4.(#C%)1%F!"D-=-?'+17E#14'=%1%!$>?51+@*62,()%%H?",C6$DG$A*6-,DD62'9C.(/#8,"4')!84F'D6**0B?#G)C>-&9+.5;/,.A)>?:+,>'G>B)CB9C#C=D@33.:8(72D<9&
@r9257
NGGAATATTTGANTCAGATGATATGTCTATCAAGGCCGCCTGAGTGCGGTNTTACCGCATACCAATAACGCTTCACTCGACGCGTTTTTNGTTATGTNNAAATAAGGAGCACACCATGCAATAT
+
%,637"=B>1.''/"H$':-+D4*.4>$+?9,BG,FH$*7!+3+==E%0GFFD5:G:/25&()64.2A$;>65B:&6:@/.9F309.A@8B@?D;%G<"E08&(;@6D2H4?EC47*2*&,1H!
@r9258
CGGCNTCNGTGAGNTAATTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTAT
+
)*&!"'*!!))"*!*(&"&)%'#+''$('"((**&*)#+$+%"'*$!#%+(*)&%&+"*!")(#+%*+!%%%%+!
@r9259
ANNNTGACTNTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTAATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACCCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCNGAAA
+
&%$&(*!*!((+#)!#(!#$$$"'&*!$#)"$!%'$'*))#""$%**$#%)!!)"*!*%!*%#(''("+'&*)('$)(!&$$(#'))+$%%""+(("$++!"!%(+($(#$!%$$**$')*')!("*)'##!()*!!*&+%$#'*&'"'$)"&(+')##"!$%*%*'!)**)$%*''($#&'((*'(*)+&(%"&*#'"*!$!&#*(!!$&)+"""$)*#!#'#!"&#&'&
@r9260
CGCCGGGCTATTTTCAGATAACNGNCACGCCGCATCTTGCCGTTTATGACCAGAC
+
E;>E?F8+7(=;:"?$4#(1-F&>&5)>C@H+C"4;>(4<<8'!793DD!DH7/1
@r9261
NCCACTNAGCCGCACGACTCCGNTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAA
+
!"()&%"++((#$$%(!*+'"$+(##&!)(!""*#))((($'%%#&+*%+$**&%$#'&"%)%))$')"(*'("#"*"""'$*&(+#%$(
@r9262
GAGGGATGTTTTATCCCTAANCGTCGTTTTAGGGGATTTTCCCTCGTTTGAGGGATGCACCATTC
+
0;?-9;=>*C#BG7-,HG7;:1,D'F&70/0'"@H3H94'G60-CH5(02$")<00<B##!CB@6
@r9263
TTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGCCATCGGCATTG
+
13:@8A5=DC:&&--E8?"4D@/1="%1.)404$0H'03DE!F>%<6&*%%>0.'>C5?GG;4"82G#
@r9264
TCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAG
+
9<E88&@$BE/0,G2=-#6<B&A0BC@CG/830E9="AEG79,%B<;C">4A=8"GA>DH#>%("#&4,(83%9.:7D+%.<2;
@r9265
NTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGANCATCAGCAGGTAATCTG
+
#4HG52"=&E'3F55F%+"+3:;!%>3*4?<::1/.'(-$"0;%06>0#'<'88C(C
@r9266
GCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTNTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACNGACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAAC
+
0!;!002%?;A'/8+*$/C%=1E)+,+(3;H1D=%G927#"F+B1#@&0H:@!91'(C)G0A!9D,;D7@HE5><E7#*+:/51H4*F79H,52?1C/(&!?.1>96+1,-?-A?;5#"/8=-2+!'1:69@46;?$?FA%5>3'";B'=E$9!#$<@>;4-C4$!A-GD,1-&CB>&G%@0B<>0><!7<E+7F>F"H>2?!-?!:91CD,!?A)7'GB=#H,11"9DD70:+?(9C=<5".226
@r9267
ATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGC
+
AHG('/5?@#=<HF+5?232@D!*!&(4C98*'*,=DE,)$#78#-@<>
@r9268
CGCTGGATGAACTGATACCGGGGTNGCTGAGTGAATATATCGAACAG
+
1)!.79/0;=#/8'%0!:G0>5#8::*%,!!3?/A(!6-##*H">80
@r9269
CATCCTCGGCANACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCAC
+
5H0F*,@4>6,E-,@4-%'>63-:6,,=A(6--*B7F<D(C95777,B-E$
@r9270
CTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATNCAAA
+
*7!6<,>4DE)"?/"985.;*E5$=D4+D&!=1):5;;5823B:@02GFD
@r9271
GTAATCTTNTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACNNTTTTATACCAATG
+
05E2+#2%%&"B9D(:39H,#F;:""".=3G-!6.:<+@!-;6<7.F7"$)>7D1+(&:*D/:67>(4D*?!!@58=ACF,@F1)@@E=&6,A3/959082E10?E6.0D5C)%B
@r9272
TGCCCGCGCANACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGNGTNTTTTTTNCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGG
+
;H./<)*3A4A9#=1?C:B"1B%$$"&EBB.8,&':&CA5>40*+1G)%)*#%97(<3>E>0&F:*(*%'>-?A/-2E,)(<".*$@:@+#?A/=+4?-F<!=C6G7$5G1=.$&+/)@?C)E7<#-@7/46%7
@r9273
GANTNGCCATGATTGNNCCGGTTGTACNGACACNAACTCATCAGGGTCACCAGCAGCNTCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGNTGGTCACTCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCNGGTTTTCGCTATTTAT
+
'"!&!%&*)')%&(!)!')%!$$'&)(!+%&$'#$#'%"!)*%$#+'%#!**&($(#%)*&$!!*)%$"!+*$((*$+#*+%""*'%*)"+&%#'%+)'$!#"&&+&""!)+++"#*!&(!*%"$!%!)")*''&&+%*+*"$'&++!(%"*&''!&)$*!!*&(&#*
@r9274
TACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAA
+
52/2.7*+4))F88-DH+(>)4:+(#-/6##5G';G;5.'*&.93%8D.!5;,9;=97</>?2,
@r9275
AACCTATGGGTGGAATAAACCAATGGACAGAATCACCGAT
+
8*=)BG&B*')@+E(909;$?EACED$$80+H!#&';*(7
@r9276
ANTAANNACCGNTAACANGATCNGNCCCNCNGNNNNGTAGNCCNACNANGTNNNATAGTTNNNTNNGCNNTN
+
$#"!""$##$"!$##"!"#"$#!$##!#"$!!$"$#"""#"#$!$$!"##"!!""!$#!"#"$$!!#!"#!#
@r9277
AAGGCNGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATG
+
&((&%&*+*+(+*(%&#%'!##+$)%(('$%+)!&)#%&#!""&"+)(('!$'+#++%**!&'*!"*(%*!(')#%*!&#)!*+$"#"
@r9278
TGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGA
+
?*13C2;+#'#$>=G24/>."A.A1#1)C;6C$E607@,'9$8""4'GA1.%'0<@>G2C:(8E+
@r9279
TGCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATT
+
'"#H*G/@B"!?0&>#5.0'?@17,<91H2=$4786G@+H/H/>869<7;%>.9H0E%6
@r9280
CCAATAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAA
+
;"&7$H%D>.).(=3:GH$/)@==H;#7*?5F4$H(/,?;2(;5<59H)6!(E:('+>.#(.%6B9&0&9%)0,!,C=:%H*-2-+;-HG/1H./&G%,B1+);+?@(($7>3H<?+,6*9"41)!<H).8F
@r9281
ANCNGNTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCNNTTCCTGAACTTCTTTCAGACCATCGACGNCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCT
+
)'*$"+"*&("%#%"*&&(*)'#""*)'!*!"$+!""(&*)$#$(&"%%+&)("%"*+)"%%*(*$"#%#)$&+**&'!#$"'+&)"#%!*(!&'+('!&)((+!%%()%%#(()%+*'&%!"!)+&##')$(#*!"!+()('
@r9282
CGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTNGNGTCCGCATCCTCAAGCGCGACAGCCGTGAAGCTATA
+
-2DH3#&2G%;",&)3E5=@G6*B!.0<%08(%3E#C))E1>>)4/H%$,;EA*77*D7@E"B+,C7F7#)G8(20@GAF%?0.9$>3>=(2?:G>#-?C9F7,53C8+"@38;
@r9283
ATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACNTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAA
+
G9,!36848+G3!HB(#784@728;**(>1D@H1))FB!8GF8?;EAD'EB&3=:H.)H013-8F*DHH;8@(:AE,A3B=C<#2AC();=8>4#C,%/2EE5256!812':1>.AB&F6HA,BC:.&+.,('%"A5-8>+049#;?1.!%>E.(*G)2$'=<%9E9(918C(55G3"G3<
@r9284
GACGCCGATCCGGAGCAGGAGGTGATNAGCCGCTGGCGCATTGAGCAGNGCAGCGAACTGAGCGCGGTG
+
!*)+"$*!#+#"&("'*'$(&)$#'(%'#*+#$#+*"#%#$##"()&")!*$*#&%"'$&*%(!#"'#&
@r9285
AAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACNATAATAATATGAAGGATTATTCCC
+
F30<DG;3713?&D%)76E0!H67D/201$(0<,-"C21=C?0.D=)B443#:EE9C;6"#0F
@r9286
CNNNGANNNGNNCNTCTGGTTTCNGGTTCAGGNNTTCNTNNTNANGNTCTTCGTN
+
$!!!###!#!$!#"!$#$$$$$$!""!#$"$!"!!#"#$#"$!#!####$$$##!
@r9287
ANAANANCCGCATANGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCAGGCCAGNGCACATCCTCATAACGGAACGTGCCGGACTT
+
((&'")%(*'(*!'"+'$$$'%!*+"()$+*!$'!#&%#*$"%%"(%#%#+%($$)'$$*')(&($*+&'!*$&#(+)+*$)$+!$'#&*(&&"##''%&&!&"%'"!($'%!&&&))**+%(##+*'!+*!&''#$%"(*%"$&$
@r9288
CACAAACAGATTGAAAGCNACCTGCAACGTATTGAGCGCACGNATCAGCGCACATGGTACAGCAAGCCTGGCGAAC
+
:1/8?F:>0*&17"?*8))/,(&7>'(F.&H.@.23A75+@?9"))#1>C$G<1H14!#!:E=;C@%(:1$?D><4
@r9289
TTAAGCGCGCNTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCC
+
:DH?6!;*3"-6,/"/EB%?;*C<B6+#2&6B#*B$"?5*%.=A/".G$4,)<3"<"AE4!=!4.2%*9<(),5D0.2G#93!<B6:$)D%9?%%11=8B(<#&;:9-9=DG20'@(='>#"<4!D'26<?47#?.'%G>%55
@r9290
NATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCNGGGGCATTTGACTGCGCTGACATCATCGCCCGTATGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCT
+
';+5%D#H#./346F@1%6!@C$%#?E&:&/8%<%*>=)3F="&E/;@493,$';/)E'79+D--7@DF4F"/-*"B>!GC+,CD'/+<'A+&19/*.$:/!"=8F/1<D4:7=.;&'8HF>?52G>/.;EA3?.#:24@.(ECD=H&6F9&1EF7:A'4-25(<)%HG.C69#3(=0&//(:#7&>!6(,$=:%<37D%B!<8
@r9291
CCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAG
+
342,E#/HF*H)D!!8)<DE$:22>H#9%)B@;?+E292<#9#%=8"(CE0&*C6.?E%<+H7H@%0;')'-'+;36>:@+;9;".)>,=#A)BH4.:;#2'F>:46CH(;.@$F@4A/8""*(&&
@r9292
TGTTGAGCTTGGAGCTTTGTTTNTCTGCGGGTTATTGCTTCTTTCCAGCATAA
+
>G04./%'#&-G@,;:3)FC5>B6A70#53=C6+E/C9843!BF?;(?F",B<
@r9293
ATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACNGTGAA
+
$#)+&'!$!##'')%)#((+)'((*!")'**!+%)*%"$*&%#+$$++$)#(')"''"$&$)&
@r9294
GNNNNANGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAA
+
'%"%'(++$'+!($'%+*#"&$*'"")(&#%%(+*$$#)%!'''+%""%#!'"#+%"$+&%+("''&'&*'+('&'
@r9295
GAATCAGCCGGTAAAGATTCCCCACGCCAATCCGGATGGTTGCCTCCTTCNTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGNCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTACAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCNCCAACAGCCCCGCCAATGGCGCTGCCGATACTCCAGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGCCAGCATCGCCGCCATNTTCTGTGCAANACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAGGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGA
+
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
@r9296
TTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAG
+
/&?36)G?#&#&1D--;E;BFB;39:FF@9>>;6C$GBHD6,?=2;D8C*7'2G3/88!'(69+"BC+FED9GE!/8,<++%1'!E1%.2&'806!$"=?A?B%')):B(=6E-G)!D
@r9297
NTGGATGGCAGGAAAAAAATATTNTGGGACAGCAAAAAGCGACGC
+
+D$2-4;.*A:@#!;%;E9)'&93F/0*F&2"!A-=>B.*G,0!7
@r9298
NTGCGAACATTAAGCGACTTACTCGATGNACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAACAGGTTCCAAAATCCTGCATGTGGAAAGTCNTACGGTCAAGAGAAGCAATAAATATTACCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTG
+
%'!+*&"+($+$'%*)$'&#$%#+*&'*!($%#$)##*%*"&#+!!&*#''#)&'!$$)*('#$(&#*%))"!%"+)+$%"")+"'*"$)&#(#"'"%$&*)"(""'&!&*#*%"+'*&&((&'&*%''!(#)*!*#%+'**'+%"&+++!&'#("'(&#''$+%'$&*$$#!)"&)!$!#!!'&$'*!(&&(!'(&$'*%%&"#&+
@r9299
NTGGCTTAAAAAGCGTGCTGCTGAACAGTACGCNGGTNCTGGACACT
+
"=E;=GC;3**9A=6):H2A@8F*>D1FB$A484$H7H*4=E8#B:%
@r9300
GTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCNTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTAGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTC
+
>B5//(3!DF;1587)38<E8"F9:E+D(.*A&+0#&,-.34A+@(H4@95)"%5G@C.;30!!;0'$F<(A&@(;9,%$0+6H;/-93193C!<.97F9'2!=H*;2@?9+9&-E8*#&4D,(8/968*6BDB7&"./9<@"%:>=9258;A.G&=8,11&0='G<"?8E!/6F*-??&)?#0/B=F1C+80!A134)654!A1&+H39*"H;5%=&;/'6F
@r9301
GATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTT
+
FH52$0#7H>>9.FC@,!-*>4GH"$14)**F>C'<8(/6;!0/4:C>&B07'/$
@r9302
GTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGC
+
.>;3/82<%"*-8)1.:&.&'A@>2-()A,=D=E++&A;B)6>3#&D#H$#;.-8A756E,-'%3D%"FC"/2'B536E?:*7
@r9303
CACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGNCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCA
+
1CD%9?HA58G%/B'F)719$>!3G/5G2,C&3>.)1H3A*14'=D!9''$7CF&BE!6E(49*=E-(0)#$'G$-;)=9
@r9304
ACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCT
+
1D9('HDFA&&D@)4.3"8E$H#H'19D9-+90#B1"1$2(D='G65(.335(#4>28)0E)-E&B$)3<=F2!,0-8)E4%)29%,D4@49@3/<18,/%G'63G/-0C08!!!C
@r9305
CAGCATGTGCCGGAAAAAGAGGNCATCGTGGATAACGGGGCGCACTTNGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGC
+
DC9#2AC3/69<-+/$&!.=H292@"5,=/@@<-6E"$!+@?0A0FC??!87?%<<&1CDBB,F>@=$+2$2GF4,=&++D%)8$%.:EB2.+,B?G4.C
@r9306
TGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAA
+
3C7'5@@)20(=0)$9.=(DDGG@=><E2D<>F@%;E+E'*2A"6!7>=<F<F<
@r9307
NCCGCNCATCNCCTNGANGNTGGTNNNANTNGNTCNACAAANNAGACCCGGNGNNCGTNGTGNNNANATACNGCGGCNNNNNNNANCTNCNANNNGCNACNNTGNNGGGGNANGCCATGANNTNCANNNACNCGNNNTANGNNCNCTGACGTNCAANGNGCANTTNN
+
#"$$!!!"##!$#$#"$"$!$##$##"##$!$$""!$$$$$####!"!$$$$$!###""$"#$#!$"!##""#!!""!!#!$"$#$#"##!#!!"#""""!!###$#""#$#$##!!!$#"!#$!#!!""$!""$#!#$!""##$#$$$#!#""$""!"$$#"$""$
@r9308
GATCAANNNCGGAGCATTCATCCTCGGCAAACTCTTTCCATGCCGCT
+
$!$(%'!"%$#(*)#&$+'!%'(%'$&'&"+)*$+!!$+(""#+!#(
@r9309
GNAGNCGACTNNNGANAAGNCCTGNCCCAGCACCTGTTTGAATCGCTATGCATCG
+
(##'"'&&)%"!$('%&&+%+&!(!(**#("$&"(##'#""!#")""*!+!%$"$
@r9310
TCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACG
+
>:B6!3&:7(;6<"*;26:7H#*)F'6E779+>'6C433-+"6#%C5?)-;A)@-,<6BDC4*$+>-AD(/2#8,<(4+A'E'/38H$>='D@#=.+EBB>')0,>"BA%$+B-/$H8+
@r9311
AANGTTGCGAGCACTTGCAGTACCCTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCT
+
07)-.FDH80/A#B+;,D'68&/*EHF@/1+#2D(@!9%!!CB#2%8F#,+2*.EB)E29/%/&6EA9(=,B*,HGH1%2+):)0"3DG)G@'0?3.$B)G@@"$D49<>-5(),7/4BE.5F75=5
@r9312
ATCAATGTTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTCGTTGGCA
+
;(522!8H61#/5?D>+72%(E;7;C%",H"E0=0A-&'F?1$G6%5BH-?6*#
@r9313
NATCCGNNGCAANCGCCGTGATAACCGACATATTNGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATNAAATCCTGCAGGTCCCCNGCGTCGCTGTGT
+
!&(&)*$%)*&)%**+$*()+'+)!*%%#'#$(%('!+*'(*+#'%"&$%("%$$(#'%+"%'"+(!+"'&++#')#&')*&(%###"!+'%$*"*+*$(""*!)!%&**(#%"!%$+!#$((!)&%
@r9314
GGTTGGCAAACTTGAGTGGTTTCACTNCTGGCGTATGACCAAA
+
+)'69.)D24D@+%$)-)7->*?8:%3<;-,FF0/'";)."AB
@r9315
GCCGNTATGCTGGTATNGNNCNCCCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTGTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTC
+
)(')%*%')$!#&$)!'%"$'(!"+)*%%&$!'!%%*!)'++*%)*(""*($!$%")#%'"+!$+$)''*$(%#!*"")#+!!$%#!+**#"*$&#&%$&'&!($*#+)(!+#")")!&&+!%&&%"#*$)'+'$!''
@r9316
CCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGTATAATTAAAACGAT
+
$%+$"$*+)"!)$&&$"&*"*$&"$')&))++#%*&$(##*$(&+'&'#'
@r9317
ACNACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAANTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACNCGCACGCCCTGTCAGGCANAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCC
+
>D1??66.=<&$6"+@H37*0.C:,.B+%-<8,B37.920"?-5A46:"92:F5>,1C(401##-*&8GC1)3/*14B#<0F!5H*0(H-9)"7>9D2!;6<7H<0=)$$5-3E>:"FA"?"!;6A,C$C;>E>>6'-7(9)B*4*6E++GFE9/B326+4&3!A6666A6,C#68$6?%0<459<#5H/(7/#7'=--:805CHD'-FG0)<(+;9-!/241F356*&,B&*!3
@r9318
TTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGNTCGCTAATACGCTAAAAGATTACGAATTATTACATGC
+
3@3+:8'(>;6A?"EA$7.B7!?4D!'3%*FG9@'!$*'&9A,%C#12:FE/&.E/*>D7.(6+.&"/21=)8A:EAB
@r9319
ATATGGGAGANAAAGGTCAAGTTTTCGCAGGAGATGAGTTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTT
+
G&@<>,4<5)6?)H@''!#8<>(.B%?E/@?*EB7<3,0,C;"0&$2=E,60&2$71$GG-&'!C--2!+'.=&:C>";&$
@r9320
AGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCAT
+
C#C%<HG0'?'0"$1=,:E/'6D08$1+6(@1$G$#%'7$!#H9>B-C++
@r9321
ATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCANCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGNCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTGGAAGACCATCGGGGTAAAACCGTCTATGACGNGGCTTCCGGNGACGCGTAATTTATTTCTGAACTCGGTCCGTTAC
+
E:>A="7B"%E:!+E(!#25,-7(456BH9A1&;.7<5B:54CF(9=#3A>>(+8@%$'90#07*!.0=>1"7=*C1@<0#"&D<-DC/E>%C5:!@G=7??H(7$;6HG1,F3-"$6(F<>D8'3CC-/&+<CC,%G-5'36;--EG,"FE8>H:EF(B,HF:6,1'AF!-705B55AA*2D&A3$8'H/(!;;G3B0D(>6@*%H($(E67*F4>*9GE)8&.*-;%*E16'&:3C:'CDG@:<FA!.$075>6#)&(<.A&9B-#0!8+(%,D).!:/A=@6&?*(+A"A//9.E;/+>(&':##HF4&/F%E8"3(!7;688-#1=(<3-6DB(<<H.6)@-=#4%0C#@?<?34'A)1E/502:<E&G96#=@0/)%(!7H2A#D84'7),@G8#:#=(1H>B%>E#=1#A((8.5!6/*+08*8H'&<$->,%70,1
@r9322
NCCGTNTCCACCANNACCGGGGTGCTGNTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACGGNTTTTCCTGTGCCGTCTTTCAGGACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGC
+
"%#)*"*$#*%'("(%')&())+$)"++&&*+))$$%#(+!%+#&&!""$"%'&%$!")"*"#&&)#!*%!+("'**&&(%$))('"$%$$**#&(&#&'#)'+)+('!&+)#+(!&'!*($)!&)'%&(&!"!%))!%$#(!("+%'%!"+"#)"(&
@r9323
AGATTAGCGTAAGGGTCACCGCTCCCCTTNTAAACCNACAGGGTGGTCCCGGCA
+
+(6-A;'>)G5B+BG9)>?H:D+1//BG;+9H=;F(3D%749/H6A$+C0?DEG
@r9324
TGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCG
+
/=?251FF@"'B,;<-$<<7CG?9;GA$,0&5E)BF!!,'79/@!B)3'@>:'9H6>-A15,)0?=H,!/)9&1-$9,+&BH*'F!=B5'$:DA?.$CC!/28C4B7BG";1.:+7."4-&'5E*7@D4+&$8E%@-G9@'0B*9::+%C%F9"57B,B(G0:03$;$D+%'7#*#C#4?/6H"<<C36*?>.?D6?"H5>$1CBA
@r9325
TGNNNCANGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTG
+
'&(&!%(++&+#'&)!)!)#%$!%'*+$(+*%")*#'("'%")%%'*#*&$*$*+(*$&%#"#!
@r9326
GCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCCTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCG
+
)F6$H96<=2,9#;G6DGDA9E5C7G7@>H@;A:>7<;3=6$9897%+2.C!&FG:1,(8$@'/3"=6.3HG,D10:#G0(HF*4.>'H&5)9:/:H%+4$+@#0&2B4";9*12A4-*1#(9$F9./%D8B
@r9327
ATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAA
+
)GC)92F:(%C?E*("#):$CA(/*/>;6@@49@C@7>(B@*GG$0-"C=>E#38.FC!4E(CH(?55E@H<GC8)<<).!DEF'EG(#)3+?+-9H>#"?D8&+$9D9,:(&5+.:G&(*9)/G?"F
@r9328
GTTTGTGGCGCGCCGGTAGTNATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAG
+
!'!!"!($'+')#)%)*$+""+"*"*$*#+"&*!$+#")'"!#""&$"'((*#&%%%&$(((")*&($'%'*!))"$)#')!'(!)#%$&$(#+#+&$!'%&%#%#!"*)!*#$*!$#&$++'$)#*)'%!$*)%!%&+++*((*%!%'$#"($&())!
@r9329
GCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGC
+
!E#*C$B!8!2':(+(&/+F2C+&%:0))&A:>7A1/?F1$2A4!@HGH"-59;*H()@8C2%D"3!>!G7:"-;B=:"=?
@r9330
GGCATTGCGCCTGCCCGCATATTATCGTGAGGATGCGTCATCGCCATTNC
+
*"#,H94D0.9)'A3GA&B7BBC>EE6HF'A$9=#68,!=*D"%A8>4C.
@r9331
GAACGCGGGATGTCGGTGGCCTCATTCTTCATCACTTTTAANTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCC
+
B29!">&6@42"@9=9'#4GE?;6A0C:%-)A'1'D:/$@E&ED'.>*.%.#3./%:8G*05D!-@,=HB0<:#&</
@r9332
GGCGTGGCTTCTGGTGCCTGGGCGGNAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCNGCATTGC
+
5!?#<03@19=#HE!D<AE@$BB:)!#C'A8333?4B.11F/+&7.E?921EAE#*:'6&*FD0B!?!+0G)H%?0#&F8HD2F;F&+?5&111$@"%5'5;)@,)EB&0@,52$;"57D6,'CH$C%6<1:2$$=FGHG%E&!HE/%"=:7!8/G5&>!!B3D352B$D:*'!5?"6@GFC5096444!A>&C/?E6;>1H;H*5-((*D&G8,55F"!!/%-7FB':6@-CF7-!?$?@@:H6E6$2#%@=6FB6H#?A0*,,7E'5>FF
@r9333
NTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTNGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGA
+
*/.@"1='D6>1FAC67:&D6A.!;<4@GD"34:-);8@15F90')#$-%);'=.(B.5(?.$/6>&,6*/HG,@;?5@:!;1+8F"1<?=-98B5BFA$BH35-,@8(5G'?C:$2>C)=79HA8.&G4#8G+&G$CH&?1'@#!7/%=="/%4'7-8)'?-2,3<(&.5!@F-*'">;6:&/#
@r9334
ACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTC
+
#1G=,AC>7;!(2+60=7DD;3(?<7H.D69H8<!"<$/;+A8
@r9335
ACCGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCT
+
82B/$;5C3!(%E.)83;:*6&2C.&0$?F08@1;)?"8?E.G4F+3"ADF'$CD+"%2/>>'<CHDA'<E,=83;D+$4))"B/'+@)<393"1F2'E1##E*C#69",FGG/""G&.>:!?H&D01%!60%<;8:1>$E-6?
@r9336
CATGACNTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTT
+
E&!A;*#(!%A1,$"(!G;H?>!E%>'+3C@%6.-&3@%E00:*"#D)829.'27A3>=-(5&'C!+8<=.F-41
@r9337
ATATGANAGAGTTTAANGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTN
+
%&%'*"#"&')#*)&""$+)%"+!+"(#+#+"'#(&"(!"(&(+'%%!&("*"')$)"(!)!!*+(#*%%$'++%!'!'(#%""%!)#*'!#!$
@r9338
TGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATGAATGTGCATCGATTATCAGCTATTGGCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAGAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCT
+
016%98@'14#9A'3+2D25=?.1A7G+:%@6/63HA98'7<!A;"FE(=*%9+"3-+'1C-*$'(HE!/)!3HG;(8B<%'.F!.D>*B:D5%25$D=H>$?(C22G)GA@H.G>D?$2$9;")GGG./.88=<F4D*7!.1#B-$)'47/<6:4$#-EDH*A4&7386**:@04-*&G?#,1,!:!:D&H-C(7+)F/025=83H(F>9*GFA?;F#+4>>)D8,2*D@!+8H)?7C$)??>((><+/6A3H@362+'$.!A>$-&>E2*:G-!(,
@r9339
TGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTT
+
)+#%&'+)!(+!'!)'(#&%*!&)$%%(('"%'()#""&'!%"$*"*)+&
@r9340
GTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGANCAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACANCAAAAATACTCAANTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTNATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATA
+
7.D,9D'2F?$#4DB/569)$<#+C-$@9:.7($#'D!C#4G2!;!E)#D8#<>"###%%$*30G.'@@>:%!ACD?0"HA#?30,6D-ADF8H'55DF*)4:/263"%C22<($<?2=0:>9;!,<-#09=!E93'G=>:-(D'A.C(/?-!0A*CE67E5*>7&<@E8=319(76<&7C+:1H(6;=)C%*7(C42;#E+"A=)/@'.:==CBHE/:-6"0@)!-(6G$1;CB+*?*<E<9@F3
@r9341
GACCGACGTTGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTG
+
$$$'&"#'&+%)&()*"!"'!#'&+'()#!#"$#*(""%%*#%$#$%(+%&*'&++#*%'!"++
@r9342
AGAGNNNNNACAAANNNNCNGNGTTNNNGTNNGNNGNCNGTNNAANGNNNGNNNCTTNGTTACTGNNNATTNNGAANNCNNNCNCTNNNAATACNGCGATTCNNNATNNGNTTGGNGCNAACGANNNAANNNCGGCNNNNNCNAANGTGGNTNNNTNNCNANNTGCCTTNCNNCNNNNNNANNGNNNNNTNCNAGNGNGACCNNAANTCTGCCNTNNNANNCNTNNTTTTNGCANNNTNAGGANNTCNNC
+
"##""!!$!#!"#$!#"!!!##$$!""!$##$$$"$!#"$#$""#!"##$#!!!$"!!$$""#$#!!""#""##!!!$!#!"#"#!#!""!$!$!#!#!#!#"!"#$!"#!!#!$!##"!!$!#"$#"!$"$$!#$!""""!!##$"$"#"!#"##!#"""!!$$"$#"!##!""""#!"$#!#"#!!"#!$$!##"###$$"$"#"#$"!!###""!#""#!!$!!""$"#$$!##"!"$#$!"#$#!"
@r9343
NATGATTGATCGTGGTGATATCCGTCNGGCAATCGANCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAANAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCT
+
'+)+!)(((#(*(!%%##'"+&*($%'+)!#+))$'&'%")*#)#*$)&'%&'&&*$!*+%&$!+##()$%+#$&"(%$%#&!(!&)+'')&)*)(!'')(*'$$)$#&*"+++!(*"%+(!')#+(!)('#)(&"*!(!&(+*&#$+)'+!)(%)"!*$!!$%+&#!##+!*)"'%%&*%%&!$*("#))#)"')
@r9344
GGAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATAGCGATTTTGTTAAGCAACGCACT
+
'(-*&'6)AEF3/:*$5:>EE%D5367'97H7-G!D%6;A+G1@=#H,1."B52:7B+75D&6>'A.!2+>&,1(D;6<#(%$F;D>>#&<8B9BF$3,=#38/3$3C'D@">8.3-&<);
@r9345
CTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATT
+
F"-9@A(=99D:!?-9D0.B#C:-':-?3C'%5B(4F'F,&26=
@r9346
NTTTGCCCCCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCT
+
!5A1+6;#A=8$.?4=.&:A,2(0,!..>-FG%?3D%D1E"20:4A*20F-.>.'5+D><(0*,H($F/:-<&8A&=B
@r9347
GATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAA
+
H192;HH%HE&#C"H'()4&$!H-!+7(3=$/<#8.C7%0++**H=;+8*?:=))8C?3(1)<&<B!=?*)>FG<<9DF"'7E7%/5>%:)=1G<B+(!8%/.45?*6&38.=(<99?>AGHHGD=(:**4(!7@EH
@r9348
TAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTT
+
F4**$>F/(BB>+9;D2&%$,&?E3,@$9!C7?,',=4/+4=G%-@G1$94&F*(
@r9349
GCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGC
+
(H0G*0/"6#2A?0H"#4B09)$6)!$*-%14"H4H"#<@#=C/$$A6,';E1AB2714@+)0(E;:;0!./,@-/-31H727(>6"EA946C&!F?G%,
@r9350
GTAATGAACCTCTGGAGAGAACCATGGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGACTCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATG
+
7'.+C:"FH7D2$.'/#.<E:1&4C.1CCA(.173E'/C:!7@?"-&:@$1221<C<)0F4)E)>763F/7C%,2()H!E1#)*4>#E/A&G-"28$#AF'H<1'BCG*-$3"#0,0(D?<6C;?G1F"51@0(=+-4G7BA$?8DH,83<+79G@&=HE"D,
@r9351
GTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGT
+
0+C<#/D6E:,$4<4-$=E5030.75%#=B;28(&G-#=%2D9-63%)(
@r9352
GAGTTCAGCCATGAACGCTTATTACTTTCAGGATCGTCTTGAGG
+
?,296.&<.)$+4E54GG3!#BDBD6>B-C@+F&$7#7?D;$@D
@r9353
TGNTCATNANNCNNNNTCGTTGCGGCCTCGTTCGCNGCCTGCAATGCCCC
+
&&%#'%&$$!!%#"!"+&$(&!#+'')'#)%"%)$%('"'+%))")($%+
@r9354
TGCGAGTATNCGTNCCATTCAGAACTGGCAGGAACNGGGAATGCCCGTTCTGCGAGGCGGTGGCNNGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGACGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGNCTTACGCGTGCGCAGGCCNACGCACAGGAACTGAAGAATGCCAGAGACTCCGCAGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCNGCGGCGTTTTCCGGAACTGGAAAACCGACATGTT
+
#:?!2(/+!+4%478D@,D5@3+E0<6?,5<F70HCE1-@9)4!=-/#@GC7+-68<(<+D3C.=+<)/80;"!%>+;.AB'!9E)/+A+'0H&+:2,E,4F1B%(>>2G1,C90=>84A+;)H';A14!#/,1?62:35F6<8(A)>=&?(8+@G#*$-D1>C(71H0;B',2%(?B(7?3'!7/7.<F6+;!.&/-2*%=D'*-*B)!B&#$B?=@;G-D")7!A/C)78$EHB,E=)><3;7)*>4*)@9#,:#@*D!?%,>3EC18;:H7ACD3+.B4?F)=6@530<-H*>7<$>@2%<G21-%?,3=A90818B89+8!,)B/H=(=<&):*9B*F1H9*?3+<449#;!E22!"4#.82#>?83A367,#!FC7'E>0$4$@A#,-7!+#8/0+C&G&1
@r9355
NACCGNCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGG
+
%'H/!33&<&B#4;DFH>+===&%43.'AH%0661*65E<9+8E+805$(02';H$FDH3*,<B(
@r9356
TAGNAGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCNGTGAAGACGGAAACCAGTTTCTTGNTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGC
+
#%(&+)$'%(%!!&%&'#%+&+%#"#('&&$!%)""#)*'+('#!*(%+*((&&%'#(+''!'("+(&"$!(+'**$"%'%#'&"%*!$$$'%$#'#"(#%'*"+)#($()!***)'$*&)
@r9357
AGCNANTNNCANACCANCNCTTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCANAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCANTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCG
+
'"%!(&(!*##'%&)&#"')+*+")("!"""('%!($!''#%!#**&*+)(!))'"(%!(+#'*"!$"%+#&"))+($#'%)%!!)!+&$"++!(')%%#'((&(*$)()+$%'+)()#))!*''%(()%*"")"%+'')#&!&)#(#%'"+&"*%(##$###)%(&#%))&*&'(")*"$%("#'(*(#!'**%%$"'+(""($"')+#+(+#*($"#+"!$"!(*&#'"+*"$"($#'+(#('+&%)*+%+$+(
@r9358
CTGCGTCGTGGAGACACGCTGANCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCCCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTC
+
AF#@E9A"C98%6'=:F89(9C>H&2&<18>0.F@"9AH"!!G15!4FA!;>5-!A#'B/8&B#//BB6'8$#F.6$E3H"H0<!?168/,057D,A+9'F1+C<#1=A*7:65H2:1+>B-'A
@r9359
GTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAANCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCA
+
3/0#:GB4?=14<F).=9-H*3-1HE,910H1@$.:D@7F,5+.<#9-0G!/.B;8!0E3DH0#'!*H0B,..=D)5F8'#8B2GH3F.)16&8-=F!@3!4*G05.1(&+!"?*+;
@r9360
ANTCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGG
+
#)(8F87?HD1#/HF6"-:A0C!A3%H2!68""16A!9H-6
@r9361
TTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGNAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAG
+
=0+40350:/*(147$B1?(6B#;H;#)G3.:9C??BB?@$AA<:9)2H&(0!8C)2FE@7'!47$C3#:?+&E';:90
@r9362
TNTGATTATTNTTTGAATCATTTCCAATTACCTGAAGTCTTTCATCTNTAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTT
+
***$&+%%!$'#)!%)&'#$%+!!+(*#''#+"&'&+$%"#''"!+(*)%()*#'$"+$'!&))+'#!#('$)"%$!&('*)%!)$+)!)'#)!#
@r9363
AACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTA
+
'?F4GF3BG.,B:<1&((*/&,%//*,/E)7@9*A"5*"<+>>!17)8,#/!FF%4F0-2%*)+;F'9<?$/0E=+A'C%',@4C/A<5F&B-7H1%<!<&C-=>.3G9@0'0%@B1G&>9F+".!DD*6
@r9364
CTNANAANGGCTTCACNANGTGCCNGGCGATGTTATTGAAATCTGCGATGATGACNATGCCGGTATCAGCACCGGTGGTNGTGTGCTGGCGGTGANCAGCCAGNCCCGGACGNT
+
(&#'#*)!%'"*#)&*&'!(*#%!+(!&$*''*)*)*%+'%)&(#$&!##!$"!))%+"*%"%&&)'"**#&!!%(!*%%(%!#'(&+&!'!&'+"(#+$'"&$'+%%'%&!+)
@r9365
TATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAA
+
&#3,HA"(EF,6#H521'4+@*46;+?%D$/.1,?70+"+H?3F<,>'D5,).)
@r9366
GATGCAATTNTGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAG
+
B1?,0FF/46-#5+@"(*E;80,H,6E9#&,?5B)&G-*B$E"+A1H(C2('/)4=("@2F8FH'>C8.-%5!
@r9367
ANTAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTANTTTNTGCATGACTNCCCTCTCCCCCAANTAAAAAGGCCTGCGAT
+
#"&%(+")#(#$&!%!'"%)##!%)'"#$$&!*(#)''+""+)'+%++!($"$)&+*%!()"!)(&%$$#()#"%*#$%)!""(+$$&*
@r9368
NAANCCNCCGTGTCGGTCAGTGGTATGACCATCACCGTGANCGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGNTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCNCGCCCTGATGAAACGGCAGGCAGAACAGGCGNAGTCAGACAGCAANCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCGGAAGACGCAGATGCCNTCCATGAATGANGCCGTTAAACAGANTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAAC
+
!(*!)(%++$'$'#%$&*+"*())%!*'*#&((**!!'""!%*)*!)(""'*"*+()"+#&"++(!+(!*(%("*!!*!#"('(!)#*+)$(&"#'&'($*+&))"+%+%($#!&&!#!*!"%*$)#$')!(($("#+(###!+$%!(('"!(!'((*%!"$*&#(#""*"'*#(((%*!)%%&%*"!%+#)!"&$"%&*""%$('%%##(+()#))#&%'+*($**!&%(+)"))*!(#'+$"&+!(!+'&#$#%(*((%"'))(!'%(+"+!&'!!&)''"&$%&!+("*%#+$'('*"$(!$(")#$%$((&#$$'%+#!"(#+("+&#"#(+*)"(%$!#&('%%*)#!&'"')%!#)'&#+!$%%"(+#)$)!)!)''(%"#!)%&&!'#('$""%*$+$$'+((+$%"&%%$$(("()"&#*#("!**('%%")"!#%*(#($*&'$%*!
@r9369
CTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACNGTAACAGCGGCAACCGGCATGACCGTNACGCCTGCCAGCACCTCGGTGGTGAAA
+
*+;&+:1@<562D9.H=F/9G"B.&)E$+''HC9+$482F"+H(B?-GCDEB,F17',".,87&;!HE,?*2F;;%E=@DCBF%<!0=1(FC?6*90)-DC)E<:4'3A1&7.;>+":A?53-,"$*>$98/=&*A.9")-:BFD%%&'?E8AB9&!(44
@r9370
NAANGTGNGNTCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAG
+
!!!%))&"!#+!%&)'+(")&$)!"!!)&&%""$+"#'')%'('*+%+"'!'&*+('**"$%%%!!*&++'
@r9371
GCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACC
+
26C*8C6ED>E%HEG,35!1;"6FF<&516#6'%%@@0)4>CE"&0H;C%F$/G;@&H?2?A01!71E0)3/3E!74H)4'+EC=,@F'=>5=-DG$4!#$*A<3A$%%H"$0@09>1@E"C2,(%??45<
@r9372
CGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTANGGATGGAAGAGAGTATGTGTTCCACGAATCAGCGGTAAAGGTTGACATAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGCATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCGCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATAC
+
/G4!'1(<BCG)::'7EB0?9>25!&.D4E9..=3!/5>"?C:$DG#=!)5/"5!GB((7565356(&89&/>D?$D"!02?C=:D5?&$&3HF?$=@?1==@"&*1?2;9&&E1D?,A)<E.94;DG+GH.!G$G>)&&)32F%<,&:<0A@#D(!A607A.A.=C81$);4-D5CE5("$/9B.E=EF:<%""%(+0;&HF&'<<*782?/4#6(;="<F)C9)=,+8%"5!80C.#.81<(&E9>F;)CE54,-+E:7$E&1!>(,;G=?.>H:8
@r9373
TTATNGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAA
+
("(*#++*"%#')(!&#+%!#*&!"!(('"+%")%$%#(*
@r9374
ACCCCCNTGNATGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTT
+
'&(#('%#!%"+&&"*#+)!"!))!$(#*&*"$+#&*$)+!"!"#'&#((&)%+%$!+#+(*%*&("*)+
@r9375
TCAGGCAGCNTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCANTGCATCGCTNGAAT
+
;%2*E//*H9$)B3@.4(+>A'C*>7<FH%+$1E';-3F166&@/8;!85$#E%#AH@$.&;',2#7-291)*+:5C;8'0%0,EA@!<95,.@6$1+:5F2,,8?$D/46F$2'?=.;2:3B2,D301/)#$'@D(/"4>0@+)="4%>$==D10<)6:@89
@r9376
GACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCACCNGTTCACCACCTGNTCAAACTCTGCGCTGAANTCAACACGCAGC
+
(+)-A+*:BBH:@5D465;3&$5A4(*$#19;F%1.B&1B?84755D1;6G-#H!B<EA$7,7@A9"'-$>1?2=D"A<!!E3,-8HF>&F"99"H6A
@r9377
TATACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAAT
+
'+)$)'$#"&"$*(!+((&$(#'#$%)#")*)%&&"")('*&
@r9378
ACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACT
+
H4,8BFGB130E-4#ADE+#3)<$B):G"9-<<0@3(/@(&BGF,%):7GA"B
@r9379
TAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAG
+
%+370";?"F3)#H*+@:86=:!?$>)-7-3?26??-7FE<.7@,3//9D<B8**5-?3
@r9380
TAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTNGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATNAGGAAATATAGTTCNACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGC
+
G0A'!5:GF<5/0G<C$=5FGF>*6BB;HHB?GFHF;(6*=@2/2?4=G='=>.!6-EG0=>9;'9:8'!#@B&616&'-"#F0>>/B!#G6&6--(6"A,#!C2>#.HD&-7+&B0@B&B=!2((*"G:=DC##0.E/7#6B@(E-G9+B:945-'F!)A2>;,>?B6>+"%?8#=85G8D3%"8?/1=+28->&D&F"1-7&:@97,:>'H"
@r9381
TCGTAGCGATCAAGCCATGAATGTAACGTGACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGT
+
B7"*&<496.!%G46<.:>EA4+>9)/=3((EEA.*')6;,-$2,H?B$F:8<=4D-8&&D5E?*F(&30#-4)62=D*2%@7',.HG:#HG&16DG3B461*1#
@r9382
GNTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGT
+
""(@!+3+=:+H-(877?7-F8:%9*9:#D*H??,0?+;#
@r9383
TAAGTCGTACACCCACAGTGCCAGTGCATCCGGTACGGATTT
+
G;43*).C2(15$"B,<<@!E%?=D.!,?/0H0*:#;#"*C=
@r9384
CTGAATTTAGCCCTNCAATCGCCAGAGAAATCTACGAGATGTATAAGCGG
+
H3?+*2+09@E?-C8D&#;8>6'C:::46=+3!9.A8E@:1#D"+A/HG?
@r9385
AATGCATATGCATAACATCGTCTTTGTTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCT
+
&:9!:*.?9':$9@"$A#1$)FD!<22.B3.0"+=;E$0HE3EF>,496/8;3>8DC*)-/"0
@r9386
TCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGNATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTNGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACA
+
*="B@.7?81?"*==)!6"C78B*<'?>E2#@F=G'(<<.'(,91,<D#7B$3E1G178F3*/$HC08(C86.,G7F?E7A6789C.&;2>A340%:A;8=?/B(26)10A+C$HE@)$C!>H:$,-3:2&63,-
@r9387
NGCGCATGGAGCNACAAAATGAATAAAGAACAATCTGCTGATGATCC
+
&*6"6;3B@8+EG-D-5CC@0<BFG%<+0>!G'B16$173&;F%&0C
@r9388
CACNCGCNGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATANCCTT
+
$$(%&('&+)+'&('!'##+(+)!)"+)()*'!$("#'(#$&*'%$)'%#+%!+$+(+#$)*#+*()&+("()%)(!($$*!&#+!
@r9389
GGCGTTATCACGGTAATGATTAACANCCCATGACANGCAGACGATNATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCNGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCNTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTAACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATNGCTGCAACGGTCGATTGNCTGACGGATATCACCACGATCAAT
+
+C'$+F>),D-?!G:4C:-D>*)D<>HEH2'3+AE,%CB*>!>6?:./(?B*(2HF1DD"2"#5@7(%D0'(19(=G2(A>928>&HC4.'(+4212GC:=!8$A3-274H2%8GFCF71>@(($2&1A<?9!F)H),/9D<#=D(/-1%7/'916@#:<<7E'#C=EF8%=%9G;)0$:0H@8?&=6)%F!$';H/,:#,:54>9)8"6=-"G>-*1F1$1#@FD76,.);3'7@8D*6AD
@r9390
GCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTANTAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAA
+
(-%%!(9>?,->&7?+(:<!3498,832/8#0+&3D/H/2B!2&4@,D)*7B?7?<F4C=,?(#?E&:1>:C->>"-D=H0/DE+*B34:46!"3!H.&<A<169F4!1D<?5@@(@*5+-+-141-
@r9391
NNTNGNCTTGNCNGNNTTNNNNNNNGNANNNNNGGNNNGTANCNNCGCGNTNGGNNGAGGN
+
!$""#!!!"$!""""#$$#!!!#"!$!#!!#"!!!"#!!""#""##"$#$$"!##$#!!!!
@r9392
ANTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCC
+
/?+EB=!=%4;F-D?9!E>+!4.D!'6=(5,E8"#7%6%12;'?0H1CE:9#5A&4+9,>*7"/-'59;:-%$>$'%2"
@r9393
NCACNNACNCCANCACCGCCGTGCAGAATGTGCCGGAAAAAGAGNCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGCTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGA
+
"&*(!"*"#'#+*+(!#&""+#"*(!*#)&#$$&'%+$")'(+$#"$*'!&$%!(%)#((%$*"&"'"!)"++%"#+%(%)$*()'+$#&%(+&&($&"#&"#*++((&!!"#%!+*"#'(#*+&('*!'!*'*$'''"*'*'(+**%'&%)+!)&!"(&)'%#))"*)(#'')!)+()"&
@r9394
NCACCGGCACGGCAGTTCCGGCTGTCGCCGNTATTGTTCGGGTTGCTGATGCGCTT
+
",>-<<,")*/*B:;9434"'!C>(@F5=BFGF%B72C7*>;7-//(G-03GCF*2
@r9395
NAGCGAAGCGTTTGATAAGCGAACCAATAGAGTCAGTACCGATGTGGCCGATAAACNCGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGAT
+
#'15>;>H512&$*<#",DE57-;C93@?&,49A;>E4+;/F+3@7;6C39.5>"F%-CA,A,!31--8#%3;1,D=E:?E.)&3/?%0%B5+;4;BC6H,()/;E".3@0">1!?H3"+B2H0/<5
@r9396
GTTNTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCNCAGTCATATG
+
.7*'@+96%'8)>*C9/@+4';>H,+<2(A:H&;94C##2-&E.8&E2"A.9
@r9397
GCTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTANCAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCT
+
"":50H'9HB;-'':8<3-7FE0"B&2###).>#H:6*D+AEF:4!A<G7!E9%@$5/2C9,.0#9<?2/='797(*"#CD::,28&?3(=G.&-<EFA567-8EC"C!5<E3
@r9398
NNGAGNANGTCATGCGGCCTCACTTCTGCTATTTCNCAGGTCTTTGAGTTTNTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATA
+
$#*!('%#')*)$)()+$*+**(%#&'$*#(+$(!"'(!(#%#$%((")+)!*'%*'*&'&"#+&"("&%!)&#)#!!+#+'$'!&"%!#"
@r9399
GATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTT
+
C,G'!$71.1@C!DG,>G-D3<"89)3*0"=5<6-$8!+88266/*&&(%023?%F$F3G&0+#&F)/#-A+65A995(9()1:!7D!/H
@r9400
TGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGNAGGTGACGCATATATTCCGC
+
?/6ED&0F29#(*%>;>8<-G=19-FEG)'0;/=#=EHH@G!F!('$*%"$:A,E3'HF.G5C'DCC!E71%#4G-//:-G8>D;@?/GH7+:5-5-<'!,7*D??,//8-,9,D1D&4&C#4.),6%21((=;83/C@.+&(E-,2(<.,D:?0@(H+B'E=
@r9401
TCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCACAATGGCACTCTGCAGCTGCGTGNTCTNCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTANAACACATTT
+
-><AC>5G9!.6.($(@!E&H:D:/+?'?@CHH<6G$!H+,0)$7(G-D,.<H$H3)B#&E"=%-DB58*A1*F5?/!2);39"0,F.,05**+GH=B#0$+13'G90F+?/2#:<>
@r9402
NAGANNTAACGNGACCCAGGNCNTNNNTAANNNNNNGCNNTCGCAGATNCNAGNTGTNNNCNTNCCTNNGNGNGNNGTTGCCNANNANGGNNAGNANNGNGTNACNNNNCNNGCTNNCNTNNNNCTNCNACNNNNCANCNNGTNNCN
+
!"!#!!#"$"!!"!$!$!!#"""$!#""#!$!""$!##!#$#!"!$"$!#!"$#$"#$$!#!"##"$$$!$$$!!!###$""#!"##$$"!"$"!!!#$#$##!!!!$"!"!""######$$$##!$#!$!"#"#$#!$#""#!"""
@r9403
ANAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACANTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGNACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACNAACCTGGTTTTTAAGGAGTGTCGCCAGCGTGCCGCGATGAAACGGGTATTGGCGGTNTATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAG
+
%#(B1:A&270F4.ECHG39CAF((5)$=$D55:B"'5#,,-<7&%"?55A>$44$%E?9!9:+/$.@*AH8H#@+10135(+%:)E;4DD5<%$$@$4?>E57;5;?C+1!?&/("(;7EE:?70!*E:*G7<310+@?22%+,B4CE>!:/-;!FA879+6$!#5A/!),51:(8(-/?&DFE!<*$2D6*49?>9@+&@/!1CDGG0F<$;+:9E;'&83A8?"5438+*"!>&*A@+&'9DE'9G+5/0"H&872A*'1':=86+B"8;:72:A!/6,1.*9%-0EH>*C!8?-</$H84%!>'/>63/#4D1-0H(.2>*6'
@r9404
CTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTNTT
+
)FHC'<!,H<!*E5H?HD9.+0=,+-C$76G>9@E?9F(%?'
@r9405
AGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGNAAAGCATCAGNTCTTTCCTACGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGAC
+
*',1-'%4!&8?/%0;C#59=/3=9><3./$FH/?/&@446>*)?%7E2B<&';>D,,0+DB@=6$)->9D&@42A.4-G#;C,H;.#B@C..-+8)/D)+E54;=3;,2)-2HF?+?;99#6933'.?47(*B0>G@"%<%<$AF
@r9406
ACGTGAATGAACGAGGCGCGNCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGC
+
2.E:0G(&;.@,9)$H;"<E<."<G+'704H2-9)5.<A,!<'$><6.03)>9(6$4*+-
@r9407
TNCGTATCGCGTCGAACTGNTTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCA
+
9,4.7G$!0=<6(>8=/"D"@H('2.'E1&%,"@!+EA3+%>!4";@2(>*3G%8984!%C?3A<-B>)H+'-1$>AE"$>57<A-9<A/$##C5E.)2)?F-6&.D1'6+F
@r9408
TNNNTNNNAATNGGTCNNNGNANNGACANTCNATGCATGCATTNCNGCNNNGGCNTNGNNNCANGNACTTTNNANNCTTTGNNNNTNNAANNANCNTNNGNNNGAATGCTGGNGNNTNC
+
!"$!$$"$$$!!!!""!!$!!$""##""#"!#"$"$$$$$!!!$#"$!#"!#""!$#"!##""!$$!"""$!"!###$!#"!$!$!""!""!"!$####$$!#!$$#$!"$"!$!"#"!
@r9409
GTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCNATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACGAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGNGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGA
+
7(%9@G5>5G0<>5#5"=HG?9+3;3/=487)(?2%*H"$$8-A+1*D2<%!92D$&?2"-061H0<281651%<;?61'E,+2E4.*H,@!,>*?D-2%DD,F'E.C-<("9!C.'E</4028GC9?B)HDGAD?A&%$<9%-,2H$)%'"H"'.<D-#&86%D)@:3,A-9+=&?28))H;@;A?'8&G!?=+!/41:F79+D?;F<EF(*'+>!8
@r9410
AGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAA
+
:?0GC@2(%2E9*13$35$AH0$6/1F+.*%D&/C(7<"74?>A
@r9411
AAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACC
+
/:G":/CE-;(79C=.%7$B/3&<C6$4<C$-;>@C0/G$H5=DF(=()755<@;5%'>FH6@:1")-+F:,740+E(3+?8);
@r9412
CCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCA
+
3;E0/"&.H&DH2$C2#*.9:)8<(B*G/G(.=,(B.$H1#BA3%
@r9413
AAGAGCACTGGCTAACCAGGCTTGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCNGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTNTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACG
+
&AAAC8C,:-0"1&"'A>7CH5;BHB=0@;0A)9FG4"F5(/B.!3+?;$,>.B"C-E',!E<G(H0CH0/0,3=:>@&"5;)%H"7@!G(5&.$@GD9=:>!-";#C,,$(+D/?".3*00GGC2&F/".%0<C>+.*B&=7A99'3'%?$=3,&F#*!D'>+=<?.0+%GE71#8;
@r9414
GNNNANNNCCCTACNNTGNNNNTTACATCNGAGTNGNTTNNTNNTGNNGNNGGGNANTCGNNNANGTGNTNGNCNNCCACNCNC
+
!#$$##$"!!$!$!$$!!"!#!#"$"$"$"$!!""#"$!#""!!#"##!$!$#$##""!$!""#$$####"#!""!!$"$#"!$
@r9415
CGGGTGGTTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGNCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAA
+
$&#$(&"#+)#$(('$)+(&)$'$)(*(#*#*(%""'*++)%%*&(&+#$*"$*$!'**'%$%*%)""!&%(*!"""$+(**"*')%!)(+#*"+&&)"('!
@r9416
AGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCG
+
.4&97)"!)D,".7-9G**><;!)7;&D):@>?-#$,C%*7'B-5'>G?=)DB<.9-<3'6FF0-0B91&00,54"<)
@r9417
TTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCAAGCCGGTTGCCGCTGTTACCGTGCNGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCT
+
@=!,$($FE!@-E<165#>8F,(;AD9<E5.8H="1)G1&'@(E-4A3)=A8'<(:=*=<A@BC.7G';H8379>4<:+8BD;>%/G9>=74G@B%!<4<*%(2F5).,6=/7))AF.>;!8$C">>$#D";8G;<%>B8%6E,F,%F+&*#4>;'D9<;8:'8@.!#+#%>C&$?#?1.,-7+)2/$CGF*?&E!45B1=$-G.0261:GF8>%7:1@B5D(+9"$F!!+(')/'#8'"#/+FF"*>*>HE!G#A@D-)990554'?)7;/9E)GB$E9#G:)E
@r9418
AATGCCCTCGTAATTAAGTGAATTTANAATATCGTCCTGTTCGGAGGGAAGAACGCGG
+
"A*=G>-=?&8<45<=*B1F(H1><!*$&33F?EH)G*!'+&A&-"1(#G;C%)%@/;
@r9419
CGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTNAGCTGAAACGACATACATTGCAAGGAGTTTATAANTGAGTATCAATGAGTTAGAGTCTGA
+
5!G7*+:A;A4#3;/$H5>,1@/FG%20.GE*!"1H$$2,9::8;$3#/<(B=)7#"$B&-G/A6?;D36E02F+C)!9C==78@C!H$=(/$7%A(7"=@1F87,E#(,0'1
@r9420
CGGCNNGGANAAAATGCCGCAGCCTGTTAACCTGACTGTTCNATATATTCACNCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCT
+
('*%&!*$#!+%'*&*!**$&&*")!%)$()'!+))!((%)")+&)'*!"%'%!"+''%!'"(*!+*)#+")++$%*)%+&"""(%!
@r9421
GCCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATC
+
&"3'*>7/(.=5=?1+H(A=@F:/@G)@(;$?)%'$6@E#BA(<37A<+?>0CH10.$E*&@**DH%E+D>A4.%+
@r9422
TGATTTCTCTGCNTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCTGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCAT
+
E/)%9+F3'357@/681,DC>%1E@D@@?0G+8"1&A09:1"05D-'00AE:)H=G=+%C0B!0'!D%4"#8=9(**53.?%$>+7,748.?G8A.?7(H-<2!79.!E=)0/@*$"D*>E7%$)F/1.-;C;1<&->2%H.0*B?D)6C*8F3!',8*=4%/77E;.(8<?"(70;$F(>/%F829+?<H2<-<(#D(//!D6='7
@r9423
TTNGCGTTTTCCCGCATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCTGGTGGAGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCTCCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGT
+
))%#"!+%)*&"'*"*&*($&"$%)%#"+'('#%$&%('&#&)*%$$*%%*&$%#)%)"&#!'*"!!(#*$(!(%$++!*)""&&$!"$)()#&%'%*)($#+)%&#+'($$'()"&)$')#&+(&*"(!''%%&(")&"&*&%%#$&(#)"'%()*##$'%*$+"%)('$'#!%%'$(''$%*!%&*%"+&)"""!"%*#+*%##!!)$+$)&!)+(''+(&#!'''"("*$"#&#&*$)&+)"**+)!*#(++)$+()!$$'%!%(($#'+$'"&'+!"+#%!&$&#'&+&"$$*)++'#(*'
@r9424
CCGNGAANTGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAA
+
%)%#'$(!+''+'(%'')!)#"('(!'(('#!(*()('**&!"!&(#"
@r9425
TNCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTNCTGATAGTCGTCACNGCGTTTTGCGCAC
+
&"%)*#+*!&+$++)$&++%'&#(%!#'%'&#((!'"$+++'&#(%!!%()'%"!$$$)(%%#&#)%+'&*))"$*+#!*"%(**)%'*+%)('&(&%$(*"#*(("!('%!(#(%$%'$*##(("+)&%$*&)+#"!%
@r9426
TTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACT
+
<G+5:)0<>3&(?4*5.HH,,?+07','2!;-5,"6G*:;+9@4;&C>&6&?D:2D3%!C":;FF*%6>4'G!19-@<C?
@r9427
GATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCNNGCTCAACAAAACTAAGGGCATAGACAATAAC
+
?@C@3862?'0E$H><*2:%BH<$>#/'G!1.GF%81*2>6!&3H<@8';(;B,&78;.!3'$7+E"317(%8F:BG>"1<CC&%A=,CG+%-//:.:=
@r9428
CNCCTGATACAGCCCCGTCGCCTCCAGATTATCCGGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGN
+
2&+-.6A77;D65!=(A=&E@6>1CD2DGBA=##A!/4E).;<=-9)66.#=!4:<0-:&A!%.A=;7D)"*@814=;5A5E'D-E9+./2/%@&E&,B+#*("5/,G9)G@B#@C4A7.%-
@r9429
GTACCAGGCAGCAATGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTNGCAAATGAGCGNTGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTATTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATNCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTT
+
E1/?',5*E-1F?#3:@!@-*>8,87$1%&.39F(;5G39$-/)@<"#A=$,41DD"D.==!';%G>0GF:)@?A6)0!'2$@$=#3.H:EH4B+5%,)C""B&+$9ED7!-6&!+@9<FB<D%DHF!8'/%1-#3'1>1.'C74?%**1?GG'"$;<'+-AE3C+FCD$;H16//=D6=>9@,%4(0%H*D(3@#H?!H.-.#?3("/D(3#H=B$9%81B:B=H>)C9D12-CB0<:;,2B/;-6EG)C5&,&;./:H2F)'-0<G&96),;H:@C6/3C5=E;+)"1)7=(=F$8B,%2E??@#3.F;7#&(1;B>#;;4F!A:<(-0BE.D'-H;DH"F,
@r9430
GCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCNATGAACTCCGGCACGATCTCGTCAAAACTCGCCA
+
B>&@E>:588:CAG&)!8/7*;-'>:89%%:3060;(5./1%,*>-0<D"63G:8A-C9=C@0="(+2:,'7.9'F)E%'H;1<F944G>
@r9431
GGGGTAAGCGCAAAATCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATNACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACANTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAANAATCAGCNC
+
D3G46FF=D";</'3!F<CEA1#,(-BF@@4.6%>)9'E!/11&,16+%3C2&0!+/B@G9*B1HGDA1"9,:+E%>%@>8!90,7$(2?"+20"7*H:.31'?)2*18@??3+;0/4,H2-,)#5>D,;A-/77:5;G;EF:.5C/B@82?.@C##8':50
@r9432
CATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGG
+
>5+4*=C3$A#:;:)-2-@.7C):+34(57)8>0?C55(%AC$+=)#!?+/64F?>,#2(GA/7,F&;2+F'$:8>=C27&=.0%C?<.7'#')1)
@r9433
CAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCCAAAACGGACAGTCAGGGCAGCCACAGTCACTCNTTGTCCGGTACAGCCGTGAGTGCCG
+
<-G<&!EGF/C9'G:8B&&6>.'?$8;>*E>;A5:)"4/-,*$;9#FE5C.31>(?A*""(CG(#!#">4&5$A,(H7;=$8+5"69&)A>=3>,A>91E6BC3$@0$G+;01/%>9?6H'!5
@r9434
AATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGC
+
94</@#1#*C?!9*!"*47><@HE'77#'4@.)B*D4?H;A6&7H9C:!2=@ED'5!.B2D:H*#G'213(EGCG./8E51G64:/GD1#/-/E5-=E8=(06C89!6&@,E1(4
@r9435
CGCTCTCCAGAGTGTGNAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAACAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAANTCGCCTTAAAGCCCCGCAGTTACTGGANTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCG
+
!B,%B-EDCE$H;:5<5+,?<+"+50%C2F/,/GF:!/F.4/5+2;8A9E0!"'7++9204=F2=>93!,/5)"";$<+*&,$2".7?/*#FCH6FB)+A<>$#C4.>?B@E(F@,5F7<";A;)79:'=#4@<E:+<%;F)5))/(!@#/-2<;E+$<"FC)%E1HDD?38*A2:H,")7CB?3BC<<)A'=*,"@94F;=+8$C#&%HA7F%=5A69&!/;13+7,E2-FB7783,56=E4=6>*!>).,"@%?(#):6G""(.@&2,$;1<0F@*@+E5C5#)/C-3)C#0#/-8"?!.<582'"*C%/"#(4AB33)C&5?886#<117,G&$)=D#=F":6E=+!7?>+B*B7**+8E7<<04!B3$8=H-0*8;G&6'F+A!E-
@r9436
AGCAANTTCATCATAACCCGCCACATCCACCGACTTGTCANGGTAGTTTTTTGCCGCTTTACCGCCCAGG
+
(H2;<76A#>(7">G1H>2)AAC'1EG=17+D*<9=!,4G58("F+A%;(6#0<(!8B*(6>-2=20!,'
@r9437
NACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTAC
+
#5.%$G;!+:6C363$)@4BDC!A0/:DG+/.-EBBA7*%710?E;"#G!&-8(*@$*&":8A7+090<FHEG0E,
@r9438
TTCACTTTTACCTTCACNCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACNAGGCTTATCATCGCGGTACNGGAGG
+
!&)($(+#)$$++##'&!$$%&&()()!#)%&&+))("("%"$#+#''**"*'!(%%')(+#$)+")#*&+(##+!()*"&&"%('((&&'!)"#*(
@r9439
TGTNAATTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTNGATCTTCAAATGTTGTAT
+
%'$!"%+%*"%!*(()&'%('("*)&%$(&%#&*)*)%'++&$**"(('*$+!+%+%&$)%$#+&)&%)+*
@r9440
CCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTC
+
#>AE:42=@?01./$%5<HE8A-,20)H(%62!/<)#!,@'GD+69.#(*H3EG#>9E*D03C+8G3&G3+=33*/+-4=8%;D2E$>65!:'>D4!.C,+$,/
@r9441
TTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGNTTTCTGTTNCAGGAATCCACGAGCTTTTACTGCT
+
+"$+()'%++()*+&*++&+**+'*&+!'*%(#$&'%#*%#!$*')%")()"$$$!!%!"""&*&'!!+!'&"%*")&+$%'"!)*("%(&*%*$(!*###!$%&((*(!&&)%%*)&%"')&+&""#))(*$'#&%+!&%$)('""&#+%$*%!&%()+*!%*%)!%)&$#&%'*!"%&*')$&()((%+%+('#($&*&&$
@r9442
TNNACGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATTCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGNACCGGTAGGCGANCTGGTCGTTGATTTGAGTCTGGAT
+
(%'"#+"**##'()+''*&(+#%+$$##*#$(*+%"+!!++%"*#)"!$&%$'#*+"!)''+'$"+%+&))'+"+(''#*!&'&)%)'!*!%+$!!)++*)'!''(#$##&#('+"+)#*"'()#%$"'+%"#")$%&*#)#$"'#"''#"""%)%*#!&"!+&#$$+&$
@r9443
NTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAG
+
!*=3.G$7+*1>FAA,?'?&&G"C@..3*B@'3<BEE6FC.0#'@#3+5:B6)+/*B;4H+
@r9444
NGNTNNNNTNNNACNGTNNANNTAGACANAANNGNNTGGANGGNCNNGGNGGCNANTGCANCNNAGGCNNTNNNCGNTCNAGTCCGTCATATNATNTCGCTNTGA
+
##!!"$!"!##$!$!$##"$!$#!#$!$!#!$$#!#"$"$"$$"!"!#$!"#$!"##$"$"!!""!$$$#!#!!$$!"$#$"#"#"#$"##"#$!!!#$!"!#$!
@r9445
NTANGNNGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTNTCCGTATGACTANGACTA
+
"(()$$#+$(%%$!(*%+*"(*+$#%#$#&))(&"($)$+%''!$#+')"*("#)***%))(%#))*$*&+*+'%)$%%''(!"+#'
@r9446
CTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAAT
+
<:50.>7<><)5873933)&!&=0;#H@:8%?CD-9?(*@&
@r9447
ACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAA
+
1('(DC5GCE4'G@@CD'3:*55?H@;CD<9#D=,?C&C&E*:43>B<(,EGF=@3&"/9=9?E1D=A;44@;/D#%&/.H',
@r9448
CCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGNGGAA
+
/.C52FD7/>0?HA149*'H9'<-2F1@G089'/9+5;.G7=D;85>FE;B%
@r9449
ATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTT
+
%.;2F908#9!1B&>*?),G*+$+!)C:H@$2F-G'(;)F83/?%8G(9(C$%:$35(
@r9450
GCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTC
+
+0;'?00,"C=61,0C(8#H'>1%G&/*H@7H<&-7?9<9
@r9451
CACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATNACACATCGAATACG
+
928:&0'$($C%0%G>C!,E<@D?,:"(7=4/*>1%)%5'@4+)E676.628A/F%,-H:";"7&'F'%;B+&BA:&892#3AB"8.*,*">A(E,7.,:"10>&!?=.(E4"41-!4D9,F
@r9452
ATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATNAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCNG
+
+)<*(+"H"03160*>'./-:,D*G/(>)'#@3-)1B=H7)G2*3&@C;3,349/:B3@>F?/#5>4%-8@(/F/-D4.3@;C2D@A@7$).'A$#E$F<>:H88.>(:(%@F'.;5D81A>2'@%1@'3C<$6&DH3*H/'$D+1<2%/F*05?
@r9453
NGCACCACAGAGTNCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCA
+
+(*(((**%*+!!*)&)*+)+'*#%+(*&##"%*"&'#$%))#$*"*!("&!))###&%!!
@r9454
AACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGCGAAACCACGCGTGACCCC
+
HC+=9.;&8%95A13$;C#/A87#62DC@8A9D"21+E):10%=?60BE"4%D>:G:B'6936.&<62E-3;EH"H7844(>AB?H+<8.
@r9455
CGCTTCACGCANTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTAC
+
+A!&?'=9-:#-0(&8*&D)*!!?-)AG.+6$8/*?@%<+;F<=EC:D2>,>>.=
@r9456
GCCGGACCGCTATAACCGCAGTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATNCGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACNATACCGTACAGGTTAGAAANCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCT
+
C>71(<AG9BB4,AH*"-CB@C5?10C);&72:?0G+*!),./!8A4F.-B&8?#.#3,76"(>70G(0D&20!'=!4CC+=CD.D!9(>5>*"8-.%+HG:/EA$">6+4'31#"!9CH07<%C!.906@!*/31,H:0:+967D:%;'D1<HCD<FF+-"0*.D$H?)=#C)%2FE::6>><6!B1G=1%3A4F89=.$;53@8H1H7"?C0G8!">H3*H?A36(B.>'E<D;../%A!7"C$<%B>(@..)<=FEH04)*H;:90<F;(%B/7B3B;(46H*"&%$#6;*;-8H2.??A4(;669=1'+2#!H=8?@3G363::/"%?9'(/F/26'B$?B)C6*F>A:>B"8.*?3,/%#/%*G/B2;>B#'+4+#E,"161.A@01A/$E-"#(EA=.5+&9$;@*75&*,=&6*@(HD-A?B.FE<@+<FA)B?C.5E,D;A""F'&E%3FH.0G3=C#(=84//&
@r9457
NCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTNGCGTCGATTACTGTTTTTGTAACCGCACCGCCATTNTATCTGCCGCGAAGGTACGCCATTGCAA
+
%('+!%)($**($&#)$"$'#*'*('!'(()"!%+!(((##%%$&&#%&(!$'+"'&"#!'(!#"*)"*")&$+#"*'$$%%!+&**'"#&&)%+")+&%$+$+'+(!%
@r9458
CAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCNCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAG
+
E2;-#)1G#B2@432,-7BH)7<H3"&)DB,F.+A%=A,=4++8-E)C=$7=(!.EA/B3,/(2";>>B1-,=21@#@DF4&9&;91";E,;>;%G.4#,2)*%H6B3*8<@*'-2C5':&5)8%A*#;=>7()A7;;C@H=7*F%9.GH;8>.=G$;,E;E&G5F'%$4/8HF%6=9G,<>5+40H/E(F7E>3?<(>:,1.E483<C830"9231+>(:!+F%1?**'=>$/$
@r9459
GTATATATANTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAG
+
$!EE3;>?C8''.)CA/,;&6BG62G;<2=@2$2-@@2!6(H0A3;(>
@r9460
CGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTNGTAGCGTCCGGCGNCTGTTGATTTGAGTTTTGGGTTTAGCGNGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAA
+
F:85$-H=00#(;#82+)'=8C49<=8)2&++,*:?-'H""!88+'-9%:/;D-D:1*'%=:AD4:6">"5*GH$5G3-,BAH@HA>G(=<:,=F6&B;E>1&9=*H>1;1668B4#C#7/?(1;<03<#0)$B---AA1
@r9461
TTCTGATTATTGGAAATCTTCTCTGCCCTCNAGTGTGAGGGCGATTTTTTATCTGTG
+
;'FFE*1-8G5.A'<3'0'341?-+@D5*6C<"="F8,6,0:)G$-!-473*=%5.2
@r9462
CCNGTTCANCTNGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGNCAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTC
+
#'"&(()"!($$)&+!($&!#&%*%#$$+$*'(#(+%%%(&+$&(*'+#(%)(+!()*)#&""&&*'$'&$#($*&&*)%%$*&*!%&$)(
@r9463
TTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGNTGTATAGTCAACTAACTCTTCTNTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCT
+
(<G*%+C?9G$2A%5=-8#>!E/76F--%F@;*2@?F%?>9D=76B>!:A90C(?0D(+#G%!;B,?1.'!EB7"4E3*C?1&:4DA.G@'B,A=+G<'G==.E4267,:9(<C.4'689H$+96,8'+AAF/<5E'4#;'?8;B>,F:+E*&7$7,-00#E9!+B(
@r9464
CGTATCGGNGCNGGTNACAAGNNCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAG
+
!'&)'#'!!)$%&!)")$&'*&$()%%)%%+!&(%#'+)($(!$#"!'$*()#!$)'$'#!)'!$#*%(*($!"##$$$&'+$#
@r9465
AACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATA
+
EACE'0'8BB$1%-+)*-,F?+!.$D&/"=1)5$0!)7+#BB9*7(FC94D!/..,0F4G7=.#!9<0+*:>0G:+7)G@6&79!G+7E%DA8@9>A/;5E57>:!145640'"''&,,%+'%)1(#.)"B$1EDBD;&/&0%/$
@r9466
TTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAA
+
)4$4B4G+9B#'0B<'H-#EA"?50H=$:>97.C*)$"5BHA>(G-(H>"B$2&*.F"/5="6176-:GBD
@r9467
CTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTNGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGA
+
8:'D7:?F((+&8C>-B1B*,3.GH<"5@*,85/!#:'>:(D7>3,B,C30$=/*9'*AG%3;3-#6@C2;:1@A!"DGH6B',#0)881(25A:=(GB+1>=43:522.&=3/H'64A0&H940CAB@A.3&$A(4.8++
@r9468
CAGAAANAGACCTGGGCGGCTGAAGACCAGCTGCGNGGGAACTGNATGGCAGGCC
+
*5/4AB"@C)=E575B@B@6?B*$G/%>72(/<"+*&;-?<(F";5"!(02E==;
@r9469
NTTNTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGC
+
$H:;B<;-'>)7%&&H?17&=;"(*,:%<F@<=..@#"+>DC@)0-<C.'"GF+F
@r9470
GAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCT
+
?D#C9/>&+F?87#1$H#F7HB>.*2"A@E%1C1395$:/%AH+#'$'C)E)B)->D5-5',5D2>'8!H>H=*23E<)
@r9471
GATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTANTCTCGATTACGACAAAGAAATTCTGGCTAACGCTCTTGCCCAT
+
D4&%7D:?.&B46+4G@%/">9.E'0)%C-)5&<1$69B@<4+5A<22)3:&>0<45?5-='7+?9GD4B%8@9;#8.A6E:D>3H)E(;6:1)G(*B058:)@:/.E
@r9472
CANCGCCGGGTTTTGTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAA
+
((!('*'&'+$(**)$"'!"+#&!)'$"&"($%$!%%!&+(%"'!+(&$"#++('"'+!)!"#'%*+()'!(&$!'%&"$)($+%*&"'$$((*!#)#*+&&(%$"+)&$##$+!!+*('!+#++$*&*(+(%"+")#$$#(
@r9473
CTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTC
+
<B(=#&+93B6+9H)>C(<G&5;&C!...>)$9%0:$1%"#@DGD",;
@r9474
AAATGGGTGGATGGNAGGAAAAAAATATTGNGGGACAGCAAAAAGCGAGGCAATGAGGCACTCGACTGCTTCGTTT
+
09EC:,2?$D&%"36?-BH05?1.CDC8A)E(5C+::82*+('C<9EG%G(<:+=*=1D;!%0D&&.<A1),::59
@r9475
CGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACNAGACACCCATCCCGGCAGCGATATACCGC
+
0/9#!C)2GGH(&3$:5#+6;GB)*GEG27H&5B+BB;1$%D7'<C;#%%<:%$2-268+(7.B.D&:,;&42G7F0$FB$H9'3B#;D&:>B',1@4?8<1<B9'+B>F42D-*45G>2
@r9476
CTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCANAGTCACTGCGCGCCTGTGCNCTCTGTGGTGCTGCGGCCAGAANGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCAGTGNCTGGTCTTCGCGTCCGTGAGCCTCATCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTNCCGCAAC
+
+.@%06@/+*$B)4,-$4="D"=3(+/G)+?21:+90-CF#)3'!0'!/:#14&!F)$(<<B?!<'->*G/5=('6$/E!=B!*5+@')!;B%#+,:73B+&F?>B29B0=?E-'7(9+0@;@FAB3'/)@!&30%!2=%&2)>F=D8,&":?':2'812*H&B/><5;>,6C2/5*(4)/;:%F?.0873:FF:7C.C:*G';&.9,
@r9477
NCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGT
+
'-10.!@12F7+'4*#/;30BH#C<"3$*C63(7?*AD).=AD1#E9A#&F"3"&&.,B/$>+3/%,):5!6E!?-3,F5935@CB3>BB=(5&43>/B72&
@r9478
CGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAAC
+
!H?(*"3CF!9-D7)'"/##&67%!0$//4$H#1"?@@76G8BF:)0(F-2
@r9479
AGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACC
+
,6:)8'>8/?BE1234AE+&>A&>+4*E%C"2>520(1!40;9,123E9HA'F@%397+H
@r9480
CCTCNANTGNGNNTNGCNNNANNGNTGACNNNCCTNGCNNGNANAGNTCNNNNNTCTCCATGGNNNNNNTNNCTCTNNAGNNTNNTANCNANGANNNANCCGNANTTCATTGNNNAA
+
#!#"$$!#!!$""$#"###"!###$$$$"#"!!"$##$"#"""##!"$#$!"$"$#!"#!$##!#"!#$"$$$#!!!$#!$$$!"""!#$$#!"!$!!#!!"$"#$#"$##"!!"$$
@r9481
NANNGGTTTGCCTGNGNNNTCNTGCAGCACTCCTTATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACCANAGTGCTGCCGGAGCCTTCATAAGCAATATCANCAACGACGGACG
+
%#$'#%&()#*$!#&(!*%)'!"+&#$+!'%*%$'##&#')#$%!%#"'+*(%%+$)))*&#!)&!%*&")''##!+"())"(!&('$+++"$!!(*'$)%")(''+!+#")&#*+%!+$*)&%*'("$&!'!*(&&'&+(&(%!&+!%#"!$#%%"!%""+***+($%'''"'#"'#&#%!+#('%*')%'!+++%#(
@r9482
CTCGACCAGACAAACACAGACTGGATTTACGGGGTGGNTCTATGAAAAACA
+
"3+:G3)/<!6<HH6+4=@F;6,FB!";E-B4-;8#/D-2&#)9:75&#%'
@r9483
CTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGATGATTAAGAAACAGGNGCTGGGCATCAGCGTGGTC
+
D:.;&:&6+5:7%06@+CG"9(A3>G,:2G1D.#-3H<#B7F84C';9'?DGG4A244'+=.BC!/>BA?B7/*//2DG0>C7+&EB41D1/@%;C:.9*+<
@r9484
GCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACNTATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCCTCGGTGCATGCC
+
H+F78=<E83,:&,84FB9E?B+#%D($3D>./<B>=34#/9+>%B1;;&#*BB<<G%;"B.?9!F->#="!5.>:E8G%-AGC&?8'8C3&E04GE:D3:6D"0C%%B#'$F/&?38F$B=A."F/2/1@37G"B.C+;*C8&F)?+(9#G7)G+6F-%5.9%9/&H@A@A#8G%=.6.0-?H!E8>EH<!9"3%0%5$46++.#96'$1+2!8$;.4"/<'F/$H*$*(D6!FD.FG7512=D88?"DF:#.3BE
@r9485
AATATCANCGGCAGACTCAAAACATGACGAAAAACCANATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACAC
+
5+/G?F#G"AB4H$2<***+286=@?(EA*C#.$E,.:+*%)586HA:"9F53F%!HD;+0F)*46/#C>F/('@117#<;>&+
@r9486
TCCTCAATAGGGAATAATATANGCTNTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCANTCAACTCACTAATGTATGGGAATTGTTTTGA
+
#01#%G:D+:G:'%F8,=;F;DA@1*:DF4;$#302:;>8$)98H#;4/2,%08;G+7#G(3&9"7=/8D!"?(,6+-2$$:50=HA=H9=C?2"G$FH-$
@r9487
GGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGAACG
+
F--/3H,&,7F1>>?C4+9D&97G)>FA7<B0:%.*',;8:9E)H)*<1G*5.$2)@4+E/>4'
@r9488
CAACTTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAG
+
H4$93H?=!.G,=#$6&'<@=)E13776=20$BFB'>>;,&&$47E109<1C1&F6BD(%914(.GC9'4.6H='B
@r9489
NACAGACGCTGCTGCGTGTGGATGAGNCCATCAATAAAACCTATACCCGCCNGAATGGTGCAGAAATGTCGATANCCC
+
#+"#$!#'#)*($#(++$+&+($*)$*((!%*'!+(&'#+*+()"#)##+#$)!(+!!*%&+(*$$&%(*&'+%$)((
@r9490
NAAGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCNACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGT
+
+!#+"&)")('**""+%*'+(&($(*$+"#"$&$("((&)&%!$###"(%"$("$'#)#(""#%#%)(&(+++&+')('+%)%()!""*++$)&#+(#%+*%$&"%'(($
@r9491
GNNNNTNNCAGNNNNNTANNCGACAACGNTANCNGCNCTNNCTTGTCNNNCGGGNNNNCTGNNCNAGNNTTNANNGNANNANTAANNNCNNCNNGCGTGTNGNNTNNNNGNACCNNNTGNNCNCGCAGNTNCNGCCNGTGAGNGCTCNCNNNANCG
+
$!"!##"!!#$!$#!####!"#!##$!!"##!#$$#!##""""$#$#!"$$!"$##!"!$"!!"$"!!"###"#!$$$$!""##$#"#$#!$$!$$"$$!###!#"!"!""#!$#"!#$"#$$####"#$$#""#"!$""""$$!#!!"#$!$!"$
@r9492
GGATATCATCAAAGCCCTGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTA
+
D=.G4GF+//.<>.-21A)C+/(H<$B?$E4#FA0/B3&F)5#-.(>E;?(;4(=51.?BH*H2!G'A5FEG.0'!:;*(9*H&%#"
@r9493
AGTTGATGCAGATNAATTAATACGATACCTGCGTCATAATT
+
503G;".)<2"*G%->A1B"%*F%GD0@6B9-B/.:D5/6$
@r9494
ANGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGAT
+
$%"+(*(*##)*"#"""""!%!#*!"#&"*&+)(!#+&%+"(&
@r9495
CGGTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACANAACGGANCGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCNTATTCTGTGCAATANCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGAC
+
&$!<65"99>@BA!04C:<#+.@F$&:4A>+3'@$>=7A&+:C1>F<*"%2"'5+>;A'G9DHE0!7?&"G/H0*,99$G>+!F53.8H!2#+@<,!:#$#'B+26#)<8(#6!)C-%8*%".%09)%5,'0&H1@471&5F:A<'%A(!",D->B(0E8E><>G,4'H;C"%G:8F6,<;1;?"7.0D2>$7$4=5@FE$=),?0$<H4.977$2'?
@r9496
TTGATGGTCGCCCCGNTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTNACCGGCGCTGAATACACGGGCGAAGAGCTGGAAAGCGATACCTGGCAGGCGGAGCTGCATA
+
HD,!3G9!%2%7,0&'>#31$$*C./F$2B;/"FHB9(%/>77E+<-9HG(9'2=/4>E$4)@DHCB)51.84&CB>>131GHB9B#>44+*=G?:HH+4<(:!C3&()&D#(,)")-E$
@r9497
GCCNGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAANACCGACATGTTGATTTCCTGAAACGGGATATCATCA
+
?%@)7+;E,.739<D:H7AA9(H$B4!"3&C/)0#G/)#4FC(?%*"DH'31$)23"(#'<!.4>8@4A-03AA469*)?$;%:=;5:%G!::G
@r9498
CAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTGCCCAATGATCCCATGCAATGACAGAGTTGTTCCGTTGTGGGNAAAGTTA
+
&B.%:$&A/DHF:H-G/5G!&$4@/:((,C?G(16,4=$D-DG=A0E:H(#(A&>?-'5:"4B$E&<2=G>++=B,+03/7H#=4%?,D"%$CE%?CB=#.0'-<$
@r9499
CCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGATCGT
+
4B/*;99:19&*/;6:9>,H!-@;8,77;6.502E3D61"'?(")<1H9,*<+,
@r9500
CTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGA
+
&+"(#+$#$$$&*""#++"%!+$%)&'))&&'$"()**'#!"!%'%!$(!"&*))$$"*
@r9501
CGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCNATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTC
+
1C#87#6(,9G/@H67@A6''E2EA7<6"E1E41?=#H%7*74>'H55-6?E+*<DE37-:65,'-*!02.?EG'11D0"%EH51)C#E)C")19+8AD78?B<H&94;&A<%4=+H+A"3HC=B*BF"<,/<5506>?0,
@r9502
CGGCGCTCCATCGTTTCATGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCA
+
0"-/"*>91;DA?"#0<H:,=$F=@E'(4D&5E7:H(@@#?=:<9.?63'"5!#/$-#;*7)A?/*0=
@r9503
AAATCCCGGGAGNTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATAC
+
4:*C!B)A0=E$*)<#,+$A:.A459"/GDE=2&G+%&13FA18+57-<!BC':2,;9*:G=F7(7D3&C(4G.-=0D;4-4<*D
@r9504
TANATTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAANCAATTCCCATACATTAGTGA
+
$&$"#+!'!(*!$($""%++"'#**%"%"#"!(*%")!+#($!&#"'*##*"#*'#%$%**$"+#')")%'*&+*"%#'"**#$"))++"#+(%+
@r9505
TCACGGACTTCGTTGCTTTCCAGTTNAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATNCTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAG
+
/>H@>&CG-1<!;;C48C."=+E?(*72C3D*<!B-'17&8=/.%AC&106F:=3FH:;;ABCHC??FH+9=;>4B$2720?F.1>,E+<#.=./!C<!*&F;8":H
@r9506
CNAAGATGAACNTGTCCGCGCCTTTGATTTCTTTCACGATCCCGT
+
&(A<*9"22D!1;*97B?(?:%32;(#?#E7)4%6A>*)B>+-F2
@r9507
GCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACAACATCGA
+
F8F63BC>CH?;F!D0(A;CG33$)E1E*F)%%#F#G,$9#%@;8*.G#A39=B!D
@r9508
ATATAGCTANGGCATGTAATAATTCGTAATCTTTTAGCGTAT
+
#D%?5%FE5)@:#B+''9&,0-3HA(.@9*E'"'$@GF.3%,
@r9509
AGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTNCAGCCGGTCCCNCCCACCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAAT
+
7,9!B@&@C3;4($(3>#%C'?(%<(,6D%D'04'0C5AC#A.E74!43.,.=?&DA#.G<'53*(=!!E24C(3B=,@0-7AB4;#$&?71(<9492"6147$7B:%+9;$-$""F7D:=<%:B91=,(E4/>H=*2-5#G)FBE<8A;%77$'3B5@!!0=8=)$D97&*C&7(">46@BH!#);7DB$(&.E07#FC43BG@>+?25-0AF*6*A#"&;3#F1/ADDA,027%3+G;3@"67CG.-;;5C
@r9510
CCGGAGGATGGCAGCGTGATTNCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCANCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCGGATTTCAATAATATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCC
+
A(%(?#80B-!0A+@.4-"$&77A"@4/+-(@1B:G<8>$$E8.&@AD?$@%!DC+7)))5/$:E<3C*DBA!BA60?5&#1*"(%(D">#;A"50!?+5H+D?'2*?#(0('?<C38</#?@$5:F!.44-ED5E6<B4,C0A$7,=>!.FG!-"'?@5"3+@"
@r9511
GTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTNATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATNCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGNAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCNATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCCTTGTACTTTACCTTCATCTNTGTTCATTATCATCGNTTTTAAAACGGTTCGACCTTCTAA
+
(+$)%)))#!(+")(+$'&%'+$"'+"'+%(+#(+"!"(+)&**'(*&&$+)*"+&%#$)$$*$#""(%$!"*)(')'!(%"*"%&*#"$(&')+"!(**&+')%!"'))%&$#$!++"))$'&'&!")'##$!$%))!!))!(!*(#*'"+)!"%#'*+)+!(%&'"(#!'%)$)*!'$)'*''('+*!)!$('!+)')+$)"))"%"+)""))&#('())*&&&#(*#!&"&'##'+%'*"(%"'($%#+')$(&%"(+$$*$(!#&&*!"**'!!"$(")##!$&'+$&*$+*)!"*(()(&+$))(+#)(''(!&$!'!'$#'!+
@r9512
AATNTGANNNCGNCANNNNGANTGNACNGACGCGGGNTNGTAGGGATATTCGGGCAAAAAATTCCGTTGCAG
+
&)&%*(*##!$'#$((!&"&(%'%#"$"'$*!%"'*!'$#"+("($!#(!&!&&!%$%"&""(")$!'''"(
@r9513
NCAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGATCAAGCGCATGGAGCGACAAAATGAATAAAGAACNATCTGCTGAT
+
$:%=<%?154<1F.:%#E<0+<$)(2/HE$!+9-B!G6:+!&E%,FC=-D1E-H)'A<3G5?9BE$./-6/5%=7D3F?CH@<5'>
@r9514
TTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCNGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGNAATGGTGGGGGCCGTCAGGCGCTTCAGGAACA
+
+!%&$#''!!$&)))%"''+&+"+&%*$'))!#'()"*$!&)*("#%"$((%)+#$%"*%*#%$*+%(!%&%&$""!*$!(!&)((+*++'"$%#("+*")'*+$)#"$+%$!$'($'$##%#*)#*%&%(!%)'*!#$(#+%$(&&'%&''&"&+'"%%+$*#$$#'&"+
@r9515
TGAGTCGCTCATCATCGGGCTTTTTGGCGAATGATATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTNTACCTGAATCAATGTTNTTCCGCAGAACACTNCGCCGGTATCGATATAC
+
$!:/#&.036-@!A$0$0$#;=<?BBE"$5#&/*0AG@&3*HE(6*(H7()2A<()&D&+'C1/9#E*-->"F9>16@6.3762.C+H,!B.F/!0E,$%CCE4<92(AB+25+G103+<%?;
@r9516
GGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTT
+
3GH$-/(G4/B-6#7>F(C6;(*5@?6G0F67?,=&C?5G)?(1G%/&<2-&0E"*<'D
@r9517
GCGTTCTTCCCTCCGAANAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATT
+
/11$BGF;,G-91/9"43EF9B?%(5,,*H(:>:40;*36+)7%H-C.%H6G'*9+B8!><H>'$
@r9518
ACGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCNCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTTTTCCAGCGGCGTCTGCAGCCGTTCGTAAG
+
"D9A%.%D.9HCFCE;)(7+(@E="2C=39*>-"?F!"&G9#2.2&>/5#407F:1($-9G3,&:0C2AF8E.<A!/009HB/8?0H.)E54DD;?FG9=#5;%#>+6>/,8F.$.GF=&
@r9519
CTCGCGGCAAAGGAACAAGGCATCGGGGCNATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCNGTG
+
?GHG2#0-B48:!A.3,$6&E&6>0"&.5*9B#8#"D!;+&(/&C0$<)B(09=7&;3!G>"C8'E=100@>+(4$.E-
@r9520
NCNTCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATAAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACNGAACTACACCATTCNGCTGAAAGCCAGACNTAACAGCACCACGGTGGTGGTGACCNCGGTGGG
+
%)#*"'++''!($%)%()!(%&&*!(#+#+(!!""$+"+!&(%'&"*(#%*)(&%*%##$*#$!%#!!#"'%)%#"")%*$("%#*!!&$(+%&*%+&$&!%&$$#'#+*&*)'%*)")%!&%"+#%&+$")%%+*)&!!+%(("'$(%&(!%+&(&!+)')')!($(%#+'!$+&!*'*'#('"'$(#!!*+
@r9521
TGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCNATAG
+
,841+)%E?@$";9>F9(;CD/E6$51#,3#C%:8C"*=@3/=*(-)4?<'8D3.$F":.+92,,%8G/><!"3?5,#7--7$9(05#'&$3-47?1=1#$H/
@r9522
AGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAN
+
$'('*+)($("%&)))$(&&&!#!)&(+*)+#&%+)+)*$%(''+&)$'*!!+')%#(*+"%!")'("*
@r9523
TGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCANGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAA
+
(@*D%7.5:*>6(0BB>=3;+$0%E&D<:!48?/,HC$3(0H6!GCED1C>B9$'/C,-D8#&4%#!),=2=B80,$<&!+A.&:/D@+5*@A//8*=HD%1A"ADB$E=#D(;:+B;B@/>EA="):E#?%9'F3G*#</,CCC%<!%&&(;5*
@r9524
CCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCNATGCGGCTAATCAGTTCGACGCNATACGGAACCAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGC
+
D%0->,C@9?<F8-$*).)">%8<B>E98-70GAF);D!?D6B'@31,&2;7/&E3G*!<3,!H>:>41/5';H'2-21!&,?238'7)87<;5#9=>!37A*4F8,H=;$!,;:@/)F%/A-/3==29/%5B>640$.4:EG*26&5B7E"07D=84'0/46*$0GB?H3D"<&,C*=!ACB8/@;3%F11$@0B6.),!:(;)*%6(*();<$;+(='-$%69.E"=&?2'G>F(3'9%"<>71$>H98,+6#FF>3
@r9525
ATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCGGG
+
3*BG(4HC/E=""3>@09*>?<8?)BD=)&7!:+'H/D('"F"5G#5(H%C48/171B8(1F<:D)7+4'>>D!B#00FG@"0
@r9526
CTCACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAA
+
3F#H3"+B"-@F:B"@83&/+GF&2:+=?$?.+4!,<6/8/5;0G?;"C#.+5<220&:G#.3@/HH&+:D0&E#3(CHB2C
@r9527
CCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCNGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACG
+
CB6#$9?52DD@=G,9=9('1)+);"&;'E?:4#E#%E/8!#.8$0C.'7?'+&GA.7&,G#6??$%*%$;94<-B:2=!#6!=!1>)>4>D!%6FD%D749H
@r9528
AGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGGGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTCCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCG
+
9955;3!#<8,C09$CC"0@54/0;=&#A2*HD->;A@9;&78F2"4#8;?&DE$@A0#!;6%,2&:3G3@)-H843=:,@!/:'H<</*?GB=*.8)F!#=E>-159=#2!2B4+'?HBB:,-$<376B6>CH&-:4%7?6+@,58D/3#1C<:*H-C-#'!);5C8+)+F%%86C2(#$<B<(7?>F?6,<F&-*D9%2D-*&#!9B"@0;!0G&!5"6!$
@r9529
ACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGNTATCCTNG
+
+A3>,*)&5-%8E8/<=.-/*42DG3:6!601B,6;>7?!&1FC3!)=7
@r9530
ACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGTGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGT
+
8,/+8/($#%G3+&9*;;.=%"EF9517#/&D$;95:B<9:@A;/7)F@531:C6>3BE7-:F#7@2-40(-<A1;7(>>8"/;5H"&/'73%F
@r9531
NCTAAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCAGAGTTGTCTTTTNCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGNGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCANATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCCCCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCAAGAATGNTCGTGCTGGGCATAGTATTAACAGTCACCTCAAAAGGTATAGTTAAATCA
+
"#&&+!%!+'*'%'(''!'%!#)"')&((!")'($$%(''&+%(%'!!%)!#"(')()*#'##'%"$!#%#'(%))"$&$&%()(**$"#$$+'!+*()$$)$(*"!"+'&*'"%"!'#%'&#%*"*&%!)*!$*"'((*+'!'*&*$)(#"+%)($)%&)(&'$&"$**'#&&%'%+%*)'+&*'*%"'"")$#+*&(+#+''))&+#$&&$'%!&%()&#*(()"+%+&)(!*&&*&$(&)#)*'")(!#"'!*+&(#'$#*%"&#)*&)+++%+**"&&+%$"++"'&%($+(%'%+!')'$%+#'#)"&&%#(%)##$#+%"(+$$+($+*"&''(''&+**($*&%#!*+%++"!''%&%%&%'$(+"'+%*(+!&!#%"%$+""*%&)&!%"&$&&#!((%+&'*)%+))&!"()'%'#(%$&")!$*)")"(%%"'$!"%*%!)%&$!&%%)!&#
@r9532
CAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCATATTAACGGCATGATATTGACTTATTGAATAAATTTGGGTAAATTTGACNCAACGATGGGTTAATTCGCTCGTTGTGGT
+
<'D-,19D>:89$GD!<>"6H+8*0.HG2*63HCG5E!HD2&-3#4<B7*%D0G!83A4,2$E=2=$7'5@FB,C3F7";H:G+-((450FB944."!=!@CB67/FB,'E-<G-H&;GAD'4-AG!=7=
@r9533
ACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTNCACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCG
+
3#E6-/@E2=>$D1B%;=(;)7#*-;?DF?FA'.0%'B2C56.@$%3D,1)!&.;2;"DB-'@4).B9/GB)(?4(?A'17=<BF2E!13/F,-2"G(B#=6!&,$0629#.=E,=*E+5+873?!A4.<'+G!"<&@#9>>:A321*><,%B90C@7C9@&A&&4C#!F-=2H50>=%C+H?%;2*!%E++'5CH;)9H;2<$<G;G!*&-,-,&>/)<*623*/!+.*C.A:%?H3>#$AE1
@r9534
CTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACGTCAGCAAGCAGGGTGTGGAAGTAGGACACTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGNAGGATAATGTCCGGTGNCATGCTGCCACCTTCTGCTCTGC
+
AC?E9&"3)&4E#;!0&A8CEG*'CD@E!!81,,5(/<B8E,,:7,0*)=E*DAC6(29#7C.!>G*F2)%DB4630C4@??'@85G0&G(#4><H"+EB:(#3DA92(;3*/+DFEC%4"!56D$+96B;A<"5;9%0,/-%"0/9+)5%BC#H)'0=%EA!%H<D,&@0<%'72,#:4?C.4$1#2F-+5+=6#/(%@GA$=4!(?F5G1DB$&.?G%299'3)=9.5:?70$F#=2/AC&%61/@05;;=0,5;45?4+#-F3/?E1@/'C7
@r9535
GTNTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAACACAGGCANAATCTTTACTACCGCAATCNACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGNTCGAAGAGNANCCTCAGGATGTGATGGAACAATACCAGGACTATCC
+
%)&*+'!!+%+*)!))&!)#%#++)+%+##+)(!!))*"*!)"'!*#'#&#&+#'")!!!'%$')%&$'(!*)"("+)"$)'!(()"*!'')'+"(*%#&&+"#+'!%%!+(+#%)%*+!%"+&%!+!+!%*%&#)!"%*"'%+'%($(("#%#%&($!!)#!()
@r9536
ATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGCTGCTG
+
DB75:D)&!+#GC(9G,827<?F#0G9)+@?#((5,$H*:?3FCGD?H.'6#/.$!1%
@r9537
NANAGGTGCCGGGACCACCCTGTGGGTTTGTAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTC
+
!(+')*$+#$%'(#$%#%*)#*!$'$"!'%$(&$''$+'"(+!&)'$'"!+%!+$"&#$()*#"'%
@r9538
ACCCTGTTTCTCCAGCGCAGCACCGTAATTACAGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGGGCCCATACCG
+
49"4D:E15*!&$:=9-5?6)3,,!H/C#7>C4)'=E01=554#6$4/36/#06!+;<@-$H*<#!C.>.*FHA="4B+82'07-$&H74)!B)<'6@8+6:B7D'=",/:<GGDA%5:>B,"H:7,AF6"$/(68.G3#)6?967B$<9+-&"!
@r9539
CATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCGGTATGGTGGCCAGC
+
GD=9D'*10>+-%"==:DC9(6HF/#A9A(,7F/>)-6:(!,E!>'>>.B9+$F$<GFCC@.:@FB)F90>(;2$"9<*D91?2=@":"=*C+'>/D'2=*%F($:78A&$9&G'C6,"!G1#%"8"76
@r9540
TTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTA
+
%C?4H"/9G-C5'92+(6B092?G""(5#H!:(7<%'!?$
@r9541
CACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTC
+
,/"0BDE29&&15A?=C;,<E'781&#<@9,.B*162C(F7=/.@:
@r9542
NAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTC
+
&-606+<!*-+":&>3A1+E=GH$".,3%FD/;&&1?8?((DC6.40-/%41@3$5"B(?6439G=353.@'1"*A*0E'E'#
@r9543
AAGNTACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTT
+
C=2.B<',</:;AA$9E46;HGBC/+H#@;<.H7@,--0H<;6%9F#6/;)5!13"<-:-A<$835&39,.C.-/;?'9.C,6:4'>#A)!=53$73*F#+4(A5&;-91&""=/H9'2#F),5-*+?06"(4F?81>4&F7+
@r9544
GCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATNGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTACCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTANACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTNG
+
6F)EBGF6E3@4=*::#9"$.(!3@F(.*E>G@#(*&F(61(#D#/-EF%3)E+4?&'6=!2==+)=8#0>GGA/=7&1+8D.0+GA#BB1)$)AG9$+G"8;4!*;<@E4,02#4E$'>($.C!0B)1B)@0D'7!#2106G;B.<-?6+;32"D##*4=F=.;(%,$!"<>96+)GGDA,3GFC(;0,4)@%<@2+)(GD</%!#,/$>'"BG!)?23H?)60;,BAAF477!'&E:@@:2DB%;G;*C4AD;4'A<F:$#&=:#D-%#2.%6&B%/8*"*3@?G/5,/%)9C1:H;<G@5?6()@$92;*%%:&7>?C&1/C.'-A&1A4;>,5$,=5DA57980(A3)E;<@B=>3%2'*=,(00#C#$45.D7;$AC$-@;C"+3;A=DFB=)A%587%"B84.&;;286(E=(=-(-C(*-6;GA2A?5'=)1=&)$1+#8G:?1G3
@r9545
GTNCTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGCATCAAGA
+
#'&-+:9/0HBC'(,E87E('6B@&;7F6=&C&"0*8B+.:+6=;@;!D,<
@r9546
GNNNNNNANGNNNGNNCNNNCCAAAGCANGNNTNNNTNATGGNNNCNN
+
#!!#""!$"#""#$!"###$$$$$"""##!"!!"#$#"#!!$"#$"!$
@r9547
GACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGATTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGTATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGCAGCTATCA
+
+!'#5%<*=*6:;@$#%'EE:='=2%-'HG@6.H<6-AG1-G5;7/B$FDE$10BH%,0C",'8-"#,+<C<C#6:G(8!9">(-C?!>B2;'A%'B3>CBH058=GB75<7;=",3GBB+*?=!>8*#:,F$*:B*/CF/#25?:0(D;<HC>4/
@r9548
TTTTCACAAGCGTTATCTTTTACAAAACCGATCTCANTCTCCTTTGATGCGAATGCCAGCGTCAGACA
+
>'2>F3GD+B$6:03D)F;1?&B0D#0!$'C62B5#D,=/"(E3?4:;-9')%?8/E,*63@F/6A.!
@r9549
CAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCA
+
92=D?;,@/2:BC-F$:$9'F127E<?G"9@C=2:5"84437+2?;C>!E:5&>;(#;?4>.G>$)H<-%?@<1%/#4F49CG?%8&7;
@r9550
TTTTTCTCTCGGTGCCAGTATGGTGCTCGCTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATA
+
+(%$%%&"*!*+++)%"""'!'&*$&!'+&'$!+)#$()"!''%*%*(+%#)$**"+$!%%##$$**#)#&%"++!('&&#(*!&*+$+
@r9551
AGACGAAAAAACNGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGNGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCNGCAAATGAGCAGAAA
+
,=;666G9)52571(#91-A*@6??H9$*0?9)7-E;)/;-,)'HG/+27#%"$7'1F?D.;,C@?F&485)0E#0@E98<+1,:5?;>B,->9=""D6.8/4/:A:.AHFE.,)&"%5GA&+'?#F:/,5,HE.1'(0='?;*E!$E>9>4A
@r9552
NNNTTAGCNTGNNGGCAAAAGATGAGGCCGGAGATATNTTAACAGAACATTATCTATCAGAAAAAGGCCCTCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGNATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCANGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCACTTGCTATCTCC
+
#!#)))')#)(&%)+%#()&%$%%#")%(+!&&&)#&"&%'**+(''#'$!%'"%((+!''##"'"("$$*("+')""#"$*%+)*)&($&%%$)%$")!!'$"!+)$$&#"()$#'!'*%*"%*$)('#&#!(+"#(!(&$!$!&!''**)!++*"$'+)$#''"'$*%""*$'!)*$!$$*%#!!!&##%%$&'(#("+(!&*)(!*(*%""*(!"&$'+(%'$)!+'##)#'*%+*"'("#"%)&$'%*+"+&$($))$(+!**!%'!*#+$)#!%%+&+#+
@r9553
AATAAATGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCA
+
8E:BB/?$(+AHD6*%4?3)?9$4?0FF)<G?'$E1$C&F#BDG8+)93(E-7$0%<#,6F50#:$"B-6-0
@r9554
CNGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAG
+
()C@G<?/BE5,"G,))F'1C<C>&!<=F>5E"+?H<E3!B'92A#.6#G.0?F/E.B4+'4<,+!$/+7,.;5C+=!@33):=B<8AF!6"D8;?9"#6*@!!2#"!2=?2@,':*#$)
@r9555
CATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCC
+
1D4"F"8#H@8&<F"&6'"=E/"!5=D**+)$H%@1#=1.H;$@6$,1&0>!.C!0G0A?G:#435A3@%'>',$H<'
@r9556
CGAATGAACCAGGCGATAATGGCNCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGG
+
,/58?@"*%8&/F.%54"5*A41+7E8<H.&.=!!6B:&%(?#=C6''=+$C9G3HB)2-HA&9A$?42#F.4%8@E9,>A9GB6)0A8+137&<!<6'>0B1DB
@r9557
GTATGTAATAGAGAGTAACNTAAAAGAGAGATCCTGTGTTGCCGCNACATAAATTGCGNTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATAT
+
+%&("('(&*(*#(#!&*)""&'&+%$'($&'&+("(&$$$)$(!&!!+($**"#!!)*'%')*)$!))!!*'(*+&)'!&"'(!*(!$!**%'(&+&$+'++#+&#*)%$+(#%&%""*(+#!&
@r9558
CTNCANCNAANNNCNAGTNNNNNTCNNCNANGNNATTTNAANNNNNCGNNTNNGNNNNNGTCGATNNNNNCCANNGNAANGTNCCTANANTANCGNTNGNNGGAGGAACNNNNNGNNAANNGNGTNNGN
+
"##$##""$!$##!##$!$"##!$"!$#"$"""!#!!$!#$""#$!"#!""#"$$#"!!"$$#$#!!$!"$#$"!!!#""!#!#$#$!$""""$!!!""$"$#!$"!#$!!!$##"$!"!#!$#$$""$
@r9559
CTGACGTCCTGCCACCGGNGAAACTAACNACATTTATCATGCAGCCCTGTC
+
:*7>69+C+/-=9$D7@&71D3)97@-4-*%=2:44A+(=;"71:"GA'F?
@r9560
TGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCA
+
1;!A8->.";B:#&@?0>F(7%873$?0EB/,:'24<96?B3.-H<@F1/2-43<*>
@r9561
AAGNGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTAC
+
8%40>F0."6,'-8:'4';8=<20F"+5$,F)(2D1=/B:$<4&1"8&1D@3>->G6;*)-0A'39GF:-%<B7?A2!55?3&AG6*D9'$:)!27@456;*4!8,)$:':.1
@r9562
ATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACNAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCA
+
33?7?98?14%@-"47,7:>$F$F@7EG&BG/E'C6B4@'.+**0-H.&G0C>-'%66.CA9,?+8*G26:+G63E4?0*?EB,9+-@A..0/.7G).4C)&/"#5!E6H$):*!4+5:;@-:@B3F%!!'<&;6"'!;G;-<-3"=-'9@D%829'0B>#4CFA=F0-8-=.3
@r9563
ATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCANCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTACCATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTNTCGCCGTCTCCCAGCCGTTGTTCGGGT
+
;*.8<4'*11)5*FD;29>5B!D;+C0B9@06,A-12(960=?G*CD:,(A0@,<#G<'.83-A%?EH1>?124HD9;6EA33%"D/)E/,$0+93/&<%>4,!!E(;CH(=!)7D*:-29$&,3%,**%D88*31"'8DGA3-='57,>E7!%5;=:;6?#/+;(?FF3=F6H:905!*4-974A@B;<0)$;6>-?=%:92*0344!F),?HF+:3
@r9564
GATGGGGCAGTCAGGCGCTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGTCTGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTANCCTGTTTTTTCTCATGTCCAGGCAGGGATGT
+
ABH)6E#CE;2"7EH?!'B#*!9B#8E3**)12%5(3%?<)A3"F,/9@D(*E%A%F%"*</8'./$('CA19'(F36:"5!H9BF"GA'/#?/8B79<-E9@,/C2$D*$G*<F0;-!:!AAG0"'&#E&7C*4@+!=-<>#/G*D-.0+33AEA6*+"A=):%:>=:DEH30!)A?-E:C;E3DH)"-G.H9A2F&?<*@!*9G+%+0@C6@C.F""C<
@r9565
TGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCC
+
6&)G.8"?$.:$A%&,3E).;119",@1?)'C.&=/0"?*29?+0
@r9566
NNNAGAGNTGANNCTTTNNGNNNNAANNAAGTTGTNTNANGNNNAAACANNGANNNTNNNNAAGNNAAGNNTAGATNNNNTNNNNNTNCA
+
"#!!$$$""##"$!$$"!!""!"$#"!"#"$!$##!"$!#$"!""$!!$!"!$##!$""$"!#$!!!!""!"$#"!!""!"!$!""$$##
@r9567
CGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGA
+
>!+B=.5C2/&*(/HE)B0-,D1=&?&7#3<BFA;462-547)(35C#;:B,)/GD9?%7C1(!:E&>7
@r9568
ATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACNGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACT
+
4<<;!1=9<G%G520#$6C8/>;ED?8#=<*=::@9AE!16'!58@'7/':D38B5C&:,)**59-'E,1EF7"!#&#6,90.%25D#DE=702.$=@A>;9)@?6E$/?"=)+?&,7'#?">66#,+/4D&GHA@7"#4A1G/6@$FH-GF!.<''**D;CA"H<E>=H>582&)$,ED-*&;(&2DB6G1E7!+3?='<D%;
@r9569
AGCNACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTC
+
'#)#*+(*""&(&)+#+"+&&!#!#$*'%$+*$!)#*+)(&*%"#))%%+)+#$)%(#)&**($+&%+%#&%)(("(+'$'"+&!+
@r9570
ATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCNGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAG
+
&98;?98"-<G=C&<D"B4(030!;A..#+91+E=:1*26A/G+D$3!E1,487,&$'=D+!8!+B18GE-H3/4!>!H@:+!.00
@r9571
AAATCCTGAATAGATTTAAGANGGTTATGTTNAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAATAACATTTCAGGGCGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCAC
+
6,FH-+:.$><2,*2="@1A5:0>7!.C269&,B0F/$">'/4-.C)+9E#C&%(?/8+',<9%DE'E($/'<G$/5F,G9A.1E&GH,2'=;03!(.H,7"*3H>@17+6.,>)$4(D#?;H+3G'@&,B:!*'5?#>41(9=0#<@6.6%*38&-@+F86@<>)*/&A21A/B;8:-*$@H20$#:+)7@=-9E?%/:>(
@r9572
AGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATT
+
%H"A%?3+5-9BB7,)288/<DG%1;!=2?*(C@+'-4"G
@r9573
ANCAGTGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTAC
+
#"***"*)(+)&%%+)$!*'+!&#''+"'+$$+(%&!&*'
@r9574
GCCAACGGCAGCNCCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTG
+
=?%%:0=7!6#<25G/;8C=<("8H?B.@!A$25#.00H8E@@0%0(&-F2A
@r9575
NCGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCG
+
04'5'/?48HC?>%D="8**?!0-/F,<<(.G/>.;A*&:3E8C%/+2290?3)F=)C%#&@3A,$&.D'1$,9H98!E6H::8A'5-1&.H@>2DB(A;!*.'0%<DC4@(8!0%
@r9576
CATTACCTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCA
+
.-.%3#E(%?GEH9##E0'350>2A(CF1C2G91B=/6>E9"558218.&E)%8B.$B72&)/'27%-E)/F/,+)D,E8@>E&6!HF/1$<+%="=-
@r9577
CGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGC
+
03<(12##,ECG-399F40';>-'.A=52:&$/<8B;&E).#>%-)4007'2%H+)H>10(4/2E1'>3$H=DG0,>;8)0;AB)C>
@r9578
NANTATTGCTACACCACTGCGTACATGGAGTAAGTCGCTTAAT
+
#5<1!A/*BG+-:4.C)7CD7@&4@/<#/E<?G*9!?9740%F
@r9579
TTATCGAGNCANCCGANATGGTTATNTGTATGTTTTTTATATGAAT
+
%%)***##$#)"'"&$!#+*'"%'()!(&"&$'#&)!&)%$%#*#+
@r9580
GNCTGNCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTGGGTNCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCNCACACATGTCGCGGTGGTTACGTCCGTCACNTTCCCGC
+
!!##)"$$+'#&)*+))%'!$!*$!+!*!*+%!')*((%!)("!"#%%)**+&)#)(&#*''+$#%&$$''+$'"&+*'("#"*#"%!#*!(+(()*+*&)""')%))(+#"(%++##+#)"%!*$#%+'&*#)*()%(")(*'&&"**'(($!'*)'"')+!
@r9581
GAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTG
+
*76;"6/E6(?H%.D<E1@&".&G?7E(&/',8/75AD"!F>##)40E'(=0>0FE9GB5BB(E+?0'*(!%C?C:55G$0'=7E
@r9582
GCGATAGGTCCAGGTGCAGGTGTTGGCCCATGATACGTCC
+
<41,+3"-5.<$H>=F6:G(/28EE'*?.2%!@FGD;:>-
@r9583
TATNANNGCGNGCCGTGGATNNTGNGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCNTGGTCGATTTCAATTTCTA
+
$!*##"#()$'*''(")#")%"%*+*'%(+)))!'*$#'*&+"&&&'$'++%)**#)'()'+%'""*!$#$)(''%($&+('!$)!##!++$(#*#)#*%$*''*'"#!
@r9584
CGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACC
+
A."8!>-'=5B2410<E).%19(-F7C9?#9&-$;56=@9@!4@9F%3*H'8?F()>5:-C<83<<?6=G;)#H2;4&>F21:05=49=78*'(-C'2791;5!1%1;>?E<
@r9585
NANNNGTAANGTGNNANCATGTGTGTTNTTTCGCAGGTCTTTGAGTTTCTGTTGGTACTNTGCCTTGNT
+
!%("%)*!&(*!&$'""$"!!'"%(%$%+#*%'(+'$!&+$(+'(%")(()+&#%)($)%+"&"+*#$!
@r9586
NNAAAGGCGAGCATTNTNNNAGCNTNCCNAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGC
+
"))(&%'("&*')%'"%*&!*$###$%$$')'+)'%!+!*'!%%%"''+!!''(%%%$%+"'$'$%%*%&
@r9587
CAGCGANNGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGG
+
&%%%)(%+#+!"'+#+(#%*'*&&$%!"#')++")*#"#%%$')*'%!"'('!(!!"))$)"'!++)
@r9588
TTTACAGCNGCAGCGATAAGGTGGATGGCAACCCCTACAG
+
0!.FE*4C=AF:.+"+<GF%/.-#:"HF;1<"3->?*;77
@r9589
NATNCTCNNNNNNGANNNNNNNANNNNCANGNTACNCNNGNNNANNANNNNCNTGGGNGGTNNNNAGNTNTANNTNNANCNNNTNNNNNNACAGNNNATTCTATANANGGNNNGCNNNTNTANNCNANANTCNCTCANNNT
+
$#$"!!"!"$"#!#$#!#$!"!#!#!$#""#!$"#!#!!#""!#!!$!$!"$!$"!$!!##!!#!""!$"#$"!##!"##!#!$$!#"$"$$"#$!!$$##"#$#!$!!$#!!$#!!""$#$"!#!"!!!"$"!#$!!!!!
@r9590
CATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAA
+
9!2!'1:)/#+EC@)3465<!H&#',@4#.D7<A(=$:3,%:?07%G/8#)&(
@r9591
TCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACA
+
8D'$B2<$3.DF!#8C;G$5'@A:4E35-:C;),=BH/D!-D51!1D?D.))A&?HBH
@r9592
ATGAATGAAGCCGTNAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACC
+
03HA.@0D"H<B/2,'D3))#@B,!,C6-F-@%+#A1>B'$;=B<,-,@F,E(A2(&/B"A$.;'4H.B"41<F8C<-!@0.3"D1?.
@r9593
NNTNTTTTNTGGANNNCNNGNNNCNCANACNNGNCCNNNANCNNNNNGATCCCNGCNCNTAGNNNNACNTNNNNGANNTNGTTNGCGCGACNAT
+
!#""!"!$##$!#$!!$!!"#!"!#!!""$!"#"$!!$#"""""!!""$##$#$!!!$!!!!$!!!$#!$$"#$!!#!""##!$""$"$#$!!#
@r9594
TGNGACTNNAGCACTNCNNANANAGTNTGCTCNNNGNNANNAANCCNGCAAANNNGACNANGNTTTTNCNCANNNNNNNCANNCGAAAAGGNANTNTNANNANGANNNC
+
""!$!!!#"!#$#"$"$$"!"$!$###"$!$""!"!!"$!"$$!$$""$#!$#""$""$!#$!$$"#####$#$""!""#"$#""#"!"$$"$"$""!#"!#!"$##"#
@r9595
CCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGA
+
9D:>2($)'?3=?)'8&;.2;.7(.B>E'38&A+@4@'516:*3"2D=?0%#<=85!0A8)FAB
@r9596
TCTTGATGCATCATCGAGATAGCNGTCGTCATAGGACTCAGCGGTGAGTTC
+
+"!$$*'+($"+%'+##")%&!$%)&!$"+)+($*&*+++$#$&%*$#"%#
@r9597
NAGAACCCNCTGGCGACNGATTTCGTTCACTTCGTTCTGGTCACGGTTAG
+
!5-DC5)$.%5B/H9D+.#*C2C13$1-H+="$6B&..%B.(8'<E:8&$
@r9598
CNAACGNGTTGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTACAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTTGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGANCGAGAAACGTNAAATGATATAAATATCTATATATTA
+
(!$#(%"#!'+*""$')&'&'*'#!()%$'''"(#$&&"$&*()%+**$(!"'('+"'%"%""'!*$#!!+"$!+*((+"'&##&$%%%&*)#("#%%("++%%#%!)')!#(%'&*'*++'%+++!(!'$"(#%+&"$#&+"&$($!&+)*#%&%'!'!')#&"(&#%+)')"+''%!!"$#&+('#'!))%)#%$*+"%*#''#!)!#%$"$*''!+"!(#($'#')+)$'%&&+!($+$((""(&+&)*%(+&&$$##$!'!++!""$!#!#+!)&*%%(+!##"&""+&%!)"!#%##!(
@r9599
NTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATNCTATAATCTGGTTTTTGTTTTTT
+
'7(06),#!(:+34.+D)@)E)E;7E/?12B:"'FG=0HF8!@>G;"HBAH@6%?CCF4)<+@8D!38)'"5"9(,FE*!8%*>51<%"$?,"#?3%H(3!<(EE+'(BD#>?*FFE0BG!9
@r9600
NGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATC
+
+%!($"%*$"+!#)$$!'(""&("&*%&##"%*)!&)!("$%%%)+)'+"("(&##((('&&$(*"(&'&*
@r9601
AGCCAACCTGAGTCNGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGAGTCTTGACCCTGCCAGCGCCGTCGGTGTCGCATTCT
+
$2#AF5+D?0('(&C%"D;C/(0:H4H>H/=9:=';+)F8H19(-/.795FH:++16/$"0&<)2.?=8;**57FE@/%/"B)/.9E-'"EA-/#?A0>@30+>!!:B!.&A8HF:
@r9602
CAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAA
+
/)."!#F@"?B@E6;+-6=+#@-'-&5A(@>/&<AD>G>$5-0G%6>?B8DB/
@r9603
CGTNCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAG
+
@HD(:4D&/$+>F=;EC#E?72%CH$HD6B3<9,@D$3F#@#"G=+@!07)&H7.!96D)F32*,H,,@4C>>'/9(F&.1/;4@?.;%D;GH5>>!"<D81F-@"/7
@r9604
GCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGAT
+
D4=939&F'<0/H2;;&6*30F#.GC;$.".(A'A4.&+;<0";#:(<8>.G1=:/".!5"*B=.)D-
@r9605
NNAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCNCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGCCGTTCGCAT
+
(!+$)(&*&$$+'#+(%(%)'*&!&%&(&#$')#*$%)*+)+%!"&'*(%'#$)(&()"'*(%)*!"+'+"(!')!)#"!$*&#&&$)#+$%!&&&'!"+(+$)'"''+%)#)$#%("+!!*+()*+'+'&"%!("#+$"+*))%"#)+*&)!+$(!+)'))+%"'%()+(+&%)'"%
@r9606
AGCTTTCCTGACTGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGNTNTCT
+
)+)'&#&%'&+&'"!!))$$(&+#$'$"$!"+(%("'&##'&**#+*(!$!*%#*$++!#&'#'
@r9607
CGAACATTAAGCGACTTACTCGATGCACGCAATGGTGNAGCAATNATTGCAACTCATTCCCCAGTANTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAG
+
0/964+$D."%41'C'7$9C;?>.@8!!/+A&H!.&$>A!'%FH+&3E,3H;B%12?G16G>*=B$H>)3FB')),#2$$&A'=D*/"2H)!>=!='>?@8'-*25G=GC<G23'#!H
@r9608
NTCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCNCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGCAAAAACCTTCAACTACACGGCTCACCTG
+
&=9-'@9&?$(7/)%9#G8>8C.'0DC!#'#E9?"=04E?*@A:,!'19&?-*G6A/?"=8<'/*FF7/@567A;?!54<&?G&BC4(31B2*E-BH.BB<81%D6'3@5D)>?%/9&+:"A:->0E:H/:;<:H)A!;&G"<3:F'D%)5&@HE-7=%E*?D%F:H2(?"")D<08BG!:*"!;E(;1&./1A8")9&$<$4%F5;!#>B1(:7&F-.9H7:
@r9609
CATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAT
+
F7:@2G%?0/F81>9!4"458*H+8!/:F/#G%)=&2>A(5
@r9610
ACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTC
+
<B"@:&-0@(56+H(A(C#9)1/%0=9;?.%2GH&?E,G.F<+#F;-*<7A3(9$D%F;H#?D.'8-(@D@A)."0>2-249@?2&@F39;A<>++1?,?(+H<
@r9611
NNNGCGACGNNTAGNAACNANGNNGACTGGNGNCTNANGNNCNNTCGTGC
+
!#!!$!"#$##"$"#$#"!#!$#!$!$##$$$"$$####!#"!!$$"!!#
@r9612
CAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGC
+
.8>C$-1-'-A*%)7=A<,5$,.C:%5B@+&6*15ED@';85B((@5(4)(&
@r9613
AGNNNNNGNTTNTCNACNACNNNTNCNAGTTNNGNGGGNCCNTGNTNCNNNTTANCGTNANGGANNNGNANANNNNNACTANGNTCNGNCGCANCNTAANNNGNNAGNGNTNNNGTTNCGTNNNNCGTNNNCNCGNTNNCGNTNNCGCNNTANNNCNNNTNNATNAGNNANGNANTGNCGNTNNGAANNGNNNNNNNNNNAACNGTTNCGGNNNGTNTGCCTNAGTNTCGTGTCTCCCNNGNGNNGCAGTNTTANNGGAGCGANNGCATNNNNNATGGNNTNNANNNNNTNNCTANTNGNAACNGGNGCATNNNNNNNNNTCGNNNNAANGCNCNGCTAATNNGNGNNNAGAGCANN
+
"!""#$$#"$$"$""$#""!!!#!"$!!#"#"$$!""$"##!!!$!!#$$!$!#"$!##"!$$"#!""$"##!"#!$"$"##!""#!$"$$$$!$"""$$!!$!$$$!!"!#"#!""#$$###$!#!"!""$"##!$"!#$!#$##!$"#$$"#!#!##"#!$$""$!#!#"#"!!#"$""!!###"!$"!"!"""#!!!$$!"##"!!$$#!!$$!$$!#"!#"!#"#$$""$!#$$$###$"!"$!#"!$$$###!#!$$"!#$$"$!!$!"$$#!"!"#$$!!$$!$$!""$#$!#"$"$"!"!"$!$"!$!"!$$""!$!"##"#"$!!"!$"##$!#"#!$"!"$#!$$$"!
@r9614
TNCATAGCNNCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTANGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGA
+
*#!'$$&%(%'+'!#'("'(&"$"++*)%+"!+%)(#*##+&%!%)!&)&"#)&#$+*#$)'&*')%&#%$!##(!''%+"'(#%$(%
@r9615
TCNCNNNATCAAANNTANCCAATTTTATTCAATAAGTCAATATCATGCCGTTANTATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTNTTCTTTGTGGCACTGCNCCACCAGAGCGTC
+
%"("#!&"(#%"'$$##(+&(+#+%#$##$&%*'%#'+*#+*''!$!*$($(*%'*+$#&&&#++(&&'*(#'"!%%!')++*"#(+)"+!#$)%%"+"$#(+&)$'$$+&))!$'&)"&&&)%!*$$$()$!#")%+#%!%!#%$*'%"(
@r9616
TTCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGT
+
(+#"&!+&$%'+&*%#!!*#"+'#!(%)'*&("('+###%#!'+"*+*')$'(&**#
@r9617
GTACACCAAGCGATTCATCCCTATATCGANAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGNACTGGAGGCAGGAAGACAAACACAGAGCTCTTAATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTG
+
C9749.A5F)'(9C/?4B-,;@"+!G'AD=6*0-+084C&A4((F0()9AC":17*,1.<561#83-2/)*BH0H-!&""/13;/C1H:6'#30*D8H/"4=.:0=5A:6&1,#7>=!0?B@B)F,E$;)0!A:49),/.8E0A?18-,0=6?C=-061E&:)!H'C.7),$-#)5'3?;;E92(=)A*197GA>G,(<8%G$GG<&H4"(HB-82<
@r9618
ATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGNATCAATATGCAATGCTG
+
D&*8-9?B$.+HHE80,?77!,384"=1!A523@)=?B5*4H.$%"8C,/<.0,=C?048)=:B
@r9619
ACNGCTCNGGGCGTTTCGTCAGAAACTGAGNGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCNCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTC
+
()!&$$)!!#*#)++#'$""&("+"")(*%&)(#'!&*''"'&"&*'("&%"$%%++*#$'%'!#$)$"'&%$$$!(()*!!&("%("*#%'&)'*)&&$*&&%"*%'#(%)$)(#%'""&)$*(%&"("%*$+##(&)"(($&(
@r9620
CAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAG
+
48.F#'G4>=*36@"01G>!=7&71664,6&&5HA+0)A3.F
@r9621
GTNAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTTT
+
#(!*+%+$+**()%)#%*'(%"!$$($+!)*++)+#'+%'(*)**($')#!&)&&)((!*"!!'%"'""%#!!)#)"
@r9622
NNCNTNNNTNNTANANNTNNNNGTCACCANACNGNTNNGNNNNAGNNNNNTANNNAGANTACNCNNNTGNNNTNGTTTNNNNNNNTTGNCCNCANNCATCNANCNNATTNGATATNNCTNCNCNNNNNCTNNNGGNCCNTCNCGNNGGNCGAGNGGTCNANTGNNCTGNNGCNCNGNN
+
!"!#$$!#""""#"!$#!"!!!"!$"!""##$"$#$##$!$"#$"!!!"$$#"!!$$$!!#"$$$!#"$""##"!!#$"#!#!!#""$"$$#!"$#!#""!"!#$$$$!#"!$###""$!$#"#""$!"#!!$"#"######"$!""$!$$#$!""$##$!$$!#$$#"$$"!$$"!!
@r9623
AAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCATAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATACCGNCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTANGAAGCGACGCTGAAAAAGCC
+
24=+-C9>81"HFA%5E3'AED1%,&;:.'H5G5FG#2-FH*'?:8'AC<"34?*0D3BG%>9H2$-D,5,F&;7;?);?'AC"A6<D-A?:D.4?9E%B#B($&*B:,%HB(=8<0.7#'/6&3>+=EA/9>(C;%3)"9$'.8:*):5B6)2"5F30,+/6+*61.A71#%4485<C!D%-25>$19;8*7:/;+B&08:#A$$6>@,H44A3:9=G$8>&G*--DD:C'A&0*<>-61;8985DBF"H6C<54+A##&-,CA8>72'C?H$A#G+&>>F0
@r9624
AAACNTANAATGATATAAATATCAATATATTAAATTAGATT
+
8:9GC652F=B%&;?4=GE:8()B,*<?$2#,&")9D#"1?
@r9625
GGTTCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAANCG
+
*E#./B/BG99!/@"DC4,5(?<5""D--F%D-=G,G1<;(6%>F>"C)@'2B5*2!4:F%*)>
@r9626
AAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATNATCTATGGCNGAATGTATAACTGCTGTAACTCTCTTGGCAACNATCGCCCGCAGACACCTTCACGCTG
+
72=?6->;*21*!442"8:>6F2%=8,B(0'*!"=&26%::'AD9$H#<A7-5GF%<+-#3#E&,-DB9))2;EF+(/0;5;DF<6+#1.H8G7(+;.58'#6*=>!&7F2$HG3!H:=A?!.*7H$/@-&60*=>)GC6A27?57"B9CG17C8FC4DH?&73H1=38"
@r9627
CAGTTGCTTGCCAGTGCCGCGTCCCGGCGTCTGGTCACGCAGACCGCCCGAACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGNAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCNACCCGCCAGATGTATGC
+
GC'/'$H-"HE!$1*'?C5%H+552<H<1#@1E7,@5(>'+C7(@=6#!&*BF%(D/2H&=E?(0(*.GH=2C58!''4F$27@C82C9G%E$4*'*5)$9A1/=,6%3@/E99>1>H0:9+3>9)-158<'A$1>61;-G.E7&@/$<<(H)<9G(96@5B"$$62##5>2?);9++/7!'@=;)(2/D+EA+=-$.>2:;D8/?G2%,DEAA;);/:+40$+94,</31!%2%(
@r9628
TTGATTTTTATCAATAGTCGTAGTCATACGNATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAAC
+
-/-F@15E-92(+C*4=+7$;EF,>27<,#A%2F$.#4<CB%4D=18,.?";C<>44DD@'#5<3#<68%>&8+B(%
@r9629
ATAGTAATATCTTTTATGTTCATGGATATTNGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGAT
+
&2*2=(0:8.!F?D"&%B"CC*#-D#H7A<C*G0C8?(%@-",'2$4&B%DH;)(4=E8,%6,F4)/3++E,&%.('-D%2'F@0.!*<!&-,@9).F+.
@r9630
TAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGNTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCT
+
H6=B0E>@;4&91E31,;97A'8;"G:.&'*<.4;3@!!=9,:&/$&H;5(-14?>#D984:!:F6$&7$%'2C-#;"@=CF-G
@r9631
CTTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGGGCTGATG
+
*$*'&+#$'#&!&(#*#!*#&)&*($"(#$)()')*%&$$!#*")'*+#$!*+%)!+"&*&
@r9632
TTTTCTGGNTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTCAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGTTTTCT
+
GH66<D3H"7(<<@.=%#3'(F/63.&/+?B6+./0%30B<H-HA,:=HB3$G><!3&0<G@81#7:!G?1":5#'.2?3<'03487@;(ACA(BH+.3!6F2.;E=6>547<,DA?*!%'()F&1;!-G88"
@r9633
CTNCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCANCGACATTCTTCCTCGGTACATNATCNCCTTTGGCGTTTCCGGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCC
+
4A"FC*/3G&5A&>'=%,-%D7+!1'&-/?;0"@?+.ED2;@@EA=241!>52/<0"8%E%+,%D"'H<-->2<AH7(&"6E:$E#0@>%;16##21-G1(;,C+FB$"@09D4;?0?,@'C64)%>&0)0(3@H?H>F":H:.0--3A5/,?$8(A?B&6G<H)!,0376--40E6H,<C',D1#0#$4/:F:;+#@8!-C8$-328C@E/2=&!?E=$=7%-C/?&!*C+7'C7"EC6@7*+D+
@r9634
CTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCG
+
/,@#(17<!3F9B,D=:,)+=A"1>G:?:H;4-'?/)&.*.=G>>0G&GG8/0B2#D:5",5D;C,3.(=<E/;1@;.>2($@E)/;/:"%870B
@r9635
CCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACNGCATTTGGTGAAGGGAACGTAGTTTTAATCTGT
+
:D=7")"D=)25651%<%1*-#!-7)%8<E"$2F+?9GE94)%%@'-9%G<&=(//328>#*9C;D=2<.B'>652*
@r9636
GTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGA
+
<.'>8=+7E@+/*=#'=G.(,&4;<1&+-15?C?1,>E(#"&)3"2#=>,G;BB:0+D(9E64:>-'B$<?A1(81C5'8E269B2:@0(')AC&@1=0+-#!$>E/5.&6.0*G-+E62(:&?,E%:;57&&4H;3(-A3=/"!4/*.A<585'BGA/?(#5=FG!;2G9-@859-(?FB#.H3,/9D8@#8G9G1/.81B+,.?H#E2&EDCH&(E$BEC0&$=05%0F.'"<FB@-'!D3(9>&8C8A*3:)24
@r9637
NCTGTNNCGNGAGGNTAGNGGNCAACANGTCATGTTTTTCTGGCATCTTCATG
+
!*'%)#$$($(&)&"#"*!'%#+#'$$!$*$"*()#&!+!&(%$(%%*&!*(*
@r9638
NACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGNGAAGCCCTTCTGCGCCCACGCTGAAATCCACGGTCTGC
+
!6:C''B9:H$@=1%=-7&E.1.**8&392*886H=*<:8'#>8:AH;<C)9@54F1?$62>AG;&0&),F6::)36#!2'<3C?A2A$1/F*54D$FB?=?3',&4$(2,1F'3A7C*-A85.)<>%2238)=>*2A),47#2=/5D.:#=6G=2$A504DC5)B+<25&(?;==1?BC?4*:&F<H/?60@$*'2&96=E2.*>
@r9639
GCCGGAGANNNAGNNANTNTGGCTGCCCTGACNGTCCGCTTTCGATAAATAAGCAATACCCTGTGTGCTGGTNCCTTTAACTGTGGATAAACTTCCTGTAATGGTTNCTGTTCCATGCTGACTCCAGCGAGAACTGTGCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGACCNGCTCAGACTGTGAGCATGAGCC
+
!&%%('(%%#&&('#'$&&+'%#%(!"!''**"!#'%&)$''%&*+*'$&"$$&(&'*+*!**(&$%$+&&!$)+##$*%!%!+")&!%##"'#$&##&!#)&&&*''#&"+*!%$+"%##!(%!&'$"#%)(%##&#*")"*"*#&$(!"!")"$"%$%#!*)&#!(&)+!&%(+!'&)""$$$%!"!()+!+$"+"+'+&!"'%)))##
@r9640
GGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGG
+
,19H6;/>?F5;/>C/,-><%22G&?%74.G')AH$4C;H&>/
@r9641
CTTGANAGTCATATCATCTGAATCAAATATTNCTGATGTATCGNTATCGGTAATTCTTA
+
*$+)"$)(+##'*+%&+"(!"'")'(&'))+*)!#*)")!*"&!+!(#%#("'!&&"+!
@r9642
GAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATG
+
+*))%'#&$!*$*"('+)")*!)$)#&'(&"+!(!'"**!+")")"("*&#%++$%"'$(!((('
@r9643
NAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGA
+
(H#=-0#;'79C8"F'E2;7*C@,!,A5'0.>5(B93<D.
@r9644
GTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTG
+
*/!.CH@58(?./7,"0/9#F-#<25/+-#<CH4)9H*?AG<+1-;8(>2/CE;$*0-A9+.<<&13;2!F%*@)'34'!D:;7#H69H0::++3H5&0"E+>3%3&55>!,D?(&<G9D5B.%*
@r9645
NATCGNTCCGGAAANAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAG
+
"&"'&!'*(#()&)"$'!+*'%'#"$#$#%+'$#&*&)*"*+(&%%'!+"%""!'"%'*&*)+&($+&(+%+&(*%)'$(%**+&(&+"%!'**%%#!($*#%"&(++!$+!+()#&!%&
@r9646
NCAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCNCCTGCGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGNGAA
+
#$18C76,F39<:/-(/E>'9;GC<"#$"8%=6%G<-+>=)5/8")A(A<.+DF:.:,2>@5:2$)->>56<54+'.B/-G)@5-8:!D049:'E>$%<2E#HEA@6F"&G75A-&,,1&GF4)"?,D.?'A3):4&6AG2C4,!AHC9H/D5"$?2"D',?!@A+&"1%DH(4G#/F>E(54E?#9/;):=C)+
@r9647
AGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCTCGTCA
+
B:A(=AGD92-82(-;D75G?#!A2#3/.=($=F&5*>22"CAAB)3&7!(,!;A+H83$G%%)<"?>!F@5)A.3B!0B8.@*.&&('+:#@A*8;5<-'2A/#(='$D"!A<,%B?,FC(FB04;(8+@<@"=#11E')'C&)*&C&07!!5(9AG985-1!%4%!*.)<,EB;C33,6,;3F%(6!<:AE/0=3:+<1(+=0=C3?G4&#;9?6"H3=+#
@r9648
ANGTANATCAAAGCGCGANCAACNCCATTCATGCAGGCCGAAAGATTT
+
!#+$%'&&)#!%%(&'*%%+%#'#!'$$)$)"&("#&%++&'+)!$&(
@r9649
GACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTNAGGGTCATCAAAAACACCACGTATCACCGCACCTGNCTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATG
+
D,4F4!E#-<DE85..'C:C)>-9#G?1*#)$6H92;6B:3*1%3%,;#?!#/A=7#9(C(ED!D)D/:,3(DC0D09:@&(%;F/<&8>)0&74/0;G(B%(41.9GB:5+,$=4)*4+G;@+*74(FE!B-BA$
@r9650
TCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCG
+
CB+?+8#((<8:)?FHB3@E(:CA%@,)F6C7&.04?,DCH0E*G.+26-6=G8.2:B2+$0D9#>$C76+2AC3&(:8$&(82,=06<*#4.-4,6:@D*&9:F4.?.'C/6+*<8F'E4-0
@r9651
TCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCA
+
:H<!<0-4!4G+G+E,+.65#.>H!1*-!:8&HF";;8@AE1).-@1,&=C%7(%*/%F/E
@r9652
NNAANACTNNGTCCCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTNATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTGTACAACCGCTCAGGC
+
&!)*#))%(#("!)+("")#)%$#(#$(&)(&#&"&+#')'%)#$%#('')$"('("')!(!''$'%!!++'$"+($$)(!+&$+%!**&$+$&'!!(+'$+'*%&')$*)&)!%#%&!#%''+(*'&*"*#+!"$&'!#$*)!)))")%%$#!"''*%$
@r9653
NAAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCG
+
'$.D)$8@2)?'=@<@"@1%-)=8.!6"$G=52;%*GAD5H!0+,<;?(@@363A>1'(CD<&%<13
@r9654
GGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCC
+
+"!'%!+('($&&""*##(%()'#+!+!)*+*('%(#"*&%*#!)($#')+'*$"%+!!
@r9655
AGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAANCATCGCCGCACAGATG
+
,5AH2660:&A/3,8%D&E;<?&8#2(9F@A?:9FHF6H?08%*>DBC="$-!%7E2<?F=>&/&"$/780'58%B#>)$=D:#:24',+(6%>,4;6*7
@r9656
NNGNNNCGCTNCTCAAAGCGCCANNGGCTGATCACCTCCTGCTCCGGATCGG
+
("'!#"%))$#)*!"%'$%#&)$%$+'&%(#(&)(($'#&($*"#"')#%")
@r9657
CCAGACTCTTGTNATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTA
+
>7E.(-0*$=2E%HE>$>,GH,A"G$/05?/3<'5&&B(5$52E"<:1G/+)*
@r9658
TTTCTTGTTGGTTGCTGCACCANCCTCTTCCTGCAGGCTCGACAGNAG
+
@<0C*F,B$<8+?A@D7G.3B:2)$H?4)G8C-:F@&=&H+,G))B)&
@r9659
GCCGCCNGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAATATTTTTNTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGGGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTGCTTTCGCGGTATCCGTACCGATTCCGGTAAGGTAAACCCCGTTTTTGTTTCGCNTACGTGGCATGCTGGCCACCNGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACANTGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCANCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGNTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATNAGCCAGCTTTCCTCACCCGGCCCC
+
%&+!)&!$!(%+!#'$!+'!+*+&%#("'()(#%*&(+'%'#+')!()*)#*(#*$*"#%'*'%$+")"!&($"%'"$&$+'&&+#((**#%#&*#*!$)#%%!$("#*&!*'''!(""#&$&'&!%)&*'$)('""'+"%%%!$$*!'!#$&%+%+%')()*)*"*#!&%"")#!!((!)%%*('(#&%!!)"*'(&!%&("!+#%#++%+($'"''$&(#)'#"$%"&&&*#!"+&(&&'#"%#"%#$'$(&"'$$%#'$+#!''!$!%+*$+'+&%'$)+&)'$+%$+!$)#+'"&"'+)&&*)!*#$(+(')+&*($*()$*(+#*#("**!))%#"'#$*$!())++#+%)*$"%''+()&''$(!$*%)'(!$(++"!%%!**%)$)!+"+%#(*($&*''#&+$)*)'#!"#%$*+&!"*#)#*$+'$%"+')')"$$$&+%(()+%**)(&#'*)"&'#+)(#"!'#&$'+')'!&%+&*#&"$*&(%%**++#'+%"$#+$+)%)'")#+#)'#"*+$!$!%"#"*'$($'"$!')""+*#
@r9660
CGGTGNCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGTACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGNAATCAAAGGCGCGGACACGTTCAT
+
)<($B=@5?7;D->&7<;/-,A@:C/CA38H2(30=3BA$)AC$%4/.>54:G5&74AAG4$<0%#(<$+<0%C"-#F#+DABA"2?/(4?78/CB<>#+'2#15DG:;2G8>0189>A;",)GHC3)68+:;A@'(?70':?&E<'!FA5B!0<<?3?,=:6!A<A/()10@'B'$BGD&2F6F,G<%8;""A+.E(*.$923(.2!>)G*15=;(G?:,'#A93*#&+5G9CC2H+!*33#A-=77+%:-;.$"E<
@r9661
ACTGACCCGTCGAGCTTAATATTCTATATTGTTGTTCTTTATGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAG
+
;$!-36F!2@*%.>)9@FEB0@3(/5+$1++@!6:H%>9;%3;!#>&:<#+G>=D#3"/*A,38!4<#C5&H@4;:!&?<#49E0B*)+A4#F:,#B)6.9<H,8;F
@r9662
CCTNGCAANCTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCG
+
A+$)-DF/,1&1669(!$%A:C9(C!+&%.&>1.EF*(G!61/6'D
@r9663
CCNCGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCNCAAAGCCAGCCGGAATATCTGGCNGTGCAATATC
+
"&"::E55)=5<CF#1753<57%@$(.20F(F&63(<E:&!5E<31-4.E,#844C18<7:2B,>7&;A.&."-2#
@r9664
CCNCTGCCAGGGACGAAANTGCAATGCGGAATACCTCAGTGGNGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGCACTCTGGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGNCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCNCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAA
+
$*&+&!(&''(%*)*#'#$**"!!&'$!"*'(#)!#(%"!)$"'!$!'$*%**'#"""''+!*(%)*(#(!#&!+("'(*$%*!!*+**"!#(%&!'+%)*+"'%!+*$+*$'%'*'+')(%!!&%!)+*"#&)+$"!!#&*"!'%#"(#*''+%%!(*(&$*!"+$%+)&#"'%*(''$(*)!"*($(''!'$++%!!#%""*!(+#!"&'*)(!(#'($(+!+!#"+$'&&%+"'!
@r9665
TCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATG
+
H%H14E+'A79=30#C(B=#F</EF0E=0FC<"2.=-#&6C5"
@r9666
NTAAACNATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACNAGCGATCGAAAATATCCCTTTGGGNTNCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCA
+
$'!+)$"'+%"&*!$''++)!*'"#*!'"**)+(%(#!!()"$"&$!(+*()&!+!'&*)"$"$)#&''%+$+%&!$"%$)$!!#$$))"$&'#)$+$!'%'*%"#$'!!#"*"&%!(&#&#()'!'+'*%'!#*("'&*+&%*%')&"$(&'$&()'$!*$!"+&(%!)$)($&()*('%))"*"((
@r9667
ANTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGCCCGCGGCTAAAATGGCACG
+
!%+C(367#+1..)-&6%,!*#?$=(%A$C)C'-*0?0/&%#E93,*:-@B;=GC,?<?<30>#;%.=@"4HG)4/3-4
@r9668
GATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTG
+
9;>37)00.B"A@;/4B2G+*@!#>5>.D"4C.,<=:*)9?!@*G%AB!;/5GF()@>G><6G0@.0:F
@r9669
AATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCG
+
;<D89?A!?:&*C5;+//)15"7!E-=<A:A+3G!'@7%"G3C.+#F9+F&H)(<-?C1FF-/6(??$*17
@r9670
TTTCCGCACGAGANACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATC
+
,>5#>,#4.<*F!H8A0;<C5"93C(D6!B7%/*1,?58/+#E9'-9&7<H'$%H*:B6>&=+2BA%*..)D;A,:38F=!68B&8?$&37':>D?*H.D!40$/"(9E%7!&A<CF0A3*,5+6
@r9671
GAANANNNNAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGAT
+
)(&#*))"+(("#*'$!!$""&"*)"&'%!$!!(%(+('$"$''%#&"(%
@r9672
AGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTCACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACNTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACNCTTATGAAAAATGGCTA
+
B>D'!6/E/>'?8*,03C4')C.?89=6EC'5F*'1.=3C#%;:DHA"B5E.;B+H=D/A&9#8:A<55'%3.F@!6*+95@C:;?B:<54;".=A$..>,,AE%:"@02.,3EG%;;"+)1F#9-?=#8@6/A,;/9$;C=B",68-FH<<<B%7<E#3@4?4D',D(9%<BC2(D*#)9+&CDCC#.;F$42%EF+39*C*C."2;;)"%>
@r9673
AGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGGT
+
-'+1(5F!36!@;$4916;;5;B(=71=E)F&$//'3G:&'!*(*"A
@r9674
GTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGNTTCGCAGGCT
+
B521E/4G:2?.!!BA?(A@:-*0%)"&C4!(,(3EE001D7#.%%?1+CE2#$/#(,,9?'4/C0%+
@r9675
TCGCTCAGTGTTGATCTGANTAACTGGGCTGACGCCGCCTTGCCCTCGTCT
+
+-?0;A4%?3=7E'!2=,/3E*%B;E!H8//1G-A#:%(1#D)B*?/()A8
@r9676
TTAATCAGCATCTCCTGCGCGGTATCAGGACGANCAATANCCAGCACCGCATCCCACATGGTTTTGAATGCCCGCGCAGTCCTGTCTGCCCAGNTCTCCAGCGTGCCCA
+
5*9($//:3H-.);05EF.(A*/"B/&49A@-C!$=E4)*/%E99/<&D!'&BH1./+D%@3-;$D?",H4>3"CB8C!(8$"4#<)-6#CB%-0D@6(A8/)$!@F?.
@r9677
GCGATACCTGGCNGGCGGAGCTGCATATCGAAGTTTTCCAGCCTGCTCAGGTGACGGATTCAGAGCTGGATGNG
+
#0,9B$)D")6@+B>3E<=9B@8?:3E68&*27,3+?1+0)F$.A2++:3<2DC'.B/%58=>7*<:2:%8+6%
@r9678
TACTACTAATTTTTAGATGGAAAACGTATATAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGC
+
/"'(;3+D(=GH'0(:=))?<?:282(<18E<$*4+'/&>(DF0H.-BC9,07$0F>2!2FC,4*/2;5C
@r9679
ATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGNCCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGG
+
=+5@-"H$:F@7%>&E-48!<$:44FE@78><87@-B*)>523/2D$1C4#0'1,>%%H,16))-*EF+)>.97/+(EA61*')+>/42#%,4=
@r9680
ACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGCAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTC
+
4!3BCDCB!=6A.4FD+E)50E,>;DG>;FC->FA9?A/-:+2B';5D$/$E<%?<+91?.86C1>!&3G5$?;6.!@7;)/$)+&88,"FF(@BD5<
@r9681
GGACGTGGCGAAAATCCCNATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGCTGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGT
+
%(('&$#*#)++"*%)!""$!')(*$+$%*+$)(%"&%%')%$)!(*+!"+*!+((%%&+!&!'%)+(%"')())'"!)$&&)$#")#)*''!!%+#!'#%%&"''"#&'"!")""!'$$$+*'+$#%'$##&"%&!#$'!$+'%!!('#"!')$'+"(+!#'&
@r9682
AGGTATTCCGCATTGCACTTTCGGCCCTGGCAGTGGTCGTCTCTT
+
1)'1?:+/66A>")C8@F#8%>,!!@@/>("GAA@&&)8GC10=E
@r9683
AGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAA
+
/:2+#)0$.*<G9A*0<</04,,G8?G@)?HHF#(%:E0GG-/68:1ED21:*>:):%53F%+"G&,+*%70:4('G&=7)%6091$>?F/(5)3A=92H>%"GG>'FE?0"<#?>)E,%8.$$H1(&-*A6>D>&3E<6E@2,!35&HF=53%#2HG"?)6H+A7HG;;!+@B%E7A2027@C<.?>$'"494-%F%@#G44$:81F4A48:-3:+(%?",HC/(29$,/B*B#F9&=H/'"6517H1-'/5%8B:9+6-G"+/0/#19'D(FC.<A<;,(=)0G/>(H#;;447,+#.
@r9684
CCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTGGGCCCCGNCGACTCTGGGAACAATATGNATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCNGACGTGCTGACGTCCCG
+
A55:B8+C&('6H06)F*4/5%*0AF3B631)*;9,F!&+8D="C<C"FAE*61#"%'!%=(28:D:@4#G!0:,.?<*;.5'-8/G9(#=0*@@3>%5,E:$6H%G7H)C--*B'5;2@83,F'8-$(8-,.;?7E4)":G'
@r9685
CTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTT
+
*B+.?*@";)*7"39H<'+.,+<-17B4G*:03#(81)';$25#AF#.<@43.%32-!2E%3?>7)+'/;H!F;(3%GA-5
@r9686
NCTACACGNCGNNGATGGCATACGTGCCGTCGTCGTTCAC
+
''"#&&$*#(#&%*'$)&$+(""(+&+#%$(#(($+)")&
@r9687
NATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGAT
+
&@!/G'#:=2(+'<"E>5'D1.;?B%!-(>.*#E)<+!E";.:"B*
@r9688
TCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCT
+
6/5H2;*<?%:'5*4*F,.'9$A<>$#>))4-DCA2F@%,3)!A9?E3)0373)!,)%:
@r9689
CTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTTTTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATANTACATAACAATCCTCGCACTCGCGGGGATTT
+
!3,;.?,33/28@HE-<B:>1E&C*7.9?F.6'#3.6'-$FH?7?9$8/)-)':+6:1!%2/*2?8H81&A,)87#(#B&D8)"2GH(.>)&("=34#<1$"(3D)E><?:/9/:#,)D/C>C*?+H>E=;$'%8('<!*H1%;>H&=DBA3*#01$F*CD0>*%,#6%)!,*F>E"?B1G%-H;G@'272"-)?F&-0EHA-2C)(C;0*-G,&6EH$>&05<6
@r9690
GNCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCC
+
(!@+EE%F,';;$>E--2D!4'*0E7=<H7&5='C6&EDEC91':@5!"G++4:@?/,GH!E?6:C!4/E0A2$#"$;-5C$E-AG&?;6,B1$#>,7D3"3%C.-3;A8&+;.C6$%$7*22'!C;
@r9691
TCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGTACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGC
+
1$G@81+!&E*H!(2%3?:3=!02-,9/.G%!6#0#%.D)'5C.<,"#BD#;>D7)9CE,D;/&:H0&9),:-";/.-!D"C@E%3'5FB8-9)8/!*8+";*4@-,$E!G2#.?3F<"7#99E*64;%+6.&,)(/*=0&.D&=7E)!--?$!(;"#16+#)"*<
@r9692
ANCGCCNGCGGNNTCGTACGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCNCTGCGTGAATATCTCCGGTGA
+
'!&$%&()''$)(#$)+*+)*"&$+(*!"*$"*##%'(#$&%!+#"#)&$&''"+!#+#&'*)#"$""(($#+*&(%!+)$
@r9693
ACGAAGGGGNCGGTGGTCAGGTTGTGGTGATTGGTCGCTNATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAAGAAGCAGTAAGGATACCCCGNGCGAAGCGAAG
+
+"*#%""&"*%*%'(*)&#')##"##)#'"*&$%&*)'**#+*"'(&$&)(&'$%(&"%&+*(('($&(+''!(*#'#!#&)'"'$+&(""'&"+*+$*#$!&$")!"&!%('"(*&"%#'%*"#*$%%#+'#&!*&'%**&)
@r9694
TGAGTATTGGTTTATTTGTCGATTATTATCTTCAGGAGAA
+
2=,9CD>9;'A@?'."7A*$>#28)D8)4H;=*>$3G,7H
@r9695
CCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATNAAGCACCTCATTACCCTTGCCACCGCCTCGCCGAACGGGCATTCCCTGTTCCTNCCANTTCTGAATGGTAC
+
?19%4GB#G5:.-E4+.?F0?.5A8(DD;9ACGA"G73.1CA;.::,AC/;),DH9-%D?1?=<<45C:.0!D=D*:&B7C0"9FH9","4%'64>6/47AE'A956%C73
@r9696
CGACAGANGAGTTAGTTGAGTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAAAAATTCCATCCAATTGATTTAATCAATAC
+
?<*'D.0%=;3H/CDA0/8A7G8(A-?*6)#+><D<(?21FBGH$&;?GG1>**=<+2,7FC+A$,B.:E%=?=::"4>.2!;D61D37E>CHE5!0F:5&?9F3G+9*(8@+@-072>DA8?0
@r9697
GTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATAATGCCCGACGGAAATNCCCGC
+
C91.:%:"G4B=;81,*/)3ACH>A(%9+1)*,'H@72EF<2D:7G10(E%8(1+!7:<*B+%2/?86)89
@r9698
GTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATA
+
B5??B<,=BA#8E=%.7C7&.!=:&E5)=E;=<&CEH7),<?,4'=7%D!$!E9;G7,A.%%6>?C-/("<0G=31FF)?--%)9*A5.;.27.!.=A$8H3:<2%8:B;2G4=(DC$()))")(8@1'7@G"H>A?5',=AF7=1/7E==>DA!580AB03,7AF/6C1">%125A'B+6
@r9699
GACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTNTTTATTTCTGAACTCGGTCCGTTACC
+
'28A4)/.#08*E;(4DG3G+@D*3=:-)-)4.1"!(5);B)/*72-3</CG#"9-B57<>EE+#;E9<9C72&
@r9700
CGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGAC
+
A,'0@((95F!)/:C5&8-:C0,H>7:<4"4D(6=14H??D!G@%2"H,<E@6<AH0B?1D2+8F2+!*8@F6D**)<D;?36?>@*"?3":#=&F6;B=?'FBBB<?&7,=,(0,F?02H@0<6>@;+D4;6/;+8D%H,";F:;$4:*&;,/@!1=3>;7#!B07>21+H1D?C5F@/.0D9@%?5&GA0)A2'DA*"6>40>A.&<(C(2G)8E?+.HD+8"%$"0*663H:5&'B;==#5'/6A0>=?$#0-A+C*-4$'
@r9701
GAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATNATGCCGTTAATATGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCNTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGA
+
3H:#+46>1E0+<H9'5$E$5,%83*%798<<A2*80:<&BFD,A(!4)A(4&D6+-6"@B==/"20-.G<2=/"3!AC:H/.53C,#-F.C7HC"/*'/)-*G9"G/:62#-@H5$&;'%)6*998+F:><*30+AC!C9,G8!A;8+'6!1-*&E'>G6;.24GGG(!'#E#$/G(',2C&&*G0#>!@87'-:?3=':3*2<0+D3,(%(BB59(?%"C69D)+)6EH34"G;H9=57:448$C&8-6";$=BE-76D#8<"#C>5G@($@1;A'+/
@r9702
CGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGT
+
?!E'"B?2?'+-")->B'H9&6%;C0F%.)&23<:=?5A)@E>%1;D;4>5
@r9703
CCAGGAGAATAACTTATTTAAAATTAAAAGANTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGAGAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTT
+
B*+;>+D/91@:$H?(/3=(:-;5*H?;?%"/1*)-6>$,93*%;"*8*2H4:<8C2,7&HF+5<$5GB9:/(C54;(C+D.9#'0D>&$(/3;"%B8$%3341//1@2$.5;.C=3D'<A=1A(3,;<0".<>@$$C!'3)6@E!8;A=-?:</&3CEA#?=C5=)=D1D);+515%7CB1,6A$*)>5A1F.(8:7B</F"*;4%<$&)%?3!B(D#:.(BF1
@r9704
CGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCT
+
%;=%"!2(H):$%:5H;07DH)E+A%/1*!F9,7$F137!/#?&<)(7@?;")1?F'D'3A2E%@09=$+D2'ED'.93212+@
@r9705
NTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACTAACTGTTTCAAGG
+
!B&.?@<40:F85@4H6;(9?-AD(2"F*576*@A+>G8GH#>47(9EC69D"$/#7+
@r9706
ATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGT
+
550E>$(+$@:3$38%=7H8%DH+=2);FH<1$$45'GB<7@,6/)81</'<.3?.,2G*66*A4!*7/3+74F&:;175:798-D5.&+..1-/0-?<='?C=.@
@r9707
GNGTNNTTNCNACCAGNNANTNCACAGTACCCAATGATCCCATGCAATGACAGAGTT
+
%#*#(#'*#(&!*%$!*!)$"&(#%'%#+%&$("&!+$$(%+"%%%%'"%(#)'%%)
@r9708
TTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACT
+
+61"'!.C>:&+<#H=9:D$6D.7<;:53)5AH?@--F4-='>AD#,718&E&>B!9<H#-
@r9709
GGTTCGTCCGCGAACGGGCGTTTTATTATAAAACAGTGAGA
+
+51+.5AC&>4?G9(,>05*D23<C7#/F*234@></GF)6
@r9710
CNNTGCNCTCANTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAG
+
(!!!"%!&+$%%'%!"&&'#")"%'&""+)#)!$$)"!%%&%+%"!!$!)"$#(+()*#*!%#+$)*&$$"!+%%#(!$)%*)#"
@r9711
CGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTG
+
?'B)E##7*E-C$6#E12B<=;"537*@<,)&;:7:3+;9D'F2@@*0H&5'$EE8#0'=$7
@r9712
GTCACCCATTGGATTGTTTATTTGTTAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGGAGA
+
+C"HE""/A<GEH!?"D)*F?*#>&C?BA,D,DHBE0"73<"->8-,2?'$$.7&?%!'4(D*'>2.04'3$1)"#0=(8+45G$
@r9713
GCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATNTGAGGCCAAACGGCGT
+
+1"<:G<-F.2BE.!;;D'@-B)1?/B'A#CD>/9)&-/-/2-?1$5AG98).".D)9@>:/?+6??26D-,,-@3C"=4"*>F<*4:"/A
@r9714
TTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAG
+
6F5''4&D58!@)8A.7A=$=C-?4<4<&2&%B!0/!5'7<19AG#&<&"6%8E.9AF*G/$$&780/!!):/!/G41=7;!)6:$A=:+-"!1*EEH).4<B7@GH3B<D/AC@408-D
@r9715
TCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGG
+
7.33@+AG!0=-)2D("?C;?D2.GHC.B37$(5.3!E@!$F?A30-H:'*=>)6+'*0&1$=+C&C0<!5"
@r9716
CTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATC
+
;/"/BF<F90!&C8:4@@F3;;29C1B'G<;CC6G!%EC<+.14=F?E=$)1%";G"AE1=>'-C:-E))*<"B!EG-H'$:#"D+>'A:C*%:#A(C(A!"(*3HHH&2D7/91:+3F=5#
@r9717
GAATGNCGGGAATGGTTTCACCCTGCANTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCG
+
.)D%$11,29$B31G9)7:7&7E5+;/1;'.1-D52DG0?66.<@6?54A5'"/<A%50"<%641'2/0C-"#6?748@=H(G7'G$7,9.-$%1H@=:!39#*4@/1
@r9718
TCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAA
+
C'"@A(H;(5@FG0=B((;2%+@(-553$>3.<6.,,#1A?-$69B(%)F@526%(7C4:0?769+<
@r9719
ATGATAATAANAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCANTTAATTTT
+
193B1'=0)!C9%2B/?%5*A:A@:/'-:96'05$;*=?)'/+0=1H!*(?96&90$=>?#2+</)D59?B;$?*C62?F97(3.?D&<AD.4)5D;DA?#B(E4<4'*D4B!H/!;
@r9720
CCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCNCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGC
+
:E2<C7+?7$,3F4>B6%D!C,<+#&4EB:)$709*!3"2//><>6(#3-90#(*)%/E/:3<C/GA>&?9;=&&'?8*589?>1E4?5**0<=HB?+A<@6+G$;+F$!"06<='"8)0C2<)9=6;?!/G:G8"1$73"?&C)4*2H<5>'5<+GB:7(
@r9721
GNGNCNTNTNNCNNNTANNTCNNCNNNCGCGNTGNTNNNTCAGNNCNNTNANGACTNTCNACAGNATNNCTNNNTNGANCATTGNTCATCTNNN
+
!"!!##"!!""!##"!##"##!!$##"!#$$!"#!""$!!"$$!""!$"#$!""!#!!#"!##"!#!!"#$$!"$$#!"#"$!"!##""""!#!
@r9722
AATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATAC
+
A)/.82H3-,;<-C@7-H>CGH6(!;A'<'43,3H@!F!4EA7>1
@r9723
NGCACGACCGGCACTTGATGATGCNTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGTCGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCA
+
!953/$05$'*F/8$7H"0%30+D2#A4%).HG&".;&>7F(95,90$&!939C*C5=01@%G5*G$H=6G"2H(:#-'35:*AE=:0@-;+"H'7$+F'E#H6C43B,+@:=9(4(@?F3>H$88CA9!H-*$F:/B:0=3633;E19-?10;,@)/3$2<@%=-<A*4<#&#,7GG%4!?/<39@0)A3.4E+A/@-91.0#H(H1=">/>6F61-;C=50
@r9724
GCATGCCAGCACCTCGGTGGTGAAAGNGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTTGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGNGTTTGCTNCGGTTGCAGAAATTACCGTCACCGCCAGTNAATCCNGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAANCGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGC
+
0D'#'EC/BG(HF5'$7'!:>(@@AEG6B0%-6%B#,&-2%=4%86;@D+&#+++=%-7=7)H#3:E8:6G(!!B:(06:C.F58!8+(,!!B65*@0.<@+:6;:H85*H7??=EE3.H"(&,':?+#7@',-)<G7#";1><25-?,G?3HD1!!$@.3G;38G'%21:B/!&#&"0D2=;D,AF>6@E</:E.:C4.?(2:;-+10><,:?"3E679<&(''->F2?43GF,,'@-?013;<+?HC?-D.E9=A%"#1;"6#EA09H/F51D+(&C#";D:F.=/BE>6@?:1B6+4-!/D(8<+;H$"(860$E?>#-"C5!G>BA%$2C+!%E@2!3"E<2DG=9315H+!3F*0.<@56+<)@)F6F"2/1!.'#1'A0=A/$7#@@A+=F85F((9;8@!B.,.E+648$C=G,5"G($97!!&!!>A<)"<-*
@r9725
TGGCNTCNTCNNGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCANCCTGTTTTCTCTCGGTGCCAGTATGGT
+
%"&#!#*#&"#)+&&($*#$''&*!%*$&!")"%)$+#(&(%&&"*#&!$(%'"&$(#!'(%"$"'$&*%)+'&*"$)#!#**&)#')&+*)+!!+#(**#*'!$"''((*#$!((%+#)!$#*$"(!(#!)+!+!&&*&$
@r9726
AACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAG
+
C!7(>446F1/G;<D&:'821@'87!5C19-&0D2DE1;(,/26
@r9727
TCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAANAACATTGATNCCGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCG
+
#'6#&==E!"1*<C5$39"!"D'HB94<D20D);G025(%C'1/%*6"%@7<CB,"B%'CFE9"'74#4&H"E,B,!0-;A=H,G<!*!;F*8@(0F$18?<B)3$7-4E.
@r9728
AGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATT
+
/)<:,?4C))9A6FF!70$+24)HD$$CHCF):B5,&574*@*E0H(G>BB2&/
@r9729
CCGAATCTTTACTTGAACGAATCACCCGTAAATCACGTGACGGATGGAAACGCCTTATCGACATACTTAATC
+
9EFG)@4*"8&(0=&B53H0,@;*3*3==-#*<0>BF4:&3='4-6?E*#@0H4,%1DE148=5'CF!!,E!
@r9730
AAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAA
+
H)/F.>(G39!2)%85=6''-#.-@H6HGBE37:1.'F:?F--!@E0>,2=/:>,<)<%81,;E,<F#)86?1FG4D&*+.9>,5?%.FC"2"E<A2:)4C:&/%-0D92>$0+6(,>),?:?D)/E7@DF4:(=@<!93,G=H3&,?(@D-3;+/3(/&*$2')7B4&
@r9731
ACTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCA
+
#/=25A674,789@:;*'H8(D,E.6-B%,+61;?-@-(#2,3C>-C-7&):/7%@562.1,G+-A%4B!"?F4A0#+(-B@D=+C01;(H7>GF4+$*E4.2G47?9!G:,'@?<1'5592.CH&&;&.
@r9732
GGACTTACTTCTTCTTTTTGACCTACAANACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCAT
+
$!!+#))%'+(')+('!+&(&%(+$#)(+*))+*$!""%+!("%)"')'&&%#""+)""%!!%#$%%(('!("&$"(")(%*+#%'*$)+'*%"$!*%"')'%!!!&#%%++&$%'))"($%!"
@r9733
CGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTA
+
4D&)89'H"1#2*<52$+5/:A/?;>9)=1)&"+%./2<2CH!'&;#B:3
@r9734
AGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCANCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGNCCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAAC
+
G!E8H>&BC08*0'0-+"0/41!F20(/0+&7F22!9.1/,)"862G$:B*B?(+,A0/7<93#,E)A60D7EA)6+"+=5)+@<@F-!10#A@&G7A@-G!386/;3@;.;AA9<9"8518*1+?0))$ED4*7;:=F'B0+?"'<A)0?&G.<;+(8=H6C6&&$)">4G.':9',D=/2;9;#>?.9E;D>B2>G!E1636?;E#
@r9735
NGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATNGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGAGTATCCGTATGACTACGACTATTGATAAAANTCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCTAGCTGCAANCGGAATNCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGANAAATGGGCAAGACGAACGACGGCA
+
"03.6(H02D4.;@>$?3H532&D'5:';//C'9<&E8@0!7-$0C%#8C4(HHDE)4/H"9H799%;@988=<:3C):)>)F(->E3<3*C32(?.77<+<7"*);%,7E,4DE?<)1841D&3/G*%=$8'1<%0'4B7975E?0G;?+'!42!;6$-EA(:-+?1F.;H&E!/,1)3A>;D(.:0D:E'17*DA5-0=6)6;>4F=963,F>)9C68,.@?H:7'G)01)D'%5.D#502B:03#CE*<>&5#7?3/!*39/"0"*,E*@
@r9736
TATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCANTACTACTAATTTTTAGATGGAAAACGTATNTAATAGAGAGTAACTTAAAAGAAAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGG
+
>E.;'BH(>C%?*3?,C!@H:#?!'-G*-D!#;D$A'83'H8/!(C)/7H*7-C$1<E"233/.=1E$>-F'/;1+*5.#BG)G?2(3149,G7<,D76'?",3143$0=GA86/D(%0H1AA3%/)6)GF"&-9C2H,<!2!5F):@0#:9&(-2@50)F#=E63%;6,#E;+BGC1'&=7,8!08"A;947+(0>#E<BB)%<),-F27%!)GD/5+4"$H/31?5)%%#)3-
@r9737
ACAACCGGAATNTTGACCTTGCCTGCAGCAACGCCGTTCACGG
+
@$/??=.-0;)&@(5*D2"4"9D5(<7B%HF,:/H7+G&@32E
@r9738
AAGAAACTGGTTTCCGTCNTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCG
+
1+6+G&'E8=C1+;AF"=#B9.1*/A.?&2,6./84->:6)!%5#*7B:</4/8+H!#A13=G202-8%(B26#-45".B3543/*7$&AG+&H1D=!?)
@r9739
CTCAACACGCAGTTTCCCTACTGTTAGCGGAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTAATGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCT
+
5C)6@2"+=3D$3%'D'G'?%+4*):A$5:%<4B@9!'#41.G&<>E;(0&E<9"G'F/D1.?E6.+8'20@6DC':7D)673,3)>0?H;"/D:*/1#&#/E+(:,"C)<:#A9!H?2/0539(">B8DC+F:5DG(:H75>.!1HB61-60,G=>FH&/.H(?*!2+22F/E-)/#**661A3H-1"5;,!+29;$+6,)7%1AH3&>9@+%?1:8:+AD
@r9740
CATGATNGCCACGGAGGGCATATTAACGGCATGATATTGACTTATTGAAT
+
:C.B*B4B(&$@,)39#4B%>*"++'27$A$C2!G.-"&%,.<;>%;'86
@r9741
CTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAG
+
!$G-E<>3&0#/(3')//<&;>#=B5(5!>GA.A=C?#/9>G8DG8888758).!))<(%==+8:>H:25-&7"9
@r9742
NNNACCGAANTCANGAGTNGNAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACNGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAG
+
"")*))$**''''!"!&)")#&&)+$$+++%&#$$+)%$))#+"'#&()''$#!('%#(#$%((*)$$!(+($!)"%(###%!*)!)&+)%#&&("(%$""*(*&!(*)*+$'&"")()"'!&$*!%(*"%&%*#'$('+'%('#"%##&()'+*)&+)))'%$"+$(!((*'%"
@r9743
AGATGAGNTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTC
+
/30D'2:6@"'=F%/#08/";-5!0*G&"<??%*76BE(2$&1.A/53D9)6)&<??274+=%##$G8G&#,F%8HD=A
@r9744
GCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAANCAACGAAGTCCCTGAAGACGGAAACCNGTTTCTTGTTGTTCGCCATCCTGGGAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAA
+
"84&F$$,63#FD)>2#4F;.D#=D,+AD+A8/2!3"98EH$G?CBC6&0E;$$5#B'FE(?G+!H2F4:6+F&<F>>AB@2BB.+"17H)49+-<3&82*-6?D<@5.>H$4''/+66,-";(-E&%&=&"10E;7E;6%F%#B+=G2(-*%"BHD-@E-7F"&2B#(9G9(2*CB>2G<,G35<759@<36>:&@$(*1*65.F+
@r9745
CTNNATNTCACNTNNCGNANTANGTNNAGNGCNTNGGTGNNAATTNNACCNNGNANCNCGCGANGCNTGNTCNNTNNATCNGATNNNGGNNTNNNNGNGTNTTCNNNTGAGNAANNTNTAANCTAGNN
+
"#$"#!$###!#"$$!$"#"$$"#""#"#$$##"####""#"!"!#!$$##"$#"#"$"!"!###!!$"""$#"#$$$$!$$$###$!"#"!$$!$#$""#!#"""##!"""!$!!"#"##$$"""##
@r9746
GGGAGCAATGGCGATGACGCATCCTCACGATAATATGCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCA
+
-,!D)E(*63#@1(F+#F>D5%A2%;0HD8D<A6=''6*5@9&H1:69:'?.>FE7H5=";CC"8+/1'9:"D3*A9>$97-+<;A&8/)+1=9EBC#1A0$C+2H0D;CG&8))#%?
@r9747
CCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCAGCTTCCATNACAGGAAAC
+
E>.)&+H'#*073HGC*0$H0B:B#F)G!'$8"E>)40DC?G(C6C,H1+23"09+0B&/@%B+&/C*F3"9/90@&5G.(2((52/&D'?6>(ED4./F1%42G4,763A,D=EHF",?.<
@r9748
TGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGNGGCNGATATAATGGCGGTGCGTTTACAAAANCAGTAATCGACGCAACGATGTGCGCCCTTNTNGCCTGG
+
;1H<@5*<2):(?32D6>4)$(!-3:"3(GCF/99"+<E+A8:BE-97'3G=231C:.6F%D:5.("<>5G(+<=B&>'"(#0"*6*8(-6"G2E>"/EG)&G9,G6(0F>C2),!)394CF4G>>?:/GFA>D0H;30>
@r9749
GACGGTCAACCGNAGGCGGTACGCCCTGTCCAAGCCAGAGATGACAA
+
&)0;30&1C=9.G$!G6.7A?E"(=HA>&4)"C=;$4D1H@&53*D,
@r9750
CATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGNCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGA
+
-E.8A5D@>#(C!/AG/E8)@7:07(D#H#C%E3>(?8=*?2#CAB.2F!*4(@*6%>;1#<%*D'".'B(8,3&<.&@+@0B(8-9?"13=.:+3)D4EB=@&/'@
@r9751
TGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACNGCGCATCGCCGAGCAGAAATCGCTGAGAACATCCCACGCCTTACGCTGTGTGGTCAGGGACGCATTACAGGTGATGNGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTTCTGGCCGATGACATACAGCGNCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCC
+
<&-7-*3$#=CA=+?>,-H@+2;1/*8A)&25C)G-=B!=@1$-G:G1?/0+":"C<+*C4)>$1'9&A,=>9H76!$@24D2)DB60*#.=&"42#>+,E/6@<2*'E9H&(4)#A-*H$<!3:F0.3,E>F83HF5AF#+7!0!868&>*,*!%$0271=!(#!F)>+5C-%A61;6?@-H*&1#C<&/.345HE3>#"7"1)$-G<9727=!@1,7&:67$%
@r9752
GGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTCTTGTTTTTTTG
+
%('+$*!"!&'$&*$*"!+%)!$'(""&($)*%&%#()%*"%()%"'
@r9753
TNNNNACAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGC
+
("#%%'+*+*'!++('&#!%%#(*)!&&('&$&$)()$#**#!$+%!**#'(!&#+"+)++&%!(*'"!$!%())#"&!"+$$)'#&'$)'!$)'+"+(%!(('
@r9754
ACNGGCNNGNCGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTNAC
+
&%#%&""#)'%*$%&+*!'*+'*"&'**%'%)($%''%")#()'*%*+!**&)!(*""+!**!!%!(*()!)+((*)
@r9755
CCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCNGCGACGGCG
+
);H*8B=A.32='1:>.<3/!A=53697@@8DH&;C)3$5@H%H7G*0&H,(H:44$%:+
@r9756
NNNNNTANCNACNCNAAGCANACNGNNCNNNNNNCGTNNNATGCNNNANANANTTNNANCGTNNNGNNTNNNNNNNNNNAGCANNGGGAGTTNANNNNANAANAGTNNTNNNACNNTNCNAACANNNGGNCCACNNTNNTNNNTN
+
#"!"##$"$!"#$$"""!$##!$#"""$$"#$##$$$"""##"$#!!""!!#"#!!#"$##!!"!$##$!#"!#!!!!"""$$!$##$"!$$"!#!#!!!$"""!$!"###!#$#""$!!"$$#"##!#!"$"""!"!!"!$"$#
@r9757
ATAGATACAACTCACTAAACATAGCAATTCAGCTCTCTCACCTAC
+
4A@)H$,<2588G?=#,A=B?#$621:&!4%+/.7..-.H'!F15
@r9758
GNNTAANCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAANTGGATTGACCCGAACAACGGCTGNGAGACGGCGACAGAGCTTGTTG
+
*!"!!"%(+('(!)&&*&##(($**&)$!("$"''+('#!#+"'')&'!')(!*+(&)&%*#"!!'&))*$!&+(%&)$+#))&$&)'!&
@r9759
NAACAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAANGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCNANCGCGGCATAACATG
+
#%&*+$""+"''*((!%'$$)'$"%*&)!"')'#&'!#(%'%%+'#"%'#)'*"$'$%)')%#&&$#"'*+*($"*+*+$&!!*+)$')(%)&#*!&"(!#$)"$$&'##($)$)%"*)#%%(($#'*%'#*&!))!)(!%")*+++"(%$!(+#'&'+()*+&!%))$'$$+*'+*))&('""#+*
@r9760
GNGCTGGCGAACAGGGGGATGATGCGTGGCACNAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTNACAACG
+
$$*)')&+)'"!%$&$"+$+&&!+*&"#+*+("$&""'('"!"$'!%!%+'+'(&&+(+$!''!()*%)%&*&'(
@r9761
CCACCTCAACCGGATCGAAGGCTTNACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATG
+
1?12(*1F)"A,44)".6&-:H+01>'.E&%7HF%-A-FA1G,5:3&A&;5,31+;@9A/C,%(=&B$GA;20/2<E"@=A.=0(#F@5)<$0@9$!4.!4"0"B7:HGA.-&C@6*BG@A0
@r9762
TTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGAT
+
E#D305673G7.<8,/.0H,"E%=/'2+;D(*H67C@G#84+>(.<9=9'%"@%,0#!*9)E2).+#)E%&-.
@r9763
GGCANTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCNCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCA
+
=3H(6E59+2+=:AA*-(;+=<'15-512'6#&/35%"&&/5H(>;@D*F687C"$,C>$94@('>A)-?D=GCC3&(?0.!<&B2#GD$+-A*(/7#1&<2'H,=B35B24*?<,:.E01;
@r9764
ANAACAGTAATCGACGCAACGATGTGNGCCATTATCGCCTGG
+
7'F"552D3)'$+H?=9"<,8;1)BHB*5+1!#!.>+33!50
@r9765
GATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGAT
+
4FH.+21<0/DE'6C?)>&D4,A1B,25G9,@3+!99(%GE$A@!:)4G/+EA,$#H+H-?G)7%,?<,G#)1=F&#'.7:E,F1"0>2"0%+$;H
@r9766
CAGGACAACGTATTCGATGTGTTANCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCC
+
E>=>+AE0&'+'%DF*%+/1.$C"$-&:/.>$&"G#"F*B?9D.($9(H=(G%0'";+!D*->/G=<F,F+=3=?<H6)G"?<@/6,80+2GE05/)28+22.G-0$&&8BE$E.8&15/"G#$91BDC&&28'
@r9767
ATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGANGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCNGGTGCAGTACAGCATGTGGGTGACGCNAAAAAATGCCTGGTACTTTGCCAACTATGACCCG
+
22G)7A0'&57<"G7@043/H&=C2A453*?7?&77/.6#('?>FB%$6"#E'A27##,%70C6'',8H&BF">H#9C:"1666/%E"ACH*,'<H#&G%*+-+;4950D(=!17%?D<2D*5,BD:F+&%'?@&+G<8.B;'.!33(.-0!)H151,D(?*5?")(43%2H<@9CC%4164#(%$G5?!@:5%A$1+=+6G!78('#@6.:
@r9768
TGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCNCCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGC
+
/>8E.#?$;<0>8+B<@"%C'$;*45G:+2*6$C$/..#$!#2!-+<@E0D?A-2G++B:=(?B9*)-A1<%06.G>$(9@G*A>F
@r9769
CTTGCCGTTTATGNCCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCA
+
@;7>3657E%%$+7@D"9?/F"AE$1C;$1#8H@6:(A732C'+H6>8H>7@=
@r9770
CGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCG
+
:$33BF9F+,1.'027,*''"'"DD0)2B%=@2A2)A)@'0*&+=G)%/*1>!$"C<2D)(FH.374A73H1-&3+8@C5)9H5:<5FGF48*E-;@BC<$C+
@r9771
AATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAG
+
5*6D#4D(F'H3'E#A"8(9B9H6B5%C;9,?#5-!C!&@411+H89715
@r9772
TCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTCGGACCAAA
+
/%25*H'''8'$3'%5#D"""%.)A02,%&!C"B7:4@8H$8!E;9B,2E!8;:>?9D,BB2B868:?$>?0C"'53@@82=70$4@GB)8-<'">',&B0'F%C<!:*;
@r9773
GTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATT
+
//8((C&0$-@5A@%C>)9";@F8"+<6*A'2?(3+@FD0-E(D-*EDCD@3AB/C(2#E*CA"!&
@r9774
TTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAA
+
7#<5609A)GC"25$)@D<(#%3.@3&-F:B@81!D&7!A,0(H&H'6:/$*275FF=B30FC&<?$98=!7.GA+0C<-,64$-79/8%/&%
@r9775
NGTCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCACCAGAACCGGCGCGTTTCTGGTGGCGATG
+
"!(++)***)#+&$**(*!%'*$"$$%!"*$""'*)$"*!(&)$$($%!+"("!%((%#"+("+)%$&*$'$$%!%%$#%+&#%'&#"()*!(#!!((!!)##(!(&$
@r9776
TCGTTCATCTATNGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCATGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGGTAATTCTTCT
+
91%7D3+:-(6$C)7"<6"A./5*D+*5%8#;<G5C.!#>+A(,6E&:0*$>D6H>04A%1<-+C,DED4AA?HG8>1$H$'B3=/02*>:=/-*91>!+@CB(
@r9777
GTCANGGCTGTCGAACAGGGGGANGGTGCGTGGCAGAAATTACGGCTC
+
'("'!%)(+%"(+'!%($''+%$"'((%%($&$!(&($#""((#*#'&
@r9778
CGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCGTTGTGACTGATGCAACTGACTCAGCACGCGCCG
+
FA-7+E$CAF53<"!/71>6+,?6EF6!)2--),;>CH@63%?4$'D8.3A+12DH.CB6#D.AD+@7/"/673F+"//91*64
@r9779
AAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAG
+
3139/$(12(1-2!:B)C006/36=3*+G0-&>C'H-&&(<8C$EG!><9
@r9780
NTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCC
+
#G#$<H)%/(6'+9+$G)#4%7??*<+650EF%'?5+1(%F*8@@A.5$#F04%)G/@&6<H6=B4:'0*,;?<!<#+?G0:'<!$0,%-*"G0&1370$@+G$$,;$<*!7=8A
@r9781
NAGGTCGCGCTAACAACCNCCTGCCGTTNTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATTGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATNACGTGTTGGCCGCCATTCTCGCGGCAAAGGAACAA
+
030&F?0?&ED?#A,D-5,"C,23@(9"52F(4'%G/G:&>5$-5-3/A=A@F1+#,4G:#.;#"#:E3>4C9&<(+.,>B)F&7$4.!DF07AD&(11B>G(HD/4?8#4@?;4#48D@D4F)+#%G&*A+6AH7@7"5-/3!G/3?27C=6>8'<6)05@FD!2@5$=!C.E9)6)4<'#<.<D#4"=4.@%G73=BH@$4"E+#
@r9782
NAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGC
+
4A+!G:A4:;.E9>-?4<H/..G=G!2'$3%',E"=">2-//
@r9783
AATCTGTTTGTGGTATTCAACCAGCACTGTAAGGTCTATCGGATTTANTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGG
+
,&>),2%=&7909(.D2=".1=-15$*0C)'#>/6A8:=54&*&!..0-=4/"9((HD/3%1%(3>+A+,)"D.18,=&@!+B:790>G/B9F#=6:
@r9784
CNGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTAGTTTTATCCGCAGACANCGCACGAAAGCTCTTGTCGGTTAC
+
)'++*(+"%")%%*&"&$&$)"!$##)#!#$##(*+($#!*#$)(%+*((*)*+$%))!()"*()))'+*#('%$$)*++*%!*"&
@r9785
NTCCNGGTGCTCTTTGCCATACCACGGGGCCAGCGCCAGCAGCCACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGAGTGCTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCAATTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTNGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAG
+
!&'&&)'%('$$)*+*(#!'"*(#**%'!($&#!*!#$!#%)"#$)'#'!(("+!!(!#"+"*$!)'$''(%%'"+())$**+#')$*'#*!!#+*!$+!'(#*$*)')*&"'*"#)'(*+((%+)##!''++%%)+!'!&+(')($!("(%+"$!)+()"$'+%")()&"!)+(*)%&(*&&'!!'*+()&+'$!$)$"%+**+%%%+"!'%"&!#!#&')'#*%&+'#)&(%)*%)!%(!"$#$"&+)%"+('&*"&*%$'&)&%
@r9786
TCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCAGAGGCCAATACCCGCGACATAATGTTT
+
?;,-.)!6'G.B=!?>=)F39#*"F4G9!@B/(/&4"&6,B0;"/!;1G1(%812(A="B+%"H;5*-&D-D3G+94"1?.?E<!,;@C(0<)H=35DA:@4!3&&$8@BBG
@r9787
NGGATCTAGAATATGATGAAAGATAGAAAATTGCGANGCTTATCGGAAGTGAACGA
+
'%(+)!(+!('%#*#%)'%"#%*'&'*'#+&(%($&%#"#"(!('%+$)%"'$(!!
@r9788
GCACTGGATTGCGAGGCTTTGTGCTTCTCTGGNGTGCNACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCNCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATG
+
-$'4+%A5-#352/160+9,:13%=:="D#-F20C43<*9+>3FD/*B5>D"0D(#&;,42!)?:HF21*5)%.<-A49<5;#H9='3#>$?<.:3&H7-6/@(;BE(*?"B>:0H+=.'%H>95329+%C!*A,:G8%3,@,!F=>C17
@r9789
NACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATC
+
%+G2G($D41=,;E=#&6;+;H.1A.E=2G'F2,$7><)4$<=;G<.E'"<H6F);512()==/"&B>)EC&$5&'5F);!+7")$1$@;!BGF%BA0)!#7<:/7)%'>$(*+H/54!&*E,><*BB#$&#&BF?>G'A*,-B3?E%#G57:$-9.D=?@/A:-
@r9790
CAGGTCATNGGCAACAGTGGCATGCACCGANGGACGNTTGTAATGTCCGCTCCGGCACATAGAAGTCCTAGGGA
+
'**(')%#&%"+*$($%$%"&"!+!&(('&"""+%#''%&(&**'''""&%(&'!)'%*(#%#*$'"&*%%&!'
@r9791
GTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTT
+
*/B&14&?.A".61EEEE76B4+D58E5%-(A3'FF,&4%D/A7'9"$87)'*A
@r9792
GGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATAATGACGGACCACGACAGGCCCGCAG
+
+$%*"(%$+*#"(#&#!'('+%"!'#&)*&$#(%(!!&'&$'")$&#**)"&%!$+*!))$%&"!*+%*)&&%)'*)(!""##%!&'"%)$!+
@r9793
AGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGA
+
7(2$,D*3H'-ED?:C&C<A661..E(<1CD<<'?4'H:&08'5+;BBE:?"A*$DC.@9+,:4
@r9794
TAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGNCAATGTAATACANGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTCACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATNAAAATTAG
+
%;3=1C&F)@+C0/560C.(-=H94?&18:A4-@-#@'-;1BH1*.F/C<6*A"08F-8,"E;@.',1#C;F:9<;(3#,&=(79/2)F5#37987:(5!FA@9C/6F!;3!3<)"6?9.1,A-*#C.C6E+'=+732131A$73#<.?F$5H!&9EGE>*4C5-+)'=<84*,3/H*$!2:..88A=!)<&<)
@r9795
CAAGCTTGCAGAAACGACTTTTTTAAAGGANNGTTATCACATTCAAACATTAATTTTTTATGATAAACAA
+
9284GC'<?&)&59GA3)D=G7D,C">$++:3B17#5)6#1>?-%-:G@*C13GA7GED;F*1"AE261&
@r9796
ACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACG
+
):B$'B9=-H9F;B7!C7C**#.44"B,.&)-@;?.(5FE!DEC76@1H
@r9797
CTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGNGTGCTGAGTCAGTTGCATCAGTCACAACGCCCGCGACCTGAG
+
)GF&81>*#9A6'*C)?-*;,<4#8/78"?H9+)2)96#0FGH-+!'(:'-<&G2?F7AC2@;5%"2-98':$4&B9E*12'(1A+>*;FGF",.(D36#H%996=#!,3',:,?7C9=.0.F;0(0C3?+<55?."E&0,5F?F;5D!B9H97C79A
@r9798
GGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGNTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCNGAAAATACGTTGAT
+
?,3'>@94C!F!>%A,D)@%686)32#@4((!C:/;=++)H8H-=-26*2$.;9;?!(22=@GD>"'-A9HD7"1=<,?/"4B(#(,"'36G-50*3D&H+:97'#/@2*4"%=*403/5
@r9799
CNGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGAGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGA
+
&!&+%)&$''&&#'+%+!&&'"$!!*'!!(*+'%'$$++#&)!&&%'+#(+$"($'#'*%("'!**$%&('(&+%+*+#%)"+(#"$+''&+&)#$+*+$('!'#)!&!)'"$!(%*+"+&&%#""+&'"'$+%!+*'+*!)('"+$'))"
@r9800
TGCTGGTTTCTTTCCCGNTCATCCAGCAGTTCCAGCACAATCGATGG
+
G.0<!=>A&C4C0+8%C!-H433!<')59,0H,+C?:1."C0,)GAB
@r9801
ATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATANTCATC
+
+E%)>,(B&93!>G'29-@BB1&A72>9>0G2"49.B+)'7;7
@r9802
TCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAA
+
6C<8#9/:*F)"=7D)E1:.AF+3-C(@EA@1%<"78-7H3(8=1.'5+**)(%%.083"
@r9803
TTNTTNTCAATNTCGGCTAANCGATTTGGCCATACTACTAAATCCTGAAT
+
!(&)(&&%'**"#$''%*'&!+$%+$)(+(!#&$'$))*$+'+)*"%)&#
@r9804
CACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTG
+
GEDC*>D"8(14@E>"&;982%#G('?@C@+(50(4659;<4
@r9805
GTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTT
+
6<E3$&C@EE4&2BHB(1;C&G#E%&+-;DH.;<(,;F0@0'%1<EF,1,+@:79,>&-;4&;.#>44%E73"1/:,&9B
@r9806
ACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGG
+
3.4!@D,*#2!>H4B!+D7F486#!E;9:-)52-)(0/@,/G@2:)H0?#,75*CH<>6./-+A=#0-9E2:.0>6#@@2E3-*$B>=)-G7=
@r9807
ACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGNAAATCAGCCAGCAGC
+
E;;G>*27EB9'(A0$A390-4><'A'",HB:#$G3+3+0$!213;+1$EE2H
@r9808
TTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGACAGAAGCTGGTAGCGTCCGGNGCNTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAA
+
G7"G$F4:&($9B3=,&,',1CF>-H"-G,92?353H1=;4H5D)9D+7;A#H1<6!A=BB+-G.!;;HG0A&+?)!C0)">?22CB/2<!EF4HE%F>)0:*57@<H/H=BA=!@7!EBD#:62,,
@r9809
GTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAANACTTTTCAAATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGNCGATGAAAAATTCA
+
F33"&=43*2$29A/$8A58"38,&@HDA910A-=:%>+H+0F%.GDH*)G!F%8(9F<)D9=C?9'1<6-(G-!7#!)*5;>48&<-90GE1+D2#1D2,A$8)-.;+!'G!F?.:%,+&F">BF"F.G600H$%9,0/565D+';6-/85?27/)
@r9810
TCNANTNNACTANGTACACNCNGAGACANNANNTNTTNNATANTNATNANGAGANCAGCANANGNGCTAGNNTANGCNNTNCNNTNANGANNNTAACNTGTACGANTNNTAANNATGAANGCGTNNTNCNNNNANNGNCNTTNNTNNANNNTGNNNCTCNANCCGCNTNCNNTNNNT
+
$#"$##!""$#"!##$$$!$#$""$"$#"!!$#"$$#!$"$#"#!!!"$!#"#$$!$""$!!!#"""#"$#!""#$!#"#!#"#$"#$$#"#"$!$####!$###!##!"$!$"$#$"$#"!"$#"#!#"!"$###"!!"#!!"$#!!"$#$$"#!$$#!!#$$$#"!$#"!##!""
@r9811
TCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGNCATCGGGATTTTCACCACGTCAATGGGGT
+
C#,.-++F18>&D)>/?$>;,!?3<E6C8%H(9;BEBH)@4%>64!:H5!='>'3#<$A$':1.)'-A.65A"0%%-%3!7#'0?'7-#:A='8B&=
@r9812
CTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCT
+
44*EH9(@:H17;>51:)+.81+5;23@;69!"?1"&3@93"BDH5$/66E?96D2C41&'@$&5-
@r9813
NNATNGGTTAAGGTTTCTTTGCTCGTCATAAACNTCCCTTACACTGGTGTTTTCAGCAAATCGTTAAC
+
!#("#&*&+'$!"+##%&$!%!')*&#"#+&#''*(&!"!(!("+*''%)'''*+&$$"#++"*)(!&
@r9814
TAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAA
+
)7'5G7$1?+#:.E0&?%H4#$.)83%;4D%-;1:2+HH)>((6.-EH$/A$1(*DD5/,C">60==AH-)#,+@>!D<B!:7:DB5H3@".G4$<
@r9815
AATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACT
+
;*#7#1$B11EG1>99'D%A/-"::9(!G;8=2$%F'=3$-(,95$:,4@3C"%6@,?&!F&GBG!(:
@r9816
AGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGANAGATCCAGTAATGACCTCAGAAC
+
E2%;-%=-(@986B:3@8A2>-&:$7G1>A#)&@6)F8E2+(#7GE<0;:;<8=*;GA=")4
@r9817
GGAACGGATACACGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAA
+
'#"#++"'%*$+#$%*(*'(')(!"##""+%")!)'!!$#*&+'(+%"+)")'!$*&"**#"(!#%'!#"("
@r9818
ATTTTAATAAAATTAAGGGTTACNATATGTTGGAGTTTAGTGTTATTGAA
+
<;H?D-<=2!.,!--=3%!'&!")F55EA81<*:5<'/+@#GB@@!(D3:
@r9819
AGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCATGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCAT
+
9%+./C>G&54;%GF&<5';(0+#9,E>%9'A+<+&B"7-)">@-?9EA=*2?-H(.$A>-($BAC'9%79H=F"2;68)20:,6*$"$.*%=759!:,!"<'E"--'">)0=$0&,64H"2&:!D16B'$,<-9H(@,AD48B=1:H=-F0,$2&#(%3D#$%9F*8.(#F?6"/>*!9/5H11(<?('98>0:F677+;HD>;<(
@r9820
TGANAATAAAATAATTCCTGAAGATATTAAAGNGCGTCTAAAACTGGTAGA
+
(''+(#)%$+'+"*$$&(%)'"#%&'"#%"!'*(!%!)&#*$)+#"""!$%
@r9821
NNCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCNGCAGCCTCTGTCGCCTTCGTG
+
"";B5A=8&>@8<BDHF(4036#*77!D"H4C8DDCH9(E.4=A4?)@9#3@96C<E*='+.!#AA3:=CE80F(<GG-C6*
@r9822
ACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACNGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAG
+
(,*A/E02!1*A$>D(%<%"<,+3)@7#D',#9871B@54&/'$&CH?F#&@ACBB5"<";301<C)%B)3)FBC<=5413;B>!2C;4
@r9823
GGAACAGGCANTCGCGTCTGAATATCCTTTGGTTCCCATACCGTANAACCATTTGGCTGNCCATGC
+
";!?7"5,*28+>#)G%G<,.;(H28(--6E,0C.;F330@!8"8/D:D)9:&E2:+6%&&///+#
@r9824
CAGATGGTTGGAATGACTATTCCTTTGTTACACTGTTTTATCTTACT
+
8&+:H;5"0*30!:/16>:?1<GB@*!'+)../-GE%%2$!-41=F(
@r9825
GGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGGCGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGCAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTC
+
*D3A>:%37%:!#!9&7.CCE,<1!-'%6!$%'32A3:DA9@'.H&@=0-10,<&8"'5!:(<%410==871G+G#$/@+@"0A7=AA1F8&BA<D'(#;$+(HF1#<F18)"<C#BEG(D.=/6+-
@r9826
GCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATT
+
3<@!1&!$8("(G!>?GA3,(57"5#5#)?/C*,2>7:D1
@r9827
TTCACGCTTACGTCCACACGGCANTCGGCAGATATTCCGCCGT
+
1;C90$+C:2>*DB--02(6E?,*;!4?"8:6;#)1'+*+8"9
@r9828
CAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGC
+
,F44&A#31:!8::F-D#=*$-D>&542(6D>69'106F7@8<#0H6A0<B&/<%4@HC2==1D6
@r9829
AAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCT
+
2B>2=+?+3#+8@"!6B>4<>G"BB(>#1,+@B;=7>C31%65D4("20121:1*.49'8*8?#:CD@614D@CE<&%H,4&/H7C(F3HG*99)%/5C>FG>&):&?H91.&:-H.G'E<G#4">(!G<7-E
@r9830
NGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGT
+
#3.H96A9E-397DE.C9D'H*'A<).2@H9(()?'.,:0*&52('/*,9.C<$/:6.5?;3A>467=37DC93!:+3!$@-(:-E*$DA;54B=27
@r9831
TTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAAC
+
7"A>2$?)%B4F))8,C!0/)*6>==8$*/5)C*185;#C:?9"%:--&<.A*:B&9115!-<F8H%%--&6-,,A"28G#DD=C6+$@>2<:.6G9=H6HA+<3D&!?8=&
@r9832
TGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGA
+
7:BD3?)-E#107>G-1"B302(B0?5D7>C$28;-1/)<@<)H+,H#1!2-AF7=).2,0%)2<6FB.B26&&'0
@r9833
ACCATNATCGAGATCTGCCACATTACGCNCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGANAGATCCAGTAATGACCTTAGAACTCCATCTGGATTTGTTCAGAACGCTCNGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGC
+
%;3/;)F&.8"'%)272B598B+D5,G3-$"CCCB"##D$0:1'F./3%+7F>936-4H@&1=+C"=D9A,-BA"%10GB'8@?5*C5$%A@$BB;8.(#>-;/4:>)C*6=/##!59+AE$(D5>A)#DD8A>H6+5G(&D':.2:?A-CCG)2+C3?;.;;6(4=AC$;.CG*8+243)51F<!@@A>--*:&?ACBGH:351.#(H<?+(DF7F%*E330E1:;>1/E%D8HH@+85&EC1G&5H1$F@</9&DD%=>?!9=;?!#5#),783'A);2="1,@FDD
@r9834
CAATTTTCNCCTCCCACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTT
+
?5;)HG*:5E6F2AE'208&H+D.16G-8<=1H55AF!7AH=86)??@C=<<1<
@r9835
GGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCA
+
E"-F-*74E91@.E?!+)1DE*?@3H4A%D6G"4E)$(:F,</H652*;=
@r9836
CACGCGTGGTTTCGCAGGAGATCAGCACGGCAGACNAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCT
+
AE'C<4#(H=+GEC%EGA!G"0A1+39#"F&!!*>'.&9<+8!@<;:',593=&&*2-4#3"69&";@4"3A.G($/=%(;/3!3.B@"EB3)C*GC3C(6
@r9837
TCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCNGAATTTGTCACTTCAAGTAAAAACACCTCNCGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACG
+
A#F,.?(%";8E(%,-D$!/C/+2/095&%&2-"8((:68EBH7'4F%/D0>"D171E=6A"7G1.#C?93-8742H:"C8,>F07="&$'35'D,G%'A;4GE-:B(7?.':A8H%$D.%FC5CG$,#!7&+B/1>)B5.F,+G$+@&*)/EE2)@2+=%:8;.BB*#1@D"4G-/2AB*CE;/&/'D%(9B3&G;B&",=)&?*
@r9838
CGGGCGATATTTTCACAGCTATNTCAGGAGTTCANCCATG
+
2('<GH1@.$D<,#:+9-*4.GA$AA59<$9<3/G,.=@!
@r9839
TTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAG
+
.#(A4@#85'=18BG7*/G4@%$!F'8D&H."12%;**#.A4G'>&10F+<3,?(;C87226.!@(G
@r9840
GGCTCCGGCGGTAAAGAATGATCCGGCAATGGCCGCAGCC
+
*H*CH80<&!4D./E"E')))G5500AA>8"'9:C2*(1B
@r9841
TAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTNATAGAGAGT
+
84*,&D%-3G4'&50H)0B.+5!%783B@;-/',?/0;)<FB;(>=$E@#?%2.H;F24HG&',<*#3!F:7#3AE<!''D!
@r9842
CCNNTTCCTGTNTNGNTAATCNNCCNCACANGGCNANAACNNTCTTCNNNNNNACNTTTNAANACNTCNNNGANGTACNNNNNNNANGNNNNNNNNNNANCNNNCGNNAN
+
$$#!$""$!#$!$!!$#$###!!$$!#"##"#$!$$!!!$!"#!#$$"#$$"!!!#!$$"$!###""##!$!!#$#"$!!"""""#"!##$#$!!#"#$"$!!$!$"!!"
@r9843
NCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCNGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCT
+
!B,C%B'?)>,G'G<81F:>C)//"(63*#B-B?E*&@(''CG(/"+?$(B+,,>#,E5C<(--D$3<E"""3?<F.))0B""4.
@r9844
TCGTCTACTGCTTCCTGCCCGATGCGNCTAATCAGTNCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTN
+
</(<>?7>-2=&)4<#6B)2B'>&()F@G=DF8&A0B!A22ACE#,BCF<"H3B-C=G!)<#3546@"$>((&1
@r9845
TTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGGGTTTGCCGGAACGGCAATCAGCATCGTTTA
+
//&-6$=+>:?-%E18)#2?B/,&'/6-">E:#B:>D3B:-@=9@0#3#.-4,8(%A&3@<9&60C,>*4-+"4.)A<&7G4;5-H*%:F>:
@r9846
CGCACTCGCGGGGATTTATTTTATCNGAACTCGCTACGGCGGGTTTTGTTTT
+
H=C<!7A;G3;:%>G+013,H+1"%H"C,?F#&3;EC8#=@/<,,<31="D-
@r9847
GCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATG
+
D(-AH@.*G+#4&6;!1F;'+6!5';/*;+#B)),F>181F9G.5=?8A1C1%BFD#68&>5H$1%4
@r9848
TGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCAT
+
-@8,>3/@5;!653?/#4/@B!2++H5)%"8:=C@)->B310:6=4+H0"62&/;*710,)E=9A>@
@r9849
TGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACC
+
)@*#;BG89;@;1#F*>07(+5"*G8.G(3!<33'/E/!3B*H%!G4%*)H+=G@=.'F4AE**%<<$:4!0)"&=)<E2#C%$
@r9850
ATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACNTTCATTTTTAACTGAATCATCTATTATTAAATCAGAAAGAC
+
,=4B$%*4?F:H/D?879F.&$%2)%GH45>*051E21.=)#85*G<)/53&$7=?E&+.?3-@/F;DH32%-HC>5#986-7(#
@r9851
ATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGANGTTATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAANTCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGTCGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACNGGCATTCGGTACAGAG
+
:H2HCD=G!1&6(+=<F;0D@5,2%$-0/(E80&6+"*4!C"&.#/3$9>0:?FH%'D+,:?>689-79DC76=$2!ED(%H=/D+"9?D);$C"E%/610*11?3&5+2"*)55($9""%&*7A>D<@=-!94+D&GB@FD.0D(FG0?7>$46*12,3;>.C.2#B$F!F'@!E!/GEH@7&$8"&-D.2:D!3(C0G95>D5B+B@%&!>-D*+(EH3H7D2+(5="&E%D!8'#7>8)*:/+D"=?/!$$((?)>&>25D%C370.67/D!G,)A@#85.E0EHG>>94(&D@;859)&HC3A="&7E%$&31?4+@F3$B*4/?B,8G0.8H0-3/H+!<7CF83=2</"FH)7>4)<B10':'2E9H5E9?2*(;17-*9E#:4H)@#2)*C&>D)88@B%5>5B32+*##1C708$1,,*D*$'E)?(CH7B0@%>
@r9852
GTCNNCNCCGAAAACCCCCCGCGATTGGCACACTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATC
+
&()$"''&++'($$)(#+%"*'#'#"&#*'#&&"#'($+*$%&+#$"(%#&!+!(!(%'&$)(#!!(+""%'#%**&$#"%&
@r9853
CTTTCCTCACCCGGCCCCCATCCNCATACGCGCATTTCGTAGCGGTCCAGCTGNGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGA
+
((64@#0@?5-@#(3(*1"!C8150=<D;A>=991@A3($&+%8@2-*F&9;:D&0HE+,!)G"'4'1B,7=D;9:"A'B40>@H%-@9##<>:-,9):1D(@H25'';D8??$$>AE0GD6F857#D+.9%CBF9<=,G5?.;
@r9854
TTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATC
+
#9@94&#4+%(#G=0#6H)+'=,1#.>#"3&#BDH?5-E:,"77"A0?-C'H8=7<FA').?5((,H)??>'FE+?>@,(!-@8.4DD5H1(<HC3*?:AH#+*542,3#4H*;$E&&/==>+>
@r9855
AAACGTGATCCTGACGNTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCG
+
/H(1;:C)9)09>B.49,$;)@=037'=/-F2@:?#)?0D=>*!#<9/D%>2/*4$G4*0?F6=:-60=)671AB=/.&C(70/6/B?$7956B<H"EA!BDH?1)8C8*"(C2',B(><&%<2*E6>%)+,":'3?C=C5G18A:*32
@r9856
TATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCACAGCGCATCGCCGA
+
CG7(=>36F'/F7@@$H(E&<B?2455'+8"E#.#;&D)#-B9E;>*=BH=BG@>-)G#"5?")71+18+3*2)>=9+E8!%:
@r9857
TGATTTCGGTTTGCGATTCAGCAAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTCTCTCTGCGCGACGTTCGC
+
-*A.;1<EF*79/A"'GF=>%%<C@7!E533504:.>0>7#:*C3.#G*%$14;5B+'==A.E<@4/'"6997="+2'>1,D*7046F5-.##:0H:+930C64"7-%&!<"9<E6
@r9858
ATNTGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGNCCGTGTATTCAGCGCCG
+
2@?&:%D!/4,!2HE<)3A59F;+$.*+!36D,6;4#464F/DD<)50+;,+';*C77'@
@r9859
TNTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTG
+
&&%G<6%C1:*96<7D81,A-)>,:B1D6=<!F4B/1#1)2:-(H31.,(!*BD
@r9860
GAAGGCGGAGAGTCAGTTCGTGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGNGAAATCCCTGCT
+
%$<4-#==5(""9#"6.(.$3#86;#33'&E"2@:3/HC""?!6!4&%F#?2"-A%"?*?C2+H;E.@"D;11*;3CG
@r9861
GAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGACGGCGGGGAGTGCGTCAACGGCATCCACGANGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCACGTCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAG
+
;D>1:A,:+2C7527<;-@/2:=?'>$G,)2##$H4=G3)HDDBD)D4:0,*$@"E4=E;E=;@2,C,77?>.=*17.=(4%"8!;>)5?!.68)='3@36%=(*G.>G%B98$%#E/*,5''8(&@9F:5%(*0#@B+)60&@24=(-A)?4&8.$;,EA+C0;B,9A76AD9F""H+$$14BD2#*910!&D*E7924:(7/,1>'@'303/43B)G-8H8E4--<3B*CD/4>%0
@r9862
CGCAAAAACAGCGGCGGCGGGGANTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCNGAAGATATAGCTTCACGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACANAAAAGCCCACTGGACAGNCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACT
+
700A;$H(B'*02D89CF9'6+0@&E"C%&;(G/7E;A%!D:#3.(.0H+#)?)F=4(<;+%%<3!5'1:7>7;19!(./*9EC46)F&'.@:.1GHB>7FD)G%+"5@>H/$817E2A%&E..5G0B6-:$()!=?.?+)'/69<7$"0,""22-"5@:"/DGH)*4-=A'H8A*<9FC048?"'3$44D&C/=40$+)%4E;*$8<@4.C&$&(H,%4$7>'+F,HFD#?H6",'EB,E>,'@*GB8*8C,59;CD"/8D''CFC+H8C?)B%%%93++E(1?&0.2%'7'7,+'H?2)&1*<H!D;*)=-B<<@4C:>=FD=<4.A%:B+*0:7-GF?75&"/?40+!:1H1&3&'$.G&2'+;49$H<>5AA?<*9A9.E(8<6/9'
@r9863
GNAACCANNAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTA
+
#")**&""#'#+"&''!$('!!+!))#)!('+($#&*+)$)$#&)#+)""!&)&''&
@r9864
GGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGNCAATTCAAGCGATGTAATGGATGCAAGCTGCAATCG
+
.H0ED(303HBFC#6;9/!15+,9B<%>64B(B0'A6-*H$'D:-.$&%77FC0F12)%6)$F@>E-E-E;6@,8@-&>DDG0
@r9865
TGGCCCTTCTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACNGGCAACCTGTGACGCCGACTGCGATNTCGCGGATGAAGCAACGCGGTTAATGGCCATTACGGCGGCACCAGG
+
2$;27A5B7-=G!AHE!15!;88&;A+*E%%H,*5-2:H<40!.F(F(1"GB3!9)8178GHD"76"/+:65)!AB:E&+H%:=4E"4$#(;$)7$3(4112102)62"5%C(H!;3A$3D=$601G%EH
@r9866
TCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATAT
+
3!D#%48-"$(8/!?<7.,F(*?8!2%D<:'8#GE"$B)E0EA3-.048&B7,@#B3)#(9D:%99@"/9*3F1*6'><H971#D8'%'>)!CA
@r9867
GTAATATCCATTGTTTCTTATATAAAGATTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTNGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCNATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAANGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATC
+
48F@(1.<E2:(1,7<8/1/$A'2GC+28<%(D7@3=6%+;(H&5-=45$09=%DA5?/&*1BGB7*'+!=4D.;))&17;+$HD+E((8+BD.@#@#5G/#DH7AE/E!ABA!9'=C6<+/FH@98)/,!8B5:,*494!6-G)-EH-EE$>"@6*7,.:;8@7'C$9H=!8,B21!6/0!808HBC:0-2%@*/3+B.,"1',;2.)A#,2'4.F/D7B$57"&F":3G14D22D(H9?(A'4#'/E@HC75%0.9D,'@.D)0FHG
@r9868
ATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGNCAGAGCAGGCAATGCATGACGACTGGGGATNTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAA
+
:6(.2'8&?,@@+/0<2<69%F973GHF+;0>F)*(:.E0';+(A?<0E>(,"3-D-%B#;3H6*=-+4?;#=7)C&201';E%"B5&"9"C-<)/?&84>G#7A.B--7)H(1,.1D">?H:6B58;7!&"A="''4A(H00?(:A/+<0';0,)*1?A"DD!0/5F"C;!DE"&8+92#96?.'E(6"*D)H3"2G4A>49>+9%EC>D,<A(+A$&08"&'8*,(F#H5//$69B9>56(B0.>"FF=#4
@r9869
CCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAACCGTCTCTCAGGAGGGCGAANGACNAAAGAGAC
+
'?60BA5=!,!"1+A7G)'5>%E<E#H+2/5:.-*;B#,''1@G=/;'(-B5<@/0;"7F",1<3'ED#?%;>49)!
@r9870
CTGAAAATAATGGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTANA
+
*>3.%*G,1#E>/15.4;$,F?.+D$:B-@7!:5/9FGHA%$3HF.-G"=GCE?;%6=G%"?&C$'A@G;0E@85:D2@GB:A6#A+H-6,$DB3!89&."%2/GC'(**"#6>/!D7C(A78)F9EA5*',E.&(G&#/1
@r9871
CTNNATCAACTTCNTCAACAGNCANCTTCAGACANTACAAATCAGCGACACTGAATACTGGGCAACCTCATGTCNACGAAGAACAGAACCCGCAGAA
+
#&!!*'##$&%(!"!!%'#"!"&$$%&&&+$$"))('(&!++&"($%&*")"+)%&$"+"#!"+!+"(++#(!****!%$$'*"+#*(#&%)'"+&+
@r9872
CAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACNTNAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGG
+
8>)%=)#"FD3#=)1B1!H1C*2D8'3160=>7@6"95=253BG,CCB$*DBG8"62/D#&(>/:9'"2E(C?<*B1&E:=?@H@;)'A?2+#6-3$*F)&G@;F9(-"75(6A"0AH1#9&911)9&-9>@"9<5;,:&@E)23;E')19='9>##:A"CH5.BF(F.(2/G.:7&65<<&:5A*&/(D-:31H
@r9873
CTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCANCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATNGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTNATAATCATGGCCCGGTTTGATATGC
+
E##<;,C<-!#'A#<,(4@!'6()+A.)44?9&+'/=9E0>(7).+02DCC3D*"C/>4;?=C#$'H,'?4A-:1#"E30=/<D2F<A'<.F9??EH".C1"'=#4D#56)9D-C:4'='2A>?23*(=/.H"$=+%/>/;"4/52#<H9HH62/$B-2C2+D//A6G8/C2&.&"#3/9F0:0;1/972:<70F+(F*%:>>(,!!?
@r9874
NACGTTNGCGCCGAGTAGATGNAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTT
+
'!%)"$"*$&#+&+%$&##)(*+'#("!!%$$%*+&%#$((&%%+&+('""("+*")(
@r9875
ANANCNAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGGGACGTTTGTAATGTCCGCTCCGGCACATAG
+
#!#%"&+%)'+")(#!)$$)''+%'+(#)*"$%$$*"$$+!'!!%*'(####"&+**))()#!$*!!!+*%
@r9876
TGNCCGTAAGACGGCAATCACTCCCGGGTATANGAAAGAGNCGACCACTGCCAGGGACGAAAGTGCAATGCGGAATACCTCAGTGGCGTGGAGTGCAGGGATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATCGCTTATGAAGGCTCCGGCAGCACTCTGGTNGCG
+
&!'+)&$$##"''#+#$'%)#&(+&!)()+$#))"$&%'++%(##!!''+%'#$%$%$(+#"!$%$(*!*&!"+$%&++$$+*&#&'(")#)!%!+*(+"('%)#"!"+"*')(+*)"!&'*(&(*%+%"+!'+&"+$$++$)*$$&'#$*&*'$)*+$&$)&+($('&%'#
@r9877
GGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATGCG
+
=$2=574(G9.G8FF$E++*(#6$;/=+)BB%94'ED*&;42:A#8??%H3=21H0"F%/=$009@H0&6511;:&)DH4;F*:@)<;C0(DF;C05!B9-A57/6<?,"/?;:)+
@r9878
TTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGC
+
F0?->$49&"*23((3+#BHB:8DE(/E!?;E'/H%C&%/0#(/B9$%#@1=$E2:14/B"02>1<0
@r9879
CTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTG
+
<E53.197G.%!A)F$6;"G@,?=@F,>-A)0E1:0C(E!35
@r9880
ACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTT
+
0@>':F(=E789(=2@A()+%??C.#&.&%$H#(7@0@.D*(38B?$B'94<,/#)
@r9881
CAGTCCGAACTTAGCGTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCA
+
C74CG0&/&A0-5/E>32=;C$+<7CF)::G8DD6;GC,G9-;@)0=*8+*:&(9:E/EH1.D8EE&%?H2
@r9882
GNGGGAGAGTAGTCGAGAAAGAGTNCGGAAGATGCAAAGGCG
+
(!198@E66&71.CC-F%AHF.@1:(*A055@#"?.F(-:(&
@r9883
TAAGNCCGGNANGAANANNATTNATTGTCCTNNNCCNCGTC
+
%&%#'%(!***!&!$!'"""')"*%&%($)$"'")#)!+'!
@r9884
GACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTGCCGGTANGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCAGATAAGACGTGGACCTATAACCG
+
;H@F0-3-6A2*@)D@/@E:>GBG(+G25#",@*E%(?7%"0?)98%A+?)=F<GAHB96!;#)(3)F7A<H<'7C5EA&66G=G?#F4);)&(9<),"@G*#%(G1=BBAB/<%A:&+4+@C."#1@(%+=B2'%H5H67/.;%*F*/'0#=#"##8)G0BFH>)H#"&B":/+"+""*A3.C@.+#?!1,
@r9885
GCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCACCGTCGCCGCAGTAAATTGCGGCGTGATTCGCCACTGATGAACCAAAACAGCACAAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGAT
+
'6D=.*78("D&3)?;>#/%0@$@<?6.:E5;"/$ADAE!93)D:$'A0#&3!#2='3F+>)2*7H%;!(-"AA<0-!%D;B&'49E)@>31;%<2+.C8&/3?0*B--+G42G'028A'FH@'CB*(5?=F%CB)'48'E.6&&6+#(?<%EGD?-F@0(BE49+9)@C067(0?D3??;C$7(;=7F90;@HHC85"*5/+2G:C39!
@r9886
CGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGCGGTGGTTTNCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTAC
+
.EC1,%DG'C&+,:=C+/?6*('#;?;A?-2B.;13;A,6#;9<'/>>F@,<&!)9EGD8F0-<("<A'?>%;D%9""0,/=+7A*=D<!C#-2?!<)CC(9>*.%!GE0C783+*:6A7416%>/*5+377,HC$HEH0:)&8B:+2*&5B.D;8;@2$?$:+6A>"26%4C,B1+C5:?)7*#+.E6H/HA!A0G*2+6,-H6++8D&68
@r9887
AACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCANGTGAAAAATGTCCATTTTGTGNTGATATAGGACAGACAAAAAAGATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGGAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCA
+
6,33@./-%=*9(G/94:0/7)9,+>"4D'5A12"?/''*3'-CAE0!2*9#E90E':9.'5210.E<'",;%!1;,D*$/5&.,962D/:;?/564=:;-,G.CFH99:"=-7/=A$)/1E-6;06./02?1$1/'%/C9:F+#2@<+(=B"G>0"E()E$DB3'7-@!<9:<D+*132G&"4%3/D-/GD@:E-B:#,3%=FH9DH$D/3:D?85485(@"FC5G3-G3G3828?47%AE=$BD=)?"-(.,74/;:3?"(-(EC/0A5.9*<=#)!;"-"@!6('&8/=$+,3G1.(9#A)2?>@7'#G@C>@0+=18A:#AH!/08%C'3(8#E,!E'94+'(7B:GE;6.3F=3)/9<@AH78)H(E&E$@;()!C=F66<,',B<"-8GG-9*(E>24<+C7&.,@HG+)2*390H&F)<5#5B'"?C@<HG8?
@r9888
ACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGTTTACGTGCATCCAGTGCATCACGCATNACGGT
+
)D?G7+"!G3"3;>?E!#D!08",1,G<@&0;94D/5!EA8G>?',9:<:4+@+5+:8/0)#*F3-BG'75'"9=<CF6)&
@r9889
GCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCT
+
!,&4H@G2.*6%06,68B4<@)?-D/221@/.;!-?C3"<78'9$!9"899/A/DG6)'=/CA5#--F
@r9890
GTGGCAATCCNGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACNGCGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGC
+
FG?'+=AH1#,*GC!9&!EAF9?5&H68&6C*9=,,08@FDE1B6+:+2?)B?F%#G>!!8.G@7.)62<A-D=$0A-)@@>),G-6.$'=2-0>3E'#G06B.(68$C5A%-&4:9
@r9891
ATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGCTCAATNAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGA
+
74"7"@"4#)77B<:>'HA*82'(*G*2.0?5@(>?2;0!=%266D?,'47*(/'92&3G8&3F@.H68AHB7H7/=#78"HGH&!2H>!GB0H66771C23?
@r9892
TTTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGGGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGNATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAGATATGGAACTCATCAGCCCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTNTTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGAT
+
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
@r9893
CTCACGCAGCGGAACAGTCGCNGGCGCAGCGTCGGCAGCTTCA
+
@@H=$@5!--1D4B<(F>,:945*9-02,8@:/&H7/?<"'?5
@r9894
ACCCCGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCNATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGNCTCT
+
2*(>0?57E*CG=,#<3:/C3+!6,F'G+&.@)3C4:$,/0($3+)53E2"2%AH9F."A4!0GF!2"?#2G!GG>C/6:!@6""#(1<>C?F,F25)F8%-EEF+FA*G:G.%-+)'CB!%#=>6)7&AD1.)'7/4=?92*GHGF;43=8#"3BB!4=A,<>+71":#>D.'%C*>B.3")&2B;D6
@r9895
ATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCNGGGTCAA
+
EH*F2>9B@>FE1:+9)#$8,A#2:%/#&D76/<0E'F;#:B#9EF:C?"H-)E<C.2(/(1/;$;)72$760%$E=14(A)$=
@r9896
NNGCNATNATTNAANNGTCNNNNNGTANNTNNNGCNTNCTCGNNTCCNNANTACNNTAANNTNGNNANTNATTCNGNCGGNNANNNGTGGTTATNNAATCCANNNANGGNNGNCNNNNCNNNCNANNCCNANNGNNANNANTNNCTNNANNANCGTGNCNNNTNATNTCATATNNGGNTNAANNNNNNTNATTNTNCNNANTTNNNGCNCAATNNNNG
+
"##$#"#"$$"#"$$##$"!!"!!$!#!#$$$$$$#"!!!""$""#"""#$!"$!!#$$"!#"$!"!!!!"$$$"$"#"!##"#"!$"$#$#"""###$#"$!!#$#!##"!$#!$!!!"#$$$$#"""#!""$""$!!#!#!#!"!"#"#!#"#!$!"###!!$$$##$#$##!#$!#"##""!!#!!""$!$##""###""!"!##!$$#!!$"!#
@r9897
GGGATNTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACG
+
7H0./2F3A*#+B=<!<!#''-"C"!<+9;</A+E4-#FGE136G;0&?G2$CC9A7'D0E$:,5-G9+B5?,(#2CE4
@r9898
NCATTNTNANATNANANAGAGGATGGGTCGCTANTACNCCNAANGNTTNCGACNGATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTNTTGGCAACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGTGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATA
+
&#**)%&("!('#)$$%&&)")'#%(%))#$)(#&)&#$"()$(&#")!()$!!"+$(!+&&&(!*"%'*'%&$#!)*%!("#)!#"&+"+%)$#&+")*(")(()!!$$()$'(*"''+*"()($))$"*))$##*$*)&%%#+'++!*)%*+&+$+#")#%%)#%&(&($$!)*%&+!))+"('+!*+&$#+#!%#!*%*)%!+"*#*$*(*($)&*!*(&#&"#)*"'%#(!+'($$&**!++$*%($#+&&)"**#$%$%)+%(+)
@r9899
GGCGCACCTTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACC
+
+*,H5-(=G&+)!$,6@.,@CC>-F1:(@,%?%E%&1C>9*,6>,1+23A(4?%A4%-G*G).$*0.26FC!=B:)>;%G!!+;B-:6A-(E%!(1@>E25/'6>6"<(-?+,,7"
@r9900
CGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCNTCCGGGAACGGGCGTTTTATTATAAAACAGTCAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTTCTGTCTTTGCCGCACTTG
+
%=H>",7(BC,4200/+3!7F#2/A-?7("%;83G!-A&26*BD$5BGC8,FB)4)7&%!7.>+G.%H04+8,));%'6:H!9!"1E#1$C"<;%<A6@",.'A'(7$!'9/F%44AGDH)&96B)0B&C%#%+?>A$$-"@
@r9901
GCCGGTGGTCACNCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGGGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTNTCTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGNTTTTTGGCCTCTGTCGTTTCCTTTCTCTCT
+
+')(+#!+$((+$$!"$'#(!+'*#)$$$)+*$$$%!)!)&('')++&!!&"!"")")##!(!))"!($'+$)(#((%*%#)%('+*"""#"!*#*"(!)#(+%$+($&'*#%##+(&)*$##))%''$"$')*%)&("+**%'+$&"+&'++*%!#%'+(+"(+#"+#'%!!#!*#%#(&++#!"%#'"#(')$"(+'%"%#!*
@r9902
GGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCC
+
B>-?'78AA:5,9"4(&EG#12H.(3C<7<4/>,39;4+H99AAH?$"1
@r9903
NNNGATGTTTGCGCAGAAGGNGTCGGCNTATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCNAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTG
+
*(!)%$**+%!'((!*(()!&"!&%$)%"+%#!##"'++)()+$''**#&##%")"))(#+#&*"#+""&%&+'#")(&'!#%"&'"*($%!!)#")()#*+""!'")'+&"#
@r9904
NCAAATCACTCTGCACCTGCAGCCGCCGNTCGGCCTNATTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGNGCCACAATCTCNCCCTGCATTTCTGCCTGCAGCCA
+
"+')+$##$$*$!')%+")&#'*$$'"%%*#$*$#*(&!*((*%!+#%'(+)#")"()#++"$%((#%()*#"")&%(#!#')$)(%(&'!(&$(*)'"%$&('(#'!(#$$
@r9905
CTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAA
+
7?&6?8;&2@/#F3;E2,?<=4F!2252%:><D864#D,C'(H/A>!+#5!7B:5&.?"F8#?60?&?=H1&3
@r9906
GAGGGAAATACNACCNACAGATGTANGTAAGGCCAACGTGCTCNAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAA
+
+"#%&&")&!&%++)&*&&%*#%###&*("(+!'&+!(&)+"#'"#$('%"&))'*+""%*&!!!#+(&+%$'"$%"'*''$)*&'*!+%!'"%&$"*"))+("%+)'%#+"$+&""+##&!!+''%
@r9907
TCAGCTCTGATGCCAATCCACGNGGTGTAATTCCCTCGCCCGAAATGGTCATCACA
+
0@7C/E"&"/>=.C8*B(&C1?1E140$5-?42:04!/=2F&"5-0D<$17EC)H*
@r9908
GCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCNTACCCCAACCAACAGGGGATTTGCTGCT
+
)1!>&@7+1'=0A2D&?/?H%,$'->51BD>HA)66F7@(<!E'H-8+C&!464/G+&C78?'#";*"%AFB%2>"79#!&.)#,563:91+E8E<+2:G<%0?=@>:=F$@*1H/=2F<;+!',,&A?!8;#B(CC9:);7@-(6*'0##.%!26.ADD8H$#+HA@/G
@r9909
CTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGC
+
H-?-9>):B+1'4"!!=5$)"&(>5/6-6D(1$,/8=G&?;;(*0$(=)
@r9910
CATAACACTGTGTTACCTGGCTAATCTGAATTTATAACCGACCCCAACGATGAATCCGTCAGTANGCCAGTCGCCACCAGAGTGCTGCCGGAGCCTTCATAAGCAATATNAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATTCCGCATTGCACTTTCGTN
+
!@0);+@7:1*>%&3=H59>&H(,9>D&&CD1&A5F)0$@,-2;/8;"2*,355!D4+'*(>#E<&<5.9ED26G?#&%+G;A<8(1$$G<DG:0!EG:%#G3-E7/'F$(36).CF3F@2DDBB@8*BA(:>20<(""F?:B/0H7;7-.:E737G>=H)2'E,&1F,(H7"!AE$"!E;A#B3$5#
@r9911
ATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAA
+
=#-H#==;70'85D;<F$HHGH).B>&AE3=-.%1%C(="D43C')9&1A(B/55H14;C?.98/G'7=8B&)(C/3&3;
@r9912
ATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTNATTGT
+
H%?=H!927?$$E4=AA.5C8!56%9:G/##2$%<8;E-<,/(;E!'-+>)!;!FG$'@-,H
@r9913
GGGGNGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAAAAGAAATATNCCGCCCGTCAGGAAGAACTGAACAAGGCACTG
+
'$"*#&)+$%"!+#"$%"+%'$)(!*$#%%'&$'#'!*+$((#'+$*$%!+#%+&$&+(!#*$%'+!*%(%+!&#&(##**$'+
@r9914
TTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATNCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGAT
+
@>6(2-F)3$D%'F7703(1%"G866:4&,%CD)=7C"&6(+AF$3=A.@@)'<(7(8422&)3D>#=#HG-0.!G-ECGH19+(%E(
@r9915
ATNGCGGAGACTTTGCGATGTACTTNACACTTCAGGAGTGGAA
+
*?0-!)0.G>>4F2A!!0BE#("2-B"#,81"><<='1A8>&C
@r9916
GTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAANCCGTTACCCCATTGNCGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACNGCGNTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCNAAAGAGCTGGG
+
+5)!%"@?$FDHG>BFF8.-;!8889+*3H.(%!%"*'1F+.3A%?3G)?)(>-1?DB;0)0<3?4=(<&7,#9>30-'8)2=E&BB$9*$0?4'G,'48>A'$FG9<2G.7F('2/;/<'*0$EB$2.?))7%)4)H==!:77>8+"4C@$HE"EB9D*9='B.)+E
@r9917
TATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGANAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAG
+
3D/*C8++8:*E9B-:)37"6&F#3*"*0GEDF;D9B,E;C5(7C?-<$H>H,/DDG5/*'D%H-G#2*'5;138<4+6.%$<?8?;3A,83H;@AG%-!B>D:-&%':+%C-0@!"8F#/$CH.H4B<&0/B5H)$D"3@&B'<7
@r9918
NGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATC
+
%G3-*!6)5FC.1?://?96A!6&G08/%"&@#C6G)''"
@r9919
CTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTG
+
30%($8,-:9?E?!793D?0A:1<'5"%@%985*$=F=8BD6755AE7E30(/')E)4%,2@42DH$H'!D:-?;;;3!,$!C,@HC0+B-E(';:&8)7:&&!!*!?6"7%'?8-?&E$
@r9920
NTGATGTTCTCCGCTTCGNTAACTCTGTTGAATGGCTCTCCATTCTGACTCGGAAGTGCATTTATCATCTCNATANAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATACCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGTTAAAAATTTTCCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATANACCTTCATGGAATATTCGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGNCTGCATNGANACAAGACACCGGATCTGCACAACATTGNTAAAGCCCAATCTTTTTGCTC
+
"&+!%(#%#+"(**"*%$"&))(#*+("+!#%%%$$)!"**'(%("(%%$"$#"+($*!#'%#$)'(&*#(%)$*&&($#%+*##*'*"$)*&)*&&%+&)*"&"""""!)#"%*()++$$&&*#&$%'#*&$#*&'$+&#"'*'*$&#*++"#!)&#!###(+%*%+%"'&')#&#%*$#!!*"#("%$*)*#'+)(&%&!&%++'+*+#%!&('((*%'%*&*!+*$!%*&""$&$+*$!"+!+(+)+*#++!#$#+'*''"+"#!"'$%#(%&'!(+"##*+("&''%*(%$'"$("$''+'+&'&&*%!$$*$"%$*+%&'!+%)*!)(&'#&)#%)&#$$*!"(*!%"(*%*!"!%)*&*#!&)#%'+&%&$&($#'++!$"+**$&())*+*"'#+(""%'
@r9921
ATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACT
+
A%0"A)6$!76>-2/7?B"&/,=#@.E?48,,:A:?%G"/+,2/),=1-FE4F3%343,1EH
@r9922
TTTTGAACCCGTGGAGGACGGGCAGNCTCGCGGTGCAAATGTGT
+
D(-F:37-0+$6=03G7H/2(??2#6,5ED2)29/%%0(05)>.
@r9923
CANTGANTNNANCGNGCAGGTTNTGNACTGANGGAGGNGANAGNNCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCG
+
)(%%'&)*""$!((!")(*($#*%'"#$##%#)%"**!)*&%#($()#+"#"%$#%++*+!*"+"&*%*"%%%($%*+%$%*&+(*$*&*+)$#+"&$(&("%'&&%!%&$)(#"'""!(*!&"'"(!""%!)(+*!+&+))(!%%##*
@r9924
NACACCNCATANTNNNGAGATGNNNCNAANNNANNTGGNNTNNNGTNNNGCCN
+
!$!"$"$#!"#$"!$"!#!$!#!!!"!$"##!$"#$!"!$$#!!"$#"$!""$
@r9925
GGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTGCGGCTTCTATCAGCAT
+
@>G:)<"1/8.+07?/28C27D)E<>58#+H*B!3<$CB*@"',D8>;?CE"/F85&;A$B58A$%B%+"0$1AG7?2
@r9926
AGATATCTTNCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGC
+
98:1217B1BH0,:'%?!::7E>-!#?)!62)$$A<'9=0;B//777
@r9927
NNTAGNANAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTAAAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTNATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGC
+
("%(%""!((&++((+"((%+(*+%!)!)$!+++$!%"+%*)&)&!"*&""#%+'"(%$%"*'!+&!%""$'#(+#'$'!#!&!)+#&'*$)')%%%#''%'*#'*&!"&$!%&&"''+$!#($)#%*$'%&'')*(!()+!%#%+%%%))$(##'(&#))'+#!((((*#'###'""*#!%*%**+&(!$!'&#%")++!$"#'*))$+*(#%+'!$#'#%$'"))!!#
@r9928
TGCCTGGTGTTTACGTAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTGCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGGCTTCACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATAC
+
>->1@)A?5:)$%:G?60G(!);8D>8>H=/D)=(:9,,5FCC-1+DDD4%12;9F9?+B!0!@B::?>"/60-+H<F8184.F+B--$!'$%F.HF+.?H+81BA@07&?/5731,!;HG$C):=7E7=C,2H!C<C#>@F&8BC;793CH9!628(0)4-HFC?/AE'159.3=B.@BE1B/2:<D*7$2#-&=2@1(<<310:">//=*36A<19//+.A@$0#G=91A=C6=HD!GB3:,5#46"C#/B%:1:A<A$D6#,0F.'G*=3E3G5-(/:@.%(>H<"4/;'=6>=%&!><#680'"4A<4"##0F)+,85)/"D+
@r9929
TTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCNAGAGATGACAANTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCACCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCG
+
*8%D:EB&)>1<#@<03?/3D!:6E2')"/##;=-F$80=HG7"?F#>-*7<0*@><-91)6&G+$D<?4D,$=917E(.%D)/506"#)<58.E=<'B!)?C7$E)6>G@-2'-9>,(1!B%=<#H+%?8:%0/#E;5%-0)EE7=(H@9-'$$D31<8'22/7"8E3-7B2H8)
@r9930
NTATTTATCNAAAACGGACAGTCAGGGCAGCCACAGTCACTAATTGTCCGGTACAGCCGTGANTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCAT
+
")5%E=:F;/*2@D6&C$3"!277&;!)4F>2%=6G2*-2&7;;H+5$6<9#H6/.A!@<G.G@/3"4/,'C?6&/H/37D=38@80-3)%H93)@17%8)-1G(81-A
@r9931
AATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGNGGCAGATCTCGATGGTGGTTACGC
+
2=4:GDE>AE@E%DD!4-+3514#!',#BB*,2>G.2+$2:GA:EH(%@$A5+G/-E34"/H.*:%,'2)(3
@r9932
NTCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCACGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCCGCAGTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAG
+
"&+&$(!"*"+#&(#')#*&)*&+)!$*$(&"*$&'%(&*'(#&"*"%%))&#''*($%%)&&+#"**!"+#'+(!'%'&++$+($#%%%'(!%(#+(&+)'($$%+"&)*('$#"&)"($$"#$''!*'+*(*'#)$&%%*&!#)"#)%%'"!"&*##'#$*#!%#'"+$)"+#)#%*"%
@r9933
GTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCC
+
B6%%3#216C8E=#<537C/+?'.!<H.;(;9)>EA4>C7)H&C3B4(=B9G8)DF$
@r9934
GGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGNTTTGCGACCNGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTT
+
5@!=-$!9B<)..:->@.08)-)F%F,#14F&=.+51*"<5"6@$1;@CF("==.?0357AE(<5($9A<+3'BA&&$*&>+969+C<%!9B.#*H2(6=G$21+=+;:);%?&0H629"C54%'!%E<7'FD%2:64AC"A77;
@r9935
NGTGGCGCTCTCTTCCNACTCACTCCAGCCGGACTTCAGGCCTGCCATCC
+
&?0E./5F0'<'829/<@CE1("D:>;-=,11B?*8,!.1E$3E1(56@@
@r9936
TATCGTTTGGAAGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGA
+
9>?,@,7>31H0.H.&F=-9/2?<*$-#HG8D-E)/?8"*9C<"1'A)E#C9)F6":HD*49=)=1D?1/=CD8DB,2A!(37)<+++H#B7;C8#%"0?'A3;=:>9";B'ED"&6B=2>;@A;,B3.C8%%
@r9937
GCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCG
+
54BD;GBAAB:>,&7&E,6A"%55$)2/<4F<#)F:CH"?76#'
@r9938
GAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTNTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATC
+
2E47.>'3=B8G&>*3.."*?:9+CA!F1ED>7H%&(.(H,$9.&F1->..B>3-;<2-.B"41-C!5=!+4:5?9>&:5-,>C9<G($H>3774)@<;1.G.$(9)+A)!!(?>:;=0?)/:@'1>1:=&E;4C0&/D#)?%FFA.:2EEF0;;4@&2./.1@!A+!AG#)EG%7)>HD4G9=,=3.=3B1GF.'(12H02(9D75,G((%7&6/1D+!!+6G
@r9939
GCATTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTGCTTCGCTTCGCGCGGGGTATCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCTGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACNNTCCCCTTCGTCTGNCGTGCTGATCTCCTGCGAAACCACGCG
+
!)"!+)&$)$)+%$"*%"$%)(("&+))#*'$&"'")($**%##+''%)#&&)#'!&)!!(&)"!+%(&!'$+&#+("$*####"$&&#%)$!%%%!++'"'#%"'*#&)&+!+$)'+$&)!!)+'&$*!%))$&)&)$)!((+('+&'#%"**&**$!+"'%&&$!%##'&%)%!!%!%&*&)!!+)"#*(%*)&#&*'%+"")!!'"*$&$("&&'#'$&*#*+"'
@r9940
GGACGCACAGCGCGAAGGCATTAACGCCNTACAAATAAACAATCCAATGGGTGACG
+
9"23))<G;E$4;)C6$E7='#),>?&%B!/4"49;-/&(HAB3;$1B+-G1/2AG
@r9941
GCCGGGAAGAAGNATCCGTTACCGCCGGACTNCCAAACGTCAGCGAGCTGGTTGATATGGTTTACG
+
6:.>B'-==8)%((/E/(5B8,<'0B+;=#++4;G*<=G2.@G9)<83>-'1.'==<4CG(C>061
@r9942
CACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGNACTGCATATNGATGCTCTCGGAATATCAATGAAGGAAACACT
+
4!99%'7*+#4$9!?*E:#!5"3B38>+"%*4!=(@;@9B$EA::*$>".)#'1!AG+-.,$0)2#7&?&4/?4(G7,-3=5C!FGAF#)C75>=%!A?1F7/A/$*9/.@'+$;;9,6:(DD</=?D5+"0.A=>-7AB>3C4!>+,5!D00!#4A)>6,<(2'$148=F7$+>B%(C)$=D$""*F')7GG
@r9943
ANGNNCNANGCGNGGNNNNNTNGNGNGGTTTNNTANCAANNNNNNN
+
!!"""!$""$#$!"#!#""##"#"$""!$##""!!!##!##!!"$!
@r9944
AATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGG
+
5>%/*A5DD?G(680+54BD*?21+3"==B+7/7F4#0C?"-B;/%<!F53;A5G3G>$)"+@;+1DF,H5+/2,A=@A$F+4FB6*21$&HG$>=
@r9945
ATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATANANCATTGTAACAAAGGAATAGTCATT
+
38G9>?."F27"<2"4,40081#&B,66;7>E1H%E:>+.5?#70)*1()*:3&&/1'/$%9##)/,?5?>H=7DBH61)4.-
@r9946
CTGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAG
+
)')+$+$+('(%)**&+')##!!!+#("%)!)"%+*+$)(%"#+*"+*!(+
@r9947
GCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTT
+
C)GF)EH8C.09BD?@;8+:7<.#<;'9->$29.=.:=$*,!D:69<:)2?>#H,'?4GB<1CA;?>.D-;*"A6E<@)B#$3(*H4"DE'
@r9948
TCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAANATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCACATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACA
+
2(-#-"@=1-2/!'@3$:&#1)$/@,/#-D3GE-;-,BE=0;+/$78GH12!2:5543"278>H$"0:1(5#%HA)+H>>>/);?'@H$(<HH",6#@1E<;):F7G$%8B-812$?EE'&@6BCDG:DC$0?!2;B6>><-+3@:93(G9,/.&
@r9949
TCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGNGAC
+
5:/0'C++#A!"%!3.HB(3;7)>"/75+?+B&)<8?0=$'",,&27B;E7=6
@r9950
GTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCTGCATG
+
47)33%DC2=HA1+#($EC7/B6*@,@07GC*BE9*,&@&*7$$9F>GF*BEG>>8F48<:5(*0C)$(<,,!9<E/B+
@r9951
AAACTGTTGTTGATTGAGTCTCTTTGGTNATTCGCCCTCCT
+
*+#(#+'("'(%"$%)(#!+**%*!%#%%!()&$"!"))!)
@r9952
GNAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCNNTG
+
#%3:3:*6324D'1..5.(%5)+9&5G-9)6$0"8H9@#"6=@!:E)>/DE&85!>!HD.3B"":G=7E#D%$13HC6*678%>,1)79:AG8=.#CD:2G7:&:8!),E"4!GA2;'H+?.3(-$D55!@7@"9<74!/)56F'/;#54=%F5)6!85>@B0-*=(#F(FG34FDC>/'5
@r9953
NTGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAAC
+
'.%!"H/44%%$,<.97<2849'-.;5H>F6A>78!!<&)%5$;33@*DA;!$+)1!9:5A/,D(E4;'(=,;/<82+%7C=F%.8!.0=1".
@r9954
TCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGA
+
17@2$#H40D-F1"#)5&>B93(<B&GG4G:EGG.($A*#!?:F=)A%C%!B!.)-(9(F
@r9955
AACGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCNCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATNAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCT
+
BD0*51%+!;CE;D.EF64,#='+:C?.#'8+;(0-B%H,.$(>(+)/,8BCCC-33#:E5;@281:46$0374.?/'8&,8E-(8<"&H!*C67*3>2EH,8<':FHF%C:-2*#5*8!<GG"/?$>>=AH@B?2:HGA1=DD?0F+;49--G5;@F"*@"F&)'8A%=H87(;H4;0:")8!%@8+0<&6C-5!F>G$#D6=-66-!2C81'B41-@*G?F4%23+9B7:?)A/AGE+EB?-G!-+EF/&?CDC)".<>"(<D"3>8#2A'?!/>-*90,;85+4?H**<6<(%@!9E,'C3@G#'0=2D(@*G0$%)5>03%!9)E@,),/
@r9956
TTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGATCCACGCCGGCCGGTGAGAATTCGGCCTTGCCGGCATTCACAGTCTAAATC
+
'-@C(:%7.631)0<#?A6.'F0C9+!:54?."53D!==*5-@0CC<E"4>-%39-(+'(.<H<0C1HB5@4H+#-BA:4FB99',(E7B-"A'6
@r9957
CNGNTGGTTNACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGNTTTAATGCTGCGGTAAA
+
'(*$&'+$$(!$'*&(&$("#*#%#'"+$**(+"""$$%+&*%#!$()$)*''+((%!'%'"$&+%()#&$#*))&!$(%%&(
@r9958
AACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCANGTCAAATAATCAATT
+
)%56=8@;4+?H5;?/>?EB924;7-4:*5#D"2/7%F#&*=*:=+27.67:+0?#G+;'";D7,G><%GD%#2DC,4-9<>3$<>C9B"9A%%;);&4!7%-./'5?,D?#:GC#2:-/;$<E@C9*%87"9G1#2)9=+,3B:*=7G)!2?*'%B?F'!D=8(919D-6AF&D9@):1/'2,5?":05D
@r9959
GNNCCGCTCNCNTTTCCNTANNTGNTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAAGGTGCGCNGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGG
+
"#)&#!*&)!(!%)(%&(&)#$("("'(''(++%%&)*$$!!+"($#!"!&"!&*$(!%$&))!"&*)(*+'!"+##$$"+"!+"*$!%*%&*%%"#))"'""!#'!(#(')$"+++"))&%)"")"(+)!"+)+#(+%('&*"%%*'!(&#((%%#"+&($*
@r9960
GCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTNTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATCATNCTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACA
+
(>77%&?"94<CFA-5&:$<6/)B.,)F7F?F-2<(*<=@6#83H%?<(?!B4C1@79F"@#+"/#%A3*..7.B5@&E"C2*'D#9DB<"G>:,/+9/;=0A3-%0:@:10*=189:H0D0$&E"9D:*F5?5=5E4.B*-*A=&-4G5H<!B*:8+/>/$+9,>4#&'*2GF(#A43>7A#.?.9!(.F!3*<>/,4/C(#%F5&G*".@<
@r9961
TATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGAT
+
8B#2+HG.3")8B9.#6;*G7:*4'G=9B;%,H,@%'="@'8D53C.#51D"<$4
@r9962
NTCCTCCCCGCAATGCGGGCAGGCANCATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTNACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTNAACACGCTTGTCANCCAGGAACGTCGGAGAGCCTTCCT
+
%/,666?.?%.%0<6E>.<3'2.H0$*<H6)#!?4'$&'$HB,*$5GC*-B)<&+;=%1!%*FH,G2/+14<-@-1;<E7+,69=,;83&8B"'')#G"39D1;5>D,*':7?GG&7C-'EE82%-3)/H#H&8D62-=46(E;)31@EA4'#;#F)DBC?;+AC8.=)H(C>
@r9963
GNCGGTAANGATTAACAGCCCATGACAGGCAGACGATNATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGT
+
#!4*D8+2A?/%#8(H+-7A#$'+F&0F-%!AG,$+?0+6!#/8")2#"216<1:=,$H5,$B/B+.!/4%)@9/C4;:!$B)>;(%F5*<",'0$'B@=GF)'E.(!G(A#>F(3!3#8).//4&4.="!$5!&<$1D70)-)4D&?<@%#>18)"=)HBD=F<6B''E6.E+/<"#
@r9964
CCACNGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGANANGGCTGATACTGTCGCCNCTGCCAGGTGACCGGCNCACCT
+
%+$'%&%$%!)!#'*'""*(%'""!%(*!$(*+')(!+!&!)&&'#+"*#$#"!'''*"''%&*#'"%(%$'+$""$$#+'%+')%""()!%+'#+'+%)((!++#$!&%"%'%%)+#))!&*++!#"*+%'%!((*$"#'"%'"&(*%&!%$'+%(!#"('(!!"&$(+&#"(!"
@r9965
CNATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATANTTAAAACGATGCA
+
&#"'+$&#+'%&*")+"#'%#!*#&+*$!&"$%%++"*(&$*)!!"(%'&')'%!'''&&%+)$'
@r9966
GNCCAAGAGACGCCGTTTGGCCTCAAGNGGACGCCGGATGACCCCTCC
+
#"(!"#+%#*$)+%!&#%(!%#%%"$)%'"&+''%&&*")#**%%')'
@r9967
CGGGCGGTAAATGCGTGGGGGCAGCAGNGCGATCCGGCGTCGGNATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGANGCCGGGCTATTTTTAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGG
+
*DH3:A$9@?5#<H-:1-=$)4-)F9/(=199948&8;581?0-3.A%8"?3?H/,,%4=@!,31A7')<.G'H4F5G8F+,#A1:=7CC"<,,1*#0;>8.<49(7#F6=5$+##+;GH79&.!7=4700%1:0/$9!,H;;,?)H#
@r9968
TGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCAATATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCCGATATGGACACGCCCGGCGGGATGGTGGCGG
+
)D0@<@'&0.14:,!8''+E46<G<-9/&H;55<""FF#0+"#1-=0/82&HC$!95@'G6?E+:5F3@B'@*B#7E.<A(.EBE+6,.4E<%>+<D61H$H%+&@4+%#;;B&C.3E;)>18HBF/;B@*1=+-$:HF12,2F&)%B9.C.?A/+B"@-9
@r9969
NTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTTGCCAAGAGAGTTACGGCAGTTATAAATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGNAATAAACTCAATGTCATTTTCTTCAATG
+
$+&''$'!'!%((&&')!)!$&$)'!#()$!))"+%$"%*'#%%$+&'(#%'()(%%($$!+***)*#&*&!+"(#+)'!($#!(&&'&*!(#&)'*$+##$*#!'++'''+)*'*%)%#%#))#$"$#!*&+*$*("'$!+&+*)&*)$)!#!((*$(!$$')+$!($*$"!&+&)*"(*()')$*#(""$'((++!($!'('&&!(*")#$)*+"+&)#'*&)#)#+*$$&&*+&%$+"$$('%!('&&#'#+#+(&)(%*($((!+""$*'#+++%'+')#"(#"
@r9970
TTCTCCTGGTCGCGGCGTCTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTC
+
11+%&A*C466*A;D".6'(#G+'"2-#@5>G=-B-?7A*'0"!0$5/@!;:@&&E2&0)9;:HHCE($2+0CC:;-,3A@!='4')A6'?.5C+AC-AB*;G=@3C,C6*9/;&/"?CCD"'C;./!E*G*79D1&09$A,(
@r9971
TAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTT
+
>3?45$G-(ABE4"4358,1F'C3'<4,C?HDC59!1@#!=C$(@1.F+2<4&E
@r9972
ACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACA
+
@?&4E@)/D)><'%A*B)<;B>$0C)7-9-9??<5*"*?#;</G)"4)31AC6ED&<7+/H'8')20/
@r9973
TGACCTCAGAACTCCATCTGAATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTG
+
G#3366*%?'D%@1'+$;-6&0."/:3,"G-FA-*/B=&:"/>A9B98+:27+07@A@H&1/)?<*
@r9974
GAGAGTGAGATCCGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCNTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGAT
+
@FC7F)77?,?==&C=04>DHB2:+D21$H-E71"+*@B%2;HH8)6F'EBB+A23'&F8.9<&+!3&-/BEG/)<G:1?::-8$%#)$$@>G
@r9975
ANAAAGTAGGCCTNAACACCCAGCAGCATTTTGNAATAACCGACACGGGCAGACTTCACCACATTCACCTCA
+
%"+"*(*!%&#&&"(%++&&*&$#***#(#)*&&*(#"$&*+&!'(*"&&%++'''#+*!&$()#'*!%$$!
@r9976
NGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTC
+
!289-$:7?>!#5A&&G98$47,<7G*6%+&7="#9DD8D17$!$6E1(A58!3H47)
@r9977
TTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAA
+
B*5)>C)3(&(@+2A0$0*E?$(1.10;*C<5A64#</H8&<8//FH7!7,>,#'569)89"63'&030/;*2%E8,);#C3%"E/GH79A<@1D:0&'0:".1:67A+C/H#4G44*F88*
@r9978
CGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCC
+
C6&#C9C='AB=B#0'9H9.:F##FC3#C"A!;(84@17+<'A&%8'B//6:H!,,G?GB*7FH52-4::7BD:D?E1#25A!35F&4!,?":>/F'7,G">*,!(.(H>%>*"D-E>&3E5?G4"
@r9979
CCGATNANCCTCNTAANCTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACG
+
(%***(&!(")%#!')$*+&%+)&"%$#!)'&$+$&"#$$)'("&)&$&%+$*)*+'&&')
@r9980
CATGTAATAATTGGTAATCTTTTAGCGTATTAGCNACCCATAGTCTTTCTGATATAATAATAGATGATTCAGTTAAATA
+
E+B!1''9"=!3)9+A23GE/+3A$26)FD.C2H>3#27)&G!C2!,'#/&H>="0?D-@"59*@!90</H1;$48FF"
@r9981
CGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTG
+
@?)0#9?'264:15C7D'?D4'5;+'2GB:!A"3H)B.?%A!%5G
@r9982
AAATGGCAACCTGAGCCCTTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTANCGTTTTTATCG
+
?%$9=$B>F?%A0=8%-+"@-1>,"#6.;8&$"F89*G590*C%D%C62@@"AH+593:244=F("-28$0)@0*
@r9983
NATCGCAGCAACTTGTCGCNCCAATCGAGCCATGTCGTCGTCATCGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCAC
+
+("$#$&#+*+$&"'%&"')*()"#$(&!"$!'("+!$+"&!!!%('(&$""!)'%!''$&*"**"*%!!($(('+)!$++"!%''#+!#+%''&'&&!&$")*%$
@r9984
TTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGGGCCNGTAGCTCCCTGATGATTCTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGAT
+
16#,F-&<G>):#-*;9!=1+=@$0A,-G&75H<%H&"G9)@=*3B:;!$%;F,C>+>63A(9/8<C=AA/7>>!3<=F/1&('8=D'&#?4C.#2A;868F320=G#2'80*
@r9985
NCNNGNGNNTNANGNTCCAGCGTGAAAGCATTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGA
+
#$&$$#&!$%(($)"#$'+"+$&(!&'#$)+"("*)$&*%!)!**+%!'&#!#!**'')$)))*$!%$('(%$)'$!)*(*&##%#+&*#**%*%*$%$&"&)))'%!*+%(*$
@r9986
TCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGNTGTTCGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGGCG
+
4D<6-11<1D3/3.%')+C754#2)$##5,.E423@DBC1-57/$)2"<G(,!(#=<$$2E1!=06;EH+(..EG@E#H'+%(G05)$6,+E/87A>'B$A60!*>10,$7*(DF2-=')G&@9,%G="$;+2:D/&0>4=;)H%/+-0-40&>#HE,F?,:'1=/4=D;@'A'..D&G93CA15<$%0#@&?4*6;C3)F!6!/+!D@.46<=>@')%11D:+)D6-A"A*6=(8C7??1
@r9987
AATACATTTAGTTANACTTNCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTA
+
'#)&#*!((&"&!)!&(*($*#$#+*!&##('$#*&"&#)#(+++*%)+*!!"$&%!($$(#
@r9988
GGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAAGAACCGAAGCATGCGACACTGACGGCGCTGGCAGGGT
+
#+&+&#'#"#!$#$$&(((+*'#&!$'#$+%*!+'#+'&'&!!"%+!+&!#%("))+&$**#!%'')+#)"&(+"&#&+&+&()%#*%
@r9989
ATTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATANCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCGAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGNACACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTT
+
'!9(.9/E(+$5#:(H08=36%E74.$@4"".F,01/8E&,')09$8#A88+?9;0<!<;%G9H#3+C#$<%*1>>+%3,(D',$GEH@&+),A:E1;C&">7HB!1@5C.48$6*5)%-+!+@*16!-<(81!'49HC2B<3C*#?'0!A)?+>8<?70:=>D:E7"%FE:/)42+E)%@8'$-/4<E5,&18*=+,1+.;:-
@r9990
ATTTTAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGNTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTNCAGGGATTAATGAAAGATGGCAGACATCATTGATTNAGCATCAGATATAGAAGAATTACCAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGC
+
A*&G%4(H&8&C8++5H5E;"=37"%<A&E7F*D(5,E;7;<.?9#>,?&D/9.+D'(/>%FD02D(>59?-A<//37(>0<.D*/67&)$'=#?<C;#9>,3A?9&C98"@,6?4$DG9?*#4=@<0#0$;'3D/1F9:2H9C9=GG0(.2?C@H&<#0$)CD,-,8=%1$G=C;B/94(3;6DD#5,GG?7)9/8!/;D#2CE'$=$1D0A"D*E&'A)=4.1>0?"9//*!?
@r9991
GATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAG
+
+3.D0=H.A8?&)%8%1A!833E:<6<>;;H;&$A!/6#=-F&>C4<22)&9@=A>H%/?B;57@<3%G69%=0"%;"A2-943<C.3<%<4C4!61?/95B$B<H
@r9992
NNNCATCATCNGTTCNTGAACTTCTTTCAGACCATCGATGGCCNTACGACCGGAGCCTATCCAGTCGCAGCTCCCCCAGGCACTGC
+
%$&')%%%"(#!'*'"'"$"+*)*('"%)$'*(*%$$$+*#$+$$!"#&#*#"'!'%)#$!$(&&""&$"%)%*")"!!''(%"*!
@r9993
GGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGNACAGTGGTATGACCATCACCGTNAANGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGT
+
<<'(-<GA9%''%4E().H5B:*%27G!A:7C:'".;E$4:';)E5&.D0*CD/8!=5*9'1D:E>(;<$')95*+9A4##7)@(.*07"*B59D,$88(+$019-15!FCC&3,C3/#(%.@'442*#B=%0G/8
@r9994
NCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCAT
+
#.,$!B:8<H'AE6'B80,6<8?@DG""943,1?,"8+B1#,'(<)4-*9?<93/90>+/99=-@F.@:7FF(59?F".)(/+1H+,<698%<H%(
@r9995
ACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCNGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCG
+
1.)CB;E5!*.6F=,(>F+7H5=97H0!E(4""(%3(E56?!C("0@HF"="=/1189973AF2H$C9!2433#H,1C.?".#@7-=G!/<%!F*=8-/@2/>H4"?BBA>E*7@A>358!"2/+5C$))C+3/=/6>-=0<:&*,B3%(7BF+0A&'*;/G1
@r9996
AGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCAC
+
;4+3B2#A,"%&;.30&C:,.#74%6'72#8-.8'+@<7*A0H-.0-:A3?<//--FB-(:H7@>DB=GC549+*;1":'!E>#4/F/>!;.D?#*
@r9997
GGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTT
+
$AB-8?5C.G(B9H(96=+&48D01!>FE3GB+:.FCE#<>B
@r9998
ACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGNGAGTGGCAGCGACATGGNTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTAT
+
<HB3:@$-7E"662+#D%0!12CFGGA&A&E>E()-'<($ABD6":'1B!=AB&B<1:6$/4*/()(@G(9701!0B15HGC.D"2(:+,<)6?@7;65%"H$,;A11B#'C+#";BCFDD0=::)CC67:A>$*"#:-&;(*?D2*(/8%E/>-D2=.4H)CC&*/A5<"!1'+-)":G?:8BCE!!"/A@94:3H3/&?G,4/2-%=-6370'/C!/-'>B7A:G49!C%=8:'14:)!H+@)
@r9999
TTCNTCGNTNTTGATGGACTCCTCCACAGAGAAACNATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCACCAGCAGCATCAGCGGTGCTGACTGACTCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTNCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAANAAAGGAAACGACANGTGCTGAAAGCNAGGCTTTTTGGCCTCT
+
()"('$$!%$#(+")$"&%('+#"&#&#$$$#**#+&$&#)!*$$%")#(*+""'"!%(#*$%+"$+$*+%(#'(+%$#*)%#+!"%&*"(*%'%"'*$*)'*')'&#("$!$(*)+%$)!'$'+))'(#)+"!)"&(""%'+&%#'&)"'#&#*$+%&")!*'%!&#!#*+(#$*'%&&)"+#$***"*+!("*++#*&%"$"$'+()&#!!"$"&+%#*+"!#(+)"!#!!(!*&%%)%+!'))+'&'#)(!+*!"#+%!($*&%+!('+)"+%#($!++!(+"('"$%"&*&#((''$)+("!("##(&+%+&)!'#+$("$&%#'&("
@r10000
CAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCA
+
+*#'$#)(#'"'!#((!*&!%"&#*"$$$*#!$()+&%'')#()*(+))*$*)$)%%*+&!+*)"$'+!"&%!$!'*)+(!+(+)"#&+)''+'%