view test-data/samples/sample1/sample1_2.fastq @ 19:4bb7e4a360bc

planemo upload commit 7f6183b769772449fbcee903686b8d5ec5b7439f-dirty
author jpayne
date Wed, 31 Jan 2018 12:38:03 -0500
parents eefdd97a6749
children
line wrap: on
line source
@r1
GTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGC
+
);A!/,6B:8=(*2GE1FGA>0/,?>),%.,/3+@D(C=<53!$H"HE-$79*HD?4<
@r2
TGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAANCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTAC
+
F*E;2#!93)*446F)3<FF#((G6B<E#D,4@=.-@<@/E59H,$1!D%+35#8#)&)9@A?AC%+-*!(C<!5@3+;4F?&A?=/4G#9&91.<,66!=#089'-(;16?
@r3
CNNNNCNATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACNCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAANGCACTGGCCTGGGGAAAACAGTACGAGNACGACGCCAGAACCCTGTTTNAATTCA
+
)""$&!#+$!)*"%(&'("(*)$+*%'&)($(!''!$"'*%&*#$&##))'!()")+)+'&)'$(##()#%###!('+#()*((&%'"'((&"))(#($!%)#*"&&$++*%"&))#'#!"!*)+")!%*++$")#$'(+&*!#%"(('$%$*)*+$%#!!+""#$**!%
@r4
ATNGGGNGTAATGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCA
+
()!$#)%&("#**+!()$"($%*''**+&((&+#&#!*$#'#%(''('%#!$"#"$'!&#)(%"$!&$%""#*%$#*!'&%&%$++###$"%)"##$!'*##'&*#'%'"!!#$'"*)#(!%+#)!()!'&$
@r5
CCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTTCTGACGTGTCAAGTACATCGCAAAGTCTCCGNAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTG
+
"(+,,3=$)%;3D.<!D#)4;;G5='E$B)D.*4D$-!G+?51')531:1",@D@<83+':85C8F?B?*A1;3G*%@16C*9B'?)HHFH)0'4+FE6F@<%@&>E49:!E86=ED=DA2/8?BC&6#<+%G
@r6
ATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGC
+
F65;?;0!43<5!0"332C4(3#)FE*>35HF@8#8?'C)6B5!7+"77&@/$>6H7
@r7
NAGNTTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGNACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAANTTCTGCAACCGCAGCAAACTCACCATTACCG
+
!''#"'"+'''*%&)*)!&(!)!%!+*"+!%%+!%$+'%#)+%!+((')%!''+$&!+%)&'&+%!$$))*($*&&"%(')+')+!")($('!*)+%'!"##!%#))""%&+$%''%*
@r8
CAGCGTCGCNTCATAATCCTTTTTCGCCGCCGCCATCAGCGTNTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCNCTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGT
+
#.1)<A;>()54A%D%)H",.!65,"3@/60@13B@8/53!,#3D%+;#B4+DG=&C"D,*=31*F@4C'0=C?,83+:9G'&@G?"31F9/3B9A@/(!!?;1>@063H=/(#D@3=*+BAF/*)
@r9
TTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGG
+
/EC(.EE4#,=G34#?-2#A7=539G7?88?+6E>8'*D3;8HH(H9A7<8<?"A'%4-(7->1%A6;@=?B@<,0%82C<<%-B*0&/H2"%##?)+(3H8?<=)@(><)D:<EC>#
@r10
TGGCATATTGCATGGTGTGCTCCTTATCTACACATACCGAAAAACGCCTCGAGTGAAGCGTTATTGGTANGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAATTATACCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGANCTCACACACAACANCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCG
+
E?;15/+:E.D691G8,1*<7#"6B5C3.9EG>@6B/:9<,4;@)!"'9.H!=;=.2/!!!>&H.+#>=B5C46(>%-2#66=;79B-!$14?/)'1++E:'-G<+3")7GG4>8+*2:/9&3;H6G:A52;(+E*'$-9@>;#GB?@.(@)*>A"G=08*="D64F/$$*/6F*11*3<4<:D59?3%:)&7!=7><,2>+-+!E%+G?@?9@7$**-<@!0,F29EH;1AADA(HF(C*:H>!1>H$)CC,023:;E>,&B'3*C,HG/H$%%2
@r11
TTTACTATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCANAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCANCACGGTTCANCAACACCCGATACTTCTTCCAGGCTTCCACCAACGAGGTNTCTTCCTTCGTTGCAATTTCCAGATCTGCAGC
+
?=2:=G&F/,C(!%G<A%&(81/=,!")DA!@<A=C-/H:)"!$2&2;5(</<.9A>"6+A*@=+&$(9>,85.&5!>7B2$%+BGFGFF)#?&F(?HE6B6E>B&83+(4E2GF)B'&2!*$=&3B55*)/7B08++F38/B%8++%-3&:H>79H:9<>)98DDBF<3A=@3AB&#*#5$-(D2.E)E<=*0"<="(1,#$),B
@r12
CATGCCGTAGCGCGGATGGGCCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACG
+
H3%$'!280C4"<<F!$B!7>&&75/,*B>7!.91"H32==8"A://<AGA<;B@5-<22:?"2@<;04+887""794003")1C=02D'*(<9B!F,2C%,6#>C.'%$/*9-42C="&DC$?46$.=**%5>-$%<*&+
@r13
CNCTCANNCNNGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCANCCTGCA
+
$##&&*"!(#$&(+)'$"+!#(%''&&)++"+&*(*"%#!")#$$(+'+!!*%$**!#$#
@r14
AAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGT
+
-/H17,6G3>'$<"H-$13BA90$BF%:D+H620<>;==8B9G0'@:8-&=DE7.6
@r15
CGACAATGCGCTCGGCTTCANCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGG
+
(+#!#')()(+($&)"+)&"$$'&%!(&('$))#"***+"#"(+(&$"+$'&%*'$'#(
@r16
CCTTACCTCTGATTTTGCNGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGNCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTT
+
=0!".3B<)B86>)6+G9A8,%/;566&A5DA9+D:+%:4A4>#F15222><2C>=);.*+$27:+/(/15&-(7E$5D9(8'$/:2B/A#:.9E,0'+E%E6)F+548C%EDE3%@8(<<+2.+@$H1:3;*-@'#BFF+7=+$+03#=-.8%=8/!9$(6$%-,+A//"2D;+3>7B(2=4/H3B5H,1/B""1>"'8D?9$E5&*(</8G1;-2'9.1,6<")0>6,"-+;6H,)D:),6)#)69=#?15#8<69"2%=//9(<=4$51%A";@G1=/#C3+C98C,*#!$E:$DD(+93D%(<:$%'/E6/D&;56=;0%
@r17
AAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGANTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGG
+
8B>60B'!7!G9"2+*!8,B3D<0;+E<F8$:?F,=@E-&<88D4G5.6<3'0?7!4>$GE60!>D+(%FB?5-3C+3,E?643/"-:'FAC::F09AC2D,'>F1
@r18
CCAANNATNNTCGTGCGGNNGNGNCATCGCCATTGCTCCCCAAATACNAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGNACGATCTCGT
+
(*%!*%%*$"#'($)"))!#(!'#(!')+%('"!%)"!(*%($('$(*#*!("'#+))'''"+"#')"(++('%"'($'%"'#+*(%%!)$"$#%$$"(#$$+)&%
@r19
GCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACGGGCCCGTGCCGTGGAGTA
+
AA81++B.3@,B4D06$D0(D(.@H,:5DG(F7BHGH=5#-1**19;!2>2.6DE$/4)3'3?;>8C1>&>.%./.H$/0
@r20
TATTAGTACTTGAAACGCTTNTTCAGAAGCCTGANGNGCTAATCGTTCGGCGATACTAT
+
0(769?)4;%F%=1<H0/("2=.;9>;-/+FD*E1)=3)-C28&0,06@8*B%70$*A'
@r21
NNTACGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGNTCCGCCTGCCAGGTATCGCTGTCCAGCT
+
$"+(&+"+$+!$"&(&!(+&(*#&"(#)"#$$))+(#(!))!&#!+"'"%"+)!)%(++$#++++%('"
@r22
AGTGTANCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGANTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGNTTTCCATNGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTACCTTTGGTGGTGTGTGGCAGTTGTAGNCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTAT
+
#(G-.'BE45)GD'(&9+B&7<87HGE6=7%!>-$*48/H>0(,)6DB#C:<=7"F2)'D,0A@6'/&9;3$)97$9E76)H&0!G9+%<7:E753,A%2C%*EB%98)64#GBH4F57((,",&!!$.70#@=&%1C,1*4D3!>))F%/,1!2%+&):CHD1B@EF9A:(7C75?"&5'7*!G?",?+/4B&$(6-D&#)A7%1<?=$+31!*!?%(.BE=<5#A/(4H)<25%<F?@E!:94)2$(1?#B*:A73:'+&*!%#,8!(@%(@&HH37?&?1CDH(?<=*#0)965)(&"@17GG.C17=4=/;2&@DGEF<;#,>-):)D545"+9*/=19)(9GB4%(8(:HCA,DE$8'0A-<;*&2B(1BB7B
@r23
AGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACA
+
'6/!@>,.#:2B.1H</F)3)?#?(2-(E9C=;;GEC,B:#+C@8E,?3D?6.#>>256%@+?E1;F@0'>35C7D43+25B9#G@=A+;
@r24
TGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTNTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGA
+
"CH,H<C=@FF.C3D9)>8G/8,A0E.EGH==&266-,FB:>8"H:<H%89<4(#9HG+2?>7D28(!/8H.:AF;7018H"'$$4ABB.EF8&"D;B&0DAD5A))A(8;C<E*0!;:+$-%C?<,/0EHD4F6,A9$2?G%!).H$,<*=)>H+=A2&;+/#(-+>%;'E7-196%.F0>:!5):=,-1C&7),A>2D8+%!.C=,<1=%F/*%HB1(-0GC-B5/;E;+3;AG"89B75.66$B;+<,=D6%7'8D",+'4;;=4+.A$/0<
@r25
CAGAGAANTAAGGAAAACAGACAGGTTTATTCAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAAT
+
;AB/*=.D6:>)'/A2E<,&F0H,)5'2F7<D*D*"!/4A&5D'G%;,7B*C*!.C18**5A!.>2#+C,,E%3,0&#$E6G!$+H4<$;8C(=F7?:
@r26
CACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCANACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATCTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCCGATTTCAATAACNTCGCCCGG
+
++;8##,&.5)&(8G"<.";3D0C%H2G8-A+=7=<.C#>5C2)H4CHC!H&#(DA!4(8*8.8F>#8+C*24(>%,DE6%:5&1"<A@4@$4"5>9)&=86G1'0-3%<5$.=FD)G->%>A,3*F-'D9?<F13#?6A!9=.,<3##&..''/;%%<H**!.A;D%"4.(9/;B*HG!@6;6);#2*G-,"'0;?/6":?-D;40-99"D!B0(/;>A2#.
@r27
ACTCGCGGTGCAAATGTGTTTTACNGCGTGATNGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCNATGGATTTTATTCTGGGCGCGAACAGTCTGGAGCAGCGGGAAAGGCTGACCCGCTGNATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTG
+
E&D4$6,&=F8-(7"4%C%#?!9%8A,AHG"/#B0=8:<H;)=,H/ABA=:5)E',.)23D4C/;H1+"8&??:%,.@';6,"*H(B;($!H)!-3,!D*C3".@&!>B&4;$96H*$6$'?5/2E21,<63G/-9)@(4*.+#)?3>%))49B)*&1G'E6/*@E'.5E'"C-ECA;;AG"(B$!D2!H8%><,73)H>C$'C2%9C@73>F@8$%(C8=C0GG>6!H52&@F>DE,5A?E:C@9%#B1.->*".D!*FB,)+.":&A6D,;>?:*$&
@r28
NTTCANTGNTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCG
+
"$"$*!)###+&+$%'%"$)&$*+#'))(%!+%&&)#&!&)
@r29
GCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGC
+
<'D7+"88F:%&@"(!%2*AF5)7<+&@<=#,A1@7438%
@r30
TACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGATGNGATAC
+
/*?+'+<2"@B'CF;>A)++<E7+G99&8!GE:0#G-))@7!)
@r31
TTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCG
+
3C5!<."-#>@:3,A)D*=;F=#>!@94*;(D0/-:'H#'$#G/0%;#'@1D18=*748F.:E
@r32
GTTTNCGTTCTTCTTCGTCATAACTTATTGTTTTTATTTAAAATACCCTCTGAA
+
*D-F,$HE$2(G"'<>1G)CD?70!.8(2G.->&C2<*5&EB;FB29%,:,6(4
@r33
GGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAG
+
FCD$AB"C-3)/)'=94H$*6,;/#0;B,"=;7/;8&'?"G)?C:29?2AE6&7#=28/H,#F6/,5+,!)*67E=A!5G#&3/:
@r34
NTGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATAT
+
!3-+9-G4,*+9;D71'-'-,,#E;8(D8(<HF3//'!!7DG9@C:$*2&/#:8!)"G-?A6
@r35
GCTGTATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTGAGCATAT
+
##*&$*&*+)+!('"'!%#())%'*((*'%**(#!!)%''"#'!'(%$%+
@r36
NCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACNATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCNTTCCGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAG
+
#*42E=<,;.>'=#4)$A+!@G.**(3'0&3=@(F9/F9</,'D75+6.>-FG3<+*$09*G%C-;5'-'9*"--'6GG$#4&#D9#C1%?C8,59$/2E&'EE46!?:0*&.+C=D"7G)$4D0E?C,1GB@8F*G@.H-,?-%;(@3*+5*=G10/1#:*'E02<@==CAH(<.;;8+&(7@BCEA.?)4=-<D.+:!#3F?D.;=@GA&'@=6C))D&
@r37
TCTCTGGAAGCATTCAGAGCAATTGAGGCAGCNTTGGTGNAGCACGATAATAATANGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTANTGCAATGCCCTCGTAATTAAGT
+
-/"''*%--##'4A.7?-*'8G#H(F;#6@1G"-EG"AB@>,?4*$8G-/41<G,$?!C7)4;<H4B?@!>8:,49'5>G@-E#)>?C')A&9C$?18HG:E@(#?2##%>$975<F8C?GB45DB"78C)AB6;#+2C4;4@<A5C?.E(<?#C!CD?'&@G&&4)+*+F2*@&H<2">(89H4@'/HD((9501/D&)!<9D
@r38
CAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCCAGCCGTAATTTGTGCCACTCATCATCCCCCTGTT
+
5H,;#A*">AC-/-.A::(!&"!@#$2-H+6>0$-501:+A*8',B6>/@+/'A'GE6$'*2++.A(:30?/8'61AF88-+0;<=H%/C.GEG,H7HA3,1
@r39
GGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGAC
+
),:@$*.<D2(@AE@,H4C&1=#3">@A.6))#927<8/B*9B8@,10C':/.)4;D2?#3-:9566?)3F#*%5335EF.$(!2EE
@r40
ATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACANCAGCGACGTGCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGNATATTCCCACCTCCGGTTAACGATGGAAG
+
'+1BE?+1(&FC"6#0=:+*&2B6+64)!1D"5+?8)(615<%1=:AB#1*40#+/#$2G"$,8AB6(@*,/'@7E27;8'%'2CA-7+8$C@(96<#)-?A0"=9>=;#9/(@.8<4.1*+8H%AB(%G''>)<:!+E&0,-,$C<$?@3),*@@
@r41
AGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGAC
+
>-<&G-68#469E5@,E@=FA%'H9;AG-DD&.DG-F(6.B71G?15%%)/6
@r42
TTCACGGACCTGCTGGGCAAANATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTAC
+
B?9"08@E,CDC'$,F%9)DAE?=+053'#,&/-747&:9,0E>75!0E"5GD1A6!($F46!291).>/*
@r43
TNATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTA
+
$#)+(%+%*(*&)$$*&%%))+!&'&+!!*!+('(")%&)%&%&"+(!($"*')*"%)$$('((
@r44
NAGGNNNANNNTNNCCANCNNNNNNTNTNNTCCNNGANGGTNTANNGCNNGCANTTAGANTNNANATNNNNTNAGTTATTTCNN
+
"$#!#"$!"$!!"!$#$"!!""!"!$!!"#!""#!$"!!!#!#"#!"!#$"!!$!#$!#!!$"$$"#$!$#$!$$!$"!#$"!$
@r45
GTTGCGTGGGATGGCACCACCGACGGTGCTGCNGTTGGCATTCTTGCGGTTGCTGC
+
<:C5".G4/,3F*6/:-E.<4F)+@6F)<&C3G'%=;,"$A:C7+#9/.;00:@/*
@r46
AAAAAACAGACTACAGAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTNAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCT
+
+(5'0?'&,+-098D2.<8A?G8;+E"D2,*:4-5C2D$>*"#%"(*.@)1!<G-'<53:>!7@F1=6%//(*7BG0=999,G+"$@(>!&+?!((/9@:3-6:/;F@<<0'1.:;(
@r47
GCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTNTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGA
+
=#*2)B27'9D@?<(D)!!99%D4#2)2A6.?'->.$6'.3.A?3$56$E(0:'8=0G$E(:#H>2G@&$2>"A34&"'=>4-!(AH8G$H5D:=1560225=+!:!%5"#D+:;41"*-*)17A!#17,#?!F#(3;7A,B4,.),%!)$,;@#-&86!=G$3=.&$:$=?;:$+?@9B)<7CG:7H7F,
@r48
TCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAA
+
*1B.?;9<1.21,HF;(E*<@!"E-3GHCC7-$"A.>2A8;2D/A@1:D;>20'9<64->:7C;/!<C+C+?6,<:64D(97/=$,''>4,>,A6=4*9-1<+;>,D$#?%4'A
@r49
TTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTNCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGTGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCAGCTTNTTCCTCGTGCATCGAGCTATTCGGATCGCTCCTCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCTCACGTTAAAGCTCGCTCG
+
695$1(G!4BF<F+/4<-@F624).83=53GG,%9977+HGF<%92"+(D+8!40B@0$=;8B:&G-B97B@+0-43@(6'B*H6F.=175("$8"7"!-!A(A)4!>#<2.!(:208G=D'E?;-F><66$A5/<<$:00;G<(0A:)FGE;1)/;)0"B39=@(*8>9F?+;#4G0C0/2,<=G@):",D<!0B$&35)+6'GD6H7D%2E-$#AGBC%*>:*/C2CH>/;4'90+/9A'CD($-G3.=%.A)78&%5<#B(9:@2E-2<0F'?"9+#9:F$*9
@r50
GCCGGAGCCACCCTTTCAGCATGGGGGGCAGCCATTGGGGCCGGTGGT
+
5@@F(C9-BCA%2;HH$?'"6$!7C;3!'E$<!&:&0DC%E:(4(#0,
@r51
TNAGAACGGNANTNGTNTCGNGTGANNNTNCNGCGTGTCCCNANNGGTTCNAATNAANNANNNC
+
$#"$##"!!"!!"""#!#$#!#""$!""#"$#$$!$$!"##"$$$#$#$$#"$"$"$##""!!#
@r52
TAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGA
+
9>/!?,;)C7AB'9#!:A4"0C?E85!@3E"03B@0*8'?2.6/"*%1AHB',7D>@)59-14?3)5B7F'912'.>63@B?F6:)
@r53
GTGCACCATGCAACATGAATAACANTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATNGAAAACTACAANACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAAC
+
+;(5-;3:%9$4(%59;?@A)9DE8#6AC6'"#911"#45>51;6GEC+'&+?>*0C;@CE;;D"<27A1>&4!BC"=B.11."2:>4C$/4H:!!9<?+59?"FG<,G5F1H=)-04
@r54
ATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGT
+
6C-#.H45%6:&!A3G=*!$#6@@G5-#27,,,"A;9CAA#
@r55
CCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTC
+
.#:D4&;+'@$)<0'-<(@%F4+*)''0<!/#0@(GH*/"<584:G15)-7-6.$E=8EH5"(90H3B%/@.H6E,+5.@&8$&=
@r56
TCAGCNCATTCGGNTTNACAGCGCAGTTACATGAGACTCTGCCTGNTGGCGCTGTAATTCATATTGTTCCCAGAGTCGCNGGGGCCAA
+
*"%&'!#!)#&)&")("()$+*$+#$)+"**%"$(&$&"((&')!%"%)#((&)#%"&*#'&&(#(%#+(('*'!!)"$#*'%!"!"*
@r57
CNGTNNCNANNAAGCCACGTANGCGAAACAAAAACGGGGTTTANCTTACCGAAATCGGTACGGATACCGCGAAAGAGGAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGAT
+
*&)($%$!)!!*!)+'$##'$"*&!$")&&+'+)%"*&%""&'!!%+#)!!)#(&)(#''(!+&$!!("$+)$!!!'')%!)+$))+&!&*%''+&+&*!("!)"(!(%"&)+#$*
@r58
CGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAAGAGCCCATGTTTTTNCGAGCGTTCATACACAATGGTGGGGTCAATCCCNCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGA
+
())"))&#!)+*%(+!")&*)(")($"('%'")*+$+*($*(&"&!)&++&(!('$$'%$"&("+&%)!$&')#"!&()(#)#))!(!)"!!+*"*'')(%")+&!(!"&(!++&$&$$*"')*)$&'##"!#$%(%*+('&&)'*%#(&")'!"!'++%%*###'
@r59
GACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGGNGTGAATGTCTGTTATGAGCGANGAGC
+
0+#0*/C72!>?3)>-"1$<@1&!'#&;*!6C=EEC.>$&#-7EF+:CA?.C;(7791E22#,F8%E2$!
@r60
NGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATANCGTAGATGGATATCTTTNTGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCT
+
$(!*&C5>C/+#=A<)+6A633E<AB:-7A@(?77=AD,>'>B'3F+76GB+>"@1,?<H>=9,"5:!.ED*4=#E6H#302G.6$'8654#BEG/-7=EB82+$2=/41EF2E96/4'(H;H,C@C!?H<*%H';9+<%)$,!0A8A#GEB'!A3&8BC$67"F8HA6E(*)FG9%,#:+-2*=)6:A4BB%/(=FC,)0#@#)11:9$:%.A(%"1%A@@&&FC5>=8F65A<9&<#;4.3()*B8$C1)EF'B58G%2?2B3?6#?4(;<B7@5C9&G*)%0<2F@#41<FH!-::EB>?:55#<7*A"4$%,.F508
@r61
TGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCC
+
20%0CG$'*1&C?CH5CH;<$2=@D0&A7$HG:%23@8C4:</#
@r62
NGCAACGAGTTGGTGATTTATGCGAAATGAAGTNGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCA
+
$=:391=AF+D<?E.!+,$%$6@+FH1%7B1,.&<E$)1590:<9?,02F@E#)C2;0;>.981(@2;B'A%A;EG;.2/8#&G459?-,95",#H5+C)+
@r63
TAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTNGAAAATTAAAC
+
B%'6&;!1,:4@.:*&9#"(7("0#8C""5(=:'+96?;0&H6!G7&*1$F<*<+D92HG"#=5B$H8@GGA6$&0./,56=:!:<H87%'F<@"E6$:$4.6)?)>!04.&!F=B*&3%?&1?
@r64
NGATGNANGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAA
+
%)')$###($+!((#$'"('($$(*!'&'&"+&%!$!$'&!'*&*&$$*#&*'
@r65
ATCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCG
+
''D:#+FHE)153,")-E*8D12(2;@?"$.5/@2'<8*:;/BH2*%06/,<@@=2&+)@"9B+HC@2.$"11?;7D</?%H+>
@r66
TCAAACATCGGGTTGAGTATCTTACTGTTTCNTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTAT
+
1#/,,4DGB>CG%D5+-*)":+"@>(>+CH3G079//"#H7"*)*/F%32/36=58'#9@!:G".#92<,>-+;C=</CA.<F--C$;C6296/5%?%<2
@r67
CNNCTNTTCGCGGACATNAGTCTNCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTT
+
'!*&'")#&)#)!""#"'$&#*'+#(+'*"+'#*("")(%''!(%(&(**#('%(*(+)
@r68
TTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTNGTGAGAATCGCAGCATCTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCACTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTC
+
9?D8.$G+<>#;AB(.=>H'1?-H<,#A.D+09$E0@A/.+-*3@#;C$(*!09@*;HCE)53C/=G'74#HC2'AC/)1#4DH$""540EF7&#>A!A8>!;0*@'H2'2/-.&$')+((55(+#A&)+&D,@,$$<@"/*5,*"A7,H3F64?==G?5.-1!H'DF67,H986/?7=>#&35$6#3)@<176:1=);D0H=3B)>15-%!055,,<'$7<EC@$H-=A5&;;/0>:4GC!12#(.=HAE%4!@$+"(>#>%49)BH%.H?.+>-"?4B@4G2)><&##GC-179)>8G<(G2=7D7@4.6$("<"7688H$1*1@?*(?EA:F682&"+6)>C+A8B9D)?G9%>=915:B">>3B>625)))7!,H*?C9A)'9*DC3-C,4CH-&HB;3=@#,3;%73>##DG4%1&6B.2-%6"7-*D7FG;+A!F2*F
@r69
GTNNCGCGAANNNNNNACCTNTCANTCNCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAANGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATNTCACNACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGCTCTAGCGGGTTTGTTTTTATCTCGGAGNTTATTTTCATAAAGCTTTTCTA
+
#&#%$$%*#&("#"$!&(''!#""&"+$)+"%++'"$##"#&""&!)$&&''!#&!!!))'+($%*!"&!*(%(!#%)&%#'+(##%*!()'!'%+")(!$)&((*"&("#&"($'+"!!&+)%&&&!+$*)%$"$!'#+"''!%"!%)"&+%&('*#+!#%(+'+$#&&&%%)+)#)"&))"*##"%!$"#$!'*(")(*%+"+%*&'%)')'%'%%++#*#%%"+#()!!"$)'$&'"
@r70
GTNATNTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGA
+
!%"&"$+&'+!!*%%""$(#+*(*!%"+)##$++$%$#*!'(!)#**!"*$*#$(($!
@r71
ANCCNCGTTAACCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTNAAAGAANGGGCATGAGCACCGATAACAACCGNATNCTGGTGCGCACCAATACCNACTGNATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCATCCAGAACTGTTCATNCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGAN
+
'!%'%((&'*#+%+++('(!&%!+%(+&"&")#*"!'%%+$%""!*')+(%*#!(!))'(%"!!#"+$(!*$$($%!)"($$+&!('%("#$%'#("'&%)#''+&"&"#$&)*+"*%#'&#&#(*"'()%*$!'&*(&)()#&!$#&!#&!('%+!)!%'!!&!"&"*'%&!%'+"&+%*)*")'*#*!$((&'$!!%&"*))'*)%$+!'&###%*!#('*&*!'"'#!%'#*#+#"%*)%*)!+'(&$*(%#(($!+"$$'%#%"#((&+(+#%&!)$''"')'&%!)%)))"$"'*)$!"!"(&$""$%!&)*#)(!&!!'+#!$!""!&)*$!*!$
@r72
TTGTTTTATGGAGATGATTAATGCACTTCCGAGTCACAGGAGAATGGAA
+
'+:613@!%-)FBHFC:),HA'0%--7@'F-E<B!8?7<)4/1-"9'2(
@r73
CCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGNTTTAGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGG
+
)B'56>1E77:1/23/#.":A!H"?,G-*9BC"3!$B?*3F17H"96E(#*;H!-785"C@';)%>:E2G,E'"8?+A1!B92%+7CB/%@A?0)7!$'>!F$3?24>A+6
@r74
TAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGT
+
?32B,>G=<#.-2-(@GG4G#H"C?31=B/'3BA*9+36(0H,>9H,?BA/$A281;%=&F8!E1(.8F>"
@r75
TNTGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCT
+
@<,-=B$-,5!;(64#E=8()B27#3&"3.816#'384?1:"&$<#2@/B;371
@r76
NNCNNTNNNGCATGCACNAANNNGTNGGCCNNNGNCGNCNTNCANCNNCACNAGGAACACNNNNTGNTANATTNCTTCNNNCTNACTNATNGNNNACNNNTNNGANGTNNNAACNGCNNNNAGNATNATNNCCGNGNANNGANCANCGACNNNNNANNANCATAGGNGNTGTTNCNCNACGATGNNGGCTNTNNANGCGNCCTNAAANGACAANGNANGTNTNNCNNGCNGNNGTNAGANNNTCTGAANANGCNCGNCCGTTNCGNNGCNNTTNNNNNNCAGNCNNNNNGGGGTACCGGGNNGNNNCNACNTNTNTGNATNCAGNCNGAGNNNGNGNGNNNNNAGNGCANNNANTANNNNNNANATANNNTNGNNCGCANANCNTGCNGCGAGCCACNGNNNNNTNANGNNNN
+
$$""!$!$"$!$$$$$""#"#$!!$"!!#!$!"#""#!$!"""$$""$###!#$#$##$#!!"""!!!##!"$#"$#$$"!#"##"$!#$!"!#!$"$$"#$"#"!!##"$#!$!##!"$"!$###$"#$!$$$####!!!$!#"#"$#"""!#!!#""!"$#"$#$!""!#$""###!#$#$"#"""$$"#!$!!!"#$$!"!!""!##"#"$"###$##!$"$#$""!$!#!!!#$"$!$!!$#!!!""$$##$"$$""$!$####!#!$"!!!"$!"##"#!!"$"##$"$$#"$$#!"$#!!$""#!"""!$#!$#$!$#""!!#$""##!"!$$"$$!###"!$$#!!##$!!""#$!!#!$"#!!$$$!"""!"#""!$$$"$#$!""!!"$$!!$!!"$#"$$"!#
@r77
GGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGT
+
C*'!<A,<0H&>:;F):-28!*-@3"6%*E/<,EA$#8D*?8
@r78
GCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCT
+
=$>(+6G"4+$0EC8@".)%:'1C7(7F@"@13C7GF."*/B/:DFC7C?B
@r79
AAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCAGGTTTGTTTTGAACAGTAAACGT
+
?88:>%CG'?;.C<?9)'$8%58E)38+%).9EA!F5"75(&?A$$C2"96.#+;</:(7,1(1#BCH3F
@r80
AGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGG
+
?E95&04F!-:D#.0:2:50&DH5=0E%956$%>FE.5.C*;>2&96?
@r81
TTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCANCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCAT
+
C2/!)DB0":=%AED?HE>!(-7?02:5B-BH:D/:5H09F!-F:BC&&4(EB!3H&&EG2>)9@/%0D<94%A6914&"5HGF83=E%8DHH1<,!"C">>&6;$-?%.:><"6A7*4?1@:+(AH*D!0(7,/;(:
@r82
GTAATGCGATGAACTGCGCATCGCTGGCATCACGTTTTAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAA
+
7B8/5D2-#E.A4*.A25<'+/(63F?=EG&H<-9%F%*G4(E'>9G*E<BC=.<,F!=0(,/,!H+8-F$CHC;8%=/H!#!?&'D"FHCC97)A"/=*%2<H4)0')C!,6@;&6)#C8D09$+.*=#6B(A#9/H"DHC"-'%CAGA7.3G(.>35;8G'1/>'!D"
@r83
CATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCA
+
0328E1&CEGA>D5*4:E(;'G'C(-G>47915+@,C51<C$0%(H2F8=!"*>&,0B69,H#,
@r84
GCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTT
+
G</AGBB9A"BHH+=E?"6;,%>D!6?1@66@-?G)1B$F;;#GG99;9G8
@r85
GTTGACTATACAGCCAAGCTTGCAGAAANGACTTTTTTAA
+
6@@F4=(+)7?:@86HF#G225G,A74$)332A=2&454/
@r86
CTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTG
+
C-::,#'+86(DG)-'H45.A5?11D'37*F!5##A)2:!#/(:&9F.$:*+!F(.@2$',4.*03!-6&.+6(*'
@r87
NCGTCGAACTATAACCCTCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACG
+
%>=BB8@3.,1$@"GHA>4231,;;$*CA/:-,0794"'&:42.5>*+1<.&?604,D'$),@,A132(3?E!?H:%(1;>%+&DE;4C$C!*48).=D")57F!!BCD!/8)8A1%+2D6!F77?(=1>>E&6D!2=GB.@A/%6,)A:+!F<>3"9,?FEAC#37D?:&36-)??2H9/8=DD>3>-'>+"(;!)>7BH3.(G7"4
@r88
GGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGG
+
32BH,/!!HE2==D>)E(DA!C,+!G+&+,5#:#1-@G6%;H69+#$
@r89
AACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGATGATATCCTCGCATGGTGGAAGCAACAACCATTTGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCANTA
+
%%1%<AE)0CH@)B".8.:9/<%>9FA*2%B1E?=7BDC/5=;E@7(D2C=1:.;C">':229;BH*#!4.*$2.-GG<#?DF?D1(8BAB-14B0,'%9:D&9CA&E-.1>"<G%2*09"9#*%,E+"ED"2$%.G@C%5$>$:E32>/'8%A+4*F=A#A##4:(E:9(1"
@r90
NCCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATNCGGCG
+
#H10)'=1.51E:4()3H2>(/F5G>!!D/)-(.0E"&.)!A&"G#HF"D3&0C2/,B$214(CC';$-A2@)39;,:/7G%#0A
@r91
NANTNAGGTTCCTTTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTCACGCTTTCGTGGCCGCNGTGGAGGCAGACGTGGCGGCTG
+
!#!&("'"%#++)!'+'+(*!(*'%#*#&(''))"))"&$'"(*&"'*''#$!+'!)'(&$+%"*!'"+''!+)$)&!%)!$&$+++("")*%'
@r92
GCNNAGTTCNTTCGTNCNGCAGTCTCCAGCNATANGGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTAGGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTACNCAGAANACTGCGCCGGTATCGATATACATTCGGTTGGCAAACTTGAG
+
#*!)'%(*(()##!((*('()&#)&!'$!)$'&#&!+'&)%'&)(")&+"')&+$'!+'(""!##)%%)')%+)!+#$&))(%%''"#')))*(+$'(%(#'("*$%*"+'%!+)*""!&"*'+"#(%"$#+"+#&'*"%!')!!!$+$*!$*%!&!+$&'"&)))(+$**"+(+"+(+*'$#*&(%!)()$)"%"($!&'%!**')*!#&$%&*)(*%$#&!)(*(*$(!"*'"$'!+**"#!)%("!$*'++'**+)*&&"
@r93
GACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTNTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGNAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGG
+
'A6B8@54!1&DC.)C<94E$#4(G-.!7;6/343+'='?9&!=#!?<(,5<C.:,@=.3(4",=;D?0@97#57;@2%F;@'5=?<FC5>%9/$E1E0BF#AA52@$/D>7'%2<1!G%@;7!>!F?C$'.@<
@r94
TTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGANAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCA
+
6D:)'C/.H6'<7=<*!3#$)4F$<'@2'4HF+3C6;6DC&@B='.E&/":?:1#BB;+#;/=AG./"949%!)D."+;;.A'9$&E6@G?<H,B'GF
@r95
AGCGCGTAGGCTTCGATATCGTCGGTCGGGNCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGATTGCGTGATGTTATTCTCCTCACTGCGGCCCNTATCCACCTCANCCGGATCGAAGG
+
07-2!DA!03*-(">=?()(!C3D&7".''DE/@D%@$$/-#5E&./*1E0$"*F=9?@2$6-4"1.#=4'*931!B$21*2">-?@"3B1*(9;&*0-,,,?:>%)F-#>C2:73"@!B27++'!+$)%
@r96
GGGATTTTTTTATGTCGATNTACACAACCGCCCAACTGCTGGCGGCAAATGA
+
B3!B6>F&,:,F320<$3%0-1,3877=8<909=)E55@:1<BE>.?D9'@&
@r97
ATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTNACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATANGTTNGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCNCTGGGCATCAGCGTGGTCTGANTGTGTTACGGAGGTTCGTCCGG
+
*:5?$7;;0!C#$:)/(=.H?GD,@0$4,H*>88)91'9/.G(H-)B7E2.%G%;:;#.0"1B7E0<D/364:#:.2H?:&:5B@!!<+F!?76+,23&(071DG-F@=H<<@=E>7.?$=FBB+?3E"&4>$104=C)%-D"H%EHE?<A.9!G.2!+-93#&%C)
@r98
TCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTNGAATGGTTTTTACTGAGAACGTCATGCGGCCTCA
+
62<%5%1H7<H3F55?.(17(487+9(($1'6F-)?DE4);(.<C8)),0)@9C=1<:>-:9BE:'1-+4,""582!GC"D=5$
@r99
AGAGCGACTGGATTCCAAATTTCTCAATGCTGCTTGCTGTTNTTGAAT
+
?-(A#=7<B,#;A&3:C2(9C3;58&H6?5!#$"<H:=247;=,>!EF
@r100
CTAAGTACTGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTAGCCATACTACTAAATCCTGAA
+
0)GB>?;6G9;>/FDF';?)3*539A@)4+B5GF4>$8?$GD5A31*D28B0E'H+#>G%>9A866.E:**&2$6&
@r101
CGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATC
+
"2;%G#28)>)1B;296.",G&B@8$:5@?&,(=B#1,#*?7".@E8&4B4.1?A$!2*&3D'!
@r102
GCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCNTCCGCGATGAACCACGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCG
+
716;"3C.!>*4'G8)?5%4*7?83@FG*GAB4DE<=.,0:A*&(G281)9"+1$2(234@C8G#E%%9@G6A3!C4F#/=.$@+$+-.9>20=B3A1F*;.F7"E3,!680H&&68&6)-&
@r103
CATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGAT
+
7>=,;:.3C->G,:9&8(<52D*7''"!:46"#G'3F0FH@6EB?0(.G'
@r104
AGGAAACCATCACNCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGC
+
A/CF-""@@-F.8F?"0#7"9;"6D/!F.**3G+E*+#./;@30+-G/(&8C0@$G0?F<BFE/
@r105
AAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACG
+
1$/:A>4&'=%.0+9D=*''31F*G3D0'-&;'.2*8;!ED(;
@r106
NTTNGCCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGCACCTCAAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGT
+
!"&!%$+'#()+(!&&+)*)!$*$&&'(+&&$()#&)!(+#$"+#)"()&#&!*#*"'!+$&)!!!'&!**)($*$#+)''+%#+''"+(!$$')&&*')''"#!+%"%""
@r107
CATGACGAAAAACCATATTTCATGCGTTCNGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTC
+
-='G'B>/F:+17")B!2$?!..C%$7(&:<G)#-1,/8F:/:1*)!3E6+''01,8;>>*&%?G%F,D+28<BG<.C
@r108
NAGTGGTATTNATGTCAACACCGCCAGAGATAATTTATCACCGCA
+
%$<@H&C=#8FD4>G:*(?2%BB8FAE*22:=FF=D.9H@B@<;-
@r109
GCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGG
+
;/.,-F@?+!!'*'+822E0=*'G;+0#E-)AD0=$(),@@/:E)!>D$<B<B#8D7A3
@r110
CGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGC
+
<C(4D"5B+2$DH--46@5FB6<E'<#%$#$2>-<:1<,F670C%1+".F(FF4A#B#4$-/@#4@FFC=.#D1)--E-*@,@.EG/;+.A0/9<$((+,+;&.CAH#D+45)H+;#8;&,!0$!$&#0*?@!60+98=9@8@$-!.4;G3D2HE6;
@r111
CGAAAGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGG
+
?/=9534<1/5=(0&%GC/40E?%F$'91!95G/?''*=?1
@r112
GCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGC
+
+%*#!$+"%*&"'&(%*#%'&'*!&*"&%!('%"&###'$&$"#*'!*$)
@r113
ANNGCNGTNTNNCAGGTCAANNGNNNNTACANNTCNNTNGNTNNNNNNNTGNGANANNNGNANNNGNCNNTCNNGTAGAANGNNNTNNA
+
#"!!$$$#"#!#"#"#"$!##!$"""!##!#!$!#""#"!"!!"!"#!!$$!#"!##!#$$"$"!$$$!"###$!$#!"$"$#""!###
@r114
NGACTGTTNGATATATTCACTCAGCAACCCCGGTATCAGTNCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGA
+
1-@(1;$:/@45FB!H3:4>!!+!C86A8"8?6A5=A6(E8'CGA00429"#=;-H8=.?$GG/!@+/3D4F.<
@r115
AGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTT
+
>DA52(D407=>AE??05;%A7!:GG)>:F'B(4E2#<B5..;1-!:$>5*202B9",@E/G:4FA6:,F6;EB544-C81//H92H&!-9&#)5!0B**B>5H9%#%E))97>E;E078788?)FC,(!H060+DA.B+H=ADFA()6@EC"68C=-$<D050$B"6!*&$E.D<H/F96B$H?*-+C4+A?C-31#+5>DD39%H*D(@*=B)-;=>5(C8<(@8$/,G!<"/6:D8>$(3=GD&1&E%?C+(!2DA#@A?,><)E&=4"6$)B;(%6)3B4&*HF5
@r116
NGCGNCNNCGGAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCT
+
%)&'""$('()*%+(#")&(+('%(+$$*&&$'**)&&%&))!%&%+)!+#%$#+*&))%+*'#%+$
@r117
ANNNTGAGATANCNNGCGNAGNNGNTCTACNNNTNGCTNCNATNTNNCGNNCGNGNATCCGNGGNTNNNTCANGNNTTGACNNGNGNNNCNGNNACNATCNCCCNCGCGTNTTNCGNNCAACNCTTNGGNANGCNNNNNTNNGCGGNNNNTCNNNNTACGCGCNNANTNCNNNGNNNNGNNGGNGTGNNNANNNN
+
#$##$"!"$!"####$$$"""$!$$$"$!""!#!$$"#!#$!#!$!!$#$#"##""!"!$$""#""$!"$""!"$"!"!#$!"##$!"!$!$"""!!#!"!""!!###"#"$#!$#$$""$#"$$$#!$$!"##!$$$""!"$$!$!"#"!#!"!""!$$#$$!!#"#""!""$##"###"$"$#"$"!$!#$"!
@r118
CATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGCAACTTTGCCGGACAGGAGCGTAATGTGGCAGATNTCGATGATGGTTACGCCAGACT
+
%/(3@&C1$#031(F*7*=&&/0&6:=+&.<A+:6G??EH*"5#+/H,9B"=)=.4%H-6D91BF84E-611>;F1D2-;D/$<AB"?';*:%95HE:;
@r119
TAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTNCACCAATCATTCCATNCAAA
+
BED4#'F&;+C%8+E%F&",1B0.B!H/**,@A:A".>H<+47#E->B$2G%9(:+1D6D1=3'%3C.%*4/,-
@r120
CANGGATGTGGCGGAGATGACGGAGGATGACGTAATGCTGATCACAGTATCAGAAGGGATCGCAGCANGAGTCCGGTATGGC
+
'(!+!'%*'($&)#!""+"$$&('((*!$)%'#+('*)%&&'!*&%('&*&"('$#(''+))'$"$&#$*((#&'")*+&('
@r121
GGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTNAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGNGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACANGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACACCACAANCCCGCATCATCGTCGCGCCNGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTNAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCG
+
+'*$!#&*!%"+&#!$($##!(#'))+&(&#*(+)"%"&%'!&)+$)'"*!&%*!&'&&%'$#'*+!(##!&"!"$!$!'"*#+$"(%+''$!"$)+'+$"#%"!!!')!+%&")$)(&##'%)#*%"&$(*"#!+"'%)*($"(()!+$"(&%(!&$%%*&%$+)"+#&&!*"&''#$!$&$#'!'#!!$+"'$"(+#)$()'!+**")'*%((!)%($+)#"+""&%$"!$##+"&"&+$*&'++""$+$%"'"!)$!%#!'&"(%(!)(('#+*%##($*#))#"#++#*#"(#+%)$)"#'*'&'#!&*%'$'#!%'($"$$+%*('*"'#'!'%+))(+"!"$+!$"&"$'"&"$$"$+"'!#%##+"#!#))(#'$#(('&+"'$&!&#*!&+!*&#"*&$(%")$%"+'+'!(!$'++$"+**##$#$'"
@r122
CGTCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCG
+
9?D&:H!"B#$#4-+*0:E.#;A1;5+'$08%E0./33<'F'->?C'H%>3&#?+=G2*;-
@r123
GTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGC
+
<-A-0;D!=,'<E)5>F(%3,=.;!#(%1*>(2':F14/614;=96D28.932=G$5G<07*9GGA!2$#&,/B#B<H9,1.)1$<.="5B$%9'A<;$-/F-E83H
@r124
CAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGNCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGGGTTTCATTCC
+
7:4560=,AD<4:*4.G'"/%@0!!5%:<*H#:0!C#/G-<'+4=CG88H;8F@+7$+B)78'1//#G00$1&(";=3.:=:FD?<<)*%A:<8D*.7(B:H4<#$A4E)#6-,>9;E>0/8D$+@23<52.B=;*H
@r125
TAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTANAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTNTTTCGTCTCGTNGCTGGCAGCCTCCGGCCAGAGCACATCCT
+
=,:,,*09=6*.E@30@-!;C8,0;8:)*:5)-H&11G8A1C5B6=27(.&;%F*EB4)#BC-F3<@B?BHB,"G=D1:%@&?;ACB*%C;';+6<?H@F4".'18?-?G3'#:GAA('/4&>.'!9.+=8?435;+'B5@.>'<?,64DH'091(2&!4$.'<GHG=?#<&177='G8=E0C3(51G4(
@r126
CCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCA
+
"/6%%?*3(>7,1#"&<(.8%.E0>,/4.E9#)*F21$6$B"7:'!>?)/9<;:G8'%@$??+DCC=4:/303D;7H-<>4!"3*$;08$"8E6-FG0,1(:89$<@CH)#<3)
@r127
CCTAGAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCNTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTC
+
*'!"#+'%!'$%*((#)&$!*'##%%*')!!"")#!+"!#+(&$#!%%+!)+*'&+$&!+!%$#)&'%$$!$#*%*$"%+("%+$)'$$*'*!$+($'&%#))+&!&+"'*#&##*)"%#)%*+"!$%'**!'+!$+&&!"++%&(&))$%!$$+#%+"%*')*#$(%*+'#*!**++&"$)&$""#&!+')%$$%)**"*$)%*&
@r128
GTGATAGTAAATAAAACAATTGCATGTCCAGAGCTNATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTT
+
8<0:/81)@+3"G(H95,6.@B"(+;%!+D1A+0&,1)7%F$F.9+-7D*+1%8@#8!5H"G3"7'6-E:?$*D0!@=!H,E16'HE(&=9?-A<?9=F;=125+$B$+>7/531=)))4C3<A=$7&-!-C>9-=5<H::?*>;A$3EAA:FG$?.0%7?;*"&(1/+78:&'!ED$B-@@%+=.B7#FB-<!4?8<"(>7/+9>@'6F3122H*&?G12
@r129
TTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGNGCATTGCATA
+
(8/>>$9/;0",8%D49-F@+!5-':&+6"%?3&%*4C+CD>F.9'<D#=;>4E#:'E%8110"D&$'D&1<G2&E$.1!:.,2'B/6*/4@B,/=EF=/E@;8?:<$&?1G2!G5;>=<)%.A@&E)$?8DC)$*'#613)C42D04/9'96.!6'476'
@r130
ATCTCACCGGGCGGCGCTTTGNGCACGGTGTGACGGACTGTTACACACTGTTCCGGG
+
D?-A2+9$H/>=&"<H8$E'FGGB%?(>'24<0&A8.,'&*E0<8EB0*"3:"D@*E
@r131
ANCGGGTACGTTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGACAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCANAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCT
+
&!+$&$)*+%"&+)!*$%!*+)*"$+&(')+)$)'!$))))*&!)(+**!$('&*&%'*&#'()%'!('#'("$(#!))+(*!(#%"#!*##!+(%$%"!(%&&%&**"%%$*"'))%$()&%+%()+'*#**%)$#)%*%#(()$('&)&"!+")(++#%+$("+&*)*#*'#*##+##+"'
@r132
TGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACNGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTAGTGGTTCACACGGA
+
F+0/-(F//A0)($:893:D,#2?7>11FE/*<D-;9<')1&F6%H")'?6=+)6?F(3A6.82>-9$0?B&6,5;6D8*=G6.#D25G5))A>/D>&.$3,9&%2B.&@@)!=0=6<6A%A#&/,3"EE:H0%)F9:&HH$2$5=%"G:;D='5<'C3*0-,G("7G'2./G/:0/FF.G0!*=1'>/086999$';+=E&9/D-F>@:-67C;@/E:G+*671*.:E6?+<#&68"8#5,=C!)HC
@r133
AACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGACCGCCAACAACANGCCGGAACAGTNCGACGAAAAGCCGCAGGTACAGCAG
+
,9&@8,)=1&@;AC81-H!F2.5@?A+-H/0,0-9<=<D(D7,&9#B.029AC"C@/:6*?;#7E1,$,66)C=E1G+A3#5@H9+C-9,?:G)6+?/D
@r134
CGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGT
+
"8/%;<9<-)0B>:?17G;;>.+(@(D@:B=*8=DB;<6?#45)2-G#.E/<H+'4
@r135
CCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATAC
+
>"'C,FD'2=%,9'G=E"?%#%#<E"?88'*/AG.)929-*-$B:':%?$-H<9&4:4H>#D?$*.,/-E'D'F+34(@GC:?=7BAF&B/.5HB:-8+!G4.$3>F%&4E)-C6&&G0=@2#
@r136
ATATAANATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCTGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACCGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGNATGGAAGAG
+
F(C8'0.-#-+0.96,)'B$>DD<G.<6-H8+C2/-H,7$+5BG%%;D$@73,):!4#EH&;3HE'?$E426E"1,#'<'=2FBAD--<C<28D!H/=;BH?E%<?E+A&+0H%)"24&H;)$1,4C?+-G.H73>6'8+$$7'B7'D/6&<?G'&),')35D3H=F?C1>=>BA/3C<@F#&/"9H;HAE<%7.8<'E<$2!,=A<,F)--9/:*&.,97#,FA#4%/7*!%:=!639@.*@2>F$*7)<1BD-".<='5#GD4-!GG'C@!73+1?@074@&*/4H#(37&A6G-HH%E=$7)E!E&6.C3;7@2C!4;+F@>75%=148A9#2-3B'129C.@;-"'?%GF./?"$'/1#&"7'/H?>(&>/F.@&H-!>B?>!'%;;5+07C?EH?&D,#*H37
@r137
NTNTGTTCATATCCTCACAGATAAAAAATCGNCCTCACACTGGAGGGCAAAGAAGATT
+
""&4?0#>#@*&4BA/F-"?"'"@*,9-C??F1/&?FDH=#AA?3/B8#7+E>C7*+4
@r138
GCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGA
+
-(>%)5-'G5C0@5E!>BDE>BG68D%65()7+'.)@(5%+2?+1H%;,&1.&#8/C7,$B"-.-:)7
@r139
TCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACCTCCCGGAAAAACAGCG
+
/HE7#B*>$D0?18-EA,%C-,0"/7"E=/<=.-C$9*.=DHH-?61:+B,0$/<3?E-9
@r140
TTGNAATAATTCCTTACGTTATCGTAAGCATTCGCTATCTCCTTTTCCGCCACTACATTC
+
'#'&'+)"')*'&!#")*!%*!"$())'%#$"*#+&(&&#!)$%"*&+!$$$"*$!""'+
@r141
GTGACGCNTCANTTCNNCGGCGGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGT
+
(&(!)(&#&*)#!*)"%**$"!*)+##$!&"((%+$"&"(!!%%+($"'$!"&&#!)+''(!
@r142
GAACTGATTAGCCGCATCGGGCNGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAG
+
;=3:6$6A-*#/9@,E(4)7./C@:)C2+;+C7-AG7B?=026?//9&5(+B<'E+!8;/=8,)D<E2:-;6*/%5(H&+4BA0G)G=@?10"8+&C*F7<>
@r143
TTTTATNTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGANGAACCAGAGGTTCATCTGCATCCACCTTTGCTC
+
5CA:CB.C,1@4D#/9.7-8*G'8(B8A/5E3C;E5*.!C#*1@7>:?:=3)5&'!C>1@!1:B&&)B+-FD2%F3$3"%1.6=#@=)&=($H?/
@r144
ATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGT
+
C2F:(H64)C6A!(A4%6/3"5'C7=3*>&<?!<2!/,?$:"<>479:59(-
@r145
GATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGNCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCNGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAG
+
)4B/:>8"F/@F&>>+%/#,D4<'37.(-8>H:-'')2.H(@):;&9%8(98D8G(?9F7=2G=?1!1F5-,><;)>.)&B*;CG@1#<25*.3.'.E9H*;(*'/?4$31-,0A.4F@(+:7BE9"-%@E>5A!*)G!D0G7D+3EA37A00.*"(497+1$+<9,F(E)G-;(BF3.BFDF8/)'A0,-C@/@-F%".$!!7A'
@r146
CCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGNGTTCCGGCTNACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATCCCAGCAAATCCGAAGGCCCGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGNTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTANAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGTTTTTCATTGATGATGCGGGACCAGCCATCAANGCCCAGCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGC
+
?G6%=+1$G-1F"&;B!C>$(>=6/<&8%E#GA8;AD6*F+F47DD'B9<<!B+5:FH,A2*-)5)19BBA-8H"9BC3="E812"%3;,&DGF4+6B716'5/%/&3D@)6B%G:;)H#-"C65;1.H,)'*;-'=:!4=+%G/@A&58&D")-"C,?."8B4&=&>#+E.807,16?6.;7HH+)0+'1)61<('9'=%>&C1,@#8C<'2>#E"-(/(=.+.@=!,70(F2F?59>/AE*D.'!";A;>01;$):A1H'F.&$:#A+/0EEB)3@B##A4,%B03"6;:+"6%2E?06C@F(67":7-:283$5)&E%:F8@*C7D@,:%3E""&5.$'1H(;9.-H;(D4B'<="7/8AD$%E4:=);!E'*>2,=>E.3!#//,,$G6="8B<D<4?)9?>"'"&&*7*0-5?:G;(*!*$"B1.=*/FC#=/.D6,B46',<2>#:":47(EB%
@r147
TGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGG
+
!1=*E8E$1905"A4:*3.>AA<C&0?>$(7*(70?GE9"G73+2'004(8FD?8.&"?7*B6B"=A4+.?.$H.,./@
@r148
CGGTAGTAACTTGCTAACCAATTCCTNGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGG
+
3,533BE/1B%(HD.=BG=(.!*B5E=:6"F,G(<-<(%!=8"%8<>G1"3;)3*A*H=,G>+07"=%1#88+/BH3A96B-.>.>.0:.%8-)#81'#%EB17
@r149
CTGTTGATAGATCCAGTAATGACCTCNGAACTCCATCTGGATNTGTTCAGAACGNTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCNACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAAT
+
1H8>5DC@=1#8?##83,9-0FG5';@,80+.A/;'/6#G*"@93.CA$+&G2>?')<77:=9'$<-<)H!(3E<F)#7E.B!C0H,E8"1)F138*(BH?BH;%?G,"E10>H=3%DH912D$0=C;@<@B-7=!-F9@;8*+@<=$''((73G6B%!(3#:4/*$()%3!)=.03
@r150
NCGAGGTACCCTTTTNCGTCATNCATGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCA
+
)$$%"$*'#&(&%'"#"'**''!(%(+$'(%#"#*!#)#''($&!+$$*)*"**##*+$*#*!!')%#*%!!%$#'
@r151
AGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGCTCCCNCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACG
+
$B:?GE;H-9;7!556HG$>-H;G(/(A54+D!;E0!"0G&+(8*7):$+,';GB#802;62=$H'9%&F$793!B%<G%8>4D/&GA40G6G'*9:#/G&*%?-.,75BA*7.A42E3/3AG>E(F/(6="@;<A@C-E8
@r152
GCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTG
+
)9%19:?=-*514=-C76:>@H(G2490370%#>5"6E3FB6&17'6D"=:1'B:%-GDG:;1%>,C*/.!B;:/0E0,.7DD>.@<
@r153
GAAACGANAAAANCCACGGAATNGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCA
+
#'!((%")'$**#'((##!")("&*+*%")(#(%('+))&++&'#))!"*'))$"+()&"&#%*&")&'")(*""%"%%*$(&((')"'#+#**$((
@r154
CCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGNCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCAT
+
10!F2C%1F4<+9==89#4+72(>1E0$E3D7*"7;3&0D>A?&,:#4/2!00&#)C"2<'$!*2E='@@D0#'8EC@<=&7<9*0$%7/>E+H5&>F"H4'$E*:.#7;5H1
@r155
AGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACNGAGGAGGAGAAGAGT
+
@H3%826D/=-=@;<2B**))*D'E2HD/&+%3/'AE<!0(&1G*G<.%-1?*79CB=H64%#-880H2C"=;*=6612>?+%B'$?(A
@r156
NTTANNGNNTNCNCNNCNNNNNNNGNNNGNNCGNNNNANNANTNCANNNTNTCNACGNAAAANANNNCNTNCTNNNCNNCTNNTGNGNNCGTNTNACANANNGNTNNCNNNNGANNNANGNANNANNGCNACNGTGAGC
+
$#$$!!"#"$""!$!#!!"""!$"$"$#$#!#$##$"!"!$!"!###$$"#$$#$##!####!$!!"##"!$$#"#!#$""""#$!"!#"$!"#""$#""!!"!$!!##"!$#$!"##"##""#"!""$!!$!"!!""$
@r157
GNCTNACCACCNNNTANTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCC
+
*$(("'$%''&&%*(%#+")('#!%(+(**)!+%&!'!*##"!'"!(##*+'#!"*+*)*"%%%)!("%*#))#+$#'&))+&'%$&
@r158
TCGNTTNAGCTCCCGTNNTGANACGAAGGTCGATGCGGCGACCAAATCG
+
&'%&&#"()$"%&**"!&!"%!(%'+%*!+*'+*#&%")+&+#*#"*&)
@r159
ATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCNTT
+
13H2CB)4?$/'3:'*/<G'#:C"7H*6$84!@719<(1+F7#'G5-3-4B3H:-G,4:/7<2*@E
@r160
TGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCC
+
4EG*%:1?:;0+5A6?BA?(!-EH;H-A#!+1;@!*H7C($$?,(9&H:A
@r161
GCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATCACACGCAC
+
?AACH*9!37&!6)@>H7$09&,*>(A6&(<B84(77GG-3>#D%/DGA
@r162
CATTAACGCCTCTGCCCGTTACCCGAAAAACNGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTG
+
8>.D/#08!'4@(G@!*6'A:=D72&4&"GH:8.)<#'0=D,#;>?@>4*>,()84F)<:GG!EA1'9?!@GGAD49'40)FD(.963'7G(>7'F8A9AD!.H6D)
@r163
GGGTAAGACATGAAGATGCNAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGA
+
('6=0G%46C<A,18%;4%D9963-C/+0!F!BD(&%?3=@?)?70!2%(7F4++..,/$&<>9%+%%E8+CHC2'.7.(@3A=1E,16)+6!1C1"/5%4D+":3=AE!->:&
@r164
AGTCGCATCCNAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCG
+
H4F#E&"<5,1%!"/5FD$A736>GG7)E-E4-9E&/%32G1F8<>0>B-26
@r165
GCCNTNANCTNCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCA
+
**(!'!*"%(%*$++)$+!'(%()#$&)+)#$"&(#%+!*((#'*%$%')+$$(+"'+$(#($$(!#!%$&$'*+"'%)'%*'(+'(+&*%"+&&'+**#%$)*)
@r166
GTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGC
+
G#E5)!#$3?B!27$,8D)"H6)#%('#61H=<3A1+>4$3?E1B>@520;+-7D*!G,?=CEH6BG26.&'0#,3+;;A>D2-4>2?!;@7'*$2,'9H,8,#+21%#+=0"4543#:49B2*1?
@r167
GCCACCTTCTGCTCTGCGGATTTCTGTTTCAGGAATCCAAGAGCTTT
+
6D;4"3-H"49D5(#F89,>/?F,<<233)7<+*B@(%?-:9H/:!@
@r168
AATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACNTGAGCCATT
+
-:*3&*H2=).&/3,%">8,*>5@-,D;+$.A$9$H%2D'5;3=AB"H/,A9&@1*?>&*-*?<E&9!@B"$/EA*G23@#(,C:%G,F-*9@G?91B"B-.;FB:-48
@r169
GTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCA
+
//9E$,,/A=&#3.F;:)?A&8B,&/*"3GA96AA0%/)*C-8$2'"&:;-C1'+5C6;,9%:E06)FGB%+'!F@
@r170
AGGACGTTTCTATAAGATGCGTGTTTCTTGAGAANTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAATACAATTCACAGTCTAAATCTTTTCG
+
=0$=$H@53(=64@DD5=;:$1)%0=F;.!)&H97!2""!-7D=7)C4<."!G$!HA#$?;G@<F+A15DA4,';@F,F*3HE06+@7*#*B(>'!-A4A68?(8>1;*&>)G9.-(0B=!78=<0AD';4&9@#8$B<A@D:&-"%C(E*#=3*821)5"7>=4"8A,7;#(8@50&34A2A#31F.A(
@r171
ATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTT
+
C%A&4-:403(29+!'C(@:C>/,9,,+D&7#"D:'G/@=-!;A);99D9.7AD&9/"$)5-F=&.D4$"0/H"
@r172
ACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGGGGGCA
+
,0B=-"<'E7/<59FG8-B0?D2;/:$"4>3E90E6/0/-F0#:E#2%%6$=EEE6@!-*BC?(
@r173
AAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCTGAGTCACAGGAGAATG
+
@B:#;+B/E*?4'C2),=BC6!"(B7$A3@16A65DB%.2'F$0,:A*6=;A<8./60EC8-898/:,+++6).H;C)339?(+81<AC*,$<-,<D)B(0$E:3<E02FD!C)!&
@r174
GTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTG
+
///:?89#<D%E%!*=556D:..15-C:22!"0C5B#*$(A&F=59G(+&C"8B/73><C'%9H/?#/7-#-(9@3/944<-#&BF<=9=8%!B*&,&+?=E07:64,;@-8%HDAF'?F$=$C&:".:*C8E8<HF
@r175
GTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTNCGTGTTGACNATTTTACCTCTCGCGGGGTGATAATGGTTNCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTNAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATT
+
@)118G"(=;&!=F3G@@F6)%#<9G;;C:-5BGH>#2+;9@(""@0H,.E1!.9:9!#,82;9G*8,2B5#8..902+#'+4F!#A7$A=9G,/0%&%?BE.;64*,16/D)8#:@#0D%8(977;+'/#6!$<:/?/6'A0A0%+5HE?+)?52%B(>@D>FA"DA*,"=99*3>58$1)<711=@*!#"-('(A4.7??.EH<B/!E=6C!*-/B:1"%*@:8E:>:B:A92,4#AG5!-$:147)7--3FA70%#@D=:$%D.
@r176
AGAACTCAAACTGTACCGCATAAACGGCAAAATGCGGCGTGGCGGTT
+
%+#!&#))((''&&%**'%(("%%#++(!+"*$#(%'$%(*+%$'+$
@r177
NNCCTTTGNAGCANAGGNANCCANNNNNGGGGCCGGTGGTATGACC
+
'$*%&*(*$()')!"#)!#$&!#("'"++#!)$*%$&**!&$$'+'
@r178
TTTCCGGAGCGGGGCTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGAAGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTT
+
#5<"$FH-4@#E?CFC=*"&!G?"<:,%'AD/)":(<*4'D3E4H@*.HF@E/%:3$%!3#,<;FA9&096(1;),C',HF3FA?>>">0:
@r179
NTTGTTGTTCGCCATCCTGGGAAGNCTCCTGTTATCAAGCACTGCACTGGTGACCTGGNATAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTGGGAGGTCAATGGGTTCAGGATGCAGGTGANTATGTGCATATGATGTCTGACGCTGGC
+
#+#$%(*+)*""+$$%#&*($!*%)%&$(+')%"*('!*+"$&(+)'#+!++()'"!*+(+&*&"(")!!*##)*&&##(%"(!++&()"!)"#"!))&&''%+++!+(%&!)#$"+$#")"(#%)'$'')*&""("%%*!+*"&)*+"*'!!&*&'#&##+++'*#'%+%")**!"$$+(%)+%*#!!(%)
@r180
ACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTT
+
=H;%"6H3*1F>*C.5,$?5:'42)G(A&9-*64>?E'#(.99E)@*@.&3&77#*.)BE4$9/6<08+&.
@r181
NAACGTCAGAAACGAATGTTGCAGCGTCACAACAATCAGC
+
")>;%@%,,>*E/;+G2-!C6>'7<:3+%AD#E5!H>3")
@r182
CGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAAC
+
/3.8#*-)$>607%+).8"%"6+$69"688A:#+(CA2&!>#3#81FH6'**D9
@r183
CCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTT
+
D=7,.B4@B4D,1*+C@,!A+47.;8'F+"312!,6H;HGD/+0>G:$29566&"7=E/5;,1%61;<*
@r184
TAGTTCTACGGCACCTGCAGAATACGCCCGCGCAGATCATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCGGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTNGTTNTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATC
+
11&(,"#9%6F!7/."=G%<&<5G!3&@=#;2&D=46.@?F0<F8G"(,A<:?-=5)HA9&H?=(B"%;2C!$/"1$;H/7E1H5.9D)>64FG;>"'1,23((+E'*B%'*796@F(AGB"HG!-@:G>1")F=5*3BA96:G?<E<!0E#D0/F>D#BG$"/C>67,+DA:'&GA?EE*0"(CC4*C5:8*=$G(8:@3%.$C:5&+.G?A"+G<BC'>4E'8@,C$!<H?2G:9A$.,7C
@r185
AATAGCGNTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCT
+
<H7/%E%E'"E3DE5('68+%(!.H",>D("*<,5$!D0'@8*8'.E0)6;"?/4;#95B6*-5#>?ED05$<=84C!!%?/*E1E"%"G28D):$>;@;(!H4
@r186
CTGTCCAGTGGGCTTTTCTNTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCA
+
(?/5;"!G4@F3'/#&.=>EAA.6-C0<:4$/%,;6&&5E-#G("-DA@6FB#='##/4/$<??8>7:9/54DA
@r187
GTTACGGCCTTANTCCGTGGACGAAAGACANTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTC
+
""(+#&+!'($'+!%*#(&"()!*"")#+*$+"'(*#)*+'+(%(")'(*')$#%$(+"!%'#&"%")%%*(!'%%++(&!$"!!#&"%)%
@r188
NCTGATTTGTATTGTNTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGG
+
*>)@453;3366(!%!9)'4+DF'/0A")A8/9:3=!+2&4*1C)4;@C+'B1-@+D-4H/D!>@D+FF21==()8@<&1,.4+!8)1#3*A8%29-?H-G%/9)+"B"=:C3"B10(-B#&.,$<>9.#&'@1&?#3>@&A/<5@H6CCB9-D;B:B&H1H;%C12=:5/5=D.%2:
@r189
NNATCCAGTAGCTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTNGTCGTTTCTCCTCTGCTGCTTTTNCCGCTTTTTCGCGTTCTTTACT
+
#%=(0(6)EEB73F@@H1+B;.3B?/3,='<4008<$C7#?!$0A;157&'#+B?!3282;00G;3D(2(=#%C/44@6<B$A3?H%:A5FB.6$&'<;;.274A'H5.C"6G6<#0**1/
@r190
TCAGGCCACNTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCA
+
420'*A(3C=F(46&5%4)54$5/;*0D,#"(B2:,@.8/3@%+,A62G0H,':.9G$-*3+<(.!772(($;%66H3H?=>@%'"
@r191
TCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGATATGACAACCACGGAATGCATTTTTCTG
+
.G.H;D;5;A$E-<;;4)-<"65!;%#@2;/(0"$*10?>BAE.4C.3E#-#4$69(=="H$/,8:5H/F;512G?4,'-158
@r192
CCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTT
+
F@*&=0F,5"@:;0#A+8",).BB?F8$6?48DE10<:,!$3/
@r193
CACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTC
+
>H=C&C)!*)D6=C!$=)@;&0!+>,#!D!H*<ADE@-*BHA&(F3.8C0E@
@r194
CCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCC
+
9,4;'@A9B36)=.'28G50+(6&&:'%FDG8&F#8H"&==B!$=?7'&54537
@r195
TAATGGATCATTTTTCCATNTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATT
+
7+1,?65,F1B6&G!$0?=:?;$)!A32(2F/-24HH8$%+B3A?0+%#9C:'A'?15"D:B&<:5-5>5&<)1#F*#?H7*&+-B,=@'*C>A(73B4$C&;?'D+!/G.1H$%6@B!D5"H.?,64)
@r196
TTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGNTACATATT
+
$@)<-<9@&5535%4*)%'9FG7E8<'2E<A"F/8(7$9(!0BGG=
@r197
CGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACC
+
@0<E<?'22#7>3*-=<7*G@&!3$:<8&*>/9+0C%&3;'9#+D%A('B5%@34.A+70F14":%A%,(%"'*$3873'B02")"/9>@;&A69G;%-@46=6794H5G'1F!3/7574AE!(C+<==>>EG?2/$+@7+(<#=<?$B44+40&C"G/
@r198
CGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACC
+
*7)$/*.C#(17G@G;E)<>">"2"B'C($<7<$894!C>,
@r199
AGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCCATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTAT
+
C#5@B7F2-=-3EAEF1&11'3?4E:5:CB0D3'=>"7/F>:(/C@B$+&/DG)-A6,"<&B4F443:>&53/@;'6/D8D'&@/&&?!1,724+/A/,9/95E780A%D9
@r200
CCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATC
+
EH:2D;&6*)':,'824*0?0$$>?(::>,&13)<!%G,7H#B,80B%(D.6;G&F7B?/C0)D";A&='B-#(5'/F#FCE,A
@r201
TTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCC
+
.15'5@A@<&,A?46$E.4B=-:0%6,!)=*%(?>00C)'G(=>3?4G?-$1)!9D<:8D=6.++D?0H+?-0#6>,9)(
@r202
AACATATGCAGTCACTATGTATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGT
+
;?"*B:@B6CGA!(0)6D#=AC7$A@<.+<>/>1:&<&>8%689+H&7;?4-G?+#6=)'"$A7##@$)3(@@5')A$!/H
@r203
CAGATCTCGATGATGGTTACGCCAGACTATCAAATATNCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGT
+
,,71(C@("<*$:.4:*>25)!(F(5H8?""GF,(7*E,:;+#0C99A;+E8.)7()<$2%;5@.;>2&().6F/!6H%A(<&G('0$GB.5+D":1=.@;+'$/#(B"@542H9"*BD3
@r204
CTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCGGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTG
+
<:!A.E@1(<9+D>44.%'#7.F(972925:%15CG.A37(2!:5??&$-E5B,H77'D501;&:,!D.7%E1#D6F*(#+56>5'B?;*8%B.,5C32E:-1=%?D,28F=DD1,2
@r205
GATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCG
+
.CE&@-.C<C/@@#<D@66@9=D6($5$=>;44H2E0>B%)D(/:#;"+>167A,*+/3
@r206
GATCTGGNGGAGNTTCCNCGGCAGNTAATCGAACAAGACCTGTTAGTANCTATCGACATCATTACGCATCGCNATTACGGGGTTGGAGGTCAATGGGTTCAGGANGCAGGTGAGTANGTGCATATNATGTCTGAAGCTGGCATTCGCATCAAAGGAGAGTGAGATCG
+
&&#**%$%()'(!'&%'+!&)+)&*#"$&&*+%)*"$&$#"(*&!&'+*)&#!(#)!$$%$%%)!"")&'#$%"*!*$!)!"(('"!*'!(+$)"*'%))("(%"+*"%++(*+%$+'&)+!""!+#'%$!""($)&$'+()!(!)%'(+%&*$"*+**$!"$#)*+
@r207
GATACCGANGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTTCAGGCGGATTACAACATGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGCCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGNGGANGCGGNGCAACGTC
+
E*2":G7/F2;2E.7#E/!&57/-+!4F93H!;$/)?)5,>B6-/G"F1828+%C>H1G:&#2C'+73F:$!24):3%FB!!GA#?/F%C&$3G6$/<,=H>5;*:D*51%H',EH>*)01(.%2?$*+*@,)0%C)5/+..*96A'?)';>3(F>=)%08674=30-39"G+G9'#$9@<+&1!=;?&=<9<-"&B&7%D%<G/G(9BD0>;$C?'*H0',.6($92AE8/<)65D'2D>A<EE*</20!H*062!/."&1;80<'3B(91=H/&H(&6:*1=!%D=D&6-0F),6*;.B>EG!E!(F.9(B4H87'*B0!0=C9+4G-4D#$B.E1F<-B!!D(&*7*719339/82+D2B;3F584H23:;)>$9C$0.C$%D$!$8)
@r208
AAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGC
+
65H7%AH-3#*=F2#;E8$*B5@G,>73%'>A$D@4@:D91%3=@<+2(%2*?%?<20!.)?3
@r209
TATTTATNGANAANGGACANTCAGTGNAGCCACAGTCACTCATTGTCCGGTACAGCCG
+
(('(%"#((%"$&$"%)+"##&&"*"($'(!*$)*("$""*!"!)"%#*%!+')#!"%
@r210
GCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGNGCGGAAGATGCAAAGGCGTCGGCTATTCNAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCA
+
.!&B1;'2!<'9!H0F)<&7>*-2E1.(2G9"H(:H<:#$.);/:'>H8CHA*;%,5#3D!D:#+6=-GB,F;5%(AD0(EH3(:1B+:;=7'7D,/5BH1)BE3DFE1!2&8-6"&$A)9D<G!C0<3H!>=6.6<7;46E?'H%+#<!F%G$!
@r211
ACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCC
+
4&51>:/C7!G?><*,1<@4$/&C4!0,4>=3>,$5>"CBH)0EA0CA9*G=D<*FC;E:F:;853E'D7/6:
@r212
GCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATA
+
(>.(26;+,@E(E/13<=$;B<7@-">HG<G;5F<!"0A:-A;C$>B8-032?7$53$9.&6->-4;%G#"'60)2EAH>HB2A,GB&)0<&G%#;6%$04%@@BE@).@A"E$B'/2,G1<6<<*
@r213
TATGGCTGAACCGGTAGGTGATCTGGTCGTTGATTTGAGTCTGGATGCNGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGT
+
F%>66583:$G-$"#"$%06B)B/.>@>$/<.E:$F<)'4>63*C@"*E%5'=+C!H?-?-&E%-?AH?8&.((@-40+;H,B>5=4")'%79C@$*2"*;=5!/1B'@=*9*"$%(18)-G6+2.(*@C.=
@r214
ATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAG
+
#.H>!@%7H8=?<DGE@2*7F+;-G64C1;:'%>/!-*<D<9@#0GH
@r215
CGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAANCGCGCACTACTGGCTGGTTACCAACC
+
,,84#+5/-+&3#4.++A$@%4GD8D<1CC<4%F631C++*8C$3!"421'H(<9BG,55@52HA8$)F+H7;&0F8)0+(@A<>1
@r216
NCANNGCTGGNCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGG
+
$$&*"++##!)*'''%"(%!&+%"*(+%&$*&)&(+%(*$&%$!%!"%'*$)*&)"$#'%)*
@r217
GCNTTNGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGT
+
##"&&$"""+#'(+'((""#%*%((')**((%)#$'%)'(&(!")(''(((!#%')
@r218
CCACGCTCTGTACCGANTGCCTGTATANGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCA
+
>2?HC5:3>>-,++&4>??,>C.H8:2(7HG/;@0A<B1<285+-&%@E'<48$AC+H2/G:D;00913D,$.H*.'3-G5DG.#.)"0%<8)-20DB9<>;H6H-E9798=77=H7!#H$<4E'G!8#-E?*9=*6#D@C6*,?)-G-70%;?F)>)=.6-%=A@B)(B711;.1
@r219
GATGTATTGCTGNTTTCTTTCCCGTTCATCCAGCAGTTCCA
+
=F7.#541FC*,$0'D'8#A,673DD@#'14C,A*D!"<4;
@r220
GTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTNCGATGCTGATACCGCACT
+
-4-7A5$9(@8@<8+-2?8F8$?*&D0!?>574&1BB).%.(:GGE,(A9@D
@r221
AGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCCCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGAAATGNAACGCCNATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTGTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAGCTCCGGGACGCTCA
+
3A$$B7F/7@6"/0,FA:8:!&BA&5C)GHD:-37C=$@F-6)6&3;6/7(($<6;E<GF1&#!9(.6."!E-!?%)*HE>:*G@!-3G0"->46EA!G;'9)G:,5<%/18)>?.=#?/#1HAHG9$<")B=C06!*A<F9<&E,#:0E3>,<%?16B#H$"+<*B,@<72A(>:5!=#'E5<#";&!H:;#AED<2G@;H?-@@%55.=0*18%.8A-.*H/.3C"@.H%F2)6/:83<DE.@F8#17'D+*>G(,<9!-:E746A($3F>:"%!B!1!A2*/68@03-C<5.#@?.'71*+-'9'7+DC?7GE#)B+CD#9/3>F,9.!!GF=-93+?:'1$B&0-5$#3/"#HB<-);H196:#,91H%:$H:0=!.
@r222
TGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGA
+
A@'C$3;:/,%24B4G=?=>!35H$6E4$>/0?35;+G;9F.!0*;?C6C
@r223
ATTCAGGCCAGTTATGTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTANTGAACACTCGTCCGAGAATA
+
8$+*A-%>!CC1><5&?:0&?%7FH<#/2-/,B9GF"&)'?6$4F>HA?04E!6.(#(>B>+;,#32/(5(;3=<%,/75C>&;6GC4)E2-3G4C8EG-7&4H
@r224
GCTGGAAAGTGAAACCCGGNATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGAT
+
B)+789->:H#-!GC0G'45A@=G7?0#-8">":<4H?0#B68G8*G12149,88<8.93-+(<7:(9
@r225
TGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGNTCGGCGATGCGCTGTATGCCGGTATGGAACNGGCAGACGCTGACGTTCGTGCAGGACCGACCGTC
+
D@&<+A&./'D4'B%&"HB+B@:,+G9;3'H><E$C)8:5.HGC#1.%0/G),&2+?BE*)A'!HA.E0D+1'-?&'E6<6<0>5#9'2<3<4"+7%&=!(#>@7E/(:60'=2(..16F8@#7<30C(F$8;7<663<25'+6C8)
@r226
AACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCNGCAGGTG
+
@,)=-;-:-7D439$.)(+"%8151B&)*&=(;53@@$&F"F9.!"&B8A*D(@:F*48A2+=<A2#!+*=,1A1G.*A#B-2;'A4G*D"->HC3#;62%&9"-"&CB
@r227
GGATCGAACACGATGNTATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCT
+
B47>'@0?)'0B?:)="913(7$<00.D.@!3C/?&'HB$!#)'7#C%)'/F@G!3?4C*:=*-C.&7E?E/%4.H5?"<8:&>#<@'*&:B@EBAC;A;E3=1)H<:(F.$$*F)90?&/36!9,<?8.
@r228
CCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGATAACCAC
+
$G)$977>$8::;&"/0C6@/$H)1;%6>=3$!8%H;(B=?H;/3*17+&'26D+'0""$1%BEG*++%E<&31B:86@##"">;()C!G:-E708BA:)8/(6F)(4&5$F+>,1-:4+4?8@F@0*".26-9+6A'3<+.5A!8*#&&4;8=?G@3?C?H</F(47:!>!3>B!.1+#F4($("G$,F2<8&'*@+>9).EBA7*=#&0=?0!9E3D-"3!1.7,<(BA53=C%
@r229
GGCATTTNACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAA
+
+)>=!039<?1&"57'!(FG@'5>68A871$"<!863.A%G$H0F/
@r230
ATGAGAGAAACCAGGTATGACAACCNCGGNATGCATTTTTCTGGCAGCGGGCTTCATATTCTGAGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCANAAAAAGCCAGACAGCAGTTNGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTNATTTAAGCCTNGCAATCGGCATGTTAAACGGCGTCTTTAAGGAANGATGAACATGAAAA
+
72"8!$+)!'E!G$%,&C=F@,F6GA+BF0>6HFG!05*<$F3,FG:B87B/-5:#33$>>.%!6*39G@-.9<A+1%.:G)669FEA#%E@C7,CA28F#55A,3*"7&H#<:2A!?)BCA(1%!5A3$AE7?H'.B2?@731,4CA#'-G5G=./;36>A"F?#H17;!?0/7877<8!*%>3)79CB./%@F4%.&'G!AA7-8GCD3,%H'B5?)(.?=-D*78D"9A)./EHE8DH@9%4D&%='"*BD@"E-2D7,@<4;!+=)4'$/8C57$DG3=:+2%*.0B.**=71!,>@(E."&*CGGD">=)7>;FD
@r231
GCAGCATTGCCCGTCANGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAA
+
F#3&=A+*7''@A-08"7*;.<CC(%@4$-HE;/@7A1:".D?2,-40+E7+A#;/'9F/=5A
@r232
GNGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATAAGCCGCAGAAACGTTGTATGAAATAAC
+
!)F(@H!.=/?!!C25GE/-%+*B#7?'FH@/DE/H9&4C<:3!8/C;,:.;(+*>&#H&.)-
@r233
GANTAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCNAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTT
+
<C<F,A&//=*(,FC9@,+6'91&(E4&!H094?.7'C2#;0C5B/7&>:>":582%):8DB+<!&-3/(?C>C-0B*'B-%&H:*+2$+5>G#,;C1F&G2@3;2!?AH5/*%=4F=G</!33
@r234
CANTCNGNNNCNTCGGNNTGGTNTAGTNNGGCGATTNNGNNANGCNNATNNTNNGCTGGGNNNANNGNANTTNCNGC
+
"!"#!"""!!$##$#$#"#"##!$#!#!#!##$#"#!"!$#"#$!!$##"!###$"#$!"!"##!$#!$!$"""$!"
@r235
CGCGCCTTTGATTTCTTTCACGATCCCGTTTTGNGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTNCATCTGCTTAATGGGCAAG
+
8&FG#F#**6,>5@:0D3&7/:'0%@37C.!<<D166C4.,*'+?,6$&%7&$D<C8.$528-*D&&(6!,D&54C(?.@@3C9A-+-=$60?!B%1.H2C$$;#?2)B'&-(540A#96-60#9#1:#"1GB6$/D)44D.:>:B:GA5%1C*3<!5$7027<F"3B=(6@=4?8%@!6C+#@20E?:3B#),!
@r236
NTGGTTTCNAGGCGACATTGTCATCATANGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGA
+
%)'$&!("$!(+(*&+$*%*"!$'(&'*((""$!$"&(!"*"%')&'")&"*+!+)+'#))*)#)*&"""'(%%*&"**+#""('((+*&$#'%*")%(%*!*$+$+"!"'#(*&
@r237
NNNNTACTTGTTNTNNGTCATGCGAAATATTTGGAGGGCAGCTTGAT
+
#&"%$#%'')$("(!")'("&)(++$")!'&%)%(*'''%*"!++("
@r238
ACACACCAAGCTCAATCAACTCACTAATGNATGGGAATTGTTTTGATATAACCACATACTTCCTGCCTTCATTAA
+
-517+#5/HB4(=2+!G;")/;)#AD/#A,2<F+,?5>,9$>7!$=,#/.3EB,-B<(:",>52(/"$B<BF-G"
@r239
GTTAAATGAGTCGGTGTGAATCCCNTCAGCGTTACCGTTTCGCGGTGCTTCT
+
(+++$)*+"#(%%&)$%#"$**"!$!"!%)!$(+%'+%'#'(%$#"&""'%!
@r240
CATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTG
+
,E07+/;=%=3!41F>%B"!FC.>=4<=&8#FC")4>'12$>&EC'#1B%=."5A(C"-4H129:/@&E!F.C)E/=,)H$78+9-)7F!-=1+)?67%/,<GF>@F4G!>F;4=+*//AE!A-*@>>'>$7D00$"<CA*48<$7>))-4#+CE#.(A#@DB78:89>&F6="1F/E-A*H36E&&?<"G022;C.
@r241
AAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTNCCTGNGGTTCGCCGNGNCGAAAANGAGCAGCACAGGGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGC
+
:;/;A8!G0>@4:?-3@272,*B6+$892!5*EG(EF;-C$>88B.82E90%($!68B13'.G/E-<<./8(:C8*?=4*60;=2&#>,)#G+1BC03)E)H-82-'%F)67%5=5GAF5$<!7-(5?9'#7:FD4*9A(939F*-;F3/(6.2E0):4G)A%*#F.H>9@#"</-8A*
@r242
CTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAANCGGATGCTGCAATTCAGAGCGNCAG
+
2,26+390>&9D"84;&D?+)95(/91(,;<&%;(;5=3%5&5,"0E.G%C+A');!**>6C%/&&H6+CGB*%/4
@r243
NTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTNTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGC
+
#F%<-@H7$+(C(%1H/*6F$A>$6;A)<3'A@:'?/A*4;)C<">E9F/7H%8:HH-,9!'/%B2?<:,@,/)&)*E36;"<+<:#?4!=>@('9".#+#F
@r244
AATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCA
+
'B,C7,./3#8:H>05)F@71G/<"C)$F=H7%'"8.1@/;0:*A99HHH'++:9C3HCDA=>1E"2!@!>B,
@r245
NCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTNTCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTT
+
)-+=#70:"9A+/#B@D==<,*56GE90',";-H;H;AG))!*EA1?C@+>0-200%3;9;-:10:F=<6:-08;(/@%%H%9%=)=8G2),D9=?6+<EH<3'(-@84+?"HH(.*%3:DG'517D5&81+-GA;)7AA2>+?C4,)9>A%,$'0=E>G&(((?
@r246
CCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACT
+
85%-#H=>=;A"61&H-.(?>,/C9"B0B#/'153C0*<(-B*
@r247
TAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAA
+
.@G*5D"GC/@:&=C@#F":)=B2H:1168@.G.HF44)-3&=#
@r248
GTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGNCTGTTTTCTGCTGCAACCG
+
3+C:F'+@(DD1$+5FHGF('0&4+(A"">3=":2$00-?CG3F(:,2*@2F7@'7#CE>#!)BBH"8A?%C,+!H@E;(9?)%/&+@@!7&:4G,*+%&*16!69=G&08:30:1+&.<49(6;)*E'(0"432*57@F!
@r249
GTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCC
+
:$)B:%@:?F32@G!>4?#3.B)$$F3B$F#$()@A"=0$'DA.<6<$
@r250
CCCNNCNNTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGNTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGAATCAGCGAA
+
%)'#%!#('+%"$$(!!#%"('!()%'+#'!+(*)(%%%#$#$$$!*%!*!##+*&%(#*!$*)*&'!#$)$)#++#((#(#$$%%"&"($!"$*$#&"'*$++"*(+!+&+$$'#($()
@r251
TCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGAT
+
/G4C7/&$.F>H*+/''1*;9<#":<"HG"A'=E00@'&=0A$4=A4-"(;7>;2+E,>,E@9
@r252
ACGAGTGCGGTAGCGGTCCGGCTGTCGCGCATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCNCAGTAAATCCCATGACACAGANAGAATCAGCGATTCTGGGGCACGCCCGGCGATGTGCGNCAGCGGAGTCGTGCGGCTTCGTGGTAAGCNCGCCGGAGGGGGAAAGATATTTCCCCTGCGTGA
+
@+F5-7!97C=?&+C<5<E#B>2#5">E8)"F*/*$9C67G7=)1?;@"F0H*D>>1C&G*7?>;A51F-9690$A@<?*6"E?;0!G";,GF?A)AAH+@,(.<>?H&&A6>B0"D!:7>#,:94)@'B*742;/89+$#;2;<@>GG<FB==(5)(H7)EA2'AD7?@3%>,*$!6.6#4+49+&?.15"!&E-C)7A'&'>%?H<H*H-%$"(>C";,,2,?)A!?0*.5>$0'"&</E#/4+;9>'/,9?#G.92$35DH$B41<;-9%D>
@r253
GGAGACAGGGCTGCATGATAAATGTCTTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGNTATACCGCT
+
%CH4F/::%+%1H$"=8"-,F)+G86==41$>3$F3%72!&'E%F<,834!,51148*%?3)4B!'&<F"82B?F7'G,@790?1(6:64G*75@1<0"<;EHG%7##1DG!42GG?A(BC$GE2F-67#B0>(,=)</?$552//$%/$=C9E%+D<=H6663D(6F$.G)9D6)H/2EA://DB%)7
@r254
NGTNCAGACGANACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATT
+
#!*!+#%(#'!#%+!&!+!&")+$&&*!#$($#(+$&+#&'#!'*+#"("&)"*$$!$%+%&'#%!()")!'%$&()%*(+!&#%#'$!(*#!(%&##'&'#)(!$)(*
@r255
CGNNNAGTGTNACAGAGGTTCGTCCGGGAACGGGCGTTTTATTTTAGAA
+
(#$!##'*'&*'+'$%$(#(*)***!$)&)%%)$(&'%+'#%*&)'+(!
@r256
CACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATT
+
+A@$'C0-7FG@"'&@;*6;&H9,2:/..-DG;(=.26"98*-;4
@r257
AGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTG
+
-=A5&6)HCH%.C0)@.@,;H'"1A,/?EC?:"3<"'2#+!B;5
@r258
AACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATTCGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCA
+
H"?;(H(B%9%;,*7EH3'<9652"'H?,757,;C$E+=@8)/@,(G/'&"$1$&E>053%1+3)F?AH')<4!+GA(E>&FD=68H>;:GB+CG.:FE
@r259
GACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATGTTTTGACCCTGAATTATTTCGCTTGAATT
+
C42G1";H(G&E41/F9*7%B.D),,A?F4$0*+=)"-G>>5-60D656"C$'F6+9/<12974D6?:G(>#F<?
@r260
GATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGNGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTA
+
F/,F5*>C$0:HF/);,4<)*87FBE#HG545GF=F+$(<B'31GBD,=8<)(9!3H"8F@7?G)5@,$?8<!'97A.A&;:F?.:$(E6D0+-*20H6HHA#2C/?8%-7<C;(D&3$A!0)""$#41G/67FHH@2#+.A/#G,?$?GEC1+6!7@:-#,=>*%>C33#C(-7/0H!.?@8+?G/CA=?.,7=.</>E;G??:D<E$<(
@r261
ACCGGCCCCANGGTATACAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGT
+
D(+-!><BH1>)#%2)F-?*<).*C?=HFE9$%#A?=G*,/BH52C?H:)<,1*-,("BCD0F?2@/-5!(0F')-A8:/D7F.(@C.=D/"0%:21*=0@B1#1D2&@A*"%?72":,AH(3$;'>98&D16AH"?$$@E?#',E>$*8//A!=.
@r262
GTGGTGCNATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCNGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGG
+
6##E/9-3*-5E31):=8=80)>C+0B;:?-H>E)9!G$EAF:E7&6,?H43#E8F.!@:;==!?C3;CH2#D$2D6A$2&44%>8597%)EEB3=#%94>5;H3C9/#58)%">2G2E8,#5)='1G15)<6))%B;4=A-*>?<+02<+'2F7B0;;4+03G0G;2F0;6)#8@&CE8E/>,*D9F:/)++8.<F,*A.#?6)D1$1/998@"CG*3C!(A%G4DE1B!*G
@r263
TATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAANTT
+
EC9>,#1<'<4'1;0D*.85@.5*&<6,-<;<!F%51C)/)@3DG7"2*?#'7#&.96B>=6)+(F/E>)?8/1!A4&G6&/-=6"%5+)&%HCB6"-2A1:<2'425>%&6#@>#CHE98&(('(36=/D4876,
@r264
CAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAAACATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGANCTGAAA
+
C/*H-;,(9F+5DF,0(4B+)6>(A:94:CF#:-,:8$#<B%)-$GF=*A>-9G5-G&;AB'E>H;B3.#:D)A@-,4=@3<4E5"E'&8@'B7@F-?1)30/4&EF!;;%AE1B/,;)G4%=(A0&.$+,)9>B<0.;D;:'8:F*&(<3*4;6-(0G8BG=(*5@2;$8*8./0)$7.&*,#&0!@"1&G6:8'6#8F#2D4?!B(4'%*>$1A/8G&<F8+902"-&4>$<5%$F;>4&-!'*+D"2A;9!<"*C2/39(&(EG>F?.D>":7'%&B!%+6,#,,-$!9)6',!7,'6G:@9)44(,31F=,;5*%)C#1;624+/G<6CG5,%>&)4B8&H5C06585@%AFDH.&0/)/>6*0=18#(!@>/$1AA.,D1G18!@G#F,+;;@B=;*8E=@<"BC@H2"7B)0'.7:.$H/!C<(9#*37+B4EAG.FC(BEE&B.20!)%%';*&2
@r265
AATGTNGGGCGCGNGNNNNCNGGTANNGNCTNTNNNANNNNNNTNGNAAANN
+
#$!"!""""##"$#!!#$!!""!$!!"#!#"!$$""$!####!$#$!#"!!!
@r266
TTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATAC
+
4'0@-<@*$,=$4#'H3$-?1!@H/)"9=.63@6@;GF;%)3;B>
@r267
TTAGCAGGCCNTTTTAGGGAGAGGGAAGTCATGAAAAAANTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGNACAGCAAATCCTTCCA
+
!;A&<@<82A+7#E8#3D<>C<($AF#@2&>H,+#5#<"))B2@5=>)E%C?&!FF)F5.7GH01#2&#")1888==08H+%#$D89+CE/8<(78"(%F#EA(">3'
@r268
TCACGCTGGCGCGAAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTNCCGTTTATCGTACAGTTTTNAGCTATCGTCA
+
,&HC1#)5)A$2"$;H@-=A/.0!8G;!"(F,FD*#;.7@H$1$9/7-'>(!FA=9,B!**?#E"*>,=$*D9BBABD@+.9>?+,A3:/9E("9863B:)*G
@r269
AGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTAGTGCTTATT
+
C64=E(G('@1H9<8(%F+2)$)H;#DE(F*7E5B#!F<09'D-36
@r270
CCTTNTNTTTACAGGCACTGGTGNAAACCACCTCAAAGGGTGACAGGAAACG
+
'&("(&$)+))))&$%")$#$!$!*+*+)!+'+'$$%($)*)'("'((&$"!
@r271
CCAGNGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTA
+
&+#"$#)"*&&)($)%+%%##%+!!'**'!+!%%)(($!(&"(%(&"")!!%)+()&#+*$"!(*"!'&&($&#(!*&'!"())&$%)+&(%*)$#$$&))(!"%(#!$!(*(&!$+$%#"&&&'$%")%
@r272
TCCATACCGGCATACAACGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGNCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGC
+
*&(+##%*&+$*""''"**+!"##)"#'$&')++#$&%")!$$#!!*&#$'+$*#&(%''%)!)!&%!$#(*&%&)#"$#*&%+!"%+!)"%%#))+)))((""'(()
@r273
TNATAAGNCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCGAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGTGATTTTCACNAATAAAAAACGCCCGG
+
(#5<>)!2=(>&%!"=?$7C+:#.;>'C(/D'G,<1*885B@::=671*7@%"@B($/'905:7/+B(<BE,;CH56:%>>03%3!H%:',C.H5$$G?EC6.E8#495.2:*'2$!&@+26*/H09??<'87''!&#>)2G#),3%EG
@r274
GTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCANCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCACACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACC
+
A2(?0$(0D<'@*22#2,.F(?8G"=ECC+#C%+%@4>F$5?("'1;+!,;D'8E/".85C*G4)0.FH1#+84=AB*"F;/,9A64*-H2*C#9(,>CG@E,B)A;$4*-@',=?,AA(?=.&7"91#G"A'3$E==*)$D9C.A">D2'A-+H7@/1''+$4677>F;6$$8%H<,94G8E-F";FC;8H(:")C.$<H;:.A
@r275
TGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAA
+
.6;GD7?A(7!/GFF4,E=/H,E04E+%1F*+6B>=&):,#A!*?3-04#G4#15A@8/+EH:
@r276
GGCGTGTTTGTGCATCCATCTGNATTCTCCNGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGC
+
51'FA+>),9.B@G?F"12%)$"<"7/3$/;-&E$D3C8F*=")!H;8?GE(E3'05&$G'97)!*=05=@>;E(,/5E?'$0$.#&%7#8=5?*DE*#?:F84C;5%'?:=8@5?/GGA$B<BF+C
@r277
AAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCAT
+
@$)<H)>EC&09+..-?$29*>%/B9EE;>$;C5402$);H$)/:B<
@r278
ATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTC
+
.CG$(1=@.<("(FB"&97/=GH?+*4638G:G:4.%(G-7'/%9?F-E05:90%82'E=)@&E-2;!C2=6:.?C9CE5*$45+&547)&,&=@B%'GB&G/7@151A*"B@-C6F,2#",+0++*G*C+G:-#8>9%<5:DB$;1@$=%1&*1-F)6,G"/4?CDG2-%&DD!*<5"3,-7>/<G#3@$6%<
@r279
ACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTNAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAANTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTNACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTC
+
7/$G!>.C06./:;EA9?;0#?F@$3@,4:!/H#5./?-(?E":0>E8&1(@(1%+'FB27&71H%=4%3<+*'<;=GG59!%5C2(F**%(87":./8?>'.?>+DA,8A$>+(:8*)<)=+(8A$!-H$F=9DF!D/3B-3=$F3-58%--8&8(#+53&B4?$B,F?#D%-,&8+/!.$1?4<4>@/D?@E%265$=$(//.;HG/*:)?DH"51&#2"(+=447)8HA80,37:E$HHG%)83.,>*6E%&205@('H$>E;#0>>2&"$'F!:4+B4%.=>,'A?8;G;(((-277#:<AF-'EA:)220)"(4/)$'F3"*A0<2)G?C?8!4.!*,94D2?C,3H,.!*@5/GGCH.9F?GH),DH1'3:H$=F/0BCH:<?>A?3);4@(+<C%G0DE?D35FG?,2$%4HC*&'14G;&0"E3++0$HG-<13=9>4E50-,;A3,$
@r280
GNGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTT
+
'"321EDE%EAC2-(:B=HH7'=10.C">A$HC0,8H?E9G@*2(2)?@B,(&;).@9.5#(%G+19.8$5'<84?E51F$8#@%==,4+H6!H,?A4EE87AC>57&&&3!$/D%++E;9$06%)E
@r281
AGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTG
+
.::&3@C79:'C21=G17??=.&4H1?9H3?8!39&>6E)A@3D
@r282
TTGATGATGCGTTCGTTTNTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGT
+
H%H6&0A7@%814.=FHD14G<'-3+C?:7:7:$&.<20@#,BD,F91"G'%4%1=$:"
@r283
AGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGNCNTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGNAAGCATCAATAGAAATTGAAATCGACCATGACGTAATG
+
#B6H(:'C&>652/$C3G<*$:3E2H;+5EC.?D>1F@+@3'AAE/+*B/4E9=73#6,1>A4=,9E&AC:(?5%/+/8:G977HG9;1EA>"3D91A?(/7>1("0-&83&<C1?"38?E3&*D1!32=G!&0"19+=E67.:8A""<6'F5@6>F3'8>
@r284
ACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGT
+
65G!!?+F#$2@3>&#C,4:%<?!;24-?27CC!0&F8%@B-=H$073*4$/C9$:,1$+3D#663B@)/=927!+C<>-H)
@r285
GATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCNTTCACCAAATANTGTGATGACCATTT
+
<$&,>,55D0?.B9-47'B5'5E.6D;'D"BE2"B!9G*A8H!*0?B!*56/,G-E1C+4?"8.H(F#.;/(-&:."5'FH*=2?,H)4G&;(E75,H+&(>0.:;8@=!B!/<+#98,*3>F(F;B#@3=5(86:;
@r286
ANTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGNGTCTCTGGCA
+
&'++#'#+&(*##!*!$!)$%$&+!$!'*&+*!)&+#+!+($*#)''"'+*"$+'!"&**"()("))"$&+#
@r287
CTTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTC
+
(#H-,>:94'0?8$;2/A5:-A66(8'(#4%0-?A!A#;G:F,&($9+1F8!*G:)<917$&4&=-,?0+4A&!?.FA
@r288
TTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCT
+
E"FC@5>)7=E';<)90#ED@89#1,C?CBB224=*A*E9('-DBC-#8=%H:,.;2:C488/F=42#/0.E>//H(-9
@r289
GTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTNCGGGAAAACGAGATCACCNTGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCA
+
','1A+-,78#8==)D0$!;B$B@13<&0:BB$<4H1/*&6B6>!+./'*87>"3..-).?<@.4=C%3+B(57;%G=E#A2%HH?/G1$4.3;=$<@87!;.(#/G0
@r290
CCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCNACGCGCACGCCCTGTCCGGCATCGCTGATATTTTCAGGGTCAT
+
;9B-$)/*6##11G(=1E%"69$!977=FBF98?6@)/687BE!G&46F46B7D81!!C.9+";2?=->?)?,&/,&/H@/5EB/7A,?3(;@6?@!#*.">5;F.!84<=:-/2>=834@AA384
@r291
CGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGTTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCA
+
3A7FAACACA:F'A;(<97EA29@5G,?@FF9..5A81A27'$-E;(5D)2%:+"'76=!$D8$>4%6.9D0,4H1EF4;BC0H@2<%4H;12)E=C#.1H$/&D)(0C&4!'GC7)2C/;(5F28&G4?70HEG
@r292
TATGTTNTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGTGG
+
H$D<).HC.0!1F")"/(5@2)*1/H+9&<%D5/)?-%,&)F*?9B6/=@"D8(77"+@@/"1;.;&/&C3&?*G@4!8E>*1=)&F=H)#E3,%4
@r293
TTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACAC
+
&.+2.*8@82!6HFG(52$<G>8)3/$#7-4"*7,#@=)%>6$3)"+HA-@1>G&
@r294
TCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGNTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTG
+
C5&)-D)@*,,5&'=&G40??66:-;3E(D2:.<*;+>B.#.F=*322G(+.&'98<+0*E'.6<8'F=9:275:1D+//7?74@2H3G;:(A,?.F;22$&C7<,>49:=A3*"&%GD65F,.&5E8"5@A>G5,(D'GA-11?B/4$B5,)&6D''+*FDA22:-2#"GH@3?D,3;;E'A8'8=*9"?&11)"*277G1AF02#'+7=(6
@r295
CACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCC
+
)>F4@-//-!&E>-4"FH5;$E&9F8C='!;!BBA-/&(3(::/:7)E?4*9E-2;.
@r296
CTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCAGAGCCGGGNGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCAC
+
F=$/0@))B@6##!%+##AFH4F3A.%6F)C7$<219<A&6(-$H3#52,&>E10:2A4'(-!B!!>=46?7(@H1)D211F)BD-27<.53>7!C)7",>);2-3,=)?9=-?8:!/="G"&A:+<F?),D#/C!.$)%=D,F0)"0:$-0)F09.-#-E&3"<D+39+H$-<E<220F&*E=0#6*
@r297
AAAAGGCCGCAGCGTNACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCTGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAA
+
++++2A-)B=+7-62H&H@'=0G.>/1+E9E.)<-+$97D%4E?G9>.0&@03>$6)/><#30-;8@35;D"8/#D:A7!!/C/=/(76,G79&F!7#8&5.#!+@/71@*A@9%A9#@44(5FBF(C92@"B'B"!=>*>;@""H$7
@r298
CGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCNGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTT
+
;::0-2)H:59?-D!(.";%/61<:*$;1B--@#.=98(1:H1B*<H$9&%F*HED"@C$B"D0#6$C&(*-/#3!4:"'D2+7#-&4-7:0#2!E"+&#/)@&F#+=C@,!=1AF9:70#><D+G790&&AG??/@#
@r299
TCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAAC
+
4C41=8<A$<9C2H2??E/):A;5129"ED@%<G,F!0=D,"$%"1/?6"
@r300
TGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTNAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATANGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCA
+
12!H3AE//0,7<=?3$$<&9<1-/<)30G+DA.*FC".7C0,4?@5."8623-@#(G*&"29'H)?B3H.=6)4*4B23B:6>A.:/A.@+CAB)E,4*GC2*@"!$.BG!>2#A*6?+-#?;05'0/79-(C!<)'EC;G$CD+
@r301
TGGCGCGTGAGATGGGGCGGCCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATNCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATTTGCACTTTTCCGGGCTGACGTA
+
5#3'>$B5("8#<:A!F7HF6E,+!%6>:0@662H1H3-0=:0.H4+&#.)%!':+=#2.;?)H>G#@8.&0"&1E'&?;FF'AC&>=)6.$B'"%+",%.&=02@5D)B/@GE5-%7A!<B6)F00'H%?G;&#GH5<#D<
@r302
CNNCNCGTNACNCGNANAACACNTTCANAAACATTGNATTTAACT
+
%%%'"&#'#&#"")%*)**)*#)!(#)$&+&!!("!#%(%+*#'!
@r303
GAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTATCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGAC
+
2#4F@C69E=066'*?7G!/@<3BE5<=;+5F:198=&,)2>9A"B='/<3G"6;61!@*;4(<C??('9+33,,3:039-/;
@r304
TACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTACCCGACGATTTTTTCCGCCC
+
=2?68;C.;@G'9)<14>/G(2@2H47+:D'B:8:@6A56<+'4?1/G+(*@1$('562B)-*;/"#0->7$69=!0.7:5@.05(8@.3&0).C@G16H'?1A=#.(1"A>C'1$)276AF*"%!=5=E%#>HD#?)=.?H"@9:<:>6"/F5.B,F>E.*A2'2/!
@r305
CNNCGCGGCATCCAGCCNGGATACCCGTCCNCGCTGACGTAATATCCCAGCGCCGCACCGCNGTCATTAATCTGCACACCGGC
+
%$'%++'(!$'!!")""+!)'#!+#%(&"$*!"*)##(#($)+%!'#*!&($""%%&'$"$($*%+**#)+$!$**)$+!*&*
@r306
ACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTTGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGCAC
+
146*H8F8FA,5G84'%++==>+29F0=D=C7>/-%);97)BB+35C294'"392<@!)E=7<,F>!D<;2DA..C1=(!EH4:$/:++D*60&5:&D,3%'-#HG55$;HE0F>+9*/:6*H$3.)*=$F1?$7G9BH6+=%/,!(%911,H*10"8*4$#51*?!B.'#A28.';39EH*#4,6*'E.1;D#<-
@r307
AGCCCGCGNANTCCNGTCNNNCNAGGTCTCCAGCGTGCCCATGTTCTTTTTCNGGCGNCGGGTCTGGTCATCAAACCCTTTCGTTGC
+
!**%%("*!("$'&!*%*#!$%"+"&)!!&%#*'$%&!!&(+"&!"%&&!)"('#")*('"%"'$!)$%+!&*($**"'(*(("+')
@r308
TCGCGTATCCATCGGGTGTGCTTCCTGATNTGCGAGGCTGGACAATCAAGGNGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTA
+
-/ED9E/?H"&$AED)74--&7:6/FA7<2B-D/;4/1F7'6$9(>0./1!0&(2B==6-8@22:<C9H*2/G+46<('*&0,F2GA,C.9=7C>E,)C5'=
@r309
GATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAAGAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCNATCNACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCA
+
H*/%C?6!7*>5E6G6*H:EFD1=;C%+93(?5<".,-C#,=6@<"9%.G=#.>E"(6:&C29@:-;1$!)/5@BB*8*;5:(+111C>%=8@=D+<,.?;)4@$.EG/:AB8D:.0-+.%.0:"E@D<'-A8F7/%:#%?A4<%0=E@-?0@(H(&F*.5B@!)@1%$.<4)78@'F?&176<)$,E;56).61<0C=#/"79'E.>;>9(HG<#52!G1"9EC'>!#=<00D@F$)<#
@r310
GCCATAATGCCGTTGAGGTGAACNGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCNGTTACGGTCGTAATGATACGAAGATGGATGCCTTTGGCTGTTCCCGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCNGAAGGGCTTCGCCATGTAGCGGG
+
+*%('#"&&%+'!'%&'('+$%#$$("&"&+")+&!)!+*""#!+#+%("$"#)%+#!!+&)&%$*&*$+%"&''%*))(+&+%""**$"(*($'%(+'**$()!'!&+)#!$%""'"!#+(&++)+%*!&$(!##)!$$*"&'%#!(*+$!#!(")$&"#'*+!$$$#!*$&(+&)&$$($"*)*'*!!$&")&"&"*$&)"+'#"++#&%&+)(!)+"(!'#+"+'&&(")*"$
@r311
GTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACAT
+
.B5CGG@-#@4=>G'%7#?=@.$>$0)9C-)!F7DG6C7><+@.3DE/!+BF%7GD!1BG=8-4.BG/:0-3+!2#$4&?5#(+)7B/6),)(B),,##5DD@4&?/*&:F'/((-0$97!5>,0?&9'!8+C@?G<FG
@r312
TNTGGTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCT
+
"%"""&++")))*#&++*'*$%+(($+&**$%!("!+#$"$($$*"!+'&(#)+(%&**#'"#+"&&**"++)
@r313
ACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGAT
+
>"E>C0F@@6G"3BH7'D4==4@+'97&H3>1!<<%=:1(?.:B#*&@6,>AC4/'"703C120?HAA0=674<&-EFA'#?
@r314
TTCTNCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGANCTGACTCGCCGCCTTC
+
>:B0$81A#@,*;;/,4=0:C/"#2B9GE$/7'#*G3G2(>G'>.<9D;@+8(582.>!-54/!696@&
@r315
GACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTANGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGT
+
$9@F,'8/06)">+&-+5+!</66#CD'A"!F55":,1/.:)H6:8(D9FB#B50,B01$036'(G+:E,2BB53;&+'!"ED/62"#"@C4D;4!G>F5<-D16-'-B4C1/C8B-F:C->$!65'?;:=?-$FF-??3%71:%)8B>55)/943*
@r316
ATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCC
+
,3DC26%1(/H5B;!E:@@)!+>22B$06#)AG:>H2>+6@5%B2=#;*02@
@r317
TAAGGCGAGTTTTCGTATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTAT
+
(G150+2!@2HA:!"@'DE?/#E(:(!D<)D*3,?-!9A((F(,+=.4G0)")67=$5=-&?8D593F;C'9#'9H7+'&&+*&G,*,DB35#2;6D:CG=F3"*?H7!2"@79&+#
@r318
TGCNAACTCCGNNACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATATACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTATCCGCG
+
'*&!'#$$*$'$#+""$+!+*'"+($"!)'+)*("!(#+#%!()&+'$!*$!)%!$*+"*'%'$(&#(&&*%"#)&&!+')"#'(#)#""%'%'(($(+)''"*$")$'**(!)&#+"'(
@r319
CCCCGTGAGGAGGCCACGGTACTGGAGTCGTTCCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGA
+
;C7@%?A@*G2.?D9!.+),&1/G7?F*GF=?5#4:C1-($1:%>'>0A6?A*<H/*'=1>@H&#45B69/1?,A8H=:,-EE$C/EF--$3*A
@r320
GTCTNGTGTGCGACANGTTNGATGACAAAAAATTAGCGCAAGAAGA
+
!'%&'')#+$!(#&%$$)!!$'+"(""##"%$(#&*"&!%+&#"*+
@r321
ATCAGACAGAAGTAGCACGCAGANTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGG
+
/5(@)"8F;3*H#>+'E/4"94,1F<&6+"*C4;)#6+(DF49D&1C'%G8::A0.F&>3(FD.G<9<.=%G3
@r322
CANTAAGGGCAAAACCACCTCGCAGTATCTGGNCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGC
+
'*":ED+%E*D&/89;8.;5D%D4,#H-;"#8E$7!7/>2:#@9="5@+#0@($3%?'41(*357&68>4571%0"%-3AA-@E+
@r323
TTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGT
+
-87BF5"274BG,=8(-'>1.)2,"39>:!FC#<".?";.+*H7B+$>2@DG.>#C5(2/&4:31A3?*($G?>7
@r324
ATAACTGAAACNNCTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCT
+
"(&$&'*&*)%!""*+$#(%&(&'$)')%#'''$""($#*#+'"$+!'"%&"#'%+!"*"+*&)"%+))'+
@r325
GTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTAT
+
/,$FC+'?6D'/()01&%8*1+'#-875#57G3H;/?785BC**5C809F4:<
@r326
AGGACTCCTGAAATCNTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTC
+
:D@=1-7@EE8"BHG?(B;GD-D:/7"/>*!=0+!9<G%=B=1%&E'?E56F6,;
@r327
AAATTTAGCTACGCTTTCGAGTCTNATGCGCCTTCTCCCTGTACCTGAATCAATTTTAGTTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGNTGAACGTGTCCGCNCCTT
+
%%58!9A&?F@%CC7*:!4)792:&"8BE?8CD.%<4837*#3/GC:'"&D)G;#+68(;*D-1&2/81/D5485>C=!6=0<D-D"4G$?4)"FBC'>7'>:A8&'FB9;2')G/!0B:2)G!AH'32?%1&"(*#3G/<DA5F0:,B=H@EH$9;41E
@r328
TGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCNTGAAGATAATAATCGCCAAATAAACCAA
+
413+5,708E(%=%C<8B;?5C(H3+/*:*F9C545%6E*(B-"89:$-A0C8B0!>E(5$,"."H;)@=$<:.#,0D'+%@;
@r329
AAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAA
+
G#?7.=2?(@:*+8*@)'9?H";%;.49?7@.F1)1"#%8@403(50D:16/429
@r330
TGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATAACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATG
+
#7&4$$0$#%%C9)7."*BHEA!>C:$8;'1,.EH(72*DF"/"@(FGE"6$4H"+,1>D30"!55(!B+;002C00D#<)=,AC"%*2D?&$!<0F238A#83H#2H:.15:-71A'H&GB2C9&4>H7*6!6:C%1:(%2G,&"6G$G
@r331
TTNATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGANTTCTAACTTGG
+
4C')/?)A9"8+"/"+=";;'EEB4"9G@+9AFH3C-8?9*:%5;94H?A;6':$FH&H*$?<1;
@r332
CCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATANGCCTCAAGCAG
+
"+!%$+)!!*($'%+)(%!"!%%"+!+""*$!%%%&(*##"$!*!(($$!%+#&"')!"#*##$%(#%('*%*)&$!'"%**&!++&$("*&*%$)*+*(&+#%&&%%"!$(&)+#('&%"$'$+$*("&*%))
@r333
GTCTGAAACGGTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGGTGAAACGAACAGAAAAG
+
:58A,H4F:9<7HB*<$H.9%52"5F!9G1<4;6@>5)1E@A;HB485)B&1F+&D%83,</B9,
@r334
CCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAA
+
)62C"/,;<6,87)C./8%!1:=!DA>*;H@HB*;(?59==:-354)H
@r335
TTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTT
+
)5(-EE:/AF6.$>/4)7-G?7:@0-(3@=18<;0,#.=B?/B6;/EH*D
@r336
ATCNTCANNAAAACACAAGGAGGTCAGACCAGATGGAAACGATAAAAACGANAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGACNCAGGTTGCCATTTTTAAAGAAATATTCGATCAANTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAA
+
')*&*%&*)++&%!+#&&&'*$"#%*&!'"!!')%)*')+!##'%%("'&)'!)#+("*#*&%((#+("&+"$"+&%+!(!"%#$((')!)'%!()'&)'%&(!&*"(+#&)$!%!'""'(**#!&(+#%&*+!+*!*%+!+!!#!%(**'("("'!)'")%#(%(+#*''+'(+#+#
@r337
AACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTANCTGATACCAGC
+
FG"H#<'>$>D:/;E='4@*3&,A"+B"&9>+?8.=+C:.F""?"(*:G
@r338
ATAAGCGTCGTAATTTTCTATNTTTCATCATATTCTAGATC
+
AE4+3#);7>E#H'/=8H3$0"F'FFE?='%*%%&)BF%D<
@r339
NTNCNNNNCNNNNNNNGANTTNNTNTATAAAAANAACGGAGCCNNCNGTCNCNNCG
+
#"!$#$!#"$!!##!$#"!$"!#"$$$$####$##!$#!!$"""!!$!#$#$$"$!
@r340
CGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGNCCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGANTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATT
+
2<,91G9++29*0$>0.EF4!6@E2G*?!04'@'30&C0"E,!/D$/0H=%+&C27-:+%E>,"3&%D$G/"+0.,:%</H:--DBB(4F62B+*FG-$HDC2#F03>!96(0",6A0;0/,A';&8$(G!DA0@58H&"+=@78;17?GAB.-7C@97=$(HC6>-@H-&9.+HC<=9/2+&71629B-BG::H1'A)0!39$><%#)*;F-/=G=+H?&4HAB!G#A38(,/D"<66H7AB-D-&7,H,D),@@$D=0?-%;=<3'+B#15<5B$!2?A0D+*!6A;)2A*#<."H=*B)1C7E81H5E&:6@8#6+922$4/;,HB#2:4<3D4)"
@r341
CCGGTATCGAAATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCTGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTANGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGAT
+
",)/92F5C<=#7?>$'B/+-;G172%@=$=6,3;G(:0D8#<"CH;1=CE/+175A&6%&=,3'=+/*3@!!&/7A3'75';=HEF*4(%0DG>;>&;B22C3=."/E0#::$6/@$E<199$5A2<A$$78!D"4<D6EG9->&!)%/--#GCE$567!=C$C@E#&9-&=@@579.06C<!:2F<"&A-3.EF0;G>.#F$(.!27"!:$7.9(6,.82)?DB%<46(960$30E?>A,59;<481C0?3@;B+E8E2E!H.9?'DC0=03G'#?C$3/7#)('(E*A9E&,.8,(>'0E>6*'7&F&)<=';B2)))8@7B/-ECF#@4.#@9&:;,#"7F&B4C/B6;H#-E1EH
@r342
ACCCGCGCATAGGCGGGTTCAACAATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTNGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGG
+
6(*/A8**&:=)*H$-!.<-,;$!FB*!%0H+;(A;GF$>?$0+#9<+?"..CDF9%9;A38;8C#"+82-B0#80+4//;'4&A@C>!#C%<'AB*B)'='"H5C="-3':B$@7A<-A1$8)8)/"*08H,++1*1@,2*>BGG
@r343
ACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGNATTGCCGCGTCTGCGGGTTGTAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTG
+
9'G*,!44+;',1</D-/B!"-/H1:D>*931%9&"8%)$!5?-=F<A',:$?'(2<!96-;(6#.;@07+>*!#9;89+.4;>#A05.?C9;D%A*3%@=%',<E4*)1(E9B;)7(!>D14,.9>@,%:7%G<B4H78"#B9C=F1?*%=!4$;3;#3GG196%*C4,$%BH+F@#G6D#,.%=C"4
@r344
ACCTTCGCGGCNGATATAATGGCGGTGCGTTTACAAANACAGTAATCGACGCTACGATGTGCGCCANTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAA
+
.H>H1;8/)5+'2-C)<9?,$?#+AF;A8>5;15:)+74*$95FBE15$>?'!&+FB1;8E6@!@@(#(1:E4;/*72GD/6;2$.1''*#808D--$E5B&5:<',D/C/4<&%)<-B:CEFC-EE;=#''$*8#@';6-.D5?-7+,:68&.!1#A9>G/?6C3$::<7%0,+A?98C)C71,GEE/1?1!D/(HE-)$(A0'#+!.2'/.FC3C33<*6;AH3:1D(>6H*/(3
@r345
AGAGATAATTTATCACCGCTGATGGTTATCTGTATGTTTTTTATA
+
(=*GF8**5"79%7,GF;9>0.=:#H?"H;#6%H-H+BGACB486
@r346
TTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAAC
+
/0!.5/"?"A4-.'/E<)9H$B=3H2@!6<H*'G"G3+$B7?G?D?:
@r347
GTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTA
+
6>,>!,=6)?.-(@6"<2E/@6%3!/>%'2>=*@3$>)198>@8/AD1BA<'BB1'"+C@=.+A0G.!F8"#(3"GD+9@*?&E-:3E=>-
@r348
GACAGCCGGACCGCTACCGCNCTCGTCACCACGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTACCGGAAAAACA
+
F%";246(?3=<>E32;F>+2.=E#+#F>BH"0:/4G*(:A$8.1GB>93">,GD(E*E?$$B61G3#,<56=5-D.&GE9,
@r349
GCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACGCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCNTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCAT
+
*.EE"&F,+G-'1B)>2-GE8(75D&G)5@$24EG#19&*H27!G#5A>9B-/!/*,<0"!""F$:D3@$A0=B5!3!(,>G=A9-+)!$::=+?:$$HG<-%'&7C?*96"%G0-;5.)+3GA+"4EF*:%(.%+C,4#,1*$GCD7A:49"&A##$A?H/@=!!(23A</;)*/,@G/8A<951H,CAG;)H=2D1%"C:".5!,*&/*2DC>G<;,;>(=0>A:.>#B-6H+7<775<*4*AH04(F6G0?>67>@;&@DB(C3-,+@A
@r350
AGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATCTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATNGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGT
+
0.-(:50GE,=7E2#<=@)>4&C2-<*+6>B!G/)'$?G!)#47C"0$&59"9H"GGED',@?,37ABG4B5'-8=.F8/;:#2)3(H!A,+)B(%,1/."7*5.9&6C0/*"2!H+G3.C*4FA'GD1BF!?E7;(GB'!#E8*HB9/A,3'G:7<8.5.H0&-
@r351
NCCANCCGNTGACNCAGTTNANCCGNNCGCANNNACANGCGCNAGNNNNAGACTNGNNNGCNNNCNCNNGTTGANNNGGNGCNNNNNTTNTNANNGTNNNCNAGACNATNNCGNATAAGNGCACNTCATNNNTCNTNTGNNANAATGGNGCATN
+
""$$"$##$$"!$!$#$##"$"!""#"$#$$!"$"$"!$"!$#!!""##$$!"#"!""#"#"!!$#"$!#"#$"!$#!"$"#"!!##!""#$#!#"#$##$#$"$!#$"##$$##$"#"!""#$#"#$#!$$"$!!!#$"!#"!$$$$!"###!
@r352
TCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGTCCATGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGA
+
A-2/4/13?-B.H4G3G*G*0",9682AE4>+7G<'D)0/6%1;C,E4,H?+*D2&C/AD-G5(!,E.G",*"<"+?)5,126&*5@)%.':80)G%6+FG@4DC--?@D$5$*.@44:;*041.
@r353
TGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTG
+
+B6:3=%B=!=65-D$#/G7E6AH6*&"C&4H4"*;./10;@4/2H=20H+7>F(F)CA9:.=A!=25-9D#0&?2&;?*0%@,;HH72B:$'B;:3-A)#F3/7
@r354
ACGCTCCTGNCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTGTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGANCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCC
+
+&#)$("(#*!&)+!$)&"*+#'&%%''#'!$"$&(+)$)+))#)#!&')$+!#'!$!$(*'"+!!*+!*+$((*'+$%&'!%)!"'")+&+(!$'"'$"#$&($"%($)(%))'(*$"*#!##*)*&%+!*&''(**#&$'##&+!+$%"%$!%&(&!%(&($"%&+**!#*%#%''"!!%%&)(!#$#*+('*)'"!"**#($#%&(%&&(#"&!$)#('(&%)$!&!+("#($$#!('$#%&()&((("
@r355
NCCCTGCATTCGCTAATCAGTGGTGGTGCTCACCAGAGTGTGGAACCAAGATAGC
+
*:*0"+"*/()*)34!'A:(C==3@-'''<&/6;7E"/'7@1<41)B9-152,#E
@r356
CGGANTTATCCGGTGATGANCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCNGCTATGACTACCNGCGCGACGATGATGCGGGCTTGTGGAGTTCNGCCGATCTGACTTATGTCATTACCTATNAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGANAGGTGCCGGGACCACCCTGTGGGTT
+
*$*$!)+&$)$+*'&&'+"+'$#&'()%$(#*&('*+!'(#"!%&)#+"(%'('(+)!+&!"&)#$%'*'!#'#+'%'%'"'*!$+%%#'$+"%!&"!%$$!$#)$(#*&$(+#&)"%$+%(*$"+'!!)+!#$#")+%$#!+&+#'+%)'&$"#$*+(%!*&%%***)#!("+%$%!($*"'#!(!+*!)('(((+#'!"'$!"+)(!!+
@r357
AGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTG
+
"=(+F.72C3(-8?4=0BG&E?-?@834@C%@9C@3(!$2AH..H:5<9@@$7)<(;4>@
@r358
TGGTGCAGCAACCAACAAGAAAACACTGGCAGATTAAGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAA
+
;;4<HG4(7:"0G6:."$H)F>C60E?9!'&F4C1'99GC;!@/:+15$/+'+@>%:F"=2F)'%FC)EEE,;&C@@GF!%:61=/$@@1:DE.075H7G!C:,7=.<<C'FF9&$G4E8%((5?FH%#*/9"./(,-/"CC3,-*
@r359
NGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCANCGTCGGCGCAGAAGGGCTTCGCCATGTACCGT
+
&<G7E6<@('AD8$?/=#.8%G/=&="F4C:9(*(2!$)FGE1+*>BHG;.:C(G::">GB&7)D%6"4,#E40>&4C:.8+))7+3,>!1.,;(3*7'/-$)>/3/
@r360
NAGNATNCTNACCNTTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGTCGCTCACGGTGATGGTCATACCANTGACCGACACGGTGGCTTTTGTTTTATCCGCATACACCGCACGAAAGCTCTTGGCGGTTACGCCCTCCGGCTGGAAGGCCACGGCCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGC
+
$#*('"#%'""*"!+&!")*)$$$()*"&#%%'))+%!!'$%+%*((!!(#%#*'&#%"(&%))'#&(+!$)%*&)"#&"%)&)$*)%%#'+$'($%!%&$(*+!+&&+(#$$")+!+!'+#'!)!&*)(&(+*%)(#(##$*$$#!*""%*!#+(#)'!(++"+*%*%)*!%''&!'())&#('!(%##'%%)&($""'*%!%&+**$+%*$'#(('""*("%+(!!#
@r361
NCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTG
+
#=+06;9&6.,C%265<>D#@2<51&?1G5*A7%6<4?G("#*B3BH/"C:F;HB31&4>*%8AF1.?&?$$)B
@r362
AACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTAACGGTCGAGCGTCAGCGTCCG
+
7-5$(6/"G(8=F6%6DG"3EB'27'8B90)9G3E%1D!*C@/FH)GB7>%"-+33*E2259;$8477.E>#/3"1>1G"45B032;(?#)B;@-!<0-<HE240("AB*+49C*3!=;(,*08>A+'?//6BC,$/,'H#/3B,?2$*%A>!
@r363
TNCTGATGCAGAAAGCGGCAGGGCGTGCCGGNGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCGCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGGTGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGNCATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAG
+
'+%+*((&((&+#++"*+$+#*"""%+)'&%$#!($)%&!#!&!#)!"#()&'!'''#$$%'$+%!""!"$+($"'))+"!'&!$'(+!*!$*(*&*('!**)#$)!"'"%+&&+#+++'))%"%*&*'+(*$!*$+"+!&#%('%"%!((#!+!)$((')$!***$)!!!#%"*(&!*)(##&''%$+**++&+#"(($"#*(+$%&+$'++*+)+"(%$#"##((**#+#$#%'&"&#"'&!)"$"))#'"#$!'
@r364
TGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAANCCATTCCNGGCATT
+
?FG)>+119H)(0'73GAF+?<!%C%4-B.=BF0,'>%4<9@>69B$1!G'C-
@r365
TACNCTTGCNNATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTNCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCANCANANTCTAGATCCCTCTGAAAA
+
!'*!""(&('$"%*$%(+)"%"%!#!#(%#++*%&!+%*')($"+$!()'$"'*)&&+#%#%')!'&&(+!"#($"!#&!$&$&*%#%#"'(**!**&%!(*&%#&!'(+$$'$)&!%+&(+&&"#!(!'""*(&&&"+'(&("+##+*
@r366
TACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCC
+
3H8F9B&HA&E'$89A&#!$B0=<H)*38-5*!&8!=B5;&-922%A6B=<G3,*;0C1+:9G)>%:H"1.:/A)19%?/((F>!>6#3EEB#53;BG78G#@#'9$$8%%9,9D<?GB4)5)96F5
@r367
TNGNTACGAAATGATTCNNTCANCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTGCCTCCNGTGATT
+
)!'#$'(%$(*#&'&!(""'%(!'%&*+((""!%*)*++##)!(#%())(!!("*"&*+&+!&$'!!%(()"*'($"*!$)$*)'%(("$(+!)#
@r368
AAAATATTACTTCAAATCGTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGNAGGTTTTACCAATGGCTCAGGTTGCCA
+
3?%F%8)/'=G$756(36;4-.@,G=C+.0)?(6:F+>$;H5C!B/3:B)2D*,4.6??A:H8>:-9.0;1AH%%*@9F#&#B&)3),>'G=-294D97",'F=?CB3D>3.C@>ED4#1.*#;&<G=.H94!C>*)D!C0<1(?/'4@A3":D*"4369F*&?+'(+'E;G:#8=94C:%."C=8BFC+/%483><>(+9A,7EE@A6'#,9,G)7"4=7&G)"5GC6C;:;*?2):E+*.$:%6!0%6%5*=//.;''$'*8
@r369
GGAACAGCCCATGTTTTTTCGAGCGTTCATACACCATGGTGGGG
+
0"/:-4+GA/*'?+C&DH"8AG&5'F2+8%C,9'"@%$=-#'?;
@r370
ATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAAGTTGCTTATGGAGTAATCTTTTAATTTTA
+
:3<2D,D-=30=/;,*H+,A$:#H(7$>,.39;1<243AG5EC4F:<9:%:$;E$E%,52?H:&#*05@:3:8'50*<;2B>*'5E@/#0$/3"F(-),"'72C
@r371
CTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACNCGTTATCTTNGTA
+
@8!163F')<;38.$3/>.$(589>F-)-B+"F#!F;.,!#HAA*7E9>:%=5*"7"38%,-BB/
@r372
AGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAACCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAANACACTATTACANAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGAC
+
7G<#%1!/$8=>/9,95!F82F3!5//69!?CA;;@-)B?F:)1$G?'945=1A&)F,G<1'!"A.(#+$/"+C$F=CCF5D*;9)&*6(7;9"#HG60B%DH&HC(%)/:0C@/H4GDD$A=6FA7)27(6*"?D;8G%*6,#?7B?">$!1,F*-?%?'D<,)5B='(($0'B!H.7)E?%*A1#7294A71-2:G?==,@*"$B"7*0"?F,E=121%>H+H
@r373
CTAAGGNTNTGCTGAANACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCC
+
!%)$'("(+&+*"(&')$&!(*(&#(&*'%+$&""$(+(+')#)!$!+("%'!&$&+"&*"('+)#'#&"'!'
@r374
TTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACG
+
$$9>,B().4*16*:'C(#E&/'*B(H%09:C,;G!!&/0(H!">C3%7G4E8B/A$&F#G$#@?8&,2D19D>A=B>86C"-+*?@"=G"*G0*</AABG>F
@r375
CGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGT
+
"/DA6!37B):D;%D0>;/4'--DB*#>*:.@1;86CFH*,D;.;#BF:/3B*F&=8:BD=0$<!&?4
@r376
ATTTTCAGCGANCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGANCCTGAAGATGAT
+
$87E@85#.<F/9"G2)"=G:"7&&>=5=(C3:#0@#:0G.=?@?&=D06822,*3()B,3&&0"8D(B"59(FA-?"G(H
@r377
CATGGGNTTAAGTGGTCAGNCGAAGCGAGACTGGCTCTGGAGTGGAANGCGAGNTGGGGAGACAGGGCT
+
%$')("++"*%$%!$$%(""&%%#(+$#*&!#*%(""*#)#*%(('&+++"(%+(+"%&!"**')(#)!
@r378
ATCTNACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAANACCTATGGGTGGAAT
+
0"451E:DB5)9<(,'-.7>3!GA;28-"-$8)FA)!+71"A"&'&/58")>.F"5*61>$B
@r379
NCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACA
+
$+%%"+%$&+&"!*#%%#!"($"!#"+!&%#+(!")'!)((%*($"'+!)**+*"+%#"$!!"$#"&
@r380
CTGCATTTCTGCCTGCAGCCAGTCTTACGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACG
+
3()623)HH'84$-#?G%*+;"+7%6.>DF-$2:@DC/AG#B417B$#-;HCH:2+(=/E"@E2382<++-@
@r381
GGGAAAACTGANGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTNGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGNGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGC
+
&(70+6=/,F!5!1&!-)$2B?*H/.&4#!70,#A>/0B-&-%):G<'2'B$=+9.G6.%<$H9*H&CH;6*$3E%*;D24EG"+/<1%FF4F/FH.*/-%H2HGA5,>&<9;=HF3F*?BG&?3B"27C"0.,8>2G@D>3.2761<A%7"E,D?!.)1;6F>(1>=>=D15E";#:GG$0?>=5&?,;C74B@&(B/'!27%9$B84D9,4!!3<:GD=7H$>:!F7E8$FE%/,:*.:,2"
@r382
NGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCGTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTGTCCGCNTCACCTTTGGTAAAG
+
#'*'#$+*&*!)!'"&(!&+)$*+#))$*!($)!'("&+&"(!+)()$'*(%"+)(""+"&(%+*+#)#*)(#'*(%$$#$($()%$#+!!&''##"#"%#('('(*('$$+!'##*'*$&"%!&*"$%$&###$!#**#*&''((!+$
@r383
TGCTCGGAGGAATGCCTTATTTTTTTCTACTGCNGNAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTNAAATAACCGCAATTTATTTGGCGG
+
?H%,3%9#<A;*"&!B=GHH#A*&+/E2E=8E</7++/$-9/46B7,%7=0.0</9<=5E1=F1%:0%H-!<).;;G;"-G,3#-1H);$4">A+>*"",*C$A%BE9#1:E!)&@48-/"
@r384
ACNNTATTNGAGATAANACNGTAACAAGCAACAGGCNGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATG
+
*")#*&)("&*(!**&!*$$&&*+*+!&!'&"$)#$##$!"#"$++!"%(%("&*%(('''&"!##!*(*"'!$'(!"*+"*"+&!$+!++$!+"""'###"!"'
@r385
NNNNANNATANGTGATANNTGGCNGCNAANNNCNNNTGNGCNNNCCNCTCT
+
$"#""#$"$!!!$$#"$!"$!$!$!#"#$$!!"#!#$!!!!!##$$""""$
@r386
CNATNGCNNNGNCNGNTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATAT
+
$''$$"!%&#("*##(+"*"*+++#!'#+)(!++*&(('#""!*!)#((!'+*#()*&$+*$'+)"+!%)(#)*$&!*)"!+'###!#+'"#)&("&&*+(&(#)'"+'&#"!(#"*'&++++)%%()*)#!$*'*+$"
@r387
TCNTTCATCNNTNCAGCCCNGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCNTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTGTTAGCCACCGGATAT
+
(*%#((*$'!&('*#*(#&"*&+#$+'!"*+!!&%""+%+#%!#'''#+""#')$')%#*$*%#"%*'&%!"!+("&(%&()"$+)*'(')#*%$+)+%%$&&&$&"'+)$%$$!&%!*!+&+&)*$!*&)#)('++)##(!'()*!'+"$'(++(%$"+%$$+#*#$
@r388
GCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCA
+
993&5&H?B3!(6672>/F6?*+4380A!)11?@D'%;G!+BFFC-A2EG
@r389
TTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCNTGCTCCACTCCGTGCCGTCGGACTGCGTGNTGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGNTCG
+
?>D@8@?B=<)CD3!&F'2D,:DGA$F?#A88>E)C(G247>?4!;DA:G?,>>7*DC0G)13B#*2D2."-/>370"B:)?+6#'A1==<-&)48#@83+5B=-@7$&1%F;-B
@r390
CAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTAT
+
.4@4D"?.D$/#'7"20&%;5%F)F,4/48&HC-#G95G!>:448165F.&<4)82CH?9!?*03.9C=99'7)4-;@*:G:.(A?%3;#>!-+4D,
@r391
CAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACGTCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAAT
+
<GB/F4+9=.5.569;CD.63*187;;8C?=%4=E3+3':@$,'=@6')2E7*4*!*9?F>EHHGA)<6.'-8".:7'4.<5,!@!E+"8=("*.?B@@90'639E<6,958'##3=1DB%GH.-B'&='B=+<!*<4?34"8$
@r392
CTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATC
+
32/'0<4?A8.;.29B5*0@<B+7>H1!4:H+2A=H<20:D+7A96C$!GG"6<FC:)9,#)770$C+'$$DHG7/A3D0
@r393
NATNGANGAATTACAGCNACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCA
+
$#*'+""$&)$'#+!$!$#(#%#((+$'##*+"'$((&%($%+"$#"%#+%#('!!&$$%#&#!+*
@r394
GTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTAT
+
'>AE(1&1;<,-:'7-"!+!"8A$=F#)C4@*?.A)0.;"!-?8%+4"@<
@r395
TATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGN
+
7@:1B(F&;6!.!<.*E,96*=7<D*;>!$&(?/91F/-2'%26')8G")3H*'0!
@r396
CGCCGCTGTTTTTGCGNCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCT
+
C4?9+4",8C>C?@(5AD,F3G$.$5C9@&$16F=30:-"61>09**1#9;$C,9%:47-74<7F-.5%F@F/F
@r397
NTTAGCCTGCGGGCAAAAGATGAGGCCGGAGATNTTTTAACTGAACATTATCTATCAGAAAAAGGCCATCTCTNAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAA
+
";%-><9,D-5!@=/B*H-G</:01(=@@E:1+*BG.$&#C"GA736#E:B7".A::'DH%F2>!F18E;-;%?.?0(*!>1D+2E#6,E+;E$1(:4(5#=!'B%F@!<CB8&8F'/4<,8AA+7#15(9834?5&9*1,<?(E
@r398
GCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTG
+
%=B("&:',?*9=%1C";09:$A$/>%?,#!2(1'%D)$&HAD%55,='@651@;29D(C/1
@r399
ATTGCTATAAGCAGAGCATGTTGCGCCAGCANGATTAATACAGCATTTGATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTCCCTCTGTCATTACGTCATGGTCGATTTCAAT
+
A9,1,(6);?8E8?564)=-G9FHFE;",,/CG$.4$<D8%-<8-CA0/.434.7>6=>0A7(2.E3!-"H'4,;#;&8C76F%-%.1498&7G*&B):=14D."<:):1:1/@HHB'18A:,-G=A8D'3>DB>.,C9/#%A:H$9:@
@r400
CCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGA
+
>4F61"7G7$A,+-@BA.D7>4@&E6&#80CD5:+8("FGD1<@9=C!&#2#+,D9$7/C;%H"<+?B60HD@(>C18
@r401
CGNCAGCAGGAGCTGGACTTTACTGATGCCCGNNATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCANTCTCTGGTTTTCGTCATACNGTGAAGAGATTGAGCCACCNGCCAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGNCAAAGACTGTATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAA
+
*));.>+@4D?@G(1B)F.68(*00!%(;0?=&@>C0622(=1B7!%#0?>4'"=;,+'6!F8B@.$:*81;F>D,"5//B<7H7G)H7-F9D.)B>*'=,#4:0)H9B(4@$+-$6!/+8D#)C0<B0)&B02#E%-&2%=,!A*4&:+?0H/G%%#&<E*5&#,%3/#27+"(/E.C1#=3<#,(0!+G0/.>;"!.,&+,FC-A$>@70C.01:G1<;,<D0GBB,
@r402
TCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTT
+
*A"3%C:&;$G(56!DD!9#9-?BGBD&-26H5;>3<!B3#*'$%=?<DB(*<&4;@&9DE28$)F8:<2
@r403
TNCANANAGCTCTGAACCAGGGGAANGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTNTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATC
+
)!&(%)&*)+'!"'!%%"""+(+)'(!*((&(*&!%*)("%()!('+'*+$)**'%"$(++!#$))"*%#(&$%#!!$*'##)+'*)"(*"#%&*+'&!"$&!"*'"'+(%)*('#*($+$)&*#&)+*!$+&+$##%*'$)'"%)%"+#"""!#"$($)")#
@r404
TTGCCAGNATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGAT
+
4/<5*52.!E5FCAF%4:G)((C!/""(D=*$%;F38F%EC$$F/)&;26&>44)-4+H!5.,
@r405
NAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTG
+
'6C,*$)>#BH<91>,?9HCCA?!7&>%%""+4.-89*H94**(;8:18>&%C"+H$215"296/(4G)$)68$9'>;-:
@r406
NNANTNCNTTCCNATNCNANATNNGNNNCANATNGGNNNNCTATANAGNGGTCAGNCNNNANNNACGGNNNNNCTNGNNACTACTGNNNNNC
+
##$!$!$#$#""$!!!#$$!$$$$!$#$$"!$"#"!!!#$#!"!"#$"#$#$$"#!"""!!#!"###$"$###!""#!!$$###"!#!!$$$
@r407
ACGAAACGCCGTTCCCGGCAGCACANATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCA
+
.%$(C.-D'5?/>EE'G1>2$E?8*+0&$H6F!"6,70";!<-021*;A:8=4(&+@084B
@r408
CGTNNTNNNGNTTAANCNATNCNGTNGNNTNTGNNNNNNNNNNNNNNGNNAGTNNNTCANNNNTNAGATGGNNNNNATAACNGGNNNNGCGANNGACNCCNTANANAANNCNGTNNNNCCTTTCN
+
!"$!$"#$$$!"#$!##!##$!""$$#"!"##!"!!!##!#!""!!!$!$!$"$!!#"""$"!#$"""#$$!!#$!!$!#$##!#$$"#$!!""$$#$$"#$!""!""$!#"$$!"!#"###"$!
@r409
GGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGNGCAGACCNGCATGTCACAGCGACGCAGGGGACCTGCAGGATTTTAT
+
>3H>09'!6<!'(833DE8)+>36=5$B,@<%'&B3.=6"?D8;@&E42/%*,+4")4D$G@#<:;5,8@5!&&*D65*>&62*A4:7B3E#>E1HA8%)8A)
@r410
CTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTC
+
3'C4"5,'</,2E3/!<A2@GB/.$HC@#.57C67:<**&
@r411
CCAAAATGCTGCTGGGTGTTTATGCCTACTTTNTAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCNGAGAACTTT
+
"0#*).:./@H!<A2@<1@G0?(A2@4;DA&'78"E'&F%2!1$$#$)G74<=C<3.,-1D"+-95G'-:.9=&C.$-0A&%-3D/3A;!9.3G:
@r412
TTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAG
+
ED?'0H)C6A.A&?.GC1:DF-:7%74:<46%=#==%<F8*
@r413
NGAAACGCNTCTTCAGAAGCCTGAAGAGCTAATCGTTCNGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATATCAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAA
+
0B7=5+%.2HFC9;E/999?G7&FG),#(B)DF1'4F40!/;F.E:7+/4A?/,)/2:*<,<8;F)CD"?G7+G296?F2:$9'C:46G:-12BG:)D0'-@#FG<=3;)49=8%:&D7(*/?>7CE;:?82@$:%79(-)D8@-,$
@r414
CTANTTTTCTTTNNCGTAATCGAGATTAAANNACCAGCCACCGCAATTAAGCAGCTAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGGACAGCTCTGAA
+
&"%"#*)%(*$##%+'$'#!)"%"!%'''+!"&&&&(!#(*$&**!!%*'#$(%*&"!)($#))#+$*%"!)(+'''&(+($"!)"!!&&$#%$*)!"&+*"&**&)"$+!*"!'(##%)%*)"(&)&(
@r415
ATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAAT
+
H:F&0,</C2917-#)G%+<80-7('F$54<0AD6(<>$/#$.E)F$D/8$B$%H=9861D"(7EGF3.C89F@)EF+61478E1:0FC/>AA/2"11&7>;E/<5?+56>(/A8-3.!1>"!DBD
@r416
NTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGAT
+
%,/+4"4$+&02).',#C)?3:H*%<08*"$E!AG<E%/-(?5#
@r417
CGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGNGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCANGTTTACCAGTCCCGGAATTTGTGAGAGATAAGACTTTCTCCGTGGTGAAGGGATAGCTCTACACGGAAAAAG
+
B,3>B;C*/&&9<;!#FEC%'8FF-&">E@C!G="7)1,118&5$2A"9?5/1(!,"%7)-B@=37(32=+E?#F)2F2>(6E,+4F7:;<6F%#:*4D3<*@*D<97"),=/D+A!%<A+#;/*#@B=;@5AC4#-B37/=('0=E,<&1(G%-":F6?"2@)A0?8!-/A/8!':$G*>?%H>;0;.>->;;*?(06/H;37#-/9)2?81D8&2!(H.%("<B(5/@=<D.55CH<;.<8DG,>C?@*/?F)/
@r418
AGGCGAAGTCATGAGCGNCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTANAGGGACCNAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAG
+
&+6*1)"49=2*68A:"),66$!2F'/%HA9'0)2':'=0CA=98C#&1D4=@CDCB&)B?.G?H.EC1??!1EGC0DC(455!FH8;?22B(>@$-@/#C?468-8%>'%'G$*B>0B=(>,,:F*==-&'?%G<*4<-8GD)3'48F(%&/D6,07,/F'@1(3"F'6D;<C,('3.4362!&30
@r419
NAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACA
+
-0$/!AG*90/B.+4F/&=?'2=033:7=@;,!G53F!GD<?3!<>##CG3;6?4CG'<":+'/:D(H98!!D/F9B<)+!DCB,9A9('%)9"0
@r420
AGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCG
+
!D>#E90G%#4:(-=(7#!03-AC,+)8G:97:&-4#)E/+-B<B00C2!"/5'(A9F%FH*%
@r421
CGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGTCTGANTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGA
+
0+*94@1(5:?<2C!G;-"4/B"*91)2D6B$5C.5?-+>B8DF37".E5,*</<A=-DG303D>C+G!84@D*:=E,G@1:%:%B;<(=00@@$,9#1(."!=,77>:'@&?""H>9-@&>E3C>()EC=@6"
@r422
TGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGG
+
/>4*6C4@/5F@A35,4C/+,6%C%<2CC>E7%H@8"#8>*9;C0)(7D*04;4'H%#4<2-03"HC",*)&E7GHDB@E*>B>6F6(?9$0H6>6$+76=4-+1<??E:?+2"@,+015#"3">;##@;D.>2A=9
@r423
TAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTNGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAAT
+
AB!;%BD)AD/$#@,7"$A0A-#43>1<;.!+;3GE8+)3,+=<9+304-F&D3D/2"6!:-;2##%<@F*1E'%"3.A'0@C2-D#@9CFF%0"+?;*8G+9:%:#H->3,3E.D4!5/BE3;(16BF;#?
@r424
NGGGCCAAGTCAGGTGGNGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGC
+
"2%C<2508?!8C!(5AB42!,(#8:EG&@6D0.@633C!'6'4:/-<(,3#/5:'CG05026!?$/?E.EG95F-*:@(<%7"59>D$HGFB@&009GCH99&4C4<'GC1-A*&&8D:'=:>.+<@#:!$/&'0E>@*3?;/9"'/77&&&F:)7)5-21@>"?*=B#$E$974.E
@r425
CCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCT
+
;8-%-;9*F!6C0#!E$B&D%9&,,6+#B,E20:+E+!$;6<@)@0G("(=%9'?1->0$:A;B9G9/+C)#H.HD-,/=>A!H*$:7!DF7G%
@r426
CGACTGTGAGCCACTCCGGCCATGGCGTACCCACTGACCTGCTTACTGATTTNTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTT
+
D&>12#</4"!+FC'#1C22%A%/7*@'/%.@.C3-),<*C<8)4CA>>.=:24<*9%%)2<<!G*@/%FG9B&?=7@!04AB@CA$BA$D/',4==@B77>188(8.%3+B<.F"6)6*=14>25$<&@-6>>GB''(263B(
@r427
ATCCTCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAANGTATGTCAGGTGCGATGAATC
+
($!)&('+&%!"!'")$)&'*#&&(&%*'*'"(*))(((#("%%)+("%(!!)'"!""(!)+&%"%*$$
@r428
GTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACNGGCGCTGAATAATGCTCTTT
+
*>2=?9>.G5H@<,0361#6B$/6B@(2E*/=2,1C*4;@@?G"(A($6H6F*H2-&/#D
@r429
TATCCTCAATAGGGAANAATATATGCTTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTC
+
1?$4((0.$583&(5&9,;<E.B$0E0%-+>"+%<2GFD897$;89695G3>?9;H*G:==91*#246)"29+A"#E?;
@r430
CACACATGTCGCGGTGGTTACGTCCGTCACNTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTC
+
:::D)<9;5#-%B1%+B8&B3,#.?"#1+"8A))94#1E=60C6335(-9;@")96$1:1C##,&9BD;8**0!
@r431
TCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCTCCGATCTGACAGATTT
+
/1E8);8!5)'58961*93G;"-34=1.)9?4@1D5.%;G<!D$=0!,G7<G0G*E6H%7(9%,%;
@r432
TCCGNGCTGACGTACACCGTGCTCAGACTGTTTTTCAGCGATCCGGATATGCATCCG
+
E*,E4=%E6!8CH5?H0(%%H6362BH*#1!0')24;*)4C:-2!=<#!&D*A$7(3
@r433
ATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTC
+
3F93),9GCB7?7(D@<,9)."H:?97@-3F0DF<?D.6AF!5,0B8A9"A&<$8=&49F3'?-,(D7AD58-:#20:G.(C?%((1(((-9,-:F:5*#8/*H/,$,2&65@)$><8D@-B3(-<%1"G>,)G*A:8*9C#B6@HD8(:-%"7(<,B(1(6<8,F3%-<,H<!8C%+A<@!?8%.''6%,A,=@-;5&1%%7.1.6,6%,!+:F
@r434
CGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCC
+
>@.2A>&4B!,'9G+5:0D?<G6*B.B77;B.!/C.().3G42&E%6
@r435
CCTTTTAAAACATTCCAGTATATCACTNTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTATTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCT
+
/>(5:+3C5>#*DD3D*'=.739?%"$"GC,/<(=&FD-7<;A24&7%+7;?6D3=%"BFC,00'/9*F#&<8+0.+7"D'24?1)-15!;E:4"&"+3A>*(:<=C$,4H,:5;@.G3)AFC<&C/.,<4;!=F&/$>=*B7@F&=5@;!'.(6+,).<2()>A-;%4)D!C-*!!$9:.CCG?,19F*3*6"4/""5D5;.3<'87.:F>.?A/*'/"C9EE810#="H")#?A%"7<0%($8-F1,B,'B8!'223(@1#!68?EA+5C99>696FC44?49-"!A=!3;?551=HF-+<1%
@r436
NANCNAGNGCNNCNNNCNNNTCAGGGNNGGANNNGNANNGGNCTANCNGTATGC
+
!!!"$!#"#"!#""!"!!$$!##"#$#!"$#"""!$#$!"$!#"!!##$#$""!
@r437
CTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACG
+
8>&6B</'A,(++(B<F7#E>=E+@'H$FB0A7@";:;CF$")*6?".!#=2>:FH@)'1"8G751'CG@$3-047?6:?,38;)B-'9=C
@r438
GGCAATTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCC
+
)&%##!+('%&%$"###+$)&$)!"$$""&*')("**&(&$)%&&!+()$&$#$&"#&)(%"
@r439
NTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTNATCTCCTTACCTCTGATTTNGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGANTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATC
+
$%+')#'&%#("&"$(*&#(!&'%''*+(#""$(%+(#'!%!%*#)&&*$+++++*+%%&!+"%!(%#$%($*+(!#()!#*()''''"!'#(*)$)'+##$*#)*"(&%''!%$*'"''!('!+))!+)+&#'&'!#)()+'("+#%)&!*%*'#*&++'")($%#+"&&#!*)#%(&!*&
@r440
NTGTCGCGGNGAAATATCTGGGAACAGAGCGGCAATAAGT
+
%C*@!17D##&-F?>;'1D4/&:#4:4?,#!&?F!)'>B,
@r441
NGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGNCGGNCACACTGAATCATGGCTTTATGACGTANCATCCGTTTGGGATGCGACTGCCACGGCC
+
%1G4F8?8@"=!)2369;?2@*0=4-5.B7@.'&)2*'H<@:A?81>F$#E?>1B8)55<<6:;/GA34<>F(;$*35?)48,"8FH/E#1%/.:96==;B84;96;$G"860;8-;
@r442
TNATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGC
+
04D3&D.2A+6EH!?-;*'&?G-,@5)0?<&"BH/$3$!5;D784=%2A#"7+=728(2&7?7'&0DAB!%CEA=/!/4<">:B7&*)4:6>F:3A.C#7/5*/"2F&211H)'0'"A=*+$*G1346'%
@r443
TGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTNTCGGTGCCAGTATGGTGCTC
+
50(4>4<&7;8(=-3".)@'@+<E4C?>6GE!!=5'0B8>03,%9@1D7="=*#G?1?>/*#7.2#B$8:)B15,3
@r444
GAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTNAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACT
+
)6F0)+0>=.*/&&)E'$6$);20/%!H9)340=@;)"3"5;0);!FC!9(>22B;7B!62,DF>E/+-$><AF=';0F55>$,=HG@,8G,'HF"D*650),$G"9BB-
@r445
CAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCA
+
A(6,A(G3;/4'+B=5+@8$,B3E87$(#3:(F=/3??!03211+*)H:!528""7#'FH#*
@r446
TGGATTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCTTCAATGCATTAAATGCTTATAACGCCGCATTNCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCC
+
':=18/;=D2'?.=2/4(7HF12H<F7#%'?;G!"+:-A4.4/0C>.!/!$7)D#:H&/<7A&0D""/3%+"@%E!(@A)$#FC'&0?:!*6,+4;84"B!"E).,;>7/C(?/&B2+;*D7%<F%D>'$G5?D5@.27)#$-=G=
@r447
GGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCAT
+
6(FG)5(@!A<#):7/#0764D6?>$/%A549&$&.$)2>EEB,!E'2#"4E4GE*'0,8%
@r448
TGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAANCGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAATCTNTGGTTTTGTGCGCAGCCCTTATTGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTNGGTGTGT
+
7$,21G7G4&HA?'89:94#H?&@"(/A(/DBG/*1E"69*?(9@;0:02/.!/E-/-6.9"::5>8>H.&G22=9*(G-0:HF-+DG<>1!.1C.91B+(545G-?E,$";?F-!5%$('<93$#10&-)8B/<!=;>5F*DD/";"/,2E%&<BD<)*@15*:*%!@71D'8/6F!G+=%3-D%#G??>A!11?:G(H@0,<B(>3+:A
@r449
GTTGGCTAACGATATCNGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTG
+
))#C+F3;/F60@AB(6+,G7=04!$<>4,?939/>A9<;(%)?1A6,C/=;<#?<-3E?7D-??(GCC(@HF<*A(:<.,=(#-0>G1"2,@$(4
@r450
NTGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCT
+
4%3B=!>7.F@7*C-<561E0?FB&*+(F4&G8+>8*'&,F,2A:#D1!/%($A>72+;1!?-2HD<B=/:&9DG$8;,G(7=!F"H8.#35=@"4F1/4E@C*>DG0=8;6#*6DC2$D1(G.33:
@r451
CCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGGGGGCGGTGTATGACATGGCCCNCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCAGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTTTTCTCAGCGAGCGGCTGCCGGCCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACG
+
+!#)$#%!&!"%(**)%'#+!"((&%*'$+')+")()%%+&%%')&#*&!!#%+*!!#'%""+!(&('+'+)%+!&#*%%%')'$#+%%&+)!))$!++#"+#!#+%'""'"'(#*(''()%%#"+!*!!*&&&&('%+*%)$$*#(!&"%$$'#($+*!)&&%!"(((%%"+&*'#!&#!$+"+($#%(+(%'+(%#)%*%(%"')+$)""%!%+)%$!+(##"!)(&)!%#+%+*%)"#'#+''*)#+*+#))*")*")*($%$"'*"+'(+!#!&$!$"''#$!""("!#(+'(')((!$%$(#+($'##*&)+&"(*&$*($&*(!%&()
@r452
NCNNNTGNNNCCAGGNNNNNANANTNCCGGGANCNNGACGGTNGATANANGGGCCNNTNGGNNNGANNGNNGCNCGCNATNNNGTANNNGANGTNGGCNNCGNTTAANAGNNCNGGACNGNNCNANNNNNNGNTATNCCGCNCAACNNANNNAANGNTCNNNANNT
+
""$$"!"!##!#"#$"!$!"$"$$!"#""$"!!"$##!##!$!#$!!$"$$$#!#!!"#$$$##!#""$!!"!""#!$##!!"!!#!!$"#"!"##!#!#$$!""""!$#!""!#$$$#$!$"!$#!""$""$$$"!"#""!###!!!$!#!"!!!!#$!"#"#!!
@r453
AATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAG
+
0D>:=?"#9F0/3+"=:!2G<"9&>?"*'"7&-4<;;C+/@9F)ACE)<77A#D(7&*(F!H!(=6AB"#+@E27''G+-$*&46;##9%D)'250D:6#CC$4(4<B!#-(=#"':-9(<-GAB5G-+?B$)3
@r454
GGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATG
+
ADA#9,+C8.A58*/8!>?*C!CD7*D<8E+A5-AF21/7*GD*,<6'D?A(;.,1?9*7)+CG4111B?=8"FA3@7&+?G.0??'76')F0#&:F"EF55+0)>G1G@+B0!<4&(C9<+!:+
@r455
NTATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTNTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGGAGATAAAT
+
):8:A,A@,.C@BH63D47A0<H=B'F0C0"'4A087!H9C&1?6;"GD5?GB*&@B(46;8)86+D;>(8-C6#<5$5,*3F<E'0'"G'+-0;&F'%9&2'E;7&)*-."-A83A%=FDDEB5HF%0%67?3CG?")-?8+=!AC/?3=2=7'C5CH/:?%#66<*%28&E2&E;(!D742E3A)>6(&+9#<"<*
@r456
NGNATGCGGTCANAAGTTAGCAGCATGATTGCCACGGATGGC
+
!''+(*++!&"%(&&"$("+#+&"!+*)%$(""+"&''&)*$
@r457
ATAAAAAACGCCNGGCGGCAACCGAGCGTTCTGAACAAATCCAGACGGAGTTCTGAGGTCATTACTGGATCTAT
+
<%:8564C'";;**,=$;:HB=91-@7=/D*/>A)A#?H/53DB2-F:8G,#?,2GFA2-<"$&9@G3?$,%16
@r458
AGAAAACTCTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTT
+
8HH#A*>5%7F4"=>2.@2&E8@&D)5H'5*>&8",;?C+.90GE/-<CH-G>F3F@5825*.'!C&5>.D-D$EC*,F0.45@!.B2C2F.G/)75*A?:=2245B*;692'7@%"6:-#2/=A"/"G.)69,1@%05$B1G';+<4,.
@r459
CGNCACNNGNNAAAGGTAGGCGGATCCCCTTCGAAANNAAG
+
(&!(#)!(%#+!!!*')&"*%!!+')!"$'(#)(#)%"&'!
@r460
CTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACGGTGTTCACCACCACCGTGGTGC
+
%.C%$.D>3-E086.>):41;<:):A.3:C.G*E+FC8"&E*H@D''>2H08?B-953?+/8@>1-D;32;&812=>G>35*D
@r461
AGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACNCCAATAAACCAATACATNCAATGCCA
+
0F)#H#7/A=!H40<'?'>1)G$3C!E0+-8C'@#6!1DC7&#1#;)/4(.)-#:3;D;1"B/7-B:2',<C+?,C,2!*C=HFC/,$$)E(/G9</
@r462
TCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCA
+
,,59=B6*G4"8*A+4;A/DF+)B49B2/"-"07@'2/32$59;#5455$B;@%B3F52&CH*,2H@
@r463
CGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGG
+
35>"H=2,4&A/66592@'(C)@#.(0$29!33+>C'+D!
@r464
TGAAGAGCTAATCGNTAGGCGATACTATATATGCATTAATAGACTATATCGTTGG
+
F;:H&&&@">0/#')69,-6AD-:(%7#0)H+G48<6%/>?=>03$C-39!:'5%
@r465
CTTCTCCCTGTACCNGAATCAATGTTAGGTTNCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGA
+
F39C9#'8,,=:"@2B97>G-B1E60&//4B35":+30'/97GF#.%8=#:C#)0GC+2!)(+=)@<$!>+H46&),=062"5:C$E?4D538!-05?F(:;6FB!,4AB2
@r466
AAATGGTCAGGAAGGATGGCCTCCAATGGATGNTAGCGAAGGAATAAGAATTA
+
<"$/5&12G7&@:'??<8->B'F=0=F#E=E2!(C031%)!*H/*2;)*:CFH
@r467
NNGCTCNTGATACGTANCCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAG
+
#$EGF&46.038(1B0/">A3,'@H;/>@.B&4-">@6#.F;%<#;?)@51B8H/82'AD2..E,<C?A+07C-!"A:
@r468
ATCAGCATCTAGCACGCAACCTATCAAAATGGNGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGA
+
'6"-/$!C:#AE'4HC3D@'-&$3-20')A9+>,8B);/(@G(,+D29>C;E$18$+=19)B'&(&*;CF3GH#+
@r469
TGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAGTTTTAACATTTCCGATA
+
7+(@-D@$"='+?B%>C7D#6-7A5G0FF&B4B<BCB&/4H04>+83"B9>EDFA?;E7)FH$:D42%H*@0G0G%#6361$341#E=<2;H'-79<92GB$2*@:)'HH3126/C;?F3=E1FC&?A5&HB**BC%:EF2&$.4-8;1=7?G
@r470
NTCATCATATGCAGGAACCATGATTGCAATCCTGATTGNTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAA
+
'=)/&5=DFB4>"!,?!(BD4)/?41#,F;8H?1'A0C<D379+;#%?)A"636H>D+1D$;%*,-($'(()7;13F:3<&-4&+;$G%575-F<%<"-H*;(D1@B<7<6$H%%5H&/*FB;33+E/?<B6#8@97;=>21HG%$!EF.5*D:F"4@%G+'2;5#@%CD**2G6=76""(B(=;48@.@&42>":A3:5D<*2B.<DH7;>'$1;2??'870+"4'/8+=0B'0.<6;%/<2"$>@??%=H'.0'+%%'"H,6"4B,G$)>(E4"0"-61$97.+2,?6;>6*BG>8"A2A>;-#G?HE$!;3@(2*?!*G30HH;'8?B#/C)?09(
@r471
TGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAACTATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACA
+
>61CD$@F1&?:),;&G6":%0>""%25#CBD4&26#5"35FD:1(4!):7F#=(*;@FF=0D':)4.!74&/+?7$C0587>G25*95/A&=!.-(+"H/.GDB.C.,54;%HF$0=>C/90
@r472
TTTGCCAATCGCGGGTGGTTTTCGTTCAGGACTACAACTGCCACACACCACNAAAGCTAACTGACAGGANAATCCAGATGGATGCACAAA
+
*!+$'&''%#!''(%+#!(!"%!!'"!()$'+*!$"()*+$$*)"%+(("*)*&'+!$$'((%&%())($(+'#(%()()(%)&'"&()"
@r473
AGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACC
+
*+BDB62B:DG++$868&%#1/CD!C84D6+C//%:A&?FBH##1.$,1<A!/-64<>"7??B/G-(9%6H9.*34!';7<,-'FG=">&"E#5AH%
@r474
ACGTGTTCCTGAAGCGCCTGACGGCCCCCACCANTACCAGCNGNGGC
+
)$&$+$%!*&)+%&($#(+')(#'"$!+)$$'$&$#)+*+)!*!'*+
@r475
TCCTTTGCCGCGAGAATGNCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGA
+
GB&5+18#0F>/27?6F"<E.(*&=B<;=(D<!$4,4)!F/D:)+7>0F++9$G+?0@91-B;$1!+F4)D:1@'?63""%40FB.',3B@6E3:)6CH'?*$.F'B@5'0=90*
@r476
CNNANACANTGNCGGTNGTNNTNCTNCNNANNCTATGTNTTCTNCNNATCAGNNNNNNNGAGNGNTCANNNNANNNNNNTNNTNTTTTNNNNNTATCNCTAN
+
"##!$!##!$$"!$$$$""!"$#""!!$#"##"$$"#$!$$!"!##!$###$!"!"$$"#$#!!"!$$#!"$$""$##$#$!###!$""""!#$#$#"!"!#
@r477
GGCTTCTATCAGCATCACCGCTTNCTGAACTTCTTTCAGACC
+
6@).:B;%0$!15(,&(E7,/(@!F2;&,70FA'-)3:$7;7
@r478
TAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACC
+
F703<>4H=G8=DA(@$26B:*9A&'76"$C1%'H&=&?+($G&//.
@r479
TAGTACAGACAAAAAATATAGATCNTTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGT
+
9)?7=!16)D;$E6H7@''2/F!.&34.=$G'H%@4?7&1H.FE*)@2-'>+#=0-=)638=AG2+EE8+E/-HHB0-F&6H9F)-A
@r480
GCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGNCCGT
+
(156"$$7-2F3::6.+-.4:<:=$>=,2;?>.9(.7&EA.B97,*A(#F#/G=
@r481
NNCNCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTNGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTA
+
#!#"+&$'&+$+"!"))&%*#!$$$'(($%$"(+'$#+#$#)$$(*&'%'()+""*"&!'!'()&(+))#"+#$**&(!+*$#*$"$$$#"#(&!''#$#
@r482
GCTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTA
+
GG88H3831<E9/%>:#";"%/B#84*;CC-6-E)#'+2$
@r483
AAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGC
+
H2(DG13-/:C63,C.1@D88=E5'/F1!0"2/-B!+@'!%/7*-!+=?;G
@r484
NTTCTGTGNTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGNGCCGGAAACGAAATTTGCATATACCCA
+
!'2;"%%D18D(-=G7GC&(G?=D5-.B6'(4!B)>&"</$BC59>&$H$*8#$)=F"#+82G!(@";,8=37C,@@FFFF"<91H9;:5*H18D+
@r485
TCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGGCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTNGATGGCGTTGGCGGCATAGNCGTTATTGCGTACCATATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAANAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGC
+
>;9BA&<>-59=05EA1G&A+C500!,&'1%/$-->.!$E4@237H)!BC!.".,$(7<;;/>E"+ABE6)$(+E$A<;2+$@'?D"$4B#0+=.+9/4;/7AG.B5):E7B>C47$++($5H&>E@?/9?$H:1&&$;!7..6'&2)5&"G92!8"=&(6-';(<=?A@B*+$//*/7'=0DE.=$F<)!H$"!*&:H;%6:"0;'=1?612DG,3,'1,'7<<&+H6>*6)8>H!!#).$.-2!.'A!E8A7/14B@@(&77+FF!>8:.#2;/=A2'5"E2C9G3)!F%B"!A3>"5041CD<5G"C:1.%>#>#/B=35'<'@2D>@%0<+%H-A2>A#+'?7212()EG$6-=H23.E"9*2F=+0%;8/$B8>6.+;4-?:
@r486
AAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCA
+
F5<B$F4DH3/'=481,3;.=?,;*2F9&-%H&;;$%A0$,',@16D*43CC/H"*GC2:7=&<::A2-F+5#=$+@G83*@-.?*,<?;8,E%96D(C*(E?'4!$25D".@:?,/"G"
@r487
CTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAA
+
E!('$;%CHA0$<64/8":HB++G+&?6:1%.+*B8,:5A$,70$:$HE*$9+
@r488
ATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCC
+
'+)&&*+%#&+'%!*%"$+%**'*&))(''"&*)*"&+%!$(&#!*
@r489
CAAAAATATCCGGGTTATTCGGGAAGTGAACGNCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTT
+
D6<@>#A>2B9">>6*=3B&!3#1765E?.B"//>C6=$+**1/B<,&C<H(@1H.#5?1/#!HF3*"6&3D<#+(G5+4!/&A2EC")&(D4
@r490
CAGAGCNTCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAANGGA
+
!67B=5FC.::0902#A.B4GHC2)5BEG<;6'>2-@(H)@F(&>7!;0>1%:4B##)97.5F%2#5@A>(&6++:-C/<F6E-1:&==-+%3&8B:),9F,
@r491
AATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATG
+
4(/3&<&=1.9!>9C8<"=7"-%57:;(00>:?5:8.#D?3).6H5?F2A0%'"
@r492
CAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTG
+
21?9F1=%+0>:BFB'6H((;@%0F9-%:,A?6*:7%"/&BCFF;)41%>=GC<BF=;2>@48-G0#3B)7,<C,<?@@4,=A<'=#/@2*#4C#6FFA,0,>9F$5,
@r493
GCGCGGTCTNCGCACCTATGGNTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATAAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGGCCANCGGCGATCCGGCGCGTGAGNTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCNTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCC
+
"(*(@G-(<$109'8"0%@B$B#;3'"%8C27(!%,),2)75!=B'615?+.+F&4.F+'@6*=1-2@D$9D=9:1A'3FC=+?3.7@A;/6&C(1,?/%;?A"G$110AB%;4$,"E<F3/6F+&%C&47D)<(14$-#H6-;+(G".E@>G,6?8)8%+!-C*2//F)E.*:-E14GF2=%8',:-*:>G!4*;7/EB>;2:#H;90*,1/*?.*',:H>0B;?):AE'
@r494
CNGGCAAAAAACTACCGNGAANAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACATTCCTGGGTGACAAGCGTNNTGAAGGCTCGGTCNGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGA
+
$*($+'(++!()'*+!$+#*&%*%*%*&$%$)"'"&""(!(#"++'$#!#(!&"(+$$+%)''!)&#!+%#)(+(")%!+($!*"""+!$$''$+$*&&!&(!)!")#$%)!**'$(#%$&%+$$"%*$#%(('+%'%%$%!)!)+%)!")*)#!!$!!$%%!)*)+%$#+!!&###)%')$#%*
@r495
GGACNCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGNCAAAA
+
1)A?E*;0:9BD",-A40@"-+%C24@!=<<4B'4*;E&;8D>E0E3-&?#;
@r496
TCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAGTACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCC
+
=$4%,5$/H"-.'*%EA<D22:+,+B&+35.,1B@=C#?A6"3#2B($+@30',3<,8CHGA>)F"@,5=4)@8;<>=%C&:G44>9BE<4)E+4*>-
@r497
TGGTCCCGGCACGTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACAT
+
=/A;3(B:8==$B7$5%"/@B!C631E8('H,&3!$(F5)A1:43&2H6>,+@+#AFGF
@r498
CTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATNTGCTGAACACACCAGTGTAAGGGATG
+
3-D>8/F@'8D**D*G;904B29?%%:2&%#03!#0$EE',(/($9>F89?8=C.+59>"7?E@(B9-5CG<>D-&>)2!@$>.='1*3G
@r499
AGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGT
+
6/AH12%/,"/*7(D00E4><?,H%?D1D*2@E=C:$"+0''F@/
@r500
AAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTCAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCT
+
.FG5+=0#@C1//G,'20G-B/GCH=DH?C';+/)$3/5#+C6*$"@&"A-=*(0$<C$,!!;13!B@:E#A"")1'!FAE68,@'6%(6B2/??%7DD@;<+5G8/$/"<"&
@r501
TGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTC
+
6#F:C%7+61;5)4/!E2+$G+&>2D2(<!/2%3!40>7-.94G!(&H--><:&3#7+(*BB6#G-8<9G.G7
@r502
AGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATC
+
>222.3%2F6<:CFH-!$B,B=)5C$H:@3'46$H:115E?B<E20>F2%A,6F,)B.>E26*5/H%7%<>DH?#6=)@A:7'3A20<-:3A&=%51?:7G.:%G8'183,H#4<%$1"
@r503
GNGCTGACACGNNCATCTTTGGTCATNCGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCG
+
)"&*!*')")#"#&%+%+#%$"*"!""(**''$'*#'&##"!#*+''&%"*%&+%&)$+!+&"+!)+""+&+$)$!))+&+$)"*"'$!"&!&
@r504
ATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGNGCTGAAAAAGAAACACCTGGAATGTAGTGGCGGAAAAGGAGATA
+
=0F+#".'()8H+8;BA-255$A$#%'A0;(,FF99*0$!=3>H30'&4&F.)8:+9'+(5$$9?,7(C,),,:@.&=1HF6&1$1-.0/1,4."
@r505
CTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCANGAAAATAATGGGTACTG
+
<6!2><EB***@$+F7#H<FC/BE(HC%:)EH79,/;C;?:/6&G8.6E7':;(,89CB>B,>CF+1,+
@r506
GCCTTCATTAAGGGCTGCGCACAAAACCAGAGATTGCTCTTCTGTANGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATNTTAATGCGTTTTCTTAGCTTAAATCGCTTATATNTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCG
+
&+)($)#%*(&+"$$!#&!&'++*%%*'#!('$*#"#++$*"*)(")%'$("!$!+"!"('#(&%&)"'&(&!!#"&&#*"'$!'#&'&$%"&&$"*'&'"&*+%*'*$"!!)'&!$!'!!#"($+*(#!%*"&+$)'$$&"*(!#)$++!'%$%'&(!&('
@r507
GTACACAACCGCCCAACTGCTGGCNGCAAATGAGCAGAAATTTAAGTTTGATCCGCTGTTTCTGCGTCNCTTTTTCCGTGTAGAGCTATCCCTT
+
2&=G3977%,+1=4;+<"3B2:9C4F4E>'6?<=B4B"=;<!"A@.&/H=>D(#CGF*#'>.8<1@4?/D61#F--**=4>>4,HBCH3H4&"7
@r508
CAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGNGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCNACNGGCTCCCCCTGTCGGTGCAGCGGCGTTTTC
+
7C296;A0#5;D+0D$"'5;'55,?!E(79?GD/4.0EC#.!4C4H"#8/-%&(4$E#"*(9GA#!@80"?4'EC6:<+0D70D7%79BDB1+'A;-+4+6G'3?F((6FA8/B64">&&?$;*B..00!D*"$9A>*/E+0FH2G?G*$H!FH"@=%2BG=9?257$/F%+47&A';61"/)!5,
@r509
GGTGGCACACAAAGCTTTGCACTGGATTGCGANGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAA
+
D?4G0F:(5->6%8$=D5-0C%7-BE.@%B;0<<0F8F*$6'>5--7,.A76:-1>DF;DF4$$%&A7596DD5.0A$'9,4%:;
@r510
ATTTCATTACTCACTTCCCCACTTGTTTGCAGAAAGAACAACAATATAGAATATTANGCTCG
+
&6.E"=4=2>.:)C;*7815/;H-;H3-2*!4/)8$(+8@+E7%7,,CF%'8G?'@)7A:,E
@r511
CTCATACGAGACACCCAGCCCGGCAGCGAAATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCNTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGNACTTTTGCGNCTCCCAGCCGGACCGGCGCTGCGGCGTA
+
A=<:@?0=:"5C*=3.'72!6);0)E*6/H2(A!DDD/$$=;@%E%:-E7A?<.,9;&?!79@##25%%-$C1)G9%-35,#@9C*#7;;HFG4GA"4*2&)-@3/);$.#71%07@5E8?206A>(>5851<%F#3)+E7HA<HE!?A".?*.;;9E6"2:
@r512
AAGAAGTTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGNCAATGAATCCTGTANATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAAAGGATGGANGAATGCCGGCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCAT
+
$'+(&***%$*'(%*)%)%+#&+%*+'!'&%(%(&%!'"$*+&*('!!%*(%+#+*&#"#+(++*&'+"&%#$&$*##"+&$!"%+!!)(%%!!#%+(!*#'"!%)*'+'#$)*%)%"$("('+!*+!!(')$##)+(*$)()"(*)*"()!+%(#)"##!$*($(&'&+'!'&'&&+&!!(#&##'"$!'&")'"(!("+*(*")#*"!(!#''(!'%&+%)"&'!"!#**$%'%'$&'"*)$&'+!#("!%'*&*
@r513
AGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTNGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGG
+
<"&&;D?H+1"G%"D4<:/HB7+0#;H)4?<*@A)'8CD"'-?3>!4AB&($!@>#E$B:E*(55'#*G#H+'5-2A2BBF88!63*#H,8@6;F#5+2D':+2&G4&27#(G($1@!6
@r514
GTTACANCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAANAAAACTTTTCCCCGATGGAATGGAAAG
+
FB>0=*@%2*55E1"?E?(@'$44=-!E%/7H=CC@0*67>+1H0;$3"#6')->?(A46:-@='.*93=-6DFC7AC(;+3F9
@r515
CNNNCATACAACCAATAAATGCNGAAATGAATTCNAAGCGGAGATCGCCTAGTGATTTTAAACTATGGCTGGCAGCATTCTNGAGTCC
+
''""&("(%+#('!%("%"(%'""#'**%)%'&')+&*%*))&(($*&'"!%)$'*)"(%(""$$(*+(#$"((!))+(''#+%'%(#
@r516
ACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCG
+
BDF*9!/2G&;E#@#D3H%$86:'H?>*83@HD$=&:!#!/,4E0C/&+;
@r517
CCANANGNCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGAATCCGGNTGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACC
+
*!(#&#*$+!"$+'#'"*+)""(!)')'(*))+)")!!%'"*($!&)()*'+'+'*+$"'%'$)")$('&"&'"$&&!%""!")'&"!(+"!((*$)$*)%(*#(#)*%$)""#'$&+
@r518
CAGACTNTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAANAGCATATTCTGC
+
=DB9#0F4!8EC.<9%>"5A;6<0,H,!H*H=8&H3E2#;$G5%5.$B%;.D()+$2:B@?'+%77:0EA"C8/"(4E)5%G,$-*:;66BB
@r519
GCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAA
+
"H<B9!("A(?&2B?./.?-H0D(!<8B616@C2'.#10E6&-0)&F,&@>9/!FC4!&'95AF0E1?)/D<E3=(:A.9&)<F';=&"9?=8"D#-1=7()?(;955(6'7"3"*@*="22/*7;HFC,#E4.:2"&==57:;+;A29-H6?@C)D
@r520
NGNAAANNAANGGAANATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCANAGCTNGCAACTAATTCAGCCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGGAAAA
+
)'"%(#$)$'"*+()!()&!%*+%(*#*&#+'+)*&(&#+*#%!$'('+"#+()''$#+$%'&%(!#+"!#$)!(*#&(+!+'!++$"&$*(%&+%)')"+(%)%$&!"*%"%*'#(#!#%*'+&&)$+#&!"+&#)(%+*"%"#!()&$$&($"
@r521
AGTGCCCGGATGGCTTCAGCCCCCGTTTGCACACGAAGGTGGATGCGGCGACCAAATCGTTGTAAATCCCC
+
;/(H8.=*'.7348-@)@(7-54)*E?C2>B9B.?,>F*H:@74&*(!C=;88@6:FA?'.1EBF<D;24)
@r522
GCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCATTTAAT
+
))#0/6;!'=9D,,-05$5GA1.3E>*8A.5&4>:0E(H@&%6!3<18>+@0'7"<
@r523
TAACTANGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGANGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCNNCGCCCCGGTGCTGACACG
+
38G)E>*?->?7,!;G4G<")$57/&:"<<:$$2D+@61:8>3919H9.8";#G6"E5"'E9</D1A3.5DDG147*/8+()7;&.?@<106!84=1:2'CC,HH"(9=C/*<'B.9=!@D0-*
@r524
TCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGNTCGCCAACAACATGCCGGAA
+
E&&D?=$9HGA38,/DF7!1>#@9)@2HF7GG.H@27?*D"G"#;-$83A$;>!+*0C6/HD:/'
@r525
TACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCGGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTATTAAACNCAGTAGCCTGGNTTTGTTCTATCAGT
+
@$F42H$80CE;";1=E@(#%3>&(23&?7<?'<$!?,4GA6>(0.-&8)'16C#4F31'H43C15&+A&5;+H#400$?,B4!<F."7%:@)1<2?88"%#7G'G</D@4&D@:;%DAH8H5B9:7*
@r526
ATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGA
+
(?5)'G'!F')*6@/?=/<;?(7?A?:$;1%G"2+<55#/=*&8%")11.#3<E=#-"9":%@(2-:&8+!H1:,C1
@r527
NTNAATNANNNTTTTTTATAAGCGTCGACGGCTTCACGAAANATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATNCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCANCCAGCAACAGGC
+
#$*&)*!&*#'*)''(++*$"'+$'#!&!!""#(*')+&#)+*"%''&$*&*!(!(%&'(''+!"$!(+'$!')'*!%%&!+!#%#+')*#$$+(!%"#!*&*#%!#$$''##&"!(%&%(("&%'"$&*$"%%%*'!)'&$($+"+**&!!&"&+&')$'*#'#)$"("$&"#%("$+#()#$%**)*+!$)&+)+!*$%(*&*#"*&%%$(*$"!!'$
@r528
GGTCANGATNTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCNGNACAGCCGGGCGATGT
+
&#!*)$$'"!"+)+#$$&&&*#($%$+!%)'")!)#*!)*()&*)(&!(&((###$*!**()("*("%'(!'#$$!*##$
@r529
CTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCT
+
+&3020C4>'&.-71.>#.30>0$B(G4AC=/&=<-'<;;&C;+!53*3)$?/"+"&!)<F@@@&G4+$2A;>9D/B6(-,H48.EG+&
@r530
GAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTNAGGAAAGCGGANGTTGCG
+
<1=0E'F$+,0%#C0GC7@G=&07!(2'..)E?7;2G8)B;4,G@B4,-17D#5B2:&:#AD5:05F##'2-1EB+%
@r531
GCNGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAAT
+
$@8=$;G5!B@.D98%B+FH#4>1+'":(!:%6*?0@"#/28?0*"*H(&;8=$2G9EB;,1!H'5/F=$>*(19%99?F@F-
@r532
ACAGTCCATGAATTTCTGAAAGAGTTACCCNTCTAAGTAATGAGGTG
+
E9!$0?:8#;,;)*0F;"/C#C9A/6;B%,G$>H:0:017;7>"(2(
@r533
TCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGAC
+
&/4*+B%@::G,&52,A;+D0<!4DG@4H#/-C@"030>B6<&6*"G?0303?<@@,#E(>>6AF9
@r534
CGCGNCCCTCCCGAAGTCAAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAA
+
&&*%$+"*##"%(&))'&'!#*#*')&+*&!+%+!'*+(%(*+!'+!'%"#%%+(**%)('
@r535
CCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTTTGAATTGTTTTATNCTGA
+
!%(+&$("'*)&+$()'!"#(%!)")'(*)!%$'*++!$+)("!#++'%)#(+$+&*&)(!($("'%&%'(&($+!+(*$%"%#!$'&#&)&)#*'%
@r536
NCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACCACGNCAGTGAGCGGCTGGTCAGCACGG
+
&?F0&>')59A5.FB4BH&0G,(@4;B?4?E@"/*#=.-<@!?=<?A/)=5+#@)/G'1@)2$3:?2!A37(:4)D2(&<"5
@r537
TTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACG
+
=5$,!2B*75<1?H%*:70#48A26($!F4<"/1D$6A><H:=",&17."F307.8"1F"#42,#BF5&($'E78<7@/;<;
@r538
AGTNCNNNNNNNNGCAGACCACCCNNNAATNCCTCNNAGCANGGNTCGCNNNN
+
"!!!#"!$#!"!!!$"##"$#$"#!!#$$"#$"$"#$###"#$#"""$""!!#
@r539
GGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATC
+
7@96F+(4,D9/AD0:&"36=/&(&G7G+>H3=9*E4)0$3B%G5-3!G/;'?'7$;E>";*F<;.14>:.:$72D>2DCCEGE+;D2?!G'?=GE+G/#C@C(+4--(DD&7+21-?+E
@r540
TCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAAT
+
;@%0!$9>-49=A*&>686!*<:EC=+/B>@FC3.>DF<5E/.+0>"?>;
@r541
TGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAG
+
3E4,CEH"<8!H??G,G5%!B2)<AG388'F!/9(<H4(7H$3"*7$.;?62G(2$;(2:&H7&=?8+GC2/&$D112;*/$EF72
@r542
CCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTNGCAGTTATGGTGATCAG
+
88G"'F7E>&(F.3%*5;179%49*!-":)/5*:C(A=BBC!1!;(9"+12*6BGB1.498=H@)*+5369*53D
@r543
TCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTG
+
'B87:(%#&(FG93F42GC%95>"9"@4+FC,46<4GA$C!1CC7E%!3B9+&=?@4D99
@r544
TATCCACAGTNAAAGGAACCAGCACACAGGGTATTGCGTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCN
+
&6"0G6C?A@:'##"FH.4A!&>5$>.88<D@B<A9$0>"C>17H<64';(9>)B.D'"BB5->68H3.E7,.14BB7..6)7C;12
@r545
GGACNCNGNGGANGNCNANNTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCNC
+
)(%)#$%($&##!*(*(*"))&)+%'(!'"#+''#(&)((+'$')""'+*!%((*!**'!#&+&%!'*)!&'!(&!&"'%+")!"'#%"+$'#*%'!%"+$+*#%')((&#$&#(#)%!*'")$')""))"%+()#%")&'#'&&'$"#)%+($+*
@r546
GACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAA
+
7')<A(-*HHC%+A%=0%CHE';:,@.D;="15:-F#)?C'>0:6&#->*.
@r547
AACTTCTCTGCGGGAGTGTCCGGGAATAATNAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGATACGGA
+
(+&&##()"!#%!!"(&"$#*+'!"&'(&'!)$#&&'$$$++)"#%++$+*&*&$!*)*'&#&*%('+!!+%&"+'!$$"&!+)$##*&$(""+&!*$#$
@r548
GGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCNGGCGTGCGCCAGAATCGCTGATTCTGTCTGT
+
*?"BEE580?D?BF,D;,!55G*;.,6B?C!4A$F6G#C"8E!6;57BE:F&D2+BH3E"'&00>"98<1.6<7?1%>B,A:?1G499F1?C3)%=B)
@r549
TAGTGAATTTATCATCGTCCNCTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGA
+
'(*+)&+&)*%)'%)$+&(&%'#$%#!!%$(+"%#"!)$*""#((!#&'***%''%"!*'!#*%)%&+"#+'()&&$!
@r550
CCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACTGGTATCCAGCTTCTCCTTGACGGTNTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGNACACGATGATATTCACCACACCGCTGGNNTTCAGCGCGTAGGCTTNGGTATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCC
+
58A;+>&>*<0<-+E8$,(27%65'.#G@B%B#)!:&=45+?E.%)$;H&'$@A8%70+)8A=7()7E4A#9H;4>+F'1=%,5!'9&0>7A:H9:<E1*69.&6,=$?7!?!<'G:<?@2E(6.D!+!,96-@B/=F?G:295E.C%6+E;75&>=%G(*))D3),C$9F0*>->B&-18!%-?%?>-+.0@);;#>-1@GE
@r551
NGTTTTTGCAAGCAATGCGCCGNTATAAGCATTTAATGCATTGATGCCATTAAATAAAG
+
#!**+$(+)(%!'&%$!"$(+'!%!'$!*#$#*'!#&'$%(##())$&""((&!"%'%+
@r552
ACTAATACCATCTAAGTAGTTGATTCATAGTGACTGNATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTNATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAAT
+
.CF3!<2:'(2!&,(%-/17=$!)21#?'>7(?5G9>'GH8EC"!*%;><H"6'G!,:0.-=%!CB;H%.";E=,%852GC0CA2"EGH040.*B8<H9-H@=/>+5!;*(*&6"@373$CA&*@H9-A75$3-AH2BD)=.EB7@2+>.;"8A#!!!E7+%=(,+6$&E8;&'-D31D8/3398&AC,+D;?6;(.*B9+(:!#=E(82%BA5,;&C)A0.<.1:?")%*G>
@r553
NNTTGNCGNCGTGGCAGAATTTTCTGCCGCCGTTGCNGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAC
+
!!('(*&$#("('+'(&+""&(%'*)&%!!!!+('"&*!'*#*!%!$'&!'+$"*"$**"&&&$*)%(%!!'!++)%")#(%#$%!")%)('$+#*#"+!))#"!(%(
@r554
GGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGC
+
7#!'"'GA0@3HA0:">96(,6%4+82>@H@!!&-%#0C?:-,6$8D*;1+
@r555
CGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAAC
+
.E)<+&"'CE4<=D@4D2DD0%*6!(8,#9D8-#B@G#,0$>!=11F,(C-!8/*F2'*G4F923#(1*;$@4D
@r556
CACCTGACCGCAGAAGTCNCTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAA
+
D%G*)H1H5:#<3.!!//6@45'B&87!C&;2C)%2;A+/0<E&@>*9)@69C.>3@7C1-5E=0-64CA+%</?.%(
@r557
ANTGAANTNGGNTANACGCTNGTTTTTNNACANTTAATNCTNTNNGNNNNNCNNNTNNCNTGNNNTNNNNTNGCTANNCGGNNAAANCNTNAANCNTNNNNCNNNNTCNTNNTCNCNNANNNNNNCNGGNTTTCNATNGCNNNNGCNNNNGNTNTTNNNCTCNACNNTNNANCAAGNNTTGNNGCGNGNGNNNCNCGNTNNTATCANANN
+
$!#$!"!#"##!"##$#""$!$$$$!#!"#"""$#"$#!$$"#!""$"$!"#"!!$#"#"!"!$!$!!"#$##$"##"#"#"!##!#$"$!!"$"###$!!$#!!"#!""""####!""$!!!!$!!"!"!$##!""!#$"$"$"#$!"$$#!!$"!$"$#"!!!#!#!#$"$$!$#!"$$"!""!"!!!"$!$$#$!$$!!"$""!#"#
@r558
CGCGTGCCTGTTCTTCGCGTCCGTGAGTCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTGTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTC
+
+B6'>C$5GC62$>A#-</)3;A+DDA7135HG?>*,4#2<DF=9;"-)D(G&0=#.>4B$8+)<&)&5EH"-H<7**8H2'8=#2HE:8>"*G7$;<D<FD%8#;/E013"5/':AD*."E%A7/A:/<.+H+>;>131=C*<#*"<<+)
@r559
GTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCNTTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAANATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGNCNTACTGGANGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCNGGCAGGCGGAGCTGCATAT
+
1GH5=C55E6?*42(:5DC)92H+H2&*;G$-1A'==0)34@'HF7=HA!&&,F*:.'D.2*$9D@(#(G9=8"E3))C2/2$!(!:?#7<:E15&=-<&"D60F?=*=4?.1-BD?&C.B4G.@CD?:H-:<0>+4!H+">F(<!@#42($%5+<:.8;320*;2(-D9&F<8$)=;/FE01$3--,:CH,9@85C*F@+?4C+B#"@B-8HH)!>(<+C3G36@,.,5H4.C?>8.4-'!F>5/'7338"<2,GB;12+.<?D4*F#89*=%@/HG$A()"H?./$A183$D"21F-/E)81';,C6!#(G=23,)G>#%A#.?<3*?FCD+),5+CE*?!C>'0A<E,6.7<?/'FA;@'"
@r560
AANNNATNAATTTACGCCTTNCCTGATAAGCATAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACGGAATGGATGGATGAATGNCGCCGCGAACCATTCAAAACTCGCGAAGGGAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCAGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCANTNTCGAAAATACTNCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCNCCCTGGATAAAACATGGAATGACGACTAATTGCCG
+
*'$!)*%!+!%(##*%+$&&!#$()(!)*$$'++(#'!$+#"%$"#*#'++*(&&%!&'#)*)')!(*"!*#"(&#)&'&"##%&"($(&!&$#'&*)+'+#('(!*&*)#$&!*(%*+*)#++'*+(&##"&)"(%&%""$)&)))###!&'$+#%!&#*!$*!%'')%*(+#!'+'"#*#&*%)+#%*'&&)*(%")**#!**&"&*)))'%+('")*&#$)$('#)"")*$(%"&+&$++)*#*"%%%"))&$)(*%#''$+%++'*+!#'&)&$#"&%+%"""")!+$)*'#)!#$)%$%"*$!(!*)&&")!%*(*%+#((%&*%%+)+!(&#+&#%%#'$'(&'"$(")&)#&$(+$!""#(%'"'"'%#&"+(+!!%&#+$)"!&*%'+"+)%%!(+'%&&#')("'&+'+"%$+(%(#+("+""*&%&'(%*(#+%""$))%'&&%&$("&!'"%#*"'%+")#%*++$(*#'%(+)()&*
@r561
GTTANGNNCAACTNGNTCGGTNNTCAGGAACATCGCTGACTCTCAGGATTAACTGGCGGTGACGGTAATTTC
+
#%))&*#)#'(*)$"!(!%%'$+'#(('!!%""'$!#!&"##)+#+*+!!+()(%('!%+)%'++*$!#"#)
@r562
CNANNAANTCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGA
+
"#)"%))!$+#+"%&'+('('&"'!*!*'"&"#%(&%#!$$%&#))%#$"'!)*#!'++$*%")+%
@r563
GCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCNCATCTGG
+
B&;;1:;H/->>($H4>=94,%H'56'H@;+D#/?3)!)%H&:93&!C/%5=:$7-#9.5$--86
@r564
CAAGTANAGATTCGGAAGGGCAGCNAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCNTATTTATAC
+
)56"C+01<--,;<2%.85HC4B.8?-.$E%;?!C2+$"3?#4.1;%EF-65A54E$0H>E#F%B5'GHBBG$":EB,
@r565
ATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGT
+
<%1'B3D;G5(&"-5<*!:15-7#>9'2/37B4@4'/H)@&DG8<G-1963%%F2+,,?'>+%>78$D.6)*9-E4.E!C?GG6?2-<&&5=-.D#51*AEH+%3'/:CA"+A$/D/!B7.%64(+(2754#/7&/-C6$A,E((H2<=>4386A<#CB7AH-)"4&E;50#7C+C/56.#"*
@r566
GTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAA
+
F+C&?A)!8A72*A$4A3,.-$(!$'1>!33A4:)$("6,<"F/$HB'D@D=E(:5);.5895:)':);1.>'.:D,,+F=1H,@
@r567
TCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTCTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCNGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGNCAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTG
+
H;H15-<*H"?!$'7'0-+FF5(!@$;@AD66D4'8?17;(E2>,$2G2#$>*C-G8*)0@C=&A4%B$,@F!+*F#);'$1E8AG3B'.2*1@?$;8F6H.+?4F,>G)=7(;66><*<"<8C.39'13%.:@$/+3%C%@B4FH.#C1-;()C6(9/%0!"@C.F(E8'))=')A'8-#H3(E&42E+8CAE0E>%H(@<3A2#<CD9(+73EC97F#6.,.1?&069;F9*C2GAH60'C
@r568
CCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAANAGGGAATAATA
+
H8A'%4*-3(#+93(4)3F.'=""(D3/;HE&6"<HFE3*$0'@=1'&C!%?4")+G%/F:-9GG+G!06>;G;6->8<9
@r569
TGATGGTCCCGGCGTGCGATGGTGGAAANCCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCNCGGC
+
:DG=9>+'B=<8?'8E%-&=&@C+A=-%0G'9@<?3:G90G+:?D>"7DF3$7$/BFE>"%4**F*&*?B7%.8D%BE:+FB;5A;B-?G9
@r570
GCATGTGCTGGAAGNTCACGTGTGTGAGCACTGCTGCGCAGAACTGNTGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTANAAACGATGAATGCC
+
%';HG6E20-@$5-'.C3?,*>H6E1>&6C!C$#F7/(*AB*C4CD4>)F3:.)!H2(F<(!97,-C--3.%%</5D;E:,F1*0:>$/+;*45;0*7B$.D<(@:@6A>D'3A0)+B3GE!,@6A.0!
@r571
GACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGG
+
7H8--5002:H*$03&/#$=D;+)/"'<)'B+8B%-(8.21E6::0#D!
@r572
GATACCAGCTTCACGCTGGCGTGGATCCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGT
+
'8CC1!321(E76G(7"'.6>D%),0F$#9#'<$<)0H/#*'15()==*,00C+1.D-F:1
@r573
CGGAAAATCCGCCTCATCAAAAANAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTT
+
%3;4(<+$E&$H(3AD7F3172,:;D83+,!$42%F&D>6'8AE*FD=-?E<FC)369(H)H7+?G
@r574
TGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATAT
+
4E*""C.#'0>'141G(*A"0;9?4B$28'>B35A&&-BB00.(5H
@r575
TGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTC
+
=<B347EB01/?B!?9+9;3?1"+(;),;)<2#3:H6+&3#11CG@:7%;:'1B03E354(:/?/5.<5H=1$
@r576
CATCAGTTNAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCA
+
/';<)C1/E+;!4C/<.4D2?:(+EH-5A)8G5@)0*'1GG#80C1D3+*!;94:.A/71<)$*(45CA77
@r577
GCTTTTTTGCCTCTGTCGTNTCCTTTCTCTGTTTTTGTCCGTNNAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGTCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGG
+
+)%+!$&*%(!*#"%'&#$+)!+)'+**#$'+!"&%&+#)')$+#!+$'*(*)%%+"")'!'$#"*'!'(%!#"+#$*'''!+"%$$**'*($&!'$'"*%!%"+!+$*)&"+#!$$)"$'+%%)&!*#!&**!#%"$!&(#+%&#'**)#(#)!""(
@r578
AACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGAC
+
)C5F,7*..,%DF9+'G+88*%=<3F?=60:';G%>F#H6.<G1-GB94.*D4H,F%BF:4E-)/=.G1=''<-50(=4@$E6',*(=HCH(G33!8#8,=#"#"76!G7--?EG30,-;C):$B5*!1<3>66?(@
@r579
CCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGT
+
*96&/?7(+;13=5-+"+0:7*H2='>.?C++,A(5=@A>7&23"E-$D3>A=38-&#>/B+4'*)/B#,A):@F%0GH8<4#8.+
@r580
TTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCA
+
96$(A!(4+*$?C)G2,5*AC&,H?34F&(.<+!<<,G*G5;0-C;#:.1<%G=$;:<=A%>#67(BBE6/,6<C=$=/
@r581
CAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCG
+
0@"4?95!.:%*F7H89C!9BAB;BH884)&!")4@3+:-G-&:1?70;1
@r582
TGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCNTAATGGCGGTGGCTGGTTCTTTAATCNCGATTACGACAAAGAAATTCTGGCTAAAGCNCTTGCCCATAAANCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAANATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGNTCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCAATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATGTCATTCGNCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTTTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGNAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAG
+
'!1!<%;FB2H%4<'$4(5D3)"5;&9=A"1+2E"7?&#78!D5+.;81A4F;4C"&=;-$(20BH+G630&+(8'9"517FC+@0,HH>(5;=24@*%?3"DG#:,.AB2)0@';>8.5##&=D3%D:4G4=7"D@E@7*59'B<-'G>4(<--@(0,4H!G-%HC;:'>%+03(G*(%!3%>2D)"9$#%+19:.?&H:13A"@F6B+:.ECE/@=8:11<91;6"AG<4#FC%4C66GEEH+7A.G1&>*030>7.(?*5H21@*,B=!?:-<D1D393-=0*,@B)?'!5"$0&5H'>'>!2=&4:>7>4%8;:+>@#G9%8.D-=B5?931#9GG5>C>-AG..$#,2AG2B4+D<$#7,F8FE$+/0<4E,E7)6?&7;"+-+<9*+(>D7FA#2/27@E5$-&H+HHE2%9:70"1%!5($=?0.&9$.)B??=<6<$9>=A<'&D>C/<5D34;;2%=C3=@/#+0F2'D;E"A/><B;-4&:6#'"D>/.AA=7*+E0:.%,;*.5&>>HD%@176!/H+(&=@03@)E?'4#'D-#&945>DD:-0D+H)0@@GC!4:#5@-:E-#?$?82F4514F<;'3#<?7DG=11E8..:!7A'H>194?#*=C0"%BBBG*(1*0:'7A(,);/?-()$DFHHC;3?-4.D0>FF65=1"/'6%))%#2)/B0G<2#C-<>2-7C"A=)(;;493?>D!A(<:+62.+4E!7E,&+>)09/>#).DH%,?4<&;-8F$AFBG.('=8!*,7F%-,91B5,%"DFA/#5(CHH;%,5=#$D4C>#6$2*GH2/&=,41E*&$D"(14=5E*AC%5?&C4(-?'/H*A?"A
@r583
TTGCAANCGGAGGATTTACGGGAACCGGCGCCAAATATGAGCCAGCGGGGATTGTTTACCNTGGTGAGTT
+
20!'C2>&.@+*,B8%E5+5#FA>.!0*56$319-&9'#B<,*%+!1(*3*"'66)1=4(H9G/(B60>)
@r584
CTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCNAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGC
+
3>,*0&3F@+;;.D*2/.C0(</HG"<=<AFD?BB<>1"?HH-$B<63,#-4=5%5#?45"8?#:>C:(0(D2E'34:)*F/D+-*;=@3042791B:#%')6%!30H388E/B/'$,H&>H-5$0+6-499B?H+7,1??27+1
@r585
GACCATATTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCC
+
;5AECC7,E?C?=%)/:A6(%C6+C,?)@'&9>57+.5"(.>D73C%&'/%A!&31#%*-8F3'/A7;:4::9
@r586
CGGTTACCCACCACAAGCACGCTGCCGCNAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTNCCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGNCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTNGCTGATACGGCTGAGGTTTTCAAC
+
(A>0&3?.*!%?A(*'BG2<>B&#3CH0A);=G=F.'<#G@2+8C<&:BD*2!B<:#D#8&A?&5G.D-F!;24):,/=A5&8:=!9C)B>1+H#,=/#9E?2''#3G2:F(C(;02E&H443#.HA?:F8'&G+8E(E6'5?:4./2#;BG8H#18&!26*04%=F-DB+'+:1-,)'HAC"(+B!7?:$?=D'76"68G-:C,/?!.B#<'-!DD7&")??G*:/89**"E'*<%8!<C1A>)G=GE(<;&<F63;91.G7;C9)1?20;)<0+F,=,D8B=)E.752&;-E!?*780%=->#!A>@.92+12&,'#72@(GG+6
@r587
ANATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCNATTATCGCCTGGTGCATTCGT
+
)!";;')$&#$8.B*DA*A=%E1)65FH&B75@68G(4.$H.3F49"44/GG#&B<,.3C-<>':A8#7<=#:
@r588
TTTNAGCTCTGCCACACGGCGCGCCNGTTCTTCTTNCGTCCCCGTCAGACTGACATCACGGTTNAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATTGCCCCGAAGGGCCATGATTA
+
+G)<GBA&12"B9D1A>#G<C!71&='&5(2F+#9.G+5.(8'&;74*D=05.2417FE2.C!.1=:(C(A<4'8>%<B1*0%;&D5+-#'$@D=D9G5>F"9;($:3+,.3+$0BF8582+";1G6E%1@5!G+13C8#915"3GH"E64!=?#&/*
@r589
AAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTC
+
9).+0<")$3$H50=5?D:&'$&35>>)&-,<)<7<D",<F/H3;2?*H@#4#D?D+$>#;B0(1G&-=1050G<$@9'>?!7B/BA1.8'/4-3=68;?48;6
@r590
ATCAAGCAAAAGCATTCACTAACGCCCTTTCCTGTTTTCCTAATCNGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTNCATNNAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGNAGAACACATCCGGTACATGGTNGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCT
+
?H4##;:=.6%.1!($*'$?*)#%1:A=D*-00A1'#*(;A@'2=$(C'7-61/F)85-E8AE5C4(1!H5<=13)C(4-3**7?#7,<!!:9393>>12G88?AG;/.9/>A"8-&48%9G#9(&&"AD)"0.E-A=C*95861.#F:B1.0B':E4!H/.9-!(4/:E80*=E+9!FB-(D?E<<&A+5=7*-7!;FC=#//6(*-!>&0!-=A)$0.*!B=@58&,96;4$0*-C0,.C!=-<:'G)<,)C(("A2$-<9C@-!22=D>$?+;1)9@-)B9=4>F%#(=&6?7:%%+74#:G5E@%5>@*)-H2,5;$D(&<G,!BB-?.9*-C+,>G:FB%H/.,35518C32>:4"H,+$;+GDED0&*:5?+>"7@0D0HH'(#%%5D=(F+#CA,51A<&">00/FF/@-B*H7,-:5:,9(*<F4E'C(&CG&!:.>/")B'$%,A$,(.6$4-(!B#&DB:4.5C#<2($$$%D?',&
@r591
ACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCANCGTCGTGGCGGCCCATAATAATGAGCCGGTC
+
A@5,40:>&=&@@=,G/?<11H$)EF1?;5/)9<!;<8"@C4A*F+8"CF"AA8A4)47G*AGH@9B/,%/=5*6)7#(BD>'<+*7<$C8:E<*-?=.B'E:
@r592
TAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGCGGATGTGGCGG
+
<6*E%<,6(7'(BB8B(7B%,A5=C;!&9*>1?'@')/G1CA=2/F<HA6.B5A$"$(&BA*A:47.G.@1C#?
@r593
CGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGAGAGT
+
>F;822,.1'-2"HD#5C0!&>(='B?5$6:7B1'A.#.,CH>0+)/3)@+5G3?)&73!?-C8-B;B!61G'&213$A@<,C(4
@r594
AGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTT
+
FGC0C8H-F$HC-2H048!6(!3@8C7=)G10A45$5H&7E&DA<@,.";>81%</$>-0'=#9:H21:4/#D!&%:+%@%A.!!&36&2@#G*"9.C$E1*6+(H%2,-23<$F1@H!((6@4#E791=/>9B,??4A1
@r595
GCCGAACAANGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTNA
+
-">=*F1)C*@(6.1#%;"918:(/H.=67'3.:6$$B=G;'E<=($4C&D6BC8=9/:8,%":(A:-?2F.A(1FA<7
@r596
ANTGCGNNAANTNCTTTTGTGGTGATGTCTTCAAGTGGGGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCCTGAATGTAACGNAACGGAATTA
+
#$*((%"!$'#("%+('%$*%+%!*%'"%'$&&+$)'(&!##$+""*""+(%)##(!%'"*(&($(%&#)*"(+!!&#!))*#%$'#+(")!#'*)!&'!"&('!+%(%++&'!'%%(#'#&+"#&*'+(%!$+#(&*)(*$#+*!#!*!*!+(%#'"""*(#!(&"!
@r597
ATGGACACTGAGGGGAATACCAACATANCCGGTGTCANGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCNGCCGGAGGNATTTGAATCCTC
+
(<1(&):(?(/$&D353.>FA,?ED#3:&9,17CH%3=:&;/"$)+7*)"@?3';-FD:#;9>4;-HC&G;4?CG/F17.H;;0G(0)?@)5C9'
@r598
TATCTGCTTCGAATGAGCTCAGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGACGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTNGTACTGCAAGAGGTTCC
+
'-H6C/)+(H';C/11G.(0,0?=B7,9#,8(3&%*.-&%E)=@6>/.#;1?/)*'*&B:/A'%E,$<;7<+@(A$*!'&6<?:=@*)E3("C8AB4G0#E9"#@;96?&6,@9*C3+3?E(:#0<.5H?G9!10180C$0HF'D@7CF?%'8$GBC3'<-H2-3+3E<5-:(902<(!+)5:A1.+:7;"1E/593(&@5E27;.%<+;5+6?*AC@,C<3A6
@r599
CCTAGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGTCCATTCAACGGCGGTCTGTGGCTCCAGCCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATG
+
&"!"!++")*$*$#+*"#"!$'!!'""&)&+)'*%+'+*%(#&$#*%&+&($#%%&*+*+(&#"'+#"&)!$*#$!'&)"+##%#*)#$'"*'*#("$%!)+("*%!+&$%+#"')#("#*$)+*$+#*#')")''+"+&$(!*')'"!'*((&''"'(%('"*+#!*!'&"%#)'!"($(!("(*!%!$+#('*'!"!$
@r600
GGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGNCGCTGGTAATGGTGGGGGCCGTCA
+
="G+0$<B;*AED'6=23'$<-2%6H?H%3=%49/C-3++/%?A2G"2@+A/05<9-17B$&<@BGF#A$G"/F(AH6)C/F(5.953!H$=D%)D".:+)H/.0"+@E9@3>
@r601
GCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTAT
+
@$)H=&FD5F96+$(8D-!',4,3&AC6<)D!?@69"!4CE.D11#@G>:1?*#./0BD0"1?#
@r602
CGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGNTTCCCGAAGGCTTCAGCGACCATGTACACCTCCACGCCGGATGCAGAGGAGAAACGCGCNACACTCTGGCTGATGGACGCAATCTGA
+
#?HF)045+>2A67F!4'6@,A(A3:H<+,0(2<-,A7>E%'@A-/=<1=3;/9+C#9"$+#?.$E2,78H"$3BF0$%,2C>.D2#H9%6'>/%B'($,?=A=,<%$H:&A7*/@*=024H749".7E$<>
@r603
TTGCATTTTGCAGACCTCTCTGCCTNCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAA
+
5GF;E3G>*;@(EB7,F<=+'G1-:!$?2H*$7E7;%1%!!%F$8D0$'@C-)+"B3;7'08'<600>EE)<#?-5&>3)BA+19E;*6A69++3"'2#C<#2=)B.,2'6CF826;4:B;@'
@r604
GTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTT
+
*2680DE*;>:&1&)6E?,#*DD"(3AD77FEE.?)FA%(&+1FA+-03
@r605
TAANTTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCAGGGGCTGATTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAACAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCAC
+
774=(:3=0B(3:)?=*#21+"A36'@++(A?(,,B/=0#3,CH'*7A@$<*B3DC&G@?'GD!3E/F,D5;:#,9D/!)=86>F(E-;6B2;F4!6@>=<8A&)9H4%-$/-C005)-!>2.&5+@#A33#(DCF1)4%?F?=A>2;E1:&.+*;8@/85B7CD.?,A424?&:E><AH+B.$C53F?A6(A;GFA8;-G#@*9E%4,>)3)EE9->C9!H.-D39#HBHE1!///A-"==@?/?
@r606
CATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGNTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACC
+
<$-8)%%"+9=@3!=(.2/1G@*0-0AFF8G%A/A!:?>$@9AH@"3<G%5"BD?'.'!/6<2+&*1)9=$,<$39=+!-2"C;@',%BD)HGB*("1!251'H"E><0A2&FE'3<#,*#G:#F4&?)3!1:<3:?*0G.-!C4)2(&A(=?HFC>?B(1.#G8C9C0@<C'G&7G?@A*%<::?"6/?(1)(D;1/*<"A,(@-3>DC7!"7%H7HC?78=!6E"15+&5)9#+F<209/3%*,B89&
@r607
NGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGA
+
"C7B>/A&?,!6F)'66%<.B2..110,942"H/11$$HG32<E$5?4+%A(</(1F$<B/E39707?5=1,*C-4>(86++!
@r608
GGTTTCACTTGAAAATAGCCCACCGTAAACGTCCCATGTCCACCTTCCGCACGGGC
+
:>?E581!(@+)C16&*,64*31)!&D6=6?8;/:!C')H3?)'*AD8/2(E4;2'
@r609
TANATGCCGTCTGGCGAAGAGTGGTGATCAGTCNCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTN
+
'&&+*"$$!*))$#!)#""#!#%+*%%*!!")#'(&$)&)+%$#%'*"*(+$*))!+"('##)#('!*%&!(*!&()(#$!')++&)*(
@r610
ACGGTCGGTCCTGNACGNACGTCAGCGTCTGCCCGTTCCATACCGTCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACANGTG
+
?CB8/E=46-CF&7$BE6:46"$+C5:-'@/"==#0C'0(DC1".8.@<(6B!4B%/7.B'0G//9-9G7*?AA-'#<6?+C"H8%CBD&<=%#8@&H6?2<95B?"9<8AB;<&27#2G%;=%H
@r611
TNNCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTANTGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACGAGAGCGGAGATAATCGCGGTGACTCTGCTCATAC
+
'%"%5;%F8A,*2"67B%=C">/$:;#H;;%0<8#3%5#>D7?A.;=4E/A.%0%DD3;%4G:!=DE%9-)",&$F<?;4C+/1//B-.DCE?7@:+,*D&'@+<0*E876'A-E8/;1#GB&;%A?:;D
@r612
NACAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATT
+
#*#'+&#+%$'%+&&+''!%'#)$)(+&&*")('"()(!)+#*!$$(#(%#'%%()+($%!"(&&
@r613
TGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAAT
+
6E=!7F5A"5C6%879<22E*H#$.F9(%A8=*D($%+>H3B/E$/(>@%<=C@1,,:C,@+2@H$$3/G6>7(-C46H'50A4,/")'!B'G;HE0/G3#,.5F0(>-=BC95EF+DA>AA%B@'2<E>A0H6&@1H<?F$!"!0$0)-;7
@r614
TTTCAGGTNAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCNTTCCGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCANGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTT
+
1#'!(3A8?-%=AB+/3!7G'2:>.;A4'0#=8%8@E4<>1H*E>*.%/5A/5=!BE"35.8GH7#(9;17E228.F@A-?@7HG"$,F6&E45*7)851/&>47C#EH&;$*(:#(4&;$'BA//1AD(9!8=G+7$E#7&"$4?59)+4C9FH%9A6'9,1)-G0,G*:>*/&D2>99?'...%
@r615
CNGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTGCTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGA
+
'%&+!"%'!%)!!&++"$(")!'!+*")%&"")"$*!)*)"&%"+''%"''!()!$$*&!#!'*$$!#!%$($&(%(*')#)+&(*&+&!'+*'*($#'%+)&*"*'''#
@r616
CTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAAC
+
,D8'??C,2C,BEE<'862;=A&2%BD=BE6F&.0E1+6/";*F8&F.0$7E096.41$)8.24"&C%
@r617
CTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTNTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGAT
+
:9'A-;F7-4@G:=/1180GA&"$(AF/+;C*!8$.HE$@HG#4C4),>79;@',#@/H6GGF=H5C8#-0.<BD"1BC)&;?%.$*&#8-!F74/9'7A')4FA(.D,(639761AE=*'C!>@7H=,"<.G-@<?)27)57"B(-A
@r618
CACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCAT
+
&.;$#H7/?5C=G31&0BF4A9=95.$@9G9FE.44E?=;&,7,?<,0,3.3%$B/)%@@/#,+6F-$%3
@r619
CCGGTNGGCGGACCTGGCAANNAACTGANNTNCTNTGCNATACGTGTCGTTGGCAAGCGCCCATACCGGTTTTA
+
()%*!*)(&)$"*&*")$%&#!*$%)$''(%"*)"('')!$#$$++)$!&')*+%(%)''#'**(""$%%")!%
@r620
GANNGCTNGGANGTTCCATAACGTGTCGGCNGAGCANATTGCGTATGTTGCTCAGTTGCAGCG
+
)%"#*&"#*"$#+%%#'!$*'(#!)##$'+#*&)($*!'()""#%)#'*(#"(#"$$!)**$)
@r621
CTGTGCTGTTTTGGTTCATCAGTGCCGNATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGG
+
B:G51C%,5EH6A),?;<'.GC)7@241A&56-34%4;>%!D4*3'8"E.."D,1(F:#&*>$8$5@$%A"E+5$<14,<E%<E3$-2A=)>'4+C/-;8%G
@r622
ACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGANAATGCCGTNGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGC
+
+"#&'&&)%&(+*!"()"&%&%#)&()+(()')$"$*&"))$+!$'$#!(&(##!+'))"##((!#("&+++(%*"#%+')(!**)*)%&)$%+$(%"!
@r623
CGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACG
+
:9;39CGE+3#1('?<"*9'(!8FD(4-,<!4/64AB"4:<<:>8.GD0989,F30@)3)G%%7175+%B0C;"?F-:12$->?8.;#:G@%;:23>?5F%".8$7'9&G51B47,82C
@r624
TCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCTGCAGCGTAACTATTACTAATGAATTCAG
+
?4..)7'&)00-//:=FDFA<6E79+$'6)G/.?H%"/0A*&%E#/27#@#17*$-1"C#65;.&$'=
@r625
TCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGTGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGA
+
<.9@7$3**E14&=%E#F?%*&(BH9?%!!+"H(>9)%4:+4946B-3*@E=H;44/E0-H-2?/5?-<1=D!$!?#A89%1#:006#
@r626
ATCATGCTGGCGCAACATGCTCTNCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTA
+
%=)%0A+#2A:DH"DA>.&.=,238<#B*9:E42D351>9H)7ADD?)/!#B5D-/?9H08FED1-$='F(@75$142F.,*$%$,;3:.B!C;>)-!7*2;=>>;E'*;)-.#'AF?,-,$)<
@r627
NATTCTGGCCAGGCCGCGCTCTGTCATNTCGGCTGCCACACNGGCAGAGACACGAAACGCCGTTCCCGG
+
'26%H#:-%."/9A@2$&!?)8$6$@.D6!#=(.6&AE!B>7?-!-$<"&25+@+.<':C0,5*-5:,+
@r628
CTGGTNNANGTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATNATAAAAAATTA
+
&(!!(!&(!+)#)))'++(+")$%*!'"($&%#%($%*"'&*$'")+#&++%'(+))!'#&!%(*&
@r629
CCCNTGNAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACCGAATCCNCGATCATCTNTCGCGACGAAAG
+
(*#"#*%+)$+%!$*'+($!&*''%#+%"*"%*$*+%$#!(#%"#"%%(*"(%)%(&&%*)%('')$#''%*(&*#!''!(')$'+')'#'(#*%(#
@r630
NGNGCNANNAANNNNNNNGTTNTANNCNNNGNNNAGCTNATANGAGNACGGNAAGTANNNTCNNNGNNTTANGGNNNNGCGNACTGCNCN
+
##!#$!$!#$"!"#"$!#$$"$"$!#""#!$!!!##$$!"#$!""!#$!"$"$$""$!!"#"#!!#"!"$$""$""$#""!"#$$!$""#
@r631
GGAGATCTGCCTNGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCANCTTTTCGTTCTC
+
#'G82H=-.,("C.2,-D,#50(-/''=;$"3GEH%GE3+';-#@B8B%5B@7&2/6*1:<
@r632
ACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCANACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGT
+
9,0*GF/>H58!'?.@35&DG!C'6"1B)(.H#"/%68"0#E2*28=&@4"#%%!?2*,'AF+=:6"!*D/$;+!#=),4$<&/C242,-92',#?4#9,5>,7$('0+@D7D8?.2:5%C<'##H>+<153?$12FF.1D"F8B9C5&8?*'@(3A3#@GC*++8+*'((E"-18'*)%??H=.@-1#:8"&&>0;@%%>>"F')>6E
@r633
GTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATC
+
D&-?&@+<<?=>+*?C@3#-7@B=9'%$D&717"'H='C#2!!6(;88&%
@r634
GATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTG
+
&0F&<A*2HB*%'8,H"9"E80(AA00+4-FEH<"@/1@B$7?$E$;-(2&7/+C/:04;BEH-DB?$+E+&1D%5-H3,*E:HC<*:
@r635
CTATTTAATTAGGAATAAGGTCGATTACTGANAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGC
+
,,1G>4#.)<!04#:5'+##AF>&9215-F<>#'5$80H+49&.>/#=?;=12B/6;C*>.@A8EG>5E-!A+%"%>3F+H"(328*!B-7("
@r636
NTTTCGATTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATG
+
!!0EH@$!%D8')81*-1)H*&9-)7;#'2>4E@$5-"!"136%$'"
@r637
TCTCTCACAAATTCCGGGACTGGTAAACATGGCGCCGTACGTTTCGCC
+
%*(*+$!+*'*'+%%!"%*+!'##!'#"#""*"$%%!")))!*$&('+
@r638
CGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATNCTGCCATTGCCCGCGC
+
7'/!768CA5*G@"//C)@E$'(=#B'!1##:348@#7D<"3A:D'(2+4(1%*(HG9,$&.;F,8&:"H3)+>EE0G!(3+*!=:,C1A'2?150.,5?;B8G0<.3<&%852%A?!*A
@r639
GCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTANTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAANACCG
+
2!2(1HHB49%F1?2@9F$-FF.20'?.F)++@F:'GB<%/3H"@;$4DA?!'*(+%-8CH&!H%3?*23F(8!D2:,'$H-=';%<$0"/*/443EH*11E!
@r640
NATTTGGCGATATATTAAAGTTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAA
+
!@(!D#E"G5'0A.D&-+H.7.=*B/@5?5/@9=6",)4(**B+H*?,)%+GA8E6F(5?=+<E/8C-?;!&851#3EG6;H00+'
@r641
AATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGT
+
!-*7G/3=H,*%<4"5@?70-7:F(.(G2"@@)9A7F!;$2?1-B&H<74>G<%?H:/>
@r642
GTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTNTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAANAAGCATC
+
A)2E7B"D;#!B4907/-@A"21E#%'5$9*=*#!/62D>"38#@&4"6=:#)!F8523-')<4%1:;3;57;AB-?1!&4<F;.3.?//<9:<7#3E1A,CB6,F$9&CF$#!B,G!::B))AE/,00-DE=-0"+:?!CEG'DC'."8.=$2,76##,9
@r643
GGCAGATGCGAGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCNGTTGTTNAGGAATATGGTGCAGCAGCTCGCCGTCG
+
D)&'#0'=2;:>32+@/2D-+CCG%.?/7@$$*4,9*/+%B(FGB5#)9&-:;2"AEF"/F@03//>,@E15;*8"!B;6C:9#01F,3=('F!E'8>F1?B72,2D74.C.#4F6%<
@r644
GCTGGTCCTTTCCGGCAATGAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCC
+
<,'?->&0C%@'.11C#'A,*CB7//:?(E7&/"<90GDFE;56.E(1/!5@8?2658
@r645
CAATCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGAT
+
9%$&!#6".B*8(:9*>)AD.<@6>!4+=*@8>/,).>;<>'!AGB"DAA:.HED6!%.4C"'7.(A9",;5()!'",;(!%.4(8"--0&+<8!#)C0(1#<BG?2#?B64F;0D;B6@D0;E)::,7:<2(=EC-%01#=-%/A7;6(4+C./@.:A1!3"641A$("*/+%+&,C,-5G3+-A('+-*.$"*
@r646
CGACTCGTGATTTCGGTGTGCGATTCAGCGAGAGAATAGGGCGGTTAAC
+
%3E?)$9@.%C=1>-B#,3/(6H*5=@B$*:;.8#,2C,.@/'CA17(4
@r647
ACCGGTTTTATGTCACGCACACGGGCGATGATGTCANCGCAGTCAAANGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTNCACCATCGGATCGCTGGCAGCCTGTTGCANACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTG
+
,87D7,1D=#@#$1(8:0%#19B?28++$:%3'A3,A0&(DB9"4&<$:"HG0.85G!1FGF:%0&-(.E0=H.9G>/8F>&!A;./;"'#&6"@=)495'H12/#0D>((-&:F?>(D<5?3:*@?FE?.("A%$?3"/43G',H<+</*:0(48@,H/2$*,.#B2"!H/9-.)58E67-$4!%!39B06G3<:/9::#14&4!.8E!D=3@H&8F@?G588389>HA-1>0(,<(>%2/D1!"
@r648
CGTCTCTTCAGGCCACTGACTTGCGATNACTTTCCCCACAACGNAACAACTCTCATTGCATGGGATCATTGGGTANTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCNGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGGTAT
+
A5/#+5=+2G78D"2BA3'%#7(>:3-=3H:(@7C+*3B#$(D=-(-F6D$>83>(:$!==3!#A,!C'<E/B'#8(1,4%=?G5*);G6!4>-E'-402F8?;53+9-H:GB0?$-F(,E0@1EGAD)&B-@"EH?&=2;$6?!D3,6>%2%%3*,3?><4
@r649
ACNGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAA
+
"**+#*&*%&"("+"$$$'(+!$()'((!("))$""!+%'$++$$%*(#&"+"*$#&"%$"*#"##*+"$(##+#)+")%+*(%'!"%')
@r650
GCATCGNGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGT
+
8$B!>+;!(6B5A*)5.7CH)/B57/>;C'974+.F%>&<
@r651
TTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCANGAAACATCTTTTCATCGCCAATAAAAGTGGCGANAGTGAATTTAGTCTGGATAGCCATAAGT
+
7+H/0/;'+<<7+9D*(C<!2#@/*<A8%+$1%!7#+67H.-4$5F,1;18?"#68-6:%FD3"H5F>%?D3-C(E:/-2GF2A-9<'#)'A5.51H%!0*:*430+/4BH>';5,:@7?
@r652
CAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTAC
+
/F3<F4>F$)F2C69)H&C-,(7>>D:"#=F5(D83,H1-%A8'9
@r653
TGCGATGAATCGTCATTGTANTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTNTCTGCGGNAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGA
+
0)G87%#'!!8(%H*!>.5"@$3D42C418'=53=79.(H9BF;2'.7"0C2'AE*=+#,&=5?5?F2H:A/@B,:/33?6:""@AB.+,(C0EC+1D!&"23G1;<%.@;E76F.3F&14*6GB0D:$-;%7;46+H#*=*".@.G);'/@/?5
@r654
CGGCGAAAACGTCAGNAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCA
+
+9"&B"8=3C:96*@/>G!.D.5H/7%+4A1(72>,1!+D)10,H<=C=(7@+@,$15(H88A
@r655
TACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCNACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATNAACNAAACACAAGGAGGTCAGA
+
8)A<%<"C@(=00B>D57;'!4+A/9A?!';1*/!20D(?'B!'7ECB@18H01<&';,F>4*3&>"(;2E;9&3>/>'<G5.62.1-1<G/")>9!0&EH7!G9"'B"0&<-:8DE'F@8@01'*7G
@r656
ACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCACTTATGACGCAGATNTCGTATTAATTGATCTGCATCAACTTAAC
+
/@C);,$('8+.)FF/$(2'CEG33!:*!E!).27!>C5#"209>,7/F4A71%,2BDE+><D@015B4AF/:3?CH)5GA'.G:5$F6DF'!),3423-=%)'C'!=84=%-F)-,*$"?.6(-1H%A
@r657
CAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGCCTGTTGAGC
+
1/HDD1!$37!C.&?*4'H@><'?7@;=F2%=9;D+0:A!<3%")2HH674--E
@r658
AACAGGCCNCCATCACGCATCTGTGTCTGAATTTCATCACGGGCGCCCTTG
+
)G'<@>F&!4+581D4:$GGB+E.B;."-'+%-0<&-&#D'G?D&C3F9+C
@r659
CTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTA
+
!4H4H5(2!<=*8<<,,.89)4?@2;-+&#&+DAB2CH"15F<1F)64,6.>5659/"0F62!-5<H@;>8D)!D.:=,D@D9C#',;18(!?H-4H-"0%&:4@H,<DC6+004'/@8":6+F%(@H(C&46#<:<6*,;'1>),C)/%FD1&F7"+8<2'@).?%HD=$+$1=;2*E0HA=3B58.)!++"H"<9):=B-(9(,@C-<D
@r660
ATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCNGGAAGCCTGNAAGAAGTATCGGGTGNTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGC
+
<*?5/6;A,84)("3'*2+4*=>$6$)/;4*(78CH!CC/*6@+0=B=)'/F+F>%<3BG!%(<"3@9"@%>HD&4&*@4+0!=0*F-E4"3D7&440@3.40@E@A=B'$%=F0)608524C>5,2,7/8*$!12/0&;D(=:CC'3/+
@r661
GTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGA
+
@F'A$D9F."7BE;D<%H2$8/=6<):%.5H($#;+8#3"#
@r662
CCNCGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGANAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCANCGTGTCGGTCAGTGGTATG
+
GG@@A3#5'2;G@3:2AE(&2/(@6:85$1:5,;;C5<7-;9D5E/;)+6<%5A>G@!'='B(/-9%#'/5(9.24G>@#($##<G+4&B:H:6*6<7!@<
@r663
GNGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGNCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGNTATTCAAGGATNCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCNAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTAAATCGCAGACAACAT
+
$)=D7%5(*9+)7:=/E)7,G9/H<CBG'48)+@F,-%633>C#)@<HF2:5<H=9)B-(AF)"1!4)694'G51F&$#.5,2!1/3;91)$)9=6@6:4@<1E$==D29-H>@D2)1-G!A,-A,(*G<86?&"<,;1,'(0D3%8((CDHCFA2$#CD)*#%EF)AG?7;6%1#3407-"H5&:;C@+=)!.#&G=#=,C'2;G98,5@'F>'!&:%(")E8%<C9,2'?"64-H=&&D.8<'6(5+H(#.%!1?'4?1&4A8)33#&CG7D+%7+G512B.);=&>@(E+='C65D)%,(;C*?"!&!G'+9!CG3/&96D4F)-B$5>D4>#B#F6A!:5:C%*2(A,&55&99D42?%%6''")B.*A#>@-!E#+20.A<"$,8*:-02131?4C9CB"EFD,G56D.7+0C>:.,#)*>&,,.&(',2@'#@";?4)CB%)A9H9AF'A@&0-HEH?E,E318!,/B=).G*0G#--E+"$#1@"AH45A+?762B3DAF@:06<D?"-"G?4=)<A?8%99:DG$A8);))"1+<D;$H"6<
@r664
GCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCA
+
7,-$H5')!5G.)A7$@2%2&G1$5@6;;2G0=++=;'8F=2
@r665
NCTNCAAGGCNNCGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACNCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCANTCAGTGCGTGANGCCACCACCGNCTCCGGCGTGGATAATGCAGCCTCCCCCC
+
!($#$*$)'*#*!*+$##&%)#&(&*)+!$()&(&$&%*#("')#+!$%(%)($&*%&'&$()#&''(#%''##+)##""$#$!($$+#"(+%)*$!#!&+%&!")&#*'#*'%+&&*%#!()!!!!#"&($+&*"!&("+**""("++#(!#'+*"#(""!)#%*"$*&"'#+)$('$!(!#''"(&))$#+')%##!+'+)'$#&*+"++*$#"+!!!%&(!'#!+)&')%**+*!*&()&'*()#'''&'+$(#&
@r666
AANATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATNGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGNCTAACGTCAGAAAAGAGAGCATATACATCAANTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATNTTGTAAATTCACTTAATTACGAGGGCATT
+
&*&+'$"%&&(&''&!$"&)#($!'#((!"+''")()'%)+&##+)'((%$*$"!$"()'!!!'%$'"*)"#)#'#*%)!*($&*+($+)$"*+(('((&"#"#')('"'&)#+%(&$*!"&!""*%!")()#+#))++')%*&"+$!""%*"!((&%+##'!&$#!!)+'$(()#()!)&#*!!*)+)$"''***"!"*&&#)$$#$)*))*$)$%&+
@r667
TGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACNAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGATGTGTTTTACAGTATTATGTAGTCTGT
+
#B@,&8)6$+)7:&+!9,7'CE!.(;#*H'5'5'H,.B(2.,4(8B$D686>AA#@)+G2GA+$2$G<BAE,#B@80(0&,478;%%4$74=3:E8B#::)/<D/!;+1=;F1G;>#&88)3@(H@(/%HC"G-4:>6E80FA7
@r668
CCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACNACTTCAGCGGAGTCTCTGGCATTC
+
3,)2?!B59@!@7"7+&?9B8.=7-.A"/*3*$$'H<=B6>#?$>0%@#"C4)BD+&/'&:
@r669
TNNCCCTNCGTCGCCGGCCGGANGAAGACATCCGCAGAATCTGGCGGA
+
%$!((')!'(%$++*%%'&&#%%'"+!#!*%#("&%"(+&!'$'#+&+
@r670
TACCTTGATACTGTGCCGNATGAAAGCGGTTCGCGANGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGT
+
=7/6H5.>G/E%><F<=*5(G<2+++;D.C%.2BC:2=!:"=-EB/=%D<=6,9'E!#89:(AHCA"(<'G62$<.,&H5A531484D2G9&
@r671
NGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGCGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGNGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTNAACCCTGTCCGATTTCAACAAAACGCTGG
+
$43(?H.?G'4%B0.45,$%?:"&)+9<*BHD*/68.7DD8'270=610)4'E76=3D&:4+4B:!.!)-!0DB*@1FEF<.=,A&:551.GH.<.=9=H3'G75:/6%'/4!&,:;99"G;$?$BC)='0C39"7H>!2+.)(8*%:##3*%(7:AH6
@r672
TCCCCCCCTTCTGGGGCCGGACGGCATGACATCNCTGCGCGAATATGCCGGTTCTCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCNTGTTGCCCAACTTTACCCGTGGCAATGNCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAACTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATGTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGTAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGA
+
B!*/H21$:9A+022/5"3%A%37%#)@>CB"-=7:4H&?!!@7G.GC.H*.,6*6?$+CEBC>.5?-G&B9/-*7"*D?2=-41(%F;A#?).%;*!.B'B9B(8@.6@9$<2,")4$E+G6&$$*68G)*<A*F+)(*:$'<8:'7$<F%.(=6!BG'!G#$,:E20$#<3DH!G19@/40H<7/&(D383<AE%*$9/*-H*0D9551,A7"!&<A*F8G08CD1/1<3>?=4>/17;=A2"-/73)'A1EGHA"-G=E&;<%0!@:18.;,@@.>#B,2$#)*"1C9#16DG853,(HGE#$'5"&!?/$0#-'#;$&@'D9!2C"0E$27&=92;':3;?-%C%='">;C&$6!)86:($?<2CDB)D
@r673
CTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGACCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCNAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACT
+
G/(0;<@5+1@.FH&E4C(H+"C1$4)C'//G@;3#A351#6/'"8".&$#-AF7(%CA(1'+)3/23"70,-.>E=)6+7$<&8.*'514:0'.E?+&-("(1C56!9=),01:"6/H2/>)A"F9''(4-FB320/5GB557@9F5"!:?125D&,::BAC'@
@r674
TGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGG
+
>4B%&1(2-'2-(%4@>/G7*C,:7+A2HE?A8/:)%!F.;ED(?;?+H,4E.7B'+<7-H+335%&>$8C"2-499G1*2%5CH/G;+;?A';+&6:5(+*7GDH%!F:0%&%?(7!2/6F#.H?$G:-F8F578
@r675
NNATTGTTTATCATAAAAAATTAATGNTTGAATGTGATAACCGTCCTTTCAAAAAGTCGTTTCTGCNAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTATGCTTATCTACNAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTT
+
!&(-E=$A8C?;A)=3&'&FE;((1"8'<A9/=@+(H?<!3!5E#C6;57:@4/;"H::$4F7@"2/=8C0F/!!!($<B1=*-F.1,&26'.(/F"GB).3CH6!A#1E3+9/=,86A&)!4&/,0-/32:FD=+8<D0G">&&9D++EH3"H</6>002-'>8",15CE'+$G'4.65BE.93:#6'D30H3:*D:E9/B,A"D(H-H#/F$=.
@r676
GCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGGTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCNCGT
+
@13$A+,9H64H=AG((A5)#03F2(GHF532+)G:@?..>).%9C1C,7>E>/1B+1.A7'+5E=;H8'%@D?04(+F;!$&7$#$F&G"!9H9AB<E#FD916F;?'8$%!4&G3#0$'0/!B(1?*B71&*04$0EA!5H&+7?:G$21;:60::6-A0C&1">
@r677
CAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGAACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAA
+
&*+")&$'*"&*)#*$$%(*'*))&+#++#$"#+)$+(")!)#&")#+%&'*("%&(&%$$"$+!'&**$()"!**%"("$'!%$+'$!!#'%$")$%(!$%+$)$&#*)%%&%!&#('()$#
@r678
NGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATT
+
00$1,@E8''@@2,F#@:7G<44GG$0'849C*?E#-#7298.G&6HG92/<:AB
@r679
CATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCG
+
B,./#5"&=@H,6H"G/H57%"!<B;7"5-9.C"8);-86!D>78%&17=4+;&EB'!@E,B:!27@*A'*-B4E:7$63C$?FGD(E4H$"#$1,??#C:HC!H#2<-)@4D,21@>HH&",',G$A??!8B=<,+>#!&1)CD=/1&*538A3!!B-(-B.GF!)E@7,1+#;0G-,6H&1&7.):0F9,'%!B=,1A?*5C<;1-)GG"2C9C%5F'"GF>@@*/$.+=3!3&B@?:
@r680
GACTGACAGACTGCTTNGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGC
+
3#DD=$C9>%!<04'#)##E:D9)$@30*)#1BH&!3:,-"@=8#+?8E%C,2034,'./D@@3662-<-2E<7%F>/<=>>!7G=+4.*G#A445$'#4;F)57.8+D=(E-H>9,:,&39?D&B,D7("*=9',A:.BFH00=/9H40B=+'D@2#@6"#D/+$8'2DB=.).F@93942(.?F!D:0H>B2<
@r681
TTNCNCATANACATNACTGNTTNNAATTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGNTCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGAT
+
&"&'($&#(%*%%#$('$&($($&)'+&*!#*(%#!'%(*(")*'*+*$''+&#!$*+"#(!"&)#+#'!!*!+#)!($(*&++(%%!#&))$!""*+'("'*)(+$#)'+("'*(*(*''!**"#*$*""!'%)
@r682
GAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCGATGGTTTTTTAGTCATAAAACTCTC
+
$+!(#*(%#&*$&'%")&&+"*$&)%+(''*)"")$*)''&$$$+$(%%"$(!!%'*+#%
@r683
AGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAG
+
.&-8#E'-F%*63#)D.24+(C"1EE9'8=,88,'$BD$H@E,>6)#?G='"*F&F7%6:H0>G!<#:*2%>E-/27CD'9DD$EDB8.")>82B-
@r684
TGATCGAATATTGCTTTAAAAATGGCAACCTGAGCCATTGGTAANACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTGTCGTTG
+
B2"=<?1//"4#AH:$B,<E+$""@-!"?%@B/.5<:F?41,2!'77;#CG<52E>:=D=)C<EH$)#2.>@,3.%)<$")';@$3@=
@r685
TATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGA
+
F13'35D80C?*CC<43)H-+#6BAH2%"!E"*;A=*38$"$=5=F1-0'1A11(GF@=-20#"F:?H6+#7?!#$?>G7@A=G-9$.:',5?F7$+&,47GA$#B!77C8)7!+"9/0.;?$-)=%)7G3/@E@=#8,03%89"?8856(5B"*
@r686
TAAAAGTAATAATCATGGCCNGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACNAAGA
+
+4"?;;C684-!<##D;/F;**AD+C+5#>#G=-!2/;<C0%5GBB!36D=F2$'C3*'=D:A#:*EFA
@r687
GCCTGTCGGATATCACCACGATCAATCATAGGTAAAGCGCCA
+
E*.A?;D2=D%0;ED)A<E#+:G!<E!4F4).9=/!5-$F;B
@r688
GCCAAAGATGNGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTNTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGNTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGAT
+
:'*'%>#91H."@6+F!4!9,@9FGH91,-)947#4<1D'+'DE4H4?8/H!8#)B*&4?-$&'"#E:C?:9-9+3'9C%5F;=$'(A(GE/DD/?H,:C)C%)+<-/:0EH,D.:(8(6C,,,D$4C75@&7#4$D!DG344?*(.C1:"5(8E$<-/@@G:7.E"='73%3,-B(H7*
@r689
CCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACAC
+
8.";;;C00D/./E:F2.2(6D#;@#H/,((&F8,7F9<=:$'6/;02=(7!F@B+/;/*,@<E,:H0F-?8+2<6B)C/353D
@r690
GTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCAT
+
51)((-A.<&,#4?@;"%=&>(3&:%1)(HB)*3<#BB;1
@r691
ATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAANCGACTTACTCGATGCACNCAATGGTGTAGCAATAATTGCAACTCATT
+
<7>BC#:.B&,'.2H/3/G?AF9<//"!AH(8/02(84/5'C$%ADDF48"8=G#B4&,<:'@@0AFEH?1.G<7'?;G14/<B$3;$#G1E-?%/'9:F50%9=,1FD&62.D>:B92(0(+>2*>GBBA->?&@G,)%%&GCF+5?)8.G6BF.>&>'AD;:2<%@<?22,;*1=/BG!65;;071;*-B1@*9?=(*H-:#FE)*
@r692
CCGTCAGCNTGGGGCGCGTAGTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGC
+
:%#@H%C=2@&>H''9>9*?7'DA-)4!7G?F..6#8.EGB..?0/-G@>#9-4@4EF")>?A?C+2<<D@3G32F3$/H!F.&>D0,2
@r693
AGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACC
+
'H66>3<:$,$:@3%A.+FE$$3=.5B:(9/*=@;%BH,/?=EF%A%(E&
@r694
TGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCAGTCTGCCATGCTGCCCGGTGTACCGACNTAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTC
+
*?)"C#H;7+<?E%C>-?>BFF:12',4:'>$)"=0%6#;/30?%%93/5=.,?H946HG+"/21E<#G&*-C;3-!!@/;B2(.9G$:3-@A*"AG/<5#DH9'?D-/A@5&!.'/"8*/&0$BEC+!-3!)A=;F''.B2#-.,H37>4"7&1+1<;!'4@
@r695
GGACCAGCNCCACANTCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATNGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAANATCTTTCCCCNTCCGGCG
+
EHB/D.&65AG:,;*;D%)/?$@<2,$977-24@1(#6F:@9DH@+"=C3@H.B8:@B/#3-B&+*$(C.G#E(:B?6">H"%:%@C1/-D>9C#A)F<B:.0'F;&B3C59!1A50>>)->
@r696
CCAAAATGAATAAAGAACAATNTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATANCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGA
+
%**+)&$#(*%#!"%&%%(&"")%$(#&$!%($$(*%$%)!)!"**%!$*+&''#$)*"&+$*+*$(#("+"%%'&!)%)"#)))#++(&)"#)($+"%!#"%##%*"+*#%"&*+#''#!%*(&*((%"*''&$+!))'+()%$#&&*+$+&*&$&#$%"&!"+*+&')%#(""
@r697
CCATCAGCGTNACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTATATCCAAACGGCTGTCTGGCTTTNTTTGATTTCAGAATTAGCCTGACGGGCAATGCTNCNAAGGGCGTTTTC
+
0:C=#?.G7F?H>38"(9.9)F13EC-&A9GB/)2@5';)@$9EG53%=$%(')C@;G?)A9.E8G92;D(E.F/*E7<C"/1@&F6,#:,+2$'"*70/656E@G:H2-F:;114A<2778=:=1&C12FD!&*
@r698
CCGGATTAANTATGTCCACAGCCCTGACGAGGAACTTCTCT
+
+!!&$*(&*!"*#))$!+$&*(#''(%)&&"++!*&*"')!
@r699
NGGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAAC
+
&.F4(<."C:77-&='=(,*C!138*7B;-2C70/2-5!1:>6?E"=$.74<;A#(G%4?2+#.D%ED&B2(&%42*?=4/*A+9.GH?61*;>2D2F/5
@r700
TGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGTCTGCATTCTGCGGTAAGCACGAACTCAGCTAGAACGACAAACAAAAGG
+
6GF<9E1!="65604;(,F+F0C6!'1?+A"!H/(>,!/B%/@D72;F"CE?/7&-C<9,-4#31#%?E:+%?/'F"4;">3984#C65.:#EF?:D=
@r701
NAACGNTTNGCNGTTNAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATANCNACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCT
+
")('&*()%%'!%))!#+&!')"(*)+#%!)&)&*"+)#')%+$!**+%!+#!*(+!*''**%%&'&&(&+#('##(%'%+%+)!%($"#)#"'*#&"#%)(**
@r702
CCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGAC
+
$+%#("()#%##!#+!%(#)("*++*)%+#!%*!((*#$$%)&#&!#()!())$&$&%$*#*+(%
@r703
ATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATC
+
9FH&=;+<64,91H4G%B!2$!@,32G,49$<;*C+="H!<,>
@r704
GGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGC
+
8%AGF#85-#@H=2&46:DF#!+BAH1=+!+FC527&>A'.*B*)8@=?:
@r705
ACAATTNATTGAATGTATGCAAATAAATGCATACACCATNGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTG
+
:63.9+H$@:):$5D!><.:C+7=&6G1$)<">?C%1CH5G)HB?D6:9*F<)C,51D0>$'16,EB4DA+7+09"=,!:5F==F*B)0+-@?$;"
@r706
GNNNCNNACCCANCNCGNCCNANGNTGNNANNATTNNCCCNNGAGTTGGAGNNNNAGNANGTGGNGNNNNGTN
+
"$$#$"#!##$!$"!#!!"!"""!$##!""!!!!$!!!$$$"#$$#!"$#$$!$!"!!#!#$#""#""!$$""
@r707
TGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGCGTGCCTCCTGGGCAGT
+
5"9&&HE4#C#4E@@*7=?"'"CH&9->",>#62+2*&'+:#A*;,*(49G7(#
@r708
NGTNTANNAANNANAAAANCNTNACACCNTNNTNTNGNNGTCGNANNCNCNNNTNANNTGCCAAGNNNNGNANTCC
+
""#"!!#"#"!$""$"$"###!"$#!##!"!!$"$"""!"#$""!!!!!!#!""!""#"""!"#!!"$!"$"""#"
@r709
GTCATAAGAAAACTAACCTTNGACATTCGATCTCCAGCACATCAGCAAAACGCTATTCACTCAGTACAGCAAATCC
+
""*%&+'*'(!$#$+'!'#!*('*'%*!($''%$'&&#"**###%"(+'(!$#!*(($%''*)#&)($(+&!#++$
@r710
ATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAA
+
+!%(++'$'&%""+%')$$)&(!&"!#$#$'%"&''#')")*%(("'((+"$+%!#++++*%*#&'*!&%$'(&&%&%
@r711
CGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAAAGCGCCAGCGGCTGATCACCTCCTGCTCCNGCTCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGNAAAC
+
2-6$%D-$887CF0.:;7'::=;#&A.A2$0@=9"!6)8/0%71H6GHA2%-0E5C="AD=FF!&<+HHFB5A0D//.0@,G&7E7A26"(=(HD-&FF6>8'B4B2+?4HG7A)6??C>->8=FC"!,)!"@D;6>F@D2'6C1"6E4B0G-%<*B:BED
@r712
CGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACACTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCG
+
9,*=(#2&<$B9F6,H@"A&>5,A195'F<AE3@H-?AHF3:1&'>D+#C)!96B.9$7A"1,.8D/1%;"02A&93=+GC6=91B11H>80D>+HE-7685>F;:&
@r713
ATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCNGTGTCTGAATTTCATCACGGGCA
+
?A8'@H6+D-9E-(;9C1EH7)-;.(101#!%-:F=%%&3CHE*-%4&&&!H?'#4:$G&9?F>),;H499,0?4@1&,D7(A@.=1D/@=E$1>!=9=
@r714
ANACANTTGCACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATNTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTT
+
($"(%&#$+#%!*)+))!&'+&*!!!""!#$)!*%#+)"(%%!*"%)+)!")"%"!"$)&*%+$""*$$'+)("&!%)*($+)*(*&!+**'&"!!"&$#$%%("+&%((%!*#$)$*'$)"("*$$+
@r715
GTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCNGAATCATCACCATGTTGGCTCAG
+
B;H9+8D?@(%=>>?0F'6%1)'D-8'8(2=%!)C'47<'F$*?/G6==,&B#0/=8@:=$&6-?%H,2@C+@CE"A
@r716
GAGNTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATATTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTNGGTCGGGCGAGCGATGATGC
+
5*H%;=A+11%0%<'G,E6#+FF:3/BH:!D,*2G6G=6%&/77#1>#5=+6?G=(*067(82.&-907-A8AC/)F;?,(7?/95=9?=9C8D2-F8%9E<BEC&+BB':7$=0*.@/)'(98$,?52$F;!=:#H3G!"5/8=96&*0>A1@9G9&:EA3>9HG..3A(*<-47!D#050@C*9EF'H.)5C$.$&=44>-56E!;!EF<:5>C97(-5F=H),-87=(H(>"*%,/H<H';/.6B$C(<6.-4)A5EB(+0"
@r717
TGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCT
+
)>=5)A#F"0216-'111?.H&/B2@<05.;367()"3'*)F'>%1@#:$9**)G081F2,))$1EG$F,*)383,@+:./?';@%C-=:F$EH5:#
@r718
TCGGAGNCTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATNAAC
+
<B<#;HE"-*&&<?+;8C6H;!<19<A05>9$!7=41C;-;G@"",B5:)3-@5!$;>*#
@r719
AGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTNTCATTGTNCTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTG
+
04+0/+.B:7HB592,A,@36;B01#0G*>)A?%<F*HE%?/.,!;%B007C;ECHG33+$)8HD65@4AC0F(D=(D5DG-?E<,+&+AD)>+B*5EA>E/HC0;H2@2H.(=F/A2)9G+>A-(;"2H?G6;EH=%)'7AD5&:6.+,D1/3$AE#.B%!4GB%G'92A>5"2:=;:1='5,3<H:847<AD:#)*+;?!,D!#7*9!7'DC&?()1>D2-&A8HGE@5:$
@r720
ACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAAT
+
-!&$60(+06-/5,&2$$:E.'=C*4F:*-D3':>H0@F4-)0'8!95=E+>011A%!?'8(F-,?3!AF@G"=6.>;,+C<
@r721
GCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTG
+
'++&*")%!*#"'%+%#''%&"+')*'($*+)#**%$%!+&)")%&&$(($)&')*%('*&)#"!+'("%$(#*+#$$
@r722
ACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGC
+
;&?18?0G&D=3'.+D8&%=00-,/8>H0/:F-%("$49C>'-@ED3/,2DFHBA(>?-##2B
@r723
ATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCT
+
GC03=20.F.1!'G797E>*3;?>96=@H4F/!#-71"'+1'5!<D.(7=.
@r724
TGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGA
+
'+%##+*#&%*&%*$&"*+$#$##"!+%#)*+"$((&+!++!*$!$"#++$$*'%)+&*+'!$$"%$!*+($('("""#*'"%'&&(*&*#!+#$*()"'!"*#(*++)(%&#&!+!%!+""'('%$!!!'*"%**#*+!
@r725
AACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTNGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCATTCAAGTAAAGANTCGGAAGGGCAGCCAGCAACAGGC
+
<*)5>?,&<E"!-'A$DDB(3G=."G4-788GA#9/!C;#E2@%7,;@E00=E&;(>9A?00<>26#-+*A)HE!)BF4&"B2%B7"%.?*??C0<FE.42H<&"C?B60'2(<(E-7-!;CD/5;2B3$B3@&#"(==((D!'63&$?B7+7E@@&H,>(>1'2*)5554"$+@500(@6
@r726
ATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGANAATA
+
1F)&$/D99C-7@//:)8;.C14C(*C@(*H=885?4'D<-E?88$#2D,0&(".%"@&/48,
@r727
NTTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAANCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTT
+
(GDB)B87979#,1""#+4&98:0B>8B4)!8)9(@/.@C#'7>+@#5>9:B69:F2B>.(4<;F$@1F+8.>!HB58!E@H8@A#C"C606G
@r728
TTANTGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACGATGNCCACAGCCCTGACGGGGAACTTCTCTGC
+
&&%()++"*#&)**$#(#'$+%"%))#!*#")!)(#**+++$++'"!&'#*&%*$##&(%+'+'*'#('$(%#+)&+(%(+
@r729
AACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTA
+
36!CGC6*?D*(27$?.2'$-"<;'+-226E1@6#@01@<5%>/:*4G2B:3*.)=/-C#'2";=!G;)5
@r730
CTCCCGGACGTCNTCCGGAAGATGGCTGTAGGGGTTGCCATCCAC
+
G50%3-$"%1)3=&'+-4*0<CD+DD/0>:.FDHCD$.536'!+$
@r731
TGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAG
+
>0")8(B8$<!/6<?"6HH-,<(<$'!/8!8A"63D:2D>97,7#F-!4->8+:$8"9GHE"=C*D(;6*)3-DED"E?!=748"0+
@r732
CTCGTCATAAACATCCCTTACANTGGTGTGTTCAGCAAATCGTTAACGGCATCA
+
82%:02$;=0<09#=5$"&)/(/;;B-(DB@C'#=F$E2F&02$3<C!.@,>(C
@r733
NCNTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGANTAAAAGGATCAAATGCACTAAACGAAACTGA
+
"*!'(+'&$)'*%!!*$+*!%+&)$$$&%!#**!!%'#!$$!%&%#'**!"&&)#"(%*(%&*()*
@r734
CTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATAC
+
;@=+<!@/<D30+'D#2-?.7B)5F*$1946014%G3A*%
@r735
ATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAGCCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTNGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACNGCCTGACTGCCCAGGAGGCACTCGCNACGCTGGCATTATCCGGTGATGATGACGGNCCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGNTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCAT
+
107/%4$(2BC=D!532/%'&'A1@9#=<92!%H84G&=8B2,<'D5=+'>'?DD,?>B?=6"G47:*.A>5C'!*FHE.%($)9H2D%1:F2F-/.3-3C3*94:B,51C57"H(&+/<'8.,A32:1<3*.9/B4B?(EDG'3E*3D8;30".)<,F3995'$)>3;?<?D/;*'A<-.'25(:*=F3?!5D)*+%G1'BD$/8**!*@"C1G2D?($#-?D#6)"?"1G1"0G0@F->F+==A48:;5@>(H56-'5)?+8$&H8-69<E6>?#(.=@#%=A@52A!7$6&:'D+,*<
@r736
TGCAGATGTGACGCGTCACCTGACGCACTGAATTCGCTGAATGNACTGGCCGCAGCGCTCGGGAATGATTCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACT
+
8-$%0H-B%)=3>&=."-8%A()&5E8'5:;3A7G$@)E=2$F$+G1%)/B"D,#":2!7"G1*9)*?E;81C:784/+27EB=86?1+17H=4'*$C=@2DD<@;C=('098;$H&H->D-.D/$+B8*C
@r737
GTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTCTGGAACAGGCAGAC
+
6H-7)"")"(>)4%,%8E?;-55C2:@B11C>;<1(B09F+0H(*,">960(:>$!-;&?1%*
@r738
NTGACCCGACCGACGATATCGAAGCCTACGCGCTGNACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCATCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGNCCGCGGTGAAAGAC
+
$8HA="%(9#*B*6!%&7E*:)#+'8$!HE?>B;?8>33=;B#:,#&$5#0:B2F)0!%,A/,&;";'GF&>,.,%1&;5,>:<!&C7GG2#H4$65)F4)*%HE?)1G6)%*;E+=<C43$2<82<'DFAFG&?,B:G<H"00B+F8?H;/2/2BA#<E8/1,&<G$B#
@r739
TTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCG
+
%D=F74#4/%;4"$C)7?(A*;G?G)"#2@2%,!;%/@#'7C3@+DC,)&;HC)#
@r740
GTAATCGACCTTATTCCTAATTAAATAGANCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGT
+
8'<%#<8&4?:!E,+<<5,(HD)=E9"16A"$"B%?C.!A)#0E;)A,:2:DE9%B0!6'G#086$D#F%@6:*/+8F348<%
@r741
GTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCA
+
GF257G2#(5'=!.2.!$7A>>//C9@.FB-('0&6HF2%&5=-%%(7(<>5C)0G80)/F)7()G$50="(3;809<?>%A#>F?A8"G#+(%G?%4'+5;=2H7B+1,8>;HE=$"9=>C.CC01$6=6D4*31A-2+F-HB.AAED>/2BF.
@r742
NCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCC
+
&*>#D=E?.B+1*/D;$-8.95=80<8=$@4&AB=2/5A#,E2/%92E4B5744%-)*7E-:.&D."1*#7%F?G#."<#A*0H06C7B',6,EDA%)0@$8=<H+D!/7>%D.2-'A(9.C+"*F(%7?9)4<)D("%3:E%=?&B"FB($$$3;$*9>5?3868D;'D+3%2G$7FH:0
@r743
ACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGT
+
-A1A&:1H5/<BBBD'EF$&/4&=?(2.;C)#$G%'D7@E!?4!-0.,1+"&5=B7F@7/.$"2%BG&3=>=A!1/2HA$%/9G;(&0;080A7!#$2E7
@r744
CTCCTGTTATCAAGCACTGCACTGTTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCACTACGCAT
+
1,D%@4@4G/B931D>!4#F#<2893&.#$@"A882A54""<E)'>E)."="1>7042#,H>)$4?>39#<@A18B1*D0'G&62C-5,H!?-D1
@r745
ATCNGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATC
+
(&#%$+*(%%+*'('*+"&+"'+"&%$%'!"###(+#)$(%!!(#)#"*!#"$*$'#&)*'+!!")$"$*($%+&'%'!*%)%&*'
@r746
ANTCCCCTGGTTCAGAGCTGTACGTGGAAACCATNAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCT
+
/:D*5C+D5#&+@B&#'"@')HG&$B+A/CD<%4-1'$:*,,/$9,E$+)&//!)!7@!-@=('"=&<'3,31DB:HE-5//:%,$+>%<>1@HF)*B;?=DD6,0+G=42E%&G"*=&@=A;(.($>2.*D;3(E<A9.B<=5@F;+2&
@r747
NNATGTAACCACAAACTTCCTGCCTTCATTAAGGGNTGCG
+
!"+!+)*%)#+('$$!*+$))+&''&#&'!&!&%+&)!#!
@r748
TCAATAAATGCNCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATT
+
B.3*%!1#G$B@#<E)@H@F)5+<<*"5<,$@8#<94'0BE<0<@78/6>6,4
@r749
GCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACA
+
:=*%7('4!=)<;"+/>/G4%-==DH1.B-C3E2(0$-0%>D>493C!?&<8
@r750
TGAATANCNAANGCAANAGGNCGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTGTCTGGATGCGGTGAACTTCGTCAACGGAAACAGT
+
*&$')!)!!*)(')(#&*)!"+)")"++#&'&!)*'*'%'$(((+#*!'%))*$!!+$$*"%&')%'(*%+$()("'"*!#&(*#"&&+!)()+)+')#!+++&$#))"!)(#"&*!+)+)#'"$#*$"$$$)$(#))&$%)%%))!(&+()%!!&"#!(%")"(**
@r751
CAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGA
+
$5-F3==!"@!3=#4?@/+:H:&6"")A5C*G4)!3A#%0BA"C#&B.D;3CF2&=(>9
@r752
TGNGGGCTTGANCTTTAGCCAGAATTTNTTTGTCGTAATCGAGATTAAAGAACNAGCCACCGCATTTAAGCAGCCAGTGATCAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGAAATGTGATTNATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTNTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTNTAGNATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTG
+
'#'**(""$("#+#!$#**&+$()%"("#%($'$(')&)#**"+""+'")($(%$%!#"$$&''&(!$)***(+!+''$!%!"*#$+#)$%!$%$)'$$!("+#'')'#%*!#&"#((&!$%"!*&+$'"#)()#"''"#$"&&)")("*(*'*&*''$!#!'"&&*$""'!%%%&("$("+&*'#""$#!"+*((((%+&!%!%!"$+%(*&(!"*$#(!#&+#'!!"'#)&+)('("(#")&&*+''#"&$)$&$&&%#+$%"#'$&"%))&)*('#*##!'#!&#("!&(*')'#&"&'#'$+!++*+++!&'&$#%#&)''(
@r753
GTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCC
+
E'@"?@8$E1)G?;:'C$($-<7BHFG8<%+""3(1.C=/D'*>D<GF,02+,.,3
@r754
GGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCA
+
;F#2.G%=;@CFC;C8/,'B7.%BF&,CC@!-B::59(:1;>%$<,?&5DD<F>#"-;C&D'-"<>0+#)&*07C=)<?"E4B#G%!'&%7&/G-?'76,E$>A'!#64#/0'#*7
@r755
TGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCANCGCGGCCACGAAAG
+
45G-$G>9&D:('?H/15.-%AE/1;#'B"F0>F:-59250&64*1*!DF*B%,.-
@r756
AGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTAC
+
+/$H8>1B8B&4:36#=2;C"#933GHH,CEE-3$=102+!@E31'&:F5.6-'C<@!"1<;;#%3.B#(";9:#51G7#7+(+-9"+*%59E3'&A8D1G'$&$+F9;0
@r757
TGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGC
+
BB5=6C*3<'!8*0AB$G)%10%0044%6&-F=.@D5A<F*:+33F;B"=/A=&"AG57'GF$?0<D,0CE&C:3)2?7%<%B)C95BE&:21B<@H43!3E*.($ED*%94"@-2<HF>/*70+E"9+B9?G-/$H:F3'@7H5(4B%3'G)'$6/+B)3
@r758
ATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAA
+
/(6A00BCFA(5>-*6&:H<>/*0"&G0A)2!1A00E+:4>7;:<BA614;E(.=D@F8G:=%'A7:'2#@E:A=-+A#9<)"GG&"46=)@#</-4A1<D9C,1#?C.3/"7*#/7017730$7*'?2&5A(+0#3=AA@D='*AE:@,1ED""&D=)!C*9!?8*<9HFG:,D*=D75A,!<H>(5(3#<*#>=25/)/5/$!1%>-?#;6849*B8F7*/C?B!2(#$#+8D(6+56B4!.!:$7D!80C)B>F0:(F?#8G'/,4%,;F*E6:,2+>;(9E+/B3,G5,D8#(5$"8:-8,/9&D&H6'.HB-EB7!)$@5@>-26!817?6@,75'
@r759
CTGTATGCCNNNGNNTCCANCGTNANGATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCG
+
!'''"(($(%!*)!!'%"("&*##!#!)*&+*%#+*!!"(()('&$*(('+))+((#+*%%*#%(&(#&#!!)""%#&%($
@r760
NTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTAATCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAA
+
!G;&3+5H;8",/%5-EB-9+$+/DC-9$H6833;!CB14,G'=2>.88'?,)-=D!H/0F50@!:A:("/,E;8+>E3B:7'=A8','4AD9GB;:"'B=$+A"73,:$0G($)H
@r761
GGATAACGCCAGCAGACTGGAGGTGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTG
+
+,6:@C3"2H5D&.GF40)11=.?A=-=1;**@/781)$=12D>61)+??-FB+C72;9&AE""*;+6@#!2C&52B
@r762
CGGGCCAATGCGCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGA
+
&&4#4E@;9A-D&1G27,958(6<>1-1&7$!E;)9*6$2$)/H+*1!0C!H=4@($*&E$):41?)8=689/:A'6,,@CB(:7?F;%43<'=B)2D-8>-*"7H+))(H3@-+7:::C2!>,G?9?
@r763
ATNAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCNATACTATATATGCATTAATAGACTATATCGTTGGTATAANCAGTGCACCATGCAACATGAATAACAGTGGGTT
+
::.+#H'/4A0/,!F2/@H="*@**=+;%?13B=2#E"G(H>($:&3*2/:-G&4F7!"+AD')07AE46.#23C*:'G(2@1A)<;C4FAG!@0B4>**3#<87':!B#:6$)&>B0?==DH<,>&!4C5B,@!(-G9:3G1%>&#?D?"2$@$&7:1$E&$"
@r764
GAATCATTTGAACATAACGGTGTGACCGTNACGCNTTCTGAAC
+
674D!>+>27/B*$%2+A$$C22';)#D,!1$5HA26./607:
@r765
NCGTNCGTTCCTGACCGTGTGGCTTANCTGACCGCCGGTATCG
+
!$(("+&+%"$*#*'''#&&+")*#(&%##'()(('+(*!*)%
@r766
ATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCANGGAAGTTGTGAAGTTCNGGGATATNCCGCTCACC
+
D'(#/:$EG:=.8&@4"6@;&".=!8*',8#'2HD&85$'&");42#;6@!"4A7(:).1,--@?5+-#/@4A*
@r767
GNATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACCATGCTCGCAGAGATAAAANACGCTGGAGGGGTCANCCGGCGTCCATTTGAGGCCAAACGGCGTCTC
+
(,H3/<<E4C0"),A9/0"A$?">,%<B9++#F=:=->((EB)AD9029,H#5<1-$"##412?=G8H"-F#;'-12!,D@;!)/77&3(,A(@%!8'@(49E<<7>@3%
@r768
TTGTCGCCANATTTAAGATACTGCTCCTCCCCGCAATGCGGG
+
2*>@.B2>85A58#&4#,B3"&EE;0"C27F%D&$F!').(<
@r769
CGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGNGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGC
+
B,/22)FB:(:'.#)7)@B+!%,#@1B$F&C<=%!567"94=EH!"96C@.E9-=0(GA?8H<A=A1&==(E5C,HCA0=;+@.F"4AC&/*?2/28%,F6!(=8>!6B/7=3=-@6G829H=$(9GD6
@r770
ACGCTTACTCCCATCCTAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGT
+
%+$)&#*)&!''#"#))+'*'+&""$!'$!&*('$(+!&'+**&+)""'%+***'%&#*(*&+&%*""&$%'$##'+!'*$''!$"*$(+"#(*(&%'!
@r771
TTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACNCCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCA
+
/,3B:?3#1B;1E"8"/+2"H&>?)A?CG;@9"B7:<!6/88%B<$4.?8E%=<63B$76H-HC5,7#5%H)A5<$-!+4%)1(4&(G55,(4?*H>!@/4BC#-9CGEF.8:,-?!@#6F%<:.BBDH0<B#D+2@0)@$$91D&.;'E0&@(;E95A30C<%E")
@r772
AAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATACCTTTGGGATTCTTGACTC
+
7=.=4*&@3/"1)F%FCA/'F;-**'"%C%+?EB;27@$DF$9.'F*'71-)C!&7H"575701';;G#62616#?$,8'-,"6D)+,DE#D"7=&4:'>3H56#D4--'@<)-AA9
@r773
NNCNGTNNAGTGNANTGGNNGGGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTG
+
"#$"%*)!*))%%'%*'&!!(&&!+($%&&+&!$"'(#$%%#'+!+#"*'$+!*##&)##!)*'(%%%+*!"!#(%+%"+++"!#%'#!(+("%$*!"'!&*"!#*#$#"$%+&*(*'#+!)$&*(
@r774
ATNCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCT
+
G*?A7,3(;D!G))@31'BG5.,9<=F1(@94;#BE,$--A$1,B3+/6=5A-!'
@r775
CTGATTACNCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAAC
+
%+'+'&%"+$)+(&#*)*#*$$"%''(!'!''!**&*$*((*''"+($
@r776
TCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGNGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTA
+
G8@"31?)!>/64?>C>*A&%BF%*<&#978$!,5>,E*4DA5<->+D3",#705==)";>68F@D8$<%!>A#)*":<-69G-649>:#E/6,96)A4E.?'C1
@r777
NCGAGAAAGGGGNTAGTGCAGCTCAGCAGTGCAACCAACAGCAC
+
%6AC:0)',<BC##@BC2;'-=&+2!&.%7%B2E,E3HFF)3+5
@r778
AATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGCATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGC
+
/<#/3@G:5<E,HF:?)G,E'(6EEH+E.73F/)&1;A(?>G@<%=3D>215'=7(927F/@$5<9@9C!*6';B&0&!@"6!%D7H@C$51>E<D&9)0=":F5G.%$F6:?H30,6:@91",8)$<E89?5<H&;69;C.4:--
@r779
TTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACCACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGT
+
0$(52F60"%=36&,F(.8%3:9,<@+==9H&.1H4@?%"@9/?!1-1=$G6$4HD!/GA,"804=E>?96#%E+D96@=:*E4%3#E!;)>B*+$6"8#D26,@B#9:.52015A3195;/(/-%?="!5?1<<5DH%1("%B)(.BF.2<G,H7*2@>**;A3%1B!(?6)*!?GDF/,.2*/%8?B!D>(7B5.
@r780
CCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAANTATACCGAAGAGGCG
+
FE,&:H#("B<-&%?H%?4<!78,+01:3HB$:)6&):A)9=$>%7##H+74DB4+?"A%=7'3H,=4&E;D!E(5F1$?:G#@(*1A>6B-F+#:C$14$8@:%8'/128/@8",&/G=0H+<!20>D?A"7GG/GF<B><="3*2C2C(6.*D(8,1&8%?"HB?6?,2;B<E-6:)EH+6*F8F",&"DE%BB54D*+GG$2G%296<&56';2CFDC0E+D,2#"@"6./9=<1/3-9,5?5%$8B%3-9#32$C.,(E&)&418,"2()/;=H:@&!!>H*..?/3)CF<G>/@7"B,F%;4A3>8)3>:;1
@r781
ATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCAT
+
>CG>D*#21)G6!C#B4>-$3$H*G?&D!<3?)0+5A(.1%<@@)40%<02.F9=5!>68+1*?<",)18;><;-C(<,..(<>0D/2+G7$88>688%1,FH?,#/5*'C=CG;B7<"6%DDEG6:A03HB(6@:3E'599?/D%&&(:=5F!0%$";"""97G>?:$;,2?/?:$E(&'%1A$0D.(9;B'%(0A(!>41+G7+<G-CC@?-%/+!;/+E-=,"&$&+5C.$,!?AE+:F4$+B)-%:9+3$:@A9<H73@#C4@;15(;@$3.953!!3";EB(+HC.1:')>72>0-0$'093/0:<+(3'D?H!?=9D2G)21:9&::G@,:@
@r782
CACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTACTGATGATCA
+
H6)'.E@5@>)4.,%C@'EHG?%DH49C*-$(;,*<)>"F3#C;G9;D2#?*E=04"/@=2
@r783
AGCAGATGGTCANAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGC
+
=*)!>?"1%7@2;)1;+>E89F->@3%6H>C%FD.GG5<#3&H:--+H92,GE)G.G0*($AEG.A+%+7,C%?(C$;&@?>+C971?;+?"G>=50";D"#/A<&:G.%B,D.H9-F=AA;C',H.5!(F40:9G4C5C-55>233
@r784
ACGGTGAAAGTCAGTGGGACGTCCGTCGATGGCAGAAGATCGCTGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTG
+
=<6:'D=<+)HA,)(,%H8$;"+HB;.%#-?!G<)E-$7)'=!G*#F=9BH?*/<4''-A":D=F(/*:G&68(.G0-3BE(=&<79G>9>=27*=8=%9)6"+3/5%.!4@$(3-;DCAC
@r785
GCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACT
+
(<03:0!()?F9*6-&:B,5B4(!D'0<3017G,E19+E.9FE"<";..1)%0:<6:G4EE8!1
@r786
NNNGNCAANNNNTNGNCNTNNNCGANNNNANGANNCNNATNATANGGAANAANNTNTNANNTNNNGNNCCNGNNNTTCGNCANGNGNNNAANGGT
+
!!!!$"$"!!#$!!$!"$$!#"$$"!##!#$!"#$$!""##$$!!!#$!""$$""""$!!""#"!!"!$!$""#!#!$$#!!!$!""$!#$"#$#
@r787
NTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACANGAAACGTCAAG
+
#BG>(68E)):85>:F(,<CA;4G"16?#5%G*?G'>6@62=4G<DF3(C;!*<:8B7&:0C-B2=E."76%=>B<1'8<>C45@=
@r788
GTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCNTTACATGAAAATGTCCTACTTCCACACCCTGCTTNCTGAGGTTTGC
+
HB>H'C9$8H<4%.:>4*28#CC:8A'*C5/:;?+3;3<FC/E&:0G"998@(*3-7-><',-"'H-8+%9)FB2!2,*!,
@r789
TTNCGGACNGCGGAATATNATTTTGTNGGGTCNGTGGTTGTGCANTCTCTCTGAATGCCATTATNCAAGNC
+
%%&)))!(!))!&&(&(%!)$$'*"(""**&*$)&'(*&#*")$#)(!('+#!#(!+*$%$(%&"&*+#((
@r790
AGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATA
+
8+D3C?'$C/?<8'#/2(6))H!@=AGE$?F7%@C%2C)*A",;A&F&!B#5&FA;;)6>5"0AD.!/))#9228><HB3!.+.+F@D=$-(103">F-G"?"6GHCB<>H'C7./2H%#G&,&<*;?(/@3B+E8#)*2!<G*H%)H:=3-4*0H9$*&CBG0#*!=-
@r791
GTCACCANGATGAATACACGNTTCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCCCGTNTCTGCTGGGATACTGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAANACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGCCTACGGAANGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACNGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCG
+
&%&#&$)!$#'*$&")&)%%)(!+'(!&($('&+"&)+'#"%!+(#$#'#$!)%%))*+&&)!"*#&+(+&*#%++#)"('&+'+$&)))$*#&(#*$''%&#")#)+$#"("*&$#+'('!#!$(+&')'*&&"%+**#%%)(!*)%#&#'"$+$"''*$"%(%('$!!)&$)((#+"')"""$!'$#)!+")*%(()!%#*)##*)!"(&&''*(+%$!&((!'*#+'#''(*+*""($$%$+&%&"%*)(&!'""$'((()('()**#&#""'!(&$*+&"++#''*"$&#$+"%*%+#!'+*("#'&%'"()'"!)&&#*'(%!&&)!'*"(!+("&'&'++&!%%)*
@r792
AGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGAT
+
C@B:%E,."?08?0<,*1=?62B2>/6(48+/@E4C?6870)@3-'*.G#8HB"9<+9*D!;6C=7011D3">&1,(E54?5+3A0=-H+B>BH=)$%G>)&!?C31*0'.E"%.3&BHC*98
@r793
AGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGNCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCAC
+
:*E#34@'A5AG0A>#!&<B4"<(C&96$?B&'(/$B0!F/()25&@#5';='85E<30=?!47&796C0%=D*F@E?-,6%?*/DC""?-B/+(#GE8E,>>;94,9!G<55#&/3H;8G,.G
@r794
CTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAANACCTTACAGAAGAGC
+
BF+D-2!6A+&"?B"14>H#-041)F,=!.+G;3,D-((;><F!%;61E*G;"2)".FGC(>34,$EB!72)).>?2#:"9.3$"GH,!>91A3!D+&'6$?=:1.A&2?4B@E8<8#-GD'=G;/)5.)>DEF)>&C@5D="623&C78@0";GA79+0<(E1(%G-05)G"AA';:G3FB1)&,:.&E'H=1:?$3(#B&E,4EA-A,(0/'*5170H)F#+-;D377*!A>+>5C:&08;BB'559,!AG;%4A26B,9*A#36=B!$/@45B1"'=D)82>:H>1H0$:#,:&D)$%@?%B68*(68899@EB.=H)A5=1G0#5,%:63'6$H**)H&A!C.>;1'<96)D3@F0+.7E,.H2FFG->E7
@r795
AGTTTGAATGATTAGCAGTTATGGTGATCAGTCNACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCGCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAA
+
/'900(F-1(A'+F31"4=5HA5%=E*$;#9!;H$14&!D654.<',B/F0BC8606),,H#37248E9@":00F'9"(&5-)=,9H7@E:B0,;/"<'5?-A4/2B=HF6,7;?D%?E4/#C<7-3/2=B2E82$A%4*2?+&5)77G?;/1(""?'H4'+,&97#=.CF,?(/"G#:D94?""0>5"0#'0BCFE"C<%'A5((8>9@G4BAG7461/5,!16<#)4(93G.6;?=E-E('F;48*$@$F#DH)==*>&663+0+.22.:7
@r796
TCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCC
+
FC2(B$54-2311E58D:3F<FC&(B4>#)(C30="18-;F
@r797
GGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGGATCGCAGCAACTTGTCGCGCCA
+
,4?252<<C(1$G=(?5@()C=G"E7B."$>:D&-#--+(;E+&#;<+**/*A3A33%''2%.'9A9G(+$!
@r798
TATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAG
+
A/151F!*)G;,")?D4C-6F%9>03*;:3%H%%%/(!$.@7D'53:3G,D+3B(,G5D29,4=9E'!AC*<65*!,A51-&43*5)(@HC"H%GF%+D>D?5/*!G&57B&2238;10("6((%$D+./.!9@306
@r799
ATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGNAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTT
+
9<>@$F2!0A1&;=@>6<16E$#C*CH,@C;B+")"0-9H@H@@>;)*G$->0GG1;G%7(9##<G5G"-+3"$4+D8>B"*:2="FG/#E#'B+1(-0(4=$2"3-6HC<(34A+=C12)&A@-7"-493*:&D:-HG6-E*4<CC.D<FF,7/C/6A75.>&G:.0C&=2()H(-6-8A*29D4*=6C1G8.*)8(6)@>B(%G$!-5
@r800
TATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTANGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCT
+
D(.9H69+2(E(A:&5FFC!$@02("16@#H4:$;98=C+;9,7G:#/1C"D17**466C!8*(44),>,09:F"#.A
@r801
CGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGNCGTTGCTGTCTTNGCCGCACTTGCGNTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGT
+
FEB?/7F1&!7A=,A35C>A8:+A;3&+%*!0E+9:0)#H00#6BAA,B(1/&H>E>/>/"$>F-0A$3#-C2*6"HGH.5,D*99$C6A>A?D"6##H$8EFCF>!HFF3CHB,/CC1E/0&C$:BC2
@r802
ATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGT
+
H$1&CB%=FF:E0&4E##;1*<9D7;B;>H)&E40E9F?%(GF
@r803
TGANCAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGNAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTNGATGAC
+
@3$="644B./FA!GE/(>;47(8=*0@=/&@'8AE,10?')H=%BG"???(7<?/)14DA8.B,#H0:@<!B;#@/.0%%6&821>B
@r804
TAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATNAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTTATCAGCCTCTCTCTGAGGGTGAAATAATCCCATTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGTCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGTAACATCATC
+
A95,$<71"2'G@4#*D*E??B46,1=75('53=49F-+;<,H>'/.9>8G2*7+=G3)&8#DA<)EG"-:,:H;:B9H=1#32AA$>;DG3E903A,"4.B076:*!>3,')4E:<<*+EH!)0!4B<$0;B%C/>8@4GB@B"%CA;$G%/+;,E&$-!.*23=))##:D.3;H1C&!#:$4)/"*5H4C*2G5+A'0A03H.0AFF:H0<6D=%-1!=A(<<'C21'4B=;"?D*=,=)#,384
@r805
NGTTTNNTCNATGCNNCTTTTTCCGCTTTTTCGCGTTCTT
+
$'*")!"#'''*%($$+%))&!$&$'#$!+#%!"&(&'*+
@r806
AGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGC
+
D;9CF6A3/:ECGC:)9A'??-+8@*94#,%E'$69>39?<
@r807
CCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACAC
+
%=.EC?@/(<21?/:B>E?$4GC@626C/8/=F86<,7E@<-00!+G6+)0E<&A-4H*$:71B-%9B:#;(:)7/3!">?
@r808
TCCNGANTTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACA
+
(&*%($*+*&+!&*+()*$"&(%"*!**)+%"(!"$!!")%"#&)"#+*!!&"$)()(&")*$&&
@r809
TCNGAGGNGCNAANCNNNGNNAGCNNANNTNGNANTNGNTNANAA
+
"$!"#"###!#"!###"#"!"$$$!!"!"""$"$!###!#!"!"$
@r810
CCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTNGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCT
+
6G!7A<71="(+&-H6B#,%8F">2;A1E?>3AA30E94*G*&-'&/3B:+=(,>(@DF1FC84#;H%BB$+3E0B=EF7>/B-HC05C*-+!B91/H+@452)D?<A2:/"=%2#<;%(>:/6/22<8&063!F0@"8***17&59,"%1#@8*'!3(3$ACEB2F6(3E@C'#7"35'
@r811
GCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGG
+
$B1F;!>)C.+-&(8@2?@;?7%?)92=27&$*%?:F(2A43(1>?D;B#@(D5/'H1B!?=0A'@5!%.38BC9/H?","2H336#7203;'1;=(51?2'A?6+
@r812
CCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCA
+
2C/-A7#;+00):'3:+-2;?7!A*0E578HAEDG828DH@C<C6!='8.C!0$.">"A/:A<!9>54>#61.&B5?A2"%"F?'36(1A$")>0%?:!7>&@(AF#7*::9%$1;!/9;;4@:1#8*-=;"BA7B&$CDH'G3G2G-;D*2%G&66/1E:@#G3+=C:BD.>737".<&.-@>-"2*D-88$'3F1#C=D09-=@$92(A/'HB(2HGD+:.??0>6)A4"6+"E*D!B3,.@*:)3>"0&
@r813
NTGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATNCAAAATAGACGAAAGAGTTAGCTGATGCTAAAGNT
+
!D'G"+A&#E+DH;A*%1<<EG,E$<,;2%%/6F@75@#6-2:F>C(D6=+-2.(@!,.%6;BH01A:7-(>>$C!30;C?8D/:9;+F)/59E2#:1!7@$DE,B4,*E=G/
@r814
AANNGGGCTATTCTCACCGNCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAATCAGT
+
'(!"(!)$"#+'!+$'+&##+"%"'!('"*$++()$(!*&''*)')*&''$+!(#+"($+#+'!+%!%#$)''##&)&*)**(&)'!+
@r815
CAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATA
+
/097?G278*/<0D$2536?>!()039#<!=DAD4)H,!"@*BHHC=!1$,+F$
@r816
CTTTCTCCGTGGTGAAGGGATAGCTCTACACGGAAAAAGAGACGCAGAAACAGCGNATCAAACTTAAA
+
6+D&?1C:+3/<!##0791&D(H;3E+&;>&A$/:60-"8%?'-C?.;7?A"150523>#"<,FF1!2
@r817
NGCACTTGGCGACAAGGTTACGTATCAGGAGNGCCTGAACGCGCTGGCGCAGCAGGCG
+
)A9!0%3=C>-3DA;?(:1%,>G?%$CG28GD142<H-3'8ACC!+>EF;9+)=5+9$
@r818
CTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCC
+
DD>GG9H-G-3=/'B8+:;5("-;%(!?A?=2<(+FF)-(?-;1;&<DB.20?(,(!*H,"$$"1:2(C
@r819
ACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTNATCNGCGGCCGGCGTAATTCCGCATCAGTAAGCGCA
+
?"=5$AED++,?)9F%3"D/6<1=<-&8D5FCFF&6;)A)H<&:"&!5)D!F7&=<-9<&0">@%?(4,#)7C9&*E+*"8%@7B$A((9.C
@r820
TGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGT
+
1*CD:48BC21=(56+/(>2*@=*19(0G)?F3&*-,%'A<8"D<>*F1''@,1
@r821
CACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATNGGCANCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGGATGGTGGAAGCAACAACCATTCGATTTGCNAATACCG
+
F:538G3D(819?3;?.9?H56+4G?*0)#3>50.-+/)%9;<+CDHA8F,<8.=1!:4/.94*;(.7(!=>9FC%%CAG/C:2B+>3E14&2%/FG:9B=C48=*9'(6F7A!H#&#4*/7B'@3G@3&&($H((:,?#6843!C3D$-'@-+F:-51G8$(<)E$D59&8;F&+H=?BC703
@r822
GCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGA
+
?6C7/6/B=H1",>D?."8!&=@,E=2%>!?.05C/"3821/B&>78).?E7>/C3("F.G1
@r823
GACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTC
+
=G?515?%#83$<:%=#?+CBB<>H<5<!+?"%7=.7>!F:G>"@F&13H@G'5&*#DH>8!A65
@r824
CAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGNGAAGCCCAGATA
+
*.<6A:">9%)CE:*##5-#5:C%)'<,C?'$'H/A&0&%92D0=?1+#!H'3>.:?$><H4&3$()%5=CH,E#/"$F>71@3/-!(7H@<8(1)8:'+51<,0E<H3?G,3-.(%8$/$.;82$0@6&63<89;8.2
@r825
AAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGC
+
">0@<5E7-*54D+%<!4B12,(/;'4-6DHA@HG/'5C*0>B&0+>9;,&26#<
@r826
CCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTT
+
&+'$!(*%*(%()$%+)*"!)$&""%(!%#%!")"!!"%*(#!"(*)%#)*&$%$(+)!*'*"%$"$&(#!%%)"*"%)!(*'!"""($"$!*"*"*(%'%(%$()'*+#$)'+&*#+
@r827
CAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCAC
+
C1*0F:A3BC<)"A?0A-!D"-?3.=F0$F$&!;**EE6HD%
@r828
TAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCC
+
+D9.:/G85;<>-=!':4,5*'8<'(*("..'<1%3B%0C:-4F56D..%><?3?1>56#2#918B45;
@r829
CGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTC
+
$+'!&#$(!+%!*!*#&#*%&*%"*)'!!%)$+'+!(#&#'+&"$+''&""!)
@r830
TGAGGACNCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGG
+
)E!-:@%"H3;-H=":#8+79?!E;@,5;)(/>)/$9"@8:<4FG0097B5G$5#:/1).A(&!E*;)&B2G-+1
@r831
GNNTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGANGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATG
+
""!%E1)&9>+DFD)9"199E)#-));?749A5<2%8G7+=HB%D"F?-+B46D,)A?4;D9<.3?&86=5>'./$3%=84H=#+DC;4#A<.6'::.>)0*'*C274;8%?CA*(58%4#*
@r832
GNGCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACC
+
)##)+'(")!'#)%"%!&!'+%!)"!($'*#*)+'(&+%+!("%"**+$!+&*&!"'&+%&'%+!$"#+()!$%+(*')!*#!%!%%&!*#(')&"$%(+*"$+*''%#$#()$&(%"+#!*)"$'##'&$*)*$'*&&'#!$
@r833
ATCCTNTCTTTGACANTCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTNTTCACCGGATGACGAAAACCAGAGAATGCCATCNCGGGTCNAGATCCNGGTCTTTTCGCAGATATAACGGGCANCCGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGNCACTATGCTCGCANAGATAAAACNCGC
+
'''%!+"#(*!$*!%**''+$$%#($*()*+&(+$&$'%(%#*'"*#%)"#!!'%'&$*%$+%)!"+)%!(("*'"+"&%')#%'+'%+)$+$$"('%)(&("!&#%)!"&"%$&%'*&&#$"(#+#'"&$!*+()&+(!++++*!+)!%&'&*+(("%%+!++%!#((+$%+%)#%%+%$##')&+$#*+*('$()#'++(%&""'*(")$(+)%("+$$))"&$
@r834
GGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCA
+
:E@1/EDF10=6<=/&3-8,8ED,H</8C(<0D(9D0>:G.D#/752"
@r835
NCAATAACGGCTATGNCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATC
+
%3#G7*&'!(822658231'8,HC6&"9E24E*(*G8H<@/25+-'<64<H82*'8/64(DD2$!-)3F")#9=>)$%
@r836
ATTAAGCGAATACCNGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTNTCTGTTCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATG
+
)+!)!%($%+&!*'!&#'+*"+#*%(*"("#*+$$#+")"%#&'!'*"#$+#"+!!'&%&&")##"&*$$)&)%''+#*!%#)%%%$+'"((''$+(&#($((&&!"!+(#!&)#!+*$)$('+"(#%("*!&$)%$'(&"((&$#
@r837
TGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGT
+
'5"*$C<#;84G/=G*C?77&F&1C=!G5%HE&=%4;%*A$9C-B,4"89D2+1*@;D3-7170=
@r838
CGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTG
+
B8)<H%'A0/=<F'(10).@0D,',4<*:/(36**0.0E%D'@937('!E9(D+?=H2:5C893
@r839
CAGAATCGTATGTGTAGAAAATTAAACAAACCNTAAACAA
+
:<?,&..'?+1H;7>0=.;8D8H=(C%0E5DB8?$B!853
@r840
CTTNCGTGNNNGCCATCAAACCACNTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGNAAAAACAACTTCAG
+
)"($#&*%!!$+%"*)+")'#''&&($#%+"+%*&%$#))(!&")"'$%#$)('*%'!+"#&$(!&!"##%*'!&)!'#(*')!(+%#('$""++*
@r841
GAACATGCGGGCCAATGCNCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAAC
+
9E5F;!*C,(=?E-:/.8CB;&#HE>G3$8/-4D9>#!HHGF7-%!A3E;-19/2>8G?659=3)5%?1'%">%F#+9,G7
@r842
NACNCTNTGTCNTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAGGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCTTCTGACACTACAGACTCAGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAGGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCNAATTCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACC
+
!$&"#%+)%#(#)$(+(()!$+!"&&(*+)!(&!'&*)'*&&'%)!&*+%$"#))"(('("+$(&"(!++!(!%")*!&&('()%$$##)(%'#")"'&!'(#(!)*'+"#$)*#)#(#+(+#(%+'$&*%&"$"$#*%)#()%%%(%+)!$!$%!#)&'#$''+"")$!$&#"$#+&)+)")!&!!'&'!$)("$*&'+)!*('"&"!(&)%%%**&*"%%'*!(%)(#"'**&%)%)$!)%%+#$)&#"*'$)(
@r843
CAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAACCCTGATTGCTGCCTTGACGTTTCCTGTCAC
+
34=0AD%8#1+E'&0C::7'1*!#86?#&2>H-C6<<'+920H$0="$9.3.=C,.GH@@($=3H@BC=$AF(0$+0'=+&)D,@/<G8+*
@r844
NTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGG
+
#;H4-2#!63;>H*%;A,(DH%.:'?=+>DE=(./@EE420)*0=")#H:F">A8,
@r845
CTCCTATGANCNGCNCGNNANNGNNTNTTCTGTNGNGAAACCGGATGCTGCAATTCAGNGCGGCAGAAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGNGTGGNTGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACTGCGACATGTGTGGGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCNNTAACGTGCT
+
'&%#'%&&$$""($!%$)!&#"*$"*"')*(*##((&+!%'&*)%!+'%"%$'"!#$'(!$#(*'))&%*#)"%($'$)%&)"%&!#"!)+!%#+#!(&)%*!!(!++#!))+%*%!+$&)!*#%"%$(&$*$&%&'")"##$!&!*$$$%*'+"*("$('#%""&#$$''))&%#%&))*&'+'!*+''+!#%$*$"$(#+&!*!%"(*$#*+#*!"&'(""*$'+)$$"+$**)((&$+*(%%*&+&!!#'%%+%#!"#!###()#*'#)&
@r846
AACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTANGTCGG
+
0B;<F81;+CB.=C&)?61%<)<*9/'G95779)H>F3/B*F>#F("*"*,"?GH)82CE%57+G>6
@r847
NACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAG
+
!+#**!'+'#&(")+'!"(''")%!%%$%*!!)%'%!(+"*'*((*
@r848
ATANNNTNNATGNGNNTNAANNGCANNTNTNGNNNNATNNCGNNGNCGGANNANNNNGNGCNNNNANTNA
+
#"$#"$"#""##"$"!$###"$!"#"!$#$$#$!"!$!$!$!###!#$"#"$!!$!!$#"!!"!"$"$!"
@r849
CAGAGGCGTNAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGCGCGCAGACCGCGT
+
+()!")%!$!!%$(!"#&&+#!')"$"$#!"("!*&$+&")&!%)""'++#)*$$'!))!&")&"&&+
@r850
TCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAAT
+
F4D@&"#6D$)5D3C8"9$=)9@,747<2$?9-12=D&4G?@G*(<'<E600+)#E5),D.*$8$'64"9''+
@r851
TACGAGATGTATTAAGCGGTTAGTATGCAGCCGTCANTTANAAGTGAGTATGAGTNCCCTG
+
3D*BE><1+&!B2"0A6>(H0B=+:2F$4#@H3F-H99A>"F68?=4*&++!!+@,9>$GH
@r852
CTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGT
+
H@6;!<,9+(G(<55&!@&$#(1HF<E>H7?.%H;+D(-/?F5<F48%DE06(FE(4E<)6,4&<<!/1:2,&+)2F
@r853
CTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTNCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCT
+
H,=?F.8(3"+-0;E1.H'<$(*1.&;2F*F;0D?>G)@F28+/EDEH"2>#E/?"!<B3H7>EFE:C!@89+"0@51"@'&16C$!")97080B4=1B48!*,>%B(-%DE/@#7/#%8)'-52.A25.7C7/;;3G9"B502?7#3#9!<4D##%+">"6G<1!2
@r854
ATNNATCNTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAG
+
)"%")#)+!*!"&)!)+!#&+&!%!++$)+$#('"$"*$!""+%''()!#&!$+#(+"$(!*&!)"!+#$)+'*****&!&$&&'$!(&&#*+'"$(&!%++(&)
@r855
GTCACACGTTAGCAGCATGATTGCCACGGCTGGCAACATNTTAACGGCATGATATTGACT
+
+#+*'(&*%+'!!)#(*!"!&)+!%*+')&#)$&!**&**!+(!$"*'*$%&&($$*'+$
@r856
ATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGA
+
B,F5B%.=#:?@C06'?6@?1$7,?;6(,@@3=1?--#B61*&;,;@&%//CA+AC:G-9A1GF)$G7G,
@r857
CAATCCCTCCTCATCTTTGCAGGCAAGTCCGATATTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCA
+
@&:@,/2E6B"'&=>A8@F*-450@!584B5&?#2*/H,;4=@"A)8%?(.<2,:7$BC@(:#F'?/EG9*5=;E7%<?HBC;$2(9>*A!82";47C*9F,G#G9A'&$)3#1/=0:,2%CFG@5EG/6=!/?$G*<AHH7>+G,D"A757)D(&B6-(>"H@"7?*58'!';F:!&(4:C,7@7D<1(<=,+'A4.G("4+-$86D@#/@D0!(@:B:*%!$@9/%&0'5,(2-2";*'!,BA6*$7B6*04=4@%=9E8F'1<DE8146@G'8B*4"50;8-1553>%'!3
@r858
GATGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACACTCGATGGTGTTACCAATTCATGGAAAAGNTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCA
+
))$+$#&%"))'&+%'%$"+''"&%+#('"&%($(*)%$'+"$!&$+%#%($&%!)%$*+)*%!!(*&+!%#!)#)$%&#$(!%#+#&'$#+"+()('!*%&##&)+*(($#$%!*
@r859
TTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAA
+
32<,=)7"CD-"8$9D"66;9-H<"456#2<G!2$-1!HG$??(1.91=D#/0#/6=/-68"#DH0<
@r860
CTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAANTATGTATCAGTGCAGCATTTGGGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGNCATAAAACTCTCCATTTTGATAGGTT
+
>E*(*,48CD+.9&C/C"4F@DGE4@94C,1H6!084AHC6;@,%F,0*>''D;><1?1HA%C:0>;89B,1#H/?B=0:40)"<@H)A&?::8D3G21!0,6$-BB+/A1FB39"*"4@'=H/#/E)2$!B?D&$-&7/A$1C47:=5B?'G
@r861
ACATAAACACCTTCGTGATGTCTGCNTGGAGACAAGACACCGGATCTGCACAACATTGATA
+
2:$H57"F>:7B4B/*9?B-7',D8/(">/G>&==:?$&!+(*#=,-06#.F:EA)>,A,,
@r862
GGCCATCGATGGNCTGAAAGAAGTTCAGGAAGCGGTGATGC
+
G0F'C6"$3"/:-E@4=-GE<%H8HCC"@=3'DBDB7?47H
@r863
CTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCAC
+
17>.9C7.>-2/#AF+3C0*04!89*9C$!#0/2:E&><HG+6?-'%"&C:
@r864
AGNCGTNGNCANGCNNNTCCCANNTTCNTNCNNNAANNGNNNNNNGNNG
+
""$""##$!##!#$!!!$!"#$"!!!$"$!"""$$#"#$$!"!###"##
@r865
TGTCATTGAACAAGTCCCATGTCGGCATGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCA
+
A7>5G9!'.6A58:.,<E:1)<DA0$"?;7H-=@A*BDE>F?9?81D.>>>94$=E?H+031$*>G0?GB6
@r866
ATCGCCAATAAAAGTGGCTATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGA
+
/==;*255++@:#:1()GF=#+/:C);:%63*5G<15GF66"EF32D'-;)25C5%#C9FE>%#'/?E+:H!FF9<#3=>)10(.,A2DD0>E
@r867
CCACTGAAAGAACAGCGGCTGGCTGAGGAGANAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTNGAGTTAANAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTNCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGA
+
(%,.'01?'88=H8C!0G*:G$$E=A"!0-$$<2GD"!),6H(.#4HE/.?10CB9<$7E;;1?D-77D=$AE$%'(?HA;H<"D#E7C.B-49<$88B6G;2"31<,D28?067="$:B59=<G4F=&=5$/<;H/&/.,/=:58!@;BD2A$,3B253B@@3*DC#@-=<42*785*!1H=84GC-1)FG#+)@/(,"B87>7#>A8$*H;H4==,#==-B<&2F/+14A$(GG+"#.8H8=;+8#HB.5#F%';.:.=,,'*%>'0@A60(&)!)1?$$BEB-"6B;;9GC7*);4-5E?C%5)$&'->G
@r868
TGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAANACACCATTACCGGTGAAGCCTTCGATCCGGTTGAG
+
;E<H)!&&!>6G--9?0C:6/18G'!("$5-;F55(#FA/(#</<6/:718CF%;?;')%5"C2!F!8A0'5;/:B24H7=)D==,27D3&-"5.(49%GD=H?C8@3(@C0*"@*
@r869
AGCATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGANTCGCCTAGAGA
+
2-)DG38<A#/)*%CFAG3%AAC"@G,D=2%0+2:)%E-""E,-3%2:9&HH7C?@A")B
@r870
CTGCTGTTGATATTTCTAAAGTCGGTTTTTGTTCTTCGTT
+
::3.6,&#68@<(H262'=F.,;))A3HH=++'<1A.=GB
@r871
TNTCGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATNTTGCGTACATTAAATCGGAGTTGAGGTGCCGCA
+
)#&"++'$'+''%)!'%$%)&'**&$("(+"!%'+$'#%%+)"&$()+"!"%)($*()$!+"!##$'(""##)&$)"()!)'&%&$!"$+%'%'+#'(+$('!'$'$%($")$'(++$()(#"$*&#$(""&)#!"**)!"&**#%(!#+(#
@r872
TCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTNTACCACACCCATTCCGCCCG
+
4*HF;,@9A-D8F&3@>&AA9;-H4#%@&2":>C*17>+!E$+1&&2"23=(+ED"*G/14F!3.+4F/)((9**3$:H(2+;#&349'>,BC16&8<8:C@)AF5;%<4#F:F@)@C.#3:,=#&0?/?#2='D&F4,$)?@/:442F!G@,8H1'F59@<4&?A76B.50(>-/$9+E7&6&E06C?
@r873
GGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGA
+
>$4#(!0$G&"'*B=F.(00@.1G?&BD23(G9<$E-%6,%*H"*,3A:8,!-!!#>2$.0C/?@7<$)*(?37';H5-;4/B%6(07
@r874
GTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCNTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGNCNGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTC
+
H'#G,3):.*)7(=AC@39!E#:=DEA)5F3>2;<&G0%<G*F==!2,F4607A>)B5@@F/0-6'@7DH.2;9&,1'?$E#3$%65E24,"$3&@>D@E"H8&=="'"&B;B)!;$A%7.H+(/29C>4>8'.<27EB9,*B=:B!?A$G&(CGA?*71"@$F@5"49$%!+&?%7(1A:8"2B!'.BG-%=!+-(5BCF%>;&27!5-.?A)$:5A
@r875
NTGACCGCAGTTNGCGCACGTTAAAGCTCGCTCGACGCTTGCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCT
+
$,GF7F$@:$;-$D((>18(3F!4$!HF:@(9>:;585$91&=G/;.8!DGCA)#G--$B/).$+$.A<E6<=F&(/.43&BC
@r876
TTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTT
+
$FD.&5!(#5?<2B*0392'6D61C&;F,0?1/5;G'78*&>'6.120<#>6-<%5;;=F/01/G?3.?C5
@r877
CGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATC
+
3#E29'0>;426,39"*2#'<48/$,$BC*C&E$,F*(41"-?+@7D8&
@r878
TCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCAGAAAAAAT
+
F(/*:2"7"%%779?:=,3@0#/H$*"123?>%F<F<.:2%G1""?D+!7;2&4+'
@r879
AGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTNCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATAT
+
#+&*&&%+*('%+*))!*&((#*(''!&)!%$"#"(&%$&%&&*)#*#'$")$)"%*!*("(+#&)#(*)"%$*)##!((#&+
@r880
CATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCATGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAA
+
=1?-1A6#H"""A$.>",,9D0/4+'*01)*6<@+=#?=<*F+0)7&BAC1?-<;)G./<#/<<D;E2C)65<HF=C??".7'HG*?E8*9>E6<F!D>'G86E&D.D-<6:5H'6D<H'@FGF*!%C56?E5"7$5=15"G"6->#;%'2D8;&BC<E70!0'2E@*-
@r881
GGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCNTTCTTTACCGCCGGAGCCACCCT
+
4-9/3;@A-?):.53,(!*GA'1=9#EA459G*C-2(?G9:F?#@C0)5$'),+FB=')7:+5&-1:#EA#8$(:#4/2>33F%C"63G"@494"78F23.'B,(H6:B("!<7=B3%G@B.<2CG"2@@>"@!C*.0=!#6;D>#&8;*?$
@r882
ANAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGC
+
'$'A0=("6%7.B=59-F0'67A+?,%<G7%2+(9BH8*+47*@077?7,?&-?"'3B9#3396(
@r883
ACGGCAANGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAANGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTC
+
.,0=&9EH:<"H=###D/:3!7">+#?+0!%B>.831(?<.*C9+C+3A=;*3A@=F/,!C0@1<41:9"E0)78(>DG"7C7
@r884
ATGCTCTTTCCGCTCTGCCAACACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACG
+
>>.!5F00."9"H5&/>6;"B>**:=+AE"84@43->=6CD#5EE6A>-7B"-B#A)+D8><
@r885
GATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGA
+
FE"'<%,3B'E4"*3-1;D'7<H%HH4,%<9;:8"6!5/?H,E?E(//>,(,+)1++$1+5C%9=166!A5#+(@$)F!"3)B(G:,*7;#*-?+%0D-%08)D'9ADGDA:A+&DE%C
@r886
CGAGTTCTAACTTGGCTTCATTGCACGGTTTGACAGNTNACTTTGTAATCTCGCTAAGTTGAGAATGACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGCAGAGCGCGT
+
0&,%+%26<59&#0A.1-3#1=#F!')3-A"21&%F*$F.ECH-)(4>AH00!FC"G.5-%D&6?+.GC&6-A,5;>=?8-DC?B1;.3+B+4:!"&02@!-.-%)**-G50#@1,1.GFG$A&B)##A3B'E'2#4=7FC'.-4++&F**FC./C74
@r887
TTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATC
+
@!!H.=??*'<6$FGG-!<AC2A'</9*1@?+?#9*6BG58>D+6,"E/&51!8#:%1
@r888
CTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGA
+
.8G19*,;>9,$)7*4H*5-*,77"?0=/E&0C%,EA07=2:<?.1)5B$(59(?:5G!&>E-,;B%5
@r889
NTGTCTGGAATGGTTTTTACTGAGAACGTCATGCGNCCTCACTTCNGC
+
#1.C6!'4:B*3G)3:858&9@D'%4+'@7C@;?15.36>/G!2'89#
@r890
TNCACGCTGGCGCGGAAAAGCCGCGCNCGCCGCCTTTACNATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGNTAT
+
?!8H)'9(C%3@F8;69:3+0B.:H;:=%*<*1AA,0G)*B9,FE-B;?,47>'4%C8?'65EG@F!&)<@&66$,8H$$G#*5.7+%'*4"F7(;)D/>:AC%%(<7<$,0CE$-<D48!&B=B?1B-;2F.'<0#+C*:?86C20<C
@r891
CAGGATGCGTGTAGGCGAACTTGCGGAGCTATTAGAGCTTATACAGGC
+
(A375.%>334:/D:@9,<<@5@,2)#A""):*D0/.BF44;$E5:*'
@r892
CCGATAACAACCGTATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGG
+
(G+2"?G7%FAA<G63H=E;0F!FB145:<1>!3-"'#?0))?5F)@0F570.->E#8GCGCG**/7925H?,&*7!#A)8@-!#02362!)<>.(E4A55#%B8?'.!B!+3?A+%2*/5*%)0@"+D&@!1G'B/:=<4E7/D;FF91+8)0/DC3&'G6+"#!?$G?#G<=)
@r893
ACCGTGCTGCGATCTTCTGCCATCGAGGGACGTCCCACTGACTTTCACCGTGCGGNTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCG
+
2&G5?A>,),76C)%"(F/8()/$HC&;$+*7:"(<>E998F)?2>1=9171/>3"$:;F"9'5<1;0*3852=F21='#%&7&(88B%+#1?7*!#2,8'=49,+(8-)92)A/@(($F6>
@r894
CGCGCCCGGCGGNTTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGNCACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCGCCGACGGTGCTGCCGTTG
+
'*+#+'&("*%*!('&(%))'**)#'%*+")($)*&*+*'%)+'#)#!&(*+'#!%*$&#*$+%$"+&()&*#"*"'"#((!""&(*!('")!+'+$++)*""$*"%**'
@r895
ACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCANAGGAATCAAGCNGAAGACACTCATAAATTACATGAGCAAAA
+
.)AA.D4!4,'.'>5%'$A4986($E:1DC(AG4#<=/*;1*@%=9H:E:5<0%-51:%4&7A>F.D<?4"'E)3*3:.4D:2
@r896
GTTCCGGCAAACGCGGTCCGTTTTTTCGTCTNNTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTC
+
78!?F=,.1<D+>=&;<>.(2"(3!1FB=D$BDBB?$,88C7(&0CC+4<BF<&<0$8#@'.,";C)C2+7'H@4E=7=333H9G@$"EHD+C@E0
@r897
GCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCANTAAAACCTATACNCGCCGGA
+
1/)22D'$+!5%2(?.H:*<,!?=%@+6>>"'"A"?C794*<.B2A.%2>':D7E@?%?G>9')H%77!>@)&3E)&--*>&'
@r898
AGGTATAGATATAGAGTCGGCATACNAATATTCCATGAANGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTNGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATA
+
?+:FB7&$F::40;.-2B>486'15G::!-F9E+3>);E6H@65.#?-10&:'GB=41>"3%9#<!H#74'@A3-7<=<E.8-#!,,2<C""F+'=.#,73@/3/&E??/;/E7$-1-*G?"(8%#7*5)><,-D4%>0%&.>.8$.1@H*#$$>55D-27<F!1.C!.D)-(&83?!?E
@r899
CCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTA
+
1<09@BB8EDD=9?E6<H@*9D9E>(B7A*=./"@%>77)*GC.>)D&@458E.?F7:?%
@r900
CCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCA
+
<*#GD'--"B5<>+G(<.>D2B@."6%:.A7B-&33@>A6/+E5;AE45)F2=.>92=4.H7C=HG<+*H*1-95%-7:=<D34-<"E)A<72?,!)-41,.,9G49%%18>
@r901
GTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACC
+
H.6/?&(C'C1:#!;-;8%3(,#624*"/)*%)4)&=9@;"G)#H,&-E6,:(70D1")-F%6;18!F:$;1+C>8F/E
@r902
NNNCTTGATAAATGCAAAGAGATTCTTGGCGGAGAANCCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTNACGAGTTNCGCAGTTTGTCTGCAAGACTCTATGNGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCNTAAGTCGGACA
+
(%&*&*%+%)$('%&+)*!(*!#+()*+(#$+")*'"))#&+$$!)'*%'!'##'($$''%"$"+%'$($+"($'*+))'+"*!"$%&))(%"'%**$*&)'#&&''*$%&&'%%()%!)&)#"&%(*''"%%##)&#)$!"%%(!%+""#'(&(+$)(")*%!)"'+)!")#(*&*'%%"%$($#+"$#!+)'"%%&%)+#!#&!#"&$)('!$*$"!!#''!$$$)#$*#&'%+!&
@r903
TTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGG
+
&6.*+#>?E-A;')CH%:5+2%;.8'F:"),*-5$"C/H"G0$*+'<)9A9DF/-;F?.D:>,.
@r904
AACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTC
+
-5?H.<.,#/#1@6?('9'1<6*'(':7&0<1'$9?3>>7!<0)A@9G>G#;6.F16E,*(
@r905
ACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTA
+
,C*GA!*GB-16A5+!,8&:/46,+D40:.9(D)+((%7./
@r906
NGCNNCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCATGGCAGATAACAT
+
%%*##&++$!'&$!"%&+"#%")%#'!&*#"+!#'*((*"$!&*)#'!%+'")"#&*('&'"+%++*%('%!&'""')*'&)!(!)!*'&&(#&$+'&*
@r907
ATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTC
+
++!$#$!"*+"!!(!(*!&))(%%&$&%%%&'+'$+*%&)*(!()"$("'##''""+#$$##!'&)$*"'*!"'!#*
@r908
CCATAAAACGGGCNTAANCCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCTTACAGGTTAGAAACCGTCAGCG
+
5@576&88F'C6G@F/&4(+3#?E)(8*%@.40/11A$.3-4BD:,A3@G4-<8@FC<G@#F/.7<-'H'CF,-''):GB;)7#0B>,E+56H5A.E$>A"2<2$=!'
@r909
TNAGGTCATCACGGGATCCCATGTGCGTNACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGAC
+
$$1%D/*-F,D&),0"E<86F/+G0>E;,5=+6D@&B-?A@D%AF-$@@?A?@E/>!80C9):'/E('-@CF7,%43.5>?4@>!4='<G,)%&.>H<4*5@H88!28%2<4674089<!.#!>25=5*H3)<,!6
@r910
CCATNAANNCCANANTNNCNCNNNCGNNNNNACTNNNGANTNNCNNNNNGCNGNTNNANCTNNNGTGTNANNNNCGA
+
"$#$"$#!##!!""!!$""#!#!"$"!!!$!"$$!!"!"!""!$"$$!#$#!"$#!$#$$$!!"""##!$#"!!"$#
@r911
ACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACA
+
+$!!&&#*#!%$!)*+$%"'%+###'%&*"'&%%(%+#%)'!%'#
@r912
AGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCNTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTNC
+
05(*!=C4?A5#7%6"((@D4..0*"B&7D<A++=&%E)41BC#:-;#'F%;08%!<6,$"D=)2:G:1H$&=*/%+:%':99>5FD;)DCB,;G5BCE(!'!%%
@r913
AGAGAGGGCANGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGNTTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTC
+
G#6;!3/1<BA+A#6=;>30;<C2&$*G673D'1B,65@F51*/(>/7,/=""5:CECG@@7(1C,99)5B<4D(G+)'2*7;$(=@??%#!+F93;6:G00F:/:=(4!#&G&5+&;%C?5G'?1*"<-87(B))
@r914
CAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTNCGTCAACGGCATCCANGAAAGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCNCAGAGCAAAANTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCTGAAGATATAGCTTCAGATAAGGGCTGTCGC
+
0'<*"70#C/+'8<E?;>A:<#=;2&47*2;5767=C%4A!@#<=/,)B+$"(1)/H2(:53D>C&+@A(;=DH*(9D0%;G)-50E?<)>EF+FG-:C,8E2B+!,;@F2:?C'4DG(&F**&3'21/-#107F!4B-,:'8)'A-@"D84@3.!28/>&@8D#$E(>@G1%G#>B*?B84E;,D:*":"HG2"*03'1-C=
@r915
AGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAA
+
,=81!B9GHFD4+?#5AC.HB)%E835?G?>E/@95E#)*D41
@r916
ACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATNGCAT
+
3BF-%@F15>%92'*E!@@1D;<2E:$HCHGF@16@@7*057'3&BD65-739=8((,:G*%%HH'@&C4@7>#@$7.:;E"A*:E7,,9@
@r917
CANAGNTNCGATCANCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAANAGACTCAATCAACAACTGTTTCAGCGACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGAC
+
&#"%(((!(%*&)(#+*(*$%'+&&&+%&*$%'$+%*")('('!+&(""*&$%''(&%#&+&$&!("$+(+"))#'+!$%$!+&)'"*((&+(($"*%($$!%*#'%#+"*))+$#&)+&%$$%)*)#%%))'#+((!*&+)+*
@r918
ATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGT
+
52D5*0%E>#<1$43!/:A<*9.=FD<)E+9('-9C'>%G6,0)4@4"B$&?1<F+(EB9ABD(G$0.(GA)E?3(1/
@r919
GTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGC
+
<'$.F.G<*"=#7'?:1FC>(B7F-%06)C(@3>.B.F/B@#2:
@r920
AGCGNNGTCGGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGC
+
("'*!**$'(+*&)"(')%$+%$(('%*)')#)$)#!)##)()""'!(&#(&!!!')#&
@r921
ATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTNAGCGTGAACGTCAGGATCACGTTTCCCNGACCCGCTGGCATGTC
+
0$4+G4:<7=--4!8E5!!E#*!@&:C2$0#3-"1:9@@*+3B76#H"1#.!9<#>+9281!27E54G+@D@+E>D&0G<@8476?@B=4;F'(*<343)/7:@""%
@r922
TAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCAACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTC
+
9;,EG'B$D;"%>DHA&CH="'<2$40#D1A.%B71*C"/;<78G7/FDBBE5()<9"-92<%8?H*(<:$(BB2+8<014>FH!(%E)?-+-';/'(!G2H57;(#'90:9@EFBC/91>E!B?+##5DA0%6@D:B'<%-+"EHH.C%C/>A3/:%8A.4=2>%:1#0@3+&84",4(?-#F"5C$26825,;(<H*>?6D!#;=/(#BH1*"(3;&6.":<?/)G4B/9FC)BA.G:/51/9$E$$*,!934
@r923
NNAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATG
+
)'H1'&"2E%>)CG83+CA',<18&6E?-7H1F-C4>FA<BF9,3*1HD.3%=;&(/@@@)$)?%8CH?""#5%%8:,2""!FC+*>.;<;64$9EH70-F=AD=!0@528$@5-,;;F01BCF!GG!
@r924
NNNATTANGCNNTGCGNNNNNNCNTCTNCNTNANTTACNT
+
##$#!#!#$!!#$"#"#"!$#$""!#$!$##!""##!"!$
@r925
NTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCG
+
$<#**,0=34A?D85!=67-,3>*H8.087>'2B?3:9&B7C)+806=@D@G7#7#72"9D2-
@r926
NATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCC
+
!<"1(&(&+:8)62600E#A;('A32->-6.CA'%A*!(<)2A%,/E-#-
@r927
CNNTTTNACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCGATCTGCTTTTCCGAGAACCAGAACT
+
")(#+)'$%*#*)!%*#"$!(!))#*)"+%$#+*(%**)&*+!(#$$!"'&%!'*'%+%%'&*'!*!$*!&*"#&+#*""&'(("&*)%'%$*#""%'%#$"$#)*+$"+'#+*(%$)(()+!)%!(&&)#%!&'!!)!'*+#%)$+'$
@r928
NGGCAATGCTCAANGGATACATAGACGAGNGCAAGGCGGCGTCAGCCAAGTTAATCAGATCANCACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACATCAAACCATGTCGCTGCCACTCGCGCAGCAAAATCANAGGTAAGGAGATCAATACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGNAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCG
+
%+*%!(*#&$'%'!%*#"+('#)(+(!!$%"+*%$()'##*((%+&+(&)(#""!)!*+#)*+(&')'!+'!'!(%*&!!#)&$"*%+$"$+$('+*(&'(%$)+(*)**(%%$$)&')*(&++!#)&#"""+##))*&$$*&&+#**")&%'!!$'+'"+##+)((&'*$+&)"%(++#&#%&%*&*#(%!)*#((*#'#!$%')+#('&"'+"&(+"#!&&!"&!++#+%'+'"$*(#*")!"%)%#$%!)&%'%&)'"%*()!)!$**'!$")&!!
@r929
TCCACACCCTGCTTGCTGAGNTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCAC
+
E2H,(@EGG9/D0<,%.!@"*E5,G5BD%;..88>'&5B6=3%+BF!2,:E)D5*!>4@CA@/-4%F!E94@./D:/(%(?D*%FH/'>"9DEDA&*7AD(.75()/*,1B"
@r930
NGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCAT
+
#6B1+=$16'/H78+&;3*5;(48<.FFA-<:?!.28@:%?;&
@r931
CAGAGAAGAAACGACGACGAGAGGAGNAGAAACAGAAAGA
+
)B.%,A4<:2E$G9;8&F#$56:A)H"'%B91?ED>/5,$
@r932
CATTATCCACGCCGGAGGCGGGGGTGGCTTCACGCACTGACTGACAGAC
+
@'H<G:<H!A)'$"27:"(0,-A#<>8D<789*$'1;>H(/D'F&C('7
@r933
TCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGCGNTGCGGCCAGAATGCGGCGGGCCG
+
H8)7-F&$@>.;-17?H*=!FA!?E3-9-.*=6#('7#4A!7H50A=5%&)'"C)9<"#D0#-?:"/-:&!4
@r934
GTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGACTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATNTCCCCTGCGTGAATATCTCC
+
"=;"<3&5GAB?$.<:G7F*.ACFH)HF)#91G*F.=%&H(?#!(E=1B(!9>3-*-93?,:&+4"4%6(/E@?7($(28?8>?*-*=@6!->%%DE4
@r935
TAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGNT
+
DG:89"(=:@2G9H'"/(.7:5H4<('0C?3D)+0&07&>$&"?ABCA"D1CF,H%.
@r936
AAACCGATCTCACTNTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTNACCTGCATCCAGAACCCATTGACNT
+
9,<131H(+C7G3A,2@!!5?;*7)."'!8D.:A:39H65+<7.!7*"3:*.?G+A5-3,51'H>)B)0?/1=3/1-5GG6;*.-
@r937
TTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCACTTATGGTGATCAGTCAACCACCAGGGAATAATCC
+
0E)2*?EH$0E:2;-E(2B56=491'#@#-B4!887&(DA*:AAG9G?@#0)7?C0F<$+136<%EA.$/8A7EF-&&5.!;:!1":/76)*1'(*E?
@r938
NTCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGANTTTTCACT
+
"G>G!A,G@7>);@>,(!*H.>&8(;(#2<F"6F$E7,)->0E>=2HE-:6>*<,7-2D./>=#:)@>#A?BH,229:6;'#*+0<=4<>CD17F&((>426@@73-/0:?;;;=5&:#?=@?'B2=8!>/$,HA9%,,2%(!FH+>F5$)7
@r939
ACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATATNTTTATGTCGAGCAAAGCAAAACAGGC
+
.4H::+<F"DA425<?#C%&E#9!FD;-?*FF((*G$07E;H;EF5>B4#F?:HA<:/<(@FEB<A-0G',=;+':<2AD7=C@*E>4B'*,9:$D#!'64D;96:=76-E$)E'-=/?<):=95*3!0&:"D/FDBB#:@(>+)>;-CH&@4HE-A;*,,3D75+2(>4?:!)GAHF<F@2&478'38"95>(&H7,H=8"F?A&0,'+82(:=B;"!+780'A1!?/F0?@AGG!/35C5H07;'7##=HA?154&!8./CE;'-,EH61H'=7
@r940
CCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAA
+
@&15$"-04C'@?/4"/D:#8*CCH!/4<3)7!1.G0*7A"'>38:C.@882<5(006
@r941
TGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTANGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTACGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTNANCT
+
B4A+."&"8G7<?5"4.8F:$/89(*&="/EH!F=*"1457%<4(-#)A$/%.+("1F(#4H18DH(E806#(.4D(%@+<96.%+6D3$"BDFD=5>4..DD!%<'EFGB9,3H4<>21!!#$"A=,533!@;<0(5-57)H"23E?8*?'CG,4>AG?F#(7*-GA>B!/!,?54#@:/*+!2A)5-!$.;D-?2"9EHA>*@!'4;@;A!F'E=;4H-%.#?H:0-4-3H.9,%9."!>''18+?B-3,B;&-.!59A?")C;?E'3&=D707/E4$53@H"8?H/-7":+A52(A:5/=-<.
@r942
CCATCGATTGTGCTGGAACTGCTGAATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGG
+
:;0#D8#.=8-??86G>77>?;5>?397=!?7#!!&2!<>@,1.-GH/3H&;.<379*.;A%G/A&A0!9=>7G@=CG+
@r943
GANGATNAAAGNAANTACANCTGCTTTATGGGCAAGAGCTTTAGC
+
*)%&)&()%!)#'#'%$%%'+#!")()&'(++'&+)#!"&'"(*)
@r944
TACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGNTGCGGTATATCGCTGCCGGGCTGGGTGTCTCNTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCAC
+
B,"4-)G08C*,(&0#;7=&+@1(EG@1.G#9-:GF>8;A')4,C5B0+3?!6;"?>)'=51!3"F=F=$0D%G+.CB&!0/!45@-='FB#CF4+(!&0D476)-(D76%?H)'A0=4
@r945
CCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTNCCGGGT
+
D+B,"3:*<EG'=-0%4;$(&/F7$.;&1#1?9(*-.'+B>B%C*
@r946
ATGTAAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGC
+
&+!(&)!'#$#*$#%!'+''()$*)))"!&)!)*)*&+#)"&%%('#&*&#$"''#%#%+"*%!%!*"$''!+*)*+!"#*#""%#((##'"%#%&'($#$+&+)&!'+!'&!!%$(*%#%&("!#(&!+*!!"')(%'&)*+%+'&+"+'%**'&&
@r947
NATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTT
+
#)=3&G+?:6B!;.G,9+:3G=A:4E+B5,",C'B<6-0A:
@r948
NTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCC
+
!=&B'3?@)+("7F5$:22A!5F<:0.;*/B-D06F.6C)
@r949
TCGAAGATGCCGANAACGCTTACGANCGNCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTANGA
+
#*'"$'&%&'&%%$#*!$#''(*#'%%)$((('&+$%!%)*%#&(%#!!!'+&+&'#')""'%"$!%!"(""#+*!#)+%%++#'#'&!'&$&!$%"")+##!#*()(%$")(#%)"$
@r950
CNGNNNGNTCANNTNCANNCGANNTANTTGGNNNACNAGNNNCNAGNTGTNNNGTANNNNNTNANNGNGNNNTGNNNNNNCGCNG
+
#"$#"$$#!#""$"#$!!$!$$!##$###$!"!!$!!#"!!$!#!$##$$"""""#!$!!"##"!$!$$"#$!#!#!$!""$"##
@r951
AGAACCCACCGGCGACNGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCC
+
E)8#9.GE6%#0F>/)B>&C1;("H<9H+*G9%5:E@6#-BE/:%>E1-/7
@r952
CTTCTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACNGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGNTTGCGGGTAGACAACCGAAGAATGCG
+
C=0*>+4--2""4DD7H7/6,10#4<;:E6H&;(9*?E9HB(2=9C>E6!,@E#AA)H'..2H50+>52D5!>@04G=15$E#(96>/=/G9=-,"(-?47+(E5;??C"7(;"/=%G7@=!(*:1*9/=;C)C:/D%E+4=7HE
@r953
TGGTTGCGTAACAAAGTGCGGTNCTGCTGGNATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGC
+
;9H>2A!A/+42+#G52(<1H5:>&(,+0*-C#5H$/%<G'270,(#81>>80/.%5='5;3;G79<,*1@BEE0+(0
@r954
GATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGT
+
+@AB.,@;E.4+A'#-H<(A-.1-=>/2057C444D>/?4?(A(%-@!/DCB@9.H:B2:0EE#129;+
@r955
AGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCANAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGC
+
-&#@3:'1/-D/9502349A83GEC@1AB@38<3763(0?8<#=!"-.?,->CH:8AH-.#'&7:-G>/)79@B@*<*7@F5+'+:3."'6*9D@,)%6*.DFDHEECE+6@&4!<G"H$(-.2E-?.3C*!:3+H0D
@r956
GGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACACCC
+
D$-87.%,9:;=$;25E5F=5.F-)))A)/(H2#,702#3#8(99AA43!6''+=>:
@r957
CGCCGGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCA
+
&'"+'(%+&)#!$*%&))'"!$'$&&#$&%*)!*%"*(#(&&)%#!&("%!!$$+(#)+%&'%+((#
@r958
NGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGTTTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTT
+
"A73*"=C=?6=3+5=D=)!?.'4;>)#=/H8D7-#%5%60*<H5?>EB?/&')(=:7G?5EF>$/<D-,8@D/-?,1&D>:(F,>"E;F%>6@891$:)0B%65F#3955:B=;'C3">89HH"3:5F6%$8%6$.#'=#5
@r959
ACGGCGGTCTGTGGCTCCGGNCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATA
+
4D+D%)2%F,0#:%BBH?2&71./-D<B%'629<,""G!-D$2?5*,#BC3H2=$/:/1#GDG)<)2(G=;DB*$1),*@.5FH*D<
@r960
TGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCC
+
<91<5F9&F&9<H9)2+2/,.2<+)='%,7&5".*+".A(+3E)D@GG)()<1277.+E>E*&;?G3!3903/B;7-9CG$,*<3$/DC%=D+E9.3(G2D9)/H:>C1:<G/5-B'8():/E(,4
@r961
AGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCANCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGNTG
+
9FB59+5,;.%"DE.197B+5$/.?%HG7,F1#5*G($A"+2<),%*:$9EH8-E8&:'7(4-;400H5'.#5=33%;6&'D+&C)*:'0
@r962
GCTNTCANCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGNTTTCGGATAACAGAANGGCCGGGAAATCCCCAGCCTCGCTTTGTAACGGAGTAGA
+
(&#!#&'$'!+)!!+"%"!#)%+*+"$+&%)($""&$)'')*%$+($)&')'&!'$"()&&"++$#('(!+!*))&"+!&++()&##$)+!!$!!(!%#)'#%*&'&&$%)!$
@r963
TGGTATTNCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCC
+
56%A',';G?<>7!DC54?F),(6.1$#=6=>*4H*E!/F&4H2H2&0,9HA%5)(=>.*;C,;$F2*4#
@r964
GCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTT
+
4<&H6/2$B,D;=%;-,$1.%?<770>'A:%B2(@'F5938E6%45+$&:-%.<BF*9:$*,C;F."1BE.4:%FF1&4A=.A?
@r965
ACTTTGTAATCTCGCTAAGTTGAGAATCGCCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAANCAGTGGA
+
D<"1C>732C"9)0=&!",&00+:"@DE,F(*:-G2&4A6.-6B:;B)>#F<!2/+6EFG$B(@%H<1,+0@&*18E%D58+BH44G7$B:!E49>,*'*A"E:6*9>@9H
@r966
NCGGAANGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCNGAGCCGACAGGCGC
+
&-C'=@F6B1;D5!.'*:<#0%98E!(%-.1$<EF>,16&-)B9@8"9D)='2<@8E/'H6
@r967
TCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAA
+
H%B")/12,?:#-.G1""E9H#<%H>1/0;#*-CD+.4@D@@@9G00&E?60
@r968
GGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCAT
+
/%;7+7#$E#6'>F$>4%A==FC>A1?)E(D+4":!H>48:D*$#/743BB&2'4>>H3*3.*-CFE=GE!:1E-'C3?/5H7?A*#4:!%((20!+=A<C23C@2FB@+7
@r969
TTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACANACGAAGAATTTCATACGTTAG
+
8D$A$'5D#2-/B*:5@6,6"E$+0>A@!&.6D??>D)*+;8A:ABG;)G&E0%@GG>3!908.*(:+E))00B<<(=*&4..C8!D*85E"0H#E2
@r970
GCAACGAGAAACTGGCTCAGNTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTGTCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGT
+
GE3>:>24<BGD87<3$+6+E>?H=B"+A;6@A9ED>,"#(,(!")&@4?7%&C//+(87H->3&0,4)8(6E(+";=03=8-E89'=4?@-+9?H5.(%G"4;-87D7+370B4H(@!>C5<"$'8#27=D>%B/&9.'%'-6C!63*!408"9H4-)936%6!G96=6!3
@r971
CTTCTTTGCCCTCNAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCANTAGAAATTGAAATCGNCCATGACGTAATGACAGAGGAAAAACTTCACCAGATTA
+
5G!(8)"?7'!@-?80&)6=-E5,39<A66(78$G"+*#B8F*CC=H<?A:A0>5"%/6$4-.B<*=$A0/.!A3,+:@+<F>/@@);!E6H3!4D;H3.3/@F49-.>A9*ED"1>7A13-$D9'692?5=,%0%&!B163"A3!&'G,A569;/
@r972
GGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACNACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCG
+
(D5"7+*ECE!F28G/)*(+6GC"68F>)#B:5G=7D43DG%1%>!8/*3-,A7120?F03H':+*,"!66C20,A&H8A:E855#!3=A6;;:#E>1)!A8-H:.,F.+5"C9&='B
@r973
CNCANCCGTTGTTCGGGTCACTCCAGTTCACCNCAACGGCATTATGGCGGTCNTTCAGGGCGCTGAAGCTGTAGCGGANCGCCGCGCCATCATCCGGCATCACCACATTACTGCNGTTATAGGTCCACGTCTTATGCGACGGTCGGTCCTGCACGA
+
$!$$"+"('((+()"()!&$&$*+%$*"**''((*!#!!(#(+#!+$'$#!"%()'"+!)+))!(*%$!#"'*(("++&(')')%(+(&()''''!!*&("%#!'*($''!*!)%*!+%""$**%&%!&))&+"*#()#*&"&(#*$$*(&$#!+"
@r974
TTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCCTTTGATTACGGNACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACNCGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGAT
+
<):G332>&8:214&2$-6D7433(1):>4)=E0$>$/,3!$60D%9<4$+>C3&@<<1A&B4E*.(*431(H.=(H%F2HE/5!2/1,?601'*!/,$3$3</#6;?<5H"4&6(;."-2!&*F-!<H.B<->C-!053=6),.?:FA$10!F$-$F5,"=<=2AE529F=(,7F&=*-E(@'A6D@F!)BF590-*HF8$4+=20:%+'/2%+@/3<=%2.A
@r975
AGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATT
+
8?*//63.;"'5!+#=F1765G#:.$3C,9&)*DEC=77/GA#*E!!92F$7,A,!,B+%21&+C)6"2?)*%)0D;)H)&G>;)7&;
@r976
CGAAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCT
+
FHCD4D?('+&+0F3)?22(*6'(0)4B?%''F&%+;-("?DB*'6G4C%G&$G:'*/C8.E0%2C?E.5E"7
@r977
NCGGTNTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTNAGACGTTGTGACGTT
+
"H4%=%B%<"8F/H>&1<3D3>*&!"9!A@:=A&-=EA*1,.&"55+H3.F"4C08CF9H0,.+0<D-3+"3<AG;$/7
@r978
AGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGG
+
8:AD./(CE3D/$;41):03#F3=B;7G2&@7,GFG3-G+>2<&/#E+?46
@r979
CATATTTATTGCTGTGTCGCCGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCC
+
6583>+;7&-B<1H43BFA5E?47-:C9@)G7C$+E$%?*G4,/02E3'F&)5&>FH:9<2C5;8/F-$DAH$'C39
@r980
CCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTGACCGCTT
+
+#"%"+*#&)%*(%*%%'&!!&%+$$$%+"%)(#$)"+("(*')$'&$")%%+%$*('""!'"
@r981
TGGGCGCAGATAGCACATGCAGACATAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAANTGCGGA
+
;'"F0,1!&?'"-1->HB$0#,$))42%)<('%,-0=2$6":'<-@!/$7><;>EHA(-@#HB,C:?(-85,.E'6%/;3%&)E#876HE#:G1"A?"%#4)
@r982
NGATTTAGTGCGCTTTCTACTCGTGATTTCGGTNTGCGATTCAGCGAGAGAAT
+
+G#,2F<B,H#?$@$D!*4H@5FE.3'/*C$?"G1593AEF9E/A0F1"3<=,
@r983
CTATCATCNCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGC
+
%!*(#++%%*!$!%$)(''%)!$"(*'&&!*(+(&#""#&'"#%'(+("&$%("+'+%#)#)!!
@r984
GTTGCTCAGTTGCAGCGTTCCGGCGATGAAGTCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCANACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACNGGACTGCGCGGGCATTCAAATCC
+
6.,5.,H7-;"&!E7/8H3-H5/)'"/!4)%#E2DDD98:C*@?#-.=8*>G>0??+9/%"78D9C(*$.*B!;CEC)6-/')&+66;'>1+43&A(?+F,H%)+-)&8+G>>9','*24*!=#+E%3;//A9D.BC(4#*!+5*9-&(9%<>2#1
@r985
NATGCCGACACCTTCTGCGCAAACATNTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCC
+
!+'$()*)#**(*)+""'%()!#!"''"%+""#!!$)'')%))%!#)%'*$)*(*%((+($$#
@r986
CAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTG
+
3=3"CH11.20<E:(/3F<9)F6*(78FBD:B9'"2"9;#&.!B**'1C
@r987
GCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGTATGCCTTTG
+
2E<G>2,$/4$G+.G1)15)1C(A$=D-CAG(@$+<B<6D=>)BC%4C,?
@r988
GCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGT
+
2/5/(7==)@)+3,=4A*1F2$$B:+'G"2)H:-147C(B3,86C)85E4C9C$5?&7>/G//F
@r989
CACAGATACCAGCAAATCCGAAGGCCNGACGGGCACACTGAATCATGGCTTTANGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTNNCGAG
+
($"<>6)A>+F.)=,HG'-1)=>>3>/.<,$)@3@2$<)BA1,GC'&=4"H:3E%9>GDA:A'H-<?;:6$H;B7*?&7/0:"8/%6$47.=/G;,;GA;'2F-/1+>3&FC%F
@r990
GGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAG
+
>>"6!6B83D-1$?4F;E-0'F)HG2BGE:)?6(/18!,2
@r991
ACAGAGTCTCATGTAACTGCGCCGTNAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGG
+
'=671<19:E)');-,"/&$F4&@&?(0'=-?"9,#2*.C==&,&6!7,=#(@'":@'G'H*#6E5##&"F%F>,H2>'C:E@&C4&.?E,1%!GE1'026D)<
@r992
NGGTGCTGGCGCGATGGGACACACCNAAGGTGGNGAAGGGCGTGAGTTTCCTGTTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCANCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTG
+
!%+'$''#)#"+$'&%*&%"!$)%#"#+#!&*%$!")$%%*!"'"$#*#($$%)($!&"+$'*!"+#!&(%#+%&#)%#+"!++$)!(')$''''%"+!#)+$'!&'"")*!%$#)%'+&$#*%&!'$'&(!($!$#*'&$*+
@r993
TCCCTTGCACAAAAGCTGGAATTGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCAAGGAATNCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTC
+
0>!08$6=*##8A"C466*@(<#:C"@19HF%9'%$@DC>1;&<E2@%'F4HH9$'#-%:!!8FE(@<2<D$:-DD7B?F29)E9-55F9+4C</&!"D"$'28%$#53G1@65H=:!:&C'35+$D>.?5/')C"%<2@=
@r994
GAGATAAACGGCAACTGCCGGAAAATCCGNCTCATCAAAAA
+
0GD&.C53<*E>&15E#FF6.>AE!45B'=H5':H:(/3B*
@r995
TNNTGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATT
+
)$!"+*&%$$+%#!)(#$%!"'"'"#+*$&+&&&$'!("(("&$($&#)#+($*&))%(*%++$"!&"(+('&(*+$)""((&!)+!+*"+"$$!!*(+&*'!$%'!")%$("#&#&$!((++%)")#*
@r996
NGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATGATAGGTTTCAGATTTGCTTCAATAAATTCTGA
+
#:%B"<8>A5C/&E,./*=*63)/:01%).A"(?4)41)'<*1H++="./>$HE=.")<;4/%DF-=!!C"!DB<!*H7@+/7?$E
@r997
ATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCT
+
"D-/<2!:A$/7)9H.,@91=0<F$G!86""H6G3D9:?5H%&
@r998
GCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGG
+
C6$6F</<<11A)(H?26<4%(,H15;'C+4A'FH#@CA76.>!$=(*(DB#C?.C:H!$/+G.=,%?>-$D#('2F(FH1H=4%6EB.19>DA:!@,D0&3201#0.#;FAHB1(GC2#$F:9*+:&(CH93?.,(0:
@r999
GTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAAT
+
C:*8547"*$>)%4EG*62/C.;H=0*>(9&9'E0+?77;D'>5@%%!<2>'D1?8&G(
@r1000
GCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGC
+
?>;(86BHA+"9=&HG=!C?..*<C(0&#0/++5>*(3.3H=:',+1EC?.85&*5>='9;2$::@@+5.*-39'4#0*:G(%015"1?021;6?2*@G,H3>$H&G!A?6;H=>/6%54;!B?/:83<>*;3"B5E7#
@r1001
GAGGCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCNAATGCGCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCG
+
(%#$('+!)(+"%#**'&%&$#'%+$#$*')(&#"+(#%$)#*$"('(%&#%)!*+$+(*&"*)%+')#"+*!"%'#!&("$#+#$++'*(%(($)+&+%*"&!$)!((*%*(##$&&')!+)+'!#"#&%%*(($)%)
@r1002
AAGACCTTTAATNTATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTC
+
EF-#H%"A00@C2#F)(/:6!5'2DC7=C/CE1'F4D@08"B$@?C!?6$A#C"9?$#9+GC9'&D4E!,?=2.9<@!4F7-@4%*/E;
@r1003
AGACTCCGCCGGAGGGATTTGNATCATCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACG
+
52+=CF87/0)B0%+'8776-&)63G3%,>#H8C,!G#CF"32H,/%$;FA6+:<)&E(8AC6:>+'E#$?
@r1004
AAAAGGCTATCAACTATCTGATGCAATTTGCANACAAGGTATCGGGGAAATACNGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCNCTNATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGA
+
2%+F5*D+H%B>;G)G9="&1B;=A929!*EB+$$("F%.@)@@@!2<E6>C!<F48=$,=-E.'F5B%ACG#&5,=E(/-B96.C9?-/.1>=1@4)>='<=1GA+1)2";A50+C)'3C778:'+@)?;#B35=E"@2;0.2;C/!8))%+)$5+?405
@r1005
TTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCG
+
-*GF98CD%25@:/D3,2#-2!$*@0?;BC-(4@+/F'2<'@#"=G;?!->1F1E"C<E*)(H!>:=5+
@r1006
CTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCC
+
48@9CH6G07?GG"*6EG!H:17DG,%2"C!<+8+&1&B8)<,FFA</()
@r1007
TNGCCAGTNTGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCNCGTATACAGACAANGGATAA
+
#!%('$()"#&+!+)()(%#$*'($"%#*'!))%$*'()$%)%&#!#+)"%%##'($)()*+$$'$&()#$%'!+##'(
@r1008
GNCAAAACTTGCTNNCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTNTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTT
+
!!&'''')&(#*(%"&&'+&'&&!$$"+*&$$")+(&&#(%$&&**"((*#)&!(!))$*$*$!'*"#%+#)'&"##(+))!$&'%)#%%#%'*$*&&*(*#"!$##(&&""!##''(+%(*'%"%#)%%!"%&!(#*+)('+&'++"($++"#'!$!!%&%+(#)*)&!"$)$)%(%&(#*(()"#"+!#%+#+(+$&)!##$#)+"'(
@r1009
CGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACNGGCGGTTATGTCG
+
<B1$923A:$D//G,;@-:"7>@-34#H/2.(?&*4$>=<*3%71B';4+%CDF0#-;62<!$@5B5;%0A5)F2EE)6$8.B3E.2<@;?)H?$E!@!A=@8=6
@r1010
TATTGAAGGGGAGNTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCAC
+
-//;.-<)?'7:B='!(>B!B1#2?>0AAG.7C>$(+AE.A.27&#(30C/$*(//+>'.?1'8$):3>/;"0A42%9#3//'6?!FG6(A(6%F6%1$CD
@r1011
ATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCC
+
-A>B57FHB;BEG"%'"2@3*E6?*%6(6%&FH@%:HE+/@'6!65&(2+:.29E';<!B-.=G9C%%,2B,<,46?,"(+!"%8>7:02EC3(-
@r1012
AGNTTNNTCGTNTGTTTCTACTGGTATTGGCACAAACCTGATTCCAAGTTGAGCAATGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTACTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGGGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAA
+
'%!*'#$)*)*((+$+%(!#"#*)*$+)+#$#!***&'!")'&)'*%&%#*&!%+!)$)$$)!!+(""%)+#%)+##$'()*%&'#+"*"'$+*+)#%'%+%"!++&"*"%'!(*&(+)!$#&%('+$(!&""$'$()'*+$("&*')&%!(++''**'*"$##+"%(*%)$"#+#("+'!+*%&+'&("'&!+$%#'%**(&#!&#)'+**#%$)%()&)'!*(%&"+)'&(*'$'++""&'#!%&*&)(%(&!"!#+*+#%++!")#+$)&')$'*%("%!*("('#'
@r1013
CCNTNCCNANTCCNNCTNGTGCTTGCGCCATCCCCANAGCAGCCATCACATCAGTACCGGAAAGAG
+
(%!(#(*!%!$'(&")##(+%'"$'#+!&*#+#'!"++")#!'()"""#%#"*)%!#'&$&&#)#!
@r1014
CGGNAGATTACGCAGCTTTGCTGTCACTCTTCTGCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCNGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTG
+
?<+)G)"FDG,=7A+E9/.0)!-=,/"%<1(6!A<+%8>7?2:.E$;:<*5*2F5*.&A(.,)@/.7G*7(@35/3=G6-@B!(;H8>0*1@'-)8339#/"&<!+(H=<>"B44%/,;.,:3*A/,>D/1"C42"<BE">E?+&01:A,(
@r1015
CGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGCTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGACGGCGACA
+
H<+@B9..;:&DFD=1;1-66&=1*&:8D2>(7>'-')4!&!+HEA//$1<,$(@!*02H$CC#/%5-(1#D"/$HA(?3(0@<"+03,EA%)'&
@r1016
GNGTNCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAA
+
%)**!$'&%%*#+)')$"$*'%($&+*)*'(!!$&&$&#'$'
@r1017
AAGCCGTTGCCGTCACTGCATANACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGNATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTNGGACNTTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCNGAGCCGTNATTTGTGCCACGCATNATCCCCCTGTTCGACAGCTCTNACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGG
+
+*(#%*!'!%**#&''%+$$*)(*!%)%"%)(!+'("#''&!)#$)(%+"&!$!&*$"###%'!)$#!'+$&#(((!&*&!+&*#)))&!$((#)&%'*+)&#$'$+(+%%"+#(!'(&*'+*("'&%!*&(!++)'*%))!($&!&$!&$"!)'!(!)*"&&")#+"$')(&'$+*)%#)(('())#"$*!&*)&('*+""!#+)(++#"(((&!#'%''$$!!#*%%&&!)!*"$'**)!!%""&''(&&!#&!*)(('&"!*%+)++!%'$&'(%+$+&"'()((#&$#$*()(*)(&(((!$$#$)**!%!(*%()+!'')#!#'#%)'*&"'!(&#'#'#"'"'#(%!&&+($$&$*(++!((!&&&!%')'$&&#*++"##"")!$$)!*%&$)#+)#'
@r1018
AGGTTTGATGACAAAAAANTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGT
+
E&'".)+1@D@C38B:66?9DB8<)"@<@?%'F*/(&)9%;0H=($@DB%9+)"BB!H=;?6#74;;3+AGFH<446F>843/D=7";:!?FF)H%4(1
@r1019
NCGTCTCNGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACANCACCGTGACACCGGATAT
+
"(C<<,1&%389F1<.7%C/)>AC;8!(F2'%8/@&E1<4=>#>%9#%!:(/(>&.B):;'&$+70%*;%)(##'FH/H,?0>.@
@r1020
NACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGG
+
(27GA@9+B!0A?B!8#E:C9;+?&$6E:7.E*A*<2H7B(EA,<2;,HH$!$=/<9")#$;;75(*;<#9;A%"80*.*&?B&=+(#*-D!,>17
@r1021
CCTGTTTTGNGGGATAGCAATCCCCCAATTTGANGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTC
+
@+@$59+#A9,4#&?0="=07D8.4:;F#5%=*!$"A8?B25G'>G"!"2:5H(AF4$-?(,$$*(7&+)
@r1022
NNGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTANCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGANGGTGTTGCTGAAT
+
!%E&)4FFD)1/"77?;)*<("#$?>8F3+;G8&/1'%1D#D*#A;%<D2$!"=>H,+E9=1FH8,3GH62>!D,HE<6-4*)G@/!1@3FEFAAAE;0.?/(39-50##/'<3C(683=6?%)A><CH<;/=0;?"#>D5?8767!&6,+-'8!H2(-F;(4<FG9<-2E.G,+#(#
@r1023
TACTCCGATNACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAG
+
%'+*)'*''+!+#!#%*$&"!!'"&"&$)+*+%$"&%'%+""$+&)#'###(!"%'''&%$("*)'"***!&)!$*'*((#!$#)*&"'!'!"%%(#)*+#$+#*$)*%'*)%)$+(!+("
@r1024
NNNTANTAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAA
+
#&!#&!++"&$#!%+)&(($!!%"(!"**!(!+$!*!%)$$(&$+"$+!!!*+&#''$+*&'+#+**%#$*#'*!%$'$"$'#(+'%)(+'$##+$)*+'+
@r1025
ACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAA
+
9?+.A$0D28<>%*@(&=%%$F&"0!7!3'>9&B;E/#E!CDGB-0.9)#E
@r1026
GNAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAA
+
+G$E?!225E"E>27=G/#+1*"*6C$*3'1<DB19?;#GHFED:9<?46B.!<."9DF%;H/-$!
@r1027
ATGTTTTATCTTACTGTCTTGGATGAGCATGGTGAAAAATGCGATNTCGNAAATGTTAAAATTNGTTTTGTAGGTCAAAAAGAAGAAGTAAGCAC
+
-+(&HF$,++'2<?BH5)!?"E3"*"<DG4>)9.."1$0?C:*2-8E2/+&'F;%?#>80+(8C./H>5,#5C5FG(1$!<@!=EA"81%0&49-
@r1028
TAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGG
+
>B1H;#.'(.C)>>1,1+EBD)+E48F?@5787/.61<F%:.#2#B32C.5H4?H,D4D#G-3A0,$HA"24C
@r1029
TGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATT
+
#7'G0>"?(&1!;2!-F!9@*05,&'!0F"2;9F4!"*D,$(&%4&7@;5D4<E&A2+%<3%3.9H+57&4.8042<>B5
@r1030
GGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGTCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATCACACAGACAGAATCAG
+
B$C;@=C20B?$BBGC:+4)6/$.@@&)#/"D(=8="F%D<&)>#&4/)#D'$AD;,33E33H.H?/A:*#).9%D@&C6&'@9*@@G?&9+0"E;9#3=<.(4H#@A?;F>4DC&CD,></!1--*3:GGG27%+"">G%2A4-;6>(H438;-@F,E)$6B
@r1031
ATGGTGTTATTCCCCATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATTTT
+
8HA<(:A9,>>*+*'%FG7'=*C<!'+@CHG<,?96"*90,7(5)7%;F.0C9(A2E1:6=(D'@G+@DG&6?-8&G?1H"E3G+)D5*#=)D9:6/'2B
@r1032
TGAGGATGCNCTTCGAACTCTTCAAATTCTTCTTCCATTTATCACCTTANGTAGTGGATTGCGGTAGTAAAGATTNTGCCTGTCTTTTAACCACATCAGGC
+
5-1::&+$G:+<HG*,B;H+/F>('=@=25A17834707B<"(AB5<9C5(HB@A9B:"8&=!4;>/!=&;8:!H59%%-;H/,9'8!;!D59&0)*;=5F
@r1033
AAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCG
+
9'8(17.2-#C6*'!,24=5ADA<$12<7E;F?D=()E33$4B>$'"G-7H$A%C1+9+<21E?E=E5@$8A*C;=%@(G/>15D)2:56>,&DC'",1*2,F?<:'?*C+"#E8/2E;H"!9>F$(2(-4D5+GB-0-?&*;'+4D9G),A,.4:#$>/D'%8'/1(-0>;&<<?0-==-2E?15'79!E#4</=87H%'4!D!;$8#<0'#H+H-.G$/'$<%#&%/%.1>?.5"!:)5G61%<!%1:B0E.BE6;4"69@=#GE#7@ED##3$%A9
@r1034
TTTANCACATTCACNTCACGGATGTAGTCGCTGCCCATCGCATTCATGATG
+
%&"&$'**$+&&+&)+"*')!$%$!#"!&("!$+#)("!'!(&)'+(%$$(
@r1035
GCCGCGAACCATTCAAAACTCGCGAAGGGAGAGAAATCACGGGGCCGTGGCA
+
7G)2999-;9)/:5-59;*1&:4-4!/<*&6<)1E(?6#+:46?8-HB@=B>
@r1036
CTGANTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCNCGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGC
+
<9H5=,B0-3H;HA('37&H?E?.9A>D9,)0'0!+?'=854D:%#A:A?!C4"&;",?A*9=+34>?*39C!0>6B7F,4%A,"8F,*1'EA<%)*7F>';H870,6A1:4@F-<#?D$;C"=<3>#C@.44H*DH</G!)=+(,+8**49&H*<@")'B1,/1322'4<89:(D+#*=3H@5"(0?A(E.*2AC?/G-'%1&G>$E@'#>4DF263@9+(H?>17!D42+"82=2A6.<30B,%C5H8<@&'")39#37/G#?-<8+C/9(>AD<%F$6H*<'4(&:("99753A+FB*:C5<;41F:./AD;4HF)*B8#?4!4!?-6#63HCF1E+4HE)9-15<D=B&"&&0#;1;"!.)1H0";2A
@r1037
AAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATC
+
$A88H"-7=!#(48B)33E8D2B3$7C>FE3,@6:*,C"/?36./5@C3<%79*6()D)&/!@E;1?@6-B"'"E:H797'!!5E:E
@r1038
ATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCNCCGGGCGTTTTTT
+
0:,313=%4%.=+3$+!")H@2%%8B!"G<G"-?GB%@+<8A?0<F0;-1D?/<45:;82DAD7*<;?
@r1039
TCAACACACCAAGCTCAANCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTC
+
E)+F$8>+$H-9C.A298(>!;"H9&-?%.#;,D8,02:G$:<>.:$*F#$6HB"D+%B5=#20;=;'")+'$
@r1040
AATNTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCNCATCAGCAGGACGCACTGACCACCATGAAG
+
$)%!GA<H?;:;)),209CAH@(B)1>;E2)/=E6:5&E<0>%E+,3HHB#%F><AF/=H9H?:?:+,A-*(??8411044G
@r1041
CGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCG
+
;!H(5$1#)&"D+?%H*$C"**'51G&A$8C6"/'!=/.@
@r1042
ACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTNATACCAGCCGTCGCTCAGTTTC
+
FH/?)ADH3%7;%7;"7$."<$&+(1D69E"D-$2'.>1""H5.B9#C@)C#++,+1!%,5('#)/@G!4#"<@
@r1043
NCAATAACGACGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTATGCCGCATTGNACTTTCGTCCCTGGCAGTNG
+
!$)'(*&&(!+"+'"((#!*()#$%$&"*$*)+%'#"*))#)+'"&(+*#'*+((%!(*+&"*(%"!!$(#!%)%*&&$"!+%"#$%!''(
@r1044
TTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGT
+
CH;$*%+#F6;'3&$D?>?('"<G%/6;@/?@"!1+??;*(>6>/A'F+H''!G%H5&C?1:*@$6-F+7DB--0%$:*1FF5064/#+9=."=#>3)//,5(=0F)$.1())F<"*612;%6385"4EH72@1=4D?)D>&E#>B-((+4'+.0;H,+:$9*4/FF
@r1045
CGGGCTTCCTNAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCNGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGA
+
$H>F:%/?E1C(>43"1?@H8GFD#-/AB.;B('.)E6;%1&D1(>@0@7@C!*;B'#,:*3C*C-@4!*&,8@(B!E+$;.="3.A)3+!-,&"//;1(7>0&9>?,@!+H++F+".:?+C#1C:*(129>%/A;*GE.<1#8:&>&)/=2CDD#131$@"(;H<&15F4@8+!'"HC(32GB%#A8>A38@%5#=#FD:BF'#64>>,).@0<.B/+1+D/"3#FE=='E
@r1046
GATAACCGTCCTTTAAAAAAGTCGTTACTGCAAGCTTGGCTGTATAGTCAACTAACNCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTT
+
1B-*CF51-8F/>5#">AE/04)C""/286(C%%4G?;@FB11?954*7)EGDC2G-&0(8!CH)11-!F)"ACH/C%6(,+?B)%"=(3!**967'
@r1047
NCCGNTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGNTGGCANACGTATACGGCGGAATATCTGCCGAATGCCGTG
+
*&&*#*$$+!("&!#*((+)'*('!*$+!$*+)+"!(+&*##$$%''$""*)'!)*(%)"%'$$$")"*$%'+!*+!+#*&&(*)(")#!%'"(&%")#)!"*&&%#&!$')('!+)$!%)(%%!
@r1048
CAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCATCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGNCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAA
+
+&($'%+(()&#+(!!!+"(+$"#"'")'+$('*+$'$+$+"!*$&("$)*"!""(#$")$+(()'()'*!#"%%%()(&+('!"!'"(%!)'*(&"(''%+"!$(++%)$)#%(#)##**#!)$'$!'")&%&!"'!$'!'!*&*+#*('*)+!)%%*'##!"(#&%'+(*!&*)#!'#$!'%"(!*()#+'$$"%!!+!#"*%'"'*"!!"&)""!)+$%%+!'
@r1049
CTGTCGCGTATCCATGGGGTGTGCTTCCTGATANGCGAGGCT
+
*)"%+$$$%)(*'$(!*&%)&$'$'%!!*+&*$"%''+)#&!
@r1050
ATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAA
+
H%4;$0-$E'<-"%->2E:,!-("#6@E%":48$9#/8/63.;?1B&,'@B(<#;AH:DF8GD+>6BF!1A!ED:4B,7#-09"9)=+)A?-C&D?03.64>B9;.GC?A-=C6=)'9*0$)A35;#HH5B'&$/?46/,7G9,/8/:'73*FA5!6)@.)D,5HB/5,E,"24@#=A>*1,GA44?75!=F/F0@G=C:3&+DC"9<!F9CH
@r1051
GTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTC
+
2/4:85>2C4H7=A#C;#5B$?>:'@,:B)9/@(;@CH18,1"77?
@r1052
CCATCACATCAGTACCGGAAAGAGAGTCTGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCNT
+
.=="(F7'<G(+37!,>CHFG!5?H-B7<,EF46+?HF.;;.#D0#;D5!C7),A+2*E1G6,@HC!,
@r1053
GAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTANATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATA
+
53HBH#=2$80HG4=5<92#7FC2H=:-"(A:G4)<#"74(+#*2>=.;8+/5.1+H='7/$69.A8()#D68D/!76;!,58=,A&&;>:/G7C*A3)@E(-E=..9)E*4?H#H5H=''H$41B@$@+.G>;#(?"E63':*7;6H.!GF41,HE@0#11!/20
@r1054
GGCGAAAATTGGCGAAGGTCCGGATGCTNAAGTGATGGCAGAGCGGAAAGAGCATTATT
+
08B&282:+G"H?A$(&>D5#$)'H$)3(H4GA(4)-%$6*+70FD3D5?/1+=!)F5E
@r1055
GAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTCTGGGACAGC
+
6,C<+@(@671@B7#6E&#!!6?7*'#05%:<3;B@62;"AC78B"H@B=$
@r1056
ATATGACACGCCGATCACCCGCACCATTACGTCTGNAAACATCGNCCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGGAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTNCGCATAATTACTCCTNATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATC
+
@3'9#A<!2>7%"$.%'=@>?@<5+@3)?(A550E*2:3C*0?,GF&'-0/)3*$C-.DB)'%>6.1@'08.>D9+!G0/1$A$?(/&@'&%?(4"(?1%GG:7@6E0>?18!9>F,F<G9*<%?<HC9(>$/3H)1HE.@&FA3E5;'-3E46C*$*CH;.&!24"@:)3'.D#245D='7<6&E&16GB@;=C"<9A*'+H7,?&6<38<GE;B:<&04=8-6%ED;*$6<F*8B,FGG:64;6H#B?#!#E>;EE'7=B"C%/F-?2>(D?1:5.;+75?9''+01!=54/,964%)'6?'=?@/@$5#''+*5/GF)548=$6F>*'3#;1A??0:#&D$?E#*0@<.8.G68;
@r1057
NGGCTTCNCGACCGTCCCNATNGGTCCGGCTGCTCTGAAG
+
&)"(!!&!'''#%$$$"$%&&!!*#+!&+"+++'))"'()
@r1058
TNCCGTCACCGCCAGTTAATCCGGAGAGTNAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTG
+
'"+)'+++($$+#+#)+$*%$(#!!'$&&'(("*(+%+&$+!(($)++#")%!&*&%$"#'!$"+&#$#$))$
@r1059
AGTTTCCAGCNGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGNCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCNACAAGCTCTGTCGCC
+
!@@03*8*&<D4!H0'C%/H6>''/!&48::#4AC6/@(%AB%H!&$?&0'==+=4,$F3/2C9*7C$;6',$/4*0A,&1<3=%$,0G8#%4$,,(40*>$E?7&9C982E&=#1:=E1+*B$)4":+&+$:!
@r1060
GCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCA
+
*>'>9),@0(G<+&-,-6!A<'BG0>,384<++A4!?%4%7,7!C%"599C=+=G"!C+2#?F<D"?B(DA&'H56##@3+!B2%
@r1061
CCACGNAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCNCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAANCGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTG
+
($++!)*$%(+'''*$'"'#$'$&(!%*$(%'%%))$$&"'%'$)&*#!)+!"+*#$!((!"%&+%!&!)")&)*%)#'++(+)*'))&&&%'++%&'#&(!*!&(!!+*+'+''&!&%!+%*+(&%*!%"#&*"$&(&')(!((!*)"#'*##"!*%'!#!%%!*%#*&#&'#&"!(#"$)#(
@r1062
GGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGNTGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCAT
+
,%F967(=CDB&75:+&BCEF-H8'#!34="+!'.%E-69?G2BFD4C5E14'&(HC<-<B'>15*)!"D"?/$C2,4G/5';2-7!*$>/-*&'939>@C24(4+:BE;<=/;'F!6;2=-58A-$,$4<'3E+F7.G00@;9)&'3"1783E?4<B>F4/EG?(<4#)D:?9%G)
@r1063
NNNTCNAANNNGNNNGTNANNNAANCNANNCNNNGNNNGNNNNNAANNANNGCTCGNTCNNNAGNNA
+
$!#"$"##"!"$#!#$$!#$!$#"!$"!"!#$$"$"#"$!$!###!$"$$$$$!##!$$$#!"#!!$
@r1064
CTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATT
+
4,1097$G3%0(//D@.!4%D,*<!6#+6A#)/0)"+C1/4B571%8@G
@r1065
ATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACAC
+
"$*+#)%*"*!''*%)'$)&+'(**(!*$'(!$&#(#+*')'&"!'
@r1066
ANGGCTCTACNTTNCGNCGNTNGCAACNNNGNNNCNCNNNNCNNNNNCACCNTAGNCCNACTNNNNNNCAAGNNGACTNNNGNGNNNACCCNCNNGNNNANTCGNCCNNATNNTTTANNNATGNCNCCGANNGTATNNAATNNTCCNGGAATAGNNANTGCGCNT
+
$!"#!$$"#!"$"!$!"!$!$!$#$!#"!!"!!"$!#"!"!$!###$##!#"$!"$!#"#"!!!!"#"#!"##!"""#!###!!#!#!##$"""##!$""!"""##$!!#"$!!"!#"!"!"$!$"###"!"$$$!#!$#$!$"$$!!#$"$!$!#"!"#$$#!"
@r1067
CACNANNATCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCG
+
*%("$$#"'+&"+!##%(#&$%'&'%(!++%&"$%$!#"&+*(+"(&%**$%($"%%'"#(%!)+"
@r1068
CACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGANGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCAC
+
1C39+G362=6.B*9A0+$1E>H+-'5DB>4*):)2!@.<$'7F.9"$)>D037,,E?@:G5(AF;/=D@3;*BGD3&AF=46-021;4.CAFF;F6;*.
@r1069
ATCGNNTATTTGTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCNGAAG
+
'&')&"()%()"("+$)(*#'&)'$)+#$$#(#"(")#!!)#'#'''($#$*+)$*&$')%'("+$)!%*$('!%+)$'&&*#+$+'"*(&%$"'(%!%&$!%(!+#$%*!#$*''!"+"+$
@r1070
ATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGT
+
=-56+F@"<)?$F=:>A/<.!=,!E&'B0#E6AG6D"11?7.)0B1A"
@r1071
CAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTNTTGAAG
+
BAD?/B7<BEDF7?E-*0=B65'6.=.-"'F')AC31<C77)>9%*0G6?=D18"@!,*:;!$H7-9*2A@41H/H1H009A9CEA/C>@3-@0D
@r1072
ATGTCCNCANCTCNAACNGGNCNCTTCTCTGCGGGAGNGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTAT
+
%%%%&$"')#%!&"($%""&(%!+)*!$&('(&!)"&%!$%%'$#*'(#%!$%&**)()%&!#$'("%"#+"$#*'$%)*&#&!'#*'
@r1073
AGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCC
+
+)')("+$(*(&%)#!!%*(!!&+(&!')&&*)!%((()%'(!!))*#+)*&!*#""'"!*&*$&)$
@r1074
NTGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACATTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGC
+
."9=E95:,3=/'A59;.>%>BC=@E05H.B5,B)-(><1:@'D5<.,F%?>;F7#D90?("2?,"$H5;BH=0?5/0D0+C?#>@%<G(4,E%&,#H58F%12D%=+6:(:4'CC.;CF*GC%7.CG"?(0!6551D9E8*$'60E28$-&@BA*595)(G#*#93B$=$9,/5"<)81:%=;/2:1"4FB8@3178,+,5D:#10'DFB,/@8)84(7<+-DA'->&;=::<HH1/09$'?:<?/=#!</8'.A)/5-71'=68240"@49>B'1/C<D@4)*):=7057,'+3>9F4=<@C/.<);;@+E=C5+'/<GBFG).%28/($'0"1-/&.D"(65,B-4$=1
@r1075
GGCTGCAGACGCCGCTGNAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGGACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGANTATGAAG
+
<3;C#1ED)6B%"+G0<2&@30:-:2%)&>A47CG-+A126(3/)79G%&,*,;)/2$;*"&(E4=A21(=3&77D!#,*.C=$#"1%0,H-.%1-00'B#"3:08?B?A!+E++6G31'+5<-7E
@r1076
ACCGTGCAAAATTATTATCACGAGTACGGTGGAAACNATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGG
+
$&+4(?(..41A4;3@F%6(C5"=3.;F"@0H-AFBG/36B6&(-'&:C?G'-;&B#B#.5G#"/,*<F>5A**)!7+6!$60@@">)B$*B;$;1<#=,9=%?ED97$%/
@r1077
TGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCAC
+
#++#&!&((%)('+&&#+#&$(*+'(!$++$&"'+"*#(''))*!)$#&'&%*!#&"')
@r1078
ANTTGCCGCTGCCCGTGCGGNACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGANAGACGGACGA
+
)&GF-CH&8C*ED(=G!B<:(<+G/8/E=!0H?:/(@4&%"?;/G1?/;'0+">,C6)$#''#/<'4-%#7.@18F
@r1079
AAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGNTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTT
+
)-:;;FB&G48/C?/((84-1!F/64B#G23>C607*D9""&+418&E"6!%%!/D>&F<-81F:.C9+B=74==H)+!@C060/$(%D!#?B/94!,"8:CGB50>*<)+)#:""88AH@D*!2A.#!F/)!":E<687<37&9:2+0"?%<*"A7E=8>,3D74;!96DHF4)3!=&.7B/;!')<3#:5B%;#!*@+42,+C+
@r1080
TTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCANACAACTTGTNTTACATTGACAGTTAAGCA
+
A!',<>->+494B3:0:<FB04=F6C)C&(C"9!(=>#?"!,E5:D@:C!''8%82<3770B!C6'"G5F#BA'1:&$,!H*EGB1,1/561C8E1&B1F8G!5;B#0--D03+6>E/92(/+'&4-+C1&F/0H(2@8&6!94G;51'G3)=##-/*5D@G7)36#0%')-9*H?0E*.E;6&D%*)/#53DDG$-8)"0;
@r1081
NATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTA
+
"80@)3+5!G*?81==10/&0;.D8=E+=H9+2E/#@*)#'!(8?0/.%-+>B7C+=(-"AC#C):0
@r1082
CCCCGCTGTTTTTGATNAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCTAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCT
+
&6,&%;H;>-E<3&>!H&30301((A!-#C;'&(#F!."'?)EA=7.@3,,D*/@H?1&)="(9,,D-$;)F&+>2/%(92/@,3D@4#.(#2H.G>-5?79E!"3*0A'5%+D8<783'5?7H%)%&(/
@r1083
GACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAG
+
9,AGH$6=@GG0G:@F?EFA@=E1&=7A&(4&38(3<2&H:31@<C"(7!AG%57<(G?<5%?/%)D)?
@r1084
TGACATTTGCCGTAGCGTACTGAAGAAGTACCGNGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGNT
+
&(2G/!0;A%+$'4>+=E(@.D!#;:#%(.;-;<22E9=4#@#.',&!!76*.??B4B58DFBA#BBDB%?%+G.*A.$+83,G%5-H&!4/@6.>@?<.@%=5!1?'D*">2,.00;<7(&>)-GD8"4?:?#72=<$5(3/F;E
@r1085
GACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCNGCGGGGATTGTTTANCGTGG
+
.+2-E9B0A%?'.0(.%2<&<$#-8)(8->,5?)":#.*C>+;,4"45H$1G*//#F)G@
@r1086
TGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTNACCATAACTACNGCGCCCGGCAGTGAAGCCCAGATATTGCTGCCACGGTCGATTG
+
+G=>E&A?%%22F,(=EGD##<763.5+'E6-F4=7<,(+,!<@4G2"6$+(/?304!%E1G"F<A+.8#5G-?7384#;6)6=&<5>H51"$1<
@r1087
TNCATAATAATGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGA
+
>1,C&E.3"A3"G4(8+C&1.D1#?5803(,,3HE+=F)H6&76G#?0(6(CG#
@r1088
GAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACA
+
4D)#1-=82?6$!F#;.?135>*&E%&*H:-*;C1B0/'2#&!C8'6+G?3,G*<0.FA8=5(:%)F0'D66CG*94"H=*8>$<;67;*A49A>,0.7*H5!>
@r1089
AGCCGATAGANAGCCACGGACNTTGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACGTACACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTC
+
#'++()*!)"*'**&"&%#*)")#%#)+!()++&)(!*+&#%(!)'($+%!)*%"&)+$*))(!'$+&"!%(+!(%$)%+"$'#!("&%&*$"$)&%$#"(&$&!#$)%&!)"'##)*(!&'))'$%"'!''+'$$+*)(
@r1090
TCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCG
+
6H")<H1'656##?:&+0,G"C/!=6/2>>(8CFD>E0D(:3:!:-7:0-A:7"!D+.68=:>3>>3$++-B&%47G(%*:%E
@r1091
TGCATAGACGTTGAGCGAAAACGCACGTTTACCATGANGATTCGGGAAGGTGTGGCNATGCNCGCCTTTNACGGTGAACTGTTCGTTCAGGCCACCGGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGANGGTGAGCCCGNAGCGCATCAGCAACCNGAA
+
+)*")'$($'!%!&"()(!"$"+*'!!$#)*%%)(!("&(!+*'%#'*$')"+"()$(!+(+%!'"&$)#+"&""&!'"#'$$%"'$)(#(&%"#**$#')%!*!('$"&($&$*&*'!!'(!%""*#'&+!$"&!*+*&)($+!#+!"+#)'"(#$'%!+"!&&*%)%&
@r1092
CGNAACGTCAGCGAGCTGGTTGATATGGTTTACTAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCNGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGN
+
"!%:%,D113+1.57D;EF,!F:"D>9%(0G#<2=09)@1;+:06&A-05C6<;E4BG(0C2>G4D/FCG=0H*:6*=4CC&0D>!.F:F=9C,+00$!<==%4D:!//"6=/GHG(6%>6.68F,E;9$*,DB-$+/6?58"
@r1093
TNNCAGNGNTTGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGGTGGCCTCTTTTTCCGGCACATGCTGGACGG
+
"!"()#"()#""+**'")('#(!((#%*)'"#*!)#$*"(*$%%)")&&$*#%')++'#!#'$(($!+'+)%*%+(!*'&#$$)+#*(%*"('!)'#*)#'$"+
@r1094
ATATTCTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAG
+
1*18";56:,$A'01=#2!')BHF8D?.<3<C6>B?E:?3?!>7/8H4?80.8H/$@!2?C)3&%GB0.)F::=D!*>+8>6*'>4C:954%+$;3F/*#>,D7$(8@,*$.3.!/=6A>1/&8)CH4
@r1095
TCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAG
+
4(4E46G2H.=:283)"=1;(F6(!B*"*.'!G!?52%;@"2,"$B$E4H!8A5G<;#"HF?G/A(18<>'"9G.?39/##"?"$#C1?'2?)//,H+B
@r1096
TATTATCATTTATTATGTATTAAAATTAGAGTTGTGGNTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTANAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGT
+
:&3H42D;*A'E!996F#1?,H%F"5/=.5@,"7="#('(A$97!!&@%DH&.'*,'4,!22/77/2E0%E>0E!?5$))/AG'#(0&F-(:%CCBAB0,B579'%)8H(49E@C;*":%8#
@r1097
ACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCC
+
<@5"85='&"/2+F20A3,=1D(54':B/!:<<B;>EF*@$"*6-=C@@1
@r1098
GTGCAACGTATTATCCCCCTGTTCGACAGCTCTCACATCGATNCCGGTACGCTGCAGGATAA
+
1@$D-(B,)?19'$B#->5A2":D',?*$.$8%B'="+F=?'2A4AC,8%H:/'81A25(:C
@r1099
ATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCGCC
+
3!7;,9-:&($3$@)40C5.<'B1@A=8/(3*.?B5)0/2F:E/(,",GEE.8&!=5+;#H$!FG+>/=E0H'":$%3.%14953*G0E+A77H@>F'8!G#+%$'83H4@-"-<=%#//+H'C=2F*$9,4<.9)9=+FD&<1<F0>AF';@0#,9%&@50<&%7'AF:9&#=;3<@2$
@r1100
TCCCGGCAAGGTTAGGAACAANATCCTGCTGCTTTAANGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTT
+
&;4HEB@<(60H/%9H!;"C&C2=(=6>H#:(78>G*2'2)/?6B$6/1-@-*$%E39*:"*,)73&@&6B2:0."C0)G:48*,C($BA"F'7C>B;0/-#&E")H34"4-;);ED"*81G7/87G"%'9*!2D9---F1"D#F(;)-7C(?H*D%.
@r1101
CGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAA
+
2E!$H;(,3%'86F8+G;.(E=@+?<<FE.>1C+@69:3$F95#?::$<@>5C#$+G69'B<<@>#!=858&?%%0:?F*'5;'A-9$>1E1)
@r1102
GCCCACGGAGGCAATTTCTCATGCTAAAAACGTGGTGTACCGGNTGT
+
@!2'!&?:0>GD>4+A;FFCF4B(/!61*58,#7/A#B/B"'&3>/.
@r1103
AACNNNCNCANNNTANCNNNNTCGCCNTNNCNANNANTNCCNTCTCNGNCNTCCNNNGNNGCNTAANGCNCNTGNTNNNTTNGCCTN
+
#$$"$$""$$!!#""$"!"$#"#!!""##!$#$$$$!$!"$$$!!##$!!$$"#"#!!$$!###!$!!"#$"#!##"#$"#!"!$!"
@r1104
TCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGANAATAGNGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTNCTGNTTTC
+
6:+&'?1</9!,;-6;"C3&2;6%=9D.<%A#E<+#0:*"#26"E11.%::2.A>=<'!/<-':85A-<<-&4=:&,C+<%:)<>$GAD-07,H'>H!&!)>(8(39%75
@r1105
CCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCTGCGNCAGGACAACGTANTCGATGTGTGATCTGAAAGTACTGATGAACGGTGCTGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGNTCTCCCGTANTGTTGACATNCCACCGGGTCGGGGAAACGTGATCCTGACGTTCACGCNTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATN
+
1H01/4DA#2HG0)9H!=A0(*20*!'@GG<"&7-=*H-1!=H:CH,/;@F46=>4%@&:"6.9D*C0>H0<70&;5C=780'=:DH9C(?!8/#C65C9*56#?#2"C.8-#9@(">G27#!@,+>31,34)0E5")4>,&:9>.>72>2>9*0%AF')H5.178@)-B',?D!*4</#0G&-/C<)D=>(41+22'4("/;%1H@@:6!A,@<!868?#;./5<6.?G//8(;GBH%;0*5$6F80FG6'F+07=5G8)?$573#-F!.>8)9"3<-=./15><E28/:)F-)@;8CAB8'HEG1H(H&
@r1106
GTTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGA
+
C??21$H=11/@A87!<*2?7;'C!5$F'%F%CB*D!:#!4!<7!."D':+%@6(.2"8D0544??:1"E+%3@0C59)=5
@r1107
ACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCT
+
E%.''809F0=29E-%1#.7*0<.'/-:4+)E"%F2#<.<11""AE*'*1?C/'8?@(=2#-%7+0B=1$1C#H@*0,A,#"1/":4HF-"%&*/
@r1108
TCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGC
+
6@;2,8H:6'./?=&9"5;)71"&@7HF4!/>A;EF;<&FD-
@r1109
AGGNNGANNAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGTGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTT
+
('##))!$!+#$($'+$'""#(!$*(%*+(&&"%*&)!*$%#(#$*)"+'%%&%*#+"!)'(+'*)#*'$&)'('%&$(+!#&%%!+($#!)&)+&#"#%"%%"&##'"#('+(&*&&$&%%%&)!
@r1110
GACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAA
+
'/AC8<%@2G6H4/B=:(@1>91-:?<H9F&;G7(7*&>C<F?7@6=::E@0$.:#$H*=!9;)#?+"2.0*+@;22B<,!C/:!>:?:,<237A.C@@/4)<)@/6!H?"%$00C<'#>66?&-E1+*2"?=:(%!29@H7:9-E3DG'*
@r1111
GATACGGGAAAACGTAAAACCTTCGTAAACANCACGCTCGGTGAGACGTCGGAGGCGAAAAGTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGNTGGNCCGCTACGAAATGC
+
+'#$'*+('+$##""(!)+#!"*$&"#*%"()'&)*&+&%(&%#!!*%"&%#&"))#!$(&+#)(##+#%($((*%&*(*)*+()#'+#(+'&+!$%#!+$(((#*((#*#%*$)"&$$&'#!!$&$(!%)$+)(")+$$$!!)$#)%'"!)%!&)*("%!"#'!(*+!$&%%"&"$#'+)""+
@r1112
ATATGGTGCAGCAGCTCGCCGTCGCCGCAGTATATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACA
+
#$++*!#%!"&%!)!!)(+#''""!"%'&!(%$"#'(%!!**'+#!&$'!++"*#**)#+)$+'##(&+$+""%'%+''*"+'&()!#!'')$('!*'"&(*#*'&*'##)!+&)!%#
@r1113
CCGCANNNNNCCGGTATNNCNGANANNTGNCTTCTCTTGATTTCAAA
+
)#"'*(!"("$'%&(%%&$##)$$#!&($%"+#"&$%%(!$('+')"
@r1114
NTNNTGAANAAGNCNCTTTCNTNACAACNAANTNNNNNNTGNNATNNNNNGNNNAAGGNNNCACNCANAANGGCTANGGNNCNNNNTNNANANNCNGACGNGGNNGANGANANANNAGNGNNNCAGNTANNNANNTAAGTNCNNNGNNTTNGATANNNANGNGTTCCTGTNANNN
+
#!$!"$#!!!$$!#"#!"#"$#!!$$$"!#"!$!!#!""$$$!#"!!#"##!#"$!""$!!"#"!#!$"!""#!$#!$$""#$#!$"!$#!$$#!"##"$"""$#"""$!"#$"$"$!#"#!"!"#$!$!##$!$"$$#!!#!"!""!!$$$#"$!#""$"$!!#$$$""$#$$#
@r1115
TTGCGTGTAATTGCGGAGANTTTGCGATGTACTTGAGACTTCA
+
5-E."363877/?/=,"41@3656.5"B760)#&D*$0"H03$
@r1116
NNANACNTNCACCTNTNATNAACNNCACGCTCGGTGAGACGTAGGAGGCGANAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACNGTGTGGCTTACCTGACCGCCGGTATCGACNCCCAGCTGGACNGCTACGAAATGCGCGTATGGGGAT
+
%"%$'(#''"*%$#%&#!(!&$%!!++%+$)+++%+*!&)"!%(*''&%)")!))!!'+')''((!**$%!%&#%)&*+$%"!"#+'($+$$$!$*'")$*&+)+*$!&'+#"*$*+&()#*!"&##"&+''"#'&+*"+##$*#+"($'*($'#($#')"&!*$&!%$'&)$*(*%#'(*$))%**#*
@r1117
GTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCNAATGGATGGTAGCGAAGG
+
50,3G?11D('4H/>4%,F0"#@$BC:8&3G!0'A<(7@<99"B22<3E;*1;$E"D(3&
@r1118
AAATCAAAGGCGCGGACACGTTCATCTTTGGTCANACGCCAGCAGTGAANCCA
+
+"$8%.+'<;@'2.9@")$#9,$$*1")*8)4,C'@<.',CB"8+1"H,%<;G
@r1119
ANNGNNNCCNNNGATGTGCAGGTTATGGTGATTAAGANACNGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGCTTTATTATAAAACAGTGAGAGGTGAACGATGCCTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGNAAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGNTACATTGCCGTCGTTGTCGGGCGGGNATACCNGTGTGAGTCATCTGAAAGGGATTAANGTGAAGTNCCGTTATGAGCTGACG
+
*""$%&#'$'"#+%#+%**+#!$*#&')&'+))$('&&*)$"$")$*'%!"%+*#'!*"$)+!#)"!!'$"'&#()'*+(%$&##)$!((""*)%"$(!)$*"'*$*!#&)'%*%(('%%$*$%!#$"&#%(!!&$("#"#'!*++%!#("'"'+)#$&")(&**&&(!%"')'+)))""#!)%"*$!((&)%"#!)($"%&('%#(#)#'"#%!'"##''&+%)&*("&#)*)(!%%!"&#*%#'+!*#"*'*(+$)+)+(*!(%"'"*$)*%+)('())*)))(&+'#'$*"%#%"+#*&#"$'"*(%"'+*)&*#("+!!*")%'
@r1120
CCGGGGGCTGACTGACCGGCAGGCAGAACNGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCC
+
6%572H:D:9,>%.E@!:;1CB,D,E3:<*C)?1E2$7@/@C0,9=!#;#1D*??.?.6*'7+;-%;#&%B7!B#
@r1121
GTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCNGGGTGACANGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCCTCCGTGGCTCCACGCCANAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTAT
+
+"#"#)!#*'+&%%"++$(!""+++%&'"(()$+#$"(%!$!')#)'$&##%'+##%#&('&*$*!(!!$)")"$**&"&)#&$"&*)*$"+!+"!%+($"'$(+(#($"&+++++&$&#((&*))#!($"%(&!*+#'($!+&&$+!!*"%)%"*)&#%((#!!&+#'"$()&+
@r1122
TNCGTGATCCNCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGA
+
!$*)*%#$((++(+"&(!!###"++)$#+&($&'!%"!#)&&)')!+$*'&#!+'$+#$*%$&('&%*&((('+
@r1123
ACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAANCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCT
+
>=58=2!=CG@&.%-GF1-8'1=7#12B-,C944%%0E)>E3F,A#$6:B4=?E%4216!%D:#"F+?.!6:%8E8-9!2/G!+!,08F>&F(/$?'*9G/;0<4
@r1124
NTCCNAGAGANTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCGGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTNTGGATACCACCACTTATNATCGCAGTCCGTTGATTCAGAGCTTTC
+
$$$(!)'(""%+%%('%'#"&("'$*(&!#%(#$()!'#(%)!(&*&%#*"$'('!$+"(+"%($))($++))&)%!%'!(!"+*$'$($&&)+!"$$&$#(')!&"*%*!$'$#"(&"+("*)$#&!$'+!))+%)!#)%)'(&'&)(!&"%%)"%)"((+$&()#+&#'(#%+"#)*%"%$!*"$#
@r1125
CCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGNAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTNAACCAGTAAAACAACTTCCTGTCATGGGCGG
+
G&@(+F53+92(?*9$.!8:#"7)<2@#/:.=#4*<C$;+>(C?+2G//20-(D13,'+2%(@H<'1F-?#/>C.&H>*A):F<&C:'#>A820#6H40!G"D(-!?4-/6A4(H74-0E&;/5!(-=9=CD*4#"(.%8(7H186$,35"0*HG!(74(2<4@;F92(&@2;01-1--3A1004+7$,B+E!E1&CB+@:E*5611$8(94<C>?EGE7;A;9))HG#E<%#A"A7>%=80-B(@5,FE5.+AH:
@r1126
TGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGC
+
2.>6F/);E/F@$+@BA-*!6%A'3!(2A#&872D/;2,132.E#,21%A,194C5B/40?C<>?(=#<D-46='93?39<"%7;
@r1127
ATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGG
+
8%(?2HD!2;,62)7@GDE-9@0A":(//?DH5*9.=C0(55$%!>?-2C?D2-)E&"=>(;/4?$B>8E355+6AF#$&2.6$>%AH5C?7(-5!;GE-2#ACDF#H3=?35/?';8&)>#(+(G9!CF0A2CF+-B!&(@/'F-76@!&+"2?"%032+A5H3D'7(>345:+)<%'2)!.6=3?1;5,?@7C.),>>;5$F=)((>A1#
@r1128
TCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTT
+
?H)94G.38430E,$&0E/.=6>$3&$E+;A@%A,E$=4,.+*-'/.@,B08.B-@5+53#"?
@r1129
GCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGGTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCA
+
H*-,3+C&B48<):)=GE/B"E(5C+&A54=775!"2@-7C5;1.68+C<3+;&#6@=.@;>F>/*$/!@<!?-%%*=HCA*.=-7#5B+'G38>&?!.B5?/;>FF&:&/"/.@"E)4<E$)+@;5:0;8>6C!+)3:A7.;!?&-:61-'12*H9;D>BAGF#/&F%;0<56*E&6%>:+GF:;*HDC.#3E0&;#G'-HE3ED/D<?0H/*G;&FDD6?5!+A#9
@r1130
CNGATCCAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTNTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATNGG
+
*#%%*"&$%((*'+)*#))%%$%(%("*$&!#($(*)&"('%"+)%!$()&!%%('+"!$(&!'#++$'"&)%)*+'#%#!)%&$$!'%(&+(++*%(++%"+)%($&'()#)"+$*$*&"'#+#%##'%''%($%)"*"+(&(()'
@r1131
TCCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCNACAAATTTTGGCTGCATCGACAGTTTTCTTCTGC
+
"!>3,3H1?")?5:<H3;FB.G<E+=>=,EF.H+02HH%$<)A#7,DC/?'*!8;58$+G!<&1;$D4%G:A6E)'(EC11''-:./B=3-<"
@r1132
NAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTNCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTC
+
*3<5,75367&?3!D(6E5H/0<*,?&)7.1$6>)9'D/53%53H2-EHF(&":'0>$D1C:50>-.<:19;F"4?8&.FD6+1..#2F8)EH)D@A(08H1=E*B%9G993C8>-C(2)B#%#*836C%FG7;;"?F&2E/5>*2+E84)7+A8?F/)(H"."?7B#A#$9!,%672A*>+B%/"$#3GH$G55!'?&'(!+@85!C2818/5?!6>-56.A"H(B&7!*:(+,BC<@49<35E6AF?885")8&.'!%'.#>3'6/(;98$2'A+5<"EC:7%*3"%9,*::2,'</&7@*.;(>GA@&'B#!5@9G(@(8!33E(GDDD'6*19=;D*=/%94A5G9);B8!+!/EE0&?%%6>79)2C%'$H
@r1133
CCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGAGCG
+
*%!ED<3?BD+E8GF>&C*69@(--3?5)A*2@+,2E(@9"2:/C#9C1G</,(HBE%4(8&*;HBF-$DD72=/6:@+#
@r1134
TCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATAT
+
7"08=4/)%8830-EA4)<'B&-/@@:F<$D76?0EF7*90FD$2G48G!$"E-");.A7-:*>1*$"!'>6,+'//C,-+"91&897;/"/)1#<+H(>7>57%-,+5$C33"13C!&G%88B$1#-F'#/4"0BEA*/:H9&44'H+3
@r1135
TNTNTANTTACANNGAAAANGNNATTGNCTTTATCTCAATA
+
#%*)&%$()%)"#%((&#&!#$!%$%')(&(+###$!))%*
@r1136
AGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGC
+
*C!?+29'3">%9""A9$:G5#G',<(7EG76:B&"E,H:B!7-;@;E5A!1#1;-$0
@r1137
AATTAATAGGCNTCACCGAAAATTCAGTATAATGTGCTATAGGAAGAAAATGATCTATATTTTNTGTCTGTCCTATATCACCNCAAAATGGACATTTTTCACCNGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTA
+
?D'!C@F7.$151<;7"88?F'',D<D(B5?#47,%%A#G($=$6/A=1*((:4GH-=*?4G6:F1>3#A42.GA6(1@.*).3'@#>>B/A$A)D(<7#,C?=,B8+9/"=H81/.'+EDB"-.'#*/*H%A'<<7G#8;-7:F;>42//$8C#CC+2551?G
@r1138
NCTGGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCNTCTCCAGAG
+
"&'"%+*)&*!!&#(#%$"&&)&!)"+&(+'("'*"#*(&*'#%#&+#(*+&+&%&"*"'$)+**)'$!#$%!+))(#'''#&&!$%)+)**%&$'*#$'"'%$!$)'$++
@r1139
GTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGNAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTT
+
2?08CC<$>+#;"?!"2;C5!H?+"-?">$3:@:.@$E=E+>.)3/97%3&$>!!"'?/&-@2;*+G).;':1$7>%!'"@B#FG:)<9AA>6HH/3#$G?-A&.#1>5#1
@r1140
ACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCNTGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAAGACTTTCTCCGTGGTGAAGGGATAGCTCTACACGGAAAAAGAGAC
+
H@E@978/'1&72=,421+).!(3>?F@'DA+7=44>5>,62(/G!?8('=2@.-H2,B0A4:D2$DD$G%/B71'34<%.=C.80$?@3#1&/G<C(@"3<0C+./%-<!">!7G08'92B#2!@?+31/>@HBH?$+E=B*D%B>)9+B!:,7)8D87#'0E=3228A4E*'41;8?".'H.6-"$/?A$*$-8BE@:3;(;@,D!7'=774:,43BH!5:)F,/7$%41(;$B*='<H:116E>>D;7#()+/BEDE(=+,F:6.::7EEG$92)0E*C(B"?=)D"6(>&>-D>:G#@GE/<*F'A27/8&%:7*:0.?/<3
@r1141
CATGGAAAGAGTTTGCCGAGGATGACAGCTGCTGCATTGACGTTGAGC
+
#6>,B,6#?=F+$61.2"@;$(E2*5-9GHE)E269!<#@H$-74)00
@r1142
GCAGCGCCATTGGCGGGNCTGTTGGTGGCGGCGCATCCGCGANAGGCGGTACANCCATTCAGNCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCNGCAAATATGAGCCAGCGGGGATTGTTTACNGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTG
+
?G!4&!GC/5:3!?D=&E8.A;D42818>/A2?;0)!4@0*G9,%!*/$33D?&?9BF<2?8C.-;68CFF2B5EDBE9)A9.G)"++'CF>F!CF*5+1C-%BB1F+5.B8#AE6G392.D)@!C:&B.GHH+9H6<>@F:C$>/-#/?%#B+>5%H=2A74><21E-@6*@<B"%5FH#!)&'CH>-4BH?1(00/7,-/1=(D0/8?<A46*,
@r1143
NGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTCCNATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATNTAAAATTAAAAGATTACTCCATNAGCAAATTGTCATTTAGCATGA
+
!A>@>$0766A+*38B5&&&%88!#+G?FCH&$-E>G?")">45+66?:B!4F/F.H<,6%%*37.;(<-)1;"5;D0A&;1G$5%8+")@#4=2B"=50?)+FC&;D6*'+!F*92?-DH8(*!736=&AD<@0+FHH/<*#'9381?%/%+@6(H@4B:DB"!GH-;#@G73%.-A)060F+H
@r1144
TAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACA
+
C.-?(/$..%7!F;2C1$'$C3$9<-'=2A%*H@5#,!,(12H8=A;+(>?@='9.=(B"C##AC$D2&=A04+04:;H78.37F#&D'-)?D<-*$:A-6698"A8/C*=<!$<:6$4=%B<?4!>21#=;(737*>.B)B&:D7'0.=.'26$8'75814DH59
@r1145
NANCANNCCTGCCTGAACATGAGAAAAAACAGGGTACTCAGACTCACTTCTAAGTGACGGCTGCATACTNACCGCT
+
!)!&"#!+&*%%)#&'"&($+)#"#)#%*$+*")(#""#*+)$($$&"%+#)'&&&((+#%($#&)!$#*%'%+&+
@r1146
CAANCTCNNNTAAANTAAGGNCTNNNTNATCGGCTACATCGGTAATGACTCGATTGGTTCGCTTATCATA
+
%&)"%)*!!"&#**'"*"(%#(""("$+&*'%&)#('$#$#'!*&$)+&(%)*#(!+)$')$"+(#"!"$
@r1147
CTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAG
+
-9B4>1:@-7'$><<B#4DA8>!!-E1C(5B660>-##CHA;+2E!>C8>,<B5#>!%3#/F*B0&<.#A)#1;D(G5#/?
@r1148
CGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAG
+
:&+1"$<64*0%%7==/-:9AB6B(170+,C%/>H5!C#B/+5.94<@1#0%7.3!5EC#("C6B)&'28H#?<*>**52:8%/4:*E
@r1149
TATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATNCGGCAAAACGTGCA
+
D>H<H+4-A6:<)>*&)35(C"8B7:!@91+>E!+7308<>#259F<E/*=E;A?C?9?4FFBE):;F;>;
@r1150
GGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATGGA
+
@-D7HF-9G?$/%;8%F$*:FA"->1:D#80)H5A??-H#,>*B-6/3?84=&'65-"7>&4*;85
@r1151
CACGGTAAGCAGAACACCTATTTCTNCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTNGTCGCTGATGCAAAATGTTTTATGTGAAACC
+
!<C"#7-31D7(;;A9%(/B@1DE)E'6"424D14.F352>DH?D"6$GC!&"43D<--=:1%&D9AGC1)!5!6A7B;?C02(,!8=1+!.'C*2E*C;9%B:E-'DH8+/%AHHD+2:>A55,?E=,>9DG6A;,5??!35.-<20A$7D#"*EF+=!8?@B*(BG'9$0D="*C79DC#9%,G#3=5D
@r1152
CTNGCNNNTGCGNACTGNCACGCAGACNTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCNGCGCGAAGACGATGTAAAAACGAT
+
$%%$"#)'%$*&!&)%$#!!'$&)'("#+'+*)$!($(*%$"'$$$#%"!+())&#!$'$%&"(&&'(%*'(!+)'*!"*#")'*&(*$*!&*#$$'"&*"*$*++
@r1153
TTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTNGTGAGTCGCTCATCATCGGGCTTTTTGG
+
G9?)($B71#>6B8:#"-2!,"?%A>8ED7;361=3%&('&=B:*-9;1FB"%-;4<26-8$:16#/,(),8:.=C/D*:$):*1D43C2(+-:+;#'04</0B#E23!)E2B,B*A-"763=629!#)$=
@r1154
TCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCCGCTCCGCCTGCCAGGTATCGCTGTCC
+
H<*8EB,-@E#2/81,)1B/-+;A@?'4(3)6-##G157>+*7?G;*583<1,C9B@FF@:-6/C?E?%2C*$7H*D.-.!/@.*5=
@r1155
TAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAA
+
%A$&E<.A-36$8HAG:H-(/%&@@C5<=5@/F(@F0(C</
@r1156
GTGNCTAAGACGTCGTGNGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGNGNTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGA
+
E2$?5#B!&,&A'B(B>74B#%/7+&=7!/&6<0.@;@B8(+&BE8?0&B0)."A)**5$/9<.2+"B,189585+1H65.8!4)A"$39B&(<*1B64?'(@G*@&"%A>HH40>E:+
@r1157
NGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCA
+
$,4:%5/#3?%4+G&G!"$=0!4<G@GA!$"'.#>-/+2?*7&?8.))E52%2?$6G&;@7DC@D713+17D,*,'<9*
@r1158
GGTGAAGGATACGGAAGCAGAAAAANTGCTCCGGATCCGGGAGGCGGANGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGC
+
+@7&9;E9(4-86$HC#!2@7,A?'B=%1C:G0$*9204C2@A*5?5D(C'&93E/57)!",F/B559;"61'=)#CF!2&;05&A/@82G':F,0D@
@r1159
GCCTCTNTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGG
+
H>DC?D0!DBA60..(+;.52B,?D(3&@;6BD-18(7(#H.02)6=7
@r1160
ACAGCCTNACTGCCCAGGAGGCACTCGCGNCGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCANCCGGACGCGGGC
+
5+,:*)/'=#6H',&*/!'5)'2:6*#$CD+&G-HC6:'E%D6."D2$F6$).>$H8&!&6-'/51D:@C/F%?.)!%$11*F;E?B,?=,9.1F+H;3-2-D$?)HF4H!)9D;!@:7?$/%(<?<"&>534)&5391#0A
@r1161
GANNNNCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCAC
+
$('#%$+(&))+(&+(+!)#'&%#%!)")'$*($!$%+!))%'**#&)&%#"&*!!"#$!"'%&!*%"&)#"
@r1162
AGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATCCATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTNACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCT
+
EH$5/+4!&=GF1'H"*.<!C1><1(5@*.0&!!,*H570ADE!()G"'8-3@8$#A;<:-6/'G?C%4<&C1;!:",=A!6&G0!!B.:,>%*:(8F2G5,!:8D1;5<B4AB@/EA>.")$6EB4?-8@-9/-D9/8DD>."$"#@"?'#->D/)7E:=82G9#9(F%"!4+9#45F&/(D13C$<+8DB?A??EC)?+#('8=;8:5./8,9.F#3B)&B&A<E)?//BC@?%H-4H6?#0-A9?*7>G1@B!-03$@:>F+7-H)<8(0*7=D(AD+AA332B@"?EH+2:3*42:0/@HG&AG@@CE*(69)@B231<H:>8D*E#5<""1*9%?D
@r1163
AGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCCGCAGGTAATCT
+
30?9=*.#"*:*7>258;@6/HH!.7?!)(20E$)@H@65#25!4)49)?C3;DA0,@5B@82/$GH9,(E;*414=H'"9$@"C;
@r1164
NTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAA
+
!D?!G4A?D==5,F1D,C/!/CB1,!AE@"D$;B??/,B(H
@r1165
GGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGNCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACAT
+
F8/?-:/;#2D"13?#:??%2*$!*((1'F8923>H,>'H#9+.5<H@(=35HC2'14-C-"(<"&A6B)$3&+1,5'<%$9E,60='$/@??*H-E@1;>?FG?=61$E7'8H!00#%A+G=/$F%%HG1".4>4&,BD!&7GHE#H>4,+.(:%
@r1166
ATCAAAGGTATAGTGATATCTTTTATGTTCATGGTTATTTGTAACCCATCGGAAAACTCC
+
09:D>!,<E+-@?F-,+;>!C7/16&!.H/8*C>@-40CE!%9DA?%0;BH*;E)'$#37
@r1167
CAGANGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGACTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTNGGCATGC
+
3)A949*;@E6.,1?,!G'E92:7(,)863':77C+"G529*C#!)>C!="2&F%&EH(7*.$,BD&'E%20<%/C3/;%D>%?G(+2$$=:D1-!,7:41B-+=&&(%-+DDBCH!H241(6&,H(3+"15E9:/C6%2#AH7"B%.$A6-#"F<):96FC&'
@r1168
TGTTGTAATCCGCNTGCAGGANTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGGGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCGAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTCACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCNGATGTCGTCTGCTT
+
-:<-"+=0"DG3F6%%*!8B2(>''.'7;/?75=,<?%:36*C#>4,-G47./'F/E;=;&('=!GE/*="@B>3>(G;?:5E75@H(3B!D2<9)'C*'"5!:5F6('0#/,.9&7!=E=H5-;B62-AB/@().E,56+H?0>);9FG4"@1#+"6AE/A0$G67H%4(88<$&64%)@F@)4-&(#F/=5)+)3B!<5</2C?-/DG<$=-,#5B*4'.D"-D;12*=#.,9:23+D4E*%)1/0H>#<;<A*=+$>?53-BA&9=*D'3-=1!0+-E5/?,A1=/:3'HA,31*A@.%;E?9%*G!<8
@r1169
TNTNTAGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTNAACTATATTGTGAGGCTGGCATAATGGCAT
+
""*"'%+'&&"+%+&'$(!!&!+!!*!+*!'&)((+&($(&"&$!##'$$(*((&*!**)"%"+(!"**%+"'*$$+%'&)!'$*(#'$%$$$"+"#&)+$%'#'&&+
@r1170
CAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCNGTAACCTGTCGGATCACCGGANAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTNTTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAANAACAGAACCCGCAGAA
+
E;G<*0C+:%A8-?-,>6=D)'3D'=&G)"<FF@"C27*:%>H&(4-770!%,?;;428:=BB+"@4C$E(%2/+%;.;9H%=G74?=//;<07D8C"9CF<CDG@G%8G:1::*!!=.*6H840":1AF)A4.=/5::'!F&0&."G##6&:1H?@C80$G@'%&.<%8-))(*"),/AFEC.0-&?5:>7+(5C#&E;3",%FB!)(E%9A=E?-3&>:;CA;08H2:C%$5&H;HH:@9,!,#7D@*!<FC%>H(1(C%%927B&@D&2.A7$D1#%8?@)9)@=B&)(/C;;)*+.?E4
@r1171
AATGAAGTTATCCNCGCTTCCCCGGATGTGGCGGACTTGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAANCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGC
+
@DA@3D1$$E4(A#2B5<AHF+6?(6DE4(.,E9EA@)(2><(D31G'*%,C=4<77-#&0-915:EC3@<:F-'E@@%"':2'->8!%>$;/AED,<?3//57&-GE-(F@2C#=2?/00GGE3+B0)1B.F0B,#G8B*<$9
@r1172
CCTGATACCGCGCAGGAGATGCTGATTAAGGCANAGGCTGCGTA
+
,,??B0#.,'2#&(B+B4/F.>ECA&$D"2B'74=:G>84H7#&
@r1173
TTCCGAAAGAGCTGGGCTATGCNCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCG
+
>@+67.+)&?!6FB%H12:23?/:4@.>,;.!H!73AE2#8D-B0#2.9?+'9.*';1(4."470D>#<#*,/1@*0%%4B(=$F>)?@%+3&4=+58C#8(=16C;B'*$5<>@CCDA(*G8;*/&6/8;A.')=4;)>>8&HBG(0%'HHCD&-)!32:*,"G&
@r1174
CCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCC
+
-1D?&"6@F,'@@.A-GGDH=1A4E*90H).!59+(3G0$03,=
@r1175
AAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCC
+
)D3".H41F"1$$HA808;/EG!B7)H.1AE/.67C+%8+9$C7<)73G'(=42
@r1176
CTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCGC
+
/0#F!67!841@=)C/EF&30H,<1,6,;/4##?!-64H/<>F1=4>7.21,=7$7,,8#.-+?E27>);-8%3@*,>,5'26&>&B9**B$?8/)6DD18?;4.>79B;?<?''1=*,3/#71;E)/*?G<5ABG.,D-*;:5=&+BH=#:D/?;
@r1177
GCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTNTTNNAGTTCCGGAAAACGCCGCTG
+
*,'<9;F#?/4B'9,6E+6:C5&D7,,(AHG8DB>:#F?+3E*75*1#&>!,D8E4/''?9<,GC
@r1178
GTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTANGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGC
+
7+#"7B;)D#/38(??!23H*(DH8G-D=/E$'.#0,-@1(:H$;,42"G:B;!8%F!=!FB9FB>,2$2628,*5>8FH2$<.0&&+B=3$AF#G58-F91=
@r1179
CGCCCGTGCCTTATCCGGAGAGGATGAATGANGCGACAGGAAGAACTTGCCGCTGC
+
(:$BDB*C,47E30F91,<=4E>69=/6%"E(<&!DAB/'<%6#$C9'/<"A$6'3
@r1180
NGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTNCCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCNTCTACATTANTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGNCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCANCAAAACGCTATTCACGCAGTACAGCAAAT
+
&25;B=4'5#!A?3GH38=EF1F7/<;+!#7C"B>=AF>D-7&F&-D+@(3?4*'E<B74/AG.#721?>'="8*+6.>E1DH'C%02&"0,1.3!E!)#?8DB1%&?;CGCG**=%.,70=!D86&2%0@G#?*:!)&;%0DE/?;7:335"&0*&A4;D)%"B565/B9/;E2'F,GF'&%!'"!A9';+C'EA+H4$8$+;0='C%?9#'=@BG1"5*,,-50(%01><>D7%E&H@A;63#E'CB6"3H=+*??/)"2>6*+=5BC$''EA4!#'C7$9=2?G$(G1D45-G-:!G"$8'111-:6@AB20
@r1181
ATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGANGCTCTTCGAACTCT
+
<)D;*&-'"B7AH741+!1A'++55)88?-:CG?HF%"7%B$%*+4-*D7-BA.2
@r1182
CCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCAC
+
/A6:=?#A@"AE<G1<="8&=26HH@03F?H+G<,D*14H8A!(EC?A.4*7/&>70*7*#C!,*2<+A1/H@9G42$:=-)"@(;A+153AC
@r1183
TATGTATCAGTGCCTAGCNAACTCGGAAGATTTTTTCAGAGGGCTCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATTAGGAGGGCTGTT
+
.;%"4?-GB/A'?4H4F"9ED2+8/?.)B9C+9AG.205H)GH)?034?9)G3),82H*F%*040!=H8,8D:<=A-<3$)0!2-.21:,.E',$'(FAC,3?H#=51H%%@D9.?B),/-H
@r1184
NGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAAC
+
!=%>2'8#4HFFC!(;:?7H*$76GD"#&$G-<F+*5*B$%3C6E=HG+72+/%/H.)EC
@r1185
CGGAGTGGTGCAAGCGTGACAAGTCCANGTATGACCCGACCGACGATATCGAAGCCTACNCGCTGCACGNCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAANGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTG
+
+#"")()+)($%&&$!""')$+$+!+))!"*$*#$*$&%"$"))+&*"&'''*!(!!!#%*#!+"(&"*((&$#!$))*"'+$)!%$&((&$%#)'+*('&'$'(+*'(&($+%"'#!!%*!+#)(&&%))!"%)(**&$($#(*)""&%$"*(#)#'''+&+&)"(%(+*$#*!$&$)%%*(#$*'&"$$#($)#)#&(!%(
@r1186
ATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCT
+
%A/35#$:0?*."-<--@)F:-@>@:!G.;H?7DEG,<'@H!=#5+@++:%A2!/BA=F2>::'6<4*9732?E2-1'<9>7F$H+3<7/9G*=E4:8678%0@>@-&2&$@.6//E.F"G,C5=,2.9!8;F,>(,(:,60E3':,;12:2
@r1187
TCTTTCATTAATCCCTGAACTGTTGGTAAATACGCTTGAGGGTGAATGCGAATAATAAAAAA
+
79D-"85#,7C+4.C06%A0;+@/<C<)B$*1;;C@6,FC:E2*>H'"70%#>9#H,7!EB<
@r1188
TNCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGC
+
"2>H(E(1%D0=C!;H;D*E1,GH(C2!7(1(-%:<G=G',"9##4H31-CF#/G48:0EA72=F?;<&=!>10A7773D6!@
@r1189
NCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTNCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGATTTATCACTGTNGATTCTCGCNGTCAGAGGNTTGTGTTTGT
+
%+&%&$!"&#*%+"(+$))!#'"$*)'$%%++($++(&(%&('%!'%$#++#(()+''#)++'(")$$'!%$*$')"'$**!$)#%''!'#+#*+#*)#!$+$%*%)''&+(('%%!)!"$%&$%$('!$+!')!*+#*%'$*(*#()"%$#"#'"%#$+!&'(+$
@r1190
ATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCA
+
F&,A1$=1H??3;C;(4=79%4&-.',F"8/7CBE4-:9/!2;)?8
@r1191
NTTCACGGTCATAACGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTGCNTGAGCCTCCTCACTGTTGAGG
+
&)+(""("$"!")$#)#&+)!$$"*#)$$%"+%+(+%(%"($($$'+#$')+($"))(+(*+''%$'"!(*#*#**
@r1192
GGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATNTAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACNGTTTCGGGATTGCGTTTTGCANACCTCTCTGCCTGCGNTGGTTGGAGTTCCAGACGATACGTCGAAGTGACCNACTAGGCGGAAT
+
"(&+!+%(!#!#%()'*#!$%!"*'&(%#+"$$'*('*"%)(!'+"*"#&('($"!#)"%$**'""+"#$&!++)&"+$!#""#(%$*#+'"%&#("$&)!''")''$%*)#'*")&%))'#"(($'&##"'*%*#)&%(%#$+("%"'#%"(#&*&('#+!'!"*!*$(&(%&&&!(+%%$!)&*"(&%
@r1193
GCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATNT
+
4/%:&:<D&DHB%@FHG/.!E!D$G4&$$;'>;2/69,&G485A><E/92<=?&;:20;6<B+<#ED-C</C131H2-:<?090(@$00:+8CF1-4!D"::6D:CA'1%B?;8E9&!A?&%02$8*'7!"/"%.G*=#$H!+8?G3$D4#D&>-1HD269:.HE(=;&>23!<5@H,*%(!&:(0<6;#5!5*8AB:#AC"<3*.H)*9"#-,(/E4>9DH.:&C.(*1FF!)#":5"""EF*1+/@-<:
@r1194
GACTAAGCAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAATAAAATCGNAATGCTTGGAACTGAGCAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGT
+
&(!$)#!&+)*)$&!!'"$!!!%)$!"$+$*&%&%*'''!!&*(!*)'(+*&)$(%"&"&+%"%*"#*#!%(%)*++")#!"+*+#+")*'))+%#!("%!++(!%)&#*$'%'!(!%+#&#+"$"('(*%%'+')$*$&+*#*
@r1195
GACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCT
+
*73G@H214(($"(078252/,,C.-(.C9>(-88#"(H'0$(A-()&=;?)5G<6$6>."3$C<*4;+FH3"?7;@A,!GBHF,F:,'92'GH<GF,;&D*F>3"!;CE8=F772?;7,0<AD/-5<B'73%*71-0273"$2G-+E?7$GF2>%*EB3?4D42BF;>F0;#
@r1196
CNATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTC
+
%%*C8!'.;3C0C>(0F9*@$?(86&0&9%C*.?(5<G*8G30(72@.,.F99"EB0693%C8")H-=>H.!0G7?DA91C4$&9?G&6<&+6=6C8/$4B>%3*?$?9-<1G:>FD):&-7C455#2-$;06!B;2.-"
@r1197
ANNGNNGTNTNNGTCTTANCNANCGNCNNNGTNNAGNNANGNNGANANGNNGAG
+
#!!$"$###$"#$$$!#$$$!!!"##!#"!#"!$#!!!#!"""##!#!"!"$#"
@r1198
GCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGNCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATAGTGATCAGT
+
@H13((&-87$,-%'/"*=9>8"H;5'9<4)&.57:"***+H=,D+14H/DA00%&#G?:31G<%(,;E#9A'@'$*?D>.4+4'8-A7H5>G1(4,>'066C12"A/7E.
@r1199
TGNCGTACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAG
+
(#!))%+#'%+*#$$*'"$(""####)!(&*!)+*(!'$!(!$)
@r1200
ACNCANNTCCAGCCTCCTGGAGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGANAAAATCCAGNTAACCTTCCGCATCATCGCTCNCCCGACCGACGGCCTCCACGAAAGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCNGTTTGAT
+
!#"&$!"*#%)&")*)%')("+*&!%'$&%&"#)#$!%*+)+*+**!$)'))%(()(&*))*($+#'*))!&!&**%%"!%""!%"%!%))*!*+#(%!(#*($'$$'#+++%((&*!)&!!#+)*#%!')''$!!!!"#'!($!'(!)%#+**$))%%*((*#*%'%*)(()+''*''#&)'("$'("'#%"('+*!&#&')&(&#'*"
@r1201
ATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATG
+
@64%2H/*@92=(E<:H)92G'@'$3=8$3!+'86,ADB54194E1./7H#+9";2#.B2=0%F/-5F$64G!69?D:2>30%AHH$58EG@-?>5%36&?%<1'9FD@13H.2AE>'$8'%BG,H""*E6,%&*+(,@-
@r1202
CTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACNTGCATACGTTGTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAG
+
'81B:+:2+%E?0@*:>5?::%5F&<$A@H&G'/F2+C5:,0>=AH9.2"'.'(;5'"0ADB%E'2C%$3(%4A-E5(D2"@#743417C69:#/
@r1203
CATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAAACATCATTGATTCAG
+
E<=."A7#/C;?$#<39.+2-A5(D4@!&:@4)$=9=,?E87,$02CB0DG)?9(1.1H&/9@?#+/*42!>(;!8(8#GFB(84+*1AB6B<#8"A:4BE&2H
@r1204
TCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACC
+
7-*&&"?04!H("E25"0;"AC>%(BG+.@4(40.>H%:9BF6!>#A>HC7E*D7C(?E-;&'3(04A@:&8=?<<8<?(*9G-<-,@58'5+%9EH2=+2G21B<FF2C8/%7EG8=
@r1205
GTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTG
+
9>-+')D,D7;5E8496E?4B+;1:>6A7=0=&#$,B90>'2&06D2&#&E&;<''6&:#G+G.-6H)5G#B<F81>"/G+*9-6;(;.>)%<.FCD5)C'#$!8)0-BB(7;42!>7(CH0%'+(./6"&><6"'$%E2G3.#82,4H>5&AF%B0+G#?&=,42.7>(./5)
@r1206
AAATAATTCCTGAAGATATTAAAGNGCGTCTAAAACTGNTAGNTAAGCCTAAAAATATCACTTCGAC
+
:/"/A1*=7@+#2H;'+H5/06"3?!E%D=9EF,C.4.;=:"36-&#B94FHF&0.!;$."7H2,33
@r1207
GGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGANTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTG
+
?4@80GF#>''.&7>:4A4;D"BA"G*99./5+13/G8F'AD>H',G1=A#=:?6<A;/2"!";49:4<6CC34C4!;:#F"67+(H3<EA-&HFH>9*CD.%9%@8%?-4(A**)">9/*EE2F6H,%"$BGFC:E(3!(@2&//6+BDH%9"HA3G?0A<@8A6@!5123C&$A&<.C$2F,
@r1208
NAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTCA
+
)+$'''+&)''(!*+))!*)!"!&#*)"*"#&(*+"#)%$$)!**#$$!!#)+%+%)!&$("*!*#
@r1209
TTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTT
+
H;1$<91H=(.:!GC+;5307:0:8G,"%B?G?@)A8(B)?6F*>A%F>GEG+6DBB2,.C.+G2<>C7C#F47<!3(G&A,':D;%4+>#F(!4-?8$!+)7H3?>A3CA'?20FG?*BE5FF#C+G-4<4!H*&&8!#,)#3*4B0<)%#8+.;+9#@?4!E:>'41EDFB-$28E8&9@-?!ECH66H(7@,C4B2%A&<+D"089$',*-?=2!4%:$-/HF1@/D,%*$=!3"8,HG#H19896@8
@r1210
ANNTAANGAAGAGCTCTGTGTNTGTCTTCCTGCCTCCAGTTCGGGCGGGCATTCAACATAAAAACTGATAGCNCCCGGAGTTCCGGAAACGAAGTTTGCATATACNCATNGCTCACGAAAAAAAATGTCCTTGTC
+
&""(&'!&''*+*+%&$&*'##$#**"+$%')")+!*#!!"$)!"))"'&!*$'*#%$((%#&$#'%!+)'&"*!%(()&*&"%"##!'"*+%*#%(+!%+!&%!&!*$+$#$&#%)'!!(*''('&'#*$)$)+
@r1211
ATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCNTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGTACTGGAGGCAGGAAGACA
+
,'*$!310<0H5-((8C#>6@85)=E$%H841,=<>B5*BG.4)E5A>G6A1#2/8;<F5=0)$,B.G:80-F.6G:"%&E=/(/G3@=;=)F<0-D*$04#93C=89#>D4>/:1
@r1212
ACGGATGGCAACATATTAACGGCATGAGATTGACTTATTGAATAAAATTGGGTAAA
+
.'#$C"49D5>@3163"35*(7@.?C/%;+D+:2%+"DB1EF-!&69818#0E1??
@r1213
GCTTGTGGAGTTCAGCCNATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCG
+
<!,'.<:3B;0(#!C7&,<00=H=9+<4!"/FG+5E@>C/)H&FF*A$7$"=EF-@4$5A&*::0B>)B1@44>:'H58F"8A9:0'%,G2$'4$@)5;F1?2&=()*#26484=F#43<*-*9;$F$&G)3FB#>;F@)E:,*')
@r1214
NACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGNATATGCACTTTTC
+
!'+&!)%'$($($!$&$&!%)'&"(*$(+)""+"##!'+)(!&(&*)!(*"'#%&+')+!*++"%&(!$($()''
@r1215
AAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTAT
+
B4'2GD)=;%H@%<'7'?'9C.%:1%").5#HD)+AG$/@)F%A9%+@7>89B#<'F865BFF(
@r1216
ACATAAATACCACTGGCGGTGATTCTGAGCACATCAGCAGNACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATGCGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGC
+
7*G(A:F/+=B#/:1+$CED/+B.!/2*2F7**9=9%"%D&83/G$CDB!?,+%2$+HD2F!@64+=.*<42>)5E4?G"A%/?CF3A,5HC#-DB3,!8F(+&F$+'<3E"1!HBGF50$/"F;#0-*+#*2@*:2B0'6)$)>.B-F5C1%C7?!*,3:925.8D5#%3:,.@</8F0.?/(AC)"*:)#5<93&$G(!#1.";"&?)78;G.F-+,3%8,AHB7:#)#/;%&-H?@">G.."135B$!7!8=(C*)<->?-'/H0%./78$H65/:(/2D8':7BG;?GD!1)D-/G2+7/1H?9%!<"!!--2056!E)&:*@=1**3E*6EA3353A&0?8/;HEH,"-*@A&.//BC8:F<3!;%-&CD@?D)%@<G&4D2!%E(*"7,G#5&!.5,?94
@r1217
ACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAG
+
%4>'=+E>'=#/-,A#5&F<(!>86B60A0A.";$%;)(5B9&5@78;%H&1
@r1218
TATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAATAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACANCGTACAGCCCGTTCACCACCTGGGTGCAGATTNTCAAAGACTGGATGAAAACGAAAGGGGATACGG
+
G'HHG$2--'G-$!F,=DHDG(*<=,>/(+>*FG72%-?$387&;"7)3*D,,;/<F1A.+E-6)7)*,9&/;G75:-7"/"4>#<E<-:DB$"!;1AE)=F=F&#2-#G>61/>>$9"!&8:67);$C*B00%&<>0!$BE#B*H@(*"&FBCEC-)G?H0;<(C=8+*0)1,%C'/=-@B05">#>85#=328(0""%35,9*D812%=)(,CA)@E2>>.76D#'D#'@/#29&F
@r1219
TCCAGTACGGCTGCACGGAGTTCAGTATGNTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACG
+
78F4F$'$HC?C.%0#006;"0+*F.%%9A#G#$:,@DBE6*HB<><E2!!)%'HD)+::FB%.:-<#='"=9E#=#6&43,=-GD=<@E%4-6
@r1220
GGTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCA
+
$"F#C-*34E(B1%0+5G16'.46'7"?+-&H<$*()7!&>E3
@r1221
TTATGTTCTNTACATGCAATTACAACATCAGGGTAACTCATAGAAATGNTG
+
01/<&1$#E)#?G$#92(D38:-'*5.*!&&:1@.='FG>>#3")',1&<B
@r1222
GGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGG
+
C,67E@62CH';6>)(<#-3;->=!6*:A8.<+!=)!-B0.EAD=AA983GH!5F#C%?C4:.84/1
@r1223
CGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTT
+
9CF,C8"/H$3<=:!;>%5+F$4@@63A@0-C%E$50?@,"2-1F"(-GE.508(5E3$90>3:>)4<D2"%<
@r1224
CAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATNTGGTTGGCAAACTTGAGTGGTTTCACT
+
97#?,6G:#4?BG+@EF97'&C"6;G.#8&DAB*,!*'6!,%>"6>45CD!A89@F5,06/CH3>H@)5%4A2
@r1225
TAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCNTTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCT
+
B1'&=%5,4'!6940#F+B+0'@2:'9<&041@E1@4(*;$C,+:(2)5*3+#=8%#8'"*/<6%-696=0=/07."F-887AC8$%#4:/>'".*G*>,273*(68>9$CB=6?E=*E>%,)&3#*<?1FE$<#5-.H#0B5E=<.")$3<@3:;/*<A#0F8D?B",8F,:"%<%D*H#%?D('0(B9D"$@!,<#<>"(42<;1
@r1226
GTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTNGTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCT
+
2+*66%!7C87648.5??-((#;14>%$#.2;<F+&?=$"-(D2FG;,6DGCF(;&H('#*A)9!*6?6;F(A9=,/+*-'32&(*,?68-
@r1227
NANNCCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCNTGTTCGATCCGAAAGGCTG
+
)""#+$(+$&&++'$$&!(!(*$!#$%!!%$))*+*%++$$'#(&("%+'&+#($+'$+#$(+%("!!*#+&#%#&%++&%(
@r1228
CGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGG
+
%<*.<($3-3<E/!<>'8EH2B@$9481@#4$60;>'565:H(C@C1<."66,7.E3!595&D'A"$D:'A'G,*,E
@r1229
ACTTGTGNGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGA
+
B.:0:B6;1/4?:AA0(0!/;C;1+B3'7C35A'@79,'G*8F3HG$,<,1#13EB'>-8$<(1?1*'C/<63?%B=3
@r1230
CGACNTTCTTCCTCGGTACATAATCTCCTTTGGCGTTNCCCGATGTCCGTCACGCACATG
+
E?$),6';;3977:GGG+9'@?*.*.7;"%(A%H"2-=%5<'!01>%>0>3)--777@;G
@r1231
AGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACG
+
6=C9"F>0.$>69(G=.@E+$66+&=A)).G,3++9E!(3,;=D
@r1232
GCCGTAATTATCATCTGCGCGGGCGTANTCTGCAGGTGCCGTCGAACTAT
+
@H%;$F,B@,6:FH'"?H<*-:G:'4G!(4&BE0>2':8<6"$0:AH053
@r1233
ATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGC
+
&?$1F6.F/@(*.<:<*@/'G+'3DE96FD2'B1(661:AF@=A')0&%*8!F+H=5CB25%'#.F;
@r1234
TTTATAACCNCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTT
+
E:.75;(8'/0-</2H!*!B!G<'9:E#4CC$7G1A%G=#4&>$:7?6D.=504,<H7@(4.)0+!0<$"</CB/E$094(HE
@r1235
ATCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGAT
+
(8,*082E"0&)FCA?##).)@9#5A=69$"H59!(C("F#G:CC:BA,1(:>-AA43G,5.=#./<?."?(.?
@r1236
TCNAAAATGTCGTCTGCGATTGNCTCTTCTTTGTGGCATTCCACCACCANAGCGTCATACAGCGGCTTAACAGTGCGTGAC
+
"#"))+$$+$(#!#"*")$+"("%&)%)#+("##&"(#$!'++(%++$%!!$&!("#"&"+&(((%'"!&'"(*(#$$'%%
@r1237
ACTGCTGAGCTGCACCATCNCCTTTCTCGTTGTNTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTT
+
9H1*$'H&H6@D8>88?!;4"<A?;*-=A"2(52D-:%<,.,,323('#*5?*7$)6>&.A6C/'6>(0')5G188=)-58.?B>-@1.-/2@=-H3-
@r1238
GATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTC
+
CAG$;0+.&$22EF#%(HGB90GH4&?G<+$7E$G"=.-,.0C;F%=.;D
@r1239
TATTTAGANCTNNGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACNTAGTTTTTTGATAGCT
+
))*(%(%&'"$")#)++((#(#'($'&$$(!*++&))(*$($)))##!"#)(*$#''(*!%"()")"#(
@r1240
TAATGCCGTTGTAACCGGTCACCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATNACTGCG
+
6-:%37#A4+&,(0HA6DE6@#F;32)--C8$';G)$&-<C!.@?=H2?B>B(B##2H4=BAD+"4'%-#F8!3>=,;!#&F63+56-A'6%4E0D=%4C%48,?/6-7BE2
@r1241
NTCNCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCNTAAATAACAGAATAAACACTGCACTGTGTATTCAT
+
$$""&'$+**%"$*#$#+%*"#'+(#++"'('#"##()*&!*&'#($++!&$'+*(&#("(!(&"$#$((&'(*%+'"&)"#'%(%%)&%!'"++#%
@r1242
CGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGT
+
)35<7H6.;G5=G5D#!?$9>1*'&5H@H77E5+9/=DA;'3'+9-"!1/F1(;G*;B'+?H%=98>B>#*20*<GBEDB;E+6%5@G=3?3/'=<HA350/B(C>+.*/C9@8,@$<9%-A4&95)!'%,$!6>14<-02$(*.-6G0($&(19?G,#!;*.'(4;3'*=5&21F8)%911#:<C7=."&9/;:-H&10'+:GH7:'C**9"6&",%8:%7=-2BF#7=8'E-,.='2/*3->6)AA!9&F8)+3/:#91;11*9&C%
@r1243
TCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCNTCTGATCCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAANTTTTTCCATCGATTTTATGAATATAC
+
0'0%AC:5/4#0-88G>HA/22#"/;:0H)$3+E=G79(5GH:1.$3+=$>H-87&;*4%,+%@-DDE#3%5,A6DG"@&)'E=G(F@H"-$#2&!F(=D239@G4@9@-.+1/BB)9-(;1:
@r1244
AAAATATCTCCGGCCTCATCTTTTGCCCNCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCC
+
2H!")?716'<24=9$83;:"@/C<@B48%-2'0"B3$FD2#?<7D74)(-#/9,.)"?6.1>6@C:G.'B<14%7!#5@E/C(-;H9E::23?,)"1'.=B=#61$C-D,-A49<>0?+95!?&+E<C=%49)+-97)3755*GG70;=C7,2545<4&DH2@4'2D4HE2GB0*&@2($C280.1<G/2!6103"CH6E%266D<?(C:>=<2<$0,G#,>+E=";9D**<&&6FE8)"@$@5ACFD;8>B-'4;"&7-6522">
@r1245
NGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCGACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTC
+
)G'*G">@)+!D@->)A<G;A3)*<;5"1D;@&+=6$7F-7G=+;,?*F+)!+>.2."B=,6*CA4+!G'?>$<0E<EH5@D3@?+-*-$>
@r1246
TAAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGANATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACNAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTCGTNACCGACATGGA
+
B3&6C@75,,:#A,+G2*F8E&&'#)F$!&<,A9%:E&'0+19CE,08?HH%?-:4;."0BH>/G59FD+)E?>57<G@9,).@8/C/0#D77"<C;(*.:CF5D(0@:4BBB;>".>B;."0D,1(DH5+:-H."&4+#.,:(4="'"3FG8.=A>>5"9?;*5(,B:,+E*6?-9%.'FH4<E.6$>H&A$*/@E?-<6%F@<C+7748*?;*%-<8#*5(:H*&!E"C59(5/++!:
@r1247
AGAAAATTAAACAAACNCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCC
+
6G),('F)&.)G4D!7G7-#+6(8))6.:"5$&"2010)FE@G-!(<(3E*#.#>8>%B!,<F/=$3/HHHHD&#@)+&?>?%=//-<),+0F.+B8@G,;4G4-#9G1144G0D&2
@r1248
TATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACT
+
1G1F4H6$4>1E>56',B78$H;*E2.>*$A":GD,9*"F!C=6FG>
@r1249
NATAGTGATCAGCCTCTCTCTGAGGGTGANATAATCCCGTTCA
+
#://+?8A3"B?2*505769D0/H(&H;A=.->)&#)91/B((
@r1250
AGCAGCACGCTTTNTAAGCCATCCACCGGACCTTCAATCCGCCCTTCGCTGATGGCATCGATCACAC
+
+'*#*!)%"!"(**(!"##!$''++)#%+#%!"++'+('%&"%"$"!$+++)")#*##("(+')"!#
@r1251
CTNNGNNCCNNNGAAGNANGCNNTANNCTCGNGNGATNCGNCAGNTNNNNNNNNTANCNNAAGGTNCGNNNNCNNCAGNNNGNCNTNNNNTNNCCCNCTGCANTANNNNNTNC
+
###!#!"##!#$!$!""$##"#"!#$#"$$#!#!"#""$#$#$#"$#$!!$#!$!$"#$!$"#"!!##$"!!#!#$##!"##!#"$$"#!!#"$$$##!$"#!!$#!"$$!!#
@r1252
TGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTGTGGTTGCCGCCAATC
+
4$08,???EH+B2'$C&./5E4%H>A@&H?>A;)5H!909G1+%G*.<48<7!G,3A6E4@/256@0@<<;'8!
@r1253
CATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCG
+
>DC3/@0">B/+@3DE0(05&C823-7-;.))6*'C4D"45;>H3-*H'H+#'(1G2+?A#$<D!D"53,+2/#9FE)GA!%6;H?/"D$5G
@r1254
TTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGCGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGAACATGCCGGATTTACCGGAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGG
+
,DB0A!!D$3/)E/4@B8FD3)9D@B3%,")!=7:)%01&&-''=(..>+B/%'"&@=H&.&:-)F5;.D;C+=/>5A#5D'&7BAF$0+-9'#?H4/,8//C9:(@'(,@E-*C/CD,3'CA"9GH:F"&4:/(=7'H/7+EH(?5080B1??H=<4C/:,9@F6:H&C9!;=8&)3+'C5;?'?>(8=G"0@.%D<';.A";
@r1255
GNNGNCNCTGCGGCTCTACCATATNTCCTATGAGCAACGTGTGAGCAGAGCCAAGCCACAACTCTGATTTTA
+
%"#$$#!+"(!(*"(+%!!)#&((+*)'&"#!&&!$*+!$(%+"+$#"#&$(&&'&(%'#%+"%""+!!%)+
@r1256
GCTTNACCGAAAGCNNNNNACNCATGGTGGTAGCAAAATCTGGATCATTCACGAGCGCTGCGGCCAGTTCATTCATCGTATTCAGTGCG
+
(##&!#&%'!*%')&#%&#(#"%)*)++"*$%!$(#*"&'##)")"($&#&+++&"'$''**+)$$)()%"'$)(+*++#+*%*""($%
@r1257
GAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCT
+
'?@/21%0B5+8($#/6+H'"(B-6A4A!904$H4'86(,*$!H!F5D1H8#
@r1258
TACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTNGTCAT
+
*56'/7;@.-%723#&+.F7(!3&0>1;""!-0:1'/'#?7;+?
@r1259
CCGTAAGAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACC
+
@(:?%";;>!D5H$D3D".!0&B+-/(A;3E7A1F<==66%&"GC)5E7-G/D8C?7/B9(><?<3/-!D6"DG'=*.
@r1260
TCATCAACAAAACACAAGGAGGTCAGACCAGATTGATACGATAAAA
+
$8E)"/366!6,&$H9!;>)<A'D,#9B=CH.BHDFC5G.)(,<D#
@r1261
AAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGNAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAAT
+
/6559,,:/*/0%C6F,").7B%+3B<:G6D')&,%3B6!>F+7$BBF$(2F$1024DDG>(A</>$04D+/0/@@11C>E.<D'?8>E!4211@FF=%E.D#.7!G;9/F-6&E;0)A#G'4%8<;@/<@"6%=5%%+<8?0B<&D8+%&A0*G<E@/,-'@51,7+@9>A,@%2=1#93';!!)(=@@3:%<#(A14B!!4$*>(?&GE(G<6D&=4>D5:#
@r1262
GTTAGCGCAATATCCTCGTTCTCATGGTCGCGGCGCTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATTGTGTTACCAATTCATGGAAAAGGTCT
+
0'%#30:B4;48*A?A7>70$G>09$<'C3;+--'>#7,&=0>2E924,B==,&&4?.0/B&5:,5GA#/CB'"91(16):?%%#(A*FE(/C5/7:%8;70D8>..+7E'$(7<'D
@r1263
TTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCCATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATNCTGATATATTTTA
+
.'C=.#&.>-'8-E-"4)?5G0G'8!)=C'0(A"+""4G-$=1(5E&A.58-CD+@5;E:!,&,8>>#?:0;&&D76@A00#DA'D'@H/37C=C2D>B@A@B*.1(C&$C(B<&=0:@3$?>#"F@,+6C#+1G5HB'3H7F>@D@3:5959<+F>)@0457+@/?G72$-4-4H&$/41<<F(,F!&'7%D.@9
@r1264
CTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAG
+
EF1@5!$B;91E)<)C(3.?>$54.@24.+9>13BF&-'$:-#(+6$*
@r1265
CAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTAC
+
C:4G?E4-'?6/3H29$"4@F.F=2:D#E?3HE6=2.0D1B8?,%,><?H?
@r1266
CCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGNCTTT
+
1;,;6A&=C=B)CG,8++F$<#5B"#-F03.4%'GC'.C7
@r1267
CGGGTTGTTGTTCTGCGGGTTCTGTTCTTNGTTGACATGAGGTTGCCCCATATTCAGTGTCG
+
+(%$&!)%$+(%+*+%(')&)'$"(!$)!'('"%"$+!))%'&+"!!%!%)!$*(+$'*""!
@r1268
TCGTGTATTCNGGACAGTACGTGGAATACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCAC
+
2$&:B)!@/=3*088756@6>!/?5<AEG?$7"/!4A5-07E?"=";A2,3?#!'HB4(,7C1-:/&0;?&=;/$385?7'*,G/$'#E
@r1269
TCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCT
+
H>!1F&"85//1>741C,9GC#B!8D..49C##D1;0!1"1)(/E=F5!(!H)
@r1270
CTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACTGGNTTACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTC
+
>)"=<)3<.H@9D8!2D<FA,F46#1<15@HH>+'7/(>9@/&.+:?**21?0+)0821+1AA76G*79#="4)&3&!!@G+6@7HG3=:F2)G/5;H&%!/F303=2'7C567<H9<)H(<0/-8.0G9,:
@r1271
TGGCTCTGCTANCACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTNGAATGAT
+
,/'1F74A>?.'8'B%H:5+CH<E?/6:-(%;A5C/C/F"A$-/+)63$::7H4D)7&-D;(G'/:/9@0@H62264C>2#7.?E10?(;"+H-);B$&3E";8HH<2B,,B1
@r1272
NNGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTA
+
''+%+$)$!)$!+%'!&&$"*"$%)$)&$&'$+##('(+()**%*(&!"&$""$+%)!+)(('
@r1273
AAATNACTNGGAACNNANCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGNTTCATCGTTAACCGGAGTGAT
+
)&))%*)'%*'*'*!$"!("'"+#&(*"&&$)'*&+!)'*)+**#(*%"$&"*#!$%$$$&'%#"+$)&''"+!#!'"'))$'!)%*&''%%%%%&!!""('$%%
@r1274
AGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCACAACAAGCCGTAAACGCCTTCATCA
+
(A"E9467CFH-/-$:$-/!@@=4-5EH5>$3DA>G-:<!8AG%DC%?4FD">06"5$-%1(*1?&C7C47DD,AG@.8=)@8F+:)G1,*F'):H?%)$G?
@r1275
GCTTCCTTTCCNTTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGTCGATGTGCGNCAGNGGAGTCGTGCNGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGANTATCTCCGGTGAGCCGNAGGCTATTTCCGTATGTTGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCNACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCNGACCGGCGGCTGCAGGTGCAGAGTGNTTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCANAAGTTCC
+
@C7>636.G564??2HA:1.?%4B:*?/1F'7(=>5>7%!+(>5%69'+,$&@2+')7A&?F(480,)B://09-7@:&G(2(-+E8;714:E!#D;.H/$523""A")$!:2H>)CD$%F./!B$8<-G!<=:0.==:1/-":7/)C.DBC-?0E?G%-71)F6-<B(<F>>*0H7-HG;H/-4=#615%G"#/F7H"1<#EC&$:)#=28.7*:(%C>8=6C'#G1GH93BD>",,/5A<=A+=+0,H=??!"GBD$F',3A2392/#'8=D@=!$-5E5C%A<?8&>D@/GA<F9:E&%-<$"12?.@CCH=GB:".)!$G!.">A";D1!>'65.E0E?,<0
@r1276
TGGCTGCCCTGACTGTCCGTTTTCGAGAAATAAGNAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGNTTGCTGTCCCATACTGACTCCA
+
>D2)0.-%)8,%?3A+7%84%49F26%6&<#A86+/";G!F5-3*1+..8'#&5?,759>!AB"G4,-'',..-.<9"-EC53A=9:3#9@1&!G<3@D$79@'1$C
@r1277
TGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGAC
+
AAC33CBE9EG.88<AB:?;EBB'>0%$?58'?$+H+04*3D46:@A7A4>B7+'6:+.!B(=4F:DH60/1!E<(A:,BG3C9252C
@r1278
GGCATTCATCCATCAATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATC
+
AH*787@CG.3166!,8G+-7;F7:.#>;6.(:E1&@+1.!H4=*+#(.8<,C%,/@H(
@r1279
NGGAAACGTCTTGGTGCGGCGGATGTGGATGAATGGGCGCTGNATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCG
+
"AA'C1>:60D6=G)48G-2E$/5G#E08.E/56&;C;H"#/8:HD1G'F8;&6$5*'>0&3(9B1.>$3E#*.8$6.%GG3#2:39@::9(:E5$E/E/=?@H
@r1280
CGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGNGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCT
+
!22E52F1D'6CH(4**$.6+!@#3'25(),#E(/?29,E3(@F**;#,;7'<;">@D>;':(#:5CE>B'$A+:7A1;)"7+0)0C-G5*&%)+4,0*B.G<)4(A?G:9
@r1281
GTTAGAAAACGATAACACCGTGTTAAAAAAAGGACTTAAAAAGGTTGTAACTGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCA
+
1)$35?G"=9C"D+?'G8920+F5:C!3C?8==*=4&81,8&">FEB;3")1;D96>92%#H*G49=),F.A+:+*51D39"*,8DDB"AB2;E*525$G""E"%-4@6.==7
@r1282
GTAGCAGGAAGCTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCT
+
:H=55@72"?.B$A".:G0D/;B#G1-C()B2$B"&89)&;2;B,9>/F0F$5(>>?*FC<>H?E2/(6$G*(0&>">,#!"2=),($@36'A8E6++#):8&*<30,?'6F#2!?=$-1#,C1%=
@r1283
GAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACATGACCGCCGGTATCGACTCCCAGCT
+
?#:.;CH//E'03:B#A1(/@B6%E-)2#0!;E2"G4?;&-%0=??9B@>&"?99#',*)9!HF:
@r1284
ANTNTNTTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTATAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGC
+
&$)"(+!'+&*$($)"!('#$+$)*&#%'#'+((&$%$)!#&&"!$)()'$'&(%*+)")%)(%&'!*&!"#&%($*$#*'"("$+%*&)"*$!++))+&$*)&%*!(+)%'&+'+'*)%$+#+#))(!'$')*'*(!%#*#)$'(#!$#$"*'&'('+)#&+()#%""'+"*'&&(*#$)$%%(&)&#*"%'"!(#!(&++")"&!*&($&&""('!$**
@r1285
AACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCNTCGACGGTGCTGCCGGTNCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGC
+
E!#FE9E$F($/&>CF"H++886--6',5!%@F((731A7?/<<#)@;".=*':HE'+;91&0,=)G7B@=?3D@1<23$4!+?"D814<%E1H,/H!'%/./477B2@6EDD+A<$/0G9!H@&
@r1286
TGTGCAACCGATGACGACNAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCNTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCG
+
2C$43$B6&,$A!'?E*)B,,1EE->9$>+.:/"?!)%&E-#5:?%",?*9D)F$HBFC=$9(>.$4+(,7;-C"=:$F,,:*'D&?462&B-7"E49";72$BGB?<F!A"(:/C<'<)--8@")"F89E>$#.<A5
@r1287
ATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTACCTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTA
+
6F3%,.2D?)4>!G+,4B;8:=#E;/+H5?#E(>@-<#-&4+ACE&613';<1"=1A7B.(#,2#)"'#4#*/!01#AF()+&=DE8,+):
@r1288
CACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTACGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTT
+
5!!H'(ED13*20?"C39DF@$C=B&0E#F>=%#DE"C;F&$C5B*(3:<(A.=:08,%(23!A%,@%0.'@;>#=6)151#0BFCC<BC+51D7C".):)8:A5<-#E'&%'D4-)59&:
@r1289
CATTGCATCGCTTCAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTTTTCGTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTAC
+
&D:-&-B$,F;./@.=G=@;#E%)!(:A9H;H(>@(=;%/59G&D$72B:B@/H5,;!)9)5$(=<4:G)@%:=*!,F4?-#@2GB87'<$>F76.:<<7&D,@H@*<+#,2:/3+2,<>9"1>+-*'%+'2".5A!(6<D'47+#(6!/7'H9;#(.',(G1175!#':>%491&'<29-*H%":F24B9,-.,%/46*0:9#C+5:**'4
@r1290
NTTCCCTCCGACCACGCCAGCATATCGAGGANCGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATNTAGC
+
+;43#)3.-%&"6B)9(D4725="6D*,#6BFH!G8(#C14-44?1.=E;--!$2:864;;$'*3+@C!'2B5D>*>'-<%FDD=('879)01802E$F!H;7D1G3<%"-!G*BE4F'8E:+0;'(.@1<
@r1291
GNTATTCAGCCAGCACAGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGANTCAGCGACAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACA
+
;6ABHC4*>"!="?@%D5+)12GD9)@55%"><):'@E94$.*,4;C?9<)-'=@1@HA&8)H8.;HD*+:G>!-AA?=$G!-)H?&+F'A0316#)'>(?<:?F?H$-EA<:.B*""D:
@r1292
ACGTTNATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGATTG
+
.:=8>GB'95%6!/8F37:*65$43<%2!,<0B/@=B4*'=D3AC@(8,:$G;>H/G="3F$.6G,,4+1:;+CC<%5099E3B?7'))*:!!"2@5)*;>!--E=(FE&0'.C*/6<(@-?FA<$(H9>
@r1293
CAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATG
+
-F@0-#4+6!*:7=:G&B'@3<<3.)%'<DC=,HH*'C(-;@'A"#!+<$'A=
@r1294
AGATTATTTTCATAAAGNTTTTCTAATTTAACCTTTGTCAGGTTACCAACTNCTAAGGTTGTANGCTCAAGAGGGTGTGTTCTGTCGTAGGTAAATAAC
+
"*+*%)'$#%+!&"%'$*#)&*&&%(!*!)+*("!"'%%#%$$#%&*'$&#&(#"($*+&'&+(!'&%*$')")$%)&"%++%'&)*(**"'%'%!()&
@r1295
AAATGCAATCCCGAAACAGTTCNCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCAT
+
H3<A:'989'H89<DG+#-)6F(=1A'80B6C7#/(?.:8D:'AC860+/:'>#8*:'?'HD::HE@>!H.";'24"?13))=!*.*8#1
@r1296
GACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCNTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAANNCACCAC
+
+(&*&$"+!)%&$&*!)%++!!((!)$)!'"$&%#(*$+*&%'$"*(+&'("++*#+&*")$&"'++#++**!%%+%()&"#%
@r1297
GTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGNCGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTA
+
?2D4E(:!40-G90G&.A$*-91'A68+(E!8E3+<6)*47&((67D8#=6/(G6*77<(4*2(=2F5@=*<5>DG2>4.*+A3)B0+=F0G"7>9((3
@r1298
TAAGAAGATAGCAGTGATGTCAAACAACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTNTAGTGAATGTCTGTTATGAGCGANGAGCGGAAGTTAACACGTA
+
D!C";?:)<(/9(6GCEBE3=62=2#,6=6D7B8;8?(%%74#*9A)2H/7D0D?*(.5B!!1"%6>13&#%"&+$#&?=B;=DH#;5.$E+DH#@74GG1:+0.'2"G*7E!$#H!!C@,<G#;<-/E0C>9%E*
@r1299
AAGTTTTGGNTAGGCTGATTTGTCAAACGCCTGCCCCTGCATNAGGACGTAGCCAGACGGAACGANATCTGAGGGCCACGGGATCGGCGCACCTGCCNGAACGGCCGAA
+
%1AA8#+(D'9>>7>*@E/!38)9:&2:"B+78#F8A=*!(CH-$C462'*$1B'-AAC.G1C6B,3H9;'41::G@F7<"=CE5";8(('/>AGH2D6A'-7#:8%4(
@r1300
NCTGNTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGNTGG
+
$7<DA3'*F5::GA2>?7/6>@1C%>%?/9$B/>E?6,572!:%AB.H!=?6910#17>.;70"F42C,")2#.<3>G;/6995<;4:1GA7%3'7;)4=!,4*.A%(5>"+5'5H,%F81.9A6:3G$"<9/CD+.8:*55%HE.$974$%
@r1301
CCGGTACATGGTTGANACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGAC
+
1BB+(%)!$2%1@FD3/@8#?6*1#CH'+DG!C9:A;@3($=,7B,(/D$:E'/!)>4'+,CB=8(3A%<.+.$7+;@'#+&B?/C%2(&2,"(95!F,E"#('B$8?"+);A&#26@B0EE&>F,/;(G8H.262%B2B-'/FC(8'-HC#4,&%9.08B
@r1302
ACTTGAAACGCTTCTTCNGAAGCCTGAAGAGCTNATCGTTCGGCGATACTATATATGCATTAATAGACTATAT
+
5:#CG!=-)%-#7@8.D0&-)?7<&<34(B27'5).!616")C!*@,%<@D#'&&%67#?B12+-:$5%76>4
@r1303
CACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATCCCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCCCGTATCTGCTGGNATACTGGCGG
+
EA<A>+E18;H0C6",&EB".B8,=E(('-B*86-./%>*(.%D-+D8?/?1D5+85'+%0.;G0?:9,""*G%%"H=*:H"5/*'2:C(!@=-.1<BGH??/%@H74D7)18%2
@r1304
TAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTNCATACAGAAAGATTTGAAGTNATATTTTAACCG
+
<>7A4:$6/$,-(=;),-200<DG231<*$:9H>$:3D/8C,C4/>*;+05F.7"+H5*;!G;%0.6(/*F%0"52;-B)HA"&B:3#&%E"(6/?G=3"C@:G,6G?8+4$/E=F-3E6'7G:-/H(+
@r1305
GTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTANGACAAAGAAATTCTGGCTAAAGCTCNTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAANTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCG
+
H66";%-5;+,A?"02@9@A6&?;%A*HH:69D4.H%4*G9;2?F-3)2A8&G"=-#1,1;A,6=BF?8B@F#73B?%@(1#<.=,0B3&4C.-@$8-HG$D0<912!@!>A#)E$'6!%19%@*$/;!>E3$#D(G=<16E8,,4BCD+(>677!6'DD)*=;>'-);61$;,+'329?,">3(.(+6"A<H:7$0F.-)C;,
@r1306
TCCGGGAAAGCTGCTCTTACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCNTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGNACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTT
+
>1();E#".G5C@(#;()44!H'E#G$F+3$0),<8<#)!G64-*'*F'&)*99.C,D9A"A-995C)F"C",#-C2C"4""7%B9*38>!@%.6->!BD0.,%&*./%!<:E/1-+2.><D3"?)?>7<":*>A)$<.G:AA0).(!GAH"+0+:@0*=?E-29),D1;,')+*2AGB#H&+$(G"G!0+7<;#=59E?6,A@%=8!44C0)%
@r1307
GACTGCCCCATCCCCANCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGG
+
4A(><?6:F$(B9")4B>.E2.9+#1&?0@$/:+'/#-:"%*%8GGD42&G0>>D+)(4!1CF.:-/,$6#4>'%6B.(A$GGDC/=7A4F+&(='&3""BD/F'3*E*./#5&:4)5=-B/E"-06GB3'53(!>=0D-?B0'2.H$;!@(@CA;&.=/G
@r1308
TGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACT
+
F6A4&A7.@(E=7G0*G-1,DE&H<'#'A:,:@0"94!6A9H!;:';=@G
@r1309
TNGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCNGGGTTCGGAAGTGAA
+
)!*+B?)6F.:/1??6+!+8*E<26E'H%EDE*F$+'FC*)2""248*<AEC+$/)+'8:*1)9?;*+83&4(7*9C<D)C%$,)(A,
@r1310
AGCAGCGTGAGTATTACGAAGGTGTNATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAG
+
8586#4=@,+;+.CH("&&?8@-.F(,F10;526A005;?:#$<(+(%>AH;072HF'8C'6BHH$*>@&F>>G!7:&"(4>G<54H-,)%A
@r1311
CGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAG
+
='/A@@D2-<?,&+?G<@%00/+>&&'2EC-'!A,9"2.+./5E$=6-E=,(%&=.2&7/FD!,A
@r1312
ATTGGGGCCNGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAAC
+
6(>(6:@2;(F>!5?FEB=$&1@@(:5/17=GC:>7@A5'*%*<F=H#69HD.;"&4</*C:3$F9F2B@GC(,8H>&E"A&-@/$0D2)9',2(
@r1313
TCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAA
+
18)-@<<'4G1/D@>G>FD7'F8)4&'/=G/#9D6#9(:'%<F#(@E/
@r1314
ACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTNTAACAGAACATTATCTATCAGAAAAAGGCCATCTCNNAGCGCCTCTGAACAAGGTCATCAATGCTGAGATAGCTGAANAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAA
+
E%1):0G3@4'(/">H$%%<+<D!9$0E4"*>5.)38E6?8B1H),F%)D<$:)>)DF*&3+H%$B5@'(.;,":*40+ADH5F%B!67*<(G23$8G.7<(H@"7(!0>+("@9!6C'07E9,41,5/@,B3+F?*)*-6#)G0-46!+6"B%<D1FB8@CA=A8>2:
@r1315
ACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTG
+
7G>:F&.1;E"F>DA>8+?""E7$'?$@>CEC<")'/):1CAAF3H?'C7-
@r1316
AAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATNACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCG
+
FD-,(2<96:79>,9A%=*.!;(3!;-9%%E<62;0-%"90!)&9&3C37@1.'F-30":1B<2,;6/&#9&C0B;&1,&#6.A%C?4?AG?3BH@>&?$$8A>%@)"67/-1B0:/1A
@r1317
NCAACTGGTTGGNTNNGNAGCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCGGCCAGTC
+
&&**'!$#"&'("("')&''*'$+&)$&)')%%$##)(!$(!++!$''&%"%+($*&*+"'"
@r1318
CCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTG
+
5*42F3:<F$:.=,.+0##->0#3*#*A9,':*:'E2H/2A=E:
@r1319
AATCTGCTGNCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATAAATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACC
+
?C>76E%@0,A,4/E#)!,9H*7<66G@,0093:'6D,.A146,$4;#3%)<8FC6#&46F>:-ECFH),-&0D401#.#F%36
@r1320
TTGGCAATATCAACCGCACGGCCTGTACCANGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCGTTGCCANACCACGGTATTTCCCCGATACCTTGT
+
,"2%6,?25FC-9G1:+HA,(;-E%)9<=BB1&+/%2F?@)#,'9E>46./%:@7:2(#%C:AA/0E4!F06&#9>5+;E*B<?AH.H$9=>A19</&+D!$%*H+'@(*>>>9)78#*0-:/0/>7;+E7&.(=E72#<9>H5<#*(4@A6<75>E+AA>87=?+<B.+:8
@r1321
ACCAATAAAAAACGCNCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATNATGACAAATACAGCAAAAATACTCAACTNCGGCAGNGGTAACTTTGCCGGACAGGAGCGTAATGTGGNAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTNAGGCTTATTCGGGCGCANATCTGA
+
5H6AE2*:0$7+190&?.7";!0?":9&G;)/=!8//*-@???F&EG=2,B+D2(*-E2G,/(=$8:0*).=C'*"1A5/".:?A",)/A92(#8291333>@>9,9G5%"$@5$$&49.!2-517)'963'/3@+9;:-C>4A96-?88C;G.,4="B/4H*72;H+?E*@>!?7*9)$32EA3H-'0882%A0+6.;-.%%4#E)=F+>')5!):)B,D,+%4=D@
@r1322
NGGAGGCTATTTCCGTATGTCGCNGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGC
+
!+!!*($*$&#"$+&!"(%"&+&&"&(##")#%)$$)'&#+'*()$)%'+*(+#$&'+&#*"#)*%
@r1323
GTCCTNGAACTGCTGGATGAANGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGGGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAANGTGTTATCTCGGATGGGAGTAAGCGTATTNCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAA
+
!*!%)#+'")!#+&"*#&)$$*$*(+)('*$#(*$$*+*+#**"!+*%$!+"++"&"'(&%($%!+$$*+))"*#!+&"%'&%))%$)'!!*'"%#!'%"+"#"+&#&%!)*'!)"$$++&%(#")%'$&(+++#')#"#$#)$%"&&)"+%'(!%(!("%*)'%&$)#&%%%(""'$%(!%'(&"&'+*(!#$'"*("+')*!'+#$$$("(&&#++''$
@r1324
GNCTCTGGNAANCNTGTGAAGACGACGCGAAAATCAGCATTTTCACAAGCGTTATCTT
+
*"*'$'$&%)"""%+"&+'+$'#%'($'%''"'$&%)')"$$"++!+)%)!!"'!$*"
@r1325
CGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCG
+
@7@E-:7&G)D$9%>9.$'++GC':G;(H):*0!CC1&?;G2F7*4&/
@r1326
ATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATT
+
;#:A<#"?0;&@8+-"EA*3:0390$F6=9AC)/03&*%?>F';+%%-#4
@r1327
AGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTGTGAAGGCTCCGGCAG
+
>>B*B(F;'.-B#&9+1(8-(/2H&3C.,7BE#<3H/7:79$>F&$B'D-5>DG=&!!*1&4E88A'GCH>,%&5*2/&/7&1ED8E>=)36A@@H&%@!-+A>9;4?:%=0G;B<GD.E?88H'8D731<5G:25B*7%@"(8!88:,=;<$E6<+3;&/6:3=3%+46
@r1328
NCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGNT
+
%3=F/B6%3HH0C3H'AB*91?!6!/00B#(@C;,:+&133A'.7&0C4G64@15-C<)F%'1G#*F5G;C'4*&2?,@(><GG:G3,9%F
@r1329
TNCCCCATCNCCANCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTCCATAAATTGCTTTAAGGCGAC
+
%&#(*"+!$&'%$'#(')#&&#$))!!*!%%(+"'"&#$'&')$%'&*(&$+)#+!%$"("(%#+')(+$(+)&""(#&$"#"+!
@r1330
TTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGT
+
;$4F(F'"%AD<%G&;$=?":D=&8>64D90$$>G'?;<@*$.45FBB4+);$9/%*G&0'+'G'7.G:'9.#=%4B$D1&&3;G#$B*:H0'H6>*'!ED!H9)D<0!@.!E*<#%*47%E4:@C*;>E3CG-E+;H/'*-.<)8@A(!-<@2*'46%049!?3
@r1331
GCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGG
+
B<.B@H&A8;+3&<F.(G"5<G98,-BF<?<9F=!="9+>)",
@r1332
CGGAAAAAGAGACGCAGAAACAGCGGATCANACTTAAATTTCTGCTCATTTGCCGCCAGCACTTGGGCGGTTGCGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAA
+
$6?B'-5'D5=8#::="E:5F?@D#:%>'6*385./AE(0=(F0(+G)8+?6+:0<'>#!C7,8&G7(@C0>0G?16-%79#.$1-9E;G2)C*;5&*"F**41D1#4G9$"2B*:+@&+;%"*(AE*D)*>.,E5F0<8
@r1333
AGAAACCTAACATTGATTCAGGTACAGGCAGAAGGCACATGA
+
"-A)>"6G+)D(65)?):(G2)57>H>E5-$:'-#3%6*%?'
@r1334
TTTTTCANAAGNAGCANTAAGGCGACGTGCGTCCTCAAGCT
+
()'&#&))(&&$!%)"%+&+)!%)'))'*!"!#)(+)!$!(
@r1335
AATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGNCTTGGCTTTATCTCAATATTATATGGATA
+
;;2(4CG80<A,*3%D2$$H7+=$*6&#$%=0@1A1,,><#+6)F58@(@BG",.&HG$8?GB9-#7H0B(B//0$0@*4,;H,9':>D!,;;!A<;0E)/#B,$8:.2+B3)+6C81(-5G.&C0F'+C"+(9/5:0/("9F:F?C<4?3!)4"FG)4/@@D):(E/<E/2,.E0H.E#B*>5*.0;6B:3%&DG60A$!A:,4@%*$#A%'5*D@3/'"!%6G:2#1)6!80+
@r1336
CTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATANAA
+
*,1.<@-(BC*$%-E7)%<9(8,".A%3BF/4)17E:H%5.:;-
@r1337
TAGTCAACNCGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAA
+
>E2/:-E%$&6)B@%6;6;!E>+.%?H9<0=BE72DD>?226E#,>0/9,E%CE1@#%+??>,3+D)A?D41
@r1338
TNGANNCNNCGGNAGGATCCACANTACCCTANNNTNNNNNANCATAACCNTCCNCGCNNTTNNGANNNNNNANNNGNGANGNNNGAGTNGNACCGCNNNGNCGTNGCATTNNNAGNCANNANNTANANGACCNNTTGNTNNNGCGNNTTANCTCGNNATGNGGACCNNNCCGANNCACNTNGGACGNGANCANNTGGNNTCNNNTNCNNTGGCNNNNNGAC
+
$$!!#!!!$$$!!!!!#$#"!"$$$"!!$!$!!"$"$!!!$"#$!#""$"!#!"#"$!$#"$$"$!#$"!!"#""""!!#!!!#!#"$$#"#$###!$$"###!!$$##$"#"!""$#!$"$""$"#!!#$"$"$"!!$!""#""!!""$!!!$"#!##"$!$#$$!"###$$!"#"#"$$"$"$#!####"$"$$$!!#"$!#$!$"###$$##!!$!##
@r1339
GCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCA
+
.G#52=)3C.(90;?C#%,2//B1*098.-;77(E$6,<1;11)@5@(!?8%29?*-
@r1340
CAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAG
+
4/@.?E8+D/@<<DH6*H$$'.,:/&%:!1CC)0&&C6D'<2F910+3"=6#;4++((7G,H<1E<;A/E/(=8'>GDA/=8#!'E'/$'/'G!"%'%?;"2#?0)>G!,(@<D3,=F0$0)A?+/@5?,7G=$"?:-3!/@,7AC:#83:."G,:8*.@).E:-G%!9?A$0)G,;<:G.H*=$A8E6=%:)/0&+4)7.>+'/9!?B1G70(&;"")9*"/9B9+7'B:@;G;%6:3&
@r1341
ACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAG
+
?!?3H+<&>*C6G0?4D;7>4;1',"#5A:>GC?:!$.=7@2B/12!5?'CF!HH@5'"7$#87E5'A<??&%=
@r1342
ACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTNTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTG
+
G?+>?''2?1"*$D8>+.-&4)*).$;;-.&.2>#9B""#+#B&+33H4'$(5&3<!A<3(4H$/7';*?C3(B<H>7A--G<%%;@#E:>F?<H+H1>#D?H==>#!-2B-;:!+E6:)(;<;,8>*205$7HC-
@r1343
AAGAGCACTGGCTNACCNGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGATGTGCAGATATAAANAATCCCGAAACCGTT
+
)11D1#!9+?*EB#@5#.-%"E+0:@D7;;H0#C6AC7;C"?)2A$1-#;BGD'!<8*AB792@-3#)-,H*/?'F7=>,:&#<H62,2%2A1
@r1344
GAAATCTNCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCNGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCG
+
@C/8D!!-9+2:EF,(65@C$)1*+1$E:-4)#38$H?!-F.GH;7,@5F)5(*?H-7$(B0?<8=,7.G&2GHCE.*.E#F24A*:"%7%34>/?/@5)=9%B>=>1D-@AF8?<@,
@r1345
GTGGTGATGGGTAANCTGCCGCCGCGCCCGTTTAATATCCGGA
+
'D+DA50>"(#DGD=7.'<%'G4?D1H);EF)DB/B)!C#=:9
@r1346
CGGCGATTCTATATATGCATTAATAGACTATATCGTTGGTATAAACA
+
9:?!$14!0>:)#)(9;3)6*A8:58;B.<E0*B)9$%?52A"@5*-
@r1347
GCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAAC
+
9(-17!">FA"9G-'>.1,!?,(:,%B$=#)?5/H7$("?D3/)H+A;)AGG>7-A=)!>'4;:2/:#%G>8F><8H,?#"'&8B04<6#$&F>+1@'1$?>'.3()E5CCH3H+3>-3"3?16,(@/67E#'%H%>$$:@81E06")B@*@;5?+#>BCG82!.0G03@+"+58H.7$%2*@4?-GG.8F60$7=A<&29>?C.,,"=:;-*9+,31H6,1D397>"%:C+80')C:,51=/D=C81B"?(/B#DH%,F#*17G!-.>D>/=0-5;G
@r1348
ANANTCANTANTTTTCGNCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGNATTTATCNTCGT
+
("(%)#!&#("&!%$""%+$*"$))!)('(%#'#'*&+")&!&!!(+"*)%*%!()#)")$$$%'$!+"!**$%+"(')"%(###"##+)*&'!"')'#)*"(!+#'')$*+*)*#)$&"$$&((&$)"#!$
@r1349
TTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGANGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGA
+
329?0F;&GH9:?5(H.7=37&#"%8)G(#"&,!/!CB/0BA)0-C&2&:.1%EEG#0?":3C-)6&+*991DC;4'/.&.<3$602;C7"DB+@*;7;1CA#H+95C4F,,:)FBB''&1C3*F5(E+81AH$+;,57&)3:H7#)&!1
@r1350
TAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTG
+
4*+C<H'$;C'0D#;64?@78H!=:3?C,2:54,C)-0.%C97C!(268'0,0F2$(5#?F3(!)A2;<0@+>>;G=0=F,5DE>!$;'7
@r1351
NNGCTTNGNACNTCCCTGCCTGAACATGAGAAAAAACANGGTACTCATACTNACTTCTA
+
#!$"($!("*)#+""!$(&*$'+#&$$%*!'("+$")!!"")++%'*&+)##!+&"%#'
@r1352
GCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGANAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAG
+
14;=7B!0+28DBA%9!AHC17%('"!'0%!@?6(*>@=<"?96,E;D1"H:F@+.=0<-*+0:+%@8$*<-GF55'3(E;$>521HE,B:A<@A6=!"<:'7-0@"2@-.1+66,?%;,5?'@"=8,&G$?878"H*'"715-A/
@r1353
GAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACC
+
;?"4+$D!78+<,*=$;1$+E+G<F3#=!0#5.$)>=78'!67>2E%?6C68#<><-+:)<*6D0=**4(-GF0&;+6
@r1354
TTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGAT
+
G,E<'+H7'F0&@;$28H.A2F/?:B0&"2:/3!3+;>E>)>.B@<83<$(.4/&84@.(.:1C$GD,6*!F<8
@r1355
TCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTATGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACNACCTCCTNAGTACATGCA
+
G"#B.FH/!3@!?*BHBE*,(%'(=#=?(+=1B572B8/37A;C,78*#BG2GB79;='D:95?G.4:=!67#BBH?"#,1?3+HF!/88%0-AFB+2+7!4H<3574/'?*C8)H6+"3C;6D29<&0;=53E#H'6"0#:@&)B;%->D/(+*4G*G89;<C:%*%&!.A+-1#;C=
@r1356
GGAANGCACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTANCATTCAGAACTGGCAGGAACANGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTC
+
100?=9:#02&"@)#(-C<D</;G12)6)*!='<H92=2</F2*A($9$=8!!<<78430>-2="=>-@@5;@H&*0@E<@-.#(1';"+1+)H5";78=@9/05><.#97:#D/(&.H&"-=+#(=H>F7"=?,9F%
@r1357
GAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTNCGCGTGCGCAG
+
:05'%(A753DF13139*D7)(*"'&#F/*1')F29&:=)H$H1$'ECF4:,F:!-9/A!1@1E@/.0,>#%."'CF,
@r1358
GCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAATCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGNTCATTCGCCCTCCTGAGAGACGGGATTTAC
+
B-A%%+CEG%7$DD-,6)+>;*F($8-7B4)83!),4FC:-&!5E76-8)+(**;#&?DH>30.@3:C,*A7,2:.C"',F%>%D$D&7>&&#3E*87"=/67<?0*8=''9B2#*E$;*5260&>>./2H6"*$6?19.9>E.+FB&?+63/E$=:2)?
@r1359
GCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCT
+
.;6,''@+);D(1&34<@:%C2)>A0;0*8,+,/=*CE%A:C70'56=!#4G/9+H5.!
@r1360
CNCANTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTTCTCGACATAAAGATANCCATCTACGATATCAGACCACTTCATT
+
"##*&+*)#!%)&"&++!#!$$"$(%$#$+&%#*%$"#(&$&*&$)($#!'!##&&&")"+%)*(+'+#)&%&"$+#!&%"(*&))&!)++'%#%$*!)#!#*"&*%)''+(*+*)(#)"#+$&&!*#&&(&))
@r1361
CCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTNCTGCTGGATATNCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTC
+
E@8;809/5*2"##6#G2!7GCAG*D):7?31A<.?D4>2$/??8F*15BC'A:9';::216?&F0.$70B#@4!)H.64<G.<(290>$<.'44#%,?.%>1,GE=!E%6<2@>18.#E%C<(B&/)G>&;'"F)'8&F@)/.8G*#EB.AC!-8AA#.$4;9=$3A'?6-!
@r1362
CCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACGGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAA
+
18299)A!!E&H'#9&82-7*7A/50GB5(7'GBE(23#>->>83"0'"8C2@E?,G)C67H3,!/)(H@2$F/D4D@+6&*7*H:;*75+FA6+!,D=()#F"H7&03+20A*/"7F*?#9+D,$'30.1&&55H(E676>0B>'0<+67<#%<7A'$310*"#>;!<&97C!6!>8>1/'C/@B';,/F3('"F#3+)",E!!)2G'"&F5#-E*?@534+B&H+F47DF9
@r1363
GTTGGCTGACGCCGCCTTGTCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTC
+
&<F,D;@4GBC"A!3'%41"%FH.0!+1<$F@#,?9"674:,/6F1;5A3B!H>,%7+$$'=A::F&.%81)
@r1364
GCAGTCCNCAGNCAGGACACGACCACCGNTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGG
+
)*!''"*&""$)*)*#+&*'&$"#%&"+#"%''!'!#&)"*$(+'!''%*#()"''$#)(("((&!)+%&$#(+"&$!
@r1365
NGGAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACG
+
"%!33',*?28*!780B)=-ED;:89*'9=:B'"/-//-#3*3$/,05FE.C41=@:32,
@r1366
CGTGCAGCCAGTGAATCCCCGAATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGC
+
/<A.,6,:8C!H1+5"A<)60-04:-=767D$#2?;5%,E0E-*$#A+7**6/!A<E=$+1-=/03=D"0F5:(=+,=5=?:8;
@r1367
ATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTCTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTAT
+
@:D95>%26+.#$'#!);%@B>(>?"AH,1B!A(D.+5C?$&.2E52/>GG:)@/:&F(HH/E<F&=/.C/5-0(%C*4D*<7DF%?0DG93<+'>3@E?663*+(B@F;,==/'+8?68%')
@r1368
TTNATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTGAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCATTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAA
+
;+'?8B1<>=*9.A%/2)<#C.?**,%F$=09<8,6"B!"EC8.?%0-21H-1$5AC9?H4&!'85B!$F9G/1C4GA.,H=A;$3E7847!+6.#6;@<<!2+0/DC=>!+D3(?D#F51#/&D(;"H&!4->5$.(0:H(9;.'7GG&70>>+*6"/C:""72";2!$B"4"F8.*<@)5@$(4,14#%D'&*?#*!*ABGA(?1"@"!F!'9B)D;3-5
@r1369
GNNCTTGCCGCAGCGCTCGGGAANGATCCAGATTTTGCTACCACCATGANTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGA
+
)"#'"&'+%*')&++$*&%'"+#!%"(+%#')%((%*"%(%%)!%!#)'#&*"%++'*(+$%&(()%!*'%)($())&($$(*'#
@r1370
NTGGTGATGCCNGATGATGGCGCGGCGTTCCGCTACAGCTTCNGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTG
+
$5:0=B,/9$,,=9.:FB"=E*E#9-E&2;74D(/?AH;/G;)#50<D;65C:&5%?E4A(-F(5?%0E@D/;E!=?2#0**?H*6'$
@r1371
CGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATNATGCCAGCGTCGCGAGTGCCTCCGGGGCAGTCAGGCTGTCGCCGGACACTGCATCCGTCAGGCTGC
+
+2H6HDC.$*&/"0,G/43>9/*>E&;E#+7+*<$),8=56,7%-21#?-5@D(/861%&(+1"0#!6C&$!B(G%#;<3;C40*3?;'E(2CBD(%!H$<&3/=@0A3$G&&">+D8>D,@:6>B/$,#5FCEHHE4GE)2.3;F5,#5B!*C,3%,3E->)?$$
@r1372
ATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGNTGCCGGGACCACCCCGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTNCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGNTGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCG
+
+B=<9BF*%:AD4+(H9DGD;H%0"0>("?%0D2-B5$C>!25+8)=5;H'HG>88:*ED/&>*FB32-<<<9)D#=*.4?E"C7B>-#!>H%+39E2>-!&;G287#A7;"2;G*+3<@;4'D.3)2D9CFB=E945:;&"9*!@119%4$4.E=7F0&<($+9D.=22#,'(*"$%>#-%*@<E1H/,D4/9H8-9E=7#7*/$B264/1DA@1;(=?*!*G*0>(C!&'!4('8A1</#E.E>F4H0G>$CB*%+7")?;,C22&;<68A5;D@0D3'>GH/+(#(="+1=.1,9?".'4G8A$>:!;)"=);A:4:E'.
@r1373
ATTCATATATGCATCCTTGTTTTNCAACTATATAATTTGACCAGAGAACAAG
+
'0,&<G6ED="/6:=?200.?>E7>B*,-;C!%C::E,DB&#*B!1+!/:"C
@r1374
GNGGNNNAANCTNNNNGNACTAGCNANNNNNCNNCTGNNNNGNGCNACAANAANNGNTTTCACCAGCNGNAGNTNTNNNTNNNNGN
+
"""$##!"$#$!!#"!$!#!#!##!!!#"!"#!"$""!"!$"#!#$""$$"#""$!"#"#$$#$"#"!#!$#!$$#$#!#!$!#$"
@r1375
TGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACATTCGCAAATGGATTGCT
+
;2B=..>)C@()3&8:D+%B7G?,DF+->':E0D)3(#'$=C%%90C'66C3=("13)D%H5H0>-5<6>C4<.FH!E#%?
@r1376
CTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACANGTGCAGTTCCAGCACATGCAGCTTCTGACCGCAGTTA
+
+#(&%$&*%##*)$+$$'&!$%*#+*%"!*!#)%""*+((')"(+)%*!"$+%$$)'!&$$%"(!&"&$)!&!&++))$+"
@r1377
ATATGACGGGCAAAGAGGCAATTATTCATTACCNGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACNGGCTTGCTACCAGGGAAGAA
+
+!"!*"$'%!#$%+")!#*+#""(&'+$#+)%&($'!&+*'))$$#!()+%'#&)*$(('****"#&'#())%**"#"'"**++*%%)&*!%"#&"&*!'%#((#'%)!'!'"$#('$)%))()!"$#+(+)#%#'+$)!'(*'(')(!#%*$'#')'"&!)'$*%*""'+*&$&)*)"+&"#%%++$&!*!#$$$'
@r1378
AACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGA
+
+-!D2@76./3<@6H+-!4:1>3&%:(3E<3E+'>=32%2&?@/9/"#$G=&+5H9D2$2.,9</?"&)G=$6C%,$7CH!=*A<B"A?C!E'%3-->>.E(:5.<%%<,A#@(>.%2<G$H$<0@G*5+%(E*CF2=8*$.@D3:D*#5?G,/&H@=-.:1
@r1379
ATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGA
+
&4;+(8:#31'!C.88C9/5,79"),?!:976=A!8B#!!/DH)/!DH42&17A5:("D32406;D67:.C4>B7HE!-/%G4H=<2+F8(((!D5"+%15$-E>;C7E84#2"1<GB#.=F+-+62*6#$7".13;H4'*13(7!6B4C?><AF)FG=F!$$FF1CA&!!:3H'$3$.(G<1
@r1380
GTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCA
+
@=,;6FHC7&.8</9E*1"4D?+',?-0:$D/0H)H75GA/1+C1*$CC=;;.-04,#@"*D7<<E(:0
@r1381
TAAATTCTCTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGAT
+
6%##"#G2!/6$'.(9)(G.98A5'9-8<,<D#EF=AB8.(9'!3).A$8-4%62CB#,&B$2*8FBC127)&C8F3'?BF;C)B8@&2;&(!/F
@r1382
NTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATANAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAANGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGA
+
+?>(1%BD3"A7>>,*=6!;8#8%8-G<2>-=0'74?HH#;C::<-?1?.$9A>-8*:37373#@254=9!:6H7>E0?9?%'FD:#<=$DE/58DC0+1:D1@F:/2H<*;(FH,<&AE'D9%16G;.F%E?",$=E./#.(+4=2#-:E4<G33>BE@74G5'*C7,26$%>10"EGC48E908#GDA;&<4*-4F;>:H
@r1383
NCNGAACGGCAATCAGCATCGTTTAACTTTNCCCTTCATCACTNAAGGCCGCCTGTGCGGCTN
+
"*#+&"('#!#&"+*+"'$'(&&(&#!*%*)")*(%)(+(+*"%*++(%#'")!&')*+*##(
@r1384
ACCGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTG
+
6!G&!A*!<3#B5*01,)51H@G:;-E'CA1B)+:3-C?.EH3#E:0CE%C4&;:'?5)%'76!4$!BGA:<";!(+"C44(47@,)
@r1385
TGNNNTNCNAGNGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTANCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTAT
+
"'")&$'&!&'+%$'#&+'#!%)#+$*$&("$"#$!#$%+&$$(#$""&(!*($+*"((%"(")"!"!#))%#&+($+)!#)**&*!!!&+)#$%+$%&(#"&"&"+#(%!%''&)$+&!++&
@r1386
ACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGAT
+
3$07C6,3$%1./?+H01B!-?3<0+<D/>)&6=/!1>&4*'1$/>
@r1387
AGCCGCGCCNGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCNAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCAGCCGTTGGCATTCTTGCGGT
+
@?&H>/"<'6H3)B>:>7A:!=@=B/<H=2'5@&A60AB/4)D,AB9D7675G=(8B71+@1</+B3=6HB#E(?=#F.<#*8?''H$E4"B>-=:11@6G+/26B99FDA<&!996<;<%#E7C@
@r1388
AGTNNNCNANAACAGTAANTGNNGNNANGATATNCGCCATTATCG
+
!%(##*($'"&)*(()(*&"*"#(#!%('(%#&$(#+(&"&($)#
@r1389
CATCGGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCNGTGCCAGTCGGCATACTCCGTGGATGAGATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCATCGAACACTTTCCCGCAGNAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCACTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCNATCTGTTTAACGGCTTCATTCTTGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCNACCAGAAACNCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTAACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTNAGGAACATCGCTGACTCTCCGGATTAACTGGCNGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATNACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTNACGGTGATGNTCATACCACTGACCGACACGGT
+
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
@r1390
ATCTCTGGCNTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATTTATGGCCATA
+
7?F>;,D.!70*>G:3)HA?HA2C(6D0"&1=-%8?4=C($*@/?>@D(@;#?%'E#0(E>+6C;5$#/1
@r1391
TGCGTATGTTGCTCAGCTGCAGCGTTCCGGCNATGAAGCCGGGGCATTGCAGGC
+
8C41-)!81%.F54%<))<2+.+1@%HC2?H9,A'7G(--1A.E;C2E,@$#2&
@r1392
TTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATT
+
>14E:/D*<@@1?+@C,E&1&8C13B)D73>*G.-C/0)DF,6%828')2+H-.72?#A103!:,.170C1"(6608G8
@r1393
CCAGGANTGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGA
+
><DF!55=?$4'@.'G.B5.DA861;@%*F)/!D<0(?!,)?@$1#::0'$<5<'+>C/94B)<C98CH0H/,$5+>?<,,5
@r1394
GATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGANTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTT
+
H)4&5?.H=B?3=%%E73%06&)@*<G#+.)H);%2G$9(4.4>C.8>A8D(149'4G/6H/==G/@!.%#%'9!'?"C>D?*=$C#C;8**2(B!0(83>2#,CD006)3$+2+890G"7A/
@r1395
AAAAAATAAGGCATTCCNACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTNAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGTCCATGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTNAGTAGTATGGCCAAATCGATTAGCCGANATTGAAAATGAAAGCGTCCTTAACACCTC
+
*(F!G!(33;=E/(7%4(F6*7HD:5B<6498$;)2+)$?5*;9$$*;-=.>)0)HE,=4#.4<=.A5/?CCH46*4@19*G2&=?0!+&+66">9=(H')04%%0E;:$2&;5BE>-%;F81C9E*DD7F#',()FC1#6!)%>A:#)4!:G39=*9%E3<0/(G91-$.+()7@';E(8/@D#&#+5?.8:"7C+&;)**4/1CF,4@%!4,>.:)7<>??9@2E3-.GH$<!$&8#%&9-+C;-HH+15??947*F/9G="AF:3)*&-G%B>A41@H%G)72/E@1F,/-.DG??,90?<2@&3$G8:6F/*-'HF-,H5!&5@$&@!8=:@2EF#+#B);)C)4GGA533#7"
@r1396
ACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTCAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTTCGCCTAGTTGGTCACTTCGACGTATCGCCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGNAACAGTTCGCAGGTAATAG
+
@F5*EA36&+4AD(;4?D>B<$F:'C$0H.B:.:>%3FF+>A/G'+0D=22D=D9-C!'C13:02D6$.1AA8B9?%/CG0)*(',)F.A?H7*=D7*+<DAF!6:<F43$#199'4!BH<&)F?C$8>.,$A.'35&3+$H,4&0<#G,>@!C*64H)9;403:("81(+.=+)G4-65+$H-0@(5$!:.DH&,(/'-(>#&"308>2@+<1B9+"GBA+#.B%=)HDG,ABA2?1%6B?6=%
@r1397
AGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGNGAATGGT
+
+'%)%)($%*!$**+)%$%&%&($&*+')+!%&!)%!+*+!+&$+'!&%%$'&()""*)(%&((!)*'&%$(*)('#
@r1398
TTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTNATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTNTACGAACATTAA
+
8%!&AG6)(-%@$+<"*?*:6/6)''1>F75.C:?>%3-9)C=86))F067#C"-A4?.(4%,D+80'5B30?<GA=@E>&<&0.%&1)BB8C*(+=-&.6E,E7%FD:A,1C;-C
@r1399
CCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCNGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCC
+
'@6(4;'>.F;!D',*6)95:.E?7*&C&!6//;1,.A#:@;5=(A5E25E>H5(E.8,0*439!4$#'FE#+=EG'@!7?'F:+H@=@@@8<F=G;A(+@7<F'3>*DD"),&A)'(;?E6D/?&G<!<=(3%6&"'4(5$B.1F/5:=(#)#0)'D#5@.B>G-09;169+G,?:="0@<)2F!#'*6.@,'E0=D@G<*'7*&C4-B69".;A0;&1;>'
@r1400
AGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGAT
+
-B!19F'"FH>-B>9.>-&)!H0<--?6)A.*/#G,8-0.E=B#+9;&
@r1401
CGNATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACAC
+
*)"+#!$$$()+$&(""*+'"++($)('!)))$%$%)()**$($!%*(#%*"+!"&""#)!**(%+#%)%&!&"!**""!($!$%#%$'&+'*)&#&+&#!)#*)'$+*"*&!"#*)+$*"$##$'!+!#&"%('"&#&$*#&!#
@r1402
GGAAACACTGCCCTTGCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTNTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATA
+
D*$)#7*8)2&?26",A/G%?70",#G>@(?&>*!!9'8->.$F640H:5H)/=:(1?/2"B<8#"4=94'%AE8,:72<6)'6?+?1664/1E%*9C,<3>'>E4*2A+F<B82=B#=%C1D&F'-572"G%F6>:
@r1403
GAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGANCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGAT
+
C#%6=AD.5%)G1C+@(<2;=,H:!##8H$1+);%3/E9/$%6D6D;?<.#)-/*"HH(9!:!;=#/!&A$7#CC>-/(H,HBF)#:8E+,$$1<8>HH734.5FFH>.7C*B><?)4D*+>(!'987EA<+44#/
@r1404
TTTTTCAAANGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAA
+
<B6F,<G<8B+G>%C/;-<62%C64H98=23-=4;E'45H%4'%!.E'3<?H.6;-3E6F;''6C&G7"D@/)58&(%=6$#4*/;-66!=44F)3&+3@2
@r1405
AGTTTAATCATCTATATGNTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAA
+
,9.E-.4!.)5H@#+.@1*<0.=@AH3+CC$B.F<8FH2=D#5*.*=;FGH=1EGG<,9+)044A,7:BH-A8=5::0G<@%B/'A<(6(11G:;(C42@91<2#CC65=3E'BHG?:?&A;)59<?>)+'?+>
@r1406
NAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCC
+
!'H)4G!0F=766=80&(,+EE@>8:3D/$70&&'A1*G*@;"1?3>F.)HH11)A+@:7A)=D$%48/)<6D<.D7?'1@16
@r1407
AACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACC
+
,H=$DB.7.B&&2:E#?8.A;;*)2#43A(#C&0C?36D0;"2,(#1(.((!.F"%?1$$G0'/(2:F$/8!*=B=EAH;7<C5>9-D=A#BA5H7='@'F
@r1408
GNGNAGCTACNGGTGGAANCCACCTCAANGGGTGACNGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGANAATGTCGCCCCAAAACCATNTCTATGAGCTGAAA
+
*!$"(&!(&$')*+&("+!"$"#$"!'"+'+!*#+$'"''"$$)!#*($)&$'*'')(%)&$'#&!(&('$"$*&*%**#%%""""%($&'""$)#()'')*#"(+)$&'$&!&('(*#)"#$'&
@r1409
GGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGANGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCATACGC
+
/+'=;1<C(<%"56BE<(<":>%:#(;(;)+:&8(-AF4@+G)&<5,B$8H#8-2@29'+A=!#;4C)?3%=F+.7!E'$<?'><%7/<>3!3D:3>&3)2(/A"94EDH54G:+<3%A2<459;>5
@r1410
CCTTTTGGATNACCCACTGTTNTTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCATCAGGCTACTGAAGAAGCGTTTCAAGTGCTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCNTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTNTGACATCA
+
!+E&204/D1B12;&F/'D3;,H%'+8;*D.)#>D-H&41$;H7F?&%2,?.0/'!<#+5H7E,;<+B75-"&5A896<4<;&7)59'E;0@D@,:%50.=@&>!E*D(A&C*A92,5+C/F9*(D69!8'#6?;#96(!59;B7'8858AAD=)1%G6&#98&D-D(*63!21$C:.5#F)%3&C-(<#"65'D@.@@&B*9'!4?A$47@""+&;4'7$7A(,@@%84)E0C9!=,GB.A!C@$87;8;2+DG9H')D9BH4A+7G"D-E?&HH7$8'-=%?(:H?<&&F%BD
@r1411
NTCGTNGGTCNNGTGATNNGTCNACCTTNCNCGNCNTCTCCACT
+
''$%)"((#*$%(&!(##")&$(&$(!!!#!&*!'#!#+!*&*)
@r1412
TCGGATAACAGAAAGGCCGGGAAATACCGAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATCTTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCATCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTNCTTTTCATCCCGCTCAATCACGACATAATGAAGGCCTTCACGCTTCATACTCGGGTCATAGTTGGCAAAGTAC
+
:3CD"C+1@D1,9A%G6+C(%,<A'-'!'9%6H),,C"9*D4?>//8>0=>+H@(8$")!%DH!G@9@5":/*#G<D3G3,@("?G"F3"#B56/A,*0'1/E",@2(E'*35"*.=:===)'2<7*3=C*%;6>C*B*6;!B;1?9*-4(@B?H?7$$A>(DD=.38'-8E=E=6BG$<(3;*;GG&&=EH9FE2F8(BF,"/9"0;-04G%H?H$33H;;A)H.'FBA'?2)?617-=E/*5F4A1#-!779H:"7(7+>9?EB/
@r1413
GCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGCCTGC
+
8)*);=;0>;"#<C"6-D&83D8"A/D$8)@=@GFFB/8<@;%2!B2.C484,@"G'=&$?:+..:)<?)81164@+AGC7(1072:;7.D9:0<"+<5<#00($-
@r1414
TCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCG
+
=#E+;EE++.9,?,H:!*'%:H?-%D!6;<H(7.,B8C,4*;'
@r1415
CTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCG
+
'FC&8346#;$;)(%!4F.4)EE/'3-0)4H:=;!;"6A<8#)//9<F!3*<48<0':%-71G.F9.%4,D)5D/1=4AF01<;!3%$?=97*6A9(@$"'#A7?=-G0,;?87=8>@CG$6@1!=7=$+$<CF&2/;1+EA(%!')5/D?!;F-0.+&-,-:
@r1416
TTACTNCNCNTTANATTGCAAGAAAATGACATTGAGTTNATTACAAATGAAAGTATGTTAAACATT
+
)$"#(!"#!&+#'"*$&)(""*)&"$*)%"+$)!(''()'))&#+%'("$'!'$$!#!*%'&$##%
@r1417
TGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGNATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGC
+
A%!54DA!8A+</*?'.=2""HFAG!&CC(&58&.)>9C,@=B1193"*>7CA;AC*!8<<<AB>9(B/3"=03$!A)A-:5#'+(!&6'/
@r1418
GTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAA
+
3#=B.30G*4<EG91&C+$-.0+@.#8=F@-!#"-0G,-*AF>%5*;4*)@=5H9EHD,=58*!!C$#E32!/E+1@F63)B94.G<"8#E44&?""B/59"F+G.(.(2F54408B3@:6:&A&<4$;*=-8((G0->C88/5)C%@C:.>4
@r1419
GGTGTTTATGTAGAAGAAGGTATAGATATAGAGTCGGCATACAAATATTCNATGAAGGTTTATAAGTCTAATGAANACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCC
+
D#DD7+>311B",5?:!216&B7792AA.(1H'9#%F"&!A&0<';)G$"-B9E8<?D)2C:B"=+67D95#EF=+2G+=)8@A896$'F1&<B!;>;)=,H?=30*-3?G*7,+1%)?"1>%EB02"F&1F'D2&12G>-,+./:*6:1!,H><2G%$=8
@r1420
CAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTGTGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACNGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGC
+
">&)>-*G2-C"-0#&3$8*0H$7*?5@0,H(A46B/A>FB(01AG27+6+CH(4;F4<4>G=75@CG$%H0G!?A7E!?&3@"B%A:!&3!'?EH-2CDD#H9&A>!C)AD>8/@6G/=C$@C4#4C0#;9;@/9*<5D0-3"E%E+302-,5!<D$3.(8/:=&,#4;0>H.6
@r1421
CTTCAGGGCTTAATATTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGNAGA
+
>+9)(=0%@H<)9'@-F%7)74)5B&+>?26"6H3F@-=//.96,BE*3:<GC'6*556GE&:5A,>7/,*>=9F+6B/39@AD#D#A$H67*GH&@6D>D),B9,&7G7'005@2&E60<5
@r1422
CNNGCCAANAGNGCCNGGCACCTNGNANATNGAGCGTGCAGCCACTGAATCCCCGCATTTTA
+
$'"%*#&(!#%!'"%"&((&*"''!*'"('$$)+(#*#($%&+""#!%)&(*"#'')&!")%
@r1423
TGAGCAATGGCCAGCTCTTCGTCANGCATGTTCTGCATGATGAT
+
(7"+H+H/*,#48%/./?)F':3#+AG8+2BH81C<?ED<#6$*
@r1424
ACGTCCGGGTTAACGGCGCAGTTACATGCGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGG
+
%?4,3/B&&7+#AH<3=9%1!5F<!1G&"#:F@$,!!"@0A6->AD9%<C41!(8"DED/A9#1-F(6)(+-;245D&2?3'@3#!."6"45:5"F,0B(2$9D@C>*')A9B
@r1425
AGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGC
+
&<AE#B*//D?'-61!?@0;E"-D$G<2A5891D=*/EC:7->(7?;-A?17F.A)!4CF+"3))*9=,1H<E?&8D+5C,+1*=.F:511!.5&H4##G-1+C?.8G=?;;FE,$7?"F)9-(5C9:(!%3C6.,*91B/#B<8F127D#4C/*98;HF37C+'@&6=''A5&;-"(A575*ED$==);(+6<?3"95.*;68.4A6:6%7-.9,=7*9"*F#@-'AFG,,E<E'.55;/9'%09;&
@r1426
NGGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTG
+
$)/)/!7A9<*<,:6CA:77:!B!ADE%;=>83H</"@31;D"<95C=H'=+;:H@0F<%
@r1427
TGAGTATTACGAAGGTGTTATCTCGGATGGGAGTNAGCGTATTG
+
D&3*;";%,.;"3>HF;F)D'BBBD"'%*28:6&2+;H5,8#4G
@r1428
CCGATTAAAAAATCGGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCA
+
-=?*D6>#)!%90=.>#:C2!);&*-+'=$?!8&GH+1<5'G@7D69"$D;:87H/ABAF<5>:/<
@r1429
ATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCGGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCANCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTNTTTTTCGCATCACTTTC
+
G7>+))=A3>!8*%.!=.$$6C>:H32/"%%F?66:7(,H'8G(,3F-4)2HB%9?=1::1>)3+"EH,707B2==E.=$3=@?@#9;G<$?=)*=.,(3:#1591!)2)%5/A!5$5096F98#=**@8H'8:#B===B,,D@-/2>$;@95ECF?'>5=4F',,'+:/G+3E00.(+G1>5D#1E3-,*1=F,$"#0'6+3:BB0*.D(=7ECF/-GB$<E7
@r1430
NGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGACCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGT
+
&%+$+($%$+('#!+&&$%(%"$'!'!&%+!*&!!*("$!%)$"%)&$&!+!&+()*+"')"&%'*#+'%'&**#&&'%+%!"%*'%&"&!$!*$"+%('*$*!!!$&%*+"!&(!*%%#&+'+*+$!%"&(*)&%&*"")$&&
@r1431
NATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACA
+
'=%E13&/4.2E-#A*;4"92?4:@,#">+71(:((/:?EC5,"#-44@@('3E8C)<B&=/2(6@?+FB%?-@
@r1432
CGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTNGCTGTCAGAG
+
,=7B@G>7?<,#1D5370/'>D.+$H.!9E=$;<@@&>B:/:?+=)@B#A'+"&:.BC,".,-
@r1433
TGGCGGNNGNNAAGCGTCAGGCGGTACAGCNATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTAACGGGAACCGGCGGC
+
$*$((*($%"*!+!*($$%'%$*))+("')"!'++(%("#)'*))*$)&'")#%"'%!"%#'%'+$%"(%#(&(+&++%*!*$(&+%#!)(
@r1434
ATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGC
+
(7E90G-D,G1!1$5,,(D$2(0<@"G-E*4G69=2=%D589<D#5',@5$F*A$(F/A2&/<=7F42=.*)</*,*99"&:A>:@9G
@r1435
NANAGAAAACAGGATGCNGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCTGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGNCGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGNTCGATGCGGCGACCAAATCN
+
&((-&4@B">*,*1D19B),'E;E"8A%$3?975;D$5G;F:A.9$<A;@H(D9:GH&*';G&0&'>12@C9>9586E/9&*01A,D(#53=92@<@&*AH:#@0/%F$BA4G5="4/:E9C+89BD@/:1;0A@=GC6";H5%1#;6&.26&-5F..52C($?@8'>=5405A7:,B*?;7DC8:0<27$%"0=:=6FA)6)FD+DG>''9F*+5&8H1AA$&%!;2:<6-+0+:D+*B.:$C/?)(9.-76@B(!A-@G.2'<(92&"-8G181E-=C45<:BD8.,.,=C.@!!5B4@$6#C1!G*>F$;)9*E>@BHD;#(F6AGG*:9B*H2*D&*:%E4?@+B)9+%+
@r1436
TGCTTTTTTACGAACATTAAGCGACTTACTCGACGCACGCAA
+
7=@H8-9=<.BA7:+.@4,<938F*+C'0<GF8?.,0A#B<6
@r1437
TCGCGGGGGGTTTTCGTTCAGGACTACNACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCNGCCGAGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTNGTTGGGGTA
+
&<>#0D$)5*H$D+@6=HA39=*5$G9$E-/(B:4D*;*(3B*9,%:73-.2B%.).?$:-B;9/?/'B6/AA!6&:/=H9:3<(,./'%0?3G"G!@G584>'@#1H-9)?2'F<"2=EBD!.G73B?-9F23C/)))#56"(."'(5:!40
@r1438
ATTTCCAGATCTGCAGCATCCTGAAGNGGCGCAATATGCTCACTGGCTNCCTGCATCAGGCTTTTTTTTGTTTCTT
+
1.#9..>E-C>(2;-?,:5'?D/:-2,(,$@08D)!0.B><261/E39AE396!E'FA25;6)FE?-@D:%6@84.
@r1439
CCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCNTGATTACGGGCAA
+
="#39=G7<D:1),G9-,<FA-E4=95F$?C@&//HE#$E/"@4;+;@,E68371+A>A=D%F#*CG(#/2/1%@47D65"2)=*%>C7%+58HA0@:43'5E3$%=!-%
@r1440
CGCANTCAAANNNCCCCGCCACCATCCCGCCGGGNGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGG
+
'(*"$)&)$)#'&+(+&&#"+"%()"#%'(%&)'&$+$*($)*("&)+"(+%($)&"!$#'"!$%)%)'&+('"*&*$
@r1441
NACGAAGACGCCTGGNNGTTCAGNGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGA
+
$%+*$&&%&*)*$%"#!&)*!#&&(*$*)#+!&%**$%*$!*$(&&&*#&!+$)&#*!(%*
@r1442
GAATTTNTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATCTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGT
+
*-$;/")F2G2:5FGC0>EA0A,!5)H8!C@%51,?B3B?EF$"2.;+;.$!?>H935;4F1HB-45$E--"@?887A=(=B->C1D/"2>1D?<7=2(>2#34.<BE$.HF:!$-%A;869
@r1443
GGCGATCCGATAGATGAACGAANACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGNGAGGTTCGAAGNGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATAAATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGG
+
8"69H695C$>8D?-(=<<@;"B/1-'&-:56'%:D,'#F;.=;C=5C7<$79*:-A&#BCH(.;F>?%%$9C>.@825)+=(4,2:BE@1$7577C58?,3:09"4>;27$8#&H2F@2HF'??;%',2;;"*7:CE.C.F#'=0,.44!/E9F>15$2.-D2='B<=7A5@A55F62@0#!+>C,,*2(<+0@45?0>E<6<(%680+B6H5:,H%?='4:>)%!5@+D3-++8A-8$H9:(:D:-8<A0<@"(CD3<$G!>/C%29$?$6!1G6>'-@D/E4D=6+/8'C(<&9A#H#%
@r1444
CGTGATTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATCTAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTN
+
G7'H;;94@!B,*65'"%8H$.FD(@477E3D/.<;!A)B:E(44';4('2<.$H=?%:.09<31-)99CB?!1=!?7>-/H051$2:>>#-,8)D2=G3A""AD%"$#ED:,<+)B@#..5*F(,08!<)4-%41DB5=)/:4-(@>+=H>AG9D9%@$9F:H#2G7(7$$A9(A8,@A$HE:9%-</EE
@r1445
NTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAA
+
""+))++$))#%)('#*'*(#%%'%'*)+#!%&+%#*)$&+%%!$!)+#("'%%&#%#'!"&%%#'+'%$$!('!#!&+)#&(!'!*&&&++*'##*'#*&!#+##")(%#'"%$+!"!#(&%)'"+(""&'#&&#)'&$!!%$%$*#$
@r1446
TTTGAGGTGACGGTTAATTNTATGCCCAGCACGAACATTCA
+
?!%<.2#"8@<>%"2FG3B8;-4=$;4+?H0!@H>64'%9=
@r1447
CNGCGTAACTGTTTCCGTTGACGAAGTTCACCGCANCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGG
+
#*"E#<,>E--A(1.7(3H$%$B:+3F*!=")8%1"6"AC97>1<&D*-59,&/3&<.9--1":0/F"+77/GDF.=,/9F)%%'C?821#@*&A(+?%@BF@!H+1GD4"3G5+6G8EGAED@0$4$2+7HG0@H(3?>D@=<61>"@5<<E+C=G%427#+;*)=;@:G&)<BC)-&>02/&,CC!B>3D66@.->?
@r1448
TATCANATGTCATATCCTATANTCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATT
+
))!''"+#)('!*)&%"(!"$'%++('$&#'#!'"!)''+"&(%$#&"""*%)(&(&)&#&'%)(!('!&#%#$%+&($
@r1449
TGTAAAACACATTNGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATA
+
)24A;H7)9);%4E&1DC+':=6B*A'&1@8&4&83-.7??A=7&%5D'0@&(@=!53*,3,'%H)"31.-=<6>E>D288H.$>6C)09<.=FE,4&&2H?*39"6,/,1>"7=>+CD.:4&63$+979A/F5+9%-"F(1AC*='F
@r1450
CNGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTC
+
,@E?+H5!*2-@2CDG()2C$&F&F#B,)5$="H3<6+(B4"07F.G8C-+%
@r1451
TATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGG
+
.EB(G+E&H='9H53@83+91,4A/,#/&9C$E7+G1<%H3../:1A,8B>C,:E64)H*'4CB
@r1452
NGCNGNTCTNAGNCAGCGTGATTTCCACACCCTGTTGCTCCA
+
"'$"(#'"%"'#!''+###')$&*+#!+"$%&"#$&%("*#!
@r1453
GGTTCCCCTNATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTNTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCAN
+
/B4+DC2D3:H'47)%1"+(+4/,2&H/741/<E&8/E&.@"0/EB?.9(.7%";7*A*A:G302.6'3E1=.H'C:)&8G8$-*!4$(1)H0B)4C:F%'F7/=F=/@%=G36%C!$.4/-#36<G.688=3%%&='GF:;)4<!.8:")+!?#29*?B/;6*A-8354",GE-?-03#F=B4B&!*F(:$<5-2+C11(F3(H88-(:G1>(:<B:D,6B0389E(1DH&);+2'//?9;*A8F@6;+!H-1@>
@r1454
GTGAATGGAATGATTGGTGCAATCACCAANCCAGAAAACAATGAATATTTTTTCT
+
!2B;6).C'&C8EFDC04G.'F2-8:0C*@4+D?F>'8./?F=+,(FD'41*-1,
@r1455
CGCTGACAACACGTCCGCCGGCCAGGCTGCATCGTCAGCTCAGGAAG
+
'%'!)'&)&!+%#%$")!$"%+(&"))!)&**#)("%&#*%(#%*$"
@r1456
CCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCNTGTCTGCCCAGGTCTCCAG
+
:>@.>E/0>%2'G5F1D2)4(?D:B1>'##5:,5/+1G;"8)7%3?%49B75@+'4-%%0BF.!"D%C
@r1457
CCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACC
+
/,G(.+&12C8"=C09%BA@.0B$!.8%'17EA'A<1%.50>C53))1E&7;C=:*8?,F',G##4:1-0@A2*3-HGF
@r1458
CACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGG
+
<35)=D9E>=92E?$C%/C-A/;D-<.=3+21.>?(C6*3=AB%=8C*=BH2<'4+F=!E1<(A7&1+2G=+'"B3E-B2F>F@E<*=D:BDG>&DE0*(G"-2
@r1459
TGTAAGGGATGTTTANGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGC
+
E(*?3*5':H/1G5,-#)!@%A.'F$2?9&@%8)<.D!#@C1$5GE&$-7=$33-@>43'4.9&3*5#8H>F)@0H/B6F31?0G
@r1460
CACTNACCGGAATGCCAACAGCGCCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCGG
+
'+(*!*&)"'$#)"(#)%"!')$#)+&#$%'**$#%($*&$&(*#")$#+(!*)!'*$*&#%&%*('+$'%!'&#++%&"'+(#
@r1461
CAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGANAANTTTCATAAATAGCGAAAACCCGCGAGGTC
+
3F"0,544F+5G/GD.+6,3HCC'4:045"#%A1.7;,5F)55H+"4'<.552-9D<A"7=/#=9!AE"/CED<:5:(@..4A)A-<(#?F!#E'5"9
@r1462
CACCGNGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATTACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGNGATGCAATGGATGCAAGCTGCAATCGGAATGCATG
+
D/20-78+,*+B)@,3?<D??7#!8G"/!G!E$F."/'"$;GH$$A/<C,/06%6:!#>>0."/$-7"3!(2G&#6;,(/<9EG;'5BE?*6@.A6#??=9323!H-3:#F$#1F8!*'(5:!,3?!5/B3C5A?;=B4:/;F)9/?<"?'8FA0*B5.7?G.AD-):3/H6<,+F7++#05%,>,&@)E3FC@CH<'7197.-:;?>.+=&*!#182,H
@r1463
TTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCA
+
B@7?.#!1&'0EEA<3.+9..30*22G6;;)@)A8A#-8C.:A&=04=.$1,#*!<?>><<GGF<HB-:D6#>G5C-B>965=;4)-5DC0'2+D%)')BAHGC--@C+3<.B4EC,3#6F!"'101502C,+-6&+B
@r1464
CTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGNCAAACCAAGACAGCTAAAGATCTCGGCGTANATCAAA
+
;ACHBA(&=D:**&$%E"3DC?FH&=@200.G-+@&(%%B:EG+"<#33!>4/52=7H0)F>,1-0)D;2A91#&=*4HEH7*B2E:01*BFB'H;0<!8C04!4"02%=C;2G6B4364!%)2H<-!0---'
@r1465
TGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGTAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGC
+
9="'+,((?B#428#;"DA34*>'BC35;80B.G08=9:3+B$9*0=:8"?G<C<"D13'%0>41CG'7.%HG#CCH;D/B95$?1$<;F1-@&,*B$)D%C:7$-:-GDG=6,/E+54A9B+7-7))C=876D?(0+)%'37+=5:4$!4FB:(:##E?D*"*,8B:>D1
@r1466
TNGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATG
+
431603#G#@-D):59@'$,*3A&#%(2"091,$/&5@F@C(B5%$12=/D.D"0%EBBA*="#?=)?;5*:@DFD.=*?!F;6#6"7G?1+
@r1467
TCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGT
+
>,#,>+#+#8/4<+#'3*'""H<6A;%;+:#H&'>9:287D,4FDB'"(F'+15F8".G.3=H@&D<%D+!.CD:%'8:#%*G-3,>(G'+(B:',<&%+$F,D2)(9B,,4B%)@6#
@r1468
NNNAGAGACACNNTNNGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTAATA
+
"!)*)%%(*'#!&(&"+"')'+*#"**%'"''!'!*#)&&!'")(&")!$*$(!+#+!+"!#(*&!!++
@r1469
TGCAAAAAATANGTAAAATCGGTAGCAACTGGAAATCATTCAACACC
+
9'%%8)032,-&.H#FC)C11"BA6=54D>?6HA*=@#,G0/5E5!D
@r1470
TCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGANAAACCNTAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACANTATCAAGGTATTTGATGCGC
+
%0A==6"GCG:0G9='C3>-B%F7<1H=!9/")0F,%E8D"C:59,91;);.$9>?+*+6##(B2':G(+'9//9??A4-<%$'$&".6/'7**05BG4(=#)9$"&%"9A2E2%A0E2DE@D$
@r1471
AGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTNCTGCAAAAAAGTGGGGAAGTG
+
<?*HC!D'%(18&>%6BB5!<!?(A2?*?'9>C<:BD57889/CF&HG8'7">-D/";B,#!D/07!!"E'>'=92-?:6%E+F-9E
@r1472
GACAAGATGGGGATGNGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATA
+
7*F8*8*E!1='674:-"0;'@AH:#G=3+%D8$(:-&*7"(H()A+.EH9G=5H/<5))1!2G2$H@C/
@r1473
GGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGG
+
C1*G?F:2092,&-''4F0;;-'#"310%2&!%1B-'C!D8(;3C
@r1474
CTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTNTTTAAAATACCCTCTGAAAAGAAA
+
"89?<%$(1)GG0;C@.-/766<&F9,.G/C7$5/'>;D74%"(>"?0,#)6!?G8:0@8.DF,6'@EH-38G*D8!H!/%"B*,6:)-
@r1475
NTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCG
+
!(3"9%!(6"3B";A/41+610B7-G&)#+234B;<$G0+7B3#67H-&?9
@r1476
GGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGTANAAATCCGGGACTCCATCCACGCATCCAGCNCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCNANGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGACAACTGCCGGAAAANCNGCCTCATNAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTNATTACCATCNTCAGTTGATGCTNCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCT
+
0H&;HA58C.FC64-B>9*%6F5921,EG41;(CH(D+&"E>+<3@E8B9(5@4G+7$!AH+<>71B)5H:5>.$6@8+B=H@4E'D8A>4*,HE/A9DDE"?A(>#>!:326GF<C<20+8;"-9"D<0D<5>$#@#/:>60!C3@<F#.04F"0133/?"0C-732-))/0>>5<176+4)9D%C3*9C4?5G1:>&<$.1=*!!.)<2F9&==<+3.<B),7"(.1?*H@:C!42?*2!:!..(*H7<(!20-8?:6>C9#B0&$:B/+(A3!C<'F+EBC:G95844:+7"50$?$9#8.":9&E=+B+"93F5<3F1'CC@!%>#B5630ADE/9<+#6G(-5A#"800=8C1B@6!+$(*1?&#%A74)''*-$*6/3$>*F@'$*0&-A@""$=CB9<:A:$3?5:64%/;>,:G4+#'>DE0C;92:A,/?
@r1477
NNGCCGNGAANANGNTNNTNNNNAATNNAACAGAGACANNAGTNNCGNAGGGNCNGCNNNACCNCAAGNNTTTNTNTGGCAC
+
"!!#""###$#!#"!#"##$$"""#$$!#$"$$$!""$!$"$$"!!"""$!"!$!!#""#$$$"""$"#"$!"!#"$$####
@r1478
ATCATCAAAAGCAGCAAGTTCATCATNACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGNATAGTCGGCTCAACGTGGGTTTTNATAAAGTTCTCGGCAT
+
;A+!&4?=.2H&('42H"&1&B@-'3?!"#"C3%"3?(F'A088%>C4,)&(F101G%H@B&&:C2:@B%?815,/GFE0BF+8?1C%..*.1*$8F1:4%$:41<H93/.H=;B=""5%#DB)H9+.<0%.&>3''DG9<3*,6$73$A'E57H4@:>B!A2E5.3)(2H@C3H$F-$$+@#D#=1B)'+"3BC+1C9%#<*<24,07'99F*'@8"B<CH/8H/,
@r1479
GGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGC
+
''++)+'"**#%#&&'#'!+$%%!$(!!"*+$'!*)*++&'($&(!"+!(*(#"&"#+"'
@r1480
AATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCC
+
-'E7B531:D<$-4H1$<E>.32BF*-E<H6?'*F%$'B/;F-'99AC/7#$AG$+FC>*H36%#&40-;0<*-@2*1=9CH=;!;611@E@:4>DE0%*-4251.41>1?.!$
@r1481
TTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCC
+
-$+814"DD$1ADD>97>9,,9%B!?&9F4#83F0'9'A2=&1E@#7*3&#6&;G6F8G.6@C#$+=&01A2?;"'/E)'1;7
@r1482
CGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCT
+
,H&&:@"&"9H7C)')E@-"C+816H*CB$?%;&8&=@E/>6*14%/?."
@r1483
NANCAGCACCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTAAATGCCCGCGCAGTCCTGNCTGCCCAGGCCTCCATCGTGCCCATGT
+
!++'&$%$&)#%!!"**)#*&(!+#%)$'(+$%*$&"+"!#'()*+#"#!%&)$"&'#!+%%")($!!*#**)#$(&!+&&*('!+!(*'&*(%!!+$&"*(!$&'##((
@r1484
TTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAAT
+
)G1&0.!'>:!*=1D(97%.,<8(&(><</':F5A=@)!)933:'(G&(D8<C!@C)?4"-H+;3"7+?*..:A25D2<(H!2C
@r1485
AAGAAACAAAAAAAAGCCTGATGCAGNTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCA
+
<'.&.860;@C-/F7,8.$@;$2B"F2$/E>/15@4!%.:3$@5B)4B'BH"0>,A/+("?2G%DA1>=/3-;E$5%;G>*;12..!A=G/73!*2&/%>DD#"=;('*(<6&+C#$3E9('?*D?,B,0"2DH4(')6'EF,?D)0H1':"
@r1486
AATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATTCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAG
+
+:;C+.,>9*?2&@&227%::33E;&'*062G;.5(66+*,@"128,/6:,()0BG;4C-C<&C2,7H7>/*:A2CC21&"@;$"C@/+15&1C"6E+*@7-;;@@45@3
@r1487
CGAATTTGCGGAGCTATTAGAACTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGAC
+
?"(F0G@-?4?'DD2%E92A42H=?%D.9;'D&"5:&"DAH+><33B5/:7G.;0H3/A1"!1%=G0
@r1488
ATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATG
+
,-D!*>3-&D3)1D.'&D+#'B+FG@'+8,&B/=1/,,47?#/%-""B0@$!%@B"'!&78D"!=:1,+75-*"2,.")EA70:;@$@H.EB:G
@r1489
GGTAATGCGCGGGTGGTCCTTTCGCGCCGCAGGCNTCGTANAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGT
+
*?,+D(23(&)H10!B1C&+:F'F<17BA(>+*>,38>)*E83D35?"9,;FH21&)@-319'1&>+A!7$B73-<C&3G-6=E.6A)H=,316#44?=EG@<B;7F%?,57?F3@
@r1490
ATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAAT
+
9)$'=0":$&0/*1>$#'*1-BD3EA"D103)->".0D"<70D#+)/,-D&;G!1'&4G;:<
@r1491
AGATGATTAAACCCAATATTACATAACAATCCTCGCNCTCGCGGGGATTTATTTTATCTGAACTCGGTNCGGCGGGTTTTGTTTTA
+
0'>$10&36;'(=8)D&/#8+FC#.)5!10'=D!9>.0(1F/$C(?C'/!)F@/;$/:*5?/:$%G4-5>B:>">*'$6;-4<F-$
@r1492
GTTAAACAGATTGAACAGGANGTNCTTACCACCTGGCCCACGNAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGT
+
D4%6$<;D@2D:&8-5'2=<&GD+EC:,2*)5,01H=+#'$?-#F;3??@&'91A5B6H.#8A*;($(?B9DH'<(&)$9#E;(8)-2&F!D2*%%)7@?;F0)",D26H7)H>@/-$7#,F9A1.=2;@"7G)/;=.."2$!,G.$D@E33183:B18<$'9?;F@?4B22DH>7%1*FA0.B5'(D%:"D;*!!,--+34("">?@5?-,/7=0"==(0==37+F#6A0$H.C3"%8;&4,=64<"'',$3<32!4=<?%@@8#"-&>'2F#GC?&*#-:<9D)0,5EG#!%"<..7-!&(/3$H??.2@5/G/GH;3#4%&F?*?+6AH7F4C>!0
@r1493
TATGTCANGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGG
+
)!8E/0%;7+F>EE782/4#9:.(+H+<F?**(&#C).<(92D&)>@:@8;(*%&+*9!@$0(+0G%&B))8/0E!)'?.%1C"7BC">+6H?.@2=;7
@r1494
GAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATC
+
#'1>!(<1'H=!?C%%)H<DEA.?+&?;;-*B")-5G';F!9=G/:FDD!&A/'856!',16C1>9@+"8A5
@r1495
ATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCANCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCT
+
&3<-15*:GG0'=D@>.=4-/?8H%9.'HE8#2H+1?B*!2:5=/&ED-)H3@3G>/>2G'HCE90E%85F6!BBH;=G(:C%?D4.=ED='&3#></#G>--;<$8;2@;1)771*1''G<HD!F@0+)5H)'/8F9H!=H"-0/F(F7:->77842">H3@G5*E6>!?680:F;@"CB21.??%=8!:!+"%E7<>83;D53!;*,C!A!FE&,5D?&3@%*2-!$9<41:!:)B:.G=D.@G<6;4D#.935!=
@r1496
TTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGNTGGAAGAGGTGGCGCGTA
+
'@:+H5171)?<77>/<,#,5:;4E7.G?/9;6A6A'0<!32,"5/>4>&#FFH#*,EADH<@%"<:&C:D:),38C
@r1497
TNCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCGTNTGCATGTCAGTAATTGCCGNGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCG
+
&#7@1.-9H,B)C4B(6$?B@03,E-:B.%)1-=+1&4@A1;</,C65F1$8+(6"=FBGGHF1=*$+292F*;A/F,A9>D:"4!++)7&&>HE6+$H*,,'$(DG+8%+4B:(F?80.>A35:B
@r1498
TNATCTGTACGGTATGGTGACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGT
+
("$!)+#+&)!(%+&*&"**#%&("+*&!!%%$"((#"*%"%%%)*$#!!&"'$#"%!!$&!%"$+*"'%*""'$&+*
@r1499
ANNTCGNATTNNTCTNCNNAAANNAGNGNNCCAGGGTNNCCCTNNANNGAANNNANTNNNNGNTNTNNAATCCTTANNNCGANNCNGATANGNNNANNNNGCNGANNNCNAAANTATTNNCNNTTNCNGCNCNACNAGANNGACNGNNCNANAGGCTCGNTCNNGGCTNGGNNNGNCGGNNTATANNAGNCNNNACACAAGACNATNAGCNCNAACNCTANGNNNNNGTNNNGACG
+
$####$!##!$!#""###!!$$#"$#"!$"$$$$!#"!!""#$!!"#"$$!!$!#""!$!"#"!!"!$"$$#$##$!$"$""#!$$#####"!$!$""#!$$!#"""!!#"$"##"#!!!$!"$""#$!$####""#$"#"#$$!$##!!!##$$"!$$"#!!!!""#!#!"##"!"!#$#"!$"!!$!!!!"""#!$$$#$#!#!"$$$#$!####!##"$!!!#"$$!#$!#!"
@r1500
NNCTCNTANGGNCNNNGNNNNANGNTNANGAATANAANNTAGCGTTNANATACGNTGGGTGGANTAT
+
"!$$!"#"#$"!!"!!$#$#$"!$#"$!!""!"$!$$""$"#!#$!!"!"###$"$##""!"#"#!"
@r1501
CATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGC
+
(*=98D3?@=<7*A3C0,BC4)/9%:*F08"BA"*"&3=*A5E$F0&A9>9CHBC/#?"%G#B'8.A79!6"8/';93/3H-4*4:;AFDD/9;3!056<&.779)"(3#0H74"+1@+H,24"
@r1502
CCATCCGCGTTACNGCATGGGGAAACGTCTTGGTGCGGCGG
+
?%&-)!$@!<""E:<A.4G>'B"76%CE<=BC3-1''+C71
@r1503
NTGTGTGGCCAGTGTCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCNTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAA
+
!+#&$!#"&""+(&%"!(%*(&!&*)#**")%$+'%"+(%"%($&(*)#%%$&)#()*$#''(*+&!($*(#')!!&"(*$+"+*!&)+'!%!"+$+!$&!)((%(!$!+)"%$"*)$*#$)"#)(+#'#(&*#&&!)(%)%(%!+#$('(*#!*#"%)!)"&")!+$#'$**#%!%%$*%
@r1504
GTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGA
+
F*2@A*.:A6:94??E)!4/+=%6H33<DG/C!1::066AC/>,6B-.<-9./"A@'&8.
@r1505
NGNNGNNGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGGATGCCATGTGGGCTGTCAAAATTGAGCNGACCAAAGACGGCAAACATTATGTCGCNGGTATTGGCCTCNGCA
+
!(#%#)%**)%+##$*#&*!&&$!(("(!#+!*)(%!&$)%!*%"+%&*$(!$&$&&)!$!))!+%$(!#++%*$(+()''!*#%")'(+$+#*"(&&*'(!*&")##$)*''$*!%$+)$(*#'#!"')##*!%'*"&'"
@r1506
CCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATNTCCCCGATACCTTGTGTGCAAA
+
+!GB373)EE&;)?H$69CHFF;<6=2E,%@'5)<;=)5C@;D,8*3!0+=G(H,!8*:6"C@D%>%C:92BA,*9/;GB)79"#!:0@',B<?9?67&#:C:142>+6+0)%41:&G3AH12;%-5
@r1507
GCTNGGCTTGGAGCCTGTTGGTGGGTCATGGGATTACCTTCTACCTCAAGCCAGAATNCAGAATCACTGGCTTNTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTNCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATNTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATG
+
,=%F&?;:6923+@2H/#*??/)3<($7?*G,!E60E>.5)>>C?'9C<38$B672>13/2%;<5DCC=57H$369=E=B>C-?C<71@@HG76C.BE$GG-F34C;,E(>-1D+;G42/G*G&:0&'(B%2<7C!&HH&:5*,$B'D)=6#<E(@D?/B</'D3)7C8*B!8".=>?=(H(B,2&6DC'1'C0H?.3*G24CD";5(EA!D@!6/60D1.*+#-!/C57%E@8A=<=F&!4+AE/#%/A.C/+9*B=/&,H<F/6=*D@<+4-<49A.28@=??BD.9%?&48",D!=C=(2-,3<3%F4-@HA=A:
@r1508
ATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTT
+
/89<6<(*D756E<AE"ADDADF$9"1.*%4444?)$>ED4+'F+E?8.+7+4(A+.A(H3@)34D<%:54&2+1+,=A?<E,C21<=+*E(&:8A><3-0$/=1?D+#0H:F?D8(/+'B@%//C,B3;.9-.
@r1509
CACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCNCGGAGGGATCATCAGCAGATTGTTCTTTATTCANTTT
+
FC-*,5F!A2>:BH?)5#9D.8?GC0,!)?#=?F#G7/CE';@E%B14H(%#($.".%$C2H!7@#G"8ECD/AC3@83=2>F,205)H37/,$C$+;H<221#,F7A0$:!$41A2,2$D)0+5.
@r1510
ATNNCACAANCCTCAAATTGGGGGAATGCTATCCCTCAAAACAGGGGGACANAAAAGACACTATTACAAAAGAAAAAAGAAGAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTG
+
%(!##')%$'+*")#%&!&"#"%'%*+"'$"!*#'##(%&%*""(')&(*$*+%#*"&$%#%'%$%$#$((+'')')"!#!"(*$%$""('())&#(%'%##'$)!+&++#!%$#"#$'""&$##$+#!*#&!#(#&)'$'&!'
@r1511
CCCGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGAT
+
(((*%+")&"#'""*$%&!"+&"#'()$&&&!)((((&%)'+#$"()!$*&'((#(!&$+++%'
@r1512
ATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATG
+
C7B>26;&F>4,7'@-+,5<+(G2H81A(()5:#'?,>%&
@r1513
CNGGANGGAAGNTGTAGGATGCGATGTTATCTATCGGTGCGGTGNATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGT
+
(!*()''$#!#"*'$'%+##*$)()###*)"*')&(*'*($!$&!'""+'!#)'*%$%)!++!**"'#*++"+")'))+""'+&#$$'&%!*$)+((*)&'$%($!)$!)""'%&(%('#(&"%+#!(*
@r1514
ATGACGGTNATCGCATCGGTGCTGTTAACAAGTTCATCAGC
+
D;H/(C="59)?*-A+>3CG1-F>E"$256(@!D-8F)A&D
@r1515
GCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACAGCAGCANGACGCACT
+
<H5$'E8<#F-4*1'@C5>;8/4>==++C'5?0B@,G$&08(1A<'%==.3#?9AD7
@r1516
TACTCCTCCTAAAGAACAACCTGACCCAGCAGAAGGTACACAATACTNTTATA
+
"E.DE7$,9G9"#C4+<78=8?",?38D,1:$B(*;D*%3-$.%&:.+7-050
@r1517
ATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCC
+
=GCCE6@08%"/*H;E<4,G!A94'27)!;A"";)@:3+<F/391H;!!'-??FC+!',.4D(/
@r1518
GATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCATCGAGGATTGAGCTGACNCCGGGCT
+
64'+<H&?04!)%:,E?%H6AE,G<>042>5E-8EC(1G"41(:C#4.061H.F8@<<+B6!)8%79/?%
@r1519
GACTTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCNAT
+
,+B>/@74#%7@*0&,79+FE9=)88!%#0GE'=G6>8,'&9
@r1520
GGCTGAAACAGTTGTTGATTGAGNCTCTTTGGTCATTCGCCCTCCTGAGAGACG
+
=%+&%477/!%448873A"77'/+-!#3<9F:G%17GG>?A?4/,!('3A$<.<
@r1521
AAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGNATAGTGCAGCTCAGCAGTGCAACNAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAAT
+
B:*G?7GG,%/H:**-($DE%7*8E!C-#8?(;3'BACC1=?F=!@A++;G!)55:<&%<>;E521,..";&+F>,,7!;1<8.=G1*D#(#"D*?&5G&D20:*#"'G-H=+;!57CB2"A3DB5#!>F&:,7/G5H;/1A+#@'<%67%$"D?'7=7#0B26&5B,;3F).6DC8/@==H%F-6+!B<E
@r1522
NGTTCATCNNTNATNNTCNTTNNNACTNATNNNNNNNNCCCNNNGNNANNGNCCCGNNTCNCNNTC
+
$$!""#""!#!""#"!!"$$#$$#"#$"!!#!#!!#$$"#!#"""$!"#"""$$#"$##$""$#!"
@r1523
TNNCTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCNGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGANGTGGGAATATCCTGCATTCCCGNACCCATCGACGAACTGTTTC
+
(##+!*'%#(&"#*%")+*+!%%%$!#!(%&*'#'$!)'*!("((!&()(+))**)&&)#!)$++$$*)%#!++*+&"*#$%**+")$&"'%%$$#)(&**")'+)+)#*&+&%%&(''!)%%#"!#)%*(&"++")*""$()'#($$(#"%$&(+((&+((
@r1524
GCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATC
+
2%&/05=*-B+,%#?$'@!%")-&C46?4=#)3/(92>:$#9>:@)"F86+>C4)88"+!<6(3<BC*3*0)7G0E0G1F&CA3DH0@<$)#B0E;)A+
@r1525
CGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTNAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTA
+
&*&)(&+"#+!++'$)"#)'+%")&+(%()"(&#%"'"!#!(*'$'&'#)$$'++&#$$&"&(!%+))*'&"()+)!(#+%*)#$!&!('%(&)#*'%&$#)*!%$%(*!%%&$(&$'%"""'""!($+%%&+++!("#)*"'))%*!"*"'$')!"'$!%&(&&*%(')*'!&(!$%!%((#++'()""(+')'&%+*++*'&"+''!)"$!"#!(
@r1526
CNNGTANCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGNTGGTAGAAATCAA
+
'"!++()"$%*#)!))'+#%%&*'#*#)$&)'%'"!''*#&&&&+!!%'#)''#*"
@r1527
CGAAANCATGCCACACATGAGGAATACCGATTCTCTNATTAACATATTCAGGCCAGTTATCTGGGCNTAAAAGC
+
#B(,-CG3#3'+89D33&G,9E$&4093*@<.B9/0F(5($)B!%8,4>C5E%=1<(B3A8!:BBE7H.>2!?9
@r1528
TGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACT
+
C?;>CA-)BDE+F4.(03<@7?)C(D:%D!.!>5=$"">*'A>$,7.DE(;1#<"$B
@r1529
CATTCATGATGGCCCCCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATATAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCC
+
A8*@64)048-G+:3=05B68+'=H9+FECH5H<@/A8D+<#@";(A9A!H,-/+,!',$:%E71%H!B?2"G;;18D741F@*+BE09)#*4;B936<,">G$((+8<;'@E1.F#0'G3D?)6888=?G-B%B+-
@r1530
NNGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGNAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCNTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGANAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAA
+
!";?&G:$B!#@/@C8/2:E)A/'(E0265!6B&/0AB.H.?5?5=D;?*C#HHC/?5+6+CH83,19:C"@(6*#5/@/(!3G9+/@#;4'&%G(11249>F(<DE27.@*-/,.6?@"&D)%-&,#'2G4*B:@A-!()0+2HD.('0E/!$3B7;C/B9&*:"*9F+0038$B,3$CG,,,./G!(:0@*F.+&DB$)B!'#(":!,20-!;!57&208(D3<"G!B-?>,?+31$C+B>,?D"?%&>74&#HH(<+@A23))46%EC54;+.FE/=;5:"A/13363>;@6-)9/G0+D59"HG$#>)!#1',;<=
@r1531
ATACTGAAAGAATGGGCATGAGNACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTNTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAG
+
@<H!':%<)9-348<G7@=+./C1?%7(*;30E75?(,6(-AFH><%%9<H8'.@=/0)3".39-5&/(E*,$1;8#4H&<$;GFBC90"8>6A,<B2A(;!=5)>&)E!->5+/$AB"132(BCC0?(@%G:B+&#.2*F2+'*&"8
@r1532
ATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGA
+
D7<2F('=%1+@4;!>-#.0$,*BH,3,%*#6=?%(1#,;;=,-?)1/.8D
@r1533
ATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCA
+
'AF1&.'(6&&HE!#F.2&/$<5(+3D!#"03%A4803E*,7
@r1534
ACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGAAAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTNTTCCAGGC
+
)2,=158>B!'F?E@*7->!B6H$4&6!><C+B3/-39>B9F#>7GD(+2@9+:&=3>>5&+2%/<.+1<+D48+>G6%'+.*'.7/CE#5D:;@31@6-F1+H5)A$)C$8H9,2#2F3,GE3D/D#G&!(A+80E$-"+@(&
@r1535
CGTCAGCCTCGCGCCGNTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATNGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTCCATATCCAG
+
2FADF&H0:!2:;9+3B?@'.G9"6?B4B=@11))4;>D)-!"A&5C$300F/?'A)#8F#G1?=.:,='G<G#(1GAAD3"*7*:$EB,/,,&9=;@$%/"BD;8!&&
@r1536
ANGAATATCTGGTTGCCCTNCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGNTCAGTTTGCCTTCCTCCGTGTCCTCNATGCTGAGGCCAATACCCGCGACATAATGTTTG
+
:@>E)<@=0>4*"B:1-?/G!@<+2'B>8<H"9%E($G!(!7'H):1809+>;0-33F12>0B@7'E:%"50!1<6089<*8/@B0?."7'GEED<<'9@C.,DGA-3C@FED@.2'&(@@5?B9EC5!%B6,/-!+E%25*5>@%8BF2C'4?:-
@r1537
CANTNNNAAANATGAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTNATTNTCTACACATACGNTTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCNACTGCGCTGGCCCTGCTTATT
+
#&)&')&$)'$$'''+'%"'%*(#+!"#%)"&%"!&(%+&$")#(+'%+##$&(%)**'#"$*)(&##&!*"%!!+(*#%'&#'()#+)&*'&"*#(()(+*!#!&"!!&%*%#!!)&$%$+#!)&!(#+&!"('*)'))!)*)$%$!
@r1538
AAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAA
+
+*+%(*'!$*)$!&+&!!++)'$"#$)%($%*("+$+*#!)#%*
@r1539
GTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCG
+
>8?*(4=#H6597$1>6%/(2H!76?"-<E+2%)&8&48"97'*22%$07A/G;"=7)
@r1540
TTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTG
+
3!<'"B2@#E8.<F'.2;/H<6DG*89#'$.2:=7B*!<"B"03@%-">:#/.6A?"&!4??.614?E;6:DF@'3
@r1541
AGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCG
+
#9?88'##/C9!%?-;G</4-A1.$(4#;C'FA2AC<9=&*58/FD'%H#4&%!@%13G%&+00H;2;*!/&)ACC=C>*@H!@8(!@=&6A1<'6CHDA,9<DGB6BA2.+>9/1C4HC@-FA)-
@r1542
ATGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTA
+
)E$??B5D11$G9&A88."3/3!;HE:0?7F#79E"-H;24,C>>7.G4
@r1543
TGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCA
+
9D8%5>/CA+?B3E,'((2,F='E3H1=,>,DF%D2(-(%?3G(;A"%>;056<!389F6.))';6E9D18?")E+<D@7<5;@0!/>,+C*C!7+#B!E6=/&57@DE,
@r1544
TATGCAATGCTGTCGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTT
+
6B+H)&F55'-1:C@**AB+<8>/FE'4/;&6A08>2?*30!6$A2$C/!5!3G5./C2477!@/H=,>:8&4"'@C2!C4CB)#'%0H7'9+2!B8-!B-8)70@5@D2/
@r1545
GTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGACGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTC
+
7:4""7#1"HG4G:)<$7,<*E9%!-;//EBH6828,126?.3?)?2;;">)=&70&0"'4';E;0=&(<'@#3)C+G?#B7!,C8'9<$6EB/7>%9@9H=:D,GG<%CB/53/-6<>C/D755(/BD?/98'#,,&#A**1#?9=7<?!".-$>#D>3<"<":):.G=,%5)FF?3$/0@8E7+6&F6&A&.*+?G7
@r1546
CTATTACGAAAAAATTGATGGCAGCAAATACCGANATATTTGGGTAGTTGGCGCTCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTT
+
:.@:8.<+H6G>/2?)E;D30#=.7($GF*5.5B5%@3(4B:9'2$6.57**7"/+*8C3$?DE/B?5;?65*:$H3=/83&#34-.&#AF?<*:F1D1)%#*>=4H*>C$2G5AHBF0AD<.9#:G?4DC(F;7:(8)$50+"974!)C#07'$)8!B!5'G"HA5CA
@r1547
CTATCCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTNCTGGTGCCTNGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGA
+
3F?.3D80/-0H!6,$F41(0(32=)'*40!#9;.88G"=?/"9%B1-?8/=2EG=(?DB2(5=&B'2';4C5>6:!<+ACH!=%B921<:>E'-.$;,C>4*--F*(4BD;=)18*"9)3*:GG$EBA8$'D6F!#G0<13C4A4?1<%1<!<
@r1548
TTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACC
+
7>@2#D#$?,)?>D$)3"#3##?D)#1A,+-:C&!26'A?>=14E*?2++>&5.2!%
@r1549
GATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGATCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCNGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCAT
+
<8FH-FE)6"<'D2,,,&@2:%2+B:?*6>3*BGF%/7*0C>A(;9(%3!<--83F'9B3221;@D"B@C/$*+$.EA48!!>@3@G54/"+>E3*9-7"%/#BG9">FA1=%1:5AG#9B+0C@B.H?$&&A--)%)>E60@95=D=:!G-,;G=-HD'!4,4,:E-=,:8@-B6C?H:@&GF*3GE)7C-)+
@r1550
GCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTNCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACGCGCTGCAATCCCTCCTCATCTTTGCAGGCGAGTCCGATTTTTTGCGTTGATTTTTTAATGCAG
+
&+=&FB7H5$10A%@5DH2!,DD(?EBC=A>$-'6:6"5H9&8,A)"=(/'F$1':77/!E=/030'E!;)8!A"/%</H637&9CC;%(83F.-);05>G>@AE>F2*"!E$>C;C-949B$,B"C41(13$>*2,'?9*=C6*'?%*<=27&'6=3>&<>B2)29&<GC'B!=*H4H#@G:G2A<B/!;*;:C'@'(D<'22A@1?&69.'-#8)A4.$@6?-5/.6/0*;/:7'("+9A28'4:8,3)<B558
@r1551
CCCAGGTGCAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATNACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGAGGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTANAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAG
+
;*.@->!"D<624;>C378!>G9.+"+-G"&4;86E'.88740G'.HB$-$;H/"05E?'D<*<(&66@D9;=<E>G);2&(0G9!!;79$/B#'=4-3EE7-1:0?/G/'FF;+!5#-%!2AFE4#-8>'.(?:12'2E?,&>26.EH?,=H6(3%=#,A@3,+(A;DGC=4H&=1B$A$'5.EF!4=9@*)*!-7('*:73@;:HE773/%7(D2"$3G@:C&D#6=7+'5'1*;A'/8-GDD9G<+;.)2?99!6=#;?7%)-6,,0(A??/5H$5G@=;(@1$7G%,<+AG-"F++BDD?D&:*A50?!*%C+>FAG:$;C-)%%G-($<6829@GA*CG&")#3H>+3@)C,(#G2?
@r1552
AAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTAT
+
$-%;&;B($AA7G$1.@86DG=1$7+"AGD.H16./0)-?,"4B$;;*#=HE8':01'#F*B*-3
@r1553
GCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTC
+
2B7>><64A(7'E53/;F3G207?F1(@=,+>+685H'/G+#F5A2H):5E:D:E<&2.#+4H&"E7,%.,:.#>3D,<(=)<E;)H<0(&'22G#@84:>D<>8.%-*"8A8*+&<69+17:E94;#!EF?ED#<5)8+.?&?7>/B(%E9)"!<7HHC+B!!,?C*:.0D:41;G)-'68*"<F;-&<
@r1554
CCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCC
+
B<(.,1FG226"?29$2*3)!60DDF./0(H47#*0=1CE/,@9514$H(B"/D')#@(54*!D$,37"+-"*=C3
@r1555
TACGGGATTTTTTTATGTNGATGTACACAACCGCCCAACTGCTGGCGG
+
:?@,*<%:?C.BE7:!E;*-.7"E=5D+>G&$1"",7!FEA!4+)@FA
@r1556
TTGGCTGATTTCGATAACCTGTTCGAAGCTGCCATTGCCCGCGCCGATNAAACGATACGC
+
$++#$%%#$&$)(%&")!")$%&$%')*)+&&*((##'&("+(&#'$"&"#$$$+"*!&!
@r1557
TCAGAGNCNTNNGTTTGTGTCCTGAAAATAACTCAATGTTGGCNTGTATNGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTG
+
#(*)%"%%%)""+!%!&&(''"!"***&!#*('"$$&+*$'%'*(+)!!(!"'$"$$$*!#$&!*+&#)('*"##'*%%(!#*"+*!""!'(%!'"&%'&(&'!**!$
@r1558
TTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATA
+
1E+9&H349510D/H6"DG"3$*-*+CA?3,@+=6.B?@B,#??3D8>,)-:'!C>:<=>3@(
@r1559
ATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTNCATGTTATGCCGCNTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAAGACGTTGAAGGTTGCTTTCA
+
;&?<5&'-F*5BH?D+2E;7/$2()<88:065:68(H"F*<*6"6&6?#.#;!='C'::=7+D,*0'"%6';#>94*3*(B1/1(/-;31!&6C2HA>83"+4,F&?*H838CB9(1C$@#?E@0?E)'6$:"
@r1560
ATNTNNTCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAACAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGTTACATATTTTGACCC
+
)(%"!"&(*+((("(#($"'$&!+%*&%#%$&+#'!$$)**&(('+&*)))"!''("$!'#%((#!"!(#&")#+#(((+'!'$!*'+(##%$"$"#$')+(#!'))%$(!!"'""""!!#+*!''&$$#!%)##%&'&$#
@r1561
GCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCT
+
320'HA=+265;,*0H!AGA%4A/<@%'/E7$78C&"$(G/F
@r1562
NCACGGAATGCATTTTTCTGGCNGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGNTCAATGTCACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCATAGCGT
+
"&E$=:6H-2F14F+(=H>D3'E'?4"B><9!G%+;D"G#E6$<FAH$1?!F09/B#+0$"8$.)8BD4;CG242$25)(1C16?6&5.EG*64-#-2A$@A-.>6;&:8.><-<-$45@6B1=:$H#27:(/B,$B);6974/+!A6BD?;$&!)<46D<.G*2@,*</6-69!+'>1$E80&G)40
@r1563
TGCGGCACCTCAACTCCGATTTAATGAACGCAATATNCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGNTCCGTATCGCGTCGAACTGATTAGNCGCATCGGGCAGGAAGCAGTAGACGAAA
+
6/>$<>78'#*7@G?F!?6E-D?HAF.E*7G;F!+H+=F2'**!@+#+4;E%*//AE/,*00*'8$?#E&,46?%GE(28B-%3(.31<--6G9D0:93/7,;+*A4.HC-H:AE?1(+"GG3)+<B8#H7$0"4-H
@r1564
ACGATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTA
+
G8.=6,&B-/(<2:3CCGEEB48G%0&@E)>D)4F=H.-?8DG!
@r1565
TTTTGGTCAATCACCTTGTTNTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTA
+
4;B>CG1;)!D/2D2;)H?H8-,%DA88(G)90.&=-".<<:9(4$5=30::*6+9<=1-:D:,2#+)#1-".HG8$%'*&$B6)5HB1%5,$;G<"4.*=,@<0*A$?7(CD?-B!/2-$<"E@3>)?#@A9#%EH>)?!*@-4(9F.-20;>DG1B05/7$8*74=E60&5%;A#,15$+"?$C"1G2.05#+?:!>($G?.E51+7:.%@FH34G2)63;CC?##"0=A98;4;"5>=)4$)?)G)#=&1F8D((##>(DB@4&2/%6C"B)E@148E*%F=96H5.+6H<-
@r1566
GCGAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGNATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTNCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGCTAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGG
+
E/=+D>'='4C:D%9>&4*A/'F<@A5EA)6.?"*-@,0?)<'H*&3"#4'D(G#A*/?6B#(30CE<&/+G3%'<?(6@28>"%G<@7#%8:+4'97?,1CF/76DE78A<-?05=$%"FH/*<AC0'?0AG!/59?#*B"F+)H:D*3-8*C*.&GB;;H(@@*.@26)9G=09H.=8,982<1;0/'C5)40F',D.#<.0=3"9<?.B8.F>'&0&@*AF?B<3F.:,@*4EC;EE)6EG>A36(F-@@.H9'/1A;><9)."#-D-,#)%$&)<6)4!6@+:F@=-*,/&+F/8,24$?E)C)39?'</G?.3"H"CF@F5,E+"8=G@1'*$0@><5:9B#=27#(01:''F:"2*DD")92>/H3G/5;=2@=H//E'0(!#F*;$)?)A+0*B!F9H(
@r1567
GTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCNGGGAAAAGG
+
+:*8:!/=A3G"!$CB7).1(C-F<.;74D,0%.B2%4*+1G</E:3"88-E?CH;!6>*B:-?/:5/:=2!A48,,9,
@r1568
NAAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATG
+
*"&&+&'%'"$+$)$!%+%&%*%#$&"#+&$!('!!#)'*&#")+$(!%*!"&&%%
@r1569
TTNNNNNCCNNGGTNNATNCTCNNCNGAGANTCNNACANTNNNCTNGCGAANGCCTNNNNGAGAATANTGTNGNNGTNANCGTNNNTANACNTCGCCTCANCNCTNTTNGGNANCCNCNCANGGAGGNTTTCNCNNCN
+
$$!""#!$$"$"$"$$$#!#$#""!"$#!!$#$"!""#"$!"!$!!"##!$#"$""!!"#"####$!$"$$!$"#$$"#$##""""$#$"!"!$#$#!"#"$##"$#"!"$"$$$""!#!$!!$#"#!#$!#!$#!"#
@r1570
NGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACA
+
(;,"4;6#3)GCC:=H==<H"-365@+FF2D<6$@005@@3+!08>B?B4#@+6&2:!6;D''93B'$D':.E&3
@r1571
CAAAGATAAAAAATATGTTATCNGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTT
+
<9)=-@!244,B;A(B!*>%G.+%#1:7<3/37E(,4D"+E>B;7-E)H@E$/5@%E%,;72(,=$-7>7
@r1572
AAGCGAGGNTTTTTGGNCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAG
+
4H9?$=%G=-%C"G+64E,4B.H&,%>>""4(&"':4/7B,<F@3,4#!5E3.,',2B!7<?-*G9
@r1573
TCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGTTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGC
+
H!!!540&,'.5F:F3!:,*%%7&)&.--6/>;;GC=*8986-*)D5D5#76945-F(>;0C!F860??F&<@F<92?/$!0?@:;'EBF,7-E('97:6:('.B/G##.C98:H(H79=8-$2,;@$$E-8471!4(630!;B+))5D=7/D0(A?0<5>8&E,$11$0316G5D#%1H&*654$5(*H+8+G,*C$,(9A0A<$'#=B9:>;!6@'1/)
@r1574
GGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATT
+
6DA$#B.@,+C>22$B:H5>G#!5%9F697=@)8(8EA&)++89@:$D8EE6(E;0<*F'97+B58+)'&-'=BE.B77?E6D6C(C(>4:@#:E#A53#:+?69"((<:8DH=)C-8*!(@(&'<),:%G$C&F=79"2C4.+AC13-$(,'8--4)<6:+*G97G*.''9EH3*7?/$3'<B(BE,+>D8&:0/<(A?&B,9
@r1575
ACGGGNTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCA
+
C+;4<#4F(=B810::(B9E8:.!0$9G5+2H#G<@=6/71??/?=G50=A#5A%'?/D,$;3-4,*-,+&>;CA+4+7(2C*0
@r1576
ATCACTCTNCTNAAGATNACATGCGNCAAATAAACCAATACTCAGCTTTNCAATATACTAACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAG
+
)(!(#$%)$*&#*$((&#'')!*"&#%*+%%(%"$&("+*&)")"*"'!&#(#&#&$&'#*'()"(())&)&("&("#*#&)'+$*$"%!'#+**++*'$+*%&')&($+!#"($")"%(')'#%*)*(%)(%#
@r1577
ATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGT
+
:C+<4'$=+C1'<<9G!.FD=B?@D<85!$A>>G7@;,-=E">G;@85F
@r1578
TACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTAC
+
==0.>'(52;((8C(@+:(CGA%A=(,3H!8=;F>.);==("=+,ED&-=1!=/8?H$&:!7!&*-%6@"==%,0;9G7%AB.>,5A>10=E"5#F?C/&B&>
@r1579
ATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTATTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGA
+
5#<0:&B"F$@((6*"9/=$!#0&*>-=/FC,B2,30>40F&?CAD/-*AD8@;>F5&7GE/;&:92>34"16,18+%5<H>A"E;6E-6E=@G.>(G'>"@=?<
@r1580
TTCCACACCCTGTTTCTCCAGCNCAGCACCGTAATTACTGTNAGCCATCATGACGCCGATGGAGTCTGTCCG
+
+"'%!#((+)&"+#&)((%)*(+*!*&)*!*"%')((+"%&#'$&++()"$%)+()&$)$)%!+&%$"*($!
@r1581
CATAATGCGCCGCTTCAGGATGCTGGAGATCTGGANATTGCAACNAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGNTGTTGCTGAACCGTGT
+
5@%.C:B'6(=14$8'5+EB,6>/35;*@/-;6.6)H!!4D:3G6$E+?$<*6.>D"0(5-4&$8':?E!#C3=?<D!$"2C+#B;-6>FB+@E107,E"@8.@
@r1582
CGGCACCAAATCGACGAATAACACGGGGGCTCANGCTCACAGTCTGAGCGGTTCAACAGGGGCC
+
+@H;#-5;8*%3.FGB=;,)C4C'A0'+H0.37<6H,'0D7H<6F:*(=7.*&'G@(<93&D83
@r1583
AACCAAATCGNCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTT
+
9&'EG6=@/F4.1>A-8(9B591:$A=<H+E%)C(>FA25$$1;30>7>")9E,/%>8B>9>'"@%2$/4G*47GG$D!,H<$9$24+CA>8/?H(<<15/B<.,H/9@2B1-BG,,2"%F)?$4"B5,H@?D*#;$:#70@,30..?'/CHA+#G96
@r1584
TCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGNATCTGGCGGAC
+
@(=##B%+>-?E6C$'B1*;/(/.+*C3)'4/.7.)$E8*>D&GF!'!1C,)6%?#6-(41&8>/@#6(5+8$EB01@';F1C*+*DB>1C+@ED9=-%;3B2''3,:?@A!5/*GGG>462=!.$-B=(-?>:'<"9B/($11<%&%'
@r1585
TNAGGANACGGTGNTANTGNTAGAANNCNGNCTGAGTNCCTACG
+
&#$"#(("%*#$*#'!#("$**%')$$'$)+*)#!"#%)&"!%$
@r1586
ACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTA
+
3.71:=:((1FBG>A'.'%%,.08G0=>8@+H+1CH,4,#()4<=B58<C83$,,G=(="!7*7>(8D<2B6+0"(!!,%"8'9#,<859&/1A-E0F53/"!:7574BB7,+1?51&EB4.<2'07=EE=+#DG/&B:692F-2.CE#&3<D#0:<,3+0'C(:,'H*G<B,A,02F*A'&&&%<?4)(>#4="F0.<*!&/4H2/5G6@5B/9$*=F8>;E<22)*"+/)#)'4
@r1587
GATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTTCAAATACCNGAACATC
+
77+0"-4',C)G::153F!>,>?7;;)(;"*2AA+C/@8A".>D);+4(@5?+,E
@r1588
CAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGNTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGNAACGGAATTANCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTNATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCNCANGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTA
+
12$E6.!=EC"!"%")<7">)8-,B,4B-5>@4@;4<2,>41$H28G<)@;@@8<3*4HA*4"F,A6?E1A+8CAAF(%:(&G-0B,/4"9<@>))H7(+'#@B9+@>D)%@;7!.51%,F5!=H$<;$F&F<5C#211GBB))3=8.B&@,A:A"5)2B*G7E0(/F@@-!-07E&5H'HG.*H9F@*<86??8G8F-'G-H@:%7GB2-%%B&).&')'06:@00'#4=13@G!632,E'))?#+$&A7.*>*=;$"H/'E1C/,$B0G!(:(36-%$(-499302F;$@3CE(<?1<D99'!<02"!3AF'*HB&>;D*#<;3D!5.3:'A8-#%$@;0?,1#.)2.E;1F5=A,?5&$H/33/0A).#=!D+E<5/44AA8'!8F#A
@r1589
TGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTGCCGGCTGTCGCCGGTATTGTTCGGGTCGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTG
+
,G82+2&G27C8)9G&/7&2C)..3&>B-(;1D=4&/?9<%/,<G@D?(=*24B?;0D$#$?$-A&6#5''(F6GF8F>E:52A9</FG&;7<?;1FFG;/?11.3=!8-6*/"B'")(!$%@"664G&6$%#6#+H25(,B;F3;G1%'8EB2:H'?'G.&8+%%28/ADFA)+7:13.@6.E%4$A,=&;+9F;&,!G?
@r1590
CTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCACAAAT
+
"*DG:=E4B92(B$,34,$;H'D,GHA21%60"3=</CD+(,33?&=>=,@+:&=@%+5>
@r1591
CGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTATGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAACTACAGGCTCCTTTTTTATTATTNGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCA
+
;A@?:78.%<=.!D=$H0F<*5E9-3<=?'H$7:@+#,1F@('GAH2:FA%H*B9H,/?<?D2ABB$2<'!@'-%"@?A;<$#'0A=E.E-B!'%H6&96GG1:9?)0.2*4&3D5.9@F(5!*GE5+CD-3$$F0$:)%#'(B!<,C0!61;4H(F8D-8'12F"H226'<>#574%3.+51F172<D0;C?"G2+0-/@9CE-<4&53#3
@r1592
TTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAACAGTTTGCCGAGGATGACTGCTGCTGNATTGAC
+
*<$>9C1&"4!'F*%,6'%(E7EG<;D1"B24.)&%20,&+7>?6,77GE?6B%1@$DG:;C,:#!#!
@r1593
ACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTAATTAATCTGCACACCG
+
>+HB=$DHD8-<7F%*:0%9836)5D1%:(F3+2'<)"#.1DA7H6C?1D7,8,;%6;6G#CA<&+A=#,%9HEC:#*0,0C+'.2*.4BH.)9!38HG:01:EB:FA)E6#+'=!B1%A;>3>;
@r1594
CAANNACACGGCTNACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTANCTGCGGTCAGAAGCTGCATG
+
%*(##%+((#))(*%+&!'##*(!%('(#+%(($!+++$&&("!+*%#&$*#)'*(++*'&#)(&#&#'%%+#(+(!"*!&!"!&'!'&!)#+"*!(%((&&)!!"!"$))")(#)'*#*'!$%'&)'"%$%!''''+)*$"
@r1595
CGGAACAGAATCATGCCTGGTGTTTACATAGNAATAATTCCTTACGTT
+
).E3&0/@DF;7(C;,+3;7A*&+-#6,C.@##&&/$:H="G%H:%)@
@r1596
ATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTG
+
/01<&$A@;?:6*.!-B-'-@7.+!60;4><%E,DB)C<8/*(3!
@r1597
CGTGGTGTAATTCCCCCGCCCGAAATNGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCANATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATC
+
9#%8D.@40=$3+#8B1=*F)-A%:26.@C*"42>6;&").$G?&<%5G;%11$2,25&52,@(3H.!'8,8-$F*'90.B<5<!*#)(GF>%5<*4FC'7:H0=6&.B1BHA5&'59D7#32&'+9(D<4F=>6@*G$A=;)F.E4,,.4%HE%6$0H
@r1598
TGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACAATGGAGGGCAAAGAAG
+
0,A57HG1%)0"8#/)F<,:)+,)AD'*0!,AG"/1?!1'8E":E&;;F+(!:G"./,$A,37)911;#D(?7=!94.9B%=9"+9(7"#%'A8+AA/
@r1599
CATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACT
+
@%'>2#""#G+1H9>2G2>>3;)-))E=F;CB#7A(7'G<%AD2@G2-9E35*EC
@r1600
GGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACG
+
9G7%=,?3($?/38(*8-F)&B;&,(=$440G#;*5*,0&/24'2<<=.:2=91B;2>D++:8?'F7H3,@3B"23:7:?),*>D!=,5$3A+H-E9&1G
@r1601
GTAAGGTTTACGTCCGTTTTCTGGATGCGGCGAAATTCGTCAA
+
F*2,E7G/:F&<!9)H"2(@7#8&A>5"8A2F=@#73:<*'-)
@r1602
CGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAG
+
9B:2;H**?7.):;&-9(9="$/,-<C+9!+>74<=D-'2:1!-5A&-;$#;@=*252"#'1'04:H/<<(HFB85-=DBHA-001<CH9;C?-"#3'=;-0?H72-.$B'G2B.8#E5<//5%?34@&1F;+0"=7=-F#:44F@$&5-;1/B72A%76-%";(5,"(8(1#7D9E@>2#F=#D2#'$"+'>6A6+,-/B88*4627>E-75!),4@08'31,$*&
@r1603
GCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTG
+
89219EA*GH>=",G'0/,=*CF)6G>E(/-8C-,>=69(86H-&
@r1604
AGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAG
+
1A+8(E#=*$$*@&2/(1?47*+89$'/G*2BD(:?H%8*82?!='B=(*:$"8B8-E6
@r1605
AAAGAATNGGCATGAGAACCGATANCAACCGGATGCTCGTGCGCACCAATACCAACTGTATG
+
*)&++$)"&+&)+%*#$%&#((+*)%''#)#!+*+!&!!)&"+#!$#&+++"(&$*($!()$
@r1606
GATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCNNCAGGATC
+
5.:D9G:A/"+C8%'0B;'4!F";8:=1CFH,25"1-9*6?A+=:1>D%.86&+*
@r1607
ACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGANTGCCATCACGGGTCCAGATCCCGGTN
+
:9-67@8B1.3"A#9;G)3!/<&D"&<D1,BCFC3.73-BE*:%68*6'>2H*4,$/,>=.306F-+H+.#'%"6
@r1608
AGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGGTGTTCC
+
38HFAA/*>5/?,;-5#+8@!%+;"H,H>4;EDF@"?/.40?4%#A5
@r1609
ACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGANTCATCACCATGNTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACTAGTTG
+
;!-%57B>B36..A?56,<>H"1%F(/0=$C4047D2'!6/5='"E;G7-6>@0;8HCH@<D:7<G4<0*4"?B.@H+?<2>8'+':D-B!6.:3$2G7@55.9
@r1610
GATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGA
+
HH)?H+&3$*-57<F79/2!C75!:/!'?8<D;+7G(66=
@r1611
GNCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTT
+
<+(#B:F;&1?E(,30B,;4!E(,(>H07E4'2C%CF.9356$6"-8:()=;$;"-"-EG>1F)"D>G+2)=<GC2)&5*E7;<:@4!;2".!+2;!C08B0&=88E2.07((<$EB*B%/%G<1#
@r1612
GCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGNTGGTTTTGCCCTTAATGGTGATGTC
+
1FB;65E-3+'*D&->/0F>E!#D')26:&9*6F@+=>622;>*,C$.HGE+:+6A.$,0?D!7??+>0::)'<*G-'F%%&'C8-63&!>
@r1613
CCATGCTCATCAAAGACAGTAANATAAAACATTGTAACAAAGGAATAGTCATTCCAAC
+
(AG<5"=1/:@!0"F&?9F+5::9/=E%GB8&3=3$B.=D#:0GCD;5)9@088-"-,
@r1614
TAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGNGTT
+
(C<+/=4067))1#>4.0$-,/D&E-(23"/)@1>DH!+.@,DEGH>DD5B#+/;C'9G@6D7;>50;='%?&*6*+4%H$"FD&$
@r1615
CAAACAAAAAAGATGGGANTCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAANTTTTTCCATCGATTTT
+
FA1/D++':6F.1@&4;;H>/E"(0"8>'A<*F&+=30<=C5B190H4@-0.+)</9>$@BH?@>/9;;%3&F?)<$(H.,=+;;$-@22E.6778AAFE)F'D,/HC;(*<BFE$(<DAB.F&G?C3$-D/3GB<1@2;BF0/#
@r1616
TGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGA
+
/(*6,CG@5/@#*!7'8*-8'C*?A53DH'=8F0:-5&:*5.(BG/C$$C9G@7H,H*
@r1617
GAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACANACCGCCGTNGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAANCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGNCAGCGACTACATCCGTGAGGTTAATGTGGTGAAGTCTGC
+
,2=A-G4</#%5,B:294%0%D?867G8FH8F94*9AGC310.;7:!%E'8.9:FE%"/"2?6EAF8)<C9?!.&!8/C,'1.@F;..#/(7A-"A(=%?H&>B0",#*?'?G.#+:FED'E3<7:(>?#)*C%/"#7$0';"959)4<10?6!&)A9=1':<"4<9B<(B@2'1A6")7*G#>!'9@35@BE5"3A&8">7%#3*G$=F%3E=8";;*6"6;<D)-E+8?$!$E$9
@r1618
TCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCA
+
<3BD,%(@'D'2,C!E(/%.49H$&A<E<A=84><?+>*6!*,2=,D=3H%75+HC:-B5.(/:>*&2%*6@F)@#D?B")))C(4BE0
@r1619
AAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAATATATTTCCCCTGC
+
9*%73/1)-/CG1BB!:=%86<'+%86$)1G1H<,.(<G=1E*63CCF.!G10#>,D7AF7/(=79?9G70C8"?9,20/)5?H)H88@-E*8+D"6->/#7)$)(+014:B0GA
@r1620
ATGGTTATGACGTNATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTC
+
>.@,(E4(>FD9)!:%DF.BH6=HG@*@<0-,E)C+$=;H@69<#?=%B#HH4$!(=D<*&4F/<<9A
@r1621
ATGGCGCCTTGCTGCTTGATAATATTCNTTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACAGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGNGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCT
+
<8D8B!9.6)-:0&G:5G(;9.:>96E)!?!<97F69</2G2,A5-/G6F"G$$$2#>!D4:"%?2",-7A7!4'BB634%3<:7"(45E4%8:"&5B?H3EE1--=8<F'A+9"D:()A/*#(GC5.;5/):!.679+7$B,B:!/@F!0B<,9,D@/F0=)6<B=20<4:45*'B3:%?H8;@&!'E&E!;.E>$$-G2#H584AG@:17)$3B56H,5.B-&,*3=@.41.FCC-)H5*!0B#:'3>*-D)H.4-97>4=9$E(#G"#FAA/,>!3-@**"!
@r1622
AGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGT
+
9,$FD<,)>0%-E(DE/6=3;;A?,)24+A0&((C4)GG=>8
@r1623
CNGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTG
+
6$4?/()$97)72C5B!A-77685A*GE67>/C/7D&8<2"%>;<#?;A5$4'/8+)>8%-:54D+
@r1624
TAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAG
+
'6+51/+?.@&,;)H7!3GF&"8.51:D%=,HA=@09;?F4?;2:)5+1/%*?-<CB00)2+H=&#8":D6,B$"!C,%=/F&7!EDF8.AG%$8$:&=229@E("G(+C7<FH1>#B.5A;80+;,HC6&*=,A<A880>D=>&,2=2$7-HB.D1F?9./B!;#F,*HAA
@r1625
TGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAA
+
C*(73B5B:&-A>918A*">C)')C?G7H0!H0@BE)(CH,:=AH:-$6,+?*130;:B=9?@4':<DD5FG(H9A9'GE8E6A;./1#,:"&
@r1626
CACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGNCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGA
+
+#+#*%$(*&"'')()(*+$"%)'%(#$"&&*!"$*+$%&$&)'%''+!%&)(%&)&&$&##+$'+#()&$*%!)!)$"%$)#'!)"*()'%!'"&)()#%$%)"!*&'&$$&$&$#(%!'''!#"*!&+++*)+%""!#"#(*$++"$*%#+&#')"!'#+)+%+#*&)*!'%!(!'('%(($##%&*&'"$$"#+"*##&!##)!')+"'&'*$((*!&"")'''%$")&"('$"$$+"+)!%)*)!$#"*&$#&
@r1627
TCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCC
+
!:2+%)/C(@.74<3!@6B#C7.B6A-82=@';%,0';0#F/%'>E@13&!;0>87.4
@r1628
NGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAAT
+
'A&)'59+BGB/$&GFBB-4?5&B2@/51A*6&"4)C$52@,'$)7;>>-4=AE
@r1629
GGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGNAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCGGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAAC
+
"7"45)"<6.+#,=:;4+:4;H);77B!A8&5$5"=!&?4+0%%'+0=G(+#;D5+DA5F41693+(:DC?1!#"!'+'%28B/*'=969%*&)=#:5;)/*!GE<:!*5<"8)GD/>C(/@A'F8*.8>.E8+,)D?:.DACFC$00(:H''1#;37"6)"07GH3(-G5H.#H=,(%=.>!*D;:?..'02@?++@<;%
@r1630
TACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTA
+
53"BD0E5HA:0=C(=&/$'&7<BH&'/75G'GE/#E99)2
@r1631
CTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCTCGACTGGCAGACACCGCTG
+
&"++!%%%*#+!$()%+*)(%'*&"*#$$+&"'%)$"$&)!)"(%&)'##))*))'%##!'&%&$*#+*"%+("&)!"%'*"!'%&!")##'()*(&+$'!!$+*)%%%$)*+$%*'%*$%**)'&(
@r1632
NTAAGGAGCAGCGGGAAAGGCTGACCGGNTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGT
+
&%!#%%**+"+!$"(%&+*'#(#"(+()!%""#&)'(#%*)#!($"+*!"()($+&%+!'&'(%!&(!'$*$
@r1633
ATACCTTCATCTACATAAACACCTTCNTGATGTCTGCATGGAGACAAGACACCGGATCTGCNCAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATT
+
20@!>!CG(C";*E$%=?.0*/F>9?A;3,?+,G%::7GBFE47>G1//)-9F?;EG/15+F@H#3(=E=?HD-5B!*!9$237.$;42@=40=F+#!1A%7,#(@"
@r1634
ATAAACCAATACATANAATGCCAANTATAGATGAAAGACTTCAGGTAATTGGAATTGATT
+
:(,ED>B)+3?>2,%)E"$*,.:H/2,8?2HC3@B8"7$57F(C9.:.53/0(?>85DH"
@r1635
GCGAACCAATCGAGTCAGTACCGATTTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACT
+
%$+$"+**$''*(!(+(#!%+*+%)%($&&()#("''+('(+#!+(#%'#"(!*")%#"$*'*)"++
@r1636
AGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCNACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTAAACGAATACTTTTNATANGAGGAGGGCTGTTTTTACANAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCANGCACCG
+
$*<##.!B,5*%5.A()2;H=EB94)B265B>)G=/#:CF+D9,HGA$0'2"@.64,>7B"G?42:!4198C+*DD0@#E?1A;@2?->'<A(*(>**'9A5:8#E#:'78;1%#;<%7%:-.;%.>(5,&6)H(<)#0154--&#424FH8?FG7B/2A"@#A03DB!%@@B9==A+=<@;CEG3ADF@B5$?'5D(GH=47!9?432.1!6>.>9-"'#>CC;!30/B&/2%G9D24*8*%HF6/#$-C+-/<A>3;.2*F',+%016H48B0G2!?H?47@.(4@(7!2B)7D.#H-#EC;/G)=">0ACC)A$>.=@9%3H>4<8,33"=+.:+<352B
@r1637
CNCAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACNCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCNTATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGT
+
($;!/)(*C83:ABB41,AE'79E5=@5'+&*$,-1/8D)2(*?@E#5(FA1.'.<1F1%37:3D>1)9</,&$%>,+.1.,0<!D6*5"++>3,#C37)5445C40,;AE+#106?>;:&>#:5#2.-%B8:D#'19,"D.(/+D>F76="487,>B#3#(&9
@r1638
GATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGAT
+
1-53&#D;#>,E$E(?<:9(/3'"/=B&,A#CFE(CC*E&2C":%'*"-".=&#?*@B',8B4&@+C!.0F585<'
@r1639
AGGTNTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCG
+
D67<F+..C$<>4'&H8GHA.EB(G!'G:2E;&.CCA*(4F&"H-&;$-,E
@r1640
TGCACATTATCCTGAATTTTGGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGNAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTA
+
)+G.80D*A4?'D+:#>D4*@;0)@/C8(<D@.8F,%*,9,(.?G3?;:9,D66/$<0!9!A$#6"!)@E$&!),6.*"G!.D2$27=*>DB<":(<(,DE;"88,F.$=)95'@-@#%82<B
@r1641
AGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTG
+
#>E,(G82'@G9A<"+-+/1FF7B=507D0-,-B8!@+D*69?/'F7A!9,0?9@B9421.A=F"9)@6$."-./G-9@F7.-F-1(/79F!:@E'$:4:66=4.C$:&
@r1642
TCCGTCGTCCGGGCCGTGCTGNCCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGACATTCCCCGCTGTCGGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCA
+
:G>0",-%=A<%.-CAE1DBC0"D%/2)9(07--:#?BD:/9%@**.BA*C&C+#058DA7%253G*4H*#!"@F3D8A)'#D=&EF(5!D-<;&,)<H</"4"4H&@E,:!.&(+9A*"D8?'*)6*&BA+!28,3?(.",@F#5!"'EH0-2<!/.$$9=-*H<+*.("'%#'!(37D38>3%2*
@r1643
TTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCNTATCCCAGGAATCTGTCGCAGACAAGATG
+
'+H%?57F8@'.6!GD9E7BB>30)23ED&<30<G9#!<>(5B$/(-&G?'0HFE;0@ABE0*@=C'D
@r1644
GTTGCCAACCAGTTCGGCCNTAATCCGTGGACGAAAGAAATATACGCCTTTCCTGATGAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCA
+
B*E-7<$5<G?!CE#3=974::-8B.E,6G==D%"H018E(86.9-,4@.:=>B/*$33?4)%BBF-%:"4#%%D5A4)C!3B83);>G*6G%'$>"!936-:"H@7>&AF&1<(?5,=#6:;FEF!:=4'.-40=%FC--&H4+F%,H-%7B'(20-6HE!?06D":D*&;<'DA"&<&*!;G3%8#D3;+EA@AA
@r1645
NGTATCGTGTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTNAAAGAGACTCTATCGTAA
+
!++#"!'!"+'!(&$()*!$&"$+%'!*'"**$')(%&+%$#(&%*)$'**!($$(!'!&(&*
@r1646
CCATGCTGGCAATATGCGGGAGATTACTCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGNTTCAA
+
+1B$#%*B(H#1C#!/*/=".=;F.04@:H<1FD89>25!E(#FH?<1$-G*>FA*G<"():;#/*/,3.:8,A2/4G9B7>
@r1647
CAACAACATGGCCTGGTGTCTGTGGGATANGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGT
+
H=!%7A=2?86E/8/5"(&'0#8"600"%"<=67#,;4%2;*>*F/,14H+F?*D<<G8/9F,65F*/6+F9526$E5>1D9H%53,/0DD(2(3:A$
@r1648
TGGAGTGACCCGAACAACGGCAGGGAGACGGCGACAGANCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATNCCTTTGGCTGTACCAGCCGGNGGCAGGCACACCGCGCCGGGCTGTGGC
+
;)E<*#.H;9>!4H5&:C?<"CAG<&3'(:10.E<D(.+6E,;-'7>;$E(,?0(##/E84')#<2?09A..AAH(#0!EGA</A4;)%A0?.H,-./F(5<!CE2A::H3&C@,E1B/G-*'A).796@7=<C.CE*EB'2'?/
@r1649
NGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCNGACAAACAGGGACGGGCTGGAGCCTTCA
+
$+(%(#!$)+!+!$%"+#"%)$$"%&!&)%"#+*"&"!&%+"$$%#'!#(+%&#''%'+%%())#")'%(#"$
@r1650
NAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATNTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAAT
+
(0.+0?2'$55C*0C+?>?FC?G#2*A01/F<=;C8++,7/8E'5>D5<$G:?!#&F$A'%1&14&HF(!3!5?+,37AF%#@2442>@&3H0C(>?$!%0+/C"=,
@r1651
CGTTCCNTAACGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTG
+
B?/"<.:B<-$H0/1!08/;$C>EG9@$)88&4*%7"-</@1AGC%7C@*28$?)6&/F-6,>+7A!%%;<"71!$+B@0F#)B
@r1652
GNATANTANAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCNCCGGATNNGCGTAACTGTTTCCGTTGACG
+
'&$"(!&"$+$&'*)*''$'("&$'&$*'(+'*'+))!$))#)!#*#)$*%%!#&!%+#&""!*+%%#+!(+&(")(*$*#$)'+(&+*')%"+%)(*#$'((%"%
@r1653
CGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATG
+
;H3A,BCB:?(/=D3.BHF"$&:2%C3+#&HC-HG(1@?1>=
@r1654
TGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGA
+
>7>(*<;5!=:%A,':C'"E,C88";7'5"A-%6B&!E)0G&$B:;.+:.-!%(EB71H,4EC%+%>=B><1@)6F!7:=8C0G!18>
@r1655
TCGCCTTCATTAAACCACGCCAGCANCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGT
+
B=H6+0?2F+/'B6=9=6,6$FBG35+5H(3B93375G(.3(*$A$5DCB3;)7G(:G:*F5<AE
@r1656
ANAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGG
+
%!F&@,>%4;"8G7);DF))5D82,8B>9B)6/F,9G$&"5+G6
@r1657
TNTGNANACTCNGNCTNCNNCTCGNCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCC
+
'$#&!%!($'(#$*!!#%)!&(#)&$*$+&'%%)('*(+'#*)*'#'+$!+'&)""'&+!)((%$%*!*($&%'*(&"*$!%%+"&&)!!"&"!&$''$*+!$)
@r1658
GCNTCTTCCTCCCCGATGCCCAGATANCGCCAGCTTGGGCGATGACTG
+
$'!+(')'(+"!$&)+(!()+%"(#+#("+!+!+%*$'%%&$#)"&&!
@r1659
CNCAAAAGAGNGANNCNGTGTTGCCGCCAAATAAATTGCGGTTATTTTCATAAAATTAAGGGTTACTATATGTTGGA
+
&&"*"'&&%&%#*#"+'(+*%*#++%$"$$)!)%#+!)"'%&"#+(&+&#%#)%#!*##!!!#($''++$+!%$$$&
@r1660
GNANNGTTGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATTAAGATTCACAACCGGGGNCGCTGAATGATTTTCTCANTGCCATGACGTANGATG
+
%(&$&+%!$&&#%+%)))"#$'"#'#"")(*%'&%$&##*#%$%%"(!%!+*#&)+"#%+&!)"$)%"$*")"++")#!##+&$'++"#%$!"#&)&&%'!++*%(+$&!(%(#'!*&+*!*"#!%'!"+)+$*'$$#&(&
@r1661
CGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAG
+
,F*5F5'(E!E9C>3;!92B4):11DA1G$%(!8"C86"*)0H&C2=9079!75(307:A@B";1-%":0!G7;*"'78@/$!8E%718!23>G-/;5!$>,&4:0&8FG?H$C+0&6)1H=A5>-&@>5E&.3-HA)!*?:@
@r1662
CACTCGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACNATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGTCGGATCCCCNTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATA
+
(")'+('*&'(")(**#%*)&"!)%$)%)'"*"+##"+!*&"&*!+"(*!$'+()""**(#")+(+"%!(!*#&)%$+('&*!!#((%$+*"('#(%)*!"&&#'))"!'('*(&'')(#($)&"$#*!&**#$"&++!*+"($*&#+(('"'!)*"+"$+(*(%+'$('$'*$$%%&+*))!$%$(&"+")%+()))&+#+##
@r1663
GAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCC
+
.%6@$G&C,1",&380G2,,$4@-$2'5H3>$'.E9?F:67DA-+(E$$"A&E/84)
@r1664
AAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGNT
+
-).?=?H+E6%!77":7E)$117AGG5F''G71"A6C%:&C/6471(+#>9=7HEC!G=8&>&8)1*35-.*9<>C/;23+."*
@r1665
NCNCGTCATCANNNNCNNTNNGNTCNGNTNNNNGTANCGNANGNCNTTGT
+
!##"!#$"#!""$"!$"#$#!#!$!$"##!!$$"!!###!"""$##!$#!
@r1666
AGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAGGAAGATAAC
+
:E1*H9?@6;)9?7D;((25<1*A:C9?B"-$?$FC/4@D#?'"A+9.8&9F
@r1667
NTTGACNANNTNCGCATTATGAANATGCATNGNTNANNAATTTGTTGCAACGAACAGGTCCC
+
!*"!&*!(!!("!%**!#%&!#&$%"())($(!(&)&"'%+('))%&!++#&)%%$#&%')!
@r1668
AAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGT
+
4?3"-$F#DAFD>,D8&!G@6.1-H)-4913BA/)*:%6%-/@5AE5(3-FC62"%;1/C2$03A486%<;&'>>1564*H897H!:A+C#F;9<2H.>@"=/,38&G-D1B$C42A$!$6/>?@D<3%7;>0E>
@r1669
GCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTC
+
H(!0>>D*F.B4&8&$%+H4/:B,B1==<89;E>@DG"$D:(3(&:4+G;2D<;$7A317F"-&=E2@59F5
@r1670
CTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAATTAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTC
+
=BF))%;?-&>EC?.;-#2H0#AC+4)3#7-,A/&E'@C;"%+)0:<E'#G19#3.6B+"%FFFD5(A+:D)A76F/*8A&9B+A"(H9C0$H'3,)5C89=-"69+)$@&8307!#FDG=*?D5+//HG/9:0?".;$D;!;D./A@:C66;$70(4>8&#'=$
@r1671
ATAACGGCTACTCCGTGTTTGAGCAGTNACTGCTGCGGTATATCGCTGCCGGGNTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATT
+
<8E'D%E1+C,-&C8;6:.9A=#>A8G>@8<6?3&,9.1:6&4C$2H1AA3-@5D"*=)/*E.7#*&%F@.D"1D&'+D:7*<649!
@r1672
ATGCAGCAGCAGTCATCCTNGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACG
+
B&H9BHB>54>G6?<"C!?6++.)8<"+.2AH5(64;4B#8?,&%3G#H?+C%$29=9.2$85@5
@r1673
TTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGAT
+
H==758E??#+#1&&&B"E9C4&GA-6B3+(;H3,A&/E6'H@4,F=*3EE"=DH**);1F8;=*B<8'-!H8*14-)F2$F8@!B$-@6B7BE?!7F;6D3)1)1-F2&(0B7&B5$%E3-A?+3&.@
@r1674
NGACNNTNGCTCGGTGGGTTCCNCGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAANCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCNTACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCG
+
"#$*!!%#'+$++%+%&)%($"+#*#*!*)++(#+%)+''+*(#)#'')&!+&'&)&!!!("&*#)##$!$'$#+&#$*!#$(!!"#$*%$"+%*"+(&"'+$"%#%)#*'&$*$##)(!**$&*&%+)+!#!#'(!%$'+")!*#"&%()*%'##&%$$$*$$)+#&!"&(!!+$
@r1675
ATGAAGCCATAGGCATTTGTTATTTTGGCTCTNTCAGCTGCATAACGCAAAAAATATATTTATCTGCTT
+
%/*#=?8<)1.F@BH)39*%E14?<;F3*9D/:5#5?D79+-8#,9?('0-6&FD31-=@,D$B8)#$#
@r1676
GCATCCTGAACCCATTGACCTCCAACCCCGTAATATCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGNCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGGTTTGATTTTGCTGTTTCA
+
-5$C$0A(G'9%79"+4;2$$1FC@&G&F+?#4C>620H>*30,49:.>2&&8=G'6E2*=(7&3'H:9%"F@;AD8?'H!B'.6>>&$/B$5/A;*@6D:>>41=8**:234G$FAA'"+1))F@)!<A7,?-C0'B>*G$%252,;?:(>)G;,EF;D#465A9'.@,-HE@E:H?.;0D,+:<2134#*+;5+A&#0+3B-+&&4)@:3*H#2-*7%7A-F-5'.<'3E#*5#-4(=/F<F48D9=#%!D=@+-&,0-&-E=-./3;.C=+//7D#
@r1677
TCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAAGGAATC
+
26;&<72F>"0&,&C4F<0992CGDG/.H$,&1><F9"E$$D7=49(-,G7,>9)%)HD2/=*?3H(@0E24CA<8,:B#>&>:#53H*;HH"&%5%C,GD$=(
@r1678
CNGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGT
+
%%&&*+$%+()!"+%"(##%*+')#"*!((++!&$+&+#'+#"&%(%
@r1679
CGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCG
+
9*EFC(;03+'2B(A@07B0C3!-F+;297$F0$*?.+3;-#&E:<
@r1680
CACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTNGTGTACCTCAT
+
A(,2G;A)?0%(<6&;8"1#D%F%A!6:=%>86F=+0C*E7@#'4;'A<A5C"&
@r1681
NGCCATGTGGGCTGTCAAAATTGTGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTT
+
!'++(*(#&)%!(!(+!+#(!%&#*)!$('&(&'!!!""$&))*'(!+'%%$%#'!%*"*!&+!$%%)!)%!"+!)*(&""#&*(#*)*#&*+&&$)"(($(((*"(+'%+!
@r1682
CCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTAACTAGCG
+
+AA(0*1G*D'34H9G)6,612E%+/G+*;7.<==9H$?(0;&
@r1683
AAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAANACGTTGATGATAA
+
?6G59GB'-2726/:D@/D#(7G2;%3*274D>F18!@$'8+HH<G=(0*1E/$H&"/'<!/(#3&$:5+@56/@/A&<
@r1684
CATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTNCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCT
+
A/H-4G8B!H-A6D+BB6E?G,A5=4AE*37.$%=5/+):->');ACG7)7DB;)-!-@*>GA="1B(EE+%(%F;/4,"(DE<+#:'0-D?H;=#$4.A$@H22A)"51B7@(&:EC4.&%8G!7=;,A.>=DB:.00H2)=(,D2-4&""4H46C3=A22F'#$H/$=3D>@?;??'=
@r1685
AAAAAAAACCGCACAGGCGNCCTTTNGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGT
+
);,3=<%B!'F(A!51!,>!G0""E'-<6A=2+<H=G=$-E#%!@8H"<A9!#7(%D'/A,.*$!B<=F)&&:D"4*=
@r1686
ACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAAGCGATCTGGT
+
BC=AD167;(2D@D,.6G:G!*1(EC332+?7%,G'+%(5AH+;*6,920D>=$0='=1H96-##576B+"6A-
@r1687
CAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAG
+
7H">B<>&<B6@%."=#)EF5>"B2)$%?D=1F%;A<#*6"
@r1688
ACCGTGATGTCAGCCTGACGGGGACGAAAGAAGNACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTNCCGGTGAGGACACCCCTNTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTNGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAANGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTG
+
)D&E&!21/;E+(%5,:?.>480>/(;9=6&4?+6**&=@?/E<<=!+D0:4409-0D.4#%.02>)<*$$6A8:+#D")F(F#G@G&341A4'?1#"+$,$$-*$4A*63),8D@821*!H@F>E<2)B0=;"/;#96:@%B#,'"&/"'(@$EF+'A2#C0E"25FC&E4D&@.2'7DC1C/7B%>*A#-5@%.F2C6.4!'9:*570?4A(>&>F8=C<,))69E.7EA?%;H3BC,A=<C#0HA$5G@5C3'"<880@D-(*"#'>"G28@AF/D'%1:.$HB!%DH44)97,(</>G)A<23;&D2?AG7+,0.E75""#CC2F#!6
@r1689
GAAATGACAGAGCGCGGCCTGGCCAGAANGCAATAACGGGAGGCGCTGTGGCTGATNTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAA
+
G=0;+*+03";3F-D$=.&<(<6('0>3$)+$,%BB3"?D@G@>>)5-.!=)D5D:?&C>!6'42%2?#<=)47,0.-AF1+?7@AC,9)H?4:-=.?
@r1690
TTNTCTCTGCGAGCATAGTGCNTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGNCCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTT
+
$$!(+'+(*'+"&(*+'#)(!$'!$"$"'(!&%)$"!#!+!$*"(&!$#'"$(#)&)(!'&##'#*"!"+&)+"(+!'$#$+*)))&)+*+*$$!+$%'(!()'"!$*$*#'%+*')%!+)(+'+*#&("(#"#&*+$*&")&$%#&&(!(*&('#'*)
@r1691
GNTGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCTATCAACANCTGTTTCAGCCACTGCTTCGCAGGCTGACGTTANTGACGTGGTNCCAGCGACGGAGGGCGAGAACGCNAG
+
'&+")*)*&+$+('+(%'"$*%+&+#'+'#%"#!!&#!$"'"')&#'+$$&!"))&+)+**"%$+$)'("!'%#!'#&'"#!((")&%&*%+"''*!(!!#*'")+"*(%+##)()"#(*%($&$'!$
@r1692
TTCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGTATTTGATCCTTTTACTCC
+
#+)&!"&$)"*#)")+&&#&$*"%)!&(%#$"%+*'%')&"&)%'$*+&)&#%#+($#**($(*'#!(&#)#%&$+'
@r1693
TAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTG
+
'GB?&";!F&2,!;+5D2C*3$65A9'#>4;5@@CH0&$F6=!1$C,D.)20F
@r1694
AAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTA
+
&-F*"#-6'D#,2E3*"5)=1&8&4+B9A:E9C:#=.!>C!);/3&-*G$F+1;EF1&>/0F2(@%<+2G76:'D*?>=+0.%A?
@r1695
TTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATGTTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGNTTCCAGAGACACCTTANGTTCTATACATGCAAGTACAACATCAGGGTAACGCATATAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGNTTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAAGCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGT
+
:7/<0$'54>"D+A<)$?4)+/B0$C'H0H489'A*90C;$A+'FB;3-F:?=:*7)(25A>=:-*:"#0480"<'B6H5HA=%9&)"!&<#-7"=*>/*C>2CAEBA&-!/B-0-(27>7';7&&#GC;58#BG??!+//3=8)-%,H--1')"EG6H92'*:'C"A"/)(-.$D-)8C-,>>(:>37?(/(-(;%F8;+&1B07H?DC;=)616<(7-BH0)2=E??'9E@!?H9)!0.)E?$A)=-1F5%<6AFH3B72BG:=&;$)"7$;BD%?&H<!!$</#"'&;?F-,!@2*9&4C%,:A;*(..5@$HA0G-!>3.FA1$=)+:B5
@r1696
AGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCGGGTGGTNGA
+
&A5!"**?B9@EE2%"D/'2,A"A1B,'?B8;D,"-7CE"1GE8!(0B#6(
@r1697
TCACNGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTNGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACNGNGGAATGAGTTGCAATTATT
+
($$#%+('+!%("+$#+*"#')&)#%!%!!)%)(*)#'))))&*%%$"(#!$%%$*&+*%")''%+"!&&)%))$&"&'%%&")!!)"%"$"')$&!$!'*&$"%"*')#!#++))!*#(
@r1698
CTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCG
+
HDF->0>'&':./$??85GG@(00F-B:E8?@1'*3.+F.
@r1699
CCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACAC
+
/7=$:D?6?E&1&H==C4;&4,(:0CG;(#"@*'%4.%A7#3H-$08)H":4+&A@*A-"7C-7:,2./E,@':%+?)(9=;-:E6B/BB$C=@H+G(5D$!),'0,0H!DE08""2(6!6F&;2$,C01
@r1700
GCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGCGGAGCCACGG
+
E'<A'2?&:'$:1D;82GF-51+%>&&.59?;1AF0A;7E74,:0C$)97A=G$'E*6*%858!3B<#'%!E*#7+D'F'D</-8BA6116!HG0D86;2/"(.G9?"#/+@G&7:2;,'%8+0>E<A*56.*E4*4.*:!5D%G+>+A3.42?F:C%1@3=!B@E92A5;@'H.15+B!;D15&#1C"/9'@
@r1701
GTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAAC
+
.'+'#5B72-H65-%#>@'G-4!DE'B6,=BH7%%0$<F<E(E#4.88@0,#?$*
@r1702
TGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCA
+
4:@A:$*$@?H,.'>C#@33!0)'">-'=-';?7%>-'>50!;3374'3D6&9;9HD1?8A-"78HA$$5#5'8HB"#DCG0>11@(&?(/H
@r1703
TCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTCAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGT
+
1C-833)>5$5E6>(&@H<%@=6A5E66BHH#:F3A+48@93%)@3;E):H30;,.+G33*&.22/EE3+G'.122*H*-"645&=A'G,%1)")65D9F<65<=%E
@r1704
AATGCGAATAATAAAAAAGTAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATNTTCATCGTTCCTTAAGGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCNACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTT
+
7#<=(@-@4.#A"7;)!6C0?'"4?C'%24&,3?+:A234+'16G"G.'?</-CD.$*,:E2?"/"F"?=>+%<3,H%!=<!!*#5GA7:$@C93'CC'E*EG?5,F@)B/.%-0?>170-&<9C+8.#.H5>GFC;B%G?**.!)F/%29/=+3C:$,=3&B4'$.,3F.>(!G(;/.0=G#:0+/>&F>>@@!?76+.>,+<=>)E%(
@r1705
CGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGG
+
62H1&-%<?("D@<*'GDD<.#/3F:HB1#*A0BD<72E=DAC(&A383.B;F
@r1706
CAGACGTGAGCGTTCCGNACGAGATACATGGTAAGTCGCGGTCTCTTTCGCTGATGAAGGCGTTTACGGCTTG
+
@E=CD"&88"#-@587<":".5+3EB!&0C4%426:"<14AGE8$;F/D4E5H,6,'1A$1:D)%$$,,.E-:
@r1707
TCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGGTGAAAAGATGTTTCGTGAAGCCGTNGACGCTTATAAAAAATGGATATTAGTACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGANATTTTCACAGCTATTTCAGGAGTTCNGCCATGANCGCTTATTACA
+
63(21>;"+:++":F<1FF(H.F2<(E=/$5.+G8C851>F*;+$<+3G-7<<C?GFGE$C=*,")<%2?@12#'$;;)2A+$AH&,,,!+@;"5&!AHA)&>-4,!G!)A64.;+*9"#DH4..#C3"1'66%&7,8?(,41303DE?&(>>'G,*4@;?%2BA<;BB'C"BED+C(A%G060@58F'3A-B)H-C4+?G=DAF2G+E2C=EG1;A%"+6&61-8;5B(+!$=52E'C'&4(7,!.,4!'!$B?D$>+1')GH>?H
@r1708
AGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATANCTCTGAATCAATATCAACCTGGTGGTGAGNAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAG
+
,,1DEADA+D:9*(B%:'A;AA@?H<D&D8'E:72D1!"8'2H+!5A=D'AE<A49H10BD0*@=+*9)0&>.')H?5@F@!:"1'H@670"=2635#:$2,F"?-@@+C-4.3-&">@/*AB2:7;F5-/3G9:$:52&<9FD6;E!$223C-G@E)1C;%F"G6-1;-87EF,--E'4*&"B?9#.13>-7FDFE+=D@!.)8?@"GG,!CG4?A#=2*?*#E1:H>-H"8-.6//'#&E#4$&<63+,9BF@74D:)?:7&E#A"(11$6A/#8!05"HEC+*!0/C/3?)HG*%AD83=$!E3
@r1709
ACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAA
+
@G>-&C:#<,@0G*DF.H!:<H%#32+#D(+C+"G'7@??#:AB%/$;*>:%/(>(?%-9+%.,#?2$B8.+"B!9$-(,:1=,5)4%H6A=6F'
@r1710
TTNGGANTNCNNTAANAANNGNGCNANCNNNANTCAAGTTANTGTTNNGNNGNNNANACGNNTCAANNNNNNCATTNTAC
+
"!###$#$$##!!$#!""!!#""####!"""$!"$#!"#$#"!##$#!!"$"!$#"#$$$$!$$!#!#$"!!$#$"!$#!
@r1711
CNGGTNCTGNCANTGAGGAGACGAAAAAACGGACCNCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCA
+
)!$$*(%%'#()!'$%%+'#'+!&%%#())%')+)+'"($&"$"$&$(("!'+!''#+')+%$'!'$)$%+*$#%'*(")*&$(+&$*(!+#(")(%$*"$)('"#)++%%#*'()*!*+&&&*($*)$#%!$!!!$(!'"!"$!!
@r1712
TTTGGTTGATCGTGGTNCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTA
+
F)B--@*A3'*;A4(01/67%@$"#?2'H,@:<:>.)E$'F=@&B2H)<,):>#E;@'?G*1%CG?0G%1
@r1713
GCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTCCATCGTCAGCTCAGGA
+
?'?>(:21;2A6&)*3%!1=:#.,EG;=C),<8BC.%/9/3=5C@?(#.(H-E#)?7B537CCB1BF(=-7$@B'*E1AC;"'H'F?C883C/A%EG2
@r1714
ATTCCCCCCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCCCT
+
<E:=&#9;E;E).@,$5*139+E2=&);BH0B/.B+7')+H8G'-9:
@r1715
TTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGNTC
+
;@#995$5!'"<).%--%+9H'8'/)-1A56$AD=D"H5?:0/#$5>??B!B:#)=@%@C=;(6FG'G)7A)0H*'?#<:2EA6&*D"326;*<B0#(-43C,%4.)"D-:=
@r1716
GCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAAT
+
8<2;+EE5#$8H8H'8;,*ED3&#*5E20F<B"1B%-E*@D",(H!8
@r1717
CNGTATCTANNTTNGAANANNNNTAANCATTCCAATGGGTGACGATGTGATTTCGCC
+
%$$)*$"*"!%%$#*$#"'&!"!#&$")*$+*$+)%&(*+'$+#+*('+((!&%%#!
@r1718
AGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTNAGATGCGGCACACAGCGGAACTTATGAATNGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCNGTGGAC
+
=#17DD4G<6>H8'@7A)6:.)2<0G>@4#2+(?C&H1C>=5-@E+39)?=$=<F=&D$%4AG/B&>F#12>+8')<+H*$?H51:($*20.?.?:<9'@*>4/*+)=*:5E->)-G20&(>.1H'37?+;E4A=DC&F+H>>#/-0034?%E"H?49@*+79
@r1719
AAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCNATCCCTCAAAACAGGGGGACACAAAAGATACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCT
+
)-&:B#C'G>,%%"5&G5'7>H(H.25*(&,"9E/A2/-"8<%3@BBF<3@E:B2?6(5+:-=;#&0@H$'3%(3F"5=98H0B9./E%?E:/?0<?)H:<H?FBG/F;EH1;?!>C5(*C1/G=)1H8!4!@:1C((8(:0F882#5$3+$8-F6:4FB0>D@0,@:#<G36&6
@r1720
CATATCGCGCAGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCANTGTTAAGNCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTC
+
*&.H60G=-'B7$C;#)H5"E-=4F&<@!!@39>*=G(;B3D%/>!=E'(=9C>/)5!CH&',40F!1>G!7=)#DAAB-!4C/43"E+B?/B,99B>9(24=,?3D/+
@r1721
AGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCNGGCGATATTTTCACAGCTATTTCAGGAGTN
+
0F:<7E'@4(1<<=G37$&B#$@#D?G($B-@%<D42$)-;558/A;8A>1-+2+H5:@05-@FH#1@A9-<&65?:,);+
@r1722
CTGAATGAACNGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCT
+
G;723C9.8(#"!&$;/,>7;>592,(,A#6/HH=1"/6'9HC@%
@r1723
GAGACCTCCAGCCGTAAGCTGGTTGCNTGGGATGGCACCACCGACGGTGCT
+
EA-A,)G%G9'"05DEHE'@0?&AG:,G1FH"0;,1C)9)->036"%)$-2
@r1724
TNTCCNCCTCCACGCNGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACC
+
'"$''!&)+&*""+(!++&')(+!!$%(&$#%'(##*#)*&$"%!&'&($""$(!!#'#**")%*#!)%#%''%%*&%%'
@r1725
TGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATG
+
BG@/.9=1?/6*"2=.6B)=45%%;%04495;,!A+37*'1<#9)22),A83=<8%'2:'351F,1""$+73.(4
@r1726
GACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTATCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCAGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTANTGTTGCCA
+
7D9B;&*)=C!2&>":7H-5)5<!@.%##1/(C%F!@;)H057(C0G(@''+)?;0+*6$.:55CE68<6;99-)'F"<@=C,%0?*;(&HB,E,7F550H-B2'49"FH<?:!2486=:G&C#+;GCG:-@,92H,5G*G05C/F:D#)E+&B$F$@9<)3D(=<6!?</*18;":A-!%<D8204!,:?C,H%6>A.$B+7??0&7*4D6?88C7.H3.F)BEA@#A*B91F5>;'8'G"/,!>#""39-GD//?4=0-'<:&)".)=#4.&+H&+;.A(#?+-<23#;85'?@$F75.)*0HD0(8!51?G2;?&C70*(;,6D$G<@95?5:C6(HF3+/%/3H64A<6E4$7-7""85;4".='>BH.-#0<E50&89'1#"=H#.0;<0<.77='0B@
@r1727
GCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATNAGTTCACCACCTGTTCA
+
8(7+<-E%1;H5.;F14""H@'E'>>(+2=H4;4.:3)*E5H'?C5H9/3*5+0;&A0+0/H+9:&/
@r1728
CACGGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGA
+
A)H;%@+8.EAA!5@!7H.%E0">,:,(:"G5D"HG,$)CH5D$9EB.#6(,H1.1$E#%?2*+@'H-0#/C"7CE192C8?
@r1729
ATTANNCATNNANCCCTGTCTCCCCATCNCGCTTTCCACTCCAGNGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGNCTACANGCATCCTGCTGGTTGACTGGCCTATNACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGGCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGC
+
$!(""!('(#!#'&)&)+$"#($+)#*'("!"*#%($+)'!($#&!$'(!$()*%$)#!#+&##*+$('"+))%$'!!&"+)*+"*("#&%%#'($*!"&('!#%#%$!%%('#&++)&'!&(*+!"#('()#&!&&$'!*%%(*&)&*!$(#(*&&'"+**&+*$'#&')''&(#"("%)(&$#&($$&+*"!%"+)')(&$&*#))%&'*!"(+!#!)'$!)$$(#*#+'&&*+)$$+"%"&"$%)$#"(*)++'%')*'%%!'(('%%+(#')*&&#(%&&"'&&'!%)%#)!*&*
@r1730
NNTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCNGGTNCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATNTGCTGCNATCAATTTTGTCGTAATATCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTNTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGTCTCACTTCTGCTATTTCGCAGGTCCTTGAGTT
+
&+D/"($@$61@3C)D*C1<3'E#+>%,8GF$1$4**F6*6H>>=:?5@0)FC&H4F%#/>;-%*:(9!0%3,3'+GE-&3#*HD9##);4707%-HE1;00,=FD;;2D?+G9,0;'EB!2-"!<3#,>G.&C!,!*F?H<BB"41;-*F%%/?@2.<@'26:87G=$A?5)+*E/>5<'?72B'&0!GB9$=05@*8HA<@+34475&0"6?:+A19F(6&=<-'=6,98G?>++D.6!+677.3/!F)+6$512<)&;@*5%,'>@")&+D&A:A$5=.!H%?"DB+(2*(F>1H--@3'B70"5BDF(@H7(3B1?;D?@"HC&*2E?-G7G(-E+(1C0#!
@r1731
CACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGACGTAATTTTCTATCTNTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCA
+
-&'=7'G&7)H1"7D$#.2!:7--5G=?;:F(D&8=35!/F6A#;G5$*290F!2.<7%<.-330(*0!7'#G5.)G6D.:A<B..+-.+8,,-#/5.!.:,9/43H+1F,8#CE00!3!.3C=%E25>C+EF!CDE0E54G:#$8*'-"E5C?:<?07.%5'$DG!758(
@r1732
ACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGNGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGA
+
A+0>(3$.;4AF$HF,)68B)8(74<-*2/F%1CDD!F1A3<.26@.)A/<H4H$1-*>-)?0#6HAF=)HC-@E5*=2>9)>;!0$A1G?AC41371&FA17:;90C.%#.@%'!30?$;;/%EGC%7EC4'A'!C;A<3'>CBB+2EE.5@>-%
@r1733
NTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGT
+
!?CB.7*)*"#-/)72D>2))>%64?(!27,$@+?AH.5+/")991!2E&9"5#$/9
@r1734
CGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAAT
+
0B@"H%8&#@!6G:@".&>.39+/E6!H6AA5&"3E#A4G*C'C'4&&2!+:><FC1(H22.0&')HDF6-06?=--)G5##B<-<0!F,<B79%53D':,C,)2
@r1735
GTAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAACGAAAACGCACGTTTACCATGATGAATCGGGAAGG
+
("5G&2C-EB++13G?A!AC7"%5+;1B'H=HFD@G=96$8F01%BE4;;52#793;-,!%34&'1@0=G#>5=(7-,:'(<437@B1/
@r1736
NNCGGCGTGTTTGTNCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTNGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTT
+
'!).'+836CD14@#%%H#AFBG>4F=8;62-9&+*(8?7A*,<#1843:!/!4D./'$>0::)4A)(&:$(?,C+6B72D7"6A@0&EF)@6%9A58"$-7;%A"HC@,D-&:H-0/>CB7@6'
@r1737
GCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCC
+
3082;#D6-#8$8=-EH52:D:4-8:,4,??:F<(362&;6;&:F=C-)%$?+<6.C@7
@r1738
GNTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGATCAGCGATTTCTGCTCGCCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACC
+
72>@$4/=(07&!!5B1+>%F=2&<B74/!D;-&CEAD8)3%&D??C:A-$G;<;A/D66%6.@A*504'*-1B06;5(3,A8?1637D&9:6&.GE3C-/B>'>30@%E&&@:@!HE?@:/:H?.9B-8<A;0;>:8,??:#9
@r1739
CCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTNATTGATGGCCTCATCC
+
#3+=:)$G<-)>8D/=4>9A*C:.B1$-+B&G7><E0/5(0)75#%&+E9/)-<,;H'2GB/?:4<>G0H)?.E*04!-10H1F.1
@r1740
GTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCANCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAAC
+
556;;6C,,5)/;(0C,7=0)G1HGEH%FA"H*3%44)9>F:03?:5%;4B1@<BF00CE.D?EAC2HCC@%,<EH,<E1=D$.9?C,/E8<B/(/21*A+#87B0&%B%%'E$*2.3)CA>
@r1741
CGACNNATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTAC
+
((!'$')+%"*#'+(+"%)"'*+!"$*#("!#&(("+#&'"&!'()!!(*)%"")"""'&#&'
@r1742
NTTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAAT
+
$)/84@5<6$0:78F3)3@>/H!"(%=):(1%FC%EE=*!=,2?E0/+!/#D.
@r1743
TTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCATGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATNCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCNCTTCAATA
+
;)?8."EH59/@!<62,0*6HCC>?08&%D.B#,H7$3(:C943("%=G$7>9>@C<$!02,$0?E7,-#-C(>(!.3>0B7G;.=6B?>.D&D*G)H4FH+3G.7?,:=>&E,'C(.?:;,&?)!<'@+54!+.&HF-A7315"DF@A8<.15F(36DC:D75/&@B+C='@-',-<"A42:$:F/912@"+%9@<<$;4$4#
@r1744
TNNGGGAGACACTGNAGTCCCGGATGGACGCAACNCGCCAGATGTCTGCGCAGAAGGTGTCGGCATA
+
*!"+!+$&$$%+&!&+'%*'()$&*&!'*)%**%('#!)+#++*+*'#*'("%$'%(()+!+%%$%$
@r1745
CTNAANAATTCGTANNNGGNTTCGGTNATTCATNGTGNNNANNNTNGTCANNNNNTGCTGTGNCAGGGCGCNGNNNTGNNNNNTANTNTTCGNN
+
#$#$#!!#$$#!$!$#"#!"!$$$##!#$#"#"#$!##$#$"!"#"""!#!#"#"""!""#"#"#$""##""$$!#!#!"#!$#"!"!!#$##!
@r1746
CNGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGNGAATCAGGATGAAGCCGGGCGTTACANCATGGATGTGGAGTACCGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGG
+
"!&;34GBCG0$HH:EF;'"0=.8E8&(F>8;3FB6=A#F,>88"B*B71;91C0C6%!1&F!GB;(<(>,(G5:8?5"8@(7//7$E??'$>+!91*9%37*5>(F);&G,E(?2:&?<73G?C#$4'<&6;C59*@39D+:(>8D*G+9;/$<F5"A,%'1)2(3E608!
@r1747
CCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATA
+
$0.28&%)B$0=D6/?63+%.?541"!9;=+:9D5-6:G"B(D8$*@D0)"<(E%@:#D&968517>#C&3*.D67=;=::>@')/&.
@r1748
GCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGC
+
AC=/-2A@B;;(81<,'"CAG18/B@885B<0/?.07?E<H@>-B:"EG:>
@r1749
GCCATATAACAACTAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGNGGTAAGGAGATCAAGACTTACGGCTGACGAATACCNGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAG
+
0#0G@:&6.1?E*06(?#(98F$374(!-->>FEA.6?>.+BD(*7F3!70$9$G2>**H)6+-2G%7E!"B6,6*'H$+E2(!:%&5C"-7'>A@FCF(H5-/A-3E@>5,B9*.=&ACG/>.+#,
@r1750
CGGANCAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTANGTTATCGTAAGCATTTGCTATCTCCGTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCANCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCA
+
=@2)C(@76'/*""@6>"F$9H1;EF-=6:FH111(@F%)4(.*1:#@2B;DB373<#%?"%37%E6B>"*#"(G8(&."-E1?+<""3#>E.2<BBG4/7/4(E0E)9?6%<A37*B>B6,C#8F"?F$.?&CD/9GH*!6/=:C)GFE(7;.@C:)8D7EG()*6#@7G3A),D;%#,*8D-#0::;GEA,?EF!;;@!,;DD)<95D#=0H<71'G*?2:734-4?!'!+'8#24-1,=
@r1751
TTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCT
+
H138H1C><?#9>7"5E*.E<!#-(>"/6=<8)&0"<070=:31?,/>*B=,C/@!+!#3>@+2G5B-:D>
@r1752
GGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATC
+
83&(C513B#043<8/-74/.4B8@&*&*+6.,A*./C:G)F!1F.7$CB?A=B0>,=5@;'EA0$C5GF@&:A*3<2?)%*AF<G,
@r1753
ACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAAAACGCTGCAATCCCTCCTCATCTTTGC
+
3**C><F3!C@;5"D.>?D"/388@'B-.,0A56(164+90/C"%-(0!.C.+1,<7&C<:/!F;<9/;7B$<>#?,-%)G3;DE+A>0+B+)//649"E9!>$DD1&:19
@r1754
TACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATCCGCT
+
G.=,+#B7:>68*@9'C&G;!>F>&%,4,!%5@&2%=5A@,9/>15,?(F%".457=,7BCD&!+2$+<2HD(+":HAG
@r1755
ACCAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACNGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGAC
+
(#'%+%"$"%)('*"$*'!)$""""#!)%'!%%+#&$($$)&"(!$"'(#*''%"!'!+'%&!$&(""%)!$$"%+)*""$((!!("'#%!
@r1756
CTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTCCTCA
+
&3)GF8:4B>>@F1)6./7@/##H3(%41/56.<,1'8#C')1@5#=-.!28
@r1757
NATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATATTCTACTCCGGCTTTT
+
$8?BC045,!E("?:;@CC8="*%)3G2<&.5!@D2F%=8"&/95.)G2=7@#5'.7
@r1758
NCNNAATCTGGATCATTCCCNAGCGCTGCGGCGAGTTCATTCANCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGT
+
!)#")!)#&+)+"$$"!$*)!#""!"%'$!$&**##$!%$&!&('#$)$"*)%'$%+')(##"'(%"&$#%)"*$)&&+&#*"%!*")*'%&
@r1759
ACCNTAACAGCGGACGANGGCAGTGAGCGGGTGGTCGGCACGGCCCGGACGACGGAAACCACATACCGCTTCACG
+
$&'%(+#+'&$#)&"&"!&#++&&)++&*#$$!*++)'+)"'!#(#$$$*"(&)&&!#$*#$$$(&%$('$$**'
@r1760
GTTACGGTCAGACGGAGCAGGAAACCCACGCCCTTCACCACC
+
++<".<59>,)$0@;1?A4@D3-&-$.H23@#65.2>,9G0G
@r1761
GTACTTCAGCCCGGAAAAGTGCATANCCAGCAGAACATNATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACA
+
$$%*+)$(*'%*!""&!+(&')*)*)*$")"***$"*!'*(+&(&#*%"(&#'!+$"''#%)#*+#&(&!('$'$%!!*++#"("#$)!)'#%'$
@r1762
NAGGNNNANCNACNGNCCNNNGNNNTGNNCNNGANNTANGANNCCCGNCNCTGCTGCNNNTCCNNATATNNNNNNCGNTNNTGTCCNAAACATNNNCNANCTGACNNTNTNGAANTNNGN
+
!"$""$#"##!#$!###!"$"###!!!$"#"##$#""!$!#!#!##"###!$$$###!!!#$$"!!!!"!"!#$"#!#$#$#"#$$"!$!$#"!""""!#$####!!$!$#!##!$!!$!
@r1763
ATCAGCCAGAAAACCGAATTTTGNTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTG
+
F!HA7B171-B9:H3,&12.A<)&<97C7DDG'7?GA66E*3%E$2-;+E-H0-/9'*+<;.+<50+6"':*6*2<#/)+>&FGB"H2&3,
@r1764
TGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGAGGGTGAGCTGNG
+
!%)+!!!+")%+#&%))&(&('"!$#*""(&""*!%#**&!%)""'")'"%("!"$&%+"*!#(*$$!!"!!+")*"!+#$%((*&&!'##"
@r1765
NTCAGGAAATNTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCNCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCC
+
&,*"7-9<@8HG"%EH9*.0B<>C$4*H!7D';-4:#%+F19''">."@".=FC;)7785H&(85+F15>!387,2.A;@D,AH7588:5:';E(EF$:D0@B>:>++C1&,B=F<E:(G12CG2*,:=-/?HA6C@(+9*>GHEC,H35GA>#9@0E)(9B
@r1766
CCGAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAACGTTATTGA
+
%#&+)&'+!%%!"!'#%)+$'+"%$""(%$+%*)&#$#$##""$)$'*(#&%+$&)##'
@r1767
AGGATTGAGCTGACGCCGGGCTATTTCAGATAACNGCCACGCCGCATCTTGCCGTTTATG
+
F#=G4;FE!+A(=(@%B*2,"/F5.)=9;'HB).:6+%A>5$>F,FG070$C!F?5E@!4
@r1768
GATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGC
+
!499B)3.#EFB=*:GA?1H"7B8,#A=D=+!(#B-!D:&&(E$)B%<#703$GAGB374/FF)AEB,H,H%G@<E;!7G<..G)&BC<@#??,*)GB:)>!94-3(C0F:2CD>-(EC;!$7;)7-3#-E,37EE#$,((7*9B%E0)D)!C<""<8)A*:FA?GB.=D617&CA5")1A-G#%)FD>*8B>+C=05
@r1769
NGTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCTACCTGC
+
"!ED>G=/C"6#CC(?-2;.'!<F4;8/9"@-;@,2.H+'4DA9'/5A7B$+5G17G8':=6A(1!9(59+GF1049=-!<4;.%
@r1770
TGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGG
+
?.70=-;(3,!-;="6>'%'05GE-%$B++D2"1/8)5/.&<B6,=A
@r1771
CCTTATCGACATACTTAATCAGCNAGGAGTCCCAAAGAATGGATCAAACACTTATGNCTATCCAGACTAAATTCACTATCG
+
+&)(!#)*"'#"%$$(*$'(#*)##+*()'))&'*)'*'*"%"$+*$)*!!!!&'$!*"&##)(&(($)#'&+++&#&&'&
@r1772
GGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACG
+
9@;6'H.',G/"/8$=>:E@0483!%E")4D:C(A<@:"E=*9@%$=;;G15AG0,>"G3B66'>*:<+<3)5G3@0D=7(9#!-<E,4:>;;D!@;<"9B=C9+$"&A9#-$*>*!$@96A
@r1773
ATCTGAACTNGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGT
+
+.F<2,?6-68A8H(*1G&9EA'5G(C:89?&.#C5('410E/G$G=012A2#F;H#
@r1774
CACACCGCTTTTGTAGTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGNATGAACTGGCCGCAGGGCTCGGGAAT
+
!)+((##"%)+*"!*)!(+$'!*%#!")'$'('#*(#&"%!#*''+%)+)$(#(&*)!#*#!)'&"$"*!''(!'!"#+'%%##(")&'+"*
@r1775
GACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGC
+
+)*!$'&*++%"'##&#+!)"((*+$")$)'(*$('%!$($+*!%'$$*$(+"'#%("''
@r1776
CCGCTTCACGCAGTGCCCGAGAGTTNATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACNAGGCGTCTTCGTTCATCTATCGGATNGC
+
6"1%@/2/=BH@:.+=CB3;<$"B50@)8)%/C=D$*.2B'E#.+6C=D,=))=?+E1+(=-2)+5-,9-"&FEC"66A"77*/>E,6.G@+H,<F;!:'GB4!D-"%F'&51)(CHA':4&>>621E$!B5;*08.D"3
@r1777
TCGTTTGGAGGCAGGGAANCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTT
+
2=*;%18=(-@,60/,'2,*#D;D1B,15(-C@+,CG8)79>$B@D'#-H+2E&<:E!078@8*#<5(-!;*H97"!'(CC5H06DH$"B<D<2#?!7-),#'+@#+4&:@H4))<F,B>HE7%(A;&C,>(@740E'.3:&&D%/-@5!%>48G=;H:/=<8/FGF=%B71F@!"89B+<+,D1$CH0?0@EF"#D,G$-87;B>:#:D$
@r1778
TCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTTTCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGNGGCCATCCTTCCTGNCCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGGATGTTGCGCCAGCATGATTAATACAGCATT
+
7=G9><(@-6CC>D0(1$?4>200=-@=71FCD@5,-D(6(!7@?F%9$$/0>@"B#E93G(%.1D<G$7D.$=/&"#%D%2450<42=6-?9$;2A(:A7??).CGGA.<=;DG?'7,?E$(3?%)E)D-(#!?(#),!D6=0(;(1&F6*5&+AE/<&25H/F&;1?:.#7>2)1%(-,%!H.CG0<61%,:=H.+FDAE/+H/D+D0G$/:4=3C<,$B$6H#&5+9C.;1+3H-;B:-038<)>7B
@r1779
AACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAA
+
0*:@&19B@"526=%3-E@!BH;(*5%9;B7'(&(7;)+?;=.$/;9
@r1780
TNGCCNCCNNTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCTGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCC
+
**(#*'###!*$+()&"('*!"#)%$'')(%&'"'+(+)%"&+&+*'"&+&"*%(+%"%)$##''(&$''*((*)#$!+&*"&$)$%"!(##'#!')+'$*+)'**!*%*("*#'$)*)&&%$&&'(*+'!&*###(!+!""%%$!"!!(""#()#('$&#')+##&)+%!+'%(%"%'#$#!)("((
@r1781
TCACCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCC
+
840.&DH=3@84@!!G0+"(G<(<"BE2()A1:"E(C!%<3&>FHD8;!G:B5
@r1782
TCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATNCAGGGTGAAACCATTCCCGGCATTC
+
-@+28+.=%DDD-%(.,@<#B'8*.:)9$A%!(-%AH"-+1?"H;&8(+#/)A$.92144)90BE*3C:7?+9<D+-:*,31#8GE65C$>EB4%4-?F)3H2@%;HGEG
@r1783
ATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTT
+
248D)H?/G7/D(C<<7&6>2/*%@'E9&'@A6G&+H>%A
@r1784
TTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATNGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCTCGGTAATGATTAACAGC
+
%4:F//)5>/C2!C$-&-H8()*>7A:*=+C"25=0(5?F)2A(17%?H1&D.0$+4!##!*A&/),&D0./6?9-6.95E:=&7;.'D*B4;")&C@),#E!;2D05$?GF>5ED!:A3));16/5AC>?%)#%=?36H060+G3-(#,=<>:=/;$>0:)!F6
@r1785
ATATTCTATATTGTTGTTCTTTCTGCAAANAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCANCATACCTTCCGAGCATTTATTAAGCATTTCGCTATANGTTCTCGCTGGAA
+
,$9))-A4(*%!=GFADE9(4@7FH&0A<2)5'>/>=24/"25#0-'&!G6%A&:,,H2$"*<11(E>4H1)>F5A.?2@C,<'B8-@!8'0A(0<-1B=8BB%$,&9?7BH-3?=8/.C*2G(6F
@r1786
CNTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCC
+
)#&+%!$*(#&)&'*&%$&%$*#")+(+#)''"&($&+#&('
@r1787
CCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAGTTTTGCTGGGTGGGCTAACG
+
C*B+4<B(,%-#>+$(&B6=F(=4>>EDG%8/1263#-&@<@7!<8#%*.!AF,H%A:C6C@%,H#G%D.7=>169/1F6A
@r1788
CGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTNATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCNGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGA
+
.9,5#)79;#(,E8GA1FA;C"!&B1,@'5!/#5E91%=?6#/F)#BH9(+;25>=;>--5E1#07-,?1(AD3.:=9C4""FF4"&1*8$>":A29E/FG942#$&E3F%0)&&B%"14?@'2/'56;)<!0G
@r1789
ACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCACCAACATGCCGGA
+
080-'A63B.DF"?#!;1562D!D(4(802B<+);A(1()2,0=F)E?B"(C#!#A3"D#;&1!2.),@+*7,,1%(439&;F)&F.6F(/?$91D*&(<"0H,$>DB.18
@r1790
NCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCNTTACCTCCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTG
+
%707-<BB63&88D$$@1C6AB*8;'<?D7%&3E/>!;$:4F5;8+BC@4?!:A>72F<1D?F#&FC/27B+"C/GHA'DD6!>:1ED<@?</B29,B-1B!'(
@r1791
GCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAANATCCTGCTGCTTTAATGCTGCGGTAAACANACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTC
+
;8@(F31:6'&3(H"C':7/6BB.04("7F#8!)!:7)G#"+<+=*"*4F&+H3.%E@FB,A06+-@,:B:!2')-E3-<A@-"0E40@51250F4><'!*H46GA'6/'&"H$D-4&E:%<<8>&.%%B0?#
@r1792
CNCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTNTGCGGTCAGGTGCTTCTCCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGGCGTCAAAGTGCGCNCCGTTATCCACGATGGCCTCTTTTTCCGGC
+
))A.6G"4=-6@:D*0B<,1F<E0)<DHD?<<?F'%G>.81&?$<4;@:%5A;'A627:3::?/@0DA3G-7&<7#$DA8B;/AD7.53&$@*(=580C7=;+/,%.'05&,7%%C4=8)A63"-1(3@ED#0$E#,@/"GC.+
@r1793
TAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTG
+
/)31+G)$2!E6?2):/DG(!7F66EF26;5*+=$+#6#$(3*?)/
@r1794
TTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACC
+
H-1$'-8<HF<&1-0E>)"GB=#E//=-G.F(/9<BD7B<9"A&&-,9!<AE2)?!>HH(-"#:F83;)/*A1/:FC9;7<;@9(E$4%#:
@r1795
CCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTT
+
7CAA145=A"<+97D,+13>!!(6BA7B"74#>6:3<ED,C/2,70@4A9///5,1&-9
@r1796
GTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACNGAACGATATCTGATGGCCACGGGATCGGCGCACNTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCC
+
C/2=A@5;4@A@-*8,A'./)CAC7C71+A2H,AG.)&.6G-6!"9E6.G?'?C09GH3#G5!><32>>6G6#C&85!0GF;.'!;1>,&%')1H3>-656,:F68/6$CD*@G+-(1A'!>'6!&.=**.B8-&;.<<"=B619GB;
@r1797
TGTATTCAGAAAATGATTATCANGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTT
+
(>C%HH;@5(%,HA:3.A)+!!9A6F(C2(!G9C!16A'6')1#9D-E"F?/1"4&HC?*.8?A<105*"6/
@r1798
CATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGA
+
H&5-4+)300@A>!3AG0).#16#'?96'EEF*F/@>3&/6A9'0"(3D3D+E+%05H=;<+*7+19A"'1G(GB#+/H++'.A7H-&2<D=0-1)=D?*A-+C*.A<:@--%'G(5%6/G<4D"01B<D1?15@EF)=>'()B41H:AH"AG&>0B8;
@r1799
AGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATAC
+
C(>5->0(37'B=.5=H?1?3B#4,H(67GGE"+A36F7/9HHF?G$@(@85)=;&7
@r1800
CAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCCACTTAGTATA
+
+3!)+%E12<-+2>+9+;@616'D<"=(,&B?@7E->G2==>9298""*++81B93D-)8A/%!-.F!/.1':7A&?97&'#:/7D!?
@r1801
GCGGGAAAGGCTGACCGGCTGGATTGGNGAAATTGCCGCGT
+
?CG*/;>-+1F7C+C'B''H*10B1=(20$6%##>*%>80<
@r1802
TCGACCCANAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGC
+
+%&'+%!&*+!'##')')*&)(&%'#)+%'"!!)(!'!#'#)%*)'')*%%%%'+#))'$%#*"&"
@r1803
GGTGCGGGTGATCGGCGTGTCATATTTCNCTTCCGTACCC
+
6?BC(<9C,98C6G>6><)BD6@H%BH0:;)E?(C/GH"<
@r1804
TTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGC
+
'9"(#=G,:<CD??#C"B2A0H;"B>EB,096-&:@04@@=#AD>?@.-5'C?14,;5>B)%"#3##2;B4HDH798>.<?.'&*A%"075;<#(B7%A)9,<-<3DC'-
@r1805
CCTGCTTGCTGAGGTTNGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGG
+
>'#(B(CD%CD6(#?6+&?5B1"51B9-9@+@$H-=?:)4H/??G4D)C(E-?27+%/E2"
@r1806
ATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATT
+
;(7=#*C36(/-G("F@(F=>$#-&:BD%&*/A!">$H+)'%3<$*3
@r1807
GCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAA
+
.(=E%E8%+CE:;<43,/F#A0B094C8?8?=%H?#;!24H5-4&"@2E-?+569DB$(8*%'#1&)GA05(/*=)C4?$56;':@-:(+F$=FA=A:>50/.-'FB?8%)%*":34B.F??$A?A+;&)9C(G@?'<3=?A35"'4%/55=+'0E?HB@A@>*-75<!>%7F;'@&8&9)2(&CE7:%F+BB83-1-?C*0=6H>
@r1808
GAAAGGTGCGCTTTGGTGATGGCTANTCTCAGCGAGCGCCTGCCGAGCTGAATGCCAACCTGAAANCGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATC
+
,G?3%!G7G,&$3<?<H0(&0:192@$&(B5(3G"3!D;BA=8<348E+*E).1&B1%)C<+-2F)3?:"#E:+E4A%A)*?$6*:1F*3..(9(-"91&87*#3@3;/"%F*'."317GHH8#B2:F.)6E!.&:A"=6,$3E4H@"
@r1809
AGAGNTATCTNTNNGNTNANGCGTGCAGNNAGTGNAANNACGCATTTTATGCGTTTT
+
"))(##)#&&#''%)#(($)&$'&($$)!(&%&!%%!"!"+%+'("%&+&&)#!!#&
@r1810
AGNNTCTGCNNCCGCNGCCTATGNNNTGNCCCNNCCNTNANNCCCTNTGNNCNTTNNGANANCNANAGCGCGCTNTNGAANNNGTNGTNACCANGTNGAGAACNNTGNCCTCCTCN
+
"#!!!!#"#!!##$!!##"!###!""#!"##!"$#"!""$$!"!"#!!$#!$!$""$#"$#"$!$!#$$!#$$"#"###$#!$#!!$#!#!#!!$##!$!#"#!$"##"!"$"$"$
@r1811
TAATACCATCTAAGTAGTTGATTCATAGTGACTGNATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTNATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTTTAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCAGTATTTGATTTCAATTTTGTCCCACTCCCTGCCT
+
;+6;9=C5;CGA;"!8.40&+G"8@(>:)A<8DD"57596AE!&%@%:G(H&0%H-/F=<95""3.3=@6"H!=!H891@!A.-@EE>5G7!:.3397)8+!$*E/1''AF;*AE'!>?01:,3H0:9-G;*2<9831)2!?.G>H7!2/0GC*<?5B;35?+7-.EB30@*)8>8&"9FA375,+&%+69!8*!%B#H84E+.6+>+6*B<%9#9.6'!2"A?@@B1"/"*H'C!0'-$0(025?-:HE
@r1812
AAAGCCGGCGAGCGCGGCTTTTCCCCGCCAGCGTGAAAGCAGTGTGGAC
+
D5<H3-6A=.F'%-C0"-.'F.;8(%H7C@6DA'"52CE#<F*H6)HC3
@r1813
AACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGA
+
C8B8.",AF$#=/=8-"@//4-G'1,#%45<*@%3!%A0)(81<%D3'B2@9D%#/>E)$';C0,)65:3,H5%A@D1B#G71:%#1%"F?#!(>1'7E)/D$4:.E/41'#B;H&
@r1814
GCGNANCACANCGTNGTTTGATTACGGGACGAAAACAACAGGCATTNTCGATTACGGCACCAAATCGACGAATAACACNGGGGCTCCTGCTCACAGTCTGAGCGCTTCAACANGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAANGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAA
+
'"!!'!(#&(!$"&#%)+&)(&)#'!%''%$"!%"!)#("(#"$'')%"'()('$''&%+%$&%)$'*%*+&#'*)#)**(*)''"%&+&$*%)'$(""+&##$""**"%#$#)'%*(#&!$%(*')&"%&""%*"#$$$*)'+"%'+)"("#%"(#(&("("$&%%%((#!*&$$%'$!)%&"+&&**$!)$++*(&*#("&++'!"%!$)&#&"
@r1815
CATGCCANTNAAAAGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTT
+
*")#"(&")''$*+*'*&+#"#"%%#$*!)##''&$$"$'*!%!#$''***"
@r1816
ACCNGNACNACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTT
+
!!)"#%&#&+#"#&&"+##&(#&+&)!(*'+##$*&$((&#'%$&!%&
@r1817
CGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCA
+
E.F/$.H:?E3%25,A'>0'G'-3528=0#96,(539%6%
@r1818
TGNNTANANCNTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCG
+
(&!#%)''$)!*(+$"'(&)&!()!!*'%+!!"$(!(#%+#$!*+(&!++"$+&)&$)#"$#)"+)(*)$$!$!"!%""'+*!#''#(!!"$!!$!"!'&!&(#&*%)"$'")"('#'*((+)!%"&$$&))&"(*'+)&+$'*%''#%$%)!$$+%(+##!)
@r1819
CGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGC
+
$F=17<5B5$3!H9D!4+*/.4$&-?+49%!70D8(,46%,;
@r1820
AACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGA
+
<>9H&H;*G*01*#E@,E#0-%3*B$$(4-".4(6@E&25*
@r1821
AGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTC
+
A7*@&:-%!G>5)=+@F:0G,53?G%)=#DD:<4A2B(?2>A8*G?H?;CE%<,95B1C&;@8&2;>*8/$..=E,0<)
@r1822
GACCGTCTGCGCTTTACCTTCGGTGTACANGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCNAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGNTGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGG
+
3?,<%4-*B:<(<A')8GB<7"((*<7'(/;8):#D>D$&?A$(<'/.H*':<+6/6-6(7'##*E170-.65?)0*($80:,G:H(D7!H;?-EB$4H3:%:%(CA58DC6F4?+E7C+1CA%"D:AD"=$$G%D3(H?3=.B4H$7)$!2CE*</-71?0'"A17);&5A=)*
@r1823
GCCAGCGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACACTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTNCCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCANTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGA
+
C0&@8049/:#((25G*GB16!5@::.4B:5-2$H6.9%?4E6)FB->H9.!H-=;*<+D8&&5$<@5//=9$!-=E.CC?B)#.1!FH!@,"35&>C9$7EBF(8E!FD7D$+&=(';&D<#$*0CB0;C(D@;'.(F58:DD.)"H97%/#;;H00E;'D(3,.;G#;E*=CA%0:<%.F33:59+B!E8%/"6.5)80;%8>3+"$$3>AC&9(?H1:0<(C2539-).#3:1"BG&@70C1>DD
@r1824
GTAGATGAGGTANACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATG
+
0:7&A.5BH:&.;47'@D%:?HEB*E35E?AA0"<,A@&./"7:H/C=,>&2F=@D#$8>(3H$'4C?94H:)2G/-A=4$.D5=021*=0#;+.;EE2.<-8,,H7*B-=8C-?
@r1825
CGNCCTAGGACTCAGCGGTNAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAG
+
&'%'!%+%!&+*+*!!"%%%**$"*%%'%*"!)#)&")#$&*&"*('!&$*""&%"*%&"$+(+!&(+)+&*()'""$$$+*%)#*$!'"'+$%#*)**"+"(*'(%$("%$""!*("*!*##$$&"$)*"%$+#!*'&*!+%'#')*&&$+
@r1826
CCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGAT
+
;H9=1#H!CB1#4:(F*@%(5GC9:2*,A&!;&F/8";)B#"75+7>$!B%8)H%$CA3,$:;/D(=/B-B902"@<D#932F7;:BB
@r1827
ACTATAATTTTAATACATAATGAATGATAATAATAATATTAAATATTTCCTGTGTAACTANTTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAG
+
&)))+%#()&+('''"!)++*')+"")!+($*'!'+)$'$!$#+&%)$$+!#$+*)!&$(*!$'"%!*#)$'#"'%'(%&"!"""*))*))#!%&##!&%+)'+&!*$"%%")$"#'#"%(')$+#+*+&$#
@r1828
GCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTNCTGCAC
+
00G.9,#,?6>-?ECE?B7)H&5)A7C?E=<$%;G>%-G<&!5H82))+13%7.?DF!<4!"@9-G)+A1)A$2D(7)DE?!C;GG
@r1829
GGNGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCC
+
#$!+#*'')!#('((!%('&")*)#+*#!!+%&!'$$+&)'*%)$+$#!"*"!(!&(!)'%%+&(%+#"'#+%**((##)++)$*#&#'
@r1830
TGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAGATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAATATAACGGTGT
+
+H3&D304='+:!1C'>AB!D:$>DG@EHGB1+,:=E1;B>E99G3+6?:!!'1C&58(6>:<-!C#8=GG;'F@=.C%G<A@!?H7=4.E>-#*&AD$?60G.#HA;G:>@&:*A);4/'4.4"B!<6B-9??:D-0"$E)%C1:D%%.E;#BE/@+,0
@r1831
CNNCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGACTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCCATAACGACCGGATGCTGATGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTG
+
%"#+''+("(((!)'&)$%+()')%$)'**&'%%")###)")*#&")$++)#"'*+(%$"$%&&("&+$)(%$+$&''$"!"###!+#&&$%+$!%$"!**+$+*'*'%%%)+'!(#%+%)+'(%$)*")*'")+(#(#!!("!'&"**)*"&&&(#")***)(#+(!)!!('+(()'&#!&##+!')'"+%*$(('$*+$)'#*'%%%&!('*&'')"!'##""!&(%')(#""!$%'$)%#"
@r1832
CATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGNTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGAGTTGTAGAACGT
+
<@-H>8=EB2'C%4+H;&!<%#:*F36+!DB=&B'CD6D6-!2F#FG0#?3-=30@:/HD;3.E=#'/+52)4';!/-F(:-#&?'-/'9(D>,H9<B,,'#E','&@+.71$G@#>@2.?7?<B92&2%-5#D<@,""5?<),"+*"<81F9.159?%&-4C4!'@-1G(<3)BD')
@r1833
NCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTNATAGATACCAGCAAANCCGAAGGCCA
+
!+"!!!)%&+#&%("!%+$$&"+'##&"*($!%##**!+)+*&'%)"$%##"')(&!#!&*"!*"+""+&!)!%+'
@r1834
CCTGTCTCCCNATCTCGCTTTCCACTCCAGCGCCAGTCTCGCTTCGTCTGACCACTTAACGNCACGCTCTGTACCGAATGCCNGTATAAGCTCTAATAGCACCGCAAATTCGCCTACACGCGTCCTGCTGGTTGACTGGCCTATTACCACAAAGCCCTTCCCGGC
+
:*!H@%>:>D.820>0("('74*=+#/:(B-*H49D!DC$-,9<>=A#%*$%5.2)=<7.1.G,(B-!>+"4:D+/*''>:70.5/G9#2D.@&."7A"4&:F*."3B,C!*1-#A'5<?;<.E>/#1&$18<B:@/F9G=>#)2";6492;A0D,E?<@287<@
@r1835
NNGGNTGNTACTGNCNGCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTANAGAAAAAATAACGT
+
"#)#!(*#()&&#)($+&*!&%%*%%(*+(!*)%#)'*"$&$#'+%)&)''&#+(#$#'#&(#&#'#*&')')"
@r1836
TCTCCAGCACATCAGCAAAACGCTATTCACGNAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGT
+
9$;.0&-<%))<+<C;5+C+7#AF9"D7#5!43B4&4.#>441+4@(4,6750<":C*D:H-;0?A2/F$&>;1&H/)'HF@A%-+D4=#?A?8.H4F8"<EF$50;/F3.G?A=H<=1HH4(9;4H'@,("@G*)A5G;A,@D&-:?0;%(5:&#-27.@E"4C'G9(!H(@)+8"<F*3?@21>6;$"7B#8
@r1837
GAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTAAGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTG
+
*>D62A8G(!F$<>=>*-7%5(9HCD.30<.DE!>>)E+;4C-B9.5@EFA>%#!(3%>/7G;/EGD44A"5!A!+C='>'(F:()G+@%'C!)E=F$(-7"<:4!%G"67"**##9;=<;-A9"?-;:=FH!&3-HA6:&<=5=D?8E.(*B9'#,!:6*'F:>*H-?+H#
@r1838
ATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGNGTGAATGCGAATAATA
+
5B0>=9)B"-.8#92;.."%4"C!)8)GD388(@5<8?&D,<H7@28D:%"6"%?20C"8=;64F%<
@r1839
AAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACCAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGACGAATCCTCTGA
+
7(2#D@E)9+3:BD#2'"&:A69E3>!/'<!8.AG@6AB3;6.16"="*8/:EG=35+331&<7-)F=:9(!<.E>7$<D7$7.%A'6?@$BHH85#?5.'F28,565+%+%02:G13
@r1840
NCGGGCGGTAAATGCGNGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGCTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGA
+
%75<A7@1;.8(4BG6,24#C,(09@#@%/AC!*'$372"D)23!=)'8(G7&'21"%"<;")'8C2,61&&EA!-*;,CE9.-01,>$,(1G=BG!@=;63C(3!AB=:G)-"1:F=&?D*(1BG?.9+15<+-?"34E,<":C!H'&-,-4C!!-#025-$B!44<.@#0C9,;:G<3E@
@r1841
CTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTNAAAATATCGTCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATANGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATA
+
D=C);A+/&4E";CE3#':<?B.7*/8"0."(@-7()$.6(77#-"02'83"!4!7E<B#:-6$&;E#7,39/4$.D@81)DC5-4B%%$>"3+GAAD<&436'GF:B4%>3',7&D"4E,G.<035#1"G5G)+4#+G",=''0D3*H*-?$H*0%!54.A=B8#$/#4D0":-81,A1)D-"BAA2?F./?(86)@8?B!;-;@,
@r1842
TNNCCTTTTACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTCTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCNTAAACACCACGCTCGATGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAG
+
'!$%))+%%$!"$+#(!("")'#'()'+!(#"'!!$$""*!('*&&%$"*'*)%(#+")()"!#(*%!"$#)*+#"'#'*+(('!'#!&!(&!&'*)'*!*+"'!"$$&$#*#*%&+'"&+)")()'*$%)+"")*"(*(")"))%#!'$&"()$"**"!)(+'&
@r1843
GGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGNCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTA
+
94$C8.C(*B#+@0<7>$.CA3&5C&4F*@,":*3/E"46DB8:>#*7'+!F6;(%%#&,!@9G9$FE09*A:/2%;<:%G'8B>21/$>'D?7.&6
@r1844
NAGGGGAACCGCCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTATCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGG
+
),:@:"-/0:.)+A!@5-5362)"B)"%B)=4)##./E($;="H62C,HB$-@G,7A0F%F$<GH199E#;'28F79D-1#<<.D*C*4&+AG?.F3DE*6C9&)$,GA'*"AF+0E"F-&<+5FC4%FEGB.3E/-3@!:$@@66!CC18$$F3H3,8<=/4):$''("@(./.6&!*01#+D:*=A@/;*&(*"'
@r1845
GTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCG
+
:C'@&&$!(6$9):G18@=/'$*$906'1@842,375@4A'5:D
@r1846
GTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACT
+
91?$B342)+5!F(A9"?E8B4!)$"&@;96=%3!HG&)-$616"991(218#+.CF5D=)62D2ADA;
@r1847
TTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAAT
+
/*?92&A$=748D"(9#?1(;H(/5@=*B6@"6%C&=;:4G=1;?<'A7/A)
@r1848
ATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGA
+
;,4'8A"!3/@"7!3@>)5HBCG"G7/42F9&-#HGF',&.A<)43(0/-:3%2=/&#6;=%!/G/H2"")/+@3A0>;5+%4D=H:;4@)G/1:@D9/;HF+D-&"3/6,E3H?$%%*')%(!0.''D
@r1849
GGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTNGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCAT
+
"9#8G(4C)9;98>G-E40:EB0.BA27"9982,8A1F>';?2-,.$620=C$808@H-6=?)2::/)=F<??=8F8$51G"21G7C5&"2=AH%?'"
@r1850
GCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATAGTCGCACCGNAAATGTCAGCCAGCNGCNTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCT
+
@F!2C;HE7D%+B@8638")+/:?B-119@5@#@=E0$4F(H1.9.H3@*:7!+3.#G.'B(GCG0@@"$:"9=A.!%,G:D:9,?)2H5;!C&F0%?C4%H3!H)!"#'6!=B"/-*A@#+/>4#H>928G.:$HG(08+='H4(579F
@r1851
TCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAGAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTA
+
"@-G20-"9,F?HA"HB9:'#.#(%E0+63#*;!F=2.2C@E9?6<7>;:*4C/=&E$%>5%#+;!-$6@;'7>F1+
@r1852
ACATGCAGTGGACGCCAGAANATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCA
+
;B-):?%(E@=C+423(F>B'D+.%5(@8B-G7G1:B4)?<$#:>?:.@-9+337A1&@-=E(%@C?719)1(75:E8??1
@r1853
GTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTC
+
)+#*$)+*"%&$)+)'+%!(!*$"#&(##)(()#"*%'%*%#'$""$!)&!*%&$
@r1854
AGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAANAGCGGACGACGGCAGTTAGCGGCTGGTCAACACGGCCCGGACGACGGAAACCACATACCGCTTCANGCAACTGGCGCTGGNGAACTACAGGCTGACAGTCCGGGCG
+
?A7!%.!/9C4GB)2=7C5+4>F64/-%*&&31!)D69F#E&"C7("G4>)1(!*0B*;7+-5;H,E";)%$3$2+;!(9,#'AD(>6A6+5'*EH%1FB&)A"G5@(?"389<*>*F3-D$8<%;4*</1$5*&-#?<=613!2('%63/E7+9()'<+EE()'F<:E/7BG4D0
@r1855
GGCAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACNCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGAGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATG
+
+"'')&$!%'$%&!$'#$()%!#!$%&'*&"&"$(+)*)"*)$'(#*&(*"%'!'##&*!**+%#+"("$&&(%!&)($*'($+"#(!#')"#*(*"$*)&*!&)+($"&!+&%$!%!"'!(!*')%$$"(+%"*!+&'++&$#
@r1856
ACATGGACAAGCTCATCTGCGGCCGGCGTAACTCCCCATCAGTAAGCGCATTGGCNCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACANGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTT
+
-)G>2!;?+A&@(G3?3(*8C@A+/43C767B'C<:%65=&A,5B.9)@7!;@F*DC/8B,&@<;@!!A??;5D%7BD?E,,9;3EC-6!F91@%<=F5%&*F$29/F4&C<0-C+"=53%<G##$3/-F7B1%5?H3+767$:AH=D?G?H>7E=.H+G%+5-F(02<#/C,?;5+@7<29:1GAB
@r1857
TTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCNGTTNAGGTGGATATGGGCCGCAGT
+
<%@'FD'!A=HA$$#9"'@1">6D?BG.B9@FC9:"7H,'3+#;&86C('-)7@E),E:C/#,9>$$D3*$/4F9+:
@r1858
GTAACTCTCGANATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTC
+
,3>22,";>@";4B7!+E++%2=<"#4/43@1&<GFEGB>$!H(?/>3:(&'<C*
@r1859
TGCGTCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATNACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCNGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGT
+
'GB!7'E5:HF8;7F#$.)F076#DG>@>%+5G&G:3.$62.!D=!7&6$5D>8+4FB)28%3;2.=)"$<(83!,=,(<:<%6.0-4FC#"F74@4H5;:62;6<9">8,(B@+8(A(3,H%H//@;6.<<%#20%5+4:?B3.A>3#:(#9=HH(4):"BF-@>G#,8:$@57>1:,+DG,/+G2)65*D*)-&@!6DB8;DG?BF14:&"(#%F*'-EF4A"-(%"EA&9?1H,8(3G=FB+6E>%;&5A$;+#B6"4(9AA<D;-45$87:&,%=?=56=%<<*>
@r1860
GCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATNATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGC
+
38-/G2,).D&.H)2F!%@";9DCE0$CB(;(9E57D==H"4.%1'6DB$?0B';A3'F$%=A)5;AD6$1,)F:5.2*./7DG?->!132;F(/*@%@@?8)()FG.1'/@B:-!#
@r1861
NTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTNGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAG
+
!2+9=?+4C2(E><:*5F;($E-1!-9*,G1?06B?.C<&AB07F-91(F=;@46)?/G1B/>:)525/5$-)#883:.3616'HF;!FCA!$=CH7<=5=$*>2+'5H@7<!E!)H8-57C;0-4.+')6$@%&41$93$E)-#?$*3?G%7'B:E$8C6/+=(&>-1"8&,G(58+>12A)G,65
@r1862
TGAAAANTNTTNATCACNACTTAGTTTTTTGATAGCTTCAAGCCAGAGT
+
!!*"&)!)%')&+!("$)&"&+&(!$)$)%!$(!(*#%*%&+!$(&'!!
@r1863
NNNNNNAACGNCTTNNNNACTCNTNTGANNCNNNNAANNNTNGNTNNCNGNATNNNTNTGNANNCNNCGNNCNNCTNNANNNNCGCNNCTCCNNTN
+
#"$!!#!$$"$!"!$!!##$#!"#"#!""####!!#$""!#$$!#"!##$$!##!"#"!"#####$"##!!#!!#"#!$!!!$"#!"$$$#$!$#"
@r1864
NCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCANTANTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCG
+
!/:A$-B,H<3-A?@4#**85@A8440D'5)+;;>-+7$5()?=C$-)/'=(;&;#@B)36(*2?',:!FBG.7@(G;?E3477G6B1D3=
@r1865
GGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTATGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCT
+
0,68:E++!$*)93C;,"=>;.D>"*.(+>@.>$"96C,&,H!787#<2@6.&149HH>-#<<5&?">)>)=;+HD=%2</:3:(-;5#D@1!8C:.F>9;C@#3$0+4<*1G6C298:G)),#A'?>+8@$&!C0@3DC*$8;.5DH$5;A#A+#$D;5>#3@9$98-GE@87-EG"5"+1%B*353DF(<3)65)7/*!8C7:DB8(E(G0"0!!.E(!/$B?E!5/=$G&1)%+5-A><F'/H>1/<(:"075349D>1),'H1"(1D==-&44$?B*31@E@F><DF-&'0D#;D<#!30:96@>FF':')1,;H8=47-F2
@r1866
ATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTNCTTCAAAGCCGTCAAGGAGCTGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTGGGCNAAGCGGTGTCCTATAAGGGGA
+
+#2!D79H2%:*?0?)64A(@.@09"'/82@?4?)7A',8!65=2136+6EH<+%G!.4=:1)/4!@88+?A560H8E$%F+++?'G1A.3'6711''D+;*2&!8*<C)H=H:($*(DC$;H1$B,#@9)#CGF3/9>4<H4EB(4;E19<3:.+(EG;48)*G.0>D0:96D5#?"+>&?0
@r1867
GTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCNGGGCGATGTGCTGCTGTGCTGTTTTNGTTCATCAGTGCCGAATCANGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATA
+
,C<(4?>+D.;9(F@8;@E,?A:<*,"#A?(B"0'.&:$)?2<1#;D'"'?2-E##C:>9-0)=:*-8D/G@8$+&"*4)8?+D/?730DB0A4%@/GB.7-E-@/G0%3.?%..:?C%FD0?$8!4G4DF0-(:&</:H86*080=3=-D8A73).?<D;:
@r1868
TAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTA
+
'+$&$''(*!++%++#(#)%&&!!#)*)*%%%"(++$#*")+)+'!(%#)()*'#%$&!("#$$+%"%"'&'$(""#$#!""&)$'#'*'**"!'+!)"%)$*&(("(&'&!+)++%**&)#$&"'%%)$%!&)&&+#"+&(+"$&$
@r1869
CNANTGNGGTCANNTNCNTNNTTNNCCACNCNNGNCNNCTTAGCCACCGGATATCCCNCAGGTGAGCCGTGTAGTTGNAGGTTTTTNCGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGC
+
%$%!%#$(()!%'$"$('$""))(&#)"'"(!$&$'"%($+')!"$&+!(&!$''++*&&&$"#&*%)$%)&)*"&#+($#!)%###!)#+($+!'('($%(**"&""&$#!'!&*%#%'(")'#(!*#)"##*$#)%'&&!$(%"(&+'
@r1870
CAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGA
+
(%++("$'*%+%*&#'"$(%*+$")((''#%!!!"#%+*"&'%&+(!"*+('%
@r1871
NNNTATTTTCNNGATCTGCTGCCTCTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAG
+
!!$*%#$%!%%!#(&&%#"#$&'#"++*&!(*&&*$$%"(+&*!%#(++''$$)('"%"%)*+()+((!*)!!'*)
@r1872
AGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATT
+
->3B*@8=E->2A98!--%/!E.(7?/C3*H9!."5*?A<.,74HD54E"*>5$!-2G?D)/
@r1873
TATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCA
+
,<H=H@DE74>!@83A+<DD6+?5H;"65!.=&#(,278/BC=""-4@<G6.@82:075
@r1874
TGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGG
+
&C?H>"<H'173+F4.#-/A62>61!/.B6&59#"!>8E.;4+1-9>9D4?232F?-G5?#'2%D.40(%E(+6EF#<$&D-#79:0?:%&=>223E<%,,#3GE-/=(9/5H8,;)'&A95>(!?.#?E60%5'E5F+3;+A)C;)$+G.3,1+6(<()-B*0+2,,7:=<'D:20G:;F744>9F3;6!(
@r1875
CCCTTGCCACCTCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGA
+
GC)"%%FH3@,-F#C29A:D740AC#)@*%3?F;556A-'>-6><H:2=;$
@r1876
ACCGGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTTCCGGCTGTCTGGTATGTATGAGTTTGTGGTG
+
$E71BD*.F;$9FB2G;'C097,G$E)#*&-803?2C!EH'#,$!!0.-0&4,G07E:76*=H>/F#7%,0A-/+
@r1877
ACGTCGCNCAGAGAAACAGGCTCACTGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTNAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAANTCC
+
C9-&?,B1=5/<H&E6EE)2=4C'01(B.H?H(6,=0+DA@:F=GH5!;<G+-&*(067&:A?#;E:5C#%=.B<#G*4GA!8,B1$BE:B>;;%='?&7H!8=.525E=H<>FG:-"*+:='5F7%,1;)9<3=
@r1878
AACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTNGTTGAAATCGGACAGGGTTGAGTT
+
'",>6GB::'0+?6B2<9D5*'->'C#H!1/1--B3@4=#87'6>>>%<B?*'>2$@29&/-@$#E1FHC'1.(;#9$1008,?'?
@r1879
AACACCACCNTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCNCGCTTTTTAAGCCATCCACCGGACCTT
+
D/B>0;6D873#(H"4H/0E+.(-,F*2:3'A?(;*9:6=9(@;84C"277&6=>+%(*3$*'D<G"32G23)0.1BDD@HC+791*9;?EFG30)H
@r1880
GTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAA
+
G<7%.!1075@$9>'#+1*((0H4+0'+2#3"/82E8:!D&7+52>)D2A)+B9>:.:A1(&4@&(#C49:*==88"F<'<3!+;2#?%%48,G1G!%G1"D4"#A/"DG0,75$@*F6/%:6!HC9C#4%,6;."1"ED!76>@'</74A==D.15!98GE$
@r1881
TGAANACNGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAG
+
FF/-B5"4:1%<"6)#1?(11,HC(=(F->2&>8/0*A++5>$A)<95%@$+=''
@r1882
GGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAA
+
(8).3B7H:?C?$,E?A2GC/0F7A)8B&E<=H,6%52,1"#%</%:'!D22)*)8/E'=)4<3(:"98A!C**&(:.-!41=C8%%;<#H6=?-,:5+&A=$?635-!'"$D?A:8&,B#<-"*?-6F>$9#+#9-)/F,H,
@r1883
ATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCANACA
+
>2F:EB"<D6>4B(.3/"AB"1H1E07H<6@8@3?A@#9D-);(#?<=A'05=!<@$(5?8FA/*#@E(+#5G:B=*40$B94>#+!$#);.$(,?!CG1!32<>:H<7$!%D")-!,;$+;/<3)+GE17?C<!*BG#(HB8H?=AA@#'5@3H>:A?,<+-B-->.B2<9;*!.**7EA)&0*EE7/2>/E/4FB.(7A5%.6'#F7560F6$'"E"<?%C'2F%"0/!/
@r1884
CGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCTCGCGGTCTGCGCACCTATGGCTGCATC
+
B+F'+"D;?!</9=H0E55/(G#D!E@)-7"'=/>&0&-C"H.31D:!+/=3BFF"8A&%)=C.A3(8C(>4G>G/4-<0*@1D$$*/6CE1':29
@r1885
GATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAG
+
4*/81A&+.<"B95*E+0)!6+%0%H?*&24,0=)9@=@2B$D/-"+F*$7='%).9:)=>)8?D/;
@r1886
ATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGAC
+
)>C-=1A!H+BF+/,?'<7!<CB(F';=A?"!5+6E*>G%'HE/!%HG(457-<-*95>;F%;F<2>
@r1887
AGCTGGTCTGCCGGGGGACGATTCATCAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTNTGACGGACTGTTACACACTGTNCCGGGATGCTTATC
+
$+%*$")'"+$%!'#('+)!"(#!!*"$'&!++)%"!))%&%!%))#)%'("('$+&''*"%%*$!!!*'&!#!#&$$()&*&%"$%*'!"(+&&&+*+$#'*+("($(")
@r1888
GTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAT
+
-*BA+$$!,@H73.;:80)F%"!05<BH?.3:'<5C;?G."(D$HE&!B005'F
@r1889
CGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGGCNTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCANTTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCNCCTTCCCAATGGCGCTCTGCAGCTGNGTGTTCTGCAGCGTGTCGAGCATCTTCATTTGCTCCATCACGCTGTAAANCACATTTGC
+
+:(*ADD-+/'!H$#F6>-<;3)9$:"D+&7=5%(2%2<7*1&<,8C6#FG5CFE525AA,+09@1:)%.)43D<3"(@30?56-'G&'2)$1'"3<,/5BGEA%#F":3B;4)22A*;<1;D>(0+A29331H-!/>:!H''$3FD3+0#/576-6?H!7:,B5#E3";D#@%@@DE7@$7*20-H-%!,7,D)*D'8*E"=0B&@"$(,%!'$%;C.*@&);8),-2**6BB?B&&*G2:(#61G**&23.;53")?31D.7B!H&#>0&:>3AD=$G;$81.$!;488;E$,)H:*E*7C:D3>B2:+*F+7E"!F<%-7B?!B(!FD;4-A%%E,1=E?GH)=A<2$-87<'4G2H#&:?;901).43#)73<(95>H9??*$$A.1(F
@r1890
AGATAACGCGTGCTGGTTTCANCCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGNACTCAAACTGTACCGCATAA
+
D8$+G=4B#"&.E$@:(>&/$$.,**<*+#-E51'8%93+79D)$-"<%6%G'?<@4=C3.D0)8&>.>..<E#5B7(6+D
@r1891
ATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGC
+
H=426*"G'%>1HE=;"*?>$/0<+@<75)'@(>%%#7F.*@3@(8C!
@r1892
AACCATTGCTCACCACCAGGTTGATATTNATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAA
+
"+%*%&'+))#(!)#+'$(%+'"(+$!%&"&*!&&*!'"'$%&")&'%('"!)&(#(*)(&++")!#($+"&")!%'#)*
@r1893
TGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATAT
+
,A$!<*;8C&$"0F6E/<H%//>:2*>+%%)18#,%>?E%4'8.39$922-;5>GAD<F(?=@,96-C:;0+07<++!'$10C7"E3/(7'2/,1>1C(7A
@r1894
TNGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAA
+
/GD+C,@8CD8'=&9&77,@A280:%#D"?:8F6'65G69B&=4H3;
@r1895
CCGTGGATNATATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGNTCTGCGGGGCCGGCGTCCTCTGNCTGTTCAGGGGCATTATTCACCACAAACTCATATANACCAGACAGCCGGTACACCACGTTTTCAGCATGNGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCT
+
;4/"=6F!D4<"?//(G++<3?)DC..02/%#9*>:%&-3;$#2;?.70?00/&C:4'/FB;=$((!49%14-'9FC&@3/0+)D*,(2)&(5CB#8-D-,>?F))$H2+;:/,"<;2HG$9-"-@F61>-6DH:)56*>'-*/8.A9>*86,30$-'#3!B*<-@;),G&3F;(,1*,)8?5+7#7EE;+91$D79'$@D"DA(.>>6=/&''-01#<5?C'38"(+C:D5,EC1H085<#'!<
@r1896
GTCCCGAACCCATCGACGAACTGTTTCAANGCTTCTTGGACGTCGCTGGCGTGCGTTCCATTCCTGAAGTGTCANGTACATCGCAAAGTCTCCGAAATTACACGC
+
!+#%!!!!&'(#%')))+'#!$&$#+)+($#*(&(#"*#)))*+*%(($!+#"#$*%&')+)!#%*)*$)+&')$*'#&%$$'&!''#'#)('*(%"*++'$$)+
@r1897
GNCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTAC
+
)'C1:*H4D>'F<75'%@!@B8+)8C*%.+"::EA9;+%7)H*G:-63=6"$9@A%.'GD$B'A8@(..%)1@H$<!@6>E%F/4G+0*$?66;C&%HH!G=/"FB;/73<*%4::$C3!*.76?18F<0';)>"(.621*!6?0
@r1898
ACACCTGCACCTGGACCTATCGCGGNGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCG
+
)'+&('()#'+""&#+*$*#%$*')$%"'"*#!*)*#*##"'"*&&!%$'$!%(+)&%"+"(++(%)+&#("&"''$*#%(
@r1899
ACAGCCAGCAAACCAAAACTCGACCTGACANACACAGACTGGATTT
+
$A:>=#@*###3!&G-62<0;3<AA)07"&8D?G>2:=$=6F&1%-
@r1900
ATGAATATGACCAGCCAACNTCCGATATCACGAAGGATANATGCAGCAAATGCCTNAGCGGTTGTAAGTTCCGCAATAACGTCNGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGANAG
+
5'BBB5!4:1*#E#=94/D<#;)EFG!#!06@15<!'09'6;@E&@>)=7HF1D<HA+GA2@3H8&<2B(9C%&,)C;%'@30F"-6:$B'!E:/%%;61&@?-;,.'-4;-C'!G=-*'3&D@C49-/9&!;CA;1$816<9=/$
@r1901
ATTAAAACTCGTTCCCTTCACCAAATAATGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAANCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAAC
+
9/-24!.H)D5D//A"-33BC0,13B1"8(A$$/1;1!3<.CF)F?"8D,@D*7-H.ED$-2D&D'AA8FH,D!?9FG61C+(!,8>A5(6"@%#8G3"'4@'746C%AB1H/1;E(B.17H2=9;%43>G@)9&4F*;F'(1;;1:+@CB-G?3AF@*"4A%/5D#/,BC99H?3$)6HGF
@r1902
AGTTNNGANTAAGCATNNGGGTNTCCGTCAGGCAATCGACCGTTGCAGCAATAT
+
&$#)'&$!(*&(!*(&"&&&%"(+)'(''"*%"""+*+)#&%&$%$'))+'++&
@r1903
ACCGACCATCTATGACTGTACGCCACTTTCNCTAGNACTGCTATGTGCCGGAGC
+
:(,0*6H=$<*E'&D%GH<<<46'0G*H58<&''2@&>&-4)/A2!3<%)!D*'
@r1904
TNAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTNAGNATGGAGGACACGGAGGAAGGCAAACT
+
%!+#(+!%"(%"#!*#+#$*+$('!($(!#!)$'%&)#$+!!*&&&"**&+$)'*!%'&&#+(*#)"('##&+#+
@r1905
TTCNAGTTCCGGAAAACGCCGCTGCACNGACAGGGGGAGCCC
+
+)%'$!'%(!#)*%*$'#!)$)!#'&'+)#!!+!#++++&+%
@r1906
NANTGNCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCGAAAGT
+
!(""(((+#"$#("(+'""!)""")!+$!!"$%#$%#)'"#!!!$'$'*)&+((($!+*%)!#!)++")"*(*#(!"!&!"&&&+"
@r1907
TTCTGCAGGTGCCGTCGAACTATATCCCNCAGACGCGGCAATACAGCGG
+
12@*%C)8</78=+6@H,*5<*''.-..<FA$=B+<@?5%4+(*%0367
@r1908
CGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGG
+
=-D#C5%:1$34*?-/+(E'4$/(2:H0D)&*>(6(5C//";%&F'18,*2DC.;G!)$1.%#=F1-#D(.+8FCB<'0'$@@(8%+
@r1909
GTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATG
+
><@6+?3;&.($"@-"/9&9<'0E7?H,8F!;3)B%731>+!%),92B!F4(*)27039!7,6F((/0
@r1910
TGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAA
+
>?+2!?4?A>92$3787"F&C3@)7-)#0$.66:#(&EAH0/($G@8)?*@
@r1911
GTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACNGACGGCGTGAAGGTAAAAGTGAGCCGTGT
+
4<=4BD>8BH*-0&FE-;@G3$/:</E;6@!-E6F=:4896@"";!D5.8;7!#?6.3!@<405=>.
@r1912
CCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTT
+
4"9)5F7E=G$3%7233G:CC,(%+/4D*9!/;7&#3*;.",1
@r1913
GGNAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCANACCTTTTCCATGNATTGGTAANACCATCGATTGTGCTGGAACTGCTG
+
#&$+*($$"))!$"!++!'))%+%#&*%+%%$$!!")!$%$##!&%*+)+"!"%()&&!''($"("++"&&)$%!"%(*"&(&!*&))
@r1914
GCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAANGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGG
+
CF*6E5+,DBD$&@<-B3)C:F/3**)+=$A25'?>CB83D&>B(9C&49HA)-FE!1<G708H:E>D-:%E3(/$+BG9=&#A:E%"8C#"<$/@50%>9B:(E6/CH50;427C=?.=:%B%4"%6(159'BC?'63F8H.8;F*BH$2/5H%76?%3B&,0.<-2&DCB(+4
@r1915
TATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTANAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTNATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAAAAAAAAAACAACAGCATAAATCATGCAACCCC
+
8":<8!834(2?,D-#B'CF-!&)=;68<?)#@#D:6B$1C:6*0,/G=8G)?(C5&H5&#)94,E>B3>36!4G/E99.%,E$,='C/"1(&7&GG&D?A1!B0-9')F=E>$>84:0*/H/#E5*!(*-3%>$0"($!8EH/D439H3)@F/7E%E/:H):;GB2123,.)<'B@-F.?G-D5HH&=,0!B)EA$*)@<42$'D<;:@<2B3:!";$176HHD).50D")FE/%>5(H:BD.,#1,<#@%='11!E9B-*7:G@/($&>=9B"/;04G@5)6+7(
@r1916
CTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGG
+
*G>&HD<@,2--D0D)A$./93G7.9)@-%>%D?3)(-9)B1D'&$
@r1917
GCGTTCACGTCCNGCTGCGCCGCGCTGGCGATCTCGCCCT
+
&'4?!(/"<>B@"0,$2A>'.B*1%"%H0#)(0?2DB=;?
@r1918
TATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATNTAAGTCGCTTGAAATTGCTATAAGNAGAGCA
+
(6<*-)5C4B5D;%>C-38H8GA("@%)B1'4079*'*46C#-@5.5A3&E!23*A?@2=/9$;5':=$207G.G-B%6&G6!%+1!G6'5;3"4*;G-A&?=%!278<D3/554B,:;.?>E@-=G?HA+9D'*C*
@r1919
ACGATTTTTTCCGCCCTCAGCGTACCGTTTATTGTACAGTTTTCAGCTATCGTCACATTACTGAGC
+
4:4B/77;)6:A)<'H7.EHB46#-&D1G3=!6+:!<A34)#59!E8/-5,-"1"7B)C2*GC%8F
@r1920
AAGNAGNAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATG
+
$*##%&!++!"!)"&%#$'($"%"!##%$)""+'*$"$$(#'"%%))!)+(!#"(+#!&'"!(&"&'#&*")(%)!*"&%$&"''
@r1921
CTCACNGAAATCGGTACGGATNCCNCGAAAGAGCAGATTTATNNCCGCTTCGCACTGACGCCGGAAGGGNATGAACCGCTTCCCGGTGCCGTTCACTTNCCGAATAACCCGGATATTTTTCATCNGACCGAAGCGCAGCAGCTGACTGCTGAAG
+
)*"'#!$*)+()!$#(+)*$%$("+!)$&'"'")#"*!)#!&*""%+*!&%+%&%#$""'%)+$+$*%)%"#$)$*%++#&"(&%$##%$')"!"$"$#")!)$!+"&#%$%*+"#%)(!"&'$(*#&()##+(#*&#++++#$))+#("(#!*
@r1922
GAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGATCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAACAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGNTGGAGTG
+
=%,(3+>8H9!.3><(A?05!D4)>)4#!"6,*0A!!1=/!.$H$2CGB212<"E6+,"1"6+)#C2F-$F*$A':<98B(5"4#''&3;(AA=2,6HA8EE)>*'74.?9=5%<(!-607&!)E;6"G=/6'H+H$B/323%+(>>F"H8(&'"=A!B=2*0:26.;'?4(51F."@B>>08?1<1*-..($(**+4/@%B3;E%@3=<>!07A4!DG;'!C$%E13+>@>*H57?%F8"2G<A#C,(-F'GF$6+308-=''0A5+B3#!)%D63,D'6+<#2&C"%54**18*F/G+7.>4D2:D16C)++B#!&0*@$<?C=49"AH5D2E4E75,F
@r1923
GGTATCAGCACCGGTGGTCGNGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGAC
+
G3GD#HE!;+4*:*;B/)@$E?0)090@?C151=?=8F*&9BH8+*H.:@'&::!/!8:B<&&
@r1924
CATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAA
+
@9-G2"!+33!H/:EB8(D1%E(#;E?EC'-#A()5GF%(./::.D
@r1925
CGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCNAACCAAATGATT
+
+A@GE:47,,!B4??G!<E:!G.8GF<418'@.>>9-;'-5DGE:@)4/32@00?!30H
@r1926
TAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAG
+
%%/>G01<;&<C&B9-DB(&,F%''6E)E&6E9,E4%&:(&0F+B8':(@G4D:#.=%E"+<%8>1576F#$E"@(!$?/<"@@@@>=:@/2)
@r1927
CGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCNTTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGG
+
+F@+;9.&/GB!+23$/G%;D2$22E-&"1;,=HA5"@:CC>E>)3>HB!F&9A.,C))'C#G9,56D((44@B2"$'5/&4<3&A;#1@7%1&5#00=519)56BE/,+B?$<827-)=*2&(=G)?'=;B74
@r1928
GCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCANCCAGCTGGCGTTTGTACTTCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGC
+
8HA,=17=B-+.95<*5D@?2#:%E/";"?5>H-$3A3HF)A@A9*.'.-4"996!+2'>2+(0D/8=%0ECC'*=!CFCB&;FD8&<39D:'<8E%0;))+2H?&E@57-:8:G7.$@9@!='5-!H91B0)(>C%>E15D"B/0H7(-#5H:618(3.&)2*2H8:9-;A;C,B4'>6&B)D6/>+AH%*$H1!03)C/71&H38/
@r1929
TTGTTAAACACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTAC
+
3:';5"1D-230(&-C8?1%G&.5B0"8?>79D<@31-4$-F.H"0C,6,.+"3@+.C=1&;F'0(/%;9/,D-3523%
@r1930
CCTGAANTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTC
+
6@%9G(+14BH9=E#?0=G1,.AC!55G6+"D=+G+=H2@3B7'3+(AD"A'-@10/06(-'
@r1931
TTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTNCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAAT
+
G7$',!*4H*#''&,&$H2<=!-HE17">7!"A5@=*<1<7:/D("'6*6F4%(D@5E%&>G71///1='?82&'&$6*E+1AB,7FF8+017&2-7.H,-=1D:@6CC&-2B"';*1#9'10!"1@@CED9>
@r1932
CANTNCNAGNCTTNNNNATGANGAGCAAAGAAACCTTTACCCATTATCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGC
+
'##($#!)%!!!)"!!%%#()")+!%)&+('"+%+$%()(+%!#"*'("#&+!$#!+"%'*(*))&"!%+)++)*))$+)#**'$($$%'*)!*##!&"('*)#$!+"+%&%
@r1933
NCCGTGCGTTTGATGAGGATGTTGAGTTTCAGGAGCGCNTNGCAGAACACATCCGGTACA
+
!B=8"0="D6#4:?-C$1;5CG%HH6<,DE</"4D09H59#>HB*C>G@HB!HDA0C=2F
@r1934
GATAACNCGAGCAGNCNGNANNANTNGTTGNNNCAGTNCGAGGATGCTANTGATAAGTGGAATGCCATGT
+
#(#(&*"#*&())'"(&%!#""*"%!$&%(!!""$$""!!$*'(#'!$#!'+)%')'%&$$+%&$(+$++
@r1935
GANTGATTGGTGCAATCACCAACACAGAAAACAATGAATATTTTTTNTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGG
+
$(+*!)'&"!%"***)(#*"'!%*$&%)'$!$)&#&#'#"&))#!&&&!)*+'$'!"&#'+**)+$$'(*"*#&"*&*'%$$##!((
@r1936
TCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCA
+
D>--2.%&F<7D#0*G62999EC",>B86<)-.&A+/3@D<@(G2*>9&!E0
@r1937
CTGCATATGTTGTGTTTTACAGTATTCTGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGANATTTATATCATTTTACG
+
G!/<&?H)H62B:4?.@'>&*<?!-B,,9B?=2D<"&'42!,8&14B&":*446:*+1<F>&:7!2"64>/<+('G"?>D8*=#'-
@r1938
NAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTC
+
!%3GC%/<FB;%':H"'$#>3'6">49!=/<B!?.+2=H5$;$11A9;G7>>':%H=26B$DD-
@r1939
AAGTGATTANTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGA
+
5+!.019<3206!,9A@A&)A<?@.0!H1:7;?5'55,!D5F6=-)E-.G%13AC;63;!;G;./85'C89-,E/B0.G&9,:$&,,$&$'G%B3#&=.3A@2H7D40;>A0H;@611@F-/$!
@r1940
CGTTAANCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCAC
+
$)'"#&")+#'%"!$'(($+'()($+%'#)%%$+$(%+!%%*+$$+"(#+'"(#
@r1941
GCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGT
+
718<1>;@".88!;D+:>;)D=8<)-/!.>$&$G6(.*!-/+5&'#B$&@
@r1942
TTTACCGNNNGGNCTNTCAGCCTGTAGTTCCCCAGCGCCAGCTGCGTGAAGCGGTATGT
+
'($&$&#$!")&#'%"+%+"!#"(%'$$"$)')'+*!"%%*&$%+*)##!($%&"%)#'
@r1943
NAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGTAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGG
+
".F/!+)B>/?%9;+->F#=H6;877!D?>@";H5DF/G@(%B.)>HB30*7"</2++0%6D)?19//@,8H%7<:DA'@EE:3G>.-86;1"ECE"0".6#!<?9HD=+#A$")!'#H2HH#7A$H1@0>!C*+66H-.=E
@r1944
GCNNGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCNCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATA
+
#(&($''$+)'+#(!'#(&(()!%+)!+#!""$+*+$$!+'"*%"))&%*&%(+!'(#*)&(%('!"(!&%"$)'')(&*&%+)"$%&#)#'!")+'&'#+"*#++)#(&*"#%)(%**)&%')&"%"((*)$")&$
@r1945
TNAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGC
+
(++"!$&&&('+*'%%(#))'"'$&'*)$$&$$%#()(&#$$(+&#"$)"+%+'&(&()'"""%$#
@r1946
TGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATA
+
CG&>=G78*18FGCD"3!5C&&5.>B-2<D7!).%0G,*3=A5-#-8+834?.40GE0<!B>FH:
@r1947
GGCATTCAACGTTCTCNGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCC
+
=%H*-0GF4"F-#-E-G%7C;/:F/*<49+?93G/#)F@-9/8C4*D$E!<"3!!<3<$@."?3;#>>.C06*C@3<*"A;H5/D1&F</BE!?0"B3"
@r1948
AATGGATGCAAGCTNCAATCGGAATGCATGGTTAAGCCTGAA
+
0(3@>?&EE7D0!G"*/H,":3*(333.6$;0*;,E2*7>/A
@r1949
CTCACCATGAAGCGTTTCACTAATTGGCGTGGCTTCTGGTGCCTGGGCGGTANAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGNCAAAGTCCATCNGTGGCTCCACGCCAAAAGTNAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGG
+
0AEA3$6)((F'B+&7,.8GB0,/@<A%.27&701+?91?7@@#'%%8/8'C)@+/%F%@!7E3?)2)==&.)=?GC(4'8"G2#8<68-4*/C/>3F0>56D$A"><>)+<?D%5:G!/>!6!1*C88%B@4%$&"<C51D&&86G'.#3*7F;(?4@:6+>/"07>8;EG"E6!A)H<132$0.,1B(?/(3;>=.E?3##HFA%"8B@4B$F.18@.-C%#H6+8@9/"/B5%/><3&3=311&//@98G(,5#F5.!DE&,2;F$H?,9"03>,""B:F!1+=D.*..F@E>&C%;F.1"13E0-)(E<H=01B=09(E0&@DA;G&>/(>/3H#HE>;2
@r1950
TTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGAAACGCTGGCTGNGAAGCTGGCTGAACGTGTCGGCATGGATTCTGT
+
;A'D@D8&&!3>+#)B6#9C7%*G-$<,%'&37+=(4',63?2-&*D<+H%$0+G<,=#83:>@+62>F2)$8(3<D*0E23(6
@r1951
CTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTNCGATTTTGGTCAATCACCTTGTTTTCCNCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGA
+
A)@G=B9<=+92E51C-/?11H6"29-841!G>>7/F'/-.?4C1E%4E)7&)E@--"<1$=D(7'!>:?;>3*"A=C<FC%<?0$A<0++B9325/BEH$G,277/-1#DDGA4A5>+&?"2$2@!"9F&*/@3G"'5>:%@@$),79>D"G6$CCAHF4D71.?4G:A/.2?F-:%*<);:&.D?+H$"$5-)4@;?B$#7>+-@**1>&',
@r1952
GCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTT
+
&HB@2'%$B):/(#>&/317=.@A5A&1605A38GBAH.9AED+8A28.#H&D1<4:
@r1953
CGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCANTGGGATNCCGGACATTACCGGACA
+
1!?)D5>.DF/74H:!,#".5C:&/;:G<@3+>/A5G7&;!538C3-CE:5,,B-6)55+CG0,*340?
@r1954
AGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTT
+
C!G6%/&844>",A:6'@;!<:E!/+>@/0,<:>,-E&$=1:&A@B&A<6+
@r1955
GTNNNNCNNTTGGTGNCGNGATNATCGCTNNNNNCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTTACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAAT
+
%)(##$$(!$***&'""&)!"(#*$**!"!'#"$*++(&+%*"#!"*#'**+)#')'!&"!&***'%#)(''%(''#(+**("+&+*!!*+""''+)*#"")+&%#*"'#'*#+)#%''$)+&'&!*)#!$&')'$"&('$)!+''"'(#"&&%$!%+$(*"*$%*)%)&&*$#'#+**$)#
@r1956
TCTCNTTGAAGACCATCGGGGTNAAAANGTCTATGANGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACNGGAAAATTTTACCTGGTTATCGCCTGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGNGGCGGAAGAAACN
+
%$'$!+)'&&(($**(&%*%+'"*%*#'&%*(&!&$$'"#'&&!$#+#(*&&#''%)'&$%"%()&'*&(+%&%##)!!(!+%*$#$#++"%*+*($*&)"*'+)"$)(")$!%$#%&!(!*%%$*)#%%+!%&)'!*$'$)%!$'&!&%")"$+!&#%%&"!'"!'*'!*)($+#+*!%$*"%&!&(#$!!+#+$$('
@r1957
TTTCTCAGCCNGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAA
+
*-*%/C9@&A;3-@&(7;-'G/H32C#$(</2D/GBAD5"!B<3'C,"A/2:=)207C/0&53B9!3(
@r1958
ACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTNACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCNTTACCNATACTGCTGACCCAGNCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGC
+
6;",B<0%041A*">E!8"?+E!0%(3C10'7!,"@.7!3>%,$%DD7>4#3;7B/@24347#>.:/5#&F7?2>FA@+AA2E&.!7.%.#2:<C-DA:>6,1C01E+'-4!,!:%D(C16@.,4$?+!>:GCH#CGF"'EF'+/,36GB5!1%B%:,/A'#*G,.9H=37>*$%F$)=&@'1>&BFA!01G$%@'#E
@r1959
ACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGNACTTGTCACGCTTGCTCCACTCCGTGGCGCCGGACTGCGNGATGTTATTC
+
?9G:@:+G.<G!<5,(/)<%.(EAG'/,0-5.'@6B!=7+'4-29+%H(C,CF1;?0#"C(=3+(<HD"(&/!5"<@9:$+/)!#4D"C,"H7!)+)-9(;.7+763!=!6.?6)@*&2*.*
@r1960
GATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATG
+
2F>H4%#=('A94-<?:B=<@8('!(H14/0'$5:(D(999!
@r1961
GGTTGATATTGCCAAAACAGAGCTGNGGGGGAGAGTTGTCGAGAAAGAGTGCGG
+
H&2/8B;6A6%<4:=;.FB9G*H#='-H4)&E3?;7.,985*&:<9=A4#;4(8
@r1962
TAAAAAATGGATATTAATNCTGAAACTGAGATCAAGCAAAAGCATACACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGC
+
3!D$F"++-@<E@B/&$=,(BD"G3&-G9>6,&;F0.>0<<02C?<+28@G3A0D.B(<8@D=*49<1?F804F>:91201,/=B=?@2:
@r1963
CCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCANGACCTGATAACTGCGGCCCTGTCGTGGTCCGTCATCATNACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTG
+
"*+#%!(&$+!()!""&"&*!+*'#)+"("#!$$(%*$)"$)""!%$'*(**!("')(&$!&%(%"%*%)+()$"*(%*)#)'(+'!''!+%"(**"'%#%(")&'%*$*'%$'+$((+$'"+!#!"&%)!&!(#"##&(()$')%&&"$%&&%#
@r1964
TGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTT
+
<#58D(6/(2%F"'<+3';/46""5'"<G$7#<&=-HE-,GB@EH<6(6*A?5#--H;<&*
@r1965
ANTTTGCNGTATTANCNANAGNNACTNNTNCACCGNNNAGTNGNNAGNNCNCNN
+
!"##"#"#$$#!$"!$"!!"$$"!$$#"!#!$$!$"""$#!!$""$!"!$""#"
@r1966
AAAAGACCTGGGCGGCTGAAGACCAGCTTCGCCGGAACTGGATGGCAAGCCTGAAGACCGGCTGGAGTGAGTGGGAAGAGAGNGCCACGGACAGTATGTCGCAGGTAAAAA
+
14981"82$?H:9%4+/:5>.=7;,EA16?5@-(2=GF49C4D,#0GD+G!!)($B;3D003/4B62/&.6$7:2@("<<5=6F);EGD>'565$?F:&8.:#$9:HG7H(
@r1967
TGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTNTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCG
+
?E6@10A(4:0(/><;48910./@"9%@D??A0,"G-;,#@?:A$E,&)'.?!;;@E#"0<,5:9!=H-2>;<,F!&27.G%FB>*,1%79@18FG<C;:.2-77H%&'9@
@r1968
NCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCGGGGACGTATCATGCTGGCCAACACCTGCAC
+
!=*32%7>D2;0/&H'9<?A+=CC7==15F2'+"C8;,>9+E(B8?9?<G5E-<C<FB01AAH94'*0>!@$#<:.E%:%4A9<C$E!,?)=!A?5-4C=
@r1969
TTTGGTATATNNATATNNTTCANTCNAAACCTGGNNGTNANCANCGGNTTCAACCNTG
+
))$$#("')'%%!(!*('%"*$%$')&&%*'&$$'!))!$#)'!#'*"%+(!%$%%#)
@r1970
CGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTG
+
B(9)3>!62&59?*/'$:D*4/$@7&@(/?-;'H3-B*>3;@&<7=-B,HB(B
@r1971
GCCGAAAGANTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGNTGTATGCATTTATTNGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCNATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGANTGGCGCGGCAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGG
+
8#<2H$1@%!>/B<B46&>CD@5=5)38</4*:%7HF7+AB?6/GH0>9DA8)"EC*@/AH"GB9:6:@0B="%8>>')?'?+*E5:4,370,56>=>3F2%D:@E$)*>;=&G4@A=-D")&0E@*?F)=E&4.09*,D-&/4B(0F2*,B1E?9,.G-F0*97D/03#/=%!$;>$?D953=HFB$6<6+2-->.80+:=.F*'E-@&<7'A!A+#G6A#;FH4"37,0D$9>E$H,/52H-1-A/0;+>(6AD#=*!G-A5/?&F><3";@08C9=4)(AD(7C#E>7>9%!@D>07H@#7?DA,;+1!2G0E";B4/FC>@-(+'FH;!;8)FA8()6/&*+F:+:115>7&)'@=&DE&$(+9",==><'$*52G&&,#3&2D';7?1663F2##;?A(@!G53&;"?06@BE6H+AF;=6.<-9859D0'>61C$)#&15A?-#.:+>)H/;,3GA511@=,/5;
@r1972
CGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGCACGATATCTGATGGCC
+
=1;F%9<1C7!",1&'<C!>:-5,68$4.B20GB#G0BB&#0D(<=(<58%H'1CF,>""1?7G#<5$#62H6A)3&54F!-E.
@r1973
TCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGT
+
)+5@@90+8<+)3(23=%61))A5A/=C72(H*F.:!',7?
@r1974
TNNATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCCCGGATTNAGGCCGTATTGGTTGG
+
$"$+&'$))!+&+)*)(#$"&*&$+)!&&$$#($%#+)"%%+(&!'+"!)!&"'))'(%("(+(&'$$!"
@r1975
AAATTTATCACCTCTAAAATATATCAGCATCTAGCATGCAAC
+
=H5:<9H/DB6'&<C)'-'4;21CB0G7B%A*8&#/6+6263
@r1976
NGATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAAGAATATGAAATTTCAA
+
$&>$CG"B!*GE)B2!9A?6=7F)!*F7C#?G$B46@6FC:,AB>3@0B=G67CE,#=*=(/)/BD5!#A:B
@r1977
GNTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCC
+
*!>2"5!&&';!32$'13)1#"*:C2DD+@1*"FE<A'H%'3%?1,>:G643!6'<H1:2HGF/(!/@2
@r1978
CGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTT
+
:/E:*4=#+(4%H$D+8-67-?/8&0859,'D:05-@3=A+,<5=&941BFH,/9)55*D-:.2?-($'34;=/2B3G<05+BD$3
@r1979
TGTTCTTAATATTTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAA
+
D'-"'@?$CD!*",<D<!,=./D?;,?54=A%.,?A,8#6@G0&'7&4,02.&@4..:<)*:4**H1<4=!"F&9<5@-6:;
@r1980
TGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATG
+
37F7C;CBA-FA)@,>7.0D"B>/'>2?&2@5'C51@;A=B0+,-6'%"77+=8<6;*4A:-#A@8A<842%B56A"E?B)A2G7+6"=#0G-A6E>7
@r1981
NTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTT
+
"-329-(5%F,.),82$$-91A6E)#%!B98D8C0%'"-98E1D@A:'<D<5*GG39*";3?D+>2/7E&<)#53:#(&@%5$4.46@<8E&B7DD5=+C=D15
@r1982
TGAGTATTNCGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTNCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACNCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGCATTTGATGTC
+
$76//*00=+>:1%8)D#$(*H3$>5!HC"@0,/@C03H<!C+/43$G06B?/76<AH3%?27G598-CG''',792869)$:B#%D$>$,A<6D6/#9F@#:=.A2@,A#0*1222A&HH"%<6%;-;/C<=/<C$!>".$56<0=./:72G562;A&7F&0&=@"*(4<6$(8>!B0D2D>;($6-5-G2>28/G;$A!77E!H<!/3$E9G!.5'F60A?*;,9!#)%8'6C!H/4?A04&HB",G@$4H7-'14/0D-?!DH$==)
@r1983
GCNANCCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGT
+
)$%*!+&&($&*"'#&+*$#$!&""+!*#)+*++&##!)(%))**%+#%
@r1984
CCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCAC
+
A$$711%=CH%7B)!;%9,)#(4.!5C;!4/?AD>,;!36;:'$
@r1985
TTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGANCAGCACGACAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAAT
+
36/'D<B&C*H7H61B.>&8.57=9"F#'&C";&5D)=0"C/D,=?'?-B;*"(B)+E@,D.,;@4"%>#="(F:(5%9<<6@A<FC8*)'"E<)<F&;(1@!(4D'2.1??!'&,F!'<HD$,>HHG-?=0+?"!4+0;B45D/55226(=,G1+E(HE,"F
@r1986
CACATGAGGAATACCGATTCTNTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACA
+
8(EE!<A30.0->F&@F8:G!0"=0,'CC>9499?97!-)8.D(*FAED=B8<3!4%&05910"1F@#E+47/.#5421?!!9C$79'+.D,
@r1987
CGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCGCAATTGTTATCAGCTATGCGCCCACCAGAACACCTTGCCGATCAGCCAAA
+
&;*?8'>25*&)5*AAD'E;):)9<(5$DD1$(7@*?#+*:.53&@%?FE1%G->4E4(AA2E:78.$'3)D6;&.<-+"834-*6,<-=+<A@1H)&50"#G61">2D#*)9$'?F):%%8-+2)8CHF6'/="32*6>7$@6*F((?(
@r1988
GTCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGAAGTCATACGGATANTCCTGGTATTGTTCCATCACATCCTGAGG
+
";"<:-'*?12>7;'$CHEB-='BD'2&>/*D9"5!+!9B1"-1G@D%3;C-E$4E4321%.3-BF?24D?2/2.!B%%="0@/++C2:2-"24@
@r1989
CNCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGTTTCTATAAGATGCGTGTT
+
2:@A5;#D0!'>A:@-A/9G:-$**H5?1!)?9F4D'E!$='H.-0<63"(83G9+7,&0GCGD
@r1990
NGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGC
+
/(A0$H:-9H/A;<%!9D5(@;/,A49A(&(.+9*54H)09'?(6@8,4/7&F>+AH?=*"=1,!4B><B.=2!+3!5:*B1B-+B<9G?9#:1)60GB.4%2C;H:H$=96"C$)5+5>!0=E-F;->?4C0
@r1991
TGGCGTATGCCTGGTATCAGGGCAACTTAACCCTGTCCGATTTCAACAAAACGCTGGTCCTATCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCC
+
?B3C'F5<H;B,3<)H>%$4+29G8D.0).C*6321%2.!D6&8!&?(A//D!B22E*-@%;4&"6'5)F#2&!=*'73++F<"22*$D%98$#)9$,C'=3BG0:"-0,$&,36-
@r1992
AATGTCATATCCTATAATCTGGTTTTAGTTTTTTTGAATAATAAATGTTACTGTTCTTGTGGTTTGGNGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAATCATAAAACNCTCCATTNTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATNAACTGCTTAACNGTCAATGTAATACATGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATT
+
(E1B75!F%*'$E=*F!5=!8B%/@43254=!E/::-=FB,)*1980(E).!H8:/A(C1/C3'53)3F31G#*B0H&,45@,*<8>A;*=)7B<G;"@%6;*E.EB3.>357"2E>#5E9>&G";94GF%:+99$)23#;B4C/8&F#?;2FAH%<@'*19.G10:5(47$9#&:;20''4'-,)5H$,01:*,064?8HB:0>0@7*B"%G?-()>G:65=5#H<'+B/-<5(-?CH+E%3=>1-G".AH*6%!@!4E0A-:5-F.=9-'+C/(,G=38(,*"#2H56"C37?"AH>;-$(4FHB(*-<?='+>'"/'H22.;6=/DGA!'@&B5,>*6G(F1
@r1993
ATCAGGATAACTCATAGAAATGGTGCTATTAAGCATATNTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTT
+
:#'<7:@H+H<,2F&EG9#(2@1//80#@50'D039;=H<:46H@.%/'AE@9=3>2E';F"72H,A#(9A?<&1"4,F2@$GH7@G#,/:2$A#
@r1994
CNNCCNGCTTGAATGTANTTGTTGAANNNGCTNAGNNATACG
+
)%#%)#$%))'*%'*!$"&&%)*%#!&!#')#''##"+'")#
@r1995
CGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGTACAGCGCGAAGGCATTAACGCCTCTGCTCGTTACCCGAAAAACTGGGTGACCACC
+
<@>19>6!'.-D(#2(./!DF-4+(B*&#7:.=<E3G*/;-@3A46CAGA.FG?%;=:&@@#!C1G>8.(+,;GE0#1B!@:625?DCFCD:!0
@r1996
ATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTNATGTCCGGCATCCCACTGAGCAG
+
6C8/$?B'GG:8*/9*8&?'?#B"13$;:2:8CB>8<56!//=C?*009(%3F>A;$"(514"E//?G2-@
@r1997
GAAAAAAATCAATGGTGTGGACAATNCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAN
+
*'+""#!(&'#"((#&"(!)$$$#!#"$""%+*!)&!+#*')!#&+$"%$#!!)#'+'"!%+(+'&#*"*')+*())'
@r1998
CACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGC
+
3C.D@B-.D8;G+ABAE85"6>C+6@9C-H0:@@8.E1F,.68%/
@r1999
NAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCAATAACCAGGTAA
+
+&)C+=8C5EAE+8&H*9B@<960"1<0#/,+%:C.(7+28<A>:88$<<80
@r2000
NCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGNTTTAATGAACGCAATATNCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAANTCTCGTTCCGTATCGCGTCGANCTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAANCGAATCAAACCAT
+
"+#''*$")$+'$+(%+("(#('!)$&&&"+'"&$$("!'!)&)"!!"*("$+*%%*"''&!$#+%!#+(!*()$&+&%&'&"!#!!%*+#&'&((+#%&$+')')$''#+(*'$#+$((!&&$%)))%#"")$&$!*%#%(%"**)('%+%')(#")++#'&&*"*(%$+)+*
@r2001
AGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGNAGTAAAGAACGCGAAAAAGCGGAAAAAGCANCAGAGAAGAAACGACGACGAGAGGAGCAGAAAC
+
/!-F$/-/.1@A;260C)(#*+"4H*F01#"#2-#4+!?0?:G?,A46A2+0,A$5,GH9<A$&?*1+)%0;;!3'F0-*!48'+</-<"-;)-2#1B>H3;38G:F7(H-G%,
@r2002
GGGCTGTCGCGCTTGAGGATGCGGTCACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGNAACCA
+
,-679+C=6D>4B=#(!6*DD.0-?"(H"A5B91:>H!F+1CG8E8/8"H-9F<G9..2<2.+42H
@r2003
ATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGA
+
<B%9@C9%.HD6+<")G510*<8%H>*@-.H,)$&,H;5@D<F/)HC>73),B##D1E+G(9@=G9
@r2004
GGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACT
+
)+EF2H%#5@F0GF@C#6H9*@7*0:0/8<?DB7$?GG?(.H2/HC*'+H<-"1
@r2005
GNNTNNGANNGTNTCANGNTANTNTNCCCNAATCTANTTTNNNNNNTTGANAGTNCNGCNATGGCTCTGANANNNNGNTTCGGCTNAGC
+
####!!$$"""##$$!!#"#"!$!#$"#!"$#"$###""$"#!##"$"$#!$$##$""$$###!###$!#$$###"#$!$"$!!#$!#$
@r2006
CCNCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTG
+
FB#1F63B$<4@=#"FCD,@)D/@4(G##/3-1",%C85#;.F,'*97CC-+)9?F2
@r2007
GCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGC
+
FG-G:D)F$7@H%8E10)!B0EB+94)2B@70$#DB4;/CC$2E9-@!<CA7)0)#@3=B2-B2;45C;.*23/2CFA-"(;$:(B@=;<"G,*)@"</H&*8@A@(=7-'-4D-=A'C??@%<C5>>7(,@++F5.=F#;$"*'D%A&%.0G(7(H8G1A9=7E&,*7+,9:@54">A@'H=325:;-</<>E:'5*6H21;A7-:
@r2008
AACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAA
+
3A0>(GCC<26:31B@<GBB0":,?*63+=B2,/-#.4?&>4%*<-
@r2009
NGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTANTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTAT
+
!8$D-@'61;%@:5$$96%:<)4$$65#GC=C?"92C,8?6C*A%(F'4$2?(E10G+>;D3<$;5&,E.&A1+7?';7BF322CC>(?#!"-5:1@"D328',<72A!':C<H?$6)#6=B/;'&D4'2$93F,+'2&*+8HF%5)0%4/&4$$/+!G73#3'6G9$2/93A/-F
@r2010
ATGCGCGTAGCCCGTNGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCC
+
9=+-6+?;0*:C),3=%=BA.C'"2,F@";'F@,>>A-!"H66A72(-4+A$)GA.$G1#<0ACB5G.EF'0@"1&2"B7=90=:;&8F3
@r2011
CTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATC
+
D:"H$;HE-'C#5<HFH3#6:.0!F==C:D4-76/FHG.5G/&#!52'DGC(&E(#?7!%.=930-.D,758
@r2012
GTGTGTTGAACAAAACTTTTCCCCGANGGAATGGAAAGCATAT
+
H,DB8&6C5E.81-&/$D*/4"$H?&CE$19A43$CC58('37
@r2013
CCCGAAACAGTTCGCAGGTAATAGTTAGGGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAAC
+
FCG9GE7:3(+D$!2)8&C'"3(=1D?+/5.++7.7805'D?$D6")"(1G?>%EE9>#-@*-89%C!.
@r2014
TNCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATNCAGATTTTNCTACCACCATG
+
(#+%'#!$*+)&"*!$%(*%$'$$#("(*!!*""*(&!*%&!++!**$##"+!&+(+'"#!(*"))*)+!&+!"$(!$'')#%)*)"$+$
@r2015
GATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAA
+
9D$*;&*GDE0!)E'.=@;)?H65>2(-AB!8##A"*)>$,)<:
@r2016
GCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATA
+
DCHF55=;<>=B>-=<B6-=>6(9.<5?=<"A%&5@9C45482,0:?9,@>>+:!(F>@C:#D6E'EC.HA.A9H3B7:EAH+44#+D#0H"C,4@E@<3&?(3#27';83H,(2/59&E6E?83&396B92D'
@r2017
CNAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAA
+
(!(.!05DE>)>3(H/:9?-(H7,47#162"$&++.%4@$0<#G8(*/=)G@F?=
@r2018
GCTGCATTGATACATATTTTNACCCTGAATTATTTCGCTTGAATTTGAATCAATTCC
+
-)A&11#7@62!A&-@F:78"#$>!A;'(%E,A@A%2=:F,$'7E%+$@$A(?:/3!
@r2019
ANAAACATTAAGCGACTTACTCGATGCACGCAATGGGGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATNTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCNGTCCGGATATTGAGAC
+
(*$?B80%D2A4(.D'(0..-@)C!+@*.$6E5A(?D7)>",>GA@,!">4:7=-"<'H<D$H=:<B/A;<D61<1<?-@8:&#2*%*>0=*;,>G$G<?7#BD!$'0(-."B.B62E?/<;1-G(?"FH90E?C'&A+A<3#:(F34.?=6"
@r2020
GATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTATCATTTAATAGAAAAAGTGCTC
+
1:1C.8<.&:1)FA.2%#,*6+/7>7+:'='-:)2(7C:$=&0%F#9B4"G+0A>+;@GFC>089%'H)AH:+;=5E,E"*8)9G($*A:"'7,A-?$3'>)6#9*$*912C8.(.E8.5B'(>FCA,&D(<2!C'G1/'$$'3@0%+6C9D6FC88C@<:>#&1%.9.EC+6,=-A>8)>&7C%?4&<!7.':E99G:C*).%@@;A
@r2021
AGNNGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAANAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTA
+
**%+"($!#"&'!+$)$(*&#'(*'(+$!!()))*&&$"**(&!#!%(%"((+"%#$#+&!*+(%&+*&(!!&+%+)$')()!'*'+*("!#""!%!*'"#$#"%*#%"*"%(*'*#'%$'%+'!"&%$+!)!($+!(*+*#*+
@r2022
TNAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATC
+
.D<!6;3008=$"C$(F2,:A(?E(-+"0<,F)7DC2@,,&!#)
@r2023
ACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAANTCAATCCAT
+
2'5<.9B(-/@8@%(509".:-#'G>.BF/$1+,B(("!'H>8D:!7895+8*?'6A+<>/F0/@)39"FB80"4F03<3C::+7"
@r2024
NAGTGATGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCA
+
!$#!&"+''*#$&%*#%"*!'$+"%&"*&'*"#+!)'*('$"'#"$&%+$)+!#+#&&$'*$%&*%&$*"(!+&()#+%
@r2025
CAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATNGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGT
+
72.,+-"!0'<5.8E;7AH@#647)51"><C.E(=/9>1*0/';1?$#57C$%1,HED>D"#*72<(41%;=A$!!G<@.(:F=8H@,"D*0G=7F4)!54$C.%A0(H639@0143F%;:H!(9?:91.D+4$%AB2"$*G)4@&1:'1<>(""BD4,8@E224>-2(/
@r2026
ATAAATTGACGCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTACTGCGGATGGATATGCCACAGGGACATCGCCACCAGAAACGCNCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGC
+
!'%')&'*%+!&$#*&(%*$!)#)+#!'(#'%%'&*%*'%#!#&'!)#&$##'(*#(!'#%*!()"&&'#(!%"**!#*""$+!"(%($%"*"#*#+$$**+*!%!)$$("(!!'#(&*$&'#'##%!)%#")*&&+"$%!$**#)*'##*'$*))$##$'(("$!(
@r2027
GAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCA
+
4-/A0A#57F<#B#@)!85<?"@%'"/-%.'+3H%3(10:>790C#2>3
@r2028
TAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCANAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATNGCGAAATGCTTAATAAATGCTCGGAAGGTATG
+
5<9G%%<.5?E:>60%:;7+(#:BC7HH5FD;!@.%%&B4&EC6)4-:'"&B'E2>9'*!.#4/,;12"!96C)D,4*&B9!%92%C$'"/"90E;@84#48(H$.'=?%D8*C($)41'-E:74H,9H>-6-'>G"G?H-;6:@3@)"*<C!D<90*-AA:D@)>2A#=!F*F%%C=A7.C40--91@C>);8@.584(=9A#86F)=>)"5FCD5?/1;F,D9D1!4:2#D!'G,8H9D@+5?$<H<4C>G!H&%(#!F:+2G+@4(29E+7<?/:09(=H;91G.D1240F<=B3
@r2029
CGGCACTTTTTTCCGCTGCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTCCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCT
+
82$?'';A#?2##94;C7B->378&<&70:;62CD%),$C'+=$.'C'G1E3C!252E.<"?A15$%'B7!,5)8%C<#0.2*!H-?HH#/(&;#,5;.!,'<%><0$5H<?G?/>*<%E1,H"09D*G+4-?1ED1*6B4%>>
@r2030
CGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCTTCGCACTCGCGGGGATTTATTTTATCTGAACTCG
+
7)0=&!>289%+!!DB4?=+4DE?<>","5/8-/7/@?FH*1;B4.()G<,=&>495G-?F#?1&&:#6(A(<='GGE4F'."<@.1'#14G#D1;
@r2031
AAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCNCAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCAT
+
&./7#E2)8(D?E?F8-985D'H%/=:8*5"<C,$>----*"/!8;C0=EG4"*8)4,E.F1(*4E3B*G,831C@6D/1"7/,!E=7(1,5F!#"D"??*)>.'1,4,F-;&D>?>H$(/(<35"@C2EH,!=/-G).)2='()5+<'=E6E-@+B3+&F,'>A"B=''.*EAC6<(G1>6*/,49GC-BA:,*-%*#++?.>41$@;534(>,7>0"2?#?(%>F
@r2032
CCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTA
+
;-A?/-2$.%>D7&@6,@E4<>.:<9&E&F1:H@)>C4:+F)-4#%&=+,(A5B):,)(&!EA;<!<G'B.17/%=/6)A457F#+7*FC373"-E</<"%(6:8EE,C>+(6;;/@C@B*"73;!.G4+>2'F#;0+'6A<
@r2033
GGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGNTCTTCTTCGTCATAACTTAAT
+
$&+'%%&'"!'")*)(*##&(''))$%+$"*#+'$&+#&*%$"%$'#%()!$&$+$*)%#*"+)&#%("()*+)$!*%)'$
@r2034
TATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTNTATCT
+
G4+@,5(<20D3711:2F;9--*;3HF/$F1E.?H@3'(64A9=5"G>
@r2035
CTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAA
+
-HE-6+70-2(/A&$!;,2C=>:=4=/=9&3<"!4E!2<E*.)
@r2036
GAAGGTCGATGCGGCGACCAAATCGTTGTAAANCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGCGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCT
+
:'9A)5*?&B2:E8;H2:!)A&HD3C9G!3@631'H.3=B7G56B28:$0#4/1H1(1"@+/9BB'@6$F4>":.)*3@.D>7=/H"6.FE$51@07(D+#"8B>FA<G*CH,.*
@r2037
NNTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAA
+
#))H87C?H,(=(%)#>,%$$#.*G*(@;)#"2%/,'B1+=@!8D>)%'$)65&0F*G>,&A<C*A%7":<'=@A.-&HB!'77DHF><15?:51=,A#1""::D"4&H.D8/;&";F9>0+*@(/4A41E584E)*71&2!4:49*?-8<72D+CE(<C/==A>$(GD6.05:$&9D6/)%%.@@&"8E59!$E9@);(5D(69>5"#F&
@r2038
CGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAATTGACCTGCA
+
2C3G!:$;'G@-9&B':E:7C5!++'74-$414*'!*"%31%H:H/((G-.$2D.(>@8E2,);#44>6:4G9C
@r2039
GAGGCGCTCCGTTCCGCTGCTGTTTCAGATGAACTGGCATTCGTCTCG
+
B$B;423,<3E16"!5-3==B,3@.<*<FF),!%"%''1D01?@19%6
@r2040
CGGGGATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCA
+
>C'2E<!9.0H(2<@)<1HE1@%<7244484C459B3>4-$3E2<@&?2658B+';F&
@r2041
TCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTC
+
178&6G5B/)%>"*+&B?54!0A'1FA)-/-<(/6:2:*!!!"&3-99!3:+.#4?3G;E$=<7A6%D@,(B/H7-,?=-H<)6$6"(*A%82?G<)-
@r2042
CCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTT
+
>07@)@?:)E1*!!;24'HG/05.9%"F)4#=<&4;29$(/8E>D+G,0/%%F9/C0"F.0,D&#.1:B@C!GE#B4.CC$.DHFG8F
@r2043
ACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCT
+
:0!?4*8@"FGGG(C1.<.1@80!89)'43+(@6D1H/DB44"9HC5&F3'-(#-7@4
@r2044
CATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGC
+
%="518?E;%<830;;F+EA/DHD%72D9-8;="!@=6E9&-*F$<:9G-!E6#0#H66"*?4D!8EFB.AAG7'(+>?/*=-@"%E?,,@30%6.E
@r2045
CAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGA
+
E'-5BFBC/,19;.<=%5:B#B>(53<G$;2.>73;#9(-(+A@5."%6.:<>'2&@""H:9):4#@!8G'D-*"!$E8;
@r2046
GGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCAT
+
+G)!8'2B<.+42FCB?,3..AE)9:C=:$9:>$D4-!=6
@r2047
GAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCATCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTTCATTTACATAAACATTGCTGATACCGTTTAGCTGAAACGA
+
61%E@:+E+)$B=@E@<@<!2'!D66+F@'"8%71&./>A3)E:D,07(1H%59/#"60A#=*;'3#1+4&E2$,97&F:>1B(2(9%;5/)D,<8B5@A8:7=DF):!3=-E6(!C$F@..4"B;#2A(?>40+H?::C.<>"'0FEAH!F40A6@834E$B=A@A
@r2048
TATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGC
+
?%5,9#F()#+#:!"F$';9%;59+$E>!6@E',%1%2&/,0A@+C(2/::?<:.H-/</.B)!"6/:+2<6%9@+,.!89!1>=
@r2049
CTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGA
+
H@'5:82(0"/F!5:29CD!E#EA2$*FA%H=7<D)E''2&$@>2B'476$?3/!GCG+</"A;E4#7@<+<'
@r2050
CACTCTGTGGTGCTGCGGCCAGAATGCGGCGNGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACG
+
4D&&>>:("@::":6.:*7&C@7*@<?B"$*8H?"H?E/E?5GG28F!'A:#BD$>+(1D>),2)9=$/1F
@r2051
AAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAANGTGACGCATATATTCC
+
<$86$$"?B38B(*E387+5;@1'#+=#0510);4C!=$C.BFG#,GC/:9,G*"<<60;99%
@r2052
NAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGNCATATGGACAAGCTGATCTGCGGCTGGCGTAA
+
%)F1>>B->%=&G4C!$!;.6/#G&GB"41C:#DE?+0=>>*!)98F@9+FA/H%4DAH7*4=6->!*=EC?EHH64H)6=8"
@r2053
CTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTANGGAAGT
+
>B8),!0%E5/1C9H!;6<D9'F&F(7&(7(;#93A+&*@#;D(?C!09&?>,-G
@r2054
AGCNNCNACCAACAGCCCCGCCAATGGCGCTGCCGATACTNCCGACAATCCCCA
+
&')$$$+"+%**%"''!%&+(!%)#"#*#'!(+#(+(''!'!'&!#'&#(*'&&
@r2055
CTCAAATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCNCCACCNACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAG
+
@";5$,/3?>E=%F+5@;2C>++!?=+95F,>+1'>-H)"1+:-9&5@=71GD;C5'>:F&'4453.%H*6(=)?=4)D<6E@172$F)3.>52%268-E7>)<A4:<.9@"/DD/+:H"8<9@G1"#D3*>!2=!#5G+!'A0))2,8=>,=E+!0:C$5=/A:&.6-7&@;*D-5$<-:"C&DHC@$EB34&416+,-:(,'@-EH3D*!!"('%H$.F&+F>#.*D:A
@r2056
ATTTCTGCGATCATCGCCAGCGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATT
+
EF!%82,<#(B19D+#+(&%A:;D18+=":*!742E!D@+CA(:E=;-$@@C@&0D&>=:!)54D!C@@E0)/8<9AC$D"HD&$3/?,=;''D43*CD<?8+&GF@%6&B/5+A,?-,?!G).0$6160<:0&A?EC+-83#:
@r2057
GTTCAATATCATCAACAAAAGCAGCAAGTTCATCATAACCCGCCACNTCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAG
+
G+?H&&;,=,7G"7(349'B(B&2%?6##6)!/-(F@!<&<)8<@$,&*33"-<!$2E(:E&-=B)0/$A/C2'/5/:-$7%:2@A@9!#"(1&8=!),:G!$@6F+F$(&*."
@r2058
TGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTNATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAANTCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTA
+
/#=05(G.=22<=)D9'."%?64$.#8)?=&!(:71CD?-<-/*!;>A>C(G>+EF>0.);G*5&)11?</*=.;?:&,1/5,(EF3C8+4B>."813H0844A<>,+%!$=,&8$!:,0F='1:H?<<-.(F'1DA>.3,.956A7H<?'E+<-(6E0;$7C0B&9+&<D62H%=""/D+5,C56B.D#53!:!'*B02+@5@*;='6D+<?%C--77:.".)F4A<2:-'E<=)1D1%"EF>0E5-/,,@:0'.A5=,%4;A;>#D-/,GE#1$60%:($"-=4)BA:05#.!
@r2059
GCCTTACGCTGTGTGGTCAGGTACGCATNACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGNA
+
/=E.17.-#A%!,%'2%)+*5&C2;79D4.(<:6/>=%G/+*#5,GD3)E+:/5C>2.!>'3'G%1.@A+A8F:3(92H1.,.$24
@r2060
TAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCAGAAATT
+
=6?2E'(=G%'$'<6'&>$!&'H?B0(4B!(AE-%;0A8?8GCE'#
@r2061
ATTGNACGTGGTTTGATGGCCTCCACGCACGTAGCGNTATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGANAGGTTACCGGTGATTCTGTCCATTGGTT
+
)""!'+'+(&"&#&!'&)%%&$"!(#!"*+)"+!+'*%!!%+#&)'&)!"$$)!!"*+*'$&$$!%"(++'#&)'*$'##$!)#$!&'&(#&+)"'!"()'""+()**')'#)*&'
@r2062
NAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCNTCACCTCAATTTTNAGACATTAGCCTGCGGGNAAAAGATGAGG
+
+!))$!'+#%!%'''"$)!*+%#$*%$$(**&#)*''&+%(*#%%%&+'$+&)+")&(&!$+$'($)!%"!)('"**)(($#(%+$%)
@r2063
GNTNTAANAANTNACTCGAAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGA
+
'($&((&"!*##'!&#"((+(**%!$*)*#%"+%%&#)"&&%$!*'+$%+)!"#++*#'")
@r2064
GAATCANNACAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATNGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAANATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCG
+
*$%&"*$!(#+$$')#'(*"!)*(%"#&$+%%#")%"+"&%($)%#!*)*!(')')'%(&$"*#'*+'*%!$$("(+#%$&***(*$%)!(*+*$'#"+$!#"*("+)'%$$+&++)*!)*'+$((!"*$('%*%*$((("+#&**$")+$$&$'#+"'%"%'""'()!(!$('##+(+"'!*'+()+%)"$!!&%#*$#$%$!#$+)!(#*#"*%)*#$%""*"!(**
@r2065
ACCTGCCCCAGCACCTGTTTGAATCACNATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTATCAGGA
+
"2CF3+3.>)*G&1B-D-F/"%=;/)9@"3=>7'D:C#D$='6*61$')C.#,#"6*4."<2*-25E'&%=&=>:'7:,!-*>EC/86+F-#EG(99.FE2)&7<4A:G
@r2066
TCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACANGAACTGNAGTGCA
+
10C96>%(%60)0--)9)&&/#DE(57=7=%@!47-!A:=)5@257>H26A$)6+.1#D*!'
@r2067
ANNTCGTTTTNNAGGTNNNCTAATCGATTTGGCCATACTACTAANTCCTCAATAGCTTTAAGAAGGTTATGTTTAAAACNATCGCTTAATTTGTCACCGACATGGACTGNGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGANTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTAC
+
!'#((#)((%#$*%((%!+))()$"&$$'+*+($!"*!%#$$&"!!$!%!$(+&#+#&&'')!(#&+)%#**")!+)%!"%$($)%+$(")*)*((&+%""#(+)+*!%)#++%!(('#!!%"$#!!+$&$#*+%&'*&""("!&+$($%!)(*!"&'(#'#$'%*'$(""+%+')%#!(+*#+&!'!+%"++!)'+"(!!
@r2068
TCGCTGAGCANATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGN
+
;H;DD981-.#=;EE.023'G3.@98*;!;E@>*@,;0(?(6/G#F(1)H?9<%#+-<;@B&&HE?F?F7A;0
@r2069
GCGCCCACCAGAACACCTTGCCGANCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCAC
+
=9>+2=$$FC/,$E0AE?48.!"E!!>9-8=(F79<FC81&0687>&A>>5+$(2%6DHF+E3#E.@>#F55
@r2070
NNAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCAGAACAGTGTGTAACAGTCCGTCACACCGT
+
%'?!@5.97>>'.A%/C8/%-DD90$?D92G$6-A&0;,5;(84=*A93F-/-0H$((21.:2@#80#'5&BGC6(*;?'*8*C'9A<:
@r2071
TNCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATANCACCACAAAATGGACATTTTTCACC
+
'!+')'('!$$)%)!!"#'*!#+)#(++'+'!#++'%(#""'#'("#%+!)*#&%+&''($$('($!'$&$#"%***&'+**#(#**+%&&$))*'!&)+&)(*''%*(&&$&(&'&&"*"*$)**(
@r2072
AGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGNTTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGC
+
?:/==AH6:G/0;7F@,4%68*0:4'CC5A(4*8,31.-0?4C$?A.8&>>H,A?(+78("%15/D)@9@5!?1></;HD670H<;C0/-.7GH)?%<<%8D4--G?@4"0$%45*':+;90&.$,??2=;+5<F4%-
@r2073
TGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGNTCATGCCGGTTGC
+
(*%&$+"%+)('#+&"!!!#+$)''&#%%("&*#!#$'%$)"%%%+)*&('""*"#)!$%!*!%"+)!#*"!*)+'"*$!"'&)'!$#+#$)"##)%%''"$$$&!*"(%)+!#)+!(*!'+$"#(&!(+!$"%$$
@r2074
ANNTCCNTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCNTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTA
+
'$!+)(#"%+!!&'$%#%)%!!!(('&'(*)$+#&!%*++%+$$""'#)*!"&)*$"(%"'&++'%!%!#&*)(#+!+*#!")$*!)'"+!*'+(!%%!)'"!+&)$'%))))*''((#%$"+)(%+!!++&'!+)%"'#&&'%%!*%"(!$+*))(%#*#+'!!%)!%)%%+!')*($%!*+!'!*"'+#(+%&&!
@r2075
CCCTGNACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCA
+
D=;&7*C#BF>(D9H7BE>A'.;+GD"#99>$,+!5.C?2:7=05091$H#=CA3
@r2076
CTTCCNNCCGNANCNACCTTACTNNAATCGATGGTGTCTGCGGNGTGAAAGAACACCAACANGGGTGTTACCACTACCGCAGGNAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATNACC
+
)%'&$$!%&!)'#&"(*&)#'%$#+'*#!(#*("'(+*!'+$#'(''(+"'!+"!)&!'"$+)$%()+$*#)!)(%)(+""!'"+!&%&)#()$"#"'#!#'!((($+!'&&"()&%'&)!$(
@r2077
TATGCTCTCNTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCA
+
,$0-GC*"7:(<(&G6"<(06'3/H-@?D$4=8@BE&?A-><5;A18E'5
@r2078
GNCCGGGNGCACACNGTCNGNANGCTCTATNTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGT
+
)%(!#%*"!*)*'*"$%("#!#*&%()!*(%+')+%"(!)**+&)'""*($#!+$'*$*&+%#*'(##'&*$!(&!)&$%)&(*&*))#")'%"#%%+)'+*%*&+"'&!&
@r2079
GGCATGGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCG
+
6G./%$8(::)B6=D4%06;/+2='C#%!?%@'<C1$'55EE,E=-H;*C9D=5,@9(A7-8GA
@r2080
TTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATA
+
.??E-<&.D1DD=@/+D;('BF5+;&,85*G"$@8E;05$334F3:#(C3G$1>:+&D;?GD!4.'G6/*0E"!G:=!%>F.7"-(5(8E(B#:<)A1::$7CBB9*C''7.C*<2$C;0CE.5=DD*.DGCB)D:89HGGH+565@3)F1E<,'9%H5?0
@r2081
TCCAGCTTTTGTGAAAGGGNTGCGGCTAACGTATGAAATTCTTCGTCTT
+
#*++('+!*'$$##!)$!(*!"&)#&("$+&#'#)$#%*"#($')!'&(
@r2082
GNTGGNCGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGATANGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCNGGGTGGCNTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTGCGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCGAACACTTATGGCTATCCNGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGCTGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGACCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATC
+
!!'%)!#+!!"'"')$!$$+*$"*+"#*)'$**)+$&%$!"#!+#*!%()*'"(!!%%)+*$(#"%#*)"'(%'"&'$+)"%#"%%+#+!#$(##(&'!+#+#')*+&+#&!#)!#)$(!%(+##&&$$)#%!$'!!"**'(+'!#)%$'"'*#'#$+"#&()$'!+$(%"&''($*%"('$+%))*!#$*!+$#$%($$""(!")+#'!&#&#(!##"&**))!%$"&*#"###"$'%"*(!+"##')#"#)'+"($()&$#*()&%*'&!(&+"*!*%$$+"+!(!"&")*!)#%*$+"')**$!""%#"+'*&'%#!#%'#($$(*$++$')*!&"!#%+&")(&!*+*'*'#+#$$*#&**"$*#*"#"#!+%&&*+'#)%!'%*)#*$()#%++&$*"'$+')+!#$&(!'#)*%)!')*##"$**+*!)($%*)'$*(#)*%%%&$'$$'"#%!)()%+!!*'+#*%&
@r2083
GTCGAAGTGATATTTTTAGNCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATA
+
EE8DB:9-,),F&#!14-?$8<<=*@'*1./=';5F9@@7$/96<+H#7/!%;7F:?$.@FH9:<4#7=+8/++H45
@r2084
GCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCACACTTGCAATGGAACTGGCTGTTGTTACCGGG
+
7$,=%E44.CDA3=''H,CE106C6<:>7;9G/=53EC-E&D>=?'F2>D9=7$5);3"!!"5-1#%C'5D8(+@F:"#%=B8F8"H:).()$8D?#7++>0#45!'7E7!>1,2G,)*-@&%
@r2085
GCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCG
+
11<##*HDH=)>$C6;?7D@%5BD372,=6#6@=;C1C8DFD8"F$&/A6@BH1;<7AEAB7G;*
@r2086
GGGGCGACATTGTCATCATATGCAGGAACCATGANTGCAATCCTGCTTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCNGTACACCGAAGGTAAGGCGCAGACGGTCGATGTTTGCAGACGTAATGCTGCGGGTGATCGGCGTGT
+
+.-<D.99<0,*>5!:=@6H/48'4!+BFH/+C72=E5@,A:="A*'")C317?;"=/CBA).=&'(;:)1:A''0;:AC"%0>2.-1/<.EB9,G36#<-5:-8699HA+4GA*1(,)CH9F9$;1$7G:4@@G"%A86.."<9B.'6/'G>)=2HB)#'#2)
@r2087
AATNAGCCGCTGATGCTTGAACNCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCGANGAGGCA
+
11G.2@G.?*.>H>'D&EH#/,0C1,<);4G6*?<-*D3CD57<<&G4'B6)?G#<0"/638E9'#!'E:0;CF)6$$C2H=1-@*C"'%1:5'6$$1-6(B%81"$+7@*"E/F@)&E$A:3
@r2088
AAAGGAGCCTGTAGCTCCCTGATGATNTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTATGAATCCCATCAGCGTTACCGTTTCCCGGTGCTTCTTCAGTACGCNACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGNTTGTCATACCTGGTTTCTCTC
+
=8;.3902E.#.""60)C2E19B>$)-@:<1E8&E<+2:3>)9BD>5A:*?&++$1=E</!!%?A@>6<C198:7B3A5#;,>>2*&85/(@!()+:9G+-6%-6E!,5FF278;C:B1B"D!C98;/7$2,(%!2DF95*(2;:+>+H64>,,090:C472):*)0+(D)=@68E)1""'7!-*4AE8G"@1,##B(B?0)5?>'F';#G71F/D/H+3F!'=FD-AH.AF!3323.*!@%1&#G28*2C5%)7*4!%*7C26=@A<A#C@7B/?>?"!;@8@#4:C,)DA-'H&EH79*2B()2)7E94B'@/5F46$F>(.8&*':+,13E:H2&469(>7#EH7A
@r2089
TTNGCATGGAGACAAGACACCGGATCTGCACAACATTGAT
+
85?%C!=G7.?D7=3&:D<HD*-7@0>3&;*$/=.==2&1
@r2090
GCGGAAAGAGCATTATTCAGCGCCCGTTNCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTTGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTANGGNCCGCCACNACGATGAACAGACGCTGCTGCGTGTGGATGAGGCNATCANTAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCCTGTATCTGCTGGGATACTGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGG
+
$@46??#7=?/==(H/B#.E<?05*5D&%<%8&:>=.*G6H*9''4B1!83!/#0&'0D<(B95*;C)(GF>C+)*-8/1<":-.A--.EG)4(7H!;=5%*@-+:3<34H%B;H,%>$48'-2F+.H.;"!,<A&/E&'C(!"+GFA588-,,#C$A?>F*A)*B*5032:AB()"=84)F(.B0FE)5*%F2**<27H>$D(3&'F!D7-25(+0#'1&#5.%B)H9=>&7A>./.#?*@'2(.:);3E(1/+H#B5215-2?+-":<G9;GA)?")1F,%,G(74H-3;('3!11A-%-3?65A.9+)E1%E)/;CC5;&%"+A2==!'D8.5-"8+9-=!0=/?1/H#&B23=./7"581!$!,(BH?>7D+EA=B/2C26"+@#/!1F-$A
@r2091
AAAACAGGAAAGGGGGTTAGTGAATGCCTTTGCTTGATCTCAGTTTCAGTATTAATATCCA
+
+"%(!''**($#"!&+**&%%$"$!!+$+(#+')%%)$"$+%##)!#$($!)$)&&+('&$
@r2092
AGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACANTTCGTCGATGG
+
3>:3@**3=;"B6!8.*CE"B23H.F$;-?5D<3.14(9$9-!C7;A#%0D67B&),531AC+38GB;9@&E<B.+D%6GE9'B(5HF<1A.<3+826.F?"?!,#D+"G*E!:1@(H*FG0C25,A+H;A#((=<37"-'6G#0?."1*=$)F1-&#.$#E&&D6D*&/3@+,(-50##'E+&7@@C6."5/?-7,.3*!CD83D9*F'(@,!%!0,
@r2093
CCTCCNGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACNGTGTGTAACAGTCCGTCACNCCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTANGAATCGTCCCCCGGCAGACCAGCCACCACGGCAA
+
$(+!)'"!')&%$#)'('!"'!"$!()%*+#!(*%()%)&'%!#&!$)('*$#%"$!!%)+"+)+#""#(('*"%)#+'&#$&''&##"+)#(%**'$*)"#%$%*'!'%()**#'("*(('#'((!)*)!")&"!%$"""+$)*$$$+%!"""%(%)(''&()"#+)%&%
@r2094
ACCGCNCGCAAGGTATTCAAGNACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGC
+
$'*#!!*!*)*%&*+'#)!+&"!(#'%(*%'*+*+!"+!&)*)+"'%"$#+(!&&$#'&#%"$""$&'!'$*'$!"&&#)!*#(%))!&+!&%)!'+++!!'"+%)&$%#'$!!"**$(!!*+'**&"!%))&&((*$($$*%')
@r2095
CAACNNGCGGCAGGGCTTGCCGGAGGTGTCCGCNTTGGCCCGGTCGGGAATGAAGTTATCCCCGCTTCCGCGGATGTGGCGGACATGACGGCGGATGACGTAATGCNGATGACAGTATCAGAAGGGATCGCAGGAGAAGTCC
+
$$&&!%+(&*!"'(*!"'((()*&&'&+"!&*&!""(##$)$)(%'*)'$'#&##*&#&"++)"!&$+($(')##+#+&%$#*++#'"%$*!*$#"+))#%%*&#'+*%*"(&(+'#&()')!'&!**&&!+!%$$"$(&()
@r2096
TACGNCAATAGTCCGCATAAGCGAATTTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTNCCT
+
))%)&++%$!#(')$'#))(&#!#%$#%)$(""!"&'%%))%+($%+(*&$!+#$#$+''$$&"&
@r2097
TGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGCC
+
98*=?@E7#0&B+?D+12A&$@&:(:.46BF?2C<AEC$G/'@?,7<+@<7.6'11971/H<<H6."7,&ED0?;!)6<!&#1;CA'0?://G''+-:!8-)0,0@>/-9'414;!97
@r2098
ATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTG
+
;CF@$1!-4.>(1FDF/7H2+,599B8BGH&0/"AA94+;6
@r2099
ATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTANTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATT
+
<!>(">:-':)37>1E82(<;<-5'4C1(FC)'E335*/G%%+0%<3G)G*)#)"CC<F=-)+027'6!D/3?$()&5*$15<27/0,,39+'(#C1B#@1)H#7=>8,)+76'&'0:)$66?@5G&!@)4F'554<EF8@,5&%4=">"*E(&H5;"/6C:)@"*E+&%+A/G:CD/A$/&D::<!3%)=/,%@G/6=@@-2.50@F3&/*8@60#-@<"<<2.!:+*=:$!3;C.-!H/7<"FF4,#5'?
@r2100
CCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTNTTTGAGCAG
+
:''H6H-"99H/#0,0>178+&0*:E6:)=@74-#E#*2/(6+!'5AH4!22'0")8HA8*%2.!"
@r2101
TTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAA
+
7;#AA7?,):=5,C,$&.A1;31C27E8<12,"2B.(*6A$')8':HB,"0@D*("D,>+;7D%#9F43
@r2102
NTNNGNTGCAGNNNNGCATGTGGCGGGTGACGCGAAAAAATGCC
+
!'*'*$$&''$'!%%)+$$#&'"(+*))"**%#%!#""*#("%(
@r2103
GNCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGA
+
(&%')EAD8-<C%&2H"=!>#/#2.)*(B=81H*'G723:H(#C9E-("",F&-+'AG/"4C+-A'71#D10$@:",-21"74<"#EDE*F@A&)&.D9F'<($)C$=?H8D5<*3<)1.8-
@r2104
CTACATATCACAACGTGCCTGGAGGCCATCAAACCACGTCAAATAATNAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGNCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGG
+
+%#')*!))$"#&"$"&!!%%#((")'%&&$&%(!%!(#'()&*!)'))))$"#%++""&!'+)+&%*$)''$#$(+%%#)%&&'(*''"!#+%%&+%+%+(')#+)"%$%)(&*%")!$%#)(%$%*%!+$#!&*%%("$''&)'%*)+*%'!(#$&''!*$&++++&++'#*!!&!(#!&&$"&+'#&*((*(($*#+$)$!'&!&(&&)!&%*$+$&&"%&(!"&&$)#%*%)!)($!)$)&!"#'#*
@r2105
TATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGAT
+
,?3A?3$<(2036?H:?=(HDF;A?;*4?7;%,:'.@"+*H:@4/#A,8;(332/@G
@r2106
GCNCGTATTGCCGCCGCNTCTGCCGCACTTTTTCTCTGCGATGCNGATACCGCACTTCCCGCANCCTCTGTCGCATTCGTGGATGCCGTTGACGCACTCC
+
(*!+#(&'!&!&&&"'*!#+%()((#*)"+&"%($("!)("*"'!+%%#*#*#(*%*&(*%$*$#!$+)**#&*!')#&''$%*)!$%)(*&#$()"&*"
@r2107
AGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCG
+
>&5+;<1/;6;:$GEG>81G8)=(>BB.?F;HCC49*C=.8C%.A?6G<?#5*?,?<&E?.:$218-82&?-+7-!0BB;)62E&&@G/F)+@C@81#<$;00/8(958<:990A=D)9/F;;-$A)#:#2;BB'H5;<C<$.1H2B?$/-6DH,3&:9A>6,C"1)03+85<2C6/,/B8.EC
@r2108
TTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCNGGTCGCGGCGTTTGA
+
.<,B=?F%"B-318$>6$D9%H2DB2+G47"!$77"6A.!<F81$C*4=;C54(93#/'H/"&C3C06+"B&')2
@r2109
TACGTTTTCCATCTAAAAATTAGTAGTAGTNAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTT
+
G%747,"B".(BHG:%+$%>&E+!@2H+56+"4<%C#'4H0A"DHF>0%9F)3!!/G42D?<CD5"*2?"=$'?1#+8B<<"2A.
@r2110
GACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCNGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCTCAGGAGATGCTGATTAAGGCAGAGGCTGCNTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGAGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCG
+
.++E<?;G5C7!@>:9$5#B%=E,E1=#076G#D(9#0)6DD/3;D?/-CB884(>794/)&/548-!+=:,.*"AA$H9315-@A89<GBH34,())2D0'5G;9=E#H1%.G+/6<<2EH=(0A$018<<6**"@D@)+C;49.&F;.,$:)3//1$+%E%+B.8>%'!3(C@&G*#.;(-25"-9<:8@?F.>:)DD4*>3G0>50(%0=!!CGF!:%9HH*$2:BA7.FG=!7<@<C94,1330&A.*$BF"-6);99.#<;"%#/&E#,<9;8%!&BH#7;,39%2H-1D?C141@&8A':.G2@H=7..D+8G2>(1,2@!0D?)9-7:2!613=CA4,,.0@4@?(.;#,5.BG$B13!*G-DB#",8";;5-)4(+0*#@*':=>&6,A9***@;=:?-8B7#G0F8C.GB2A6/4G;$?7/4H=0:,B")3;&G29H%>7>!>;H&/""59@)7E50,/%>D62**
@r2111
ANNGATTTCGGGAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCAT
+
)'!*#"&*++"'!)+%")!+#)"!&$#%%+'%(&+%''!"&++('$%$!%'$*++!$%&$"%$')*"*($!!(&+)*&"'&"$%"""%&+)##$)!)('%%)(''+!!*$
@r2112
GGACTACAACNGNCNCACACCACCAAAGCTAACTGACAGGAGAA
+
07A0/:B:3,+#*H.E&"10?"?*3?C@62>9$+H.&AA/#;-C
@r2113
AATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTC
+
#92;9-3G@%>=/&@;(:,9,</*%/>CD/@/F%:-1!0,6"99BF1-E3B@D=?*:?(!-2<1#E(?=)DF7%+%>B'&#(83)CH#.=1!;6E';+;C-(
@r2114
CCCTGACGGGGAACTTCTCTGCAGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCC
+
44$B&,70?</>.#<>3D(8E+;#$%5D#3F==D=?4%$#-3?"".$-%44(">!<(9=4+0C;)-9H>;/14,-=C><2=E<(7,88)
@r2115
CGAAATTCAGCATTTTCACAAGCGTTATNTTTTANAAAACCGATCTCACTCTCCTTTGATGCGAA
+
;543*3B1:!6./=-H@)4?H2)21'=5$%)$::6?22:E=75C%+0(;'C3=?15,16<?7"+F
@r2116
GCTGAAAAATCCGAAACNGTCCAGCGTGAAGGTGTGTACGGGCGATCNTCAGGAAGACAGTG
+
*(%$('(&)%+'#'#+*"*$)+)!&$!!'&'*"(+(#'%"%)%$')%&##)$%(!+'!#%#+
@r2117
GCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGNGCGCGTTCAGATAGAGCCACTGAGGAGGGGAACCACCAAAGNCGANGTTATG
+
"+(+$"*+++!*%*%#+&(*($&!#)"&*&(&**'')$')%(!#'%&+)'*)"(#'#!'*(*!$%"&)&#+(+((**(&%!"+"#'#"&*$#!)$'+%+#!+(*))'"
@r2118
CGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATC
+
D,4")C&E?.+!!C;?2;"A7(..D48DG>."<'7!'>0)77&1G<=*F550$>%0@@:!!D8C(AC
@r2119
GNTNGGNANCNGGAGGTGATCATCCGCTGGCGCANTGAGCAGTGCAGCGAACTGAGCGCGCTGAGTGCCNCCTTNGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGAC
+
$$#))#$%)$"&%+&((**$&+))%((($(%*"#'$#!%%)*!+%&(((&!)$!(+$+(!$'*!*)$&"+*#$')'%%#)#)''#($)%'!#&$#)**&*('(+*!*%()#'#*(&%#!'*&+%!""%*)%+%%!!*)"!*+)"&'#%&%#%+!#%&+(&$'!$+
@r2120
CCGGTGACTCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAANTTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTNCCGCTGACAACGNCACCTGATACAGCCCCGTCGCCTCC
+
E*4%1?G?:=<82HB03=D.(+95(1C9BEB4G6BD'5;$<<$"D&!E2#(DD7!2/E&/<E16AA0">+!6*F=A%>1'4/*>5D?%3;1!8@-+CD-?"FB/)10/C7'5"A26-$<<1#<&B2<G26;&H?!C@ED6%DCD/-@./#C7*3F,8))8:@22;36@%9+8/9)G91G;<:>HC(#'33(/;%E6+$C<8+$'5%=!
@r2121
GGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACNGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGG
+
0+@'&4B.?-E;D,130G+/424--65)>!C28G4D.:54;"2/$.E*&4>8.FFE+&CAF+-4/)C/%<&,"'EG!:"%$#H2!B+H082:F)(8B"//H89G5>,*?9-.=+C:D8&*)"$9573;C
@r2122
TTTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAAT
+
!"/=/#?>5<8E507,4!EC2:?2.;,G?*0':1/13'%#C&;6E*/1?'775<A11$='...F228+;D%$>CGA40<;1"4$2#)0E&<98;<8?DH2.:5C%CB:<:=B7$&2C"7$G)@<H1B#2,#C;C@.7)-)G3H5-<:+AEB?',/"5%<7>85!G:0"5-8+;3(H21F"%>3+D6G:>0&FH;',/*0*;773C@5(4)7-@*4CF6
@r2123
TTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTGACGGATGTAGTCGCTTCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGNATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCC
+
@):/<2E2+>A4H*#D-!%8C$HF!035",,*+.2?+/162G8+(9%4A'F7&2F%+/:!!2)C"EG7?;<A*+/94F2>AA.)9'#3/F3-//&!=D9@E"11,$8B&6:0H=.A9B1#@,2=/99)&)(4$9@32>)A.E+)-5'>A;F'?
@r2124
TGGACCAAATAAAAACATCTCAGAATGGGGCATCCCTCAAAACGAGGGAAAACCCCCTAAAACGAGGGATAAAAC
+
F#D&;/:-?$0$8%0<#$=D2D(#0%$95>@616"%%G7(BA8&;/=@"EC/FB,"!&2>>6FG"#)26>(-8?A
@r2125
ATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTNGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTNTCGTATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGT
+
F&">$D!7*;H)>A/01*<->3G78?1$>=2DC3E@8B/$/*>4<47A$:$A=>><(7.3;6*-7E,<>GC/?@B,?F&9+3"!9(!<:"7&9E8"/3+)&A'D-.,)@0*?.=810$6HA26#:8+B3(97?9&/8$<8>.'9EA+!5B5,6&%73<'6$>''.;37':.(.B6+4H1#FE5G'>/8D3'1<?0B<#@%,4F98$:$%'<2'GF5&A@&;$351-GHA+>)E6(8%-)&G0+!!:87>-&?*43F9=4H;'.-C1%E2G+!B#DHA2%:DD/CG-+:=?1>8(
@r2126
NGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCT
+
*-G@::@>)D<*=HE&H!@+E*H28/F!?--,8.$@<<<&
@r2127
GCNNNCGGNCNTGAACGCGCAGATCACCGCAGCGGTTGCANCAGAAAACAGCCG
+
**#"!(*&#)"+(%'+#$#**)#+**())&#(*!!)+!!#(*)')$%!("&($$
@r2128
TNAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCAGATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTGTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACG
+
?86C(-+29?,AG(-:5.)3G24A-D))$?>$:+.=GB4.6)%$8@7+>&D/A%BB<)H<&7A18*3E?H336<H2.!AD9B#285"/,;.).9=A556&-?!247D+A3:)$;3AHE$F+A5$$?<7B(@'B=C,G/5814;%0F'!-:0CE6:<3A8CC,4D;=E'.C/*49A@E+2D<@A8'0?8$22
@r2129
TTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTG
+
4--5'H#)(B&-2&&!3(A"$/E$B"(8AA1D#,5%H)DA7A%2DD<$"7$5<?/@<<##,6A=,8HG2?%/5!B=6"3
@r2130
CTTTCTGTNCTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAG
+
CF($D+3#4@+,5E+&,$>2,9,8*H%4G-<33;C!+,G461E>80%D'A$E;"=>+,EC*F3/C(F>D'/";2B'*A<4$8G4+/&3'=81:=3D+66@A8*47@!@B16!"0=@FD44D*/
@r2131
GATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCC
+
7#1)4D;7398C1,=CB&>B>"H@(&BAG/4$)G*$A*G</#B@).'(?EE<E@G
@r2132
GCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGA
+
(1-(@F/BE)/0;4-H$.D6F@0/1@9=B%+.3A0$F)GF+.#,62%,D(#-7B/*-&<G(1?7E+>?$-=%.A?$;*F-E-
@r2133
TTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAACCCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGA
+
+3$!&+#5=,,9DE8>A4F">*:&:.36G?9B4@A.8:'1H&@6AC++2C"H=);,:(4*$B6GG744)98"GH+"9H#7;)8064102@)A'E1#7
@r2134
CCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGC
+
'FB'/;CA6%G57B@D2&B!!"743!@24CD'+(;$=:3B#3<A:9
@r2135
CGGGTGTTGCTGAACCGTGATTATACATCAACTGCANCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAA
+
)@)#46<?*A4-%;G?7*2)6:(-"1/@#=9A:FB:+:@=:.@C#/)G/+C/"G0E=H!<!:,D84"/(1C//16(*%'6@!EAA,';?7C4#+D05%
@r2136
AAATCCCTCCGNCGGAGNCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGG
+
?/!E$D5;-&E8/!.-.+44'60=.B$@,79'""<D=&7%%0AGH%7;>=,(/#0>"H*(4)%+:'G.
@r2137
TGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTNTNTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCT
+
4063635*$(#="6&74!C!%7?3>&,B=+$+7B3E;@()?2>D#*<??>DF=H@<0,:@+:D54?->&7G16+-/GFD57+7>AF'/$A176<$"32$D,59*0AD/%HE):?E;=68/!1#B8-D+E$55'2;8*+B@C1@96;$,4;2/<0,>,0#H=2=1)&$G")F!9*:+*(1)
@r2138
GAGTCAGTTCAGTCAGGGTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTC
+
3:%#?'3455@:43G9$HG?H,-8$@;.0BAE7C6/;:@-HG&/3,??5<9!9C=1@D4#@EGA1@FD9),!2(C'*21/;0"+H?9H?+.'"%'A+H(.H
@r2139
GTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGA
+
G'.E3D7D3=1*:4*<;7*H"(7%$()'>1-4%#%*:+(GB!034(/2>=/FHA@2!"6%B38,#30<@G&F!G*=,0$
@r2140
ATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCG
+
C726C8*#HD8EDCH(?13+$#5!@+@>=1$E=.#%0=/1
@r2141
CGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAG
+
F09G5'*?9BG5<4F#':*8(.A&:*/)+AA%,<29),"=346+G.4
@r2142
TCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCACCGGCGTCGCGGCACTACGGCAATAATCGGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGNCTTAGTATTTCCTTCAAGCTTTGCCACATCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATA
+
*+*&'!$"((#!)%'(*++"(!#*&#+$)+!&""+)())%"$&+')%)+!$*(*&%%)+"%%(*%+!)!&!*!+!$%"$(""+)+'%)*$*!$%+'&*$(%+)(%)'%"*)#(""$(%#$$*'#"!**%((%%(#''+!$)!#%*!"##!+$%+$&&#%'(%)&'+#*+(&#&&&"+&*))+)&"()!+(+*%"&($*%*$+"('!**$*"(%&(+(!
@r2143
CNCAATGCTTGGAACTGAGAAGACAGCGGATGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGNCGAC
+
'&'+#&(%*"+'"+&!#+"!$*(*+)("&#'%)**!'%!!()+!'*"'%$$!)(%&$'+*%+'(%++++(!#"*%'!#*&)!%$)(++("#!)&&&#%$+%$&%#'!$&)))&!&#"&+)%#$!&"#+%"(!$
@r2144
GANCNCCGCCCAGCAACAGCACAACCCNAACTGAGCCGTAGCCACTG
+
(%!)%(*%"+++%'"+!)$*)$&%%)%()$'+!'$)")'%)!'"+(&
@r2145
TGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAT
+
A5#$<=<3(#F,AE<?@$:#86)9E;2,)A&7DB"E&55FH*E+2@3<4E:@"(
@r2146
ACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCNGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGCGGTGAATGTGGTG
+
$>)-8;A5'-!>::751?B47D:5F$2!5A#/C)@H:$+(>-:8!7H+A0@H24",</,.43876>F.,?%8E8GH<:)$32&E!1;#FCB2)G6G3-259EG04:"*BD/-+;.9#);,@9BHC:;"G?4DA:07C-F>43<ECF@
@r2147
GGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTAGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCNTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAAT
+
>(F+ED;#0$)CD15';.9A;);D,E.D$.F(:,F",-*6,66D.BHB:"<BDD6,'+HFD>91&EFE;=30%@#:,:3A=#C1F'@D=0*0"0=D:''6%'=@F/<CBB'7C-,9*/,D2HH;D1$'G6D7AD'=/.;1,"E:*1A&%
@r2148
TTTGGCCTCAAATGGNCGCCGGATGACCCCTCCAGCGTGTTTTATC
+
++3<;H:67EE67>+6*1%A*=@&05@A@CBA/=GH)+62/?'&*B
@r2149
TGANTGACCAAACTCGAAGTTACGAANANGAAAGCGTCGAGCGAGCTTTAAC
+
($)'"**(%+(%"()!""#'!%"""')#(($)%"))#*'%!'$'$*)+)"'#
@r2150
CTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCANATATGCATCCTTGTT
+
74%0?D06A;=5.#=%(E**'5"7@5E$0:6&56,6/'E>G"9+6G/1"'F90
@r2151
CCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGT
+
)=;..$(+85C$A@!>A?$-FD+>DD@@%',F3"?#(%72/+9?<3&"D1+C9H+".*F::(GDHG8#/6#C>D0#/<HH@G!)7,?4/48!*11;/7'C(B?-&#
@r2152
TATGCTGCGCTNGCTGGCATCCTTGAATAGCCGACGCCNTTGCATCTTCCGCACTCTTTCTCG
+
4?6/7&3:6&-.>.);5('GF$H6C&!F+;5!BC3"!;@3/9>8+<A.46:;H=CE0;4:-5D
@r2153
TATTNCTGCANGAGTTACCCNTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTA
+
!*(&#)*'$#!+()*)#""')"****+*"&*(###+$(##(*+)'%!*!+#*!()(!#)*&+%'*')%
@r2154
TTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCA
+
.08?%5!3,/F&)!A6/%2)5H"!@@C9<340G&CH9(8!#%?6?01!)("042=?4.?E
@r2155
CNNCATCTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGT
+
##!=E9@A?7>4!0#%C5%4!CD+0.@9-)C,"3H.B'E,,!#H)6$)D''8F5-9BC51(8(F/F6F-.22C.1B1?"#2:06<,%?09=;2.+0((;G>.4-!*;*C#/(:&)1"(>9=DA$A9=+7D9*.:H73=H!="5&0B/5=)FE?'2,1">904G4':%.#E!-H3ACB6#-1H*E>/B>00DA&--7%EA1E')<"@73H
@r2156
GTTAAACAGATTGAGCAGGAAGTGCTTACCCCCTGGCCCACGGAG
+
E?BD+G",@H=;.4=#@;(C7*1=<A0$*&231,9$?-$G;7:*(
@r2157
NCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTC
+
#.-<C;/G'(+4"C8(5@6A:E58:(3@#9,94H908!8CHD%*?E2;A;H>#7948:&EDB3DA#!"(>57D!*')8AE7
@r2158
ATTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGAGTNTTTTGTGTCCCCCTGTTTTGAGGGATAGCAANCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGANGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATACCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTACGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGAATATGCATTTCATCGGCCGAACAACGGTGA
+
'=,G*3&(544<H&:3E/)$C5-):?G'$/1$"4&%#30<21$@"02FF68E)4@.6:6#,G?!(:#33%$!B-A+A0@?AB2178B,2E0D8;*5:<2@40<9>,E30;%$<*A2D<F?F,%=H9-E=B38"C(@2<C/#++!"B@&BFH3H>4/8-*0*(;-"&?(852'#-A.DC-28=%<4BC49/:<#&/8&+'&=19=@3D$<,.%6$,(F0A1H#8A19,#2955C3E&&0GA.-'1"$D6&9(794,@??%*4)<1;68%2%&7G8$3B.D<>:<@!=",2%'!,08%1,..-7/A4.3EF6))H4@-<.@79/E(B::'9$AG.D%C,'?4>/9:*4F)G%*#.BC=6'&=9*9<8E$17B*FB&:1@$1G1H&.=&&>F2">;+%+>4/47:=9$H*$.%1/!+2@&B-<;25>$5A5/F62F;99&?7&B1;03#37E+(B4ED*B>6;=,,89E0:7.$@
@r2159
AGCTGGGTAATGCGCGGGTTGTCNTTTCGCGCCGCAGGCGTCGNAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCG
+
,7,+@+21(B%*H6B)C6B1+<C9,!@()(+AEF"#H?',;+FBH>?..&<4GG$=,%(A<-8;3!+G9/=G')HBB>+
@r2160
ATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACC
+
/@/+HC9"../",!2/.4-:&;1*:<H+:G#"5/D8A*%EB-.)4:%<3
@r2161
CCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTNCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCC
+
2&60.;:16%C??><H0%2;C4B0/H8#(G?!@+3E<)6!=F69"?B"?6BD1;)*0*@9;3=7'5C>-%A@90,F/,:$?7-A!!957H6D
@r2162
GTCTATCGGATTTAGTGCGCTTTCTACNCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGG
+
8<0&?.>B4B"5-?&3!=D7&+"*<GC!#:6>14$$/>AD4&*&B2!9!&<B6;9(6"=C)/:
@r2163
CTGCACCNTTCCGGCGGGNATAGGTTTTATTGATGGCCTCATCCACACG
+
#*&+!("#$"%'$!)('"!!&*'%&'*(%!#"&%#)'(#!*!$%%'$#%
@r2164
GCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTC
+
62-"A&>E3(,C!A,#1%+G:6EB1C11&$-BG"G/'"??*'5&B:">")D-F&957@:1;E*,.4!3)/"$%?-2'!4E!A/?6'>8,.B@72#GB91:#0H!?=25):#0=)#!6(3D6>37BH&*<;!>2CE)7?-&ADB5+0GG":G-<0G3
@r2165
ATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAATACNCCGTTCGCCAGACCTNACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTA
+
HD)42+,"H&2;"&!4/-7B=<6,:B)AG3!B-.?H;4>+36<2HEA=F=<-++C,,59'F'7?#AABF,1=:>1))1,G2ECG#'077%!"9!:$
@r2166
TTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCG
+
B<:HH=&,5;;"(E4,-?32=8D,;'G0)+<@4:C8,4?"=G4%9,@B$17E767GG)7!!*1;=6A2/%':,7(E@2
@r2167
TAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCNTCGTTGAGTCNAATTTACCCAATTTTATTCAATAAGTCAATANCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGG
+
>-90:.5,<4=1:(E?,9)E%06A>6:<22#C2H%==1@-B/$*%>-)&7&@'HH=3DF/)(703<27G,;.6<"22D;1,+9648#"@F0E?55:3*06@@?'G4(%>D,&G09@5FHA6C)"@/*FE?+?<&F(D1!<CCC-02;;HE"0E2(0<%6'+5H#>-1?:&-*/;5$>+EG?;751FF<9&.D%$C,GE+,36F7,5;*!B*?*1*&.+B7)<+'1$81?*H@G"-=/#A25G<'
@r2168
GGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCNAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAATACAGTGCTCATGCTGCCCTGCT
+
96'E:EG156C(,,:;F'#E9#A(18#'7>*62.6.)*<+B37.:'H.%D!)..(6#)*H7@91;7D,?.+>8,098E+$5$=4C8.G>8,)B&D%$E2>))903B-">://+9AEF"9D92!5#$C<"9+/)835@9/$83
@r2169
GTNTGTATGTCGCCAAATTTAAAATACTGCTCCTCCCCGCAATGCGGGCTGGCAAC
+
$*"$("#!''#)"'(%*+*(*)+"##$+!*(+"*!""'#$)%!""+&*&&#*##*'
@r2170
CNGAACGGNCGNNCGGAGTAAGGNNTNCGNACGNCCCCTNGATGCGGTGAACTTCGTCAACGGAA
+
$!#)'$&'!!'$!&#($#*#('&"'%$"&"%(##&!"$'+*+'!!%&$+$$*#!%#$(#"(")(&
@r2171
GCACGCCAGNGACGNCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGT
+
+")$+&&*(#(&"!)'''&#)+!")&)%&$$%'+$#)($&'"#'&#)%('**(#+#*#%'!%'&"*""'%%%%%#++
@r2172
NATTNNGTNGCNTNACCGCCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCGCN
+
"))($!)!$"((")))%!#+&'($)$!'"#!+"!"*%$)'*)))!$+#%#)##)("'!&
@r2173
ATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGNGCCACGACCGTGACCAGTTCAGACGTATCCA
+
E=;H2*'8E+;3F0>&*@?2CBC?/8C2-0#C/5D:AB&6))5F%*2<=)F0"7A'3-&)0FEH6&?A3!(+C!
@r2174
GTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGAGGCCAGCGCCAGCAGCNACGNAATATCACGGATAGTCGGCTCAACGTGNGTTTT
+
;04=$C4F0207B$E40/*F;,8"*#63F::C9!#&%8.(C%&*4E@3693:@;>,$HB@5G&=+>1(??50,$D?6<)%F,#:1"E-97@1
@r2175
GCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATT
+
>A+78;84.5-.7;3:0'@9G'A%6A)/(G*-%A2!#;$@?E-4+("(E81>9CGBH*-!AC-&B6;>BG!
@r2176
ACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTNCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTNCGGCAAATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGCCTGCGG
+
@#>3>1"3!<<4*=D-5+((165D189*>"04-&'(?>C"9D)+-/.A-92%<::A<$2E1&%9/'%.&;>@0)&3-&3,<8;='C!*:)4#/.,,'4E?06G$EGE&;04!D/D3&$?57?98%>#=@?%#&D<0)F4$9:'+%E//C.$0+;.7<&135-/8D*515/(6<2/<%<5<9!$$:5GBE!3E)%FD+@F'+'7C9'@=C&14-!GDD"?;F&@$#(B33)B#%@:(='A%EC.2C/E/#1#:!-6>$5.E*.C>1A+C$=&6;7H=%#D-!(3C5B,=C)90,H:F?DH+H3@"
@r2177
GGCACGGCAGTTCCGGCTGTCGCCNGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTG
+
%$'+%$*!+++*"#%)*'')#')#%($(%%%&"!'("(*(!%**+$$($+)*""&%!&$+%+()$#''"+'!&$(#'#*&(+)'!!"&"'""))&+!
@r2178
TAATTTACTATATGGTTTCTGATAANAATCATTGCAAAGATCAAACAACTTGTATTACNTTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTCTGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGC
+
B,?:*0;BA<?5;H*H?E#8245&<4/&;>;$@>47$%3F!?7/"0B>@78E6@:?;=<1+GCECH>6@6&0#(,%-6-4,?(<F>=-5H:>%+>;BC&#=)=9AE.73D$*GE!/533/>(%6A0DC5F&HD+-D*534?<1;;56$)31')>D"58BH7/>B@+/:2.H&/+F*B!*H'5B!<DC:*%/=A<5:?=2>4GD5:3F,#=>1<!7-HA754HF(F0$-A$'
@r2179
TGTNGCCGCNTTCCGGCACGCTGGTCAGCCGGACNCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACG
+
(&"%)%)%)"#+%%!#*+%"'!**")!!$*&#*"$%)%%))"'+&&$")%&#!#$"*'(%!*!(!+$&!)%")$)
@r2180
GAATCACTGGCTTTTTTGGTTGTGCTTACCCATCNCTCCGCATCACCT
+
3'%E"%EC/%GG=1<8%B)6,"BD5F!1'!96E++//5F;7!F)&C2$
@r2181
ATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGG
+
%6!*@1':E61-?,'D5)D$"'"@%.4645$):C&1@G67BD5;#?6'E!?1,(;D,@!
@r2182
CTNNNATGCGGATTCTTTCNGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGC
+
&%%!#%+*()!()**$&$!&*'())$'&"##!$#+#+!%(!##)&%(%!)+*%('#
@r2183
TCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGNCCGACGGCCTCCACNAATGCCGATTTGCCACCGGTGTTCACACTGCGGATA
+
)@,.(6*=-DH.?<A+)'$591!9>@&%'=1%%3+D.:D#B=3:86;'3/*A(8$4+2<?@-1:".!!4,E"7(<<8/4>/!CH9(@"7$='6>-,,>#B'75%8:;/G4)-&7H/3.F%1(#%DC?)5H@E@=GD>$-3<F'0&#"4GC=.++;F)?:8+*C(G+33,?C=C$79$%C@.:3/+$-DF;5@!G
@r2184
GGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTNGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCCAGATAACGCGTGCTGGTTTCAA
+
8A/.,/BHB(>555F2BG+*B%=B'A%=8#"1A.3':/.1.7"E(*A1/>G+)E.$@#%6'73A(69F4AF33/@BE/A#;0!$,!;!0H!4@B?)82%F!'#'9+D4(>,4%$7$C-#"D"#E?7*+47!B9.'0@#AD=,ECA?F>A@E)D@=)),B%:$BDC"H#
@r2185
TGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGNTTGCCGCTGTTACCGTGCTGCGATCTT
+
:8.10=&&D#2'/&*C;>H0F%*0'A;!79A(C9:6B1C!>9&0!HD8+,=<;?1)((3E$#5)8:=@!5!3*
@r2186
TGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGANCCCGCCTATGCNCGGGTTTTCTTTTGTGCGCTTNCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGAT
+
@!1"0'-0F>H?#@.**,'6(!2"#B6%;17".F/>349C>%045<<)$4C0"GF)H8B/0'1?0-7-?&7(%@E>*!F<2>+.9029F&.H&#&&75#'!9+C#7B#-2(,E!1H9.9E"5HBF6"-(@.'B",*4=7"#-8$*9?8+C(152'9:>/A%&HF-;9$8<.#?.0*248?"71-,C9"
@r2187
GAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAA
+
-)%DC1;8.%'90/F21,'##D'<%:-5F@E>--+(884:/'C:,-E;;B<1"/EAE'+6C)
@r2188
ACGCACNTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAA
+
GH#"H4(2B2?H'F@0-"07(E>BH,8<;4=,##9!!D5);94!C/:,'=?@*'8(,<@=<!-)A/693AD47?9*'1(#%F*08!:F7"2(5E,D047.@E3C""27%4"B;:+$)'C@"G>(0:AH4>H49F?9<0#=2,G.@$7D>/
@r2189
AAAGAAATTCTGGCTAAAGCACTTGCCCATAAAGCAGATGTACTTCCGTT
+
966(?"A;FH!AF"<?;/6)-D*F>HH5%7B/5@#)63BF$=3F;!'"7B
@r2190
GCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGATAGTTATTGTCTCTGCC
+
=6,G;37>A<=;7,;+!'@E9#6=A=-4,.".A2:9*E95.*(D#:5@@!G<9;6%"ED28
@r2191
GCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTC
+
'*0EC;($"?2*,><':*8C1=+A9<GC@6C+7G6E37=+D:*2C?-4>"*!A4=<8,>=F8)CB9-&6H4<2$C(74>9:7E@9!
@r2192
ATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCAAGATTATCGACTCA
+
D&:!3*"/98&&47(F5B0@D9>9D5C3?!!%)"(,-6!<:A0(""F906=D!$HC0,5(?!*F5GF=E:C3!;B(H,#=.*H!A9(.5:?2
@r2193
ACGACCAGAGCGNTTTGTTCTGCAGCTGGTCTGTGGTGCT
+
0'D0D=/2!$=$@*79E;.,7+8FC0!@34H+3&"):'2E
@r2194
CTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCATACCTCTGATTTTGCTGCGCGAG
+
C@.F/5<*5)G20D2(-1+3=:'C&9*D0(0&!;/.FC1A'9%)@3<'7!=3$>$+4++-3@"::D*5$A-!8:&@9$7?;<,-B?&=D,C"BG:*1
@r2195
CGGCCTCTGACGCTTTCGTGGCCGCGGTAGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGC
+
B@,1B9";5<<D8<C;';/)"/@:'1+C243@G/'-@3'CEE"/%!7F$&E?GH.-:A#9/:+5G1B9D"FF&+-#5>>4+&7?%F5@"&?A3%$B5G#1%>3:+*F3+71*+B>"<0828A6;?%%+)H,A9D:'
@r2196
GCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGG
+
B5+#?!#,BF4'E39#+#8738'!F1"?%6;.A3,+=;,2<>;@B6'65>1+D>D?'!$*4#(>!;&EG*<+@CC
@r2197
CGATGATGGTTACGCCAGACTATCACATATGGTGCNTGAGGCTTATTCGGGCGCAGATCTGACCANGCG
+
):HG&?%3=*@"!BF+A4A+5&8=/'!?2!+1<2+(1F*5/?12$9%"C$A"(0F-70@.$A8/4H$4,
@r2198
NGTNCNATTTNTACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCA
+
##!)%'#)*("*!')%%+""!!*!)'$(*"!&(($($"'(%!+)&*"$&"&&"
@r2199
ACCTATANCCGCCGGAATGGTGCAGGAATGTCGATATCCTATCCCGTATCTGCTGAGATACTGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGT
+
,C,#0-F,DC<18>$31(6/24F34@3+9''@31?2'D8A519#@@+GA?3;:;>.;?74H86-!*$<5E"8%CD-#DHA;.@<AC42C+1%'A-$F((#DH7B.2?H;%(-6,E<6B>&&
@r2200
GGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGNATG
+
2G0A5+--)?0AC'(,D:A27#ECA8CAG2C@'2C!H/4=/
@r2201
ACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTC
+
',+7CD00<A5!<)6@#?"%AG1)+7,')4%,%B9/5-,5:(A1:7C$</H<E%9&96D3$(75//'*=,68/
@r2202
NCCCACACCNAGCATGCATACCNTTCCGCNATANCTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGNTAACACTTATGAA
+
'+#(!('))+#$#)$*#""($%#)+)+$*"#"#+!")*"&%"%!*###*&)+'($)&""$+"*+$&#&**!&"!%)""#"%$'+
@r2203
GGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCC
+
H--E6>A#1C$73>C#C&@5?(,??"F2D"B*A2B@4B'6/">"81'%,98*8E"
@r2204
NGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATAT
+
#B?"'=):=C$(>:,@=#$H40<$1A<0&!8;/"'@%;F@H?H+&9288,E#24:*%8*;$('%A!;-=<&GG>F(&>
@r2205
CAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATTAGCAATGTTTATGTAAA
+
*G-3!"*+<1?-15:B;/D@/"#5E$"=-553%-0&(54='@/#6%7:*DB$)&>7D3:5<71:>@26:D8+:)99&2"7@A"6A!CA9"12G>HA"9G+*="8'(D2>-317;+
@r2206
CAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCTATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTG
+
(1G.A:%25;@'$&B4++F"B88*)4<D&EB*5.1;'19;8(H"==6.7)5D$>?'H19)&7*46$275?$@13':+(F,A/<)5B''8B;1G62<>&;-,0)4?/39>=?0F8#;95@-<-G8";>D;CAE:"%0A%>5-/#(H@%H=?--'
@r2207
TATTACNATTTACTGAGAGCATTCNGAACACTACACAAATCTTTCCACGCTAAATCATAACGACCGGTTTCTTCCGTGTCAGNACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTGCCGCAGAGAAGTTCCCCGTCAGNGCTGTGGACATAGT
+
%6)C=E8:8?<AG9.0$(F717A!'!'266A;+!B@";"*G*!,GA9+8B,15>%=:#$?&!,D!:=7'2.(/">/6853-/BBF@)<H':8HBA2<*HH"G?F(0<C/($266267E@E7;*D71B5CC2<,//!88.!=CD(,95-&"<.08;<)085=6((>'"'7$0F95:2=;#2(4-1'&-,C=:)9C$'
@r2208
GCTNTGTTACAGGTCACTAATACCATCTAAGTAGTTGNTTCATAGTGACTGCATATGTTGTGTTTTACAGTATNATGTAGTCTGTTTTTTNTGCAAAATCTAATTTAGTATATT
+
#&(#*()+(*'+!!&&"+%)+&"&!!!!"$'((&('!$#&'(#&"&$)%%&!$###&((&%)(&#"$!'(#$*$%$&#"%&')%!)#'+&*)$*%)#)&"*(%(#(("$*%&#(
@r2209
TGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGCCCTGTCACGATTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCAATATCCACCCCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTCAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTNGTCACGCANGTTCTGCATGATGATGCGACGNCGGCGGTAAGCCGGGTCCGCCAGATTCT
+
:68#=5$(>DA@17%#25@H+32,):7@DD'84B@#17$.G1.A>2,;/$3?C8@(==*<;DH*+H7?)D!(?"4&??A'%5C!1E;(";,/0;D8)94.*10)A+H;.%$,=+AA7$23+1%=9@@=%2>#AH9G.F,23:B&#G#F9+2D1AB/F6-/BE8<$&8;F7>46@"6&$F#GH@F$D,4E:A(;>--2HD)%B1>$@"8C=@B/>."55C&"E,D*72#EB/7C0,&A0:!.""D:'!"48(-G;&?=:8,-=4;,B,%1(4@;;%8,>$B>?;"DGH:%A8*)B?::
@r2210
GAGAGGTCTGGAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAAGGGTTNCGGGATTTTTTATATCTGCACAACAGGTAAGAGNATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCT
+
++%)()&*"(&)*%%*)+$&%$#')!*%'&"!!&'**$#%(#+!'!)!$$+*+$!))"!)&%!")''"+++$(&++&++*&#"!#+'%%!!+)!'(!#++*("#+&'((''"+*$#$#!%(!"*++$#'!((*$''$%!+#""*'&"#
@r2211
GATAGTGAATTTAGTCTGGNTAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACG
+
%:"4>!"=012EH+&AG7F.?#"$56C435-6"0#96'$*C8.?<H=A'37=B<58(7-D3*.)3&&@@<E*@%1=0*6.(>1AG5*>A6.>:C>4"62&##"'+?
@r2212
GCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGNGTACAGGCACTGGTGGAAACCACCTNAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATNTCTATGNGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAAC
+
7)8.$@#1>GG2(6!?68/=:<*#H)G20,F9=EHA*!1+"61#-25)HG)/<A:$,7.%.1A>EE"@)9EE%34??(&.+#:<E9695>7*H%2;.35<*-B5,->7@2+<*+9<D,FB(:%2-7@?;37"H7)*:37*9.A*G/@*EC9!"@>H8?>.9;?E/&?=C15-6"(<.25'7<@%;2<AFB6('A!G>9+8"24>H,9A>BA<!150(3&:GA+6/'"$6F)3,29E;$<96E)><D/G*<273:7A"F6#'E
@r2213
TAGCAGNTNCACCGCTACGNAATGCNCGTATGGGGATGGGG
+
"%&())"$%*+$#!!!)!'%(+&!!+$(+)(%(+)'()")!
@r2214
ACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCANTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGG
+
"BG+>2!6+2,H3D,A&++"*F/@40C5:'5(7*040(G%A/?"6!01(1$"A4-&$5&$A4'D,2>/@!&EH>H7''6A;&1$B7&837*<830=;B8'4(;@C#7&<G.GG/78?,!$2=A&<=#(DGD1*$,=;8'
@r2215
ACGGCTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGCGNACATGGTACAGCNAGCCTGGCGAACGCG
+
!"+(*)&)+'*)!%+'&#%)#)+#'#"$$'&"$'+"**$(&'%+"*'#()%'+&%$#&!(&$%()'"!(&!"%+!+&)+*&***&'(#'&"
@r2216
NCTGCGATGCTGATACCGTACTTCCCGCAGCCTCTGTCGCCTTNGTGGATGCCGTTGACGCACACCCCGCCGCCGCTGTTT
+
*'8C$G,E5:B56$4#B:%#)@:BCH5-FH22)?9%*'-:+0-2E%*!2>4?.?1?,B4!:#F9F*5&:6,3.1.;:5A;G
@r2217
CATANCGGNGACCGNNGTCNCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCAAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGNTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAAT
+
(!)%#%$&")'!"%"$(%'!*%(+&$+%)&)&($(+#(")+!&!$#')&(&**%*)#!!#""(+"$*!($$%*)'$)!&(#(&''!!#!"+#&$*#"(&('*&$$('!)*(($%$*!#'#$+'#("$#('*$!++!$##*&'%%!#!%)&%+')')'"++("!(+!"#&#'$*!"&%)&''&(*+#)#((%***"$%*'"
@r2218
TGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGGCGTTCCTG
+
C/#3$7$,=H'+08.?6<,'*3D+?4"<C!=*#(.42%1<$$H#81A>().!(A:=2<&5$<@-39<)4#")H&-A'D;0<E2D>HE:G$BF*A;A$&0A4.#8B<G!)0G24&;*!<)+
@r2219
GNNCGATTTGGTCGGAGGCGGTTATCTTCTTTGCATTCACCGCA
+
$$*!$+#"##***)!*%)"&*%&'"+$&!&$(!*)&%*()#"&%
@r2220
CCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCT
+
=D0G9&?(#&619%-G)=<1$:"H1!F2G$9!)C=AD9,GCAA,0G#9-(=?/=1.262#FC*+93B25%9*"//;.";?H<G@7!BD>BB4=(@%):1'%!!H5%4D)F/@;'A+7H93E&7
@r2221
CNGCGTTCCGGCGATGAAGCCGGGGCAATGCAGACGGCGAACGAGGCCGCAACG
+
("'#+'('+#!*)'+%*""**''!**%&*!$!'###+'$'*#()%+*((+%('%
@r2222
AATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGA
+
<D;A.DG</=E-129!D#B+,>2B9%2);::1<'!?680H0(1+1E
@r2223
CCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATNTGCTGTNCTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCNCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTC
+
)$68H4@"/%$)#GE!:</)21<*/(.;+45/7;-,6&H6D-31.,2.=*?10,C,(A9"CD2C8(B0;)/+49C&4-AG-"0@-EE)D'B@@4@10$'CA'9!C':<:B(D:BFE;@D941GD9!5,>18CGD<B#>1<1<(<61)A%F75*0/@;:69/CE"F8BA*%H>4B.:B%AF'0FC>H'41"-E&8$?49:;'+30#&*C4F9>H#?DH=-F%.>H1G,C=<-?GC)4BH+=(1E83$7#*>6%(
@r2224
TTNTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGC
+
55*5&'#<GH2@-@8)C%?:'@:%4F("F%;4#0E=)0$=%4;#7
@r2225
NACAGGNCNCTTCATNATATNANNGNATTANATANTGGNNANGNAGNTCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGT
+
)*#*&"(#"(*%**'%*)"'"*""&&)%!*#&!(#'*$&!'("#&"#*+!*')(&+**(%#+!&*'$!%%++'(&+%()*'+!+&)&$!)(""'%%'$++%!&'+')(*+'"#"+"!"++)+)&+%
@r2226
AACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCANAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAANTCAACAANAAGCANCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCA
+
H6!H?=34(G42;-:/=%G+D@0C%3+29%44"/5805".???B<!":0;8F3*,#:/7C*:;//86=1>(5!#HCE+1A=@5./HC@*$@7#(1EG8>E3DHF3$&1$6C59@B'.?;&G$H2.)?+&<D;5A-GH$,93-$0-7"?F!)6'"F3.;)355D"0E$,B!B2@,EH<>??#;'H@H;3(:A9?$>G'"(E,;8+(+:F)4#)2%53/!8H*!5&$.'B"**:!:C=D&86%F6:!&F#)#4EH57&$"-=.078/841D3;!)9@=3A286,AD
@r2227
CACGCTTACTTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGNGCATCAGCGTGGTCTGAGTGTGTTAC
+
&3/!:'*ACBD837.7A!2=)0><C!0F"F491";=":A)8"%%7$9@/;;F@,D,%@;7C8B=*G#8:4A$5H&"!C'G@+)!G<',=6"AD$6,1$C?/++/'(0G:BB.8677'F
@r2228
CTTCGGTATATTTCAGCCGNGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCANCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACC
+
3A74320E.6#2H-)#4-%%1)4.&D%)1=;+-=!:-.++FA:?,8F&>=?6H)5*%?!GA239H)!2%F53C$BHE31?F%D)/(""+=('0(-!E/>:F$G/>)+61'<@66&40HC=0%:>'="3$0A1:@59@78"+@&H(+?G'7;;.C3;7:5@?-609"D=#+64=>:!F>;/"2*-=-#$'%B!BHE6;+F3):;3850<=G+;(";:+<HE!'(ED'-:7<1.*"*#+G89,*,AB2#;>)-G%>C=B"C2!-)7A)3:7&(+7;8>(;-G*H87(5?;0?/2H"&C8AD%"+F).G:?+:%##)*?#*'$E8!4:*#G$936E50G.B/5(>*C,0<%$!F%!DC;94A?3:-
@r2229
CGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTNGGATGGCAA
+
:81DC!E&.#5A>"'.795F?<(48D50.4=3)D&"70C#G3+AH.D,6B''7(+?$A)0&>70=:36*B+G&F;6,F%A<#:1
@r2230
NNCGNGNGNAAANACGGAGCANTGTCGCTCGTAATTAAACNGGAGCCGACTTGTTCTGATTA
+
&!&'!**)%%'$!)(*#*(''+"'*++'#*'')$*"&('"&*%#+%&%""#"'!"+&!!!"$
@r2231
CCCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAATAACAAGGCGATTTAGAAA
+
!5:1!2G%0C=/';##)(-$B972$E1-.4369A?29,D!7!%73:8/;)(.C#A:DG@77-D50C./:>-1$53F=;:;1:<)=H(4@BB6<D3'>2(1>HCA+5.G!=#==2(6,*>D2;+?,@E!.@G4@#8GG0C0B1:72:B:9.=%,;D('B<%/1B
@r2232
NNGANCGNNGCNAGNNTAAAGNNNANNCNNNCNNNCNTNTATNNNNNTNN
+
"#"!!"$!!"$#"#$##""$#!""$#"$!"!""!"!""##!#!$"#!$$"
@r2233
GTGACCAACTAGGCGGAATCGGTNGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTA
+
==03/4)G!0E48$HCAH%FA+#F0BGC2,F/FF8;D=;-3!G7@D(B&77(&H3>2.3<&F(2<H6:CB0F--:>*8!+C?904EB)H"0
@r2234
GNACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGNCGCCTCCAGTTTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGNTGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCAACCACGGCAAATCACTCTG
+
'!#+%$$')&#*+%)"&"++%"!"#(')'$&&#+"((#'$%##(!&&$!$("!!&()#**$(#$#%)'#('$'!)"%")((#!!+"%*&)"'+*%'&*&*'!()%$*+%$&%'(++(#"+!$(#(*)"')(+$"'"*'((!!"*&%%'"#&("$#&'%'$#&'$)#+!*+*''$"$#%)+%#*)+$"$#+!'!+$()*!$%%"$$&%&"%#+)($+"!("()!(%)'!()&*#*##*))*"$&'"")$$*'$$*()$()%!#')))#"+$%$+(%#
@r2235
AAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGACGCCGCGAACCATTCAAAACTCGCGAAGGCAG
+
9'%C'G:A87HCCA+;2>+1'+-(AF!?D19-79"4-%=8"),-;?'(C30,,'<B(0G8<;B?@F5E7:/CA(<=.$(,
@r2236
GCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGC
+
8@B-8(D>.4<?%D+BC8E2$:)G(,F'5"$C0H(":9%27G7G#:8@46
@r2237
GGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGT
+
*F193@*1;@*@,.51?=G,*&>48.>8$E0*E1)<?C**3B
@r2238
CNTGCAGGATTTTATGNATGAAAACGCCCACGATTCCCACCCTTCTGGGG
+
'$>8>&G<<?H2H%==$CAG;84%?#<""4=$FH,<A785=?.HF5476/
@r2239
CTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGT
+
,.#(#4!*;=EH*9%=-D7%3E<0-:C2(>1!#8""!/0E7.
@r2240
GGCCAGCACACGACCACCGGTGCTNATACCGGCATAGTCATCGTCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGCCGCTGAATTCCACGGTCTGCGTT
+
"'0B/,#$36@=,GB))+*-"'C&>,A0)H(#"(04/F*")D*!?H#'=D:,D2'-);H!/-15;&E9+9HD.HH1BD(-$<(41?(B29&%D;A)G5$H??',")G3</-'AC;!.*
@r2241
CTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCG
+
'B>/>$(#@/&"&%D.DC5&!(7/!/*B&5FB0"(49<=F18-3*A'&%*&@*G=GG2E4:0FH2&7D9/0AD@AA6;'8'?@9@6FE71"4+-=@4+%.=<5F6+,%<52:('8B!(41!7'F"C35$EB8
@r2242
TGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGAT
+
/%?G(5>5>B$23B"%)):%;:DF)!.D0!)!E&;B)<!+83/B*B/25
@r2243
GATATTCNAANCCTGNTGGCCCNAGCCNAGTGNTATGGCAAAAAGCACCAGNATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGC
+
%$$**'%!#!&"*&$!*)%&!%#!$')###$%+&++)$&$*'#"%)("(%*+&##)*%%!$'!*'""'!"'!%+($'""!'+(!($&*("$+!!&(!))%(*
@r2244
NCNNNGNNTACTTGNANCAGNNNTTCATTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGNTNCCGTATCCTTCACCCAGGCTGTGNCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAATGGACCGANTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCCCTGTTGAAAACAGCCACAAAGCAAGCCGGAATATCTGGCGCTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATT
+
!*!%!))!)*'#'!!())$&"!$($#!'+!*"+'('&&+$%+'#(*)")#(#$')($!#*("+*()#+&*#&*%$)#%!%+!''+#!+'%$""*")()+(!#%#(+&++!'+(*"+!%'+$&)!'"'!'"++%&*)"!++(+&'(+!*%#)#*'$#&'!%*%+*+#*#$$$#%!!&&(#"(*#*)+'%!+&)!!(!""%(++)')$)%"&)+%'"'"(+&'&'!*$*"&**%#%++'%*"%(##*"'$')*++(*(*(*"*%%(+*&)$()')*!$%#""+##""*""$"(#+&&+())")"$+)%$($$#')%)"#*$'*+)(#*'$#$&))%$"%)&&$)%!'")**'"#"&+&&)"!%"$+#%(!!"%#+%'$#*'#)&#&$%)
@r2245
CTGGATGCAGAAAGCTGGAAGNGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCNGTCAACCAGCAGGATGCNTGTAGGCGAATTTGCGGAGCTATTA
+
%)+&+%%'*%#"&#&'(!!!"('"#++!!!()#)*(+!'&#)%%)!$&&&$!*(#)&!&)*$%$%!+#+%$)$*&%%&+!&$#(%$"%)#(+"!*%%*&#%#"()$"'+($%($#&(!''')#'#"&&!!)(%#'&(#%"!
@r2246
CACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTAAACACGCAGTTTCCCTACTGTTAGCGCAATANCCTCGTTCTCCTGGTCGCGGCCTTTGANGTATTGCTGGTT
+
+*+%##*"+%%+%!)"(#*!))!"'#+*"*'**%"%#'"%)("#!''#&%+()'#**&$%+*#$%!'()%$((&$+&&%++(#''(!'*")+'+'&$+%**)%&$&+!&#"%
@r2247
GCTGCTGGCNAGCNTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCNGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGA
+
#0?%.BBF958G@>C"*##;A/2<$)8#.:&*,8,$H:>1A9HF4!$#+@?'@208%9$9@A7H3-$&!*#!#CG%'H$&/*+#AE"&F1AD=$)+@C3+(<%#8B??.5:HD'D?A..=C1<F!'H%=/#+G&G*A<:%))C8!.;H6%<2.=AA?@GH=E+:/0%5<E57./<,H:.DGD@'6&=.'+9E!$@6H:9%#5C6E@<&G$H,A-);*C+4:+C><+2&5H163-''#G6)F@H?"D3,'G-."D5$265@@"%,!=/
@r2248
AACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGG
+
+9"3>@)5-**7/'/G=>-6>32$%AA17:(*='--6&-1ADAD)(@H?"F4'<*%"DH#:$&A.4H%+7(,6-'(:8&CB'<:./D;,!16F0#%GD1"9F;%".A$:&@AG""21-8%(2-&E:*"6-/A8?..@<CD0&:
@r2249
TTTATNACCATNCCCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCNGCACCGCCATCGGGNTTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACNCGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGAGCCGGGAATACGACGGTTACCCACCCCAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGNTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCAGGCCCTTTCCTTTACCAGTTTCCNGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATAGCGCGGATGAAGCAACGCGGTNAATGGCCATTGC
+
*"+''(+()*+"#%))%!$'""#+$!&($'+$"!+**##"#"#%)$'+&#($!%'(()''#%$+)*%#)$$$#%%$#$!")("*!%)!''$$%+""#$#!**#)*$!"+))#&&%#'%++)+#$$%&%!'&&()+%))+(##$&"*'&!$!**'$!(!*#'#)%%"()+&!#'!#+%)+(#!#+'&*")$*!#%)"+(*))*($"(%)("'+&')')!"%&)$!*'%#%)"#)*)**)*!"#)##(%""(#)%$*&"$"(+&"&()+"&'++$"!)'!'%%)%))"!'&!!%$#$+#&(#'($)$)"'%%'))(!')$!)(!)#**$$%)'#!#+)*($+($##&$&#)(&#(+))&$'#!(!*(*'("*(&"$($#%'"!&*(#%$!"%*'('#)+*#+$&*&!$(#&!**%$$"'*)$$#!"%&'(+%'+)!)!'+(%&)+)**#('*(!+$%$'!&)&+#&!*'"'%'!#$('(+*!(!$&%")"$""+#$&#+)
@r2250
NTAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTA
+
"<$#@<?3GCDF0#."9:B5%F.G*14B4F7D;,-92"//3.%&B47204B'D=/7@>!,==<H:)F?:C$$!E1%?%.?F@'C$?$%-GE4+31/:7
@r2251
TTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTT
+
3"'%"%-F.A64$-6<B8*G-);$-+E(=%='%*=H,7,.#"2D//53@/4C!18/&<2+125A&G:062:7(2F/0;;>7+0()%!C59=1@B81<D.2.(0;53GDG<:,;&>*=@!6425>E;C
@r2252
GCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCC
+
,7C@BH:#&5;#1#0H+$96.E<:F/E0<E@-9(1&:0,6/E;#%"9<1':#*.8<;=<#!#@
@r2253
GGGTAACGCGGNAAACAGCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGNGGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAA
+
6B8%=)#/;-HH&?E<#2=)#3HA"'C$HEB:GG4)+D&EG?<(H6-=(EH#D1*?4'.233B&+'>D<;CHD;H7'*./1+6/)@7$FG'6!/8;:GBE;#C)655/"HH10H#4-.,2DE6/"8A9%$E#351E-C7B=F;F?B.05)G&$;6&/5(=,A<=2)-51?F-3&H)*$/'&)
@r2254
GTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCG
+
/A,$1$0*6<B8,")>!;"+:>#!$3&/$%?3C26B+G4<?5
@r2255
CGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAATCCGGGCGGTAAATGCGTGGGG
+
=;4/8(@F1E:,5"3HH@#E-"@5&+'G2:1">C6;:G(4'/H*&3=(3"=39'=9E!6;(?FB4/70$%AG<35D?6D$C,,/16-=-D-.&H8DG4F@1?/#/E(%?8%
@r2256
GCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGNANAACTGTTCCGGATCCGGGAGGCTGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGANGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATNTTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCGGCAGAAACGTTGTATGAAATAANGTTCTGCGGTTAGTTAGTATATTGTAAAGC
+
"9C3"86B&5%)'/.+#FC#BA1F#E$BC?&H6465B$D0*>E3"4HGA1:448G=%2:<(555<9D"-)'6:;?!5G3G'A4>;).</HH&"<655F!F1B?E;'A$A3,+F$.+4$(+GG,/*<6%%!%H.4&(%!8HB#'5>GFC>+,021H'?09''%7<2.%D)5?<C(!.G,D4DHD<*>GB;.@*B+!3>37F&DC<@3<;72B:816<+0G:("EF.EC%#&(?2@56&*=;:D//,F/C*EG(8(G"E>;CA/;)@>F@E"B<>D"$0>C8#%;,+"*!0F#7(1#$>5@5!63D'!+<:@+($9HD17"&+=7-+=0)?3&"56!>;$*3F+*;$.;0(HD'2,=3+8571A';69$%0H8:50-881D"-F;
@r2257
AACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTT
+
!/5!'AD95><!'1"46(8>;.B11F%$H@+C</G5?9>D47E5G+8*6C,CD4;;!2)3%=8;-,.?(*GA)0"698H53H'9?&>A"G)B-*/7H*8A6(C//41;5$&G2+-A&#G@3G#"-B'2@B3)>@H0H4)(7HA@8'BG74GG).*8$"22%-6(*2-&@-)'*6./)#8(6&$<;5A0-
@r2258
CCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACAGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGAT
+
'.$"77!'$@(ADHF#+B<&28<&/$19@)3?DD#F@G<+G=<!'=HB>GA"1@@AH,;;'3-CGC?02#@">A?"*-5,G:8GCBE7HA)-"954:!HBB??**:*A*
@r2259
CCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCA
+
C;B$#?E1%96A62H)=,/.E)G7DA.0(88+%;@3>=:86$B(
@r2260
GTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGC
+
.="64?F#/?=%61,8&3E/@D$G0$4-3E(13031AE%A%G304D,H/E;9-+A@
@r2261
AGCAACGGGCAAAANGGGCCGCCATTNATGGGAAAAGCCGGGGGC
+
00=*&A6>.G$$#)<4F+%;18%9EEBC&)74H;)&$:2BBG6='
@r2262
ATGNTACGAAGATGGATGCCTTTGGCTGTNCCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGA
+
*)5G'$76>!#732%,'+5@F".&D71/:=@H2!3D&A4E<56&H667/A(%5-($32<5$GG%?91>"
@r2263
GTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTTATACCGTTTAGCTGAAACGACATACATTGCAA
+
B+:;/4#=&?&(5(%,%@?9D";D7?0.@@$'B!#3+B=6<:*E4%265#4C(:6D%8C9;):+G9634%
@r2264
GATTAAAAAGTCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGG
+
7DA0!,8'*5);B/BC*9;=/8%1)*!/1A3)&(C8-(:?4A&:26$90(E==;"
@r2265
CAGTNCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAG
+
%+?A,/7=7,23D:0//#0;0&+1@E?5(0?#?0(/</D?%>F,'&@>:*
@r2266
TGCNGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGNTAAGGGCTGTCGCGCTTGAGNATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCNAAAGGCGGTTACGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTNGACAGTCCGGNACTGACCGGAACGCCAACAGC
+
+.E5*+%D=4%49><%;!*DE?5*:&-;,!9D40FF/!<A'C#.A93*$:AG-.0-;.G(8E,!"7F+A'<($4<C53',(21$"5C&0BF5<$*;/,F;C$.%<F,GB=/%$C2,%8/3>:>3?H60D0*448F%?1:4'>#!6#B6$,'1%43@+/:+AH(1CF?2H@8<5.14F5D7/77$>&7=$.<$77"B>@168=43E#!6$8,,>..3E(3;21;6C=3@,=6)'>7G79B*!:#(=-
@r2267
AGGAGGGCGAATGACCAAAAAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGTCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGNGGTTGCAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCACGGACGCGAAGAACCGGAACGCGTGCTGGCAGAAANCCCCGGTATGACCGTGAAAACGG
+
,:)&'3*HG?6*/?1,!9:$=,-F!"##3;7/(==%@*97,=,"2&.%E!71)'F$G>.+:F6?-46@E7F5G?3G5F@(DDFE3EC/'EG0C&9E?4*0*7=3;7F"@=1#8@FB*3%E.*47-*G&"BB880'+G$$.2E'C%,BA>D,'G)6&C26<3>)E44E4?$+B/?&==#"('!6,()+=(!?!430)*7&%HA<E1*6100)H7$6CFC''%:4:,%'F-$?$&%%?*>.+DFD;3*<HBF34(.G3H
@r2268
CTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCA
+
GG#@),/E9B:HADD6:83/E;9%A%=10<&16-H!3C/.5&/),**&6E?20=82*?@H8%>&"+A-+7(EF3%8#@H)!
@r2269
NNNANGNNTAAGAGNNGNCCTNANNNCGNNNTNATAANAACAANACGNNNNNNNNTANNNANGANCANGANATNAAGGNNTTGNNANNAAAAGGNCANNCNN
+
#"#!!!$!$$!$!"$"$""!$!#"$!#"""$$$#!$#"""$#!$"$####$!!!$$$##$#"#$!$"!#$!$!$"!"####"$#!$!"!$"!##"##$!##$
@r2270
ATTGCGNCNNTNATCCCNGGNTNNGANNNNNNNNCAGCAGCCGAGNNNNTTGNATNTNCGNGAGTNTANGGNNNTTTTNGCGNGTNNNNTCTNGNNNCGNNCTCTANCAGCNAGNNNNNNANNNATNGAAATTANNNTATGNTCNNNTTANTCAGTNCGNTGCGNNGNNANNNGTCGCAANNGNGCTNGCGAACTNNTNGNNTTCCTNCGGTNTCGANNGNCNANAGGNGAACCCGCNNGCNCNNGNNANTN
+
$#!$"#$"!"##$""!$$$##!"!#$!"$$$"""#"#"""#"#"#!"!!!$$""!#$!$#!!#!$$!"!#$!#$#$#$#$"$"$#"$$!#!$#!#$#$!"!"!$$$"#"!#"$!#"""!#!####$"###"$"$!##$$#$#$"#""$#"!$"$#"#$"!#"$$!!#"!$"#!#$#!!$$!!!$#"#"##!##$##!!"$"$"#$#$""$#$!$"$#""#!#!$##$!##!$""!#""#$$$"!#$""$!#"
@r2271
ATNGCGGGGNANGGTCNNNGNNTTANNAATANGGANNCNTNNTNCTGAAGCG
+
!$$$"#!$"$""!#$#""#!"#""$##"$!"#$"$#"$$"##!!$$#!#$#!
@r2272
ATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGA
+
2<:<*D,GH0E>1&-":;<+691"&$AF/6/)-:?637H#''/B&<6!"#@@H-#7"=1$77>4?/;>8(&BE87(2A//61F4@;0'8$8==,?=C074@!!&?E<!7#(FG:C%'CEG<0.?:H7!!
@r2273
AGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACGGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGC
+
-3D"7G0"/,G:1)%#08B$'857*G#+6#"+4.9.C(<E-8/)52"578(.,$G76(*<-9B??<*(#!9B*#4:.H!%/&*A>8
@r2274
ACAATTTGCTTATGGAGTAATCTTTTAATTNTAAATAAGTTATTCTCCTGGCTTCATCANATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCN
+
&'''+'#(#(&'*)$'$$!'#%*#)"))!%&(&$**+(#&*'+*&*&%('%!"%!+"!%!**"!($)&$)(!+!*#(+#**&&!#)#('*"($)#&"!$'&
@r2275
AATATCTTCANGTNAAGCATTNGAGCGATTTATCTTCAGAACCAGACTCTTGTCATTTG
+
%&$'('())*!!&'$'&)&&"$+)*'$""(+)"(%+"*)*%*!()+%*##(%%!&(($*
@r2276
GCAAAGATGAGGAGGGATTGGAGCGTGTTTTTAATGAGGTCATCTCGGGATCCNATGTGNGTGA
+
(31*)B0"7"AF41AE<?)%"8G3E9A?6.:"?/7*#@95C(<.96'+G9'+,D?47C'%>/<)
@r2277
TGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTC
+
;%C$/4)$#D9)'>37)::#%C#648%8173BD;?@<)(5%"5#((8=7&B01:&<B
@r2278
GGCACCATGCAACAAACTGCCCAGGTGATGGCAGAAATGGTCGATTCT
+
49!#(;24%#)"&AE&4&?$=!)<<3&('83(1:/A=4,75C"45&8H
@r2279
ATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCNGAAAAAGGGCATCAAATTAAACCACACGTATGGTGTATGCATTTATT
+
@;,F"G++>BBA>5*FG-(?D,;5'6;0599:..54!7"@'&9>:37-.*B*3E;;"!.AF&6A!*G4/=()1.:9E6%9=%17@
@r2280
GGCTGACGNTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCTGGCCGGAGGCTGCCANCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAG
+
)62%#"%?,C)D;=56"-E+452%%/>,+6A;HE0&612%B$7$"%.>4H&()B27G!D;"+3+9D3=)2+"8$;A3,=B2BA5255<9>70H2&/F%+6>/$'-.F!?A"+A&D>&'=8G:%FGE7;F&EHE.(=H",&
@r2281
ATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACT
+
5:D,<$EC/*:;A9%9#G$.5B$.;&2(.@)!DA'?4!0>7(B34C?"()B96@'52(70,A"D25$A7'.#;2<$.)<#+$F0B7&3!AF#3
@r2282
ATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATT
+
91?1CH5*FD#7)F,B"1?;E*.?8>:..$1*5E2)(0BF?G:6(E9'>?B4D-/A/3.9*.)C9.&G95%/:)>&E)B#(-/#=-96894>G:!9F,G)9-"E5'(28/E?7D+F.>D'7C=4F-?:',/)(>A4G167E<H7=2<:$!;-*=5G&,+GA1/H8A5>$+B&?<-=)4#8&&;!-HE=1'6!F#,>"4-B=$!@,8185:<6:6"C>8A)1*B#$#3#'A5+4C6%9("<$%9-;'(.-1FE06=-="81<&44".:7$F-FE59=<+$(:559C?*EF+!;<3,8F2??,+42G-!!F'.".*61H
@r2283
AGTTTAAAGTGCTGCTTGCCATTCCGCGTAAAACCTATGGGTGGAATAAACCA
+
2<2,@">/H(@2>)9G16/@A:H/D25%@46&FD>"7ED((,6+'C7%*@18*
@r2284
CACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCNATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGC
+
<808=$FC"181'B-@D-%.4#8"9B)ECG>9@'4<6@;G2?=62,D.$E"1>0EC/D=C"9&74&B4,C,6@:!>10(5=%CC7%>+-;?H=4C@:91$=/<G4;7*:04:*(:7?&=8+!@2H>8//D+F3G-;2&$6;:>6
@r2285
TCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTC
+
B;B4&;E-86CC.8ACB3B:F,4A2&(0G-98E;=;:6")!D-:!@4=;!B,7@@8><+A@=G//@;A&!</&D'7'0(!95!9)-72?H7AF":'04%E
@r2286
AGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAA
+
788'#2HE6<=EE11D5A9F.=+=&&"A61%83/F@9<$4F/623*1"?908&60'F
@r2287
GCGATCNGATAGATGAACGCAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCNGGAGGATCTGGAACTTATCAGTAAACAGA
+
,62<EE:@2BE7$,A-5FB8",%&5CD43A+='=0BG4@''."'*%4;$6@4(*):>/?F@:-4+5%$0*$44B09DD?&/7HD!69?78+("
@r2288
CACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTG
+
A//0"!.:5-3*H5:&03$<:BD8,?6*=3$*ED&.8,<3*DH!>/6$2@<$2GH96!"0<>!(&/H@/!&:F3"7007EEC$$;=('*35*-926/3=173(2D/:!:D:*4DE?./B:>'2?6+'??,9BH;,!"!,"BF,2!6-6#@-F;/7,A?0$$0-(
@r2289
TTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTACGTAGACGGATGCCCCTTTAATGGGGATCACC
+
<62A!1C:G6%8-:%+EF:2%,#E>-D/#E5/"/5(#='804C#$G>F)F+9;0.+A9-#15C+32"/9,71A#F)2D@99=+EE6H9B&;-=>?2C$5-!/>/$"DGE$(E
@r2290
NGGGGGCAGGTGAAGGACTCNTTCGGCGGGATGATCCCCATGTTNAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGT
+
!6E9+>@A+2C@<//))5H$$/4=%F';*$3@H*A)>)B3HEG23$?9727:@AADB-5FA<&2(>).33(5<(%)%)1+-F7D=@6B-/10C)D%CB*637&,A'E3D**EC<F;8<5>)
@r2291
NGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACGCCAGAGAAGCACAAAGCCTCGCACTCCAGTGCAAANCTTTGTGTGCCACCCACTACGACCTGCATAAC
+
&*+")$+'"$&!%%'&&$$!'*!$&($#)+'+$!+$&%#!)#*((($"&**%+)$$+)''%$)()!((+(&#&#$*$$'$*!&%'*")#)!#!'%""'%"#'!*+!&))$
@r2292
GCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTCAATAGCTTTAAGAANGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTNAATGCTTTCACCTANGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATNTNTTAATGAATAAGTGCTTACTTCTTCTTTTNGACCTACAAAACCCATTTTAACATTTCCGATA
+
D<0-BH>FA960B/+<#)4A3(2(-'0=$E"2#')B-2?05-@#7<.=(.F0H?"/2?*3?'CH=33EE%:-!=;E-1$<(7:,/G=32CD$@2*;1704:9':@,)9E*>D+85%,B?><B3?>7#"GE;3#D71B>EA,#&AD4,-#+7,&B+!)H6!5G3E+B:6$9<+"9@G6FGG$<*FF5&33%A8?8%%!0"/H7G9(96,*2E;19F1C8%"*@68+EG9F*:H/>DF->CED1:<#
@r2293
GCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAANACCGGTA
+
:G<=,9@-)5?6=/E%&G"5":0";D'&0C2*8;B464;?@?D.%G(%-H(
@r2294
CCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGNCATTGTTTCTCTGT
+
7GD='ECA&F?%4+8G2*$$32-3)?EH:(>0&!,$<764<:07+%%<62*?0=7%'C+G:0,!C%4'*-2E.B2D4><>A49@-,$'F$:!-;GD=(,;#;=9<.1*<5-/))2F=1-+?/D#43<F8B5(0"1B07D"8)A.H4
@r2295
AGNCGCNGCCGGAGGGATTTGAATCCTCCGGCTCCGAGCCGGTGCTGGGTACGGAANTGAAATATCACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCTCTGGTNGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAANCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGANCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATNCTTTCGATAACGTAAGGAANTATTACTATGTAAACACCAGGCATGATTCTGT
+
*"!%#!!++##"&*!%(#')!%*"(!#!!((+$*&#"!%"*!($)"*'%""'(#)&+)&#!)(*)!**%((*##''*$%&*'#!!*(+$"+!$'&+$(""%+)'!&(+)'#*(*&#)#!!#(*$"+'*!$*'#!"')#%)(&*"""%&$*')'")%$*'"(+*%+#(*%+""%(&+'*$()&$+*)&%+!*!*)%"%$("'))"'('&$!$&*$'!)('*")"'&(+""%)#++#(#()'!")+'+*+$+!*&#&#$+%(('*(*%*(*#"!$!*+)')'%'"&&!$)*'"$!)$$&$'&(&&!!!)+'$)!""&(&)(%)')+*!#)+")!$")$((%#(!(%%#&&+
@r2296
AGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGC
+
"G42@"552(C2=C=GHEA+H.<(01B,8=A0"9+F;$D$%E<,2(EF
@r2297
NTCCATCATCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCC
+
!%)()%(*'**+*)$!'!)&'&$(&!&+%$$+#$)!&$!!%&'%++'!'"(*#&#%!&"*%$+#+&(&+")))
@r2298
CTGNTTCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCGGGTNGCCATCGGTTGCACATCAAAGCAGTCTNTCAGTCAGTGCGTGAAGCCACC
+
%*)%$+&$$+*!+#*&(%!%#)$#)$"(%#*#"!+!$"(&)+)!)%$((&"%&*+(%*#'+&#+$#*+**%("#$#**$!'!*)")%(+)#&#(##!&(##
@r2299
ATNTANCTNTANNCCTTCGTGATGTCTGCATGGAGACAAGACNCCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGC
+
"#!)%%$$!#'(#+%++++#($"#!!)")$"(+($'*+&!#'&++$)%)'!+%&#)%#'+''!**&(#((&$('$%%+#%&!
@r2300
CTCTCACTGTTTTATAANAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGGCTGTTTCNTAATCA
+
C4-#H&@<'-+?B;'6'5!;;AD,+:B@*(1/5=8%/9"$"25?H6)3H51GE)2$1!*AA(/-><@/#,;<!29(E@%2A%42A+73/$=H
@r2301
TGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCANCAAAAGCAGCAAGTTCACCATAACCCGCCACATCCACCGACTTTTCACGGTAGTNTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGNGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAG
+
-)-387.F$8$-701;?=!9%6DH(;H9;(A,7?/,-ED'@C9:3>81H',:>)@F?(FH=@9CC&13DA">G-6>="3+GD.C%3'9%8C0.&=07?'%('9G)0<@6%?;>(98-#+H@>"=?(0)#/$F7&9484E79>G:(E-"2+C?H1$01+G$C37B+)7.1!>-HB#:@5;3G0!?;!$%0&"-&D+7CB/'8:&*4A'4B,E!?%@9")<<C/'GA$"F@F:'5=+D#736=?F;%C2:,1A@4188$1+B$"17=7%.26C@<,;$)(C+"B0E;.=
@r2302
CTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGNTTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGG
+
.F.7&:G!-6?+H6(7.)??">B?C;:(,<C)%BD2A?1,/!B)7>'G"*%'*2,9,:6C197&+!>:?1#%"*-!HE)(
@r2303
ACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGA
+
D;<90:="!DA"%)H(6FF$8;'2H9<>",D(93F(/"G?G-H
@r2304
ACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATA
+
6F8@H)@,/09DG'("%;')G$?7.1/<=C20+<+$D=';
@r2305
GGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTATC
+
A6.<B>%/%/)-<)C$F?C774=3&;=CA:2B%C6%G=D$.@:&8GG+77E<%A%#>''BE2>;5H)5,F2<69@D!5A0+7G:!"'/<#:=:&E4$C63;H8/-&6
@r2306
GAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTNATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTAT
+
27++@=)G;)*(+BA86GH4:<E(6H1<4,B130$,A+G&71-.7+*.G93&($H,%.;6+0A?6/./%B=";G;8$#"H>4C&+&-H$!8>F="?*&5C:F=@'+;D8:CB(':1&01C;+-0H(&1D5F<G,
@r2307
AGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATA
+
H(3#-0'-C;CF"?#&>@G=9@60F%AF3#)3$<;#8#:B$F0<&=BF.$#3G6.=40:+0E%?H!/A(F.F!&09C4&;@"='9.--=G,*10@>#**2$7E'-@'E0"E)1;,+#47!FH?7;,"9;($F!"!(4=69>C))C5,$,$@
@r2308
TNTAGNNCCNNAAGGCCGGCTGCAGGCAGAAATGCAGGGTGAGA
+
%'(#"*"'(!%)'&!*!#+!##*'&!($)!"$(%+$'"&!$$)"
@r2309
TCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGNTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACA
+
,>/-%/GE"$?C)='@F)==A)"3";7A?4;&,-H-2"9"&;!%BGF;45237:=0$6,502*-=H5%B9;H"C&&D,B##5?":#(0.-?F)B*A7(,+>0.$HC!1<25+F4!653E>8?5C,EEC$;$;!'@-<=(H-0@?*9C/F8.@#237:08+G$*"(=F$33+@5#C6=A8!?=&8:C/
@r2310
AAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTANTTTNTCCGGTGGCAGGACG
+
CG6=A#H<.B=E$$E'=A8;<H(1-@;=88,;;D0""=28HA)(H.75>C22%7432347A
@r2311
GCGCANANAANTTNGCTNGNTGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCNG
+
)&#$(!'!(&)!!#(!!!'%&&+(!(""(')+*!"%'&('')*(($&(%%()"()%%!*"$!$#+%+&'*%"()+')$$(!'%$")"$)&$&&!+"$(&$$)&%&(%(%(%$'$&%$(*)&%%)'"!)*"#
@r2312
AATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAA
+
792E0=E6<-,*7B+=;"'69;>9DBCE1HFF&&H?F.&.G?B0&#F9D+A"?.14/A6=>B/F38H$@):D:.>H1.0$/!6'?
@r2313
CAAACNCNANAAAGCCTTCTGCTTTAAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTTACCTTCATGNTGGTCAGTGCGTCCTG
+
**#*)!'"%"+#*(""**$$'*"$&"$#!#+$(%*"(&(+))&""%&&)&#$(+(*)+()'(&!!%$*!*+&!!%%*%(+""''&)$#&&!
@r2314
GCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGANAAGGTCGCTGAAGCCTNCGGGAAGCTGACCACAGACCCGAC
+
-.D19+9+74&A%+/34)-(7("F')86<&?57:!%9.6)2H9H.%)74.'!4(2#A1#)8#:;-<3,4.7!D'>::
@r2315
AGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGT
+
.:#$9#-/B,37630G$A2>(D!B+,1".8)B<H?-8F0-4>2.""-H-2F!H714H--
@r2316
TAACATCCGTTGGGGATGCGACTGCCACGGCCCCGTGATNTCTCTGCC
+
%;5*36/D"4/A6&+$'##B"*;*8G07C>?/&6C/"54=3*?H!>2!
@r2317
NCTGGCAGGCGGAGNTGCATNTCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCCCTGNCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACG
+
!+>+.G5D1B*>ADB'$-C0+7:(7.$@!*=%0$3.B<451.8@9D!3.$&6E8EGE!G'F0&1H.5D'3->16=5!;;10H9?(6$*A1H<2!D+1%B5+!@BGG8*.;F-.7$HG5G*<,?#7.)!@=60EGE)0#H$E)H6#/E'));%@+#&<>A&3%40@%2!
@r2318
CTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCNACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGA
+
,'4-902G<43@<@=.$'!;83&4,&>=$/#+9D/%<++,>'.&*DF#+HB95'0=69-*-AGA-<+G4A'(/-DD'0E)'9@FB+.5&+)!'=@9*1&8A7.2
@r2319
GTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATTATGGGGATCCTNAACAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGG
+
'/1%BE(.):<%8>C6;>,:E('%>%D$G-5<8C6(C/@!<G;*2/#/E1@?+$,"0H&+'7'1"#/6).0?2CC)##86++54B9@2;+>01.)-(-(+?";H8G=3%4:BD&D.?BB..:>5%-'/-5A5D);%(E&=/<.3+-$(:?A=HA@=BB34B%F
@r2320
TCCCNCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCTTTTACCAGTTTCCNGCGTACCTTTGTCTCACGGGCANCCNGTGACGCCGACTGCGATATC
+
3BHE@$5*(G.:6B*0%!G9'C-1'%4?:>1&!'D05%1&&;??=F#.)B*+#$7>(FC0<CB?<B&/8;EC315;20C")1:$$/B83D'3%$@FCD?4!;$(7*9H+7C8A5+9*7@!$C55'@@41
@r2321
GACGGCGAGCTGCTGCACCATATTCCTNAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACNGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTG
+
4/GH?3-)<9:@9'<2D,G4C4,C5$#65#7<-;'A&1!:)1&,$?76"6)%26"1,7FA;39G.>GB-#(%A1%482/3'642C$%?H<<"==%&--;F(>977C89H?F!D!E&7*B1HA7&3$"#F,4'*@<=D(C=#:1>@:56,G.HFB!;'#CGC;/(
@r2322
AGTGTGGGGGNGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCNTGGCCGGAGTGGCTCACAGTCGGTGNTCAGGCAGTACAATGGATTACCGTAGGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCA
+
:!+@0*>1)431'+963!*6!0:A2+#:)$./D#=*;DC1@D8%635CB9@&@*,G:,.?/$7/!G*1(2A6%9:&D%-&)).E'9!:@!04B)()5;+H,.8C+;?.CF,1:D1*CGECF<D'74B0#61F&@;:;<BF(+(H/G%@*H>>5B*H!?300@+&036;F=,#G44@AC6H6'<8D9E(.*92+GH(A-4.3H4?*;46'8-90@>"==0",)F%!1/5/<!C/%$"C9:!9,?)$3E)G5;+4;$4.$<
@r2323
ACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAA
+
FG0*+F:AF&G>>D>(G-E#5'0&=:'"4"F(;)6C<G,A@00H3.47B@A>5;!'"$0A=&!E$>%:81.EF1?;?BB$+GA(66H30HF/.@#<+</3-@'&A,/98A@"-:2$:;BG2-.4&!A-":3?1
@r2324
TNCCCGTACTCAAGCTGGGTAATGCGCGGGTNGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATC
+
,*0D?.0+'3:(?*,>&8C84A,H89;:*@H>@>7FD62@1:5FD6%*@*E+A$,4A4=/.%%'%.?EE!6+9><.
@r2325
TTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTT
+
%87>@=*G*3D/'D$,>E95-;7="%1;HA$1?B$6D@;@2//;*@??.09=-%BG)F-41H?=/'%&1+7.*0+(#10C49;6E9:B)#!;-.//0'3/83!'E(1
@r2326
ATCACCGCAAGGGATAAATCTCTAACACCGTGCGTGTTGACTATTTTACCTCT
+
,%@F32'6:$<42;1'.15/%99/,(%,B*=H1;51H/77$D0*C&&G>($73
@r2327
AGGTGAACGGNNNACGCTCTNCNCNGCAANNTCNAACANGNNANNNATGTGGCTTCGGTCCCTTCTGTAAGAGAGGTG
+
'&)*"%(&'"*#'&')("*#"%!$!#!(%"!%!'&(%)%!!")'##*+%'!)%##'*'(+!)'#$&'(*#*(#!**)"
@r2328
CAGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTT
+
47''G,D"13+DG3#<4=@E>H8!D6GF"<>)G4#'/D&-.%*%8C54=E)$.8%F6%11F61,$A.*:0>7)(GD?%G!7;40/A"<7.BE(:8H)634(@
@r2329
GCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGACACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGC
+
A2F($52?E>CG(#A'DDD?=EC>>A$48$066?F>H5)$(,B?,4,@6<>3AG-?4(BB#@?&+.?*)@4+B#3!BC37,9C:3&G6'EH@(FD+2C6=:7+F!,=%F(<G-'D.B02#,&C!1/8)9HG)7$@=/*G%B&5"@.'73=28&8>""!>93E<7
@r2330
TCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGA
+
=ACC5+)&-?,#7(H?.44@*@;0+%8+"?<$G>+2CH:C/G255H'EG@2?214=
@r2331
GGCATCCGTCTACGGAAAGCCGTTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTNACCTTACCGAAATCGGTANGGATACCG
+
0"<5##7/41)?AE1G0.&)7.@-/=>&'(#*#<%"3!%@9$F/8*38.?;'="4+3&.E9!?D:3!F+.,=C!AC3.$*$BCDC($?@
@r2332
GNNTNANGGGATTTACTGCGATAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCNGCATTTATCC
+
%$!(#&(*+!)+%$$))+%(!"!'+$+$#*')('''*))%(*+&+(+++&++$(##!')!&("")#+")$)%!+%)(+))#"$"+!)!"#(*'$&&+&'+*+&'#'
@r2333
TTCGCGGTTCCAGATTACCTGCTGNTGATCAACTGNCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCG
+
;<"8G<908-15@@=)H<6ACA99!;8@7.9H1%G8(3'9:200!H96,7C!D7=.>;BD4A'$-F509<;&%
@r2334
TTTATANCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCG
+
G.4>-;6$EG&6@76/#=28,7)H582D=92!9<H(A014"#$GH%.EE,!'!.:8=G'0;"@8D+B9A3!=)*H5">?;F*,:?F*-64;'@A2<2%,24E*+4,BC>/,
@r2335
AANCTGACAGTGCTGGGATATCGCTCATCACCGGATAAATC
+
#'$*++',46>@"8B/EB9%A2&0.E+98@@*22&)%%#E:
@r2336
GGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTG
+
<%5B:C>5&/;8=/37=<.H4#D%D#15FE-EC"1:=4/CD=="GH.#69>>)$8@F
@r2337
CAGGCGTAAANATTGCCATCCCAANAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGNTTCTTGGCGG
+
3+!-;3C/%:F0)0G+>0$*778;>D:E4B73D16#0:#>+468!!G,#>9?:<G$1-063H@9590?43#5<6+?@BH1A5);//<.;3?EH!$B%
@r2338
AATAATTCCTTACGTTATCGTACGCNTTTGCTATCTCCTTTTCCGCCACTACAT
+
<;8<.'?0:;&5$=6;+977,7"6@7BB2<H4<-8?01>?A>-**>$&*+0@CD
@r2339
CACCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTCCGTGGCTGCNCTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCGTCCCACTCACTCCAGCCGGACTTCAGGNCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGNGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAAT
+
4$C-:)547H&6==B2<+#%EH?7;1+B89.-?2#=&*)';A6/F62BD'#E0"A43?"0,-+B4#><1.!.=%6.4G0/GD0'68.)5&A6!*&H.*E25090?'@$!1#'A,8+!E/F0D&#A!<!9//%#F"*A<4-%#%$$'*<'"$.!*1;0(DA-=50&>-1)3);<>+27;6$D1G!$B:7(9?**1!*51!!?H06+?:A6"C&D@+*3?$/6%?@5'+H@"E0!C@A>@H=-(3A'0>:G72E=6<*,>9A96AD$8C-,H:29;*,H'D$G=
@r2340
GCCATATTCTGTGCAATACCATCAAAGNTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCAT
+
0=97+DA5/#/1"08(6%%@7FC+F5;&=2.#+7A#:+13-?(,1G#+(4G?-7/F<&/.'@("9G6A)*'DHAC##CE)=DB,9,4>@"1>D:49/0AD&564FCA$2+@+H
@r2341
TTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTNCATATTTGAAAAGTTTTCATCACTACTT
+
("+*)'"&)&%#"'&*+'%"'''!&#'#&#$)')$$%&##"!&'#!"$#"''*(''%!)$+")!$(!+
@r2342
GCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGANAATAATAATATTAAAAATTTCCTGTGTAACTAATTTANTATATGGT
+
*.3>(G;+9DD#;$>9?&"/F%@&G/H&B21-E(5889/%;F;:AC+=2)#-$),9*H&?>6.<0=9**DBH"5'2$B.2770-CH;E1.
@r2343
GGTCTGGTTAAACGTCAGCCCTGCCGCTTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTC
+
899>B/&+;H/)BC.-80&+"G,?AB97(4=7#;+;#<+B24>CEHEE6+122),H!'<F.&@C"(6
@r2344
CGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTA
+
2&%4E2;311/3B&+?CA?%4E'35->2/:<)34>A;0;8A6*;+25)
@r2345
GCGNTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACC
+
77?!D0CA3G!8G?40=05G5;B85(,!=A:/(;,7$$/?;9)+1;@3C=ED
@r2346
GGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGTCGATGGCTGAAGATCGNAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCAC
+
BC-$H#9=AH>9;"9$@11:;@(C(#!!(B>>(2854!"E'0?<)"=+=013,94?@C4A8F5?AH3B,)D"#;,#-""3:)352<*<C;DB58)D$4C(@,9G0$562C#@H%)4?3/7AAA)?'#;3'/$,'"5
@r2347
GGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTA
+
3"*+0<@79!D07:65"#C05&3>&0?52:,.D42A3514.,>%@&
@r2348
CCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCNATGCCATCAAACTGCTGGTTTGCATTGATGATGCGGGACCNGCCATCAACGCCCACCACCGGAACGATGACATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAATTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAA
+
5@37A+<7!*9!G@0-8C%@0A?2&2C;=))1?9,7$";6&$=$A0,'4E)&=BC0##$HE@630=$,1,/5.7/+B9.#%2!%"/%"E68;23C196':<H!.4(<H4)6=G4GAG27G8=,4=GD)D-E876(%G<)2!&>?@;G#=)=3'%1@,E2.8H,-C;.GED3@==AFA%-GBD/>7H2;60<2D5(9&:.5$%D@'3558FA%B95-#H6$/-)D?15BBE6@=%010-.GF/G>$A!E"3G%32*1C?.5E.6?;(+635C<41,5C2
@r2349
AAACGTANTACTANGTGCATGGCTATGTTGCCAATGACCTGCCTAGGAATTG
+
&*)&$($%$%$&(%)'')$*)#*!'''+&''("%")%%)%($&&+&+"+*!%
@r2350
GCTTTGATGTGCAACCGATGACGACCAGCGGCAACNTCATCACGCAGAGCATCATTT
+
/B-&0(-D4;.#=/B%,6A)1%2:4<51>5#1"A9"9;E.E'-/A'!#DB4"8*6G#
@r2351
NTGGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGCTAAACGGCAACTGCCGGNAAATCCGCCTCATCAAAAACAGCGGGGCGACNATCAAAAAACGTCGCCCCGGTGTCATGCTTC
+
164BD5F?8GB)(+0)67E@E596=E48H@42!&D=?)9@F>@&2"H$-!)?&!"')B&'/=$">20EA0>;=+D?5:B5/.*#B<A)5&*'/?35(#+8H)G'5;7.7%*B?EE-"#8A+1&(
@r2352
GGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCA
+
+"DH(-26)?.-=68-?-;=%+6F?%D>=$+4G5#-6'HC*(3A
@r2353
GATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCAT
+
/!222,2*!)3$&"HC6@5:,,/79;33>E"A?<%G%116.%>F;;&=2!5<F+,$&92F>1;!;2==F%;8$=/4E9@C68(E,<A3A)A8?8'*C%>&9$;HFF+',/8'3.009E@
@r2354
AGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTANTCTCGACGGGCTCCCCCTGTCGGTGCAGCAGCGT
+
?->@)C=(14@G8&3D(#$=D#B2'?G%;<*>+="#G0&')!*4BD&;H!*CF),H,"2";%$9DE.G0#@3:6>2@''3.0EG=>H8@-(!F=-7)3HA)#>4-0+*F&<B,*3.8?A0GFE)!1;9<FH""&")2&/9CAG4BEHGC&7"F"#$13;$$'?02!=.D!/>(0@(8E(B>6.F9@F=4H,;0'%-5$9EH6D1(;>-B18&0(CH%#E.;?$92EA0$@5#E?21
@r2355
AACCGTCCTTTTAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACT
+
-?%=@C)&#D"%F/#C<58H)FAA%F:;(-6B('7@6%.%'E7$5)7CEA&&@&
@r2356
ANNNCCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTG
+
$(+"++)*$$)(&#+!$)*'*(+"'*&)+*'%&%"&$$#(%$''&!***+%#'""*$"%')))!)&$*+'(*%#"'#*&("('$+%"%)!#%%$'%)!%%$&$(($+%"$!
@r2357
NCGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGATCTGGGATATACCGCTCACCGTATTACAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGAGAACCAAAGGATATTCAGACGCAAATGCCTG
+
,H*790D9G,*C%?A1#FB=7)H55C"<0E85':?;;%%<C55!33(C/F5B=C;H?B#>"@=!CC>CD(94+>=A71273:"+'5,#8.-0H)(+.(@*?);7&,*/<@(=*1/2%,$C?427EA<79G5AFC$2F6H'H*";&F5%/,6@#E6F/3@"/$'7$+3$*.<$F+
@r2358
TNATGGTGGCNTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGTTGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTT
+
($+##""*#!)''#'$*"+'$!'+&"*)&+$&')+%$&(%$!!(+)%!()#"!+&)%!'*#'&*!$'$%'&#!!%&*%+$!+$)$)#+'"!&"$(""$&"'#"$
@r2359
CGTNTTNCAGCANCNCNNAATCACCACAACCTGACCACCGTCCCC
+
#$($#(&(#("'(#("'"+)"#$+&$''(()$!*()&&%++)*!'
@r2360
AGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATNACCCTCGCAAACTTGTCA
+
2*'3:ABD-=F:@"5'5H/2&D-99%;"C?>&14DB#).7A/;6+B8D&@="%(A@,<5D%1:'=755+A%H1%46GH/:&D&AD>>#0$7AG;1#+-'B8C9%B#(>+D%A6(2G)A*&"B:@EG($F7F85;2+-*%<!(3G&&"C86:+,8,
@r2361
AGATTATCTCCGCTCTGGTTATCNGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTNATGTTGCTGCGCTCGATGCAAAATANACGAAGGCGTTAGC
+
!D4"1&?!3!:8D9;13*>9!/3@#"-6340@-"%A.:C7$*E&0?1=D21:F%1+>5)?"1F4A6)D15C5EG+!$6GF$C#*26H./5+71#01C=B"9@8'1B-;H?2"@-3,*?A"F;#?%)("?;;1D+-20BEHE?@H:>%G>?9G:0"><%)(52@!6F84F74-1;)3+4/1E0!:@@+86CE=7&009&>+;F
@r2362
GGCAGAAAATTCNGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACANCAGCGGAAC
+
=A91),A(*97D)078(E&A*!1B0:!';(;;0%FH%@<')%HE>GF&%2>$+*!159>7:$:,8F8:EG1
@r2363
GAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCGTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACA
+
1*+&7,)688C!0@E3*)45C!824,7D=H@>>;,$#?G;E$4::/)C3"$9+@84$>04/9E;%!++7"*193@1H612<3=2F,(DA4&E=#8::"6C.-?-
@r2364
TGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTNGCCTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCNGGTTCCCGTAAATCCTCCGGTTGCAAAATNGAATTTCGCCG
+
:#!/G"'**'<62/):A034E)!-F+2'*=/)H%CF'=&2AG"83+=4,$71G-/?H*;8-CDG1H5A#5,G,F$):A3H<;1+$F-:%:)FC=.<6#H0$57<;@/?%242*&G#?G@>,@B-65FD);9<:+&C#.+CA#,';7G-=;-#*/#499+6;)A44;!3$(;6+;(>E)2>
@r2365
GNAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTNCTTTATTT
+
%!$++'%*(('(&*'%*$+#$#*')++##*!('$$$"(&###)&(
@r2366
CCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTANGCAGTGACGGCAACGGC
+
";!?9HH*/6C-?=%..%=0:=&*'&,396+3(AA:HF!=F#7C&:A+<71B**7)5$*$7#<?/265-9+,HE
@r2367
GCCGCTNTCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTT
+
"!'$)''+*(+&$+!%!!&')((#)(%')$%$+#%*&$&(!)$#*'&)($'+%!*""'!'$%*&&&#
@r2368
GAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCA
+
4;6)(67(@>&FBHG4>5:2F3%:;H*?4,2:,&7'C.&7
@r2369
CCGNNATAGCANANTGNTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGAC
+
('*!&$**&&%!))#'!(&+(&"')&%$"&"'!()')(!!%(*)"%*"'%"'!')*'+"&!"(%'*%'#*$*%$$+'"%#$)%$
@r2370
CTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGC
+
-D02':&C,6.88"-$#8H2;B'!@F=4$H?(5?=+)+$<9$A7%7G%)0-4/";/+,G+2%2F5/:2+0(078E6$B0<6$@,>B@D7$'(5AE6:'&9,H!-),->8A:*92G%@2)$BGF"6)8
@r2371
CAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGC
+
C&.F!A@#>+,BBBH+>&!71AE</E:2,50.473:$2+00?1'GD#A70@-;!<BC;(;5$H
@r2372
GATAGTGGTGCTTCCGCTGACGATTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTC
+
=$!F,2'2@'5/+%+)'+5;5D"+AA$=C+6=:AGF3,>B&9=5.=8<*>C8.,787/-**B9G8&
@r2373
CAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATGTCANCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTNNTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGNTGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGNATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTANCAGCTATTCAGCGCCAGA
+
GGD?:/5&9>F$E%C:-7#&=F;.4:2C$;,C-$<,?A?"B>5*)-E57>5(726%F>>'6E#8)!3HH,9319,26523AB,;5BF/44<E)F:$)?*B*=$"&F8H$,*&D!A0**'-A?DD2>2D./',.&/<&FE9$9==*#C:D'8=;5.&8&17/"(4H-/(#5$!#81/FH8!H>/)@@0&&C2H6?8A6FCE+'DCE3-=:3++;E$A.4,;916)B!.#%98F.>D/?C!D!/3(-66#D>+.8&1AF"=:66GA:3=/.6C>/04F4,,82!+!6)FD0+&.>59((73<.HE-:G0H(46G*!$>?=H2;))2<H9"/$;-(=?=6@3<:H;#@%.>-6*658E%)561)8.=G6,()!"3!;$F.=7=B<%CGF"*$B**6D4G5,(<CFA9$%BD?&50*)EDB)=8EA-+42C$C7:3H/7?<C1*C-,.=-$2>*+
@r2374
AGACGNTGGGANGCGGCAATGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAANNGCCNATAGCGGTTTTATGTCACGCACACGGGCGATGA
+
))$))"!)'"#")%")'%!+!)"'%$)&$'$"$%#""&#+(%$+*#%'(+**""%)()&%)%%'&(()*!$!*%$+#*(&&$%#")((!&"%#+!)%"#(
@r2375
GATACTNACNCGNTTGTTTCGCTTATCNNACGCTTCGCTGCTAAAAAAGCCGGAGTCGAAGATGGTAGAA
+
)"&&##&#*!*)!)')#'()(*%)'&*""+#+&)!$$'!&!#+*)+(###'(+")")"((&&)*+&*&"#
@r2376
CTCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAA
+
!)'6!:(F'054<H,C#"9:==B6D(98F*$)G84;C6$8=2GF99,%.C)0?8''CEHD4:#CG
@r2377
ATATTTAGCTTTCTGCTTCCCTTTGGATAACCCACTGTTATTCATGTTGCATAGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTNCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTG
+
0*@-&0*AFB+#37.@=(D.&AB6@??7*)#/@G;8-8!.#(-&+6G$?6-&D%;%-/A,62(D(?3<;%GG0E/BF/&?+A+0?/5'"H?.3=26?-<@20%E=((!.7#>G0,()!&/C,@9C#ABE;<(,"H+@'5$"-B<23&A/.(5$)91CA?.=#6<&-G+$(+8$E5@+ABG"03))4;+H4")/#D1#
@r2378
CGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCT
+
6-*'>**5!"5(<1C-A)G7H;9(3.H")CC$B/A,B/#+BEC*4-#CB/:>5<.309H!3<8:-&?<$H
@r2379
GATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGNTGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGG
+
.65/%==A>:A:'&C)@-B.<8$DF6&-)D"+""&/C+("F#9E*F2BA$G=H@/4';@1&B@36?5>*/E2B?C3(6FA.C&6E%"AD8=7*4C674"!G=>!D1=96#':G<&5<A#GD1*B-?/(3<H17HD*5@0%.#?DF<3,1&/$92G".*.<A7BB!D:G=$)((=6$%AG$>.5383A)=)&+1;&/D&F#!H94H*/&B+6(.D@B4>;&<3.
@r2380
NAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCAGCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATC
+
+&)!&$&%#$*+&)!('!*'%%"%"!"$(*)%&(*++'(*+'&!!+$**')#&)$+')!$(%"!)'%('''"#+)*"(!&#"*)"!#)'$*'*"('$'&&+!$$%$+"!!!(&$(
@r2381
TNCCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAA
+
("&''-6:F.A-9/-,,/!.;"130.DC'*"$03B-H-?#;#./<58DD9/6B+D&B87+3;7
@r2382
CGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCT
+
A.BB'>$12';",+D6=F0GC8/+6>A6.>+4.'+#((1+GF(:G
@r2383
AGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACAACGTGTTAGAAAACGAT
+
6;G4!!"B(.'/#C,D.E'B"2.;457G!38+&%&6?(C7*7<#7F)8!#'@E0FH>$3<@#7.A@0;@)-C;CE2"3A$3B8.%8("!7?CC;39&*$*:G57=(4;3:G$?F*27E094--1+H-G!:;4:'5D?2E"@&@8!)"@10!7+$5!7'$$";5:
@r2384
ACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTNCAGCCATGAACGCTTATTACATTCAG
+
A;="D)=FE?F<>2(D:&5;8&8&7*+-6&5#F7'*-/!8!?:4D#BA6@#&*819!B98!)'1)%8HC57G4:&H<G?==(.AD8(.?(0:H/>.
@r2385
CTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAG
+
"'H.%/-:>!A&;6<$>6E/#="4>-*HA%4*)=31))&A)E-H>AD
@r2386
GGCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCA
+
*#0;=,/=;>39)+EAHF<+?-*A4E:0;E29%C0D3=@>
@r2387
AGTGAANTATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTG
+
3&+A+0;@%:8(?G8$E(1+5".$1"4'&+!;%'22)HG/(2;(5<,G1=4E43;1EG
@r2388
ANTAATGACTTTTCGCCAACGACATCTACTAATNTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTTGATATTGTCATAAAACAATTTAGTGAATTTATCNTCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTNTTCATATTTAGAAATGAGGCTGATNAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTNGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATTTAACCAATAA
+
)$0%CH*)!5*7#!1+E7/;-&?6'+>=-"%,4&"!/241.6'$8@0&F(?/C9HC+H%@?8+F<BD'<6:'>"22*>)FC/DD<1E9A'F8!:'0-<1'0@A/,$4:,>"+:>>($*,H*)58;-2B80$"'5>8@?3"<%C0E6?'&:.C6>*))06"?4*,'*$(@18G"E)'7-752"#>?H<F6<0?</2"746-=842+;$FAG2#E:?!GH%:'@46H=;'2"#1D4-+)HG%""H*4"@=1=78#")H--!9>B$7=@>H!.H8-#8CF491";9
@r2389
AAAGAGAGTCAGAANCCGTGGCCCGTGGTGAGTCGCTCATCATCGGACTTTTTGGCGAATGAAATT
+
G-CH$4=1G1B%F/<,7A:*H@%:*+@.-A4.@4%/5>)6&*=2D+/FF#=(!<1746><4.G05-
@r2390
GTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTATAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTNCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATNTCGGTGATACTTCGTCGCTGTCTCGNCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTG
+
1,F"78@E)<A3E,7FE5A4G!(<E/6-(GF2/%:*8379$,/<C50*4@F/<F)A1F0$@@<3:8&!9"%($6+2;E%62)6?4',&&*9E'8%,/"5F8F:H=50G26.&:321+5@:*4D(G8@@(&)?#4.-?50)/31><C!A+9&:3F<2<1DA;!"(?++C16+B/A01E'4,781HHGD<2E9"8+99=A:!/.))-#H5HH999"&*
@r2391
TCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTT
+
$3&45E@/6@(.=@;AG!"&E0'+HC+,=E25-F7B),*"17?9"=31C"G390#D%G*;;>#"@=DG."5#D&!D;?FF#/-6;C)E@82#E3/7<+7$!H"F19$36='D(H//66*,#.&(&).D=
@r2392
GCCCGCAGACACNTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCTGCCATC
+
!7!#9A0C%C2@;0F#,<F%4*GF*.@+184/;%D*4,"/C)5:;8HE7,)E.6/9"**6G=<+,-*F+;.$4$#@
@r2393
GCGTTTTTNGTTATGNATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAAT
+
BH-=#/:3>;##,A:%6D8B?$<0'8G*,.#"%1HB--8.E2=(+4(8G.);&3DG4!HH*71AB75D9BC*527C>!&GG$9+-,?7=;*.(8.@A8*
@r2394
AAGTTATGACGAAGAAGAACGGAAACGCCTTNAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCATCG
+
817*#1A"7A?20"9CD18-(.A488$%15/F.86G=*H,E&9!?E6!!?%-E1H3>=AB@21@6&421B1%E$$5:)74/*/1%#6
@r2395
CCTCCGTCATGGCACAGAGAANATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTNATG
+
/@$$/6+>.$/6=BF895+<**?.0B@?(<B(4,38?D=B=!E%H@E'95+31B$+D<:6A8#$E
@r2396
AACGTNNTNNATCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGC
+
#"**!("#$#&!%&+*#*'")&!!!&!+"'"#)&(**#%*$!%*!#$*#"
@r2397
TATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTTTGAAG
+
%)G%'%2?.+D(?,*0"%:6"F+1>FEA+6>E4D,(4>">>7<E;%57G0:H$F92>#.:@::5*<$B!=
@r2398
CGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTAATCATTCCAACGAGTGAATACACG
+
5>#C545D?6G=D:'%'D=D(/)-G,@,B11H/CFE!++25)CB>-!1#!:$>>H578@.$"*.A#!%<C2!84:$-?!73%&<-?(:(;;?)B4.'/)EA&("(#8=G5D)$)0>!2,988:)>=H4A&.)
@r2399
AGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCACCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTNTGATAAGCGA
+
.<AAGE2&1;08B@?5HF@/#"2(HB3@<6#8+0'A5:/C,3D@/>-./.(!-1#?9--!C8F7$2:H&6/52%=@?1.!G1%!;)!.!&19&08A?E2/=@GE#G%##<F=/0G'=?/9(,F0%3*-"#H3F+<-'8?.9*F:),?35';H5+2"@$B<-HE//34",!@>
@r2400
GGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTNCTCAATTGTTATCAGCTATGCGCCCACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGNCCAC
+
A?$%5CA$$G4/4**<*8@95@9>@?%C"#+0/(2>HF49/<$*C40+;:*;;->+7G/<7A-:>C98B4)C(3(-6EDA4,&1)#:CA?9=<%&4C"*=*G.*:A
@r2401
NATCGGCGCANCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAG
+
%@:##G">.+#.G!24;-,B9G$'!8;</.<4D*%AE#>?@2%:"
@r2402
NNTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTC
+
#".GF3D!H$.'8BG8:%@CA;E>;C<3&.'1+,5;3C.1(EAG;,F1">D+#-#
@r2403
TACNGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACA
+
83(E<:,8'@+6F<=4>1:4,5+(%;)*=@9@>3:A1?3#>!7<,7-:1(:+
@r2404
CCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTNTCGGTAAGGC
+
38@(;685&$F(@H9G+!GD=2-$-&)DDA%F-5.**&A;#G;#8D?)GH#)4C88&2!/@9C=@-C)C$D(2/A
@r2405
AGCCCCGCAGTTACTGGATTAAAAAAGCCCAACAAGCCGTA
+
*0H&-A#?F@"3!H1&*2C).(7A:/:91E0,$H4;-2;B$
@r2406
TATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGGAATGGCGATGACGCATCCTCA
+
ACA2B+H<37#<@<"@GC=:.5)-@@65624613D4@&/G5>?(.5H?$586*6.<8;C?:,&7*'(),C"*F"2:40B:E@@173@2B*51/21'''>;:?0A60&2-#=-<6):915"G*@"..*FGB>B=/!B
@r2407
CCGGTAAGGATTNCCCACGCCAATCCNGCTGGATGCNTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGT
+
(*(("&*!)$&%(+("+'$!'&#!)'%#')*&(**(*($$*"'&'(%%+)$!"*)%+)'""*+(!&'#)(*''%!(#*!'*&%*+(&($#!#!"*
@r2408
TAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATNACTGAACACTCNTCCGAGAATAACGAGTGGATCCATTTCTATACTCACCAAACTGTAGGGGTTGTA
+
A+@E0DC)G)8""AG!D$83=><B;8?59F.*<*)G:CB5$5:;*('!=/71(&BF=F:FC)8D"B@<2B@,1(?;5)H)".>(D$H/8%:-H5!&?6D8E:H,A#8%:1%5A@D"/+@@E8@3A<
@r2409
TGNGAGATGCATTCCGAGAGGCAATAGCTGAAGGCCATANAACAACAAACCATGTCGCTGCCACTCGCGCAGCA
+
")#*"+++*$*$*$(&*"&%%&'!!&(!!$+%&!#&+&')!!&(#"$&)+!%'%(*%+&$$*#+*($*&""%$"
@r2410
GNACGNTCATCATCTGACACTACAGACTCTGGCATCGCTGTGANGACGANGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGA
+
$'&#)!$*'&+'+$#(*!#%$)'#'%+('*"%$"#('"'*&+&$*($**'%'%)!)+&+&!&$(!!($&#'!*)*"*$"!%++*!'(%)"$$$%"($#)+**#!)#!*(#+#*"*&&#*)''+("'*')
@r2411
GATNNGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATGN
+
#*&'*$$&(+$+%&+)#)"$)#'))()(')''*+"#("#%*$(%'*'%)%((+%$!#"%"$*%)+$+'$
@r2412
GGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGNTGCGAAAAGCCGGGGGCTGACTGACNGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCNGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGG
+
$)5<6@&*-8+B=:,13B+B?C:8F:H<&<9"/7)(??93=7$=(H1<='2-CF>14-*2=6:%8C1C6&EA47>>"(+-;-2?%C56(?,!&,87D;>G9+E)<"/7*9?#64A3CF-&,5)C,9=;.E0"#,!1("!G/+F"E=6*%.*:21F@1@C%<FD-CC;.H::/E2F?)$:>!92H)AF@&=2(00!7%D45*:4
@r2413
CGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTNCTATTTCTGATGCTGAATCAATGATGTCTGCTATCTTTCATTAATCCCTGAANTGTTGGTTA
+
E8#'D5#-3/3%D*H3>7EHB(&6*#3"<&=A$AD1>G*:H!77+H.@D6>B)1F18E"=H8"0*E.;?>&E&<$?1'D9E<?/H4FC:-)/@)2?*
@r2414
NNANCNCGTGCCTTTTCCCNCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGNCTGCTGNTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATG
+
#$&"*!&$(#"($#$#*%&++&!%'++()"))$'%''*'(*!"+*!+$!%(')#*$"+'&*"($)&'%((!#"&(+*$&(""('$*'$)(#!''*+*'"#+$+))
@r2415
GCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACT
+
?,8B!%-.#/G!?%32E4DH2@7#D567E8,/=H<")68D%D,;22'H:?=-EE2?>9
@r2416
ATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTNCGATTTAATGAACGCAATATTCAC
+
G;(&+#+".@:$96$G1D,6*29?-$9BE-?F"C12<&3+!#!5!+/))=*1:38,F=C(A?61.0+4!4:2/"/'/'C*5%E3+6H;C'"B;C89E:C
@r2417
NCCNNCTGGCCCNATANGGNNNGGNTNGNTGGGCGTTTTCATACATAANATCCTGCNGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAAT
+
!&)#')%#*%*$!('$)%%!*!$(!$%&")*+'''*&"'&**$##"$&%!##&$)!)#"'&+!%!#'"(*(!"%)'$*$+%)$"#+$!"'#!'%&*#!($()"!!+%
@r2418
TCTCCCTGCGGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGA
+
7,7,#D%%?-DDE98$&6+C7$6-*!'8<DE)HC,+=7.;0;80,566A92><C?">C1.HCF@F*E=,7?C6EG2517849A-'+;*=>D#)1
@r2419
TTGTAAACGCACCNCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGNAATAAGGT
+
*-1&4,$7@13#<).5%(8&196GFB?<E@6).2*"#*6,@;+$*A>&(7*G3=4+*07H:904#'/C+&/D#@;B&33D8>A3:.=,A(C6>A6@:)CG=C67!3$%)"4/ABG>6G4,"F&6-'2'B<5"D>=>8$@4-:,C-9B)(B@>32!78->#$+(<9<A(2&C8.E0
@r2420
NGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGC
+
#<8;$)=:D?F65'>#-!A%'6A?)4,7<;HH'",$?1&48F/3E.
@r2421
NGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGC
+
#/2&F=#?*!.B+AG%=A-:'@#-(+!08B=.*5E:FF)&D0!"5#4G:;$G6@0<!,0.BF/%(FG2*4G667274
@r2422
TTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGNCTGTTTTTACAAAATCCGGTA
+
56(5E2)>7A+-(+D*3@%D<+%5:52)DC3G-60*+"9F#5(.B.;D5$5E"071*H&2-H7:B9A.0:#(8HF142$:C&@'$53D5,B$0%(HA0+,226H@$3
@r2423
ACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGT
+
C=?#4;*4)BB$#DC2>A:"."/H%03#293+#"F2*;'#'#'>F6),"*$-0'/1E!+>0B>*/*>'#FDH?1'';8+A
@r2424
TGTTCCGCTGGTCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCG
+
*(9-B#86C.@1(16C+-5<3?9+*%C3+"*./7,82%/>#D88"/B=94E"A
@r2425
GCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGA
+
7,H:2?:!F>,#9$3"E*1,5(GE3A+3C/H8=%?G:/#B&6
@r2426
CTGATAGAAGCCGGACTGAGTACCTACGAGAAAGNGTGCGCAAAACGCGGTGACGACTATCAGGAANTTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAANCCGCCCGCCTGGGCGGC
+
0GG67D00/E$0-?+3EF<E?;#2(=03.8%&8-F';,3?<F::8)B.1.%@AG8,:;8FGD#0/HE->?@50**BH'$./6.24@#'$=78*G0%(@A,87&@3@/?+"6B1%#:0<4*<4>3/"%*E$3A-$514
@r2427
CANTGTNGANAACTTCCGCCATCATNCGGCGAAACCCGATCTACCCAGAAATTTTCCTC
+
'#"%(!+$&%&+#&"&%"$(+*(!!#"((%%%#"+$*)##(*%#"()(('+*!'%+))"
@r2428
GAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCG
+
(@/C07B>B:)2"->E@($&0=.C-=!),C$:DA)(29H40!4)AG&7=>#3C"/AC47?D&)/8F#
@r2429
GGTAAGCACGAACTCAGCCAGCACGACAAACAAAAGGCTATCAACTATCTGATGNAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTCCAAGTGCTCGCAACATT
+
EE29>5,!9#;>#1-B0E449BCB.'<@%6-)D#A%A.)&47/A09EED>"&8'05,75/E-%?EG!9=?:,FE8(7G5FE3(@>7,3B/"-B7>'::;CH>%(G02<.20#5.D/==;':C;$B0.*-*,.(H?HG/24E7!$)3
@r2430
CGGCGGAGTCTGCTCCTGCTCACCAGCCCGNAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCACCACGCTTGTTAAGCCATCCACCGGACCTTCAATNGGCCC
+
3=?%;@-;C=?>>+;;ECE"%$D1:@D!)":<7'5.#7><;;&<$,=%1:(#$1@0F4)@HE3+E@H"=H%#:?:B2;;=<)F!"H6@(-:7!,)?/1/H2:42-;/B(&;C!"E)";1*)!$<6@3*GG*!@0"F,C
@r2431
GCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGNCGGTCAGCATCGCCGCCATA
+
,+>B#D&1*)>!"<#8F1-+>7DG*8H$6?,8C<+E>(/6-"=A-%?E<>F6D4,/%H2<,#:5</#0E/5@=F"@B>/=!3>77'>,%CC<8
@r2432
ATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTC
+
>0&>"?5GD346FG=G*(//;B%%@.B==B8=G<A*&$F!*?H11<@H7,F'!;C''%)A46:0@G@GE5">3;(9@35-+@A*?&F&FD6*B.9C&-&0".B9=6%$+<
@r2433
GCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACAT
+
H8%!://&&07>B?1:!7)3?.A?5*E5&05!%3A.!!@0F?0,!2$#11F%")%F-%)'"*=DA&,A(H.'@>4.$")//D81CE3C(.1&8/3+8B,4.)'6%8-"8352!A2$8G<0-,$):E/7!?58!7#""%6)-".<3;9+H1+@AB)"/H.?3$#GG(0(;*&13);B'F@C$4#-FG3(?#62.
@r2434
AATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCT
+
/(;*A(<A,2".HG#79G##),-*%G&3&)08%%E?E0-C/H/2085GB@1!=6G#A85C#"030=)F%:)H
@r2435
GCAAACNGAAATCACGAGTAGAAAGCGCACTAANTCCGATAGACCTTACAGTG
+
'%($#*+$!)'"#!%((*%$!$#)&(*!+%&)(%&!#$+*&+)!*)*$)(+'#
@r2436
CTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGNACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAAT
+
4&+<.@'!,A:5<'?136+D4BC0E6!+<+B@@-H.)6$!$)6G.;/,8G$+&?@D?>(9HCDFD!5:B#;+#<G!9;DF%!10*+&%9@H<F14>&5%%C*+B?5A8D:EE32???,1E+(3B9D:G<@")4:9A7?"@'#!&+!5A06A/":&8>+'DF*B9%#E3
@r2437
TCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGA
+
,'>F0.-$<#=2B<-->G:,:4H;E<4><2G596..<=F+5,DC5,H06
@r2438
AAAAAAGACCTTCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACG
+
:32E*442DG&,(+/$9F.@EA2!@3C9779-.&:)07.'(1!19?6+1=H60=@
@r2439
CTTCNCTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCC
+
"+!!"''%$(!)!(%%('%$#%&#$")!!!&#&!*'&!&!$(!%+#%"*(#$"
@r2440
ATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCNTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGNACCGCCATAATGCCGTTGAGGTGAACTGGAGT
+
C&.#8;5=72E21##FA=C8H7"):9)8B@=*,?()@E6677H.F?2G(()B:H2&(1E39G94C'645/'7:3?,H$#@+/:<4<1@0%/&(.09G,/.0H+2DC=@,*#F(&2>+E,!@3,%G=!A$C/>44C;23%B)!77!8:##&@*+$1B=*5>
@r2441
CTGAAGCCTTCGGGAAGCTGACCACAGACCCGANGTCGGGGCTGACGGCGATGGCTCGCNAGTTCCNTAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCNGCGATGAAGCCGGGGCATTG
+
;$558>BB3)CE>H!)E:52#FA6<496EF7B46*!"@B:#@;,5'<'31&A8=0A1.EB31<1=8496;0C$%67H>)E64%E)H-46C*$#?5B8A?E%C/%22?73FC978B#++0)F503*718?2?AB-?4%
@r2442
GGAANNNNACANGATAGATACGCGACAGCAAGTTTTGGGTAGGCTGNTT
+
('&)!'"!&'"%#$(+"!+*)+"+'+)'&!(()!$'('#&)!%('%%$%
@r2443
CGNACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGC
+
)&"/0&&E)4#.+4#53C/?*C)"@CH4>B;A3>6E)'?>6-0:B'*.!A'A
@r2444
TTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCNAGAGGGTGTGTC
+
)%.181>A,F&78&D?-?4!22$>&#,,9774DH1)?=#4?"?'<3%?-@?6F9
@r2445
AGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTG
+
H;3E"&!1;1)37B@,B%"AG'A+.-(*,4'2.:(0A6H(D5!+8D6?B0D6$5E=E(B&-+%$412DD)&.&-65,2::GB'A:A:/+;6=B?A2"&/B9-@+GA9)H>;:$'0C%!)#!G%#.*58&"1'
@r2446
TGAAAGCGGATTCGCGTANGGGTCCCGCTNCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCANCGGC
+
+4(/$5E13)'F3!B>#+"G<',2>,;;A/"?4!705>:!.);!92)<"-21H+6@1#)B*81-834*"4/;
@r2447
GTTCANTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGG
+
)3&"BC#?"756++(/!#<;?H=3<!.560B)2C:=;&4:-4
@r2448
GCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTNTGGGACAGCAA
+
&G#>;,:2"6GB5+3=<&BF>@>"903!-G+?(!F4FA'22$#0*2HH)/7>>-45#C=.7-'>+(@8#0$7(-"7@1H/AE,<<AH?6B+5+'$&CC:*&E%&@C@5+983"9:(-EGE;7'F*;#C"?D8!<,)!-%$,(3:H!&
@r2449
TACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAG
+
@"H--A1'E?1:)").((H9?@6)173"@B2C(9B40$#G>"&2(53D-+.G-."H1/34
@r2450
TTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCT
+
.G=73/DH<</H!),)5HD2D!+)+/D<+B50;:<0(,,,)"E#@?-.;+>:*,8&9G>,-4D>G$/F8!:*'E;"
@r2451
NCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTACGATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGNCGATGAAATGCATA
+
#+,E0E4&)940/&3B',?H;7HG+4(B"4H'4>C<@CF2A@(80'39,CD:6:/BHC(*G%%++&/.18B$(DD'0DDFFF+4G&A*3F<8G9@&+*@&F11/;?H64%48:4*8
@r2452
TCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTAACGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGT
+
(*7H;8B)C.E?;H3<6">H+15B,+34><./;D1=A=3+2(+)+5&B,F",0#G6*A48"@FD9*7H$G&61E6%G-7<:4>=#'+76>(,A/3%)=,*C?),,03!?!"B)9'E8*$=/.GDE2E+;!
@r2453
CCGTTCGTACGCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTT
+
*#<%986"!*7D*$?3?&9*E;*!!4*$*<=#>BH,>+"$?=0C1H18;!:=%'F23-?
@r2454
GCCCGGACTGTCAGCCTGTATTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACAGNCAGA
+
#?HD8$<255:&1.:(>970!@D8)(!9'8#!F/$3@61D<;:+<E3B;;><@#!-'@'28.F)+0C@H%1*9H@96<A%@47,9!&H&+0$.8F1?5$,>"'6;)DH23C080*"#
@r2455
NGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGG
+
*9F46E7A-&,AA:$B!1&3>'78(3$82,A+B1<6G+@0+B/)2F5$F('16#C@22A$=2.!@&4619'E*43&<'7#%80=G9?@0*B*37.6.0)'(*;':CE)A->A9:
@r2456
CCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTAT
+
B386--9@C+.=F$,0<C.G1=5E?"+A@-'2(G96E:E6D030'1?0*6-D;'0>!1B:B9G&$9>B*)*FA%D,(,$AC'D!@&'>:/D3$;8G?4)+9#.7B4)E(D"'E:)@'A'0!1:75D>"-C4C0<G;6AF'9#2(2,@*3:H%*;@7!56//#$>35,;F(-H->8+3<$<;%F.19$2B:A0$95%&@,,F*C:21FF?C#B#,$00.7?=8D"C3E$".&<=353D=C$;"#C$,/7H:C@
@r2457
TCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACT
+
8@(7@!):7!8DF2C/99B<9B?&/"376='GD>C!D+(>22!97$'.'
@r2458
AAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTT
+
A@01$.#&=A:%7E#2?.*!1F0;4=-H%E84/6A>+4E-;C4"$8B52*,;H#9?;&3)>B@)&0@GH?B7>;C#G!DE*,(B=',:*:<:.&A3EG4?4;9FG1H<G9':+0/&H6>-*'H#0"@3*%(9?4F9'="!&,D<"639(=!70B5&FB6?E+9'2)"B/><3B%2'819930D/C
@r2459
AGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAACATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCNGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCA
+
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
@r2460
CNNNGNCGGGCGGCTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGT
+
*!!$+('$&"!"&%'#*#"''('$(+)(+&%(+&$((+''!+)(*!++%+$$$**+"&'&'")(+'#**"+**+!"!#
@r2461
NNNNNGCNNNNCGNNNCCTNNANTTNNGCNNAACAGCCAANACANNGCCNCAGNTNTNAGNTNNNANTGTCNTNNNGNNNANNTNTCATGNGNGNCNTCCNNNACNNNCNGGNNGAN
+
"!##!#$#$!!"!!"!""!$$$"$!!"!#!!#"$$!$#"$#!#"$$$"$!#!"##!$"#!!""!!"#"$"$$!#"$$#$#$#$""$$"#!!#!$#$!##$$"!"!$!!$"""!$$$!
@r2462
CAGAACACTACACAAATCTTTCCANGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCAT
+
D+(8;7&3!D9$E,F='H6)!!9B0FA<"43"@!.-%5A;7=##G(C&$(-#%<?<%B!'2*#C*.8;@CG;3-+$
@r2463
AAACTCGGAAGATTTTTTCAGAGGGATNTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACA
+
++*(#!$&)*"'+)(($)#*##!)$"(!&*#)+$''+%%&%&%"!+'&&%$$(+!*!*)+!"*#(%(*%)*"!*!#&'(#"'&"$(&#)"$)!**!##'(#%)%&$'(')%$#*+'"!&"!*+*#!"&+*$')+$&#(((%!"*#!!("*"%)"!)%#"&
@r2464
GCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATNCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGC
+
*DD9B5E=!<=H1EF(F;60?4?6#F==#?+%:!1H"*F,,F$2.A>*$"D:&24(>DD;"*%"#,F*':06%C!/4%7F0?7D94;6%!-$=(/1(C&6=-***
@r2465
GGATATTAAACGGGCGCGGCGGCAGGTTAGCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCAC
+
/E@46,9=7A906+H"=7,516@/$"A$$(D)%B&E*G4<D"D.C-71.G4@F5$)''%$683?@321(,)=%F"#>;*'=%82(*7".D)1#=;9G6!(:6DH?
@r2466
TATGATTGATCGTGGTGACATCCGTCAGGCNATCGACCGTTGCAGCANTATCTGGGCTTCACTGCCGGGCGCTGAAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGA
+
D%$9:2;E$.@<'+4>36$<B,5$8+&'<C/D.C'+3/C<D%9E1FG<4?=F-&%127A.E1)$@."&***<F2!&D0@9<)C&55=2!6<;/B7&+F"G>*-;8"70%CC4E#=36.2!5EB,31+?
@r2467
TCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTG
+
&'C@FF,'!&(!!<+7-:B/9B8B54;.6)@)*62HHA8@F5'6,4:1@;7G,,4C$-=1;"!G6$0'B3F=+%9"(5GE(+8CF+EF3G,!+$+4)>1@=;)&,H;!"%E%4H=$!42"A2
@r2468
GTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAAT
+
7%311)44:>$%(222C11().C#BHE$.,4E"$1@)385,:A370H%0$%@'"11D/91H5AH(-/(2D4'EF-'1>0.E&;)B)=24B@$(*:>
@r2469
TACTGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAACNAACTGGATACNATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCANAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCAGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCNGAGNGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTT
+
'("'$)+$"!'#$("#%!+!%)%'$*"%#$#!(!!)(%+)&%*$($&%'$&"%%(*(%)#'#!!+#+"#')&%!!)""()+(%*$'))%*%##"&*#''&*"#$'("!*)')%#('&($*!+"#&*'#&##)$%)&""*)!(*+!&*'!$+($""#(%+*!))%"()%*$'##(!#"#+*#%%$%+&"'&(*!"$!$!+*)%$&)+$("%(&"$#'(!&($&'%$"!(("('#%&#'%!(""$*($#+%&&"&+%$'($"#&$&)("%&
@r2470
AAGCAGATGAACTTCCGTCAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCNATTATCCCTTTGACGAATACGAGTTTGGAAAGCNAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGG
+
E##"C'B:4$1*6>$D'7-;C'-"3D>,?ED*F3>4!7FE68-"H;8F.!05:&&3&H!82;A1':38+%+F65A"@%5A30(/,A&C>$!;4"D'.'->4(-*;-D3=;1.>EE#0<>-E7:=#H=1(2C$/:(H*$**H;;@&G:/HE3>9%<E9'EC,G)DEE26;"G41#DF>=GG=E+':5
@r2471
ATACGATAGAAAAACAAGGCGATTTAGAAATGTANAGCGAGGCAAA
+
EA@A(1?5!(F='2BBC%6"9&B$G@(6#:=;1B1D<B</H<&5%*
@r2472
AAGGGGNTACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCNCAGCTGGACCGCTACGAAATGCGCGAATGGGGATGGGGGCGGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCANGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCC
+
)@<.)G*&>09*:>0+#'C=AC('HG+)#8D5=5!CD.FB+;E?EBH*1*A$<,B<"#08/D'3FGB.0(;E(A-5)823CH(C49)./F)83C5<A2G:5(/'#&&5@,4>C"5D#B<&?$<-)A$@7!+2E>,#=D:)0AAA>?:&3+4#=:,--)0H;%,3A9B70H=G:0B2A1:;'+#G7&!47EA&2E759+5DD459-@<@=<:8*F?H>*80/#47$8(FG9;B#%+5%852+C*0(2D:<<(DB%<49%"=43=4,/&+3;=D/*=6#-F+!,50086,>E,B&
@r2473
ACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGA
+
7%<;$H<F'1-4E;F@>'5?)?$:*@G/4=)95C?(,+/-:(2(8CC
@r2474
NTGCTCCAACGATGAATCCGTCAGTACGCCAGTNGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGATGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCNCTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGACATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTNCTGCTCTTTTTCGACTCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTNCAGATGACTCACACCGGTATCCCCGCCTGACAACGACGGCAATGTACCCNGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTNACTGTCCCCGCA
+
%#!($*$+#!(!+()!%"$$**'%!%)'('$'!&&'#'''("&&("("!!"%$+)"+*&&#!"!%"$)&!!+(*)&%+%"&&+'$!$*!"()*)&'*%*'!%#%)$"'!"&#*+)(*&#*$#!%*()"'$))+%!++++#+")$*)!)!(+')(+&&(!%%&#%)$)&')$'$$)&"$+*"*)%&*%%)+"&)'#))*(*"+$%$*$#*+!"%!!"$**&$%$"(+)+)*+)$('#'*(&)'***")'')#&+!!+!+%'%*%+"%$)&!(*()$#'#('$!'#'$"(#(*)$"#!#++%$&!!%++%)"+&$%$#%#+"$***"&+)#*&'#+##+("%%$)&)+$)#&#*!'+""!+!$&*+)&)!$"('%+)&'&$%*!&(+*"$#'""**'#")!"!!"+"#(((#"!((#$#%$+)('&#&$$%+*"!#$##&$+((%#*"'#++*')%&%($"'((+*#*!"$!!%&#"!!&"+()'"&+$)%'&%+$"*((#)!''"(%$"#'(##%)'%"&%)$(*)!+!'$#"$%"+#!!%+!%#)"&$%##&(!%$$!("')$)&)
@r2475
CCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAANTTCATGATAATGTGTAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCA
+
*,;5)F8F%22+'*H&=%439!)2H!"'+F>F*"BD-H(B08((&!-"G'9,H?#D1E((-!><CAH?;CGB?H@$:3B.)(2*=*HE=/28+639%?,$=5,3$&F4E#G>G7/3+((*C%'D((@B&C#
@r2476
TCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTAT
+
A":G<6'0F<98#7"%'>63G2G?1&">>G+,#70*0#;$(G
@r2477
AANACAAACCCGCNAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAG
+
@F#;0.G-+(E1D;?:!D+A8=20.0%G0'/2C$#?.9/>5&($G)".*:0E;47))@E#C=>2="4#=1-5;67*?;*78(#$A&,/@/7?A87D
@r2478
GTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTACCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTG
+
+)%&(+&)"(+'*"&'+&%"*'()%&+$$'*)##!('(*&&'&'#&++#+'(*"!#'&$&&+#!+(&'#&""+&+*"!"&"**'+#*&#*(&*$!$'"%%!'$#(%&%)''()&(*+$+'&!)+(+$**'")*#*&%%&"'+&(&'*#()+!%#&)!&*%%"&"'%%&(!(##("$"++'#+$"*!'#%(#"*"&
@r2479
TNNTTNCAGNCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCAGTCCGGCCATGGCGTACNCACTGACCTGCTTACTGATTTGTAAAACNGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGCAACGTATCCTCNCCGGTCATCACTGTGC
+
(*$%*##$)#)+!"$*"&!#%&)&*(!*()"*+%"+'%&!"%(!*#$!"#+'"(+%!!!(#!$*!&%+'(%!&(!(&$'!*(&"#'%!($+"")!&#)$*++)!)#()#&%'!'$##)&$#"$#&*+)'"%+#''+$#'#$%#$$)'))$%(#(+&""%*&*'!!"(*$")"!(!!%
@r2480
CGGCGGNGATTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCNGCCAG
+
&$&*''"")%%(&+#'#)&#%!***#(##%##!%$#%(%!$)'"+&)#'%'*%(!#')(')'%#%('!#%%$$%+!"!(($&$+
@r2481
TANAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCNTCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATACGGTTCGTGCAAACAA
+
;G"*('D@EHCD2%,!,45C=B=D2H48D,/0/,$G.$F=+H?3FB-B'56''H':(E167)><=%86H""'".@@/=)04A6-G@27;4?).H6E*07G+2-)+?:7A:E49.)<(,1/F*<9C40BC5#C',0/B924<+*!'9G!+D07D%,5,>%!&=C8<!;6#A8A%5:-9B
@r2482
GAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGAT
+
=%B;C@G(G8$2=&-+=84<<-&7HB<>0!--"-"5)($3E*B:B%%!31+<67$-/G8@&C&@)#%%1
@r2483
GCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCANATTAATTGCTAGCGAAAATGCAAGAGC
+
)&+)%(**&''"$')!##&$##+#''&!*#$%"+"$)$)!!&&#)+$)(+)%+'#'*#(!&"$$*(((&$(&(+*&&"$&"(&"$
@r2484
GNAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGCATTATTACTATGTAAACACCAGGCATGATTCTGTTCC
+
$'*+)%##+&!)&)"!!(&)!$+&#$+$(+'%%**%#(!&')+*%+#**($%")&"*()')(+&!)#!*'&%$%)!+)*(&*#!&)#%
@r2485
CCGAATACCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGANTGGAG
+
,A*38-@27!32(A8C9A7@>5F$;-9E8),?D?,8AB#%'D"<+A-#B=@DE#$C64H&!;(+3G8(=1(
@r2486
AAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAATGTACTGCAATTGCTCGCAACATT
+
8=$1;&.73'.")H43,BHE?2"D@:H6+2,H>G/$;-6.4/..E"=:;*6++C!*89*C>B8A6+-9"/2B?#H.33-.*#1)>(>D*E1<0?;H;6,$&2G""91&;=,>8/<
@r2487
TCTNCCACAAANNTCNACGNGATACCCACTATAGCCATCGGCATTGCCTATGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTNTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTTAACATAGCAATTCAGATCTCTCACCNANCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAANTATCTCTGGCGG
+
)&$&'!!""(&!!%'!))"'%)+'"%!&#$**+"%"('!)$&*$)')+'#+"('*()#"%&$+*$!*)((+"$#$!"')!$""#*!$&*&#''"%#+'&%!&#%&')'+)$$#"%'%'"&+$#(('$*#*'*(+")*&&+)%&"*)"'$+*&(*(#!'&)*((&'!!(!!(*%'$"+(&"#*$*)((#+'!&""!*")&#+$!")%%((#)++(+"&)#()"+)$!)&$#$('*('%"**&*")'$*")$*'*&%&#"#&$&)"%*!%!)%(%$&*"$""#*%&"(#%)&&%!%+&!*!*%*)*!"!+#")+*$)"(%##"!
@r2488
ATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTC
+
29F:,@?#6;=A=!9/*#=9!@!H=E!:=:#(4,8%>7+H32;H'F6G?=H9=9+;<#@3A"9?#5;)91BE@F#79&,DA@3.%78B%&-2>4E!.@F;D>")-33+/<1
@r2489
GGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATGGCAATCACTGAAGCTATACAGGCCAACATTGNGTTATTTTCAGGACACAAACACAAGCCTCTNACAGCGAG
+
,$"*/03H<1A!2/H."-*)B5'9%E293'>'G'2F1H9A<=>*#;G,=1A8D280"@433$,5=5$G#"!0@$2<)4"3&#?/=&4DA&GH4@<:(+3;+2,6-#CAC7F/691F<6C2G
@r2490
CCGGGCTGGGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGNCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTGCATANCGAGCAGAATGCCGTCNACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGG
+
&)'($$$)"$)+'"!''&))%#'#!)#)!"++*$+$%&#&#+"%+$*)&!$&(*!)&+!')&!+)!%#((&&("#&**$$&&###*''"%!&#(*)()%((!%'!##%"%$)%#")$(!$'#!$%$+*)&#*!$"*+***$%&!#$$)+$%(&"+###"')"+#&+*#'!%)#(%**$)+&'$+#*&%''("%''&*$'")++'%&+"%)&&'$)("%$(&#)(+(&)+*#(&#*!%"*+&)"*%&'%$*%)(+
@r2491
GGCCGCCACTTCAGCTCGAGATGCGGTGGCCTCAAAAGAGGCAGCA
+
B'4@'.?#.060)7/&@HF1B2E&,!!*+A2G%(AB)2EE;FD#%-
@r2492
TGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGTTCCAGT
+
*'+('")"!#"##!"*($!$")$$%'$'"$+(!(+($)&$#)+))')+""
@r2493
GTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCNAAGCGGAGATCGCCTAGTG
+
%2?>-@'=HF-#19GG5)'/F4<'>.!E6((<H&DC0-0D;4C6F;,#5ABDA>*?0'D:%?1<8+,.$E;/;8@:)#*7/*2(H46:3/:30>*C?=1AF-6,>8#C>8H74B=8!C=H'#>9-9+3@
@r2494
TTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGANTAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCNATGCTTTCACCTAAGGAAAAAAACATTTCAGGCAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTC
+
@<H3@C*2&$<;H(=E.<-<;>A377?&D+<E-);%':.1'.0>D&*,83;&"+:"5+$;62G1.0C#%,8G@EE<HF?$52F#(,)+-B.%3,=-"C%1,+451&#=@,B6".2<D8'C$H?7A:GF;=A&5(#"$#:@G,<E3=.$D:34:H)C0"?9)E=8.-&78')C88;1326(-B>%?/?:1;1;>(&=-/1+!/B+@8.D827:&6,2%07<72G;,*@&A(!1+C0B,":+?$,"+"3$0$C3EBC4#(4&6D)CF?H/<CA
@r2495
TTTAATCAGGGCGAGATGCTCAATGCGCTGCGGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACNGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATNACCGGATACAACCGGAATGTTGACCTTGCNTGCAGCAACGCCGTTCACGGTGATGGTCNTACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAG
+
67.$3<'!1;(5B7,H=-H$3&D8+)=8/98#??,&EC3C<AA.H!*B/63G7D0)%:;)9#:?G11"-F!@,?1/>+(B+5GF*2.4%"1(<<=5)?;C&.063(.@</%A9<+2>6!<@E=DGF:#G#A4G+HHAA#E1623BF4(E<%B;4+<AC0DDD?<5<''=94")$+,.BC.D59)C#?:19H*4>FA#?BF2#"/,+)4B7$&0D6<6:;-3*;?/E8#A%7:EC(,G9GB;H46$@+0/9!&$"=":6%#2&,.+H762H42>4
@r2496
AGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCA
+
4(G'=>@7(7G00F&6(A10;0;06((4&=:!@/BG%1@)#9)"B1?$&A+$D862$,<'489.F$=B?10B6B'#E+H.B%#4(H$<=H&//E6."(,A>!G86#
@r2497
GCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGC
+
&@%8G+#FGG23-*/3@8)E+=E'(/)#B=A5591?5?#,7-$C24*C@3;):"#F)CA-?"5A<$<3();)/DD;C:!=*H+%F!0@"7@;F2??,*4-<"BB
@r2498
CGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCC
+
A9EAA.1,03-:>@-48+"/:%CC':3%GC(+F%C"46D,C)'!7.5&@0H'+1:<26@9>2+F+%F"/?9;?*"E5/CHA")21$'GG-6C:&:0&5;('5D,#(/?@!3<-A>GB)*+*68"!(8E<?E6=:B/;*GFF3#8=3+HF;9?B;(B#!#?,,
@r2499
GAGGATGCNNTGTACAGCGGTCAGGAGGCCATCGATGCCGGACTGNCTGATGAACTTGTTAACA
+
%*')"#'%)#+++&"))"(&#%'"%&%$)%'(!"&((#&'$$*&'))'''*+&(!+*$)%%(''
@r2500
GCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGNCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCG
+
'2E+:'(.6E0FF64-9/B-;71C&:$-1"6<E.0'?-"+662%?-,'-*),?1HA1-:CA>F7*:+.0$D:@.F-G3%C&*G$&,8B-GG1#4*5?#/4@563-<%?"98%/C!*=/@B$;CG6E24=$0)/>92FAG%!3H
@r2501
CCNNNTNNGTANACAGNAGGGANATNTNCACANGTNNNGNTAGTNGNTNG
+
###!$#"$#$$"$$"$"!$#"""##"!$$#!!"!##""$""##$!#!"#$
@r2502
TTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGA
+
%"/:'5%F8<5?,/@93D>!98--9"D'6B348&;ED0*:D4":B.<3/$5(,>:E'6)68:5C5-88&"8G1='%)!79<8;6-&+=*7&D;!'
@r2503
AAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGANGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCAC
+
?@*E1%A,':G0*-F;??/#(?6$A"2+(A922:(($E&*A9BG*D<<%+C0>#>.><+9,""A%)"A$4DF7(9838+%?;,!-73D.,1C)+<+*3960D9DC&0',D@;7<->.0G/&-4!E8-A.<9$CA;05
@r2504
CATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGNCGAG
+
:<(),.,E(8>F8+C1(=">'=01)H@5'G?@/6#(3G0H&B<D+!@4D//
@r2505
ACGGCTCGGCNTCATCACCGCTTCAGNAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCC
+
;$8+0;0".8*A<(4A9:&5BAC//=,??>:7&-:"+49F"6*-<GC'6C0-42!H(>.BG9DC/""'EC-C=81?A53E7%@2=$0E@C8%&9'
@r2506
CGTGAGTATCCGTGAGAACGACGACGGCACGTATGACATCACCGCCGTGCAGCATGTGCCGGAAANAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTG
+
.FC<>G@BE%#)&)#:H'!,01<+B0.A,FB/H56?75((7C+051C:=><F<91*3+5+@)/6<%:.;7/BGD4C'=@G-FE:7A06F(D#E;8)<;12*HC-089/FH/#0C5F:H#6;$-7&;+E
@r2507
CCTGGCAGTGGTCGTCTCTTTCATATACNCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTG
+
'>&&DF4>-+51!)D%0/EB2G9(+(</3FG,*D)1#2F<:F*/1)B90'H76"F"$H;5G'36A6<D;'*/(>E?)."/B%#'88">,2-5C*G(6<#A+CH5EG9FH+B;!"*(:
@r2508
CTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCNT
+
-G6>>H0G403DF(16!D1)):E99;3=96@@-84)E&?A$8017/@+E;A0A5)?9+8@E#>@7)'*=24$@2#
@r2509
GTAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGC
+
&9=<C92,;'49<;=(D70(-6C%=)9(7(62137D18%%'-%,
@r2510
TTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTNATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGAC
+
5:9H,;8(46?32400$%"$*F+"D@ED5?-$-.(EBA(@<0+*+A0;69B<(-9=C(3922.#,"6F&F>H(6!292"6%/5<)+!*!FC;62:9D
@r2511
NCTGNAATTAGNNNCANNNATAANNGTNGGNNGGNACATCGNNNNNNNNNTTACNTNNNNTTCNTTNNANG
+
##""""###"$#!#"#!"###"##"#""$$"##$#$!#""!""!"""!#!##"$$!"#$#$$#!$!!#$"!
@r2512
TNAAGGGTAAAGTTAAACGATGCNGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTAGTCGCTGGCAGC
+
*&C1FB*;5'53A#G":>@&"A84:64:+-(*0G-?36D51G))>G'C)A:#/F*FGG0-'(G52A./-#B!<92
@r2513
ATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGT
+
$G+:.*0'>#F.&8A=&'G@(.9(9%6A@D8D%9@3%#&7(@.@B>D-;G+1?%C2!)=<1@D:>,D6+0..518%?5/';:@!76C,#:(A#.+%/GD'>G9.2*8;E/E%)'B*F81,B8!!"G*&.3H,<F2=4/"4B%=6F+A)7;H'A%(!32$".91#4>6/0?C/(<.C<(:$G0)?6A
@r2514
CCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCA
+
4'7;);21B%'759>7!6+.B;%:F"*-409D-#8&,%E#:2'FD/A@?.;%E8-;9/#H1G7;<9BC&;76<E'(/3.E@F3+D<"C64E/A&1,'GA(/C;$*DGAC!'1*.%A/>1A7A/)>G843@AF<9/!F,6.!44:8GH.)C<8A=CB//D.G->*0E<+*B+/+'>?(7'),-;=$!E0($)#F+%,&7&"7$!7:A;)G3>FD'EG3#!:-'805,60@-H<6.)(+GC,-0=&6##$$--4<(F+=27G0$.<-.#7E-/(C397!#E4"3E07B%2%E:>+:@A5=2HG<EH4E7=F,5?:,,E66@+
@r2515
CTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTT
+
HC3@->(;.8!,HD0=2"65<4:=9&5,H=<)E17A?43$%#17>00.
@r2516
GNTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCA
+
*$/A,#E?$-,&..5<@$9,2!6-722?G88:B!*@7"%?8&2
@r2517
NCGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATA
+
!H;.;4!9A83D>&A#:D68*6$A5@A3/71A(!=3%%A#,-A;F-3$D33@+H8:.73+$;=2F!4;,EAA(><E/3&(2(A61-C"&39&':3/C3F"(786
@r2518
CTTACGGCCAATGCNTCGTTTCGNATCACAGACCCCAAAGCCTTCTGCTTTGAATGCTGCCCT
+
<?*!53(AD*/)=;18F%*%H;(%2EB=>0B4(/&(/#,19#H*;B0$>#=C@9!$B1<2$HE
@r2519
GCTGTAGTTANGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATC
+
H#3C)$$<57,B17$%BDEFH!-17B<?@#>G<.%&-'1#27)#3@-!@"91:E1F=/'?/H6$7$,F,30#?8/)D<09#.B3::$C$=FB.*D:=DBDG+0;)H34
@r2520
GATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGA
+
;$.-(=G%E#31=:$A/!C+C*%8"=9$G2*@15(31>#HD3AB;(2
@r2521
NGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTACCTCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTNCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCC
+
'@@F$?=9<:,,6)3C8!0%GE3-??*933*A;B2<59#/11!8G?-"$/F)?H?E0F#>>$DC53@!)HC#8<*)';@C74>3!(ACG)D1<7A?+G$,;;E!87!E'$0E-B8$&4'(0;?>;5/431>8D6-7)$@*FF)$2"F33
@r2522
GGAGCAGAGTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTG
+
G:+?!(..9.2!<@'G%=A=-2HC,!%9:9$B,)1HED@5)-?C545(?C4%,A"B39;?=(7/17#B@;@,4/5'B2?E+6F;8&<(:&GG9<)B92-%<
@r2523
ATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCG
+
<1A(9A+C""F:80-5446E'D=?)-G(1@9D6C#8><*$+4-%>
@r2524
AAATAACGCTGCCATCCTCCGGTACCGCGCTGANAAGCCTGGTTGANGGAAGTGGCAATCCGGTCAGCGTGGAGGTTC
+
68E44;#A7FB!A5)0!##F!#%%E.86G2A2<<0*/6,+0&+B14!#)0D:21)$74);,0@8(7B&=!(8$01=>9
@r2525
CCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAG
+
BE1AH2H-5"33'B2<,-E2/%BGDF-EE,>!(!'&&:9A3"FA$2&"'83%4??'7?'CF0>D$;G.=7)@<'E'"C48B;,6?";G@96$EFH7A?1B(.H,7
@r2526
AATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGG
+
=@D/8354%DD3%(C5GH#!3#F!67H>%F9!?80A>'-.,%H57D)$9?;176HB,5938?*0%DEH.<!$05(@G?=AA&90?H6GHC7?69*B$C+<05E>5C7$,)>A66:#;!-9#2=&!=
@r2527
GGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCNATATATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGA
+
>"3:+FD0>0!A)?+#%!;;8''1?<2/%9<,D+)4=?.3@!99%/9E!7"&,:&*(D3>,!:!AC?,,H55H=7&/EF?0(E,C7F":@<E15G.$-(-%=(@"*:!&#.5":$02@,C@4F5%2-%3?=E.0H629<<&&9*;7&8C38C7C'$#*C50@+BF"8C,.(!-:5@09H2*-3@<HD>#CF9$-9?43?3('/2H2C?D)&B.!*%/H%A?5,80E2"!#.D8)(HB+(D8='184#6H<F;2*38G-A96?3@(*/&(:H6
@r2528
AGAGTNGCNNNNNNCTGNCCNTNCNCGTNTANNGANGNGTGNNNGACCANGACAATNATAACNACACACNNCCNGAGTN
+
!$!!#"""#$!"$##"$##"!####$"$"##$!#!$"$$!!$!#$$!$!"$#!""!"#"#"##"$#"##!!#!"!#""#
@r2529
CCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCACATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATC
+
52;&E56<1%;'#@<7HF/6F($">7747)=B(451F(5*@F@+9'(.?<E%>,#?3&5G#8$,?>72D::&D55@@GE%.3F++#>1#E:*#>,+38G>7/27!E$-@:31#&15C-$)%!,G*0;:.GC
@r2530
GGGGTGCAATGGCGATGACGCATCCTCACGATAACATCCG
+
15+.3E-6.;FH/D/>&($F&BB700!91?343A#!=C7G
@r2531
TNCNCTNNCGCTTNNCNCGNTGCNNGANAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTA
+
%'$##'(""**$'""'&"#"''#!#(+)!#()'&))*$"$(+%))#+(''&"$(&+&+"+$%
@r2532
AATCCGCAGGCCAGAAGCAAAGTTANCCGGGGNGATTTGCCCTTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTACTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCGGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGAGNAAANCCCGATGGCGGTGCCGCTG
+
(?='C8;-;<C2BE:.):3&7+#(.;):./?<$?)B!*E39@F2-B00E5"H-09.6,,#;3B%5?*A"=3/?*/9B/G#$+AB?93#<*6*$78!.8*2@1&<A.%$#:(?:846")DB#%&@(.FB,<97A3*96475/8>0!':2B+8#&&1AB@:"&#-5"=*2:H'=5520F@,6G'241")%CAE2;,5*4'B4F/1$27DG8#H941((72A@,#-@7%+?="%;$9HG#1'56*#/;>!7>>$9;23C,A.G6(A6")HA,)""2A
@r2533
TGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGNTGATGAAGANGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATCTGCCGGAGANACCAGCTTCACNCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATNAAGGCGNTACCNGTGCCTATAAAATCCGNTTCC
+
+#&&)&%%''&#$#'"%"*!"#*("*"(**+&)&&'%&)$)!"!*'#'*)+%'(!(*'('*#"%"$+&%&$++)'+#(%("+#$&"%$+%*"#*!%(+"#)'!*"%()&!('!(&&'"'#&#(&*+"%+""%('&!)**!&(#"&+"*$#*"%%)#&*+&*#')()%&&$$$!'$+$")$'#)$%))(%!#++$(#))&"!!'!+''+"&#()*"&"$("+"+"%$%%+%&!$"%$
@r2534
GCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGA
+
+%++(($"($&"#+&$%&+!('""%(#$*&!!*"'!(!!(
@r2535
TTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTC
+
,1*/>*C042!,3,')>D7!6>>.B4'7++/H>47H3'*=%D0<B?)43@*9<.=E294B/&9*3&-45D8/":;4<B>
@r2536
AAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTTCCGNGATGTNCCGGTATTTGCAAATAGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAG
+
?)>,GH1+D/*@C%1*E)0CE)/%D@!)F;828:A"53H%#?#5$),?B-.$C=3)1#(?*897-(4(%HH-3C8$H%=<$(:'&E%FG,.3:A?!5!:.=7*;;&4@E.A)258C=GE(B+"'H:GE@CHB3F+E+$&,H44H"38&+'9(69F7>=B'
@r2537
ATTGTTTTCTGGGTTGGTGNTTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAA
+
.!=?<5B7A*%D7+*15.-6G544*A/:%"$82C/$C6@?3B%E79*5DF8,DA*=(G0&1F8B<7**5H%00'%.F%
@r2538
AAAAATCTTCCGAGTTTGNTNGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAAACTATAATAGGTTTCAGATT
+
:.0F/88+=@>+*!<7#C+9G,<?060!?,D?%!>DC:7(8H!;7#%D%=*7;.78$H5B4$5855D9%1!$&@G34?=$)E$+5D%C
@r2539
GCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTG
+
4">$<&(/#E3;(2#@78?:=A+&<%*AC*?@$@+B847)0F*55F+C:9%6!D/'6),<2/C1,%E!D<$H%<"H<%GD8=41C1A)'<)?6?-56.8G66$&8/C-1)BH9:C9,#=;'8($4G,+65H67=@.)F;2"D3C96<25:A<#)
@r2540
ACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCA
+
&$9/!3!C&69%6E.?8.;1$G&?7&=,H>;E4EH@-1F/C&1D?+#@$->0-%'A<F00A(7;B0$%F)F.<F&.&9.EA9-A>AF
@r2541
GAATCTCTTTGCATTTANCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTCTTGG
+
''*"-"5=C6+1<025?E5$)G;'9,G*%?3.41&G9)=//!9>6>.F392A'$@A@.:E5)#%>@99$A
@r2542
GGTACGGCGCTGTACTAGATAGCCGCCAGTATCAATAGCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATC
+
C%;*A%.AH(AD8@>5";D97++(HE6@7A,2%/1C)>A%/#15)##-@E(!&22?:0;'9?<&F.F$)90%$CA&E04@A*?D1HD!5#*AB<5
@r2543
TGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAANCACTCCCGGGTATATGAAAGAGACGACCACTGCCAG
+
G+=%8B1A!'<3F2>>7C6&;?@55%C)HC3(=&;@$H>E%8823!H1EG2,?':2,E*B8F?:>5%;#?CG'4=-06HE*1!:,.72!&3+D;9)44AGE#/#,H4BF:+:6)'"(F@<1)%4;8,5C/+:D/=(3E=-*0D.)0AB>F:>(,C?
@r2544
TTGGTAAAACNTTCCATGTGATACGNGGGCGCGTATTTTGCATTATCGTT
+
.'@$$ED<3#>4+5$#?8HC=+/8-$-3/%;68.7A%7)8B!0*01;E$+
@r2545
CCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGNCTGTTNACCGCCA
+
D/$+0;=BG=%@73)G4FA4C65EFB!+B-;2=H=/CC7+G,#!>7D:&(9,53--<3!<0#F?=+F++6#0/6G;.7?)6<:3
@r2546
TCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTNAATTCACTATCGCCACTT
+
%D6E>==:++,2&*$(8):$%FF5;/2%3'$A=?8*:64*@:-90"*=+'@??*E41C
@r2547
AGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTCGACAGATTTGTGTAGTATTCTGAATGCTCTCAGTAA
+
GBE*7.0+65(17#:C6H>'&G@?%'-'/55E"7E&B$#<;8<%2)23>+8%-61H=9,2"7B0$=.-G(83AH:"48!836,%C(G<D96C;*@/-C.C5(C#)(%-;3G"=H'(E*
@r2548
CAAAGTTAACCGGGGGGATTTGCNCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTNGTGGTGGGTAACCGTCGTATTCCC
+
8$#%!#&..F6)-?D$0F=E2=G<0@'*=+%(4F-.2!64)5.1=E)-*3,>!"-E0)?$(+0#A4%++2G90?7B;<7%:.-.-)+"=&,"6+6#9+)<!$!.>;G1-24&#<+23FF"'=188D5@#@98!F?1@,&D"2B73"
@r2549
GCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGNACAGCAGCACATCGCCCGGCTGTGCCGCTGACA
+
(H+D29*'H,?2?F048,'0<=.<2CED#E290D/"&3.D2@D#%>-'?%2%GBA2B6HC>A$F8#-9="#6881!E6%G575GF5,)4:65,-!4!94/'%&%-41<;H89CE34DF%117GG//G<AG,6HF52'0?3%C)C'D/
@r2550
TNCGCTGGNNGNGTGACACCATTCACCGTGCCACTCTGTTCGCCCTCAAAGTGC
+
!#(&*%')!&*)#+(!'#$)(#'*!$+%'"+&"#)'&#&!&#!*"'$%$'"%(%
@r2551
TATAATGGTCANATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAA
+
=4G&@&=BF1BC@/%&H4#"E,AE7<%"!%H+3B#5;6.255;2!;5)'86:E;)C"@7'G19@%'"!/-H
@r2552
NATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGNCATCAGAACCGGCGCGTTTCTGGTGGCGATGGCCCTGTGGCATAANCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCG
+
%A$4"?ED"H+2F9@9B&/:E(D%F,=(315=700D$?.34;AHF.D)6..<#0,=1"2#?,71F=*%H.3-8$6%C6-H'+%!-G08(!-E7G-3,38!%6:590B:F-=F?B$#G7%3D5F,6#!;1!*"'&<@E1133;'8,D&<@@D-3$B0*.=#B:/(D0';%8CF';C&<8!<:(A!;0($D6G5==))-+F&(C%D/=-:0>C#;:A4';,"90+@1D.%7(:49>?><A6#1?>66;1E,";%("78E">B("22#',4:!>2CC(G5+AA14H=%B;!B!A/*DBF.62:<>DC%2FE
@r2553
AANTGAAATATGACACGCCGATCAGCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGNCA
+
*"(**)%%*++&"#!#))$'"!**!#'%((##!(%+'%+!((*%'("&')#&'&)"&$"$)'**!$%%$"!%!!*!"!%&$"&"$(!%!"$#+*"$'#%#$$(+$&)$)!+%*$'*#'$&#!)&)"
@r2554
CAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACNGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTNCTGA
+
<64(%*C<*-1@7CGBA*#8"4A&43C.+#<9:"&,F=AA6.(D#$>:259*17%:G"5&;B?73;+/H%?.9.056$.<AE-E!!:>#1
@r2555
GAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGNCAGACTCTGAATACCGACT
+
/DF:#3'*16;'<F=(;">@+;C>?-0G8?(-0*9$7<8$@8CE5*D'0G@$=D)C9%A/!1A0$19D1.5$.GB507'F8@/
@r2556
TNAGNNCNGCGAANATNTNNTTNNTGGCNATGANNNNANNGTANCNNCAGNAGANT
+
"!!"!###$"#$#!$$"!$!$$!#!"$$$$##$!!"$$"!##""!"""$#!"!#!"
@r2557
CTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTG
+
<D!!=C5675F*BC8&D:,:%.A3>$06>B@D!>@,),'#)%,AH@=7-(>C-76A7
@r2558
GCACCGCNGGCTGCAGGTAACCTGGCATCTGATGCCGTTAACGAGTTGCTGAAC
+
*@&E+6>##>H4;?H#(D/*E3!:#'::'7(8?49-7B%%*H,.(%&=838EA+
@r2559
NAACNNCACTGGTGGCCTCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGANGATGCAGCCTGTCCGGCGGAC
+
!%&'&!+"*&"!)(+)*)!$)%!$)+#*)&'"$%((#("#)%)"%+#"())!"+#%'"$#%+)!!##'*&")'%(#&%)#$(#&""&'(()*'$!'#'"(*#%#")*+#+!'!!'&*(#+%**)($%'%!$'++'()
@r2560
GCNGGCACCACGTCAGAAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGANTGA
+
>,/33#);8G284HC/H2<(,15,+=C2:F9*5B"8!(9<F31(/0(-;(986$99?96"
@r2561
AATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAA
+
1-##&!#,6+=**+.)<?9D@*FF.:3@6>E0C7%B?C9*6E0<?..63214C,)D&;,<?50)20C-@5B065:D0A.2%GH4G</1@F6C@5A10F03@*"0<<1+6,
@r2562
ATGAATGCCGCCGCGAACCATTCNAAACTCGCGAAGGCAGAGATATCACGGGGCCGTGGCAGTCGCATCCCAAACAGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGATGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAAC
+
8)6E=/%'0"BC7"*";6)4/:5G2)CF.21)5'E=%.0$%/!?*1*E7626$7=7&GF&57/5;#0=8#G<:$G((#CB*5+.7;$!)@)AF:<-';6B:+?3F:$:G;&!.F27!,=$=+%93*.-$?$<!@.,G=&@!("G;!,4,@$0856=1F'.>(G$>><'02<77<#);+'?A@.96+=6#>BF73&'>>CE%';G
@r2563
GACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTG
+
E0);7@%C'62GB.*9'A!C/C<607":A$5:1E?.'6'$2?"":#B''3,91)*$
@r2564
AGTTAACCGCCCTATTCTCTCGCTGAATCGCAGACCGAAATCACGAGTAG
+
)6!?A85::>H?4.'C)89+=18.H96>(FEGD"?&<."(#**/#;)(CF
@r2565
TATCGTCGGGTNTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCG
+
@%&D5:.*&AH2"H;4"EH1<?4,!#D$%E*&"$</1((<3#HG9<%5)>&1B>"=GE7H82,39D->6#+<>.(25'D+>-+@@4B<>
@r2566
NTGCNAGGANGNTCTGGAACTTATCAGTNAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGAGTGAAGCGGNAGAGCAGGCAATGCAGGACGACTGGGGATTTGACGCA
+
#)&)!%%)*!%#)+&($#%#')+%%(&&#&#$!)(+'%"#+"+'"!&%'%&!#&("&(*($"%'&)+!&"*++!*#*'(#+"''"((*"#+"!($(*&!)%"!)$*#*&)")!)'*)(*&
@r2567
GGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTT
+
C5A-3,CF7'@16*;,$6;9/4E,1%FA3GG2!6@D+7B>1#E6*1H='07!A1%@C?)G#G&<.3<>4C803>/=D9*6:.884@F!;#4:>9G45:"=?4>+8#$HF?;?$3/13-)9=H+&9<5DG=1?'7""5>5>"<<DF,;5#!:5>$0"H)$7+;A>C.'()<3$'A9-@::?@4<&/+#=>
@r2568
CAGCGGCTTAACAGTGCGTGACCAGGTGCGTTGGGTAAGGTTTGGGANTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTNTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCA
+
=6-?<C%37:C&;9-D*-70/#+9(?8GF:*,!&B0,+EE!6%A?3<8%6&9(D6"@D?-#8D-,0H@<:6@F9B-+8%/F:"A&6":0)$7F9*E&97.B'6G;D&F;"$*+-1==*H#D>6-1@-.B>7!=9(FD'AA+.2D+2/)>)+4,:7&A&EF,.'(G9,!15:G9*//?)@&@.*5
@r2569
TGTGGCGCTGGTCCACAGCCACCNCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCC
+
D%'<;5F01>>#?$,%3=79'(=B516#6'<=;>%B7G-=%E(F"*@/H'B74G"<;F$C(1A9()'C=B6E,0"!4/'0?A?.
@r2570
TANANCAGCTCCACNATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTT
+
#(!)$#&&"%(%%)"'&)+)'#'*'$'!**!%)"!#!%((!!'&(&+##
@r2571
CGCGGGTCATAGTTGGNAAAGTACCAGGCATTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGAC
+
<&B!G$=2:B&C0;E5$(?$*<#2;=D2,E<&501E!;8C10:)@>?1F>B3&G*6@E;%-FD',5;127<GA2*6!=)9>B/F
@r2572
TGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCNCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTT
+
,,7@;)"*)<H/.)4'5-B:?2)";3'BAB%1.C'>4+)(&8,"897:E$<!CB@=C<F1()<9&)A.%':,>'+A3?+=8E/D;1/>';?;>C2>;#7(9@(*<"=B@=8>486$=97B',+4H=
@r2573
ATCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTACGCCAGAATCGCTG
+
-?E6G/("),8$5H%*CF%9G)..@@(@+A2<$?(E!86+?:?=+D4H71;.<;74E71)B2HD=@G6H90;@B5$=*<(-@@";;--/D4(H'5(A99'F1F@E)52-:
@r2574
TNTANAGAAGTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCTTCGTTTTAGGGGATTTTCCCTCG
+
!)%((&$($!+&!'+#!'%##&!$"'#&)'#)*'#(!$)$''!)*"$'&+&(%*+")(*&(#)+"(%$!'$$""*&"#)!'!+%*#'#!#&*(#$')##&!!%%'$(!*!'!)$#*')"%#*($('"*!*(*(!%
@r2575
AATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGNAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTC
+
2;9!4@0,$(0F3C5.*)D*(%,7C9'"(%%<)$AB*&+68>,6:$#<";$+7E93!G)##='/"6%7/(<#@>+-2#C%D!76%7)'E":8'D0*D!<&1
@r2576
NNCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACG
+
"%''+&'"&)&)'$%%$&*&(%##%'((+!*"+$(%&))""##'&%"$("+#%'$#
@r2577
CTCCAGAGGTTCATTACTGAACACTCGTCAGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGGTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGTAAG
+
#>G6-,'H-2E9/+H8(-:7=,)#D8*$+:>4,%'GE'%E-9,24;/!B5#7!848E?CGA1')#C*@0A,':H%B&,B5/5>6:$57.:A:/9B?C-+'B&B.5&"1%.@5%:'H$H$H$>.1B599.<)34.#??!&.&-%-EA,H?9@42#'>1)%&!67@BG-,%6B,,F>A,%/?8<?>%=DG#&FB421@=B*593$?2#"A&?9!0?/;=F-8.4&H54#1.)-&;G=7'C'4F%7(*+"EG:5B$/AF>G"#<6F2*A?;2%2+8(.4/2#=3(%$E)#D);C38?2$9**$!@7"0H6"%@@.#1!0;>!)=5$
@r2578
GTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATA
+
/<'51=,'9%$:#GF"(G:*0-3H?'.-$:E'/9-&/4C7G1@+"C>&7?C"A3+2=83"+$:!
@r2579
CNTNTTGGCTCNNGGGCNANGTTNNCNTNTTCANTCATNTGGTTANGAAGGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACNATATCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACATTNTGATATNTAGATGATAATCAT
+
(&&""&!)#%%"'&(!&"&!($(!%%#(!##'("*($*#$)**#)#+%'%(!)"(*')(*!%&+)*$)'*#+%&+#'#+&#&&+('+%(*)"!'&'*!"+&!#)$"&$#((&(&$#*!*))!&)'#$%!#+#&&#%(!"$'$*++&*#)((+')(+++')&*)"##$*''+$&*&&#)()+"%)"$*$!+++(+!&)"%"&(((''*($"&###*$"')$))()+%%*%(%+!#&((&*"$!&'(!')'&!()(!"
@r2580
GCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACNAAAAAAGAACAGCA
+
-.B?93)CG7>;DB&(=5E/444*+04=<2%+F'&)<G$"G)HDG+=3@H">!!-(&/(%$B5
@r2581
GGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAG
+
?@9G'E.->G@H2!#C('AD6G<C>$/%1:<F)A65HFH3'(;";:>E@
@r2582
TCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTT
+
=)+8?3;GC/.&>?,+A>"1>'+9#'H)+"3&+0B>@),=29HE)18=-'6>:F3
@r2583
TTTTGCACTTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGC
+
82HA-:F-("#$B/H(12()0+@AE22E,C;42>0F/2C?="F7B075H&99&4>3F).6G5$*%!4;:"$#7%451;-?.6CC6E78'8#/05*.3@33/%(0!H'5:=+)5+FBA>E@$3D
@r2584
CTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGA
+
@@(7-E2A*3A>.:9+<,89+@=@18!F6,(7E!EC(+)D8!$DH$E>%("#3(AD>B'1;$A@7+A*3%B$()6@.$E8,6F=-+G=B-A!8=B(98-D&
@r2585
NTGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTA
+
)%+((*('!!$&&'&%!))+!(*#('%!&)%)+%")&"'&#"*%!(&!$"))"*!)'%'"++##%)(&
@r2586
CNNNNANTTTNGGCTCCGACGTCTCTCCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTCGACAATCTGCATCCAGGTGGTGA
+
%!!"!'$**$$+"''"$#'$')"$)(%(%#("*$#*(&)%$%'%(*"(&#('"*(+&*)&+''$"&((%#($*'#'&*+#%!)(!!&"*('!*!!#!%*$&)%!&!$%$()*""
@r2587
TCNNAGNGNCTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTA
+
('#"#'"$$++!'("((*'#&&$$"($(*'#$)$'&##!&&'+'%*%(*+"$
@r2588
GCAAAGAAGATTTCCAATAANCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCAGTTATTTATG
+
C<!")GE)+/<06;&-*/CBDA&G4)/(;;&H6@C=+.+0,G*1$%,,4#15A)$67?B@7"DCE7=$7)5$*7E+AE$C>F#B2.@00,#B4B.&37B446$/9:(;2:FGF7"GC5!
@r2589
GGCAGATTACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAAT
+
=$4!<=-E2$9D97://AB)@>/$=%>A?C')9=;46D$10;=+=A#B,F:D,8&'(:=D,+HF$G!H#;??7:0BG<?0A0,)9!%!%,5<E>##+3:,/:
@r2590
ATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGNTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGA
+
/=+CG80$)3@:;/4.BF:FE&"@)F%7D7H$-D7%=;,C!.AF:B2#+;74=="A0$$.$6;/$+D5G$93##+%4F+#/.+$4"C<B;6=1:G+5G!0)EE7.:.4F=.E33$8=D'AAC6%0:.4@/D+8>2.$*?.#?D9'C58(E+,&41:6*"
@r2591
AAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGNCAGTGCCGCCTCCCG
+
GF#:11A873H9CB2+(C<H$(6!>2EC/?.@-0)0338128%9)0!;78H/:>/:-%=<-!'"'.,4*.$'
@r2592
CATTTGCCGTAGCGTACTGAAGAAGCACCGNGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGACGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATT
+
E/&!?(/171/#E;0+#44>:#F!.E#4E-%(%3)27'H@>,05#4?D)D8?H+1-=)C1-;0BH$'(,<*/$>/*1*>,42"D97(2)E-B/A'#*?=4%'><:,E?-C:7($()?)A'!6552?#/36=-3><:#8A*$93;%$ABA(-+A-.+6$<'(
@r2593
GCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTCCGCAGGTCTTTGAGTNTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCAACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTG
+
2BA9.1*)H)0H($CC'=/#-7-7G%(G,?=70(#:6@/B#C,!4$%CC2A!A"8)74&@@'>HF"<EE$1441-2:;"8&>600.A<3?+;&7#6<'*)-"7#?7A""266D?.,F%==>E(5+2!.2B(#G"+48;3,$>HA-G1*73@?)DD0-!D+)F-#$0.7D"58?)3?'HB-,&"C.G>5)5#3AHD?=8$#&#!(:83C+A-*$#!$,=",F0AA3.;&-$=8#9:;HA/:<.@B.'(H#/,*<5+4<09,791<6?6&F*7#)!!;&:55@6H=H9&&,C)F)
@r2594
AAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTG
+
+%))$*%)&(%#'($$#"+%)!()"#"))#!$$%%#"%)++++""!%)"))&&"*(("+#%#%!&'!&+
@r2595
AGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCNTGATGATTCGGGAANGTNTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGC
+
1,E$HEB+.>6GC<%!-G1%+&+$!+=$.3:4BC(0:@&CE$8>-#..H5D,$?/>9!5DB(@C!+$3G&-"#!1<6B4CD%F"#0#2+H+(G61&FB<H#/0"#=.CF#2+'E:"AF'%/.%50;8915?).7;!ED>1.'0
@r2596
CATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGT
+
7C1&.8GF@&%+6H,$9,G,'#98FF?&3,G!&D&"<+5"#*?1(".H,A!
@r2597
AAAAAGAAGAAGTAAGCACTTANTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGACAGCATTGACTACTATGTTAATCTCAGTCCATGTCGGTGACAAAT
+
+)+#*)#&%&$!+"%+!$!'#"#)**(&#"#!'+*+%+")#+''##'*%"*'$'+(+$!#$%##(&)('!'&%"##(*)(&&!!%#"%*($$"*)'+!"&&#%+%(#(*%%#(((+#"#$&)(%
@r2598
ATTAAATCAGAAAGACGNTGGGTCGCTAATACGCTAAAAGATTACGAATTAATACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGN
+
7-/%+?22;<FH=@?BFDD;/F.D07=73C9E?7%9G@0?&0,#8B@E%/2@94,'B-G5F%BBB60$HH?D?*7=D2G?4!&*H&-:12070.,-#)AB7;C)0#634!929%H-F&4#':H,'F;B(45!(E
@r2599
AACCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGAGCTGATTAGGAAAACAGG
+
)"+!*'(%+$")&!'%%#+%%%$*((+''"#%&%$'#!&#"#(!(+*(!*"'!'+*&'&#()%$($)%*(*+$$)"&*(!**'(+"#"$&)()!)#$*$$!%
@r2600
GTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCATACAAT
+
,9&,1CG/!8384.#42<%2H;)*CG#(C:,(%6BG*617@>$'-.H!96A3"FB$B7.#F0:4HB*%:3,+@!;7,G4F
@r2601
CGCGCCGGTTCAGCAGANTGAAATCCAGCGGATGCATATCC
+
+%("&'*($%&!''*%#'"&*&")*'&#%*#*!$")"!)'*
@r2602
ACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCNGTTTTAACAATATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCNAGAAACGAAGAAATGATGGGTGATGG
+
5A)?2B;6?5##*4-&!!FD)5.'$E:8CEG"H#*3>A2#)%/03)'=7&$D'%+1>GE&93@FA'!+->1BB=>ADB;42!E,'F=/3$5<(H:BED$EGF*<FE*3;:;A86EHH=D6&0G,"2='C@:8)AC394/-,'EG:1-8/#$D:<1*-49.&?7E)*C3#/0AD/97(*&519?)24'-!0%<38E999;4=(,/3D)D'C%+H6B/3=EE/3CA.1&-BHG9@94D=*5>>!58FC91<-'B
@r2603
AAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAA
+
-<!%$BF#9A@4DH/521)!(909+?EH63G(;'EA2(HA+8;2*CA3?.%*(9&%GG/"2;0'#9D67C35H)3BHF&+G.$$@@.9(CB"7B:>16!:5@+
@r2604
GATTTCCGTCGGGCAGTATANAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCANGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATNATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACNCTGCCGATGGTAGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAA
+
!)2-H9;2,'"7C@=#CBCD$DA<#0)8-0?9,+!84&-%2$2,"@"5:G,%/,)$?+BBH!0!!?A(-$)328*D&69>+C?:1<-'?320F;B13H"H">@?1("@>=?;A+A+7<FACH5*G*274(%'D&BG1'B5)7=).,(/),&+@/>F@&HE,-7-/,.?#>'20A)$;6F?E39D!DD4BFB4*G-H>"7?8%G5">C.0<$17#A6*%=0772E7$B!G(*3<C11@E.0*F.GB2)3>GB7&+4="$9#"H%"<1+8#).64*3#G
@r2605
CGCCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACNGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCANCTCAATTACTGCAATGCCCTCGTAATTAAG
+
(#+*'*("**+!!&*'$+)'"#%%(++#%&*)$&&+'%('''"!!%$%%%+'#'%*)()#)+(#")*)("%!'*+(#'+)$)&+))()**!%$#+$!)+')#+!$"+$$%#$$&%$%&
@r2606
ATGACATATCGGTTTGTCAGGGAAGTTGNGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTNGGACAGCCAAATGGTTATACGGTATGGG
+
+E2D:2@>F%5,'*.C&+!.F1>)=0:&$(-0+2E+,14<+/FF@%%'A:-0;.79-B)DE"7,B+F%#$*8:6+0@5$6B+E;G">9"46-F)02:)'/B'H':3;6,6(7
@r2607
CCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGG
+
+D1=/(F#2FC/'15F$3:+,!-*-&*5?'GC7F:@+-!.A@+&#@&>!)06!:1::1$/25
@r2608
TCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCG
+
:;=(G+8!.#+('&(G*EHB%G"=.)(=*49D.<'):%4@"F@AC6=9/(C'D54*"
@r2609
TGNTTTATCAAAGGTATAGTAATANCTTTTATGTTCATGGAT
+
)'#$31!A4.8$.HEA4A@)G"A,..(!-*=#/%H1!%@"*@
@r2610
TTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGT
+
B?7:!$>8'19%2#8AF<D&)!5'!2/A$%HC%$!@9E9F(7>DE)4>%'!2?"H67
@r2611
AAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGNTAAAGCAGGAGTTTTCCGATGGGTTACAAATAACCATGAACATAAAAAATATTACTATACCTTTGATAAT
+
%A-688F71H@C(+7.;HDH655:E42)B4?('.H,28-,&7<%F;+D4B-$,,BA84:?&F'H6?>09@>H!H.19CG/->72'H'-F%3A(B$(!HB-1)F2$:.E!94-A!
@r2612
CNNATTTGATAGTCTGGCGTAACCATCNTCGAGATCTGCCACATTACGNTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTNGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGAGAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCNTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCNGTCC
+
&"$("*"+##'%$%++*"')%%")&$+'#&+$'&$'!+++%*&')"+!'"+)**+*)*)*(*"!##)+'($(&'%!*(#+"$(((&%''*&#"&%#!!%+*'*#)'"(!&!''!#'*+*##*&$#')!&&#*!)!'&&!+(&!&)#+&*#$)($&"&(!!"!)!)#*$(*))'%*&'"(++%#((&*"%#'&"(*&%()#$'%(#"%))&!&'+%#*(!'%'$*$$(+%'*%($*%%+)(&'("&(!$&$")$"&!#*&#'#!)*!$+")#(%&')+'*'+!+$'%%$)"#($(%'&
@r2613
GCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGC
+
-(")!&:5=;2"$FG"89&4(?+&7$/1=42((@--"5:?A1#H#G5?712B*1A;<87?<!@F"6??,
@r2614
ATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGC
+
63A!.H7;;H5'&9!%.&B=CA>8=FA2"1>,#;A"728)))/23&B@<4*G$E6E=FA!'63.81/,
@r2615
CCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAA
+
B+.?H3/&&=!2>;27/,7H3C:2!H<9&%<AG8G*F-1D4EC;=D:4BFH#AB%B:="<'4HA8*8>?+=6F1(("
@r2616
ACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGG
+
GA1*"7D#2")?"/!H$=;!"+E)"6$3,'B,89<-9.6+=,8?1<+=/(E1&+@5C=
@r2617
ATGNTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGAGG
+
FA<)-!4%%$72F#:?0F$6/F7401DC<D&8$115,="%(')1<50(53!G&A
@r2618
ANGNTNTCGCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGNGGCTTCAAGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCAT
+
("""("*&+(&#(&&'+#!(#!"*!$*%)%!"$%$#($%()!(((*"#"&+')#*&%"##&*$#&%$+'++"*""%*!'*))*)'((+#&!$%)&%%&(%$++++%&(!"+(!*)&%'*)&""&%*"+()%(+)()(#%*#!#('!&)%%"%''+$+$'!))&)''*#'%""")')*$"!&##(!$*#(&(#"+"+(%&"(&$"#'("(!"**%'("!'&&('""$""%(!&&+#!#+!&%!&*+(!$'%"'*'$")+%&!%#!&$+$*$"!#'#++)!#)%#
@r2619
GAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGAT
+
3H97G;AF/6@D;"(A&?6#H6/%?#:AB;=06;F'@46A#AEF1'6;4G';@H8:5<.';&+3/+1/;45>0'((/%83-@)3:'";!81DC<A=-;2E229-1/A"EGF#'#:%=$A8AF,0*GEB5"D?#B7!
@r2620
GGANTCATCACGCNNCNAGTTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCN
+
#'(!&(%*&#")(###!%")#+&*!$%)''*#+$$")%*"+!'#'%'&'$*%&'&!$((('
@r2621
CCACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTTCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGNCATCTGCGTCTTCTGCGGATGGTTATGCCACA
+
%B#)4AH30(7<$CH(-EC$084>7E9.'(,&1.,!')8%;,@!9*+&B6<3C@&=>)F#;79")#6./'63(-96($:G5*B+@36<@B>$+8>78HHA<1.*H,(9B1B*8;.7C"$A%E6
@r2622
NNNNGGCNNNTGGNNCGGACNGNNANTGGANAGNGACAGNNAANNGNCANGGAGCACGNTNANCCANNNGTGANNATANNNNTNGTNNACNANANAGANNNTCCNTGNNGNTCAGNNGNNNAANANCNNNGTNNNCCCNANANNNCNCNTNNNCNGANNNNCTTTNGNTNANNACCNAGNANCNNNTNTNTGGNNCTCNAAAATNNTGNATNANNNNAACNNNTNNNGNNNGNNCAGNANGNTGTAAATNCGCTNT
+
"######!#$#!#"$#"$##!#!#!!#"#$!$!"!"!$"$"$!#!"!$"""$"#$!#"#$$""$!#!$#!$#!!"##$#!"!"$$!!"$$$"!"!"##!"!$##"$#!$"$$#!""!$"!"$#"#"#!#!!!!""$##!$!!!"#!##!!""$"!#!$$!""""""!"!!#"$"!#!!$#$"#"""#!"!"$#$#"$!!#$#"#$!!"!""!#$$##"$!!!$"!#"#""#$"##$!#""$"!#!$!#"""#!$#"
@r2623
NTGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATNTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAANGCAATTTAT
+
!E5.8H65)(2*!"D!0E+31B-7409-C6D,908+'(>70(E6$605E$GC(64)&/C#4)!A'F&B58E@'@'F23054G*$A$:6-(4>=499-F.B#'*77!.71#C6<*7<"&.@:%4D#9$40@+233(5",,!"#E-!".%7?DCB74<=*>,4*5*&70D8$HF/!E2)8F79&.7#
@r2624
CCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCNGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTC
+
$*?;-%>&#!C#"8A1C"=E2(-6B&./+!4;*83C<E'-#B2=D';AB<3C"=5D0$/7G/66#G,4D.G&+#EDGCAF>C!;3E)8H7G+"@D<*67+)=8HF*4C#$3',1B&5#6!#4@:-191#G"GG/6,=3A$,3$C1;2)
@r2625
TAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCC
+
G165:497*2-FG;/0!%(F0;5>@3-.D0*/0*?32.)DD02C7&H(7$,1#=)1D2?D;5;47+<B;(?9D6A'!?,H")D$(<+<8+'*=(3(-<8%'#*/%9=E1>B$B*?!+D9
@r2626
CGGCNAACCCCAGGGAAGCCATCACCCCCANACTGTCCGTCAGCTCATAANGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCC
+
%89BE;-'/;B@C88-)C=;%)4);+G%34@F4;96?@F334)(G>CC>>,-7BA-!,BAC"D@9*9*?(9A%</(#C(5<(D+&<&9-48@G+"3$+/''
@r2627
CNGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCGACNCGCTGAACGCCAGC
+
%*+#*$$($)(#''((&%&+"#+)+))%('!+'*(*!+%"$##"%$%!#'&&*""%&&!
@r2628
AGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGC
+
5":*D$E'3,"1+175">'9+"B.#G6)'E.C5-?2%(!?."+D'!/!;F&
@r2629
GCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGG
+
-')+(.#2)&!E911,+,?/0,)7B13FA0A-&B(3D=3?'#*26A<6<:/G9@4C+F>G2A
@r2630
TGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACNGCTTAACTGTCAATGTAA
+
;+5$8<,!?0$;CAF6(G))#;)82.BH0:/;-A&<A.%5+<#',2$-'4*$%H25$))/B4$%E>:+2*D.:%+&91G>5'0=-%6%/9>19'%7C+4*$73191=+;C"-+C&!<./?5(?!',5?(GGD*1?,$->)%8&3#;$)1&42'
@r2631
TGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCA
+
/C%;4@E$=':%G-@BB$BD?03D*6)A+6CH#,*4;"5-.-0">-B+H=%"39H+C8"&7,BA<H$0.F8!5>&A!H,8*#1%74+$!,,D>927G;A1G.3+"5CH9C?A@<@CH;+A'3,8'8D!;=<::5&&=/C@<$5D1?.'>E8=HA"H7**
@r2632
AGCCCGTTCNCCACCTGNGTGCAGATTGTCAAAGACTGGATGAAAACTAAAG
+
?H>B#C2&D(F'.G/7$:+*,-;@F9*?1::*'82G5!.D#5<,*-!-+2,H
@r2633
GACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTG
+
;D7DGG9$,'220.@'$!?!86B4,D=/D4"&EC%CF/(!6'#9#$59895=
@r2634
NTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCACACTGTGAGCATGAGNCCCCGTGTTATTCGTCGATTTGGTGCCNTA
+
!2C<8B<;GC=13'EEHH!A@?#'3*6->D/D1!+5%G7"9,C9></?F)?C'-(.%2$17>2C5.D*#8!$5F.*!3@/5"'B?<:CG'",!$#+0@D=79FB)?331B567G'G8?72*0:4#G"2$,&$-*7?9G4-;2'-/FG;:48!1#+/,=@FG"GE31668+1G(.1=E60:@8)*<:;='#"4>6'E7(@!6):./=@A9;!H"0#61@F>2H69/C3C
@r2635
GGCAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCAATGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGT
+
)6><!3-%5F#8,F1/:<(6A;:/8D#94?2'=6);GH3;?E/%%>9@.DB50@5:8-B:'.DG05/87?-4+%*)7F6A7.&2959:10D>;&H$=2H&:??*C9>:B>,36&H>75.;1D+$2B&#)@#5<,D-4-H:D-#A<@=F.A<;1?1C9@!/
@r2636
TCATCNGNTCTGCGTTACCGAATGGATCGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGG
+
*"))#$#!&%+"")"*!*+%%+!'$&$$!%(++%$'$+)""!("$%%*%&!"+"!**(&"$+)"(*')+%''#%$*'%')
@r2637
CACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTT
+
+-A!@C#8.'.:8E.++9E"A@%*BH0B)$G80>@0@)*>#3#$+H"B(35$B"@A(EHA>)DE>2,D@C+:6#17%B:;.@E.3$3$:.+0*$3,'>=G#D63+HB)3!!GGD=?):A
@r2638
TTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTGTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGC
+
'C7G4+0!&%(;:#3G/H54!+)$E?'*%B870?)/-"5F(D25;:(3A'2#9?1>;3&G>@:;'A)(+).4'H%$?)$F$$(:*8C0DE838:H9A@8%D1(%3=>9118H1&:5.$7)&$2%!HF&G(D.;5A(G?&0!;D,=59.*0%
@r2639
GCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACNGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCTCTGGAGAAACAGGGTGTGGAAATC
+
/?=$5A8-D("A1<:;CC.$+A(,?>66%.31<=,14$>82?=F.95//74$HC8H"#-G>C1=--D$0#&F*=161C(H#4?96$55(5;H&53'#=F%E!80-!7!*9"2,"/'4&*HB0$H%<!>7
@r2640
AAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTC
+
34)DD$%7&6=6942:-&A0=E"!D@DF$C>B#;=22CD17BHB-CD(H*+HA@FD*C5!A0@906%A?2#14?E279!)6D16FF?''<G"$51#C4.G7E#2/.7>H.AD',!)FAE=;3H5-)1@+*
@r2641
CGAGCGCCTGCCGGGCTGANTGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTNGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTG
+
9H>E0GF+")0<A1<G&FAD*7*6?F&--&8&@5<<D!81;13543@<5@>;4,'-;BC$F$+;6(F3:6#68@(1*H7'19):?G+*)'5H6!%=4/8#$@.H3A,02F&%>3!!4&"<C4F:<E;!/=1)BA*E39)&C>EA<C&%C#1?.$CH8>F
@r2642
AGTTCAATATTTGNAAAGTNTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATGCAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTA
+
?&B4/DA9E/,0%;0@!3<')*EC6C/CC'@4;B@"1,C?"H,%4D*8**5:71&1*H72)6"!@.'4#9+"9?'CH'"'/$>?53!.:C/C=>'/6,*C1;'@),B,AG);7<<<4(1<2%G$5;GC082D*$9F@(5%8<7H<D+&D+/+)?;+0E78@01A/6C7<D?D!E8GA9F4&(/B309H%1$.?H-+1=C0;$0:*+FD#+<)-(5;7D;@;#55G:*?8C$>%0!7D
@r2643
CNCGGCTAAAATGGCACGGGCAGGTCTTCTGCTTATCGAAGGTAAGGTCTGGCGA
+
#%%<4.(2;<5C@G,;A&0D'G-46=&),"<EG,F+/8"G>H)'4<"*,0.)G*G
@r2644
CGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTTGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGANTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCG
+
&6076+7E4=!-064$,)HF:C@3,)3CH*H9/3$:)563!<C1,.+)38/1")"8H!0;G9+5'0BAG."?/&$;/<C7G9*;762.?>==:7/*"36=?="7*3=%>E0E%7-)G4=,H'GC'CB"4*2'137(2/'=11==7D=#$7CB3,B55&6CFBB0&4G>F>D?.*@$/*,+;,/+"
@r2645
NATCGTGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTTAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGANGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCCGTGATATTCCGT
+
("$#+!'*"%'&%+!%'$()!%%$"(+"&#$'"'$!%&#!&#%&&'(!$+#%))%%"**#"""()#&#%!#&*+$#$&*+%('%'"('$%#'"$"%%%++!($'&!$#%'+'!+)'!""&(')*&$!&"!$!)%*)%)'(#+!#$%+("%*%!"+$*$#)+*"!+)$!(+)#"++#(("&*('%(+&*%#'((*%*#('&"!!'($
@r2646
TNCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCANCTCTGAATTTACGCCGGGATATGTCAAGACGAAGCATGNAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGATGACATCCGCAGAAT
+
&':,'7/%&&+3)E.&B70(3$1,&0:"(+-$6@A<0&(4H+E+585"??F8,@A1@9&%8E9)7EC6/6(8C'.(?%5,94:(/168.G='/'A!B--A?$#B)H1,@<-#&4+"D5+-+,":8C4@"
@r2647
NTNGCTTTACGGCTGACGAATACCTGAAAATTTATNNAGCNGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAA
+
%%$&)"')+#''%+)%)+!$!+"*)((%))++#'"$'!$!+&*&&*$!$'&#(+)$)*"'#)(+'*)%%$!++('"%&('
@r2648
TAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCA
+
C+"5//.02F0'#5*:."86>(15&1?'%?=4D/$0./=D*;+B*2+&
@r2649
NAGATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTNTGGAGGA
+
#()!*"+*)!+&)"'%%+%&#%#*($!+%&!*)''&($!*+!#!"*&((*%##&&+$)"%!)(*$*!#!(##)
@r2650
GCAATGGAACTGGCTGTTTTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAG
+
*6@F?&@'&G<"*$(8A=#)F1E>&&3(A0#(+2DC">CE4%#>>3$:.*7(%C!6<H&2$#D/FC;22?C/*
@r2651
TCGGGGNAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCCTTATCGCCTGGTTCATTCGTGACCTT
+
?B%8&H41&@"D:;G:,#:C&9+1=49/=7+EA(6-C;#$3=*/8'>*,A8.@3.H2%B;=F&45'.+''-C9>H@2/;&'@153=+@.)<#9H8C!#H;(3%-7(?:2H:!>8)=G=#)3A
@r2652
GCGCCGGTTCTGATGGCGTCTTCCACAGTAAANTTCCGGTTGCTGTCTGACTCCGCCTGTTCAGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAG
+
%9@=,56:!6B.;E%FD.#>:<C5H>;.07!2.,"GA&#),#&48H)/14094.2?;#-53GE;'0@F+*2'"A-2B"GB2("E02=55G0(#>-<3<9D7-.#
@r2653
CNCGCTTNGTTACNCATNTAATACNATTNAGTCANNACNNTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATNAAAACGATAATGCAAACTACGCGCC
+
*"'&&"%#$%&*%""$&"!)(&$*!*''&$*#((*#*'!"+*"%!+*%!%*#"*&$"#*$''"$%)+!$'%!%"#+$$%(+#("%'(+$)!'&%+++$+"$!#!!")(%!$!#!*#!+&(%$#)#"%
@r2654
TTCTCACGGATACTCACGCAGCGGANCAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCAC
+
73E98G$'2(57=;GB!@79EC)1D$3#?5GB7;>'03?.-&/.7.F4F#%#>=@B5B'#.G#!)#7+=1D39+;.D/@=;E'BE%>)!"?,8==%*@/31
@r2655
TCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACAGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATG
+
F>>@=9AGFDH,.B8A!&/E%D9A/6FE!&A921/?1<B=?/*%D'+FF)##0@(G22B+F+9G%"B;H')68@=6"BG!E*:8B8F6.G>$-%#";)
@r2656
NCNTNAAAACNCTANNAGGCGCAACAGTAACCAGCATAAATCCGGCCGCGGCTAAAATGGNACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGNACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGNAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATCGGCGGTANATGG
+
##)*!%'""%&((&)"$+%('&&)#%"*"!$+)!'#)#"%#)+!+++(+%$++!"(%'&%*#$%%$'%('+"#&$+$%'#)+!()+*$)"(+%&'"'+"'$#*###&"&))'$&'&!(%&$*)**)'"$#'$&+#+&#*$($!)#$")#*)'*!)+"')%!#$("(''*'#*&!*&)+#$(+%'"'#(%'!#%)$'+"##&)))"$!)**()%*$'*
@r2657
TTGCNGAATGGGGATTTGTCTTCATTAGACTTATAAACCTNCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAA
+
E>'@G;#9)'+=/3C7BH"4G>?%!)0#+:C&*BFF0E;,<"67*:E/#);6D+1&:F!4G&%&(C=2&;19&BE'C"'B,<;D"6H$!932A"21E/5'=.;=E;>=>D.5.@!&-D'7G$.=0&:(4.#2366(?B>!%4.3?<.,!,:B-#,@25;94G&H!*"A(?*6-H<G?;#3957&&@$8)5(?/#<
@r2658
CGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTC
+
B2E1'#%0292==%:B72-H5.@F57"@)*A/#55(117AD<7*6AD."E'&)==9E!H3$+F.C9:C8<2@"$BA46<=!4+.$90"@5H!#HD=4A0,1F;0$?*:
@r2659
TTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTCTCGCGTTCTTTACTTC
+
'>??A>;G+C(;9E7&(HB.<-+;?"2(?:D4;>#;-HB@37@1$DA$B6&79$8=**H=0/C$H(.)E'1C8*0B
@r2660
CCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGCGTTGATT
+
@-79D"1(A904:?/2>E!2'$H"-).3ACD//*0?46#,FBG7F<E**=<8/7/-04D<5>(,!
@r2661
NCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCNCTCCTCGCGCATAACAGACATTCACTACAGTTATGACGGAAAGGTATGCA
+
$.DG-A;5-$#"F0<(+):0GEA>.$(;>)#'@/!2=($@41D:B92)E2@@'>?E;8D9@5/E,083-:E0=!)@+.=&0G@33?>H@>G3+88+;H!-275+<75$.8++@B$,!)%@7:03C3-G1.0B!'
@r2662
GGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGNCAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGNGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTC
+
8=889-E'F3/A,'8+4.9&?E$2F#B@%-D$'645=1,2B*90+H7?&+>(0AF"@!G5;G2:<?D2A&$C#G?4%!/"/B*9;-/0A5.!<D14#9856+84?;+:)5E&A&AFF;H#(0)*&-<F<1!,FC7/A<<C:"G4&/>2+2<+2B-$E--C--2/D(6@H)F$G5*>C#(=9D#665?/0+.7H@2;',;6$'%2<0,H'*$E>4:#"@D@<DB'!#1C&&/0.<1941:'-F/0F/.)##26);H1D,
@r2663
TGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGG
+
:4$%5:+,7E)0-(HD:HGG:%D7F?B?8*,'D70<?.;D:#;@4F20575,@
@r2664
NTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGNCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACGCAGCGGAACTTAT
+
""+%B-*<#B17.65:@>C.:7(G4C/$70)%5#00+5HH?-1*!'9@:%>8,61H?5C<!F,1C<75%5(B>(06+145(9/B!!-0H5=7.H1@5-<+(((.=/26%:*=<C%2,6+.F/E;:$1G<)#DB(8.5337BF:G+BG=))3;)()0"6%8)8$A$5B%!E8C8F=:/6%+C?3,:<A:,$E
@r2665
CTTTTTTCCGGCTCANTCATCGCCCAAGCTGGCNCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTGTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCG
+
C;@)3G/(A$#$:F>A&F+9%00)-@,3??C"7=*!:A@>10H/C:8F>8+,;85126B+.H30+73-4;%7;%40,CD*F%*)@@4>'H6GE4#?32<!)728/",=8C%/B<2G5<&96+1-?<5).,:)A4!A6.&
@r2666
AGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAA
+
(,0@-)@<)%@24@-/.(/'9=3E)6AG,+4.G/BC1H#@(%4$<"+-F@8.'&9/?=845C*8.
@r2667
GTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGG
+
(G=<$:#C1$D6C!*4,0F&21#;@D6=E!)-:$.=2'G@958+&"1+%'AG4;)4/6#)9880?9#H.*5#,A(0!72"(*$><>.,CD/=7'&%;2.!D6</.1!EF@-H2@+B!;1A&*"?=@""9=H'>H$G;GB5>1!)8"459'A@7D1<*;-D)D7
@r2668
NNTTAATGCAGAATATGCAGTTACCGAGATGTTCCGCTATTTGCAAATCGAANGGTTGTTGNTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGNGNACGAGTTTTAATCTGNCAGTGCAGAACGCGCCGCCGACGCATGGAGTGCCATATTTCTT
+
"#+)&%*"(&*%+*$%(!*'(+*)"+'()"(()+!'$&#"!"%!+"*+!*#&(*+%#%%(&)!(%$+'+%""$#($&%)#)%&'(&*'#$&'"+!(*$"'+!"!#)!'(&+$#+#*''&+)%!%'+&!'!$&&*"*((+*%#'('**'#)*)$"$+%*+#"(*(&"#+)*#'(*#)%&)*#$'+)(**$()#!($$!&(%!)'*)!$("#+(%"'&"+#(*$%$)'#$%'#""(+*%($!'#%'#))++")+(##(!(("($%%'+*!$*#)#!(%&+&('*'
@r2669
GCGTGTNATCCCGGTGCTTTTTGCCATACCACNGGGCCAGCGCCA
+
G@/+A;:7D16$G"C*(/,><"!-@E.D%@$@!@C(2*'-,E(2.
@r2670
GNCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTT
+
#"'@7A&(G%2';">A)/:>$1:3(FB=7E;!$845"1C;.CE$:.>+<!4B9,#&6D$8+#-/BC
@r2671
GATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCC
+
3*>24H9!,)#+0A=C28!/E>7A%,<D831A"52C,:#4>>
@r2672
GGTAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGNGTCACGCCGCCAG
+
'#'&#$*%+!$*!+**))!'")((%&+(!!("+&))(#%))%%$"(!!%$#)(*+$#)*#(
@r2673
TTNTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAG
+
#&!+#"*$%#"**(')&*(*$!!*%%%!''%&$!$+#("&"*#&
@r2674
GCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGAC
+
9?1A(0$ED3G'<267A5(2;BE=?&$;(+7E>.";?='-%D1',>CC+ED3%(.B&,/F'*&/-)=2+4:?A79>0746*2.>%-EF!.!5=13/D+;:E.)(.,5'*6.E@!''$3G"&D@+E2!8<B#;9;6B:8B-@1(5/"*D;-0,*=:?,!@9AD(26%1$/94'#//"<<>/1.$.B
@r2675
AAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCATATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTG
+
H.C53FA4/-@:@.1;<C1+8.EE=C"3'0.H#-0D%&-(<E'2E5)(+E/7G!*5!B@#.F#138;AH+3$,-+)2=*,7&)2B@!,A-5CC@!&#<,2"2H#7.@&6#'-"&$1'$#1"9:C*DA=A340$>H%C3.4?0.%?%>1#=+#<B6?):$3$:?)<!26+?78?227>9$291&,)16FCB(:A+$CA'='49F!@16BH0<'9D>'E5><C4@4F<:+D%''#-EFD/$B6&0+$D<D*:
@r2676
CCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGT
+
D3GG6G/%99:!1A4(;@B%%>F@><@=5>DD"B/+*=GG>4F-,)*$03@G<.A*A06;%F
@r2677
GCCTTGATCGACTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCNTCCCACTGAGCAGACGTGAGCGTTCCGCANGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAA
+
=?<?8G-ED5.7#,4<E5EB16<"EE-)81HD&?B7#C?+8>;2B4#3!D=>3+B+B#D'FGG&6'DF=4(0,&3+*>/.9*(:59E01)GE6@C30=D6++<,@C("B9D*#8?&5<#1$.BFG,9%E!4:?A69G)/+*E7<B98B;=HE#DG'!;AA:!=5086(<6;7=#,!#C<7=63<B"0-50/GH-BG:=:.GE1A/1?27-1((0.3+@!FH><FG@-1/0<A06F73;.D&*''47C5(C</@D1*!*7#,3(.<B7F.$02/.,3B2."3C0F=@5
@r2678
NTTACGANAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCT
+
%,E7B7&&EG:35&&%(H2B8974":F&34#@,%.(=,<?<0;
@r2679
CTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCA
+
)>5=:>A?5<"3@8"-A&?"50A,C>DG3>7&'70A!%.E
@r2680
CAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGANCACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACNCATCAAANTGTAGGGGTTGTAATAGTTTATCCGAT
+
51EEC2*8+;F%7%1!)@H+A75./76E8*'C<:**0!)#("#E3.'B8:!0ACG349?2E.$9<G9./D)57EC6=.'E)G''8">=-(:7,%D-DG>86>A+*F8#C/#*+,?,AEB0-.$,>8.-CDE>>><"BE7G%,%2?:8&0+-9B!
@r2681
ATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTANGAAAATGCA
+
G"7!@%AD9$+1?2F'F=7024"72?+B>("24'6'>#-!82*F?>/?
@r2682
CGNTACTCGTTCTTAACTCAACAGAAGATGCTTTGTTCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCGAGCCGCTGTGCTTTCAGTGGATTTCGGNTATCAGANAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCNAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTNGATGAACTCCGGCACGATCTCGTCAAAACNCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTNCACGCTTCATACNCGGGTCATAGTTGGCAAAGTACCAGG
+
*5@H>1$.6A,7+<?;B2+CF#AAC+.$:E99A/A<<4=-97:3B=*A+1,F))4@*$.9DC5;H#2'9E3';#7/6G$,C:C76.2%;<C&A5?8&.3.88431H79-64(5>>#+#5.+E#!<,'>!2?>C*$F"/A;D$=A!%$?,3#*-7!?<E"<)9)5$,!A.24')$CCF?#/C>!$9%6!1B:C:@G:DG=+/?';('!:E3:3D#F#+125E>2@>%F;E=2@4.B/&+C5?"$$"03+1&54:(E>77/.&CA$EB&;8=<?=)<)(5-B.-C?&:%B53GB<<81<$H=81<,B**(ED>2;.&842>=%"@%A=C9G13>;5ED0'=7"@8.D/(F-H$/5C@48,/CE0'3$</
@r2683
NAANATTATNCAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCNTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGC
+
#"*"!'#$((*+!%'*)!$*""&(!'%"&&+))&+'$%(*!$!+#"+)$(#"!($#&+'!%')!$(("*#!'"'+&!'#!*%#**"#$&"*!)%!*"'$'!+#!'+%$&+$!+(++$+)'!$#"!#'*""#)(*$$))'$*#)%$$*%"+'#(&%*!'!)+!"+'$'+!'")!"+*%!$($('
@r2684
TGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATNC
+
=$GH=<F(-%4<7A@.2!?&%+0:@A)>5!4?%#$>=+@:,$:0>"%:/5>4=22%3%=83H-">&4%C4=%:(
@r2685
NAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCG
+
#=7B2>@#605H&40BG$4$97'"F/)$BE9'+D59=4=)+H<"9<8'#G:95#8H18#3E')>*#25A7*/C=3;1>*=F-H+3-&=!?B2$;?:/'B-854B<""+>D"
@r2686
CAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTT
+
@#$,/GH8A.>7>)+&6=63E,)2>3>65:5E$E"E06>BD&2<D!"6.=$2,>(<#@E#893%*#.,;A2(0/55&D!
@r2687
ATGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAANCAGACAGGTTTA
+
&-1/!E,&*!G2.$52%39C9B>>0?2=+FBA+"@%-$%C(6E(/HF&):0:1HC%752"AC/!
@r2688
GCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTNTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAAC
+
;HH?FB3G58E&@53:5)%1,,5F,9$$;9C@E?'A'E?)5H%DB>-C>'@A55*%B4:$.&)1-(3<%-?6F2!'@/2%G$19>G.@-$F<@)*HD&>D#-/'&>6G2H
@r2689
TTAGGAGCGCCTGAACGCGCTGGCGCAGNAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGG
+
%"**'&%#%+)&!()*"(("'((")%)&!%!"*&+!*&$)'+&#()"$%(+!)'%$"+!$%)%$"((
@r2690
ATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGG
+
B+6@D)FB4@*D;>:2"8:A"ACA($-'G>GD=3FAA?&%4H
@r2691
CATCAGTAAAGTCCAGCTCTGGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGAT
+
::""9?0HHEF3)7;"B;9/8.(5.<@</8-EF@5C959*152/2)3G%G,>)447+
@r2692
GTTAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTG
+
+'*=,8A!2-,,=2H?7#>9F/C?5)A'<;!2/4'?F&E)$()-6$(!.-(!!<H<>A8,#G,D--;268='F;,?!8-.2!,D.8#(('<%,!9@#
@r2693
CTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTT
+
FH<15G<?D>$02D3+*6G-=6BG55<.";%!+3B6&8"7.@",@&=/:
@r2694
AAACCGCCATCAGGCGGCTTGGTGTTCTTTCGGTTCTTCAATTCGAATATTGGTTACG
+
()E(@7?(@7-EG#'@-F--5(-"1B"H0FA-7B00.?.9?)2<(.C&$D97E*/$?;
@r2695
GAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAANAC
+
,A8!&,AC<$@=(.*!G;53=BE886D&E(/>8=3:1EB-'@9"%)EHF=+/
@r2696
CACACCGGTATCCCCGCCCGACAACGACGGCAATGTANCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGATCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATNTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCATCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTG
+
203E!>?0-!:#92)C656/>"HF"6:G14<994$@%51=6;4#1E@/:15G#"'6+''G38@:)8/6>+-E?4!3C.B<,+/899/(E78((G<&#@7#36H;'$>G.=A0"HH'/2+8&/0F;52D)!82#D77)/<56G5E02'?7H'$!+=3H3F<"%)7"+B5CD70;?=(&!338-0$$79);>.=B-&.%!>/B93='7$)E#&&?$;D%(;)/HC=97)H'8!%:3)87A6<E$);HH2:$!;>.B1#8A--%1&8G.!FE2>E97?@94'9;:H/6E<;;02;/A-:D!$0(+-:A=1CFD<751E*#B!A>2.F$($7'+-.5"#"??GGF;432"267(:;!#88G@<23%EF((DA--(F?!#,)1.8>2@=%E$-H'$4?*.&4*=11"BE-'"++B49F>('#1?C9(F(:3EB5G&+:8A5;+<H";66C;3!*&&8G1#=:0GF7!
@r2697
ACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCT
+
'>9H8D9B386EDE-2(:G3-EEG<=<*>7%AH82A>9E856D/<8)1@H=E-1'AF6)$>AA7?,"DD4A57.G7A52(0,@;@)C6.H(#5'D47#HA,8C.":2F>=/%/0C
@r2698
CTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTG
+
*<7;-*12&<B!;2)D@-=1><2(C5%0-.==)??!"@"8E'H)%"3,2:?,62186=3D9G(F'@"EH7@!4;6&%*$$&?-,H%F$8+.-30
@r2699
TGTGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTA
+
'$D-@;-7H"!G:7AB>D(<3*A,*40<A/23$3D>E(;"'1E5<:7$A4G'
@r2700
CATAATCTTTCAGGCTTATGCGTTGTNCCATACAACCTCCTTAGTACATGCAACCAT
+
;>&B.D10$,%C.+0%D)6?<%5,/.;A)@&D:!;.4#21D@4C7.'3@D3=>6<?H
@r2701
TNCGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGNGATGATC
+
!)+#%&+)%'#'$%%+$**()*$&+#&&)%'*(+("$)(%)$#$!(!++
@r2702
AGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACATGTCGGCGGAGCA
+
@;H,9*0E55<C%3"76!CE(=9@D*&&&::$B$G+2A/,3=>)5156!AF=;?9&.@0D4/?<3'(<#E>(19??A:!$8+6258>")'=
@r2703
ANACACTGAAATCATCGATGTGAAACAGTGCTACCCNAACANGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGTGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTAT
+
$!+*)!)$*+#&('*'#"+(+%%(&($(!"'+)')(!")%"$*$%$)*"(+(")+!)&&&&**%)!)+%%('&&#$#(($%"&"%!)+*(#"()*'+%'*("#'+'!)%"!)$""(''&(*)*"&('*)$#"+$)$$%'%)&##)
@r2704
CGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTT
+
B55,:$5,:+5'C@/96>&:)8,?71561**F.,$*-;*6H
@r2705
ATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGNCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGAC
+
<4=-'#C&7@,?9?)/!43.-07<<B060H@!;1)FG(C3<*#F<4;%)=>C?#F7.G2(.-!4=1;@99?>-%H"H">$G->H%32)H3+D32?5%-C>G#598!9+)=H0,=A"C::$,7HCF"%&/%2-2+?(;&>);B%<'++E:3H-.<8?+4"%,2.D+9<?08:)B0--B;<(5+//,A?
@r2706
CCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCA
+
>0'G-=@)AH@+4)9(;3F@3?2?8</G/9G*%&C'.-"HDE110:%@6'8@=+
@r2707
CAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATANTATTCACATCGTGTTAGAAAACGATAACAC
+
-)D51),FFFA3:D'D;*6)G>/9)8@$$*1@/A.@39G62)5F8>84"%;AEF#A$E%5$H-E7?+1>E#(4<<$-4C:E!"B4HH;3F*3:5(>*';H(%!6H<38-'>?;<+,8/G,3BDA"F(&EFA$==D*>*E&AFD/38=/)?G?G4?361G;
@r2708
ACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAAC
+
:@@<1;;2EG>#2?6AE-&@>(2E6)8*F.0"/#87>/"C5H1@#0;0GH9GB3/$/=6'5921@%:5<$(FC="<."<FH!1!32>#>.8D*"H:C'!6E)01.9'@;<2#5-AD:B+:F*=F?5>;51=@.!<,,"..7""!>@E"*..-8//3C3214.3
@r2709
NGNCNAGAGCGCGTTCNGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTA
+
$)!(#$&&'+#&&&&!&%+()(%&"$%&#"&+)(#!')&(#((#$(#(('))#++*#()#(!'+%'&"#%*#')($!#&*##!!&*!%##!$&%$&
@r2710
GTTAAGACGTAATGAACCANAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATA
+
G)1:7?GA008+%@:&-BD&$C!95G$?=$9H-E40D1++8#&7/E!"?4E"E2)(3!29%39+><0$
@r2711
CATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGA
+
98)=+:5@,9-4<25G7E+4H<D!C58+=&G9"(G2E0:4'"($D<29B@>"*F1GA>0:
@r2712
NCGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTAC
+
*/&'(B"&>B794@D=!@45>:%?H3$HB349/BH#8.>41@#!!E*$''<>5%3*F<:H((9
@r2713
CACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTTCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGNATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACNGGCCTCGCTTCCGGCAAAACTCGTAAACCATATCANCCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGNGATGGCAGAAATGNTCGA
+
B!:!!98F2&&>B82-1H=H452=->22B-0,:@C&9190F#-7"8H9,2;%:)>15.-F64&BE#?H+)"F8(9--+02%7#BC?(!!1-.7CH3!B0(,4>(=?=?!3EA@!C89$;D<H#3;A2"D/+@(0#5B1-D=-=G$E=42-5$>9;87@+CDC:,B$(3.$(40#>A(=49E9#3'+6669#+...;FC@-?A@.>3F!5(34A#?!'$C;B41B9!4"66DH=:C@:&=$E0;7@7="5>63(,@$BD6:;H%?70;@#3'(#@D!/-@(E1B#)@
@r2714
NCATNTCCGNANCNTTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACCCAGCAGCGTCTGTTCATCGT
+
"'**!"$$($#!*'%(+($'!"(#(&+'*))&!!""%+%#'($&)&$'"#&+)"%))"&!"$(*'+*%''+*!()
@r2715
ANGAATNATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGG
+
&&((*"$+"$&$$&%(*#&%**$&&+)($++#((*(($*&%&!%%%%'#&''$*#$$&&"#&%$
@r2716
AGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCG
+
+G,8945%84DC7%A7B?<0@7#!96:C(&H2;;7<1BG09
@r2717
CCAGAAATTATTAATCTGGTGAAGTTTTTNCTCTGTCATTACGTCATGGNCGATTTCAATTTCTATTGATGCTTTCCAGTCGTA
+
7A2:%)#CB"#$B727&!-!FD,CG5''D(F:?<@(7(DH.-!//&F9+G&FD/04-7E:#04#7<2=1$9.4%$8%=F*=GC<
@r2718
TGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTNCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGTTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAG
+
*A4;H)2DB/>DA(0";?@3?=!!?+<74D0+..9=*$B#5*#/6F=.5=?--)%*%B#ED*56;.-#=?AA!7*$59734G4(E/9C5)A@D*C%%B/5;2+:;&:=7+?">C>+?%8*4#:92-FG:(B5>6B8"&B-!D5A55?H;>41>=D;'$<;/?E3'0:<+-30>4/*4E3<9+4#6-#EC8G:.9-0A=:CD-@,054"#2*%:=!H*H3/7:(<,CB>C:':G@.#)3<14?+%1'4;F*,*/$6-9:7A5*)(8/88#<AE%=<,">'2'5;9=#%$:)#!%<G.99=1&/!)
@r2719
AAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAA
+
-E&G$/E:=,,>A!*#$>1=G;GD1C$8#>7;+CC(8"0/%.E9$,H-#72$/0<H,74(,<!5!9.DA6G<"3;D,-$F/<48<4B:AFC>38A!--B$C4*$?GHF2=3(G:=#0+1H9,8>&853(%*5,3)2:/,@88+;4)HG+7+'?%7-F9&AD(/%>4,6A*C1@*8*0HF./=.-BG(!"H60%;-4G;&>AD<A/
@r2720
NGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCC
+
!;A)A+@#-"&C9>(7$C'C5/+3>4-D;=D8#1-+D<)DFB#0A0B.C!G=3=36E*:,E(<#,)H')<.;;!4=F
@r2721
GGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTNTAAAATCCGCTTCCCNAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGTCNATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTNACGCCTGCC
+
-'4%*HC7)=6,/"!*HH.D3$:!:#"7)4#F#C>!7FB2<=D,)A1G)+=5#=68B.A;+*.#H&420B+@.@&,9B8:8F=(8>F'%-5786G"AA;G'H44+!$&B+.2"70"4:H!'$+4'&E)#)"&7%85%A#=05.BB/6)CB?3(8B0!4D=3A-*$5&,B8<A+!@-&9B'<;,7!4H"B#6>GH,D3(.)H<BC<?5:*C+9;4AAB>'%:93:54<<:=;5"$)'(A=2%?-(46F#.*&
@r2722
NNNAAGATGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGC
+
"!*&82/;'027:F8-'9:EB++>9,F?!G@7H)C*G/@!&>*+72*4531D90(<B9#,4B=;;F<E69@:!FCBF,F.#%=0A41="FCB"
@r2723
NGNGTANCCANNTGNNCTGTCNCTNATCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTG
+
!&!$%%%#(*%$(#*!$&)%*!#&!%)+$&%%#!(%(*&)*("%#'&*"!""*+')!'"&(%'"!%)"
@r2724
GTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTNATTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTNC
+
352;GE5<!'1,4:!<$9?70*F9CA!B@F6*%:6(EB:%ABC,A-1'$@?)-9@F10B!#;A02>459A!2F"4$FG?(."*6B)'A90:/%C;"7919:#3$5-!*=.&F*1/."2<'=)E47/B@?6G+5@>696)=G"?D52&>62<*B8
@r2725
CTCGATGATGAAGATNCAGACTGGACTGCGACCGGGCAGGGGCGGAAATCTGCC
+
1>!;8-/'*-03BG!4(1780,%2&D1A*?1$9;5&&&&!2+=CGBE:G0F"A5
@r2726
GCNANTGNNAGAATCGGTATTCCTCATGTGTGGCATNTTTTCGTCTTTGCTCTTGCATTTTCGCTAGC
+
#!&((%&'!)+"%"())!""('*$($!((%#"*#*$(*+'&()&+#)$$($**+"*%"")%+()'++*
@r2727
GGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTNAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGANAAAAATAAGGCNTTCCTACGAGCAGATGGTTGGNATNACTATTCCTTTGTTACAATGTTTTATCTT
+
&+$'!+%$''(%%#%!%#'*%(&%$&)!#(#"$()"&"%%)!&*#)"#(&&!#"'$'$*!&)&&*(!#+##"#'()!")(+!*)!&"%'&"(&%(#("'(!#!'&(***!)$$()$&%"+&$&($%#$*'"+!"&!!+")%"*'+!&
@r2728
NGTACACTTTACCNGAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTACGCACTT
+
!*##)&'$%$!%)!+#'&&'#&)&")'"!#((!*$'%#!*+)+"#"&"+*+*(#%!(""&)'&*(!$*("$%&'%&'%$$"&&%"$$&+'((!*(!$!+(&)*"'&#!*&*"&'*)%+""(!'))''#'(%+!!&"'('!**)+$()')&"+
@r2729
CTCAACAGAAGATGCTTTGTGCATACAGCNCCTCGTTTATTATT
+
E5H'B5#)@.05F7:')DG(.3C-&:)58A*,7*B'-C8B6=6>
@r2730
CGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGNTAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCANCCGTCACGTAATTTACGGGTGATACGTTCAAGTAAAGATTCGGAAGGNCAGCCAGCAACAGGCCACCCTTCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGNTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTC
+
28@/8-#A+"+#=90H47$D8@37H6*)%00)G+.212$6*1)$7B.-C463"$CD$#DB>HC,BA3"<3+CD"C'E"8(G!#;99?:7?F2B6/<1,<5,7<E==?DCBD>186C(08HD?G!#@<A:9;D8?+G"<%'!GCB.H?!/47.?16B90;>@6D(F&4E,-7GA,8*.1)=,)9(C4329/5563;,#@>,/.BB&6*::F<0*5=%"*>8#1!F0"/;6(D8B47+;=8@*>(H@C#C;F)$D1.257"*)/&H3853<.8@,12G:1;2-/ED0;50&'+-14/1-F,(9.?#43G2->;@8>F:%/H7AF-9*-;*,/5#C=C?BA>#03$H
@r2731
CGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAA
+
H%?%F*><D&D,3$-F,*247?E/,2%'B1>9$B%';-8!(3.+E$!58
@r2732
GGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAANAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTCAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATT
+
8':E:6-E*2;6GA7"#6=A.077+C(5!<41$<6)E;DF00'E2E<#5"D!$+91:8'D1=17!G93124;'6&<)7:#0A$!?!5>"B+))4!)="8C:8871H+4&7?!B)0,1FD>0EA'>=?F8F:*%A&94G73H7;,DH84/$#G2<B8AEF89*C3>941"/D!8=%;<-F6:35?"92/G(>.'6'7,0BE*"D&$!;%H+28389?395CCF83;,).3*A,!!%BD&2%'A4B<((%=01>9,5!<9F!2"<<=+EH/!:10E,5#+*+:,#900A-=1DH+(5,?2&--:&;,/404"A9,5="7;D135,!A0CCB(FC.HF8D<5>(3B!H&/%6;+,BHE,43>;
@r2733
TGCAANGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGA
+
9@$7"G+;+'E,"0%#F2-'6$>H&9>)(15F2-$/#G'&>2!?6DC"82>%G:'H+:/.D@0F.H,D,#/0!#9?"&D0>>)D0+<3(H#D=
@r2734
GTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTA
+
$>F$<(38-,;("$F.71,@&?%5A%;0E77C$#;F#?59,"+
@r2735
CTNNNTGCNCNATGTNAGNNNNTANNNCAANNANTTTTCCNNNAAGTNNNNGNCACCNGGCNNATANCCCNNNTNANNTGNGNA
+
!#!$#$"#$$"$#!#"#$!$"##$$#"$#"!$!""$!""""""$#"$!!"$!#!"!#$!$"$!#"!!$!$!!!"!"""$#!$$#
@r2736
ACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATG
+
9D9HA33)FC'51838.-;16#D69?!:27C,A4+E!:4,-2/3813#/"#,""5D7);$2%&8?%//342#&>(&%&=60.
@r2737
TGGNNNTGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGC
+
%'##"+'!#&!%#$'!#)*%!"&!&%#*'!)$!*"$&*'**((!#(&"%#'#+%$
@r2738
CGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGG
+
#HF4AHA/+!.'2#:CC6H/$C,$02>B:$7"/?C4/?E#-"-$#&A*1=8F9$'DHDB+45,:*E:'6A!G<$#45=H4&F="8C"8"AHF%?+%5=)A+4FBE:?G>(H<,'.5/-$1<-4F"&5?42#&./F!0!H%-(E%G";!2>(FG@/%7<-2?7("AB-@7C-!14'11
@r2739
GACTCCTCCTGCAATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACNNCCGGGGAAGCGGGGATAACTTCATTCCCGTCCAGGCCAAAGCGGACACCTCCGGCANGCCCTGCCTCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAA
+
3-495C?98?G!(FEC21G:!(/H##-;8%)E:?2/--9,ED7&G&660'32/-@:A'%4(;,-9A0D#(/&C5<C):21$0&#,(+1%@@'-A<'E1$'=,#>E6C7G44>.?=8$</9)@?49HA7,8BF(457/&?&F1;E2-<%!?1(/4>29C80'51?/C,-';9;#/2028;@#5+*::!&2;4?>>@<C(6463;A/+1('5<1-A+G.:%,"A?+"%&%D
@r2740
CAGTGGATTTCGGATAACAGAAAGGCCGNGANATACCNNGCCTNGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGGTATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAA
+
+:1A*65@731/=!)3E2)!%3>)<78".95G:C73=8/HG;B/.&88!:/)'"&#!%,B+.G,)=6$4-<G"-=38:EG#=5.+0)98$:C/###2-A;*>A&G@+6@A;!*%<D8-#."0.8H35*D;1
@r2741
CCGGCGGGATGGTGGCGGGGGTATTNGACTGCGCTGACATCATCGCCCGTGTGCGAGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTNA
+
?"'5B0?)'>"?@>9G>?(0A<,637-=90<=AE-6326(*(9<,3+$;C#)G3E"HC<=H)$$&171>C'0,;,/CHB*3!B$1B!@+'F8*B/;6D<;3=E,)9+2A<7D,+G?9-"/@0("6.10"*:7;*:!!<"F/C82D8/!:3"-@">B;'&E;CC)1AC7D16(1D,.%
@r2742
CAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACNAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGAT
+
3$)@,,,<0#*1>:)#GC7>%(5=76<D/0,E"1$:*.0<49B.93-0.?C!;5?#*!H=,'-5@!"<14&+D:27(C:$$=.B@:15<37'/7&773&2B.-'3!)(6!)@8.FE5."8*$E%,D;$)><")D&.4<G.78$GE(6887
@r2743
TAATGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGT
+
&%#+$+*##+!(''#'+$""+'("'!*&*&(+&$!(+*#"""*+*!&$(*%)+$+!!*$(''&%!("%"&*&(#+)!
@r2744
GTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAG
+
C9>**G5;H4?5/8H/)*<'89"#=;51>(CE!+%2%F'(F!:.&&E>>55=E%)@"/=-.3(HA?56+F79;4E%EA?)@)#HA+0EE&-)462$/.D-F9!481,)B;'?2>C--E?$%.DB1:569)6;ED"!DB-
@r2745
TAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGNTAAAACTGCAACTCAATTACTGCANTGCCCTCGTAATTAAGTGAATTTACANTATCGTCCTGTTCGGAGGGAAGAA
+
5H/-(0(42+">-*1B?C)!5*4?G9>71<0H28:=,-#/A>7HF?30-FD80EEA,>D%!"B;'26D&68,"8-26>H1$/E1-<1@A!0:/1)>;#?"3E>59A@.G=<>)'C9(9&+>>H*AAB0!;@.-2/E7;33/
@r2746
CNGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCTGTTAACTTTGATTCTGGCCTNCGGATTTTTGACCGTGGCCCTTTTCAGCCTGG
+
4@:A5(3:2&4H'+)6!)%4A:)2'C92=*BE%H-AD"$.$H4@,EA).37B7#-8;:4:G?&>DA08$F?AE(:?HB.BD2=;<F4(5>@G(6*9<4@@8,<9G?0HA=$H43>?H4"20,#/+F3.>B.
@r2747
GCCGTCAATGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTGGGCAAAGC
+
A..#"*,31@:*%2=7@6<H&;==@CF(CG>:)E!"H4FA2A#$D"GF'#C'4EC&6-'?2(7+>,4E0=-H79@?1
@r2748
ACCCTGCATTCGCTANTCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCG
+
C43!F1H;6$B.68;AG#>,=5;?F1,F4A9+/5B2%2!4+C-90(5+3:$F/<G+E&)CA2=(%@*(-A64G94,@86'"/#*C?58-
@r2749
GGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTC
+
ED)':442#8!-&@C51#*)2282C%:(:#2//9$F!+<C
@r2750
ACACATTTGCACNGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCNGGTAACTCNCGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATAT
+
>H6/@:,B1>?'.&"#$H,&C*+</'%>G$.:+01H0.H!A;+7;#')+A-H!%7#+4G)1*7%$>*=:'3,E%(5(FG*"%846)1.D7C1*6%6E/E?4!C0=?)2<(9?.88C%D&$/B26+A+FA>&#/@3/E2D$95(
@r2751
GGTTNNGCCCCCGTTTTCACACGAAGGTAGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGA
+
&#%(!+$&('!**+')"#%+()'(*%%"&$!%%"''('&)**+)&#$%#+(#(&*'+&&*)$*)%"($)"+&#$#'%#+*!")"'#*'(
@r2752
CATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGA
+
/5/$DC>;89/B6B7@$H2HHEAH@)=/%)CH!?1!3=@>D-G7-B59&@?,?7003"*2B'&;G.E(+("9BE9/'2#'=5/&D((1;
@r2753
AGCAGAGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGC
+
DA23+):?8-A<--,<B/26;?;>$2;%"2D$=-/9-DD*+,2B&CG8>@(*71D#BHF*49$!B3G,A=@(!!3B/-'G@28D+C1/<"'18E*,=)/E/-'HG(*F4.
@r2754
GTGCGCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATG
+
%,?&+7-9FD#@(<02$=E%/()C,AAH-"/C4F?0%(-.B@+?#*%7;<B-?!1
@r2755
NANATATNANGNANANGCNANTCTTGNGNNNANNNANNNTCCGNAA
+
"!!#$#!#$"!"$"!"#$#"$##"##!!"!!"!!!$!"""""!#"#
@r2756
GGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACNATCGGGGTA
+
>"3*7'8E;H)@$E6B&3!9;2D<3DF@%#1:?FAD"CA/):(3<-E+@;<,1?1;&=:+#5"$'(7<
@r2757
GCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCG
+
=AEE=:@:3%6H52(<!7B-=G=(+H!+G-7!%H#G*3(#512!#/E*+1)>3-3E=1""G5>1.'F0(FC?B/#A1G)&6BF1"AH91G@BHFD%'&F'(
@r2758
GTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATG
+
)8?($G!9"'/=?#FDH"91;'*@+)98-01'!C8=<8D:$(2$*04)%&%((?3/1%C/E3F&8=3F
@r2759
CCAGGTGCAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAA
+
(@'G%%@?G@8*A'&-C!20'!A7:(#!;HF0$3CH8;$<5;/(?:9A-9D3A&%>+20)"4!01/A.BA&.,<H4?@68$B
@r2760
TTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCTCTGAATG
+
EB/@6BB!/D#((0E)*=C#%C#?A&31H;4C>?>78;(9:(F81.G!1
@r2761
CTNTAGNTNTCTNGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACNCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCAN
+
$(!$*(#!($(#+&)#""'&*))+(#!$*%"&""((('$%#(*"+)#!'+)&&&%((%&+&$*'"'%%%(&%+*$!*(!&+$+*#!(")'!&#+&*#($*%$"$%&&')+)))(&!!#*$(%&&*&*'&!%#$)('&)'$"($)'%+#"+$!+&'&**!&!''+#!&$*#+'+$
@r2762
AAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATT
+
/0.:/,>A0D4H%!+=>'=D24>1!##=:9A3-A@925D0B;:'>'5+&!,2!#9,.%8HHH4D
@r2763
TGCATTCTGGCTTGAGGTTGANGNTAATTCCATGACCCACCAACAGGCTC
+
++'!#))'"!''%)#!($*!!&*!'"'(+*#!%&%%)'#()+&(#"+$)%
@r2764
TNNNTAGTNCATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCNATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAACAGACTATATCGTTGG
+
$#$$"%*)!)(++*())##$#*!$))*)+#))(+&(#$!(+$&*"%(+)#($%##(%%+*%%!#**'++)$+)#**')$)!&+##(++%$*(*(%)"&$)($')*)&"'$(%)%'#+!+"(*$!#!$+)*!%""&+&#$%"!!#$%(##""!*"$++#%%'*((*('"++'
@r2765
NGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTANATAAACATTGCTGAT
+
!F//B90BC7)DG)(!+,'!@D@.?3$+F'+9%D<>9FH0-FH),,6256)GD&1&!F:-B":
@r2766
ACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATT
+
=:5BF'+&C0D1%)(<%:-*5<:-:+6:0;>GG@$(H<H)F?C>=&;0,.?H2F&1;>F.5F-D&%$>$5>$H
@r2767
TGGTCGTGTGCTGGCCGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGCACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTAAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGATGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGAC
+
)(+$)*++'+*(#&&%%')#&!$#!#$()+"+%'*&!+&()'!(#$+&!$(*$&&*&+"%(#*!"$*$&!%&'+#)&()&#$+'$%!&"*$(+&"($&#$+%**$#'!"(*!("&!$#%*&!$)"&#%%$"")'('+!"'"**#++'('$+)%#'*&)$!(+")$"#+)*!$!#%$+)"+&*'+!&'*$''"%#!#%$$**((%#"&*($)++(+%&*#'!%("(+*$!&#$#!(+&+"#+!#+)#)!#)%(*"$*$!*)%%$!!
@r2768
NACNTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCT
+
):<4"F5FE$>$5F-B+C4493!5@%3>%4$1,7H)F.9$+44(5+$:D6!)$#)+";GC?'$%&!-!@'
@r2769
GGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGG
+
!''&)%+&&$!*'%)%!#+#+$*#**"&#$)%$'$*"'#*&&#$))'#(*!'$"&'&$!&&#*$'!#(")&(*$*!+))%&%)#
@r2770
ATCTGCGAAAANTGCAAATACCTTCCAACNAAACGCACCAGAAATAAACCCAAGCCA
+
2C1;3@?'>DG3;(0D?,!B:8>"!)4#6"CGDFG!/7E?B*4:C-$F$;"=+A9=3
@r2771
ATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACA
+
1.79E!/52BE8660-B>F"6F)&G4B$00(6)6!G%(H74"?(2%?4!6C>72G@CC8CE)>9+1D0B94C%&",88F75*6E&/(?'AA
@r2772
ACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCC
+
::"&().?63FB'"<@C-"05;@27(-;0($/@F1+;3843($.>+7D'D:?C?**:,C
@r2773
GGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATAT
+
?A61=1GF!!;F:@?&5E0'H=%#*HC5=5@D,#"/)+-7>-#/+$2H78!?!C#.&-@:D@!*FE&#</6D(F!;"(>/,6
@r2774
CGGATGGTGATGACGAGANCTTCATGAAAACCCACGTTGAGCCGACCATCCGTGATATTCCGTCGCTGCTGGCGCTGGACCCGTGGTATGGCAAAAAGCACCGGGATAA
+
0+<)>;%<H5F<&A2?H2/5<@3<%."<9/<?*6("F%&@G90>177:(8<8/#C"/538#%6-A/'C7;H='%-/'%(D;19D3*0#'0=='H0$CH%<A;"0#>3?@
@r2775
TCGGCATACAAATATTCCATGAAGNTTTATAAGTCTATTGAAGACAAATCCC
+
-H&@/,/1(C.*H5.&=3*);1GEH3(=9+E;9!H!&#H/A%C/H;'D,98D
@r2776
AGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCT
+
)0#&65EBF;0D';?<%63;'(F$C;-D(C+6.:G:5C2(;@
@r2777
ACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGT
+
:,E1).6=?"=,B+4/H:+"E*@G++8)/@8?&1DG"/&16.*F:,";1)9/)"'
@r2778
TCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAATGCACGGGGAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCANGTCTTTTTC
+
773$%F3=5>68$4@<@7<(-5&<+9'E356A&7$%>'+0H"-.EH2%H6E42-?58'26/@$0:H<3,<F%A%&8'(0.E'5.%$9>$&*+=#=%>DB/2D#18)3-%0B!)#6<@GG/3)0)27$207'F%G$*41#9A;H9FE0>B2>#C.E10*6%9E(7?$>+H,2.#&DE@+G
@r2779
CCNTTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGNATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGANAGCCAGAACTCCCCGTATCCNGACAACGGATAACGGTAAGCANAACACCTATTTCTCCTCACNGGATAACATGGNTGCCCAGGGCAATGTTCTGCCTGTTCTNTACGGNGAAATGCCCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGNTTTATGTGAAACCGCCTACGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAG
+
*+=;,A#2<9/A!C-*=,/;<C)$C,F:!?8<&=!?0A2>AC/3!<D!D-;;,8"D$H*/+>4:B"7"5*33/@:6&E!</G1"?.-86FBD%9:E)9*-=!&'+'D%"3E9,F"$?=+660F#1C3H91<$6#H>08.=EC.C5265D0GB'"3.)'1!@H<?=&0FB.++/*+%B7"C-#:<"B2+?A4%=C&0-@$%*?*G;4(A)E"$0*;&F<!6!%.<."210(DB!B#G;B)3*B4%;:D$(27E.9=8H<:C$$4B>*,$($C#B#?,F4+?B<<-7,5)&%$5(@,5:77%+6ACG?,!?5C';G'H54.:<B8;%$:%@"8,94H#:((#B;4)D=BF>H77/"';8(?/B2B1
@r2780
AAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCT
+
??E>=?-699-$(:44"EHA61FC>8:FDFB!#9/?%(,-7-9:;"H,+-1,#,3
@r2781
AGGCCAAAAAGCCTCGCTTTCAGNACCTGTCGTTTCCTTTCTTT
+
+1EH$,'FB?#?38A%'%<H4)=61'76;9&;5<+-;#2#A)(E
@r2782
GAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCNCG
+
HF.E?:&'G8/(80*)/F%+9.3%+&-'&40(%#,>D=#A!07((
@r2783
AACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAAT
+
*B<?:33G796,/A,5>*F,!A$A(C,H1(4>@AD5@!G)+08,E#+1@BD+2)84;H2!*><(6%!#*%)'E#:%%"
@r2784
NTGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAG
+
%-%C#;=&G4015!;.3!E';?5D6-'<,(D2F;9A,$-')!*-";;"'#603#"@4+>20/;3&355#'C9@H0D-=2F
@r2785
TTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCNAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGNTTTTTTAGTCATAAAAATCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACCAGTTGTTTGATCT
+
1;*7<&!/0,>E;G$9E15)4>&2;-8FD;-57C,=;<?%*62E!<,,-!C$0#9#"!@<<86)1&)1C+-D9D+/>'A,%8:B7::3>13'>),4>%7->/5EA7E9BE$BE&,0G%'D&;F.'AC+0>%F;;F7;*#A@6)=@D4&%.G3>)68:(E5-B6-7$-!>$F(,7E5$;BH!3,B?:"<33*@B6B-!F6>A60&33:?E&&+;-<=F3($B3E$H2F78@84:'
@r2786
CATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCNGGTATGCGGATTCTTTGGGGAGATAGTA
+
,%?6?#&(-D">C43=FG#2:&%H2/+=":7$B/CG;FG2FD);>94!4/312B=/9"@6FB19?5H$=79,<CA@:$54@A#F0H*A46*HG#;1C5=*!:4,;=5154.14"G"<?;:D4$&(D#'2C)+)%>1/9-%#2;>
@r2787
TATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGT
+
F/,;5B!&&#7;-1D-)%(F1<9H55)19(H4FF,)B461206:F,;)<8@.6
@r2788
TCCACATGCAGGATTTNGGAACCTCTTGCAGTACTACTGGGGAATGAGT
+
:A(&;G<28@$3B05(>G80$23GBHGE92:G.F$%#,50.1=)B9A3B
@r2789
NTCTGGCTGTCAGCCTTATGCTCGAACTGACCATAACTANAGCGCCNGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACG
+
!E?><6&:%H5"%">%27B?$93-%)7BGD!H4-*4&'CB<7<EA,8<>)"B#85::?#%9EG.-=9<*?9D(?32.>FC4DHH#)B3!D9
@r2790
AGCATTGCATANTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAANAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAANGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGANCCGCCTACCTTTCACGAGTTG
+
,F$&<5=FF"+@7;;62=A';#:<?.E#E*H(G1-*D#9=D8<%'"G;8!.;$>+/>7&2H&$57@$=6F#$8'8#D5H2:E+2DG4;!045;?5G'F'5,8>H$DDG1%=59?,@396G+C!#+4%:C0:#$?;B$.5F2:!-#57&A#88>1&A<(**<3?/B:<:(F*B6@1!$0%6H:8A97>!DA59F1,%GF(
@r2791
GTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGANTGCTTCGTTTATGCG
+
>'D;C"";7077:97*2071"@>2&:"4"#26#92249=A99<8452>8/*%$%,>&H3+!*F)1>)8"6@;F1)AE'B3%CE>;!ADH61/63$!=?5'0E)E6A0.B7+%&(:>?+ACCG:B7H'D?9938)3/62'52;HHD1#/:%H5286CFG>A"3:+9F'4;:,:+5CAE,C/7<A*5&GGA<F7>3&6-&/&08;A/H)82&(;E3F?7#G'.!@H/>HB7D9>@-?),=41H$6$F!HA"6,)."=';D!6G.F1A<(A$H$&)G9?@<D#<1=!/#/H
@r2792
GGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACA
+
$8>#&HG+8#7E1A&=7<$=4:B)H/B/</;AE!%?)=(.4.F34B;$)&*;,??>>&9+AE0*)8,-+@FA@B)9!
@r2793
TTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGNGACGCGTGACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATGTGG
+
+->%?D,5C2793#4-1,)F6!B@=.!+--@)!@#"E984=*4AE?F6$)5:2@/D1,(>,,CD7<)6/15<7(()2G9!8;%!B4>5,-">+,"6G/("B()+;!0E01,63);)!+<2&??C,%CGC;F?.-"9%62E!*;5C=,F(F&94.%)9C"+GDE3:%A'%:/4G-%$,7%-&%CF0&9"<<9DB-8&*7A"56!<)B*):D%*5$&#H<#6):
@r2794
NTCTTTTGTGTCCCCCTGTTNTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCGCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAATCATGCCGCCTTGCTGCT
+
""</D+>:G(D27!#2>5<B#+7=EAF,1!G/1=7+='98D1'&947)8?4>>+""F-C$8):$/.0(.2;&12AG-F&28.<B8-!H3%:;/F0'8/*A?44:5DDHE@'G;7/2+"C3D<@32D'"57E&B"*A5)7&&6)95<
@r2795
TTAAGGTGATGCAGATCAATTAATACGATACCTGCGTCATAATGGATTATTTGACGTGGTTTGCTGGCCTCCACGCACGTTGTGATATG
+
'1=@-D&:!.DED>-G<.!*@)D.>(6AEA#5AF!$&3*>-E0;2)ED6+??96H?%$B13>.19H;&F#2#?+"E>='=<>-2-,.D$
@r2796
CAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATC
+
C".@6=@#F=-2>GF!EDD0:G&3>9C$8)<*@>C?5763,99&?/:08:A+#*.0/
@r2797
TCCCGCTCCCCTTATAAACCCACAGGGTGGTCNCGGCACCTTTCACCGGCATT
+
302*/#(##G%F:D00&-/:98=D:@4>,-&<:6228B7GA2+;$9("C1,@2
@r2798
CGTCGTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGG
+
'#"*#%**+#%''*)!$")+"!#'"!+)(&"(&!"#$((('"('"&#+""("($(+(%$#*&*("*&'(!(()*"!"*)"*$('%()+%+$&!+!+
@r2799
ACCGCGGCCACGAAAGCGTCANAGGCCGCCACATCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCNTCTGAAACAGCAGCGGAACGGAGCGCCTCTGCNGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGANGTGCGGTATCAGCATCGCAGAGCAAAA
+
?E1(/G&4C>8G,H8+C#&?.0'%%3(.'/.0$7@F+7):0F/DG6D7"";C.CA<G&'.9$476?=!;6G*//D30"G-*;4%31!F3D7G6?8*!/0'7=E>>#&>437?FE2&0"DH..<3#5!5&$5.D53C?.GFFH-G2>=C#!:99::'=*?2#14,>"&H5/:06#)AD)9(%.*&-#D!E(&%9=F!H=$)$7<%?@-DC,@C:(<)/"4>A<@1@(68+H+0#;:.%E-;45'C;90$::4+&&F?/*1?*EC*5:H7;)7/%:9G'.C>"48#73'-G6%!/78,(F!4+>F,6H.@?B75!
@r2800
AACTGGCATTCCAAACTCGTATTCGTCNAAGGGNTAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCAC
+
+)+)+($*$)!'!((%!*'+(!'*'"(!+)&$"()!!)$!!&"%"'%"$&+#!+$#(+%()!&%%"$$%+')&$$
@r2801
ATAATCCGCATAAGCGAATGTTGCGANCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCNGAGTTCGTGCT
+
DDF&>2C5:9?!#@,&>G5B780&#B0H:>$0H7F2:</%!#E%0$))?6>@>E/C?&&2,'<+A:0/-%#;8$9BE-314%=CEG?&8BG=)59A#*D?G&FF'97@4-H,2,0';*:8@C.4++,/31$H2<.20B!3D@".GH<:@!/G.';#F(
@r2802
ATNNCNGGGATCACACCCGATGGATACGCGACAGCAANTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCCGATGGCCACGGGATCGGCGCNCCTGCCG
+
($*()"&$%#$"+!+*%$""''#&("$)'%&+&&!#((+"*&"""('+&*&++#"$&&#%'%%$#!#*&++)*$)(&"*")*#'$&%!(!""+(##$(""(*%&"#)(+(#%!%"(&*&))%(**"$!$$""#
@r2803
CAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTA
+
3/"6:;8A4=5H%95@#H('5=*6-73,<BBB%3#B!.!/.+E:15B(.<*23C?F;B<43+>4.7#55/0E5>>1C-(H55==4>/;A0+(7'H-"#0F<-0!!?5?.67)8EDA/><%)3-/00&=18>8$4$!GB>$:$()48H*+5@5D!C
@r2804
CAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGAT
+
A4;>7=<6",F":04)(39!@1:*/G;H&<.A$?>!A)F,@.7G#"%C55"44C3-6=<<D6B(H,9-!F70/.5")>E*6,<+*%4)*-;8CG><"9B
@r2805
GGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTANTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTA
+
51AB@!.=7F6?<;)$+FB>;&#$!-.>><E4+4G=#'076F)2=/5B&$H$;'A'")@.%*1::,#/08?H@/2,",D2>*?7521:C!G(;><.5C1
@r2806
CAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAG
+
/;"G'+F%GG3'7#-6A&E&)F%H(*;D2D?-H6F9),?*(-<B
@r2807
CAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTNTGGGATATGCTGACCCATCCGCGCTNCGGCATGGGG
+
-B81B-@@80C3(@?$?B$,H10";=62+8(C;;@=H?).'>D.>4D4."3B$$1.;6DA,C7"B#"<7B?&;?@>BB!2D>F5:+=!@!D":,E?"EA&,-
@r2808
GCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAG
+
9?6=@-B0@9?-72#F=D+7>4)F5((*"E:C4*!26,8-3%?7F,1(.!(81!(>$=B1,CE*;=+*1A@0*=,$B","E%)9/E10#=F;:8?>E*
@r2809
GACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTA
+
H=&//6@:HH'B@E'8D?40)F#-?!4,3C2"DGC7H&:F/C$
@r2810
TAACTGGCTGAACACACCGTTGATGATCTGCGCTAGCTGCTGTACCTGCGGC
+
-FE7C)"&#22-)>D&/E"/*(1-6#$"*&:#9-#%%"@868H(47?1==28
@r2811
ACGTTNAAACGCNTAANATNCNGGGATTCACTGGCTGCACGCTC
+
"*"$("'&&)"!*(*'%'%&%$+)*)&*""%)!"'(%#'*&)%'
@r2812
ATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTAC
+
81+,03852?:!2@,1&>G%CCD5DF8D)/D(C943D=7)@@0-<B-;3H<8D</3)4D4/0",;@1,!"5&8:?2;F-762H$!<9,3"8:EF>8?@)D,
@r2813
CGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCNCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATANATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAANCTGTTTAAC
+
%41"FB)($9&/BBF(A#)G-4(.$9>@:C+,0GA@*DG-:$@@&9@'+C84CB/9)294;,-!;.&@'*C&"0!=4&E!@BEE7@E+9+>AHE@E3A:H&%#+F?==,597<:&&!E&!.59&-3HC'</5'G)-:GF35&<A1H>/A<)HG37%@"??1)-B=':8;)6!1!E'@?*/%((6%2:.D95)?,0CB!BC&8E
@r2814
CCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGAGGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTTGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAA
+
=<3''#*>-+'4*GF";2&.("6=#=3.(37!B+03?$*E:%/'66&<D!/9.,E*++BD2=3,)C>;7+'/#/.8'55C*6H;-HC#@0&!$;F0+14*?,H.@D56=<1B.=@$9642C8;32##7FD)8;C9$=H9A:!F?E!+8AG9-;H8&'2$!".?$707%'=?>80<B/<F51:!1+2,65
@r2815
NNGGCNTGCCAGGACAACTTCTGGTCCGGTAACGTGCTGA
+
#(''&")'%%*+#)")*%"*&)')$'(!*$%(*%$"+$#&
@r2816
CAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGNAGAAACCTCGTTGCTGGAAGCCNGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATNGAGTGGCCTGCTGTACCTGTTATGGAGTAATCGATTTGTGATATGCCNCAGAAACGTTGTATGAAATNACGTTCTGCGGTTAGNTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTNAATTGTTCATAACGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTC
+
$EG/:B71D%&?397."G?"*#9GH.BGC5H>?-"/E6!H39<)G02$A@559@1&5D9</F/=,G@37"GB6'G(?GF=D9H5>B8,>,#.-'%6-9?8>:@G&F>H6?179@;G30/B"&:A&9&,B93GG/):;BA:<8/BC!'<;=05E9'E?380&B&H1+B%*DC'E.,HF,)F6$99'D&<'A6D1::F016FFFG3!%2+*'9B1E0#+C$/@=&$BB:D:?.4.2"F><0*7/83>='D+/=0F33.$8<7D")EF/C9$9/((2<",351?@-)E)>#+961-",1D/H)19.<;#H4B>>"9E!-.@.F3E93$+"F8F0;F7)G.%8/H*=?64&?$3&:8%85DGG(;A<2*A41758A*$3#2>/H-0;+F,
@r2817
CCTGGANTGTTGTNGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTCGCCCACCTGCCTTTTAAA
+
%)$!"$$#(+$'$&$"(#%"!*!***")+%)')(+#)&"+$((!"$+()(&&*!#$"##)&*$''')!)%"*&)+($&&%('+"!*$%%!(%%!)*)%)$''(')"*'++&(%%'($!%#'!*$"*!(#&&$&&"&*)%+(')
@r2818
TCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTA
+
=45G5#B:07$C)?G!1G(!#/8>>1C"G87@7:D72ECBB5%:E7)2,(,?1";7>6+H86D
@r2819
NCGCCATGTCAAACATCCACTCTGCGGCGGTTAGCTCTTCTGCTGTCCCCCACTT
+
")"+(%#"")!)&+)&+!$'$&%"#))+*+)&$#%#"%'(%&&'"$(*$*"%%'%
@r2820
ACCCGGATGGCTTCGGCCCCCGTTTTAACACGAAGGTCGATGCGGCGACCAAATCG
+
#+%+&*!')'#&*($+%%(!#)''$(&!)!+!"((%#$+''#)$()"')#&*+""(
@r2821
GGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGG
+
H3?@&'/D$>"C$:1.5G:/+/DB&6#6.3<0E$2+GFE?%,A/CFE%AD?8&"6,2B6>E)<!/CE@*=H$5(D@<)D287+0CF!
@r2822
TNTACTATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTNAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCNGCTTTGTTCATGGCTTTGANGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACNGGCAATTTCACCTGCGCTCCGCGACAGCACGAAAGTGCAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTNGCNTTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTACGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAG
+
*"%)%#+'*#*('&$(!$"$$*#(++'#$)'!'#'$!#(+&+!+%("*"#'(%!$)*#'&$$)+&&#*""+*$!%$'#&**(%'"&"'!'"#")#&&+!))()*(#!!+"+$*$'&#''!!#*"%#+$&#+)*"(')$))$$%)"'&%&($)$$"""!#"("&()(!"&$")'!**!(#+!*(')#**(*+!(%"%$&#"!'++*!$!&&&('*+%)!$+*$)"&##)+&++)#("$'&($*"*$+&*%'("#()!!+!!%*#'#""*%#''%+*"(!')*"%&$&!"#!%+)'$+%$*&!$('%$!&!+$*(*!"##"(!&(%*$'(**'++&)%++&*%&&"$"!"$!"'!*'*!%($%%#*%(+)+#+'!(!*(%#*))$$+!#'($"()*'*"'*+'""&''**&"("&()$++&))&+&*#+)#)*"!+#!$)%)%!$#&+&$$*$'"%'&#+*))(%%($!%
@r2823
CCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGNCGCG
+
*DB>,E2:EF%?"(B3@3B77+2H$62F:3:;6#8:0G(97"44>$GF,A?7."D4>>#.!H>,D+3A/)
@r2824
NGCCAGACACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGA
+
)&HGG3!:.6/,))1E4E7"$":+!D%2,G"('BD1/(&/,:&(:&7
@r2825
TGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACNCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGNTTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTNGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCA
+
<?+0&A94+<1D0".E/<0);BG4A+63-A5"#?EA7C>)";'$!/04)E+-.!<#8?"E+*;4<2BF+G?)7G>0,;1&2C-?0"/9GEDD</F=%?E,:/+%2CB!7E&0:&7F39-)F/!7>:*43'H"'5BA5BH4)*)#;HG!!*+B*9F1%03;5$/0=.0A,':AB*,<=5@F!E38)9F=''6-A5$:"#HE.H6.4<&&0!3<%?>2@=G/3*:(D76,.#18(%&>9A!6/>52)B*#3'8@".#G4'D?(5%")72>BC///>HD/!)4,%=$#B6>,=:&9!!G!=7&457!
@r2826
GAATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACNATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGG
+
.?B4=2D0#%25E:::%@,->.!>70#)4)"9"+H*'3*;),"B7=-5*&F@::6*%%/:0-;0%<:G':+5.6@"*2D*0DG<4.0&$&AB*,4#7));5-&&;138&1736=$++C:D+%BG&E*%;#+<B.$+HB)/&4HD)4#-G@31."'/<:1293*&".%
@r2827
ACNGCGACTNACCATGTATCTCGTGCGNAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTNCCGGACAACTGCTGC
+
&*(()&+#"'&&*(#$*("'%#*'*%)*'%!+'")%'%('!+'#'#&"$%#$(&%+($!"%*!)#'(""&'$+#'*)()
@r2828
TCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCNGCGTATCNTCAACAAGCTCTGTCGCCGTCTCCCAGNCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCTG
+
<A37F;,*7%27.@))11&'?@60F--+-)@F$$%A=;DG?1&$:.(,&,66,1*=!;10$#<'++D>*140362"$H4!<&$::.%+?(E;%=77E:GB0DE:)2%8>G5),.BB*<&78;,"82F/G8-B.,F5G*<:42"6(.5:/+8!H7;'&18%E+.*BFD%B>#94BH+704*B%A1$,7.21@-@?/7$E/E
@r2829
TATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGNAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTGACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTANTTACTGAGAGCATTCAGNACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAAT
+
#<&":/!25/+)H/?8&4304:>0G=**$H7*DG)*H+"">.$=A/18+&ECE%*(>$4EB%/,(=(557'*81)'D1#(4&30C:8+AG:9/7/A1E0)!*)7&$+&*>&HA8,BD<G-<G>%,#$99'%;1.076C'@"??E:!?%@!"#!60BDB),=+A,&9F22?/*33.,9-@;"9-8<B:*E'.D)+?/0.49$'4;B5!$$"B/"H25H1D%H@!70)>9;F01'E.3&C%%6
@r2830
TCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGNGACCGGCTCACC
+
1B+F8$%G9+-*8&7,5A13G::*D7B)E2>H*-:"+*:=#:)"D.7=/;,6>$G=$55!$(%HA
@r2831
CTGTTNACAACTTCATCAGCCAGTCCGGCATCAATGGCNTCCTGACCGCTGTACACTGCATCCTCGGTA
+
0,#*E!>!::<!9,)1C84$.C48D$4(=.,/3,19G,B1%B4!B0E?<C!>A%4%1;9;D$C-H*3/8
@r2832
ACACGGAGCGCCAGTTCTTCTTTCGTNCCCGTCAGGTTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGA
+
4*F.HE"0A>"8B*3A:+,E@B:==>754':3:<*.$+)B,48;(/<4*71GD&H#94)=83*@E&/4$%BC%C"-E#.H$8"1('G2@$0FH.77E.=9)>(D?@?GD>DE-*;,39@+6.2')85%D63G>@(8D:*42F>2D6+B-*@,4C73%>F3)7&G$DE%D4=EA-"3-?FBE&7#'(.:B7D10(E564;/)5
@r2833
CCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTTCTTCCTGATATGCGAGGC
+
501@)#(4)@#-2E0#@EF5;72/8(8:$)9!@8(D*4(FE:E36?G>C7F;HE5'"+*:*D6+H$'AB94,)7@A=.?)&66A06!($8:<E6)>.7/<BC
@r2834
NTTNNACGANACAGCAAGCGTTTNAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCGCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGA
+
#%)&%""$#"++#%('&#+('&$&!&+**)("%"&$+(#'&&)*#""#%"#%&!$%!*!*!"&"*!++'))*'+%$+"*$&'%!)***#*&"#%&+(""()&)+(*#%(#)*&+&!##'(%!%(%##"'&"%("+"
@r2835
GGNAAGCTNGGNNATGTAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCCTATCTACCAGTTTTAGACGCTCTTTAATATCT
+
!)$(***&!'%%!$#"+*&)%%$$)***#!&%*%#%)$'(*!$&"$*'!#$!%&++"$(#"'!)%"%)"&%(#'!!$+%%''*(*&$*
@r2836
TGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATG
+
4FF#D-E%C;@ED"=%!A4250(?;.H1AF.+3>6H93/!43++
@r2837
NTGTCCGCTTTGGCCCGGACGGGAATNAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACC
+
#/7/2A'5B3EF;.@>F:8C>B761<H:7FAG,5F4/5%)?$-/@"#8HA?%&2A)5?27(#)*&55)@$51#-C+.0E-48)80#;%#<2<'=7.#:$>$$>";22+,%:G%*5$$!5;"3.%;/,-"G?
@r2838
ACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCNAGCTACCTG
+
+*("!")$#)!!((%'&!$)'!%"%#"!&*#**!"#*('++%"#(+'(%!%"!!*('*+!&*'
@r2839
AGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTAT
+
+DB.G#;C38#=A!1@4-+29!:.-172C89F'5-F6&F9(F+F*,-5/D$D;.(<-"8C"H$544#,%BF+50G5>>5&,@-C.0&"0"+?./*G7.8
@r2840
NNTCTGCCATAGATTATAGCTAAGGCATCTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTATGATTTAATANTAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACAT
+
"+"""&'#%&"#&&"%&&*!)$&"))!"*$$'!*+!*$&!)$+!%##%((!%%#+"'*+!*!%"!!!%!+)#$!%"&)$&(!$'($!++##(#*!!&&)$+"&!%$)!$*&'#'++**+%$$''!!&*&#!'$++"'*("'&"&*#)$%+$")+!((!$+%
@r2841
TNTCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACNCCAGCGTCTCATCTTTATGCGCCAGCA
+
##"6G-<;+7%H@'%C@<.;-0/@H<.;*2HC!9$&;HCC&-#B):0:7+&C?&G?!F.;3-?;4+";4,?3B8C3:#=>)*##:?&BA9-3D,<11:A!:H=%F%D%
@r2842
CGTGAACGTGACGGACGTAACCACCGCGTCATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCG
+
B?6/9H9=';57,%%"CHG)@C@7F='@'5A;B>,;#1$('73>/F737/B(>80(/7@,<B?H@*45@.AF?1$,
@r2843
ACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCG
+
;3>?-*B3,&?#CE0.&FH,!$>8/8:.7(:;,G@(A#@C
@r2844
TNGGTGNTGNACNCGTGNGGNATANGTTCGTCTTTGCTNTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAA
+
$!*(%!()!##"#!"*$#'&"$'!"&+*%#("(&%)+!'!"$!()+%''$%#!%+!&'+**%*&')*('&("(!+%+&*)!(%$+%%!"+$$%%!*'$%)$"#(*$%+*)$+&$&$(
@r2845
AGAATANTGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACANCACCGCC
+
H+B*2)D-EG@32D0C(&+63)D2@87,-?D+ABED'E)!(#)/&G'%>#-*
@r2846
TCCNTANNAGTAAGCGCATTGGCCCGCNTGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGG
+
&)"(!'!"+#++&$"#)*##(+*!*)(!(#($'#""(#*'+(!&#"&*$*!"$*'!%+#*()+&'&#)+"%'$$'#%"!*!))%$!)'&$(+++$$+#!'#+)'!)!&+)&*!&"&*$$"$'%$(+"*&+&"!)%!&#**#$+$#$"%('!)&$#')&*'!&##!%
@r2847
CAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAA
+
EA3"C<&C%HH3%-'6+&#+,'$/F:?B5AF>:)3@@HE<G6#C%-A?>DC/&/2&9G!05?D7=4/,C"AB'!%A1'<-)!F"EE$*$3;H,+&
@r2848
AGGTTAGAAACCNTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGA
+
33..1++&4-*93<C51H5('H";AE93:3)HH;2ABHH3E<G4873(:9;+*G3)(?01@4=B,=4++
@r2849
NCCGNGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCG
+
$=6;#CA>;>C"C"G4B5C5/&-'?99HE"#>3-FF%54*0F353.:.>9-=F!G(.D&7=(F
@r2850
TTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGGGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACC
+
!HG<$)G@<)'8-B+B+-),C)>!6,=>-A-!(9G!%(3EB-)-@5$4D6<5&+:F7E0D0F!+F$3B*C-"5'#+!'G,&&!EB6D3+"5,2<'9'C:8)=9D5-#,*'DE04G';3*H=>.!B/85
@r2851
TGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAG
+
'-F-;/+6'G1')?>A/+F2A&-D:8?C@&4HA'H.D,>07
@r2852
CTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCA
+
>&F,4E!G+5)=H6'($64#4)@B"/9"B/F41$1*5%=B$%68&FF5;%"6<%H.HD/F2/A?)"?!<#B.+9/&*+HA(&>*8'
@r2853
TGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGNCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCC
+
B(>B#/H=,#G/0@&073$/D>?=%-<**,3*G@BC!:/:F?C)=&:-"EF"$4+0G*+AD/?595/H*3=C<",?3,/+?!-@@93%4&H-A6G<+4E-E4H)+/9C3"B%!2F;,D?&B?"/<&)(1<+41GAH+H0",)*7&$72F+1@C?@;AD"<&$2#+<G38$1@H<"3$B-"(9=B0"4+<-73-6D@:3C:1::?(4?/;6%803'@F89B)6A/9E&E..&@-GC.!1
@r2854
NCGNAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACC
+
,')H&4A(/+43'F5EEE:8*27<2),=;";9<G!8(G,(3>1%"!>*E-1$E@64H7H++DEH!CA("C5G2?532CB$#:H9/D-%.)#9.@GB!"F)7&&BG>*+%43F,FB*G!G>0&1$
@r2855
AAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGNGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTACATTCNTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAANGAGCGTGTTTATCGGCTACATCGGTACTGACTCG
+
+(+&%)(*'%))%#%')(%#(!(&'%'$*%$%%'*&'&#()+'++)'&&&((%"'(+*&&)*)#*"&"+''+$'$*%#')"&(%(%++)"'(*#*$)!&$#+##)+")$&*"$&()('(')%"'!'&(&+"+"!$"*'#"(&&'&&'*+&(%!$+)$)+)!$$(!#'&#'")&+"&+*#%)++*+*%!#('(&&#+!%+')')*%+&'"+'!#!!"'+()+#"&(%(&!")!%!#$$&)+$(+)
@r2856
CTTCAGTTCAAAACCGCTCCCCTGAATGGNATACGGCTGATCCTGTCGCCCCT
+
(0'A-!%8BD+E$,F23$'';>0B#+*::#=2:(*<',7F@31=,:B=/8*6(
@r2857
CAGCAAATACCGAAATATTTGGGTAGTTGTCGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATC
+
DH'5<-$#%DE<<0=9B#EC,&=E)27&%5,A@"A&,B?46A)D;@>A4=B,>(>F%:&F2D2G$)&+G+8B=)<(,GDD.C9=#3509B@B83.=:":)*@<'01GC1"?D85>8)'&A#6.2F=-9/?G2"5%5*"<9+?H1<.2E3&;*;9@#$5G/#'='++
@r2858
ATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCT
+
=3=?<G0E4008,EF@=F=,4C+778#7&$9?EH'7;#,+,+D2AE==;;949:8/9*2<5CF",?4=:"D'H6;.36G2"*71?D!"%F3)BF++<>(D
@r2859
CNATTTNCAAATACCGGNACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCNGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTA
+
*'+!$('!)$&+'+&'(&!)*!#$$&('#($*+$!&')%)!!*+&!($*!"+($)!(%+$)'+%#"!###+)%(%+'&*"('+#'++"()%+''+&'$"+%'"*"("'"#
@r2860
NGNNNCNANNCATGANANNNNANATCAGCGGANGGCNNNN
+
#$#!$$$$#!#"!$#"$!!"#$""##"$#$"$$!!##!"!
@r2861
CTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGC
+
8@A(;5&!)B%A!<<632A>H-#,@'4-,;/(:4G0$91;->"G$3>.0"C5A2HHC61<1A1;4+BC&>4<#@+,)3E+"A5',0C/:?75>@>#&>AD-
@r2862
AGATTTCTCTGGCGATTGAAGGGCTAAATCCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATCCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTNTTCATAAATTGCTTTA
+
A;HC1:<0#H?-F<*A"=,-$)+8)D>G(B<<=)*D"HC40))"#8C*@93#C*4G7:+#@)<D8+H@D7A.CA&E@8<5%++E>#1=,9!F"A;"<+."F$(HG5*<#;@3<H.4F@/9;(?EDC=*#5.A@!=(+2,=6.<;6(0<=/.*?6#0$>G4=..1*-1#.#4E5!H6D>%99DG6'5=D9#<F=,E%0'.F
@r2863
ATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAG
+
E783E2D&G"-G+)5=/CCA"%<?<";-@#"?&<:AA0F-3*5C
@r2864
AATATATTCCGCCTCATACCGGGCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTNT
+
""#B#6-;&F?)A(G3A5!$>(F,#1'(9.?!62:'<18<@FC&&/<;<C29FHH#8:39EB8;2E5.=',/&'
@r2865
GCNTACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTANGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAAC
+
&(&")($($+)%#"!(#$""$(&%''(*%#)(*%)!+$'"#&""()!#+"$$$*!!+%"&$+%*!%#$$$*#"+!+"!!'(%'"&&&+*$'&'#+("&'(+$*(!#%%(+#'++#)"(')!#''"''#!"!#+&'$)&%)"$%"&*$)'"&%((*&'#"#'*&'')#'"+*&(#$)#%)')!%$!)#$'($)!+"&(+*+%)'*!+'*)#%)"("&(+
@r2866
CTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATG
+
B=0(,0&G%!(4(D1*C(;5B;"8!(!#H,8'4EBH?3.1FE>70))=-@:!4%E83D<@=#+>*(HDCG>79$0
@r2867
GGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGAAGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAG
+
B"<HE6?F8"4EF9EG=E;$9*5/7G"1H':>F.(+&83.-A#37!/!C*!=C/$21>$2@"+E/%.*21E!<6-*:6&2%$=,<F;.AG4);#F:#"FC5:/-G9"5)
@r2868
NATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGANCATATACATCAATTAAAAGTGATGA
+
".4>$;/).4,$FG,G3$#B9G6G9((FB-+>:%/B6=B0&@G>#8A"0!"6$;5G!2=1&<68-0GH36:=6A6#5C<!39;:'8>1>"/7D,03#!.D(82'?DH&4337<D<!;7+3=5$AE'
@r2869
CACNGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGT
+
G;FB(%"3>#%GF4':E#"."AC:1&/;/1'DH8@<!4$2?C3E9'=H,F346($F"56>8C&
@r2870
CNTGNNGGANCTGTGTCGNGANAATCCGCTGGCGCTGAATNACGTCATGTCAGAACAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCNGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGA
+
($*&"#$%(*%()'!)$'('&$*+""'"()"*)'*)!+#)$*&'+'')*)#)&"')!*&+&(%&**#)"+*)"#(%'$*!*%'')+("#!*("+&#((+(*%*+%!)'(&)+'&'&%++((##)#("+*)%!*&#
@r2871
CTTNCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGC
+
#$%&*CF'3G3-!04(+/9@?$"-B'A#H.;B54D%58'-=1B'8%H+)739!.%2#*:@G30%E+>0;F;>DG*CG/F-'3H1->>)1)!B18-80-:44C)'!"-</E5D9-8&0(&<(6>B#?
@r2872
AATTTTTATGGTCCGGGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGNGTGTCCGTGTGAACCAATA
+
+$+"*#&&+$)!(%$#("**"$!'%+*($!*!!+&!#%+++&)''"(*%&#)'$!)*"##'(&(#"&!"$!*"!$&*!!&+!$*$(##"!*(*$#%*&&")'%$'($)'*&+""'&##'*$!)(')&+!((!)((+**"*+
@r2873
NNCGNNGNGGGNGNNNGTNCTNNANCGCTNNCAGNGGNGNCTGCGNGACANNTNGNANNNNNGNNANNC
+
!##$!!""#"!"#"$"$"!###!#"$!!!"$##!$$"!""#$$$!$$##"#"!"#!!#$!#!""$""!#
@r2874
CATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGG
+
/<2%@-D+//?,!9&11D)#H%&)8%.$"/;*&F(B>78H-#HD='3F+#*@>=6
@r2875
ACATNAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGNATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACNTCATCTA
+
*#**!+"(#&)()$&"+%)'#)(#$')(%!*+"+%+*"(+))%)+&"%#&%'!%$&#+&&+**$(+!#*(!)&*"%$%"**+!"()+"*$("'("(##**)+")(+)+$!)#%*"
@r2876
GGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAG
+
8$C=2'.$&19*/*8AG-$1!(9&A327(0G'!;B,71$"
@r2877
CCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGNCTTTGAGT
+
-@8;"&:!1&.==0/88+*!<B3$CCD!89"9,#,>A'D*1?G%;A+7:%.2=A+1F85.0&+F9.%,:::=08C59</750A@%7
@r2878
GAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCC
+
<357/"6@.AG<(;!GD<7"97@C:#-!817.-%$F7)!(F-$34,1>@A+=.A(2G1C8=A2E7C#3G8'ED6H834'1&;#A75!"9B>#C8=04B,3<??,G%C2?9H(A0B-$7:,(>>CF=)4G97D0.>D$%(891:,*E@=>=$G/9/#17
@r2879
TAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGT
+
33/&93HB73>G(E?G365#A'8!'06?&&0E*$!?;16('1.-
@r2880
NGCCAATGACCTGCCTATGAATTGGTTAGCAAGNTACTACCGGATNTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCCTTCACTTCCGATAAGCGNCGTAATTNTCTATCTTTCATCATATTCTAGATCCCTCTGAAAA
+
$0FA<15>.*(3(3*"G:&(!"27;2/&56%,,**6&C:$=B89:,%F%@@?$:C>C?89E"$0-22>#783A,"A/)1B,+7>C&5%606H@8&%-.3G6"A?AE13!7)>?C/E2(C;"@7<-)";4E31*B6A.*/0F4*
@r2881
NTTAGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTA
+
+D(3@6C.+0F;372<*D0B=#'(#2;-<F)%'<::'+66*:;&32+(8E9FG2?D-(@*E/+@!+%%4?7B!*@2(86*$*=G+7-2F0?'
@r2882
CGTGATGAAATTCAGACACAGATGCGTGATGGTGGCNTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGNTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCNTTGGTGATGGCTA
+
>GB<A6>/=4-A,EE,@G+%,:@;<AD8049:A'<>">%"2"%AE6))<9-'DE04=6*@?--.=)?;H")F%-!=E<?()$H@<D$C<)!:85:0,):#/?=6957@89BBFFG?)3A6FH>35B$@$?F!>+=67@'A,'
@r2883
TACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGANGCCGGAAGGGGN
+
12!''1'5(!/5,?-?'39<),8B24"):BD<?):@)8?9G/$,@?=)E)F
@r2884
CNACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACNCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAA
+
%"D@><?52,37#:)2HE@AA@/5.B.@3,%@DA..7:/40HHDB7<)1%)G-E29::=>*&0CD'.=?&65:1'+@)?6,*@9
@r2885
GTCTNCAGGTGCTATCTGCGCCCATATCGTCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTG
+
!*$(%**!%+$$&%((#$!*(*#+#)*!)'*"&#%$$$""+*#$$&*#+(%#'*%'((&#%)"&#"$*'$')("))
@r2886
ACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACNGTT
+
2!5.-&76->@?9@C*4&D5.D1:<#D5'20".B8;)64'&0/(-+B>('0:=>.F3+A;4)H&*(1D
@r2887
TNNNCCNCGNNCNAANTACNNCNACGNCGGNCNCNCAGCNNCANCNTGNANGNTTTTNAGNNANNNNNCCGNTTNNAGCNTTTCGGNTCGNNTTNGTNCNTGNACGCAACCNCTNTGGCNNTGANCNCGNNCNNNC
+
!"""$$$##$!#"$#!"##"""!$$$##$$$"$"!$#$#"""""#""$!"!$$##$""$$!$!#""!$$#$!##$$##""#"#"$##$$!!!"!###$"$$#""!$##!#"###$$"###""!#!""!!#!!#"""
@r2888
CATAACCAATTGTATTTATNGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAAC
+
6E!*,H3D5,C$3EE;#;<!?#1$:''C/32(@8"1>C?1;3%9,2):'A:.4)9,8>=&-2"E#?#>A#0(-;3H281@%;&!EF&-A&:$*+=>+$166%8C1A70F@E*EEH>
@r2889
ATNCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGCCCANCTCCTGCTGGCGGATGACGCAGGCACTATNCTCGCAGAGATAAAACACGCTGGAGGGNTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGNCGCCANATTTAAGATACNGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTNTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATAC
+
5.7HD(>)C:%16.)(97!@C!F8':";!()#+>%HE+6(6GF5.3(;&#9$C+EAF$A50951@<,094D(";3<&:E$,9*;5C25%)F2)#0971%=5F>##DG5*H>G;*)$>?*5&18H%!D&/G)/DE!$A,0?'9=3FAB=2C,<@*8"E.C;)?A"0EB?/D+6@$-E>48A0D>--#DAH&07*>#%&BA1H&?9<8$<0,*<;-7.@0)-C==?5G-/:84?9'+A7&<7$*>2!/'H&17)3DC0?>3,=?&$."=?!>,:.,&>?)&(%ED(60<,,-BE7%:8*.A=$71>0$**D#>/G?58;9:
@r2890
NGGTTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGG
+
'"(+$+'+''&$%$)*+&"&")*'$*#%$$'"#+$'&'*+*)%&)$*$!%(!'"(#+&&+''$)%+$*$'!!'$)+)))%+$$"""(+%$"#!%&#$"%$%%+$*#"$*&*"#$)"()!*)$%'%+(**
@r2891
TACTATGTTAATCTCAGTCTATGTCGGTGACAAATTAAGCGNTGG
+
+A<?-3B;@">EH1D92(:&C22?.!&1.H.B?,)6A-8<6%+36
@r2892
CTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATC
+
2>F&'"&4(3%45?&)A=F285G!A?*7@(9'%6C5=$ED"#!!81-H0&7;)(
@r2893
GNTNTCTCGCTGTAGGGGTACACGAGAACNACCGAGCCTGATGTGGTTAAAA
+
%&(#%%+%!*'*&'(%+&++("$%'+*(!*#'+$+))+'"*!)'!""(%*%!
@r2894
CCTTCCCGAGTAAGAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAAT
+
'4?A"6+D1B:E60=&G!*;-1C>16+./B7D4C26:,*'*"E-#/6%8G?GEG5/3@>'*!F04#$8/,D:)97<E((+':2?DB5;;;9"()32/6A=H-!FE("F9:-#"!E7(3F9@5+37))2D4<EH,'4!,D/C&-G)*E=E*9;*7<;CD&/-$B@/F$C)>!@-!?3#6E>>B!<!#(F--<#2($@6849F:*%35A>((',3H??<
@r2895
TGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCNATG
+
*-1;4*E=)B.5/76G/BB>)*#==<!%"/+>-87=@,G9F#%F0&%A6"B%#=):&E5E$B=(6'8%#4G=D-;>2#!1?3B;4@C333./D23+%8<"?7?>.'4"8%61&=89>231?A841071:<)/<8
@r2896
GCTGTCGCCGGTATTGTTNGGGTTGCTGATGCGCTTCGGGCTCACCANCCNGAACTGTGTCCGGA
+
0A%'66=A.@&C</E0,8@!D#"B(6%1B"%9>09FDA..;F"=?0)"(4-57&*>3543565*#
@r2897
TCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGTATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAATACTGTACTNTAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGNGACATTGNAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCNGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGG
+
6;3!5+2DED3D9:D#''>FB!54A?D#FCC!+='@;':/<;(2@HDC/5*%A!0&#.<H>&0,"H877>":",@<?*C2?E7:@7':4B<@-=>!-CF7@#;H+/5+<!2B2(,)#G<4>%=2D<G&23B1-<080;;16?*$:D&39E/"GAF?94D870)+<EG;>)A>1!4D?&,9;@4()2A@D/+7;EA.)>)87%,(E66.4019C:'<F+8.;''5$169*#);+C)8?:@??:+E<3-B8@?AH9,G#07D77AB""G2@7=*$1A9$D-%8(B"F9,#@=0(B="-<8F+@F214(@0;@;!)/#,'(H66+1)(7?B"<D,H'"H@>";G&4D==;:B0?F&G:3B;.%AD99.(:1:=%6++DH7BD'EE;"A,D':<:>4""8.D.2H*>&9!"6F
@r2898
CCNTTCCTTTGATGACGATGTTGAGTNTCAGNACCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACNCGCAACGCTGGCTGGGAAGCTGGNTGAACGTGTCGTCATGGATTCTGTCGACCCACAGG
+
$%!"'&#(+$&+#!*'!*&")')$+))($!"&%$(%()"))%&+*(+%%%!'"&%+%%*!$!$'")!+*)$'*'#*+'&#*+#$*%&!&%##+*!%'#%"$#+$%"!((+!%&!%%#!++!(&$*!!$'%&'*&"*#*&''!*%(#('#!"##+%!%%(#$&++()*"+$+""(#!#!"')!*'($)
@r2899
TTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTT
+
%HF<!&1#;D-<-@A7F)G)-H$=.?#&.546#?#GAA4C'1.(6)21A'&,5'#&1EA9+@7E5%&:7#+@!E)C/./@$.@?$<$/0F7)03"G48=)#,CD-$AC+38:@'D@3+(E:;5D=EH-**EC578:<!8CB
@r2900
GACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTA
+
<0)047D<>+34>%8A3.1A@7!;.@261:"%;$HD,/GB3.*:5
@r2901
GAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATCTGACCAGCCAACGTCCGATATCACGAAGGA
+
CE5029FG;9%-)A*#A?(%,.B:<F-:7:'?&#)?H@?G*%:)0$G='>&::8<))0?A<$&E,<<<5!1C$3)*403=!#B,A(A,.8F?,9@-#</'<41?;?0(0?13%6<HBFB471$3:!:C&H;.4'?:/':$&1>3C#GF!%!;//*,$5289#=+G1&0
@r2902
ATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACANGTCCCATGTCGGNAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTGCAGCTTTTGTGAAAGGGATGCGGC
+
C!#*146B,'H)1>.E*:G;H?<@&=>2?5223*H6A=8F&>,!+4@>@.5D&#.*+'9%C%*D4%D),5)9>1H&!?+H3+(?+>*/"=?$F)6;;B3AC1?B4H'.(5?C2$/D/B?)C;A@(94E"4C)4>H8*4+&)D<5B',27796DG/?F4(>-HD1"/=0+1,&!$%)<5CDA.")"4;6F/A&57$%<C4@%8)0$6=CG;7B2>:E686?#3#&7GF$EFF5*!-5*3G*2::B/:
@r2903
TGATATTGATTCAGAGGTATAAAACGAATGCGTACTGCACTCGCAACGCTGGCTNGGAAGCTGGCTGAACNTGTCGGCATGGATTCTGTCGACCCA
+
*+"*$+%$&'#%"%$())"+%(!)')!('!*)*")&!"#&'!%++)(%%$"+()'*"!(!%+#(#%%!&$%+**$+")#&)))#)+("!%!%)"%%
@r2904
CTGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACANGTGGTGAACTGATGCAGGATATCCGGCAGGAAACA
+
'"&.>5"-%?/53#-7<BH-"*3--E*CBA7A@H&D!,5=B15;;,=BF3E!H3+0?C19AH43=-2!@3DC!-4>9?#<
@r2905
GCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGC
+
H((;9H6!2//D7!!A-9"F3</(*6)&B#B1F367"%!,>1H,7F3G#4D-G%7('C?(/&G7@+BF9<85E(:1G<90
@r2906
CNCTNGTNGGNGGGNNNCANNGNTNTTNTNNTNGGTANGNGTNCNANTCCCNGNGNGTTTATTNAGCTACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATT
+
()"'"$$!$#)%))%&$%!#'*%!#)%'(&()!()%%*##%!%)#$"&*%(#($&!(%+##&$(+*"%%'+*"'$((%+"$!*'&++&*"!$&*"#'"!)!*#$#!)(#)#((("$#"!"!!%%'%(&!
@r2907
AGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCNGCTGGCTGCACTTGGCGACAAGGTTACGTATAAGGAGCGCCTGAACGCACTGGNGCA
+
58,?!&3/.E9/6#B+0<797=BE237FC7F'9;#@=(G>83.G(A'5.+(E"*$A":-'G5<(=C&D0$@,<53>EBC@3+E,:?!#*A"E*(+#)=):/5"!7FC=0
@r2908
TGTCGTTGGCGAAAAGTCATTAGTTTTTTTCGATGAACCAGAG
+
%1%%#C'752C-F8F-G1?"AF;:&,2')H?G>$1B0E8#31/
@r2909
ANANANTNNANNGCCANNNNNCNNNCTGANNNGNANGNCNGNAANNNNGGTCNGTGGTNNCNNTTGCANNNNCCGANTATGANTNNNNNNAGTNNNNGNTCNTANNNN
+
$#$!"!$!##!$"""#$$!#!$"#####$!"!#""!"!$#$##$$!$!$"$!##"#"$$"#$!$$$"!$#$!##!$$#"""$$$!#!""!$"""$!"!"!#$$#!!"$
@r2910
CTTACTGTCTTTGATGNGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAA
+
4=1#+2*;'!+DD:/038+>AFF"?6A@%?)),(!.D'3B098DH/?<BB*D0%'+7:@=*#>":<ECCC*
@r2911
CCNGGTCGAGCGTCAGCGTCCGGTTCTGGCTGTTCACCGCCAGCA
+
#"$&*(+++')"!#(%"&($$(*#+''%#()%*")(")($!'%(!
@r2912
CTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATAC
+
HGH@7$).!3B'=H::<+,"AF:*+-.(C$D.<<8%%4(E?=8+5F234F&E1+&>-H/06=,;%<?.&C/9*,'59'&"-<?19C>:,?!:!7#HC3:DG62G#9!C17?G4,@:$'D%("$E%H)+(84C50FC59;FA5/C5'GAC/9(<<(F@42F#,D0B0./=C(:'&F%C;FD10<<*@H+?8"5:2,'=,D
@r2913
GNACCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTC
+
8%!9C2D82:5".2-A-?-G$18B;22+(*&5':.'HDD/E.D!@3*F*,8F94.8>./7<0H5"=7+C9&H&AF;1GH;&$<&7>43:9%1@'E03;EE(%EHF65C;%5642D!+;%&9:G;B6+@H4/*1:)0?(4*G7@#).75HF)'6*@";A"AG('7,
@r2914
ATCTGCACCCAGGTNGTGAACGGGCTGTACGCTGTCCAGATGTG
+
D',;-A50A'D$9'@DH>DC#(>FE@<374>+DC;)1H'"5-0*
@r2915
GCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCNGGCATGTCAACAATACGGGAGAACACCTGTACCG
+
3#=@#-D'3DB4::=7:+D/7&>'A!)393>D;#BH61"F%61+1E-)CH=;/<9%>G7D:0B#,3!('63/HE7<;E$=#CH%&"30B(+0"'5,*/-A%'8,<C/BH*A.5>D
@r2916
ACGTGCGTCCTCAAGCTGCTTTTGTGTTAATGGTTTCTTTTTTGTGCTC
+
EA'E(&9#3&.=!F,$!C*-6&6$!41:H'G1F$"="):(3(#&,'&6(
@r2917
GTGCAAGTCTGACTAACTTTTTTATACCNATGTTTAACTTACTTTCNTTTGTAATAAACTCAATGTCATTTTCTTGCAATGTAAGATGAAATAAG
+
G8?F'2E"$H$D,*@&<4<(D0=C%-%4-D)D#$%>:;02208.!9F:0=F&6''+<+5"!3'G&=G+/A)4:*C*10"-A-F&5.2+(GE,5&'
@r2918
TGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAAC
+
1'92(F!@1$;/+!9!F*=!;/#+9,*<#4B.,(&/*#57?
@r2919
CCGCTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCA
+
6>.6@AGE/3F-*>22E'+2B=#1!1@BB90-"DC7A3$3F(#/E5@55G'CG9B6-?$&%20FH&1+<1@#'A@
@r2920
GGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGT
+
511,);&'A*9124/(!:.B97A&ED6+&D=<D&3!D%>G
@r2921
GCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGC
+
5H7H7;!2F<#:@:>8*<>F2&D'1')D=EE(3H*%/!G"$-C3:)$$3/%-3?#%)&=94*
@r2922
TNNCCCGGATGTGGCGGACATGACGNAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAATCCGGTATGGCTGAACCGGTA
+
&#!:FH7CE,9692(&.*%-0E?!8#1<H&C0+#=;&(GA1G#'1(.2(3=4$&,(FC#.%4&)D+3!3(<.=*5'(B4<D9&D"=GF*5/*&4<
@r2923
GTCCAACCCAGATAACGATCATATACATGGTTCTCTCNAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGG
+
0:>)448:;"HF@,$(#%!?7?-4!00.B*!?B)B6F>26H"83?E6'D=94<(A6=C.E('=3>!!>%#::B,!#<1$1/'%5!:/#B@81F2;!+!A*448E'48C(<
@r2924
GTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCA
+
2G$,49:!"6B,3C0C>7F>84/C*58&C5%/9//21/G66'!8659&E9.5@F$&$=91299
@r2925
TCGGTTATCTTGCCTTTGAAANAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCG
+
,8!2)'5@@$<4*3:F.>?5;$H"A;7+26ED=%B*>0".,#2:FAE1?A&CF,>$EB'#C,FGH*?A!8%F8<&"G3#
@r2926
ATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGA
+
(82B:B?8C,&+=$B,$?B+6"DC@>*1=?$(@3$E02#9.+?9
@r2927
GCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAA
+
.5%55>#6&3);(E($"E$'/;7$/#)(>8050/?,2,7>$>
@r2928
GNAATATCAGAATNACANCTACNCANNNNTAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCNACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGCTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCNCAGGCACTGCGTGANGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCGTGA
+
*%'$')!"'%&)')$%("(%#$&("!#!"'&++'*##"**!"%#+**%)"*%++((()*"&%(#%!'%%+'#$!$!!#$)&#*&%#!%#('*&&$&")&%(''$#*"&&++)'')%#"''*%&%(##$(+$*&!%+&%)(&('++'*$"$+')"#%'%)"!*%%&"'+(*)$+#$)'#)%#)"#"*%!')#(!$$*""$*''%')))%(#!&("($$&!#)*++("#&!*(%$+!"%(+%$!#')*+(&*#&+#&'(&)(&#"#)('#$!($&(+%$!
@r2929
GCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGCCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATT
+
60D>0B%1A2##0,/D%?%+$(E5!F6(1F/G%:(G7)7/;C=G1*'@@$90'F(21'86F;5'D&G.DF/C>(10"G)48D27:15;4-$1A?!GB/>.2%D>=@)@A;BD7%7?;%88&7%:C"&.)'%H;.$%B8B
@r2930
TGNGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAA
+
'$++&!$#&%+#)*!()&&#"$%%)&"!"**##!#&#%&!$'#+$!!#!+"*%*#!*+'")#(%+#$#%!#')#*#'$#"!)'#%)"$!($'%$"(($*(+%%('*!+**$#&(!)*$*(!&+'!'!'*(+(+!*$%
@r2931
CTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACTTTTTCATGGANACAGGTT
+
>?++$71#H(;$C4"D,&5C76.(";5DH2=710CB81+179=.D?=:E4D'CC+760B96'#'<(
@r2932
GNTTTAANAGCTCCGCAAACTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCC
+
()%!()&#$'+&&'&+'%!#*%!$%$%'"$(+&#%!$)%+)'""*##%'"&+&#!&#))+"&*!$(++)(+*
@r2933
TTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCANCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTT
+
CD6)F".6$+.D$5<*B'($6(!;0>%++(*A."E)7*C%G)@E18'G5(.=$3(B65D#D*"<&'6@8*''F@&"9$=)C"#='G<C;.F@*4&9*+"G9C*D".===.$C;.C"6(',<G
@r2934
NACTGACTGTGTCATGGGATTTACTGCGAAAATTTGNTAANGGAAAGGAAGCCGCNAANGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTA
+
*&$+!(()!$%'%$%'!'(#*"+'#%%%%#%)('!')&$+*!#!+*++%&+!"!#!$+''"'#%%"%*)!&+%#%$)*('##'+(+&"'$*%+##*)**#)#'%$%$$*&*
@r2935
ACTTCACCANATTCACCTCACGGATGTAGTCGCTGCCCATCGCATNCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATANTA
+
(=D=>4-)>63H,A?>)%>*6%E<;1B-9.&(&+5":6,F60#?;77<:2.6=))/GH%299>;G6.<42G>0.G+4.-#,/HB;BC0CDAEA":0#9?:?%F(DC8<&0(E*;&))?
@r2936
CATGCTAGATNCTGATATGTTTTAGNGGTGATNAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATNATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGNTATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTG
+
:4+%-.,+'7E+0GB3:3F#=H%)C:F@%$;93F0C@AE#)66GB9-C;/BF8277-.D%<#16%4#8/"%>6!(114,%C;"F(3@,3B-16HE+5.A8%19<?-"$$&,.8@5E#8A"C?1@=(%0:#)&"7,$;E6D<"A,@&,!4'C%7&DC&?-180+*,3.E<%'G/G5$#%(>(/E&)*%#F,D#8813BBG@FB;#8GF#:9$+E)>G3$8F*=)<&'4-A<#1F,01'/2"H)78E2.#G?,E-$<A&@DA/B2C(;&#;.<E-@"H#."/:)%"8/
@r2937
GTCGCTCNTCACCGGATAAATCCGGGACTCCATCCACGCATTCAGCTCTGAATCCGGCACCTGAGCAGGCAGGA
+
!$%%+#*&!(+)!"#)(")))&"%#!(#()))*#%+*&++$#'*)*)#'+(!##*+*#(&)&)'$)*"'*!(&#
@r2938
GCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCCCCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTATTCCGTCACCCAGCCACCGT
+
-7;C202+H>%;;*$6<AE68F9DH.>?46"@G=DFG<0#/A%B,(0A@0DGG6,H=8;@E?$+:D*8,>@9,7*8G:C!''6,'5A&>3;;A9-1*>'C<BC/@)!:A')E?79<
@r2939
CGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTATCCGGCTGAGTCATCGCCCAANCTGGCGCNATCTGGGCATCGGGGA
+
0*F?:%(#B=8D&3%;><#&E1?$D%((+F-DEE!";:63(8/.C.&-$*6F;22B9A*:44:B@76$B+#6>D=?./$=*4=%-F#
@r2940
TCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTNCATGGGAACGTCAGCCACCATTAC
+
C70.(F!EAE4,HC1)A12C>;510>:9;,**1*:8,.4'1G020GB)6-+<<:*@>=(037$'C7+
@r2941
ACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTG
+
/F!91<+<E-HE+2G":HA2B'$+@A864>A(<$GA8@.G$&5D)&C"B680H"<!=),.GA#/H+;."61?:HG5G5.C+@DG$'+C/C@+'H$AD%/BF&G'BA<87G;G
@r2942
AGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATGTGTCNCTTCAAGTAAAAACNCCTCACGAGTTAAAACACCTAAGTTCTC
+
52.A%?=H&+D(04(&D;(#H@#*G5#@G$(*H94GF#&=>+4$8=)8!E3#F2/AF?#$2?*A6##ABE%9:3$DH!27'%?/B/1=4$*FCF19(<?
@r2943
GNNAAGNCCTGGGCGCCGGGANTNNCNACNTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGG
+
)'$&(#(*"$'($'''#&()(#*%'#)&(#+(&#$$&&*($$'(&"&)""'+'#&'#&'$"#%!!%*+)("+&+$+$+!&'%'!$)$'!&!$$&$&)&&&#*
@r2944
CNTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCANCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTNTTCACGATCATCCCAGTAACGCGCCCGCGCTTCAT
+
&+"$&&%#)"'+#*)'$%+&!'*!'#+$!#)*%)(+*#$(!*()#"&+()&+#!!&')'))$)('!#(!+$!!)*((*&#"#*"%!!&#+"'%$(#&)''(#$)("()''&+#"))*"$!$#"&"!
@r2945
TAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTNCTTGGGTCCCTGTAGCAGTAATATCCAATGTTTCT
+
#E/D7%3,G><61=(+.$63;;+?"?/4,#E!A%6.,<4;A(&H:D:9(CB8%'3'?2@4'(D+,ED0&#<-,65B:?F<AH0%51/%=A*
@r2946
AGCATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAA
+
#(3$G8&1=#:>*H0HA,41+*$657$)99:.)/4H,G<4/85
@r2947
GCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACT
+
%;>*&7A<FBH-.C(&7#,)!0H=BGF/3.%:@/49.;'?$'+A71=#/"@0/9;;#,>('
@r2948
CCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTNAACAACCTCGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGG
+
67'D(?:A8@91B#'5>=F8<(E?%=,:727H7'4>#338D!8'@<5=C3/$1G(H=4)@%.$(*>C*(2/&B*("988E$/*,%F;&,A@:4F/'>))/G115>B7A<-$8'8<!0<!884E'*-7<*G?>;123)CB7:(H?7<*EB=$C59*EHE#E19=2+H'A3:9*4';#"!94D%B!'#'C5-9*>-CD(628:(1+4<D4)<GA*<70.1*GF77&!/H%>("!'76B#=B/5)*;>CB',;%*%92*.GAF-D7)..9)67DA(.BF>"H&>
@r2949
TTGCGCCGCCTCCTCCAGTACTGCGAAGTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCNTCNGGAGTTCTG
+
6)CDCH/1)5%<59-D,H@F>$=C77E<.FEDC5@C$,B?(C-F253E*GE12D)+<38B?#.!;1)7DG?2"+*#!0,/8HG-FD*-H3;488!@5$-#=0#@5E>'3?%A,
@r2950
GCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTC
+
@'=+74-+7;(/.BFC7ABA33F&*-;%'615?-/)7./+@$6/:,
@r2951
TTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAA
+
$3;%,G4&4"(1?@F76$?!)+(@(G?&,--0@#08558$2E5%F.4#7,-29A/'):H6=9
@r2952
NGGGTATACGGGAAAACGTAAAACCTNCGTAAACACCACGCTCGGTGA
+
%1@%C+'2>)<"!(?"4.&-96GA5$=+,-$".'5D2".+B313A1@H
@r2953
GTATATTTCTCCAGCGGCGTCTGCAGCCGTTNGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCAT
+
+(&&*%'#'%!")$#'$'&"(&*+&&+()##)*+#&##!%#)!$*"%%*'+'))'!$%+()#'"(+!*&&**)(%#+%*"'*+)((&(&++"$$&"&"!$
@r2954
TAACTGGCATCGNTGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAANGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGA
+
*$"&*$'!$')&+((+"+!+(&!$)++*)"))%'$%%("*)#$(%)%&()'*+&%)"!*#(*#(!*%)#$$)*)!#(%""+&$"'(&(!*#'')(++""*'**+'*)
@r2955
TGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGNCAGGCGGCAGGGCTGACGTTTAACCCGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGC
+
?+(!HF7!D.+F?'/7-HG>(&H055.*>6;A=6,=C0>"#@;>2FD2H85B6@07D3!A$#4A@<*195C@C6%,3@;8/3>88:8*:"/$$7(;+!%(;3G>;%.*C52$5F#7%<54;+DG(%/6A?,H$CE2!%,/3>!$>0>43*497B6EA'8?+>4-?4!#&'7F,$@,$.8*C
@r2956
TCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACT
+
D4/4<>&ADA,@,0BE<3/>#E/F6FC$'&++/6+89;;#%
@r2957
TCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCANTTCTCTGGCATTTTTGTCGCGCT
+
>#B:<1+DF3!0GD5/7=,D<"%5H,G8AF,6G)*<0?''32A@*$A,F=8F4+0=!8:.-6C+)-1$(?"HCG/G$AE8-".8G+0+
@r2958
CGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGA
+
/3+=7)99$G2%@CC+,(D'>C>5:!7!-D,BC=)50/D.44>;4(C0..0*F/$C*4H="3,B
@r2959
TGTGTGCATCGTTTTAAGGATTCCCGGACACTCCCNCAGAGAAGTTCACCGTCAGGGCTGTGGNCATAGTTAATCCG
+
%=;BF3';;78=G#!(?+#";-D2@640.(<E.7$?78$04,&=(1C$D5-G84/GBF93=.9-+'C#">5'=.345
@r2960
CGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCG
+
HB7CE.6'7,=D*=>-/A/.?$2>G/''3.)$D=5,@HDH-"B=A%";:$#;2
@r2961
GAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGNCAGTAATTGCCGCGTTC
+
'AH%$.!-@5)H9&44F-"D+)#$93E8$C0D!*9D,#B66:2'0*=%D<:./H41&2E1,DBF0+<%=9%1>'1;=?01%$<"'C0AH3;*4?63,/8782&-
@r2962
CGGTTTTTTTTCCTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGAT
+
<9#"0F<GF&F131!*$@,.)%CHAE(9%(A--;D3>=/6'"H+;+C;8@HG7
@r2963
NGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACAC
+
"%>23D$E<C34"B3?A'4H"&**;@!;&-0(-,D.F,6A70CB=";/B%F:1E:0<DGCE43,3@+73=2=+FCH28)A.1$)$=!%E#.8C'H'$>C)60G"A$0,#G7&<G<9&E&
@r2964
TATACCCACGGTCATATCCTATNATATGGTTTTTGTTTTTTTGAATAANAAATGTTACT
+
$&'#*#%)!$&*'+*()&+!$%()'%&((!$!%(#+%")"'("#$*#*"((!)%#(*+&
@r2965
GATTTTTTAATGCAGACTATGCAGTTACCGAGATGTTCCGGTATTTGNAAATCGAATNGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGC
+
B'.<?G3H@0((9C03."=2!.H"GHHE4)='13*C>?>BB8;<*832'F7EF07?D$C,(?>,*=%E"01BHB:CH,:5A)($?(1/C5EE>!A:E=155E@&GB6B14<4B(87-E6"E#/%;C?"'<C)428:=$"(&<@8(5-#-1%%E(!1GH7)809.6:,5<;2:%/?**H(:).,.A-9@3@>1C7,
@r2966
TATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTNGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTNGAACAGGTGGTGAACNGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCNTGGTGCTCTGGGAAATCGACCTGACAGA
+
5007/#',9(FCC!'9D(B5,?65//%8FD5H@,1=7.60!@A@,A&(/)%.#C8+=5H8DA/=+B686+#"1'(!+B0D.695BD85H7.AHE?C33B);890*"/2!GH50C0,9C665<3E*/AF"96.+'%-/2?A(*"-AG294&DB-:B1%1$8*,FA0:F2@81+3&"?$697&)3"=DD6/*
@r2967
GTCTGTTCNTCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCANCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTC
+
G@/%68#'5@,F4:D9@&DH./&086G+*(1#+)A/$H&.0GA>7H3C)10/->4#.D"#)E(?#8;HF>02,++FH.D2FE87F@@/6,294DA-!%,,5>0A%C19AC%0D/9@9<@:G;H@,5*03:E;D9+!@9,,1A=&3A*!2;'E1E8;)*>>50:?37?H;)<8A'2!A&;(+4#!3($%&E<2(-0DA?H1>2E;;E,-<0#'F=A
@r2968
CAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTNAAACAGTACNACCCGAACAC
+
=C+><)>(/-F/?5FDB@,#3=$-*).B=?.:=-?;@66B##!,EC0+"E0;=F,2:53G*6#'.1&)'%(D"@+*D<F@H4!D>!%H9268?H#.G0;A;B$7#%386@#0>?AD<!F;24"2GB=EA/CDF'-'E*<"G68"?=05"(@#G;-49(;8/
@r2969
TTCGTGTGAAAAATGGGGCTGAAGCCATCCGGGCACTGGCCACNCAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGANTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTTCCAGTATGGTG
+
.:/@86<F*+17*8(1+9&!75B<&C98B*GH++B!"G.<6DA><G')<3!+14'*10'3H;.!6,=5-G*660"3.?/8265.+,FC-03'H>#&5"0=,(?9:6H=:2":%94574A40!G%/;,A/@=@G5(8AHBD%7-6.7$E<-::(@B0@*1@,7,4F&G#:4#/H0:&!C1&7$$983$>EC8-5#*B?,5636,=F5G68.6)'7#@B8?4@C6.78&,-8A+;!0E9#C,F#2'0&.@6)3;&9(B+H-F<E4@1%#'5:*E.C!@?C7B7-C*)952(=8F,F?'&/H=.FB=A8*$7*<C"-;'9:"GB?('<*>';=*2B,=%?/1!<#GB!*<
@r2970
CTCCTCCTGCGATCCCTGCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACNTCTGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCA
+
?&F@AHE&;7-10BH1B<C60H1-C5%5<@"1(G'"G"5/797!"$"DH92?51C-C8$A6G>"E":B"9(5),F$9601/!C8A>3>6F$"5*,@90,?"0.2
@r2971
TCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGNAGGATAAAGCCGCCATGTGCATGNTGCCTGCACAGTTCACCGACGTGGC
+
1;5-HE66:(=G64'"&6%*:5G5#C!0)FA,+/0A?$'HF%"!-==7+DF3+@)6(BCE>'94&D+>GC)+#H7B97@*0((5;0&%#8-==6GA*CH'<3D$A25';=::
@r2972
ACANTGATTCTGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGA
+
(($#')&*$)(+$!*$$"!+'*+&&)(+$'&((+%"'!#"($)+$(*"&&#)!'#$#*&+&$'+"')%%***+"'!!!&#%
@r2973
ANGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAACATGCA
+
$'!+'"+!**"(+(++&+*%*(#)$$!#$$&+%+($*$!!#&(%&"&)+*))*%&&!#&($(
@r2974
GTCAGCCAAGTTAATCAGATCAACACTCAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATNTAACAACAAACCATGTCGCTGCCACTCGCGCAG
+
>/*5E($-B/+9C?<1%0)2E7*GEH9/)!F)!G"G2D??9;<1953B4?D10(>ACB,,>'!#25';5CB?'(00,GA/)@808?/EE;9!)(2F72
@r2975
CTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCCT
+
-7&!4HF.#=>F/1>2G(3C#96<>C%D.<19:-F-%)B!//=H'%83+
@r2976
ACGGGCATTTCAGTTCAAGGCCGTNGCCGTCACTGCATAAACCAN
+
:51-2,B::*$6%FB!A88@07)D@5.2%6E,"1545&6.?!;?G
@r2977
ATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAA
+
*A:"<<(C>0H>D/=7B3=DG,C=-E0*B3##H>'.);5-HD()=50B77+8+%
@r2978
AGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAA
+
E&;4!*,$*1(B1*D@+?#G!B!)D='(G0F)G7+'2#&C2,28B=?!"H-%
@r2979
CCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTG
+
03B"++7D9"97;#+F(?60>26A>&'5B7661>FA)1@".H!17-:$).)E-13,
@r2980
TTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTC
+
*7!'8G=H(D@$,6&&C&;&!/H)>2:#=*+;6:98@>.<1-"+CH?@(<#=@:"!/6<'
@r2981
CCACCTGACAGTNTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTNGNAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATNGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGNCTCCCAGCTGGACCGCTNCGAAATGCGCGT
+
2);)5:A(*01C3B,G(3/*7>#E;%>9&E5B'DD5#58*#6#>,?$5>0/15."3)92%G'@?25-@B.>69%67$0=0B("/!<-##6:95?6<411-@006H4$F#E>E:"E"A8D$=@/"0B?+)912/2%5*,7'9=:>,+%<<=;$'3%-A1;72,A+(#G71$/-+-$-0/<+1@)69E.C?$$8DA,B0!)=<5"%,&$*AF<";D:"-795(24GB('0)3,=),30323?+-<;)CC-0C6%9-$$>2*8H$:F!@82:*),%&/:E%G='
@r2982
GTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCNACTGCTTGATGACATTCCTTTCCCGATTATAAAATCTGTCAGATCGGCGGCCCGAAAAC
+
5=1E'4!*#?<!=7D'B>8GC<#5B;"G.1D!>D8?5$:D29*=83@67G@4+-7B-B>#G84"';;!B#*G="DEE<%>$C$#5A0%G732-<'(A,3D0?1''1$
@r2983
ATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATANAGTCTTGCAGACAAACTGCNCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGC
+
19#"G154*BF71&>!G;-&H<.=&&H=&D$*D35'18B>'813DED'0)9?'9/+:"?,87/D'$?;GFD:&:(&',D52;%H*A4-'486(#81G=G'FC0!3'G/5<@,?0<6!>2@/A(HG*6?,!8(>>=('4%;,!72<&A&>9'
@r2984
AAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGNCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGNCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTNACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAAAGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCNCCGATGCCCAGATAGCGCCAGCTTGG
+
G-.<!8+#%,B/;A//$?D?#3+@03EA+&#1>(9;BE/!028!./7059A&12=2E#G9$CGA9G"&20B"F0D2<H>0A;?5%@-3,B6A7,1-"5!>B.,@H:#F,@41H71?,1E:"!/0&+B1=*+0$03*72)/8+6:."?)::4@61'H.:1"/*"3=B&B<:,D50%);A%,43G$(,1:4>!&H%0"?@0;)G4.G:A)B0GA(7C/9.$D?A/+5C/-:,+(#<8?##E41'19+?,.8H&;*&)8E,$6=(;#/C6,8+B/;,5?E-8!GBC=-FD9A6(@?"52@@!4G:7+:H#'%:1$#,(6CBC=5&;+F=+)@**!1'C-51:<)H:,2-?'$49!5&09H'>!+>>4A@4?&*?;")1ED7#%F55,3@C<:9*HB:3D<)./A8-%7?"-A4G6+3'+8.>)-)B0;/>)>)6:(</!"
@r2985
TTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAANCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGAGAAAACGCACGTTTACCATGATGATTCGG
+
@7;6$/+?%(:)=D*+)<.,-3?>E45/8'-*.0'0G<C:')32"=*79:8?AE/-G1+1%!6#(@&;GF4G,:8%3$,DC;,90<56,)!9>321FA4:3C.G)*DD"!/?+%D=7@/",+E$1?;GE4;-!,5H%"G)2%:(CA.<9)%/HG#%?H!-4?D%,+#93B+G%D+F.>B/(54=E+?!G"28HF?%=,<0'<E<B;E9!A>F<-)B-&7G/8+$4G4*0A07H@G$H34E7+<.+:4C('*,,)03#+.&=
@r2986
ACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCG
+
5+$%#A",&+2!?.$=+!;E>?1H!=.9<8C,?C4H)!$(06@9@0C+',3-62AC.#1E'""D0#CC6"3-?.($;?*3/4C+<26082'$4D224.6&-#.%8@:!)##)'+4<>.'%C,='?<!.:6=(
@r2987
CAACGACGGACGCTGCCGGATTAATCTGTACACCTGAACTCCACGCCACTGAGGTATGCCGCATTGCACT
+
<01='&:&)817")=@2&,04*(;#6E@G(4:6FA'/@8C-$G'$+G@$)$0;+5*F-9;6*="(3,A:=
@r2988
TCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCC
+
&;FA)A+0>A,E?A=$#(;AE+@'0HC-C-)<0<?DE("@9(E6<2#'*G33'/;H9"@1()?%@:=,"457D%>',8-9H,;C#.7@*8"5#@7(.,87A
@r2989
AANNNCAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCAGGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGC
+
'(!!#'+!!)!"*$&++*)%!!!&*+"&(+"&+"&!)!#)"$&$+)**%#(*&#"#'""+$*!&$#%("##&#'&#*((&"!$'!$*!)'#&&+)(!*%&!('"**'')+'"'"$'$"$%++*'&)&%()&*'
@r2990
TATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCA
+
9>D6!$9530:<G3#===.3)7.(E!",/FH0:E/D&%;A=/9$3"#H
@r2991
AGTCCGCCTGCTGGTTCAGATACAACGTAANGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAANCACCTCGCAGTATCTGGCCT
+
B;FD.-820@)DG>?DG'C<4735F#;@(+$*.?$-+=59:B91#7?H&)=>'E323/BB2A#D&A54=%/C40BH$,;+7&<$<C"*0"('AG@
@r2992
ATTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTTTCAGCTGCATAACGCNAAAAATATATTTATCTGCTT
+
+!((&#$+&+)$&%&*$&!'#%*$%+)#"*&+(!"%&("&#('#'"#"&$(%)%&'+#'!!$'#!+('&!'*(&&*%!"#'&(%+)'&&(!%'$"*'$*#$%(+()$!!+"#)$'+%&
@r2993
GCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGA
+
4A:DD%H2:;#*07C./5%"3@E*>AG5B>D&7%/A%3;#F;)*!>D%.D$,(#909B+"?0D@@558C&B37(@
@r2994
CGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCNGGGTATTTCCCGGCCTTTCTGTT
+
,-FF%3*C&!7H&*F74:.;!14)#E<"C<BF<8,C'D/,47(H;$#98HG.=;BFH.F31
@r2995
ATGTGTGCNTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTC
+
'+!(%)&$(''%%"''+&(&"$()!"+**#+($+'**+(#&+!$$)$*$()!!#*(+%#+(%($'&)$$*++#$!
@r2996
CATGTGCTGGAAGTTCACGTGTGNGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGNCTACACCAGCGCGAAGACGATGTAAAAACGATNAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGA
+
B$F5C$H"6"(79&D@!-@:E>=54,(>!/*%@C(G"/84#,&;#%/;4?7##&!G=>D78=5F>@'+%A:)D,+7B08B1"4A')>)55!32C@<C@%A''00%,H&E/G5#9$2G379(/E>&1>,FD%,=B8@+B1*F-!)+")$/!81/:@&11@B8&8!#0GE-E8)-"H0#;"8+D;0>+*A8:!
@r2997
CGGACNTTATGATNTAGCGTGAAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATNAATTATCANAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTC
+
)'($((+!%&***)*+%""#('$&'$(!)*%%&#%#)!&%$#!"(+('$%#$$&)!+#'+%)$#&%&'+*&#$#+(%%+"()!(()$#)"&*'"(')$&&(&*$#'""(!(%"$'#''+*)+'$&%!$)
@r2998
NNGNGNGCAGGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCT
+
""'&#!#"!#%+&''"'"(!+$)&("")$#)%%+""**%%"$!)!%$%$+%+)$''*$(*#&$*+%+!&#(('*)&%+!#%
@r2999
TCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGAT
+
C+1A)=B"$9',!D4"9)(F84=*A4B$BC9>G&#$@"?'@BDDD2"',H
@r3000
CNATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCA
+
''(6%0@9F,42$5(12.4F1G+&-D87G-'HC'#<(H=/,-"@95-&ED=<$
@r3001
NAGNATGTGCTCTGGCCGGAGGCTGCCATCGACGAGACGAAAAAACGGNCCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGAAANTTAANTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCGCTCAC
+
!'%(($()$+&&"+'$$""%$$&*)#'$#)&$!)#!!%$!&)%#%(%$((+%($#"%+'!'')&!&!$#**&""*!+(!"*+&#*"$#%(+)*'*##*%''#$)($"#'"+!+!#%%""#+*&(+"(&&+")#"&+%*%!+)$"#"*+'"&#%''"(%(%#$$#)+('%##&"#*&*"**!&+')!*+"#'%))##))#"+*(&(&"'"#$$!())'*"$+$#*'#%%"&!"&+'*("&+*!*#()'(%("+(("+))#&(%))$(''
@r3002
TCTCACNCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGNCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAG
+
##((%&!*+$&+*&+"*#+'%)')%(&!#$%&$&+"*"")*'*+&&&&*($!'$!*"'"!*!#$('+++++&))'!*("&+*$$%*""($&%(%+""+#+()!+'#*(!#'!+*)&(+(#%$$%#+%"$&')'")+(*&
@r3003
GGTGGCGGGGGCATTTGACTGCGNTGACATCATCGCCCGTGTGCG
+
.H.&>.'CDG#%0-)6)++>15#>/H9"0<;-;5-H57E&&=;0B
@r3004
AAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTNGGTGTACCTCATCTTCTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACG
+
7?B16.H).!4&>$G;@%2(,(3,=HD3B$:$&3B$#B#!8HF=06'/.F.B!E8F&4HC$>&EE'G8.@8F5@;97BB"9:+-,A9)+401>*$=4
@r3005
TCCCAGCCACACGCTGCATGACATGCNACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGNAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGGCGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCCCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACA
+
-0C54%H""&"D$+>-*3",3G$0-#%CD4BBDD84*%*?33D#33.6'66-0D=;439G%+="B&=1+-FB)%E#7/,B6C6G/;$-<(FEF791;;?)(*+@!+EFE@D.H@EH7?G19)DH==&B4A3%5A?:$$/7&!6&F#1EAD1/-:B"A+4D:$9D;4:A%&2B!+GF9;?5E#5BG,H,/8C291*8+6+00.@G9922!.$?=+56$5*:7&$C6-BG="9+B81E$>)?)@GF5FBDF/3(3D<7$!H-C!?=/CF+8#$&99B0GGE40H>3:&)*=3G&#2+=D>)G>8"?>>FH8;A;B.=F'<*11)@G00BC?<-7,.$)><5;8-.7A&E$250=C,+("C<F#9<--.0>4*C9.436-*2:6.)/HB/$'H,HG+DC8)($7)-+)GEH&!.@&)G7GEC?>>>*'A2:62,0;0*'H<F4C10&&A%C:DF*?!412-%"-&)4C3F;?!?2;C?@@5);/H,8;4CF".
@r3006
TGTTATCCCGGTGCTTGTTGCCATACCACGGGGCCAGCGCC
+
6,*?"2;5E+/8+@>041C2/+.36;4&$D;-H>;*>40#4
@r3007
TTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCNGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGG
+
7=*#+?6.6@4C+)F,)=E;5!4?B,CBC0C080(*FEAH05%<+6+(!:3G*$/4(G443<,CC>6+,!/D*D('&>!HG?:3'E+9$D=,'8CB'6+:G#F0G+0)'%(.386,)&;$10D'#;5.:%@<#,29#
@r3008
GGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTG
+
#4,9/6%.'&03$"7.E@A1.!2+5!=1*1HC<#1C'E%:-1'@G-6%G=.4*$/*>%!C:<#80"$=8)=$$:"/5E0)6H(,ED@=(&3+3<=481FC@B1=?*!=7/:62(.-"&(FC2D3;>7)>96%#1
@r3009
ANANGTATGTAATAGAGAGTAACTTAAAAGAGANATCCTGTGTTGC
+
*))"+"!%#))**!"(&$+'*%(#'"(#&%$$***"(*+%*+$#'#
@r3010
ATCAGAAATAGAAGAATTACAGCGACANAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTNCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGN
+
BH/@"77A8G(7*$#!@.?$":A!+#)';+"9*;@$):1)(<8,<5:@;)9F,7H<)<??6+C.794-/.52'!7!&19*#6=&'2;;/E=&F1141H1"1-)/#D(8@)&4'F9%1#%C67(C@G!:E;%>=',9GDE&3G4:5@,-@+-BCG#,@,@;-H;1993%,#+G%D05HDF8'1?.@
@r3011
CAAAATNTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGT
+
$!##)#"+&$'!%*!$)*&*'$*"+%#)"&!+&+#+!+!!%($+$%+$$*%"(!'"(#)'($$!*#$("&!$
@r3012
CCATGNTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATANCCGTCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTNTTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTG
+
6GB3#>3E%5+'7-'>8>GE5&*-)32C$,6H5C<8<A3B<$278C0"<F5:7D0:$;.3G#,:)EE,"F?-.H21/?G!$"B:?+/.@$:%!5-9#.#)7$H/57'"FEE)FH60$D2>&)84)8HD96,5=H'7)",8=4F@+F"(30.8'A4'@%).H",?%4&3;9."3A.$#8"3+!A$1%!%;3+!!,+4(8#/599EE!"2&04AD1+2)H+$59AG/8,H+$@G)#";F6=(F5(;BGH8%#&=
@r3013
ATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTT
+
:-,A%#)%*E@3;,C<;*,/;0D"'=E*:%5B'HB8):#69:
@r3014
TGTGGTGAANATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCAC
+
H;HH$19G9%4F)1'28H*D2)=&C&=-C76--)7B*(@&=').5D"-/-<<"@/?/$D&&(<>A%!9CD21B&/94%3-90D7:B+8*9<3*B*'/8=@9A&@#.E<<?>C.6,;"$%3-,G<;%0C@H(+C*G01?:0&<D3'.H$&&B8?>C$>';*)12!+E2"+5-'
@r3015
GCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCNG
+
@7?7D?=81CB!<=CG:F=&8,*!8920:')B"09=9/F9@-$19C56D@/3/FHCA.4
@r3016
GTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGT
+
>)'216+4D;>)D21D17F(.E@(.F'!,B%2"/8D62G76>FD:&2H-@"->!,!?2
@r3017
GNTCTTCCCTGGTAGCAAGCCGGTNATACACCGTTCGCCAGACCTTACCTTCGATAANCAGAAGANCTGCCCGTGCCAATTTAGCCGCGGCCTGATTTATGATGGTTACTGTTGAGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTGCCCAGGTAATGAATAATTGCCCCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGAGAGGGAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTANTTCTCGCAGTCATAT
+
0+<36*D!D;-:E#:0D6B@@!.2A*:8>!.F4*.7CE@(B3@!",)EE))32-GD/+6)$@/"3*7*F9-+B805&::5=1--0$:*/"6G32A5&2,A+3#3D';.C):**A;'1.H=@"4-&4<9:*;DH-1-$-%+7'--!5:/$+*%=.27A!A4!#H5,)%"<.16*'@7%7C8,>,#84?91?3C6//H>8E)9<7G-?HF7C9*24EE$'9"*12H4E!AEG99F%<;H'G7@AA4<0@B(/$,3<F307,)H-##82B*6-5@>42GB*B7D8A./9B'E,,>0-A<)=09"$/C@.5F(!$)$0.(>>B*&158;><(+H3F%E,;.6(-+1%"
@r3018
NGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGNGATGTTATCTA
+
$2E;7C*:"7<,=?'&.%!06&1-8;E>0CH3*;<.=G3"<8$""5A8=*H=<
@r3019
TTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGC
+
(679+>7A!.7&,90$8!'??.0)/&94'?E%,*2.<(6A)-F:B.#
@r3020
GCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGGACTTAGCTTTGATTTCTGCGATCTT
+
HA84/(;1"0;E53!<46,<4/,&,73*-A00E,&63GH?<'&<HCH:/(;"AG,F,!?3>=:-#?.C78#'5?.0C=-;668*C#)
@r3021
NTAATAGCTTCTGTGCGCCGGACGTNGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAANGGCACGGGCAGGTCTTCTGGTT
+
&+*%&")*#()&")&'('+"!%$#&+)%%)%#)!)#*'"++#*"(#""*)&**'(''%)#"*&&""("**''#&)$)"#!#)#%*)$+(!%$#(!#**%*"
@r3022
NGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGNCCGGCTGACAAGCGTGCCGGACAC
+
!#?F$?1#5D'&F-,4@+)FE;31.CDD<@48E;.$B&F<&*6<E5E2?50!=!>2;)6>8BHA(?-425>>:HH1&AD6E6$0>?
@r3023
TTTTGCGGAAAATNATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCANGTGCGCCGATCCCGTGGCCATCAGATATCGTTCC
+
>G.B;?6!+&=(9257E9!C'G81+"8"@&3<HA"=A&8"%=H/H6?8D,A/(37*?6=!>3*<G9G96ED>)*5C88*&B=6,6,EH7!.&*-C)>;(1B/360AB14.CB./B+#11,%=D6723>*FF..2#=C+B9'*)H1".4(A47!(!)2/CAE)
@r3024
TACTTGGTTCTCTCCAGAGGTTCATTACTGANCACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCNTCAAACT
+
(%+*!+++(%%#)"!&")%(()'&$(!+#%"+()'!(*&)$&**$&!'(+)&(!+#"&&&)%'&'$$"+!+!%"&#%$)'
@r3025
TCCAGCATGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAG
+
'*(($&++#!$##&##'%$"*#$#"&%*!*+)*))&"(!$&+"#*)*#&$)$'*&"($$'"%$!&+'($#*)(')"(!#&&$"#)$#"(*(#'&!$"(""#+#
@r3026
TAATTTACGGGTGATTCGTTCAAGTGAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTNCTTAT
+
56/'3=F+?'52F56?GC+",/2)<8:54G>64:&2*;C;-.B2$')G3$B.)&G9EA"1&F!*.=FF/D"39&-F+<+=*,=%*;2>$768
@r3027
TACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACC
+
7+<9D("9-92A.!,*$"+!+GH*C1!=ED@A-0+7G!E)#C962?4.C)="B#22;AG!8*?A'B5%G.<?'@-&(G;C7H757<<)
@r3028
ATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGC
+
0;@5552>?D2BD>;;('4$D4/1+<>59DB=/5@&8+)(!%5FE+&'H'
@r3029
TNTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGAAGTGCATAC
+
("&+*!%!*&)')+'"#'%+&!*%$($*()%!!*)%))+#&'%&""&+()(
@r3030
GGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGA
+
23/G<75FE99/A6GF>G%@#6.."/5C,@-!3?&A090292(
@r3031
ATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCC
+
..!4-1.131,B+A=2F/$@C2"927))7?)>'2'"<E.3/2H9H
@r3032
GCGCTCTCTNAAAATAGCCATCACCAAAGCGCACNTTTCTAACAGAAGGGACCGAAGCCACATNCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGG
+
!&'%$$"'%#+%*!*!$!*"#%+(!&!"&!+'&&(*$++&'#&+(*!$%*+")"#%""!$(*'*"$($'!"#%(%)$'&+(*'"(*'"*!*(+$%)&+#)$"+%('++(%$)&$
@r3033
GGACATTATCCTGCAGCGTACCGGGATTGATGTGAGAGCTGTCGAACAGGGGGAT
+
664>;4=3G)05(1F,@%G'<(F=1+%;4<5%.D#>EA,D/283H=@AE,%0:@E
@r3034
GACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCNG
+
)2+0H(,8983B26&4,$4!<280&0064*7:;8E95;.&C2<%<<-=.15.$,*;0-<?7#8H&H$6
@r3035
CCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCT
+
%,$-2'#.F9:#4C9F-1>-7,.,?.;5)%42&E!0DBGH6@>'1/@;H@<
@r3036
ACTCAATTACTGCAATGNCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTNGGAGG
+
@(##%2C'/4>C0@',-A4>*!<D9$(GH8G%?-!=8&F02F1;'5@B.)HC*H)C),H!
@r3037
ATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCANGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGACTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAA
+
>*@C7/:!).40*=,$.C&&F#,>>G9=1D>$8B3</837+?(87+1$,1+EF;-A3CG;443)E@,9DA3/$26E;#7'.=5=B3+75%$&4B>='$'B@0-%(:(+?A%&4$)($(;&4"/(16#FC/9=D?(C*5A$*E41928"/2/GF68(2);,*.0"69)08'!<)1#*F'5G"1!!.=$C1.8#FH,*A?'!A@4?.(,BF.3?-89D.6%0B1C3H*>%'+(2@");CG*&7/C88;F@<1BF1-5>9'<C!G:B;=H>"-'6B8@%05<264<'*D;)7A.9B
@r3038
TGGGCGATTTGGTTGATCGTGGTGCAGAGANCGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGNACGTGGAAACCAT
+
-HA=&?<&AE!-=5@'51*=%4&F)86/.2#6E8++%<2FFC?>6?0'A5A.0D0-+)!4$"?9&HGD&:7%5&8A4-#7!A%E@"*<6
@r3039
CCTNNCGCTCNNATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGA
+
%"&!!$)"!*"$*++"!*%+""*#$!&+'!##')%!)$%&*!'(#!"*"%''#()+'*'!"!$($)')!*+('$%"%*(+!+(%*)(#!'(&&*#%(*(%&%)+"(&$+!$($$'(&#($)*")
@r3040
NNNCNNTGNTNTTGGCNGATGNNGNNNNNAGANNCNGANTNACANNNCGNCNGNCCNNANANCGTTNNTCNTNTNGCNTNTGNCAGCNNCCNCNCNNGNCCCATNNTNANAATNGNGTNT
+
!!!"$!!"!$"!#$###$!$"$#!##!!"!#!"###$$"#$""$$!!$$#"##$""!!!!$"!$$$!$$$!"$$#$""$!$"$"#"""!#$!##$!#!"$!$$$!#!$##"!"#!!"!!!
@r3041
AGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGNAGGGAAATACAACCGACAGATGTAT
+
54!0+%,D4.=$!.0!=60,81$(0G?7!*0G!C,+7:62)",,,5$/+@,#1)9%"H;D)H75%H"!H7<C),7$=*36C%1)AD2
@r3042
GAGGGAAGAACGCGGGATGTTCATTCTNCNTCACTTNTAATTGATG
+
++#<?.1+8C6?)-<?#A#1!1!#'AF.B?@<E+G6!(3B96$G3,
@r3043
TACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATAT
+
(EF0')-A-13E'1''$1E<:917+B6$.;F/2)6+;6H&!>,F:"+5$2?@3BHB8-?6618/#
@r3044
CCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCNGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAA
+
4@AD:%.3";H0*.;>(!D-*$!(<=H;/B6#:A,7%33D(HE&B-998H-9!6*?!./B!*0!(2H9D--#:8;E%8==;7708;?5+7"827H"+A95:#A*@.;+A7?B?9*1-'>,B2(C0*%D?9BG9'<&@/4#@0'.23<*2:/2'0?<=@"$CGH
@r3045
CATACACTTGCTCCTTTCAGTCCGAGCTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCT
+
AG00D,A;"#0@BB7C,)8<;?+71&<#9:8=C92;B/8>!C3$==(*?<(2.FE'$,E6332H3=6".9E,@.1(;<(=
@r3046
CACCACTTATTATCGCAGTCCNTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGANAGGATTAGAAGGTCGAACCGTTTTA
+
75.;"5A826!)%-$=2C*C;;"@>-1!##4(B"C!FD>6G3<%B=."#75<4G1E%&D<8%>$B)114$:/#+<:,GH:H+?"B*!B"H/<7&(+3;-
@r3047
AATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTG
+
@53/!A'&*.*A27#9&=7-79()+#:&;<5H/+;)FAB!#&/E@DG+$*
@r3048
NTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATAC
+
$>:<26C(F!6B/-*3.&DB)'9D=08!HF'&)?F!.D)H;2.73H':E:>3F:73&A?E,H/,1?G-?1=#0E.6'B0"577<42@%#7.+C"?2&4*76.3&A2!(F!&D#;E,:4>E+.4G!>+B;"6=-'"E2@:D4@'&%;
@r3049
NTAACATTTATTATTCAAAAAAACAAAAACCAGCTTATAGGATATGACATTTGGTATAACAATAACGTTATTGAAAAATGGAAAAATGATC
+
!;(40:40H+9,0%%!+DC;<:*>/"2)"2F);$FB5#566;>:C*3F24"><37-9:+.67>'9$=;+;&F?CG@,#'42%C29)DE;@'
@r3050
GGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTG
+
E,7)&0)4,1!8,G(#$%?4((3HFGGE8H2'):)&D:/3D8%897GC%6G#1>*%3-G:A-:;.
@r3051
CTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCANGTGTTTTTACAACCANTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTACATCGAATTAGGG
+
G7&1D/"G91@+0=FFB!<.02(4&GB:8,B8=5#,75*'H*1!56?EAB"+.C*&D!,&G?4&>124:G/7;EE@$:DB';>A#..>2C@+/#?;*)*&A;%%)&38*4;5$=3$:<@1%*A>42?)E*/'6*C0@G08"8-8F@7995A7!5(60F%-5=@$444(",#$@;;C%3"DC"9,.B2?=A*6E'1**)D)H'7'EF304925$::@=)GB&,!9,5)-9&H#'0D?2#053@)$'?+A())!'%(&G6H-"*.0+AD3CFG8>H->A*5#E6@%$8EH*6:%AG+3*F>;B0?E10F0,$;37*%:2*@%G;E*-!5=!/#4H=;#H.774E3<5F1(6D4.&4
@r3052
NTTTCCCCCTCCGGCGTGCTTACCACGAANCCGGACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCT
+
$0+(5/%/:>!+783?(;3??",56EG+/H,B3>*94#$%1.+:07/+CE<=+G@))(();:C(EA<*0$!>HFB@E1
@r3053
ATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACAT
+
C=@.8$@07/F.95>!ED/&H207C77H6(*(*46*&%;7D'12;
@r3054
TATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAACGGAATTTCGCC
+
43C@44'%"1BHEC&5'?><.BC-81H)@9"<GD*@GGA./(G%8B(#')1,*#0B,1@/B-0CH"@014E!$-6CHG,("1/(2;1#D3-,?7#@@<")7*;A!:'7->&23>D,>B(A8+8@<CG+8C@@GH*4.5>!>B?A3E+30+7$E6'H9,49$#0=2!0B);1#*+3G#408#88*A21.?*5=F.)D!7/4:!#(3C-4C6!A0CG9"H)?<H?<
@r3055
GCAGACAGCTGGCGACGTTGCGCCCCCTCCTCCAGTACCGCGAACTGACTCTCNGCCTTCCACAAATCCCGGNGCTGCTGGCTGATTTTCTCATTTNCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGT
+
G*9E45A">+@=CD>F*D4E.D('A1=HG=%C=(@47@(&9?'%,D+H%638(;F%7D1"12)-?:*H8?.AF.8?6,A6F7FB;G2E1DC6#*<*046&('<*<'H#>B#D:945?&:+,7;(:91$=:(CC/?7&H-E%8+#8'G;4G)$0FG97H8)4E*,5BA6</GD(&C(C+2'*A7GE&/"213=;E>(F#<?#:57>6(7G5()C24.8;?F?
@r3056
GNCCGGCATGACANAGCGANGCAGGGGACNTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGNCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGN
+
'#+"$*#()#)+&%&!&$++#')(%#((&&%"!(+**%&!)*%+')+")(+*$!+*(&#$&(%*'#)'!'((%$"**$('"&')+#'&&'(!((#*$(+""(*)$#!%()##$++('("$)$"&'+
@r3057
GCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCT
+
AGCFA;$85;;E),-)A#2D>/%;>3"H>57@+*7E44%0#>A1(A$F10A"6H40?D%:H8*&G:*.H2<H#F4?:2;C9:G7!E'=9)<+5))4@,&6
@r3058
GCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGG
+
-@)0D?%-&4B8F5:A*/-G6#'(3,',G?;,+)C0!*A#F2'
@r3059
NGNCTGNAACCCNGNNCNTNNNNACNNGNCTNNNNGNANNGCNNGCNNAGNNGGCNCTANGTNTTGTCTNATCANNNNATANCCAGNNNCANANCNAGTANTN
+
!"!###"##!"!$$#!""$!!"!!$!$$#!#$$!!"##""!$"#$#""$#!#""!!!#$!$"##!!"$#"#$"#!"$!$$$#"#$"!"$#""###$$"!!$#$
@r3060
ATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACC
+
%<>8E0,0'5&.$$:=1G2%4D7>$69;->4:B6)%B+;,A*+67CE0DDE@-,
@r3061
ACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTT
+
4&#(!%$*%:25=CFE.5C*&<"(1:5,>C2G432+)='"BF-#D?<*-/3,!=G&A(>6+"&C*;'1G:"EB'HAD<,7&!DC>7
@r3062
CTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGC
+
&*(3"'5)$.EC(&/6/5//416'7F.1DH%8;E&G2>4<!!(B*;@*40#?,>?@H+=;
@r3063
ATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGC
+
49*0@911<+@%+%9&C9,?7/F5&1?.+9"FA09$';),1A-;D==G$>)@'$H7@>G3$!3C%(,H9%A.."6/E8;2B9@7,+&;H*2&5G4>):2:EC$!:1'$7!#/"@E1#=)B&%,.@#9$*A*GG#<
@r3064
TTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCA
+
>!!""?B6%("%1%C(+'D#$8D!>)4H5+#@>087C:13((?!46A9C69?%;FA*"F36<EB.!6B73770;
@r3065
CNTGCNNGNNATGTCNCNNGCGGTGACTTNCCNNNNCTNNAAACACANTTNNGTNNCANNNNTNAGTANAGANACNNNGNGCNTNCNANAGTTTCNANCNNNNCTGTCNCTATAGNNNATCGCGACANCNTNNGNANNNNACNNGNNNNCTGNNNANNANCANNNNNCTTNCNNGNNNNGNGANTNAG
+
"!"$##"#""$!"""!$#"!!#$!!$$$!!$##!#!$!$"$!!$$#$!$$$"""$"!!!!##""#"$#!!##$#"!#!$!$##"!!"$!"#$$$#!$!#""!!#$!#"!"!"#!#!!"#"##"#"!#"$!##!"$#$!"!$$"!$!"##!#$$!$"#""!$"!!"!!#$$!""$#$$"!"""$$$$##
@r3066
GAGGCCGCAANGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGTCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCANGAGATGCTGATTAAGGCAGAGGCTGCGTATAAG
+
FAGD75A;8$?6*3/4B01G57$:'+5(49'/28/9?D?!,72DF74H=8A;*(?4/8D(/$>-8?0G&D'B1/#=,ACCGBC8/1<-@=8E$(HB570$?97*%DHDA+=%4+"@#7518D?B;0#5+9A*H9"/#G1($%-B:.7.>2/C.?7#5A;3#3*7F)B787:6D=@DH16/
@r3067
CTGCCAAAAATAAAGGCCACTATCCGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCT
+
$/,1.C/=5(!6=!!@#)02&E1)=+;/)=+!1DD)CD*,$A%)%4>D>'-?7FB#97%='@0'>?4B,C,&-.+=*?0E=!$!9'FE/G-E?0@%%%8,4*7400E&(,
@r3068
TTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGA
+
-E-4/12G-B:;BE$!5G,G1<+01E$%A;41-A)?!/5/5H@AFB-
@r3069
GATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGNGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCA
+
EH1*>:0HD&$0G?,B@@H4",?($+'B0.2*(B(,:0A,5>8FH/C-$B'32,,*G6.:&F-"ED/=@E!7@6(1F3C5"C3G$C1;<45()GEH<%?H;@2&6,&41+5!
@r3070
GAAAGATGGNAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCGGCGCTTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAANTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTAAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTCGATGAACGGGAAAGANACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAA
+
8)@:CE'(HF(42BEG6&'/5G5?7/@5$%'=*,'2"C8H;$B1G0=/#B(F3A70*BF8+8C7-;H/D%-93/AC'$%*1G4G+6&@2E@4#'->F3E!EHF6'?CFG=D0%C5=-.(D-2-282'C$<B#+()F7E89B/?=*A2$//'FC-A?19?A@F;G(+%E?.-;=8;-F.C4B-0C$"#$C.51+,B,;4"(@,4>?*+0B!C#1G+-B#8,;<'44.,?@#D;)=%F013)+A61>A'FA2"G)-%A<@-!/7"7.EE1)(#8:"D99=!3:66+9=)1"!$@&96/1(-6'325.3,?E?;DAE$4<FB78H<&/)#61-&&;:72E2&C,F%1@/!HC&61*/GFEH$C;!('G+F5A$(%5)(;$G8B6>;&B%#->G<4*!:3/6::,+%;5.-8(/3D?)CB8F66H:CF$0'$?H:/E>8?)F:7F(302>2
@r3071
ATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGG
+
'"H-"5<%D)G.$+E#6<<%"+)<@.4E44='3A*9@8*;>&96<0?10>=BF7;77??H;!/B8E7B'B%!<$2'H<9A33AF$H8?&?7:5&/*<-4#@6;**(ADDE*#?..(.&6+4AG"30;G#EC<)!BG2$77"1#"83)"?*@)D6+B<F,%D6-76
@r3072
AAAAGAATCTGACGTAAAAACCTTCACCCANACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCG
+
:6=*B?&1'4*+.$()(9;31:4:G3*A>H>6''$BF>;0@F;C!(G'+,5"(0F78"4!"DG./.,D;?9,8><D@+%9-3$':A2:>;6++9?/#,-772/F="=6235FHD$F%@+>EDF,
@r3073
GCTGTCACGCCTGCCTGTTGCTTGTTACGNTTGTACCTCGAGTGGCGTCCACGTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCTCGTTCACGCATCAGGCGGATATCGNTAGCCCACCCAGCAAAATTCNGTTTT
+
+0?8"8D6)($:";);)!,')9'@BE8";*)##*?";@<.1AGBDHAE9E5GDHE7A'<!A3(7&(#E=$A+.A55%4!/;+*724G.=/+%BF>%?B6&?;/9@:4)">/B@$F;8)-D99!$'$?$<),>=</2-3@1=CD.3B14A3@8)@E""*5@H;?D6+GB6!;5'2D>H6H&B/%B$/>9E-@0$5/2!)@,;5)(A
@r3074
CCGCCTTACCGATACTGCTGACCCAGCCNCGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCA
+
09*)='B77%62+)5E90A9F?D&;-:?/7*,$$F698F.2F0CHFA74.H@0B$,6D3@8#&<0288"/=!6+!B*A>*=D2*4B;$;
@r3075
GATTTNTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTNGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCNAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGNCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCNGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAG
+
EF*#()*6AD27)%+B.##>0*C:04>&6<(,C!&@><@H@$460FF@'H-/18)+16/G=:8/BAD+4'&><6-+'@=H';'4-.!>7-=*G85-&?-(;DG2&7'5E'%*A*<4=E7@2%.2D;(DF;C:?$@17H<<7GD/71=,C.A"'E=.1;>6'92:H9%;7&$6:#F>4C7E<<79$:4%#B&%BG?7:<7(59B8&/C:A6<?+2E29A!G%+F>E2?1#7(2,;?2:@74!<8A$>/D;7B3$4)CAF=-!>B(&+<A$;'DGD9C=-F$1"=.8!/)/F.,)=B5BD/9F+)>=4"<-5&5:1:A,A&).*2(1,<%CA"3C:*G$,F"3C?1*!$;$>0(92>>>8F?G)1/A5/1*67=!>?-4&56="'#<D-C2:(-9CD$E<1.?&.5$?C21!(..86
@r3076
GACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCG
+
=@%FBEHED-&@<H+A1*.9#*"<!*&E+18##5!2*".,F@$*
@r3077
GTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAA
+
95D(8H&2>*96@;7?@33:3=D3-#:B9<+3E>6%C:.)*0*4,>'FA;56(F'="6'D5B@74*,CF4=F(*2.%(=GF%:82>".6)5A#4H6G'DB!6D'-+.2G:.4$0F(BCE3+GAB=!<HD0E0?8H(&5;1;(%<7("CB&:%9#=!0/0H(G-!6?(1+".H9+8H5#,FGCCE.F&G/)3@='$B#D'C%<6.#1<&=2(H)C",58<*&>G<+:B9//>%&5:%9!:;%:!:;B5,3>&=:B9FE.3(.G5(68,?7:*<D$D4%((BHB
@r3078
NACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAG
+
"B00&(2EG:3B8DCC-H9$2F&"*<4F:3!23-'7?)'/#0"A"AD1%A?#$,-3*-)"F)'"E:767&B"/.G;.#)2%3?0.'/!07.!,.>/?"<<)":
@r3079
AAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATC
+
;A,,#(FF9G'?E,8&A)>9>,BG."-8E'+DA.+<A-@F:+;+H8?1:5'4A:=/4,3HE8.$6"H:FH-&1A@3:+,0!7&E?6>).G/2,/*,%(3)2").&;)1>.FF%F@H>)#497)1=0"4?4%$4$1%%=)D9+(A
@r3080
CTACTAAATCCTGAATAGNTTTAAGAAGGTTATGTTTAANACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGNGCTTACTTCTTCTTTTTGACCTAC
+
,3(."2D(D$H9/@D'/G<($=;F'7F6!B)!7@>$F6+"&',!E=9;:1-H/97G!!9<4<&&??H:FF9$%C@5-BAB$E$D3=,,<83D0$39DC06+:@);"*"0AF(D6G<'?*,!1$;&!64A/!'**A1@!F9.-C5('A<!5G*,+D-?)")#;!-80>&>5,9AH)%&!$D2-
@r3081
CATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCNCCTTTCTCGTTGGGTCCGCATCCTCAAGCGC
+
:9F:.A1E*,<H:8:6/+?7$(@($>!7#DE/<3G7-!$67,-1:1#0?.0?2776CH3@H#H4A/E<:E:+1.5?HFD:H*/6/$4,;'DH03:%%05*>7D(8("!%#&G*G'
@r3082
TTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGNGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGA
+
GG87"6+%3H"D5&2B6H>:C<=57'D@$.:9!!'00/F:"!38/0"<825)E<=?3"61A*3")*"$,=()-6'0.G#0%=<$>CA5$#%)2!),;<(60B(7$=;+-1HCAED'3/
@r3083
TGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATAATAATGTGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAACTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAANGCGGGATGTTCATTCTTGATCACTTTTAATTGATGTATATGCTCTCTNTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCA
+
<?474,%C175@"4F"4C0BB*7A6F7B&$/!!!3E.F.2$<,85D<@:276A-E15&51H.9$92.!<=1)&/?4:&F?,(.G2)+?/'D(:F=C$,F8D675*B,(H5)(924H:=%":6(=82A-<7?68&H+#3B*&>A%H2*E(G,?9'H;=8%8852@C>26*%:054978>,)"!B82<<H?950>57@(C/E@44<9@1B6;7<&62BAE04G0!D0><;@!GF5!!87D>?F25$7G/9+,GDB2<F#2>((,&3>;=/<AG/C4B&'8,D>-#:??7>,@1&<H$)-5%"A*$*',:E9D&"=$2$A3B?C9&>)-?D
@r3084
ATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGTGGACCTGCAGGATTTTATGTATGAAAACGCCCACCNTTCCCAC
+
4$D47A9*(?7!:;'>$-=2-G(@5+*>4%&*$=E*)F6B7C!<>E!3F;8'&)&((+H+2@*0>*/<,FF+5H2279>E,D1><AGC<'
@r3085
CAGCCAGCGCCTGTCGGCTCAGCGACTGTTNAACGACTGCCGCTGTTTTTTTNGCATCACTTTCCGTACCAGAA
+
D;.4)1&!*3-H1'#=G"D)!4;?+&4@)++;FCCF;H5&0A<<-'A4!@&D-@D6++>(9(./A0)5'>;:F-
@r3086
CATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTNGGCGTATATCAAAGCGCGATCAACAAGCCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGG
+
/'.B6:0F5#9#7*#6,'(D4*)80)G$)F?>(&('>BH;CG+9+73.G0+C.H).3D%2?%@)76,&,)1,9<?!6/>2/AD5@;;'(-,/6!&3"&+F"").265F<E35$1"-'9':<4;A1@<E40>-B*7G/3?D;,&0?!
@r3087
TCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTNACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCAT
+
"%9=()=EF#-.D!CFB/?CB68$2/BHH8>GB1>EE;&F+%6.9"@<)?B86<>);(E!0+B<7%&);EF?0)4=,,A;C2%,7.>=*C1B&8,G.419:;?#(04@,H>98.1D==0<=?C"D/B0/-;>*23<5:%=%
@r3088
TTGTCTTCCTGCCTCCAGTTCGGCCGGGCANTCAACATAAAAACTGA
+
*E8$-2.1*C<?14!@?-!@8,6*DFG/6?A/.<=%$+1F67?.CG0
@r3089
CGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAATGGCACCGGGA
+
D-!CH".2AF4>2&3@E@2&)H-'D8B3@-BAEA+8&9'5;:@FH+<@9H+5AG2
@r3090
GCANTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTNCACGAACCATA
+
)*&+'!#(##'%()&$&&&")&"&)"!!&!&$(+'#"'("$$('("!"
@r3091
CCCTGAAAAAGGGCATCAAATTAAACCACACCTCTGGTGTATGCATTTATTTGCATACATNCAATCAATTGNTATCTAAGGAAATACTTACATNTGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGNGAGTGCGTTGCTTCACAAAATCGCAATG
+
-,3)@4'%G1D:5E92!.749"<9:4/?A),E2;13;0A=/63AB.68'E$0")+31(E6()8D#$4/8!,A6-199C*#$33=HG1E%5=D=E-D-,9#B;4HH?2H!FC&3?1HF%//("F%E40E,FD5A?4?=6"79=:=;C8?1$37!'!%'@#91E
@r3092
GGTGCCGCCGCAATGGCCATTACCCGCGTTGCTTCATCCGCGATATCGCAGT
+
:B/8FB=&-D&=;;$#CFD43H#)0%FG-&>";0,.4D.-F73/GEB:5=#%
@r3093
GCTGGATCGTCTGATGCNGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTAACCATTACCAGCNGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCC
+
A'95/7!D89$&G2-:9>;A"C,7%D3<4,3$<H)A1F%>*%B<.7A3-D:,.A>%/,C5:F5(=;H3%-.%;-#E"/)/-&:&=;AD#2242$(!#'/9?DF.'=/8A=<&91-.><BB/@E*))505F(;+C-=$/)19%=.>,".901*C;/0.*$FFE,5GAA%2(1*E',$<-
@r3094
CAAAGCNNCNNCTGNANNNGNAATTACGANGATCGNGNTGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTNGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCANCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGCCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACNCTGATGGGATTCACACCGACTCNTTTAAGCNTGGCAATCGGCATGTTAAACGGCGTCTTCAAGGAACGATGAACNTGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTAAGGGAT
+
))*%")&*)")$()%"$!##!%'%#*$&**($)*&!'!%+!))!'$)%()&))")((#!##('(+'*&+)&#$%("!"'%""$&')!)"")%&('"*#)((")&"+"*('&"&!''"#&**'#$%!)#'&'!'%&!%!%%&"*))"')'%))#)%+!!!)))$*)!$$&)$+#'"&'")+"%&#!$)#%'&")""'&)**%+##$(#*#!'!&#'+$#*!+#"$+'"'"%'$%'&#*$')!'*!&"#'&&%))+*+&%)+"#!++'%&'"$"))!"!"(")!!)'(+!#+%))(&+!))"*'$!!"+"+*+%***)'+'$$&(#$)&'*&!*&"!'$+'*$%++'%'("*+&&'%(!%*)#+'&)(&"$!&+')(''&&))'*!"#"$!&*"&)('#)**!+$()+"&!%)$$!!%'%&$!)%#'"''""$'*&%**#+*(++)(*"(+!"%+($+*&&&*%(*$"*#&(+!#&("#$!+!""'#)")('$%&!'$)**'#'%$#!%#$""!)!$'$"$(()*"*&##$(')%*$&$#'$%+$!"!**&+#'$'%'##)''($))+$
@r3095
TNCGNANNGNNNANNNNTTNNNCNACANNCNNGTNGCNNNTNNNANANTTNGNCAANNACNNNCCGNN
+
#$!!#"!$!$#!""!!"$#"#!"#$#!!!!!!!$!##!!!$"!""#"!!##""$"!$"#!"$"#$"##
@r3096
NACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGC
+
%=5E2H3)00C#)H37:)?>?/D408H39)&-*"5.%%/*B67-#6?/(2$<7(>#F(A;<CH7EB7";1!>=$>)>6-477C?9:2A#>/)A(7.71
@r3097
GTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTT
+
&1)=A'>!(F;19H!&;&:@66"@,.-@D4'629@0"4>:7=!7#=!;E92&
@r3098
GTGAATGGTGTCACGCCGCCAGCGGTCCAGAACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGG
+
1BH-F=E:@46D+!G3+C0(4C'53@29@#00*@"509=0D03!>@#(-;2;$;).G19CGH,B2#@%=&$"0+4H;#G&FBC;'<2
@r3099
ATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGC
+
(35-B0A?3E'82*;H0,D&7#$74&4/4**/,F&,F@D&E&+9,0(F+2+FHG$(F.1+;6,(B;>0&3@#0.C&F>,@@H+#2!F
@r3100
CAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGC
+
<8<.94##2/;B$:.<.5);2:%7)A?@(=0%;D5/(C%-%660@9#$?HF4D+HD17G38"&?.H0&9<0=5;<;.4.B7*'CB.?%:?5%%(#%B!7:")!#9@62=AG3H6'C3<9(5AFAAFD,+;&78
@r3101
GCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCNTTAACCCCTGAACTGTTGGTTAATACGCTTGAGGGNGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTT
+
7,5A<<?""&)G60B-H("4575!?9E8?A33C0#++$B=*4$6)#;6;;#6+E0#(0'2<9,1)%)4#>D.!=2D+@H(!B4:++G)HE<%,7?AF7870&F1B/!F>#4*C0"F'A82%%?C*@8=H#)8@&E;3F88>H;D?4<4;$G/69$7#-?=@;%?.1,125H!82C>GE")E*C'8&H!*=E*C&?A@<9-?6-'5D;>&B<""CH=6(=!G-35.;,3#47%*FE4)0+B2DA9,->219*;/!!H$*=
@r3102
TCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCC
+
,00:*($>>",'<"%%?B%2;1!%)=(B-1$0/909HF',/B.;,CD#"*0*85-@0(#?.-(24G51%
@r3103
GTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAA
+
&1'A8F8735%6C*H-=+*3,,%$>?)3)%92#06A@)B;-,76&A/9!>9/CEB0E@3?9*;!)-*"-2466+<1"?:'E;4HD
@r3104
CGCTGAATACACGGGCGAAGAGCTGGACCGCGATACCTGGCAGGCGGAGCTGCAT
+
E9&<+D++/:A+%880DC>?8<%C@//!@"6876FDA674?A8;@0<)FB$,7>?
@r3105
AGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGC
+
C?/8456$'C'F)&&;=54..1=**!3-"@=33BD1.4-9?C<:
@r3106
CACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACC
+
8AGD)8B(48:'4=@8..?#=75..9(G6F#<#5@A0';A'-92=A(/D'.@7"/222/>14091GDG-F)A7?;"F>8
@r3107
GGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCT
+
3=$?&:)?4.3$#0E&0G&F"!;9;770">=@@2&:'F24%C+@B@
@r3108
AAANCNNTNCGTAGCGAGTTCAGATAAAATNAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCA
+
)('$!$%$*)(*$('&(+"#!#&%"''"*)&+(#$#&$&$$#"%!(!'%#)*%*'%""+)"$*'&$$"*))#%"*%)
@r3109
GCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGNTAACCCGGACGTGCTGACGTCCCGCCCGGCAATGCGTACCTGATACCAGCCGTCGCTCAGTTTCTGA
+
1G1>5)<.*@*1!5>.:A@"(-&A@90'+.&B8!A#%CC*,'-3$'EE2(DH!;81)1+GF?6(2*H4++6(=24%/(G;)!D!;H&/0CC6*/F9#$6=1B
@r3110
CGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTTGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGNTGCTTATGCTCTATAAAGTAGGCATAAACACCCNGCAGCATTTTGGAATAACCGACACGGG
+
*+AH9CH%"3!.0@H9@F#3'=AH;$5!'=,BE"H0=01F=/9)32'-->"DA5(2)5CH'%$=&H.):5-5?G#22#21F4/DF2);6$D2.<-'-3>FG$B2"0G!69A9,%5177%524.&$1B-1?/D:D1&F'D*%"6,%4GC0!9+
@r3111
CCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGAT
+
2""0&,DE5")64:256>G:4);FHH/:#A(5C$.8)#<*=2@
@r3112
TCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGC
+
EC"*9:H('.ECE1A"0+&%!2:GD=-7-'93&7*/64):A+$G)7'G-*3&:D*&&C;9>10HF(@<@8B0!%@CHG.903%
@r3113
CAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAANAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAG
+
?')&@CF),<">.;*+!H84*@&'&/;A9F4%:)44$G26G4)H%);#'5<E%)7A-2"C;612'*4'(<$(%%F@7;.9B1FB%7#2$6<#AC:-7G)B=$&G$11@&'
@r3114
GCTCAATTGTTATTAGCTATGCGCCCACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATNGCATGGGATCATTGGGTAC
+
,(G7H(&',?E*$D55@DB/+?@6!%G.=74A0DG+(9-F))(&HEA@(9E163-8*;$>5164F,-CF+!-..:95./!E1CG+9F?9=B4(5</&/.B+?9G'>=;<B8FBD?"8-7-+G$,4GH06
@r3115
GCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAA
+
>!*4<&+@;%<A":=CEG0/D1;D3GE#5G5H)1A6>@2D615$"2>/4C815!G&;#0-31B.4+367@(C
@r3116
TCCGTCAGTACGCCAGTCGCCACTGTCGGAGCCTTCATAAGCAATATCAACAATGACNGACGCTGCCGG
+
!D4#D#=:4.)6&,&<<1B-=HH:00$(4<H65H;)7=+8F'/4"3H#,+1;:-0B>%E2G1$,":$<.
@r3117
GCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACC
+
D.-?=@";?F(34C./)672B@$**15,&7DC:4/A+)*><HH/>
@r3118
CTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGNGGATCTGATTCGTGTAAAAAATATGCTTAA
+
B;"(4D2#-$C.F#C"=,%".'H2#8E63GE>H5?-!:-768,B986?3C6&;;<@8D-4/)-!59:=>84/6;A3138@?6("<"2'74=6<3!9HG!(=:*5#<!98E'40/:#6FGC*34HAA39DF1,E5E:8$20/#")=$+8*EB177$&(;:79G14C5*,47(A%<B%%!#=H'8("/-&1)!!18<"=G?15)H#$/3@:CB@!):45%B*=B2%D5.6(;D70.9-),(.'4$E@#14HHD@%)=;"D1*"1E16'75.9C0=6$*<06B2F
@r3119
AAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGNGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATNTTCTATCTTG
+
0&8@'"1+)A7</:85-'';0+!0H'4@D6D-=,"9''=67--95@=-?@5B(&?6&,;;5C7$%6F>G?D>8E'$"**.,B=>"<*%B6E>:(1=@CE,77=%&'G>:%=56>+2)<&1?*2G,.+@94.F+D-9=0(F=@$!F.<>53<82G%D=B.AG8D<68B71(H;&16<8<
@r3120
GATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCAATTTCGTCTACTGCTTCCTGC
+
(<@!!8C55(@,B.%7;/(632!F.)(:%A)D?00!?8'C=.DF?31:+/,--%(=B>6H!4!F46+GE91&?
@r3121
GATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGNAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTTGTCGC
+
<$($B(G<1":;'439>FC9@3!;F/A1'60,6'>/7?#5+"4>"6?:%,)B/GBB&;8D,288@,0$+)"60:!>9ECA(G2&?E@/CEE(A8'FC)"<=4089$D2AB"%27+$F#!E"'7#E&(=H9-5+2*544D?.FFH)&4*&&:$$-D-0,+7+!-=60C)BBGD%H8375&A@&=-.0>E>98EG%&)1>,*=0(%E%9C#-<1%:.H7+8'(=..1!@H76#&F+
@r3122
CTCANTCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCANGGGTCCAGATCCCGGTCTTTTCGCGGATAT
+
(7D*63"#--G"?B4%1B!H!6$@3E8)*FE),,'EG*5+(82*A,<?4B12&=0H8C-";@9"<++<&$.C;"
@r3123
CTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATAAGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTC
+
$6'%H=)"/5D/.H52HCD93?.(+F"6/$"()(;@4%C+865*"'*;2,03"HG22A!%%A?0)9(+)3*$4:9911*$43:10('+:16-%
@r3124
NAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTCTCTACCAGTTTTAGACGCTCTTTAATATCTTCA
+
!E#C!!->H5+7>3/>7F%7-9<53$2#<<9251<(:C%=3'@F?D01$/>;ACGF0&=*FE%H0)3'93#A>$D'='(@")+5C?>%6.2%0;+@&/,<G6&,E
@r3125
TCTTCGTTTCTGGAATTGGGCAGAAGCAAANTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAACANTCGTAAATGGATTGCNCGGTTTTATNACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGAGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCC
+
.#71/.9B1%.?H'+((!5%!&%*39H4&'A#0*/,347=&F)"DE50$DF09C0AB4+%=87D-,5/C:-;/(0$-34+,(64:H&22,3$8C(8'FE.*C!70&01;),B#E64E)+.(%%'@!1.D3D:+C?A'(#A-B!0#*@/7@+G.9"B*5@#8049H5)7C6-H$*F8<*@;,+$-D9+@H1@0A.@$+A$'/+>&&!,+9F9!)%F=-4+(,1A/F2#>H,G0/B,D8-G&
@r3126
GCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATA
+
3#8<8@7B6%%::;3((5&#B.3(=%((F!C?7'7(G5<*CDH&@1!2!
@r3127
TCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCANCGACGAACTGTTTCAAGGCTTCTTGGACGN
+
0C7'>DC<,)!38;8"?>HD,7,0A2)A93'7(>;"BB,(FDC0$6:#87@$F5".>H0?<C6G(3C!'>8,B;B2+)B$!
@r3128
GCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAG
+
2#@B<)"3;$8>5!G=A=BF3).,*%C>':>6H939=F%'?>CH0
@r3129
CGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCA
+
/<&4B2,9$;!58.B6?:D2-&8)E),#$9<>*C@</2A<*#:H<.1:DD2&75!#
@r3130
TNGTANNTATANCNAGAAAATGGNCTTTNTNCACCTGATGA
+
&!#))'")(*"#(!%%#%&$'((!*')%$&)!(%(()+*''
@r3131
GCTCAAATTGGAATNAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTNACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAAT
+
2+--21+:+3#2/2<$D*#581*95<CGH&-4%1C.&#<3+.E0D2+3D.:02;9.850(#$CE7G#:)DH/%B1;85GF.B0!A@'5.>-.')4959F3#%&27,E7A!!<6!%E&,025>!*+"FE&434=;E%"F69H>,6GAD
@r3132
ATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAG
+
C*B$@5,<:-6&5ED3<>;H3$2=&9D)"#09''2::288F@2=6)#?!36$;0E%&E"4@-)%,D=1??8(!+#0;+F/"",&#93-2!%A?6,6,%C'>@,<(7/*.:C7
@r3133
GCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTACTTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCNAGATGTTTGCGCAGAAGGTGTCG
+
B9<G<;G02+2C/6>&6D&99G#<'C55$>+5FC@3A1@?.EE&*A@!5B7G%7BE$!E8("'E<H"3HC@#>//0AB(<:6<%6(:#%<-D5.<&3$D=A=E@-G0:D30)DH87<--.4/<HBCG0A6"0A'**3@:*0*3-G1)E<FD&).6>)D%C8?H"..2B<&4<3*(@'45<>+E/;3/C8929)"!#;139,0!*6,%9B:&"0<+42G7!C1DG=93F#;,A7$4(C,H#2-A&F819)&4'8H/,:D7E+"$C3/-GG-:'"")9
@r3134
GACTGCNACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGA
+
3%28$?HE40%"5BC0G+>!;-.7@03&9",F"@)-004.A63(;<C*=%*85&4:A@@A#8H15@21A9"FH'-@/5-A4F1G/@;$G()#)4'0:E>4/#2!
@r3135
AGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACAT
+
99)%(679$)F6(C(*(.-09,)(6:H89H1%!&+;@45H!1&D))=$8A8C,)B8A>3:5+)0$8>FA-930)H*C8171@H+824728*+353-B$4+!1<240.=CG'&8;)#1$/>E0,,*!,&*&=).0GF%(C-HG;6A7;&C9D4
@r3136
CATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAG
+
B!:?F=DAG/-.@(1=8D74F!;<5D=!6<0H%H7C>F!4'*EG?-H=)1G!,!?3:-,&<6<$4F5(B-H&=$BDG=;-G%+@0<>'=)>,
@r3137
GTCTAATGAAGACAAATNCCCATTCTGCAATGTGCGAGAAATGAC
+
)&B2!0!EE%DD6%3GFDA+'3#:<D>B/F7<D-7>"2578$)E0
@r3138
GCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCANAGAAGCGGGCGGAACGGTC
+
2D?!+2;!7843<E.>%7;>*;->4C@@&:8"FC'<""%&<F%G:)'+)G,&19;29EG0;DAEG(!739<-A'(58E6$F
@r3139
TCGCCGTCGCCGCAGNAAATTGCGGCGTGATTCGGCACTGATGAAACAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAANGGCACCTGATACAGCCCCGTCACCTCCAGATTATCCAG
+
5!:C4-#?G=&G$0<06#8F-!,)D?9DE&"$32)A@B)<'"/"&&/<'-@53?>=->;B$6#?#4>7,<(7<9*8:5%D>?D4DGF&,--3D14"33<+9H&D;9$D%<A#:7G<)H?G:F4+<>$D
@r3140
ATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTC
+
G@-7>2A>0EHB;34-#H22E=C=@!'G5)2-/(3<;:C"H4G*-A3B-8+,!">2
@r3141
TCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCC
+
+:;#:/@C9(81BC+6..B035)7-$&05065!G1G5B4!G@<!B#::"3!.+**B7%!9&%2E:'F>
@r3142
NCTGCGGTCAGGTGCTGCACCGCTGGTGGCGTGACACCATTCACCGTGCCACTC
+
*6#6=>?1!<&9:$1/3;=,)@H1$'B/!%H-:E.2:E;FBDA#&;*::/'+</
@r3143
ANNGCNCCTANAAGATCGCCTNACTGTNTCGTGNNCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCAC
+
%&(%"""")#!*&*"(%%($#&&#"!%!(%&#(#%*&+&&!"+$!)+*(&'%(+*$()"*"'+"!!##')!+$+$!)!)(&"&&%((!&%
@r3144
TGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACNCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGNT
+
)/G+:-#&@$;''&5.(<.-&@F#BDF-43@?+G2A'+C0@5?.>8'G%A$,$.A#/!?7,%,+=G4/G&D#/D;8;GC"D69*,E1B"8+0<$+B$7H*9-B)G>!=%C)+%8;C89A*8'?+9<-6.@6-+,.5!&&E9F#&3($&67H-D:2339D)+?"0'69@7/-C"G-F!2=E<8B+<F/#FF&-;.'$
@r3145
GCTNAGAACNGNCCNCNAANGCAGTTCAGGTCGTTGGCAAGCGCCCATACCGNTTTTATGTCACGCACACGGGCG
+
)""'$!&!($%&&)!"$)!#')*+%!&#')$!!$"%($!*+*+++"!&)$&*#(')("%&+#&+*!)#%**)(($
@r3146
CAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAA
+
8.,$HC;<+-;4$BB#,50)F7$E-0-1?H1>'9F;6*&F-0A
@r3147
AGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATNTAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAA
+
6-H(<&#0H;06,:>$,"%782,/)907E/5EB)!-*96&7*+>B$#+2&!E6(3>-!+*2(9!HD+A=>3-0:99/?@+FH"=6:*47H91=#<
@r3148
TTTTTGTCTGTNCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATANGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATT
+
,<GG3.@E!.+D7(=!3HE3G226/*1>$A$B13&02<(</F$>B.#3;-77#F>=.B"(G;$8.5CA;:@2;"?3?5.=5&F':28G06*!!.*717)A2D+$&G>A=9*881G?36(A/-*<-H
@r3149
GCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGT
+
5.!+'@3-#C#D8&90!52H6//(8H/+C75"(%0%A"H'$2&$0421&)
@r3150
ATCCCTTTGACGAATACGAGTTTGGAAAGCCTGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGN
+
-D,8(459#!(,,,69:18&H%0%F<#E0/""/1"=F,1H$"/)B'$DB9'$G'8CB13&941>)9E'30E(2$+,C<,=?4/'?%-:ED,<,?+"E150)"?*?C%'02+B
@r3151
CGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATG
+
7:;<C!!A38$B/D76/,02E>;;""!)5@>E5<H@$C8:+#?1@)?(D8:7/&1056$6C388,?#+B>@(47F7#4HH(.')D2$28449;D1664."94%(-F+7<GB%2HA';#E</@:1#G*A)>@>,3:9/&D;*B:)C5.:@7@@F#9D9>"4$B28(<)1"
@r3152
GGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGC
+
9A,/-%/&#3*$'.0H9H50DA?!!4EDBH$A%:ECD49>?F(;F.90.*9')F!3'9%*A?;A>8?
@r3153
TGCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAA
+
BF7/!<D4#E;#D+B:*AE$AB"2'+E$,5,=:6=7%8>.>=
@r3154
CCTCGCATATCAGGAAGCACACCCGATGGATACGCGACANCAAGTTTTGGGNAGGCTGATTTGTCAAACGCCTGCCCCTGCAT
+
537@67*:G@>2BF&@BE;>FB31+3>-"GF8FD/H!E&;A)-,-=9"B5,D3>A;)?#(598)E<B4EGDF%6=*H:9??%"
@r3155
ANCCTGATTGCAANATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATNTGCATCATCGTCTGCCTGTCATG
+
*"+*"+'"&!*&))&"")&&"+)$$!$&$#*+#)#"&!+#(#+##&(($'(#*)++))*!+''$%(#))$!!&+%#+)'%&%$%)&!'##&!"#+#+)*+#"!$!!#*"#+
@r3156
CAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTG
+
2<+B>&76#2#D@+*#)0&1F!5788.E9A%--?:/*C.10@7>>+/)$G?.-E)?G%61=4GD.1HG0A1C=56H"-2?6?#2FB?C;-D)2/03G9&CA#7)3A
@r3157
CGTANAGGNCNNACATNGNTCTNANNNTGTNNTNTTTNNNTANNNTTTTGANNCCGNTNGNNCGNNCNCCNGNGN
+
#"$""#""""!$#"""$""$#!!#!!!!!!"$$$$"##"""!!#$"!"!$#!"#$"!"##!!!"$!!#!$$$!#!
@r3158
CAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAAT
+
C6'$7H'"%H*7-&1<<3AC1H,-+5B$7:B.#"8=&*%6G;*=%H;@*!)!%4;:"=%@+H85&>-;:;C67?BG3:09:(F(DC7!5?*#4@#62*%B8C.9*BG0"3B<7828#,E%F",?<&=
@r3159
TATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACT
+
#0'2#=D0@>(F+GCBF&/*@-*E<&%5>306)>2)'.;87<4#?H#8=27;A<$#>4!:?-&.=H=/
@r3160
TNCATCAGTTCCTCTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTG
+
!#''/$H)*653<5*;<+D(F1BGC94E%!A+C6A:+FG/6A=2F0;H-+022/.,H)&7*FAG4;")<E=G9
@r3161
GGGANATNCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTT
+
#)&&!+(!*#"%')+%)$'+''*&!$((+($%##&%!**#%+!#'!'!&$#)'+&%"&+#)'$#!(('
@r3162
TATTGTTGACATGCNAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTT
+
4(?07AH1F=C<E+@$6=1,?="F,14F::;44.*&A/E(<#7F*=!.<.#@H+)+327-4&5A21A><3F4=CA?82&9"'=$CD>&6=39(+':!.G;H-"$@56*?&+,
@r3163
TGGAAATGATGGNGGCGAAAGCAGAAGCAGATGAGAGAAACGAGGTATGACAACAACGGTATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATCCTGAAATCAAAANAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTNAAGAAGCACCGCGAAA
+
*?D-H!CE@5E-#-0)&7A$EG$0=%,8<7G07:<@=A@;C676&81<B@60?,='C/:D9*3)7A1#(3+3"A:5,;&G?A6+'3>+&HC)5&AGEB.5360'?135@,?!.(7AC0!'2$.D5-0&'3-+$7A=37*>&=C6+<:'C;F8'FC$37E>;>#E!$DB"@+='-7>'AC+<E@7?0%H>3=E5H:?&*"1:>+)/F0:%"F5;;CH1-#68?##,@%<?#!400.(<9=/2@>)-F-1$855'G'1<9-4:
@r3164
GNANCTCNGCNGGAGATACNNGCTTCNCGCNNGGGTNGATGCGCGGAGAG
+
$!$##'$"#&#'$#$"$!($$(*)*)#'"$!'*)&&"*(+!'()"+%!+*
@r3165
AGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATT
+
5E(5?.67?7$4DG";9@3/+(@B'$F!2,49@0/3,$A7CB#20;-G59B)0A%'@+56"D8
@r3166
TCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTNTCATTGATGATGCGGGACCAGCCATCAACGCCCACC
+
**)&*'+))!'+$(%)*&**"&")))#(*)&"#%%$''''&((+$'%!'$'$!"*$$!!)'!)(+)#(*$(+!)('&%%(((("%!)"%"$))%)
@r3167
TCGCCGCATCGACCTTCGTGTGAAAACGNGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGNGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGACGCCGGGGCCAAGTCAGGAGGCGTATTCCAGATTGNCCTGGGGGCTGCCGCCATTGCCG
+
:&!A*4*BB4>.4=#%.F#3;9;1=F3G-A:2&:08$)=1B%H&=C-%--=!%%A2B:*&;:G>E@>2;'-3CG%#(>H)32;B%03B(4!3#/7<,%D@5H/$F0C0>C='%.!9-G+:,@)2(&?FE>F3*2>2B(;H@BA<,/=1C"H5:%&)AE5!.7&.@/<4'-8=>&%C0'A7A-:31+%F6-1@B;6=2C"4=7EBG<0,8)>!:(DBD/B&$42:29H@4$*@$6-,?<8D&-#0/?A:'20)H6!DEFE7
@r3168
GCTGACTGACCNGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAANAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGNTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAG
+
#)/0(D/A-:B(@1!:D=319HEF5=-?($FE"!@!=>/'ACA=<F71H@96>0)1'((?#"H<.)&8%E5B+!9/G56,-06G.//"&9B;2B8+1H?G-&@074FG<#32*1;;>?64-50H9,"8:%;.76><)'534BH;)%)-2.6*92D0*G+7?/>=78B3@E347&<"8'-G,=,E&1"F%;F!2*'"A%>60D23CG?$9+H=2,A-*EH(@21.54F/(24FG56F6)(,5AH.'HG""+.C/*3E-)5.5<>A;'C7CE3'<)@FG&H6G5@(&AE%83:D8-@*)>$#-&D<G(%>"C8DEC&@<4"H83--(;A:,97"!:6)$E:7-AC#%4%.4*BB;5E/*E?,AA-;1-<>)H/==4G<<@28!1'&$2.E*C5/+/?*0;FA7&'3"=)8+)61<
@r3169
GGGGNCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATCAAGCCATGATTCAGTGTGCCCGTCTGGC
+
:+&;/;$E18F80%)#-,**(;#6@,77)$A")5B,C(>'D3<;3)46'CF'=<CC.92',&<87E3!1
@r3170
CNNACCNGGANNAATNTNTTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTA
+
("%(%%!)*&'!)%&"!$+###)!'$+*#+))##+##%'#')$$)'"+$'+'%%)'"+!+'%*#)'$%&&&"%)"""*!
@r3171
NTCNCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTG
+
&;"14G>'17D/,3;"19<9&3@C0<-1(*G7"E!<C3*BG73)?79,C78"&BG+'2(03+7G32'+2EDH'3/.&H1>99D6!%-2E!EC%*)#*537<">9'#F-&
@r3172
CTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCNGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGNTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCC
+
@1C)%,$/A;;+B9%1GH)1(H;*69(",)%=#'1A-!<;2%5!)0$2'1@#,+44!E2F?=G;+30&35E<0&<<"HF#$6C*<>?4-6?E>%=83;H3('(24B3/D?H5B5F.)<86*.1%#F4=A!(2&"(C+G70H18(>#?>-$-!<F-<7%>?!C(!EEH1&1EG3<,="G(""/162'1A(>:?;;)#@>.$@=!="6>:-A.7.0:$EEDG(1)G=<FC"5024/=$'@A49?$7#3&$<F'+3;FC6=)*,-:)>*C56,,(.2:9+7<:?$?G"A)/334.0#+H8A/2B<BC??-D(;B
@r3173
TACGACAAAGAAATTCTGGCTAAAGCNCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCANGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAANACGGGATCGTGAAAGAAA
+
11;)=88CDC&$3!.9%B6):B%.H'31CD#5@)$>5*='G21!C,/B*(9/@$:3@..7C0;6G&'2>.%C'042C4+6(.2:&;$97&%CEC:-C0>8AG:C(+B*F=B4#2;<>@<%!=A!+.D5!5&"!%4A)AEDACCG(-&D$$#;D<C2F+A451+.?36/BG)&*/5E;."!!,"0B//18%%<>,49>H205+)486EC$22
@r3174
CGTCGAACTATAACCNGCAGACGCGGCAATACAGCGGTATCTG
+
8F??*=A%)+6(4(<+''+3;G)<)A8!25%$B*GGG0B>@.6
@r3175
ACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTT
+
*+&+&($)+(+!''#+$)$+(++*'"&""'""(&#$$*#)*$!"&'
@r3176
CTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCG
+
&F%68EG<&;C5=,5G.;??.-'!E>35'3#@1(>0>$(90BA-@#0G50)<+$#,,9-E
@r3177
CGGACGACGGAAACCACATACCGCTTCACGCAANTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTC
+
.@.-F#.8&E"C"@;(G0&=-??$H0?(!/:+:A*/*,75?80=*3GD5H$A4)0=7@!'9!$C079*%92/<3!B*349@<."56,6G)E">?>GC5=51+?3
@r3178
CGGTACNGAAGCTCCTTTGGCGTTTNCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGT
+
&*%$&*#()*#)&"++("!)'#%'"+(!$!"(+&($#*!)!*++#!((#$!($'(*)&!!)#$*+!##"!&#&*"&!%'++(&&#!'%&&&&*&#+('$)*)$(#(*&
@r3179
TTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCNGGCTGATGGACGCAATCTGAGCCTC
+
*6C:?4)D@>?#81#916DC+%E:5G'7BF/!0;B8?'-9:+77D=C71G-,1%+6,1%7#=4AD#;3BC!*A"HD7;%B38;,4D'-13DC
@r3180
CAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAANTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATGAGC
+
E/$;8*D%)*%0A>*(;)<95;3#'A1??'7,;9=D-@"G-G<"<;,8>53=:9:@3?*E<"!H?1+*<23>G7?-4<62>B!4-E9):4=*144(,=E$6@.*@A("*0,/"
@r3181
TCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGC
+
.?55!1A(E67(B;>*=1*B3G)<G-=<1&7116=+<,?=940%4G+H#AG393E<$G!+31+:>/@=**%+DFG>G.B)@+GC@(H'D4012G8%
@r3182
ACGAACCGNNGNNCNTTCNAGNATANTNCGTGTCTGCGGCTCTACCATATCNCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACT
+
"(*'!%'%!%%'!)!&(#!")"'')!(!%%%#+('%+#+&($)'#%&%#(+)$'!%&($%")"'*+$((&'&($"$+%$&"$*#+&(*#
@r3183
ACCCAATGATCCCATACCATGGGAGTTGTTCCGNTGTGGGGAAAGTTATCGCTNGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGNTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAAT
+
$(+!("+(&$"%&"($(!*%$$+($"$"$"()+&$**('&"''+%()'!)(&$%+(&#*+#%(+&&*!#"")()!*)+(&"*"('()'"")*)!''+*)))'!&(%**$(!$#+*!&"&'+)+#$++((&#)"(+''&)'+####&+&!+)&$
@r3184
NATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCANGTGACGCGTCAC
+
$05:4.(2=>$+//!F65E:&<&'-#E9#D(A-$/<'(0(2#4%2"0?9=%D:;%5F1A4E=E'2HG?)
@r3185
GCGNNGANGNTCNCNAATNNGGTGCAGCNGCTCGCCGTNGCAGCAGTAAATTGCGGCGTGATTCGGC
+
*&%#$)#$*&'&$&%'''""*'*'!)(+'#!(+)%"$%$#$&+%)'*%&+'%)'$#(++#""+!("'
@r3186
TTTCCCGATTAAAAAATNTGTCAGATCGGCGGCCCGAAAACAGTT
+
./1!0"3@4).C=B!D:5.!6*-!2$H<6A#9.;:+2@B<"/#,#
@r3187
TTCTGTCTGATTTCCGNATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCT
+
6CD1*27-"BF,)HA!!!1#590G)DE.2=?$-,-!*01D#F5:.0A')%+;D29?52"'12AEE"#)-E@<$14>'*,>809@"C0)$+'4,!1B%G1F=(-1G37C6;3H#<
@r3188
TAGTTTTNNGGNGTGNATTGCNANNATGNNCNNTNNTTGAGN
+
$"$"$#""!$$"""##"!#$!"!!!$#"$#"!"!#!$$"!!#
@r3189
GCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCTCACCGTAAACGTA
+
H%9#+-5/-'/E/H=G79%7C(?5>,F$;9:*7A$7/0CA/<")1%=H=A,"61=1""
@r3190
GTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGT
+
4&!#F$-!:9.16=E.4D=7*G#+G<"421.9/$@:)<H05/0C<?)!9)G:;7@+@)6/A/%<'F592%54.(E,:%>)++/4*?($B.=)3/%#$@)"FF%BC7*;D04D-2-;.88(/
@r3191
CCCTGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCNGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCA
+
?1,$(%46?9:+4.1,2A44;<G:>@3AH$B&3)=2644-92>)EC5#F+0@=D=AD/@8#GF/)<9)A.F9?-&59;#*&8-(F3*;,;0",@$4.!E:($!1HA@4#2'E*6$B"F,.8F7BC'>$/*#G'/(,8A'8D;(",BH;1017&@,D=;7#9->**9H0C78$;59&3!C$(F&@%)@BB=?.)G!+C(176B!<./*?1.&:2,.DE"?59:E&G@<>D!DE?3
@r3192
GTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATNCCGAAACCGTTATGCAGGCTCTAACTA
+
0$#7@=;D+@.5G1@(F9&1:5+/2)@HCC)C:*(831H1C@@3=G<FB:"",161C"-A'3$,G&E@G>81AC@E)?#752)CAB:E/%8!?.!1A8C>45<D?+3-//<9616F8#%@-!;&17EG9#!4..#(+C(B8)$(9'+79@"4B$&
@r3193
TNTGGACACNGGCANGGCAGTTCCGGCTGTCGCCGGTATAGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGG
+
!*$*!)()$#'"('#&+%(&%#&!&)#"')$**#"#')&&"**)('+'+'+$"'*)!%%)%'("%!#!(*+)*'%+"'!')#"*"+$"&#*("(())%)'$"&&*'+("%!&%('(#!%)
@r3194
NCANCNGNCTNCGGAAAGCCGGTNGCCAGCATGCCACGNAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGNTTCACACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGA
+
'()"&$!&)'!+&"!(($)'"!!+"$)!'"!#+!!!')'$+"%!$'+%!+''"$)&)****''!&"%(%&!#%*+*&!)'))!!*)%(&*'!!'!"*'*"&#*"+&!**!+&#$%!&!)$''#)&&!%)&!(*%*+%#&#$!%"&!"'"%$($%+')"+#&&"%&'
@r3195
AGTGCTCCCAACATTCGCTTATGCGGATTATTGNCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTT
+
$12&)$F?9GA$E"5+)$'9D2!-CF/-A/,'74'"C)D+<:E88>$=,6%1-1C'55&:0-#$;8-(5$*=+<D;2.1BE:32826GB=*D-1
@r3196
CCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATANTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGATTTTACCAATGGCTCAGGTNGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATAGTGTTAGAAAACGATAACNCCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTNCAGCAATACAGGGA
+
2<2*?..2'>6-8@A9.FE$*>BG#B/-":G3&B-.2!*"G/-A>#:5,'1,81(;97=&@#A(-<+$6,;=+#D%BD-%C7<8$,8+*!#*F$B#9B4G.%9GC:C<E8<-"9/":EB9#C86$#55)D1B8F,,B%1E=.-H,%4"$96$1(F45F'G2/3/2+0,!CCF)<5./$9G$*G!3?<'=4BH6%6'),%.=,<)?=7/!<$@6%9,8%54>+30#.3"D6!;#*.2-@21/4;(5()+98*ED=@(5#-B)=2>ED)%&'@C>"H33B"C:#0((HF/0#E;6.D3*39:@*2F.<8@%:FBDB&9,"78?/@77EE7F2CF42!838?89<C.F'-/&&64H);.17D900,5;?(,+DC&/#4;-@D0H!0+'8*,=-6-*46-%)%.54:*G>!*%+?'+'+77'2?,G#9!=7;'=)D6<=#$>;@$/=,;D5
@r3197
ATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTG
+
:$?*;==*,"G-4C'3!('.>#DA%G'<19F4")")+8CHF$F%*1#;$C>:+3+54+D1$+&<,%F(+=0'"#E)67A%:)1#9/6=,#+/9$BB%AF&70?D)H"<10=C+;D5
@r3198
ANANTACTGTGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCNTGGNGTTTACATAGTAATAANTCCTTACGATATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCCTTTTCAGCTCATAGAGANGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCA
+
##"&&&&$"'+")&%&+'*"($")#()!!#$#)!$))$$"()!%!)"!&%!&(%$+)$)#)!*'#+"'%)+(%')'++(+#"+'#"&$)($#(+')&!')!)(!%#&%"+()$&('!&*""&%!*+$*+#")!!((+("%%%%)&#*(%&"+*)(*%*%*%*!($*($(%!(++!+))''!"%%())"*&%+&''(!!)*!#%(%&'$#)%'()"(!(#(+!%+%%((&$$!")&"$#%#*#&*(&(*!!%%')%(")$(&)"#++&+"+("'%)#"('+'+$"
@r3199
GACTGGTCGGAGTACTGGCCGATGACATACAGCGCNCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGC
+
?77?)>#!1@"C$B?/*03B?1/(80!$B81:B'%#/34%<-'@4#=A6G&G:C0').1"!9>CCAH,-=1F?B55,=!#HD
@r3200
TGGTTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTNCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACAT
+
%$!*+($!$""&"#&#)$$(*'#(!**"(*&"$%+%"$!($(+#$$!')!)+&'%"')##!"+!("$#**%'&#&+)#+!+&+!+++$)"!!)+())'(($!&"*%(&
@r3201
TTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTG
+
?E%%===B?@5+6&5(/&2C2'0E7AHCF=;+G6%!C%@FC!,0B
@r3202
GCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCTATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGA
+
-=+>0%HACB049.-G;12,<;='9-=$A268F)@851.5,,@&@/">(3$;:<D3!:AH8CE#=)#$ECH?!:#@:62?4)@@2&!;#&B*3=<=1<+C)(E%("F9$)+B+(+7F)!07C-F,':"C,%#-;5!7.-3?D3BD#>!%B+$4C(9%%*H47
@r3203
AAGTTANGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCAGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCT
+
D**&E.,C"<'.G+64'BC#?G/.E:=7%C&F8</"0G8D()B5,#$#=7=6:0FC3;DA.1$0HE2:,#B0%6;B@&($F3?+65++=9!?D-D
@r3204
CGCAGACACGTCGTATGCANGNACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTNCGGGTGTTGAATGATT
+
:@G-'=:6=;1'/'>;8+@*7+4(E*/8E%?%=@&;<:7>0'?$(G'7#H/=%G-@0//*8-'37)?D?%)'4
@r3205
TGCCATGTGGGCTGTCAAAATTGAGCAGACCGAAGACGGCAAACATTATGTCGCGGGTATT
+
@#):F$7BG/E>;6+E(*36&)+B'G1A2;+64&9E0G0&463?'?6907./*H"C:>(&3
@r3206
TNTCNCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCT
+
(")&+)$($')&%")($$(!%*!+"####''$+**&(()%%!)&'*%*'+
@r3207
TGCTTGTGAATATTGCGTTCATTAAATCGNAGTTGAGGNGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGACTCTTTCTC
+
$5E>C2ACH>C,.=@2>#CF'0<>,3>5F84/6#7FE6**6,G7/(00*."?-GD-'/%C*&#393C5H?6+4EE'/@%6.63%(7D)3%*59;AB'31"05&8(-'8-.!*=4:9%!/%"*B41+@F63
@r3208
TTGCTGCCTTGACGTNTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGT
+
??E0);GA3C:=;E>?H2&8H0AE(D06!A!64.3A3),EA*?060).376#4&>.0%&H>5C+*
@r3209
AATCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCNTTGTTCCCTGGTAGCAAGCCGGTAATACACCGNTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTAC
+
)$(@4$(>B(/%DA2-3:@8B1H5;?02<EE&2<+&@,=/8>7=82.EAHB2@%#,:BH6F8*"F:/+$?78>ED6$0$&C03"#1!<:E<7<<>!>.7(?#7!09-1G4H.:2=)>%:C7F:?2HH?<F"280)?9""$1@BF!E7+
@r3210
ACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTG
+
=4#9%"E=:E%HH.*$734(#'@;,<DD==%$"HB!6,<G<G6?!+-H0',88F0B/.!0D*EAH8F(4!97+?'D1E&#69(",,#2*-=$"!*HC!C87&9G$+H'1,7;4;)D&#90(-BGB4D*0*@F(=);/F@&)9,02#0(>'B22#:A<0;>1216H$CEBG)4HB"'5(E;%>E'#4+"74%%-(720D!<?/5D"1DF=&4>C3@-#%*+-FC5GG#F('2(&FHC-#>2;1>G=2(%$56@C!&#*A.9390+"(C@$?"F-"!62$0
@r3211
AAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCNAAAGCACTGGCCTG
+
&49,<.<HB&9*?')?G<26((&8,88E,*4A%5B'6HB8,%,E6!;+H2/@D,'D@%0.6$@F6+-?&D#2-<1*3H?!B6A'=!$';D%(-@#!+@-=/:E/-73>D+HF44,'=@-:*F4,9?+B?>3"9@:6,"&,654FB9191A7:/=4'5,@:&-=39$E/E)">B:6)+1@@?>5@;G#.)?CE45'=3F$C,1(%$-?$A,E(<-=A@G=@"$7!)+(=D)*!89%*-A*!>96@B.@3;+"4@4!F5?(*<322**;?$5E
@r3212
GCGGGTGCTCANGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCNGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTACTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGT
+
:(D9<;<,G&0:'>5+#C,>?,-)F$"):$(7#32.6"4DED+H-92+*0FC&)"FE("D7>,F.<<EC8H'B*,'FH!6//4%E?)<!2F1>9#!=0-+,A+51B5.HG:(D@+G9EEE<9-'('AE,'@<'5-#DHC"/&!%*+;;!"(H1"-.::4!2<D659*'=.()).
@r3213
GATCACTATGCAAAAACAACTGGAAGGAACCCANAAGTATATT
+
E%;A+C%5:/$G4?:D368:@8:<H8FDC#G6?A11+)00F4$
@r3214
GTACAGCCAAAGNCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAAC
+
1@8E%=,A9=)F0B>".&8/1G"-3+GD8,.?-*6>8?%8;&%'3>*4D5F(=(?7*=!F/!/#"672
@r3215
GCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGNTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGG
+
("7;-H63<9D$%5*)('E+"41A4@?1$'.1E2D&1:(2FC<@"=0*?9C-25:.<-,?3"%G$(4)&6/C>781<C12$&BGCD/>$2D.<GA(%G46E,/C6)D'-"G+A6G@1<?@!-5;+>$,'B)G5!A,=1A9?>H(&0:8#H49<76;=:E"3%*,A852=)6(/!C1>#*B*<B!DE<36'5)&@24C#(BE*.01)H-$=/(?;12GG;-*
@r3216
NACGTCAGAAAAGAGAGCCTATACATCAATTAAAAGTGATGAAGAATGCACATCCCGCGTTCTTCCCTCCGAACAGGACGATATNGTAAATTTACTTAATTACGANGGCATNGCAGTAATTGAGTNGCAGTTTTACCACTTTCCTGACAGTGACAGACNGCGTGTTGGCTCTNTCACAGACTAAATA
+
"+$%$*$$#$(*+&&"#((++($'#%!")'"!"#"!('+#($($"%%*'!*!!#+!($#'(&#&*"&&%%"!+')#(')(++!&%#)&%!'#$%'&"$%*"%($'#$+$#!&)&'*%'*(+)'(((*$'*+(&'%!*%)&++%'"!'%"#"&+)!#"'$"&+!$*(!)&*"'%+)%'*(+)""#)#)
@r3217
NAATTAATGTTTGAATGTGATAACCGTCCNTTAAAAAAGTCGTTTCTGC
+
!F5@EA(=9/#?F%00"&!'"5'+,$5!+(?+B,!<9.3D(5587&<,$
@r3218
GCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCT
+
7@!E.37)HG8$BA.0EC$#+8+$@,5=7&&6&&E9<4B,?(-=B?A)68E(677>.'G2"=*$*;*892:-G36*+.0E*'6$C-
@r3219
NNGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATCATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAA
+
!*+*'#!'#'*&%#$&$"(&)'""#(&(!%$!)$(($*"%'+!)!$$%$)&%#$&&$&'+&())"&%""#!)()((!&"%*(%+#+#
@r3220
GGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGAT
+
2#(F<B0)$@3-?G5&'7.A,;+E3:@&/0;/1?G8DG0+1:9FH0&B#1#
@r3221
NNAANGGTCACNTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACG
+
#!(%')'($!%%+&#&&%(++%()+"%#&$'(!!!%#%*#)%%&!"#&)%$)++&*$&&"!)'+$#%+(%"'+!''))!"!+)(')%$&*+!+&%"#*&&
@r3222
TGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGNCAGCGACGAAGTATCACCGA
+
/8;#C6CC?9(6CB18?B9/<F<A/&(0(,*0F"34)36"#%=!/>>=+.B2/@E28/-;67A23@9',09)2'1*8A%+E'?:42B(HED9G!2FA<;<F6=&:C#*.+1,6+>>G+C%*-)-$F9,%8DF>.@H%&%C:'>#,A
@r3223
ACAGGTGCTGAAAGCGAGGCTTTTNGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTG
+
2C@15D4&9=HG0H<5/$#+E)+A:B*#A.2$G8A92-@<E/1B9*937%CA8"4-&F8DA
@r3224
TGTCAGCCTGNCGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGTGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGNCACCCCTC
+
:;)56%G3@=7C?GFA@7@<3;%:4!:4.:&.).6!"3C?=B:(GF/";>15?@)&@+@0H047%!/>/529A;70-4">G((48C090A@>!;F?1##69
@r3225
ATACANCCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACAC
+
!)/%,3:($30F9:.>'$<C%@6?(?B2-*<%"0,1+?A4/=)!E:;5FFE@
@r3226
TATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCNAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGNCCCGATCCCGTGG
+
5DBF2G+'$-CG=F6H/:)=;9A5H"#.B-;0)&7):/39',"H-?:'.FAF41,%BFF"(AA=02%(A?+FA5D"7EB9C)6D6.A1+0#?=###.E.(26+D!$'%=!9*HE!':E8%@F64C031EAEC2-0!7HD0%BC!>FF
@r3227
TCCACCGACCTNTGTCAGGTCGATTTCCCAGAGCACCAGGCTGGCCGACTGCTCCGCACGGGTGCATTNATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCAC
+
0/:1=8-2766400+)<57D!G(4A7,=#)!0EH"<*:3'52?:8F?;>77E9E/(;$)H/(HGA%.-"(A*,.2&8;<FC)B@BB$E>/CF:1-G5G.2CC4C+()!/:
@r3228
GCATTCGTCTCGGACGTTTTTGCCGCCCTGGCNGAATTTTCTGCCGCCGTTGCCGTGGAAGCTGCACGACAGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGNAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACCTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTNGAGGANTCTGCGGCTGCGGCNCTNTTTTCCGCTTCAGTGNCCTTTGCTGATGCCGCTTC
+
?:9(E,'H&=;&2.,0/!7%997"2+F1%<%90':3:G)C,BG9,?F:B5@G260!(>+("6D?1H<*G;%1>-6%=%72A+&!3+942=@@0#68&!3-3*@*B/1:!H,;#8??)#/E1@*;C8'>7H7=A.A/;D,D148=<&!@'+A@FE./>%7'"AE/#<FB6"D(89DH75#:)??):'#F(6)!6@?>&'9#*;,%4A'#;G5E(&GB,3$7:&92#@#-D57>4G/3C#F<3.9:9>/0:D:5AH)@6+8&.@6?("1#)(.=8%1@;C*3HE<+5809E))";9#:=:FB261!5:.A'DD-:)9&-/5&D"#
@r3229
CTNCCGCAGCCTCTGTNGCCTNNGTGNANGCCGTCGTCNCACTCNCNNCCNCNNCANTTTTTGCGTCTGCCGCNGCAGAGACGCTCCGTTCCGCTGCTGTTTCANATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGNCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTGTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCCTTCGTTTCTGA
+
!#"')$'&&*)%)*&$%')(&!%)#""%!("'#)!%!%$#($)$)#$#(%%&#"(!")#&#*%%"&(+)**+&"&*"&**"%%&%"**$)$$*)*#++('$"!))"$&'+&"++&*!)+#%+++%$*#()('%+!!+&%*"&(+!&!()*($**$('&(#+%))&!('&+$$%"+!(!%!#'$)'#&&'*'&(&)!()(*")**!*%("+'++#!#&)++($##'+&$+"!%""#$%$%((#(##)')%'''+$&)()'+$'&!$(+%!%%'#(("'*'!(+&*$((##&$##&%!$)+!(($!(%+&($+&!!'"#!*)("+$("++")*%&%#"*
@r3230
NANTCNACNCGCACGGTGCTAGGTATTCATACNTTGNTGTCANAGANTNAANGTANNANCAGNNNAAAGAAACC
+
%)$&(#$)$($*&)*)%**!*)!*#$(('(!&""(%'!)(#$'*$"%'!&%&)#(!!())$#'"#%++(#"!&+
@r3231
GGGCAATNGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGC
+
A5()?DHF68:A%@:4B*+.3/E:<$&27#%?'7HD0BC*0.0,!
@r3232
ATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTNCTGTTACGTCCGGCTTTCAGCTGAATGG
+
((CCE&#,%AF;51E"*@,/E'=HE6:<1<F;F.C.72=12&,@=/E0;H5DCBE.@6>@@)<A;C!-,034<8+C-".'>(H%G4C=2:G50"?
@r3233
CTCTGAATTGCAGCATCCGGTTTCACCACAGAANGGTCGTTTTNTGGCTGGTCNGAGGATTCGCCTAGAGAATTCTC
+
#".;%+B4GAH*C6E6;+GE4<E(=!7A-/:/B8F"64(:)<"A>!&2<1&:$/8#B$:)1@:H>*+"1&E9@1B#E
@r3234
GGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGANTATCCCTGCCAACCTGAGTCAGTTCA
+
3A?"BH=)2:$B5.'300-//8F.;G(-?)?/$".-3-923#:<@20*B/B:,::,-5+@0%C6-
@r3235
TTGATGCGAATGCCAGCGTCAGACATCATATGCACNTACTCACC
+
)<'+DAA..+15)AAA#4>$2F2=1"7936#B!#@H'2"D1!#<
@r3236
CGTCAGGCTGNTGATCCCANGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGG
+
28>&.<.;;,+)<B=#%/AC9%:)4E#@C0-378<#$29>!>'0F&37D+C2'@C=)$F'85-C#:@@6/G!)=,066;;13D6A-8,#B58.?G81>.#'57-($)21A)2@EH4B!9EB&$BF.+6*C4C9;&4820',.69=B<9G'*D.8:$%@="8,;&G8E#D36#-)-!"-G&3$!0F*7E,.+A&(FH++8"=(-+764
@r3237
AATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTNAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTC
+
8,G""?1G'C4D9-@"<7D;29G.E"5>6$5"'.*<F15%+<!$54#B2<F=B5CFG+'0AF.</-)E,52B!&;;@720,9E**,/10.5'?=!(#G:D-.?5C,GF;>*F="4G029?>7+23:2CG*".6:)-D30!$<$##)D3'0&=<G:#)!H<:+<5<7/>33FG79
@r3238
GCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCA
+
;*/#9H:*$:5B0:+1H*>B@)-/E>1EC<D0@(+.E97)+!C
@r3239
ANTACTNNCNTCNNGGCCCACGGAGNCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGNATGNGTTTGTGGTGAATNATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGC
+
)"($*)!%(&%%!$)+!&%++#%*+&&)&+)$+!$%)()"&%!'+&$)'$*!"##)((#%)*!"&$&(!&"#'#*!")&#(*#$!%##"&#!+(#(+#$#+)%&!&$(%'#&(&%+"'())#!%$$"""#'')%'$&'%#&()!+(%(%$#!)&!+#+!$
@r3240
NNNNGGACGTTCAAGCTCGCTCGACGCTTTCTTGTTCGTA
+
%%"!(&"$"&&"$+!#*!+$!*)"'&&((+%#%+"++"(*
@r3241
CATCCANTGCCTCGCTTGAATTGTCCACACCATTGATTTTTATCAANAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCNTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGG
+
*6BA,*7B.GB5C'+GG,!5;%$+B;CG@A5?/G='E:BH(@FF/#FA'-C!!0E<@%G:.=;"%0/+D/@)@!E-A#!&7#>$64*-2?0A-E>490;=/)#!H2:0181+E=?"09",!G#AE0!392!<DG3*+=F)>73E-=)-
@r3242
TGCCGGAGGTGTCCGCTTNGGCCCGGACGGGAATGAAGTTATCCCCGC
+
()9(3;D,D,(4$8",><#D8G13<'/G.)EFBEC3/*/.AC34!9$7
@r3243
CNTGTACCCNTTGNCNTCNAACNCNGNNAGAGNGNNNNNTAATGATGTCGATAGTTACTAACGGGTCTTGTTCAATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCAC
+
*!"*'&&'*#(&(#"%'#!'((#(%#!$(*)()%!$"!$)'+"""++*)+%!&&!&%*)##(*&!)*)!((&!)&$)!'"#)$)(#$&&!(%&(!#&"(%%)%*&(()%!')%'$&"(+#(&"##+""%##$%%%)'#'&$+#+)&*(&"+%'(%$(())(%"$%%+%"$!'&$)%$&)&$$!#!()'&()#)+(#($)#%"+#"(!''#!+&#+#+*)*!($(!$&)#+"$%*!!+#&(%!+
@r3244
AGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCANGTAATTGGAATTGATTCAAATAATAATCAAA
+
6G"#2#9((4<DG77.(C0871;C*&/;+.C%=)G),!./=&<";A0&?*#$6B'0*9-2D":G23F=GG&267"H#3/!5?$A(>1*#;C8>FE;)(9%%15#<6"'*AF-A8@E0FE$/%;4!"BA&0C%B??C2)6@1:)2"?9((
@r3245
GGGCAGCCACAGTCACTCATTGTCCGGTACANCCGTGAGTGCCGGNGCACA
+
@<)-/*/5375F0,F9$2-HH0@,F!37,!911H+,?)H)G=:F'D>$D9.
@r3246
TCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCA
+
A375:F,%/571)<G;%*@*2);&2C5BE(F@-6G0=?*:2!.:@F/?E.
@r3247
GAAAGACGGGAAAATCCTGCAGGCGGATTACAANACGCTGATG
+
?,9/:C>)$<>)%.#%!7H5<$.7C;%C!:&C784D*$99(=4
@r3248
CCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTNATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAAC
+
.=3!";?@$56;01/C>00D+C=,D$B@C%C/0"H)$?:.F95"$$,&$B.;27D*&&(E,.-<;*-*:3</#83!E0!!C),9#@=F2<#C-C(H>3>A2!$3$GE,-1<F$%!E8@%D9#/#"8.B?#/@*++EH#2"72D'D=:F3H1;/2B!%$*14H(B:&%;,8C:E2DAC?$9)..$07<7G9"9F##A8;7
@r3249
CTCNNTNAGANTAGCCATCACCAAAGCGCACCTTTCTNACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTGCAGCGGAAG
+
%%#!$(*)'%(&"&++!$("$'((*'(*+$)!+!*$+&!")+)!$'$)$*(!'#$'(""!)""*"&$")'+)&#)+!("$"&+$'"')(
@r3250
GGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATNTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAG
+
.D-/9D31-:4=$G7&4E7!,$2B0)D?%.5(19*7!C+=%2.3>#?=@!35.F@=EAFG,02*+."%05:-3;')?:73(76!0$48$E(B$E339B,$)4F?:=%$<!.H&'0&A(,>4!2/'%$%+G46&6+2?4?5.0%/,8+;G&&&/'E0*)F6)@=%-1!:E6*H%)018>:#E$+698-">#:"B#'74C-/-4%5F9$>1HH;D(-?2G,?&E*70D7B@<,<"C80*18B?'>2@.@6.%A*C!=86>3,3?4<H/.-=B=/,@-&C6<3E=(A#1DB5=0/+.$$-6?%.BF;3+-,-
@r3251
GTAATGACCTCAGAACTCCATCTGGATTTNTTCAGAACGCTCGGTTGCCGCCNGGCGTTTTTTATTGG
+
($+$!*#""+'($&!'"#)(&)*+")""%$**)$#*"$(''#'*%#("+"+"'(($&%+(#)(+!!"$
@r3252
CCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATGCTGGTGATCAAATNTGACAGTGCCGGGATATCGCTCATCACCGGAT
+
.!91;AG,:%2.)F016GB&:G:+B0=EB405G3:*?4:F)F<7(=(0E*-6%;7):,B>/"&BG/,$##H:A,#'-'8C1=890*B'!G
@r3253
TACTCCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCG
+
3073!:;"$+#?C-DBHEC$@B"3(FC-:*)(@6D0%E65'"=8'
@r3254
GGTCGACAGAATCCATGCCNACACGTTAAGCCAGCTTCCCAGCCAGCGTTGCGAGT
+
;HEF/5&1?>G%/>2H032H)!=<3951(<3*0);C6/B##A7B#-B-D&H&&-?3
@r3255
NTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACNCCATGCAATATGCCATTGCAGGGTGG
+
!GCC,G+3/*BC;'*#8;12%/5&%&)C(1#%?';5GB74$./*:?F@B.*$2E7;#%=,1&:?
@r3256
CTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCANGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTT
+
C)>%<6A8%C;+F%A=E@3+6,:'*D%C24.GB#/8+>4#,%&#=F25:#*A7G69+@1#>:G8D.70>/F-)%!41+<3A'4$3)+>B/9)*F5B)9*@#;H6CA54"5<+5+4;2&8
@r3257
GCCCGCATGTTCTAATACAGGTTGGTAACCAGCCAGTAGTGCG
+
7+"4(0!@-B."4B<H.BH'8(*7F/A04<?76?C5%0;AH.$
@r3258
AAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGNTGCGTCGTCTTGAACTGATGGTGGAAGAGGNGGCGAGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCG
+
+4BE4;&.="*D(664.#&2-:4"G=3)=D.7-@*3#3(9C&H80=5,96%7F<0?09G:ED24A4("EH$?D>/=D<.:)3D$7$%.:B=''=E7E")DG$;8B;-+!:9*FGE$32?99(*=F76"!4$-3?:D="*&3B24:BEF<0)/)F3</-;*""*>4=50@?>3+B<97G%0/+-0953;31>
@r3259
TGCAGATAAATGTTAGAAATAATTTCATTANTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCNACAGNTCAGT
+
1FH=6<3<@A9+*3E,&:F$-3%",@:1.6$#!.$=FC'<C-F2#='5(+'204%',$*%&BC<"=FB085C2AC56&F;F09<440!->:43
@r3260
GACGTTCCCATGTACCCGCGTNTCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACA
+
@$4@A&CCE;2=&4A:(08<)4E!*>E*(/E1"B;D+H6"7(,FG$A-0?<466?H1@%@@EB!56.9,DF)62'>$+D0=@;*/C7=?=)>1:9FB!*'A.'/"83A:3+,G3-&7#'#0H"-:#:/#FAB0?#E/,FH-;&@$E&1!+"+*02F'F"2'D@60-/G@C81"'"95%8
@r3261
CCAGTAAAACANCTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATAGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGG
+
-<@%"%,#.0,HB7C5FF@F:&F-H#E=70HF:7@?EGF'227(*+G&+6+3;-,?B;),<H"F(6HFG=-,+#@%&CC381(!D!2)!>6#3F&9*1)G<!H%5*&B:(A&,C)!(=>4F7@H?B.70%:$!C1""F$+G
@r3262
CCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCA
+
@*H?(0*78(G<6$037<"58%HAA&E$+.3&&"%D+7.+$:<..3!3*)&!E&2&$';F+3
@r3263
AAATATTGAGCGGATACGGCNTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACT
+
"@$AC*;D<E%E/!8:5H32G)GAA+(D+H2'H-,@34=2,73!E8F@D36E2/$#D6?C6?,,@C$71?56G&A3.F?H6):)C1@><&!C&(G9,<6H3
@r3264
NACGCTGCAGGATAATGTCCGGTGTCATGNTGCCACCTTCTGCT
+
';0170&A'.2?19&;$/C?771(B@HA:E!@@$.C>,F(F8"B
@r3265
ATATTCTGGCAANAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCT
+
*?F<2#)?<(<!0)-(5?&,5AF4CHFH=50A8:F62(6H#0B(?>!.4@>43-D07DD(7*//7;
@r3266
CACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGNTGTTATCCGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCTTTCAGAATGAGTGAACAACCA
+
-?E<;55%=3;D<"G!$E-=.>2F=,>>A!=C6CDG84'D/CB>A)#1%#2<C(;0FD2$9%H71CHG>H+:-!7&-!(GBE"?.?>'1:&8$+/@'&7-.A.")07-*?7?3!!),!#91<*859>H%!=46"25!)9!B62<77E?#;A:.15/+BED0E<"03'!0,:FD+F4851CE9B7./,4A:18+$/>7%*@@D%68G8:(1D+1E(5!?#B@("F8,'&$E)A"1HG#+*9A8H&@6$=AH@C?6
@r3267
TCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATA
+
=$&8(+"0+$0F4A4>)?G0"%4:FD3B:)B';<!#6B/?C-00F4&>>,;E0..*@!,F7$H)$=9-/
@r3268
TCCAACGAAACGCACCAGAAATAAACCCAAGCCAAGCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGG
+
58=6#CC37%".)8,G6HFF<561=:4)E>C*G-A5+3"6D&=;<(&@=.7$9@#F)*"$"DG!)*C;!@3&(A?=BB1"'(A*C9
@r3269
GACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGAAAAATCCTGCAGGCGGATNACAACACGCTGATGGCGCCGGCGA
+
%DE%%57+9(.7E/'$7>03&0),+<3D&2,(E&=0=98."/(=$E.//&'G4B0$A%BGH%>%)C70+E"B0);1'&-F48ED)?.),D;%9/&<8E+$>;5.2),@;$/%0"#A.H!7?)4;@!7!F:,-'0;67703G)+(22H6E;35H-04="@700'<=D8#@F?&*%?->,A%=&>45G=H@$C,8#$8;CBD
@r3270
CATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAAAA
+
*+$(**+(*$*$"&$)(()+'(")$$)%&!"++$(!''%*'%*'"!%#**$*"&*!($"&'(#'$(%$%!'(("(#'')#'#%$#)$$"+#+)'*!"$&+&%($&$'!('&*+*(*"$%
@r3271
CATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTANGCCTGTTTTTCTTTGC
+
7#+5.!14H)63!5;;4H+H)AB.)'E/:59@@1$"D#9%#GB<5GH9EC;GBD/.DB(#>#$=<3D@<-
@r3272
NATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGNTCCACTCCNGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCC
+
'60H1F1A3(7<,-1>.F:?#H+G5#>+D/1&82&=A@,G7."HB@AF2.12D"@6*/)AA/67?#/B'9'@=#$>',74"%!7?;AB")/-)0=8,#?;A*E6)''4?$5!?+>A-,'C4@:D(G2%,)4C52/4=??H.1768!#=024F3751':08&3A:/)=#)GB5GA0H63-1A,7E%@)(7,9#!;=$-5A.82<!C-H<@'>/CC%.5E3C3,<D>"D9"(9@$@HG9A;8!"#"0<;6B22,"#8C>.<<&-3&6"1%*
@r3273
AAGAAAAGANGTCAGCTGCGTCGTTTGANATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGNGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGAAAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGNAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATANCATTTTACGTTTCTCGTTC
+
@<C6H43%+A""A*0--89<+B6,5/8/?'8".A&<(H,-,;=B<3(.GC=F+6+A:%/<1?B$("&&-'A9@E1?/C'95.+(<"*=+25BC)*H832A;/;3$@DF(3&2)E<41;=&!F/+%B6E.*:,87@*!$1C"F"7!)*F?B();A?>"?,62CE--*',/:G53'=::%?$//.H%"H;+=F1/7<DB/8F//4A0.)B!'@<B0H<7!;G7/DD(-8+C'9%E@A)1A%*6+/15!DBA,?9BC?'8"H?C"5">G@(),'/22,0890@:@H")?%10.3+)'5<2&%9'?$7&?#)9GBE3H&@F'B3$1A
@r3274
TCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTNAAAAACCATGGGAAAGAAGACTTA
+
D<(*E/C5;@B#)35F'32=:,@3+52$D//)H4F'5$7&!!G015EF#A0$=C!>F2#1$4#E#D6>8;5<&G-8%D&&"G03'+/+:"+"&3?&:.>0A+4G=6-C9G7!C5;$H1;?%!)3"4>@1
@r3275
NNNCNNANTANNGGCTNNTNNNAACNGATNNTTAGCGTNNGNNN
+
!!$#!$"#"$!$###$$!$"!#$"##$$!$#!$#$!!#"!$!$!
@r3276
ACGCATCAGGNGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTC
+
GF51;B@'CC<*AC@6;E8(/$)$:#9++<?*DH'!A2+HB:0("C-8*:33G)+:5A-:>=1+.&$95)%$?"+)?>-3;5:?!&@6""A?4A>(61!?<E:.%=(&
@r3277
TNCTTTCTTATACGCAGCCTCTGCCTTNATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAG
+
&$+*))!$+")("%%"$)%*&$**+(*$$("%#"%"#'*%"($$#(+""*"$!$%'%+)!"("*+#$#"
@r3278
GTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAG
+
<AF$D1$H&#.2"271,;($8F##-4C#*"C':=6+3-/%&;50!==D$4=#A25:+*9#E$1<(E>>@1-3.%45,-
@r3279
TGATATCAACCCGGAGCTTGGACAGCCANATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGAT
+
?@6.7"<.$03%+5?!-#-*)9;8'=F35!=0AD.6)"9<>'3BF,D-A;28,0&GC,;!C)<)C69-+9A,8;B3AD--F8=81:B7!)B79E8>=
@r3280
GAAGGCCATATAACAACAAACCATGTCGNTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGNAAATTTATCAAG
+
'8A6?F4<52HBE2EE27A/?><-93D+H+5'#&83"?!69'/2'85DF(91(<''.5G?"@4@<&:,:,!8?1%580DB8B84HF-H+$75'1+>G2D9;3;
@r3281
CTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATG
+
/6B9FF6)8B$H@1A=G!7!G>0;H3=&:#>,(?1GD-0:5<@4'
@r3282
CGGCTGTTTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCNGCGCTGGC
+
<E/4B8.-D@H()29>7:<#E93*)CCDB;,67":&&,?EG#*:60%+40<0!B9#/$79;3EF'
@r3283
NAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGC
+
&>/"++9@/!C18G@?C7?!?C):5605'9-0B;6+:2=8');!4GB@)@>+=+A$$,EC&@38=7AH/3>H)9/43'8=4:E
@r3284
ACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTG
+
/("D#37+H.D.!"!A0/&D+GH+0>.3E0=8#%4AD8/G4.6?04/BAF)00($377..3,4(
@r3285
GCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAA
+
G4#4/153--G;A8)D'+<5:#'"*7+.0<EG,6"C;1@AAD1)B$/GAF/7E8;F-')>=&!+&EB;(6G-8
@r3286
TGACGCTGGCATTCGCATCAAAGCAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGATAC
+
=+)B(A)"9#4,+=7:2)D,A1G%4=4;:-%B1B4DB.H>)1>7;.B!$4DHH598?"B)=8&05>%'D%6<(B=.+<3;@(A;GB7-)A=?(9071:DF75D!0&8:%0D<3)713;-6=&6(3-@>E,)+/@F3EA!.%05/%3657<<5)*!H,;!D)4%H-#,#>*@4B/2E422E
@r3287
AACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCC
+
5'>"'**'+$52!E2)EF8&1B'):".A+9)6'F*A:CG4?DHC(
@r3288
GCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTNCATATCGAGCAGAATGCCGTCCA
+
=47DA81@85#592E)C-5(#7@(=-)9,88@5%82/#;385%&F!/+H:,B=<*E*C/'AA=.G?1B>F5,>CE??&<!A:D*%'<26,?ECA@DD&G,>?G1&42(
@r3289
CAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGCTATCGTAGATGGANATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCA
+
/G2&4.71+$;,>@@4*D:<$E.%(*G.9C60&B2;4=,03#9;+E0:(.%5<5A3+E7G(0<2./H+9H'H8;8B.D+D-!)@06C3@GG,3B
@r3290
CTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGCATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACATCCGGATGCTNAAGTGATGGCAGGGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCGGACCGCCGGTATCG
+
2/5-F5AC8))4H34?<G91>%B#.*@H;8*29#89+#'6$B7G2+*0;2D>A&/G0>$&6*4*$/.F&&+B,5..6.4,E&DF2F$"B,<#H01-;B0'9*B?2/%DHE1EH#'5572"")6@B%$F@-CD,C68:8CA$'#<;+;#/#;B(8!"'.7)/#BB1/';31H:=?4>327<+>441E@2)!<C-+HG!/44/"A(0.$/<H&8-D;;&F$:A7(A@63D@7C%)1$'*);=E39B)=5A.95*D=783<!E>%=927H*D)*GG56,+356*#6
@r3291
GCNTGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCAT
+
)'&$)++&!%!&+"*&#&)'$#+$)+#%*')++*+))$"#+*')+'*%"%%+%%("!(&!"('&'"%*%""#+'#+)#%(#'!+"$%(
@r3292
TCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGAGAAAATATCGCCCNCGAAATGCCGGGCTGATTAGGAAAACAGGNAAGGGGGTTAGTGAATGCTTT
+
D+-A5!$#4G,/2+:CD+0-'<+5/91':=46;#(=%!8*2-=>@G>;.'*:+44(:G%0@;37*'='1C/7?E!7)/"B(134%$2?:(B8!"D$54E6>?F:"E3./'H&=!7<*8A1+D0F?HEG
@r3293
GAGATCCAGCTGCCAGTGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAG
+
11%72F.0CE*9''*9;G:3&-G;G:0D-G071FF3?*DC7-!'EGB-/)'HF*&+;+*A!0'D9.
@r3294
ATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTT
+
/0!&F/7'-B@1#$($<H++@<+D)AB)*'984)4$H,14<D@*G!*CG'#B?4?;+%0-C!)+3CF6.;>:-".2(01*@;D
@r3295
GCTGGTTCTTTAATCTCGATTACGANAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATA
+
5E-H+%FC8B@F=B1=EEF./*>AFF(-9@7/*AF9:B?*7*+G1-!A"@*?"!D7DE61,73,.(<3#)&3;2068A&>=)5;0+@6@%5.@(/#(!34.A
@r3296
NAGCTTAAATCGCTTNTATCTGGCGCTGAATAGCTGATAAT
+
":3F*8&"E93C)>.%><))#+,#<-.0%/8<9?4G+H.:'
@r3297
CCNGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGANACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCA
+
F%21'?#,1-6*F./':AA**20B&H+,4HCHE#?!,27F=>:3G6=)08?+B8-34*:@<2<'6::3)75+0B+@'-D5!G-!,!$,9/(:$F-!1&3=9'(D$#<14;8+.(F':@A:8+G;HC#'7
@r3298
CGTTAAATCTATCAGCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTA
+
HGA)$=9@<5<D5C$>-!!3"*FB'20+68/?FA@"1:=G8+17B8!*D&)5+725;52>E1+=(0=.6A4)$:4)FF-@8$**%?%54&3B+;;&)B:=%+&'E7/2.32)B&HF@:(79009+D<BB-
@r3299
TANGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTC
+
%%!+&'!)##%)*+(%#&*)'#$%"!)"%%!('+&(+#"!('"("#"+%*++#$#%#(#+'''%(++!#**()&
@r3300
TCATCTCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCA
+
##!#(+#$+%%&&*(($$)+#&*$*(%$'(+!!('")'#!!!")!%"(+%)+%##*'$!*"*)"&''*)'*+'$!*)#)*#$+*$+"!'"##
@r3301
GTCGGCGNCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGA
+
+'))&&$%$'($+$(+(%%(++##&'"(("%$#*!*(%$$)*&!)#&**"#%%)"*"*&(')#%+%)*
@r3302
TTCAGTTCTCTGGCATTTTTGTCGCGCTAGGCTTTGTAGGTAATGGCGTTATCACGGT
+
F-)EH:1/,(%=H.<-6'16":"B#EHD0=2*;:"538E;7>HBH0*0!)AD?E/::>
@r3303
AGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGA
+
*$+)&""&#%""))&""+!()+&*+*%%*'"!%*"&+"!'##'(&)!!$&"*)%*+*"$(&*#"&")*&$**
@r3304
CTTTTNGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAAGAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCAATACGTCTTAACTCTTCATATTTAGAAAT
+
-GC":>8'+(49$HF91*,C3CD#E<<&@(,$3#?:<D7%E9$"=&A>>F$==1B'+E%0(5-01C)(.C-!F?@59@97G+E,@1*<G29)*?7411(C2G<6+96#<8G7H-8%1179H=,!&0'3,9'D8H1$<2HC)=EF;(2.3:/F':1&68",6*>F%B958(7
@r3305
NTATGTAGATGAAGGTATAGATATAGAGTCGGCATAGAAATATTCCATGAAGGTTTATAAGTCTA
+
#57<:3+:*5>1('6.%@#(#/AE998B46;<-(C88D&C-3E+?>4F?2'CFB03>,1F/481@
@r3306
ATTAACCGTTGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAGTCAAAGCNAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGNCAAT
+
5"DH#')=,?*=#@66E8#9";&1;=DF282###5*+&"H%?8+:1C;-%6'?88>D10AA+&/-GF=*5A;./#@*#5/+B(F09&9%;&C#D(/,*BGCA7"D@H.=:;$=6?@7-8'5F!9E87-"<1A%<2?%.?7'4H*G<4;G0':+?
@r3307
TTTGCANAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGAC
+
1$H27$E@"$=2F5>7/?95'A#+<HH@-)?*#:>D&4!.,-&4,:;,79,E/5EGE/?35//E?B
@r3308
CGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAG
+
6:%$&%$4,::5"&(,#3E2!#(8?5%0@G"-&.+53&=>;-,2@/A9/5G&,@/2C5FA8()BEC;62>")
@r3309
GGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAA
+
HF670G=E?57H)/1C$/+93!=';7+%;;7'!A#3664"*A<709&&4'C6=F-+<$)B%&1G%*BH!??$//@AF9@"3"BB85-!:1B@?A%;@
@r3310
TAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGA
+
*=06%6724$G?/G5&(93,$A%@29GB38C=!%'9C""3,7341(;5B4->6
@r3311
AGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCG
+
B/-(9/#;0@35@>8$G6+5G7;6-<$6"(B"0&-14B"4*+=-&$F/6G-7-$;1?(-9D+#7E4*98E2D=7*2+*)C@C98*+3G+GG9.1H*E;F-!&<=81AH5-
@r3312
CGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTA
+
F("7G,'-E:.A$1%&%;D<$%"&.1,8'H(5/5;D72:3-8,?,"*:2,?6+'#
@r3313
NCNCCNTATTGNCCCCANCTNCNNNGNANCNNGGNANTATTCCGCATAAGCGAATGTTGCGAGCACTTG
+
#(&##'"%))'$&$")"'&(&))!$*"&!"!$'"'$!&'$+&%**($"(#*$(*%)"%$#()#"(&&'!
@r3314
TACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACNACATTCCTGGTGTTTCTTTTTNAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAG
+
7E*6%-1*9C7F=<1/15*D=(<3"68:.FFA2-F?A.E"BG-D6%?A7HA,$EE-;;G#=03D*7!F@<2*5//@0+8?;=2HE9=@7H#E5-74B3&#D)5;DE@<3$-6C/1+"%0'%%4+.$)/F=0!"?D%G3?&#B6)&-89HH&76"4"C.=1@DG?1)D64@)32DD>F*7;9B"0A44">?=@080>8(1B8
@r3315
TTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAATCAGCCACAAAGCCAGCC
+
G'2=7.!":5C#)4B1(67&')A8C@<:6>!.8!$4804/"(5)EE%$.B+*$%-E1A2#)A933',&($
@r3316
GGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATT
+
G48?GCD1<5.),BD%4D2'$B>.0$H0+13@DD52H)@=3>8*#G<>D3106AH,8.10
@r3317
CTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTNAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGNTTTGTGCATACAGCCCCTCGTTTATNATTTACCTCCTCAGCCAGCCGCT
+
GC9A>;#'-G'5CH*<>,0?$+!-*F.9'D.A.!#C?8EAD00"1&#/!!40%%=/#(H#B(-C(+2HF023+<&$A3C>:54'+9-#%(A!H9(#%$;4:A5-.85(#>!%>+;HC3'GGC/?0)<7?*1'5*4BG6!.-C-527"1C67!6+(?$5&6@EB?;8D"H3(99<8GD4>FD(=(@(!"-6"0>,6=FHG.$"3,'.*0!"..(*$-C8&:)(A3"<4;%/!9C>(<7B2BE<E5#93E1G4?8=3E?-0+.D&=G-"C10+((H*.2,$$-6*"512?;*<F1%F,-&6:=F897;8-F(5?C6?<A=5%>+0:'$@H0%F;C/D%BA9E
@r3318
GAATCGNACTTACGGCCAATGCTTCGTTTCGTATCACAAACCCCAAA
+
:6"41@H+/D$GC::6A#+C"+;5;8C=(4-98$GB2$)+D9-1-'.
@r3319
CATTGAGCCTGTTTCTCTGCGCGACGTTCGCCGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTGAGTTAGCTTTGGTGGTGTGTG
+
*-">C*F8E@<?18<-G113GD5)9='0*@#$0D%*#05:!H73&41'B:F#C<>3E/*!=D2,2?/<%0(.<0-)*F3=!5/G-5"82
@r3320
CGGGCGTGCGCCAGAATCGCTGATTCNGTCTGTGTCATGGGANTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTT
+
2$;EC)$9"<!5*F)2HF6B-9,;C10-!EE-;''3D>759!-!27@.DBG,730E98:+)82HB/+'2&!)G&<..,3)$07$?
@r3321
NCCAGTTNTNCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGCCACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCNCCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTCNGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCA
+
##"##)&$(+!$'"!&%%*'*$+"$*(###)(&+$+$&&"!!*%&&'"$##+&'$$##!&$$&#''$#+&&"$!&*#%%&&%(**&+)#*)'%+++!'*&((*!'%()%!!#!"%%+!)"(!!'*)$+#)'++%'!!&&#')#)(%%!&&'(%()&*%(%++""#&**$*+&+*#*($%$"%+""%$(!#'!)#''+'*)#&$(*!(+'$'#!$)()!%*&#(#$"!%&'"&%+&")*)*""("()$+)##('(($!#'+'*%*$+"#%))*))(+&#)"%)"'$')'()%(((()*"(##"!%***!%+*+"%&)%'!!*&+(#*$$%""#**)!"$!*$'%'#(%&$!*&+%+$(!&+!++&%'+##
@r3322
GGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATNTATATTTTTTGTCTGTCC
+
(%-=+%A0:H%=&H/352"$F4?1,?30#$B'G391H"4".2EG<9F13F0?CGEH>4@)6%>')"=D,93:783*H?6G
@r3323
ATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCGTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGANACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTA
+
9"@C:54>:$(:F":-?BFA?941EG&$G2"!>+:F"H&,"7.C17HB>?1#A6H/3/*#.7C&8!G>8$;H9'@2$H.>D&8$*&2D(#DH!96$F%%BB=)B/)6'5(9B?:-&*0D*1!"E3--9&>3+H==0<#75.<B)*3%126!G==@:<>!F$21%'"($!8;"A&(<5D4H<4.>""/*=5(=G0A;6B?%@,C8:=.2'C<3&'<"9*"DE3D&F+9H4B:>#:E+;G30,5$8,6,16-8+$B"+BE<0C5FD5F@"@;6!HD%85B=1($5*4G7<4C'#>A&
@r3324
NATATCAGCTATGCCGGACAGGGCGTGCGCGTNGAAGGCTTCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACG
+
"@4'23$#<C$6FG43,'4)6:<4"4B(!<$>+#':?B$A.AH8E<+)$?H.8,"?+3$<!#:0&%%6AF5$)A6%8B1+G!>FG'93.@@((/4>110
@r3325
ACTGNACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGNCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATGGCA
+
;=;5<,.(*/?<!C1=!).8>F+)-BD;*69/-(?)7(A833#:/@/9BFD>C58@*60G3%+-$+30)/7B/2@-@A-"D@C<H'D.?=!1.77E:#F(+F.*A0&##)C:,?E3B6B87?<)7$D%%B:5A&E=GHG/BDG"#=F==,1-''&B3A**3@.&1D
@r3326
GCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGC
+
;6'?=9H('BD$#*F9HE,<9639"9!A&36/9:)":A0)2!?,#!-3E3<#A(78*6?$1;E7';926D4?<.E=E26('C)89>33-'(9H13,!E;ED9+=2<(%=@"-%>>:2!58F2H(6H0&>%A+AA
@r3327
GTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACAAGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGGTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTG
+
B&7,7E#=H@!@&-27?D#3:H>FA:CE>A-#'%-=B*9<@1C2-9,G6,CD86,338D97,*<<<A/;'A3F&F5.4#;6@'G<9D$C:/((/DG9<6DH""!F/F21$!)"G#?F8C$1F7@(,'<?>5DC>0-*FA:<G9B')4H,&5'#=>%2<E/>'1=<57&FDA?A6?:G.F3-H7.'>H5:#4*@*6BC?+D224#8>)623=*66*.<*%H748&/GFC.FG@AG'##;:&7#+B6-E)1B&45=*:2/5'+.A',-&6/4"++/F'H+5?,)#D5=%#:&&&6$'E0=8:*7976;?606%H@E
@r3328
GGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGG
+
)'+&$+'#("**)**'*$%$)**"+*%#*)#+*($(&%"$&'"
@r3329
TATTCAGCGCCCGTACCTGNCCGAGTGGCTTNCCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAA
+
+9D522D>#G@7:FF%$60+CB17,H=?-G4=%4A9706.%)&6,+4E,)"$5(!#2F62(>$64'=#A;B>
@r3330
CGAGCGTNACCCCACGCGCATTTCCCCGTACAGAACAGGCNGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTGATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGNTGCAAGGGTGGCTCCGGNGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGTCAATCTGGAATACGCCACCTG
+
$#+*!'#++""%#*$")*&&$'!##(++%!'+%)#&"")$%++!')#*(!&(%%*&+($)*$$%%#'$+(&&"(!"((&)"!)+*&%&%#%$+"!%+"'%#)$(*"+'#$!"$#*%%&*&#")('"'$+#*'+#'"&$#)"%"&&)&)*$((&()"+&"$""%$+*+!!*%"%*($$&()"$$$(!!!"'!)+)(&&#$"'&$#$!()()*"*+)!"')+""!+#+"#!)(%%'"((!#"#!(%%!$!+$#))#+$%"&#""*!%+&+(!%"$&"!&*#&*'+&*%)#"$%##(!#)($((!$&*#)&#"$
@r3331
TTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGT
+
4-G!A68F&D3%3*C',4?9)F%2)'3+;005F?D+G29,"2
@r3332
CGGTGAGGCTCAGATTGCGTCCATCAGCCAGANTGTGGCGCGTTTCTCC
+
0-&6&+AHBB,#*7001.0,>>1#;C%<H/7,%1E,@:D*$08B4%!43
@r3333
TTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACNCAATACTTTTATATTGGACTCAA
+
38@!E4;E/9%6"<7(==7G'HB7$BC?;5A=3C5H!'D@B"E50,-!*96"1%*4@C8H9&.@
@r3334
ACNGAGCCTGATGTGGCTAAAAGACAGGNACAATCTTTACTACCGCAATCCACTACTTAAGGTGAT
+
#&#$+')+$!%+*'+*#!*()"""*$(#'"#%+%%+)&%$+!!%$(!'#&&%''+%!")%%*!#+)
@r3335
CTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCATACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACC
+
:7;GF90!(H>?-?0.*'/<6#B=BH,6?'>7A2<<'F'3-@*?!0'C5(A#3;+><80:(323$*&=<.%HG27?BC#"/,)":+-=91@G%8'=<16:9/5-+!7"+D5&%0)GEE*F9'&F$A1++F'!,+.GGG"8
@r3336
CGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATGGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTG
+
CH"@$#5#60FAD):%C!F9;?7G(A,B+BD51;?%B.0GDD&47#3+2)H2$$"F9*?@H+8;)8#;.52G6<,0;8!@-6,9D5AG+EC7B(6/)6-<)8=-*<.8#48!)%;7,/0@=<D*:<!@
@r3337
CTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATNTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCG
+
H?F<'G9$/E@F$DC%F$"A?A"=0D$850%,8&E#41B9D4G!!:C$@:<"343E8C;A;3&A/3$&B.)"?!5<),7<1?/<;G:2HA-*-!/=<,9)+76H0GD%7<D,(B4AG&9>7:C!"*62/D;;'(0&"%$%F#G#3H6.?8'<%%5)7
@r3338
CGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGAGATTCACCACAGCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCAATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTT
+
;-7*A;.15C=4D.2%,:%<C@+0AB3B*:)B44)@6H%&>=,2*E#898(D3B.F&1)2,7@:6!8F-D;!C>G.@+%1#-(A,D+<AEH@3':)$$#BC.<FF5H3FE/$8FH.#",5B1=F:?1E.H5?7G,BB6G>>)*85G7E01;C:*+2613=.C0C>).'+3:@472%*=C8/D4F426=)1>-:7(';:D(H'<B-;3DE*@H'-8<.%
@r3339
GCTNGATGCTATCAAAAAACTAAGNAGTGATGAAAACTTTTCAAAT
+
**#'$%!)"+&'$#+!+(+)$"%*!%)&$(#+"%"#+$(#'+*%))
@r3340
CTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCG
+
&*)+$'*$*''"&+)"*&#("$!(!'!!('*$'&))%**%'!%$(#$$%*!$(!((+&(*%#!!$&*+*$!+!'&)
@r3341
TGGTGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCANCATTTTCCGCAAAATACAGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTNCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGAGACGCGTCAC
+
<2%>25=B/A0$.;F620?%2($$#-+</'$7HF&1#6@1!&-81+H"<.%.'7);>3;A9FF.=>1$;"*-?!)-)0$:.,F=5"'@H685(4.F*HDA<H<%(36%85,:DD)6D)0C,;?A*@6(-7-/629@=E0F:,8',3*;.DB?F7%;-<5.7(!)3C:8*<!?&=2C;4=*DB$C;2;F<3'.23)AE4#%.8;!/D$='3$$41CC81';?'/'.4A-F+"*E-56H($(F.07-21,2F??5.9D'3"F9A>&$AE-.F;&E4,9*#,B>28AE$:@$E,1:.1+@5;3B1+.#+3EEB!1,!14*%;"
@r3342
GAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGG
+
@%80A*$&A&>,9@;2.B998,8.#=@<E27D2!@@;>4.E)D>,0G61F+'-2.4?6<!"?H*EH-F".,8@(B$3-5#3@1"D#;+A5,.%'"4'8?0?E")'.A0AG,/0C%!+-5,(=1+0@H08-CC".'E'.E7)G$$:;)CH,!E@+2$?C<F.0DC:F?D(B:@A-2;HE)2/7.@/;(&(D'9+EG8?"$D.;?'"=A91C)A8>;)AD%1$&(F(#"+G?7&4!;(08G(.
@r3343
ATTTGGGTAGTTGGCGATCTGCANGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTG
+
8,*.-ADA(:?2&4$&/94-..H*3*&1,6;2'&@!G$,)DDAG?"8,7=(-B#.1C--+8:/7G+;7%0&'>H"0#A5(HF=A)D<
@r3344
CCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGG
+
=3H%???#/$F$<65$-"<5&273?&*?/CD3"-*':.$D&>)DCH73)>11G0D7($C96C16GGB)2G8)E?;?&%H*$AF5%A*7FH(/@+0*'4@CG1E&@:"+73G?.4F-BE,>>7F9E2(@-!:DHA=6<*45+86?B2F7C7C*=<D/4C
@r3345
CGATCATATACATGGTTCTCTCCAGANGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCNAGTTCTANACTCATCAAACTGTAG
+
?3E&#2=,$8*C<E@<'7?B55*A;!=HH:#B**.$=%A6/7)"1.@DG*=(>-'(&<!%*28%*.!=@/EB(9*'#0!6E#=FD:C*C:%F
@r3346
AGGCCACTGACTAGCGATAACTTTCCCCACAACGGTACAACTCTCATTGCATG
+
.17:'+C:B;:/!5=!;B7-,$C.=&71'/D%1,F'F='#!D*.=-5)CC?#"
@r3347
TATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATNTGCTTTCCATTCCAT
+
CD0H#E<'?E8<($3<'@A@G!:<H;-7(239D@(&+:!1&7+0$(D,'$E#"F:7C95ACAB+,-=""#9"!20-)
@r3348
CAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCAGTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGTAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCNTCTGTGCGGCGATGTTTNTCATAGATCCACCCCGTAAATCCAGT
+
?A=<(9(&A>2":+E-FCE0()E:+G(=)$A"&*3=&/@?'C84>#30"2BD8HE/$%3)8(B)G<%!1%G/=#,<+$+:#4@89#27@3G$>3"C<GA!?#"?#"H.E:4:GAF$32>84G8?/C7-F;:';:3,H61;.**6<2.()A;54>C,G0'(+?+0';!B)@'F7>9>8!)="E>607;40='59B7<?-%??6%(/%0/!'@!E,+-6?D,E83>>>#0;7=;B>&:1HB(E.C%710;>9@6G,@:?=54$+D,,B860>%/E?#1(D*1*G1D(BBH%%&CC6,/2@&<>1A1"<:-*-F;F2,%36A%E;$./),-680-/-%.$?)*'
@r3349
AATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTNA
+
(C<@@<6-/#!$(.@$/>G9H!<!))F<0A*-,.%<:0,G+5%G5-6*;@
@r3350
CATGTGCACCGGCACTNACGGCTNTACCGTACAATGAGTGACTGTGGCTGCCCTGACTGT
+
@*.=:H.8=(?2+4(DB@7":-3<*AG034D?)77B"H*)7''70&".?17H+C'HB2E<
@r3351
GCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAATGGCGGCAGATAAAGGTG
+
'*+%$"))!&$'&'!'+##(+)(+!%++%(+$(+)!+(%$)+(*$(*)%)%+)+++!&+#)*&#*#%'"((**(*$*$*$)#&+)*&**("%++&#*'"&!(+*#($#$%&!
@r3352
NGCGGTGACAGTCACTCCGGCCCGTGCGNAAGGTGGACATGGTACGTTTACGGTGGGCTAT
+
"B"&>#+HBG+)$$:HGG$7$%E#4>@+01@G54+G"#,$-H4-13D)=7A?&#==&FC-%
@r3353
CGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGANAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTATTGGGGAATGAGTTGCAATTATTGCTACANCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTTGATGCAGATGAACCTCTGGTTCATCGA
+
A%C8D-?-"@1$0DD=5%#EE5D;F(%<F:144.;F<A;)GFC5ACE&@(41.05<)&49!:!3!7:)!"<"$8=@.-<F>5;2B9D0!3:9%:%?@"2E"+3H--:C@E,:%1D8CB:1,H2E4DC2$(=A9:(?A?"D.?&?*47),.#>0%BBH19@<&0CA)%4,1".9($4!<!9!@%7.E$$.F,=&C#*8B3?48H3!8G87H>1E@#8G75$93)=HH)<&GE0
@r3354
CACAGTTCCCGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGC
+
?=E:66;@HB96:?6>B&<(*7%1?&+02)BFGB&>0G?89&3:>@D"&;7&2
@r3355
CCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAACCCAATGGTGATNCCCAACTTAGCGAGATTACAAAGCTACCTGTCAAACGGTGCNACGAA
+
?53*">%90E43E=E9=C<.<;GE/GG.%'04A9CAA3?/H0C&H8'/;1EF4*$G@-%6EA.6C.!+?8G/G1/E'B3B%5):B;+B:"&H,"+'FE673/1/3C)@5)6:"8-
@r3356
TAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATANGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGNATGTAATAGAGAGTAACTNAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATA
+
%B8#/-;H!"A'*'#+(4G<,><"6$DA8%%81"=6(1/+'0%'!!0<B486>0@.H23!7,5G6>B9#$C/C:>3;=B2H+;:E;E/-H9+>@E<H?@4:<#07A<@=C#!.;8/+">9,?!<F0'==CFC??:@#5#D'0/F#)*95@,%?C?3:.(?04GG#,+"#GH(;$6!&D>8>>>A''BH?%)H+9&F*#$?$4>!:>#980$,
@r3357
TGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCTGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTGAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACNGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGNCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGNTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAAC
+
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
@r3358
ANAACCTATGGGTGGAATAAACCAATGGACAGAATCANCGGTAA
+
'!+$&"$%+)'##'$")%)%!!)!$&(!+*#(#$"*!'+*(#%(
@r3359
NGNCNCNNNNGGNNTNNNNNGGANNNANNNTGGTNCNNNTNNNGCCCGGGTNCNTGNNTCACTANNNATGGNCANNNGCNNGTNNGGTANCNNNNNATNNNNANNGNANCCAACTCNGGNNTNANNNNGCNNNTTNNTNNNNNCTNTAGCTNTNANNNNCNTNNGNCAATNNNNCCGCGCNNTNNNCNCNNNNNCNNGACGGNTNNTNNGGCCTNAGGATNGNCGGCANNNNNTGCGNNGNNAGNNNNNNNCCGCCNTATANNNCAA
+
!""##""$"!"!!""#$"!#"#$###!!!"$#!##"#!!!$#!#"$$#$#!##!$"$$"$!!#"$#""!!!"##""!!!"#"""#$$!#!"#!!!!$#!"$!!!$#!#"##"######"!!!!!""!"#""#$$$#!"!!!"#$#$$""#!!$$$#"!"!!"!#$##$"!"#"!""$$"$!!#""!$"#!#"#!"""$!$!#"!"$$"##!"$#!!"$$$!#""$$$$$"#$#"#$$!$""!#$!!!$$$#$##!$$$!#$!!"#$!
@r3360
GCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAAT
+
/B.@G4&+(?/"$AADD(7<?9)!<H,7,2A,,=/+9F>*1'F:.5%8'"F'HAC/13&&?5'1C(FG=.6>0)":?8#.!E*;EE5!F$=%;>."D8>+$6?E57(#A,B3D4$E"B2D'#$9>F9?;34%8+0D==BH
@r3361
TTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTNAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGNCAACCTTTCAGGNATGAACGCTGCCC
+
545+59C6/4;*-&2F1=+B7=*?+4EF/F.!1.GB-=-?!%0!8>0#C(5;&A)=F6G-B!528*HBBG)F"7%EF!!<7(%<H6.4B?-@E12=*>G)/H.E!E?+7;$'1H7@<;A@8.#;E-0*
@r3362
AGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGANATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGNCATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACG
+
DB05$,&2:)()4#H-+A<&&((B2#&,AB8HA&>04C'6)ADG*E/DAA/(?(%%%B?$4&3(F*<ED>9?8A<>)'$9#8.897'.&*HF#,F)B8174:/*::A+430/7,34>G1"#>:B&8055E<H./)"$2(;>#!<,BC)D51)>&"$''4:#G$'#4&8C"C+)!14/"#:!A&6210.%+'C>1
@r3363
GCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATT
+
25%310%(#9/)G&4))'>8&")")1H".0!(5=7C#-:EH%
@r3364
AATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGC
+
6/4<*)22FF<:'@62-,H9#*=49E9)8H#$*C91B32*2=>@H*99*0?/#H7B<C&9:031@"<F!D#$&07@.9F)B+2!-$!30&,51D$3:E)"BA.H8;C$3<*(5/A-:=228<)GAD:-6+/"
@r3365
NCCANATAACCGCNACGCCGCATCTTGCCGTTTATGCGGTANAGTTTGAGTTCTGGTTCTCGGAAANGCA
+
!&*)%)++!&)$"#%++)(%(&($*%&()&'("%!#&)$%%"+!%%%!'*!&('$!&)(!(()+$$#!'*
@r3366
GCTTAATTACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCT
+
+10009(+EDH>#.=2/(:E'7G!'#:)3&+$DAC-"*,)$!&,=A..%74,8E@8G"0:;+6
@r3367
ATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACC
+
@&DBG.%*)*E4;B6;;9(E=?:!H*9-A7!/D(&6BF1C')FH6D-F3
@r3368
NCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGT
+
!+("#+%%*%*)!"%&**!#**!)#(#$%('"'("$!$"#%+#**"(
@r3369
TTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCT
+
@0H8')*2FE5-7A",668>@);7E3D%8:;EAB*?.AHC-3:7!
@r3370
GAGNANNNTNACANNNNCANNNNNNCNTAAAAANNGANACCNTNNGTANNNNCNNAACCCNANTCNANCCNTACTGCNGGTNCTNNNANNGNGN
+
$$##!!"!$"!"#!$!!""$!$!$####"$#$!$!#""!$"""""$$"#"!$"!#"$"#$$$!"$#$$$""#"!"#$$$#!"#$!"!"!#"!#"
@r3371
ACTGCCCGNCGCTTTTGCTCCATTAGCCAGAGCNAATATGCTGACGT
+
#12<+&;*6&D5F:(+094G"18D444<5D=G095=>6).'5",$4D
@r3372
TNTCCGTCACCCAGCCACCGTTACGTTGTANCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAG
+
73,E,/&-&0%!A@@F!;!%3$3H%/G/31+?04)#D4+*FA$C(D1!F1%B.>.)*D0D33@3,F/'<>-$>.3=E54>?<--:&13(>A:<6:*'0E2F71G+=@"@94H.@7B=%.-A4/C<31G,/4BH=97,=CD36B<9#4*+7,.$(?6(C9=/%$).C7-=C>$C!
@r3373
GATTGAGTGCGCTTTCTACTCGTGATTTCGTTTTGCGATTCAGCGAGAGAAT
+
2:'%,;:?2&6;@1=@,40(-(6=3;.4A7+&C;,$/';#1A3'++AH<(>G
@r3374
CAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACTTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGG
+
+GCH,*=0"%0@9G+H=A/<!+1)1(DE!4".=F!H416'A)#;H0H>!#'%9%@*4#*(DG!-9$#94FE&(/H&27>42=G/GB&;!)D.AGH(60!",B?'
@r3375
GGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACG
+
7,A1(3%?*+-.!HAF0!B=5!?%;?.*#D,C635)D#"F90'1E'##7F9;HF&D6?D+HA@;<C=;EB,!;+9-4
@r3376
TACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCT
+
9!!GH;?)'"3-3G-:2'B>$=#>#A($6D4'-..+H(@95<*-E:$)H;@601A
@r3377
TANTTTCNGNNCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACC
+
'!(*$!(&&"!#'+&(+"%&$)++!+))'#**)("*$"""!++!!*!+))
@r3378
TCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCNGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGGTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATC
+
-6&,./4G>ED=HH9CE%*9!!*$!#D'GH0EA0!FAA0!E;>-*,'D7,>1-G#EHG:;C."%A3>E<3+,</F!DA#A+A06A--$EC&GE1)84(D;D=4=92,G%4;!7$(6H4<E'DG=D(,442'?'4'FCD"&>63=<7:F<H"4#%)DF=%8,'-(09?=#3+@-7'&@@/<GED'6!!4!@&>)#-!@/H#
@r3379
GGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGG
+
719-/!<.1&>3**%*8)+'=(?1&!9+C;C?&A4>+/4-/.H!
@r3380
TGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACANAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGC
+
?/3)"C;8*/;60>#DC:7,!E1.!D@?/4F10>G!!07H37?0';837E*.<,.G<!-8AGG8G*$1F4-5EB..31+%'ADHH,H9#:;'H?H@?!?06)CC)5/,.(AD;6$.<E6*C63%B$@+2=5F&>&D&HF<GB4?/.,,0#+@););H=,@"F9H.@'G=0-+D,7.
@r3381
ACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGA
+
<+22.4!9?<#:H2H>G)85C;:7B-FAE"4*%""?>#G%-+H49&9B8H9%!FE!,9
@r3382
TCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTT
+
>C5?:-!+A-.2@.B7A(>G&9@1>;BE='F,!6<2.B<8#,?>9>!>AE%@*+!*B;7<*6F=3A;@?FC?A3B3-'-B=5(7#&<78H+G@.#
@r3383
NNCTCGTTGTGGTAGTGANATGAAAAGAGGCGGCGCTTACTACCGATT
+
"#+)$)+)!$*%$&#'%(!'&#$$*$!"""$%()()*'$()+$#+*!'
@r3384
GCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCC
+
>(&<="-@4896&30'G%=5>5$=HHH4.49F:8D:A#7+D>?&0/
@r3385
AGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGT
+
C43<8.4$EF?A/1'9*(-,G-C@<+5E??2/-FAH+"A#"51DA#('C;E#61:.<CE,5%#G&=BDGCDD<76#?@4&GC3->'4.98#."4@1C2<+8H0$H<.,;,F;7C=
@r3386
AACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGNACGGAACGTTTAAACCGGCATACAGCAACNACATGGCCTGGTGTCTGTGGGACATGCTGACCCATCCGCGCTACGGCATNGGGNAACGTCTTGGTGCGGCGGAAGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGAT
+
@<EGH.:$29)=?DHB9'6>154:.+%;"./@+A/30$0=;7:G+:2;$41+71:"/4-AD$?9#)'!2*7?9-7A20>=.#.$4,!5/>@-D-&,@C:G$BC'.(D".&#B/$#%/FF#5E+=(FB":/D:((+C83:70#$9&)4#*A+#E+05.D>F,.9149E+.9!(C(:;F/-D&/=31*&4F;-9E:<+$%7A+$#,(%H"!F<?%E:+F9G)786?9D$A"C.'HA@@/@9>'2,)6,H*>,D6C?7-$C-(8=);1.F1$'!!.%/F/B3="-
@r3387
GAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGNGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTAT
+
2(1',>,"1-?>+"26:06$<?9(-;"A480?+1-/D'DAH?.H-!6?(.(FA(@&=)8?,A%870>-G-,24'*+55D*F>'5:?$7B0G:;!/48?7*3/D)33/=$3<0/.+329?/*A!(6;"86<6/655@#542.F,F(*E3==D.<G-:8?.A.;-(;D8
@r3388
ACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACT
+
-"7;3"C4*1D=(+,HC,A9>0$%.FC"'"'!8ED4H$1443@:-2*'"-3%<0("-7H>-@+E.?!06/=GH'C26*A>$H@+#GA!"H/";E&,3,F&3D1G"0>D&##*)@H(/%.%@$,B?+8!:,=5BC*A/%6)8?!=:0B%8,9;4C&&5<>9<61.9;(:3:D7&9+0).:F-'&:(B+<-D=9<$
@r3389
GATATTCAGGCAAAAAATTCCGTTGCAGATGTTCTTGTATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGACATCGTTCCGCCTGGCTACGTCC
+
?1;F<0=%03)$H@1+&"/7;:%!==),;B29F39.@#5%1*=59=9CC$:=+6?C57414(-2&0!C6H!@0%/%;8<F?;?2!##*"D82"=4.@5@?6=D+1"EE&8)3?:E64E5:+@>"
@r3390
NAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTT
+
)?"*=5>(7@5+6.!?37F4F'0;H5*7&A/F*9!??7(2=A:9=9&3A5C=,47'.>B<+D>$H'#07F:
@r3391
CGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATNCAATGC
+
,E::3*E9<9<25EA8B*E,G2<24DC=G>+,(*%8.F2,'DDD4"0#6BB'0&)%$<H4=+C#(.F#GE+,;D-%9"GC+8*19#B25<;=%3"@EH"5%(&D0=80<*+5!(B6E)#!AA-B%@=$$"C-3#E*:.3>
@r3392
NAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGC
+
.</.A'&H=.0@98A2"H4,0*7H@>G*6(2+C'$C,F1F"!,@1+;1;/)#<3?;(&*15&/5B*=(BF"%2H4=&-E>*(,:
@r3393
CGCCGTTGATTGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATNCCAGGAAGGGCGCTGGGAAACACTGCCCTTTC
+
,F5!.680A@?<5H/"GB2:%47#3+0$B?A**2-?8<9E7?2/?3CC4"!57F?H3!2B"H+CF7@0%-?/5%?!:8C.B/=)B
@r3394
GTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTGTATTATAAAACA
+
B@@3F8$167/7$@D3GH:"!A>$"-?)2*$@HC1)0#,DB><H'%=B2:*/)*>*!49)(,2!'$C2!'C6+GGF)+:?20A)A/B"DD6#
@r3395
CTATCTGATNCAATTTGCACACAAGGNATCGGGGAAATAACGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTC
+
*1+451<F-'+;60:273G>2$GG84!'!)(0(39$BHDG9'2,(;G),(,/AE7#6,.2-45:$"-BA=4,@$)'D76D&4/70C4&(1!/B6D8B:/..D&
@r3396
GCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCA
+
-?*1E,<=D8C1>)H&D*819G0B!#F2117')'A49%2/96HE:.;@54-*@$-H7/-E&"1<.'=6%/>:G2A"??9+,
@r3397
GTTCCATTGCAAGNCTGAGCCAACATGGTGATGATTCTGCTGCTTGATACATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGAC
+
7-8@/(?'%GF8,:+'"8>2209+G&3)G(*6/>0$(765"!C&4'(>7%.:,8,<<0"6662GE68;5%D8,'=G$5%@C#H859(/=E0$/E5G'*=15"*0B6$+E#"1@G<(4-+8#
@r3398
CCGGTGTCACGGTGGTGTTCCGGGCTGGTGNGCAGGAGCAG
+
$0*B/+:.;(14D?$0D@EAB:H1&D2,3+11889.:+#+?
@r3399
CACCACCGGAACGATGCCATTNTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCT
+
;:F;5';7.D?4%:'3)?.-)33C;?$?G;@CC!,EB4&5H8+9D5/<-1/11E/5-<7+B.<C=E.C1A:7HC,6A:8-0*2G2"5;B<=*90E?E=,GCC"('@2#E-?7#F5#5F)0<$:"@H7,1&83%.DC:
@r3400
TGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTNTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTNGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCG
+
C64<>=%$?AG72$@/##G#.$81BF0A"@&(+HB<#;!BD=4CD'B"8-.E//3"',9@*BFG$-$%-5EF*+A(>!@F,;H%!=@>=,C!1D4&4*-+-$G49!D95="H!(@6$,=.8F@.5!61C#/@1DG1*1$B?AB"CF%HE!,7+&?!$4A%(F-@*'$E%@.4<>@F066$C:8>0%,5&'%2C7;%
@r3401
GACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGGCATCACG
+
2>0A/609>>H!=@4)1)/A$?<E:6.C34!5D+@H<,71G%.8?C23@6B(;('DC4A8)4'%E'4C<08)!H
@r3402
TAATCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAANCAACCTTCAACGTATTGAGCGCAAGAATCAGCGCACATGGT
+
!%#$+#&)&)'((*)+#!$%$&%(&*$'#+*'##!+(%!(+"&)+"+$##!!(+%**!!*$'")#'"'"%()"&&)**#%)+!
@r3403
TTGGCGGNAACCAGAAACTGGCTCAGTTTGCCTTCNTCCGTATCCTCCATGCTGAGGCCANTACCCGCGACATAATGTTTGCCGTTTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTTGCATCCTTCCACTCTTTCGAAAACTCCTNCAGTCTG
+
-!C6/"&6HH@.)(5&+;.+&03$E&:>E8H95+G(H-8/):,074)&B%/'#"?E759)*-F68$=C#@:+1,%G:.8C60%!D&3CG1-&".(=1C%,/,;B@0*A*H'6E.5>$2BHH.$4<-!))&<2(D7C;E*/)7F5D3#,+60,D83'87&&@H'G>5/.-&4
@r3404
TTGGGCGGTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGANGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCNGCCTCCGGCCAGAGCACATC
+
?!,.*G88D9705;3D2<,-1=G25-6%D0D517/;#;G'B?!;3@6.+D6-=9&519(#!/1?%EG,<"BA!8**6$3=2F%+<D<FE)/1>!>HB/-05*&$E7DDG1?@>B61>(#&!:!"967&:60348<B;70.*-!:"1!41;'!*6"HA;@&
@r3405
GTAACCACCGCGACATGTGNGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTANTGAGCCCGGCCAAACTCCGC
+
5>),;'FH8+04?7.+4%(3=%,6>61-E.B<404HH<=69<<,)16>/<D'GF)0:1G#1A*C-@G$4$+'6@+/)+89!.,G2?5$(
@r3406
TAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCG
+
B/))?33.*@=!F7=#F58@4DE844E#;,A+":4>)#1D?$D/(B51F#;#'&;6D)=E,<<EE5/1.-G!#D2*&>AA*/.D55-A,))@!H&C#'*1;:727-6F#?5-9(@34@C@EF5$?:B@"7G"#/2:G@G99%..CFC5:<E%,(D/'((1#GHD)F,0H"+4H&6.GB,HH0,C4G>1.':2&D"+9#C:
@r3407
TAAAAGATATTACTATACCTTTGATAATTCATTACTATTTA
+
=!AF7(>*%6%1!3.FEA7(34482;+=,C=7)H$:$H<#H
@r3408
NTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTNTACTGGT
+
"GF5A<3!/,?F@8::9@0)0.85AG:$D,-DE3*7&.2"1%%#27""E)F;0(:'7,(@'&1<;7=#.00&8D193C*#/G0"1-<+C!2G
@r3409
GGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCC
+
2.%$6.2F25FE3G#"-BF%$#>#:@4#26-:F5(4)@?)5B*#?D%+1,D<!#-/C!ED/<D$0=D4G0(
@r3410
ANAGTGNGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTNTCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTANATTCTCAAG
+
#!#+!("((*&$+'()'*"&+*)("*$%&)$%+*#$&*+#'"!&&$)')&*%$*'#&%+*%)!"%#%!#%)$%'"%'"+#!#!**!"%&#%#'()*)&%*%##$$)$*&&%&"&&%"&'!!&#''$(+!)!)%%#'&))##)%("+')##"+%%&%'*$%$**"("&%$!
@r3411
GCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGNGCATGGCAGAACATATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATANA
+
;2AE(&?@,:C7#83;+:!#7:="9G3?>,#""3?&-%6G;-19D"A*6#D:7=6-5-D0EG&7A/=F?F5#G@B;?DC1"01#+)@>-9&!;,#)+="0#:8&3/C0,%)F:,9H-<"B6G8@FF
@r3412
TGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCNACGGCAAATGTNATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGANTTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAA
+
B*1B53(?*#F2)'!(9H5(<E:/0$.9F3(7>+-64FH06?%4H/D+,0H&;@A%"A.0!"3"7%6)&!")!2:0480*+6G0@"GDA2CD4$>345#D-3)G6E+&%>>/E?'><D-%>%D">,8D=812+9)AD&&+?D/1<')=(>E/@$41)1#1H,.!@7B29"A#2DA/)?C*)(BC+A-F>*@,D*(A-2=/3D$!?B8-4/=E@+
@r3413
ATAAACATCCCTTACACTCGTGTGTTCAGCAAATCGTTAACGGCA
+
*6*A79%E<'2,=,,5$0@#88G,$)0.3'(947813-:7B6!*'
@r3414
CACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTANCTAAGGAAATACTTACATATGGTNCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTG
+
D7%303A5#.02#4+;4!E-;%/(@>>H0D3!0688C/'92+?$2;95.3D56#57=#3-C<53(6(..!$>F<(4-A"*)D("7#.:?6D2&>C9>83+/AD"D(-7!B#;G-;:
@r3415
CATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTG
+
H$=77%"2+;DH!=25'&#"6H/->=#<)"+47<=H./#-/1;@,.&23E;7"7<1DHF<"07BC&F%%$G@!><*56G+"-G!$A996.*377FD<7,8'9#)+85=<7,C*#%>.F3.>6'(-D-9%!;9:-D<512F5;.7#?8+!07
@r3416
TCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCGGCACGAGATGCGGTGNCCT
+
""*++')##+"'(($$&"+#"#$")$$)!*&($++)*()$'$%(()*)%%$$)%#%)&&!+)&$"#*'%($#"&+)!*)&&%#+*%"'&&!$*+"!$!*+!$**&"%%")!))**%%$$'!&$)'((!!&)"
@r3417
CCGCATTCTGTACTTTCGTGCTGTTGCGGATCGCAGGTGAAATTGCCAG
+
0,1&A&(89G&H1=#<BC2DAD,%A/>0).."?&D$?*-&&AGACB,+)
@r3418
TCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAA
+
99-+-@FB4?G(",1B*!;1C9/077=3A!".*).;&-F6*
@r3419
GCATGAGAGAANTTGTACCACCTCCCACCGACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGNTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCC
+
B>-)-)#A1%H7'$:BD1G=H)5/("@A2E)H2D8G'C6:0,969#C=&)B,@4%#F*F#BB/%"!:;-6-'9.1%":3'HC.5@.F6G5>?;F/FB)D2'#G9;+$C53480H$?4.<G7,,(&:>4(&E!A,1"9.1H@>/D?'1A2;;>G&F&-0,0#=26*8H!?$4H:<*@=,2*("=0E)D67A%F48-+'!8.:@HA4<;(;?.28$;=.*/$08#!1D/-<424':*>78#.9+61458F&7::%;&1+5#463&B+/.<
@r3420
TCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCA
+
)?/F+1&04E+2#11$GGA?E$BB'%D78G3$->C<(2&)H:AG""##,-43
@r3421
CTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCA
+
(/80A5%34&<F=9*0<05..+;62&>8H5:4&1.;E#:(@):BG2#
@r3422
GCTAACCGTGACCAGAACGAAGTGAACGAAATCNGTCGCCAGTGGGTTCTGGCTTTTCGG
+
+#()8:;>7(7-:HF.%%-D*."-5B*:#&,#/)H.(/6B$+'*3=*#D3/=5F61#.D*
@r3423
GGGCGNAGTCATTNAAAACNATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGT
+
!)#"'((*#)*(&!#%&!*"'(+'&)))*##&&$!&&#+$!#%%!&%!(#+()"&%+"#
@r3424
TCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCT
+
0EE0,H1D96:)?8.=G)B!-,E*27;!!<<9;)F(=:F7(>41-*)
@r3425
CCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCG
+
.$.=!H>@+'#A4+7+#C<:!1.;@300%5./H'46+#(G"6,H$E2
@r3426
AACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAA
+
4$#D<,)/F;@26*E0-6,<$90'"(2!D<9&'8D1B7G0246$3A<GD/$)'897<D2&/30-7+D+A<F@:2*CG"<.##')$4+<%H6E='$E'<>'H=E*7>)#F1F
@r3427
CTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCNTCCTCTGTCTGTTCAGGGGCATTATTCANCACAAACTCATACATA
+
6F8B""%(E/(7CA(8)19+G88@:@GA#43D4'6>3@';B."/3=;;CGBB91?<<$5*3"<B'G03.@C!A1&)+8)
@r3428
GAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCG
+
(/5F:3$@?)!4C9F)?C;B-9,/*7%,76'91D%7,,0##(#:17$5E)A/%
@r3429
TAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGA
+
,>/**!4D3?$<+1)=,+!.<%F7*4(*,<?F,9:9D<$!8;2>7"?%2F$=0%$E((60A$#1F97?*B'4*=D)*>&*=*:5*37.&'$@4+>0<9B:$HB&":(%?G27'C94,
@r3430
ACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGGAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACNAATCAGCCTACCCAAAACTTNCTGTCGCGTATCCATCNGGTGTGCTTCCTGATATGCGCGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACNGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGNGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTT
+
+!#%#"$)#%"!#+"!#++"#)&("*!$))')'"%)&+'#&"&"$*$!#&()(#)*#"$(!*%%")'%!+""+##&&$)#'+*&&'+%&("%!($&')'!*()*(&!'%)+'&)*++!(%)')&&+&+!))'*()()'&&'$+(**$'#*#$$(&%"%#!!#+"+*)!('+%+&+"""+%%#%"*'+(()"%+%))"&"%("+)+)))%'&!)&&%(**(&*)$%*+)++(')*&%'%%++'#&$&#%(+$++&%&$''*!+'())$#&$("&&&'(*%'$$"*())&#$#*(!$!+&"%)%&+#&&))*!**$*(#'$'+)'"#*"&")+*))&*))&!*'%*$$&&($)&($'"%%"$+++$!&&!%"%&"*+($!*)%+$&%%"$(#(*"*%(&%')#(&&)$!#''*('++++'"+(")"$*#&++"'!##(%""())'"##*'&"&'+*+*#+&($!###!**'!*%'"(%'%))'#")*%$$"*
@r3431
ATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATANTAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAA
+
=D#2G,D$%F.'F>&-D(;=F&+H7*A6:.4C$-7AHF#H.H,A90:9H#4:$3;(FA6%>:,5#1(5"3A*/6@C;65,9E4&9A?3*-%(E0.,>@BE"?')A#4HF&(4+C$D8D6G2=E."@93:5?1A5"47,8D.!/>=E80H363*6*=D';@(!8!BF*@>/D@*1?34G!8047D##:C=2
@r3432
CGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGNCAGCCTTATGC
+
=C2@C"E2;:6@*<FE2.4-1<->%(#!?14%7"1,F1(B)$@,8+.#&71/H"'></4=28H-/2H?6=@-0F%:-C(/A/=7"9@&D.
@r3433
TGACNCNGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGNTAC
+
0HC#89*11%86-2!?#E;@D&2=24F=?%4"92EE42,9B4F00*-(6F
@r3434
GCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAG
+
G.B&%5=)33)&HH.8A-6&<B9;79*80,%1B3@/7AG.)/%:#;$C>8B#G=&#./)8(+"DA55E4,%6H6!@H,$:"'/@
@r3435
ATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGC
+
3G'H:+C&E2C:";9(2-4%;#E?'79&<.$<2G#7;H,>>/
@r3436
GTTTAACGTTTTCCCGTATCCCCTTTCGTTTNCATCCAGTCTTTGACAATC
+
FB7=A3;=C(2D+$,,B%;+B@CG6A*$(:((C,1/1<9:H=1B,9-9E37
@r3437
TGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGG
+
37<;$=;FBA97D,?9",,=D93;CEB.8$&&=+FB@)"/;0B.%:,.&4!74'2F9868.5/8#"D+1A92?C+,?05D>)'<:42E?:C4@2*9@'<:F%:>#
@r3438
GACATCTACTAATCTTGTGATAGTAAATAAAACAANTGCATGTCCAGAGCTGATTCGAACCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTT
+
/22'@E(+H*#>+C#5*5#B+@4HD$.'(FGF9H#*&#;$<*<EE<EE.(CF7,@&C$<A?64.4F*8+HDE+5H=,6-*6+"H;:+*F.E@"#9B!<$-+*;/;<-+1-)G4!%C
@r3439
TTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTA
+
>:>/A"/(55>+,)!*'"<$?/-)@+D?&;0=/A2".!+A=FB/#4'8&F-@<0>'#)F3ACB>17@#FF&"%4B@CDE&.
@r3440
AGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTGATGGATCATTTTTCCAT
+
!:GF#)12E-HC,4+A+-&0)!!$'B<5,9-.3B2:8D<=>D5E73A/+03."$;0,96>E$,($
@r3441
GGNAAATGTCATCGACGTTTTTATCCAANCTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCAGACAGA
+
AG5:1+A64(4$*8".6-B%%C0DF+/5?-#)+?@#7='!&"42=59,!,(,49B7(-C2,<*&,./;#-G"&1(63D!6BG9$B1146H3EG0)9.9E9:/).?,5C7=7#E+D6>8$%@)!A5#E(<,E<@8A<2B0E%#GDH
@r3442
CCTGACTGTTCGATATATTCACTCNGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTTATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGNTCCGGAAAACGCCGCTGCACCGACAGG
+
F4)A9((;D:13)!(-&<34+2F+7-&>7+2D<"#(%=6H#4->#/D51"!3318:>"5%;!7!)H(/E3CAH7+8#(?.D'9B,,5.29"&A3</F%>B:DF-'!$<79;5AAA428?A@)$!#2*G6#1:B<:E!8EE;"4=
@r3443
TATGCTTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCANGCTCAATC
+
)0*48::E+>25*7*'@6G@>.3"$,7+8?>EEB(((.*GCC3D5H?C,?8'"
@r3444
CTGCTGATGATCAACTGGCTTTNCAAACTCGTATTCGTCAGAGGGAAAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTC
+
00>(G';DBD$7!""44D08',8,739+8<&+;"!+:;3<("C2%A;#2F.'1,H03G;5'01@(7<E:??>CE$417?GB>;:.
@r3445
NTGGNNGNAATGACTATTCCTTTGTTACAATGTTTTANCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGATATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCA
+
%"!*"&*+)%)('+$&'(+#)&%"$%'%)'%$%+#'*!"*+(++%$!&)!''&(#))*)$*$+#%'$+&')$&$&"&")'#+''&'&%++&)%&&%+*#"%!$*+#*&#$##$+!"*(*&&(&"%+'(#*%!$%+(!*()#%'!%*'"$*
@r3446
TGGAGGTGTCCAGNATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGNCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGG
+
89+:,"8>.(01/$>F:@/#;1<H0A567+<:+!,*=6G#2-+2H/*$9.+?(D;+FG?&<3.E#&<>)D39(&'?>F@HH&G$@"1,1A#(B;?@,8><D33=24"4;/(<;%
@r3447
CTGCGCNCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACG
+
::!@0)!'A&?/07*+:45'C4"?-#BH?>5$8"0&"8C<*FH6$?D+&#&"@1/!.
@r3448
GAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATACTCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGNATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGC
+
EE/;:>C'%:+3:D1!A!-6"(!-C@33-E::(719D%G&8*#C&2B=#191-940:7GB(G<07F&!0$('>5".=&2G7536&ED7*)0>$0880CD7(=F-@7.!D$")>#H#(-;>8::,8G#59!-4G5%A8)':3F(%;790"C!C.-A+F729528.7
@r3449
GCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAG
+
#F35A*.'5)*<*GA*="C:DF9HAF,$=6H+'!%'/$<5H2
@r3450
GACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCCCCCGCGTCCGGCTGACCANCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATNACCTGATAACTGCGGGCGTGTCGTGGTCCGTCATCATC
+
5@!E-%3<6=7(8A*&EB23).54EG#;'$,+0A,;$@B1DB7A"*;$0D/7(9=5)00@2-1=HB"A)H:1?<:,4/@1ED'72"4'717=A+>2E#0H&G9#AAB62:8#F=&+:!CAE=(.19D=31C9,!6&/<60#1D"<
@r3451
TAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTT
+
EA0,13,G83$,GFGF&7*7E6"C;,E>G*90,8G#4G&2'+30;A(@:6G.#:;D47/<+)
@r3452
ATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGNTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGC
+
<)B(6?-D6/:4F$-1%*7A7)/$#:<F&6/2/G3H=@-7G8:2120-3+G!-"GH(5#29GGFEBE.(>&DBF:+;:/;?71>=F@7,5+$F/47&15(+&0"2A?2"<3+4F<3B?A'C.01E(?5%F19)*(4#*0F)=>)7@=F3$41'AA/A6);+<8@'6B)A1/>AC5:!2&9!-;3=24,G.E@<E-)%D($@
@r3453
ATACCTNTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAA
+
3-;!?$$$+1AGEC67$)0H>)&17-1E!5@?.,C(1)H98DC>:;(,$>2=46H-*.1E@;#H.<2=*:96<<$;&+**51:'%2/$<.9A,?72/-<#D-+51;!F8!?(<6-'?43H.+=
@r3454
AACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGT
+
;#3!7;/C8#<3.C(-+?&:E0>8@5'=AB(5=?"?F)A()6@*-;>#(4+3?A7%
@r3455
CCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCNACCATCGCAGGCAGAGA
+
:?&0.+)/(0#E5?A$D,(>+&/6%AH-39+/B$?G0.5!+"#F.1EGBD8";3
@r3456
TCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATTCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGNCGGCGGCGCGTTCTGCACTGAC
+
A"E%DEE2&>)68=:5A6H*602?6$F'91"(668E7('0.!)/"2(9;FE@@&D?66A6@99H,"!CFD96$*>4=F83*$,;!874$0*<./?2-?;)8,2:=F$).2F6&'+7)DC4!<=-:D/2A67437796>)1,)F&E.=F7"D%/7,H0--7";E(G7=45@E?DD?!#;@>(!5",.$EA<!/)+23/15!#,E85CHG.2.9B5,?$
@r3457
ANAAGNAGAGTTNGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCNGATGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGCTC
+
*()!&#!&#*(%!%#&)'+'+&&#!$("#+)(')"*%!#%%$%&+'*#!'*)+$+#+!)$'&&#&!"**!%$%"&'*#($#"#$#!")%*"+#")($'+'%!#&%)%"'(!%+#'*(%'!+($+"#"*!!#$+%%)'$+&$')'+*"$'+##'###!)$!&#$+'&+$#+'"!)&(#'(#($**"*""(*!""$$%&*++$+*'$!!)'+)(%"'&$*"!*&!+&()!#!+%*'&)""*!*+'!'"$%)+$"$$+(!)$""&(*'(*++#")+(%&+()+"%"$#)"+$'%$'''#+"+&'+"!++++!*!!&$!'*')%&&(+$*$+'(+!"'*"""*)+#&$#!*'!#*#')+%")
@r3458
CTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTNATGGGATT
+
?#/=!<1<8,=2&#*B.9)/C!=>#D$=C?934(,*D;5=)D!1#2*H8+G?.(<29:0*H%-A-"F2.?"D)CD7.EE+A"-H2;8:G#+GD*086=63&?6C=-2+
@r3459
NNATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCANCNAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACAGCCCGNGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGG
+
!%2B3)+A/D0>.69E*)7B3'-A:?()5'"2&(6A>G>+F$*?7+;.8==-58#!#(B'"@2F553&E!1@H6G$56<@2!EF/18D=+,+(%5GH,B"F"D,H2'&>7"B9C%)8%$A&)2?AA2<DC>0#G?!7AE"5<>)+;*(*?>:D>B**F9:H7#F<@=$2;<F2E>2/:3AFGD"
@r3460
TGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCA
+
CB;@G<G*$;B9G-E'&.<0B2%-4$94F=,2F%C@5F+'%4CF8BD$*H-;3+4>!'B0A73
@r3461
ACCGGTNGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCA
+
H299%7:>B>B$A+3%GE8&6&%<C(!;*-H-.EEBG;B+(551D?>0.(=B+G/C!@@/<&>;7BE;(9'(&ED6EG@EB9#G0#C12@'1?(8B+,">)
@r3462
ATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCAGCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCG
+
EFEE(%AD3EED&+B,0&5/;2-;$;B=$H(%8E2-(B.?1-&3EG@5!8'D'(H$+E/8/72#A(0)('*+,F8%7D$"-A.:AD"*$*0),#=GACF;GC"!$C#+1"$%<8.98=9:416(!>F6!6
@r3463
TCTTCNGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTACATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTT
+
4'B5?",GG81(H#@87>@"0E@9-4<)<1>;8H&AH5>8>%-")+(6E+!H$95-83.3<;()E6969H+/%)E04;+!26$15$+EA:'$0G8B53C;4>B66H,8!=9&.@',-)*@,'6/$D(A63#31?(A!*&;9<GD"G9?4=<D?!;@/(.-(?<B7E2@HA%899+@H$;";5?."?6;01A#7%%*F'-3<H>$?F++F'#0!2(<E"3@@)F)+*80;1/?@(.<E.-;A&:#>>''$!*54,$"!A2E%.=-7,B2*+E$%'H+-E#>18>:E"/9:C/3B>C$9=(;A6+BF%C#',2F+71>5C
@r3464
CAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCANGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCA
+
<%'*&EA9&,;#<B;(F0$A$D07(C%-'-%1;#),(>,9"50%"!,71$G..*..7)1$47%/36;'%%=>G<#H65A*0;+A)/CE#@(6/>E5'F$48,H*G*F%(:04%@4EC3A<;1):4E4:
@r3465
CGGATGGGTCAGCATATCCCACAGACACNAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCC
+
($+%%+$&&+!+(%*+%+!('$(('#*!)$&%!%%+"!)#('()$&!$&)!'&)#'&%%%"&$(%"
@r3466
AGGGCATANTCATCAATTAAAAGTGATGAAGAATGAACATCCCGNGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTANTTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAATGCTGCCTCAATTGCT
+
+"'++")*$(%'!#*''!(&%)*#&#%*+&'")''*$*&*"$#"&'+%+!)"%'$(%#)$#&'&&&*#"#(+"%+&'$"$((#"%+)"''*%!(%)$'"+'('$*"%)'&$&!)!%%%+*)&%)&!'%'('%)(&"!#')+!(!$&!$*+&%$#&%&'($$&!"%$""!%'*$%!"$!+%)'%+'+&$%%*'+*(#!(%+(***$#')$!$+&$##(*)$(#%$+"%(+)'%&$)"'&#'')$#'&%''"%*#*$$&%%%+($#&'*
@r3467
NAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAANTCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATA
+
/&C+EF2)<:D,$EEB&0:5+BG>+F28!F'.9D%-!@",$$.A/=)G/?A94@6?5,+638%?%*9-<+!49E-8'984B7B"E4'C?('&.=8#!7'($/=1/D)
@r3468
AGGAAGAAACCTCGNTGCTGGAAGCCTGGAAGAAGTNTCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGNTATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATNGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTA
+
11$"-8+$#!00CE.8)B',87G/3;88!"2+-='5;#!4'<E'.4>3F'B1:B"*:FB=AGGE@59E?D,H4!-FFC""6$<70<3+CE1!)3AD744(4/B>F/6%;&%++7A7D2*:"44<EG">8#"/##"%.%C*.'+G"+$;%="*-1;:?')/2%%73!521*-D
@r3469
NCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCANGTAATTTNCGGGTGATTCGTTCAAGTAAAGATTCGGAAGNGCAGCCAGCAACAGGCCACCCTGCAATGGCAGATTGCTTGGTGTGCTCCTTATTTATACATAACGANAAACGCCTCGAGTGAAGCGCTATTGGNATGCG
+
":@B4*30'157+<@!96A"H*&-4"?%#"E51FH(GD93G)C1>8454?H1<%$64!#A">8AH'6A;(BH&"">-@+F@A:#4*A/2=+-)H+,;$$0!H")F&?5%,$3+G<9;>4**C83<:C%H/?):H*>5G=!&H47B59&*G,'#/?<;&>2E/44:/+=47(317?B=!C8@+<$<CD-%1A?>G&..FF:8?=&A7##-20&@-B!/6!9<2(G=+',"C9=072-=
@r3470
AGAAAATAACTCAATGTTGCCCTGTATAGCTTCAGTNATTGCGAT
+
!&*+#+'%")%**)&"$"+*#&*$*")$*+*&$%'#+%*"!("*!
@r3471
GAAAGAAGTTCAGGAAGCGGTGATGCNGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAAC
+
DC#?3-/$2$"FFDE<F%9&A$C8-185HC<H:1??0(69<>21?&5CH#(@2F24/$;D-<2#1>6,=E1
@r3472
ACTAATCTTNTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCTACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCT
+
$'"#'%)**!%+(!&!&)#$+(&$%"!(*("$#*"(!%(++$)!)%+!%&(#+()%#!%)'&"&(&&*(""*(&)(+!)*)%!%))()(+$))"'+"$&'&%*##"!#*!#&''&)$("&&!%'&***""#'+!+!**'')'$%##&"'$)%#$%**"
@r3473
TNGGNNGACNTTGTNNNGGNNANGCNAATNNNNNNANGTTTGNNNGNCNTNGNTNGTNTNGNAANANTNNGNGAGNTTANNGCNATTNN
+
#$$$"!"!"!$#$"!!!##!!$!#""##"!#!$#!$$"#$""!$!$!!!!#"!"$#!#!""!$!!#!!"##!$#"$$#"!!""$"!##$
@r3474
CCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGNTTTTTTATATCTGCAGAACAGGTAAG
+
E&6(;&'+E,(#)/3?F%C85+:8*'0*F3"=:+$%'/@1%%5-@(?6!"?0%C",D>5)G3A+?EEA7?G303&
@r3475
AGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAAT
+
.010D'&.!4)-+H),$-)-+'*?5HGD:,/;--=AA:5"A0@D$&G%8,"4,E6<"(>237H#;0?)7??3D<@D&73,)H$
@r3476
GTACGCGCCCCACGCTGACGGTTTCTAACNTGTACGGTATGGTCNCCGG
+
+#%!!'("(+('$')$()'(!!+++!)*"(&*+!'"!**(*!%!*&+"&
@r3477
CTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGA
+
9*F(,H('7GD0HG,";''92/)0F:@,*$)42(?>F:5-.C>3*.02=29/89#/%@:@/#-96/A;'"&938<8/?8;.EH>C0,>?8@>0@$)&<1C18::
@r3478
CCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGNACAGTNANGGCAGCCACAGTCA
+
!+,&7*713B1,9/18!2+GH<6:*<B?&E>90E-C0%"#8%C/C,"-(,6%7812B?965>C7--';1"H+;
@r3479
ATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACNGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGNCGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTAC
+
/B!),"1B%C,2:%!>?D0G.B&?>#G#5"*5;9H!"##*C.B0.89?'E6333?F),<;F=%"<>@1!9'9C5/";;,G8%.:+55%?67H?63&093/7AF4</AD986!;"=,FE>%B)3)26A8A*$2"/<5:!>;6>"&=0H1#7;82:&&9!/'=,5A@?3C.?A7(6!*4%9)+7@="#9DH>G<"%G!E=:)BHE8EA7!)
@r3480
CAGGCAGACCCCTCCTTATTNCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTNGCCA
+
@'4,@D#B"/2&7+:**.,(B@B3%A0./G=+E1$139?;!5;3?.>#<8/F@@G.A.$)/@$9G=:;;&"$H5&A?#
@r3481
NTCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGACGCCGGAAGGGGATGAA
+
!&A#*4&#HGB"81+59+@%.>=3A8%H#9*46.,9*"!6$<A7>1/*63-B?=9,@G+=*!:@A>/9<G2"<#&C-D),6E'@A?"H17A@":*-27G&*,'B/C74&7%HC#-/CGA)=:0'<+0=!9"#756?
@r3482
TTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCCGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGA
+
>>=94<(1@;E(E:>),0<(;"/,7G9+;>/!#1-B"!GB2:4>%?87G?@"38"%3)%<.0EB1</)(*!#)94#:@(4!"(7()4?=2.>/4>:8C/:+%@?@!8'D#4$*2E4-6E5+GEH<&&5?%%(&&-"8$;'C/"0)</5"&<%$(C.,8>@B
@r3483
AGGAAAAAAACATTTCAGGGAGTTGACTGAANTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTT
+
,F"3.A31,$-*.(1,>A#54#F&-$BB!)(%?D"6&GD7"&51!/C943H.84.<%%'"!#$>.'H16$@
@r3484
CAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCTCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCTCATAAAGATGAGACGCTGGAGT
+
!1C?2@7$'7H*'=E331321@DE((9@(@,#3)4>#'.7(*"147(06H8=6-.0CGDB,?%%4=.BC4AG);&@#B"61%A$F:"A$%$)?C9$!CD7>/3D3B"+%/H2C9#:H#+$17EA6+=,-B&G
@r3485
TATGACGAANGATGGAGNGGTTNGAGGCTNANCNGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTNTTTACAAAATCCGGTANTAACTTGCTAACCAATTCC
+
$%'#(#%%("(*&#((!!'(*$!#(!()*%)**"+*&!)')+##%)(+')*(*##+%*%!&!++*+*!'!%)%)+!*&*%%(##+**%%'('!!*')+*!%&!+&+!
@r3486
GGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCCTCCTT
+
8+?H:?(#)215<A'G'A62&2F%(</9C&7B>(H>%(H"H!?
@r3487
ACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCNATGCCGAC
+
*8,<$!$)24)'1%&:@%3&<?$(C(;)*='>*=C@H4A7+)!4/:C7/7D#H'%5"E"-0()8)#%'GG>+./!6?<'-8'@5H12/&GAG2F70<'@'?H9$##7C+CC-9=B
@r3488
TTCNCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTT
+
*C7B'3HH?#?,@B-&?0G>&//$C?+;G<3,G?>$:;""64A'(..'A89<
@r3489
TGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCATGGGTGAAGGATACGGAAGCANAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATTNTGCAGATCTGGAAATTGCAACGA
+
#5/55"6?'=D$1<:*;(H'%7G.%7">6-)D!C2(G8:<7E-<"B+=43AAA6<H18=0)2'3>./7C>BEA@=E96"-G6FD,:0&70>*$:5G>D1/E!./>&C,!;)!*>F<8(&63;"A.8+@1''</F.A0;67!B2*'6$D-'??6:A()DE'36>(/376BBGH'D).+ADGG@?+"<(3:.:%7!!;))/AG40&:%3.8%2,+-(89$3)'-""5EHA.=A#*5AHEAB&%)/09D;2/D;&?48D=,E.B'4#:5>-31*$A1A$161%
@r3490
NAAATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTAC
+
($)42*1:3'H+,;9(#:85'E/>EE&@)%G:>9:<%B*@A+?FE78*9B%&#D,E!6;G=08B76'G5.>$:F4A5@&G=6%-!H>H("<B"B,'-@6F8A
@r3491
AGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCT
+
>8".EDC>"3B)-"@>>H.58;'4B:>&.8*'!C6#?:5-)B7>/8?$,0A&E+;
@r3492
GCCACTCATAAGGCGGCGTCCACAGAAAGGATTCCCAGCCCCCGTGCTC
+
531)9>20<D!<0!GB#-=D%(<5!@GE(GA)6/F',<$99%/9!;'->
@r3493
GACCCGGACGCTGACGCTCGACCGTCAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCA
+
?%!81*-4!<A-%+-+"C'F,?/F-0G.@A,2'.A2*#8$=>A#E0B),(<43!"-0@4%.AEG2(>?5:,?8H)CD9!&2#;D/.9%'-/)
@r3494
CATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTC
+
<C!B#!#.#-3'D9(B%')GH;B6<H0:;53=C(3/'>3G17%<-#H>>A.4A
@r3495
AATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGNCAAGCCACAACTCTAATTTTANTACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAG
+
.B&<AA;3)2-0C:8?;F9E-C2@-$>3+?G.+-'$3'%'/9/#AC&4G'?E+@00-;==!D+E7"68$$265AA=%ED$!"*G6*2(#D-#*B/49@D@!4"3-8C(C?B9304&$E:=/.G)41*!>-"7D=3(&?F%#>'@GF5!68B-=8DB(?!$>0?H<+G=68D21D+>?>BD>80*9C(=%(;/26?3H59527H?9F1G%:E4"*@*E%8B:FC&49=7)?01A1CE5(5<3GB/8(,4F'?%$DBA?+=A()=3'C!&EG8
@r3496
ATCCTATAATCTGGTTTTTGTTTTNTTGAATAATAAATNTTACTGTTCTTG
+
D":&9(7<@0&(:+*&H="".>@HCH5+,H@(C)<=D%"-.'H;4#8?#&B
@r3497
CATCCCCATAGCAGCCATCCCATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAG
+
.)%6!91)G$6'1!H:<&"!E735-"-(;=(0C*D-&9F+F;3#,180?2<1C'%DED>E'E>7<'"0A#(0G5&%>B3<6(;06G91//>395G<*1@6#.)0E48+7D0?'7
@r3498
AACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGC
+
2B-9&HB7(;8:+D//"#)B/>@B0E<?8G@+&20?1,33&4#<6G))4'
@r3499
CGNGNNNNTGAATANNNNANNNNTTCCCAGNCNAAGANGT
+
"$#!!#"!$##""#""!$""$!!"##$$$$"!#$"$$!##
@r3500
CNANGNATTTGCACNTNNCGCAGATNATGTCGGNGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATT
+
!($!'!$()))')!!#"$&*%&$*!#&+('**$$+("+#&")*#&+#')+'%!'%#*"+"**"+$(*%$('"**"'*)#"(((+'%"#*#!!*$$&)&#$#&%(+)$)$%'&!+)+!#(%+*#%++')(
@r3501
GGGGCAGGTGAAGGACTCCTTCGGCNGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCAGTCCGATTTCAACAAAACGCTGGTCCTTTC
+
A3?4@AHA<HAG4@AH@'H-'54%0?;='F7>E##72E6-=D3$=1!$BC8%%3@):C##5@&03:"5B@2@D!E2H@39,?$0+78G#8C6$1,*0?%H(*1@G7'@//%@:DA%0(<3$A?>#C"(!;'>9@>)2+,;<%9C<7-,101<@F5,,CF#++!.@&&>7$AH&C=&6
@r3502
GTGCGTCGGCCNGCGCACGCGTAAGTCGATGGCGTTCGTACTCAACAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCANCTTTTCGTTCTCA
+
.D;7*E?.?)?',(7".*!218D#/F0<3/GB.F849$>,.+EF<;<5)@2(,<GECB":+5"(#+715!+;!1/)B1+A9072!'&H)=E?%1!):)D22+#)):4#A7;.9"0<20/
@r3503
TTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAG
+
6/EE00D;=-FA7EE;<2@>(+,#D#575/H(!@E/"4*&#;%H;%&2(4'0.&8#7:&7A9F"*..DCC"A%.5DC&"1B:"<3-<E4C32&>BD?%FG!;+<5?D?%$)D3#,'7#+1#=>:(4+=D
@r3504
NTTCAGCGGAGTCTCTGGCATTCTTNAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGGACTCAATAGTTC
+
#&+#(('&&)%$#$*(!)!("&(%+*#"$+%!"'"%#'!&+'+)$)*#'(&'++&*!+)$)%()&%!'"&")*)()&(#"%#"*
@r3505
AAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGTAAACGATACTTGCCCTCTCTGTACAAAACATATNGATGATTAAACCCAATATTACATAACAATCCTCGCAGTCGCNGGGATTTATTTTAACTGAACTCGCTACGGNGGGTTTTGTTTTATGGAGATGATAAATGCACTTC
+
5/*C/&;:,>=G&!5$@4,'5&:.,8#=:5D8=&D@%9*62$H?3<3&2:30*<B4"H:+?1=H()+,3;H#%E>(..#>.3H?F-2+#!:6GC*2*?GCE&,8?1)),#!GE%9-#"2*#'"?6,)@99C8&1:7-4>4G1(,1HD3B5!G83&GB;F?B';'!G<&.AC?/(%G0@<'=):$
@r3506
CTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTT
+
7<HF:-5&:9-0)'4@>0B<(H2'!?/>=B@A&:C#5C+01:@$?190.&98)E*&7:@
@r3507
GTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCG
+
,4)'?!,1,+5>5&3EFEA()*$A=90B/GC&-1>,.#>6:<)AH-//:+<A5D493-F/4"A;!A#D*HA&<5%G(#+4F!;F34@-?8*0C
@r3508
ATTGGAATCAGGTTTGTGCCANTNCCAGTAGAAACAGACG
+
56G8<@,%*'*&01H>C7;%&B>$8/<H:8868&*=)#4?
@r3509
ACGCGAACAGCACCAACCGCGCTCAGGGGAACAAACAATA
+
(&($+"$($')#&#!'%((!$$!*%*&%$")"++*"$##+
@r3510
TCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCC
+
=&G5#H!H8'8B7EA4&3)-35-;'=6?H#6*F)4(&G=43G41687)6!$C/3
@r3511
CACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAG
+
9E.>-GCA%DF&D=.)*5,-/+:<4;4A*>H"?G(6%-'%<%645@-";45"=#,186GH.G'8.:(>9&
@r3512
GACTGTGAGCCACTCCGGCCATGGAGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCGCGCTCACATAACGTCCACGCAGGCTCTCAT
+
;$6-'8>/6(G>7?(*3)=:1$61//A%;=@+,<5/=,H<5%#A-<<;%E'$/1)=:=>6.55<'H:5C*2/@-)87<8:)HH7$8>6!EFB*-=@A!6'!A
@r3513
NNTNTGTCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCA
+
!%!#(''$"+%&$!#%#*#!+$%+*+!+&""'+#('%'#+!&'&+#+'##$)'!("#%'"!
@r3514
TTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGACCTTTCTTATGAAACCATTCTAAA
+
(<>,04+A-3)B&:;7*F()H(6)302D$G,:0"7!EA>/<64E(-1D,D5?4&,G/"29#F6+E1C>$&#-F.$-36A
@r3515
GGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGA
+
923>2#D*6=$<@)BH)=850E<!*$E59A/F?(>!B.,B2:>=*/26:8@/=;26(7<!-!'F:(*=C10,!@$9@<4194(7C$!""%G3(FE/;.$3=%/+C#B53@
@r3516
ATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCNGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACT
+
>E+5DC4>3-A((BA!;8!<6G7%?2#G.B<*%00>75,$F7%.,/26%G-8D86A4@HB"E('H(E1H:$3?=&E4&&:;)%4:"%0H1,AH+57G,<*?49>;B;;+).'+1!A))ED+0H>9=:D7A7F"D<A?6B%&%5-B?01=(601@&+9,HCGC"*%=91(=A*F&H+C+4?=5)33<$8+44240'(;4&"9,?$D*?"F;$!(9,B4G0?74*06GF1,/>@D*7'0);/"0")@%./+$0:0=,D"7$DF(7(C'CB/(,!1D$+3'&'&5C+:*
@r3517
TAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGAT
+
6<HC2+9?!.(-&@)+/6AE5*.89C?(4E7C*'&/:%27H?-696>A3$@:08FD/6@),>*=:@H"&(F"08:<5CB-F50+A)<81FG39
@r3518
CATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAA
+
4$)F,,:<F:%7%'587:=+'+3<118.E4$$61EE:=C+-526,-#.=&%
@r3519
TGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTACATCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGT
+
#/EGF+E7'-(%<>,49A(+'-378>11G#5(/-!-<&'%?"G73CC:,&F89;GH<7#@5+-!E,?)0G*(9"H1A!=2H'>F<5&A=A@BB%H*C5A+!5,";9<3)4G))7!?99&#>3$;+@
@r3520
ACCCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCAT
+
""+"!%#+*)$%(&#'$%#!((''&&#&%&%*+!*+!")')$'!+%'(('*"+$'%'%'
@r3521
TTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTNGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGNTGAAGACTATCGCACCATCAGCCAGAAA
+
*:)7"+4,H,C2G82?53/B=>,B2:3-D0%,&%H<-=9'.(=9'?G5?FB#(H<%F.0.>7E'H4&137+;*-0'F@6$>+.'7"3-H1"3F+=E9E!HC93)+F"H1+<(/'<;&@#56
@r3522
ANCNTNNCCTNCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATGAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCANGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGANTTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTAGAGGTGANGGTTAATTCTATGCCCAGCACGAA
+
%'(#((!&$$(+$!(#'&$$%&*!"'%%*$'*$"'(('!(#&$$#"*'%*++&#!*')&!!!&('!##)%))&##'"&'%&&***'#$$(((%$%&&$(%*%!+#%#()%"&"+'%)$$%#')&((&"%!'%&$(+****(*((&"%)%'"+*%")('*%'+'#!)"$$+$()'%!+*+*!(#'#!#)$&((")+'%#$(&")!)%(&!'$&%(#"(&&"&)&+!&*)((%'#'%$%%%'+&"%)'%#&%#(#!)$*(+
@r3523
ATGACCTGGCANTNGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGNAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCT
+
2H8GB1GG81C-=@0/@%%E#(>9;>>:-/CE(,(=E'4A:!%"B+(3AF0A-??2@<<?46C&5'B0F%/?2$:C",20/.,3"'*6&99'#,7=:A7F!G>.,+3CB1"AH>B&#1@6;.48<H)3+6F?>;>&4A&1
@r3524
CTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGNACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTNACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGANGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGNTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCNC
+
80<;C3676A%='&E""+>231&F+.)7G<05(/H'5#$;""3<,?H@A=13$493791<A=3*!$%<05C<==?:'8.H8F2B378)622")!>@&EE'%/1A$,/?@$D;0D@"598).)1G=2EB*!BE!G3%*:4*C:=/>%@=9"B"AH/+63E3FB#7=*+B<CF*/+.*-C97.(@-=C@54<#D':!>$>7F*H4)BB?#%A%7E<9$0:FH8F%CEFDG+>7B3$5F47B+E>+*=!!5%CE7#'D7E"!1!EA:%#*#+A-D*3,,=DC/?#,4)>#.9'G?(!@2'@*4<:$*;$'4#B39*62E=:"$,#4B5$;(A*8#4,0C6.D;/7,
@r3525
CAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTCAAATCAAATAATGATTTTAT
+
=,!A'7/!#.*(@/(4CA;>*F:H@=+3?3"5C/?,EC33!*3H.&#A%>HG=02#211)$6<%@#1$5&;&BDH'"15%6#E47&5?65%;A*.EB/83H;>%'>3GF&8'9))/=@?F
@r3526
ACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTANGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGC
+
BA%<C3;&:&?,ADD0@1,DC&/<(6=EE4DB=3.=<2'*&</@(-D*59:9,&+:A-$+#F4#=?*7">G"@$$>8"!(EF1!,'HF;$,?2<$:4#"6"2C<:89,CH&F<10)AF*H@@$4D%<>:
@r3527
NGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGG
+
#G>%7CC+;;+5,$8>F8C1?&:C/=%#073D(E,/5')!.:**"G1H=06*-.2(:=G=E'G%)'D;$
@r3528
AATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGNCATCGG
+
A8:B"6%!#:&A&80")(+*(F;2"<&=G27016&<4G7A68
@r3529
TGCTGGGTGGGCTAACGATATCCGCCTGATACGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCCACTCGAGG
+
>/?7&8!!6>D?B.&#8.4.:)BDE51<1+"9)%;GC;D:5H"'AG&@F?+9F.00"AD:21G%G##,24"/.))=,*C$5/*%0@@5:./;:;DD:C&H$-.56:;!=15&"C;7#=(;905%=%.>-;F"2!/(E%F#>G?,11G,E6161&E$71
@r3530
TCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGC
+
C@<9,:5;23!F3&&.1?H46/0/2"E+H4,:@'$<$,C2$C.DA#:F?03>89-%=;?><+;!0.<!4(//16A&=)*""HA+(:3(*E(82>A3992H(0,$7!&/.30A?=&.*=64$)",D3-$HD@%0!"-6;63D@A(:6D0#;5$8-A6%%#%4%H+#9?G
@r3531
GTTAGNANTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCG
+
$##)*#'#%+&''+(!!#(("(*+)+$*$&+)!%+!%!++$%(((&)%!+!"!&!(%&%+$$$%+%++!!**!'+&+)%!++#!'"$(!**+#%
@r3532
GCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCNTATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGC
+
CFD0@HB#)"79'(B'=/7EE7$B5F6!,!!:)?<7:6FF!<<?,$;75;<C@)4#&BE6/#HBH??"22:FE%/A*9%57-&$&#<.F?%<@.!)D4#@=*A$D#?<2?5F)BG>?&/FG75'AB-GA?:?B:EE8C+&9!%EA(#FADH09;(D,82D*60-.D4H#5056E)64,G%A9?'@7EG7A.0+:5<6(HF82,E(F-2$*%@(#:*+5"E
@r3533
NGTNGTCAGAATNGACAANTTCNGCCNNCTCCCGGGTAGTTTGNTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCT
+
"))'')'%)*%*!$$%*)##%&&')$#%%)((())*('*'#%*(%+**!&&"#$'!!++('#*(($*%(%##+"*('*&%#'**)"%)+)%!"!+##*$$#+#"(%"#$'('&"%"%)**((%""*!$!"!!!++$++!++#!$&#$$'#+'*"&'!(%
@r3534
AATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGTGTTGTGGCTTGGCTC
+
FA1>:)C<300$>GG/2.2(B7"':-#!69B>"*<;>3)4B%'@=;3>!++B!!(E./2;
@r3535
AATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCA
+
<D(>C!7.(B&/G$;00&4*#B6D!644<-,,?+E'))>;@.3<G$=9B@7$3,@#,)A($;-G'-3?9A
@r3536
TATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGNTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTG
+
275+(5>F2!3':AE-784?>>*6%==E=!E8!%4%08@-'H2>,0!>&9+5C@G=;(!/B34$8,3<A3HD9/:"E&D'H,+@!/BD5-B+?0"@)00#/?4&7DD+.G;-'E4H3":#59<5!2)"%:4'?0+2F.4=A:/E?>/23?C82;0.
@r3537
TNGTACTGGAAANGCTTCTTCAGAAGCCTGAANAGCTAAT
+
=A4*3%.$1$&%=B;E',9$#F63*H7E>!F!>47%$3'+
@r3538
NCGATGTACACAACCGCCCAACTGCTGGCGGCCAATGAGCAGAAATTTAAGTTTGA
+
"'"*%%++$)#"&*&#!+&$)'!%)'%+(#&"%)()%)"&%'$')$"($+!%)+#$
@r3539
NGATGAACGAAGACGCCTGGTCGTTCAGGGTNGTCGGACT
+
&<!/&<BE<;1?.</8&>77.3'1E")&*#15H=G(/+%C
@r3540
GAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATT
+
C>G$;G1"+C4B-5(/5?A81?@,@#'"4.)()8?(<.9#,02C9<D9!9#.FD?@)457<(@;-:!!<9(-D/!F4>)/:C
@r3541
CAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCG
+
C3+"3@3@C2"1DC0:)*%/E'967#=40,5%"7%"+GD-*
@r3542
TAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGNGCATCAATA
+
DC'6E5)0#BG./2$)C=)(,H;=-G='&"F'!$/3:1'%2B707$6EF:%)9-+64E)35&#G<:"7*1&@>'017D8>(4+
@r3543
GATGTGAGAGCTGTCGAACAGGGGNATGATGCGTGGCACAAATTACGGCTCGGCGTC
+
7;@78%=%9E9?.3GH!9;<5,%@26<#)FB41+9)"FA7@'8D963/FHC79G,%@
@r3544
TGAAAGTACTGATGAACGGTGCGGTGATTTATGATCGCGCGGCGAACGAGGCGGTACAGGTGTTCTCC
+
-",=#-GF,@(-'D@368/:$<F@2!+H=4$952EA)%$*+=--6E+-E>?6!82H/6B=1<+2")%"
@r3545
ACCTGAAAATTTATCAAGCAGCAGAATCATCACNATGTTGGCT
+
$;1@@:D!EA23B8$4D6(%3C,E)&27."3@=111$6D#FCD
@r3546
CGTATGAGCACAAAAAAGNAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGA
+
:%H+'>+G!@E!9)7;4++$8,B5%38+D-F%7HB<76"@.!D4:<GE<7C<0#?A&BC='5B.C0,>>F,+)%1!H/9C%%D#1';494F884'*-#.:&@*-C!B
@r3547
CGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACC
+
/&;.E"G):9E-7-G<!G0D,$')B*:%../!1)8>;++(693!9:3&9C4G!7H<G,
@r3548
CTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTNC
+
#5+3G09*0"H#:C($+B7"G"'F>%<>"9=-#1$)=..3;+-7D2A&$=12G)?*8>D*5B=0@<:5D3:F:5C,.(/39G46DG1F3!
@r3549
CACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACG
+
"3BH/B"95@G.;11*>D2$0DG@?)E&172G=&'@=+>$*.DC3$=<A<A#668<6E
@r3550
ANNCCTGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGNTCATTAAATCGGAGTT
+
%"&$'!+*!)&())**'*&(!+$*#!)'&!%+)#'%"')+)$**"(!)*%+$)*%%+%*"*)!'(+#%))!)%&$%*)(+#))(!!*+'+#)*)&+)%+&"*)'*!))&('!%*#&+%$$$'('*""($)!%(&)"$(!#+**""&(!(!!#%#&'+'
@r3551
CCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGA
+
36-6:72<C,'/,!78'0,'A5-=D;E/)/A@=D1="@+%,A)C'(;3HE6/3:#9C%
@r3552
GAGTTGAGGTGCCGCAGCAGTTGTCCGGTAANGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGT
+
1$DB4CD.=-4%5;GC0C9>/,:HC9(*'2!-C+@:2:3$@.0.B@H$9FH"C8(D#0G!;G,F6A%H<')2D+E;<%&,*$)!C6&.A?>#D5D4?&-.1B2-(G&6,2=1)+6"8&63#)A"%56).4$%)
@r3553
GTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTG
+
E/%>,D&$86:2@=5C7'?+A,!.B@(#C6?-49*52)</48:&"6C?0.G2B$7C)"CD%,,?"D%:+E":&/@E9A!9<!96">0%AB,>,-
@r3554
AAGAGCTTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCNGTTNAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGC
+
)!+!!%&'*'%'*%"+&"$&!*+#&(*(%&()("'+)"$+$#(#'!)(!!($$(+&"+&!'$!)")&&+"%#*&")+#*#*'&&$("&&#+#"*$%")!&*#*#&&"$%""'$++%!$$()$"*
@r3555
TAAATAACAGAATNAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACG
+
<6!G7C.48+/>:>-9)="9'+#>-3&,F(G#CG!G,'-8>,"E3%:H-1%40#
@r3556
TGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGG
+
?<B801$&*$A41)H>(AA,./!%?(3+=;,85G"B9C,FE/F4+B-B3#1(##@9/D&82(>H2<2#2,:/%C:A3=/:$'E4/&:(.&$68C"D;=#+@%@G7>:@?<!'((/E0A>B"81-0")"AH/%)
@r3557
ANCGANGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGG
+
)$$+)#*$"$&+#&'$!(!$$"$)$"$%!+###&**$#!*$*($+##!$'&!%#'%"##*(*%%#+*%&&#(%"+)"#%!!"($'"%!)##$!*&&%#((+("("*#'+'"#')$('%(&$)!'&!(*%#)"+!)(!!$$%"(('")''$&+#)!'#)()&!$&(&!+%+(&+%')$#+%"&'*'%'((!#$++%('%$()
@r3558
CAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGNCCGCCGCAGAGTGGATGTTTGACATGGTGAAGA
+
++*)&('%#&%)*($+(()%)%"((&#++!$!+!+)+)$"#"+#$!%(&#)%)!!##''+$()#%!$$!*')!("
@r3559
CCAACGACATGAACTGCAGTGCAGGTNAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACNCCATNGGCGTCATGAT
+
&,*&&9(%8D-B@57(%)=->H):'AB5!%1#DH'G);"B4230;6*/.;83GA'8=5>%!BC+9$HG=@!,7/8F2%$)G1!8&-@&#&C9;,E&/4=$
@r3560
TTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAANCTTTAAGTCTT
+
B2>@;9:"*/27&1!1DC5G7HB@637"B2:-3.:.E34;C(&!&8G3B@@-+9HC?H?8>)(+:;'70)-6"1$$?H0'?A!!D&=..+8F*#@B8#+0D77C7%B21&)F&,=/=(2@:=ACE@<!>>83>G!991@.&!)#A0G(4,*",:!8&/F@*F++'=A-@B'"F*)2EC2$;
@r3561
CANNACTCGCNATGNACGTTTNCNCCTGCTNNATCACNACATAATGCAGGNCTTCACGCTT
+
))%&(*&))(*')"%*&'%&%!"'%(&'$&*+&")*&$$$()%(*"+"#%%+$)%%#"""'
@r3562
GCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCANTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAAGCGCTCCTGATACGTA
+
(!9<@2?,A2+';%'3/G5EA(;0#.ED@D&E24&.=D-/+:9D5E+0CH#'*&:,8G)>B&5@!7G4E*+/B20=E$:11:8<=-/?:B)'@H1G15%=$AEF%A3D/!D$C?>;H;*0%#5=0155<EBHD57*@.&!0&E@-BG.@&=<=4$3D"F!=<!$#&$50?*:;7
@r3563
AGAAATGCATTCCATGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCANTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGA
+
)!&+*!%#)"")'+")$(+")(%')%$(($&**&!$)%*##*"(*+$%$&(&&'*')'+++$(%)%"+"+"$('''#""+%*'%$()&+%)#++%**'$#%'
@r3564
TGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTG
+
G<2$:%2(F3(E"1A$?3--HFG8<;*D?!C?*7"5'GE&A?0CB8<@*)25*B>H+E'<?%C26+)A>@':'1C?G7G2<
@r3565
GGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACNCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCG
+
&)7#;,'#()8*A:@A.@*8*@,.FB)08&=+B,F.;H)0"H#3%*E*FE%E>81C(09(@-F02.C;#FE:&6&A)47/#@!E)->/<A6BC-8@*6A)2@D2C:)(9@9<C@BHE8&F.=*3E3/B-8/:<?)8D#:4#
@r3566
CCACTGCTTCGCAGGCTGACGTTACAGACGTNGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAANACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGC
+
A3**G5*0?B-C80"!&F8011$,$*/",B/(96;34'2D-59!4/,'6*(.%1G+(*6-7)#25*,C*"+;6$25@D:>69'#!96&9@"5D;=&00/6E4?;#?:$1C86&?A06#)B%$F7:635.:B%/2&3CAF00B''*G8+961
@r3567
TGTTTGTGTCCNGAAAATAACTCAATGTTGGCCTGTATAGCTTC
+
.B&$!#(G"G26",%@"3DG!&A-(31':$4@!HC/C';!%%")
@r3568
TGCCAAGGATAATATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGANATTTTAACAGAACATTATCTATCAGNAAAAGGCC
+
,=84*G*$E<+*1&BH<HH@>@5!;"E)')#-'+-B;%)B9:19*3)G&B29E@'7H5??(&&?+8B4<%.7%&<0.')HD=)5@"0,'GB-A?%,"%8=8D=FE,B;0/
@r3569
TACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCNGCAATACGGTGAGCGGTATAT
+
C?#2!,A)(<52-2E91D/1AGB3!'EF';&1A)*)<A=01,D#15,=B-22<)"'@+3-(292"54,
@r3570
TTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCGCCGCCTGAACCACC
+
80';D%;7H6G06%"'0%83H&+3B3$E//H@5)F,@@;/'6@5/=D<'"86B;.>!2-E#&5;4E93C06-A(,7!5=A.*;7>'6*G46+B<H)F&"/.$/19"!7%((,2$@9?6C+#,"?5
@r3571
CCCATTTCTGATCCTATTCAAAAGGACACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTT
+
@*>F%@@C.%,&;'89)$(H$11&497>D?80DH%@0*,=F"H9==E5D(/H"$;:'>@-/>07<*2B.&!=F*51@<4=C))?>$+'
@r3572
TGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCG
+
-823$%5(06D6GA(FAD"$B7-/C5':A)#-'-C<:0G!?*GG'0<"71>&E'981",4""
@r3573
GGGGNTGGGGCAGTCAGGCGTTGGTGCTTNATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCNCTTAGAAGTNAGTATGAGTA
+
('%'&+'$#'(&#'(!'%#"'(*&#$)&#)('&"#+("#!$%*!!**"(*&+"*"&+!%+**&(%(#"''#"+#!+$&&)"*"$'')!("(")"')$%!(*!))$'(!)%$!$#)"##'$("("#+*!+#&))&+&$$")"$+!))+$+!#"&$&)"$'&""*$+&''"%*'&')$*&%!%"&')#$!%
@r3574
TGTCTGCACAGAAAGCGGGGATTTCCGTCNGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTC
+
DH!;E.)-08'22'B#1">8DA-4=-D59?:F=6B"$FE2+6<D:17E#6%9>$6?"7:B@2H7&<33;H=
@r3575
AGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTT
+
(B#@:;+,E'E>/7%&D6@@#<D@BF2'8!A!F/E<!B)=%F@A2H((>HA6<;4)*E"';?7'EF0E30.!>=A99A(9A>6C'?"2@/4!<6/$64!E=G?@3EH'-/C0+4,"@'>1'5B$=$$2,3**AF3-E!'H=*D75%-?./*?,'(
@r3576
GCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAA
+
*='#(1$#*CE06$#9&+-7';1$=GD/DA<@33<#5@+@A:F#<.69,'7>7D5?D8#F3*CG+;4'
@r3577
GTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTG
+
+-5>#&11G!'/+=2$=)DD1C&);'/9(C-366"-6/:(DH<!"E=3AH48@)+9!D-81$
@r3578
NGTGTNNAAAAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGC
+
!)&'"!##$#+%(%%&'')!"*%)%*##))!%$*"$&'+!")(%)!&))'!**(%!#"%"
@r3579
CTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCNGCAGCAAGTGGGGGACAGCANAAGACCTG
+
DCG&!&!>0($-;?=46<AB;=1#CDG0$$8".?:&0D,$'&+#%#B(:)@'9+07D,2E:2?05E-5'-$.5G8F46A@)@(F+>
@r3580
TCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTNCTTGTTCGTAACTTCGATTTT
+
AA??E74CD65+1/(FDGH:HB227#%7*9!2A$&&54(C1?./G9%ED@)!!713/#**+$&6!0=38=A4,:H,9CF(C#65'1:.140:*EB8'.%0)4+/7%7/:%%,&(4&/H!0?,#7#F/D+"'8E,+3H1)&DF2FH?)1=./
@r3581
GCCATTGCCCGCGCCGATGAAACGANACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGT
+
&<)9F&E9@($-'G9#FG5@$7E.<5;'$7*2!;>.&!BF-6A":$;(9$56D$0:H/%.C.G@:8(+@!#B,=3BG;
@r3582
GGGGCCGCGGGTGCTCACGNCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTNCAGGAAGTTTAGCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCNACAGTCAATCATTGTCCGGTACAGCCGTGAG
+
+%!*&#+#&')+%%)$'&%""*#&&'&%#)*%+&'"'#!'&()#&')%%%($+&%%''(!&+!'&*$+%!+&+)+$(!'!&)%''*("&!(!))$!&")&#$'"$$%#"("%!)*!*"&*#'(*"+*)+*'$+%)%!(&'!%*$"(**"*%""%%+*)($!!"!#!(!')'%$##$&#*+(*$+&!+!%+#
@r3583
GGGCAGACAGGACTGCGNGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGNCN
+
98$E"*:&)*+@A64%7+=6<9+(;(+HEE#>(!+3,C;9==GB1.%4A85H*@2@A5A)9)-=
@r3584
CAGGGAGTCGATACCGGCGGTCAGGTAAGTCACACGGTCAGGAACGGGCGCTGAATA
+
B%H(>FG$F8E1,+$AF%6EB0G-8C)>"(@G&,,BEHE8;5(<E2D:A1)C*./D,
@r3585
GATAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGC
+
EF0,.&=4'(?FFC3A*E&;E380=!<9*($C.($,5C?3>"940(4D6-F/%@0;/G*41<;F7
@r3586
NTGCAAGCCTCACAATATAGTTAAATGNAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACG
+
#E(D34-.6@G&E3$,9E;*<*33*E-&C3,;H5.*F$;$)#D):B!"G<;.6?0%/654C/+.#3A87<F
@r3587
GCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAA
+
5DA/#D!0-;2+3B--6'B)1-C>2B8'0C6>957HD93,F,(509E>G5A&>H$:B88/!0*9E#04#'(?54>6!CH*??5.3D?'$%)8+C*!C(D;F
@r3588
TGATAAGTGGAATGCCATGTGGGCTGTCAANATTGAGCAGACCAAAGACGG
+
2?8!0-%AA27,6<4E*=&"<37FE3-1*&6"@$)8=>97B"B@$(7F%%+
@r3589
GAGTTCAGACGTATCCAGAATCGCGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTG
+
"6(5%">C1G="B<F6.@:>:)9D;1)6!H=9"C(-;=>&@C3>$=,4:D&?-"@668?&%-*"4$.2660F?,<2*%19,0)16$40$-3=<%=2((9
@r3590
TCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATT
+
$D:.))7=#E%D6(A3?1,E<!>#4.)'&64%92(26.,*-/%"H2=9B=,/6,41)$<GBA?8<4=4!7$+CH&+.#2-<B@>18>G='""42
@r3591
NNCACAGCCCAGCTGCAGAACAAAACGCTCTGGTAGTCATACACTGAAATCATCGATGTGAAACAGTGCTNCCNGAACACGGCACTGGTCGGCGTGCAGGTNGACTCGGAGCAGTTCGGCAGCCAGCAG
+
"#%+#&($+*+&"(&&%(%&&'$*'+!#'&$'!"%$$%+!!&!"!%%&%)!$#%)))(##%(!&))%*(("'!!+&#!$%+#)&*%))&$+%&#*!)"%)'#)!()%!)%"'$#%!&#*+")#"$%+*$
@r3592
AGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCNGCT
+
=C1@#&5!2@=1(5>;$?8BB$.<AH%AB%AHF-)*:8?35?6HE0#
@r3593
GGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTNAATGCGAACTCCGGGACGCTCAG
+
;("-(@&;;;/<%8D'6D?-5B6>)?&@5:2//H'"?GB3>9$A(%4/!=+@"21)285B009FH/7):&)+,:,$&8=!2-EH-:@
@r3594
GGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCC
+
H<$+/C:'/="B.F#H*22E*8@4(1D54;G20C&-5?3D0A9+#;
@r3595
TCACTGAATCCGGGAGCACTTTTTCTATTAAATNAAAAGTGGAAATCTGACAATTCTGGCAAACCATTAAACACACGTGCGAACTGTCCATGTATTTCTGAAAGAGTTACCCCNCTAAGTAATGAGGTNTTAAGGACGCTTTCATTTTCAATGTC
+
D*%4)0+0,)F+77D%":=FDH7,$1%5*)>%FF8"<0,F!=9?8*0E(=/3E,!8@08221+4@+1D,/DE+%)4@C6E)%C,>">/+=?;4<0,#&(*39%CE'(D1:)&011&4'@?$29&*;<>(G122;12D"C.C4B?7G2DC9B14EE
@r3596
ATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGAGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCNG
+
0*.7=@4:&1A"8E>?1)#>C+GE+5$/1#B>G72<9"9;4B8&C#CG!%F$*(B21<41A"+B.,1&13AA-%859-!$.H*?;9,:<30HHF%/
@r3597
ACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGNTAAATAAAGATGACCATCTACATTACT
+
AE/G)+C'&3=&+<(3?F8%>5=$$!)9D8.0-02$1:0<CE58(!A+A/14'86F%+"47!)"!)!D&:;1E-B"6:F0!$/;54/"#''
@r3598
CTNCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATNGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGC
+
B9"/2<8*7=ED/01/'?,G+34>EF+"2$8'6H,D4:#D''E26B">==,?E#*";8E#,8G<3?0G%5:A7===E<."2%<A?3,!)(@,9%
@r3599
CAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCNTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCNCATCNTCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGNTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGC
+
@;9=7(D6/A54B3.8'/5;:GD?:$<7H4"'/'7,!26?,.57!2GA%5+8*54GD1:$?!H*)#+0<7'6D2*D<%7':!),&&?8'H>:8":B&6H=F$4=C:1?#BE0:7*--2<-)2>;7<>+HB)#%1H&.G?0=:822B/#?2!H1,A;E;D+F3D.2+!54)*F)+A*7G?';+?.,G.;4F"#!A0::2(.,=5!1!
@r3600
CGATCNCGTTTTGTGAGTTGCTGATNCGTTCGCTGTTCCAGATTACCTGCTN
+
61F"7.34(46>8G4#%:ECEB$/F</?!:#?9"'*E5G,CE4D"8:F8&#7
@r3601
GATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCTTGANAGGAAGTTGTTTTNCTGGTTCAGGGATCGCCTCNCCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACT
+
DH4%(2>DGD.,;$4C0A116$"G%$#,@F6$BHF8#5D*,".8DD*&.1&H:,5>%+7&<6%D=F>31:=;!2A71?7A/>*A9C3*H*BA*>1=;=:ECA*#A(DH.B47!1/2+*!<H6F#?=@G:150@*1/A?>#@;G9:(EB!&$&6.'C$&0?BC8)%<$H/>2?4;:C;7$:4-*#6&,5!G2,B#4@358#-H00B=2/CF;':*+<)2/241'A,6"(318<,4#&1+*257)#)F+:<$0!$G383?D64"75<B0G
@r3602
GGATCCGGGAGGCGGAAGAAACAAANAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGNAACCTCGTTGCTGGAAGCCTGGAAGAAG
+
C7H=>4/(G7<>+9B8"%!<B!A@9/'60!-)@7:/7,8.9>,?G4;FGA2>CH/2?)@7)0H8&!2#*5(4-$1'<E:C2#C7G3<;A7,$62"C#C#H2HHGC#A31?/@45&1E"!=+$F8>27&$0;?@+
@r3603
TNGCTANNAGCNNTNNCNNTGCGNNANCGCNGNCCNNNNGGACNNNCNNANCAAAANACNNNNNNNTCAN
+
$!#!####!!#"##!"!##!#$"!!!!#"!!$!!$!$$$#!$$##"$#!!##!$"#$#$$$$!!!$!#""
@r3604
NCGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCAC
+
''>#E-29HG;11/,;C"#"7*C6-9@+C1(0)%%A%"&="31F86"=(1?6$
@r3605
TAAGCAAATTGTCATTTAGAATGATACAATATGACAATAAAATA
+
+306$AB@;!"'&B<*%)2&3969/'':-4*3BE.!?-7<;H4D
@r3606
TGCCGGACGGCTTTGGCGCCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGNGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGAT
+
#++#(()*#$+#"$"&(&+(%*)!(+(%#''(''(($(("!*'$%$((%%'#"$"'"'(#$*+($%'&#%+!))))#&!%##*!*!"$&(+)$*#+(#*#!##"#%$"#'%$%($!!)))$("!!!&("($!&&('''#('**!'*+(+)#*'&&%'$&$&')')+'##*$"*"&()!&"&'&#%$)%!&)%&*&$!)*)%#&)(#%"(
@r3607
ATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCA
+
&/58,,C.*$"-<'5)*0-:$D#D*E!&C-%<$"/-.!0-8C<'H='=&=%;?$H.0)#(2/1>&&G>F;,?2<8(<&%>)%A$*309#<.FB7C
@r3608
CACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAACCCAAGCTTTCCTGAC
+
0&98!G012D&6((($.!!0(4G)@HB?4#00H&D+H;!*2,1E*BA11!=H"HD86!DH)9/A>,6+)8>H0'2&60D1++AE2BD-91+0F
@r3609
AANTCCTACGGTCAAGAGAAGCAATAANNATTATCCGTCCGGATATTG
+
E&5;(.A<&>-!#"/AB2H)G")-6&C:-8/*:8-0B$,%@"*2>93*
@r3610
NGNTCGTGNTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGC
+
%$&#"++$%&&"("&$*+$%*)(*+(%**%)%($"*%)'#'$($&$#$*&#(!*#+(!&$&$
@r3611
ATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTNTTTTG
+
6208:BH/"(?C20B1G1D!=.0%10,6744#",18A'!(FD6"0=<6<F-
@r3612
GGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACG
+
:/(0:'"=1#"#G%4H(%:D%!/*+B:@:.'&55H0$1+!5/""E
@r3613
GCCNGTTATCTGGGCTTAAAAGCANAAGTCCAACCCAGATAAC
+
$*&$*++#+$(&&%"!#!#$+))))%&$'"#(+#(*)#&&*(+
@r3614
TCTGTGGTNGATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGCTGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGNTACATCAGGAATATTTGATTCAGATGATATGACTAT
+
&*$&(!&*$+)!&$%!(+(*"))+&"!"'+&%#''$*(%!&*$+&'#)*))'"!("')!')(*!"%)&))!%*)$*&)$*$)"+(+)+%%&+()(+%(*%#'+!$"&"##&''&()'"'&')%(!'#"(())%*%%+("(!)#&((%&)!#*"(')('$*(%&)(+('"!*$*+&"%($&*%(%%&(+%#+%+%$)"*)")""#$!'#%
@r3615
ACANCGNNCGCCCAGAATANAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACANATTTGGACCGCGAGTCTGCCCGTCCTCCACGGGTTCAA
+
%'"!'&"+#)&&#)#'$$"&&&&+'!!+'#*)+$&)'+%*$*++!!*'%(!*!&!+!""%*)$$*#'&!*!")*'+$'#$'#)!!)$%)+*'")$($()+!$$"'!*&"%!+()!'*"(+$#%$$($#!#!))"#%'!'$+(+#%$"&%%(*&(#!*'$!'&%*+"%"!$'+)%$)'+!!($&%'#)($!%
@r3616
GGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAG
+
*H7'&;A8$,<D8'4<0:G1'=.1?+BHGF#=/02#0A?58
@r3617
TGTATNNNNCAACGCATAACCCTGTAAGATTATGCAATGCGCTTTGGGCAAACCAAGANAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAA
+
)((''"!&!+%"$+)*")%%++)+*%$!+#(($'&$%!!)$(('$!&*%$+&"#&#!'**')*#''%)#(#'"*'$%"!%$)"%&#!&$)*&+'+%)#
@r3618
AANCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGTTTAAGCCTGANGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAAT
+
'6F1"=9>90D$51-6F,BB69)CC&E98/1-/+=$5F0,00<!8C47;(7&?$!5.>F->1>8@:D#1F@183CD;#(>-?==G0"@@3HE8<6G1&;)5
@r3619
AGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAA
+
'>?#.GD"/&BA@D+,=%+#;89HF'>..8,-(>?64<CH+7')%#B!*!*!&9GE;"8@>E?2-;<A6$;#+@9!9,0=*<#//'F6A/"==%#4CA?EG">@1%2C4G33GECD9FB"!/;'E+')%E!?H1=>)+HEFH;31)D%+E0C*(6HE!89GB9
@r3620
AACAACCGGNTGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCG
+
:D71A42A8'#+90#.3>07'=,*#9F)C=&G6A:30595<>0C0;)+4F'28+:;/,#(=;((>)'@?:
@r3621
GCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACNCAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCGACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCCGGTAGCGGAGATCATCAACGGNGTGTT
+
2(=847#;3H38=8-%)7"6=.)))DDB-4E6*C:H5!,>%2E*+<,13H0#E?0$G?862!A;>GB6.:/0E'A3'EBF8<*,!!,0&'==';$1=AE<55;0(.+&A<G0*<9!!2=>:'0%4#@#,,-3ED#>0:+!)A?04G'DFE6?A<>7-'F@!#C8/5678>F,%F@"2<8&++C%@<;6CG%@C@G46$/"F1*2*=
@r3622
TAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACANACGTTTTCCATCTAAAAATNAGTAGTATTGAACTTAACGGGG
+
5>:6>5ABB=*%C5E3,7:3*-4/$#-.=1A#/,3$,6,15;>C'067HH-BE,>3#&7>F$',))9*!H$;=->(!)3<<A8)B@#+>2H(79!'*1>0F6
@r3623
CCTGAGGNCCTNNTNTCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGNCCTGTTGCCCAAGTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGT
+
)""#!&*%)(%"$*'%(&++"++""'*"'+'(!!"+&!(")!)+)%')#!$!)(&++$%)(')$!$%'(#('+$+*+&+%'%")!*&+)&)("'&+#!$#%*$$'!"+!&'!%$!*(#$+)&!)$#)$%%((!%&!($"$%)$%#+*&))+!%)"')'!)!+%+$#(**&*'+&$)&*%$*)%"!")##+#+'*(')')++'&&((#+&*++%))!*
@r3624
NNGGTNNNTCANCTNNNAGCNNANTGANANNCNANANGGNATCGTCGNTCNTNGNCCNGNGNCNNNNCGCNNANGNNTGNNNNGTNNNNNGCNNNNGCGTNNNCCNGANNNGNTANGCCTGAANCAAANGGANNNNCCANCNANCNANANN
+
!#"$$"$""#$#""!$!##$#$#!!#$"##!$!$!"$#!#""$!!"!"#!"#$!#$$$"#$!$"!!!"$$"!#""!!#!!!###"!"#!!!$$"!"!###"#!"$#!$""#$!#!!"$##"#$!$!##!$"#"!"""$#!"$$"##$""#!
@r3625
ATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTANAACCTATGGGTGGAATAAACCAAT
+
,/A>G;2.A=>9.)2)48$->$B(87,=8=E%""FFH64AG248C+*>>*84+"D5>#@2<@"EGE'FB1<'E.D9+&D0DG/>E(1B/"H9/$/AEH
@r3626
AATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGC
+
BG@F(9'@>$D!?*@6*)=E@7*<$;5-@')%.7/AC1)4@FC=;>%#D?#$")'2B:FD$"%56)*;B1!;8(1F!&/"?&5*F9@F$<H-B$BA4'>$*3?+!%C?662E,#-;"@/&736+E$(55(0"E+5,4;D<E--.%!=3&+;+,2#FB,9>14*2
@r3627
TCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTGAAACCGGCNTACAGCAACA
+
D78AEC.>,0@3,/3(A:&E+,"6G-%DF-!2<2:*;9=C46-4.6ECH.7D.$:9*C-1+6GE2D3)/B#B:
@r3628
ACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTNCCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTG
+
)B3B%<"7)D-A2H=#%+>*5?E$.:1!8?#EGA.@"<!G*.G!,$#*>+$5)-"(+!#%6@5*)5>$>):6A"GD.2$0/86+<H!DD9C=:.#'->/-8:2!(B-:>."F<(6+90,5+93#DD/>00B&(/%G9<3A
@r3629
GTTCGACTGGAATGTTGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATNCATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGT
+
E@A4EA@--A?@(G4:*?3@FF,?43%?:D$->F.=3&('H(8)#6"5!*$7<1E%&'98+179&%3/%!F9625H&"#&6)5<6(%4!'?:05$9)/?B-A0.:B=?=2-;)?=">&80!.BDD?654$3,
@r3630
AGAAAGCGTGACGGTCACACCGTTNTGTTCAAATGATTCGGTTTACAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGC
+
-"G=3"GEA:H8C-C0.>1:<769')C7!8'HH>H60->@?"2"DF%1H$@D5,+*"80-@2"-$>#2!+F4=+>6::6;&;4F69EH30D9-:(D:EB3+2
@r3631
CGCATTCTTCGGTTGTTTACCCGCAANCGCNTTAGTCATGGTGGTAGCAAAATCTGGATCATTC
+
1A825@1,?25&3%DF:<?5<):*GD>=9+=;C"#6&$85'C:A-!;&=*C;=>0/64>&*<3'
@r3632
AAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCAT
+
9@.?>*(-$.-("@H/9+3:$(?/+*989H*'>A!;2C:(@4@65F0)E3789127.4'0+04%,54//F$?/=!6#6)%6G*=)%F98?=+-B#;?1$2H+,'&<C0H76FF=>C#9'+-">3H,<C8$#,6)8#>%@6=E'B"1!3
@r3633
NGCAGCCGTTCGTAAGNCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCNCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGGTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGC
+
!5?3)?8D=';H->*1*@G(?+$,.+32:9?F>G8(C7"A:&<)*)B*2')G'?=;"1.#8))")(-98B#BD"02)(9=,=<);:>;F$"D@63.5/8.9C;.9"!C<=E:7BEB+73":&8AF6D;GD+!$D<AE7*ED<.$8'D;8#H!$<D0C?4)A:?6@A,;E(00-
@r3634
GCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCANGGATGGCAACATA
+
5E)>,,2.2"G8#&$8$)7A1A@9(07H7$&2,;F<F,D*CBC",D(-/D5.>'&B=(&8B
@r3635
CGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGG
+
&>E-$"!@*0,G1$H$$C+1C5E+:(82="38?>,.('A'.95(BA7!5A@B$>3:$3#/#"'+D<5!,D/D24%:;6H;&25:&/$3<.8
@r3636
NTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGNCATGGTGTATTTGCCCTTAAGGANGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGNTGATGCGACGGCGGCGGTAAGCNGGGTCCGCCAGATTCTCCGGNTATCTTCATCCGGCAGGNGACGCAGGGTCATCTGCGGATTCACNTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAG
+
'"(:'5/"7*E":;6;BB&FD0H$"H,F#,"BD:H)$H2*&*)59-/!,-3&07F:'>!;#!"('C<44!C(:+)++$"2$<(B9E$F"'8E/52D-/29?:,5F797@10F;H:7'/<3++65,/F)C7(F-/C@CC91B?.F#;67#;5546*1G?/7"838E1<8A#"D>&5"CF8H@15">:+H3)H#%!@8'27/&-=G!'"?18#4"3-;/D/5%#%2$DC+A)6<9A0'&!97CF8"'B2)8A!H-)346<3)-5?'0->5%!;A+)5
@r3637
ATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATG
+
C<@F460B(D9D<GGA='43BC?5H,%06:E>F*$5.-"#*+EE:<18+B+AB&"C?4">?64!B)4E8&.A00$+<5H1$;/CD!:"!(3825
@r3638
TNTAACTGATGTAACNCTCTTGGCATACAAATAAACANGCCAATGGGTGACGATGTGATTTCGCCAACATCA
+
"&#%"+('&+%'*)$&&$)#%''%+%!!$+'+'#!$)!*$$!!!*&+#)+&'+$!(+)+#)*!!#()"+"!*
@r3639
ATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATA
+
4*(:+/1<!</:%*E1BA#.&>*#FF>7B:C!0-%#@2E:CE
@r3640
AGACNAATGCCAGGTCATCTGAAACAGCAGCGGAACGNAGCGCCTCTGCCGCGGCAGA
+
*-,A)<.4@$(,/&D6DC!-;2D'<<9'>8)F-HB,EC:F%0B?900/5""@F*;,7,
@r3641
GNCTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTA
+
!!*E)7/7AC3+:/E3)30:)*(0&,D?=6=>3C#;@:@0>-D<-*A
@r3642
CGACTTCCCGACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAA
+
)FA&*9C$6@B%5,04C4G$1<>C3"?)?=?AB)@---G?F<D)H#:*%B*"#!-BH=5,@615-B-?8)6!8*54"*>C/,5$?F:2'#
@r3643
CAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATA
+
30"<ECC;!:39+<;:B>G+*<40,@-)@@D+.?675F4'7/+FA;69#+2E<6D7,6%-0F05*,#<&"7$&7!/E4-(;*&;8H0=!)D#!-%=>&<7!&&&A#F3026%@1(B2@,./:H$+3+B:DG):=
@r3644
TCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGANGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGG
+
48:!<%7:(*8C:$)8+4-F:$,1>&)&@-A3"((CG81-F5))+->)@'/)G=A"#22+)A"36&%)!-?A(F!55*%0.<>'<6(?!E:;/F"8/./=()':59((=+1D<G&5<2"-6$B3,<:HC:11;1$6.?E036%+>?&5()3"#12HB9+):09.5-
@r3645
TAGAGNNGAGGCTGANGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGNTTTTTGATAGCTT
+
'%#')&$+*'()%"!*$&!*!")#"&!&&%"+(#"+&*#!+%)(*#''()#+!++&((++%#(%+'
@r3646
GGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAG
+
G5D'-DDH5<81B>A$G!!.#)9C22C68&A)'+<;1D=,:+8
@r3647
CNAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCC
+
"%.?D(C:!@>!/C"%$''C0H;#*70EA,'0*.9?F8;!@/&"=>37-5/1@47)
@r3648
GNGTACCCTGTTTNTTCTCATGTTCAGGCAGGGATNTTCTCACCTGCGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAG
+
(!D&G=A#&F'>71#D>$(69$-;9?#!0A<;-!));761/''?.7#8C8#%D/D1F/=")A'@7$.:-@9167H7G>G"F)+CG#E/B:-F-5)$,ED4%&25%#/
@r3649
TACAAAACCGATCTCNCTCTCCTTTNATGCGAATGCCAGCGTCAGACATCATATGC
+
*FC/5$%"#=889("71=4FE$?*EA<,EFF*.=-+22@%>/*!<,7.>A,F351+
@r3650
TTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCG
+
8'&D;B9).-(?8<BF7>>*%C0!D@C<,'D7):5H-".-?
@r3651
CGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGT
+
99):F2F+AAF&.?-<#081%-'F1>=!5%<=!BD/@/C:(,F@!B0@5##"H408="'GF&7>>
@r3652
GTCATGCTTCTCCAGTGCATCCAGTACGGCTGCNCGGAGTTCAGTATGTTTCATCGCTTTATTACCA
+
@0*:-)<,E4#'0E%)!2A,D&@@!#'925"0"#+#'((F7.#.5@<,D32C9G33?-!+-?/E8F.
@r3653
ATATCCTGCATTCCCGAACCCAGCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTC
+
;2):#F"(F%%,<."!F"@'H8.<%@#01%27B3A:/65E7@G@"<1.FHF$"!=>#BE'H-ABD.DHF055@'*6B1DGB=B?37!$4!;/F',E/1FA,0
@r3654
TCCTTTTGATGGCCAGATAGTGGTGCTTCCGCNGACGTTTCGCGGAAGTAAGCGTACT
+
><F=,EC'.1-06@(*3!!42>A:@/8<8?%@:E6(=##E/":.:7&0G>6";3!H)3
@r3655
GATGAGTACAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATG
+
$D(7-+A:?33.%6-:1B6D/B,$)7">.%@/C!=+CF)"EH?<1()H"%(G*
@r3656
TACAAANACAGTAATCGACGCAACNATGTGCGCCATTATCGCCTGGTTCATTCGTGAC
+
&%)(()*+'!!%#$$"#'#%&'#%($#)#"'+($++)%&#'*+*'$()$((&('$'%&
@r3657
AGTGTTAATCTCCGGCATGGTTTCATCGTTAACCGGAGTGATGTCCCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCANCCTTGTCATAGATACCAGNAAATC
+
(1;C82.H$/#9<:45D;40''1C"%.E6(8#8G$**=.$8)(?2';3)1@A.&"BA'#$'#?$.!8C+<'1E+@*+C*C3>?26+E1=9"BA/F?E=5?BA0=:=7E,3G#.7.)%3?2'!+BBH6A
@r3658
TGNAGNGNTCTGCGNTGAGNNGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCG
+
''&$)&*#%&')%%($"&"""+)#+&'')&%)&+"($"%!'*#%")'"%+%"&+!*$#!#)$#*%
@r3659
AGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATNCTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATNACGNTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCA
+
C3D!2(@=C83);<5&B$.(G$#"2&58>:0.$>:1'@*)E54A#EHH8D%:2!H32A*)-%.6>'A=%*D&>%"90>!G<?/&694E5#?%=5%"&;<%386((.D:*,#'D)($56*<;66;&,(1)?4*3D;#A9D1.88B>*3=/7$#.5:A.=A+17B3H35#32AB=5#3>$6EE:F*,3:A*.3%,ACG,&DE2##,D;H<.D?G)B5>+<)&H03(G2.=%:#.DA:&>>H$")86:E;$GC61E(F0!.=$GH9,8=D@;?#5,B+31$;E!(3F>.#&4*B4D%'D"
@r3660
ACTAGAAAAGCTTTATGAAAATANTCTCAGAGATAAAAACNAACCCGCTAGAACATATTACGNTGACA
+
)!:D2AEHH1D8F>.+395!!74/:0.#D%H(&F%)B&74<%0:-E08C#-"?==HCA(7G8-;5&5(
@r3661
AAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAANATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGNCTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACC
+
E*3F*#DE725A3G.#5H5-&H38H0,&"!$=0G2H/-79!H.,">3".*'&+!=)A'-7<$5/+$%#6>7!3?$+=G$4:74E?$2D@"9=A!;'.F)ABBCA?B96+&<>$/@?:F-%1</9#?E02*2E?>6'<>&3BD(.%'5&0-14G.##-E5#543#A0$'%A:*2'#-%%2?"0%/."E1-35+22$@2=/#HB.#)%4?D&H72*
@r3662
NGCGCGGTTGCGGTATGAGCTGNGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTNTTTGCT
+
+&+"*%'*&#$##*'+#+#)%*!$')'&"*"#$%+#*+")$!((!#%(#*(($)'')++'*#+)'#&)
@r3663
CTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGATTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGT
+
A'&"9081$:F",!0!?,5+DE).%DC..A614*94)78@-7!!6#C7$?9G05E-"*/.&*>+;>7&FE?:&44=04<;H"F4'D(H8,".</,5D;@"6D&-73,CAE'D/1<"1
@r3664
TTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGNCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGG
+
"#($/7C$GH)4C3!$4D;C$$**B;D6$F"#2FE-6(++,<3F9?,'A*<E-%''&H'&')4A?D7*)&,6?!GA)(!H43>D/=&?$556#F)&>3#)$)=H'%,,A643#4:/@@@?1<ED;.9@5+.G-%%1DD;4G:)#.G)/*A?9:!B<B&CDG8C+C<4:F:19&G'#,DE6(61)1HD,E55DG4*EED*@A1FF)&>21$@-7<=.3:<,04472>FE<-G'0"=A5'*C"?B%-(,9,552,F4+3E$"#7)!?
@r3665
GTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCNATATCGGAAATGT
+
+"49,4F*.3$:!%)"C",*"8(&*0A//77(!C*@2H84A!><#CA67+0?=H8>D69F57%(</=<,&;/?,999%+=!,)FGA?;68(3*!25!:E-E,HE>E.<F)+=F/%<!&)99@3D*D<#8
@r3666
NCNCNTGCCATCCAACCATTTTTCGACCTGCTCTNCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGC
+
"#''%+)(+'&(($!+*'*&)#!)%(%(&%(&'&'*'##&)('+#*"!')+'&"++&*+&*+!&%#*+'(#%"+&%+(*!#&'(%)*)'*#%$''+"+!"+)')'%!*+
@r3667
CTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACA
+
&4D<F*235B99=6(,G9<*=0-"$6-#')7+/9178G4?$8C:B72G(5$/%H+'7A)-+>.!/-;<G1%0C#C%G3/.
@r3668
TTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGAT
+
(E=D5E.A=H<H*!2D4EG=+%F>>/!!&&/D0.?F<F!$240"
@r3669
AGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTA
+
4%E)!-BB%89262548G5#7+C2/@!94$&H)4>#E2%30B/D>+)<E!2A.780F30@8-6?.&/"74?>5'HE?!"E;5*8F9:@)'=(=/G?*>/@#D"25BF=<1=-H
@r3670
AGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATANAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGA
+
8D:/&$C'>/FB&$-D9#'?,%-28-.A2>D34DF)#-GE2'8F!1+,@$,@+(8&.-G$#99*()!477B'>,H83$1<2.G>AC,6?0?*A<!!)A4FF@/:>,&"+;+2G,<%&9#H@C;#H2!&!,H",,%BCBG=C,5<'%DFG!H(7''&,9H(-'+BF4*3CE9"(4,!=/(-'8D.;,"E!?":"=>D5%:A$$@%%$@G-(,7.,4:B3AC/**88)>&/AE"@'3!<G(569C0(07=?.5,,((%;@1%=G&,<;@CFGD?6--;=*#)43'.:!-.8<
@r3671
GACTGCGCTGACATCATCGCCCGTGNGCGTGACATAAAACC
+
4$'(#"311HB4).<'BA+/"C!79=/E$G0C5?)+G8A7+
@r3672
AGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGTTT
+
=)C%%9'38C&?C927<1#,$(&9>*2522+%2-)20E:F-CG.746$;B*HBF+
@r3673
CAAAACCAATTTTAACATTTCCGATATNGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATCCCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTTATTTTATTAAAATA
+
/*H;#0H':"40<.+>/.C$="$,;6)017E%)F2"B#E0-*D:/,0#G&$3A<F#,G,C>9'8@;0G:8160C:+:"-C+742;6?1G=).6:EGE2$CB#.C,-B3FE0@>1'./3H(3@3!"D5'A-6$+:==&,G-+6/*)'.'&HDB,*><&/C?<G#F3*"G$0*658&?!/'1=#4+!!-C-.>#%4?1>?9(/*
@r3674
CCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGNAAATTTNGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATG
+
5':4=1G4(*+*@G@-7<@*D946A+G&?*8)>'%F3)2#*@81HE1%&##5A-C)!HHC%4>F(E2-27".0:DC3#>97D;4170?&:;0B?
@r3675
NGCANNCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGNGTTCAGCCATGAACGCTTATTACATTCAGGATCGTC
+
%*((*%%"++%'%#$%!*(!)+$((*#%!"&)#"#%#*(+*(#&('($"*)&!%!"')!+#)*'&(''+'+%)&+&*($"'#$)((#+(*%%%%&)&$$"!((()!*##%+%&%
@r3676
AGNNCNTTNNACTTGGCGACNNTGNGGAGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTNNCTCTGCGAGCATAGTGCCTGCGTC
+
&%'"'%*)"$$"'''$%*')("*#$*'!+'++&")+""*"!&'%"&&!#!*)$$)%%&+%$&"'+%*%'$!"!+(*&+$%*%$(+#)!#)%'+)**+)+"+
@r3677
AGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATC
+
H3)%7)%#/;#%60*E:7,H'&#1/8'!)A%D008%1>,++-+9<-$;=.?5G<.,2&)B@5B#@$FG$&)0(-1E&.3)%/DB.H!FD69HF4:(',C39D&8A>86+*0>.E'B.4?B&?7@FG90*'FH>1.%/7F'CAFC1''8?8FC)GB%!#214=%=%8%-+1(*C(!6?2E+=&3/-)CF8E
@r3678
AACAANCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGA
+
->@/#*:C1,8B%E=F9EA7A#(-'8(%F/!56;48B7CF
@r3679
NTNTCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGNAGATAAATGTTAGAAATAATTT
+
&'$%%+'(#"&#$!(#($#!%*)%+&$'%'*+%%'$$""%)((!%(%+&""'+++!&#"()!"%#'!##!$$#%(+(
@r3680
ATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGA
+
F")EE2&?:;2(=#"$"EGH&D'F00?>5E+5B";,.@E&?93(29EH:!EB9EF.86$>A%=,),
@r3681
GTTTCTCAGGNNATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTT
+
,$;:(<?7!&>&0).'%?FG*(6=+5?>@)>3$@<B86C%@D)HDB8+
@r3682
NGTAATGTTACGAAGATGGATGCCTTNGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCG
+
2>$#3H9<0)''H#,CF3*.),FHB+)/0*9/EH:##F8<A-CFG&,0,:BB#?=G59;%9>60<?D!?=7G)FD&C.8!%/&':2+BC0$GDCHHH?8@!BG60D#)+-
@r3683
GANNANNNNGNGGCANGNAGAATCGNGTNNGNGAGNANNNGGNGAANCCCCNCAGNNGNTAAGNNANTNCANNCANTANGGANNGTNTNATGCNCT
+
#"!$#!!""#""#!$!"##$#$"!#"""""$!!"#"!$"!#"#$#$#"!$"#!"!""!$"$##$"#$"!"#"$"""$!$"$$"#"$!"!!$##!##
@r3684
AAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGNGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTNGCCNTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCNGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCAC
+
B2)C,650!:'0H44-!=/-?<."7<C4:+%E%9:(9BBF1":<0<@!4GA>=.;G?>'B:31*?7#&;ED#;9<'H1&C9&G'D$B?H37C6,3(E3D8/;&.::.8%)&5'F;<8H%,&,G;$-;!1":F87;0.B49#('?<E'//!@G250,-51?':%,F60!H61)E"$4F<,DD:$H*'7&%1,/C25!#&,G0=;7E!E,E$F9>.<&*$-860."/H7'?9??0CB@>)B/E6:@"@&+%$AG-;#;8":G8&D$8A;,.B-H)"7%"@",?(7#!36:&/=**HD*-.H8AF.3<4874,F<<H4G<C(>%(5!,E2):=GH:"D,*<65D=%@'(7)&E@+"53GD-)C9D,C'$6+!?BH?;
@r3685
TTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCA
+
>$F-)9?4$;93@H'"'C<D0<8/$D08&+%,,5D=8:@9@9'@&<H9?
@r3686
GGGACGCTGAATGATTTTCTCTGTGCCATGAAGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCA
+
/53;6?1>8BDD@+02)$H!%1:>@$AHAG?/>="-G>,A%1"+F4><":-AGH:;DB@+8?*-8<8?"B"&@,6+!>=+B566D37G&<%)9/<'F<-6@&6H1,(;;7.=CHGE0G-+%.>6G=.B7$018(-DD:/?1%-$(,G#@D*+831!%C/>A#@7-@1$@%-H6#!457'2;9006#6GG$G1&,G*5;@7B0/:#:G(2B?718'AEAH8962.<!!?'+6G)@?96::G)D:-E8
@r3687
CTGATGAGCGATCCGAATAGCTCGATNCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGANGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGTGGAGCAGAAACAGNAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGAC
+
<!>="&14@"DF+>3H"#(*@D7,>$C!/>47A@%%81>,?"=!'H/392=D47=;F574H<::EEA8-12&FG?"?"!5740&?-%9"4#@,7-%HH<41*!4H5(5/-CHC*"282D0B8B*F&)#<72H$5%3--HA7;?'A8=C0B@D27D;7(A4>%.5@,"A1B!=A@6*>@-@7-9%6#D$F4/=/,8HF=GC5E;*8D9$!:+G?#%CA&A=D(14C+C>%2#)A+)&$C/B<D8/D;<05D<H+FH&8+93;?+46:66:6584-G.@?$5E"C':81$@*4?H,@C?C9.==/F"A.<>F-6F?45E-D6C<4>"><4*53
@r3688
GCGTTTCGTGTCTCTGCCGGTGTGGCACCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGC
+
@H3H!.*1FHE$)?H@2**"$A;A&DF!4D001#,>*"-"3!/5;!+B2-%A::AD%)8)#'D%8(?B;8=*2=<E#9D8#;
@r3689
TGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCATCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGAATATTNA
+
"<E2)97"!)&+*:>B&0)ED#.(BC@?BE/?5G741"*1!(=FB"8B<:D+H'"1&72HC@,A'2*?)*+DF!(;:?$&$1/;8(9-H)B:D<>!A/)0H0!+06/($99B:+*2GA+&>87#/2;5?-9"/19>/C3>?/#2/'HF:0/>)$C'C,4=<%"&G4=5+BG<.C'16E/DG61<8<C($%:&A8F%.3?+:G1%A:A$E8>9+F"'!&B
@r3690
CATCAACGGTGTGTTCAGCCAGTTACTGGNAACTTTCCCGGCGAGCCTGGCTAACCGNGACCAGAACGAAGTGAAGGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTCACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTNGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATACGGNATTACGCCGGCNGCAGNTGAGCTTGTCCATAT
+
@F?1";&5.G'91-DE-$2=8,+>7'9D!C==5(H3,>..H*<&6&*1>="C.BGC4E?*8H9.1%/).(C.?6B&A+)(6*<:"36%C='<-+;/B!30:3B(%6&?,A@#/CF97($!)/@1"C#'E9'B*D..9';6,H?5-!-(<@-@/&@F%"E3?%.'70A8A213#$81$"7>'#@4+?EE/$HEA!!D=15$%(%*%$F>=;4;4GH5)!;2H"";GDBD#$')5@=1A*!HDB9=-4-;'#29"H'%4F+71;8(8%6=E0-;C8:48E?:1685GE+B@:*E/H03"+"-&+2-&%;$%<5#.9)#7H)2'$&=,,@==3'*@0(A1BHG*.,#72GD(C%<'.634*.<!D0B7#?(2EEG948&#C@>.G4@#9,(%"H?E:,)GF.5+8&2'88AD/'>(A+7F4'5"EF*/8E<-<33,C
@r3691
ACCATGTACCGGATGTGTTCTGNCATGCGCTCCTGAAACTCAACATCG
+
5<,,G5?889%D3)(1DGE4F:A$E20<E5.,<35:HHB90B19/5/5
@r3692
GCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGA
+
;<-->=?"(,'-)0,=1&,CB+#2'$A!*9?+H5!+,&E>=?.2;+
@r3693
AGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCNGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTNGCGGGTNGCGTCCATCCGGGACTGC
+
&+'*+&+&#+'$%"&#'+#)&"$!*(!''&'%%%!')++(%&'')&#+%)*#))'#+"$&#"%*#'#&%+"#+)$$)#!!"'&#!!$&'+$)')"#'!*')!#$'(%"!'#!+&&!))#*'&(%$#$!!&%*
@r3694
CTGTATCCATGAAAACGTATGCACGTCTTTACCTCCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTCTCTCCCCATCNCGCTTTCCACTCCGGAGCCAGTCTCGCTTCGTCTGACC
+
:2E9#8*!25*8F/G88+?E$.:%603H-G$3F.G+D:-)G2;82-=5H0:CE)6#:=/H?>+B<.@'!H6)E+7-/D58@=9""")79>!D6!17=<,68:"4':<F!6,A6<43$96!6HH*+$6'$&;68"%-"'D=B<'*G#EG!=!/>6D-',;:)H$B/C/)C
@r3695
NCNATNGCAGACTGATGCTCTCGGAATATCAATGACGGAAACACTTGATAAATGCAAAGAGATTCTNGGCGGAGAAACCATAATTGCATC
+
'%$'&"&$#")"+$&+)&)##((%+##*&$))%)(!$#%!"#+((()&"()$'#&$"'))($!#'"()*&'$("'&*"'&)++'*&'%!)
@r3696
NANNNNGATCTGCCACATTACGGTCCTGTCCGGCAAAGTTATCTCTTCCGAAGTTGAGTATTTNTGCTGTATTTGTCATANTGACNCCTGTTGANAGATCCAGTAATGACCTCAGAACTCCATCTG
+
#&%)"+%('"&'#$!%$%&!$%*)*%#+*!(!'#'!!(*!)"(*!$'"'""$++%$&&(*+)#!'*$+%!)!#$'&)++"!*!$$%"'#'()")!(*!)%%*&(+'"#$"!%""*(!!()'(##$*
@r3697
TATGACGAAGAAGAACGGAAACGCNTTAAACCGGAAAATTTTCATAAATAGCGA
+
A6*2+6@FAF9AC'7:*;C#8;!G;,4(?6=:F0$)0#BG,??96.B($-)6A#
@r3698
TATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAA
+
()()%+"'(*"%$%#'&"+!$*+"+!***&)!#"(#*&""**(#'
@r3699
CNATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCC
+
'(>($,D0E'%*62'6=-#E6,?%2")-<3;/.E3"("((>&C!.!.-
@r3700
TTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGG
+
=->,;*BB$-:":A$=!(-/??%8&5+93C;:&D/!GD2=91!8/@!!@;3$3HD*&=H60(AB<(*@:'F>E#&-.25G?<7+(=5'94
@r3701
CANTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTGTACTCGGT
+
%$+%'($&$"&*%*$%+%$('"*$'&&#"++#%%)"&)$$+%*$*"*+"$(&"$!'!%)!&*$#"'($"*(*%$"+&$(+#+&%!()($"'(#**+
@r3702
CGAAGGTGTCGGCATATACCGGCCTNTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGNCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCCATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGC
+
%:'E+D/7/"ED%E&8$0*;+19/8)A!$08,:;6$=!DF:5)@/:3E%<6?1,8C%9.;?3#.54#$+3/>)A(8("0=@"!+*/#H!4E:+@89.CA"$A%'2GD%C&=G6D9!9AH@:5!5;B>.8"B4B16$82C&>GD5C."').1&AH7E(0-'?4B#'1%-9%(E5/@D<$A329@E1586=D+*.GC!<*-/;2C+78!:E,:==2)<E('??+B6=:4&
@r3703
CCACATACNTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCNCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCNAGAGCAAAGACGAAAACATGC
+
;?0F+58<.;'$$HF.F%9G"23&'D>%:2F!,B5#9!-=>&(9$A5E'690D19*!,326H4)<#/A816&*E>6#44"7GA3,%,4>E'4/!;3&HB)*DHC,.8&>*(;C6"%)B$4E)3/ABDAC+"85.(C:70?!*4,*<00CC+>,,27'&>!4(8"#33%.1C707";1+A1/?2A%:#?-@2:BG6#$!D:4=??
@r3704
ATAAACTTCATGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCG
+
7&C%G-B=;%D2>H-8>;1,3'A>(HB1&+B'@B2@0:!.<?G=F1EAF<BH8EHA4$%'0!+#5H:>&&&D$+H69AG8'3B#D("
@r3705
GCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAATTGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAA
+
&+!))&'+#"%!*)('%)%))%'#%$#*"$&)(*&'")$)$$"%*))&+&)%*'"&!#%)$#)**(($!*!##+"#'*++'!$+$**'*#+!!$(&'#%$#(''*$%#**'"!$&*!#"+
@r3706
CACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCCGATGATCAACTGGCTTTCCAAACTCGNNTTCGTCAAAG
+
3,-5:!F>*GCEC6%F,5(0A@@1',((.!EG<3+HC;:1-4/+.F#68)/79EB#6(6,7=*:02A5(.$?%5%<@:D#((+3%H8@((<
@r3707
GTTCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGNGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTG
+
4E;F@1;4#9,$AD7#,7%3F9D#F?'.C93+@1C;2:A79C=#F2*"(*)+G.3&%H!=6AF7'A@0H:!0B)%$-%7@.<.*>'3.64,<3=E6+>@":73,F4:/?6@!=86A?1,=E'"!6.(CB,/.C6"4!-#GG#6%F+*#C",H",*?G97'4<64;0;4E/2C&=
@r3708
CAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGC
+
05">%&*/#$448'%!F6>$G4+)4-F:4'+D966B)B&4"AH>/(6')F9;!)+C,H&'D8<7<E%:C@;>/.)1&.74A-"$5=*B%&65%8C3"=!8554/@,E2G&45:D;(*E5$>9&*#AE-;:E61@D;*?%)/0E4G#&7:4C-/
@r3709
CNCNNNCATGNNANNGNNTAGCANANNCNNAGNNNGTNCGTANNGACAGNNCATTAANGATNCNNTNCCCNTNTC
+
#"#!!#$#$"#!$!!$"!###$"!$#"$!"!!"#"$$""$"##"!#$$$!!"$$#$#$$$$$#!##"!"#$#!$$
@r3710
AGGCAAGGGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCANACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGATTCTTATCCNTGGAAATCAAACGCGCACTN
+
*'%(#!$"%+'"$'#)**"+)+')""&(")!+%*"!#+!'*%)&)#')!##"+&#&'(+#!&('$%()+))!"(&$!!*"(&!!%+"&"!#+%++%+)&+#'&)'*'$(""&))"'#$*!#)''$+%+!$(!$'!'+'%&*%(*'%%&%%#')+%"$&&()*)+++(()'!***$#))+")&'"#+(!**%$+$$(%)"!$
@r3711
NGNTGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATT
+
!'#(*#%##&+#&%'++(*)*)!)!"#****%(#*"#)**#(&$
@r3712
NGTNGCNACTTCTTTCCTTATAACTTTTACCAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCGCTGCCTCCAAACGATACCTGTTAGCAA
+
'%'##!#""!'"*+(('#**+*+#'%$#(&)""%+"$""))!"+%$!&%!)&&!&%'!)*'"+)%'!!#""("+*#*#)(!*'!!%*&#$*!#++&%&
@r3713
TCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGC
+
=!2$=B<5?:E3"0%:*)%F&1F61,1(/C8+4*@$02*#2!@&'#(D
@r3714
CTATTTCTGATGCTGAANCAATGATGTCTGCCATCTTTCATTAATCCCTGA
+
@;-&*8&!FA/6-3B=#7?2$#08E@@EAG%',B/:18<:/B&DE>.">BC
@r3715
CCTTCATATTTAACTNAATCATCTATTATTAAATCAGNAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATA
+
B.6/".GEC2/="#C$4FG+9-446@H<HG#/D.%6'!C%%%24:;2DG<>>F=/2*D!+&#2,70-%%7;D)/66=39:B$'=8;A@%A9C2?(<
@r3716
CGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCANTCACCTTGTTTTCCTCGCACGACGTCTTAGCCAC
+
B)5?#G+C@5'9%@!@3@-A!:>;EA?.238265)@)6>F/<=1F0G51%"FD!@''<4!$F6G326G/1
@r3717
TTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCC
+
/($GB5(=92!-&$H3F(/%CA>8#EE.)E"@B,7&7%+?"%:/?2D;#+$"7$C5/<&9GB=
@r3718
CNATNATTNNATNTTGCNNTGCAAGAAAANGACATTGAGTTTAT
+
#!!&$)"("!"#(&#)*("&"+"%'+"%)%)&('))+$'$+#'+
@r3719
CGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCGAGTGAGGAGAAATAGGTGTTCTGCTTACCNTTATCCGTTGTCTGTAGACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGNCCCC
+
??65=C,)3<F)#'#)>C-(46)+!"B!,5D(EH?2'1@==4*A>8D;G,)B8)!D@$(F>@=?/=26*G+;:%:>/@>36B/;$%36G&F%E164G9.1CD2$E;##%F)()F7/H2;('@!13&'-BF8.B:2A406@AC2>%!3#A/,#)8*;7C@+@5@19$4'EAEF"/:;0+9C=/3"75*+*--3@3E9H)C'
@r3720
TTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTC
+
89A'/)C"9A;0?/H.4>298.>(>'?@26<2C=)((-$7&+:E,
@r3721
CCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAACGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAA
+
@"<DFCA@E;:H%,3>8#!@G8+1/:BC)$8='-#B!2D,,A6+/!3=*D4,F3<F1);))2+-#0G97E,1</48"<$+"EF*-";6,:EC7.F6@3F#/+G.">+1H>68;)=!G-/67/H3,0F%5:-AA",;27,H%#3H?9"!'3->:8&FF5.E@=21*"%B=(0;0)7,%7A*/5!9D8'6
@r3722
NCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAANTTACCCAATTTTATTCANTAAGTCAATATCATGCCGTNAATATGTTGCCATCCGTGGCAATCANGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGC
+
!969#">!'(%-?E@+5#24+C,=<AD+8'E-695A*-32HGG3-:;F;>G+@E<70#7%AG;:5C?%'C1:6)2.8"?F@7'4!!>G&&!=-(8%52,G99@E&+40%1&85%)&,2/C*<C2!F4?8*B6))2?:3GCD&E&?!HFC>7!.:38&")6?C?D?D&##&7-&/2?+5)%;#'@'$G"'0"7B%=,E7)A=6/<4F8%A/<AA.$#@3+HBF:4#$,"-F**40G?!?A-6(;"F4%/125$B)<$-)982'1'7+&$88*='%;+$5)H@)G/88##)5$=92:B-A%(+A2<E"+05@/1!3$F4EF/5H>2DH3,8=39;%10A")7*GG=):H-:#'-?*CDF
@r3723
AAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTNTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCT
+
>:"2<70!42<?6&0$.5>1'64(9?(0%$>*4;*(%&#%)"D-D4203&BF8-*/HA04HG-@+(BG0G>#5;)&'$4?9-<(>(**>.-;!.165$G+*2A3=#.++-B?H/HC+F'9G-F#80A@3H*&A*&9.B+'G=>7'!C$4@2+/+'%C788G:H&,1F"5204-3-3+>1'$<5@EF<<;9$F*;%>:'8/*DG)F#1083>13&H+HH;AD/9-(!>)A2.6/FH6&18$9/?:..-/,$<4@(C'68C#E/>*6$?/D0G3(F0*$(H#B-E&4A*<+99C>/)96?6/<?';<).(-57B!!5-3)@C&%2;3G*3H3A7&0),C/9A"G)4<?(=/@D54+'?9<<7',&D5%2,=)/!,/C3,!B521A8%@='*,<,,''A&93$2)35+:$=H761BGD>-)>-,
@r3724
GCTGGCAGCCTGTCGCAGNCGGGCGATAATGCCGTTGTAACCGGTCATCCCNGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACNTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGANAATGCCAGCGTCGCGAGTGCC
+
)7+H<66C.4E72!B7;G;5F!>5<@<*%E8!!%;#D="""(69>761E7+7/=F=-</%C2<@/:D-)AH.52"%>4AG"598D163@D9*-#-4*&0&-66F!*9%%H$$BBE>5$D<$$/0;;71%18A>;2D?/+B(&"9>*#'=9%A(+FG"7%CEFH)B*B+#6.-0(*'#)7'F%7%2)*/=G
@r3725
TGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGA
+
,:;.,H84F-@@96*%9.D,)"24%!2H=;.1477.9&>27CD@F&G-,:.!"/EG"6F5GG-"G
@r3726
TTACTCCATAACAGGNACAGCAGGCCAATCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAG
+
-E/-BFG042@2E?@,=$"38=F8.$+"!?13-98)2."G@?,D47G.7:=4&F?'@40?BG>*;B.-2C+E;-ADH7%!FF#E2/#A$??4%%:<=6A*3?1
@r3727
AGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATT
+
'/-C6";9+B!;)#?2@C(:<()-48E#"AC'3@8>#07?$8+7HF=$<<5H6B1-%>DC+2>>>G$.-.EDB34A&:F+85DB:A*&!5+A&D%$+8'==!1;H94/78>/5@E,5%&A"(%(E;?&&80/),?B
@r3728
CTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGNTAAAAAATATGTTATCTGCCACGCCGATTAT
+
7&C'<-2&G)@.#7-">035DDE1@=:>:&<,B6*390;&GF(3E;(-%=4B-A0.E0<('&8%9!$:8&+<!FB4"D0HBA:C:"1#B%H-
@r3729
GAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAA
+
7"8?DE#4$:9;;"C&$&FC)1"?48G"G(<1C5*8*=&B7@?;76'E?+)/3E>>?635>#609#31%ED0B"/7#0">@/!9A;H6=?/8(=!3'F'4;&3)54;
@r3730
CCCCTCCAGCGTGTTTTATCTCTGCGAGCATGGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTG
+
,".1"D%=;>C/,'')B";%%G*%1*5+##<1"H36GA-B/944!6)>)*GC)5/0)D,)/68(C;3,)BA21B88="'<>17*.5#
@r3731
ACGAAGGTTGGAGTTTACGACCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGG
+
+*'(!+*%)#'&%'%!+!%("+'$##(#'()'(()''+"%%*)!#)%*%(+#)(#*')+$#+
@r3732
CATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGC
+
4&'(B:8(6,+G#*!H9?0$4()5B6:"885G3$63"D6&5*79G0FHC1C/6?41H7;6&9@%-=-)8F2D->#$F6=9A(H:A6E(%2'<=C6&3&&1%9/>"HDG1F68;?<4-($:+"#F9*
@r3733
GTCGTTGAACAGTNGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACC
+
*1@CF$=B89'((&.56++9(@A./1C>($A%8?H=E->&5-0#?D>/AD@;,CC(H7D5#C$'#H,&4::B=1BF;:57A5==4D>/CEFB%C#&>'A!<:'70
@r3734
TACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCA
+
B@@,45B<F0H-9D@2?+%!@0=H.3G*.B<4B8;*:F'H*+
@r3735
NGGCTTGGTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAG
+
$&8)A,>@'8#5E388A4F'7.E9@5A&G)E@8B/E5,B:%3=A1@:.;,1#:#%G:&>!
@r3736
AANCNCAGTCCATGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATNAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCGACTTTTCATTTAANAGAAAAAGTGCTCCCGNATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATNTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGGAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGNGCATTTGATCNTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGNTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAA
+
&&!(#++!!)&%!%('%!*("$$(++)!)'$$$#&(#(!&#()!"$'""+((""#')"%#+'""'%*%#)#*#&$'!$)*+!+%#'"%&(!*!("%#$(#))#*(*$&&*))$'&+**+'%%$%!)*$$(($##'&#+#((#'"$+%%(!!#$%##'&!)!!*"!&)&"%)$&)!()&&)%!!)*)#+#(")#$$'$&"""'')++'!"(#(+"!!*!#*$#)+$%'+#%"'))'(&#'!++"!%!"*)&&"+$%*+"*+#(#*("(!"#$'%**&%+#$#+$(!'$$$%$"'!(#&!"(**$%)&%*!&!)"''"#'#)$''+!#&($+%%'*'&')&&**'##!%+&)+)$(#*#%""(()'(+&""')'!&+')*!$#$'#%$&(*(&%)!#)()&#!+')(&#*"$#+*+'*(&!'*!)!#'+"('##')!*%'##+(*()"+'!))*")!**!*(*!+&*'*!$!%!(!&*++(('#''*"'$!(()("'*""'$!$'&(!""#!$%+()%+$"("!)$+!!'#"#&+)*)%!#*!!)$$$)!"&!)&$(&*##%$)$#!+!
@r3737
NAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGT
+
!&F>(?-5(+=F4*9D=7.?;G<@*3(?H";!.3.-!2%,?!&<:H#F$!EH<7;()152<.87,"0<&9?9<6=>384.)
@r3738
CACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTG
+
.7?<71B4BE)-+<=69>(..%3/(<!F4C0!8C-79CFF+"&>$1%
@r3739
GAAGCCATAGGCATTTGTNATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATT
+
9;0?(38>A(F9E+BF:!!62=.EG@7#5:FCH7!%FG744%CA97<4AH$9;8>F>CA$2FGA5E6F8='&-#D,1H?!7FF$<?((.DGB@9/:.E=
@r3740
GGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATAGAGAAAGATTTGAAGTAATATTTTAACTGNTAGATGAAGA
+
F0/#04<%&A7<F*'E;E&:1/-D#'4:5(;F@HB+?F*#-E6</'#3F(G!19"F9*-@'C?@)&)#/33<&4>#*#9H>;H86D!**9?3691)@B%D+&H
@r3741
TTANTGCCACTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCNGAACTGACACAGGCCGTAGCAGTCAAAAGCTCTTNGATTCCTGAAACAGAAAGCCGCAGAGCAGAAG
+
$'&!:&3$'F%=%;29""50(0H:0HFA/39134D1H)-><A+680,>%G,(A)%1=2C37/!0!"%:=H.FB.G)E4D&20",E-81&E%%<H3.3280*71EG!D+!0;(&"?=13
@r3742
TTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTG
+
/.(0"&EG,$?%14)8::23=5,H8<H>/G4BH724507G-2B$58'<:2,7B"H"G24"7"!75"6
@r3743
GGACGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCC
+
(+&@3>9/DB2HCE@3&@F''2H!<9/!9&"(50+D%!+%2@("B9>.1<'
@r3744
ANGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACGCC
+
&*)*)+'%*$!'")#"%*#)$)$+"&(&#&&!!$!'!('!'$$&$%&
@r3745
CGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGCCGCCGGATCGCCCTGCTGCC
+
.$=9845-EB+>*?;:5-2"GC=E*7E88##<A/;H%8E5$%A=>H54)>/F:.B1;.A>!G)%4*8$=(0@20C5,$!;D:$66B$//G""7D'=-97B
@r3746
GTCNGNNANCANGNNNGATACANGNGGCACANGNCNGAGCGGTTGTAAGTTCCGCAATAACGTC
+
)&&"$&$&')*#'$&"*%%"#"!#!#'&*$*'(!*+!"*)++!$(%+!)**&!++&+!$%$*!+
@r3747
AGTATCAGCCGTATCCCATTCANGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCC
+
".H>C-+B,;E($AGH%;,?0/&;!)7'"84?+29C*0-D=!3@8/G4*D1.F:/%'-C$;EH'@'F0D%)1@1#%4C)6H&DGGG616<0#-&A49!E3#@H"24-G3(3&D2<6F.0$@G:G#,AC(EG)!&@)+$7/H%B24-=!)E8:H(6#-%58249"1(:,
@r3748
AGNCNGTCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTNCATCAGGATCATATCGTCGGGTCTTTTTTCCGGTTCAGTCATCGCCCAAGCTGGCGCTATCNGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCG
+
"%!%&!&&&+&)!&#"'&%+#&!$&#&'#$$"*&!%%*'%!++)%&*&+!&%&$#*&'$#)$*")"#$*")))+")%#+#&'!)%)'$!+)"!(")*+$*(&$'#*++"*)('')&'%'!**(##*!#$&+*"$"#+)%'!!!&&++!'$&&)!+%()&*&!)%$#$')*!)++$#"#$
@r3749
CGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCC
+
*FA8;::1*5C.#$@44<*(*B<!F(8?.B*+DA?H)(('%.&,B>)!38A2(%71:GF.F(D47DG'5*.;3.8
@r3750
NCCCTATTTCCGAGCTGGAGACCGCNGTGAAAGACCTGGGCAAAGCGGTGTCCTATANGGGGATGTANGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACATCACGATGGTGCTGGGGAACACNCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGNTACCCGAAAAACTGGGTGACCACCGGCNATCCGGCGCGTGAGTT
+
"*"*+$$!!#&%&"%*+()&$+"""(()(&'#%'#'&"%$++"#))"")"%$+%*!")!"#(#!('!''!)#'&+##(*%$"$)!)!!%*%*'$#!!**#"#%$+*!'##+"(!&((%%&+&%'%!!$&'+*&%+)*()""!&+*&&)'+$%(%&)#$&*'!###(!+"'!"+*(&$&!"(&%"*'**+"#%%+))$)$)'$"""+%)(&"*)!'&+'%"#+$%#"$"&&%'%*+%%#&&*%#&%(&!'('*%!'""("%#%&&'!#''))#''#$!!(+&%+"*!!&
@r3751
GATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTT
+
&-'(5+&*A2">,,%&F71"/!9,F607<)20;(C8@F.H0'4A5(F?H!#203';2G!-)>6",*0CF5
@r3752
GGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTC
+
8:!0BG2%1*8#$,1@#,24?C$(@@GAG-("3)*;6@,?1"A+E)H=6:,)0?/H+96&E,H0<GB+<.B93-:.@+/C-'B=40+=9.4'C(:7/@?-@075A)#A.$4*HE"7=,%&$!0745B*;./D*3)C*0"&?226?($5A*D:;:FFD/3#5=3)1AB)>6+H
@r3753
GACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTG
+
#+*+##$!$&+%(!!(*!"(#!#*&$))(")$(''#%*))#+$
@r3754
NCTTNNCCNNAANNNNNTANTTNCNNCGNNNNCNAANTGCCNNTNNNTTNCGNTCNANNTTCGNNTANTNCNTANNNNTTTNTNNNTGNANNGNNCNCNTNCCACANNCTCNCNNGNGNNNNCTCTGANAGNNNAANNGC
+
"!"!$#$#!"$"!$#""!$""#""$!$#!#$##""!$$##"#!"!""$$$$$##"!$!#""$"##!"!$#$##"###$"#"""!!$#$##!#""!##$!$!#$##!$"$$##!!!!#!"!#$$$""#"$"$$!$##!!##
@r3755
TTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCNGACGNACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCG
+
*H:-H,61D1H>=:26=;9E$<H,;H@B)3<!"D?!61<5.5-1@H>)1>=1#'$&"8?#E31E<72:B;A%=,E""(>'*"$=5E"5)CDH"&28"E?115,.;7!5082&3=@#=2=F:3$CB5;62@!HEC:)A?/6&8"4CA20!B('!)")&*2!*3":@+"C.4$D&%&0-C&4A@89#-/C??>6<$@05025$.)24-C4#?$6
@r3756
CNTACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCTTTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGNTG
+
"!+?,G2$G'/1?32%!#/B@#,7!"A5@F)72+GA#>=@0$/C>HH<"63#2(3/().=96!3@A!#BE!".&&$/4-87%BB934
@r3757
TNCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGNACCCCACTCGAGGTACAACCGTAACAAGCNACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCNCCGCACAGATGGTTNACTTTGACCGTGAGCAGATGCGTCGGATNGCCAACAACATGCCGGAACAGTA
+
*#,.BB'@G-(>3.!%<)B&#+.*4>.H*#<2A!#738B,4D)<#9>8*54'$E4?*3>2/H9@=?HB'?E-%9$A)>7(0(H4BG2B"??$E1H'1<*5-',2:@)GCE/?A0<%9#A-,9(FD+5':!!3A?"C>C2%H-?H/6&;+H=-/(#B/0,!F"H!'#8+9/G.D50%6%@98DC=-4C)6#?H<:$B?.5-/5'94#$@7.(=&A8!;'3'>G!;
@r3758
ATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCGCCGCCT
+
<10,9,+4$5B%.1H!9%,F"67$#!-*1!1@8*@!/>!41<9"94>9*2+H1-%<,2B40@+"5<#3A;9#<!C3)64
@r3759
GTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATATG
+
4#:3"=?="4:,##B47,?4$&E=1"3:G62*!+DBB.<#+(5%?9(HA9$/,>&4/1H!>:9A:,+3G>D.3&-)."$A@D0%56F)0F+#$*B+32<=F#0#*"H#2$"77B893<A46#/@>1*<@D1@$*1%;9;(E4
@r3760
NGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCNGCACTGATGAACCAAAACAGCACAGCAGCTCATCGCCCGGCTGTGCCGCTG
+
&@+%%4*&,B+'>.8*+%#$,!A!87?C'>A56F3@$-CD@C.<AH+0=%(!.7A!A)99E93H)!01FB%)??+@<0>%,(@-6#G*<A0C@&.G1D3">24D,"<.!B*:
@r3761
CACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTGGTGCTCACAGTNTGAGCGGTTCAACAGGGGCCGCGGGTGNTCATGCCCACACAAGTGGTTTAAG
+
+)19=5>9*+73C9%>/32E@"/B2'G./1@19F#<%:=<@H%&,&,11<4#A0BF028!9+"4$639.&+2#,"B8<&&3:FG#/!D(/;DA9*8:0HB9707;*@<FE??=>5G6A%.57!%H290(=*'<0;"2+3A;;@@
@r3762
TGATNCNNCTCTANTTCNGCATCCCTTTCGGCATACCATTTTATGACGGCGGNAGAGTCATAAAG
+
'"!*""*#)((")#)''!&'')$+"$!)*'"#*#)#"#++('*")#+#'#)&)"$*!()*)!+&#
@r3763
ATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGG
+
H??$$!C;F'40;@<E30"6"A-D'?>)1@D97)6@E"#!?(7$(#CG1+&&=#'E>&396-(FC:.H3B"+F,CD$B?1?/E?E0C,)0:=F,A
@r3764
NCTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTC
+
!!2G6A0E()+8F?B&'/=1(CG28B:&CB7;*C=AE$$>
@r3765
GGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCNACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTCGGTGTTCTTTCACACCGGAGACACCTTCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGT
+
@:-B&0#FGD031&@34+>07"4-;9AF4.&E,C95+*3)$6#@#H%"-%;2$%GE/:,?F=/3>D#36:9'+*((%+.6!/6!2:%76=@-/5B9<8$#"G"!84H,6<F>H:#>6!:016E-4@E+;--;-0<E.=B".?(GB8?#0&5/A?-
@r3766
ATCAACAAAACGCTGTTCCTTTCCGGCAATNAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCNGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTNCTCCTCTGCATCCGGCGTGGAGGTGNACAAGGTCGCTGAAGNCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGNCGGAGCAGATTGCGTATGTTGCTNAGTTGCAGCGTTCCGGCGATGAAACCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCTGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCG
+
!@C"F56&G%/D8';D.1DE77&@+#C8HA0=;'#'>6E%&EG=:"-5127A0+B95@1D$F;-1$E'7E-+F=5%;-1'17/5+C387/!A1!2D<)G&A6-+#DB:+D%A,>#&9D&!0@C0."9,""EC#-$G1C?<E-"@/(&;(0F+>+$#B0/<4&E6%12>*#8)DGG0:5+?EE1-2,&/:=@#/3A@0-)E*!D4#"#,B/@807/C$!<7/H59)(2/%=)*1&.G-9<+D5<D:'54=3GG<D!"36"HH/,&%=GGB99F#9D/&3<H?2:-6,@B@*BE:<(*>30B$AD@81@#-;B-$FG:'&$&+D5>6(+=5.3C0?$"A5,!5;/10.:(0.=?6HG>7A'>*!G,3B'"E:H+F@232-?%8%,#7CD<&&4BA.;78CE0-4?;3->0H%@HC*74(,DF*/H1?=.54.:6-(@./-!9-G+H&G));!"+7'+"=0.4GE?)=H=E?4!G09=&);?<AE)==2;#@
@r3767
NTNNTGACANCNCAANTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCT
+
"'!!'()%"#"$((*'))(+)&%+((!+*))&!**)(%%)(""('")&&*!()!
@r3768
GCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAA
+
+E>0<)A,>+A%7E+)B)E*&5C%F+)3A.@'FG#G//A/G1-7H!B47$0%;:*(D#$C'2,$+787"8<(B+6B
@r3769
AGCATGGCCTTTAATGAGCCGCTGATGCTNGAACCCGCCTATGCGCGG
+
+>,F3+;5#9F,%:6&FA>;85C!@*)@D&6=E0(2C-29H500EF?-
@r3770
CGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTNGATAATCTGGAGGCGACGGGGCTGTATCAGNTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGNGGCGACGGCGAGCTGCTGCA
+
+'*6"87?!;!%+/=B%(##F/&:2?,&:=+G1E593A7-@9?02/'2-2!G!95G,D-.?"&%H$#G3)&4E;F'E..3=@);&4<#(EF9/F,CA.3"7(C/<3+@;%'D9;%68>B0,?().>5-A-+,7:'8-27+;0$.,+3D.))C++,/8-"@4E.A44!?4)H/7/%/
@r3771
AAGGATATTCAGACGCGAATGCCTGTTNTGAAGCCATTTATCGATANGGTAAAGAAATA
+
=.2E#>98&>&#(?B%)A!0.-G90,F380$:+:<#2C!.F2);)/C8)F&D':<-?19
@r3772
CTGAATCAAATATTCCTGATGTATCGATAGCGGTAANTCTTATTCCTTCGCTACCATCCA
+
#+'!$"%+)!+*(*%((%'!%&#&*'#'("((('(+*%)'))#%''+)!*+"$"&((($*
@r3773
TCGTATCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGGCATC
+
$*'(**+!!(*''#)$+&&%&&%*##%+'')*#%&!#%$!+%!)+'*"%+(%!!"#'+!*!)%%$+*#$&')+"")$('#&%'+'##'##%#('+&'!!$($()!!*
@r3774
ACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCNCTTCGACCTGAGCAATGGCCNGCTCTTCGTCACGCATGTTCTGCATGATGATGCG
+
=7;73-")H1C5=H,$GC6'9!B&&%DE;<-$6;.DB%C?$$(/*B/2(4E<?D'(145=!7B=D.!C+F.<-**F/D-.5CAB95A:A?G&")=##.29<8+78<+1E@>/5G53;:&)-@E.:4''4%:H<=F&G-9HG"'7
@r3775
NCCGGACGCTACCAGCTTNTTTCCCGTTGGNGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTNCNAAAAGTCAGGACG
+
(+$&')*%+%*"!%!#()%#%%%(*++(((+(!$')+!&!+"(('$#&%!+($'+#%(#&(%#&&$"$+&+)#%'"++#$)%!"(')"
@r3776
AAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCC
+
,=4/615(=B156&?+H71&$+4,<)!47C.D;0D!3"42D"<ED.!2H%3D&3C*1:(+E?F@"1?.$F.2GC$G@D3!6#G5?8B/#@;A1
@r3777
GATGTGGCTTCGGTCCCTTCTGTAACAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGC
+
?,;&/96<3:676'9";'=+H!2=A8>#9#':3"CA/6?5?/C$G!,FF"0G.8%5%.2A34
@r3778
CCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCGGTTTGAATCGCTATGCATC
+
.G'-DD4(,")E.%*)D.7CGAC86:@A*%#&D:3?C!4!C@6"<*.D,123<%=?E>2;A>;;A7?>5.="0>7A13G49;3EF<D-60#
@r3779
TCCTCGNACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCA
+
$+#%%$+"*!)**)'('!'&#$$)$#%"##'#+!"!'+*+)&+
@r3780
TTAAACAGATTGAGCAGGAAGTGGTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAANGCCCCGGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACANCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTNAA
+
?&3"/E!CGE;)*:;/$06'81;E7'G/0A)@%/&00,,?"*:.?@=@F("7D6/26B44&+<;FA4H0+46/?($E%>&E'8;(B;&0D#/<'"@*!@H=9652(H=47FBCG?%<))!B6EE#9;&-@5(,+$''+9/?G+,)',"H=!!A<(,>GA:+.;635@4><8E10<B8)!#A*AGB2@A=@5<**"$35($<D,6,%&605'#;E>14!A!A:2$E7H9@-(:<@?D!&$>>7'#9#-5*G15"?64:7%=G*A*B<)H7+A.,2A4F#82823>(2@497076$@+7+5H8C)D<,%8>C>"5%<C,27FH9.$0)+?C+.*=%1,;!+4<$@$*",.4#&&C#7D"@5@5>076!A3?*0(8'7='$/<B/F%*&)83D=E+C$:>?$6G'5+!C&-.0=G*@A@E+&D!87D'#59<#
@r3781
GGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTG
+
.":8B#!EG0-8=D8."-+#!=GHEBC@>7-C6=/(=C3<7,!?0*BH686(A@>7:55DAB4%DF);'>(838ADD#360D+;5#>1$=&7)9(#D;*9=2#83C(8/
@r3782
NGCATGGATTCTGTCGACCCACAGGAACTGATTACNACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACG
+
#++$+)$+(++$$($+!*#"*#$(*#($'(&+***#)(#"+!%)&&+"%%)$!*&)$+$#+$$'!#&+%##"!$%$#'!%#%%(%#%*)!)&&$("(*)$&"$++*&$$%"!*"*
@r3783
GTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGG
+
;,*?-42/%2;F#13(4>G+B@>1GF3A%D*23C)%<HGC0:?F(')G7=?><"C@,7>-'$2@B0(H+:A?
@r3784
NNGCATCGATCACACTCAGCAACTGCCTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCTTTCCTCCCGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACA
+
*%)C.='"4/3C2>3..4@'>8>3>/E#.E$.5?4/E=0"!H%==#E89.*.&@B(G-)8E+8$=.$<48?!;5CF/<7C;HG#/.;F7.G0"3$0;9H4%5%!:(DBBG7,&,F=5@9&B018A&%3/<7.E21/0;46$
@r3785
NCTANNNTCCTNANANNTTNAGGGNAACAAGNNGCNNANGACNANCNGTTCNGTATAACANCCGGCCNNTATATNCAACNGGTTTTNGNACGGTNTCGGNNANNANTGNTNNTNNGNGGACGANNTGANTNNNCAANNNNTCGGNNNTNANCNNCNCNCTNNTCNCNNNNTATGACNGACCNNGTTNTCCANCCCNNNATGANNTGATNCCCNNNANTNNNGTATCTNNAAAANNGNGATTNNGNNNANNNANCCGNGAAATCCNNANNTAATNNNNAACCNNGCTAC
+
$#$!"##!"$"$####"$#!"#$"#$"!"!"!!!#!$$!""!#""$!!#$"!##$$$$$$"$#$$#$$"$$$""!"!$!$$"#$!!$#!"!$$"#$$"!"#$"##!!""$!"#!"""!##"$#!""$""$$##""!#$#!$#"!#$$#$!""$#"!$!#$$""$!#!!""$#!#"#"$$$""!$""$$#"#$"#$"!!"$#!$!$$$#!""$$"###""!!!!""#$"""#!$"$$!!!!$!"$"#!#$!!""$""$!"$$#$!#"$!!$$!$$!$#$"$!""$$$$$
@r3786
GACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGCCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCANCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTACACAGACAACGGATA
+
,&?4(!9=-.7%$/8*<229<;9C5<H'-@*EF?:-D9F94G73):G)"6(F2,#$.(0CC&G9;#2D9=%33*B!4&*/C486<5(A8;9%;.-ED1E8'*C*@!$=#&7>B.79'3H=D:#0/9FEC'),)F=H&*+%7$4G(!43/?-7AD8&$*#-1-*,85,;"-,'HC"!;!!>88=64-A,<E#63G$23/B57"*-6GF&;-0@-@4"1,/!290D?$28#7@$2&1))4()!9E+4&&B!.G?33GAA%"2-$0B-9
@r3787
AGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCNTCGCCATTGCTCCCCAAATACAAAACCAATTTNAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTC
+
4!G0CE;)/A3(1+!4;4'.6!>=%9=F0;//CC72?37+,548G-F"-H0$%9(F:EB:*%8C)B<";331H?+<?")H;=6E19G12G6E(%(2HH?3BE7:!><A&0-+6?H,G=@5<85.<-7C11F,F7/2BD/AA%GHE#%0:'"A1
@r3788
ACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTG
+
-"F1G=G*&FD"%4(5B%3B87)+<E(*)>D;513F"0D:&'*0))24,C0)'B*2,.%+.?!$2
@r3789
TTGCTCGACATAAAGATATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAAC
+
%5DG86?FG@E-D:-.G4&@E2,G8#/--#*'+(E-)79=8A8-+.;D*<;9"#+/;/=A<+743!B=0=$0):-2E%;H<
@r3790
CTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAA
+
$3?%)!+H-=(7'3E:CD=#$8-><=D"!9/616.$!B(75(1E.8>F$C!AG$?0?$B1%.*;64$1<&@A813'B2A.:B")/6"C:
@r3791
CCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCA
+
B#-9F*;;8D<7B+6&'2,*#"DC$+35B,')$CHC%-#,F'+9
@r3792
CAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGC
+
3=B=;#!92;%*@B,1HCC11"FHA<B*?$+6%46(@B%-2;<9=;+!E/&A"211B5GA+!&8A$(+'%(A6%@4D5G)@@-F"8E@/A9#!&*DFBG;#H55)'B-,!=
@r3793
CACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAAC
+
4#%:?2!95;CE,..<>92H+<H0C-;H1(:6D27:F#,$F/"C"A!A+20<HH#D(
@r3794
GAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCA
+
8>278G?1=(,))-=.6=$G1%+H7-#!?3E'#H;BB7#E12)C
@r3795
CGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTG
+
3:C/-'"C&E$3CH3'=F<6.).#&2"=8A7BADAB1H34688*FBF=H#7(<?;*07>B;-/B*F3?9H)"=$-4#.,C1A$>(A<>,B/2'C$/7=G
@r3796
AACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCAGAA
+
&955>H:+3G*3$-9+/.7#7143%#/).A#0;/AA<H5;.CD*!%HA
@r3797
TCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGNGCAGAA
+
(FD#77)-E#DE!%/--4<+BG<1@-4/$05,81BB2)45@%F7$2A'2H4$
@r3798
TTTCTGGCTGGTNAGACGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTT
+
)+.:;4H<-0,%8(5710.,37-1+-/G29C"(01$8G+=#./?+,')B&F@#/(=D?=>
@r3799
NTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAG
+
)'(+'"*'!!'''"$!!""'%&+!)+"+"#)"($$&*!'*%""*)(&#!"!("&!((*!+())+&%)$
@r3800
NGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACNTCAGCCGTA
+
#B',>27?A?>7.:A4H?10((,+/D(09F"3F6-;-G-G7/()1$E+0>9//)<<AF#"<2DEG:>DC?0&&*9E42C.-;B4(C)GG%7;)''?",::84"&D?:?$/HDHA62$7:H9.-$G85AG'+E1B9F-'
@r3801
GCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAATCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTAT
+
/!2$5>9D$4'8)'H@8;9+?D4(%1&D+26A:H.;&H/3B*/1,:1CA+2><85GD>0.FCEH1")?+%3$$EH%!!(++/470#=%B"6B&9)&'%418C@)?+H/65"E4GBF';9(CH3E!@+C>+)20""9.;9,*785-:%G9%@BG@54F+,#HB=D5#($#!-F2'7(&?$CA;;F-HD3:0
@r3802
AATCGNTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTCAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTC
+
8($;FC&4)0@!"C&@C.;+2C5)(,!-B=A?BD'=F:H1D'D&<!@2=F>%''=/E1*:=&81G4E*:.'9A-4H#&$4:/0:6&<7(C0H+5CH?!*3=>?,@!*<4.#1<*8*#;3@#!+=D7CA(E"%>-#!05D59+*C8*;F+?*>)6<25<A
@r3803
ATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGA
+
A!F7&//@1=#!D:*,!4'2E0GF-$=865(840+9!DE@'3?9#@#%FE$6(8B!2%?8C<H<:'(&2/3;D6+05A6+33!C!*D'(E&G><"H76G>F<$B0G?0;/9D?(5BF<+0C!56G-H=&4A/<#/
@r3804
TGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTC
+
E/A/>*>5-*F/!$3:1$B',=#*C:GG@8@+BAG8HE46:G$*(4A>35%87E6+$HD$>F&2H
@r3805
GAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATA
+
4460;'@7H6BA"'DC@?=4EA:G8)4)A!#;3C06?:&(29">=F<6/9E2.1<%)#7)4&;505:)?'<
@r3806
GCAGTATAAAGNCGCCATGNGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGNACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTT
+
'EB6$C!1(A&')-2'*025(;5*&!5#=(*6"9+8766-521"A1#HDE3C<,G*A6'3H1-*>:"<2F5H=4=&!>66499*=:'!>@*&+>+09+1?5;0=7)G@</)>H@74<'4AG'%+F/)%9$+';F,*:A(A.<$89F-(5(BHF#
@r3807
GNCCNATGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCC
+
%&"%%%$*+!"#$&#&!+!'&+*!'*"+)!!+"%((!&)")')+
@r3808
TCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCACACAAAAAAGCCCACCGGTTCCGGCGG
+
634:3H#H((C#"6F+)'5"1+$G+?1*+"1B;6":@1@(&$=?070$)#(E&4-<-.(C!"..EC/7#B=/G<=95
@r3809
TCTNGTTGGTTGCTGCACCNTCCTCTTCCTGCAGGCCCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGGGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGAGCCTCA
+
5%;"7,:B:!='0+@ADG*39;)83>64#?!7E>C#HH*(/40;;'/+>#34:;8B8.8E#BE;1+&$>HB1,B=(#/>+($<2(6D>@C@F6></G#9F2;=?D0E)1G!**/(1'<0.9H>><
@r3810
TTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCNACGAGCATGTCTGGAATGGTTT
+
*5:DF/%C-C6<G'3A>-;-68@G7&-6'%$$"1E<5$7A"5DA3*$B"#2A,6D1-0F'9?9(A6'"F.)A?36AH',!(,2.,'%+,
@r3811
GTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTNCGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAG
+
265.C,BCC6<95(:;79=;*7CD2<GD-,D8,(0/&C?'0@4C4H37*B$5)A#=*91F(72G"8?A"+5!+/,.CE*3,")/0F=08GD)($A3D*<AA51=)9,)16>&;AFDCH!,A7.71%D5C4F@
@r3812
TGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATG
+
(9:G"E!6%>4F668B2/'#;=;@2+*84E'GA1:'<8,;1B8B2@<DA:?%4).F2/
@r3813
TCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAGGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGG
+
'*.88+7B6/8A--3.'/5D$C;:0.818"%!:"E1.HA$DF5?*:1,;08;46'2G.=5/;9&>658:H'+-/989<
@r3814
ACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGA
+
42"AA"@377A8)*(."7(A:(>/2%";&#783.")30&59.@/"@/%:2A4,2?)%@86E'#"+'D3H("@)=6+>8&:B/?(>-%(;4;'84DAA!"#/>/C7,#E91:B1E)B%=
@r3815
GCCGTCGTTCGTATTGCCCATTTATCGACATATTACCCATCTTCCATTACAG
+
*+/'2DC878*,,?2C4@;'&6>C*H>@9-0%9&'2:4(FF%!+3!C?>,9'
@r3816
NGCCATCAGAACCGGCGCGTTTNTGGTGGCGATGTCTCTGTGGCATAACCATCCCCAGAAGACGCAGATGCCGTCCATGAAT
+
#"0%/+H3#.>GB#089#$*9H///@>.9(3$!3";+'&5$4,%4AGBB@25/,?/>)1/A>2#6>H'G%6%'"6;/.'07"
@r3817
GAGTGCGGTAGCGGTNCGGCTTTCGCGGATGAATATGACCAGNTAACGTCCGATATCACGAAGNATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTNGCGCACGCCTGGCGATGTGCGCCAGCGGAGTCGTGCGNCTTCGTGGTAAGCACGCCGGANGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGNCTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGNGCGGCGCTTTGAGCACGGTGTGACGGACTGTNACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAG
+
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
@r3818
ATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGNCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCA
+
C"'!(.-HGG-"'"74E8+'<E;'-@-7-@$2==*=D899,B805=D8;,92G8=#8<1?6'-+05>$<:B1,@=-$6*408E+&->6;<$A!'!*41D'0"8AA<F$(&&@'0#,D5!='BD*2682'F$$$E*8-D:*
@r3819
CGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGC
+
9#184.':"H;<!7F%:,7+B;<.*4+28H8G9>A:6(4#/8)!4$
@r3820
ACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATA
+
%!B-844&H%.922.6:#='&"1/>0A<H+<(<8C/<?-,>E("A;,,D@%F4:>102?723$159F,>/@5F1.2/:6@+)FE=;<7GF/:5+B-H
@r3821
GGTAANCNTGCGCATCATCGCTCGCCCGACCGACGGCCTCCA
+
(*')%$%$&+%#$"('*$$""+"++)'&#(+)"('%)&+$""
@r3822
CCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGNATTTATTGGTTGTATGAGAGTCGATAGAAAAAGACAANTCTGGCTTGAAGCTATCAAAAAACTAACTA
+
7=#;<356#=227%7&?+77,C<+=?&18!'(=?F2A#,.A=?28E9?*=<3$1$#E&2.4634/2<<7.:!2H%575@>-@:F9&DE."49>2#+3.5@C->A*,,4@!A9H,?*-8>$9=+E(<*<4@H!H/,;6)G<4$=$/71/6!*@=<<8*(0A4A'*3B
@r3823
GACGATGTTGAGTTTCAGCAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACC
+
)+)!*$%('*"$)$&$#((%$$&%&&*+&!!*"#$**"))#'")#+)%*))'+%++(*!+!+)&"+&(&#
@r3824
GAATTTTGCTGCGNGAGTGGCAGCGACATGGTNTGTTGTTATATGGCCTTCAGC
+
%++%!#+'%!*+$'+($#'"!"#+$*&$"*$(&*)$"+%!&)+"&*)+'#!#(#
@r3825
CGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCAC
+
G')+'$+23;CF?D/#+40:<?++0=D.3'8+">77?#8C>A/7(*H=FG';/#3B4-"(22:AA8F*0GHE493)C45552C*74BH'<9H/0D@C,)-&.
@r3826
TNCATCNNNNTANANTNGNTTNTTAGCTCAACGTCAATGCAGNAGCAGTCATCCTCGGGAAACTCTNTCCATGCCGCTTCANCCTCCCGGGAAACGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCNGCTTGGGCGATGACTGANCCGGAAAAAAGACCCGACGATAT
+
!'*)"*!!"$*(###!$#!$*$#+(#&%%''&!(!$"*%$++$$!$!"+&'#'*++(!+"**%(*+!$*#*"'#*)*(##'!#+)!($*#$"+"&#*#*#&)$!"&(!+))#("*%%+"#!#+("*)#(+"##!!)!!%*'(#+)#"(*"'&++%+$$&*%$)&'$"*$+%#*!(
@r3827
GGCATTCATCGTTTTTACATCGTCCTCGCGCTGGTGTAGCCATC
+
2*FC;$-E5>'521+/%7FF'7%:AC&/A5H/+D(AC9F>,184
@r3828
TCTGACAGTTCAGCAAGATATCTGATTCCCGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTC
+
1!@)?.25:0G69@2&+H/"21D:A0??802"%6+FEB4)(=#D*B+$)B84DG;5:"&&DD5B4A=43")="=2/./&2=3H<B+%<5H
@r3829
AAGAGGCGCAGNAGNCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTNAACAAGGCACT
+
F!;?'-.E.4=%G"G(?6/22A)%*C080=!3B(.50,,998<8=3'-=+=1.D@:$A7'B!2-$.D2'#@.D89/%3'8(:
@r3830
CCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGNGCGCCNGTGCACTCTGTGGTGC
+
F&FE'DF4C4HCF7<9*2D+56-!EF:6@D%#F8+*,$H)A=5>G*(:.+:%1$DG#H$?%-8D(:E9@'@?+
@r3831
NTTGGCATCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCA
+
)B#E(2(#"1$D,DH(6.>8C6'%,8/8593:B8@.H;+.0A/,DD4,+98>C-D=
@r3832
CGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGG
+
/$1#@5-<H;C#<;D(5:?:"C2-(7+#B4/1EE6E5&25#(!H=#>:=@/G2?.AH8B304-9D8572&-3.2??0D
@r3833
TTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCNTCATACATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCNCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCTTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCC
+
2FA&8D??F4%!B:0/E36.#:4,9741<#???.FC$:3+&E1<>E5-.9+8G2#%0)87:35$@4",#6;9=0%*.G0'A%'/98C13!:?(9"5(F98-:$3@(:.997HE-HH7$/)A/'G*%=HF5B$H9-@7H92'?.0:/F??&:@>@%0F;C4FC@35C*0.9-(4G!=6E<!"@&=::,?FF:#3"?:#$$C+029$6H'&*3+D9:D)/2>G.:@C9#)3"==G='!E%->A@!C.;5=)+9,B+."2>4>4A9;?,8=>:#GD78'&*'D?/2(<)6:3=16?(+'F++:>BE9337F#BC7$*41705.':C)B3$+2.,9B%H!)?3)5(3'F"
@r3834
CGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTT
+
*?DC/B!:FH+5=3">45;$G0<@40H9EE$8<HCB@/+("5(DB*20?4
@r3835
GGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTANGAAGGTGTTATCTCGGATGGGAGTAAGC
+
8+%"1GD:4C%!/,A,:B1!*?&5%2*,2=1>>=2#9$!=)D%G6AF.09D53G'!=;4"9G<DB4B.8(;&93AD.5A&$.7$"B2*"EC
@r3836
TCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGC
+
H5)8-46F!$FHAG*95G#"075'%#7%FD8F'!("!6*C8A2%D;DD4;G
@r3837
ACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGA
+
)*+$!$&$!%)&"%!'+!)#"##)&&*&$$)(!%*'&+*"
@r3838
GCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCC
+
/#+'1!HDG@+78E=)""H@",1*#@&0H%<!"*-9>9(C&0<5=9A#',()439@H4H
@r3839
GGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGGTGGAAGTTATTTGCAGT
+
+#+#*&"*++&+*++"$&!"(#(!*')((''%!+(&#)'$+#+*(&+'+&"
@r3840
GACNNGCGACNACCATTTTGCGCAGGTCACCTTTATCTNCCGCCACTCATAAGGCGGCGACCACAGAAAGGATTTC
+
%)(%(#&%)*+*&)#&%(*#*("&&')#+#")+&+)&&$$))%!!*&*!#"$$$)#%"$'")"('(%%$(!($#(*
@r3841
TTTAACAGAACATTATCTATCAGAAAAANGCCATCTCNCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAACTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATNCCTGGT
+
1+<82!#4H=)7*C97!,50&7:E<9>!%71,/!21'A,)8#;&2E1$&)'!E8H$!5()=*=;5;$9AB5B*8A!9G5HD'E?.6&DFE(81,/61?"@)E?+<+=B<&F:H92(0F9?EB*$='"A$$C-,&H7,H2278C>2&4B7@3+;%)7E!D+CBD2-9=<6#22@C1E05>559A'=+H;"80/51%8(8=;(#5!1!2B4-*+,@"4E*EDGB2G>)02;38"HCGF>1'BF(&-3*3"64B.<D6A#%H28C!&893>-*F
@r3842
ATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATNGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGNTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGA
+
=*E'1B0C41E>'>:E?;274+#6/',;.#3%!7<5D6#$<?E/0F8GC>.FFH+F!,04!-E6-/57'%C#HC3F@BA28(4"'%)2E7G*CA8@C>6+=A>9A(HED1D6F@/H?/=>/($>51.BB%!%2D1BCD%)DC2)5;=B-#B3,4A"@====1)@5<!H;B3@6=5?1/A*C$7=6C"G34GAHG"&G*H,4">0DC(#35&'5-H914F'EC10G$=4G-:&<0;E%$G:GG=7"00<H?2$.GH%@>-
@r3843
TCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTGTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAG
+
4@'@D=:#@>514:$&*#.9E1811$.,5;5)*HA;;=H$*/?(4)+,!+!1-!:@)9E#:8<8G;00G(7-2/*9F"1+-$>,G4$>B#%AA.&<D5<F+54#76265C;..&3>$-$?1-C4=F2F#?CE@0'4%AC7(%6!1.H7:@$@@20*88H,;+FA0%H970.<)"D/ACG(.D0H$95>8&@<4%,)1.2/@$3B3G!3)+!94#;CD;38B*'<;8:E"G3+/<@<E.?;1@C'E!8FA:5(!*$,3D+$3(1#2-&2?84=?G9E9?B#BH&!76/D&A>4
@r3844
GTTCTGCCATCACTNCAGCATCCTGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTANGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCA
+
*#A/H("B<2H3;50&E<$;,,?%;=G.B33;G,*1#$H3-!CB!((H.1*+->2<!=D?!(.G8&C@A-<EB,F=A(!B<7*":G63(@G6-*$>@@-&@D0=1=/HE9:3F-@7.#;C(0,F>,(.;EBD<5?:
@r3845
AGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCACCCGTTGTTC
+
@?.FFFF/E7,).%6;D"4FCB$.G3$(3G=556""9&';E!"/0&*-9:);6(25/A@'D-B=+7,4-','=)>'&AFH2$6C9A8'#
@r3846
NACGGCNTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCAT
+
"&%*%*+*$"$&!"''%')!%&+%!"("!)('#$&+#+*'#""$#%#*%'$$*#""+')$('+)"%+)%
@r3847
ACGCATNTANAGCTCNTGACAGCGATGCGCCGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGAT
+
&#(('"!&)!"*"%'$**$$*%'+$#+'"'&!('*%*&)!$&'+%#('#+)#+($(+)+#&#"%$$&$%)*(%)%$())$%!"&"&%%&$##%+(''##!"+'$&!$*&&$')#!%+'$!%%"*&)!%())'#'*#')!*!#(
@r3848
GTCACTGANTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGNTTTAGTGGTTGTAAAANCACCTGACCGCTATCCNTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGANATCACCTGGCTCAACAGCCTGCTCAGGGT
+
%+'"'&%!"(&!!$%#&(!!$*!'&**"!#'("*&%!"))*!"($*)+!*($*&$++&'"()'#+!'!'&'"!#('+$()!+""$!)))!#&)'$!+!&+)&$(!#((%*#!(!(((#*#+)")!#(#$!%$#!*'!**#&$#$'")(&)"%!%"%##&#""%#)#!%'+$"&&$)*%)"!#*%$'
@r3849
AGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCNCACNGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGG
+
2',C3!65H!1/1,E.2)2*9!5'E%067E;3(E&E@/EA:,846&14/GH@"E#;F3&#;!,@/-ED"-9,@%@A4;29&BD68FH+6.8.@-C*6HG?B4>??H=)?=2GB6#-:?8:=3C>0#%4F.?,4,>HF:9!"@*@$!%*AE?-0-BA!7>>72E(8%G4F-G3G!E?:</$.1H8,@6B;)6G*'E8/3-<72B;&3=5;7-%8AF@.B%/#H)H(!B8/GG-9G6=;$*F
@r3850
CCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTT
+
;608'F8'#)FA4+2,%B2G629?!EA-+-1$&/#1+;2>$,E%<)4=<.=.#='6A+8.
@r3851
CCTCTGTNTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTC
+
1?993433G7!?7$A4#.$3F8D+4795!=&(0G7>1#A$2GBE!A.($'"4+99+H#<C@".H5@C(1+B/)+51(/!#C'4GB3/7:GE,H'&F2E#+6H'+-D8;"41$=0")"<
@r3852
NNCTTGANTNGNAAAGCCCGTTTACCTCCCNGGATTTCATNAAGTTCCGGCT
+
#!)&#$#!)"'!("!'*+$)$#%&++!!)%"*")"))%%*%%)!")&+")*!
@r3853
GAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCACCAGAACACCTTGCCGATCA
+
C$E9F@C;4$+*@<:G1AE3:/D@-B)AF'8C>6F86E9"=@#!!/15;43?3&C:2C8?)8,&2**#FC..5E=.>@.+1
@r3854
TTCATAGNGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATC
+
'=.@94E#!<%+!+D2429<,"/9*7;5!68,C/"93B".E(EADE46''E-)@C.:/DH8$C>E0="(-4(D?#&F0!.;)';)E1"
@r3855
NNGNANNNACCGGNTNNNNANNNNANACNCANGNNANNNCGGANNNTTCCNTNNANANAGCTNNNNANGNTGNNNNTNAGTCCNGCGACTANTTTGNGGNNGGNTNNNNNNNT
+
!!"##!$#$"""#"!""#!!$#!!#"$"!##"!#!"#!"$#""!#!"$##"""$!"!!!!#!$"!"#!$"$##!!!#!$$###"#!"""#!""##$!"$$"!##!!$#!$!""
@r3856
TGTTNNTTNNNTGNNTANTTTGACCAGAGAACAAGAATAA
+
&''#&!)$!!%(!!%"$"'+$($)"%)&+')+'**(%%)"
@r3857
AGTNGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTNGGGAATGCAGGATATTCCCACCTCCGGTNAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGNCTTAAATCGACCAGTAACAGGTGGCCTTT
+
"*($+($%$$!'"#%%%&+')!&%$##**%&*$!$""'&"%&&%&!#%&%#)%!+)%&**+&&(&+*%$*&&"#'('!!'!$&!#*&)*(&+"(+%#*!"$'#%(#!)$%+*)(+&"!*(&""#'))"(+$%*')"*&()!&*$(
@r3858
CGCCGCATTGCTTGCAAAANTTCTCAAAGTTAGCGTTGAAGAATNTAGCCCTTCAA
+
?('B;10B'-"AFF!8;);F;F>#$+81H027&%'B>2G>/8"=C34!(DH9C2.?
@r3859
CGGTNTNACNCCGGANAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGNCCCCCTGTNTTGAGGGATAGCAATCNCCCAATTTGTGGGATGTTTTATACCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGG
+
')%'&(#&)!'*!$*#*"%!+&$#()!'$+)'*)"')#*%*)+)"(($&&)#%)%''!#$*!!)$)%#**+!*$&)#"!&''*'!*"&+!#&)&$)!*+)$$$)++$$#'!+!)$+"*&%"+"%#&"&)(*"&*$!$!*)(&#)((*%#()+")(!")$&"*#!&$&($+$*$(&%*!)%'#)!"%&$*&%$#(&#'$""(#+)#)#'%(+)!&(**%)
@r3860
CGGCAACCAGATAAGGGTGTTGCGCCGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTT
+
>2&D:HHHAD($*%1,C!C>'E5H8DH>E6+%4=#=4H5E0"#.;$7"0#1!&>F!&!,,)87;?&/8>?>3)#,F?=B>GB<,.'5.2#=+@
@r3861
ATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTACTACCTTCACCGTTGTT
+
$&H@8G:1H2"0/.?6".!?6H&H.))+;%A864&&",?&:99%9>0+6H4556&CBAC%>0,,2*1GF/.E74(5!+->@=':6@GGB'+&#1<,$(5;
@r3862
CACAACGGAACAACTCTCATTGCATGGGATCATTGGGTANTGTGGGTTTAGTGGTTGTAAANACA
+
/FB*1-,DGC0D13&B382H025&AF.$G#BE>3C8$2*'822D*=.0D?:B-+A)'?3G=<H7G
@r3863
TGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGANCTCAGCCAGAACGACNAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCNTGGTGTGGCAAAGCTTGAAGCAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATAATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTAGAGGCCGTG
+
79''FA@#98#:89E.,#H==2%/*=20C2ED2(4F7=5A#+4@?;38B#$#7EBF.F9-(!*C=',@00@.GA7&2F1C$;.->>=3'+".)4F+9E"6'B?8GD+)'+AA"C2<=A2;BEH*H<.#01*?8D:'C?;!;1#?F')%<9FE,,#$$3-F:8$@.@3=4/#=."(2EF-E*!A#99(5$6!BA3"/"%E.+;-++&=;;3$=B1-1/?(B94:)%47A-9E,@G*<"%?E':CE0)C2+54.;13:&=:GD'HA%32"%8D4/<1.-7'>5%:77=%"5!;7>75*&:D+#G
@r3864
CATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGC
+
D5-8><=6:037H1?<5,7(6H"(+&D/&868";@*).AH?%;056B-A48A
@r3865
GCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGA
+
B">(')4@)$>&;!1%'=+;#4A8=4#,.>9<-)D"+/(.,C?D$("4%$36!!#B45>+E=D!,%.0:,AG#0F7B6H)2,G@3<07'$1;5D;-5%0677?.BH1(9B
@r3866
GGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTA
+
BBB8A%$((CC":4!DE39"?$0!@4-7-><E*'2C8=9-=7.5>45C05>@!:<H%>$&#;$36-A5</'6>-C!+)5),+?*,=0,AFG#5D:,.(@3)0./3CD%
@r3867
NNATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGG
+
%$3?B25C<A4;8F0%B0&+D#!9*(#HA3A8-$@1!!9648.A#2D:E+&(&D?(41?=2#<>8
@r3868
CCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCC
+
A"8@(0!!1D;E"1(*D,'7-.>0()=-,9*)G!1!,&-A=+FD?79?F
@r3869
CCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAA
+
45G5%=C6"(%?<A3E*=@<4H(1HD24=17B/FEHF=A?$BH?:<22*;/B>(+*59
@r3870
CGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCNGCCGTTGGCATTCTTGCGGTTGCTGCTNACCAGACCAGCACCACGCTGACGTTCTACAAGT
+
D0$F48G='41%2A@':3.A?&FHEE(5>-0;/;%D#E&'<'")8D''D36/(.-6+(4-/(A.FC/A4A85%.#C7)$0+3()G03*(8#/=A-G&$<?F/6-*,6F.G2='%'.0'F5%G2)?5>E2H)&+3C?B!
@r3871
GGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATG
+
+/4;8#920"#;(A0<!'$A*$:*H$681;7#'+,#0A898CD#
@r3872
CTGGTGGCGTAACGGCCAGAANCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTG
+
-*DD">B3!=(*%;?$4C$0)8F::-:6$+195A&4D6-/!-;5=6,D<!!(6A?>3=FF'104*E/'5=H)5++==#&18*'8D2@0B7'8!=B)H
@r3873
CACATGGAAGGTTTTACCAGTGGCTCAGGTTGCCATTTTNAAAGAAATATTCGATCAAGTGCG
+
A8>G-EBB+&C-):>4>&;B':H"H6H!<0-DGE$472"634(*:@7>;$8::;<@E$+3D;?
@r3874
ATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCGGGAGGATTGCNGCC
+
9AF)>%/6D;8A65<"HE.C/:>">/"E94%8,+'),(<?)#'?71>%8*A';#$;8
@r3875
GTCTGCAGGTTCAGTGAGTCACCCGGCATCCGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTNCACCAATCCAGCCGGTCAGNCTTTCCCGNTGCTCCTGACTGTTCGCGCCCAGANTAAAATCCA
+
3'2"B6@F<;("4E;1!6=<E"9>A2CH;D/+>'49*.1>,,DB#0(+4B3,$EC&FF?!:EA#&8CC458?9A%%?>(=0:/<-%+1F-1<"/54.E7H<(%!E3.15(D8'6;F:C)9G>,%D('")C.$,,0GD$3@5=,(F8"8E%A,%</E
@r3876
NTTAGAAATATCAACAGNAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAAT
+
!:685;(2#,-<&;F7H')%HE)C)(.5-7G?<H85:G2*F4$*H&#/4*@($F4HF#216.996#7(#B(<
@r3877
TAAGGCCANCGTGCTCAAATCNTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTA
+
+:=9&/%15"@E+(&'GB#<HH=DCG769.%@163B"<79#4(%5CCF90.:>19:3@+
@r3878
CTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAA
+
H%'9B!*3;5D6,5><#*6&<9+FC*'&9.,6?A9CG%9'::%=(E;D8H=%E
@r3879
GTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCACTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAAGGCATTGCAGTAA
+
6G,''@:96*>>@=$D&63798>9@@3H2A,82&2#=,(*>!708*.A<@!HC'8#@E*G4<4<1(24+2170/2FE$!==35&$'G(!G".<,3&55$F"413'.,!><!05H0/(@697+9;49C4#'0G<?3.::EB*D5$)%G>@,4!0;08-8:+E)8#?2)B0!"2/8>6F51>"+15$+4E9*H4:>;B@(=G=)D7-=CG/!21.G*!#F#44.'&<3=<+8E<)1!@?7%*6&+$7>>FG&8D%C*,5)$5.3@
@r3880
TCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTT
+
34(F::G@,8H,G51G02#7+(3//B3?8%G4')?E<:7/).,:*6E/D!$!!&"D!H)?:@0<@-5B06$7AG5(:6051>,1?C1.>
@r3881
GTTCCGTATNGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAATACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCANACATGC
+
?<@?2.B':>97)@.FEC<*C0;*20F?!$<.1E&.&8@)?:6%9H*7=F!;AD"?,C""2F.7&"B.;0-+.B$90;*;(>5#:;?(12?703F/-<HC&"0E-@6;6511;(+&<"BC01:B80#1>E+>'9-!%'H'105&EA>AC/@&':@-@.G:33A)*5"22@<A(5DB.=+1./"HH9/3+4>?FD:"9>
@r3882
NNTTGCANCGATTTCCCCAGTAGTACTGCAAGAGGTTCCTAAATCCTGCATGTGGAAAGTCCTACGGTCA
+
"$*'*)*!'$#!'%+!&"**%%#(&%#*$(%$'%*#($(+&"#$("*"")$*)"+%"%)*''(*%"&%%&
@r3883
TTNANGGNGNCNCTGAANANNCNGNNNNNNTCGATATNCANC
+
!$$$!$!"""#!"""$#$$$#"!#$#!!$!#$#!$$$!#$!$
@r3884
CGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTCCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATNCCGGCGCTGCTGGCTGATTTTCT
+
C/;$,/-G<@$4A:9E<C6;>+HH@#+&@?@0<E4C")'H@31FH&=)"2$2E0@(9;>@@=>#?!9G9)@5./;A04&C("%!"AGH<%6631-'$B@*+6D$9;8+6G0%(F$D:9F8"56#C,'/33C0*9@)>?'/G);<;>&7E54261B-/0&;;'
@r3885
TTAGGTTGGCATTCAGCCCGGNAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGNGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCT
+
$%7+)G+-AC=-=A&#F5D93*4@A:,9('/07B;G$4D)+53&-=<9(DB89,"(/F<'61(>$9GCB1<<G5$A:9;D9D6('5"6@':91#H33$(0C;,!$);(/@-)-&&"H'C%/A)*-:&#A&6?22,9%+#9=$;;16*A+)E8%)!FFAB@<5A03>7A/432+$1E*,:+?0*;'-+D-%-!?FB&B1%3-$29.00A;;*-2A=?)B6"F+E;<%*F#ED:+/.2$(--:(DA*8@C.,+94E<-4:)-770(6?H>E#1(<41-!)E8G7;96?C%,:"G)9+F&8&!=$G!>762>H
@r3886
NNNNNNTTCTNNGANGNCNNNGNCTNGNAGGANNTCNNNNGNNNNGGGTNNNNAGNCCNGNNCTTNNNNNNNANNNGNCA
+
!#$#$#"#!"!!!$#!"$$!$$"#"#"""#"$$"!#$$"""""!#!!$$#!$"#!!$#"$""$!"!!!##"#!$#!#$"#
@r3887
GAAAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATAT
+
%*"(+&$'#''&###('*(&*'*+*("!%*&*!(#&(*)$)%()*%+)(#""$$%+"*%*&)"(#+")&*(
@r3888
TGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTT
+
0*H58"<E<0!29'04:(E;$#B5:9(5)$:G0D1="(")8(9<.3F
@r3889
AGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGC
+
"71(<2&1=#:*D?6,E$>)H32E?#*0'?1";CE@24?A
@r3890
NGAATCCGCAGTTGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGG
+
#1B0H;64&:B?H))""CG=?5-#/&+*G/.>3:H19:6!#,(4+-=D+0C%9CE?;>?/=:('/
@r3891
GCCGGGAAGAAGCATCCATTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGANGCCTGTATCC
+
.(HA9:<<*&/E+H0B0/-#7:-C*=,,6+A6(3DC,5*(&66F?!)6E5C@A5%E:=33>#:6:B6!,::8?@@&EC>D8,A-4&2->&.1!3
@r3892
NATTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGACACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCATCTCNGGTTAAGGATGGAAGAGAGTATCTG
+
#+++0ED>C>/=>+3/>98;.%4;7H;7>=><2F>?'C-H1?+;-%3=/7E/6.H('DH(1CE")@=7&+<#1A&16G+C41/69>07=(0B2A8>8:F#0"#/G<>.HA#0DDF5C"-*-)$A*F.E$4E-E:
@r3893
AGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATC
+
5,B=BA'56#7;5=<<#"!C*<&B64-2108"(:G#5.D38CH*'D0B4/0%>9!2C"6A4.=A6)8*5*:'!
@r3894
NTACTTGAACGCATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGA
+
!<<5;G;@;9F,>42?6<2!<:''5@9/$3#6=*.&1C<@(H!?6@53G8%;'D&$(B"3#%#+D?5*FD$74:FD-&C-!.3#DH!(+2C;#$H<"6#F<&(0C@'-(%(DA07>&;CD5F=<,$?"/7:-;"23+BB=(5&?
@r3895
NCGNGNNAGCNTNNCNTGCTGGANTGGTTAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCNGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAG
+
%(*!'!#)$#!'(&"""%*'*))"&'$'#+"%#%%(*$')*#%(+"$*!'*'&(+*'")#(#'#)))&$$%+('(*(+'$%!$$"!#)'"'+(%*$*!'$(#"&&"(&!$$%+($(*#&#+(%#"('%'+$+($#'$'!&)!+)+$#&$'()$'+*'%%!)&+"+&%*'$&+*$*$(*)'$+'!'!)*(*(&&%+$%%))%+$#*(!""#
@r3896
CCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCNGAATGGGT
+
>CE2<B(&*89F>&0BHC#A863D727#A2(64'4'D+<$,)EAA(;C<7(4#!%/%4!<'C-;!5H9EG7=!$0@A/:(>.+*+AE2.(4=35$)'787%1$>"*$&247=:5:308$
@r3897
ACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGG
+
3&D".'<253%*F@H,>5$?=<4"H(HB/-D/,!",7<=)3=9
@r3898
TTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTT
+
D6.+B%84+(-+)=/18!%<,22G=%)05%/B#=0"'6(F#6G:%D7%8FE5'0G.A.2#F0%%
@r3899
TCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAAC
+
A1A.)<&0="62C0/92?/-?*2;5HB:/:77,FH8*D"A@
@r3900
NATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAAT
+
!;/?G+!=4D<):-8<=1&/6$6*F3&H>BH41&1D02)23>,>3?D/9(7#13-,0@-+1%@&/01A?!HC%%7(0>$'#F
@r3901
CGTNNATNACNNTATTNCNNNNNCNNCGNACTCNNAGNANGNGAANAGNNNNNNNNNANNNATNTGGAATNNTNCNAANGCTGNNNCCTNTAAAGNNGN
+
$!$!$#"$$$#"$#$"!$!"#!$$"!"#!!##$"!$$!$"$!"##!"!"$"#""!!$!""#""$!##$$$"$#!"$!#!#!$!$"""$!#""$"$"!!$
@r3902
AACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGGGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAAT
+
$+(!%!&(!*$#$)"()&"''))#'*')"(!"$(!#&+*'(*"$$(*((+)'$!)((%"')+(***"$&*)(!'&#)#!$("*!*$#'+&'"+$'%%+($"%#(*#(*((%%'+#++))!!$$%%(+%*#'"(#&
@r3903
AGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTAC
+
87H&2B/#H?H-GFC,&@943C@/D-23<A@,C.>G&?:1
@r3904
TGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATA
+
))9#(7"6&A::E/,D2@?F.)<!FBB+,+<&/54)!98?5(;>>>-E!$EG"?F*-HGE8.CF??-4F',7)F"'-#=/>4%HA?+-<+128!?,*9>?F!,?G.0@CG-).!G151:5%=-/4A88%7<%<.93?7
@r3905
GTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTNGCCGCCTGCAATGCCCCGGCTTCATCGCCGGA
+
$;E:AA::7#9%?'9&96@G-.4)0=B/300:)E6FD?$.H&43'FHEC=FH?39=@:9.%33H#!91
@r3906
NTAGNNTTGCACCAANGNTNGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATNTGGCGGGTTATGATGNACTTGCTGCTTTTGATGNTGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCT
+
!#&*$())"')'"%)$""%")+&'*$+!)&**"#*)')%'*(#)+&#+("'$+'!))'&)("(+%*'()!)"##'#!'&!#'&&')*""($&+"(!+*")'%*$%$)+(*($*('*)&$*&+#'#($#&++#+*%$&***()''%#$$)&#*%+*!%!(#*#&!#)))$%
@r3907
CTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGG
+
6;$0D):!868%#23EHE7'5<"#)$:;4E0*C1/9='!H5=)1
@r3908
TGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGT
+
;08?0153-<&C(7-H+/9#%*F1;@!"E>G77F-9AB:43H49B9)6C/
@r3909
NTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTC
+
#?F%("F9'$4D<6H$':8>/'90<.!/0-0C?;"#EA'5=.'C)>$B8<(675H+./FD"."
@r3910
CCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTCAAAAGGTCTTGGATTCCTGAAACAGAAAGCCNCAGAGCAGAAGGTGGCAG
+
2*+@G;2()&<G.:A?F=<3)@AB$1),@".5F>)";#=H%BH7.:<#D><59?<2>,-CG(14',<9%(-6H,"8'$4*%=>4.)!-$9<9H*:,$C</C'!>;?)2+G2-$@E9.7D/&?3'650:;$!05!B'G'1!?)*7%!&&18@((7FEF'C@$+7.-#A0'>-$$!+;(9!H3
@r3911
NCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATNTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTA
+
!*$+**(*))*+)*"'#)(!)%"$$"(!)(#+)%$*&+(++(&!"*'(%&$'+#*"(""%$(!$"#++!)$%!)*!%$*#()%!*'$(!%!'+#
@r3912
CTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTNGATTACGACAAAGAAATTCTGGCTAA
+
G>F1'B-'=%'#G!97D%H<92!28C%//2=!8,D0<3B!"+7!15@71970"'#""5(G4G4
@r3913
NTATCGGGCGGAATGNGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCATAAAACAATGAATATCTTTTCTNTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTT
+
"4<HE:&;,8;1(*1!G%<-!?+D7#$6>0?.?%(9F4+7#&A&,!G2(29;=CA@8F7<)#/.;.2@0H(1(H9*)+=G=+-91;"D%B(5';5"+>=9.)=(9/.*@2=9<(-$;#?=755=&CA2301')E2?@-069A='<0,>8B+=B8&&CB)8@
@r3914
CGCANTCTTCGCTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGT
+
))&(!+#""((%$"!#+""+$&"'#''$+))(((*)(#!++$&$+"'%)+$++()#$*%&#&!(*!*&)+%&"(#"'*$+!!!%"#+#+)++%&%!)')'$'%#"!(*$)$$')!'(")'!)'"&*!'#"(!!$$$#"*'*"('$$)%(#*
@r3915
AGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGC
+
B=E4D$4="(H*H.>5)+:%4,B8;,B)#F81)75A8:C*+4
@r3916
ACTCACAACAATGAGTGGAAGATATAGCCTGGTGGTTCAGGCGGCGCA
+
D82=A%:"0.+>C&C8:9;E412)?",H%-(GB"%1,33&+(84B8.%
@r3917
NCCNGCNAGTGNANGCTNTNTNTANNAGANANCTTNCATCCCNTNNCCNNNCNGTGTNCANATTGAGTAANACTAGTNGGNNTCNNANGANNANACGGGGGAANCTNAANCCNGTNNNTANAGCNNNNNCCCTGACANGNNCGTCNCNNNNNGANCCGANTNNNCNGNNNNNNANNTNCANNGNNANCAGNNCTNGNAGNNNCCANNNCCCGNNCNTNACCGNNAGNNNNACNAGATNNTNNNNN
+
#$$!$!""$#$#!!"!#$"!!#"$!"$#""#"#!#$"$#$$$!"!"!"!!$$""$$"##"#"$!#!"#"$##"$!$"!"$!"!#"$$"$!!!##""$$""$##$""#"$!$#""!""$"$#"!#"#!"$!!!$$$#!!$!$$#!!!#!!!!#"!""###"#"""$!$##$!$"$#$"!!#$##$!#"!!#!!#$$"###"""#!$#"#$#"$!##!"#$""$!"$#"""#$###"#!!"!#$###
@r3918
AANGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACC
+
7.%!4/7?=&(2341->*@&62!.EGD+%(B9.';BD#24(3?+>-.2&;C;H#*%D;'=21*?0HD@)8GB1$5@!5;6<#$G'&F?HH2<>)06B#,&0''><5(=(4&042#%-3/C?<3D$B9'(%+H>6G/<C*H#*61*1'>C;E!<;A)?A5-"DC83!2C:6/"3E25/$F4&;FE7E;01AA?1!@;9CF)"%;=5:+-:8@@'"C#:6+7>EB@G;'!--/;6,/*B!.#,1?G>@,+2;()#%),!91!)<3;3&".?E+G=AB94GA=)34
@r3919
CAGGGCTCGGNNNCGCNTGNNTCCATCCGTGGCTNCACGCNAAAAGTGAGAGGCACCTGTCAGATTGAGCNTGCAGCCAGTG
+
"*!&%)(*#!*(#!('!$$$%*)#%##&'(("!&!+%"'&&%#!$)')'*%"&'+'#"(%+*(#!*'$&%)+$!$$'"+$*%
@r3920
NCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCA
+
!H$522@H02FF-*7DH6>>;));AF/1?8E/?4?0C20D<B4;&;<?/".HB02/??%4;):3;F::"(:/E:7>?E!3!?B8
@r3921
CANCNANNTTTCCAAACTCGNATTCGTCAAAGGGATAATCGGCGTGGCAGATGACATATTTTTTA
+
#&*'!!*+')'*#)#%%*'*&%"$)"'+&!')&#'''&)#"&)$*&#$"&'$#(+#"+&*(%&)*
@r3922
TNNNNANANNCNCNTTAATTTGCGTTNNAGNCTNANTNCCNNTTAANCNATCCNANNNAANNGNNNNNGNANCCCNNNATCNCGNAAAAANNGCCNTNNACNNANTGNCNNAACANNNTGGATCNT
+
"""!!#!"$!!"$"$#$#"$#!#!$""!!!#$$#!$"#!#$$!$$$"#!"##$#$$!$$#"$$$!!#"#$$##$$!#$!$!"$"##!$$#!!!$"$""$!"!!"!"!$"!$"$#$$!"!#!"""$$
@r3923
GGAAAAGCCGCGCTCGCCGCCTTTACAATGNCACCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACNGTTTTCAGCTATCGT
+
+=9H6>@2+A=23':58/!A;GG/BG37*=17>(&5?7C.D<):@;-(C-+&?(G,,#G,*B$#$$G6#&H-:.H';*),33,C%%>5-
@r3924
TCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTC
+
H&:9$$>HF-,)+%G#$(7GD.G@+.2257+DC,80/,%+FF%:4$C-33)B'
@r3925
GTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACANCACCGTGACACCGAATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATC
+
%).5/.4>@7*AD/=#G$-?C-*2<:&/3C-B,G(><12+!.%<5%6$13?E9AG3%:D&")+:(9?,3#(&-%?B7+H-+4/<C(G/4,&08&;E$%2DCAEF!48525'?0?:263(!:)303'GEC3F;38>%+,>C3;%G4*G6A*?%%>H7->:G7&,5;(D57>0<G3-!/(F$43*=73##A<!(#,*>FC8)<06AA%#%4CC$=)!'F?<1B8C6,-':4
@r3926
ATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGNGCCT
+
F"3@<)*,7B3>!-93A>$-:1?7),881+*@<"3#%=4+%$(BE)(1$/B1F9?.7C)"">EED/-:/7##=@FC'#/'+4:*6#>B<(DE91=@=.3@"G4E)$7
@r3927
TACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGC
+
-92)D%E$*:G$*#87398><A0-%%AA/-1,29G,E<7+%#1,$"'4-0!8(&A<8(14
@r3928
NTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTT
+
#/"BA0,:G89C*G*AG)E3C1,?&A;/<C;7A:5@*&F&F!!'A+!5=F.14.65/3D5>/CH4/:#92A6*1*=,<;H)@82(05&:F(,@?!!%%#A:?<"$"#5E$)-"0$)C'%<*H">B946(-D+9/3G
@r3929
ATGCAGGATATCCGGCAGAAAACACTGAATGAATGCACCCGTGCGCAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTT
+
B5"(((!.9=)49.*3"8,4>07-*!>E"?$,3>48F7(B7;)2A-E(*.0C97:9D1)"%&6!;(.,'=.:;E/H$CEC$<CHB"4'<90E1D*E"%.;,$+(<F33::C
@r3930
CATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGNCTACGAAG
+
7:43/>"@$.G1.(;*;$-*>":AA19!0%@@()4#E"-*/)E=?*0@-G?4E(@";F:8"*H:0E!=+-6:)E''7GC-9&6CD8
@r3931
CAGCGACACAGCAANAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCNG
+
D?AD-")$#)#3)9;<(/4=5B)E7G=;7*>3@;&8A%//,,D;C0=,+DC+&'74!>%8%%)3=$:#F1!#.',8E$86->$4F(F+G%952B-)HG;C
@r3932
ATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCCAATACAAAACCAATTTCAGCCA
+
011-E<,(E:21#0-*3H$6G'#8:G;7/E/C*B3-0')7-!+6(>8E7GD7#=<+D5
@r3933
ATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCAT
+
7+H=F%C3.4C::*748(3).=4C?.(4%DG'B3360!F/;".@740'6FB<,4)6(BH/
@r3934
AGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGNACTCGCGACGCTGGCATTATCCGGTGATGATTACGGACCACGACAGGCCCGCAGTTATCAGGTC
+
"68/GG1GED%-+0.;<!G-C3/*"$34+6F$BE""C=>;=3"B:@%<+D7*<,6387D#!(BB7/#/$5)HGA4<*1A8!3%D0>DB-)EE:H#86.0*'<&
@r3935
CGACTGNGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTT
+
+$+#+')"'((")&+%!%%)"&!&"#*"!++'()""*#&#+)+&(#((##%'%"%*(+#&%$#$+('$'*#&&&!%(#+#'"&')'#!)"'+!#&+%#&*'%"#**(')!
@r3936
GTAATGGNGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGC
+
6<F/7354::!?D"&74'81-EB*104=@H-=*5G06+#F@:*H#-;@9$<.5(8#A8:
@r3937
GTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTG
+
9+.$92-5'43$,5$AD'*;0H2.7?C;E17G747&13!@2.9!G?D@$-8@:3F=+=?'B7FH!B..G4A$".08A?0:>49H
@r3938
GAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATG
+
F21-78AHCF+B(48CG'@6'0G5B@+9A&82:&%F06=.8=E7/79B#&$C98+,1-?>0F/8&G5$*%-$9?H!5E89;-&8E2
@r3939
TCGCCGAGCAGAAATCGCTNAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCANTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCANCATANCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGGGTCTGCGGGTTNTAGT
+
6D<#?E!6&;56G#*<><9A@.?75/!G,4A&&5#C<C%7E;)+?@$63/5/B+@-/D<)0*;'*92,(F5H030><("7:;?D4+-:H!,@.(+?H6B7'*C'D-;74)B67((!(,B:B$A'E0$H1-FH=E+/@4E%;;G>1@D+H8,%&"/4<5"C/'53#(C?02F)?-%C+>;DH?1"F4:*#)==G/5=C55H?:=4448?79C<D&?2/;<9!E=7?.(AG*?H#E%'%.3;:7!->"E6=D);=>$)4,%7/>HE!'*;:/;.%6!9B7/'=F8="?D80GDA"C
@r3940
GGATACTGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAAANCATGGGCTGTTCCGGGNGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCAAGTAAGCGA
+
;0?91&35H%@DA4/3*2+7A0/&:06:A?6>/AF&71!@)AD>9+,+F+A.H!G;.'*G$C23!D*,1G-$A635D=;$%>+):8%H-,&6B:?':$"!79+/'*-FCG+,,>#'88EH24$?H?/
@r3941
TTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCNGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAA
+
'CB4%(=$*.'FB67'=,C5?,FFC$8>9"2*+;).@;62$CG2'D:@6<+4"!"0F;.>)H0AH5#@+C";@:$,=,GH=%H,>2#54<;8@?*9G7F'#E:/550@
@r3942
ACTTCTGTAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCA
+
A6G>5A@'')EAEF)70H%E=C*E2$.=7)#5;!72.C%0../-&?A4$!"1"<6GE"@9*5!+2."5:%
@r3943
CGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCA
+
BG#=3>E22B07;8C%(#&8E6E+G5F.2/4:CH1$!@&!+F&),'FH038!4"0;.H::72D**?&-8$CFF(8
@r3944
TAAATCTTTAAGTCTTCTTTCCCANGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGT
+
G0A2/%H6+#2#E"4=7<4H#05>-6;'1/!<'>A7&3!9'/+G$-?!+6-,!.E)=>#>(
@r3945
NCNAGATTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTNCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGA
+
#&$&!(++*"%)$((++#)*)%*%!"('"*!#$("$"%$+'#'+#$&''%$(('$+##%!%"+%##""("'#'(#)#!++'%!
@r3946
CCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTT
+
(4F/H=E.(/'9$=085",'B9,G3;*(+""%&?&?C2GA:.$"H)*?<F%/64<@',>-HAD:;#!!,HAD+*H(.<@=:D.CH*>D$B(6,=7(F,G?0B>/6+8'19B!=G-!(.GFF1)&(H72%F#
@r3947
GNTCATNNGCGGNAGATATANNGNCNNTGGGTTTNCAAGA
+
$#"#"*$"%%&'!(*)%(&&!!'$)!"*)$&%$%%&))"&
@r3948
ACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGC
+
C)8G9F;;+5=/%")@C('-A5:;?"9@))>D(8F/*B&+G"<!+1!6A()78A).B,.E*<=
@r3949
CNCCATTCCAGACATGCTCGTTGAAGCATACGCAAATCAGACTGAAGTAGCACGCAGACTGAAATGTAGT
+
"(E+'>?4:-EA#5)>F25C".3-5=25.&F*&>2'873)?%F%2&(7B81).B):H!D=<#$''448$-
@r3950
AACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGG
+
G&F$,<H=(:A55!CGE0*3<.BC?(=<1$*H$'99"85EH9;&FG98615.;$8#<9+";%5241FG-'26,H8*62F254C-*>:0(:/#A<+#C87<'FAG<>%AC?"$1?:GB?9B2>FE637<2*78"C5A=F5H%:C$)H>HAG>%C:/0BB81/(7=D5:9'G&*<2,!1*0)F3&8A&$C'*7B9!5-8?D6.;8@9%490!-90*8C2?,1D@(2G>(+14?;3F7<
@r3951
TGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGT
+
FF571774E:AHBF1D9:F1;"E881(G&0DC'*!27!=7$&+F*+&?4CB.!FDGE&EC)/@*>4AF78AF@(E;:2#-(
@r3952
CTCGTTGCACCNGNAGANGNCNCNGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCA
+
))(#"*(#&$%!*"'*))"#)$%&*(+($"+(#"&()+"&"!'++")$*)")&)+$%&#(%())"!"()"#''!!"%!&*#%"!(((*$"(!"*)'!)*%&*%&$++#($")#)'""&+)'(%#""&'!!'%)&("*+%)
@r3953
TTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCNAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCNTCCGCGATATCGCAGNCGGCGTCACAGGTT
+
7)@'%.'7*52<H>66!2)CD/*%05&A96A:(;)&FG8:H!%33&0<+3"%*7>,(+1+4G"#7)7*>0+>%<''-A:6A7;24"">=5G"5;+E>7-0%0>0-5<4>3%D4%$0
@r3954
ACGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCTACTAT
+
#+$'(+%*)!#)!*&$#""%"*$*+##()!+($$#%"%!*%$!!&)
@r3955
AAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTG
+
9<8CE#>0E)@A.58:!)!(24+!5412H'FF<E!>)A,-ED.2$4--813*8?4C<65C>1>+D;3D2-
@r3956
NGGCTGCATCGTCAGCTCAGGAAGCGGCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAA
+
%5*A82))8D=9.;:BD'58B/0/;BC0FD>"=5:.6!FD1/2D.8-,)7D'8+*!B>>D!#,:*!6B/>$>
@r3957
NNNGACNNNANANNTATCNNGNCCNNNNCNANTTNNNNAGCGTANNGGNANNNNGNNNCNTNCNGGNNCACAGCNGNNNNAAATCTNNGTNNNTATNNNNNTCNNGNANNTNANNAGAANTNCNNANTNGGNATNNNGNANAGGGGCGNNATNTTNGNGNNNTGTGGNACNNGGTNNNCNNNCTNNNNNNTGCNNTANGNNGTNAACGGANNNGTANNAANNCCTAAGGNNNAGCNNNGNGANNTCNNAGAATANNGCGTGCNNAAGAANGANTAGCNANANCAACTNNCNNNCGTGNNTNNNNNCNGNNNNNNGT
+
$""$#$$##"$$!"$###"!#"##"#!"!""#$"#!!!!#$!!$#!""!##!#!#!!!$!$##!$$$#"$#$$##$!!!$$!"$$#!!"!!!!#"$#!$""##$!$!!!#$##!"$$"$!$!$"##$$##$""$!$$""$!#"!!#$$#$#"$!#"$$"!$"$!##$#!#$!#$##$$!"##$!"!!!!"!"$""$###!"$$"#$#!!#!"!#$$$#$$""$!"##!!$$#"$$!"#!$#$"#"$#"$$#!#!"""!$"#!!!"#$#!!#$!#$###$!$##""!#$#"$##$"$$!"""#$"#"!$"$"##"$#
@r3958
GTTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCC
+
#F7B+0$99*H2'#EG25>+;7?4!?'D5;741;;100?%.D<A<(*<-9-E@4A$C69=#8D90FF79>3)
@r3959
AACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGGTGACCCATCCGCGCT
+
:>5/#7%>6C?0@!0D"(E/,F"-H&A,8CC<H-:,B=)A,6G(84,5=H#A@-1<@:2*
@r3960
GTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAA
+
F*496#2"*#(@=1,0*@5$3?!!'>C%.@F%9-!A%;6*-:5%5C%>&@3:#**6=:@(63A98,65:/!6
@r3961
NATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTAT
+
!/@<B4(B-*<64F"!F*4!(&1/0.2FF?<3C(<D81-5&<<&(36*D*@@G-631B2&3G<%(2=A:>1E67;2<:2C>,@
@r3962
NTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCNCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGT
+
35.6H%DFF1@&.,H+7"!D$?#6(<1$H*'8*&11H1-'.@'B0!4B-$$+99-&%G$=7-6=D78A79=(0.*%:5H?!3+%,=C-6H:?-?:+C("*0,!&EC8#7)0*4G=H63#(>E+H*0$,@"5B516#E:3.H5,1+,<A%F&)9/H;
@r3963
ACCGCCTACTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTNAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTNCNGGC
+
,":4*D7/H/)<D9*,-AG6%"#&;44@"=B5'&FB>*,H0"11?7*#.-H#5%=H.<#*<F9$G8.:64+#;;4C?5@(+&#+&?560B2
@r3964
TGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACNACCGACGGTGCTGCCGTTGGCATTC
+
AE?=7H>5:;=51:=4&,)-2%!,2=*6:,FC4#=G?''AG!/AF&<#%7C<@):3;:;$'2E8)1
@r3965
AGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGNCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTC
+
BH&$H1GE49(8%C4<@A$58@@*"09F.G:;.H"-#<4+(E'-(D6$(7!062#:G&=$47H?-FGH<%23"$-"0%.*(+=1/2,B22/0G'5;,!.04F
@r3966
CTTGCAGGCCANCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGNTGACGGACCACGACAGGCCCGCAGTTATCAGGTCA
+
0#';F<;C7B,H6)D7(;"7F32:#=3C/<":7?CF"0:"1AE83<'9$/%./9#9?1&H!!@+3+.4@F,;7#+<0<08&<+"+4+=3B"&=0<9#$*#:>89E3)-<09?);#B;361?"4?<,3)178!89CH
@r3967
NNANAANTCANCGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAA
+
!!%!'!$#$(!#+*"(+'+'"&)(%!')$!$+&#"&(&%+!+++!!(+()&&)"(+)%))#"#((*)&'$$'(#%')(*$!'&$%*#(+*)!%%$*)+*+)(#("$"*!'($"###""#%+%%($+)!**(+()')!
@r3968
ACNCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATNAAAGTATTNTGTACNTTTTGCTGGGTCAGGTTGTT
+
*'#$++%**#)%('+""$%$!"%+(*&*&*)"(!!#'!%#%(&(!)#")()$)$&)*!()*$'#'*)%*$!'$&&!"%$")+&!%!(#$"")'#'&*'&(('*%$($')&#*$#)*#*"&!*'((&")'+
@r3969
NTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGG
+
!B'F@+A"39-66:(7*4(BF-%#!;GDGB/=:+&3F8';*4C;:9D(/$,91/?*FE2H58&1;-#AFF'3FE+:3"B-C$,1"/A!($'3%4.H:0$$>%3:A
@r3970
NGCGCGTNNCCACTCTGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTAGCATGGTGCCGGGAAG
+
#(%#$'$!"*$!"&+"!$!*!!(*!%%""(")&'$!&$%")%'(#''')&"(&($%!%"")"*)+#*)#+$+
@r3971
ATCNGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGG
+
*=9)6!$&/.2@FF*%!1FG/1@:%F;9/F)B-1(>8+;,F0E+.&=.26;!C@$A4@4+4.!>4)&34*BHD0>")2B*&33)3.1F/0-$=G:-/5E!5&-0D8F=G60/@D>8(?=2%
@r3972
TGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGNCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAG
+
/=*3*$:H)5'$4<:6F./1)0),5!A7G67,36&#=3CG42$E05;62)=3:HD?,9/FDFA-*FA;)<'0<,D?F?7&FCC5()3;5@-553$?%@/D0GHEC/<A*$/=
@r3973
TGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGT
+
AB+-/,HH=55E&<6:G77F+@B$472.0+E3H=2;4"*8)*CE"GHD3B;/B(=9B>8!+"""3$4.,*,+=0%G:>&.1B;&$,B<#73F(0.0*!*+?@8G2,8+F0
@r3974
CGGTCATCAATGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATGACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACNCCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGNCTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACACAT
+
(G?=B@FG0D4</,@)H*"&1A3!*-21G24%<)=981,+GB30#!D/#>45.F)F"$+?,&)1+)D9$5?8>A7")6>&*-H7B/-@&F5=7;H4>235@(6621C14F9:-"5=%GF2823A7>7G$8=85#>49C2!%'&4F?+27$/1?/'<)DD*1+B1B*$9??$'61?'<H)C82D&8*$<;86F&@.0-6*(=(0.31E6:H0"5*911CD"!.;,*+,B-4!;"F!E#*,0*9.1*82%"G2*94>.;9*H902A!.:!
@r3975
AGCATCCCTTTCGGCATACCATTTTATGACGGAGGCAGAGTCATAAAGCACCACATTACCCTTGCCACCGCCTNGCAGAACGGGNATTCCCTGTTCCTGCCAGTT
+
++-F01G7A'"H+744<8632>77+62F+,EE4DC:+8)74'@43(!>>4"$@//@+.G?>-<@%!<F2/"!5+/>@?C*C8:)09$&+DB'<3E(+7-!;80(4
@r3976
ATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAA
+
3&6$+:H:#'CE-2((*8='8E-;:'G)(A://5%(D+8-;667-=C,/#-!H(.9!F);4G#>D9(C6H<$!H!
@r3977
CTGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGNGTGTC
+
&+)!+""&$%%(+)$&#"&&&&!&'$)&&$$$#**)'%&+'(*+)$!*#%
@r3978
CAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGAC
+
/<?C/)5:'/'8=9-*:)7<A5"9$6F!'#4''@$G:=33C1-5>A6:
@r3979
NCAGAGGTATAAAACGAATGAGTACTGCANTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATT
+
$GA"B9(.%*0AGC;>013D*2!%DA8E>$;"/!'(7:8:#B;,98@%%2<!#/*.(-?<;%5?5B3D/.06B!0
@r3980
AGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAA
+
5*C@)-ADD+/#-2@E$DGE2E%B/7D:<C!>4.@B5/513;+F7;""AE2(&%$*&:"0-=D/?C<(*10(H:,7:5.6(!--C#0):;>*;
@r3981
TTTTCGATCGCTTGTTTCAGTTGCNTNTAGTGCATTTGATCCTTCTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGT
+
=2.2FA:-G%7>B&3.?4.)-!;A4?:**4(2&#!%G5(;?9.4H;/(A!?%%%;?=.-C,@F.,/=;G7:8#0#&%8@':90'>1$;E4C!A8A(?DB$&,+%?)15A5(<DEC)4'/8<6;:>"97@34,%%-HE6#E<06G8<6@BE5')&7$1,A=#6D%505D:(;6#D-C;,F7$'A-0?6.,
@r3982
GAACGGAAGCNGGCGANCNCTGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATNCTAAAGCTGAAAATGATGC
+
'%#&')*($%(")&!""!$%"+*(*")$'%)#&!"&+*$*!"$'+%(!!)'!&#$($#%%+''$%+#!"(%#%%"!%*'"))*$$%%$++&*)"!'%!*#+$%"'!#""&$+(+&%
@r3983
GCGNGAAAGNANNATNNGCGCATTACCCAGCTTGATTACGGGCAAAT
+
*&%"'%)*)$%"#'"("+)"#+*$#%)!(+')("*#!#%"("$!!#+
@r3984
GCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATG
+
/-E00'9G;"1)A:80723+?$)/%412!$F<F;2"D%20(#&D/%/AH#9-+054$12'GE6=7;E131G"'F(9,043=H%(;>*D#-274)G<B?"?5<<A/A%)C@A?,-%A&.%;95(43.AA$1E@>F->"32(;.0!AB/%#84+1!6G32+87,&>(8+5(4+68,)?9G4B;F@B'"?$=E>"&=H")#/(F2/A5:+F-;9:(/+0?G&5%>7.26C#)38.%=5G,1;.F.:%;*G0G&7A9)5@4G)0'
@r3985
GGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATANTGAGTGGCCTGCTGTCCCTGTNATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGG
+
!(?5%AB.4C6AA./$)=>."'+?&C*DE!DA;16)(+@&<&F*)52E(80BG)+5+*3=13<GF,:2HBC:@?.#+9A9F&)).D0=#H5",5-<=,;)/.FH"1.'52+?4C%#@5&A>9+G
@r3986
AAGAAGATTTNCAATAATCANAACAAGTCGGCTCCTGTTTAGTTACGAGCGACA
+
*#)$)'**$*"&(+$+)*%+('")&#%!%$++#!$)%'&#"'%+*+'(&%!#"$
@r3987
TCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCGCCTGCCCCCCCTGTTGCAGCAGGATCAGCCA
+
2$#;':;126!H4>&:7F)B"3$=0;F4@>/C?,B7&E':B%D5!."<-,/.C!CE89B:9HHC2C>;-DAB5/(?+:+A"%)+1
@r3988
GGGATATTTTCGATCGCTTGTTTCAGTNTCGTTTAGTGCATTCGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCA
+
;9C2<+)C>7<(2H35!:H2C)@.25@,+5E8@%A454#8DG6(9$99>.1B)C:!?!5)<AE%4&=4G*>7-$3D-G@
@r3989
ATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACC
+
>-D6CCG,D*'*,F<!5#866"7%=(-$9&:#?+C>;/1EF@8/,(73'+7&0%!D6.E1@8/.4.04A(-C0/0765E5B&(58B8=2G$68H5B27$1H)>&5,<3*-EA1!856=!,@0/AH7*-!$2)8/>#0B+#?6;5&;.'A""#?4(G!/6@*5%8.A$A932+2=1B?F.*E1E9,6.A4-G<%)7#(15A9FG'6DC6/G3%;/8=&7HE;-+D0.38#(E4:
@r3990
GGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCGATTCNGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGG
+
D-552@.$:&-<,A>##+G?5;=:,-#F56>(4.H.6>'#G#5C)-A89-"247;2*D$B$#%71,FB34<(A!?C3E?0+H/3**40@31?;?,"7.+"B?22B'<49"$#+1$?%(:4;C#=5%2D)%+?6#)18E(F$-0!(?30'$!9;FB>&33!B#=)G!5B%;>5&
@r3991
GCTGNNNTNTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGAT
+
$'###!!*"(&%%+$((&%%$&&$)""*+'#&#!%%(%+#!#%!'!))($)*)%&!"*%$!)""#*((#'
@r3992
TTTTCAGCTCATAGAGATGGTCTTGGGGCGACATNGTCATCATATGCAGGAACCNTGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCG
+
D5(9HH>@G095B+$8G3&&.1+(A4*<7E15?<!'4.<D5'$?C7F"#/A%H*6-'<F/"#70&D954?"/C%5C/.@,@>1=/!@HB'3223&2,=)-?E72@&;.E5;8E.2!7.?-:6#&0#5'C@2.C.?&3,,G/?<*#<H43)@
@r3993
AGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTAAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTGGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCT
+
=A+F7/3/$/:"2B)B")-4-1*95.:@!;G6.H<-$@!D1.E+)=15!(+%49;9A9?7D-19>1C4E:!C?7#'G+7'7<2$C6.)+4?*#4E=)1*2<F#,#8:BA59A%=$$1HH,C@:&CH7#)'95$DH0;.7!$;B;E:<H.G+';34429%3&$<46.+$*,>+:<-?F3"-C#D>(#$@28=$F8,?
@r3994
ACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATNGAGAACNAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGANCTCCAGCCAGGAACTATTGAGTACGAACGCNNTCNACTTACGCGTGCGCAGGCCGACGNANAGGAACTGAAGAATGCCAGNGACTCCGCTGAAGTGGTGGAAA
+
@);+-CG(6!1#?$0-FG,3H*+!?@3HD;:D?5(":/3/$)AEH+;.;F$=)<3?0G*BA,E:/"B$8!"4<91&5A&G4B!5>@0$HAH#?)38B2-F@>)9F&.!2<(-1@!*GHD1>3$D(4=-!H4AHF)#D6H*C5-3<F.>-3806@<5'4=52E%<B#=GAG%F=0?3*$,/8+(DHD$H/370=-'/'.2=C6%B;D>':6E.FDD@0%"D8)B$<-9)4/<0-FA%""','(3@3HD+>+#7:545EH#A
@r3995
CGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAANTGACAAAACCGCCCGCAGGCGGTTTCACATAAAACA
+
B$@G1;HBB:!@6D76"=<,<@3:*!--$4:/548E5((H1-0EF;")AB'8GC?"14H3,(B0+G/+9=6?:EE*5:;;H#!=73
@r3996
CCNCCTNATCCNCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCNCGATTCTTAGNGCCTCGTTGCGTTTGTTTGCACGAACCATATGTANGTATTTCCTTAGATACCAATTGATTGAATGTATGCAAATAAATGCATACCCCATAGGTGTG
+
'##$('&*''#"+(%+!)(+'%($"#%!)*(#!''(%)'%'$#')+#&$)%'+)))""*#)!#$($)&"$+"!()$(#(%*&!(+"$#)'!+"%'+(!+$##()%#+$(**"%$*)!()!*%!$)&(''*")&"*$(#'""#**#&)#('&*%%#'%&)")*"#+(&#$%%*"'##)%#('"")%#!(!$("#
@r3997
TAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGANTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTAAACAGTCGCTGAGCCGACAGGCGCTGGNTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATNCGTAT
+
@3"4>(+C1"B)35=*(8(HFD.?F=54G?*<@@58HB"H#D6+>/4"/:>;+H(D62@3')4-$141#F1G>02%-(.@2/4$"B$($("<)-C9D8>DF=!!F%;E<?:3B'/#0%@=CH>;!+D76/!/D/H,#9:9/?CC3;$(0D4./*$6$;*;D=;%%2%4G+(9F9!3G%1-4!:-HB-'H(9+-"C=2(*
@r3998
GCCGGACGCNACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTT
+
02G8%8#:?E!D?CB8);#$A=D/*75:1*B7'2/'B6#%82'7.@2F8@'.E(
@r3999
GTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGNCCGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGNGCAGATGGTTGGAATGACTATTNCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCG
+
E$(+G*CHB:E,&@??'=;8%5+?E)@&&<;/.57=="F$D8C!%&HBD"".#)$'&"*4?3;+)'"EF1$G=B7/34&73F>GC8C17/4>#("85@<7)D44C<F)<&DA'H0G+'G/:'0G3!4A-"#;("&-.;H;&.4#33)**+B'HA8G3$D!("5?>F="7DC,30>B!9F>EDCH5$7(#?(>"#>;HE
@r4000
TGGGCGTACTTTATGGGGCGGCGAAAATTCGTCNCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGC
+
7-/.&=9&-H4.@")2?)/(.2<'6@H=."@9*D.&&?!5#@<)B9E?CGA9%*",6#@1(+-E"4-1$F,8$$-/F?;-.*4)C*3#F=
@r4001
NAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCA
+
'FB(9$=28D</&&9*",<7DBA58F:/5:$<=><%::CE9./F:=7:)EA0%!36+><$!H/2H'*A+6<4>:$-57$?;%
@r4002
GAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGA
+
&+$))$(%&("&#+(!++)($+#+*%+)+)#%!+%#"+#)($+')#(!"%"$%*!*)'$
@r4003
TTGCTCAAGAGTGATGTTAATTTGTGCAATCATTTGGTTAGG
+
?(*&>#$?)#@1-"7+;8:7&1B)C2+D0:7=.E>7-.C#1:
@r4004
ACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTC
+
+-%1D5#;"*G5EG&&%<3D).'G:81D*'CG@#8?,GG92.G)340
@r4005
ANTANATTGNCAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCAT
+
&!&'#($(+#")#%&%(!)*&$#*)&$#"(+&#!((*)&%')#&(**&$!)+$
@r4006
AACGTGACGGACGTAACCACCNCGACATGTGAGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCCACTCGAGGTACAACNGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGANCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTAATGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGNTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGNTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCACCACC
+
,<;5!!E$6+%2C,F6;2"'0#7+=!:=-)$A))#(0>,H#&3*&@?&<B07:;'H/G/?&E)&5H"-D38;2G6="E+%832C!$+23@3=(4&<EGAF:=<?=H'8F(A'';F?E)67;=D4.@+3BF$.E%G547'#"/?-488>'E9A/=@84G&B+;#2%1%#%=$5E'?*3>;5.4B,E:;%@13G,HD%(*8;/A,C*>A,BC-.>@6!";HA,B<::9???A,*1$!,;)3FB9?D4?%<0B25$=98:?@3@0:3/(EBH'C(/32>%B76.@/G@87E71H,E>),),;*>&)*=2@>7<E3C3DCB$1+"=.0.+7%$8<98";&?"!"2<G3@20-D=3"#<(+2(8,$..426D?E(559"!*CA27$(B'$*(=B*'1/H!:36"9.)22..G'3?*E2DG+01GF);-8E(=%53('!;=*8A+4FF1-!08&!F-0<<<C0:8/<89E'5(2@*,8?)3>/3;4<)D?BH1;@EC.-1"E''2EG+=B*1/4?&H2,(:@'F0E
@r4007
ANGCTGTTTTTGCNTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGAGGACCT
+
'#88GF>>#+,F?0%537'4.;4&;=6+>E4H@=9(;40(0H3G8D;';2$7*5!&D>G@A
@r4008
CGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAAC
+
.C@D$5+C"#6A+E/0EE@F@DE&(6$4,HA6%.HE2%=>2+%>H.)/**&B*6&AF??#E22F(
@r4009
AAAGACATCACCATTAAGGGCAAAACCACCTCGCAGNATCT
+
9$2*G'HB9GGB(#BE>:&072!,&+'?9(@)*F,40-*@<
@r4010
GNGGAACCAGCATAAATCAGGCCGCGGCTNAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCA
+
&!!$/++"A20:#(,E.-#$;24!>DC&;?2D+>94=8=B<2H/7!@=+/!"$8+F"F/?@&-;G/$D2'CHE8A&<$?8==?)C=DA(>=>D*+F.C&G#!%'.8(>.4$B-=$%83%<,<:H4?/4=
@r4011
CATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGATGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGNGAACGAAAAGCTGCGCC
+
*1.9BC>.:)0C7))$G?@H3E!@@>=<B3&9%E',)G'=-?,8B%$0>(%7-AA(%8$"'!!H<A;A2)&47@A;903<+D?,%%C?1((B26=4<%8D)GF711$"H;$?7(E7$-02@(8("1#H(.3(?28(,E'8A!;$)C'=A0(.!G#!A/++5
@r4012
AGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTT
+
?0$1H*E@!@&<)6?&H8+%4014($9H9:6</D$/?#)+G$!FB"=7?C;-#"6DFE:"8>?(F0!DC$/44+C$-6+(,%
@r4013
TGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTANGGATTAATTATCAGGAGTAATTGTACGGAACAGAATCATGCCTGGTGTTTACATAGT
+
E?<.@*=G4;3%?4HE"?2'>B'66'8$7""<$2E#4#-:$3H"?#*$$6#E&,;+D.>2F:'2/*=0?-1!!D$:&!A0+)D928)>&:1?)9<=%9:%B2B,9CD.&D:00A'>&F6@H=F4'AB1:9>H$.G9!8C*98&AC%!3BD0F0A2$'<;=C$%
@r4014
NGACACCGGCNGCACGGCGATGCCGTTCATGANCTGATAACTGCGGGCCTGTCGTTGTCCGTCATCATCACCAGATAATGCCAG
+
2)E1DC>0<3*(?'3:8?"G:2C6G'9=A%;8G"1C=<3C5?>-?B6'%,C3C9C(D&(2C5!32+A(6F@*<;*(7!'";C<:
@r4015
CAGNTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGG
+
,4"<<!3D:(-#.+,"H"#B@?%"5=BFGG158;':=<$.1<.*+@(CC;%F0GE:!;3F$+)17;+$69;H@-623B2
@r4016
NTCAATGTAATACAAGNTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGNAAATTAGTTACACAGGAAATTTTTAATATTAGTATTATCATTCTTTATGTATTAAAATTAGAGTTGTGGCT
+
!0.A0FB?A.-05)2:=2;!(1&=+F*68=3:':F/G?@=0!'7%?)&-!'8%3:%2%8?*72-7@5<)$=@3<>$3.29A(="H-7!DG?8-%'5$(D4B(<8'F8GC%8A?G>%@)C:B$%9>3E18
@r4017
GCCCCTGCTCNCCGGGCATCCACGCCAGCGTGAAGCTGATATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGANAGCTGTCGTCATAGGACTCAG
+
D*H=)=#4@/-6-E2@-8$:D''6>?<$#F<CG'/=:5)29-0>DF;60@<1%"6!:1"D#FC4E@0,)76G0'&$B(+:&!$#2H2(#.F(-D"5A,+5)B+@&D*<="72*5(>0/$3FBG
@r4018
GCCGNNCTNAATACGCTGAATGAANTGGCCGCAGCGCTCGGGAATGNTCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGA
+
$"(!#((*"#))')&)())(*&*%))'+)"'*&'*'#!'"%((!''&#)!*%*'!)&&*%$+'**!!%)+%##%!)'*'($("")"&)+%"'$+*+&!%#&%+%'%!&&#&*"'*$+)"'$*"'*&&%%'*%)*%(#&"!)#("%&!!%&+(*'$*#!&"&&("(!'#$"
@r4019
CAGGAGAATGGNATGNAGAGCCATTCAACAGAGTTATCGAAGCNGANAACATCAACGACTGCTACGACCACTGGATGATATG
+
;)+.'-G-+3=:(9H?B>)G)>??=H27'D&#@<:+.88<6C316HG34H7$($><>('/3E#9+2C>!0$"4&--(:9*:!
@r4020
GCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTG
+
."-5!1AD>B<)2'-;*A7;=<,@>CEG,8A1'-5B""-G1E'48'&@>(;7*DE!?
@r4021
CCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAG
+
6'*,7&4!<B!E2G!:,1A-8(.;3(63)6<)F-4,<)D;6A8-BB'-#HA;@;).'B;;)D)(??:-*4F!53#;9.9@><5;>F"&@'D4/6%
@r4022
GTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTNTTCGTGCGCGC
+
;A320!<%.8;C/02!B@E<D81;#&39HDA.&!(#C.<-;%73655%"0,'@:(&/<-#,E:$H$H1/2/(9/4<9)7(
@r4023
AACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTT
+
=:<,4B5:270(E$(4<>4=8<.H0./!&+?H%):/<2="';%#0=<@EFGDEDA!*+>-3-+;AC5.
@r4024
AGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGT
+
,28BGBGC@*%C"48!C3$;6<7*1#*F(.CD%:$(0'F2?!B114%8>#0E5"5#9)C30
@r4025
NCTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCCGAGCGNTTTGTTCTGCAGCTGGTCTGTGGTGCTG
+
"&31%A@2G7?BB'?@EC>&%%'/H$>8/86B51-(84)5-5#-':-A*$;50$?="9&(%C!"+)'6@D:)1881@'.-E$85'GF"9'/3A2?8?3@7390'1-#*5E6#/?2BH45
@r4026
GANNATAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGNACAGTA
+
*$%#&%()')+*'%*'%##(&%))!+'(!!&**)&'+)*"%&*)%"&%%))$!*!&$'+&()##"!)+$''+"$+$%$%)!+!#&$*+!+$#()#&*&&&*&+
@r4027
ATNNCGCTNCTNNAGNTGACGATGCAGCCTGTCNGGCGGACGTGC
+
##"#'('$#&(!*$'"+%($$#$!')$#+('+&!)+('!"+!#&(
@r4028
CCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCAGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTA
+
9&6*F"H,+';>7;/.&!,!>&1+$H/D3<-4F#0E:<!F5<94GFF697$5E//,G1*F/&1"&B'4H/)&33+AAEA6"-$6?6:H.2)$73H%(H46EFH)%E$D.0&*>!80:8,49"-7A4""
@r4029
GTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGC
+
,<.>3;(,!%+(;@0#";(G/&%<4?52<1-/3.$=BB2?
@r4030
GGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACAC
+
-/7F=E';(<%E),"/4D.2)2%;997&33"2/E!/!3E/29.3
@r4031
ACGCAACCCGCCAGATGTTTGNGCAGAAGGTGTCGGCATATACC
+
#;)$>1AE)++:,A?:%D32H.'6)+G.;()D2<&6,:2='HF?
@r4032
TTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTC
+
+9;+!07&*-1H;$HE$"!)!,@(=EH09+B<@#9)!D0':G4B*(
@r4033
GACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGC
+
;A6;(C&(643'%.*C@$/"828B!>F0.7B"F6*7+%A!0.(/?C2/E1A<?4,AAG76&4-8
@r4034
CTTTATGCGCCAGCAGGGATNTCTCCTCTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGT
+
&:&8'H8&@53$C?(1E?0/(-+8*.#@)%*FA1A=&68!"2.6>3:%E<98,@C<H3G1?.:ED
@r4035
NNCNTCTTTNNTTCCGNANTNNNGNGTNNNTNANNCACAANCGCNTCNATCNTANAGNCATCANNNTTCTNNNNANCCNNGANNAATNNNNNNANCNNCANNANNGTATNANGNNNCT
+
$!$"#"$"$$##!#$"!"##!!!!"$!"""##"!$$"$$$$#"#!$!!!#"##"$$$#"""$!!$#$$#$$!"!"!!""$###!$!$$#$"!##$##"#!!#$""$###"$!#"!#!#
@r4036
AGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGA
+
07?4;0*;+E.!68G&$:.GHD710<!%:)$F&)"/B4G+4-&5'#<!
@r4037
TCAGTACGCTAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGNCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGNTATGCCGCATTGCACTTTCGTCCCTG
+
5:H-'@'>:@<4"/C2&8D9FF#@%C#C&&9<'*?9-FF3F+9@>.39%<!01E!.<AC=H+D.35#:-#2H-4<@).*A89*E-+?<'"0?84G!=:-:=/!@<)(A$F176=G%=+,4?0"B1@
@r4038
GGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGACGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGC
+
1>*D;-DE+?E"FA2=;35HH&59'*>..5#?CD9)'D1G$-"AG(D6$%&)8(#%BBB804#."+,5$GHC;*,?+$6:&<E'$&=5/17%:1(!4:90-?F3!9=H>7G346=%>9
@r4039
AANNTNGNCANTAAGAGNNNTANTCCGCNGGNGNGNANNCANGNCNNTGCAGANCNNNTGNNGANNNNTGCGCTTACTNNCCNGCNNCNGGGNTNCCCNTNNGCCGNCNNNAN
+
"!"""$$$!"$$"#!#$##"$$!#$$$"$$#!##"#!!#$$!"#$!#!!$$!#!"!$"""!$!$!!"!!""#!$$!$"!##$$$"!"#"$#$!#$$"!##"$!""#$!!!$$#
@r4040
AACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCG
+
H&HG<2;:)2&GHF&-E$(.:'3E;:CG'%0!9/4,::<=+D<GE(3>"9;.&
@r4041
TCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCNGGCGCTCCTGATACGTAACCTTGTCTCCAAGTGCAGCCAGCTGGCG
+
="-BB/-6:(9G?G"$$G4CD7)4CH?(:/E*;"9#(#4C)5H$1)F-*;/&A@.%':%+B:715:>0,+/<0>3*5#F=#%H&7.C9;/8"2B8G8CB<&-3"G;#/+1:A?
@r4042
GATGGCGGTTATGGTTNGATTCGATTTCGTCTACTGCTTCCTNCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAG
+
(,H;B8H%0:&GD569*&>'):C0!6++!)G.A'G"%<<=@!(3E"0%(42.G&*)!->)@4BA?4F++:6G<%6G)A$4/&
@r4043
ACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGT
+
C:;EH$!.:#5C4.D)1@"=(:E)*7H+835+H.>F"37@-5+:'46)$2%*1%:!91*>:+B4)(3"!!'2;9>'<1@:(>%>E=:/4/D.>9#0"*E<3/F!2#+56#);&#%501="!=/-'>D=C,.,;.DF+(;-C#;1"H?$
@r4044
AAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATT
+
A1+*8)%<;,"/6<B;D&!@8'F,7>8?/3>>,+;'C*);<20D'#=?>B):B6*<"+A.*?3#9HE.5G4F@@E86'((+>DG,4*=36!C4?4*H2E$5@'@+9%5H,E+5#G#2<-)-E;/.A2DF;"D$.)<+DB4G3'2H2;A,$3::3=E?D<#84
@r4045
ACTGCGGGGCTGTCGTGGTCCGTCATCATCACCGGATAATGGCAGCGTCGCGAGTGCCTCCTG
+
+*'%$&+)"$#"'%()"&"*"*#&*%))+'!$$(!%!&('!#&*%'$'(%**&'#)"+$"!('
@r4046
TGNCTGTGGCNAAACCGGATGCTGCAATTCAGAGCNGCAGCAAGTGGGGGACAGCA
+
)"!&#*(%("'**%++)'+(+!+*%!!%'$')$($#'&((!%'()'&'$#+$#''(
@r4047
GCNTGTANGNTTNGNNCTGNAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGTATTTCNAAGGTTAGTTTTTTCATGANTTCCCTCTCCCTAAAAAGGCCTG
+
***((&!&'$))#'""*)+*!+"!++*$%#&"&%#")+'%#()(%(+("''*%&((&%)$!%()+)+(*+"%*'')(!%#'!+!#!%#'&'$&*+&#*%%&&&#()*)%'%+$$%&&('!(
@r4048
ANAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGNGCGCCATTGGGAAGGNGATGTATGCCGCCACCATTGA
+
$!=B=7?8'EH?0:;G<=);,+:+,+-4*=40<6.E$505G+6E?"*$@<5H9<'=*/'90+233+;57'.*>,2+9/:<1"E=&<0)*'&HE5
@r4049
GCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCNAAC
+
<"1E-DE-5%D.F80;)=*,.,+78)-G6;-'<!6C9A<,'#-2
@r4050
ATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCANCACCACCGTGGTGCTGTTACGT
+
42$H@("1F8E99)E9<DD<D:A/%F15;F*0<9:FFH/20!+53D$5@B%-:7:G$EEA)@B+2H.2$;7&/D-5
@r4051
CTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATCACTCAATGTTGGCCTGTATAGCTTCAGTGATAGCGATTCGCCTGTCTCTGCCTAATCCA
+
:H+C9G*7>0+&7+.%AG45,A-:2("6,$&@:&GB*H7("AF.D*DD:=7EC;;B19C@''4#*002$=>D+<D%2/%-2-B;-$G+00D%>)61(9-2&G''+"1&$>"&)52D8#G$"&7F0/"!4&*;!>!<6H0./<('2H(B<$F4H&')AB-;=7
@r4052
ATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCNGCCTGGGTCCTTGAAGCCTGCCGTCGGAG
+
<8>(/3)&F/2@!7>"G?G,7,=>H=CF79:0E(F4G7C8D-00,51%#@E.!C:8FA4D*.03=#6=G67/?65F#A;F
@r4053
GTCGCGGTCTNTTTCTCTGATGAAGGCGTTTACGNCTTGTTGNGCTTGTTTAA
+
;!HB"20H?%-+9'),!30A$#387+9"0&<@)A3C2->:&F+3!:&.6'40*
@r4054
AACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGA
+
<+5+<;>+?AH361F2!C7C45<F.<?:6DH!&A,74F6D$'6;>5="E+593(26+.3.,8"B%0?+7A%
@r4055
TNTTCTATCTTNCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATA
+
,((:$!G&F:(%0#4,(-3?3:=)'6+??6<H%(/3!E!A%'("5BD8E,60"<H(:&D@*30,>.-3!=>)@60'-A&++<F22"66)83#E=2(D1#)*9>EC-2G5&+D
@r4056
ATGGCATACGTGCCGTCGTCGTTCTCACGGATACTNACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGNTCTGCGTTTCCAGCAGTTCTCAGCCACA
+
,$>H.B>4D3F;*A@)-E"9.4;C?FFG)D?6,<?@;525.9CF+!4>#9HE)3(F+@<-F#?,>91F93%.9AA>D2:.3@@'FE:4FE,A&?7702*2+,)=?2?#/@&?2)<C((!%"B0F.D')HAC-.AD#9=%0=2C5,*@5=!)9#!"9F'D?2:A5B+<3=8$/H-0B-(GE+-#(#CB=9&"?<6!<+/-85<*G+"HB4<&"1HA<?-?7&)$8:572#29!0A*AH"E?0&B2B-C0:$)@30/5EE28E89"G==#*#@5+A!D7&!D5):A&"'5502H&D<)"(33*24)(0-G<C$2':9!*98)7-E,B1F+"2?ECGG'5B19(->48A)7-#42;(H%,=;9(FA./4<=-E%;H&E9'2#:(-1F03.,%?A9@/3GF"F7&H%0
@r4057
TTCTCNGGCTGACGTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCG
+
'*$"&)+($%%&$%"'(#)(#)(%((&)%%#&#$*+#"!!#"+%%!!'$'%!$(")()*&+'%(!$""#+'#++"*+('
@r4058
NCNCCNTTNATGNANGNTTNGGCANGGACNTNCNNNCTAGGNATTNNTANTCNGANGACNTNTGTNCNAGNNGCNNACNANNCGGNCAATNTNANNNACGNTNAANGCAAACCAGNNTNANNNNANTANCNATGNGTNCNTGTTNNANNTATNTTNNTATACNCNTNGCNANCA
+
#$#!!!$"!""$!"!$"!#!$#""##!$!$"#$!!$#!$$"$#$#$#$"!#"!""!$$!!$#"##$$""!!!##!""$"!!"$#"#$"$"!""#""$!!!"$"$$"$"##!$$""!#""""#$"$$!$!!!#$#!"""!#$""$!!$###$$!$"#!##$!"!$!#!$!!!!""
@r4059
GNCTTGGGTCCCTGTAGCAGTAATATGCGTTGTTTCTTATATAAAGGTTAGGGGGTAAATGCCGGCCCTCATGACTTCGCCTTCTTCCCATTTATGATCCTCTTCAAAAGGCCACCTGTTA
+
%"$+(%"$%%'"+($*##*+"!"#*(&)')%+(*$#++)(!#$!+"&%$)!$(&"#('&##%+'""')%&!"%))!%+++('+#!()###$&$)(!)$!+$!))$%$*%&(!%"#$*+*&#
@r4060
TGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCANCCGTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGNTCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACTCAACCAAACATGCAATGGTAGTAACCATTCGGGAACGCAACCGC
+
<9)=,")5'6?BA$G+?%2$;?723$9%@4G/77E)0&9"2@$5F1-?:4<H.708"730/'&C7#'5'#;7D5;E83AF9#6#6F"%A#D!>?*-">7$'+='0D@@-9>";+3=)=C)*<=2;H12>G?$.E8"'D-C6>"2.81$/!.@5E<6&)B57+"-'67*">*(/F2$3+/B=8AA673">B&-+)63D?>&!&"1
@r4061
CATNCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAATACTNCGCCGGTNTCGNTATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTGGTNAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCT
+
6:<H#29E+,&E@'FD"""&&?!F#@;'6#@3)3'+,F(+&8=1)1%<G<2#3E#EDF;7#;*DE:*9!@*2)"7F2/!.@E*@FD':6A$&<F/A*9D!8.0H;4$BG0GG<(;561*451!HB@0;<.$%!13.0B!'#F#05F$?A;DFHE7%$%F8H@F<;:6<)"7;1*815>2H):C5!C:>/@(,:&B9894
@r4062
NCTGTTATCCGAAATCCACTGAAAGCACAGCGNCTNGCTGAGGNGATAAATAATAAACGAGGGGCTGTAT
+
$$(#+$(+"$$)%$#(*(#)(*$)++"#$#'+"*!#')#"*"&%('#((#'(!"&!#'%"#!!%#(&(*+
@r4063
TCTCTCTTTTAAGTTACTCTCTATTACATACGTNTTCCATCTAAAAATTAGTAGTATTGAACTTATCGGGGCATCGTATTGT
+
,/-@8.(6%H>,$*,.08>C<2%<4;=+!=+#28=45)$"1(4F8'$!+C6)@*6.("0H2(@#%'(7$)0(/G*7(22$=0
@r4064
TCGGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGNTATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTAATGGTCAGT
+
(("$>D0!:?,!61<F@-B=G3#290B%*,5=1E);6D=:/8*$):F;E)<)!3?#<-&+AB138F)7@D/C6&;=8'A/0CH<A*G%=H6&&2(9B3-8251?>$F.-7+CD56C04B.(4:2:?&(%$$G*<D86"$DE6;;4
@r4065
CACTATCGCCATCGGCGTTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAA
+
HD/>>8HB?3BF9H9FE-%9$0C88450+",&>+$5FEB3#8>!$G!45$08/&2<F0,3)0E@B78!@BF$G:1)%3>C&9(>9F<(B5A%G9+!:190C9.DB8-97%4-,E#&.D?(@1734="3B(1)0>2842#>1(#6F"'1D-E@),6.69<%(87,".,)''..F9(9=%)4*#9+H54-G'>5>A'@,81.8039-3D'5!/6,@C""*GG$"",0/1A*BH*(;&@
@r4066
ACAAACACGNCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAA
+
'?)C3C4"9!C8#("?:5+6%"*2/0,=*2H-,7BAAF79*)"@D<)#*
@r4067
ACAGACCCGACGTCGGGGCTNACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCA
+
D<(8C>"=91D,*D%42+819')+@'&23'/H*+46E#$-#897/.=&1C2>FFF%7A*;!1<E25G9/;%D=:058B6&";=F0F-:4:*0%@+";21!54!6?F@9,=F(G8<(
@r4068
GGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACNCGCCATGTACTTTTCANCCCGCTC
+
2B-<F;!=#C$/'6;D5@=.ED6:;G-C!:!6?GB@&*69BE#7#04E-4#:"774"@3$B.HC'3B7E:4:?86,5(CD4%+8*E#1@<E.=E443-<4=<DG.GC&1B"B)G9758/C",+7-17#8=0?;:#-6-?H$'H+F/9&G/)?GA2F5&('4FB<./92F2<A,0*!.G10CH$E5##!&.+
@r4069
TTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAG
+
B85,9.$0G7C:E0!23E"9F?/?3>+3?A*65)G89CE!+
@r4070
AATCCAGGTATCCTTNCTCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATNGCCCGGTTTGA
+
:#:5A<&D@2E<G%(D@>6*8A1E19<557D'A!7)G:G.*(57,>.=7.(55.:!%:$:2-E).:=),-)H(!7C8<+3!.885?*C-:"%G2/$EE41?%96@94@6AH$E#
@r4071
TGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATNGAAACGCCTTATCGACATACTTAATCAGCCA
+
)@E<*'$.FB(";(43A2%73,=&3.1BE77:9)7/<B>!70A2-1%(>51%HG%>8:%63CE=2;>6*-%9="'D5+0$)9(B6FG-5"#)'4.60;.G:%(-C/
@r4072
CGTCCACGGNTTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAANTGCGCATCGCTGGCATCACCTN
+
C<?'$8.G"2<)2*'$6:"7D*F57/#*93B%5:,*,B,2D2("9E'"6/>;B+$BA9>D%#07*39%?=0>3*
@r4073
CGGATTCACTTCATGCTTCGGCTTGACATATCCCGGNGTAAATT
+
,)%(8?$?3!-(E',@5E3&A?(B,=G,E+C444=0!7G%.E;0
@r4074
GGCCATTGCCCNTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGANGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCG
+
H'DE.?(!@>6."?<>92,8D13!<?=+3,#7!D,*D75.';&-<6.:(.%)4%AF4F$9'/34;#A085F925H!(GGE%4D1;&-A8F?FD=.H.AH:2.@39E4A&C-(E*168G>4(.G!'F'245,/G",6+FC"";./,5"HAFD5+4D)!E9E"D<&'B4.*@B%0/AAC>/B!58H!AA;:9'<F/41'H56#,:0A8B)!)*4#')#0)),,-(=#/;CA<70=<C=C=AC?@?&FB+!F%1>
@r4075
AGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGT
+
(.$CB",F3@+$@!<)4%:?*0=,%D/8EC(4$6C*.6:'%)A'15137'15:%$/'+$B!
@r4076
TCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCNGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTNCAGACATGC
+
?;<-0.++8?"!6>)$8&C58,D>F184D''/@0934!,;F7*=(G>6:%.A?F-G=#C=AC4$D==/*+>+9'G-D#78F21/-/A<?!+A
@r4077
TGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATT
+
E+'('8F#E(20<!H+(91H*:,HA060>>$%/>*C@4(;$+.D1B$%
@r4078
NGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGCAACTGATCACCACTCTTCGNCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCAT
+
'*(+$*"%)!&)!+(&!*+**"$%$&&*'+$*()*"&+!('++*"&'&##%&'($$$)"!)%)%("$*)*"%")&"&!*!#%(*$!)!*()%'%#+$)')&)$""+%($%")*&$)!$)))"%"++&'%)"#!""'#
@r4079
TTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCNTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCATTCTTGT
+
;B3--83?:;)>=+AD)(*.B250+=2;=*C)D.1@67)+2G*D9*@/C);!.@.A2G=,-"8*/&'EFGG1%;?9E0=E/@G,'?1"G$-FC7.@C---4:#;?6-?0,@?@H,2!)<C!HD-FH.,2."/.'0)60BD*>0:D(0?<('4+'8B@E%(%4)#H@E:8C*D7<A#G>352G8++!%ED6,35%1'3D#E5/6!AF8DB"0:.%</:.BG-G9BD0%950?BE-:&/D&96!E@!3"A:?5)D5G9&D:09>2C5>;D.F9A*#3/9G04-,'"/
@r4080
CAGNCNNNNCCNNNNANNNTATNTNCCTTACCAGNAACAGNAGN
+
!"!#$"""!#!!""""!""""##$!$"""##$"!$!$!"$!"##
@r4081
TTACGTNCNAACNGCATTGGGCAGATATTCCGCCGTGTANNTTTGCAAGCGATGTGCAGGTTATGGT
+
'%%&#()*!!$'%&&++"&('&%*!!%&$$*"""!+'#+#$'"*"))'+&#!+(()&$"'&!(*+#(
@r4082
TTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGANGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTAC
+
.)(F.-,A:G=3$7;*)C;H5CG>'/E'B%(84*8D:27''7;A38:A>D!$)84!/F?B62!!3*4G,-00B*D+@2A&27C%E3%*.%<4B<D<9"F9B.4,+>7E**"74+$7&5>5,%&48=%60>,@;,7-
@r4083
CAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGC
+
/@)$($9H/C6;?":89?3=;6;H9/.&$F0;+AH='%*D..3!H3('*0!D:B*4'81/1(H6"2!$A'F1
@r4084
ATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCG
+
7-9A<)**,,%#>=A-B2*>:&>A=3-#65?GE('D**.*"8'.7-8'F9:0E>>?2A@@23A5%
@r4085
NACTGTAGGGGTTGTAATAGTTTATCCGNTTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGATTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGNATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCNG
+
'A#:($+EGF""(=$F9%?$9)9D-/:-H,EC150$(.6EH!%D0:-!ABABAF3=#;*&?$;:2/?%B!%!*2%9D(0.;!/0?4.+/G,H"C$2&H&>0E-4-6<F0#258<%:%7@B!57&!(GD4"/=>!C>(15E,DBA86A,83%A@5'%,?2E5)='/(,8#@&#&:@!-H&$2A@"AAB!D!;.H<C6E/E:=<.#.D"@&891>-!<:"B9)&:H8B-##H;BE$&&4-%BG5="0"$"2@=-;*"'B*%=C
@r4086
AGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAANCGGCATGTTAAACGG
+
G75+:=,5091*A!-E&6=$>@E+"C/*#6>+G2)#2$(/DF.?F-2G*<A;'3:8!@C1+2/+29+/<6H=@7,"/A%%B87D7C
@r4087
ACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGAT
+
<9929G)F7D>G$+5=>:C&D;.E1?#)'"<A<.9;9.@;6619D8*&33%HHH/5.'.AHB0#-)21HFCH-?-%$;
@r4088
CCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACCATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGC
+
9+.#D(#B7)!1')2$<-<E5<7%!G3-9H+*143"..<E9$1<CB,0EG*@-7=8&.1+F?/,8-#)@;A="/?H3F+G:60G,!=&0"#7A%.;;>B/<G.D,5#753%46*3"GC%'<4D+4#%(CH?722H!A151C929.C:4B)!17'(B+DCF#8!%F7&>H19=E'20<=A!6G?@A)13(7F-F(6=E'E&7H;C9#8F=G6&$:..!F-*?<H:@4D&<+7D>(EE-FH((!,AE1%8G5CDC?'D3+82$2%433$A.)E>/3</H>%&5#G74%7"D+E,6<H2<0>E9HB@4C*3BF@&<!!)D!72!("!4!01=>@'H0<'C)B*<2*5H')B328FC8:?B2,+.3"=/":06.??'"!E"<<2'%4B/GG4>5+//"B,9?##G=</0?+,5C2G0&=?)5+=8=G.??7@;+!G>5G1A=4.)H#>8FD/7+=4#!43)+5<A/!>4C!$!8?5:B.F4A$@7";H9---.H6?9"'''.D
@r4089
GTNTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGG
+
'64"D!$>B4+9./?B5H+5&:93%7@":1(9:?.@2C6!8E946.G5(?B,A#'3?=9+&9@B*#3*0
@r4090
AATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGNATGAGGCTCTGGTGATGC
+
(3*!G,#;@<(.1F'9?4>BG1+#?%<57'(-#G2;EA*0.F@H4:;/;H9?D2%"C@CF9$+:%$5,"<1>"EG%:=>2/!,=33-<$'"%"?40.:F8G+$<DHBD$@7/&;F
@r4091
TCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGANCAGGTCCCTATCAGTCAAAATAAAATNATTA
+
F''*00>1(4CE2$A3?":;*E.++H@>>%CE*(226<05+$@#'@!G!+(87+#9'39-40-92G#%?$9E**<C>0G>0:'D,$1"1<7G=9.5.).?0&(%6DG07<F*
@r4092
NTCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAAC
+
"CFCFF-E3>7"==(@#DDE=(-2(@@E045345'+<=/.,G)
@r4093
TAAACGCCNTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCA
+
:")H6!FH$!*3"@#1!H*<DH94!,499%2$B1EFE#>2'FH-'@2.$*+31*>%B;9+-26#<A@(>$/*E4%#+A6//*DH#>5.&F?
@r4094
TCCCAGAGCACNAATCTNNAAGACGGCTACANANGGGTGCATTCATTCAGTGTTTCCTGC
+
#&"('$*#'%*$&#")&$($#($'!)%'")!%(#*+!'!#&#&#!*#)'))($!*""'*)
@r4095
TCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCG
+
C)8G!19F?C<;9;365#2E2?E$;%&=75::',$*C"7>>&'/=$HB</ED8F=D@=/,*B1G@,8'H6&FHD?A?C*>H3.E=@7$C9F$+B0'G>E(DAA2%G-*E+?,83FD+3)B?8%,3=-C6F4(.8:-1126?2"')=+59$=@EAFG0<,(.2+E?4254*88<7A%B2'EH:H!'2,DE#3+2)>C<H8B+B'G<)5#"+H:?1G-H1
@r4096
GCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTG
+
.E#&*?@0.A.-$@3$6!+@3#=F)"@3&;!7386'6(&.HE@.=.E06<1=&H-:.;H6.8H*-F6.:B*4&)(CGA7.-/%#7H?".D7D.$
@r4097
NAACTATACCTTTTGAGGTGACGGTTAATTCTNTGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTTAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCNCTGAAAATAAT
+
$*#+!#"#"&))(*!'"!$(""%%"&+"%+"+(*++)#*%")'(+'%+&(#(&*&'+#%$+'('(!#'+($+&#&+&&$&$+%)'**&)%(*)&"(!%($!(#+$')!$('&$%**)$!&'$*&&'%&$&!"&%'$&#+#%))'&%!"$$#(**$$&"
@r4098
CGAAACAGNTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACANGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCANATGCGTACAGGCGTCATCGC
+
;7D&,H!?C(75!C/07#?(8!8:!+>0/DF.?&/73)F!;6F;;2<<29=?@86%&-0.F@+(:=<;?E83;3@*8*4#&C*;D9/;54B*88*/G2*0"#$<>9>0:G';8C6*)519A(1@A2:FH3=.@0''1D0CF602HE"E6/03)=)E"C52C+%HE8#7#B7*G><&A5G'A/(=,6'<,5"EH247H
@r4099
ATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGT
+
1"=DD:.:H8.(%%,'2957A/1>",&HG(23+>/46C8(D7321HC/46E,=?$6&/(?&"(F)D4@.;1G7>2:=HD<?!B7%8*96H1B+@,.((9H%.>->/C#@E=?6!+);15!GADB'1HD8.A-;7%:4E91G!A
@r4100
TGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCCGCCGCCTGCCCGGCTCTGGACAG
+
.;>>/!#@<'6',%)@2?.8<0)G0(-2$?*<41.!:A17B(2313;@D))?3<#16F#1C%3
@r4101
TATCTGNCGGTGCAATACCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATAT
+
+*!)'+"$"**!)##$+%%"*%)'*$"%$!&%#&(#+&"+&'$"$%+*'$*!"')%&
@r4102
CTCATACAACNAATAAATGCGGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAANTATNGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGG
+
0@4,@$@D2?-6;:6=,2AH@8><1B12!?>&E6<.?@)@G:5&339C'D5-@#F.AB4ECGE9HC6&%G(#80"B<((0(@'+'-<AC!D*E=2@,A.A2%-;@3.3&CE-0AB*&86>F*ED&9#,,'(6=BC#E&$9!-@H=2
@r4103
GCTCAAGAGNGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGT
+
)-&8;4<5-??1':D:35H8H:7?%F(;7H)&8B;9A)A88(G"!*(>A>@C/'(#&?
@r4104
CCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTNCATA
+
&GC7H3(0>7:0H328&C8E#-F;34B&E-A%-(C/13%BGC556)/#D8C=:3G&A=G@-8'5!'75'&,F5F7'?2A!0-F?8"$:@:%:.;$36E89&//:4(B'2??(9:
@r4105
TGGTTGCCCAGGGCAATGTTCTGCCTGTTCTNTACGAGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGTCGAAGGGGACGTN
+
>*+''=3;3@)6E9=?BE'728?((F7#H302;71%5&4(/4>&?.E:3,:*D:227'1?A'!A!4;2><18)*'5$D.*.(2,;4)HC&?-.DD??.DC)
@r4106
TTCACTTCCCGAATAACCCGNATATTTTNGATCTGACCGAAGCNCAG
+
>@(EB/1#E6+&,7=0/#1>.':C%2E&:<<>&1H8/6@+!A9'GA-
@r4107
GTCCAGGTGCAGGTGTTGGNCAGCATGATACGTCCCGGAA
+
8=C&/4&;.48E=AA)!,9,6F3048DGEDD3<?48)F45
@r4108
AGTGTATGACGACCAGAGCGTTTTNTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGACATCCTGCGCATCCGGATATTAAACGGGCGC
+
*,$%E+(#;).1>:!5G4?7A+?7?2!#'>)-EE,DG/G+<A0#3C&F6H!!/**/&0!4)B@3.#,FG#92=59;%EG"8+C'8"-B
@r4109
TAGAGGGAAANNAACAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCC
+
&&$$#)$#*)#!&#+%%+#("+)"$"$"#'"(!&!!$+%*"!'(%#('&+*
@r4110
ACGNTGACAGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAATCCTATGACG
+
5A;6!%=2>"<6(?!'+15+*,-")B'G)&!82("AC%(#65:5(CA#7.";3%%-.%>?'1BA7$DHH+06
@r4111
AAAAGGTTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCNCCATGNAGACATCACGAAGGTTTTTATGTAGA
+
+#"!&%$'&&&$')&")#!&%((%&!"!)'$)##)*"!$(!%"%*#%$)!+!(%')&)&+!*"$&###)#+*&+"''"
@r4112
TCCTGGGCAGTCAGGCTGTCGCCGGACACNGCATCCGTCAGGCTGCTGATCCCNAGCTG
+
)DDF-/H?C+0<.6-1(6=;>H2(*+,#32)$;'/C(%1<257@#98<82@=<)8:<,2
@r4113
CTGNCNCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGC
+
(*!%'&+&'$*#($%'&(++)+&*"+"*&"!&(#%+()'+!!)%+)'%*%%
@r4114
CATCTTCTCGGGCGTAAGTCGGACACCATGGCATCACAGTATCGTNATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTNGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATA
+
?'A>&2H#%.65G,+B;.1:)$?A)B=<A#!>)G9<3"8GE4,347<1,.?576,@"4E!C:+<.5*&G7E<+4"$16-5.7+&&?3%D@3@,7@-(AA22D=AABAD!!A,EE7>$1=<##D"8"7!<@'<<E;635(?F-<?G*&6$*,2"66;48B%>.:)4?B6
@r4115
TGGANNNCNGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTT
+
&*')&!!$!(+%'+!#%*'&(&+%!**+'*&$#%"%#+#'!!'
@r4116
NTGNNCTCANTNNGGNNNNATNANTNATNATCATGGCCCGGTTTGANATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAGACGGCAAGATGCGGCGTGGCGGNNATCTGA
+
)')"$(")##'$"&'#"#$&#"&'$&*&($&%%)*+%%$&**+%$&+!)((%"!#+(')+$&!*%%'!'#+')#$%)&"#&%*+!$%%**%%(*+(#&+'#!+%!)'+))%"**"+"(#$*#&$$)%%#"+!&)("*'""+++"&')))($(!*)#""*!*+(*+*##'+%(++'%!')%')*!')"+$)"+()$
@r4117
AGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAATTNTGTCCCA
+
+1'G,'5G2BH,B>:>(D?7@)>/D*%*<:EC,1&>:D(EBF)!.1?0477
@r4118
ATANACATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGNTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGA
+
%%)(&%*)&**$'**+""(!+"&(('$$&%*$''%$#"$#$&'#++'"+)**(%)#&%#%+'#&%""#*"')&))&*
@r4119
ATGTCTGACGCTNGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGNGTCGTCTTCACAGCGATGCCNGAG
+
EH0/(#7>-&8(>C68/4:%!7A;AE*6A.7:4"@,"F5$8;F!@,-B@.>'7E.&%%;!.H5&,0!#1$F&DB)?ED'68D>6%72@E>8:.C&./:05&;?B0G
@r4120
GCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGA
+
+#!*!(#!#%&)(*#$#('(()$$!"()$**%)$+""%)("%'"')*+%"#**)'&$"!%'#"*$*!$"!!%+#+$#$+&*%!#*(!!(()%*)(*%)
@r4121
TGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTT
+
+")(#"!%!$&("+&("!!"&#$$##'*"&"%#$#+$+"&!%)#%
@r4122
NGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACNTTTTCGCCGCACCGGCACTGGTTGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGNACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGNCGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCG
+
"%776HE2$.&(%?A'-9!61!H--,)20>1G8*<'#3!B8@6))'$6;*#/76%7%59HAF@E!+F80-@2)E.&(*"/",G!;D-&9?;7>)9$>59(C4!=/8+@-(F#*FB;9$4A57./&,='H=*7E,6.7)41CG<%#5#D'8)%2,-C'10*+6<+??%'63$%?7C1E!)0#+=1"E?B)'1<)D&,$,!$9='A)(1)">@%*#B#H;GG34@>+58,ED-!,+#+C=A@C@'F=;.F$8*CA.%H=A/.;:)8(,*?'!75>3-0=3CD'-?D3);56?)42!H(C<%6G;(A$5:
@r4123
ACACTAAACTCCAACATATAGTAACCCTTAATTTTATTACAATAAGCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTNATTTACTCTCTATTACATACGTTTTCCATC
+
*;&&8;:)G;6&?E$"'$@8&#$>B>/0;A">F$00.0E!D3B6GH%E*51=+87-19(AA;0/H*2):D2A4*;8@8/G#2<4:G)B&4C''H"E&9F738)':ADE4;2+A9
@r4124
GAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTG
+
%"%%##+")*$""&!+)!*$')'$")'+)#+$'#()'*&)"$)%"+'
@r4125
TTTAATGAAGGCGATACCCGTGCCTNTAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCA
+
+;6+=0F#7?*B>5:-F?.&HH5;;!:?/$E)/9$3A+H:D7EF"D#<+@:)*#%$3%;=/1A(;8,2$)+D=&.3
@r4126
CANGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTC
+
"'!1<;?5.1#>'7(*2(F>2&4:.#G2AA=/2C:9C!!4
@r4127
ATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACGGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGNTCTTCCAGAAACGACTCC
+
E0-<?;3.7=>.!1E)'A+@(='B75C:F2#:5*>&G""(5G)6,72"53#+H,H/%$33>?>@2GH-A7)%DGGA/3/D.+FA35+3="-51<8DED7<0A@9>?FG/8G,<8A@BG">E=;!.&9!>6?8(*"GD4-F-@+#A/>3@*A29@D'>,A.6-/%3/3<&F#<A>DF%!,0D0=.21C$H2?,72;7G-4B5&8CDB18<'@8>G*"5?@+=EB%$F(%9;/;H
@r4128
GTTACTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGCGCGGC
+
G"2)"&07/'?42HGB=*F*2$!A!2;"7-+);5*@%6./2&5:C>H
@r4129
CTCCGGCCGGGCANAATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTG
+
(A,6,'F*E6DD892::*//G)$%#/,)1E95GH+/8-G7'&051!%4&4H<:DB"/H$=
@r4130
TTAACATCCGCTCCTCGCTCATAACAGACATTCANTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGGAAGAAAA
+
!$&(&+++$%+)*!$#'"+$!)#"'"()&+*'($!&'##+($''(#++!+"")"$%#%%$'#(&$$)+$&#"$$"+%!%!"(+%+$("!(
@r4131
ATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTNGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTNGTGCCGCCGCAATGGCCATTAACCGCGTTGCNTCATCCGCGANATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTA
+
+/;$46%D.5B,0G<$D.D5(,%*)A1CH"1*87,+68$($<=#;;2@%=-5G.C:/<2()1?C-<C8*%!>.D)=4/9)5#23-@8*:=7;:3D9-&%B/;-,&.C$?6HA@'9=#7C%E4"<4F2,(/.*C,(("@7:&%=271$&8,0/,%*F0,;/'4+,!$:6(A?D5:$"5+*"");5B-H79.64'54$6E4$2F<24!7D";@
@r4132
GGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTANCTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATAT
+
8G)#:.4'+@4>7116;&7B=2-A&D7H"G"C/:5;);E//>H7>FG!88<<B+;&C$'*;>'7=:86&>/G'&+2&'#/C;84!"=/*55*DG?3+&:/@G@25F@(
@r4133
CAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGT
+
.%%C89*(@:.?#*;!(BE%,B"B655C#.7;0H.2F3@E
@r4134
NGCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCAT
+
$&#39<2#.2:EF/><(5";D.9DD11B,0";'2;5>@)G?($?"6C"&@D1+):3-.+!G9'7*=298;5>AH)4$..F7/'<+7;.CFCD!'1@F5.D(G>6<7
@r4135
GNNCAGAANTTTCGTCTCGTCGCTGGNAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAAC
+
*!")#%&*%)+!%%"!%+!)+'$"%*(!&"%%&&"'%("$&%")%&+$*)#+#'*!)$"*!#%#)&%+!(*!*""!("'(!&#")!+!&**"#**%(&'$""+$#%#+''#
@r4136
GTCAGGTGGCGTATTCCANATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCC
+
F7FE;0#"*G381F<H8(=6/F*@!F#0.D1%-.$@>(9B"&@39E?(A0660)(D!2D:+!/,&2CB+>C+7++5&/E*28=@.@23@73,0$
@r4137
TTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCNGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACC
+
:/.*0'BHAA6.-D(2$3<F!-847<+/'-&<:F*7/@7G'BG#""(C-2+7=3H>(%B9?+"1<6.E3(=(?;2(7*&%4(F%B3%=#1.4<>%9"
@r4138
CGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGA
+
>&-24()$G"*"0$??F'-C$5,<%%8!'F)2$E0G*H6"<:D?6-&46G9;;#3C=*:0!/G?$'64$*$%':+
@r4139
CTGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGNTCTTCCAGAAACGACTCCAGTACGGTGGCCTCCTCACGGGG
+
*#+#&""(*#(#)*#$%+$"'!"#')*)""*&)!"*&!+&()+)#&)$*+)*)+$&$)!!%&)("(*!%*&"&*$+#*&+)+*%+'")##'%*''%!+'#))"%')*
@r4140
AGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGNTGGGCAGCGACTACATCCGTG
+
--$;3F''@8*2>AG&41@#/03)$3.DA7;AD!;H,2.EE#?<8E403"=.$=>-)<<<5;6E9','(3@G5+?*=98%3>H-5$
@r4141
AGCACTNCNGCNTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCG
+
)*&)$'%)"'#!+'''*++&!%(&)$%&((''''###)&"&'$&)!$'+
@r4142
NATCNAGNNNATNCANCNNCNNCNNGNCNTNNANGGGNNGANNNTCTNCGAANNNNACCTNNGGTNNTNNNGGANACCNNNANANNTTCTGNNNNNGNNTGGGNTNNGATCANNNANNGNGTGGNCGTNGNNNTTCANGTNGTCGGTGNNGATNAGCNNNNCTCNAAGCNCNNGNACNNNNAG
+
"#!$$#$!"##$"#""$!"$#!$!!!!#!!"##"##!!$!$$!"""##$!"$$!!!$!"!""#!#""#"!"#!$!$!"!#!#"""!!"!$!!!!#!$#!$#$"##$"#$!#$$"!"!"#$$"!#!"$"""!!""##"!$"#$$##!$$""#$""$$"!"#!"$$"#!$#$!"$#""$!!$"$"
@r4143
TCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAAC
+
+"*:&6.1B+.A2.!1F.<7FC?-FH%@C+.*>&*DB:FE?*.G6;/@0<H%AC70G:$-FB4*9B3/E994<:6D/<A*+(G:EH7"
@r4144
AACCGACACGGGCAGANTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCAGGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCC
+
7@3=A9C'@=5D*,%"8"0)"@6E9@+#7.6:E=?>96HF#+BHC%G:&#!4*D<)G==)$$+@H1*,?;!B72;(?47"G7(&EG2<-BD!:+=>1(-4,B#0
@r4145
GNTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGANAACCTCACCGGAAACAATCGG
+
!!7##9GD'6/@@8!F"<B'HC66?@5=,,B?1$8!-'7AF:-H)$5&8(H,!,:?DFAA(8)?04'0A17$0,A55)G#G=@#@,(2#C%-;2HG%
@r4146
GCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGANTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATANGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTNAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTAT
+
-04??'G&A9<,33484/A!342=GG$(2'8%,5D<E2!"49&$E!9%!%'3A087>A;;8)%7>!"*&@45<(9)G&@:A)5<@@HA45$H@HC&F0*4F)0!%7!(2=*E03-H!)>G(?;09+A5-)+0,&CE$$F$!*?-9=%C8--1?!?C024/E$-=<":G'&+D:D6%.>9F(:<(F478G0E%/&D3-A%;>1+78?-,EFG'8-,=:%B/""./*:#3.:(."@E103B2457@:8$/;D@5?)5E%)>2+9E>E-<+'EH)%-2@10<(
@r4147
GGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGG
+
CEFA7:)?F6-5H/=G1/+((!99"/-+#H84<4A</3D-D>7;A=9*1F?;F<$AG34,F@C,(E):5@H5():/4D=FC('%!-%C:F<0+.GB=2;0A#EH00;&@A<9;&4')E-/>.0F2%(#%/69-A-49?,8'H?%E,)86%#1"'/D(D!A<%9:4;><;>2E*/AC@F$@>EG!BG!@5/1$%5$.#@B'@=
@r4148
NGAGGGNGGTCTNATATCGTAGATGAATATCTTTATGTCGAGCAAANCAAAACAGGCGTAAAAA
+
*'#%!))$+)(($)'"$((")&*(%+)#$$('"$)$*&*!$#$+!)$"+!##!#))%"$#"+&%
@r4149
NGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTNTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCAT
+
!C/7%>6)(/+&C2.13!(15@<+/('&17%=6'3H(:B=(92C795*:/"%)6/$+/5=&DAB=(12<>;':-?305.F0(HBCB*('C@+)9'600?D""4/)!C?++&#"4E++G:;:?1/5?&@G46H,-#H!%7*))D17&/?(%#84?EEE/51'156'D-G("C95&DCH;/;D?AB>B-0=/-%
@r4150
NGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCGGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCAATCGNTCGCCGCGNGGTGACGTTACCT
+
#/%1.449:#.<6E!4$)$.!$62.?B$F%&-$1E+D6C<56,6-$0:6?+.5B/5C.!G3.9>FG3C7+"<>F'B)-7G?#8#-;)//H-?#)975%"49:99$16<3=
@r4151
GTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGNGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGNCCGTC
+
:'C6&F17B<B*(+?=*D=A2@0*/:81<3F)C5%.8,$8+"+8EDF-"?0D%*CE07<%.4(-!94H3H-9,3>3)6@C%?=*D/FC1F
@r4152
ANANGNCATNTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGNTGTATGGCCATAAAAGGTCTTGA
+
')&!)'(%*$*#+&"&*#+%""#'$)&!)#*)%*'*("!*((&#)&)#"")%+&&%!('')*!!#!&)#$#*)!+##&#!)#+'$)"+
@r4153
ACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGT
+
8/)5H*F527CE>6%,*)<5<*,,1/636<198@!5F!,4F7*1.#2H3'>3HD*?>7%//
@r4154
ACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATG
+
'<09%D:''H$+6'C)&$+-&=E=&&+;!?*C&)-,HA@1&H>G=FA>0?$F9-B<8B0A6')80++-77-H-AF5+&'.>5G5$B,,)1F*2@!=8
@r4155
ATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCAC
+
HG!)E?5(/E!8E@?!8H?=5<F<#F?"E1%5'>?#/1D)C9,+2F-,50&;F?A<;F=4'2
@r4156
GCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTT
+
%=A,@!*EB1#B*4E1;B$C%!A%=&A,!3:E0(,2+7:D*>*/B"B8G19AHFH2%D&5B&-:*!GF331
@r4157
ACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACC
+
E9C/0;72:97H,H2)6:!@+%DE).CH-*/%?/77)+:GGDHGG>$*&*E3#=$0/-'>;C$)&?%$;&;*'6=9$<H:0<1#,!5>5+?D9H
@r4158
TCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCNCCGTGTGGCAGAGCTGAAAGCGGAGCTTGATGACACGGATGAAA
+
&(+((*()(+!#)')%!+#$*$)#"%%'$*&&#+%'"+!"*%%#"&($(**#$"+&*(&!)&#*!'$%&(**'++("+$"&'*+'%$"$#+!#)%+("$'("$##+
@r4159
NNACNNAANGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGT
+
'"%(!%'"&%+&!)"+!&$!$+&%'++"%(""#$'!"%'&(&"#%(*%%*)%&
@r4160
ACNNCCGGNCGTTTTNCNCGTGNANANNGGNCANGAGCGANTCTGATT
+
)$($*)#)!''#$&)!'&'&(#*&#*"&)(!*&)$(!&%$"'+#"*)'
@r4161
TCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTC
+
B>"8/,:)F-C8<C<&&F@-HF!E"E$,@-0,D!8010:?-6;9<#9(,7H);2&
@r4162
GCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGA
+
3G*F6)B&("F6@D(9--@28<F@*5'7H>6.41-$-'1E+)F);884@D(%0&C*,.+@@!(.$0'%E?
@r4163
NGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGC
+
!2-+4")6/EC.1:1*7=49G!;CDB,40C6?#6>=-(3</+#'+1A$&?":FFG/?=:(5A"=5&.8$3%$
@r4164
CAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCC
+
=E?;.2.&?&>66D=/@$-8/'35,H;'+2?&1G:6(G=7
@r4165
GAATNTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTACTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAG
+
'('($)+'*%*)*+('%!%&#!$&*!&+)'&$))+$(!++%%'""!%+'&'!$"+**)")$&"&*#%&$"&!+"+(&($$+$#*(+'('"(!)()!*#%'*#+"*"%(!&)$"&#)!!'!!%))"#++!!(#"#+'***+'"('!+&*''*(%&"""+'#)"&##)'#'&+'*&+(()$##'!#)&!'$%%!''+"+"$'"&%)(("+)"%%)(()*%'++')#!'$"('"+)(#
@r4166
AGGCTCTAACTATTACCTGCGTACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGANTTCCAG
+
BH-6D.+'515>6"6-A?"HB,9$9HF<6=3%?8C"6G>!DG>A:GH3HE!A5;G1B$.&H-,F->E#@6.E%%'8,0
@r4167
GCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATT
+
?&*/!A'89.H!>H*AF'!.@/H(/F<2;)5+D4GC8/C">&GH1)!*"G/(:B/3;(6*+
@r4168
GAGATCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGNTTATGACGTCATTGTAGGCG
+
'!'')*)+)&)!'"$!(#'&+""*$'&!"%&$%$%*&#)"%+!&&++*#(#)'+&"&*("(#!(!#%%
@r4169
TTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACG
+
D6%"H5>6-(=.<:'607)9>.'"1'EF")G,*'?'D!G+G$9?;H!"1133E+>/<EG&$H74+8G"1CB1E:+
@r4170
ATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTA
+
4'G9:E>/G5/:HH;'G6E2%7B&1",C76F#>7)%);8<?@&9?H*"*E;;(C+6#.<.+(+F#@?E.H?%?55
@r4171
GCCTCACGCAGCCAGGGCAGACCACNGGGGTGGCTGTTGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCA
+
*D84=AA(H?E8($6,7;#GA4GH:)H?6(&<D$=6)+E&!/,0/F03:?7+7$'>'&G3H/%%9<B//E$<D=H3C%@B
@r4172
CGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCA
+
/8/;>A3A8/D+00!.6>%#B-.'-G!-//,87CH**0<8,/
@r4173
TGTCAAACGACGCAGCTGAGTTCTTTTCTTTCACGACTTCCCCACACCCAGCATG
+
+#%'+$(+'+$(**!#"!"$'#+')%&!%")(%!*!'$+)'+##)&*"$*&&('&
@r4174
GAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGNCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTA
+
6)FF53!G%!<F0/AH91$2.(>3#*70A6-:$<>A2%?"@%FBBB#?1??F86&53&):C1:#16&.,66383$=2CB'?@91/6%@4.=
@r4175
CGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCCATGGCCTCCTNACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCNCGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCNATCCGGGACTGCAGTGTCTCCCGGACGTCATTCGGAAGATGG
+
%D->=*2%E$)!"ED"<6F2F7-/."06,"*!89&&-;1B7C%-3/83E!(*E12AG@-B"E:6(3)A8:/:/H*-#.GH()H6-<A2A"E25+(.>@)H/G5,A2?1.&G3%E"5$#.:E8,6==!784./5)'<*#*D,5=>!FH)5>;<&H:E!0;8H;"A9=EA)C)*H9C*=!@/"/'+4",F
@r4176
CTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCNGGAAGTGAACGGCACCGGGAAGTGGTTCATCCCCTTCCGGCGTCAG
+
>+A'/5E;(7#3?49#93>;:5<<'9>++G66./H<3)8>=0.('2*!,$<,.>*6<)B=35#%+)$'H/@)0A9#D?#)).H7EFDD9,#+$.CDA+1!:3AD@
@r4177
CAGGAGTCTTCCCAAGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGAT
+
85&%3&..18&,#39,F&%AA&@)G>(($4F:=36"-/5)E%)*%H**32(4G8196)4:2(-#:4<?5>%*4>'5>9#C-7@9:*!C<,F2%?.$*0<G,2>4#"8&9E-'%8*5<FG"D)AH'!3?!0&$*(:$<7+<
@r4178
TANTACNNGANCATNNNNNNANNGACNGANANCTGAAGANTNTCCNNNANAAGGNAGNCNGCGNGNNNANNAA
+
!$!!!$$!$!"#$"!!!$#$"!!!!!"!!"#"$$$$""#$!"$##!"#"!!"#"""#!"##!#!$"$!"!#$$
@r4179
CAGNGNNNACCGCGTTCAGANAGAGCCACTGATGAGGGGAACNACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAA
+
)$&#)&!(%'#+"'(&")("")#"++!#"&)$!*)("+&)%!"*$#+$!&+*+*%%*&*&$')*"'#$(((+'*#%%'#+$&**'(##%!'%)""'()&(
@r4180
CTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAAAAAGACC
+
=08-:%::#:?:F2,4!DH91:97>790#C29D9'?2:093.&"4799*+!6)":*D'.B?A%
@r4181
TCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCG
+
//)3"66ADE&)7527$"+'-1C9@>7+41.%&/9*D'*F&HE)0;+-A5A)!FD&%)/6G:"/6,?@E@33H7=9@G
@r4182
CGGCGGAGTCTGCTCCTGCTCACCANCCCGGAACNCCACCGTGACACCGGATATGTTGGTNTTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGC
+
1#.):8A*F5G/1B@59((!1(1H%9:)?H+;1*?;6+.)$2?(HB,=&7D>%%&/F/%C$4)<!>$F7&B4E%G30/22/.G>>7%1E06G7&-<?
@r4183
CACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATG
+
*=-6#;!'"*B<&A:$337-;2,*277AF?5=4*@.4'%<<4D=3DG
@r4184
TNATCNCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGNAGTATCTTAAATTTGGCGACAAANAGACGCCGTT
+
#!'&)!%+##%&(##(##'(+)"&+#%)'#)(&!)*&+$")'+#*!"""*##***$++%*##+%'&%*#($*""*%()+$&!!(*##"!
@r4185
TTAAGGAAAACAGACAGGTTTATTGAGCGCTTACCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCANAAAAACCCTTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAG
+
F/@,=!&F8:%*=*DE@$79"C#7C$6;"31&)+9@8/,*(&!25,&?:)$?+-))A:$H#((:F"..G+5&'+!39CF87H'CC,D(;2"*&8B=C!:8F0)3!+97-9DF:B?
@r4186
GTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTA
+
42E?H;81+%A,EE(>(%<B:BABC+&#/8D4*6(A9B!5/3.)-?7=-B,8F=G>+)-4$<,B%DB2BEGC2'0""4.<A2/,.F5A)!"D,&3?B252/,EF?6<(&*==.&%3F2+>
@r4187
GTCTTCCGAANGAGCTGGGGTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGGTGAAACATACTGA
+
7(:*3+8!B@$B/.B3:C@A;<:G%%=$-D7<H6?)8#?H+8G(.-?('$-@%G-&?1:>EH#;"8%-F7/-
@r4188
CACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGANCGCCAGTTCTTCTTTCGTCCC
+
7<,-?/DD;%GA,!+8.+<;(/95E)27/!'5.2=2&@H3&,A81FB,,E-4#$01F5/EB!:9A+*2"77=#5>1BH!1?A'-41=8>E)>8"%"2"H?'22:#H!-<66%&+D$1C!"<2-0BG%82
@r4189
AAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCCGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTT
+
;2>C:*7;!C:!$B45)('@D1(84,G",#45+/DDC;E,>-1-/=$G#63,=-*C35B>1@=*<3/4%F354:=G.F47BEA+<=9.$>1@6*.&&9)6)24;,#37;8G#EEG-6#,.3-3"@;23:D0,
@r4190
TCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGG
+
A#"$7/34#B;>H'3,-9%E6<61(/?5+.,)0HBB#3!%320*8'5D0'E6$/!7FF=A/++<9D66%>4+,,31!3GB1F&<)(1+H*(<:,.$<+>6H+8*6"%!:<?BA*
@r4191
CCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTT
+
'E2%#=0=07*&2D<62C!)-@%#+8,@5+,+96(/03;F<);!$>+9B1%G3<"9"A>1<!/%<>5"1F=B3%73C
@r4192
CTAGATGCTGATATATTTTAGAGGTGATAAANTTAACTGCTTAACTGTNAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTT
+
'+("'*%$!$$"''"'(!%&!$#)#)"#!""*"%&')&$)*%%+##*&$'"&*&"!#)'!#'#$'#&%#"&"#+*)&(#&%)"%'%*)""!'+*'*&"&"+**!$&$'##!($
@r4193
TTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGATATCAAATAATGATNTTATGTTGACTGATAGGGACCNGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAA
+
$('+#)%$##$*(#+'*&(*)""()%(##&'$!"!()&+)!$+#((*(!)("!&+"$!)#'!)&%#&!"$'#*%$#(%&("!#+(#$%$*""+)&#$&)&*&!"""+*$"+#$#(!'!%#"!*#$(%#!#+)""$"'(#"()$+)!+%"*'*)(!"+)'!)"%*&"($$#*()$#$)$$'(")")"'"%#&&'$(###%'++&*###!)'"&&%#+'$$%+!**'#(!#!!')#!
@r4194
CGGTAACGCTGATGGGATTCACACCGANTCATTTAAGCCTGGCAATCGGCATGTTAAACGGNGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCANGGAGCTACAGGCTNCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCNACAGTTGAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATNAGAAATACAAGAATTACAGCGACACAGC
+
?58<++=,H&!,43A2#"!461#*:E:4+0E>(C-;5H20;:*?EB,#>6&3!<*0.06$;=HD0*54H-46=AA9?E%7?**+3+G.*B-AA2>3ED+@:<$!C-E**&>"?%B(.>8E#)"5#'2<<@4$9(%B1BGCG20:!@82=-75,C+C9;29:;?F+#,1E$.:&->;,?;/1+2A#3=H.,D3><E1@'64=4G!CAG(7/;;@%%$!3./$+%7<BD%!#BG
@r4195
CCGTCNCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTNACTAATGNGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGA
+
*)+'&"!*"$*('"'"'!+#(((*!%)&(#(++)"'(''"$*'&($%)!"%#&&%$'#$)&%''&'%(+%+!#+()&!**(!'%$"#$#+&''""(%+#!*#*%"'*!))$*$)(")+!+$!'!$#))
@r4196
TATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGC
+
.1>=?,9@G)0.3@<3A39+=;-H"&4#711('@?%B(&;D*+."@B82&2956/33+!C:BF+,
@r4197
ATGAAGCGTGAAGGCCTGCATTATGTCGTGATNGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAG
+
3;F7H)5""*4'9F$@D-3:+'E-A-$H*(C+.+1?.>@$04:(&F@&+F-$E;D$B,74B.G>'D"@.#D"2?7B.1%72
@r4198
CGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTGCGCCGGGCGTCA
+
B#'50F)29@A#E+<6(&C50G4B35H7!/.$)<2.+;3'0EG</!B"
@r4199
ATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTCGAGCTNATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGNCTCGCAATCCAGTGCAAAGCTTTGAGTGCCACCCACTACGACCTGCATAACAAGTAAGAAGATNGCAGTGANGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGCGNAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCNTGGCTATCTATCGGCTTATTAGTANNT
+
#)'+''#)"*!+$##*!%!"!*#!'$&%%'+#+'&#!(**(!'$!!($*#*'&)#%$$&%((%"#%)*+%%%%$!+*(*&(%*&$#)&&((+!%)!*!+*!%)&*$)&"+!*+&(+#)+'%'$*!'*#%"&"%"&&$%!("&"*(!#('$*%$%(#!%&&(#"*(%"""$&("%$!))$$$$"!%+"'#!()%&$++(*(%%%&))"#&!#*+")'(*)+')''%!)*!))+*+!%%&+#'%)#''$((!!"*#$'*#+"'!*#!%*+#"#'$#!"!&"$%#*'#+"#%'#+!$#*+&*'""**"'"$!%#""'+!'+""#"#)&$++%)&*!$&+%"(#$'$*'(+&##*#*$%!*$)$
@r4200
NACATCATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCT
+
$$$%$+"$+)&$**!%'$)#$%#)$(#!&"#'"*&*&$(((#%
@r4201
ACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGG
+
9%8$3=)(&,D*A'?64=(1.1&@%!:(/2&,2A*=**F)2F4!:./79.E+/"9@%F,'&9&764&,'$>-.G'C.>50>6F=248;&3,&%/B-@'582D
@r4202
GTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTNCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACACGACAGGAAGAACTTGCC
+
2"9*1/6+%7!>.#>"/E0@E)G8<0$C*,@'H46C7E670(:=)!(?8855)A(C+,6=>*G#'*6B('%C#*!52!:!;(%)0*$6;9F3!85"/07!G2H3(;$/#HA:>>D8".7&8#?;,,;&C(/()16'E#*./0A,5+FBF-;2-7((9;(%+:/*0*>?3#002
@r4203
TCTGCGTCTTCTGCGGATGGTTCTGCCACAGGGACATCGCCACCAGAAACGCGCCAGTCCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGG
+
07+D80=<(:,<(;3D&GE<-.H<*99*+<46)<2>'0@18'(.@A<-;$@<$'H7+''F+(&.&2-4!E#<!3/D,8H+9GFBG4=#=;+9E*&4)D6&18.1H8..'16$#:FA.+>!BD4872*4AF/.839F<:(F/)F4571"$E&07:.-
@r4204
GCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACTACAAAGCCATTCCCG
+
0/CFHG5BF$%*&&B=6"*/5C,58,'<E+C*30&79!841*0;:B2)H$7(>-3;H1;G',>FD368@C1!/('0+#/B2+6!G6CDC)8=(A"G:H
@r4205
ATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACA
+
;%D0(!H&;3E7$@:#6+.;'&E(E7?GHEDB':*()AB5=9H<8CE=H(+D9D0'FD21<*
@r4206
TGAGTGCGAAAGCGCCTGCCATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTG
+
CD(BFGA/EDE7$G%>@#?7:5*B=36/4.@":*-&/+.%-G0)>',:?5'98-/&+9)!GFF5-1-/F(/(1(,D122=$3D+%''*>B
@r4207
CTGTATGTTTTTTATATGAATTTANTTTTTGCAGGGGGGCATTGTTTGGTAGGT
+
@06-9$DF83@2%@0$6!*:%8F=7=$)<C+1B'*2=:=C"C"2.-9&H$-2=:
@r4208
GGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACANAGGACGACGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTC
+
>G66%.)>D&9$@>(D4%G;05=>)0H5:)>("1(-'>;.4,>5?17C%9)=.+2F!9'@(;E4"C-+6-&?273EGCBC?4#!96HD32.)C<*:@.,D;A)?9B(F?G'35<-'1(?1C?EG;)2H31E07%C6G'7G66-E:DA%*E-%*@BD1#74*D;4#7!9!9;+)C1AD/C7>E
@r4209
ACNCATCACCCCCAAGTCTGGCTATGCANAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGNTTTTTTGGTTGTGCTTACCCATCTCTCCGAANCACCNTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGNCTGAACATGAGAAA
+
'*!+!!+$*(#"+$$&%%*)*&"%#'%"("!$$*+"'$*!($&"'%%%#)+$"#')*$#*&+&"#$*)%()(!#"*&"#("*("+"!)$#%)")%$$&%"*!#'"*!#('"$"(&)+'(!"$"%(!&+*)++%*!#"*)$+$'&*++$&)'$(#(!(*(+(!##&%&(!+'(&""!$"&%&(#'!'&())&'"!!$"!&'*&*)()'*&'(#***+%"')'$#!(%$%*%"#*"("+$')($'((')(
@r4210
GGCAGAAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGCTGCNACACGAACCGGATGAACAAACTGGATACGATTGGATTCNACTACAAAAAAGACCTGCTTATCTCNGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGNCTGGAATTAATCACATTCC
+
:H,D.*<1$14HC131!3.'"9)F%#6D@">'G>-<F%:>H;!642%!5/7D0.#*!6,2/!$!@"4E*F:D(D"7E>B+@!!:7&1"&+7"=%804':0$@>13H@>1B%FG!->44>&;&41#>:B%@B'$B54CD/:#52",D?/(%EC.$*EC,;25-B3&;2$%</)2@.
@r4211
NTTGATCTGATTAACTTGGCTGACGCTGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCT
+
$<DA0G=?A=+&9+=BG3"E44#$0*9!>)@09'@533(,E#<C6H7&&G4BFA-/'(.E@//*&#+.;="@
@r4212
ACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATNCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCNACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCT
+
3@&<$D>7H&A29@&G0C;&BD#-1@HH9-/&?>@'H/DC2+8H!8175G-+HC!?9B!?3(*?.&G',C?562/(HAE+%&E..HF@F<(::.;B0;$>/;>B:A8F!&9B%;9/)0;!/"<-*D*-1EA=%77,D49?2EH4,*B=*5%/<"5%3"')2.@B>$7G1H0?D-96<5FD"'6'@':#!D-F9$/*C="7<?44?/!55B%'24&052F*=#C%:BC:=1"9&HA'+!'5-H,E*G0:G?C7&D!F<7$687=!%&/B7D00=0':(4$:4G3=7/!=&2*8;HAD'DE<:#D@-,)A?.E
@r4213
CGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCC
+
<1/,HAC$>H34BF$#4A%G,6+9(<<C#3'0A(:!;,+(,>!2
@r4214
GTATACAGACAACGGATAACGNTAAGCAGAACACCTATTTCTCCTCACTGNATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGG
+
H70+2#5>)3,(0<&B/F;>''(AF'%+<=8>-9D#//,AEB>A)A9"0C8D>@?(2#BC+F@5D-0"9.E>4"0)=7;$B'&?!0#6=&5)#':45C9.'!&*A<;"8
@r4215
GCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTG
+
64DG:..;"9A45./@@3++E"";:F3'@F%'9#A(<?F)7:*1C!@0,B>E(H763H5?71/;0;;**<35#.,GGB'FG3!!?><5!37-+>!2'."0
@r4216
CTGGCTGATGAAATTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGAATGCACGTAANTCCCGTCTCTCAGGAGGGCTAATGACCAAAGA
+
;&5F;GG/)(2F+>.:EE4,14:->C*!#2=892H/"@H0@55-3>=$7="'&<1'C&'8>:3/<D"&E;C@,";0.%>/G"#E?D-+.&:?6<B56+/3$
@r4217
GCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTG
+
/#$+F+0@"3#,0E/9,/9/D=?0'"=#G9%+3!$5A+9$@4+*9;9&8,7'7G=;E#*@1+6<*H#')F8H'@>@0F9.E'(#F3#>--HD6#*
@r4218
TAGGNTTATCTACCAGTTTTAGACGCTCTTTAATATNTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAA
+
)#)$#+*%'!$)!#'$%#)+'+*%"&+&$!"'+"!'("("""'&++!)+*%')#&)+)&+'#*('+$*#!+*(%!(++'(#(+%&#"$'$'#($('+%''"'&'#(*#+#(*'&%(
@r4219
GAATCCTGAATAGCTTTAAGAAGGTTATGTTNTAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAAC
+
$+++*)"(($'&+$$%(%'+!*&!*)%'&!"$#&'%&('#*#!+*+$#!*%#+%$(#"*!+!)#$!&%%!)"##"
@r4220
TGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCT
+
&F&#+@*+G-E&#F6B0@?@#<)"1*49C-G%C*0+=E(GG"DC>7
@r4221
TTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATC
+
E@B..+-:"=54H-+C!7-8>61?H<9$H0@*$B&A:"/<-&'A&!);,,7E)2('.(FA#>5C8E=.(/C&25'D>G)=**B>A2?=63/"7=1C2"E&0:27""
@r4222
NCCATGACCGGTGAAGCCTTCGATCCNGTTGAGNTGGATATGGGCCGCAGTGA
+
&9G7-+.:!#$G).(7@D(>6@.;!:1(91@4!H(+.($D2>$B?+ED/G5@3
@r4223
GAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGG
+
H2E4"*5(.+9<90%>H0EH3$5F0BH?BH%53!EF*-0CA@6*""$/D+F/F/5C"G<6997A,(,16*4!)?$HA-!$?%
@r4224
GAGCAAACGAGAGTGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACTGGGCATGGCGCGCA
+
$<;=3F2:0F(!A4(H=F5(B5#EE17!-D2%+-11H-#;>1C#3*CD/0@#)>!G6+E>!<&96!#+)5&<#'9@
@r4225
GTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATA
+
,?H3E=67.7;A:<E">$$5+@;B3%:0(*0G(!&*9<9*48'/79BG1G2E1-'C1FF?4@B'$.7AB3F@A/G/5,.487C$
@r4226
GTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAA
+
7)B8:/F7*2A/C&B"/C;<"/:#"4"H/&/%3-.661:23G79&8.,
@r4227
ATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAG
+
$*/++"9F?0A0G:>2!($<'A;G9,22:'A'F673'-"?!0(76C(D;>6;(1$(F14<:6A/.?!7566>=0844+3F>3(,*,AD('D"2;<4B!E.@<%6&<-/<G"/+;=7<
@r4228
CCAGGCACTGCGGGCTACCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGC
+
#+")$&&$"#*$(*"#!""'+('+)%)!*$*"'***+"%)"$!+(&)#*+*+$##$)!*''"
@r4229
AATACGTGCANANAATTCGGCAAAACGTGCAGAAGATATNGCTTCANATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGGTAGTGCAGCTCAGCANTGCAACCAACAGCACGTCTGAAANGNTTGCTGCNACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCTCACTGGACAGTCC
+
D"7#$.#$!<E.60!1B)#-;>$6$FE"$E3=;E?;7H'8%4:+?74"4@0!3(!$543H1$(#<*7184$/B66%3A5')D/-HE3,-!&1/"%9%+)GBD3&&&.0*42E>FH0.;B+:G)#H.C0+DBA2A,!/,DB@&$0((:H0<>'CE?+(,E21')(:'D7@$&'9(,8=3F7G(5)1,:1$$.>G)#/*$B<9E55
@r4230
TTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGA
+
=$G66/3%@&C1E#,=3(!;/@&C(!H?=6<GG-D+'.2=9
@r4231
CGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTAT
+
&+*$"++'*")!%+))!$"+$*+#)#%*)$'!)(%"&!!!")""'#*!!%)$!*++%)+
@r4232
CGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCA
+
%96GGGA5;"D!C""G<F,-E&0<G0;%B;D'F*!E6A3-2*"BB(&6!2(
@r4233
GATTGCAGANGTGACGCGTNACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAAC
+
@;D,(1E5:/EE&?+A%50>*!&7F-++3!$H34+7+(D9?B-3F.$8+56E$:#)?-159-4HC)?.+<!:@5C:@,E%(3267<22,A;4;F-B).@B(0F)F5;E5:;89BHF)<
@r4234
CACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCNGGCACATGCTGCACGGCGGTGATGGNATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCG
+
64'><!0>&=:3A;H!(H6!?<D+"((,A7AH$@>A=H#>%A)G#>='1,+7=E@!+/;B<,)#+)>"EH"=D(=EG!@%%<H>/20+@#/)<;,/)%<:!@(B2D70-%0!<&7A;:6+))&7'GC8E@-=;
@r4235
ACTTNTTNTANGNNTGAGAGAATTTGTACCNCCTCCCACNGACCATCTATGACTGT
+
#*!&%&&%'#%%!%(%+*+$!%)$!+)$)(('$"*("&&%)&$&#(%!)+"%)))'
@r4236
GGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATG
+
//)<#!@='1%$!9-/)@#6=H6C&3B@C+&,6#:GAA=*-12+,CB##<'
@r4237
CACCGNCANTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTNATAGGTAATGACATAAGTCAGAT
+
'*'()"('$+"&+$$+%)*!+($#+&***'$#&%%''"$!&'*+%+''$%%$)+$!*$(+&(!**$%$$
@r4238
NNNNANTNTNCNNNGCNCNGGANGGAATNTNNNATAGCNTNNGTCTGGANNTNNNNATNGCTTTNTNNTCNAGGNNTANNANANNNNNTNTNANNTTANNGACAACAGTCNTCNCNANCCCTTATNNAGCANNANGNCCGNGNANNCGNCNNNCCNNTCNTTNTNNACATNNGNAGTNNCNNNAAANGNCGGTCCCNACANCNT
+
"!#!#"#!#"$#""$$!#"##$"$#$$#!#$$$!$"!$#$#!$#!$$!$"!"#"!!$$"$$#$!!$""$!$"###"$$#$#$##!""!#"$"!#!#"##!$#$$!!"$$$!"!##"$#"###"!"#$!!$"!!#$!!##!""#!!""#"$""!!$$#$"$!!!#!$""!#!!"!"$""!#!""$"$!#"#$$#$!##$$###$!
@r4239
GGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGG
+
GE,.=%:8"8",6B+0E#)8";B6,<18=@7>ADA53H?H
@r4240
CCAGTGAGGAGAAATAGGTGTTCTGCTTAACGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTNGGTGCC
+
#(+!"*%"$%"!+(%+)!'"%+##')$)&&%'(&+#'+'!%*$)+"%%$+%$%%##)*)*##%)$$'+$!+)#$
@r4241
AGTCGGCCAGCGTGGTGCTCTGNGAAATCGACCTGACAGAGGTCGGAGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTA
+
;$9!?"F?:0?/0"DFB=EA##/),1F&29*G@:+-A)H>*@F&D.?-2DG&*"9-E+%!,4-/D+:8=CG/%18+8*F40%CG"9F528:$$?H&-C7B=#2"425H+.A6041B1B8'=3,-D:;
@r4242
NGACGNATAATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAANGTTTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTNTCAG
+
%)())"&&#+%!*&&(("$"%$%#+')++')&*$(")$&#**%*)#+$"#(!&*"$!*&!%$++(+)+%!&"#!'+$!+'!**!#&)&+$)+'!+(!%$
@r4243
TCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACA
+
4;*4G11%(8+F#4666963>5,51-#&8'#+?%C1@-*0)2039',;E&;!%$G0,653%$<C?@)281+E!.D6>)5DE-(@=B6
@r4244
NATCCCTTTCGGCATACCATTTTATGACGGCGGCANAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTG
+
-/+1-3D+54.,E1B;0C!@?2'+:&&@:C--;'@@A*6F"%&H6?>,#=8@?7)5'.<E>4.9#*E,F;D?+.8<F#ED8?'%/4>9B0C
@r4245
GGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTC
+
<&0A*!4?F<+7>D.6<(%3-E'6"=AHCA(">A'"5D(<'=)'&
@r4246
TCGGTGCGTTTACAAAAACAGTAATCGACGCAACGNTGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCACGCTTATATAACGAGCG
+
-76F>>%G2($7#3-A6-:'9,6E2)'DD?3F@@2B*)@;=;D)@60CC"(9FF?B4)%("2F01A#1C/A,7"G!C"6D<:2,)4(">3?:0<;3:%%8:2"0H@C*@2+C:G!9:
@r4247
ATGATGGAAATGGTCAGGAAGGATGGCCTCCAATTGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATNCATNAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCNAGGC
+
%:%F..42G'D*>BB))!HG2(<>,!;6F&F&*+2<4,!(%3<169D-77(0("B%.#$&0#+;*9=B4=*0F91F8&&1.(9;!@H<:!-AF:+0=9@B0CH",.%4/&,A4%B9+:/2(=G%0A#E:",%?"9>/:A(C;4(2781@37?%@=2(D<
@r4248
TAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCAN
+
#09"@$(/4E"2,"0#"2E&&2D:;.,:@:B)3@1';,G'"1
@r4249
NCCCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCANCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAG
+
##"-,+4,8H9-*"?F>;A(.GC0'GF<.'$!?6E:+('"*8HAE%&.84)H0=D,6%5#C#6FH.G,+;"@65:35&%3.2*'D(6<$"F)?=+6>E1!A$/9+@<@=:H;)E&.DB/=5'
@r4250
AGACTAAAGTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCCAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAG
+
'4*466-"94/F++*)(CB7(#0,H(279",3$9H18+-+:>FC:1-,7<@13*9&<#39-3'(<?#:E*)&:,AHA9:;A/&=>739F#""%>@1;96!C.(&?6(,E<"9*>81(41)<#2>'(,7-//5)>A:/H02?9#7;@)<10E)**@F&=($;''2@A$H#:H.H3#$,87,-45
@r4251
CGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCT
+
')-G38&%5.C'=8;!B@D*"2(,!B!/!%"88!1*?99G==77.&5
@r4252
ACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCC
+
,E63.A6C&H<%</**24G2FAB<H7!93(%.9@5C2&>D,-H284)-+'>E0>/A)=;
@r4253
CCTCGCACTCGCGTGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGANANTGGAATGG
+
2?.D*#H75/CA1F>!H!:0&;-FG6-,A-,.H38:H&@B@:A&C!)1C2:+819;2-9C5;$;6D*4+4C"@#$G=752>98,";G9@8930#2,=)/3
@r4254
NTNANAGATTNATNAGNNNTAATCTNCGGCNCCANNGNNTNNTCNNTNCGNNNNNNNNTANTGNCNCNAGNNGNNTGCATNNGANNTACNNGNNANNANGNNCNCCACNGNNATANNTNNTNGACCNNANTNNNANTGCGCANA
+
!$#"!!$!"#!#$$!"$!"$$$##!!$$!"$#"$"##!"""$$##"$"!""$!!!!$!$"!$!"!!#$!#!!#"!#!$#"#!$!#""!"!"!##$$"#"$$"#"##!$#"!$!$#"!####"$$$$!"#!!!$$!#$###$##"
@r4255
TACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGT
+
C,9-2.F4+D"21&7!0?293?G+D0$)#8G<@6$09*><2?8E+F-?#9E&A
@r4256
ANGGAGTNACTGCTCAAACACGGAGTAGCCGTTATGCGTATC
+
(#)!&*(#+("*+&##+&$!)!*((%!$'%'%%!("%'$###
@r4257
CAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATT
+
$;**CD%4-9EGC97$!0"-H79-.:?@!A,%(4F6<"<0E7=%*+FCA!26151@=
@r4258
NCGGNTGTNGGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCNCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGT
+
"&$%%#&%#+!&&'#!$+#%($(""!'%)#$"$%$"!)!*%!)%$&#'+"%!"&%)(+(%#*('%+"&!'()&$+%%)"#(*)%++'$$
@r4259
TTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGGGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCANGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACT
+
.F%7G=$'4CCED!)@199AE50CFD:!8H>G!56=*9>-'/0G)8**?@79FC<&A82A'!C)8%7H*A)9F-#(>50)E1C4B+=D$.869C8&D;9:$98('/<"G,*>,A#@B=-*'6?-B%;9<2($,GG('B),+0-:17%7C(F4(D<&.A2*;4*)H5@@A!#G&<#:-#"/0E"GG"5,.)A+/+E2"6G,7
@r4260
AATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTT
+
G?!AA.C?,C4-,F$:B7&8*'6<+'&,'"5,41#DA(>/A7"=+-6G&.5)0BH')HD&(4E-<53#'5#!+D48%/@D#.5!."?B'*@3&448'#?D$E%#0#6;B.((D7@D2"@1@1'G/'9<0(+;>C1(64:?GED(2D,DG,?';987+>E/;G9/991E"0C$0+"8"H*-*96169D><B85?,GDH#"":6/AG8?45*(,'C('#&2:)G'-A!9#(&)2(38:,D3C<%B-3%<$:*"%#D.#$C.H:FE<48$?%E8DDE916$'B!/(??-&/FH%!?99
@r4261
AATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAG
+
,)3A!&.<6@;'H*G59''D27*.DDE19&1)85#>49B4)E(6F!46A,E3E
@r4262
NTGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATNTCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTNTGTGCTGTTCCNCTGG
+
-A=3)09!01&C/5/5':%B(F>,G0@6AHF)-@.??D#8$$4';'$2E/+-A)2)F!-H>GH?G1D(H9H>B)/H,'<4$>.CE'9%0H:@E/?$E"4.B;'<9$38)(53<D9/F%D$7/728=1%@*4H&&B1@HH)@<><+A(;F6;',!-C5-E#9*"1?,H-FG@@!,>F<C95!4H35G=E0:62!5
@r4263
ACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCCTACCCCCGCCTTAACCAGNGCGCTGAGTGACTCGCTG
+
*$6))F-7"&;>..@46>-DD0<"-A'83H0FB,>@*1B0H"'-11FAG;*8D/184"/5-+9!/+$>F?7<E/5"-91G4-$=B@B=-57;.B0/>>14%+<DH;?A(/660>+28*G3F93F@4%$:,#=5-C9-.=%<20*CC7?0)#+92>%":-&A,,+84GABH!188:?)G>$!#*DE0=*-C3.''1E>)1HGB4.+0G2*.D+;"<5
@r4264
TACCGTCGCAGTGTTCTGCGGAAACCTAACATTGNTTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAANTT
+
'++(%*(*)+"!*$"")")!+!&%#')"#'$())%)&#"*#'%(#%'*)!()!%*%&!#)("#*"$&)'%*('$'"$"$(*%&
@r4265
ATGATTCAGAGGTATAAAACGAATGAGTACTACACTCGCAACGCTGGNTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCAC
+
+!&**"!&($)+'*!+%#''*%&!"&)!!#$"%!)%&+*&$")*&+#&+"#%#)#(!%!$$$)'$&%)%$(((*$++*)!*$*#+())&&('
@r4266
CATCNGCCTTTACGGGGATTTACNACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGNCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGNTGGTATNAGNTACGGATTGCCGGGCGGGACGTCNGCACGTCCGGGTTAACGGCGCAGTTACATNAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGG
+
%%*+&!($'%&$&+!("$"+'%))!%(%#$(#+*&%(%&+!)"'+*+'*!)+$)'#")(#(#%$+!(*#%"(*#)!!+"'%'*)'*+*#'"+%%"$$(*)&''#$+'"%!+++!*$#$+")$$)!&#"$+)+($+*'#)#+$(#&+(+'+%*)("&)&++'"$&%('"')%$$+)()*"("!()'!%(&)*"('(+**%')&&$'(+')$((&*'#*(#+'+)+(+(("$$#!'#++$'#%*&+((%)!)#!$)&
@r4267
CANGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCG
+
"*!**))+#&&%()"'#&+")!+#&"!)''!&((*!*(*#(%(!!'"#%)!&+*&(')&!+++('!%&'+*!+&!!!''(##"#$!&#*+!*(!$'$'$++!$(
@r4268
CAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAANTTCGTNTCCGGAACTCCGGGTGCTATC
+
@G*C<#B,0A"+?@A=.:<$EE9<,&0E4E"-5?!.3937!H%D2H95C0?<18%D$5>##-C).3=
@r4269
GTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGG
+
-:)+07'4!?>+B1G.59+&C+&#9CD)2#-845HFF39*@970,'."="BAD83*7(
@r4270
TGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCG
+
C)E'1@DA1F"@+=DD)!(@@1;5;D-2*'/=9?>;%)"+?-0/D!AD()G,CB#*5.@H*.+96:?6>4!!).)+(F40B=B%>89&(81FA)?D;+-(!"5
@r4271
GTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCNGCGCTTGCTGGCATCCTTGAATAGCC
+
#-B504=3(%87'',?,+=1H&3>5,,D2.&&'*(DB"=?3B>A1C/%;@/8:-,-0,5-,2C2A
@r4272
NGAAGCTATCAAAAAACTAANTAGTGATGAAAACTTTTCANATATGGAACTCATCAGCCTCATTTCTNAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATA
+
%?=-4*>-(7,;4:5>1498-$=,E'B5*A,1<-?('*E;7.C/4G,*DCD>#C*'4-!'48@C;),B#--"$#+A7?:';98(+5D$7(H*.BE;A!)9<4,%/H!/'A,4-D$9AFH6#$%:,1=A7'"*!:&B)81"C%!#5&6777;+8*E:
@r4273
AGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGC
+
C%$8,D:,:C>0?6)%=$)=?),;96)$8>&4@<'2H07@#"54%,;CAG'(G5<</A?(B0E
@r4274
GGANCGNCANGTCNTNNTTCGTNANCNNCGGGCTGACATCACGGTTCA
+
(*(#$&#)"'#(*##)#%'##*&%(%#"*%+()*&$%*)#+((#$'(#
@r4275
CGATGATGTCAGCGCAGTCAAATGCCACCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCNGTTGCAGACTGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTC
+
73E1/A02;/=AB?AFHAG*B,95'$6<'4!D7B,.8/>!H-H@4#5@=B@D<@?0.C+/:C(609H"C78$$H"0(12!B%H),E4C#,='FG'#/9@A3((:,8*:+!/AGCD;$G.8A*<E$%;H,EG!<B*7'5<$5A"7?<+%8HA&G<#!:')'<
@r4276
GTAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCAT
+
#!!++())&&*#"&"%))&+"')&!'#"&+&+'(#)#!###!((+*(+$')%+$$#+!%*$+%*#"%*&#
@r4277
CCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGNTGCAGG
+
@G;;;:A$"/*?(=@@/:EFCE=.,B3A>1(>.(#&<,H#GB.H(>+;,3@/
@r4278
TTNGTGAAACGCATCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATTGTCGGCTCAACGTGGG
+
D5)6+13G(923/G()8@1..5=:(##E?(;73%%9?6*2F=@9H-7A-$)8;(G<,B-B=+,#7A"4=G12E-!;C@H,;B9'E:##2:DD6GC1/9#&?@/C2E
@r4279
TACATTTCAGGGAGNTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAA
+
#"*++#&)(#"*'%&!&)++%%+")!')#!&(*"%'$""!*!'##!)!&$*&"++#)("'!*&$#*)'*$&"+&
@r4280
AATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCA
+
F'12,.B9F/"?<*!9!,;80:?;9:*2??=9<76AE(:).G/=A2>?+4B><@9FB6%C&??E<1.!&(?89=$0-8E=@GEDB/?17&.1!E5
@r4281
CNCGNTGGACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCNATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTNCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACNTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGG
+
(#&$$('#%+###$+*"()$!")$+%+&"%&)&+$)'#!'*$$"+"*$#+)*"$(*+)+)*!*)$"##(&#*$&*))*"*&!'('#(&$'#'+'++('$*+++*%#'&$#&'")!+*!+%+)!&+'''$+$*#%%+(&)$#!%$*%+&%##!*"'%#&%%!$&$*$+''#%&#$+)+$(**&&$&"*)$$!)!#""$"%')+$+#+(%)(&%&"$+)'!)&$&%%)''($#!%*'&#&*%(*'#"#)##("(+'*('+)'"#)&"'"!"$*"#''$&)+"*
@r4282
AATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACG
+
1!'#5%9B"-CC,?933+GH!96;*>%C&<%=2#<<H=1<C8
@r4283
NGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGNCATGGTAAGAGTTTGCCGAGGATGACTGCTGCT
+
!?E+2<E:%!C41*GD,F9$A;6FCB*;&:F;<"<!F5-.9/9':21-<C/CA'>-*<@5.,./H4F)
@r4284
TCANAGACACGNAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGCGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGANGTATCCAGAATCACGCTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCNNCAGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCNGCCACACGGAGCGCCNGTTCTTCTTTCG
+
&#)!%(&)+*()*"$!%+%!#'%!%#(#*$($*$#)&$#$)**!$(#'"'*&+$)$(*+#*#!*#%))%#!&(('$)"(!$&(!&'#'$#('#$'#&'#$#!)*!%#!(%#$%#'))++%%+'&$"&#!"+%'))"&#!+$%%('$))*"%()$*'&$*"*!#%()"))!(")%#+(($)''+!()!))$!"(''&%%%(+#$''!(+*((+*%%&'#)+#*#!**#)+'*"$'($!!()*''#$$%$#)**%'"#*#)$"+!"((#*"%)!+)
@r4285
CAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGTCCATGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATT
+
4<A#@D,*1&)8#C>-9(78'>!872<51@%)5/+9!:$6?('G:#0D1D+%0-B4E?G;4,@4?#7A>"C77FG,;((7;@-.;GD(61@&/)"*?5;C%:FD40:7H=3742<,A@.8=?6G1400;5-G:*=)+'DA@*,89+:#
@r4286
ATGTTGTATTGATTAANTNAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTCTCTNCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTC
+
;147GB;)300%?1:,F'H?7E7B?2&:#$D,1?,=$<(&;DC'>%*74D5,(BA$,.=@A%;6&4%=8;D)G?C74:#$<#:#5(/'*?""BC-?4),*$/&$0(&")@*G&#)A8<,'G83G"C/$
@r4287
TCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCACAGATAAAACACGCNGGAGGGGTCATCCGGCGTACATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGC
+
-4=!'D6/:5!'!;?,H%%33B-)(4GG81$(4C1((%H3&=>(>6F9-;)$!73FE>0=+$'E&;";-9):"*>>0,C;6?==?7C5+18<>%3AHB5,&7A/2!3::+#"E&)5!=/;C7*GFDB1-@)"'"7G'?@?8D21$1702D543$BEC2%$'CB&=H#"2&</D5*8HF7B06+"B+/H@$0CH?+&G?>7H..=H88A&8#7HF>!%!A
@r4288
NCCTGCTGACGCTTCAGGCANAACTCCGGACNCTGGAGAAGCATGCCGGAG
+
!+')$))!!#$$'&&(+"#!!#$#%%&("*##&"($#)"!&$)+%(#&((*
@r4289
NNGNGCCNGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGNTAATCATTCAAACTATTTAGTCTGTGACAGAGCC
+
#!##)'$'+'***###''!'(#('!$%+('$)'&&$!)'$(%#+%$!($&(#()!*(!(%#+%&'+!#&($(!#*%'")&'&&&&#('"))!)(
@r4290
CCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACC
+
1><?+0))5%.7A+=>)&%4C4)?CC9+FC;A>*G5950@D2C0>#CD742?$3%;9<
@r4291
CGACCGGAGCCTATCCAGTCGCAGTTCCCNCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTNTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTACCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATNTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCNTGGAGTAGCTCATCTGGGCGTAATTCCG
+
*=@)#HA)1.>/2,7-C=36*A55'*H;3"B!@9;!#<&C=*>G-%=C$!!>;)-F3A9,+"0=.345.A**H2'4H/.#*:044:0$75E,&:"530$EBE*H/C7%8AF@$43AC/$5A%(/"36%&/9FB3,)'"CGA91-8(1>4,*=H?40+7/$0G!C$1"7+(H<%=GF502;)(C,0#(+(*0>1G?7B+*:@4B!H*",?6/(%":#7(C3'B<$FBA!-74B)
@r4292
ATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGNACATNATCTTCAGGCTC
+
')+*"*")+(&#)%!#!"%)')&*%#&!)!*%+#$*&%""("&*%(+*$'%%"!&%)'&&&)'()$)')%*+&"(
@r4293
GATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGT
+
*BED'EB8+8/;DEA!FB)CB*C@,>%+.(FD#22-+A.1>H@6$7<)>GC4A*&+
@r4294
TTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACT
+
54,)4H,:D1+H;8=(0&2<E8#?A54$,A,/!7;;1A<6H*C*':%;EG<A3FH-;9>)B1*F(;"B&$8
@r4295
TCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGA
+
6$3A@<4&8D,@51(%?/.;"4.B=%?=.G9$G&G5/"2.*C8G2$
@r4296
CGCTGAAAAAGCCGAAACAGNCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGNAAGACAGTGCTCATGCTGCCCTGCT
+
#6$"G4//D0&CD"''#F,<A8$:G.;"1'@'"04/$&3G,<8%6&A%.F,'<>"7C<FDG2%,A*(#H9(+?9%H+>/
@r4297
GACANTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAA
+
1;-13E,=G!*#/8>/$;(87+)(>E.7-(,?#+)0!1G==<;C48;&/F*(
@r4298
ATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGC
+
'3G&1A"8<:9C+%@7=29)0(<<E+%%+1%9DGD!%E5H0&.&2%F3>5(
@r4299
AATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATAGCCGATGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAG
+
F'C)&3=0&!%!<,<E%(4(GC3D<DE!@1;?>0+@CD*<5EA840'3/DC#0E"5H*D9;<"+BA&$,,1-@,8F-0%108<G!;-7AD&',(7/)=7;6H<,@,A!5EG&H%#/>5(.814:,
@r4300
GANNCTGGNANGTTGGTTTCTGACGTTTTCGNCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGACTACTCNGCGGCTGCGGCACTTTTT
+
#&")('"""#"$*&+&#!$+(!*%%(+"!%$##)!*"+!%%%!"*(***()'+""(#((!%'*)$%&%'$&+$*$*)$###&)*%!$$#)
@r4301
NAGCCAGANAACGACCTTNCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAA
+
%+'#'!&*!(&!%$$'&%!&"%%*"&()&'!&'"%$$+!$$(!+$+*#(&+%%)&#+!%
@r4302
ANCAGCCCCGACGTNGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATNCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGNCTTAACCAGTGTGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGC
+
#+"+&$!%&()&'!"%("'*!%)#+""%%+)'&$$%*&$##!#'&!"!")+&#*+(*&+"(+'%+!)(#(!+)"#(#&*#)#(!'!(*&!)%)'*"'($'#!(%"%)%'$*'$'*#&)&"&'$&$%)&"*%"#&*"(&"'+$)#'%#')#+&#$)%$+&"##&"$&(+$++!*'+!#*$+)(!!+('+!))
@r4303
AAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAG
+
1.D*G,$656=$@16*+?+3&5G"F%(,$E==6@16%):C"%?
@r4304
NTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTAACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCT
+
#.4),<G>11(@(0:C(F+:2+A0#3+@"#G1$&!;+CE9(1*->/FC?+G#6+::6,D19,-%?'C)GFC#34672%?4<1%4CEGE$3,70C*!="FD,;4>E55>39"C>%%9.@D;B'2:=1@>'A2D.1>E375)$6,>+:<!@->.0E-&
@r4305
ANCANACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGATTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCNTCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCA
+
$"*(+$&"(%$(!')%+'!+%$%!)$&)!'''!)+($+&!$+()$"!&%##'%*'))&+)"!**''&+##!!#*%(%$(!"$$(+#&)!!%%"$+#%**#%)"%'((%"$!+$##**#&!*"&!$&"(!&%&&$#')!)!''&#&%**$)+!!#("*"!%!++)")$#!&%%(#'*'#'!!!)!'%*!(#+#''+$)%*%!%+"'
@r4306
AACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCAC
+
:.GE/-EG.%*;:,,.7%49./:E8E/."<6!?5?1-E.*E3@%<$*'15<(2:%H!)$*5"7H#/
@r4307
GGGTCAGCCAGNAGCATCAGCGGTGCTGACTGAATCATGGNGAAATCACGCGCCGGATCNCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATNCNTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCTTCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCC
+
D7>)+===7*F41%7:&'F$8"/2D/*+B7%GE!@8'4F,?.4+"E$$(<>$&=3H&FH1:-D#>>-<)E;D>"479'0307"730-F9/@/*1.9F2+4C:7CD>H/6A$',+-%0D#!39'3;2C=EG5%=2%FF-E*2=95E(!*>+,GGA*;2'#6D+/46F,0<7.79#')B@902@:&");&9$.C//%G6?'1)1$/#674%#)80-53.
@r4308
GGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACNGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGA
+
3B!!E2B:(7@EA3*&/;E;/HC1E!-E+'>B334:?C;$E8.H57)813);?3=(,A,5$>#;,E0=#3G/%7*)90&*"<D:)G..2?1/("'+'F@=)8-B*2-,%C3!"/D*@<@4$2.@H
@r4309
AGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCA
+
279;:=4+%+/C3A4F!>/9>B9<<'FG=1224=<#B':B(H
@r4310
ACGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGC
+
!.1@HF!46?#"#D(4<.,H!69?5C+-2*42%H3*?1#9$B5
@r4311
GCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCC
+
,::3D%/!BA<0@-49#AE=5D?B."A64F?>HC-*.F=>6@%F/&D
@r4312
GCTTNGTAGTAAGCNCANCNNANTNGCAANGTTANTTCCCCTGCGTGAATATCTCCGGNGAGCCGGAGGCTATTTCCGTATGTCGCCGAAAGACTGGCTGCAGGCAGAAATGGAGGGTGAGATTGTGGCGCTGGTCCAGAGCCACCCCGG
+
%%((##'#)&)!*%&(#('$#&#%'&(((#$!**!+&!')))(+"$*$")+(!")%%+*!"(##*#!&(%+*'+'*"('))"&"+&!&$('%*#'+(#+')'*%+$"+)#"#+&+'!+*"!+$("+*+(+))&$&*"&$)(+(('+#%%(
@r4313
CGTNTTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCA
+
E8?,>*+B514$?C+0#G:'=C-/?:'A6/;1'H"7/9!4>1C2='F*+.+F:90!2!/>?">B?%+D%A3;=<?).6<6*4H,-4-1!<.#B6H0,*:E
@r4314
TGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGTACGAGATGCGGTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCNGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGGAGACGCAAAAACAGCGGCGGCGGGGAGTGC
+
%D#@(&"=??E?=)E(,*<1/'9:B#9#&4<5%<'8#1G12488E&"+%,#&*BB5?>CC*/$2FE3,$,#*=EEH).<C,%6C!$:F@'--8#0"<C()-3>?4#H">01&''8A'#E?/2H.=(0'8(%@)4</9@7/B'%1G.6<A>9/49-+E8/@11'5>H5%8'*4$1A'-FC7&9-523.1H#.28$(<7*7!?7B,='43EC+$<7$@A,+58F9*32!9'*A4'1'=G".$@$<+/=E9&1=!8!":.7%1'DE.E6G:B82A&/+!':-!3A)/0:A!
@r4315
GCTCTGGTNGTCATACACTGAAATCATCGATGTGAAANAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTANTTATCATCTGCGCGGGCG
+
53B6CF(H*&"G?'G;9@9)'/5+)9*H'6,=D)&,<06AHF5DD%"/:*$"#,?09%))#:8!F#,/@3+8'65DCD;F;BF=G;%/:/C/<7+=+H@%=H1$+B/CCF<B%*05/$);D7%3/&=-*:(G
@r4316
CCGGATGTGTTCTGCCATGNGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCNGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCAC
+
-=0450$:G8+4E"E*C+E&;*"E))%G(9!$3"/B,,(?B;=$GA090A@=*(,7,&A'41<$@<,A*?26+!0#$'@!HFG!(.@)'/D:"".0)!7$HCE9!G8>/>G<&E&13A81<+40=5:1H-%C9$>%$;4)67F6''#F!5%@,"8?2.3!6$?'>,.:,(<+-
@r4317
CGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACANTAATTGCATG
+
8:+6F:5A4,-F57=D!4$#/6F3$:*.#'59GE#!9$-7!+!@4!.@%#@>-%'9+H:/%&6%9"G&
@r4318
CAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGANCGATGGCCTCTTCCA
+
;:(@&(AA*EH73FB3CC?8!=++G+:#2*>-6(6HHD3C;>;&@$.1-:.%*1)(+9'D8$9%B#9H=;+G2D?;:9;7F#124H8;453H#*
@r4319
GGTAACTTTGTAATCTCGCTAAGTTGAGAATCACCATTGGTTTTGCCA
+
1$$B3@8.?E81%".47&HD@>C&!#-:+8=$66.*6-**-&@5&81G
@r4320
GTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATANCTTGTGTGCAAATTGCATNAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGGGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCA
+
.B&39@6:6?2;0-@0%5=*FG1G'5:+&85+=<=&<,4"==/7G,0BC!%B'$324F/8#:A#<3F=1#GC-G)B&;%@-F"=3-B)4GD?,!91BE'3&,@820,386H<#9"4&"/=(20'H4-1%59@;!?!1;'A++.;8,;'B#D9H%G;>$<(C*525+!3$0BB4AH(%!3)1*2=
@r4321
AAAAATGCCTAGTAGTTTNNAAACNNTGACNCGCATNTGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACAGGGCGAGTTTTGACGAGATCATGCCGGAGNTCATCGAAAT
+
')"&"'%'(%))(#!#*&$$&&%#&)$'')%'*)#'$+%)#%'+%&&*$*%$!'%"&&&'+##&$%%(%$&!'&%$#&%$'!+$$'&+%&%"&$$)'+)")%&&#$"*)#!+##'"#$*"+++"$(#%
@r4322
TTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGNATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAAC
+
'5D/'0/@B2-:@"-(%0%#1-&@B&&7-#BB;B-A?D!&HD$$2(&4:26+2?%3$3)#!=57-F/#*F3+)#0"G08/87?&"9:B@*#"H>!=?;;@&):@D70(F'AF%0>>:646+77E*0B8-),@>'F@!C)B=+B(1;5<A(E+
@r4323
CANTTGAAGATCAAGCAGATAAATATATTTTTTGNGTTATGNAGCTGACAG
+
:&(BC4*/,=85C"4(H#>,1.055+D@7</&,)FH/6G2F;22C+H#0(G
@r4324
CTGGTTAAACGTCAGCCCGGCCGCCTGCNCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGANAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCANCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCNACGGACTTTGCCCGCCTNCAAGCTGCGTGGC
+
D-9&B*+!*<1@,E26H9F*.A'??BE=;B).#HC$-E&GFB>'-GC(9F2$,0H>&*5;'3'8@=1#4+CB&E14B2,*F4&'7E71=>;+.>/(17/,<C*<8!=C,53/,D((D61/)=D&50*70<#B.*6$0A"EE=;/*):9?%22;62254#6043,F0<.%>$?86!!3B5'29/>!(D(+E).H5)9B!&H+3?04/?&/@!FDD)+?*2'C75**(=,=#G%#H-;21D';:<"@;#:D8":3:'6?(HG(+5):B*/:(01%FFE>!C66?'5:<>&BA9#<>3;2!1$=:")&$7B'$;#
@r4325
NCGGGTGAAGCTGCNCCAGTTCTGCTCACTGCCGGTCAGCNTCGCCGCCATATTCTGTGCAAT
+
#>D=-#G;$4E8<E#/@9:$E?%?!%3D06*%%51#E*4B8@'D@*(!40,"G86#,>G%(/B
@r4326
CTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTCCTGTATTTGTCATAATGACTCCTGTTGATAGNTNCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCNGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGC
+
%+%(*%(&%))"*('"!#&!''"++#(#%())&$*!(#"+&$+!%"&&$+)(!$*&!&%+!+'#!%(&##()%)+)'&&##!(#&&($#!(+")#%%$+'($!&"&&&'%!#$!!!)&()''#$+&&!&!$'(%+)%!*#($!%&$"'))'()*''")*%'%*#&$$&))
@r4327
GATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATNTAGTCGCTGCCCATCGCATTCNTGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGA
+
$.&)%33.BG;H!6)F1%6B*=)4-DE&HB'!5H*332C()237D3)'>E;-C('5<'88;9.C=H6)64>#:!.,&&G@$E#86G352E9'??G/5,4-%C*6,#5*DHG1!,DB;0>AH?EADA1)"+B#/B(C'1D
@r4328
CCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGC
+
H9B&##C')&.$$3(D@;#C%4"<G2$));9=!&..+=(5"E>>
@r4329
TCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACT
+
C6G;5>G5:+#87<'#&@CH>=:?7?G,%>@6C7$%=)/$BB*#@8E.,<3G@F!H
@r4330
GTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAANGGTTCGCGGCGGCATTCATCCATCCATT
+
'31A-!<E#&>14?(@=E!7*!-F:<,'6.;H0B2(,#6!("56)F4@E8H2$'F/@($"+=H!&&'>5D##/@&9?=D4.$7'
@r4331
ACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACNACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCCTCATGGCACAGAGAAAAT
+
%=5%H9))(B7E<%-4,&:*;E@A;-%'&?6*),*EG$G'4(":33<,9D%A)DA'63;=EC8@;.H==HD-(+,,-H'D>-299/D?@8*C9&02C.3$29&!BG8;$B62".'D"=@.*B!??$16<BGE4>AA(E-"!>+)?5D9%/1-3$/(.A0<
@r4332
TACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGG
+
>3A:C?681G"E27D:;08:;G64>9@(F'H<B/#+'=(5?
@r4333
GCTGGGNGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTANCTGGTTGCCGA
+
0#$+,31>>B@B>,1)F.7)+"!A4>C/&'F%-<*2#/E4.E@(#29B557G%:A"%%B:5=
@r4334
GAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTANGNGTACCGCCTGCTCTC
+
.*6:!'#>#+EED2D&'-,(*E/3;4&7D15:$$FB6:-#+H,5C>=F&//@,?)(>B+5G+H3:(CBAF$0:B8!?C@66<<'3##
@r4335
NTTGATNATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATC
+
!)')*'!&()(+'%%(%!%&'*#)#&')&+%#+)"*#%&'#)$'**$'##"*%"%&'$&+%##'($'*+)
@r4336
NGCNCTGNGGTACTGACGGATTCATCGTTGGGGTCNGTTATAAATTCTGATTAGCCAGGTAACA
+
#"$#&)($#+%"!!%+"$!$)$#"$'*!()*")!!)(!)#*&))$#%'%'(')'+!*(%%*$%*
@r4337
TTCAGGAACGCAACCGCAGCTTAGACCAAAACAGNANGCTATGGGCCTGCTT
+
($)*'('+)"+'#$#+*!!!#%&+!+$+'!())")#*!$&"+)(##+***%%
@r4338
TTGCAGGGTGGCCTGTTGCTNGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACNTGACGGATGGAAACGCCTTNTCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACAGTTATGTCTATCCAGACTAAATTCACTATCGCCACTTTTNTTGGCGATGAAAAGATATTTCGTGAAGC
+
0EF-'"3!="!'H9@H'$12E.$35*(-:?C>1%4.;*5<$-!F:/!49$#;4->;DA+94#G6A2#'<%/9?<$+!FGE09':1/:A.->0H9(C'"D&$C''$@4HH!'>2$1&2@8<C7<//"HGAF#110$;%)>H);&)'@8D#6159"E@*>E0>?GDD9%*<%;1B3H:4.B,<6'G.+&G/F;5,,+DD$;/
@r4339
CTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGNAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAATGCT
+
@GE)%E4241<)1D(A02HB/2)D41G6-!EHH<C/"()&2<*.B="HB!.;8@A17%=1*@G?%!;0G!'1+7&*H;0/FGB-@EE@48(
@r4340
GGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGA
+
3.'=7$:0-4=/?4(+-%;8F##;EG2%;/82/&<6&H8@@4/:50%03A1+/:'F27G>G6(&+
@r4341
GGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAAT
+
HE(A.BFC*6(9559+".1;.6A5:#7B@6B>=:=(??"@@.4:=.'5AG3D@'
@r4342
GCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCAT
+
)?;!#?8.E*8!@=0G5!-%)'H4;=986A4D,1&+/*:<A6&!7$$A
@r4343
TTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCACAAAGACGATGGGTCGCTGATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATC
+
A6#0BA43((2E+-!25%,H/6/*>>-;3"D0FFDA11#@*!$HA!=9>G;F)G/-<1BC6>7'0<(+<*8,B76D5*?F>&)0&>+4%BH-.F?C8::F?=)?H'H4D2/3#D'8@=<3$?=5*C
@r4344
ACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAAT
+
G3F*;4H)H2CF7DC3DH/<E'@.7(3G)&)@HDA/D9CH.))%7A26$+H&1+48B#$=!3D*E)$"D69C3FF?18"797A+A';9?6,E8$7697:(48+!F
@r4345
NGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCNCCGTCGCTGNCACCACGTCAGTAACGTCAGCNTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATNNAGTGCATCACGCATGACGGTNATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGNCATNAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCAGAACCTGCACGGACAGGCC
+
%+-+AA81&.#&&-5@:/:6BB.A&@@E3#(D-.6+&D3#"6B%$;!62569.%.(HB?+H9H/C9:*;>,";AGC2<H.=!"*E@@658'$6.&*4B.6)6*A'#&!D?*?1C&.C:/6G**$6-B-<%8:1@7-0,5/HH#=G/D2HAB.?57$DB-H=(<+).:+/->4+>H2#)9/3".?F'9)A%02D-4*-A!"2?4.:B#:H64!%,89'?'G!&56(;,F175A:-C'7+E<+9@E5(<(.$>/?##?)-H/0D.-7BC>0,*?*6"=7$EH)D5H<<%3-HD@&=
@r4346
CTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGAC
+
B*F.G,A5FF?B0'+-,%>2)6-EGC2<35+3*1>!)>9'E0#.!-=#A9<#-:1073+%D,+""3,$/@1;=<+7*E>,B4<
@r4347
TGTTGCTCAGTTGCGGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCNGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCT
+
&2A0AH<@'</9*C)..<'12F@,+?G)E5!(6@/+,>'B+C#2.F.!,),:(6;.4'B#F)C%";B3)3=F1*0'(6H80&(),9)!*H/=&6%?/%3'G$7D/'&.BHB4*@93473'$(.:$@%4>'#A7;+:G!E#%:&7CA(<<3G;C04<8;6@:B&<>F/:)@=F=B
@r4348
TCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCTACCGTGCCGTTCG
+
/"/$'$#9!B=?A"5:1+;@#%0<BB005#6#-?:"5D!2.D*>F3C&F87--)F')
@r4349
TGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGANGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTANGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGT
+
>>/8-B4GDA'9"FE6H"D<=*0$E0;+(>$>=).+*F:/+#%>(A47.D;?GG5FF&!0$@4581##'.3*=+D&&D):4'%B>45#%<+;,90&7!5/8G7CD8@D!*<'@1D>=H$=E(:*6<&*HE.=$<605+7A496D>:E8530;=A&#46376C!-G"A&$3*(*3%F2$+71*/A+6=2G2>B*#=&=0%)>"2)08<?0=/+3G&*'!!-E"D:BC!D2E/1.?#)F7C#0+%,5=#84+$?%C@8H/1*!!60>28>H@./&8*85;F5G-5
@r4350
CCGCACCTGANGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCT
+
4>:&5*(H6!")(5(*!',#(,5@C&A2$=$,*+#<2')&!)"AH3/G0(&;?@=#@95!H
@r4351
NGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGAC
+
&0H53)6B1BB-:-@2=5,&78A+!-ECF)F=(!7??$F<7B1'!8
@r4352
CATCTNTCGTCNTGNNCTCNTCCNNAGAGNAANANTGGCCCCGAAGGGCCATG
+
**')&"!("#%!*%!!%(&!)%%!"*&#%"$&!$"((%%+%#$*+&&)%)!+$
@r4353
CAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTA
+
0;6F:D*%9B-:+(,HA"2!EE=H-?D26$)&#%-1?.37#:3<".<&=2#4
@r4354
CTTCGTGTGAAAACGGGGGCTGAAGCCANCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGTCGCAGTTACATGAGACTTTGCCTGATGGC
+
#+(!'*&&#'(**#"%&%!($&!*#$!"&***&("''!*#*&!+(%))#+"'$!"*+'+&%+$!$#&&'!$+(')!*)!!"!(+'(&'#"+*#)&)(#!(+"*("**!*!!!*%*"$&)'%"%+"&*+)*&$)+)$++&!')"'#!"#''+$(!))))!(%"
@r4355
NTNGAGCCACCTGAGAGTGTGACCTTTCACATCTGGACAGCGTCCAGCCCGTTCACCACCTGGGTGCAGATTGTCANAGACTGGATGAAAACGAAAGGGGATA
+
'#'+#((#+(&%*)&'")!*&"&"(+"%+%"!#%'('+#+)*+%#%!!)&'#%(%**#("*%*!$(#%!+!%!#+!)%")$$"$"(&!#&''%"*')())++$
@r4356
GACGCCAGAAAATTTAGGGAAAATAGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATGGATCATANCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAAC
+
E%=B@$,('(>B,B-43+D:1#4)0*!+@C6D?&;7?(>@?H2%<A(?!3;F-5B9=B$4$?/2:4GE+6-B@8*<*+9BC;<H?8%-)D=:57EH3/)3180;,:++B<>A!@02"<6.0&'?=<0#0,182BD=4(':#3&1F@#0%&4'&0%F(ED)!C0?B9.@BE.3D,16"?55;=7>B3+'5+2,8//;E:>>D/A6-7':0"':B2"29>$C+E@
@r4357
TGAANTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGAT
+
/1+03,4'?)%&/B5=?;G$B("C2%6?@71E.A45=:)20F)16G?GE)&GA?;7=;$&)"0%@6)%&6&#+$A/<H'(&"'(5@.D@/!98++C&:/D,$1.@+5771,A@2G
@r4358
CATCACCCCNACACTGTCCGTCAGCTCATAACGGTACTTCACGTTNATCCCTTTCAGATGACTCACACCGGTATCC
+
6A$5$'98C687EB<"=BC=A.;*42BG??<F9@54:0%-4$8*&"<&*-7.??@-),'#D;8D"F52@3C4:*E.
@r4359
AAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACC
+
4H9"=*E(<&D?'<<A<7-'H094H>)G6%*.G85;%-*$,H7!6%3E/>,!,5=4'7F7'*AE,G6&<'C$C(5B/7=+F(!:D9"26*+73@F5-!;,.0-+%4=$*(,@.*1=9&6A9;7)D-*DF*;E'A7((*"%8"<:/<$$7<8#&F#'<"G4-
@r4360
NCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATNCTCTAGGCGAATCCTNTGACCAG
+
!E*@!*)3A(E%+(.H&,B=='5G<C2D#$/30?D$.+*#.*C7=7&@.@"+G!8+"8@9",%3=-"-.#<'&=&B+5:B>+C!26;#0;/831669/
@r4361
AGAATTTGTACCACGTCCCACCGACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAANCAGCCCTCCTCATATAAAAAGTATTCGTTCACTTC
+
:%%55$,E<A9>6!8#4,@CB.7D)D#1;/'2,."83,,$%0&0E?%/9."@+HF#,+:E4>34?C';2DE")*@+*>@.&-B60F21/,"3A;1H!+,B*.=&,.$CH8)8>>;568*&46?0&B))0&8G'(0:-0#9C;0$)D&9;)>B+2.#E@&86(>D1/H-=A04*229%54""G&)50G:?312;=#$6G7(
@r4362
GCTGNGGNCNCTNNNTGTCAGTAATTGCCGCNTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCNATGACAGCCAGACGATNATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACNGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGNCAGCCTTATGCTCGACCTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGANGG
+
##$#!!#!"()'!"+!')+#+%'$'"(%%'#)&#$*"++$+*%'!!'#+!("*#*%)$+*(%#('!))'!+'#"**%)&(''!"*&%)&'%("##)+"!('"**!(*!+)!%#%#*'++%)()&(&"&$!!(#&((*"##)"'!!+*(+(*"&('"*'(+($'&&!&*'#""*%&$$$+&'((#(()&)+)*)*&&%$&%$&%*'("""&&$#+))+(")!&)"#+#)#"()"&'&(*!)#&)#'$))()"*'*+%#!&()"$%')#%&"#)(*!+&#$"'!++&$$!$#!+("(+*($&++"$'('*
@r4363
NCANCAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGC
+
"'*"#++$!*%!$"#"&(!"#%!))"#%%))+%)#*&&%"$&!(
@r4364
TGGTCNNCTCCANAGNCGGTCAGNNGGNNGGGCNGACGTTCAACCAGACCAGCGAGTCA
+
&!*#%("!%%&#!*'$*&)$$)(%"**$&('%)%)")**!+$)"*++&!(%!%+&)*#(
@r4365
AAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGT
+
8.?2,!$$/H!!@D-88*B@>39D5'89B,G,-CEC003+B,G0;?"0=G>:F;E$?*A#.":!76?/66<!.!;6"0,<ECDC9'=7CCAF#:&7'9G<GE%?C?>23@&F=51#236/F,/C
@r4366
NGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATCNGCCGGAGATACCAGCTNCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGNGGTTT
+
%22!%H&+,G!24>;<&38@/8EB<?$>E6='H/A#)'5&.<B/&";@1$7C<6,C1*B23C2/?*6</CED)B>'.5A&4,8CE#$$!E4%E.*F.B(?&&,$$@:&.",&2/*A$AD;B
@r4367
AACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTCGCTGAACGTGTTGGCATGGATTCTGTCGACCCACAGGAACTGATCACNACTCTTCGCCAGACGGNATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGA
+
AE1=/>.(2G/6DC8$<:-+8#&EB5?$.#@4/23.<H$5##+.8E+;9*>8!A6E:(D>=@G%&.29C":/093816G:*D'%6E69).?B4!B8+8G%+9)4:A=0G8&%#=:6"?$"9G->/*<7!7*0-71EA<@@8E%A@!$G62H5=#&D'=(//2F;3E35E1G.(0=<%;EC+::25(40!4;<(.85**,&7BC"=</88B%0<38$D:*,9(;;BH51;-G,AD/<5/.-(G-031H,>A<07/*>9H*
@r4368
CCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTANAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAAGGTTCTCCGCACCACGATCAACCAAATCGCCCACCGNGATAAGCAGGTCTTTTTTGTTNTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGNGTAGCATCCGTGCAGATCGCCAACTACCCAAA
+
@%.*"46A38,0>9"C!G4AB$:8H(/H3&E%/>2GE2D.#A3-=8F7+$A%.E+:2:?='14"/AC*.G%C;(&1'9*.@-%"908(;BE#<"441A,$E@)"DA"-7?EC+(4<#1,4//H?<>"2)B>*@>+818<D#?*C.C99E%-;3/+6!*BH*/<14-<8<;+%<9('$E7!+.F>*5A8D98+9)')3(>:+'B#CEF2E:7D>=A<C7%,
@r4369
TGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTA
+
5&9D;""A.<DG@021A49/=<;?@$65FAD1/:6%8B.BGF5F&@9<<@8'=?B+5H0@$,)2-#&$#EE2
@r4370
CNNGAANNNTANNCCCTTNANNNCCTTCGGGGTGTCCCATCGCGCCNGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCG
+
*(#)))!$##&&""'#!%$'*!%+#"(('%&&%*!+(#%$)$"'''"'$(!+!$#!#!+!!'""#+'#%!"!''$%$))!$+$'#*+)*"('+!!+#("('!!#!"!
@r4371
ATGAGNNGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGNGTGACGGTGGTGTTCCG
+
"%*)"&"$'$+)&($$$('()(%&()*"!"$&%+)$*$"*)(+"*$$!#!&$%)(!+*+&"$$%!!$!
@r4372
GAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACNTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTNTATCGGGCGGAATGG
+
(>>EH1-'5BH<7#31)%1'H+<BB0-<8F%<CH6C@7!;:EG3;7/71"0C(B0;<D4?7B;A:@<==HGG$>*;6H4A/20C97,CAE=<,AC9<%7H
@r4373
TCCATGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTCAAAGCTATTCAGGATTTAGTAGTATNGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCAC
+
<H.@.1E(/)*3BA,(.D860;)&#FC,*95H/-$&.)(EC/6B%1;=9D7+84CEH:,G-7D=;%#629#'+5*;5-2B8=3)5)=#%#/5#?*5*)A!C3@&'8C3)H+(.0A.7C21"2:G(;,5'FB?"1!'$>D7A:<.<,61766'-)&%*D54)F95F636
@r4374
ACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCNTGAAGATGGGGATCNT
+
,>C$%GF)7!%$@:,;;:=B3%A46*">+3>G8/!!9E+01%;=8:/G.8E(D474"!9&!-,7057>A,">2$>6".D1A
@r4375
GTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCANACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGA
+
DFF'$;;$'(F>%-2GD.!;8.-0>F1G@%2=.)6/7$A@>!@,,@1-$(?*9-,C&@B?";9=)71.>;<>;,828>)15H2B?!+%#-8-#(.+4H$9
@r4376
AAAANTATTATCACGAGTACGGTGGAAACGATACTGGCCCTCTCTGTACAAAACATATAGAT
+
'+;)A(.57;&*E2%/.-11@F,D9)H?CC<.&-DG@76+*,'*-,E5AG)G$88?B=H3+&
@r4377
NACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTT
+
'A83(56B!9&'($#-&CB'%$#1-&@8>=>A-:=0<0<D7#.D0G,-)G
@r4378
ACCGGATAAATCCCGGACTCCATCCACGCATCCAGCTCTGNATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACG
+
@==@.0C#8)@F/BA;<0.?9B+?(*"",24*.7=A%'H,E=>8@:2<%:89,3-9<<(@#;:4GC8H-E<&*(5C%'H=)CC#,)48E8)HG0&25-EDE,-5;(6-"*(#$34HD(<=%.F9C*@2:,G<-.!62H.E??(3
@r4379
NTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGACGATTCAGTTAAATATGANGGTAATTTCTTTTGTNCAANTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCANTGTCATTTTCTTGCAATGTAAGAT
+
"?$/H%C:5%2F=H/:,6)?*=9!@)&2+%.F,<<7-"BD>?;E>-./!@)=%!)5C%;/2E/F,/D!#?7<19@?E%E)1G03B&(66B>9<8,-,8'>F+'A.;6+?/7';,''C1G0#3*!27G/44B(GH!D:DDBF8+6,>75<3@F:$&F;.G)!;#.$
@r4380
ATAGTGCGGGTGTTGAATGTTTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGAC
+
69C("A."<1=(;*,?>"-D$,3B%&&89?&D2D;CB.,'*-HD4.D3H/3(8%G%1)&D#D%(-."70:(%%G4/>8CA8(GCDD0*04A6H5
@r4381
ACCGCCATCGGGATTTTCANCACATCAATGGGGTAACGGTTTNTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCNCGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGNGGCGNGAAAGGACAACCCGCGCATTAC
+
+'*)'*&)$+%$()+(&&(!&#()')$)))+&#*!))#"$'%('!$&$!&'$!#$#%"&+&$%*#*!*#)*%)+$+'%***$!"!'"%*!&!%#'*$))(+)'!*$)#"%*&&#++%#"''"'(("&(!&+!)%*%")("$"!$&"$&%+!%++$%%)&'%+$"*'(*&"**+%"&*"+*!&$%""&*"#%#"%"+!$%&"*)!(("*$%!&
@r4382
AACGGTCAGATTGATGTATGAGCAGGGTCACCGCGATTATCGCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGNCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGAGGATAATGC
+
%GA)D*?%';HH15G:F@=(3%(,&F(A=3!5(!!!F-61500#,C$??.2DC&=.5#F)%-,/9C4(0;358*%'H+G;&AC&>7<=(1,C)+2/**5&!58?$9(.-@&46%%5)$>,"#7>78$!H?")2%@(*"8'A%/6G<2->.%4=0"-945H-:=E"BE?/#$2!HG5+F!,&4-'0@&"$%@!'A>=2-A;53%&,3-?%G$,18=2(%!1)48-,<'/8)?+.2H*2*?3684>20DF=(?0#"9"(*$@'GB!B%/(@>DC775A(;(:&GC-/B1"0@"3B+@.3GE'*6F0'*/."0H1/?9%@;HA-,84A4?"!:+:7*<E+*6D8'$(!25'<9?C2GG!F@
@r4383
TCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGAC
+
"'4)?;8H1=32/4"9C+@C;>5<">B4==C*8("FC#*>@G>A:/1D*BFD9F::&,7.)G57)';"E#=,5
@r4384
CCTACCTTTNACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAG
+
*4D&=H;#E#7H2ED85)GA++:!7G0'@1"3G2;3)D92$F85C(59)9/
@r4385
TAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCG
+
+!#+%""%+&*+&&&)&)#))#)$#!$)'#'%(&''(&"+'"%$*#")"%'&"+%%+(%&(#&)('(*$%))&)$!%#%$$"!+$))'%"+!#+)*&
@r4386
AAAGGTCTTGAGCAGGGCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCG
+
)7"(9?@A'>97B4.*=B21.6<=8+?1.A.,B7'>"D(B@'$0!0F&#E/9%'@H4(DF;>25?95
@r4387
GAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATNAAAATAACCGCAATTTATTTGGCGGC
+
)(3$=/3=#)G+A$F-#("D*)@$$!-B'=G8<33%#,)6,D5?'0/93;#E.A?.A#1080>FD:))'F+*@/(H6"193!%A7)(.7:$0,E30,0'G2G>-$97?:=4:*:+G'6E9'1@(=(,;D5$&..)&60&1>6-A;6?HHGD8,:!C)36;73=G%6=($G?22>%0)1?46B+3==(8:9"GHD+;"A;7:@1@??=>?>+6<*,%&"%=G@G;$5#BC@78'7DEG>A#&9+ECFC<-<6!1
@r4388
NCCGTCNNNTTNGTNTANCNNGCTAACCTCCTNAGTATCCANGCNTGANCCCNGGACCNTTTCNCNGTACAGAACAGGCAGAACATTGCCCTGNGCAACCATGTTATCCAGTGAGGANAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGA
+
%*"'&($##)$!($'#)&%'!)&'()%'()$))')"(#$%$(*%)%#'"()**&($%"#*$*("*++*%%$$&&"*")!"#*&(#!+$((!#"+''+%'"!"%*!%*+'(!%#$*%!$'!%&)++(#+#+'%!*%&)#)"*))!#!*#"#('*$**""%&%$)!(*)$)!)+!)#!'%!*#(+"%**!'$%!*"$'&'')#++&!%+"'*&#+'*")(&&)!*
@r4389
CCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAGCCGCTCCCCNGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTT
+
2>%0C.;G%E.6;(<GED4-<.!8&;?1CD6;3D.#74(0FA*8"8G@#7C=G<>GF@F2@3%F2$39A)@(=9<&G65.2?,<"7$++3'8*EA-D:??0:/D)/B(-!0%,759-8=#5-#<>A:%*F0&5'?$7..4)76*<%
@r4390
AGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACNCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGAGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCC
+
C4+9>G?44@-$!/HE8A."&29!,)!C=;)@<9.G,5>*G*5H5A.2&;DH+;<<><*H37-:+#=G@50>HDA<6<HA1-B/@")#(()&(:F8B/8E72F9;86.D7!%G79D9>:#?"C?##%'5=)$!;+*B*)1=D=)4:(::>?,F,<%749,:#0B+-@+4!.B,H3<?>:#$/+<!)!79*G*>%7D?730D"=(";+!$C;
@r4391
GNGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACG
+
)!*2>7*><7+-)>?--;E;4(,2G%G*&A&A4$)%".:9:A78/<GA??);FAD"*B>G53%$E(8H"
@r4392
CTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTT
+
39;#F$"D%759--(/A>0C0=C7/++&5#,H-'87BB0C.H3F:*>2F7'59:%1;BC:G+E:(6,3+7+B17&:3F/1:8//7A6#1-/(AC!3G>CF,1B(C@CDH,&&9@)0B5%931.?:((.B=#4:0%6#@(!6&'*1(B(97/D,),-).2978E@49@889!(=)E##(3-1"92GDCF39&4D81<+"A#!
@r4393
TTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCCTCNGTCC
+
:G.!.B3D2?<*A!E?E+FA+4+"-3A0CC)//2.76%A(,-+74-'2E-8:3/,EF1D7,H(-1+5@59A1H%,2A7.=01:9#4)>'!6#5A*<47
@r4394
CGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTT
+
..9/F</4?"D1.0'/C.FBCA-A*+)#::-!+?:"0:4.
@r4395
GCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATC
+
<%82-"37D@8CG$(/=""+E#"-2*4>@EH5##-?10C5<);)=DF@21
@r4396
NANTNCNCANGACAANAACTCGCAANANCCGCTTTCCTACCCAAAT
+
&%$"$$!$&$%%%$'$*)%*')(*("#!+#"(!'&%%%)"$++"(!
@r4397
TTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTNGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGG
+
833#.!+A8F9$.C<D%,DF3)9!?C>*3#*D;$3DEG=):5!53-6!C$B.!2D#,B7=%8"+GF+:+@>!>%"G@DB).DG+/#*"/@E%-.H6@=C9@.?0B&2?@&*88+9."A8==)@.@C.4-
@r4398
TACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGNA
+
8/.7A):>&H!*G>;>HA0./6HG)9++410/:F)'?2.-<#9&=%!
@r4399
ATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTG
+
B*,>!7.*1#/&$;"=42A@B9H3'<'FAH.5-&1;.".:1)+$>E*
@r4400
NGTATANGNTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGNCNCCATNCCCATACGCGCATTNCGTAGCGGTCNAGCTGGGAGTCGATACCGGCGGTCAGGTAAGCCACACGGTCAGGAACG
+
*&((*#!#$+(+'#!''$#%&""%!$&%)%"")#&('!#*")$%!#"*"(('&#!+(+&(#%&+#$+!$%(%$*&$"+!'&$$$'#)%+'#)(+"')'*")#%$&+)&&)&+*%'))*+%"('*'!%#)%+!)")%*&!*(''$%#%%#*!%$$'$"!!%)')+(%'(#(%+*""*"$))%*+%("&
@r4401
TGAACAGACAGAGGACGCCGGGCNCGCAGANCCTGTTTCTGCGGGAAAGTGNTCGACGGTGAGCTGAGTTTTGNCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCT
+
-&97D(=:0$D$H"9?H#@D=A0"&5B+8F=-H=G76<1?0B2?'$(E8H175='=8<1$*7.;8*E@+,A4AHEB>GA646GG>9G#A2)',)5/6;!G=@;67-=:<$(&GEA#G&88E,,6>"(@+!8#?,05&0D,(9%51@@7$1>*#*F=+=&D#=,;=%.$<("++>:F-(-AH(!D4)!1EHD>>!>H+1:3$+$!8H%93D/>H<5#:;(HCF7E0:&2D,5,/"+E4AA
@r4402
NACCNACTGNCNNNCANNCNCCNNAGNATGTNNNNTNNANNTNTGNCCTNNTCTCAAGTGNTTCAGNANGATGTNANNGANGACCTCNNANGTNNGTATNNAGT
+
!!$!$#$$!""#"$#!$##$$"$##$#!!!#$"$$#"##"!$!$#"""#####$$"#$"$"!##!#"$#"$$$#!#!!""!"#"!!!""!!##$!$"#!#!"$#
@r4403
TCCTGCATATGATGACAATGTNGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCATGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTAC
+
@*"'3)&F";..;<?"6(,17@67"4>;1*"($<FF"2D5A$1"H2995"4*>09.9E!1:D$6&>#D!#*@(?3?45#85D*C;=D<'!5/7#C>=&#
@r4404
TTANCAGCTATGCGCCCACCAGAACACCTTGCCGATCAGCCAAACGTC
+
(#$!+%&*+)))"*###**&!#!+!"!(!+++&)&+$$'%('*(%(&'
@r4405
TTNATNNGGNGNNANNGANTNATGTAGNNGNTNNNGNGNNNNATNNNNANNNANGNGNNNNNNGANNNNNANNAATNGNTCCTAGAGANCGTGNCTN
+
$#"!#"###""#"$!$$$#$$!$$#"$!#$$"$!$$$"!!!!##"!#"$!""$$#!$##$##$$$!"!"!"""$""$"##$!!$#$$#!$""#"!"!
@r4406
ACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATNGACAAGCNCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATA
+
E'C%3B!E$-1#H;2,C"6E<(=3HF2:&H+/;F),(E+2**/:86<H,%,8#A04):68B(@E5-:CD5"&)B.#/?9B9#3A9*!>'$>GC!%5@$3H)?$F.D11%8A<)?6)1A<*+3@F8)8%*@9%F%;<2-!"'9!-,"<B<?*)02H5$",HB@:4*<"7C-#F1E).1@>#9<($;9*140(*
@r4407
TGTTTCTGCGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGA
+
F+$E"B1@1"><-$B-E#?G6('&?,=B1*B8B2)6B)(C<<%E:,,@2
@r4408
GCTGCTGGAAAAAGNCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGNCTGTNAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATNAAACGCCNATGTTTGTGG
+
D,??@/83<'4.!5&'$67=DB5",G;A;GB'3>:?@/D7A3/2E3B''@/B6$%0G8*(-@83)H&'*AF:$?=A<G9;'7",@=?-3BC6:%#$)2';*24:(5*80;35-)6G.=+C*C*7:<G,2+6))F,&"G>%G,'%"$(;076*0&A30!G6C>%(A90,D)C>8,233"08+B0.BE-EA*.@-0+56!3,5A&.$BH*D@FF($.<525?A>:FA6&7@.5>@%%%;9%+!#-4C='>3(8-$<($?2(!H=+
@r4409
GGTATTGCATAGAATATGGCGGCGATGCTGACCGGCAGTGA
+
#>#4>/H'BCG,9B>%20@9GH:&C*E/B8AC98E*:47=G
@r4410
TGNCNGCCGCCCGAAAGAAGGCTGAGNAGCAGACTCAACAGGACAA
+
%#%&"#+%("++'#$%#*"***")))++&%$(#%#+"%#$%'**&'
@r4411
GGCGCTANACGGTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCGTGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGA
+
(*'*&'(!#($&+!)$$%*&)$**"+*+%%))##$!'#$%&!#*$&$!!$"+$((!&($*!&+!(*)##"!"(!')+&#(##*+!!%(!$#$!+'#(("")#''+##*&**"&*)'!&!'#)!#"&')*#'+"%(("(
@r4412
TNCGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTANANNGGTGGCAAC
+
'$H0!.GB#);1@(@:<=D#A<4>@:/$,%<>#'9&D<;%6D&BG8C$@5?,/5%BF2:8!#-"C/A#2,D7#$C.>:>EC'64C@33)="H;>1C813)??,
@r4413
ACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGT
+
H?H,$*'19BBA6G<D#$$)C:%?,G12@<'G61.9>"5.3(71&F>2/
@r4414
ATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATNG
+
/11$?'H2/@30C<(/67"A;G"E%82'1".:H23D/4D*8H/@A?'</9?B:G6F4*-3D%1.8H.(#1A
@r4415
TTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGA
+
-E-EB?@D%!<"-0?A*D4/1!HHD(B7@-!DE)%@9%G"12H>+A@E+BGD1.<
@r4416
TGCTCAGGTCGAAGAGATGCAGGCAGTTCCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTG
+
+'$)&)+$"$+&#&&'%**&#&%#++%)#*$"++&*&(&$$#(&*($"(%"))"%#)*))&!'#$&)!&#(*"&!)%#$%!%&
@r4417
TTANGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGNAACATGCTCTGCTTATAGCAATTTCAAGCGACTTANATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAAT
+
.=;;@.(603(-#8C6&&&@9"':6717AA!%@A,*D%F9"#*6HBF56*'(*=#GF<H&C(AF>=6-0=:""'HDF&9D%B,=$;8-?:%C:!.'*"B3?E$-;&;8-48*.6.:=&8A&2H-(DC+$H<H:H:=.90;,@02C"G/1C+006/),A-3DD05=%8CF)6,2AF$*HH#:FCC>"$4G&9!.>98G611,$,/;D2'<!,/DGG'0!#4%!;%E=4@H*(H4+8<3;!#).$FAB899:E)+13:$E.>806<,8)*0)E,7
@r4418
CCCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCAGTTATAAATCTGCTCTTTCGCAGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCT
+
";+C=-29<'>25'GAE!;)/>E+0C**56B%=32B#H/G@F09:@@)"8,G$2230D8F$"&,&5B";6D#C8B+3/+),>5.!A;(@<#!@&!=D.+AE4'E03()&=F/$:H98,GE3AGA<!'023#A9>
@r4419
ATGGCTTGGGCTAANAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATCTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTG
+
#6G%5=B6-;C-,G,B64:0)H<G(@@29>H$4(%%@<;'5B+5C5B%*+D0#!-?$62$E6$88/*-E8D,$GC4?<#>0.D+<*$@2F54$>+89
@r4420
NTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGAC
+
&4-(*&'2!8-6?+A-'.5F'<G=&$.FA+0@+C!;;E;/<>5.6390H9(ABF.;*G('C9,!GDDHE5'#AHEB
@r4421
NGTCNGCCCNANNNNNNNAAGNATNTNNNTCTNNGNAGNACCCNNCNGAN
+
"#"#""$!$!"!#$"#!!$$$#$$!!#!"#$!#"#"""##""!!$$"!"!
@r4422
ACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAG
+
H56,>)@=<'+6$("78&0#AH)%=)EDGG<4#2*1B#5(D!7-"@<@(#+;
@r4423
ACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCNAATTTAAGNTACTGCTC
+
+#"!!"'***+**#!)"%(&)")%$+*'*#(*&#+%$"$+#(%(#*&'%)("+*!%#""!&")!#'$*")''&&&+'#)!+*#''!%(**$$!*)!
@r4424
CCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAANACCTATTTCTCCTCACTNGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGA
+
H8"H6(=0@<6',9@:B)=<A(:%<)@/GG%B="01+:8723@4.?5:8D",0)><64#8"':'F01(<A=G10-0034>"2C&<B(6#)605+F>)3B>?!B,=@!G8%E,B53/+3./9+2?C<.H0E00&*$-"/+1&;(4(#ED+-'<3D4'<F6&,33#&$$(<?D#:*?!A?4=<0DA?@(
@r4425
CAGCTCAGAAAGCGTGACGGTCACACNGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGC
+
'*"!)?(-E?@C1?)=0$6<?G)@<!7?!&G.&5'A840>8?1F4C(<$749G$;+%;D@>:#;90DH4,E!(71-C3"3!B%$?(B/!(=D?">+/0,&+%3-0=/&
@r4426
TGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTTACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATCTCAGGAG
+
G8-'36C'H6D.#HA,-DG@&FH$C&4$F'A5&9%>$6'(?5*"H@)-!C.,DA3>24$-#(;F1&)'14A>4.@4*.H?==>@'=+&)C9%=760/;D!D):A?E0<.(5$F5-;!CC>E7.69C(;="'=G++9!*
@r4427
GNGTGNNCNNTNATTCCANCCTGTNCNTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCNGGAAGCACACCCGATGGATACGCGACAGCAAGTNTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCNGGAAAGGCCGANTTCTCACCGNCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTTAGGCTGGCGGCATCATTATNCACAAAATACGGTACTTTANTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGG
+
$")$!")'*&*"""*&"#$%("$%!)"+##$$#""+&&#$&#%$!&&!&+"**%+%*'(#%((&##'(()')#"!!("!+$"#('%"&)'+*&#()#$$#&)'&*)$)(%#&''$$)'&!+)*+"%%$%$$!(%!)(&*%!##**$*'$)'&%$!'$(&*"*'&&(#)"#))(($*'%!(%))#*(+"!+()&**('('*&((!*+&*%*$)))*"+*#*'"$'(('%%*!()!("+&)###($''#+*(("'*"'!"+(%$%*+(#''$$$)$+#))()+!%*(%('*)*"+&*"#**$*(!#')*&#'#%"!+$(!)')%!"''*#%"%")$%$")"(%$$*&#)*'(#%$(#+*!)%#))$""&$"*!"*)*!)+!!$&$%''$$%*)&!#$(&'
@r4428
GTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGN
+
'1A=37348G%@,C8=-=B2>CECH-$7-*#A&&B#!7C9/;F,
@r4429
GTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTTTTACACATTCCAGCCCTGAAANAGGGCATCAAATT
+
A:)A:A!)7./00)'%'2"H?*45$BA%06<.0(A07'FE&B+)&<H'H%5%H+"?)EA%>;+A08@GC@0:F>$
@r4430
GANAGGCCCGCAGTTATCAGGTTATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGA
+
%&!+#"(&'!+)""!+#!&*%#"*#(((+$(*!"))""%+'!&)*&%)%#)'+%"##($()$%$$(+#(*&'(()'$*')($&+*"#%#%("$+!*$&$#&)
@r4431
TATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACANGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTT
+
H6@F@(#@4#%93'-D)5#'(,8)1D6=2"-'.7<3BFC4%7>4(%&;0/)1BH9*(?DG>))>=&,460.'0?171A&<*=/(;@7-;C2?+'E;?;;&+(,>:20>,>F$C,-@"BG''-12D7."5(.1-&-=*.#F+/BCA=?(BH#E9DF0:#8@D>*A%$#>7,338(.3,3BH>.3G#7D-B-'"4EE.0=&5$#+61?+0>>*$&;*-<2(3;:#+'-;),,>"1?D"?1G?.%/%E!-:C&=;&<&%='G
@r4432
ATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTA
+
1@B39,>H>(7"8;83F7G92E:B&5D#7*F0@A(@?>E@95"%C':'$>%
@r4433
GACTGGACTGCGACCGGGCAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGANACCCGTGCC
+
;"),?<5!EH;H(DH)).@-=C.GF0'F</<%<>51,A0."8+6B":31"7:02)@F!H/7F!=%BE*"62@A/12*.04"1-0"@1C-G*!!FFC4>.H8*H%<"?9)<+8%"?B&$1,&404#(
@r4434
ATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATC
+
C9:EA/?A4>CGB(#A!AAA/F1A$A,3F-/571.!H,:6C@
@r4435
GNCCAGAGAACAACNATNACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTAT
+
+%&%$+((&+"(!#&*!($'&!'!'!#$)!&)*)##+%)*#(#"*)(!)*"%$(#(%")%)*))(!)+)("))++(+*(%+$"
@r4436
CATGCAGGCCGAAAGATTTTTTCAANTATANACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAAC
+
:3)>,="::B:@'0;'9%4.HD1F<)+%=#:=@5-D7B!*;-G-C8#+$#0AFA==;3+H#A@<?:31<&/2-H$(DH,<7@C!H>;E4
@r4437
GANCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGNGGCTTCAAGCGCAAGNCGGGCCTTTTCACGATC
+
!*%)%'%+(!+%#$&*$*+"&+%!+")&(")*!"#*'%(!%'&$!%#!%%($&$$#*')"+&$#!!()$"%&"+))$*'$)!!""+'%'*!)+#
@r4438
TNTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATNCAGGCCTTCACGCTTCATACGCGGGTC
+
)1%%)""1?7*=!EGB:,/',%/7*80)D>%#;0%-3B'</H?7168'EE@#'?(C(8+.AB(6H*'%))D0',1/06("B@6*AHCHD-/.;14!)2)*G
@r4439
AGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATNACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGNGGGANTGACGGCAGATCGTATG
+
D=.>%G(#3-@8:(%;/B)H1-61'@-,6<F!2,-:8$BF<7A*E#@>==B5>8H+$)16B(3'59&9?$.(A!':9,HH0/D-%3-G;2&!31,F7A$*<;AE7+3889<<C9#948$G:B/D?-B97+E$G"C7*,G$G:$0$/66<2A"><F10<1B):E!3#B$*/H03-;C19'H<491B"=!4;4*="@9*<5)
@r4440
GTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTGTGAAGGCTCCGGCAGTGGCGANTGGCGTACTGACGGATTCANCNTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTG
+
*&'+$"+(''''##*$#++#*)#%#"+("+)%+(***&%&'+&'#'+&+"!(*+%*%%$&"+&")(+(%&%"#")*%%$+'!&"*%&*!!$#"!!#'"%#+%&!&#%(+'*''(#()!!"*$$$#'+$)*)#%)!$%#(*+(&"%(+*&$!&))"!"$&%)%&'&#&(&()#)&'%'!*'"+'(+**"'))(&%%&!!+('+$+""+!#$#++&(%#)"*&")&&$+$
@r4441
GACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGNCATGAGGTT
+
(<*)>@H>;<+A>!H.)<-%",84>03@C6@"3A/3@);*('6B*@/8=7@>3,7/G!$+6$CCA=>52C)#%C'=CAB>4CD;7H:(7A@="/5=E9*1,40GH.A04'.4+',.>%9+?&<!<#%+6!HB!"'=,87:<.:,)=A@7CD;$(5+H8
@r4442
NTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATT
+
"87G6;GE!A8(+?1E*6!%)&&EHEHF!)B2<C@AF7-&*".69&AG=.+6CE.F,%4*3;##A*G1+>/F5HBF'%8!;*'=C3E2,:C99-0-?$E+/&55$>8/F$)>%E4$835<:B(=797CCB0>@@*@B5BA728B)D+'+&-:</,H::2/',"=BF:B8.E%9-5D8-6=,3F0"$#A63*0><(&97+
@r4443
CCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAANGNACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGAT
+
1"6>1@#F16%4H><"923*GF?-'4)@567H0B'-9::$2$D..5E&#,75/&4869:0!#G,G(")>20=/<<?1E502<./,CH9:?CF=!B0A522'9?B
@r4444
ACGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGNACTTTTTTCCGCTTCNGTGGCCTTTGCTGATGCCG
+
'31&G>8-#<==C5+%1CE9&4?F<(!-E$B<!E)%080"D=A,>(H?,+8A#,,;F96%B"6-53?-99%=:8.1<F@2E'
@r4445
NCGCNGCAGANTACGCAGCTGCANAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCA
+
!%)$"$'&'%""+!'&")!(&)"%#(&(%)+"##$(#)#"&*+'$**$#$&$*#!(+*$"$+!$&$&%#$+"!++&!')*&+(!
@r4446
ACAAATCTTTCCACGCTAAAGCATAACGTCCGGTTTCTTCCGTGTCAGAACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAAT
+
429&&$.*?%?#"<4?(,=.$>BA&"5FA8EG4HC$A;B8"9.!5%F)B$3@/(;B.)D9!+D83G6&6='B#>1<'5:D*7D!@#)#A.G<8H6-/GH!HG!F"*9/+16??)+3H0/'5;)B(&',:,*GGC&=*:&-6"=+H>;C;DCFC1?/->B-E@9"1AG(=2,"4<2<E)3#B'>(6)+*3(5;42@89*HA48;!+".A#+C24HC,30>>23
@r4447
ATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGCCTGCGCGGGCATTGCCACGGGTAAAGTTGGGC
+
-7(2;*%,:5AB8!3$#BG)H7AB>.H:5D9AD($DF9<$9?!'&9ADGA&)G,BH:F/+>A:#&GA/E?F(
@r4448
AACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCC
+
=H$0-1F<9B0,A>5(%G?1'4-1)=+H/<;'6A092GCH%1!/"%7,
@r4449
TTCATTACTCACTTCCCCACTTTTTTGCAAANAGAACAACANTATAGAATATTAAGCTCGACAGGTCAGTTATTTAC
+
66'2?/8:/53=:12'&25<0C$3>94-<C.-!4>!256<7#5;#=HE:E-;+>5"&?$8056#B370-8/G0H+F-
@r4450
GTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGC
+
8&F+$B,@@7CF##2B=953F(#,'7!H1%@:"461$+FDF7F)2$A1@B?H0@50:=5>F>!.E87B>5HH+/?'FB$/E0/#B*38E38"=!(."2:'"35#2?:$C$>5%'0A@)>:=5=/<GA5F9(*#
@r4451
CTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGANGAACTGGTATCCCAGGTGGCCTGANCGAA
+
:$%%+8A/1G$0-=:,8C,D4,H:3@+G*C(>AC>EG.E%/,*A489>@:H*$@68B0)72F13#
@r4452
TCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGANCGGNTGTCTGCCATGCTGCCCG
+
?01>&6"9A)$>?6C57>:"2#FF=181+(%32%@)6737%#=!7"*D22?6<(G%0;/1C=&AA.
@r4453
NNGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGT
+
!)?G%?21-*"@4G8,-#:E).G4?=F")8G7F'-EF>)!,A#2HF!;.8B2C.(,.(B2.B05'C)4D132B<!4C!1E*&CGB7)!)+=.3D'+#4;82@-$&E09G
@r4454
CCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACA
+
>A"F/&C5(#E*%*E3-,F+2E81%746<7.!19*!A!F<:3>/A:9%?,2=CFB>3>(3-F.0+))G,.>&D>>,G"C8(1""+6&#(=:-@,(73/8*#48D,#G$2BC>'=4C:+:4
@r4455
CNAATATTTCTTTAAAAATNGCAACCTGAGCCATTGGTAAAA
+
*#+)$)%!"+"(+&&**'"#'(+$#**#!*(%")&+')&%'#
@r4456
CGTCCCTGTTTGTCCGGACTGATGAGGTGCTGCAGCTGCGGCGTGGNGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACC
+
2+2C(&'.G,F&+2F/<26"/<%;1;;G58F')$37(FE%294*#C&F.&4B%+H*,).:4-,H(H#?H0%7F./H/AD5/>:<!"4FD05@9';FBH:;.;AH(AG'F/56C?F?#(/"1:%A/"%&0;45=#.5+:1.70=EC.33CD,4'>5%
@r4457
NNAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCATTTCTGATATTCCCCTCCCGGCGATAACCAGGTA
+
")&(*")+$&)"#&"&(!(")*!'&%&!'**'!*+)%"'#"&#)"(('&+!%(#'%"$#"#+$$&!!*)*")#$$'#$("!$&
@r4458
GCCGCTTCGGTTCANCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCAACGTANGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCA
+
40(.!8#=%BD:3/<>H<+/6C2A$G<'3)0=@:G.,@:$$9#!&$"'##/B866!:/D:@D;H44.#%<4=;)2=<1)E8",*:B2<=&)#F1*.$7';6/EB1*>2;9=<2D;79.;221:03&0B)=04+**+G'<;G#E($0G4.?"(1F33'619B#FA5(56H6>(6?GF3
@r4459
CGGTCTATNNTGCCGTTGTAACCGGTCATCCCCGNGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTG
+
)#)#&"')!!"+#*)%"&*$'"$%))*(&()'!%"'($")**+!$%(&%#'$)'"("+)**"("(*+$(!'&$*)%+(%*""#'&#'))$*&*!!#$)*$#($!"'&*!##)($)(**%+""%&(
@r4460
ATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGG
+
H'F/E#-+'B%-AB!:,0+<:H(;8BEE,#+26%=)/11=F@B
@r4461
CTATTAACAATATGAAATTTCAACTCATNGTTTAGGGTTTGT
+
!+(""(&+"&("&"!"!+!("))*'%)$*#*+&%+&*'")'#
@r4462
NTTNGGTATTTGCTNCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCANCCGCGATGAACCATGAGAACGTCGTTGACGACGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTNCANTCTGCGTGCTACTTCTG
+
"**&)+%($!(*'$('+%#""#)'$*"+%+'&("'*((+)")$+"*#)#'!+(#'$%&'")+*$(('!*(()+%"'!')!(#!$'%$'+''#$$!+&(&+)!&%)!!%$&$$(#!&%"%+&($(&*&!*#'"#)$"')$!'"++%&&&(%!%)''!+'&%&++%''&
@r4463
TCGACAGTTTTNTTCAGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCNTTTNGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCAC
+
234#?:BG3$H0:@'=1;&GC&7)!4B$!:&0(--@7DB6;*:<>E>.==:8<DC8'=#<)%.71600"F+(?**C>DF5:02<?D(;48;1"1&1D)4?!8H:#H@1G
@r4464
TATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTTCATCCGGGACTGCAGTG
+
?/=E%=E=59;16H4BH3!<?<**!.F=34%D&2@!*C+:;E0=+FA&!!@$#;#F/"/.
@r4465
ANAATATTACTTCAAATCTTTCTGTATGAAGATNTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCANGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTG
+
7A?50(:%E4(.12F';H"@H2'</!D'?HA'F2$9@"7C%3>BC=A-%&<@-+H>CE%80&34+=2'D(!*5BC630;D.3-@=89*>#5*>:1#D).?$=<-"?9/+8%G=H$!&.994:.4D(C>-.'18%(+;(!1D,1:0!7
@r4466
CAAGTACACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGCGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCGCTAATTCCGAGCTGGAGANCGCGGT
+
5339*649='6#9!F(7<:6E2>E9?%(C,%"*>1#AC%%#BC/"$50A="HE5A!9H"<@D.<$,>#+G--1E0)/:G$A=BCEG!3>#,@3'F3,H;1%-8!<%!80@2#.5G58='7>43B:D5"-E9E;",(%#A./;;00&+D>:->-C9-,('1*F3")"25/1943$
@r4467
GCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGNCTTATCCGGAGAGGATGAATGACGCGACANGAAGAACTTG
+
D37(=F08E->A/*=;#9;E%3-8$'.?,8G?9/.;:$4-2>F,A%+H,$-B&+@-F)H/+$3F'@";>=3-<!")A-$B9!%*FAB.<D"#(2&;2
@r4468
GCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGT
+
>@6)BG3*2';+937&53D88;/D;C22&9:,H/@*G@.&-=G$=2E="DFC(+F,(&>E7!8:=)&&G&,;/4F),38535?+)7@"D?'@.=C$%E69:/.,2<(?G,%1)"*F)A%HC
@r4469
GATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGA
+
H0%)8C-<<@5@+422<B!*9+-<.;%C*6D/EE>-,#$<)"E(+@/3:+D7F86?;=3
@r4470
CTGGCTGACATTTTCGGTGCGAGTATCCGTACNATTCAGAACTGGCANGAACAGGGAATGCCCGTTCTGCG
+
8@C:1@?1.'9;=!#H>&A-H>B5D+4+)-3"B&:(1(!2-E29H%-:';&/&)*GBF?:<59+:=&D?<'
@r4471
NGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAG
+
!>C.FH&B2,/?'&3H:@0*B".*+&E%,(H>&$%:1->5;
@r4472
TTCNNTTNANTACGAACGCCATCGACTTACGCGTGCGCATGCCGACGCANAGGAACTAAAGAATGCCAGNGANTCCGCTGAAGTGG
+
"($%#(*)*$('+&)+#+#+'!'*&'()*"#*(!())"!)!")$&+*"&(*)*$&*!&##)!))*%($+!#*'!#+!'$)!%$*$!
@r4473
TGGCGGTGCCGCTGACCACGGCGTTTAANCAAAATATTGAGCGGATA
+
326:/%(1$=3!D1:@77F-<?C@,9-3C3997<B?+'A/A@#BG</
@r4474
GCAGTTTCGATTACGGCACCAAATCGANGAATAACACGGGGGC
+
,"-(D1=29?>,;0G;=%!>,'>/F:40?=*@7942/)B024>
@r4475
GAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCC
+
B0!;6%@B*+C'E-<2+1-*""@,G"7*F5.97;-+H)&4.271:(G2!#0F2#<>(4.3&F4&*/*4-@!3>&
@r4476
GATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCA
+
H01'>"A16>ED*.H6E)/'//6/%;=C)HG/&*,C7?77/H::%>2G:)(E426HE#2HGA5&
@r4477
TAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTC
+
E8G8/G=4<"16-"E)4--FD56'<#:A:=CDG8?ECCE0"
@r4478
TGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGT
+
0"@AC#E3'H;BE".E;,57A$D81(??(0"6;C0<#8/*8H8G9337?:));/-A$<(5#G6
@r4479
GTCAGANACGGAAGTGGCCGTAAACTCNACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTNACCTG
+
''$&(")*+%)#*(&%$(!"'!*&"+(%"("&)$$*%$($)!)+')'("!#%##*($)!*&%#)*!%)""$
@r4480
ATTNTGTGNTGATANAGGACAGACAANAAATATAGATCATTTTCTTCCTAGTGCACATTATCCTGAATTTTCG
+
(*)()$$$*&'(*)#(#+)*&)*)'#++'($*#(&#!#$!'#+$$*$%"#$)'*)#*#))'$"'""++"""&'
@r4481
CATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCNCTGTCCGGCATAGCTGATATTTTCAGGGTCAT
+
=-%*-;9C!@$H70G@&:(3./!%98G?E<>+5>&(:.>-D#+C+2%==%<;>"G>@1&62%77<$()&3-/)-C:+601)
@r4482
TATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGAT
+
/7'0-.H41E.A%H+?4H%;G:G=C+>4%H"+5+')96!E&%!-3*B1(A9A4G$2)'9.E#*%,;"
@r4483
CCCATCCGNGNTNAAACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATNTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCNTGGAA
+
*'*%&)%##)#(!*!+($'+"&$'&%%+)*#&&**"+*%#!()&(&*+&*+!)$)!*#'+*(!*%'&!#&*!+)#**%!*'")'!*&#%#&+&$!"(*)*%&'#&'('&'"("&!+("+$$%("'++&"%!$"#&&&)*+(("%!)&%'**)+''"&%!(%$($$$*#$#)*+'#(+#'$''%"!+%%)!(*')$+*#
@r4484
ACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCA
+
&-%3A5540:C!3,<7A4H4),1(&'=C<@*8A61;G;+=,-;=AD&!7599.D
@r4485
ATATTGCGCCGCTTCAGGATGCTNCAGATCTGGAAATCGCAACGAAGGA
+
61=D>/!F2=!()=!G9)455D(./H1@A800<&?<@4A!=5<,B:9H8
@r4486
NTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGGGTTCACCACCACCGTGGTGCTGTTAC
+
#+&#%++**('#$"##$$$++$()!$(+'((&)!!&(((!!**&*$$$'"(#''#'!'+)')#'&
@r4487
CTCNACAGTGATGAGGCNTCGTGGCATCTCGNTGCAGACCATCGGGGTAAAACCGTCTAT
+
+*F008/"&G4+"#(.<&7;)'F!*7,#E0'*H&F3G"B"8!8=3.(,1B#=,703!>,-
@r4488
AACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGG
+
72.(G=569-597=0!"'*4?5EA028?+FH(%;=1E#+$"3(9B;":%+@*68.B6E9)*&/E1!<04=$0?7":2%D;/8>"7.1
@r4489
ATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATC
+
..',(0/94:61B)*<,-D4$7+)58=1>3F!04B'=56<5AF7-":=:BF14&8::G=0.E*-1)1-C?:/*#52G/?@*
@r4490
AGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTANGAGGGCATTGCAGTAATTGAGTTGC
+
2-9*5.-1*7?'"4=FA$1;.0FF3<F2FH<)*B),=:E0AD%+6E'+694";!4(#CG*1*D=ECB$066+AD+'B?D5&'+'7C
@r4491
CCCATCGCGCCAGCACCTGATATTCCCCGCTGTNTGCAGTGACTTCTGCGGTCAGGTGCTGCACCG
+
99!10C1%85=5$?A.,DA:"@(:69+)0GG39D9!:&GHE.-2&7,<&07='2"8E'-4&*9)+"
@r4492
GCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCA
+
'54$5$??58-208D?7H5)@G),%E883>+BB):=&<+;!>=H!!GD>(%!7A&E#'C%B7++589+>)1*CD!'25H1-C201F/$<%"><G!-A;<1G%1/4:G:FCG8$38$/B;65#".59+-&@&-$,>/2@E,*HG&EG'>@:@;#'CF&AC.%931+/A,E-+)%'%&01/:>E#DG$,
@r4493
TGGCTTTTCGGGAAAACGGGATCACCACGATGGNACAGGTTANCGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGNTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTG
+
8A)="5HH3607&$<056$:0/%,5B%H<G@6GF,>FA9'<6A:#6!:&$"#+)'(9"%1&E@B#:$2(:(!6HD,.F@:59<?5C700;=E*F=:+!'<-)/84739;(8)!8&.)+/:8!0:@"DF$,/A;,6!6(26/=/FFB2<AA(7>$EH4331GF#H
@r4494
GATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGGTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGNCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCA
+
.)-0;:4!"GH+(=."3.4=7+9:$D,;82;/E=90.AG0$$D,8FE0&)!50:,$B4#(33?).E&9<2F)H$?G-;$""%%A-)547B'#"6,D>F5E2-B-EH)12+BD@6@78/:A4$9E+2324A4>=1<&D724,<=:9H&D;7G%+./"/8A7G5'-D3/'6,(3,>0-?(3(5C+=$,&(B"*!H42;H".@7!&(10'AC'4/0?<HB"!:'&A#!):&5A@$H>0+&+;$)/*=9?>1,!4'3BBFA0,D:*6,#G6>$:7-EA"$>9
@r4495
TGCATGCTAATGTCTGAAAATTGAGGNGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTNATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTANCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCA
+
!'&"!+')'(%*$#&#)+!$!)')&$!)"')#"%++*+)(((!(#!&$"&%)%*"&''%*)'%#)+))($&)(+!%&)')'"&*$$&!$(*'%+!)+**&)*&'*((*%!!)+!()$&($*($$&$(%(&")&$!%'&"'*)%&!&)*%)($++*'*'&$)*(#$!'('$)%$'&$%)++((*(+&(+)%*##'+#+)#"%!&($))$'(("$)%$&
@r4496
AAGTAATAAAACCGANCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTANNAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGA
+
8'G%D#9!?E@@?@71?=;)C>@E(C7B18DH8*?680(:-:E'+2A3G3431+"G34;G4F#7H5:GDD#2/=):?740BH'?>2>4D"#!>07CB+G"@%$G"7,;-62CC/@B:&
@r4497
NGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGG
+
!%BGA)#<!CG;%86E1@71'0H.FG'0H$9B<72"0!+*+2=D/=C$5*",!F%?>@3$4$5-BH&/+91=0*<!:+F
@r4498
TGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCNGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGT
+
*)BH=+?BA<'C0@>0GF-8/C*D1#H-,>#G&D/B$(-@DB#91&DE0&33+72#!8&,%:?05<);./.<>?8E>4&H)+';8#.#D(:(&/F:?.%>+(:$-*:B=)-1&4D*%85H0:9'G)>&E=#.7%55./0G&>AA@AC.(>(=220AAEC?H$3E.!>
@r4499
AAGNTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCACCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTC
+
,55;C49*AE'/,0&6F$<-6H=)"H6!/*2F,0F/!C@5#3H$#.(25&:D43B";"?8'&8/C.?#H*,2!9&(B1?2%1*'DA7E'G<C>,;-C@/1,-@5##.C*->E4E
@r4500
ATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAA
+
#@C7,H85(&=(?);293B=3H5'4.(."H!!7;2-H!22:7"7$&
@r4501
CCGTGGTATGGCAAAANGCACCGGGATANCACGCTCACCATGAAGCGTTTCACTAATG
+
(E6=.HF$A9)2+BD"5$>+?(F>>2#=.FDC-0)7&3"A?6!*B@*HF897E(-*',
@r4502
GAATATGGTGCAGCAGCTCGCCGTNGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACANCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTANGCCACCAGTCATCCTCACGATGAAAGTCCGGC
+
:5CH..A!?:/,(9+7&*:5@F03++!+'=02+,(0)%A+4@-8=7%&,:$F=?5>0-:F;9EC#$A,"'F15$24-G<!>?@90)?0>5F4/B.B2G27EF,@%6(;&.:@&21A&48+C)"22A;!*6?2'34'9.@9102/BF?%-E(#0@1B053*;G??A+6'#CA>3C..F5E$B4!2&3(5-=79H,&:8
@r4503
TCGAATACGTTGTCATGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGC
+
('#**+*$!'*)+)+)+))#%'$!%*%)'$##"#&'+$"%+!+($##!$'&$(
@r4504
NACNAGCNACGGNACATGATATAAATATCAATATATGAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGATTCAACTACT
+
$*%%'&'"((*"&'!+"+")'!$(!''"+%#"#'%""'%$!$*#)"!!!'&)(##*#&'(!*%$"*+&#*))#$"!*""!&!#)'*&(*((+*)+$!$"""#$#"!)%&($&%%
@r4505
AAAAACTTCNGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCAC
+
*&(()&(*)++)#!$+%(!$&%*)'#*+%*%$+))+(+($'$'#(+#*##"'+%#$&%()""%"$#%!"!*+$!#(*"'&"&#$$&&$(&("!%*"&"($&&+""#"&
@r4506
GCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGC
+
2=?!))H1E$9G2C(1C#BD->;@?-74"1.6-A5&!AD2<)"B7+A'@7;0
@r4507
CCTCAACGCGNGGGCTCANGNTGCNGTTAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACG
+
%%(%&(*)&&#'*&"$'*!#"")#%&"+#'*!)+#!%%))#)&#$+)*"$$"$)&$%!)+"*$'*%%#'%'#$*'$&!("+*%$$&&++%$&*$(&%$&!&&"++())
@r4508
CNCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGNCATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTANCACGCAGNCTGAA
+
#2:*=5H5%E)18?H4=.#>*(30?;@'#EH'=#&;&7D9:-E$G"6:.''?1F?,8@$5";-A",?#4@%@B=GE=(,+F.,EG;/5+C%94??<10"<AF-8=-B3+F4!!#0
@r4509
ATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGC
+
+(;&D'=/0%)$.=G7B&.!;:?@3&%>+$!857+*H(=>''/220*-G('?(G;3"B78*B
@r4510
CATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGTTTCNGGAAATCAACATGTCGGTTTT
+
.?G97E-@26*=3F*$2)15->G#>&AF%D=(?$D#=9):>H;/(?E@6C7#CHEH)F#C+H:@19-&E
@r4511
NNNNNCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCC
+
)$!$!+&%)'%)(&+'$%*+!+*#&$'()#*')!)&%&*%*'''
@r4512
GGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTG
+
%==#&3=3C;C2EE>:C'1<D<0@+;'"H/(<!F)>G8%#;@827=D$"A"?DF@.?()(-<74B%$);2;=!<-,6H<87-/"151&"A04FG%A;H,/*3"AE9@E")00((">/
@r4513
GGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAANGTGGTAAAACTGCAACTCAATNACTGCAATGCCCTCGTAATNAAGTGAATTTACAATAT
+
'':53A)>;HA3<=9,30F:'859@,"B"5'C2>C+#?D21%2F?)(,.*A*FC02#59%FAB6@:"-,'C$A:)5-1:!"%7B+$+B,F2?A#F+B=%1&4(!BD-"GEH',25#&*F(:1#;>@$'6"(&).D#4C:++C=6H*8!$;#51D*D!9
@r4514
TGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCNGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCNTAGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTC
+
@G&$BA,9)&.19C>$;17>87/D;$(#F)/C$11A<@?=))6*-B4:9::2G%B1&A-)83C(C@&48(#=+*/4AB-<0F@F>.?(1<!0!;H'@!A"8@'B>=.#6"$GB,4>1'8&.=*)29GA/!;&+9;#95%2EB'8DG/6&)0(A@'"6E@59GA.@D7@F=/6=3E(!!<-
@r4515
CANCCNAACGATACCTGTTAGCAATATTTAATAGCTTGAAATAAT
+
%#%$(!*+%'((&("''"(&%!"+#(&))%''&&%#%*%$(*"$+
@r4516
TGTGTGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCGATCCATTTACGAATGTTTGCTGGGT
+
0:4-/#/)9=+#"1E)63$H%*3D/-:!/,#5<AF,E1+@66,>&%:2?!CC(+-D*0:H*/:<%<5$.-C%=37?C4/8:&=6":
@r4517
GATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATATGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCC
+
7:@"A*81A2#@,0360;&(!;"<+"(E19%0.6+"-*GHH4G4/32(A';>>6:5$'!A2$#H5G%E.=F12'(A/6=HE$$AA:C6H.$7-'#79('H&B$HEEE"'7"4"07''+B-+F)17>.,<++6A2A7(+$3A
@r4518
GAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGNCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGC
+
/<'(%0F039D!<(%G?#%E2,AE;<H.H";8-&1%>,D3G&"'=;#?<69"63)FG:3D&.7%#D/4GF:7:./+>+(F,1!D'<(D&<)39)%.*$6AH&$>/)/+$@A)6;7,"6GA!A*E!%8<'+(&,:F',29)>G!1?=@%D9*&3"!.&,5C8
@r4519
TTCCGTCTTCACGGACTTCGTTGCTTTNCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAAT
+
,A2475!02::1-$C."0@#4"&>G,"*%%B<)$F2GF,?466*"G2(+45;0D!<6(3&$6=1,BE,0D/<8#H
@r4520
TNAGCATTGCCGCAACTTNTTTTGTGGTGATGTTCTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTT
+
+3?5B!%'0.(><G+ECA)+G7&6(?"-:$#2DA4D9%$*+&/--;>E&9=0#60>#"H3D$$DC&HA/;-97
@r4521
TGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCANGAGTAGAAAGCGCACTAAATCCGATAGACCTTAC
+
A5DA*9&=(*<E"=B#+(%.")6D&C'0*3).>,%0*#D6G2:2H;?"?9)D.:166E@D4!#(<2-,<CB%5-'$+.2<>36=38D#B.!"26-?%*6E
@r4522
TGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGG
+
F-;6:)H5HG&)H>*/"A-??&034/$6<C@!*-F==!:7:
@r4523
AAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAG
+
-&;11GB.98GA7<H853A#)H?>BG+=B(F@0HH4.26:!5
@r4524
AGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACG
+
G>B,%@(+B!G7'7,!@?D(H!>;87E<4$.9".2#B+!2"=E7*:E%GC->*?>@%F/337CH0';;13#5%=47B
@r4525
TGGTGATGCNGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCNGGGATATTCCGTCGCTGCTGGCGCTGGCCCC
+
(+)($'"'**$&)$!*"(''+))%(%+)+%+'%$+*'"*(%'('%(()%+#%&##$")($)*$%$*&&#''"+#'""#
@r4526
TCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGGAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCANAACCGGCGCGTTNCTGGTGGCGATGNCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGNCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAA
+
-5&4%;;0H;01>=>"CDH-5/""(%0BF;.&.(;C)"D+!?/5-2;DC+((B42G(7#H'-?,04*D3)1++!:E')@#&0&=E!&H*@'&(7"2(>*1D81(:F;7(:HB:;&*A1"(892(;FG)<;/3G">H1(<>4!3@D9?$A+00@&'(G<!E06/0D+%6A*-')?<:,&8!>6FF2CA>86125A)E2D271.?(98-2%4.F!+#'G@
@r4527
GCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGNTTGCCAGGCTCAAATGAGTCG
+
4%1&?:6.:6+>B1,>.'@3*=E0>AH1BD8CB;7,">F.)37#./::49$.=D4>9B2(@):'@9%-"76#8;%,%&'DA$G.'C,@&)67,(!$@9FH%E1+7<00&:)12;;1D31$*A=-,(8.!H?2*>6"/&B!19B$F.?")*@?G2,82&!:.C'446%A-7"G/;#*%B4A!A>5778/7%C6(4G>-B+-=7/$#26//=HG6>;E@#<*H7'2/2G:/5E9;?+6-!
@r4528
GAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAG
+
84A#8F6;,G/?H138.;'!8=32F2B+!=445G4C*&D+E%),4<@7&$6!GA'66B39=4>G%:3EA48D<!1,5$-%80A8H.4=;;F#*
@r4529
GCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAG
+
1B3.F1#DA3"763D>5/EH8'&27"('6(8(5&H"(G74!7'361D!%8E.9@/.+*-#<3E"#GH(6%>
@r4530
CNGACCTTACCTTCGANAACCAGAANACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCG
+
)'#(+&&#**'))*+$')!$&("!*+#$$"!!%)'##'++#+$)$'!&%%+')+!&)$+%$%"#*))'")%'+$!#+")#$)(+&+#*)('$'"$%"$!!
@r4531
ATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGG
+
>,?<'/?/*.%G&5$A.=H,F+7#1$1,85)19)$!?((H"DH2"-;4":)=A1E,/86@D1A,
@r4532
NATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAA
+
'%?C2+B:>8-9.D109*=65$H<-D'1H@9*F+8;88,"2<+8)%,.*$#BAA93-",!
@r4533
GCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGNTCACCATTAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTA
+
=37F1,D5CH0=DF!",(%C6=7(;>%=4!+F;!(D?17/;&+)H62G"99.D9>"9175FB$H&$HAF.)?);:+!H.+H%+<%*5!
@r4534
TGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCA
+
8$022&%""BDG2',<9(E@C@!8$#%=%.?BH6>35<=A7563:34H9.$$%/D$/-&*8D/2=CACA7AAG3@=*!/:">7F$*D>G:3?B,%BG#/"0E1H:278
@r4535
CGCAGGCTCTCATAGTGAAACGTATCCTCNCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCC
+
,0:0><F,48F3/-D1*'E+:82G3!8*F$9=.?C37?A#@*C'.0G-B>9(>G>;D%B'F.%"2HH!B85'.'C.'1==&
@r4536
NCCAGGCNNNTTCGTTCATCTCTCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTCATTTTTCTATTTCT
+
""&$*'&&#'+#&&*!%)!*"!+!(&%'*$")"#(*''&!*#)("$(+"&#()"*)$))"$!(+%!&(#)+#"&+)*"#*##(((*(!*(+%#*$!"+%)*'#)#%%#)%*%#'"('$
@r4537
TTTNCGAAGGTTTTACGTTTTCCCGTATANCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTANGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTNCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTNCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGC
+
%+3"9.>'-;/CCD62#BD+"-C;'#G<G2<.(F.>#E!-&%.#%*;7+,,3&G!18"<@5':CF41:"BD4/;2-3:D4:%FG0"!1=/8G$6@0BC1=BB?=.064</&EF36A/GFGDDE1&>/)/5(.:1/1>:"F80E124<54BH/2$DD30=*2"/DC1C'==D--45<44<1A>6#?&DD,.268C.3)+<+E@@HC(10@C0C9>-'*1%!:6B)'F(&-E4$3$95E2
@r4538
AAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACTATTCTGGCAAACCATTTAACACACGTGCNAACTGTC
+
;6*#;D@HDD8=:2,!=>-'(F@4B;B1<;!;.D&A#)2>+D?E,D763%'96E'$=?*,<)G$HD"&$;$G:/&4+=G9'B'6=6$,4+G:0/8H2+D373>
@r4539
TTGGTTAATACGCTTGAGGGTGAATGCGAANAATAAAAAAGGAGCCTGT
+
H'82F&//"/$0F27--A=B3E$=%/,,1&6H11*BH1CE&6.0$&5)G
@r4540
CNGCNGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGC
+
:*A4E%11?:.?GH1(F@;#:*%3:8#!*=B@<')E&)%B?)1H@@C69:&FE)E@=(
@r4541
ATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGA
+
-*""B0A&1+4D>0#>-G/;1?=%F8<B*&G''F,C.+4,;C8@GE!(+&'.AG(D48(D%
@r4542
GTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCANTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGA
+
H:+%*:F+G(6'G66AF%,"F2"H<<=(:+.#0+3)34"9!-=,>3.@E/,<-5(9BD:>%+$9:3"3H3D?3<.+D?%E07/-*9&FB>
@r4543
AAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAAATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAG
+
/?7E.398A%B&%8"&;/A-&6E#&38-=(*0H>65*&9#02DG)D,F&17!<&!28>5B+(E@-+7/4(4@4-!&(?78D1.;??2.?=2B;0#)"8-?&&!!+6/
@r4544
GTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGC
+
262A>>*E?..+!7/C*G"%EC'6D"-5<9--,+<4:$3H0H:#A4*$1
@r4545
GGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCC
+
='#/0'*%;%-H337.-H8B-!+F2@/A.DE;"6E8?H10!4+<07>F3:F="1,':52+FF:1.=,&<)/=*9>D!9C&310;*@87C!C,&56=*9:"*B#04.G@)HH?#F'##*&1'?#(;7<:F2@*(HC*G*+"H7#;C!E8?67/<*+F;*=%*
@r4546
CATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCA
+
/9B,4;G!053@2%5&8!")F5-6!<4"19A3@"+64@8C31F,H919C*0E#(4A6/5;#/*61*H=H%#%+9<7-5;(3:A.479C:+F+%D9%>&!2<0EC0C/8$(H%/0+F?@*(<$<+<EFDB.'+7)9".1-DA9,C*8AH6*B?;E-<8%0H@:/8A#%E%22C$;"4'7B'@:#(==*6(#@"5489<??'3"/?FH95.+'@D)@?,!/C101/>%97=-DH/?.E6/"/@?-95(&?H
@r4547
CATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCNTAGTATTTCCTTCAAGCTTTGCCACACCACGGTNTTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAG
+
&/!!%F*0%E*2DF;%,E'-3(+.(:##$.C'%<C<.+=./(G:E$*>6)4)/!0DAH<5G2-:HC9A3('@C'7="'2((2"**%21!434)E:/3"5,::/'5/:D1)30.-/C1/E*>F,,!<(4!5G0,*1;9&0-D48*#(@"@;
@r4548
NCAAAAACNGAGTTTGTACAACGGTGTTCACACTGCGGATATAAAAGTAATAANCATGGCCCGGTTTGANATTGATACTGGCGGCTATCCA
+
#'*$&#'#!)#&%)"!!#+*))"%%''((+!*#"'+#')"%)%)"""%+$"++%'(!#!!!$)#)(%)!)+)%$'*&*%"&&)'&&$*#)!
@r4549
GGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGAT
+
.0!46'F"(?<,H"*F1)>%C0<&*6;>:0&?41EB(02!())-68C!.1.8A@.:&+C4+7,)<1#";+?9=,#GB:HA.C-%4&G<4%8)%G-$:0.H:4A9,?22CH;>!H'=B>&
@r4550
CATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCTAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTGGGTGAGAACTTAGGTGTTTTANCTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGT
+
-+9>G;7.?9445,F'0F?!!'*$+53?)4B?4H/'#3?2#>)>@8)//828E07.(3-<+?)F75"$(FBA$&:0.F,34H70"E5(*G3%/$H?E=;!1G2%<DB7#ED=C/?(6:4%6>E0AE>"#":#%'*$C<2@,/5.-G.&9A>-F*'H26?<:#9:445=8:H@27CD=H8-!<,26$*8A9<<,0."*C<)&).0B%F%0'3"7H?<%"==1.)?74#2(C>H=A
@r4551
GATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTC
+
+&%!#$&"($'*#'+#++&!+"!$)#)+$+$+!#*&$&("&"%#+(+)('#"#")%&(+!$!#'((!!+)!)*%"!%$&&)(+&!*$$!'$$(($%'&)!%"#+$("()#'!*!!'#'
@r4552
TCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGNAACCATTNCCGGCA
+
D?HD2;6-)D1:F!/(&?:<B&ED<&)-@"BA)+$+(G4,FG%#)8B?CC='8%05H)1*2B'!=**6E>@41&>!:3G75
@r4553
CTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGNTGTTCTTTCAGTTCTNCAATTCGAA
+
+"+'%)"!*+'$%"+!$%*$+)("**)(+#++("'"##&%"#%!""!!#!(%$(%!#%&'#!(*!"#!+
@r4554
NCGATGGATTTTANTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACC
+
#0=?*@C1<!#<:>1%!C:)(GF1/>2'#?,$?:"/D=/C.+)*!#8,3$H%D.
@r4555
TTCAGATGACNCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTNAAAATAGCCCACC
+
DE4$*D)B(H5G@@#(=-D6(BE<5&A,'H'-'7&A+?6B:!H'8&B=92*4"2//76A6>&%6&*9BAA9*9",
@r4556
AAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGA
+
@A&<:/'A$1,C3"(3>$'>A3:7!.";#8'4B!.?D)C4$6#&,;
@r4557
GATGGAGTCTGTCCGAGCGGTCTGCGTGACCAGACGCCGGG
+
5F2>,'@-,!H/AGH:-D.D9,&('!!$B.-9+@.4+HE9#
@r4558
TATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTAT
+
'9/H6(3%(F/D9/'C%A#A4#0=;?F/3#F@892>>?$#</D6H=32*#31.7,>@+FB./;GH7,4=:00&G$6/?CH1&9#D*$8G")-&#4F:B8,#;->4
@r4559
ATAATGCAATACGTGTACGCGCTAAACCCTGTGTGGATCGTTT
+
D4<3;$(:7,B,0%@#:/;)#).>(#,8>,9A%G;7.:$@-@3
@r4560
AACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATNATGTGCAATAGGAAGAAAATGATCTATANTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCT
+
1<6.1<1!>8":(<H)'7H+8'54*6803>0$/&';B$1">4(9=H$,H@H&&D,A0:=FF2=)?H%*5H;:+=D!:0'BF:"?7DE;05/$)D"655#2:?E-@6'H!H</9&&/&<H8B-8AD23#0*:$5$/DH'&;,+7F8-:@54=F3A/3!2/7?F'-7CE,=D./=.<<;H7F?)-
@r4561
TCCAGCAGTTCTCANCCACATCCCGGCGCGGTGTGCCTGCCCC
+
@!0D5B?,E'F/5A2FCH8GFC&GH40,.(12300+@!?'<+A
@r4562
CGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCNCC
+
8D9C$)<B$"B7"-*C0@;EDHF780C$B*"9>+/,9#2+5(H#18!4%/'7A<+F;7&A:2+$)/EA(@0,&C&%F2"D
@r4563
NTNGTAGNAAAGGAANAAGAATTACCGCTATCGATACATCAGGAATATTTG
+
"$'"'$*"&%)")*$"'+!$('##&"'"%&$("&&)!'")+$%+*+*&(+)
@r4564
CTTGCCGTTTATGCGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCA
+
1-A;,)%10?%4224AFC*8+)C8<D"9&-E;4?A2;7C1";8&!28G?9"'+DA&/*85#%-688.1$31F&+1)<D=/9+E:0?$?-;2BC/59?H-$+450C(28'-($42+$21
@r4565
TCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGT
+
87BB,;3G"?C5D<$2%.(00*)27E6-6:.)&.!/@D81/
@r4566
AAATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCC
+
83G"09<3/18=4;5AG8*+!$9(17-B!A)HC;-F%)63#<5"A:<,)%&7
@r4567
CACTACAGACTCTGGCATCTCTGTGAAGACGACGCGAAATTCAGCATTNTCACAATCGTTAT
+
?%G!09-?D.6%9&@!BFF=:DC*.;F2#==)@;#A:#%<<#,2H$58H@#$C=2B#!G%7*
@r4568
CNTTNGAGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTG
+
*$*!&!+!!#'$%!%%'%$#%$'(&"+#'#&*$&!*"!&"%!#%#)+#'&+#"&!&''$)$*"
@r4569
CGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAAC
+
&3)+B$;6=.$#:#*C:9>7$C%5?>!4=,G.D;C/C*@$$1#A.C?7"&
@r4570
TCAGGGATCGCNTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGNTACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGNCCGTCGNT
+
+&5!C$+C/1A6/A5"/6,74%6%6B&:F@3@H:$9C48)5)17E/B<$.%-9!#A!H"9DC@E0',,B02%>9!74$5*,;H8>42D+<<?62,625(H.#0/+"$@1=#,!F*.';A,5.D"F;H'DFE+C=)BC<<G.%,B6=H4##!7"#=H9<!?<743'<-#::D1GHDC5.+G2!70+785!!)5#"$---,7#1%/6'5*9#:EHG#"0:+$1E08<.6,*:<?7993&)
@r4571
NAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTNCGCGAA
+
$3B/=#EG1<&655."EH$+'/0!!'GB5@57D)!1"F$A>H;8CC=1<12?
@r4572
CTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGCGTATTTGCCCTTAAGCACGGCAG
+
B/7,%7/2%B.D";#=B'G5HB9E05%G)<+96"$>F/-,>8!B$6(G:.4(0:;<$7.74-+!-C/3.0?6B6,HD:4/
@r4573
CGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATNGTTAGCCCACCCAGCAAAANTCGGTTTTCTGGCTGATGGTGCGATAGTCTT
+
=5AE+E3#!?)4:>,+"5*'*68"G$.##"?#E78*C);B:E)40-6==?-"G93'1*!F1.B:%#2<C5*20&</%G"3:79!,.)#@8E3:;,<(FB2>&1(@7H8$(@-1'.A7!49(96)*+A8??3(H7HD6DC25%
@r4574
TGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACATGCGTCATAATTGATTATTTGACGTGGT
+
@))HF)C+%;*=0):2D4>,.!%2@!>4>2?"-<BH3D(3(!.1<!#?="=<CC"-E&6/.3?'/$<*;-F13#,9+G6@8=<166/AB."'!!F$%G9=?D8G?1#7(<$/'6E$*$71&1=#D6$<'16H5<51+:,5?<!+,F-1
@r4575
NANCNTGNCANNNNNTNNTGCGTNTNNTCNNCGAACTNNANNNGANTNNNNNNNTANGTCNNNGNCANATGGCNCNNTTNTTTNANCNGNNNGNNTATGNNGAATCTANAANNTNCAGNCNNCNNCAGTGGNNATATGAGCC
+
"!$#"$!!!$"#$"!#"!$!###"#!#$#$#$"$!#$"!"!#$$"$!#"$""!!#$!###!$!"$"!!#$$$#!$"!"#!!#""#!$!#""!"!"!!!!!$$#$#$$$#"#"$#"##!$#!!"!#"$#""!#"""##!$!#!
@r4576
TTTTTCTTCGTTTTCGCTAACTATTTTCCATGAAATACATTTTTGNTTATTATTTGAATCAATTC
+
@#C!=()17H'2+0:D15D.$+6:87C64=0H899C%5C3(9'#<#+294.E,'4+0F@,)%(;(
@r4577
CCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTT
+
4@%=<;F<#)(8@E0('D9#>*30/CC"G;?&H>B;5!1**0/*
@r4578
CCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAA
+
2GG-'H5+A$A8/'-&B'+""=;BD#2>E+0:9)AEB4%E(G9(1C;7E=9&+95
@r4579
AAAAAGTCGAGCTGACGGAGGATAACGCCNGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGANGGCAAACNTTATGTCGCGGGTATTGGCCTCAGCATG
+
0,E=%4.+6:#7=&@F6.77!2/-A;/H"@<H?%>;"$!$>1B:*7"7BC&,036($(G8"36*"3G;E'2HHD<8/>B%!5!-$$D:8>*;CF5B$-#/E89E68:1E5DB$@!66FH,4#?=.*/%(H0<5@A3<714023)$=)&<*:-0->
@r4580
CCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTNTTGGCGGTATATGGAGTTAAATAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACNAAACATGCAATCGTAGTAANCAT
+
-:9/%6/;H7)0&6)&A$1G:C!>!C6$?&A76%:.&.73610.-6@:3"A#1B$+;6(D#@12&*(A=F=.",#!A5'!2"3%);6-AG=3..$,#C:63-*?/>,61-F<'1)H$-;B0(C8/2-H=E$.BA59/G31D$/#8%'$*3"6@-<1"F2.!-$'=2G:$#13CC#G3:52D&/EG#"$%1D(@48;36/"9:+A=4=9*?F2B/.@)$<?*D;F4*!D-@7*&4(75G=70&4!9D+$62%8";E.*+>6&
@r4581
GNGGCANTGGCGTGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTT
+
'#("$)"**'%$)+"!#%+(+#+!%!*+'"'*"+((#*&%%+*)+)")''"+'#&&$&&)$++"*+++%+!'**&%&""$!%+
@r4582
ACAGCCATTCNGCCCGCTGCGGCGAAATTCCATTTTNCAACCGGAGGATTNACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGNCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGAANCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGNAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGNAGAATAACCAGGTGGTGATT
+
0F6#+(2D1=#$E792G53/-47C.D1.0318%H)9"<F3<>+7%:/>=;;/3%""H#2-6509(!,E5.4H4#C:D;4/64,="&648!@A!G(@6+*0@:E8@@!GA/:0016;712'':)C(.3</D7%(9BD6DH6::F7.7(4,%;&9CG(2/))6*3<H),H2H%,6''"+#-,H<9#)A%8%*8BF!?8<#,)793H!-B994=>F,9<(:=B8<:39<A;20$)D*>;"8'C-C1>G:F)?2.*:8/6:2
@r4583
TGAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTG
+
($*98>E6*C%D.*<B?&)A+<0;G?$=B<!+:)"D#5$1?$%.2B6*'C-,1*05=5CEG-
@r4584
GNCCGTGGATCTGATTCGTGTAAAAAATATNCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGT
+
#$&+!$*#)#'"%(!+&+++'&(**$*'(#%!()*+#'$"%*"*!&$&''*!&!(&%"')$+!)!!)*(*#$""($+'$
@r4585
CTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTC
+
67%/:FA)%24-GG>@)*B<,/#G;"'91&)11<:H=$.%:G22#:<*35F+6"G=FB*(<<19ED"@7*!8F=*G:!+2?3,E7&6&.-$+H&95:%#,3"(;?@/-H9$29673'!?G*%1-&7/9)D;D53=9(?BF94"!<6:$*.@*D(?+86
@r4586
GAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAAC
+
03-(.G$#C,8540;55"(/*.<2A@G'2E8+$=>8#3&29!627'6EC?0B)E-=7())
@r4587
NATNGCGCCGTNTTTCNTATGGNNCNANGGNTCGNCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGA
+
!$)!'''!'%*$"'##")%(!)!&*"!$*&"''&#)*+!+(&*+'!"*)'*%'""'**!$&%&*)##'#&*&($#!)&!*&#'!#"+)!'%!%
@r4588
ACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCACCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTA
+
/$@>.:"6H!++?37=3.HB7&<.0%;(91""(.@1.;H0$)#H37,2$2+$1@8H&,>7$'(G&7.F1/(?#"H?&"-*1,89$*D"3*@(3%*-C3?-B"C.:<B5,/7!C(1!4F(&@/?F:+5<F<$-/D7!AHB<"!'9(2%9G<!$=H+&&.3&,-D4&%+2+)3#:'@<!""8%9H0/+74*:8D>F+0#=-,0#ACB#"7%8&3*F+3H&&,5(5.-.=1(:G:A@79$"
@r4589
NACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATNCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGCTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTC
+
"&$+&#$(+''#%$'#%"$+)(*&#!$#)&(*$'(%'*$)+!*#"&(#)'+(*+*"$#+**#%!"!#!*%''*%&+'&!+##%#'$$)""'$&&+%#$*#()($'&'&*"%*'+(*&!%+%'$"#!"*!$)#*'$"%+'*'**++#%(""'*(")&&*+)""+(((+'!""(*)*)%(&$#$*&'""'%)*)+$(&(!%(&"''!##"(#+*(+
@r4590
TCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTNCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGNATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTT
+
=3'"/6?(EFAC9'#+C?ECDBH@F:C*3()4.:8>!-HF4B39C-%3H6F)?G,C;+;E2;7(%64B;)/)?F'&-2(E2A=?*,+2;0'9!$G&;F+44D4B8FHAGH#0"#-;FC<DD+-9<*'25:7B!*''H!@-*4>)+1>4)4@F8H#/:"7",4#$%)H/(;5,-5#99"'-(!)984<1CBCF.?76=(>8"78/6;8,?)D';26$2=<*(F+>269A49G*"<.+A7*B"2#B166H"5<&D1E7H(3(*'4?:9:-CE762%?'!2-
@r4591
CCGACAGGTTACCGGTGNTTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGC
+
D0>9!D6#?7,*"5-9-?922F&;B@6F8B:-CBD'G%2,?;8/5!:G!0.DE:-/2=C/9@4(.,>=//*0D'(#7F:2>=4CB-.$58ED/=)2B4?B/0<.B/?.!4H@E";66+4
@r4592
CCATGAATGAAGTCGTTAAANACATTGAGCAGGAAGTGCTNACCACCTGGCCCANGGAGGTAATTTTTCATGCTGAAAAC
+
(+=+?%1+!"<A-/?A-57;';6(/818/.!(9$'$5=D"!4A32?*(1@2>+2/2E*</>C)1:G*H&/*<!6;<7##<
@r4593
TAATCTGCTGCAATGCCACAGCGTCCGGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAA
+
E@5,)-C<)4G'&(.!(($D"43B$,.6?D'=+:1+<.-7F=,&H3&<70<07C727@-5,7.;,&E5?A!<F4B-2F!G,(#CF8'7F
@r4594
CTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATT
+
2?#+G6#&5BF$1+!9C8$5-<0A>2)+5B=7ED,+;,E,=!F%=G9:5*>:',9*>!0")4335BG(1AD(>0)73/#2<
@r4595
CAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTNTTCAGTAATGANCCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACT
+
))(+)#*#"*#*!$&(%('#+)&+###%)%*%&"%)'+'&'*')+'*$)%(&!"%&"&($!*#*)(&+'"!)!'$!+)"&$#"%)"(!""(%+(%#%(')&%(!*
@r4596
ATAGGAAGAAAATGATATATATTTTTTGTCTGTCCTATATNACCACAAAATGGACATTTTTCACCTGACGAAACAAGCA
+
1$9"/8;)!B=C?>F3D9%D8$<>:>":3'5703!,"0E4A%F5=.)0&@5!4:1(=:!*A)!<B2/F2!8">=&;5EF
@r4597
AGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAGAAG
+
93+/78%<H0E/)".$B'!4/@AC5B5.5G=6+-?#H5&<!<5CG;=(BD7)3,9E':9H1)F<6$(E.>9:C%-,1-3G+<A!9::6G,#;2#=2A/#A>>%HH?90%A9&<-C>&>$%%;!.H&34@DBH;C@>1C%/4E5-4;/.-+3@BF7")
@r4598
GAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATNCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCNAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTG
+
;#!,:&>=1:7H@F;,+0H%B6D($9A6=05304F0=>>#*#+'7.3B$<,:E-G3!CB/'!?BG,76G!BDG21%5.-0-A?&E2.4!/-/&@4A666+5;%.0E,<H"<0$5>F)>1C"?A/3+1+74&6%,)>D!?>?<*
@r4599
TCNTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATT
+
(&)=5>+!-F=17E7:.-D4@0*4/+$01A$3$:(-7,.4+0@&+,;=DA+*/">'>;B#7(9#%$?B90'0-9FG="*%+)@(G>=F&E6EE'1/!93C'D<CD66
@r4600
GACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGNTTACTGTTGCGCCTGNTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCC
+
28E&*A22'A-45$F>3)22+AA6;H22''.5!/++>6>6@0:3-8*404'B'A09C<*(5/(4;2"H'HC091-5,-)A<:5&AAHA9?62',=;%8B=H#"C+"1!/-C&CBC:G;?#.0$3$-/9<#%$.=%=.4A-""3;9A7#5D&C!<<BE(:4'?2:C<0-HF)!G/8C$#)%9.7E(AC*@%"B=94*@"'$.BC#
@r4601
TGNNCTNCCGGNANTNTTGGGGGNNNTGCNNNCCNNATGNAGTATNGANCNNNNNGGNANNANAANANANNCA
+
$$"!#$#$##"!#"$""$!$#"$$!"#"$!""##!!!!##!$!"$!"#$"#"!##"!!""#"!#"$$!$#"!$
@r4602
TGGTCAGACNAAGCGAGACTGGCTCTGGAGTGGNAAGCGAGATGGGGAGACAGGGCTGCATGNTAAATGTCGTTAGTTTCTCCGGTGNCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAAGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGNACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGNGTTATACCGCTCACCGTATTGCAGGTTGATAGCAACCCGGAGCTTGGACAGC
+
:="0(<!"$$F9;@7,88-D$!4,$-<;<2<&;)-<H4<)G07>.(.D@D@C1;('=:<5$#B.:$B?)8):6H,";,?.*E<#;C:C3#@"(*0E#*?7A@BE4G'6->&C&/1;GH8>G&7F=E/GB-4B283:003G?#EC($$CG>E(4)6.7:G.<$B/4):9E1(C46D:8'?B4-(+CE2<CFH#%65D;4B6;8,)A(/8F@217GH-%(/=H13@D3C9'>H%C,A&;G%%C%2C?7<#2>,9B:7".F?:B;6B7;H%#>4#5"*
@r4603
TCTGCAAAAAAGTGNGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCNTCCGAGCGTTTATTA
+
:F90H5&$3:2&=FAB@!0G.#='%G'D0G9@?"@"<F626=+.09:!F1/"3?/,/E=$$&'DA03H70(C:"61#
@r4604
TGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAG
+
2(42F%AF+)+G>7+$&976#$".GC$(*<@3'8.DC99*/?419$G<!;HD">40#'>!BC2!=(?F%&C2%&7#'=(A$*=D)7C2>13"H!*F*H:/HA)2A1A68;2"1GC&@#F7;7,94A9!5E%1C1:3,52#),:@&*$B9AH20$@G4+<BE%,@'%B%8E&00<0,13F&:67*E"9#B+4<$*>##"##),&#<+=1;3
@r4605
TGACCCCACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCAT
+
D7G(&=.%A<E5**9,5&,2"4@784&4-H9$/;5=;G$?'H85!:*<@1(1+:%=@/.%
@r4606
TCGCCTCCGACGTCTCACCGAGCGTGGTGTTNACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGATCTTTTCG
+
.&;'*-1#;:G9-;/A:9;0!-;&>>?FG85@./38&'F4,3GCB%5@0$0F/)=#!5(CA"!,F6+)7%C'<#(4B+F<CD#!%&427?:09-0:71B%E",%%-2)/)21:.>6("#4)-184<270507G.F25.FH$%+"G@+C<"?%.,$421&G#DA7/C;':?-;?%"C*>(>96:+B97@DA'8)4+FHHG=)*@2-**9D"!,5=1&>(
@r4607
NNCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTNGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAAAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGC
+
'#3=.$!,:($F/.,37!$.#0%1H-'+*6,=-42!$1D!/:>9"*H>:@3>(HF-:E4":@!CD;)/%B+02:3$C##7+&9@FG)*6$*BA9H!A),$F99H(.#3B(4?G&2A1
@r4608
GAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGAC
+
0)B2CD:#!6B>,?37&8CH@'CC%D$$!9/;>/4-)A/.?<>F249#8(+@A16'A0=8(8E20C-&.BH:
@r4609
CGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCA
+
2+H%+-#D5=+'45-DH>DD&#G/-EA6>=D?"6%AF$,)/H.,+(B2:<&:E?*>+/E&89@%D$3?HD
@r4610
GTTATGTTCAAATGATCCGGTTTTCAGGAACATCGCTGACT
+
;=:7:E??FF@@F$8<35E/'6+HD-B'70/F7ED3@5#1B
@r4611
NGCANATNTTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGA
+
$)!'$*%'++#())("')$&$$%%$!*$"#(#$%)&&)''&+!"#"$+$#$!''%+$)%
@r4612
CTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCT
+
,>4)"B?,7/C5#9:6A;E%!+1AE:2D07?*,!E-@*B!?-?%.>AG>0."""3;25.+;)
@r4613
CCNGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTT
+
#@0.*#F/*D3@,$E!*=,$.3$7;';H/D?8=H-D.&</G%.(@1;)&518=>?>,);</C*6"88&+?>>.E<.!H2@D9%FD"!#(F!H;(6G(6-:DD1=FA!;/2>&"8#;'15:-(;9C
@r4614
TTTGATTTCTGCGATCTACGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGACCATGACAGGAAGTTGTTTTNCTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATT
+
%D#<)2,5AA0=8;@B5B4,G-,."H93C?.-E0EG)G@'%!5-9?G5&%)@!?B7=4G7.,#@(=*"G832/5*G76G6#:+2??<83,B0'(*?F+C0@"C,$"=:BD,)@"9$H&C<-=CA)(&%F(3*:=';F.%A!A'H4:F8
@r4615
NCGTTTCTCGCACATTGCAGAATGCGGATTTGTCTTCATTAGAC
+
!66&4F*$89:9)8!6'0?&E%D,<<>7/.D/$()4A>A1.""(
@r4616
GTCGGANANGTTTGCAGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAANCGAACA
+
&''$''")('+%&%#(#)"%$()!")%(&&"+*(''(('('!+%"("))%#")#'&*&*
@r4617
TCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAANA
+
F1-1!67(/5);2:BA74?DHG..G8>=)&B1%%+A,4$H2GG23,08912%;B-3*?21?CH:B5G-9>:F77
@r4618
TTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGNACACTNAATCATGGCTTT
+
/H+7E436:1C)B!'+@H?8""!)//23AC7&+-*>4'9=H2G,96F,D30:*D@21.97/5CG",>*0B@*.F'5,96*!G
@r4619
GCNGAAANACAGGCTGAGCACGGTCTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTANAAGCGGTGCNAGTCGGC
+
G?-4(%&>5A==9FD5>?>-E=%&"E=CC>F4";-95)(05/>GF$;HA>*F.%+?>BF",7/(5GBB9%-B<-B;(B#G6?)B$+5E<7:<!D.E8-/0'&
@r4620
CCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTGCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATNGCAGAAATGGTCGAT
+
=;&':)541:EE%3;'"@8%)H))6@E?8-9:F?GA8/',A>5>?(%(0>A<FG&D@:+@C=$(;.H&?(<0-F;AG=%1#C?CE(6$CBE?C?.:C<,2)C9/-F;.BH?D@2AF.B>.2D:!@AH"6/H2*>@8=7*90-H;)2()*3A3@0<?2H
@r4621
TTACNGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGC
+
%?;==E&-H+&$B+D0D>?&662<->'=,E061.:5?8(:&-$6C$-4""B<-'$6FA+!EE//$)9=4
@r4622
AGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCT
+
F#%.>&!)H-<12'4D>B?288H3;F@0?5;<$5$%";)AA"4!)#
@r4623
TGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACNGTGAAATTACGCTGCCATCCTCC
+
?:@9<-(03G-F$:C/1!;,.=2@H,CB72,@<A9,2CC%#.2557;='(D,.8GA73="#>&%'G;=!@-#)
@r4624
GTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGNCTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGC
+
F-246EG<'@H0D1F:E/BD=00;>$>0A;F&:2<-EC&56+58>G)?51'%<C=2(A<;$7BH/E,=@8+B%D1:'B/;)G!@*+&405:0!=)@/3#/0B1;1@==960E(;9E<'G9*$9&%3@(HA2#;@
@r4625
ANTANNTNTCTAAGTTGACGGANAGNGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGT
+
%()$"!"'&$(!#&"('*$#)(!%*)*&#)+)!&*'#)"+"$!$($$#')$!+&#*)$!#&&&$#$$%#)%!**($")$
@r4626
CGGCTGTGCCGCTGACAACGGCNCCTGATACANCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGT
+
=@@!((-6D-<,F8A3E$E1%!%0=E1+(-4$-HA8%">',.&F"7'F"<;1%8=6D4*GF2''!/%&A1+!,D@;*E8(BC+?:E
@r4627
TACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCCCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGTATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCNACCGACCTCTGNCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCANGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTT
+
19:8=C.-G#)<)&6F,*(:$21-..GHF*";6//%40A@'-+'#''<5&,#%7%!#"1;&8DC#FE'!.*E<DD>)2C@H%1*."7/-CCB<7'%%;?+CH'5475%8%-+1,D#5/9+.2076G(:?,!#()@#D80H::0C(G;A..?,#>/:HA$GAAB<@:BFF=403@>%?=G/,3?6);CDF@;DB:(H$B-15!B:)!H:8=1$E<.8/5'/.="F(9<+41'%/3#(C@)4)>:D6."?F35>58#H*8GC@(9E1*9)%G";C)5('+%4+"@1?>+76;G*A(3*,C!%?+F<,G=8)(3*5C6$:59#-"CF$=G'*G=9&E,
@r4628
CCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAAC
+
43>!8=:?*>0-<>D4698/!)%579@,@%8?H=+A:E7A,*,+;@C4908$A'::$>)7)<;'9:G4/1-:.H!%C
@r4629
AACTCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGNCA
+
')!D#+H3.*/>>8A1=C!7)?=698?EB)919E0:<1*;B6G0)#9)-::9F=,
@r4630
GATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGNACAATCTTTACTACCGCAATCCACTACTTAAGGTGATAAATGGAAGAAGAATTTGAAGAGTTCNAAGAGCATCCTCAGGAT
+
(84;(1&:$C:.(4C@9G,@)*:1*#(A<<*.-%(;.;6#;'>B%'1AGG&C5#)EC07*"F&":&/6>2"!D;<)1+;E*!(/D;3@F18D*%,D+94?=!#570$;/!*@7*EG)FA>-%F/D#F0<,>%4,.@=?,+
@r4631
TCGCCTNGGNNNCGTAAGCAANNCTGNCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGT
+
%%)$(*"(*!"#$$'(&)%#)#!+$*'!*+%+$))++$'%'*('++$#*%'#)$'"*)$'&$((##*!+'$)#'%+*)"$)!"#"+&)#*+#+""%#*'("$*))#""
@r4632
NGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTA
+
%&(E$77D*).4"&%F4$B:2CG)!!F6=(&1'94/=/?4H99>7B0,(!>"26,+?@#.&H<DD#')9/4HC*)$=E;771#:>F28H(<@E?5'#$!DG28-:1CC1A%
@r4633
ACCGATTTCGGTAAGGTAAACCCCGTCTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCT
+
*+(%(&('&''!+'"""')"$+$#'"))&&#%$'#&&%+"($$*!'')#%*$!')((&&&+*
@r4634
TTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCATTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCATTCCGNCGGGTATAGGTTTTATTGATGGCCTCATCCACACG
+
((+#(#)&)'!!#%($(*+%'##)$(!#'*)&!)"%*&'(!$&()+&(&)&*&%)+*&)"##&+*+""*%&&#)+)!&(%+(+*((*(#'*"&$)+")+*))*"*(+''"'%#$*$(('%"(#&$()
@r4635
CGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACNCGCTGG
+
9+%7:05244)#;'*/%1(@;E9@-,B$9@:9&9,0'<?0F#81=&9'(:13;!G#F?:1/%'CHH=0002G685'*.F:E%((&20GD=H9D9?97C"=@-0B=/$+;CA)?F.6'403BD&$
@r4636
TGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACANACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACG
+
4$(>!:/>/H';H#7C3/:D8H$G841&EC-3'H9H:%%9+2*($#3'1G!6#D:23C1@<=(30&77D:97D3$2,?!!119(H97)F"($&#>2;=E*()>A2%DE84*!@0,#F!&?=/H0,'-"'C&9$<E=B/"6F)<,>.2FBB*D34>'/:!H
@r4637
NAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGC
+
#+'!$%$(*'(**#%%#$&$($"&"*$*(++((+"'#%''#))+*(+&$*(
@r4638
GCGCATCTGGCGCACGCCCGGCNATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAG
+
4(-#E290#;?*(G!H:F&88('0*,=0-;2("=0F>,7)8*?,>2:C,&@04E,!0;?C;$!@'&&)%
@r4639
NNTTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAA
+
!*=2(=B';4&=&8$+(*2B+*10&:."0.)2-3>9(HE:!*/,D35F*2'
@r4640
AAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGANCA
+
/53G1++&<:A32=,9=307G*0*B0&5,G&#2H,)5-C3
@r4641
ACAGGNACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATNCNAGCGATG
+
1G68$>;#@5GG-&E&:<*;@)2=,0/A5%3<)3=4H6&"A#0?0GA%-8("F6=>
@r4642
NNNTNNACNNNANNCTANTNGATANNGGAGCCNNCNACTACNNNCNTNNN
+
"$!!"!"$$!##!!$$#!!"#$"$"$$"!$#$"$""!$$#!""!$$#"""
@r4643
GNCCCCCGNNNNNTNAGACNCTTTNATGGCTNNGTGNNANCNNGNCTGCAANNNNNCNGCTTCNTCNTCNCNNNGCANAAACCNNNNCCCTTCCNNNATTNNNNCNCCGGTNNNGTNGNGNTANTTGCNTACNNTCNNGNNANNCNCTGTGNNNGGNAGTNTGGTCANNNTCTGNNAAGNNNGNGCNACNTCNNCNACCNNNCNGCAGCANN
+
#!"!$$!#$!$$!""#""$#"#"$!"$"$"!##"$$#!!$$!"$!$$$$$$$"!"!!!#$$#!$#$!""!"!#""$!!$$$$"$!##"!$#$$#!"$#"#"!""$$#$#!"!!$"#$$!"""###"$$""##$"$"!!!$$!"#$$#$#!!###$$#"#!!$$#$"$"#!!"$#"!$"$!#!#"$$"$!"""!"$"###"!##"$##$##!"
@r4644
CTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACNCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATAACGACAGC
+
F:#A5,A@3'G#(6("9.+G-E3@9A%F:6DF>,#D<366!/;$-25$FH$="-8*4%&7*D&#;C!F9#5:@=9842*,?1CB@90%1,%4A6--%+'@2A@DB#23CH;<2-'G1=E08C-3$$0=@0/"#?E#64"!#+!'3@'%E85'=1=0+13!.:&@=0*-&=('G3-
@r4645
GANNTAGNTNNGNGCGTNNNNCTTCTGTCTGATTTCCGTATGCTTCAACGAGCANGTCTGGAATGGTTTTTACTGAGANCGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTAC
+
!&""*#!%%!%*$"#'*'!!!!%"&+#)+#'$*$++#!(#)&'*&#!!+!%!'&"!")"(#%%"%$)"(%*'"'!("')+%!)(!)*"%)+$"&%&#*#(!+(+"#)&)&'#%+))+)'+!+#!(+$&+%+!(''(!*###(*('"#+)+'*)++&''+)"(%$!+)&''&#"!#'!)"++#&+&)!'*+#!**$*#("#(!%*
@r4646
TAANCNCAANACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGNNATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCT
+
*#*&#&*)+'')'+%"*#+&+*(*$""'&)#("!()&"&#"('&+#$!*"'!#($!!)*++$)+'!*"((*'!!"+*$&%!#!"!((*()+'$+$#)%%+$%#&$!*("%"&('#'(*'"*+!(&)*+%*%%+)+$#"+')&('!%$"")+&*&)&$")+"+!)$%!#)")#$&+*($*(!*&)*'")%$&
@r4647
CTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGCGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAACACAACAATTTTGAATGGAATGATTGGTGCAATCAC
+
1C5&"#C.#$4.9(<=H!@8"2A&/-3E&7!#3,B37#?<D>>F91-FAB<5!<<C;1GCE?>%<:'*"E;H))8E+H%EB:GA%@E)*B6@D0&?F8H-0$A)&8C(G=*)54A96<,&CGEG2B&"ED#).?;A5;7?;$4G=(5,"5=<5F1'0*;'$AA1$&;C"B..F=10;#*@*9>4.,6>E2;G-5&E:$7&,2G,###->E5*+D2>5<F.5BCF
@r4648
TGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACCTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTACATCCAATTG
+
"%1%!;0#%:::@?6F0=8H*DG.&8*,$;7(5%8#%$2.:0:&H:1-.+$6+#<%47>=>0<)2/0+0?*%4F7=GG52%,)#H>'8.5/.<:)#8->?EB:B
@r4649
ATTGCAGATGTGACGCGTCACCTNACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCNC
+
,650?E>#!(HB@:)&C:(9AE5EDAG+H=#0',8*$>GB>0>7C7%*">><9.H-C%)3H$
@r4650
AAGNGNNGCTTNTNGNNANNGATGAAACTGCCNGTCAGGANACCCNTCTCAGCCGGGAAAATGTGCTGACCGGNCATGAAAATGAGNTGGGATCAGC
+
##&))&"$)*"%!'#$%*!"')*)$+%&!'"+#($(#!*)"&%$(!&+%((&')!(#!"!&($*"%!"')!%"&!")$'%)*%*&%"""+"$%#$#&
@r4651
ATAAAGTNCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCNCCTCACGGATGTAGTCG
+
6<;,7=:H0B?#;.H*'B.-@"2"(@)-34D$<FD&*,7='E6/!A3+9#A;#0C5?3.>"17'A1><'!%".3A=81=4-9=-1DH6&,+49<8GG$""<&-G>'C4*$EA:E0B)F/#D:?8:7$*H45688H/?+>><#1&@4D
@r4652
ATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCAGGGTGCACTGTNTATACCAA
+
+:0C4)++D<E%C.3=(!.B#%81)HF%7,5H!H103BA*'%F@4C=C2C-B6%18)2>'7&F$:+,>A$"'/@G7;C=%18E6
@r4653
AAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGG
+
=7-ACD&:@)4>5F971%:(2!0,7B9,#//32C%H"1"B7D.H:D<;F+C7+ABA")"F$83
@r4654
ANTNCCCAGNANNAGNAGNNAACCNANTNGGTNNANNANCANATTGACNTNATCNATTCNNGNNATTTGNNANTNTNCNCN
+
##"$!""!!!""$#$#!"!$"!###"!#!#$"#!#$$"!!!##""#!##$!$##"!#!"!"$"!!""$"#"!#"""!#!$!
@r4655
NAGATNTCCANGNCNTTCCNGNCGNTTNANNNNTCNNNTNCTNANNNCGNATNNCTNANANGGNTNGCAGNCANNGNNTNANNTNNNNANGNANCANCCNCNNNNNGTNNNNT
+
!!$"!$###""$!"!#"!#$#!$#$$$""""!$$!!""$"##!$!!!$$#!!!$$""$"$!!$#"!#""$!#"#!$"!$"!!$#"!"$"!###!$"!#"!"!###!##""#!"
@r4656
CTGCGGGCCTGTCNTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGNCTCCTGGGCAGTCA
+
BDE6&B9#8GH6F4&!7<CF*,+.B49>55!#3E!6A;D<0E-G5,9H3C'5-!>DHD>6:0BD0D)2#8
@r4657
NATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAAT
+
%%F4&(1257397&:0=G1!+*!BFC,D)&C.D76-)<7*.'C!$#31@#4A
@r4658
CCTTATCTGGTTGCNGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAG
+
<%C=GFA(A.;"C4E.<@"6)+E63G>?"+&+0@8%CA2A:#0H9.+.@"=3>*@+?/
@r4659
CTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTNAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGNAGGGATCG
+
.*HD!)E).0<8?9?&G+9):@F/F=$,7E3)3(+$-@,9&8.),:,$B$<%,%F=(27H(G>8)=B7<:;6>GD/E8AA=&FF43%$)0,'8B7=',9*1&F8*.32*8''6@HH1<%#46A80;9F4;4'(A.4*D;'.F.'F:!.H2.;G13/E*/((F%?$5(-#2+-,"77>/7)E#"H=EG%#A+*/
@r4660
GGACAAAATTGAAATCAAATAATGATTTTATTTTGACTNATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTNTTATAATGCCAACTT
+
5A2AA5:H=794H=5&9D2<82H*#*G.H#*-GH.H.'E21*H=C"!'12!=2,56'>H,'=$?&H"A')>*=$.$A!C724.6C+H.+>:(#5>3H
@r4661
CCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGGAAAAGT
+
A#D6*E*2)/C40#*02)<E49=1?82HDA9?EB4'906:#H"1H8=C-/F(&=4:.
@r4662
TGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAA
+
><./,HD!-$;D<<$7*'B>D9E/6'#FB4$'2316'&H!C7E0HC>B/9FE<&H<8@;+5H>:-=F6:?H;#$6AH5(!92?G.;%"(3%(6%B(+"?8
@r4663
GCGTCCGGCGCCTGTTGNTTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATC
+
-H/&*<%4*D4%<AE89.CF",G=B3/#GA;H%""%47-G%%%231GE:/H)5BF>A/;*8:#4C#29E%'/=!!EG.94"+?,?;4H<H+4C#=/59>)72;=F/31/,,6=**,G37"H27"*=!"952F1F)
@r4664
ACATCCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAACCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGA
+
)$($!(#+&(&*"*)*(#'')"(&'$)'*&#(!($%+)$'$"(#'#')&!)*+'#"$(*(+"%!$'+$+&#'#')(%%!('%+$)+'")%'($))+"#)(+**#%*("($$($%%"'&%*)&&)')*+'&'%**"##"$)""'#(*+"!(#"#(*&*$!&%&&)#$#)(!#%*($''*%"#("*!)')+!#')%&#"!(**()!(*"!#&*!%**#"!%#'))!!''&+&(%"%))#%(&*!$#!#($+%)+"!
@r4665
CAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGG
+
7B7H%5(C.:$?+."(!H/'8'H<?1;>?(!H4@3A8H&'$7&%073#52$$F2-@+.5)!E4#H;1<0!=E@@027(F>4;"%#4-@0+21<B.6G#0
@r4666
AACTNCTCCCCGNTGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACT
+
)(**%++)*$*&)&$"'$"'&)&$#%%'%#%%!""+)"$$&"!(((*!%!*!"($+
@r4667
TNNCNTGCGNNANANNTNCNCTCTGTTNNTNNNANNGGNGNNGGGNNNTCNNAANTATNCTTTCNNGNNATCTGNNNCNATNAGCGNCAGNNGCGANNCGCCNNNCCNGNATGCNNNNGTNNTANCTAGACATNNNGNNTNTGNTNNNNNNGNNATNNNANGGACTGTGNNCNCCNNT
+
$!"#$#$#""!"#"!!"!!!!"$#!"#!#!"#!""!#$$$$!"$!""$#"!"!#!#!$#"##$#!##$"$!!"$!""$""$#""#$$$$$"##$!"!""#""!#!###"!###"!!$"!$$!#!!!$#!!$$!!#$"!#$!!##!""""$!$$$"!#!"$!!$#""$"$!"$$##!$"
@r4668
GNNGNNANNNATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACA
+
*!!)'"*%!$+%$%&&"**)'$+#$!'&'&$&"!)(++&)&+$()($""')')(&*%'*#%##*(")#)+$(#*)$&!$*&+$!$%'+!%!+#"&++++
@r4669
TNATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGC
+
/3@7:E41;C?GG=G20=*8@32#C$%4)*A&,),8+(6?5=A>-E83>!?B'5->A.<=48/!4--;=F>>14C5::,G3*785.+F8+D=33;D
@r4670
CTGAAACGACATACATNGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAAT
+
"@+209H*.FHC9;4:C#1@(@FE".5E<H82%!'0%@)'2.8*)/E;<%E,*7634($A9#."F7)A3)(G@,462=F4%'
@r4671
NTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGA
+
!4"@=BDA'=@C"=A!2#:?2G6;.39920"69%*-#H!F'4A%CH<%9+AG?/G#=;:/?03*3AFH>(>--E"A8.=
@r4672
ACCTTTAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTA
+
AB6<@@69";%&?6)<04@HB2#2"8DHFF0H#GE)((D779#3'>D);$8B4.=3B5+!630F<:?!D):3*#$+:CB>?.7@,.0916DA(",*6'04#CDF7D?3&"*#/.(!F8C"'"A:;A>@&-<<1,*CCA1H%;,">;B$!E"GG6*@4C?C'>E!(H+5C*"!6A2%69D6>-+.1D7<#!EA&0GB&;(!$3%@8?F
@r4673
GACATCCCGGCAAGNATGGCACGCCAGTCGGGTCGCCCCACCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCTTNTGTCTGTTCAGGGGCATTATTCACCACAAACTCNTGCATACCAGACAGCCGGTACACCACGTTTNCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGAT
+
7*?H2@#(=>;-EED'BB9/"#:#:>,$:-F;,>"0H>!;(2?-(*5B7(2F'/36E%((3G+.A&DF/&6&#"=7.C"B?$<?'@EF4+<&$0(GFA/4$A6G<2A<G*@@AB"#5*A$BGH>@%@@6'68=E2%?AG:!=!-436@@7(=/G7;'F!3$!@0*3E@0F2:*C675A4-<2.:"$10.,)-BH88@+5#D9>@E:*'/$222G#0801-5G@=EC8&C95GD&:*02F*$)70%/055<1,9B55):4,GC=8&@'C#A+,$<$-48/H>0+02<"<
@r4674
ACTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACC
+
$<#3+=9%33:9+(!-CCA02<$$)269;'>7<'$;:53E8%:
@r4675
CCTTTCTCTGTTTTTGTCCGTGGAATGAACANTGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCCTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCANGCCA
+
9D.A(+%.%4)06E>&/&.;#4#*3+;3-:>!8@>!95E*2?D(<!+B1.7$G8%032@0)H>!/2=0>4-(B/E&*'3,6A7*@;0F975#DE<B:/,AE<;";<G<B%<.5=030?88B$(*!50("(.#+&6@3H!0(%,=,47G-;&>>(#"8"<)D!#A7?=/921%7EA!)C,*6?=C2A=A*#$)?&5!2$@&,**A.+@1=4*29B*+9-9:118<>>8E&F.>FF%E@9#G46G&E:D(
@r4676
TACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTANCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACT
+
<5-@-E'3%#)$())-(H,;E7+9.GH'H*.)&%;>"H;"B:13E34,:%@8<+7B=7(%+&8D)>322;!((0#*218&:95?$D:E"43<"@$:%-*;,4./F294!3#F9(*::5?,+,=%/<5?+H3*=,D&>*
@r4677
TCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTG
+
"46;C-!?%(1/0@%/BH">6(3:F!G1)@#)D*-EFA#(<#$38$/=.#:H+D=>(&"%02!9:G,8%;%#+/%9?'C3(<A4%FB86CGHB9$+G=:7#A&@4-FEE3FE?$.8.6H5+A*H631;GE/9'7
@r4678
TNGCATCCCTCAAAACGAGGGAAAATCCCCTAAAANGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTGTCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGANAAAAGAAAAGATTATTCGTCAGAGAATTCTCT
+
!!())$+$#++%%*'#++"!(&*!%$%&*(+)#"+!'$!"!$&!&'#$)!)'"%+!*$)+!'!%!!&"*$&(%)!(*&!()*!+!(%(&!*(&)"#+&())!)!$(!&()')!$"'+#!&+(+)%"(($+%$+*&*#')%'!%(&%'
@r4679
CTTACTGCGAAAGTTTGTTAATGGAAAGGACGCCGCCAAAGTTGCCGACGTTATTGAGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCNTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAANCAGCGCCATCCGTTTCCGTCG
+
$+A*A.?04DF/>/F@<1,%<D!.<$E<*@F!6.>B7B8)H5363+EC:!>:-B8C2@#5C0F1.@6,>+8GE:5?-3FG&>.8,DA41-)),C=5&=H:69+<EF9/)B&"'(-0*B0.%:,EG=/*F.15*39B7+"-15*!.E%1.@F?8.8.?5=5)BG:E<10G&"..=6;&9+0B:FD=1@-=(;,EGDG+>'@%F$)+A)6A(G:GA#%;FH5")B.B4=+/#:+H+
@r4680
TGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTT
+
$A2?4/)AA#B?>EG17;/;!G-&'9-A%+'CC,@<5'69@(>,327,60-/?>)4A%!")AC=E&"?)-18F(
@r4681
GNNANNGNCCNATNNCTNNANGCTNNCNNCNNNAACGNCNNGAGNAAGGANTTNCNTCNNNCNGCNCTCANNGTNANNACNNTCNNTNNNNNNNA
+
"!"!#!#"!!!$"!$!""!"!###!#!!$#!"#!##"#"!""#"!"$#"$!"!#"!""""##!$$##!#"!$#!!$"!#""#$#!"$!!!$!"!$
@r4682
AATCAAGAGAAATCACATTTCAGCAATACAGGGAAAANCTTGCTAAAGCAGGAGTTTTCCGATG
+
7(;3=DC,A;!"#*AE#5B7718CB8%1%HE+<!&.1;F)8@";"1:,($E:"'#>E;B#,4E4
@r4683
TGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGANCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTCCGACCACTGGATGATATGGGCGCAGATAGCACATGCAG
+
$8&.8>!A$+A*,@#%'B*2/AGEH;98;%?1#%(.8B12++%'/7A#B8107=>/=24>5'A0E:-?+04&+#E>A!/HB;?##"5:<B>,+(/8@B4HC%-F<=#0'5+'8H(A)D5D&,"CFD1%"EA,BH?99
@r4684
NNGNTTAATTTGATGCCCTTTTTCAGGGCTNGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTATGTTACTCGGGAAGGGCTTTA
+
$!'&#+&!$&!$$+"+*%"&'+$%*(*+('+((!!&"+*"**$#+*(+)"+$(#*&'&"!!$$'"%()')+#')#')!""&*%%$'"##"+$)$"#
@r4685
CATCATTTCCCGCTTTTGTGAAAGGGATGCGGCTCACGTATTAAATTCTTCGTCT
+
09!3D:49*9=DG76/94,ED'<*-8C07.;?(F*EG5,)87:@H7%H>!)<5.*
@r4686
CGTAAGCGTGAANGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCT
+
G7"#:$E4E(3*'.,=!0#&%4F&#G'=/3,=!C6%0,+".4@1B5%6@D-%3A/7D2;3H&E9H47:@1E8!AD%B2+%;'C:8+E(G62):;$4'6*6>!3.)?*+'DA;"&'313032E7HHF88:,D/=)-7&2"F)8:$::9-#-,;.:%4,:;G$..<H-D(-5>*-2:B(.?FB7(7D*E:3(40H+F<$B:?9:D
@r4687
GCCAAAACAGAGCTGTGGGGGAGAGTTGNCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAANTTGGGTAAATTTGACTCAACG
+
H3HA:/#8",=%()%%*%1=<2/;&C?H+G70,.+*5!$(+G)-5(3.*"6';F>&F-,'!+=C'.=!:!E:?(F,@69-%0%)G<.6%F;((3-&01',2=5#@!F/EH:&$>G9F7),G*;C&D'E$6/=52*G(G@<=0<?!&4B<4*1C8)6287FF7#4<>-<).D!)+C36/+G:-F44C!-+#!A.@F2?9,)+'6H</.<''*<5"F$F9!**%&&8".A+66?>E(F$48)='010)),>C7)<*A4>2!)-93*F#///!45A>*?H7A)5$4:$!C?@A4&31>(&*G;,A3=AC==7529:H2
@r4688
GATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTNTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCNGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCTCCCTTTCAGCGGCGACGGTTAACGGCAGG
+
(5)$%?1-<)8:,&?7=%#+2*0.C:,&D7C78@?!"4$./-A$(7//0C#;8=*B$C+"*-"-&%?'E-!GBB.@%!=$E991D$AB887#G>4.$?B0'G?8<ED<>!FF(G0BB0>('E?!;D&1&&HG'$7H5!,'!H6B(>"<*<B,,1*$/:-C+7",DGC?F(B>'!'41&6-2'G2)A;'5*%16%,.GD>3%G"0E76@/BHD*2B>@:D07(<EF98/5;*5E)B-=-0:/:*%>D+..EEGG2,9HA5!%A7B65/'('3&:/F<:,)-%=-1
@r4689
CTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATNCCTTTTAAATTTTGGCTTAATGACTATATCCA
+
F30A>8"F(68B-?;+*8A$/8:?#?%E<"<%(=-)H!7=C;F@=DB"9*-2.=!>A+(H@C#7$87&F*"/!#+.DF2F?@$H6*)
@r4690
AGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCA
+
.$./!D=61F%,)0:D&@1,8>%5C'6D2$,H-+),?3HF$&(@*$/#<AH)8<80E),H:)-1A;/5E5B"7>87!.7*:?+0=1H0B;#9CA
@r4691
TGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCC
+
;0F;19A*.5=7;DG;7:C23-)?E#3A,+*2A'>*<.<FH;AD&2-(;2B-2
@r4692
GTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGGATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGT
+
HG'.&H%)C#'0"+D4EG!*=F(@"93+'H!.181<=:*")=-::=/-%)2#?3;))>"10C*"CB#F/$6-(95'E=/@%1#7%=@"CC<&!/--64<9?0(C!,9-#<+E-.7B!4!&3G!-"9-(<(#$@:7A04FD,:C"#H-$E5H+4+5(<<-#-=C8F(#">:2A>>8GD9$"@)17,0E<581'B/&=71'?G&*/>#53H-*"1&6C80$94.?&8-2;581??(-'!G12;:B'.HF-#B69C+:!1&2C+1!57,5C(>&63:CC9&DF5;,6'=4()$,,=7,''0C23D2""#%8-?F5)D,$>:1G3>6#2=/6<;G+)B!87#G'#=();04H
@r4693
CTNAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATT
+
"##+*("#!+))&+(%%#&"%'*%"*'!'+'++(!!()"%*)"($*#'#)***'"
@r4694
ACCCTCGTATCACATGGAAGGTTTTAACAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCAC
+
%5=G5<0D+;FHB'&>#>E?863&-0:;0&@'0;<A@.FD)!>'<F6!EH$</9/?*(6D&!BH*B&B@486=H#D%<4BF&('=&>&1,#.$H8"2;2#82**C@3(?6!A3-80)##5E@27.70A)
@r4695
AGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGNTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAG
+
9@!D-!'4<./=@@6-$G<5&?#)#=./+>+C4@H9/FD*/<?G?4$?5H&,$%D+F;'E21H6'(B88.'!-&<:6F-*,%'5-17'*'G6E1&54#B.BC)65A49;3EB&GG5%=C02.+:&97-'/<<+9G6*HH())&0*E,9;B'#><,1-)E%4%B@(,>!2&=E%6,02;-2%('>4FGD"&-*./@C36;'(A5&=+-1H>"-%2:%*%F
@r4696
GCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACCAATGAATTCAGCACAGACAGTGGCT
+
@%#CG3+'E177==>F0$;A(!HD9D$>262/3CC(F5H727"8-3)E*0B(?HFB/%.:$F:F27C8'!44C@B(EB
@r4697
TGAAGCNGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTG
+
8<',&45&?)E))3+<$<*AG0A=)*8G%31<:&3"B3;2&
@r4698
CTCATAACNGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGANAAGAAGTCAGCCGCGTCGTTTGACATCACTGCTATCTNCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGT
+
$,5&;"CE(9G8C2GE<&B+*:0'?F(H9,G/$+6")D5@&G?*-%@*AC(*)6G:G*98C2/<43)A7-#GD+66?47#);#<.DH1HH*C:#=7C2D1*-G6H9&(&%B6-$#,7-E7'".(%4))$<D7=.2698&AC<$$63)#91C0/?9*+DD1$&3$*G"H</G7,="2=5G4'1&>!D&?E/58!!'1
@r4699
ATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGG
+
=)1@@&4)2G,C/3%&4%6<H?3A=F?*8=BH&57=2'8%8;A+6:!@5&.
@r4700
GACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAAAGTATAACTGCTGTAACTCTCTTGGCA
+
+#)+)+++'(*'!+)$$!+%#$)$)!+)*&%#()#*#$!$%$*)+$!'$((*!"$"*&)&#*)!*#$$&&*&'"%%&!(+##$&%&*&!"(+'$($
@r4701
CATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATC
+
(,4C%4$B&>;#>=@"=@0?E:788F',@%!F(,F0DD6;=,
@r4702
AGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCG
+
A?H1D,-%E:7%7$%-0<%(5B,0&B06@:&6B).?/4/+?*?7@*54<;2:F?5#7<H'=1*
@r4703
CTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTC
+
=46@@0<D(H&+84;$5?$-E"08E+*!>.@8BA(C8B0H
@r4704
NCCCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATNCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGNGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTG
+
##C6#@?/,B"+=/!22"@=$;19"7?HEA>?#@H5=D&->A05,.+0;=<F?20=D+*&%%C#<,'1EHB=5G6)1!:1F;08F2=!D<*2*H((GA:>25<494F9EB1E5":.:+>?HD+<.0#4",5651)'26-;4.(A,-0%-+68#;,:9G5'=+C-+F5C=E'9941AH-&>E;.7)BH4?&D8:0G'A%:48)-"E:=>%%7BC-D019B?+%&B;:"?H%:'6#-GC8!0%D(HEB=*%ED7:)?$=).>D':4,"H,;1369@)/$3.?->,4D&$)<'3B>0"2;8E0,+)0?:/;(#2B;A7CA5+)%8)5>.A!51?F$@D!49!35#F)B#;5/2BB7<@-*+//+#E!/EF1*H+=)
@r4705
CACCGTGACCGATGACCATNCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGNAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAG
+
E?6$5:%C"/3C,;!95%6CE:-.5G76>"ADC!!/.E-24E=F?;-<,*G"&F3#*<4=D.?A".='+).:$D**?2!#;<>#CFB>"99:-$1(G+F*?+6AF<?33<,":#27
@r4706
AATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTT
+
C0)%<H=04/+=+4<@$80BHC:'<BEE@)9%3',0.A&1*!+@1@202+<<?F,12*)/5<>%':8+EC752C7C9(7+?05++&*88.)$,:<;E!H#7F9A5@&"9!&,/#4.H:%
@r4707
TTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGANCACCACGA
+
&2C@?<=5/H30#<3)3H2!4&*#E(EE-F1!-=7214*26>,77&D/,*C!1HEBE@7#D3##<>$A>%C+:,B1%0HD6DD,-*)$(0G.BC
@r4708
ATGAGAGAAACCAGGTATGACNACCACGGAATGCATTTTTCTGGCAGCNGGCTTCATATTCTGAGTGCGTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCNGAAATCAAACAAAGCCAGACA
+
5FFE#G0/,E:+>F$-3F*>15+F,'/$8,12G',0#0&0/-0>"!A%?CD%0(DF13C2'<4-4.0(A53A1(,"?4.,(:(FH6$*1>''6DD7(5G>D3F5EGF:H:12-%:!C5;/@70B',:3?"A1'>-(1B-HG/F8!B/F>1"C740&!2F72(.)&#<57-9
@r4709
ACGTTCACGCCGTATCCGCTCAATANTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTTACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTAGCTGAATAAACNCGCNGGGAATACGACGGTTACCCACCNCAAGCACGCTGCCGCCAACCTTTCA
+
@/8%4B&!;E4G0":3B@EH9E@#D<7C7&=@3.G#$#D&!#"=G+!(2=/C+-,9FEG+A:448H)*/)F8<F&.>!+GB2@:EC*;60<15>!&&!:5)0&@H65G-,*#:B%!:G8E(/1G$,#<;2@#(0?')3&:D%D,+/$&=3+;6;"!GA<E3'1<-G!F4<-0+>23*)%EGC8C'4$*!+=B,=?,A%:+B/<;
@r4710
ACTCCTTCGGCGGGATGACCCCCATGTTCAGGGGGCTTGCCGGTNCGATCACCCTGCCGATGGT
+
?#0C8G$:2<:-4<;.%F?1?B35A.EG<:F>."=D?F18EF.@*?C(A0>.?D@--'-E=/4<
@r4711
GTCCATGACGAAAGATGAACTGATTGCCCNTCTCCGCTCGCNGGGTGAACAACTGAACCGTGATGTC
+
.'=)G="8)562%;2C!B.<$0F69G17(?B%77>H%?#D*$76==+)"/&(C>FB+EH,'1#;:!5
@r4712
TACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTNGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACT
+
$4+#)'A'&8C6&G490>C%,5%;AF.7;3$B@2B76;(HA(A%)"*DF=9C0+5F"4*D+=('G*'B>9BB$H)<FE9,E'),(56<$+;$6736GCE&4(4&:8D)76/".!A)!(2H9,FA,@3=$02-(FC00%B4%;9E&>#29::B608",3@0A*/@2(7.+8G1B!C?5:F+?<*DC64@7G7G5#FB0E3?$*6+8
@r4713
CCCCATCACTTTCCGTACNAGAAAAATGACGCCTGACTCTGGCCATCTGCNCNTCAAATCTGGCCGCATCCAGACTCAAATCA
+
%*!+'+*($%!"($('#($)''+*(#(*#*(%!$(*!&+'&%%#%#+(&&"*)%!'')$!'"&&*#)'+#*'*$%')(%**'*
@r4714
GAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTC
+
?3"<-''"=%6C1)19B$'0*5%.8)9(?@244.9(0)2=.&FA,A-#%;/;8:*??7D()%?#:(4EG=8
@r4715
TNTCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGT
+
'!*$(+("%+((**%#(*+''%&+*)#$*$'($('&$!%!#)#$%($(($&"&%#+*&)(+$%$$)"$!""&$))+!%*)
@r4716
NNNTNNANNAGNCTACNANNNCGNNGTTTTTNNNNAGNNAANCNNNNN
+
!!$$!"$"!"$"$""$$!!!!"!!!##$#""$#!$#"##$$"#!""#!
@r4717
CTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTNCCATTGCCCGCNCCGATGAAACGATACGCGGTTACATGGGAACGTCAG
+
4E=*AD9?-1*,>C/D0>65F3:=!8?--6#3'H3**G2=(('&5=D"'<C02H4D?,8=:<%9DD>59D@B:"'$9/!"'/9:E?9);==#D*:AF246+B@)!=!?:8&56=:&;9/6D1.:!1(-+A.H-*E$**;%!:6
@r4718
TTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAA
+
5-5:/=<*#G;5)G@$!029,0!.62A23(;4))93:%"G@9:F.72%+673+/#E9(!+#G(D#/+:E03*A.4@?13=C=/H
@r4719
TTGATATTTATATCATTTTACGTTTCTCGTTCAGNTTTTTTANACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGCC
+
0/":DDA4:F%)64)-8C?&-139A5)5;&B//"1;B?C9,E?;%F;$G2.E.*9C+8F!9.)D=A,.?;0-<+D8"!('+C@/<=/6G&11E*/.0>&D/2(E#:<3+
@r4720
TAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTAT
+
DG15?-.C7,&D.3CG?6&(($C3-/C)('C9=?.)7B)C"#5@F*@99D.:@E+0>@?E+!E.<C;D!E9!$*>?/"DB(192$".;E)8/2<>->
@r4721
NAATNNNNGTTGTTCCGNTGTGGGGAAAGTTTTNGATAGTCAGTGGCCTGAAGATACGTTTGGCTGATCGGCAAGGTGTTC
+
&&("%%%%+)()()"&)*&')#!"#%"##!*+""&)#(*)!"+$&"!*!%""'&'(#$&'&$+%"!')"#*+*+"!((%!)
@r4722
GGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTC
+
2?9):B,0B'G'>0$0#C%4E#BH?+#;<'@>(0&>,."8$)?*-,=;2'0-42")H+=;
@r4723
GAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCA
+
*(64C>C"%A.826%.,,0G>5/3F8)B2?.7!/(:D*G=@&'6;/-;;.%#%G3E+A>9)7/)7B=?F6),A%89"4:B51BBAB':9@?+'+5#.88-<7%-#!"A?+;*>9(?1G>5D;7?A.@9.7427!EA->*$?4.!E1@A301??@2"-7+%(;&F16<)14DA:0/>2!
@r4724
CAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGANTTTGCTGTTTCAA
+
$30<D-/&8&4%%+!*""G;@&6%;;74D0D*;2#=A(>EG3;)D.-;>.3H5/C6C"18*1;D8-H-8"5-9DF/5=
@r4725
GAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTNGTT
+
?!B"29#$@"$5F&4&&//#%<8A%*3",C0)/5-&0"DAG0F1<?>C4>@0;5$B%!>:A;A34*0='"42>64A&HB&;8)>8'52:?.%%25=5%%!E
@r4726
TCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTNAATACCGACTCAATAAACATGGCTCTGTATTAA
+
"(*+&%)('!""&)*%'()+&*#*$$%")+*%'"&*&"!*)'(""$("!*%&'(*())+**&(&")$!)$)(#$($$*!*$%"&&$((!%*%"$('($!'"()$&+!**($%
@r4727
CTGGCCAGNNNTNCNTGGCGGGNGGACGTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAG
+
%('(##''""*$'%$%*%&$(&(%%*!'*)+*$('*"#+""'&'&#!#!%&"*)#'&$%'*!)&+#&(*)*#)'"!+#%"'"(#%!%'()
@r4728
TCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGAGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACG
+
7=3"%=@+98E05.%'"&@?932BH$;!F6;6A>44#HD%7"250=E42G)H4$B5=:A<'=65H@,''5?H',3;3EEC&C('2"/6?*-3B79
@r4729
GCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGCAACGGCGTTTC
+
39?+D2&)5:4+,->24)>'+D#+:<'AA?%E/H':.H=):--?9(-3%?D:!:5'=?
@r4730
TGATCAGTCAACCACCAGGGAATAATCCNTCATATTATTATCGTGCTTCACCAA
+
:A.>C/?8?04."*)5/BD4#F;G)+9+:(=:1"$#$/1*)<,8@482)'(39G
@r4731
ATTTTTCGCCGCCGCCATAAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATTTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATC
+
!$B@"+#9(0C"!?#E0G"64F'F91F>6(G-2<4/@D)@!>&.>67#?8>HAF7><;+?<;1'+&'&E;*-'/#$/(/C)AE+G7/%(08&00G#41":GH84-6D5=?@#/->6+G34@:AA)AC37C-?@,)4)=G)1&8"7=!,+D**&9?@.F+&$"CD@"C=(>&
@r4732
CATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAA
+
&$)9AG#%HC?"<8E'669?'+%2+F-#@*GE),D+=C7&/F12;:":!A!("B2+9&.*/
@r4733
GGGTGNCCCCACGCGCATTTCCCCGTACAGANCAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGT
+
)#)&)$')++(+%+(%&'!'+"(#)&**%%!#'&)$$+(%+%&+!$)(')!*!$!&$)$'#!)&(%+#!%+!&*!%'(*%(&!%!%
@r4734
GGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCANTGATTAGCGAATGCAGGGTGAAAC
+
>30-">>E+4%7,#$$$.5H*$.=83.=-1>.0F.5;*31@7<-F5#<1D4#*4GE/4#;0>+,!#8F@'@(BC>=A'@FD202C!29A8<F@:$0#@'0E-=D<=#5%(!?1-+/(!$6D!!6-%3+A'=H1:9"&7?@!%,C.814*CC%:2<*-B<('<((7%61&E?C<>:3>4D,G*)G>84EF/#.*8"?!1.A3!1940;%B:G<BE$C&,>CBA?/E1.1##%&*(4-@15
@r4735
TTGAGAANGAAGATATCNTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGNTAACTGCTTATT
+
*:7CED4:+:<*G"01H->5C=?5#,+A'$-,6EB%?G65<#21-G6H>DFH>#(H%#FE4H;::.*2)+,?"G@F?6&E+$
@r4736
AAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCNTGACCATTTCCATCATTCCAGTCGAACTCACACA
+
<!&7:G=5.BDCG<5.)'G;B:,)5F#@E.76>G4/.4<2#+D+(D/-1>);%EB$;.4$<82.6!43%&A+%6#:&5+$F;/8,+&"&,D5A0&G/5*/;/%(D2"8'19=1)2/78-'?FE9B#*@.2=563A@A&</0&BA,B(
@r4737
CGGATTGAGTGCGAAAGCGCCTNCAATGACCCCGCTGATGCTGGA
+
/5.35;/#-02?%D=/$>B:(1G!9=#:F5=43B7F?6#;1E05E
@r4738
TAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGC
+
>/-A$D/$'H(,@B<!?'+)?FE-?'GHC?C:&3802+23.CB"1#$%>(+#/A221*&&.?/11>;AC3?3*.56"@C
@r4739
TCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTNCGA
+
4<D3E)E>/,&6-3%B!A6.DH?/G-6/4)B??*!3!"='/G!>+FD*/9''.+03/AF!((&=<'7F,12!
@r4740
NCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGA
+
!@79"6"/B@>-+-&@7>G,=#B+0?('B+BC5;18!%F+EG<'**B#F4F"C/CCF/B2;9:.@(#A4F4CF>
@r4741
TTACGTGACGGATGGAAACGCCTTATCGACATANTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTNAATTCA
+
#C!6B31>;B76>,:&3*321=B28321+&A1H@99G4>-@&E69=D,F<**F0<,D?.>E<.20:5$!.A,*!"$?1:,)90=>AF<1!*>A*@
@r4742
TGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTC
+
9"'.-6$)*<:.)+B>%E<H20C?-EG?H<-9&%150%-?+(8!+;GD@D<+C2-0*6?5+*3
@r4743
TTCNCCANTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATCCGNCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCG
+
&F!?9AD#G%$!+#??,$0+-A("D<"D>D>.EBG0A#$9/(D56A:2"!4"99AF;>=(D-;EF/)6.D34DH".",+=-E<8"&C@*>A&8?;>75<F6E<?0H+)"(19G@$>"EB@?C>1@((832!1EG"=9&%'4)E81D#=('7&&7+%<4%"%F1'-1+1G,'A"@A5)9
@r4744
CCGTCCAGCGACATTCTTCCTCGGTACATAATCGCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACANGCTGCAATCCCTCCTCATCTTTGCA
+
+(*("($(")+'(%*&!$(($"$%"%)$&%%$%)#!(%!&)+#'(%'#"'%"$($"')&#'!**!'')$')%)$*")!#)#+$!'#*&!!)&"))#&#!!()%+$#($!%$#%$'(##*%'&
@r4745
CACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGT
+
984,)?.;&?6$>",.94@@%E46#.>HB0&&26.7<563D9"92&'D&;37;=A<#7=<F6<(F9="79C).)(C"!AF??<+D5CD
@r4746
GGTTGCCCGNGAGACAAAGGTACGCCGGAAACTGGTAAAGGA
+
7%;/B1/3*/3@6<7F/&/5'5>8?,&FE#374-A!3>+)<*
@r4747
NGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGG
+
(')++#*%*$(#*'&+''%&&%*!#$&*''&#)'$"!*!'(!&""*'(#!&$*$#&#%)#*)$$!%%)&+)'%'**$&)&#$!(!)'%++"(!#)#
@r4748
TATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACNAGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGT
+
:*6>?8>,2G6:DFA"8+!=:FC8:&<*.-6.C#C>'+15@BGC4$$4C-!72E25=7*@@E#,$)'8<'F11.+&+C(,/1<E-@FGE)7G>7007D((3.)%0#>E5!B#G9#
@r4749
CACTCTCAATGGTGGCGNCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTNATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGNACGA
+
A9%@H,F=2CG-2(F-/0,?<CAE)9#%7&:072--D%>&")F(FEE&#8E2<.'*6;"2;.+'3:6='#!46&!<;9GF@B=,?<G35@5,%&F.5&6:/?.<2H5631+'FA5H*;(FGG*?$%538F%DF1F&##F*,8FB,H.2B8>#9+/?!D$B
@r4750
CNATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCNTTGTTTTCCAACTATATAATTTGACCAGAGAACACGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTC
+
5D;7(GG8F>='A?+@:F%6,F2-,3@,BB=(;FD1"1,;%D$&@3)#3'?1GH;0A&.#-D!%H5*::H*!/%)<D)9+;0.<HC7;!.4!$)A1)'<5-<1F">C&F/:H2>E/:'!%
@r4751
ATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCATG
+
$/(48(&8,8-2<@+')8/F8?'AHFB*/B#9E!'GB%C$7D8.%B<<0/
@r4752
AGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCC
+
11.'4*6@E6=?9)(&&52!=D3'#8#1$$.*)<105--+%D4?=5!:'@,D$D>/6(#-H
@r4753
GTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTAT
+
36.&!(81:>:A;80A=(331'B@6=0G0(3.8'8(7</4!7<12F=14'>"!#F15/6/#;DE9*,16(@1".9E38;(A+=02/9H94F#;@*&5$BF:!&96D.4'$"F/6'%4==E4>)>9934;.FGH01?,#,*+0F-=!9E(DH9"?8(*<@.=0!?E)/>A/66
@r4754
TGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATANTGGNCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGAT
+
G+1EE?)7)0F6BDB08+=3:/>.@%404EGG+=(23/$3&6#?,2"84DE@)$260"C!@C"+-<$'$F-"<A.A14*?$64$#*</90F"D<BF)A4:6/&@?A5)C>?A1-<D%:&8*@9'EGC%GA*D@)GB6-8)/(5!275A&C)C0>>04,"&C41/);:<D$7/FC4?=4H@B8E+H!AA7*!,B%>$$:3E$!4?CA2&&G=
@r4755
TTATGTCGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGNAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCAGTGTAGAGCTATCCCTTC
+
'))(#+%(**%#$)+*+(*+#%""!#'#%*"$($''#"&)')"*")!%!)($$%%+"!"#*&&&)&'"&%#*)%#*$!#&%$&!'#+&%"%&$)$+%"'!#)*+(
@r4756
GGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGNCAGCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAG
+
-72:9.5=*H><D!1,(@7>+/4@@11:(B-0?)<E='1E3.&.),08(6FA33H$;!;2!'D*4-.,@@;G7&05F5#2#9$=&%3/-1EE#F:<G%DD5BE#:5067-;:1&@?=-,#=A-H.9$)21:4AD&CB(1%57B69<;?+@C15D12C+
@r4757
CNNNNAACGAAANGNCCGGGAAATANCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATT
+
&&!$##("%#&')%!))+#'%#"'#!*+"%!($%!$)!$'")$*'$"(+$*($+''+"(#&%!#"((#!"&(%(*$'!+%"'*&(*$+)"&(+")%(+!+(+$*$%)%*!)*(**"!((%($##+$()+&!#)!!!"((&#("'%#''(
@r4758
CGANGNATCTACNCNNNCGGGNGANGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGCAGTGGCGGCCTCTGACGCTTTCGTCG
+
$&%!($"!$*#'")#$!'*)%$""&*&+(%)#"'#*))')#))*%+"$%&()%"(%)$!+*'))"$%###"&($&(**"%&)&!+##"%"$*$)"%()*#$()%!+*)$!)"$
@r4759
ACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAG
+
+)84#6*2B<3<A>$1H?69#"<FG@=.;'-G.&'50;B1$(0F?6=&A+/,?E!!!6$&
@r4760
GGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACC
+
<<<@F,BB;-.*'FD!2<2$<#@<=::CH4+"98H/+@0#(;*G&H4<06>.)16*,@!9.!;+0AA90/D!DD:+:?@8C,*#'0?<>4-D->#8'=&+@%>DF0B*)2@EA#/?G0+D')@>)C
@r4761
ATNATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTTTCC
+
))!+$+#"'*$"!!&*$&&)&)($$#$"+'"#%+%""++"$$+%+)$((!+$#&%)+!''*'*$"""'"#"!*+*(+!"(#*"+#&*!'&!+&%#!)+'"("!+
@r4762
TNGANNCCNNACNNANTATGNANCNNNANAANNNTNNNNNNANGANNNGCTCNNGCNCACNCTGNNCNNNCGNGNGGNNAGTNTGNANNNGANNGNCNNNTACTAAGNNNNNNN
+
#"#$!$$####!!""!$$#$$$$#"$!$!$!!!#$#!"#!!"$""$##$$!"#!$"!"$$$$$"!""$#"$!!$!""#!#$"$#!"##"!$$#!#!$##!!#$$""!!!!##$#
@r4763
GAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGNACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCT
+
<0#"C)+C6%0===68.B/?(/C,3!.)+;-/&E%%8)@8!@<B04H*'(B0%%'17A(B)-"1<-C9.EH2C1=C01BC-)B9(5)EC+2EH-4E0.54
@r4764
CTGAATATGTTAATGCGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCG
+
-0;;:%1.*H-&H=+86!@*D@D/A"7B35D+1@F;@!0?>#"#$&89>!G"?'#2C8GB6EA0B&+.D9,'"<2>A:4%*&/=1#A9D+A&H6*$7B(1?/(',:F&A.9DH/B9:H*0?4
@r4765
TGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAAC
+
H/AA'!#1D?7H-'0-$$"F&@128&0<GH$*@F835461EE:12!B&D1D9&$)2FE58@&3?)FA&);",>AFH>GD782:4<B>:EC!&(
@r4766
CNTGTNCAGCGGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGT
+
&&"%&!&(!&*%+''"&"*(&&)('+)'(%*%(!##(#&#%')"$)
@r4767
NCNCTNANCCCCCNGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCG
+
!%!(('')#%''&!+!$#&+&)+$"('!##"!(&)+&+*+(%($')%
@r4768
GTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTA
+
(7=:0?BF9*H99G!)76),)2$E-GD*E%(A,3<361?'"!
@r4769
GCTCACAATAATTGCATGAGTTGNCCATCGATATGGGCAACTCTATCTG
+
'3/*:@7483E4::-8,-&%@=$)*&6=+29>2CC)9-7>),;!5H1;H
@r4770
TTCAAATGCTGCAGCCGCCCNGGCGGGCGGTTTAAGACCGGCTGCACGGC
+
:?<:7(342D%D8-8<0++#0/.CF0D2",D7'2)-?6<2/F*,FG(%";
@r4771
TTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAG
+
4G>DB';@@/8D5&9:0#G+#?CH7AB,/$()<5%(H#=(;:+'+;/="0"80+=8A
@r4772
NCTGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTAT
+
"!9(&1C71B:"<$#%?<;<.-76-:2AC*)85<?#>+;/)9"2=-+>AC9>!CG85$>:2:D>#$"2)B4C&17+#$E6!75((AF=5,!>.-#
@r4773
TCTCTTNTNCCGNNCCGCGNNNGTTCAGCAGACTGAAATCCAGCGGATNCATATCCGGATCGCTGAAAAACAGGNTGAGCATGGTGNTCGTCAGCCCGGAAAAGTGCANATCCAGCAGAACATCATGAAANTAATGGGTACTCTAAAAGCGGTGCCAGTCGGCATACT
+
!'()*&!#$&"(!!"(('*'!$"'&+++$&+*$"'%*+)(&*(&%&#!(%%(+$+%"%&##*%#$*()&(&*%$+(*!*&"$'&"%%+'#*(#(!"*"&#+"$#'$!$"!+&+''+!!&((&)'%)"**#%(+&"&*&+""%($+$+!&$*%((&%+#&$%+#$+&)%
@r4774
GACCTTCCGCTGGANAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTNAGAAAAGTGCG
+
"+(((+((((&%'#%!+%&+*&((+$##(("!&$"'!*!&)"%)"+(*"+*%%$&%*&$""%$$#)
@r4775
GNNANNGGAGCAGGTCNTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCNCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCCAGACGATCCTGAATGTANTAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCNCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTAT
+
(&%$"'(#!+%+%"(&+*#%%$"%%!!"))+"#$"&!!&"&&"+$%&#"$*((#)"&&')#!*%%""(!'++'&((%"$(*)!%)!+&'$$%)'(&##$%#(++$$')$(+%!&+*$"!!#'#"(+$)+)++!!"+&!)*!+!*!(%&(#'+*&'$$+('$#$#%")')(%&!''!$(+&(''+)%"'#%$#$"('"!+())()'')(!+'#$&$'!)&*"+(#')!%!&%*%&!%)
@r4776
GGTNCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCG
+
C:&6;'=2&F!HCF2@<8G(37B+82E&AB8'86##9+6=':"3*+!H<-0B+D1
@r4777
CGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCAT
+
3/F181CG,5(9/:B5*44,9<*2>B<;E4-/$1:!-*+&%E=H>&3$A/+9F&.;,;.C>E+3C3!G$?/G1($4<50G8"=H/.C%H))(-?H992BD1@>-%".2EB,4>8/A&$"=6,,D
@r4778
AACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCAC
+
9$4%6@5*E4:8.A$/?:;4%!H$C1+08>9/&.A1%0*"12)D))6#3&2:$16!;<*(/-/(;".*.33#)"G./F?#$*"B?B8)H#!",1'8@A.<91EG
@r4779
CGCAGATCAGCAGGTGGAAGAGGCACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTT
+
*956-;&8C'4>"G<D4HH*55;;#*A#3%:79%1./<>9A4,4?,?*#G!".%F@'D;;-@
@r4780
CAATANGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAG
+
C6<>936&3D&7=E?966$4&9<D#80>)3@2:(2.4F29"4=E42%16&;76&97H$!)+1-H@18*<EE-95>()GD)!%F69.5=#(2@2#17C.5&687A4B(G=F<91++FF%9*(">"B2(3@D:,
@r4781
GATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTA
+
=-;$HD:&A*8A."-A.C1@',++/*@?=<%6F!E'B18#(B#2H?F&+C636!,$01B-F#)@F1<0-CHB5?,"(=2*!BC<%"1#88+:5'?G298EA.)$9#D6B@6/36F8#C9H8!971F*.)''==%&28,+72,+D,798G+=!1H59+E&!@AD%4G3G#H=9?&F9(7F-/25@G>%=2(4/)
@r4782
GAAATAGCAGAAGTGAGGCCGCATGACGTTCNCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGNTTCATCGCGGATGGAGTGAAAGNGATGCGCTATTAC
+
099G'C%4D!359E+;4@$&ABE#-0=E**C82'F+1))@!/)2(A/:+.=H,%!1)A*(+.&66@E1A!G1$$A@7(@B$2E93)5>8C%",>C1EC(6%?#E2'%A8/G9(.?9F7#;-"54/D81-#/0C7>$7&5#8117:==&D>?60DFC;H*B<!$B-&,F!/G%->;=B@=<:'488/.G7##(%!D!'A@C//A!#AE8>;!5#6<"*+
@r4783
ACTGNAGATTCTTTTGGGATTGGCTTGGGTTTATTTCNGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACAC
+
''%#+$#''&%*+&%*&%"''%'!+"*!&#'(!+#)*''$!&*+"))("$"$+$%!%&#$(#&'%!*+*!$)#!+'+#+'%)+!)&""#$&*"$&")%)')+)"*+**%'"$'*(')!)*'+$*"*&+$$"(*%*+"$('+"
@r4784
CAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTG
+
CE,-HB<28$<.$>-2EE%'')D8*!"05*E..?(BEAC<*5&B321>
@r4785
TNTGTGGGGACAATCCCGCCAGTATCCNAGCAGATACGGGATAGGATATCGACATTTCTGCACNATTNCGGCGGGTACAGGTTTTATTGATGGCCTCATCCACACGCAGTAGTGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGC
+
'"#""&%(&%+(%'%&#(&"+)#$%'%"*&"%&'!'$&($&)&+&&)#)#&+$'&+&#*%*!"!+$"!+*&&+!'&+")&$&"&$'#!%)$)+!(#$"*&"!%+)!'#*%%%"%+!!"*'%()'$(!")+"*+#+!''+''!*""$*))#)+$%&*%)##()'%+$'+!)+*"+!!%*&**$)'!)(+*""%*&'&*
@r4786
GGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCNACTGCACCTGA
+
GG"5*EAC7H24&3C04$<##!'*H#,6#<0(C(,(6G"06HB!4+',+D6*<F21<>8C
@r4787
CCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAG
+
CB3.(-A:.&8G=F6(.$5&+.$G9*)&7)/50>":A&/2.)08'E;3
@r4788
GNCATCCANTTCCTACAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTC
+
)!&*%*''"*'**'"$+!&%*%%+)+%"&(##&'")+&&%$#%#(*&(&#$%*$'&$%&)#'&)!')&$'*"&*$"%!!%#!')')&"*&"+%++)++%%+('&+'&%(&'$*%'))"$'*+&))&$&#()+))#('""('+%)*&$%#'
@r4789
CAGTACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCANTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACAAACGACATTTATCATGCAGCCCTGTCTCCCNATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTNTGACCACTTAACNCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCCAATTCGCCTA
+
)*"06;EB:E.<:(0E01>G/2F*(&:+043A&1%?$+B@43?F+:5&+5E5C,A9%$,+05*@0D4.?H('4%4C!D/;2+:<.&+*>6F6:7)/1-:38'+A.FG>:AG)(AB@A2C&;#4#'7"9.2.2<*%<C%$2"B>+@0,?#6<ED.24'8E#74*)+>&+241&#89";-D2;,BHG"24C"A@)2'.?,9C:E$*(+>!7#%&A%D!*D>:DB%,*4;G0+2B9+"5+%@H6H</2H!+,<->9%5%75(&"<6G0)&2ED&;3G1.->"48$!8ED4-?A2B;::+&;4E28)BD@
@r4790
CNGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGAC
+
'+'&%!&+'&!'+()*+!))!+)$+!+!&&##')&*#$!'!!$*$!$#&)#$"')"%!+)&!$*'++!*%#%+*'#"#%#(+"%&$*$#!!)&+!(&&!&+
@r4791
AAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCC
+
AF)'7F.:$":/*;.&)%0%A;$GCE08,),0&G>'*5$#=B/&@<.5,="3-!5,";)86&D17%6'#@;@>?/..8%#-2#0&2(":F@EF(E,-45@/@-;
@r4792
ATGNCGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCT
+
$'&"+&#)$)*"**&%'$+#"'"(%"*'!*!"+&"&((!"(!
@r4793
CTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGA
+
/<*:#/7&=A2H)(,2:53G):8'6'6"#=:2'99=7"B@3>-84G$.4'+A,<#0+#8=B1?:B;<D/1!(GE=)4$*%<F5"?;4+,':9+"()
@r4794
GATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGG
+
")()%#+'*)%)$"('("$#'#+()&#$#!!'*$$'!(("+!(!&&"+"'%)*'&++'#$(!*&++)#"&&&!$$*#
@r4795
NANACGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTTGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACNAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAA
+
!&!%#*+"")"!()*()$")()$+"**(#(&)))*)&)"*%**'$&(&+!(%$"(%$))$*")$*+*&$!*")(#)*!$#$((+)$+#&#)$%%""*!$'$($$##*!#"+!*)'$&*"&*!&%!('**%**$%!$&(%'&!!*(*!($**'%""++'+&'*%&'")*$($*(*!)&
@r4796
CCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTCCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGG
+
6<F"-'6#EA%.&=888?A?#8H>#$.7.E;3/H@$+),8C+;BB?2&.,;3-G35C2E@"8:"9:!&85'8((;,9>=:$B$'@905+#!.A6,!6<7F45!5"FA1,8*/#E+?F468
@r4797
TTGGGTCCCTNTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGNCGCTCATGANTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTC
+
+78B@+-CD@G5%4D'4:,3+FE.E*#<>90<DFC9/0/'G34&1@+&*"<9<.%+:H7A5'>G6.E1?1#1D##+=!9.5*+F:H?.5>,(:%9GHH8=@&3(HG,+B$*7.$%8@?G!/%-E
@r4798
CAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGANCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCC
+
)BGF5E)E('#(12B+F'@*4*DH40/!394>D<*"@D2=@)24A0(-/?!%?197:!#0/(=@>C4<"-(7#?)A4<&05E7>G--?>1C+:5'=)8$E-/$62!$;C>*G+8F(<$%B=-?)9!39E$($BH-;/2-#*$4(#."5347>C.:=B6:A4696
@r4799
CCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAANATCAGCCAGCAGCGCCGGGATTTGTGGAAGGC
+
,,H/1+.4$@A';,3+?473*8C7:0"HH;1(:8#:#DE+"A@9:B4E-.>7*@6C2:$705-"&79E70>C8'0B&6%%B4E@D&#*CG?E.H
@r4800
TCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGC
+
1E87:70A",CG89$*:310F=*EHF@4)A+B!EADCC&9'/@*
@r4801
ACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGAGAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAA
+
=.H7>%:+7:".?7(GG-9G#;G(>1(GH&:)%(A95-&36>754-%2A+5(C>3;G"3E=!-<)A8@2<$D5<&F45*#%?&A;.D%F)AD>0.H$=?9&3;:E-)>%BE;C&=G&(;9$BB6B>?6579%$$65')CFB!4B':GD?#1H.#716B?=F@@'@E/D8G0"&$>H:</;!!?847""1%4<5
@r4802
TNGCNTTACCTTCAACTTCAAGCCAGAATGCAGAAGCACTGGCTTTTTTGGTTGTGCTTNCCCATC
+
!#*&))&+*%*!+$'#&!&+)!+#+''"#'&(!(*&*((!)$+&&#''++++*&'+($%#$!!%($
@r4803
NCNGTGANNANGANGAGANCANGCCGGAGGGATTTGAATCCTCCGG
+
'%$$((&$!$"%&!""()!"+*&())$)*$""&'+*"'*!)$')!+
@r4804
TCTNTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGANCATCCCANTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGAT
+
687#0C=>690.4BH*68D%84D?B=96?)DD-F%-#H2?B"(F(H-1%)&%.B%)$"G>-"0<5<;)@?F6GA8573)B%0")A.6"E!E4=H*'1:C=%B539*
@r4805
AAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGNATCCAGTACGGCTGNACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGATCAATATTTTGTTTAAACGCCGTGGTCAGCGGCANCGCCATCGGGA
+
A4)6&2)B%)10;/%'-=4+"1#1$-*#&69"09%1A1"%6;B09F;:,5A':-07:<93>@2572><!B91AF38=5H)?#,2-G;"+2=G7B%/&"?*?)<271@7#.*0@$,C?A7,*$0*8:?"8!7&!FB,6G.+,@!4<4=!G1&F*'9B5'"!A7-@+97;*1+EH5;>*.==9;6B2<B39E;,
@r4806
ATCGCCCGGTACATGGCGAAGNCCTTCTGCGCCGANGCTGAAATCC
+
"1(&FEDA!D"H-$B/;(+D++14C@9GE*CB0@(H%-@91-AD7,
@r4807
AACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGNTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACC
+
=B.4.<8/!3B#6$8%G(3??9+1B'DE$2H+/3'D=,>"7160*(4FG4+;;6EH;"B.=-AF3A-3++)G+0!7*-7=&D<:C869F4-.72<@1/&(7'FH4&4>*>*F.FE.8*43(:9(34G=48C:C>HA?D4@H&;83A.C1
@r4808
TTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTG
+
(1:+$#+$)1D,$G69GG*A0562/..E0>%+62B?'=?5-6+09:>G33>0A>HE$@G2++9(7#9(25H7.ED10D*#E"<56447
@r4809
TATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTC
+
2.C>'G,D4%HB7):A92!D#,D?+7:GBH@)7>(DDG7H5$"?.3G*4BD1$*#&"C65,C8=;6&:3",8?:);*55B(?=%.&-C&-".0/)'3?(E=("<'"'$
@r4810
TGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAANCAGAACAACAAAGCTGCC
+
;-(;%D$BDB-#9E/-%,0?*:?!5<6/C!$$:"3@-;$4HE4FA-<*3+#A>C781D!B@70<G#1+,8G=G
@r4811
CGTAAAAAAAGCCNCANAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTT
+
&8H#880'.+#"/&A<*80/B31HH.)%!B;F#2GB%6:8:F998#7<"/B-=$>;11C)H#CB5(2
@r4812
TGAAAATCCCGATGGCGGTGCCGCTGACCACGGNGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTNTATCTCACCCGCGCCGAATACACGGGCGAAGAGCNGGACAGCG
+
:)EBEH.%H@;?/B9:<C&+<&9);E-;*;2A5#/@+<15C?721DF@$1D2"-%$.9'!1;H48'':@$.)=*=$8486HDF#<+8>!)@5)B%B9D43A:?%H%7+DFC3G$.82*GF984?:*E/@+E(@=11)<4/8+B@(FH5C$GB5@&=36H=#5=D:%H$6>"2)H+?6D>5<14CC"?>B":8D,!&GE0%!&+.7+DFC@7342C9#%")?-"@*8C5A2%(!9%D(/H")(=-H&(2+7*-B3=D&(&.$>;/4G>5!91!)",A4)0(/#.8<%97+%(#;
@r4813
CCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCANTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGC
+
=/.-?B8E?!G.?=%8!*G83!>-.)6(H@F=93B9+8G'>0%&61=)%.6@:9%A1-7<D+,.C8H=B"?F.2@A.=&A"#G,;)$C"("?4H?:G2$(8C.=D)<H3&B6:+1&@'F*(<1;'42A<A-H',2D%0,$.<!7E&&49B!1'H'DD$&A2F9+A(C2=/:?)#70+#-.BE&5*>;?)A/*+%8';:$597E-/.5,+"
@r4814
TCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAAT
+
=.*'246:G%$D2''="F09D59!$41%=>F5&2H4*$/(0E@>@H+:0?'0
@r4815
CCGGCATTTCGCGGGCGATATTTTCACAGCTATTNCAGGAGTTCAGCC
+
F@;#,D$''1'A$-:0"5/,E&$3):7=0$G:1?$4(H4D/!0@64/-
@r4816
TTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCAC
+
C.'1'F23%&83;2CF;206;28=67%65@%(1+<%?,"C:C!4.4AD/;<5<''4
@r4817
ACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCACGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTT
+
E#1201<E!FC37D2G))B(".%?*)E+C*('C3,;D$96C-E+DH11?(;<*8G@C-,F8?=C=468=$(,07@?),:-H,A1+1$314=0:@+!@<H7
@r4818
TAAGGNCAACTCATGCAATTATTGTGAGCAATACNCACGCGCTTCCAGCGGAGTATAAATGCCTANAGTAAT
+
"*%'#'%($#%'%&"+($(##)%&*$#!+*%(!&(+"(&*$'%($!(%!"("*!)%#&!+%+&##&$%'##"
@r4819
CTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTC
+
>C),D:2FD4.:$5=(F5/E-,'8&$?!,@8'E"4-!/(6C2217
@r4820
GCAATCNACTACTTAAGGTGATATATGGAAGAAGNATTTGAAGAATTCGAAGAGCATCCTCAGGGTGTGATGGAACAATACCAGGACTATC
+
E(F73=3"=D55A5=D-7#*59@!$%=#%&6(:"$88##&H,(F6AH>C$,%FD71"F>(+6#5?%B(;GD3<(B.0@@/9:3?3F=52D/
@r4821
AGTGATGCGAAAAAAACNGCGGCAGACGTTGAACAGTCGNTGANCCGACAGGCNCTGGCTGCACAGAAAGCG
+
'%&0:8.5.??1A)D%-'8#<7>=$:%"8DG@D5<C";8#F<-;5:="B@$HF*E>E(+*<&@B=9!<!/$)
@r4822
GTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTAT
+
,-!)!D2'!5$(;H1(-G1(4&8(!;@9'C$;3/&C#'4E@5A!!-<G&)BHB
@r4823
CAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGC
+
%&4:)"GFC)5G+H+13368(G@>;:E+-)8G(H*=,$C-E5!,))GA.9#:C=0CF!%@:'BD';22C0:,E&#C6+H!39/H!H>D-0@?=7"<B8"6G5H,8=F,A/F5@*9;:(7B/@#=**0/D<82"))69==-(!94.';)=#!%,2#(+B5.H9)EA'>9)0'#1%<
@r4824
AACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACT
+
%F=B+3+D#(6C75:%4:A@&+4*A+9HDA:H102&!3:#E6D,37$;7BA
@r4825
CAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCNGGTACTTTGCCAACTATCACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACNTGGCGAGTTTTGACGAGATCGTGCCGGAGTTCAT
+
:<(H$((;?@><F".F05/<HA"992,C+.4C6B#)95+E$:B,,%E4'!4A>2B4*9G==GG%%!76;9H5;F/.G<E1)$;EE"AH4!8';2<@5$?2:&90@:=AEE;9"=7%6%#)&$.*36#)D"=&-"<A,1G-05)*>3/99
@r4826
GCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAANTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGT
+
9+>)0E8;)?7F+7-%(D>(0!*F;6#*?#=H*-,5;C.D:@&@.#'/15G+8";F5B4B--6H*!?>4CC.HA*E!'25)=D-!/"@"D3?/E2::$86:4-G5B&=-H+&>>&F52G'BC?77!C82*6;'B#A801-D3&B%=&"<,'3D'08"4+HE3>A.%68G17!3)(.0*9>9<0""&(A18@)?F4&5285G+.
@r4827
NAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCC
+
$<4=B#4+DB!(*D0@G;1.H;/;/H'EBA<A+.83?:2$?.)"&D"=-/-H8G(;E
@r4828
AGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCGTCCCTCCGAACAGGACGN
+
5$@9!D,+7E1C+?-B7A0F.@2'9=:-'20@FAD%7;*>44@&)-9C=HB".4.=?'!#<$#@GB
@r4829
CCCGCGCANAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTNTGTTGATTGTCGCAGCCCGGATTCA
+
0-!6;2H!GH'.*AB&.E60.0(=?,+!*5?0-?"9-:76@->4:<.)=:/*&26F/$0?G'75&6$%&G%$;D->6C?DC("!=,B07H@>!B5D,6A;-:#981>0B79;("$<#@B-9;A
@r4830
ACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGC
+
9<#9D39B!!)H1=+;"C7+(5(,G>.%08&:H2,F++7<+G1*=@52999#=0?)6E$2F<#?:859+5;A12?8;H%01,C*B,F@6@!';
@r4831
CGTACCGGATGCACTGGCACTGNGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATAAAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACG
+
1(54,'+1;D3)3F$94%=6.,@7$6(9?>1))%/3%)F.7-9G*3-2'@2&@(A&7*0=1#>**A@7:"1?'>,-FBDB*'B1/?16>*)9)&E>'F"312'E/5",DC5'223$;G5%,!/D7A4*%+.3B=
@r4832
CCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCCATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAA
+
A@!2!(D(A/!D(32=30=5+78+H2D;AF.F7&9!$/9;1:1'+&H1EC3'%&;)8C?=0*2!/3=,?A%H9-8"*@80FB2G8/5;(?"7(B!.F</"C-?E%(--32=6-$"'D3$F4<=).:@!G<5,&<1A16A:,&D"6.05E8>EHE5%E9!0B*>C9260>
@r4833
ACCATAACCTCCATCGCTGGACTATCGAAGAGTGCAAGNCGATCAAGGCAGAATACCAACAGAAACTCAAAGACCTTCGAAATAGCAGA
+
1+A.+*>)>-;3?C-E.$D-$6#(&F86.50.H56E#F7,*&#9.=D;?5?2AGHF49,C?#(#GG?BH%0.D6?.153?1('$>2!:?
@r4834
TTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAAT
+
F'*%5"2FEFA<D<#:8,C+6"&/.@")1G-4,B:=+=%,G9B&G2
@r4835
GACGTCCTGCCACCGGAGAAACTAACGACATTTATGATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGNTCTAANAGCTNCGCAAATTC
+
*:9;#8$;H%1;"4#%7#181:<"1=F.D@DF?/)1@.G&0/+;)$G<,>G$'$6HHCC*8F+%@;<F,'G70A3C&"BF68@$@!6B!59;E("&5HA(E+G4?-D&G'C:4!#:3H%=("*5>>1:95=*3'E8-0#'(1&;5!!091!C&>
@r4836
GCGGCGTGTTTGTGCATCCATNTNGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACTCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCA
+
6E?D%7&E-9>B*A!.2.8BF056&:F!48/5FH?)%)(4/?B2=,;#5..'D#H%!$0'%"=@.1%8%A0E<()F1<A>$7&#>62$!=#D%B7'E'0?;9:'2*?E&,'4$39*7&&;HD*A4"@>*=@"(,?'%DEG!+7C,<;E&
@r4837
TGTCGCGGTGGTTACGTCCATCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCC
+
.2!+AA8AH@ED<GD?4":"/$>1F%(%0%+<2.,/8:B)6%@15D;?CF=9<)E61:
@r4838
NCAGAAGCGGCATCAGCAAAGNCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCT
+
#051?#1%'67-6#92<6(.F&">FA=52#.0>%%C.+%?9.$#;CBGA*$/+"()EC05-
@r4839
TNACNANTAACAGCCCATGACAGGCAGACGATGATGCCGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCGCATACATCAATCTGACCGTTCC
+
''((!&&$'(+&*#!#+%)(*&)!'*$!!))%&!'+"$$!((%*!"$&(!!$)#"*##(!%('%%#*)#*)*%"&"&*'%#%('"$*$#&%&!(!(
@r4840
TNANTCATAGAAATGGTGCTATTAAGCATATNTTTTACACGAATCAGATCCACGAAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATNTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTA
+
'"$#+(%*)*')#)*$($++("%*#((!&%+!$)!*%)(')*!#%$&%)*!&%#'(%&#$*+&+#$"%#'+*"*(*('%'!&#+#($"*$!$*)+)$#+%&+$+#&%))'*($*+'++&*!")*'$%"&+("#('!%$$$$"$(*$!#+$#"'+"#)$*&!&$%((#*)'%&#%$)+()+#&%!!)&)&+#'*&!&)')#$'*))#+!!'%%)$)*%&%&&+''**$*%()+#!&&'#$+"$'#
@r4841
GCGGCGATNTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGNTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCT
+
*(;1G+*D6G8*C<?$02:>=#:"17C6"4$(E2,B;4#6A#BB#@7E?GF?610B-/3/$$$-68#231,9:-C+$7B><.@=;-8
@r4842
CATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGC
+
G89B%DA811:$,")E3A#EG768>BD:+(GFA;F8FCDE75
@r4843
GAGGNNAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCANGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCT
+
!(!*''('+*(+"!(+%#$!*%''*$+$'$%($%+#''+#")'#+')'%+"$'&)%$#'"'+$$!$!&)%(%&)&"#*(&)&$)"%'!$%(%+##'#%'"#'$
@r4844
TGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATAATTACATATGGTTCGT
+
)2B5(.,5663,&AF>*!1=CB*.@1#%<83'H-<@CEDB4F;#5FH&3:;0?6',E@>"A-@C6
@r4845
NGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAA
+
".C!5H,1E7A8HCE25(8A0#H+B;?B<3-,(5GG/;)$670(?@C4D#E-(F##.56+HB.%.+(&"'>DH3!DB+G=/)3),%@*AE8B,%:#D$&#D?G,;H>4)->!B>3)(2#6,)H/1#3%<
@r4846
AACATCGCTGACTCTCCGGATTAACTGGCGGTGTCGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACC
+
.76E*@&$2;=*3(4/G9),G--E45A4>69@::<=%#B&+@/-$4>B/1*!97>E40/$8E'C?D<FD7<D$9/CF1583
@r4847
GACTTCTGCTTTTAAGCCCGGATAACTNGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAA
+
,,GB8$/+1>698$?+GB-0320+6,A=ACD:=H?)===(1)=;3#4-*4"37G&9&-6%C.!4/E)5B)73<;7!)'A9'4$.F9@<&E)8'AG&@=G#-3>F(!7&4;0G,38:>,@?E)7/>%**<&C82<23+F%=2"$?")+'0=860H,F(@
@r4848
ATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACNTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTG
+
38,B6$"6FA9$F1&%*G2@G>)(6.:+-':/3@)8?31@=F<693,%7$HFF!$4HE,16'01#7/=E3%4#G7'#EF+!/)%'BA)0%4;'B2)55E+&A+%&6*7EHA8(3AA3::!:&3!;,)0-'CHF*.+!"(2:AEC.3#52
@r4849
ANNACAAAGCAGCCGCGCTGGATGAACTGATAACGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGNTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAG
+
#!#.*(1(.AE$!B9%-34(@E:"(G"?+F1HC$.CC8@+"HH+0,DF/3+"4.,37-G3!;-%1?%:"9@:H+<'<-,@3->F5B?+E',95*B-;0&E+*+5,7('+C@8-,C;C(6#-?.6E4)/#5"66!;93E&1'EG)G&20EG;/&'7<@6'6E5/B7(06)'>7*5
@r4850
TTACTGTTCTNGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGNTGATATATTTTNGAGGTGATAAAATTAACTGCTTAACTGTCNATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTAT
+
13!/&,9H%7=*!48D1/:=#+=;#&A+4-1:&*:,FFB,;).517B9.!4<!0/F".+*C:2?%*?'7#$<F74$!H#G:2+0,$E@@:11A%EBBEFG@*=E!.+140:B5E-,/&@99G,>/);=.8->&.!6+52<%+>E2?H'!7-#=!B%+(*E8F!(?G>#EC+BA'!3,:&C9<!8F+3@0:9!G+3<+3C!8+%5A@!A7E0E,3)/+@9?1$@FAEF;.4EA/4D"7*<2').68&C)7C-;?-*#$0+/-E5A>7$.96$&*+03:D0AF9@<;?#FH94>958E#<>F4!H
@r4851
CTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAAGTCCACGTCTTATCCG
+
B#(@:99&&'B.EG,BC)24;+1=DE%G&:B5$#D,?+*3B5'>%;1%"=,F4:(<,C;4>(=&"E3#=-;+AG"32A)*$2>")HC-,432&4)"1@2-*GH=2!<&6*,F@6<,-;=2>7H5%,?B0F)!:E-C:'F$2&@!+?"EF-D++!F&0327"=
@r4852
TTAAGGTCGTACTGGTTGGCAACGCTCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCNTTAAATGCC
+
&+()&"*#!#("!&*+)$*(+*"!*")")%$"(+(*)("+&#+$%)*#"%#)&()&(#"+$*'*&"&!'!&+
@r4853
GGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCCGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATNGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTNTTTTCATGACTTCCNTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGCTCATCTTTATTTAACTC
+
1&.,=3"FH!8D-#G*H)5#;=>"?<?!H871<D!!)1/*#9,$+'DE(D)C9$>@+%D>$BB%C4>@$;GD%!)2/E591B2%0%838.7&>H+ED>!))?(9,5;)66GC!&B42!5.E0;-:.#1FFG)*"2*<;6<E&D5@=(@@A1827F?A":)=-84)(2/%!%-7A2@-5%G4,-@>&+&>F;&C)HA$)#'(2B6FG;?&%"+$::B%7*;4@+G')*8,-)H#@H6DB010##F6$E683?>."8&;@-0$$1D>!*.)/:(*;DH"+*C<-H+=$+H7(,8G4.D:<!C@*2HA'?:+9)FE:().E4%+9
@r4854
AAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGA
+
1,%%+A5@5H/5-5E;$@:&7H)C;$E:&E3->9"&2:$(%3*!(F73>F
@r4855
GAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTG
+
4$?;?25CG"0;;)B*4,#/&--7%!5<(F%>D1E@5?C<("+$>#81@A,92.0:*C32E"C/+%
@r4856
CGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACG
+
$-C0A6*>+.06:(0)=2!1GH,G010(G@82"(($C!H(DB)*;H4-+1.,2%!;8%6F$;B,6:C2A%B/1!?&0(@/+0A*&0-%"@#56;0/69*(8@=%$=!64<3,+"*1DG=.EF-:;'-!E,HE4(DF)3',
@r4857
CGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCG
+
H%:>?B&75>A0138/7*7F7<4,32G9E7&&>/<*,7E:D@%&'G4?B?G;&>9$.B=!81!;,'?1E5.@<;$-1E4-;#+H$505&:"*7:52A,.<#77:23.%!?=>)3"!4"
@r4858
GTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCC
+
/!4:@%@A)?$8C')88'94@&,/*;3<H?:6:'):/),DE:&B5'A&$433"=B<&=27%F2>(B)@;"
@r4859
CACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTNAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACA
+
C5<<9,AB+A$8$GC**>'B7180/<=99>=/2(.;%#89$F(G)D9+%9D1"HGBG82)'70F@G@41'G(.E;"D.H2B;.<94A<D.AE*D1H+-?H6,7D')H+-?.!@6%5?H(:*G0>+D9'0FA2'A&E'61<'@285B?C2$$63HH6(+221/F):D@B*0%06-%*5/!A6AF6D?,G
@r4860
GTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAANGAGGCGGGTATATTCCTGCAGTAGAAAAAAATA
+
,"0,30D*@2%?%'$=?H-1*(=6:'/:8@(+)B9"",7-,7H+6A.#8F.=/)-#0'CEED@6>3)297"2#@@>=52G)0,A-%%
@r4861
TACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTNGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGNCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAATTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGT
+
/(.D-GB4=,,0:,?2;9F4HE8&<+2'8'C5H7?B,E%;FD2A+2:GA7,1B>*D4FD!CF0.F&*+"=2!&C2=E8D2B&=E$A".A>@/>0$!-:@>GA(!*$HGEF@@=9B1!7H>*-E/7-0CC)):1<>1+!2CA-,62>51$&1,.0%3##2,4$4AD9-DH58:!4&('$!46?C>C'=E)3F)!H!5!0F"<2;2@*.+3))!C5!.*3C3F
@r4862
GTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGA
+
<#H/':#:CF'*/+A*FC$"44+0GAA3(D&8F.4>C6@/=%;=(#2!)1.>D<
@r4863
NACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAA
+
$3:!%;=0*C'F2.+24F@G/%7%<09*6+EG=E)D>=H2=H=7!%)7)2.@(GGD<-B(7FH*"&/3A5)96&>.A:=90)(-6(8A-9C8";;.GD0+"38,B"&G
@r4864
CAGNNAGCATGATACAATATGACAANAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGAN
+
"#!&)&%)+#%&)#+'''!&+"$$&""#"!''%+$!#"*)*#'+&!))"&$($"+'&")%(!&'%++!*(*"%$((#*!#'%%"")&&'+"*($%"#*)!+*!#"'+!)%
@r4865
ACTNNNCGGACACCGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGTCGGGTATCCAGCTTCTCCTNGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATNATATTCACCACNCCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGT
+
$((#!"%'$(#'%'$*))&+!'!""!&)&'+#)!&%"##+%#'!*#(&!+'&%*#'#$+!#("%+'&)!+*$(+'#+%#&&&!)%"#"+')"("*%%&*!&')+&&!##%&()"%+$("*%'+*"))($+%'%'#+$%!*$(''$(()")+)%!+&$))#+*++&(!$&####*&#%))&%*))!+'$)&'(&'"$+*&*#%%*)!$&'%%'&%)!)'!&+!*&"%"*$%$$!%+)('"!%*!(&+++!+)#&#!&##+"()"*("!&"()(")"'&*')'+'$$'"")#"**+$$"*#'"(&'&%+
@r4866
GATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTA
+
+$"$"&)(&#+*'#*#(*#**"(#*(++(*&+#+*'!'!'(()()#'(#')($*+##*+$
@r4867
ACCGATAGATAACATCGCATCATGCAGCCTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAANANTTCGCATGACTCAGAACAAGAGCCGGT
+
')'+""'&#"!!+"$$&(*#%+!!"%**$'+%!())!')$%#*+&+"*'&(!)*!+%&)&++")+*&(!!*"")%%%+"#)%""#+%(##!(''
@r4868
AGGCTTGTNTTTGTGTCCCGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGACCTTGGGTCCCTGNAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGG
+
0489*E;C&E)+BH>'1D$6%>,7'B=+)%(+A3/-:7,',!A=)=#DDCD4-DC'H"GD'A8/F:#B'3%9B>(D7)HH%D)/<5(%B0H4/.0":-)E!-0'7C#&E02?<$=5B5%52!B5'#2A18+#4!3?<?G#AG!9E%-?*)
@r4869
GACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATCACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATNGGTTCGCTTATCAAACGCTTCGCTNCTAA
+
?0#/H%E4986@7*G1-@4D#!%FF'9B**0*G%97B0*(&*1"=&7A9E8C*'9C-/*=(FD?.#%E38*&).=3-F@3/H"8H-.?79H)F7C>)&("0+@<)%6@.>3;39@B98EH:F5#9$B.(E7E:*3D.63F2A%-4(/7/,/:
@r4870
ANGTATTTCGGATAACAGAAAGGCCGGGAAATACCCAGNCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATA
+
!!#";;7F>BAG!9GDF@.>163(4H%D)!%E!)5*C@1'B:5E;&BC7!:F9!F#D='8%+!*;G/?+AA-#>=42%><BE?(5F-"FF4DH(D1>#"%:D>5A6=1=(+/2+&:*?FD"$%?=
@r4871
GCTGTCTTCTCAGTACCAAGCATTGCGATTTTGTTAAGCAACGCAGTCTCGATACGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTANGCTGTTGTTTTTTTGTTACTCGGGAAGG
+
6E35>(3A7H,$,1CD.=7B'(0+A7#A&>1<*EG*?)D*?;'B23F>9B;&.15=>DHF.8&?'1?'8?"&33B?-5)7H=/>2",,:@8!*/:(.DF095CB,6H;2<7-4-=2AA3A/4A><E,%1<.A(E-;E6#2;C))8@)97/0;,'4B;"-5!;;,*(1*='+>-#8,"43;":5,#6GE(96:BC#.8+'$/,:!;4-%;<4%>CF(D3;--1)*C!"&C###/=*'A/</:!?4
@r4872
AGTTCCCCCAGGCACTGCGGGCTTCCTGAACACTGAAGCGCGCTTTTGAAGGTAA
+
-6(=#,'82DA6C@,#:!<>G<-+H&E>.96<5FC5+@%/8)'=4-E8":?:.5=
@r4873
TGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGNCTACTTTAT
+
8?@*9'=?H,9C&C8118E3%1@7;$G/!.-.-)+,'38>'492!C:8A>4+A(+H?1;..*9
@r4874
TTCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGT
+
!3>.H):0)=,'"%&</:9!&;-?26("1G0/<=%?76H%925;;BB?'<%*7GD32;.!'&4<4:%8;8"$(F.>)2*+H
@r4875
GATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGATTTGTTTTATNGAGATGATAAATGCACTTCCG
+
<$84@:>4C$89956CH5/($:.27,H!,C,@*A6?E3.)(#4F83CC"D@!(CF.=:0<F1/@2GH*(6>+'+H,=67=G)E!B+H)@#4F*<46,7D&27EF20E/
@r4876
CGTTGCCCGATAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCANGTATTCGTCACCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACANGGTTTGTTGTTAT
+
#+)#&*!*&"#*"$*"!$)*#!#'****%#+#*%(()&!#%**)+&*+((!'*('!*&'!&$'$&($$%'*&)**$&"&'("((*'!!#!)%*+(&!%&&$(*$#&''++'*))#$("!%#+)*$*'+'!")&"'*!%)()&&&("*%""($#*&!#)
@r4877
CTGAGCGGTTCAACAGGGNCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTATGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTNATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTAT
+
3.(F5&DB#),E2:.9/G@37/,68<0G1A-!=$*)<%25=FDGE*"0&;);>@"=#+7C<-FE8.DA%2.DH&-*,.7*C%#$3DC!(&F<(6;F>3!F<%$.<9D-D<(7A>92=(?FG;9&B2$848#'B%@:5,&)=2<F-.2&*!>8!$E*-!"DD;6:??1)31&<=3>0"-%2?>(?D4=?%'&6@'0*H?C(F/&B"?9.8+%DCF2G>D:#@<5":0&/#E>:0&(0B(&H&=?9B0(H%HA!EG8/.$/G8*F
@r4878
CATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGNAATTCCATTNTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGG
+
8:#A?";2(HC</5:6.@G"0,(-$2"2-/"5FF,?C94/11<%BA?40$B55$"(:,E>*+GD,29,H><-EC!E%>*.<)'(6<E21*0%BDA,5>E6"/%B&?89=$)%7%!
@r4879
AGAAACCTCGTTGCTGCAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCA
+
@:8*,576E;3<:D.,7@4,A'EH15E<;56:3)A22#@>;.HB<H%<:(H;.E@4"C1DH(4&8"?D>*@1F,@.+-=#8)(>(7+H+>$,@<66E68(2CBE@/BD>(!<"F@381GBA."!*1>9G
@r4880
GTATGGTCACCGGGATGGNGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGG
+
(58-0A*5;:4D:/.AC)9'2#20:2A'00D!=E8?=F#'5'0C"DG$(E%"CG4#/@9,6"GCB;F>%>8F30"B3#&#,8C9?="38*"89'#0A:%H$?3:/HF9?";=%$CD0"CB2#E--6-38-1?21"
@r4881
CTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAA
+
7--F(5H)2H*?!8DC'H>=)792&1".,+8G%7E8H):!22"C//8D2!=@%.57'&@EA@16;,7&8BH5G?%?.1*
@r4882
TCATTNCTTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCANATCAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCCGNCGCAACAT
+
=3<'?8;>F!EA4C(,7,/-10<6)%H,D)3A%7<":8H0.-710+*865,%)'.#=.<$9DC29:4,2$!,(6*4.'$>&:/>F+>%,D'>E!5!<3D//8"FB!6F-.054)-$'?F&/9:.4:(2/C@>@/(7(>">'C2%8?;8/2=54B30H3+"H,::
@r4883
GGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCNTGAGAGAATTTGTACCACCTCCCACCGACCATNCATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTAC
+
E73B=*A4CB,<H6F!7.F9$1&'-*),&6%E=?BH3C-"#=4%C,BH??+%$"A-F'"7,%&B"#"2;@5'(F!#,&F<.,:;$E#;*(B$:)>B&)#<($)9=FD<B6#75"=AA>)F8<GG54A#(A&"=3FH5*52*6)'0C('E5%/@
@r4884
CTCATCTACTGCGAAAACTTGTCCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATNAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCANAAAATGGACATTTNTCACCTGATGAAACAAGCATGTCATCGTAATATGT
+
5?!(?8E+6F#)$+B40+<&E9+,0-GG5<H0F*$>EG-'2=H/*>?=.'.?20"'33>A,2$='#78>&4<6:!)000+$?4277$.24,B$24C=01)<GD2=8+551@)!,*GG:*(%D=%DED*7-$/5#5"HE95/./.9!"!E>*B0DF(D-B<;A.+(!>@&.-<>H*:)7?895%,$7H(./!1;#B
@r4885
TCGNGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGNCGTGGNTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTA
+
#$#)$+*($#+)%%$#+'$+($*%&)&&(*!&!+)#!!$&)$%"&#'(+%#$''#'+#$(+!)+('%+#&('%&$%("*%""("&"&!$!#!!!+)&&)'#%&)#*)('')(')*)"%"'&"$"#)$'$#"&+"#&&))(%'+*)%#$*!+%(%'"")(%""+#(#"(("%**++!&(%"&"'$*(*)((%%%')*#("!%'&(%#**$'(+(%'"!$(!'
@r4886
GCTCGCTGACGTTTCGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGTTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGT
+
*H6C1/C9;:13@%'*2;+A-'%/2B98!;3,D#,D6G..#6BG//2!E=,##-G%HA"0EFC5,**,?/F<'6+@62!@/E#4=8-EE/!<-46"C#E5*.)),!9H1.H1D,&/6;75;(0:3;F/HA"&A+9$1;.H4+("?7(AC"@;!@E9@)%=AC!8!6,D#D;GE-9)"654<!>#%1
@r4887
TTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTNAGATC
+
G5#334A!?61F3-&%A3AG9*,#E=8E;*;/<E$4?DH"%&'0)=A(#C8/%BAH0H*BGD5,4G=9&E!)
@r4888
GCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAG
+
*3?#:0/:H4D>#609;)"*F),G""'GC8.9:>(&!-=/5=&
@r4889
GGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCC
+
%-F;1.0/=>1<<E0<@%68/5A+(7D?)#A"+/-=:'>F=A?1+:B5(AC+%@9C(3)
@r4890
CAATTGATTTNATCAATACAACATTTGAAGATCAAGCAGATA
+
E%4()<$/5-G?$810D074/&<(2B0/B0.*0H2/B%=(-6
@r4891
TTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAA
+
C.9:&/";G#F54F2*&AF0;3"D1:D)D6;'.D/50*;3!H28B(
@r4892
CGCCATTGGCGGGGCNGTNGGTGGCGGCGCATCCGCGTCAGGCGGTAC
+
DE.+:(:!G'5;HG'87B!'9)%.9A0=F4,+):;9DA#)3<::9=.>
@r4893
TCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGNTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGA
+
G0/-08-+&-;-C18#8!1-8)$3<)21>++52E9.!8;%(F8;(@(12!*<(90587.F57!/<5-#1/$+?'+9,,2BH5B)D",@&EC'8>*>D)1#8F(==!)-=H4;9<03%0/0<&G0,19)%8D.09E3)19!(7=##5>CD8C-H''<(8,"8"9F);9)#$2H2*(!%/9H;)DC;:C(GD::4
@r4894
GAGAAATCGGATAAACTATTACAACCCCNACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTAT
+
08=*>03168!3;0+8?%@"#1,(288,3-;77A),>&G@E21E>/FB;$?C,)C*1:E#?%@2HEED%&H!G):6B6&FA96)!$B9F-$4H/D)FH@1'5954D*'"D25-1,**&+92174D+)HC'-<8:%%,C'*,B*=+&,4*-2&98(5257@+:8>2/05$+&<E*2D6@#12?5A;0*!+
@r4895
TCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTG
+
>5E473.:89B0B)8B'17+=C,FF.GFGG/0F7DG;EE70)=9&F'$)%#D'CH.H?$B(?#*7%<72:!@>#*=%?"%"8/("D?F1GG!24-BC.;D-4<9C3E5.":E!()*9<03.!/B4'8F5.E.+"0#/#H.=B+0&@G92!$<=F).=2A":;$H;@24&%
@r4896
TGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGTCGCCGGGCGTTTNTTATTGNTGAGAATCGCAGCAACTTG
+
9$@C"!7+&1!)BEB*A2-G5</64)91E;9,D:)0/5AB,(A>9%AD3$D476&D!%!"7*H*<>(4(8E:%#7!E>!$;*)
@r4897
GNNNTGAATCAACGGACTGCGATAATAAGTGGTGGTATCNAGAATTTGTCACTTCAAGTAAAAACACCT
+
'"$#+&*$(!&%")#!"%'!"!+'+(&*)%%#)()""%(#!)!")'$*'%+#*$+*%&#+*"#"%'!*%
@r4898
NCTCNTANANNNANANANTGNCCNTNNGCGGAGNCTNCCANTCGGGGGGAGGCTGCATTATCCA
+
"&('!%)!#!!#(%*!($##$""!)"'*&&%$*#&(!&)+!"%#'+"*'!(**)#*&&)!$&$)
@r4899
GCCACTGAAGCTGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGC
+
,*$=,'#+*!,(:$'F'72*:*'%'-2.>54D36*@'A7G(476G7E02$5E9G659B7CD*,)2"3&E'.&>H;B8!,<81@B&!#H/"75$1=%>?:H>6/>/6H-((++?.*2'&DD-=A>7:#A8#B*AB,1):3$B*FG)!(>9
@r4900
AAANACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCNGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCCC
+
D>(922()D):!!2:4/3)G9<.(<,.B:(>1*D;<--.=6+%*HC@=2#)/@G1B>9*;C7:EF+GE9,E9D8>D4*9HC0'9:;$!-CC-(1C<
@r4901
TCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGA
+
6*D5DG528,!E'272"!1G-+#%(H7<$?8</?1#2.69!<DF2$$>#G;>27A,=:2'%"?!5&."2F-H.9)#;%
@r4902
ACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCNAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCT
+
BF<+/!=H74=9764?@)1=8/&A81%01,F&:G:3)A*&0)F:!)796>F76(A$?'#9#'H&H@A*A%D,C,7H+E@AE:2'B*5(6-/6H.28'!!C:F/597C9#%:3=*D649.>2>)F#$
@r4903
TGAAACCACCTCAAANGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAAAACCAGGAATGTAGTGGCGGNAAAGGAGAT
+
,/C,?A/>#1.':);?,"!H,><E)4F++%9:@3E/H&.!2?C?6$21H*2*?*=@8'+264B+1/,E97?&$9C7F=;4!,**"!-BG>>$<E6/'%(F1::</85>D6)."7E/>"FB)//%80#)/;H,%850*<C*H&=A&-#
@r4904
CCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTT
+
C'1:>"'E.#=E=5#(%83:%-GD?"C!5*%>*A-HDC.+>B*9&564;(FE%>8B<0GD0$;64?'+!(39$H9!"E7+D2=1)5:&>@,1.**?)8-%4226#B#):+/9A//41>925AG+82.
@r4905
GCGTNAATGTTACTGAATCCCCGATCATCTATNGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAA
+
)*)(%+'+")#&')#"'!('%)'*$+%'%(!"$$$+*#%+"'(!*%%'+###('*&%!'*+$("%#$+(*)("#**#+(&*&&''$$%+"+&!%*%"&!&%!&
@r4906
NTGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAGAGGAACAAGGCAT
+
#?$6*>H*+C&%BHE&83F-?,>=.6;/3*+"($/DA51!E@$*,A?"0=,;>4+'
@r4907
NCNCNNNANNNCACNNANNGNCNNACNNGCNCNGNCGGTAACTNNAANTNNTNNGGNGCNNGNNGNCCNNNNNNCNATNNNGCCGNNTCNGNANNNNNCNACNNNANNNNNTCNNGANNCNNNTNNNNCNTNNNAGCNTANACCGNNNNATNNNTCNGGGGNCTNNGNTNCNNNNCNATNTNCGNNNANNGGNANGTNCNNNTNACCGNCCNGGACNNNANGNCNCTCCNGNCAAGGCNNCN
+
#$#$!$!"#!!#"!"$###"""$"$$"""#$#"#"##"$$#!#"$#$$##"!!!$$$$!!"$!!""!#"#""#"$#!"!!!$####!$"#"!#"""!$"!"#"#!"$!"!"$#""#$$!!$!"#"!""#$##!"!$$"#!##""$"#"#$"$#!##""""!"!#!!"$#$""#!!###!!"#"!""$#""$"#$"$!!"!"#"$!$$"!##$"!$##""$#$!!"!!#$#!"""$!$#!!!$
@r4908
TNNCNGTAGACGGNTGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAAT
+
(#$)"++#*&*)&#$%)$#(&()+%'&+#"##$'!'&+!"'("($*&'"&!)#%###'"!#"!$+&$$$&$"("
@r4909
CGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGAC
+
D>&GCB?/(/F?(-6:.3G%C<F6F.H!<G">:>70-."43/0@?>
@r4910
NTGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGG
+
!B<.41D#'-'.&B5C.>58?,6A?>'(1!09E*2:;00?,
@r4911
GCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTG
+
A80FB6,B61G0C%58>,/:E'D8$<>6E05$3!;)<"*<83%F-9)2B)4<#;60$FEC*"9*(=G.3"B7&F#=D*@8DBA83!+AG;B&HC($;H,77@G$6;)A#<>B<+"F27=7'#=;&B88D.62D(?;->1C%28D$7(B,=+*<BDF!
@r4912
ATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATG
+
AH2(04-#$D."'DC3)&0E!GA@7C9&58,C/E":<FC+C-HA+<(GBC5D#117G)9C#B7F$=$=#6C,0A$4>!D77<=%F1F>GF*#8H53.@4*+%0;/83;7A9<>HCB-D"D/&**G-7"G5*,,(F'%G91"(H!&$GE*BG8(+:2C>!&=4E>.E+<,0:9F.!AA.)72
@r4913
GTGTTCTGCCATGCGCTCCTGAAACTCAACAACGTCATCAAACGCACGGGTAATGGAT
+
8B<,G0%G39$3B1>;#,,66+:H5,7@&H51A7/%3A#C0E6+92@F!!/643)/)=
@r4914
GNGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGGTCTCCGCCTACAATGACGTCATAACCATGATTTCTNGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGATGAANGCCTTACGTAGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAG
+
#%%#'+"!$&*$('+(*!$!&$")*%#"%!)*&""((&#!+*&"!+*%$+)%%+#&++#'%%+!%#'$$*"###(!*%+$'#)"%(*(&$#&*&*'&*&!&'**$$((("!#)$$+&+*(&$'&(%(&'&%"*$"'#'!+!#*)++*"&+#"*#*+"!&+"'$#(+'##&(*+#+%$*(+%!(+'(#(%*++"$"!
@r4915
CCGGGGACGCTGAATGATTTTCTCTGTGCCANGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGNTGGCGCGTAACGCGTCCGTGGTGGCGCAGA
+
<7G>"1/BBB&)C'*:2$<DC9@%*"-?@'6+:$3<=,C28;*%=H@A?;*"*!E(F'#:=%E*E9H(G$@+.,$"78&;,$E#"HG!&:H'4/$"<66C$*0.75B0):*4F)F,/8'#?
@r4916
NCCNANGTGNNCGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTT
+
#)*(%("%&$#+)#$#!'*+!&%))%(*&!*$!))%+$!*%#*!'+!"()!%&)'#'!%'$+()"&!##&$"+))#&#''(("'!+!'"$#()%)(#
@r4917
GTCCCATGTCGGNAAGCATAAGCACACATAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGTGATGCGGCTAACGTATGAAATTCTT
+
3--)-$%9A-)=7&@G>.6:'2;%;HC30%GB%"@!++G7-"*G=#+%+%4%2F!G**87EDBDF"?AHC'A!H17#5>B=>-&-C62>*?A:(:)G"1(BG:4"ABC-2!=%=G%6!9+;>$4@D46='#B-00G*22'*D9,53A*?2=>F8-3*,
@r4918
GGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAANAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGNTGATATTGAACAG
+
89#'8&0/:1H:!A>0",/0/=3;EE>>++&7%F/%03"14/>(.6<2%9742-5?=68<9/:#+:!?GA>4@:;(8!#'(<&+%B-+&<+F$C!99>5,.6,D(3">0B=0D>5@G.5"?#(4*AABGCC'%<=!'8*!4($$0
@r4919
GTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTC
+
+$E3H9AD@<@5:+;(-D72.4"C=9HD-2&-5:3;136*;5E292703&?#B3,$-G$G;#46C,,
@r4920
AAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTCTAACCGACCCCAACGATGAATCCGTCAGTACGCCAGNCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGA
+
D("2+@+A0#'!7C?*%?#!ED)4C.A235*/;@6D19H/D@7@#27"?,?C=/6!>#+F"2<"(GH)&=:;-8=+!"E+>45G').364$$!&AEA0!!'!FA9<<*!-G-7;75;(-2ABB77;9-D)8!228@,(
@r4921
NGCGTGACGGACATCGGGAAACGCCAAAGNAGATTATGTACCGAGGAAGAATG
+
#9%;1,%23.'9;'/H,?>"C7+0<%E4!("$G,B*268D)%7+)15DD++4F
@r4922
NGNTNNTNNNGACTGTTCGNGCNCANNATNATNNGCNTNGCTNCNAGCCTCACNTNCNANGNC
+
"#"$#!!#$!$"!""$$$"#"$$#"#"$$"#""!!"!"$!#$"!####"$#"##""$$"$!!#
@r4923
AACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCC
+
E:EH0B0,111.AE?#DA58#:-?6)0G=./E$B:8+C1("<(B38D-H3D%@;8':+%B3:*>9B=/1!B/"D:H',1H/3A'*G0(8@-162A5#$*83
@r4924
CGACGATGGCTACATCGCCATACATCCCCTTATAGGACACCG
+
F9/&?D2$&.DA?1>B0%*B&21+$FG#'521:/#@#;5$9@
@r4925
ATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCC
+
1+5-G,;B./'#+7CGH5;2,-4?!+1$-6?$?:.'#613=D)A4DF?G>%
@r4926
ATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACANTTCTGGCTGGAGTCNGTATGGAACAGCAAC
+
B?*"E37GGF8H,7-:F/=/#59<.E6>8..,2)6;9:*:A4D/1-BC4<G-/&)@+*6:0'))GD-@A.!$=D46:B2-/1'2$)=)/+H,CH)1C(AH;$7=?-2+@%D,GE*4*BC4(D2(/,.4';+%*"!<*D#4)->/@""#6ADEB+"E(>9E&@8&4G.@4F00$AECB75,263;>7%-!/?6H5<9F))C->3$<3$.C;='E!+@$F%!@G9#26;''&)9%70@178(&,G2
@r4927
TGCTTACGATAACGTAAGGAATTATTACTATGTAAACACC
+
G;D!;5DC"CEB"=#?%E23.+?136?:,,52<HE26D5<
@r4928
TTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCTATTATCTCCGCTCTGGTTATCTGC
+
?+787+>88GG##E!H6G/=A1*$AD=(%4D=.)&:B7*"%/"7*0;94H$B+9.D'@15C0"9%@A3955'&,7!<?86E3$><))>7*E'6HD&4G8'65,F@81F%?#D:.28H./$/93++'C?#E9$*!E9*?,3!7=8'%6B<E<$08B4%.H,*-+66A$@%+:8$>7EE)12-5(:3=,4":C%AG*7<,E<36
@r4929
NCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTAT
+
"+$*''&+**%""$$+"&%%&)"*+)!)'$(&)"("'+&("*!&'%)!#%()
@r4930
GNTTTTCGTTCAGGACTACAACTGCCACACACNACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAA
+
()=+)3!0;F!9&;B:D7#%&1!6+1+%>H"0.5755$126G>/+H!E*C*$@@:;F3G',%@<&37>>H8$DCG?."?&'$:H96F>7/9*GA%!D,9A+H5".35C<D"5?<40D
@r4931
GAAACGCGCCGGTTCTGATGGCGTCTTCNACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTG
+
0E?(5=<5=4?D0F4G8C82<6H1#>/+#$)&&.$+&<!!,,'2;BC31A"2%)F>#>>-+E,4/0%(C
@r4932
AANGGGATGCGGNTAACGTATGAAATTCTTCGTCTGTCTCNACTGGTATTGGCACAAANCTGATTCCAATNTGAGCAAGGCTATGTGCCATCTCGAT
+
(!"'%++'$"*"$"#*(%)$"#'&!'&')+%"('!$+%$)+&$(")%%$)#+$&"!+(("!&'$*#'+!+)*)*)*%%)&*!(('*'(&!$*#!*)(
@r4933
GAAACAGNAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGG
+
+>):"G$H%5D8F,)#0#"G.*5*E#-!B.@>!;9*1=";-0E>8G)#H8"2<,E
@r4934
CCGATAAACACGCTNGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGANTACTGTTTTTGTAAACGCNC
+
*5ED&21H):'E$="(@''.;G2+(D:@)D'65:='/=H+H7-2=.B$+(-/$%@,7H257)H1/$H):2$+D<>@*.$<!9(C%9C4/9=-3$2?1G61"F9$<?>B)(60CD=>>.F#0B>D
@r4935
TGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCNCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCC
+
9@3-.7,F+76+?A$4B20@#D+"8!',6(CA?)=HG/D2;)%E)1B;H,B>%5D+5%':5>5!3.?)A;%D@#&./9G:3B,/*'>?4H9G&0*(/<&.@=#@(>*D=:>20#%E'.&!+%"/>%1A!92$()(4!1;!C,BD<@D0E'GE00>.CG%D3!-'6@HHBC>0(1.H%E?3&4D=.?A=1?#!#/,C17F.E$=2&&=+7GG3;73,DA<8?
@r4936
TGCGCANGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTNGAAACCGCATTCTGTACTTTCGTG
+
;.HGF7'$2-,14F7?A/-*#8!1#/)D&-6#:H<%%9D$C:;4*?@'27;<@,5==?-@23?B;=>=!=7CG0A?;H+
@r4937
GCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCAC
+
H"9D5G7>5'63EB2D!7+8E8:--;=3:=4A%>*:*487>:-<'D+'H1D<<&4?E0+)0$>@"(4>(CC:2A2"<1%!F:?6F
@r4938
CGCCTGAGTGCGGTTTNACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATNTGCCATTGCAGGGTGGCCTG
+
&?&<45*<6":H/CD@A08$4'%>&+?A3GH:,<$'=4+;!F7C-<8C?C8%C>+F0=.8)0HFA"9@2)&%<5#E)C@-B<.5$B*;E/9E6H"1=9=7&3+A22(
@r4939
GCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCC
+
>8".?FC!?79)4*((6>@HA'%BG:>7"4:+282A/&D'50.2"*@,E-EB*661-(*B93+!4<$+7)A71914#;;ADF%.$6)CE%)477)?H.$:55+8HA/6>*3A>2)2'>6;")58-F3&(=
@r4940
GGTGATTTATGCGNAATGAAATGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCANAGCAAAACAGGCGTAAAGATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCACCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCAC
+
.A8..2$B#0%"C"6<75?1).>'!>H/(0#D+4A9B:+2705->*6:#A!H(C<B2)16$7H2D;)&,C3E7"2++6,5'+<4G#%F2$F-%)::;+5(./2%(%'993G.(A.<(F=E-<=?-B%=08826.+E-&#?,E<'GH4*/7>$8%HCH>G.'87#<0=G7102"E6><"34&C"/4%7$*-G:!E"'0BB2B;$6-/3A<F3=!F>6F?'B19?<8!4%C%'"1#0&D=
@r4941
AGGTCATCACGGGATCCCATGNGCGTGACNGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCNAAA
+
@!@/7:<%?B/=82,=>.074A%7*4:"?>)44"E59?B6+#.<.,=/GFC@9F@/2#;@E5"AGCG@0A;G.*3@++-'A<2'5<740$)%+G<
@r4942
GAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCNCCGCGGCCA
+
H5554%!40*7#>37%;8$/'<@B.9DFH7;/"A:.6BC':G8GEF$D';*C=-'/8#
@r4943
NGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCTTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAA
+
%21'A)D1?606FEH7G30H$:0)@=-C;,"@@4C;875A'F>64>%:@7@*1(798;(5>#BFEB,*CG6$"@,>01;A)8F6H>@9:5E,>,!*#7:7F3<E*=':(!&!%:A#B&?41%'(CE,(2-8100/$*4&4/F(
@r4944
ATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTC
+
224F-BG=?06;(2%H@2$;';,8#5BF=:%F1@03AB"%++-::C(&.H.B!&B:63H@=C6%'D=$5<3"*D*=5?>;>@(..;(=B3@0.&F:!A:',&B.!&5B46::!70/@5.1-
@r4945
ACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTT
+
F08=E%&A-'=BB)=4)C2!8*>4;6>@#>7'#G0+F3-)1F*;DH$E2C<7(->,.D!&G*0#0$)-:'"&/)=%7!
@r4946
GGACCGCGTTTGCCGGAACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTT
+
#DA$&-=,5-B7%:77:+?H$@#G,:0C!C50&);19GFC-1>7:);@1,4$*?#&<53-F1;83>+!.5:F3";;(A23.%2="*.93!;
@r4947
TTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTT
+
F,B';1;1"3.5,5%4;>A*<0@+?6:=;:@HC!55!G<@>2."568337#0!6E>6054A7$='&(=%F'3@BCA
@r4948
NGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTA
+
)$*+%(%$**%++#!)%"&'%#'##"*)"%!!'(*!#%'&%!"+
@r4949
ATCCGTATGACTACGACTATCGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAANCGGAANGCATGGTTAAGCCTGAAGAAATGNTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATNACAGAATAAACACTACACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCCGATTATTGGAAATCTTGTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGNGAGGNTATGANCAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATGGACCATGNCGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCNAGCGACT
+
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
@r4950
TNNATATACCAGGCATGATTCTGTTCCGCAAAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATA
+
('")#)'%++!$!!#*()&'##%"$%*)#")&+&(+(***+"#')$(*$%"*""$"%""++#)'#("')##'(!##("%)'$(&%'$(")((
@r4951
TTACTGCTACAGGGACCCAAGGACNGGTAAAGAGTTTGGATTAGGCAGA
+
:8)%72C&=)'%-E,'(4/@"B*:#C=-+2'2?)@)-@#,H;.?53>?4
@r4952
CCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGG
+
296A?G(419GH/-+?"A)FG5E2)9-'36-1%!!7$AB%0-7)-E8D3.>?/)"D9F3</2.7<H8(?G('$>7?/!$!4*@00G!1&!9C#8!E%@F#:0?HE/B(
@r4953
GCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTGCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTNCGTCGGTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCG
+
..@0'5*0-&1,93B$FE5A+92&D?.>&=?-A8&4HE,6F4.*=*EH<2.F1%&H73@C78>7;F(,0&<>DA'119H1E!$23?GH0H@180--F!.6!A(.C!E0F<+@$6*@A67-EA,>(H!"+1D>-3$&D&B(!6G"(,E8945@8)D,()C<H+<+B3;*/3.7,:E(A%C*0%.3)#%<C1*#)5-0020)%?9&&@6?18?%G7"";6'5<$C(-8?G<G2%
@r4954
AACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGC
+
;*21H,*-;-?#:!1>;8-7'<#;#:"6139H+(?5>;<F#<>=">-4DD!3HE8B>9
@r4955
TGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATA
+
A*;+<G=-%#"#+EH%9%$F%%9<3G*>73?,F72'./3/5(87(9?1E=D-03%84@:#/"+%7)?HB/A,&B'4G-2D,-5=B+92.$&:5;=9!DBH*=90(C0-57%++>5++F'(*E908#:(G=E#+,3&28C;/0,1
@r4956
ATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAACTAAACCCAAGCCAATCCCAAAAGAATCTGACGTATAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGCTGCACGAGGAAGAAGATGATGGCT
+
=A25*?,%=2-(10);G>-:B'A"3G1@%/"+HE8$):8A)9E99G@5/.'58154%$C6/A&(B%1A@1-2#=8B240=HG!5D6"E10&-0,41<17&:>A<(9&,-'>><("+D'H($'?4F?!"?/-E4:#);)"77G5FCF*G*"8(<8G/2($C10,5EC<5/>@+E5@?7*6!=(/:"&"61)/)$2,&%B<93G+G&*0?.+'?1'H2A%=6<%A9,/!A24-3"6)'<@=982&0@'<8.8%'2<5?+'==%7'%3/E(3E5?9>'"#%=082#2>275A")D:H)6ED#1.:%)'%=!:?,.9F?9.5
@r4957
CTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGNT
+
2,".)G=D/E&:E".#"0@*>"5")"F2'A7/',E.0(5!0)
@r4958
TTGGCATTATAAAAAAGCATTGCTTATCANTTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATAC
+
D8@!95".@=;3&C238&!*+()'/;6A7,58&<25B?:&,;=94:8@$E,D',G==0,0E7E0*B/748B<B$+<8-E$3#5C:.(3@,9&,H-#H;+A?-6C)4.+1*%H3#2<*2#89
@r4959
ATCGTAATATGTTCNAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCANAAAGCTTTTCTAATTTAACCTTTGTCAGGTGACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCNGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATT
+
1C')4+G<E0D'!,!7)DH7;D/*282?AF-(6$'6"@6FEH;>0@HF/"HB%43D<8H?3@!>"31&#$H0#B$@2"7CA).D5*59.9)4"C-16,#?(6#;B%A37@3(=+)$7HE'ED3B=38$H6-H:)H$;@@.(HF/!&*+82:9G-8B:2/GH$55-:1&9)+A3)7:5:45@8)<F<8*'<?&9C*-;H54'@''$13,=#$+G6#*7'!8/>7920)'+6B3@>37>1+%H<1G&
@r4960
CGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCT
+
779/:0",::,?H4E>-5'B,>(C7HC0!6&?1<BH6%C>CC/3?,G7G
@r4961
ANAATCAAAAATNTATNTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGNCTCAAAACATGACGAAAAACCATATTTCATGCGT
+
$#E/'A>:%0B2*8-0:F$85$D"&3H@#D+H0.'4=.-B6C($@&<*>##7>*%C/$)6D/(("D1+B4A*.#F(,D#73.H-:/8",B'CC@<@0;>#C::&H<"))C?F=
@r4962
TCGCGGCAGATATAATGGCGGTGCGTTTACAAAAGCAGTAATCGACGCAACGATGTGCGCCATTATCGNCTGGTTCATTCGTGACCTTCTCGACTTCG
+
E&0==<=4$"0@)+D-57H)>+;&&);AC!H5<978,F'%4190."D9.D).?E&$818%@C3-';)!6F;$!159D0+"1!)A0%.B4EC%*0H0DG
@r4963
AGTTNNANNNCCNANNGCNCTTCNNNNGGNNNANNAGGNCNTNATCNGGACAACATNNTNGNNTANATNAGNGAAGNATNNGGNTCGGTCGTNTNNN
+
###"!!$!$"$$!"$!"!#!$!#"!#!"#"#"#"$!"#$$!#"""!$$$#$$$$!""##!$#!###!#!$!!#""$#!$!#"!!""$#$#"!!#$!"
@r4964
AACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATNTTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCA
+
.9?;'*C?#5/B#?4#8/*9F#G.F(H!B7"D%26F?DD&1A1GD,6;7&(29#,2G:?28HA&%"8&2;F</;75$@/*.H4?6G(&51HH3#2/9D3,D5/:8,!7$F.5&@C$F0F?@=C(D"$>@/8=.,!(#'3*$!').+H59'6440<F:69$H+
@r4965
CACCGTATTGCAGGTTGATATCAACCCGGAGCTTGNACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACAGACAGGTTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGANCTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGTAAGCAACAACCATTAGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGANTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACNTCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGC
+
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
@r4966
NCAGAGACAGGCGAATCGCAATCACTGANGCTATACAGGCCAACATTGAGTTAT
+
#(DG7=4B0-3@%2HB97("?8%(7&1F,='19>$H0&$=+E;C<*C'(!>>%&
@r4967
TCNAACCTANNGNNTGNCTGTGATAACCGTCCTTTAAAAAAGTCNTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTG
+
$)"&#"!%(%"&!!##!(&'#+!&(!*$!%!$!)%!&'!!#!+')#')&)!!)*#'#*%!#$)*)#(&'$"*!(#&(%('*#!$+*!&(+&#
@r4968
CGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGNACATGAGAAAAAACAGGGTAC
+
"+#%!*%($''")#(%+"($$($*'%$)""!*"$)#+('+'((#'%!*$+(!'&'$
@r4969
CGGCCCGTGCGGAAGNTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGG
+
+4BB!+.D'$5*$2@"*=0+A+9C#!'*.;7-?;"%3B;,3?AE?4E2)"0.E)20&*@HC.BF'+B'78G.FH0&$)<20%H0@2
@r4970
NGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTT
+
=%+.3+03C)+$@901;G":C(CG7)6BF=E*5++/@E&6/*F=#!E$4>G&;DB#(@-C-H*3!/56E@51?,-<F.#>/;%1;
@r4971
NTGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGT
+
!+")&*$!%))##%##)"!+&($*('"*''*#"($(!)*'+*$*"%!&()!'+&$&!#)&'!)((%"(%((!)((%$#*#'%%*(#)*&&))
@r4972
AATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCC
+
.#?2E-5$F)GE8$F65-6,DAHEA1!0-35??"!F/+/<
@r4973
TGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTCCTTTTTCAGCTCATATAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAA
+
B"F7C0:82:#3;A@,/9%5114736:;A9H8C*:>'F!/$<#6E"1GBA-:&E:%B6259;3@+4!)":9/,H$?0D8'9H#9&.=21!,B4!3*:29#0B*,6B>B!"C#(94EE0&#"4-;36)$!=0%F#,D$02$'BA(-5:H'1+-,8&9/<+4<0-?G)@8G,9*?'4<>$=<"4$<+CE!%E61&GA?,&<H5+B5@?!'3=1EH$*5?,4D:$=2;0F0G+@4:CF$<CG,!,;&9,!?D6D.H&@4-!:85:GG8*)!-G1"%E&@"0C4$"%8#C22:7!=>"&+2HA&=6007G-<:HD!-!.6<8'4<B#F!7-"(F??2-$#2F1
@r4974
CAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGNAGCCACATCCATACCGGG
+
F@3!<9-;,=C0=.BCD"844+C+,0F7/+5)D1F*=6D09A%B%:H=)?$1&A6*3$:2,#<5>?E%:@%/%H?2
@r4975
NGTTNCTGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTCTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTT
+
"'))'!#)+##'**+$"%&)("%$#'!"&"")!")#'!*)"$"$&*!"%%%!%(#)%))*"+'(""("#$))(#+"(!))!('%&"
@r4976
GAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCTACGTTTCAGCAGCTACAGTCAGAATTTCTTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTG
+
5G8/74";(!=>3!E:E/!";'-A'9B.A>.%C9>5-@9"G)-F($.)2$1=DF+61=!)@"'!$CC8@@BC0G+,6<$F/0.,)65"5.BF4*9=&2+E6B?%8A+3&,8'%EF-"=%?94-/
@r4977
TTANAACCNCNTAGNCNTTTNCTGCATTTATCCTTCGTGAT
+
%*%"%%')!(!"'&"&()"$%&*++$$)&(((#$$+#")+)
@r4978
NCCTCAAATGGACGCCGGATGANCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCNTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATNTGCGAAAAGACCGGGATCTGGACCCGTGATGGCNTTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCNTTCACANCTGGACAGCGTACAGCCCGTTCNCCANCTGGGTGCAGATTGTCAAAGACNGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATGCTGANGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACNAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTNTACCCGCCGGAA
+
$+*(&##"*%)!'%#(##%"#!)(#%$+++'&+)%($&"('%$)+'("!)'$)&(%+*!%+($"%)%$)++"&)'*)%'$###&#+""%%$%#%)#)!&&%%#%'#&'(#*$#"%&'$$&)((*())%%!*'!&*'))")!)&(+#%"))#'#"&$"%(('*&)%$*!()"$&+*)&'!+%$&&$&%$($%"%%%+(()*"+$&"'((!($*&$)"!"&'"%%($+()%!'+'%(#**(&&*!""&"$$'(&*(#$")*#*)"+!'''%"$*(*)+"%*('!&+!%!#%+*())(#$%#)%)(+%'#'*%"""+(%+$+*'#%+!$!)'*$!*&*&$%#$'$+)'*%&)"%'&$'&""&&#"*!'#!*&%(&!#!!!%#*!)#(#!#"*'$*'$&*&+&#+*#'"+#())$(!+'"!*'"+!+(+)"*('"'#$+'%('++'!''#'+*$'##'+*'&#('"*+"&#+'('")$'%"+*&%!$'!!&'&%)!'")&#%$$"#"("))!"+#+($+%'"!#!***&")$#((%)$&'$*(""++&!(($((%*!#*#($#!'$&"(+&"!&$$+()&!'&+$"+
@r4979
AGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGNTTGACATATCCCGTCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTNANCGGAAACAATCGGCGAAACGTA
+
5>BA../G.$&85$D6)-*08A766?GA!0=-/*E7&=.G*<.@9+*56+1(;*BD$$;%4%)+=702$@>B*'3F.8"E#4F=!9?2+'1,:6%.*B;<E@EH,(90-'=4"<F),&#B=$
@r4980
ACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAANGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCG
+
E7&!#;F3D/!88@=:.?;-044'8=374&.@>(G%.24#:8+G;0#4D9/@6C,DB-8G=B='78+=&@$',&:#7!/CEG&*5*&"!$8?;/8",(E3?1A2180/7385"=>G?.,$852",H)%/C<H7.,#(?>:%5)EB"8C)7A!G&'6#:"C>,,"5%%%!=A
@r4981
ATATTCNGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAA
+
6@).B!=A%D:)#?@@'?(E;,(,=!5*GC&(C64-0<@6*005'A$G
@r4982
GAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGT
+
+9-4")1=%":.."<75.=2HB2$&7::B1">=/0(62=@=9G9D8#4"@G%:A-'B&;3&@<=)2B6*,$//A<:H19@*!8>@)D:@>:::"'F7,H",D4%*H*49%6F85%D)=9C..91?041(;A4+>
@r4983
TCCGTTTTCGATAAATAAGCNATACCCTATGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCC
+
:+*5#4!6HF$C.*D#C"<@4<+(6*>4:12.BE9,BA,015D8"E=A<B<*83,0F&(8*7.()*/+H*CGC')'240#,@47;,/;*)(7'&5?C%,B><.096)3?
@r4984
NCTGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCT
+
#"@$$'D*9B5D%9*GF+':C$.853:>0>&B1&,6H$EH&!/.583.5A!<%%74"0!%,9B0"0(+A"4/$@8>:''>)$97F46'<G(C(,ABH0.>*7#%=##@F17
@r4985
NCTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGA
+
"&+()#'"%$$)()%&(''$+!+&&&&'!*%+)(#(&'!"%'+*(&&$#*&&!'*%(%!#!$)%#%*(*'!"")%'!("$'($'"
@r4986
GATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACT
+
9/$63A&8&,,75:5A.A'H!/G4E73$98&9&H.7,"58C,=B2!(9F&;*,;"A$H0,0H#<:9?-()+<?74BD=#DA2$(+A9<25D1$4FDB#;!*,=;B7(D:%@5::
@r4987
GCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCTAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTNCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCT
+
,E57,G&/<.475;A&%D&'%"0F86*3>F'?E:.965!9(6D8E8*7!7B#>!"$%(48&=.264@($F&94C:"3)H/4$6(6,30(E2;EF5G=,68E7(52D@B#"9+H.3<+AG!:B$$7(2&,?3!#)E3;15656H!-.;819G*57C/:,*-1:A0#&
@r4988
GCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGNTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCT
+
$<F.HF/4%/>-B&<CAD-D;8/-8*$%>@BB9=DA+C,EB"9,2#220#&,&E5%=9.+3=2F>"7$3=D>8<+)D,&4G&10G3:;A$16%."!80G"<12#:-+/+'+&0$"
@r4989
CCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACGTCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTA
+
#..$/;/G"B0,*"?EC$8,!*4?F?CD=?93)!/H#',<AF2!-8;5?+4<>20>1"3;35*5("!#1C1HD>1A61!.$(E&>34+<;/*)+=:)D.D))5D=E>'=",8)F+5B-%.4>'FG,D95EE.!*95-2)@$(29$A.;(?7"G;395@+./0$9#*?+1=<FD8,947?4=G:-#B1H(
@r4990
ATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTC
+
19G)?7=?./%,"39?1'%H../%5*1E,./52187,'86F&:&1"B(4H*5A?BH@?>@))77/G!2+CH7)3'B5D;*0=:,9H7.)>
@r4991
NATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCT
+
!3?$2=DDD&/(;>2D(8-G))=6CB$12*A72(*7*B0;H/8,A%H2+22"<<!2C$';768$$$A6$C!-<@(:
@r4992
TTTCTTTACATAAACATTGCTNATACCGTTTAGCTGAAACGACNTACATTGNAAGGAGTTTA
+
+0&>-DAFA//2(4+;H(H*#::5;2,=3;'?0">%3%,/12B0D&&HC(<4&;DE&EDFGF
@r4993
CCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTAGCTTCAAAAGCGCGCTTCAGTTTTCAGGNAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGAATGGCCATCGATGGTCTGAAANAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAANTTTTTGCC
+
-73=(260<CDF;#B5<?-,*?D0;#2F;>8"6#?7!6507*)BB&?D$H=F*'@;@?E*/G+@1C1&=(+".+5""9(#7>4E-;,C;?G1/70):;<1677"03002GG%EA;1+.'-66+95@#!8.A-90;;3@#--*-/>6(H-B.$3/9+4,?F.H63D%'.%;C7=09!77;&0!=3-(-02#$*?>F*D7?*(,@A+9/CC13+71&;C+0D(&;'BF%)(D6%@%+&:A//D>F.4!C#9=C+D#!.!G!
@r4994
CTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTG
+
H%01;,+.9H-<A/:-#7';1&63<57=E;1F#.?@.22,-H(5$7.-DA+C3"%FB!!:@&GF>A6'2(G.D6E!-F*A7E!$+48-&2&
@r4995
GTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTAAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTNCTGGGTACGGAAGTGAA
+
<;*/2!-#/=(>-FE!63HC7<G%"4.G-1'+4!F%5DA=07@9E;;E<#0G+C<1/33H*+'>&"8!GE,%7%)%:*BH41%-B.5#-7D=/!H'A@H/$9>+41H%8:1+?H0"24+=9B-93H,!$C5
@r4996
GCNNGGTCAGTTATTTACCTACGACAGGACACNCCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGA
+
%"%)(+&!$))"$#!%&'%+#+%"&"$*""&&&'*&*!*)(+&"+'$&(**"&+"#%'%#'$*()%####+(*#$)&''&*($"*!!#)"%*(''()()&%"('*##&#)"'(&**+#(!&+$"'&&)'+""#
@r4997
TACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTG
+
3'-@B.F922E0"5,;GD)'>5-8>6'1-=B/G0G9)8A'C.)8.EE
@r4998
GCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCANACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTNAGGTAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCNGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGNAAGCGCAGCATATCGCGCTGTGACGATGC
+
B9H405?E<6&<!04BD!5!1,B'$?4(/F2F7>#A)G/"1(45'7A+?$!/G4<);7$"3293?&19=9&9D-*()">;$G,F:&?DAA159B/"0/FG,3%D$>DG#2<-B*?9(;(21)%;C$=6,;4"2+%?DH-6=A6F""#7&(-3FEH'0+#8&;8>/9#'0H7E19++:#D@;@<A=04,>=(.(9=>#BC20=HG-.30:&:*52C!D8CF//%!G%+-&<-1D06<>6?3-#"@+1/>3794:,2('-".HF$:=*3'0+GGD@4$G-,-@.9=-2*B(B8'9@+&*###CH%,(33'!=).1/71-;4""A@DFH7**.E%!D&#<09>&1;6/())BC&9>H7.6!+(@D&A"G=?=:"9"HA62
@r4999
GTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGT
+
*5;-*E"*!*B1+!+/*,)?;&:>*"17F5)+51D-@"84*86?"7
@r5000
GGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACC
+
A69<B=)*)<A8"2&.C:HHDB"%&!&E/3*873H)&.3$G9924(:G+:3;840)7DH@96(%C<&>83#5*::HA+
@r5001
GCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGNTATCTCCGGCAGATTTCCGCCCCTGCCCGGCCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCA
+
BF!#H34F:4!B8*"5AE4!G=%>!<'7,7#63$&H';A;&18F.!E=>0:B:@5EB,('2<G43HG$-*9434?:23.55>F-F.$+,+.+=8D50A*.F,C3!":2F#@H1A3>??1;38(:&(@9%&@876B9#=C1'>F3E<"+4*<B@+9$7*5)92*/BB=7<:%6@3"C=B0(G;+63$EF"<!C6)
@r5002
CCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGNCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCANTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCA
+
3+;>3.,+(+-;5>;-+>H')-::5:D0>>19!H+-D#5&%/58F3/):/!(F0$F@B&9:;*5,/#/;!299'#FA(.+G7-0!:+<5B/B)C;!/FH(&HCE,<%A9)H69")>)/9?=/$+>3>74567%3;@5=A&+='7*73?1++$&>B"$(C9"@!.E"29$3&6;>6)84-9&H2$=@0(&1D=:H#(BH3,)?*87
@r5003
CGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAANCGGAGGATTTACGG
+
C=#4#<1=F+4@<*"?F>;D=!2=;A89&(&=B:#2A;A:C0(65>2A+)?H%.'=63G",(:@/E'7
@r5004
AACCAGGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGN
+
,(BG"""<84C%/$43+48*?3!E@+D5.)"G.>2@&A)%4@,B=01:9!D)CG.22E</
@r5005
GTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTT
+
(1A/3=64A",-#!<<%C*)@<("A55/77-D61'@95,3
@r5006
NGCNAGGNNNNNNNNGCATTNCCCNNCTTANGGNNNNTCTNTN
+
"!$"#$!""!"!"##$!$"!##""!#$###!#"$""!$$#$#!
@r5007
TGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGNTTGATTACGGGACGAAAACAANAGGCAGTTTCGAT
+
H$&GA1&E<DEFH%*#6#@:A<,)'B125?!!#<&<:B@F317"(>(.+$!<%";);D9!5:.#<3B19(2B.F:7
@r5008
CTATAACTCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAA
+
.7&"A>5:/CH$(C!0*9=<F-D>&DH+"0>3"=646H7):/C!8=&.3?54%3CA/('<7D+=;$#&+$<#99#"8;.4&H3=A865.@;*/9+@E*0=#1(3*--#C1/5G:<8-<;*.*5
@r5009
GCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCA
+
@&E-F5G3?G8@"C,E=6.:/606:"80<72,,-:.G'23525&
@r5010
ATACANTGGNTGCACNTANANCGCNTNNNNCNGGANGGGCANTGACCAAAGAGACTCAATC
+
%#$*)(%&)#(($))$((")!*'(!$!#$%"!&!*$'$&!$"+!#)#+)%($'(*!*!(*$
@r5011
NTGCCCACAATACGTNTANGTATGCTTTCAATCTGTTTGTGGTATTCAGNCTGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTNAGCGAGAGAATAGGGCGGTTAACTGGTNTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCNACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTNTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGGAGTCCTGAA
+
('*(#'""$%*$$%('#'((#"+!''%()&*"(!&%)&)!#(#"+*+#"'+((!%!)#*'+""($&!&$''(+*!(!""(&##)'&(+()*++#**++*%$!$')''!$+($!#*'%"%%$%"#!(##)+")!'*)+)++#+*((#+%"$#+'*$&(%'&&&*#)"$($"&%*''!%*%()%&**$++*!)*%%)$!!+$++'&$+'#$"&%%!'##')$"$%"%)'#*'*$%)+(#""%$%$**%$''##!(("+#&+++("")&!((#%'#))&$&(!%&+
@r5012
GTCATCAAACGCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGANCGCTGCAACTGAGCANCATACGCAATCTGCTCCGACGACACGTTATGGAACTGGCNAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGANGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGC
+
+"#&%*'((#*+%*!+$*$'!+!($"+(!'$%(%'))*#*%*$)*("$$*%%+)'!*$"#**(%*%*&%&$&!+#)!'+"++($*)(+*&(*'""!+++(+)+%+(+(!#%$##&+%)!("!"!+*#!(+'+*"(&)$*(!+(!'!*+)!)+'&+!+"!%*!%$)+&""#%()+"(%#!++)%''#$#+)#&#+%#!(%'%!+%%&$(*!'"&!"(*$%)%*!!+((*%%%&$"$('!*"'*'"*'!#!("#*!"("$!)%)*)(&&"!(("'*')!+')&
@r5013
CNGCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCNAGCTGCTGCACCATATTCCTGAACGACTGAGCAAACGAGAGAGGTACAC
+
*)%+!!!%'(*$%"&#!")$$&#*&'!%%(*(*"*!++"#+#!&!&#))"!(+'&$+%%%+%&'(%(%)#&%)#"!!")$&$#+#*&&#"+
@r5014
TTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACC
+
(60D-H-G06=(@F2F(:5B1'0$%"@@B%.3*:@?'6F75)9H1.$,E./>39%)H4.)/;6B:<-BA)/&EB>/*8310EC;H/AD'=;6>$50416E@-39?8#=DEC$$49+8';:0%"21(
@r5015
GNCCCATNGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGA
+
"$H5E'EA*D30:)">;3'HAG03HG2&.$$)6'$9>G)@/DC<)"/$-9G=;999582'$-(%;9%*F=+8)@5>D02=(3
@r5016
NCGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGT
+
.3.#624>$6;<="H13"#1-%>CD8B@,&+53C8'2%/2,G$
@r5017
GAAGGAACAGTATTGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGA
+
/A=.5=%D&:%?F7*2"=7DG4!B*,$8."F8"FA%?"#,&$&F&4+"72;@-HCC
@r5018
GCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATNAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCANGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTNACATCTGTNCATATCCTCACAGATAAAAANTCGCCCTCACACTGGAGGGCAAAGAAGAT
+
'?9F+-$&=C!%=5E!6=(B"(D8,+*H<GE;,)?BE#.$59265&3?H7)2'G-1!9*'7349,4%:+A8-#+H;$D$9@D:=;/'/,/D2.<A'6C:):A#G,71"?;$#6H'A/1C0B;"#A;=:).7B'$H7EHFE''B%%7()"C4-<%<F=:H<6'C+5,H=+5>771/3*7=<:)E%>,8'@E+$@$<6/,/&$@
@r5019
NTNACGCTNTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCC
+
$#!!$*'#$+%+%(($*+"(+!*+#%(!+("%*)!#")&)+&&+(#)(*("'$$$!'%'+)%'&&+%!+"*)
@r5020
GAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCANGGCTGAAATATTCCGAAGAGGCGCAGATGG
+
G5.E%B/8H<E8G@*C$4*07'A*52<@"F#<3+?!5F6=7>=@8E<D2HH,C.$F$81(-<;5EEC?>=2+7)='>F>H&=5F3E(.*DH6?+1E03B
@r5021
CGAACAGAAAANCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGG
+
,DE$($62'"B3<D4)>70'BH8AA?3("3A86FD23,:9D->G?2(',4+7A(''G5C,<*FA!7,%+
@r5022
CTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTCCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTC
+
%:/061%--;"78"GF3+>+'+C'(!8F1?#BG)1==2:A/1F)).!:/!256"D;C.49568"D;$;D:9+7</5%4A>*2#5*9!D-3%HED"01!#!&">55<:*B+!.02@%&*)E9.(,&"?.-%>01FHE#,
@r5023
NCGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCNGCC
+
/G886C8B%3/;7,'<3EB",8$62?-E+B3D(-!H80;#+5C43;9-:"D#?D#
@r5024
CACTGTTTCACATCGATGATCNCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCANCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATNACCACCGAGGCCAGATACTNCGAGGTGATTTTGCCCTTAATGGTGATGACTTTTTCCGTTACCCAGCCACCGTTACGNTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTANTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCG
+
:+#H**,H?FAE.@*GE./>.2+(59&>/27:9/'7=;)1&2</E8668>-1$:4D@B20-#=85::=51<2BGG@C//;A1509&-@6"A!D9$/B@"&H9"/EADA:=22E1@.9AD51-??1=+,)H",8#*1DE-AGE*$H=A7><,,$E=.0<280<@'4(#;3B2>$'F=$9A(%.E2&=513:*@/*@3FC+0/G>4,@1,%;#/!30*5&'"&+2(6H9<B#<4D')+)5=)B,71G.-07F-&027:19#8C(5&'=@45:(E9<,><<:B.)."H)1.@8+8G/*D&@2@2#%)&-=C>(H(A8@FCB,2@$&96:G96%!4:/$6!GF&=./2(184#-,/4"G>@7/"*,D%@>EE*('7/0%/$
@r5025
ATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATC
+
(A<#(F=/5D'$?!E(A+"?B69(F$2&!098FCG%$(=>.A.3!A.'35-C>8/,CA$208+16B..+*.***F;%*
@r5026
ATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCGCTCCATTCCATTCTCCTGTGACTCNGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATANACCTTCATGGAATATTTGTATGNC
+
6+.&*@2C(*G:+$6B088/9&/*C,)2/A&;5!%8$/02'4>7#*@28-5'/;"2H,&#6=?6HC%8G2AA53HF<+)7#G88E(=<,7*9B#/A!=9>H@&</E683,3/<>/HF#+=7!9"6F$<%E*H2E14GB.++*05:;=%!;033;F,==;B!3C=A,#7-,FA-D"%C!DF1)(9.!+-01A=&5%F87&=?*D+GC?9::9@H!G@6GF:BB2GHC$!+0!@B=&F8?-.()167;H!F%BA7468:>9@)5*;@-+9=(#*=%DH+::"?69@--F=!03";9));?G>'%"!73,--B76C-4;@%FH')009%A="<&31G02.CC
@r5027
TGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGCCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGT
+
7@<7?D"<H4:;>#9,!AE)#+2!0,%8H#5$:B:<A:DE1$EE;4A457=;9=G.8"55/)FA5BA-@*:%!6>"D1'=542>C#8<;!A<&'6)(<::/&>E74&H5G/88#-2:@8&>8.<!.BC"1C:#.'%-AH8GF'-8$06!C93@5
@r5028
GAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGA
+
=G&?!:E4=7')F3;".ACGE:F4?!/!#-.B*&2>B0H$G5.1,9($0
@r5029
CCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAA
+
@49(/58"7C>597'@C;&18;$":75.85G8FCHF;-G+@<ED=C!EH*%05:!B2044$)3$+:%)>,9H&4;7>!((2/.2+)?B6B5",0$H&8"F$B<6=
@r5030
GTNANNNTCCTNNNTGGANTANNNNNTNNNGNNACANNNGCGGTCACCNTCGN
+
"#"$!""!!$!#"$$#""#"""$#$""$"""!"!""!#!$###$#$$!"##!"
@r5031
GGCCNANTGGNNGGCNCGAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGG
+
$)&&"##*$)%#%(#!#**'+%))*+(#%&'')&%(!%$!('%*$%)&)($$!$$*)"")%
@r5032
CAGATGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCNCCAGAGTGTGGAACCAAGATAGCACT
+
!A94C>F#H424"D7DAF#,1A%6B.2G0714/E/DB'2,)7'G#!8D4G+$7BBD*;HH,-A<6-*.E.+$4,*9.),25CB>C&&FB=#40F.@<;0/9B2C:..D)924F%@1?'$2B<;>3G;@#23"(BE:;6909+D%!.@"B8=7-?*-(:31DD!#C$E--9::=/D@"5H(*$!*3)=-4AC68,,=5!EB$1-()B;
@r5033
NNTCAGCCGCTGGCGCATTGAGCAGTGCNGCGAACTGAGCGCGGTGAGTGCCTCCT
+
%(*+(%*+%%(!#"*"#(("#%'!!$!#()((!&$$$&#&%*"#(+%+()$$%)$+
@r5034
CATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGT
+
";,G53E8D&5@%993"),9;6%3?:7)H*#1?40)A!@+8"
@r5035
GAACGGCTGCAGACGCNGCTGGAGAAATATACCGCCCGTCAGGAAGAANTGAACAAGGCACTG
+
D8C:*A=D9D7)@=<(A(D)+80"<!$!>")>;H6#A"?00(D1-@%A:DFB70F;=/)#!/#
@r5036
GTCAGCTTACATNGCCCAGGTGCAGCACAGCATGTGGCGNGT
+
:,9;0A=@A@:$=$8/.(H'1D*E/#.DB8(/*57C24+=;&
@r5037
AAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAANTCTTCATNT
+
*7)'!!&"@+:E:@4B)H*CH+-@9)+;?A4@=&/E+?@%,AE,,.C%F'!>,+9%1=B:=BA712:%
@r5038
TCAAATCCATGTGGGATGCGGTGCTGGNTATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGC
+
/'7;.)!6<+7,?-4)-H>&8*-%;H7)-*)=?!0B70-$$?*$?5;E0;3:D-A8@H/&#0+)0<0-@::%4#@>EE+7&76"/D!'CE.C%C4+C;AD6),@%,3/E)AF(40/6CB!?9:D,9)<H>E&"5B59D7;0B.(EB$D"(
@r5039
CGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGG
+
*>)A=B5/'H<>H,$H+F#&=+:<7>=B5E-=:/8<HF+(%#$73!E2<=#-GB1HC)8%@?138,G"7@DD1BF5@3A/$79A"/;437.?H;.AB>$C<.<6,$.=BB"(!?#<3!$*E&G,7B/&<,%3+0/F:4,=8B;,D$1G)0.0BA(!4*E:<;&='GE7
@r5040
TTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACA
+
&H<#1-$$+;!,5'":E@A.21$3H<A2<8,=F3D07;F,,
@r5041
GTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACG
+
FE6?C+*#="7A1$*E2F61&>"BC?4"6A+>;;7A9*11<?2"1#!3(,G#>/(>#/9
@r5042
TCGCTCAGTTTCTGACGAAACGCCGGNAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAA
+
?A-&GG=601'*(<,(/A(G;G20".0)AF$;D4?(:*:0/@55H'!0E?:B";A4;8&*G'BD=2!?:.9CB95,G!;&,;8:+6A99/05HH@
@r5043
GAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATG
+
7$H:9:?'(>>"=:.)>"@;7)D/)"EEH?>C8,0@HF":E&-<%:9@?0>#7/G.A@5.1;$1'9F1"/3AD*+G"),/H?/)?+>G&*0:.?-G"3";H@:A9$C0'<7D>-)6="02G&1@:1&,>?$7;H/;;.<"-.CB4!.D3@?3F1@-DG(8=$>&'D</:</'>7FE;"=$A*/*;D9>',#/%0*$:
@r5044
GTTCGTCGCGGCTTTTCNGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTNCGTCAGCGAGGACGGGTATC
+
5D845>F-G<F7G2G%",<"6=F;4#<75)H#=*!!5;*>BH+(?(53(8,D1#(G/1>?/+EA!#.;(C8,!!5G'+;@-52;=C?<7/;F@129)#%@)*.1*)77B=?E'>1%@CG"+B=AC8:1%$9B<$A,'@C3+5+6BF"4A;D=H60!
@r5045
CACNGGCAAAACGGCAGGAGGNTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGATCATGTGTAAANGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTG
+
AA1G#1B0/(AGB4G2*/-(8--E>A2.6*DH5FHFA.8.@9#=#A2")2531&?,.<A7+<(0#%C91C58!)"/9%52E9",1-=CG=:".8*E0**)""8+H!/*6/)&&"6)/2HEA"ED(-@#'>'%9(H
@r5046
GTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAANGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTNATCAATGTTGTGCAGATCCGGT
+
&"(+&("$'("(*"#!'$+'!*+'!#)+#!'!""*&)('%+#(+$"&#)"*#*'&%)"$$!')("(&!"$$%*+'!%"+#*'&'($&!')((%)$*"!!#!)#!##*)*!!$+*"&%&(!)+%)&)!)$%$'
@r5047
CGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTANTCGTTCGGCGATACTATATATGCATTAATAGNCTATATNGTTGGTATAAACAGNGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATNTNTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAANAGAGATCCTGTGTTGCCGC
+
$)%@?-0'0(?:0%'-H::-<./=(5GF2H%D<?3#B(AA9?+E0DG&8..4B&6*?>1D>#E<!35+<D@=B),"$-0%7DA2"#)?;.?8(>$@/E#<9&?1A)7GDC.(E?D008GE09;2599$0!<2?.9409(1(@F&)*A;C#534=;.-6019/H:F@?@+0H$)5%:DF=D(E"26+D,:9)(48@!>78(+04;:CD,%3504D"$H6G7B=172G5HF>#,FFC,1==1%=,A1A9%2,6G,-G20!C$,+7==$3<#2+H%3CFC+,6@$37=C.C.85(2%"0HG.A6B;(74$>*A(G>%.A0&
@r5048
TGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTN
+
&H,))%5'6"1+G8!6:1E"6*91&:#-+,$"/042+%*)
@r5049
ACTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTA
+
)!#$&#+#&"()&#&+)''''&"$'!+#!))+#!&+%("&
@r5050
TACGATGACATGCTTGTTTCATCAGGTGTAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATG
+
<&,9,15$3=?.C97'.'9CF/=$#F(H<D=.%%*(5,334-0G,#0"G52=*=<=>E41G8%@//>.AG1H,?@$'&E<HD@?A9/&7.*&8F+$=)/%%9@7*>->C$"&G4)-''B?GF0!40/>(:<E%6D..+$%9:$G5&"0#06H#<:9/:$.;:9B:84':.A$F2E5$1$B"2"A",8#=)=4G"#;D9/4'1=2@";=<2!+?1>4$4"F+9G?'5?B1/!74>G4B*1*/G#-6<0.3A26,
@r5051
CTGACTCTCCGCCTTCCACAAATCACGGCGCTGCTGGCTGAN
+
($+++&+&%$!#'%''+)*%"'(+!$+!)*'#)$($!"++*'
@r5052
NNNNNANGANATAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTT
+
(!"&#&!&#!++()#&%*""(!!(*!!&!)$$%$)+$!#*(')"'#$$(+*(#*()!)#(*
@r5053
TAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCNATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACANTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGC
+
/$AD1HB.D>992'*7*)1/D1$H#;.:/,G'75.@<.=6*,C!?$A>(?+!/D=&,:7*7C*9006%#B)65%-1"G(,&'=5EG2!?:1F%2'9?"-AC!"3<-*1=.<B(6:%)6:G.(5(=C;@3)''!"=?GB4C7E;+6<3&8
@r5054
GCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTNTGACNGTAACAGCGGACGACGGCAGTGAG
+
8*@5G,D6'C;7!8':D-+.49&(=@BA&&>;-#6>0FG,%B&C#HF1;@:B@%3$7C)@!1&D53&)2"E1#".667*FC:*>"<!7)2F>&"3!D9*"7>/">*)!
@r5055
CGTGGCGCTGTACGTTTCNCCGATTGTTTCCGGTGAGGTNATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGNATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCANCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGNGCAAA
+
6="@!?*DCBH(),"/=@3H4:95@)AD;)*58G78FH+=7=4$H%49-'E!B?6H;C(:#G2(@#==5)G&)8@$H0CG*#7>9D.<">,E0.3DA')=+C&;(HGB'+A9'++/.5G-9E169,7-,=")<;!581?+73(3D6,!&H3+F@A=>F1'!<:"831E@")77#CH=H:-:2H64.48'H>2-A?75&!-23C9-"38G<-)(D.=+?!:3:5.#)+C!9#5D0*3&1#95&G#(%-#<#<(0G"$A.1*"E7=((?#&,D;<
@r5056
TTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAG
+
40G1&4-"&9#/91.)4&&?9(@CH8F,<7F=&FE*=8C;8+$85&@/0;=:>H!3)F7.#65G32;&5=%';H(882/<.A0,B$8&%-H*24
@r5057
CCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGC
+
+($)()#'*(#)&(#"#)+!&%#!""&+(%!'"+"*"$%)"!*'!!$'&"(&
@r5058
CGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGC
+
;4042C.'?DH*#3#-5$.62:467G&6.73=,6,:@;/E;4#B6%&..>AB;>1D>,G8EEBG
@r5059
CCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCC
+
$A8?!2#>&C*,@D%75'%G6.0-F#C;,>6':%(A<'1<8#D=&0$14.A/7E3?@;H('B%%A,75:2(2
@r5060
CNNGCGTCACTNACNCCGTNTGAGAANTTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGACTTGTA
+
)!"&#''!'#&&)"&'%$!"'%'+*##*("!%)*)+(&!&+)'*+&#$)$(!#'**&%!&+"+!##"&%*#"'#('$'&&&&&*%#!)'#))+++'("#"(("'*#&)&++(#$"!)(()&##"+'+'+&$+)(!"#!('&&!'''%'+)&*"+$%'$(&*!'"(%#$
@r5061
AATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCT
+
++*#%"%#'$!#"+'%%)+#"%*!#*+'&)*$%)&(!!(%#$%)&+*&!*++*
@r5062
CTTTATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGA
+
)!6*(#C15?(*;%($1B.:2"*>;9)"71/E2#8<&?"+*2*#5@:%+$H
@r5063
TCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCANCAGAAGATGCTTTGTGCA
+
A*%G2G1)D55.1/G;0>H=H':G;1>9+80E3-BGB)5$G&1'9(#F=?HC:C)3*0:9=E!$5/EBG-D*:4:#943636'/B/7+D7+F(D--224%#5>4)2
@r5064
CCAACAAGCCGTNAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGGGGAACGCTCACGTCTGCTCNGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGTAATGCGTGGTGTGCAACC
+
1'$*8!E+7(AF?E9*@D+-,=,$!?4?@4%B%*FF3&9;+398-;.:G'6@A-A)4:F.ACE#9000=13:$?;;EB%9A1-C!*E.3"':B*)6@2).5AE@"/35=G%8F6-//)8@9/%5F7%*!7=!@*6*0;$4$*(=C9$48,?36HG7F/!@#6&0-9#?H>-#G
@r5065
NGANNNGNANGTCNNNNGNGCTNNNNNAGNTTGCAANTNNNNCAAANAGNCCNTTAGANCAGTANTANAGACNNNAATNNNNNNANCAANGGNAN
+
!!!$!!""$#$"##!!!$#"#"$#!$#"!#!!#$"!$$"!!!!#$#$"$$!$#$"#!""!#$!$$#!!$##"$$""!#!"$$#$!"##$!!!!#"
@r5066
AGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAA
+
%2@>C*D:$(%0G+$+8@)FF"(,0F'$";.7!:G6F<*+?&G;%+80D:@0.BA6:&
@r5067
NNCCCTACAGCNAGANATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCG
+
(%,1&0#0/;-G>>$EHC.8D(C%?#?C1F3,%$A@=/H+'5(4!>(+H46$2),;;'@F!=A+'?/E=C(90
@r5068
NCTCCNACCNTGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGNCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCTCCGGTCATCACTGTGCTGCTCT
+
%*'%)!!()(&%#)#&+!(')!)!'("')&"#!#(+(!"&)!#("!*)##&&%$&+%)%#'$&#'##'*$!$+"#))+*"%"#*'%)!*"#"+#&($*!%!!(((''$'%)+%!$!"%&&%)!$$%"%"#
@r5069
GTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTNCGGGA
+
-=A:H+<>>/06C$:-,:%*5)(5<520.)5>4/+H;5.2B@+9GC=,%*?3<"(?9*<=+16&36)
@r5070
GCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTG
+
/(21%,;GA&74(?,.**FAG&7C.))#?B-H9'"<8&&@EHE%F@@?D'83=?>+2E?,A,DH<;:D)#-@@680;".6??(;(?=033B:!FC66#2?*22H59:H'DH?05%*0.<=6B(*+D'3*E#F)D(/!.4
@r5071
NTTATATGAATTTATTTTTTGCAGGGNGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAA
+
!/$6#$6G+&/6=,)84$-'/".8D$,<F253*!AG>+1!H0@$'8G?/>50B%EH!C9>@?4.=+33)67FA1F"(EC7=@.?AH7>6;*)(%
@r5072
TACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGG
+
)3=<!#5%@(2-A%!'1*(A.F*D!,$G%%BB;-#)(2!&:;/F
@r5073
AGCCGGTCGCAGGCGTCCGGGANGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTG
+
F*(C5"%#?"(.@;+A=/;1((B".'.BE>G,:':#"/56&?7C$#2E@"!%31?84DA9=5/D0A!*/"5%<#73B0$C;<&/FA26#+4#4E3@'*?#=*
@r5074
TAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGC
+
F*7E0&:F?B;F1(-'5>3.3B&*/:2>$B66HD5?-<$3H1B,'EA*'FG*(C2$@.<4!!9C
@r5075
ACNNGGCGNTTGAAAGCAACCTTCAACGTATTGANCGCAAGAATCAGCGCACATGGTACAGCA
+
'%#!%&#$!+&&*'!"('+*%%('%"%"$%&'(#(((+)!!+**!$%+*!+&!++)(!$''$)
@r5076
TTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAATGGATATAAAAAAGGTTGCCNAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATG
+
/7/6E$);5,3G39(6;<;+G8540+&,0,D:C/"//.>;"+,*$E2@C@"068,&(7#+?F-*F/*(AF2C9'<A&%.C!)!).?533->':!6$@A*C354A242&4D9)B(9AG8-9>
@r5077
NGNNGANAAGTTNTNATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCT
+
$$"$*%"$(#$%("!+)*)%)!#$$#)'#&*)!*$*!'"$$)")$#"()&+)+$('#*%*#*%"+('
@r5078
ATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTNTGNCGCTTTACCGCCCAGTCAACAGAAGCCACGCNCATTAGTGAAACGCTTCATGGTGAGCGTGTTATNCCGGTGCTTTTTGCGATA
+
+)#"+%")"*+!%#+'(!#(!(()#$*$(!#$')$*)%+$+'!+#+!("+!#')'+("+(&'(+')'$((#&($+*'(&'$%$(+'*)+#&#$(*+&'""'&$++!#*'$+%(()&&!%##'(#("
@r5079
ANNNTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGANGAATTTGAA
+
#"$"+*(")!%+*")&"&%%(+$(+))*+)&*'"+$&&"$"&$(%)*(((*"%*$**"#)$#$$#+#)"#*%)"''#(&#+"
@r5080
CNTCNANAAACATNTTTTCATCGCCANTAAAAGTGGCGATAGTGAATTTAGTCTGG
+
$($#$!#&+*""*#"&%*!*''#''&$)"))+#%'!$)%!#&(')%#%**"!%&!)
@r5081
TGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGAC
+
4%9FG29F3==,6?'"*4&-8E85"*9*$F0C)4D1HH+-.#6@38&"#D+<<;C3=3G07(<<9>>C,:)56(G!<3B
@r5082
TTTTGCGCCNCCCAGCCGGACCGGCGCTGCGGCGTAATTGA
+
:.:65./&5'9@:@9#0C66)'.)H=6/<2>4/B(FH)@27
@r5083
AATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTNATGAGNGCCGGGATTTACCCC
+
17.!FE;B19G(;-!?&<63/EE.>//H':+#<(G<'?@:'C:F>$3=/;F-5B)D:.EB>!9)&.8-/H$7?EF(8/1F
@r5084
CGGTTGCAGCAGAAAACAGCCGCATTATGGGGATCCTCAACAGTGAGGAGGCTCANGGACGCGAAGAACAGGCACGCGTGCT
+
+%'%'+'*)$'&**""#"%*%%))'!%%(&$&+!$')*)&)"'*""(#('+(*#%*")'$$%)#)&(&#)'*(**!!#*"+)
@r5085
ACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCC
+
79.*2H#>C*4B;5&.?6#G?-,-6-77%81@47A;A-/F@"7E:(4&+;;,0.,.0'C7>EE-6?&39$*".H2,9D0H:,6@
@r5086
CTGATACCGTGCAAAATTATTATCACGAGTACGGTAGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATNTTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTNACAGGNGAATGG
+
3?:?1"E*8=H!0+.,2;A,A@>$&H();5=;$!FC?&G$<06+@400&/-'CBA?(5+F=/E4.+D!+;B")0C4&80'@3'-$@A!->F,@$-@G59$88("6'":4*0)E3('"C,$2?:EGG>88-#4A**D=!809+;(>D#>$+!+9>'2/+/H4B<%5##F,HD##;.=/!GE<G@'G*%H0!>%!6B
@r5087
GACNTCACGAAGGTGTTTATGTAGATGANGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACC
+
=%2!<F?41>>5?<G>5?)D&821H1HG9*-$,2:)>%;A.!;!EH!2F,6&<+5*34"(/GC;$6??0@9<A+3G%(09=&FD#083*1#9#//C972);'-,':#>B)EG+73/"2'7G"*HH,0+
@r5088
TNATTAACACGGTGTTATCGTTTTCTAACANGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAGATCTTTTCGCACTTGATCGAATATTTCTTTAAAAAT
+
%!>9@=9:=6:F&?(5G3$:59)5/#/1">GA=H3B-.+H7-DE3E*62193@+&:,((B>*E4F!++258.G'16G!*+3!>=$2;.B5+7%<;%2E0.7A&5"3=A(-!H=/(//391H93>F$&+2#650:6$E=,B3@833%%-7(;DE#
@r5089
CTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCNTTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGAC
+
'"4.;%$1AGH7'GC,1,9#6+7G8)H"@31";6?7)>!.D4#%>>:=,5#G:<6-:&/.9>D9E+"/#HH:$-5>&(D-H<@&GB0F<5G,#/8E-$!H2:=0!/=:(06+G"79H4%)7E,&@H!.9CD#(')<5;H*!.%60DC##E<D8-%>*=G*/BB"G@);2D-
@r5090
CTCTTCGNCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCA
+
-5F*0$25>@G%;.1D+!@$33%-$F5CG,"@*6CA6'2<@5A+4"G-<7C:60)81,9*E+:H
@r5091
TCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCNGTATGAGGCGGAATATATG
+
>,,9!%/C--6*&0*F.:4&A9,)A0GHD8?>.HH50#'729A*19HB/)6@/=-0+8%--7#+(2$?3E0!.F11F7H&($?A"'A.-'<9$!:7<
@r5092
TTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCG
+
8E&D?>?;/49DD!=!:/!&?(6AG#:-2%H-,.=B4'%5)A%4@2-3*/$-*+B>#D&>7!6;?37;,D"34G*//+>A!E)EE&'B=8-EH%C#H-<,?8EAA'F/$>%8A%3B).(H%C98A3CE':"-1B*7?D@$<;-$F>;E36@8!9':!/4H;('E)/>?EF%+(%=H(1H>H.;:>31B%.#'3
@r5093
NNAAAGGNTATCAACTATCNGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTG
+
&$*1(?6%3E5)"F7&>$>::HE//#($9:<<C86@C%()D5G.B4.F#'*&4<!D6@#2=%8
@r5094
GTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTAT
+
=>-BD'49?F"B*E6!)1%4BG*G$=BB6,<A":<&"!-G-*49>C775D5B4-4*()?.)G07*/$H;?/C$-;D,$)#2A<-F2:9/<D))DF7=@:>BF24>"8<<)D.>0?,G":3/"=7+G'0:4H438?H,73)91-6@$=6
@r5095
CTTCCTNTNGTGNGCGNTCGACCTCTAAATCGTGCACACGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTNAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCC
+
*$*(&)%**!*(!'!&%("++*+*$')+%"+"+(!+)'*%!'$"+(#!*$*($(*)(&'*"($(++$('"'%%''#&(')"'%""*%%*&"'#++)#($)$#+#'&'%($%(!$%')*"'+)**%#*'$+%$'(!%($&+++%"'$%*'!)%&))'!+"""*+&
@r5096
CTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTNTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCCTCACACTCA
+
7:!.",GF02**'4B+/F)?%4-6"C,DF11.>268F:D697#7<0@G8/)#.F/(D+H,4E&@F3+@4;C.00'@-DBC6#*&*GC'+&76$0:;%9G*?/G?>//H:A/(@"E.F>9@977!==;=/-C3=>0:5%(/H,"6*(FD6(=./'A>@D8.7*&)4'A4H:.D@E0.8)B=!0?
@r5097
GAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTNAGTTTCAGTATTAATATCCATTTTTGATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTT
+
#2ACD(-A=!>:E+1(=G220/:(:!6G;F(9):'*+*DA;&!4&-.<0-=3;6/!%C+8G7*GF'B@E.45;<,7;1,92B,9."+=C84C2.4@B9:CF@>).?5="D!8B',%4=CB?%$D@E=='!H$$?*5'1(?%;57/,>A(D@=DB191-0)!@E0,#>0=">+6G,C&E=>"7G779@5+,C1.C5%B!0HA*+5/?3/%!C=/2B98840F30.#4A0&<"<D-D"A
@r5098
AGCTGGCCATTGCTCAGGTCGAAGNGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGNATACCGGTCGTGGCTCTAATTCCGAGCTGGAGTCCGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGTCGATGTGTCCATCGTCGTGTATTNCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACA
+
;5-+3#%(B%-3:?9<%#H@:6>A:FB%5=77."E&HA;<795@=5?#BCFD*H5)):9):1%&1+A%690.$@6>%GEG&/<F58B(7>$4C%>2+.8<:&F$)0#=#)<<C*CG25&,?4%F5!88;>(9EG,%'(20/E:4=;791$'-0?G.*.!&96+#DH+$E@11&B*?,0=2#-6?)-=B2*)-$EC!C3;)<;#A($>*%57C32F341A.$-&%-><H;H2)=/78&0F*=+2813B'8++-@C4BD/>(4C-%5)+HEGF<2=A;#8>45:>=-4#D)94?98/G$'=#$1:7-,.#B@CA:*6*26A<(?/9+912FBB<94'BA0-H/#5/-;+2%F8"G!F/.-".@'($/6-D68&/FF<5==43(C78>9*>$,4A)F'A*G?6B+,1HA8H2,%8(>%8)AF&!7)@!G6F?2(/*2(*E/,69H;,;":G8*4<
@r5099
ACTANCTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCANGTAATCTGGAANCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGANACG
+
%%$*"+&&(*)*#'!%$++&$*#''+"###*)*!*$*$+#$*")*%$"#(!%#)&)&$'$'&(*+'($&)&$$##'#)#&!*!+(%"+*+%'(*#('!%*)(!$+"#"'#(#%&("'()!*)"$!+(!)(%$$*%)&*'&*%%
@r5100
CTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTC
+
4H,(#G*4=1D9!!;*2$7.;)"B'":C9=F6.D&#0@&*9";!@4.F-?*(8<+0E=>9=%6;CE&D,*<"'$H.#EE4"5/):6//6#E#:H!2'6-*A*.+?$6C).9-A;%4;9-&&A3/!A
@r5101
GATACCGGTGTGAGTCANCTGAAAGGGANTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGNTGGCTTCCCTGGGGTTCG
+
D!#:F1G;7>576&4E@:91'4F&,GD>.*@0+>*BH-$;64>(H?G#G%?/97AGB?@G5/B#F"<2=042$,F/.#H8=91:<5*51)+
@r5102
CTGACGCTCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCGGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATT
+
E'(9B+8D0?.H'5G/*1A!+8D1+:9F&3(H891A9H3AG;D;&!7<C8?>?3E#?%*84)4.,9,>B;1*#/A(=G9#E-0%5G1*+:'(>"GH-<&/3$BD7?G!GC1'
@r5103
CTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGG
+
*1!8&@::B#:)B85''4'9:30'%=?7G@0&9F@8,=7#8ABD1"0.*&
@r5104
TTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTNCATCAC
+
1:*+E29)6!(9<;C'&;H8',(;&#$)-(5=08=/4C#,0051+!%@3F.:<7+B:4*?
@r5105
CAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTNTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATANCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTT
+
>4A+GD,,9;'+AB-&-$"F)=%;G.7<@>.)1!7,!5=8++BHA/!H602$@H<G!@2C)A8--1,@05+A(H9<"(@(6ED@$%&A0#'500@,15"9#9D#3#;:.)3-%"0F*,.9-GA6&B+-*A9(!3*+3?7B1G>#D"*:4*(@+@?C-!!&6BEC4+D/
@r5106
AAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACANCCAA
+
8428CED7H$1;=;@@G@3-,B3@&>?(8F@D@2;5C<!?/=FE!)2)+.#,DD"#?"@D='
@r5107
TCGTCACGCATGNTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGG
+
D=7="@F3/%)GDAG%E)+H<6@4;>-=>@1=#9G2+G12:>0H&<@+87CC+"AGA=$0<72D!8),0((0'+@61%$
@r5108
TGTTTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCAC
+
0G%2/$F1#3@+>?0/2!#E5&)?4@8":&8>C0/;61.$
@r5109
CTNCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCGTCATCTGCTCCATCACGCTGTA
+
4@/HE(3;.),=:=G>,8?-,F>(6.ADE2''+<6!7*C>B3"81?%3%";45E*>7
@r5110
TCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGA
+
7"&5/5&4.D$6(?@*>#?&%27<2!>5;0-!@1(/&E'/-HC%',$'HEE;,-@8EC#G(9!*22C-3
@r5111
AGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCNTGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCG
+
3EC,?@>=B;:3G22C9AD$F;D8C#-"?#";93!+B4>(HC51'#+;.8H*A$5EGA$"16;:&#C'/:E28+!=037->&492"7.C0667+2
@r5112
TTNGNTCANCTNGTTNGATCACTATNGNNCGNCNGANAAAATTNCCCNGGNTCACTNNNANNNNANGNANTTNNNCACTTCCTNTNNCTTGCGNNANTNCAGANTAGNNNNNCCANCNCANTNGNTGN
+
"!!$"$"!"$"!""$"!$#$$#!#$"!!!!"""!!#"!##"$$"#""!!"!$!"""!#"$!""###$$#"#$$!#"$"$$$###$!$#!#"$$##$!#$!$#!$#"$!$"#"#!""""$$#!!!!##!
@r5113
TGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCG
+
".9)-F"(,-&-061C-0/$:)B.@C*C?6GG"C>*G7B1"=#)7G2FEGC)-5<2(?2(#F%/+2=>8
@r5114
AAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCNCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGC
+
?*5%629$C-D)=2=!F1<F6<=(*#8=+A(A5-$=:?<$A730#%0GE.%#30)#0B/G-;,H4?07#+#04"?>4;5=:;!,;F*#<;C932F'&5(!:1A56G23,>4)@,7@A$D:&2A,
@r5115
ACAACAAACCATGTCGCTGCCACTCGCGNAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAAC
+
*-74@C&'D0-13(2-+'2<%.&E$#E<H;78"-F2AH18F'"C-7<7,7CHB%#?<@.,/DE6@:C5F7%+!
@r5116
TCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAAGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCG
+
)+B7%)-B4->**C5);"/:#')6-(G*9%70C@216%$&'7G3<379-D!6?=76+6:=7&33>8B!-)&AH3E"<@9F:AH668/5*%<".'"#245#'&"088<0":+&)#,32;"&,)%60''/G1G"D:>!,/*D/43!B")=%!!78D6?D!BF*G':/843'0?*"HG!D?+4G<A$"GH"A*E4.2)2'%)$A>>G6!8=9E7=$02-21C2E;,;+?/5A9%?:E(4!(1A,-=$.<:.(0B:BA#@,<%<@;;D);)))#!@'9&A#*2.
@r5117
GAATAAAACANTTCACCGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAANTGGCAACCTGCGCCATNGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGC
+
)+)"#+!(!)'*#+"#%'&%&##&$'+(&!#+"(%("+''!)(%##('*!!")'$!)!(*+!(%#!$%#!$)$+'!'))#+)+)$'))#$')%)!*&%!""&!*&'&!%)*)%*
@r5118
TNNAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATNAAGCCAAGGCCAANATCTAAGTAACTAGATAAAGGAATCGATTTTCC
+
#)")+*&"&+*$("(&()'%)$$)''%&+)$"*+'"!!"%')!'!+'**$*+!+%"'*"+!*&&'+$!&&$#*&&("(+'!+)&&*&(&$$"!*()#!')+(+'&*$'&%)&*(!!$)#"$#+%'*&$'
@r5119
ACCAGCCGCTCACTGCCGTCGTCCGCTGTTACTGTCAGACGGAGCAGGANACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGT
+
G0+;=3'(7)D08(7-(#4>$/'-'CH-,'*!-0G$%<"$6)AC(E9);G0$=#&D88G<59>,,45.#:'?@)%37#>B?=6'9H?('@HH(H9@;$5&7"./@B0.A(>!%"(D6'10020D1G2C85D"5/8A*=9$(5'5(#9(77*0@!$
@r5120
GGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGTTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACTCATCTGTGTCTGANTNTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGT
+
2D-/=,8+3G6&0A+61+:#*#".4<GD%:C8C(/6*,5&<>'#"%.015&1;G!C&%9.8"7A";6(#9G14#$3GC0EE",$9-+.>63-"/8(H/&+)/C;>8%:1DD6!G7..BFH)3C.,D%G2H69C)&/+9"6HH)!%#&<?"*0A295-4D-8@105);&.!@$F6A!'&-GB15E!+$)E@;,(@+.?GB#$38<,<<)0A=7'99+C<:72B75H":?6
@r5121
NANCGGTGTGGCAGCCGANATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTG
+
"%"'(++)*)'#"***+$)%#%&)"+%+)+'&"*+"'#%($#+(!%))+#)'"%("$)&#)"#(%#$)*&$)"(""+&&)!$%$
@r5122
TACCGCAACCGCGACCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGC
+
5$@,(5)?.)4E>*C:?F=10E697%?E*"47A!>8)!$@/*4($*H%B90G(=?.(.8
@r5123
GCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCA
+
3:6.!G&G/00,@*1G@65D-H?"2$==/+$);0>%:&9((+3G5=1#EG/@9#FF72-G$F!,:@8-2)2@%
@r5124
GGCGCCACACCACCGAGCACCATACTGGCANCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAANTACAGCGCCATTAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTATCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGTTGTGTGGCCAGT
+
$+?H-=+149+A8:D*<D@;1,@87,G704HF"H<0/A+)E31.99$+9>G?>A9375":!@A.<?=87?'&=G%44%':2E,.@"5FB--09*3F86:4!D>!'1!32F*>.6&5G,!+<A-&)1G$8+66.=B>21?EH18H,G4($((F."%B?9?4>9G))'?"+"8$%B,,$3(&<G="F)=4(2)5&B$)DH;3A$+D:.<$<E06%"&:'B+"D$8703C":G08A7G<9:!1.E*A0"*&3<)"9=B4C!"833;+0E6D(&8;?!EDF!-9":(2E1'(8::D<>8-BC8",&5(**CC!G<C&-%,=8$&%BCG:5/&'C
@r5125
TACGAAGTCAGCCAGAACGNCAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGG
+
%16E,4!9D$%>/+7*D-"<CG!9,'C#&?"EA9C%87'A@78,C:9*+$"$88+71*7&/580F1GGA%
@r5126
CGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCA
+
E6))-DC2+25&@30%$)>0;D;>#'BF64F6FD0#1A#>D!5+=6$ED/4($&)9@@;2C2C666<=#14:451F.>D+*@8%6.84/*B#A'75!-7A*2B$$
@r5127
TACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTAC
+
'.*693H,-!#:%D:@":+;"-2+H<2D#G'-1.7D&8/(-448*#6'6D%&%B9A73A*>>1D=.6-96:)@E:H+=)4::>.F.9B9,606H%?902H+A5&5/@5&,<0-&5'D4
@r5128
GTTTTAGGGGATTTTCCNTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGT
+
"G%&,"B:%@8F')/E'7:@!A0'-0<G=-%39.&F9&*7+B(G%2/E@HA;C->,9$"D
@r5129
CAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCG
+
;?1&F//264:-"0)@*"/%BH;.4B/62/4#B=*5G<:!7&,5,#7B-':GB**<3%H<C2>BD,7BD-&.*66"7'7G+9?=*8'G8&H)94,;;4:2(AB-1037,8D<@&/E!$@BH0%?2!D($=?8AF%C+);'*FG2#F5:"G
@r5130
AACCAACAGGGGATTTGCTGCTTTCCATNGAGCCTGTTTCTCTGCGCGACGTNCG
+
;D9&F!9B83+>?.<?$?6+5!->59;E15/);,)F!0-&)#<71+)=)?%=96;
@r5131
AATCNGCAGCAGCAGAGNGATACCGAAGCGTCACGGCTGAAATAGACCGAAGAGGCGCAGAAGGCTTACGAAN
+
!%%!&)+#*((&+++"")&"#')#*$*(#)#&****("+)$)"&&)%!#++&&+++$(''))#*#*)$!(!$'
@r5132
TTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGGCGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGNCGCTGGCATTATCCGGTGANGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCNGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATT
+
1+8<!.59;58)*;C)1>:@"56--D9;"$>0;B.")0:363/.F%!,./>H->@;19&H*1.$3AA'5BG8GE1$+)162="3C<%*>!-F#;)?72;F-#8G)4FG;A-..6+D@*)+G+$%B97&@.0-&#D+0%5D4+*0/8<G/!H@"<A#6<<H3(;%F>@A-4"F"-9>$4,$.F5<@!&9)+3+6598.(7(,.H;,5)8%(3')F#9G+=02DFC!.C;*0$'-!3)->C;*(5'%
@r5133
AACCNNCCGCAGAAGACGCAGATGCCGNCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTNTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGNGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTC
+
''%&&%+($#((*$$#&"'*(+(%")'$'%#**)%(&"(""%&'"%+&$%(!+%*$*!#($!%()$&'+)&$#)&&+#%+*!!!+*$+*$"!*%+%!$*+*'(*'#+**!((&&('++'$$%($'"('*!#)&"*%!("!(&!"&)!"&%"(*"*!%&(*&(###))!)("%%#*(#%&"('!(+&+"#*++)&$*&$%"+#($!!!"(!!")+$+*%*&*+(#'#+')&+#$)%!""%(%*!#&($#("+!+*#)$))+("%(#($&+#!&(#+&%'"$*$"$*!%#&%#"
@r5134
GTGGTGAGTCGCTCATCATCGGGCTTCTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTC
+
0>)2;C<.?6944?96/7!(/?4.)30C#($GBH+%D9%%A)*?G<E(;:H&-9A),*:;83
@r5135
CCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTTCATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAA
+
-:=>%/3'.0"@,A>22("61'#4**@B587;A2.?.@21+/BEC4$E&A=%C,H;5808G0<#G&*'**$&?HG8%G*,F,3B!<G5E3!1#%A0"+G7&+%47$;C:+9=4@))=$8@*@F0;H,3C.'
@r5136
GTAAAAGATAACGCTTGNGAAAATGCTGANTTTCGCGTCGTCTTCACAGCGATGCCAG
+
69,H2;-1BE0BA$%<34:5A7:$!!D'A(8A>1:(8".H!((BB9#!.*50'6?7?6
@r5137
AAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTAACCCGCAAGCGCGTAAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTC
+
88&/>-@?A,??1%#$402/4%$78<8?',**!;+$$/<#@"G4/2%30?#AD))>=FB*%.EFG5;2A9*C)3FF:6,(<?A629+396>$1$-*&/4':%C.'99#!G,7F55:G/,=00F-;"8)+
@r5138
ANCTTCATCATCGAGATAGCTGTCGGCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGNCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGG
+
'()*)*%+)+#*+*&+)#!!'+()$*$"!*%#&%"&*!$$)"$*+)!((%#!##!$+*+"!!)%"%))"*)%++)*#"++%$#")"'+&'!&+*&!"&*)%!&#"*("$+"&'&')*"*%'"+$(**")"+&)$'"&'*'(%$$%*'+)%*$#$+!$#(($'&&#)(!*%*)"&!!
@r5139
CCCACACAAGTGGTTTANGGATGAACAGTNCTGGCTGGAGTCAGTATGGAACAG
+
78')8"5("46""E&+$:'*HF:09A=B?24,A66C1,%CA-EC3EB=.4%<G;
@r5140
AGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCNAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTCCCT
+
G?.<*+%"#EDDF9@2+/%C71.8GA"-7!?/#F'E-@C>69GB%*86=E5.F,83G0#7;.#>,4@-HBH,!3!03E'61;(<3-E+F94=9C90=):*!H<5<H5&!($61@(!G7G"*-.658,@&6C7'A2E3A3;
@r5141
ANNATGACAACGGCAGCACCGNCCGTGGTGCCAACCCACGCAACCAGCTTACGGCTGG
+
*&#&"#$*)"+(")"*+$&#&'&#+%%%%)$'%#$#'+&#"(*!$&)($"")!#(")*
@r5142
AATTCATGGAAAAGGTCTGCGTTAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGGAC
+
(8$B!.<9B?.%B:B!(HDC@H6-@2AE"@,,@&>/41*%*E9F!:7??;%?%37.HA=C7*5/)H!C##(?8592@1+D@AF%#H@..(G8$#<(;:6
@r5143
AGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGC
+
+!!#%('!+*!$!#++)!+''++%%(+"&$)"%!&+!"%)#'%
@r5144
NTGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTANCGCCGCCGTCGCATCATCANGCAGAACATGCGNGACGAAGAGCTGGC
+
!#%++)"%&%%&+$#*&*%"($(&##%*$+)"*()%+"++(("!'#+'&%*#+'&'!"%$##))+*"!&"!))%*"*%%&+*+"%+(("#&&'%+'$*""#)+'&$
@r5145
NATANTNGNCATCTGCTTTTCCGAGAACCAGAACTCAAACNGTACCACATAAACGGCANGATGCG
+
!%"(!!"(!+%"#!%!#*"%#+$+)'"#'')+&"$&%"'$&"&'!$!+)'&(*+$'%")*)"!'"
@r5146
TATCNACCCCNTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCT
+
"*)%!"'*&$!+)&#"$$$&*#)+($(("!((+!&$(%**($!%&(&+('!"!"(+
@r5147
GGGNGATGNTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATATGCAGGGCCAGCGCAGAAGCGAGTAGCATTTT
+
)$"'%))(!&+(#!)'))#*&**'$((''*'!$%(!)#!%"+&#!&$%*!"*"$"&#('*#%'&&'!)*!!*'%%((*"&&!*)&)$!&)++"#%")+'#&#!!%!"#%
@r5148
CGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACCGGTGAGCCGTGTAGTTGAAGGTTTTTATGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTAT
+
=627,F%(@,H&(6@"BE591G4D&A%#G%.C"/*76HG27:-<*4F:9/+#%>;(#)!*G4;=,*!<*B&,(<-&:8BBA#H1:C!H/F!)F5'+'&.>(CAG#D*9)#!E>')&;=0;&8$+(2&0$7GC#B!G"3=02C(#?#4#+/:<3H!/=2&+:@*B*#?(0.F?*&?:#D;($#G8.>A9-?.3"0"*#980<'-"G#*
@r5149
TNNGNTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATA
+
')('*'$#'#+(+#%%%!)'&#*'($!$%'%'$+&)*#)&!!&%!*!+)("'!%%)&')$*##&*%)*+'$)"$&'$'&($%"+*"!!)&+%'"$"'(#+&+%'*)"&#$#)%&!(#*)"+
@r5150
CTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTCGCATACAAATAAACNTTCCAATGGGTGACGATGTG
+
-*EA9<(D>8#&A4=GA5C0(':.;E'@5+D&'3:#0G8)(:9?=H-)@&=?0DF;>&#329#90DBC6,"FA9C8?
@r5151
ATTNATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGANTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTC
+
+%),9H')91<F7>94'=CF78;'9,4B;>E1%065CE5%0(0(+3G=&;B,G1)>=(->"9GH$E"4?9-43,%8#E@9E$E31E=*$"#/B5%,,F,6HE-7E@#D,#C8!@;C'*5>A)(@?>&5H+&@*2)54!>7EH&(,G)>**A+4G
@r5152
TCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAANTCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAAC
+
CB@*24(@.)&=;E@20&("G"&$G-#*)2G1<$;?&1;:6+$=FD1?)B(&>C!D#*<6AGB'&6(H7+1F.%<>79$41/@%'@82&C90'
@r5153
NTTGGTNNNTTCGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTT
+
&"&#$'&($&#%+)(*"#!$"+*(&%%('+$(#+%#*$*'%+&!!)''%&'"!)%#$$)&'($$))%%'")%%&())&$#())+)*!*+""!!
@r5154
TTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTG
+
7?0&,BD,8'0*);#?!/(?A+*/8(AE<E2?H=@.-49=/0G$306*:3$.$;(<>609,*<G7E4
@r5155
GNGCGATGCTGATTGCCGTTCCGGCAAACGCGGNCCGTTTTTTCGTC
+
!"+*"(')&*($'+&+"()&)'$"')##&#$%'#+)!!()"#*'%(+
@r5156
TGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGNATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGA
+
'E.G.-$5!5G&04+3?#4+8(:55);+!:.:&'=#55%(76E273&"=3&.3/H<D'96/@(7&B"?$4;H01H77.C=$?HAA9B.B,36*7?
@r5157
ATNNACCNNNAANNAGNANNGNGNNGTCANCNTTNGCANTGANNCNTNCANTNGANANTNTGANNNNNNNNATGNTGNNNNNTNNTANACCTNNANAGNNNTANNTGGGNNNGACAGNNGNTNNNATNNTGGNGNNATCTNNTNCTNANCNNACNTNNNNANGNCNANANGNGNAAAGNNCATANACACCNCNNGNGNAGAGNCTTNGNNANNGNAAAAATNCTNTCTTNNGNNNNNAGNNGNGANGNCAAAGNGANCNNANNANGNTNCCGANANNNNNTNNGNNNGTGTGGNTNGNNNGGCNNNNC
+
"!""#$#!#!#"#$#$!"!##!"!!$$$#$$"#!!#"#"#$!#"$!$!$$"$$$!#"#!!""$#!!!#"#!!#"##$!#$#####"#"$"#$!!"#!$"#"#"!!"""$#"!"""!$$#$!"$"#$!!"!"!"#!"#!$""$"!!"#"#""#$#$""!!$#$$!!!"#"$$!#$"$!"!"$!#""$#""$##""#$#""$#$"#$$"#!"!!!#!$$$##"##!$!#""##"!!""$"$$"#!$"!#!#"#$#"""!#!!$$#!!!"#""$###""#"!""$!"$!!""""$$"!!#!#!!#$#$#""
@r5158
CCNTGCGGTTGATATTGCCAAAACAGAGTTNTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAANGCGTCGG
+
0?)>':<9@29+;!)/*%'7DE/?9&:<=D53)8CA1B+1A=D@9E0&B7>)D&HC'H'<>D;E!-<E.BD?><A+7A
@r5159
TAGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAG
+
&#=4+%DH</)!*;'8(B#CE7CA,';C'!(H9A@B(@81!=6>6B$9)&3F!
@r5160
AAAGCNCCGTGATAACACGCNCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTNAACAGGAAGGCTCTCCGACGT
+
*+D,=@+2-BH7)72G.E#=*;5C'BH2#.DG4?68?B@?B/4">G&C<85)'>"/7#<"<5>""9*8BD2?=$+8!"8"7>/$*%+!F949"E#B<>'>D/067.EC""!83<A=(>+1+!+>#F#;?$A"!:<%<%F&!/-2$,(#0A@$)%;*C;%"@5D;0A0&0>
@r5161
TNCNNTGTNTNGTCTCCATGCAGACATCACGAAGGTGTTTATGTANATGNAGGTATAGATATAGAGTCGGCATACAAATATTCCATGA
+
"(&$&'$'#)$&%**$+)($!+'%#)#$(%$*&''&*#**"$+(((*&'$&'!!%$&()#!%+!!"##"%$%&(#$#!$%%#)$$+*'
@r5162
GGCATCGTGGCATCTCGTTGAAGACCATCGGNGTAAAACCGNCTATGCCGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTAT
+
A=#%B0282AG//8939H+@.=5=)9G37=46/9!#DA+7C!/D?7>F?0#H+-D!1-+1$D,.)#1G3",2-!",#.%FD<4,0A(094)2%1:;38,-#G.HA>DA+&(9+;0D
@r5163
AAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGNCAAA
+
*>/&,*HH!=GA;51F!(H()3G+5>?64;86H1%13G!/E&A8"&BD;+A#@(+5'&$4..",0)93#4?B
@r5164
TCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAAC
+
=#+03911';+=%G"*2A:/HC>%/H+!-0?FB57',E62%(126%%%1H5=)(',>F<1,39'A+98(<$9$4&
@r5165
GATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATT
+
5D%C/$1H5E'F$5F8..+/,H"GB/-;)AC%A8!8")062!8<=$:CFB<'A#.G(4!#(9A4C,C85180C07>B)AAG-&&43:?)7/&<+4-%:HG$.?-)'G3-(76==+('4==9AE4-
@r5166
GGATGATGCGTGGCACAAATTACGGCTCGGCGTCATGACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCNCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACC
+
22<'E+>!=E<",%H,0/0:<2F,&A=E-)/)"/"!'-%$,:2745()D#/!2=882"(-9<HE&H-0="-5/*H.C<7?.?9*;"@+-.!?-%0"/)1+GD93EF&1+,4>&@D)G)3-.;!$*E74*4*7@0))3@<?>D
@r5167
NCACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCATGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCC
+
!F8D.H."2&HB%*531FA#=1.1:70.1$3C%156::F&!,>6#(0+=/>H/*1$527C;/>@E,:=7C((A8)H/$?F<F:$!29.'.F%;E4H(/%1,19<AA1@CA?@53C+-C"HC@:91&3,(7:>$%+1:
@r5168
CGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATA
+
"#A"(;%8C0$H+43!7=G#D*,(6,>=.)'@F),E1&@,,/@.4B
@r5169
AGCTTTGCCNCACCACGGTATTTCCCCGANACNTTGTGTGCAAATTGCATCAGNTAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCT
+
+!5.1&1GE(E?H&=E'"-0A<F7C*D>*HG<<B2<FG'&#,H(#,)CH%=5-26<0=?AA2<DCG;!D87BH9"H"9@@F!5'CHC9>#/:"/!+H
@r5170
AGCCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAAT
+
:3;@1;6"C,7';<=!F/.!>C(?/C,593+&1BH>:F:4$+)(,3/C>F!F<A<2.;)@A6E#H'363?=>0A$68FEF<EF@:%
@r5171
CCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAA
+
89+1)F*2B00"CD*@G<,)3<D677#.8D2.*)&.5-5+B!H%,)+6A4+(6".D#6)?6;#A5<#G;3@:8C#
@r5172
NCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGC
+
'B%F3'AH+78C@5&"+$7DH:E93'4!>4$(<)?2*<1C'/'H%)6!.&+
@r5173
CATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCNTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTG
+
!(3!FB/-4>.?1=1?5=1GE4C/,<C+,E++D3-()A""!G9(?&,:%@D??FH@'9:7)(HAHF8F&'/$4?)@8<-35,E4;=3,@F@FF-9C?&3!B%?A.D>C5BD/@
@r5174
ACGCTCCTGNCCGGCAAAGTTACCTCTGCCGAAGTTGAGT
+
@C5G'&+<-$"H(4CE,%//0=+)D(5)!$31+9<!(4=8
@r5175
TGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATNAGCCAGGTAACACAGTGTTATGAC
+
B=@9-')65+)A8.*51F%CD+H/F194;D$FH6><6'C9:1!",&:%<(+*=2B7D@3C(#H
@r5176
NTCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTACGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCGGGAATCTGCGCAAGGATTATTATNTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGAGGATCGTGAAAAGGCCNGTCTTGCTCTTGAAGCCGCCCGAAAGAAGGCTGAGCANCAGACTCAACAGGACAAAAAT
+
$?*351"9E1=,;(8E!09#B()7;/@75-/?-E8=<%&4GD6*<D9E;D3E>)80HB8!.G/:5<=/>@!-&'@F*,,D.64$>@5@9%;@39+0;A?#H'9*A(?>@7-!;C!*/>4848%>:39(D,@06E>$:?DC.68(;C3(,,:11E&&:+17E%@/9:9*+HB$G2<!BBH=<"6H3'@6;FH>/-F680=6=')E8<*=4F4D4HDB)="5)*:6E):"B*?E
@r5177
CAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAAC
+
;<&4=(,2=.!HB>0#>*6<*;H4@<?A$.,8H95%---8F@0@%,E,++4!
@r5178
TGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAG
+
/(H/G=6)/==%=:7B79*H":*?%,D?GA,B&@/F"H#4>@#>/%2-3&)*)AG:/A#HGC<>A6A22&=.,E+2)73BC&(&6&A.F<#5&23F?@1'50371=;'BE26<,
@r5179
GACNNTTCNTNNTACNGTNTNCGNATGGATGNTNTACANNCAGGNNTATCGNAATNCAGANNNNCGNATNNNNNGNGNCGNNTCNCNNNNNNCGNTA
+
####$$!#"##$##$"!#!"!#$"##!##""##!!"!"$#!!##"#!!###!"!!##$###"#$!#!!"!#!"!$#$"!""!$$##$$#"!!"#!"$
@r5180
ANNGGTNNACATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCNTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCNGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACANGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACANTTCATGGATTAATGAAAGATGGCAGACATNATTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCG
+
&#"#(&"$!&)+*'%#'"$&"))$$&)'*+"+*')"#(+$*(""())"#*()'!)%"$(+%*"'(%$!%($(($*)()#%!!#"&+($%(#$%%%$#)**'*(!&!')(())&&%*#%+&!')+&#!($*"%##*$&(!*#(+#+$+#'#*&*$$#(#"!*'+)%)#$&&#&"*$(((+%'"+"$!"%++#"+%$$$'$)*'*&$#%&##$(#'()&&()+"$*+(")"%*"")$))&"#!**'!('&)%&$")#'!%+*$%*!!'&#"$#)*(%'*'+$!+*$+!$&&")*'!&$&%+!+"##&*"&('*(())$')%!$'%'#(!'&*+)#$())&&(%!&!&+$!'&&*&#%)*)+#+!#%)'%$(&!(!'$!&)%)+$%'&($''*('('")$*))+)(&%)"'*"**#"%!&%&**&*'!("+(&!%)'%$%#)$!&$"')"($*)
@r5181
GTNTCAGCATCCCTTTCGGCATNCCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGC
+
"'!&<E?:;#(+4(>)0H@!">#*A+F<3C-'7/?D43(C),2=.4)H12G:!8<#G)B;;58&G+<$<C89+(H);:";.E.,0$6(?G,?/$6.B8<>2!767$!$=;><&=@F8(&<.HD47?C.8/.
@r5182
CANNNNGNGNACNCCNCNNGNGNCNCGTTANTCATCNGTNCNGGCGTNNNTTTTATTNANNNANNCGNCACNTATNTCNNAGNANNNTTGNATANNNCCTNNNTTGCNNGTGGNCTATGNANNNTNNGCAANNATCTGNNACTNATATTCANTTTNNTGNNCGCGGANTANGNNNNNTNNTNGCTNNATTCNNTGTCTGNCGAAAAGNNACNNNCNNNNGTAANGNGNCNNCNNNNTNGNTGGNAGGNACCNCNNANANNGCNNTGNGAAATGCTCAGNTNTNNTNTNCTNAANNTGCNTNAAGNNCTGCANCATNNTTTGNTTNNNNTCGATGCNAAGACCCNNGGTGNTGNNGNNNACANTGTGNNANNNTACNTCNTNATNAT
+
"!#!#!"!!$#$$$#"""#$!#$$!!#"##!#$"##$"#"#!#$$"$!"!!##"$#""#!"!#!"!$####!#$"#"#$##$!$##!!##!$"$##""##"$!"$!!#!$#"#"$$#"$##"!!$!!##""!!$$$#$$"#$#$$""#!#$$$$$#!$""##!"$$$#$"#"#!$"!$#"#$"$#!!#$!!##$!#$!#!#$$$$#$!!#!$#!"!""!$"!!""!!""$#$"!"!!$###$#!!"$$$$$"#"$!"##!"""$#$$#$"""!#"##$"$"$#!$!"##$""$#"#""!$!$!$$$#$$$""$$$##$!###$$!""#""!$$!$##"$"#$!##""##$"#$!#"$!#!!$$$"#""$"!$"!$#$!$!##!!$$
@r5183
GTTGAGTTGCCCTGAGACCAGGCATACGCCAGCGCACCGG
+
?90DCC0E5CC,.%9=8;@B"$;CEA!57F*3E432FF#'
@r5184
CAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACGACTCACTAAACANAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCG
+
46C!C4"7%%*%?35)>&67%:)9,D-3"?5%@D2A?$>*!.>5?,E#@,CG)5)'0@F<"8B+F(.3*/<6%0$25E"-C?70$A1CHFF<8B%:$+&A&,9*>.D<#/%-+?@:!F<E5>,@FE@/$>E46&98/<@<45':5E<;/@>.051235),#D,B:8:;6F0!3<G>,2762A90G=
@r5185
AAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGNGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGC
+
C"E*@A.>G'&'.9.H9*#!5A'F<C9,979?(::;).>?$2+3;8D9?B,,@9FG&"C$C1C*B"(%?<)H,')5:.!!#2F.A9%A@7?H*$8=HB.(;C6!D:&.EB#7#D99!-.@EAD*@G)G2B63/3@#=>B?@)?/;1CF0%3.;*&A;9$H3'
@r5186
GCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTG
+
8.;-C3('7:+A@.;))@'33;.,""@1A*)>1FG68$*H&,?1CC*F10!<%,*#+"8?6%#(%;,BA4*D71=B:>@
@r5187
TCTGCGAAAACTGCAAATAGCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGANTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCAC
+
86HA"2G8!3B<"DDE':*"+4.4561**.8=D=0"(H/+:#92:41>C9;)(;*2F&<3'A<>==54'?8)A<5A7-?)?)*(8("7<=>=-GA>&!A=:FB41H7?B>"7HA/0-6!/;4D5*H=H)%7)37?+6;6@15=46G!0G2#;)+"A*'E)1B6.6('FF6G=B5##.CAFD9"A.@/;796DD0@6#+<,7B<!F5;7G:>B4+C@3<@F@A72+<)FD4?A06+3&?)H,.?"!"3&FB6.#H42"37'HB4+9&:/DC86(B(:=@<B7#&<BF5%==$;1AF
@r5188
CATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCNAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCA
+
>,.'#7+-C?B*7BCD$6E=6$"F';/B'6.BF1FCC839E<93F#:)%3&-&6#<+&13#57?DFA<#**0-"B8/7G.;<,;"!;'-@2C:H>D//13G",3+36HG2'=11'?18#-(EA-8@,B):5->FA+E+(!$D0C29B"8(;7&#>+5;6DA"G*7C4'FD0%0"9(E=**?CD0)07>&C9G+%,?(*:0<?!G6":H?+@7<G(",>/:841+.A:1;3B@01.@',E")
@r5189
TNCNCGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGNGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTCAGCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGNTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACANAGCCATTCCCGGCAAGGTTAGGCACAAAATCCTNCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCATCCTGTT
+
)$)'*)*+&*"!&""*)*!'!$)+#+!(!&*%(((*&&*+''&+'!!)(&&"$#$&'"('!'$#)!%"**"##*((*+('#%'*)(%+*$%$(&*(""")''$("&)"'"*+*'%#!'("&&'*%&+"#+*&#*%*((#'))+$(#($!#'"+*+()&'$%'**!"((&"&%&"#'#)$)$&+("%*!$"')%!&""#*$+#$!*&!#"&+$!%#("%#(&)(*&"&**%&&(&&"%"$)%"&#&$$$)!$)#&+$$(('*')++""#'"%)"$#'"*&*&$''+%(+'&'*"!"')#+)(&$&'&+($)+%(**#)$+'()$%*(++"#%$$%')"'$(#&'!"&)#)&"'('+$'+$%"('"##!+!!"$%!+%*$+%&+)(#&'**%
@r5190
GTNTTCACCACATCAATGGGGTAACGGTNTTTCCCAGCCACACGCTGCATGNCATG
+
%(0A4&5!B5E0CH9%=/9*C)BA;?%G;:1=52&F%G5D&,1"6D2G+BC!*#&%
@r5191
NANANCGNAGATNCNGCCCATCAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTNGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGNTGTCTGGTATGTNTGAGTTTGTGGTGAATAATGCCCCTGANCAGACAGAGGAC
+
('$%!"*"(&))!#!($'(&*!+&)))"+!++)%+')'$'#)&"'*)'!+)))#*$+$&*&+%"+(%$$'+"+&"&!&$$%(*(&&!#$)&$)"&(&#(#!*&))$$*"+)**'')+"'"*"#*)#$+++)*&')((!*($+($&!+*"++&!!"*+'#!$&'
@r5192
CGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTC
+
*#:*B-?,->G73?*.A4C0>H->7'@,91"%#G'<%7DHD2$)7*$
@r5193
GGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCTCNGCGGGCCC
+
9/*$@1."2B1E0=<50+-=5.#5>%.FC@%34.!7E:2,42'4HC34A)$+8GF*60*6+9!?/7;:D+',&0'(>"59&H"1$0>,?(AD/A+ED0:7$D4'601
@r5194
AAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAANCTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAA
+
3'-H72,@F;$F*269D=GD#G71;+!!F(25HFE3;D1F4,#F(6*<>-?(F1&0032'F!%.723,H,?,2++3..#/(+$).<#0=8&(?.>'C;5*=5',,90%'$F<2*-6(E!:6*(>@&:#F8D.!GF@:D+C0;-19$3%6>H$HH$.6)>C!3=&C(48%A*
@r5195
GGATCGCCTCACCACGGTTAATTCNCGCAGTCATATGGACAAGCTCATCTNCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGNATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCNGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGANGCTTCTTCCCGGCACCATGCAACAA
+
G&B*%*'5C&>.(H=<D==*9+2A#-,8A2!6%./=H26C-9=(5>G1B%C?("80012D441FB#B@D=9?;F%&;#,D"A?C(H,$21*'#56;GE>;C<+(:.A%C;BH7,%'-GA.&&B',>C=;<;:@D9<F/7=$D"H4$'4A2=6F/2%71,(".(%#/.-,)$G=9CE7@?;?:E64E65%:92**230*1#399?=2$(9;)3;%DB@'(8?&+.AH"G=1F<&*"@C!$&."9;?18:/AF4((C$?D5101,(%B
@r5196
CTATNCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTCAGCGN
+
"%&""+'*#$#&#$('%)"$&%$+)*!)'&'"&*)!"%+"##'+&+$#%!$&""$)!)&''%+%%#!%"(&+!'"
@r5197
NTTGCGGTAGGCATCCCACCAACGGGAAAGATGCTGGTAGCGTCCGGCACCTGTTGATNTGAGTTTTGGGTTTAGCNTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTANATAGCTCTCNGCCTAC
+
&)&+!&!+'"$#")+")'$+'""*$"##%!+'#%*"(&&#&!)"(%('#(&&))&'(*'+'"#)%*#%#$+#)''&'#'!!+'++**&&'(*++&'"$"')%#&'&*'#*'#)'$'((('""((%!"%(
@r5198
TAGAAGTGAGTATGAGTACCCTGTTTTTGCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAATAAGCCAGTGATTCTGCA
+
;CG)3<4E9.,!?+2)5!37?%!<$2)=G;5,:;#HGD526-@;E?"C=G%51-B>#+(&(9#)E=A=00E3?52C6H/,G=@B-8;117751*-4B*6!BB4?&)"H)*+06/D>.C,1H5<.$*!@/:
@r5199
GTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTNCAT
+
E./,**(B<"G(+9H&,9:-'**=D)=FA;A8>9G*(G1)8>
@r5200
NGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCC
+
'>:F,A65A0G39(4F4D-A#$9B6G7#25<>@0AAEB.92-7D;G,?%GF,73:.
@r5201
TACCCTTGCGGNCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTNCCCGTTC
+
"D;3(%7=*G1#D>;@$B.(E1--1;"B%F*1';*C3)+1<;!AA<F3:?4?7*,&;3@
@r5202
GCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTG
+
.0;1D4<9*"C?$A4GH=HH.$F%9%)EG,&-);8>&(@F)?)2G6,C:/;$8H
@r5203
CACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTG
+
$'+#(($(%$##"#("%"""(&!(!(!"%+"$*"#&&&$'%*+&%*+)("
@r5204
TACGCTATNCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGNCA
+
(%#($$"!&*)&+&)*&&%%$++##')##'%+$(#)"#"((#&$((&#"$)$!&#"#!"('*!+&$#$!(($+%'*+("!*(%"*$&$%)##!+
@r5205
CNCNTTTNGGAAAAGAGTTATGTATCAGTCCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGTCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGNCGTA
+
&$"###*!+%(#*+"'*#'!!'%$%&(+$)!&&*)!%!!)&(%$!%+'$)+!#)**'!"'++%)(!()!*'%)("!!%(%$!&)$!$'"$&%*!*$%(()!)(*!%&+&"%&!*+"*$%"'(!""!'"&"'#$%!$&!(&#!!'+(*!*)!+!$'(!$&%('!*+&')"*+%))*&*%!*(!'+'*))&!%%!)))%$"&"&(&&*#)%$$""%$)'***")%(%&'#%$#!+"#!#'""*$&*%&"+%!&)**#$$&%&$(")+%
@r5206
NACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAA
+
!*)7$'E+D+59%A%$$%>";3FD.(+=#B<3$76"D.+.-%"E9"8-)*##9AF"-DD%C/4C$%&$+2$+,3;=E"9:1('<#,3?
@r5207
CCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTC
+
7$,))5>%EGGG;AEC78A:D<3DD;0)/.4.15$H';1,+(%#$.9/H/:C%#.=%@'.294!
@r5208
CAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCG
+
7BA,4"(1C@';E1>49GAF1.'=:B,:(,@$(9)474&-7,2H&F'B>+4;+!0BA1/(B/5F829&6*30'&"A*$2&@B5"D=C<%+7BHE93=G?=A>&EGD@1A4BD94EF0HC>-C,/1%+3:5-+@?"B!.9(:',':6!(GD*)'>;-D%$.*!3+G9(G-0@
@r5209
AACCNTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAANATCG
+
#(%!")+&+#"%(!%!"(!#'))&)%)"("#$($*+%("(+!!(&!!"$$%%"+*+)+&%$$##(&*#"%()#$)(#)%*%&#
@r5210
CACAGGCCGTAGCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCNTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATG
+
C1(/*+AA#<?C6<-6;;8,DD4%@>/C?E'8E/D88(.>2D0,;<&&?AC36?@FH7H=8>1(<+=@C3:&#A%B=50%E2.$?H<*C*!=,D!@/3E.>&/>3%'5H"(-(:D(F%H-59<01@,C7-?;
@r5211
GGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTNAGTACGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAG
+
D8"=#G;39>F,:73#*;$AD?!;F92F761GF.H*1$&19&'97';<8'"8G+A?/?$9";5''C3D7+?G/%G<?)2?)80E01A:C"5%:3(?'&"8=%4@""#.-%'7<%="%@95FCB,#<*AA6(!&2.@*G-G0CE@?(<?B>:'<C8:F6>)B%@86&.D3B*CG50@>F5:>ED9F<).EG4,-:#>09<0FF#HB74.;((-@@A!4'$D-E%
@r5212
TGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAATACGCTGCAATCCCTCCTCATCTTTGCAG
+
*//1+-BB(AHB;!300>=CF-4?E@;)@&.,A&$84C8>$<B">4(ABA>#/(=B3AC72><GF&AHB)G9B/0"4B4'!445*
@r5213
GGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAAT
+
+H?AG:;C@F#?23/3%%.66'(?.:253&,E:?+F;G(C</8@#:0AGF;$7
@r5214
AAACGAACGCATCATCAAGTGCCGCTCGTGCAGCTTCCTCGGCAACGGCGGCAG
+
2F7#=149<3?@70H5686E99.+4?74&D8FA>E+-!.B?"5.D#+<%</(+0
@r5215
TTNCTTGAANNGAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAG
+
%'#&*%''&%#!'$"*)$'(+"#(++%!!!)#*#')##*$)*!')#!+'$$'+(#'($*$*")!$"&&+#&#+(*&&*)*%
@r5216
GGTTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCG
+
"$)*+*(!*+'($)*&)(+%#&+)&**+!&$(%&!%&&$$+*
@r5217
ATTGGTTAGCAAGTTACTACCGGATTTTGTAAAANCAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTANATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGNACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCANTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTNTAG
+
<(-@33!%;,"7=/+E.DD9/-0242-+604E>!?#7B*<"E=*74G@!+D@(C=)C="G9066"6-=@F)0!==0'*'6"!9*#A@F$.=+FG(@>1H85D;2)14A)0':)(5(!B.7$?(2-+A%C%D((%>E!/3#C*2D;00*6>.5:(5;%.&<,5'-)!E1B'/=/2:HH,EFE!?<H>?,"G04.C7)90.H0)3&)4-4<?.?F@<8B,4H9/8%DED$+*&(
@r5218
GGTGACTCACTGAACCTGCAGACGNCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCT
+
F'HH36)"E449.5%9&BD6&@3>(C.&84,!267?+,07&0D'%F1+:;H:A//3H==6<$>G,B7*A,*H1#F1232D'HB-
@r5219
GATCATATACATGGTTCTCTCCAGAGGTTCATTACTNAACACTCGTCCGAGAATAACGNGTGGATCCATTTCCATACTCATCA
+
D8B3?#4080'(%+"&?096,'/":+7,;"3$B7%!;G//*E?$D%."5(#6CBB)9H7,)G2=-HH:0;D?:7.5%6H%?)<
@r5220
CGGCGCGTGCTGAATCAGTTGCNTCAGTCACAAGNGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCA
+
F=)<:-0*=A3,8>GG?2&F0?''F?@2CGE8-(7$;"$>;*ED$!>A;B)+B06-"<7/)-<G>)C;)$GA44235!;!F+.1C8=@#?A;;;B0!B8CE",@524/+G&G:!,1B-7$-(-DA1%93=2(&(,
@r5221
ATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATANAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCT
+
G2&=B&G:@@>/',H2,((0$'2>:%GC;2%;?*6;4D01">-!=<:"5))/73G(%$%&+3.-%?+!758.!0C<3@7A@6E&9@C)/=@<1A62<;(>!#6(;(:4C24!)@,">CH<??"F7:#C-/2*G=GC-&*B84!&EH,%$H466?.3,,EAG:7-3"'3F$$.ACC%E*<@%8+9%2<B('?B6$CCGA,*#$E'C?HC)59E-=$"&:8:.AA90;>)652686=234/;:5&#>1E9"1F/."%38@(CG4,96<9)
@r5222
ACCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGNACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGNAG
+
!F%7D,&!B$'!C1=%7();CB&4'9).,0"F1-?G4<D3'DFC1#9'6,/G@B0%:+&%E*@=*<.(.@4!D23+:F!972!G#E'E>$H.*%!#">H16:+H6$@H1*C.80
@r5223
GGAAGTCAACAAAAAGCAGCTGGCTGACANTTTCGGTGNGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGC
+
?D(A.?,,731F!B'2EC#18G;?F?8?%F,<H>=B(+@*1A7H#:2-$.FA&49'9D.3G'$B9,%%"!8B<,&))3"46-1=1,%5*
@r5224
NNGTCTTCACGANGATCGACTCAATGCTCTTGCCTGTTGTGTAGATATAAAAAATCCCGAAACCGTTATGCNGGCTCTANCTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACNATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACNACCACAA
+
!!%+"#&$!$%"%(&*"#$*!(!)+!)!!(++!#*!"$$#+$%#%%+!&'$"!(*((+*#%%"("%(%%!##'$()$"&$))$#''!(%*!'#$$&!%*)%(#%(!(#'""#%(&)&")#%(&$')+'(&%))%%$&'+'$+""!'&#+'*)&+'*%*)#*"%+#"%&#*+&&"(*)!(*%%$)#$'')'"%#"'*!(*###'$*&"&&"'%$('%&%')
@r5225
AGAAAGAGTGCGGAANNTGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAAGCCCAAACCTTACCCAACCCA
+
==",5@D$(ED-:,7&0>"G46F5+-E<,+,H'8+G6G"/(:#9<+">$31<(6G7;H7C$';$9*$D9.-$8'*<A.#E2#!#"25)%A4DC+?F$<)F>$
@r5226
GCAACCCGCCAGATGTTTGCGCANAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGA
+
906$;3*(&>E":.3%+2?69!/%:?E6167E/=51<A!9??C7'(D">7D=)4D&BD1&"#7)/?56
@r5227
GCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATNAATTCCTCC
+
D@*0'73:+%=8F"6&@1"8H)'B4(83*2C=*=8$3F/$;H2&0F%+>.>?E=1D72A$F1$"->7A0%E,=/466@$;A?)@-H6<5&H6#%94#>?!GG3A7/*&%"12<">!GD-5;E:=*:1-%">0F%2H>!6'
@r5228
GNNGNCNGTTCATTCAGCGTATTCAGTGCGTCAGNTGACGCGTCAC
+
$##$$+"*"##$&"$!&&#()+$")#$('##("&'$'#'&'$'*#&
@r5229
TGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAA
+
6CG<%?+)FF2H50E#'-69,9D2A<AE;0=)((2H9$5B/#9+BA'F%!/290>
@r5230
AATGCGCGTNGGGTNACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACG
+
#1'/%+F<*C$,693.G+H)"*>B#$/*#5&7*G6;6A(""9&AE5"29C
@r5231
TGAGGTCAGCGCAGTCANATGCCCCCGCCACCATCCCGCCGGGC
+
6AC'D11G=@,;)A.3+*.-+&<D:,0&B@<C8(BH..+5</#E
@r5232
GATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACANCCTGTATCCANGAAAACGTATGCACGTCTTTACCTGCCCGT
+
BBBF$;+)8,4#4$AF3;.D%D%8+*4#C#42'7*%2C$6*H&B('?7':?$=)1.92*'F&F#>/GG,8"<95.*G8;<+@4;CHHE1%G2(HFF*=1<:#(11?E..)-25;2:8B=&)(%D,0
@r5233
GNCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCACTGACCCAGGCTGAGAAATTCCCGGACCCTTTTNGCTCCAGAGCGATGTTAATTTGTTCAATCATTTGGN
+
!!G>2>9E@:G',,5758A5-69C9>$/'&CA$933-H5".$";#D/13&A*88H<2&5$"B()";'B$>6=%(3A4%)7)5$5H0$';**0;B6D'.<@'#B%CD->?3EDD2D?@F8F'%-D)4C-%-2
@r5234
ATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGATCGCCCC
+
F>D?-"87;E8?@/%<>'G6&2).!3A<!9#??%HF0850D>F=@.?G&?
@r5235
NCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCG
+
"#*+#(")))$+%%*&*"*%)(#%*+(%$$#)"')!$+$+&)!$*!%'+
@r5236
TCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCAAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCG
+
5;>#!9%2!>?1.1F).D'8*3@.(3=,&-*(>A3&C*6+#3*6B;A7;6'%>#+&'#(B"3"F%HA++*5;)!)8-?C'7A(%*4*3/-(4*(46-)0).GC06G&D4(:?)D?(>(C,A.?>*D-@=#='83!,HEFD-2
@r5237
ATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTG
+
9:+4F:4;5*!<*",)"H&8!%;>$G#9(.,1>;@44%*FD05
@r5238
CTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCC
+
9B!=++C&2"8+E5?33;#CB!<49D.(>"->#3?-E0)%9GE42&/">=#BH>&(HD
@r5239
GGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGA
+
-8F2<1-5;21@6@8&'?@A<F.:);)%A7(F9E:G$$,G6*D8!)'/6%04)10*$9<697#)?<--&.895+6.4',E$5H(G=+=&0FHEH.<A+=?DD>?H&$&
@r5240
TNNTGGGNCGANCNTTGNAGNCTGCNCCNNNANCGGNNGTNNNTNNNATGTCGCGCCNGCCACTNGANNTAGTNNAGNNNNGNGGNNCCNNAGTAGGNTNTGNCNNCANANTATNNNGNNAAATNTNNGTNTGGNTGTNTNATGACTNNCNNNANG
+
$$!#"#"!#$#$"$""!""#!!"##!!"$$!$!$!!#!"$$##$#!#"###$$##!#!$$""$"!$$"!#"!"!!!#"#$"#"!"!"!$$!""$#$#"$$"#!"!!#$!#!#!"!!"$!#!$!"!##!#$#!!!$#!""$$"!#$#$!$$#$"$"$
@r5241
GCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTC
+
C2"=F7&&$3A+B/F4-9%.#*(4'A.BAA7EG?5A'!;<HC7HA:#.C;=HH%=#(0;(6*-;'&@&H'5)E*$6175:19
@r5242
ACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTANAACCATCGCTTAATTTGTCACCGACATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAA
+
.7?HG:5.?3H0$HD&7@D:FF<!#%*0H-7$:(./>&8(#B6-@*#"5?8B-F'!!8G$22;8+;028C460%A04/G"DB4#EA&2F'5/8'102C-#,%68F)*HA19,99
@r5243
GAATNCCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGA
+
B670)FB0H+:FG.@G9'0-!C!>E<654CG)9C-C>B)9<,#<96!;7?!
@r5244
TTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTT
+
9?4,3HB:B,41=%@45"0A;22--#4B&>B*,B><G5('?385FD1=%3/):!0.42+E
@r5245
TTTTGTTNNNNGGAAATGANCCATTTACTCCTCCTAAAGAACAACNTGNCCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCT
+
%&(!(&)!"$#)!($")(&!''*+'%'&&'((#*+*)%+"!"'$$+()#"&)&!%&+"%)#$(!#(+"*$($!+#!+&+)#$%"$"%"%&!$'"#$!$+*+!""$%"$)&#(&)!'$%$*%%'$)(#&"+#)"#+)*)&((&#&'!&%##&#*'$+))*($(&#&#()%#$%)+"&"!')##))"("*#
@r5246
GGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATCGAAATTGAAATCGACCATGACGNAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACT
+
'E:$.=4?'@.!G;"(H1E!G'*@>=:',H%9#,">*;?3/?!B%D,"'?FG+(),;?GA-&C<;"*@3+2.+)15$9:C(EE:",67-C'/&"G3#?5:CH'0#<2'/G11A!)6+=@5!5<3/4&"*E'<.(@&F%8H'G+:<+4H53.'H"'0GC@$'B60@.,$;+1D;>#,&*02H<7@8+G?8C<8:
@r5247
GGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTT
+
,/0@25*-/7.:904H*6:B*88C!D$G846!>,52=/(B>H=!A'/8+E>'83+G68<7
@r5248
TGGTTATCGAAGGNAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTG
+
BD(#$<7()&D,8(.E*&.5H>?C@BA-/0AA@61B-9-H=A%0CC*9D$CA7"'3@<0'D72D(8,88B?D@*A*)3D#?06)$3&*92(DE,<&2'E.
@r5249
ANGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTA
+
"!E(:'F+@!!(#>H@&C,)75'?+,!F965%5D9?C$140%
@r5250
GNACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTT
+
"%'8FE46@'/4-.-"'FE.&*9<1HA=)'7,6@.!(D5ADB9?@1!>'C2!8*47/8/,C5:460@1',@#*)=)1"$F=:"+3,7,+#E80;6;5&*%8!9;<<8"+A"G@<0@%;B"?4CAC$F=
@r5251
GAGTAATTATGCGGAACAGAATCATGCATGGTGTTNTCATAGTAATAATTCCTTNCNT
+
')=A/!0-8+=$=(>H>7F:1G(-6C?#H#1?6.-.#*HB(/35FA155A>B3*%;H4
@r5252
GCGGGCGGTTTTGTCATTTATGGAGNGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCAT
+
,C(6,(7H9"%A*(#>8%B.76/)"G$(E>+-3-;H78)@-#?443@'<D'.)75?'DC,
@r5253
NNCCNANTGTGAGCCCGAAGCGCATCAGCAACCCGANCAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGNAGATTNAT
+
%"&$!'&&$++&(*&"'"&++$'&$#*'$&#*#%$&+%&))!"($&+(+&(!*!')#"%+!"")(!*+'!!%$"%)%#%()'"
@r5254
CATCATCACGCAGAGCATCATTTNCAGCTTTAGCATCAGCTAACTCCTTCGCGTATTTTGCNTCGAGCGCAGCAACATCACGCTGACGCNTCTNCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTTTAGGTAATGGCGTTATCACGGTAATGAT
+
62"@"005(<E--/A=,$-G-H4++"0!D+;1)!=C%289"$3!5#$5!)?9/>.,F4D9'(2;C(5C<@"H*.&@",0$124%)8),65D#7B9H$*<FF:!1?995%4?D(,45<.6C01#'0C#-A#(6*89.A7!9-=.9-!<>H#A'/%40F32+),5'4G$&!%D&;/GB9F/1;HCD=,
@r5255
ACTCAACCCTGTCCGATTTCAANAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGNCCTGTCCAGAGCCGGGCGGGCGGCAGGGCTGNCGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTC
+
#-4'+@:D852C3#,E?,>'9C69!FE=1D)56HG'1<@6(H;(.E6079)%<=C,6DB=;0/E2/)/+:7=55A-.962G*H-@FA$)&;4&1@%!'G:HC4@'7*<C2>*(0G06"#H/,?")1(8#)2B18:@E?5!H%9+H=63%7,'))2F7#!B#E@87-8$0$6?#0H!297<,D7/0&+*:;(4*=A.7576%&969&2<AD2,&G,#,,1*;*F2FE0B"-CBDAC8$<5H*F0(7'5)?F;F@%@7#5!C(<:;/,*FF:B?3(%.6AE8:H1&A&:,F))&H7D9H))D
@r5256
GTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAATNTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTC
+
>G.8<8EG6G@4E@48H98-'0>4G1$3.*<-8;A&GD%1G1'25&'%%>E3=&B<$3G8=!F2.F:42/<4?0)C*5<'>,??+FG(=E#?F--+=4,*F9.!-&!
@r5257
CCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGG
+
H?%B91D173'D",.3>*7#.H%BGG#F?961'0:ADA$$=55&:=:BB0;83="=@1?AD8GD!7B9:6BG@C@6'<>D-<DEE4<=6F7@/(<"G/D$.>>.F$0C()#"--24=62;6=A@
@r5258
ANGTGCAGCACAGCATGTGGCGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCNTGAAGGC
+
F!'$F<F5FH%H7=977?()2,A1"+2D*C>H#?4(2.>#',G9BGAA<8(.F07B&6/!:C&$&F/-29"+"#3G>7@!'6#
@r5259
AATTAAGTGAATTTACAATATGGTCCTGTTCGGAGGGAAGAACGCGGGATGTNCATTCTTCATCACTTTTAATTGATGTATATGCTCT
+
C2$G)?AA(%-*G8CD<*08D!9'=&,&C(==B;F)A>@9'"(6C"#3(!,14$()#;6E(&:E(80+,*F(#<>@$,7G8;.#?!6C
@r5260
CCGGCGTCGCGGCACTACNGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCT
+
<1<"2('E.?'<;(+B:+)?*B.2G>BFC12E9*>FD7H!"1:HGC">$A:B0F=2B@/:?@'
@r5261
NATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCT
+
!B)!%F;68GG)F*9C)DG+H-2$$%@50?(9H+#*"G)+G9H?.$="GA>%#+&!<@&AA#.G=&6>*FH7?1.G-$G%AE8$18<EF2%6'&4!<!"<.:D6-%
@r5262
TTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCAT
+
7%.-/"1"%-D/,H*H1<6C9?BB&*<,,H0-$93,$5/#718F>!+E%0"C1
@r5263
AGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCC
+
/#;5EF*($5$7<.F93%@39!<28#D<C((3G@/F*.6!!$2E16)05BHG%GG3>16;&.H2"
@r5264
GATCAGAAATGGGATGAAGGCGAAGTCATGAGCGCCGGGATTTA
+
&,AD('B?B='(%CF2%A2+;#!HD/5A=+3G7.H/,?E$&&$"
@r5265
TAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAA
+
$752G+>"FF$?;'"F-+D,??.6<E,AD;$>5C&4/0("2+H=E*$/7@$&0AG@=*@/0<<&<#G6#(51=B8?1$(A-&86F96=$A(ADF=53(B?8@8AE:1E8?A8A!)522:29/5&5:9+3F;C>GB39:548,7#D*";29C1<"%4?H4.@&;E7!$*2/%+>4;3D'HA$6$H
@r5266
CTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGANCTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGC
+
?=(7F77E)F<%)..@54#1;1*)*':=),:3#G"'-9A&2"E,D''9.3@,E5D50./02,7.=9/7$5-C70F/5F:<")0:$3?)6'=99C-1/6?D&(2&996B=!
@r5267
GATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAG
+
@;B?/94").C%>68F>:&:?'-93H?(EB264DD>2DB;)$-(?&2D*,9!4G:C2*A=G&@&/(!0=8E,;G45B3C*)#8?5@6'0F<F7)
@r5268
TGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATT
+
>53"=!)/?6>38433$B@@)?>%G+9E:29=#!@05?!5G*8>B272@G/,;E.8F34EBH<>7D4::7B&:B)57B#F@91';,4@DABC7);24=H6A$)G9#D'.0#5"8D&"B6/"3-H-A251'F;:.#57#DC
@r5269
CGNTAACTGCATATTCTGCAATAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGANTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGAGCG
+
0AG#;536>E$*9!:+)5?C0E++(8C2<FH48C'E&;>,#F;5E0(<5*;9*(=72039(@'"HH?%?=C3:-*2&%70>)F9/.*?&H-+'?+"?:1G,,,HE'0?<FC(7G
@r5270
TACGCTGAATTAACTGGCCGCANCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTNACGGCGCTGGCAGGGCTTNCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAAC
+
D":?F$3#763AH-H9!CDE+)G"=?*:C:0;@4>1-3#/,3?@/)D0F.F0/<??)4<FH3/$(3?=99%=?:C76A&+34@1)2F744"D0$$*=*"@+/-*!F:GF/=+,8E?$,A;=?0H*'D$6)6,7A2*&:5>09=?&!$B6)>)<FD*1EC9;F3=HC7B(3/3*0(&?%A
@r5271
TAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTNGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAAC
+
H"E#*&<@)4@F*!#14<'>8)<138/?>@F2?6(07=FD32$B"9=913/@!&%.D2/B/4%A"E"B-6DH,?&&E,9A(083#4</5B88:?E3'(*;3/)?A=AG!8A!<+3=:A#<;(7E:7"#47A@/1;/H"5D/8.7#?<(55H#3H7,D-8D/>G'#DF40C*).6F
@r5272
CGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCG
+
705D"06&A6F4(,?E1.'H$+/2/+2C);A:*<7'$.?0B5=4/<7*=<C;6+9>CCB#"*""*C&1#$@F;'-/;333*=H
@r5273
CATTGATTTTTATCANTAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTC
+
A;A%4#:G?:!?=A3G/-15+D%+%',6&B*(6G6;8HG+B#E3AB<3&,@25(>E83"#873,+$+.,:$E
@r5274
TNCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTT
+
'*>A-(6-2%"2(1+5-"DA*"#.%0%E#7#"8%8@@&)/9$"#23C1!
@r5275
TCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGT
+
"6B*$@1/."3%1''@2>H-E4.8BF/%8@E2?),$)EF-(/"=6>!.B;>4!!'
@r5276
TGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTC
+
(')=:!4G?*<@$D#1C+G.DG08)<2/B&>?,0?$-+<EG='3';H&1AG$0,6&<GF9%14#(!5.-5C,A<23:(5
@r5277
CAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAAC
+
3$#@3#6!.2D()"B5%5B8":<E;$?=EE-67>$5-!'&<"=27E,/552GG).;53?,"0=/E'&==,H,#08'=AG;4>8(H'"!C22A3H)@/6@FA#;#('F=-#)?8<E'+6>'#5E&E8'007>$H(96-:',?A*+%(1=(>(C@4EH.!<*2*<:%A?*"%C"!0B@(
@r5278
TTTNCCTTTGTATTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATACCTTGTGTGCAAA
+
((*!*$**(&+$#+))$++*"('$)%$(+()&!)$#")++""*"%'&**"(!#'(!$+$$*&!$$
@r5279
CACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACA
+
D+#(%CB=4E.;%6B-H!>41%G>6)$F(';D$A(?@1=$2
@r5280
GGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCA
+
3/F%+A=*C")3;A..:;<D@(,*B63/49?3!&G2H;D5H29>;":5/5$4/@!34(:>8@E#B@!::F=#F50&;5:!&+
@r5281
CTAACTAGCCGCATNGGGNAGAAAGCAGNAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGA
+
**%'#%$+*!%$$**"!)**#*&*"!($*&&(""'$$%*+()#+%+&!&(%&)%*$*+'*"+#&+*$"%%##()""&)**#")$*'&*
@r5282
TTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGAAGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGNTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTC
+
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
@r5283
GGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTNATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGC
+
G$(>CC///780$#86B@B1FC@*+;!$%<H**2D;/"(1E9$"#1#.7-%;6#$!,>(D=1E1-9.2;G97!#<,,69A5>E:3+F?D=;%-+A"@90A30?%C<E.-&<83,2H'F=/EF/D";D$0+8<E!,+E3006A7+<FB2!:911+-=056&0"7(-,":A-#8C<(05B97.69'3B!?D$>@;-=DCA=1;137G6>+60%<0;3-3H==6:,!H42H?:D'G6>?2#%.
@r5284
NATNNNCCGTTTCAGGAAATCAACATGTNGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTNCAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGNTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCNGGCTGGAGATCTGCCTCGCTGG
+
$&&"(!+)$'*'#(+!"#++*)(((+!$*)##''&))#$%&!)#!$%+&+(*#))$&()"")+!++!)()#"+")(*++)(#*!%$*%*$!!($*&()(!%+(!")+)$))()!%)*!###"'*!+$()#!'&&*+$*"'&'!%#))&%)++'(!(")#*%!$*)&&$'&%$*#&'$(+#&+*"''#+(&(%'(+"$(%()(%$&()%)'*&#%)(#'$)''$&"(%"*%#'+&#'$)#)##+(!''('"'
@r5285
TTGCTTGATGTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGC
+
5C%;H/,B=8;2&%D369#8->08A6>5-<4F2&!8G",,C%2GFA,34<AFD
@r5286
AACGACGATGTGGTTTTGGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGG
+
&&#%%"*)%)+)$'*!"(+*+(&(*%%)%)")%!)'$(&&$++((&'""!')&"
@r5287
CATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCG
+
<9AC(+2;%G5(6?>%1B9G>+;E)@!:*)&';0"2%#B!H9";:1+'23-GG*)%D:%
@r5288
CTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTCTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTA
+
H/-H8%(=<A=4@:.(4F1!:!9+50G*6-6C%5!5,,94C/29H*F-04$.8&A96=&E-<!"">1,:?<'G,G;/=;#F<((GA&)@"'!?:2",>;2?*78>65*A-*&EE!!%&&'2/H5$D0E"3<FD);3<5:=8
@r5289
TTTCNCGGCNANNCCGNGGGTTTCTGCCAGCNCGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGC
+
&"*(%%$'&!%!$%+%+"%'+'&!!!$+$"#*$)(%+#$"($)'"!%#&!*((%#(&&+"#&)$#"!'%!$++)*!+'%*(!")*&"*))%(+!$')')"++
@r5290
NCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATNAATCCCTGAA
+
&+&+"$"#*%#*&))&(!*(!"!"*&**''%'!+'*(%'('#)*"%#&%)*#*$!!)')%"+'!"%)!$%$'%*))"!#"!+'
@r5291
CTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGNTTCCGTCGTCCAGGCCGTGCTGACCAGCCGCTCACTNCCGTCGTCCGCTGTTACGGTCANACGGAGCAGGAAACTCACGCCCTTCACCACCTTNGGTGTGTCCCATCGCGCCAGC
+
1%&A9D?2,)%3=B?513?G871C3?=F"8%G!#2)B?!:(C4?*:2D!E@G'..:&4)0<C#:+D,8*?;F1(=1EF/*9B!:44+%"D'H0->H3/8$-="?#H3*G"2@+(9G=E/9F1E6)A$1..!>:6B$0DDA/'*H$>B5(7/55G58*-$B0=!8
@r5292
ATACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGCGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGA
+
%#'+"'""+&&"!"&%'!$+%&*(*'''%*$+!$!*$''''*%+)'!%%&'%!'&)#$(#!(&%!+#+!%(()*&(&(#&+&&&$"&)#$+%)#&&)##"$+!('""!((+"**%'!!'"#+&+!+*$$*"('++($#"+$'")%)"&$$(#+)&"+($*(($%+
@r5293
CAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGTTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGANGCCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCNATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGNTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTAGAGGTCAATGGGTTCAGGATGCAGGNGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTNTGTAAAAGATAACGCTTGTGAA
+
1>%,BD%E)(HB#=4!8<AD*$5E=!79E'22@#@0@,='#"(5-8H@01D?H7A:8::H$8A9B?3/.:B)'<E5G8#C:10B?'7+<82+*+18G#B$:*,9=;B1:8*.H7&",B%B*(:-4?>GB!H7C".83*.E,EA31#/C5045?G"98HE*G;B#F@AC?!%C)'-6#*9A@3($)#8*H#9$!=*/3.G;'B>%#2+1006"4:!*?F>"+E'%A8@4)1'=1<C&?&/>*F:>:8CA//;A24?$6#8.A6,2?=4A<#/$!F$@</>:DB<<#<F5(./#E1G%H3BC4GA1C84,.666#3;?%F%?27<->/6)4"0))9A=#+6*>6&>"FA816-:AH7F!2H>)915,';C+2<!2#-;:*&*&6'2#3$D).+=>B;#7H/;%+E%D2?E/,3!@.>
@r5294
TTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCN
+
D*.3E89"$HFF#:0+%H80-3/%$3@6/<B"&10?E*<9/$='0B;97<&H7-9@,.9)=A&::B5)%D:54(GF!&?+E<!!=A%'!/$A<',6G.A8)*?,:-=C/+8
@r5295
CCCGGTNACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGC
+
1F(B9)/;E$2:7F(9DG:+B,A%DH7A@3??G*D.C1F"01A.13#GH".:"$DE6A+=2*/F(FG:D'&7744H:=!F-567E&,1<G+"-$$$()<,
@r5296
ATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCAC
+
'H'8$#H63E-!$BG-+>%8<)9756?1'!9D$<HE4)/7@$86GE
@r5297
CATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATGTGCGCAAGGATGAT
+
%+$,.!7G9/+=66"<-,15.9=0DCE%@A1=@'&D+"-&+).'84C!C'$+8D/,GH24A46!)<0"!-H<.(24+-(-H!D<."4)B8/<23!/D2"@8+#%.8:?E'@)6A@.&D5.4/G:4
@r5298
NGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGANCNT
+
&+")%!%"'(&"!*'"(+'#%*%"$+"%!'('"*!(!(*%$#&"&&'$'&)&()(++*"($*+*(!$!*"(%""**$+
@r5299
TTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGATGGATTCATCGTTGGGGTCGGTTATAAATTCTNATTAGCCAGGTAACACAGT
+
H&;#19F-=19;(D=&%75F!-/<.7$=&;B.;!;)HA'B='F<C+&;*,@,CE6H1H5;>A'"D";<0=6A-G2+:0)23G7%,47)E->'
@r5300
ACCGAGGCCAGATACTGCGAGGNGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCCGGCGGACTTCCGACGGATGGGCGGC
+
D1H4+C4!66GE:$A6.;1%@A.@2F(D53.<*F-E0D;&$.**$;*/108')7%AF9&8'7((E6=F.":G6E'C!#+4!,!&*>FAG#91F!44;/-)(B*F@=D>G#*$-AD$
@r5301
GGTGAAGCTTCATACTGNGGAATTTNNCNNNNCGCGGGATGAACCTGTG
+
('&$'*"%*&**&*)*"#!)#!"*&$#)!!"&#%**#*+$'&)'(")+$
@r5302
NTNCNNGGCAGNGGTNGCGNCACAACNAAGTTTTCCTGCCTGCTCAGNTGCCGGATTCAGAGCTGGATGCATGGATCGAGTCCCGGATTTATCCGGTGNTGAGCTATATCCCGGCACTG
+
!''*"))#%")$##!%((*"*'"$!%&+$'*#+$++)!!$+$+!%"''!&$##&$#)(!*+*"!)*#&+"$%'+&%)!%%$$$(!'+!%'!&'*"##!+!(%)$+)(+)$%$%"'**("
@r5303
TGGCCTGAAAGACTTCTCTCCGAANAGTCAGGACGCTGTGGCATTGCAGCAGATTATGGAGCGTGGC
+
0>3CF2>G4501"HG/?.A;83/.#9GF<63&8A;*G(05@8-8)8&A5=@<1/>1+,=*08%-"$)
@r5304
CAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCTTCATCCGGTGAAGAGATTGAGCC
+
7+&3&G!,E-/0:17(,,;'5=!)<H;).%G>(,',DH"B%:2D#-38E?/FG0D":%A2*9(E7@D/%-.57/H!@&,20=-/G>>4)3H<">B/4%E4GD14";4
@r5305
NCAGTNCNTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCA
+
")%$#")!(&))+%)*(#("!+(#*)&!$&#)'+)!''#+(%%(%%"'(&$*$#'&")+$%
@r5306
CAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCNTCCGGCGTCCATTTGNGGCCAAACGGCGTCTCTTTGTCGCCAAATNTAAGATACTGCTCCTCCCCGCAATGCGGGCA
+
5':?(.',/E5>,;6)&@7-!C%FH5+/38/>3&A$ED&#(+90"5E#-;476'E)9()'<%:D)*!C%'A63C'%9@??-6!#=C*45B9<(!!E2%/C2:FD+"*64C>H.-=*3CC
@r5307
GCGGTGACGAGTGCGGTCGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTNNGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAANGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGT
+
+(('''!)''#&%%##%$"$(!$)&))"%+!+%$%$&*%*!%*("()*+(")+"$"#'%)%&("'%%"!)!("!'!)$$#$###")*&%%'!("*''!!'*+*#$'"*#%'!+%%('##$*)''&'&$+'"&)$'#($$(&#$&'!$)*'$'&"!*!+!)$%
@r5308
ATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTT
+
*BD>(>BD9DH//6>FCHF-56>@6C6H);3$;(?8&$#1>?".'=/8$709@<DG?
@r5309
GCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTNCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTC
+
..GB<4C4BC>(<1AC/>,&G0,2=?!F4<2=99%E2.4D+4.5-3H=?+C=-'&>4#1$8!?@*F#E$)'F&:79"=*4(?,HC
@r5310
ATTGATTCAAATAATAATCAAAAATGTACTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTC
+
3:;9G8325:@(48-F&+:@8;#DA3=C1&3*C#+<AAE18!.3:B.H0-H9@;H%*CC,E-E?B#>:+/1)'*GF.+F;F"",5.#2G94A*H6
@r5311
GGNATNAGTGACCTGTTACAGAGCATTAGCGCAAGGTGATTT
+
*$")&#(#+#'%"'$$"*)#*%+"%$*#"!(%($!''&(%!&
@r5312
ACANCGCNNNGTNATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTG
+
$'%%*%%"##%+$%$%++###+''*$'!&*%!!&)"+$+$&+%+&%(($%+*'%&!$!#%&'&!!'&)+$++#&(*#*!#%#(&!*
@r5313
CTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAG
+
A".$-'+&1(3./465B3-"50<'H-D3B)>E5/")*1!D4&'44=E:(-82-6&0443
@r5314
GATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAAT
+
)-+@#%=@A>=H<A($>C@-A3>GB-5-$<$&!H5:7<GB,1;!/6/5D
@r5315
NTCTNCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACCTTGGAAACGATACTTGCCCTCTCTGTAC
+
&)%&#*+"!+$'+*!)(+"%#$*%()++'$$(#(+('+)("$+"+((')#+$$&(%&"$'+(%+("$*$)$$!&#*+++$$%*
@r5316
ACAANANGGNANTNCTCACNCANNNNNCNGGNGTNNCTTNGTCNC
+
!!"!""#!"!!!#!!"##!!$"!"#$!!!""!""#!#"$#"#$$$
@r5317
GCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGTGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGNGATNTTTTTATTTGGTCCAAACATGCCGCCTT
+
)"'0E?6(.F*5C*0>3!2CDGH98+5/()2@.%>8,.5$E,5C4*G-,@771%</#-AF5#3G7'"0E7:3/4<)H'H9>?AAH;F:0F%EB<F#=#*,;4/GD+-:.9
@r5318
NTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCAT
+
!F9'3AA<89+3*@1<"971/H-=09H-$-":(@*@1AC*>2<=2H:8GG+7:>F57.E26+&
@r5319
CCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTG
+
G'&=(51:C)>8B.#:?11A'.?//F,E6EEA6.)5+';?..*A2@3(91DF>C5!-
@r5320
ATGTGCTCAGCGATTTCTGCTCAGCGATGCGCNGTATGCCGGTATGNAA
+
:H3@@=)>)C9"#H<?,G)/>/8?9,-G)-HE<!"C:,&BD%5D3>19:
@r5321
TGTTCTGCGGAAACCTANCATTGATTCAGGNACAGNGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAATGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCT
+
A50')H'@(%.@3H:2;$H$.)!C=DH&E*-1=)#D"!@.;<C!B&E*&?>,!)=2"45FE,<5C#388A1$4;+(B*++DG72<?&C$.,;%C0-F8$@5=DD4?$:&:--H9.D&.$!/?;%+H0+8$@<23E$,%@(@=E.7C=#G2A01:.!F+?*59@+1)E0?/,*A'6&@='$$EB,#A>;1"30/3@-
@r5322
TCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTNCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTNTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCG
+
C4F#EB?DF1<&.?B/"@#DB10?=%7EH:'/G@E;@C%=1%@+6#/7=E9557>/'";FG506'<#0C<*%B7>!*==5=$/#'<4,:+)-4>-?C=A!D<FGH<2/=GFED+9,$1,=-!>/&@4C6(A"!-=BF*+C+;94C*7*E-+E?)G:1,8;3@0*+'!/:@A$#C)H0;((.'@@>=56414)*(0<,.G!./!:1%<866E+(7D!/'F#=EC/572#-=#8';F5*74%.BB."?BG
@r5323
GCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCA
+
/$'<>3>+287!F/1&1"+6??,A3%1F@A,7$-AC.$<+F@@CF
@r5324
TGCATATCCGGATCGCTGAAAAACAGGCTGAGCACTGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGNTACTGTAAAAGCGGTGCCAGTCGGCAT
+
+(#&!+!#(%'&%+)*)'"''!##%%'%+#!!'$'$"*(&#$+$("**"#%(!+$%+)*&!*&'*)#%%''$))#$$+''))%#&"&"+"!+#*&+&&!"'+"&%($#+!**"%(+%(
@r5325
NGTACCGGATGCAATGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATNGTCCAGCNTCGCATATCA
+
"F&G5FB);.HE&1-E=/627H?$;$,&(%&201;0%F;G=DGA@7-HA2)2%H6<G,#/%<G75=&<*?85+;!1G*CC1G$:(G/,/)5(9C#H8<A$A%D0'95,8C35
@r5326
GNCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCT
+
#%'+$$'()+"&(!***!*'#+$+)%"!(&#&+)(+%)#&()!%)+%
@r5327
NTGNNGNGTCANGNAATTACCTTCAACCTCAAGCCAGAATGCAGANTCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCA
+
#()&*($&'*("**!"+*#%(#%(&*"*##))%")""$)&*$%*$!"$+)*)+)$+%(+)$'$!*%"%"'&##)%%*"%++'+!(
@r5328
GTCGCGAACCGTTTTCATCCGGCACAGTATCAAGGTATTTTATGCG
+
6E6&=>=@;E0=?$@/,5,D"@D+C-:B6F@9>8/)C(E<#058*-
@r5329
NCTNGNATACGTNCACNCGCTAAACCCTGTGTGCTTCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGT
+
#%%"")(*&)(#"'*+"%!)!%+&+#&&$+((('&+!((&)#$&###'+()"&*+$'%*#!**!%"+!'#'"!)$%(*$&)%#*")('
@r5330
TACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGG
+
42G6:<,>#FEB&#)F;"?F?%B.803)@@E:F0;D"?5;?C#)(<-',==5
@r5331
CNNNCNNNGCNNCNNATNCGNGGNNGANGGTGNNNTGNNTTNCNNTNCTNCNNT
+
"$!#$!"""""$!""#$"$#""#!!##$#$#!$!$$#"$$#"$#$#"$$!!"#!
@r5332
CNGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGNCGCTCTTTAATATCTTCAGGAATTATTTNATTGTCATATTGTATCATGCTAAATGA
+
B1<E2A6*&0#&"G&'2%.,9'4<+&+#$<C!?95H"30&!;=C#4?5!A-4$/,?4(+?>(C&&87=/H!B*40#%)'1@52)!$5/1.);?(,$7
@r5333
ATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTNGTTACTCGGGAAGGGCTTTACCTCT
+
7:'E<=$,;.7-!%>47&-F+0=GB':9"G;59-4,4:"6GB7<.BG@.-(!1195B)'#C,&0,";F/1-98+@,)"8G,'8(C75:H>!;=;CE.-,A"-:A!!(<<11:-(;$8##CD15-;F0;75@3G
@r5334
NTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTG
+
2(4/@;F/5H@/1.3+-0%F<*.>G6-A$3D#*FG'D!),-A.*41,6D"3/+6F0/"4=@&??,)#4?(>C=,0F=/B$:4>/5&E1D1:*@8:9')2'9=>+)<++);DHA811H=GC86-H3";3)89!A"H6=0
@r5335
GTTAGCAGAGCCAAGCCAAAACTCTAATTTTAATACATAATGAATGT
+
D>>&69B@2#CGE='#22+@0%A+"/9B-<0"&!7B,=?**A23&"$
@r5336
GAACCTCCACGCTGACCGGANTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGNGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCA
+
F0,B"969.GD'(B#,>(,F!;<46D"5;BG%96!-,%!7>E+;,'0G0)+C*%7#,<E&@E#7AD&1;)9E57/?2*C-!H02:7:D;F>%'@87(5A>@$B9#;.A6&11F!8+!,#;/%BD-&H#;#'H?F)'#//=D'('%7*C(
@r5337
AGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACNGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATT
+
.-$?F>9?7C5E"@0>58$"/*E?A1,7!($@3ED=GHC356G;4B6HB*"&?13F2!2+28%A.2'$::@507@G<E*$B4&)G<"*C,,
@r5338
AACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAA
+
64@A)8>E"9.7@"8&-2%9/.@@6:D3"8'0D<%,48&74@>D(%,5
@r5339
AGNNTCTTAAAAGAGAGATCCTGTGTTGCCGCCAAATNAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATNTCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACT
+
')&&&%*()+"%!*%#%'&($*$&#")&%*'&$"!!&("(##)$$('++#(*!)!#&#(''*'&&!"'*+%%'&&("$*%+!!#"')!*')&+&$#!+%&(")&)&'!("")(""'!+("##+'"'%!$&"#&%!#)$"(""&!*'+%+#(+'"!&$%$*%!'&)%!*'(+'&&($$'+*'%+##(#"()*"%'#+'+#&+!''$&"%(%&$*%'*&'*$"#+"&)')%!"%%$"(*%!((+$#")#)$#%'$(++#+$*'#"''&&%)+$+!#%!$%""(&"(#!#"#%($*&$#)#("')%!)'!
@r5340
TAATTNTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGA
+
'-?9C(BG+,E8=4@C<=)G*::1GB@9'!1+(G"!2HAE1@;,?@:
@r5341
NTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGT
+
$-.*E0:(*H(#HH&77!#9??#2?#0$<?CC=C?-;2=!?G323CDE8%2+6:F+$5!A3/<-@>#C%'$1=/=4*=H9F+E=+)3!3>4<GB(3%'HE>>1/<D(A.7F&F5'&D
@r5342
ATTCCCTGTTCCTGCCAGTTCTGAATGGTACGNATACNCG
+
G,0-+(,5023,<!H3H;GD$/*A/EF,B=&9A$5G>02$
@r5343
ACTTCCGACGGATGGGCGGCNACCTCGCGGGTTTTCGCTATTTANGAACATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAANCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGT
+
D2'$9B6,/.1&31=4-13/E4'%()62=DE26;-*-<A@A+<B?5>(C'>659@,0=>>8<CB6H,6+:,7<2>@5:=2$HC1-1/;%@(158&B:#5BD<%/890?+22*E8%%&%3$C9337?)-&ED9B4;)F27B13(E$G6H-&@D;6$4:#="&0C&F&0+2&00&*6;9@):GD9:',,=$
@r5344
GTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGNCCGGCGGCACGGAGTGGAGCAAGCGTGNCAAGTCCACGTATGACCCGACC
+
$(*+*$(%((!**"#"*$+'(&!!#!!#!'#((%++$'$!"+&+&#&&$&)%!+"%!()%!'*&*%++$!)')+'&('("!$'(%""&$$()&"#((%%&()&$!*"'!''*)
@r5345
GCTAATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCNCCACAGACCAGCTGCNGAACAAAACGCTCTGGTCGTCATA
+
!!()'*&#*+('(&")##$"'+$"#*"#"%)#''"%'$"*$!&!)'+"(##%)*!$'$!*(%#!"%'*$*'&+($$$")!'()"%('+#*#&*$(+%+')&&%%'
@r5346
TGACACGGAAGAAACCGGACGTTATGATTNAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCNCAGTAAATA
+
-A414-<:05<*505?5%-02&!+='H%G9!32?/4%/%!)">;)0$5'$<&6=0*H-75>D/A9"G/"BBBC"#
@r5347
AAAATTTATAATNTGCTGGCCGGAACTAATGAATTTATTGGT
+
<G@B82,G+.1)86*($8&F*B-G2&=4.#?@,C$*8'E+2D
@r5348
AATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTTTATCT
+
(%&+)*)#*$(*#*&&#()"#&&$!%"!"%'!$++&#")$+%+%'!(*$!"$''%)!%#(*!)+*!!+&&"!#"&"$*#(&'''+)#!(!
@r5349
NTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCC
+
)+&'&!&)(*''''#$'#'&%('"$(#"#)'*'(&"$&!#))
@r5350
CTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGT
+
9%=!C4**"FH<)<0-F)#4=3+#:2#:"*H"/-+!</*(&6G9
@r5351
GTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTG
+
:#;!-G0%5-6':&B060-40;#G3<B:BE9+D2BGD>)+3;<$(H0H?3<+'*.?29;4.>7/&57$?
@r5352
GACGGAATATCANGGATAGTCGNCTCAACGNGGGTTTTCATAAAGTTCTCGGCAT
+
E$>&*-)6@;-4/0C<"50#4'H/+@"H;/':';+%DC,=:;7>D>(?/7A+='&
@r5353
CGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTG
+
1G#28(-#HD+#/'>(8?-8.">/-$D=3:H;):.;.D@,?4.E7:G;A#C2<&7.!<B)
@r5354
GAATGGTTGTNGCCTCCACCATGCGAGGATATCTTCCTTCTCA
+
'<@0%7)2*C84"5BB(*)5H494'+:,$054,3D?(9576*8
@r5355
GGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGNATATCGGTCACGAA
+
%5;6?<F>,EGH9#8;3C).=2)!"<-G.?+E.@3!DG6#.7:"H.B%'+00=
@r5356
ACTGGCTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTT
+
;/;$-1+14&20*3,:#*57E.H*B@@G*5++1')4/*=<G"'4<&:59!/69,;B)D8$"3&881<=:;@*09<8:$<*%4.#B#57.-=*C;&#HE
@r5357
ACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAA
+
>6"*-*+2.01,3"$=0AF5D33B+/!?1;:#!D61>/$"6/@"$.<,4&#27"(H&HDDA&/E91;D$6<H:8,G:;7$(=$7DG=:>+31A1A50H)B4."D4"!?9!
@r5358
CGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTA
+
+HF=2,8%.8&06A#9@>94)?(,-<945,E#/B#H)FA,(,AH.+AD8*),631'1EF#&=-C5
@r5359
NTGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTA
+
"2F2/:&AD5,59&(:5;E&8923!?":>1D!$5.A%;5%*%A<=:-#1-/D.:H@FG>@(7',+8026
@r5360
GCCGCNAAAGGAATCAAGCAGAAGACNNTCATAAATTACATGAGCAAANTTAAAGCAATAAGGAGGGGTCTACCTGATGCTCCACTTGAAGACATCACCACAAAANAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGAT
+
'"'"*!'%)'+"$*&+'&!(&+!#++%%+&+"%'$#'$()#*)&+$()&)'%"#"&"()%&#$$+%"""&$+&)&)$#(&+!"(#()*(%*+!'%*"#*#*"+%)$(!+'%+%!+(!**"**$#*&%(*#"#'+(*'$!*"!!)'&##*"'!(#"%!'"$#!+'"%"''$"*+"(+"*#$%**&+!
@r5361
CCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCNGCAAGCCAGCGAGGCAGATCTCCAGNCAGGAACTATTGAGTACGAACGCCATCGACTTAC
+
)219*37;%/!;E;>/8.!G2EH!<>$&!%1:(A:1<7200CCB(A8E0!GG95.)18'?F0!((>5503$7?G<B7/6'G%BF8*"@15:*;*'8@3<@)7#F94G99$::+;#%!6C;&C34?0G0%3.+5<')
@r5362
GATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGGAGATCATCNACGGTGTGTTCAGCCAGTTACTGGCAACTTTCGCGGCGAGCCTGGCTAACCGTGACCAGAACGAA
+
/-G>=FD88A*A#<3C.="'F":<0<FD2,'<?D-2FG0;H6>D7;6;!>*1-1;?E>2%19;;!H/6@,;AG&A7#F,0.,C-);?+#:2C"G%$;8&-=@@.6)8/9A<-?6,)B?#-;7@31'3G.B59!.;52,0.F?1,!5(/*3E(4('&+G#!BB9#*@
@r5363
CCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTAT
+
E&=?4E5*!>5;(4#%7#:F4@>76(2%$F%D$3*?@#GDDE9.,G?)"5<&'#!%C
@r5364
ATCGATACATCAGNAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCA
+
?!3;?:&,9;!+=#1$A:84H%)16,!-5,>E>9:-?,*6DF$+<G9F)C%EF/-B;=/'.49.H8(28G9(+D0
@r5365
CTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCTAAGCCTGGAAT
+
3?2G:2F-DACC"*>4+D?C5F*-;><47F6"07H(2?A8FF%$B(F=#=*G76%85);&@A7C"E:1E7C37);.:/',*"@)B8D&;C!E-D,B>9>*+D'9(A!029174+@>BD57/EH(2'0$9
@r5366
NNNAGACTTTCTCCGTGGTGAAGGGATAGCTCTACACGGAAAAAGAGACGCAGAAACAGCGGATCAAANTTAAAT
+
('#A$&=C!83=?4!-</7>B43&2@(.9($3$,:+$91##3FBF&56G5%>8C7A7547)1+4!+-078<(=-F
@r5367
CTNACGCNCGNNTNCGGAANAGTTTTTCTGCTTCCGTATCC
+
""&#'#&"'&(#($+$+!*+"*&%*)+#(+(+%*)'+(("(
@r5368
CGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACATTACCCAGATTGCGAA
+
1$%'"=>B"F3#&2&B*=CHBB7D9):3.G((6,FD+4/3H:8'!8DAFF%F->.?!
@r5369
TCACTATTCTCCTCCTCTGTTGATTGTCGNAGCCCGGATTCNAATG
+
*1;5:$C@)8+3$8%)#81GF1799F%A*>?&;>$+C"*<D28?*;
@r5370
TAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGANCCGCCTACCTTTCACNAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGT
+
BC:22&%15EB=2)(#"3?'05*+6'H)?C%%GB==%A9H=8&;)9(33GB#D>4G@D6?C*#G"<BG3H(3AC>5@@4;HG87D@E6</A4+=4HH!'5-FHA2"5"8+@381'$1.&++B)%*#17H=!H91&E:A6D=1/EC*(F87966*.?>3".->0C'C>+?HF/@G@/$:6E$535C-H)H<+>=8*BE=10(DA4.D%F)7,#)
@r5371
CATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATNA
+
="@!0:(E:9!A":+2%@+9,#53>6>F*+869GD<<8B*<DG&;@-)+?A0&/C;3-04..:)
@r5372
NTCNNTANGTNATTCCTGCCGGATATCCTGCATCAGTTCACCACCNGNTCAAACTGTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGAGCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGT
+
!%$!!')#()#%+%!%)*&)*+""&&)$$"+%&"!"%"!'"##&*#!%$&++'!!!&!!$$$%#+')($!+'$)%!#!*&"%%))"%+#"&()&("&++!*&**)#('&)!$)$&"+&!)&"'!+$$$!'!*!!$!'()+&)%##(*&(+!$'#%)$$'+%#$$+#*#$
@r5373
GNANTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATTGTGCAGCTCAGCAG
+
*&""+*'(+"!+&&!!"$("*()"'$&)**+&$+(!'('")(!!#*'*%&"##$)*
@r5374
CCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCG
+
2/E2!D,69!498D/C,/))(-F*%-$@.(->#+??:.46D4$#68A@<&#"#?(;712<F>.<&#=@(;C,
@r5375
ACCAATNCTACCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATTCAT
+
-9:,+)*#2FC4$0$$D(FG!"E@A;DF4BH;3F4<EE/#4.A*!<H3CA,(HC!&<
@r5376
TTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAA
+
H$9C:1B?*H<E(;#3)>,(6*%A)H,-)*"<?;74;7$=<%;DA=(F$E)6A+/??>4<C-G0D6A=$>F,6A-HC*(D8.D
@r5377
TGCTTAATGGCGGTGGCTGGTTCTTTANTCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTNACGAATACGAGTTTGGAAAGCCA
+
64'@9=2%>@.--G)8!**;/9%E'!-+CFB>,?5.D,%9;&1+H*8$3&1C3*4:04:=2$;-(+*)G031&1A14:B,.,'7#,H'!":'D/;@<)3B!$D30A?"?50A0+$"=>0F'(*+725"0A<:-!=7B09='+*&@'#<,%9,7H-4/$#3H9AAH+B+5:#':D+B
@r5378
TGACGCACTGAATACGNTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGNGGGTAAACAACCGAAGAATGCGACACTGACGGCNCTGGCAGGGCTTTCCACGGCGAAAAATAAAGTACCGTATT
+
.>%3)&7DG)5:$D&G9)&?B@43929%%+3=-F5A1A+",32:2:&@+@#B=76*'.">7!7:$.2B0;/&!!(+:,;>"3.65G2'5;:0("%!G;2+/%6F32@5B;FG2C;@/,-<-%#3)(<HC."3(!**@;4+500D/A2%HE+0<-C1"=
@r5379
ACCGAGCCTGATGTGGTTAAAAGACACGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCA
+
>D:@+8H+:$#;%G&,)EF;$2*&3'C,"<3;*<HAH2FE5:,:D#>(+5D:1/)/,41(-=G48+=,:%/3)C6)2?H7"E-.)/A7)-H42D3?B!;8!=8C='
@r5380
NGTANAGANTNTAATACGTTTTCATGGATACAGGTTGTGAAC
+
"*(*#$&%!%$&!)+(#)+*&!")#&"$"$(+!!''(!"()(
@r5381
CNNGCANTGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCAC
+
)"$')*+%+$!+#+)%%*')#"(+#&%'&$'"$&'$")!)''+&*&"(%#%#$!*''#!
@r5382
TCCGGTTNTATCCTGTAATGGTGAGNTTGCTGCGGNTGCAGAAATTANCGTCACCGCCAGATAATCAGGAGAGTCAGCGATGTTCCTGAAAACCGAA
+
5-9+4&<<8FC%2(E!H37B>0)@@-F/@>A.(9')D"%%286"@?8E"5(F!!*8!F?DA#D2*#C+%+>;1$'F,-@H'B*3F0"C@8G;4AB)B
@r5383
NCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTNAGGAACGA
+
!(>#2D3@-20%4<1/+2"#<A2/F4,!74A#482@A:1!"'@C,0"".
@r5384
GGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAG
+
%7D)(4<$G@.8A%5"FFB3)(0;/E-<+75GA.:3.+5-/%B?@916>'?-<E:(2::.*"A9H
@r5385
NCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGNTGTTAATCATTACCGTGATAACGCCATTA
+
*+#&'*&%)%*&**!&%')!$+$#+#*!"$*(*#*"%("&%+!%##(*")#)(#&$(#))$&*'$*!"((+%
@r5386
GACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGC
+
8>!;:4<=&<,'H;2DF?2"@?C=C>5*85$(3/25:'>%.=C.B'89(GA!'1!"(45/9:AH$-#?):A9:E2B4CBD"$(7/1;G53G:601>>;,H5&F
@r5387
AGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAA
+
4!C16DD6$*>)@=<5GF%-)(8=/>AG8CG1:(D**E>-5:&C=%;CC0,H@:D?&8&"6,E27G+A0A4/34!$=2,)3+*!#<HEE.C63-D-H+>
@r5388
GAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTTTGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTT
+
@$7<8)1,D@+#8#=:9*BD71H(EA1-".$F#2*F$%@9:/$55@&:"+4>E=HB'B?%40!-7.5.(*="/)0//6):9$:C,%56;<4"0<-G#"HA2-.#+,*&$B#$;:/8/$"&0%")H"*A7+,&1*630((43E$!AD1?E:E6)55(+&F6C-$A13@(15",%4:(%$;5-&+
@r5389
NCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCNTGGCTTCCCGTTCTGCCTGCCGGTCNGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCC
+
+':2G@%8!8D::B--,<"3+5;8(F9:"4=$%>"23&%*.+!6'($:BC768@?8*BH?#C?:@:3G/(>'9,A.H)-%H'2A<.99,;#3E-+/D&(3)84H8@:B>=3%'=,F#7@1#63?#;EDEC$/1#)<"+#3@7$':56*/&'C1@*#:-A>"F!;>%8<71B?EE#&!$-!6F2
@r5390
AGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTNATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGNTTTGTTCGTGACCGATATGCACGGGCAAANCGGCAGGAGGTTGTTAGCGCGACCT
+
10G<'5817F#+*##7,@7+1;+1=><4GD"9<>.+D*"7D563=G#-;&*G1$0A395$64A'B4BC$!F,,2,95>=@?3?<,:675(6/3!H%(;6/1.62,8G%;)FHGE?+C?"$485C%-H:H;)AEG.=9G2#G2/5H+A)$(G-@<%,2F))?'2#":9G=%AF1=9;5.7A.D+5=<9?'H8/:4D?CC%$'68F-D&.)D#<A'&52$9(=<03C@H-/>02>?0&&:1/H?E;
@r5391
CCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTCTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTGTGCCGCCCTGGCAGAATTTTCTGCCGCAGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTG
+
8DE,$;!G&*)7@@-6B&D>2A3()(3H"@:"@#*G6*59E9$<A!=5(@.<<AHH$H!F4E":!:D-8-?EFA'>=3-&=*2&<4&'!.7(;7B.$#H7'%9D3&45@%""1G0F5)D70F66:>4'HG9F2E-"D/633"?&:=7H70!8!A8:!H214=2&F("C*&=HH61F'/>H2@30F9!7';53,C)F:@G=6,*@>52DE%
@r5392
CAAGGAGGTCAGACNAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAG
+
FB+6F"=@<;:D"8.0,<%9B$B>1B<B(:/5!B?>%+4EE&79)46/%,=%)/@=2FBC:FE1@(9,:70?':51#@@B5FFE)A/FE
@r5393
CAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTG
+
(A1F>6#"H@6)5%@766001=9=(<$0HH/.9'56(3G.##>HG#9'FF"&9GE;-9/!4,AF4E4*-),C;FC<+,H#2E/$:->?/B5/&:E47'4-6$9-#%&(*8>+C40!#0@7
@r5394
ACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGTCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTC
+
B*;,3G8&!#"/5$#4!&('$5;EA6&A87CB-%0=)83/B/E'6$/7,7*9F59C0AE>@C8'?!'.(B)-1>F&C9*6EBE2E@:B49,779"8@,49:A%A25H<DD<(96>5"-.39-445*)A:3>DA11;=>8F$=<9>8HGD>&4<F:<@")9-0>(;3)@-<"!9"D-2=/H2)HA*;0
@r5395
AAGTCAGGACGCTGTGGCATNGCAGCAGATTAAGGAGCGTGGCNCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTG
+
)+)'"!&+(+!+"$*%'$&#%&!(%*(+)')#%&"&)$'!%(%!$+'"#)(%+%""&($"$#&+"#%$#""(''#+)#+*"%%!+#&%&*&'"#%!'"$"&)#$%""*!"(*!#$%*+!)%#)$"
@r5396
GGNGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGG
+
&5!*<&F-C2)@39)&A;&A5100A5&,>08C(3D1534@@<1C$5"#3)1)A)/$F
@r5397
CGCACGTTAAAGCTCGCTCGACGCTTTNTTGNTCGTAACTTCGATTTTGGTCAATCACCNTGTTTTCCTCGC
+
65,>@!FC1$;3#6(76D"=&#B/D<G6,FD0G:$C5#011)@@&GA$2&?$G.D12#3"?:C;E'G1=+>)
@r5398
CCNNCGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTT
+
'('")*'(*&(')%!+(&+*$%)%+*)##&%"+&#!#)()%+"
@r5399
AGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGC
+
90E'5!E6'(E'3>#!";@("0&%AA!-)#0.5.!&=4+**(/3-4'G>.CG?C'%&$:C655='$&BE%HG*+6<=H5)6
@r5400
CAGAGCATTAGCGCAAGGTGATTTTTGTCCTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCAC
+
B76.>"/8H%!0''7A,;G&0>5$"=$675;&!9"B#<-+,?;E74+:AB/<.;'"31C>G@=8.9
@r5401
ATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGGTTATTAGTACTTGAAACGCTTCTTCAGAAGCNTGAAGAGCTAATCNTTCGGCGATACTATCTATGCATTAATAGACTATATCGTTNGTATAAACAGTGCAC
+
$$()%+%&((&%""#!*)&!#*!!*')*()()!+%'$#"!(*#$"+"!+&&"(#'$%%('+$(*+%(%*$&+!#))+'*%'#&*#!+")%%&+!)$"&%$*'*#')())"&$!#""'%(&#&*'"!#*%(*#&$"#*)!*")*&'(!+'!("#)#(*++%((&()&
@r5402
TTCCNTTGGTGCTACTGCTGNCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGAACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGA
+
D?#7)-'H:G)"'@'"++&0+<F(*"0&/+9C+!.>B@%(?D,G!?%!<(D>D"D3)<AGE=1H67&E#7HHFH>)>?%/4D1C*8>(2
@r5403
CTNACGTTGTGNAGTGTATGCAGTATTTTNGACAATGCGCTCGGCTTCATCCTTGACATAGATACCAGCAAATCCGAAGGCCAG
+
"#$*%)%(&%&$%(+$#%'(*()''"!%)!+&""+)#)%'*$$$&&"**(!*"*(&&+!$*%!'&)+&""!#*"#'$"$&((*"
@r5404
TATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGNGTTTTCCGATGGGTTACAAATNTCCATGAACATAAAAGATATTACTATACCCTTGATAATTCATTACTATTTACTGAGAGCAT
+
GG/.?C/'2192;"8E,?<091.-9A:(FCC,"(>9!7E'2@/-!"@+D3<$C0;60G@BF=3)G;(1A!(86'F<'#8?D=B>52B92#?*#7071)!F<G-,07E@.F0()@86E,7:;@.!EE$A.G$6-'#,H2)'#G*-B$(9$(H44E-)
@r5405
CCAATAAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCAT
+
(!%&*#+($$&!%(')$)##+##!%'&("&"(&&#&&%&&!&")$(&+"'*((*"+#'(
@r5406
GCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGNTGATAAACAACGACGGCACGAAC
+
G'53A==/H.<+7H/(7)B4C=)+7)$549'9#E4.#2B)7<&*%8@3AGEA6($')-)HC6>/D;/,
@r5407
GGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATA
+
"3;/(:61+4:!+7#D8E3?16.,*2-9C2E>:1379><;D@#9"(2A>8E-BA!/7:5F/,&?8:"7G<A,C.%*&'B1
@r5408
TTGGNNAANGCNTCNNNTNNTNANNGNTNNCGCTGANNANNGGNTANNNANNCTCGAGANNGNTNCANNTNNNAN
+
!"!$##$$#"$#"$"$!!!!$""""###$!"$#$$#""##"$$""!!!!$!"!$##!""!"#!"#""!#$#""!$
@r5409
ACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGA
+
%CDE8(0@H@7-G801DGDH!&3,DD,1#D6)@*A3@BG;77=%:D!./-2#0;1:A;.B.('87+F893&A:;;(&671"29):3360G%E(E77<*.826-@+E44:D;-7
@r5410
GTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATC
+
=G(>#>@;'):?6?65+E7-/0+(92&'1881<8EG<>)<3/5#5+.'($*$7B7-16)>6!#5&E?F=9A1E"/
@r5411
TGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTNGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGTGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGGCTGCGAT
+
8$)$66-='$>GF<#55>="+-@HF*>,E/:?02*/2<+;>0HA:<;2'=9@3;$:+1/?';EB7F7+;5&FB.47B4"'.(4%B3=56;3EE!@-*456?G?8D-52*1D:'@?:*?64/3%-)95&F$@,4;H8<:C*8#"(5+#>--5@>*E8#59%>E-!E-,?'.+;(,&(&<,2<A"@1#'+5*.D$6;-,G??=*CGGEB!,<A.2-.#"$'$5F"==@1$=84%&A/BDC;('%7F)G:D+H@:%7230=B55(C6(/%';&1=F8(2>=E(6!C7<=;&<0<+++B/4CC2C%6F61B9C::<9C@$0:4*
@r5412
ATGGTCCGTGGTTATTCACTCATTCTGAATGCCATTATGCAACCCTCACAATATAGTTAAANGCAATGTTTTTGA
+
-.".?G,)8D-9G#;@/+*&A6AF-?6*AH(H,8*+/2@42"(4B&/.F#F+;F)"/.C*E*@(G,0D73H,35C
@r5413
ATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCT
+
H/((H:;@(H/E!=(BA47?7>/%=*(>75B+F&&1%5'AD'+/#>;!!?5#>3DH197-BHD:;,BD8>+>ED!G(.=->>4D*E&4D35<AA:*H32-,-H:
@r5414
GNGNGNATTGANNAGTCGCAGATCAGCNGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACANGTTGCTGCG
+
(&)!%"#'(%*$'''')%+!''!(!')(")*+!%+*%#!++)%%')')(!$#'+)&$)""")"$()#$!!&'$')!#$$!'"!#+%%)+$"$#&!&&#*&**#!+('&""%$$'"!"#)")"'!*+%$+'*(
@r5415
GCCGAGGAAGCTGCACGACCGGCACTTGATGANGCGTTCGTTTCTGATGATTTTGCTGNCTCTTTTGAGGCCACCGCATCTNGTGCTGNAGTGGCGGCCTCTGACGCTTTCGTGGCCGC
+
%**+!&$*&+&()&")"#))+&#*)('#*(###!)**(&*&#&'##$!)$)+#&##(*%#'*&$'%!''&(+%*!%$+!+%)!#)(%#"$&'$$(#*%"(%%)+)&#!"'+!"(*'')%
@r5416
GAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGC
+
1,>57*2*!*G5B&+H9-:B=7G4:':).7*2;@7#*.A(5)3:H
@r5417
GCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATNCCGCCCGTCAGGAAGAACTGAACAAGGCA
+
)D):(!$;-*+8?!,0>F<27<698.C+*<6G&;)(00-=5*1/,4$=46?0027/$@2@:0,4H:*8E14)H&"?G4B4B-';C="+78/>9316EAF-H1B3E%?/<@++=A">@3HFF=4%
@r5418
GTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGANTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATTAAGTCAGCTTACATGGCCCAGGTGCAGCACAGCATGTGGCGGGTGACGCGAAAAANT
+
@&?/.(+HH6-#E.*(7,FE7,>+G@$C6:C9BB>49:5'3"E&A/"-33,?=&;.CCB#2"&/#/(?A!@(G+3<A3;$0';'3-/:;BA'&04'(>F=)A>5/*A:(>C:CFBE9/94+%@2<6'.AA(38DHD.(9=7:2A:@A0%
@r5419
CCGCCTTGCCCTCGTCTATGTATCCATTGGGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAA
+
84E+&#H0HB%AD-)"&=*>7-24=60&420,:GC.8&(3@D0GB,:5.&C6D36*5H37GE$A?A
@r5420
ANCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCC
+
B*!>7+8+'-.-:B$B9C,$%FD51/./?8>AH2F$2/B<<A:7?
@r5421
AACTGCTTAACTGTCAATGTAATACNAGTTGTTTGATCTTTGCCATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGCATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACNCGTTGCTCATAG
+
6E*7F:7@)1$;9DBH.6<#;H)H9:2<),H@31.92G''D9,&C;?H491FH8HDH54::C"-G)@70A/2>1(%=*1CD@6)E"4@:*!*3+0%;!03&BB40?.'FC?A2;;2)/811<&3BD<;8??8-7;F&G'/DDB=@)AD7@HH.:0=.2(6$4%FH?2
@r5422
GGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATA
+
>195:04+)0)#?8(%97(/3<@8<F+3ABE8=%!A7)"2.9A7-F9D)3G8%)3=)7=E;1>?8;+#)0,F)EB@G1%HFG;</!)/A4*GA(C,5=3;056843'E5-9/2A8;
@r5423
TCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGT
+
2<B#BD,)498=38&$65'%9?$?H5&>0E.&&:?7"%B?"@8'99H%@;/>--#-A
@r5424
NCTNACCTGATAAGCAGAATGTCATCGTTCCGGTGGTGGGCGTTGATGG
+
#*(#&$)&$+""))!%&#%+((!+$+#*'!!'((*('&'$')*%!**#&
@r5425
NNANCGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCNCGCCCTGATNAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGAT
+
'%#)+&+"!)#!$!&!"%(#"!#)%("()!%*!"%!))(*+$&#%!)+&$"(*%(&*#+!(&)+*$'"+!$'#$)#'+*((*%!**!'+()#")!&+!%&'$!!$++$&**"+$!#(&%(+$)$"&*$!!")!)%"$$'+")&('&&)'$('*+%"$)"))#*"+'#&*'+$$!!(&)"$"$&(*("$$*)(+
@r5426
CCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCT
+
,5HHC;2E':78$:.@1,#?GB#-51:@1A(EB1>4F"D47
@r5427
TAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATC
+
3F/B+?A*60:@>D@7;5;E%/58#!7$2EEF((,8&2'C)97,CD4H<."(#?5D84C4$)CH(@)F<'4,0&$1,6.*
@r5428
GCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATA
+
1D<@#68);!?&3EFF+;A7F>-A$A*,"(G-4#F+'(;&@DC%F
@r5429
AATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTAAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTATATACCAACGATATAGTCTATTAATGCATATATAGTAT
+
8?+=:<3'C"'@HB##66)3;B$&)!6B!&E=1#>$=/B8&FC@E=G8G7>1@,+3(?'7?1%C82>/C'-<,&5G:>252(/2EA+<*<5?")G$3)"22-B$:24=0%B?422,7C$G:+A?0%&,/::4H'+,(.>+,+*=-DH%;HGA8%04%F:DG0B:;'4.A:"23#=21!'DC-@(7C<AF$617@1!,C@-.+0C,3)!>:$+$-E6BH4E92B@
@r5430
ATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCANCGGAANTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAAT
+
1%GG?!$<+E41F?95?),="G:,>?4-F<#.G6C"2!A:H2:#BF%D)!*<+2<=-+H3@.H#,7!#F@2!-/48))C3?%+/.'3;?E/4BF$=HC#%-))1@/H&$E6G",$,<'#&0"B*D-#;D4D1;=*,D;#,50/25(4')'
@r5431
NTGCCGTTTATGCGGTACAGNTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGG
+
&'07/,+H/=1.4,1+%8$>C<HC4-<1A$H6C-"H-.(H5*+H!*2'*:H=-.9<?AHB>*E!D>
@r5432
TGTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCCCCAATA
+
&!?7-<2)C'7%8#3D*D/8+G,@/1,7:0+@.($)!2-1?'2>C82=
@r5433
GGGTCGACAGANTCCATGCCGACACGTTCAGCCAGCTTCCNAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTG
+
+&(*$%"*%*$!#'$)')%'"+!)%+)$'#**("'+**+'$()(&%+&!#&+!#*+**&"%!!+##!'$""#)'!!#'%#+#'%)')(+))##%&''&!(!)%#&!!'%#$#''#!*#%"%"&"$(!()%*&$+%&)+&)$
@r5434
AGTGCGATCAGTAATTCANAACCTTACAGAAGAGCAATCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCNCCGATGGAATGGAAAGCATATA
+
)')+!$*'()"$(%*&!!""(%*$&!#)(&)"#%%(')#$+#"++"(+*#(!)!%#"')&'+!$+!!"**)"&"&!$+$*'$%+"(*''#&#%#%%#('$%&"*"'!)!%(+!+("()!)!)*!"+%'%"%$"&+)&!$))'*!$')$(+"%($++*!##$#'%$%)(+(+!
@r5435
ACNNNNANGNNCNNNNNCGNATNNCNTGNNATNNATTNGNCNNCCNNANACATNNNNNNNCT
+
$!"!#"!!#"!$$$!"$$$!#"#""#$$"$#$"!!$!!#!""#"$$$$!$##!!"##!""$"
@r5436
GACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGC
+
GC6*020=#?07'@2+63+#>+91%$A&.8<>)0'-G'H0-9BCH7)>
@r5437
GGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAATTCAGCCATGAACGCTTATTACATTCAGGATCGTCNTGAGGCTCAGAGCTGG
+
+#""%&)%*!%'$++%$$'!"$)+#'$#""+"&%*!$!'#%(*%&!&#'$$+***(+()'(&$'(!*"$&+#%$##)*&"!((&%+&!$&$
@r5438
CATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAG
+
;;?=4C7EHA1#@:?713=*<55&;-@<!9>?5?"-5('HEC2.481..,?B&?/%@,7&)97?#/#:#;FB'")(?2C(D$<B8/)6(;B)"=?(;..*0;A87&G9AFF24'=D**-(8'$&.)&C*5"(4"G,?FB&
@r5439
GACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTT
+
<<G&#,D=.A+-(#C;+6&*:F<A0#*FH%$4C<8=DC.8+)-
@r5440
AGAGNATCAACGANGNCGAGAGGAGCAGAANCAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAAC
+
%)$*!)##'***&#'!%+#"&)*'$($")%#$!""$#"""$%)'!&"'!'&!*'*'!"(!'*%%)"*"*$(*+!!##$($!*"(+!)+*%(+
@r5441
CGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGT
+
D5+,5!;!&%4HC@#6;6/"E#./,(54+9:7A+&(E;@54::.1:&"A.),&8:
@r5442
NCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACANAC
+
!-$C.EC@.9,+"9>>H#$)(9H3,7#)8AG*B7<),25:4!E8!EG!8D*8530B"$9@C/,A33)-%-"=3!33-%,+@#F!*F#H8$+C<<83'448:H1>2&E$,/D4,F*;C41/=6;9'!$1>'/<<
@r5443
CAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGA
+
@5C4E/"!B$5E"590B>#'"B/)>!35="F2:;8@!>%0=()*B"@?,="*
@r5444
TTTGGGATTCTTNACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCNTTCAAAATTGTTGTTTTACCACA
+
<A=A)()$6;-804@8+5+$&E5C>'5B*,4:;6/7$,(.&##0/F':@,)"D$%-8*2-.3%A&C5G">13%3B618>?#'?<53)218G**+!;/G,&"!$3;+F06/
@r5445
TTNNTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGGCAGTGCAGAACGNGCCGCCGACGTATGNAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTNCCATACCGTA
+
)(&%-+F<<E8"G>)E;7F!F&A7%;;')9FEE,AAG0).EB87#!?E$1A-!@75.G>?#=98$36.)3/,%H>DCE*B(8G/791E"9183"#2B!EDBG=E03,>2G3(86!3#)F7;?B9E-'7<?F0(=D$A"!)1!8"/9+9D:%D:9$?,B6("3C5-)3<*'G;DF99!4?'+=.)4.(2$#F0+421*.0")79)<!2#.*!,)+E3,2&"6G6CC:5F,(D?AD-&D1#?7E03)8H)-?34D7:B,)B0<++43E9@
@r5446
GCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACANTGTCATCATATGCAGAAACCATGATTGCAATCCTGATTGCTGCCTTGACNTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAG
+
<--D-/F++%A6,82,2G-6!4>2>')(EGD;-F!0E4+%"0>(:E32$#2$A(0D4*#0*+@3@B9-%:C#12.?9@6#,%18BB1?+!DE5-/BF:CD(;H#&B*C19>AA0*0D*3=@8H>:3!F)F;D47?A$<84.(&/9,!2%.,D2(.CC"&.$:1)C(9
@r5447
GACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACNAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGT
+
7%29'G3+@26D#<(0G6=>%7"C',$:,7)F(:/$$5%74CB8'/!;D+G>*F-4/4.@@*C&0/&#%
@r5448
CTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCC
+
;CC1@+&G76>94$;.G12#)(6.D+B$E73BFB?&HB%-(:/(21/5#9:6),G&$2C>91&GH'>=?5':-G-/(4!+0?8&#7@@%1.A'
@r5449
GAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGA
+
'+'%+#&(!&(*')!#')&(%+#&&())(")+!!!'$%"&$$)$"*(&'##$$("%'&#$")+#!!*%&%%"&$)+!&$(
@r5450
ATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATCCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACC
+
,8?*5(2F8+%3D7"97-3*&25/,4%'@;/D&+.CAA08"+(57:8;B@$>.4?C;7>8)7!"C0G4!014/B@.!?D.+7$0E-:#H72GCA0*8:A7<*3-/45C.92"*;;GF,?(*8%,6B
@r5451
GNATNAAAANGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGNTTTTGCATAAAAAACAGACTACATAATACTGTAAAAC
+
&"('!(*&*)((#+'#+&$+)#%*%""*"##+%#!#*")%#+("$)&%**#+%$%)#()"$%$+&"%*#*##)($+")"*#+!$*+%$&+"#'&*+
@r5452
CGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATG
+
:4A3H2>?4,3"H*,.76*:4>CH4*0:A34::$$C91'5;)C6&>HCF$D((%0!C(A<DFH3B*90,E3
@r5453
TACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAAN
+
1>976:@'792$@!(3#0'$9/B&+81!CF=HH&E?)%3.2D=8A<
@r5454
GCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGAGAAAGTCAGTGGGACGTCCGTCGATGACAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGGCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACG
+
B%&&FF$;44H:C,AC<<5+4=A>GDB0H3#D;;&'?20G*$=*"9"FA1=;/*4=1>1>*&47+?2)=:.?)B/#1$,H1A?:#1E(9A$B%6('"96?D1(H1A!?0$(%DBA@*/&<;-F/A?-+C<!/><C.*HB669;C?D-!-"G5."1H?5;>8.#2<=&2..C
@r5455
GCTGCATTCAGGATGCGGACGCACAGCGCGAAGACATTAAC
+
+/HF$=G,#DC.H3ED./%F"43/2CA$6+=FH/A8%#<H/
@r5456
CGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTT
+
.E.#7&'-A"B84D3*',/?(8!,=C5!&B:0439(!9).8)%256&$;0.3&,A<C$3)'/6C(:-+),557++2,%(#30>/"G*&6760=DC.1G!523)5'H72'$?.A%0G&2:2C$;"=
@r5457
TCCTGAATTTTCGGTGATGNCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGNAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTAC
+
@#/,*2EF5B1-'?4;"F.-%>E06@C/%8%FE%H1$!'",.@&-,:;7F4.=*#H@;6?1C.<=&!-:<926"1EB;@),-C/7E2,B+%6)6$
@r5458
CCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCNAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGC
+
32,0$<&$)FA@'?%,"8!,:A?3=<*HH##')5>F85>D2$(>(22)4/@#?B3"B.>E%,8=#.!&67>71).78A/A!:3(+&(F4(4!C#4/>"?3*7*"F+4&;85/G)11099%B,G&11E97;2(,C!+5/;,;/45-?<!$>D>"%+7'(E+A.-3;.$9#2=1()
@r5459
GAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTNTGGTAAAACAACAATTNTGAATGGAATGATTGGTGCAATCACC
+
)6/E9HA#C(%!-+CG=%,#0'*/7:+:B&8E(=522+641D%$#@F>8;B6?$9)*C%CH+.299#GBDE?*.2,D/52&;C4;9C/,1:$B%-,/;:2F'>@5B7(;@>+E4.020C@5>-#)&?5B-(*086*,+H$C<>)>%
@r5460
TGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACG
+
3-'>A/'-H4A!=#*0B6B>C75-(@5/-=+05AB3)&18-=.G3?87G93.2$D!G&0#0'7*>0&
@r5461
TTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACC
+
C*#F3,F.?F><3=?A*-E@'GC%H9=638(A*)5'/(/&1#?<)BC@,E@@,5%9</H3D3./%9.4?
@r5462
NAAACACAAGCCTCTGACAGCGNGAATCAACAGTGATAATTCCGTNACGTTACATTCATGGCTTGATCGCTACGAAAAAATCC
+
#6B.CGC5,B,8;$.6+,@D&?<)F5"-5H(EHE=)B.A<=CG!#D=H+@.6<1.?@0=A$G1;<>96".=E&??H624<CEB
@r5463
GTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCNTGGATAACGGGGCGCACTTTTACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGNTGCAG
+
FA$78#-"4#!!H/4<42.&8=6%+76%>$/#.>++:E<$%$2H;)3!@:79,4'C.*)+#2(-D%0E:%A.9&9<*.>#;;E*G,>4BB'C#?0/$?HH!32F,GE@43@FF@B$FE
@r5464
TNGANNTNGANANAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAG
+
$&(&%"*$()$+"%*#")+!+"$)+#)#(#+&+(&+(%#+!%%)&+%"*#)+*%+
@r5465
TNTGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATNTTTCGTGAAGCCGTCGACGCTTATAAAAAATNGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAAT
+
!$G>(H$4&61614:6+G70$<":/&C3C29=/8&HA$>0FF'$7D8D=/!.:C.*A3$GGD'10<&:,$=GD!@#(6#G6DF9+1C2<'7CD+CE>74C7)1$C>3B9,+,"CAC="&'*%8@$+:-445@+8$C=H>/2=#)7CD:4)C)
@r5466
CGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAANGTGTTAGCAGAGCCAAGNCACAACTCTAATTTTAAAACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTT
+
DDA'6$-.-6DA0>.*8*,/4FBBF#:&(3!DC%G-3?%$1!+E3(:&#G(1D688;!F+GF$#+#='+(;)*?F%;7/!<E;>0!.(A)+H$+B3-0D;C1-50'@.:G5GA?CE$'/D1"@1!!'&2>-/*:#36CA%09H/03H%$D,H;<;+;=02@@B;,=,B872*F3;9..23*BG=/(-').*:+187@71
@r5467
AAAGTGAGAGGCACCTNTCAGATTGAGCGTGCAGCCAGTGAANCCCCGCATTTTATGCGNTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAANGAGANGCCG
+
2:F!BCBF..*C4'HG6E=</+@@E=C+?4#?AD%&*F"+$F?&C=$?5&!H3!GA-F/5;%)1374D)54>/-3C80!&0"5BD63%;=G66EA<)4!%G?-0;""5+F4(.AB.B0/7@0"(22
@r5468
TGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAAC
+
9*B/C#E:A&A<;.>76A$&GA&1A./F1"(7?$F<6.";2)FDHA&&E!9!!2@E4&4&":4E<7>AC9
@r5469
CNGCCAGCCGGAGGGCGTANCCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCNCCGTGANCG
+
&#(*%&((++*'('%!!(#%&+(+($#&(('"$())('&%)*+)))#'"$)*%)+'$())+)#"+!)%$#$!%+'"*)*!"%$(((&!'"%&$&(%'+$!$
@r5470
CAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACANAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTNCTTATACGCAGCCTCT
+
29"9%A,53/?)".FE!;.<?0#38$454'BG0'=':,18;<+2A3B8.H$%2D>E2<4D$),(E<8'833AH?#;<4*/ABE.$;-0HAC6/G"%G?H$1>@13*?3CC39#
@r5471
NCTNGANTNGGNAGNGTGCCGGTCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTNCTGCAACGCCAAAGGCGGT
+
%$%!'&"!!"%!$(##$&%$&$"$$+"*$"%%!&('$!&%%(+$%+(&(%*!'')'$(#'!(#$%)'')&!!)''+*
@r5472
ATTCCGGNGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTCTG
+
$$+#$((%+#"+'#&&(")"!*%!#!'"+'&(#)!$""&#)!"!*'"'+''%!##'*%+'+)#++'**&+('!#!$"#$$*#
@r5473
TGAGCGAGGAGCGGAAGTTAACACTGATGAAAAATGGCTACGAAG
+
/D9*:&?;<1<;)4D=?$B03C';61:3D##(8;D8+)22,4?0C
@r5474
GTNCTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTAGATATGCTGGCGTGGTCGGAGG
+
5?&'(CD-H9+)G-B<B!>#0DE&6H.0)%0"***EG""/D74%)70B%1=7@>E=E=H%=,#8)/*99?BG0.(%+@(<:-9+<=?9C0/8<4CA;?/#0A?#?)&19.F!@F"/A;
@r5475
NNNNNNGNTANCGGANNGCCNANNTNCNNANNATNTACNGGCAGANNNNNNNCTGNN
+
#!$"#""$!$##$#"#""$#"$"!"#"!#$!"#$$"$#$"$$!$"$!$#"!$"$""!
@r5476
ATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCAC
+
<AA!<H738&@:44A+<332=+/$4D3>F;28,>#DF%8#D2
@r5477
NTNTCGTNGTGGGACCCANTGNGATCCAGTTTGTTNATCCGGTTCGTTTAGCNTCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTNCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACG
+
*'"&"#)&)#*)$$"#*&&#!"!#+$$*"*%'"+!*!)*($&%$!#*%&#(+#)%($$)+*'+('&%*)'&&!('*&%!'"$!''(*$'$#&(+")'+#"+)!%('!!%##!"&)%"%"*&+(#)!%#%!)!#(!+'$&#(*"%$"(""')"!("$)#"%$'##$($&&!%&"!*&*%)!%%$"(((##(&&%((!!)+'!")+'%")%#"%%"*#"+!!#*(#&+#'#$*!&)+#+#%+$*&$)*+!'"*"'!$!'!''$%%'+#$$$%'
@r5478
CAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGA
+
784.>*"/$=497<42,B3%8/492*,&3ADBG;.+"&.02A$!1G;.2-%90/0@C,A4-%0@:8338";8A7@=C??E86?*F6AH+E3A/44A
@r5479
TAGTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACACTTTTCCAATAATTGGGGAA
+
6A;16C1()(#!-?4;F2)79&8=<'!H<))37,.38B6;1*+;-)+B65)<3:,!93E&3,G7888-E,*8&FB&
@r5480
GAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCNAGTTCCCGCGAAGCTGGTCTTCNGCCGCCCAGGTCTTTTTCTGCTCTGA
+
/>?)D$:&.4"&9>E1*3+HGH<F(-DF+H$@;69'=15<#5##B>?7=7=D0#6:6E;&?>'8$06F)!5A*D#H"&'E.G0#;=,#EA1('2"%E!:2FG#AGC16)1A:98:D)'?')=@--4&)'D4<88D%+3#"':1(-6:4;H;E=C/G$"*?,C.435H4@!E;D6!36/!0$<*%!9,0=-@@33/@F+.+D;E!
@r5481
GCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCANGCTCTCATAGTGAAACGTATCCTCCCCGGNCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCANGTTAATCCCTTTCCGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCNGTT
+
,%%.E-.8D/?7/0%011C'D%$%;C6#C"?%)/+)21C,6%7(7:A245E"!F9/$"9@&.17AA<3.0&:G+C70CA@;>4B#?4!:>$%>$=%?),!"'.&6=57'3H9B"93&H@=#!E&#196A5@:"=@3-(F.%7!3*);+27$??(/#C:H;'.7!075<#%#C/6@#!&A)$HG1;E!'&0)B,CE.GC%F$1(1G.G"<B/%";'9$02-(<"9.26!H@""7>#,&#40*71"..3%5.<3.:85D>:
@r5482
GCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATC
+
3*E/8;0&5#%?1!64%$7-0%;?8*E6D7:'.(<$F.H-8@!=9(F(.38"51'2FCD,B/1!CE#EFD/G..!@6&1G8?&+1>%ADE.<-11CE<G)E:#B2:$D4
@r5483
TANANTGNGNCANANACNACCCNNNTTTCATNNTNCANNGCAAGAAAATTAGATTNATNNAATTACAAATGAAAGTATGTTAAACANTGGTAGAAAAAAGTTA
+
&)&)""(!'!')!*!!'&($$)!#!(%'%#*##(%**$%&%#*'#'%))#(!'$%&)!$"!"(+"$#&!)##(%!#'(("(($(%%")'"'+#)+!!'*+$)#
@r5484
GCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTNAAAATCCCGATGGCGGTGCCGATGACC
+
"21;C6@:6$ED5.+E">#A7*?F<E;=E<#!789*)$5#.$!0??.;!B;78=?=E==*:@0%.'@>3$#624$,4$:GF<ED6?/?">+8>H@7E&C7)?$>%4=%048"?,4+:874@0=">7.5H87+*++"=EG=9.3F413>#5&B."8&$;9+!*$69FH7;C$C'4169:<61C7-,1C$G1<9DG9%CB$E#0A:F#C:?)!/H.'
@r5485
ATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGTTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACA
+
;;H+9!-4,8DF=+FDF)C#+-@?@0B83-ADC3FF)56!'4:.%9!D96?(()B/6,H3(601A0F*&+<AA%",.CD@2"'
@r5486
GTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCT
+
B/+,E.&3,#94;,(&57F52?@'3?7B!&81%+?*14@@GB$21.2;15*=H?$"=D<"#7FA+6"?#"010&8%;.8',:>07':
@r5487
CCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCAC
+
2BH/G((-0#-,5H;@8BG1.)&;=:2)E@4)F+"3C$%E</3C/"?1@B:;;A*4$2$#<7$)<!/0H(8?%&)E6!;)EEH#3DD$27&78@6
@r5488
CTNACGTAATATCCCAGCGCCGCACCGCTGTCATTTATCTGCACACCGGC
+
)##(+++!#)"*!)%!%+$&#'")%&$#(%!"%$'&%($#($'(+&!&!%
@r5489
CGCNGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTT
+
0)9&H0>4BF((95%041?,,-;=!<+1G(CE00,F4+'(5A,#&HF183@#B2+H@
@r5490
TGCAGCGGCGTTTTCCGGAACTGGAAAACCGANATGTTGATTTCCTGAAACGGG
+
==!8$7(766*-(-"--A7.F+<(%+)/?75(%(H"C.H<1&G=.?!BE(DF5"
@r5491
GNGGCNGCCNCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTNTTTCCGCTTCAGTGGCCT
+
%&(%**%()+#!$!#!$%"##"%""&#$!)#+('(")$%+&#%++$(()'#&!&"+"*""&(&)'*!&&("(!*$%)#))+$"(%(#"&$))"(%'&%&'!+$%&'!#+'%!"((%*$&(!&'#((!!&&&*%(#(%##)%&'$$'%)*&)*)&)+)&$)(%&"'$
@r5492
NTTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGNTCATCGNATAAANCTAATGACTTTTCGCCAACGACAT
+
#$+HF#')'1:B:&1?>4!*#9$=<)G&8..01&#29*15/>B#HH+37-*/$D!$06)-+@70,-)/1*4D<6'6H=+!#=*<DF668"DH$=;H>#,9
@r5493
GGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTAAGGCTGCATTCAGG
+
@;D543(20G?+2/G3FAH%=1-6)1)136*B?$6>5FC,9C3$>(-!@'6B$F;4D1A*#=88-FH$+:(07;)=.95+6"A+;)=A6<
@r5494
CGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCT
+
#<$3'=F.2!);?6DB.=C09534)&"!H<E%""E$"2G*3G)$:+E,;-)&&4>65H459'54G-;9.D,7)/E20>EEC6A559(%8A)F?,;0:&A##&3=>;>
@r5495
CCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCA
+
;B0+5)6).=4$6%67;(=78C4F;823D:6.+C-+27A0D0*F<?8!>+H;0$6615>AG/#:/F#*'A9:?"+'*D1&7HH'#3;9D+!-9=,G49E!.6=%9%;&!?"D7
@r5496
CTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTNTCGT
+
A$+C<$"$-1&.3-,?@1;A>">F1/#2"!!62:>F:)2)?4-'F2F@.;+,&4!=:<F@96>H09!<9GH5=A6$C1%CDG'&"0':.>)97522&EB:C9G/)'D*%A<,6%D"
@r5497
GAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCG
+
2.F<!-'E8$.G:=1%FD:=?<FF=:4A71-6E%G)#=3/4$6BD32'?-G"62@FC?'++">'((.)5=0"C&.?B*)+<@@.-D:6(+:/:.*.(F7">.F"C-=1/HD6
@r5498
TTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGC
+
.4)C,"0?7#EG"3317(!=F+?C;8A722/:4F=3A,DF4(+A'/F<5E"A3D@82=
@r5499
CACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATCTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATNGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAAC
+
2+,<-)69*#4*49;2"?5@G7?G)D.9FDB7?$!2AG()9/243*7$C*.=,H;EF%F$B(1E(?703<,*(@D'"=*6-22/C163.@G?/F*EG>D+!0E(,<&;60.>@$:#;H0@+,#:E++H%AAH:A=3=E,<+G9G.?;%86?F%"0#34,%$.>.33</,BE<!49*)*4D(7F.)27'F54$++>&?@H@+FC>CG';(E>D%)(+05/>;3,H-54C/EF!G'4/F/>B59D5'.!9E>A;47#;=#>$G7)(4=!>7';'?;2?-C*8D2:8#$&B+*0&;/0A6D)D/+"%(&B45@!>A17&F=7!)E,7)0-E)D++;359G3.>%@HB;#>73?.&CE5!>*&*'%#+D'D.$+?>*4$$)EH<>%-EA&4>!*'+4-1
@r5500
TCAGAAGGCGGCGTCCACAGAAAGGATTTCCAGNCCCCGTGCTCTTCCAGAAAC
+
5-/@G4(03%%2;!5H(=?=$(=B74!"(20+*162%47BG"'8..,*FE&#>9
@r5501
NGNGTTCGGGNCTTNNCTCNANNCTNATNNNNNNTNGANNNNGNNNGTNNAATNNANNTGNGNNNNNTCGTCNATCNCNNGNNTCNNNNNNANANTNTGCGTGANATTCANCNCNNCTTNCNCNNNNGCNGCACTGTNCTNTTNNNNGGNCGTNNNGCNNC
+
"!!"$###"#"#!$$!#""$"#!#"#!$!#"!#!!$$$"!!##!#!$"#"#"$$#$!!#"$$$#!#!!$!$$!$"$#!!!$$$#""####"!!!$$"!"$!""#!$""##!!"##!$$$#$"$#$"!#"#$$$""$""!$!#$#$!#$$#"$$"!$$$"!"
@r5502
CCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGTACGATGCCATTCTGCTTATCAGGAAAGGC
+
E,7@E5@"0'::4/=,FG4F&&7!*>&,82(E8-=C$83.+E88?0588B016<D1;+,"<('8=;>5@,FA4:4H7<@-D6.@F(11A05!,#
@r5503
ACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAAAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGNATTGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTA
+
0-G7=?-BA0F1<)%EC%<)&/54.'#./:>G7B1:.72:=AB%<(@%44<24$-$#98+.?>=%+;#?''C#,?0E(0A7*7;<,&>80@#G)8@,34!4><0/>()7=:-6DD!1;";*D8>,8-D?H-=!D,?!.D0@2H0'?:C'8E;::8!871,1..,,.,"%'.=B/)F(9;4'CF*#"%.(%%7>@"BB960#>-=</('#"G72-18.BH*?B%
@r5504
CCGGTTTGATANTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACG
+
6H6/4$/56HG@,2566D=-H>=5!$5A1*"0)7B"4;9!@8!.<'6!F:H!"#%
@r5505
GCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCCGCGTNTCATATTNCACTGCCGTACCCAGCACCNTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATNCCCCTCAGTGTCCAGCACCGGCGNACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACATTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTG
+
E$-C55GG"'(A.6@E=,F7)6+14(@1*7<?D#=+#!G=;5G;+16,B'9-?6#.3A4G)=>8%-)+):>4-4GDE&(9#?/(-A>>"D(>&EFF*%<HA02#'5D8",+5<:73>59H@B8!"+#"*>''9-.613A.D4$49>&1&$%/9'2,H=2*!#B.58D$+$&2>?&:3""'>).0@$0<4#?#E2;<:B!'97$?50=4"/'25H'(?'"0/D&72@)@2B>C57B>9!%;(#%5:<9#%A:-AA%E)7!H?*$#1..%F/&=&6
@r5506
CCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTACTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAAC
+
B-6*7!?G,97)"6.5'C#D47?$3%&G(;"@D<.9880&450<,CGA*?"$D(-7$7/'%$5/;2;.;-#,;>55GE9&!H5E!!$7
@r5507
TNGTTANAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATNGCNATGACGCATCCTCACGATAATATCCGGGTAGGCGCAAT
+
(%*&$*#+)"(*##(+&!!!%*!+#)+'*&&&)&%)++'%)+$+'+(##*!((""+%*&)(#!#+#!"%$*+!!''+$&'+""(((#$%+)'%+"(
@r5508
GNACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTT
+
H+D%D'F!.,8.8)!8!6F=FH;G;+;'E+>/<30C'6&-1<,#47E8H7!47H(1*.=D11&4.
@r5509
GCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGG
+
>*-?3-A+#!7(A60,C7++CE1//#<CG'+@C-"328"64<"=C:B
@r5510
TTATANACCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTT
+
)%"**##+)$$)!%#)"#%'("$#!+'")&&'!#(#*'')*(&&#$$$+($')$)'#*%!""!"(!&#*'$#&)$"!&$)*!"%&'&**#*"%!##'+)&#$+*'!*##()'+"*(''
@r5511
TAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCAGTCGGAAGTCCGCCTGCTGGTTCAGATACANCGTAACGGTGGCTGGGTGACNGAAAAAGACANCACCATTAAGGGCAAAACCACCTCGCNGTATCTGGCCTCGNT
+
,6@%35;'-(<%&?EAH/#;8A.)0?64/G4H%>A)"B9>"6#-><&A89%>7;;4,>(A$*87#!EC47>:114A.74E<4>2"#E:7!F79+)8;D-"05:.&A#625'<-?5"1'CF5B$)0<%D36)0A>2,27:A$3<($/(?("A9:"+$+%?<D"##G/&=H0FG2:7+/4@$'';$0$+)-(?#D@8%-;3D8)
@r5512
ATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTG
+
-7-=.1&*<)BC?@&(@?1$E"=3>/D44+"C339+9+C4><:GA7G+8G'?GA5*.,<=$,H5/;?4)++6-0(,H$D'8)/6(A4(@"<A'1E/=6.B3(6@!D=(B"+0
@r5513
CAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGNCTAAGACG
+
AF-H%)C)3H1''&"6!7"-6#0;=F)'D29$=(71D7.@$D4:'.#E1(#0@B$?G&+D9.3/!1G".'D$1:HC+>FF4;(55("E=E17C1/E<=,*+/.DHDFD+G+!F9(@.@D6H8$2'C+5HD53D"$E1)61#0!C*"@5:5A:F?./'9)#34A=5*,5-4CC#8(96,
@r5514
TNNTGNNTTGTTGGGCTTGTTTAATCCAGTNACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCT
+
$##"%!"+)*!"##(*($""''$!)%%)("'+$(%('$$*"&##"&'(%$""+$#"'!##*('##&%%"$#+$'""&"!()&)#
@r5515
CCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTATCGCCGAATGATGGCGGA
+
=A0/(6!"<G/CH.AH*<A$)'$7B#%D6>)>GCD>1,D'=0>E3B+@+G&!@
@r5516
GTTAGCAATATTTAATAGCTTGAAATAACGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTNA
+
>AB?E*"&B@:+;0#-D*1G%'?60,2##&91069><:D(G1F&7?G:G3'.G-:!<F8-(=<8<<38)/F)BG1%9?&+>34>*-6<F/
@r5517
NTTTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCAC
+
')$)+%'*#)"#"+*))"+)***$*)'$$+*$!')%%+&%#
@r5518
GATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACA
+
:H3;CG.&<FA:'F@524D&$,HDE%F='2@+.!"GA83E.21;%978)G';0H87D?&7%3?
@r5519
CGCATTTCCCCGTACAGAACAGTCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCNTTCGGTGCCAGCATCTGCGNCACACCACCGAGCACCATACTGGCACCGAGAG
+
=$!%9$2:./1<&;/G=+D9*(@ED!4H=$"@=<@(?8E&0,&?$:$)/D@8A3$A,=2+,,9?7<EH#4&F)=(G>=G$0?D(,CDC(('*#'>F>:2$#=5&3B4<-+4#9!H-%D%!1<$2F52%)2G;<,"<F(D><0&-?(=;.2(#0.&"5,E4@A'1("7")
@r5520
AAGTCCTTTNATTAACACGGTGTTATCGTTTTCTNACACGATGTGAATATTANCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTG
+
+!('&!%*)%%"#*'++"!%*$+$(#'#!"""$&##!$'#(%#'"'$&!())&*%(&#+#'$)&"$%)'%(!#!+')+*(+%$"!#*+&*
@r5521
TTTTATGTCACGCACACGGGCGATGATGTCAGCGCGGTCAAATGCCCCCGCCACCATCCCGCCGGGC
+
5G=6B<:39A?;#9H)H6D:G#BGC/;0<G+#8+3D,A9%-&>1%0@D+7'?*##C6DE1,4B$,G2
@r5522
TAGGTNAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTNTTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCN
+
$@%'E4;(-"@=#?(@-=0=>F/26C4;DCFFG5E#%1D,3E&G#)<2,,*@&#':5?(-9=EA0(542269821%3-@AH2'71);D/6E8=G$CD#%3.#HF+E#=@-1!"D)->,!=<64/F?D5A<0"/?7B+
@r5523
AAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCT
+
C,H9=&,!/H9$F!!16HEE4ACFD<6)A@1=F-C:,.&780(%?CDF,E3<!47&1)C
@r5524
AATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACA
+
=(DF@;?,$5-;BH/H521=7A.AA*+9B-5D)A%.0;0>AE34-CHF:-F=G=*'
@r5525
CAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGT
+
7:,E<,!=2*<8$+0H06%3=???+H:.G;:,)A9#!D)86"",1@!02,(
@r5526
GGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGC
+
>$H)B=E3G+=7$'?20$:E?A('&$!@<)6)E/(B#D27.5C1#%31'HC"",C,#'0:F-
@r5527
AGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTT
+
C<>(8)#$$8"+;<:803(<7(*&=+/&*"(+*"B@007D#7#891/;%6=98,B-><C-ED'6.C:=."DH@647A>CGDG>F;<;<4B2+D(4)>=/$E91?D;0BF<%4#8G1"'@=:,C/G9&%&('@#!46(@=&551?G8.3D;D74!>E/D
@r5528
TNGGAAGGACCCNTNACTATGTAAACACCAGGCATGATTCTGTNCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCNCACCTGCCTTTTAAAACATTCCAATATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTAGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGC
+
!)%!&$(*&!#'&'&"%+)#%"$!'*+''(!*!(++'#'!(()+"&$%&*''#(&)+$&+"%*%+"##*('++"!"%(%%&')&#%#%!!+!*!")%!*"!(&)((&!%'+$&%!$+"+#)&&&&)!)(&$*'&%)"#*)"%$($''#!)*%)$&(&#*))#)'+&*#&%'+%!)")$(!*%"$""'&$$()()**""!&+$#+&#!&'$#+#$''!+(#&&&%#)*)%)#"+)+!
@r5529
GACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCAGCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGT
+
=@G:;8F;2...'E.E+F(=)BCH/A3-7G*"?/=*17;G)-?!&A$'CG:&E5(4#?*FD:1.0<(,'F@8B=>C3D&1BD+6;>078"*F!*=$*#82")A8")(ADF8F3?%8,,!G
@r5530
CTNTCTGAACTGTNAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGA
+
%%$&+")$*(%"$("&!("#%+$&)"+)$&')(&(#+)#(#'&)*""+"
@r5531
TCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGNCGACAGTATCAGCCGTNTCCCATTCAGGGGAGCGGTTTTGAACTGAATTGCAAAGGCACCACTACGCGCCCCACGCTGACGGTTTCTAACCTGTACG
+
&")%$#+"+%%#$+#!&%*))+*$+!$&#(+&+(!'+%'%#"+#%$)'+!*!!)'%&%!*!+'!'%&(+))%'&%)&)&$(+%%!"+&"#%((#%'%$%%*#"*+%%')$)&&+*$!+)*'%"#+'""("*%#&!)'('#)+!"
@r5532
AAATNACGGGGCCGTGGCAGTCGCATCCCAAACGGATGATACGTCATAAAGCCATG
+
)$%(%+(!%%+#"'!*"+"$$"**(++''+$##&$+)+*'('&%+*%'#!$'+"")
@r5533
TCGGCGTTTCGGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGG
+
#%)(&#%$('%+)(!*'*'$(!+"$%)+#("''!+)&&'&")+%"$"!("""**&&(#)(&)*'$#%)()'((*
@r5534
NGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGGAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTCTCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGC
+
((-09!*$D,H2/D>AF6:0B'/0+7'"@0>9?4#6'C;>!@;,,3&#(B63G-&#!*")863+F:<-8%'49B6@9C"3C7%:<?5'*;<1%7+@%"&/">.8'3-173(BG9/1=0727*?#+6H;%F7;BG,GB$8.DDG=E-4?1=G*';G3#;3&(F%5:%4/9E?=E#(*4AH$&3>:H&C*8>$
@r5535
NGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGNCAAATTTACCCAATTTTATT
+
2+.6,.95,6CB(:#=GEGE"D9G1)8@+EB';6F-'@@B!C+FF2$;29'8H&E$+:E6/?&2:5B07A$H6<==12%=-C>.?;+:00E6(E0.1/E#F<3%D-B.$%?H8=C208.G@D4=-%%8&5
@r5536
GAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAANTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATNCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGANCTCTANATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTG
+
0(#*"G/87,+H8-$9=)5HB7>*/&50-!;"5&>1'1'>4/?0+-BC=6CCE')FC."00A,$.*!#H/,;G9.,;",5?@&13AC*465@3+H8/7<#?G'G6-(#-2FA6#9&!@$?4"FG;A588++2B,$:?=H&1-4<CD(406.:?36,/E2:<!04"41-!)"*2-2?F8&DA5(<773-5!?843&6&%#E4FC67,8E%*54)+$62=?<=8&AA@."3/)F#/7B&?10)9$5&A1#79=$8GA<F%>#D8-B5%+C==(9>6&*#3&(,10=%(E4%"$(G:'1'=>7%+'621A>'CF9H*3='C<6B()E"72$+A".'E36>$(+50D$#
@r5537
TTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCT
+
0&&%52,,=A-)EA='-9-$=CG)*<;4&,;?;&5E)G197/9'$B)(9#3(+,78.#72E.#H+/HF+;&5;;H80"2#:!43$6FC)8
@r5538
GTNTGNTNAGCATTCACCGCACCGATAGATAACATCGCATTATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGC
+
#*)&"'&!"$(+!()%)(''*)%+!$*((&)")$!+)+'"#$!+#)"*)()*%!+!+$('!'"')%*+&'(!%+&%("#'++*(%!(")*$#&#$(+$'#(!#*))'(%"&&)#&#!#&#&&)"*"%*")"&'!"")+#("$""!$')!")$#
@r5539
GATNCAGGCCTCGCTTCCCGCAATACTCGTAAACCATNTCAACCANCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCNGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGNCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGNTGTAC
+
$*%!+*(!*#")&''!!&)!#$*+$$'+*("!$&")%"%$($("+")($*)##'&&#&+)+##*(%(+*())(+$+*#''$*&$&'"!%&)!'$")%)&!%!'+$(+#&)(+#$*!"')"!(+#+!)!+++$"$!!++&%!%&$(!+((&+!(!)%'"%++&*%+"$$&*'(*#!&'*%((%'##+"+$%))#)'&%(&($#!)')(+&(+!('$*'))($$$*((#'!'"")&"!(*))!!)*%!)#(!'+&!+&$+*'&+*#%!$#'+&!&+#&'"%)'()%#&!#)*"!+)*$'*'''%$!(+%$%$"*!%&(*+"!$)"#)
@r5540
CAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTNCTGGGGCAGGTCTTTTTCCATGTCGTCTGCC
+
7#'9-B@A8B,H-B-?"=?)7:#0:5%)(>F7</9(EDF?4FA=D3>G>#,D1@34=:#/:;>/D@+D;E7$$7.-+%%EG$12*935.'&:*@11,B0!(CC$%$GC21>H,(52F#7
@r5541
CCGTCCGGGCCAAAGCGGACACCTCCGGCAAGTCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTC
+
4&((&4//F1:*.92!D8F9'/A&@@F4AE'H#%7.?;!)%/#B4/,A51F2H.>,?!)%@6.E=%7+;54
@r5542
CTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTA
+
$B*AF,0/>:%.$9C"!74-7?9"D4D4/9>@0?"/3?HB6F(A,*'45'B)79-);<0(75E$<3H9GC!50?C10<G0B)E'6+70$C70F-D/B*>4B$@8**:'1:4$F=!+G&./)#+'8!89!7
@r5543
CCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGAGGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGG
+
=';+8*:?>7="1%3<6&)-1AD),8.'>:$@B4C>'#+4.12>EH!6F769A48B"(*G/D.EH0"3
@r5544
ANCANACGCNTNNCNGTGNCGTNCACNTCCCGAATAACNCGGATANTTTTGATCTGACCGAAGCGCA
+
#"$$"!)*#"(!%$%*'(%#)"##""&#)&*+#&)*$"!''+!+*&)!#*'#"!*"&&**&$(#$!)
@r5545
CATCACAGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGANCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCNGACGCCTGCGACCGGCNGTCTGCCATGCTGCCCGNTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGATAAACTCACCACGGTANACAATCCCNGCTGGCT
+
2*+63.42?G11"6$';&*!:H1+)<:1%D/2)+B1%-:":?33,$71/5(A<$!>G)A='2H'/@>G9+@B;8H>$"&B,E;#'!&-4B2*E%:B,'-8;2G<9,G%<>!":,(#)A7D";+(86B*33)E>*00,%09>6=838GA80@$F>-;<'$@?=-10H523ED9@@BEH4>A2:8H#-4>3D(B:##>#186E?9?-$/D'A1F@@72/&(-?##C0;F(GBF07:<#&&<A1%H5342-!C)=E2B)0#1<34=HDE=
@r5546
TGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCNACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGNCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGTGTGTCCATATCGAGCAGAATGCC
+
.**!C6E@.4,C0#97"G//<F9EH-/6B8%:%+A<530E2.,:''<*GD6<0'3;:A$31BE.?+$1FB(92'<09"235/A(B@*7EE(E,6;,0.$D-'.;HB3CD#03C.51A.)7C8<4,=DF495+E-E,3HF(?#&-#*:)5BG<'88..!#DH361(C;CF60BF
@r5547
CCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGNGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCNAAGACC
+
?C-'82#D5G>4<"#>HC.<%2C812;FB.AA(%'9;;0,6?)#=,*-;+"+?6F#$2/G'6=)F,F.<FB5&+C<1:2<7D&80?15;!9"BB,4@(7A7"CFD'$"8)F-5(A646G1:11B)>G;EB(2#.-C
@r5548
ATATCATGCCGTTAATAGGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGNCTGCGATTGACTCTTCTTTGTGGCATTGC
+
A#0#$'/)&;HB6*#;0*8-*&)?2@"C"=!'5=28?(+#6.71"G*':%?+;7<(8(<<$.9*G?/%?6$CE7GG3E2(,7A(*1@*99#:<5A-82>#5
@r5549
TCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCACGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGNTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCNG
+
.76AH*$,*74:H<FAG+2F%6=<5<.EH,8HCF0&8:?"&72<1&A"#'F3.>D*F04*:EE!G>.;%/EB(F;66AD4=-80>()BED,-E6HG!C2!17@2E0:(F;3DCH6/%3*$F@"B1,A%B-.$4BABG!.-4D:5F'<B1.A8;!8@2GC)537@E4.#7%.*7F)--5@%,+)71+##,'G+E*!
@r5550
CGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGC
+
/88:*:A&.;+"/$3%)299;.A6>4D8:CA2E">:%H>):6/*E:HD8+9@D;>7=-E5D,->:83,CB:=A66@,<4?2>9*"C>#(H>3#=)4(&36D)F#-1G9?)6>"&0"'"H/C!5E3/8H<6:5#4=4"!E0H"'=CAE,8&,G;?#46!1"B*)'("*-4@%D<A:=383F?B@8$>2+/"H=33;0G(-!;DF54'-$&G2;44,/3A1*)!A)=6>6+61:
@r5551
ATAAAGCAGATGGACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAG
+
EB%4C*:1!C4+8,3C(8018#D:*FE8>6>->8G04B.'>##"'&E4.&65#"+1'!@0"&(=$32;?/-,;6?81.,"707.-*H$&"H-9BC
@r5552
GAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCAT
+
B'(.52G4CGD3;=GA)1E;$3)2F;>)9</#90+FG;'@!7"9,:7.>6E7<992?2(6:#
@r5553
AAATAGGACGTTTTTATAAGATGCNTGTTTCTTGAGAATTNAACATTTACAACCNTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGNATATTATCTGTGGCTNGATAGTAAATATA
+
1>!"8<B)A-3&*H!9/0CB9"&66*E6;0(H@(D*+3&"81B/)H$)%*A(617);!+0.%@G4C";.?EA*-!*:4<5B9D8F'-5C59*!5=!=;%ED)AGH0')-3BF.'6"E,'(@*5$)FC<30C:G0
@r5554
CGTGGCTTCTGGTGCCTGGGCGGTAANGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCT
+
<=C#&G6$16.A3=?%#1*@??+<:,G>*',88B+<?@8!'646%'>=7"*?.0&"0#@@5+%8:@"2(6C&%;4CEG--28A:
@r5555
ACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCC
+
H>B&@?1HC:=*$%!;9(=<"F/6&E"71!7E:2:FEC#*G7<BE
@r5556
TTTTCCTGCCATCCACCCATTNTTCGACCTGTTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAANTATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTAT
+
*=7D1F6!#/932>:$C33B;9#98739<)6/@,*EE>8,#0$;G5>;>F-/4D.)9H;%-D+69?#&3$+1E2/1?55!3(*,A53%.6&4D&#8"BGHFE4G4.6-D(2HC;G878+>&D4#D790*$>A2'8.E2DD2<296B%
@r5557
NCTGCTGATGATCCCTCCGTGGATCTAATTCGTGTAAAAAATATGCTTAATAGCACCANTTCTATGAGTTACCCTGATNTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAANCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATAATAATATGAAGNATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGNCNCTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGT
+
!,00*FDC(*C'(-'GG#,&:=$=.0B"D***%;"18AE'FBB;367!>%3(-$E1&C?G5'<G?;!3BF)(8)-!+%@@#>0CD@D5D6C79@'.!/'+;.+3++)$+$6()15A,BA:'G80&8EA+F97+F,=@)3:#)<'G;+;"D'1E7D2<?4.8-=6H+1.1D0B%(58#+E"#47B04#H?(9D7F1>"9(D>0>3-?/?$?H3$3)39%A-9<""$1.>#>,>&8)"-'@FB%=&HE2;1AG//E=8?#&1"&D*/$#:57G5+?A4@%,3)&*8:.)-&97AEBF6>F?39BG'
@r5558
TTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGG
+
>+,%E927*'=9D-@",>C%&5%E5?-BF026*"D77!=F=<;,H>1>4%-&$E/:*.:%(E0(%;?<;!;A9?
@r5559
CAATTATGACGCAGGTATCGTATAAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAA
+
CE?DB2@E;(4*&1!.6>='E.H:D#(>$A12)H><//72E2&45@?3A,)HA>>G>.4$'(26.)
@r5560
TCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTNAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATT
+
4,<6HH6<02!)=5@/;ACE>$&6D#$A@<AE=B+?G;(967B.B$*/$C/C;:%3CCA=G$%<GD$#B+>!80*C?'.<$(%':G)9;@48A9/7<
@r5561
CACATTANCCTGAATTTTCGGTGATGCCTATTANTTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCAT
+
6</%(A8):C&0D?0/?(%;.1H$#&5"//+F>+#.3-4C@*-9A2,&C!H"B2+?3@:9<:A!/F"C?"&!H1AB@?*B2B(-%.9HGE*365%-"5B:7.%>8#0C@7F)1FH6
@r5562
TTANTCTGNNNCNNCCATGGACTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTA
+
&&*!&#)$(!"'&*"+#%&'"#'*()%"+%*#+(#")%%&"'&$%)!"#%(&(*#!(%($#)+&+$%(+$'(&*(&##$$)%'#&"!&%'$*)$!+'
@r5563
GACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTAT
+
3&9=B#,;'&3<#9D1;;C2%4+$3<+279FDFA%?,,CDG/>@@-E%?G&#'/H-GH@H!G&85!4*E+A*F-DB"-A:><(&8F/AB?H2B0F$$AF+HE(9@'95*&%>HDG%$.#5=59&<;$,,-;7,H6%@=<C(117&?!B<G(0
@r5564
ATTTCTTCAGGCTTAACCATGCATACCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGTATAGTC
+
(=1',E3CF'442./7!E'=G8:D%6",-#8!,+73%9D0D3C2E$*:;E=77H*@.A*)(7+=CF('#/H5'!E&=!%<=:F5!C,2F'82C,?=06'+D?%%G+D(
@r5565
GTGTATTTTGCATCGAGCGCAGCAACATCANGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTCCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTACCAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCG
+
$@'<'@4,E9-*D4#/ECH;*&&!7%'?B/=2D"5DH;C#9,=D>'%/::(F;?(/5#7-%3&41D4<A#5=37=A%.!3#E&9H.1!DG@<14;;+-**1%G4FCAC8)DD*=%G=D;<$2@A,7(.A-6/F?C$>D+G:80<9>0<5BD0B%4&@A-4'6780D3$<8.&7%B<>$BA
@r5566
AGAACGCGCNGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGATAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCATTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATNAGCGGCTACATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTT
+
5>,HFH13,-&0.*2/)#(02?$70%@*92)<92">$>$H82:C+67$4.=@G::)>.-.D*C9??A;#>:$A.-)F-7H,"/2H:&.C6H>"(18192C">DH:2='>6#%!54#-6G;048;):@:C&F!AA+&.%8$7*#@+>&"./E0&C.4)F816G+9-5!E"?>C:9,@
@r5567
AAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATCAATATTATCCGTCCGGATATTGAGACATT
+
7G.$'-B6=20.:C5#9FF'55E60!9%D02:"6D*+'':.;?,3<,-97D5DHED#A!(,65?$D$2&??D4&2&326='8:75-B;'&B@G@AA2</AH&9,<6?G'/2B-B$F&HE5+&G>.<G2'98($#3=A-$FBD,D)+3A2D0<"*'!@2&!2-,&2(;05.+<-B=8H&B23"18331:A+)%@++B4#'CF%2FD1"#%16?">D36@:&:
@r5568
NCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGATGGAAACACTTGANNAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCANGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGA
+
$A$GH;B*8-+$!&H..'E6*C/=/'FG.'4@>;;F"+50';7:4!",/58C3=:%1$C(>:-A@$895*F;$C7"3@,86/C%#@6CF&F)6"A;0<:D0G'2164(81'8<<!8EF=E"&%"A)$3<'%>%.$>4)0/)C@AH,<,:)';D?'B<,=*(-A1&#,?'<:77,'@DED.5$0@D#)A$$#0B77E#'!B8#&2'>08G7*C00#..*BG+)"$*D<4:')"7,
@r5569
AATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCATAACAAGTCGGCTC
+
E*"49(A<C:/#)DD?&%&8E-G$,@$"$(5#(D+/0#@1&;+":%*),-%&(+?8<+E"#4>>2!$18<.AB0:,(:4E3AG9%/=46D/(+:D,"1).+:0?B,.6
@r5570
CAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCNCGCAACCAGCTTACGGCTGG
+
,E@2)G+C@>9FF7$@#,$;H*825"91C&7=$D$(!#=/#0G.8,;"G#533B=B9+$F&@;2AB2A("F>
@r5571
CGTCTGCCTGTCATGGGCTGTTAATCATTACCNTGATAACGCCATTACCTACAA
+
A"+'17?30:97*(F5H&C,)F%!4A1-F!#3/<9%+0,/*?%%3@:,C$"#=3
@r5572
NNTGGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGAGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACGGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGC
+
!!)%)+%+$%')')'!'&*(#(%($&"&&+*#+"*$&'##"')+%$+&&##$'%*'%)+#()()&#&)+(*%(!!"$!%%+'"'$"#$*+#&('$*+!!%#+'"*(%*($!!)*!$"($'*%'))&+&&++(+&)%)($*&("(*$!%)$((("(('#**+)*%!'$&
@r5573
CGTTAGCGTTGACGAANTTAGCCCTTCAGTCGCCAGAGAAAT
+
"+%+")()#'#(($%"*%(+&$!"+#$$*&$#+$#!&"+"!+
@r5574
CTGGGCGCNAACAGTCAGGAGCAGCGGGANAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTCAATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGNAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCNCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAANGAGTCGTGGGCGTACTTTACGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCA
+
G*7D"CCG3$0#C+AE$!+@0'87)1BCA)")AC-#(4*9D&G19,G$>?0./9A,2,&;5/9-D&.34F9=+5240?.;;:G>=A(A0"DB!B:-/2)&"18@<+!%F5=3D@?'G*(('894B@1HB)?*8<9234:4"<'$0;C0:?8:#DG!(79!*9-'C@;'F"&B'G8:=A9!H7)B+@/!&0*)"'=?E*%@GG6:HA25F$HAH&G#H@F(>@'5-#>/=#E6(*A-3*"DA8..?!-'!(,;$.43#2<5<'@G<$B+D8$H1!9/+505?/<,7*'%(/(D7>%/9;?=/G:*=A&>/+<F5*D:8B:?E?H?!G:C''9:,/2$C95),=F3+H45H3@DF$/4=7;085+9,=;C.82/08A
@r5575
CACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTNGCGATTCACCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGTGGCGGCGTGTT
+
=<C,AA&;:779@25H"3$B/"'8GH=>&/.0<"949#<F3H$*"H'(,-A;6B6,&83-E'#25BA?'#),24D=+,"%7*H%/!'2',3$'.;$$/$-=@9@(,#">4#FG=4;2GH-$E'D3@*1F&6%+B!"E'H0E=?);CCH=!;++":DC)0B)-?/)9
@r5576
NCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATG
+
"B-7C.%:'D36"<9,H@<>D2-=8(GH;@<H=@"85GG&2FF&:+'DBCH0$2???&/@H>GDCEH@<F.A7?B!5:(*E4%95,"B0A:F7G&4&3.C4G70F8B5)49'
@r5577
ACGNCCTGCATCCGTGNACGAAAGAAATTTACGCCTTTCCTGATAAGCCGAATGGCATCGTTCCGGTGNTGGGCGTTGATGGCTGGTCNCGCATCATCAATGATAACCNGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACC
+
%&&"(&'!"+'&$*'*&&'"**&+&*$'#"'&()!+!$+*'+"!"())"%*'+*#!%)$((!*#(#!$&&#+%(%#(!+(*%*(($#+*!"(+%&*+*)%*&+'*$%+(#'""))$+#('&&')'&''**+&)+)!!$$($&)+*')'!*+#%+*))''!&!#+$%*(("'+!$%+$%&$*)+")'(%"#&*')$&%()$'!(##('#*'%&&(++&%&$%+&*+('%*
@r5578
TCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATNGTAAATAAAACAATT
+
8B"B2""9>E@>"H8G,5D"&A4-$,C0)/=>:2'@5*C:@4%DA3'C.4=C%!,-)21.-@+EG!8&-94E)#*6=4>-F5)?#9;61112/D<3;5H$9@C5;?B4C1##98+
@r5579
CGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACNCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCAACAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACTAGGCCATGATGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAA
+
D1-G)6$7<B&'*3?!+8!#)(1;;+9&!4#8-):(1A@E>!237*#+</:6H@8"H&(0#3C7+8B?#"--HDH16(G?2-G=>.558#)!?-<'C%8?F6*F=:FCE86G.3)*C.!$,G?):C?:.=*.H!3?CA%%C"05$2:56&6<BCC0(A=(94!*3*G(#EG;#4GF#F%=DFG>'65BG17,%1'D:CB=%$55(6/*'!-=0@B!D$!H!,5&'!+=:1$BG@2")!%H:EF,09E&%%;B;->00@4$&7>7#12*H&-G4<-5CG%/2=!847%@=>;2F9D31%3G1;@C)*%+)H6("-*@
@r5580
GTGCTGCCTGCACAGTTCNCCGACGTGGCCACGCAGCTTGNAGGC
+
$+%'!"&%+)!!(#(!"*()&*(&")*)*$+)*(#!*&*'*+))#
@r5581
CATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCNGCGAGGCAGATCTCCAGCCAGGAAC
+
:;?,60@*=)8/C!/E#"F/9C'F;"9=88<6*##-@&E-"1;5G$E*36*-:),5?&3'+E0D;D.G1/%.-(4B4CF@<+@?;$&"4<#!?*F9>-"<5(A10
@r5582
ACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCT
+
A+>35,11;D).="D2F=HB49C:@==6->)E:GC.8<'.&@11B<)*1!>4D!HFC;&46-<@*G?.7?<F!2E&E*/:5!%?+-9?D'H0"6B'5=--HEB3CC*"0?:
@r5583
GCATNAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCNTACAGAAGAGCAATCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCC
+
(2;3E9.!?9&@DD2."<&3(&+>045+1CB1G#=D1;(%,-B*$)*0(#7A9#,!G+-&':F03(%0.6##3C+6F5H#'/$$3;@!%3!&:/B&;E!$B4BE>+2!&>$8,%@F9>H%5F#
@r5584
CTGCAGCGTCCTGAAGCGGCGCAATATNCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTGTGCTTCCGTATCCTTCACCCAGG
+
7;10.-15--CC#.<<>":#66;+15H"!'B),D/.8?(&53$)(/@4C-&.)(%0(1$7"=3#(;-#@?.%!%E?5@/),@??<G#94E&C9C!?B5#':H:/1<<8A.)H*,732
@r5585
TTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATC
+
3,-83:@$#$,/>9>!+"#0D.&)==FED-./E8+0>@9>A:>./.@'B3>8@3$88)691,AGB,"!>6)+1*'<-C3+CG
@r5586
CGAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACNTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGA
+
G5,?9-)G!56=G5<.6#';D*$16=.",*8<E-,*'G:2%D+8G08=@3>#26/$EG0EBG)E1>?4#8),9;01E04B'H.68:'*F7FF#G/(16#>/3)"!F%$/E79$@D:06DC1$=(+.1//&:0!;04!D,"6:,*;33+.>+:'?
@r5587
ATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTAATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGG
+
4/H558D-39:%%39=-F(0DDB3<,0+/;9)1!7":(2'(:GG9"+D*/)FE*53"2,@8.8F5G"/,D./44ED,28FD%.=<9=#C1)C$#;)$D.BHH7G+G%-'4%A?"9B7EGF0+745/+CEEH$E0<4)7'9-2=&*H%0'=<A5<B0A**?E2&2-*)+0H'4*?#B@7<F%<+.
@r5588
TAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATTGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAG
+
3#%$/F2.B"D#H#D8.D+6$##&+.B19ED!'092+<$"0549,EE-8$2G;';&D#0,,(E;B--A.$7(>CE*E+"8"8$H&-&DE;3AB6<%2G98%D@$@0"H4+5DA5D5BH;.*E<9,*5!(<*C$@%,CD?5:?E*86.&+0E;A#;9"!H@&#/&7->*0BE010E%#9;:C2?D!+-5;F=4/B229,D3C=G9(@<EH+<0->F$85$EAF@D$2&57!)=(!H:%&D(3,"&0*)G),>"/7$,.,F
@r5589
CNNATNNGCNCTACGGCATGGGGAAACGTCTTGNTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCA
+
%%$#)(!*+%'*')#(!''&+()*&$))'"+&+!+%#$#"*%$"'%!!)"$"*"+$'%!*)*)*!$")*(+&$#&%&&(!$&!##$)!
@r5590
GAAGCCATCNCCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCTCTTGAAAATAGCCCACCGTAAACGTAGCATGTCCAC
+
$/$;#C!B<0+F1"1<'//G8*%+F(/7F1@0',D0!-.@?D*$4C>CF'.<(-$C6=*3D;!*<CE.G)!=<4(D'$*B!1(/?E'"18<+AE!+):<%(+$2403*(&-9GC=#H-E+5&#%D3<:B*'A6-/7;&!F"B&$9+:AAH4
@r5591
AGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACNAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGANGGCCCCCACCATTACCAGCGGCGGCAATCNTCCGGCCTTTTCCCTGACACCGGAAGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCNCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGAC
+
CACB!$G+AE%?)+"""H>A<54@0/>+9'?0)1)C:E)0/>#*0<#7&):"H-7'=F2DF'EE9B6**-)C=3A.3A,*0,,E,;1F'/DF-+2)+&<96)1E(=.$#7E/8>87C+>',9H-(AE!&AD?-:%%G2"G=B7)&4:6D?*C;&'C80'A5,;%!CB8B>+)3&50G@,#A$.$;,0*$"6E+EF,,?680DBB6(2,%GA,F7@50784$E67($;=8"?<B&3/)#36%28),C:>&3GB2305"?018@2F$2(-4(!2<5@68DE(AF?%/H&A=)4?:#AD>(4/)!=316&-14E<D@F5AD=FC'0.F9E9GD9#@5(<@??37G#<*0&HB)/BF&)!$:'3<46:2,F0E>E"<:-!=/?@9A.F7(:A"D6E1'
@r5592
TATCCCCGCCCNNCAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGNAAGTGCGGCAAAGACA
+
*1"?>5E8:41;2!0A@FFA5B"@(3*D2)4*<>H.37:C6'5=0,&H<&"!A5?$$C(&64&9!95<2;;@>8.)E!F*H9#)H#=4:.6EB81:DG2%4A5G?8/)B:/4$+-'C$!;/6
@r5593
GTCAACNNANNNTNTCTTTGCATTTATCAAGTGTTTCCTT
+
!*(()%$$(#$!*!!+&)+$(&'#$#()%""*%*"*")(#
@r5594
TNGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCA
+
C5H3(&;1.)H2/#-G/(';07@</.?+7-71(-%+?E.E#>1+(
@r5595
ACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGGACTGCACTGGTGACCT
+
<.8E4C)39+(F4*%&8A1-#-"<;"3/E/66-@-,$*5@!$'0H&42@2-A)FC#<-4<B*+C
@r5596
GGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTA
+
G0<9;%;>?5).E2;E$8G32=AG02-D871$&=3#@B9=%&6:(FC!&9>1?99F';9
@r5597
CNCTTACTNAAGCCGTCCACACCGTATCCGCTCAATATTTTGNTTAAACGCCGTGGTCAGCGGCACCGCCATGGGGATTTTCACCACATC
+
'''#)*(#"&)(#&))%++!&&#%)$%+%("'!#!*#'%#+$!%#)%"&**'%*(*"+%(*#%"'%&()"'+)")()$"%&*%!%'"(+"
@r5598
TTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCNGTTTCTACGGGTATTGGCACAAACCTGATT
+
05!7B2F7&D3@%C-%>="/'/B9,$H@@<.8H/B4BBG/;F9"!C$5(3=!;%-@,/0/93H=@H<#6(
@r5599
TNTNCTNATCATGGGTAAAGTTAAACGANGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTNTNGTCTC
+
*!$"'&"%)#'++(*"$))!*"#%"("*"%)$!"$"&*"'&&+!$+*('**'#+)&#+!&!$$#!$+"#)%
@r5600
CACCATTCACCGTGCCACTNTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACTATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGNTGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGNCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTAT
+
6@'<!(,>$3/1;4-?C;='<0('##?<7,-?G3A1)<305&G2*H7BF>@7#4'205>))$%,%).>A;9,:0E12/B:2!"+#D65BD)9,-"CA%68#4'F)99C8&)GA->$@=.9*&.D::8%&'9-&8887FG0'B(BA"1<4B56+@"F+:C+?%-(D68%,#GE?7G-<"9E66
@r5601
AAGAGCATTATTCAGCGCCCGTTCCTGACCGNGTGGCTTACCTGACCGCCGGTATC
+
@GHH-44AF,C62<$ECGD9!@65A-9$E*GG+D2!'$$,+4A;$(&E=22,GC)A
@r5602
CGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTGCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGG
+
98F=9)"=??;A'",?1038B*;3F)9E(458B*<32'B&0F+590A;BF>6)=@-*-9%>A'F$;F3)571:3*C?79C0?<"F.)3)58$)DAD'47"10430"E,/@!1.672<;?;+'B!A;7F+/)$DB
@r5603
CGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGANTAGCATTTTTTTCATGGTGTTATTCCCGAT
+
895?F"G'&27"8%:'-!%DH7,=+!/0'"5F/;F>/)/76*&33.A!G.<&/.*=#28G'6>")C=G1/(74@!@(8
@r5604
ATCAANTCTNNNANNGGNNANNGTNTTNNNNCNATNNNTNNTGTNNNNAGCANCTGNCACANNNNANNNGNCCGTTNCNNCNNAATNANGTCNACG
+
$$#"$"#$$!#$$$$$#"!"#!""!$$"##"#!##!!$$$!$$$###"$$"#!##$##!$$$##!!!""$""#!!$$!"!$!$#$$#!"$$""#""
@r5605
NCATTTTAAAGTNCTGCTTGCCATTCTGNGNAACACCTATGGGTGGNATAAACCAAT
+
!)+&#+$!!!$$#$!##%'!)"*'**+!"$')+&!$('#(*'%#&'$"$)&)%&$*+
@r5606
GCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTNATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTC
+
H$?&(8BGFA;',60')+=F8#:1/6/"?!BD?0!E=%%5-*&'##/6$8*G&+G6#F>:DC#D@<.E@DEC2B6;B:"6;:D!7*C7F9%+E0#2#*"H,%3*/35>?C7(>'EGDH%A/D-?+?<"@-!%,=!!7,)81
@r5607
GAACTGGCAGNAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCG
+
@H40($:>?CA.*7.&"$E7"#,&DG*B/9(&99+E1,*2EEG5)GA$<6(D.?;H)H=4*&"9H;=.;4"&/9
@r5608
AAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGCCAGAAACTG
+
'"&+%""&%)$+'($$'!')'('$&$#'*%'&(#"(%%#%#""+*)(&#)
@r5609
GAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCT
+
<'4+2>;G4=G-.3<(:66*C<!.C?E"E-A4'?,C),.5>@0
@r5610
CAGTTTGTTCATCCGGTTCGTGTAGCANCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCT
+
=@.)@$9!F$&%*(6"G3%1#'./935H7E#.&1?BFH8308$0G1/!=4);<@9B9E!E>(!?E!F5/0#$%F!2=8";F$40%6HGH/7E=55:>+FF-;A7;.248:(&A.(>7B65)&0?7/+?.'(HC@?E4D0F:FHGH%!7="#3.7/3:5CC,-*8<?GC;*&C)/D09'=DEC8.*!8H*(B7#2G<<F81$<<9%/4F="+B>C#9>5&GA=5@H."/GC8%2H?H+>+$77?F!B,4:1#2:HB<,7'0;#E@83*:#2B"=(FHH$($76>CG-!9FG,;C5"?@F*?>GA<B;,-FH
@r5611
GCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCG
+
</5;0!G-)&#)&++$2(=(=/?A@><35/4&0D=#-!F3,7#'287A7F5A:F%'5#(9A8F.6
@r5612
TACTTCTGGGTTCCTTCNAGTTGTTTTTGCATAGTGNTCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCCGTGTCTGCCAGTCGGGGGGAGGCTGCATNAT
+
(G$"(#:7F4(5@6.$@58#140&52>C'F,E887-*90690:EF=FBC.20=G2,D%);</F)D>"9A2@0*?F#G:!',>C+/(8G0A&!).'DE-'@,'$!6%
@r5613
CACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACG
+
'38!$)5@A$>1&?-)+'<<+5;!A(""E&22.'99E*;;1*!-?"*"$0.72.7"GA+C6)@C'1.$!!6@9=3&8'%"2<<G:
@r5614
GCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGA
+
79)7;F5..9>%(H.B*B!#/E-:E(8:&("*#":&=@B34=E'G8C/7:%$
@r5615
GTTACTGGATTAAACACGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGCCATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAG
+
%7@-B:8!7;-GG$$/&;49815/B)D4465@!'A)4$+::B!-&%*/E;)(3%954'=9C4&+,9@E*!/E,F&05H(E#8'/*/*)&C*24;8)@G-;$4E&2'0&D87,,;A%)-:>G&66"4E!G#C4(/0H9=79)6A'='5!&(.+@;+!8A(/"(";AA4+)'C6B
@r5616
CTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACC
+
E6=BE+G:'2<.B,G"C2E"2F/B5@B'4%&=;,!11(&@G<"CD4G=;21
@r5617
TCGTCCGTGGAATGAACAAGGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGG
+
+$*)$*%**##''"))!*#)'%&##)!*"!"'$*)!&(%$(#")%)+$!$$"+*%%))%*'%"&!&++$**+'#&*%)(&%'$''+"+))$$"("*++%%")#$&#!'*$'*)&'*&*"*#%$'
@r5618
TNNNGTCAGTNNTGNCAACNNNCTCATANCGNGAAANGNGANNNNNAGAACGCAATNAGANTGANAATCATGGTTCCTGCATATGATGACAATGTCTCCCCAAGACCATCTCTATGAGCTG
+
)#""%%'*$%#$#("$''$'$"*'%)$&"#$!*#*$!&$%%!#"%%#%#&!)'('%$(($""!!#+%"*&''((+*)##!&"!+#**")#&*'$'+%%&#'+&%$%!#&%*)*$*%!)#'(
@r5619
GTATACNTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTT
+
*$%!)*!"+)$)$'$#"*+!$($$&)$%)*+&*%(+*&!(+%'$$)#'*(&&*%*"
@r5620
CTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCGGACT
+
2/@2G)D0F8B!(5D&'H98"=3/#C@H0<AF<!7>/+<*#!@-+=@2-H,9E8F5E%9@:6B*?;<
@r5621
CCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCNGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGA
+
GE>B)1.%'6B0*(F:,3<C"(7,.*7)H/$>&+"0>')-)"+:D!4*):E67F!G2"&C&=>:C#8=@H#?0&C@2.B;C1G#D.$@:?A/(3+5C+AB')D8E7))
@r5622
ATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGT
+
AEC=66AD'@##0B3E+5,57:@#450'&,):==>1/2D!4%*E9<6>.@123)GG@A@4+.7
@r5623
GTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTNTGGTTC
+
6@;G2G8:8&7<!$946(>?/B"8B01;E.H%8?/<0>7C--&AE
@r5624
GCATGNNCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACANACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGNACTTCAGGCCTGCCATCCAGTTC
+
*&*$$"(+%$***##'"&)##'(&(&&+*')##+!$!#%)#%&)"+&*+&'$$&+)!#!'"'(('##((#*'"$!"'$*'*%(#!%"#&#%&+'+)')()()!(#&%!
@r5625
CTCTCNCATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCC
+
+BD.$:33<;*G)$6#+>B@$%5:!<.H*3HD"7C(*50)%:!(?2D<;:2H%FD+H-24<4<0(440.=B-;H#?G@>=2/>$#7E:2G>D285?.0:8;+7<<"G0?E
@r5626
AGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGNTTTATTTTATCTGAACTCGCTACGGC
+
)4C9;E3=C248D6?%A<<??:?A#+>'$)F:.A&A,A&C9/DF??=B5.E'4F9!,64D93!>CH!5=E#,<;4<*8*:;4D#H9/0350D)E=77?8C,#3,55.?:$%23@4;$20!@'"E%!(#-.A$@:?')D;"F7#"@&2*1C8C3479B>4+!&&!/EE<":?3)238!H(3,F%10H;&&4HB+H;807==8$)G9H2)=G3C6#<'"44E5'(
@r5627
AGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGC
+
C96F>9=,:>"?4<H:05%$7/%!?7,!'C-,16#!44D6$6F.4=D3>1E@7(-5E2!?8/>6:D9"9/H-/2.D8,78#HA5(+$E@;.D##
@r5628
GGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAA
+
5#G+A.+D"A@,G,D#"$76)5,&0$!56&6)#A3'"80.5,$A+C8!D
@r5629
ACCTGCAGGTGATGCTTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCACTTTATTTTTGCTG
+
HC-1'#9H8A5<"26=0<4$A4$F*'$!G%B8)#!!!6!B)>'0@!,*,$":9';AH+10F@-:CE6%762+!H'C,?E9B$DH5:/
@r5630
AATNTTTACCNGCTGATGCGCGGCTGCCACNGGCGGTTATGTNGGTACACCGGGCAGCATGGCAAACAGCCGGTCGCAGGCGTCCGGGACGTT
+
$%!+%$+%)!!&)+%$*%&++*(+*$%$!%)"%+&"((&%*!+(%#"*%'"$"!!'''")&)#*)#!*++"*#%"%!+$*#&*')&*+&++"%
@r5631
NGCCTGNGCCNTANGCAGGCCNGNNNGGGNNCNNTCTTCCTGACGATCGCCTGCAGACACCTTCACGCTGG
+
$*!*)($"$*"&$#((*(%&%'&!("("*$"*!'*+'#*$'%'&*($%#&!!)&*##!*%#*)*%*"!#("
@r5632
NNCANCNNACATTNAGNNCANNNNGGGCNGANATNNNTGNNNNGNNNGTGNANGCNNNNNNNAANNANANACTANNCGNNAGNGNCTNTCNNNGNNTGATATATNTTCNTGTTNNGCATNNGNNTANCACTTTNTCNNANACGGNNNNTCCANGNNNCNTGNGTCNNNCTGTCNNNCTNNNGNGNNCNAGAAATTTNANNANGNACNANAANGNAATNNNCTNNNNCAGCCACNNACNNGACTGTNNCNACNNAGTN
+
!#$#$!!$$$$#$""!!#$$!$!!"$##!"$!$!#$!$""!!"$!"!"$$#!!$$!!##""!""!!!$$"##$#!"#"!"!"$"!$"!$"!#!#$$#"#"##$$"$$""#"$"!!!!##$#"!!#""!$$$!"!"$""#"##"$#!"##""$#$"$"#$$$$#"!!##"#"##$!"$$"#$#$$!""!$!$""$!"$#"#$$!#!#$$""$!!"!$!$#$"!#""$$###!!#!"!#$!!!"$#"!!"!"#$#"!!"
@r5633
NACCCCACGATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATACGTCTACGGAAAGNCG
+
")&+)+&#$+"(*)+"))+'&*#(%&(%((!(#%(+&)#'+))"!!"%*+)')*$&)#!&$&('$&*&'!#(!*&'!+''")#*!)&
@r5634
NTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAG
+
#<$.AF>'@GCA+8C3H:=+;(%,2';G*$:B,,C3+&;@H1&293GE1?'CAB-
@r5635
NGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCA
+
!A<=*C#-,0D.629,/9'<(-!/3A++(;9HH4;*:<G51H
@r5636
NCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTT
+
#?3AAA8;B:>-(@+,F%G<'HB<5A(3,H?6'1.4$2).GG>43)$?(0/>6:$+-5"##%1+F,-+5H
@r5637
NTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTNTTTTATATCCCTTTTAAATTTTGGCTTAATGACTNTATCCAATGAGTCAAAAAGCTC
+
!A:?D8;'7/*/:DA+<?83A=AA6>#&->:?1$,-@A<=!0*D&%.AGA7(@:<#=<6487*+3B4.D$4AD(@!*4'"8G$?7$H:G8:/7$=G*#:&?B9C%E6/D&4%F2216,F4B(28
@r5638
TCNNGCNNTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCATTCCGGAACGNTACCGACGCCGGATCGCCC
+
!!#"""!*+%%($(#*%**%#'&!&#)!'$'$')(#(!&'"&&""#"')(+$"'('(%#%')!&&+'!&$")$%&#$%+!#&!!($&)*&&""
@r5639
CCCTTCCTGGGATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTGTGGNTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGANATATTCACTCAGCAACCCCGGTATCAGTTCATCCANCGCGGCTGCTTT
+
(6<A%@/'&-,+DE4/GB+>&'G!H*'>HC4%/6,"-+"=+$"C-52H3(,7F$363G=<@311,BG"<94#47=A*0(46>GF2?(G+&>F("#?7<7E0E8AH(#"C6D&C4$<>29D7*AG*0>1&A94=#,)$)<DA*2=',*%BH?1$,A@-*D-*2&*&-#,)0<1=C(,.+H98@BF;/)GG
@r5640
ACCAAGATAGCACTCGAACGACGAAGTAAAGAACNCGAAAAAG
+
D)G16@)4,3)>8?CG#30D>)5"1.GBBA0:"*C/84<.@B+
@r5641
CGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCG
+
F,@E4?,;5D(1/6#*H+);7-(9,1:(,386G.!&5+#/@5=.?D;,>39*<BB320-#>(H@**#H/?5E*7!+87.02#G+$26/850G6(08DE1)2)/#>;%
@r5642
GGCAGGCGTCACGGTCATGGCGGTTGCCGCTGTTACCGTGCTG
+
+(""&!+'+$#%*&&(&#%#&%#+'%!+(('&"'$#($*)"#!
@r5643
CTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGNTTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAAT
+
&:65&4%;,0/?61A"2>5/#0F#*&/5/E:=@'$D3C5,G7&$(9)=3'3;+-0D>06/:?+FC6@+<<#*2>EH%7%,/&DG#FG#=D9@B$7()%11D#=D9&!2D&D8;?DG#:67#HF!HC*=%%2A55F*$DH3FC&4E?%>7":4"%/84?;$'/(2<2HG-2#)&"G&5#A*?6<)7
@r5644
NCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATT
+
+H>36$G,;H,;H66)B%BB5HH%)+H"=@/);*E860?''0.%?
@r5645
GGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCCTCGTTCGTATTGCCCATTTATCGACA
+
-=D,@<F(GH/%+!4$>4",FD7/D&425(!#="6F;5=E&&/->)'C"&%+E/&)HE>4)%FE:C9$($8@2
@r5646
ACACCCAGCAGCATTTTNGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGCAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGA
+
9E(3/D&>D8(0@/1,4G!-2G05*3.#*4-"6*H#==8#4:;42@?!/A>&:G11B%5&,9+F/#D-1<("(A6C>=/%?C?*A-8<=?'<#GE#-8>>;><)?<*32+;D#E(@$$0-:8*$)722:!>%98+<F*;D,9-H84%0B1
@r5647
ATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGGACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAAT
+
1)A")4'0#B.B='!'71?690*2*<'+?/:>&%>6E<>@8C/"!'!%@,(/@3@!HA)/*5F1AD/153(26G-/;8@H:,6F6E8%"E.(!9D:7=-?E-,$*@5BG
@r5648
CCGGTTNTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTNGCAATGTATGTCGTTTCAGCTAAACGGNATCAGCAATGTTTATGTNAAGAAACAGTAAGNTACTCAACCCGATGTTTGAGTNCGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAANACGACGCGAAATTCAGCATTTTCACAAGCTT
+
#&!(!($*'#+"""&'%(+$'+'"+*#*'%'*%))*$%""("'"#*+%*"&(&%%)""*+)""&'!")!*+$)'%%$(!%%$"!)!$"$+($#!(%$%$('*&)$*#*'!(+%)*')#*"#*"(+*++(+"%&')#+%($#(#$"$'!###)+&(#&!'"%)&$+$)+'&!*()#'")(*"$)%+%((&!%("#!&"*)()&($"&**#"%%+%##%+**($($%"&!&'(*#
@r5649
TCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCAT
+
@G$;-#G2?%HF3H&;#!"A+&34;,6B7D*98@6C/G@=;C3+%,&?GC"13H"A7B$091A#:8-/;8,72B#4BB+F'B#:=-87C"8:A;378.#GD=B&%;H/"-BH"$A"E.%9%":7#&0),?)
@r5650
GAANAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAANCTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGC
+
&E4<#$<D?!E5>;B7A5.+H24G--,5:"G9H=..A!,:3=.*(<:A7C-"3<+.%,)#/HDB$=%@9/:1",E5;2AH$4F+*!>C(@$=;,,?>&,:@>AG47(&%9<#-<#&.'::,+<E!@7(7A7".)A$41>HH568D0A:%F6<3*08,1%H!.:H$2@**$<'%:=35!7,>EC1,4<=<0246**/D
@r5651
NANGGATNGCNCNTCCANNGGNANTTNANNATNNGNNCANNGCNNGTNATCANTNNNNN
+
$####$"!!####""#""!$$!##$$!"!!"#$#!"!$#""$!!#"$#$"#"#"!"##"
@r5652
AGCACCTCATTACCCTTGCNACCGCCTCGCAGANCGGGCATTCCCTGTTCCTGCCANTTCTGAATGGTACGGATACTCGCACCGAAAANGTCAGCCAGCTGCTTTTTGTTGA
+
+"&"(%&#)#&!%+)*&%'("*%$)!'$"!("*))$*'$&$&$'%!%$%'+$$#$)))"$!&+'(!(%&*!#!$(('!+!&*!!&*"&'%*%%%'"!%!*"++*$&!)&$&*
@r5653
CGCCNGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCA
+
2DE,#F0H,%-*.13D!<'C4@(3+"A>'4;%+?3(0@5D4HBF$H44/+6:/D!9,(4E=(3&*F1"2+9A);
@r5654
CNTCCCNGTTGTGCAGATATAAAAANTCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTGGGGATTGCA
+
(#*!$&$%*+%#%*'&!))$'($%$%$"(&$!&'++%&""*%#*%%%%!#'&"&'%%)%"('+)"*'")'*$$##!%*#'#+
@r5655
CNGANAAAAACNAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGNTGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTNCATTCGCTAATCAGTGGTGGTGCTCTCCAGA
+
$'")#"+'*$$&*"&*)&$+&#$$%)"!"'%&)*&'$(&('#($"('&%)#!)!%'#&+%#)(+!%"(*&+#!%*#&%&*#)'(*(*$$""('+##*"$"%$&%%*!*(!+$"+')&&*&*%'!&&)")!'+'**%'+#(!!&#'*&$#"&)''&#&&"$$&'($'&!#*!(+"#$"')!!&)(!$"#%#$+&&!%(**!%%(!*(+*#'!)&&&)(#%'*&)'&('')%)*)%")+$(('$#&!!+&$+#&($%%)#)'')*%))(*(
@r5656
CCGCGCGCTGTCATTTNGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGG
+
:'$;<"?$.8#">F405#'#.3HB/%>BE5E-F'(&&!0:84A+8!/5,3@C".06("GD885E=,)!CAFC!=EGH:9CC7!8606:
@r5657
CCCGCCGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCNTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAGTATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTNCACCNTTGTTCGGCCGATGAAA
+
"''&)&+(+"&$#"&%**+*&#%$$'"&'&%'"+(%!%"!'*&+('*"!&+"#++&$)')#"+%"*"&"(+")##&*%"+'(&*#+"$$"&*+#("#"($'+"*+'(#)+$%))"+*'("&$"*!"%*"#**&$*&$"%%'()'+""&!(+)$)$"(%%"+"*#%$&&#**))!%*"$*'#!(*#$#($!)+)%))$&+(*$##)('+#
@r5658
CAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACGCGGAGCAGTTCGGCAGCC
+
14;$:&5D)/;/+4-)-0)*B!-H7#64H::=%G1+$6-##(/3=)*<?7F:+>",13,("
@r5659
ACAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGNTGATGCTGATACAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCNAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGC
+
$+*&"+%#&+$!+"+"#"%"%%+&+(%'!$+'&)+$+&!!+)%)#!#$'&++''()$+#)"%%#!"'+%")#&+)&+&%&$)"+')%")!%+$*%*)*#*#$%*&!((&)+'!&&(%'$!*(*"'"#&'"!"!#+"!&#'!*"&"'"*$$(++%'())+()$+&"&($+$(&#%&%')+%+%)"*)+%)*#+"))$"*&$(+)'!#(!((+*&'+')''&(&!")!(**!!#"&!&""+'+""%%''"!!!
@r5660
TCGCTGGTGATGGGTAACCTGCCGCCGCGCCCGTTNAATATCCGGATGCGCAGGATGGCGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGA
+
A25((-3H'.+('6@;,83=*"*62&C2FGG#!<&>.:.AC.;1!,:,AFG7+F(85""F+,5-;GD73676!4E,?/0E?;0)'H,!:H@9E@*F+.!4B1,GE39"0&!550+?
@r5661
TTCATCCAGTCTTTGACAATCTGCACCCAGGTGGTGAACGGGCTGTACCCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCANGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTA
+
=#!8<AH2:#1,'5"EF)7C=;"H0F3:!D(.6=H="E.#&+H!-%DE+E+D3:1+5B,'>G014/<D&,,:74:23"H-)=)@8AF>)8A-640"/G4()%6))78E(&!23*'>+(F6!3<#!4#B6?3<8&CA'9B)D'2'D,8E$-.6.?H&!59BG.7&3&--*HH
@r5662
AACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGAT
+
5(0.-,$E:$2#>.1&>"'(1=?-$&C-*3G4;:GE:$9E%?*
@r5663
CTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTG
+
&+!#%&)&$($&#'#)+!*'"+%%%'))!'$%$)""*'!$$!(+&
@r5664
TAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTCAATTCTATGCCCANCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCT
+
250HG<>1;:$6A$*BG,9AFF?<$626-:0,>+?G@**7>(!*)?B.=;E5B@//8+9"G72*;2!;680;:!@4697-HD!)<-!C$2:%&<<5*9;>7.!E*0+D>".C-H49>-G!=927B="B<4;'09&4&D(!??<A7D%*C<%C5/%29E@G<7=)!'4H>"@&H%6+C5
@r5665
NTTCTGGCCNCAGCANCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGC
+
%#++*+#&&!%$"%)"))%)&""*''"#)%%)$#"!'##)'$'$+)&$")+%%'&#''+%*)*)'%'(%#+'#&+*%+#&(&(&%#)("&"%!"))%!*""
@r5666
GGTGTCNGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGAGATGACGGAGGATGANGTAATGCTGATGACAGT
+
E!E74E@,;>$#@3-'42-$/G;@54E-E(1E4-*)5>40AD/A0%:E=4&8'/*&*>D-+G&../*+%G=#7=7G8&A..H6B=(8AC%"2
@r5667
GCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGANAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGACGTGGAACCNACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCC
+
'$+'*%#!'*!!%+)**!!!"'%$%'")*+*#))'&%$)+&*&*#"&*#+&"#)#(*)+)($(+&!%&#+)$#**+#'("*((%!*()!)(*!"+&"'$$*#+'*')$$(%%%($(%(+++'"*(!%)%"($(%+)+*'*+&(!'&#(*%"(%"$(#+$*!$+)$#'((&%"*#+()'')%"#!&%#!'(#"++%+)!&+(&%*)(!#''
@r5668
GTATCCGTATCCTGAGCCGTCTGCAGGTTNAGTGAGTCACCCGGN
+
#005'>-62/.9%7C$;<E#2F94!:&$1H"?#G(5@1;8B4D<!
@r5669
GCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGATCTCAA
+
&H&4D6,8:(A(/<-.*-.5-.CH@8>FABG3H7/*1<'.#64829&25'1/1$%FF-,&6$=E
@r5670
AAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTC
+
9$3!(G?,"(.64/2%/)#<C%="3&#CAD;F?D$8'88>4E.),E8/5>%7#=>B*"!
@r5671
GCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTAT
+
>8C7243<#%D-GF#C?#*F#C<8<'G-$9$422C9-?B.-,7
@r5672
NCTGTCTGATTTCCGTATGCTTCAACGAGCANGTCTGGAATGGTTTTGACTGAGAACGTCA
+
%F:AA2,C*;F>:D@+6'H14HA&-).$2=.:"7H5=?G;7>%3)14<(3:A'8@3FC7<,
@r5673
TCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCNAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAG
+
060(#!%"*>@6485D3:='#22>-B'<!4A)F(&B7+--B'C*@F+C=>0:27B+H3<4G*;&A$)-H+#-,1?6F34$@:<AH-")F?F<=C4.669(%+6GF1$!#H
@r5674
GGAAAAGTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGNCCGCCTGC
+
@0!F#HHF<*%-'91*)D8!F,1>DGCE:-*"-9@30!$A.8F:1(0$66F/,D>48*<B1<0#
@r5675
AGANGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACNTCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAA
+
"'$!+((%'&!%'!"(!#$%%((+*$!!"'#)*+!*)&)!)$*&+**+%*'$()*)&&+(*!+#'"&'()%$*'"'"*'*(++*$(*!+")%+!!)*+*)"#$!(&$**&('&+)%!&#%("$*"+$)+"(+(!$')$)%"($"'#+$&'$$'!!*$+%)$!#!"$*&(%#*''*'*&%
@r5676
AGTGTGAGTTCGACTGGAATGATGGAAATGNTCAGGAAGGATGGCCTCCAATGGATGCTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTG
+
"?>61=28<3&@45A0A+1+)BB10H*3@?/344D@?4@A%8@+<5(D'!?=3"6H/81F>1:1D5G+=(E;!>$'EA?<GF29&;/>&-#A$=>A#12:1/@?&A1;*G"H%%A4>6EA4,EEH,1B%.,HD1DH1/&;:@5"2"E@CF!"'.D.5E:90""9<+?.:4(8,D%4A0.$*42<4+.-D5!2)C@$:$=*$-2A=8;>7*"4?+@DH52#>%:DDHH@.8*<3/'<,70!%88
@r5677
ANCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGA
+
0;*($;G=B<"-6E2)&FA)1-A(:F>,2>/<>AH+*F"&59"?;3+#E/#0=?3+E+(8)!
@r5678
GGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTNNTGT
+
+GE);7/"'7%A1:20*F5"E,9D!;7,66)$/<6#&%&H1E94?(%5?<.&1G%/GD;4.">$C,%-!CA1G8A5+49!C.;@E
@r5679
AACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCA
+
<>E0D<7<#1.3<7'=4%:=32.'/="(-A"$(#(D*3+D&&B+&,GB#$)C))5=.@8*?H!E"=A6;/';6!?(@AD94,@%"#3+#,B,6%!B0'@D>+,.918,E=-A/BH$#F1B;6G>(
@r5680
ANCTGNCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACNTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTAC
+
)$D+H(!C'1!G+C(>E"9!78@++1.B9,EE-.#*8#*(>%;=FHE8CG&@D&D?:,"C<&8=G/>/H?8+F?B($C%'F4<>-9%D&3
@r5681
NATTACNCNTGNNNNACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACNTGCACATCGCTGGCAAACGTATACGGCGGAATATCTG
+
#(('&#!$!&!&"$!$**%+&*"&#(""+"%!(%&)$!(%'!%"&'($&)#&'"%%*!%+!%*+)'%"#'&+'*+'!%&**!%+)$"#()%&')$*#'!&!$&%++)#&+!&)&*%)$$%"")+%*#(%"#&"%'*!$+'(((!&""&!"*++*
@r5682
GCTCGCCCGTNAAGANAAAGAGGCAGAACTGGCAGACGACATNGAAAAAGACCTGCCCC
+
<#EF%D(&F6'!)>#B#>49/HC-G1#;$,B'%31+'!/:#)!/-/(%+%EF=2;'$%C
@r5683
ACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTG
+
>D@E(DC232G40$E"!4'7"AED'95=69/$!?00?3)$?99=*G-A?G
@r5684
GGTGGATGTGGCGGGTTATGATGAACTTGCTGCNTTTGATGATGATATTGAACAGGAAGGCNCTCCGACGTTCCTGGGAGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTG
+
873H5C#F!E'C&!96&+H1&BB'H7=>6:40<<,#E=:E6<;F?55B($?">D;7G>"1.6H:3?7$*6#-4!!1"2A65,3E;>C68G*G%2:#19&67F9$$1-,,@(;->4?E3D3!$BH549+*BC87-C./B".,H8!$3F&32>#<-!$*GE5&>B2@.=#,@*7H,*%78##A:=)75=GC9?$E#1>2D'A>'@C55:
@r5685
TTACAGAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAA
+
&>&<+7&&+HE8>D#!-=!E92.*:1$+='75F3,"C6*F4&2'E)1(C&G&/D41E#84C0>/?@=G*A2E9F+4-6);!"GFG<62/DB:"GC-02,7CDAG4@;?C5&%!3:!>""(9:.@D7?">(*/!8,D.-<GF64FFH2-;<=2=@:(7-F:/!7&%;@()%766H.>8%5?++#;'6=$)-57"3+"*"&:8:AC1@;,B-6!43CH6+$,>"<&G($E4=6)$=D91B$+#:))F<0<"8$""6?.0@FB.G9:&G@
@r5686
CCNANGTCATGCTNAGCTNNCNGANTTTGCGNAGGNNGATNTNC
+
&&#'$$)*!(%''&*$'#!$'!)("'**%!&&%!'#!)&&!"$*
@r5687
TTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGNACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGC
+
D:(4"01!$/!.C$>->EC,'&;.%"'99+G&>3=*40-+G3%";3,5--8)1"2GH4CCDC6-!++$">:)/E(A!'860H%/H@(7H+!';/.:7=*1775-;H>HBC#&C'B)&**#<#
@r5688
AGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTT
+
(2F@%8G<E=24))7H;="B@<$7E2?5!=&%#F7#E161A,,")DD20:?0HE.-?D+627)@6#./.&2@3DH+"-%D5%1';/D&4D9GD0=5@!
@r5689
ATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTNAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTG
+
0>/<F"4'%#3=/??163'3D(*8$7G7,;#BB5A./9+-&>%';C>6362#FE+HD*7=8!(?H62#/-80'57/(4D2/?C@57#7'=C'H9A.+%-#
@r5690
TTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGNCGCAATTCACTGCGGCGACCGCGA
+
%$:E;7F84'28A#?4"1/5,$+4@(-*C<3C:')*-@8@/@2H3HA<2:5%+(%;D#(/.F(17)<>4"4EE5;CDH0D0%&DB;E@.ADC<G.
@r5691
ATNGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCT
+
)'(++"!*"(()))*$"$))(($)%)#$*"'##&(&!)')!+"(!!%*+'"&&%)'#)+%%&$&$%*#
@r5692
NNAACTNATGCNNGANGTNNGGTANGNAACNCTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCNACCTGACAGAGGNCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCANCCGTATCCCATTCAGNGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCNAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGNTGCGGCGAACTTCGTCAACGGAAACA
+
!(**($%"(*'!%%()!&!"'$"&##$$%%'(+%$&&)&'!"##&+''*'"+$$%!$''**"(""#&##)('()&#*!(*"!#("%$!(%&+')%(#%%"!")#%"$!!&'*'$&$+'!&&+"*#*)**""))$*%&+#((&#"+$(!*#%*+(%'!"%"+$$("+*"*!%&$%!*))*!$($#!&(#"'!$*$+"((("$$)%+!#)*#$#$(+'+$("'*#$%$'+(#&**+%''#!#!$#*)"($+)!%)*+#&!(%*)$''#)"('*+"'%#+$(!#$&$'$')!%")*(#$+&(#)+)'"'")**#"&+!#)+'!"$(+$#&&!)+#%"()&(#&'*$*+'("#+$(('#'&+&+*&"!++&!"+#'$)
@r5693
NCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGA
+
.B=,$:G;B*2!7:2C<+0=".*D9%39+)5CF%(4&4!6E8
@r5694
CAACTGCTGGCGGCAAATGAGCAGAAATTTAAGTTTGATGCGCTGTTTCTGCGTCTCTTTTTCCGNGTAGAGCTATCCCTTCACCACGGAGAAAGTNTTATCTCTCACANATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGAT
+
+08<@(0?@C-,16FBG4?4';:$&DGA/.-DC=5DA%/DC.B*08F.E"0>6&0597=/<':@;3F.(&>F7<@E?2&AD2+C?3C;,3<&"(=66)39/,)!#B+=8$GG3D05%@='!-;6(80DEEG9/40(B7B=)/%=%G?:=1:
@r5695
AGCTGACAGNGCCAAAATAACAAATGCCTTTGGCTTCCTTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACAT
+
5*%-'H??,64A--@E$'41<E3H8HA!F2)0"G;"*H(7G@'!;,***1-"?F%#E$7%="B6F/HF*;44=GDG3'B++/),=E,-:<08C/C)C
@r5696
CAGACGTTTACTGTNCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAAC
+
037>2F>%79+';#9A<1'+9?.<?.,/*+4(/39C''BD".%32:'(!4
@r5697
GAGATGGCCATTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTNAAAATTGAGGTGACGGGTTAAAAATAA
+
*0C"9&-%4/+6902-/(/*@!6A(;EG$#?C6<C=(E91%E6:$0%E5)9,$E@G1/GE()B%H%@F?.",;5?F7<DG4.B@0BG/D<(9G?@<#=7A';:;
@r5698
AGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTNCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCNCTAACTATTNTCCATGAAATACATTTTTGATTATTATTTGAANCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCAATGTATGTATTGGTTTATTGGAGTAGANGCTTGCTTTTCTGAGCC
+
71-;4>((:FC9D0=D0/+E3C4C03'$,47'!?!64AG8=A>G)&*#+%40A*D%A"':AB7;8B/&11:0?DF.F&0-"(!EE;=A@CH7':?=7=HB+CH8)C?,H0,3+8>>@&0/%!.&A8=-7'D&@42#8&03!7<,*$#9,=6BE697C=17G5<C&,-3D$E<3'@=*AD6-DC2,$9?#0F1AD%(G1EC0+9)A@'/#EB$E*0@68?2800324'A/H</6..!E;?;B#2@)0C48H0:(95$1/;)&7-+((F)G(&+.$"G).::)'=5C"/>.(-:$$%0;3=H,E@$.5.87!::1DC<#.=2G1%732$
@r5699
TCTTATTCAATAAGTCAATATNATGCCGTCAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCNTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTT
+
#!@4E9A"?"#?A+>HCD99<E"$6!=12>0#)"!?5==E:$&0FCF!:B*;)<'F*5')-67F&9>?//&)8D#?DG?5&&8F/?)=/E1C*"(>!6#!(#=4EF)CH/EH?)&16*&C#3F2'/:9C=>H1E82".23;)9/
@r5700
ACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGNCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCACATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCNGACCATTTNCATCATTCCAGTC
+
$GBAD!2/*@F:0D+A>6/47!?&)EC0@*4H%,2$GC.6)?(/22:*6F<,!")@)=;-%:3E&GH&!68.B'%-';C#E5/'--.C11*E!AED<;%-4)E2G0G1)F)G4<=4?C+;>F,&$%*!<>B."=2)=7A((%7=772*.&E$>7/(?%D.-&/?@H'D=:E"+6BGBA7EG29*GB-5#:93/+6*#80=):/-@GFA)9.+)0%C9-"">7F)D5BGD!CHG4GA80"F:=:4+0/90?=G%%D(#:H>H>$-/(+DF"
@r5701
GCATTTTCGCTAGCAATTAATTTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGNTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAG
+
+&&)((*!*+'*#(*"&'""'$$)))!"%+)&("+(!$'%"!'!)!&*)'!#!#%%#$+(*"$*##%$#$!+(**+)##&'+%*!"(%+%$++++)&&*%)$!%$()&#!
@r5702
AGACACCGGCAGCACGGCGGTGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGCCATCATCACCGGATANTGCCAGCGTC
+
$)$&+'+%"*%('&)%'(')%+%&"'&)*&*)+$(%&)*)($'&('&'*%+")"((((#!$%$')%(#%#"%%'%%'+*+")(+"+*"
@r5703
ACGCCTGGTCGTTCAGGGATGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGT
+
)77BA415!G@*-'9%@H);#4<?C>26G##&#+5*DE2/"$=C7@+8E,ED>7#;(%F8*9.F
@r5704
GGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCG
+
<'#FE.A$"'(*0;;D#H=G5>H?@>;13FHH2(+6?"D97.9*@E2-/(;)>!D?,;5(?7)A5**-D8'<:,6-&<:59H641,#?)?755>@,":7;>*@+,+/6.4)71$!1?//2,?BA9@H,//8FH(GD;(0@E4-<#AA//%F(<B"B:;!HBFA@$C,@
@r5705
TNGCGCATTCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAA
+
(&$)+)*!*$"+#)+(*##!*!#!'%+&#!)"#%*)"($)#"&#(#%"&*+(%*(#"%*&(*)*
@r5706
TATACCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCCCGTATCTGCTGGG
+
G//4C0/!""0H<8F40'(!/H::/GGG,7'#10F>06(A3<$6:5F?"3%A)=
@r5707
CTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACCCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGA
+
B8!8881B(+$2E/6AD5$F@53@@*82";?'F@D'-,:6!<00*=16$$@#AF8!#**9AE&52/?@7F+0"8<5:;<@<'!G61(3.HB5"'?D(?++:D1546A8E=!0/2235<3.A?9D!F4C5EHD$+3#G:.<@H%#/@*F7"5#H<5B5F-7,,8/';!==-AHC7.(7=)=256D/E),1>3A69;A?$,
@r5708
TTAGCCGCTTCGGTTCATCAGCTCTGATACCAATCCACGTGGTGTANTTCCCTCGCCCGAAATGNTCATCACAGTATTTGGTGAAGGGAACGAGTTTT
+
;<C1.6>(!6GE).0GH$HC2FBB1@@<@6.C08D348E80"&2F.!E1&&?(!E$(!:B!C1608E>)BC?8+H>32972;#-/4!=E.1..#DB21
@r5709
AGCGCANTGAGATCCNGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCCCATAA
+
E>@103%0,16<BA;@6><&2B?:(7F'7H8>"D7301E-*)D?!!&+F/*'7(-B7(&8
@r5710
GNACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACG
+
@#45F$BH(@)CF8%6E.$%6(7D./%H-)@B9@.1>:>F+@$D(0*")!9*F9H;-EG</@->
@r5711
ATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCC
+
GC3=6<<GD)$-&$/'<C:C@$H(=#,0:)6FGFA%H;C9C!.?!"3$+C'=,,%*!<4@!@#55.AE.-92G;?&@)F'A(3>9?,
@r5712
TGGTGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCNCGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCC
+
&!&"+*'$+#)(&%#*&')*"$+$#*+&+$)+'"*$#"#+)&!$$$(%+"&(%*%"&($!"&!!*%*$%%+!&*&%!&(%(%)%!&+%$$((!%+
@r5713
NNAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGACTTGCTGCTTTCCAT
+
0#!0C'G!./)609)?/,G/'4/E-,6?,$;B7*(E#2:9&2C5=C%DG(91</5!:/#/A0$
@r5714
TCTGGACCCGTGATGGCATTCTCTGGTNTTCGTCATCCGGTGAAGAGATTGAGCCACCTGA
+
B.2?"B,$*@/9*$H@<4$H9F+?*-#?)/.2*)G<#G48++D"(0?-.:.@%H<2F)3B$
@r5715
TTTTCATTCTTGCGTAGCAATATGCCATCTCTTAAGCTATCTCAGCATTGGTGACCTTG
+
+$)&#!$"#*!"'&"''!+#&#"+!+)***$$&)&&!$%))&$'"+$"!#'*"%$"!*!
@r5716
NGTCCGNGNTANNTCATTCNTTCTNNNNGCCAGTAAGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTNACCCGNAGCGTTAACGGTGATGGTGTGNCCGTGTGAACCAATACTG
+
!*%*))"%#'$"!)'#*!'"$'"$#"$!*%#*$#*+')*#*('%%(*#&#!&!"$)!+!%#")+!$%"!())$&#!*%%$!$"**(!$!*%(!)!&$(#+$&'%+#)$)))+''('#%"&!)*")'++(+*#*+$
@r5717
GGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCC
+
2F1)63H'."%.$&5#=@;=-0AF.4"H8:6<4:A7.84%GF8H5$:H93)
@r5718
TGCGTGTAATTGCGGAGACTTTGCGATGTACTGGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCC
+
;D)+A/(43)H8B+>=,;5=<E*8.&(6#*9B--A9E&*9;DA('DC0+@0$<!4?5(;&.*E=>2C;=3!C57"D)
@r5719
TCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCC
+
$,67&@4F>3:B:!G/99=66(D8"()!.(=:ECH8#DF;$$)&D4%69BG;0(>A#.,(*#H:8F0E8.#!)$29(+%+94B8117A9%ADA;0,(%:,7"20
@r5720
CGGTCGCTCTTCATGGTCCACCTCCGGAGAACAGCCCACCATCACGCATCTGTGTCTGAATTTCATCA
+
#"*#!)!)(*&")*!+***$+)+#%))#(!!%((!#'+)((+#+&$#'*$$+(!&#'(&$$!!'#$$%
@r5721
CGGCATCTGATGCCGTTAACGATTTGCNGAACACACCAGTGTAAGGGATGTTTATGACNAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCA
+
8@6>,$<A61'B7C*H<H(B<!"D-1=#6@-:-!@?#H2>*DEA%?B5ABB-<''078A**H:>.%+)81%C@D>;@BHFG&!&C!EH6&+:'?'CC2CG")0D3H0<<;,6
@r5722
GCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGNAATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATN
+
49'B5;+>2-,H':F2*C)0:7E#'#$2::%H!+B.10(!2%$>!H;G14A!)C1D'*=#%!;>=%6C=6D$E$&;27?C$=##634A';?$+FA5('>+H,6H#&9*@2
@r5723
TACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAANCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTNACCTCAACGGCATTATGGCGGTCCTTCAGGGCG
+
>H4:9-H;;)).FF?=BB&?*&2:)7;6#&23#'(8(&,@H>A"A--GH;&4<%)4=G2;C?!GB';8>0B@)8H7H'0"@2DC*<=2(&D329<7@;6C-AD3)*2EE<&,4(,<,DA".D&2$FE?%#H1(*%-3F"E+.42&1
@r5724
TGCCACCGGCGGTTATGTCGGTACACCGGGCNGCATGGCATACA
+
'%*++%"+(*#+*)*)$"###""()*#+#)(&!%!#&!#(&%)*
@r5725
TAGCCATACCNCGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCT
+
*$+%%#&"**'!#&)$*($$&"*(#")%"&)!*#"*%*"#$"+*#!&&#!('$%"
@r5726
GNNACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGA
+
'"')+"&(+')$$%#!!#"$$$*(+%+!*"()&"*$+#$'%"*++&"*"##+!!+"+!$)#*#%%#&%"
@r5727
TTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGANTACCAACATATCCGGTGTCACGGTGGTGTTCCG
+
B"4#>+@F7/&33*:,%'.-7D,D502'17A$8$@C.%'8>ECC-0)H.8=A4DE71)H;0!A@,:.70@=?EA%GE7#AGB10C()7A5.';#29&G?665/
@r5728
TTAAGCTCGACAGGTCAGTTATTTACNTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAG
+
:5$H00<@?&(B16/>?H48(BC'):4!!)G<);H>1,96B3A1A?#'C8?*:6=569F<-B4*52"
@r5729
TGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCNGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACANCGCCTCCCGTTATTGTATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCA
+
,6:%F940-69/-!'(0":2?E1C(*<(*?64(/H9'1:;;C2H-$F+3A62'A*:'=#7&*A*<(6%D5%2GA9&-@6!G5+/:8D;B%F@"//0A'%*@&)E$-F?>,5D3)&A"60-=+(&<,7.&-H-9"902C:3<1@+)
@r5730
TGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATAGCTCAGTGGCGTGGAGTTCAGGTAT
+
"1"H'1%<1'<&<B/<=#G59D>C/9GDG($G$*<//.$D/;:*,(&!H)2=F1)FFF#<2<4C;%*C84
@r5731
ACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTNCTGC
+
3<&H;,>*;@C(01;&,;#;&;<40F9A#'3A+&G43$4C*90F>?BFF="
@r5732
GGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAANAAAAGATTATTCGTCAGAGAATTCTCTAGGCGNATCCT
+
14G+@71+)=F1G$,B+A$3%4H;-@5G5/;D=8-H4*@A=7=!%+H2$!<::,E"9?!)#@/&=1!*;92#-/D45.4$4#.C-:2%*D!DH#<@8A3F9..2/,52BCF(56,*583
@r5733
AGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCCGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAA
+
3>#3'8#!<</!.6DG?<*'(E,=9&04&1)77D1*C&E4@D%%'=@,$289@+!*9>/#('"%"$*><,,>F?8GAG5E(.">A0@,8'H5"3("?%HBF)F%4A#83
@r5734
AACAGTGGGTNATCCAAAAGGAAGCAGAAAGCTAAATATGNAAAACTACAATAC
+
:4/69)9G(F)!<*=:41;#AG-%AFHD53C?0):/,=,7A7A=2(5.2D11C)
@r5735
TTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCANAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTTTTCCGGATC
+
+;=9DF/-1E!@2444<C786&$G*%@+9<"?@3:11''CH:,%/;:2AF+B-=*-78&A!3E;??#''9!'D1#F6$7>$%%1(+D3-#6
@r5736
AAGGTTTGGACGATTCAAGCGANGCAANGGATGCAAGCTGC
+
*$"$%!$&('$"%(**#$$*%'&*%)*#+""!"%'*$(('%
@r5737
GTAAANAGATTGGGCGTTATCNATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACNAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCC
+
$*+&*(!&%&(+&)#(#+$"!")!"("$!$)$+'&"$+%*$*'(+()#*&#+#+%#('*&(&&'*""'!"$$*(*"%$(%*&*)+%"*''#%#&++")'(**#!++"%+!&&)+%#*(()$'+$""%"##)%'&##*+$%(('&+#$''*)"
@r5738
AANTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTA
+
35.H4B.(0H",B@!HC'@7AB)H?,?0HF/=/>(1#,,=@?0?*F?'3E<'
@r5739
ATGAAGGTAATTTCTTTTGTCCAAGTNTGACTAACTTTTTTATACCAATGTT
+
38'$B3D!8=>#">=HF&7H#?@/AA7"C:)<(D4CG+9$7E=;@F%-18';
@r5740
GNGTTANGCTNTNNAATCATTTGGTTAGGAANGCGGATGTTGCGGGTTGTTGTTCTGCGG
+
)&%*(((*&&#%!"+#$#&$%'!#)&#("!")!!(#(+#$"'!"$&*+*!$##&!"$#("
@r5741
CCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGA
+
G17=#!GA6F0)H4&#'2B?@19$,'.6F!B@/E:)+$7*+,(''"#>>7H
@r5742
TATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCNGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCANCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAANGTGATATACCGGAATGTTTTAAAATGCAGGT
+
,CBE06$24?%=1":H/5+=D143G=&%>:7(7-(A5#:>D(+B3*&+B.H*>B*.6).?E":2E29B8F4D1:5$?0,,DH+5;7.7>=%'0A>6,FH@(3E76D'1&:F6'<C%@>8?@-0?GD&#>50H9"DH-+=@2!)FHF9>D1,HG-*);-:BB:F),.%=CD:H922FD(<(7DE&B6'<;00;+8?$*&.(/.!+-;G
@r5743
CAGGCACACCGCGCCGGGCTGTGGCTGAGAANTGCTGGAAACGCAGACCGTGNATTTCAGCGTCGGCGCAGAANGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGAC
+
#HA.;%"0<':+;9EH,<=;0@B393'!-9A3#:=<E9;@&=+)A3.!%6/FG3E*<#=B:)C+&#%54)@31@H:"?@7&0)+:'4,70,0#1*1H@'E=(4>&@3F@#%E20B8H9H6%>%EA)H;@0'A73<37/"A"@(;6773/.!%>A=GA&E8&>):(7=%+D'
@r5744
GACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTNGCTTTTCNGGAAAACGGGATCACCACGATGGAACAGGTTNACGCAGGAATG
+
+)%"")$('#')'*%$$)'(*%)**!(!*'++''#&"!')")'$($!#%%))*$)$!!#"$%#(*&%+&"++!"&$)+')+($!!%&'#%'!*
@r5745
NAAGCCGGNGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGT
+
#*+>!;9).,"@).(&/9>:..'$>E"B,3:"HA2F,,8B)7(*/9
@r5746
CTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCAGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGNAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATG
+
.#-%%18?"41+<H4?*@F42.C)6/.BC<9'>8"7;&>>9A1,!<F86BF-':!848;B:G,##C-*6/G(&'B>1#+H'%C3-!0:@3+32=6.:B!514'G?4C=$.$070=)=(1@'%'3,&1"7<(2<7>,-&"1@C<4;E@/$?<;#G*G*&,B6-.2(*679A/A"20H!3$,E4H&"/?%%%.B4;-=&'B5"@+"!2)/-*F;<
@r5747
TCAGGGGCATTATTCACCACAAACTCATACATNCCAGACAGCCGATACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTC
+
3)3>1891!EC%0#..=10FF(*=A-95:H4G/31DBDG/+!:H%A7!!0A&99?4<%D,GF7:"@7<=<3%,;/2?:D8&#A"G230H6#@/D$+0>8#5
@r5748
NATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGCAAG
+
!5%F<&(2&D66=;<(H+26@G@,D94)3?5H5+*-HE@A-38&13;%.<@@B->(-;,%.0*9";-EA/&2F*9A9E?2HG!14"E&(+-<5-BG+/)5A:)0>1
@r5749
GCTCGGCTCTAGGANNCGANAGTGCGTNCCNTAACAATATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGNCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCATTGCTGNTTGCTGTTCTTGAATGNGGGGTCGTTGA
+
!)#"'"%*(*)()("#(%(#&(')$')"!*)+'$($+)'#+'$%)$!*#'$'#*&((%$%$'&*$"))$("!+*+*''&$")$+!(+#$+&+%****"$!'*+*#(("'%#&*$!+#+!''&!!#*")%*))$+#')'($)++%!"+#(*"!!*!+!"$#!'++$()!&
@r5750
CAATCNCCGATAAACCCGCCAGCGGTCGTGCTGTATTGTC
+
&%')'&*""%!'+$$#*"+$&%!)'$$!#%&%!#!(*+%$
@r5751
TACCAGGACTATCCGTATGACGACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGNAATCGGAATGCAT
+
:=2H"@???&->(;AF$?%G(82@(66;,&('?$3&;'4A+$+F.:8/;"E=7"8"A=C/:GBF?C)+'4*!?+-'#"%9D5,35E05(!=7(++-
@r5752
ACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACAGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGTCCTCGTAATTAANTGAATTTACAATATCGTCCTGTTCGGAGGGAAGCACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGT
+
*,:F-!CED5/DEC@F9(,4.E&&?D6$1@9@BCH>';E8:11#+E90D+4<)G?$@G+#47H)98?$(++;C&:FA"H;1298#!2E5C*,;8/#A3<225+D0>!98<HE:.E@1G7%C7?38@20AC(B:H1)6B"!>7BE<>$."/@E%4+@HH;C=<1H,(<1)H-&2#G+<%,',7D<H8C=#
@r5753
CNGNNCNTATNGNNTTNCCGNNNTGNNNNTNGNNCTGTAANCNCNTNATTGCACNNNCNNAGTGTTGCGATNNANCCNTNNNCCGCGNNCNNCAACACNNCNTANAACNGG
+
!!"#!$$"##$"""##!#$$!!##$$$$$""""#"#$"#!!$!#!$!$##$$$!""#!""#$#$!!#"##"#####"$"""#!"!$#$"$""#$#"""!"!#$!!"$"!!$
@r5754
TGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCA
+
,3#-H)F>+H>0=E#DG%,D=<<D>5C,";+A:%&!F4'HF/:F+1
@r5755
AGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTCCCGCTGTTTTTTTCG
+
C>.6G&$G#G&1)EFE9".:/G856+=,ECAA3!!A//:(>D"55,A-$05;)8)6304/$F0E8&@,&%BC&=;+C4%26.$BG0<,%G>,&4G7(>FC=HB"9'>5B?!>E2G6$GG"(.8-(1=C<2B#6=DC1,0;<)5;?$20D&*F>;=<.2?&)+A1:")580)89(B+>E2($936=@=<:0==G@-AE=/8D.1,AA!2/3*"9..D0019;*E0#!F>B%B(4,%%5-(>9?1=F3&A.-*76B>#/"B;&B.%;F!-,61B?H)&3AG3+B/F1-(D";CH;H#
@r5756
CAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAG
+
)&*+("$#%!"%)$%!#'*)++(""'+"#$%%)+*()")(&$+$
@r5757
TCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCACAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGC
+
<7)31"*)?>&!;<E);;1E6:DF0-&#A%B0;-(E#.?.!:HG*&<@)BBE4D4C%($6:?"B3=0;C:&G?@9=0FG3;!1?=>$38C"H
@r5758
TTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAG
+
<F*:>F!#&F%@/408,D?B*H86'$'0E<9%;@:/9&6%8>#F:0A7!7G"+HDH8='.(;?,/=$6*<>C6/#
@r5759
TCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATACCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAAT
+
G,0A<H$.="H-1=>('4*07=@!98G77#@*)(>?<(7,2>FB8C+4GE)H454;@GA,)H5)$/)F-G)3HH,@H>3D7"3&9<>'84$D9=,5/>8*$;F@/0ED)'3!E'5*#5@:&@=:*=*"<1?&6'=0%)#=.*.134F%1(H.$2!H.#?<.C-*-'"H.%$%G)=#-@"&8EC0''9"(GH,1"B+3G/44&DB%!8*H"
@r5760
GTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTCGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCNTCCCCCTGTT
+
)DG=-"4%7D#1+F9H.*6(8+71!/;D6&!6),3D5,+?$=?**0<*";0:/"&&$,*H;%/6;@<HB&8A977.6*A$6C.6C15BB.$ABC59&E&(#2+!/0%24+,#7)0"'0.-5DC;6.5<66%.7)9="B;5FFA0E"&EE+(B*%,*HB75A8-C45GE&.9G.)55!$&@+AE",=6>=>G15F5,31)<'!8%#B
@r5761
GCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGATTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCNTGTCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATNCATAACNTCGTCTTTGGTGGTTCCCCT
+
:F=+@,,6G%!20!@$H5++A:@<6@H&86-16G,?=)-2C39%&D%H@=7A>3/H3+%#EF3<-;=/(6E!FDC+C*-2(#,5:EA>!H/<#+-D()##2&<1717E,';9'<.4<,!8%.:7@;<(2FA<9A;#9(@,%$$9D>9>.!,+>%=B);)1!5BC#&DH<D;;@';B0B1</>%)$C+&G&(A'0D7#'):H)?%;H:64#+&&'!-C@D?088#G<)'$4:"='D;D0?$>
@r5762
TTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGA
+
%)**($++%$"($&*#"$+'($'$(%%+()#'"+*%%)+%$#$)+%#%%**&$!"!+
@r5763
CAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGNCAGAGGTAACTTTGCCGGANAGG
+
E,,?40?)%FBB#39426:2=?=<DA.G7!!90')6C00&'#4!;8&4=*G/?HA<,6-"?=F%2H
@r5764
TGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACCGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTT
+
4+"*+<&B.<$$F$0,C4#/A0A5<4&!F@=8E?HF02@A;./?,2H@#)#-#/%BFA&%*9%/BH<21D*D4(*#"@;&5!D4?+C8D!=7.4/=-*<1!HE(G)('%,)6B3.5D.$>')$*#F6>G-9H>3'
@r5765
TGAAGANAATNCCAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAAC
+
!)##&#)$#"%!+!!#%%($")$&)!+&%%&!*&%*)&+**"(**'+)&"&"*+$%&)!)'"'#!*!(++!%%$%%)!&#%+*#$'('(*)')($"!!!&'$$(##%+&&$#()*!')'#""!+&#'('"!'$)##"!)(&(%+'$)!($)'*%(&$
@r5766
CAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGG
+
.8F2*5,,H2CA=1;'>6+#?&.$='F9;/=8#8-&5/<=*F!;+D=2<@1(.%>6!/@-46)$=9?C7%*<D-2
@r5767
CGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTCGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATA
+
%GB#C<=*':#)%!0)1)*G75D5?<4.>C2;6+-$6F:F)<...2BG")9;*!C)*+%E%DH#8-5)?!4>:=#F57C/H1>%2A;85/*;"12&H06'B1%97>F68()G0%A<H'<C#B2H9$9<&@"':2$0.+0/;3!A>.=B;E"1'C17E;3'!F#2%:9!+*E8?'D>H479$4G8B&&
@r5768
CCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCG
+
E=@9;H/*+-CEAD3?::!'9>*4H@'2!;7+&E/6/9A!#7!=<&<C.22=#;9
@r5769
ATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTNTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGNTGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTG
+
12F$7:.#7:8#&2-/-E=F,)E3243$9"-G28?<49?HF:$E391)%=-DD?C'")3F=9('5+9@(?6B3&+5=G#=C6*-E803B.6,"+2.(F?H&6G##6H.-4%$9<".7-H5>*:".+$--43=#$8!.BD9%A*2:=(1E?C:)9?+<9%F%B@<+8C?>%H<@F2GH;#C051:!,
@r5770
NTACCTTCATATTTAACTGNATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATNATTACNTGCCTTAGCTATAATNTATGGCAGAATGTATAACTGC
+
$E;E>#F,@17,F'<,$;G4"=?*416:"B7?1'$<4#.&1<G&(*.0+3",D")H/?B&6+A4C(.C7#><@*3BHF2623D&11;.D*<1)&G/#G.',4%F$E/2+E6*!3)D($)+44+
@r5771
GTTTCTTTTTTGTGNTCATACNTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTAT
+
0*,,9"//@8</*;.69F/!)--&*1,A'&,51*<-A:$D=@)/B=0;6.E@')0$%>6A*+7%!31E1+9:1=/F)-/(:("D#>CB374C1"!2E;-00A-=:2-E3%3AC'&72<H1.4+80"2#.GE6,-3(1E6&1.AB--(8559
@r5772
AGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTNACAGGCTGCGGCATTTTNTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACAGCCGTTGAATGGGCGGATGCTAAATTTACTAGCTCCC
+
0<&9,+<71E/B"B%7,694,<=E?$#?)"=A&B(<7!,:F=7CB;2(=234:((.>#:$CEE7/':!89;E!=7(9,=<<(%;80.>&:!HC?$H52&F*.DH-1;'3C.:-BH)$9@30&"77.(;G62D=2*@F>26++G<'=/C#"?D1)E=*F,:6E
@r5773
AGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCNTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGC
+
6+;8.#0;H>444#E,AD!!5&1AB3;B"2/-:0>C#*&.74@&>5F35-@+#?>'6)G6H$@;$)F-'%1%D/
@r5774
TAGNTNGNCGNCNANTNNACNCNANNCNNGCGCNNANNANNTCNAAAGCACNNCNNTCCGTGNCNNNANTNTGCGGNCTCTNCCTGTANNCCGNNCNCTNNGNNN
+
$!"!#$#!$""$#$!#!"#$!"!$!$$##"""$!"""#$#!!"#$#$"##$"##$!"#!#"#$$!!"$###$!$#""!$$##$#$#!#"!$$""$$!"$$#$"$!
@r5775
CAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACNGTACTCAANCATCGGGTTGAGTATCTTACTGTTT
+
08BF2")-/B.'5=#;&279C1CF3.8,74E)#+E".9*2;>1=6E8!HC&/AH6(GC2@(7E4G#F=G$
@r5776
ATGCTAGATGCTGATATATTTTAGAGGNGATAAAATTAACTGCTTAACTGTCAATGT
+
+&!+'%!!"($!+++**'%"$"*)"')&*$"'"#"'%+!)+++%#+*&(!'""*+)$
@r5777
NAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACNGCACACACATGTNGCGGTGGTTACGTCCGTCANGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCNTCACCATGTCAAACATCCACTCTGCTGCGGTCAGGTCTTCTGCTGACCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGGTCGNTTTCTAGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGACTA
+
!%%++#%&$%"$$("+#("+!(*(%(#!(%)$**#&)(!)'+%'(&&%$$+*%%"+'!*'("$#$!!!&)#$$%(+$'!!$(%)*!('(*'+#$!#(!!*!*'&$+*+(*!)$!*$+&))#!##''&$((%+!%'%!%%**%+*+%'+#&!'')&!"(&(#(+*$+$#%&(#+(('$%%((#(")''*#"!%%"'&('$#+%*+##*)'(!&$*)&'('!+)$##(('$*(&$#))+"("&##&((!#'""'#*#*)+'(%!*&"+")%+)%$#(#'"'++&'#!+($*+"*$!!"#!###(!&'(&"#'!*"'$
@r5778
ACNTGGTGCACTGTTTATGCCAACGATATAGTCTATCAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGCTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCG
+
%)&*'+")%$!(+%$+$'$''!)'$*(&('$)!"!"(*+!#+"$#&'#**++$#($$%*+!(##+&)&(%))%'&#("*"!$!$!%%+&($'%($())$#+*&)("$)+)!*')!)%!#(!%(!)*&&#$
@r5779
TCATGGGCTGTTAATCATTACCGTGATAACGCCATTANCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACAT
+
,4-A&*9@D1C3F-3C242%+5;9G#8;%7+"%4*FA?E#.E!G.!5@915!81AG3)>#?-<&.>,'@24'+#>+D@"FE#?!56&F7'2;@CF7>=?E6,*#
@r5780
GATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTANGATACTGCTCCTCCCCGCATTGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGNCTGCACGCTCAATCTGACAGG
+
B."C4!,D$65&E<:5*-@&)-BF')F873@E0!F6'*BB<=10F=>!49.,4G*9.<#9&F(.<B.E5<1GH@BEBG?H0,@6,&C*:D#$:79),,DF<&#HA(H7?)#A(*.D-0:@61D19$GA>5=($:=HG1D3D</EGC%3%G)&!93<)H=,*"69+:5*1-.A>7?8B>6);A;9<A6C$#GA.(!E=!C2+50,61?C:(+"B/+2BF@7(2*E$*>!=?*/0(2;?3#2'<F965--;C-:/3>,E'5G%.B@G&H*@;.0635=2
@r5781
NGANANGANNNTTANCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCC
+
$)($*'()#&**#)$'+#+"'*)'*")'"!**'$!##%#(+(!&%##**$"+!&
@r5782
CATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACAT
+
=<?C=7&)H-:BC:FH0(#%"1?1C-4A="/%:#3C&3).0)6+=?A63G&'.'AA<B<;)6'6:42.F7-)@GE.$<AE&-%06%6:!0,-3;>6!9H=/4&62$$/.$1"B"@4078*>!A(6#+5;G/@<").4)7D-
@r5783
TGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGNAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAG
+
>-8'3E(GE;*6F/;70%7.@>:AA<137A+C/014>;5',B+":2%)E?38?1'2;00/34-#-!/"/=4H5=43?(/'9=77E4AB8F+%5&C$08E:+7(=HFBC0'7##1#)&8.A"/#;50#E,2=.'ADDC!,1(.F.07"(7G?@+=/"A6-.CGE(7?F.<F5.
@r5784
NCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGNGGCGTGGAGACACGCTGACCAT
+
%+)$!*)*+!")(()#$###$%&+#!"+'*+#)'&*#&#*'"+#''*()++#*&"&)#+)#!%"&#)
@r5785
TGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCG
+
3C7$+G@0D;-@)7%,0B"0!(5HD02-1&6G*"C52!@*CAG*,
@r5786
CGGCGAGCTGCAGCACCATATTCCTGAACCACTGAGCAAACGAGAGAGGTA
+
%D64;<6G8#0G4$5=D55/G(7>262A>:#0:@177)F</+H<,+>?+.G
@r5787
NGNNGCCGGNGNNNNACTTGCGGTTGCTGCTGACCAGACCAG
+
%#"#(&')#"#$!#!((%$++$')$!)%+"#%)'""($*%#)
@r5788
GGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCNTCTCTGGAGTGCGACAG
+
F&A?F+$$FB@B%$&:#EE-C7G;HH6=)@FHH-H2=E.>$F54%*>*2?0952+,F-0A/
@r5789
GGAAANTTTTACCTGGNTATCGCCGGGAGGGGAATATCAGAAGTGG
+
7:'=D%"'94?(C78EAAB@8>B:*F(DG@(F;G.@(2;?%+.+*A
@r5790
CNNTGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAANCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAA
+
&&,@"C4>;1-*:4-8$4"258021=D*A24(784)B<901,(:(A!)!H"@6"C(5*$(=#C+9141(:54!+?/F++8.3'299.001:19;$36'%
@r5791
AGTGTATTTNNCTTTCGTCTCANTTTANCNNCNGNGCTTT
+
($&&$%'&%%)$!&&)'&(($"'$)#*$*'!)!!&++")'
@r5792
CACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGCAGCTGCATATCGAAGTTTTC
+
?9A!,A7$A)5)'?,?BG&;A3C2(&*+:+.43F>&D*<@96F809D2)!AB)=;9?',2?345#A0"17:.&%H,D'1)./H:D#,D1-&+4/HBF=EC%<46/7'C2)%?(#4(C9'117AC8@"*"DA2.-7<C<(>;4EH+>%)
@r5793
TATNGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCATTTGCTCAGTTGTTC
+
C//E'13?65G5H2.1CCBH.$/9+3.!85+2A,.7#G#E@2/"!=27#H+45E;+8$8H7<,H.,0(%"G1#?)2H>.&(4/4!&8#1D6;"8
@r5794
TCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTT
+
F!2H-A#@*'%AB0;0"!D2?=*96"-D4<D*;"14<.'?3,)B+&%)4%0"7-43@E:E@62&&F0G8CGC/8C9G25:-9F5#C6&+8AH*@6>?<<$%9,9;?6/G/?2
@r5795
ATGTTGTGTTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATA
+
H?H2C)?#1BH"#&05C.#/@=/9",4)+B5->E1E3&6@1%%&0D4>18%*9&33
@r5796
CGATAACTTTCCCCACAACGGAAAAACTCTCATTGTATGGGATNATTGG
+
+31>+*986''&3@<,$>9:2H52+(-)G-5<)<1E#&-)E:3=4B(8.
@r5797
ANANGAGNCNGGCCCANCTTGCNNGACNGNNNGTTCNNNTNTCNANNCNGANNTCAATNTGNNGNGANNTGTNATNNATGNATCGNCAGNCNTNGNTGNNNNGATGNTNGGTNNCGAANNCTCNCNACNNNTAGANANCNNGTGNNTGTNTGTNGNNTNTGCANANNNNNGANNANGATGCNCNCCNCTNACCGNAATNCTGNNGTNGNNNCNACNC
+
##"!#!$!##!$#$"$#$#$"##!$$!!""!"$$"!!!"!#!##"""$$!"$$#"$!###$!"""$$!!"$#!$#!#!##"$"#$$""!#""!$##"$"!!!$"#""!$#!$!"###$!""""#!##"#"""$$"###$#!####"!!$""!#!""#$"!!$##"!#$!##$""$"$#$!$!#$"$$"#!"!!"##!#"$!#$!$$!$!!""$#!!!
@r5798
TAGCNNNGNANNTANGNANNTAGTANNAANCTGCACNNNGNATNNCNCGNCAACAGAGNNNTANGGNTCTNNACGCNGCGNNNTNTT
+
$!#$!#!""#$$!!$###"!#$$$#"!!$#"#"#$$"#"$"""#!#$"#!"#""$!!#"##$""!!!$!"##"$"$#!#$"$#""$$
@r5799
AACCGGAAGTTTACTGTGGAAGACNCCATCAGAACCGGCGCGTTTNTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGA
+
7'*@?>8-4@%>3.4?*.=)>/*4&9'3941@>C-!CG6C760;BD<3:1B!:5(12:;?'FF:0,27<A9#6"@D3<(?32=$-+9#"4#32/A6/*!3)$;
@r5800
CTGTTNTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGC
+
'1?5:E*+:0DA)G>$1,"$=FC#+)A.-'</&:)!)BFFG"@:G@85C6A2FH%B8!
@r5801
TTNCCTCCGAACAGGACGATATTGTAAATTCACTTAATTAC
+
:>E&1:,<.E&(.!F.DA($(25+,?5@ACE9?33>$(:,.
@r5802
GTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGTCGAT
+
E'B:%)%@+E7A?B@G6C?5C!,&.99*:7.5-E0E!06C+E2:H6'0684">E"8#E*;2B+!H@*G1&&:7=#<&H1?;D.E'H"B:'+=C!=5.4<&%D@F>6-E;:$%.57?#9+>.G.$!4#G125
@r5803
CTGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACNCGCACCA
+
'')8.'8"28?=,E)BB!3+998B/+6.54++H:H>&@./+7+4-@)1)5&26@@>B(@;5&62.007-@"#D!CGHB
@r5804
TNNANGNNNCANNTGTTNNGANNCTTGTGNTNGNTCNNTATNCAANGCNNNNTATGNGNTNNGTCNNTGNTNTTCGTNT
+
$#"#!""$"##!$!$$$"#$"!#!$$!"$!##$!"!##$$!"#$$!$!!"""!#"$!!##!!$!#!$"""#$$""$$!#
@r5805
CNNGCCTGCTGGTAATCAGCTGTAGCAGGCCTTTTTAGGGAGA
+
)!%)F<>5.4>28+H-&>?E8%9;DH!96'&8G$8C0'1<H?)
@r5806
AGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGA
+
#2410A"GB04HGB5GCD+6(F9+C9"6A7A@@":@."+-'&/G8,#+/698FC%&E,%
@r5807
TNCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACNGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGAC
+
$!>/*=-%5H0*=2D-=&?>-%/051"EFE.F*.9F+8G(&6?,#6&HEA*E$*?A0+.,2<+H,)?3ED,7%F#@5>3'./!F-D**,+2+C)#7!';2D!,G1!!C:3*B::36/GF<8G4'C8.7#('@,)<:$2)$4.F*5:B8G'%-@!@#!"?6?$*B;3(@H&,&1;?H$'F$&,9
@r5808
TNNNCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGG
+
#"!&'#&"%+)((%($&'%$*)#+)#+#()!(')!##+"*!#$%'+
@r5809
TGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCT
+
*,7A;":;A(,,9E2<D88D=HC6DB0&C84=$)!-=,,,&(450?#,=@7A
@r5810
GAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATAC
+
C-$G?9C,6.E#C=*%&G6;,F+F4G1-F53DC6%?$C80+5
@r5811
ACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAGGATATCGACATTTCTGCACCAT
+
%E>)EDBF&5.619:B;3.HH&;=<G,@,9,&,25G/3.A)(*"&*7E$0'CG=98>'D#*27G3<#H**80/.E+89@>))75C4)C:(=&H7#D+'
@r5812
CTTAAAAGCAGAAGTCCAACCCAGATTACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAG
+
3/"3B)13,,B.=GGB>1%-<75*0H#($.?D0*=HEHC2)$<%2/(H"&;-'D<5;G499;1/*'5A;+F>G.3+CA,G
@r5813
CTCGGCTTCATCCTTGTCATAGATNCCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTNTATGACGTAA
+
%028HB9&*)G-D,;'&*)@%?116@2&6.$#.@+5*FG(%B;%A3H3F(66=4FE,H0!C23HB3-#=%FF)A6E"7
@r5814
TATCTTCTTTGCATTCACCGCACCNATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACA
+
/D#+>AF:&:>;D3)D.8>8@:C:!C9@*@3?&":G"F1@,#<6.(.CCA03F02E=F;$=3H<((/*<.-@8+'*7,9.@711D(@.4'?39HG3B5.D(/!,4.
@r5815
TTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTC
+
/+;DAH&86/-5'$,G'4G.&G.4#!66F%D#+G&%@<9'71$:&79&F",>HDEB)2D,='<.);=%8:!9/7=A
@r5816
CGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCGCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGC
+
'@BAC+8(?<#00?+'9+!03>-%.&(=CG?A/%3;#F$!&@"*&6.<15'#>((:+H75*C>+/+7-!;&>2G)#4)?E/!11AGA=:?E,5<8#3'=B@@&89%>5%A9D+"/>G3G<.17C:">-8
@r5817
CGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTG
+
H2A#C@"#4@8G'0!#;5-,$1?$08.(A!1)/:,!<9E"%?;(*+.<:H+?4;)8B3"'261=6>A?-?!4
@r5818
CTGCTGCAGTTAATCGAACAAGACCCGTTAGNAACTATCGACATCATTACGCATCGCTATTACGGGGT
+
(52@"<%9C1'*E0*807F3=8-:CC>,.-@F'*1(?.)$&"C9'>%84D$A.*@5@E$*813,#1*!
@r5819
TTCCNGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATANCTTCCTNCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCG
+
3=9%08/;4!5%(393;A?BCH"A9=4::<=>C)<<0*F.DB@5!9B6/=&<*(*7'2039,$C5<E789'2G<9A#+H;FB5?*39=+/>.!E"48;&E,#-$9&,1"43
@r5820
CATAGTGTTTACATCACGGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTTT
+
+A$55BF-B>7H,<"D$G;E"39..2-0,/F)8/=*964%23DE,5*,*"!!.;29#
@r5821
GCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTNGCTGTTTCAAGCTNAACACG
+
%)G1D:14<+$'.G0"D!=?+.,"*HHD11/G0,D,'#.+52,?4.,G@#?@#G*5!7015(@(*F+23&:&H;BF):!:+..'"/@.'
@r5822
GGACTGCGACCGGGCAGCGGCGGAAATCTGNCGGAGATACCAGCTTCACGNTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCG
+
*'#++"'+*#!%*++*$(((!###+)!))*)&))((#*((#(&*$!(*!(&+%*!!)'+!!$"")#&)&!%%!'*"!%#%$%(#!))!#+!*%)*
@r5823
AGCGGNAACATNTATTATTCAAAAAAACAAAAACCAGATTATANGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAANTGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATA
+
(#*"("+%++'"%''&&&+"")!)%'&("+!&++$))!!$#&!#!)+&%)%&&)'#&+))*'!!)$'''##+%'"&%$&%()$"%&#$($#"$'$'"+&*$&)+)&*+&&%&$!*$)%*#&%(+""&+
@r5824
TCGCAGTAGATGAGGTACACCAAGCNATTCATCCCTATATCGACA
+
3E:3#-;9A-DCA=8"FA;,G#$(;2F0>>=H'>#3E/H(?AD*;
@r5825
NGCGTGACGGTCACACCGTTATGTTCAAATGGTTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCAATACCGGATACAACCGGAATGTTG
+
$D"/125<%D%H:,77?>C6(GE@>A$H'=H;&1,'G;(+A.6":FB>>;3@3AH9%D6!E9C$G)3=#)@/&!%+/:5#5#EE>@10;>9->%(#%;/C8-*&?A39!+:D!0,*;67)#@+:?@(C?&?)!+G
@r5826
NCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGNCATGTCAGAGCAGA
+
%,?);EB=<>9H(712@.04'9%!(,>AD1/%H6D*15?G68?!2C5685+C?C7<88*
@r5827
ACCATTCCCGGCNTTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCAT
+
07"F;H.%74G$*)*&AG-43<CC)..46+7?2@6/%>3<%'=<A2$00%05
@r5828
GTGANTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGA
+
:E=?/"40+EAFC9<&)";6-01;1=1F;.=%A0?30,47/C++'/,*#-<G,HD3HF-,%B/?4;.7,=+5<-//-.+C3!FF.5)17'%#,DH.6<1;?:#+%6$>."8&52-"&.-D$93A0>>%#(!>H60D(C==$2%4@9>#3,D)F4#-2G2C"-C!((F';=&
@r5829
AGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACG
+
*5:5%:?CE+)<D7$9&?,:BD4A<1@''&=:0%F4(.52F$*5"=F2&+20"&-=C*><#,86B6'6/(%FD.7!2&H6+
@r5830
TGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACC
+
=(2+2.59).>+->.5G4!'0&(/*%A"B..,%/1431"-/2,B5#;2#D(GG(6*HB6%,2BG=6;A/)*D>61A.3</DD-FC5#75.H',1DB40&/C/:(;?E34.4><1
@r5831
GNTACCGTGATTAAGAAACAGGCGCTGNGCATCAGCGTGGTCTGAGTGTGTTACNGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTG
+
$$&$#$++"(%&+**"&%!&&+!&("#"'%#!%#%%)!'&)+&!"&%!#&*!$!&(!(#'&'%)*!&%#%+(!&')!"!&)#*(!#!#(#!*"#%""%+(**#+*+#!!*+()($!+**!#&'&!)+)$&*&!+!"&"&)
@r5832
GTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAACCACTTNTTCATNAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGC
+
</6"1)A&/16-9<,/@B8:)<12'G#G6"A=C;=246*B'.=E&.!/*%!*3?H(GF-#5%,802.><&5$*!/F+%+9F+31E0?19E("*8.56;:$,+A/=)97>/;=6(%4$?C:7*9@H+.8.A+",C',7B20:%,8
@r5833
GCGNTGGCNTNNGTGCCCAGCACGAACANTCATGCTTTTAACGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGG
+
$)#")")##'"!#(**'%'*+()"$("+*+!'$)$*#++()('"()!#!)%")"!%#*%$%*'(&"'(%+())'$#+!%!
@r5834
NAAGTCTTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTAT
+
"'03&B2.CE::1)/B:3G8G4(>G39->2HE!(G4-$?+.D!,F5@-G,9C!6.)A;6;106>43*!<;B#/C%8;+
@r5835
ANNAGNGTCGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCNGCTTAATGGC
+
&&*&##!)#+$!(**"%(#+!&(*"))'#('#+$&%*$()%+"$'%+!$"+*%"+!&
@r5836
CNATCGNNANGGCNGGGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTNCCTGANCGCCGGTATCGA
+
"$)#*(!"&$("%')''+#)''*%"%')#!"&"%)(%$('(#%"#+)!*%%)&%+"$"%)+*&'%$!%"'+*!)&)$#"
@r5837
CTGGANGCAGCCCNGTTGCCCAACTNTACCCNTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCA
+
$)!H-2?,&=<D*%.<%@@::?E7B9@8&"D,&0?C'F!D!$015=9:%7)<$?/ADE%2-,.*4B6@'#5(4D47+%4!,%-+>4BC..&54C3:<,
@r5838
ACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTNCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGT
+
.%E%HGB>'7E8<>B=D<%;#4B-5.',!1F)-'#0E,*A6AD$E".*,7"<B3B5((1%)6>5/7BF=5E$#2B86EB)0&*11:*>8-C>1(===;!;2=:*
@r5839
GAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTNCAGAACGCGCCGCNGACGTATGGAGTGC
+
9*)G&2@$H#<"&,4@7?#0A/'BF6C8DHG=87&-32@!AB$24<'=C/:,)5F*CC@*A07''8;9(/+F30:FB;?,
@r5840
GNTGGAANCCNCATTCTGTACTTTCGTGCTGTCGCGGATCGAAGGTGAAATTGCCAGTATTCTCGACGG
+
($'(()*!#$&%$(&++"+&$+(%&!)%*##('+%$"'$'!#"&&!)*'*#+!)&&%'+!*(%'&"'""
@r5841
ATTTATCCNNNGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTANGGTGGCCA
+
$)&'$)&"&%"+$&$(!++"#&+%!*&&%('"$(+!%+')!")*$$*)&&)"$+)%$))*&
@r5842
GGAATGCNTGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTNTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGC
+
/=D>?2!56($F.$;+*1E:8G"F"*EEE8G517.G5B433<5+2!::51;C27@6*+8>CD9>C@3HE4;>3<A:A:9:3G>>("3E%141&#0%>@9*<#2!533!>47HB=E*65B?!92F;6,A@>C/0EG>.+=B2+A76!;3+.?%@C.7"8H5GA</'741'E7;@0F-)'8@)E?*34H;1;?@B/4*=@6%;%C+BG8%$G/=HH/58-))2(>45'@F!.?"1/"
@r5843
CCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGNCGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAG
+
C!E'?8AD8&%$:-7:>%!$5;++9$*2)E5"4C<;%/0A""C@3BH?/;B$"800*A4'H!0$<7+-+4'>8=?)*-4;1A0'<+#6?+&9;'-CA5G)5<@$G(<?H==C!%"$:A,,&-'682#(1*$:'=';'H,)/(9-"0-!74G85CB&ECA$2*CG4D+C6BF!:HH@=D4BC,5!H(2D+9'>@BHDG1%
@r5844
CCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCAC
+
<472A6)D5&8/.,?(7-+../.?-2/;CBA%!'510'7<.G6?5":79
@r5845
GTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCATGATGACGTCATTAAAAACACGCTGCAATCCCTNCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATT
+
&/%'3<>1,=>G'1.!)8H'3.-++.;&2AAF!#.C9(7#>8B&8;:61=08(*#81(5'A>-?A,'A<<+G(;H&@.$>?2!+84FD+E>?/8.)83B%$C0(*(.GC/1;D:C04@?DB0E'8@69,7#$ED6)CCF-5/'/B,"&;14,E%&.3?>-#..&4#
@r5846
CCGTCTGCGATATCGCGGATGAAGCAACGCGGTTAATGGC
+
%,H7-1"DC65&;','!.->8$)38E&#3;:>#7%8>,A8
@r5847
ATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGT
+
@$"F(?*39@G-E@&H2G#?B+1$F<=2,!2"9G=F9-?H
@r5848
GTATTAAAATTAGAGTTGTAGCTTGGCTCTGCTAACACGTTGCTCGTAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGATGGTG
+
,-"-(=5)21+!!#)'<A!#/$":-!,-B$2DA%)!E4;2=F1$D$G/</6/+03H..%%B5)(@1)B1,H$C$4-E=068ED50''))?A0;?+-?2.9C1=>2;1
@r5849
NCNTTTNTNATNCCGGTTAGNTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCNGAGCAAAAAG
+
%"!))#")'&(&*%'"&%$(#''+$)*%!'(!"#$($))$##*+*(%((+!'"'+&#%#)$+(%!+"+"!*!&'*'"*"+(((()"
@r5850
TGNGNACGGGCAAGTCGATGGCGATCGTACTCNATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGG
+
**#'!&*)'"$+%(+*"')$)!%&#'"&)!*$%()&"%'!'*$)#)'"#$(%&*&+$($#%'%(!%#&**")&#')""(&!")+%')!%++'(*+*"%'+%#*%#%+%!$"$!("+"*!%$%#$#&(
@r5851
NTCACAGCCCGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGC
+
$!%'+%*&&+&!!!!+)"%*+#'$(*!(%"!+#"!"&''*'**!+$&
@r5852
CGGATAAACTATTACAACCCCTACNGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTNTCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAANNTGTTAATGAGAGAATCGGTNTTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGNATTTTCGCTAGCAANTA
+
D%%".2HHC-*H"25,9$'@-2;,.3C94(#D<%A/>$#&G6&-H66C<;:F93:99:/>0@87@5$3#29>+5H5##2(FC$0C').22:G=H;"8#A2;C&>!C(B>@G=.##2?8<"5>E%#7&-B,GC,21%A)0/=&GG'EG$5$';E.%<8E(*)#GC7"A8%<)>(?=(:0CA;;+2!)$9+0+)HA!.=@18@8+57*4<8;C4>E!&F$!6#:5;+2:D@FB1/4:
@r5853
TAGTCACCNAAAAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCNGATGAGTTCCATCTTTGAAA
+
(!')("&$&)&$+#!%"'%"##+$!#$&"$$"**$*#(#)+($)!)*+''("$))&((#"*%"("%$)$&$*$)!#%('"&!$(!&(*%%*(!!#!$$($(!"+&'#$"
@r5854
CGNNCCTNAGCAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAA
+
("'"%%#''%"+'#$))$&"&')"("!)%+")%)#!"+'("(&)++$*(")(""*('$%!%$+"(
@r5855
AGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCAT
+
C63=F4&$00*(!G;@*15H9":2/6?+C%=.HF3'H3B,);,,6H7#2B
@r5856
ACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCTTCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTNTCNAGTC
+
*5*6;(*3=@/*';!3&60=A6.D57&1"F.)29/=5-1>H*!$:8*G/60A6*@-!(.2>.;)4F.<;?(;G4%7C!(<#A&E8;03&&7/;22#1!-4
@r5857
TTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCT
+
G>9?.8%2A@C%*B<'2:7DA3H!.4E2B1!B4,@!40?*319=8.!+,79A0.+E:61>@*4')C:>F*!?@0&.7G&&F.B><BC@C=)9,()?;@(;;)$)9CB<#$7C/4,&D>D"D'/.82G9"4>.*390,=E,<C&92'<!-3@#&>03.'E>.
@r5858
CCGACATAACCGCCGGTGGCAGCCGCGCANCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCTTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCCTA
+
+%(*()(+"%"%%'&%"(!*&#(!$++&%(")*(*+)$+#*'&*%()+*%&'+!"%*!*(!&!!(()%(&%"%))"#)&"!&'!#('!&!"!*+""**(((#(!#$!&+$$!!"!"!%((!$+&)++*!+*'%$+
@r5859
GAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGNGTGTAATTGCGGAGACTTTTCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGNGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGNCGAAGTCATGAGCGCCGGGATTTAC
+
F#F:2#+<>@&E2*;?:%4?>/>B#D-*%!C.(;E61>0=%-;(&!*'7#*<C5>A#?2!#::+=.!A0;#$/6*;)G/#HGG=D1.=1511"$$H$$BD&!<,9F>#$'D')#>FH)+/'51(<//7@(E.494D''@9E@@5DB'EE10-$>9.9'48DFB6%G*&F:F6/038$H50G!"!G62>:@DA8*A86=#*/5#&C-*#5@2A&G!9*;199+%7(<&6A-(*2%%=9F!7''>F67:$0,A.)<-;C?(64">FF4%&H!C+9H"$CF!C:..E3?4D$4%-'.3():878<#%/*3:,7;H,<H?-4=+4H'@015&GEH3G@?+@(""3H,;6?C-=$-6;>E:'-%#-EDD??+#1;/):.=2B$"G?H6B/9@6=&-$/:G#7?"H9,=,&-/7;#9;:/
@r5860
GGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAG
+
%<HF@9A%GD3C">):#5+&3*(4#<@E29-,2+2671F"9
@r5861
CAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGA
+
.595*.<.G=('6<B(G2#7A0%G8(7D>E/9:0F%@!758+1,+186'#"C2>,3H)
@r5862
TGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATNCCAGTGAGAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGACGACA
+
@!/-E<C(F&4D6*B;;&9AH3.E5F7A43&<3*4+09!$##53E<D)5.8:)'",$FFEB%;$;3/1++=B7A#-,A388EE(*>:@0/5,:-(.AE9&/2D!?(31&E&-2C6-AC@F@!:=AG2AG1'$A##%GFHHAA9,94@'E#
@r5863
NGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCNGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGA
+
#8>&H%;/B*+B!6(4.*G9++,H.!?C7H3-#H(7&B'>#)&H/4>"(G=1*/DF<.5,C/3*6G.61,?G*H=3=1@8)2<7F115;&!,H:FA'1?(8GG.'-?2*%>!1&.57(89D7<H:E,.B#C?%G%/FH2GG8$G:C:49A</9=!7;=72;:E=#&DC$09!;B11+-CD#AB$&51&209%-C:07.=6C/,F88B8DH)5+*4:D)&$H51517'-*.(GG$#"*C/9%4&='!(!,,;C@=#56!2C
@r5864
TATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGC
+
/6'4?,9!C::>0/+4%+E5A&.7'?!*92)"C37=46#6>4$($5&4?.A(H#)0=51
@r5865
ATGTCNTTACCTATGAAATGTGAGGACGCTATGNCTGNACCAAATCCTA
+
.;F?!,FEGG@$?*%?"7*A66-.(:$F=/7'>(3HA(1)+CFC''&//
@r5866
CATCGTCGTGTATTNCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGA
+
G:3,$#!1%8)9,69153*95'AD)5(61"=<77>@HA*&D%57F)GA/#C:!5!5854F,)(0'<$8&=.=61;%$22?637,71->B'B$6@"*H98%79%'8AF$$@/3<>?9;1!,>1;*B?81"4+
@r5867
TTCGCCCGACCTACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTNTGATA
+
!')$%#"*"'&!+(#%"$''+!*%!!!"!&"!*)+(!"!)$$%"+%"%%()"('$*&(&##+!*%*+!'$&!)+)#+')&!!"+&$#+"%
@r5868
AGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTG
+
3.:'.8C<%6?<(,"4EB'7,$-26'E83G'.*799>-'2)9<">@!$?$,//,7A%?<1B&D'-<"B19C40<%!EE@CD2&!1)"8%:($#<*!G'A6HB=$0>4!6:+%EA..C83CC/$?"4#3#9.<%'%7A"B:-!C9747'))-467=H784C!!&H?
@r5869
GGNTCCGGACNCCANGACATNTCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTG
+
')&$($(('$&$"%!%*%()!!))+(+)*$)'#*'+&&)%+!+)%"!$+'('#!")++(!'+&)+&%&(!%!"!**&$+#&+)&%!)')'!'%%'++"!+("!#((!"*#")*'+(&&
@r5870
GGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTNCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGC
+
:&C134:@"7&>;'(D+,$764576+'.5:45$:62(="!(H(.$(##"8&+EE;0="(&*A$C68*B*$64)FH)/E6?%,'F.!!$5%("H!%?<7<:DH-DE86><&*68!-"F1?F:%6967&A5H&$"A-/@$3;#-8(>#'.*%'=#B1?DB.85,*<:9E*6<B*5F7A/)9=3?)B@8FD5?A*7A+($;G
@r5871
GCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTNACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGT
+
94+@="-*3F1=?46#*(HG.8)5&5*)$?=1*<A86@.G!@;GH6#A7:C9#)0?9#*C35FD!'92,.C@'")5A,:-1(6(:5
@r5872
NCATGGCNTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCC
+
#2)"<"0$)$::4*8G+@AF*.*8G1,4#-H1<G"%<CC?,(>('<HC#&D9F6F><2:.2;$#(D9;"-!!(*>DB>*!/<8-5E/D&$"1;H-7>?*;6<C)=:>%E65&-/56*9C(1,=-!"
@r5873
TCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGNGGACTTCCGACGGATGGNCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCNTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGANGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTNAACAAAAAGCAGCTGNCTGACATTTTCGGTGC
+
#*0BH8F(:;.H6&#08$:!;(HH#3(5<H>03/*>G/4&#%;0;E>F$:@&%)+>3C/D9'$-'2,1+=?+?C49*E/G+;+,)$EF+H,7=F&#8F>)*9E0*118#62$%</>0&<AC&)E68;%A;<<=F81<*=DA@56:4F1>,86,)2GB,+C82=7D(.;A.*+%3@F)-6:9B+<04$##7$9=*@-?G'*3;:02-"F(#,&#'<HG=.':EG+7F+AC475-D#''B!<<C#??7<0*8,GH20&/5*.033:/H'+0-'9!;*<<$<32A0+1
@r5874
GGTNAANCNGNNNGANATCCGCNAAGGNGGATGCTTCACNACTNNNGAGNGCNCGCTCNNNGNNCNNNNNTNTAATNANTCNCGNCCNNNNNNTNGNNACANGTTNATGCTTNNGGNNGA
+
"##"##!#!#!##$!!#"""""""#!"!##"$#!$"""$##!##!###""$!!$$#$!""####$#$#"#$!"!""!$!!!#"##$#"##!!####!"$"##""#$$#$""$!$!#!#$"
@r5875
GAAATCTGNTTCGGTNTCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGNCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACNTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACA
+
$)#&*($#$"(%$%#'++*)#%$+&"+#!*(#+'"#""%+#+)%%%%)"%++!(+*+&&!'$&(#)%)!)&#"%*"*"""%(#+&"!%'(&!!'&(+$#)($$()+'$++$#()"&(!)"#'$)"+%+$$&'&'!#$+')$'&(($&"%*$#+'"'"&%')+'###+!+%%)$%&'&''"*"!!%"+*(+*!$!!($(+*&#%!%#$"""$&*)%(*#+"&*$*"+%&*)%#
@r5876
CGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCA
+
G,<!7&C<6&>!$>65/7FB=138(88!%8:E2DF=25CBF.DCF(H@FB<#>B8;G'H?!%+,4@
@r5877
CAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACANGCCACCGGCC
+
C-7G;19/;@7B9"EC+;9B829&H"/=;"$.;@$#'!,+3BEG7":9'%)$
@r5878
NCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGG
+
!1%!G*B4C(+F%#4(*=*?B-7C#<4CB*C=&+(..A&"F?#@$;)89$5*B"*H-@D.>3&'D87
@r5879
CCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTAC
+
HC2)341F/-@&?80-C:,<$"%/F5G6-H+"G2883:72%,G?7<F5!'=@G8H3)8'"7#B1;=<=='/4CD
@r5880
CTGGCAGCTGGATCTCAGTNCGCTGCTNGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACANTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACNGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCAT
+
"E$&E$F:H)9,)<H4#A;822?HFC)47,8=HF&/5F23#;,8#)&4@F81!H(1GA=%8'&B?8H.?*791(37.(#37956:50*G?7)?@B,A5HG;&#.#&:EBD-@+.+89F8C,"1$"D:E>*C"BD5,4<F0"#C>B+@;#,,*4*-C
@r5881
TGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCNGAGAAATCTACGAGANGTATGAAGCGGTTGGTATG
+
7A@31B72%>FB77:-%9>98AHG2108,23$E/>612E&E5.#19011&EFGDGH>C@;6GE%0%9D8&418>+(@2=C7'#(DE@':E;3<2$--9=#,=6;83).&7,)C<=F#-F)>%'G.0#5:H/F$+940G*H/G;D>)7AE;!@"*DA/36'2
@r5882
TTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCT
+
83,+/FH=/:3AH1!(-<!#$&/"2?/8$!?6/@,>A&G/0
@r5883
NCATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTNGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGC
+
$&?65*307DB(6&#+*2F)";C%E!>.*>7=C/>%?H&G;2">0$:F<G8>=>3ED12F2<=:.24:4*"2-$=3G*/21?CC)4;3<%'8F*&;5-!=F:CE(,-!,G@/:4*=/(@:1FA),A-9C4#DF,
@r5884
GCGCCCAGCTCTGAGCCTCNAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAAC
+
)'/;DH=93;,=)G@B+!F:'&$&C-169F&*E;:)61F7=(?0E*?G=!?'7/%%F2)A-+5"@?(G*(;,/3-!(*#D(6;<@%28:&/>?4D=!8702.H''1#(C<,,
@r5885
CTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTAGTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACNAAAGGAAACCATCCCCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAANAGAAACCCAGCAAACATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGNAAGCGCGTGTGTATTGATCACAATAATTGCATGAGTT
+
0=*HD4@#'70?F9?A>#H4!A1:)56B=*H60-GH):?*&%5)$0&*7&3$(*513$:)(*=/)E@*,2)*5B)-,,H'%5*D0>(>;">89D;:-2<55(0@$8C=@$*)@2>:/'6H>%E1E,>+>+88F+07-D7/9A'8>+9,;"-#E90EA".-1.H:AC9.,7)9E*+':*C##<)+1C,88$/!*DF2=%2%)0#F0&>=!F319#-3%EB7"'70%/)CH'-%->=:E%0'+%6?65>/<.3)!?EB<=C)A1'>4#0;F8&8+$&"9,*FB1)+E202.@#G5A*.$,<C0F<<9A0#2&!FF'*-?>EF90"'42&F8+B2$E(C:5
@r5886
ATGGTCATCACAGTATTTGGNGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGNGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCANACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATANGGTGAGCGGT
+
03GG*,<()6C92!GB@C3@%C?++>:+(.($BG>$H@5*?)E!0;<6H8;24**.-E1/>GD.6/+/#!-6(>;G<'9&A*%'=+5#(>3.@7#A-,7?B&8?>(C45F88<14*))05H8G8+E9!5C#E;94*61:1>BF0*456??@8@DD99+&!$*1GF4HG#G:7AB:;929BA>@<)D-7"!>8!<=:21?+*4"?!H#H=6E
@r5887
CNCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTANTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCCC
+
$$(+"'!&*$*"$&"%)#!''*%(%''*)'&*($(*")#'*"%)*+$"$!!%+*(+++*)!%#+!)&&!&("#()*)*%(('('!$!!%'#&%'"
@r5888
TCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTATTGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGC
+
F<;8!8&':1G<GD/5&#.;%*.<F:'@5H%,*0B33H;*-&8#7.+=6;<>))CG>GB6=7A3$2?(D3)5.*!7)A*.?()03,H
@r5889
CAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCANTCC
+
84+1;$+'B%@B=A$7BH<"+"F65;*/!A&"4788%HE3GD</7,/95D<%(:8>DA@2>;4H1+7="0*!9
@r5890
ATGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATANCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGC
+
*"+$'(!'"*$'*#'''*)*'"#'##"'(%)#)"(*'+%+((##'%+()$)$)!$#((#"%+!)$'!*%&&(%+'&'%%#!#+&'$")(%(&'&'!#*!)'"%((
@r5891
TGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCCGCTGCAGGTGCAGAGNGAT
+
4=;8!+,-=&$%A95"D3G)2:-D;-")CEA*-=5H0,@=D>$8A+7=:7GA7FF99<D5,CA@.*,1H2'&?E?(5D!C6$;*%'??G.5>@02#A11@5+'7&-8D/@&.E$;EC15)HC
@r5892
NCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATG
+
"/#$@A&59,%&:*H2,2/!$#?:H&)/#>EF8$)<A+@$
@r5893
CAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTT
+
48ACG1FB<.%970A,$?7+0H!<$,=-:/:$(1*./02!
@r5894
CATTACTTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGNACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCNCTCGTTGGAATGAATACACAGTGCAGTGTTTA
+
EF)-@//=2).1B',B/,7FH#F=57$+-.G!)2H8)1G$GF(66A/E2-G!H;13:.1.@!*(".*4',H#9.9B?'B%9=H2FE-8=.E$<:>>G:);G04&@F>0G";%24;926(9/80)6.'$=EEC3)@0D29C.,4A.5,&#8.90-4@'4<D+%*C-C)H:H@+#'2@"*E*$=;E!2&8%/!--#1?;,?B-.+(=-;:2";'A31<;/9.7A4>,GG
@r5895
GATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGANCAAACTT
+
4G*8G!9$%))(,;B$*!3G64"&120,1*+%;*(&?7!)B-E!1!G
@r5896
ATTNTGNCNANNTNTCAACTGCACCTGATANTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAANTAACGTTCTGCGGTTAGTTAG
+
*!""&*%"%'#!#)+'"$*#'$&('$%%#&!&*)+('(&%"'!%%"!))"**(!)*+(*&*((*&+%"%)!%#*(!(*)#'%&(!)'"%&)&)$)#$"++###'#&&+"(#%"%'&"((
@r5897
CTCCGAAAAGTCANGACGCTGTGGCATTGCAGCAGATTAAGGAGNGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGNCAATCGACCGTTGCAGCAATATCTGGG
+
F/?')C1<DC)#5%,>EC%4?=-5%*@+2:C$5((0+@">7)+4;8!/'%$<%7#9'8>?=<>7$#?1*8/*==,21&0E4?7,9(#-E)*&H(!!F<(,)#%)*'1!19!."9
@r5898
AGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGC
+
:!#)C"3'DD7A!B0572.(E@>@84E*)"G>=?HF5D(=85?;?;HH*?E*C4+G7=E==8!EB/ED:"489&-B02(*")-0,:8=H5-!0D+6-;8.
@r5899
CAAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGANACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAANGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAA
+
BC@/@91A"+9>#ADD/3DH95(-=9$%-B/2-52".9A/9,.!1&>257/0@*AG,:5B$2961>">,+#0G7;+.:3A;"$=,9(E",B.*!;!&<>-/H:("D?'/G)D'$>@5?=H.!&0-"32@:=B:%<7%;=%6"'36F36E/!C?(=*2-8;$>8/@+!,8'@/5.F$@:+/$/9:32)8B6F%?A/"<.#=D89$'<1>#AHD:'96,D8G?4,)2/&1G+AF("G&/$-*,!0(!%96>
@r5900
TGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAANTCAGCTCACCGTCGAACACTTTCCCGCAGAAACAGGCNCTGCGGGCCCGGNGTCCTCTGTCTGNTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAG
+
,8&0H>9$?/G!%=4E#/$B&G8>H("0&#E$@%0H==1*,F%/58@$91**)8BEC/6E)3",7;&6'=$6CF('7B$?;1>7.8<8)E:(+*1#(#0=/+0?-;5+E+%+'%3=##5-//*;/'5?9$2%E89&.=4(2'4&CAD<%,AGH%C$"8%$,=2:=G77*0+<+8:.#
@r5901
AAAACCCNNTGATGNCACGCTCACCATGAAGNGTTTCCCTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACA
+
'$#$)!$!)%)*)!+%+'+$''&$%"(*$('(#%*$'""(+#"$'#'($")!"'(((*&'&*(()!"*"()'$%$%&))&!%%$)$#%+!#+'"!#&'!*$(((!!!''%+&%%#'%*%'&*#*(&$('&%'!(%'&%%!(+&%#*%++(&$(
@r5902
TCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTTCTGCGCAGAACTGATGAGCGANCCGAATAGCTCGATG
+
%>/#@?*3:1$6/>$&+=8%H(&!35=#+/%6>FGAE.3>E4,%@GF$18A;2"*1$--,;7",1:!A)(,+7'.=(&9+-)#?H:"%6%@/!@161>BB:!C09EE'222G7@%/.&>-G1#?;1-?%>&#AC5/,()3D/H+D.4'*56-+-55,+@7,E@D(*,0@4CB.4@GB!HA*D5C2B2+;)7-&53"2
@r5903
TGCTTTTTTATGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAA
+
0,E**"!360",3&H<1&$780E/6E:D'#3,$-;@52$1@1G2"578!.-91!.6-'960,@3!'9682<A3!78*%82:B8&(5*<'!@!H8F$
@r5904
TATTTGAAAAGTTTTCATCACTATTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTNTCTACTCTCATACAACCNATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAG
+
1=('#4-*/'C9"GFH29&-D&<&=0-B"B&;$@G7F/)%,)D,1%H!F+822).:$4>($,E#$"0<(1B77,<E+/A0B'=2*@)41;A/:57";778-'$6"?9$$9.&59F8H?%,!889@$7<3D0,('7+<,3%'8#85#C3.EB<4%7B8<:G'$<?$(F
@r5905
GTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCT
+
F'3.:+'>F0=D5=C106%4!4+!/%+?FG&+6*ED5(8"/D(/5)'%0
@r5906
GGGAAAGGGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACNAGCNAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTGCTATGAGCAACGTGTTAGCAGAG
+
(#%%?8>H,"*5:7@.0A6A8D(?A.9-<4(@DC@=25F8-;,G$.G4(C,G08$>4EH+&'@!,,2B9:'C%F&0><)%43""(>=A!8+;3%=.-H*3=>$GA0,0B,6;(85%9,@'/F725(;)7D0:2D7#H3(D3H.;4473A1><#.<9"'-%+1$E@A+621=2,90.E=;8"6$5?6:B<3?,;DH7303
@r5907
TAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTNTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGAT
+
&82483490@&E.97AB=15D48D4HE!=CA7:0B'8+<,+@*>:@/@&C>F*%+308=%D&>D78AA7B449365*5'3"4,)*>C)C"BH$21;G&=#&;#?F'/(<E9D#34054$E:#A=:E@&$.BC:4E<0C2&56?+"-6,=
@r5908
ACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCA
+
&****#+'&"*#!'$'&+)+$+%$)$%&%&"$%"!"$+"++("+%%&+!#!%#'"&!#)++'%%##++'"$)'+$%')'("!#%#!*()#$+*+!'((+'%$*'&"#%%$)$$&%%#))(*)
@r5909
GCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCNACCGGCATGACCGTGACGCCTGCCAGCACCTCG
+
$G@/'&?"*)6A<0';H5308*G1$D$D0E01=6.?%#HB2B*&55?(<CEC9?).5@4$H84?,?/BF
@r5910
ACCCGCGACATAATGTTTGCCGTCTTTGGTCGGCTCAATT
+
0E.6*>/G6E8(G$4D5F6*=@;:%**&)H""5"$$:#('
@r5911
CAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTNCTGTTNAAATATCTCCGGCCTCATCTTTTGCCCGC
+
2(F.6#;@,<1"F$B751!;%,E#8.7C.=>?A;-3(,7'7.6'8.H."H+=/!C$;86$=&?/9)&,D*,=9H;?"1@8:*2"6933$+#9(7-D5AC-#3FF
@r5912
AGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATNCAATTATGGTTTCTCCGCCAAGACTCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTNACGCCTGNTTTGCTTTGCTCGACATAAAGATATCCATCTACGATATCNGACCACTTCAT
+
#33,:$BF798BG#90'6H/(@HE-9$'"$-;)BF:?A!?;.3)=4$>#,71%73E8"#CD-*1D1HG=53%#D5@+950"17+H'D8%-C<20*;3=$="24C2?2=6F14==78!GHD@F%-HH82,15E4"!!E60!C6CA1.(%;*.&,;3#@31D/F#E+7GF#1EF!/%#6-4"F(<D+4&E6C,F*A(6(D7;4E+1#=G2*$9-"2*F.B-@4(<,<=5@1,C
@r5913
AAACAGGCTGAGCACGGTGTACGTCAGCCNGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAA
+
-?2,&;>.2-+7=370CE*D>:083$>5;39H4*E+!==?&75%=/.1;5,7@%C/=G@>?&3H(!4
@r5914
GTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGT
+
!8#+@&7G=$<$;>#>52505&;@%46C<--1B6@46E&5$%6H7108/3/9*)4*)1A,&E5*H5&7<)?%/1B99BF32C'+().;?$G*HA8:>.>
@r5915
NCNCGCNNACATANTCCNCGACGCTTTTTGCTCAAGAGCGATGTTAATNTNTTCNATCATTTGGTTAGGACAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGNCATGAGGTTGCCCCGTCTTCAGTGTCGCTGATTNGTATTGTCTGAAGTTGTTTTTACGTT
+
!#""*$#%$#!&*!&()!"&!)%++&**''"+$#!+*$('$&$+(#*%%$!'"!#!&'$)"$%&)(%'#)&*&!&"#))$))#"&+##+)$)%"!#%$*+(*')"#$))%')++*(!**%"&"""'!&)**+$##))$"$+*#+&"))(*)$)*#)&)"&%+#$*&$$%)()%&$(%
@r5916
AGTGGCGGCAGATAAAGGTGACCTGCGCAAAACGGTCGTC
+
=2<:&H!2+CF(HFB)>6E)F#1%)CBD=<%!C<4%@9DF
@r5917
GATCGTTCAGGCCACCTGGGANACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTG
+
$!+(*)"%()(**+!(!$*!("&!"!$#!##!!(+&)!*++#%"&%**+&$&#(&(%!#+&$)$'*!&$%''!&!(&'#))&*(*&*%&'&$(+!)"*(*"##'"(*"'"'&&#"%%&&&%+%!+
@r5918
CGNGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTNTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCNGAGGTATAAAANGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGA
+
D+$'!?"3(-ABAH24"/A;"='(?),1:(0!@!,C<"FE(:+(G5'E/%2=!!&&?F&FH@816DF6%9:$,>/'-+0@?6B*8)*2423'%;&CC+.B'6"('.&"#09E*G-6(!,G;5<7D<<@416=:.1!;5HCD&D;/(3@9"&%&8H"-#(C/%99#,8#GAEAF*-@#H0@)&>*D*&=%8'F81D7%F??))-GD(:'.4?8
@r5919
TGTTGATTGTCGCNGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCANTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCC
+
3:=A82@,6FC<9)&?6%H02'8H;/D"9*>9G&0D/DC-!-@:;!DB%5=(#$-/H;;%>.GD.-8H;E#?E%$1779-%<&1''()/C$:DHC.%+2@A8&H&6#6A#80:3HCD1#C6E7/F671!C-*AA)!9D:,2*02@1@&+>@?1,0E(-F6"/*2G(&H21E+>:%'?74+/C%!C&</B+C2.(2.DG>A%F()1B(&>D*4&-C-$B+#4$&%;8*6*+,=:&-H91(3D>)4%
@r5920
CTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGG
+
2.B3H.&'FC%-83&8+/)<4@F<0=6'69&4;G?>*F$-5:BC-67A;1:G
@r5921
AGTCATATGGACAAGCTCATCAGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATANAGGTNGGTAACCAGCCAGTNGTGCGCGTTTGATTTCC
+
&-@H2?@E6=G?9A9.3"&5FE#7D7B)?1=58>)>7-!8A#<22E0GB;?H@9)<>24%E'4C@<F&FH/4D0?D#1EE)$1<C&.4),1:B06';1F9:F0;;H)H80'A
@r5922
ACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATT
+
G;A+8E4&1-.;H1+5(&/>A?6,6"4<+C&%1-,-%@,?4@-:7DH!1-A;A(E8#B)G.0H
@r5923
GCTNNGAATANGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTNTACAANACCGATCTCACTCTCCTTTGATGCGAATNCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTGACTGCCGCA
+
$&(#")"&#&$+$&*#+'#"'*(!"(*%!%)))$"!#(($'+*#***#*+#+(#!#+)"%#+(*&%!&%$"$$)"(*!*'%!(")+%&'#!#')#!+*)%*$%&$)+""%%*"'"+$!+)"($))*!'%''('#%++++'+$"*#"((!"%('$&%$&*#**!+'&&#)+&#("&&%)&$%'#**#*(%'+&)(%+#((!'$*&&$
@r5924
CTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGC
+
1C=>?,&(*/:-?55@@'>)73+#*?,;>!-1*F6CE6+@210E2%H3=-,*?13+,=#40/
@r5925
TAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGTAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCNCCAGCAGCNACGGANTATCACGGATAGTCGGCTNAACGTGGGTTTTCATAAAGTTCTCGGC
+
5/?&%/<*C006=CG*7&B#E/<0C4C3>2BBDC@0B4H;165696##D-CH2!C@;99="G#*3'A2*&?B>C83.F8:).5/*++-$2'$=/10DG:(F!;D";A.C#=GB3)"!"+;)*892E:D0"!(1@*G%C1*%=2,8>%(E1:'7:.1/&?20?*3-DD)5>
@r5926
CCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGNCGCAACATGCTCTGCTNATAGCAATTTCA
+
5B,?A9)B4%F0D0G&(EB16-((2%:==44H8E:99;;CG%)*$5A)4%D;-5+(78):75)D;!$6$2=C8C?$GG3
@r5927
CATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTG
+
9F-=@0C+2D"4AH$*+$*H5D9*,.3)H9B0?:8#C(?&)6D.2517
@r5928
CGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTA
+
%'/"F<!#$<>H.B4.%=3>;C69<AFB7<H0"(&+&#""G"10.%1CD4DGG0C'0<&'837>"C9*,7G<:E>#$&@>A4F'#660=7$':FE)GD*B($7(%.!%67/3"0"F'F0
@r5929
ATTACGCCGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTNAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATC
+
(+')*)'"!((*%("*!+)(#+#$)*)#+#(#*!())"")*'*"&+%)!!")!($'()'(!'"*!)!$$&#!+!'(!*$*"($)#"'+#(*$+'#"&!$&&'!%'(*&%$##$&'"%(%+&&!#"&")'(%&&**"&)+*+$$)
@r5930
ANATNTNGGNTTNTNATTTGAATCAATTCCAATTACCTGAAGTCTTNCATCTATAATTGGCATTGTATGTNTTGGTTTATTGGAGTA
+
#!&)$*&#&$)&"$$%('*""+&*((+$!&#*$+('!)+&*%!)&&$*#"!(#*+&%)+!%)$("%+'#+"('%$!&(*"!*)!+"$
@r5931
GCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATCGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCC
+
B1@!@:'=!C0%!&@?<22#+!*6#3?%3+H%&&,E#GDF)$2*0!"35*=--8D&.G:F@C!.0%<0C1!:?!0$F?E?!.C74'/2.3#;$>G/A0>E:3),C015<'@0B5:CF.'*$>4#'%/7A7/:/C8@)#95>E934E($G
@r5932
CACTTCCNTGACAAACCGATATGTCNTTGGATGATCACAACCTGTATCCATGAAAACGTATGCACGTCTTTACCTGCCCGTCGCTTTTGNTCCTTTAGCCAGAGCAAATATGCTGCCGTCCTGCCACCGGAGAAACTCACGACATTTATCATGCAGCCC
+
%*?+*94EB"&9%H+H=055H@1&)9&C(6281%8/<#H932B*$<?,C.H5=0%2863<4%/"%=15)8+*.)-.;G:5DA-*6<;9,4-8;3F!90!<48-/!7>@+B1)(0=G7,AH9;(:*';#:+.?)B62>/<53";1'.%5%8%4D1&'@$6
@r5933
TACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCA
+
7F0#93FG:"&!,,:-*,!+#*'<C1@.(B166%=6!?!-3(6/?*<73>%?=E44#(+),03%*'H1:FE/,DB-(!4G1HE:.5B5*+?-=F.>C6B;+,/7E';.%
@r5934
CAACCCTNGTAAACACCACGCTCGGTGAGACGTCGGAGGCGANAATTGGCGAACGTCCGGATGCTGA
+
"&((*#)%$+$*($(&'!%!+*!&(*!($'++($+))"*$$#(#(*"&+$'&*%&%#*&%#&&+&*%
@r5935
TTTTGCTGGGTCAGGTTGTTCTTNAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGGTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATNAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTG
+
,-/+@?&7F"0F5B3<9/(G(2')8-G=&F"2;B=E.-+@4-??"E@GH=E)$E-,1-*?-$G7:&?E25;;<%0*".>&#)B98=-8+H948GH?+1%+"<7=G=6,!71F&2=*.:$@#F%@08*%;?:/$,HFD.F1'A3><F4D996E7<&A;6#='0=-/-@C-5(D&<B2=9.2D/%2+AG@)E;3E<39HD+#%*0"?*39F6333-;-0GA1$&F)F0AA0(#-34?)-")3?:46C,5191FF6*?.B6<;F+=)"7.=6(D2HB0BF*:)<=&<6@5?D,@#$96-5<73,)+2&'4(EH-DED9-46(,8G9<'7%?E-'6H6):@)6?.H:/;:G196
@r5936
NTGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGAC
+
-(<C+=<"!@-D!&8:9HA<-;.59#;5E8#D:-;>/?A(9?58>"9)*E=%!-E8HA2(,D@D3#C-F43=,4C)A;-/@H4G,=8F6*A5%)!?$'G62@C2@:#1<-320A8*%(<+>GG:6<!<&.5&DA?*(+%9111&1-5-E'EA,?<,25<A%>!
@r5937
CAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCA
+
(8+H+<$>A9;/B?G#%GA49.C1<8&2;'A#08"8H:5!
@r5938
GANATCTGCGGTATCGCCGNTCGGGTCATGCGTGGACTTGTCACGCTTGCTCCACTCAGTGCCGCCGGACTGCGTGATGTTATTCTCCTCANTGCGGCCCATATCCA
+
(#%!#%"!('*(("#$)**#+!#!'+%*$$'&)#%&$)$+"&)%)+))$%(''&&+'"*)"!)*$(%!($"##)!')#)+"(""+$+'%)#'$*()$*$!$&'!)*(
@r5939
GCTGTTTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTG
+
">H62'%6:>,.H1-)422%98&/2*;2E!HB6:/+.1>;="A(2>7E?)%5((EG?23A+
@r5940
ACNAAGCGGACACCTCCGCCAAGCCCTGCCGCTNTCTGCATCAGCACATCA
+
##&(++"#+%!"*+)#(%%!%!*$'$(%!!+"!(%#$%*&*$+#)+'%&##
@r5941
GGANNACNGTNATGCGTGAAGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTGGCAGGCTGACGTTACTGACGTGGTGACAGCGACGGAGGGCGAGAACGCCAGCCCGGCGCAGCCGNACGTGAACGCGNAGATCACCGCAGCGGTTGCAGCAGAAAACAGCC
+
%*)#!)*(&&!)+++&$)$)&)#+'$'#''&%*!#)(%'$*%%&!&'"*$&)$&+%!''&+*)''"%!")"!!&))#(%&$'!!&%%(+!#(!*"%&$'()"!%)!(#$$"**+!*)&"#""$*!(("#+))*))(!""$$*"(%)%+*#%+'*+&#)&%+&&%%(**('*)#!!(&+#&%$')!"#+%!(($'%#&%'#(+#%#$!)*)%%"
@r5942
TTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCA
+
.09++C:'H1,D1(EF!F%D4-8)?1&17831$*B3+"<!?';:E;=E6/#F#4"<127H@4,
@r5943
GGCCTGNNNCCATTGCNGGATCATTCTTTACCGCCGGAGCCACC
+
#")&*"%#'##"%'#%"+(('*&*$"%+$$*&+#!+!'*$"($+
@r5944
TGACCTGATGNCAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGC
+
1,H#61B6'+6)@C'3FC=&>718:=04E8"CE$,5E#:BF5</?D+7$<?3.=667(EF06<5;:@?8>$')'9$(!95CBF9"D5D0(95733D$CA@47.==9AC('G#$4>;)+@E5:0EC'9E&.5
@r5945
GGCGGTTTTTTCTTGCGTGTAATGGCGGAGACTTTGCGATGTACTTGACACTNCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCCTCGATGGGTTCGGGAATGCAGGATATTCCCATCTCCGGTTAAGGATGGAAGAGAGTATCTGNTGCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTA
+
0!GA2+$1&3#5!0:)(+3%<1:?$-7AB2;F29D7F>6DD:30<0#9-#;,?@>1=,&!>&C(G"0.@,$'+*<>%#HG.5F5DD77:+*B/'$:*?;.F2'7?4D97)"/,:(A*//?*'&(,@47(2@6>9$3B.27?C24//F"DBA4G-39.;>$.=#8A3.*@%*=D,C7(B3#',&*'*HG/63'98@*?>3.%;=B66
@r5946
NTTTNGTCCNNTAGGANTCAAAGGTCNAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGNAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATNCTTAATAAATGCTCGGAAGGTNTGATGCAGATAAATGTTAGAAANAATTTCATTACTCACTTC
+
""#%$#**&!&'("'&)'"!($)(&(!+('#&#"$"$&$()**+%$)"+#"%(&*$!+#+!#%!#"!%('!+#!"(&)"#!+*""&#*+%(*'%)""&%$"%&$*%")#%%%'")&$$++)*$'#+")&!'!$%$*(*'#+%**&$"#*''$%("'&#(&&!"*$+(%")"*%!$+$)*%
@r5947
TGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGNCTTCTCAGTTCCAAGCACTGCGATTTTGTTAAGCAACGCACTCTCGATCCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCC
+
&7G%:61*3=-A@CE(./C%7H?),.4*;%;)<8<"DH9=:0)<.43E+!=?%%/5.??DE%/<A:1=!?A.':(,:<8?4B/40?/H/=;2,3C;HH#A<7;%G9E*G*02:E$+4E2@./0+.@9+G&2%://
@r5948
GATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTC
+
<:H-7AE<CG(<73$CF1#HB63++#.>!2A7)G/?"!-#<7:-9<<=>?>G9-%2).+;:HA6#?*<:AB<%#&;14@2H7%$/F04),=A5@%8@E1#(2?7>B<9@2>H#)10<>!>1:>?64')CH3.',42*F(;5$D9+@0B2?F46=6)>5=+'@(GC>>!#(-),:2(;"?:+
@r5949
CNTCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGNGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGNACCGCGAGTCTGCCCGTCCTCCANGGGTTNAAAAANGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTC
+
'!2C72'>G%#66"2)99FC:-C@@H9%):6C+'//=*1-/85,*->.#&H@?8F)?-$2H6'0F<:,5H23.2C1<A14B'8G0)*28:07GF/E!(3/,D2-,#/$&+F:7(1GF8"/*BE<;?(?A1GADA?81,1CD*&E#GG!DHD,.,AB?+8B0#(C$2,(4114!:1;&#0+DA75%'<B-(*A:4.*$=)%C$7$1;>A:%;3&+!!H0D2
@r5950
CGACGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCG
+
)8:<?/%4&4;%!80$8/*<G75;%3(C-+:5*-2'9+#,AE"@%!!4E49@72?%*&"E78."G-&@B##:*?=.E'<=3H3;E:2
@r5951
GCATCGCTGTGAAGACGACGCGANATTCAGCATTTTCACANGCGTTATCTTTTACNAAACCGATCTCACTCNCCTTTGATGCGAATGCCAGCGTCAGAC
+
6B@0=A*&!5,,4'54*A5(*>?&A;-0"?2)6.6/50#,(:B8B+>,6680%&D%3((@761E+&%4:4!/BH*91/@4404#<*G;2G5BFH99-,A
@r5952
ANCGTAATGTGGCAGATCTCGATGNTGGTTACCCCAGACTATCAAATANGCTGCTTGAGGCTTATTCGGGCGCAGATCTGA
+
("<"D:EB!H(>#=G5%1+>A@/7C$)/4C>6BC,DB6@#)B%8:)"!?BE?."G3@E3#19G)-<.@8&0?$>,3C!A>D
@r5953
CACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGNTTCCCTANTGTTAGCGCAATATCCTCGTTCTCCTGNTCGCGGCNTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCNTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTTATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACA
+
&D0.G,#568-.#BH<,66;C09!>A*73?14!+:BCB?F5(:+6)50A2BG>DE;$H.E9@8-$*.10,-8,,(H.84.('%,36<,'/":<<"#=3&D,8F,39HF0&H8"4@")-'77?$7/@D&H4/109)@8:4+@71=$F=EA+*,56@!'*4404&7H/C(,'5";)#C*@1#77CG,2!H'%>2=@8*6+(8,H'F$<8);;33/"4H=A2GG=5=.,8CH82,3/7>%6/"-.98H<;6&<>C#?:E!656*ED(D2?29.G,'=+4.%>%74,@/54"A@5/6C$@G5)+7A5;G:A(.?6=G0:F+!54>8H?;?21,62$&7#)AD&04",6C03*?'2%05*G)3*F"".
@r5954
ATGCNACGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGC
+
##)(#+&(%%"$*$!+!'"%(%*"$$#+%($+)#+#('+!*"$**)$$+!"&#$"**&&)%#!+&(#%(++"''*&'(%#+#)%*)%(("#*#%$$!"*#*
@r5955
GGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGNGCANATGAGAAA
+
'./++#AE(.14;&42*!&C";@5@30!(@/)6=09=-0H#=+'$'5#A1:BG')=.7#"-DB,4,354105#)>@,<72C4$B&3,+#6%@C
@r5956
TCCNNCGGTNTNTNNNNCGNCCCTTCGCTGATGGCATCGATCAC
+
'$$*&"('&%&$&!!"!*$'%+%")**#&))!)%+*(#('+(!+
@r5957
GAGACGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGT
+
)&)%*)$('(#&++#!!%&%%!'*&#($(*%")))#+&$$&'!$*'%%($("*#!###'"%%&&(&
@r5958
TGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTA
+
88A&/.263>.60@)B?*,A6A?64B?;>:F:G7?GD6.%<0<A)F.8E(E&-D$7"B1AB)H
@r5959
AGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAAC
+
8G9E$@$&AH0A:.AG*;&4)$0@;6'<<"((-E9$B3F5
@r5960
CGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGNCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCA
+
C9?B!"!3<>#HH4'9?6="HF!4C!A-(E0"3/#!F7)%>)BA'@;#=G$=G69<'.H3-;:+2:"-7?1%FBF>9@(A(/'3(6!>-,A<F8-)!=-CB2!<(&B5&@.&)15E.HA5D@FC@/C4;;$<&A#
@r5961
TGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTA
+
G#(1<!.-H-AABA$+G'==2?%-")-H-4%@,'/62/+&//&'EG$>D0/;,03G4,003
@r5962
ACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAG
+
-B>./'5FF?F<%D1"+#*!13!%"!9*+F48G=66F2)C5:=7*FE&2$'"!=EA$%-F@=!0:/4/#51$*8F89E
@r5963
GNGNNNANANNTGANCCTNGTCATACCACCGGCCCCAATGGCTGCCCCCCANNCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAAT
+
*#%!##&(**!!&*"&#!+#+'&&#%"#$#*$("*')('&&##*!'"+'$%%!!$&)#**&(!")*)&(*!#%#'%!%*"'%#+("+"'!'')
@r5964
ACAGCACGACGGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCANGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGC
+
H)7-G@D1=E(D!@,2&C55#+;B'*9G+,C7EH!HA6><+,4;,*>%8F$)"7#/2C+AH@6H:$7H*:A/%.1,H,:(16$*84D5,94?:AA#:A15/H7&-:G(A5F,FD"4?@(",93'!BC8D1>4>*$3,!)/%8;&,D$=<:)!;'3!"(B3-,:3:;B0D,#="%G%
@r5965
CGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAA
+
#B9#"=3=H+12;8HEDB/?9"A9./%/1>?H9'8'957-";&C'>1?AG>7D1D4-8@A:@9?*)/$.7H/H2'08DEB<&>;A*HH%9
@r5966
ACAGGGGACGCGGGCGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGG
+
3#6%.5>G)77934H$?AD,1F/34!.$-::/E'69&&%1<2'F!*E./;D'=<$!
@r5967
GGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATA
+
3?H@A/.&C7C3:>C=F8#%$"!,!G,B<9#*,E(8E%(!&'2D9>'5F>,,5=C(>*-A;F
@r5968
TGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGA
+
G)19$F4/(.6-%CC$-!==)&)H"8F%670G>>1DH1'5B/!&A23C&B/
@r5969
CANNNCNTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGGCGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGG
+
'#%&!*$+*)')'#$($('%#'$+%"%#%$(("+*))("($$+&++!*!))$'''++&)((!''!(#((!!'&!$)%#%"+*'$%'"%(&"+(+!!"'+#!'%)'(*+(+%$(
@r5970
ACACCATCGATTGTGCTGGGACTGCTGGATGAACGGGAANGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATAATGCGCTA
+
5%'8+4#>,#B4#HC%=8C7E'?>-&8+6-07D6)2'51;*?CE/C.8H91C$E0")5)CH5"/F:>H736(+/E!%C;/$&13))<"E@.8B
@r5971
TGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTNTCAGGA
+
D(''E'=$6;,85/3EA;1D#3+0B;,!$0>'C/3'/B(=4?C!3?.&!FD3-?-+'"BB@0=.09E2*5E;;D09%84
@r5972
TATTGCGTTCATNAAATCGGAGTTAAGGTGCCGCAGCAGTTGTCCGGTAATGNCCGGCATCCCACTGAGCAGACGTGAGCGTTCC
+
<H>C=<4E#:50?>=B&%7"5+##=1<FH+D>C>-<9$C37D*!E?=D/HH39EG&,G"(7HC+21$&240-;."*6'=%7*DF!
@r5973
TTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAAT
+
9D>A#!=!?#89!'H:)?/C74H67+@$FD#&)2A;?*;'1!7@$7!5@026;=5?$=)/;H-:A>!@#8$
@r5974
TCGCTNAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATNCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCT
+
F8*!#99/4D*<6'B=HD9D292A!2&=0"3!B=$65-3*GA)H9'A"BEAD=<6=1.9>,0#E<<;57HGDC4F7C(!'@02B$AAE@B//G6<G@&#H25H$10F/#>+#"(51B6&+$5
@r5975
AGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCANTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGNCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCNCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGC
+
.3:3)4E;/4+&#D@#,;3>7A0A6'2'1>'2)30?4C#/F</C+=#03G577C)6;2,$4DCD,7C5/!,B5"$58,;3B'#,5<5G'6CE.ED&HF!C$$8BA>&G!:45F+32*3*B<9#!!5+@D1-#7?(>1'>3%F.?C<<!&?4>'H$&/)A9B89)#<C?CFD;B9!D;C<)<#(B!%8+0>%/(@??,%#+*+,$'<?<FE"?62/EC/A%>3'1*C@"'$0;FF(%!D=1'33:>:6'G3&0!3(H'D-&%"G++<+-5)D+,;637#75.B88(33'G?0H"A'!A+2%/'(A&)+*0*G428:5@>"9D>,H:(*!D>1%+/?3&:GG&*.D8*+6-35!H;&
@r5976
TTCNGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCNGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAA
+
$&*"+#'!&"%&(%#"!)")'%')+'&*%%#"'('$)""'**!')#'*"%"*%#&#!+&$)'*%)$(#%#$"'$)*)$$%%&(!%
@r5977
ATATNATCCGNNNNTGGANCGTATATCTNATGTGAGACGTTGTGACGTTTTAGTTC
+
(%*%##)*$)#!##*!'%$$('($'%!$&+$($*+'"+"$")&+'+'"""&%+"'+
@r5978
GACATTTGGTATAACAATAATGTTANTGAAAANTGGAAAANTGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAA
+
;?+$H;#D!7$:D?.?58G=7!;-9&BC(#*3)E:@5:=HGBE;3D&8@:$>GC2(#(62"C<#+,(%2#1E7,;1F*=:772=B9B3:;30?
@r5979
NCCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTAT
+
%0!"*$8%..=3<EF&#,B(0<,"(D0)*!3;&.5A+"'7.7:29$&5./9"/D)9G83$(@E7=
@r5980
TTACTGTGCGAATTTATCCGCCTGCTGCGCCANCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCTAGCTGGCG
+
!*%++%*')(*#()$&#*$&#%'!#$"$%&''((&&+()*+&+!('')+(#"++#$'%+&)'#+!+%)$&"%)*$(('*'%%!%("(
@r5981
TCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATNACCTGCTGANGATCAACTGGCTTTCCANACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCA
+
11/H>F/")<0%%+?7&$"@=(G->668F/!D4<5>-5=D3)=*$>7D+"3G&C-!:(F:3%65**:3@4)#<6..A>#@$9'"9$!<2.H)74-C)%=+7)3C?:3'=14!-A&"0;:E(G*?5F8;#.*3'$+>6,C8(6/,6'(&65A*B?:=036(GA*HH@@&05@7:;?"
@r5982
NGCAGTATCTTAANTNTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTG
+
!1!!&>:*2%</-1)!$4G8-EH:@8+8*D.492G+;%>DB'041?#7G<;&1;@.'AA<CDH,G@9.04):)!9=6!%0:GDH1
@r5983
GCCGTCGAGGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTNTTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTT
+
H*E$HCE1##@.0!#B,,<;,17$(H$0@F+#B=03;C8H.HAF)?'"58EC6A9/72=ED0%'F3EC=:#3;+*A2-B;A@;<<&31"-3B)8)%3G95HB19>"81%1A'<0,,59"G>E'D&.'*.D01(@-,/"%2",+.68/7'$<G*)5,9"55B?>C>=6."G
@r5984
GCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACNCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATNGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTNCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGC
+
@9B&'=:A.?=0:7<";D;4G:F,$%G,#,F5&,7+C(+51#;!1G-GCH@&!/"7?+/*:69-$93782;'B6!4@;<3G(//?.);%#*=>2+"C:(A$;+657?<F!AEE*-"-C/<!/:-6&=*"-7C3#(3C/8H?4)B=.#3D/7GD*E:0CA@28;5'3%0=>-G/@FA?:>=2*C.#3C1%C4>,":9;0'F89%.)5%'@$79,/!!6F9:3H5(;0<!B'2B82E#'F21*?1D3B"?85*92?5)495F!6$;7+>@$7674A5?0:A5!/(DD3DF4@F$5.)*CHG,69H(//$@A26-/F-4>)G1F2/(#8.;4A:3E)&*550++"(C,7C9>3D?.G>1875GA*@&5BE9%)39D->*-4FB:-!);."HF7-63+97/%
@r5985
NNCANNNCNTNNNCCNGGNNNNCTNNNCCCTNNNNCCCANNNNNNTNNTATGNGNANGNNNNNAATATTGTN
+
#!$"!!""!$"!#$!"$!$$#!!#!!"""#$!"""!!"$"""$#!$#"#$##!!!"""!!!##"!##"#"$#
@r5986
CTCTGCGCATCAGTATTTCCAGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTG
+
)!)%(&+$(%!++$+'#*)"")&%!+&%"*++')!#&#)+&!"'%(&!*$)%*'&'#)#*$&!$+&+*&&"")&+#'+$"%'&!+()''!'#())"))
@r5987
CTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAANGCATATGCATAACATCGTCTTTGGTGGTTCCCC
+
5:,03D@=H9+>A>.#8=2+E("C-.B35H#D/#C;;@$"%'4G-ED80BH2C5;+A=42?+FFC'0H+0&
@r5988
GGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGTCAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCG
+
3$.DA+!8*'G;@)*C('A/:7D44#?@@?F$/E,3%6:6-0/HA'-=0A@)G("*E#;;!H-4%9(B?1.=':!'&@G7FE9>/"3)4E:A%+$3#3"F?2(3B9,,79-:-2B2"C%E):F(#27
@r5989
GAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTG
+
G"-A-D#2AC7=HAC<909A$+*D1G1+.8*F!G5*"3!')@
@r5990
NAGGCACAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGANGTAGCACGCAGA
+
##$)$$!)+'%(+'+('$"%#($&&("#$&#'#$*+!%*#'$$#$))(')(*"))%#))"#!#++(&*!)"()$)('&!"%#$%!#!(&!'&&*!!&)!*('!'%'''$%"'#%(!'#$&%%&!&+&%)($
@r5991
GCATCAACTGAGGATGNTAATAAAGCGATGAAACATACTGAACTCCGTCCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGANGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCCATACCTGGCAGGCGGAG
+
G>?@1<G3906?$9(B?3(*1D4$))D".G,;#'&2F2=,%F!(.2(,%@%'3H<EC"=++BGE?&0HD<AB7FFD-E<-3)H-;@&(EH%C7!?547.G5D9A!#&B,;C%HA(B:!H*0'#2BB=&<:4.0B+#A<?!&>=!?C"*,2-/8)G8G9CF)E&;1>4B:%@8H5+!+-CA*-==?A9D>)B3&F"!,)14)24@-E*+3@
@r5992
ATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTT
+
:D<%9)FC$.#8.7F))"37HCH.9&458'B0#3(G."#+.)4+$F&D8:
@r5993
TGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGT
+
B3@&6*@*(F#;&2%6")F*4E6'3>),+9F#BAA)*B*"GD92&*"F6*0;.&;E4%;"B7&1,?6
@r5994
NGCCNGAGCAAATATGCTGACGTNCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTNGCTTCGTCTGACAACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCNTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAG
+
')%*$%&(+%&*'&+(&!*%$+(+#&!'#%#+!#'&(+&!"(#"'&(%(++&"$%'#"'*"'!&%'%%""$&%'%*%%'+!)*###&&&%'$#!+)"&"'!+"&%)"'!!&"&)%+'"*)+&"'(+*&+&$%#(*&!+!)&'+&!#!#$$&+)(&($#!"")*%#&"++'"+%+$(&+!#++"+()+&'&#+"'("$%'+#*%'#*%))$%*)(*$#'#()%+'*%#('$&'%'
@r5995
TAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAA
+
>-+<1.*96;9>@6A*%;HC6$B:C8D7*E"A@:%6>/HEE719"/F>:&5.=E?54?A92*F@)2-5)4-81'@4?-BD&H
@r5996
GTTNNCAACGATNNNTAATGCGANGAACTGCGCATCGCTGGCATCACCTTNAAATGCCGTCTGGCGAAGAGTGGTGANCAGTTCCTGTGGGTCGACAGAATCCACGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTANCGGATGTGTTCTGCC
+
$)&$%$$#&*'("$#+!*)&+%(&$+&"*"#"(&%+)*!))'%(+*"$"!#!('"&)')!""!+)%!'(")!*#((#*#*#"%')*"**()!%*'++**&&((!(('$!'!%)%")$##)')&$*+#&!+)#"''#*$%(%)"!("'$!!'"%!+&!!'!()"$(+"&$)"*)"!#'$*''&"()")+*'&$*)!!$(('#'))(('%$()'*+'%!*%#()%+&"!+()(
@r5997
GTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGNGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTCAGTAAATATTAATGAATTATCAAAGGTANAGTAATATCTTTTATGTTCATGGATATTTNTAACCCATCGGAAAACTACTGCTTTAGCAAGATTTACCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGTTTCTANAAGATGCGTGTTTCTTGAGAATTTAACATCTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTNATCGTTTTCTAACACGATGTGAATATTATCTGTGGNTAGATAGTAAANATAATGT
+
;'$).F0B9()2?<,)4C+;7&0!7>"!;1-,!8G=$)F7G7(D#DEE38$-#7E<,%*A0")>:)3#CCGF)&*@#$):((-=3E%('H#H+%9?ED621;.H+!??#>BF"+A+,)"!?<3%:%:7"&):/790G31:180):&ED,G%D?2#':F&@H+&D/G&'D2'!"(>#/"+-8C:C$D/"#%!:8;%3:.3!:#H@G#?&"84'077&:G7'(G3@'8>55H-G1%7E/$=9<#96=:-8B8556170&&"8"4?=#)'%88G4%!28A4H%2#5!D6+B.41(?&#.<$B;;;2(G49/<8.<;H)#B?71)-/(<"4:1@A(A.2$-<@?-4*,+E*:CG@A8C72&,!@C7B@-=H4B3(F=*#/H=%1D!65=C?G$?G?DG-A:%B/4E23E?/*&1=5(03)2H%1%H2H?9C$A&=7@DH%G,6'(H$-%'8CG6'(!7B<=GBFD@6A
@r5998
TTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGCCACCAATGCTGAGATAGCTGAAGAG
+
AC78'2,(.=*";%D3!4*$H*69*)&;;B<:?7E6B?<>>(%F>.>5#>$<@B>!'(A(;@6B87C4%/3D&-C4-4*G8G
@r5999
TCTCAGACTCACTTCTAAGTGACGGCTGCTTACTANCCGCNTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAA
+
!&$%&"+!%#+"+))%'"'#$)(&"$(!!)*(("%*#")")%!"(&#!%'%((%('!)()&!"*&'")!&'')&()"+!'&"((%+#)#'$$(*""(!'$$$)"!(+)'$!+(+%#$+&+'%&%!+'#%&*(+")+()%#)(*)%'"&++#$#(#*
@r6000
GGCGTTTTCCTGCTGAGGTGTCATTGAACAAGNCCCATGTCGGCAAGCATAAGCACACAGAATTTGAAGCCCGCTGCCAGAAAAATGCAT
+
'>4.77&D>%"'%,:96B.)*$,/B-64A47G913(?/?,;.05AG#-G*FF8"*-6F2271;=%GC&D$9HF<,24)940--63!!03&
@r6001
GATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCAT
+
FH+81765B>/=#<G:0805$'7C>F@0:1C,%1#6#9()H
@r6002
NATCCGGTTTCACCACAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGNCGAATAA
+
!&+($!+*""!#&&%''%!#%!$#($%+!+%&$%)*)+#)"'%&+%*!$$(*)+#)%($$&%+&+$#'&&)&(%
@r6003
GATCGGATGATTANGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCNTGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGC
+
B7HH<34BD)-..*A,%!B7>?:8(@7!B?2#)C9*D%%"-%H7783>*&E+*G'F@B2>E<=/4C9:..,<78A@D<3%:8GB>!1&);;8HFG+&.H2&(3;6,.?;7A+<;+??<3A&HDD1-.&3.#+&$2#;
@r6004
CGATAGCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACAGAACACCATATGCATTTAAGTCGCTTGAAATTG
+
8$$-<?7)/@/4;<E*:7/7+<0D+"B65*;'3ACH$/7(2A:=9?F<0'$,-7<FEG6#>D5B?)H'.%$5B!G0.;.3E,H5=:)GF0/"%D4/;98A1)%$2H?E<71).,&73!"*
@r6005
ATACGGNGAGCGGTATATCCCAGANCTTCACAACTTCCCTGAC
+
;;B%;FFC*A"3B)755839"*(B5')HC&'<F>8)E5DAF59
@r6006
ANGGNTNNNNCNNNNNNCTNGNANAAATANNGCGNNANNGGNNCTTTANCGNANAANTNNNANNCTGCNCANTTGGNNTGTACAGNNNGGNNG
+
$"$"!#"#!$#!#$!!#"$!##"$!!!###"!#$!!!"!$#!#$##"#"$$!$"#$#$"$$$!!$!!##$##!$$$!"#""#!#$#!$$"!"!
@r6007
CCACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACT
+
D=5@(F-":A&%0?/'D,,>>1H,A%!$)7,8-7'<;0EB"$*8;F147-64286-H#1,
@r6008
GGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGG
+
;0'E4)".**=<8?%+!)&EAG6G.B)B,.5+6,,$$;<BH>D!G4%%3>@1.!C@:D>211D:984';--)/,2!6D'EE9(9&?
@r6009
ACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAA
+
43&/$3,%08DB'BG@9A4C&3-=AH80AF'5D&&7G:*76/,)>"?"FG8GAD4DCHDG#+>A
@r6010
AAAGACANNNGTTNGTCGNGCNCGNCGNCNCCNGAGGGAGNGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATA
+
#(&(!)%"!!*(!!)$%#&%'!)($!*'#"((!$$$$$(*$#*+&+(')&("!&(%())&)**&"$*(%("+&'*#)&%$"'$+!#"()+%)**&'()$(
@r6011
GGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAA
+
2+.)B1&A0;<0H$(-=727@#*='#><.F$1/%=!#/&G44#!-+#&D#1/67BF+H<>E>=#
@r6012
GANTCANNTCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGNCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAANGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGANGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGCGCAACTCAT
+
(&('$(&*#$+&'#%#&*!""((%$%)&*!&"!$))$$"%!$$"%!+&%"'"$$*(""+%'"&+(++'"!&$')!#)")(")*)*$&#"+$!&+)($)+#*&*)!!&%##$%!(*!&%'#$!"##+)%%)*$""'#*%%&(#"('*&#"""+"((!"+!*&&!&*!%+!#"!!)#('*'%#%+!'+)()"#"%*$")'*$)')((*"#)$#!)+
@r6013
TTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTNCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGATGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAGCTCATTGTTTAGGGTTTGTTTAATTATCTACACATACGATTCTGCGNACTTCANAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTNGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAANCCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCA
+
;5D,%0#'#><B*;3"'-)7EA37=HC:9"+,@/C45*$?$F,(@<;A%46>13G)@B?97448.<.<D>;(F0'H/(%=G>H#69A,:=*4&>&./F">:*H,5#0@4-B%4F3A0.1!C$:"/G<1>.CF,+"D%<>AB>+E6B1>&<6.0/%+3D3#;D"90?%-BA@!%F6+$77/'%=.E-7D826*@.G/<?=F'>%H$&34D(8+&@A=2A$=;(5$3<32/0??2-D'H6C)C17=?#D?"?B>#5AF0?HF-*)@(A.;H/;1?%.54'!/;$4*33-10/B%;G(@25FB%F'B;#8F(?,1,H@33.F2@*70-3,8!1)-*8(.@9DE2>&.((%*3"DE<F367&3D57,/0@38H3..G*7#)7F5)$C3H.H9$>*6:9#/)!>4?35>=0<H:?)3=1;%.H7!7.1.F$/(E@*0B,6EE7,8;"?9=@&691",GFC/E84?G1@9+3?EG5;=:-;?8$&66=<$3"&??H6>;$
@r6014
CGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCNGCCCGTGCCATTTTAGNCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCNCGGCAACNTCCGGCGCACAGAAGCTATTATGCGTCCCNAG
+
:B=CHF2,/&DG3G$HG)!/=#C+257)@3F=:.4)2E++0$6,%DC%:*@3?*3E#$=0%E&==E#0$(1<FH3@C@"8/=1421E;#1).H8B$*+1E-$@@.8CC<H$2F?A*"-3)D7F>$*)@$%H<+D6
@r6015
GTGCNGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGC
+
2@7860=5EH:2F2)A:G*107(@;%/='F#>E%-F8EF;C)<AD>?4(9>
@r6016
GGCTTTTCCGCGCNAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGNCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAG
+
=;'+)4$B+3-E02&;&;(7>;C,)(@#,4%,A@3C(+C#HE5@9?!<<#2$1-9D'!39'<7'2??B8+/2&%0"8@A"G350EDA0.5??%0"*3!((*6#**G;B9"4<H>6E"50+DC"5!(?H/6%@'<9"'=CBD!!9
@r6017
TCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTNCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGA
+
+%)&?,453E75A/./3!(#"39GA$D!*4*F5*;::=5!+-4!7,EFFG+:@B%*+<=AD26$?3B$<F.(":7>=E.&)A7.*#&4EB933
@r6018
GCGATCAGCNGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCNCGTGATTTCNCTGCCTTCGCGAGNTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGC
+
6?B##4!$@=0.H7/(&+.D3-),#HA*)5@F7F/H"E"*??//*3$=?=01<%=.(28$"'6*1.78G$+;=02@?-()23,26:76E4,:F4;)C/*&EE1H5+$95@3+F9488"0E23(D%#:D,'/6"&D+@@69,B96%)-G/!'"A@A';,7?G/63?!BBAG,D@C5(,#8(9A!==&;.-/#198E$)!:($+*/01::69"-8B(;$&D0+G/H70(A*&B!,DH&))(+)*EH2B"9)+("9:8ED6E3:/G)<D9BA:07.9*4@6$=
@r6019
GGCGCTCGCTGAGAATAGCCATCNCCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCA
+
@':&:,44;.(4&G54A34G7FB$*G2'D5+,'"5=;16)!)&2C8(<(%.E9(3C<@=!'4%;$897@@B2=0(4"DG7-?0B<6A-"=B+:)A<F#1'B47"B0>%6*;(2F)'G??#?<FB-F-G
@r6020
CTAGCNNNATNNNGAAAGCNCGNCGTGNGCGGATNCCGCANNATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAG
+
*'%)'"!!*&#""'('&*"!'#(##%*$#!)"%'"'*&'(!%&(++$("$($!('&!&++%#))#*($'!(+'$*$!($%)&!(!()(%!!%$#"*%"*("()*+!$$*&%"$"$(('($#!'!""*+)(!)&"'#!%'')*"'"""%+$#%*%$&"%#+&""!$)*!!$+'
@r6021
CTTCTCGCCCTCCGNCGCTGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTG
+
#.0G?EE6!1+D*(E>=F/<6DB'A@=7G%;2DH25"F"A<!04'&/*#!F0F&?
@r6022
ATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAG
+
<)5;<G="#0(;,5-6;2#6>+<8!/'G8.*5H"H3"DC7C7)85;!0F1D1?A"EF+,,8DH":+5=D-&//+)1AA'94?H0<%,4&'.=;
@r6023
AAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTATGGCATAAATAACAGAATATACACTCCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATNTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATCGGAAATCTNCTTTGCC
+
?2GH.+,8#=2"0@7&CA+A2GC,'@@+*F<D?2'EB6C**.30EH"*"G17*4""A266;6%2(*:3<'B63-FC*A?E30&G7%<6$96%<FE&?#5121<+)4,8/7<AH.AD#E:#%=<0E.<1:"!+@H(/3362?:6<B"8>2?&CE3/E647?@,C
@r6024
GAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGGGATGTTC
+
"+&&&!!+(("&&#'&+(&$+&#(*'$(!'&'"(+"$+++#&(&#
@r6025
AGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGNGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTACGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCACTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATAC
+
)G(&,.3C:5:$&:0C;..1G85--3A07#:&"&;AG<%$8A;H"./69:@913+E8&HE,4&*B72G:0"%7@05>2F74=@;EH5=F=*=!1DH3:>+';%06#874#E"'$)"$1"E!7!0.D?7+A>,GE=H)12)>.2C:)A@$<G9*(5?F$(*44G7-ED-C=@:*&C*9./*7>*$%G0D2#?C'"29D&'=GA&D@F8?C0G'A>%7/=,(F-*(#9)??*A='?$H2**4%"=?D-(/;H+$-@*70E.#?EA%A6=B,$DA3!6(+>3:***C/2H.2:4G1A+;>1(/D);.4-,F)#(7F7H
@r6026
TCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAAC
+
(++&+')"%!+!'#'#+$'!)!%(#')#&+')(+##)+&$!&(""$#!&%$#'#))"'!!*"#
@r6027
CGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATT
+
!F7%CE/7%86,#F#;0C*A5-;2<4=6!?>@-F?11*8E+1==,3122B#;@'<?=
@r6028
AATCGACCGTTGCAGCAATATCTGGGNTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGG
+
1-:/45H+;:%7D5>)#21':(@$*311"!@(,F>2==8:@%8<&3G-2./<A2)4ED-$616/4#7#/H57(CE,40*"3H-=7BH9(%5.#A)2?97';&A
@r6029
GCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGNGCTGNATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTG
+
2+,)3>A#8$?6=%68%2/.<+0C60.3!;3"$.,2>H<.0E:82-BDG8/6&64H801EE"=1095H!BD7!$'9F2D4C?<509!=<?E683CD;>-?9H*E?)";@3'B.6H-/?108&-7-0?;&%$82>>144#'%08(/&-$C)3*G/:0.9H)3*1$;<6.8C1A>69?*(&B%*A$*><:018=A@F2#%1A<
@r6030
TGCTGAACACACCAGTGTAAGGGATGTTTATGTCGAGCAAAGAANCCTTTACCCATTACCAGCCGCAGGGCAACAG
+
:>40(*#19E(?E'41@1&7&.82B+;CH39::2(,;$C=:7*1"A7E&%HE?/+71:678H;%!)&)*=5=61@#
@r6031
TATTAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATCTATAGCACTTGCTCNAATGCTGCAT
+
?F+!/F3(.&1A4':B-*5:@5-)%)*9%4#8GCB7E8.1-'D4$=<&1('9?(4)/A,(.<1/?#,'',(.;9-2.9638
@r6032
NAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTC
+
%CH.C.(5'=!9163#<;(;=FHF8@8&78)%GH=391"@;4<:,?#?7
@r6033
GGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGNAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGC
+
)G@:"?#7)$6"FC'2<D5#-#?"B5"%1&4D<%=0?68(C;20DCAH410EF7A!+7-6?!=+27?,E,)<'!5,=F*8/7@A->0#&,A1-,/C9"*8$E=E'D,+)3H@#+:"A-F"5C6(8B&?9#8A53;65""(!;-9$1=GEE*(%%6:B$4#.38?;%H3#8.C6H0937#H+!.=F#&"24(<F.3/--96>$D?<#B>.98!57C:%='DD
@r6034
AAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAAC
+
/G&GBD7-64B78E+5/?)?AH!$="%.$?,-::(G4+0=1
@r6035
GGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTNGCCATCCACCTTANGGCTGCCGCTGTAAATCNGCGTGATTTCCACANCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGTCTGT
+
)5;%-,6"3B1)C/(H7$1"BF>)6"%%F>-A?B,,99%.F%E!4H7B#(/!5$";04#/8#9E'*&/)!$2*@;F62%D>-A;>:F>$@A%9A+F@4H!'4-"%A,A=;@6&(?%G%-:H*C=0G!F6;$84=?:;;"2F2#/35114BFE')>&.#="G8(@4&H:06%
@r6036
NAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTNGTNCGTGACCGATCTGCACGGG
+
!%"(*($$+(!"'!$+#$#'++!%+(!)"&$$!+(%)#!))%$$*)$$#!+##))+$#%$)"##'#''+()&"+*$
@r6037
GNCNNGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATNTTGGGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGGATAGATA
+
*$!"$('+#"(+%$$)$(&&+&"'&!'+&($)!&!+))(%%)++!&$$*"#$*+))+)+$$!$"%!'#(#+*$##(!#+&$!'$%!'!!$"$%#"+($)(()!'%+"(%"'$!$+(+#$+##$!*%'"*"&)'!)*$%$!!+&'&%(#!!+%"%"++(+
@r6038
AGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGA
+
9?<$9>BA?3::>))%?(!+H<1<+H-2>H2*9);7585#/GG+A
@r6039
GGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGTCGATGGCAGAAGATCGC
+
>%4DED02:5:E*,9DEC/(4G,EB.?02B!0&.%FG:G:AD.8C5=,1;'('A.>42A262%?3/;5E'(8A:5'796=$3">778+(4BC5;(%?
@r6040
ANNTGAACNGCNGANGNGNTNTTTTCGCNGANNNNTAACTNNGCNNNGNGCNGCGANNGNNNCAACNNCGTNNCC
+
#"$$$"!"$#""##""##!#"!"$#$$###"!$#"#!"$#"#"$!$!!!""!!"##!!$"""!$##!$"##$"$$
@r6041
ACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGT
+
=(1<,3@<&H4"C).F<116;4@""'A08<+,/<('38@;H%3>73$0:G9E1C808B))9>0;.;64&;%=#$8&3%!,2>"0H4-7=5D.236D.F$)&*E/.$??AA.)7AB-1'><.67;3"=$93$>FDB2
@r6042
GCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATT
+
.(5#9!9A*57B8#(BEGB191#F+=:1;<8AA&<0B+2",
@r6043
CTCGCCAGTTCNATAACGTGTCGGCGGAGCAGATTGCGTATNTTGCTCAGTTG
+
,E9#C(3-15<*?A5?H*6D4!!GH(-'7>8)<877**!.5A;!G@/C/6*=*
@r6044
GTCAGTTATTTACCTACGACANGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAG
+
BBF948=F./G"!1>5H(-?%0;/F9'=@!'">-=54;0$17312%%&2$.B--G?36@,4#)":-F9?67H6&."&>G6G;#+7<$E$';5'>5*91'GCB9A('"$00'(@D<3-C)#E<B"!C8)F@&'!':*19;:0&<*4F@(=G$6A:*;4*/
@r6045
TGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCTTTACGTCTTAATTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTNTTGATAGCTTCAAGCCCGAGTTGTCTTTTTCTA
+
&0G-</6(?3E.34?2BF.&9-*@@89G/A57CH?8"F$%!;3B$E#@E1DDB(.6*:G%6;"E%061;7:6"$,41)*#?D#@$.4/E#(,6>#>>9,7<EC.,<H0;&(!4'.*(?A5"5'6-2#<6E,$@0!FE2,':9,%=&;7++1C?"9?.970CF=7
@r6046
GGTCCTGNCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGNTGAGGCTCAGAT
+
?379-)2G:>D.B:F@$7>#CH%/;.:3>/%5;/&C&G"8<#=E&%@4&*@/D&"94>"FH(%/#-&0=9:B(#.>>!E1HE&0."D2=6!(%B;!;F;&+"
@r6047
NAACAAGACAGCTAAAGATCTCGGCGTATATAAAAGCGCGATCAACAAGGCCATTCAAGCAGGCCGAAAGATTTTTTCA
+
!)$1<*#0&8D*-%<5(@!C3F>6F*+E8,.B$*$>&FE#*-(*%(83D:.+(:6>?G"5&%1$)(25"2>415$:*D6
@r6048
TATCNCCNNACTTNATCAGCCAGGAGTCCCAAAGAATGGATCAATCACTTATGGNTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGGTATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCNCAGCTATTTAAGGAGTTCAGCCATGAACGCTTATTACATTCAGG
+
$&))(!'"%)&((#%'*+(!$%%*&)*$*'!&!%+"'++*%%'(#'%)'"''('+!#%'#)%$((&#&%"&%+*)&'''$!**)+!%+&+&($%#")'((!"&!'($"+()!)$)$+*!#*#!&'!%$(&)+'$!!)!!%"!!+'$+!)'%+#*#+%%"!%'*+%#*$#)+*()$'+'+$!"*($'*(*()++"*''*!*#*#%"&#&%+"*)("+#&$&$))!!+$)"%"*"(+(+$&)!+&*!+)&+"%%)+())'"$&(!""'"%###!'##
@r6049
AAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCT
+
+"&)%&$$"!"(#&*(%+)&%&'!($(&%&%&!()&'#+#&!&)$&'***$!!#**"$((
@r6050
AAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTAGTAATTTTTAGATGGAAAACGTATGTA
+
!E?FE')B@3%:,<%9EG<.@C+>>7614-H#'B+1C99<G=E'B9=><19#H=*4,4C?6H!B=CH@2#;>#'2:"6CA1@:E
@r6051
TGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGNTCGCCACACTCACAACAATGANTGGCAGATATAGCCTGGTGGTT
+
.;G;F0!@$@B0@%00"F2(28E=@D&&<H0%)A9#/$F0E,7;9''C$AB4?'>=>99?%06<H2@+=@:&<,(?HE902(59"-"3%HACEA,9!74@#8G1
@r6052
ATTTCCACTTTTCATTTAATAGAAAAAATGCTCCCGGATTCAGTGAT
+
.<-!=4;26C#<C'#-6'0D*-6)$9C6+)E8<=!6&H-(@5=E;B(
@r6053
CTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATG
+
.20#'A02&%9E-<(*F<"*D:*$-A)#DEB/B6"!&+#!*@1:91=
@r6054
GAGGCCACGGTACTGNAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGA
+
-@F3B@#?,;$C'8AG&,HE,A-%!B.D9?">*@%@627CH+"<H9"51<5).D#85$*E%&>A?A5*=$G)B1$E7B@D$:&-?0G5@A8/?#C0,1+;C-2AE.33@$=.52;"4'4C5!C1;17?8H4))3'/F=D!)<!HF!3D<C$,<0:*&>#F?#G&6F
@r6055
AGCGTCTAAAACTGGTAGATAAGCCTNAANATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGANACGACNTTTTTAAANGACGGTTATCACATTCAAACATTAATTTTTTATGA
+
1HA)5:A#C2)'"04D@H4/)0G:&0H55$B/&8"H58?53:(D8'(,)3*&@F</+D7.70.>)::,H6;%+"A(AD1=:(.4+&@E$.5+C"6;F*&'99#18A!G8+<,F!,(E51+C"%9=/G36-
@r6056
TAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAG
+
.GF202,.9/2+?1FF7)7!9G9$6D,G%3*@!4/<>.5)#%):*1B;!E6H('A??9.%5,A8)9
@r6057
GGCCAGGCTGAAAAGGGCCAGGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGC
+
*?H!$06??C.!5)D<.=&;40,/->FBF#=F7=D9'&!$650;D<(.)+%2*!.2C<G/-7/A:9=;
@r6058
AACGAGTATCNAGATGGCACATAGNCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTNGCCGCAN
+
6A*D5,E#D3<7-/%9?C6')6'+A+-2?8-;G<F<5+$:H882E#0./+$37=,<+29'170(#1FA/A$1'/370</%@H;@1D@=@>4C&22DA'
@r6059
ACAGTCGCTGAGCCGACAGGCGCTGGCTGCACANAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCA
+
B3=?!B>;$A36A972@"D7"G/*8+1=0H$7')!@&)=$=@"<DG2H$%1-$=G@4/%&F945;45E*=H'>,$2-A+'E0!)2(:>628!?8/$&-6>9%46=$//-7FD$H1</7
@r6060
TTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTNCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGC
+
3=H'4+35>8H#2:AE(HE>.8',;)0>'4H=0;D>%>-1%91H78"B<<2($?+CD2(61'!/316,#$,2"2:A+66H,722?*G'"BG:>D5#G$8#-C8+,:HDA%F>B59.3>+9$$;AG?A8-6@&)D/D-D(/;,.=*G;3*,+&@+3$'"!5%=/'-;'(>E=;2B13=F(@(($(/,C=2@800:&@(*<1=>06."01B:7>-7"A.B-*09+-C*3A)2('#01",!,)
@r6061
TTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGANAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAAATTTCAT
+
@!2-+A1=GE(*'E5@?3=E*?E389!0:;+/3$C(+:2G>,6H2"-<,%.A64;C",9;0(6<?H#%EB'0%@??#>56%3.'+&A%.!!1!8"56'H3-A,3@;-7E#%49$#2H?$$!&:E%*6.3FC3G12#+.-F*"E46D!/>)==1.BD;AA,*7$/9*256-*%>'/!
@r6062
GAGGTCTACCGCCCATGACAGGAANTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCGT
+
FAG$FF"/;?,*5?:(!=*--C%C.>(>0>>-:3:$#A16>G5AH<=;331<A1>603.+&E4>!>$%:@5"/"#5
@r6063
GCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATNTACCCCAAGGACCGTAATCATCCGATCTGCGTTAC
+
5;F%:D93=GH%A>H7,E7E2=3&/%">>%&5>1C7'.%G1<@$3?57B(64G>47!41,4F$#4$45>9DA(,=/@84
@r6064
TAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAGGCTCTTGCCCATAAAGCNGATGAACTTCCGTTAATCATCGAACTGGTG
+
;,:?21GE%@/!<E=AF2&<FE-(&G=A4E0.5.4:(F9G%D("&)*#!-;94E=E')085G1BE5A(@7=1''D4#BE8?C24D>62AE6D5<.G;2&3*,3!'8G0;+1H50A?7A
@r6065
GCNGCGGCGCGATNCTGCATACGANNTGTCTGCGGCTCTACCATATTTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTANTTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGATTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCA
+
$)"))!"#'&$#'&$&"**)(!)'%+'#$&!(%$)'#"!)%&+)$!#!$+!$(*"(%*""!&+(*$)))%!')$'!(!#)&'#'#**'%%!*&$&'+$%")&*'#+$#+!**"%&#!')+)&%%(%*#(*&))*+%!#&$"+'!$$'*)!(+'%(($'#&"$'!#+%&)*#')&$'**%))+(&(+%)!+$%*+#*#%##"#'""'&%#%&*+
@r6066
AGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATC
+
G%?'!%7<*8>5*=B;6%-,G*F%>*&"H/.48:%=G6HD03B9C:E'?E4*A!*A02&=5=#F<'
@r6067
TACCGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGC
+
%#(%*+)*"$+'$#*%*)$*#'%##+&!+$*%)$*!%*&+$($()$++#!+'&#"
@r6068
GTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACNATCAGTTCANGACGACGCAGCACCTCCGGCC
+
+)*)&(%%*&&"#+&**%*#$%$#'+'!%(&%&)#!##&%'&%)'*'*(!!&%(!$#)!"(+()!&))'
@r6069
ANANANGTGATCCTGACGTTCACGCTTNCGTCCACACGGCATTNGGCAGATATTCCGCCGNATAA
+
%#%"*$+!'*+%&'""*%$!*)!$+!$*!!!%')&)'+"*$+&&'*'+%+)*+&+(($'&)(+"!
@r6070
NGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCANAACACTGTGNTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGNCGCCACTGCCGG
+
);<81*?E?BB+-D"H*H7!*7%E?1!H2?''&,3,)9168;81G7;HA4C)&A)B:>62'E$,H@E-@>,<540EE=4FH@"4A"=&?8%H+@&*!!.3%#76*'3;6EC48-=!=(6$!<8,C'/8!G?>$0:+8G'=:/1G"4E:17@9;:6,+!*:23!E+8".?*?1?".E%G>;:EB7A?
@r6071
TTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTG
+
C%62=AA6&)18C(&417:F0$B/*>@+-853!C1GB2.0-F+677&3/)(EF,6=*>(!E*-E5?'1>87-DEH6)1G;%<93:82@52-)+%;<#B5
@r6072
CACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTGCTCGCACGACGTCTTAGCCACCGGATATCCCACGGGTGAGCCGTGTAGTTGAAGGTTTTTCCGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTG
+
9,)23/8<0+-2-G?.<)%F5F>(3(H!7<CD?==+!72/)2B+8;B54*?A9(#(8093)5:!DDC6>$@-E97H!?A647)AG?3E;=54-C+C8$+D/1<F+>5#+(=+)+)1'C>:E0GC<7=A$"8#E(/,D*C:FD'(+E1351(69"-E%63CD.?G.:;@=-C,*=F5$
@r6073
CATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGNCAGAGCACATCC
+
9,:&#+F,5<3>:9'C2G902(<G@/&(9G=@)<BCB4&;H?#(!=1"!E!G)2(=%G&=B?)?,F57(=HC':2+=*:34$$@H21<A6D;<&,%%D(=H92&54*24,)1-9#+5''1/H@$1BF#21&2G@!8E9'1
@r6074
CAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATNCGGCAGGAAACACTGAAT
+
)@/6$F-HF(,.$B)F$E-*'$;39&<1G'AB4+A5'A75A0/$*&%9-F&G"&D1;%<6H=H,%7"+0;3%=15G<A#2@-=7G+;E'0$83;,@A)#0,5>6E1+8+1#H%:"7,<8
@r6075
NGCTGTGGGGGAGAGTTGTCNAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGC
+
+(*(%%!'&+&('(!%($*)#()'%'"))"!+")"##!+&)+"$()''!$)+*%*"($"'+#+$&"')"&
@r6076
GGTGAACTGGAGTGACCCGAACAACGGCTGGGAGGCGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGG
+
>-)4B;5?+9%7''86#9$G<G*@0(*2?8"+?*)<E<!8DH=&9<!E")601)A)3;5,*3D34*&>-6A#BF:(H7>*?&-=?A02/=&)-)4HC"C39D@214F-:9(B$B)/=7C,@3:%.CA"F",41(.88HF8D)&7+'8==%,1B5;@1*>$!<4'+&#>8A&6FHG6;FCG;@8<963D836%D-;'(HBH"*+9DA-(<AF/@="$B*15
@r6077
TTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGG
+
>0);75:3A">=;9-8/0<D#E@6,C98.E0(%E0<D>36A)+&0)@?!&'D9:DCE#C4H?A78
@r6078
ACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGA
+
#+'"%")"!$!)")%(!#($!!*!!$"&'+)%'#"'++!(')#!")&$&(%$)$$+#%'$!!!'&&#*&$%!))#*")*&%""'!&&""#"!#$%$*+*#*!)$(!**$)!)&%%+%)*$&*"+$!#%!#!'&(&"%$')'#*#
@r6079
TATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTA
+
H;@HB!>"4%&8D&:H)49#F%9#(5E>6%>F,;H!F!0$:G
@r6080
NACCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCNTTGATGATCTGCGCTACCTGCTGT
+
'%C&CC/9%9D+%:>9D82,,3;":8>(!39@(-=9)7?$6#?!1)@$H3"=06"#@'1;C(@E&E&$@?%/,2#:3+D+.0,-5614A9+3/?6G*)-(!!4.D-:75C34)CB,1?&?/+<:5"/;D!
@r6081
TGTACACANCCGCCCAACTGCTGGCGGCAAATGAGCAGAAATTTNAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGTAAAGCTATCCCTTCACCACGGAGAAAGTCTTANCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACNTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGAT
+
)+)F=/<2<("(5A2+3*)7!'@&!#C0H!)/F#/F:&*6/(01/E4/3?E>G/%1)+??3HB:,5.H<3H*A48;E!":H2+G-8:'A?+H-&G=54G7C"G+=,,7*?>,&3"90)**,G73H(-+;81F5G<,/24#17&&34@=/;6(2,=EF$*29552#68E';C5G('$D5E%)E/;;<$?!!8F)=>@:9&A'+H3#>)>*.:76;/#3C?+=A:(HF07BB6')G;'0"+7+614&D,F">3@A&&6'2
@r6082
NCTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAG
+
$2<=4;3/?6D!(,'BD:)"0!05?<C?9AF@A/)?C7-D4-B0!$7F
@r6083
ATTCGTGCATCGTCAGAANTGACACAGGGCGTAGCAGTCAAAAGCTCTTGGATTCCTGANACAGAAAGCCGCAGAGCAGAAGGTGGNAGCATGACACCGNACNTTATCCTGCAGCGTACCGGGATCGATGTNAGAGCTGTCGAACAGNGGGATGATGCGTGGCACAAATTACGTCTCGGCGTCATCACCGCNTCAGAAGTTCACAACGTGATAGCAAAACCCC
+
$E;47A23=C%%,3)72+AG,G06!*;48><;BA08"27(2=574G96+%35+25D?+>-%=!&5<74F6##,,310&""%&79G86+F=+=86+,-3G(A6;2+F-"!&7!#!10+*(HA:8G.<<FE29?C/@7)'F2G%92('>09->;7.GB+<-?,?2'!G13?9%.6H9=0EB!$D=95'*"-+B?-;@.8DFE=#7GF.&5)?"6&6?A#?C*H1"
@r6084
CTTCGTGGCATCTCGTTGAAGACCATCGGGGTANAANCGTCTATGACGTGGCTT
+
$'2EC$D%B!D:B3<1E=1()#732?%H0,<G:5FG0*8"09:':?6(A+@=D+
@r6085
ACGGATATCACCACGATCAATCATAGGTCAAGCGCCACGCTCCTTAATCTNCTGCAATGCCAC
+
<F>4$!/?88(44A0$%',F9C>)A:'D)$;7GC&BG2$6-CD4"3,3CG0$8HHF=-2(8@>
@r6086
NGCCCATAGCTTCCTGTTTTGGTCTAANCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTNAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGC
+
"=:2@EE/6@:&E-H=+64<):'B$%E=;5'H.G)"8#;BB))#;B%7F*A;1*C$/F*>C#E'1,'%45*,E3.4/1(CF)%2#!?'E2'($<(H=3"GF"%;!G930AC4!?DD!6&A*A2A''/>AH..0'H"05-"".B8E?:*'3!82A.<1B%:1B,,E:#@&>2:#AA*6F?;1"$%?/*F+($=$$D=1;@3?$:A)2AB/3+2;=*
@r6087
CACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTNGCA
+
''>72'>2C%!7?,.(4;)1.D.BA?>HH<($%2)-37B3*3*"%5>0$F),;1E;2937.5B87-<9/-#G
@r6088
GACGCATCTGCATGTCAGTAATAGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATNTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATTGCGGTGACT
+
E-3::9&#%C++BGH=&!A:A/H><<)%GE'.-B"-160=5:)C7-80BH6727CF%A;1$,0$;1+,*3=,F37B23B8F1%A:3',!(2@>103>*@>%H.8(#,.1'%B2;E/-2E".%9:C=8"*%206A@-)D>A/'@!H%#2@DE=8"E2((--&)>D
@r6089
GNGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGNGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACC
+
')@$'GD&!1>&H3(C5;:?$5;,E)#)3$&,A2!/%88)-.&=C&6BE><5FB!G7E"7:D>8B=?GE&E,<C@.&=9H+=DG5/-&A#,/D&8.5+#&>-)F*=4>"$8
@r6090
CGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATG
+
?-;2G=C-)5)817>FCFA12:@:78/&-"H-5?8$3-98@%5#
@r6091
GCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCNCCTCCTCTGTTGATTGTCGCAGCCCGGA
+
HC?3;(+!01BAD?&/C53F2F!$2+#+1H./.6#/G"!=:"=F=CB;/CBAE?D4)D+@5);:*56C88G''#=09HD7,3;H.')?(9F<G"1#*;D"2-,=<(D9@D$,"?+"A,AH((0%2+F;$DA@H91*?+4!H6F4*4
@r6092
NTAGCACCATTTCTANGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATNAGGTGTCTCTGGAAGCATTCAG
+
(=$0B0-87#&;91%19GH,A'?A.2!6+A?G2??:7E'H15(0@6C*&D>53**579=;$+.(%)5,-:0.;A52
@r6093
GCGAGGAAAACATGNTGATTGNCCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAANGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTNCACGTGTGTGAGCNCTGCTGCGCAGAACTGATGAGCGATCC
+
"A,)2;%6+61E":H6G'*'F!*!D39$D'$3%51&:H)$$6?5<.<H)DA$$4*,>H.$#+0-%6?,"F$"B&EH.5B4A(#B$&-:,,05H?)93&#:(''G4$'D'=?8B6,52>E4E(-(!7E3G:*7,.3>'H-.>#6<%'-<
@r6094
TCTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAA
+
#*-6*A2""'<,0'4D2+-D2((&4BC%@C@C+#;3A,/H?A;D52=:0=56@B=8&A#F;(A
@r6095
TTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTG
+
1#4<6$C!13)FGB"D+$;5,#030;48*3>5D&5'?7.!B)9-1-A6>=$#,;.B:"DHEH#,$2,/D43?@?(.%&!
@r6096
AGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGGGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATNAAGACCTTCCGCTGGAAAGTGA
+
2E@GD,=%=B9<%9/&"0!,)D8'.2>92B5CADB)F@")D,B#B4AGFCH%857A@!8"BD)+=+;-92+(;96B!#HA47GF-6'))#/:#7-782E..7--,H@7G"*H2371>*)$22?F3;1A9&&B.@
@r6097
CCCGNTNTNGCNGACTGTTACACACTGTTCCGGGATGCNTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCATTNTCAGCGGCACAGCCGGGCGATGTGCTGCTCTGC
+
)!*&$%$""%&%)'$'*+")$(%++'*&#+'#+#$**%)'"$#!$+)'!*)*%!"""!'!$)!"+%$%!#"'%*%%#&*&$''!&&$+)*%%+%%%(((!%+)!*)#)!('#%'$*!$%&#"*'("!$&!'#&(*)&%"*&!$&(')#+'$)%*#'*'"%'#")+#('$)%&#"%)"*#&#!+#&!%(!
@r6098
ATGTCAACGAAGAACAGAACCCGCAGAACAACAACCNGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTNGAGCAAAAAGGGTCCGGGAATTTCTCAGCCT
+
0!*3('A=5#5-5A)2%<G:;<D:!9?+E=1@:%B7>./9<7<$2!"C'DH<F6:(968=8G,33767;&%+"HFB(83@-%:83G92@*59BF)B=@>C/,91=AG)'(+A&);,HH
@r6099
TTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTG
+
'5DB&&?=4+80".66H%+#E"$?A67C7DFA42C1->D.&30!&-F"<?%9=+?8B.%,.!9D<+BG<,FH&4C&.
@r6100
NTACTNTAATAAANNTNNGGGTTTNTCGGTNCTGGAGTTTAGTGTTATTGAAAGAGGCGGGTAT
+
"(%#(&%!%#(&&'&*#&*)&'($"*%"&'*#(#%(+)**!+(#$)'%'#&!!""&)$%'&!%!
@r6101
GTCGCGGGTTTTCGCTNTTTATGAAAATTTTCCGGTTTAAGG
+
#6HA)=#%=7@8=)@0C,-*<4(#D;$3G/093'9>$*(:(>
@r6102
GCCTTNCTGNTCANCNGNAAGGGNGNAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCNGGCGAAGAGTGGTGATCAGTTCCTGTGAGTCGACAGAATCCATGCCGACACG
+
)*#!(!('"$)%%!($%!!((##$''"&+$*)*)!*&)!(("$&"*&!)%)"%+(*$$*''"+%&")(+'("$)&))(*#"&!&&'++!'+)"()(&""$#()))#*)'&+)*!&(&+!+'(%)#+$"+'$"+"!$*&&!!!*+)#+")(("%%$'(+#)$(&""#"!(('$)&
@r6103
TGTGCNGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGNTACCTTCAAAAGCGCGCTTCAGTTT
+
.A*%+&*%&#@4E89>%4',.#-H)/)B/$=:0=4B"&7E2F>;$D)==2#E,;%&!=9'F2A:,*?
@r6104
NACAGCGNGAAGGCATTAACGCCTCTGCCCGTTACNCGAAAAACTGGGTGACCACCGGCGATCCNGCGCNTGAGTTCACCANGA
+
+?'?D%:$853".;,&E&(?#:3F>2>><&356.#G8<%E#-98F#A.&A:<;/-6@:?+42F:FG2<#D;53-4"6%+9(*</
@r6105
CTGTNGCCANCTTGGGTGNCNTNGACNCACTCCCCGCCGCCGCTGTTTTTNCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGG
+
**)*%)''!&$"(!#$&'&)"*!*$&"%+&$'((("!!#&*")%'(#+(*&()")'#")%&&&"+%&#&$*%#&"+*!&!*)+&#'%+('&&"''+%(&"*!(%(!")%(###'
@r6106
NGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATG
+
!FH'C0?%94/@<F<<>8=*%,#"D&)F8$08!?8#C#/+%/-+86"?#=<:.?2+F>@*-!:A2</*5&
@r6107
TCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGC
+
@*E3"$HC<.2@1%6H6#1BH"?;;$,1/(+!5+(8//6;:7*;*D7='48:62
@r6108
CGCNTTGTGATGCNTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTA
+
&$&#%*)$"#!(*""++)""'(#)("&)&&!#+%")+"%(*$#&'$+""+*)&$)$)++"#!))''(*%&!)$((*&#!"+"#!&*++")%%&#$"'!'''(!&&('(&#''#+&$+#'#$*'(&#"(%+!&")$$*')$(!")*'"$(%(+*&&%&!&"*'
@r6109
CCGCCAAATAAATTGCGGTTATTTTANTAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGT
+
)BG$0&3:3H17-&B<5GA?93,'14G.802D*%)8)$1'#ADC@%&B741*/237D)=3)G"0B-7AB*)#)D54D5D$
@r6110
AGCGACGGGTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCA
+
0-="24(C7A/5.'>A(6-A=;"%>".2.$H0=>C(1::058."5>->)(66AG>$=:31.9A(#
@r6111
TAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCG
+
5.G;)-8%H8G+%(=4"+<:7F=163-:-02B))%#"4269"=,.+G-9./F$D?$AC6,D.@?(%$*)9:E>958F"@)5/-3%;'0?=:EF4+#:G&
@r6112
CCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTNTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCG
+
$=E,'HC5,#C@(>HH9@FGD/11(<4$"/A*(/8&/0$H5#.'B,#5"5-4H$>2?'*8'F0659C!87=(@+C%.G$4%.H)E;E%+:C6&G1)G4;*99E@8"!')=99!9:'+D<6,7(*?:H$3D;:E!;?,9:2/(.20:::)F,;
@r6113
TNGCTGCCCCCCATGCTGCANGGGTGGCTCCGGCNGTANAGAATGATCCGGCAATGGCGGCANCCCCCAGGACAATCTGGNATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGANTTACAGCGCCATCAGGCANAGTNTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCGGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACAC
+
)!"+*)%"#+)!*"#&*%"'+++&''$"#++%)+$(!(*)+$'))$&()+*$+#!(#"#&"##)('!$%$#(##&))#"%#"'&*)'%!*&%#%'$')))'+(#+)*$*'+&()"&%""!$%$#+'$!&$"%"*"!$*&($)%'+$%+"%#%'$!!%"!("(!%#+)+$"&)!&+('#''#)"&'*)%"$%%#$!%$!"(()(*)"')&$'!!"$%*&#*&$')%&*+'#(!'!#++"+'''""+"!!$'$!!)(%%'")!%##!("&#*$$#"+"'%)#"#&&+""!!'&
@r6114
CAAGCTCCTNTNTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTT
+
118G>.?>!A,F02#1@:9.5H?/9BB"-?C1%3B8A0&1.+0"H?
@r6115
ACCCCGGTATCAGNTCATCCAGCGCGGCTGCTTTGTTCATGGCTTTGATGATATCCCGNTTCAGGAAATCAACATGTCGGTTTTCCAGT
+
1H7),.9626:39,>,5D%.!G&EG#;:9'GA-2/$B0??3',G28G#;+4#?*3A!=C6@B;FB?G"9?7&5#33'<G(-:)--=C$*
@r6116
ATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCG
+
HF&31#&+7,#3EA27C"'D=+5DB"A<?#/6=-51G73A-&B2DA@9+F?HE9+("A=A#HFF($':,99!,A)-#@DG".3!3DC;@"GFDE3H80.35.
@r6117
GCTGGCTCATANTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAANGGAATTNCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCG
+
@?+E,8DFG/F!?*(+:@#.<:3/&9)5>)/@)@E$=CD;/D1%%)?C?,7)G00E:4FCF0%/%&!&82(0#<1$',!9D)BH/5.9CD"5H1'+@''
@r6118
NAAANCAGGTTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCAGCTGNTTGAATCGCTNTGCATCGATCATTTGCAACGCCACGGGGCC
+
"*&"&#(#*&+"#")%$!%%*"!!'&$++"+$+#+'%!""+'#"!+*#%(#$&""#")))!(#+*&#'*"$&&)%%#!+++*"+!#$(%"!)*+!#!&$*$*""%'#$%#((&&"#*$*'*#*$#$")"++(%)+!"(&)*$)&##"')'$#&%!+!!$(*+)!""&)$$%#$
@r6119
CTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATANCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTNAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTA
+
28/5>3=9?B-BB%**72?;&;#6F>'76:G0AF?;(:0;-D+359>0HDB$*+EBC->A+A*"6H>&'5"?;&9!!1$.%(E%8!#(#"0.?H.,78':.=3A@$)+.0.%4*(;:.?$G;&5>;CGG2E$#.909DGF6,.,'./2/E3>)
@r6120
TCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAAACCGCGACTTACCATG
+
@D/9=:73%>(#H$0A/9??(E1B&G%G2.(3*"+$")%(>0C'":B,3':8=9B@-DEB>&*=<6(%%>$A-A6+#8#GA5-4)-/@=D"G'A81
@r6121
TGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTC
+
/HBC1;/-::5H>=+',A'8<*)=BG7>'+F1):9/B-5H9@$/98-3:.)EGH62H"5,!"%*:43A/7&#,G*/:<G0>7.,>&D%1*93'
@r6122
ANNNGCANCTNANACTNCNACNTTNNNNNNNTNANCCNAGCNNGNAGNAAANANTCNNTANNN
+
""$$!#$$#!$$#$!$!!$##$#$$"#!"#$$$#""$#$$""!$"""#$$!""!$$$!""""!
@r6123
GTGGACAAATCAAGCGATGCAATGGATGNAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCC
+
48$!(H3/E6.(#-A-%7E8FD4*:B35'#,>'6/A!<(H&H.:/7%;)HB8*?!"8A@"GE&41G8C3+F"A)A4%:HE5:+=?#F!ED?G8E@,6E"7/600/,B,58?>;&70E1"7'.$"5B&"62?$!3<=57,<="%?*G;8HG,6$-<A,7D$3),%/<5CD5$D9'+1>7
@r6124
GNAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATNGNCCCGGCAAACGGGAATGAAACGCCAATGTTTGTGGCGCAGGGCAACCAGATA
+
("'+')**$%$&)**&***$'%&!")('#&&$')$+"!""*$"(""**#(!()&!+&)##$"%$$#+($"($!%&"')#!'#%$+""+'%'#)+'(&*"'&%()'"(!(
@r6125
NCTGCCTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGNAAGCGGATTTTATAGGCACGGGTATCGCCTTC
+
"%*'#+"'*'+*(#+"&)&%#)!&*'+)*%#"#)*)'%"!!!$)+$*%&%%!&$)(!#%#+"'%+#)%!)(#$$&+*$"'#)#+'(+$&)+"(($&*#$"#***+"'*$($*%%#$**)#**''"!'*)
@r6126
NGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCNATGGCGGCAGCCCNCAGGACAATCTGGAAT
+
!A2EBF1;C+62-CA.%1C%$'39?H+)498/-/E!"@),F%9.&53-%D&:D3>!/?9@>%%+B8+(%C=@A><CD$?*74"*8$);6*:G')#+:G<B5,,8;!6+#'D*;"+"</'E?@E#$46"2DEE+&FE+B?06$D$*H;+'001"F0$8;/E<>C**0)F63"D'$+<>GHE)F62,&A'2
@r6127
TCANCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCG
+
@;83(')A<?!75@!01#1FCG1A;G&9#9,!0!3(2@A90?%?G&"-A'!%%A%"<")(D(E<!.)7$(@?C3
@r6128
AGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACT
+
&B%E;4,))(,05.#7@0&+>.*6%,449G$!49C>7A/A&//C/-.3.0B*@"F,D';@&>7DB+432!3:<=?*7%;*B93B;.=7?G3*%E=>C?@;!*!/:8=-F
@r6129
GGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTCAGANAACCGNCACGCCGCATCTTGC
+
6'F";E7AA$&8@8E5!&$D3FF#::;A3-#->'')F/</2$$"+6"A6$=F#C$6;?!-)!G=+
@r6130
GACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAA
+
>;!+0.HD+$0@G52,(.&1<'4'C2E#%E"<C.4G@31'*98"3C'E5!8-5DGE2/-"@-59%9>A3C:HC?FA$=%(H<B=C0;1CH-#'H$1>="20&7H3@$)+H6B=32F&2(9<A'BF8'B'.%1?*6?
@r6131
CGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGGCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTC
+
+.+,>!)GA%*>:B5997E-H0679H-:A21-!3((0")4.+AA$=$!#(BG.3D;%?8)#@;**B0@#'9;6E(&%%B6G561-;C*+$>.F23B;,6G!(33*79B=@:;%(.,%-C8&H*)9.41,:0=&;>:'
@r6132
GGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGNCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCA
+
@2H$&"("E13A4%F324+G,%?$4+6%?B(B7&DA%?,$-@)=02BD555E4(:&@%4#@FA0;'9C*2=&@D&/'C(D0==60:3F)6?:*&-*3492%<+"!ED73D$?;#$-1"(7:'#'>#C,=34"A5#+@0((<-HE<#%H6=+@)&2C!F155$/2//*"#H73%$4H-(!#>+'/5F'H4#$H1?
@r6133
ATTAAATTAGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGNAACAGAGCATTAGCGCAAGGTNATTTTTGTCNTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAG
+
<G*1E66/-E02@E$#0E7:E=*6F37%'B+>H$,D--F4(=))A0A$FE/+!/&0=':!-70":73=H%'B4%D,>2;:A,3F=6+5/(<FC?=/F5.'B-8#454F;.)B,<#H$0#&>3F$18:%D4!3HCDF'>C9"BF&9DC$DF:!DA0B&5?"E"F=,7F.2(?5/FE0+41
@r6134
AGAAAACCAGAAATCATGGTTATGACGTCATTGTANGCGGAGAGCTATTTACTGATTACTCCGATCACCCTC
+
BH(2D=#%1<HB!/")$.@&2!*C?@"%!38E:G;,GA(16:.6346*46$!50!4=+,9+BC9!G(60+21
@r6135
NTNATTNGCGCANANNNGTTNCNANNANNNACCNNTAGCNNANCNCNTTCNTNNTGNGCNG
+
"#!$###$#$!"##!!$""#!"$##!#$$$"#!!##!$##"#$!!$#""$!$#$"$!"#!#
@r6136
AGATATNGGCCTTGGCTTTATCTCNATATTATNTGGNTCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATAGGCTTTTCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAAC
+
)%18?H.9DC;<9F!7*F@?,1=-9B?#"G=D99D32'<G1=<9DCB-,:"-9#";HC)G=1'*!!H,:>/+";%7#1G"4,:D)01(E="-1*:G424-E%G)$:#"-6B4H;C&B5"D.3<8G>%%D/5E(?."=G&'#!B!;
@r6137
TTATTTGGCGATTATTATCTTCAGGAGAATAATGNAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACNGC
+
+.2)*D6)E%4:80AD+E4/:2=8/45@(3;?$B9(04<C)0')$;GB#-B4'9DC#55.3+!*F<0%&3?71F'<
@r6138
CACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGG
+
>)B,'.:!'2*!,E+7E8*A)8$1:6>'A*;1'HFE*F@@D;9?=;H5F(+-?898&=.@,4;!CB?+="(*0@"98/(54B?9*"?G&H6%)C()9-A'$+(+)3%A87+;1C11#2<7&H58?6@'G
@r6139
CTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGT
+
B<A3<:*!C.!7;%*>=?0/0GH&)8G#A)35)7E*<-+,5#C27&D.!)CG$H0(%?B,%,=>/C@)F?DG;!-D3(7':&466>:.H&#6HA7B>?-('7,3B7D)#7EC#6>/H65=&?+
@r6140
TCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAANAACTGATAGC
+
A;.5A%G7309#"H!'!:2%!C+B:+?8/;=*H"08D8,GH/8(HD3<
@r6141
CCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTNGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGT
+
821,G:%#>..8;-*011*42)60&=>*:B3-;@H-"G42:C7?+,+*5-*+!H%&=!A>;//77&?4!.4CAF5*@%"'>.087:G.1#<A@0C+(562E/?.7F279>/77=-,$&+8D&+?!(5573$2?F*@0G47,&F;'$B0?$?G9ADF/.##2<-5>45(?HE1'*H.5D=&(3<1F&4:
@r6142
NTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGG
+
"A,1=2*(1=G)&E275,H+/(857"BE&*+*$D)&/!"731%,
@r6143
CATACAGTTGGTATTGGTGCGCACCAGCANCCGGTTGTTATCGGTGCTCA
+
'/25=9+4@2C>16#,4A->8@B6?<C./);3)(G@-F>HG:;,$7%5*"
@r6144
AAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTA
+
5HB"A-/281#<H#1/$4:BD,"(@%;5=#><C;-0@A/+:7D-01CC1"!/80HG:<=BH'$9-/4
@r6145
AATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATG
+
)G7G>;H*0/E+C2?;&BB"!3:<>4B>)D06./04?',@/93EE>%<AF.7/E2,'
@r6146
TTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATGGTGGCGCTGGTCCACAGCCACCCCGGTG
+
6)"A)=-*-7$1($D$?=<-1@C0H,@28H,/E,")2%-<4<7!*:8>B'3F:B45E#E=%$HC3,@'&203%=$;7AE,
@r6147
TGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTC
+
>="300(EG.'<A"H"?H7&>H17,>(1@;5"0#$A7F:":E.#.<:;+&5+*))GB'7C@!4?;79ED<%E1(0!F!%H>HA)<:C+.'09'29#7'<3F?67;<F%$A%421+=C91"-FF"D>.@3E?"!;%7-7B1'.!&"9BF">.A%F);0!H)%&!:!">7&2F#)AH+**!@6D0;5.6+<.8%<4(6+9#E8-,#G%2)#10.G5C;96)<94E(9
@r6148
CCCCGGATGTGGCNGACATGACGGAGGATGACGTAATGCTGATGACAGTATNAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTG
+
#1G#6%H;*E?%8&;29E)48%GF!A=<C#E06<82!5@#+73(920<5@+D61;&.(!)F0CB=D&'2,/"+(!!$"*@*G,*,9#&G>2'$/%<'*E''>,35*)G1
@r6149
CATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGG
+
(.F%!20(;+(E4C'G/@!A4"5:(,%H"E/?47E333(A66/D;1C>06!;1%9=,%*-89=8D(B2$C(25F!)7C56B/?$"
@r6150
ACNCNCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCNATGAGCAA
+
"$"'"+($$*$%*$#++)*''&'*('")#$!$#)!+&#)!*(*'!#&%#())((++"$)#"*'&"*')%(***(%'#*)*#'%+*#""(
@r6151
CCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCT
+
87!5<&:B1@2&?34@FFD9-@3*<EC;8935'0.<2&3%<<C5=9@=6"F.33!9G=@6"<$D14.37'+2F#EF$F;<(55;6!.A%26B4F-G:=)#A"D-+>F;<1/FE=</&0<)95/FB&$(46H(2#H%"3&(4$2?A5@DG&$##"4/*8=@-8>AAD9(A4<D/,&'&:.1'(GC(B$*4=H;6HC6#6#9/'/:2&7
@r6152
CTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACNCTTACGTCCACACGGCA
+
FC:8F=%0/1E=7/?'&$H;.":8EE;+B=671A(5/&FG*A.?&B*72F37G<((D$9*A3!5AC<&7.>-
@r6153
GGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGA
+
@HF2DBA3)9$"@97:D(F/'+6'C(0<;#=.E:$!@-F/-B1+!2G?-$
@r6154
GATGGAGTCTGTCCNGGCGGTCTGGGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTGTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCC
+
8C151&&0)>'5>7F'(6=00:3",&36/>3A<C/FGE<!@%#-E;91BCBH/6,*;'3'G3'@504"=7+#F(#G$@1+H0G1/H7B:64B=C82;B>/3!>B8<*=C3G-/.#6!>A=5#@;)-#,/'7).1$75<E7@(:(@,-4C$2B:E81D
@r6155
AATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGATTC
+
.GE;A,7FF5&";>B*++38F?1D(8>-'*>2$'60<91/9G#GC.$0G*C&261;0?C!?'>F143A(124'$1H/C"!9%
@r6156
CTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCG
+
487'FF?+570,G(&=6BHD>AB<15DC<4;213+H)@5#
@r6157
AGAGTTACCAGTAATTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTT
+
$'"*)&$%&**(&)&+)&##**($**&(&&""%%$(())(##!+'($'"+!')*&*'*&&''("%"#%!$*%$%**#+*"+%"!%$!)!+)+*+"")*$)*+'+%%$'!(#('$$&"&+++'(%%
@r6158
TTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGNGCTGAAGCCANCGGGGCACTGGCCACACAG
+
25?7/6'%42B$=8>(F7D;6/:CGB",:2!%+F56B!&CB95+E&H)+%C7'=5%41)F-7:''$
@r6159
CGNNTGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCAC
+
)&"#+)&*+($$#$%*#&'&!!*)**'!$*%+#)&+))%($+*!"+$!'!&)#)*&!#"&
@r6160
GTCTGNCNNCTCTGAAAGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGAT
+
*$*'(%'#!()**"*'+("&'('&%%+"&)+''%('%$+)"(%((&)&$+'"+*!#*%*#(%)&!**+!$$&$$")'!"&$'&$")"&&#*!++"%!##*)!"#!
@r6161
TGGNCNGANTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCT
+
(&%$%$&*+!!)+&#"&*(&!#)&#(&)*%)%#(+)%$$#((%%)%*("&+$""#*"
@r6162
TNCGGCGAAATTCCATTTTGCAACCGGAGNATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATT
+
)%25?=&!;,B60B#G6A8>E+2*-!C49(5>;!1BC>1)@3&2.9*>$/B'=E>'&C!;,-8"F(H:!6
@r6163
NGCAGATAGGTCCGGCTGCTCTGAAGGCNGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGAC
+
'$H207**(="@8+#8-82?"0#0G*3HD*9A$"C-+*)H%)4'64'A@.?F;+19.#&*-;:B,:1.)&):!
@r6164
NTGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTG
+
"D2#61:3=E1)-*5B:9'?3%,!1(<>+D;F/7:).0&(*55$4'&(!,)#;:5;<H
@r6165
CCCTGCATTTCTGCCNGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCTAGAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATT
+
718,G#%!;6G+0#2=<H-BF-)0*B6#"0>$<'+%;H&A4($002>%>)41F.(:=%2%=4C0"4)"=7/5'B8-G0:.77"9"A*%CD4G+E$E7%D1!&85A3A>:5?*%0"%C7F"=+4$&&68/1='&HF!F/B8"C"14$8H>!5<'');$*%>A'>($7=:"4-&%GC%".!4>G5.97"$9F0&2.F:*";-<4)$#"=$:96"!!!4%G7?#'C6B9B8=9324CH*2%(/
@r6166
GANNCNACCNGNAGNATNNCNGCGGCCTNNNNNGNAATGCNCATNANACNANATTTNATAANNNNGGNNNNTNNNNCNNNANN
+
!$"$#!"#$!!!"!"$$$$$"!""""$""!!!!!!##!#"!#"$!#!$##$$$!#""#$"""!!#!$#!!!"!$!!$"""""#
@r6167
NTANAGTGTNTTGNNAGGNATGNGGNTTNNCNNNNNNNNNAGGTTANGNNCNNNAANNNANTGNCNNGGGNNNNTNNNNCTNNNANTNNNATNGANNNGANNNGNCNGGNACNCNNNNNGGNCGAGNNGNNCGNGGNNANCCAGTNNNAACNGNNNATNGNANNNNANNNANGANNNGTANCNAANTCCNNNN
+
"!!"$##"!##"$!"#$$$#!$!"$"##!"$!!"!"!""!"$$"!$!!""$!"#$#$###"#$!$!#!#!""##!"#"$!$"!!"!!!#!$"!#$"#$$#!!!"$"!"!##$$$#!!"""!#!#$##$"#$""!"##$!$"!!$"""#"#$""$!""#!$""#!""$#$"$#$$#!!""#"!"$$"$"#!$$"
@r6168
CGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGAT
+
>-20;55>F#0(DF<%/94C%?$E'$#D36"'19*<2+>9*8-H6E&,H$5D$/#$G1*$$5;C.#+((=E$*9002C:9(($+,%?A),C5)&$1,2
@r6169
NCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCT
+
#8#%2.8$;1A1-!8G2GB8E7'=4AF"B*8DD;9$F8!("7FF
@r6170
TTAATGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTT
+
))6;86*#'H$B="H==-0=)DAC&9711.=(4D-)6C72)4*#*2B);!-*<3AA%A
@r6171
GCCACCGNCATNAAGCAGCCAGTNATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCNTGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAA
+
8!)@87@*:6='(05.>&27#51EC3;/<:.2G6*,"2319DB8,1=+00+!GA(/,-(=-3(8@7.9!!&B2-9"D;55#5<CG$.37G49;G&'47/?6>G-5>%,9:.
@r6172
TTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGANGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTACATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGNCAAACTGAGCCATTGNTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCA
+
EB&0?.#57@7=%&293$$*21@+"D>*5'*H?E9&/=(=D/';>@F+;!,#?*7$26E!:@"F'6"4EA)651*F!!#G81@D=4GH/'B<B,4D)4/;F3@FEC>C9!('A&1/EB)6@!G%AF-?3C"DH;B!!F@3*@9>:'@0B1#(FC*2<CC+4=#!2/1?#&'5;.>+@-#5:B9D<8E%'+1<"6=2/*%46$6$81>H/B3>9,7%G-%E?.56=9C25C9C)06;*.7
@r6173
GTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCNGTGGAAAGCCCTGCCAGCGCCGT
+
82*@B/?G,F@2#3+,$!>E8GHB7(4@,FEBC@*1$0GB<3564+9F7$3"AE">HF(:0()/G$3&-7"0G1.F=H94E$-
@r6174
TAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCNTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTA
+
G1?(+:1@68$;>G8@#447@/C1G<4!#78::)A1=H1"31>7>+%AA,-H6E=>C4:*:/(2D&7-&"7/309/7/34<1#9"46(9E)=>6-,.,=8'C$)6"4?#G%;*DF0"B136*01'>=06)';%9*C(5&D/*C(=2?!H6<8AE8#*>5:6)B987A-=64@#-"95.EC@G'
@r6175
AGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCGCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTG
+
F#*<E(D8E/'B<,/!)(F#+;,<!DF;49?F*;&#(G'=7?$E0$)3)''9>D,"D2DE#A0ECDH;7+@,/E&=648>0;'/A5H(5:7,AH@GDB>3)@(7%%+A?=@>';A!*EC,9
@r6176
GCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCNATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGA
+
,:;:H"**7+ABH=(4",+2(:D!'@>6D0:;3F.#?*')EG-6#"$$8F%-18'HF0?@8E:2#3A0:E:">9:A@6A:!0)/$A=3,6-&=)4&>22H(H'2B#)8.=7@=;@(.460<>B4)!,A.9"614B<41)(#):E+C=F,
@r6177
CGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGC
+
A89@):"#=D$$25?)!==+$&:/?C=!%A*D@@<"F,,A
@r6178
GGNATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAGGAACTTCCTGCTACGGACAACACGATGGTGNTNGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAG
+
()('+&#(+$+)&&&)+%%$"!%!*)!(**&#!*+%)%&)$!##!%&&*&#'%$#+&$'$(%)%(&"*%+*#!!(++#&'!!')+#$"!*"!*(+++*!)!&*#!*)*&+()%'$&)!!#&'''*%+$&**&')"%(')&$#*)!%#(!)")#'!
@r6179
ATACATAATGAATGATAATAATAATATTAATAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCA
+
<F*?0:@#5.-76@8/B,(:);,.37=%+E&53F(&H)*#<%#@<!8:*8>=/=/5'/#E-(4%!%;?8&'(8@:G8"7=>7
@r6180
NGCTTAACAGTGCGTGACCANGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTNGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCANTC
+
$+)+#*""%$&)$!($++'%%)!(*&*&!$!')""%)!&&'(&'&)''"$#!)"(&%*'%%&)$$!$#+$*!%#"(*%)")+++*#*+*"%!&$#*%(+)"&%*#')%%%*'))")('+
@r6181
TCAGNACGNCGGGGTACNGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCAATTCACGCCACGCG
+
'&"('$')!#&(+#%)#*%+()$%(%$'&"+"*''!$(#&!$&(+&#&)&$+$'(&')$*%$"('%%&&!"%"(*&'*#+&*'!#&!+(+*$'"&
@r6182
NTNTCGGGGGCATTTGACTGCGCTGACATCANCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAG
+
!)(&(*(+&"('*$*")%*!+*%"*%"""'+*)!"!+$!%"*$)%"$#'$*!&!%#"(+"%!)%)'**)'%*()#)&%%(%*$+)'+&'&)&%')"&"&&#(&$$#'!!+'**%%)*!((&#"!"%"%+('"&(#+%'((&$$*)++!#(%
@r6183
CAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACGGCAAGCGGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATC
+
(*#<,=F+,045-,$CG>HE84<,!.'3107:4-$-<>.!$39?<"5C74)?GB#H<!=A'=CH6,4*,=4E2;#18B-"58!;6CG7(7DEF3D2574@H2E"F(,%3D%E&$6")$H==@8$*=&GD0;&.474HH5F3:@.>+.8!AAAB74-+,
@r6184
GNCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCA
+
79'D/EGF389!A!1&)@).91'F;B'DB><!"55"2,+$+4CF.D,6H;6-.EE.@-:;+348">A&%
@r6185
CTGNCGACACTCCTTNAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCNTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGNCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCA
+
5$@,C--8:12BDG-A2H*E;!,"&A<A5@>:..6-'@"E8*1*D=2&#!=,@>23>H2;/247C;&)>7@*G-AE$/F<2/FG;#BD"EB5E,%%8$>>#;+9#)F)E%%1A8?3!&.-;@G,A.3@-7(+*?%4FC93H+DB0>*D=4@1%&.'=$F>58*5#D..4-5"E)4,,B
@r6186
TTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTANTATATCGCCAA
+
*:<3&>E49:%@03.A>6#6!?;GGH1B48H#G4H?:'?->F+6HGF+8FC6*2$%@?,D&/?E2G*:A?06CCEG,FG6(BE
@r6187
CTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATNCCGATGG
+
,>%H.#0:2H:47'H'56'!3-%/9?(8/)G2%<'CB?)<"E>4>
@r6188
CGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTNCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGNTCATGAATATCT
+
'#47+,#CAC6-H+!<0$F4DB;:6H17&;HD>:'FE$=F:,:$54F,B,+E%8B)5G58?8.::%!)7"H;'5%</+>2'?+3.5%)#%<8>)44)C!.'9EBG&#8BAD2&8=9;F8G4AE6&$#959$7'$A,>.H7H01H8?<#+'-#EB!B?FA<+2?&?<3
@r6189
GACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCNCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGTNACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCG
+
&8#(5+@+.)$&"?*)G";81*9.80(FBC6G4&FA;G$C<!("<#D;<HH;<!*.<);(E>'";H&H,;G@G-@@0"-8"EC!2*':/DH+,%,%G(F""<+<'&%&F).G1GGB0<E9=9H>%
@r6190
NGATTNCTGAGGCGNAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGNGCATA
+
!#&*&"#!*%()%%&+"!#$'"+)%*&$(!&)"()!($')""%(%%!&"(&&(%)&)
@r6191
GGCTNCACAGAAAGCGGGGATTNCCGTCGGGCAGTATAAAGCCGCCATGCGNATGCTGCCTGCACAGTTCAC
+
D%H:'E#0F+"+0-FFBE$#/B.F03CC6F!=?6<23E==#%<2G3<##>=%;4H;7?!(77)#F=5FF+37
@r6192
AAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGACATCAAACGCGCACTACTGGCTGGTTACNAACCTGTATCAGAACATGCGGGCCAATG
+
EH>@F1427.5,C(+#EE!')7905?;'9<8.@'CDH:9BABD3FEA"6<,CE;<AD3%70&DF4E!9'>;51"0B=24-!2565FH35%@6-(F<G
@r6193
ATTGCCGTNGTGCCGCGACGCCGGGGGCACGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGGTGTGGGGGANAGTTGTCGAGAAAAAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGC
+
%))*)%)*!#+("!*)&'&((#%&%+$""$!(&*(!!*++&"&*&+$(#&)"+)+(#"$#))+*)$+)'#$$$%*#$*!)&(!&'+&('$%&)()+"*"'!)&"$"'"!'!$'""+!"&$+!"!()%!'!''**'!%""$($)'*'**!&'
@r6194
NAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTAC
+
/D0BB-%CFB#C:*9!<)&C('F/22*BCD-/>";2B))G<4&29?:&;0."33%#*=8:H/BG#G*:"%?2*,!<"1,70,1>"B)''D!/9BHE>@A>HC7:,*>D$07$9.$4
@r6195
ATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCA
+
<=B5!C+$B#"D'?=:@('GG$/=4%=GF=/-14C;-%6=8$D.:@1(DE.;AE)"A"8FC,G*"6!1&C"28?7C'H-:*H<"54;/5B@0C?&82D(CH*HB+H'68#(+</F/C%-"A>DA-?:7'+)E9:3%?2>#'".8B"1G1&A):,*!&0A55G078AF$EH29;GBE*A96"&+27)7.812,FBG)8B@!+B2)"9F-?42$)(E+*>6
@r6196
NNCNTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTTCTGGCCCCGTGGCATT
+
!*'!"'+%*$+(('%)+&*''#(!%!)$$'&%$+&))*')(*$(&!'!#&+&'&)&#!!$+#!+*
@r6197
TCTCCTCAGCCGGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTAC
+
6%3@:G.<A-#(E6%!5-'+1E3.1/D9&F+,!6!(&!<)F"C2D6D#4D$:C*08.4F8#G9+*)C%?>.%8F#)3%'<*@4-;<=1D&8*3/5ED(@4*-#H8>
@r6198
TNTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTG
+
5D20>E>C+#(;0-<%('&4;#?E8GA(:8;#%@07?,D7H7)82+?6CE94
@r6199
NAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCCGCCTCCACCGCGGCCACCAAA
+
!-.6D?7<?(/$C4'+D'H'*?3@3;%48E+?1$2;G#);,+G00AF9"F?%D=.?1%$;!.>"B0B2'0+:*B%G(&"<($F/<&64/<,#<1A-D7*=!G><,(
@r6200
ANATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAA
+
)!C><+G<H-<B+3%":8&7!$?F212574?&+%/3$;/%?3!F3,H$4HH.8/G))3H,33#HE*DF4!A(%8-%2AG4&?>-E<+,F6:E!B,6G4@;?;C3#=#<.9,B;1<&HA>2",C@$D$#.@?&:,@,;?&DD'&"!#@%?50'$136+%-@"D+E0'980=2D&6*?3%&'CF
@r6201
AGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTCCCTCCTTTGTACTGTCCACGCCGACNG
+
9+@84"1:C;#!:,>>/%6G.>FH@.B'+7H5).&=-*$*4A<&@8)B"D0&H+#&&*@(*C"4<"?2*4D83E.>,*803($>$.#
@r6202
GCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCA
+
G!GD."%HF,%,?BD*#3')@.."HB1.#*""@??7%;A=2A)4G+#71D/
@r6203
TTAAATCNATTGGATGGAATTGTTTATCATAAAAAATTANT
+
"2%47&>%FB>!HB7)H>B$H$BFF?.=+%@D.>4A+>"A@
@r6204
AGCAATTAATNTGCATCGATTATCAGCTATTCNGCGCCAGA
+
;;8%70<;-:9"@?+>B40&1F'F+=.D19')1>.,F:);/
@r6205
NCGAAAGAGNAGCAAACTCACCATTACCGGATACAACCGGAATG
+
"%*####%$!)"+(!)"(+!"%%&&"##*(*+"#!'!%()#**!
@r6206
GTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATC
+
&/:&$=$BE440@.<.;@5H>+(&*CF9%5(+(F4,:B=F$=(+3?=#=FE"-FA198A(B>A
@r6207
ATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATC
+
9!!@A=;;<;%''E.5:&)E??(?E@3G@!-%<104A2%!,,&=7D$<@84F<1-6>2,C)7!81E3
@r6208
AACGGANANCCCTTNNCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATCAGAGCCACGACGGGNATCCAGCTTCTC
+
'##%#''&!'#*()!++('#(%%%+'#(("#""+$'$")"&!%&#!+&%*"#'+$#&!(")+'%*"*&+"*&"&&(%'
@r6209
CTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGC
+
;$()(,@-)9$8E<42120//:8)4.,&!"9A1@5-1F?,D?D2@.2"AG-E:"9,*;7G?(:=D7%=7*=>F$6F:"$3=0-H49**57!5
@r6210
NAGAAACACTGGCCCCGAAGGGCCATGATTNCGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGC
+
!7#:06'5D/740:?9B&>29F-)A%HBA/&CHH'%--99'3?BD3=-+@+A80G"4<%FH$,,C:4-F!4-9C::3/BF'G.G7
@r6211
NGAGGCACTCACCGCGCTCAGTNCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGTCTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTNGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATNCGGCTGATACTGTCGCCCCTGCC
+
!,)-C46*)-1*3=H;&,8C-77$BD&*#E'E-E?;AC95+4>%8>8?3'!(.C%&7#3'D<*/4@FF#.,6.9#=E.>H.,7@BFE*E7B(&1?'8'9B>F0=&F6-)68F03HBD5,$(D/;D31!?12CE,.14@=CEHD5A-C#*!1%/EDAC*1*=<4H(6!7*3=<;$D9#E1,F3-@31BE%@#(#:"#14G)#+$.0%=$C3D*<@=8"F'@>,)(DH>2=&$<A5@37')*='.;.@0/2":1?E4+/-,,A-=?GC!HG$16:7+4.6'47;#0G0(3C1"'2;B1
@r6212
ACGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCNTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCNGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGC
+
!>0D-0<$(G,+HD0/'F&>-;+@30-(GA28"AG8B79>.'@'-4.%"3(67@0.3:(<1/H?&H!.5?9#<H2H;4-.!DG3602*69?C:!&;5:106'?*-6'FB1H<F/68>/2(0A=C+&$,,=5!6-0$:B65"5$$&!!1H6<C46..D*H"04H5(57(:32*F#G(!**<?/F8!
@r6213
ANTCCCGGGAGNTANACGGGTATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCNTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAANCTNAGCAAGCAGGGTGTGGAAGTAGGACATTTTCA
+
'#1-G.(9A3H+)*A0/*%@>97*C6.=<E&,$4GB;G34?/).9ED'#5:3B?G<&)@A!*1(4&(B0@2'=D9#"A++;&$,%'".39H;@"6%*7&(C2-H;EBF5C98D'""9<&&3<.5?#;1HH2%!<=5F$B%37E@#*F",C%0AG/-,H,.*?4?37C".;17F.A(8>8=)=84H!4$H"&;H;!9&C.G+,///:G5=99BE232,506<3%8$$%E=2%%'?0++:?;;50<,!;:5H5&%@D;!9
@r6214
TTTTGATGTATTGCTAGTNTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCG
+
#)+%)($$)%&(&%%+*'%*)!#*"*'!'*%%"$*#"!+%#"*'$"(&$)#%$"')")#$#%#)!#&+'*($+$%+&'%(*#$#)#
@r6215
TAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGA
+
3;>"ABD<?#4%/E!@2.3+G<>F/+*.3@D'G.&0<?-!"E>@7/5<B7;GC=$D%8=#)&.:.G'*6;.*39,16H>E5F18B<)''5G2&?-$*;??>>)CG5"7"4+
@r6216
CCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCNCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTC
+
90H9);#E(9+:<2-2*1C&E..#AB8<"2'1@D6?<'39F*B3D'C&"84/3:A158$-/9"=8E(8+#H3?$0F=.'4#="FB3)F8:,479.4B9%C.F8=4?1B#C@:64(+-8;:%@8&.=!
@r6217
CTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACC
+
01-.!9.66EG.B*H6;6;,'/H>'#,=!9C!+44EED,6#1
@r6218
ACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCNTCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTC
+
7<(2@+2,D7C2A*D@A88#-33*?/**2<49H4>)?H"%*H".#,/8><$=!/%+D,-4:D)/+//.""'9%?CD;#(&C<G3%A&$.3
@r6219
AATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTCNTTACCTGCCC
+
-:&!-E:*$0'$@*@99/91907D0@3G=7#8#/A'7/9<-0D$5E:G@9$@0-&D*6#6DHB'63!27+=*/,?E*@3*+).#8+(@.5;?H(76%>F84B"*7;#A$A!6-<51%3=G)0$)0=A;+3+26"1%EC@C1<="@08=F,G'BA<//)%76=;B&)>0-8&D+4?"8-
@r6220
ANTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCA
+
&$+$+(!&!'+"'*&$+$%')"#$!"+!*()+*$#$#*%(()))%+(+"'#%$%$&*+)+$&"*(*+'*+)'%#"%(&%$"
@r6221
GGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCANCGCCCTTCCTGGTATGCGG
+
D<78FE(7G13>$EHB/<7#-1H2EFA'*H%"=+:B@=F'C/A>7669!@-:"9&F(4-+3.F:.F5F?EED>3B?9'
@r6222
TCAAGCGCAACATGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCCGGNTT
+
D=?(8)=,=?>=!(!0*+HA(#D.!+')"07!(?D+83(;!-9)53B'B#HF8-$'>1:8;&),")%+(!;E/6#?+-)?(
@r6223
CAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGT
+
..2'5-F3%,6F#(#82B4DEF&95"0"-3+)6&7"=9,#B<;%0;>,(-%E4E;5E/,!/-)C.9E,FA(*=9(!F
@r6224
CGATTTGAAGTAATATTTTAACCGCGAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCAT
+
%$8<:<<G!*+'EB$@2DCA<)4."5?EF%:?8G85#=2;#0++"&F+?B7A8(3AD+2?B&E02%1;E;F,13H'?1<-2?"6#7.'8039/<=C1,"$1.0"47:-8:-%&,+,"1>#4--!:8/<?2
@r6225
NAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGGCATCACATCAGTACCGGAAAGA
+
$+*#""!&(&!&&%"#*+)"$)$"&(&*&*("($)'&*'#(##(#&*%"&#$#$""'#)#&(+&)'*)'*%&&"+!#$$&#'!*''$'%#'*')$*!'*(+*&)$+"!&"'*')'(!+)&"##"!*#
@r6226
GCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGTGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCGTCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACANCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTG
+
$%*+""'((&#((')""&'*!$'!"#')*)&"+(*#'+)&+()!$!#$*+"*$+*+'%*%)*#)*'#&+"$&!+"!"*%#+$)''$%%!++%&(%$!!#)($('"%#(#''"*)*)+%+#()"#'#'!!'!$'%*(&#(%#*)*!"+""+#!$*%%(*$)#*+!'&)!$#(&%)++$#'!"+%(('#%)%+**+*#)#+(%+"'(*&)#+%)!
@r6227
NCGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGGCGGTGCAGCGGCGTTTTNCGGAACTGGAAAACCGTCATGTTGATTTCCTGAAAAGGGATATCATCAA
+
$!+*+(!!!)('*&+"*"%#$$+*$"+&#+'!&!+&$!%$'+'&")&"&*(#)&&'%'%+)&$))+*!!*(((%)!$$"'&+&'*!%"%"''+%&'#*'**&$#*
@r6228
ATGGGTCAGCNANGTANTTAGAGAANGGAACGANTTTGAANCATTNAGTNGAGNACNTN
+
%!"(('"%&&"#$(&!#'*"%!*)"!"%*&%&*#%(#()$#&!)(&$)#!)&%$%&&"(
@r6229
ATGACCGGGGAGGATACGTTTCACTATGTGAGCCTGCGTGGA
+
#"+)&*("&*)*#+*$!%$"%#$$&&'&)#("()$$%!'+*)
@r6230
NAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGG
+
#F-!98,',-*&=0*:%H7DCC5@9?!=#)"A1D005+?%@=604-)"=88.:=*02.&A$@>>A/3.<?8;*=9#&6*F-%C#-4/*#?;4?0/7GF#5B=H2&*2)2A<+)-=0>11F.
@r6231
TAGGCACTGATACATAACTCTTTTCCAATAATTGGNGAAGTCATTCAAATCTATAA
+
.,9@</%.,/;/HDG2D8(D&/5FA-$"D*2,?0G$,:3'HF/'*F'*A/C=+9B>
@r6232
TGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGAC
+
0.D8@"2>;E@!B03)42),A/.*!3.B1-2-A*"45-%:10A78<7,<3%(4GBCA42"DG.)<<C/)1*/92FD.*F("B;5-1!/$=720!!$97=
@r6233
GTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATANCAGGAAGGGCGCTGGGAAACACTNCCCTTTCAGCGGGCCATCATGAATGCGATNGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCC
+
)++"*)&("'+%*&*%)!'&+*#"!#"'''+$!&))#&())++"(%")+#+("()&(&&(')#!&!"#&%""%(%%"($&#+%%+)$"&%)&++#+)%)"")'((!(!%%($)(!*&")"'&('%'#%("&$+%&'+&)'!*+&%!!!"!$"#")!#+*(&**#$!%)##"'+('**&&%((#*%%(%'$)*+$+%'%()(&)"&#%%+(+'#'&&
@r6234
TTTCANCTGCGATCCGCGACAGCACGAAAGTACAGAANGCGGTTTNCACCACTTCAG
+
@7'A1'@EF!F'#5>->=956'5,15?1>4/"H#*:#'</$%='G$A!%FB9!',A9
@r6235
NACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCA
+
!H8G0CA%'H0(D<3/+(7'1<E;82:&H3&A"0*26>161%57".:%H5!6A'H/:=)F*!(:A9@A)(G<38&>/3;3*?>&)=<"-FE?E5>&F
@r6236
TCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTT
+
28.>:E0+!<4*0?;H<!D1'#4H<;$D</&D-H/4,'$7:7(7=1<(D($6:1"6,%)%2$"2(3.'"E:$A>D90?'G&:"E2*+,%!$.32&+)1B(@@>6:9'G,0-8""$/4:,7@'25>"<'*A3F0%)':+:?G7;,)#8:&C!
@r6237
ATGNCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTTACGGATACT
+
*)%++!&('&'("+')$!+&%((#"+)))!%'+!&&')#($+*)$!')+"(+(+%$%&%(+&()(#!('$"
@r6238
CNANGTCGCNTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCNGCTCAGGTCGCGGACCTTGTGACTGATGCAACTGATTCAGCACGCNCCGCCAGCACGTC
+
&'#%**%"$$+&++$"!!"+)$+##!**$'*"&!)())'#&'*+"*+$$**%$)('(!)')!*)"&$&&*##'%!*)!)+&)$%'&*+)$&()#))(*+*"$(+')(('"#&")&+%"''*!'($+**)*)$''%(+*"##(*)"#"&*)&&+**)*+&$&#*#'!&
@r6239
CCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGAGNT
+
?+"G>F'C;*E+##&#2>1.9#.3".#=<B49&>;,6+3=D<G8-BF
@r6240
CCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTNTCATTAATCTGCANACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTG
+
7>+G;/G&.-+BC45<)D-(&%2FAA"*/2=190)#3A>/#2(3)$9)4EA+(0"6B27>0H6=5#:%0*/6#H4!!&6%2BC21,6BH0=;+$D>(68)7>1==2$%(:""'>%',(0<<21*'11F8'!+#B+>AE6B"
@r6241
TCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCC
+
*7*5E))/=$;"(<;&%*D1=3"B92%G,::+")&@#4=;
@r6242
GGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAA
+
%'9F,/*8)=!;&*B!5F%>*B16C5&+"67:+H<F;90F1',(57<*+3#>F6)2;2G7'C8!/%//
@r6243
GGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCA
+
F*$F,+:'E+8.+!*"EC#8271?-#HG+!"*E@&E:?&9F1&(+/A(9)8>C69#')
@r6244
CACTCATTGTTGTGAGTGTGGCGATCCGATNGATGAACGAAGACGCCTGGTCGTTCAGGTTTGT
+
GB!D&*C<'GE2.01;5H<C"(BE:8"4:>2<4;E=7CE6(;F(7($E&5=)A908(;76=F?2
@r6245
CTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCANTATTATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATA
+
EFH"7&6+/$G!(A")F>BE%,(5#!7'8/+8#@D&.C,49+1:?9EEE1E502"..*"+14.1-"3E>D82<4%?4FFB?":<(1C:A;(5;(=E!*%5C*)$9
@r6246
GCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCCCGGTGAGACGTCGGAAGCGAAA
+
G9)F,3&?GC7F7>93('1F4=B62F8H;D./%<@31-@54.584BH9?=98$1D"FE?<-/@F<*C>D!>%GC2E-)FG632B%0?6,/;>0,3,4:3/78=GA@4>A2'-'
@r6247
TAGGCTGACCGGNNNANCNNCATANNCACCGGNGGCAGCCGCNCATCNGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACT
+
$*$)'#%'$$!'"#*()&!*!'%#"$$(+$"!%%("!"(+()(%%(!("+"*"#")$%(**("&&))'(#%""##$#'(!*!&+(#+$+)(&)+)!'&##!
@r6248
NATTGCGCTAACAGTAGGGAAACTGCNTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAGGCAACGAAGTC
+
$(@-7%)7GCC7!$-8>(+10$GG=(C#:F,;#:6CG1D'(-2&@*:8:-.6'>D=>HG)#7%8!#C=FF(.2*</:7%F?<E%)?7!2.3(,D."6D74*&C?-%2C,</(64<':"FAB/>(55<A,&F%!H1#
@r6249
GCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACAC
+
$3=8B:6@2'%#B*%+DH2-@."?B*?.,#126-@GE2,:$857-8%8"8D<>=9
@r6250
ACNAANAATAAAACACTGGCAGATNACGCCCNTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGA
+
(&!%'!*(#+#($&(&$"(!+(&$"*(%$'&+%")#*")%'!'(!$$)$$%+$+!$$)'&&&!(%&&#''"#*')"!)#"("(%$&&&$"%'$+)('()($$("'*)*
@r6251
AGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGC
+
?.$0H,6<1!41H%B&>$6-&!8D-HBH23(5C-;H))<A3:C%)F$)F(EA';62<GE=C4;=H2;:A<55
@r6252
NGTTCTGGNTTTGCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGGAGTTTGTTGCATGGNGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCANACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGAATCCGGATGCGGAG
+
&%"("+!#*()!&()!#('$))!')#%''$+)(&'*%#'&%%!&%"!$#++"'+)!&$!$'$%!++%*$'*%+'$%%*#)!&$&!$*$&$)*)""%!%!+))+"$+"$")$!#!&$&$)"!!(++++"+#(&((($#'*+(!$*!&*(*#+*%&%$"*#!+)$'%(++)#(+#!("&+)(#%)*"()$"!')+#%&"(%'$)$%%($!!'"))'))%&##"&#
@r6253
ATTGCCGCGTNCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTCATG
+
1-H8.<:%5!6,"''-G-G5"(%=2.(:=<#%-5&49!.3-D"3>)B$AD&?EHB$4&'H%7).51<'<*$.E<):1G&?
@r6254
GGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCG
+
B7+58!!@GE&G'#33G319GBE'HD=73B:7D:F@<*#+,)9$5-*$5%58-*6
@r6255
TTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCNGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGG
+
28>9226&:8<%=<?AC?=$C2&7E:4B%:?%61.60%1,3F#.,4%):8'#%HBBB$EE?;23CH'7!=%9B)<;38,0%9>-E$&66;A0.*%@D8:6!?)*2#AFA/4:+GG=(.5&,9,95#.1@.,A
@r6256
TATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCC
+
*(A"+&80F8=&CCD0D9DH%.4<,>+;*52B)/1.2&1>:-/C8-E-=?GD3$.A*0:1*,*C?8<%:C7;$=F&!>91+@258=%E&H0@!?2?,6
@r6257
GTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGC
+
F2<$'0)'#'1465G&1<0=A3@C62E2)))4E'+EEH+F
@r6258
TGCGGTAGTAAAGATTGNGCCTGTCTTTTAACCACATNAGGCTCGGTGGTTCTCGTGTACCCCTACNGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAA
+
.'5'.B.H#1)=!.=?C*E7?HE>0.AB55-@"B<0:@3=4>*D36)E3#<,86?9-C>--BF<'1%?4(44"-8HF(49(2(H2(!).H*%A12D>,".?2'&;$1&+F@9:2.,;(.$B>,?CG;.('*.7260'7B&!H,&7%?H"FACG0./A)-6
@r6259
AGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGC
+
9;=(.6#5/*3>9G8AF>)6HH!)CC=3*.;.+%#D,C6#.4?/:=1E&.5(#&:
@r6260
GTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAAGGTACCCGGTTTCACTTGAAAATAGCCCNCCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTC
+
269*G.@:5F02#+)!3+6A02(<?&5&&*=@':8H"E"/8E!3/#!/F+'3;-296%)%&<(F($C427A;B2?+#8(#2)@"36@$B5"4E$.8?9$)=EA*(22<$/+H8A5G:/5"6./+."EE&1)>27<)6A4A7%&0B2"4(F%<,/0AG.;*?.$.B'@F:@H5"9C!C48@?+GHD<%.!2?C+?C.".
@r6261
GTAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGNGCG
+
'"DD4CA!7F>87<@65A:7%9.-&-5G4%4+D;?=07B/3.?+(#1@E16=BGA3
@r6262
NCGAANGCTGCAGCGTCACAACAATCAGCCGCCACGTCTNCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCAC
+
-9*<);./DB5DA/G$E3-9*@/3C(H$G;-1:&?>&6;,93@:1E*",9,)@85:$/B("',DE5B$>C124+G17
@r6263
CTTTANCGTTTATAGTTGAAAAAATCTTTCGGTCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCACAAAGCGCATT
+
&"("$+)*(#+)+%%++#!%$+'$"'!*+%#$(&+'#%&'"$)()$!&*'#($!#*$"!#"'(+!#"!**$&!"($'&#$*&++!"!$(&%"!+'"'"!'')""(%!+&)
@r6264
ACCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACC
+
;*D<900!GG7&:(4@EA12"0<;&.)A%*+0FH<B3-$84+",A
@r6265
CACACATGTCGCGGTGGTTACGTCCGTCACGNTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTG
+
?HB/<,6&9+1/3.E'4;<-6-92<8"F"*(<7%*CB%8G54'"B03G8>!($F'08@'8&987E7*/D5)9=F":9;AC8$AH8?FB%C4EB
@r6266
GTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGT
+
2@&A9C@0-,+H3-@%6(7@702(#720E<?8%9.&3,-"0#
@r6267
TAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAA
+
E8>89,6E7D@'%-@9E:A,&0830G6D<16%F5G@:EA"7B72:&A#)4&3H!35C(H*F(F%;$0&EF6#?4+628A9&7D.5+(B*E,44
@r6268
ATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTG
+
)8+@+8E)/23&6#1@@2?H8#C8F*&B2A*H2'F5A;)(;/%/A*?F@FD;E60'.9C51@,6.9G0*$15).@/#7F&/%=*'&9*+0&$9961@>EF88%%#:8(923@/(*,75$D)3A#8!B")<E
@r6269
CGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCNACCTGCAGGCTGACACTGTACTGACCATACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCNTGTTCACNACCACCATGGTGCTGTTACGGCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTC
+
B?HHAC2B,:"(*?(/(-%%5".5C;.D4"7/-=#4F$,6?%F!!C$95G3?4<=G5!.838<43DB(>4H1F2@(;8'00C>.+;E18,8:4CE@/-$%5A-=7@(C'A@#16:$>F./G+/<+=D3.F:A:?CF.1D/7+5>2A&<5$5@,"A6=,+B8E"+,(!:C,EC"4<=)A*C%;)84;9B+;96,36>==#65*1<G'<:0=:)%+!76E@99%85-8B>8*>66H!3H>+7>61<1=>3@D+8/H.&,%%B%H#F2D'C%-
@r6270
AGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACGATCGATGGCCATACGACCGGAGCCT
+
)?.=2EFF)H9-?*&2;";86(C91=8?/-('7H-::D7=#(E?B/EA@C<.4#8,.@E>/F<2/<&=4;*%;.+(:AD(
@r6271
CTGCGATGGTTNGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGNATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAA
+
DFC&4@H/E!#8,D-"FD==43>:?;2D!+/&A(=-64A6"G:F&C#@A)((':E6?@!51'6$<6FG1!8-73$C5784@(<>15)H:.#&
@r6272
CACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCC
+
=B<81$>G<E<3*@A5=;:G#!&G5"+2%99H'3=.A;)C-*3D.0G8.#;/++012<D&?%>#EC1!.$5:4AC;5(A$?>-9">.G!>6@*9H>>9*3;==%*6()!DDC?F0C)?#2&&8>5%5E<=*E/=)>4(FA'3.!BF2;43.E$-0C%5*'G90EEBC
@r6273
GCCAACCTTTCAGGCATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTA
+
F127+2!*<1.8+(,4D4#2CF.G@1GFFF)2;,+./?"/27&C+C31)"<$-?,(C61F">>6;//4%!G1@A)H,/*?*%"(
@r6274
GGGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGC
+
?83'DHD.0D'D3D-3@99A&);B#@69H!/+097#D*C@$=/7.%0#1=*3#&+5H'=B>F,!>E'?%@&<@0!03
@r6275
CTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCATNTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGNT
+
3$7=GB;(&B6B%":(CF>E5A//C3DE,F20B,03)?-*)&+3A?"5CD<!7'D168"/B3=2/C=,3.5&%,<15+'G-F<.0&E86(A@8)G3%.11$!7(+;"!:9)<3:%1?,<B'$);<D$2,?)/>FA/(809#$($.+62)B@=0?0"17?<=7+E#(&!;@%A5<%BE<
@r6276
GCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGA
+
--.//CHFC)FGG4<?(@'!#'"B>!72C;-?CEE'%?"4*&+:<;((H"E"A6F%75'F@(=1@?%C@1H<F-H0;+%,'"D>?#G;'9#*#+/*';=%(&A6:H=?2
@r6277
AGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTG
+
1H,C"+$4E3?'.(8C:;)8ED&/+'!8FC4@8/EB!E0.$')#25
@r6278
CTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTNTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTT
+
()E<H658CA$!HD'4F("E$:D%?=+0$:?+1&D8F%+)"2C6F@)A49H0@.A''7D<8$%;*.*;+035$,.!#@6!F6>EF):1#%<<?;,)$:=7<@2+;4#33C<=@?6G(6.A.7$#
@r6279
GCCCGGNCNNCNNNGTGTTTTCAGGGTCATCAGAAACACCAAGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTAC
+
'!'!$('"'%"%(%%))*&$'%(+&+'*#&$)#"((&*(*)!)"+#+))#)"$&)#%""%)(+#%****$(#($%+''$'#$#)"%!%%#+('"#"$!
@r6280
AAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGNATTGCCCATTTATCGACATATTTCCCATCTTCCATTAC
+
7E3A$+)D=#)=+"88)CA+/+:8"+>&$);.E),0%0+/9@-F>%-F5.B0@-0+A0$A%=4)F4"9?!(H,:$4"BGD&&C"1!1'F0AD$F:%F/:CDH74?6D?$<9D
@r6281
TTCTGGCAGCGGGCTTCATATTCTTTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCNCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTAAGGCNAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAANCGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCNGGCAATCGNCATGTTAAAC
+
;:#8A!6&?2%'/>C)C<;"A1#:4B3463D@H,&6HAD,(')&D+$%8#()@H%!:00/@3@76A3-2<?@<0,*90$!A.:&!+&75D9.F.@F<8D*<;57A-A8@+-0=BC(()')"=!2E:0-$"(/C9&5B)9=)&)CDF(+G7%6GB50F48%;;G&B1$408!4*0E'#-:+5HH7;=;+(*$1C#"&'@465(F(0+C4*2!H=1.3G=8072%/&27CC=,2&H8>(H&11;E!D<)'#)19
@r6282
CTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACG
+
A?$H0>,D-5>.)($66%/BB'9<*77;:*;1E"H57<#F6*'<<1C;=7'F#<EDC&(>+CDG
@r6283
CGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCANCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAANGTTGAGCGGATACGGCGTGAACGTCTTCCCAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTA
+
?#0E7,D$$1+9F**F<EA5*&,4G21<<.<7C.8D&8G'71A;%718475095*E*>)-E3+=586=%+;D:&7.A/?!2##@?0E2,.8*;=B2!":/3*;!;:6F'F%$%3=B"/;".>7C&@D?.?(C-<8BF;4%4:,3,8$'E*=+=EC59*0!!3F*9CF$5=+C&9(985<10E;03/C83/!3=?%7'*3"DH%>&<&+;%&@-@94
@r6284
TNNNTCTCNNNTNCCNAANTCNNACCNGNNNNTGNNNCCNANGANNNCCAGNNANTTTTGTNTNNCGNCNNNNNTNATNANN
+
#!"$#""!"#"!"#$$"##$$!!""#"#""!!!"#$"!"#####!!$##$##!##!$!#$$!$!!#$!$###"""$$"$!"#
@r6285
GTCGAGGATTGAGCTGACGCCGGGCTATTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGCGGTACAGTTTTAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACNTTTATATCCGCAGT
+
/;=4"<+$;E:>>'2A;/*G644?9/)7DD*+1/-D9+5F(;A(:$:=3?:"9#F;#3E3!>/&F(+-(1F:@.H6,5#925$,+6"9?:!@#F?%%CE4)'%$23$'#++2:9%%/59/'=E3GA/FE2+G9C(5>40A(90$:0=F@*.9166'?+@*4?A=4=@4C/04/9.@;;#"-53;9"8,HA9B.:C>E#F2=(H08*=&#"#'A1B#
@r6286
ATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGATGAGGTAGTTTTT
+
43>1B1HG(D:@H$)'")582#F'0:G>"0)C&/?46+6;+9>$@+67?39/4BE%&,FF%
@r6287
GATNNTGGCATGNTCTCCGANGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTANGAAAGGTGCG
+
&&(!&*'(#&*)%#"*((%!+((+#%$+$+**$#&#))"'#'$%")"*'')(#"#+#&')")")$(%+!*)"#$)##!%)+!)+&%"+('""+%'%)'((
@r6288
AACATCGGGTTGAGNATCTTACTGTTTCTTTNCATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGTGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGNGTTATCAATGTTGTNCAGATCCGGTGTCTTGT
+
)EG5;:>%)B?),=H9=F'95*):E<FH@+++B3@GD!!$6F39!=E!>.9*CF/%.;(@:&/1F%*%(D:0@ABG2&;:B!!F0D(DH2D53/=#?H0'@4@%3<*;$A3&E=12!=E<A7=50H;E9B,1=,;0#3D)G%(44GD-=<"-0C$-6C1*%!
@r6289
GCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCT
+
G!!#(2-?#('=G:?2-32;:0@8/5>-'F8<86$"%&@H<20(;4@;E?-4:2?;62%*1"<&=73CC(3(@?!)@7/G?D1D;
@r6290
CCTNAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTG
+
1>'4A)(?%&#C.=27;2#'CG9E)*6C568H;F"8>DA35=0<+.!,@&2)"??(H1<#9-A
@r6291
NATATCATTTGTAACCCGTCACCTCAATTTTCAGACATTAGCCTGNGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAACGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCANGAGTAATTANGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTAC
+
&('#*!"&&%%!)&+&)*&&&&&%)*%$"(&'&$('#&#$%"%%(%%#!"$&!!""*$*!#%%'!#!)&&&&#'%$!&"#+($*$+('!%$+&#$+%*(+*+$)')##&+*($(!$!#!&''$"!*"&#'*$!!"#%'!*+#+&&*'%"+)+""$(*)$%*#+%#+")#+'#+'((&+'+!(%'+%+(!!'&(&""&!'!*%#%**%!#+!#&)$#''##&'+&(%))'$((*&)$(%$+$&!(*'#(&!)(+%$'!"'%(&(%!!#&$**%$!!#''")&%'(%!!'#*!**&
@r6292
CAACCATCTGTGCGNCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTNGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGCACCTCGAGTGGGGTCCANTTAT
+
,HA@)>B*6ABE&$)!H$B4<!,*848=!>40.=2!>3-DB2;1&34@--6D<!;%?C#.!5=>,F2AA%9#*@;&>.-!*C284F:F&1C,E*'>,$9%;#43"A2H%32#(!EB!F='?:'>F3*'"+>1/:FH34
@r6293
AGNAGTAGNNGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGANTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGNAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGNGTAC
+
%(")'$*'**#+"'!#'(&'&(*#()!*&(+(#!+!"&#)&%'(*$#$'$!$($##%)&&((%&*")*$(#'"&%&$#"%($!+*++###'(&#"*#)$*&$'#+"*!(##$#'+#&*&'&#!'+&*$*((*''"*)(#'"%$+$)(#+##%!'&$%("&+#'%!)*"#&!#"&('+(%)($'!&)#!+&#($%*((&$&)$"+##**&#*$+"(+!"'*(
@r6294
NAAGTTGNCATCTCTGGCTTGGACGGGGCGTACCGCCNGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAANACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGC
+
($$4+6=>67!2>+$B#8.6,(<"@C7E59%E#<HG!5,G>3$-=)C?CDB2C00'(C6%3%,.6;H$;&B48<;>-6E*.FA<?0B,@92(!&5>B975'"*F(2EB&%?7-=D=+,+D>#37.=?!!:-BG"B==%F6%*G;AA*@+(#A>::;++-!=@1>6:D<*=&;3(F+>&="'E4&FF1=5D#=9(1E(!E0A6-?3/-'B0D)$886+('77<GF-.B!)6%5BD4%3%C1F/EBC!./E4>
@r6295
GAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCCTACAAATA
+
5<2-,:)7#C5CH7G2!B'D;#AA&-?"2)E1692<&$,."/AG2FC3A$
@r6296
GANATCNATACTTATCGTGTATNCCCTTAGTTTTGTTGNGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCG
+
(&$!&!&(")$'*)$#*($+%&(%$#'!#()')*$"'))$%!$*%%**)*#+)%!""(!#)##"$$+#)(!'#$#+%$(#'&"+*+'(""%$)$"'"*"!#+"$&(#"#'
@r6297
CGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAGATAATTTCNTTACTCACNTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATNAAGCTCGACAGGTCAGTTATTTACCTAC
+
(.D3&(HD%8A3*$:6FF&7&)C3?(>'A.301F)9>+?+96C@<(8&#5=G/97&G;EC566B=@$@*"#?83+F3$%;>-9(?38+$:3<(A:.H;:<,;B(4E"869<<'4%=H?G&1)B%$C-&:H/)%'3:E8C6!C7&1@:+E
@r6298
AAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGCTGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACT
+
2.4'>'F9F73*;?6"2E%"'%#@7>?#4;HF6"#3*8%>)C+(08B#66H>+?/'/;072*4EF@D;B:)0%5@H.*-5#76%.)<C.)!-.?HBH%,46/#?9H5-7*H"1!)&D+8;FC)*"F'-.EHH"-;16A<94E%H!E1,&06<C8>F3,/H.#$"13G!FB"3.8$B#=)/('%=*#HH3"1&%#=)EB<@)B'7-#G;!?)B%@H(=8?/4@GB2!+),13F*2A(ECG/#4(#+D#8@'>39
@r6299
TAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGG
+
)1<GD'97'8B/5>!'.@B10#A&=5.A399=$3H7C998
@r6300
CGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCTGAGCAGGAGGTGATCAGCCGCTGGCGCA
+
</E$*65=G37ED83882&?0F<(H!:1;.&A:96<11'D)-07.G'1,=$;*7<F(-6(E,C%A!59*!&$(<":,9+-,*$7)9<&4E(C+7>D2E";"%)2G?D:229+(G>2+608(-79B<C41>:1:.%G.D:#G$@
@r6301
AATACCAGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATNTGCGTGACGGACATCGGGAAACGCCAAAG
+
E>!#<:22-D!48$(,50:,8'53>6;"0F5E;*,+6;.%'4H#!-1,B8B-F"56'?<0:<04%G$&B49B7'BA#"H;=F+:)6<$1(?@G:>/<?H74&/FC));/HE9#HF'?$7C1'6$G&:&-)E?GD541&:;+>'B5=1#D#4%=6
@r6302
CAGCGGATGCATATCCGGATCGCTNAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGT
+
;G%F:0E8;@!"75)D!<G9(E'F.A>)9.9%?7H/B;#'6%C0&0$$F'G3D0;F06-,;E$7#B8=/A.:)A&CC:0/'%1B.77#+"E45*>*618
@r6303
CACGGAACAGCGGCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGNCCGGCTGGAGTGAGTGGGAAGAGAGGGCCACGGACAGTATGTCGCAGGTAAAAAGTGCA
+
?)9",B*9*;B6A0GDH0.0&C;!%B$;-;.:;1/F0(=&BH-7*,*5-(D36D>>'C"23F:<=!5C$'!,E5**3)>1D'E'?H,$2#"0H!F$G,F*+:=A+*@.$2"EF#+/234#'"&!"H$3$?38D@'&*#B0C);?5*"F+*19):((#:B&H5"5A15;063%-FD;%&&CC?F(-#?
@r6304
TTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGA
+
D"=G7D<E-!H=!(1:C7)B?%B(4%!$82*2/46+7'!0E,$2D=6*:8$!(/."$E2)+.FCHH::"(&F$8-(B2)B.9G0@8.D6/"(<.9H>;@;6;6;'?:$D*3@=#.G%;C#%?>96002-1;CDA1E/&E@).=G>@3%%-.8&E*6B$>>1:8*+'=.E$4@H$8#')?6D
@r6305
GTCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAA
+
#.*%?+><!$'<9'3+/H,-/>2HF")!:.7.&H(#;24#C'B+GC3%E+0,@:93>':(/91BB/.#AFG!(2$+$F.,B?5?(A)%B32FCD5B//F90/C&@F:;7(!!2?F<HF<G$H;"G8)1,<-*1##<'2CA%*?,0FH=>F-ED&/&E0#BC("E?*.!D/
@r6306
TTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGAC
+
6C&.G*BB1<@3#==)<B1CHH&-<1!@C8<70B#"?4>-6=A1(7)";"-6#%@">D?911.,#/!/@(E;/%-13+B##&,C?+"@B:D@=4)%36=E(0@H+F5($A!,+)G137F)2H85",E(40%C8'+HC&E+GH,!,A0%'&
@r6307
GNNTTTNGTNANANCCCGTTTCNGCAAATCANCAGGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGNGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTC
+
'!#))'&'%($"(%*$(#'())%#")(%(!%((*!++*'#!"#)()"%$++!+'%!(+*$'(*!#$!"((!)")!*!**'+"&&''"%&+'"++)'&*"+##)(*#$!*#*$&("#&+!'&"+"$+("*(+&*+($$'&#!(+%(+'")*((!!(($!(+$#'+#*%
@r6308
NTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGACCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGNTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCNTTACCCCATTGATGTGGTGGAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCNGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTNA
+
#(*$'+#("$)+)($"))##"("&)+$*%("%+&$*'""(&&$!'$("()$*%!$)!)"#*))!$"+)$!%!)&"(&$#"%!''&))%'+&*"*()$$$%(*%'+!)#+(')(!&"++"%*#'%("+"+$"!#&*!$!##"#"%%"#+)$')*&)(&'#+#$#&%+"*##+'(#'$*")+$"+&('"(!(!%*)!#'#"&#*!)$#*)#%'"*)&(+)!!&%$)*)'*)&!!+&&#%%$&'%#$%*&)%)#++#(*!!%***$%*)"(!))%+'##""#"('+"!#++($"%(#*+(+!&)%')##"%)!+*++(!&$#(("$"#$!%##("%'!*"$#(*)(#"'%##(&!#%%!&)"$*$*%''')'%!*#!)$'$+!(%&+"&%%'$&"((!%$'("(&%#!#&!%"#!*()$$*+)")&&$&($%$$''+#*)%%(
@r6309
CAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCANTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTNAAAGAAGCGGGCGGAACGGTCAGATT
+
AB?++H5=,'6#.D5AA.#.G)#.H8B68:8+@/#227A*(*"47E-?65<?&"1%G2@0D/)$<'+)8$7*(G'&(2G'D1%3>)A1/2C1@@<56-C*04B:
@r6310
CTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCC
+
C0F!<A.!)5+>78(/,/@-D*9$0G+5@-E=E</<:*38#$886<FF*D7%3A,'H01>)E,=#@9-"$F:#=E'E=C6"'H'9GH9B*:/HHA2D*H5';>+G>1'(;9G&351F=3:!@2)=B>8+$.@=1(:9<B0%%0E7?A2E-4--1H-EB(3
@r6311
GCCGGAANNGCGAGNCCGNANTAGCTGCCAATGTGCCAATCGCGGGTGGTTTTCGTTCAGGACTAC
+
'''(('$%('#$$#"'"$'($$(&#++)(*"'"!!'%")#&#$"+!$"'*+%%*"$"'!"#$''!!
@r6312
TCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTCATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTNCATTCTGGC
+
DG2AH#!377<!3@17A34A5@.13#;/G1#;<D"78=1"C)<"&F9%35,/*F$+$16;89#3A*=.@1-!/1H%?H+;:,3F'&3G$4/:>4#9-D>,%->C,4&
@r6313
GTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACNAAACGCACCAGAAATAA
+
G9AF2>-600$3G"?E<AAD>.?))E#*#A2'3,<)H5&ED36E@<4#&@?>/:A?=,=&B?@,'-63&*F;5H%H1/A*21"H27+E&HF1=$1=(,A!=$,HBC76HG8!
@r6314
AAACTCCGCGATAAGTGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGCGTGACANCCAGCAAACCAAAACTCG
+
<D<83DH0"%8F)?.A>;4%AFGG0*G49<G7/48A$82,!!1"@;#B5/A<6/81C'8"D".*$51-$.5.(!!,7$9E?,)
@r6315
TATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGAGTCTTGCT
+
(&71-(=FA5E-!=E<A&25G@>:*&'71?..%&$4"$@">26E?E('AEF>A*B
@r6316
CCNGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGTACC
+
)%%&+!#)*)+'$*)*%%"+$+%))($#&!+#$'(&*!)&(&#%%("'$)+"#$)"&($*&'!&##)'+'+%$%
@r6317
CGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATNATTGGGGAAGTCATTCAAATCTATNATAGGTTTCAGATTTGCTTCAATAAATTCTG
+
HB.<C<:8?G*/>+<A=D4!(8-E"7=/H>6915.3?'829;91*%$,)9/:DHB!<(,$G+8:%%FHE;59@C30D+@."A":.8D,G!50&%*$4,C6E?125.$7H-!"BH,5*C.5G2F:%E5G<$HC=3H?(/;2)0$=9<.?%6,!).*
@r6318
AGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGAC
+
)B74&+/.3#B"(6-F?5*6$H"%5!"%">"(>87A!F%0;93;'83EE'1C;<>(?4&F)-'9
@r6319
GACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTC
+
<7AB6)*16',($E3E%5=F/A(#H6FE":F@+@+'<"+H4<D<89@;2'4*$G53$27"(5.0*1-HD;1B#-79D
@r6320
TCTATCAACAGGAGTNATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCA
+
?%=*("'>#7<=''<--0A(.4+B""4G#4&@D2/2%1#9*(*5,:->-&#G9'@C'@$#E+1F4CH*,(=?"!A&5!@4G#@!&C;1-$46.!8.7="5@C5=$%1#E0=4B9+G%>E.B5'HD."5%-/A&9:H:1/:F",&-!3&
@r6321
GGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTAGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTATTTAAGCCATGCACCGGACCTTCAATCGGCCCTTC
+
10-?9*5%B>)G.>;)'"%F2.6GA)..9'B"D5<F%2GC6,C=F)1C+.(58>#=*#;,#2-B*%1:*?'?+&77?'+#4,/".!0@BD.(2'$*3HD$F89*!"E@H9+1,4.A$%,*61-+'$2,G*4>(@%;0
@r6322
ACGTCTCACATTATATTTACTGTCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATNAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAAT
+
3-D'8&:*670&5.,%5+3,0G$C%F664'-"7HD8?)'7#7@1C1/>8-3%$"BA%!=?#%E&$23-)'>E"01B>;),?G5CH9.'$3DC+9,,:.B<=<6*:":9$";&H%#!8.C@5<649-75@F.(34*F#B96=.-*2)-;H;H4,".0$)(:F*CB1'8!%2@$'.=>@=9"FC*?5
@r6323
CGTTATCAGTTCCCTNCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACNAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGANTGCTACTTAGTCCGGCGAAGTCGAG
+
D?&.E/6?,(>?E<EAD1E6%!F$;GF(=H/2%24%G82:.'4"/@H0++<-E)<'!46+'>C"=4$H?8-HC'-%2A'9-75F6#"":80+$;62<&%*5$:!4>-HG'7$+"F<0)7HHCBA7*B#9=C:3H/+0B3G$=9?"G,$G?#,<9%06792?A'1*6)D&10-;#4G5CA*>8@B24*8=.-0@B
@r6324
GGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTA
+
;=,H#,%,C(H9"6)9)"5D,F@#=<DD:(&4"#F->-9<!<0;-,@&;#<079B/E$G;0"/+7,?*D02F/1<@:@:F?!3
@r6325
TCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATG
+
G130>F668;D8?:)7.A*'*#!H:*0C"//>!)54/%$$#?>89F+#03&)A4+/7.B&':6,/-6*9E-<&./85.?<&'A!F*2/02@'$26=(33H*$!$:-
@r6326
GAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCNATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCGGGTTGCACACCACGCAT
+
&11H6$C63#?7!53'&?3A.BF2#07@A-2B.)75<2FH1=2F*/$)7F2&A.6H-%6<>,AF=3A=CDFF%95!17=4G2(DG?EE6/,,EHGG>-46F-6#D/5G,*9@'$5/'>AB-&H,D>%%6#2+?E5=G?38,:+>-8E,E>?89"*1/"C$A)6'-$,'@
@r6327
AGCTGCACTGCTCAATGGGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAG
+
#<B(+(F:,$@$+0!?.(%9*&)+E5@'*&F25-?ABC83!>54C&5HG<0,;</!,HAAE,'8@=&=A01#=C)=62&)16#?6C6#
@r6328
GAAGTGAACGAAATCCGNCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATNT
+
7*+9%0C3C98@>:83++G9G9.F.0D3$EAA''.)8D1>D**+767,0:1##;#!+E6143>*$GC$&*&H<FHE1(<>*75<.'#/FE?/5!!;.*@0$A&/5?H9)<4'=A
@r6329
ATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAA
+
)+!"(%'')!'!&$&!!!&$$%%$%&+#%&$!#"(+*")")+#)()#)$')+")#!)(%#!)$'
@r6330
ACTACCCAAATATTTCGGTATTTGCTGCCATCAANTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTC
+
1E70??->)0?$4'+(=(DF=5B4"3F26#-+/3/;*<9:&@;65AD+B.:B=&5.&$*#;D/D0:CE&$0'CH-6#-4)$9H<6)E9#&
@r6331
GGTCACCTGGCAGGGGCGACAGNATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGNACCAGTACGCGCCCCACGCTGACGGTTTCTGACCTGTACGGTATGGTCACCGGGATGNCGGAAGATATGCAGAGTCTGGTCGGCG
+
"+#$%+)*&"+++%#$$+&#+))")+$&)*"($'*#)#+(*$!)))("$'&$+$'&"$"($('!%)'(!'%""'!&%*'""$$+(!(+$((%)#'+&"!"("&%()*+*'""'(*&"()#&"$+!"&#&()(#'$&%*$%$+(&+&)+"#((&#%*&)
@r6332
CGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAGAC
+
B721H(>F3B&3>"'=63#99!<E:EC#D38)0;/G-*0DCG"7C)=GG',0@'D+3E!"0?&BHD94C!A(F&?A;D*H-6,'H,(HE-?-E0>1*2+,9)H=-A#!#?#.>7.!1+(80HH;!(GD(?#>F856:6&;H:B%:8@9D@?:?+C15515"4H9
@r6333
GGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAANCCGATATGTCATTGGATGTTCACAACCTGTNTCCATGAAA
+
3%.1#(2H&F8)@H'A:%BD0@"D-,5B:2)264FH%4:"85F2:4D@)98H+"7<8+>#<)*+#)A-E0/G4*H*!#7!9+
@r6334
ATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCNGCCTGTAGTTCCCC
+
*34/H#,B*818@<;=B3#F&,;6=CC5.#!-2EA",1D'F1B+=1;(87,$&A#6><=03"2*D:$/
@r6335
AGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTG
+
*(',G?A,5&094ED!-G!!E+)8'?/-G'=<'#/)=53-H.C2B5;D'>5#>#@:8<*@DB8-E7018
@r6336
AACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCA
+
'84?3-%-@B+)2;7(FE=7?13&C#7HDC)F2HDA7%H8%5(-28'B$6*!!+;14**#>*+$,7A/2;:30''*)E48EHA4A,!H5#6"=#4;4F"C/$#$88<'8@C9A;E15'+
@r6337
TACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGNTTTCATCCAGTCTTTGACAAT
+
);D6!<#.'1"8;-?$1/C&?/1;&43)$'D5;B/-F,!)-4F,D%!:'G?=("334
@r6338
TCCCCAGCACCATCGTGTTGTCCGTAGCAGGANGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACAACGCTTTGCCCAG
+
")3"(0#9.@H:<646DD%335+88<1#FG/0@,80G-0/#%+!69BAH#%!:3?:A$&>D9!CHB=E+=#@118F0@D)78F=BC5/'=36E*7*E!3@2>;:94D6EB7#96?)<H1F.G=(0!
@r6339
CACCTTCATGGTGGTCAGTGCGTCCTGCTGAGGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGAT
+
H$:'5?"*D'77',*>;@E57<DA>9?7A"A)3(5<.?>G7%1$9F,;A*1#"!"A,@8573/C:9+1F:4/5$,="G+7"0??..:'-/98B@(1:4A2-0/&A0BG8-EC:&8)HH.=H9<#/AGD;7("8D-&3/9'0(0:@'>:G)G8+5D'CG7#1!='
@r6340
CCGTTGTCCTGCCGCTGACAGTACGCTTNCTTCCGCGAAACGTCAGCGGAA
+
!6D49(!1ADG(D4*EG&074/!7*@7,1?(2#;.E",FAE(<>9H@:3&D
@r6341
GGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTG
+
-%4/:F(D-2&ED#7"#AC)!=EB5%D#@/=D)!D;!4"8.H@=G!$+$*1+<(-+7(C7
@r6342
CAGGTTAGAAATCGTCAGCGTNGNGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAAC
+
?&=(.2A85<A9$/*A0A)5*<@2>''4!D2<>%CH3)9F+#7#9H-0/@@BG:(8C)E
@r6343
GGCGGCACACANTGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTG
+
!@7#"$=EG+&*E,+$8>5B.1DH<7=<::9H2"E((.>4"/0%$(:%+22)65G90>G<2(@E.@9(B1A)(877:+1":8+%''%/D(!;:=7?"+3*4)GD<-B/AAHF"A%*.#B>C5&"2,5&:")3>DA04:%723"C@*
@r6344
NNAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGNCTTATCCGTGGAAATC
+
'$+$$!)#(*%%)!('++*"$)%+#$)&'$'*($"%)(#"")(!($*%%*%#&"*$%
@r6345
ACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTAT
+
4#&4F0F1"!,"2,EAF-;/>;>==>3-$F',1A;4C2('D>?B!71;!/5?H;=
@r6346
TGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAANACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTG
+
G=*&A#G80D1!0)&=GD@?+//G#CB#5#4DB,@BF?1#"G4,9@.2CA$$'G+*7>/"/3G#4G!!C1;=70=+1)72@?<8%"$8@"<7@C:3?>-?3=-FH(-%:;;2-8$<>#+-=G'43.A1&##)=3<FGB>(C*:6B&-7!:$E8$8+>(&C@
@r6347
CATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGNTGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCT
+
@D;B7',2@>FC&0E!D=>.'',3$%(22FH/8/0/-7/<"09F#E(<E9-,())F/$:#,H6.)GE@;#A@<!+A/5,,.F$33&<,-'0&&!H;%$72C98$B>91G44E8-6>$1.%@3+
@r6348
TGAGAANTCNGCCTTTNCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGNACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGNAAACCACATCGTCGTTTGATTACGGGACGAAAACANCAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTNANAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTAGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGCTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGT
+
;F<2H*28=6@5G?/<4;&H&6*;1<!E6E6E/#B22;H..2'F+H3)=+1"E)8%&!)+E,%)&"%*9!,$%F+2'!>@):/21/>6*;,.G<+>5,#+25FA-F.'4)H-"5(>@D;H+<3>6FE&%;3)=+&,0+"EE/3?-HHDF33*3.;6@H/9+@;8CD*H1*&C%C12,"$?5@8,GF'=>>#-(->)4;)(1.7:F6#<7:3F;D.*208!!%72<@9:%D?E,2&19G?3><1;';#106$*D;45<>"92?&)?:5')-</2(&+9/.E@(?A?G5+"(/8G<<(50$E<@:8=2B:#8,+'E1>>C<B.30((!#4A)"3;5/3;.3H0H<>03<%@617"2!?GF&/'C$A5H%>>@&G*;G9>G%>>(E#,D@>7-A.(D="&(4-F*,HG(5"7FD0)?7F38-+H*'5GBF%/E>)F**:>+2!.A8&+'28(-98A;;(,>3G8%.6H*<<D$?@12*4:5;F"80:,GC.3&<82*C>=+4!1-)7G"<2-#,(A3&6'&E2'=?/37+'AF:!8C)9:%/+*EB+2A&"7.?%6':/C>-
@r6349
GAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCG
+
H)/#@&0*7,3F1-'/>(->)G/87DGE5,B!B;EF1@<4F:D<BG5;D!B-A1%'F@;C33CD@B/.(H73/@#8F>:<)(/:,CHE''B853"
@r6350
CGTTCCCATGTACCCGCGTATCGTNTCATCGGCGCGGGCAAT
+
><,"")+.F-+70C&G.;"A'F'2)0*E(,<!=$1(63E8)H
@r6351
GCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTC
+
FHG.$11)>5G<4!<+?AH!E+-)##GGGE5H"1C>0;1=+#1#@7F1?::A2(E-$
@r6352
TCNGCGTGNCTTATTTCACTTCCGTACCCAGCACCGTCNCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGT
+
;):#G)?47A>HE??@A!&G"+!HG@200F)/F2@9GG.$!8!6*:7%"H;79$D(.ED!H$6:--0"-H3A?
@r6353
GGTCGACAGAATCNATGCCGTCACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGG
+
%+"*4F1*#&H37',0':->($8;)1H7G:#!G5'7%'/C'+C&F;"HE!9?#H3)3D5,+%=12%&'A"->@!D"437<GD8+A:.<8;/9&'-82E7$
@r6354
NCATCNNCAGGCCGTGATGGAACAATACCAGGACTATCCGT
+
!((%()!&)%))"&+!+&&%#(%+$$#!#'(#+*%)()!$!
@r6355
TAGGTGCGCAGACCGCGTGCNTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTA
+
H*!==$6@E#)+:)HFC?4=F8'-0;;9HE()!,*>F*(94@8H74*H2!E"A9
@r6356
CGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCG
+
C8:/!@E?6"(F*!03-8@E98D0D3AF/6/8!-9+A66894@*.)5C3:)H(A2$BFD,"GE$H:=%2=C>,#$5!"*'85+6A!+E1,09H%H!!47,15AC%7,%AD=)?6$,!77E8=*H*09;/D
@r6357
GATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCNC
+
BA8'2-(8&A210.+:!5B%B)%C428E!7*5A:(%6H3+1+C#':BE5):,1)>=8?&&GE4$0#(>;&1$=,B2F6:G+)1@2!)
@r6358
CNGNTGTNGTNNTNNCNNNCNGNNGCCTNTNCACCNAGNGNNNGNCNNGTNACNCTNCCAANTNGNGNNATNNCACCNTCNGNAAGNGNATTCNNNCAACNNTCTTCANCGCCANATNCGNANATNGNNANNTCNNGNNTCGNNTNNNGAATTNNNNNNGANTGNGGTNNTNANANNCNNACTNTCCNATCATCGTNNATGNCACAANT
+
$!"$$##"$$!#$"!"#$!$"$$"$$#""$!"$$#!"$!$!""$""###$$$!"##$#$#$"#!$!"#$#!#!#$#$"#$"#!""$!"#$#"$!#!""##"$$"$#$"$"!####!!$"#"""#""!!"!"$!#!!#!$!$"#!"$!"!!"$!$"$!"$$##$!!!!!"""!!#$!!#$!$"$!!$"!##"$$$$#!$$$#"#"!#"!"
@r6359
TCTTTAAAANTGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCG
+
)%*+(*$$("%)!)!"**#&$%%%#&)*!!)#%&'*""#!"%(*+((%'&!"%&')#!)#(#$(%(#"*!&")*#$&*&*$$
@r6360
AGTNANGAGCGACATTNCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTAGTCTGTTATTTATGNCAAAAATAAAGGCC
+
%))")""+%")"*"&*%"#++!))+%+)$%#%+#&++("!!"'"%*'!+$$'(%*&)*)#(*#!*)%!#+!)$)*'%(+#(#)"*+"$'!)
@r6361
TTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCANCGTTTCAGCAGCTACAGTCAGAATTTATTGAAG
+
04#3):==B=0#/!C?3E),/B;6;-#?%G.>"HD$**D=6+?998+8)CFC'7:-B,F,'/=3,EA1C$")3.G&*HD<,A?7)"'3CH'&-B#?304#=@3&++<AG75.?(;)5,
@r6362
CGTTTTGNGAGANATTTCTCACTATCCCTTGCNGNAAGCATNTATTNNANNTNANCCATGCANGCNNATNGCGGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATNAATAGTCGTAGT
+
*!&)##("(#'$!$&)'*%(%"&")'%(*$"%*#!$)!*'&)(#("&&'!)&&**"))%*&)%!*""&&&&#$*+)*#%*"+(*%#)&+"&)%'!"'&%'**"*($&&"&(%&)!")#+%''*")&%$("%*'(
@r6363
TANAACTATGNACCAGGGGAATGTGATTAATNCCAGGCATT
+
#&!*$"#"%)%&+"!$%")%)+&(*#'*+*"!'(&%*'"+#
@r6364
TCTTTACATAAACATTGCTGATACCGTTTNGTTGAAACGACATACATTGCAAGGAGTTTATAAA
+
$:;:.*;<'338B!6-<C8=H?2!(!;336.(!H(HCB@.'-H4-'7?=F8288<@7&G64,$C
@r6365
CCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCNATGTT
+
47265+"&!:)!$.G!?FC>>1.F*$96:?D*2$&1GG2?7D!D?1#CC7=7
@r6366
TAGTAGTATTGAACTTAACGGGGCATCGTATTNTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAAT
+
HC-9:06E'(D3HD+0,C;3>)E4ED-8*C.,9,$&8"F99C$<7FA,D$=>5>;(!"2#(;5.E6>).$F!%+3!51B*"7C+D4>2D#507-4=-;?(9.C655(/A#<-!67"C0##GB#'!079'9
@r6367
TNNTTCNNNACNNNCNNNCTGNNTGNNGTCCTTAACNNNNNGNCGNGGNNGAGNNNTGNCN
+
!"#$$$#!##$##$#"!"$##!!$"$!!$$!!"#$!!!"!$#"##!"!"!#$""#"$$"$"
@r6368
CACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTCCTCGTGCANCGAG
+
55;FC!.)9(GD%@$7.'+&6GD7:EDF>94.->AF0E><9@/G:+(#32GB:@CG$?6#/*2G,?<3H7=4??($#&?+=?F63(!*#1>4G?"',?/8(6F.C2
@r6369
ATCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTC
+
#:H;23;+:#.0)A--1>#G+4+A2;!!"7FA2F(8D'):G%=30566CD?>
@r6370
AGCGCCACGGACATTATGTCGCAGNTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAG
+
048#/&=41(.9!88EF11?:7#+>C!1(@H;24-GC@-@@&">&C0@;G&5(2')+;*;,A>D"<)1A#=C-C41?,3<E5F5G&EE?4603=&68E.
@r6371
TGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTT
+
"<-%/5@=1'EFB%*$9186/*@'F$-A0GA=(=008#+$:!*/B!.90$/=@92GH&3#8/FCE#35:E&E"7/2>>2H43.46.5;+5,CH-F?1)/'5=D+.%G?)'4+@'58B&G?;:)BE@6!0-@>EG)22(=?>7%,B/<"F*4'#!@H=B2C=
@r6372
TTTCCGTTGACCAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCTGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCNTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCT
+
6B)%?/*13+'=%6+-'E5A)62%,-*.636%8>+DE-9>-CC#$*1A.CD06)ED9$BB>,7C2@0$9%$03*)CCCFF=@@<+&-B9EG,&74$>?*/3B3!,)A(F24#?A/*>7?"0&+$A+:-H()-D2$,(&D!98!(F,?13%$/CG-"@,9-;5?5D!H?%#<C<'"0*BDE9'7B=&5A(3-<0!?!8AH,4;!<-/)(D;@9BA15&271?(?A/CC&++&
@r6373
GNCTAGCCGANAAGAGCTTTCGTNCNNNCTCTNCGGATNAAANAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGCCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATNACC
+
(!#")!*#&#"'#(%%$$%#%%))&!$$%))')((**%%$!)"&+"(#$$*++!&*)"*''#&&$*&$#&('#($+$&%"&"$#+$&+*')'%%*+')*!)(""$+)%*()"(&*)*"&*)&()''+""$)'('"$'++!+)*)+(')""#&%+'++&##+
@r6374
ANTACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATG
+
*$C.B%/.0+*!/,7>42"0!%/$=8"G#D.G-75E-).;E9=F43<C!$A>$:
@r6375
AGCGGCNGGTCAGCACNGCCCGGACGACGGAAACCACACACCGCTTCACGCAACTGGCGCNGGGGAACTACAGGCTGACAGTCCGGGCGG
+
<$+>AA:GEF&!F=4;AC1(@D69*)E(!5/3$D4A+7.H'9G#=+"B=D$3.5:311(G'>A0!6,(D6+(2)@:@2D8)#6E8&30"%
@r6376
CGTCAACAGTGAGGAGGNTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAA
+
&&1,=?$!1&6?;A'HD!7"(2D53>,:A"6/76'9'(=-;FH.+.&>7<)H1BA9
@r6377
TGGACTGCGACCGGGCAGGGNCGGAAATCTGCCGGAGATACCAGCTTC
+
'EF9<""#6!C$49!!&9):E+E?@3F:*>4)%(!=A1%C3?"1.C@;
@r6378
CGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGAC
+
EE/+.)*9/'C0F'C,.>3//3=(!6(;,5%-<1*5.243
@r6379
ACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGNTNAGAAGGAGCAGGAA
+
';@3@(@0H#@8%'8+/0#B*C8+&4.0<=,@#'68D<D8A*A'"$AC>+
@r6380
CGGATNTTCNCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCNTATCCCCTTTCGTTTTCA
+
)')#)'#)'+')!('!#$"%'&+*(%(*+%&')*"('*+!&"!(*%&&%%*!#)&&%'"+)+$+'&)"'&#+&"+"&+)'"#+$!&*%%
@r6381
GCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGNGGAGCATCAGGCAGACCCCTCCTTATTGCNTTAATTTTGCTCATGNAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGG
+
>!>/;&71?<3GH(#79D'=9'H&;*G2CG81<"6(9;..@7<"6:/E7;!HE>93@6'1$%>6F3C*:0'>)1*E@-:3B#!.,--<*'D>?E.EDH:G*D#F:7&,5(.G=F8A9<E,+G-*(C??'!5F#AC<0B',&&56#>)15')!HH&5$)A0EE!CCC0*HB)7?=/D2G-<*F$60EC
@r6382
NGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGNCCTCGCTGACGTAATATACCAGCGCC
+
$+(4+<B/(H>?,H>63<<0;%0>$(@#)CG&*0-A+7&%F,)A4$><<#9CF8"D/.<;@E*G.H.*0*<3F!>/>36.AG?7",&82<3H1B81?=-H-$6G+
@r6383
TGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGNCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGC
+
;B+))&BG7C43@&33)*-6F.?15*=!(H,%.E<&3),*.4<%50#BA,G!/>)F1A:.?:>B0209H,,-,%G8D7C2,>>734"/0<H*66,H1?+./E8B.*
@r6384
NAACCAGGGNAATGTGATTAATGCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCC
+
)?53+&-BFA.H3D8"6"'#7#H<'.3+74:C2C*"?0#9%(<6&0B%F)(3@=%>#$*2$-$*;=6
@r6385
NAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCNGCA
+
)(+%+*(%&*%))**$$%++)!()#!)'*))+#)#!"*$+'*))"%#%(#(&%+#$'!&***$%+!!("'))(('+(+"$$%)&$''
@r6386
NNAGANAAAAAATTCAGTCAACTCCCTGAAATGTTTATTTCCTTAGGTGAAAGCAT
+
!!$*)$+"'*++#%+)&+$&$"((#$#%)+)"!%)%&)()+"'$%+!#()$"$&#"
@r6387
TGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATT
+
1#"=.&?)":6/",2%0F393H<E'$36+:?*A"1;5*##>;C*'8-*#50H$66+EGA0&'%1-"*0<%G
@r6388
TGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCNGAAGNGCTTCGCCAT
+
%+)$((""$'")()+%*&*$&&%**'&#&*)((*+&*)&$!&#(%!##$!
@r6389
TGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCNTCGTCCACCTCCGGAGAACAGGCCACCATCACGCATNTGTGTCTGAA
+
!:5A1008)==$@!>(:A'&1#>27/&;071'G'%'<''1(-+9,,*G@+=?61=!>/,#/H3H.7!5H+&?#&,843D1<,@7+0&.#83C0(4<5A)!G"<G2&/>2@/A$%H(#6+7A;56$1$(3-0*7:"C
@r6390
GCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTG
+
G"AA!E-(EG$D6$?0&"575/,-@62!:80/B<!>&+>?2!0#H9&8)4<7"8:3+1E+%;""26'(8A2D+&C%8@.+;!=(!*A"1!E6/&(3,5G3/FE.-4<##
@r6391
TTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCNGATTTGCTTCAATAAATTC
+
0<)EC44-<//E*$/.-6'5+G01=BA"8&:FG(10.=+5(F:;32,#)A>6-<F0(9$83<A3
@r6392
NGNTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCT
+
$,87/%4'7=7B+807%&>)%A7?>F7>/E,F3!(3+BF3=@.*B=C9=361AC3D,(:#%?=%*
@r6393
CCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCNCCTCAACTCCGATTTAATGAACGCA
+
%:&A8F)4ADE&$7%;0;%3"H"78;'1A8!538B8F"!=;H71.#.C/C#4E'H0/9-(6&3E*<=0<D
@r6394
CGNCACGTCCTCCTTTTCCTGCGGTAGTGGTAANACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAG
+
)"!+'"&&*!&%!%"&&'()#&&++&$)&#$)*&!(!()$('"(*$!(&$"&()'!"'#'(&')$%)##*%)!''!&$*
@r6395
NTNANATACGCTGTGTTCAGNAACACCGTCAGGAACACGGCTCACTTTTACCTTCNCGCCGTCGGTGACGGACTGAACCTACACGCTGACCGGATTGCCACTTNCGTCAACCNGGCTTANCAGCGCGGTACCGNAGGATGGCAGCGTGATTTCACGGTCGAGCGTCNGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCG
+
!)&!"+%$%"*&"$!!(+()*#"&!*#&*&!%*%))%%"#("%&)"#!")+)'*""%$++(&!"!##'#($$+!*"*%"))'(+&+#%'"(+')!*+)$%()&!)%("'&!$(($&#)!'"$$!++%%$"&!")(&+*&$!$"&(*$#+**(%#'#'+(((+#")#"!#$($"*'$'!$%'"+!!"'(#$'#()#&'&'$$(%**&*%)(!(#&(&$$()
@r6396
NNACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTAT
+
"#432C?A-H61H97,$(@E#9('FC+5%5./'$%$+@9?F?.0#G'$B@9#@
@r6397
CTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGCCCGTTGAAAACCTCAGCCGTATCAGCNAAACGGCGGTGCCTGGTGCCGCC
+
DAC1<8,+7&,!>-?@36F684"8#2)F76?F-0.!C$*!<AF)-HDE047@G'(8!/'1/4.(@52">HA=)1;7:%%$/-F6&+0/B4HF0<,2>8G&157A!3#.5;-;3F/!:08"HD!@:*8<
@r6398
TTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATNA
+
A'A4&G=>2C4<9";%04C6/2)AC+3@5$,:;(23$C@1G5<E*A<!-!=@0$=9&"-"1'2@>EF
@r6399
NTNTTTTTTTNNACGGCNGGAATATACCCGCATCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAANAACCGCAAT
+
)'!'(((**'("*%&$('+!("!*+!&%$#+))!$*%#++%'%'!%(+($$(%$"%'"*$'''++&)("!%!!)$)!')+(*!*""*)++#(%)
@r6400
GTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGAT
+
CBD:,2E075)'7;B(-!B;/3)8=(8:@;G9,F5)>D8E/#3G/9)@H*)*.C5-;D-3@-
@r6401
NTCTCGGCATCACCANCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGNAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTC
+
#:@5>/"H''D4#=2/HFF=(<,6(-B+<@B8)4;$+;8%56@;("4C&(B3=G>>8!;B'3=D"@<-?+>,)(*D.#9#@==$"-"$7FG8?7"+9D="-%C/#(72E9G*-@1'(3(#4G@
@r6402
GGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATNTGAAATTTCAACTCATTGTTTAGCGTTTGTTT
+
8D?.$0)570*.GC!*&332?"9;C5?;**!6)-7*B)=;73;>.FB!(@))=8@C)F>4:(?'?9,(/G7*13:)=$83.GF7+2'GG)'841#C1$<%"9+::6F<
@r6403
TTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCTCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCAC
+
F*9G43?@44-/BA8(A(:4!>-(E""F.5!;F#;<#EG+1-*;*DH!HGBD!;;&B1&1-#+6:G">3G#?::>E-69.?6D(%F@EA<F7H3F)=G>3!4&"C&&#&;9<H$8A1:2?;9E(F,G97-C>'<B>,-3F77?79/F8$9@BB#$>?$.?2E3G'2:
@r6404
CNCCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGC
+
&"$/E;-.92<C6>7-5,):(46+>E4=>F*?!"$/$$2$7?&?EB=$3CF;D
@r6405
GTGCATCCATCTTGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCA
+
)+******#&!$+&*")"*&+##!)"++$!!##&+++!#%')'+&#%%'$*%)&&()'"&"+*%#'##((%&(+!+)!!(("'#&'+')($'*''#(%"&)$$+&+!'#'
@r6406
TGGTTGGAGGNGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTG
+
**%)"&&#'(+*%'&$*))'$+&&(*#%*)*"(&$#)#('&&)+!+#)#(#%+$'**+&"%
@r6407
AGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTNGTTTGCT
+
C.<4>&5GE==G""3<F>8/&0$438##C%20>6/GA(9!*2B*$1;*"2(A,
@r6408
CAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGA
+
=:;"2@G6B>"F.@:$?AH@6CC:2B<!)7H$@B9%C*"7',<=))5B<)"A?.C:
@r6409
GGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGAC
+
(D$;8<C@%".%FD;,HF?!7A@8*832D0G@0F#!?3#E4!=7<A4<&+7F<35@9@:59+"$."+A$6G1,D%+"*:*:BA19*@3
@r6410
CGACATTGTCATCATATGCNGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACC
+
530+1.$@<BB%D76<>4)1-=#')+B9:A9C4.#,!D6#C>9/B=G/.D45E6=?.52438C8&!GC781<E5CE$E&D43E89"?
@r6411
TCCCGGCGAGCCTGGCTNACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGC
+
/2G>'HF&&'07*G6:.&@:B):,2>7?26=G1)+HDF&.4+D8C5&'7">0A;?,5->;1H<7%2=+/7D.""H+@@>1C96A<!ED3GC7A6(6<?/C?664#FAH""!/%54+H<)
@r6412
GGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAAC
+
H*C(BH";&0EB6#*'14)0<427:E:3-D@!D3<60?G-!'?B3(5D&20,'?$H%:B)BH+*"E.A!0G27,FB;*/C(2,@G!$B7=#)H,E!!CG@C97H7*01)'87?8F3F24")0!4,B#34;:'1?F&<H:/?2+<<?+%.
@r6413
CCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGG
+
C%"7B7972(>F9F<!)#&5GC)B8+#E?$>1FB.D/:<=+8B:'9?<+;:/-'/@#*;9BG/3<@$H;C<
@r6414
AGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCA
+
//,'A,;/,*B'6D0688-:9?(E/$&:4%<#B$BB7.G95A2?$F)+'GE@!44.),3DD?4(45*4;B=4D5>()13)62>>H+@)*!:6.3)44#!322640437/>G3*80
@r6415
GCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTACACGCTCTGATAAGCCATCAATCATCATTTGCTC
+
A@3))2>-)6>'F;8H+<A'H*6!3"E"7*8"G=-&73H?;2H;=/3G'(?A+1;*971-<57-:GFF&1E=@8A@:&86*@C5&A?F7=2<;83*5-G)1C=*97?
@r6416
ANATGAGGAGGGATTGCAGCGTGTTTTTNATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTNTGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGT
+
(&F;B2+".9)$2F1-2B:"'B>)4A:&B5643(8/@BB:=%HD281(E:?G/;$A)'C";/.<4*4@5!0;2/>325H6!?G<"?7A%41"42#<6;"7HG*EB!<'!D<C2H-8A&7)'5=30A:->0&>>2B6B<32%5E?#-*@,$2!-+#!"H
@r6417
GGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCG
+
9"?&0$>,-)-FE=G?C&;&8AG-401E.)+2-GA,#2C"B-?H)*21,=2+%"%%;(0F)7?A!8B.5;0$2,'=-D8B@"54$"#%C$$64+E;4D?$))/
@r6418
GTTTCACTGCTGGCGTATGACCAAAGATGAACGTTTCCGCGCCTTTGANTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATC
+
B999<G;7+:5*,090H*=9E'-&C79A6>1<>&A5,B"$@(:.9.-EC%30!82:"=A95!0815%G45&3:(/-$%D-'9(/&1:;$,:<HBDA+93H4@57A=H38%5H4/?2$:5/2#19FAB'03%4%EB)A)#4'@;D$EG2;%9B21?1"20;;CF-9@.=/?9=2"<,GE+G&CE$B@5B<'H&%*$D"-+?+G.&9BB'("!*+EFH.H>0,%06%:83>!#-.9'EE/E5-GD6B5:"A82,60$0;G$B6B
@r6419
NAGAAATGGTGCTATTAAGNATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTNTNCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGG
+
"4=?>FE*=>.";'16$:$"*.F&?G2E>5.6B.&':,(3)()2836'$3$!2$/&"<:)9=D=1H"&""+/-307(,+:,F.H/@D=$+15#0.5#9,#!$>A,8C4E<G=F))H0;2<);-($A=EH"70A:4G5;?17<>*=B.2=D)%1FH<+'3A6H6/==@+7%9.>1457<.AAG=1*"@,58:(&G?8)C!/+,?/5=402?-C(3!E&3B'#&/37E455"@F#2:%5!A?7!;<!?.1#5?5='E&A5":+GF20"D)3<*C>(9*?<DH6H%&!/$D,1)C
@r6420
GGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGNTTTAAGACCGGCTGCACGGCGCTCCATCGTTNCACGGACCTACTGGGCAAAAATTTCCTGATAGTCGTCACCGCGATTTGCGCACTCTTTCTCGTAGGTACTCCGTCCGNCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCAGCGATGGCCATACGACCGG
+
++$"'#*#)!'!$%**+'(#(%+!+"&!(*(!&!$(++&$'%%!(++#'!(*)*($$&"$(&&!#&*%+)$%$+""''*+'!*"$(&!)'+*)"$$"$)"$&#")%(*'"*(%#'#+!"*+&!)"%('$"###)(#&+#(&('+#+'%+!)'*&&&&%'%**%#'$!(#)#(%%&'*+*'"(%+&*'!'+**#)'!#%*'#+")+*)(($%"!"(#)$)(##%&$'"!"*+#'+"(#("%#%%)"!"+$$&(!&#)!'++
@r6421
GAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATC
+
>6;@7D?D),G"%5?%(,C2E;.!?C3H%@2AB>$?2'"3083<5:<0%-B:A3*9F.9"6+0267',-=>5>0=%69>
@r6422
GCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCCTTCAGACGTTGACTGGTNGCGTCTGGCANAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATC
+
6-<'=7.3"0@-";83#&0)H-'-/G2D*A&(=D671C+09&C;92F&5C2+B-C36*;3.9##%<"H3:-;4*.,AH*==1!"<DE>;/,9*(!5-6+0#>->!E.$-(8E?H2CF),%&,@@?#=)+C));GD(%(69-'G5*"05G7</'4EA6<2+@3)&#?GC;G*9<17>E*1.=*$E?3$3*B5E5*=#/D*%28&/@;6$?;%?911>/*;+>()E(9!"#0+F0?+7@1+?BG@,0A'31*7#$D9?&B?3A+>@5(6&9'C348982-35+%H=)A!94F*'/
@r6423
CTCCTTAAGACAAACTCACCACGGTAAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGGTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCG
+
=B)&4C2A1H!$8$G-B2<GF")B!3G)?(5(11:"3A5+)8*.(&7F*7!!"G#*+8B#53#8)46A)*F.?3:'G'GD;%6)8;>4?/2>5'$-!)+,&H!;;:BG8#:G6((=%F?E9@%-+;CH;H:+/'1GB?FC&)=<?&:D5(+@;9A(&?1EHE'&+H/+&"76=1*(.(G";F5(!3FD9%%BCG33%H67D%68"/2DBFD;C6/("<9C9%<08@+4>2-4)-'/@80D<8G5/F6,>(3<8A>C"A!,81H("D)
@r6424
ATAANAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAGTCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGAT
+
-679,3+H20,-89GHE9F6B!>:1E2FEB-*)EGA+1A8&G4F-H@.H>$,55(3-'8;0@2&;)-86):?A3=<#+=D$/""@!)!(-F&;C*GGF49&!'G'<*-!%/798H(0?42$-'$%*5#6;F)'15G?GB?%2BFC,@&.9*3!->$E=
@r6425
CGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTAT
+
=3CB;-$H#15&&@23#EC&<?<1B(,6.3<F1F'<:11)
@r6426
GGTNGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAA
+
8!>*$,:=!D+19<%/&43$*:9/>811E.5)FA&4E7*$0<H=?E%".E@
@r6427
TGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTNGATAAGGCGTTTCCATCCGTCACNTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCNTGGTGTGCTCCTTATTTATACGTAGCNAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAAT
+
:?-(8#B870$%+43-'/3$0B:1=.(29:3..C,67/'E(9*-F.3?.=7=.)%,'8C-,=!2<"H)03DF467?E/:%H!)<7A78--4!$EAG*6)9@F=2GC@49%<59AH>+&*':&,:#4=EH<G@H:%FB:>D-52B$<CC+3$D+=;G13$745>?=5'!8G-F6!89BH=80G?.92D=.48(>A(B0FG+**1=7:$..%FA)+F0A2';5?$<;B#@0!>=52;C&>)B$H#/"0A17F17=",!20+.)F*!G;#-
@r6428
TATTGCTGGGTTCTTTCCCGTTCATCCAGCAGNTCCAGCACAATCGATGGTGT
+
<EB->76F4G/?:(F.#G#4+#FF**8=305=E0>G(F'E-0+FG548#D96<
@r6429
ATNNGCAGGCNNTNTGCCNTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGNACTGCTGGAAACGCAGACCGTGGCTTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATTACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGNACAGCCAGACCCGGACGCTGACGCTCGACCGTGAA
+
&)&$%#$**#$"#%&%$+%")"#('*(()"*#&'*)+##%("('(*!'#$(&+&("%&'"*$$%+'$&"")##""$+""*!!**#+#)'%"'&&%)$'!#(&#!!))"!%'#&((%%("$'(!*))(+%(((*$"("!($)#'*&+%%+(*(&*$+'"%($!'$#**!$)$'&+(+(#!)+!&+'#+#%&'%)'%("+)"))!$!&$&")(#!+$*'!+''(*!""(*"#!$+")(+!(%()('$*$+*((#+)#$')&%!)$#&"!
@r6430
ACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGAT
+
/?3++@;88!-'/86%3#)>B+86<7%,!FB+%&1$D9*'>=4&F
@r6431
TCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAA
+
%)21A!7H3A%;7%,G?2E+":H6#;*+F<%B#6;@3G0:1%%9)EG4.%$/-;/>"6E%8*'2ADF-5%%B
@r6432
NTGATATTTCNCNTGCGTGAATNTCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCG
+
&!"$(%&$&*($!"$((*!'#*$+&$'$)*&*#*!&#&%&#(%)$!%))+#*+"#)%
@r6433
AGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACNATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCT
+
E5GH$"<@++F@H5D%*660H7:5;AD=#8-,5#6A?DAH6)?H2/,/D1D&(,@"7C2A(?7H.(2)>.G.;G15F=%)*0<1A(A@<!106"*;03@!(C('(2("07F#;%4'72E2(6$"G&
@r6434
TGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAA
+
HC%H4-*(#EGB.F/)4!B?,&-?1D>'<E1H'(=/@59>8)C"87>'B)=;'=&6*@3F=5FCEC)1!((..;CG(-+E+AHHG0.%+
@r6435
CAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGG
+
D##G:'D/)-!=6#.+.D+*%(1H-&@7>EDA9%$712*!C0+G
@r6436
ACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCNNAGCAAAA
+
&+>8>%*#@09;;B@B<>.@F<42/A+#D(7@D1A3H?B6>HE';!;"CA<?7%)-3C
@r6437
GCTGACTGGACATGAAAATGAGGTGGGATCGGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGANCGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCG
+
0)%0B-&3/6.+(79*'EG?<C9</H37>>7?4<.3>)678$G&'$?1'29+?5D?D9)/F?4#4$+!,;B;;-0:;-30(+91&/E9H!C.F><-0=+7CF7>%H@):C&C">$&)A%9.B4&!.C:?6A?;":H2%249@H67&*%=1F4C&!",3?7B<*9BE@#1.7F28=D$?&E"9<6+;*A;2:'!,,8'%48/
@r6438
CTGATTTCGATAACCTGTTCGATGCNGCCATTGCCCGCGCCGATGAAACGATACGCGGGTANATGGGAAAGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACANGGCGTGCGCGTTGAAGGCTCCAGCNCGTCCCTGTTTGACCGGACTGATGAGGTGCGGCNGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCC
+
+!'$%(&)#'+%#"#'$'(+)&#+*!%!+$$$$'*++!)*$&(&#+($&&%$!#)*%$!!+)+(#'+$(+*#+"!'!%(('$"+$)+(&%&'#!!"#%()(()!"%*#(+%++!#+"))+)*!&"&+"(!(&&+$"&+"*)&*(%%+*"**'!)(%*$"#!+!%'&)"%)!&&#)(%"((#'$++($*+##'+'$&!**"(!!%!!*#("+&&$!#"$&!)*!*()*&'%(&%))*'""+!%!)(*++#+(&%*%%("*(!%&%&++!")&!!%%+''(&
@r6439
GGATACTCGCACCGAAAATGTCAGCCAGCNGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGANACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGA
+
,6DG@,:B)HBA3396<'=-4-!D,C7':=A1C,!??F!F7D9D=;+-5&5'2GD/9.<1*98'!!/CB@'&=16)>F=0&=-0*8-1+CE9=4B?.::?&6A1':!@B0<**G34?74!<B-?7D)9?869)'6)=A:GE'DA"<?9B5G6/2!$'G;4,#72)A=/,FE)>E"@>=4,48H:+90$+*CBE+#'$7=C:3=8%C:#0*!>G"C.+:
@r6440
CAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCC
+
B56A64?2*-2?CG@AC9#2H<,/,%:/(/3&#BC,!GA28F'802
@r6441
ATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCNGTTGTTANC
+
AA9@B1-2A5E=)C$"*CF;+DF=HA/>/G(4.>>7''(:H+6?*F=H@:/$3(;!;3.*8A<.@$?E+:?B:HC*2,;
@r6442
AATCAGAATTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCNTGTACGCATTTGGTGATCAGGTTCTGCTTCCGGTATTCGC
+
D',,=(%5<6@!93&27$,'F.+?>6C&7F<)86-(*92+*7<6=$(@)>A>A9AA9/3D5&C)0C/124"7HG.9:!;&A*F5&#B!"C'"#.*07<2#C%@3':2,29>@.$+=8B,G"$)450C"=AD66-D7)",3$H(G)57E7436*&C$D1@-<<5D='#)A&D"3+48<D34?E&#8#<1D0=,@(&/G9"/C7C8"7!<=@/218+G-;F/)A3A$?;
@r6443
GTTNGCNCNNNNTCATATATNTNCGNGTCTNNAGNGNTCTACNCGNCCTCCNAAGNCCTAGNCNCCANCGCCNCNTNNGTNNCNNCAAGNTNNCGTAGNCNNTCCNTA
+
""##"#"""!#"!"$##$"#!!$"!!#$!#$!$"!!#$"$!""$!"$"$$$$$"#$#!"$!"$#$##!$$$#""#$#$$#!#""!""#$#!#$$""$$!#!!$##!""
@r6444
TATNTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCNGATGGTTGGAATGACTATTCCTTTGTTACAATGTT
+
7)+$*,GGF%?*1,1;.(%'&/,,B2A*,6!CA3+,@H8D:'*0#C0,0A=:<+A,41G7@G+H'96'>H>0$($#&*:3G>;,'8&73G##DC'#!B295<(-<?,659*:GBA'8&=<:68/@%$;7>%7?2GA+
@r6445
CTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGANGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCNGTCAGGCGTTGGTGCTTTATT
+
!+'5'BE"G!-AE9E;$B'6;1CABD>-'?@0-=EF!EEDA$8A*#!25;@.>E(9>+3-24C3)$,!5$:>5*%0A/E!81E;>'>,A'>FA%E-.6<,5+-7)7'.125;G"1+#C;<-A?,3(B356+6-@;)GH%*')D"0():39!)8>B+@3/%E!.:/G<%#:';25(#
@r6446
NCCNACCTCCTTAGTNCATGCAACCATTATCACCCCGCCAGAGGTAAA
+
!%#!%#+))'%''*(%++"+$+)"$(!#!*')%*)%+$!&#*!)%))"
@r6447
CTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAG
+
&'4$)83"?(7E1G?34;;59%@75F":?<0.>(-($=GH&!*@6$*=.*:)"(!6"+3;6E$3)9*C189:+0=,<6;G*#,@</%5C!9FD)/#G5;:D#):F5@/?*H2'*/HB(7'B!=$0
@r6448
CGGCATGATATTGTCTTATTCAATAAAATTGGNTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAGAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATA
+
H/0;<3D3BA?1/B08%2-+340@!"<C9'A@(26%=A3&=6EAF,)8>'27*$D=#2?@+0>1700FGDA)DCB=/%F1-,F;$739%CC<",/#GHE3)H>B:%<F*:75;+>#?:27C0$.&B@";+)0-4FFGE"35%:6+-#97+2EG?'C(";.*782G7E@H*<"*!3%F"-(0?9!+9.7A.D"!!AF/*>*<E2%:$9=:H0C:!7-01:,G'@A8G#>(5(8$)!@(-?'4
@r6449
NGTNNNCNNGTNGGANGNNTANACNTCCNNNANTCCNGNGNNNNAANANNNGAGCNTTGGNNNNTTACGNTNTTGTNTGNNNNNNNNNGNCNTNAGNTNGNNNNNCGNGNTNNTAAANGNANGNTNNGNCNTNTTNCGTTNNACNTNNCNGGNCAGGNACCGCNAGNNGCTNTTNNNCATANNGNTNANGNCTTANCCCGNNATCNNNCNACCNNNACNTNGCNTAGGNNCNNGNANNNCGGCNNCNNNNNNACCNNTTCCGCNCNGNNNGNTGTTCNGNNTCTNTNNANTNTNNCNGGNTNCNGNNG
+
"$#"##"$!"$##!"$"#$#$!!$$$"""!!$!$!$"$!$#!!#$###"$#$$"!$###!"""!#!!$$#!!!#!"#$#!#!"!#!!""!$!#""""!$"#"!$#""#$!#"$"####$!!!#"$#$#"#$#!""!"#!"""$$$#!!#!$##"#$!!""!#$!#"!$#$$!#!$$$$""$##$$"#"$$"$#$!!!$"$"""##!##$"##!!!"##"!!#!$$""$"!$!#$"$""#!#!"!!$!#""$##!"!!!!$##"#$$##!#$"$$#"""!""#!!!!!!"!"#!$"$#""!"!#"$!!$
@r6450
GNACATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTNCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGT
+
%%!''*+!!'%&&*!)&%("(*(*((!'%*+$&'&+$)'""#!#()"!+$+*&##'+#&%&#))(*!')!'$*&*&+!+$&+'++#"'(%++%)'#$"$&$)(#+&(&)%*'"'+#!'(""+*#"(%##$#'"&!**%"*)+!
@r6451
AATCCCCACCATTGCCTGCTTAAGCAGAANTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCNAGTTCTGCTCACTGCCGGTCAGCATCNCCGCCATAT
+
E8?+;?,/0'!9#C?!#*"+7+G)8*?;-&<1:-B-$GE.49EB9>C@2C1:'+C$0'#4#<E=AF;F:F4(8&<@->*B3-22B2(6(%D:".+%)<>%@%/DB)%
@r6452
CGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGA
+
H)@F79C&#G.12:9:*?.:.?8%B,&3""D@(/1<)3(.B7?1C=/<6;(%71#EH+$DC'E52359
@r6453
AAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCNGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCC
+
68."<&H!>H0:C#*!2.,-41+4(-EA/@;>;98<):$G?:0'(0"G@-.(,046>&&CG+8%1FC2)-=.7**86?A+%A(<?,!40124@$B:.*5+$%#F)B9?DBE),$>@)>-B6@
@r6454
CGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGNATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCNTACACGGTGATGGTCCCGGCGTGCGATGGTGG
+
FE=%'05CA)8B?,=;?H6!52C!+%B@:H@:+6D)A@F7$FGAH9C+5+E)$9!F.&!,)8$E3)8-@22#/9B3F)%F=3#?8/4'+1HF01.?,.A?*1,/AA9%955@-3F)/@:17<##969?#?#8C=!6H/B#&"*
@r6455
TCTCAGCCACGGCCCGGCGCGGTGTGCCTGCCCCCGNCTGGTACAGCCAAAGGC
+
;B3;/;>99);8!+@;G46,60!;89&60@*0:H53D")$-C=@DBAC&!60$:
@r6456
NNNNCAGNNNTNNNNNNCACCNCNCNNCNGGNTNCCGNCTTNNCNTNCCNNNNGTTNNNGNNGCGGACNNNGTGCNCNT
+
"$#"#!#!$!$##!$"$###"!"#$#"$"#$!!$#$#!"#$"!$""!$""$#!#$!!$"!"!"#!!$#!"!##""!""#
@r6457
NACACCGNCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCA
+
&E>*-E:%D1+%0#E<.8'5H9!)GE#4B"%#C):&!8?9E%.'.'AB;&,G<".B>#A$<=%A,,=HE19GG779GG-&:+$'-2":)/A*:F#7&227!1!*;;E;$
@r6458
GTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCNGCAATC
+
;-+3-:<$1@'3$6>>#-3-C3=98@7!-8)B$?2.,,9*::6GE&)@'>5>""3!6C=>.%@%.!&?9#"(59.E*DEB9%?+H'+=;
@r6459
GGATCTTCATCATCGAGATAGCTGTCGTCATAGGNCTAAGCGGTCA
+
A!!<>-HB/)E*).#((2C>1F7E0'D)#)&+6@@$6=1($;(@A=
@r6460
GCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCG
+
&.?&"85>!C/!/-@//2&G&#8F$E:!="-EB?EB:8H+$$H6($&-=<B2$2H=/4;7#/3/?"E!>(00"$
@r6461
NACGTNGAATNAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTNCGATGAC
+
)(!$)"")&#%*+(%&"$!)%"!+$&!)%!$"'&+$&#+!#*"%()&&&$*$&$!%%&!*+'&%$$*&(%+)'+%
@r6462
GGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTNGCGGCACGGAGCCGCGCATCACCNGTAATGCGTAC
+
,+?>34HD<.F:+=4!@?@3#A83HF'A/,8A47-17H/B=&D20.CC0#(+)=&C8BA&F58)1>5)E2A)#8(A=+A-7G2%CD4?EC/+#;?:B>;9=,<
@r6463
TTATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATA
+
*+#%&%('#"#)"('#(!'&##&#(*!'(!$))*$$'*#+&!'%)!'*$&%+*"%!()!'&!'#)#$%$&"%&%$'$""%")##!$(#'
@r6464
GANNGTCATACAGCGGCTTAACAGTGCGTGANCAGGTGGGTTGGGTAAGGTTTGG
+
!()(+)+*&+)&+'!*!!'$'"#&&+%)(&'*')(%*"!+++&*'%!"'$+'*&!
@r6465
AGTCAGGCGTCATTTTNCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGG
+
/(?4&'E.6>(,#92E-76C,A/49;7*H*D%E;9)?H-*@&"1+48)$8!)C8(3&6)(2<!)7DD5$?>,8)2-'3H=,:7=(A$E94?B6):B28+>?
@r6466
NCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCAT
+
!>6>>H,=%$(2;?0=1#.GC",6$C"A+&*F.D/0A;)5=C4)H"3A.:+.,@6":9&:*/!7&.3B8HD608,)6?<E(=6;1':2/(=**E#)/=4+#C2GB#?6=")691D7?E%2:'8,7)$-+0':6/(A+9/<$D1:1C349<G6$B(%2HG$"#+:;)F'CA15.=HC5*47+.G%,,*04<0</4+/"$)48%):8'-8%=;F8#'!<5@9/*77"6.==B(3D3E"&:4@F8,60#)D(A9C3($@0@"32
@r6467
NNCAACAGAAAAACGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATC
+
!&&)"!***&(#$!)+"+""$*')!*%+*$)"'&")*'**"'$%*"!**)"
@r6468
ATCCGCCGGGCGCAGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACAATGGTGTGTTC
+
?62#8<2?E/&+?D,#:6A?;00.91/(983B:>2&4).C8<F94535.E@5:@=D4F)?;/(@(C.D)@<!+4<81)3104'=?:?EDH7:/$D&5;2D,0<)"78
@r6469
ACCCGNTTTCATGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCT
+
*=2$>"'*B'*'7=A.4/!)D3=::+@0??=4A*/C213+$(D/E9(/F?:$-89B=C*2=)5B*/-&-65(45G$((!*6
@r6470
GAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAA
+
').5E@,@#'G#'0-8:--%!G,*:3>E;$?0*GC8G!&#HA2B@+1)8H')AD1'2/1!D1GB8"/E.A59$?5,D7#%CC0+E<,?8DAD4,#%617$"3"87A-G59$77%??>
@r6471
CTCTGTNCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCAGTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACT
+
G/&=/4C9-E'A?H,.*B,#-=3*$FH7F5C:22-D;H3(=@$B2;65)6!:G#87#&8:'=1?'/&!#F!D.=*!.&**7%3938?<C?HDG:+D;#($GE18,3>;,2:B90#0+@,BC64(@&=;D#E:6BB<*6'9
@r6472
TGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAANAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCNTAAA
+
'''&$+")(*"+$&!!"'(*"%")*!*$!($"#&!+!$%(''"$)"('''&)+)!#%$$!!%#+*)()"*'%)#)"&'$&()("$!*&#!%&(#!#+*++()(!'%+)(#
@r6473
NCACNTTNNNTCACGNGTNNNNTNNNNNNNTNNANTCNNATCAGNNGNGANCAGATANGGNCAACNACNNTCATTTN
+
""$!$$#!#!!"$!##!$#!!#!#""!!"!"$#"$"###$!$#$!$"$$!$##"$"!###$#"#""##"$!!!"$$!
@r6474
NTTTGTTTTATCCGCAGANACCGTACGAAAGCTCTTGTCGGTTACGCCCTCCGGNTGGAAGGCCACGGTCAGCGTNGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGATGCGATCTTCTGCCATCNACGGACGTCCCACT
+
#05H,7(6)0/%=+<7>F'B+5-1&.G!BG+H>!$(0+)-,?4'DA(B7?,$5$.<0,10"CC-#<0/BE6&D=E0264*H%)E@*9,$<H!5+A<60&:3D15"2A'%%@2B6F3D<*&&22!$'940!?A0F8FADADFCCH/E!?,;!8=5A-D%EBGFH?+>/@<<@(G>;B!9
@r6475
CGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTNCCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGNCTCCCGTTATTGCATTCTGGCCAGGACGCGCTCTGTCATTTCGNCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAAT
+
5B1;24!99.7"+&*3"A53!.8H@*>$>#!,7@&A%B%.<+HH*0A*!:#;5BHHBD<8,6?F063=H+(HB'/=.%#B>:(1A73()2%B?/"61#D/<H:)1;(E+)6&6":0<0.-:(>1:!9B2:E=&1<H1855$)@3'=&%C3%D(6DF$H=#=?!C9061,';'9,D:BH9G*-$H6=53/52*9A;D831C32$:'-7
@r6476
TGAGCGNCTTGGAGNANCGTGANNNTGATGTTCACGCTTACGTCCANACGGCATTCGGCAGATATTC
+
)$'$!&!"(%'(&)%%!"(&'""'"&&)"+%"#"$(%(!+&$))*+)$)&&$#"$$!*#!%!+&"++
@r6477
TTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGC
+
+<:B+09F?>*4<!(63"5?&?E4(*/$)F26>!-'*B/G'GG,G<80<GFE
@r6478
TTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTCATGAAAAATGGCTACGAAGTCC
+
CF#&-!=7A4#<)"2;62G("6.D=?')1+/+**H9:DBBE@?H'++1%6#B4?B)C4-*&G1C%H*$$<'!F4/*(,D"=3F.>!<(#,29#$B1%#:9@:?,7'#!4$>("*3G"2"-G"+E1HH@92%-.$A-#9=24-HA=8(;4!12!*@#H"&0)(A*!4!8;70>)%7%;C>B5#HH&>**2%4E*>B/8$AH;@.$:"@79D9)3<E5=?+>D8D".E7'D<#)0"BF=<B++(->G1/>/53(2)@.')+-H!6
@r6479
TATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAACAGAAAGAG
+
;=*2E@3@?%%GB=;3G=("(+E5&3#?B<@2"#$:.5%6;#!92?G@5=>)?B9/'#-'/H#35'74'%0!563
@r6480
NNANTCNCTGAGNCNCGNTNANGNNTTGNNCNGANNNNCNTTTANACGGAAGGTTNGNNCANANNCTGNNANAANAGNNCNNNTTGTNTTGGGTGCNGNNGCNNNNNTGCNNGGCNNNCNNGGTCAGNATACTTNNNNNCCNNCTCNNGNCCNGNNNANTNNGA
+
!!$"$#"#"$!"$"#$!!""$$!!!$!#""#!$#!"$$$$"$$!#!$$##$$!""#!"#$$"$""$!$#$"""!$#$##$"$!$!$$#$$$"#"#$"""$###"#$""$!#!$$"!"$##!!#$$$#$#$!!"$#$$!"$$!!"#!""$"$#$$!#!$!$#""$
@r6481
TAGCGCGGATGGGTTAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGC
+
4&2)6*3881$+E$66H%3/'0-'!B2/6'?C9:F#239E.B*:$,F4AC?/D**0
@r6482
GTATAACCATTTGGCTGTCCAAGCTNCGGGTTGATATCAACNTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCAT
+
.5&#-HH7!>$C4-(</13".'F41F.:"*A8#G$'5+G.*D(H;'68)403=F;502:?E@3,E5E51<5(!%:$#*"C@713,=6!,G@1FB46*;$$<+D)3$-G$A3B'4C+?<=<(A:.+B='
@r6483
CGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGNGCAGACAGGA
+
--(++$D13(@)A&4H<A(#1D7!A194$,=EA%>):#B@/D;$=+6DFA486@C.>(??<>)F.6.B21,-H))D;?A?)+1>D/)*+<)'DD=@"+H,A*6,
@r6484
GTTNGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATGGTCTT
+
?29/('+C/</7C$>;CH$.*1')<#8!+A>*@944GC;3'7*/B))>CA2$>;8F/E/@6=#-9=?<A-<<<#-4-3+>D?=<CG-=/&G://(=C58!C%+CF/043E)"%+E3445=9&';B/)?/:GG4<01%H$?7D8$:):
@r6485
ANANAGNGACGNCNAANCNGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGNTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGAT
+
&"*#)&(((#)(""&(!("'%('*&)+$!''""&)*"&"!#"%(&&*&)"##&'")%*%##&)'')*&+'")*!#'#%!$&'!##$'%(&("#+%(+*&$!&+(*)%$)#*)'!$')"!)%#&*&")#(*)#)'%(*#*$%!*%&&'
@r6486
GCGTACCTTCGTGGCNGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCNCCTGGTTCATTCGTGACCTTCTCGACCTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTA
+
22%$2/(1-;4:%9=#B0-%/?>7)$77H,G@,?/BG#+(GB/'A;GA#;H;<5++2&7182$',4)$/!7D86$,?2+5'#,;H682>)8=*%E?A=%,B?4/8AGF3-#"$$,:-:2G=,?-31A->E8+&0@41-E%/&H@*".:)>=>:&;D>,H>FB=
@r6487
CTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCANGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACNGGCAGNTAAAGACGTG
+
E;66&G2!7*<#,C@*;/H)-12*?0;DAD.*5/7%:*#F"7=*8(@E=%8?5)!#DBA69)@HE=>B.?&?G?($<)+6>**BDD8B>>(42*+'A:,D"435=+!8=94;&4+#-;.?H#4&/-"
@r6488
TCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCATCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGAAAGCACGAACTCAGCCAGAACGACAAACAAAAGGC
+
F$:GF9#6'GG/G$&*#0?(7D($;:,79G*A97>+76%CH;F7=,)7.E6'%-6,49@&$6E!G&2,H04#"520==H,B.'CA(!69!2$(<2(#A<&.8-8+?;HA1!A#6:/8:EG'$?#$>>:;6$HFA=9HHA!A:<#20&.%<D:.5.E&?H@7@0$$'G3H88C"#?(/B5HCE-A?*6?06
@r6489
GCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGT
+
H4;65*=!H-%@-:'1=3**::#7+%)'48)E)?">-1;?<'>#>$"
@r6490
NCACNCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGT
+
&)$&!+++#%&&!#"$&#%!(#""&(!*$%#)"")$'"$%$'*+$
@r6491
TCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATG
+
;FAE>9>373(#,;03A#;<A)>#8-2E89&>E&.9E74;@8C!6);!F$)"E=D12DDB
@r6492
TCTGAAATNGNTGTNATCNNTTNTCTGANTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCNCTGGAGTGCGANAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCNAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGNTTTACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATTTATTGATATTTATA
+
!!*)'$%#$%!*(!"'*#"$)$'$(%*$'+"%$#)'#$()$$#&'&%&#!!'%$+"+$$)$+)$&)"&)#*%#"+$#'"*)+!$+%(%'#'$(!"($+'"+%+&))#!)%*$!)"%!!&+()&!"$+)!!)&$$%$+$(*$&+'$$&#'""(+*'*+!'%)*"$*'("%$%$'"!%$&&)))#'(++'*#'&#)#!%##*%'*&&(*(+'*+*%&$'(+$(*"()*)*'+(&*"!"!$"+&*!"!(!&!"#$)&(%'%)+!$"&#+'""!#'$"&%''"#
@r6493
TNCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCNACGTACTGTCCGGAATACACGACGATGGCCACANCGCCATACATCCCCTTATAGGACACCGCTTGGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGNCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGN
+
")+((%#)#(*#"!*$$%("#!$*&)+%+$)!'&+##'#'%'#!$++*!!"+))&+("**$)*"!!#%(!+)(#$$+!##(&'#"#"*&(!*&#!)&$%$+!&$*"(('#+')*%)!")+*#")'&$"++'#""!''+"%'(!$$+"($%#"+!'!)$($'++"'$$+#!'+"*&!"#*$"+''&%%#+#!*#&!(*"$'('!+$($*%%#%%+#'+*!&+$$(#)(!+&'*!"+##))'#"*(+#+*'&#)($!)&*('+('")+*"
@r6494
TCCACGCAGTTGCTGAGTGNGATCGATGCCATCAGCGGAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCT
+
+!)!!+&%#!&*#)$&#"%!#&%(#%"!)'(+$%'#+*!!&*$'$!%%(")'"(!$*%!')*!%!)("#%!!#'$('&'%
@r6495
GGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACANAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGC
+
2A;$;7<-$G,*6==@02)0;-@B0&&4;$5B%=981;+0BB$-/+&D4@1-4F*-0:-@H10(;>7"%"-?;D56;@34&,*GC,;C;4E,G@,-@5=8&H5%AE+&6<<F%+2(#>>;**23=
@r6496
GCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGG
+
?$!)D9'7>5DF,C5=/?E;$#54?A38B)&F&16G:3.,'GDE*//*H;$A26(-)B%)!18
@r6497
CCTGAAGATAATAATCGCCAAATANACCAATACTCAGCTTTA
+
*+!&('&+#"(&+(%"$&)&#(()"(*'!!!%()+)&+!'+#
@r6498
NGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGT
+
'8=+:?'*D!):'6;<1;?%0GED*3C59?+,51D!6ADH*AC>)=7DB9#-HE:<84%>-39EG,B5B%0
@r6499
AATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTAC
+
5)+6.90CFB5:4>"-*>.4*/H'#H-G='-$<8-4<+)G17*&4<CF@,7,G)387@)%=D@:''?;A3&3(.C):"%*6CE";,=
@r6500
ACAGCTTCAGCGCCCTGAAGNANCGCCANAATGCCGTTGAGGTGAACTGG
+
1.8>:H<5+#9=#F2&"65)GH.@>6D&(2)99!+*BGC,7C19@12$8(
@r6501
GGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGNGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTC
+
1*G4D"9?+@448D(!+!:GE'D:+<16>B'C2B/6)!?/9-4-0-)44$53AH%)(D92.AH6GD!1B249.3;*"E,@/*1F%HH1-!3!=8.7;
@r6502
CGTCGNTANTNNGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGG
+
*#(#*&))#)!!'+(+*$#%!)#*+)""&)++'*##&)'&$!'*%"#*&#)$()'*!"()%#*+"!*))#'*)%)))&(#'%$+%$$$$'&#"##*'*$!%%
@r6503
CCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGA
+
9'-%F+(30#7%;C8/2A@4.%>/303G0#7>*6)B#=C1"%3+-@@C)+(H''+'6%!$4/-*G::AAG<0"&&(;-
@r6504
GTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGA
+
A5.6%*<06DD*3&=422((*#.3@B++,+;5C5@F%4H$&C3).+-6*;+-1',F-5##!-<+G:8(4GG16
@r6505
CATCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCC
+
?7F0-.<5H)C3%)!>03"E2!0.3A$>&2@3;314?)<3<C&::#DE+3<CGD*-&<;<A'1FD,%$<-
@r6506
ACGNTTNNACNGCCNAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATCAGAAAGCNCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAA
+
)&#"#)""''"'#(+#&("'"&%(#")&!**&%+*!'&)')##%&'$%#""!("#"(!#'!'#$$*)*"!+$#'"*!!''')&"#&'&"&&&*(+$''+"#"!*'!)'*"*#!"&'(""((!*))#$'"'+*%'$!'$%"
@r6507
NCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGG
+
$+.G369#E%=D=&-AC;B0-0(FF8,$@143-4<2+0#A&0+&,*H/=
@r6508
CATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTNCCGATNTCCGTCACGCACATGC
+
('-19B*.4C:!:-/#12!&4*<:&FCCCG.<1:DGF@!A8>:1%$*&D4,BD!3,;(B#%%?A/5039>!4$B<5@19.+%
@r6509
GCCTGCGTATCTTCAACAAGNTCNGTCGCCGTCTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGC
+
<;/C**B-D!06.6>%,">8:1@F+;%/05,(H%7C8&33#H+=:3/C'6E?C&,C9G)5.E?9.5?+$,D..GH-5H*?3G23B'D>2+1"#,#
@r6510
TATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGGATTCAAAATGTTGTCTGCGATTGACTCTTCT
+
4"?)?%'CG9*E8;A3!@?6B+?#2=#5>9/'5E?@.E+42?%*/"/,3C1(-("7<41H.1+<BD509%;@B0
@r6511
GGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCA
+
)F-4E2G$D'<2B@.7!(DEH;6&>?14DGH7,#FE6%*A?$8@.7"'=)=&7)-+#'/97/<>/AG!@C@9!<<%436$25B!/H<8964CA*21D5<;GF'&=/#4"HD=./*)"?'A?80409:--*-@=;:"#!FEFEFB*E01)6(&?G*
@r6512
TTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATCCCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAA
+
(6C!2,B2(7&*)!(F&%)G;#*!HG-*)A4$2D%98"G!(!.%-81DC"":2!<?H-+95&C(0"11.B$7;?3,*;D9?CA5%!7"1&:;-9C3/<>(,:(>%H;F)F>=CF'#:@7?3)+=*
@r6513
CAGNAAANAAAAATGAACTTGGCTTANCCCAGGAATCTGTCGCAG
+
&&!&&'&++#$+")"###&$#+*)*($+&)(!!*(+)%#+!((&'
@r6514
TGGCTCAACAGCCTGCTCAGGGTCAACGAGAATNAACATTCCGTCAGGAAAGCTTGGCTTGNAGCCTGTTGGTGGCTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTNAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAAC
+
':9DA"G5*'E<16E=E+(0!6:#F62C;C/0#A$D'C,"?DG<-1D"H*80)3>8!"A-18#3B%>8)*:986'"/,EA'5#?B$4%3:.=0/EHG"8#-6!!D?+-@B*1*"B17@64$6AA@1:%<5C2",?A>1*0-?37-@213>:==F!.*3E7'FFDC53F;(;/<(:%-H8@,C3B3;4&;"G4@!'EC34A<F*
@r6515
CGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTT
+
(B>338E$C7=E99F;7C/+0>4!2<>-682'B366B8)0*(C?)A:69F%0B'*+H&?<0'##(%59$'/-?C:B>1@<.;=+:23%B><3&(07'6H*0D//%1'4A<=:'G9533@?!1=+97180AHG?*/?B%#%2!.F@087.%?9!E9-&
@r6516
ATTATNGNCCTNGNGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATG
+
##()('*!*%*&)#(**(*''+&##)+*')'("+%#%*"!&%*'+(++#(&
@r6517
ATTGTACAGANAGGGCAAGTATCGTTTCCACCGTACTCGTGAT
+
(9;$4'"38&+-!9!;!61@B-/;:<FFG#?)--!5'2,:D);
@r6518
AGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTNTGCGGAAAATGATGCCGCCAGCCTGACTGATCTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCG
+
477>..D0A$?=7BC%D&*=15:80.G;$)F5?#$>?<@+=/0C=/(G?=,8!<E7;+%.1B0D#"9'@-)$$<DE,?,3@8$,.$:)+"/)>E)C2+"86H3<-<6
@r6519
GAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACA
+
9H<D#FD2$,,#4@F:6B?;?E)0",H,A19;6D((55)-<9@@/*0-2=G/%9*8H/'A#.-EHG4@<>66%7GG0)92;=8'51+'<
@r6520
GTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCG
+
?92D627+=1>1ADE$+C11C<1<(>8;+BA9.B$(,7CED*3@B62:$A,=?1$GE1*."4C1#D#G?G>B0"#+3'!(8HF1A:$>@>$<AH?A70-
@r6521
GGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATC
+
-F7)=-(4%3!(@<.E8=0$%562E3('+<3AC>?6.!8;68$@?:
@r6522
AGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAAAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATG
+
)8?:(8(:"4GEG)6?/AE*,&<8E45DEHB1%3>4F,,G!!<'H:!%<>.B#H:6>%H2354+&C50%741(C$3-=*=##!/F2'A.!(/6!1"
@r6523
TCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCNCAGAAAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTNTCCCCCTGTTTTGAGGGNTAGCAATCCCCCNATTTGAGGGATGTTTTCTCCCTCGTTTTAGGGGATTTTCCCTCGTTT
+
<12CB)-5!?3'&1.,%D%@E$&"/((D<#)-A2>FBA16">-6'-;;4%GC&C+)#9>?:+94(%!$48&E'<<H%5FC!<5.2E;$CG(:H>!5.,2F>*/HHFH<8D4C(8HD%=(5<08,1):.12=&!AD6-*=G-..1/">.:D=A#.$B3?,D?!.A:2%3@3FC$<(8GB?<G0'!"A,D*AE%FHG1BA'D48<(!B#:"H!GGC,6'G<:F7&76=&9&7;-"
@r6524
CATGGCTTTGATGATATNCCGTTTCAGGAAATNAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCT
+
+<-#/G>9:=4:FC,5+@'>19%#A92H4E+,0@H)",8AA+7:AG=@++B;'?*;G(8#C;=9%C%7
@r6525
ACGTATCACCGTACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGC
+
-F+(29B-1(@D2*(H%@<?"0@>79&&$6(CE.+CE625+E;//5/#H56G7&B7?;5?7(
@r6526
ANNTTNACGCNGCAGGNGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCANCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTNCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAAGG
+
("$)((')%%!")&'$%#(*($++**'+!+(*$!+$!)'#$%+'%*"!'*"""""')*!(%&)&!"#(&+&'((!"%&'#*%(!''$'(+!(*$"$++*$!*&'#"!&"*+%"(#&+%"*#*%""!'*%&$'$%#'%'!$%$##!"%((*+##!")*)$+'(+!)("!'%()
@r6527
GCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAG
+
-3'H#'3".?0E(F9(-:.E+E$C&F;H-&%,/8:>FAC"B5*E*-AD1,:08B?0D:6
@r6528
CTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGG
+
55E-/E;!,+E@E&6!79&@1,7D.):7,?C)1EH=GF/).%+-/!=1+B@&95'*B#0+*0A+'8D7/
@r6529
CACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCNATAAACACGCTCGT
+
8$():!B6676;:7$/0*)'.;;AD*,C!B'=H/CB4*HHH3/<A2-;)60A%C<:>$'B("G4,EC!@+6GEH:H<5GD<"$*FG+8F4/491<:%@GC0;"<"3?9*%;4,$#42.#59'GD'GBH6B:;1+%
@r6530
TTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGC
+
/C0##/:!=*GF4,B;-52:G+/;-A=C+?E479$,D4283%)B+;DF9=)C6.!D>1*D#E)=;:*(8.@<E@->5G/<4-+:%$%4<3)(?5.:@$19-:A(9!H<('40GH2359-9D//*%)-@(>2*2A0+>(9GC)B'C,"C9@@%/"4G10$%@)@0>B455"A/(>HD%2)&=D12)6D8A9.?/E$*&H79191,)"1#-*A&0B
@r6531
AAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCT
+
!E?B!))'-58=6DF91?5!";2!&G#1&$%(20D>39"#<$73;=C3%FB;H6%
@r6532
AGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGG
+
D05697??B!"*)E=")-'3G410?#.<@,,>?=:$BB8&7
@r6533
NATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCNGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTT
+
!*3C=CH?%81%"!G43)+A;)?5:8@;,;4:@4)H0??'.0@'!;""B8-!B)1':!G*4(6,%<#E0D)D>:6;GHB%C59EF*0(D4:@70;AC&488G$H*29=E'#4
@r6534
GTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGNAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTN
+
DE#0.FEB=96/C30"!F3A$!660B8<1D@(%<'@#+BC$#-A&=(H@8?(:%."<A*-==>1@@9-)>D$9B*>+&/)%6G7+*%C%?9F;GFD!"CD9F<@39;6</".!1')E0%2-#!5E=4"-E6HFG>
@r6535
GAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATA
+
/>7;/260#=&>1=B"4C?3/BD!&/:AG5.1C>1B0;%,;6>%A0A+,=
@r6536
AGGCGGATTTTCCGGCAGTTNCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGATCAGGTGCCGGATTCAGTGCTGGAT
+
-B,26?3+1@D30%;<)7/36D)+9%H:9C898.=!=5-.40"A,C/"1>A.?6-@'!?2+?E&99,8)-7!"&G&"A*8*%B11C(?&!B@'A&<8H1;F>>E!6)"5C.G&G15BA%7?',%8,."9#146),=$
@r6537
CGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGG
+
.?5?.5.(F.80G;&!/'2=9$'6;4?H68&C@G%>)=*C5*(25EB:7
@r6538
AACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAA
+
-F7DG!D35C)48G75/@,#&E72;7!&'F>+DB7+DA%6#$G!</?FBH4=$49:;1F2=G?,9.0C#D
@r6539
AAAAATACTGAACTTCGGCAGAGGTAANTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCA
+
8E*@.F0*A,<H7??;1,!3:%8DH5%=F#"00)/8D.1"52$B6'*).H;74-(?A:9*-+$;*$=9/&@4H9G!?
@r6540
GNAGAGCACGGGAATGATCCAGATTTTGCTACCACCATGACTAACGC
+
($''"%$%+#$'"%*'%+*#%#$&")+')'!*("(""%)%%!&(#+(
@r6541
AGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACT
+
0>&7)%9B9D+1GGCD,?-@C92+A6<>9F@0"$=1F->>3,B!
@r6542
CTAAGTAGCAATCTCGCTTATATANCGAGCGTGTTTATCGGCTACATCGGTACTGACTNGATTGGTTCGCTTATCAAACGC
+
!57@E+4:1"F"CA.<9&9".#0>3;1B3+FG+*/5-0-79$C!C2;EBA)BC9@."E:/':@'3,%EF'$FC?<,G)$=$
@r6543
AAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTCTATGCATTTATTTGCATACATTCAAT
+
!+""++%!*)++")%$%*+')($*+&%+'&)$+$&$&+(#%#*&!&#%!"+#%!##&#)!'*#(+#(*&+#!"$(&%)%%#"+&)&*+(
@r6544
GACNCCGCCTTATGAGTGGCGGCAGATNAAGGTGACCTGCGCAAAATGGTCGTCGC
+
?@9:%:G504'*:+,30&#,)'3B>H;+DA;8063AH.'375&?#9A%353E2ACC
@r6545
CAACGTTTNTNNTCTCCAGNNNNACATCCCTTGCACTGGTGTGTTCAGAAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCNCTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTCTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATC
+
#'(!('$$('!$#&*%"!$&&!"&'+$'+')""%((!*!+'%&)&*+$#()'+%!#+$"$'$%!+#(!+++!$#*!#*("&'&(%$'"%'*&)+!+$'#+%$*+*"+(*(!#)+"))'(&*!&**'#+%!%"*"!+)+&%'$)((+&"$)$'+!%*'*("%%!$')*(+*#$('+")(%$+)+!&"*#"&&&)#'%()!$%($"!!+$+&(++%!#"(&%!+$+"*)"&)#"&"**%##&$*%!+*&('!##'&+)+*%'*"
@r6546
CNTGNAAGCGCTGNGCTTTCACACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGCTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAANGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAA
+
#!"$""&($&&!%#"%"*(*!)&*++$$!&%!#((#&(&(++&")'#%*'$&%+%#(!"$+''$&%%"#+&&&&**+#%!"$"!(!*"*#!**$%%$%'$!(#!$#*&*(")&$'"'%()&+$!&#+&&)'%"*)"%#*!(&&'!#!%#*$")&%&%(#%$!&"("+(**+%&!$'($+*""$'+'(+'*#')&'*!%&!'('""'!+#*&+)(#$
@r6547
TACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGG
+
$*+%*'&()%**!("'*&%")*)(+++*(&))+&+&+&*(&$*'&(&+&)(+)$$'(+!*+%+#(!%"#%%**$)&!$"+&)
@r6548
NCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGAGGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATNCCGGGAATGGTTTCACCCTGCAT
+
&4<F=&4H3'(@62%E<+F53??<#6!)1-%9%9B"/9?8;65!#0H!@&C5%C:"A8%%<=8(@-B>'='!E6#;"CH1=D"2E)6@D@$,4F)/>,A1/3#$,B,E@#&(E-/G+>)%>?0E")99&8'(/4<?4G,GF""5G3;E3$29%?'B#(B&4C"
@r6549
CTCCCAGCCGTTGTTCGGGTCACTCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGA
+
98-0$6+$6B9(:DG*-E0-E1:F7=2@,('B8&E6*++;+"<-;4!+&,3-#17'&"-B!"!B=49F"")(G<=EB,BH
@r6550
GNTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGG
+
)"H8*>C-@94412G#:'&?,B&)7/5++3*%D5(:B?'F7FG,69#6@6?
@r6551
GGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATANAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGNCAGATATAATGGC
+
>&&H#BHG0E<C!,H35$F;79+4H':=+7$5*0=(,:*(*(,:E<?:E0C2'&>/!37!>81."10*B;%GB-'+%E>;E,!6B,3%F6*:H&21)D?A7.027!88<D8D:@3$$%<6)&!".(#?.9!*GG2-34:B$(>AH!@B;#?E:3@,?4>/D<,@2#G16A;2>G9H)F?#5&,A
@r6552
CCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCA
+
'&B*0/!.3;!8998&6<(<".04!7CB#99C2GB7;?@(0D987F+:80@'%085"H-627F082:2+5+"6H73?0-=@#-7&
@r6553
GTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGC
+
4+(26>86<'GA*%<3="A*&D!4F0@@!0&/.)E4B2<0)7'?B)9#%"7)H"<0C<%CD.&5C#G,B"$<1B%H<)=@/G?&1=@-5GE002(.7B<"(4$'
@r6554
AAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGANTTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAATAATACCAGGACTATCCGTATGACTACGAC
+
'(.9:3>ED**4H$0CH;'H.#G6A->:$H,"2#'$)25B@8&!A=5)9:-,*3D,?-1/>@FD?+5$1#*A(29G"=-!"-!0?5;,"(>"88A+4DG1)DB!:(1'H$;1+6G!7%/:E*AA*F"<3
@r6555
GGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCAC
+
C726;$H?:'!39D+(29%E;11H@?<B?76>:2CH;!$4/972?#-;)(/('>7
@r6556
CCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTANCCGGGGG
+
2$B39EB"&*:4D<4E(>*7CE-H%D-<&3)<+FHF!D%C/+9(F;6F<94F')?@282
@r6557
CGCCATGCCCGCTGACGCCAGAGGNAGTGTGTGCGTCGCTGCCAT
+
$A?@3(-=.5?+1*5C6$!+:5%(!D,C:1+,,,2=E'0H2"4,D
@r6558
GGCAGTGGCGACTGGCGTACTGACGGANTCATCGTTGGGGTCGGTTATAAATTCTGATTAACCAGGTAACACAGTGTTATGACAGCCCGCTGGAACCGGTGGNCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGNAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAG
+
3'/+?H5D-=;/1CC#-&!9H6F/;>+8AG3',;23-C"+/.*(3@%<9C1,5<<:C:HH<55-G>G'5DC%?F9"@<@:6;H%.2>='B$*&E&2%0'.HED?DB8G(EG.H0/7'#C-F1E8(BE3G-@!4;#-%5>@C55<@;>D85<E5=+8G2C/-"4!0,!07+7H<70G&:#01:925+8=4E2C/74>:
@r6559
CATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGT
+
).C#G.!./@B.>?-''H*@F@&+6(9&(@B"0H(>D00:?F85&@$9D4#:>H3-)+@1:*1D.@28;3</F235:3@;F-45$13=(")'$G6'>-8/C/%HBG,46/6;<></08"A+E",G:*-95/10!$(,5((&?(""F
@r6560
TGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATNTCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGC
+
F0<FG':)<"G:6!#H>1.-/$.714&8!(<+?7($97<<2'-8#2=@52$0E;A42E4A8=:3+%EG:B#D9G(''@H$?>?:##7B%&
@r6561
AGGATTTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAANTTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTAT
+
""A*,;D04@A55.-=H339-661?E5F1'E+C07;='-3&H7"D:*7.52((F@</A9$'4=;F&9,%77:?D7;'BD"D%/F/F<"#9*#9%18H25%(2E(?.&G05'E+.H?&&##-+4<D$DEB"DH(>E,0-#GCCA7%AH/@(G?-&<..
@r6562
GGATTCTTTCGGGAGATANTAAATTTAGCATCCGCCCATTNAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATN
+
',0E$,36<A-/(@F::1&G,8<-D@?H)4:+/5D)60B=>?D0,G.,BA4AH?#36E%'.:F/84%H295/:+6H#3;DH=+A2."'4;.F(1+*+'>25&&,/+FGB)(&'/FD3B74DA>*,#>.(%2
@r6563
TNNTCATGGCTNTGATGATATCCCGTTGCANGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGG
+
*!$*$+'"%'"!#'&()$"*(!&#("*!%((+(&+!#"#&*+)(!&%*$&+&)*#%$!)$%&%*++$(&*($#*#*((%%(!($$"
@r6564
CATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGANAGCGGTGCGGCGCTGGGATATTACNTCAGCGNGGACGGGTATCCNGGCTAGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTNATTCACGTTTTTG
+
,/H*5(/.<24./E)>%,!0&:'#D&/5=-=9$8&BBC$5F27-EGC!">;.G05!@.!5;C63%23D0(E5A0/;<A9;'&7B0*<G#4F*'.C->8D**B,;-/A<+)H1+B0<H#-G6@<6?6";+F0!#CF,81<"<'2H-F6*C)1<'31#+31/G<0;#%A'(1D*0>B8(+E//("65
@r6565
NGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACGCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTATATGTAAAGA
+
"<23&+B&8F:<(/DD&:C60+-;='(2F48,2('E=B42)>3D""C8*@4,$-@1@2H149-&"@C:41%<?#&DG?#?3063?G9-91,'F/)=&<<>C"6G.>F;!3*5("GF=HE+A'FB#;/D?9<G)F8>"B<(8/DH8<5'#->$
@r6566
ATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACA
+
<>=>C4;94;<6%-06DA+-+"?!#3>6"12/4+#F/92!708"3:FA1+6(!C,%?'>2F+9+E$.(("!(E;12&&7
@r6567
CACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTNCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTC
+
28<8/57@0E"&.@7<5*FE7,A+C)5H/>$%75$$"!CFBF>."9@>AC(+%=2,CCGH20+0?54F*D=?;DCF%(:F+7/:!5,$HE/2
@r6568
GGCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTT
+
($3>62+A!,@"D">++BCCDFB1E4)2++<$*3.H)GF&<<HC@#BC;?
@r6569
CGAGAAATGACTGATACCGTGNAAAATTATTATCACGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGA
+
C,/&D'!)=@F6*>C%-#<0$HD)%(%-C*E@?CD$7?H427G6H43963AA@G8D8=G/*F%+:>9;C11&,&3:6$*,"3=?74;2<+6=><$@;!=(F.'=<@*/=:4.:>$EA4C$A+->0)!
@r6570
CGATGTTCCTGAAAACCGAATCATTTGANCATAACGGTGTGACCGTCACGCTTTCTGAA
+
3!E612+9#8=07-?6;%.(.HC1.00/$;7:<#(/9?=B*%4@2*$/..4#/""H>C?
@r6571
GTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATATATTTCTAAATCGCCTTGTTTTTCNATCGTATNGCGAGAATTTTTAGCNCAAGCCATTA
+
:3"$G06&$#F"'@<-'8=11";,;H.0>.8-3<D)3'?(!<7FA?$B@371)##$BB(C0BA=<9:G@=GGFH"?"G+#+1:G@-A@(HEF;,'
@r6572
AAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAAT
+
/)7G)*%B?G'5$(:C&?H"&&FA@!A4B/%-8*"*3HG>E3748
@r6573
GCGGACGTGCTGGCGGCGCGNGCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCG
+
<+-F8,05,-./<!42%742-#9.415,AA2G2*9)+:2CB<&;C37*8F600$E/>8#(/(91=2<"5"<"H3*!-$;3F'H-
@r6574
TTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAANCGC
+
@G"FFB$E/)'11:G>5E$+/E%6?>G-D7*"!>#4,6*<9E=C/29;<6A555F=0#!
@r6575
AAAGCCGNGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGC
+
A2)B4F+(%H!-.!;.B@85%1*$8,B(5@.FG3$?1%A&AH2;$!?A8+88>-H.'1C=!!9:/@%
@r6576
ANNNCGNGNGNCNGNNANATANNNNCNGNNNTNNTANNNNTCGGNTNCTNNANNTCGCNNNNATGNNCNNNNTCTNA
+
#!$"#!!""$"!!#!##$$!$"$!""#$"!"#"#!"!#!$#$$!!!!#$!#!!"#$!$""$"#"""""##!"#$#!#
@r6577
NTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGT
+
259%%,>"-&2*D:=><2$,6B9>B>;923'A39<(21,,&&%H0/57'-@A#(5D9(>>=4HC,.?.%0"?,(!2,G=,*
@r6578
AGNTGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGANTGAGCTGGATACGCAGTCAGCGAT
+
%(%%&)+)$$)!!++&#!"'$*('(%*+*!(#)"!$*&%&&%&!"*&$'()+)%(%!+((()(*'#%&&+*%(%$!'!%!#'+%$$*())*)'!!'"")&)))##$
@r6579
NTGAGGGCGATTTGTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAA
+
&>B+-9,#7H??"#*,:"5A%B:1C*5/974GF80)4(A'=<D3G-7"F-.(G5F:-;GEBB)G)<EG2"?.4?(?-:>,;D4D@3$F#?"<GEBC0!@A%*<0<*4D?&GBGF@'5*C3<>D
@r6580
TAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCANAAAATTCCGTTGCAGNTGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCNTGGCCNTCAGATANCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCC
+
@)+0-798=4?37@2B$'0)58=@56,G6#:;D>?"+##28?'EB#G"274FG&4/F5?6H'AA3F&=6,.FD*B/C6!);!6+/:.&<CB>"0C<)*):<49)7D0(3.H3$@9;7A2#;E38,4?/135,'#%";82*5)@-.==+@>$;-HG<?4;2!8H+2'7.H,(;0&/@EA<(2@7+F$74B54%&*9?0:AB)DG(::7&?,><@G78B'.8=-%,4
@r6581
NTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCGAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTAC
+
%,A4AD5-0AA=0)('-27FH/B5AG"G/75,39$2!>-5@11+D-#*ADE'(-G?0@B#>9%&18A-(,,1(8#+=+,?A=H#(9,:'>F95&4;*B:=$:0C986&<
@r6582
ANCANTNNGGGCACNGGCNATNCAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGATTAACGGCGCAG
+
)!'*#%'"($)$")"''#**'#&&+&''$&%*)'+$)#'#+"+''$#)&)$&'!!*(+%%#!$$+%*%")!*)#)!*'*()$")&%)*#""%'"%&*%%+#''!+$%&(#$%('#
@r6583
TGAGGTGGTTTCCACCAGNGCCTGTACACCGAAGGTAAAGCGCAGAC
+
F3(88(.'4?4?,>(@)5*6*++)9F&1--<$-6%4?;+5=."0<&*
@r6584
CGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGAAAGTGAAACCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCANCCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCAACGGTACTGGAGTCGTTTCTGGA
+
G&(4<$C7!'FD74)5$"%@$4/722"<2685,ED2%'*2%$#-1B$?D2E%7(H?C"2531.0,1<+E4H",A3B()5/F"9":AFD?CE?8?<?/@2?+C810(A$!G)E14).$%7*3@?:7!$F(,2$9E$3G0?<!83%-((/A!#-E'-6C291GB7:&AAEA8=)?;BD$*.G>5(<5?@1E).42&82,/&B$>D:!<%%"35+-.!@A10B
@r6585
AAAGATCAAACAANTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATNTCAGCAT
+
5;@(2"!)/=6<8>=*7!7FB:9F@G>G>(3*5947.8)+#>2G1?GB3'<D<%&>%(C&.D=9150'BCA
@r6586
GTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTNACTATTTTACCTCTGGCGGGGTGATAATGGTTGC
+
/1071#3-7,!@?='"$H/=@'E4A,*(B!<';65)+F&:>>!+E6G,AB<A">$F)1C>!7'A+8*(/0*,CB>F@;/6<E-H9?$3:?@,'@5%%A"-*7:5EG(4-1#H
@r6587
AAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTATCGTGCGCTAACTGCGGTCAGAAGGTGCATGTGCTGGAAGTTCACG
+
'<,(DG1-H"/98>5$:(D*!6="-*H390&95GDCB,%$:--363"C=<B57HG;%&CF0A:-C3&!67.G0B.'5$G;0?F/?'/-&%%=3::"(>CH;,H0!D*'B50-/F+0&5B;G
@r6588
CGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATC
+
,%1$#*(-D?H0$1)=3$CB/#9.3F,8B0@:$68BF9%A;B@:>'$68F7.D=3>(A2.6(+2G"BH>"5A
@r6589
GCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCNCGCTGTAAAACACNTTTGCACCGCGAGTCTG
+
$'&+"!+$(*'($("#$%"'&$&!&*+&+")%"(($)((%#+*%*$#''(&((%"!++&))"&*)*#%#%("&*+'!"*$"++%)*"+&+&)**(%!+
@r6590
ATNGNGANNCTCCTTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAANAGTTTCNTTGGGTAATCACTTC
+
&(!&"*%!'&"'$)+*"))*$+"((*!#&$&*%&#!%*+#+$%"#(%))'#)*"'*+*&$##%%)'$"$&'(*(&"#+&$%#&!&"&&!*#)$("'"*#)#&!!')&#')+$#)(+$%&$#(!&"!#%('#$'%(
@r6591
AATACACGGGCGAAGAGCTGGACANCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTTCCGGATTTATCCGGTGATGAGCGATATNCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTNTGACTACC
+
;%;$-/1=4)'&@:(10HH4?E?F31&7'47BGFB<%A:EAGF!?3"6,AD,=H':E5E(@7:97#,G5-3H3>F:1>,=D1?.8-DH??:C,/,B9=/>A$6E%'>"@3"'6+?A,79BD2*"9H7><*#+F<$</H4E3#)2?<+@-4"@9,1;"GEA>64<+D:=D/194$$70'25#B,C*DD.#
@r6592
NTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCTGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGG
+
'+*(&"+(*"'+&*+)&$&%#'#*$%")"!$!'(!"&&#!)!*())')*#(*(#$*("!))&(#$*)%)#'!#$$(*"&%))!"#&##%*""*"%$+"%*""'#)++%$#"*+!%!(+)'&)$)*+$&!$&&!%%$$&#+)%&)')('*+!!'"#%#+%!!'($&"*$#!%*"()&(!&*(#))!("*%""""#!+%$&%"%+!$"!*!')+%()+%&#(*!#*''(#!%#(%"%'*##*
@r6593
NACGCCAGANCGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAAT
+
#")%&'#$("$++)&)!("%)"'%**$!+)'("%%#)"***!'"%!!'%+!$'&'(%'"(#$+#*&$*&&*"+!
@r6594
NACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATNCATGAACGACGTGTTCCTGAAGC
+
*(/A98$@4()2?18>$(13-/CB(!2&!#2,$CB+>3+9H9+?@'=:$06B8F6&944#@8#@G0-H9<2@<"9@(H"
@r6595
TTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAG
+
G31*+>F)6)'&A5H4(H/;B:)0*,!G@.,<%/<+#.3$:1
@r6596
ACCGACTNATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTANGGAACGATGAACATGAAAAGCAAAATCATCCGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAA
+
B1."54A.B$53)"6D!815#*C!?6>ED69,6+?=EE;!G>/'B6$2,+<3?)5('$#A!08F9>7'!<BD79(%;F2"$985A0-5#<!C("07E=/'1*)E)F(8(+3"5=C5:05E>6,1;8(:<$!B$.B"9"4&0;1)<-EHE=
@r6597
TTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTNAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTTTNACCGTGACCGATGACCATCCTTTTGATGGCCAGTTAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGNTTTATGATG
+
*60%@C<H/;>B:B%9#=6>3-++2/=0;'3-@1D-5#'EEE%@&HG43(!G+4B!<1-;2150%(FA$55"FF-4*2(5BF$19C77@)$0/6+3=;7.:'7H37"G=8#*+-582(G&0C.)9*-:$!$!20EB0C@?:1,/>0G4*.7;B"252/,;(!F61C<A??+#B&-#=H7(AG=+C,30E%5,2-&?#9+)$,0",.(')=3?;1'&7:D;="
@r6598
CGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCG
+
BHEE5(/8G@97=*;4714);,9&(!-;;;%&#&=:.<E-D+0C8<A##HB5-3;06$39&,G;53.7G"=&;5-%AF2$!>2("107%%D#.=6(54B$<4A&&DB210?+E7,5=4##D.E&A@20%!7@.086H)0<"6#:4C52'"*'4?H;9#"H"A5%5<2,-(=8.$80794""132AC.%+,
@r6599
AGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCCGCNTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTG
+
966C0:6)/822F*%H(+&16,<0B@&4A(66*.E&C)8-73#".%8BC70@@!D0"C4)E06G&B("!6B9F.G*<'E*.)2+"+;5:HD+7/,.@%E671=!54D59A76$=:2E==7-7#A'=514(A-"<AC!*5)/(0HD1>#B>'+#50=B>'E6(%;3;2B(+&9?@##.<3G11,+0:''8FBH-BC(+9;&@B5HEE16$0.B
@r6600
TTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAN
+
"+'$%'"+#*)+(!')!&*%*!%&(*#()!'$)+*(&(#%!$')##+&+((%++#!%$(+"'+&+)"##))'"
@r6601
ACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGA
+
6F'!%8:2&6D887/#@(F&B;!7B?;"0)BG'C=6;,-("!=/8
@r6602
AATATGCAGTTACCGAGATGTTCCGGTATTTGAAAATCGAATGGTTGTTGCTTCCACCATGNGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATTTCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTNTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGNATAACCATNTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCNGTATCCATGAAAACGTATGCACGTCTTT
+
5-%/&C/:'"#8=':2<@5A/;:-<,1?$)!$%76A(<+)8*)8"6>5)D(B*(%"/G$6<HD)"D+9<9F%@.!!B*.E5B<A+$2B:E)!8!67DG&7E>CA?*$"&*:;";2DA1=607/%#989:G!'"3&!3=<H+""-#9E"*(D5A((:$0'(A*C@)F6<>)/<>$A+=/;"$:EFE5E:=8=.#).;;DD-4)HBF$#'==@$F1(/B>C0@68F:E@0E.=--&<?,G)D0#4=.(B<8>F<&E,:8>D&G4*:/"H3+.C92>"$*4.F8CAE%"19="=5</?6A7,;GB-.C@E>5H"E6D*+@E1;&B0B!G0:/E#57G*>?@,8D??C1/%E',C'A,*21BEG1H>'#8''''<.+,:#.10(-8;'8/0$00,4/4*D%.#*E*%2'&D.C:%>1D<4%+%7@2(711!&,(<//+$%68>8&;#?=43%2$-15:'@>&G.%-&&+>1&G!.$/D3&5=**0$F=
@r6603
CCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGC
+
GBD=60-!B#2%G%CA.F$*>=.BC:?A2AA9):4>$"H;1(G0D?=":)"/146""9?=35%72*+"*21,E*-,C+A:'<D;,G6,!3:@D0A2&0G@FEE2!6
@r6604
AGCGCCCATACCGGTTTTACGTCACACACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCNGGCGTGT
+
?=H&@=!&2*E2(G.),67>;)DC*/B=."-9,;A7=%)84.:7$5A=EB@.30HB&:2+668C1C9H#-E#3:(B,E)$%=C*!
@r6605
GATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCG
+
D'G7%1&$1*'?7<77@82&D97&%(7/#)+A/,6*>C"*5'52C=CD,0D<00F"/36141-F7H8G-"&,42G"(B-&$!6&:)8:F/:C;D
@r6606
CGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAGACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGNAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGANTGTGATCGATGCCATCAGCGAAGGGCCGATTGAA
+
A,-"*%B,&=B)&%@G4C<"$33(E)G6/?>>!940&#.",??;9E7:>E52#-8/(-;'@&51&()H3B2963&%'H+@>E<G>5ED+19H6E(FD(%&(;D=-,B%D4C166>##?/)H<1'&F-01+H%B9%A!#$/"%:1008,3*!B2A"3!54G/6F!!7!HA<C=:0,/-%F/H4+H-.38,4=D?/<5+>DD"C<;?0>)%,0=:<754;8B"-/02)(A#&E.8!B1==4%@"&C0:G:5)&!
@r6607
CAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAGGCGGATGTTNCGGGTTGTTGTTCTGCGGGTTCTGTGCT
+
;;!2A-)5+<'(%+5<,8F4++#'-0A>39.*7AE7(!-#&>+G*.E:)5&'"E1&06@DG7+,;/+%?EB0GEE?<6+D"?C6C6!F-64%+0E:A)011:(<$6$E&E5H.:GA0
@r6608
AGATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCG
+
*!%+#+##+(%"*$$"&('#!&(%%*%(*+!!()((!)(&(#'#'#+*)"'%$*(&!$'!*)%"#%*+))$##)(#&"'+*$+'!)#!+"**!&!#'$&*!*%#)'""
@r6609
CTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTNATTGNAAAATAAATAGATACAACTCACTAAACATAGCACTTCAGATCT
+
D4,%"*@HE2/@-GA;08,G*G6D41(5(0@;,%7@/H#;C6#?1%+D?2(+'E9D*GEHE><1-)''%D?8".B#!.6!(4/37);A#*86
@r6610
GCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGG
+
3E"C=@*;,<-%D(%38/G=/5&-A"F@#F?GB8'C,-4'#G4#A;0&B#'F4HH-(5B
@r6611
ACNACATTTGAACANCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCC
+
*%"&)*(+'$%(''+%%%&)+#+&(+'(%"##%)$"((&')$)"'&!!)'#!"+#(&)!'"%%')+*$$!*+&)
@r6612
CGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGG
+
4&&8:*GH8*+<AC,E:9;#8>9385!,>H!*:4,3#"48%:)@E4C(G88$<-D@/+65$00=EEE#",/=/00H3;>(1E8,A.=<*;-$E(C;AA.9=.D29'#00EBB(AF:0"35#D=&E<&<H%%5
@r6613
GCTGGCGGTGAACACCCAGACCNGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGC
+
E&D;//@H2++D@8+#';H0>$:E8E9=***"=0.9-G1@"C5?5%0+:=)25A92H8'@'4#9E7F#.0--'&
@r6614
AAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAG
+
<#5,)EG#6*C(6H<)/3=CA7BC?G"CC7B.79<=G'A1>6%1?9D=@&B+1&2E#7!F70">2;3"<C-(>9:!,8@B+465/$:424'FC("3)6-@&A.6@F<%0#.'(A:)@D
@r6615
ATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGAC
+
A/;.!?4)H%%*($E=)0-FFBD29H9)0!3!%;H?@0@#1:%3E)A?"
@r6616
GCTGGAGTACAAACGCCAGCAGGCTGCACTTGGCGACAAGGTTACNTATCAGGAGCNCCTGAACGC
+
(+%&!)"$'&##)"&)&***#!(*)%+#(+(+)!&"&!""$*+%%))!(&((%#()"('()!&!*%
@r6617
CAGGATGCAGGTGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGAT
+
EFGDF-3.D:E$?B#-G+17??;<'4,3A@7<.5@$%#,8--9;2?E0=58D*%.9,.#4G"E12>
@r6618
GNAGCCGGTGGTGGCTTCANGCACTGACTGACAGACTGCTTTGATGTGCAACCGATG
+
)&*(&*+#$&%$!)$!*#*"%!&"'"##*)$+'%##!"+&$&$"$&'!!!*"$%+%$
@r6619
CCGTTCCGCNCGCTTNTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCGCGAACTGACCATAACTAC
+
2F3D'?-<)E:$F+G%&%.7A@:+5>>*2#2%"*$9+8):0"11=$3:2"55B,/&C,&0!G5C4CA%*
@r6620
GCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCC
+
H1-?9032.5#+F+01A4/*7.6>?H=C<@24!G'90!-!E!+&7F!5G#%F,#ED7//?,55'0G62/2/2,586%#67))#+$!-&,6*/4F$-/$!'25C!<8.E$&FF8EG>%5/,*+(7
@r6621
GGAACAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGNCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGC
+
$)"&#+(%!+%(+$%!&"#%#+#$'#&+!##+)$'()&&%)+&%&&$"!"("*'*%"!(+!'!($#)!+"'(!&")!#&%*++&+%""%&)'*$)(%%'+#&%*+'$&$%)+)###&+#$&)(+)$$%+'#%%*")("#$(#$#%#'"'!!&$%#&%+!))%%'*(!$(%$!)"!(#**$($*&"#(*#)*)%'!#+$!++!!)$%"**#$$!!&%'++$&+&$%*%#(
@r6622
CGGGATTTTTTANANCTGCACAACAGGTAAGAGCATTGAGTCGATAAT
+
'()'+*&*+&(#*!!%!""#"%+*#"'%+&*&"$+*"!%$$$(+!!&"
@r6623
GCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGACGCAAAATGTTTTNTGTGAAACCGCCTGCGGGCGGTNTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCANTAAGGGGCATACCCCGCGCGAAGCGAAG
+
,%:A!5'83:9A+36%>=>F*<H;#'=?.&(69<3:@';#3HH$")8/"#&*@>AF1;/C<8#4F>54+:4D665.-?3$.;07!57;95#GD%5@)<#(E%*1,;3B)5->/6A5&33&H;)+-(7"1F/G7,9F))?@9?91F3?-1?6<AA;")6F<7&*4&D.F+58(C7<20"(G7$DE180:
@r6624
TNANTCAGNAGAGGGCNCANCTNNNANGCCCNGCNTNGTGCAACACGANAATANNTNGNCTNNNACCNNCNCNCAGCNGCGTNGNNCTNTCNANNNNNGCNATNGNCNGNANNNNNCNGGNNGCTNTNNNNANCCNNCCTNANANCNNGGNNNTGCGCNNAGNCTTNNCCTNNGNGCTNCNNGCTNGNACNNNGNTNNNCNGNNNTNGTNTANNAN
+
##!"###$!"###$"#!#"!!"#"!$$"""""###!#$$$$$$"$#$$"!$!!#!"!$!$$#$##$$#"""!##$$$!$$##!##!#"!!#$#!!!"##!!#!$#"$#$"$#!!""$"""#$$$##$""!$""#$!!"$"$$#"$##$!#$!#!$!#"!##$$!###$##$$#!""!#"!$"#!$###!$"#!""!$!!$$!!#$$$!$!#$!"$#
@r6625
GCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGNGNATTAGCGACCCAT
+
.4.31&<G0")D!-2>,/9,F,5=?9+<%:1>CA8',.?8?6:HD48-CD)!8966/!490F+@,)0'F,9A:2BE
@r6626
CCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGANTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGAAGATAACCG
+
),/%;B7>2*=#,*%#A=?,-#4?-A:>FG,*<@?')3.34@%>@8;0,/?BC#&H(HB8"D%/>?6G$,-665"9E(3@@4&,E#==8+!,6'1D:D570,0@,"9F7)@'386&>(.#)ED!:5&&H8,,6#1<5"<<,-4:,-2C>7+./G9:
@r6627
CCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGT
+
:)%%.+<4$20G3'<+FG:D$8D0A:#+=H6/7F(;E3463'!(-0*9%92!8?F&B*/D?!-0=")$&AH/'8>
@r6628
GATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAA
+
40+GD<G=#;1A1+$(4"016F2F'GE@?#;'HHA-AE::'F$1$;*D,F07"<D6+'C(DFE..*(
@r6629
NGTGCTGTCCGGCNTNATCCTGCACATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCNTCACCCAGCCACCGTTACGTTGTATCTG
+
#0)/08;!F,>><!F4*HB;=@F)=-DF9A@9F:83*48&;1/%48":47&1G3.*AAF"-?FH620!"9+6!FE9=C;/F%$;4*D19+C>,+9:7>#*5)-E>-(25@-@)C&+:?<'$.=/FH3'@49>!82&D+='&>7/*B3!10
@r6630
ACGCCTTACGTCGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTG
+
76?7!$8,&(,EG:#@HG4B415>''A6=F,.C<68@.DA$4&/%3H(G:=!4=CA5F5),B?/2C
@r6631
CGTTAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATC
+
E2/C=%5,49%AG4A:'4/F$C?,@/(+$GE$((=)+75'
@r6632
CGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAA
+
+9BC<9$8C;4--,D/>@"7B>GDG'D>9"'#0$2BCD5,<3H6
@r6633
CGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCNGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGNCGTAACNGACANGAG
+
E>8%3C3A60=G!&F<#7#'FD%+G>G=="#'@E+-;A8A;7#%2>)#6=9"-.!&;E:A96A9@"#@<E&!E8>3,:5-+5&"F+BC,7*<H,#.@#1!+%;+*68B5CG(?3064C0B9,,:<>)224('<"D&9(!,
@r6634
CGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCACTTCACGCAACTGGCGCTGGGGAACTACAGGCTGANAGTCCGGNCGCTAAATGCGTGGGGGCAGCAGGGCGATCCCGCGTCGGTAT
+
D#F4$00$D!6F/%"??+$9<E4B=+6:$68:C,%1:AA$GHCG7,G$H>6907C!A87F"F7)#,65+=A)46E'3C>$,!!-<F'1$-/:90%*.E555!'=/)'09!)"3G-F<1A//*+#?3<
@r6635
AGTTATTCTCCTNGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGCCAAGAGAGTTACA
+
E$!C(==>2G4CFH8B6'&2A<B04F5-3#)5B5BD*02)3*#582G.,1>.=DG,'>.0D;+)H6*'$'(2+7!0.C'$GDB<FB)B"55?(&.$C4A
@r6636
CGGNNAACCATGCANCATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCC
+
%$)%$"#(&')(+")$+'!!&!&#&&""&*%&+#&!!#*%'"&$'#!#*$"'$!##&!"&'&!#($'%*"("&!+&*%+#'&)%
@r6637
GGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGNTGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCT
+
F;F-@9!+82?"%=,<G/,=;H@!BEFF+>)*26BA/800=<D5;C:")BH+BHHA96+.:%9F03)7"H9:'+%,H60DD(='G6B+A36)7AD)D.-&6-(96/2@2,.H+5C;".6,-+"))C($+5,&*DB5;6(+<??2((E'H2
@r6638
CGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCAGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAG
+
;0093D*?7A.A"5/C4?85(!0;43.7$E@#:?,(C49%C1A1*:44!=32/<:(&$@=2(BA<9>/1G$B@6+-2>>9B;90/G,A?!00C-8
@r6639
CTTAACAGTGCGTGACCAGGTGGGTTGGGAAAGGTGTGGGATTAGCATCGTCACAGCGCGATA
+
4C0";8EEBGH.0"9BE0<!($#,?;,7C2'*G-.>=(F,2(/?;"G#80HHC!4.%=2(;AA
@r6640
TTCCCACCCTTCTGGGGCCGGACNGCATGACANCGCTGCGCGAATATGCCGNTTATCACNNCGGTGGCAGCGCATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCC
+
+;-&/!--+'&9#352)18#;0H=-5F?*&7B+-?&5D:;+(7;3#%70>B'-(+FE/;4*8>'$/E894F2.+#;7:?.FF+EH$@C$(AF&FE-'.F'H1#??#5=%!-3B&%+=;3;8+80BD:4%EC'./C&C
@r6641
GGAGAAAGTCTTAGCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCTGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGTCTCCACCTCTGAATTTNCGCCGGGATATGTCAAGCCGAAGCACGAA
+
#,=G35$&!ED97G#)4@2F*@5F+?#);4B6?CD8=/6-C=$7"-:05)%!3--4D)/5!1;#6>H/#/8(0C&6)+6%D$%7B)2<-'=>@&1-#>?,3"&G@0,):>8>:"08'<&/C"HB/C<#!(;982B+#:5*2F,
@r6642
NGGAGACGGCNACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGA
+
#((+''!!$$"!%#(%#'&#"++$*!*)$(&&&++#)#&%+'*&'$$%)%)()&&*!%$!+%"'%($*%
@r6643
CGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATANC
+
1"*AE'>8+2*;/$(;9=-9D9-,;B70&1(+8;"E/(;%$+
@r6644
GCGCANAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGG
+
.0$3A3B=<;B9E%;+*$BH*3$+":%<:#7F0<3,7;/$E#BH>
@r6645
GGATATCCCACAGGTGAGCCGTGGAATTGAAGGTTGTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGC
+
8#63.CF?"2G%3E;HE%0%!7$?"-(,3,;*,(*%1B3EGC"D$,!0)F?BAH0,1E'"H==+6<:E8)0G0(8)7?;%F
@r6646
AATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCCGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGNCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTT
+
C!&,$/12%42(B+7>/=1(0"E)+'4"?**+<F<F:F""7><=E6#)8"<#6;F1>5BA21F.#A$5CB/3-4>)G">,B>D*$3D0<5D>;.0EF".<F'()6B2)?48E&)$7-&<2G+0*:-;FB#7D3*9GA$!!H1H3D#?5C*A5;(-5&,(%)>-<E72A?:03%9$-.<!F-E*H%:2>(0+,'C-;A(/AAGDC#:#>6=<->/'CDB/#>D()=!>>597B')F(B=@,/9)'"$
@r6647
GTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAG
+
/&!B'F>%3:"0#,:H0"(#B:*@;*=()4;)8B+H=9H-4:2(F,:9<">8@&!9)FGD'!1=7!@5,2E5&&@24.2D91=;"#DH9$:%.!37$/9EF,D*,;A<>
@r6648
GCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGC
+
-"-9&+%9;#B,%F>'8!>.,65#C'9"CB8./(1F=22+8F.
@r6649
TTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGG
+
>#$/-))=G@GE!+F)8B,1:4E=71B($@%<AF3!'%:#&"C41;+529FF13$'%-2AF+>+(-%>?58@,?
@r6650
NAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAAATGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTANTGAAATCTGC
+
##E3F+1<&#GD./?'?<52C&6-F$?(=H4+1D#G)7@)%64-!59G0'&"9BE+?-C$F%@A2++F/*9'*?H#*#<+H1C9<=6A->;=*7B.0*?(F6&$,,#@=%G$1!B<8/.H@-5H,>$@%586G9*4B"@;3,5E,3(<%23CFE*3@>2C'(23'*,+)+<,6/A%80E-'806*!
@r6651
TNACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGNGATGCGACGAATTTTCGCCGCCCCATA
+
(!685-"2A%)$'G;:C*)2*B7?9*'!34,/10)&8/FH9=)94C1+39=$*600=H/='151C'4GF5G/64">/9(E;";.D!FEE
@r6652
AAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAA
+
;C27&$E%D>0:>)8(4(F+0@(D!'4!DG60B0)B!>G29'4'6:(=.
@r6653
GCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGACGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCNTTACCAGCGGCGGCAATCCTCCGNCCTTTTCCCTGACAC
+
0"9'4%2*9A)!:;(@3<')G6='<7"#E*-E-4?4+&<9,!DE4/+'</?0F*;.?56;H&4202:@!?9:=C38A,B>6H=0#)E*)&*);6EC-+""*1?D:6:!/*49$0E2F#%*)F3<;5A?$-!E##.!<H0A=-.DB"$(FC(&(0?4"-')
@r6654
GTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCNTTAGCCTCC
+
E6,$()+A@'C;50&&"5'A9;&(@/.AB85;6&11+&A*;60?C
@r6655
ACCAAATACTGTGATGACCATTTCGGGCGAGNGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATGTGCAANTACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATC
+
8:77*:D@(/40-"C0-(@4C<HA?/:1&:>52H(!,,!F'4D'B:#(7>"0H5D'=>*HH95;*G7500;>'/<9D?>%A9F4"GG=B2!E78HF14:,G>290#=HBH"?5C$%%5)8=!(6<1%)B5+("7!22E")89%@<':;$=4/"(5?H6&;5":475G300*@F1/F);2@C64*G430*@6+.8!.4('4C?H1#1GB127/15;=.=1DA
@r6656
GAGNANTTNGTATCANTANCCTGAGCCGTCTGCAGGTTCAGTGAGTCGCCCGGCATCAGGTGCGGTACTTTT
+
(*!"*!!$"('&'*&&)(+(#)&'#%))"&$+*$)!")"++(&#*!&(#$*"%)&&&'("&%#)+)"+)!&(
@r6657
CGTTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTACCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTT
+
E#%GB4*:.77H6,CG5,A3D/6(CGE4!!*53B?44D9@*(00!@EF,%;129FF1'@&&F5630D*"CE:@+$4F8<9-&C$">#$)7$;AFH)6/+%.$9A>!D;'*G3G60C>(%<(1+5347A-=09'6*G0=?1!/4GA,9,6?
@r6658
CTCTTATTTCATCTTACATTGCANGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGNTAGTCAGACTTGCACAAA
+
/+.30@G+5.<A?!.C"9!@E#A=$+E1?%/(@*C$1!<+*F;%CF5@.%-/BG=@=)E3G%1772/&#(4H/*6"D-?HC806C7B1F2>"354B-?*-
@r6659
GTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGG
+
CG6:D)';6;@83%+F-H##-9*1%)CDB&=0?6=)3G4$6<(/9,!;4
@r6660
GAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTAT
+
>4!29*<!B!*D+B-H=>+.H+8.<@C.:7?"B028E*!2#+5=
@r6661
AAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCTGAAAAAAGACCCGACGATATGATCCTGATGCAGCTG
+
3%80*?0+6*?810,1+@-+527H@)3(7++1<#*/:@%?4#%'+70;G;!$$$3:;8702>F3$'54"G($'+G:&.&F)A)7$A;%9'/BG@&<1?*
@r6662
GGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGNCAGCAACAGGCCACCCTGCA
+
G1$G<&<D',B%B</F!@'.<-5/F11!(!98.B0=;AE&*2?F$%'1AH!!3*)
@r6663
GCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTANCCCGN
+
62D-@%D00)&%%=ECD(D"95<'!FE0,@/&+"9?9='/FG'ACHH/+6:%7@DG&EDD@'A!'!(G@>"*;30#1E7?025C-1<)<
@r6664
NAGGNTATTGNTTATGTNTANNAAGNNGACAGTCAGGGCAGCCACAGTCACTCATTGTCCNGTACAGCCGTGAGTGCCGGTGCACATGCGCANACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATNGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGCAAAACACCGTCAAAAACATTGCATTTNACTATATTGTGAGG
+
#(*"!%%)""!##'%!*#&""!&(!$"+&!')&%$!#!#$%*)("#$*&%*%%*$)$**&$&+"''#(++&)#)&(+*#')&&()(%*#!'&"'!*$'&$)(!++!!$(%(((*$&&&+'((&+#(%*'%#$(+$'%+!%&#*(+%&)#$+'#'*&$#+()&+%!&)""&%+)%"!$+"$)%"#+))'+)$*$"'(&()$"#$'$!(##')$&'%"'*&!'+*++"#$)$')()%$$**$+(*)#&
@r6665
CCCGTTTGCCGGGTCAATNAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGNTCGACTTTTTCCAGCAGC
+
FE(G+76GG**?&1'9@G#&#%8!C/AH?',H(D$47@0(GE",@!*F?'1BE4337)H<@+"/*C8<5F$0G5$>(7&4B32,/#BH+C3"B8E>1</G5FE?)./=,:A@<$D6GE&%@B+FF2&B=#-2HECF;!F?F'EE86A37?5CA>>(:/;0)85/3'3<D.A@2;>H+-$H8E*0.7D3,:<)"(&*A(:9FH*0",F<8>*/#H=7=)1!6B-&.>:(0+/@#&&1!#;D2
@r6666
AANGCAGCTGGCTGACATTTTCGGTGCGAGTATCNGTACCATTCAGAA
+
D+30,D#FH3E:3E<5+6:9H16"3:,+E/!(1&G;=/8+3GHB*E46
@r6667
CACCGAGCGTGGTGTTTACGAAGGTTTTACGTTTTCCCGTATCCCCTTTCGTTTTCATCCAGTCTTTGACAGTCTGCACCCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCT
+
;617*31H1'/161>H>*%(?:47"7$*:>@;#$>"#10G)>%&D=$A79+<A$.:!*G&23&$??H0H>$8F&-#?';-(D4B4H!8;08GC*'=1;@C((?D"?)&;HFE"=;'6$250>E,"G,?9$'6D?F.7"
@r6668
ATGCAGGGTGAAACCATTCCCGGCATTCANCGTTTTTACATCGT
+
&?>F/'-.E95&E?-;F<"=<-C+"'-"4.&E!->)<;CB5>17
@r6669
GATCCATTAATGGCTTGGGCTAAAAATTCTCACAATACGATAGNAAAACAAGGCGATTTAGAAATGTATAGCG
+
7-DAGCA,&G=B;%3%*76DH<9,G=:06A2$**<+H)5EE")B##E#$GF#@AE<8=/#&F:<:D+E8;*(4
@r6670
CAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAA
+
&&H4F&=G%H-?.C#G@1<E"?*/6"@+/B50@CA2,2C8??1.(?78!>:(=G7F5;
@r6671
TTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTNTTTTATTGGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGTCTCCCCATTCAAGAACAGCAAGCAGCATTGCGAACTTTGGAATCTAGTC
+
D5)BFC9D<'-;B?"'*1*!4432/%6D%7?CH39$$9&/(%1BGA7<3#9)1+*H'-$B6$*E@9H=C&@/;82D=AH?"8;;'B9)B5%*$?5-9-&+:4$'7"#+%0:3'417F9C*6(='D>G0;72*#:.'D+*&)7AG%3G3#'82/3&4@+C*0F:=*2>F.?28H+E(=85=($</=<=25(@7(=,)/+
@r6672
ACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGANAGTACAGAATGCGGTTTCCA
+
/11H1@)32."%9G2@E4(=;-0E&<4.-/)-?D)<E%)1*<1H/"D!@-#>+!"6!<7(#*0;>))7A$60-@3<GB
@r6673
GAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGNGGAAATATTTTTCCCCCTCCGGCGTGCTNACCACGAAGCCGCACGACTCCGCNNGCGCACATCGCCGGGC
+
+*%(+%+$*"&#(!$$"%+++('!$)"$&+)"&+"$$+&*)*$"((!($*)&+**!+!*)+''*+'**!++*+')!"$#%")!(#*+&!!#**%'!&**""(!(&$)
@r6674
GTNTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGC
+
###44@41H.C$)38D(G8#G"CC#CD;6(F:*35+.A004#,+>
@r6675
GTNGGTTTATAAGGGGAGCGGGGCCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGNCAAAAGTTAAAGACCTGACGCCCGGCGAACTNACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGAAGACTCGANT
+
1&(:9B;9@+2>*?;$4#GB+5/+4:/)/7F-@/7"1D>*5.+'FGF"F#96-<=-?'F=5(86$,)(.974CE7E!,;8F.>*'$,&A4(B"3:++.D9B&&4*39F=69D<>D!5)((C?>:7-1AF(C@4<3.$;;EF43=:'&3!@>>C
@r6676
GTTCCTTCAGGCGCTGTTCCGTGGCTTNCCGTTCTGCCTGCCGGTCAGTCAGCCCCCAGCTTTTCGCATCAATTGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCCCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCT
+
..,C3H:/@61C'=3EA*B:8DC*=4A)+H>;<(-4&,,"?"F@<%"9*#+'3/<#.A*)8E.D8!E5$7&D7>/.@.4.3"6<#F:4*F;C,$29B'%8A??3H+8+6)H7),07&)9(558&+@*9(")#)C,HBHHA"(,88H6:9H@(>?#>H;'!"0?6(+B&6C($>)9;#GFA).,/9(G3(H0-&34;@EH-2$5<59/>A-'+9G&@;2,*$*(,)(%<)@A,1*:+6-@@@6!.G"C<2=H&6(:80.#"/)>2.+-%&#1B4</FGH2*:0CH*)'22B)8)2$+:>&A(".--H#C1"@DH+#FH68@+B4"@%1?B
@r6677
TTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTT
+
D)(!%95>1,3:D-57FHH$H;!422H$=G;9B&C%%>;3,5%@38#"D.4/5*/&!E-
@r6678
TAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGAC
+
+%++!)((%+%!&)""'$$*&((%"'**"(+"+&&$%#$(#
@r6679
NGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGATTACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCNGGCGCAACATGCTCTGCTTATAGCAATTTCANGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAANTGGTCA
+
)%1!.!@E.;,D#77D(B(&2@+)BE6'=D86?ED.<862B6C5E.>#($4?C".BB:7!"7"$&*289%98C/E%#=::##@6,28;8-/:?@3B(#A2!$H!/&G"-%/@)9-*0=%5-A'$;%,,0&4>2.)/6$'C9!/*+2C2.3-;:0,9')='@#A>&.1:1<+(4@@-&,A=F-GC+3(GE()D9:H
@r6680
CTGACTGCTCACCGGATGNAATGGTGGCTGACGTTNCCATGTACCCGCGTATCGTTTCATCGGCACGGGCAATGGCANCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCAT
+
;()6!F*-2@9F/7?8:='""E,H3>=:,&*G@)/'5C=F7:4E=37=:;:EB:C<+<%?C2/?(A=H!&2+2.,FF+&#3E9(6;8D94$6$F;63+@*@$G$71<H@/-;+0/1G"C$*A=8H<
@r6681
ACGACGGNAGTGAGCGGCTGGTCAGCACGGCACGGACGACGGAAACCACATA
+
/=:-29#$A5HF,>&<=F>.$C74#6@.8,2A&$$B&##G!69A:F<0/6A/
@r6682
GTCAAAGACTGGATGAAAACGAANGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGT
+
@>%7'7>'!);&0!3G,'7H",7?HB,8F2??3276$-#"?<+E6<80"45*5*-C@?)/3E>:H999"
@r6683
GGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACG
+
H2F@CF'*H@EGC=+F8B=!-3=)=6<8#?7&$$A-%#2<D65D%F67CA!?)7#>843!.55;.79A#/=GG$9A?B:3,G$.B;>0*4!A@8E(;&">=CE2"#<3H"A"?C,#=!>(B66AG7GE%)!?-A9H(6'%,D9EE7%GA2@8G50$F4)E8#3%-B2$92)5A@5G9"7?1=0,59#?*E?<
@r6684
GTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCG
+
B%F16)&.!3@*>B3DD"'(2<@F3-!">0+A6>(#7'44/:*+<=/#(A
@r6685
AGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCA
+
4;!/2?3-2&#)&AC5G>(G$FB7C%E*DF07CEH@F1=>@-0A<*-95!94=;"?1<3A2F(!:+B@..C0B2(2//G&@'';C>7$'C=;A*':F@EG#"?;1E,3A.C:#)#8-:&8)@B
@r6686
GATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGC
+
G;.G<F@FB+F68E8H<=<7@-F@(3(>"43>#:*#9%5,A##>66?@C
@r6687
TGGGCGCATNGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACNTAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAANAATAAAGGGAAAGATAAGCGCT
+
17E:&8+#G;!2,2:?D*@D(-:2H(;83%&(=/)4!>1G1,FH(G4F41!55%H7/2)F!DE@&=6)*(2H?D'63A'1>CF*16*4.0&2G<19,86<9?$$.EB+&2EA:89AE)%3+D63!5AE:20,#@&8BDC:-"<<,.2#/"+@+
@r6688
NTANNNNNCTGTNNTGNNGNGTNNNNAGNNNCGGNCAGNTGNNCNGTNNTAANCNGTGCCNNCAGNCAC
+
!$!!##$###!!!""$$##!#"#"!!!#$"!!######!#""!"$$#"#!$#$$#!"$!!!!#"#"!!!
@r6689
CGATAATATCCGGGTAGGCGCAANCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGNGTATTTNCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGNGGAGATAAATAATAAACGAGTGGCTGTATGCACAANGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGCAGAATTTCATACGTTAGCCNCATNCCTTTCACAAAAGC
+
<.99;@3A&G(<27H27;%1H=5%:,:8E#-$-;E;'5>>#C:?C%"(9$86"%=%'8F3C*9*4@5;'0</G*A#$533EA2A87%D2"&79@E;H0?=B:C1/8=E728.2"B!?!BB5;@6),$'(70;!;#)(61-'!%"?A<%@?5<?):4)D5?C)"D*8)3?+2,E-:*"??8B@BE?0-30C!B:>E0+E=-CC$A)C5,+/"=%,?%??67.+&%-0F)E?<07!7G6C&>9H5@>'')FF)<;G54%A8E(&EF(4G=88@'E;87+@'2*):
@r6690
ANCAGTGCGTGACCAGGTGGNTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTACTCGNCANCTCTCCCCCACAGCTCTGTTTTGGCAGTATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGC
+
*'+")+$&"+%!)&%%'+'$&""%*+)'')($+"*%!$%"*%("&'"$+%+()&&"+$%$)*&&'!+("%!""++*#"&"')'!('""))+)(*$)'"+"**+$+)$#+'""#&%%)'!$*'$$!%)+&!()!(*#)*""(&&#!!%*)#*++%)*%((+$')#)%")&'&'*+)!"")%"*!'**'*#)**$+&&"%$!&'"#%*&
@r6691
TCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGNAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCC
+
)G=A/H/%#?7#H)#B<"950)33"&CF1)>4$H?7$A>G=G;##<?(;(*,2;3/<5CG)&@?G7C5<!0;H/><00,1>90C3G!+E9$C)F+:0<H'D5((GF9C$5,5/GE*A8A+=GA?:C"B@-677;:*?54+.830&&0@*"25<-?1"CD-
@r6692
TCNTCCGAANTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGATATCACGGGGCCGTGGCAGTCGCNTCCCAAACGGATGTTACGTCATAAAGCCATGATTCA
+
&)'*("("#%&+(*#")($$+$"!)*(+#!+''(!("))$+)"&)#!$"%'))+!"*%%($"""*"$+)#(%%+%"$*%++*'"%%!$)&!+%')(%$+$)"(('++#*&!&#&$'*%'"%%)##$&+***%
@r6693
GCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTCAACTTCTTTCAGACCATCGATGGCC
+
-*$8,#50#>*);9/)5G)/%?4E;8E2@(12FB*#DA6E*&=;=<G:A<E=0>>!&.>8F+4(.E7"H;:/#-792A$H$%*#%%+0?DFEH@42',@D7!B;54@"':&:>@3?"3=:#1-">H7",20C!&%81<<4.&)9FB#'(3
@r6694
TTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCNTTAACGGTGCACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGT
+
;#<">).;D1)$B/;H-4G'>,C<6&((G$5H#<<9,3FD/=5!<#G4=3@=8CE>>H53.@+F)H(3)@#,8+'-A$7;!'FD9@$7A6#?-/,'=H4@A@'+*A*#7@&=(4:CH@0@044.4+*A!0@E'$&'%A&5"8/1F9G7;?"B6=5?'4<!E!0G#B%=5@1
@r6695
AATNTGTTCTAGCGGGTNTGTTTTTATCTCGGAGNTTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGC
+
*&$!+'$&!&!)+!($$*#"("+("#!+#*%)'$*!*)&"*%""+(''())!*&#++')+%(&*#+%!!#*$#*#*#+*&&##&')&)!#)))!$*')
@r6696
GGCGTGCCNGGNTCGCGANATCTCATTGNGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCC
+
'*%')$*&'%)%$#*$"$"'$%)##('!+')$"!(*'"+%!(*!#+$'!()!'!(*+(!$*#&!)"'+!'*$'&$+(*%')(&'""%)+#*&(*'+##())"%(%%%""$'$!"!#
@r6697
GATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGNCCGGACTGTCAGCCTATAGTTNCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGNCGTCCGCTGTTACGGTCAGACGGAGCAGGAAA
+
)E+>:E&9B)-)$F-5<C!5.&-:&;-6.162B!1$'A8H*#B2C<DC:.:6F%"4"#C2'DD'F>HB!G!-EC<H;BC&:1+"C.AH:8:5@;#:A4"<1-AF428((?A:;G-C26'0!E=2+;@6/D+@(/E-&(G5G11+AG54E%(.3>38!39=0,?#'B?E&1>
@r6698
TTNTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGNGAGTCATCTGAAAGGGATTAANGTGNAGTANCGTTATGAGCTGAC
+
'*$*+%$#(!%&#%("%"+")+$&+*'!%%$(&**(&"+)&)*#*++##"%&)#"*(%!*&"&$"&(#$#$$**")$+(&(%*#!#)*)+#(*+"%*!#&+"$*"$!'&(*#*$#("('$#"'%("+)!+!$)+*!(%)$"*++!*)&(#&(($*$*$))'*"$'%#("'"!$()'!&!)"!+*%%*''
@r6699
CGCCGCCGCTGTTTTTGCGTCTGNCGCGGCAGAGGCGCTCCGTTCCGC
+
A>04A/8++@DB44#H@-BAH,3<;2H4?&("78?:;G*0/3%#5#8$
@r6700
CGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGG
+
+7FE(6G7*2-63$.1$?('921B5%F5E,!'+2G!B(,#6(-)34G#/G@,FC%00=F/(-.+,5HE9,/!)"8+/)6F>"31#D
@r6701
TGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAANTGTATGACGGGCAAAGANGCAATTATTCATTATCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATGAGGC
+
:AA>.?6("<#CBE?+?-<BB9;5-%B@D/>22B7<?)&>1G2>2@4G/:4!*+H>#4$),1@@6A7"(6?!A=*C!E&G.F0*>4+C4C!>B6'51")CC58=890#D-A)'%;=13.!4:?B>B!HG-:-7HE=G(8%<:9+>+9*,E6,8+?/0,1
@r6702
TACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGAAG
+
A*,D;>&./:9!*;=>=>2CEC=,6;#47DFC%)';!-3<"'H:;&!2$))D9.G(-*1;G0%+%?5"+$,FB+,6<75$6D
@r6703
NNCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCGGG
+
&!+$&'$&&$'$#('*$*($'%*"*"+!%"+!%!'*!!%#*%*#!&"#"$')#*%)%*$'!$%&!#&)'(#"!*"')("#&&*&%+$*!$)+$+('&'
@r6704
GTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAGCGCCTCTGCCCGTT
+
<"0-91?@5F-(1!,)H!4E(5'*E%9(H@4.HF@4=A%-22'HBC,D4<H)'7*=1HEE>80@.C;2;C522>0&:67>@-7'.=*2-C1HE#<D#*>("G9"40@9DHA<'5B,D:B952>1+(A82
@r6705
TGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCNGTCGGCGTCACAGGTTGCCCGTGATACAAAGGTANGCCGGAAACTGGTAAAGGAAA
+
?A:%)B%AC898">7>'+=3.,33<9C6+F)4G):H6E?:99?%'#$F-#!.0(7'.-A&!%G#?:05D@74(4A/F,A)&=)A+8+523F;,<'@G&E(BD=..&3
@r6706
GGTACGGATACTCGCACTGAAAATGTCAGCCAGCTGCTTTTTATTGACTT
+
6*H0'"$*+@59,39%,$)-B?>E;<,;68+:>G;-<A5%'((6?;+E6!
@r6707
ACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCNGACCAGACCAGCACTACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTATGAGGATGTGCTC
+
7?80=%7%'$DF';?D:;F<EEC%*1A98,@'1&!.A@:2!266>,E)>*.F1F>CCF'*DFHG)%+@-&=&12-,;(7G,)0-:7<A&9?0*?=27G
@r6708
CACGCCACTGAGGTATGCCACATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTNATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTG
+
)$%)+"(#%(+!!+''*+&+#&'%$"(%%"$*!%)!)!&*##!!)'(*#+''**#%+#")''#"%*!$$%"()!"%)("!*#+%'&($")($'&("(
@r6709
TGTTNGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTNGACAT
+
DH)D7#9#@@>7"6C26;FC:3/%?8&73/0:1$=H5E@B8#87
@r6710
CACAAANTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGG
+
-,3E&?$"$02(.C:F/0=>+2<$#D%6A0"-H29+"<-"<@&.73E,>5F-5.(>>58.4>09G;#B-
@r6711
TTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCAAGATTACCTGC
+
?<8#<=7+#GE+*FA<DA'>A:.E6;@04*G&'+C"61H/D%;353&H8+<*7HH
@r6712
AACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCAC
+
33::F'1%FA<011<&CG!G+==<.4$71?'-G&.HBB5-,B2A/<ED.>1!'&9=$H->F.&F>F@=;!E)244*3/(%
@r6713
GTGCCCGTCTGGCCTTCGGATTTGCTGNTATCTATGACAAGGA
+
847.9DG6;@*3?,"0&?;1?(3+8/B7+:%H>>;$."8D;;A
@r6714
NTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCNTCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTT
+
$%++"$!#%($#$)''#)*"+(+')#$(&&!+!!!$)'!+$)!""$'%+#&*)'!''(!))"%*'&'#%*#(#%%)")%&"""$%('%)('(%"#+###
@r6715
GCTNAGCAGTTCGNCGCGATACGGAACGAGATTTCCGCTCTTGTGCTGGTTNCACACCAC
+
(%+)&*$'!$$#($!$*&#)%)+%%"+""(#*!&&#%#"&()+)$&%*"$+'%""+**!+
@r6716
GTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGA
+
284?-+0E:9'"-7(9CF'5*F@'"F(&;+4?"))#,&.4>54H+'
@r6717
GCTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAG
+
+)&**%"*$'""#&%"+&"+!+%"!#$"$(*&'*%"$+%!#!)"!+**+&+(#'+#%!&
@r6718
ATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTNGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTTACAGATA
+
:@B-7-*#)D8E4C=)=+5.;38H045*.G(E5$A<4(5:)1EFD>9(2-)A/EH6C>4:-D.C*DF-AH=D2C>8,2C+5)&8;'=1>9"CH>"->:42H3#;782?/./+;;5&"7B%E93$$<)2*%=,3C<';..2''F(#E.$!E>HH3-E.,#
@r6719
ATAGACGAGGGCAAGGCGGCGTCAGCCCAGTTAANCAGANCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCAC
+
AD!G68@%F*D$5?'CC('13>9="G0C-@'8!9;4%(A?6(.$+;H;?D+$>)3.&'6!!$;F0;GDG-.02;#F'A?48-CH"$<1-?-+,A6<0=0'AD3A"A5+9<
@r6720
AATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGACCGTCTTGCGCTTGAAGCCG
+
FG?@:CG&)G)")+>.*9A:07D7C6F;#$5F@+D80*?7"H(+0=';D97,CE=',G'9)E:.!,7BEFA-@0$%0HB9#2)4B:(H.1)
@r6721
AACGGCTANGNNGCCGAGCCGGTTGAGGTGGATATGGNCCGCAGTGAGGAGAATAACATCA
+
)"#&'#$'!*$$!'&'*(+%'"'%!!$+!(+))"%$")#(*((+&"%)+"&+&)''#$%*'
@r6722
TTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCC
+
=C/);7&@9E.+2"5@H33,F-/63=-.:@2("&G=;#FC.!1/(8,8'5**->
@r6723
NGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACNACTNTTGATAAAAATCAATGGTGNGGACAATTCAAGCGATGCAATGGATGCAAGCTGTAATCGGAAT
+
!+(&+*'&$*+"!!+'%"!('(%+$##'%(&$))*+!#*!#*"!(&)&+''()!'"))(#"+'!&(&+'*!')&&)'$!"'*&()+*!&*%'#%#!#$"&&*$(***"(*#($(*$(&!%
@r6724
CGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTG
+
3GA/90:@E=-/'>-G'B1215%>&:(A?$-+C';=44;0@#D=,H<2"09E0D66%A1%7-(":566(AEH92GG?DD+933%7#"3=D4@1DC&,@!A#209A1#=@
@r6725
NNAGNTCACCGTCGAACACTTTCCCGCAGAGACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCAACACAAACT
+
""(+$%"'''#'&(%$+!)))(""&$$''*""+&%!#+''*)""(&%*%!)#(&#)*"!$*)$##%"#*)$''$)!$%%!$&!')&(++
@r6726
TTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCNCTCATCTGCTTCTGCTTTCGCCACCAACATTTCCAGCTTTTGTGAAAGGGATGCGGCTANCGTATGAAATTTTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCT
+
5:ECC?57#.+#>G#"?*6,6!?-:0>%5:A+-+6)"2=6!2'--'2?A=A;**,F67<8-+C:4-!?!)A-(3?F2)!4!EG12.3*-;3/<DBG@4**!8E'D&<D&E%&->#%>+'0-!,$21!$#1F&:7CC#'=$-7%E+#4EFH$*BC;5;;92*G:GG$*0!H+.3+"71FAG9.4$9+0<&,-&%"*9<%&FF7+/.0/977')>30C9/8**H0#%-8*(BE!D:4FDD8%+)
@r6727
AANCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGNCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCG
+
*!$;1.A!HG+9F<D=4$A@=E<1/+:A",,E<(%@&,=F1<-?AE1%5$4,9@;,%.?%(6D+,F;2)?*D954/@7B#?("7(4E53@E:&5$?EA*&E&/:G=D91
@r6728
TTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTTATAGCAAAACCCCGCTCC
+
5H75DE3,*7*="CB+<4/5E,1+/(#E85%:<";-38'*':66%G,5$=>+8?+=4<*,
@r6729
GAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATAT
+
0*(32(059#64%:!)5>H!!%*'+?14*"6>4:A3B4/:A.+HD8*!9+:D(!)1,,E)7"HF8=7H?:&584H1%C>,-(";?3
@r6730
ANGNTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATANCATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATNCCT
+
%!##*+*"!)%'+%'&&$$%#"##'*'"*#++#"#$"$)++'+&'%%)#''!)%+!%!%"(*%%%)'*'%%*#&')%%&+'%#(%&'#()%*#%$)'"%&##*(++"''&&$%+#"'%%%")%%"(!)#&%*''+"'*'"!&%%"&&%))((%+*(!&%++%'*)+##%&#&$"+(+"#&'
@r6731
CATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAA
+
?-!)8(*0F4'48B==E<!CD&$':H!H2:6?G?>E*./(.*81"
@r6732
GCAAAACGGCGTCAAAAAGAACTTCGTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGTCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAANGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTC
+
,-C"#("4&E)(-D$9)3>6.0A=-,D*5/G%-.EDE@!52A8"0:8HG#D92)*+/>30+*&'?!,!?/,.4%;697E0A,BF=.#?C6889*?D7284'?:H2F<-(C6:>CA*+F%H#0?F4*)EGD"5;1?&$@2)'H(54B+0,3-F#H++2D,/="8B-<<./)1088@/<@*.?@&?A7,D54#F?
@r6733
TGTTNCCNTNGCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTANTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGATATAGCTGTGAAAATATCGCCCGCGAAATGCCGGG
+
(!)%!&%!'%%++"%""''&('!%!&#*(("!*&"*%$'$+$(+*(%&$$"(*%*&&%$#)"#+&%%'$#'*&%"+*+''$#()*%#('!"$%&"+!&!$#!(*+"!(*!&'!$&(%)()""$"&!!"*$"+&$+'*'+)$$#('&$"(*)!$*')!'+$
@r6734
NCTGCGCGCCTGTGCACTCTNTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCAT
+
%@#"*BG5-EH-&+@!F#%4&<C@G@&23:.25!=%E=8#+/(/=)5A*D.;./86AC897!B)9D#A-@E39+3"-F3,1F*>H.,FE9(/31(E9@=@#>0;5F'A0/B6=>A&*)-22'=279C-$G:;2G1
@r6735
AAGGTCGTTTTCTGGCTGGTCAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATC
+
>.?10/?$.*@!%.0++#!#?*=;.*%5%67AC==G+83?D;5B?&CE"G9GE#3F&
@r6736
CGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGCTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGNTGACCAGCCGGTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAA
+
<F6E,7#EF"*4B:D(2)9%B4#G..-F0(0#6+92(#!,A2/0!3#3*1,<H'-@766%-"D2>6-/!?!2,+303#5+:?#@1B')$4*5<B:/,*,>''70E&<G-CAG"D#.-?@A.<+A4GD#()<!:2HD##,8*.0%#0*%%8AA!/:=-1!B=:=:)"D)3953#(;"H/78!H%>$5=,#"
@r6737
TTTGCGGTCGTGGAACCCACCCAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGATGATCTGGTACGCAATAACGGCTATGCCGNCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTCCCGGCTCAGTCATCGCCCAAGCTGGNGCTATCTGGGCATCGGGGACGAA
+
-=&$>H9<G(>%4+4);!=!@65<DC/>H;A!8%F3G>:G/D#8""=@567)2-#AA4C'+"DCFB66957(+?D.')0=/!*<<5-GE*1B?687".DE92GC'<6H(/!".50*A9!&:@7DC3"E/,6$)5A!0C"0+%G"@5'7=B0('F82@.F&;1":0>9'6#FD<ABD%4/B4EAA,*771%'62/!13*!@$7!3G
@r6738
NTTCNTGATGNNCNGCTGGATATGCACTTTTNCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGG
+
!#)#"*)(##'#)&++(+$(#$'#))("(#)#*!(((")!'''+$''#&!)*%#!#(*&&$*+(("$+###*%!$#
@r6739
GCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACNATT
+
B%%30>:&(.E/(G+')&'0"&&%'2@7!CG390&(+5A!6*H:A'1)&=-G@78B7?%#5
@r6740
NNGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACT
+
('=2%1+/F-)H+A+?7#-C&>48>(+A09+2H=*07.*%&8:*$B4"6!BH8F&FC$A>8@%6>E/%3E.2F>;:<
@r6741
NANNCAGATGCCGGGTTACCTTCAGCCAGCGGTGCCGGTGC
+
"$%&+#+&&'%*#!+*$))#&$$!!#+'*$*)*+&*%%##*
@r6742
AGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGAC
+
@=&3$'#CF@BA'))"G6=?*1-5?$$?0,;($2/0<(7E4,!%4#H;E(%?H)'4:/2;!@*
@r6743
CGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGC
+
0CD',/;99(E32(>E<15&E"F#+,&4-2;FD+B9,'(8B&-%C#8B%)/"&<:A+:*<576C=:5'>=+-!F017D*
@r6744
GNCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTACNTAAACAT
+
(%.G,B0<+B@>H'%0?$<.42*EE'+5/B+7(!6+3B,2:911?9:@0@H=;C;*56#8F5>G80=7*+C:/25/F
@r6745
NTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTC
+
%80G'>4A,A:)5?30+)5,&3D8E>=&+A9A*A*#)-,>*B%).8(#&
@r6746
ACCNTTNGANTNNNGAANNNNNGCAAGATNNGTCNTGANNCNNGNCANCNAACCCTNNANNNTAATGTNTAGGNNAAGNAACTNTGANANNANNN
+
###"!""$###$!#""$$!$!!$####"#""!"!!"#!$!##$$#$#!#""$"##$!"##"#!!""$$!"#"#$$"##!"""!####!$###!!#
@r6747
TGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATNAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGA
+
#B7&8%/H*<=C)&;!38DH#9A#:H=+;:(;GE6#'+.;:4@H(%;3&($/%/(C")9/>@&(!-+(2;@1+;2E$E;%+F;:27?.0?3%$HB7GA+D<5!"FGDB7;<,93.?E8@B-E?>862<#'
@r6748
TGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCG
+
(>2F.9;$72:$C;(97H2&#"CD@5D<F9",@8H,4E,E:537,.'4!
@r6749
TGGCTTGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAAC
+
F/>#,7H/+7:A*5<8;4E."FB"C)5.B6$$55-G/C-!6
@r6750
TGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCGGG
+
B'C..0F4"(EDF?&9D@F.#-728>=24%(6&9D+A8$'9<$(E/$3#G<002
@r6751
NCCCGTTCTGCGAGGCGGTGGCANGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATNGAGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAAGCCAGCGAGGCAGATCTCCAGCCAGGAACNATTGAGTACGAA
+
$%)+&#""+*!"")('&#"&)+'!%+*#+$&#"&)'$#+%'#&!%)"#+$&((''!'+"&%(%($&%!)$($&)%"+($+!"+))&(+((&#'+'"*")"*$&*$%%%)&!*#+!)*'&!!%*!(!!&)()"*)*)&'#&$**&$$!!"#$!)"+$!)'!'$#'%'#*%(+!#&!
@r6752
CCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCA
+
DH4B55.?8!2/H*<5A2%<G24)*?:!?2A8"%2,>:(BE#E-3$)?D5'?D:ED,:GBH*@+>FB%#.A*68C
@r6753
CTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATG
+
-C<3E$)81FEG.3A*3)F5E$G93C++FH(*H,=H8&=;16"$)!G7,133A,/F78"E#.(H+9'664>$'6:?#9;8:3:'+2F>)31/H*C79*0)7!!,:<9;*G8+3<6!&D6,H6*83#/7!)+
@r6754
CTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTG
+
?D94#9A)"41(%F"=&2BH20(D#>4D-G=86'6:(D)+).+>8H.':/*'#A-5B;#*B0?GH.G?$(>)"C
@r6755
NGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACAC
+
!@?E*1!)5C$.0+9D&1A/*B">6%0:*&:),.2%AC9?>"@E2-
@r6756
CAGCTGAGTCCTATGACGACAGCCANCTCGATGATGAAGATG
+
')?)%2(AH:8E*='<"D<F6#*-?*9B7A/E@D)4*/G/,#
@r6757
TGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAAT
+
8HA'!EB)?'D/6#7*9'H+D*)F!C$:2&@5.+&&'-9,<8D6@>CB!>:+87FA$5>;C+$.@(>65G@&/;##24'E&3D?-A
@r6758
TGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATG
+
.)+F:=&1<!<'B!.'-H7.>/%8=.)-$=:3@5968C%@BD?(/(FAH<):;@5"<F#<#7HE4@70+>.6F>
@r6759
TGGNTGANATNNCCGNTGCGAGTATCCGTACCATTCAGACCTGGCAGGAACAGGGGATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATTAGGTGCTTTATGACTCTGCCGCCGTCA
+
'&"!(!#!''$#!*)"+!()!%+!**#*)"'#!+"$*&$)+&!*+*''!++#!#*$%"&&(&&'!$!#%!*$#)*&&+!%!%#!&!))$%&*!&'#*$%'$!&%!(&*%$'#"+"&!
@r6760
NGNNACNNAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATN
+
%*"%*)!('&!)+#))!"$$!&&$!!'+%+'!%"%"$*")'*()"!+)&$)'%$+(%")"+$+!$!#+#&)!++%'*+%$&)$'$!!)(#"''%"*)(($#$"(*"*$!)*!'''"$)$'*)'"(++&$+&%&#(%+%*'&&%!
@r6761
GCAGGACAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCA
+
**@9H;HF(&2,&A(!/*,2,>597A$.$'.G/G!DG9,+(91=;C)
@r6762
CGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAACTCGCNCACCCACAGTGCCAGTGCATC
+
6C"9!'G2A'62+$@90$$44H@,0;D2(C<@C6-E*)>!GBBF59B".>4E#<*C0@/$29<*6;
@r6763
ACGNTATTGTAGGCGGAGAGCTAGTTACTGATTACTCCGATCACCCTCGCAAACGTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAACGACTTCTCTCCGAAAAGTCAGGANGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATG
+
()#%&&&'((+%*(("(%$+(%+%(&#)"&#'#&"!+&$)"!+&!!#*)&&'&((%#!$*!#$'(*)!)((##!'+"#*&)*)("+#!")($&*%"#(++#'()%%$)%'#'%*)&'(#(!()%$'%*&(+#$&'##'&+&&%*#'!+**$#$%%$"$%#'*)((!*+)%#%(%+&+!%#*$&*"")"!")%*)$"!"&#!"!&"'+*#""#!)!&"""&"
@r6764
GGTCCGGGAATTTCTNAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGA
+
08E%?&+-@FF.69+H2):@$"F+6$H;;;/G74<=9CG@F</=-!?:?;<"65?$C@
@r6765
CCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGA
+
/8/8#6!FEAG9B8A1B'=HC5((8=2*H$#!*2*#CAB972CC8>>:AG#&1".AGA.;C%;
@r6766
CTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACG
+
E5&D9589(4(2D,*0=.A>5E*&'"/@CA%""?,A3&29>'=GA(!%)6$&31->2=DD;.@&>;((.5
@r6767
TTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATNCGGCGTCGGTAT
+
;1,+8+$?#)./5=@>#(#*D6%(+#A2-%1(9'160"?$D<C#%D$2;?!.;-(+@->#7">3.@/D$0$(@E?,84-1!E0%4
@r6768
GCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTG
+
423D5?'1(.B7!4-0A!6$@=0A14+H8D8(-$),7"8755E
@r6769
AAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTC
+
'?<=9=(+.@-A:!&!A%A%B,<@DC3G/F:2)%?:D!%A0,5*<).!B"9;&FF!$?G>!=2*G,H<5='.6.$,D4:('"D.%.,7:<9D*.!)FG/H;1EG>487F8>*#7HE65:
@r6770
TCGTATTGTAGTTTTCTATATTTAGCTTTCTGCTTCCTTTTGGATAACC
+
#F2,$HA/,H1>9<''A=&HF1+4;EH8?7#(>1H;3B-6=,5.=2@C0
@r6771
CGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGA
+
36510%?#!3F)89@D'8GE$?HE5>6?F68:1-#CDFEH#A1'H86G:*98(7.809?04,9245+*=,/A"9,A13'%6>=3=?%A9+
@r6772
TGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCATCGGAAC
+
;5<4<)60C7-C6'4,768@*&.@:=4<")A*B-<(('@5D@$%G$$A$F6/$B7),(,'G#)0)+)--2;B/96"GD'
@r6773
CGCAGGAGGAGTCCGGTATNGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGTATGCGGCCAGATTTGACGAGCAGATNGNCNGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCANTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCANGTGAAGGACTTCTTCGGCGGGATGATCCCCATG
+
7(*;,5H;:=6'F6+$$:&H,2;:.&;>,>B=.+D$:3+/@.FC)&7HE<;9D@!8#4/80*=$#/A-><#-2@1E$:-"'E7),F&4*+*<%G**%?1$+*@+@E)$/4>F&/)>/"54F$AD,)&=$"D171588B%?+0@@F(F?#5>#A8D;?6*7@H2,176@/G8DA9@&,52-#-!')D8+&(=:H.)EF8"$D9#GE)1&.#9(+((>?7H*%#=H;GFF743=!6@<$),F-H&8.+199$49'C#BE@5!-?@2,.D0)-@F#,"/BC)1D>70!7/C-0H."!/H0+#,E&62(-0/>00@D(3%./GC(#?7($G8.,+9>FH%6HH9/8$!11(
@r6774
NGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTA
+
%=046B;'DA&8B7C<.',G4E,,$A#/H=H3E@4&3"#-+F8G1.#(7BBH8+;)#0!4+B%"(G-':*HE31@D7//BF'3F6(;8,EH8GF+<B9"+)H:)3.8+!F)-F88.%9%53=A:3:A6!;*B8E7F==%,D8.<?75+-+4H'6=.A#B7+%>8-DHG&"A#1<D1>=!=#=")$67/G%''?=-;(&$*$-;A>/"@#'&6/DA,#1+=4('&'-
@r6775
AGAGATTTCTCTTCTGTAAGGTTTTGAANTACTGATCGCACTTTATCGTTTTGCATCTTAATNCGT
+
:BB2%'&:/3G*+."809?E:02;-<8214%0H5;/*;/.?7DC4%24A:>'D+2ACAH&3&BF&?
@r6776
CGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCACGATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCNGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGG
+
1FHF4>>:,>H'!7.8?,&5*G5D6=@:35!:;@)FE#6G/89&/&B;*B#-?7<B:.084F*-'<'($EG&8;FH2A1E6@0/&8!$>8C:<*+":HE3<F@1G50$E*,#:)0,)EC".*>#=79+'8:7"!,"'$'A()4953,D86*/?D5(G)3*8):;A=?#<6'"(%3#+/&87A&%7%4
@r6777
CCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTNTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCATG
+
=*6F:$='-#)82$/"@97"+0>=GC/8+)',H(">!;36$5"E4B9.,"5>:4-F519:H>C*HB#-(.%("GF>.4;F+-;#12H7>$)";);-'0-#)0AD06C:>(+=;6B.8!D>$,BHB"1.1A#AF
@r6778
TTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATT
+
9.G(&5/H<A3:B@F>46+95C$7(';%"FH5B9F3=&.@C2AE:23HG#B27(8$$EA6?89*)>+(B6;HGE8#D)/$.3#'93?7!:!72(BB)$F;!AF)E/HBC(;/HGD8;0=62'=H+F$2
@r6779
GTNAGCTCNGGAAGCGTCCTCCGGCGCAGAAGCGNCATCAGCAAAGGCCAC
+
)(#+%'#)**+!(##*$'&+&*$"*!%%#*+#&'!!#'#""&#*+)'')&$
@r6780
GCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCT
+
>F,@>D!0,,'-!7,@2H?-':(!?G6A$#@/7D";?-E28&B51(=<>5(5C#'>(FC0
@r6781
AACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGA
+
8$@8H51#+A<#(G!$G'92!>7*4*#1<++,9$D:&&G9%51:7$*G>#(@"8#
@r6782
GGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCANCATTCCCACCCTTCTGGGGCCGGANGGCATGACATCGCT
+
)&)+)+%!$#+)!'%*()'&!+%'!&(!&($*!#"*)((+!')*")%'*($*'%"&$&'(!!&)+))**+($(%%%!$!%)&%+*%$$*%+($$
@r6783
CGTATTCCAGATTGTCCTGGGGGCTGCCGCCATNGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCGGCCATTGGGGCCGGTGGTATGACCGGCAT
+
B0=:$0+G4DC@4,:40:CHE*==.EE7;$A/C'6;H!<A8F7C)-*4&<035DE2592,G=*-A3?4&0D&.<:+B$'2:0F.G)G39A&6%/GBBC-E(.,(%!;-/+D
@r6784
CANCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCA
+
7E7+A>C,2C=5D7BED(%8#-+;9%?-*@.98#.4EBC2"79F@.&
@r6785
GACTTGTTCAATGNCACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCC
+
,3EH$%;(>/@'7'$64@8+%56&@E("'1/=)'(+!0)40#3D9>0@H+
@r6786
NTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCCGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGNTATATCTGCCACTCATTGTTGTGAGTGTGGC
+
!-.4()=.:>"#$9C"$?.F!.BA1BB&%(!-8=D*E7HC4:04<(#:40<A)5"4B.8?6C":719&2D:=/H5DF?-2.2/=#,&?1?0@).!D+!,+?8<$<2G-?%8707>9F"?/.7#(#E'+6B%902,C2;2-8+9$
@r6787
CCNCNGACANCTTTGCGCNGGCNTNTTTCGGCTTTTTCAGCGTCGCTTNATAATCCTTTTTCGCCGCCGCCATCAGCGT
+
'&"'")**(%*%&""*&'"&)!#$!+!%*%!%"'())#"%(&$)'!$&*!+%$'%&%)!&'#**#&"&$#'(#+()&)!
@r6788
CCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACG
+
,-1B%B3"EB,$;4)H/3A-9E"*@'@D55577,H<H'<.5<+
@r6789
CGAGGCTGGACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACNACATCGTCGTT
+
H8#=2@('-:=2/(?8)';,9/*0.%3.1E+$DDG,%)>@+>EC20F'(<#>:C&:?57?-#:&$B($>EB"F2=@@#!#D)1?H/HDG8-;!9EEG)BE">7E7>G8+.!<60="?-,0&*6F(!48C9(4++
@r6790
NNAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGA
+
!"+'%""**&*%%!""#)(+'(!'$(!!(+!$''((%)+)&%&#)$
@r6791
GGCTGTTTTTANAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGNGGCATGCACCGAGAAGGACGCTTGTAATGTCCGCTCNGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGT
+
,0/C"184;*'H47F19A-,C""G082'7>2+G7,G&3$+73&$D8&""&/?#=0#8G4:@;A98)>E?'B2:B#+!=(&D,7%/#%HF9<58)$H32,/AB9.A/&7<$0G##:9E3>B/+:!G#63+A@"7ABG+
@r6792
AAGTATGTGGTTACATCAAAACAANTCCCATACATAAGTG
+
2C(*B)5C5<(G"?-D:&4!!E58FC8D#!=;/CH'$(D4
@r6793
GCTGATCCCACNTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGT
+
E?D33<</(B%9G*&25"+G>&301$BA,6B*DC;=7D#8/9E#:&2+"8,"4"$+E%*<%EH#<&3%H$,
@r6794
CCGTGATTTCTCTGCCNTCGCGTATTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGANTACGGTCCTTGCGGTNAATCCGGCATGTACAGGATTCATTGTCCTACTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCAACCACCGGAACGATGCCCTTCTGCTTACCAGG
+
''05-'+>5@@40'1%G5#:)@%DH4<-'3-<196$:-9&-&D:)A+-"$E833!4;1F:(=$0.D.H,=1+H*EG=;65F66"?$3%F<%=)8H=6&6G'2%0H9(@2-&!5@/+B;(4'@'4#ECGB>7>47@2%!"66@#$GG,C+;%4+E:%D5%#!6/C<C<4HE979%=57D#&4CB5>#4%6-"D"3DD?B)F"-7!2/(H==B"58H<>:A':.B
@r6795
ACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCNCAGAAGGGCTTCGCCATGTACCGAGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGNCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTNAAATCACG
+
>B7&5:?;#!)=;-(%?G*=,A,;D>G2&,.<CC6!!*G23)2/8G'>53?8677AB:@*7<>CB.DCB3>*D>&H)FE)52=A$A?2-:!==3#%;@!H/'741:><;&>7*E,7G$+E.A&7!*<;?0;?A,@!'!2FG*A$HB383(<B$#!4,D/+=4C7.,;*)B*42CH<?*9.A=-"*0'=)B'?H(7$>8?*AH';@:-D7BCBC2E:$$E8602>,&7>E-A>(4?%H'&$1:069;7(,$=*6D13$/97F%!<A&#E#:=
@r6796
CCGGNGTCAGCTCAATCCTCGACGGGGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCAGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTTTGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCNCTCACTGNCGTCGTCNGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTG
+
+$))*(#%)$($*!*+$("''&(&#*#'%*'+'(%$!&(!()##$%#!#'&!)"*$+'%)$(&*(*#"!*'+#%%(%!*%$%&!#+(!!('&')&#%"&&**$%$)&$&"'+'!$*+($*&*&(+&+&"'!+)+"(%"'+'%(#%*#+)+$*%")+!&#(&!#('#+'%+&+#')+#(#%"(!*%&&'%'(')$"$$+#$"((+*#'("$"+('%%"(""'%%*)$%)&"%'#+(&*%)%!!!(*%"*+#)#$"(&$%$&$!('%%("%$''$(*"%%**+*"$##+$'&#*#*(%*(")%)*&'%&
@r6797
GAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTACCTGTGG
+
9;38A"1?#=<*E'@26"7@D@4A6E":H470&*/)&#<,0A!-*G8*G1A&!)-@F,7@#8+;1/9*G@B'A0*C1"?<&1.&1>>+:$=&HBC@G7CA*>@;06(,C7A?E866F=>.5<,<:6@!"8099,:@;@8?.$%>+=#"@,4*'B%;2A37%)7H&>-G8E0D%&(+
@r6798
AGNATNAANNANANTGTTCTTACNTTNTNNNNGAANGNNTTCTNANTNNAGCGAANNNATTCACGG
+
*(")(&()%#"$"&*'%(*&%!$!!###%)!!"*"!#%&%&(*&%$""!(#)$$$#'!+!'*+%%"
@r6799
TNCANNTNAANTAATACGATACCTGCGTCATAATTGATAATTTGACGTGGTTTGATCGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGAC
+
*!'("$!$)#!++!(*("%)+%*$'*(()$)$&"#*#%+%$**#'*$%#'%('*()$((%#%)*($%$$((+(*$!%'$'*!(#&"))'+#(#%##$"'&&'""!"'%*(#%(""+**&&!)()'+*&+)%(*&!#(#&#%
@r6800
TTCACNCCATCCGCGATGAACCATGAGAACGTNGTTGACGATGGNGTGCATTTTCCCGTNTTTATCATCAACGTATTTTCTGAC
+
(#+$#)#!+&'%#!)'+&%(())$!$!()"%+(!*'#!'&%##*!&"")*&)+&%&&))(*&$)$#)(!*+&'%('#)$#!#%'
@r6801
CACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTG
+
/3D62E'427@D7C0H*7?:%+(*E==-=A/#159=&/#B(>(9F:;3<=4E1'B7!<
@r6802
GGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCA
+
@'&5+:-9!0B?22=.G93>HF$!(/'-"9=8?;C&+&67C=1,@$%4
@r6803
GAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAAC
+
$+)!%$(")!!)&#%%(#($#%"$%+&+&''!#"!+&*')#*'++")"$%&!(&(%&&$%$)'#"&$'"%!!
@r6804
AAAGGTCCATGCAGCAGCAGTCATCCTCGACAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGG
+
!'%!$%&$*++#+""&'*$+"#$'"(('"("&$'#$*"**(!!+('+%!'*%$&"!*$($#!#('%&#%(!"$'&$*('%%#&+*#+#(&*!)$!(&)"("!'%#*$'$$&&"+"**"&%'$!"!$&+)"!$&+%)"$%"+!!''!&++%#%*"%&+"*+#"%+*)"%&&)!'+
@r6805
TGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATAGCGGTAATTCTTATTCCTTCGCTA
+
+)+#+"(+'#(#&#'"#&"&"*#%$%%("+#%!%"!+%$&)'*)+&+$')"$%#'&#%#*+*(&!+(#&&(#+$"&%"&+%$'#'$!&$")(#+')')((!('!&((*&$#*(%$+!!#+**!'#!#&(&+%()"#%&))'$%&+(#
@r6806
TNCACTATACAGCCAAGCGTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTAAGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATGTATTTTTTGCGTTATGCAGCT
+
($!&")$&#%%&*''"+'*"&!&)!+"+('!(+'!+("!(#(!(#'(%$!"''&#!&$)#'$&!'!)$("(+&&!"+!'(!#'&+)+&('*+%#()'')"&%)""("(&%*%!(+%+*"$((*("!*'"++$'*&*%'&$$(!)!**&&+#)#')#!
@r6807
NNTNNCGNNNCAANNGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGNCACGCTGCAGAACNCGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGNAGTCAGCGATGGATTTTATTCTGGGCGCGAACANTCAGGAGNAGCGGGAAAGGCTGACCGGCTGGATTGGTG
+
$!#$!((!)$(#*#%**'&((+!!+*($*'('#&*"%!$''&')++#&))&(%'$*)%&+)(##&!!*$#*+'%+"$'&(*#&$'()!"((#+!)'$$+(*!+#+$&"')!(#*!&$+%()&)&##"$'"(!(!&$%$(%##%)*+#+"($*####!&&!"*%("%'#*#"+(#))'*#%*"%'(++#(!#%+*($!%!)((#"&
@r6808
TCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCC
+
=">%4DG>)4B8&D9>53FCF?>!CH1".A,%:(%;BF>B<<%.&:?15>62'+!/E,>6EA&%7H+#$@F*56D;"G$$&6@.9F6+H4*6AA6'(F%4E.-A?37+&EF1#/'2(5%?
@r6809
GTGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACT
+
*)@"'%.'G3%A27"A%6$(;9!D=%8H$'%-/G;F#G/7F'>B-'2!;#9?*073'%9;4%7<:%F$()/H#1@8.-G!!A00C-(<:<?*FD)?8/?:98C$<C@,?"'#*HG<3!<G/1G,#BH%;>.5<(C,1B#<$,;G:?)*$D9.&,35$.BE@3G4'H>'G2B"D/H>5*/
@r6810
NTTTANAANGGCNTGGCGAACNAGGCGGTACAGGTGTTCTCCCGTANTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGT
+
!)))%"!&**%'("')%*%"()+'*(($#"(*+"!'(+&$!&!"+"&)'(!('()*+*#+%(#+&#))+!$$#+%+$("%"%%$)**!&$"&+!(+##&(")(****)(&")''""')+#!'+!"&$'&)
@r6811
TGNGGCGGAATATATNCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGNGC
+
#()-A%4>)6'5HBA0D.,BA$9%%=B(0C@*%#F6B.62D"H)@A><CH32(A);81)(-20&A?BBA>+6D+#$0&@;'?,?""%>3BD6$*%@-854!!."8F/A-"<)H-&9<6G6/#.G,*+1$72=6*4C./-E;:+,&/'3G:%&B-7BA6<:&#-88,09&0,16B!C#AD)'-$?-=#'A1EFE+$+96&E++A/7(#)B<;-0BAA/
@r6812
CGCTTTGCCCAGGTCTTTCACCGCGGTCTCCAGCTCGNAATAAGAA
+
?.,C3)>$F",:09,*>!8/7H8E*%A<?8&D)!B;#.'6;22(D?
@r6813
TTTAACATNGTCTACTTGNAACNCTGNGTCAATATGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATNCTAAGCGGAGATCGC
+
)%"'")$$"$(%!)%*'*!%")##()$*%*(&&)!)++)!("++&(*"#&"$$#!"%)($'%+&+%("!%(#(&&'(+*%%"$!$&%++'$!&!+#"$)+*($''$)++(*#(!"'!(+($$%&*!+)(%$"'#$$%&')($(($(())$)"%"#(%+!**'(!"&(&+('%"*$''*)*"*%+%$"'&!'&#&
@r6814
NNACNGNNGNNGTANAGNCCTNNNCNNNNNNTTNNTAANGCNTNTNNNCNNANNGNTAGGTNCTNGNNN
+
#!"$"#"!$!"!"##$!""!##!!!!!!"$$$!"!$$#"""!$#$#!!$#"!$!"#"!"$"$###$!!!
@r6815
GAAGAGTGACAGCAGAGCTCCGTAATCGCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATNCGC
+
E,+?+1B*,+5.'=H$/%)@B6)+=GG*?5.-+%=A8BGA03'C)H+8(<5H1@8;0E;@3:8@$2.917;)G<!AE1/E9'4&>>)
@r6816
ATAGNCAATTANCATGATACAATATGACGATAAAATAATTCCTNAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGANAG
+
'&%%)#)"+!)!+$()!!#)+(*&"$##()%$)&'!&#"!)+"&"&'"(+&'%)(#*+'%*$$"&%')(%+'%('(#"*$)&)!%&$''$)*'(&'))%#+
@r6817
TGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGTACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGC
+
7',#4$$E)(F(8,?@#?7#B.3/60-'/693AA+(E@4;46CF;AE,<G2)#")6064,&@7>1%*(,);1'#C+&'0=(#D<7%+<17;4A'C5/(A#3)?)192:H"$C&BC1D0=,+#%
@r6818
AAGAGGGACTGGATTCCAAAGTTCTCAATGCTGNTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGNCATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAANCGCCCGGCGGCAACCGAGCGTTCTGAACAANTCCA
+
5(:AACH"1G"5CF,95A&D1-@(0%:@!$!+D''>E3D+-5D0$H<1)7'H*))6''8A9C(/><AB0H2:DG;&5*-2$/#$5+6,.@75<9<@+6*>F2C='A/;E"4"1=D?7$+%4>#EEC;0,<<+F,4,:EB*>C:B+9/E,C9>
@r6819
TGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTG
+
!77%/.1D,>51+5'50E5-G?C@!&%A-F2@2>=*$"E807F+0
@r6820
GTGTGGGTCAGTGGTATGGCCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGANTGCAG
+
:&210<$.%@8B1;1320C(GE62:+H;<9(@D?&2%8H%.D87D:),=;5B8-)G=<E$90):(#32.2!/FB<#=&#2,+>E"FAFFG-A401*A$)&
@r6821
TCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGNCGCTGGTCCACAGCCACCCCGGTGGTCTNCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTG
+
A><*)%8<C5*2F,%E&.3?A-:51@8%<7BB5+4'+$+!63F0DD6-*8?0&<*#5//0,"74@-%C-&9G0%G&.#FH(:A=>0DG"H"H&F/4CD'-D(&F)7;'A5:#D6;-128$'&H4B@('"($;4D&/8-&*66$<?'C*<7$>"'<63@+56!:):.''8#F>73A%7.''$-$35<B>:4%0,@D33
@r6822
AAGAAAAATGAACTTGGCNTATCCCAGGAATCTGTCGCAGNNAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGG
+
0!'(DH3=#-"4=&GD,?EF-/G6-'!*7,@EG%)%)19;"=67(B,H,0BC*?;%"5(318<:&@BH91@-@0+7+.<F75GA/A
@r6823
CACTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCNGAGGATT
+
('#G*C.!4B+*=?87B'".A&GC$:4/@%!961&%6"4#+H/<E
@r6824
AATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCT
+
F%3@7,D(A=-<8('8D/&800=0$=/GB1*(-7=6C(,:.E0
@r6825
AACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTA
+
>,D)F2@<92G(-H%<G2<F$//=$5D9B"&81?!#CH-3:,<"9$5*+B-+-/;H(")'84-3=;*H$$?A,501BHHE86@*EAAC=.%82/*E<(#;??!22!!51G5&1$:0'#*/#,E4D!A/'*%5G!FC=7.%06HC;@;)+.$'7
@r6826
GNNGATAATNGCNNTNNTCNTAANNAANCGTAGNAGGNCTTTTTAGGGAGAGGGAAGTCATGAAAAAA
+
%"$$&&&'%""!!"**!)"!(('('%$'#*#"*!+!$")&(#('')$(*&(+$+"+(&++%)"("+$+
@r6827
GCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTNCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCGAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTT
+
87#4%0:<H8G,H4-<86&5>#4@3!A;6A-'7H!5>5*?6AA?,!836!0::)E8;>522EE:/>/<(&G=@9;(E925C,)@!?.:+<H%&.-B#H@H*H=/1*>D>4>)@E)/F%$"#;#%B""B$.@';CC'A>::6AH(>!7H--,6!>FC710(FA+<@01:)A2?D.H4#7CD(G0&3?(H;#%AED36?F>D=CA#E@(<!8<#H=
@r6828
ACAGTATTATGTAGTCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCANTGCTTATCAAATTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTC
+
B@#:H87'A8=/872-@4'5()#>8E/,=.46C9-+8A$E-51*(*/)'"0G>B3+EB'0?"$57G?EDF/C11*BDD&!D#8784#?5#D=A/#<:C5&-$0C;C4E(=F*AB9H#.H7C+*0'2A>/++GED46@C3""/AHF>=4HA'"5"!##@(,&<:++9#79+0E*.4B2>)91($3'/(;
@r6829
GGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGA
+
&)+D&=A;&37?7)@@/<%+0+=1@)9&7.-89%+.!9;1$75B-303!$?F#%?<>HD:4!%)"('H>D2B?#3<A.;'#260
@r6830
CGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCNGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGNAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCNTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTG
+
?$7?;B1EA-B-1'(F"BD'?>B:6.92D$+"1",)4=/9%<%'H$D44"#3!C'DD5$$G,.+BG#BD%3$55?,9!78A%9D)H?=**7!,%'*>9BE"0$5%+5/1#:6"C*B$/)90-F!17@5:8;D6:@F(4)>*-<)8>?;5D+:2E2>D7A0/4*.4'!'!11C:2G*BGA$9&0,F07)>(2963$+A:7118G>G$,'>9;$(&C5.71A,%7E7&$*DE>&H.BE)#
@r6831
GGCGTCCGCTGTCTGTTCAGGGGCATTATTCACTACAAACTCAAACA
+
+(H"5#+&F,@+4)G8*:0506/72)&509?'8?@C@(H"1#@)422
@r6832
ATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGNAAGATTTGTGTAGNGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACT
+
+**&(###)+#""%%%!&)#&(+#$*!!'$"$)(($('!%$%!"%(('&%'&&!(**+)#*(!""($&%$'&$!")#!&"+("%((!&'!'!&!+#*###(!$$$'#(#$*&!")'"$!+(+*!*$")!(!'%!*''(%!("+&*"%$(#('!&*")$#%"%+)+*+)!
@r6833
CGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACA
+
9&D$$&4#<,90E'%C-<@*,G><63<E02();6C*-'4G%G@.,6>A-.3=46<$+#21;#0FFG!!@"%F=$2!B:.":073/1
@r6834
GGACTANCTNNNGCNGACGGTAATTTCTGCAACCGCAGCAAACTCANCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGT
+
'&%#)#&$)"!%$"!+''&&)&""%(&!*%$+%"&("*!&'(%!%(&!'&+"(+#'&)$'*&#*!'#&$)&'"*$$$+%&$#&+#!)&!"&*#*%
@r6835
CTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGNATATATTCCGCCTCATAACGGTCTGCCTGCAAACAGTACCGAT
+
8:%!!:87,G*D-?*-6=0-?9C76$?@1BA17"G&3&'0994;9$&!.-16#$=<$E1475*"@/'!+>7B666&:-'8>@A;,63=9636!BC*EB3'=##1!($//E%<<!44B8?&H'#B')4B<)A52EF2"23/
@r6836
GGNNCTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGC
+
*')+#!*$%"&$'!)$"#*'"*)%*!#'(+!#'&!'%%(*)*!%)*#%*%+$)+'*!&&
@r6837
TNAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAAT
+
%!GC'1)/63;!(;C)?-='*):*)==B5E?:(%,D?<*<>!4!E#*;,1(30H(5-+((?3B>-D<H;E8@.*F53.*2'3##D63
@r6838
CCAATATTAGAGAGTATGGGTATATGACATCGATAGTTATTGTCTATGCCCTTAGTTTTGTTGAGNTNGGAGCTTTGTTTT
+
H1G33004?":G*7-90*$28.#C71G=!@H);3.B'1=&D74%<2E$"*AFEEF+2;0,?)'#A;)@(.34::4'BG$G)
@r6839
GAGCAATCGANTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCATCTGCCCANTTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATC
+
%+#%$##!#**&+''''++%&%!+(+*!$$**!""%%$&%%*(!"%(+%#()$''#%)#('!"''!*&%")''+*()#*$++'"#()#'"+(%&#+)#!#%#!%'(#&*%(&+#""&##"%*%$$"$")#)$(*&$+*%*#(#+$&'#+#$%&&(")!%#'+!+")("&$"*'!&%(#*)$)$+"('%
@r6840
ACTTTATCTTTCTGTTTCTGCTNCTTTCGTCGTNGTTTCTTCTCTGGTGCTTTTTCCG
+
0H?)%.F!GGA9=<?'6G>/F7;GF/;")FG1G:)F#85?A$@>>D7.'C%E*81C!5
@r6841
CNTTATNNCCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCT
+
"!(*')"'+*"+)$(!%)&)$$&&%""*')("&&#'(*%+&)%'&"(($#'"()"*&+(
@r6842
GAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATATGACCANCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCNGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTG
+
B&1@=*"'3@:$!B#'@A4A4<>0;4$F7>H&$D.>4*'5;B*C"&#011(D;>%6&!935H?&7EEE>F(F=+6$46)F1)C3%&GC"3(D.*G!&'(G<1=(.*+6F%,.D;F..;C*F..(0%)!D8>)F/>2F8-:=."&;4+"3BA?/G+7'%&E>0A$.4)BD<&B68%0&%$##)=9"(('6C(8-,9(<!/))25'$&.E;D/@E0.5GC1G+8!//1"1A%9*:$?&H6C;6G6@0<8EE$FD$%)1F292,('A(,04@C#%+<$GC4*:>'%G*
@r6843
TGTCGCAGGTAAAATGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACNGGCGCAGC
+
3>)G+7&"9ACEA,'7%=DH"@280<9,CC%<DC<-')&1A$(@956'1C*876-9!-F00(3*>F4#+6/(@04+)4AH:1C)H"H#+&%574!
@r6844
GAGTACCCTGTTTTTTCTCGTGTTCAGGCNGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCAC
+
-G:-'?+8#8;%/-#8C)--A.80G346,+CF,2?+1HD'(H1=2F;>:2!??3@A(1'E?=!1G)/6E-8:ADEH0).;035+7!C&*2<G
@r6845
TCACGGTTCAGTTGTTCACCCAGCGAGCGGAGANGGGCAATCAGTTCANCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATNACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGNGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGAGCGTCCGCATCCTGANTGCA
+
?.$<(>13A2CB7.".!.#.:=-@9%(('"A61(-,:0-.GC)=A):.9!.-@<>=18BCH;C@385;6E6)3?"AA<:0C8A5EB%A)93$-.8E5.C,>#=?A<60B.5!*1:#)*(F$&/**>G9&7E.(03.)2C3->@7641.D@E")4".!?6+;HF@F=4/-%G=8F+B14*"5-(4%/$GD381A.+55+3,5="),>@3AHG2?B3<D+A+GBC%:G"?=E%,3G$$0%@,H:"*'BC)/9(H>D961EB;CG!=B<A@
@r6846
TCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTTTTTTGCTTTGCTCGACATAAAGATAGCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAGCTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTAAG
+
@!)6F*=C4D'EE2*1H766@HG716D6:F>=*1=7B5+E,F"67:54;%?FDH<B6:A.,=/499%:(?E56'1%6!+9@5*@&A,,.9B8'1%!E%G33B16+H'0#,7BD8/3$!#+":&A7*$";/3@<&AD%%4#>+B$93$!0(C4G';)F@:48;>FC+?&9F3!8<):?,+#+/)3A4#%6D</%19A3AB-4$+9-%?%<7E9-CE)+E&(-$*8:*&'7"+&92*/*%89-@.3H,#<0-C8"'F%<:=9#<<3&-<-1*?96<#05B:95/G@7*?!56GC*62A+"9@23$C-="F6@6A$-C/,(
@r6847
GAAGNTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATNG
+
(&#"#++)"&))'()"&)%"#!%(%$)!%*$&+)+*")!(*++#(&)!"')++#*)!"$&
@r6848
CCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGG
+
/(<.#=!>8E-35C66)?7C-@,<(')$8;@2D;?#&>A<+7DF-
@r6849
GGTTGGGATCAGCAGCCTGACGGATGTGGTGNCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCG
+
)"*+$#*)&!##+*()%%"(!'!$"*+%'$("'$")'*$++"'+''"&#&&%&#*&#!**)*!''#'
@r6850
GCACGGGTAATGGATTTTTTGCTGGCCCCGTNGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAG
+
=+A*DC3;'2!9HCA&8">-4@21=6%8A9,5G"FE=2H8/C')*=,D89HG:"%982=*D(",;=#C<!=<>9/-223<
@r6851
AACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGNGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAACACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGC
+
CHE%C@'7;F3./!!8>59(GC&!1!+11:8":#%3D)?A8)E0,<B6('D?<D;H9/!2,E"8*1"?:D58*&'(,F/0;2F&B>F2)':4B:D/D;/&E44B41D>B77-<D?>05A*D;#'/+A-%8=GG*61'-9":<%G02B)3C@=,GD.8#>E.1-%A0F.@0D9H(%16<!6@?0D6&5(57.@-H!G1D46H87>&!%1/G>"A:14F-C>1),*8%!H*1(D1"E<%4E9%%(>;EB?$4$!9D-B"87%;60*2.%>5,F%-=F"$,3!0*><,"-31(0A4$)200.B:4&EF/(FH)+!"H%6',GD;@1D8D?,7E-28,<D$*FDE!8$'3##*>7;<$FD7:5=7)6EF=D2;:8<)6@C78A,/F3*:9%.1"/>6CFB+$'>;!'.,&E(<0-2>/4B7*">2*$;H8!&E5+<+?4D0.E+$8>F65H0C$HD!.+%)#
@r6852
GAGCAATNGAGGCAGCATTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGGGNTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTG
+
6*>F:7#2*C6(D@F,937(3F%E?,59,%.'B'H+CG-#'(9?%A.B011F,<!$!6%$AH.36D.=.H-;%C'41<5&70"9@;FH;A/4*=C)+9H&(?$;E
@r6853
GCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTNTTGTGTTAATGGTTTCTTTTNTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCNTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAANCGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACNAAAAAACAACAGCNTAAATCATGCAACCCCGGTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACT
+
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
@r6854
AGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTAC
+
8",4=*7:??+9;'#!>H98*@*?;##,E)G8>B$86$B!H"*9:H%1#4-0!D?+=H"
@r6855
GGACAGCTCCGGCNAGCCCTGCCGCTTTCTGCATCAGCANATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGANCACGGTGT
+
+#'&+!+)))$!#!)*%+''"%)*($)**!(&'!&$"('#+%)*'))"&&+'+%$#'!&$&$$"&$)"*+#(!!'!)$+%'!#($#"#**!$$)+&$+)*(!+'""&%'#!#(#'%("#&)(&'&!+)+&(++%")')
@r6856
ACNCCATGGCATCACAGTATCGTGATGACAGAGGAAGGGAGTNGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTT
+
"(!5"%::!H"#9&#"5='?&;&67&G4,&@"?$4+@=.*<+/'-7#7FF7D.2+G&!2$/,*8G7@C%==D1=//?)EA<@=+2**%1&;;?650<9497"?&"$.17&+'8+B427();9-E>A<
@r6857
CCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGCCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGACA
+
'<$C<,H87C2(A;@:1B&0HC?8+=.$1=E6:/956*!!=D!0D7+!%4;43#!3""G>.#6?:0'*)@=><),92H3&%$/+%C%<>-/@$,A(#0D..8@/:%;=&4@G/ECGB6H"/;>C=2B(DD"-D3>3)!+H1+*0;>!!A=.3:2?:0?!C)$E5#:D6E;@@)B&.=5)-08H-A@+)"@B#%A>4">@:'F%B'26BG0:9%%2&#G,78/("G1%3>.1-.+DD6F)49#-3(<A.1EC9/:F.<D->:(;-7D@.6H*B.-1!G+F8*5
@r6858
GAAGGGTGGGAATGGTGGGTGTTTTCATACATAAAATCCTNCAGGTCCC
+
).4C<8<'3B0)8+%*"%.>=&D7$-#H;<F3?B=4C/9.,E8H>-(CG
@r6859
ATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACNGCATGGGGAAACGCCTTGGTGCGGCGGATGTNGATAANTGGGCGCTGTATGTCATCGGCNAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACC
+
@!(A24@&02?56;%(6C&"%6H%D:HBDCG6@!)1D5)@2A!:5D(C6B3%+C>63@,)'1,?7C&*7%,<?9D@D>@=(=??>G>B7*345C&1*E"08:?-8H$@27H@HGED=33=6!2=>$..;9,#(&003%B4>4"&E(14&G5*20.)/A$GG6>)*2+%B,HE470<9>!<4C2FH
@r6860
NNNNAGTCACGNATACTNNANTCCGNCCNCATNNTNCNTACNGCACNAGNGACNCGAGNNANNTTCGNCNTTGNC
+
"$"""##$$!$!####$"!"#!###$"##$"#!"!"""$$$##!#"##$!##!"$!$###!#!#$$!#""!$"##
@r6861
CTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACANATNTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGACATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTC
+
8C%?2=AF"AE4E':?-0*>.7!6$>5?78/1(#>"))>#?$$HD<@E;C=@+%H27$5744A3?D1,;-'4,'"93%)")+H"B10!,93+C#1B'%%=83-G4/)$96/;@3E/G:61B;=F3)&'%H!$C,AC6%0B7$+3D,*H=F#FF416,)$/+!3(65@>$H4DB'B19F*H+,0"4H;%DBF2E?(B/<..(7FC3A>5-8?0G&0>8%$+?2%
@r6862
CCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTNAAGTNGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCANGCACGTTGTGATATGTAGA
+
6)3#%A>+$!)+84-5#6:,A,.A-78703D:)2A?9F,4!EBG!D8!=<$%E!'4C,6F=1;4@57B/802F!5&.)/(<H7?7-4:G)F2?(#.5=?B.9;&'6B;!7%D9F/<<5,#6=87F!D..36,93D4!D6
@r6863
CCCTCCAGTGTGAGGNCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATNCATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACCTCACCA
+
D/"D/>F)4*,H:6185:*D03%8</%-8F=($B>/0)G27E=+GF1'**>4="%>D?#(E12##C8C!4;$:'/+E:$4=F!6=F-9:E<G%?-G>,A4#*.F-'*"G5(+<":#%%>/>09F,=98B-('>GB"28G9FBE
@r6864
TCAAATATTCCTGATGTATNGATAGCGGTAATTCTTATTCCTTCGCTA
+
/#;2,9;;(?(%C(73+-*(&42H@)/=5$"121C'%:5'!;&;/110
@r6865
CCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCT
+
-0C4&B*<+-+E-2*8!??.-G$6B-@DAF4$'A@6F#2E"C'0$#5%A(&.,>/.1;*<D,!%-4;3**'2<.9;?16.02DG
@r6866
CCTTAAAGACGCCGTTTAACATGCCGATTGNCAGGNTTAAATGAGTCG
+
%()(+%')*$&*#!&&'&!$%&%'&"!%#(+((&$$#$"#$'""+"##
@r6867
NCNGANACGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCNGCGGCCACCAGTGCCGGTGCGGCG
+
'%"%)%+*%"*&&)+!!%)''&&$")!#!*#)&!&+'('%%((%$#$*$%%#!#*'$"&#%!%"#)'%&#!#
@r6868
NNCCNNCNNNNANTGGNNGCNCANAANNNNTNTATNNCCNTCNNGTNNTACNCCNNTGNTAAACGNACGNCNNANGTAGNGCNCANNANNTAGGAGGNGNNNCGNGCNNTTGNGNANNATNTANATCNNNTNNNCNTNCAACAGTGNNTANCGGNNGTNGACNNCNNCNTNGTGNGGATTCTCGTNNNNTNTNNGCNAANNT
+
!$$#!#$##$!"!$$"#!$"!####"$$!!$#!##!#"""#$!!#"!#"#$!!!$"!#!!"!!$"!#$$"##"#""!$!$""!$#!"$#"!!$##!!!$!"#$#"$#$!"#$$###"#""#$$!#"###!###!!"!""#"$#"###$"!""!$!!$#$#"$#"#!###!!#!"#!$##"#!$!$$!"!!$!#""#!"!"!$
@r6869
CANNNCANCTTATTTCGCCNATANNGTNTGTNGNACTTNNGCCTGATAGTTGATAGCCT
+
''!)")"'"$"'%(*(#*(#&)"&"!($&($&$$&"%&!(%&&'+&()'%#)"&)&&*(
@r6870
TGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGNGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCAT
+
0=":&/G;=$;+>G6,$A2H0=2;$>D>%F2F<F,4<A8&&?))$4@#CA.<78(-/$1-'D7<C!=>.@EA-(2$7:!<>"A#:%57B=F'D8).@#H%=G";8(B:<C%-H#>%G*F,-@2+F=
@r6871
CCNATNANAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTNACTCC
+
((#$&#*"+%!(+*'("'!$'%+$*#")(%)*++$('&!#))""")($$"!
@r6872
ACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGG
+
A0=#.(!;72!-**=@A0;<EE##*!'%>876.+A-(A3?*E1"97->&1FA1..F?/5''@?>"6/H+$6HGG4CD
@r6873
GAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCAT
+
=?(G>$@G$..)>5@5,+3.>8(#//%.&'&H2?6!?AD:%AH>3.$*-"
@r6874
CCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAANGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGAC
+
%/HH?61!7)H;BD)>='-H0=<-)3);>5>&8&%?+&>G=A:&A!,#9!%;)5-D(*$D';;H<A.(91B9:+<2DH)B"E:>C6,7(,->:AG39"8;94))571/>-4*8-/H;=&@1C==;G1/6;88A&.4'*+(,G,6?28C*(%92>$0=C$1+0)G+#3D,B$7
@r6875
ACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGG
+
)C!-&3C8A2HB!<0)B6+'#'$!?+79--/0;7F"$D6G)@E=2C1$8=-H1'3E/C:"D,&F0:'5E.0560787&@=.32G4?2.>7,%=>*53"')=48?-@CG:&);"C:F&7->1$443*?$>*.1@1@34.*DF2')%-0.@(C/F"(4?$1&0<$5"6':#E+H*$F("*%*,)&-38@"!4>62'47-$HEB5?''*)A.$%#@E@=B<HD--)>.)=9$:!
@r6876
AGTNNNGAANANNCTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTNCCAGACCCAACCAAACATGCAATCGTAGTTACCATTCAGGAACGCAACCGCAGCTTAGACCAAACCAGGAAGCTATGNGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATG
+
*$)#"#)(&$%"*+''(+#$))&'""*#%'&+!!*+))!+"+'#&$$*%"&$!+)')"(+'($%+")'*&)#&'%%&)"'"(&%$)&'"+)"($!()&!'$$#!&"#&&)!+$)(#(*!('(!!*+$#"#'&+%$'%(#"$&$%!%!$#'&%+"+$$!(%$+(#+&&$(!*+)"#+#+)(&$+$#*(#$!*#&
@r6877
TAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCC
+
(9,-A<)@(?,(=F7!G>39<H&,!>>%!9AE;F.A?7@HA;$25#F1GG6E4)C7!(E6;:/FC($
@r6878
CGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTG
+
E"+??"C7.<,(8)<ABF?*C-?BE="@&A4:'.BDG3;6>550<D@@&<<2C?1@4-FB#==/'>/3D6/2*@"()<.0,F%9<+
@r6879
TACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATGATATCGACATTTCTGCACCATTCCGGCGGGTGTAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCAACGTCGTGGCGGCCCATAATAATCCGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACAGGCGGTC
+
10G=D!@-+)<ED*+-&8=3"18(+!!18)*H2.54-G:*BD24@1<2*55"0.H=4*/6=$?)CF,%CG7)(.+'$8)H4&?9D?=1D4;:+*7!F$)(>8&%=C9,@1"->68D16G':D;;:#:5!9HH!&&#)(<$*@;')*:%%"(4#&GF#$B6<64H?1><-G1G+2F>@">+#=;?D+C)E;&4'3AF=$7.5%B62$'=F=HH69.>?1G<:G,D(55=!03#:%18&#"$4@
@r6880
TNCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGNGGATATTTACTGGACTGAATTAGTTNCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCC
+
D""$8G+6BH"'=:5B$.,&99<HE$E!#63AB*>1&FEBH,9GBC1)E@@454;3>$;?GHA,*&6/%>!*&>H=F.4>*/,".BH5DF80D(G/9>&%41HH;9!+D46A(9!1$7:@.::9")(.3#=$/"$#.':CF5G:893.9(-=E<5/3H0:-=C-8.,B=!<0>2<&GGB0AFD/.;.8C9%E-$;E8@C(2:4
@r6881
CCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCG
+
*/B=/4(F0E9D9(<?8;@>&?<>$-+*=)>(@6A+''-'0D14643G)$("*1=
@r6882
TCACTCAAGTGCTTCCCTGCCTTCAAACGATACNTGTTAGCAATATTTAATAGC
+
-BE:8=/G6D(#C!-54E#-,($HC##'6@GA#G#3>?C$(#;6<A+'>,5(E2
@r6883
AAGGCGACGTGCGTCCTCAACCTGCTCTTGTGTTAATGGTTTCTTTT
+
*+*$+!&***&*)$)$&%'*"$*+""'!#*#'))""%*'#%#+%%%%
@r6884
CCTNGAGGNNCTANTCAGACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTT
+
*)%!%!*(!(%#"'$"%+')(+*%)!*##)&!#'**%#"&##'))'*)#*&#!)()#("&#)#&+"'
@r6885
TTCACTATCGCCACTTTTATNGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTAT
+
3F=.3-!D0:78E:/@%/F*/"=@);!-"/:@-;':9-D&3%F6)+H3<20;9(:D,H/#
@r6886
GCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTANGTCGCCGGAAGACTGGCTGCA
+
5D!D%*5.(F13"G<F2<;!,"E$8(6+%7A(*),,@$>33?@+>#<F,0$=#%1:.H5E<&G"5(5@=/!5%C/:,#-7?B.4:40.)=!$1@/'27.422*C%
@r6887
CCTCTGCGAGCATAGTGNCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCG
+
#!+*+'!('+#&*$"&&()$+*$!*)!&"%%!+(")+!*#(%**)"+$*'+#!$("&'%)!'$#)!#&+#'
@r6888
NNNAACATGNAGGCGGAGCAGATTGCGTATNTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGT
+
""!')#*($'(+()++)'$)#'+*+'#)&!!!!(&(!**!+&*%('&+&*!%&($!()'($)&%$!#$"##%)#$(&'(!'&#"&"(*("!&((+$")&$*%%
@r6889
GAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAA
+
.0>H>(E,?)@/.D70+'18(,<6&8CBD&;!G<92)?8C%/=AB5A!+0=!*D74:%4%'5*C,?=4(3()@)"F'H!08/-(H"$2/<E#=8*:AF>/?@C9E3,*707=";?=;<=*5H#9)2BE+5)+&"-G/619EF?*?:%2(*6,&)F/<:,7+!>F?D+=C?@<F=4!3104C67<?7"+(=*'>H+-&"2H'8(/>=0"1#56=.14,"F4#FE,
@r6890
AACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTNGGGGCCGGTGNGAATTCGGCCT
+
')+)))$$#!*++**&*!&#)$''(($&!''%)#))!%'"+)*#(&+''%#*'"+$&#+)*$%+'&*$"!("("$*%&)"'#%)'$!
@r6891
NTGANANNCGNCNACGTCTGCCTAATCCAAACTCTTTACCCGTCCTTNGGTCCCT
+
&*)!('*!'#"$)""+*+'%*'!#*+*"'&)'$))%"%&!(%#+)*(*)#"$%""
@r6892
CGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCG
+
B:18-1&36"0,)G=-&1:30.870G'B&&,6%-*4,D-:@"?'/3F$)%
@r6893
GGGATAGCGGTNAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGGAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCAT
+
716,<>=D8#%!=35!>5FB8,'@<#H;-=%A?A79E2-@1H$0*:#+F8@3*G),E,A8."*';G7*"/>.5?H8;$F+33>.EH,674/+F.8>"/%6C>4)42DE0E8$*9%';:GA)9:=EA:A1#(24++5D79?&:15&%1C32+,+F;,>.<%/,/=:CF6>ACA/@F2C)")B
@r6894
CNCATGTGTGTNAAATGGTTTGCCAGAATTGTCNGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCNTTTGAGGTGACG
+
%)!)$(+!'"#$!'!%%'$)+('%#'"!!'%$'''$*)$"%$)(!(!)')!((*%&%)&+*$%!"&'('%##%$'&)(*"!&#%('#+*'!*&"#+((#$&'*&+*
@r6895
GAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTC
+
FE=--F>.FC"8*'C1$)D-*>,<@;.<$7A,#@H>HGE%'D!00./?,@.D#:/2!496BH(
@r6896
GAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAG
+
CDE?"B'$H/$8&,;.(E,"7-*8<1+/@835*AD?!?<2)G:A7*)4;*(F-A,A
@r6897
CAGAGCNGGCAATCCATGACGACTGGGGATTTGACGCAGACCTTTT
+
E?$862*CD8:F0*;19-,@F>"%-0!4;<?DF=,6D8F>.%);3H
@r6898
TAATTNAAACGATGCACACAGGGTTTAGCGCGTACACGTA
+
AB;</#B#7=*"=>%)%E'1#D<=A:>+'6:<-;FH3,F6
@r6899
TGCGGCCAGAGTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGAGGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGC
+
;@),%=HD;-1,##7&*)?:-%31C>?D(B6F7G.#-(*";FH<5*#;)(C!.((E0$9$,D?7A"!<9,8"430*-<,#FA,F$H&)#4>:+E;97B
@r6900
TTCATCCATCCATTNGGTAACGCAGATGGGATGATTACGGTCCTTGCGGTAAATC
+
B9&C7GG-@6&46+F29%=!)AC><?9,GB=7.+F*0%(>62('<*D0@)8#/&7
@r6901
NNGTATNCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGTCCAATACGCTTACTGATGCGGAATTACGCCGGCCGCAGATGAGCTTGTCCA
+
#&<DD5HA$/32<=F7!!!!C78*?@+&>+<"(<&,>:CBA@.4>%A8"G6;-+B@F6*(>:+G"BB*5E/59$7/?9"ABC;!=)>->0-B3<(G%242+5?485)!07-=5/+CG2C9C;;786GDB)28E
@r6902
ACACCGTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATCCGTGATATTCTGTCGCTGCTGGCGCTGGCCCCGTNGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGTCAAAGAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTC
+
-/&&9C3#,?*0?39C$!#(%?<!6>>!-4H5(G-B7,5;,66FF'-<?,559*&)'F31A"D44'),72#.05G+*0(7:00@;!-G+17">")0$9+">&,?H6?;@9D9#F76-4#14"45*B$&G"2.1/8:G"03,?*,$>31H*1,@*378(A/9D4#6>,+<C#$(9>95",9+4-:):/*&1G"G!,2%B2A8-/AD.2D=6@?'8D*3B09,%+:+2)/349C"7>-%HCEC-GF+F7>"#9H=@2/<-+.+>A0=C5CE%#BA7).%=F
@r6903
CGGTTAGTTAGTATATTGTNAAGNTGAGTATTGGTTTATTTGGCGATTATTATCTCCAGGAGAATAATGGAAG
+
9)+:4EC=$5H:GB52,:H%9DG"D"+8-2$*<8,)+2B+.*C=@::/2<+97/4#;-HE<(C@1-9564#'3
@r6904
GGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTC
+
A85-.)1G.=32'.;3?-=E/?'/H4C92/.BG<D)4G&2"<#+=(706*B#D>H8%-?
@r6905
AGGTGGTAAGCACTNCATGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGA
+
1?E;",&69057C7$0(#695A3(7>D251H$>681,=#(15$,B:;';':DBF:9=?884G?&%/1?1%3,F@%A&/0=0(4@A=A=6@$AHG-:.:*=1D<;"H5179(95-((.
@r6906
CAAAACCGATCTCANTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAAACCATTGACCT
+
;;3-2?0D<7>A<=6"=;1H)/,<-/?%:5D=7$/+2*==".5/%"B<>/-H?4><=%@*F1D(!C4H,$B@?EG?19#7#0&'CH;
@r6907
NGTGNNTNNTCCAAAAGGAAGCAGAAAGCTAAATATGCAAA
+
&((%$**$"%)*+#*+&"#&("&'!(+%%*'$#($"!$+#"
@r6908
NGTACGCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCG
+
%C'E))BE0+5>&!DE;2/BDB60D:G5<@C%,CB&8*#@73%">9>,0&2:D)-
@r6909
TAANNGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGNACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGANATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCAGGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATNTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTT
+
(""%"(*'''(+*&++('#)$(+!$+&!'#$)(&"+**++!))+%!+)*'*!(()'+""+%!!($'&!&(+&"'!$$("$)+)*''$#)$"!)($"##!%'*("!%*(!$#*!#*%(!)%'%&#&+*#+)$+%*"('!&&$%'!"$)#+(!+!''+)'+!)%&'$"&!##"*&($)#)&#%)!*$"*'))"%%*&(!")'"'$+&"+'"!*"&%%$!)+%'$)#("+!+')!&%%&%$)+%$"!%$*+"++#&(+
@r6910
ACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGCATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGAT
+
1!<**4(-+-@G:>/=(=334"-:4!3.:)3F5/F5C.%1F$=$G2F!=#H3G'EGB28@%&B@)&$(E;)+3"G<*3+73241!3C$D/$)E>;&G&"!G,83"#G@FB<#(C1G95)$6%=D'1B77@A71B?3=#;C=&2!>'GG
@r6911
CGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTGGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCC
+
@+5<!.?$(:!+5BA@+9"/HGB0'<!E-;'+)0H:@B>!%4!)5G;?ED2G&-GFB$-=F+''*+2>5F/89:D
@r6912
NAAAGTGTTGGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGAAGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACC
+
!"&+"(+&"'&)%%(#(#**+#)$!%''&%#&+)'&'"!#*)())!&$$'("%*)&+!!$"#'"#"))((#)(#%(%"+*$'!")(*%'&")%+'%()#)"#+$"%!$%'""(!*#$&)%!$&"+'((&(
@r6913
CGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGT
+
96-(3<**(D!9-+*$8!&<3:"08+"9256>B@*.A;6>4/
@r6914
NCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGGTTTGTGTAGTGTTCTGAATGCTCTCAGTAAATAGTAATNAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATT
+
,#;/G56:0*()7104#H-733%.",3"5;3.B:*#"*98C&';!.8G%!;>.B6:2"+04<-''6,3/>ADE)DG(-+"40:G?H;8HD%:H$+;:>'49)'67.(?!G<&+CE.<F%+5""B)&.E5'1><
@r6915
NAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCG
+
!G:4G9,3/@#-!@=+)#'>#52@D,B<F-!"(D0E655<E;<H@<&(!)*0G%B2F&3$$@%#F$@'?'&00<#D*1%>%7E7*G11'+",1/>)#/<<F2&@+$H3/EGD?7+994+4;2F2H80?#@73;&E0)3'%,E.#@."45!%>";@H<,*-A58G-+2D?*#<
@r6916
TTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCT
+
D'A99;,13,$2@6/>35;55D&>)!/>E0.*!:=9/'<)!:%/#0#>"/&G$9AA/.HBC=;H6.F8$5A*/%?1.
@r6917
ACAGTATTTTTTTCCTGCCATCCACCCATTTNTCGACCTGCTC
+
$''D0#+*'E'A(:8=B;F"7"10%$?@6=)?2'$7H2A*-H?
@r6918
ATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACNGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAGTGTTACGAAGAT
+
D?>2738G.==C)=D3:)EH6$%(13-)8*!-)GGD+B?.%1/!6BH+(<>;2AH#GAC.&G5?')'@E8.=&"H7=".E='/;)>,@/2*.,4-E:.=6#7H3,'D>2!)-H+C)>?7AH<<('#G1+E%,C./,$.($;&?>?1>2%E'FB%6A569H#0G6?!5G=3<!.3B->;"1'2679#+
@r6919
NANTGCCCNAGNTATNNACATGNAAACGGCCCGCCGCATT
+
"&!"*&"''$%!$&%#!'$!#+'"*$+%"+$!!""'!#""
@r6920
TTACCGCAGAATGCAGCCANACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCNGNACCGGAAAGAGAGTCNGAAGCCGTGGCCCGTGGTNAGTCGCTCATCATCG
+
D3=5"4=H''&<#8C&-)-9:9F,$5/</<D87)>:-75*/#/-$B9E>$>@)9A&3,C/'8)%H(,DE/;.6=>D)$).#.;=H!725@(61H9?D+D8?:%/A!3EA73GG;F+<>4EG
@r6921
NGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGNAGTTCAGCCGATCTGACTTACGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACTATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTA
+
").#,C))!GABACD,"@$">.*C5)7CD@0A/.G#D?992B<:48/=0<%=D'!7@660-)??A8A38F*1)HF189:;A%1G(%%22#F)-=/E?G70=-">A4D@)("9/!H4?/DHH*#$3;'@->9=F.3@$C3@0'53=9"&+8<2::9A?*E5D8,/(&%;B!2*+8,B,3#+&/7B7G9,*%'.D0EH8E=1<"DD%*7HAH(:(*/C;*/E:6B"/E2"8+-'E*CC%;!?G<#E8F.>9+-G(%:5C/D,$F96?A46E2)"8C&"!/-!/$'6'D?-G>-2A8B':<1(79C,G"0B55.((GG34!9*0#>25:846'
@r6922
GGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCATGA
+
'5"A69>?)8&F0=?B69%H4H(C+!@")F?(F3D?2(=+.5!
@r6923
ANCNTTGTAAGCNGNCTNNNNNNATANAAGGGNTTNCCGNCNNNATGN
+
#$$#$""$"$##!!$"!$!$"""$"!#""#$!"!$$#$$"$!!!""#!
@r6924
CGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCNACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGC
+
G>.28GH)BG6"HFC@2->4C!>A!%&@.D7;,*,323&=%2?5.E9$$FE4-!*'&8"$&(%A&@//$@3"%!(A+
@r6925
CACTGAGATNCAGCTGCCAGCGNGAAATACTGATGNGCAGC
+
:*(";<(C)27!8159/5,)?3'846>2@>?F+DC)(>>2"
@r6926
NCCGTCCACCATCGGACCGCTGGCAGCCTGTTGCAGACGGGCGANAATGC
+
!$(+'%$'%+$*+&""*%##$!(&$!'!*!!"))#$&"*)&$()!**")&
@r6927
AACTGATTGCCCGTCTCCGCTGGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGANGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGNCAGGACACCCCTCTCAGCCGGNAAAATGTNCTGACCGTACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACG
+
6+B+<"*'$-#$8+5>H*?HE>D!5G=2/<!%9?D*8H.?F&F5*H>EF16?;9<(D@2#(;5&/.)FEA//7,.)50><$<?A2?/>'FH@#!"<$?4>71+5'$>;3=/)G=A8A<>+#H10"8::4)?*9;3E>#$G/,<2BE:F;0C3E+,>7-#=27B%10(B@9&-998'6;5"FF<.+%?3*$"7=<.(B;8!+=#"709%5<"?@-E(F%43)$'F:%"1G,<!<%H55$.
@r6928
TTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAANATTGATTCAGGTACAGGGAG
+
&097/8)<C0?2D413-2A;A$$,1!+C6859A!.!*D*?3F:,816B,=0$G$1/#'%<!=7CH%H!E,2C367!"D-412)53354*)7@$)*172>"C@D$1!81=;C@
@r6929
TATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAA
+
%,#F'4EA?/G$;-0&G25)*-5/:#7.&":H;@76!H'&6?'*7*A<."0<7<343&!;/2>5:C,#>G-45-EH3))8?1*;H1?$80$23<37-&%H3%+D/A7#%,#$(H)D&+&$,77%2-7F'2:>B2:?";?.4'(#G33EEH!*-?/2-$
@r6930
NCNTNANCANCGCGTTTAAACAAAATTTTGAGCGGATACGGCGTG
+
'"")!($(%!&&+++$'"#%&)+()''('%+#)'*(**+"'%"+"
@r6931
GAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCNTGTTTGGACCAANTAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGACTCCTCTGACCAGC
+
:,<-()/EC'EE'9//6-0(0*:*7;5H;C<%30'?#742,2((/-*'B=0>0BD36!1E418-'"G%C>)$)<1<>,(=3A#>$22$#02&)@F;("*;?>#3402E!)>?;A2F@?9:9,?6&?CFC&$AE1);,E&*C5+*5@,8G7*3#DD$#?44#*2(FG/89*.=4,CE$@.:3028+H@=#)7"&<'EC&".'H78((*3!6$383.(9*H72C4.H6)H5D&B@**@-6
@r6932
GTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCG
+
27;#D6CF$&5F85?%9?%BC$AA%&"A6@)8<FEF'<>9$93-4<F8!@!EB@G8"!7/AE)='DE33=7EB+HC,>52.=/7@1$>
@r6933
CNAAANGNGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGNATTCAGAAAATGATTATCAAGCCCTGTATCAGGNCATGGTACGAGCTAAAAGATTCGATNCCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATG
+
!'*&$$&+&#%'+%&*%$*$')!'#"%"&&"*!$$(&)'#$(!#(+"'*'%!#'(!$&&#(%%%)#$#((%'%"('&+%+(!&)!!!%!&!#)"#)*#)+)+(&)++)&!!)%$)"&+%!%))#')""$!!$'!!'!"#&(#+!&&*"#*$$'""%!"%#'++#'+*+($"#$+%+(#'%'(&($&'#%*$
@r6934
CGGCGAGCGCGNCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGC
+
/C%9>57>:0E.#@<'A%@7:;B2,?=>,(H.'HA-B-27::BB=F@93EB-H72D=4307(E&@#7&&?-H4%.9F!@>,>(+6="-*>=%1@4</)?EH(0/+01>2+7A@6?E1"&5BE$C:,AB=F%)598A:9-CA4<3B>C(:0(F
@r6935
GAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCNAATAA
+
&87(@$E*/>9&HH:FF?F4>32;0DH@CGGF%B&E*)7"4C&B?3E037%<<80<)15);BB
@r6936
CGCCNTCTNCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCT
+
*(%'$%'+!$%$"*!&*")*&!$&)$%&%%"%"')!)*!&&*'+%!")(&+""!)'()'%(+"&#+%"*!+!
@r6937
AATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGATGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGNGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCA
+
.H&/6?;:@A5G"/74<8$$)!F<?D1=E0#>(:>(BB"2</7@.2*@A5#<:=$2<083A'<$+/1A@1B2#CH77!%G8=+D47A"#39>D,>;9#E-="(52-A/HGB70A+!EA(0)F#<#!!16.75EH#>/)D+(08/:'&93';.&7*H=0.<)66&2)G&&<@%%.AH%<$#;2/B8/<H*9-4%=79,%?041>GD7?B*B>8(5#600#=>$$)C73FE6(-=#EC!1*DHC4H;9E,5<<-%6B2B.G$&808@+D,$A+6C)7#$:8H1;,:/E(-#869583GC&3;"7D65$'1GH41C?:(*")?'F2>#FB<G53GG4HG))#GG3*4./)EE529,@?<0#5<;3(%/H,&-E;%26&-:(BB-$5,*D;4(+2A/?81$2";1$+5*='@*>.)0'>4:"=C';8=.4)$3!-4)@<';1;!E0$4@$1
@r6938
NANGNAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGNGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTANTTGATTCATAGTGACTGCATATGT
+
$'&'%+")&!&%!#$&%&)+'!%+""%$#**"!&%&'"&!*)$#)&'"($'&"'&)")#$+"$&&("*((&$))#*"%##&&*$""%(%)'$''!&+!+&!*)$!#$#!'**%&)&&)&"(!'*#('$*+!)'#$('&)!()'&*+*+**!!+'(*$#)&)+#%*(%'')$$"*%$)&()!#%*(
@r6939
AACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAAACGTC
+
)+%!!+)$"!"(%*!!)&"*()#**(!)())+$*#%%!!(+$#&'"!'#)"!&&"!)%%&&&)'%+(&**#+#(++
@r6940
CTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACTGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCC
+
E"=A!7$*&@F1*+6$;>9!*@=*,>;2'/2)@0**/+<4)6EC3HH!4*=30<4#,/':>/$G1+))-H+@CD9@3>E7@3&8=$
@r6941
TGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCNTTAAGGCGNGTTTTCGAATCTTACGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTT
+
".B2<<)7(=FE.%D%5%?E3*8@$$$-/9)'GC>6.G)>B,E0:#*2BD642>&9))AFF<6+0A%&,6(G6D&F<%6C'+'&:E:,.%C(44*/))@)G@;-;*+#4(C))A';/D(@7@E
@r6942
ATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAA
+
9"A6/G*=@4!/>;G/,<.-HDD@9:+:D2;95?@H#H4G1A<;+H0)0'0+?D'1;3-D-*
@r6943
CAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGC
+
+!5"D"?,%F8A$.A=>'=+&B#.6:E8>!!1C):"8#C*):7A7569%&!#:@<'$%8%D4<<E!
@r6944
CACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCGCCAGAATCGCTGATTCTGTCTGTGTCATNGGATTTACTGCGAAAGT
+
4;/G12@7!@.=168@H7C/:1-1(0$E9C!.??C2A6">?AF"1*D22(C3+$<7"(8!!)?@8!-(,)63B",="G!HE9(5;?;&*+
@r6945
GAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCG
+
*!572'3#=F<4,.97)'!#D4),9<=/$H01)='B=!;5D"H"7A*&)DB':?95=,>;4+
@r6946
TCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCG
+
+&,:/<D:0/5->*#&964GC=A>G6)BF@/HDG)"-0.,49<7H*)DH&!1+63A+
@r6947
CCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGNCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGAGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGCCTTTGCCCGCCTGCAAGCTGCGTGGCCACG
+
E+<E#-#!G71C;>+B,(%E85*4"=1*.$4<:$%F/(5>H@GFG+AE::)58E<;HB;-*#?67BD$9/<"2-C5F19>.9F$?7?:-'!<0:D)7$*$2:A-=D8&,2"':;*73E6?!C+;9+,F178F9B<(<;G*-#F2?<A.,,8')'5&!#1-DAG!6)=:E@))>
@r6948
TCNGCGATGCTGATACCGNACTTCCCGCAGCCTCTGTCGCCTTCGTGGANGCCGTTGACGCACTCCCCGCCGC
+
("!''*%)(+($%$!#$#"%*''$!%("+*!(($("&&++!&&!'##('!%"'+$%!&*''"+$!'&$'##*!
@r6949
TCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGNGGCGCTTCA
+
&<91FC5:&>.>@.E8<1/2@:20-&@+2.>/<H.#C&&?&*C0@*.3+?4-29B8G
@r6950
ATTAAATAGAGCAAATCCCCTTATTGGGGNTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCAGTGCGTTTACAAAAACAGTAATCGACGCAACGATG
+
F#':F*-)<(0@505'$!.$('"E!4?07#8=6+#4.8C"0<@;E'&5;-E?,4+69ED*A3%.G4-G/?#8H/BF9E*0'2F*14?;9/+/><.(;GG</DF<($D),1'A("C8%9<,..16H@#+$5*F?890CC><&B<32DC>3@A/7<2):(;-=%D:@>(:1C$,D(3B,7?2H*?4F+
@r6951
ATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTT
+
?/!$H!)*$D<+:;H:'4"3D'*D?>:D9.</4<?9-;"HB194D64!/)$&%H!5/BG(5"74:>G?%8):;1='#D>;.FF55=&A=B73<9=9
@r6952
TCACGGGTCCAGATCCCGGTCGTTTCGCAGATATAACGGGC
+
+*'#'!**$('"#'*#%%$%&)#(#!'%&&"++')#'+)*$
@r6953
TATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCA
+
>9E>F>!?;E5A5(96'*,887G<90,!'$/;?=7A*-@F9!*+%%C%2;#G/C;
@r6954
ACAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGANGCCGAGAACTTTATGAAAACCCACGATNAGCCGACTANCCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCNCACCATGAATCGTTTCACTNATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACNGTGAAAAGTCGGTGGATG
+
)##696@,A0E3<<,,:=7#;#+;<")/&=/&CE0%5G:%)A;5B""@18$C$5;/BE)>.02@%"6?G/C0!+'C3>,1G&+,F<E3/E40E3'$?'7>;>/>F;(/,%CC@F(=)/5#7=22F)3E>'A)38FB6,#D;A&D)*/$3=/1H>BAE921;G*@#%CA=6H+9:B6!BA-;9/*3"-63)&7:?B@;:)5?!D'C-+2=8=5*E#)H4F.@CD'8>+?'D3-G&:5<171F
@r6955
TATACCGCCCGTCAGGNAGAACTGAACAAGGCACTGAAAGACGGGAAGATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCG
+
::$!+&'-:-?G-:F!&&6)!?F3?)97DC?/-C+/15?HD:9(+FE,"5&,-91-,.;-ACAG%/8D##7(/;,<,8E-7.$6:=H96)!;9:9,)732!#G:D
@r6956
CGCGGTNCAGTTGTTCACCCTGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACNATGGCCCCGAAGGGCCATGATTACGCNAGTTGTACGGACACNAACTCATCA
+
'&*'*'$$+)!!&#+&(!+"#'#)#'!%"*#%)+$#&&&'$(+&))%+*"$"!(%+(*)%##%%"!&)**'!'!%&($)$')"*+&*%$%'(%'"!'")"!$**%"**$!&*&+"(#(#$'+(%$*&!)(
@r6957
GGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGAC
+
,;*F"ED<$519806:-"4*DF06>(*DD/H33#149A)*F.;;;3-&$=5$!G:<4(<,,,8-&;257%79&3+"8>
@r6958
CACGCATAACCCTGAAAGATTATGCAANGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGNCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTA
+
/A)=2C"+19;CE(?:+?#%%AB"26H%%='7!&96<(2@8@1F447?3?".,C=E-$//:'B;"D8H:&;<H,DC06!F:,=$'@2D#%:+,2$:&F'@!:+0A*'6G&=>H'7=..7'+<#G3DH@5"D0%)CB(4<D4:E4,76$4!%04@'/F8""B&%;#9@06GB(#4B()-!&80B*@@B%*78D2(6=9D),,!?0)=1*7H"?+9:4=2'@2'3D/$0=;,A,;/&@/B'*.%<#9#/<D4(=1'2$@HGE,+HA:++<?A":/(<?5;>4AC3HA"8A!7<.365*'+
@r6959
TCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGT
+
;<&F=0;"B1(A@C64#4GEG</77B)9)B3A,7#)DF+FD?'9?8D103*#70DB*&5)!8D<G$#AA>1
@r6960
TGCTTTTAAGCCAAGATAACTGGCCTGAATATGTTAATGAGNGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGT
+
$F(;$B.;'<.G:->4/8D8F)0?:#D&B"H6-($.8E5,<8>=C4BD-1#B9G-('?G$0&?E;3H:!".:!2/&1?';1;/%AA3>>@")!'F7/,"G31-F5*'2;
@r6961
TAATNACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTNNGAGCAAAAAGATTGGGCGTTATCAA
+
)"%$#+++*!&*)")'&+)+#"#$$#()*)$&)(+#+')$!#*+(+!+%)'#)*%#%'"$!%!*"'#+$#$!'(!("$
@r6962
NCNTTTNNANANCNANCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATNAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGNTTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGAC
+
#'!'()#*&%&&%#(!#)'(+($&&$""%(&&"(+'*%&&+""+(*%+&)"'$%(')*+#()+'("#!'$)#)'%'#$$*!+"!*"'$#'&*($++!+)+&!!*'!"*$+&#%(+('++'&!)'!*'&*)$"("#'($(&$("&#$"#+%*++(&&&#)&()$""%#!%&'!'%!!')'%*#$')"#+#(#)*'#!'!&)#)**(&#$&"$+)"#('*#"%++#+)$+'($&*("'!"(#%%"!$+"%'###'$*%!)$("&()$%)!##$*
@r6963
NNTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGG
+
$!-'/91(D+:<801/83&E*0&191F<&<:>$#*<4@:E:%
@r6964
ATATGACCAGCCAACGTCCGATANCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCA
+
3%5/;D;&AD.<!26C4"G-@5-(,(4)"B;A6$::5&*%29!"(/&4H?G0G'?E)<0'99)#BB?EB(F:>;@$=(CF%)!#8"4;=/8;(B(&HE!="0;=5'-A0(1,?37/97!@567/#$'D//.;=2,"!A/6>%:?A,H0$&G3D(2-"G*-E)3.(7C.B<&=39)4&,-CA:%&6,G-B7@;/91(734?9?&>138-
@r6965
GTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTNAGACGCTCTTTAATATCTTCAGGAATTATTTTATTNTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATNCTCCTGGCTTCATCAAATAAAGAGTCGAATGAT
+
8-=5:1@$/7/?B&H6G<2$(!&'G.4%-5%5+@C1+.#@E&+2"D&8;B5*#5%HF8#?:0=><$0,5;>CB5<4:$2&@4'/78DG.(-@900")#!/&2.B!=)+84*@31.A+<,4#BA?'B#G;G6F:D0'1%%-)*3'7D-/<;B6E(C7B0@>.5!B>*;?:>:$9F.<!("5G)'+B*D
@r6966
TTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCANTG
+
@6C"GD?E=H3>D879&$+8,E<=4)F&)@#*>%.&?7D).18H<,0D&.5D5"$<:BBHHA00(1A0B?@8440)824&-@F,!B*D;#
@r6967
TCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCCGAACGTGTCGNC
+
74D7@=58/656H);$:0!+&<<264?H>,2=3<E)"%;E;&%"G1!(D+1B4=A$;>@E1&?*7%2140)(5161+A*$G00>H@#*G4
@r6968
AGTCTGATGCAGGGGGCACCCGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTT
+
)*4#?8G?2="59B'D&;?E+?,@&*+A!$9?.+@=$E8A-%35$<#0;8"@&":F$93'19-.?GC':7?C/-A.?#H0A;F!-E>)62"<):-
@r6969
ATGTANCCTNNTCCACTTGAATCTGAGGTTCATTACGTCTTAACTCTTCATATTTAGAAATNAGGCTGN
+
'&!)'#%!*$*+%)#*$'+$$!)%%%+&#)#"$'!"#%$#%*$")%!(!)&#*$)($!!!$$+$&"&("
@r6970
TGCAAGACGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACC
+
<E=$;'!+97'%HF;@CD@275:9-3%,@?9./:GB/C1F#6>F,=G'01,@+(F>"=2';&;,/=94+!(@?/D<.>9E"?0B93"6;
@r6971
NTTGCTGTCTTTGCCGCACTTGCGGTGACACTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTC
+
*)+%*)!!&*"*#&+#!&###((%#%'"#!&!&)#"(%%'+""%%!$"!*!'!$%#+(''*+++"%%%"'$)#*(!!+&$!+'$*'#&!(*%%!)*&#')&"$#+*#('!
@r6972
GCAAACAGTACCGACATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATNGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGG
+
:(=HA*#2?9)40HCFE.@FFA77-*?+93'037?8!>5-7E517'&-/(3;>:@%$$-&E5<(@2?27680$3,?)2,02!@'6:D;/C/&>*90)F"DF$?A<8B%;?/H??<=%5&($;3#A9,1=26@:%1-?A>3,2#5&+-**21,/@#??>+1-%3&/-?"7!$A!.)9F46H2/"'483+4<:7$)5:!')@9.;)*9C1#B,-&.0%90B:*"$(6':()+$G:*54:"
@r6973
TGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGNCACGGGC
+
GDHD,D?:!@'?&/B#418%&4"9%?>4=-!"27'1;:@6-22)?<+428"
@r6974
ACAGAACAACAAAGCTGCCTGATANTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATNCCAACGAGTNAATACACGGAGCAATGTCGCTCGTA
+
)6330D5$09/:#86)F.G*16//7F96D4>-0G&G&$7*:(9/*,F+/C7>(<.!*<'-B"41(G.+4-0>A3(*F%'AE%9%,G,7$3(%@+/-?<>1EHG1G#61?DF8%:
@r6975
TACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCA
+
H"6'4E3B#2,"6@'7:2DA!A/72$6+</5<+>$147>;DA2H+=.D=$:5.&<(2"<*
@r6976
NCGTNGCNTNAGNCCACNGACTAGCGATAACTTTCCCCANAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGTTTTAGTGGTTGTAA
+
'&))*('$*$&#)%*%$%(+$(*(%(*'%!)"("$*&%)!*('*(**(#%&'!)$%($'$+)'"$)*!+#+&**##&&#*"")%!%*!"('"%*#+)
@r6977
CNGTTACTCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGNACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCANATCATCCAGATAGAGATTCTGGCCGTTANG
+
'#*)#*(&+++"%$()+#+%(&(!#$$*(+*&))+!#*''&%%&%%&($!')'%!($!&%!(+'$(%#)#$+&$*%'#"($&$!!&)$&%)!(+(("$*(&&%(')!&'%'*"(("#%$'$*)"$+*"&!'*&+"+!")(+%$'*#!)*&'"#*!*%+"%$*#"*+#%""!*+%&*'+%*))""+&'+"&&+&!)'#'('*'#%'+&($*($%$*+%#+(#$*($()&#**)'#!*%#&
@r6978
TTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTAC
+
E,HH,$@+?8-5D&(+!9'16"$7H-+8-)EGB@$!&2-<"8%39@%<!8C$=!;37!#5>.E,+642C73&:>A7//4!.
@r6979
AGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGC
+
'F>+-!#&82?D1H;>#=B+?925:3C/A.#B,/A17<5%+D!3#678;&#459>+/;;';B=
@r6980
AGGAGAACGAGGATATTGCGTTAACNGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATC
+
58?6D:E3BB&H//)*0A7=B*0'5/6A6&@=.B&@,25>B'G-1%A:BC21E:!@=.D;0<5>
@r6981
TAACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTANGCGCATT
+
(!%EG?88E"6-(&9GEGE"243.&C,10+%4452-.+9D*+1:<9/#;:3:"!BCC0@E52$B/3/!D8%E#)-B540>@;65H@3#3>!22743+*,B!@@<2%#
@r6982
TTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCNGCGA
+
F4=6B-580H+#,DB1B2)C;54@+=%!=/45G,#5(24GG:A4",H)H5;46'%?57*!17+(&6$'<"53(BG&5H2#@*>3:/6*9DDE?"?.1
@r6983
CTTCCAGCTTNTGNGTANGGGATGCGGNTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGAT
+
$($*)*'(#'#)"!'$*!+%("$#%*++"!)!*"#+#($*(#''"$$$)"!')!'$#%+('"#*"$+$''"#(!(("(#*%*$%!+#)&''''&*'!!%)'&%"*&"+'*!+
@r6984
TAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAANGACATATCGGTTTGTCAG
+
*8!'D0>FF+3;B6G+"/B;+0$.C/@$;B;*.F$2($>AHDE7'=263>)A7)20+B?9/E6!++9,@G"2."4):?61C"BCA)3FE(
@r6985
TCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGC
+
G/@76:-.<$89H35(2#@6'3B!95&?><8;(B2:/$2/+FEH>)/9#0;23((+H%!!8+F/)(:)+#B>>ACHGG=B7+
@r6986
ACTGGTGACCTGGAAGAGTTTCTGCGGCAGTNAATCGAACAAG
+
;.@1G=@<7107=)##17*:+5<D?A-&**(5%#.4(6,!.D@
@r6987
TTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGNTCTGCGATGCTGATACC
+
>@9$34/"=G*<9H8.2<&G$;4=G03>/+!C64,'>="H:E9E74$2D"?>G,5>A9"B@+="%F*0<@9C*3&A>82!A&8AG.9+@?2)#C.3E-77BE.C/%3:$4+.62;;,"<D&5:0C&+110
@r6988
GTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGCACAGCATGTGGCGGGTGACG
+
7-0'6E.13"%.5&8="8AG3E'<:H--=)GE!)3#-@F6+@$&A>>'-1D(39$%=A81AC
@r6989
NAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCG
+
!<47%@#G/(>/A40H4@:B'D3&>(+AG:E?15(F6'924A>%7?F<E<6';;?,4A/G%(63&,>C%%,.E:%)$',!H73/'F"131C0F6962"9'4=<B'+H$%3(B
@r6990
CTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGNAGGTAAAGCGCAGACGGT
+
8-1-%?8!5B:<C)"*"17>F"4EF(/0EH43':3;89%D;F,'?D-%*=*'00A*+-D:)2=H@@ADDD=0*CA09!2273F6CGF,8>')0A@8.DED/F"+0F@.%9!-#D=@&5)1-'!B%?:!B!-=><5"$GC(?#,?/"98D0!=A&3EG=AE
@r6991
ATAAACCAATGGACAGAATCACCNGTAACCTGTCGGATCACCGGATAGGACCCGTAAAGTGATAATGATTATCATCTAC
+
A.@C&2H'A(5/989&/45E,?/#B6:72/B/+=C!$#BDF(<&D;*6!,88&.60H3&D.$C'7(+#61C=&-7;3+-
@r6992
NNGNCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGA
+
'$#!)&%*(&)+'!&+**%#%%(#!&!$!$!!&*#('%($)*"#)$&
@r6993
TGCTCTGAATGCTTCCAGAGACACCATATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGNTATTAAGC
+
&:D?-C6%(*#&#.7*@7(!$%=*&:&&:$B;HA!(FD$('8+%'$",2=D,@)5#'2+A?H@-.H%#0:=55=.F&3;)F&8$=
@r6994
TGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTANCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCC
+
9@H&+%5B3A+/#("$+0:;8A3?B!;B29,6.3%B/2D$"+*B-,D720GF,/$GH%:=;/,#%%%B$8$$!,8",)7!H"E!<'>A2
@r6995
CAGACGACCGCANGTAAAGAGAAAGAGGCAGAACTGGCAGACGACACGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGNAAAAAATCCATTACCCGTGCATTTGATGANGA
+
(("'&*!#'%$$#)&!(($+!#&(!'%*%$%!"+&'%%%!'!'$%+)##+('&*!*#*&(!$!&"%!"+#%(%#&"+(')!()*(!$)!'%#&!%#$*"$%&"%'%!*$)+++***#$"&$"%!)&%*&*#"*&#&&+'(!%*')))%#
@r6996
GTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGAC
+
(9,E!E@:+C6?0,AE/'&?91>E"F>4C=7.C<G>28E6->3-$H3)/$/.@3-"64-(;92H82(9B88<<1,:!4C/9#79/@GA+DF:8D==:9;*4&!%D3F3/4BC;<@539DG&/1=G;<;
@r6997
GGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTT
+
6E%'HF)0$<<<0:9:F%7'36A.42+,,G@B.C+314&:)(2
@r6998
GAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTACACGGGTGGCAACAGTACAGAAAGACGGACGAAGGG
+
$E046%(7*1<*849E(>#?)F'A+4<$%B6/<?<F)6E5->=B.!/H.8+;E&/E*(@?+E*"=(!/$&2;>&A=15*/?+!#G-A>*8'4D?"?C<7
@r6999
NATGGAGTAATCGTTTAGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTAT
+
!9F!54A"%&&5>B6C",@C'F!"61+'H'#:/FFE>'.98173-.4.$@6;E#2='/?3BE(/H;E1(')F&**5#(G!&&:6D02G*=@$#H'&$',$A2/1%.?1,
@r7000
NTNAACANGNANNNTNTTAATTTNNGAATANTNNTNNTGNNCCAGNANGNNGNTNCTCTTGAAAANGNTAGNNANNTANNATNNGGN
+
"""$$$$"$!"!$!$$$"!$#!##$$$!""""$#"#!$!#"!$#$""#$$!#!!"#"#$!$""#"!!"""#$"#"!#!!""$"#"#$
@r7001
AACCGCGACCAGAACNAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGAAACAGGTTAACGCAGGAATNCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCA
+
;8,,8%"C(6GGGD:0D))G3$@.>/40)<(!$9$H"(?G-.G&=3++4+!/H1";=:H+:,#=?+2!E/'CCD77*+A=?+.%!;A&,+F<?$5F6H$!6H!,(44->4!@C+9:!A"'G66*1:"E@!<7;<(GD5&D5>5CA5
@r7002
ACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGA
+
C5"F=FC2)"<@A$DH$1&0$#8CG77?1!-AF"/:=C.42:@+H=D*B32GG+=>4461*",83H;3<1")$5,'@=.4E(0'3F<@H/#)6#@&.?'&9D'";E2@7,:
@r7003
TTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATC
+
(2BAF.:?;*!2:9/+0#B:-93*BA,-(5$>2?AG"/(?H)@%'E0H4,$(*@@;,383.?$+HC793H67G',GE$$C!F?E%9BDAEA1?%CF$9;?D=?>AG'*4!2$1879G.H!=.&AE5;@66F3@<?@<C1'996D,E'D7&(&D95CC-?5D(./>D<43"9B)"!/G?1
@r7004
CAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAG
+
,*A@+G#A+B7+($8$E3(;;<+E73%;>H21-E9A$G4/9=8:F
@r7005
NCAGGTGGTGAACGGGCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCA
+
$)4E-D'2%'$.H75*@4'87F=3"4/ABC;4E@!=9"GC*1?&%+2'1)8>8%+19',&<?CG%/.=G!$F'@/?+4;>C$$2A<4)C==BB(H6?G6@+'@!683/
@r7006
NCNATANNNNCTNCTTAGTACATGCAACCATTATCACCCCNCCAGAGGTAAAATAGTCCACACTCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAANCANTAACACAAGAGCAGCTTGAGGACGCACGTCGCNTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAG
+
")!))$"!!$$&'+)*')%"'"($($+""%(&*&!!%')#%)''!"!+$&(!+%"!&($(("%#)!!)#"(!'$%"#%(+%&((+*+(&"(+*&#+!'()#"(*"!"'%((**&*+#"$&&#$&(("*%(#&!$")$$!#+%&#!&*!+%)!!&%#)"#&*))"%+"*$#)&((*#)+")"&$'#"'(**"+"+'*&$"'&!"(#!*#*%()+&(!('++%%
@r7007
NGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCT
+
&<"38.E:&"71*1>G<?+=46*@2E'H1A205)$EHG-;>+C5;>3H%,$!)H7/.=H9!B%:6C&+49&'7'7#!55G*!525D<3;4.CB.$E?/1!F6;1:?)E;
@r7008
CNCGTCTGCTCAGTGGGATGCCGGACATTANCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTNGAACTGATTAGCCGCATCGG
+
)+%"*)#'#)%&#$('&+!(#$"*(*)!#)*)#!#&&$*+)!*!#"$')#)"#+*"***&)+#&%)"*"++!$+&&+'+%**%'*+$'*%!+)"&$#(*!$##()"#)**)$%'#'$*%*)*!(#)%*(+*+"'+"&'&&""&!*'"("&#'"#"*'$)
@r7009
CTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTC
+
H6->H,)&@>C8@18@(27/+3">B=>%941=G,%A?HD3&=FA%
@r7010
TCCAATGACATATCNGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTAGGACAGCCAAATG
+
F5?,/&;5A6<?B;/;#B5E(A?-(4&/@$<)):D:;@1!>>2$,E*?&54.;ED7.5<.'C@%'5BA-E89=D)!0DG56>A/A1#B&G6,6FG;H*99D
@r7011
TAGGCGGAACCCCTTCGAAGGAAAGACCTGATGCTTTTCGNGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCNTTTATCAAGTGTTTCCTTCATTGATATTCCGNGAGTATCAATNTGCAATGCTGTTGGGATGG
+
040G+0/C7,7EC3'',1%4F"*/:@H?B:1:6.@@(-4&F!%4)>C)3)5H/8"$/D)#$3#+%1%0;3%CC$HA7'9(DF6.!1A?75D"/F3!&E-*$0/,*3C3&#$+2E;#-,&#9'%>31H;6G&(5#ECF%/!%@#>5-.$3+4214%*&=G@!64-,$'=,57E!C)68=5C%F<"$5C,@#B0*'1
@r7012
CACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCAT
+
2&5#G(F-B,701/',*+.0'.,-3!2,>/>.">:(F4'=H#F,18-+).%"+9@6<7')2D*%#&@%#(15*;,6DEF&7&37-6"A2,G<2@F#
@r7013
CCTNGTAGCAAGCCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTGTTGCGACTGTTAGCGCGGCAACGTCCGGCGCACAGTAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATNCACTTGCTCCTTTCAGTCCGAACTTAGCTTTG
+
?2A*,.#2=D>?B+005?B4:%-5E@G;%/>2H<"/G<3"16D'%A3(5G38:A71)!=94!G5/!*HB=30<5F%'*63B%;A6=*64)1!E.'D77C71!2#..)4CHA?7&0G=A7)0$C3%5/)88)540DEHB?(@*FED56.1G12@+((/-+/?..A23&7B'37A!%!F6#*B/-CE(DC-/<+B0.G,5E9(F5:0).$?1BE,,E3.!#?)2
@r7014
CNGATNTNTNGTNTNGNCNCNGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACG
+
)!(#&$#&%&))&'&*#&&'+&%($!)#'%#$"*$%%*$'&!#$('$##*""()$'$#*
@r7015
TCCGGCACTGACTGGTNGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACNTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCNACANACACCAGGCCATGTTGTTGCTNTATGCCGGTTTAAACGTTCCGTCNCAGATACGGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCN
+
@*#*,,BCG07+D)#=3:==++>F1")1"?4AD@G3G%CE?GF8$=*3G>24C*,&/*6:9H$0!:,G#03:/59;():BF4'0-3'*3<67@6*?*:-5@>#0!>/$9$*#(13A40<DC/"<C6=G*='03'1-;H79$8EEGC2'A%8B.HDF#7'-2>!"=2B#'!$?;B$+H)83=H7;=56+;0)F0$<-<A5-,"0EF8.(C),
@r7016
AGNAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCA
+
;5!+1!<,4.@)7?3A"=H'7#HE';D#C(*"780E%;1GG6=9#06&1/F622C2EHG!'B(<
@r7017
AGCAGGNCNTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTA
+
'78DD."(C0)?,#5#654?'E5HD6HAC"0&4@*+61H1%"!9F$:8A0*6GH*35<=8CA$B)H?:09<8#F<22?E"D1><-!0E4%5
@r7018
ACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGA
+
$H("5*F0('?H@6BC5("7A$&103A4D$DC%@55A(;)1G"0GF6,;%*1:@
@r7019
TCTGCCAGTGTTTTCTTGTTGGTTGNTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATNGCGTCGCNTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGNGTCAGTGTGAAGCGGTTATAAATCTGCTCTTT
+
CC<0!)*8.C)/@H1=CD"=B-G@@98)%#FGC?&;0#A#(!*+CB87#>)%&-).C*4F?@G@,3G8$=H<H)"C:8?H#!"?<>3H!&B6)@FG;>GB#8=(*'.0C4845:9:10;0/*76>!1='59!7693G2*8!4'*G!,'GBC.00D3D>@E90A5:&-G:$A#=A/@?E!GC='6><!*65%7&>?B*))8)"H47&EA;E!1+"-G.84$9742G?AB<%"",5==:64,B(B.:#3(>$G%;8D+D!7970CAH#(;:##5"@>3C,3.C*/21E3.!>E)-HD@.5,#8>:7B3+*/>1%G45&HG05DF%GGG?')
@r7020
TACCGCCCGCGAAATGCCGGGCTGATTANGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTG
+
)$'+$)%&+$+#&(!'$%+)(+#%*"&+&&#(!+*(+''$+#'*)"%*!!!(&(+(%+'((+
@r7021
GATAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGC
+
%FD8::9""9$=/'79/-.:6),/"G:?AG%4<..<2);G14%=""3!<#)='D"1E*;G('1%!
@r7022
GAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACATCAAACCATGTCGCTGCCACTCGC
+
00/!6HHCA3,+(A=C?<B>7>#3/62)'HG>60@=(<?3>9@74G#<#CG9G;;'?8H3('990HC-?D:H4?%=,*(G1$H6/-E4<'?*+A#&(98;E#%702#/
@r7023
GGGNGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGANAGGGA
+
)7A*4G2'"G;E79):<'9@8BG-#>B3@9@"8*24:,$'?.?C4E7,'A161
@r7024
AGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAA
+
."8:;4E*/#1(EH6#9>=&;$C=C9A,&-#(9C>'/2EC;AH7=!0&+C?6?@9,4""F>1,!6",7:H2-=B40GC-C&A%09==(/>?&,D77'G20<$,3D;;"B2E#6#!9F@&0-72D8+0$-3D1.9;G!*1:0BCB?;2A/2B1<A45+.2E1?1*6CC(9-*&07E)@028!AA9:+
@r7025
TTACCCACCACAAGCACGCTGCCGCCAACCATTCAGGGATGAACGCTGCCCCTTTTTACGA
+
??89(>)*4762:"HA(G7;@/!!6EF6+#&'3D"67&D.0E>-+@86'+,C/01A0#+!-
@r7026
ATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGAATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTCCAGCTAAA
+
B<+G,$+/1G"?4/$=@/!8B*E9"3=C0G#(!&-09C?-H4/E%,7&<(1%BA!BG2'D'D56B:E)(25*5D#A--8;+C3%2>BC)(EG17H0'55>A%'(8!?@F+AF+@/AG8>6+E8481"(#C+53,HF7,3C,$9>20-6A(*$BCAGG??"F44H$)>%99
@r7027
TGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATNACCGCTTCAGAAGTTCACAACGTNATAGCAAAACCCCGCTCCGGAAAGAGGTGGCCTGACATGANAATNTCNTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAANTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCT
+
$$&*++'("*&(!+"$(!*!+&'#!%!#()'"&%((%)'""'#&"*()&!!(%**"&!$"%$#%!$&"))"$'#&()&#+&&''+'($&(*&&#$%%(**!*+&$!($&$&%+%$&'("+"()"%!&)&%!$*%+*+(+&*"+#*"%*#$%++!!$$#*"!#%'&(!##$%($)!!!")')+($(!*()%&#!)+#*+##$++*#%)'%'#*)*$(*%'!*(&'$%'+)"$*&+
@r7028
NGCTNAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACNATCAACCAANTCGC
+
((!$"#+"&$#*)'+(("&"#&!(#&*#(!)")+%+*#!#%""($!)*%"+($+++(%#)'$!+'$#)**)*$%$(%'#%'&*%&'&)"%$++#&(%'*$+$*('($#*#))""""!(#%+%*#$!&+&)"&%#")$"*)%&&#)%$&#+*(&""&"*+'*"*(#)'#%
@r7029
TCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCT
+
2?,2A#<5F<$(,H+:"C?;92/&73:<41(20C=24B=4=&;#@>&03.%'3%7117&,-'4877:9,D503$"/D((
@r7030
CAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCACGGTATC
+
+'**&+&''$%#"*%*&"))''&%*'++!($*%+!%(%!)%*"('#*#
@r7031
GNGNANTGCATTTTNNTTTCATCGGCCGAACAACGGTGAAGGT
+
'()!%#$)))%$$%#+"&+**("#'))%*&#'(")%&%*#")+
@r7032
ACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAG
+
=,6CF6F;09<-A1,?9&.863D7;2D03CC*A7*&<9/$"A1+5-AB)/E!&(-A57<>G0$AB'67%
@r7033
NNANTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCANGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGT
+
#"+E77C$*&C<A%!G1>6999+$<"3C2-!#D&D&G:!5>A8&#>%B$%%:C)>.B=G*#!=98<HG%%=4D;"<768;C7$22!2;!@%0$-+GG@/-2%=B3$=B&(
@r7034
ACAGAGTCGCCGTTATCCGCATCCTGAGCNGTCTGCAGGTTCAGTGAGTCACNCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATTGANGCGGCAATTTCACC
+
"*!$%%*"+%!$(&)#""!((%*!'#(*&#!#!*%%'#$"$+$#!""$$)#!))%**"*'"!##!$$+*#'(#+*($)"*#!('%('$#%%&&++#&$&*$(&!!)$$#+#!*!(+!*#+&&#+'!(
@r7035
AATCTGTCAGATCGGCNGCCCGAAAACAGTTCTGGCAAAA
+
;-CB2C?G&-2.0,1E8A':<CF0H+5?$9B#/&#86()"
@r7036
TACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTNGANAAATATACCGNCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATG
+
+E.$=E5=<!;0@))%'!@(&".+B;2.++4:0;+%0+.*7;,C8;:B=#'7*1*?4'A)&7073!622A;1=C&AG7'-<!A.>$:(GHG''#+'&9C8G2)++*-F%4>B(.GA8F+A3**/#>0*,E563=(&$8+F*')?91+!>%7B9,+4F/)#<C?!+0?$B;E'*DG$
@r7037
CTCGGCAAACTCTTTCCATGCCNCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGG
+
1:-*>)EE9H-/GG"%##E&:0FC);;C#+7#&(.04+?!EA6'2."5@C:+:24B9@)6.7452$)%!-E(=$2-."/"G?'<96=7@%D/D@;D>C@;E,7
@r7038
NCAGGCGCTCCTAATACGTAACCTTGTCGCCAAGTGCAGCCAGC
+
%BD=8-6@>@-G*!,D@@EBF1-,>H39:=4("6$.2*<B;<G>
@r7039
GAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCAC
+
8)G+1>/-,.=GAA&*.+5(5@"D-19/-H<+1G9B#G15'>?C<;1H@2<6(.,$G$;53B@%.=61BC%C>HB7F)#=E$,+F$=<.*##=D>1G(3)$)<
@r7040
GAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATCTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACAC
+
A90$2'5;3/F(;"6196A"<+9EA0GGF7$>.H'3=F$91F>H!>4-94@)$G95@;81*,>!4+:4>'$D:9./,)/-A>/<FD!"CD-&!D%G<$0F:CC,'G!:$53!/43F+A1<!#:+$E<F">284*5=A;83D!:09/(*8;4E7G)"*/-7.<+;9
@r7041
GCCAGAGACTCCGCTGAAGTGGTGGAAACCGNATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCC
+
C-@#!B'F584'D(DBE23G&'BH'(/H.,C/HF@G4E#H>739$620+%(7$5?=;8,1+A<4;D&A73#&9%.B<)F9G1(H+1&99?1F/&-9CHC)!?=A&,B-59&>F7*30GG8C:-?/+<E2#4*>BA2*;G"#'CC0;'4;)&,0="@<+F)D.9A7%2$9.6(91.30#GA4B5EB;/E.D$+6&5-3'?C70!G,+<3,-/<F'C.*6C;"=$E6#H;"/F:)#00'-/?G%<$B54*0&)D;;&H,:)=;@@&;'6F70A1C1&%5=3=1A/F%A/#64?G:;33=8;0!$F&HB11%C63'0:B$<<>!;<6%0##1@#0:<A>7)=A>
@r7042
ACTCAATTGTTCATAGTGTTTACATCACCGCCAGTTGCTTTTAAGACT
+
5,A94DG@56A*4%:3G2E2=9*FE<&$:!,3=&($@:9@8"!8B6/=
@r7043
AACTTCCATTATTCTCCTGAAGATAATAATCGNCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTT
+
'.<?%;AD*46=5,=8/5!<>.%5E<@!F)G%C1D?4;,09B3E'B!E'((>E?)5$7@:C':G"7E'B8*/E:D-25.9@648
@r7044
NCCTNCTTANCNGCGCAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACNCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGNAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGNACATCGTTGCGTCGA
+
#'%%#")*)&*$+!'('"$*!)&*(#+('))*#$+!((!%&$%*%(("+!*$&#"')*&(#')&#%)#"&")+%#("#&*(+''%%"$("&$+&!*%("+)!%%%"'&$&)%'*('#$"))#%$)%+&%'$!&!+%%%$#'("'%!')+$+()$'&&%&"
@r7045
TGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCG
+
"+'(*#!$)+&'+$$%##'+(*+#(*))%')#*$+&#%(+#&+&!)'**#*('!#$$!!%%(&+(!
@r7046
GCTTGAGGGTGNATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGA
+
$32/EEG7$)3"%%:/0<1@:=$"A0AF<B$F8?8)B-2D,+&=23!(
@r7047
GATNTGNTNNNCTANGTCNTACTGACCGGGNCNCNGTCCTANNATCCACNCCAGCCGGACTTCAGGCCTGCCNTCCAGTTCCCGCGAAGCCGGCCTTCAGCCGCCCAGGTATTTTTCTGCTCTGACATGACGTTATTCAGCG
+
&%%$"#"&!#&*)##)%(!(**($$%''#&"*$%*!(*$&#(*&$+"+"("+(+&#)+"$%"%+*)!))!$!!'#$+&)"*%$"))&#"(*#'#)%%+#%*%#&"*"!$")*)'''%"%''($#'(""#"%&$''*)'"**$
@r7048
AGGGCATCAAATTAAACCACACCTNTCGTGTATGCATTTATTTGCATACATTCAATCAATAGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAANAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAAATGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCG
+
:%A-3#+011/61$7)94@-0G?12H28@)4HB2.E)H%A=556G,87!5,=<%-';>$::8EG';8B%-":0)E3&=@E=F4;E"44,FDH32*<.F7:2-'E=D9)@@*$*5;1EE)!:!#&0,$@?4>5CF,A'E)A(+:,EA/-FG20>#A(;6EE%!(##D?!5.1:)*%BHDB(69%>;*/6@AE%1%<'87
@r7049
CGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAA
+
++!;*,;#>6;(9<E4+8-?D-($-(4BH'#%C+):5,(/'E%."1";&G#&*G@3H&#G0
@r7050
TTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCA
+
10+*.#050;8!51<++*F*@$6*-6F1DD6)"$:50'=+
@r7051
NTCGCGGTANTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATNAAGATGAGACGCTGGANTACA
+
&*+$!+'$('")'"#'*)'*$*+!*)&%)$%#$*&)%"*"'(%++!*'$%'%""*&*("$"&#"*!&&(&"!%#()('&')+$(('""$"'
@r7052
TTACAACGATTTGGTCGCCGCATCGACCTTCGGGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCNACACAGCTCNCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGT
+
'(<+;G(?6681>6?-:+:!,2*B$6!!190F5<5!>7):10!)C"05D1*=A?9$6"0%6>9,)1G.6*;4,/9)!A+(A)7D4H1'*'?0)9<;-/$H+=?##GA!#H+:9".>#8",D*29>5C*:0.>&D4!".%()@@9E#CA
@r7053
CACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCNTCCACGCCAGCGT
+
HH*%2C,>C18*?1%291A,F&$;#57345H=B>2H<45,%"23H4"%=5
@r7054
GCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGG
+
2(G<-;D4C*&0%$HG?=D-4GD$?DBHB.8+:G=H$2D*B$)-D*(0A/
@r7055
AAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCGGCGAGGTCGCCGCCCATCCGTCGGNAGTCCGCCTGCTGGNTCAGATACAACGTAACGG
+
7-+%=?2A-=A0>0#*;3((8CF;$;2>966>->&4$?(!%.?/G!5:#EE=*#&D'A5G'($;D#E"0D+%!E196147%+?"/,$%H3+/4+,*7CC1,7!<#9H<=45=GF"H(".#?2
@r7056
AAACGACGCAGCTGACNTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACNGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTC
+
<AB2/!7AB=4>CC$'GH7,B"5&F9%$;)*@)3)HFA""%61'$A50G47')9DE:7''>8EE++"7:?-/#5?4&;$8F4)&C+E,*85EF'E7<*A,4$90;:7)8AA5'&<968$-'+G)(F4.FAH%-2+
@r7057
TGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGANGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGT
+
H74B4/$4G">*8-5"%-.H4F?E-<.%C&9=H$A%5))'';*E1$0A)7>70@=9A(-:3+9**909145$1;G2895F7%&=#5@<+&26+37H72DC>4.>,;'2/B5.-+6F5A6*97%BE1<8*F11"'50@50)"@56F,:F0G-<3?E.&
@r7058
TGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACA
+
4'='+5.-06H'9!?,42B;#9;=H2)<'"-+*$..7.7+)'*F-'F9(,6F<%#'.96%*B"1*,&6(>0-732!'<--0:F(G
@r7059
CCGTTTATCGTACAGTNTTCAGCTATCGTCACANTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGA
+
&+5-$9#<A.#39%G/;4A:-C*.1D+1(2'0HA%6+<:.(G):<<%%%B:22)2-962<&71.(GE(+-$A4
@r7060
CTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAAT
+
7E""G2%C.7+).$$8=D=-.#6)-=D0CBB"B6B81<G8&B%'7,(1A*BHD$D3;@:)#*"))=4(6$/#'?<;)@8'
@r7061
CAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCG
+
.;E:.):>%5<C/.:A?8'4"-+>DC!*11=H!CHG94./4#)693574%.6%!";GB=)"
@r7062
GGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCC
+
75H0?D/.$.:.-2)G-),G=0!>F05E8!,2/$C0+A+#02HG1(-D60E7<=8@A<=#")!
@r7063
GGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCANTCCATCC
+
@?493D9+.A-DB=#-E)*'C!065">6#2CGF9H4H&H$>"-60G;!!&-H5
@r7064
TTCGTGGTAAGCACGCCGGAGGGGGAAAGATATNTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCC
+
?DE3"FC'%'D!A#'1:953?@1"E2$"!7(;F:=%2<,>E+'3.C5D4*<7"/=.9<:)$=?,2//H+=8D=3':,00D95F*H
@r7065
AGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACG
+
HCGG*"55F!/B0<:0B-8G,8@7'2(%98?52#5-1GG6"7.<8><6?2:%,73'"70<'91/5C@,5,&6@":&$7>+=B1A2:(FC?'
@r7066
GTCGATTCCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGTCACTGAATANTGCTCTTTCCGCTCTGCCATCACTTC
+
,!B)>@5B!G3$"1B*B*@BD9>E4:%*DBEG,A%7D)A1$ED3*(G:E8.E2!)+<4:$(.:::/*73F%%B-%8F5
@r7067
TAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATT
+
E!$$0"D<5"DGHA2*C%?+HE2.B2/-4*D((A;C"=1+(-9'
@r7068
CGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGA
+
=6/:#)#"6)%:D-'G<(,F$'AAA/BG2A;E@BHA93-'>8&<D:?#9CAF866?&#
@r7069
CGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGNTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCNAGAAAACGACCTTTCTGTGGTGAAACCGGATGC
+
+-)F/()B4*;-<;?G+G<019#1%CCG6H<BA)57,!E4/!EHF1=BE388/G66:=,=H3,/'2*;E>E>%0;</ACE3-**#A2-;%2G/?+5:2E-*G8E:20D'*%93F?F$#+,,29/.EAE=A"/59B$.G=F.F%E#E847"&4$#($"6C+$:E&@(,1C'5DEB73>(E5G&)$F+'0?E0,BAE#:BF1D9@B";CD=3G4-HF5,*F7GA88;<B"-!8")78@.:?G-454%'.7?G#!4@%-DE;A'&3D>9=
@r7070
GGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAG
+
B40<?.!182'&--98"-HBC)<&<&H;3"D+>;?8H;;.@B:'28&D!2':.8=2/<1?'A@F15C@4-41E&8>;+*<:03
@r7071
CACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACNTCCGGCGTGAATGTTACTGAATC
+
)E%&2B'9G-$#?0,5>?'+)0;;:1?.%16?!<9'("AED64:7HD!$46<@FG"C647#;:7G*$3?:#:!,G&939
@r7072
CANTNCCCTACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGNGCTGTCGGTTGCACTGCTGAGCTGCACTATCNCCTTTCTCGTTGTGTCCGCATCCTCAAGCG
+
*)$&)&*"(+&&+('#*"!("$(#*'")$#&")&%(#)%)!+$&'(%%))*'""+)((%*)''")))++++"*+*%%*)"!#$!%$#+(&#%('"&)++('*&$)&"($'$)()&)'()$#"!$$!$+#&()&"(")+++'*!'!&'*+&%
@r7073
TCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAA
+
6F;!<7+8=-(>E8.F(=!%"?#8=-:-1'7@2,)(@0@;?H6D4?<FC
@r7074
CGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGANTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTNCA
+
H8#D3@%8+D&.#-+:,7*DC$)4);A?36,5EG8(/4;&=D&EB:D?'A.G4;D&C/)4%*D+!#00<=%-4>E40$"D1;;!-8E3,187;4%H+#-9?(8G-C(=&?,1#7!3%%&)D64
@r7075
CTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACNTTATTCCTACTTAAATAGAGCAAATCCCCTTATTNGGGGTAAGACATNAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAAT
+
9?<;&>)E%H'6'*&:46F"GG&AD@>-8#&;0/07,;90-F%1:G)&+"(B<B;1$H%'A-B.?*G$C?/B#B)(/#,0H/F@<1A==?7"?)@+;=()GB$>C5/<=;$6@9//*>%8*5&7%CB<<)=+CB=":?9=9H%)8*4:DF(+.$6(&)>27D/5#F82-82%E*,/0,&!H((@&;#()C:D3C9<48<!@'37!1"?E#,F49="@A/4=897C--5%.
@r7076
ATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGNCCAGCGGC
+
&2-1$5*&*2&H>'AB:&'##!ACA*-1C-$$A$+C+H)5439(74*<G+A<=H=5FEF4/&HA@9C=0==13-5&'#<,;=$;$&(&-*=4;-%%6,)5>:9G$'/%8)A%:69EE,85.(E*)AB1@D!5"'6<;"":2+B3.#)B5'(G&H#/D6!2CG61G@C48<B46,,1$?+()E@$!A5!+16<!D1==/5,8';!,,.%>+,4/B=04920C%@-;1%)1<A8@(F+
@r7077
GCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTACGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTTCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTNAAAGTCTGACA
+
BAD=AD+H@5!E>%(+5==:!.17)709?:9BE#:H%(?"$H+(H,85)&16FA6C=HDC1=**;%6,-'3-#H5C5A'$//'@"++777-2HHA#+9-FB'$*412G?1(D$&;=H:=G+78'7<B77=-$7C*.7!?4+F)*,%6(<?A&*C@>)AC,&&B!,/B?;(0&#0*>B8ADFH=/?)"F=
@r7078
TAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCAC
+
%"0H$B;7C7E3#H09"G4:1E79D(A07;5@#=FC<,=/09F&12)'=@2'!0!23>"6#<2>$FB/C4+*8D?:AE8G4
@r7079
ACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAA
+
4/9*+,"AG#25H,D0H+-#-384@/&=D)+H2+G$<<>!'.;G$8/"26?'
@r7080
ANCGGNANNTGAACGCGNCGACTGGCCAAGATTAGAGAGTATGGGTA
+
*"**)%&!!"(+#+*(&'($'!)#)+%+$''%!&"#"##!*'#%)+(
@r7081
TGCTGCTTTAATGCNGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATG
+
<E"2&+"&#-"A+5;AC)@B$:)G3A3#0'F@3$0C6):A$$5C)DA!(:=@/:/F+(=71B
@r7082
ACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGNCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGCTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGNAGTGTCGCCAGAGTGCCGCGA
+
($'(+(!+)&%'+%)((('**(*)*))'#!#&*")"'''')+)$'!!++!+*)$!!$"!!&!$($%*(($(&&#!%#'&'+"&)$("&$$(+*'#)'))%)(+)&')+&#!('&$#)&*+%"$*$%)'"(#$%(*""&"&$+!&#'!+**)%*'!'*%'#'!#!*+'"!('(($)))"%")#!)+("*##"!")'#!*+!+)"$)*#'%#"#)")$)
@r7083
ATACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGC
+
$?>,GA><H*2H6>)5>0'$8?.62H7C,3#;H=5.@>>-859)8588:HB/H:DD&F9C>B5D%4D3#,@)EE#@$>>B9+
@r7084
ATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATG
+
2.#<8&7C@;D>,%/84B7A#$DF;@0$,H">@>#3/G0*G(H:3C7.0A$'+F#=?F@8!!+;E.$@7A7"'<?
@r7085
TGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACNCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCNCA
+
,13)?'0;C-/<$.'!62AGA.#+&5@1>$35=;+@G1(2=C,55<"5<#(75D'0*%D&E3A+&#<:G(0@E!4HH?F*6!'-(A(9)+%-'<2D83':8D;-.46<;@G4'&G0B,'"0/9#;&>,H;
@r7086
CCGGGTNAACGGCGCAGTNACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGNTGGCGTAATCCAGATTGTCCTGGGGA
+
E4$:91/(#>F1G4AD,)4F>GDF19F'-3-F437C(?!B:EA0B*6@G:1<.%,=H,#?'B$841),87$<E.<<(GC$%:2(C7-FE?4.G4@%3F7B7DEF18(.;59
@r7087
AGCAAATCGTNAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGGGCACTCNGTGGTGCTGCGGCCAGAATGCGGCGGNCCGTTNTCACGGTCATA
+
D09+.B"'=4DBE=5!.;:%=)8(5F+#B#8-GH:G?/AB##6$2.$<>-D-*$A>E;:,@8@>F9#3&1("2:)->B#&B=/.C@:6G.+C2C2C4:-<>(<<)D+A%<<5(#;,@.5H5:%77BGH8!1/>,4&%B,3G#(<1'BH1-
@r7088
CTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCA
+
/993DB<.3/0E&@,3GF.)(#?1!*@#69<9-9%#4!$!GF8:BH+-!D>
@r7089
CNAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCA
+
C5H$,=8)":$%81D9/>B(7F=-HG>G,*5B18F@6H&DE4!D4A+E"@(?%FD#3%-$7"'#$?@5DE54+="#E@A-"0;%3B:HA0B@&H(.4FH<B0,:%(C9#B>!9*!3@:=:#7A'-A#4>&'8+,D!1)/*!+%40-:&&:7'B+#,:$?3"#7AA0?=:HCFD:6?2FGG2*<'C*H=.B2A1"/.=9%.(73D+,,G34?.D*?993"(@8&?6,($C&6.:3A;'146?;(
@r7090
GACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCANTTGCCGTTTATCTCACCGGCGCTGNATACACGGGCGANGAGCTGGACAGCGATACCTGGCAGGCGNAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATCCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGG
+
03"/#.;G5=8:7(<?8.59,-6'+;7E@DFE2@)(C$'6"F9,0@=.;5%?9.8?)88;E<.11F7(16+?C@71<B5-6")75+E@&%0442*#D#&/.)DE-":>*C9=C*DBE60G3>>&=B:3)@>&#<5*EC75F1%<+3DH7GB8%81>G+%(&60C!0?=+H6'<+7C)+:$19.8G914D?"AH#!'((C=C%875%96C3',9F/1#E=-GE:=*41H7::'.'#<@)8>8/D&//-!!(:#/$1#!<1C@=28:0>HG7EE*G/+;)6>#;=::
@r7091
TCAGCGACTTCTGCGGTCAGGTGCTGCACCGCNGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCANCACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGGACNGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGC
+
"%)(%+%*&'""#'$&&'!"#*%!*(!'$+'"!*(%%(%!#+*&'%"!!!!+)%&+&($&&&(+)+)(&*'*"$!""!#**'))(#*&#)+)(%%*$$%(&**%&'&$%""(+'+')#+$*$+"!"#&$&'"!%%&"%&()#(&*!("#*+%#+*&(%$%$$'%%"))&+#)!&#!(&&)!*&($&'&*#!(#**(*!)"$#'!()#'+'&(!(")#'"&"""!(!#+*(%'"!***('+!*))#*"*))$"&!)"(%+!'#"(*'#&&)+"+)&)+#&&(&!!&*($++"+#+)+&&&)#)*!(#)#*$""!&+"+'&$$#'%%(!')%$'%'%$$(*%')))'*&&('&#"(
@r7092
NATATCTGGCGCTAAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAA
+
*(+(!&)+#+$(($$&&'$""'"+('#(%#%$$(&%&+"('$*&%!++!+++*%&%!*
@r7093
CAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCAT
+
FCA<?D=3&:H4D*&A!!28G34/;EH30G-=0%2F%:F-
@r7094
NNNTNNANTNGTGAGAATTTGTACCACCTCCCACCGACCAACTATGACTGTACGCCACTTTNCCTAGGACTACTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCNTNCCACTGTT
+
#$&"$!$(!"*%+()&!$"!&&)$(#'!)(*%!'$&'#)%)%(#+"(&+''$&'#"*$#)%%##$*&$"##'+"++++&'$('*'!(%'#))+$&("($&"&$'(!+##+*+"('*')+###+$
@r7095
GCTAAGGCATGTAATAATTCGTAATCTTTTAGCGGATTAGCGACCCATCGTCTTTCTGATTTAATAATAGGTGATTCAGTTAAATATGAAGG
+
H#G2,3(9(*+8AC1=4/@95EB.93A8F4AA$?2/*)5A)3<8!-$ED'%!!3#%0+"A=D.&.E7,5C+FB5=&'59G28&'E>BC"&6&
@r7096
CCTCATTACTTAGAGGGGTAACTCTTTCAGGAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCGTTTAATAGAAAAAGTGCTCCCGGATT
+
;-8/F;26;-F,&:!$*<&;#C#'F0B()0/HABH&9!8DD6-/<H2F,6H08@':5#0;G!-;?(,4D!2#<.<>A@B-.H$2/B9@H,4%7=1:6<%E-=E3%GA(C4.#7:<5=@5(?
@r7097
CGGTTATTGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGAG
+
02+9438>F7%3$9@)H2F>,.:(/A)@-GF8B5-2H!3-.?B5<921.3F?!04+FB(:9F9$1>/F21;,45C-@!GB%,>#('+)AA;G#-3/(-!5BCC@"A97$%$32<2/3-*:2;D"0==B!=H36G1!5;5+F.1=5D7F>>G%'
@r7098
TGCTGGATGANCGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACANCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAA
+
E;@"":H?+2--0H)C!3BGHH00-/;*%(5$AF8#+H5H"G;F?D);C,H(26E#''<9A7:3/>9"7$!:F(CAA2$H6!21>:4GAD&-#9)(84>@<9%:C7>"&BF01!':/H'-2%E=0;+<!G.37)G;<+82FG)
@r7099
AAAACCGTCTATGACGTGNCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATGCGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAANAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCNCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATNCATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTT
+
%+%#*"&"++%'!"$#%(!!*!)$%""**!""$%&#)*%**!!%#'#)&'*$('*)"#(+%*&!&+("+'(++&&#&(%)"!+%("$&#"%*#$*")'!#($'+##'+'')%!!'""("'&+)'%&"$&(&"'!")#!(+"""!"&"$$)&)(%!'!*&$!*##&%('$%#(*#"(")#%$)$##!))+$"$&#$'"*$!'$*++%*"+%$&&"($("#$$#))&%$!('!)$&$(&+&+"&!$#)$'#'&)!"'+'!(!*%&%%&%%$%%$'%*&"))($#*"*%%'$$#*&#(%%$**"(+(("&&!$'&&#!"*)(&&#$&+#!%)+($')%+#*(()&*"$+$%)+)'""%+$
@r7100
GGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGNGGCCC
+
!<7C/H&4<)/7)5).,,$@16)8&FD6:>9H:F?=G>(2610<<!5",?><4:C9#;E6&7=<(8,F574
@r7101
GCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAG
+
.%=:5/%1*2A$3".>@+@9-2&;<45+DB:42<>D%A6'5=/G)0,$#&+!HA7GB=
@r7102
CCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATNCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAAT
+
70:)/5>7/@1<;1?=>B"8%3870F*2.H68H35D-=$B3@<(.CA-.(487<!+@34$)34?6GD0D9/H@21"!,!&%:7H&%4!5D?@:#>'=%?%-075?E6A67F7D%0EC%+7F0#%A,/5E96D,3:,!%C-,'82(#;%42:0:.G'!46!.H
@r7103
NCACCNANCTCTGACTCTCTTTGCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTTGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGC
+
"(("'("!(+"#'")"!&!'*'*)"+*('&!#*$!!#'&$+*+$&"'('**$%*++%!*#&(#&*!&)&$*%!$#&+&'()#+!($'"("*%*&(#+#'(($&'"$&"%+#"&"$#%)*&!%%#"'%+&*'
@r7104
CACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAATGAGAGGCGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGNGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGNAAGGATTTGCTGTACTGCGTGA
+
;765)=<8!0DE!9='B-HG!!(E*:-)F8*6)8$9!9&G4;H!2@-'D7(-6HA=.E/#9#4>6!A#6@/0.E;F(-=1"&)'-AH90(686DB9H40&$;DB1&6:C+631$68(/..*FF?B%6/.5-?"B+7A+#,C6$F@*?GE%%-".%@,5*B(+@=88E?G8;
@r7105
AATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGC
+
/,:$$#)>B'0DA/!HHHG-95-.8/(%HE'E>?(&=<*<%:0==&D7010A;"&)3"$;B:
@r7106
AGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAA
+
,C,-F$3EB!91D;%B';H8>%(.A#;+$H%<7?*GA*4B+(
@r7107
GAANNTCAGACACAGATGCGTGATGGTGGNCTGTTCTCCGGAGGTGGACGATGTAGACCTTC
+
'$&!!$+!(()%#'+!+"+"!'!(+(!#')%()"#'&"&$+!*!+"#%*)%&#'"+!*!*%"
@r7108
TGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGNTCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGG
+
7*A9@,;7,@>0E%'CB57(#G?>78H'A0#52(<9=&5D:G/(9<0>@F%C.$186-;0D>4%%$6;1,&5A&7=23@4FG8+$()?G8G(F#<6)%9-#F2573*>7)/>F:#%531.684G9:,"*7,%/4+B8F:.*!*.B$:?=(E0H0A,
@r7109
NNANCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTNTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATC
+
%#!"+!')"(*'&!!''%)!&+)%($'*&%%"#&#"&%%'%!!*$"$+('($*("(#$$'*)%(#))(+%()#+#()!!$!%(%#)'&!()"*')$$**#!$&""%
@r7110
TCGGNACTGNTGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGCGCCGCTGACAACTGCACCTGAT
+
)$$*+&#'&$!"'%$'!*#(%+&+*"*%"+#'+)%+)%'%%("*!%!+'(#)(('(+'#%)!$'$*#+#
@r7111
GGCGACAGCCTGACTGCNCAGGAGGCACTNGCGACGCTGGCATTATCCGGTGATGATGACGG
+
54@3,'A63:"!D"#=#1.'-;?"G4,=//$A9#%)F#<294D%-4#)88:F>B6.)7*5D3
@r7112
CTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTANCTCTTCCGCATAAACGCNTCCATCAGCGTTTATAGTTGAAAAAA
+
7.8=$?2="<</"0=(1&G/>:<3?+<C?62H;<!!@<?56F14%0,C"!H6(F3F'7A36'D&(,.F3F'+%#!E#G
@r7113
ATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCA
+
(>4F!'%:-:)2-.G7C-A&6#?,>2,,5-9497"5*E)7-7F.14#90)7=<+C
@r7114
NCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCAGAGTCTTATCCGTGGAAATCANACGCGCACTACTGGCTG
+
"&=2$B5%-63.*%B7F#!#F5$A2G2FCC;-(-888>,;80F&,-GC4)9#83)02C1HF,!)(E+.7:C,#B9;2/C,9)-"/+-H<!)6D#(H11
@r7115
TCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGC
+
#/9%*#("!<<C81?!=+'5!HH%@8&4B<*?$?#5166(C3>.8&H+AA,?B:2>A'5;.0.2-C?:)F0<%6"=6?;47=*'614>
@r7116
ACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCNGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTNTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTG
+
+()%'!$&#*&+&$$(!(&!)%+$#")'(($$*%!#%#&#$+#""&###&*((!*#'&+&+$+))'#""&#+%!'&*)(+*!!!"(()#$'(&'+*)*"$"('!*('+)&##%)%#%()('"&"+*(%#$+)!$$*+%#"#''&&*)($+)!!'($('&)#%)+&$"!&&+%%"&")!"&*#'$&!$('"$!#*
@r7117
GAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTT
+
%=E4==98.3/''+6F@2<;8<$1F&A()D*<75;.!D:E92?94:9=9/>&B"6(0@><81;!9!CHAGDHA0:C@1=AH41"-,H8.8)!&5-!
@r7118
ACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCNTTGATTTTTATCAATAGTCGTAGTCGTACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAANGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAG
+
8;F%/G&F!.7?7'>1A#G%&DF-:&('AF,(-'($H#E5)?#6%5)&:(""9>".GHF@B#G';5BHD,HH)0+B3="?B!#$E7-1=4D5:H;48=D5F+9"=5@G69&1BH@E#(%>+--EG*023DE8#'/,)A3354<=+#)F&-6$$)9H+9,&D%!BH+&/=@#B?G8926$B'=A79#'C51E#AB7,G'81@9A01E*G-E5'60<F*@E<(?*6=$0G,HF5B(=2,)3GFE/:(#+138,4H-C1G/DG#$9??>9D@460F)A76+BD<'F++F;D*465;FD%>>,DCD$=F62""$-<5(:?1=<-+F5')93?/'DE':;'@0<#220
@r7119
GCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGA
+
'7513D.>715#4BH;>2D"7,E*9/C?5:/81,3/,3B#=F'$;0-5<3G='<88F,,,28.(#0</62,,-0@
@r7120
TNNCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGA
+
%%!2+#:2A);#*"6)/D=?"+'&&*5<C/,CE.,5AH8)3>-3.,#E2'<DA0D4<@;C/0"B983&.82!3D9/-$<=&97H%CC!E;@B
@r7121
TCCCTGGTAGCAAGCCGNTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCNGATTTAT
+
.=$BC*;HC@+.)@(#?7='H%7607+!':)%E50;-'CB<!><'66FF$E$!!0$9#=EGH5!75HD$!2DC)@,(9&4;$B)/#?6="'1C,<
@r7122
AGATTTTGCATAAAAAACAGACTACATAATACTGTAAAACACA
+
2)F7:-E67'F!-A$B!!-B,4@A:B"'%:$#"-/284E7>*D
@r7123
TAAGTGGGATANTTTCGTGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGG
+
!"*('!(%)''!'#)$"'()+*+'(%)'"#&$!!*!*+$*"'#**&('&(!!&(#'*)!!#'"+(''&&(&&!'')*
@r7124
GGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTNTATTCCANNCATAGGTTTTACGCAGAATGGCA
+
0AG0@CDH!'39@78/.!3!C3B.3&+AB"=0A,8F75'9A#'64-77:=8E0<D//=66F%0=5?63%3!
@r7125
GACTGTCCCACATTNGAGAGTATGGGTATATGACATCGATAGTTAT
+
'"$)"%*&%)(+$'+()%#*#%*'")&(+(*))&!("(+&#+*)*$
@r7126
TATGGTCACCGGGNTGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTNACGNCCGTTTTCTGGATGCGGTGAAATTC
+
52C89H6#D;E0B4FD>?8!&%1&1(#"05*=$)!-E$C.(,93#0$A,&1866"E&B."C.+(3:!2:1C/,*@F06")H3>!7HB<$:9:E2;@>
@r7127
CGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGATGACGGTTTCNAACC
+
:&(G,H"+8,.?#"-@2?$"+D&.AD$3DE=-E0@4C()>F.3,#3<%?)433B.3=C%&;*1$7D@'A-6:6C.:A7
@r7128
GCGNGTANAGGATGGNGCTGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGNCGCTGCCCGTGCGGCACTGCATGACTTGAT
+
(*&**"'&*'*()#%!'(!$$#+$')$&)!!))(*)$%&+$)))'$*"*%+$$'$)()%$+(*&$#*)$'#$!''#*$#')#!((!$#')(")!#)$!)$*'%+(&%(!&!*$$"$+&&%%"%+'"""
@r7129
CAGAGTNCNAATANTANCNCNCNGACCTGCGAAATAGCAGAAGTGAG
+
)(!'%'!'&*)#%$!*"$"$#!#+$$&""&&*")!$($!#("*%&*'
@r7130
ACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACA
+
24?88?<C*74--<#->$@6*1F?'7CB"E#!#%2B,&>%FCDFB($)7B('$E3*)?9/<(6;$0F2.!
@r7131
AAGCATTGACTACTATGTTAATCTCAGTCCATGTCGGTGACAAATTAAG
+
;1"@7-(!A012"*:"8,1@5)?"<)#57/G178EG9*."+2"73)77/
@r7132
TNAAGCNGAAGACACTCATAAATTACATGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAANTGCGGCAATGCTCAATGGATA
+
0()/*/A;/:-49D)G)5?%85!!:@/$!!-1#@(B-B3:.0;).=B+B/!CE7/+"AAC06;54:2D@$%?)<G$&!=,A((=(-0+4G5(E;4&'50E3$'<%12F6-5%+1<E5?
@r7133
CGCCTCCCGGGGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATG
+
FF/2.7GHF&0?7D=@=D?/E5F-+H!&,)<7#AB-&;.01/H%.C::5C<"$&1.C';C@:8-.!+(F5"-.+D#?#91@,45;A0E85%3.!>C/D:(1>';'BD95'311H=+?-,"4AA?!C-',9@A.!*4=#H$
@r7134
CTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGNCTGCATGAATGGCCTTGTTGATCGNGCTTTNATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCNCATTGCATAATCTTTC
+
5E:@::#F',-&6:@-#:(<B,@8GB(<:DA37E6$F!CB3.1(-3,*/):"*<!0H82)396+@,H":6@)B?/1.A0.+!5G4AC"3%F>*3E31'0=G;!56?D97+GHE/<!F/?A5!:+%:<-+):;).FG-<0'=>
@r7135
ATTGATGCCGGACTGGCTGATGAACTTGATAACAGCACCGATGCGATC
+
6?"564('.96,)!15+-H41G9%<&6HB,C=E=$@;!<>3!97(*HE
@r7136
TNATGCTNTNGTNNCNTNNAGCCTANTNTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCTACGGANGGTGATGCCGAGAACTTTA
+
!""*(&'*!&$&#!"!%"$")'($*")#+&"$)+&#(&%&!#+'"!!($)#"(+)"$*&'$+!%#+'#%*!&+'&"#'*$"!#""'"!#%)'&
@r7137
GTGCGTCCGCATCCTGAATGCAGCCATAGGTTCGCAGACCGCGTGCCTGAGTGTTCCCNAGCA
+
=<FGEE*5!!>12.4551H8GA3&#H9(,1*5$,B3+E%0?#16&5A0*!(3HG1FH@AB)</
@r7138
NNGNGTNNTTTATTGGTGAGGATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCANCGACCCCCCATTCAAGAACA
+
$!*()("%(&+'%$&(%'*+&('!'%#"++&%#+#&%&)+!"$%+(%'!&&'"(+((+!!'%%''(!"&*$%#!%!(()(($''
@r7139
TNNTATGACAGCCCGCCGAAACCGGTGGGCNTTTTTGTGGGGTGAATATGGCAGTAAAGAT
+
)"!++!+$%&()$)(''%!+*++#+!$&$&*)*+&+$+&*$&'$!)!"+$#"&((!$$#(!
@r7140
CCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCTTGGCGCGCATCTGCCTTTACGGGGATTTA
+
CA5*4!!!!&/CH8)7CE=E%)1")@-E;3))H3=HC.;=%!FC-',0F,+D4F4:.*B').9@.?"8(85*$<H7
@r7141
NGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGNGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGCATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGNAAAACATGACCTGTTGGCCGCCATTCTNGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGC
+
%8A+E(=#65&*%3E8%89A6#6""6,C*F=8&7@)>A8C/G>+0)7H1,/90-/":-0;"7)A,%H)%2A/:E04F%G-&H8'+F+E8@#<:.()3FG.A*BC.;8-@!D5,-8+&8%%H+D<;<F1$.7$AH7"7G3:@C#/F8&1=@B"1:.*9=$<A.7>38-6/<%!><@;!;@H?"49A.H@"74.*9E.##77.$(396H<<:@B=>EH2'%13B?./",0874"5/+.46725F<2!?"-.88DH94$/,-*A-)G(EBE=A/A.$!7<6:8"#.A3,$1E(#,7-'DE<ED58/:CG((D>>0;:FA0#45A9,?,"?E5-$9E#5?D::).D4A-9>?./(1.?F4!E
@r7142
GTGGCTTCCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAANTTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTG
+
>(9*#B<H'.9=G&74'-!H*B-4$2."3;%?'/A2'4036$$1D!)#4;5'(7E%2,%;4@<.%9E>:?>3F.+%C.=F8+),G43=DE'0
@r7143
GGTTGGNGGTCAATGGGTTCNGGATGCAGGTGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTG
+
:>>&$BGA7).CC9!C*&$<(6-3>''3&)2($A<:.6CB9G7/$&<D3"?&58$C-!#%5+0=C/%%6/1;6%!5.@9'!#&82#76CD<E>
@r7144
ACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGC
+
/5#."1=#9&G"&'4>+9'>)G+4$%;43G,=!$*@H?HCG?G!AFBAC20/67&3/3'3-=.$/,G?F(;C759.&<<1?E;EB3B7'18
@r7145
AACGGGCANTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGANAAAGGAAACGACANAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGCCGCCGCCCATCCGTCNGAAGTCC
+
H*3#!2*#)4.0:+$0'@<0+.GA/46$69/B$+0-7C!#1+;<>,"9)1#%6+3CDBG!G,!A1B%7>9E>)7#152>2;H;(2/(D+%,:>:->/'A;,!G?75'*9062*3D>+2;13C/-:(95$'89+AH1HDA=<;:62#;!E7%3?=D"82<&(C.64%:1(%BD**@@%8(3.11%H)0(E4AA%4>7@7D;=2#;&;=?F$A;@6F,?/G@:%--%+)89/"@":,>GF*"802"")+24>E"9-33>';.;@.:<E4)*'C:#8?013/8:(01".!CB#4&
@r7146
NCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAANTCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAANGTCTGACAGTTCAGCAAGAT
+
$+@',5!C8%?5>C.C9A:<#!;;0*AA<@=;48A<BH;45D%.8)!'7='H3D(58/@@>:D2F5CGD@"(.0@%4H0!9&9)?3?H,'');?@E,3DE';GH%?,H5D:<BE/9;$/>-;2.F'-E?%?@3<
@r7147
CCATCCTGTTCNTGAGACAATACAGCACGTCCGCTNGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGTCCCTGCATCAGGTCGTNGCCAGACGGAACGATATC
+
*D-D"9?G(.4:7,B!@??=/4<D(4C-E>"4#:0A8+9&$F,/6A,4H0/.9=*+#$*%%!G68.A,6A):1/C).+%<!<#;<>)H!F&&(?&3<H2=G9.3?3G"<F%/C>C#BF4/7!B15,6!)AG8>+!=2$+G><:,5.'6F081&)H8.A,(0:"*GCE7$6
@r7148
AAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGC
+
/88HC=&/;1D61-&."H@A'3234%:$77:A1*?>*6*B@&3#$?0,@@)6A@&HA/2%GC%D;%;!G=016
@r7149
CCNATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTNCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGNCTCAATATCCGGACGGATAATAT
+
H48G!D+6G9G/?5@$@B>E9+.0"!709.>3/!G!,<CC3FB85(!5&)<&;3C24#$8;56E(,F83.@EF(>D?0+;83//7+8,&76?;%3"2"!)='E(,4#>4?H$<1'4)F."?93#)$0?)'/,!'&<8?>?@F89EB>$"=8(-F@6%-B+D*/.@:HFG
@r7150
CCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCNAGCTCACTCTCAANGGTGGCGGCATACATCGCCTTCC
+
GFE+:65G<!!49,-0@(2:=2/H-G;"<8=2!3B5*6(</F-%#A%20F:7#-C;-7)+,$@D"&:;E);<35!DD95-,&1.
@r7151
TGCCATGCTGCCCGGTGTACNTACATAACCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCT
+
$<-9)6.('*+"'367AA@"8!#1D%2/18DB/F:FE<<;$BE<03)5#464;H$,E9FA./.:9)./52@@#D#D<9E:+9-B32$&*0287
@r7152
CANNTGNAACGCCACGGGGCCTGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCG
+
&*#!*&%((*&'+)('%)++"("$"()$)""#((!+(&)*&"%+*$)!'((!)'+!)#%$*'#**+*"$%#(*!$%+*)+!"*('(+)##+'
@r7153
AGANANTNCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATC
+
(#'&$)*")#+!)!&%&')"(&'$%$+(((!()$%%%$#$**$+(&#+*!#((&!%
@r7154
CGTCTCTTTTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGTCTTATCTCTCACAAATTCCGCG
+
.3'(B/7*DG0>36;!,+1C!/$F:<85D&<=8C86%>H>1E009#)&'"<0:G:?2<%>4HA7?>!
@r7155
TCACATNATATTTACTATCTAGCNACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTATCAAGAAACACGCATCTTATAGAAACGTCCTATTTGAAATCAAGAGACATCACATTTC
+
:*E.6E,'05H'4D2#1687FBA,09EAEA/42#A?GG!A(6=HB"?6E-7'5:FF6H52H,@C,G9712CA!/H01/*6#3+5B&A%D0?-;5/7'%%<BB<A!;F>&97-CA5$7:+:@*6B*G6H@D7?2D9C8@>38C@A'50*32=*6%(AF!0/6D1
@r7156
TGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAG
+
7'/3D'2C;;B2;%("%;$(.5F4?'F726G>,F<2,H(7)''."!C0%A=F/7@"848?E1
@r7157
AAGNATCATATNCAGTTACCGAGATGTTCCGGTAGTAGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTNCTCAAAGTCTNACAGTTCAGCAAGATATCTGATNCCAGGCTTTGGCT
+
#"$&))"))#&&)+'%*&%+$'%!"$##!)$#%$$(*'*)'#(("*'*!!!'%#*+(**!(*(%!(%%)'+!'&%#(%!)(*('(($*'$("*++#(!&'%!"+)#"%)*("'%'+$)+"*#$%*'#!++
@r7158
AAGGAGTTAGCTGATGCTANAGCTGANAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTC
+
:"%''9F+)><.",,0=AD/=&H6*;EE4G,7-&'B4DB-H:D"C:$G++=#4>@'27B/A';B
@r7159
TTCGNAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTC
+
C9$F2&;%$-;%&?6:!5;@GB;786&<E=H/:%5HA85*+#"*70:4+<"/!4:H/)DC@@--%3(;*A?E/C7$&-GAA"22>C$!2E.8G.*)20'&F&&1.7>E@!9B9G7'HA#%7(>$@8>F-,FH)61D?/1+C!>D!:)B!G;"E:8/@6DA
@r7160
GAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCAACTG
+
:,H@=3%"0'1:?-4+A2D-3GH$%$/#C!%36#G@.EC1*4#C1A!9D";
@r7161
CATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAATATTCGATCAAGTGCGAAAAGATTTAGACGGTGAATTTTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAG
+
:F1(0'H##7A@6!.F?A%?"E<AFA;C-.@,@.$*(95F(A;/F",=!&'CA#+"(6@4?5%8)!%E5D@,H+0,>9DD;8CF#>5E%5$.7)9@C?0HAD"9H?!+G804"1%D?@!"1!:(2H7,(:+9<&7?"(/!6
@r7162
TATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGNTGCCGCCATTGCCGG
+
8=C*;$A=61D&$'D/*!.>;7D:/@A);>'9%9(.B42'D/./<3E*.%.+B+E,)%3&-68+*+:HB?(;:")
@r7163
TTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAAACACGACATAATGCAGGCCTTCACGCTTNAA
+
,"/8:'37A#2#-75H-'HA?<F&2!:<*C(:C:6'5?B&CEBC;.@!%%HH*2EHA2F=<+=3.(50-/*9.?;+($.?#G6DF.:0C.FE
@r7164
TNAGATANAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTNTTTGGCGATATATT
+
&!()#(#!%+)%*#)%()#++'!(*"$+$&!#%'&"*#!&)&+%$!&'&((+"")%+&**!'%'#+*%"+)&)!#)")'!!(#'('*('''+($(!#$)(#%$(!%++&(#+&"
@r7165
ATCATTATTTGATNTNAATTTTGTCCCACTCNCTGCCTCTGTCATCACNATNCTGTGATGCCATGGTG
+
A"%<21!2*HDD(64%<@BD0A?0.$3$65F3HC?(3'H7,BE*?%18%"+'$04@5.<8(04;H:97
@r7166
CCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCG
+
43*.64@AG)&<&!#>'0&)B5?%04?,4;<?<7,%2,1>(//+6-C=8H..%AC?
@r7167
GTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGACGGGTTACCTGCAGCCAGCGGTGCCGGTGCCNCCTGCATCAGACGATC
+
.H*G>-=&F)0B.?A'+BG-E2<@G+520E0.0(H?91$#5;6EDF!7<(B6+#-D>0?7-F=%F&174.%'.@)HA=GCE-EG-B1%05+F*-4A05+C+&6<3+.(/G2A?-+4/"@.5;
@r7168
AAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCT
+
,7<CG%>2?*A'@.8=$07D7)B@/BDG?#+4E1!F@1C:6.E;FA(':?!A">/CG6"$*1%*+;?;!7$%
@r7169
NTCNNGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTNTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAA
+
''$$(+#'(+'#&$"*%"!'!($#))$$*$&!#+$"*"'#)*$$'&'()%%$*)+(&'*+*$')!$!$#'$#!!*&)%&%**"('#%$&(*+#%*'**+##)'*
@r7170
NNNCANGCTNNCNGGGAGNNNTGCCAGNAACCGNGNGAACANACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTNGGC
+
!'")%#"(&""&!)((&#"$"$&&*&(')**"&&$%&*%)%!+!"$#()*%##%$+(($'+)"%'#$'+&#$++"!)!""++"&#")(+)")+'#")*%"&$+$('%'#&!
@r7171
CGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCNCGATGCAAAATACACGAAGGAGTTAGC
+
+(#%$'(*)***#$*$"!*!+%!'"*+(&!*(("%+!'&'%"#'%(!$%!++(%%%!#*)&+(+%"%!&*$*+
@r7172
GAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATATCAATATNATATGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATATGGAATAATATATGNTTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATTGGAATTGTTTTGATGTAACCACATACTTCCTGCCT
+
DC16$HG5"(H('3$9%9//%?>3,7F#BF75HC00@9.$-:=8"=G%6/C9$8E/#1B273$#DB=!0=5!-#A'"@87.3%$0@2!&(4>%&AG4<')H"91:<:3/#B&C>4C3.#03/9=(5B;.>*8?$"+86@'9+@+$952HA/-">7-,>A@@4*4'D7<F9#>D!$8>91>E4*2;A!+3AF*81BB5.!A*$?&B+.G-,?.B6-).<53G12)$G."?-#(G?HD=/,HA;9D'C??<5+062'+G52$;:4CFB1'+(,2*>:$;+G4+2.-3=41+<-3
@r7173
TTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTANAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTNCTTAGGTGAAAGCATTGACTACTATGTT
+
G2AA)!8$!17-/B;>7,@!C@:#BC<@=*,$?)7?>,EB6/7.,9;;*<A;(01?B44=&;EA92=C,;0:%:943?6*$67*!!%*$*=4*C4'3!)*C'?EBC-:016*/%GE:+H-.*4$9'#A:>!"->31.B&A81-'>===DA:/3@8;
@r7174
GCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACNACATCCGTGAGGTGAATGNGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTT
+
DA#8E):@:8%-@CG@$*;);<B-HC<<!'?13=7*56>&:A;"*$)2#1&8=31)H?--/5AGC/!%@A/-*0-F=7@)>'1>E%G$&%>9,)A<B:5&53FFE:B+B21?/!4A09D32
@r7175
NCNGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGC
+
&+(<""2-B<).%;;?7#?,4<>G'#.H5+$'':H:9C7!,9E4)B!#F0'+B<E)";6.7&G4.7('BF/;@>&CB/3H5'=$&$>92!=0%D3H.8)BD@F&3$6<D8=!E-)/H50(;%%2#*(=5F)6HFC-*@.E8-F89(8%8=2@(>8?7'E)18G
@r7176
GCNTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGC
+
"'+!)#+!($"*+*'%!&!*$#)$'*('("%"&)!*))*"('("$'(&$!(
@r7177
TCTTTTCATCTCACTACCACAACGAGCGAATTAACCCANCG
+
@$F27B.*5"0;HB->A&2E-0*;G=88$00'('>";49;&
@r7178
AACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCGCAGGGACATNGCCACCAGAAACGCG
+
F5,>6*2=#>(G0,8/7*@.7?HB5&.8H%C5#77%<$+$.)+&="$A>E!*;'H$,.A0(,0A5A7%'<#=,-C0
@r7179
GTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCC
+
5,:3(@'"6GD50?%:#F%/*@5=+<-6H<9183&760;)-%%676/-:7@*3#!+=<=H-AD)'A(="52'%
@r7180
CCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATTGTAAATTTAGCATCCGCCCATTCAACGGCGGTCTG
+
#.G17F?!@A@-;22"##<:!?((?:C6?C+,1-84H/G>/(1>:G"$>,-4B6H#F&3@C*$<6"7/?&0)C)=A)CA2!&,;F+AF:F<*(!E9*D02/'++"B234B7.>8
@r7181
NCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTA
+
#1@/%:-60+(D%./C#A83/5H29+.E)@(@=82$9C.0;8+D>6/
@r7182
AAGCCTCACAATATANTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGAT
+
7+38",8**97-77%A02G75!5=:91=;!,3(@B="")@<FB95!D/5B)-ED2>8>&).=:.&5'*/E-7
@r7183
GTATCTGGGACGGATCGTTTAAACCGGCATACAGCTACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGG
+
@4:<+"C71)0#?<$6:A15)*;'@?HC;40$A-!/<C1;"(46!24<-F3A?+2>'88+2=5D8:0E.G#+AG9'/9B3:?A5+,:6F?
@r7184
GCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCANCCATCAACGCCCACCACCGGAACGATGC
+
G91-0/;DF--36#5G<>3:!2!6F$E=-1C$/-0C,D(1'1H,*/)<51!-<6:&,&0(22>B>.,D!(,0,-/H@#12:
@r7185
TGTTGTTCTGCGGGTTCTGTTCTTCGNTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGNTATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGT
+
(@%?CG035;3B/D*2G(*$6B0B*3&32>$#2"B)-5HF+&H2&2G0A#57"+107*2>=D:@H/6#"8HB/0&/-;%!0F)5=9,/#=!3GB,;>""D;+D=+&)+"#4(C@7*?:*8!H+?E6E4%3@7:$C2!$630-F>97)&&0E#6>/'4*9H<3)&G/5G6'&'B@(3&+0,F,F?$C<3;'DE")E*>G!+;1B&<>E-4=?<6E6B
@r7186
GNATATGTTTTNCNCCNNTGNNNNTCNGTAGNNTNNCNACGNAANNNNNTNGNANNNNT
+
#$##!$$$$##!$!$$"$"""!"!#!"#"!$$!"##!!!$##$"$!"!#!""$$#$!##
@r7187
GATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCNGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCA
+
C>,H/'E&6!<:61.$/,H(#'A0<+?@),F&)5$?G@;A"=D.9=?474:"&?@8,2H/E=2BGG0*8B.7/0'H=/F="*E1+6D%*;E"44C8(4=):#$5$)&@7C*48+CA02-3,*5,D+2/63(";!73#%*''85A:/"'-D)+G.8&7=6:/?7A7C(#'G%D7F<2%H8#
@r7188
ACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGT
+
C:=.4=!%>CA451=.?>"42"4('07;F@(!CE6$;/>4>
@r7189
TATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTT
+
*24,86><>FD1/$(61/%=FB"A3:&8$42>!078G/.:@=5*!!#/1H="
@r7190
AGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGA
+
<4)<:<+-=7*7#A91F6D1*<,,>GC4&43,B$*"(=>;C3F$*+84>.:'#H!0;->(":,%-8&.FBH,1$A>18+;'FA9H1%%3B#)2(:-<)6D6==*D//B:A
@r7191
GGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGG
+
;&'(F-)*)8*FE*'?-5;+2@)59/&&!/;,D=7;0H;1-=
@r7192
AGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTCGCTGTAATTNTTCTATTTCTGA
+
78$7.09?8,:=0G-%>,4F(C"03*/+C*10"%$.69)H.'6G$D/.?</F'8G?=H<=A
@r7193
CGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATTTTAATGAGCAGTGCAGATAGAGTTGCCCATATCGAAGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTAGGTTTCTGTTTTAACAAC
+
&)+!)"((&"&#)!!*"()$*"$$"()%*(&#&&')+#$)"+&!'$#!'%+*#$+'+(##"(!)+")!++#"*#*$#!*$(*!#+%)&%++$*#$+&&$!"%*(*'#''$&+!%$!!(""$)+'!(*(%#)$(&$%(!)##+!+&#$*%&+"))#%"+$'")!#$"'+#%+"*"+!#$#"+&#$))&%!*+""!(##%!$!('+#$&"#(&&+$$)*+('"(#%+&$$%((&++"'#%)'''(*&$&)&!'!%+"!&&""*"&%)"&+'+'+
@r7194
TTATNGTAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCNCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTNGTCCAAACAT
+
$)(("&+)$)&%(&!#&(#)$*"'*%)*")'!"*"*%)$))'*&%!)$#+(&'*'"!(+%&)*)**!#'#&)+)+!$)!)&+"()!)+"*)(+$+#&#)+)'$&#!&!''&++*+*#()&''+$&!!!"$+'&!)#*$(+"'
@r7195
NATCANANGCAGANAGGTCTGCAAAATGTAATNCCGAAACAGTTCGCAGGTAATAGTTANAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTNGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAG
+
#&')*&)%'((&&!)(&+&++#&!%!"+#"+""''#%&%(')%#$&!#%)%"%%"++$'&&))''$*'+'++#)((%*$''%'(')'$+&)*""#*!#$+")&%)"+%)&$'"&%"'"$$)(*!%*#**')*+!')")!%'!"''(&#))!*+'($#(*#+'!)(+*+%'$#%+$#)#+%#%!)$('*%(($%'"&%"%#+$$+"*'%!!%())'(+%$(+
@r7196
GATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCC
+
1"%<!(DAD.D9:2C08D08G,HD6C+#*3*H>G&<->#E#(/<4%GG!F=D$'"'<AD/*
@r7197
CANNGGTGCTGATACCGGCATANTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCC
+
*!"+*&!)$+*(&+)(($()$'*'#*'#$+''+#+'$+($*%#)%%)!!'"&%+$*))&+)*%*&##"#(
@r7198
CGCATTTTTATTGCTGTGTCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATNAATCCCTGCACTGTTNGTTAATACGCTTGA
+
-6BH@<$%1F5;EC2*E#9>';E9C>$81EA0?B#6-E:,1"5=)'H3GC#5<A6)02"!..)"-FC&(9'(7<)@G=;/C.FD?.("4BE';<A&$"5A<%?A
@r7199
GCTNNNACNCNTAAGNTTTCAGCGAATGTCTCAATATCCGGAC
+
#$(&#$((!(*%"'(#*!"%$#+%+"%!#%%&%&*()*(()#(
@r7200
NGAACTTCCCGGACCCTTTTTGCTCGAGAGCGATGTTAATTTGTTCAATCATTTGGNTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGN
+
)7'@*>(7$7GH2/#!$C38*.EB#)/040**46:6)8F05%6<)8.9;$8,#-@$(C?@9DAC<F2-'.82((2H42F(=B'423A-C+A:FHBAC1>=05*4'3&+"E$"6B)$D(D)-1G8<7;65413-1<#1@3<4&#,:"<,:$>11B3#B
@r7201
ATTACCTATGAAATGTGAGGNCGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCNGGACCACCCTGTG
+
0E<)F(;#)-#;,,@G)9(2EG2=$(#?%"+??5G:(1;G4047E<B5D"05DHB53"-#7!:"/=$6;3!D8F&<(3
@r7202
TTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCTA
+
H;3570$218*?97*41?<;!=:&E?'AA?%)5<$-H+1+!*!(5H3,637.;4B!5A/&F;@74*+@#&!+"<,<!'%$*+<9C"2%4C%@#1(/4@;C8&4
@r7203
GCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATAC
+
<<E&""+0-3%;D<F()+0):+?<5H86.-D@5(%0%:04+3D34#G
@r7204
CAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGG
+
>C=$DA+8E!44598#AH<;*87F>/><7'AC=2"/9&%$.1H&>-FF)7D)C58C#=5H@@9F'.;/>BB!+-4$=1#0%$;%C6D7@6(E/%0HH7#'!B',@8$!+)(6112G))9,9&<+G)F?3-=;!710?/77=:7?5)H8<1EBG"3H/B?>
@r7205
ACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCC
+
>-"D8/):6=3:2-?$+(!.-3H//28;A=)B9,<F65<>/0?3:)03=&:948+6"59)*8&$,>6*$*(A$+D98+F4".(DE;?F.&'<0&G14)5'';E
@r7206
ATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACNAGCTCGCTGACGNTTGGCAGTCC
+
A"!-:-6@0--49(AC"($!689*1?5;/?<;-%<HG!51;1:4:&17*F*AA47>4A!%4@H+/43:9?G(95$H)"D:2@+>
@r7207
CGNCCCTTTCNGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCC
+
##"+*)#'"!&!+(!&%&)&+!""!#%"%'#&!+"*'(##"$")#*'!#$'#)()&)%!$*$$+%(%&#&(
@r7208
CTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGNGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGC
+
5E8*8GB201@)D$1!>D'0-!1+G+!03.E</-"DFH)',B8A,@'EDA<%0)E/!7(3&H-G+-4F!#-%&,(+=:FGD,H:$39D@33@-#-BC:7',EH:"/6-)?H-C((@=;;@;8F70.0HE;$0%AE#3@0=GE)!050;/-=F879#F?1)6,*5AH%F/F7$F)::&C@)83?H!"4;H6H"H",6#&9@7;/%9B7%1;C".D$@">'%<>%@(0B/*,:*-/&.G6E)11E
@r7209
GTGGCGGGTTATGATGAACNTGCTGCTTTTGATGATGATATTGNACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCNGGNCAAAGTCCATCCGTGGCT
+
5"E&GG:*?#;*>)(80(=7:9E65DF<'7C/2=A$0?/*1;(4B6<:BD1G##>>H8:?*+2B1*"C3EB0:<(;<9F%6)''>FHG+A?0/6=:8:@FH.F10G#8/,G-$=,3D"
@r7210
GCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTNTAAACTCCTTGCAATGTATG
+
C*+.*DB2?D4?#251>>+A>!*<F>G,&3!':;&"(6<?&7/>-6A&)#2&$G&>*5E>#>>4
@r7211
AATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGA
+
3(/69)>$1/.+30A<&.3H5C&#):D6"A'-FAE6D5&;&@.HA66=%;-H09DF?"*4>;(2)#'D*(;:GF(/%E7<2"C'E(/0:)7D!/0$=9@&@H+E-:/6.-
@r7212
TGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGAAAGAGGATGGTG
+
30CHB*-6.B=6-).A#;<8&<1GC>F)BC#B3#*CDE&?2G"E'
@r7213
CNCACTACCCGGCTGCGCTGATCCCACCTCANTTTCATGTCCGGTCAGCACATTTTCCCGG
+
&##(#*)+*)$))+%"'+%!!!*))""''++**&"+$!$!&&$)")*)+("#+)'%"+*%+
@r7214
GAAACGGGCCGCNATTGATGCGAAANGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATNGCGATANTCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGNACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGNGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAA
+
"@A%-H/5#2$<49?&A984,>(?*6F%HAD"3G'6*%%!9!8;$/,F!9=D#85<:&8C>G26;8/$2*E",)7@H97?6613,#7!"A?@(=7#E3+45"18(4&2.2>7/*+E(<E2+,:*,2H':;?6-5/4,:0A1(*0F-@#F>A$;'8:(,#+":"B??0A<6:<=!E(:45%%:BD+>=)%:).26<(A25FA?7@7*=6+-A@?"*<&%9/G**1#(7)C&:3#52AD=FH.'+(;'BD<8))**)<C,3@(2BH@2EH5"FC//703G>>!1B9D01)7-<>8;<;0;--5:'3E0!<G60F/F4.20>5@<.$68*/BC,-/@%8C89?!+9H5D,!"4F51:5?'>##4/E8F2.;&>7-C-D"*
@r7215
AATGCAATCCCGAAACAGNTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTT
+
<07?H2C2+6%6B.>/@H,3(=H516&='H0!7<#-<$)8;+:8A"0D(4/-4#E.<52C:%
@r7216
AGAACAGGCCACCATCACGCATCTGTGTNTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGAC
+
D>-"!E4"'14-=9%#<A#9;:7#5+'>$*#?FA.F8H%C;A*C1);HG+F'E*D9?1F!(0'9)08$1+?H,H'B$3"--,:D1>E5<H.0;2/G9"C$>+@>B().9$7+/3A#()='6@($5@E)4H6H-":-4E)H*<&)HB>D%?*!3H4
@r7217
TNGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTT
+
!'C8GE#9F<'&'0=0??70*5!A).)B3;3706CF*C/*/$1'4C*!)
@r7218
CAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGG
+
1#7?6%0/7D5<-)9:0@,=DC6$'E280*</C-D7'*#A,8=3.9&'C601)$>$D2"-EB!1:+/>9D@*-#69)F6#(,,0<6:+7@H$1,!.:%&?1#4?>%4AB+#3'E,@10!84$DE4D8**5/16983:0=DG"%8&B14G!C.(8F60:9
@r7219
GACCGTGGCCCTTTTCAGCCTGGCNCTTTCCTTTACCAGTTTCCGGCGTA
+
'12>B72E6.$-!@%7:A@;G-9>E'FGE@C4FA4:A$%>=F*79)(@9"
@r7220
NGTNNTTNAATNAANGCNAGANCCGNNNCTATAAAATCCGCTTCCCGAACGNCACGGTCGATGTGTTCC
+
!*!)")&#&($&"'&%"$)$$$'$&##!&&+&%*'*'#+')''!)')*$*++#(!#+#$"+*!&"%$#'
@r7221
CGGCTGNTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCNCCATACGCGC
+
&(%)&+!!))*+))%!$"+$!!('%*$!$%%%"%$""+$%&+!%(+"#("'')"(($'$#!"%''!++!*$""#(($+!!#*!&(
@r7222
AAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCNCGGA
+
()-!80AFD3F#4?=D6C)>ECF'G80+),0.)4@;$"E6(8"D
@r7223
GTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTG
+
3F:88#+364933"?+,;76&C6':)B;(A9$D8>3*0&?1%&*''034H'"D'#;"F7&!@C&#<:78";#
@r7224
TCTCCAGCNCAGCACCGTAATTACTGTGAGCCCTCATGACGCTGATGG
+
;>3F52(,B12B+?)4,<FAB<80(F@8H<)%9("G00=-5B74A85B
@r7225
TTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAGATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGA
+
@5&'375%.!)831>96<-&6/99$HF;$51:+;52?0?$66)+D(?%=C'*>D4A)226:8%!&%)A9/=F*A0.1A+<C9@DE6;-4=C84H067@4$06=FC9(#7EHA'8*B/3<@0<0(/1.%CB/@*GA0"2?$F%)C8G3;@:3H-&
@r7226
GAAGTTCGCAGAATCNTATGTGTAGAAAATTAAACAAACCCT
+
C-*A<669+-!+)A#.1A!F.+--C.$&F0,@37*("A>@90
@r7227
TCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCA
+
,GE(,BE60;H(G,6$1&?C518GE.CD817G5-F&?@**6%2GC()86G13):((0'C,8G
@r7228
CTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCT
+
:/7(EA@=4318'A;8>(:,:!-1HDF%($85->H++5!-758<>@<&6"1EB'.=40*/3
@r7229
NCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGA
+
")(&,*9FD$@>D$)70?.61*77>#3D"A641'00(F1.6$$HG4#*G,%!(:BF><3=3D(2>*4#;#"&-045&
@r7230
TANGGTGGCCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGAAAGGGCTGCATGATAAATGTCGTTAGTTTCTC
+
))!$+(&%$&&&*+"')(*%!&#''+%"(#(&#)#%$&%+*&&%!%!+'%)&()$&++'&#*'%!"+((#'$$(($'%"!$(#'&%'
@r7231
ATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCNCGGCTTCATCCGGNTTCTCTGAGCCCACCGTGTACACCAC
+
:H&9?C5.E=-2-@9;">'-->)G9"%4G52;<6@',"C#3,=:26"1@$@(#'A=00C>*5%?8A<<#$.+>3!F+<>(D>/
@r7232
CAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATANTCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACN
+
,>3%H"4@';8-,D&.;0(074(G<-F!C/,A"*'(0$)08%,!#?>6;(DH2?A1@=/>B"C9%6@1(D9C<115&?+2*9##@8-#@.522(*64B>)>)-97549&7497347#-($<A!4616':-,*"(HGG6/.5#;):F36E+B4
@r7233
CCGGTGGCTACGACGTCGTGCGAAGANAACANGGTGATTGACCANAATCGAAGTTACGAACAAGAAAGC
+
)?:97"3.!F'2D<*%1C%B)@"12=:BH>:"4&)8#3H7E:+@'>E>H!;+.+*&GB$<%&/%AC(H0
@r7234
GCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAAT
+
%*/<49$;H%C"7&7H:#&+30"2;!@#A=H77D0>$D7/D:=G;"@99,=@+EC"3G5:9='>$4F'7C1+;)G!1E67"$A:>,2:>2A
@r7235
CTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGC
+
:0.("(-H2%@FA1("$@F/B:4A3H"DH0G4&@(%>85-H.6?,+F-B'@=F%4
@r7236
AGCGATACCGAAGCGTCACGGCTGAAANATACCGAAGAGGCGCA
+
@33GA@(H)=?/+<.8H!DE%)'F2(&9%C#2"$/2')$B@?A<
@r7237
GGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATA
+
:>;9***A.+)5*5"C9<.>:HDG?95)**<902$?3-G@.)C(<=
@r7238
CGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACA
+
4))<!*A)(0!=@,=%/;&!&2?2?#=3.4E%4?-!"9788537;,DEC'>H&317G=;:?D;:>.@&(C'8.3!8=1(73CD,8D0)6!,3H:;CEE3#<>7=+-6<<9D<%29G4G
@r7239
GTGACNGNAACCGCCTTGAACTGAAATGCCCGTTTACCTCCCG
+
$)(&'#($$'#&(*+%*)(#$%&(""*''$)!&+$)%)"!!*!
@r7240
TTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCATGCCGCCAGCG
+
F.:?E8@H65@G/<+0ED#:CGB"5;6$*'<H-(+'>?D=A@DE<>3
@r7241
ATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACG
+
"?4B"&>32/A@4?!G::C?4&E&'##$F8"(4FB%);D-@7C.E/G;9B?83)2833%695!,1B".H>*7"B1F,!.$*G6
@r7242
GTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTT
+
"+$&"''+#!")"$("$!(*)$*(###'%(')(&$*"#"!*&+!+$(!!$#%)$"(+"&(%'%((!&&)*""$$"!#
@r7243
TCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACN
+
?+B>68AA02>>-0'**H))7.+7/!3GB>2AFGH$3-/*G>E$$.))+-)4,0:
@r7244
ANTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACT
+
*#GH6/G;'&+/A.;,<EA9@%3A?;=04;7()=%&FA5/9(A')(8
@r7245
CGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGC
+
568('8"BB#8,/!=6-=>F<;;&'&"!$0-7'1**=A$81-8AEEH13$F><32"GE&AB!=%
@r7246
TAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCNGGTAATCTGGAACCGCGAACGAATCAGCACCTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCNTACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATA
+
-@!15?>>3D8EAE"4D$@-8=<@,A#,.1,#=-!G/F'C"8/$/<?>F65;8&.*:-3A#.<*?9>AA=.:D*6D4.68C9&1)#7DCA/7'/A$E("G<&,F)"!+",*:B#A4C+F0(78A*37%22D#*72?=1/>.-A8"/8C-<7A-=B#@$8>86CD31==E-A+:<?)113=#2,,:5F#!1A0.&((!/(H=(:/?<+1)B%15FA<H$9>%B8668DF&?+:"FB@7
@r7247
ACTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAACACAA
+
%<FG#H6+)-620!0?,#'G6152=<6!E?,;C'52B224>F1>-0H1!D:H.'
@r7248
CTGTATCCATGAAAACGTATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTT
+
8-,H(!2;,"G6?@0-@)#5?EA97+9BF42.<3)F:D.>?=$7%31$%D+6(5=0,D/'A9!G&1G:>EE1D54A('6'9(?5,",'9:3:(38H42E#:CH-81EE+>D+)H33.E'%9D;@23;?3A*=*!1'!
@r7249
TTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGC
+
(.93,)"62E)3.41(52?479.D.<8D(FF6(./>-FF(B1%72%;28&8!(66B9:
@r7250
TCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCANGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCCCTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTC
+
9!;1FG('B4$+=+/;CG%-"F#;)A%>,<%%$&B%.*8,D58G#2B<=2EE%@#51C$9D-D%E)$3?,3<1BH*0E%D80*89/2'D.3@37>10#+1:'>/1B(>(+48B;"6"8-"*34:A/4;<DC?C1<3G55$*C:-&G4;ED@='*65=@:2D%/06>>#/40+H<349"E:1;$2B%9"/0A=F#H-G41=17!)5A9"/EA24D=<-#:%G&H4-?
@r7251
TGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTCCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCT
+
>&B'A(FF359+@3&85!H7B>!:,.(@2B6H3>5'"A6;82+471:&83#?7@.F'#G6!:<014;)14=;;/34*B:639701=.)%4F?-$C3(,?"874#=62A0#G"B4!0>?G$&@0H/@!G'7
@r7252
CATTGCAGGCGGCGAACGANGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAA
+
B9?3&)2<FC?C%<1(B;8H!CAA2,B.+GC.77(0=$$CF$*171FF"(@7@CF9<)CE"5&!F/F
@r7253
TGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGA
+
;2'19!7D&*F?3>/9H9)7+*;*+,#GH2"1%4%!)383(95&/
@r7254
CTCTTAGCTGTTGTGCAGATCTAAAAAATCCCGAAACCGTTATGCAGGCTCTAANTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTNCGATGGTTGGA
+
0C/;1@&/-..5(>)?&36B$5A1+#&58/8'31#&"B*=307@!6*$,(5.E)5268>,E)B<:A;1>0&9E*?G,2"(,,C.07(8F-&244"6G$1E?:G5+@F%CHG(%!<8
@r7255
TTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCT
+
4,;(89GA!B4/4+?0AG=A'$C0>:E)=<4>8H<:C)!7D00CH=CEH%6<H3.$8#BA
@r7256
AANANNNNNTNCTCNCNGANNTAAGNNNCGAGNNTNCGNTNAT
+
"$#!"!##$"#$!#"$"$!"$#"#!"####"#$"!!!#"$$$#
@r7257
CACCTNCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGNGGCTGTGGAGCAGCGCCACAANCTCACCCTGCATTTCTGCCTGCANCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATANTCACGCAGGGGAAATATC
+
@>$;<,*B)!,B&1",<,D,)-,<$?)G??F7BF772)58/3!F-$D735&$2:6!#2:9$;-DH-EG52>887A#=6%0<<!&:0"5&?7=$DEE04@3@7H;,3'':A=;6!':;6?#A%5-CC;%),$22+6H9!,H7(/G;C.9&+C-485))01;>/D
@r7258
GAGCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAG
+
"*!&*$+#!#)")%$%#''*#(!(%%!$"&($#(&*)#!")'**+&&)#%(
@r7259
ATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAA
+
/"/4$H7#?#0'/?16-GG&C@G?7"A53":E)8B)C/5G4"F</!4);&&DG?
@r7260
GCTTCATAATCCTTTTTCNCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATA
+
<+<F%(&.E10E.&;4GA'6'/;)BD5*;<;">9/+D?%E"(,EA"<E)0;2B(EECH=B!G;;F?360,9!@B>:=?"(F../63/B'9=.;0&/C,%E37*&
@r7261
GGCTGAGTGAGGCCGANCGGCGGCTGCAGGTGCAGAGTGATNTGCCGTCGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGT
+
8C"C#E9,%?:F-92;78+E*9;,$GG>9;FG96#G$&H=,D"<EA=8H>@9-9H&B7(-+7"7?0"/:B,2!-<A&"*:5GD<9)=+FG9-@@D!.@5(!7=8F!C>*2*#:%A.H"(H?8:3?>H
@r7262
GTNNGCNTNNNCCANCGNTNNNNGAGCNNTNNGNGCCGAGANNANNNNANNCGCNNNNNNGNNNCNATGTGNAGTNTNNNACGNCGATNANNNANNCTATNNTNANTGANNGCATTGCCGNTCNCNGNTTTACNTACCNTGTNCANNCTNNGGTGTNNANCCANTCNATGGNCNAANAGNTGTNTNCNNGNANNAGTCCNNCTNGCNNCGTTGNTCATCTCCTATTACGCNNNNTTNCCNCNCNGANNTT
+
##!!$"$"$"$""$!$!"$""$#$#$!!$$"##"$!##"!#""$$#"!$"#$!"!$#"!###!"#!$!"$$!$!#$$!"#$$"!$#$$!$!!$#!!!$!#""#$!"$"#!""#$$"$#"!!#$#"!$!$"$#$$####"##$$$$"$$"!"""$"!$$#!##!!#$$##"$!$!!#!#!#"##"$"$!"$!$$##"#$#!!!""$$#$"!!$#"##!!#!""#"!!$"$"##"$"#!"$"$#!!$$#!$$
@r7263
GCGGCNTTAATGCCTTCGCGCCGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTG
+
+$#"%*'#)%#)$)'$%+'!)+!++$)(#)%"'')!!#*!"%%(%&#$*(((#+$)!'"+)#)!)$)'"+$&"#+!"%%$''#**#+$''%$#
@r7264
ATTATAAATTCTTATGGTCCGTGGTTGTTCACTCATTNTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTG
+
=5?E5#(5&<<.*?;?;#%%B()*018.4=#A#?EE/E6DH!2"FD33,.D0-;583<H'#"D/B*,B;@H;G=73?1.24(,-5H=167847
@r7265
GGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCT
+
FF>;,.CGC+!<G&>'?3@+C=!=E53!H8@-,E9H>>,49,=4/
@r7266
NANCTGGANCTATCGCGGTGACGAGTGCGGTAGCGGTCGGGCTGTCGCNGATGAATATGACCAGCCAACGTCCGATATGACGAAGGATAAN
+
#+"$%+&"(#$*#'#!&"%!!&$$()+$+#'!$'"%*(%(&)+"%*")(!#'##!%%&#*!$*#**(#++##)*()*%'%&%%)!(%)())
@r7267
TGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACNGCCATAATGCCGTTGAGGTGAACTGGAGTGAC
+
3D2+)?2-,++++!--,%6B5/>=38&.%<H71='D)3>#&0&2*%=EB6</?%!G=2-;*?B6$#!C86")+;,/:1%"14?348"2GB@.)>%!A,-@1=.DD+C%2-@13G&/+"@!/6*D:+2"-370@6C9F%+E;*F5AHB'H0A#,F.$6&@H(+
@r7268
NACTTNCCCGGCGAGGCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATNACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAANNTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGNAGCGAGGCCTGTATC
+
*;@*?%?C/5329!#3$3#F*%'!97(#52"G;.3.).:.1&$0.+(6A:9-3-4%6%;%'E,;5(?7,E/=*8')D2H8D>-5#0?)B3F'0;G4(7F*31'!7F#<G-><'AE>0.E+#)2!H".1*%07FB9E'1?,?CD,(@AHC/:;?4@D973D57/%/0**!$.A;)%$-/2)13"8&#-B+4&8?F6A='!&/:#?/F+%,.?DD:/$(!$=<HB2G*%*@<?.1"+"<01?HG.*EDG<037G+84)H29!&@3'?5C%?&)B=<;
@r7269
TCGGAGNGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACNAGAGGCCACG
+
=$G0F4;'B>%/+7$6!0'<#4D32H-EE.H4,7#.,<F?F,@$-C14>"DH%*5-FF!3#A+'4BF"*>,0(G;40%#:;-:7!2B&A;,$23&'B'<CF;D&*CB--$$>F7B951?17
@r7270
TTAGCATCAGCTAACTCCTTCGTGTATNTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCTTT
+
958C9&G1=$"=H6'H9>;D#+)7H,<4#1?3D.$FC;2&E6><"CE(.,'@1!3>;D47*B>%$#?8>,G4D6:*<?>/",&:CA:0#G.+9GE)3);#%A0>@#E2FB
@r7271
TCNNATCCGCTTTCACGAAGGTAATGTGTAAAAGGCCGCAGCGTAACTATTACTNATGAATTCAGGACAGACAGTG
+
$'!"("'+(%")"'")#*+&###'"!"((#$&$(+*+&'!&!*'!%%('%*+#!*(&!'"&!#!'!%!)**("%+'
@r7272
TGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCTGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGA
+
B!=%F7HBH@1-4+.;3?#?/.HA/50D8',!5!(FA3.F=(/$/00&"&;;4.C"FC:@&@@9;9"D'?E-"7G2"7(,#E%$&7)BEB<1+*@;:81=.&%*A1%@
@r7273
GAGATTCTGGCCGTTACGCCACCAGTCATNCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTG
+
C9D@"-+#+6+4';-?0(#+,D-A5@1(+CC,'%H1E."@&7"H$#?F:"@*<9%A)*!@/5)?!.??-0(;B+87?/><,/H%*0/="
@r7274
CCGACATGCACGGGCAAAACGTCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGTCAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTNGCTGGGCGGCGATGACGCCTGTACGCA
+
=;)A>%F56$:B911'&B&-?0G7*-,%'9C')5>?F8$G!"':=F!4DE:C/GA@2E*9A5($(2'9C(2:7H02@?=CG)2$)<(FF.;+<$2:)-B8HB;(@)0(DAC,<%''EE#(5'E;>%"A@5$%H!3D,G6;"A8%:+$656F2;AC.E1)'-#51.,9DA20EC:?5=
@r7275
CNCATCGTCACCCATTGGAATGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGT
+
#$2BE?C!B:5*C@@>4.=:-1HD">>E!):/.0FH#"'%)9"1)&B1&@)'0**&%;*-)(9C&9=9F6BE=%%+#;$=>>73C@=B
@r7276
CCGGCACATAGCAGTACTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAAGANCCGCACTATCGGAAGTTCCCCAGCC
+
-E7F4-..6#&!,?-H6@'<<6H-:C>/3;&7'24H+F,G%3?086@HF"*FF!03(;@8;(9$/B=#C(B0"%+F9'3-'314D';-F'.#>F4F$4H=%;@&::3.2*0<D16+HF,9#+%-<3G#4()/$FFG+F*)@G=:1
@r7277
CGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTNTCT
+
D?A74>(6,#CG9C0.5!=C+:F!E:;,-GHCG',3/*'G
@r7278
AACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGANGCTGGTAT
+
C&$;2"*F551=?$H/;@.5!"$F,9,"/#?2="537,2A#22=+9"(4-9EE%6-H:@E7E)A-=17=+8=7-05F!4<@=>E4>-:EG*83!=F)8DG;;.,,$(=><$"@4&!!%/1D)?8
@r7279
AATGAAAAAACTACCTCTTCCAGCNAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATNTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCANAA
+
:E$-);?#$GAD*2&6B=1H'C?1D=%#!7?-#*22.0=)0+&)A?9G8?+<H'H7$2B5HF8E5)&C0@8C&;+31)F<E-"/B$':;28+;<0E,#>9E+3<5#-26,4@CG/(&"!514A
@r7280
NGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGA
+
"&(:@!=.9'?-?(F@+75>FD%2=25:EF9#):;(2D6!(G
@r7281
TTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCC
+
&3<-E2&6*ED-E<*-%3,"(?1*@B<HA.(<%$D/:1+5H7;E,)#!E4A#//F#)@<9)
@r7282
GANATCTTTCATTAGTCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAA
+
*++&")$)%#%!'+#$*(#$!(%*+!)!)()'!')""!$+%)$#&%#)+%$*)"("#'!
@r7283
TTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAANAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGAATGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTANACATTCTGCAATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGT
+
-B%;(:?7;:=D8#(&G@&8$A@E/$-4HG?8#3.+,"C81%,+C:?3%A:$-E.,>=45&/:2>-4/&':5;&6C?8-36@$15@'6'@B>H"?-1/E@'>6&@%;3!3AG=&G<79)&*0C=?%";E=B?:2)-A+3,F1.!+(59*#;;53,CE=5,:CB!5;A?2**>)+-:A7024H(9.2B-*,B-6#E,+<G3(>0!?$65./!2B#95
@r7284
AATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTA
+
42)B>"#;6>E6+/CFF87AG=D<@3/5&2GCD5"H,@=A<>->H1<.2#,)*1,?B+EB1H
@r7285
TCTGAAANTAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTN
+
-07'8.G%D&#!@G=D*##*#+467?/39>7!.B@2*'03+=BA<*-G"!.2.A!<(H".&'55?6:7%7F*>&*>$7-!DD:9>#?=>H?
@r7286
CTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGT
+
-20/:F2@(!<=D=F"G$592&C5#>88C96&5%"#G;>8C4BC+2&$%.##<'@4&6'$+'.*CH
@r7287
TCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGANCAGCAACCATTACAGGAAGTTTATCCACAGNTATAGGAACCAGCACACAGGGTANTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACTTGCGCATACAGTTGGTATTG
+
1*(;??$C+7/.>76<;B*+@"=2"$3.1H5&H(%))4B5B4C@3**),&"89B?#'),*.)),%!?A&,2G"@;&=B-;G9'!105,-FB@9HD7EE/1"AHG3)*+"#9(<<9+/<7.>;#G3>GH)8B.$&D+!$>D*<#,/G%2@C1%$5,.#94,E"F&,6F=>/5+1B+*8&78H#8G&'),&+HA%8,5#5H?1AB:>,E0%"A/&*D..G0!-'39&'H1-
@r7288
TCCGAGAGGCAATAGCTGAAGGCCATCTAACAACAAACNATGTCGCTGCCACTCGCGC
+
:39G?*4C<?F/4D'<4G#6'>.$5(8/;"05-:)!%:$%>F#0)B"0-#4.6?)/*G
@r7289
CACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGNAGGGGAAAT
+
('<.(!)&:*-#B;&H(;1?$E==!@3-0G;=0C5!!/:),:?.#,"=A5*5B)9B3B-'FA>F&CA<?62,>,%3(++:+-A8+!9+7C4;+#-*"$6!;=:=;DA/=E,./%5/*.A>-<D%0F#$,7F,+8-64
@r7290
TTAATACAGCATTTANTACAGAGCCNTGTNTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTG
+
7.F3(69C8A>%3B84B9>HEH&9>$+,;4599:'(9=.:<90;6CG68#3A'F,:D%F-+F>/%&B4%.FDCD+".F.>//7#2'5;BD33*/6->CC9?,-)9BG9F#55++&!%)9-4581"9,2:+0#@8D03B<8947/26G,08#==*A5*G.H;EG/8
@r7291
GAATATTATCAAGCAGCAAGGCGGCATGTATGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAANGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGG
+
-)@;:@B";!0+:"+10*)'<1<F.#*0B(<&6*1C&F$)@<,&'HBHG;8.'H&/")0''@<2G-AE3;&9A!;G8*/(8&4!HH+0".B?#&;F2<C27##B=3*'-&3F=69(9'55F-=+7>+<4.=1E03""<F@5,/&-2
@r7292
CGGCTCAGTCATCGCCCAAGCTAGCNCTATCTGGGCATCGGGGAGGAAGAAGCCCGTG
+
2G20;"C$5+0*F#4@55$+>$H-2#74)%?@4)=&%7./?4/8A?1E<2;?E$A#$!
@r7293
TATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAG
+
3'74".*:<'"4@8$"@'.3,70D%/A;:?>0;&3A'7(,?31D*A)F4A,'"3&E8##?=B?='A-+*7-0-15@%)="9?)6F)',*04!E3A.//',=@1@4(!.,@#&H%61*@@H0H/=CG+/EHB':1E"<"&(D183A$2.D?3';">67977'!5!);:+=5((561(-0,(%:3,0CA.4D@4@
@r7294
ATTTTGGTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGT
+
4#F)<1H!/8<+0;>8HB441(.-'F91814?EC?:%#E,@3*F2FFE$!&(:C@,>69:49!&46CE",C28=$'81%6-;@2&&F7'"0+/*,BD?4*($/.1386'-%9G#F#"!9&'D9B,"',F8H5/>!*
@r7295
CCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAAGGGAATTTCGCCGCAGCGGGCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGNCTGCTTAAGCAGAAT
+
6<1!%,)89C-1/<+2G05FCC64.E,4A8E&(FH:83A42((8>91;>/5,9@=2>FC*GE;,F!*)&4D6!<A-8,!*2!-";39:.1/)C'6"3A>#3B42EB6H?+040.&$*D7&/6F&,;A0/(8/<@G9&(?8*?=/43'"*2@;E4GB9!*;-$:?B'(*8>3&;#=;
@r7296
TATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGT
+
9E-&+4;2A=8@B/09'=@'.B@1A"DA0#5#'9;863''$(8$7?.;.7*8,1D6B@&F.D,<=*'E"2
@r7297
CAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCAC
+
C,!F87@)A?<FB<<.;C:8/=-H70?2FF@"7H&52/6@05+EA-+B87<E:.1<;>-=)H)363:@6:>>D8/B:
@r7298
NACACTGCTTTCACGCTGGCGCCGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCA
+
"0C#;2/D.#:>67@/:!+$D-0H@:#EE-".,&4#/?&".D1H?</=(%%E,H>+<0A75G(G0:"/1/$<32/4D
@r7299
GCCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGNATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGT
+
!>A-(-822;B>AE#<999-(&96G%-85+;8+&80@B5C-@1>A!)0.,$$HF=9AE>=@?H7E)#"8<F)C-*"70D2E'4*GB/>2!0<$'H83'-$
@r7300
CAGTCCGGCTTCTATCAGCATCAGCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCNGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCAN
+
B-#9>D:6!5)>55G$1E8%"1>?G/0=#71('!B@?9D4.G9D(',$:@:9AH$@>+@5,0C.)8$!!-,0H/!>;5#%@>&GA&DB.'GE1=03&1(,FGC0?=F*<>4>;35$&>G949=@H!?9>F:G#&"?G&$EF!F;
@r7301
CTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACNGTTTCTTTACATAAACAT
+
G-#A>!&-46H&C;'CH8#3993;C"E7)!A..AC7;C.!83B1&,C#@)8G3C(@30D6*?A?*7B2<
@r7302
AGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGATCCGGAAGTTAACGCTAAAGC
+
(.:8D1"<4/%>4#G6):+%7%%8AGH.:<1*D!&7H==*!DD#D%'C!'6$95(+?*EF.(7@>82,8"'.F-D?!4E8$4/2@B&1
@r7303
TGATTGCACCAATCATTCCATNCAAAATTGTTGTTTTACCACACCCATT
+
95D,-"@4?B#8HBG4<E9+*'34F(G6BDF*=1@/>,-%8@)GE1$9%
@r7304
ATTACATCCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCACAACTGGCAGACGACATGGA
+
596-840D-#D8429G>/E:B;9!3C0,+.H<C5C--F%8*4@!FE>2(&1)E'='C!A2(D6%BF67?4?C!)BB>3BF&E#B7:*F.(*G6B&5"
@r7305
ACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCA
+
B/76,F5/CA!:C54@B/#)(A2D46'=(9#%+=<",*7&+'):F4>
@r7306
CAGCTTCACGCTGGCGTGGATGCCTGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGA
+
E:<-:>F2$;=*9=F&<G!9-C$/$E*EG"1+<5G6<!DE?8B3,B:17;D62(-#H12!(!18&44.8$.H
@r7307
CGGTAGGCATCCCACCAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGA
+
99;@'DC&;/=E;%#:2B=B*647C7'..*>DG<4A/,/D'4?F140=11.8)>?&BC92%#16?&587G;:A#=C
@r7308
TGCCTGTTTCTCTGCGCGACGATCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGC
+
"G9/%-='8(%3-$(C/*"=,F0;8D0"5H3(2/2,)F"+$=?>HBG%%)3-0:03-?<2-B)%8-D9@3#6!1.7>'F%2FG<&H8B09(2+H;FB271.5*3..119;*B%+29=H,!?).//8'C5G
@r7309
GGTAACCTGNCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAA
+
566*3=8<F-!0$AD<?93,H=5<(263C)>$(''3,0$60?@*,:4"6:E)D;=C.("?#%>7;6>"&AG:-/7?;C(9
@r7310
ATCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTNACAGTAATTACGGTGCTGCGCTGGA
+
%.C,6;D?A0A='4,6!"<G'?@BC>)+8H,3E87,+':2%)%4(82.%%;E/E68H@/6@$,;%C#/8@<&<2'F&2C8&&F4
@r7311
ATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTC
+
.FC(H-=)7-G49=.?+>"D*6"?9"E.>+7')EH(G<*(7!<=-%5DF?2?/&C95:3(1.=7'2D'H2*>4$@!>/F<+AG<B
@r7312
AATTCCATCCTGTTCATGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCNGACGGAACGATATCTGATGGCCACGNGATCGGCGCACCTG
+
C,,",G5#9C5;F5EG&0"."%A,8%%+HDB,">H3H3=&>6B*./C;F<F=(?A<#.;E.@B50#)G&:(8;2?"F!05=1&"+7780EAC-'1>88H*$)1';2+56?$:5#F/37*B@5FGC')A<0G9+@?5GE.(,,$%,C/!0%<)@;(8&,/@(#4;D8$)9/G.&@;%%(@1E/@H:5C-?G7A'%0+3<+9
@r7313
GAATTACGCTCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGANGTTTCTGTGCTGGCTGGAAGAGGCCATCGNTCGGCGCGTGGTGACGT
+
+!#&+$'$*#)*!(+&*$"!!*)'+&!%'+#'&!$!"!'$")*"'$"''"'(%"%&##!%%*!+"+"+(!!+$)+$%!$$'*!!!+)")*$#")%"(!'&&"'&!$&((#*&**'!")'*(#!%""&#)$%!"+!$#$+%*&%"#))#*(!%+&"
@r7314
CATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTANTGTTCTTGCGG
+
+B=&-F3H(*,"*H61.&6**?G&%H$5-$'&>&0.+6C%D)G*'81*&>4!A.9#F
@r7315
CTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACA
+
C!<$+%=#(F1D@-H-9E7!(>A81E2A?1B5B5.8%06%21)?$C=84EB9?C,&!-4=G</-2":A/>/)B4"!6$::+4)!,:9'9#%*3!>+BFD/9,:(H"0'%F3=#-9
@r7316
CTNTGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGAC
+
)'&"'B$;H(,E*0::<9(<>60D+<'EG4#3D&C?A@$D"GC">#8G;'F2
@r7317
AGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCGAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCANTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACC
+
EB?&;G#=+-3%.B/:3@>AD5(<H3A<>2G5(&F=#>9'.%'F0+3#+)=$?D'#F@*&71,>21).*00AE"/3AFH!,*@"*(;<6B*:'>-'6?%4;BC;!F(!'-E@E?=?GB.<'F.4;DD(!ED7';G5.!'6$;(0#A#)$B@!?G$;F6CB.@F1%,0A$=.5A92:</0'5A%B@-131?:
@r7318
CTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTAC
+
5*4D;HB(B#@@B0#:A:?!@7EE-;%3C4!)<*(!F!#A5)7!'0(*(9F?D@:2=5H(5,+-1GB%8/F"/C+
@r7319
TGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTNTCTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACNAACAGGGGTGT
+
*=.HFC$1C=CF:)F)(C=H!+>@)F/1>>C@%1<%DDG=?0E.">B)-5#1>7#.'<D(H$C796G,=#(F8HC'5+C4<3//7C$0;(C*@+F(.7**B0:$8<4?%0&B#-F-:"%<*"<,<88#-)@H#("%0%.9=@!=0"4.2=H<-70
@r7320
CTNGNACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGNGATTAGCATCGTCACAGCGCGATATGCTCCGCTTGCTGGCANCATTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTC
+
!%!%+!)*%)+"&%&"+"$*$**+!))#((+)+#+"&'#())*()())%&+#%"%++$)!!%*'!+%*+"#()"((%#"(+&*+!!**)($!%$#&*!'(*'""&##&*#'""'"'&"$%*("$(")))'(")"'+$$'&"%''!+$""")
@r7321
ATNNGTNTGCACNTCTTTCCCTGCCCGTCGCTTTTGCTCCCTTAGCCAGAGCAAATATGCT
+
&!%%&*#"%%%%'%$"')$&(+)#$&'++%"'"'!)**#)&#(*!$&))&$")*$$&%+"#
@r7322
ACATTTCAGCAATACAGCGAANATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCC
+
@-$&C;8/$H)"@,&=(5$(=B>2;2A"$?=.@:&C/H-'>6)438>!C;2(F-=7#@-H@7F(:7@)7?F3G)H"=7C:0())GB+2>+:(,%5<*11@#%4:94B$2A-EAH)D20D=D6/05??+-'86*(C1;=)))!@4&&8@EFE97(E3H';CA42#("4G+,C3?H&,B09FE9D.;=.C-.#)%.5+>E&<+4G'#A4*3<,?>,:-=#4?<1,&DH
@r7323
CGGCAACGGCCTTGAACTGAAATGCCCGTTNACCTCCCGGGATTTCNTGAAGTTCCGGCTNGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAG
+
;&)F@F!4D,"/A;5HEE?$++D9:+6AE7%B=971B6209=9">3'"F<7%3A78)4=)<=8):>4!GE'B!<9-'08F%B==#()#?6CA@EDA6$'GC#;/$(
@r7324
TCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAG
+
=*6?)D@+$%-)/(4FE6=5E*C:(6&72A;)$2-1;,1/?$0&9=?&*?@&$%G6'C"@G
@r7325
ATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCNCAGTTCACCGACGTGGCCACGCAGCTTGCNGGCGGGCAAAGTCCGTGGCTGANCCTGCTGCAACAGGGGGGGCAGGTG
+
#+%'!'&#!$+!'!)$#)(!'#&!#&)##''(!!)"'%!'"*$!!""")()%"#&"%&&"&+$'#%"*!")!'!$)+*+(!'&!++%!!)$'%#&$$$$)#"#*%%)+&)$!("%+#"%"+!#*&'*!(%+"("*"&*(%"$***#")("!*+$*%)$(!)")$$"$$(*!#&$$&+"!"'*#'&$#%%+!*("%($(""!*)&#')!+(+"()&
@r7326
CAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAACCTGGGTATTGTNTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTNGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGT
+
534#=#0+FD<E9%!*E3*C:$,%D'0"1H+$"-)B017:</"02?+"=+F,8>#/6*6H5&F&GCC(/53(%AD;D/8D->:::**5E=9$H4C6@C*$%'.?A"2BGEE5+9%%<+*-)91G4@#!5=4/C9*&#'(DE)D219:;7*>9"09"8B*C83":&$3+7+'H*"("6(E$1()8*1$25/E4>4!E37G-&99%$@*@-%3@$-5+A((1E*(>5#.3+H9#-,@3=<<7B*..*&;,%&AB9B5$;0-&>:)FF!C(1(H*<&H18(>G$$>/*AEA.E!-
@r7327
GGANCGNGGAAANNCGNAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAA
+
!*)*"'$&'&((""%++#+*')"*%%(&*+#($(+$$*"%'++)"#$!"#((!&!!(&)($++&+!*#$#)(+$$&#)(+(*))
@r7328
CTCTACACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCC
+
E<C+6BH.09.,-)*CD!(+?#!27D*2?<4*@4?!(3+;2%;2D6>?,1,BG/"$B$(=/
@r7329
AGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAG
+
8*HC$*29%)5.,/;#F?=-';;"#(<6;=3+D***++*:*(!0(34-G92+/<6H!-
@r7330
CTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTACTCACTGCCGGT
+
>)BD(48)/H(:#,;+,H(1(;'=$=0,",/@/!5'9=@+AAD,9*C&;'C%;():BG=7)#;=$=-1:,H+5#!!1B02F#'7D8H2B9B%&":(#CAF'8?FE?!75<(HG!>0-+;D24>D80(:*.(,7=,!"C#&/3@<A)$A
@r7331
CCTNTTNCCNCANNGNCNNTTAATATATCGCNAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTG
+
%'("$*(!&#&!!"'&%##+"$'%%&&'!+"("(#$$"%+)++'%&*&"(##%!(%*'"##$$!**)$!!**'%)+$))#$$)!(*(+"!&()!&!$&)('$(++(+&'(!%''$$!$*+&($'***")&()((
@r7332
GATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTAC
+
9!;/;820/B5/+@D3C;1:>.FE;,A/"5GC>;'@"''<E6B/-E&90%4%;+9
@r7333
GTTACTTAGATATTGGCCTTGGCTTTATCCCAATATTATATG
+
5F%:"05!69@%<'>E6*=8:8->CF!A544G<7$)+./E1H
@r7334
CGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTGGTCACGCATGTTCTGCATGATGATGCGAC
+
6D$39:39%'#)/91D.H'&141?;'=,D);!%.><4B"3=2<!C2(<&;+%E4//G@*CFC:FH.DB2,9#4++%58:?A%60D4;7120'83*B"34('%869
@r7335
ANNAAAGCCAGTGATNCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTT
+
%%!&$*(+#+)!!#!%!()%''("!$*+(!&*($(+$*!$*&+'()*&)''*+&"%*!)*")#'++&$"*(+%*$##(+
@r7336
CANCTGNTCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAACAACGCACTCTCGATTCGTAGAGCCTCGTTG
+
%!"*"*#)+$#%)"#+)'*&&(*'$%"*$(&$!$'$(!$*+")$""##)"!)$%"+&#)&(%))#%+!%#%'(#*(#'#&"(&+#%#&!+(%()!+&()))!#*'
@r7337
GGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTT
+
&+*$+$**$)$+#!%'$#$(*+*)+!%)%'"!'%(')%)&"+!*$(")$"++%!+#+%++!)#&('(%'))*!%$"!&$#$$!&+&++##!&&(*')%"%$!+$+*%+&(*%$!
@r7338
GCTCAGGTCGCGGCCCTTGNGACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCNCTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGG
+
:A2'+D.@&#G+67D45C01/@!D-(=><4,)<%-;/4/AA6)B=C--=75';:8<28&=#+9"1!5(C"-"*3$B%4+A15-)<#0!0.!<HD5%)!+$%D?@@EC1$50@952E/FHCA8.16>0=.''(74-&8:9!<:7??GF29',-<2#6@.(*#"BA!G8>49B+C@3!>>
@r7339
TTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTCTGATATNCAAATGAAGCCATAGGCATTTG
+
4*G;!,E%'<8,/7E%=5=*B6G-*".,7:%0B71?*8&;(4.)!*.B@+3-$23CE%!)1'%;78.
@r7340
GGCTGCGCTGATCCCACTTCATTTTCATGTCCGGTCAGCACATTTTCCCG
+
BH!8:%*!#/'8-(-!8!;7H??(@-E58;789$"#9>3(@:2,C39H.,
@r7341
ACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCA
+
-",-3<'6B6<2;90A&5>F147(,35D*$2'=>,E38B;6C?C,F-2=@G.(D5#.'$=B/BD
@r7342
GGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTC
+
;+%69).5E&(<:%*/,HG/7#)<>!A*+#5)0(&.9.HG:.9E#8H:73A00F7;,
@r7343
TCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTG
+
65D:7'1"5$8D)99/"<HE2;!&*@-;;*":A*/84!F9.0,35
@r7344
TATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTANGGAACAACGCATNACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGAGAGCTAACGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATA
+
&6@#&7420C09$.F/0*74D@/.=D=C-5#+':G%90G=41-F9)C+C)5>$-'73/C-*9!C4<#8*8!&$?26%+,+@)5-!F<>9>E6@"64=E3&!6@"#H:(349B>7ED31DC)+/+/368,$8/3A4347E+F4/+B31)&375",2="EBA@H!64834162=F8!&&--9/"
@r7345
ATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTANGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATAT
+
+=(+'509G/B*!H56=7;4/F"!3'"2;B4.3"C"$1HEGE$F%E1;$$B#.>E<B+=,29#CD32H=A'0,)&G,)E!'0D-A&DD21*<#59D=/D-8-,CE>C*H$):+%*()H99<=?=C<7"(0A%=9
@r7346
GCAGATATAACGGGCATCAGTAAAGTCCAGTTCCTGCTGGCGGATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGAGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACAGGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATG
+
<@7E*:H"75DD6,!7#*F:,4G&E*988#;(?*9<(B?961!CD,?;EA<DCC@:?+2>0-0C2G40+#C#3@-H)8*G&4D790>:;A<&F8E)<<%3?)/,!4C*6DGG;2@H2?/B4A48+".1843-<+54>6)&(AE#0"EE5$*?=!<F3#2:1",%GE.99-.C7/%!5=591%29B-9#>>;=-H<?8,D).7.F@A62?+.:$;0D6>*);</+H6!>88%->&#4610#77!&%2,'2GF?9*!6D"C
@r7347
NTNACTNNTATTCATAAATTGATTTAAGGCGACGTGCGTCCNCAAGTNGCTCTTGTGTTAATGGTTTCTTTTTTGTGGTCATACGTTAAATCTATCACCGCAANGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATAT
+
&'$&*%)#%*%*+!*&!(*#$!!)%$&$")(&!#"!!'($((&"((%('*$"+!'#)#*+*'+*((%%$+'+'!*!$+)%&#(%"((%)&"%*'%"")%!*)*##()'(&&&#*)*''''%(#)%&($'#($$"$(#&)("&&++*)&**$**'$)$*)$+*'!'*%+'!(!"$%#'*"("$*#+""'++"%&'+("("&&&(!$'"(#%"'"!&($!)&&#$+$''#+)$##*''"*&###&'$$%$!+#!$*+%")#)'(
@r7348
GCGCATTGGCCCGCATGTTCTGATACAGGNTGGTAACCAGCCAGTAGTGCGCGTTTNATTTCCACGGATAAGACTCCGCATCCGGATA
+
0B9#;F6.B)E5:!9,7B1(2B>.39+;-6$7G0?@/'9</,@>)HC--39>F=%E4$>+4$.D#$F9358G)%8,'0%DB2@+#$,<
@r7349
CAGGAGGCCATTGATGCCGGACTGGNTGATGAACTTGTTAACAGC
+
?8/:(>?B'1)*G!=C:G(/"?(E+B4!?#(4*F.((&D7!"E*A
@r7350
GTNGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTT
+
':C!=;),(8#C00(F=%0%:#9"9"#13&!*,;E:*HCB<$-
@r7351
TTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTCTTAATCACCACCTGGTTATTCTGC
+
&:09>D.FAFA+1#9#8.EA7%.1D"@/#,"/A)C*>9C'5*)H"(6-9#C!F#:AA&$&8(F-1(
@r7352
NATTTTAACCGCTANATGAAGAGCAAGCGNATGGAGCGACAAAATGAATAAA
+
#),!+$)D09778AG7;,G&C99;63H>819"8FA;9'G($G=:-)H%AC.<
@r7353
TTNAATTATTCCCGGACACTCCCGCAGANAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAAT
+
2',DD:F?H),C87%-$E7:/"<<32(-A;5.?;>4%7;;>*@'-(=(919**(C#=*:(99/!C=,-G9
@r7354
ATGAAAATCCCGATGGCGGTGCCGCTGACCACGGCGTTTCAACAAAATATTGAGCGGATACGNCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGNATCAACTGAG
+
!,0G/B/,=6G)32.A&->>9H)16%,0923*?=#(@)-H@=DD#9#B+!F9+7:85*06<*2./,2,$2;=E'@5#B";67E<>F;+C$2!F.!A-#G<(:BG=.,$427C$
@r7355
NTATAGATCATTTTCTTCCTATTGCACATTATCCTGAATTTTCNGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGNAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCCTCCCTATATCGACAAGGACATTTT
+
%+<'<-0A1F?<*3C#:'EF-;0-",BE7#D&B=@HA;+6;1&+CA-=!F*$'2,%-2"/C'<5#AB6->&6:EFD<G,GE50(/":A=9"AC%9<4+(/6!:A,24E3#?.9:58/@%.(*<A#+1FE%E/''H:C>(#E8/E8*<8?!>!+DH<%39&2G)
@r7356
TATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCNGGCCGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAANGTAAGA
+
8$/=;1+*AA&@AD989H?$3G5:8*'9+<,-B'-1A->06DB*%(>."0F?,329)=267,&*G,EA)21!8@8;7=7(!)0E;&,G14)ACB#E<8((*4B?%2<=+$6,*<*461*B$7#/4$,5,=5;D<
@r7357
NTTTAAGTCCNTTTATTAACACGGTGTTATCGTTNTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCT
+
*7H.A"?-=AGGE4@6-5397%E433G+2:'/=(+/$667&%81FFE*G805(19@$$5"63,G&'@&,E@G7(!-$9(A5$+<F56?*;2*6*F6<'7,:HC(9*@.'DB">60(52<D#--/#H.C
@r7358
AAGTAATGCGATGAACTGCGCATCGCNGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCC
+
!F!B"9!7/#2="5%<7@>=0A9G*<+/6$;;AGE@4:(H@G8:/24$E1;1!6.@;G$<0"")*(!>C*9($)3A)C)&DDF+6C60@D5?$18F0,34:3;/7<,@)8$@H)"FE
@r7359
GCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAA
+
?5;"'4*?*3=")?H*-+(7,F)/!@7/B8A#F/;-F)=-8'""<HE:C,=8+5E9ED(,5G821=++*:9H%F#:85:,0"G8!%="/0B-@:(./:7:=<(#1,869F;4H3$$'F
@r7360
NCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTT
+
!A"-#,!@3G0+B::61/356A:/=>4#1288-GE=$079.-(-FC.8HEF<??7H:5E@(@.+=,(D@2"BC":$'?D-F?36
@r7361
NGAGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCG
+
#'#+)*"!(#%'$'#*%#!')$%%(&'!(*!'*$#&+&)(++"#*)*#*(")"#*'
@r7362
GAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTAT
+
2=)21+AH!F>00.61'=*#EDB<5(G-C.4/1,5GBA':8H!$"@A&$22!7=!G>,-,
@r7363
GCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGCTGGAC
+
5)73,0)1%='-@2%&,#E2A"+&C.D@'?.=@G-/1<)::,:
@r7364
GAAAGCGTCCTTAACACCTCATTACTTAGAGNGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCAC
+
HA?/.=7!A9)@'A:<*=/50,C984/0D6(8'(C3.?'(-9'69%.!0#241$"!'?80)$)C2A"B(/!;;"3C606+.'+!F2:B!@3";6910>&=+)"-6
@r7365
TAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTT
+
C2FC-7(E@*%%!A3+,4)266!#+$<@80++202:FF'6;"A<=AH!6E'7A:'.EE+@A55A>GCD:DE;$2EB=%6;*?G$(#=;E2=H:!$AHH!%B0=;1!E2%-4+F&0H
@r7366
AGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGAAGCATCCG
+
<'!HE9#!//#",<4/D*;>;&43'#)EGDGA%?<?;BH.()&'9!<+$C#)E<$.32%$2DH
@r7367
NCCTGCTGGTAATCAGCCGTAGCAGGGCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTCAGGAACGCGACCGCAGCTTAGACCAAAACAGGAAGCT
+
#*<?**H<"2'*5=3D+(-B,@%&)%1:58$%,00EF!';98;E"A(*";H=B%88!'".!%&7F!F+F:@;77H17"0DH&7+!2F@BG8;,;H81H5CD-)474-/;/:(-F+%G!,&FH"B2HB:D/<!,=%8&<+4#;=89+HDB;&B".+0/&6.5E?/%1-1-2=&01=G"'H)*-%8@+*B<#D31F1F?
@r7368
AGGAATGTTTTCACTNAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTNCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTTAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCG
+
+'*&+!!()+#'!'%!*%(#(&"%)$$+(%''*"#)%***'$++*+#+)+*'&!&+)#""$"%+&'*"!%(&++!$!(#(+#+(+'+"(*')!$'"#$&"+%$%*'#"+*!&##)%*"&%!%!$+(*&$&+&(#&)!&#'"""!
@r7369
TGGCCTGCNAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTC
+
-2(/>4@G+.@2E$G79/"-2<3%)B>HB49G3?@;2GD;$.$5?#+2"%)<).3;-#-
@r7370
NCGCCTCATTCATNCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCCAC
+
"'+"&*'*('+$"$!&)%+!%"!)"*((+"&*$!!&$(!!+))"%(""&%"(+((!!**$)+%*)(*+)#"($"!())*#(++''#()&)$&#"'&%'
@r7371
GAATGCCCGGCCAAACTGGAGGCAGGAAGCCAAACNCAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCANCGTTTCAGCNGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGNTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATAT
+
,&;4#;*7GHG;!$;)&$6"E<G#C9BAC0/!A>#E%/<:43-&/(5H.9!.08+.+837)$;C>%;>>2A:8'H'G9@#%>1!,7&&=!04@F6G><C3C6B49;%;">*B20&$(-7+3),6@B'C-E#.,"93&3&2!,6=%C6A9"0)?9G"=7:=C%=+1+&A*<%;&763"(03<:7#-6F#.GG*"-2<G1%/;F'*)C:@)B)10(*4D-F'!C78HB/HC"1A8G-$&H!EC..,362!??+*&%E!G(6*3@0'+D6<CF,#!-$("14-'H,BH+<.5521*E*""CE%F:A*-83D94#@
@r7372
NTATGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTANTAGCACCATTTCTATG
+
#5><?"+855#A0G?/*7DD=6#%"><%$B=*E@%=C*663&;7*!#8C/><;;*4A,2>6AA?H5>
@r7373
CCATTCATGCAGGCCGAANGATNTTTACAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCNTCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACNAAATCGCAAT
+
F;$#*0/"??</6=/)EH:E4(#$AD#8"*GE8"3</F8'GA42#3</F8+"">+E6@??7)C/=$:-F.AE*>20B#.-%"5,$6/*HC8!%=/=F9DA,=76)#:@36<DG@,&;!H)37?<AH&/@7BG294"F1-.5=*>2D:*8H%*)DH,:FGEH@**89G?/!B64$><*.DE!@E1)53@?/!-9G&$-""#+G>.B;-5&A&D=-0<AHFA'31&/..%A8-<$#55G'#('4;;CA+-4<0'2"5"A=*D6)+D*03"/+<,2-4"5:(B'?3(BE8,D*G./#/
@r7374
ATCTTTATTTAACTCCATATACCGCCAATACACGTTTCNTCGCGGCACTCTGGCGACACTCCTT
+
%B!C"+@4;7GB19910E.A6DA'F"=B"!D#3C2+G'.65"+9-4@'8;G/H06<&-)#+-11
@r7375
CCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTCAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAAGCTGCAGGATGACACTGTACTGACCGTACTCCACATCCA
+
)F;'0@';!$AA2#*%C25"7C@H"B%.+4*H:$!)7G;;CA-3,&DB6=0C75(#<5#;+&*/$@C%A:(?/0)3A#?/'3AFHEEB.+BH$G;9EGC>AF,+B/7%"3E,AG(#?:2E>B-H3D7<+-AA
@r7376
AACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGNTGGAAGTGTGTGTTTACCG
+
EG#1+B,2>"45:"<7496H-CF(21C@",*4)B46*-?1&)F==7()H!.*:C!1E5F,1><G*CDF@+>91$@BD;:(<-EHF5-2-AF;+:?-8(?D'%0-)H/2#6(@E(>3
@r7377
GTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGG
+
3?$=A!*AA+#71D0*()#=@;=-,>*/.AG+;-%-H2-5G*?%-:<"=6BB0C?H12$#D::;1-C%D0
@r7378
TCAGGACGACCAATATCCAGCANCGCATCCCACATGGATTTGAATGCCCGCGCA
+
HEAB8681E'+@<E%'+G7$);2=*!5;GG@7?$F2"9;+23;B/?G:E:#D3A
@r7379
GGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTA
+
&5C>.FC#B83/'/=*0#*"B'CE9BH'=*B1)+GE/C#><;2#"$<!3&@.->@?38%2/3G>4H
@r7380
CGGANGCACCACTATCTGGCCATCAAAAGGATGGTCATCGCTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTT
+
16G?"#%2E,$:#F1+8D+-@7?H5>H25(B;C4&..:H07HD2405;:8!:8%@8<4+6*(B@;'#G4C""$$G-):"/.526H
@r7381
TTTNNANAGCATGNGCNNAGCANTACNCTTATCTGGTTGCCGACGGATGGTGATGCCGAGNACTTTATGANAACCCACGTTGAGGCGACTATCCGTGATATTCCGTCGCTG
+
&%)&$'!(&(')"!'#"$"$&)"!%)!+!)*"$&+)""*!")"')"$#"#"&(*'(("'#(%'"%!"%'"'%"#%"$$$$()#)"(&+**"""#'$)*'"+*&"*)&"'%%
@r7382
AGCGTGTNTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACG
+
6;=1'<<726-D88>3>12(@(/3;1*!@'H1B!<@18,F.B6!1
@r7383
TGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGNAAGTTGTCATCTCTGGCTTGGACGGGGCGTNCCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCT
+
4H,+4(1$8-/-B/!*);G"+F38>96C'*+34F5(3.;$??H)1;H4/6:'!F-7G7D,2@A-4=(C7'FC16):&<*;3#9E*77.H)H?#;$'$E#5"G9<5,&-,=;2-/(446.6'>H=4<3/?B96%##&)=D/57D08C=C0:>06%%:53>#3;.G628*1G3#(%'$*2,'18A?>;D7(3*&A-GC@'<H<1.733C?9H4'8</B-C45!6DC1DHC)!0F6:CC/:*2E/HE/"B*@%";.<3%5&)5DE$2%C29=C3!+;"@3>(E/3%6@.E+<$8728
@r7384
CTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCA
+
:E8.>5H*GH<%E$$#7H'3B=11!BHE.*4?@-113DH2
@r7385
TCCCATGTCGGCAAGCATAAGCACACAGAATATGAGGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCT
+
.&.38H/;==7)#'5)"A&%?9B0#6C9$7GB,";AHC-G)8G3!..@/:(>5++&66;131C1+<$5%G).$"'8EG(6&?8?G6B%4E6C.
@r7386
CGAGGGCGCGTAGTTTGCANTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGNTGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGA
+
*%!'++%+!)('(#)$!+*)+"(+"+&&($"(#)("))(#+!$'%!'&'($$"""($*!*%)++('($('(!+(&&*"%$"'%'"#("'!'"%($#!%%&+*!+(!*&&$$(%&'&*(#&*%&&"$$+%+)'##+)($##)*&'#)*&*"
@r7387
NNNCNCCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTC
+
#!$%"$++*%#)($**##*)*!%%*'&*&)##*!))&$#*!$$$(#"#+%!"("")(#)+(%+%+#+
@r7388
CCCCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGG
+
2$HD14.B><(-?F8%;?86+;','(7=/"8%46H+C?17CE(/$0D4)"(C,+!,
@r7389
ATTTTTGTCCTGTTGAGTCTGCTGCTCANCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGC
+
H=D*"4A!2-'3$78335@3-&3,-&.$=0@.&7&3B&(*@+G&%$G":;=1?>60%@>C-?9,23C5D:A6(F#;-"!/3(=+#C0#07
@r7390
CCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAANCAGGCTGAGCACNGTGTACGTCAGCCCGGAAAAGTGCATATCCAG
+
5%8&#EA/1/'#6H+CC,7!9("*!#21F(<##4:79:8E$3AG-=H=(@64<:7/7F)A;;+/6A,?C"/$)7G<..#*3-EF?,*$++D(3;HD4)AC*4'4AH7-21F?7"+@3A,6.=5#81(HD51,E*;.D%3!3E%6>
@r7391
GCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAAT
+
H-+?G>!$G*8@3:/"A1/.8>)A?@C6+,"E0.!&%=/<&@,/5@47.(*4(:!F0G5A-A$4G'</:'@B:$B!%2>9B60#%F=0;#@8,!
@r7392
ACTAATAAGCCNATAGATANCCACGGACTTCGTAGCCANTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGG
+
@0)@@),C<H%GC!(.-);=D@H?E%<@94#.&6GE20',"FH551BD*"->B185/'./E=,=+>#-8.8?73*9),2B#@4<64?,&F9C>>@1(
@r7393
NGGGGANTATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGC
+
$.'(,C4*%>1.66:<B,&"1++5!2:A7<(6(2G#;)87$6/-*647-9B#)-C#!&$%5,/11
@r7394
TCCGAGNTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATATTAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAA
+
+9$3<-!;:5/A,D,*9*.$E,-5);!1,/H-*2-&)4-!B)@?/=4C7:*./C7:*8!3;<=/>9&#=@?G3#GG*C':"4(:(:A'$H1&"*"%)B0<@,B?A8FC&@/:E
@r7395
TGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCT
+
/&<+8DF10@#=1&8?5*+$).?"4,%3#E03?>D#6*?G(#2>%<,,'.4/*)&>5(;=B/?/HB9(@@+=<E:CC413940:5+B/$.&61>G2</*"6+G>1&@CAE,0B=-142@#31,>F:$&0')%-/1E'7=0,+*+3$(D7&7('2"6".(,,1H;C;#&H<8D%C;(GA!(
@r7396
TATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTNTGAGT
+
31+D,!)/$C"1EE0/)8-+C8D'"86-5A)+#<263(5C0B89:/=H9D-AC>,+#/''+%7&F09+'C'.&8EC=7
@r7397
AGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATNTTCATGTCCGGTCAGCA
+
E0=?,=9+$A94@'+@'("%&#2F7!"+92#'C>-!C;-)6B<>+?)<4-E<19)
@r7398
NATCCGCCTGCAGGATTTTCCCGTCTTTCAGTCCCTTGTTCAGCTCTTCCTGAC
+
"=>%!5(!0098.0"=;9?30<0:1*89$;/'$&A-.2H4*)1&@<;++(!(#-
@r7399
ANGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGT
+
''5209<&H17H/D0E.+-//BAB'G06BD3,:6.*?*?D;CG1
@r7400
CGCCAATCGAGCCATGTCGTCGTCAACTACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAANTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAG
+
84D322<(,6+6:)9GB>%C**HF1D9>C!5(AB5=A:A=+*5,B).8EF$C+$F@)<H&$*8"'"6C);;<*>/)F%#!.&C;/<-!39A<5+;,994$CC5,-"+3A0A(042H=>76=(8&E@'B;-&6(4+<0+1E"HD=D/920"?3F2-#<'+61#,165:@B64"B@!.B=D<+*GD&
@r7401
GGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACG
+
2HD073*9,G0H#3)?:>D*<42;>HA7:3;;%>!(46:-6':7H'++@./#-!:8:H93;#H.;($%6&(<0EBD5="2G$"8"(:''AE!@F<A!/D+H>::54<5+=;B=D@9*;7-!)!=E)-%'65524"BF->.E8A&
@r7402
GTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGG
+
F7.06D'E/(<-6B3E2H#1"5G%.2&(*"%,+;>E=C-F!-7/-)A3-4,1;,7&FG9%#>30%7@8G5!55G51
@r7403
TNCANCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCTGAA
+
'"%#+)%"")$+(+!&(#*"*$'%&(%"$!+'$&+!(!)*(($!$$*+#)*&%%(&(&!
@r7404
CCNTCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAG
+
46:3*;D%H!G?6+<F.(A"(7(*C>!55&469+-?3@55=#.449%,H81-D5G,>04E9.48+9&D1!&/
@r7405
GTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGT
+
H@8)E;/&0'&F3+#2#B=*;&4(@26#'<H;%C)/>1..H
@r7406
TTTNCAGGNATTCGTCAGCCGTAAGTCNTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGNTGATCTGATTNACTTGGCTGAC
+
(*($+"%#!!$##*'&()*)#$&&$*"$+'&)$$%)&(()(!)$("$$(%%(!$*#!$(!!**!!*%($)$$"%+)+'%$))%!!%)*(*"&'$$#+*#)+")%!)"()#&!&+)+$$'*&&)%($'%''$%'($+))$%'&&(+#)#&
@r7407
ACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGNCATCGTTCGCCGCGTGGTGAC
+
G.6:=GC!/9E";@('<G%7FDH.1+*8;+!.15CB*7"5AG%B?,&.?A''F,G01,>!4"(>:$&5,=E;E:H)D)@;()H*&<?$<<(0=4
@r7408
NGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCGACATAAAAAAANCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGT
+
!D650G55:2:,'=18<!&3<C$!C1)5$(=5-3B41+;A-EE<B,+08!!1)G0":"98.G*9?ADE9B4%=4:H&"=#BDH/@!:!5H1G49)1:4#%C!$BD12A''@C$<?43F
@r7409
GGAGAACATCATCGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGC
+
$=18,(5!'28'4/,'?$)F'>#4(F;;C#/.@<+B,%!(-4H/+=3<C2:*E8':E
@r7410
GGTGGGGTCAATCCCGCCAGTATCCCAGCAGANACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCANCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAGTCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGGCGANACCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGA
+
'*'$+&#!#%&#$%*"$%*&"$'(+"+*&'+)''#('(+%*+%#+"!)!"'&$''*&#%'+'#("&&%(+'"((%*'$!'#'+##&%#+(&*+$*%%%*#&#*"!!"$+&(*"&'(&(%"+(*'+#'+'*#!'!"&)!%&'#*)*%*)$++&!#*+*%""&%'!$*)!')'$("#%'$&!#'%)!(&!#$'(!+$*)%$)%+*%$%($+*(&'"'+'&!!)%#))("')$&*!*+**%(''*%("+"+*""#&((&+*)*$"($%)
@r7411
TTCCTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGC
+
:H:1;/)?/(/>8#/E17-2$G@")'<64(H?)3*,-E8#0+;2B5;.',1<H<F#".@)6!6
@r7412
CNGNNNNGTNCNTGCNNGTTATCTGCATCATCGTCTGCCTGTCAT
+
'(#%!!))(!%!"#*"!$++')+)!&#)&%#"(!#"'+'"#+)!"
@r7413
NGCCGGCTGATTTCTTCGCGTCTGCCGTACTNTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACG
+
"CD&6:=E=AD;3##@!4=/,CE1,?H904!0EG)&2@C>+E5+C<%B<;&:#H-)1&",>!'0H!$D>BGC8-*&+7!G!33D)
@r7414
GCGACAGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAANCGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTNTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGNTTGCCGGGCGGGACNTCAGCACGTCCGGGTTAANGGCGCAGTTACATGAGANTCTGCCTGATGGCGCTGTAATGCATATTGTTCCCAGAGTCGCCGGGGCCA
+
A,<./+<D'!D1=F>"6B7(D%?=,1$G>E*H=5,,+C#0@A$12G,B&::5342/;1E!7,<&,=&$6%G1<!(!=;#<?#-C(!,()%?!.CF66<G.5@A6*A=#!+79/:'3'2EH>'C7A+74G@@G=9G-A7",>,C+&7F"4;.7!;$*F:2G=%?H'H845018B0BCF+%*0=-1:)G2.#<,G9.8<$3*3)6"/:63'."><D";8G?09:3ECG?1-4D&046?98D;,4<<6!)#)!<5;=F/+8A+F"?&9"4AF7;A9<;E>&3&&$.9!6G=+*@"?0C&7E!#0G8?G,(5D#',:0/6"!'F5;GE%@F96*?9H:?H27,G316)=D(>)'4:&$)>
@r7415
TGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCNTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGTTTACCAGTATGGTGGCCA
+
E257'468F;7!(@3?18-4:%B&1CB>E(),=((E7#,FBH&-*#"12G(9?-1:%*$D<3C84"AB8"@-C<*54@0F>5H=A&0D'/A*3+$,C<8$&8!!6.603@-
@r7416
CGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCNTATTACCACAAAGCCANTCCCGGCAAGGTTAGGAACAACATCCTGCTNCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAG
+
;;$B24&F&9D&)1:6:(58;)2E41&4>D)"F#F:8,>:%;F")(&A<&>3&40$E4G,9!AEF',H9&B>=7D$77("46#6,=#)ACD5&!!"?@*+EE=BHA7A&9(83HE:>7-=?>C2+F>,055D$5&',G)8@!:1G;0"H+C0%:C($6<3,#A/)7:%9&B?8)0E5%3/<>1/3,-=1.!%$92,78C?8A'/522!+/.%;$C<?(G+$;$)5=8/>
@r7417
TCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTCGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCA
+
>95!E',1-=85%DF#2$.6#H$+(;0F,7:2%G4F;<"170G#6H67G=F=2B=8*%>$*B&6C%?A.*!/&7F)..&6$5<4@"(!(H+(>+*3./AC#2
@r7418
CCAGATGTTTTCGCAGGAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCNAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGG
+
G3':C$(@.&9$5E8A:2;D!5*.9&F03&.H&2+<H"1;>+83"FG''35B?3@,'28@>#):6B5E7<A8;6/1=&65=AA>HDB0%"G-:?"?:2#CA.G7,GG&HE
@r7419
AATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGAATA
+
:,C0#.66);0&&)?ED%2FC)D8>'2:4CB<")$75D3G-%*!%F-7%"/!;F<D2)
@r7420
NNAGGCGNNNGGGGCATTTGACTGCGCTGACATCATCGCCNGTGTGCGTGACAT
+
!&&*&$("!+%+(#"($)&!(+""'+#'*$$"!%+)*'%!&$$%)$((*!$$$$
@r7421
AAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCT
+
8&HBH97B=:$><(#-H0!=@>,#H7HG7',F5A)%-,E1-E+F838$)&#.(0;8%B6E)1'D"&+,"F5-.E"?1D<0)13$A87*/@CE)27D>:%CEAFC#A;95(C38+<%*G#+C'*"3$1'$7D7.+E>5)%F/#7337,EE@/)--D%#=HD.8H+3%#8*E/7#?E@""8/#
@r7422
CNCGNGCCCGTTACGGGGNTTATCNTGAAAAGTCCCNTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGTGCAGCAGACTCAACAGGACAAAAATGCGCANCAGCAGAGCGATACCGAAGCGTCACAGCTNAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCATACGCCGCTGGAGAA
+
'(*)&)'$%('&'('('(#")$(+!#!('*%'('&"$#%"&!")("%"$)"$#%!+*'&$*!!'('('%!'(#(')(!+&((+!+"#'(''%!$"*!&+!$%%"*'++&(++!*(+#'"#+*"*'+)"&+#"'%%#**%%#*%$)(##"*#&++"!')%$$(("+&&'%)%(+$")%*!'"++%%"*
@r7423
AGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTTCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGC
+
HB4$:3D.!,B.00;646%,C99*).E81C%-:>&"?%4%CB%(<).0,5*C$40A:$#$/1B@&G;+1>5'H#618$%3A?'A-G;78G8<GA!0G.(-"-83C:@E:!-7/'<#%EEG<%;@3.
@r7424
CGTGCCTTATCCGGAGAGGATGAATGNCGCNACAGGAAGAACTTGCCGCTGCCCGN
+
A58**:<<:FDE&19@++?/48#1:9;%???&9&HG0<:9E?3;B83<=+H-<E;%
@r7425
ATTTNCTNTCNNTCTTCANATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTGGGCACTGATACNTAACTCTTTTCCAATAATTTGGGAAGTCA
+
(*))!*"$$(""(&(+")+'"%%$%%%**+&!!&#%$!&('&*&%()()#'%'#%*&#%!$'&#%"++*"*("!&!#%&$!#)&#"!#"(*'$+"(&&
@r7426
AACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAAGACTTTCTCCGTGGTGAAGGGATAGCTCTACACGG
+
<;=#."G586E&9H0G=/=>?5.E>;>%HE05A%8*28))!0&&?$5)A=,3,/*?H=$9"5GC(-@@F/E4H4'!/>9@#77H7DE>>3&DC
@r7427
GCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGA
+
#$+*()%(&$$#$+)"($"%%*!%+%$!!#'#%("'##+#!&*"#)&!)&$")%'*#")+%(*&)"*$'&+'"#**&)$#%$
@r7428
GCGCCGGTTCAGCAGNCTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATA
+
#E6*C0(F<A71D$.H?H!/'5,7+/G@#?/G$1#2#+3@:!"#,4D."2;C2@@ED&9;@0!#%D4D6FA+/?.+7.F36;"-7E=&3&6(*+
@r7429
TCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCT
+
!?&*58?C:!)89+>6B1!$-&@E3&('A4(<<9'<.0(;A-B#6,9H4="#0BC<6);1%'0<4A41&H76>@
@r7430
ATCTACCAGTTTTAGANGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAAT
+
C<'/3B$E0=+BA4%G:9-/&"D?0%>%0<96B00C0";#%'-C&'3G=67>&A,11#:.D06(;7)+"H#<,CA?
@r7431
ACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACACTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTA
+
C:>'42A:->5E,$C#B33*</EG$31(5DD:(G=;,"0>G$.,G)G0==*F;1B-A0?.D<$'.6&2*76#(.<C:1:8>#22A%24'A'CD5%.AE58-"957/#AF%!98H.!1
@r7432
CGGTTTCACAACAGANAGGTCGTTTTCTGGCTGGTNAGAGGATTCGCCTAGAGAATTCTCTGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGA
+
&2<=3H9=CC*?:;4(/7G65&83<!G3:==D7H:;/'*593F@?)C'883:E=5.+-E'!0!11/F%>@E(%$"7CD%**B8+HFC0HH9G$(?(73;9:,05@)19=;4ED$*C7CB'?D+"1G%B1@?=,1A$%=5>=B--@E.
@r7433
CTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTACACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATG
+
%B;$+-"+<6H(?A=BH(D<6:7:%+&'E/B.>A!,98E'>1<74AG5H30$6261*7;3G4A'7&!3D7':.%5'HGC44.=*'G,6A'07(0,?1>8;",E6!4D5&)B&F?59?-9GBHF"?&<A:0DB+0!+$*E%&6FF=G?;8>C<#'8D!8$C:F?B%D>B"/;=FG
@r7434
AATCGTTGTAAANCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACG
+
49D(D>#*&9@HBB-F774/6'/5C*%'&(=>67,;>>1C&+0!C69."
@r7435
ANATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTNGGCATAAATAACAGAATAAACACTGNACTGTGTATT
+
-$53.$!#A:45#9H8)4#("93#<!+E(3->0%3CF#9>!&D#6!2-#F5-DD"38&:A0==*''-/4.DC"!G3<1B--7G$'&&.FD>*=+5G3+/6@?*7!8>@!%C/F$G3)71C,.*>4F<F,F9-5<
@r7436
NTAACGCCATTACCTACAAANCCCAGCGCGACNAAAATGCCAGA
+
)*%$!)))*+#%(!(**%##)&'+"#)%)#!'&&'"#(!)+"#*
@r7437
CGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGG
+
.%==+(5@<$"H4>#4@<46).C@:8C6,=>53FB;E=:78-;6'8E*;83
@r7438
GGCGTACCTTCGCGGCAGATATAATGTCGGTGCGTTTACAAAAACAGTAATCGACGCA
+
'&(+))!"#)+)##(!#$%$+#$!'**)'(%*#!')++)*+((!%"")(#&'+(+)!+
@r7439
ANGCTGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTT
+
$&#&"*+**)%+)*(#&)!*##*$$$%++%($'&*#$$''()$+*$&'+$))!)+$$&$$))&+)("(!#"&+"'!('"%#!$)#'%*#*'#(!(+&'!)"'"'%*#**"+&'(")+!"
@r7440
GCAGAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTT
+
B!8CH?'51!1#5<743(A=*?0;#!B*37H8>@3;'D3"0(<+"*@9=B#H9@;*EE:!EDA%%
@r7441
TTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAA
+
26"5!'+22>@3#&0D!.#16CB5%;5653(#.+:?94='2A2,2G*-B7$C1*;4=0;8-8.H(&C8F,6=(#7#//<B"0):/1)322
@r7442
ATGTAGCCGATNAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGANGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGT
+
@@FA??@625H0>8D@&333F$3>(0>=#>&H%(E'F5BG2+866D&'C##2"F*%C!E<CE05"0*>6@)"**7F;)6+&A0*D"G,4E&9&8;-8@8GB+=,0-!&(/@3FF-D
@r7443
ACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTG
+
+)%&+++#%(''"!!%*)*+*&*+&#(%&&(&)'"&%$"!+*(#$#&+"$$*)(
@r7444
CCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAG
+
H!"<5!9+.<B%=$-H<G>/=:58/#4F7+@95C@9$"4.H=B5$'0%.1"71.+?1H73#?#7&'25E7;$G
@r7445
TGTCATGCCGTCCGGCCCCAAAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCA
+
;2G'+4+-HA#0+9>+F0%8&-@;@A&7:C!/9439D.(7'3+-6(70G'1"B,2$4?),2!8/97$$894*3%$C$H="9G8+$
@r7446
GACCCGACTGGCGTGCCATGCTTGCCGGGATGTCTTCCACGGAGTATGCCGACTGGCTCCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGNTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGNTGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCCTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACNTGACGGAGGATGACGTAATGCTGNTGACAGTATCAGAAGGGANCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCACATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGANGCCTGCACAGTTCNCCGACGTG
+
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
@r7447
TGTCGGTTTTNCAGTTCCGGAAAACGCCGCTGCACCNACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACC
+
F(-<2='C/G%24?6-B<,5(!AD:(@>7815<B*##E":D")-$,B&&,B'5#%G8.%A>%.5+0-2B87*9+
@r7448
AGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGC
+
2"8F,/6:="0EGC7>G/(7HHA")-$0D?1'++%?<A=-C+#!'
@r7449
GCTAATAACAGGCCTGCTGGTAATCAGCCGTAGCAGGCCTTTTTAGGGAGAGTGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAANNCCTTCCAGACCCAACCAANCATGCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGNTTGAATGGCATGGTCGCTGGCTGGANGCAGAAAGCTGGAAGTGTGTGTTTACCNCA
+
7G&&4<"1"H,')*E/.=+6.!,B-.%67/"AA*<8H71'C;#6"H)3G"18B;8;6)9A38-"#>/=H>0:"(6**6;1#5?".@',6%)G$.#&7>,F4*>!>=$#F80:1#=EF%#;7:CF@D%G?-385H/52628H7;9-D23;8(2.69:6DGG$8>;%DH?00=E(FG71H9#3F>+;AG3=*F'?:&#G%E-('19/,;>,+F'%!DE62(<0,$F5!E)E9.#9?F%0.BAGB2>+.4*0+3>8?;A4<H<1CG,20E@06H0??8C1+!GGB%5G/;*F$&<
@r7450
NNGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAAC
+
$*$+$$$&"%**)+*)'+#'*)$'&''$!#(++%+*!#&&$(&)&)!(&(*&#)%!))(&!+"&$&+($!&
@r7451
GGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTGA
+
/*4H%-+&;F/;)/00*8;>=7@A,/+4=F5G8@-/=)?*4B+/3D.-#70?EC940501F=-4*-+C1&G?(!22/*1-'9(C)=7;=;B=?B9(,+/>3-6;336#/>9'9"1F::/<%3@E#6*2BF4+":0-3/(5#5DC%"0358
@r7452
NCNCAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAA
+
"''$**+"#*$!#''$($)#%$+!)(*(&'$$%'%$#%(##%')$$!(#!)$&'&&)%#$)*!%+'%#'+"')$$$'"')"%(*+#!((#$+$'
@r7453
TCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTCA
+
-CE@0+!<1H"G&CG=A:5*A6,C1,G!,.!!=,2=><,8<4#7!9&+,B72*00A@)A=A"#8>EA1=<H9B?!?5=BG2?58*GD!>.H$,;6(,2:8*0;GB#<=(,A+.6
@r7454
CAACCAGCACAAAAGCGGAAATCTCGTTCCGTATNGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTG
+
1%17@7D:$*-3-,#7%78F3+!(=#6*D<$&4@,.*=1?F5B&D;62!36%6@C6+DCBA1<-<3B"2.1,7
@r7455
TGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCNTAATTGCATCTNCTCGTC
+
?F2C3-.39>*)"1B);H+%/HD/>F2'"?644@>AG..81@9#CA8B7@!"A#2*7'"#.F73):->1:#1(5F:#6!H<%@#/+
@r7456
TAAATGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGCTATCGATACATCAGGAATATTTGATTCAGATGA
+
B!<A7<4%5&2!AF?-0!0'/=@AHC.8"<5;F27*)6*)>G"7?3(#3E9"<$@D+2)+5%:2/+9?B>$<0B%H"!)DD60(H'D(6.=0F9%;A5>1)1'B8$2)BD$46%%0<9((1C2(<#*,F/C>,
@r7457
GATTGGTGCAATCATCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGNGTCNAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCC
+
++"*+"&%(('**%)"(%$*+**!'+&#)$%(&*"+"(+"'$'*!&'#)&("%(*)("*!%#*$#)+!%+%'$$*%%+'+!*+'%&''"*)(&+#+#!$(+*$*(#)+%$+!#++&*%)!#$$+#%"%***$(%)!'$
@r7458
TNCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTT
+
)$%+()))&(**+*!&&!))$!%!(%"#&"*!###"'$%'*(&#)+(#*
@r7459
CNTTNATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTNTCNTTTTTGTGCTCATACGTTAAATCTATCACCGCAAG
+
'%*%%%+'!"&+&)!"+#$$!*+&$)!$+(#*)!*%)(%$%+"'%%")(&")""(&$)&"$+"*""%%))(!+!)*')$!&"**$!"&)$"#+*)"
@r7460
TTACTACCTGCGAACTGTTTCGGGATTGCATTCTGCAGTCCTCTCTGCCTGCGATGGTTGGA
+
$.7?(B$@$0CB#=;@/!F4+$G=BF>!$@'@@%0?7D%E9AEE?1??%(2,?2H*"%H$>$
@r7461
GCGACCAGTCAGTGCCNGACGGCTTTGGCGGCACGGAGCC
+
EF6!7*3"1=0A?F=!9%'+A'0CE!"@1HD%'$1DE=#?
@r7462
TNGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATG
+
")4.8BC:72!<HB>1HF37+39$,#F->.8D<G;A&>+<.*==!6'(+B,B
@r7463
TGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCNTCCTCGGCAAACTCTTCCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGG
+
':&GF+)G,6*</:,.;E.!AEG8G(/EG512/(6)$D55;*E?,+?()B01$="+.7"<'E/+A%7:B4!G>>A!96B=#5$?:7*H2.@$-+%4E$:0%G18F;"ED2EG0=2=?)#%
@r7464
GGCANAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGNGCGGCTGAAGACCAGCTTCGCGGGAACTGGANGNCAGGCCTGAAGT
+
&$")&+!)"&"*++%(+%#$#&!(&%&*+)*(*#+((+(&#%)")#)'"$((*+%))$''%*')'##&"+$(&'""'(*"((+&#'&)'(!')*(('#'"()+!#&"$((+)))*+("!"('$+&
@r7465
CTCGAAAGCGTAGCTAAATTTCATTCGCCAANAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTGGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTNTCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGC
+
?5'B,FF(G7>'&76-HF:D4E*B.<%<:'6?5B=>44BEA?!.9A8*-@8(2=+:,%A7/%>!:=<1C1+#.;:)F.?">;23F<4DC!%-8?&9&.7>D"$=E0'&-,>EG4566,'67::3#@!;8=682;88@F1&29@!)%5C4;FD7?%5F7#*7!7.=(C(H3E2&::F96',)-8-&1=::E&AAB%:+,=;/3C>)HD(=-?!6)96!9(1>';D8D)B83;#42C)BH>$470:.42#?(C-,
@r7466
TTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTG
+
$-DC#8#)1=G<7H7G*'E,&8@!=6+66*$%+="5#&A(G"7?1*<1)17*?0;#6)H#0
@r7467
CGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAGCCACGTCATAGACGGTTTTNCCC
+
;6GC"#>>/:<+(4E@?@<"(/4B@)'4F&.#CFF!#';;(B/>31G#E9@!/;BE*;/0!>*FB*75/".>C'95#/7*G?1(@4:E%#'
@r7468
ANTTTCCCAGTAAATCNCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGAAAGCACGCCGGAGGGGGA
+
;-F*DE5$=1)3.?!D=E$B&916%+C1#*2"G@)&3>))%):5G1/<D<>D+DG?%<4;")?/AC"?4#B1-<1##?F//6+BBH4(A887D8?6G:#!@B6AC?"&-(
@r7469
GCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTAT
+
C8A1A0!A*#.B%/'#4*@9<B("D9!9A/%D:6,(0=G>.:;;'
@r7470
TGTTTATACCAACGATATAGTCTATTAATGCTTATATAGTANCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGC
+
0-C;+'-2"D7D;CB!=2<;2419&"2'DGC@A8)3?5D2/)$A-5=1E=$,21.F;A/H9?$03>%E'7-@%'A6>!?'!9/0A)H2=3BG1/#?4
@r7471
TCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCT
+
'B>-!1'F92*8H!%7B<-F-,)D620&;"@/-$0++C8=D2D7G
@r7472
GTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCNTGGTGT
+
'/%#B&3*9!B7A>+!C.A16>3&C@;!%@(0#+,$&)-95$+@;-8<'@3@H3"48'+.699E+?@6D?5-.A,"9B!.:0.1>*1,)C:?(>6#DE%+A28$B9,HF
@r7473
NGTTCCGTGTAGAGCTATCCCTTCACCACGGAGAAAGGCTTATCTCTCACAAATTCCGGN
+
&#E)387B.H'$0-E=&AB-18:>)%B;/>+?"=.B=;?4702%@E"79:H<6379B"+-
@r7474
GACCGCAGCCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGAC
+
(<A$00).D$;?*%0:/EE:*C5*?:'5+*<A,-7%12H43%H@,1=5E(G9%BG%4?;CD(=/
@r7475
TCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAANAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGN
+
.7,2G8E9(291=D<DF2A0,.:9+<?9?F:9#8=8-&C(.!4A.A&D#(##"*(7/,%@F*#H(0;A%0&@56AG38@70HG#1!+G-&0!89>#5#<"==<456?/
@r7476
NAGNGNGGNNTTCATTATTTCAAGCTATTAAATATTNCTAACAGGTATC
+
$)"&'"%!'!+%"%'$&')*#$(''$(()&(+(%)+#)+)#()%))'*"
@r7477
NTATGGTGCTCGNTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTNTACAGACAACGGATAACGGTAAGCAGAACANCTANTTCTCCNCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGNCTGTTCTGTACGGGGAAATGCGCGGGGGGTCACGCGTGGTTTCTCAGGAGATCAGCNCNGCNGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTT
+
!,G+8DF92-8A"-G3<@C8!5A3E*(6:E$1>)-G0*'8%9A8.@B(>;)!&F0'@=A!)=58$H?!H.B<-&!/?#B@<$46$B*,+<()/)5=0/FG>>#7.029BGH$??"@>#6D,,>&)/=>-0#82-6/;@8/05;4.-"2-50!>>&;BE'=D"/A84;*-6D=*E*2=$/=-0#!1ABBC*7,B+2AC;03/?C@5H0G78F"6!G<7C25:<@"<7E4&.#8=;,--6@%101>20'CA!+
@r7478
TTNGTNTNNCTCATCTACTGCGAAAACTTGACCTNTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCT
+
%)&(**%)(+$)#$+(#!*("%"$+&'*"#)%+&"(#+'()($)+%%$'**'"(**%!(!)%&)"&$!!")+%%+*!)##+)++&'"&&+#*#'"&+*)&)!*++"%#+$'!#+"')%%))'&%("&)*&"!"&%&(+!"
@r7479
GTNAANNTCCGATCTGCGTTACCGANTGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACNGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTG
+
$'%'!!%(*"'+()*)#''+#'$+$$')#+%"'""&)$*+'%*%+++#()!")!'+#%%#'*%!!+$###!#+#$('(%'$*"$)!%%"&"&#$+$)(+#+!!#$$()*&''$+%*%(%*)!(")'&!("&&(()%!(*$"%*)+$''%)(++$($)&'')"$!%
@r7480
NNCTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGNTNGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGNGCTGAATACACGGGCGAAGAGCTNGACAGCGATACCTGGCACGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGNCAGC
+
!("++(&"$'$%**"(""&!+)"!$$)('#)$+&"!'$%#'#))!&''+'&#"+""$#!"&()'#$"'%%)#!$))*(#()&$(+#!$)*''')("!$#)!!++''!"(&$+)+%%*!"(""+$(+'(&'"#%#)*%+*"'$'&$%'*'%&+(+%&"&($$%%&*&&!)$!$'%&*&(")(#&&*)))!)'&$(("+$(!("""+$""#$+%**%*()%&%+"&#+$)"($*!&)))%"&"&*%%&$"*'))%!+"##("!+#$+!('$(&$"!#+%!)*(*&&!#$
@r7481
CTGGCGGGTNTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGNTGGATACGCG
+
+$&$"!))!#('(%!"$*%$$"##*%*!!(*!!#)&#!!$*)!"'"%(*(&%*$)"$"((#))
@r7482
ACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGGCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAG
+
#-2FEB%8?@$-";,?.3$?)&,,;2EA>-9D'878C*14!@%<+1B75=!D+!('"/&35#5BH&FD"0,>8B4C.91E"><06&"E;0E5%<2/&%48:/C:6!4>883AA=!-'<E9$*5&40=D+(8/G1G"&6;8DAD<<86:%+E3:!%@
@r7483
CTTGTGACCGATGCAACTGATTCAGCACNCGCCGCCAGCACGTCCGCCGGACAGGNTGCATCGTCAGCTCAGNAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAATGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCG
+
:G3@5#%&"E/.)26#HG*+H5HE)9E70DF1+6'6>"!@D)E9:H'/C-073#>/,$06.7C2%,8H$:)4%##8495=,*$0*D==70%.D+:;/*B"CE"*"64+>23/%A;073A-)<'61BE4(A1$6<55&81FF4.*3=??;@A2A:)#,E*-6.@:336>.!)F6A&0/!$?*(C
@r7484
NNGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCA
+
%)+&*('!%"!!&$"#!$(''!*'*+&')(+*$"$!&+*(*&#&$''&+$(&!%'$'$
@r7485
NAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTC
+
"/))-F+&''$-?9:E,2)H7.#E%4>>;H?"='94>44(/%2&'<EG8,%H)*-%+#<5=@!:.-%)"1;B3*-B&&7CB=9,7-60D:'?7@D@D;4A1#,G:('<;+4>4-1*AC3)%.;=8;.3D!<&D7G!5+D5:0D%)$
@r7486
AATATACCGAAGAGGCGCAGAAGGCTTACTAACGGCTGCAGACGCCGTTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGTATTACAACACGCTGATGGCGGCGGCGAAAAAGGA
+
#23>26/')G2=?72(%"CHC-2B.:C,7&BF1"2+EE'A+(G.74$H$H3<,>?<'*1B#)/AA!*@+3;.4E##.5;B3(&!A:D3*$4B"D"$-AFDD'61#!!+;<.EC@=69?&3;#""&5$$:@,':H%D;"1:>>**5-+):48
@r7487
TGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCGTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCAT
+
*9!EH)>';F?8"'&9$9H1%B--<&',/1D?0)A5&?G.)$E6#$+D(&F"=,8#97-H63EC5A!/664$G%1E?,9?3<$#=4>C0/#F(D#C>D!*D<(9'-<"7.<'>&'4$%,;D3%E2>*,9@8F8<C0+$$(-<D$A(A&$*07.A")(:"!1)A/!B1,G&5?%1)&6&*#=.,7,G'4.,
@r7488
CGGNTTTTCTTTGCNTCACGATCGCCCCCAAAACACATAACCAATTNTATTTTTTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTTACCTACCAAACAATGC
+
'&("$+!&!+'"!#'!+&%$'*+#)!((#++'$))"+$*)%%##(&$(&$!'&&&"(*#!"(%"&("$+*)&*($&!(*"&+$"#$#)#%'')(**%#)!#+%!"&+*(*"+""+*$*"
@r7489
TAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACA
+
8)=!8'5:5?;4,#;61#&E/*8,B4E;;+3"(>2>E*:">>*!9A<4721G:&7<E4D5D6(AH2B%#6-A(E/*@-&E.E6*>ED(%D87##0>D(D5$7/6G8"+*#BHF,-B,$(+/5+6
@r7490
AATNNGANNANTGACTTTTCNCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCANAGCTCATTCGAAGCAGATTTTTCTGNATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCAGTACGTNTTAACTCTTCATATTTAGAAANGGGGCTGATGAGTTCCATATTTGAAAAGTTTCCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATNCAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGC
+
&&)"!'$(#$*'($""*$()!+%'%++$!+#'#%"+&&"((*!+(()$+%&+*"&")&+&!!#*##+#)*(!$''+*'&($#)!*""'"%+#!'$'$%)*#*!"(*%$#%''+&&)+$)&'(#&#&!+#%$+!$(!!('#&%!($)*&$*#&))%++)!+!%+()#)&"!*&%%"("((%+%)%+*+)##''+#!+*$!(%$('#**'$('($'$%%"$+(&!+(*%&#*#))''#!(")&+$")(&!!$!"&%)')*+'$&)"""%$'%+*(&')&!!*)!*"")!%((%'!+&"*%#(*##&!(!#*+#"'*"'#&+&!$#()#*&*#+*+$%#)('&%%$#+&#
@r7491
AGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAA
+
?@20**,FH'E#3>;-E+8='*-+'1!=('4,.62*$?-"C<<3B95(.:3+>!.):2#8?,9"@>5C??@@@?3.6<=!;D=8"
@r7492
CGTCTGCCTCCACCGCGGCCACGAAAGCGTCGGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTCNAAAGAGGCAGCAAAATCATCAGAAATG
+
6CD+:<1A;,DE=00C0E4(-+((8;/)>E2:>8@*E!*D.84'3GE3?0<(C4,517F<3=.A-<=6;?0C+D68(;9<G328'+46$?E78;8
@r7493
GCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCC
+
50F(+$55@"C5F1>%D@;8F1D9!6F"?1$>G)G1!83GC,@7
@r7494
AGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATA
+
9>-F"85%#B&=*F?<B<@7..<<#+3+6&-'=+%)E<2$10H%)E#)41BD<>D@FC5)2&!6?.9-1='#/
@r7495
NGCCAAGCTTGCAGAAACGACTTTTTTAAANGACGGTTAT
+
#:4E@*<B)"27D1(C.(1:)=3$G<*7!G0E:E/;)B8"
@r7496
ANCGNCTNNTTNGTATGTATGAGTTTGTGGTGAATAATGCCNCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTG
+
('***"$%$"*&+"*((%%*)*!+*%+')*))"!"%'$##'!(!%(%!$*+%"+"#(*(&+&&%)#&%%$""%(#'$)%"##*!
@r7497
AAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCNCGACAACGACGGNAATGTACCCGGTTTCACTTGAAAATAGCCCACCNTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGNGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCNCCTCTCACTGTTTTATAATAAAACGCCCGTTACCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCC
+
</2$4=@&7@614:+7C"3::4:G:-'3"9F0+(G=D!9-#BE@@"?D&4!!$*,=!@>?*"E./&.>=0+=??%'9?!C)6.4D,?:+?$F,&3-%&8+,:42D%=/EF;3BA"2(A=B+4F)GD9B7H$DB<8-F7.HE<HF2DC,$(>?)%%F'DGF7E?>F&.'8G5B!9B=)7>#*1''(B48"&/'B&&'B&93?B(%$A?"#(B7BB7>>.2"D%/6-:0)CD*,->>,)10EB;G;5!#3BE+5=(9(A!./**:BD-8D)5:"%1D-/?57A:.B?#'A").)(C</3F.>&C1:A"-5'()(7;,1+B9%9:$59>//H*6+>A'8CG5!7#4?A%2.8"$=@&7'=):5?)G+H":2D?:!3'!"</"11%('%#:,2$(9!#6728E3!4>;0H"<.A$/+HC89<B7B7$2C>;.=3.C7841),HA<%'9()B)")B6'&>5B+,/@E<HGG9+5&*C2
@r7498
TCAGCGAGAGAATAGGGCGGTTAACTGNTTTNGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATT
+
5@%?1:;<<:..*<;#23.246*5=G"CE366GC$,$$A+9$24*#0E#<18'+&8&9DB@=3'6362B"D(
@r7499
GGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCNNTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATAT
+
@#<4+#E+05E+503%/4D!?4G2(G7<HAG:FE*D=<(,9#<#8&77">A:G*H;4'-"61A+9CA:0D=%!(-#)))?H491'!,FE.G)-:F9AF:/)%&-E;%>.7,-*G6"$$)/65
@r7500
NTGGCGAACGTCCGGATGCAGAAGTAATGGCAGAGCGGAAAGAGCATTATTCNGCGCCCGTTCCTGACCGTGTGGCTTACCTGACCGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTNTGGGGATGGGGGCNGGGTGAGGAAAGCNGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCC
+
$1&>.-4.5+F56*=58,0.;+D$@>$0H*$6#4;@G!&6#>4>%1;53E!FD4C*$*#+$3#%&/@?:74@<!C?A;!4E#;B*'=9:45-?)8E,/@16&DG<*<D4D4;6,)+C715C&B*+A8(,E>-&8C:2@:*>5##C2GD,@2&(!8C.6.7)6+&?93&E*#(C";>1=2>D6/:+0:E3=5(*'D./GF++'/;F!;&F>.H<!/A2,2C(7H,/F1
@r7501
CATTTGGTATNACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACA
+
</9A"&,"F0@56"'00)@@AB<3!=G6<$E35+;BBF'30&7)1-0261.=E3B<'5!D"A6,<9#10#<2F?%0=,$$=;?$5/98C(
@r7502
CGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCACTGAGGTNTGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTT
+
>;6!:AH762;$DC(122C,7&E%0.9HG149G%C@,'/&&1<&6<:'5B:F<14=+2HC4$H>9387'2BE271&=A3<E<%7,,-/*#<3@HC&G(0!$+58B)93(3'64<7A>7-C-"A$+0>!(;15#%H*;6?&!<F9)/=0%9,05'<FEH8B4$8<:7,/892F>25,!*;F1"G-#<
@r7503
TCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCT
+
HDH7!/+9$.C:'9'-?-4G9B+<.=:@'@FF*01)C-";D:E1EG/6)("34E0%&18-"G762HEAC)>@1"!
@r7504
TTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTG
+
')(%%)))#&(+'()%!*!""))+#$#+%!!'&+"'(&#*)!!"+))))'
@r7505
CTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGNAGCATTCAGAGCAA
+
,/F?+5>@@!BH;A6),-F@''$>'>;=?;3;'/3"@>7#31.-&C:#!<2+,H5?12B7"B-/-5,?:
@r7506
CNCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGNCT
+
"*+*&#%)#)%&+*%'"')&$#%&&'#**!&)("&"+!+)!)*+$&!!"*%)"%(*%%!'
@r7507
NAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTC
+
!/D$!-E>9>3%5;(@%<@;*@','7G)=!//4EDG?FH4,;,
@r7508
ATTTGAATCCGGGCNGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAAACTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTG
+
G>?3>,'=(?/>&#C3(0FE3)C"98F>&!+).::A:;=+-,48H)3CC2DD+</421:%$3)7,(=7!=A!0)A3H1.80466(3<B2#5*(!1C1;)&2+A9(751=1BH)=C$;24A4B@<6D*;'7%DB"+#
@r7509
NGNNNNACCCCCGTGAAGCCNTCACCCCCACACTGTCCGTCAGCTCAT
+
$$"!"$)%&&#$$(''#()*!'+&"%'$%*!%&*)+)+$#+*"#&#**
@r7510
CCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACAACTGCAACGGAATTTTTTGCCAGANTATNCCTGCCAACCTGAGTCAGTTCANTCAGGCTGGCGGC
+
3*(.*$%>9,$52D8.9:&=H!<18(;E4G/8<#-4@4.EF>5!.%?A!90!.<C-3/%&F0/>6G:!$4-'.541#3C/HG/4G>.#EC5F/)93@G+'"E%17>?!3
@r7511
TTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACAT
+
G/38'H9>8#3<AD'5-$9.@!,#5-:GA62("@)(-2/+=#<(!&F!5&@?DG,D"4B;39C.G7-#>@%#:>!A=>7E
@r7512
GCNNNCNGACGCGANNAACAGGCACNCNTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGC
+
$$'%!(!*'#%$'%!#)''*(*&)$!#+%*!$%+!$''))#%&$#!%+*"(!"%#)"'!*&"!('(!&)&&('%$'(#'!!(*"*&$'#*#!&&)%*!*$$)'*
@r7513
TTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTT
+
4;?G@&A/57B6585#/EC!4-GE@$2@8C'7*C<GAF=A,9=?(*:#&>+DE,0C*927$0EG.F1!+H6->,F26)!:D@$C148H1:FH5.G3*2.>53%H@8D,-GCC%*<.4CD>
@r7514
CGNTAACTTCCGGAGCCACACCGCTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCA
+
@C;&?=-&%*G-B'G>E1F1=A:(85F/$2;<B0H$E6%+5$!A#)-D>>;;.>5E%;:H>F82:"
@r7515
GACGGCTGGTATCANGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCA
+
=$>#AG'2D<;/%G<*B:$<,-B*:(<@5A;&F5:$>B3FF612+&>+8!01$2:$%&C?H)+20A4%@17'<.HG;266'1<0,?<:E,*"A#5&$C4<1(0D-(<:>
@r7516
ACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCG
+
<E'EH)68=-05F9.+B)GA"GF4"#436%,9*8+*<33=5&6%.F.+..83*56B.'("&0)&C666;?<.068H0A+<>%@>+D"'5-9ACF'=%?07<H<3$(&)G*EC&C&D<7(EC<F3&!()9@)
@r7517
CCNCCANATTATCCAGATAGAGANTCTGGCCGTTACGNCACCAGTCA
+
)#%*%(#)&**!+!+%(*(&+(!))%%+'(&"%+*!)'$**'$%)"(
@r7518
CCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGA
+
>8#@*'C?*&D'.?+2C!(7903=E4/42$1@9A10GH0>"&85>7("'@0.&=45!AA*3-A3G<#*H$=6B@:$HG/&B!D8+$8+%>G>.C+>6=>.0>1'BH!A&$G?-?6>,CA2*()F-49:=7#-?%)9='H.((.-A&?9EB3--'E5++;5-#+:2;!8@E*+-*'7H-26*@7"/
@r7519
TATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAAT
+
<H6#*9314,B>-*?/)6HB*@&/28B)7-<*3:9/"$AG??<5H;<9$,2&#,EBFC?"&0'<7=$=<524<"-)D%E433:'1B!:C>/?$+HB66.9'4-70@11<E<7F2"$#.C"62G!.@DB>B/E,8HDC8H+.)(64H!2'.(
@r7520
ACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGAT
+
,<5B>BC3'D<>;=46/).@F3C+53&'-6!71E"-@-)2$
@r7521
CGGGACGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTNAGTTCCGCAATAACGTCGGCAACT
+
C7H%(--FB$H'3,&+B*3DA4-9'701D42<&H3:<)=1)'33.:9/%'+59F=<(65:=FB<';'H#6@E#C/E?A1F'14G!14-8<'<,;;3H)H;!>%,@&=&0#75A?3!"E/:8<-*4@.7"3B!)9.?@:-@<+A?F$0;98G<!D%6*<2G!5-17<2B
@r7522
AGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAG
+
310A?><H&7B%?;9'(<A4%6)F46D2)*B6;58>1B2(3$>82.>'1B132G+)E8F9,217(HA2>)62#)3(!@9/7%#!C36>"0BB#)!(H:E=38,F<GC50EG<.-F@>B#E)%A$&,5%--,.+(+:91%C0$8-D!DD@$5/83=&,&EH@HB'B$@;&:>4$>%=A1D#)%$!()EF1%BC/!"",;:2
@r7523
CANGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGNGGAGAGATGGGTAAGCGCAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTC
+
$&"2%C*@AH-2*%*H8GCH!;)84<B"33:>?!",:&=>+*@H$H"*5A@C+-6%A=40A+E<*AF91-61EE--=*&4(4@16B'7+()0?C77%*.4/4&H/3H"%=:!4EA-0,2+-A4@./H->D#,8%8B;4.?(,D46,&8#
@r7524
TATNCGANCGGNTNAACAGNNGCNGCNGNTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCAT
+
'&*((*)$))$$*##''*(#!($$(%!&$+')+!$&'!$&'+%+$&&"*&#+!*!*'&)+&'&*$$#&)(*$+&+&#%**$!!&("")($'!*"'*&#
@r7525
TNGCCTGTCATGGGCTGTTAATCATTACCGTGATAAGGCCATTACCTACAAAGCCCAGCGCGACAAAANTGCCAGAGAACTGAAGCTGGCNAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGC
+
%)$+)!***!(%"'$+&)&%%'*$$')+!!(&$&"))()!%$)$$()+#*)!'"*&(&#$+")!&&"#$!"&)&*!(#!&&%*'$%)+$(+(")%+#%$*$&*))#'!!*&$(!)**&!!'&#)!%##!*!"#%(!+'%%!#$'&'#
@r7526
NGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACC
+
#(95=*3'=F9E/(0G:D'&2/$H-0FH8/7@$6"$'3/*FG,!E?*;0"/,%3
@r7527
CTGCTTAATGGCGGTGGCTGGTTCTTTAATCNCGATTACGACAAAGAAATTCTGGCTAAA
+
.2"H2!4"4D4!<8#?*%#:;#?4HB9+#>9C$!B4G':6=G.H6';**D>*)8,B!$F*
@r7528
GAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGG
+
0&D894>4HD.6='+10E''%1.)HC9)GBHD',7CD1&75@8!37?(D56@#D$$1?G&0E3;7)40A>DA3FB4-+-$7;#(%*2;"$58(;/B?56G&BEG46@67E*7B"-*9;6D?
@r7529
CGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCT
+
92#E>$"02=8G:9*2A$5)*F2"(,-/2B<;"*!??"+#-/!/3-A.@G5:=*A."2(2
@r7530
NCGCATACACCATAGGTGTGGNTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAG
+
"(-CC#EE8<EB#EA.)%FG+8(298+4/01@7>92.2F'&H"1->A?#4DA%/G0,>!6AB
@r7531
NTGAGTTTCAGGANCGGATGGCAGAACACATCCGGTACATGGTTGAAA
+
!(%)*'$'#*(%("$'"+')#*$!$"!&$&("&)%)##&##!'%)(&"
@r7532
GTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGNCTTCCCAGGATGGCGAACAACAAGA
+
<A1#0C6/.:-.3>92&&CC/!8"$>AB4%139GE++D@1*%CG7F9.-8G,'3:#H#=*4.=E45-7519.9'GCF'/+?<;%*DDC-<8
@r7533
NNCNNAGNNNNGNNAAGNCNNTCNNNGNACNGNCTGGGGANNGGCANNCNNNGGNTNGCNCTNNNNNNGNNNTCNGGTGNNAGCNGCGCNGNNTTATCANCGTNNNNTCANGAGAGCNTNGNCNNGCACTNNNAAANNTTNTTNNNNTNGGNGNCGATGACCGTNNNCNNNNCNNNACNTANNGTCGNNTNCNGNNNNTNNNCAGCCNCNCNCGGACGCCCCNGNNNNTCNTTATNNNGANGCTANGNTNCANNNNTA
+
$!"!"###!"$$$#$!##$#$$$"#!!#"$""""#$$"$"#$"$###$$!"$$$"$""$""$#!#$$"$#$#$"!"###"!"#$#$$"$!!!"##$#""!##$"$"""$$"!#$!!#!$!#"""#""$$$#"##$"!!!$##$"$"#"!!$!!""$###$$"!"#"#!$"!!###"!!!##$!"$"##"!##$!"$"!$#$"$#!#"$"#$"$$#""##"#$#$#!$#$$#""#""#!"$###"$!$##!"$#!!!#$
@r7534
TTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATG
+
/D7A*A%?$'7FH-5?,$C=#8#-:'>$=.!2'BH%,<9?<+4F-%,-C?03!$/>=@(;''2-7(+$)+F@
@r7535
CGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGNACCACGTCAGTAACGTCAGCATGCGAATCAGTGGCTGAAACAGTTGTTGNTTGAGTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGA
+
,=3.?-!<G54"A,</>/B6A;F,=$<;EH7&FEF(>(+7?)6%-%8@6*>E=2F)204<E.6>%?(8DF"8E+/*#(:>4@#(083&'/371)91@1F%$;63>3GD-?.GE)"7'):?%#B2?5*+2=1$1'7H%A3#)6H*4.E4%)!55%"32@G0?1"H/F!C
@r7536
GGATATGCTGACCCATCCGCGCTACGNCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTC
+
$&31&?<C8F50H$*7=G3@G+#@)H)+0-*B':!A"8391>?F+4F-?0:C3&G?3!)#B'@6G&+=A<C93*(&46-#5G:+C$#85$F-#1**&5F53A:7FG%D-.0-,'.C9E=>AH=GGE75>6D1+)@AD07DF&A0;@A@4&BF?=**13-H2/2CA1HA*%.>@.!+3B4%',""&67
@r7537
CGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGCTGACCGGTTACAACGGCATTATCGCCCGT
+
7=&$,#82;%:G!/8./0ECC-%8(2)BAD93A8=E-*+;;&3;@BG09<E3*%.**#'1$,*=61'G2?$013D37$5@#&9<5")60;0
@r7538
GGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCA
+
H?'*=D=9.@G*)+6E(7#*@&(""<=G=GC(1D126E:'"*<3?8<282$?H@:B"13*<7'+46(0,8,'$%#18@)6?<H4/0<$!DA2*
@r7539
AACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAA
+
A4G8,/2:5B.A!"E;G(CA7"7;5819E+#7:!)!72;*H%2'31"3H+B@<-B;8G8=#%D:H
@r7540
GAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCNGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTC
+
+3,BB.(:?3',,<"D5'4#0CA$'7-'3>93A3*C59,+=:2?+>9/!G=(>H#"&A83"&<=('+3*AD2HG0BG+)<4-E<3:A7>5#G1?'E.:;5-3G>$EEF;8A"H@29A@!@?(7/!DGD<"658&$/*/5!>E$5H;D?FAH($A&:H=778C;.:H:G$4GB-.D.A9F5#B(-H3C317@H*?3,91(&@@7H2A.;E&<8=;F3H.4:9,6
@r7541
CCACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGNCTTATGANTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAG
+
3@41F-E.GC?%G?2'*C@F6"16';H.9(*A*A=0-ED<'427>>)3=AA<0B,>.6F!)8-8!&.$3%$D//-79B$72:>;2!7H3'76C4?@=7>%2@78(E%905'0,!)<=?8C8!:8$>"DA?BD85
@r7542
NTCAGCCGNATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTTTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGC
+
!,,B87%F?*5<H#;D1?=()66C1F&FF(2:!G,H4(*>1;4'7/?=*A=<2435=G9E(GG'E0,!;+#(E<4>>6GG#<E,?-+0<7)"+C362<<*-D$01C71"*7GC-/1''-,2D#%!'*64)*&$:@<%4;-#3;*?@$A)"H%1A8()EA=,;74<D-&8G7&8B7.,9:-*G>B>8E2#8"A.347%'2%8"'6BF0(
@r7543
NNTNGACTGGCNNGNNAGNGNCAGTCTNCTNCANCTGNNNATANNNGGTNCNTGCTCNTTACACCNCGANAGN
+
""#$""####$$!$""#$!$"$$!#""""$!#!!$"$$$##!!#"!!"$$$#"$$$$!!$$"!"$!!"!$"##
@r7544
TCCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAANCGTGA
+
0!C*$FG&7H/"5>G7(7+)D01%H:$<B'$:%&C:"7<55%(
@r7545
NAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAAT
+
+*@9(?;74,<D05D17B':62//81!,,'>*@2>,%B8D<?:(
@r7546
ACGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTC
+
5'(?DG2"B!G;7C:(!-6@@"-F*B)04&C7AA..G40:<4+BA.6;>@$)7D1838GG>E!
@r7547
TGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATT
+
(725+6/52&/G,*'&>F*<(E62#46=!G=?-?,C($$?>ED!<D9E5:05EA+0A'3<(,A#&;E17977<"8D</'>42F%+D&)$A4@@&B')0#DH-(A1@/(/-A7D7@E/22<9'$9D%"F%)=#@8
@r7548
NTTTACCNTTNNNNTGNANGGCTTCAGAACAGGCAATCGCGTCTGAATATCCTTTGGTTCCCATACCGTNTAACCATTTGGCTGTCCAAGCT
+
(*#$$#&*$"!"$!'"!'+&#"'!#()$+!%#+#+$)&(%"")*"'#)$!%*($&#("#$$++##++*"**(*+!&"#"+*&#&#"%'+'%#
@r7549
CACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATG
+
@>7H+?'1$9&>2H:0$G<;/1DH"-0A75+>,9+:72H(-'@H8
@r7550
GCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAG
+
@:$(7=6E58.7%DD@E)85AE527$AGC1.H!A1:<G0=&#<#5>>$%2"81:D2-B24@='@G3?/E:.(#?=<!?)-:6&&
@r7551
NTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGG
+
(=:9?F7,""D2+653,94/A40+&&A1!0$3(,&#E.$A9?#<-:E:>(6"G;<3BG-DBA1:F
@r7552
TNNTNATTNNGGGATCGCCGCACCACGGTTAATTCTCGCAGTCATATGGANAAGCT
+
('%(##(")!)%(((*&(%&&+$&'"((#*()&(+(!+!"&##%*%!*!%(*$"!+
@r7553
NGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGG
+
!3*&"'/6;-B/<$:%+G>6#<=G?:(;A,),'!%CFB441@//GH
@r7554
CGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTC
+
!+&(+#''%)!"!&(&&$"++!''*"'"!*%'&*"!($)#+*'"*%))""&*(%'""#+
@r7555
ATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGNATGACCCCTNCAGCGTGTTTTATCTCTG
+
71:/$?421>.F#@9H=E2(.)32?,:)?>?FG1):)(.8"&AB89)@FE60;BE$0?10!<>1=>DE(&!4
@r7556
TTAAAAAGGTTGTAAATGTTAAATNCTCAAGAAACACGCATCTTCT
+
$7.2@398;,@,37H$/@/D:5G,A(7B5%HE;0?&/,1:,.=='0
@r7557
CAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCCAGCAGAATGCCGTCCACCATCGGNT
+
HHB7(&CG!!F)'6--87>!<(4*4$$&:;:,E@;<;1AA9D</#1F::,/9%GDB68B,,A7C%7)7B'.G><*#.);9H73"H)7=;AE1FE*.HA-,+;0.5D7&*'?5A.1++)F?
@r7558
ACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGAC
+
<B(@E3@B:B$!G76564#,C?1@)(-0G$%(?8+/)71H6F13/C6"9
@r7559
CGGTCACGAGAAGCAATAAATATTATCCGTCCGGATATTGAGNCATTCGGTGAGAACTTAGGTGCTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTG
+
;"6,0=/F7G.!#G)60->1H,EH,A=$1!,-)';">@3#7$<1<0G&(!DD@;.0)---"'CH#<3)$':BA4<+DC/@B('';,/-&9-H.H=(.80B:H@,A7
@r7560
CTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGNTAGCAGCATGATTGCCACGGATGGC
+
52;@><G@9&:/17.0?H9E32(,B:%53!>>F7$2.2G"A13E3'39""?$-9,F.<&<?H,'6G6='4,(*;5/3>%75-1+38*@=67B+@85#8=%H=%(#CE3E+:5$4#8-=-9(!+/DGC+%6"4,;D88)&328!5;A+;*$E$82@'"*A31>@#@H?/=:!-9".='C0##E>;-5.+0D)C.@
@r7561
TCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACGGTGCCACTCTGTTCGCCGTCAAANTGCGCCCCGTTATCCACGATGGCCTCTTTTTCC
+
12B4A91/$A)8'@.1D';(%4</;F!"%6A.,2G+C(C@(AB=&1F0<6.7-G!C*G$E@9)4<C5=<17)?=*&@67!1?11!,'1(!2$><'01HE)A@
@r7562
GTATGAGCACAAAAAANAAACCATTAACACAAGAGCAGCTTGAGGACGCACCTCGCCTTAAAGCNATTTATGAAAAAAAGAAAAATGAACTTGG
+
1<1'8AD+>51E*3">,%=>);04#'FH$"4'-52463C#5)=F%%#68$5F%$D)B:2F30'?//=+($7&?2C?HB,)'>>F2>*,H*8*D5
@r7563
GTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAG
+
"/0#AAE*;(?/,(18'.*45")BB/:';?+=HF3(5EE9"&#,),G0F;G)5,!.5H(<=E>/=+70*0>G:3
@r7564
CACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAG
+
/)8?*.'21@8=*((FC22E*$,=1"2G7B?@<2>>2<C<&C3-+/?(!F)G6;*,$24A"AA?H)"6>8>3
@r7565
GGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGAAGCAG
+
3+0;9H"!$%%F!(4B.F87,04#$D%)@3C*#@=#05=C""2!((B'9*)4+;33H)-.(4
@r7566
CAGTATTATGTAGNCTGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTNTTTTATACTAAGTTGGCATTATAAATAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCCCGATCAGTNAAAATAAAATCATTNTTTGATTTCAATTTTGTCCCACTCCCTGC
+
63#5:/-#-;!39FCE;;!23/F6:H+"FF-C9*".,@(=0=(,9=9@5(:GB!>1"2A#:A%,'*)$6B.!$'!)*.9;B',A:6*#<,9.CA;#C28%4,."E$B0;+F81+;6E8>:+7.9GD;/?D7%760>?#H59H.F.>B#F41/"$/#&=@",+DF4%2"4)60"#+3"@+$"H?)C@5-@&BF5$;6)0
@r7567
TCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCTCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGT
+
4"$C#*.H7,A1&A07C!*6@B4&D@3=D1F$E3GF>*89!-'/1B$,34819&6(0*=<4,6$D,C"6-"@C@<66'<2H>
@r7568
CATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTT
+
%2-0$"9)=7&+%AH4;'?C5<('/*:0+9/2GA+)'.>6B;F$"C$"$@H<8-DF")%1374-3&+6B;437)@3/!/)(A47)C&,A/7@7,)D8''!EC!A<-=,<6&6!+!HD'=AH@";
@r7569
CAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGNTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATA
+
95F.B?78->0H@+;C#+>7?>(450=-E$3F57#@1.9%$98EGG030,/'#6;G?973+(.C619'AAG6$H75>?!>B=8&/0/G@671%E79%,C=!7D0F+HF>>,B/=3,
@r7570
CCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACNGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGNACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAG
+
(8A+;FE+;/32?>:<A!25><%*B>77$#@'E>E'.12;,5A.6$A4'%'-&HC=6G'BB:'@@559-C#)A=CBEB!6,!$.D/H21BB9<4.(51'%).0(5$(9"!3D=3,:)B4341"'G/44!,?H16G8*00-?-7@2=@GB1-E4B="%%$3.(BA)>"H/5#42(%>7A203,BHDB3/H<5(."A,=
@r7571
TTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCANACTGA
+
6/E04<68@)E3&8HGG(;00"7<4@60=3F@:4G@@E?<)!/&$)C@'/G(0>1
@r7572
AACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGNCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCC
+
>4..9(80@,E/"0;.#+0H;B&@B79$&!D-':*/?8E=B4CC2%,>B=G4:873%?.HB0A</*5.;;)!,;@<6G!40F#7C!+,085H>7#$9,8</*;C0CC:76?A(%)942;500F9B)+-7F;&0/#,/&8>3EF<+B="A%%>3&E5$
@r7573
ACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTT
+
F(3BA2'5#@6655F=4=.8/H+(C*<7@;2,$$'A+DB!A:*0@05#2E+DH<8*$)H/;"&''?A5"4**>.
@r7574
CCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTCTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTC
+
E2$B9!#E;?8,1%$FD5836*%'24=A#"D?H<4+7(47CE6)&C!90H:1;B-G@))%9./F0&A,3#8(42G"($
@r7575
CCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTNTCTCTCCCATATTGCAGNCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGG
+
6470E57@A-A&A""7'07<H3-+&6"H'=27;6*5+-8+&<6/)0H&<)%105E"=B?7.8!G-0EA*D;2G>-1F:E":;0FBDB:"/"B3#E07@=;214%9:AE9D.,.2'';*61B7H-A2.@+24A:++F,+0
@r7576
AAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGAC
+
;#AE@7$>=5>"@"D1+%B@(A6C(*3/?G<FAF=$=8)0/,$.9/(D5&'"<+$=5FEF!"C1.#,%2;>'$>874%2C@DFG.DE)"56-*=.$A#
@r7577
GATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCA
+
)C$527D>$:C8)B.62;;CG$2:/A,,?E75:*94=H$AB%D4?F8#8!8>7@E"#8;B%,3+?;';5C;1:4%)8C2@.;GH/>3F)1G'A3353')7@-<>G6;E*0)CDD14+G!?5,B$GB>(#5
@r7578
NNAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCA
+
#!9<6HE36$BB!8-B$D3A?!:@5E+HC??(&6G489<$A2):D-1>)>8F,H,-7=/7"E2').E1,+')D2').#BH3>,BD@0$-2>GC1;70*&HB"C3)5!!FC
@r7579
TGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTG
+
H#B@69&.(+8</?D8-*F$;4>4,7(76=8+'5,7&+??3@"?8(;8#'>?#AB11H7,8$%8<E=8@B511)(*91/<H'%
@r7580
GATACAGGTTGTAAACATCCAATGACATATAGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGNTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCANATGGTTATACGGTATGGGAACCAAAGGATATTCAGAC
+
E';A:CH$(GGEEH)EG(,5(A91,7*DG,C@9:($">G2E-#7G?G@!;G=;;<FC.3?(>G%@/)$:2:<A@D/#EA-8C358'.*3:3$$C='&A3@-BB*8F4(D.B>1)*):-4652%$('4(*H<1/?<.81<,@BD'<?3E?1;,
@r7581
TNATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACNTATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAA
+
)*9C",'EE7*A1*3*B;;3#7+&B"E26@1/6*#0:$/(=1+/EGD./5-:+2=0;-@"4@%C<-/:@85##>,>@#062&0$,+6?$+,99.$-=%G+%BE?),+'=F*1(61'"3B9B:B.:;%@*?.C6E%C.$9)5A"==;<'8F*:/E6+04-B2-@B-#C1<&--E$)/'0H+8'B/>-/F"A%#932?(3A!@
@r7582
TTNGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAG
+
(+4>'0618";@2H@;E#$&A#$$FGBH0.#HF>*3<>3G"8F)*
@r7583
CCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCA
+
A':B4ED:#$(B1$G/#6).!4?%/04@))H7&45$7,*.59)7/5;>%#/.@
@r7584
TCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCC
+
)&3=.7>F$:FE8@/@17'2<!**%"?CE,*E13>%3:B5ED.0?B-!H79-99;;"@AF-(
@r7585
NGGAGNNCNTNTTNNGANNGTNTTNGNANNTTTAGNANAGNNNNNNNNNTNNTCNTCTANNNGCCNCTNCNNATGCGACNAGGGAATNANCCTNNGTGNNNNCNNCATATNCAGNGATNTANTCTNNGNNNGNTNNGCTATNNNCAANTNNACNCGNATNA
+
""$$!!!$"$$#!!#$#$"!$!""$$""!!#$""""###"#"""$""#"!#"##$#!$"$!!$$!#"!#"#"##"#$$#"#!!"$""!$#""#!"!#$!!!!"!""#!#$!#$"$$##!#!$"!!!!$#!#$#"""#!"$"#$$$#"!##!$"!"#!$!#$
@r7586
ATCTTTTAGTTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGT
+
1!F,,01E8E6+?,4?F%)(:-*!41?*4&D>((=/509E*B*@.?BFH'9D5"F/E#:H;8$54!8&+*=9!#.H3.B1+?*:('2@<+)H&
@r7587
TCGCCGGCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCAT
+
)D;9D=/8#*+4+1F-!94?>F0D*;+.&<F23?F,9:D)6%4B6)B?24.0'>&/&:G=!D47DHE*H!(6,'35%@!3;-4)?5F"'A=%:?A;4;>%*<H!C.0"+A17&,/5+%'.6*@28+*;@>A5),;5%D+=+955'@!13$:(?G!:,.E/?H?.A?F?%!4"<G1)2E*<43$!&HH!2=42$FHG%"*'%GB3G:D&(+7##!8-?))*AD2?/"(CB7$(E$A-/*2=3-6B46F&!/5>79"$6C.+!F&+1:-)#!&=D"4C@7/.2E2?&3(#':>G@-"H)+C6=F8>=H!+6H!))(ED=E<:*?61)D+%?
@r7588
CTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGCGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTTTGAAAACGGGCGCTGAAGCCATCCGGG
+
;#&#9,%E:FF;.>;2AHE("03'2CD86:43+;H=320#,@/+=G;06-(.548=2C&0-7CD=1)C@#,F*;B;AB#F+306B!('G1?>1?%8DH(8'C!
@r7589
CCGNCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCAT
+
7<,B0?(!)13G,.+#++5/EA&&<=;(+%EHF;#,8"84('+@B+)F!@8@@9?<>8>'90FD'G)9/7/"'/;9<1
@r7590
TANAAAATCTGTCAGATCGGCGNCCCGAAAACAGTTCTGGAAAAACCAATGGTGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTNGTCAGAATGAATATTATCAAGCAGCAANGCGGCATGTTT
+
)?6)@F@H#=8==G3.*83F#*E.>?)@<82D86H/4=!4+!:+$6-B9*72#(2)>!=F$6!87C:#1"25*G#%.64$9%@(G(/4&%C:89>:'6HC='D=2E9>.2=<8##=B)#/7B5-G$,(791G4&33$=/2D'33<GD7!2-88C-1AD
@r7591
AAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTAATTAAAGACGCNGTTTAACATGCCGATTGCCNGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCAT
+
+****$%%++$+&$*'%*'*&)#(&''##&&#!$*%$(*%+$+$#%%&%%)*&)*%&"#%$)'%#!")&*!)"$!(!')*($&)&%#'&'&*()$)%&&##$%&%)!!!''"*"!$"$!##)(
@r7592
NGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCGGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGC
+
$C:55)0>3@"&@9@%"/7E+1362(18E)46C*D&=GGG+,9=A5.&#<A=7A(*7:"G,*'AH+*@>$6(;17?'H!5;,=G=?3F:C'./E%&>$/:,@41?888D;=5H+/7
@r7593
CNNCAANNTNNTCNANGNNNNNNCTNNNTNNGTNNNNNAAGNCNTTNANGGATGNNCCNANCNNNANACCNTCAAGNTNTNANGCCNCCNTNGCCNNGANNCAACTNTNNNNNGNNNGTNCCNTNGCGTNNNGNNNNNNNANGGNTNGTCNGATNNNATGACG
+
$$"!$$$$$"!#!$"!!##$#$##$!""$#$"!$$"!#$!#!$####$#!$"$$"#"$$""$$#"#!"$#"#""##$$##"#""!##"#$!#!$$!!#$####$!#"$"!!"$"!#!!$!""!$##$"$"#!"$!!"$!###!##$##$""$$$"$""$$#!$
@r7594
ACGCTGCCNTCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGAGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGA
+
2/"9B$1HFF,8<53.@"?++/A(D,/=$,;>./-#&+(#7-A9E1/:<:"1HF:74CC2%$55F9<F8H.%G56'"D3$3%=:1)03!?+;.%&(F*1=G#'8$"51@'F=,C@4;'-8.B9:(?4B)/B#"):EC147:&+;#45H!1CE81;'*E4?<04,$/$<76&>6G
@r7595
TTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTNACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTNACAGTGCGTGACCAGGTGG
+
C"*:7(E&)@H/3-G2=A>,B<CC(1+>%DE;A6+7&72&D)(D&GE9.@,6?'%G2F04$1$;9/.2)E=A36G+-,+#:G35=<BE?..'F.+,86)C=*+>#!4&*+B1%AGB7>>6H!E9(!4!89:?'9CH*>,0!B#$F6H"=0D5F>)+34:3%*"
@r7596
AAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTNGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTTCAGAAATTACCGTCACCGCCANTT
+
8!'<)9>A!117GGE=#*AB0?<A'&0=>5=AB(.A-=1'/CB:,-.)82/"'39B.F82A#:@!=-<%)%)?#(72D0.H*3></,7'$1>!/933.59C%9<,B.261742&C.'E%(//#.>6,E6$**?9>6
@r7597
TCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACT
+
3&(!E($A3;(:3@=!C<.@#8F1BCCA60?05F!C;E9"#8+*4)B:-)/#%"89E4D*A89(="C>>CA$=5%$H:$%!8>9$"1E=?!967H=#3'EF"A"85@@4B5+.9%$<G@2)-&8H$;7E8E@#?
@r7598
ATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCC
+
*0D!%"B=&D5>G*%+!(B)<.;3)H2"-?6<66E*?<#;45-G%-8G:>CE2DA;&/@$@(6
@r7599
TAACAACGGTGAAGGTAGAAGCCGAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAA
+
#;97%C%@;35A1"4B*F215E(C8,)-&H:0$G!**88A9+<E*>G,=H+.--+9'B>#A=$*-6,5/0@)9.FA$
@r7600
ATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCT
+
/!!;3@8*&@&-(".7<B3*;H&?(%D-9"20!92>(54+9#93A8*;)(#EE5<-
@r7601
NATTAATTAATATTAACNATATGAAATTTCAACTCATTGTTTAGGGTTT
+
$FHF3/*..*AE&8%:D&:2>D&;*1@>=3%"GF(*A#1.5).13B)/8
@r7602
NACGAAAGGGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATAC
+
#A@<;@0E#44(2/0$%1!,7?A&)7;2G+%9#!+15;::5=*G(F>/200G2&54E0ED,:CG&5!(
@r7603
CAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTGTG
+
#C+@0B':6*#8"G:1,#01(0%34A12>::8)706;;:;:?&?<$'H<=89@>4<5(G&+:/<3F3!.G)"C+9:B:*03B=)2$D35=3<$A9!DHA4)%(8)'B"F-1F3%50-835>CE(8%,'6E%C1(=),F62E8=*FGC8C/A4=&7,;.B;@
@r7604
CAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGT
+
,2=#=8?C3G7,3;-.A0@+H,C%9=#'8-&"!+C+&6G&/>-6*+&(?H&'6E.
@r7605
CTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTT
+
(E&7BF/H&<DD,;2'GD/-C(#6'0$B,)F&>71$".-H""
@r7606
ATNGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGG
+
$*-C?9=DD+23$BF)-+/*(0!?.3$'&@@9*;E(.G".$!B%:'D31D@:*-
@r7607
AGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATNTTTTCACTTAATAG
+
<'%&"G80-@D1+#7GGC#A("4;A987:=,@--B;CDBE@;)DCD@6G1;D;74:&7:,)+&5&.E1CD0<,-=E""*4;H==,<#00H+.'E!6"4#+2F7%H1&G'9"FD;8&6%*9>.4G+.G6"".)@E78)3F,4&A7D$-.G9%"726AD5!''9;$$($D*/)D.#$22170FA.9A;(*E5+H;;/?*(;F%2!5G)#@=;:!+':@"3B$4"%$=!DE#07H41CF(+@@>'*@1B%C3,;?=871B$72'<=#8<031H-1C.-4>D@5ED!D'18B0><+(&?>246.;A<&8C
@r7608
NATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCAC
+
!FB>8?+,:*'0/F(B,-%G+#7(%#/)2;+F2(63EG5;4BEF6H8A;:7/;9
@r7609
GCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGANGCCCTTTTTCAGGGCTGGAATGTNTAAGAGCGGGGTTGCATGATTTATGCT
+
AGF8:.HD%)"99:8<?<*D,707<'A'&$9&,HH=/CB=H>CBD).!+B3%"81"B;E=:4'B'A2($>"B=)?!?/:BD$$#C@G7.%;
@r7610
NTTGCCCTGCGGCTGATANTGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGNCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCTG
+
!>9@>,"-(2:?>=5.18>$C>(204B>&0-2@.6C8*B%)?5H88?(<<!F1B7%;($1+=<9B#8593)4*-441E/G6#%*='!?-5$=B&1,0!*+(6&9//2%E;4:'&<>7>;*,E1-)@AH;CD@)6-7-4'+D'721H,:"6'&)A-0?12*##F1"@6.>&3'/4%?/#+D'AHF@-3A3(+44,#&-,41.B3H!@%1HC6!*9380H3G461;,0/77+B00;E@F>:+$C'-47*=H)7('3C+75333-9EE-?&!G"-5+0@232*.(@CCD-)H1@"!<A&.1<"006)1"?);3,
@r7611
ACGAAGGGGACGGTGGTCAGNTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTAAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGNGGCATACCCCGCGCGAAGCGAAGGACANCCTGAAGTCCACGCAGTTGCT
+
&+#)$%%+)&")'"%(!%)&)'&+&&!*!&*+%'&&&))+"'&#'%**#'("!%+'&*)#!%"'+++(&$$$**##"(*#%!+')"+$%($$)$*+("*''('$&%%)$&+$$')!%#$*"('#*'#'(!%$%'!((%%!(()#!*#"')&&+)!'*$)*'+")%'#*&%((
@r7612
ACAAGCCGGATTCGGTATGGCTGCATTCCGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCA
+
)>!@'82=;3G>=?EC'?&"2+#3;$8"7F40=)<&C35$012/E>;@">)D@;-9%.%F-;4:'!1&>8D-<=/::96);<,D#8>!*'C)2C'8F4<1%F?71GE3-/*DC'#8+6G4?C;*A,%A/3H+<'78$.H-.@8C4EA+"%G!44)?A)"'4:&>D%0.:C3()2B#!0BCC8#18BD@0E!,%CA1$:%GG"15*:2CC#-D=;B:10;1
@r7613
GGAACAAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTANAGCCGTGAGTGCCGGTGCACAT
+
51'273G9&./)2/'AGH05&/B04*E#4<A5#:*:5B?)D(F@AA-H-(*50G?&*%,//C=3+">):B@<%@))1,""G-A+B66;0)=&,!76G2-
@r7614
TGTTGTTGCGNTTACCCCAACCAACAGGGGATNTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGC
+
)(%'!%')*)$($)'+(""!+)*+'#%*()%"(%!('+)')!###)%)!))$*%)))&*++!+!!$$'(!""$)#$$#**
@r7615
CNNGNGNCCNNNNANNNCTGNNNGNNNNGCATNGNTTGGNANCTTNCNNGNACNANNANNACGNNNAANGNTTGNNCCCATGTTNNANNTGGNNNGATNGTCNNTANNANNTCCNNNGNNNNNTNGNNN
+
"#!$$"#"!!!"!$#$"$"$!""##!#"!"!""$!$#$"$$#!!$!!$$"!#$"!$!#####"!!###!$!$"#"!#!#$"$$"!!"!"#$$!"$!"""#!!!!$#"$#$"$#"!#$#!"!!!"!""#"
@r7616
TCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAA
+
C"D&<'6#.8.*'FH&*A#@03FH1$.F%>F1GE!'26%8B'+C?"A@878?,'A1%557/81(:#B:/C=?@$!DH:G(5..7FH)6%G<2"$7ED)8?+3D60-@70?=@#$A/5F/5,EH/;)("-14
@r7617
ATGACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTT
+
4*:/(;2E=?)#H/8B!A'(5(55D<5@36730")?<#">+2<,E(?:>(8>98%7)H5(<&1(+1"95C1@7C7$7>'5<5*=)"(E3B%)D,3/+FDA*1(+<,/F54:!+)AD"4B9*59H+94,&FD@1:&,1=D/:B2!B!GE+9./$=G=,%F,9*G/$F,+;)#0>DE312FE'.#H!45(A%E=!<&D<6%B(D!!F*30$5:A0F$,%(3B?
@r7618
CGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATNCCACAGACAC
+
*6.3G3$?$)FE9C*20@"#$@%35:&CB'*0&298<97A46A7$E05,*:6D3C3@*>"@.?,'(1C$/A*!<2?4ED
@r7619
GNCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTTAGACACGGAAGTGGCCGTAANCTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTC
+
%"1!$EB@-/9*:2,&'22EB*124"+'B1#+H9;1H3@C6#6.++-(%!7;AA7$(?2118("<E8D5!8#*173'&(?@031%F)>5<)0/191%CE=CF&@G-??/1#=
@r7620
GATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTG
+
0+&0'6C>*HC(:0GAC90H+'6.528:E:(DC6>0=>"7+C'B4@%@=50F7&A:B1*E2*$-$;(0;3++>F#%"&EA0@CF-
@r7621
AACAGTCATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGC
+
>C;56;?4'73.HD(A1>>::-7*A759H<=A(?HA3+)1<+=GC%)(>H+;-167B@/=.0!G3
@r7622
CGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCNGCCAGCAGATTATAAATTTTTATGGTTTGTGGTTGTTCACTCATTCTGA
+
0,$?31F<*1>B1'A.19%:92&<4A,?/A-*4@56$1&F/&A@$,)(2087E!EF'B+8E%&*6.;7"*'5-+9E?"7G917-HF@<B%%GB&::0@..'$
@r7623
NGAAGANGTGGNGTGTANCGCNNCCATGGTGGCACAGAGTAC
+
!!%(%*"'$(*!$$&'*!*$)))+&"&'(()&'&(&!*&$(!
@r7624
ANCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCGGCACCTCGGTGGTGAAAGG
+
5<)F@C82'.D?38:)0?E%",@.BA4<25,F8,<-=G@G1(A"3CCC9>#!43F'F6*?@7
@r7625
GGCCTGCATGAATGGCCTTGTTGANCGCGCTTTGATATACGCCGAGATC
+
D!#F8A>#"1B">AF333?G<)%@1D;8(G$"(4+C@C32&9BAB)>&)
@r7626
GATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCANTATCATCATCAAAAGCAGCAAGTTCNTCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCNGCTTTACCGCCCAGGCACCAGAAGNCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCNTACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTC
+
1?58:(8#/C?>)0C"#B0(#>#7>7E6396$H)'!/)F2<!D+2(%A+A:D8/&3)($9-77A9,#A$8)>'$D)B9&?%73*$=A''.346CE>)G3B5,:-H6CF;;<>8=43&.E7:9%!<9G$41=EC-5?,14E0A"$4/8;<-@4C4)/,'C)G05G'FFED6>51=7ED-&5>&!A##F*98.:$%."4;$E0+=%.(D@G99$<3,"H-782=5,AF',*+;9#%1GEH;;C8D<4#?,,><(8-46=2;=5=#"HC3,
@r7627
CCTNATTCTCTCGCTGANTCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTANAGTGCNGGCTGAATACCACAAACAGATTGAAAGCAACCT
+
&""$)++*+&$$'!+++#$%('%'+%""**)#"((*)#"*))&)')$#$%"&)&&)$#*"*'*+')%)#'!*%&&*'!!%&+&'""+*((*(!&+(!)%***+&*&!+
@r7628
AGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGNGCGGTATCAGCATCGCAGAGCNAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGNAAGGGGATAGTGCAGCTCAGCAGTG
+
)-8&7>A897766<3/B4&$=H&1+$$<:)>8CC+/H<C(+&4H&G:(B*2*,6822*)0H<:*2#?%204&>:2*&<F$'HA2F&!%3?<,#)<3CFF05?!%3<<=/,'-<E%A)$#G3G&8?2@/:$;=*D,".:G!;!;2$=:G)>%!=,6H"#DC=.BE0*!6-F/F,D>96E,:=719A>$%-AAH@H+4#F+-
@r7629
CTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCNTTA
+
-5@!G'?BBC3(G(6E38/#.>.?5=<)C=#%A-17:.@8913C&C@B#*8""7969;HH";6*,9;/@-+,AB$0@H=(:"&=A(2?87!?&+4&?,16%G/DFD6'1('D$,=$!690?24095.*G7%50B74HG%5?.B7,8+(564(+7D8+=D(0C>E-ED1H$0"F%!
@r7630
CCNNNGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGCCACCGNTACG
+
*("'()%!+"$%)+()")++"'#'&!"'""+&*(*'"#$##'(!#'!'%*&&!&(%"%))'%!'*"#')())'&%*
@r7631
NGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTNGTCAGCACGGCCCGGACGACGGANACC
+
$$D1;!@;(>4B)-#$;0;;>+4-'(99>''-:0D8:)AGB9,"7%<B#>94<+%H!*4H6C9**A#6D?F,/E<:.6%9FF//>*=>@353":
@r7632
NCGCNGAAANNANNNCGCGTTCCGGCTGACGTNCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGTACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGNGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTC
+
"#")%&#*!!%)$#"**+)($+*$(&%###'%)!(#'%+*(!#&*'&&!$)#''#((#"+##")"$'&!*($*)(+!#"$%%)$)$%#&&!'%'#!+!!)&*!&$%%&'**"!&$$%)"("'&$#&!#+$%+&&'*$$%&##+((#%'%!()$()+"+""+("!(')!&+&)%%&%+'$#)*&&"(*(&#%%!"#"'"((%!)#%$#*$##)"$)%)%%)*$+*!&(#'&&!%'%(&$(*#)$"%#)(&(#)#$)"$%*$($++$*###"")!#")!$)'*'+%'#!)#)%$+(("##$)#)("&+*
@r7633
GATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACC
+
5(45:7.:64;!;1'*5E0(<-&>,E3$$*%B7B='9B6GD
@r7634
GACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTNCAAGAGGTTC
+
A+"7<B;&@.8=35#$:,F#2&3C%@:*!:=2?//F.'D#266'";84*(#230"-1B>G.:3DC/.)8-
@r7635
CTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGAC
+
A#"8;-=)*D"/>CGBB616E00<2*,8C&=@&!B5&,2,:/68!0H4'D>';B$4!+!++:'23HH=H>%
@r7636
TCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTA
+
DA);'%?*$,'D#9GF/7>(F:5#*&'.G8/D!G<1F):&(.8D9D(7
@r7637
CATGAATGTTCGTGCTGGGCATAGAATTNACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTT
+
=*/C=,,-+C;(1E.-<C5*7*C11CD5D<7)04,4!0A263-E>E>"!*8/7)C(2&"57@+<E8H.C!;6%''";#
@r7638
TGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCGGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGANCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTG
+
B%44--<493'6E68-,A&&E;G849'>-B8?!">8'E-86;#D,D/D,B2A".=-3H9A$(HF4"@>*<,,!,?+"H2/2.(811$H4%:6,A%AC$3D$*6A#3+;=B:?'@(4%(H0(-2$CB+4!6@D$(,?G45@:0H$5;A%1A95#)<6H44;"'A5=<<19+;?,?;2G"E689*7'5G!@%$H<+9-07.%C3(#0#E3%);0'!ED!A+/;AA<ED*'"+>/F,;HB"&3?A-@:=4'
@r7639
NANGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCC
+
!(","=C=#CD/0>D,+>@<C&8F(6)G!%DD$):7(1.<9(4;;2:*FC
@r7640
CGNAANTAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAG
+
#$#%#"()(+%"#"#("!(*&+*'"('"$)$$#"#*($+**'!')$""')!$"(+)#%*%'++%+%+&!!&%+#(*!$+"%(+!)*)+("(!$#)&#%&(&'!*!"#%'%"*+$''"
@r7641
NAAGTTAAACGATGCTGATTGCCGTTNCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGNAACGTGCCGGACTTGTAGAACGTCAGCGT
+
$9B?*%1%(D".90G.23/1'%7'#'#397"=6&(!8?B2@,7-$10"F#<98$%!C8*DA',<1F-"E@*-,%G"!+1/70!8?(#)>9C6?(9H#.@/:@7F8=H%<FF64(4")*$9,CC$
@r7642
GCCNTATCCTCNTTCTCGTNNTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGNTGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATG
+
"&&!%#'(#*$!')$"*!''"((+!$!&"+&%!"*+"&%*)&)&%&%+%&(#!*+*)((#%)&!%#(+'('$&!#&()!%##(*'*(*")*)!('"$&#*)'$)$#(!!###)"&&%&+)$#')"#+#&)&(')
@r7643
GTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGC
+
7;A&G@"/"#'>4/C:.&+,-*"&37=HA<2-F2@*-876?<#E,6C3:F&!78;!AC
@r7644
TTCGCGCTGGTGTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGAT
+
9HC&'=E33090$8&,(FB3#4#G4G8);#<)&&8>2,)@))9>%&;2/,.32""0@")9#-14(B)%#%+(A?B$?48)5!)&6'222&0E).4A@3GD,2(-H)F35$H%@9=BF%)"C-3;=7/;28AB"%F8+8#()$@H&8*C<;99$H!/B/>%H)$,",#EC
@r7645
AAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTC
+
=#=+G!,B?4;/DF(B/%!F+&A)8988F(:2'9$>4C;)(G3:>.6&8))A&$AF5,872
@r7646
GTCTGCGNATAAAACAAAAGCCACCNTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTCTCCGG
+
782B/?GB%9FG:1/(?:B>129"F?E52@;0F58A2H-'*GB@4#6<,1*8@350('880%A=(GD/B0<<3'@-78960!-@E0B3G3#H63;12AH
@r7647
CGGAGAAAGTCTTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCAGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGA
+
B=(9*E,?9+7(FE4%:#51&+490C&$355'<E3')49B)..2E<!!2C"@.FE"97=8D=!G?G9EBBGH4"(;+?H:8*A(F9D%(07";.-2*&$=95!4&5=,;*#,"E:FBC(E:<3@+9@$C6,B-&<)
@r7648
ACGTTATTTTTTNTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTAACAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCC
+
3$0('/GBB<7C$&>?42$=!;')(4C,@@%/BC:#-E1=3!7:C+*8@EH:-">#3/+@H/,<F'$.1F!,&9='GD-8".=#H#,*<A=2");DG6;68=7A)?64;DE0%=7>>6.2(83(<?6,
@r7649
TGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGANGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCNTGAGGAT
+
0:*-??,).&G27&<B./!*GF2D0"G8@7%G=$8".;8),C4.B%959>D!>696-C#A.?32C!FC3$"F@*@A)-(F9<3134%G/A3><@5+1F
@r7650
AGAAACAGCAAGATACTCAACCCGATGTTTGAGTACGGTCATCA
+
"&G@1=,@/9A0><:<F?6&!"'G=7?A""6+FD,:>;*=(F27
@r7651
CATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACAT
+
)C(@9GC"@9DG$B4AH8!1&DG9H0"='4E@;%0+2E)@;@#0AA5>36F<1#A+<+8<$:&F!#@!/-&/@4415HA"+6F*,,(4+2!G$<18A7@B53(.$/1==E@C$#$..0*?8GAB0D:85#&E67:D$="!>E-EE0E&!#/7!/!14*%%>=
@r7652
CGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTA
+
(H(F:.-%FD'@87>G<CB05,0.8*D;%&;9H?G0/8-,=*0(>%!*G%?'B+?&'<?
@r7653
GGTATGGGGAAGTNGTNAAAGAAAAGAAGTCAGCTGCGTCGTTCGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGG
+
'))"++&'')*&+'))+%!#+)#)!'($!(&%"$)(*#$%(!+!$)*$!'*'#&+#+)+&#'#&*!!++#%%$&*++))'!+'*!$(!
@r7654
TGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAA
+
4+%;DE@!G-'"'<1F'*<B@05A3+G;B2A?31.$/"0:D;(BC<*<FD'CD)=."DE?$/0G
@r7655
GGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGC
+
?3A)@BA,43#&CH,4')D=2.A8/=9237FH0)3'E8#0H*..A@A6<H5>,*!*4*=C:#0?3&;@C7%/)@F
@r7656
AAGTCAGCTGCGTCGTTTGACATCACTGCTATGTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACNAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTTGAGTGCGACAGGTTT
+
:/;?F,;7+$$<+FB3>>'8A90(:<8@",&,*$E??6<C#);"6+>$515.A>:!?4=0G3A$"964C(*/'D*)4::8;6;4'*65!B@:?.48E)E"-664;*"3-8A6C#/@*2=C4(&+
@r7657
CACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTT
+
*/9-;4";#-D6.;='7==)F4H4"GH6824E#-A@G@/6*7,8/@<
@r7658
TCACCGGTCATGGTGTATTTGCCCTTAAGCACGGCAGAAACTGCCTGCATCTC
+
GG-0-&H$1)*:#->'$%"9'A8&,DG$@E,$C6;A8?=:HC1,=82A,;8"H
@r7659
TGGCCTGCTGTCCCTGTTATGGAGTAATCGGTTTGTGAAATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTATT
+
1)04%>#.FE0:7:(F*/07;'!A/'6=+A#(=5-#A7/'=@"7,)8,>',>0#>?("?*>3EH''HE84E6(=4D1"C@!,22G%3,<99$2A<)+6BB(6(=9?H=C101%
@r7660
GACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATNTCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCAC
+
3D'-?A/655+7@C+8$%?(#EB,;4H)@.8>>H?$F-41)4&D*?#:<6&1%3=!05/5-B0+&*3G$<:+D9@3@=040@1-/B'1:<&65:)$E6F@=&#%<G';H2+16$9AB=-F*<GA5
@r7661
GGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGNTATGACTACCGGCGCGACGATGA
+
8/?!?(7!F=?BA'-61%E#4:6,E(5%D@2=E.,H?,?D,:!89?+.G&B19+6!%;?AF->
@r7662
GAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTNAAAT
+
41:.3:E"6C.7@1&E8)9?A'$4''>5$D(+2F,>68:'<#97+?"=+=H,/*C28/=#G=5@A)?.5,$$@
@r7663
CTNAGAGGTNGCNTAAGCNCNACNCCTGTTTCTTAATCACCATAACCTGCACNTCGN
+
)#"$&%%#!!)')&#!)#"("('!*+!%"'**+($#$(()&)++'"+*+)+'&)*&*
@r7664
GTGGCTNATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGTTTTCATGGATACAGGTTGTGA
+
!+!(#)")"#"(#'%(()!#&"*#%*%)$)%!'%+%(!$&+$#'*'#$*&)#)$%%)#&#&&!'!&'*
@r7665
CNCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGT
+
89#(!869$.=76/?0$899"9#;)!"BE.72G08G,"B1:!;<<A:$A)-1%9C%05?F(-&1F$H,,8."0!).EA>'!3GE"E-++?3$G#!/1:%+C;H$73:3B9@C=E=:&9'*(H;=+75+%'5=7>'?!,20>27D/'.G1')H(-8/&#"&
@r7666
GCAATTGACGGTGATGTAAACACTATGAACAATTGAGTCATAGA
+
:!AD(4+C!1,@,+&.:$7>6!8C=6A#=G87</6&-+?%*>:7
@r7667
NCCATCACTTCAGCATCCGGANGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGCGTGGTGTTTACGAAGG
+
#3HA-3&G!7!F3=92G3DF#'E0+38>7@F2E/<DD%C9A6*@)==@'%(;5)B-@&=.?C5EC6&;*'GAB
@r7668
TCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGCTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAA
+
-+938+$C/;G'=9@(-"1;$;?#"<+H+C:>/:&%$%FD3,!C;-B<"%*5G2"H-5"?7D06<2*#F!*2BB8=968B'0/;.;;.41,B$75@G44>=$A8!H&),9
@r7669
CATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGAT
+
*;&AE9!!HB**"6=0-;;'*:/H?G##3?+EF2B="(*AGG7&:D!.478?36>FCA#<=D;*CBFG,899E$3@&4D248D2=7.BH:8D+(B#=H+:17"+'H+E(-.0'?"&;A.&*72(/?
@r7670
CCAGTTCGTCGGGGCTTTTCCGGACACAGTTCCGGATGGTGAG
+
?#D2F'8(G.F<F(!A2C2%@5A28G=6>88:&H//7%"+@;3
@r7671
TGNNGNTGANAGTACGCTTACTTCCGCGANACGTCAGCGGAAG
+
&""!#!)%""+!('&$$+*$+'%)"))((*+)(!+)#&"$)+"
@r7672
CATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGA
+
>+%-G28,.67@2*-9@2@1$3D:4$A#;B"3E":9>@"=!<"#A1H,",8,;-@<D@&DD(>99,
@r7673
AGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATTAGCCAGAGTGTGGCGCGTTTCTCCTCTGCNTCCGGTGTGGAGGTGGACAAGGTCG
+
&02@=&F$D*<#=A%E*2'G00.F)+<39"*?$2/)G'")E"%!?("B3&/%1H22*?+AH<&<#9AF,;B$0HB/?C&#5.C*62!HG7&B+
@r7674
TATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGG
+
)C20F9@69B="E(0?+.!"?81'<3G4=>:8G:$6<+=<-(:42*?$AHG'"F'':*E-C1D#28%2<)4@87E07+%E,BCAGH..<63H3H$%>C/-12+"8;&,AFGB@,B#+H0?>#?H@=))$%=6C2"-0<E*GE908E:;2!"G*:B
@r7675
CGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAANGAATAAAGAACAATCTGCTGATGATGCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAG
+
5&C6E$?/>4F>H$!3D0G<D)2E%*<48'E"2<-*=#/8'?!6>0B>22;.<)G+#40>G7-;=CA/2-H7H.93C*;@,@%0"G6<..%57"9=-<:?-8#8HA/71$%2BA28)
@r7676
ATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTNCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAG
+
+(+#%&$!'(#'"(*&)+()&$&*))"*!+#)&'"(&)*%)'"(%&'&)"#%%)($$**'%+*)$)+(&)#!"!")"%%+)%#!)%*$!*+'$+*!!())"++')#'+)##!!&$)+)%(%%$('$+*"''!"+&%$
@r7677
GTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATNCGACAGGTTACCGGTGATTCTGTCCATTGGT
+
5F-F5H$1+=!'-.2/1B-):F1.=!":>#GH8B9&GBE@DH#F1G!=*H"A?:"HHA7D#?GG6"A!F("DH7B5-(#$!GD8,83F54>(*7((+F8#HE5.0A;!*/"$!/:7-,0G"!G2#'1<B7GC495@*!!(;D+B'&@#1,06AF*!B7<
@r7678
TTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGANGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTANATTAGTTACACAGG
+
G6&:.@,-$&@=/3E>9/?<";B#B=?/$E@)D2D,,3,?+B"C95/E(.#-G@?7BE5()H:96<A&1FF$G3G0G.H6A$@C78D:F+03&9#$*9G7C2G(1,->?HG/(=H,4()>H>09(:7C91+$=>D6"!A36/B';%+<525*9*@G1//
@r7679
GCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAA
+
;.>6.3-*9$>+<E?>B3=5"-(3(?0)?+?5?E:)/,-%)9)GC(25<)A.#AD,.G7H0-/'5B@;-@C/GD+>D/)3EE1@$8B"2/,H&9CH"42)-<$$99B8<%&7&/H)!<#/)G.2E$'B&!*>5.F@=61CE21?2*<-4?
@r7680
NGTGGCTCAATCTCTTCACCGGATGACAAAAACCAGAGNATGCCATCACGGGTCCAGATCCCGGTCCTTTCGCAG
+
(+-2=D&#=#@5HH@#(,A0?4&&1A3.)ED(6+8$,24'<H%-<&HF0AA(;E5:A=6=(,0&--"/(:-3H/7
@r7681
CGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTG
+
)")+#!!!)#)*"(&*#**+"!"+*)"##(#!*%"#'"(!#*
@r7682
TTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTG
+
'D@"=3.;<H+*-@G#3>&:=/)G<8-728(E@:%!AC6+/-(BD)E$%!16H-4*:$4HH'!;#-*<)$+HC;*'B;1B'-/G=1G4)((B8,@%4HH
@r7683
GTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGC
+
1'G-++@!+%7,-H8(.56'19D*C7,E*1"=//$13$0?3H#A;3!(/E=09)$2@48C*9/51?+G$A!01C$-6>GE8<C810,'*B*$28CA7)HF0D3-
@r7684
CGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAA
+
H-""3;78(-:E2(&&D2D35/&@,")$0!"A-E@'-F'<,)4)").-9$E3>H)#@,=2(,G?0<,76*F@89:&,@G66A&6%42;0,#!;5!%&?>%%8"!=)H7>>E>&.
@r7685
ACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTA
+
B?A8/(24/2H)#($'E),D>,44E-"=%-!8.<-9D371B+;//D.@%8$$
@r7686
ATCCACCTTATGGCGGCCGCTGTAAATCAGCGTGATTTCCACACCNTGTTTCTC
+
<$/F@2;+08:GE:.599!F6C7'A+D%D1"C6))'(<!>,C+)C<GB%=(919
@r7687
CTAACTTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTNGAT
+
'*%!%"+(*+*'(*%"+"+%!)$$&$+#!))%)(+!'")#%#$%(!$$$)'%&")+"''%)+'+(+"+''&%)*'$'%+%"+"!!
@r7688
AAAAATCGCCCTCACACTGGAGGACAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTT
+
:@?<42>ED&$/H@'5AE/&@8+2<3"H@1((;:;1H2:0+4)#:C/*3G"2C#",C@=0-)9,3HHB0.8@)!D1CC-+=E751H?8>3'G;"@<284F1H0%''91+D)A>2!)E.H
@r7689
AGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACAATGGAACAGGTTAA
+
??E(<10*,#G0FB;;,145,.B8$,&AH-+F2/=5D5HB0B,%4/A&-?-G
@r7690
ACATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGA
+
#:)3C#"<9=%3>2*('5)0;F&$;*!!(9BD+8*E952:'
@r7691
TGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTG
+
*#+%)'++"#'!&')*$'(#*($#!!$+"+#!$$+*+&!&!$$*"'+((#(#+)$"*"+'##%)+*%(*)#)$#&&"!$!!#+)(+))(!$&*
@r7692
GAGCTTTTTGACTCATTGGATATAGTCATTANGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGAC
+
83.#CH@2.<6'D/7=?E/1HC3"4GAE7)(=G''',DH;<<?G)=/%B%F56@%(;EC@C(1D:34D"CB.":/-.&54GC(6CG.49;)-.G80G*.+#03&0
@r7693
TCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAANACGTTCACGCC
+
941()E%+3CA)+2%0&A($BG;<((6B"56G%.5%5.9@<?!D?6@,*>=
@r7694
AAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAANTCAAATCAACAGGCGCCGNACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCNTGGCGCTGTACCT
+
:/C!$3/38D)*$"'#D37("<2(5;@CB.<0:31/!&08#FF;@B7E1<%E):'$-/AD0F,;)6$!B,&;?A,CB/!2C/-.=3;")<5'A3;D5F)"&$=),:7"<8CF916%*=8&G=0)@&"=$!%#*@.F<(?,2B!12D6%!G0,1%F&:H<:>CD6+/#A)B2:D+%?G/#=@30/5'@"2#,9++"++:<H##-FD42@B6'&4>B6EH:#D32=8'=21$F-
@r7695
AGCAAACGACGATGTGGTTTTCGTCCCCCAATCCGTACCGGATNCACNGGCACTGTGGGTGTGCGACTTAATTCCATCC
+
(!$+#&"'$"*$&(")"))&((!#*+"'#&)&&!$$#'+!*+(#%*"%+&$%(+&#!)($%($+*#')#*%"'%&'"))
@r7696
GTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAA
+
*89#3>7:;C!.G4F"B:,:0+')>()19.-#-**@*-+'=&<*+0))7;;%6
@r7697
GGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAA
+
)+"%'%(+''((&$#&)#+$$'!(%!"%)#)$&$#+""'#
@r7698
CNGCANCTNTTTCCNGTGAGGTTATCCGTTCCCGTGGCGGCTCCA
+
$*"%!!!))))&&(('%(%)+%""%))+"&*%$)%&+((!)*)))
@r7699
CATAGCCTTGCTCAAATTGGAATCAGGTTTNTGCCAATACCAGTAGAAACAGACGAAGA
+
%<7=.>0939$HEB@<<+'&F((:1"C$D&"E3=>G==:-=H,;7+.H=>,(?FBF'??
@r7700
CCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGT
+
.;:$C$=*DA-#HD=5EG6%,/FC&'0B-F82>6,=/!=5/%5E*.862)%8,+<@;?"E#"?E%A7$%G+:A!H?$
@r7701
AGACATNCTTANTCAGCCAGGAGTCCCCAAGAATGGATCAAACACTTAT
+
*0(9A2.<!*1=%E4A425)5F4/2:<H+;H'+B>,#'/26%:,'!:,#
@r7702
TGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCNTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGAT
+
(4#5=@%E=+0:-H<@GH@$>05H+8./.CA,13-91+0"=9?3")-2'A$.-,(G@1GB$D-20:"2+#;A94A47*?F,>;.&*>=,)*/55*E?#2B+>)<<>/A!-/!86/,%/F73E9667<!%4A
@r7703
TCTCTTCCAGAAACGAGTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTNTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCAT
+
$.'>3@9A*%<<!*(7=/5&(7F,5A7"E+<54G$7-6:F9%5G,&G!?,<0?H3D.HFC,%"210==$(%;2(:(7=($A6.C)7E394D?52<8>,7@:==):8A3;'&63?
@r7704
GCACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGC
+
"=-;#FB3!2'(<6),9?B#);@''8F>?,56,<FF,-C;/5AD+)F6$-'?/3),29)-+)::$D#
@r7705
ATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACATTTCTCTCCCATATTGCAG
+
$;?E92*%D#0""B<4#"6C8D3(0+HE*8%+*4:115#>1;-)*"/%)!)<'-C83-+:"!"8?>=
@r7706
CATGGCCCAGGTGCAGCACAGCATGTGGCGGGTGACGNGAAAAAATGCCTGTTAC
+
-,)BA'G$G+>F$7!AFD'"#7!)A(DCC*1&?1!3G-5-&2C<9?/D=5'(!(:
@r7707
TGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTNGTGATGNCTATTCTCAGCGA
+
09)<9?,->>C";#;6C-GCB9$'A1C=/&CD<D9E9,'H))C!)%4/"5,:2HG?
@r7708
GATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCCCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCANCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTC
+
B#@<?55,2E+$/;)70@EH-50!49E,1D=74</29->8-B&7A@7%><:,4=;*;97/!)')0A9(!H"7722+?:(49,+:%$#+9";>B$)C<'()&%:C4F7)?)8B=9*B)!9(63%%7D&)G9=7$09A-5@1+0)D=(B=A:*'*F;1=E$?"22@9#5F(3>9D-C9&13$7".9/8,6%B3AH,+:E0H?/A3+.6)23&C>61D#+$,2=?G4.E%B3,2)1.!9%</<6C@>9@38,:.7%8@2E;,D'=<AD"FEHDEC%,@$&DH?072@,A4#.<8D24=A!
@r7709
NCNAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTT
+
)+><$-=@/A%0B<9/57)7C&A3/%('%G&4D,"=+7.;B5H6FAF7'@8
@r7710
AGGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACG
+
AB.E4/1@.2*24)*H"3897E79#(.8!56@5.273.:(&66+B:B9;G+4D%*,+C05+6E(2,;76:34F2D#";,=!:B*EAH'
@r7711
ATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTNAAAACGGGGGCTGAAGCCANCCGGGCACTGGCCACACAGCTCNCGGCGTTTCGTCAGAAACCGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGNACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCNGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTAAGACCGGCATCCTGTTTTCTCT
+
F=?C83HBCF>1D-+19>@1>)0+%+H2=.4@7'?2.)6%<7//(FHG487(;4.-'H&%=@B5:5>=;19."2$//0)*G5DFA!9(#H8(4,3$EDF*#":+>'F,3+44..B"6:1:1/42..&G8+?;1H+B%$53'#+4A&H''8-%5#35A&G9A-<C+6?%-F@E)1E!*$7)EH*!&7,8EGC.$"H='%(F4<)>*::7#"+-"GEG7>$4$*.H,@<1$;.%!/FA1.6:@AH31=A$;$E//77A89+:=9B;*!"<8-0H!,,+$#>&!+<:#=20C-BG%,5'6H#C1.::F!8.5)%7/':DB4&9#D>-$A*4??<$A6"8,C&BC?6:B#G<,26<++=ACB$8!7.).298BG=9;(/-<0H7@9(*/C
@r7712
CGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCT
+
8D=1%'3#)+1DH?A<>%%,<4)G>@</%94+(")-(6DH-28-'@8*)7G+:4D(+)6*$$-("B8=:3!3%27B(,#D2,EH?HHA'9D06##=87E!$"@'*)F8+?"
@r7713
NGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCNAAGGTTAGTTTTTTCATGACNTCNATCNCCCTAAAAANGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTNAACTCCATATACCGCCAATACCCGTNTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGT
+
$$+%(#*)!"$&+'))!'*($#""!(+&%+#'+#)!+((($)!$*""!#&+'&!+#*)%%()"*!'*&+%'+"')%(!#("%(&+)#*$+))$%+''&'+&!((+#%("'#(''(#$#$&*$%)'*+%'"$%$&*"+%!'')'&$()+*+"*'*&'$#!))*&&(&)$%!&&***&!+*'(*&+)"&&%('**"'+#$*$&*!!!'$")&&($""!%
@r7714
GAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCNCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTT
+
3,B+<8-&0*('G"+%6<<).00E1;>(,9)&=173.;5?'H?,2-'F&.;83*?93C=%D-C'&)"@,.F2E*83>*#98502A*"7F;GE3E2+4$'./'9?#"<>?1)8;8C(.F,CH"+&-BE(6*E,-2A7CF(4.?=1HABE<2-3),)377G0#,,;E35E6$
@r7715
GTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCNGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCANCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACNGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTGACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTATCCGCCCTCAGCGTACCG
+
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
@r7716
NAAATGGCNNTGNCGNNTTTANNNCTTTTNNNANCTACNCCCNGNTGGAANNGNGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCNTCGATATGGGCAACTCTATCTGCACTGCTCATTAATATACTTCTGGGTTCCTTCCAGTTCTTTTTGCATAGTGATCAGCCTCTCTCTGA
+
$&(%#%'&""!&&'$!'%%*(""''$%%!'!$)!'$'#!&("#%#(&))%"$+*"("++(("($"*$+'"$%&)#'%!&#)(*!%)*%!*$''%$("$$#&#!'#(!)"$(&&+*+!(!'(#!"'"&++(''&'!#(!!$%(!"%(")!&$'&#("&#(%#)!)#(*!*&$'!*(%**'
@r7717
GTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCT
+
(90.G6C?'%"DH/@2,.0'*-#9&1?8/D$0(:CE%&+9(C4;-0;<C#H3+$6(DA0@A"$=8#+/B%0;378@>H!;A-$(.A8-3&+45*7<'(,=D&0/E51;.A05.G"..)%C5&4CFF8.*;=#
@r7718
CGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGA
+
4,;%F;@D'<9?&6D->,?36F6.>99@+(%4-?E(20%"5D+99*><1*"D"$-@"<"5$
@r7719
TTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCG
+
3!*39G+,;787E->+41D3:(H9/"F;%4D@:=(A*HCH(2;%'>00AD31;7#-%5!:'<9&3A7*<F
@r7720
TATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAAAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTA
+
G.A6A)3$D(G%/'HF7H#1$/%=45*DG#=7/G%C6>@C!-<(2#&%+EAED.E,9'E+"..<B6!=/+A+A>1F)*)3'=<3&58!8-,</CH$G5@/%942';F!)G6:A#,?)>429(!%+HD?&*%6$%/3*?C5B(:A!F4G<B=+CDB))9=E+,9?
@r7721
NAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTT
+
!-#3!D./7'H%%)$>H>'32::H7E>5C@%@'*D@07*"*A6$E)>9F$0+B--,1,-7.>H663&(9,</,$')&B#?!**E;/>$%E=!E&;:?(1D3*5/#@<7>E4H
@r7722
ACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCG
+
C/A#99E*@9<D1"@HA4%A::A@%E*>@.5*8('3H->B=.7D71,$=>,,5)9+#>*(08%98692$)$/E/6.-."'!??0$9100)BF*<(0(BB'H,*570-"<$.78@C.$".+:;>DH
@r7723
ACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGA
+
320FC;&?1@.-7>;2H")A$4D"+%'BB"D(2$<=?":&4F1@2?6/-H?5
@r7724
GTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTATGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTG
+
>*<6B$2A3(!B?<:<A?G'H1%#-=<-C.G?.72$64#*/0='$=7F1&G)3:@D+65>.(A?%>F+)8'(6B6A7H'!#+(%G?GB"1H$*1%%D.<C0
@r7725
ACTNNCATNNTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTNGCTCTAATTCCGNGCTGNAGACCGCGGTGAAAGAC
+
*%*''())#$+"%#))"*%!(#*+)''#!#+(*&$()$'%%!$*''***'*'%($()()""%"()"()#+)!++!$!+(%&*#*&&*%&"(*'#'++%")&%%*''$#+$!(")*$!
@r7726
CGACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGCTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTC
+
#*/2C%>H!&8C0'>,*>:BC6'8?#3=:HB?B&6#C?,1B%;A;==G2E$G"9376">(=B+,),;A8@(8H@581$*)<EF&((C75'&A<E"C%B5085G61%$!5:@@+68%)EF:'>"5"(D9!.E0G;':2'E8;A<@$"..H>$.23$,)A-F4H;07)'(/D!$>AG."<,@-#,#/7
@r7727
GATTGTCCGGTACAGCCGTGANTGCCGGTGCACATGCGCATACA
+
!F4"/(+09;7:!-0:1-0,)%H:406!B9>-C',';5%D*H!6
@r7728
CCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGNGCTACGCGCAGTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAG
+
B0#'638<=-1=:>+?!;E:$F)7%$=+)=-"B/B@G@*+".5<9!;"+.8>?.3,1=)9B=H(@+>H6.D+/:,?>:#DG8)0H2/5++=*07/H2BE+?-H3C1<+AH
@r7729
NTTNGGCNCGCCGGTNAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGTTGACCGGTTACAACGGCATTATCGCCCGTNTGNAACAGGCTGCCAGCGAGCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTCTGCGTGANATAAAACCGGTATGGGCGCTTGCCAACGGCATGAACTGCAG
+
!(!#$*"*()'**%&"+("#)*"&*"**%$+))!"'&'&*)*))+!"!!**($!")$'!+&&+'(##&)'!"(&++&*#'"#"+#'"!'+'&(!(#)!'!"#!%#&&"&'#!!(*""*')*(!(&%(+%!#*)))&$'&(&%**+'"%+*$(%$$!&"&'$$+*+)!&&!%($+#'"*'"#)%"%'%()+$)"'*&+%+#"''***#&("**"**"'&'!"+&*%$$"*!*#&%%"$
@r7730
TCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGATTTGNTGATACGGCTGAGGTTTTCAACGGCCTGCT
+
"154FH.%/;3,;*/2BC;18=1+E!',4!//-()-,"9(+;99<0E4?1B;E0"9>:&)H5%CF7D697>3G#-A.&44E;?>G?B)&#C+$-%&?*%C56;8:G72&@+71F4"C7/>GH:@4,.E>%4@B-(73G"'(2.7."'/A'7.)=11
@r7731
GTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCGGGACGGCATGACATC
+
H%-=GG>C#@-572%CH1;)!)%<(+4D,'F.E%6<$>*'.CF62(>F?C<5+<"?<(9!-7><-$,F0;(C4:84DB)?3B-'%':1;!B>69AA/".<24F4%1H8>0$A!8<CDA$5=,=G!E7:640BCE47$<C18@*1+)-(50>%;8#102.9+D3%#19';)$454@:%H;'#565B%>A2%?HEA3/+E);3,D.%(2.G=5<1&&;5:<G*D(54D<"),5B(9.?'2892'/#)G8',5"&&B<$#4GC+>,D%//1C'$7F29HDHE48C#(;2.7@)25?B"%*C@7?%.4G+B"!'.$F=
@r7732
CCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAA
+
C?#):>3+G&A6,62&A=;&:2&&)8;3/-$%'69./5HH45FB.2,$.()D8#8
@r7733
ANGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCACAATTAGCCTGACG
+
<F'%A(53'3;,:%2)F,1&E"F!50*:AC-0%F3!C=%B"-(<=-.1?0&.2:DE;B4,<E86F&B9=G,+)(8!AE60=D:E;"('656F3A?/78:@A'98##>%6'56E#)=1/;=H>9(02)&
@r7734
CATNCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGT
+
$%##()+#&("'&+)""&&!()*+&!&"#!!"(#%*'"*#$&+(!%"&#$'&&++))$("+"(
@r7735
ATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGT
+
H5=4D718"<*<C0)9>"2"A>;25/"5&DD)+5&-9<BF*"3'2;;0;.-(*7E("<?*FD=
@r7736
ATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGAGTCATGGAATTACCTTCAACCTCA
+
E>$*E$/?1%7G<D&74E5B82)="FC=9&=4G,*)<AFC,D;C?@&70+>+@#(;?08'$)!1G*18
@r7737
GCGGNGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTT
+
&B+502&A:%2=)"9A/.>'"@A,(CFD"79AC(=(0!?G27,"5EE@D>4:9:)#4$
@r7738
TAAAAACACCTGACCGCTATCCCCGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAG
+
&)#D<DE=#*B43..$H=-)1+GBF2+2/=,<(B4"=&&2GG+7(6)G8GA'2';'5-2"&*D'?9:G#/;A/8?*HE*"909<:B,8G4C#B>6=,47968"28E1D&9!805B2*9C42A@.B1ED-?1-B>GA;+H%<CG*9
@r7739
AAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGNACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGGCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGT
+
81G6#@;A,.6B.;$2.G$?*4<'@,6;-/&23?9;,8(=$7$:<&5>D*B''2"@B/87B.?.'$(D$5<8(;)EF1+<!;C40-5H4B'08>+A6'F67:/7E10,*"<-469>>.:2//@@&#A7(#<(.-83=;C:(CA/()53"<29CH6G,1H.7=#2GD<>4C1&E8)-+4;!ABC..2AG):/%)9@;)0.38C-65B56)4?DBH?$.C741C<;(?0#D%D$4%CE7H29EF?E=@-E:,//E)G1*:EF*+6=/H(7'(E9*@B+#$+)7)B+.!A<9.*F,4)<'34-$6#<A+"7")6+D(#.$&(.1G+?3,2<8
@r7740
AANNNGGNCAAGANNNCGGANCACNAANCGNNCGCAGTNATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCA
+
#)#$#**#"("%(#'!(%%'!(*)!(%"&'%#%))(+($"!&++"$%*%(+#*'!)**'$!&'+*''%")##)#!&)!$#*'&$#'%#''
@r7741
GGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATG
+
8#"#<2*B34-=@>7F*F!%-+2//,*?8%=<5F)73&3*0%:"BE(60B*=AC29:8GE7.=%-AE99:
@r7742
ATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACG
+
4(@1<=09./7&%@1B5A2*7/7+&'!*:,D)(G>&::.1@5"6C5/A>67:,@E<$4($E0%6D%<0931/&(F:D0#A(<F)>6-,349G!G:6,'CA&!<@E%"=86$102A!8$?#-H9,D0G*9/-=!6C5H?G429)2C<7.%
@r7743
ATGGAAGCGTTTATGCGGNAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCNCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTG
+
C6&>3??GG$:H""+D"(!(%@+:@B7$5,F%?#16$C.B&)"+:7!0B"H8%9D*-+3BG'&B@4F)7GCHH"G6;&3+!.*A50):0#:39/H$*=%FE+6&>@99;,)@.DA:,D*928$9=,2,@C1AC&*=/@#C&$C@4D/*4"G'<8=*B!?4//H/EE1;8:B)F*/00+'H3C:*601A7@=4;(@G$!!7$A6D:14/9E"-%G9*.B"<<0C/D@"!2CG75F837>G+H9CCE$/5*++H$>H)$2#)(-9.
@r7744
AGAGAGGCTGATCACTATGCAGANACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGA
+
+(#*!+'$"*$%+&+$!&$$#(*"&%!"%!("+!"(#&+"*(&+#''#&')""$"&*#+&"")#'*#)$**!$+)%#*))!(&*(!%'""+&&"'(!)'$!*&#&)'&&(
@r7745
AANAACTGGAAGGAACCCAGAAGTATATTNATGAGCAGTGCAGATAGA
+
+"(&'#$""!+&&%%"")'"&%!*((&(#*&''&+#""(#$'(!))%*
@r7746
TGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGAACTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCC
+
>H53)1"(-+;*G=">1"F$9HCA!>-7*6@C"!2.,B4G9?18#*4+$':E@CE89:6/!B#$E0+A".B/&FD22C?E@-:"?-
@r7747
GCACCGCTNTTANAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTNCAGCGATCCG
+
%8'H%D$A=>69966,(1.@3C,851=@@'?'$?$'*:?-*56,CH+:?FD'%H@D3E=<<-,8(;@'98/4(&H52%'?2<H0518</-8A")3B0C5G
@r7748
TGTTACGGTTTTACCTCGAGTGGGNTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGA
+
:-=<-F.+(:BD,G2/84))8:5D6@:3./&,5)2,B$5H-+!062?FD>!>B<2!=3E+%8+)76.-?4'H6
@r7749
CTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCANATGAACCTCTGGTTCAACGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCAT
+
39<+06!*8!:E*D5H5?)7,@.H>650A;$C"*1=2E.@A%F3/@C,3#<!=.B5C1/&H;0?$D=D<2+@G8AC(C0-A0<95C<49;;6;"C#*HEF?81:??)-9:6HD4!#(:AE(7&7*#5
@r7750
TAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCNTACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGG
+
-:,$G;8=02/F=F9A7&-B,4&698G12E.E.&H#8$;3$#)D/A78>74*7C.(H>;(6))<53B2*7,H)8&8D(92&D(.29/@:8&!'6F@.378B+/C)
@r7751
TCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACNCCACGTTTTCAGCATGAGAAATTGCCTCCGT
+
F0F89#?&E7;-1'6?%G$7"H,=.G!A6=9.?!F6D=30D6D%?8/1!'%3(>*"HC?;7;:HA-28HADGFEBGD44-/2!F9
@r7752
TACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCNCAGGCNAGAATC
+
:+1D%)H)/E<%HG8G=3?)8G&G"H.9=%H1($0-,=DE47#HA/$/H!:</;'A*GCC?):<AG($H3/
@r7753
CTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCNGGAGTGCGACAGGTTTGA
+
%:7+6.?7"0A+3&8=FA60D>>0;3)C9E9?31&=;3AGA5H&HC1A;/3E9(4'-&*F7%6D1<95890B$;&C$E>$9?#1A'1*8F)3EHFD*7
@r7754
AGGACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGNGGCCGCATGACGTTCTCNGTAAAAACCATTCCAGAC
+
*#!+)#)!*('#''#*('%"##)#!##*#!'&*#"%)&$%++)&("!$+&#"*#+')""%$'")%*%&%$'&#%!*$$'
@r7755
CGTACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCT
+
0AD"@!"E78=7'E/+<4#'4?#%.79/D?=+A.#-"0*/.B7<A-&#1C4+C
@r7756
TATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTG
+
9AH-2%B(C,#(F(7;;+%:(=.-$4!'8C5DA:A"A9!$39,(G6,?$(=B$B!%'(6;E$%!40*DG&E1F.3)=!@GG2)7=3)<8%64C&G>H@:+(B>"G"41&"/%*$8F)6=9>$F@)6'0696BE(C>,7CD9??!:.@>8/7(
@r7757
CNNATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATG
+
$"!)+&$"!)"#%+$(($#%($&#"%!'*%*&%%&$++"!"()#*%%*
@r7758
GATATATTTTAGAGGTGATAAANTTAACTGCTTAACTGTCAATGNAATACAAGTTGTTTGATCT
+
*+;D">34,E$H;)D+>>DAC+5@F55F>!,4.3886-C*2CE+?/+H8CD&%14>)/@,&/9$
@r7759
TTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTT
+
@3D?-.*&"%8H#DG?74G!*D:F<*+*D<1,&D1&$7(@7+'G+:C>-G;*5D8H#GH(9"9B=!)2>0)59
@r7760
TGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTANTCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTACTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGC
+
6<'+61,:/+H9CF<3A<9DH>+52;HF%-+@0608'7C!9B%E?H:?03@'<+-1B:)#BA8!>F'73=&8?7G:"1C74+79"""&A>-!<C?E'!"1E8BE0+D$GHFG#AB"C8*<*>+<;F+4'#*E;1$=;F#A5.>08%5847AH$;D)9>G<"389C9;$E1"EC1(BE.,G4D'AF)>$(
@r7761
TTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATNCTGCCCGGTGTACCGACATAAGCGCCGGTGGCAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGCTGCCTCCTTAAGACAAA
+
")7B*8B>@=,6$1*&6#&C7F%2+(?$)/C)#/G-F62>3G.*,,//#F$,AF*6AC7<7H7=#/*/:5F8$(%51,<9.B+!1:7@$126121=6$&.*02"0)23#A$(;@6/$?&'<5,5-9<8(&1734F
@r7762
CATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATNGA
+
GHF8"@5602'+2:#(%(2!)'A#6?(&'%H9$:@9E4((>HGA2>+A<5@6-B=$A"D6+!;.%C#FD//0,C7:%B'F4G@@=<B@;#%2#;;2;15=(9>FF""E-7:=>,HG<"---20>91=<&@")?G4#=,62ED(5G/-F133GA*=6F<>#=5CF+0;="2@,B0246":6CH+@2*1EBE,4;*1!)!E"&D-6:0H,CCH,09/B62"=(@CG3
@r7763
CGNCGAANCTNTGCGTACCGCCTGCTCTCCCGATGGTTTATGCANTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCNGGATTTCATAAAGTTCCGGCTCGGTGGTTTCGAGGNCATAAAGTCAGCTTACATGGCCCAGGTGCAGCACAGCATGNGGCGGGTGACGCNAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTT
+
))!)$*)!**"++#%"%*)++#!'*"#(&+&"+!(&$+&+)$*(*%%*%($#'$!"+*!&+"#"!!%$+%$#($%"*$&)&+"&*"'*)!'('(#$""!+)&%##)!(*(*)$#*!##&#'++%(+$)+&%+'''$+'*+'$"+'#(&$&"'(&#'$()'(""%)*%)$%+*%'+###(%!(*%)#"#&(&)$'&''''+("&!#+%*#)#"#*&))*!$+"%))*!%($'''+#)'+#)$)$"$++#(&#%&$%#+&*$*!%*%(&'!+(*#++
@r7764
NTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGNTA
+
*H12;9./C.+4A328EGF)H<H$':#2*C1!):/-6958%
@r7765
NACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCANGAGCACCGATAACANCCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGT
+
$83DD8/H(0D&9+'6G;$$4<0>>3-9"5$0*'+:!'+(.'2E(A?#4=1"6.#;FE8>*!,#4+2F'-/()";45!CA2G%<;9B/H%HGGCD4+9#.87E=>8-<4(#16=.EA6,)/=+
@r7766
ANGTNNGGNGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTG
+
#!)%##&)!%+""(+)'%&&)**)!#&&#+*+'"$)'"!'""*+#+)+'%*'"))!+!%"&"#('!%(($)!%*&)$""**(#'#+!$$+()!#&%!(%"#(&()(+(*&)*#'$*'('(##'"+)*+$+)&*(
@r7767
GTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTANTNTGGTGAAGTTTTTCCTTTGTCA
+
:G$(!5@E/79?C&A=('A@:*D-':1H$=$0!!"D.6/.&@2,7.178%8,<A#6$BE%DDB1+:(@
@r7768
GACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATA
+
5+D9$(3:.4,'8&5?.=A!@A5/+A9C)8B,@">&@GC#(6?7+E36%=C6F-%;$CD@,<>:
@r7769
GATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCTTGCCGCAGTTCTTCAACCCCCCGGCGCAGCTTTTCGTTCTCCATTTCAGCATCCCTTTCGNCNTACCATTTTATGACGGCNGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTNCCAGT
+
:<66%2=#;"%58%'1&B6E-*8@)7!="6AHE331@5&(H+)!%98%><)%,B!5GC4(@.(>G7;&C"4?G@1..A&9D2?!;#,06,8=>"#?C?5&0%=/-)C,)0=C"=8$.A>6?+,/$'"?!&9H!"(=-,(7>*=40-$6D:-EBG0*-D;*6."B>80*0.6%H@+1'?2C"C#C-,,;;/B::"$42%:D3
@r7770
NTAATAATTCGTAATCTTTTAGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAANTATGAAGGTAATTTCTTTTGTGCAAGTCTGACT
+
"B-@!!G;E#CGCC?)B6,79)5-E.F-;$4>04$.0DD.@F,7"E>%0D7)(128EF?7B1,860=77$G50F-<,1..7'!+!:.,3?60;?BH%<!$AE.C+&=
@r7771
CACGAGTTAAAACACCTACGTTCTCACCGAATGTCTCAATATCC
+
E#,)2H-/'(!&<0.143<,,,545=0/*B!=*5:??5*-3@%:
@r7772
ATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTANCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCANTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGANTCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAAC
+
?=&!&/D'-7?)49%B$$B6F4!4?EHG0A?)D<&7.!(%&<51<7A=<$2*.A;.#-(#+>B1)',0)1:(4*H@"D&@'A:@9$52(9#>*1,?1!9#DG)4*$FECH;)3-:8?3-?/;;7&;A91>2:!AE7>%EG*1EFD0D<>47=<6:8.#@?<0*>8<F;"%+:)D?-GB?&?"$7219+78&-1HB=<<F?=G7+!G2#5!8EA!A0H(7=/=8;!8B#H2--4
@r7773
AAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAG
+
2@:<=<D%63/#.).EF)-$C!=F@A->#D!8<.A4H!),B-HG!E8')/=.234)GH<<#F+&%7<,E
@r7774
GCATCAGCCGGNAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAA
+
7:?")-3.E-"<*G#H9EB04=G54'6F'.*%/4F09$2F$.;164G'97FG6H01+A-('#!<E9;#-?
@r7775
CTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCNCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCA
+
%+&%&)!'%$!%'*'$&*+('*++##$'(#*(+"%'!!'"''+'&##')#'%&#&$)$&%%!&!&'$'!#**()&)(&**#''*'#+")$*!*)'#%)"'+%*$(%'#+$)+(%!!(&(
@r7776
GAGANCGTCGTTGACGATGGCGTGCATNTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTNCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATNCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCNTGCACTCTTCGATAGTCCAGCNATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTNCTGGTTGCACACNACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCGGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCNTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTT
+
)*)#&&+#%*"'+"+)%'*#$&(#)*)(+#&*&!!'))%(!#&)%%$"%#!$%($)%!+(+!'%(%#*'%&#"""%&)&"%')!%%'%('!)"%)%$+'(&!$"")#*"&&(!#$!""$+(*'*)")$%%#"&+"!"(((+$'*(#%$*$&%$*%""'(!))%"!&+%**("#%%*$!'%+(&&"%$'$"##(*!+**$+()+(%!$&"$($%(+*'*)"('$)!)+"&'+%!+$"*##$)&)&'"(*)")+%#!!$*%"!($'*'%$)('%+&$((#$(%!*(&&##%*()'$+#"#("+&$!!%#%")+)(#("#!)#(&"!"#%+*"$#!#)+$)*"!*('('!#&"+))""#+%(+"%"*!'!"$&#'(($*(&!#!)&%$(+#))&)"*"'$"&+!+'&+$")!$('!++%+&%'$!#'$("&'%(#+&'$*+'*"+$$#*+(#*'%!(*!'*&#'*"$#!*#"%!"&#%#%*%)%')(*!+'$&#&+)!&)+("(+#)&(+!$*)(*"++'#'*'$(#+%*($(#%#'&#%$%++#(&!$))#(#($
@r7777
TAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGG
+
&%0*+5B&(786"/=8E**(C>+-+3=;$&<"/;2=*:B;$.5-8F
@r7778
CTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTANCAAAGGTGATGCGGAGAGATGGGTAACCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGANGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTNGACCCTGAGCAGGCTNTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCANGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTC
+
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
@r7779
NGNNANACNANNNCNTGNNCGANNNCNNTGTTCCGNNANCCNGCNTATNNNNGGNANTTCGTNTCNNCNNNGGNNCTNATNGNGNNCNTGATNGANATNGNNNGGGANTTCCCCCNNACNTATNTA
+
"$"##!"$"!!!$"##!"#$"""""##!$#!$$!""##!#$$#"###$!"!!""!#!!#$#"$"!"""!#!"!!$##"""#$"$$"#!#!"#$#!!!$!#!$#$$$#!!"#"$$$$$$$#"$$"#$
@r7780
CTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGA
+
,(7A'<%8/-@F6*-)CB1=12/)$AA)C.8%?DC*&<6=6A%66%7EF@!4E90,</:;?
@r7781
GTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGG
+
4(%/1E(388G(!B'<7@9+?#?'->5A#>05@+HCH>8<F
@r7782
GGCATTATAAAAAAGCATTNCTTATCAATTTGTTGCAACGAACAGGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCGCTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGNGAANANGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTT
+
,A"@0935"44&H!*595.HA*$"@&#+'15!7!D3?1<&*".B@3-)=,,/&-F-#E*FD<;>><;+:*+#(.%A0-/,:B=%BF.5E5:8+D22A)B%CHE8+*7)>08.10;;:@&&</&3*AC%:,:;E2G'!@)02%*83@#/):0G<#8*B+H%-0H1:1::"&DEHB-29):5)!5;=1H1>/H7F(10A92H-4,A+%32;'C,16H-42<E.1=G":3ED$!%:D-1)6./G$EH2.6EBE;$72'C1#D$B,"?&H(?87'=6:3.9,A;FCCA9B/6;F8*(D8>DF)/+E"8'94@0
@r7783
TTGTGCCAATACCAGTAGAAACANACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGTCTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGA
+
/9,'F;>0C10>!2";164<->G>#-00'FCC$A#;21($>4.338/A?;+@2.5?F@B4A2DF><5%!8?+(",2-A12C$;8'B'1D.;6H4+=B&09EA."6!?3=BBD-B@*F"D3*6043+C:ED793,!/1,+;"<,.6'!!6+2$)C12"5%;3(18C;'89-'2<&H2-?-/5-EDH81/E+<BC%.B/H988E604;.%':G0)8=.'"FG*=.871=8127-@8:B$)+03GB>'7*-=:D38.D#''B((#+?6B>2G-@3;;'#C&"#+%562;4)C"1-E;3;@!)+/E/?!'D<F86((3(*@FG?;GD@C*G.9##EC;(*2>,CA10'?04$?55%#B;"HC60)"H1C!/:"%1,;90:%,2").-G18B)($%6G16@>;-G:3>0EH?426=:3
@r7784
CTTGACATATCCCGNCATAAATTCAGAGGTGGAGCCGCCACG
+
D:0@",-F7#6HA=.&0E#3=$EG=E!"@E*3E5@3*7+&@,
@r7785
CCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTAT
+
,AA-$$-.*7?15H,1@F5DF=0)":*BA2$2)4@E0,C5-:E47;$
@r7786
AGNATGGANGNATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAANTCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACNCCGGTTAACGATGAAACCATGC
+
'&")()$'!*%*+!"*"+%'+'*!'#*+'"')&#")!"(%%**#'#(!#($&*((&&$!$*#($&"+%**""#)#"+"!#'&!"#%"%)")!!*%+$+$('###+('')&&%!()$$$+$*')('*+*!!"(!!*%#$*$&()'("&)"+"*)'+'()"'"*&&!!'%+*#*'#%#$'!)(()"+#$'**+("'#+*(+!$*')"%+#$%#*$##)$*%%%')"&#$(+$+&*"*$%&$(#+"*
@r7787
TCCNATGGGTGACGATGTGATTTCGCCAACATCATTCGACTNTTTATTCGATGAAGCCAGGAGAA
+
(&)+$"**&+)""#)+)()"!!(#&$'%!"&#""($"%""&!!!%'##''#"&*(*++)%*+#"+
@r7788
GCAAATCGTTAACGGCATCAGATGCNGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGACACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGT
+
+),4G?48)E202F<5*F")/+>!55F2!H&'00D!>H0:FE>#28)--!$:%0D<'<*>%6E3;2#G.$BG810)+;"<-,*69EAB%'8>:46)#3@G?&E2-26E%<:?79(06G&!.!."DH==1=(*)9C>;?#1F<C1!
@r7789
AGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCA
+
>D</1;769(&(G2H:*-)2D>/9,<60;.D#,=:4!CC$63AF!D7DC?<;)<?%,#A?7#AB@/7A*?>),**;+
@r7790
TTTCTNTGNCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGANCAGCC
+
)#%#(!&'$+)'()%+$"%)'*&#'#***!+''+)$*&)%)"#!'!"*$%*$#++!"##*!)+%+"$
@r7791
CAGCNGCTGCGCTTCGGTCAGNTCAAAAATATCCGGGTTATTCGGGAAGTGTACGGCNCCGG
+
+!*%*'+($"*+$%*!!)(&'%*)""%%"#($!+%%%*!(&#!"$+$"$"&&"+%("'%(((
@r7792
CGTCGTTGTTAATCACCATCTGGTNATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCG
+
>F'7>H<2FG9DH:,;&@EG8+A,CB8"/0&8+0<GC*1E-HG"1:9C*;'0B8-=0A85$CG-)D7E615D-=:$B/2D&)E..*
@r7793
GTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTA
+
,5*HBG2=7?)(*?ED1$7D7@F1@6A'C%F(,0@BCB99>4<A;(,)@;B,G'>+'1>,,C940<7'(@=@.:%,*
@r7794
CNNNAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGA
+
(&#$&+$"$')#'$'%'"'%"&+#((""#&(!")"!%"""$*#*!("!(%!*())*+$(*$)!&$'((*"!&!"''(!'$")"%&))&
@r7795
NCGCCTAGTTGGTCACTTCGACGTATCGTCTNGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAAT
+
,C>/GE360$FD?<A,$=2%<$6?/"#1*EC9%D0B)4<%@,C#<%=!DF&")$<0;5?G+$C)6<!80
@r7796
GTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGC
+
@:5+*8=*>C4#63#,-'8(;4#0/5,C%!H"75>B9C,5&@0$3)=7%G.
@r7797
CNGCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCNGACCAGACTCTGCAAATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTG
+
)$*,#G9E'F<<"':A9%8>9H5-$=.4=(9!=>A"D#84,A&&8E'-F0(=-0AEA4:=!E166F5<2&=H,635"-3$,9+0!,)$+@-&"=8=='29!9"#68C)?/1@<"6D38":3E,.E)>G3F49?/H81@9@8%A?#1=8@'*+9A<41>G9*G5#A;6:,G:&6E@6,*="4
@r7798
TATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATA
+
C8?>2*'&-G@??)=#=?=0/,9-:&&9G";%35$$5%E9
@r7799
TTANAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGANACCAGCCGTCGCTCAGTTTCTAACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGCTGCGGCGACCAAATCGTTGTAAATCCCCGTATAGGCAGATGCGCGCCATGCCCGG
+
+&$$$%)!#'+&'$&"+(%(+*%!!(***$'$%)!)%(#"&%+"+&!!%"&%!!$$'*$(())#!&)**''#*)&*%!#*)"*)#(%)*#*'(#')+%)!+%#''$&"((+#!&#)"%#"(#!&(#%&%+"$&$""!)+*&)!!(#$'#$!"*!#*(!*%!+")'(+!'$!""($%&++($%!)%)$)"('!#!*&)%%&*!*"%!"+%'*"!+#)%$)$"$&$&'"'"
@r7800
ACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCAC
+
&D<2!**A0DE6<$+E9<?.H:709+H,5-7:A7H):DH17)-/E
@r7801
NCTGATGAAACAAGCATGTCATCGTAATANGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGT
+
)34;%@1CH#?"";)4/.>#%H(6.3%GC174H7,7!A)E=+AB0$0<25.3EH8@3:1-';,?36E;.7@.+#*-14,;":7@#)F"(G1H*$B$%6)/D1<*6=>5,4?$7;-#-?B@E2"&4,;GG"(E4.FC.*+,;E'1)0!4F*<=44!*(47>E:!G.(>?'85=H;5"/B+1!.3;?#
@r7802
ATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGAC
+
E$#E>3/&,C:-2AAF,,D@A&1/;69F3'=@4=5G,B85:G<EDHA$E;<;+4+:';)7%/2530DAG0%#.+<>*&%F36&:"-?+<$H9>=G-2
@r7803
GTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGCAAAGCCAGAACCCACTGGCGACGGATTT
+
>)3/1=+10&G66-,'2H+&3&22&0:@#>/$A+6:)AC&@0=1:BG%5;#E0$8(%C5<%9(D2
@r7804
GGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAANACCAGAAATCA
+
9%(D?='<2--D1A,">$)!C!E510/)'>'95H:7:A19/H(FB1/0F:+#,G?!#23C&E'AGC,2C)6=.A>#(E##-8G1<HD8)>E"D!3=>.7G'B4/)(+14(>DH6',@0/H9)81%,1H485.'ED2!A!3)&*<",@=033@=
@r7805
CTGCTCANACATCAATCTNACCGTTCCNCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCG
+
""+))+$&$"$%(")+"%)!'$"%$+(&)("+%"&!%''()&%)"**!#*$%'"%''%(#*"#()$&&")!!*!"%&+#'(*(+%&&((&"*+
@r7806
ATTTTCTTGCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATNTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAANGTCATATCCTATAATCTGGTTTTTGT
+
22-4!D5H:-#*:8";G>#-+#D(9.;3:A8</A#+/?H,/<3B<;3#D";H<3-3AA;G'%$;-E7$@F7/70HDCG:C4!@-G?+5)$*?38AG9DB4#8$(33(5&D=:,??&0H8;6=G4/$.A2:'6%%D0A<9".*F>B4AD*@C*+'(794#F&74.7@G*?$8<6@4D+:::
@r7807
TTTTCCAATAATTGGGGAAGTCATTCAANTCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACT
+
FAG9D(0"4239F84>"6,"-E-GF2!F%%(=@>5(/H&*68C"8('+8>0;,A1)GAA01D0$0<5(/=58+;+E3B5!/D;.@?,3=9".&#?9E:1'!;H)6>>D)1DF!B$;74-"2C37$G!;30(>+24HD08>D&>8>C.G
@r7808
ATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCANCNTCTGAAAGCGGATCCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATTGCGTCCTCANATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAA
+
DG:@?'.(3$!!C")2G7&52,1A2)!D17=F/#8A!E/0:76./$$C#:<C%+:(&"1C1?#24-2D37?71(6310@D5>A,:3+6*B856C)E7!4'(.+16#D?>29)&(%G"@2A1G"*@;3@B8B,)9/A63H"'3<=$>"*!C?G/-$E7'>1H71C67<3<C5=44&<B<H5+/CB$,!1;(,F1':'59"5<</$!2A.+2,H.>49'?>G'-?,D57@>236GH<@/H191-D)%7%0H#::;7.#=<32G:!(49/2H.'G!BF,@
@r7809
GTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCA
+
H=/4/>618:HE=G=!"A<:/2,3>'(4+?>F+<)A)8"H#<9('<60$590;!:G?E33E21@7E#:>H126?DA">'30%#@=1@+!";17D117&C=-HB
@r7810
TCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCAT
+
.EA2C$0&1.'*1&=6/.+B",+@$HB@<&:E+:!@A6@&05("6/(5415E*)1!CD=0G"##54-%"7-
@r7811
CGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACC
+
2G,!%C+H?'-;90H6;/.!1%9%/<+7"::*G)H&+46:6F*%.4(%E4
@r7812
AATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGNTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCAT
+
B8.H$*2A/(%F.7F7')31@D$+>-35*3B69D0F="!"#/E'F9+3,D:=FA"<<00/EF?FDH+"5+.8'.F)EE=);99+%=#=8=22:4C8:5C+2EE61C+8(F5CB4'F?65/BEHAE@)?E1(7@.%H5F@$$9A!8<4%14C6-(6+(EF4(8&'@$G')=2B@@.50&,=3FG7B7D3<D!/5B>FEE7>E
@r7813
CCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATA
+
4.?F&AH#EA;:AH8==*B>@$$)!=96F#'=@#7%4>#+C!;3D57.D91$08BC)%(:))C?2%+#:)D<+6;%#!
@r7814
NCATTGTTTCTCTGTGGAGNAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGNNCCGTGATGTCAGCCTGACGG
+
!E-$G!*6-E*-'(F4,:/F,7*18.H3"*8/6C#/,CEH8*@*H%8,8G"7#E0E"6.5<F5@%++,+#55<*DD6BD?A&CD6=:G(=H?03/':0
@r7815
ATTATTGNAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAANCATCAAAAAATACATC
+
F1%'(@6,/#!,$E+*D9+6/A:'6==++A:C1'-,<''/*2;FA+<E2!)>?')H"@0.E(,"3>@*$2C#8"3E<503F56;B0(?!
@r7816
CCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAAGGAATCGATTTTCCCTTAANTTTCTGGCGTCCA
+
).(F0!DB?4H,09G+=."E@@4EG5!*HG9(1,$&F;-F!175GC-H7/)()23>5>""&+E4E!89/<*5"5E,,</!)%</FBE#4+):/67.GHD2*1@8#FH:1HG=*33B2?6/:.'8'A5=E=
@r7817
ATCTGACCGAAGNGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGANGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCANTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGNAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGG
+
G4*;:E:!<:752:>>B%>/H2%.')(B/,:9H,22=EHG6C>(602H:99>3?4F2?&0$6G63<B#6%9$D<'.$4'2=G/>E'.,14//A9-D0&45F.FG">B)2):,2&?2H1."(7@-F.$>E8;F@42%?4;&/3+*/E5:H#9+8A5;"&,2A),<)DAGD@>10%48/07(E7'?=A-/"::)%,*922<!2%-$G0C&H%'B2AF;=G%42=6B6G,+%;*;3*?($HF$G%B-21%HC7492-*;H01)&3&G-HGC>8#""1+=95G4$7$1G!"D#0%.!C:,>$9EG<DBHC&&2&%3A.(?9+:"4:",H1GA-'-+3'<5@!6?4+,?#4#+6),901/E'9:A<!0G#!<*$5="H)/C!';("90$C<DAEG1F,<0H==C%!:-04E$#!<C@5D@"&$7=!#B*@*30%GE"?G;F+8!C3B*(=05>%
@r7818
ATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCCACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATNATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAANCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGNATACCGAGGCTGCAGTGNACAGCGGTCAGGAGNCCATTGATGCCGGACTGGCTGATGAACTTGTTAACANCACCGATGCGATCACCG
+
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
@r7819
TGCTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCANAGTGATCAGCCTCNCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTATCCACGC
+
-,#+?#4'*49%'$A'!A"!9'A3*1B8'>=@&=>?.-7?16"&*)*%A>610D),@2$1;##,!"@('=@%".-)0>,'G'1?:,8/(+>,&2:>A'.F'8*>54F6@E&B,;G04;@E&$=)
@r7820
NCNATCTGGAGAGNACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGNGCTGGTGTAGCCATCATCTTCTTC
+
$%#')+#$'&+(''$(%!*##)$%#()'&"%%%#&)'!%&'*(()+*"!)+*%$%%*)&$&#'%$"$'&)%($%#$%!#+$*#)++*%$("!((%"&&&$)"%!)(
@r7821
CCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGC
+
FG?=)0"A9;:#EG->:%-C"(#4.>+59*!:@A39,A/@DAE2
@r7822
CCGCNCNNGGCGACAAGGTTANGTATCAGGAGCNCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACNGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTG
+
%"%()(!%+*%**&#)"#$%'$('*'')$$!'+!#$"!*"#*###'*&'&')"**"#!+#$+%%)'""#+'**&'%*"$("'(!$"$)""$*+"#"&&'"&$!#((&'"*'!"&'*+)#&#*
@r7823
ATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACGAATACCT
+
9&"EC64<:.F.0F(:042;)E"#%E':34$13.FD>3EBE(&-'04B$.C8,/H<+B'3,,/5,4.EGDC#&CEC'$4**>C1,4:;<A/<#8?8(>?!:8%#B$8"
@r7824
CAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCATGTGGAGTTCAGCCGATCTGACTTATGT
+
%26H#/0F3!(#6D!414$02#)877%*E/C.!75:F9A.,*&!8B$'!B:4;C4'8GE,2G9?3$=6<.!D6D3E/G
@r7825
CTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTA
+
C,'C,.4@.6+&$6".=9*%49&G"A0@'DC-E:';'F@32D*E7((G;+6B/(59&7:%
@r7826
NNNNCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTT
+
)$#!+&('&)'+&+))+()*'!'+++%#(!)&!#)(''(%
@r7827
TCAGTTTCAGTATAAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTACATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCAT
+
/5BB30C$E3H=725,&)+9@(E1=/*6#1-<;/8*G77C'!+93%*?73=5B%H/D9EB)9E5D+9(DF<>-H/C&!3@-6BDB(A@+H<(+3&=;9?G,54F*G
@r7828
CNCCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCACTGAAGGCGGTGNATGACATGG
+
#!+*(!$!$%#%%"+()(!+!)"&#'"(&"%(#)!+!!&&)*)"'##$#*'&!""!)!%)#$&('#)#+(!**#!("%)')&*"&#+'(+$**!!"*"&)!'!*'$'+)%%'""+%&)'!%*"#%%$*#$%+!""(+%"#$+$('"$$"(#"
@r7829
GGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTA
+
"F&37B4D0C*H@F&%>A<A?B)+H3"@653,5"%=%D55,*-,/1H&(+9&);48@E#%0%?;C58??=3DF4C>"*60H48EC%10.0E&73-$/487)A'@2%900>0;D-04-5+2*1>B</,B71:9:@E500)%23B-?E4/C;79D3+/B7
@r7830
CGATATAGGGATGAATCGCNTGGTGTACCTCATCTACTGCGAAAGCTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAATTTAATAGGCATCA
+
'<@/8#-G>9/*,F6":;)!D2+"4<84A>8E@,&AE=5B*4#9'7'G+(;40?#.2+E=%975EH4*&-1)A@C%H+%"D'#F:+8C#,E%&5,63;0B#=<:G
@r7831
TTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTG
+
,B..E=G<A:1C;>!>=?F@>"H>2F*">'>6GD"8&6:?28/G<
@r7832
ATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGNGGCAAAGGAACAAGGCATCGGGGNAATCCTTGCGTTTGCAATGGCGTACGTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGNCTCGATTGGTTCGCTTATCAAACGCTTCGCTACTAAAAAAGCCGGAGTAAAAGA
+
+<?<;C=#:@986A8.;69E343(B*4$(#3>64'*<*"02%C4$."8:'G17C9;=68"A*;0>5/D'3-7"$0'789*H'#4=*,0.6%8+=')F':.''EA#FC"5D)A;)!GA1:/C;08!!+6<;1/66)622C567:8!E#@>!B&D)2C2/72A6!B2-4)C;?B,D,D!!@,F@H>G3;+E"7<F)98;$#?2?262<!<*+-=76.!&;64=%"2*=7+&-D>(&F4$7B6/2=<;><5D$;7D1'*D8+$//5*=9'0A4!@=C-"<<B>3$E-H<6D9CE.D182"(8A4"=)$&17/?+F0EG,;2@;"$*H</5D,=
@r7833
GCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGCTTGGCGGCAGCGTGCTT
+
*H#3*F0#?C>=C3*D*DA3)+.F8B<'&=7*2:$*D3.5E%,89=$BC-$4A&56$(D5.;!8E:)+4@C'+>*,1
@r7834
TCCCTCGTNTTAGGGGATTTTCCCTCGTNTAGAGGGTTGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGNCTTGCT
+
;@E5F"3(8"FE2,-"*$9(/%<9)639G(A0GC)$))?883""9A<<G"71,B((4?71<<*DE(8?H@;B'B>+8-,F47-3E
@r7835
GAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTATTCATGGTGGTAGCAAAATCTGGATCACTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTC
+
,'2:>C>/7>A56(+=074A'0?F+$:.8+<6&1;C39D?>%;?@/+/!)%4%*..B-6-"9?E5>+GA=7=?4B!1?C.1GDG,%.B5+=CA3(G=%,6@(54+83"G04D'2B6&6E1EG>6%>-"-='
@r7836
AGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCNTCC
+
@7%BHDG*8>>$=+/7'>41=).,>CD4316*/9$#AF%%)?5&1"8=:F)!*#F$F)89">G/&6+6;*7+>-&.C@1H,F=!)90=8/>820023?DC<5=52HFGD>&/C6=8;/88+&1&"<-FF.A&57:DC)/3=*(
@r7837
TGAACAGACAGAGGACGCCGGGCCCGCAGAGTCTGTTTCTGCGGGAAAGTGTTCGACGGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTG
+
H&8%/;,<=53GH'#0(:$AA-&2,0%)D";11AFE2/4:9@$6%+E':H#*A+<6$"&0A4!7@+D>=F?3GG<>C9;0$%$D@0);%;;+BCA-8."ABC49>F&(5;
@r7838
ACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGC
+
3-==3#'G$*A)38HE71>+D>"'+@4B6-+!0D5$6C(8=+'9(45,1
@r7839
TCAGCCNANGAACTAATAAGNACGAACGCTATCGACTTTCGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGNACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGG
+
&*!*#'%(%'($&'"")")#"*($"+)"&"$(')(+'$%%!&"*)#'"(*%%'*!"'('%*$&**#"!%!+$$$)%"'$!"%$&*")"&)*%'($$"("&%$$!'")(#(+$&(++$$'#$$)*$'*'!(+!)"'"#)&*#!**''%!+&$$**$*'++'+)*!
@r7840
CATGTCAACGAAGAACAGAACCCGCAGAACAACTACCCGCAACATCCGCTTTCCTNACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCANCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCTGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGNACATCCCGCGTNCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAAGGNATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGNCAGACTGCGTGTTGGC
+
,-5EF90,3>F#5"1AC;/57)/+::GBC(:>&&B3?43B9/:;>DH>H4G32-F.FE@'C%:?/;%#C+.<%F%>7H?/.(-H5F-#8?#ABA#6++6,-3,()F,&@%39=<95E6/5D?=0-,05=)&:24?9!$A8+6!9."A$0@-B*G332*&HCA+(='B$';35AAH-D'9&2C'%1!8-2=!4',H=0;CB(5@98+#$&B4"4+H,B+"'D.D*(=,;%6-;5<4'G)()6)F@)?G&>D9E4EC"=*!<0;4=+BE&C!1"4*;.!F7$(C6=C=3A9!A"E4E/2#,,==9-6=G,7B2),>#<
@r7841
ACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTNGTTTCCTTTCTTTTCA
+
=7*3(3A(/*5":/"?**-9=!A>92A?;(5B<";&>/4)G&A921<+"#?:*(96?=/+-/:+.*@>1(72"B+?';8$2#"-E7B'E6DBE(@
@r7842
TTATTTGNTTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGCTACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTAT
+
A7<<9?8:>,#$895#*E(8!&?D2%4DD%0&>,2,"9,/*--41-(H%;<2)#5(1F!<0A"(A6)A?>,<4$A<')F)!1%+C.0"3*(',()*+GC95
@r7843
TNGNACNCCTCNNTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACCGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAA
+
'"$)!""#*%$$%)'$++$)!(*&*%)*#&(""#)(&&!&*)(!*$((&+$%&$+)!$$!$'!+&&(*+#'$)+%&)+(*)*)+('(+$!&!)!'$(*('*
@r7844
CACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTG
+
/;(G%'GF)8>5?1%=GBH"C+#7&$.#!-C<73*EC91)E%(?F*!@"1&"B9H
@r7845
GGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCG
+
'G9A#0HB%(+'F7:1<:79:""#@.!<"$HBE%>8/7--H'-9*,#F16,+-$+!?(:F&1'!<.:21D'&F&/3"43C*9.0?)')H1CF):<1>/1@C2?;H$0F-=E!+",B37G6-(C(&4#A=:8?C/B5&>(9
@r7846
AGATCGGTTTTCTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTNTCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAAC
+
CFG39>>7;(?FB:,-@$#B0@8AHA0.6)EB<4D'"E";7<@'AE3'%D%G7$.!;,A3)/&,8?-*9!@43$>,1&75C&=59&HF8G8@)!(G.A("D199)C#5#E+%@")E!*@+GF38-B(7#H?4**;8*3#2$150:+:;5,*80%!B@'!GA,H0
@r7847
GTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATTAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGATATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGC
+
93,1&3>#9@*2>0:D15C22/>=4*E:H?/<66*A5:G!;<"2H!>GD8=$"#)>6*2B+*.8CBH6814E34?5<H1C3)G2A!G*@G$E,%A0"?7:,(5(!G1!<79=HBD8:-?H.>4;20H:9G;1D").%)7/%=-3-GH'1)$G@D5#E,#%2@#C
@r7848
GGAGATTAATTTCATAAAGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATTTTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGA
+
>+/>,6C>5+%F$82&#&E;98=4+0,%&HA%H4G+>36C'B6/&8'F8<G')%;3*:CCD*%7<-3=7!#2:,?;@E0.:0:6E:;!3!#$D;7()B5@$E5&&;8*7'4%""8=.!*>02*6?=53/%"-6A7E>AHGC5A'GB;G('#8<"7,E%?$-
@r7849
CCGCCATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGNGGCTGAGAACTGCTGGAAACGAAGACCGTGGATTTCAGCGTCGGCGCAGAAGG
+
0G&0%.)+=9E<B%5GC7F4<+"8%CFH%-:HC;0)4$)D(%F),C20">@51C5!24+5"3H/69=;5>66'4C3D#?-DG<):&,#???@4065F#E;()"$1?@%D631/?0:1+A4:C.G-)-1&*&360'=+<7&!>)+FD5'+*+D&"27@75"5B/+<;'+.H*1*5(>*C=B@@.2>??B.C=?>+6G=E!:-G//&)*8G/,2=B!B-D$6
@r7850
AGTCCACGCAGTTGCTGAGTGTGATNGATGCCATCAGCGAAGGGCCGATTGAAG
+
+%&")#(&*(!'!%#!'#"""#)$!&"%#"+("'!"$!&#&*("!%%)"#%$%"
@r7851
ATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAG
+
D-G1C/3;G@<*6)CHB/.G6/'*#/9.>%/@H0!7>;%@;B7*'6.-*>%&FC:8<%(80;'*<(4?E+2EE5,$/-727#5HH
@r7852
AATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGT
+
,G=1:8((*/:@&F::,F=";G,+1$;EH<3</"#46:'C9.<$:)%
@r7853
TTTATTGGAGTAGATGCTTGCTNTTCTGAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTG
+
)?035G&B%-"9+D-):G+29>*&&#&(,6)%"<.F.#@D@F%C:>C@7E;)0E!*&>)1=9!BD8E9#=+CA6&=
@r7854
TCCCGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAG
+
-H,#E!%,)F0,%+D/:G?<$)G=:)H*:54**?>D0=0(**;9=(7!&H1*5;)7A>'EEH-#0:$F5C7//
@r7855
TTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATCTAGTGCGCTTTCTACTCNTGATTTCGGTTTGCGATTCAGCG
+
6&H6"D)%)$5G7037(%/4;BF1)GC8,A'F43*4((F.:F'7E:=/"5A4.4B097,2(?15</1&/:/6=='<F.5%$'H&#/-G"
@r7856
TGTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGC
+
*!86%.5B-57)&4.H>>9"<5#G;EE=8-@-2F=7ECC+/
@r7857
CCGTNCGTGAACGCGCAGATCACCGCAGCGGTTGCAGCAGAAAACAGCCGCATTATGGGGATCCTCANCAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACNCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTG
+
'*'"%2$0D2<56*%>B4>'H'9"!5;0(G=F<,.<&+0D"4D&629/@4?*("FH58@4-=G(-E;;$3495'B9A'8.01>B,61E/F,(/1586D#,E'5D?*B+B=DD'A@==6D0$+%&G"B7>.?7:H@((#@H1F2G5@1%6#9!A>@/8"D1$/#5F&B+2#+H7;3)0!&F<?C*>8=C!H4>+%C=GB>.HEB$>4)(*+
@r7858
NCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCCCCTCATCA
+
!0),2:8!%)--*?'B9?=8@2$>8H.6'#=#/%G:9,&&-0#+C0&2'"1EE@>1*56"D89E('&/=@>'%-5B=H2;6/-7>>*B;C(&52B#:&()6"=GC04
@r7859
GACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCCGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGNGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTCACTGGTCGCGTCTGGCAAAAGTTAAAGA
+
;8H/D?-35>B';7E3"A<:B'6-4"+<DG=."2G36EB%G?#+>5?7D-;/"1B@'5'%88::D@(6*4+-34ABB;+%6.D5CH#-!B":97D%)A/(;!>(4*1D%5B-&G=+#1+F@6@2=F=&)>%:/3,=@(6>7C<(8=B<*@!&?%?3=,0#9C-;F
@r7860
TGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACNTGATGCTTTTCGTGCGNGC
+
?-=?B!6*97F*=9@3/D/",%5-*6HH#*<>/93%#$"%-B=1540=!H8,H'%>.1=A0%27@823F/C7(/;1=9,"*%D1B$9=C;)#+9B/B@FC.4!G$CA=+*H8@.)'C,B?C7,2B67-'
@r7861
TNGCGTGNGCCGTTTNNNAGCTCNTTTNTGNCNNNTNCNNGGATAGCTGCTCATACGAGACACCCAGCCCGGCANCGA
+
#$*)!$%&&**%)"&)$!)%"*%'"!%"!)#*#&!*$%'#&&)#+$')!"#")"$!!"&)*"!)#%""*!++"&*+&*
@r7862
TGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGNGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTG
+
=..!"BFH67,:*A!?@A$/:3!G"!'/D+/<-C36E&AB%=A8B2D0>#!71:/&$&/:%F+4/3;H-76;"?D;:B4B05/C"E.&4'&1*>.@4<#BH<:?(H%GD'G.C>
@r7863
CTACAGTCAGAATTTATTGAAGCAAATCTGAAAACTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGA
+
+G70B/,F&5/+.#-'5A96FE"(-!+#$&-8>)HFH"1G#1=:<?%03G98&@<G;4=157:03+$E)???%+<B/2$&-&")D%6FH/@!&#B78D)B583*
@r7864
TATCGCNTCATNCNNGNNGCNGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTAC
+
*)#&#'$&&"&"%!#'#)'*$+)$#()%*(%%*!$+&&$'*(%!(+)#')&+%$(%*$(+
@r7865
GATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATGTC
+
A9(*A-/@8CHF8A+8,)'A;E6(@+*(<C*&1C38D2):FH-$E:BG?*E"H$.:/)64-$-!-%2>.//=4'@&
@r7866
TCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCTCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTAT
+
!')*+!&($**$(+$)$''%*('*&)'$&'+#"*#"+')%()$&*%*%*##%!("%)#)*('#"+%($$(*&))('%!%$&$+'"#&$*(!"+#&#!#$+))"*%"&+$#%$+*"(*!$'$*()+&%+)($!#+(!!"%%%$#**""%%$#"#%'#*&')!)&!+"&!(!#$*+)$'(&$'"!')"!"$)+'*
@r7867
NAGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTG
+
!!'+"'&"%*(+"++(#$#)*""'&(&'$'+'&**(+%&+!'*))*+%)*)*(%$"%$#'*%!)**'&"%+()##'")$&*'+("*"'"*()&""!+#'%"%)'%&+')"+)"'$!$""*%(&#%$&"(()$#%&$*$)')%'*!"$
@r7868
GCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGNGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTG
+
"9F?<8=#+@%>#:-?&/1AB0D%-#,,#C'E'&?:H2@B1#=<&#H@H<!D&C,#D(D/2FF@-A;:G;%@B97/93-+#D859(DF7H*D-H*/<!6@A)A4%>9A3/B19@?@272$A&0,8A;5!%%F1@0C;:B0A84:?5-8C/;!$.,*5@>;C!G!)=%<B&G.,;9%81%3C8'<+-!@E4:*A:
@r7869
GCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGG
+
)CE53((=*B7/<G)=7&D1E+H3D1'*3G%D5&@F>0%8:4B,-#86F06G003+?'??!>%$B
@r7870
GGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTT
+
'<005*<HC)H'@(75=3$F>A+H+H23F*$8?9:ED=00A;#E8C;<B3B5<&5A;?"#*E*!(5D?131&/?C034B,:/4>*F+'$2EBD8F.<",/G13)C,".*8D<@*(C6C7#*(
@r7871
TACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGNCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGNTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGC
+
$5G;+/@8F;';:!5@4#3-=0H#'7'?C+!8#;F0F$.;&@-?3&?+%6?0%7+$*0C>@(D5(6.1E=G$/8#&3>/-C@#5@&$/H!F5-(2:?:/A*0!;0%;0G1??G.2G%:/@G1+=/3@+A%G)(1&2(?21;)!=%4DG@H%6990H+?<5>*42&;=8G:+B?">F6#$)6A!96!(/H0$FFG"/461$!80?G+6'1(C<@2%216C5B;*:$?A+"73@/+!!14!"D')'8D
@r7872
AGCGCCAGCAGCNACGGAATATCNCGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGC
+
13,G.@8AH/)4&976,20$>;%G5,?8=!0EEE3--8;!C:4F:7'*)-0&/G3)G4"&<E((>@6$,+=1F9;9;-2*,6("BG5<<+<3:H$2FH.54<!GG8<::!C
@r7873
AGTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCNACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGA
+
*#'GAB,.H=:-!>@;-2;"80H6H-C3>,<;-(;,;#-B?G;83A,88'9:6(?,0)8%,$><*@#2A5)(&.',2G0(116,6@2B!+":1/EE$4#AF/:'6G>((C&!22.D,64*'&=%B.?%5)C!37#6.2F+?")1;<4B>#B9@;?H:>EB*83!=E?3-4"3
@r7874
CTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGGGCACGTTGGCCTTACATACATCTGTCGGTTGTATTT
+
%&+($!"$'%*&$+"*(+'")!#%&(&)#)+!%'#%+$(!&+"**+&!"##+(+("!%'+)'')*!&"$+++&#)"!("&'"+#*#!#%!#&+#
@r7875
TTGCACGTATTGCCGCCGCTTCTGCCGTACTTTTGCTCTGCGATGCTGATACCGCACTTCC
+
-@&G9DC&!?G7:H$.#;>6C">$B#AA@0H@5?&60"3+0+"1,8A1C")+%C9$;/22&
@r7876
TCTGTGACNGAGCCAACACGCAGTCTGTNACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAACGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGAT
+
;=A((00-4:+:"$;69-2F3!/"7$AG(D/C0!)-24?8+$<5"3C?9EF:F,.=&9.>0?05A;8$.#.@/=,B?+'&B4./1)1;+=B'2D%-)B"@/44==D'-2$,&$0H$B4.3433F%?:&#>*>4/?(,7BG7C,0E@;)<+#<5"=%
@r7877
GACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGGGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCC
+
81.>253'=/E1,A?'D??$H%:0D5.(7(8G5H:":5(A<#(+5HB0CD(=BB;3==/8F@),:/CB<9.&/;.C(.5'7')>AB/-%C4"GG#9E5)/EE;<C=$E
@r7878
ACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCNGCNACAGTCAGAATTTATTGAAGCAAA
+
$8?<9%!A#(A*,3C45764>#/D*8A$EGF(!:4'$*$.,A+.%-35!=,)A6$8>'%%1F8D%$-H$.-A?.4&D-0@:#25'!,HE/0E&$.03>B!?4#8E@=??CC:&1A(;.)'49)>%543A06G3
@r7879
GCCGCCTTTACAANGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCAT
+
;<#D!>930#?GHB"@:%/,'*<GGF*,C/:0).F8A-$/>3=5979,517<+=-?-<#8@CC2C,6-$,8;,;B?.;#F-6.56&,E3)-1DC"!HD:01,;
@r7880
GTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAAT
+
;8:E34E%,<D"7.-HG1'4+D?+F5*GF@:593)HG6'"CC+6<$4<#,&=24@)<""'$<2
@r7881
GATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATAT
+
4D8-3$,/(!C4!4=&"91@)D&9D#B0200H69&#(-*>$:;+(+,?4;DD7'
@r7882
TTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGATGAGGATGGTGCAGCAACCAACAAGAAAACACTGGCAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACTTGATGACAGGTAAACGNGTGGCAACAGTACAGAAAGACGGAC
+
>;.$-#!"0!H.)"D93797ED)E10H?;B2#<-%CFD1A@#6>*6A$?*#=-A/D1D$C'2-?@@3$&?";%=>:/@+9=+<..4DF$("9*$E,#');%:-!0%4F696B.%(,@30"27H=?A;'4AB7&B47(+A?&,8%6,-EG6$/5984>)&*D<*'D1D(>7>G/@0(@!F'FA/&73:61*H.6:;,/&!9?H0<;F4E
@r7883
CCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCNGCCTGCACANTTCACCGACGTGGCNACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGG
+
F*H9@:*%3/>-$D*"80@*?/3<E2+C+<**H$+B*;02:E-4=-(-#<,2?D";;B>8"A0(5&8!>AB%5;9,5F;+@<'G!)76,;4HC.CEG)C::!2=><BG>)B#621DH$+F0+1E2)B6"13#A.2:H"41:03!D@#='7G/36%+#CD$!H?"$,G0:&A)09D78"A%9-;7#C3C2'?!AE$E7(%'A
@r7884
GGACAAGACGATGGTGCTGGGGAACACTCAGGCNCGCGGTCTGCGCACCTATGGCTGCATTCAGNA
+
#675#D9A%B'AB!5*!0521G2*+E#=6-'.A3D":$0';-&.)!><?*#)'C%$CA3>):):/*
@r7885
TGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGTAGCAAGCGTTTCAGACGTGCTGTTGGTTGGACTGCTGAGCTGCACTATCC
+
>@23*:8%@4*7#C,D<&?<>2%0G7#%;.20/'"01*BGGH&5#B+'3=@$-EB"5C@?;5<EH9>,+;-&BF"BHB?3?9!%-3=/9A&C9
@r7886
GNTNCNTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCAC
+
'#)!#+!)#$"'&+#&&$&&"+)$*$"!)$$#("+#$('"$*'&!*'($%%!
@r7887
GCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATNTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATA
+
/7/1,&5""$<B?B0#1#H'$),.=(</&F>1$E*&,,6"@3:,6'5BE%#C<BCF47AGB)7$7G<@7D*;:3,5-&E>>3(F4A98=D=:4H8-!.2(&.$?'06&<?<,8D69&9#C954A6/%G4E.'(781/#/44&9$.?;:='-&/77:HBF62F*#=0*G='D#E33';<<.7!4A'A9%3H7!<!>%(%>B/-:?8".0,:A6>H=$?9
@r7888
CTGGGATACNGGCGGGATTGACCCCACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCANTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTA
+
+9";5""A76&4!FC2:#=-+=5H2=/5F)8+3'&:3)6.-!G(+%>*?4H(<8))?<7(-%8#ED=H5=>G%92+*+#9;?H;+&&GF=;7B&:F007000="4(3E*AH'84?,/8)30%<'=(E04"<6D5@8'%G':).&5.>;79$C!F/2F50!()7>
@r7889
TGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGN
+
(G?:A&=$#D"C3%GD'!?86>:,2!4C6/>0=19?A0F@E3="6;/$<=@-
@r7890
ATTATGGCGGTCCTTCAGGGCGCTGAAGCTGTAGCGGAACGCCGCGCCATCATCCGGCATCACCACATTACTGCGCTTATAGG
+
&&+"&(&%#*&!"+(#(#'"*""!&'%($&(!(")%#**#!%+%'#+!+"&(*!%'$#+&*'%$'*'!+%++!#))')+&+&!
@r7891
GGGCTAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGT
+
@%(+'#A?-/)$1)3A;B/D@86$AC0@$H<7)*E569+6H&A97><9420.!G=.G#*135>A4!9'
@r7892
TTGTANTGTTGGNNNTNNNNANNTTAGCNTNTTGATNCTTNANCNCNCNTTNTNACTCNTTANGNNANCATGNNNNANNNTTCTGTCNGATGGCAAGCCNCNATGACNCCNNNNNGCNNATNGANGNCNCGTNTTTGAGCNGNN
+
$##$!!$$#"!#!"#!!#$!"$#!$!"!!""#$!$$!#$#"$#"!$$#""!"$#"!#!"!!"#$""#!##$!$"!!#"$!##!#$#!##$!!$$$!$$"!#"$#!"$"$"!!#!"$!"!#$$!!""!!##!!"#"##!#$!!!"
@r7893
GACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCAC
+
H5:D"B!C=++,E%D?30)<9$&@3?!2".<5/3)97:<7/2!,$EGD329%'=4$;4EF?
@r7894
GCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTNCGGCTGCACGG
+
8?&C*0#E:85,#18%8)@45$@(2+G#D@""4D7AF(-2<;./1F:7$?;30B=:3,E.:F,H(H+-!4=:(A;'#-$8"""F&,F8?*GF$&B?)+.5,-FD1!+F=?/A.<(D71!1()(-%3,1</?=@5<*C*49.E!/3##=*A-&EC&25;=;3+9G-;-)#;#5;?7;30=%,/CB?$:4.+C/0=6'/*$C5:"C%2/)DCF<?;(%.#-E;=E,71D>!3A#G2CBD:E&.FG7#HBA(.!GC
@r7895
GAAACATTTCTTCAGGCTTAACCATGCNTTCCGATTGCAGCTTNCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTANTCATACGGATAGTCCTGGTATTGTTCCATCAC
+
6?3-(GDD)+D(5B,1%?@E1%-+',+&5$$E%;<A=+=DA<9EF()*!<C7D>3.DGA*$96#E969G%+/D:#G546E'2#&&@E%9518$@.;:)&=>!$)!B(;,:7!08AHB=.%D=24=;+;<(B
@r7896
NCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCNTACCAGATCGTCTGCGCGGGCATTGCC
+
%)H/-;3<*;C5)'+"@/4H.$+.F%0';:F:(2-)!F*32"F:3,#6-0.49CE0#:&#F&7F*)(''D,
@r7897
TTAGGTANAGNGNANAGNGTCGATGTTTGCAGACGTAATGGTGCGGGTGATNGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGG
+
'#*(*$#)'%!)$&")!$'$+#%!$*'+"(+$%&!+'"")"%%(#%'$%%(+*(&#*%+%!*#'%&$%*%%!+#)$(*#%'*%')"&%*%*(!!(*'#
@r7898
CGGTGAGACGTCGGAGGCGAAAANTGGCGAACGTCCGGATGCTGAAGTGAT
+
$FG?,0G$*-'('0&!;4C&%%(9D@DD:+.@E56*-2:5:,:'*<(HDA2
@r7899
AGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGC
+
),)01"5-G57"&C$-H(EE)$9=,A3F06H+"'!%/E7=@77=1(6
@r7900
ACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGNGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCNTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCAT
+
656(06*%4)B<3:C1$=,#CE,-(6>A12#(%<9.5$.H+*!9B&;!G?((+%-$;>,0?6/%D&"5F+B17<':/F<#$D3&2/EB@9)(A-F,B*D(/2.54-51,<84G>76!-7=.E/&-D7'$A"+:'5F?<8"54'64%H8,=4;)BD".!>&.&E8H=$F:4E.(';'=%:!9.B:&B/*H1=G?=:.D$H?@;B3-'&"D3@5=
@r7901
TTAGTAACTATCGACNTCATTACGCATCGCTATTACGGGGTTGGAGGTCAGTGGGTTCAGGATGCAGGTGAGTATGTNCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTTTAAAAGATAACGCTTGTGAAAATGCTG
+
;A!"BG77<D.;>0;#50@#A)%'!AA"34&$3?8%!E)*A1.7=8EC.0:AB#;+D#/146>575),%&+4?FHA73G7=5B,-(>91<G':'((#&DCH:5%=1DH4;!(;C8#(+,)1$H!E&/;5#?A+.C&8)&AG>44-:$FAF"F.E!"B#
@r7902
NGCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTCTTGACCTGCCCGTCGCTTNTGCTCCA
+
!!+"&+#)!$))!#"&%+&)&*"*%)%%)*'!"!$$+$#%!(%))'&!&%*'#&+(#&*($&('#((&+$%#%$!!)%()!(!%"")($)"
@r7903
CCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTCTGCCTGTACCAAANCCTACAATGCCGGNGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACNCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGNCGCCCGGCGAACTGACCG
+
++(%))!$*'++)&*'+&%(+$!+*!)$&'"!(&%%$#'(*%)!!(!$*'+$"()("!'+%++%")$+(++*!('#+'&$"'%"#$'&&!(*!$!+'")#*%)$)'&)*"!$(&$(%))*!)+!("""+#+#'#$%$"!&")"%&%*#)+)"(($$%)'*"""'(&"'()#$"($)($!+#*%&#)!'!#+(%(#)*'+)!&""%++$+$&%!('#$#$(("'(*')+&"!"!+)#"('*')!&%+"(%+#(*))!'+
@r7904
AGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGC
+
1.+-;@#5#GAF./"7+,5<#EA@/*8+,066G+G1?:E,"88H171'
@r7905
AATCATGCCTNGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCAT
+
*1%*#@3EH!<%=H'+?3B(HB</&B@)-(+879%CA8E%2=%A,H6"/%4
@r7906
GAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGT
+
4;")7E8G:.?8<0/B)ADE)E'E=#&$0<3'3;))%>)@)(;7EE#A.=:8@D"/A1
@r7907
CCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATNGCCCACCGAGAC
+
@H%H$',1=4%H26$=5C6H8'=>ECC=A(4&0!9B*&-!;2!1.0@(GB<0:@0#"(*@B!)%-BE/'BF=
@r7908
CAATAATGTTATTGAAAAATGGAANAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGG
+
C./B+6!%>=:*';C#1B7'+@@!8>-C1B-;6H@'14&5)&%2DA42(*A2F&,31-:'?8>4+6!(5B+$8-2+5,(G#6@2B+6,A@4=:HC?3'"8)F2AG=,&E3
@r7909
CCNANNCNANGCGGTTTAACATGCCGAATGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGT
+
%(!$!&#"'*$"+**($##'$))$&'%&*#&##&*+&%*#""#(&&#"))($%((&'*$&*+%$*'+&+&#'#$#$&"(""$)&((%+((#*
@r7910
TATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGA
+
/&@6"'9&@+F<7+-7#!$0,G/+8%HACCCC5$>.*F>'G'$'#A"6"<3A8*4G-4>#53E=#/
@r7911
NNGTTTTTTTCGCATCACTTTCCGTACCNGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCT
+
#'(+'(#*(*%!!&(**#%*#(!$%*#%%&"!+&%)&*!$*)+*&#&%*%!)($%+&!*$!%$&'*$**'+&$)'%"+#%"&#+$*"'+''%###'*&()(*%&&*(
@r7912
NNACTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCA
+
)!'+,A312H1+#"88:#C+69F+!"2H2*-..1,>D:%G1)D;8%2$71&&7>$<2=97FD1=&A!-
@r7913
NCTNGGNCGGGCATTGAACATAAAANCTGATAGCACCCGGAGTTCCGGANACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGA
+
"'&&('(*+)*$'+"#$')#&!%(&$++($$(*%(%%'#%$#'"&'"!#)(&+'&#()!"$*)*!'"+"$$*$#!!(*&*#***+#*(+&&+()%&$'#"'$#%"$)
@r7914
GGCGATTTGGTTGATCGTGGTGAAGAGAACGTTGAATGCCTGGAATTAAT
+
D?*BE$(?';2DH$H5@?-HB.%'11;1<:-11,CBB$-#815%E5BF,(
@r7915
TGCAAAATTATTATCNCGAGTACGGTGGAAACGATACTTGCCCTCTCTGTACAAAA
+
7111"9B-?=(8G3#BDD&*8%2.64(3<<%087*;!"86,>2;A<6+*</0G(F%
@r7916
GCTAGAAGTTCACGTGNGTGAGCNCTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGNGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATAAGTGGTNGTGCTCT
+
*(+*)+!%%!#!*"!%''#'+'+#%!!%&'#%&&)*!&"%%&)$(*(#(+'()""($%!*#$'(#!$+$&)'*$("!'!!'%%+'(&&#'%#"%($%&#$(&#%)+('%((""%))#*$+$))%("%"*)"&)'$''#&"+*$')+%)&%+"%&('!$%$*$'#*&(
@r7917
NGCACCGACANNNGNTCTGGTTATCGAAGGTAAGGTCTGGC
+
%&*(#!*!"*"%"!%+$*+%%+&"''')"'"$&"(%)&)+(
@r7918
AGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCANCCGGACTTCAGGCCTGCCATCGAGTTCCCGC
+
C+6*(E@.;&2>.+<86#FB*3'.E0D3'3610!)C0E?7633"@'>-6.5"+,+=0E-DGC:/,1H/!"4C$$:*?>%-5&+$H$.7$F8=0<!E6?')$50:=9,D?/=61.,AHG/*?>(!5154C*&B<=16@#;H7CA?):H'.760@<,3C.#259-()/#?F-9&E+-!'3,*-8$C@5F(9D?)B2.2'.9
@r7919
GTGACGCGCCCAGCTCTGAGNCTCAANACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGNATGCTTTTGCTTGATCTCAGTTTCAGTATT
+
G+E@.F?1-=DB8@E#@FG<3<35(4(-3=*7=&=$9EDECD8A;<()#1;#3:,?:CE@-#&GE4#/:;A+!B%C5#=<?F*7+4;.'=:6&98A9:?%(&'B*%-;&'<H*4B&18,>%4C*<!/#3$:!'1HF3E#H+*3560"$/5=;05/!)#(,=.E.'
@r7920
GAAACNTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCAGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAATCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTC
+
6,%:A/#F/=)8;8(6</%+E=&#->A0;"B.4(%F#!6HE"?5/#H8E50@(F&6D,C,-:<.2.08"H0;2FDH/:3D3&8>;+;A/C1DEC.&8F&+$%*A1:9G&C1="-:/:3@;6:=&%)2??7(7&>$5*,<C*,("3FF7=C@G6A5>B*;=B7@86..$4:C2
@r7921
GATTTGCNNNNNNCCGTNGGTCATNCCTGANGCAANNTTNNNGNNCATCTNNCNGTACTNCTNNGGANNTCCTNCCAANTANGNCTGCATNTTGCNATNNANNGAACNAGTGNCNCCNCGNNNNNCNNNNNTAGNANCGNNAAGTNTNGAGGNNNNGNNNATCTNCTNNTNCNGNCTANANTNANTANNGGCTNCGAACGTGNCANNANTANNNTNGNNAANTNN
+
!"!#""#!"!#"!$$$$###"""""""$$"$#"#$!"$#$!#$!"#"$"!$#!$"$##!!$##$"$#""!!!#"###$$#""$#$$""#$!!#"$$#!###$!#$!!##"$$$"!!!$$!$"!#"!"$!!##!!$$#$#!"$$#""""!#$!#"$"$"$#"#""!$"""!$$!!$##!#$#"$$##$!#""!"#$""#$"!#!!"!"!!!!!$!$"$$!!#$#$!
@r7922
GNTNAGGTAAGCCACACGGTCAGGAANGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCT
+
#!)%&+#!!''"$*"&!%!&"%%(('+*%#%)&)!&*')"$&&%)")##&"&$#)*")&++%(+*'$$"&'#%$"+"$!)&*()*&%&''#$"+#
@r7923
AAACGCCGATGTTTGTGGCGCANGGCAACCAGATATTCATGNACGACGTGTTCCTGAAGCGCCTGACGGCCCCCAC
+
EE&E&$19B#8,A"-%$)/<A:6=7,<3:''G8;#+68"";FG.<#487/B7CH>F=,4%$/:*(79>3/D-+%#(
@r7924
AGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAAGACACGACGATGGCCACATCNCCATACATCCCCTTATAGGACAC
+
5(5#D0!>):('5*2A;'AD25H@9A8;>DE<5D;&5=#'$D$8"5(F3>+5+)')#<$0/8B&2:?0>3#*4+.,6$G%>6,A;EA::'6B9")(**>.!!,="#?!3.C?5E8=G:E
@r7925
TAATCCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTNTCCACGCCGNAGG
+
D"(27)"77.H+B!/*0@94'1!&:*2GCC#$(EGC>/=D'(50B*2=6'AD71!8G;
@r7926
TCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAA
+
85B67E$=6&A"A8)*+$8)9C&*981#>$'D:<.;)G4+A*%,B>)=2
@r7927
TCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGA
+
AC=F)0&"EF5(E!(.+F)!&D1F%:'@5F?!BG524BH;:-H+#@&<"'C2C&3*:B06,><*"6!87/?;BC-/=43"F@-G10%@/A>E#3@%6('*3G,3
@r7928
NTATCNGTTGCANANCNCANNAGTNAGNNGGTCGGTGCCTNGAGCNACCNNTGNCTCCGNCGTGGATAATGCAGCCTCCCCCCGANTGNCAGACACCGCTGAACGGGATTATNTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATGGAGTTGCCCATATCGATGGGCAACTTATGCAATTATTGTGAGCAATANACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGC
+
%#**'()'&#)(*$!(%&)&#)&#!$%'*%)($#'(()'&)$&(&()#&$#&*(*$*'%)++*$'"+!**&!*##!()*(%%%"""!$$#$$%*'%$)#(*##%"(+&*'(+*)#(#&#!(&'%+)#"&##%%+'(&+*'&+"")(%$%++#'$)"+$*%+#+%&%**&%(&#%$'')&*(*#*%!('$!#"$")*%'#'%#*"'&+)(&+####%'")+)**&"*+$"!!&"*'%+'#'#!*#&%%*$"%#)&()*%!")#+*")&&'+%"+$!*#+$!%(+&)%!+''#"&+$"%!%+%&(($)"!&
@r7929
GAGACACCTTATGTTCTATACATGCAATTACAACATCNGGGTAACTCATAGAAATG
+
@.0#75;*G00>A9'47%67>9-01"E!,#C&2()C47645>0C,>7@D*@:=>9#
@r7930
NTNNAACNNGCATGNANTGAAGCCNCGCANTCTAGGCGTTTTCATGTTG
+
#*"%&"%"'&!'%$#$#("))!*&"%'%#%$$))#+!#+)'!()+(+&"
@r7931
CCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCA
+
3#2AB!B765$/*7@086,2,$AD,>,+.%;8#1$*&/3&E'C@D%)2&04-*(=+#1,'9;F
@r7932
CGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACT
+
-9&11!A!#6*%&H5F,C26);(1,0?>G-(3:A%F=5HC;:!E?&AF$22?8!:@6%:-D=GC0=,E,B3'@72E,C/)B@+<90
@r7933
ANATGAGNCCGGAGANNNNTANNCTGAACNNNATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCACT
+
*($#*#(('!'*()%)!!#&"$')&$'''!&%'*(+"$"")!&$""+"(#$+""+#*!+)'%*"*$!"#&+'+)!()*)'%#
@r7934
GCTGAACGGGATTATTTCACCCTCAGNAAGANGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAG
+
+%&#(*+!)(!#)'(*$("%&'")'("!$)(#('!'!+"#*!*$+(#+!'*()+'&!&*!$(*#**##*&((
@r7935
NAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGCCATTGGTTTTGCCAGAACTGTTTTCGG
+
2=.?CFA4/<-/$#1-F,(<6C(958=+9*B14*@.?1$!"!)>/<D%*#<99$$?96?2H>.<&(&"=#?0C.@+4E&#&.$#*1(41C&E5=G
@r7936
AAGTGGGGAAGTGAGTAATGAAATTATTNCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCA
+
B86.5/DC!8#'?(3-8E@//A7!BE'=@;6"@%)-*7G")+EF,3::>7FDB67A?)>";;%"7*:E136'
@r7937
TTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTT
+
H#D%F>$FD8HH*4AF"B4F/.@6:(<*E%7C7%))>;B9$".$@*):?D>."7
@r7938
CCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATG
+
-4%@#6<B>#17(25!8GE1+%D)FF4><&3<@,C,+!##$9HD:5H%E'H/*?B:2$CA4(*3!+)<1AFH1'155?>D$E336F)6B:8
@r7939
ANCAGCCNNACNCNNNNTNACAACCNACCGNNCANTGAGANNTNGCCNNCTTAANGNCNNNCTNNNANGCCGATACNNCNTCCCNATNCNNNTNNNNCNNCNNNTCCNGCTTTGNN
+
!$"$$#$!""$!$""##$$$"#!$$#!$"$#$$#!#"""!!#$!$$"""$$##$!$!$"##!""!!#$#!####!!"#"!!!"$!#$!!##"###"$""!!$#$!!#$"!""$#!$
@r7940
AACATCGCTNACTCTCCGGATTAACTGNCGGTNACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTNACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGANCGACACGGTGGCTTTTGTTTTANCCGCAGACACCGCACGAAAGCTCTTNTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCNGGCAGGCGTCAGGGTCATGCCNGTTGCCGCTGTTACCGTGNTGCGATCTTCTGCCATCGACGGTCGTCCCACTGACTTTCACCGTGCGGGTGATCACT
+
%D6-71&&@0#-@F165)(4@*5$3'*'FEE455+#.":;"/0,:>&;"#$=$0A6C>;8*>3>.,4G3-%6+>57D5&8*G!*2.=5%H-79?2(,AHH12H:="37=7GD545"14;-F3)')#B@):GC!;-3:+(,A>1#(@9=)2C9AEDC26%&$D>>72AD=H#40=>(%BF)A0-;D25=;%:2G-CH6274(=%@&*)'@E62>#>B!E/6,-7)@,7C')=>"73(E%GE,:27H)26F*3H-98'G$75*A+;')?B&)H,+180:.H8<F6B40A"A5(F(A(-0*-CE'@>)1505.&#+:%CH355A3H$!4:;:;<3&*A@:=?@9)'428H$5+*%
@r7941
GATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGG
+
>%$-E>+3!#<:F*F<00?2D3>D5);=*<19%%(F8@/-HFF*>;>4
@r7942
TAACGACGAGCNAAACTGGNCANANNGNGGTGACGACTGTCAGGAAATTTTTNCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGG
+
))!&!&&$)*%!"&)!&%!!''*%#*)#(+!+"*'!)&&&!*+)(#*+$!&&('$&(!(&'%!!#*#*'*'*''$)$!$&&+*'!!%&'"!##&')$*+)%&)$#&!'%)*$
@r7943
TCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGC
+
#C8><+:0<)%DBC(&A6@>)=D4&+%C=7;!?2G=1D0!$
@r7944
TTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAAT
+
9<H8A<?38>0,CC#*@B@"D(02FCF+84C./#.:.D&>50&B:,275D6%H@&='+:0;$+?3$(?)BF<%3A
@r7945
AACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATANTGGGTTTAATCAT
+
5!0G<1/A7>E/<'$#BC&+"1332DFDE#4@6A"0E&5<.0F<'*/+9$)",>DFG26B*#!$-5H;4A5/;F&H>2C#B
@r7946
CNCAGTATTATGTAGTCTGTTNTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTNCTCGTTCAGCTTTTTTATACTAAGTTGGCATTA
+
!!+)%)(#($()%%!$'&$#)%!""'*"+%+(!"*(&#*#)'&$+"*!'"$&!%&)''%&#''#'$'++%+(""'%"*$$)!$"$'*))+$)!&'(!*$"&(&$+
@r7947
GNCNNANCCNNTGNTANTTGTCNANTTNNNANGGACANGCNATNCNTAACAANTTNGNTCNGNNCTAGCNNCNNANNATNANGCNCANGANANNTGCTNGNANTANAAGANGNANCNNCTNNANCNANNNANACTTNGGNCNCACANNGAAGNGCTNANNNCNATN
+
#$"#!###!#$$$#""!$$#!!##$$!!!"###"$!"#!$#!$!$#"$##$!!"!"!!$#"$""#"$!$#""!""""$$!##"!!"!###$$$!!$$$"$!$"$$"$#!""!"#!!$""#"!$"#"!"!!"##"$#$$$!"!"$#!!!$##!"#"$!##"$!!"#!
@r7948
TNTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTN
+
&"807FGE:>('5<!9H!D>*?',=41B?AE387B=&GG:0
@r7949
NGAANGCAGTGTNAAACCNTNNNCGNCGTGCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGC
+
!(&)"$$*%!#'%#$')$!'!%!$%$'#&+*&**%##+))&*)&%+""&&+'*"(%!"%(%!(*'*""$""$(#*()%*!"+&)&*%%%('!&!!*++$**("++"&$%&%%*#&+$#
@r7950
GAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAG
+
"B>D&7H263&+,<0B5B!0>+1)1:.F0?-HF7(B&/$G1!C;:H?D%+460/=G?
@r7951
CCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGC
+
$@?AC+4,C+!=E?-G2%@6H!3%0,?>&*)?,&3)2A2;6H-<@D!.
@r7952
TGGAGGCAGGGAAGCACTTGNGTGAAGTGATTACTCAAAG
+
#;53&E,B/5+(.%4959.CH@-+%7$<219C*;#6C<A3
@r7953
AAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAA
+
<E2>=?&-@-&DD"-$F2<,FB!.%+>.6(?2<2A/&=H=3'"A2/3;@EG2!3C.%4*)/G,G=-&=;#*A=G0;"&<=
@r7954
GGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTT
+
/7:C'22?<:!@6");F9'F43E3=,07'6!+@7"9?7)0G@7;'B*33#?.37>6#<5!:;'8G7
@r7955
CTTTCCCGGAATTACGCCCAGATNAGCTACTCCACGGCACGNGCCAGTGCGAACGAGTCGTGGGCGTACTT
+
,15'9)9:,.E#-.!--+:G+##$="?)/60D/&<!)9/%+:1&%8'@4=,681@5EG'G5=A12,+$5B:
@r7956
CNGCCATGACGGATGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGA
+
#$+&#*+!&&+$+$'++)%!)#"+'%&)(%''!!+#*")!$#)$#!#+*#&$(&!!!!&"$
@r7957
NTGCGGGTGTTGAATGATGTCCAGTTGCNACCGATTTTACATATTTTTTGCAGGAGAGAA
+
!+"''(")#)*!+"#*#"*#$$&*)"%"+*$!+%'!!(%*++**&%+(!%'!)($+()&(
@r7958
NTNCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGAC
+
"<G.8=.01F5E&2(+:@B3;D".30&$<(+&+E9H0(83
@r7959
AAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGG
+
&#C,"-+%.G<:.>;$@CC&/51AB;8?GH=#!-'&+:!/2?2,)D:
@r7960
CGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACG
+
E,36;E;?'8*>A7/(E&4(*<7H*6)8/'HE7<#%,?F4G
@r7961
AAGAGACGCNNCTGGGTNTGGANGNNCCNATCAATAACNCNAATAGCCNNTGGANGGGGGNAGCNATNTNNGCATGCTANCCCG
+
#(#%)**##!)&)%(&%*$(&*$%!$**#)$))%()$!#($"()(!(("$'&")#((#!#!"$!"&"#&&"(!#*%*#&'+&$+
@r7962
CACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCA
+
E$:$$#+'.0G)F+/:)+**DC=0,6,4"-BA!/?-;*,(<@9/;GG;8B;2E.31+@BHGC=%7#<='+5=@'CG8*8"*C!
@r7963
ACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGG
+
=>EE<<B=:0'3>8"D;6$&%EA8/A9*#2A3;B)-7180
@r7964
ACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCNGTCATCACTGTGCTGCTCTTTTTCGNCGCGGCGAACCCCAGGGAAGCNATCACCCCCACACTG
+
2&)8;4G@>6?A9)96'"0.G6%BC9F$F,B18)FB@-,3-/$.>0:0BHFBB0.$?G)-<136<6=:F:CH7?25!&4D.+B,D6-!A2-/</F"G>2<(?%<=$7+%'0F@7-&17G9(=/86?7%-(A#*>=.-=8H8C2?.*"=)HF1;H27*=*%%&@FD7:$74./>6:D&H@8D$>;48$G
@r7965
NANAGACGGGATTTACGTGCATCCAGTGCATCACGCANGACGGTGATCGCA
+
!'%C>3/3:@&442"<*F=#3DFA:1G'A&?%=84H*B%"5*3.9)E?/">
@r7966
CAGNGTCCNNGNCGGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATNGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATC
+
&*'$)$''(!$"(!&)&+)&!#$(!(((%$))""(+"*!*%###"!*#%%*&("&'!%'&+"&"&%%("+$)&+$$$))!*+('%"+'$((&!&($&$&((*%"+"&%#+%'+%$(#(&%$&%++%%##(%$+$#$+#&+***"%'+#+$&()$!!*%")&((+*)"$)*&$!*&)*')%%'**%)#!$*))!&#%%(+(($!")!%$%&$+
@r7967
TTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTG
+
45%3':$GD17;5%<9@+21H7/A=:9B?C@4E"5B;-9C:;"9+7(-=#
@r7968
GCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGT
+
G-+@"1@D!D/?+.-1=-4*D073FB-#&=B+'EG4@*1@3F/B'/@A7>3#01<#7E>&:3C>H;F)&
@r7969
TTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATC
+
,2C%10%5H6BFD:>=3G26)()4'G@&*%EB90>89=B#/=<%"?/(E=79A+6%2
@r7970
CTGCANNANACNTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTG
+
)#(&*&"%#*(!+(##*"!'(+#$(%$$)+++%()!&$(&$+&#+%$+!!)!'
@r7971
CGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGT
+
-(<CC.)E=(0?$H<2'!A*B@E%88!>3*#>55GB=6"!!61G0==39(4-:@:'<C.12
@r7972
GCGCCAGAATCGCTGATTCTGTCTGTGTNATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCNGCCAAAGTTGCCGACGTT
+
E55://>;3).)$1--:A#F!)8C5;$'#$%F.3H$074%&#E5A/&!HF15//C:49',#8/E,!-2H1#D91::H6;D/3=570?
@r7973
TTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGC
+
*>>7&==D924$CHH-2C"#6*9@7909BA#H60(<&$6&75E!!C@8146$?1(DB>:CE9=(//)-$G526<3=)1':"2A$?.&+HA#5'H?%.-($:HH+*/=
@r7974
AACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGNTGGTGGACGGCAT
+
>2C46C.D@45E"4*H1>:D*(6G+=?F/%3/16/G*!<%?**'9#$!#57/?BHA
@r7975
GAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTT
+
*D$(F6G62?"?2."):41"@(?'7+"7'<20D8%A*",,E7>-F.H&*+$>/)-"8)<B5!.<<>>&A8@&(G,24@8C)9>>>=55F14.2?E%D@'B22C,C+>;9"?,%:"G'0!H?4+#*=,6&!CB/?:68:)9+9G=
@r7976
TGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCNCCCCCTGTTTCTCCAGCGCAGCANCGT
+
DG)%30*2-%>(30;-2.%-2A0+"G#5-96.A42(F0F,$8F29(967'-+-0H4+4<@C6@5?3181>7A
@r7977
CAAACAGGTGCTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCCT
+
<!*DCC#HAH,*4&;?$9A"H,@:C&90E212CH>9&,.<?D.;*:<>='6
@r7978
GAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGG
+
>F2;8"!6F@//.759'CCC9%27)-+%A13#H/88@$9F/>(14D1H1:H,A?D)4:B%>4(D>.A5F#=:
@r7979
GCTTCTTTCCAGCATAAGCGGCTACATGATACCCANTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATC
+
,BB>'$E'%8(+@@HFA*C04C-%H/=+)'AA$/B@5@-4.457,7,#5?"'*7<)/HG,,/F$*9B?76/04C*)&A*D;?
@r7980
TCGAACAANACCCGTTAGTAACTATCGACATCATTACGCATCTCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATGTGC
+
+)()("#%$%))+!*+%)&$))$*&(*')#*)"+(""*')*!')#(!'*%#'#"(+$)*'"'%$*'$!($$)"%#("!)$&%$*"&'($+)%+
@r7981
GCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGTCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCNCGCTTCCCCGGATGTGGCGGACATGACG
+
-@-'$&*1;8'$2&9!<%/0>7C8$*:H3+;C9+B43DAE).H6(?;%>5G48'.-C?C(33F6E6?:.=0G7&0+*A3=36,)F@73.3&&H-",*F#4!@!>F+#.+*+0C(GEC?-500<5!!"642<23.;$>DC$>"%7/1,:25&;+2
@r7982
NTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTNAGTATCTTACTGTTTCTTTACATAAACATTGCTAATACCGTTTAGCTGAAACGACATAC
+
+E073C'0+-D;67/818;8,&EE2C:/B)*=.;6@3*)!=82C#1<.,&5-B-9#7(E+HB"7(-&C*470+A89;.C08-)%C>"=.%%A@,!03H7):-#7?0C549=0$$7?3566B4!9B2;/>+.,#(':=51E/3D6:)E9+CB2;%19:F@""CF
@r7983
ACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGC
+
@43D=.*@<(48)-75@G=!*7@$#?<'(2!6,6"?19@E11-@
@r7984
AGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGA
+
>+#9A41E?:)=)%%85%9&!"8A!..6A$B;!,%&%<<75;'-?:H>"BF2)D<AD+1!.%?8,;/,AF2E?></$!&1>D@?2D6H,@?#.5.#*EGB3&!,A@@"$/BH?'&3A-G5C(7.<+>3>7,A8'FE6)(5!;<?<:6<H9+<'C;<2C>8G:+,1'"05"$F6'3G*=;D'2-7HH<8!<;.+A';(311@*""E;-5A%F(3B!.EH4*F:7>$1/$A)?E+18&<<D'8#)!G1&)/2022?
@r7985
AATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTAATCAGCGCCAGCGGAT
+
4%20*&(80!)/2&991,!CA-5!3H?H=0%6';/##"4C114'!>$!$<@0D7CG'.::58$"28#?/.0=>:+.=>?D9>2"B:7!D(0;5F=68(#G(3=.4:1%&+1@"84(?6/><C>A;(G,@H/-9,--;3,!CBG$%;G3E47<,09.8G?(>=D3=-+&)@058'7$
@r7986
GAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTC
+
/&3&"/?/H/@/<D@0*(+$"F!'B/88-3>&B@%?6%+/'/46%:E/(+:3B3'ED@A1>-:=!)63@*-@>:@/B,;>/2>;A@G"++%H0<?95,)43@)G8'#G-%A1('=-8.:-(;#33E2,*H1";;,/$7+-E=+$.7-/!)6%<1,5$7*=+=5?)2!7<!B1,:F9B5.911>(5!*@?0)"9++.?"1)!@,0C6")!&3,!E"?G/'D
@r7987
AGGTNNTNANTAAAAGGNNNTAGCGTAACTATTACTAATGAAT
+
'%((("(%)(&()&%$&%)!#"+)%"%+!)"$##**"))*"*+
@r7988
GGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGNCAAAACCGCCCGGAGGCGGTTTCACA
+
%*6A79@2:6*G01(D:&'G3<%&<GCBC0:AE#@B%%%933H;F:18E@16F*H%<G,.A"F9'5>.C,?713?1C2
@r7989
GTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCAC
+
77+2CB$<6/+*9?3G(=@($<6G'C<5H:8-#,)*5%(=GHG.<C-"'9.FBE-!#6B
@r7990
GTCATCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCNTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCAC
+
945F<-A</=,&*?E4<9'C5.%'4(@2,B#!536-E)E<,-:30.A)@-1!9@"B5'):6D-6AA-=A5H@&8.F*$4>)CAA+#+2A(HA#&"<060E6"A$84F9!79"""@)+9<3F:A:@*!A-$7>9A50@>G
@r7991
CGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCA
+
=22F"#.;5/E<G%.+$:F>8D3$B0E2(/2<D6:5G0=,G%H2?6
@r7992
CACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTATGCTGGTTACTG
+
1<<B>;.>5#6?'4.4*,C$9G8()=#GH*8?@.-B;G*!>E$&36H0C1&B%)H"
@r7993
TGCAGGATTTTGGAACCTCTTGCAGTACTANTGGGGAATGA
+
8-7$A@&3'C?/+,$?2,(H?'%=A)CD%G/0/'C#?:1A9
@r7994
AGCCGTNATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATNGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGNCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGACGTCGCGTTCNGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGNGCTCGG
+
FE<B=!:#<0)G9H5)3B.3+&@$?+E0%3)9!2,!91@81<HE'$:?6)C9)3*#DE05+7)6++9)+-E+=!?$;'@*F&)6,GG<!<6F+<F=H;&88D#E7@-3;!?'416B2G69"F,+G+%&6)G)?E=%6$7B/-F>'6#98#%$4,6>B&/4&,,/.<'F491#6"#2*"*(!D;3:?<'-?8@<+1)A%E%4?62:$A!H.H/0)4*1A@,,3$B+(+(14%74"2:?>#%H>(:/GD$D-8@!#8-3))B3-D0%7/.6+9:<",,A8$-/904H?*G02/9CHB0H@2>%56)H!.0618H-/=0*1-,;4/BH-1B/9=<!62=@C@4D)7E@3
@r7995
TGCCAGNGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTC
+
'%()!(!+##)++!#'')')+$**+%(%"&+%#+'%%)%'#%$(%'+&&"%%%
@r7996
CCCGCAGTTANCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCA
+
3%+<<#242293EG>-HH&8E='HDED2+37,:1G>2!-=A5<'E#.6.?93C+:!;.$-0@D6E5$>&7F&)-+B<!@0:(2'+DB,780+*G"0<A!+?%F>9:D'7H+!63&9C;(?53D2"3!540+7(92::8
@r7997
NTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAG
+
&6A8!C.)&B,$A@6#%5B=A&DE2@4'-1*6!)-C"%-H"BB?A=4"%1GD;'H02;H<321$.#>&@
@r7998
GTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGNTG
+
&+/.5DBF;.:%>E*+G;7;'01=6B$1",<CG.*5?4%A-G)4A@.,.,C7*>CF+7;"+F0B/10;"*15EE',*-0+-.6.265:=6"71=@031H%(!F!1G-'#@)/88*?427!'5),3++$E);:,&H%&'2=8)%B747?9F&/B$:5
@r7999
TGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCANTCATANGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTT
+
.F95/*$FH43;1.>C=#!8A.#*-*/&/-3G$3=9'+B<<8&?)/8?)#6"!9B<3622(!A@-#G4'$?(-*B?<2C2A4-A($9*7C9?5H29-&8.&&#E9!>&-59&'
@r8000
TGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGAAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAA
+
!7G%?"9.$$#(A-8$=<#/3$#!**>@@*<%?2B%(./403.'96;8,?4*>&0B-;2<B=F1+6;;*E7-.2G$;)-4A#5)B$-BH<0
@r8001
ATTTCNTANTTTGTGGCGTTGNGAAGAAGAAAACTGTCGATACAGCAAAAA
+
''##%#*!$'(#!%&(#!)'&$%!$+$&$#"')&&&#!&*$$+#'+!+*#%
@r8002
NTTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGA
+
(803+%$8787@,D7,C!/<"48!:B%'-H<75.D<+948=
@r8003
CTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTNGCCAGTGCCGCCTCCCGGCGTCTGGTCACG
+
:@=<<-;49;0FE50C>(D%EA0?!2=3E#;,B/7'5"F&)="3G33E-<67H9B84EA2C)!5,!+2C
@r8004
GAANGNNTTTAANNGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCA
+
'*$&#&#!$!"###))+(&++'+"$(("%**$)$#)(*!+%"'!&!*#)+#)')*'+!)#'!!%))%'(#%*!+(**$*$$('(#(")
@r8005
GGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGAC
+
)HA+"5D,=+)0$F,E..G5-#5./E1.5C1A2?28(0=%-'0@HF?>0#)*0
@r8006
CTTCTTTCCCGTTGGNGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGNGGCATTGCAGCACATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATANGGCTGACAGCCTGATTGCAANATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGA
+
+E(2=E53540#C/(A@2;-8'->GC@55$7-2G//5.'@9EG!.8B3*%B'!0>>'EG&3E4;14@:E/5H:>'-A1A5/6A&'10;8B!@B;B+""8/!9"'A.><:4&9-?EB@FH?B&)2E3!;CD96'H,31@;1;@C!)H0*7!H6ED?E.8769&EHB9G/:F(.$,>:F&DH!6$8B4A.1.;"H!B)*;)17!(2G621:)B$#7?$0'A49:=.<*2A);/15#/:&$E.9=3',<=HE@$;9'#*5=7HBD9=:,>,#</
@r8007
AGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTNCCTTTCTTTTCAGAGGGTATTTTAAAT
+
BG.*=16)H5#342HGBC%<"0#2&9?!'935H'*F6/D/,0D66E$9&&9#:@D+B*+&,'E462@!6+<03F@+G:;$1&&&5:@:7H)85+#'C7-755%D::9E+%F@9%@/C9++F/2'0?#0G->-474-<G;&'FC*=D:&6,$.1C3:+G!=,)2C65E&"H0#ED5#$EHB,@"2/HA6'G3FD(&%-396241-B-!E?+C169?8&$<G6
@r8008
ANACTTNCTCNGTGGTGAAGGGATAGCTCTNCACGGAAAAAGAGACG
+
*"%%()!'(!%%+!()"$+")$*"*$)'&+'$$+'))+('&#!*%%$
@r8009
CTACTCAACCCGATGTTTGAGTACGGNCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTC
+
"=&"D7/E/)"(DD57!!>C#1699/7@"?-5HG'*5&<9)'(,:79BDF:"1125#&>(&-<0,3D()'D/#:$B?,A@F0;9H.?@@*<G5)9B*7C9<4:8CG8&;@=B4#HH%G%*.5.C
@r8010
TCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCNTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTGTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTT
+
97H(;@*;>:A$&;HF09*'9$>36-)1'>2:%B-E90*;6,A(!=5#C*<CH,//597G:%<)=1,F=;C/13<0A:1&:A/#"B?D'-'$6&@H4!)'H6F='%#?=1"/-@88/440=E=4#:!HE<H76#,<E)E/:0/):.>G,1
@r8011
GCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTG
+
4.G9!;"C*8E;9.+<6&&"CB>4HB%17F(&(8;C&=7"4B=2'?B0
@r8012
CGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACNACAATCAGCCGCCGCGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCC
+
@A-0;B"G423$5!A/A64%+..F0C.<#H+!A'H$$>"=@E1/;94C*C-/5E8CA?EE,.<G?.4'!:5@!6)>4:F6*!("4%D2F/(>3G%:74E!)#8&HFC'8$4:0*"=B8=355!D'GB$EB.9H$":D-E+%G:*5.'-+$EH
@r8013
CAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAAT
+
4$7H#:8-F'<17FH9.GA28,@3;7G%'C211;.-AD8-/H!#-3:2=1#9E:3,7;/"4AD/CDDE@>-7,=!F?B#--3,$61)/.AF-+48+?63?A-7!5>:
@r8014
TTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTG
+
((H,!13>.4<.A>28C!-28!A2F01C&)+,C;B0C0F1G<8>53)B&F
@r8015
GAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAG
+
:0D2<(!B>%#4&3C.F7$(>>A33B09F05#%H)00F1%$90E,0/1:(=FF+:&"<G.;,)1EDE!)A<@'H;
@r8016
TCAACGGCATCCACGAAGGCCACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGNCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCATGTCTGAAACGCTTGCTGC
+
F6A<#/2DBE2G!/1#==AD!#(<;/HC>6;'709/%5F!*!##C2(,1/<6>#B=?=&41!7FG?'@&$20(-=+!'1(E,-G$?"'!%(<:0!*3!1E,<-<!7:.%(.E%%!6035"5?*20!#?(9E8E*!E(5*1@,:29+68)G".E/(:&1F8AA33*H@:3+"-GC6,@$4?)E2;2,B4(4+E@1*-F+6+$.('47<:C8#"3&F2";./A?#49
@r8017
CNGTCANTGCNGNANATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATG
+
#!%$*")%$*!"!)(+(*")"%&!%*)##"&)%#'$'')#"#$!)&#"(&%%"#))$#%"("!*$''#(''!*!%(+((#&&*&
@r8018
GAATGTGNTNTACAGCGTGATGGANCAGATGAAGATGCTCGACACGCTGCAGAAC
+
""()$)#&)+%#$#!&(+((*(&%+(%$!*%'#)*'%%&#*((#"""'%*#)%("
@r8019
GNTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACTCGTCACCGCGNTAGGTCCAGGTGCAGGTGTTGGCCAGNATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGA
+
$&!+'#%#)##(*+#(*!(!!'#%%"&%+!'')"$'()&&)&!'!%()%%'**"'*#('%&+'$&*($'+&'$(##)%!#*'&*"*&%!!'+!%(##'++#(%%&$$)!"+#+*!&'+'(*(#%!$%''*+(%)"$$%$#"#+##*%'#$#'$)"'&%'"#*$)(!"%&*)+'&)++&*'(#*(!$+++"$%"')"$'!&&'+%&$%%!(*%+''!)#($$("&#'($'#'(%''!)"+$$"!)*#"$&*
@r8020
CACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCTGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCNGGAACCACGTCAGTAACGTCNGCCTGCGAAGCAGTGGCTGAAACAGTTGT
+
+')$)&!(!$)+(+($%&+#&((!$*'**"!**('+'()$(%"*"*(')$#((%'$!*$#"))*&%#*%%!#"!!#%"!'+**()#$*((&#*$$$)$%#)!#%(*+%$()+"'*&'&!$$$#&!&+&((+*")%)#**(!($"*($!#!#(")#)$"&*#!)&'(%+#&$!'&*$)%&$&"!!$%)$%'!(*#((&*('$+)#$$*(*&&+(()"&!%
@r8021
NCCGCAGTNTNCNTTCACACTCGNNCTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAANGGTGGGGGCC
+
"(%%$*&)!"'(#%($')))'""!+!%*&"!'&")+)*!*&$#"(#&"&+!"+&&&""&'*(""'!*)#*#&$)%+)&($$&$%%&"&"!(')*$"#()'%%(*)%+(!"(+
@r8022
GNTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAA
+
8AD206CC/3H6&963)E1#D#>@;+5.>A7!<A.D">&AF(*G:!*=#/1
@r8023
AGAATGCCAGNAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAANAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAA
+
:72.H5D4%:;B1'=.3?29/E$&A3,,??<$./A-.?0:D+@G6<:/5$+4.@8E,9A6*8>?7*@>#.B)4!80#F/8>0@@AA>=1&=+BE*>#(E=D4DF'%$"4A3%)>6(&>/;74%%$31AB/5.5
@r8024
GCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTNTACCTTCGGTGTACAGGCACTGGTGGAAACCNCCTCAAAGGGTGACAGGNAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCANGACCATCTCT
+
61!/D;)E?<'E"BF&,<>67!8F.=40,E@6A/$9-BF(08GF<B55;@51AG:4!D?@6B3G2H/5E/5/@*748<8H6=&B@G7>)?9%#6.0'%2<3?$&#"G$<$%BGEA#,+.6"3+GG"HA%C&H&F,*G)72F@5!.A>-,4.E?:HBHG"$G'F$"#*$AB1:?8'E9E-+A1DH(D%;=3#1ABC>$);C"&3)3.)G':)B35&30HG'<)FBB"$6?+7@>4"C!(#"HC'/F/9/-":.5)$C7%
@r8025
GGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTACCTGATGGCGCTGTAATNCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATT
+
E4E89";B0&5:@*,$E<!%5F%3E'E@73.*&$,B+#."A+3(9B>&+<H':H.$)+.G,F((2"$;AC2=$+D;?=7.8'13$&A/!.E;G$8,CDA)A5F,".E5F<G/)6>$3@&0-(839%G/%&!G.#G6H!EH0?C2
@r8026
NAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGTG
+
!"+*'()')+*$+&)*&'++"#$!!"(&+($*%)!!*)"$+$!)"%+
@r8027
ATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGT
+
=:C+54B7'(3/DH-D6<>'%<$091%15*3$7$8@@%/2F
@r8028
TTACTGCNTNCTTTACCCATTCCTCACGNTCCATAAATGACAAAACCGN
+
#)('%##"*!#+%$%(*'#'&&+#*$)"$*!%"#$%(%+'((#'&!!%(
@r8029
TACAGGGAGAAGGNGCATGAGACTCGCAAGCGTAGCTAAATTTCATTC
+
<D%-!27@>F(-82.#FBB%D"0G?/.:$!?!;"'",D-4/;>4:D%B
@r8030
NGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGG
+
$5'1-D=&;"GCE)@G59-&D.$F@:(./7G#A&.H&F=:AF+=1C>,D$D)6D*0>49#F:'D
@r8031
CGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCNCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGG
+
@E#48!;90F(H;#/.8%@<!D,35?!&-(GH0!3A24.;G)7&33C+@6@GA)@206''@%/2G?3-4C/2,6>:#1#H7A0''C)$,>6@.61#$6!,35C"67$&.A:GC(G*.2..79'%A*:&(-6"<F/*5@H/E(."9>>->*+$#HG6BG=.!/$+2!>)>,99."0+G(G(0
@r8032
CCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTNGAAATAATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCC
+
;EB>8)3)4G="895EB5<"1/;<HCC:+-/.E+F',,$4)6FF>#!F0:9@2)&B3#<8<5G,7*!H)@,@=3?<EHG%%7H+3=D5%7H:8:!>=@5#<.2(B./7)F83@G#3F?!=CC.*@DC5"47..%;E,&FG%"@#:@5,1
@r8033
ANCNNTGTTGANACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGNAATAACGTTCTG
+
%$*'&&')&)*!+$"#"!!*"(%#%&'#*&")(*'!!+$*'(+((#!&&"%(&+*#!)!#+"))"%#"$(!#)$#$#)$*"'*#"*%(!+&("%$%#"$"!+##"'#(%
@r8034
GCGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACA
+
%A631&G;$&"#H,B2/-"A(5$F.C<;G"F-4#,97'B9//D=">0>0@EA*-@=<@<@;;@E<02-?1$C*6#:8G/&#(+F!9$$"0*590A/D/;?&)5G-G9.B(.:8<*E'%-.287.*$F00*%B74+30D3A:++:H?'4->=?8F@/4-5
@r8035
ACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTNACGGCGCTGGCAGGGCTTTCCACGGCGAAAAA
+
=5E=&>0'7F,/D;-#E*8$4$3;D5B+A"'&-$%;?F$/')6;?=A56B%A"H,@H%,97$$D:@4H"E$0A6FH54E<H$3
@r8036
TGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCT
+
*>=C+GG#H=9(>'+%.B%2$:<.(F(&1"3,"9H?B&@FCEG<!++=;)40$&-4<F$F670-4$9GG3E73G,2?.G?A)E%5->H'%+C03$4D<20?=(A7&-'7D7&%.8,453
@r8037
CAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGT
+
!*+%#+(+)($"*%(+)"$)#"%'&$"(!"(!&$+'*)%*
@r8038
TCCANNTTTNAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGNGGAATTGATTCAAATTCAAGCGAAATAATTCAGGGTCA
+
&#'&!&%#&!'+!&%*$!+&'"+#)*+"+#%&#(+"#!)%!%)&+)#($&(&*+++)&'!#%+!')!$&$#)"*$')*(+*!!)&!+''*"&('("$*$&)%!$("!$%%($%('!!#%'&)&%+)&!!&)$$(#!'
@r8039
NGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACTACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAA
+
!%&>8B,/,$A:/--H+'9@F923D3<<E,=%20;6-F/#85@1A,):)1&6AF=/;C?=;B.D9&HB20(/E.#=?2,6=E?5&<#$E4F0!?"D8..#641F6&-F#F%2@+4+>"B!$9*@4,"%*>/D!2*#H<58@D-5,)2(42'-B;02.>HH'F?;95D)2/F9<HA)&%AE8#<<!.1/5#*A*(?>84@#>H/&9+7H*,-,?G($$23-430-)"/)(*@H!$E-)4?(GC'+%.6:=2>:GE%9"
@r8040
NCANCNNCNAAANAATGCCCCCCTGCAAAAAATAAATCCATATAAAATACATACAGCTAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTNGGCATAAATACCACT
+
"(#*'(&#!***%&+!&*#''$))#)#(*')%&$##'&&$)"$'+&$'$&(#"$*&+'"!'(+!$($'+)!'!&)&+"*#!*%)')!'!%#+$#'"%$!(&#&#"*!"(
@r8041
GATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAANGTAAACTCATCACCCCCNAGTCTGGCTATGCAGAAATCANCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTNACATTCCGTCAGG
+
?+A93!B%'&=/?742E(+./)21>(7=''0'.AH&=4&E+0,<0-@@/7;+7@;%#0D6!/3B2%941)*A45%$'-+G%1F4"?>G-$-,79?=C;@?')HD7D2+?'CA+56</#%4A#!">/:AF5<B8$FF&&?:@*=4,C9&!&-B&:B3G)C
@r8042
GGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAANGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACCGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTNGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAA
+
+*!(&)+""(&+)+#$(%$%&!#(%"!+!+'')+&&))%$'%%('%(*''*&*#%#(!+*%*)(&)%&!')!+!'')$)*'*"!$'#!)'&'$*&%'%!+***+*#'#")+$&"%)+&'##+##"&!'$&(%!"'(*++(%)'('")))&!%+&+))&&'!"+!"$"*&$+*#&$!"&)"$+%""''+#$!")("$*("(!%'*(*'#((+%"
@r8043
TTCAGCCTGGCCCTNTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGC
+
G3(G+"17'F3H-5,=<%"B*!%/,!!#+;(1+%H@>.6$%92+<H#7;D%*<&"F.4%/5.3E$
@r8044
GGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGAT
+
&397C>2>9+!67(*EH0")G6!!#,2D<5A)3>DB#!<;'3;;'7DH;62,.DCB5H$F#8B&.C,=<-A,(5=2&.7>..>8@4793C4H?C340!""!(*(8"&G'F<5H7*4*(&&#9GE(4A5G$,+?B54<DF4"G0D%/4+0#&
@r8045
GAGGCTTTTTGGCCTCTGTCGTTNCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGAC
+
C6@4-A7+;-04;%./7B+8B'ACD58//4?#%D=9E&371E.G):)6!?-#>90)<'B*7&92$*G8@G,?>5'(.'(&GG6!B
@r8046
GCCATGAATGTAACGTNACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTG
+
#!)*%)#(+('**+$*#+''!($'"'%!'%%%%#$+&+('(!!##*'"#"%#&()"
@r8047
NATANCTATCACGNAGANGAAGATGCAGACTGGACTGCGACCGGGCA
+
$)(%&'*#**&)'!&"%!+&&%+'$"#)')$%+$"%"''#*))&""#
@r8048
TTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGT
+
CFB!H3G6<5*F8?$&73G&4B.$:60H&651G*,4&=!:B*+*#/%GA2;8-G=.!!C6F@3/3G5
@r8049
CACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGGAACCAATATTCGAATTGA
+
":C1@3"+.4.3BE73!ED.8?%F3(?%*8G1A8:>%F71<E"D'BDD=2)C0/+)':"%)./3$;"F
@r8050
AGACCTTTGATGGTATTGCNCAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCC
+
.*>&",/EG?9CCCD8H'(3)@::02:E@598DC="$0()"35G;,!2*@A9E5E5'=E=$,"#8&+H#H%4,#<>6!='3G.@GFH<$.*"&@=&#C.5%<G;-B+;;69-48<$,!+#228,-,F5'5);2FF<=AB5-:&&%CB6G>6?
@r8051
GATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTNTTCACCTGATGAAACAAGCATGTCATC
+
.>62H+0C;GC-A@,08%=AG6:H53B&BA7/,-,G/FB=-;@7;DC?1B?8,+%5A<E,=2G%$802E,-A7:"!C&@--/65C/$0FG&?7)5#0
@r8052
CACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAA
+
&,A%"B<4/?9H"+FA7/CG.C-,>10?5@E57.!32C8A>
@r8053
GGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCAC
+
2/F'5%"9,H+.*:3F8*-$//D4A+8+&+F!2!(.G-&8"'$+D&(,C2=;*FE/@'238?.>7,!;C)=0G5B
@r8054
NGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAAT
+
*3")#<!$/5#@*D.@7C665)C)/.7$A18<7(0%!=,D&>/@
@r8055
TTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCNGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTC
+
>//:F;7G*(7&;8*6;6#9DBA98)'.":66)/G3CHGC9;2D)-<;'DC8,E:>?9#*#'505"%615G29-)8)%89AF,B.5CB3.;*#6')#5)+;&@$//4#+"33D;8AH-+:E6*G-'.C<9?H!'+!')@*B2C)?#3CD*;8.(01D>G$H<BF,'H3+B0=!.4<)%9!#%)A:"#2
@r8056
GCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCNCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGA
+
7E%37G%1F.3#H.0?&356#AF7"1F(<HC2)$;C=-0+A:@46)41=H/<!#;"AH,+/E4010?:@C7"&7A%G4H7@('#1GDH81/$?C"!%1<7#B;G;G(.')70*9(4E#C270?8D<+3*$H<+,%CE0%+;*!@-',6(!=.B;+';HA,D&<A5$50AB673!=A(763GADD..3@&D-=E$5#0)>
@r8057
GGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGA
+
0>*?#6#E=>%'<2,1;&:28<%0@*;D0EB?F%$D?/)?HF
@r8058
NGCACACCGGCACGGCAGTTNCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTNAAGGCGTGCA
+
!,7@8!@*468.3'7;!<9(<,,!@G>'-HD!:<1!F&/150<3CH?%!7E*)<B>5-.21G%7?%3?B?D#1$&H$5A!>>D1AF!D,4(6&-G813-'9=<?A1;+/.)'&4,61;F'-5%:3<<F+$G,DF;3@GC.F4,6$(0/:,+
@r8059
GAAAGCGGCAGGGCTTNCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCGCGCTTCC
+
>'$<:8;$0)<8;:)'13&6;(%0;2>%4'B0,:)--H)*H5!F6*H,?.+7.&!G474,*)5,?B@
@r8060
NTAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTNGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGANTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGNGGAGCTGC
+
"C(13.A,&7)&<$"D-2(-0%H!,,'#?=+%H!.F-*&4,E5%"2-26=*#29.!0($H(7-"=*>9(@*1D"'&=57/"0:H@8101&*AB$@%5/4,C<"53":G:$*E?%51FE@>E/8*H$1,7+5:%'5%7385?97!+#5DF(-F.98EE:AD+6&DB)ECH,"<@@+$CE2!C#63E7.!13HF+>2
@r8061
ACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCA
+
>5749338<CH.<.E')/:BFDF83++.6%&C/1==G'4)4(H/F!$C9$$!
@r8062
CGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGNTGATTATTTTGTTAACGATGAAGCGCGNGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCACCCGAAAGAAGGCTGAGCA
+
=%*7E,--7:%=C9/-/)--!F6&!&<*+72/56(*HF=2C/5*$6(E-.E>>C;6&>F*,&4H?E??:5@D@:6F+G7:4.FA)@5.6>1<'>88F(:=<C?%H?F4F=%A9?>,,?*!2%#-D*A8$9FCG-9DCA&36B14@F?'.F$1F7H>%1>G/3%'5$($?;D!;#.!@"FCC#%0C0(7"(D?H;=G@99C;&("?39#DA("11'=6A7>AA1
@r8063
GTGAATCTCTCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTCGANAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCGAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCNTTAGGAGGAGTAAAAGGATNAAATGCACTAAACGAAACTG
+
&#$)&*%'!(+)*()*!('$+%#+$)+&!)+$&#&%&!#()"$")&(!+'#)&"%)%(#)("$%'!((*(!#!+"$**+$'*'!+"$#!$#(!)%$!&*)"$!(&'(%'&')$!"&++*+!%$"!&%&%*%%)!'#!'""(&)'#"!+#&"'+$("'"'#''#!*+)+%'"!*+&%'!)()(*$&"+(($%)&!#!+%&'#*")#'#"")%&)'++!+'#&+&#$&*))%$$'!#!"#"'**$'$"(*')(&'$(*%)))%&#+#+%"(((#*%"(+'#!&$+%#+$)%''"'!)("'%)*"+(&&)'('**%+)+&'$)&$
@r8064
TTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGAGATTAAGAAACAGGCGCTGGGCATCAGCGNGGTCTGAGTGTGTCACAG
+
F%$45/$&.H#;G+H6$"C<#A<A#D("C-,E::,$1BB<61B%'.4-:!F4@G=07&D;'AC1'+">DC6@>1&?.)8!F#=@G'7"5880$"";"<>D(%AB0/CHH@"-63"+9&0*58H.,#!>9B2(&;.6F:"00HF@=(3+8B"A13!<$G:;%(=,!=7./9C4)<08>:%5&8?G;$%(<8-57:*10&BHGA"!"#"
@r8065
CCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTT
+
&G1%B273%$:;$%!C*?!FB@E6D1FH41$F(6CE)@9G%11A?0H-@B-60C<6(:.8;&6A0<(G)@!0:'EA:55#)?).0&1-&H=D14%/B5(+"$;F2H
@r8066
GNTGTGCCGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATAC
+
*"$*+!+'('""%"!+$%'"%#()!'!)#)!+"'!"#)$')!($"!
@r8067
TTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTANCGGTTAAAATATTACTTCAAATCT
+
GH>C>2&@#><16.+6@=5'(-*9*.!8>;D.>3'EHF;B*#*/,B5>FB$H2+@$'E**E"@8"
@r8068
ATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACAT
+
G"5-+.>D3&FFDH'A'>,8E(3-",)="/8@$<.<;D?$3(9,*6@#.%>0+D+?0GG,":,#*6@<3$;8,#!C.)DHD,/24%&8G
@r8069
GGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAAT
+
G:-"45-;24;"5!!6(9<;(B;%=.60(D#GH>FC+?,/,%F!&F:1G#+D)?.9;-$=D"&)6,%.D==9)35A;D>2A4)8.=#4?F/:4<9&3>7=G:1>!)#)=?7E)#?!&$0H$
@r8070
ANNCCNNTCNNTNNCNNCNNNTGNNGACTNTCAATGCNNNTCNATNNNCACNTANGGAGTNATTNNAACATNGCNNTTCNCNNNNNNTCAGAANTCCAACNTCNNCNCNNCANANGNNCGNGCTNGTNNNCNGCNANGAACGCNTNNCNNNNNNNNNNATTNCNGN
+
!#"$!#$##""$"$$!###!#$$""$"!#"$#"$!#!#$$$#!$##"!!##!$!#$####"##$#!!$$"#!$!!#$$$""!""""!$#$!!"!##$#!!##$!###"$$!"#!##!#$!##!""#$!#!#"$"$#$#$#"#"#$"!$"!!$"!"!#"!!$$"!$"
@r8071
TGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACA
+
%.7HA6%<F".'E,&/=#F=0@&,0B*7D/-=F9;+E#2;%C>B
@r8072
TTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTC
+
;B,E%DDA.G5180%CHA(>2B);*+$?F4)6%"8.)F4>H0*'#
@r8073
GAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCG
+
">"!56FFC/$;(9A32$#0C5?D%-8/5>?4!<B4A5>C:!'H$*&AH7B,&(AHF//7;#"?8$H*AG9&,)GGD0/.1B.3A%
@r8074
GGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATT
+
97'=&<2/,-//+GHADDE&"+-G00#:'3D'+*C5;%;E$*(H1!/=380G4=F9%?)21C?%669;2AD%B=D>)H*E*"+F'%>G.!&$#7)4%)26=-B#(E1G73#2H133542H56#69CBF)-%>;BE2>4<.?)5'<4G;,2;"&(E85#!;,A.
@r8075
GCNGNCGNNNNCTTGCCCNCGTCTATGTATCCATTGAGCATTGCCGCA
+
**")"*($!!&#(#('$))*+*&$"#'#&(#$%$()""'(+%'("##&
@r8076
AATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCT
+
G>45)4.%+HG'HF?2.<%#A3H9?A+1-*AH*100@"<4H%F,AE;<601,%C1:>319D9(>?EH:E56
@r8077
GCCCCGATGCCTTGTTCNTTTGCCGCGAGAATGGCGGCCAACAGGT
+
&0F-H:4H5$,GF+2176)3/7!,&#4+1&62E"#-C=D6;-:6H@
@r8078
TTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGC
+
93>=&9E:"71E19=)E-%(A3$"?"1C4&$/0C1G%5D@)C#(("'G8"=0H6+CG;'?#=1C0CCF+=4'';G=::6'<#4A/(4/B
@r8079
AAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTC
+
.-8@#)/E%EE$D<6.C<7EBB3"@9@'17%#851EG/?-E"E"3?4@7*163HF4F*;.F@C:H,3<E7%E)4GBB@5%5$AAAG:/1$G33E1D8=+2%554'1<"1?29HC<%.#G0)0%5(%#3?7F*$G**94.<$9%E+DA:)?F2*&F!H'<-/)7/=7G.B!G?G0E5$0@;'.9270B9G&:!31#A%</$.CH4B*3B.
@r8080
ATGATATTCNCCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCNCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTNATGGTGTATTTGCCCTTAA
+
>1)<?@7DA#/@9@&C#C/(?68%A:F@?,=8.6!>E-&FA7(!?C%A1&BB-;0?/):8:AB%F38B!@>6"A"7G1:+6C.6"B4(4AG/1*8*6A7'3%$H3(F4*,,2G)()4917)/H(FG=@@A2?'$4((E%C9%(B*%.#/&9.B9HB(%60,AHD!!/BHEB5CE)5@/(6C>1B)=7
@r8081
ACCACGGAGAAAGTCTTATCTCTCACAAATTCCGGGACTGGTAANCATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTAACCGTTCCCGTGGCGGCTCCACCTCTGAA
+
=C1.(:'<E/.!H0F2+2D@'5"89@/(5+14A::@.4BD9(9,8>DG?*AE1:C/:;H,70(&+?H6-)7()731*4<#>7'6#(7-)G!0:5/-+.A*;;?=634F/98<%4A
@r8082
CCAGNCAAGAATCCNAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCAT
+
$$(##'*+"!%'##&*'"%!$$'&!*$!!&(&"$!*+*$'""!(''!('**++*)(#%!
@r8083
TCACGCTAAACCCAAAACTCAAATCAGCAGGCGCCGGACGCTACCAGC
+
DA#6'$34A=239"#+#?1'!!3F+C8'07)74G7FB-D):@"';*D*
@r8084
TATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGNAGANTATAAATTTTTATGGTCCGTGTTTGTTCACTCATTCTGAATGCCATTATGCA
+
GC/!=/=/'4;/E!)'#7D2CH+9)70;2,8.+%'&'0*GF4-(&>6:23(F10-,E1BGBG,1*5.38)6G?C05#)G/@!+G$%9;1*%32<66>=
@r8085
GCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTT
+
%>,*.=2;-DG;)F2A"(A$D<'.&0(86FH5)#:E48;EAA*3+:;=3?A4F1%2H#45E<4*3(0-1$'#F>!9-&,"#(1<7,'.@%.%1FE(7<"A#E&;'.04&))5<E2;96=,//"7<2@4!#/25>(%D9?7<8(<*,9F28))CH0#2@7H-"EGGA@D4
@r8086
GACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTATGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGNAAAGCTGCTCATACGAGACACCCA
+
E9#&H4(F4*,$B='!,?)$(,<1.3<#C7G$@/BGF(;2="9('<G$'/,@ED?F=4F:#@=-!9%&?;G;7+'D=2G1D++#=06D4@;G86H88&B+$G0-E@7GA)%'1>;0(#??);$
@r8087
CGCGACATCACTCCGGTTAACGATGAAACCATGGAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGTAGCAGTCANAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGA
+
*)G3->#<D*::>,'F1A5!##=).0#30E"7:.7=?F6D8B":5G)2%0>:;>)"90$85B*@/-&6#-1G$#</42*=)AA43H)(;'DFE?F!F?"71)>;5-0*61)0=B@>9.<D%/B50&"<"1:F,;*<E@@==);;+.2+$%).1<40<(6)G@&)&F6''>9$@G?/*;D!4,?@7@$#84+.73'1;38C$8+G&:628*/C;<#;E-E%G?#5"$:8D#E!<51DE$-6>5,E7+E4
@r8088
GGATTCGGTATGGCTGCANTCTGCGGTAAGCACGAACTCAGCCAGA
+
1+/:G#!#)14F(?*F0GF)2/DE=@&C>>6,F(.!)CH?),<.3C
@r8089
GGCGGCAGAAANTTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAA
+
.<E/)&&;4@A<.?/$$BA8B59-E%8F"!&"'0@E$;B/98@%"E2G-.HG4(/-F6,7,
@r8090
ATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGANAACCGTCCTTTAAAAAAGTCGNTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATAGTTTTAGGC
+
(',B>"F8E<<1"06*2?)"8A/).7G>5>:E;46$-A*-))/9G:B=#,H7B1#+5(E)2/4+F6C1BB?92F(<?F:+A.982'8:;D@1@$F)%+!<4D,7'>A//B%B&B;8<;=3#F&,<@$-:#9EC.2.11B).1.:4,D.B*9-%&G9&2'8,0?1D$$!)70$!(E3:<&@7GFH-6?.-C(G;F<+:!6(>"1'!880G"
@r8091
CGTACNCAGCACCGTCTCGGAGCCGGAGGATTCANATCCCTCC
+
#)&$(!+"'+()'&(*$')(+%!)'$*#!*$%")$*"%"%"*"
@r8092
TCTGTTTACCAAGTTCTCTGGCAATCATTGCCGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCA
+
4<08-%$)"=1+73<?4?G)4(=D80%0,?EB5=B)(7.CG&-!13&-"@1-A$&?)A4%5$DB:%;:67="4D'%@,$':G?-GD,E(8HD$E75DA,#>%CE3
@r8093
GANCCNGNATCANNGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACNGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCNCGCTGAAAGGGCAGTGTTTCCCAGCNNCCTTCCTGGTATGCGGATTCNTTCGGGAGATANTAAATTTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGC
+
'$#((!(""%)%#!+")#*"(()"'!"*(#&*((($%)')$+#++***!"*+&"$)(#!$('%$"#(&#!!*!(+'&)(!&##!$$$#('#%"&%)+")!&$##)#*#+%$(#)$#%%!*'#$+$#$(()())((")$&()%##(++%#'(&(**&(+'''%&)"&%"')(!!&'!***)')#&#&%"#*!*#((&)+##+)*+*)$$)'&)&$)")+#((*+)#)$")$'$*+"#%''!)"#!%$'**&'%!++"!+($%(&!%**(!*+'%&((&*#)&$#)+(%!')(((!+$)(*)%#&'%!!'%+&%)")%'!)+()%))!(&+#+!#(+%)"$#)!%
@r8094
NNTGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCT
+
"/9C/&F6C8()FAB?"00GCH'6#>.3&8$)G33<%'46=D,6!:(E8.9$.!,'2@&-*<.%C'")H<+?%!G/'4#H8;3#,>9#7$0+4
@r8095
NTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTNCTG
+
'*/H?&?/64':8.&9(6<E/H5$7>9!141E%'&?5>?#0%))+.8,?1*;@.G)@?HA)8-G;()2;%#'%?0?(>DHH'3E5>C@
@r8096
CANCTCNTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAAAAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAAGGCTGCCCCTTTTTACGACGCCTGCGGC
+
$*#*%!+*##'*'$%!*"')")*+'!%)$(*)*+#')%*(+'&)+#("#!)!()($(!&*+%#+#(#!'!$*%$'%$#)%$((+'#(")&+)&&%"+"*)'%&%&(!&$!&+"))&('%*#+%('))$))&!%#%)"*#!('&+'&"(%(**!""$$*+")$'%"%&%''""&+#'&%)##!+%+%!''()&!#!(%!'$!!)%#'"'!(!'#('#(#(+$)+!+"'%!'#)*&!&"+*$)!#($+((("!+!)%
@r8097
ACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCG
+
-((H+?7%GH,7!&?/,;"H,'8.)-"E#5C0*:0$4/-%'5$0A/>"F@4%?.#@8E3.**#5!
@r8098
GGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCT
+
C#AB.:C44,!%3:H5A.9:C8(HHF84(8!(:&"5$@=C,D?"8:,FA0D:-AE$(D%<HB.1B+@7+F;$*.>:2C"?HF>E?-1>/G?0@G$)77?HC>"?;8G+:.F8?H:3A18$!@BF:2'@9?F';=)E?!"G:F0C*4>7$5'6*$#)&9"H#,3BG0A2)79B&D/(C#&(H!;A,H@-A-E47@=&
@r8099
TGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTC
+
411C<'D&3=6)!58),6$A,G/=F9$%G=0-#6>*E*/3(@*87>37E@:G$AHG,/>E78!G(8;E%DB%%;H9$A!D7=@3&!%2<+,#>%1>B.A$C1F-"")<>#+B=-+A95.
@r8100
TGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAA
+
"@"!%9;AH!.!(3;:3,4#+C?7=8E!F">8))6<=.1H*5$FH3E,
@r8101
GATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTCACCGCTGTAC
+
HAF!&B;<=?&'AE;0)(EA.=F@++"#99B,=:''!:51-9@-#6".9+B:3-0;;%#C8G8:=8F
@r8102
CGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCANAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCNCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGG
+
*+#*"&")#%$($!&'$'"*#"!'$%'&*#&+'*%*'&!&$*!&$#&'((+#!+(#%"+'+')("!"""#%*)&'$(*&'#(((*%*'*"!)%!($(*'"+#)%!$#)%(!)&)$&%+$&$#*(&%"#%+*)$)%&+'&%(&$)$'&&"!+)($"!&'&(($%'!'*&$$)(+#)&''&%*%&!*)&$)")+*'&&
@r8103
CAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGCCCGCTGCGGCGAAATTCCATTTTGCAACCG
+
E.?F4#1).,574945>&&(DC/)H#6$,7;*7)86=07*#F/,)A>!'-62:40B0:<C!&*733/A,?4"+3?=9=8+<)0&(-@A+.E@0=.C3,A!9*9&@!$+F5%:#37.6&#='<'BAD=$F$(>-=<4$*"H?%;H8E8F@99%HG-5$9',#9$50-,>,8/.2"'C@9)E"D;9$F(7),D
@r8104
AGTCACAAGGGCCGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATNAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGNCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCG
+
"+***+"$"*+)"!&!$#+#$')(%#"&$!$"#!!")!(!+"("(#%&$!'!!$(+!%%+*+#&$)+%%&!##+'&#*#$"&)!"!*$(+(#&*'*+'&%"#&(!#'#!#$(&%*''#!&+%!"(!""!($#"")(*%#")"!'*#+'))%%!#+'+&)+"&("('(*(&(+*+%#&&'!%"%)%(&$(#)%")$(&$*!((*+%&)(&'")*)&%'""*#+"++(+&$&%&&&"')((#(!#)##%#+!##)#'"%&$&'$#!#%&((!!'$+
@r8105
TAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAA
+
$1*88?C2"?C%$7/6=/289>E3!E4%'&/602HCH');@1$:F1F6*/:,?39A!721G6"/)*',!C'(&+"B7:C3F%#
@r8106
ATTNNNTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAA
+
*&'!#$+##&%')%""(+&!$+')%'"#&*$%#!&*"(#&*&&
@r8107
TGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCC
+
-'?F3:>+.8C''(=/6GC.@1-.&C!63HB=C$<)75?=)#H-=,D<%-D1++756G3<G!:5"E+FB-0/C
@r8108
TCTCTTGANTTCAAATAGGACGTTTCTATAAGANGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCC
+
2,*,G0)B9))2;75'*EF)$B8&:0$@$5D.%A2=!F+D"6BD772>;9$@AA%27!9*2F/B961=2&H&F5C%.
@r8109
GTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAANGCCTTCTGCTTTGAAT
+
>:):,#@H85/FE-").GD=?;A,",!&,4"&HCD"0C9>D83)4>(>2,)(E$3H08$+.=*436C,:)E8H-($;0"3'3(8B-9159@67,+(3'3)'78/5.9@94(&.!#<3#H<,3';@+C.AH.*A<82D,AF<90=:++<8$0:!#.F<#B?,*5GE=(*A
@r8110
CCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGG
+
9183:B"%B<C@?'A"*G,F090A7;=09G(""H)%!D:D?F&H>F-=$.D1.4/:F2BDA?;5/CH<%E>.7H1?),*!$639:?&C<&56.;G%-CC)!?/6F@A?6*%C0
@r8111
TTCGCGGCGGCATTCATCCATCCATTCGGTATCGCAGATAGNATGATTACGGTCCTTGCGGTAAATCCGGCATGTA
+
$G?-G0$;D/)35"'*3H#.='97D;+5+92)D8.95(1%C>?5<9D@8(675@:6)?3B5?@-/@F?%#4%.G%3
@r8112
NAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAANAGCCTGATG
+
*7)*"</60"%6)BF@(275$D>#95E.G)F8>.E+09=$0G-=%2)B6,
@r8113
ACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACA
+
:"D+@&#(<E<$GG&+'";$.)&+FE,'6D5G/:D*F<B:("A.><#.4HC8*;=4C2"!F).9(5G9E5=#9-;(-8;'<4<7$"0&&$.
@r8114
AGACAAGACACCGGATCTGCACAACATTGATAACGCTCAANCTTTTTGCTCAG
+
0-;+,?H&.3+%7GF+.>C>&3$1?9+/@+;>-0'C51E-2671#60?+57%>
@r8115
CGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGC
+
"=))G?;"B7,68C7D<$&6>-"F&*#B1-1;G.;3=DC&1B;(:?&:$/*H7A#*&GCB8F>9;'-0:<>.A>8($8G<1,&BC6+*=49)/&0!-.<4,1:-F&D'3?.@+36)')&A-D.:1),*+/,:!=82$'H!E395
@r8116
NTCCCAAAGGGATATTTTCGATCGCGTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTNAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTT
+
!>)18E.#5D"%BHG49,$>7*?>:>$6$>''+)D'/H&'%DGG=(2*H!8/<<5E!-)=8C'@&;3<4!C*8'&5@4(,:E"(CG485+2)*=(2E-&2(EA#=)6=F",FC6#&374>@<2EH$=2G36@G?D;>?G=2)*(1>61F(=?8@!&?(=8#?>#<'.-!"H4=/C,08"(/<B41@;%<3"5A@$/++&H4!E:?D?$"<&)91,%;#2117,E.,,FD"29FB$+"*++A7301<5%9917+H6H,;,&;5;!1/!8/+4+%03&*:0%>#%22C6E!.*%#%68$=F(%93(*A!8
@r8117
ACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTCTATG
+
?GG#"@5BA!8,!#671?8=A=/5DGG)'>/'6!'.5=H9%)
@r8118
ATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACCTGGTTATTCTGCTCAAAC
+
A72?B.A-A3$2;*.09"52&@+&20/4>CH?/*G,&!'@FGD::4-CG:D2A#
@r8119
TTTTCGTTATGTATANATAAGGAGCTCACCATGNAATATGCCATTNCAGGGTGGCCTGTTGCTGGCTTCCCTTCCGAATCTTT
+
+*&*+*'")&)!*($($'"+('#*+*!%)**&'#*#&+"#%#(%!&%)#('%+$')#"*'#)'#*+"#()!)!"+!(!&$%!%
@r8120
GTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCAGATATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGAATAGCTGATAATCGA
+
<.D-989F<$@<GF,>%E&4H0,BFA<23"?39-0;@3>3C;E>.%55:H;-3;@)50@.'<3B7H"4.B(H3>!(,!:E6-E2*;-A*-)>>+E"0=;5>@87$9=28,"=+:-#01"05H68*2-/6;*6A)85&:0CB+#:-$A4:'"1F)G)<G2D5"3:G5E7
@r8121
CGTGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCA
+
%$0)+G+B3/AF*@4.=3&>&@>#E>6'#ED)?&H4(5@3&&27$%A.%81*015CCB
@r8122
CNNGCATNCAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAG
+
'(!*%*'%(+$+"#((&&"()'$'%(!($#)'&""!*#$'!!+#($$"$%&&&$+%+'&(&%('+!)*#%)"$&#%"'#$%(&"&!!'$%$!&))%+#!#!)&$'(''&!*)+#$+%'%)%$%&+#'!#("
@r8123
GTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATT
+
=(93FH24G:E"9#766)<*9!':56GH910?:C5=:,("(D*&F3G"?5B/
@r8124
ATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAG
+
@%%FE"*&8.4C(BE!,5C,2521<E<A&"*664*B<GA4'6#56"$0@+'E/$'82@
@r8125
TAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACC
+
7&07E*F3D1*,/2:7-$&G>G;@;1HD;E?"21A0A@F2H-CB/.!!-'B=?64/H!$,2>29$A3/*'C
@r8126
AATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGNCTTGATAATCATTTTCTGAATACATT
+
)07.*)-4D'-&1C2D>C-EDG,95$0(5B!*?1@";):"?1<<.1D':?H?9*#/>.6F39,)/6.;DC=5.;"3E.-<<GAA<CG(1EG+F%7B
@r8127
CNGAGNNGGNNNNTNNTNGTCCTNNTANCNCNCAGGANNTACGNNNNAAGGCAGAGGCTGCGTNTAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTNTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAAGANCTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTTTCTGCG
+
*')(&%!($'!!!%%"*&($%(*&'&*!)")$*%*"((")"$"''('$+)))$(''"+(''###&#'"(%"+')!!!$&$'%*#)&+%(('$*$"$$$*%$!+'%%)%$%+##%%)($*!#!(!+"($!!!$#"!(&&#"((#&%(#&+'%'$+!'$*&%#$*+&!+!&$("$*&''%#!))&''%&%)'+&%)!"%$&%!!!!'"#$#*#"*"#+#("%!)(%&#*&"+'((&+%!##))#+')'&+'+%(&!#!&&$"(#'(*!'*&&&*%%"*$&$'!$+$($#**+%($&((!$$)"'&&*!&%&)*$')!%#%(%((#'+#$!$*'$*'$&&'&'#*"()&&+$%('"*'"!!'**!(*#)*)("#+&)&$!!)$$'&#!#%!'""'$&&+"!+!%"!&'"$"*())&!''%('%&$#)$("+""")&$'%*(#(('(##%$"""+"$)"("(
@r8128
AGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTATATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGCGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATG
+
6$&E8'/D&"805B>%EGED,3:2:B)F%D:1?$%*!G@&<C5,D4>#C1A9&@8"?:44H4(1%?3AD+&:>F&=F7B?G*:50#<&+55*?97+%$4-,59081&:7$/<!'$)0!(;%-<6A.46"*9DED/3HF$*A,4C/F:6.=8DFA21()B)'(D+)-=(9"*51!7<*,1E6*)9.8"/>?+-7EH(G
@r8129
CCGGCGGTCAGGTAAGCCACACGGTCAGGAACGGGCGCTGA
+
DF@6?C&.B+HH7B::E:$"=#,4+D96?@G?F,:<%"!.G
@r8130
GGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTANTCNGAAAATGATTAT
+
A*4)16<955.BF"+3)4(A'6A,@70F,@=5<??EH.;*E6;++C/(9->!4E)/0%AH!,%1DD-9)9+.;(.G/4!BBD6@F-<BD2C,9#)B#!.5,(C9&1!A/+"G.4*2!=4+.>5*(?G7F,D@,@D@/$'7*=*F#0</G4?#1,;/&)=41(G@3@>%(237=%E.C<<9EH@47(')5&!3<F?$4)/..9C+(H(8+G!/,?&$-?B%A5@&;&A1&&)2/6/E-@!F?7<6!
@r8131
CTTAGCTATAATCNATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACATTCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCT
+
(*?A>1$%(.2D(+#FG7>FD7D>"B-3;,1?*F13H???BBDED9%(CHA;>@A%AB?*E/@C3.!+GG;?/G#H2G6<=4,"G?!-@3!,!>&)H?"92-@B!!
@r8132
CTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGNCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGNTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGCGTCCCGCTCCCCTTATAAACCCACAGGGT
+
5B4*-"=?"=(@<'#5==(,)69%C2$=;4?-A*E3-?E'"-GE'=AE<%:@4@:;*C,.&0!!/F..#*=0,5$,-1@>.,8-='HB)=*#>:C,,G-/?*4#>8:D@&A/0&+(>>DE/,:<D=D@19D?2)E8,=8G,,7>/7&3:.1B2@5#,->.7'A.;:>4E-'*E,=-)(;>#DC>AGC'A-G-:6<6*6A'(/'=#FBE+&A1D+C(83%+%G3%=:"
@r8133
AGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTCAT
+
29*"8%21"*:,DFG;8+"2'/17<$*.7@FC:#@985*!D
@r8134
CGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACCAGCAGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGA
+
A5D:213H'81=5/%::&"/!A/1+'AA%18(#E+:!0?$444'!+-A?)=$"@+G;9;.;D>%EG(7)GEE!,'D!">2.'!6/$#;9$2$%*%&.$9*13?D74A)'/19--;-
@r8135
CTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATA
+
9!D6$H;=(G8"@E2+@!$*(8)'2B,"3)5',B5AE0HA#?%G($FB"
@r8136
CACNTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGCTTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTATCACGAGTTGCGCAGTTTGTCTGCAAGACTCTAT
+
C<2->DHC1AB,)%:&=4F(A1.%-$=-FD@/GH<3957<-63C#8HG&3BH4#/&/*6!?3!FD<9+63"C05A;AHD<&.74B-#,F2;/831G>"*E3+B<A,##*$.+754;567,":E4"9:<C),G#/&.B)$2"0,42E%?:;?#1'%$A;&3E$?C2*&1(;>;A-)=,B;>?<
@r8137
CCATGAACAAAGCGGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATC
+
!%7G&:%@/-/5-8FE0D9C31>"<41*D.&*":7,&;G$@6,F18%F53-@*?#3+,AB@$-F&<2F$6".1=';9+C+D39DD))!@7CBG+BA(2')*&7";$6<@4'"7;@B5F>+0/*0?>:?F!7GH<)*4(?G)DD33@3#3"#A-+4(>0:.4&<H-+B#
@r8138
GAATAACCGACACGGGCAGACTTCACCACATTCACNTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCGGCTGAAAGGGCAGTGTTT
+
7*6DF*$*<2A%(<@91!%73?9H,2:00-?A<&$:8+#8%;$@:,4$;?6%C@%E?>2:A$5:81:+.<;;9<<BH))@5&@+@"F!(A3"'G
@r8139
GGTGAAAGACCTGCGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAAC
+
+"+)%+*&+!$%((*+&!$'("%*"*"(*$&(%)"*#+!!$'$+%)#&&#$*)+*!($$+'&%%&#%**(#(!"#)&"+*+'*"'++(
@r8140
TTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTNGTGGAGTTCAGCCGATCTGNCTTATGTCATTACCTATGAAATGTGAGG
+
B7-7&01!1$==**@:!1.#<HFA5231!-D4255&:84/&?E-0%164A.30"G#-"%6G7E;*;4:=84;7"%,7!*+D#16<:.57B:70F;?(DF,?&4"1@=#B:>CA35&0(<,0=&/E$'5>"2;='2'=85B2.&B#ABG"E9,B,":2;4!7H:&%'H3GC/.-0.7@4B777:@&1,=?1'G,B51CH#2E=
@r8141
AACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGGTNCCAGCAACGAGGTNTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCANTGGCTACCTGCATCAGGCTTNTTTTTGTTTC
+
D89<+)'+F4;4AEDB7A;/&<H'D#:#F&7&(E@*@#+%:3!(4%55'02=.(/6"=)H?)"6.0&''+(E-2)/,H87);6F?!F%69H07"24&)<1E#9+H%<.)+/6'?EA=<#96:4.9<E4A$"%>B#(!DF>>2:1#+7():4>/!++?25?6:8$?:'&1HD#F@(1H?&/7$G7D+;*?$F$/%2.<8/'
@r8142
NGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTC
+
'461#.F1("&>4:HHG#?@+8@-;?A"?#@1=5-6!#B52,<AC<B=?:&)BD1'-)G&)H%:$B3&B396/A*%
@r8143
CGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAA
+
C91;B>*,B0DEB;5&0%/5>."95G08'G!H7GFH.H/-C5)A1C=.GFA=?A;.FE3?.92H4-.&!?>)'/BE$)13-3)4*5*'?0026+
@r8144
CCTCTNNCNGNNCCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGNCGGTATCGATATACATTTGGTTGGCAAA
+
*$#$'!#(!)!!#%+*""&'##$"")()'&(+(+'(%$)'#'$'#!*"+(%&(&%")"'#)#'$*!$!"!$&&&))
@r8145
CNNANAGCNNTCNTCTNCTGGCNCCCNTTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGANTGAACTGGCNGCAGCGCTCGGGAATGATCCAGATTTTGCTACCCCCTTGACTAACGCGCTTGCGGGTAAACAACCGAAGAAGGC
+
'"&%"'!"&!)&")*%&%&$$&#**#"+##*++%'##%%"(+*&)$*'!)%*%#!)'#)*"'#+*%+#&(&!)%%&('#"''*+!(!&$*'&!++($'$+!+*+)+)"+$+%+$%))*!)'*'#)$$'%$))#'$)*'&*&"**+)"#&#+(!
@r8146
GACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGC
+
/CBD8H+#BE;("'G6>BG;(*46.98E&11A:9=(D(34(*;1G=@(FA>#D@(<*#HB@03)(!>%C580/#(#:/F$HB.)C:6'<>82=9:0.4=BF.&7)(B!8C@2AC3G=#-E+GD3'=2F#(C<F=/,;3=</6F+7F</<H252'9
@r8147
ACATCAAAGCAGTCTGTCAGTCAGTGCGNGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACC
+
-;8.84+9-'@5#7-G9?H>)>C6<"/G*F$$$+.83B>!"#!E>C9E?%C54E085H>AC0E$A,B6$'!,G@!0EBH:$;5E-<
@r8148
TCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTAGTCANTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTC
+
".?"3%:<5?,).=3D%FA=#+@48<?%0<:0%<-9*&)1DF;G!@4.(<5%40=2<0E!?*-'$72#5*,>F0>FG+38@)4,@<D:=9FBF$5FH(!8+.=!'+FG$F.#8<0E>2/G'.0<*,$&*=4-"-0+D'#2%?78C=(%$#&,1E3'A!&(1!HB$."H2
@r8149
CCAGCGNTGTTCACACTGCGGATATAAAAGGAANAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGGACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGG
+
"(*!+&%%)+#"!&$")%+#(&+')&#**&&)&'#)*))&#!&"#+#*$#)!*"+&"#+""')%'"(#'&%*(!!#*#*+#!#&%+"(#)%)#$*&")$!!+*#")%($#+(%#*'%&$$$%(%(%$#*'"*"!&)((#%!$+!"$&&(()*#)*"!&''&+)&)%+"+#$!"#)'$!*(*"%%%)#$$$'&#%#))*(#+')+"%"'(*$
@r8150
CAGGACACCCCTCTCAGCCGGGAAAATGTGCTNACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGCTGAACCTGTGGCATTTGTGCTGCCGGGA
+
'C64G;A@H!?0?0&(<;+2#:9<F#33.,(@0=%61GF@+*(1)+;.<0/B2C,@E07)$2%5/+4&11CF4.)!B2##*F&:*AAD:0'F91,1BFA3G;C4:E'74,;7',8DD*D:)#B15*:,9E/A*4E<),144*'B*<:>!*2D,D70AC(<G5+).7%904%8/7?1(.<A'7/
@r8151
TACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATNTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTT
+
83=@$(@E#<1!&!<905@<ACA%'#8.+6>=A#:3#:@&0#68;*/#3+7C"*".<7+A%36-*-8,C1
@r8152
CACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCAC
+
.*G9F/#!*>E-2D5@*<+.319*&%/&$G)&E.4C-3<0"+?17!6:
@r8153
AGNANNCCGGAACGATACCGANGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCC
+
!'#*'#+(!##)()$'"+"$#(&&!'*)$(*)!&(%&&!#""'+()"$%("($#')+$+#*%!$"!&'$(+'%#&'$+(%%%
@r8154
GGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGNAGGCACTCGCGACGCTGGCATTATCCGGTGATG
+
?>>+C9#%?A+?55=C)B156-G%4;2A-.!;@@@?;1:3376)-/>@@1;-6<F*H!7F"F:'"-9*9;%.%'>&?6,6,>A.AG)!&+!7"(
@r8155
NNGTCNNGAGGTTNACNGAANNATGGANATNNNGCNNNCNNATNNNN
+
!!"!!"""#$$""$$$!#$#!!#!"$$$!""""#"!#"!$"$##!!"
@r8156
GCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTANNGTGATTAAGAAACAGGCGNTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGC
+
+#%#&'##)%+*!'*"*()"#$%($"+&'*%($!'")%$&!#(((&$'#"%)$%%""!+!&#)$$)**+")*"&+('"(%(+&$)!($'+$$+'+'(%+'*&$**))%!$'('$')'$*(**'!$'%+%&!$+#&)*&!&"'*!+)("%#""$&#"+&#%&%"*%!#)$%%''#+$*+(+'&*%#$%
@r8157
CGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGCGCTTGAGGATGCGNACACAACGAGAAAGGGGATAGTGCAGCTC
+
*0A.<BH*954@;5#!620H*#40)4>(&<+.">E@<.C##E+9<H"%45.)%"2;4/-=/:F;9?"HH6=$=:G;?E91'HE25"C/19:&)#;25FB=&D5=?E;H0;/.3'$();!4-3
@r8158
TCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACT
+
;>0*8)+("66..?35'##$0$,1G6:B(@/$!FE=+F5&1>33>C
@r8159
GCTGAAACAGTTGTTGATTGANTCTCTTTGGTCATTCGCCCTCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACNCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCNGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAG
+
*E=>F.?#-H1B-)&"<@(9"CE#867+G6*<1-!=>07?)H-#7-=<5<;H.*%<B%F>>9D%04$=;!"H"923*:03#64*1D8'2)GB)-*7F&'&B?A3>4:+=)(-"13FE&F-E(.2<'%$;A>&G?%G(8/7->=6*'#H/?*D.F5<=?1"#"G9A9#?-%5453=*-=37.F6(>*:H6*$4/=',@5G0*2E-<,(G02)0D6;0D510@#$:9F,-A#"</A+&#6<B#8!7A26(*8:>-'<7-@485G-'D'B=(%1(7C>B##('8@F*H"BF3H.D=;"5#@CA@+-1%D84#E.76%GE"0A%(-8>FD%?>#*AF?H22D@-)2'<A;@+HHE$9;,?;E'$BD(?;??/=/%:)=+>4-GC+64"002'.D4=%+-5#B.
@r8160
CGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACA
+
/36(G6%C&D+F.8"-3*:;59EF7A*H"D&/E*H1&A&>
@r8161
ATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGTCGCCGGAAG
+
&(,E$0*6E==G;F4$F6$'H;=;6'B1+/H1,(#/E0GG7*)F+4(':#57C2/30"?;#3<
@r8162
GGAGAGCCTTCATGTTCAGTATCATCATCAAAAGCAGNAANTTCATCATAACCCGCCACATCCACCGACTTTTCACGGNAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGNCCATTAGTGAAACGCTTCAT
+
5E8>?31:3-#-1-:3!5B!>!!8!9$8&.C-;.(<H92DA>=&>;;&BB&4H6@/>:H&.)4!7/9-36A,G<1@-02*&/-((2G'29/0)EEH8E8."B3H<5)=A+2/#BC!-!FF0D:-:(7D/5)C!<>"<EC0
@r8163
GGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAANCCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCG
+
DC)%672.(-:>71/2F8?H&&HA%8C)F:$;';D!?>H24=!$?&F3F.*323.$?8A%F?8D+<@;/4=E;152)/AD&3#H457#$:8=7=/<./
@r8164
TATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGANTATCAATGATTTAGAGTCTGAGCAACNAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTG
+
?4)=+3B-&87=,2'@24$H!HG08&=*">(H%/0@1=:$,%!5)A0/$FD=E)+,C83B/$#)C)+$"?472%0BA:H7A:$6GC%#6+D),9")'*,<858G>59@&3<&4G./(4A/E)DE"-<C@(#@1#E*(6;/"$
@r8165
TATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGANGCAATGGATGCAAGCTG
+
(<C')A:%;EB1<,/<>F8-%>&<6E'$$=A-2$=)EC"D$6(8$96?+(;**;/7,3-G6,E5B06
@r8166
TTTNATGGTGGCTGACGTTCNCATGTACCCNCGTATCGTTTCA
+
(#"'+%%'#*&'")#$'!(%$***(&)'+($$#%)#()!(#$!
@r8167
CCCTCTCAGCCGGGAAAATGTGCTGACCGGACANGAAAATGAGGTGGGAT
+
&E+(:4.F8($DE%))==F)*+;A,C+6B;3E>6$*%C5=7.>G4.CH(?
@r8168
ATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCC
+
8/=:B98,17E9#"1>7!H*;H"'9%9DB*F1E-!@+"CD,6;;(D=82'A*%6A
@r8169
ATCAAGGCCGCCTGAGTGCGGTTTTACCGCNTACCAATAACGCNTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACG
+
-FH1'4FC*D5C8F08#>D$/1(5#D,1+?@#.@B;7+E+"01%7:$=>3=+77")!515E='/,<E6&0)'?$642>C'#.#:;A(*;>)AC@,A!(A(2-&H:$(((:7444&F*50<)>2B,3E-G+>2C5*D'%,66#:6*)5B=
@r8170
TGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTNCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTA
+
=D72"?>/%H909"=-$!5'&+,5@.)A:+;C97)2;G6-00#E?4=E"F5G$*@2.H&F==E9EC!B$1193#9"=740#/83;7>E#,"56>?&=#H&*G&"%"9G43?.+4;@4(:B,HA'@9/<6+A86'H>+:4.@*2>,A56'9<B5/!+<HE>3-",9!,C')<+E<*>
@r8171
GATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCG
+
8+<H.*#H"@<**&7",C"H,-0@6(23&)BH<$.HF#;2B)
@r8172
CAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTNTAATGAGCCGCTGGTGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGNGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCCTTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTAGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCG
+
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
@r8173
GCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCANGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGANAA
+
<'1/AB/!9&,D"1104@#+.#3G7D2G?0+2+%*8-"&=6$@",1F&67G!:%E7E7?$-#%"%-;5@!A'(=4C'3&G4=+.D49C&)7-"!'&")&7%0"($!?4:-1"AG9"(:G(3B+1*?B:.$5;?<$0$85?>@4C$5-9$,+D'75)=8FE3C;B&E'/=
@r8174
CATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGG
+
.@;"#+.D.-4F6C0*BB:$86B*=>,577D<,2F/0:"$=8@"'0E6#
@r8175
CNNTNTNNGNNANGNGNNTNNNGCNCNTNNTTNGNNATCNNNNN
+
#""$#"$##!!#$"#$!$#""$#$"""!"##$$$""#$$$!!""
@r8176
TACGCTGTATTCAGCAACACCGTCAGGAACACGGNTCACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGT
+
A330!7,=5-!")/'37.&/&#;),.1>('+6&,C/::=C'G!E&E=".7)-G&E(2B4@$?4-2-"#-466BH%4G#G%9::H9&>*=E=3-3AEF+6<D-HA(3).:4/FH6(/$32E=!B-!G")')::":?8&/!11
@r8177
TTAGAACTCNTCAGAATAAATATTATCAAGCAGCAAGGCGGCATGTTAGGACCAAATAAAAACATCTAAGAATGGTGCATCCCTCAAAACGAGGGAAA
+
6/C<&#756F2>$<*8'F*H3E'735.'+=G6?&="0%,,>H;,*+;8G.;<H5A"#F54C0)$7/*7@G?F/792'<68")"19CH'@'0F%AHA3=
@r8178
GCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAG
+
/-/3!?B>?C6&1#D08++$"-%:D%A-&).D%()775;H8)>:*&(5'!4EG<%?(.,&G)0*/:;3D%'/+8',(C?!,HD%;D;<G!.86F6%&2GEF=3.H8A$3*8?531G7&,5$/C#%0.!<+-=:;+=7-5>B<7"50*9E@@-'0!22*2*!HG;.EE(7<;;C36?1,!@"?1&D8>,&0;1AF*?2:-,4=,/!9?)"BFHH<,E8DB>%&3?-3.<@E232G=G";0'@.%#&G2B5%G;0B"@&GB6D3834+6'E#3+2FC+E9F#':"@G"!
@r8179
ATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTG
+
9DH7C@G:/<&7+0%B+)=5<3$:-6%F/A5<&17!7;E!H@A)(6F.%5."=H
@r8180
GCNATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTNATGACAAAAAATTAGCGCAAGAAGACAAAAATC
+
)#"10/)%/(1>42<$&;A%?!%%:EE?1D-4$4-609A,"</B4'>/>>5;:/-3D$F?4!@&346:/C2<?B88/'>++/H&B;()/26'=6BHE0D2;7D/H9!C;.".F72F1?AA0#0B4&8!3%'
@r8181
TTCGCCNGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGAT
+
E3/!4/4;C4FC+6$CF*GE:5!7+):;$:-:DC0$5F=$-+8$5/4:$DEEG/)GG#2<98'D"7,04@:
@r8182
ANTTTCAGACATTAGCCTGCNGGCAANAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAG
+
EA)(3,?5C@:8>,>@"<,5.//0@+.1E$A4D2,48E8;08)H2+"(B#",CG+6/4F#/5&$1)'1,#>#G$,%!,1H3-64<8
@r8183
GCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAG
+
-*/:?4H9E@5<(<E6)&5H=H,::)6<C$9$87(G7*<(9?3>;3'$;(.:#!DD6!6++A34+'5
@r8184
AGATTAATGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAG
+
)$#A=E"D!4&G-0<9#>-4$=)@&5H/@1:E;/9';*8A,;50D9(E<GB>&@>;7
@r8185
CAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTAC
+
).2.G6A558+-4+).(E,H@%G=:+*BD.@7G'?DB<E50E
@r8186
CTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATAGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGAAGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCNCCTGATACAGCCCCGT
+
G#;C3FCF2(;+H;3,=BC".DEC.E=7H8-=F&+)!1$?34*">$78:&44E4%8)7$HF&+A54<'2D>?,#-F7;D5&FH1A!-C59@B<EG="?BB.FH);$+7=9B"2"/#%>5E5$2+.G8H24>1+F45,:D.01FH=9H64$+G9.G&%+C%/5A&!.A*>)8
@r8187
CGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGC
+
>%%-@@AF9;'6(#!5B@'9;&C">/3=D#9;5?:-A&;7*:
@r8188
GCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGC
+
=*7=9*6D>?4$7:9$CA*.3*);@GC6&=6H8@C->1.D/.&'9EE?%+(?
@r8189
AACGCTNTTTACATTCAGGATCGTCTTGAGGCNCAGAGCTGGGCGCGTCACTACNAGCAGCTCGCCCGTGAAGAGAAAGAGGCAAAAC
+
21%&C(0-;;5A28"!,26'2?3AC$3$'16*-=1DH-@.5=/&"&0'+/!!**:/83+E,;6D,2:!B374>33/'"(AD9<>!@:"
@r8190
TTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTA
+
H:F>+/-$4@4AHH.CHF3!06!(C).-3?F.:"H(-#:8"7H9E234-+;6A:A92=<H2GFB5?EG2=,5
@r8191
GCANCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTT
+
*H93*"90?B,"0-&.71@=>06=&"+:18>"*8%<:?5"=")+7F.@-27/$21+!1,#@0E(D>H$B"D
@r8192
CTTTGGGATAACCCACTGNTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTA
+
2?+,E>/@=!0*2F0F<%)8EA/<1(2G>1AHBH4-2#HD,<EG+<!F>&,-*'A38##E!:'*
@r8193
NCACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCT
+
$$>>&H81&=0@5-F6@*4317(+@.D4@3/01,2;EC@99B@+
@r8194
TNNNNGNGTTACTANNNANNCATNNTGANCTTATAACGNTGNTATNANCNNNCTNNCNACCACCNNGAGGNAAANTG
+
!#"!#$#$#$##!$!#"$"""$$!!#!$!!##$$$$$""$$!"$$#!"#$##$!#!$##!"####"""#"##!$!"#
@r8195
TCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACNAAGCCTCGCAATCCNGTGCAAAGCTTTGTGTACCACCCANTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAA
+
?1&6('#+($/GDAD:9AH7C-9G@.,#)/##C%%7B0?1H;G#;5C3;DCE?93F(()1!E1$$;BEA;<'#!==7-0%+5;07D3<'15D@D%'5".'2542?()-70?A!F#+@B=-;@#H;%&78)42::$1B/$1))'=F8BH1>1D*25@G$1,-*1++(@DD$9"DFGD:-/2#4(82F1-)6;#+%AF=G
@r8196
ATTTTTGCTGCGGTAAGNCNCATAAAAACCATTCTTCNTAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCACCAGAACACCNTGCCGATCAGNC
+
5)?EHFD1D:FDA=B5B%@C-*D829E33D)ED9#?99?;-B#9)/*6$%-7=/%%,#/;&7&72);6(H='A-/3C>(<G=85DB<##,&4*::8G0FD#94);D90/8G/<DDG:#@0';"/@3"&16$-%DH<!DD:&-=7FDE+(.0E?9;G*
@r8197
GACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCA
+
>'C$4+()>=;53A($/B66D%A1?B8FG(>29,$;A$=D&%.9/C/:8H9!G*&A3HDG&5!6H/064.2E"4E1(84(7-'6>=?G;D:>;2630.2$3>B(?:>62A4*)C:9.?0H?0,3>@HH-3$,1&&*:68+<.&'!3&,8!<529=;9(C<+5"9;3%D
@r8198
TCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACA
+
&7>%3+C<->8;?!<$H,D0(3H@556/!;$<++E8#%>&F/
@r8199
NGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTT
+
"&$(&%+'#$%)#+'+"$%%**$%(&&%%%&''&)&)(+"*(%(()&#))#'*!$+)#+"%$)"+(*'$)
@r8200
GAGGCAAAGGCTACTCTTATTTCATCTTACATTGCAAGAAAANGACATTGA
+
G=&(B@+098=>2)1"(1"&743(&%;0E=2,-9+#/F''HAD<DB%?9B?
@r8201
AAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACA
+
3""C='>>'CE!*#EE9B<;@2?+<1C7F2G<*(3A):53/,4
@r8202
CGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTG
+
5HDFEG2$;+%(758*2-&)@55(!#4-!14G0F8(=9%:)1"2C(8"AE?%/"#;*A!8+BHEC&;DE-#>=8"C;5CFA;677GC.D.1
@r8203
CGGGTGGCANCAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGCCCTGAAANAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGNCGCAGGGGACCTGCAGGATTT
+
+"#&(($+("+(%"%&!)(!$!&&+#'**($&"#)+#"'$'($'!('!&'#'++)#""$!)+#+$$(%&('(*#!"$$+**)%&!+'**!$"*"$)+)'"#&&'('&"&"&*"+"%'+$%%')'$(#+()#"%"#
@r8204
CTGCTTCGCAGGCTGACGTTGCTGACGTGGTGCCAGCGACGGAGGGCGAGAACGCCAGC
+
<6<H%@?/<>.A*5=2>44&BF0%;6@=9%/"H6"<*<F0=EG!"B@'H$$&47(0>HC
@r8205
CCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGA
+
@?'8<)/52,">&5D=*HB4'%4"2.7"02%1D>./;#7B!.E#',GDH*H86,A+):9,4&HG#'B;7*%!B-0?G9F;&/E>)<C1<,:%1!+2"+C@AA>D.1
@r8206
GCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGNGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCNTGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGAT
+
('/')#'HCD,;03.2(8.''!<21-(6#*2$@1:,(G=*#456.+F89D=?:!A2-+3"(C.7;1"H8)H:!'4G9,2"#8-/=$<$A;=,#*E:2$D;G=D)6&*3=?5$;7C;#G#:F$H?03(*%>+HH"1H9/<0A5-?78E'0&B;?$-4FEC(2%/*'%34%%(FA:'C(CH<0F3H7/#G6B5+3F7/.,C5<2:14.'5!(1<)*2>;*A,9FD%*5)-!+:%,29,*%6$=0'%:E9&>%DD18,4H8A!>C/B=)#7(6%4G/>&9H?8>G1.E**5.%*3?HH/GAG*DA(?=/;1;;;:=?<75*B(B:->*76)9?::(>:1AA(+/F;"G/16+"=EG2(&6(1"@6D#D3>716?.##?<
@r8207
GGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGAAGACTGCTGCTGCATTNACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTGAGCCCGAAGCGCATCAGCAACCCGAACANTACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGA
+
=C%,./',4&4:8?+$E1:./<3@>7=8-G<D?711D46>FH%B%3;0*6+/.!B:-<6GA2+>F??;*?1:=A6%%A>HF>2G*,@8%>E#G5B490,8&,9!,"#@:9$@19#+)E,@@6C3?-?"@G8E3E&&+(86<(H(.$HB$($=<58:6:G3)%(3G-?G7"($E6B!('.%C<8&0F)5,F)8%;*BCH/A8=224H664E-2'-$-3;*59HEA19-:%)+C?36)14@:#H<56HF)#/0+&<D9>3;2%C(A$,;.$2.$G11-?&@.7,-77+5BB195/4%0(&=$H'+F/E,*E>E1$:E0%D@!=#'H1C#B
@r8208
CGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATT
+
<0-/!3(?9%$2C<6/;)-*:%%)?.!G:'C!E!2A62H:.D
@r8209
CGTTATGTGAGCNTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGNCCGGAGTGGCTCACAGTCGGTGGTCCGGCAG
+
:D$>$33'-B(1+5##00%0F/&/0+D2GC*E+;"E9"HG(9#&F2F;E"(8+<-*2H(B($"7;4)@92(!05(&51="E"*:7."!E@6/.<#$?8
@r8210
AGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCA
+
D59=9>0?5"2?A>.2)B*31.)?8.:&@?H"0B::;6-A#"-!5>,.#-BC-6<+<+$C
@r8211
NCGNTAAACGAAACTGAAACAAGCGATCGANAATATCCCTTTGGGATTCT
+
**)'"'(+"$'!$*&%!$&++)$(%"+&""*)"*'&*&#&'#*("$+)()
@r8212
CGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCTGAGTTGAGG
+
FG>577>4D>)-6A3CCB4#E>>'F)0>,F9%G-3F5@EF)'G)4)!E1-FH;%<8=>@?4F:89-A
@r8213
CCAGCGACGGANGGCTAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTCCAGCAGAAAACAGCCGCATTATGGGGANCCTCAACAGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCNGGCAGAAACCCCCGGTATNACCGCGAAAAC
+
(:@0:>D>C:57&E#!4%2+"<96%<.C(B,94C7F8=E2;6;/%2#+F5+GH6D;1HG<-!64<!A:F.G'9;("E<<B246:C(:?5B,)F9<-#//?33-DD5$-1G.%!;"'+(7#69/A2@/E4'.4+>:5!D-;G;+H:05?>>"106005=#E;F86)$<&@!<.-0"<
@r8214
CGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACANCCCATGACAGGCAGAC
+
D+B1G$?5CCA<,:>B+1;=G@A02A-!?E%B#8;+@<4F8D7F.,>7@!1.>.(GDC05+$.9/!4!6,F#+&B")?<#!1AC13+4&<1986*9/4D/;4-$?::%*>951)CD=#;-48HGC!C!
@r8215
NATNTAGNGAANAATATATGCTTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCT
+
"!$(*&(")*)++&))%%%#!%#&$%")+)(!%&$'"&)#&&*$&!$&)(+$+%)"!+!+*))&
@r8216
GGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAA
+
,<E=3(<&1@/8'A=D+7B6B"H)@*B7.*9G1)<*HB1)";*.C
@r8217
CTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGAT
+
/>-;"!6DG57<H67:EF*68)'(=**%7$2!/B4!07,7@D#A0!?FC@<@);D@@<)<58*F0:%D@H+$?H2/)(
@r8218
TCCGGTNTCTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGANGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCA
+
*%)$&$&$%('+%'''*$'%$"$"")%"+)&'(!*"*)&*#)%%#*%)$)$+$+#)+**$&!($'$$&'))++(!#)"*#%*%#!+(*)'%'')#(!')#"$$%%!&$"$"+*+(+#)+#$%#"+%)#'&&(*+$$%)"(')#"+*+*
@r8219
NNNTGGNNANNANCAGANANGCGNNGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTG
+
('#&($("'%('$'$&#""&*$)+")&"""&&*"&)$$$!%"+#%#*%'*'$%"'!#!!+#%)+$$#$&"+%)!&#+
@r8220
GACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAA
+
#>C!1/C=6:D)5B2>GC6)1$#E-4'@1<<5*.()B<!!HD/*,,!13F(E<&H=2<6$#07E'4!9F+&??=(+0E
@r8221
CACNTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGNCAGCCCGAATATCTGGCGGNGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATGA
+
"%)%+*""#"*)%+#*#()%())&!%*&()(**&!$%$*(!*(&!*""&+)++#&*$"$##"!&**("%""$)*'!##$*+&+)*&(&&)#!*")+*($*#+#%"*#!%&!!")#(&'+%"##!#)*%!"+$++#(+*#+"#*$((&!+$*$(!&$"*"$+**%+&(""%%+*)'!$&%%('((#&$'+&!%'+'#%#&%'')%&''*"$*+#!%$)&$%&$&(+"!)'+'*')"'&''
@r8222
ATCGACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCNTTAGTGATGAAGGGTAAAGTTAAACGATGCTGNTTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCG
+
1D.0:(7-/<-($;%F%10CD>%E%/#;?@?('=@)6.<77&-1!0(2(?8:)&=8H"5/#)A<75B21:3(F*6A,F/<D"'.D$$-(FBA&0:'H5!:4)A"+;3AH;?><8#E'"%%!!1*/)-');0+-!?2$A)$,'@!*!@*8E7.44B#*,A463CGG?25*@+?3298D6#+/.
@r8223
TCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCCGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAAT
+
-4**::/$"3471&":0?"A/B4<F(*"!'?/7$8%@DB%9>*9DF<(2:75<<!="F%G;!;H0&8=G+C;>39-3843%#.5##H6HA:."41CB<=;5
@r8224
GGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGT
+
'#*+"#!%++'!&""")$&$)!%*#(+'"&$('!$+!#%%+")$#%+(!##)
@r8225
TAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGNAGA
+
/'8!?08@?;?8*;7E;0;9D6E>7;.<0F!&71C2)'#5,"A('2+
@r8226
GTGCGCGTTGNAGGCTCCAGCCTGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTG
+
:)=0%)@-=.=?2%<$,6&7?6G?6?(;0@!935C$9=%$<2H$"(0$(B#B-;+;B27*7D"F#>?)!.65B7'@FD0D!,3D@%13"D;%;;47"E/G6
@r8227
ACCGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTG
+
47A/105/=A;9>-E5!%HDF%3E9'E4G*03@H49E$GC"->+$-D6A?;??;%8#C:1%",1%"20&)<H50:
@r8228
NACGGCAATCAGCATCGTTTAACTTTACCCTTCATCACNAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTNATGTCGATGTACACAACCGCCCAACTGC
+
(+)$'$+"%'%*$*)#&'##)+%(!$&&&$)$"*(&!$&&(%(%$"*(%$%''&$''&!'+$&*#()''!&"%))"&)&!(')*!&!%$%!!))&'+()&))$*)
@r8229
ACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGT
+
A??08<;;*0E>/1@E+!2?"=,8--#HC$2#!E7A-BBB,9%:,#DD)(0)@<)(#"/7@?+
@r8230
CGCTTGCTCTTNATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTA
+
C)'H65!'7*&B!//0?%#G)$7B"0-,$0C9(5.92B@G%B,5+)+''11.2&=",.A9F)<2E0(8!1=4*&
@r8231
ATTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTC
+
'9##GD#9#'B&+!6=!8,0:H99GD&%A*?7G*,G>H!C(.8$+0-<8"/4=4@7B=BD&7?-%D7'*180#');2,C)40G.%7+*&7=/93=@D0">*9(GGA.&?8E.8,/G(0;*#;A$;$+A8+6B*H%-3)2/0BD#-5%D
@r8232
CGCCCGTTTTCTGGCTGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGNGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACNCCTGCACCTGG
+
.8*%4G9F,A(7BD8<2"?*#2B:C*E%@(&;'@,.,'A;?2%(B33E!.H<!E(*:2=F..D"3HGFG4E:>9B%/.$8:GB;6)50+/G<):BD2GHC*9"EF1@(5(6:<-2EC@!+.%"(54&.#26;$.!B166+<,%A0&3C$'&@'%?<:@G"1$CF7H(2<C>"$GEGH1C0FC+F5G:A8##0@'>&?6)
@r8233
ATCAAACTGCTGGTTTTCATTGATGATGCAGGACCAGCCA
+
@!4A&.*2*(+6>A*<E>F'"9)<B4,G0/@2H)*:07#A
@r8234
CCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGNCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCNCGGCG
+
)866?+4"C559B9'!@A$>&5@4!C7-7$'!E+-/EB>1=#FC!E/$10/F2'-E>52A8$F*&/"0.--C/"G79BF$<74"?&@468#+F29GDB.
@r8235
ATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGAC
+
45<D/+",$ED$'D2-6;*'?2AHA1!A@=):@C8<7)(%)
@r8236
NGAGTNCGANCTNAGCNTNNNTTTCTGCGATCNTCNCCNGCGANTNTGCACGATTTAGAGGTNTACCGCCCATGACAGGATGTTGTTTTACTGGTTCAGGGATNGCCTCACCACGGTTAATTCTCGCAGTCNTATGGACAAGCTCATCTGCGGCCGGCGTAA
+
!"*&%(#$#$%)$)**$)$#*&*%#*$#*&(*&&)#*')%&%"$+"(#$%"#"&#)()&''$$!**$&*'%#$#'#**"%*'*)!!)$*+#%+))($)')#!($)%)&#%&(##"(#)&(++"'$&%'""&'&%"'!*&!)&'"*$&"%!$)$"'!#'##)&
@r8237
GCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGANCTGATTACTGCGGGCCTTNCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGNCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGNCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCT
+
+*$+++#('&"%&"&!)!+$(")(#)$'#$(+#!"'%#!'"%"*+)$'+$"!*$'"))%)#&#+'+&%++")%!'#+%*'*)&%%"%)"*"$##"'#"'#"%(%'""%(%+"&"$%))!#!*$*''%*#*+#!#&"+%+"#)("('#'"$!'#('!'"))($()&&&&(!%!$**)++*'''!+)&$&(&)!"+"#'$)*'$*%)%&$))*%'$)&'#!%(%!%$$"#)+'"#""&!"'$"%"&#+%#*"$)+"%$%$'&'$#&&#"&#$"!+#*&*(*#*'%'#"%&$(#*$#)(#"+&#+)*#$'"%&$"$+$*)%)!%
@r8238
CCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGACGCGGTGTC
+
<$=*E*6GG.B/*>'8FF.:*@&:>?9=0??1F61@!#;5C1$:1C''=)0/3%?'(-??(&!E+9==E@"4$8<23)C9.&41-?")'
@r8239
GAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGNACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGATGCAGGTAACCCGGCATCTGATGACCTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTAT
+
;22F#*@<"C-?=@(,7$5(/#)'%$)%)8=$66A,7E%26;C(AB48"/5-$&>&&-95@49%3?$5!*#06."%04&3D%)F93!0D;?E8&30@+%CC:@/*+"?2$@*59C3F&2*3>%56$=6%H<FF6>$4-&G7>'?%';H'/!?8(%>>6>A+&7%@0=D43-"D"<$!1.;@@0&$'H?0@+$@9<$-.=C;18!DB/8E
@r8240
GCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCNTAACTTNATGTTTTTATTTTAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGNGAGG
+
-6/;H3;$,0-!4A&8;3$0*(5H3'A,0+01GA@B70&!H<G13.$E4G??421%-(1=.-9556G.4@/9(<&1:9DF>.H?+/5(-A./="23?2#-7:-=1:9*6)19?EH3
@r8241
AGACGGGAAAATGCACGNCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTG
+
9$767C"A,=F&D.FA('BC(!C>"3.(:28>0C<7$6G$B&F4(6%,+;17#%))>E8,:$8A#"<;B-*AGE<;6.24$FC2)?8==D,&;E5@654@>:-29"C+(')3"&B7D!&04-:@61B(%F'&/75!4?9'-0A"38B<02.A2+$#*,)!"4;$;2,0EED:2"-F<1/*$DHE6>.C=!@)G>8'.9/75750$?BAE;">-FB;(593*/*"4;;1
@r8242
CCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGGGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGNGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCACGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGA
+
D8<3+$B6&+5G';.<DF18DB?52+=<#7;G='8>5+$".@,.F1*18DE7#;?,"-=%<)BDH9G800C+"53F$C.'8/$8-"-=)%F,8>0$==G$G,D#C8!$6H*;;24B<A8C9.%,93#5'3//4(0%:G(10@D0.$"ED-A2%!2/'A*E0.8-F##&EC.)89)8%,E/2FE<)F
@r8243
GNNGTCGCGTATCCCTCGGGTGTGCTTCCTGATATGCGAGGCTGGA
+
D'>47*<-,62/@<750;B:G%HE:%%GF0=')";%!D7@76EDE.
@r8244
TNNACNAACNNNTTNACCTGTTTNCNTANTCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCT
+
%!"#'!'*%!!!%''""'%'('(%&%'*%++$%&!&+"!&+"$!'*($#!%*&#'!&+*&#+)#%)+''*("(+*%(#))&*&$'!(+!("+)+'&$)%$*+!*)(%&'!"*'!&()"&$#+*%$%$(&%#"!"$)+(%*)&&"!*+
@r8245
NTGCTANAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCNCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCNGCCTTACGGATGCGGTNTCCGGCGACAGCCTNACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGNCCGACCACGACNGGCCCGCAGTTATCAGGTCATTAACGGCATCGCCGTGCTGCCGGTNTCCGGCACG
+
)$')'(#+$%#&#%+!$!'+$"'+)&&))#+*"'$"&(+'+*(#$%)(''#$'$&"(+&)!!(**$+(*(('&#+&*")%!)&)%$*(!+'%$)$#"'$)&""(#)&#$*#*)%*$+*(#+'%'(*+#(%#+*&''##$%&'(%)"(&'"!&++(")(*!(*#&&)")&&)%)('$#+%"($%'$+$#&++*#'%&(')*+%)%'+"$!+&!(%)$+)"**(*"$%("(%**$!'&"%!'+'(#*((&&$!+'%%"!)'#'&%+&%!"!*"(&($&)##&("##!'"%!$%!"!#!&&
@r8246
CCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTC
+
B18>+%038&@D8+?!G,B.2H#AG:&F#?',.HH0G38/A"=;>;#:%4<;:/+@(/-5!$+BE(7'%50/
@r8247
TTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGTAGATGAAATTATGGTTTCTCCGCCAAGAATCTATTTGCATTTATCAAGTGTTTCCTTCATTG
+
<5,9E@#,6(:"!@)(2$GF43AA+F)C)/D4+*DHH.+7CD>$3=)#*,0D@+7,H%:B0B1$3A;G1H6DD7"5E;?@:?).0>H&,,B832D6"A"
@r8248
CAGACTTGCAATGGAACCGGCTGTTGTTACCGGGCAACGAGTTGGTGATNTATNCGAAATGNAGTGGTCTGATATCGTAGATGGATATCTTTATGTCGAGCAAAGCAAAACAGGCGTAAA
+
!('%6/0%H':'%6*%:#A':#8.29E6BD+:D3E-6@G:A#@=-%CG==/-D<F<4-5<6?4>5$7'=,>3'G/>06D<".<A9//%<-)%2$793A!?=F-?6G4=>+E!.AGB$);F
@r8249
GCAGCCGGGCATCAGCCNGTAAAGATTCCCCACGCCAGTCCGGCTGGTTGCCTCCTTAAGACAANCTCACCACGGTAAACAATCCCCGCTGGCTC
+
+%$&#*$&(%'%'"")%&"&)&'%'(&"()'!$#))(*!#+&)""#!'&(")'+&*)'!&'"&&)+!&&"+*#&(*$&+''*$'!++%#+"*!%#
@r8250
NACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATT
+
+&*+$*%*&)$&'"#'!&*$%&$'"$$$%$'"&'''"$&++!)$#"++$$$$%!"*"$!+$"#&$$$("'%*#!)+"+
@r8251
TATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAAT
+
8@%G#=43BG2E"CC,39<!8&H4D;@*?A)7G76E$#!1A0@A*574E)<65*!5H*>"*;#H#!>
@r8252
TGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGA
+
:E>F;'3A%4C084/;A%986GB$%""G->9=;EHFF#'73@C35E)<>6.;*@+6>;($&8"!)DC:C6D"2$/%&A
@r8253
ATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCNCAATACGATAGAAAAACAAGGCGATTTA
+
10%&/$$#2D>,*:;89F,CB)9H$7(=7!:#9!;?-B2<F4F6.5#EA@8D/8%===0,<!:4!GFBC"#4.)'E3&'4!*/289.8&0,46.8=&=9.<<#ED.
@r8254
NNCTNTGACTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGC
+
#"(&!''+()+"('$%')&(!#("%"%"$("'!)*%!+%#*##'%(!!*(!+(&"+%)#(")&&(+%!%!"(#!$'"%+&!!'%$+)&#+*(%!$%&&+%"'"%')"'&))+
@r8255
ACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGTA
+
-##%H8A*(D+.'@GC')"%7:"%(?0<07H!)H82;6--'C&7837EC##/@;153?6,1
@r8256
GAGCAGCATTTTGGAATAACCGACACGGGCAGACTTNACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCA
+
&?&,4=;FAA8-F>?,FB62G636'(9B85@;*"?:CBF#-;C$/G&DAD4%59C)6#+?"0)&$5#(@.C%+$5(C');?7$*30*D%D!<"<'=$13D3E91$14&>19
@r8257
TCTGCTCGATATGGACACGCCCGNCGGGATGGTGCCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTTTGGNCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCNCTGGAGANNCAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTANAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATNTACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGC
+
*#'+/,'F.@)E50<@;0=#0@,?7)$*>?0G6/!"F.&&3AAE:+#&HBA(0B)("C2!A<=D3%A=7A?';7$*%&2G/*"+CDE$:/8B0.1,*>:@0:228!*EE7-?>F=.373="8E,)A+?8*7<)+<2@*D1CF,&'7=;*?.A9E:D>FDF7EF40>4/1C<336922&#=$2*EG@'7%84C;'92#H%'!GBH9(1$=:?:(4(-GA6%"32-0H(*;@%>74)<*0-%/0?%*<17A=4#GG(;0**G6;C:-DF=>E2))=+A%F94GC:++4)4DB3A!<E>#7=F6"A)<.,+'4C<A:(D?>19?<"2=#.6'.?-&#/A3/.%>2">$(D0(6-%C19(!>82D@(>66HF%<4";"A<0.83G@A?$#9DF?75=5.+(A50$$7C?<%,)<;.E9?,3/./
@r8258
ACTNNAGTNTNTGCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCC
+
)')"#$&)!*"$"+')")''(%&&*"'&*')%"#)%&#%)'%)"'*%*')&$)%#'"&"!*"$+'+'"&%)!%%%)$+%(%!%&#&(#(
@r8259
TAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGTCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATC
+
!*GD25*3B;H7#B!;$9-B+9B:<-1;*EG"%D)+F+AE,D!F7%38B@C--0*;)61:"0(9-&9"?9#-17(>G2B2D"+F!$3++G,C4%701+@5G*E,%'?)-H:<H$508,+:%8@<),A/4#@<)8%"4-C-3-?-+441H.4"C(*=/#><)B(7,"@1&
@r8260
TCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGAAGGGATGCGACGAATTTTCGCCGCCCCATGAAGTACGCCAACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGC
+
6$>'*<2AE)3)"?*C>F&0+,02C+'>?1-9=/#0*@(>,G494<.*.:?B@84)B>:5:F2<=>/#:2;6$:47)H8A<3>&=2G17CG>A@>+)9%G$@G*>:;<82"9&61.1-*.3D/7GA-">3+'.;4*A,E8(5%@=-FG73GE64.-*"+HH$>6:$<(%:3EG.@2>==;F6!H4@/F<
@r8261
CCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACA
+
/2D1H!413%417.'$6F;D/C;!;=-2@/)CH0;/7?/H7-<!@BG5#A-3H$7('/?D4110G;7#$
@r8262
AAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATANGCAGGTCTTTTTT
+
;3;$"7,193E-%.=,*=D)+A#1%B@?1GH#A4?.(%--:<#6&9$*&&E5!HB7#?46246)F$(C/%+$33'"H6"0,.<B)4;D:%4:&65.()?93-3,$,0$+:%1D!=,;"=B930;E.#E>A/DE:AB!72&$-CD?-3A(F>G726"0#5#'8A(!(:+)&6-'D89-&%<8EEF7<7'
@r8263
TTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAAT
+
+$**+)(#''%)(+#$#(&*$$!"(+*%&+(#)#+"!)("#'$
@r8264
GTTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATG
+
.'@0-%7&4-/43-?%!B2&EDB"C.$8$B(%&<H%4$15<-=B6+24*9&@=!3;'6#A%2:8!GH4*<)1?*B@>C>A
@r8265
AATCACTGAAGCTATACAGGCAAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAA
+
5@H>$>@&:D0D?8*@$'9!H77$<25,8$2B.$>.:3C/9#1#C#A:<3='0)&5@$"(504<H93F,!.B'%@
@r8266
AACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGTGGG
+
2BE42!G#452A%+.4D::@5!+>3-)69=6?6(;E'$+0H=-:/%
@r8267
GTATCCAGCACAACCTGCACGGACCGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGGTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTGCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACT
+
;,1@3"!<6;.==1+/0>5&3B@;!02(@3>=-HE2C#9$!C!7GC34A0@15D$1)@F&3G3((!EE),F!C5'=$"2H$10#)5+@+9)D,E105**<4;04@,9:<C5E=;H?@'5>!%#&-GB+6E.B*?EB9,;.#)+<-0!291,$&'@7*5"%',**F##"D<2&0D%910;E$%.G/-&A8<>?6;+A&(10,)7==8F>:=&DG3):?%6?EG5(9505,BE;28)GC7!2';;!(+D0903G24B+CD70732=69>E00!4..?%/D!=5@G08#=$:":,.F+6
@r8268
GCAGACNGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTA
+
>EE2#<A8?B#5"9<%.>4+@;-<+1E'B@0BC(7;%""?28*8%&-97)4+$>@7+6
@r8269
GGAAAGATTTGTGTNGTGTTCTGAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGG
+
G8'/:4DG<.C6F06486A$):5.2(,';74:B6;-DB(=!3AH27AH3D#$.+E8$"$>);<,G"<7!(:6;1)G+"'B//;D.+$>0@:(77F%%F+?;&
@r8270
ACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCC
+
.')8B'@5AA&A7;F3B-4>'(,!!12.&-8&?/")A6&7?<0:+C$9C:BE
@r8271
TGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCG
+
6C?1'7@%=:7&.450%1#;=F1'/@.#G8=F&E+F&;15H"H14H>%B7,0A&1*4,1@86:.2H-CH
@r8272
GCTCAACNCGCAGTTTCCCTACTGTNAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTA
+
+)!*#"!&%!"$$((+*%*$"!+&&""()#)$'!++%&'+%'&!(!%&+#&$'"$!!##"
@r8273
GGTTTTCCAGTTCCNGAAAACGCCGCTGCACNGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGCTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCC
+
0,BE6@*B6F%017E*=!3EHDDE;4E"3&85E9?1G6?A2<"=D)B@/2=G;4?F+&@5,+2A82<5@$*7:3'+-@<!=6D8$&)!,8!=E('$C9H2&:H,H72@CC:FHF+(<+:/4;+,)+5?H;>,9)<3./G)G;?@A25,E)=7>=8!$/<C3&-%G:$E4G5E=BD9#C5(=:@>>>G#F9D"8EF$&9H
@r8274
ATATCGCCANATACAGGTAGATTGGCTTCTACCTTCACNGTTGTTCGGCC
+
D)<.E)"&)A+G709;<)E3A@FA3?1<&?"6-)-5C0=51,3H-70(%6
@r8275
GATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCNAATCCGAAGGCCAGACGGGC
+
F!+7*1%;D;=A8/>:D);C?6"!8.+!-FG74A)G0A@9*8",;>)A'-D&7"0")&3#>:69B7D'*G2$)D-(.7.:BBA7C0,>6<)5/876-EEH9*68)
@r8276
NTGAATATGACCAGCCAACGNCCGATNTCANGAAGGATAAATGCAGCAAATGGCTGAGCGGTTGTAAGTTCCGCAANAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCAGCGGAGTCCTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTT
+
)+$'*(*#()(($")"*'"#%('!(!%$"*&$+"%&%''$+(#+$#'&'"(%%*%%)"%#!+")*$#("$#"#%(+")&$'*"(&'#$"")'#!%%#%#'&+&*(**&+%$"$'*"&)"%&"&"+&+(%++')"#%)+$)**(%%*'*!)(&+*(&!+('#)%)+*!$+$'(('$"+)&'%!*$%"$%)$%'''$*(&!)"(%!'$#'&$"#)(("'%"#''+#(+))'+$&(+
@r8277
GAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAG
+
E?.:C%41:$.0A"%-1A')23.)9)-<9H;!-5+0<$4.&'=7465'>8>,3GE0>6%62#)90-3#!998C?6C.H$!,,'@="$%D);54H3,;"(0D6H4$$AB<1GG&,9A?20<3H3"&HF@38<8&.>21
@r8278
CGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCNGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCA
+
=42=<':7@=.5EC4=EG#./-<0;1*9$H94'-:?AE-/0.A4CCBG(<5H;:@!"@E4835?#,GC*+6:05<(6E/4"#!$6F&0$G>D>(!985-8"@9G@B/2+EF3?B0<52-$=@,H'.2=!H(&451
@r8279
GCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCATCAACGACGGACGCTGCCGGATTAATCTGTATACCTGAA
+
G;@3AA>)-#F*4?.#=.!.$5<$?-&<298.?;+9A0--!-$5!16H@H/&*+==/@E<-A?:)/2544D8B?%;1:18-,&;-5F#H=5FDD=-A/)4$!,""EA#?%:3(<&@B1CAH"F
@r8280
TTTCGAGCGTTCATACACAATGGTGGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATAG
+
&87G8E(>28)37'"'/4@C%F+"H4H.;*>))CA.7*!>4!E4,0DC2+>#GG)/(*#6@&6
@r8281
CAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAA
+
,/=48*3-B70>3#/4-5#?!/6"25H6;+7<,.5/H/=>1E>"+B>A&#,=3/#..D+=&2<4'97-9C4D;*35"%$8-#,&F,3G397?,2EA*E*3<20)5A%H9.HGH3#3%,$G
@r8282
TGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAANAATCATTGCAANGATCAAACAACTTGTATTACATT
+
F1=+//?3B,!$>3E;&-?15GF8DDHB)4"$.5258(7=*43&23*D:"<-:F;:H3<.58F"B;0+2;.H;'B&-D@4-1B.-+2*'2C1)%'#)*F<:E:B:)52!C/>&"+*+""%78)78,ED)G;;<=?4%.E=
@r8283
AATATCCCTTNGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACNCATTCCG
+
<,5?G6HC91A,""=3(%3A33:.?(8962$#<%%*50/H9")B+72<)2$AH@?@?G(@&#<9F4H58.#&-'D/(E1-2E=2+13662/25,!.CGC80@"09+>4'781F=D%(5E?8#1113D
@r8284
CGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGNCGCCCGAAAGAAGGCTGAGCAGCAGACTCTACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGA
+
,!"?8$F$%@7-=9D-3H.H;C5GCH87+;2@+66/D:.>G+9@5(3"=:06%9H0$D4'B;C?$@23$E1C")!62F2F.89*&F##@*=&D/:?5;.B-%#3$(%5F*
@r8285
CGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCA
+
(60=F&'4/?FA9;.:(2"<!C#%3<15B&-C++#-15<F6
@r8286
GATAACAATTGATTGAATGTATGCANATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATNTGTAAGAGCGGGGTTGCATGATTTATG
+
"3E38@->F6/!-G#7#F+*<$H!?,%9,(ED55>).A?2<0/2),"78B62:11"%>H-/:<56C$H:H&!@8*1E/$:;HD?'(@4.$GCBFFB)$."AC)5!.&6#7)
@r8287
TCNNCCCACANNTCCANCGAGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCNCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGC
+
&!(%'%')#""%#&'%!##'+%%!#!%!)&#(%%#)+*!+%("($)'%'&+')(*(!#"'*&'%&#)%$+!'%"('&'#"*&!()$!'%"*'!(&&&*%(!'!%"*)#&'(&"*&"'"'$*)$%&)#!*!+%"!"(%&$+)*))+#$&*"&'&('*&)$+*(''+%&"%
@r8288
GCAAGTTTTGGGTAGGCTGATTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACG
+
6!>G2*)35B3',+B3F$3F"CE99:'+3'?-*#*1E8"A:-;!3/C&8386!2C(/=/F<
@r8289
TGATAACGCGTCCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGCATAAACGGCAAGATGCGGNGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCNCGCATTTACCGCCC
+
+,'A1@427-"#;60H%/C.4C"(/?5(3E0?+,<0.4BC(0@+?@5>*E/G=H0B<.8:+**?/C#$?$&**"#.C&+&C&!/*,-=82D"BED9+,)'@'D,!H?;(>$0"0B-/<=!A5:>&1(H(#+C9;;A)HGC+3GF+1E<:%!1E1#"2=HE#@03@B6(1-3'+4)D)/('$7$.,C38&2&G#':G<:5A)2:'H2089%.6'
@r8290
NNTTANANATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAAC
+
"($"(#"!+$###'*$$*!&+#(#"('#"+*&%)"*%&"'#')#"*!&&'%!&&*&")'+#!)#'++'%*'(&&&()&!!'!)(%++
@r8291
CTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGG
+
4-H.3B:#$AB(>?A;(1$G(,?+:024?!E5=A$H%/-D/68/B0E'7>*>D,4:013
@r8292
NTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCNTATTGCACATTATCCTGAATTTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTC
+
#?"@BF=:8'/67,9,5'AD;1F.,(-09;C196-4->G4G/D;+?7%4G2-G80='$7;0$E<*"/HD/;39A#0.-"29%+B7A%+H>6%5!1!H<E!/@'&*&(&B,<:(.9$G06>+<,"8?31.37.$>%6
@r8293
GATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAG
+
&+*%*%'+()%"+!&++&%#!)'"!$)#'*#)%'#'()!&!!$*($"('#)$+
@r8294
GGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGC
+
<(>'<=@:%$>.1GC%'C%:4"5#:!6&6#,;*=.<#%.D<5/(1@$!.6$9/:H=$D!8.';
@r8295
TCATCNACGTATTTTCTGNCCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGAATGTCTGGAAT
+
%*&&&*'+$$'(&$+()$**%')'('+&%*)$&++!%('"$+#"%!+*!)*"#%$)(&%'"(*%!$*%'*'#")$'#(*('%(##'*&#'"'#"*
@r8296
ATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAANNTTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCACCAGAACAC
+
8;/45*3:,)/;2)B10!5@#ED24'9:5,('(C,+.?!')GF$;*?4?7#@&A)5>&7G9(-FD>5*C'00D=,H90/GB&9,%5>!(727?7$3:2&$610
@r8297
TGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCC
+
B3(95<3*@4H$"=&A=&@"@,,(+1>H'GG0883,"&.%&E%!#?BFE--=41=.0!$%':19&"FF721E?'(@F:F%)G,%
@r8298
ACANGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATNATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCC
+
<B6&#@D8<!?6-=%3/$8<15%(F,2,CF;=(A-B%,G+8<A"?2&7D39F43$0A*&#&+/%"EH++-/<63E'(A:F0+?40A<99G1@9#*@32,-<3/:"?@45"0GG>#8/9/F:2=1?A=<BD(%)?=754HEC<F$
@r8299
CNTNCNGNTCCANGTNNACCAGTCCCGGAATTTNTGAGAGATAANACTTTCTCCGTGGTGAAGGGATAGCNCTANACGGAAAAAGAGACGCAGAAACAGCGAATCAAACTTAAAT
+
"!%)*$'!!'%!")#!!$#%+")&**$$(!#&"$%()&&*$#+"$)!'!!&#+(%**!'())%+(#+*%)"""%('!))#)+#($&)"'$%($'"'"#$(!((%"+*#)#%%('+
@r8300
ATCTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTNTCTCCG
+
3778/B$(3#=*!05"*384@%@<7<5AE5$/>&:*1F)G<C0;@76/!=753@5)G539?4*"1+,>*6:G-C(++
@r8301
CAGGTTACCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTNTCGCTTGGTCA
+
)=5)%-+H?'>8%F8@%<:#6#$63)/7(,01%A9#4-1.7*5A434<B3$9>FC>@(@(*B9FG'%<0..<*?!&0H$+C/&=;7A6=
@r8302
TTAATGCANTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAN
+
D"%(;B<:D9>)&#,&%%88588A%>-1-%B=>"B2:-8$8,41,-*?'52A0)"#5=#1!A<B'4D,5@8'@A*?1<.<%>/)H(,+
@r8303
TATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGA
+
2C$%DC0H"1CGG++@>6A%'H$(.F30C,3(70"9"HBE"A#F7,6!+H+B%%>EGFB-)G+
@r8304
GTAACCAGCATAAATCAGGCCGCGGCTAAAATGNCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACG
+
7'AD%4"*%:C+F@#A02,/HA61H;??@B;C@&"$.";'5019302(G>*!9D#+<<A$?#BH-$H.-2(63",,H/
@r8305
CATGAGAGAATTTGTACCACGTCCCACCGACCATCTATGACTGTACGCCACTTTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTC
+
308*,3<&A8,*7>>"+/'3;6>*;$"&9"?#",!4"G23,=7D<88)E1,H=$A996C2&-",+:<0@!E4<4,*"F<99*/)65):5,25'DDF?F=
@r8306
TTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTANTGAGTTGAT
+
?31HF7398">2$G,+,D&?@@'5)(*#+!'&B3=$*&/>"-D/4!8;"!"+:!;4H7&?C
@r8307
TCTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGANTGCTACGACCACTGGATGATATGGGCGCAGATAG
+
:H!>G)B*@.A"@@3)C99;25AF/4/+',,$::72G-6:>/FA+(@-.+13E@&4/8=0@.D$G=0>:*?@62-,1,?EC:B0F"6&F6@D)F,)&=EE8($/A
@r8308
TGTGTAAAAGGCCGCAGCGTAACNATTACTANTGAATTCAGGACAGACAGTGGCTNCGGCTCAGTTTGGGTTGTGCTGT
+
?15?=B,!=:4<!>=-@>?H!#6)"=39A:1=A+B1@84G!";730A:-(D#CD2:#9+G42F0=",HC8+=$4@*)*#
@r8309
ATTCTGTCGACCCACAGGAACTGATCACCACTCTNCGCCAGACGGCATTTAAAGGTGATGCCA
+
G)%)64GCHF8F3&H,-A2*%&;2F.&0<H537%62@#>.605D99-0"C14+5?$(1C>667
@r8310
TGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCG
+
EE$C84,6(B4B(;*)7?'3?GCAE/!7,8>6#H;<",?(8DEA:+"H-@(08*/BC9*,B0:E;D2+C7)E.<@!13(0#(0A<:3$'$
@r8311
NCAGCATGGCCTTTAATGACCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATC
+
-8)+;/&797804)<:-:A4,"F*H.HH/@077A$9+G=HF2:DB''(A.6-?>8A."(%3.:D+%17D4FF<$4.)C=4"/EE?7
@r8312
GTCGATTTGGTGCCGNAATCGAAACTGCCTGTTGTTTTCGTCC
+
:B,>$1H'(!F:%%48GCCA32?"!?'8,13"+-FD,:H:B8/
@r8313
CTGGTAGGATTTGCTGTACTGCGTGAANAGCGTTTTGCTGATGTGCTGGNGATCGAANTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAG
+
6;$"-?+.<AABH.C=19#-37=1%')0GC9-+>@$:A7HF:2<-&:HC&%06HE,$0#0B1E2)/C10"D%GG<45C>>-'C94?/)+%/$AG0+<'D7%(&G7:&$%&9-45<BB.-(!F#;A;9-9H'#!=6-G
@r8314
CCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATC
+
@"='?35E166/6C2BG/C?=5.'HC27D=%F->.&,?)6?:1#H
@r8315
GCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTC
+
7')$#&B%#BF9;:??(8=!7,8/$@$5!F4+:65#6B#9:/=85829D+;.6D@40G37-466A*76,GE!F4.
@r8316
NCNGNGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACG
+
#&"%%+"("')#&+&!*)(!*%$!$++!)($#'*((%&%'+"++)$&"*"!**%#+'++&
@r8317
GGGGGTGGCNCCCCNNNCGGGGCTGTGGCTGAGAACTGCTGGAGACGCAGNCCGTGG
+
(&)*$!%(*#*&&%*&"&!+$('!"!(!###%$''&)"('(*"!++('')+'))*#'
@r8318
AAGANTTTTNANGTAATGAACCACAGATTCAAGNGGACGATGATAAATTCACTAAATTGTTTTATGAAAATATCCAGAAATATGTGCTTCGA
+
$(''#(((*%)$%)++*""$"%!'##''$))!&&+*'*)%)%)()"#*())"$+!'(&###(+**$$!"'!+!#"#'"*")&+"((!+$%$#
@r8319
TGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGNAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCA
+
$26*.(13@A61&#?$E,.1=@H*8+E3:(D>#;+.;>"H=?+@3%CH65*@%C82#*DCE!H$B1"/2H,%6=@;9/8"(3%*$+28$3)EEE$0>G1102!$5/-A.C"5-#$)7+>.>H1%;5)>=E;/62A,7C#&
@r8320
ATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCC
+
4&6F)(&2A8CA4(D.?!099)C==+?E(8016@"9+/<1"G8F(<HF<E%:;1",/;F3H=.C+-'6C#5D-,$"-&/&9?#-='&00E4<8+@=*=?&#@#=&G7;1%5)$D0;A%EE)2&0)E/-9G%*:,)."0B<)2=6F.-;=F0BH
@r8321
TCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACAC
+
>/B!%41*6+F;6*B2!&H*1-/@(!()*,:+-"*BDGB7*+6C#B
@r8322
ACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATC
+
)CFE1.;*(2/9>?A!<B0GFG30B1>E:>2AAC+;94-<E@FH8$26:"2;!("9CD>!,C+;9#EA!'H.06!%!BG
@r8323
CGTCAGCGTGGAGGNTCAGTCCGTCACCGACGGCGTGNAGGTAAAAGTGAGCCGTGNTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGC
+
0AA7$9%5.%$/6,H)%7A,2*@=9!.D)D8,-C<D2060#E@@+#B7;@B&G6BH<.",H:F$2(AFD#3@A>7'8)'*H8@CF?(4(2H;/D%,%&A7+;!>%(1G;E8$$1@&
@r8324
ACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTNCGGTGNCAGTCACTCCGGCC
+
5&5#E<0<C:A#:&1%6&#!@H-90$.)$@)D:'#'@+H"B-'<38>(,C'FHAG@(?G+3"3:'9
@r8325
TTAAAGACGCCGTTTAACANGCCGATTGCCATGCTTAAATGANTCGGTGTGNANCCCATCAGCGTTACCGTTTCGCGGTGCTT
+
5F1%D%6)(6&966"?&7)D1:G&.CBB..7)6<033,$4%#?"G0C&-8/(-GC44/-7"D">E@E$+GEC+.!+CD?<2?#
@r8326
CAGAAAGATTTGAAGTAATATTTTAACNGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGNTGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATT
+
$C/70/)>-2@5F0((.@D189$2D!*F.9&H+,$C((D4"-<;+3/EG3:B3)0@*)#"#-B./01$/HF'=B<".--*F9>4C8'%/-:=F@;G.D;0,&7(G$'G,G);G>".*?,:>!&!E?E=H6F?-A4#'.))*>1,88!#<(EB-"CBG:&H/>8H("1<5.0@A?'<CA393%$>@,6:2+5?$"%(6E
@r8327
TCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTT
+
>7'';3A((*?618<B,E5@/A5-&F24)8&8:2#=HA+/"$(-
@r8328
GGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCNA
+
H!E48807#7(+?@C#.A(&##$5/<5'?2E(-@$HDB+%35A8?H@8<@(':G/=#"%,?!:%0,134(414A<CB3?
@r8329
AGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTTGTA
+
8&&)(*3G&G>'<*?+%0C-79D*.1<5CA78++E!";:+-<=42A&56A3!H6/6*
@r8330
CAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGT
+
.*H&%)#.A;'=%-!1B4+%-)+&53$2D?1162>C)1836A-@!B'2/$
@r8331
GCGATANCCNTNNTACAGGCCGTGCGGTTGATATTGCGAAAACAGAGCTGTGGGGGAGAGTTGGC
+
%#$)$!!("&$#+%#+($'(!'*$('*&$%)'+&((!&$((!++*%)$#%")'%#*&+)')$$(&
@r8332
GTNGNCGANNAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTNTCAGGGCTGGAATNTGTAAGATCGGGGTTGCATGATTNATGCTNTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCNCAGAA
+
*)"""'$'#'+$'!$'*$&#')'***"(&'&&'(!#(%'&#+#$&'*)*$%#%#'*""*'+'"*&)'+!!)!$+*("'+$!)&%%%'))+"'"($')*)&%#)$+#"#%##+)%('&!#)$(&*(($#!$)'&$*"$#'$
@r8333
TGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGC
+
-H<.(/+8C.2<-(;;;?:/2#=10->&E?ED@&('E0/>D<>04.G@ACE8B#=B7HG'!D@*/<-D&/8A(1.#-,>B-!!D!$9-H>@H'D3031$E8G-03+<%>>-H>;+A-</<&E@@8-)E><8D9;<@">:&F333?4H0!-'0$=D'/>D-:/B;+$*HD%=C/=(.C7*4:F"9>H-8>05:F1GH+@",>A.4-,<-%;F!%('+H!8!.;,.8#G+%&8B>#/7,<G5F
@r8334
NTATACCAATGTTTANCATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTGCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACAATATTGTTATACCAAATGTCATATCC
+
!>33.?4F3C7A8,H>BA7:;./B#$$?;6CDH5-B3<3DD4@G34&55)*.G(00);(E5$:)*ABF5$H'2);5&;7;C?#8B7H;A:')7GEFA(3%H)D)%,?@>!(C?G&2%=813@$0@>8?8F5*0(5,7E$9>H:#""C///:9)FE.H0G"96AEE#D>,E2.A)<C9D3(:H#;=0%?8%</EG;HH3E*10F1814("
@r8335
CTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTNGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATACTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCC
+
8:.;C6%.!<2*&>)7:87CE-(!<.6("7:2H-3(E..6>5=5B=)<BB&%4<7DB**HB;'7>22H(#?(0F2=F8##/>@=1G*'G7+9<,@.=6;4@?C2-2&@,'4!?-<91%!&0$@/G:$C3-GEC)F,CH65D-721B5F'!7'++C)3
@r8336
TACTATGTTAATCTCAGTCCATGTCGGTCACAAATTAAGCGATGGTTTTAAACATAACCTNCTTAATGCTATTCAGGATTTA
+
DGE=+0F?#3'B;0,!F89D/DE)(6099-(;B/F"-;G"5,E81*52E61H6C$HH4045'5$(&+25%1+<+$A)7+:5;
@r8337
GTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGNGGAGCATCAGGCAGACCCCTCCTTATTTCTTTAA
+
31BG6G$E.50<%(@2'/:-8DA<C:A=4$9!9'1.H('%@-=*)G4@E,>F:CA/;>B:9(GH0F5'+.CD17#F@E(,!&9
@r8338
GGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATC
+
(H?;)#H7A+>!,A%-B@"36D-?8,H"?F+'EB=&BH7&G9-B4<*<,?;&%?9#E4B>A@2C8F"12F7H7'?4)CC1=!D".2E/'(4E&"C*F*%@1B@4(0B:F<219"E"=$0'=H(-,.,!.FB.!/G;E#)01F+0#=:
@r8339
ACCTGCTGTACCTGCGGCTTTTNGTCGTACTGTTCCGGCATGTTNTTGGCGATCCGACGCATCTGCTCACGG
+
<%29//!D,0@<?G79!&-4-'(,&<;3#6G)F*;C"3G""CHH+11)G,@!6$8"'+BC#GGA:/98F5DG
@r8340
NAAGAAGNCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGC
+
%'$!)$(#+)&+#&!(%)"'(&+)*&&'$#%"!!$!#&%+)'##%*%+)%$")$&%(*)$'))"&$)!!+'%+&+%!#()%%**()"#+'$'#!$!%+&!#
@r8341
TCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCAT
+
7A=E.DH-&14?HG*?+4,-754%DG'-29>%B.=>?F(>#H(/5!;;$=83;!!+2F>
@r8342
CGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTG
+
#@1%)@D$1B#?50F7(3)*@7H0-!@252>4$A?+/H*HA9><-2E248G=
@r8343
ACCTCTGCCGANGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCNTCTGGATTTGTTCAGAACGCTC
+
+*(#'%!&%#$(*(&+(!#&$($"$!!%')"'#'&")&'))%(#$+$#*)""+"!%#&!%!!&%*!%'"+#((+(#"%)$!+)"*(*+**)$++("%)%'&))#
@r8344
TGAACATGGGGANCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTT
+
(.606C>93)4.?1'8<*"3/-,C>;*(#''$GG3'-;8!-*$2653$G;5
@r8345
ACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCC
+
/1C,>?';"EB'.6H)',&+)G63?2!14*B"+'%.=A<9,B5E56@<"C=4DHA*
@r8346
TATACCGCCCGTCAGGANGAACTGAACAACGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACA
+
5@@4'8=8D&#8A"#G#:?A&7>>*GB;B95%,>HHG*=#:#;)7D(.C+E4,:H(354<8C$A4F$
@r8347
CAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACNCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGNGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGA
+
,(5&FB)"'!!?%=386F/G*#471.G"?;)%%::9;A&5H'AH5+C-3<F8&1-*></-..AF@AC'56(&#/%:+$47!60:C*9%4&"8D"A<C80%>7<7611DC&41(+",1HG4*A=%C137+'".?%=$)2%1+8/>%!4!!+4;/)24>:(H7",>=F"&$';9,'+CD;+$F
@r8348
GGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTAC
+
9")./$(931B.548*:E'2"&2!2?$>'?:DF:G1H07@<H59D'/.G.+C;7'6*BC>?&9'=(/G1
@r8349
TAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATNAACCTGTCTGT
+
$A1799#E&7.'H0->/1:E,;"@12*$E9/+-$A0(H@21D/5#G'38&=F+B/&%C2$?EH:58@:*<C44)E954;(FF/C(B%3.7FF
@r8350
GNNAGNNANGAAGTCCGTGAAGACGGAAATCAGTTTCTTGTTGTTCGCCATCCTGGG
+
%"%!&&"()+$%"($"!+*%%+%'!!*#"'"(+%&#)$((&&!%*%*"+'$(*(($+
@r8351
TGCATTCATTCAGTGTTTNCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCNGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTG
+
>-".)/;(<H?'?4'$+6(6//;*G&0/+-/=(B$?$+;2F+590?5%=D1:/82H+>!GA7<$';4,("!>)8!AGF%87<7*,8%.;5@BF"*:(;8)68;F5@46=*:#@"H(;'3>G;35+$+<,;8'(C@9>C*56!2/B$@B/@3B.,+H6H?=<;/G!9--DC35*;9:$@C".B>#?)C=4?2>9CH7?>.E@C@F3>)4+?G.#395HD938$3:!F0(A3?G7G"6050*-5($GFB%<B
@r8352
CAGATAGCACATGCAGACGTAACCAATANTCGAAATGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTGCTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCT
+
1)6;G'.+=/%'7BD%:,2F?.&1+)'9+"?'1&/=64%?:1@)%H!C?4C7<=-43/.1#>8,D0(;#B%*/B=634%C.,+C9'8BED$/7042C2+8>2E9*9<3.;,'!B-9&4=,2?9?"5"F*@'0B;1E>82@3F6+B"@'&9!0H%;#,2
@r8353
GGCCNTTNNNNGTTACGGCCGTACTGGTNCGAAGATGGATGCCTTTGGCTGTACCANCCNGGGGCAGGC
+
)$'$!(*)!"()')***("())'")%"#%'&+*(!%+$#&)"&'''(!+"(#)!"''*'**#!#(&$$!
@r8354
NGAATTATGAAGNATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGA
+
#3;(/(*1C92"2$'>03F$!!/A@F;)'-%:@-/!3+#.<A(>),0DFE&3!3$:
@r8355
ATTATTNAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGNTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGNACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCAT
+
#/*A,3,;B##!%@18CHD702A;C1H471GAC4G))%>-+#1')2<4%2F%7*88("6.2..+311</!=-%!!>".&!9"&/+&&B)G"#$$87B2A#HCD6-&>A=?54EF&<@=%,"E*;&%/">?6/:0HH=9,HG0!-1B!C$D"0E14G5EG1?G;0:=90!=4?2A6&<&C$(F;#BD@,).-B@65?(08(--:EH1.B*5/,$*00$66G":4C5C:24:'6B>/EE!G6CC+<'77:-0>6<6!>3"::31BF+A62%%8069=9.6=$.+9HAG=:!%2-39"?*-@",=<-796/7/GD-$&7<AF-C03D;(-009C;A=%<9-54%<%$AC4>14B59!)B2*8/9>>>E'-?E5.F+A#5
@r8356
CAGCGGAAGCACCNCTATCAGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGNGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGC
+
?<?D</B+98E!(:(4%;-/G*83!+"HDCE23=*.148!+6,8=?27!1>2D3#>,0;*!B73#)A;:&5'H#H&&,;7(!6')6GA>6@?')F&)&)F($)H8)7E+>788,*#(
@r8357
GCTGCGGTAAGTCGCATAAAAACCATTCTTCATGANTCAATCCATTTACTATGTTATGTTC
+
8G?@<#+41>?/9:H>6GBAH9D=>40=G01/:C>@BF$>*5D"8EG9@B1>(&$FH9H3B
@r8358
ACAGCGACGAAGTATCACCGACATAANCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTNAACTNCACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGANTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGNTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGANGACGATGTAAAAACGATGAATGCCGGGNATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTG
+
0F1(&D*@&7#&"$D=)4F():0?G(,",!0@GC<0)1(!$715/%&),G8"+@3BF&@H(4B;<=+B:E.-&/0G5*E5"$)++,D.G<(D5&D&!D'%"+3C'$=/8+<)?!)@!.%B"<6<051!;+/F(="%7F35A">!+:@D<4%<F83:72AGC%530+5B@"D5*1$5$F06G4,?!B'H/0$!-,",<39+><3,>)6!#94@>C5((%<*BG/8D$!BB48H(7@,6)A3>H3A/#0/G74BE=4>+>GC*E:DD/?>(%H4@1?)3/%)>%43$(5<)1:F;2G#C69<#8@(;A';7)#3/6(;%,G:7@>"D5000+-<,-,6#?,D"5&'2<+&#G!#1273!B/-%982%#4':<+&A.G3/44-/E:G3,:7C?64<C7BC>+=26=D;+91!#D95F6>=
@r8359
ACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGT
+
3;,2E$&((8E,7#$E=%=+'7H#1(6#<*(-+&C'!5)7@H<6,(CED$*$D4C'(.A"-7*C<,<%;)1$2,>>=<$G>4@D<6*,<6=C<,9/'(9",53589-45;F.19E5/%G;F@=-H6'2.;B.A9#>4?0;G8&C#@8GG!E:2HCG@
@r8360
ATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGNTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGNGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAG
+
?-4+%::4*;778/B0>8+)C,7<(2>+8E8")?4@3;3#B@(-A6=G:6("6C"@@04#-B=7F3/2:'G3*H4G$8;>9/3:.?F8+025)#%6?8)7E<=&&H>=F=:@4+50+8),+CFE;29$8F04H42&0"/.6D:/BG!771#?'1(
@r8361
TTGCAATTTCCAGATCTGCAGCATCCTGANGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCT
+
:2;BA%!%&)0*%D"3*+'*F?8G>HHG"#/B;'$<E@G=E/!H0):BB*.-,F$7::&DD?/*94'
@r8362
ATAACCGTCCTTTNAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTC
+
?)C7@:"&:*/%57CH5/,-8C6*8%DC"+F@:AC,./AE&7+?E)11"%-!.'?,+/91
@r8363
ACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCT
+
AA#59D?,E642**)"F-F#08,;)D=;;7D?"383:=%A+(F9#?C+(12A!$=>F$!=DF#(3/*2C@252C
@r8364
ACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACNG
+
9&9D-45/A)?!8#40?1-5:"D71000/*1#'0;3HF3H0!/+
@r8365
TCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCG
+
((-&!6A$:?15!)""-!C?,5(07,-!40=88%8D7'A&C#+109D;5G)-&4>'8/%,7:;!4E><-G<H4$0DD4-'B29
@r8366
TACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTNCTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATATTAATCAAAAATGTATTTCATGGAGAATAGTTAGAGNAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTANAAGCAATNGGCGGTGATGTAAACACTATGAACAATTGAGNCATAGAACTTCCATTATTCTCCTGAAGATAATAATCG
+
;.$)F@$">@@4B>D-&7=F1GA-BBB"EDH:3,H,";<-15()6=A2&!*9?C(A0-FH,-1=(@@4;)HC'2)/5),&=)7:95=G/**/8.A5E"3#1F1,2,"*10%AD=;/>"@B3#2G/!@?:9%G*-D?"A/='0%F6H1>FH%@#G.*!,>0>!4/#+&&5(D34=H3,!?44F>8#F;0>0"0/%!);9,'8+5$A(E=1B<@8/3$$$8ACCG8(/C3/G5CFE3&7C#8004;3#C+H-;A8"#8@C/.'2-$!)%006FE1)3?5BB9BG844(84./1/7;<,H:A@@(?'3/!',:7$2F(FGEF"(?*,!G@0"*&8!"3:./4)#$"3F@-8A1,1<G)AC;;!8;65!4E90,D7;2"#,#!C<D67<""-E/15?0)9
@r8367
CTTCAGGTAATTGGAATTGATTCAAATAATAATCNAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAAGATCNACAGCAGACTCAAAACATGACGAAAAACCATATTTCATGCGTTCAGTCTTAAAAGCAATNGGCGGTGATGTNAACACTATGAACAATTGAGTCATAGTACTTCCATTATTCTCCTGAAG
+
;*#7F=4C76/F635@@5$83H$@C#8$?C%<$AG:$@86B<B7-(F('A>9$0;$66<<:HA!<0<+=%C2+/"D%7@6D>>1G,C5FAH)&!E#8(<&/5%4?&@1E,A8$$3+7"')3=C*(&/&C$.7/";"8.6/H$F+H.>)229;*/:;9><*8'!CAH<</AH'1#8<;'4#E3+F9&8G53G(+#0CFB@B&4'/.D6<D1>F45A)H.
@r8368
TCTGCGGGAACGTGTTCGACNGTGAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGAACCNANTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGNCACCGCTTTTACAGTACCCANTATTTTCATGATGTTCTGCTGGATATNCACTTTTCCGGGCTGACATACACCGTGCTCAGCCTGTTTTTCAGCGATNCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGANGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGAC
+
D6;74#:)C?<+;;#=4"G20;#:46//<(--:G>,#A>40!%G-;C%,!?%:C2'&259;@BAE*E40;&*28?<33'7'E8<?83"@<4%;745-@!'*/B0*<7#39C&:%6;0&A<$$4>#>B/3(C=!D7@E1;:!):/4F!/=/,8$='?#B$5B&:2D%,D#2=4&>.,@0C1?GB46B0/4/(8$:5,8/G$C#BF(HGE9E>6=5!=F<4,?;,@/B1EH?8:1#9G9:C6)<2'."H$,$(6'?*()1)BB,5(@E<A%$/6B>D-7##A7D$5.B,>=)B#%@&;*E9$0B!+!A<"++C$C4<A$+D6H;FG19@('="(('B);DG:E;>>)A'=*1C8A26)&+B$&9*)-35..9?FB/'.H98/&%0&D?E*99,D@(#%0;272)!6"D
@r8369
NGTCCNNACTGANGAGNTGCGGGNNCNGCGGCGTGGAGACACGCTGACCATCGNTGAGGAAAAT
+
%&(('$')(!)#")&($%%*"'#"%$''+!!+&%&)%&!$'*$)*"(*$$(#!*+#"()'")#!
@r8370
TCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATG
+
H45A/9(;'CG%="+A4(.1/1A&,9G#HG>>085&6:(H*%&!9C14@*$;&>=$-;.=;32'+@%GC4=
@r8371
GNNTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGNCTTCATTTGGATATCAGAGCTATGGCTCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATCCAAATAA
+
('$2*26+,(G9$-5E2"6(6(G*@'3",>65./,!C*,"*$82C15&0C8":'"(6A"1'&4B3(C0A5&%&'CE083"7&;&H?G)(D<)3>A/(1@/*8CA2;*@$+3@"63<G#60#68(=>*!@69D<%"/=#&H3.)1="<67A+0"0C,G-%/.24A1:%B$44D5("'>-G=@88C":;<-4H9!@#>"%A/!?/!/<'1"@F/.32B/.=#<:@-3@$C7&#:)C423(EH740C'(;*-"::86B5:1!
@r8372
NCNNGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGNAGCATTTTGGAATAA
+
)*)"('!%#*(%))+*)#(%&"$"&(#"'$#'"$(!%"")$#+$++&+&!*#"!%"(&&&$%!)''&"($"
@r8373
TATCTGAACTCGCTACGGCGGGTTTTGCTTTATGGAGATGAT
+
G?0=4.'=/@@:@HA:<#!(6$2'",%B8)/<."1H=:DF8>
@r8374
GTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGATCTGCTTACTGATTT
+
),5F1$7>+;94G!0@D,=(;F-!A9G4"$*/>2#H$EAE7%'$<4!HC@E#4'!%@&(<HA*A:4/
@r8375
ATNTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGCACCACGTCAGTAACGTCAGCCTGNGAAGCAGTGGCTGAAACAGTTGTTNATTGAGT
+
0.:8@*7+;A2$G55(;;@$#&,&AC?'567)':$'2#)&A"4'7"7@2A@G$<4G7?*B0C=C=(!>F)57A3*F-!B,DH>9??-2$/6D87;.:3F?"$0./<+"$9'!3
@r8376
ATACAGCCAAGCTTGCAGAAACGACTTNTTTAAAGGACGGTTATCACATTCAAACATTAATTTT
+
5,(/HA"#E=!!<(;%5":A.C5;3DD<0'.&D-+(72+-C+A>AD5!2,<F5BB7#5(C,5-F
@r8377
NANNNNTCANNNNGTCCATCATNANAANANNTCNATGCNCTNAACNNNCACNACCT
+
"#!!!!#!!!#"!!$#"$#$!$!#!$!"##!$!#$$#"""$$!$#!!!#$!"$#$#
@r8378
GGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAAGACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTG
+
%G58C3DC=/+!#5"B(D5(HGH;GF2"G912=G'9=%,<B#:3FE/73>*9.:<!#E"(G/<*E)FF!92.CCE*85/<G)6C1/+E:"GC"634>*H>#8/%'+3-@-AH""*@39/%F0/$1'C9+@(2!(6-91=?F+(B&<.<$E*/C?7':F*DG'0B-9G%%<A,3G(4?.7@#.#<4C<*:>8G3!3
@r8379
GCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTNATAGTGGCCTTTAT
+
D+@H?+DE?6$-3$G/9%D+)@.(F?B2"..4)8<+,#GC<?07C%-&?:,360A6-C/;$
@r8380
TTTACGCCTGTTTTGCTTNGCTCGACATAAAGATATCCATCTA
+
-34=D,A6("0@=5732/&7CBD*28?6$$=C0?,$3F#+669
@r8381
GTGTCTGTNNNGCNCTCGTTNCCGNCTTATCCTCTNATACNTGTTGAGCAAACTTATCGCTTATCTGCTTCTCATTGAGTCTTGCAGACAAACNGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGNAAAGACCTGATGCTTTTCGTGCGCGCATAAA
+
**!&(#"'#$#')!&''$*%$)*&%*&)&!##$*#!"#)$+#!%%'$*'!"'!!#'#!*#'*#'$$+"+*+%+#)#'*#$*&")$(+&+$&$'")(''%(%$))))#&(#&%%($%##"$)#%'#'(*))&$&%$'(*')"'&**&))+"#&''("!&*"))#
@r8382
TATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGNCTGCTCACCGGATG
+
D?963+>*"*9;&,:B>$:$;-:!G.D;)B2)#6%*@&9!F:9/4(A;,:>H'/&&2
@r8383
GCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAAT
+
/2"1E7--1!!768<H:.#<"&:2#$9#3$+1:&2?DG$H=;$+D82CE:3=:865#.00A(2-F7AGA2$*<@?=F@348=H1#H!1
@r8384
AACAGGTAGCTCGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTNTTTGGTGGTTCCCCNCATCAGTGGCTCTATCT
+
##+%%%&&#"&!#'+!&'#)$(*'")"*&!(+($!"*#$*#%))#"$*!%))*"*"(''(!$$'!*!#&*&!)&&$"))$&!'%"'!'#)%+&'"!%'
@r8385
TTCCAGACATGCTCGTTGAAGCATACCGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTG
+
3/*F&=(53<2G/CCC"7'15+)*-D)7*8E-=)G.6/C4GB$B$E>8>CF639!2C&95#>;)DB#$F)?<.!/?)G-F$AD(83H52=
@r8386
CTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTT
+
25-C,%G:/&9?&,268+6G*<G0C062$$>A1<D7?"2"1*$B*@'C6H+CA?05!6G
@r8387
TCACNGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAA
+
1,>?C<6@FD"<"90%G/45"$?E1E#G!GGG.B7E;>8=/G*
@r8388
AGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTGAGTA
+
-?A@>+B"<.@*-6&";$3"62@#</>7E"@0+E&(#=2!/E8HHE%=)-G)2@11!#::2"
@r8389
AGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCNGGATGGCGGNAGATATGCAGAGTNTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGNCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTT
+
F4@2%GE74C)D(*?AD4"B8">-<H!91%>C,B7)2#72BF(=?9B:<G6268.13.6E2H9/D142)*,ED7)=7:4686$4@C#04#(9G'/2(!CHF"(2(=F%;A@HG3$F</2,$=<(7=>G2@9?:-%A97A9@C3/G4BC07<5;/);BHE./5$"AE?26;?'"2"F4@B+<9/2B3&-;!2GF)5#E/476!7/'(8!-'6?20$=767%6,.*<)4E204,.(-%>55C%)>7,0FD/<27>@$7A2"@<5!6-48
@r8390
NGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTAATATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTNATGGCCTCCACGCACNTTGT
+
"2!%1<!#!85)$&=108,5;>,9H$%=,.5">)$":=">!,EDHC3DHA)>$.B1!67/5?.?&/G?(5*+#AC%(.3<7!:H#H83*&6!EH2D3:!0F'7.-9%#A2DG%(6%-;,B3AF9BE&<,"!EG<5,'FE#%9+$
@r8391
TTCCGATATCGCATTTTTCACCATGNTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGACTGNCTTATTTTTTTCTACTGCAGGAATATAC
+
?FF;C&%&03@B2F13&*;453GA+049C@1#-6$F)9),C#("3!:/*7;4'4'EC;<A./@)C7?%923=8(2:;5.6A@;A7B=?!;11D+<51'G$2,$?H4/6*<F0D:==.;:D$H8)!
@r8392
TTGCTATCTCCTTTTCCGCCACTACANTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCA
+
1:.,)(9*2=@'%"%8H83*E:#HB.-<)!0/"@';!*B<7/(""F#>E>,/65"%;()3H<<#-&%7%;*A#*3BE2A
@r8393
GTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACNGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGNTTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGC
+
/G=/B:<B1)9$*"D0E3(?&+E"E!?<.%&4@=.-:+!>5&E#D<&@>6="..($0>G-=?6A4%1@@1&&2;@1?%2:?C.9$&D;C)G$8$+.A$.:*E:!-&.<"89*7H,*$C4"*9(68=B3.D)*D%H)"0<#<<!$1'9,;0*)$/<7??G",C"B>8C+:)@.*7"3"(*%GD1>4>>C7D>?+02"D:%..)(BEE&.?8C04(79FD77#/?.46
@r8394
CNNGNNGNNGNNTNAATCAANCNNCNNNNNAACTNNNGGNTNGNTNNNCANN
+
$"$$!!#"!!$$$""!"$"!##!###$$!!!"$"#!!$$"#$!!""#"!#!!
@r8395
TGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTT
+
*=;G.8F>9<.G.="C04>"$!;H'$%'EH"7.57H!/**4;6$G$A=!9>,"((,'A%@7:*60G30AFBG+;3?7AB@
@r8396
CGCTTTATTACCATCCTCANTTGATGCTGCAGCGCATAGCNC
+
?+/AFG%!4D)*,=<&50!8*+!',:?"/G.-,.F@BC/;<C
@r8397
GGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTC
+
DH$H=HB0(3D6$H/A4=BF>(.60,H50@<E)@F<(F2/.;+(3:<7?<#,,)&E6./=0:12!G<0@@,%11
@r8398
NATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGNTGCAGATCAATTAATACGATACCTGCGTCATNATTGATTATTTGACGTGGTTTGATGGCCTCCTCGCACGTTGTGATATGTAGAT
+
"!+"#&+%)$!&("(+#%($"+#)&)(%)(+%*+!%'"+%&$&#&%$"'#%!+"(""+'$(*"&&*&*!'#*"")&)')#&(*(+*)#"#$('!))")%"*+(($'"$!+&"##))"+%#'$*
@r8399
CCTATCTTTTAACCACATCAGGCTCGGTGGTTCCCGTGTACCCCTACAGCGAGAAATCG
+
,"FA8#395C8G=(F4-4FD*<)@+.4F&$1.<?9>H4:;EACA50-HB,*F(-7$)5<
@r8400
AGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTAC
+
/*-8+&(8*D*/63@A5:8<;%AGG@(4=.?(<#1=4-&3!79<+<6F/<8"?@H"594BA%(9<.068*B@-7G)9(5<C69)@)C#-;,+H=%.?A>2G6#$,17<E=!)(4
@r8401
TAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGC
+
BD8D7;G=C*3@##-3!13HG:>G#BE2);:/+'38<;GG5,@)D@*)8
@r8402
CGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATG
+
92=4:30=A77$)G'=2=;*%1-$E%5<"6=G'%("$)+9&&)F1%-6:&*"A(:?@,'F8$?
@r8403
GACCTGGATACGCAGTCAGCGATGGATTTTANTCTGGGCGC
+
;?,35B!%(8>0";$$',#-+GBHC>D2A:?#2/9)E8D/F
@r8404
GCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGANTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCNGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCNTCCGTCATGTCCGCCACATCCGGGG
+
'<G>17?9A.D>69'/#(76E@5F/>3A&>;@D$)/6=<D2H<4579)E+*.:="C+G8;.F-2B+=!C>C?('(;!@>9)B*16D9/6%G(9!6B&2HG#F!FC>/2$%>71=/D8H8(-A<7/4*!%>,%(%&3H"G3'4D7"B"*!8;69",<7B<?/.72/G*!(9B+"(8=-@%*6%!5&$CF34B:-2AA@)F0")GAD:2**!9;$A#G03:30?G?G?A-+GB&@$=%3A+)@GA18F$FEF9/.8<H/>HE+9G3,3H=5$.@+'E;(&0-$.76-G#D-$!19#(-@()1%>48DF<&2$F)%7&/@/'#920H.3&9#C7@.
@r8405
GCGTTCCGGTCAGTGCCGGAGTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCA
+
(,4G:("4*E<&;%/D4=&E65?#-$27,!C:)$$#,*A?4%.3,=E&8*=-,3"4B(6;5,?+9F#02HB/,.;"8D1:&&
@r8406
CGCTGNATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGANGAACGCTGCCCCTTTNTACGACGCCTGCGGCGCGAAACGACAACCCGCGCATTACNCAGCTTGATTACGGGCAAATCCCCCCGGTTANCTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAACCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTT
+
*'$'$!%+"+'*#"$*()*$*'('&!"+!$"'**!&'')++$%+!!$($"%*#&+)(%&"!%*##'%*"'&%*+%+%(%(#&$#+#'"(!(#*""*!'))*"!&"'("'+%!(#!(+#!&#&)+("+$#*"''%%%%"+$*!*#$((")*($*!!**&)(&!)$$)"!')(!(#''()"")'&%&$)%%$$!!"+#'#+$!)"')!((%")"$""%&)#'&(%%+'&#!))+$))*!)"&#*("(')!+#$!"%%%$%*%)'!$#+(*+''
@r8407
CNCCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTT
+
''+#**("')'#+&+'!%&!)+!))('(%!)%#)*"#!*((#+'%%$+("$*&)!&'%'$($"*'+&*)#'&)#%!&)'%$+%%'$($$!$+(&"(*%$+!#!%"*"#+*%)#&*'$&!%!"&$#(&*%$(%#!($())'$
@r8408
ATCAGTTCTGCNCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTNCTTGTTCGTAACTTCGATTTTGGACAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTA
+
%*6E;>:BDA.5->>.+DC-&41C9=8?,#!C+/30#9-5!"76"%8@*4":?127$6;4%7"!&A:79%;C08%;A<54/.,'*E:>19<;<,H+6AE/(-$@#'("B4A>C-+0$/0?-.-8FH"HHC(;11-9'=>9.%3G1(E0F,8&'>:>A.&D5-(?=493=-&<%"8+=*H"-
@r8409
CATGATGACAGAAATTCTGCTTAAGCCGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATT
+
-@=A%'7,+<&'BF7@5F0-!;C<1!!7'<)9:@":=,'=6&;,2.29+.2&72-1#(-(B.),F?@
@r8410
CTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATNAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCACCTGCGATCCCTTCTGATACTGNCATCAGCATTACGTCATCC
+
3#4><92>/6<'35;'&B-82E6=E)(.%E13G009@H$'D1?.+#;!%.F"81FA>*9A?99#+#E*4%-+--F9*84G86&HEFEF=@>)BH8G9%<5A.CF7;'E7)+,GD7,9C.#C@D:==0
@r8411
CAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTG
+
?6G;H>#,'/.5+;&BB,@1)59C$(";&DDH6'<'-:!69"*/G$?$B6B4E"5@D(E$98CBG(DH!42
@r8412
ACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAG
+
/&6?1+C41(>64@"!%H/4=4!A+*5D33B1%;C-'(G:GF(F#B5("$.('-93>2/=F!/(;
@r8413
GCGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGG
+
73+1#:A2++!=#B(0!?:506':>,(!5563:35'&#F>#32!(:+9@&-(
@r8414
TTCAAGAACAGCAAGCAGCATTGAGAACTTNGGAATCCAGTCCCTCTTNCACCTGCTGATCTGCGAC
+
362+6$/.;'$<@,A:HFB*6!$6<A#H%G!'>H,3*8/&2>(H=+00F*@8",&*$%D4<%3:$,&
@r8415
TCCNAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCT
+
:0C@<C283@((H"57E<8'4;>0"*:4?9/(C"9-6FA15:C6D%B?%E3,?!;93E6!A3A)<E&-9*<<!F!("*2.+.),(B)'G*>#C$05/D(=<9CFF+58DE/@E+B1-=:;.;!1,3>ECC/0>.'>;(.H
@r8416
TTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTAGCAGTACCTTTGCCTTAGTNTTTCCTTCAAGCTTTGCCACACCACGGTATTTCCCCGATA
+
('+"$!##+*+($"$#&&*$&%#&!)!)#)&)*"(()*)''($)*)$$%!%+)"$%&(&!#+%'&!!!"('!+$"%(%%$*%*$(*!#&+!+"!#'(#$+!$#!)&'%$$)'"*+%(*+(
@r8417
TACCCCATTGATGTGGTGAAAATCCCGATGGCGGNGCCTCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACG
+
GH591*3A:?'!=F?0(,D8E>G=7<:)!D"<026*?88)F4BF80C=#%89F"+$>;$G'752;H08C)(FG4C$=C=*D"@#,G
@r8418
GCCTGATGGCGCNGTAATTCATATTGTTCCCAGAGTCGCCG
+
(?H:$6%4#3)D!5F#>5'3<5)-;)G6.&H8>7')4B20G
@r8419
TGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTT
+
:;=?#$,");"6!HG2$?0>,+"G)"=9<3DH+<<@619/>".*-5G8:"5AE=FF9*
@r8420
TCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGNCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACA
+
.+:D.#D9=GB@.%B;::5'@>5$0/;F+E6%E6.7GFB-(%'/)92/G>A88%C.;6#9(97)A>4!/&%(58'-!C.#8<+*1*D.'G?4%(E@#<G63-.83-#&D<&B+04579=@;+4,DB4+2B8C<8#191:=0822&!F7CHG,3!/6433.-=8@$D665$"856H,>63-C"43D7-3,=+H"*7+6;E44.>3&?0/!66-/=(DA!H2A#'A73#;G*/C$;<&0C"5;67>
@r8421
NNCCNTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGNGCCGGATGAAAGCGGTTCGCGACGAGTAGATG
+
'%#)#+&"$(*+*('#"()#%$)$(!*"!"''++*&&'$!$)#$%*%'"&""'*!'$$*&%*%*)'"%$%&&&%'$)#+#+!#*#(()"&"
@r8422
TTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTC
+
AH?9&G)$#38))$B+&87=5!*DH3E%,1!!6:G30;);-#;$0?B)D*
@r8423
TCCTAATCAGCCNGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGA
+
G8?D*34(>,<B=+C=$(3A*:D:69&@)"4;!,%G-2-D&@'E,F+7'10
@r8424
TTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATANTATCCTTGGC
+
)#<E%@?2<!8E9/A5$$--'@B3?*<G#D7D/:B-=%-C8!8'<;*@1?><&*9B5:G$3*FAC(.*:2B.)3,H>3"H0F-0;F;0G%#CC3EA5-,)@1,/B!!79'-1#H#)1G1A:,"/9/9HA#2
@r8425
CAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCANGCGTATTAACCAACNGTTCAGGGATTAATGAAAGATGGCAGACACCATTGATTCNGCACCAGAAATAGAAGAATTACAGCGACNCAGCAATAAAAATGCGCCGCCTGA
+
AB">/8"=!,!@$F"'1F>3"B*9(2<416!@/<85;)F@46,,#@*,:B>56*&(1("%,3C-(DF+$8,+>,/#--7,(-FF>*.'$&"B*G+G&.6.00:F/>:)4%GB621)*H84;;D6A02"@5$A55+A;;+23G&/7;:<#B-47
@r8426
GTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAA
+
6+%!H34!*"+4,G)*2B/C7G58'1397@3>+0!&93F!&B
@r8427
TGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGG
+
+")&&$%"'$&)$'*#+%)%)+&$")+*(*##)$*)'+&+(!)*$+%%##(%%!"$*'%%$$#
@r8428
ATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTT
+
43D6%(!%63&=/9/*'56CHA6!-CBF8(*A>>19:HA;0B<%,D!3&<+%E/:1@
@r8429
GCGAGTAGCAATCTCGCTTTTATAACGAGCGTGTTTANCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTNCTAAAAAAGCCGGAGTAG
+
#'+$"+&#&$!($"%!()+('(%**'"&$%%*)(#'$*&+%"&++%$(('+$!'$!('$''&&("!$!$!&*&(+'$&"*)(&&)!&)*%+*+++$"&)(+$+*#%
@r8430
TATTCGGGAAGTGAACGGCACNGGGAAGCGGTTCATCCCCTTCCGGCGTCANTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTA
+
9C'@G%,H#HD<%CE5;"3=6H7*,F"7)32B6GAF$GE;B!6H*0G2?D&)4"D"-A;=%1+"9?%9=A995.0*3(#264;9H3>G*/;=
@r8431
CGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGG
+
4#0F@HE)CBDB>7E32(-!=08-><:(@'#=')$:6<@F;"&&H$80229+"8-A&F#943:-85&(3@88B2H8":(HG)>2AC'CB8&4$:40@1F8@.6$8.
@r8432
CTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCA
+
13'B68-1DB@:<';201)(H2,69H5@#0G#4683$?3;9*-F;G63G4+
@r8433
CTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAA
+
'07$G!+6(,*2:=!?"F/&G%G4?B>,F((2/#;!0(CF+:2&4=4
@r8434
GAATNCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGT
+
;=*2@CG=F52$3-955'64AG8<&?614"C8#H;%$A#=B!:";:%@C5>>&(:#'?)=$D5!'&9//)A;6FA(%8(#<#G-701C58//-HB&8<H?DH#)E/G&HG/E";><2#(F/F'.F-//,>B<-.<C4C;!<;C)?B"/0$H*(F::,(*%C!DDG%H1$'<6#6E(3!(AD6).B-=1=2"C!$1;!E$8H5)4AA@4"A#@*=,'4?&#'G290'6FD,5'',H/&(>"7/
@r8435
GCAAANATCANNACCGTCGGTNGTGCCATCCCACGCAACCAGCTTACGGCTGGAG
+
''"$%$!%(%#!#$#$('*&*"*&(!(&)+)!*"%$%+$!'%+%$*"%$&*'*((
@r8436
GGTATGGGANTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACT
+
+%"+"#)$!!'%*&(%!#)&+#+#"%'('&%#$+(##&%""!($"&%!((%(&'*%$"!(!$$+("++&)*)+&+%$('#&'$%%"&%*!'&#*)'*$
@r8437
GAAACCATCACCCATCATTTCTTNGTTTCTGGAATTGGGCAGA
+
A?#/;&5<08(*E8:6*BF+6G!A$B&6'<91"315?DGC%%=
@r8438
GGGCGGGCCGTTTTCNCGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTNAGCCTCCTCACTGTTGAGGAT
+
"H$&506D"B8%&H<D"8&B"913C.F3"!#@*+,;??97#'D9!+#.+H#A#:$$13.H*H';0*)#,F'C5BA>5H%C1?=.0BAEB
@r8439
GCCATATAACAACAAACCANGNCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGNCTGACGAATACCTGAAAAT
+
&3!806-A5"%5FH%/#/*+#B*0?H8&.A&=B%BG*<@<0<E+HA@7A>=9>#=.*88B5:,#/.-<%D-E??AGC1&=E5H3!%FBH/"
@r8440
CCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCNTTCGGG
+
2.AC40;78@.C18*H&G0,<@54@H*9>A-%$&@*#;+%:8GEA369A:322CF$
@r8441
TATGCNGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGGTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATC
+
&"$''#+'$&*$&!(%*&)$(#%$%#'$!()+#"+)"$$&*%$*"!!$$+"'$)+$'!(#'$%*$%!%"*($"'*#+*$$)$)**'(('*%'*!'"!&#!#&"
@r8442
CGGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGNTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAA
+
($;3>>GC/9"/!58(%<=">F);.25H1/!$B:!G"#.7;<D9E6>6?)ADH:F(?*GF(BD"HE%B**E05*B"?5!3@1<8AGG-$GD>:D.:%:$?,=8+AF?6<%%%&6DD*-<$$:<)90AG>B;77D-AC!A55%'%>%@?..$G:$?E8G-7#G8<.9-=.8&+49>>=?2
@r8443
TGGGATATACCGCTCACCGTATTGCAGGTTGATATCAANCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATTGCACTCCATACGTCGGCGGCGCGTTCTGCACTG
+
&*+$%)$$'#&*#!$$'!((%+#)!"*$%$')#!&')#)#"$%*+&'$*&+%'!%'"%%#&)!!&$%%("(#())'&(("'&(%#((')"%+$)*'*&&&#*)$+""'#')!&+"$&*"(*!)*%&&''$$%%)"%!((+##))&!'$%%)(%(&#(*(#"))%&&!%(('+)+&
@r8444
CCTGNCAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGG
+
'#%%+*"&!#+!"&+(#!!%"'$*))!)!&&#!*%*(&%&'$#$(+)*(!'##!+*#*%&'$"+#*!$!("()'""*"
@r8445
AAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAG
+
/1=78.?FC>9B;C+DD0DC8<A>"B1>67"@BD"F8=(11&!?6!2&'F6GC"F<.&5"-F21
@r8446
GNCGCAGAAGCGGCATCAGCANAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGCGTCCTC
+
##(#+*"'))'+#'($)#'*)$'$"*$%$%)"**&)"%!!%"'($*("*""))!!*(#)*("&&!
@r8447
ACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAG
+
>-3'.02!C+FB$5=60E2/A,AE+9%9/)F::/C80:-)(A;$53:F*C!$'1"&-)?<"-,D-BGD"(;8+()CF#/*C%!>5:%=>
@r8448
ATCAAGCCATGAATGTAACGTAANGGAATTATCACTGTTGATTCTCGCTGTCA
+
-G&CF14"!#!?'A%@=>9/;ED@>#4#-C,F'<(<D1FF9:*GH-6G(7G(1
@r8449
GCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTNTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCA
+
!B9!13'ED3C(>).55A%F@#.;*A7&/>1"2H$&B.!123@GF!(9!4-0/A6!+1&8C@CD/%"/*1A#F?G:C"5.(9?B)97&/&;EBB=3"F(+G/;!4(6%A2'8:>0:-<#!+B%<A0+<+<'5B'2!,?=G2;8<>2<%95?;((H/,H"!G-=.#41@,*5$$*9=D$71/B-)F*;-?#=!,4"4F+
@r8450
AGGCGGTACGCATNCTTTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTNGTACTGTTTTCCNCAGGC
+
@:)$G67/3/7$.66G?A3=H$FF:4+7)A-%0&;0:+)7<7F&?1'492A59B#;',"%E)-2?AE)./3:*>3;>6259-.5+!)F$<C0?"+(B*F*991F5?=AC).=
@r8451
TNGTTTCAATCTGGTCTGACCTCCTTGTNTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTNCACTTAATAGTATTGGTTGCGTAACAANGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGA
+
(!''&+)&%+*""))*)#*"'))%$#$""'+'(*%*"'"(+&*("*)(&"&#'(#*!(!)'+#"&%**$%&#()*!%)""#"&&#"+&"!'+)+'(+#'&#"'%#&")(#%%')"+(%&$"%(#+"%**"$%!!"+&"
@r8452
GCCAACACGCAGTNTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTANTGCAATGCCCTCGTAATTAAG
+
'2D/04G8F.3@D20@871:03)1$E(7!="A).E7'$(?D/':A$83)+@FC*B>';354C=3?F@<,,7<&3,
@r8453
GTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCC
+
4H@,#1=,B:0G)$',)-97,=@H/?&31"-E-D?F9<656,(9+GF?A7GF#<23G"C7>D%&8E/!<(E%;?@?>(!*:3,"1<1%088G/.19'"*
@r8454
GGCGATGAAAAGATGTNTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCAT
+
&+"+*'"$%#+$!&$(&*+)&"$'#"!&&*%!$$)*"#&&+()&%)"(!#$+$+)&"&*(#')##&"$'$$*+#+"+'$)(&+
@r8455
ACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACNGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGNAACTAAACAGGAGCCGACTTGTTCTGATTA
+
&7(<'>9#+/5=('/A)G2**G(-#!E9==6:9459GH(EFD64F;B&8D!?@84E:%-?:<?/@3-=!*>)H2E)-&,:2,<+;6DH5,"EH?6;G7B"5'>AG/FB%DA65;;?F0&;5A2=@"G2$651:,+4?0
@r8456
NNGNGNNCANATNGNTNGNNNNNNGCNTAATGNANNNNGNNNNCNTNCCTNNNNNCCANNANAGNN
+
!#"#$!!$$!$$!"$#!$!"$!!$!$"#$$#"#!"$"###"#!$!##!$!!""!$#"!"!$#!$!#
@r8457
GAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTT
+
#4<.7/-:FA;"@9;.&G8(*+A/<0A;;HF4A9=.*4H5&/F@*%$&,&>;C7:5;=A.C7@H3$;9'20!(HCCD<=>(?*(;27G!=4A463$*CG$;38"E
@r8458
CTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCNGNGCG
+
B2+H8!,H)"6"?(5=52;!AFD6(?!B,?>2*429/EE:"(:-!??7(B409=(6HD+$=?F00&=+;140203+>/'.D18>$.:(,*#1G*4%>9E268%//B$2(,'?'-/$6<HD+;G;A*=2-#"+*0H'+G$BG">C+")$>:E3#!"96@-2,?8C"$G16/1
@r8459
GGTNGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGANAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAG
+
,1$;?B$#(1?A88/5!#+!6+C+A>>$*(B9F)&1'83$/D9"9#9-""G1A(>$9;6A*'*G"!&<?<$(1<@F1$/C<@A:>*'098-44$EC>E$9+:/;5!<E@2*$?GEH'<D=&1"B!6C"#F7!7G.H1)F:'+E&>$6$2.C1G7HE2)7FC!&?(;
@r8460
CTGAGAGCGGNNTCGCGTAAGNGTCCCGCTCCCCTTATAAACCCACAGGGTGG
+
"'"$$#%'"$'!)()#&#')('&+)&+$)*++$"%&#*)%%%'%+&&!'!'++
@r8461
CTGTCTGGCTTTTTTTGATTTCAGAATTAGCCCGACGGGCAATGCTGCGAA
+
H,>%/G!<!-"%--$?=<-/;DC#=HA<<BC;AG$C/>+"$C79AH,$,9G
@r8462
AGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATNCAGCCAAAATTT
+
@+:#?+9+H8@.!<)#<D4%2B,H1B96B,'09'?D.<4C-*;@A/"05-&$.A0?G3'74#*B";*,:@;0A1+@'('(
@r8463
TCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACTCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGA
+
G#*")93$7F>&<A&F*/8,+"69@@4+4%E'">>8C,/;5C7$9<$:=E.>&77)3<2H9%=?%*##17#4374$+@'%!0F./"F,8*),90'5+&.>*#>#0@1+%)'G
@r8464
TACCTGACTTGGCCCCGGCGACTNTGGGAACAATATGAATTACAGCGCCATGAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTC
+
'2"0''.3A8@,*<1/BH&A>/<.B.97==FD%/?<07F73&565B%.&G"5B**!6F2=B3?%7DDC6?<"H8!*>/D!E91>-@*-9)8E.3"-"H8)2(6@"+?<F&/$=F?66!#"G#B5%B'B7"*C6,"B.
@r8465
CCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTC
+
);!0.((28C$449E<3=/-*;))F.56$35("//:,:E.2F;@D:!!C0?HE?<1&)<-#B,,23$G>0;A/10?#?<E???#8
@r8466
ACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTT
+
03>"+:0?085.#%3$,@+.H"A/A->>%9:9)$@ED'"";F+H$:'=HA2=DG9AHFG9'(5=,3:
@r8467
CGGCGGTCTGTGGCTCCGGCCTGAACAGTGNGCGAAGCCNGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATAT
+
)))*+$$%!##!+*%#$'%"*#"%*$&$#'"')!"*"$%'&&$#!'%!#!%%!!$&'#*"#!++$(())%()%)##*###&"%%!
@r8468
TCNTTGAGAATTTTNGCAAGCAATGCGGCGTTATAAGCNTTTAATGCAT
+
#("+$'($"!#"#"(!#"*$)!('(!'"#&("$&"#!+"$*')"#"$#)
@r8469
CGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTAC
+
#41)$8(&7%7$&!F30&*E!6B-(?&@9.<5B8G;#?D9?&'$88(5(,##3D=(>A:3E!4<-G>8&H>6-9)."G@E">1A<A1GG*&,-=B23'/%')(,F+G:=<="4&,#(51$,3)%/=)0#>540=!87,(5*70&F*>!<'=/41D4%CE#(C)FAGD@8:)$-;E'B)418@,B>*)4:C3<&GA,287=;F*-*!:*3#&+-H$2/CB'A'F<";>%HH)"5+
@r8470
NAGTTCCATCGTGCCGCGACTGGAATATGGGAGAGAAAGGTCAAG
+
#'*+)#'%+'*"#"('"$((&&(")%$"&(#(*%)#)&%+)%+*!
@r8471
CAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCACATGCCGTCCATGAATGAAGCCGATAAACAG
+
A802'C(."(%1+",A.F&?B-8;%/C5.B%!G69F?G)&(1"<3'F49%=(#!'0:/>28C0'%4@<"5"0$/30,>5/3+<;F;3G;-/
@r8472
CTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTC
+
.3"B"2E</+'-00A-)0A>4@</#E8E-BG*/8(+2)H*<-#8'1G7D;(#
@r8473
TGCTCGATATGGACACGCCCGGCGGNATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAA
+
)@2+5;%63,,5#9F@C2E@"F*'8&=$E1"H"0<D&H)5:(<>FB9618)8/?D<9'D*)""(BB08?H83&4<9D6'&,"#
@r8474
TGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTG
+
5EA"A',)@DEB!/9@;*&78;".H=@E6F4CD(D0=&D3',+5"
@r8475
NCATGTATCCGCGTATCGTTTCATCNGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGCCACAGCGCCTCNCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTGACCAGTGCCA
+
"12?%C41<#<-6@FE@A"(96@*+.+"3!@69.86C!/+7,H=H=/3B'#1!!9F2'1!!*.:&5&%:029&)!E:+A4"(*-7',%0;59$?$2/".C7!4G1=-&3'3/$*.A&0B"!8*>"&<#-#*AAG>?$72'<$2')C6#H$3>-,G2*/+!8)?>#)8D8,DA)3+$F22-8?$6=&*G!686/A;75C///5A<7A.;@<?G>;??"C*3&%&'
@r8476
GACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCG
+
&+(#+"&$**%%)%*(%)%$"()!&+$"%"*(!&(+#*'"$'+&#&##
@r8477
ACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTNCAAACATCGACCGTCTGCGCTTTACCTTCGGTGGACAGGCACTGGTGGAAACCACC
+
@&E2$:533-HB-E:E$3C3?C0E+.E6'E6(#%@*'1$2!<8G";C$,/$*F*563':1B-@6+83D#>HB3FG97:;?E+E2;G:34HDD<!D'C=-G/9G"3*@/,:9%H/
@r8478
NTATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAA
+
"=?*>EF@3B(7.&4'10$":"A%)<B-0!D?5539C?<@$(6/?5+6":<>:>'#<73&245H5?*%"6G&*#A/)'30":0$2!0*1C2@=8=6265F)2'(7FC9:'!4&D1==.H;-(0D#,3&31H'2%H,1?"3+H7*F(:F2%&1!*.?4?&@49=G?-&!#(%2<7$'/64"<)5'
@r8479
NTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGGTGGCCTC
+
!,4*?H<3=8H21H5BF&7A>).F5<F1"H=H&&;8!3#>A"<""',+*,$-E3E;)/;D/?D78$=.B"E,)-"#DC*6<<:*5F8:,H#(0%;&G7FE%'!%@-'%?3AB1@+++":'1)$F0:36-@*G@,!7:%37**83!/6=/F
@r8480
CATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCAGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAAATTTAGCATCCGCCCATTCAACGGNGGTCTGTGGCTCCGG
+
B(69G24$:>*>E1)BCB#(',%1:5ED&H,?51E@#DA<:;$/(1C.HA,F<FC/-2@#/G%50?/<!8'7)"=A=@8(+=D((#H;<8&0(8$#*';-&*A<51+3/0A-1F5!4E2<(9*99774,0(%!&C=2)!2*="!4121FA
@r8481
ATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCCGACTGGCTGATGAACTT
+
<A*5(62>5;;;3F90"?E+4;4=<:$@2FF.,81(,%,9C:98!E).@23)=A;0)./DE(E)A4+14)/DA!C%4$@+:<CFF:,=;C>B10/G!G5*GA526?-2:)5*4A'-,)/F5+91,:C5C/"4?47>:"8HE>?1.0/<&#*=#7;-AA0E0=*/3$6416-'@HH>F24=-G?;($=&B))")&E05FA&
@r8482
TAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGAC
+
#DD*H?"+G?,0$135+&#7#&=F3H66FA-G4H;#,2.%+;
@r8483
GGAATACGACGGTTACCCACCACTAGCACGCTGCCGCCAAC
+
*?B3";3A<.0:95+3&>E#4@@$#3)'-E?G07'5C":5#
@r8484
ATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCNGCGTACTGT
+
7BE5G679D<%9>88G=@B83,02=2!-BD2/3>D?&,7+-H*;*5<D$-BG*#56:?#*4C3)B;,,-F.%&G?-HAC76?3>@8G23':#*?3'/47
@r8485
CTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCAT
+
=H+$!@49<.(><(3<C;-9D+?:D1HH1:*+/7-B$H342)4H>8B*<!-.A.:5=4:/CHE0$057!62'4':4&>6;
@r8486
AGCNGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCA
+
582-4+,.*!BFE=%-0B51?8(7:A58H'EBF)'4="E:-4@;<=D=?'7<)-9;>&EC'H(C9C23-G<E02=>:.-6>.=*6'E(F11.>0C
@r8487
AACCATNNGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCG
+
1A>=6C?%>@08?)%!$=/8;!-:02A(1.<0%*394*34+5C).,6%:(1G-:84B?8*@*$>1;!%!;!4G,%@'9C/DEF'-/)3:)G$6+C#G#0G6(B*);H>6'#2FF1@1).$%!-8)'$..7)E!B)+:*#/E;!++9.+B@0!>@6?B4)@B&?/<CHB-+#++B-(()E.;';F>($?93D*F71)4=)"<$88-5+0'"
@r8488
TTTATTACCATCCTCAGTTGATGCTGCAGCGNATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCA
+
A4@13=?A84BC'66<,03:#&#8.?5>"2"#01"0!$&/A,!,%9/&'?9C=BG/7FH.6H-'A.B%>'&2>3B;9+'E4DB?");?081;B0B'"%(%.@@6<?
@r8489
AGTNNGNTTCNNNCNNGNNANNCNNNNGNANNTGNCAAAANNCGN
+
!!$$####"!!"$$!!!##$"!###!""!$$"!!!#$"$$!!#$#
@r8490
AACTGCATATTCTGNATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGANGTCATCACGGGATCCCATGTGC
+
F?+?9%)$$C<:6*@*.<H!E06B!)0!5FAA%G85&E,DB*%>FC/H>H95:@%@:")E:83@7&H#?4A:CB-C-$)6!H:79-&27?%6GD*+@!)<FC?<91-9C
@r8491
CCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAG
+
3>!11$C-$G/)2:1B/&!2!&9<!,4H==B.2&8;(B=,.5%FG'=.@E>,H">97$C2F8980?-
@r8492
TGCTGGCCAGGATTTTTTCGNAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCA
+
2*!+H%,","%3$57!33>AC+)'<#9+GG*3'%>6A#&.5EH).,=(=%;52AD?"=>
@r8493
GTTCCGGTGATGAGCGATATNCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTAC
+
!$+%%+*&*((*&+'*#*!)")'(&!$)!**(%"#"*#$#+&!%$$%&+$!))&'(**&$&'%##'')#&!*
@r8494
GCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCNCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACA
+
D*6D6;#()A)/$DD+(*-4%G8=7665.&F"?DA.C8.!3@&?51!25'?"2F.E2%"C;=:"5'"??;@$<8B9E?
@r8495
AAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACNGCTCTGTATTAAATGCTATATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAA
+
14%:2/H:5#%$E?+!;E3:"1).<*FHD5E>!CC"$5=/B,!B/%'67(@4E9%*,C@C9:+5(C7*,>070;&HGC(?).//C-)2C2)E2<@0*>0<%;!9"(4'2,',)?B.
@r8496
ACCGGCTTTCCTTAGACGGATGCGCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTT
+
+%6!/*F*=G)53$'41>%;.!,H/?'/E<C.?88>(!:8=F!...1"7F!;5(;34D'9
@r8497
ACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCNATGCTGCAAGGGTGGCTCCGGCG
+
7!"4=@99*6)825+6-7A@!-7*<+%"7-?)C(AFE'D#%/(;EC<!9*4E%$<?30G&,3F8G<0F3+63.5AB
@r8498
CGNNTNNNGCGTANCCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAANCTGAAGTCCACGCAGTTGCTGAGTGTGATCGANGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAACAGTNCGCCGGGGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGAAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCG
+
'(""$"!')!%%*+)+**)&!$'&*"'%$$&%)$$)&'(%%+#"&)&*#%(&!&'"&*&'#%#(")(*$%!"#%#&$'("%%!$%(!"#%*)&##*+!%+"$$%"'%%$%%"$&)$&""#+$(**()!+%)%+!+'(%()"+*'($')#*!%+'#*(*%""$%*$&'#+'%&&##$)!")%"&&)%'"#&""!'"+&+$!!*#!'("$$$(+)$(($!(%%$"#$+'"')("$&(*'#!+!('$'#%"'%)+%(&!&#(*!%)*$$+$(&&'!$'!)#&'&%$!"&+&((+%*!#+#&)%'++$)'
@r8499
CAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGG
+
',!6:B3!.<"7#3-'+(F5<../%'!,>B/.'.$%>"#&'>
@r8500
CTCACTCTCCTTTGANGCGAATGCCAGCGTCAGACATCATATGCACATAC
+
+&)&($%()*"$"#%#)$))"*+$**($)"'*)'"(!"(#&+!++!%&%(
@r8501
ATTTATGCTGTTGGTGTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATATTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAG
+
73A4=18"/3!%3($,77'D#;)E+98$-8%+F99>&:>3=HF8;/#"><C'D:H"+'&34@%0HC"(A4A?37#@EG)10@<,=D5@C0?77&??B9A"&'#$.6?!61D0HFA,F%9@1G"!8$"BFG%*@'?:<-)+:--C>#B,;1-/+3-"7<7(21>#H121@:A(&D01@7571.?#:GB722*&<FB0CC2+-"'2%8/0+=@@*@7E
@r8502
GGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCANGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTTCGGCCTGTGTCAGTNCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATGCCATGTTTTAT
+
&-$6;B'!;+24AA49AB)!741?;-&"=;8381=3E@G5*)'C7H6'1###.#9)&8/.DEH5/#F91((+.4@GHC#%HHCDH%9G</.6.00('=:$/7"=-7("1F/$0H#+AD+!&?<<C,/1#<=-@"E;C):$:/97,61A-'#A2+86&48@H#<1,9%/8.E,?."/;:?F+!4+$5;33&B;E</3.?*1EF0>>B78217;)'33&8@B=7"+/>716,27?@.>H"@>*B%4=B>?+':.0-<"3.@@/>7$@)'"@E5=5.4,A3
@r8503
NANNNNTNGCCTNNGNNNNNTNNNNNTATTNNNNNGCNNGNNNNCNGNNTATNNNANNNNNNAATCNGGATNNGNTNNNNNNCNANCNNNNNNNGTNGNNGATTATGNATNANACNNTGNANAACANNAANCANNTNNNGGTCCNGCNATNGCCCANCNCGCGNNGNNAANAGACANANNTGNGCACAGNCNANTNTNTACNGGTANNANNGCNATCNNTNGNNNNTCCGGCGNCNAGNNNANGNNCNTNACNNCTANNNANNNATCNAN
+
$"!"!""!$!"$!#$"#!#!"$""!"$$$#!!"#!!!#!""!!"$#$$#!$$$#!!""!#!""!!$!"$$!""$#$$!""!""#"$#$""####!$##""#$"!"$#""#$#""#"$"#!$"#"$!$$$##!$!!#"!$$!##!!$"$#$!"$!""#$!#"$$!!$$!##!"##$!$!#"""#$"#"$"!$"#$"!$#$!"!#$$#$#"#"$#!"#"#"""##!!#"#!$##"!"!$$!""!#$!"#!###$!"!!#!"$$!!#$!##$#
@r8504
CAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCNGCGTCATCACCGCTTCA
+
2/$,G;/>=(9<;G),<6+A;=%G"+#!/<?+E+BE218%2&F6C:2"'E4#);F$D2!'72#A-F+'3H5-!1&1%:')CG<'
@r8505
NTTTCTGCACCATTCCGGCGGGTATAGGTTGTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGC
+
!B*(#)G*/?%$;EF:@/'#,#D3@)#D2C0%!":,.>'D?).B2B90(0;0>G+$?7(3946+F#E.C%,++,G:A"*C+2:8!0E.D4C77C#,=>@57?9%991#,G;&)33D6@$D0%,.;EC6!-@F146E;=(-'=>C
@r8506
GGTNACAAATATCCTTGAAAATAAAAGATATTACTATACCGTTGATAATTCATTACTAT
+
&*"#)*%*'%'%((!)%#&"+%&"$*)!'%$(%)(%'&+)++$"$$"&)#"+***!!#"
@r8507
GGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTCGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCG
+
'2A)#&68'2)4314)@!3)15,=2+:H&F40.BGGD=46/3H19**4<<D->AE1:CG2C3&GCB8@"0A!$+!+82G>9-??"13#"4C0FAH8??)!@)0/'.;C'?CC9C?"/1<%*+3#&F7/.>C*#:EF*H@/)B(9,#/6A++F3!;(0F<(6;$(089%'A3B&F>)*89F$%+>7#'5%+#&.
@r8508
AGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGTGGCAACAGATATTGAAGGGGA
+
0:<.%-&%%>3A--AGH)EH9$>70-ED7#EE#;D7H*=!.'#;+4$-+88$*A3'>B*<3B+9F3
@r8509
ATAAAGACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATANACCCATT
+
2A)1B=,**=()1G/C.7@'"'''CC*GE3G0D%;.1DA63-7HD$.%0:5<C
@r8510
NAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCCACCAGAAGACCTT
+
+(+%$#()%$#)+"%)&+$++#(+""#!#&+$+*++'!*%%&()!")!(&**"&!+)+%&("'&"!+
@r8511
GGCATNCTTAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATAT
+
#*))*!$%#+$(+'+(*$"#)*!&((!$'(!$%)+*++!+!#(&($"'+$&&%#"%++!'%"#!&)*#+%%!
@r8512
CTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTNCGCNGCGTCGAAAAAGAGCAGCACAGTGATGA
+
&,;:,,"H!G@C,+GB?,)0"G:",8BB!>3B4+)G)$F=*7C(FG3G'GB2D<CAHG,B@'+CB:,5**A%=-<>@D+@>"G.%#$86=1-H#@B?6F2=3!
@r8513
GCNGCCNTGTNCNNNNNTGANNCTTNGACGCNNCNCNTCCGANNNGCNNNNNCNGNCGNTAACGNNGTAGNTGNNTCNNNTNAGGNGCTTAGGNCAGTAATAANTANNGCNTCATNNANNCNCNNGTGNCNNNCNGTGNTNGCCCNTNGCNNNNNAANGNTCNANCNNGANANNTNNCCNNTNTNNCANNNAGNCCNAAGCNNCGCCGNGNGANNNGNNTGTGCNNTTNCCTGNGTGNTTNCANGNAGTNCNNTGCGTTATCNGANNTNGACGCNNNNTTCNNN
+
#$"#""#$$$"!!#!#$!$"!#"#$"#"!!!"""$!!#!####$"!$""#!#""#"###"#$#$!!#$"#!!#$$$$!!#$!$##"$$#!$#"$"##!##$###$$##$##!#$""!"!$"$$!!"!#$""!#$!""$!#$$$!$!"!""$#"#$$$##!#""$!"$!#"!!""$!!##"!$"$""""!!!###""$$#$!"#"$#$$#$$""#"!###$#"$#$"!!!#$#"#!$"###!#$$#""""$!"$$!!"!$$!!$"$!""!!"#$"!!##"#$!!"
@r8514
AATNACNGCTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTATTCCAACTATATAATTTGACCAGAG
+
"%&&!'!"+$!%*%(''%"(%$"'*$)!&##+'+%+)((&!%%!'&*$&+##*#')#$*#&()'(+($!%)%!%!+!+*'%"!(&"
@r8515
CNTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCC
+
%$?A=99->!:?7BH;.$"6E#F><$(A4%-%2C<*,45A>50;HH%<;4D!E88B4'&8F6G4;-DGGEGA*B1F:)'B
@r8516
ACATCCTGCTGCTTTAATGCTGCGCTAAAGACACACTTCCAGC
+
+C5!14:<D#H.G".FEB8;$#+)9)&'9$CD1=.F;AE>C2D
@r8517
CAAGNTCAACATTCCGGTTCTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGA
+
%;5#G(:E-?*-&%*3/:<%G:*#5)0'F2HH*$;,/H!H/!B,F>H1H6(?)+(=-)D+(;5?H=;*"=E/48:+2#$"*A
@r8518
CCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCNGCAAGCATNGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCA
+
A1E#9>#F:"$B/1(F:'H9'AB97/3.5)F&9D$)B<=&AC#:??-B::C0-G'2$@-/HCE3),(),'!,BB?H/G91C/!90,BFDCA3:8<'?,D:?'BB7<<'*!1E"#C3&7$:?"$
@r8519
GGGNATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTNCAATACGCTTGTCACCCAGG
+
B".E>(7;.CC'BD2#5;<BGA8HD*&!*BE,EC&A>6*7(,GA0?<04/5E7"652<G$5)F4(12;!+*A>C*90,C:7$/&94#H(G(4&G*)&AD#GH;@&>:D
@r8520
TGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGAGAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCG
+
B#B6.$6-2-;=/09D)3:"2+!6#FH<5&%<&.0.H;92,)0FD3(("-"$1#5!EC2@C:(4-FG31(*$'2;?H/,$C>26'+>)(A'=.B-B6?B>%68!;A'##7785907BB!!.$;+$A8:!-C##@!B1H0)H/F:#G9=HC7!
@r8521
CTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCAGCGGTAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGATAAGGGCTGTCGNGCT
+
?/E#%,6.343.AA/<)G7'&52->@/,#&$;0+0570E2-/H")+)GDAFB,F?<8)4B$5(D36>F#;*2G+D-@FA<":06E/3&=H#>1:4A6+2,96!$+'';,0EB:)++H#&
@r8522
TTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATG
+
,G7+7HA:!!6*F,=9/9F8*D!2GCD:93%#8B:,8'%CF)1
@r8523
GCCACTGATATCCGCATTTTTAGCGGTGAGCTTTCCGTCCGGTG
+
/25+1;";6>&F$1)'6CG4G&#B10)3>0#!GD.'@%!G4-2:
@r8524
AAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGA
+
HCC297.:4C/21'2D!<?E=0+)@%AH980"D7$G/89/?#F,*;@>5'='.15('0=F381B
@r8525
GTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGANACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGAATGATGGCGGAAGTTGTCATCTCT
+
&<:9D=C)'.#0/-3%338+D7&:#*+A?-)><4+H&E,"B+9288@.'F"D45;AB3-EG664?<@/";H'@-*B0(A1C?/9!"H;41'--(,.7#9!89>$96CC<A>18+=B)@@66@G251=$7(25#!0!H$64?7)F=
@r8526
TANTGTCGGNNGCTGGTTATTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATTTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAANGGGATC
+
#$(%'!(&$''*%+')%('!+%)$")+#%'!%&%)'#%%('$)&)"##"&%((+%$*#&+!!#)"("*'!!$$()'('''!#)&%%)&$+#)$'##(%%++#$$#&+&!'"!*$*'(+'*&'#(#$#$)+*)")$")*+#+!'('*#+*"(&")%+'('*!)+(!*''!%))++(&*!!#")+&&%###"+*!+!'$+(('*+!'!)"$#*%#')&**'"!*#))%")(#**
@r8527
NCTNACTTCCCGAATAACCCGGATATTTCTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAACAATGGG
+
"#$$%%"))+(($!(%*'&(!!&+*'+*((()*)&*(*#+&""&+$))$'()+&$()&*!*%("#&%)"'+)"!#!++")##
@r8528
NAACTGCCTGACAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCNCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCT
+
)')+&+#"(+!!+!$+#%%')%'!+)(+(+''%*'*!(&$%(''*+)#$(+)&%+$)%)"&!'&%$&+#()+'''&)"%'!$+$+(&+&*$*$%!
@r8529
NTTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGTCACCGACATGGACTNAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTNTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTT
+
#=4=8E).4:C7?E0)8'!'<'/-(DA5;"9D4..E33&F='-,G%*,F=.FC(&$(=;-#/08%#G#8=%.>B!%/?-;91<7'><70*?3$4>G;8AE"/.H*E#3$H8)1&3!@B=2&'84':@B#4(.8HG/.?0B8-9:/8,?*/B=#22>.36+)&>B=A:H37*C$>F+67(>6:.@@-A6:8?$!!G4&375>A<.8%.#7$:@#)D<&$8;FG>%1)3<"C"31=/:A6/.G=.(4'B
@r8530
NATCNGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTN
+
!"**!+$)&("*%#(#%+()!&()+#&'(+#'!%"(+#)+*+"#'&+""*$("*)$%!%"%%!'+$(&!!$*&#+&*($%!&&&#"+("#(*(*!*!
@r8531
NNANTAAGCGNCGCCTCTTNTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGNGTGACCGCATTCA
+
'#)#+)""%*%##"(*''($()#)$&$%"&!''#!#*%!!'+'++(!"$+'+$$(#(+%"'#&**)(*$*(&***)$*!(!$'#$+&+$))#(''&#&+'!!!!"$(#+!$+&)"+(''"""(&"%*(*(''+&)!('$+('#**)*+*&")!!*
@r8532
TGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGNGACCAGTTCAGACGTNTCCATAATCACGGTATCCGGCTGCGCTGATCCCACCNCATTTTCATNTCCGGTCAGCACATTTTCCNGGCTGAGAGG
+
+D&.8C8<#69#7E&CF+D3>0F?0;3&;$66;B7E-F!)$>"$/112(+9A*@($5=-0;5+24.3/173E=$DA$8E@65H?HC;!@+'%!1>#1=*-=B'58F#D=5:%#(D:3>%%AHD@D;';B$=F%!
@r8533
CGCTACCGCACTCGTCACCGCGATAGGTCCAGGTGCAGGTGTTGGCNAGCATGATACGTCCCGGAAACACAGCGCCATCCGTTTCCGTCGGCGNGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTNCTGCTCCGGATCGGCGTAACTGTTTCCGTTGAC
+
:%FE)0D?0*&);DH6$G4>/(:6%:(7"<6G$A2-4;3=&?.5"=$@%DB/>A""62>G)"H!5;A/=+C83-CH:)*9#1,><,<,@45FB8)8>H6):!EH8*90#EAH7%3F<8;:7<+/*(6?$"(@9&92/:A:4;.-B@6@!5D94F.@)7=$6G6>9>-18'%!233D&0F30HHGEB@H$>56'/+'0A%
@r8534
CTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCC
+
=3EC0,D,>=F(/=H33#0,C<2G1D(;%#?5EEB8&D7.E+='#4?F:<6%8#8D)2"CED;7+!6!5-B?A&(/4#C23C(69;2G(D$.4.;380"!G;%<!-F2-.3%/&*@3&H53:(D7/&D2@GA&B-F'0H<F67=%&04*AF)-E6%<260+8#+&+=:(<BH:$H
@r8535
NATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAA
+
'%4CA(H+6C<>B0B+<%A#!2>"0H*&821)!$"6)3&2H5")(G2.HH")9+#,B/.--/(E#0#.((,5
@r8536
TGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGT
+
490:,-C6%$=1,43!C+-E*G@3%08D?1#46!6&0:,'GB/B/B"(A'3%;>E#<'D!984"0<'"G(92/+35F
@r8537
GGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAG
+
+"$+&+'+%*"()*&%!&)'(*''#+"'!$&"%*&##'%+!)*(&**#%+"'+(""
@r8538
TATATCTGGCGCTGAATAGCTGATAATCGATGCACATTAATTGCT
+
4;0@)'<'D@D>0A4#E(#>!"%1758H$#H,(G*"$->;1.CG)
@r8539
GTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCCATGTGCGAGAAATGACTGAAACCGTGCAAAATTATTATCACGAGTACGGTGGAAAC
+
3F>0!2C1"?97=D"'$!EC7D<;!%%<<GEHD5:2H@3F;.B)9!")D#8@/-B+1?(9G$;*')9;=A+F=G?:4;/):=G7-8-F0H5&9B9!!)8?=A$".;6)%,@'D'E2+<G(2B+&,%)$(H!;.06-1D>:<7H3>D%9,CB@?9(*>9--D?2:C=B)!=$G$864'(266E=%E(>9&(
@r8540
TGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCNATCGCCGTCAG
+
?*%%&"?#71537D.-H5<';*/H;&@:#E:6DAC830E',HA009B1E+H.>):28-;9#C*@,A).&$(%+-3D(+9"(>693%B.HCCH;
@r8541
GCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATATGGAAGAAGAATTTGAANGTTTCGAAGAGCATCCTCAGGATGTGATGGAACAATA
+
7=!*9)D+,D28C%99AG0F<!@36"558+=?94<%3&9H%<EH-,-AH='EH?#H2-7-=1?2&='=H(@3.B?507E->C"!98!?9@B@C*@49
@r8542
CGCAGATAGCACATGCAGACGTAACNAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTGAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTAGCCTTTTGAAGAGGATCAGAANTGG
+
-2<-5C/-EC1<B$:44@B65&+E+7.!:;6?08<%('&?-3&?(+%'12@5;043CC53*0"./7DC@*6$:;6==;H&!=,E=&G9H?F9H$#H3*;H0#302$BG5%3CG4&?%AHE45"<80A@$!&BGH:,+%,?AH9E$F:-.8$@,A#H<$+'E+.@+4(-<.//1!(G8+,<94"C"C@6;8!=81;D2-A2$!.G"+!B':H57&)6!CB83A0B5C@#C0G3<+/-@-35;H="*:D235?+"9=#)=3&9*?.,3;F8<B)1!B9+F?2H!9??7=*!+(F+'E&0-7+B8!5&$D
@r8543
NGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCNGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATT
+
%"%+()$$!((&+!%(!'*!%#+*$"'#"'&#&$%%#$$&&)%)&'(!+$#+'(!%#""&)$!("!#+"'%($!$()()*'(&))#('*!#!%*&'&&&'+*)!#%''(*$+)&!#%+")!!%((!"%'(#'
@r8544
CCTGTTCAATATCATCATCAAAATCAGCAAGTTCATCNTAACCCGCCACATCCACCGACTTTTCA
+
>)#"3%C-8.&6":0E(H/51:A<(06=)9&&5G301#=HE.:;"&6/6@'C=7-G/42A23A25
@r8545
TCAATGAAAACCAGCAGTTTGATGACATGGACTTTGAGNAGGACAATGAATCCTGTACATGCCGGA
+
D,-/19B/?<1")B@%>86E7B-"8C09D"'H6208$@-;%$..@"%9%"+:72%E;$A9"0CHF:
@r8546
TCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATNCTTGCTCAATTGTTATCGGCTA
+
</(BCC#A9-B3E1B8'1'3F(5&'B#&H3C+:-H,(3=/8:=E.?DA*D&2.CG:<.-:&
@r8547
NNGACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGNCTGAATATGTTAATGAAAGAATCGGTNTTCCTCATGTGTGNCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATT
+
!)%;";&!$6150BC("#49&5E#.%-+#58$%D.*(++<./@#80#:B%$A2#0);0-@?"&E8"$$G8?A<2"E-(B$!G3A;9>%"?G0C>7(*+=-!*E'&:62AC>C>/G#;)5B("&-,$8FA.4D@;)4HH)&>4C$83+HG%-7<!6
@r8548
CCGTGCGGTTGATATTGCCAAAACAGAGNTGTGTGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGG
+
+=&A+729,>G4DB*@,+B7$D<?C(8584/#22<.E:F3$6&++;AD4D.61?D,C<68D4CA5:)$.=;B
@r8549
CTTCTGAACCAGACTCTTGTCATTTGTTTTGCTAAAGANAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATT
+
F#-38&G')E(/E:*.!!&1##AB,G"'4DC7<8.<>5&3!1D?B<)3+A)?=3D)7H4/)-%9%81:2FC%F7/5()
@r8550
TCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGNTCAATNATT
+
15#2<'#9C4%:4A&65$4,0;8F/77)7HH/7BC1?@9<,"@0<D.#@B@(E9+4=:>D</%(:3G8
@r8551
CTGCTTATCAGGAAAAGCNTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGC
+
+#((+)%+#("#"'"#(+&(&!'*$!)"$!+(')(!')+!!!%$#!&&)+!%#)*!!%%&
@r8552
NANGATNGGGGAGGTTACCTGGATTTTTTCAAAGGCAAGATAACNGAATCCCATCTCGG
+
'%!#*&$"*#!+(#"!$%!*)!%&*++)%')(*&$'#"'''$%$!%(&)!)+#*#%)!(
@r8553
ATGGATGCCGCTGTAANTCAGCGTGATTTCCACACCNTGTTTCTCCAGCGTAGCACCGTAATTACTGTGAGCCATCNTGACG
+
#5C#G$B&D>+)9&%*H*9$*!C4EDG20&A<-@&32A'@C>G:!7AFFF@E,E')&2B3?E#+CFCE?)HA'(&%5@%>&8
@r8554
GTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAA
+
($17A%=DB,(%53!*<?1A#7$<B<<.'2B#%G.&E'F$7!B0-;;%)?91%3>)'*-0FFB72.(G'4B2%BC8
@r8555
AGNCTGGGAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTNTTGCAGAAGGGACCGAAGCCACATCCATACCGGGTTTCACTTTCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATNTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCA
+
'#%&*+(#'(!$)++**&!!%(%#*'(++**"#%%%*'+#"#++!+&")*#()&"*($'#&*!'&&'%+!!'#'!+!)++#!*+#%"$$$%)+$)(%(%"!)%+!*&)!$$%#%$&''!'%&)&&'"++"*&!'*+(#%)%""+%!%!$%$")('$#)%!*$%%&!!"($+#($!!)"%&#*#$$%((((%!"%$$#!)'$!(+&$*$%#"+$%(+*+*%"+#)$(%$#(&&'!&(#*#&!)$)!#"$$
@r8556
TGTANNCCNGACNTTACGTGGAAACCGGCGTCAAAAAGAACTTCCTGCTACGGACAACAC
+
&'&#!())!%%%!$(+('%)$+)!*#(+$"'!&&#*#+%++#)")''")*"$+)"$('$#
@r8557
NGAAATCACGCTGATTTACAGCGGNAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGG
+
#0D>?84B+!0=,>&7CD1,8E)*%5>63&$81F$@F$+53?H8E=7C>?:-F>B$#70!<#D>0
@r8558
ATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGA
+
E7-#8HBG,*A($$A/B<@/64A:8E'8)H'1"*.#&%,21<:
@r8559
ACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCNCCCCATGCTGCAAG
+
/'2/9:!6@/D4)9A=*=7G>290<="?@;",(49H6$>'@--.EG!+A%/;A&&@1FA>20EGH"(A-F5G08);%839"G-;1/
@r8560
NTGTNNCNAGTANGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTT
+
!&*"'%#%%((*!#+)*&'!!%'&("%%"#(&(%($'"$$)!!*+!+)*"%+*%'&**)+$'(!#%#"%'##!!%"&%'&+''&&+!%+%#')%%%'%)&#('+&%)"'%$$$!*)*&("!)&(#("%!$&&$(')"*!")++!%'#+#'"##%)(&**"!+"*#$%'(!&!#+)!)'"!$)&#)&+($$""
@r8561
GCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGG
+
;>2":!7*';HD<#!.AAE/9+&<:++7%=99A-3'D!GD!"??HEFA#?%?3A8)F6%HC;")G<GFAC-/.B&!/+-2:*2,8F,1H!+:1,C3?&=")0!=1?1;C4"=*!&2<<"7
@r8562
ATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCNTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTC
+
7/+/H57%'A!)9!52+6?!-7>8)A!(,02:DC9!5B5'*)->'9@<D'!#3&"=1DF!;)>H-$BD!@#$35-%-C&$(#C1=!$D4A866@2+/&!(3+9=;4-!6%>E+'/#D82-+02A>,*0559>1?AF
@r8563
TNTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGA
+
C"(1&-AA0/*<A(6-,/-+A::(/CH/H$HC,G7@05F4",*./$A'2D)/1/3310DC8H0"!(B/B7/2#$5<!1=2703%1-+1)="<>?!73('C>1E@E41;=/3>!))6;")97==&<9?-$9?9):D+$6"1#9<!4/*'>$A5A9G"@2(?'D7C-")9?"#-0*:6,'<88&7EF(*&)29'=53H3%C>;/?69.6C&@:C*3+()8'&G,$H*4,<.!"64B)*.7#2:+5*='.;A*GA/<0.*4?%*5D7C97#@/#1-,$"#/;CD!"82C>=9E8C:3;+?$12F'4H+01=:0<?9;H)"+B7HE3B1H:)'?3-9.4A.+,H/GB#>?
@r8564
TTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCC
+
!<%#$EFE<)56E)3F-B8+*(B9&1:;#&-&E:H.?)4.458?$F!:<2D1E*$CDD>H<H)$1*AEA6(D?@A@;87)7$0A8.1.;19'C89/5*+4&$C@%:*;B9?"'4$<=9G=++!83%)%9::
@r8565
ANAAGCATGGCACGCCAGTCGGGTCGCNCCATCTCACNCGCCA
+
!"*)+)!#*!)+"(#'*+$&&"#)*%()+$+'$&()+"!%%**
@r8566
GTAGTGATGAAAACTTTTCAAATATGGAANTCATCAGCCTCATTTCTAAATATGAAGAGTTA
+
,&0@2'E,$A6@<-7,3&$607!1H)94(!?1-@-CAC#'#:.)+)E8:#/961FF7/200"
@r8567
ACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTNTTATTCGCATTCACCCTCAAGCGTATTAANCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAA
+
5E345+))GD@.!FF>.@1CHG>)<.#"3E3E<0!@'9'(('E@9$!?0%3'+205BDBG(>8*-G"7'G/+(4"D:<*@?>"B5;$9)@E'=@07D4@D<C=;>F8)@*2,(;'/%9<.-C=B.$8,.EH<>B$"@,A<192$9@17=H=?
@r8568
TTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTNGTTTTGAACNGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTANCGAGTAGCATTTTTTTCA
+
$2F=CF9@:&3('7$&+!HC%<4B+:9-)E+;+.7D9)C2HED'4/:D!H1/?@9C89BH!@-,-#5,$*H99<-.=#>+:B62.=?(F?*1!0F49@F98FD!D:"%'+D$-B..F*C16+"5?#/4'(609+%@2,>*@@G<EA.E?$
@r8569
TTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAGTAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGNGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCNGG
+
/(*8>H,@,>2$588FCB&!3)B1?7.6BG'03G2?5&1;).-!@28>*++=)GB,>-E=H5E.>5=H+>!3$0)D26?.!'C'2@7B@!!&9BD)!('D2B@+*)85F6)B-%;G4D.?H7G;50G.*+G9FD/DGG;@?2;'073G*9HH59G6C>(05;7+D5?&2//9+#07!79/H'&-47"6B/9$A)*'B>F<A?HA$<-&H&D9<=
@r8570
CTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTT
+
@*D#H':!H035.!F/H(?G*,E(D?8:.<&4C7C,"=<C'BH#<;"<)/7B:>7+=CA(93D@$?H7,::E87>%A:D,0//(+9+B?7'5EF9
@r8571
AACTGCGACTGGNTAGGCTCCGGTCGTATGGCCATCGATGGTCT
+
DA'%-BG'G#F-:D'F'4(?(6C+<(1-=/34&>D#:H7%*'17
@r8572
GCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGCATATGGTGTTGTGTGTGAGTTCG
+
-5HE!2.D"==%-F>:</%$%;;+=>.37>#+,C$HD$+6H:-1A&48/*'%/A9!#BC$/'#4F01
@r8573
ATNTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAAC
+
)''"$+*!'%"&(!('"("(")$#*+&**#'!'$#'*&+*'&!*$#)&&#"%'+')#'+'"!*"%&&($+*"'+!(*#+%)
@r8574
CGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGANAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTG
+
14453G=@5-@9@F'$!#5F=5C,("4*1%6H3F31-/(-!-5+9HE(4,G*!E0@G!2/2D:;$-3E#0&@E)C=%A':&5-)<5:5C+*?&>B9#E*B"53-,;D
@r8575
AGGTGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCNGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCNCATCGACCNTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAA
+
H)DH!D7#&,@0<@B+@:)>6>204@0-(<7%*AF=-A#4@?8:>#.E6+'2@*3=E89'<*"-@5$D,3>DH6E+*(H-2;4+.+(H678DC1!-=8/-A=H4G#H1'623$H(,%0D47;?4H#A?">>95009)<BD:(BCA83=9C94B.D.>3!2GB>B/<6+F@0@E:8F+=<@/82-/&72'&"E8</2F?!7,F-<GB))E6'H9,D1":/9*'<::/*)E@'>*CCC>B+).>FF.:9+.-8E8/+=/1A:,$%"5,*$D;/387-%(8.1E=.D>FH,78>&AB2$E9H1$F4'.59C"7E12<2#.%B1<@;:$D&,>8%5$4&<E*5B,HD>,>8'+$:<+%B-B&19>@B!$HA$+19=A7!9*31C2$;/./&/"A25$G83F13,@6?:@G&F/+>E7A2$G<)#%9,$B*))@4)(%@-9D'.$<H;H8:#,&4ADB;810.4F.$
@r8576
CCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGACGGCAATGATTGCCANAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTG
+
<FBA(@=$%C/>5B<3>F"#"5A+,AD94D&G5-B7(*:EH>/GH6G%:6*,27"/8?G:6+#?40!=4:'%C;E%*B;EE=7BG&2*>=>.9/F8#+,#H>G>B+:8%.(A?/2<!#(>-%/(G&&F%14.+%E?:F(;@68(4*H6A/G5B=H2,(39G'C!@%DH-"6#<)6AB(4G!#'6;(+HE2!5@)!B-<?5GC2$:=/;CG:9=-15D#1/5/%&25"?,C.%59E=8H
@r8577
AGAATCACCATTGGTTTTGCCNGAACTGTTTTCGGGCCGCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGNAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAG
+
B:@*3$.5C#1$8-FD9F:)=.:)H3(6@)!@1C/AF+C*&:.)D'-#">H?H%*?*#H30FA9/#"(9=%/.28(6D8,E2&%B6#,3H!(,"-54*+20@=4C+G>7E?EEE2A8!<.1'!5GDD6F,.C:+'-4*/'@E:,;B>D=?7G>!;$H"#C-CHH'%@$F"/'-:F;!C$+60@E)'A1;D-HF+?30@)B8F$#?/13!)=0+&A3%)@.1'GHH<$;E57>&54A?;$+<C=CC0B")5)7BF?;:71-&,!/1<"#D:F)0"#1(H'1E,0;21?#)':H;:*>5FB)"64'(02;CG.?G43##*B427?//(';=#&6,BE%8-%09?!(*)&8E;18,8!6/$23C&#*#6%82)D;*#B));G!/#!G4(D%CH
@r8578
ACGACTCCAGTACCGTGGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTAC
+
;@@HF.(64&""&C).<F.?(2'&D*)25EE<'BA2=,=D>(D"%,?=&E77@
@r8579
CATTCATCGTTTTTACATCGTCTTCGCGCTGGTGTAGCNATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTGATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATC
+
D'$)/,C-?F:&070!3F=1*<)8G*=0E&(/>!=E),A>@<*28H#;G'98!+>8!&HF0%-,&;:3F-/!3'B,:B%C8:-?C>8E::35#(2""(?%=(3(A$<9$93%1$4E8@9;:#.$9:>C5F7%F+?.)<G;302?156F!1>,E*+.++4+@#5"?*@$DG07>0/0">"09,5&-::'.5C'=((B%,+3;'E;B)%!&-.!0G#+C'B),H=)&5F%25,11GB26.<;A!
@r8580
GATACCAGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGG
+
H&%-8&22'3>;<=32"&)6=61";B'11,4=76B?*D)#DC8!#)2=E
@r8581
AGGTGACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCACCGACCTCTGTC
+
/22?C+D,0#3H3"&FE9+(D/0;DA$H=+?;F<EG!E51!B78'$9D6!<>'"3E.++3E714"&+7
@r8582
CCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCT
+
-F%23!D,A/6)%%)"8'*%/!CGD3F$!/5."H=F')?>&@4=/%2,5F4:;?=E="0A',;C/=<BE-*6$8D:2CF968D2"%H.'6&$)%2418;":*A84@/"A>!':28%/28>FB1*8C?FD/10<-%-@@.D!07!*:4/'!)(
@r8583
AAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGACGCGTCGGATCGCNAACAACATGCCGGA
+
3?B9<&="0)#3G2(G5F:+6635$./>H2,4!E7+C'&F:B7&FH6.*1.&E67@G-*&B*"12H>)A3
@r8584
GGGATGAACGCTGCCCTTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGC
+
=11=$9$26<'&?"'?C50C4,,61,<?,$?;/@>-:,%5%9>):8F#:18BHAC1&7,,D6&/1$83/2;*7H$A:,4?&$>""7&>(.!FCC6-5;$#11H>3&E4E6
@r8585
GNGNNTAGNTGNNANGANTNNAGCAAGAATCTTCATCGAATTAGGGGAATTTTC
+
&)'&"&*)'*'!%$%%&!'"#()$$+)")"+)'*#"#""+*#'%!!*"'+#"&%
@r8586
TACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTAT
+
?1C)H:'$?#;+G;@/(2>>:0>HAC>+*B;G:H5$"5B+>$
@r8587
CGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGGTAGGCTCCGGTCGTATGGCCATCGATGGT
+
2/(D&5C??H=95*%C9><)C8A#E2.'#G.,<<*"&,,7$*6D2E/+&)3:98D52<#3(/EB'A?4#5H7H9*>:8(3
@r8588
CACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGNGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAG
+
.#BG0'$,@,*:B!)&$&!&EG#G+#E)545.,)#=2CE6&4H?'&*2(G.7'$>A&?@/+D<>.G58&(@4096)<"##A06C)->C!"2!25EG',,,/
@r8589
ATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCCGAGGGCGTAACCGACAAGAGC
+
8*0F65!0D-1CAH#H29($0#64B",,&1+<(%(&-!>-2+22<.C<>-E+2-=#&&%G"=*,%$A3C&GFH@3.578&21EHE.)4G#>E6
@r8590
AACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGAC
+
#+!"++(**$)&%(++#))*%*!#*$')#!$($+&+!'*#&(!&&%%(")$"%!+(%((!*%+'"!))+'$'(++)#(!)*+
@r8591
TCATGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGAT
+
=-/6)&:H+H%5?C%&+8F79E3=@B5;/<@E8H;AD'/6D(+!!>>=*;+6;.+:32F#'3%,D<E*"<7DB/G81F!*$793<"!/.)B+CG3.&6/0##6#?12H;##F18;9H%5D%+*!,$9,8:F+6.'2*AF?<'2)-F&$6
@r8592
ATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTNCCGGAGGATGGCAGCGTGATTTCACG
+
D16=D)%#6&.,412,5%9=&G>*,C&64-;1G@B-H,HAE,G54:G;G!(:8&9'=DE!(H)
@r8593
TGATCGGTAGGGTGTTCTGGTGGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAG
+
6&H3'12>1D8C+1>70,=C5(60%%0)'895/*"?A@<8=C+C&3(<)CHC',?<F'5#>+&0F9<H>17.>A&=$.-758-,?"/A)84)=2;G>0B9'((G3(E:%=2@A/F$E*/<7
@r8594
NCNCCTGTAATGCGTACCTGACCACACAGCGTCAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGAC
+
!'$'$+!!*+')!)$(%**+"'$%'"*(#)*('!()!!"*"("$"+(%'!"**#%"%&$%'*'!%&$+##'"''!'($#&*"$'#!#(+&$&)*$)*)'$%!(!')+#%+$%)+%!#)'
@r8595
CGCTCTTACACATTCCAGCCCTGANAAAGGGCATCAAATTAAACCACACCTATGGTGTACGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACG
+
6<BBB?$B/.A2,5'+EE#/*E96.9E3@,E2%A7:51)'9E$G:(&3=.;<"43@9")&0-.:E"H;2>-.<(DEG?)6:,+">2G3=)(C;!4)@7/$56B0()=D&,(3?8*@)56A.0"'$&988%&
@r8596
CGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGG
+
@6$>#@F'E.G"F.$>H(&1CC%;?$<##9/813.6*#F/2;6)<'5946B&$E"428?*9!45;"4,/
@r8597
TCTCNNCNATAGNCGAGTNATNNCNCTNNAGGCATNNTNNGNT
+
!##$#!#"!"$"#"#$#!"$#!!$!#!#""$$"!""!"#$"$$
@r8598
GGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGANAAATANACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAA
+
#;!B-8>%.25-#F!9598?*CH!;F&=.$CE16'DF0.%@3#*#>1B@DA=,27@;>$6<&@<C7=(CC6B18?4><)D%,)D+-%'#'&-+??B6@61;'>":-E/5G=<)AE-5@!<;0&4C*"&'.0:<;)586!/$8(&=%?7-;94G*C(G8F.+*=8"H$H#7GE6>$*HD::>0>)<-;
@r8599
TACNGCNACAACATGGCCTGGTGTCTGTGGGATATGNTGAC
+
&$)"&(!+'!(%+##*&!)+&)'$#+'&((''#'$!%#'+#
@r8600
TTAAAGACCTGACGCCCGGNGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCA
+
&D//).G(=?0"H!4*(BH*4;2)$>:G?%-D#02'C67@7&>/*(/'2>427$(04%'50C$B3'@=1.;
@r8601
ACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCATTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGG
+
A)8)!%!4B<'*E'57%!(?>36F9=D4C'>:*#2+2;7*EF+0.'$<$A-.<9@)E0$;:@'+-$)F?*3HG-<""2%!(,D=F07F.6F33*,B0B)15,,%#;#/B<<AC"?>6C,$?6H71#A;G#*/(H@A2:>6B!H4:9/*1?G#@17,,4@,+$@
@r8602
GACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGANGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATG
+
9F;8@5+:C&&)C%>F%DF%?"5?AB1BHG@>"FF2>=1-<5A8(2D964(>>!#8/$4C$G3E"7D:$4F&G0>(-+9)G;6(/=?32%$!=&.17$.6!$D>1<:7?56)=:<BF-2C3;90-)F'3#0:(';+,7(2#F2#CDF<*F9;(;$"/38A(-.19=/@H
@r8603
ANNGTANNNGCCGCCNNNCNCGNCTNNNNCTNTTTTTCCGGGAGGTATCATGCTGGCCAACACCTGCACCTGGACCTATCGCGGTGACGAGTGCGGTAGCGNTCCGGCTGT
+
((!$$##&&"(%%!%"#"%&('#"&!#"!$&"+''$*+(#)$&+"&'"!*$#!%&)$)%((*%")##$'"$)#"(("#((!'&&$+'&$+&+%'#*#$*&%%+%**$%%('
@r8604
NCTGCATATCGAAGTTTTCCTGCCTGCTCAGNTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTAT
+
(:((7590>6.H#0G1!4$1GH>A!,=E$81)6<!/?&$F.678.@7??0:A<@'#;3,9FB6;1<""+H0"0;1<!;&@7>2B2>"@10*D43/%!6(C&'/;*3EB<531!AA(*BBA./%!,'C%F>E#A@:8+-;
@r8605
TTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTA
+
243#/72,G9D5"1C8/1"%E)0,8&1''8(:37@/#E@DA=6+3;+.(9G@.4"B$#8(1D?67G-="F68=!#26,$433;);?%94'CBE$A'E&0,"E#+A$+G"#.*$;?(G2<FA";=(2,"-H**"
@r8606
TATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATNAAAACGTATGCACGTCTTTACCTGCCCGTCGCTTTAGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTGACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCT
+
%8*E>8.G/F"":</!"1(HFH0FH6EB>3.%0B;E,8>D&:!62*G.8&<5AF71(5@<3$2GGC6,742A0:G,2A)<&?3)H#=C-61@382%8E-/3"#/-),06#.$%?C4./9G7"55AEB9=>106,'#;H9(9"$$/G6@:G!;.42&80=D>GC$*<#0)6+>-=3G;6)7F7C3??'?7=E?%*7EE+<A-0EG=C@5:H75/>$E+55D%/%>EF>8)#-*F)0/7"@HB+0&0"3B#F=-D6G0EF#30'8C5@.16=CE+9E1)DB$=-0/:0ED/<+!#..0,C1<C78H*=5CB)9".FC:HB&#'5"-;)9,;=!2'!*;.:2B-&9.#G=#,9&,?%:71G8BFC:"<D;#!;C(3!!:,7D,/D9A61A8(6?%E.!A1.%1$3'GC?E8EDF=
@r8607
CAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACA
+
)=3B'B-52E7?1+<@@.27B&3/H;=+9&.,B):@E7/0#?)6$'
@r8608
TCAGGATGCAGGTGAGTATGTGCATATGATGTCTGACGCT
+
-FA,-B%2+%HDB;-,F6H+4CF9E/A'F8:'404.F5>&
@r8609
TGCTGGGTGTGGGGAAGTCGTGAAANAAAAGAAGTCAGCTGCGTCGTTTGACACCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGTTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGA
+
+AE5%F58'B(G)"D#3<(4'?=E?085>C'",:-103(82E?+3%5F;(5!@,?%?/;C&C+9D*HAG',())/>)A$+6G05A;(2+"7B,*!5@!(H@:6';8A'++/#"@-A:>%+1#@:<'FBF22H$1%E&*F35A:?&@(C*36"D$43A1*;-2B85H+$5#7B3/CB<@
@r8610
AGTCGTAGTCATANGGATAGTCCTGGNATTGTTCCATCACATCCTGAGGATNCTCTTCGAAC
+
,94=;"*@!A!:-$!$@!2B?F%50!=F23,-F'0,A+5,5#H1$%&&$A,3.6/%-4/%)8
@r8611
ACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAA
+
?"&3&9<09G-;7/$1FA=9@*=E3./A7>=9G$:@41@/&9'>0:.B65"F::'<?(H@<0-8%:AB)G
@r8612
CGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGATGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCTGTTGAGGTGGATATGNGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATA
+
EH(BC@D=!.H3"F&1G0:6""D0.GD%'F0!9+%&$0GH4.)*.G)#(+D*G#$-:";5B/E4C+$0'45@A5)2E:/4%>>#4;=$$)(("(5)=,B><5)"H100(CD865%+90)'5#4?)-=-B:4C'F&#'%C$6:0A7%=HFE4-,44(+G/;;2#=4?!@*518E'F3<33%B165*?)D*.(<$;5+#=/+&&%9-3*9&FB2:/%;*FD<6@<,"<*>>DH@!0?.&#38D(+39A,G,5D$D;E-9)+64343+4D93+A
@r8613
NGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGNGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTA
+
0;67:4.8*D#BEE&6&)/'6&D'A%0>=HC2C+>3;!%D,/@)'!=5E#;4"A720%!4H0/E(4<E>43/5&*/G8$6'#7#1@&*%CC?%)CF%7E*>3'>BH>A&!/GDB%?5,G8EC-2!B-(5,(1:+0,,$"(E1$968,BD.0+39</H<9(
@r8614
CCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCG
+
?H=17(.,>&HF:E,@8+:%:5-*9301.70C;B@*%=>!-?4<(4F;-%8?"F<%F54H<141
@r8615
GAAAGNCGCTANNGGAGCCTGTTGGTGGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACANGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCNTACATCTCGTAGATTTCTCTGGCGATTGAAGGGCT
+
&*&()#$$"$!!+!")"'(!$&*%)&(&*!*"("%$()$#(('(*&+)%""*)*+"')!%""""#%!$'&++)*""%)(#$"%+#"&*'"&+!'**)&'!"'$%%(&$!&*''!"&!!'!!'%"$"'&"&)$&&#(*"!!&!%"()#&+)#&$$)#*"#&%')"(')#$*#&#)#+(%$!&!'*%&##")($"#&+&&"!"&&*'(#%$'+')!)))(+"(+()*+)!**&%'!#!)%#'*%&!*)*!!"$+
@r8616
NACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCTGGATGGCGAACAACAA
+
!D8!,)/4G*G(7$+(!2743A$F/909!%?9-$0*7(E8/@843%F0"#$G05&'"/+-!67D>CC06:F2"D1,@)<=%:@;1;<(-4&@8@
@r8617
TGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAAC
+
%8G9#F+(%@6=+0:'9E7!C=84(H;BA%5@#5&0F*?.9?.)BH6?;5AC&763(3<.6&,F@#%
@r8618
GGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTC
+
4C$,F".#H2E#!8-&FB4A#3'D),1:..46-:BD>1$@7=A,57.=H8"DF-(A9=C%
@r8619
CTCGTGCGNAACGCTCACGTCNGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACC
+
@5?/8**.FC7C03)/0=%CF>"/0C.)#7G+-$3.27=F'!!*#0E0D726A5+/#3/>E0?<4:,$FE+'$&&4#>58&B@+@.&(A=3E--.<#5>:>E2B:0G,;;D.8*!*9@&
@r8620
GGCACANAATNGNNTTNTNNTNNACTNAAGAATGCTGNGANCATTAGTTT
+
'*!$%$&%)#!%!(#$*(%"("!(*'#"*($*%*$(&"#)'*&&$'$%+'
@r8621
CACNTCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATA
+
':C@">?G06D#/C>//&FC!7&$=.C-,=G-%50=&@'4A%(9%2B4(*,2*=$32"F"?04@5%%&*@)8:F6507F&'?./)>&FH=29C-DE3,=;343?!3='B(
@r8622
GCCANAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCTTTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTT
+
C2/<E#-78'"4A@+(460EAE6!')(#/:!<@?=);,.)7B#()+*:1#HEB1/%DF:.C+<"7</7"1$-<3,'9C,/E&%*#%;-E8&+3&-=%+<<&&>'44,#6>/3*+
@r8623
TTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGATGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAAT
+
?"@;#6*5%'A)/((11<83!G.&C&0*:(,,D4"&3?B8E8!8#G)8%B9:5153FAC14);+B?!H87%2(H02%*7;68D1F53,""BF=&G6?.249:('.;(:0*"@"CFGD=":-<&29F"-@9=%A5=/E:9>,-4&B<0C)G<'C?>!?!'3-C3),81BG#0D2,$@#G)2%-D-($?>C-+;E>;"C97>@93;
@r8624
ATCATTCGCCCTCCTGACAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCNTGCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTA
+
"+'&%%)++**(&!#'("(("%!!'!$$((#"'+*(#*"*'#&)#(%%(#%"(*!&!))*&+!$%$*##%%"(!"$"!"*%%%&"!)%*!(&%*&&#)!%(%#+*#'')+"&'*"%)+**#!"')'+$#"$)%*!!(!%+#!)&#&&"%)'!%(("$"'!&%$%%)')"%%
@r8625
TGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGNCTGCAA
+
H4;"9"7(=()"!,$3A@5/!@)D$/<5<#1-4,C5(&/FC'"A@.H;/H>2,H7F5@-C$#;5.9>H/$.;$&>+.7H/'
@r8626
ACGTTGTGANGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAANCTGAGCCATTGTTAAAACCTTCCATGTGATACGAGGGCGCGTAGTT
+
)"?(+C?4<!".F72990C23C-FB#4@E4,&F4C(=#;8=,+-&F/:/.)8=0-39C??"&D:DG;?DA&%7:!)#)@9%FE262!"/.,H3G77!<1-*H"A,&28)6+-)?E0C'AC6)@$<*B@54:.
@r8627
ACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGT
+
4!9GH-@!!0H@B$87.B+A<!G>3,/(6B*@(@;,(8$.0</.)'7BA0",:3$FA":?%3:?7*CE2-$$2H5?=-#F(+
@r8628
NTCGATGGCCATACGACCGGANCCTATCCAGTCGCAGTTCCCCCANGCACTGCGGGCTT
+
";7$<289-=BH3.*?+;)-3A:#(?*4535),'0";D6:0GE>#;'A$!$)H<BAF.!
@r8629
CACGTTTACGGTGGGCNATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGNGAAGTACCGTTATGAGCTGACGGACAGTGT
+
!84'><,D*+,>4A:E-#H6,C7F47(41;,87AD6*04+,:=F:-,54?E0'D40<33HA%G>+*B(''-42,7"8B6C-1=>CD'"&HA9$37+="4!<C$1(4.00"@'=93F-:0.3.>>6D
@r8630
AAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTAC
+
>>H2@=-,$D%0#4H*34?.G.&45@7C48)89*?!>:7,!/9A4'<7$.
@r8631
AGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGNTGGCTGGGAAGCTNGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGNATTTAAAGGTGATGCCAGCGATGCGCAGTTC
+
((&+")(!'(+++*%%*##%+*#(%%$#%!(("!"#!$%#$()$"()'$*(((%*#+&#)("+"!)%(!*%++()$%$!""")!&$$#*"#(&*($(!"+%'"!%&))%&$$+$%#"'(&!#""%%%'##)+'*"&*#%&*+$!!+&"$($)#%**")$)&&+
@r8632
AAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGG
+
@4-0D@!'11BG+!,C:6)?9/@.5$#6B9:$=&.@8<D17,@'?
@r8633
TNCGGNNCCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCANGAGTCCTGAAAGA
+
"!$'&)')*$+('#'%*'&))+#%+'+!%!+*")!!+"$'(+"#$*"%**"%#+*!('(#&'&%*
@r8634
GGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTC
+
&40EH.",:@-?D251F/5<-1#?=<9=<(.10EF';296>94>#E#"-<1E42%6&)*F0437961$.#2!,%8$@1#>'./;CF*;".3A/B/:>*5F9?;!5DH6=%A$'75!5F7GG?$;05'+."&#B?"#/,@-0;7<+$
@r8635
NCGAANNTCGNCANNNNNCCNNAANAANCTGAAACNNTGTNGCNNNTNANNNCGGGGCTNCTCNCNATGNNGATANNANNCNANNNCGNCNTTNCGTNGNNATNTTGNCNANTNTNTNNCNGNNNNNTNNNNGGANGANCANANNTNANGCANNNCNTNGGANACTNGANNNNNNGANNNANNNNAACGGATNGCNANAGNGNNNNAG
+
!#!"""$#$!!$##!!"!$#$!!"$$""#"!##$$!!$#!"#!"$#$!$!#"#"!#"$"!##$"$!#"!!#"!"!!!#$$!$#"$!$$!$##$!$#$""!"!$"$$""$$$!$"""$$"###!"###$"!"!$"#"""#$$!$$#!"!!!##"!""#"!#"""""#!$$"#$!"!#"!$#$"!#"#"""$#!!"$#!#"#"$!"!$""
@r8636
TNCNNATTTNNNNGNCTGCNTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGC
+
"!!"$"()'%"'$"%#$'"$)*%#"*"%+$)!'*)$*!%#!*"+%&&+))")"#)!'!(*#*"(&'%"+&%(*(*&+"""
@r8637
GGTTTTCATTNATGATGCGGGACCAGCCATCAACGCCCACCACCGG
+
4C-%E0:--6@&6G$4$9E8D4&F1=.,0(.9B-;2*"F;#HF<.=
@r8638
TATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGNTGAACTTCCGATAGTGCGGGTGTTGAATGATTTC
+
1>;H6@E".@-!FACH@C()4>9H8--DD,F"2+>%4(;,3(/A%.6!2=+3"%=H;=."(7A'A#9E9"6)?D@@&)E,>/%6E:"$$=.-)/+&:+?+-$"-.8.!(2DH>7."0:7:074'>+&=((G*>C>8)>
@r8639
GGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCNATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCT
+
C4/2%!&+<:&'"=,@D4#3@&*):EBD=:'61!--B@D8$731?,8(%2:1E&0"4?9+F@-@/H"/.42"A:@8C'%/CH6*86=FE$'F?+5*,G;B5!D!%?07;'+-+@
@r8640
ATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATG
+
B1:3E!B'D#=F6?#H%+&+<@;:=1?.%/>4!"=<D5$@D3:->0B5;2'%<H37?:3/#%511A84E)2H*@.F5@/$/AG<F!">D050>5=!''"E1@%-D8'71B?<"'!<>*9E9;
@r8641
TAATGGAGCAAAAGCGACGGGCAGGTAAAGNCGTGCATACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGANATACCGCNCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTNTGAAGCCATCTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGNGCGTTCTGCACTGACANATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTAC
+
&#E856@(F0*/-3.&2157>BG6>1?-:<'#(3992.DD74G:--EA$AD+3(7>72F4,)66BBF>E$*@A"G+27+F>)5@?0A0(5*!>0EF;&9=CG01F6/#!";**D4,?'8!##3@066@4D(#5E35$/=%+'B805/,(9H?350$+0+;?B?=%B*4,(8G42<<94A94/(5=&>,B,::#/%!418E+"GB3FE$$+=H<(#4H;)H;*%#B2*22":F'&E(8>CG<*F<;35DE'HF8@D:2)2AF.,9).%3'824!?%?)E7@;;+!B7>;9F<-*%&$.2?'5+(01B;867-#B>:#=9<B!H:D?2,E:!%"),27);C>6=3
@r8642
TANGGCGATAATCCGCTGGCGCTGAATTACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGATCGCCACGGA
+
'"!<:5=558!$A/&A-*?C%;285&-;.:>;8<.#;E&;A-'@-"'0@*&:0>66-$GD$0A#8%7.0("H9C?1A?+;H:"98?,",5!@DB@.=EEG:G"()##!"=":B;"=='H664428G%<8:2:C(%%>
@r8643
GTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATA
+
!A-B7<09;47(4=:%A26(8?G?,F@-/">'-D9%58?<%F+5#&GBG%E8H42G"2-71)4D"HA+@B,;G"/.-2B$CB-H;F>20&G.C?4'2@@C"0!3
@r8644
NTTCCGNGNNANNNGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCNTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCA
+
#((!&!"(!'&#$#&$+$%+#!&!'*&"**)*(+)!&%#++"&%(&(%)$%'%(%!$%'*"%""%%!+$+'$##'$$"*#&!)&*+%(#)*+!&"%%%*$")##**
@r8645
TTCTAACTTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGAGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATG
+
AF-!@1E/!-777B0"7HGF?=2+;5DE'2B9C*8A@!8)>7G)0%?-G3C1@3(E,)@<-$E9=?GBB-3<%7B10D77"!*A;"E:>,AF+3=<CB"6$H)#C3B!;):4)6+?A@0(;H!"?6-78%*<4-F;275:(/4',<0D2.@#=AF.%<2G?&*#2G,?H-&;$*-5GE:B'<1&>#@,#7+2%("4<""+>HA*10.-C@;,55H#>;)G4F<$(@.)11+A9G8$
@r8646
CGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAACCTGACTGAACTGACTCAGGTTGNCAGGGATTTNCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAAT
+
'?<F,'B&$F/)AE"B-#.4674HE!$D>)?A3.3;@6GC<-$2%E#,>9F'@FA4$1:=&8)E*A5H/'>:)7)&DDD948@H&.D38A/;)@0C-?<66))DF2""10D'>7HC8F+E&$<$@EE!/8!GHA39;/<&D<=C.&=.G:@*?%==4*E"C-1)#*F#608D?@/%E(G@)-A9;
@r8647
CAGCGGTGCGGCGCTGGGATATTACGTCNGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGANATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGNCAGACTCGCGGTGCAAATGNGTTTTANAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGANCACGCAGCTGCAGAGCGCCATTGGGAAGGCGATGTATGCCGCCACCATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGNT
+
0=7!!?*<B531=E>?C@%?;H#;G!$3+68;<E7>&(;&)/A5.&#$8,-!0$9D(0":$;"?&"-G*8("3,EA8!.))$?":,G=G3&C.BB"73?<10+$,:8D:8,>"-H3HB43,(@)$'+6C8!G/&G+?&32G)%+#"D)?:"+B,!#19353%$D4+6AE6*DG-!78#EHD&C*=-5774(=F%B,:4$CF>E,)D*G*,:8>@%HH>.:<"D.2G&/4H=C$18#2C.(A8D;F6B:,0GC#>906)&$1":8!G1A-&F'")#.B(*."G#F8#2?:DD:$0AA(#HFC4A;&H.#C;DH!DC(&D=?B+E26+;@4=E7:'/:CB<5D#
@r8648
GGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATG
+
8)'+)+(''8+;&&>H(?GA@//?AAH/;4B-F1+E@G9/
@r8649
NGATGGNTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAA
+
#CH/1$/>$1>5/-D+:24G-D/=D,$B(6H"7FBE-*<5?B8(@.(1
@r8650
AGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTAC
+
><-;CG(6"?G-?D/?5@;)="5-'8H'2-A,F=(GB5.442-?HG7+/=67EE%E>FB=/
@r8651
GTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTA
+
.6H66=2<)"@7,61,!'(@(<.F+3*CD('"+>;)58(?;?6H<8F501EG
@r8652
CGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAG
+
=2E@;+%9#*!G-+'.53'.14C*:FG';'HDB(7!?'&/()+18=$=.>A5<9-6A,?#<4=F(CAEG2!$0$7#2.'?5FFE-.:&'?04.7%@.D:2?:53
@r8653
AGCCCTGCCAGCGCCGNCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCG
+
=;2C!1,((-3%C594:,ED0%/0C?/?D-A#BD$@<14"H6,)FFA((("D3);D$),E)8+A/?5E1,8$)F?!8<;$+G7GH%F.&28=%B
@r8654
NATCTNACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCNCGGCAATCCGTACTTGATACCAGCCGTCGCTCAGTTTCTGACGAAACG
+
$***'$+%$+)+)#!+$#+!)&%(!'!'"*&)"%'')&&")!(%'!#*"'%"&"#'#%$"()+#+")+&+)*##))+$"')'')())%&!
@r8655
GCTGTACGCTGTCCAGATGTGAAAGGTCACACTGTCAGGTGGCTCAATCTCTTCACCGGATNACGAAAACCAGAGAATGCCATCACGGGTCC
+
H):98<G*(.H)+/$:?$<#,(<<<GE-6>F:C85<=*9%<!3)+G#6+6A??<:*$;%E7:<98?0481CE.!HHB/.<!-EF2*9&B40$
@r8656
GGACTGGCTGATGAACTTGTTAGCAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAGGGCGAATGACCAAAGAGACTCAATCA
+
$6+9*)4&78$3%CD@D!'#BB+<*40DE$G@B:4H$;5!A.G-:?A!G29?D>BD8=4DG7HCD)+E99?A!)727044<!-G;7616:6F(:G2='/4*-)7$+G',%A"3*
@r8657
TAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTCTATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGA
+
&E/96*B"&33$:*:0%H&:=?)-(2;?0@?C@"%6H@&6D=&66=?$!1?5A9;'H<2&)(/,.E%)#:.!@?*E,-';<@73A94D14A=*E#D;?6952:B)*,(5%8:?9;%A
@r8658
TGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAG
+
C:8-F139/)5.+<C>+,2$9?()-=F."%/!H9"'5%;,B2.BE4-!*:@4E
@r8659
ACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAA
+
/C2$-A(:H"?HA10A381F3H6)76,C0EBF><$@2#3#C!/($/3/G98HE;:7;'&<,>8%.=<(#7%+G871>6C9/>>.&1<C.435B-5@!+C-6-'(
@r8660
CCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTACTTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGNTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGC
+
GD1<<.G?=A&4A(;=<H4:0/*>.9&&.;.0*25E:;;A(;,D3=.#*-H)$*6%01>)E4:&DC%$1@!*E"9B:25+GF/1--D.(.F,4.;<&EC8>>!A+B+5G6"6D2C&=5F/6'+*41G6/;BE$93>"48+E:0*'-2F..G+?%),!;$D:$H?
@r8661
CCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGT
+
99DA8<74&?1&HE(@:&%2>AE;829'4?*+''8<)3#!!B0D?1>@8"41',94.B7;DB4364,;G.6!1?4:1,>0
@r8662
AGNATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCNGCTCAATCT
+
%)&)+)'&(*#&!((!"$)'+#$%$$')%##($&""'''#+!+%'$("$%$$!
@r8663
NNCCGCTNNTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAA
+
"&*$&$$%#+%##*&++#%($$%(!"#'+#'"#+)(*%%""!+('$$'&&"('&(&%*!*%#
@r8664
AGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATAC
+
%.C;3+-=A1/:<">AFC8*227H6;05@?!$4BF,"&A:8!!+&17-5+
@r8665
GCGGTTNGTANGCACGTCCGGGTTAACGGCGCAGTTACATCAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGT
+
$'''""%&#'!+!"$(**''$%')+***++#*$!$'%))(%#(*!)%&)(+!#!!!$*$!$!((!*%"!'$)$%+(!*")#*'%"'$'%%!'*&'%%*''""#
@r8666
AGATGGTCTTGGGGCGACATTGTCATCATATGCAGGNACCATGATTGCAATCCTGATTGCNGCCTTGACGTTTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACA
+
;?48DE"1>*?.HA%!?;CED+.%,HE.F157#7C"8G$5=/F1AB&>6#??:*=G3@FC$F/@!<'.&G81E)C@79H6G:)GBFD'F)'9'55,F=.@6!'(F@"09?1:*
@r8667
GGGTCAGTANGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGC
+
##$$(+***$&)#!+(&($!&#(((&(%*+!"!*&$$(%#%*"*&##*$*%()"'"(*%
@r8668
CGGTGGAGGCAGACGTGGCGGCTGATNGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGT
+
0,=2A8"*+/F/$!0@%>@D9G6GG$(+HG9;%.)H&&H19>50HD+"2/8!<*F*E!%:<$>3>6+E1BDG;"0=$G!
@r8669
TNTGGATCATAGCTGGCAANTAATTCAGTCCAGTAAATAGCCTCAATAGGGAANAATATATGCTTTCCATTCCATCGGGGAAAAGTTTT
+
7)A!E@+G7/H2#:>@&#1:0B?=$&(G*!>*9&?.7:7/@*<CB--#FB7"3B986!##2%#H(+@3@+3957F.0EE2+E5>8:;8-
@r8670
CATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACNAGGTTGATATTGATCCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCA
+
@(91.(G@/02&41337(*53(&'$9%/4.9-0;)9:)G>*?6603F'E+A;-EG?0D1,3A?"0)0;4!5#,D)/5D>D@=5D'(#B0C/'5%,?B#+4E&(A$H';C24+%'+G%(*7/,7@51EF))11;/6/;EB11AF9(!%A0DG$288H$>45-@8<BE79;.87
@r8671
GGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTA
+
C9"3#:5-.D<?8/H;2&1>1:*.C>)/#FAG6@ED(D9.3D'%,<G74.:8<%@D1<6,&&9""0-!=-+H(8B%>!*27+>#(;CHF*=E5?='D9'20A7*H2'H$2:>C3!#(6>*.;F=7H*BA=C&1H89902D/'D
@r8672
AAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGNGTGTGAGCACTGCTGCGCAGAACTGATGAGC
+
+0$92.(E%!H:/#)FE8<,:@C04:1.,/.(8H5D@$G:;461,+6&8%>99A@3.@$&D@#3H$A.'2.0<H(3967/72@)D&?;,5E,)18-;
@r8673
NGTTGACGTANGCTNCGGNCTNTNCATTCAGCGNATTCAGTGCGTCAGGTGACGCGTNACATCTGCAATCGCGGCCAGTACAAAAGC
+
"')("!*)*'$*&(''')&''#*!+)%)&&")(!)+""&)&"%+)*%)!)#&)&%$$+(&#$&*&$&)"*"+!$+"$"*!)*%'"(#
@r8674
ATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGG
+
E?1*'2%(*,A!==8B<(&*H/-3C-,8E(#&"C>DA268'G,52&8-@-7"DA<""9
@r8675
AACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGAN
+
E9,>-DH<'--DG--'),%G)D%$=;9B&1'"'0)'"@-.9&>F0,!2$*$1<DB>'BA!F2C;B&H(!C5>-,'6D5CG:20(%?@"/..+/<6
@r8676
GTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAA
+
A,'$)C?!$+G.#&9=0(!@4/?(49'3.2(&A/B4@=61;9+')C.+#117,2*H1.+G.HECD$;::-.:>:44"+9
@r8677
TGCNNNNCNCAAAACTCAAATNNNCAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGANGCCTACCGCNAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGNGCGTGGCGCTTTACCTATGATTGATCGTG
+
"*('!!!$&$)!"(**#$*'%"&"+'("&!$*)%*')"#'!'(%*)%#(#)'!*##)#+)!$"#&!%#%()&++")&"'#("+!)'+$$!'()#&+!&#%%)$$(*$)(*&%"!$$"%$"&'&'&'"+%''+++))&"')%%"+)&"('*+*$!+!%($*($&##!")"+"
@r8678
ACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTG
+
=.!-A9:<A3*:?>!3)))**7;-(#C*2DG,7B"@8$(=E!D/<52..':$;*=%6"?#>9F1:+/G7$G50;H<,!."
@r8679
GAGCCTGTTGNTGGGTCATGGAATTACCNTCAACCTCAAGCCAG
+
52>'C!9'/C>D')#)6+?D'%%*FB9>3=:$C;5*33F,;.*;
@r8680
NACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTC
+
+,:1-@.CH>F$=:9'-@%/-##3#<2%'"<:?73=8-!@
@r8681
ATAAAACATCCCTCAAATTGGGGGATTGCCATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACC
+
$"B#3#7DE49#-G7E11(H"-(+1>$5)=1=4;(4=,(-F9&=H;%(0B0$/93A*EB;0D?H=28A;'8&E;!:%$&E:&23D/A-/-&=E#15*#(:-G,DB)@25:3/H#@D?10'$<9
@r8682
GCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCG
+
:<E&E*HH8G34/#8"):+7<"9H?$03D*@8+F;/)5#;+45D2.%!&#3.<228>3'?!9#D#(:>!B8=72:-?.E5-=%<:#C<=@5C=<
@r8683
CCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTANCG
+
2'4,?%,D:+)GE,8*1:,F.B,5*"'=2A@6A(::?*A'<A6<2):2>/&08F?472%F2,:?!!!$9#H7&;F?8;<FB"6"0('&%4'7,90//+':03G">536>98-;
@r8684
ATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACT
+
2"01#?->H/;A69<)!0$20A5DH7>0G*0>)+3C*<F-:9:E1"(42)024/;+18H-HC#@A;H&9
@r8685
NCGATGNNGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGNCACTGTGGGTGTGCGACTTAATTCCATCCT
+
!"&&$)'+"+'*(%$&&"%(##"$%(!%+$*&"$#!&(*!%++"!"$(#&!'*$&"+%)"!#*!'!+("#!)'$%
@r8686
GAACGTCTTCCGAAAGAGCTGGGNTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCAATGAAACATACTGAACTCGGTGCAGCCGTACTGGATGTACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCNG
+
&%+'&('%)+'%*)%++$'!)%)&!#$"!#&&%*%"'%$&'!(('&(*##(*)&"%)$#))#+%+$#**'+$(+('"%"!((!#+!*%"*+%!+##!(!+%""$#!+!&*'+*&%$$$**)"(!$%%(!)'+"*!%'#!+"""+)#+)$(!%('(#(**!"$!#%&!&($!(!&
@r8687
TTCATGNCACNAACACACGCCNCTGACAGCGAGCATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAA
+
#)(&#*!#)'%'+$&&%"+")'(*&)"$#%%(#*""%!+()%#**"")!""'"#'+#*###%"!(+'('"+&$"'#"&!(+%%$)"!(
@r8688
NNGCAGCTGCCGCACCTCATCAGTCNGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTG
+
%$#)+++'+)(&*#&'&"&)*#&&&#**+('+&*$)#)"+&*%$##$$$+&"%"#+'%()+%(&$+*+#%%$*$'&*(%)&#+#)+##&%+*+%#!*"!$+(%+'&#%#!'*#!$+"%(*&&)&(&+(!
@r8689
CTTTCAGGGATGAACGNTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTT
+
F?18(60$0A5>4H),B#,"9%)-7E-*E$B4$:A7,7@6,D&,,30ED()-'1A/3-0$FGA-BA028G"9",H%D?;4=9=""#+$1!F$F=1H$:-,@-0
@r8690
TGTTGTCCGTAGCAGGAAGTTCTTTNTGACGCCGTTTTCCACGTACTGTC
+
5%(A.6.D5C<H/$"=;C*.+AH@,5.$$G)=3:"1:AHB44;9-E6C7F
@r8691
TCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTT
+
49?A-B./E'7:.5;8<'2:%*H:7A=4:#(A=!1&#+&7&7)B0H.<$@:&:D#@+7+D?:+,>?A)0'+72-8-H?GH%1!>6E"97@.2F
@r8692
AGTGACGGCTGCATACTAACCGCTTCATACANCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATT
+
()+4?D1EC4F&6-'D:C,"$?%!FGA&=&;11C+52D$G13H*<9)>D(-H76G5#;2@C%+%1/=
@r8693
NTNNNNGCAGAAATGGTCGATTCTGCNGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATACCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACC
+
!)!$"$"%'&$')(&%*+#%!*(%$()%'&&#)"*+(&"%"(#!("+'"%*%!%"!!'+)#&'&%%#")%!+#)+#+'!$&"'#!*(((%!%$("%)*%)&*"$%+#+%%#(!$+*(&))$"$#$**)%'+$()&)*((#+()#%)&+***&(+"+"&'$!*"*&(*+%"#(*$+)$($#()'(
@r8694
TTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGANGGCGCGTAGTTTGCATTATCGTTTTTATCG
+
G5+)6)$C23:0>A@F5G!&55F0#&$;6#H)#B8!430<943&8<<?7F#.*G<20*8EF:(5G#0DC3%*'-DHDH37"B%
@r8695
NCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTG
+
.-(5",(4G@>!GF+<C&)A).&E4D73)$2<E,#84":&HGD?",=455G#3C+G,9&D!28@%*51%,((F#&3.?E7#@"1E0*=;B/C?+12FA8CD0)5F)"@&,-BH585%8.)DG"/:%H/;472@:(!+B/"70%19.-6?8/H7*<%)CG3B2#A,;@491-0F@.A6(C%1?4,@&1BGFB:3"8?
@r8696
GAATGGNTCTCCATTCCATTCTCCTGTGACTCGGNAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGC
+
0,@(+%HA19.F=C%8)$C<+>&".!@,,8"=D79#.D(38'@>(2#0C4.&+)-+2?CG99-3*E%7,E13!7$
@r8697
NAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCCCGCAAGAGGTAAAATA
+
%6C.>G%3#7#A5#+$00+#>#$%G/($5";#F3@::731%AGCA#,-G$984HD?F"!67%47:A#0*D:<F410G#D
@r8698
GGGGCANNGAGTGGACCAAGCGTGACAAGTCCACGTATGACCCGACCGA
+
#$%*"'"$*+&%'+&$*+#'+%)!$'!$$"#)($+$'&#(*!#+)&(!&
@r8699
TCCTTTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCNCCCACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAG
+
%E1*@6/:G>"5&-C!:2D!)0$##99"+?>-8*@;%4,+(*#<48<F-3=F6>,1-'&#?5D409?4A);7"=!)/-.24,6"&29H;!?C/=7:<12!.6G1;080G.H5.;+"*44<D;7!?)216F#!E5,*;
@r8700
TTACTGTGAGCCATCATGACGCCGATGGAGTCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTNCATGTCGTTGGCAAGCGCCCAAACCGGTTTTANGTCACGCAC
+
4&8G6G?"?2@8H8,'#$(E9/3B"0E45$1:)@(>(E#6?&:'.642$E=;2&)"#6AH.);F==H&B,3'0@+.05D.**D($:8>@.GB$1BCB$&+13"$!;'54;H08%C6&$>2/H"B)6#*6(1&A9A4!':DAH3
@r8701
TTGACGGCTTTGAAGNAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACC
+
'89)$1*+:@D<";7'!<@&5+4+@6E3;B6G<9!A/)*45DG0H%!0:@6!:(;;@8?7@2+
@r8702
AAACCCGCGAGGTCGCCGCCCATCCGTCGGAAGTCCGCCTGNTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCATTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCANGATNACGCCGG
+
+"&(%!&!&'$'&$*%)%))"$*$#*!%)#!##)"*'!&')%)#!(!()*&)'&)&#)))%$#(%"*#!&)"""+"&#+$)"*#$*$%&'"!*%+!*+'%%*()$%&*('$%'*$'*'$"#&&#$&&!$!%#'!%&#((%(%"*%%"%&"$+%&$##'"+*#($**!%'+*&&)'(*#&!&$%!*&"&'
@r8703
CCTGTTTNGTTACNAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGNTG
+
((+%!(##+&"'%+%!$+*!+%#&&*'$$*!&++)!+$$')$)'+"($"+)$(*%!*%!((*&')!!'+#$+$&$'#%(#$(()"'*+)$+$#*"$(+(%&'#"+($#%!*!#")"#+
@r8704
TAGACCTTTCTCTCCCATATTTCAGTCGCGGCACGATGGAACTAAATT
+
%!+$")''")##%&!))*"*#$+)%+)(%*!*!""!*$$))#%'*)''
@r8705
CCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCNA
+
F&40(#E(-:+.2.2-/.<!?-?>&5/>;,-*?"8D.&%>>
@r8706
GANNCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTNCTATCTACTCTCATACAACCAATAAATGCNGAAATGAATTCTAAGCGGA
+
$&$")(+)#!*!"%$!($"&(+!%(%*("&##!'$!&!&&""$*$'%!)&$$#(#&!+*!+""!+)%$)+$$$%!"%'(&"!*#+'*"*''(#*#$!&)%+$&#+&+$$("!'#'%#"$%"$%'#%)($'#)&'+!*%)*($++(##&%+&#$$(""+*$"!++&%%*!*'
@r8707
GCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGNCTTGGTGCGGNNGA
+
-869CD2F*6&1.;)=3*49D9)(1.!4;D54E?>.@F7AB6?+*H%@:(H#7G/F:5AA+4.;82/+?&/DH4F0'G$
@r8708
GCAGTAGNAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATANCGGAAATGTTAAAATT
+
"E3(-@?B&%/&?>0A#>319#H5B//1@,82-A4$(:(+:>"%65%#D'EA>/>B2:-1E>";<1->B+=(&#?<@E>+(:?6F%&F)=C:G-7$A#2HA!G$)1ABD+?!5227A;.:H@G0-;
@r8709
CACTATCGGAAGTTCACCAGCCAGCNGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTCA
+
+**)%('#(%!)))%)#+!+&$%+$'(+%"())""*"&$"(*!*)''$)'%'(%+$!#%#$"$#!*"*')'*+&%&'""#('!&!*+)&
@r8710
NCNTNTNCNNGTTGCCTGCCCGCANTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATNGACGCCGGATGACCCCTCCAGCGNGTTTTATC
+
*'$'!*!'*$+#)$&"**&!!)(!""!)'(&$#)**'"&)'"#&')((&$%''+'!*'(&%#((&&%!&+''&'&)%%+!%#!%*"+')))*(%)!")('&$#$)*%&"*&"%+*+
@r8711
CATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCT
+
DGE7$:1;+9&-B@B"<+H.?37@.D54($8!%(F:'*$!G:9C4*%DC8)E
@r8712
GCAGNCAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATC
+
4&B5!C3#G8<$?A:25.=,%9@7A6:1!%G#-.434?'A<C/A>8!>0)4(/(;%6C92(0D2:C40DA'9</9G8#);6,&C)5:<B%%;598)";?58('1')#>/@!6F*9<HHB5;#C*:$3/GB9?:(<E2HFB87)+<B/1:/5+!H;A7>5>-GH'<!$=%3./!83,7F>+39&=:@3!H971,EC##:&"<+34=)E9G3)%;/7F/@HA*3/G6,D#3(<(;E=%AEC)?">;.G.8
@r8713
GCAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCNGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGATGTCGAACAGGGGGATGATGCGTGGCACAAATTACGACTCGGCGTCATCACCGCTTCAGAACTTCACAACGTGATAGCAAAACCCCGCTCCGGA
+
*B"62,3)$@9B2FH43+48F$F@$-G'(7(3@0!%!5C1#6$<<!#4,9/>,=AHH)-75+)-F/F/9$D'#>5=93C=:=:E515DF&0=(F<8$665'<+,("89FC(>*!#8.AC.3,9E(-A1$?(H6(A1,+&'&G<&4@D(>2!D.9G9<0A,4;G+C"19@*A"7&<D1$<&$C,:)=#.'H0767#-D.
@r8714
ACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCTCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATG
+
)>8.*/)E+%8:=!&4D6#,24H%-+@#"AFG@G@#?0<0E9H<G$;=D8:&7%?.4A0G$612;<3>:41052.>80@76,63A;G
@r8715
AAAGAAACAGTAAGATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCACTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATG
+
AE>E&.?33C7.E#D&#=%16&'9C=HF$6%.C>ABA!2<$@C;GB*+D*"%GF5/C5F-%==,H670G!C>#)?A#86G5$18B>7=*2#"AD.3?!F$7GH5#7E-'HC$02!5-A6,!F(=D.6386,1(8."+?EA8:$96%
@r8716
GCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTG
+
(=;$E$B@D7G)"2$94/?6).+@!),C+4)751;$C=:!?=>E>!+("G#DBH"4)!"'
@r8717
CGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAG
+
6279'*=,D"3*CF&)?G.?FCH5$G#E>-%0-F$?-?5FB2B&#3#H(4#:B+869)1
@r8718
AACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATNCCCTAAATCGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTNTCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGNAAAAAGAAAAGATTATTCGTCAGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAANCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGG
+
1<9?A<HH34C0>6CA2A:0*1-A8)6B:/?4353<#B;B19A.-?&31"1?>>"D,5F;4#9*9<>?9A@=%@:/8-),2?;?%2%)>+:';4,%H9;D2+*"3*>>#"%*<DF=A5C$22!6"2H'970-&@3F10@>>'!.,*?2!!8+E:/E@!4((B5D<35?H3CH:"HHH96G2+1'#66,$%1+63'54<$'5$-9.-5;G2AE1,6>#68<,1<B/)@.378AB$7%.G.9$"&
@r8719
CNACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGG
+
*$3G:C=GE-59?GH'@EH6?A@@B8,%B>86BC@F12H;;-B;++G>BH@85/-<B1CFB@*C..>':7H''/":B@E/!&('16&E>9(;,3+E@%?515()5D8;(!4&/04G'>8'!;:"GBB
@r8720
NGAGNCATAAACCCGTTTCNCNGAGTCTNGCAGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGTGGTGGTGACTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCCGCGGCAACATCATCACGCAGAGCA
+
!""%##&*'(#"('*)'&!!"'&%%$#&!$+%*(+"*!'+$##&!$%%)+($&"*(#)!+'**$'"%"&'"'#$(+*'*&$)$(+&%'%$&$&''$*("(%)#!&"*'$)()""'*&)**&$'%"#'++)+!)')'!$(%#)+(%&$&
@r8721
NACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCT
+
"=#AB*B+3B:7FB;4!F&CB,F$-)0@&5FA@!69&EHAA+6./13</<-9*#6;
@r8722
GCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTGTGCCAGAA
+
5?,!"5'AF6'3-2)7G',/G&)8H(6:%":<1$3*5+9A@"F$.1FB&:-=H#/'4#!1@4DB?.,8<!BE:H'H
@r8723
NGGGTCGCCCCATCTCACGCGCCAGNTTCAGGGCAAAACTCAGCTAACCGTCGAACACTTTCCCGCTGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCAC
+
$(C*@C%2(9..$%0C6<A8@+:=?+G1E?74</DA@',:29DH*F):0(1*4<?:))0@D.<(?2891)#5%($1&1%C#G)&@!3-/)9".51F<D,!<1%=7B+4F2<>:<A/&2(4
@r8724
NNAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTC
+
*'%"+'*"+"(&+#'"!)!%&'*(!!&)$)&%&#(%$"++)&*!"*"$
@r8725
GTGGGACCTTTCACATCTGGACAGCGTACAGCCCGTTCACNACCTGGGTGCAGATTGTCAAAGANTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTCGGAGGCGAAAATTGGCGAACGTCCGGATGCTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCG
+
9B87HE2>0?3%E$%1)B/$(%5>&=G>(-%/$4.9<7=,02,6$=D2DC8((+9"7;H$)/;555!86G;&09AB@==?&5@5>3?+'3">))458F/6>='>;9&9!5GH3<<A,D*$/*8*19=#/9'B5&@)87+-@'1'5<</H*,0/4%':0:*,/<;?9#6:'D<9!7&:;D758'0E8(<F%H1.2-<476"
@r8726
TGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAGTAGT
+
9B4HA%+@#4#7D+9E3(/99$'C=F@!)BED>&1>D596>+,@>G)E=8EB"G58<B*7H1;1H2>A7"%$?<%6'5"#:$,*.1!?A5.H442'6A-HAF8B(@51>(5<'
@r8727
TCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGC
+
2FE<)!@-&%3E<7?G#9F.CH496(,#3DE.%;"<C)5>G3"9+/;#+/2#>:7:8?G('3?"B&.E@":D!F?=+H,1<2H/;,F60D+!"!
@r8728
TGATATACGCCGAGATCTTTAGCTGTCTTGGNTTGCCCAAAGCGCA
+
CAE*"D4?#A0)?G9F3E=6(4<(=7"17824C4<<#/=%'B2E!)
@r8729
CAGTATCTTAAATTTGGCGACAAAGAGACNCCGTTTGGCCTCAAATGGACGCAGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCNGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTNGTCATCCGGTGAAGAGATTGAGCCACCTGACAGTGTGACCTTTCACATCTGGANAGCGTACAGCCC
+
:?&%BG!0FEF:;'&?<*!2DG7$3+F.8;!D/+H<4:A?CC4(/')26'?GF=D=&;:40/G8;</,"0F:F$AC%,34=+/*GB#-.;E=3"H+F0+>4H)5D'@"/'/%'7*B03CG:<$$6/F!@55=5/6$2"-:CF?+=A89,<37$7A6"D><D%8"D7?(=CED5&+3G)7'1+00<..)F!-<=)G%DC!4C9CGG>$+D%DB5..9#B8C(G:96=1BDC!<E;09".(7/CB1GG)C=?8=,@H#,
@r8730
CCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGG
+
@BH7G<EA>;,-64)A5=7++++8H?*"<+;%&'<58#,4=>95'37;6>.F%!C%8<=B-
@r8731
CNAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCT
+
*&HF$5*C*@<+G#:;5H;3:%8&>74A@%,&'%.0==;F5&410F'>D&!#%)###/:GF*/*CAA;G4BH,'DE5;;19
@r8732
GATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCA
+
E$.@4?.;;H+%/@A-?'E9DH65%%6.:9"&)=3"/**8*%28<=+>/44G3<A=/2:=
@r8733
CGGAGGTGATGCGTCGNCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAG
+
&""%#&$'#(&(%'#)%"$)++*!%$#+$*&*#'&%##)&*##)"*'#*#')*'+)+')"%'')(#$$"'%()*""''
@r8734
AGNANTTTNNANNGTANCCNTNTNCAGTAANNNNANNNCNNNTNCTGNTNCCAGNANNNTNNNNNNCGTNCGCCNGNNC
+
$#$!!$#"!!$#"$$$!!$$"""!!!!#"$$#"#$$#"$!#$$!!#$!!##$#!"###"!!#!"!##$#$!$##"$!#$
@r8735
GNANTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGGCAGCATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACNGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTNATCGCTACGAAAAAATCCTGNCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATNAGCAAAATTAA
+
&%"!+("&#')'(+!()&+$('(%+"&%!'+!$""$*"%+!%*(!!)(#)*(*$!"#$))''#$(&)$)"$%$&##&('+'$")!'&%!&&&""&%"&+$*++')!&*'%&&&!*+$'((#%"$)$)$!$*)&&*+$(!)*#*)&'")*&!!#'""(%#*'(*)(*)"+#*#((+%(#$#)+!%'+&'&!*)&(*""**#''"))#'!$
@r8736
CCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGTCAGCCGCTGTGGTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCA
+
.$)G+ADG;=65A"$"7<:;8@..!-FG"@!<%82915;>C+F<"89!B!DG#D6086&(;?.'<!.(4+#D$-/2(.4(955A!-4&:AF/B6/&.8E6:&4.51@1B.4*8!6<D7)";#9)<4/&;&&D#GB1;#.0)@14689=684#((
@r8737
TGACGTCCTGCCACCGNAGAAACTAACGACATTTATCATGCAGCCCT
+
&'/7@E?1:H9E':$&7;680+/D5+%&>=#AFGC$D:2:*@4+51.
@r8738
GCTTATGCTCTATAAAGTAGGCCTAAGCACCCAGCAGCATTTTGGAATAACCNACACGGGCAGACTTGAC
+
'+)+!*"!$*(*$+%%&**%#"+%**$%"#&!!%"'%&%)#!!+$$)%*!#%$+)"$&*'%($%%)*+%'
@r8739
GATCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACA
+
*!73<5HF7"3B:</??68'G#=<6>6!.F%A!)?9%.#-=#9!:.0
@r8740
ACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTAATCCGATCACCCTCGCAAACTT
+
EB%H9'%/,C(//9D!-++6BC(9)-$HA&1+0H19<H;E")!;&8FE0H6'-#4A.E>;C925B+BF@2>DB0*;'GB%)/"HA<"0HG.DD60A
@r8741
TCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTATTTGGCGATATATTAAAGGTCTTAGGG
+
%BA.?&*:3.?$4:B!5*6,:#@/:C7"F:24)0%)G"D'"HA34"</6<7D#<<>$)"/<*"B@.G:.3)<>&D-7!%>9=E%)*-A/A/)E-:#!"15>%A=2A'B9)>1))F,7@H3F#(3--A5E'A4?06B:"/9@&6@9%0;,&GC5!G#D,+;(BD'8#B@&)<.>/;':@?23
@r8742
NNCTCNCNCANANTGNAACNCCCAGNTGCNACNNGATTCTC
+
%#*$%$!!%(!!"#"&$*%"*%$%!!&!)"*&*$++!*$('
@r8743
ANTTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAA
+
*!C%1B7*/1,;#<C4G;//0+2=G/A>6,#:8*2-<*/G
@r8744
GCCTGACGNCNNCNNNNCNNNNTNNNAAAGATCGNNTGNNGATCNNTTAAGNGNGNCGCANNNTNANCGNACACA
+
""##$"#!"!"!!!!"!!""$$!##!$#$##!"#$$""#$!"$$#!##"$!#"!#"##$##""#"!#"$!#$"$"
@r8745
GTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAANTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATT
+
75&C)H.97"A>9$@#E+#8C7H:2A;!B="D%.>050:2$44.3:)F2>%F:@8DAC<:A+6#372#6000@9?&.%/26HG"465HH>7/<>:";GC)6=000)5@%*)$AA#/+*=D=D>)9?
@r8746
TACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATNATCTGCCGGTCA
+
")1*C&B&+@#6A1)9A%17#7*G4)&BHD3.B629$7AEG@:2$+#"$B?+3D>
@r8747
TTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCCATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGAAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGCGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGT
+
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
@r8748
TTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCANTCTAAAAAATNATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAANCTACCTCTTACAGCGAGAACTTATAGCGAGATGCTTAATAAATGCTCGCAAGGTATGATGCAGATAAATGTTAGAAATAATT
+
080=?/;5@8/(.,*"G-C"06)?4+;FHH3+-;F9<$&7/!>%0!C7@-4,5%'575A3H<+@DH-$;@+$GH;10'A(.#;108*E#*-*0>'FC7H4+2>D3;HD%!C$6)DC'$$'42D#)?D<*'+731$#:#7)F&C$E<-91!F;?#!CBFG$$;H/1!H0;=AC(=H=C=;?:#<($E9E1"!F@74/,&$?00(2)5#/,?5%)"BF0*;
@r8749
TCCNGCAGTTGCCGTTTATCNCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGNCAGGCGGAGNTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGC
+
<C)&-4"@(6!&'%::4-940&.-%,/+G#&A#-&H2@:,'GA?/+298=E8'1?<&9E%:A4=0@935%5"#72%#*</%$'/0%.1&H2D1(C(%>%7?<9BF,(H-,
@r8750
CGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCAT
+
/>@270B!,BD6+@A',>2%+F;$$"AD63'/1)5C5A'&'%F@7:@B845%H$'-7;-7B&0
@r8751
GATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGCCAGAGCCAACACGCAGTCTGTCACTGTCAGG
+
:C="53,"3*#D#0/&?+G@;?2B"5$A""/<*0;"=3E;9.CF$F&4/@/'@0-8>AC210+@,+7*C'4>A4#&?>@#8"<?!67.0G>44G'%4*2")2=?@*."6+
@r8752
GGAATCTGCGGAAGGATNATTATTTTGTTAACGATGAAGCGCGGGCGCGTTCCTGGGATGATCGTGAAAAGGCCCGTCTTNCGCTTGAA
+
0$!8$&9:.06B2&.5!D&;D<'/"50+H>+<@=>'<9>6608!BA3<4?&-F>9=@H43>H8"/F+5#$-6(0%:?$;7)$337.<G#
@r8753
TNNGCCGCNANTACNATGANGCAGACAGAATCAGCGATTCTGGCGCACGCCCGGCGATGTGCGCCNGCGGAGTCGTGCGGCTTCGTGGTAAGCATGCCGGAGGGGNAAAGATGTTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATNGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCC
+
("!((%&($()()%#&)*&%"%+!&"#)()''+%'##%)))'%)#&+*!!$)"$"'!()#')$"&$%+"&)&))*#(&%($&&(*!'"!'+!&"&%!&$$!$!!+')$(#('%"%"+)(+#+'++#$+&++%%+%'*'(%$))!$&*")'!(%+""'&&+#"$)!++)&$("*'""*+)()%'!(+'+""*!#''))'"#+&)'!(#()&#*%(%$!!#"&*')$$")!')+'*$*&+
@r8754
CAGNCNGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGNCGGCTCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGANGGAAAGCTGGCCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCG
+
&('!%'+$#+""#&!$#+!$$$)#)#$(%#((*'"*+('(''+#+"("$$('!"'!(!!%"%)(+%&!"%+*$"*+&((%$*%(*'$'""$*)$*(#%*"''*%#+'%(%)%"+('$)+""(+")#%$"&()!$++*'($+(+&(''#*("#&$!'""$&**'$!"!!#!'%#%+((')#))()$)""%
@r8755
CTTAAAGANGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAANGTCATCGTCGTTTTTATCC
+
F+@H!,C&1.2-5<87-HB5$51>:F:%)C%!).A5%F9(++9=9.-H+606"2<C:;C9?F+2685@#-/:;+;%=A.-"4.=,B&8+,@@72$:<H(5.3,+$A,'#?)950H?*8.6.1&:
@r8756
GTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTG
+
+1;:.'C.$2&B#%%5C)H!+.1G&#2#ED1F:!"GE!<914EB<=-3C@-6;+='?
@r8757
GTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAA
+
6*@4=(HH:@E==&7C%+8=0C&=;?=G<11$$,9E$@FB+33H$4,"+9/G+H>6?;>4$3E8D)!A*G&5G4,>;
@r8758
TCCGCTGGAAAGTGAAANCCGGTATGGATGTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAA
+
9-C<A8!;<*!4'$<E<B3@&=''&!,+-<;4>5$3>=#+--5G"(<?1')%<#.-+9>*B!1&%E40#487=2/+2-C)?G;:E7$6F5):?'5!<-"%H'+7'C!6,
@r8759
AGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCA
+
*HH/*;&#%+;2F"571=AH%>2A421+?'A#-$2D%;.3,,2!<$6/@H,>E;D%A;1$%*'>H84
@r8760
CGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACG
+
)-F6B+8>=4D4!@2.,G<;)@4HADH3.!&?&ED&##68;',@)<96(:"2F'//(F<1,FH>%5-4:
@r8761
CCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGNATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATGGTGGCGGCATACATCGCCTTCCCAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGCCCGTCCTCCACGGGTTCAAAAANGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCAT
+
7$%$72969$%+/D)$B%6?!:,(=#:8+$C##5H$!;65&9C"5<;45C",&)D/6A83DH,46(*?&,,8"7#C/18*2.)HB6FBF?EH@#&BH!HE@@8+1@4=*=,"87E2%23,>+$E((@+"2?!.13+F.7+?G">+9@#FB=6687591<>?6=H&!)E)>))3CE)85"DFF+=%;>.D@@'!,!/46D(/#GA+.;#$8/B7:6.&,&'F%&1)=81-BA"F>8A?00B@(E+<,C"3#86D2:$"8%?4F9,A(B2'),C3@&(80+BD5BFB/!//F*>EC6";(H%'',>65::+?;:,#H2$,H2%C!/#@G7,G,#
@r8762
GTTTTAGTTCATCAGTGNCGAATCACGCCGNAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACANATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTTGTGTGAAAACGGGGGCNGAAGCCATCCGGGCNCTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATN
+
+H4"8*@!)9&?0@G@+402E1F5000)/17B@@),%7:9.''&C+6+68:24*DDCA9,+#@E!)?A,F4$7903<"E9G?H073B+:,D.*>>4*78+-,E*@C';G$EGGHAD2@%DG&D/64D:>B:C!H@$+,5?B&:'.67!45"$DHFH<@!!#:&7C11?)7F'1*C<:C56'-"E&6-(+GG;500H>+14;63(4-7'B"70A@6@$,A;@HH9,>>)F+*8$F=%<#A5H29"D=F@$4E>-;08?)7'F1-3*A116F:F0*GB,%/@&&(HD)>40G);,;B@F@C6=&850B01&(-0=C21B+@CED';,1&7!0=F*E#,E0'!1?%;#,G)H,7/%;(6D"9
@r8763
GGCCTTTTTAGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCTAGCACATCAGCAAAACGCTATTCACGCAGTACATCAAATCCTTCCAGA
+
&E0A7D+!'D+8B377,'G9+;D>@3<4G(.+6/"+<&2!1%%F%EB:#3;/+GH0<?1DGF:>>-F5-19;%3"8G@G%($@AAC"@/A'%39)@HD0C<7'A
@r8764
ACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTC
+
:$7/3$%2@,+G5%?>43=%3?$3BA?H5'D&@9A:@!E$@2"@7(-?'"$#$$%B)+)8?3213,-,"5
@r8765
TGTTGAGTCTGCTGNTCAGCCTTCATTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCAC
+
>F5+96<0<DB-.='FC,)$D=&/+7A*>7/(?8</EC13:7G'+5:0B=#;&--;G);5;
@r8766
GGACTTGTAGAACGTCGGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATA
+
F!>1&6$<4H8,)%+:;,9A%1!79@0/&C1%")'B>.C#>-:'7($+D39222?'(A2,(E"A@(?<*2.>=)G*5!>5*(6':.:E>&+3028'F/2F,.6%B:F8/"40/G"/?*!9=)?$CDA-18%:4H;,C+136DFD"E=9.39%=G>;,>=9(6/2@6F:8*43,2*8*<D!2E#'0;(51"&:A3-/3+3<%C:H/.38CH:'"E(9(.*3%9"G02E2FB<'&.,
@r8767
TTGTTTTTACGTTAAGTTGATGCAGATCAATTAATANGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCC
+
@B.(<4>H*52(5G@B3<2&37+HCF"*(GD*%9H#4*BCA/;23F,2'9B@$A60<29,=</0),+H,,8G".?*-6@"
@r8768
ACCACCGAGTGNGNAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCNTGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAG
+
("%(&&('')%#"!**%'(())&(+"###"#+"+(!&*!'#"*(&$(+'(+(+$&('$+"(''%&$%)#(%"!!)**!$*+*"++&)&+!&&$&#)*(+(+""(#''#&$$(+%'%!%#)#$''"&!#!($%)!$+!"+$&*+!(#)++'(%%#
@r8769
CATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGA
+
83>18$;$#@=&30>617H1?FB2D3<<00<8#8*3=EBA26@)F#??:8'7D$1/F*&?9C)-,HB#=A6??,D11+3G.;?C-F3==5B
@r8770
CCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCC
+
F,3@5:H&.A=HB*?'3@E++@@*#*!:$H&/+*D#"35:8<H"H*D@;G2<"
@r8771
CGCTGGCAGGGCTTTCCACGGCGAAATATAAAGTACCGTATTTTGCGGAANATGATGCCGCCAGCCTGACTGAACTGANTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTC
+
+%($'&$")(("!"'%%&+)''(""(#)!%#)!(++#$+*''!'%$))(%!%$&%*#()!&$"$*)#)(*)&&***+&$)($')+'+'#*$+'*'*"$%*%&*%!$*))*#*%+'"#*%%*%(#(%*&!&(')"%"'&)"!!*#)*%'$#+(%(%'&+)&&%
@r8772
GNANNGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCNGGTGGTCTGCCCTGGNTGAGTGAGGCCGACCGGCGGCTGC
+
%"%"""+("$#")()()"!&$&+*+'"$(''$*'*)*!%+'+!!(#(&))!(+(*''#(+*!)"%(&!+*)(#""$*'%'%"
@r8773
CTCTGAACAAGGTCACCAATGCTGAGATAGCTGANGAGATGGCATATTGCTACGCAA
+
D*??=8!3#<2'!B994.8:8'(6.H>&F*'G+@)(-)"4A<D;4*4".F06B6H6G
@r8774
GTACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCANGTTGTCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTACCTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCANGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTG
+
-.A@-"72C,#@#F4A3H!C.3/&?'59=.C*,96,+%6E?(61D;;/3:>6E!7?!"7<"($=F;D:B8A%7==34@<.27>@>*012#=F/=?#"8#@9!+*C'7GD+;-'>3"'8$9B,-?;HF111G&/C>DE&@A$09G#D(8.)60E%B6G":'+E09=0?+",;!=/03)=,6*%=@#&4++G(H<%1)&&8@+*'6HF#1G9H&C7AF"5=@424&A4E7G"A!E9),&
@r8775
TCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGT
+
1D-632BB!C8/4A,14E":.6!:%(/,!5E0*%!7BGG$99:D,94*8B72>/F1%'?@
@r8776
TTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATCATTTCTA
+
&5)F=62/'9*=?62?H%09DE@A@902$.=<.%HB*GG(C:@;+?33796)/05$0@2
@r8777
CCTTACAGTGCTGGCTGAATACCACANACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAA
+
)&=G(;&19<)2<59B<B4?D-6F*/0D*(75E29.&B$8!"G@)1)4%B0H(>$#!C78=4&D!):@7H!#F14D6#8"E#7B0+7:9+!#@H99-1':*-?25$(7>4*><<0*E<2%3?9(FGF&-"?.=/97@
@r8778
TNTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCA
+
6;.&)>DC1;,1G9,=.1:79C6<=4=(>'BH4A@H0D-;0AB*!)826-G>64C3
@r8779
NTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAAC
+
!%C-$B<72)!GC;"8(&49D?@G>/6;+@C>(-:*8;.E3-<-0:@>D$,'A=.%<AB@&-9C=)3,-14-<F8>'F4#&D4#!/-5<5CHD>?-B,=&C8/"!D;G;GA@?&@2""H
@r8780
ACTTATGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTC
+
B5$6(;.<:H8C/E*:C"!/12C.F(4(/3$1F$644B9/>2<459&)3>46A.7A92??=D'4H$.1--G?<C6-
@r8781
NCGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGT
+
$&%37G?+)A2E,<(4G,15F+3B&61'C)8-+'?1)B@B!>?2;&)30C,
@r8782
TGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTAC
+
9-=6,->'.7+A>(G'*5E4>8)4!8'5A'(.D15=5F%,5.=*#EA%!39="*;-1?@<:30,9#)&2<.20#E1*;FCD+G:F)%::!#;@5#/%$62:>39H>>G:3:-(%?=A5?H5,6D'8D'&+7)A:*@-=755!G$E#+#*-'%*0:=40B07=73C8#8-7FGF-C0AH1A/;6A'D-5:9>A,-$3.%"CE>#H>
@r8783
TTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACCTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGG
+
C6%8$C@!*-$5EG6)-3?C+D>H%&7B68D&B09#>5%92A3B$2HG'"$;-2#A&CC6<!.@0,1:D!0*@-8G2!5$#9!CEF7-()$D>/@7E5;!)FE/%B&F?35./;=,$?:4(EC'E3:"474D
@r8784
GNTNGACATAAAGATATCCATCNACGATATCAGACCACNTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTTAGCCAANATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTC
+
($#*)(*+*!"*'"#!*)!*)&(#*##+"#()%+'+#+%(!$'$%&))(%!$+!%"!&'$'(*"(&%$!$'!('%(+*#%"$('$#+!&'(&($($!$##'+)**$%!$"+*#&*('(+*&%$!("&&(!+#!&"(#('($&*$&%##(&%'!(%&(&&*!%"!(%)&(!
@r8785
CNCGCCTCTTAGTGNACAACCTGACCCAGCAAAAGGTACACAATACTTTTATATTGGACTCAAAAATGCTGCCANCAATAGTTTAAAATCACTAGGCGATCT
+
!")%)($(!*$"""&'+'*#$)#++$'!#%(&+++"*"$(++!*$$+!)##+'"''""#+*%+&+%)!&)#'#!%'$%!&"!$!''$'"*)##'*!+!())(
@r8786
GTAAAACAACAATTTTGAATNGAATGATTGGTGCAATCACCANCCCAGAAAACAATGAATATTTTTTCT
+
)+?;(.:7&E5$*"D("78D;:/C8>)8@"6%D83A8;F)%@AB2-:4D@0C3.<G;8<=?9D1<+5&<
@r8787
CACGGGGNCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGNAGAACACATCCGGTACANGG
+
'<&D.+E=2>0&ED-<;D%%#;)?&@2$)<GE#!C/'B>G&)/.-(?'7D=:6$;8?)3BBA0FG?%2!<(7AD:$!G@#72%:@=+'
@r8788
TCACTAATGCGCGTGGCTTCTGGTGCCTGGGCGGTGAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGNCGGGTTATNATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACANGCGTATTGAAGGCNNGGTCTGGCCAAAGTCCCTCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATNTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCNGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGNGAGCATAGTGCCTGCGTCANCCG
+
+)"*%*!')$%#!++#%!'*$+*%)#+)&')")""!#%'$'**$"%+#("#$$))($"#%)%'#+%'##)*'&(%+$*'&'("'!$!$!(&*)*$"&+%'(!"&&)'(&**&&$)!%'"'''$(#(%')"+*$(()+((%*""$+&()%#**#)#")*"$#%!&*)###*$#%(+&*+&+#&!('!#&&%(+%*"'+'$$)$+"("&!"*)%))*"&%%#(()&#)**$#"+#(&*!''!'(++(#++*"''#"+')!(+!***$&(+#*$*%%!+(#+'#*!**!+)%%+('+$"&%))(!+&&&"!"*(!*+('&("*)+$#)$!+"&$"+(&(+")'&*#("+*(+#+'%'*%"&&+*()%)#$++#$+(!"&)")&%&%)#)#++%'*('!#*
@r8789
TGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTA
+
=H+F26<5%=A4?2;A$C=/(2).1/F*2'>=-,80098<(<'83&30B-5.46:B7:)(>,;8>2C=@EHB5F1$"*F"BB%FG#
@r8790
GCGTTAATGCCTTCGCNCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGTAGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTNCTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTNATA
+
:+"C(&*>8-'>?77B-E4&E?$,,>=:8A7@0@1=C%;E$$H:*G,)5.1BBG$E.,2%=7?#3!4=60(59/F?!:)F80CG;$@",$%'9=H"BE6!#&:4>?6<;"3-1"5;2*AG/$'B=*"&6:>,?E9&'$1D1;0D+/&=B0?%62?50*@%"?8/#0),D+5EFE>:3D0:F
@r8791
CTGCTGAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGT
+
:FH10'GB366'2H'<$4-;$HD"HDGF1<+8G1!E6B25/#$?6/(;,1"/:6
@r8792
GGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGA
+
3:=%-G,</E-,6E'0D!0A<!=A#@GF0/";;!@*G/2#
@r8793
CCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACC
+
=(7*;A0'E=A6=D-92+36G'3??"=2BG0&8?7F@.13G+7%4$$E!8;B+@H/1FA&3G#/.!>1?.A!#3$!)")&C"10+<6$B4$>9<3AHA,6?+B24:H0%+54(4"-*+A!;!9/F,?41>+!?"DB>&78!A/!@:@,!G0-(9?*GDCE2?#&.'0">(;/5/":E"6A4C;!)!
@r8794
TGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATATTAANCTATTGCTGGCAGCATTCTTGAGTCCAATATAA
+
=814A,C+=7''?:)1##*;>AG,-9+)53=C%B2+89$*D6H3C,:?GH-22#3#B'$<9@A/3!AFA:DH"?,77-9("81#0)</CG/B&:#G5?**G&/?8+A9+0#
@r8795
GCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATNTCTGCGAAAAGACCGGGATCTGGA
+
'3+=:+:+00B!;>=:4>"!&%BH#G.3?269A8%+%7B$)/,<-$CE.-4@$H?3&3A"/@D3E22'F
@r8796
NCCGNATGGGAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACT
+
'#''&$#%%+$%+'$"(*&#%'!!!)%*")!#++%"!(%#"&+"#!)(&+"(!"%*$+()#%'*(!$+'$%!)$"')$!'($(&$&)!*&&'!#$++!#%$+(*+!%(%)+)+#)*!'%#)%$"'*)*&($+&"(!%$&!+)"&(
@r8797
NTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCNGGTGATGA
+
!$E)>=ED(-:0:H/"5B4F6:/G0HE&1%5-*/22@#D,19H="?7,,--8$(3
@r8798
TCTTCTNACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAANCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGA
+
=8.@#=+@+&C?8CF8"28*G?D%1"7)46!+B;%HF&&/*!//*!>6B82*ED0##E5*A8#9D'D720!4$01>0!0;"3*34/6(=%$GC4G
@r8799
GTGTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCNGAATACGCCCGC
+
'#!('%%++*)"$#&&!'#+#!))!$%!"'%('$!%&#!&!#"(+!)("!&!!*&+%'%**'&'+&*%+!'#*)(*+''##'%&*%'&++'*"%##&"'"$&'+"*#)+%(%()*""'+!+*++&%'%$$&&)!("%)*#%$+&&!")+)*&!
@r8800
CCTCCGACCACGCCANCATATTGAGGANCGCCTTACGTTGATTATTGATTTCTNCCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTCGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATA
+
AH/<F3;!>*EA;0<H>4;>D2C%,:,D.=0H8*$B+(#$:,.&?<G:@H6&0G?9D3.&5-B$B;F1"+A=*@<0':E0;>7.'5)$D('B6;;D';*,?C=5CA*B>.>:2B)D9)/)A!A!.B&,+G!C4E@AG67.-E.;(39?$#,A981?HB'6(+<4D*@"E:BD-6=A548&2?,6"F.7<E(F008'(8/3:CD6*H*
@r8801
CTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAA
+
<-E*&>"$2=)-/)E9=<+FD8(B,/?1AH4=>"47"?"+20<>-$$CC;4$5%&'/);5%/>;!!'$$.+0-9"!('#BH%@>+*@)?F/22'
@r8802
TGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTC
+
2F(C6:=-6F#!E*0/>5!;.1;%C".::4'AF).7<51!H.-A?'931$;%5>.%-+D(9;GH<9AG<)+/*?1)78!6;1G5@"7
@r8803
TGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAA
+
6."?(E1&:*=.6/92=4&C$$'F7!6/*1"A=6?-62=/,(7?>H#B41=(2)$%%<(".A>EC35198%H*2
@r8804
ACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCT
+
@0;>EF;$6;3B1HE3:';'?D/0.FB,D9><C2.>/?<D98/,E2C("<>7'1F.-3
@r8805
TCTTCTTGCGCTAANTTTTTGTCATCAAACCTGACGCANTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGAT
+
9&CB00$1@3F*-;>0,77%?98$F'FA'-;!()C,C,8A?G076B<=36G8CA+#())666&)F:@9!H,/:D"25%#E)%9,!@/:#$;8H.6FD!9+E&!(*0H&F$5??E,12752
@r8806
TCGNTTNNCNGTTNTNNNTNGTGNCGNNNGNACTCNGNNCACNGNANCANNNNNNNNNNCNTNNNTNTNTNTTG
+
$"$"##!"$$$##!""$!!"#!#"""!#$!##!#!!$""!$"!!#!$#$!$!$!!!"!#$!$#$!$$$$#""#$
@r8807
ANATATNACTTCAAATNNNTNTCANTNAANAGTNAAGCAC
+
$%(###"$'%"()'*)"'"'""#$%%!*&!($*"+(!'+#
@r8808
GTTTCAGCAGCTACATTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTC
+
9>AH,47*=1=&0;"78%3@?)&$@$:'5"$&$&?->D2',.-C7H-,!87F,8F#00166/$DBAHE:'$:5GDD<.%<F6;F1!A);2D)($2#*DBA:!%0".8'A;-1%DA,==?$=CF0
@r8809
NANNNNNNNGTNTNAAAATTCTTTGGCNNNAGAGCNACTGNNANGGNTANGGATAAGNNGCCNCTNTANCTNGGNNNTCTNCNGACAGCCNANGNNNACGTNNGCCGNCNNNCANCTATTANNTAANANCNCTNTTNTCTNANTCATNNNCNNANNTNNGNACAGN
+
#"!!""!$#$#!!##!$"$""$##"!$!$###!$"!##$##"$#$#"!$"!""!!#$##$$!$"$!"#"$$#!"#!#$##!$!"$!#$$$##"$#$#"$"!!""$$#!$#"$!#!!#"$"!!#"$"!$##!$$##"!!##!!!$#"$!!"#!"$!#$$"$"#"$"!
@r8810
AAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGNACCAATCATT
+
H;<>C&!B&))@%9.C%>B1>,##4DH'"H<(@:)>'),C%,8%(!=&6:<::*7#-GB!5D3A=>D65*DE6H8!,C"!$8%8;7B6)25/GD?DCC(.DG9'+D;,A:.%8!=6$E
@r8811
NGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTC
+
(:D0)D%D#F,453*'44$<(4/!--+49.',#@)*1A1E+)+9B0GF&&-)'
@r8812
CGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGNTGAGTATTGGTTTATTTGGCGA
+
0!?0@(!2/;-FB9=01B9/+BAFC-#?%?+?.G$*C0E9=$0@,?'557(+3-B5-,(;%3F?3(7-'!@#/F&BA6A=>($269B,%90
@r8813
TAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGNTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAA
+
7,9A#AE&E(B=>B*25E949"$F5(D2$="?-$8C;30G?C;21<C&E;=-&<8(=$2?!:"("&<6;:.C782'7<C"5<"08,'7?>>G#@"#=:)>E/>="6(=:$F2G8C8:9'';-.!61.#:<@0!
@r8814
TTAACTGGCGGTGACGGTNATTTCTGCAACCGCAGCAAACTCACCATTACCGGATA
+
78B-&:8&<C-.4=(*C;)0!(G"3=)?3+(,+<%8?.7!BC7&9-+G1"7-=!"1
@r8815
GTCTCGCTTCGTCTGACCACTTAACCCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATNGCTCCGCAAATTC
+
B"175#=*@;>GF8@75#00/A$#"1$0G9.+"EF6%H*2A=,-@?;D=+&>/";*&#?7C8E"0/<F%BD7--==
@r8816
CTTGTCACGCTAAACCCAAAACTCAAATCNACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATNAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGNCCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCTGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATC
+
)G<'+&2'G/=;:24+32$7D<6)8="G1C=1:-+/&4%E#D&1=&'%"?A=%?-!AH"722=B+$*@);66)($>%$&.%7=,G/*H$9F!)&!,:9>9E-FDB,'=%(=;*><@2HD>6339$*$@$?C?=F<4F5$3&C2%..C39<D@.3?>%*D+:-@-A(8*=*+B"C"D-!5)D.%GC267&9;/>-E!5(=#$<F/D!<,1>&8"B;9<,G%:9#7%4<";E%,7;;9(5;(2>6;;(FF86-(,#G+<@.C<BB<,!3>5GDA>C%E61))2/)7(%<,7=31@1B.'6&2F)/#"%HB)%;(#H9HED>$G#1.?D21*;+'5B%@G57F9/<0G797-*%54,19A'4*&D6
@r8817
AACAACAAAGCTGCCTGATANTGGCCTTTATTTTTGGCATAAATAACA
+
F$:9%6=-<(<>5H;D7$3-*="@3B!,<33;*417!@$*0"A3)?*#
@r8818
GACGGACGCTGCCGGATTAATCTGTATACCTGAACTCCACGCCANTGAGGTATGCCGCATGGCACTTTNGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGG
+
;0G?6,$2="=7&A;(.=)!2C1G!9#@+(#B/>(F5');:2E6A('#=B*>.F<D@B!:'?(!%1>6?#D+=C%/2G6!5<=$&%2:83"0C>!*/6+E!G2A$40)A.3#A(!89&-94&5A*!GF=?>0C>!-=DG/,>1<G)<F6#(A.19=HG6$;0('/C"BG)#31
@r8819
GCTTCCGCTGTCTTNTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAACAGCGGGGTTGCATGATTTATGCTGATGTTTNTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATC
+
03=G#61D%7"2-=1DE#E!D<8*H+D>EA<F6&42-/8(@8)<B$*9"%F2<F<F*/2+0#/'%%.(364/!&*<C%!C)-6;F!:,-3)C"+;.>?E".!/'+5(,$3D=#/>@7.0'>>#/17"<,8+*C2!4H7"5+"1'"-0*">:<>-+$#G22/C1&1#@"F=130$33<:G62-9G.9H3@F4E1;<F@,,?+#G%1((.979?"'AF89&7<;(-C37'2%/B>84+;"-,#75;<&6("=2(#B'!H@B/+F$8B*605)2-G!43=4+</
@r8820
TGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGAATTCTGGCCGCAGNACCACAGAGTGCACAGGCGCGCAGT
+
?A&?*#&595<.9>>2/F<C;4-*<B?;'920C9,>H2+0@3/,$=-B*:*D@C@=+>2>A)-<+G%/@*F7,"5"80090&3
@r8821
TGANCTNGCGATAAATGTTANGNATNATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCC
+
!("!$$"*)!&("$%!(&''#!"%(+!+*")""('#()+"'%!$*')+($&#'!$+*&&$)%&*$$+*$+)+)$&$"(+$&&'*(#(*('(%++!+#+(%*+('#%')*!"$$+%"%))''#"%#$&))('(
@r8822
AAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTA
+
=D,/+G#1B+%-7'#F29/E82)9$D4*(%39)>(1)9821?+9G):
@r8823
NCAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCNCTCTT
+
&8#F%3+E<&"'"(@3@05%>G8+$A2!#$'-1*F+2.FG+FF%GH525-H>=AF8!.-$)';(%*C&986;;6:(1?3==3!.692D4D+,&(B;/3G.B?#FB%0?&9;&:.2='@/"
@r8824
CCATCGGGGTAAAACCGTCTATGACGTGGCTTNCGGCGACGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGNGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGA
+
-DE!GB<3<%(!:<D.$>""(@)!8E"FG9:';0.C=;23-.?AGHCHF9&+?+0H'"-H;;*.$:<1C@:86)F-;!B4<6-.@E+,<(<$/"=-<1*'@8=&&;>9D,',+!8,B!"B@&4D,,H0'+H4.9B766-.&H%4"265?1F%<'>6/89!H1&GH?01,2)0F&*7+1..'9%
@r8825
GGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATCT
+
?:0&3*H3+?:D)=AB+1&1G;<!;CE!HGEH9H=18,-;<+,F/G+H(0=4<G2=":*<B0=H'1'
@r8826
CATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTG
+
2=C?*G?6<25CD*+D6%HD&'3<C475/34#*D"2@2:/"4F685#A,BA1>:9<*;%G:"+*B7$F@D*C?845FD-82,4C<%%7F-4<A@B-!A9'ADA
@r8827
TCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGTCGCCGGACTGCGTTATGTTATTCACCTCACTGCGGCCCA
+
5'3=,%E'6@$:56$@6.=FF?<!+2@:*.=<6*FE5!;6);=780"186-)%$=,?"?F"2/#5A6?8G?8&-.%C4HG?
@r8828
AAAACGCCCGTTCCCGGACGAACCTCNGTAACACACTCAGACCACGNTGATGCCNAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATNCGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGA
+
:BB@:88/H=>!,F?>!&.)??)>D%D)?28A;&'5@9<E"&++H4)GC/2.(;:.$(9>/'AA<<+"?FH78.&2)>698:!/E#,?')8B78$;)+&0;*2";E1&'5&DB+4!@C3":)",A?6<*++?2;;2683!>%,F$9(%9'@!,,C%52'E*$937EF5(
@r8829
TATANNNGNAANTNCAACATAGGNCTAACTCATAGAAATGCTGCAATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGC
+
$&&)(&#'#)'#&#()**%#!#)&''+$+$!(')*)!!$**)*+'%%('$$("!"&&!)$#+%%&'$%)++$+!&!$(#+!&(%)'+#$!!%"$*+#'$*$"$(%'*($&&'&)&+$&'%*"'#""'"
@r8830
AATCGACCAGTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAAAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGGCCGCAGATNAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAA
+
70*@1F>7-A)C7*"G0/-"E/@03.A8)H'>%A$3:-5:-(&4F5?2C@,B2;5>&"E)DC;8D>CA*%'G*3;+B:D@7<@A:$(+GB7$4F'C:?2@70G"B(27"B5$'FA48.-)&F+:>D5%25?>0A3)(40<?):&(H,A!*9,A)$-;"<*(-4"-H7<=E*D.%,!466-<3%-H'@:+1DEG6B:36&'%B*G+4AG7(-54A<6.&$F'A&;=)8;D!1943*?)/=)7:%?3+,.E#='!+3=22"(-;)359F#.G69"DB%-,*D?=B2H565@E1F=F2*<(.2>"
@r8831
GNCGTNNNNTNAANGTTANNCNTNTCACNACNTNANAGAGNNTNNNNNTCANTCNGNANTTGGTNCACNTNNCGTTCG
+
"!##!!"#"""!!!#$##"#$"#!$$$!$$"$#"!!#!$#""!#"$#""##!##!"##$"$""#$!"!#"""$!###!
@r8832
CTGCGGNCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTT
+
"+)%#)')!"&&*$&$!%'#+&$&%"%'!++#$$'"'!$()##*$+(')"$&#"*$'#'$%&*&&%+($"$
@r8833
CTGGCCTGCGNATTTTTGACCGTGGCCCTTTTCAGCCTGG
+
0FE#<-<C#GEG7#./++%=(>+;!5#@B?#2:8*".&";
@r8834
TAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAA
+
#1A23AFG8<F>F"C&,=D+'3"'1>=-B/??.7;@3-<@$6D78&!
@r8835
GGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAGATAACATCGCAT
+
B!H2#=#D@9&5"+GE=(8&&;-3.C&!.?-6BF92CD,2H6%25!AA,5
@r8836
GAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTGAGCCGTGTT
+
G4)>A+&>2F42-295A28B$;=3"&!*@6;7@47$=$)#78.44$<%
@r8837
CTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGNCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGT
+
-13B,1,670(8(;FG614H?%)!#%C9/9419A#8">#70E"7-3,7ACE809=3+G41)!85-#<'?F'#A9>)=E&+E6)")C,)@A;(G+93;$GD$@F&7:<6$&.1+5%3?CF/B>:3'B,2(?HB>D+-GA?#=/0-3-F?15AG!!4-H(A30ADFC(D=9A!E744E2;'A3>):4'7G(
@r8838
CTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCG
+
G8;!G'+3;(,(7#(:7$<FG;8BF:G;101>HAA+'F*B*H+D&&9C%0#6.-A4<</:<H=FB9%#BB(B31'*?8.29+C,"5!*32@0'
@r8839
AAAGTGCTCCCGGATTCAGTGATTTAACTATNCCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGG
+
-8501,@85;CG"?:;13;*:;'7+@$$+6.>'3'>.+-A.$>$HD99*H7-#".%9*$D:18"C","?7558#$7:-G#@=;=88;9H6.B%%<G!H-<D;-
@r8840
GTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAG
+
:(&%0EBE;%!$E'1H,H(8B%-$@8"$.AC(9<978,A1:H%*,
@r8841
TGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCC
+
G$C5;27)/H*$9/"/E9B$*C'*5H>C.:0&E)5(11""30-3
@r8842
ATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTATATATCTGCACAACAGGTAAAAGCATTGAGT
+
.%%/*7>+-,A6:()15B#9F4H547-A#;+:9@.*,*+*>GD&97&1,!52G=%-5=(=?0?C2*
@r8843
GACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCCATATCTAAGTAACTAGAGAAAGGAATCGATTTTCCCTTAATT
+
12'=)2$A/9!=',<>,"<H$2(-(9D3F5$53G9B;.H34AH$D=#*&H?&!:8G)4.'HCF4;G2.+79'.D'#B=<G/'==:43:<)!7?-?GB
@r8844
CTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCT
+
H$=C$+E;1/!C1%C!=*1%B;D>@0&)+.?-(?1@GD80/-DF$./F$3"6%3"9!2*4B";+C"@>@D(
@r8845
GGNCNCNAANCNNNGNNNTNTTANCNCANNNCCCGCNCGNNNCGANANC
+
#!$#"#"""!$#!!"#"##!#$##"""""!#""#!$#!""!!""$!!!#
@r8846
CTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAANATAATAATCGCCAAATAAACCAATACTCAGGTTTANAATATACTAACTAACCGCAGAACGTTATTTCNTACAACN
+
&+"!(*&(#$$)%"#)(""($"#!%*+%!#+$$**%)((+++&$+#'**("%%+)#*)()%"#"&&*'%#+''#%&+'$(*&)'*'%#)))$$'(!$"$&(++&$+$($'+$(#&!'##%!#&!)($+'(
@r8847
TTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACT
+
4H:#6*E?)CBC*<7,;"4G.?"G-"E*9B.;"9&="H?@'@A%,@,,/E90049G9?4H<@@-6=8;H.<F41>$&'G@02-2+
@r8848
NGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATAT
+
(<407&)>8?ECA*(G%&&9+@)F17#2:(<G8&6;!24-&389*A2)9'A'H>FG*3%EA4';/("#*B$!:@(&*H7+D"4?%7DAF/17:*/.HA0$'56:D#924,
@r8849
CTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGTACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCC
+
.?!!&D52!8#494<#7&9)/,0!-'--+=>7085:8+#D$*$5G4B(&C-8G,$*1/)56?%?&'F;6F'.,<-$H&ED3EA@D)A&C%&B+F8@-%&!4-*,/#:(/,B'H97*5F'2"&A$/#5E;
@r8850
NCGTAATCATGGCCCTNCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGA
+
!);>>+&?15#<EF/#3*)1."8-%'..'&/G*$)7!)6=638%/@F5.3)
@r8851
NTNTTTTTGGCATAAATAACAGAATACACACTGCACTGTGTATTCATTCCAACGAGTGAATA
+
"""3@G?/9$C:==;)H-,,@CFE:35!"2'EBEA?01//%C2;>,6,ED9D*#@H@50?96
@r8852
TTACCCGTCCTTGNGTCACTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTC
+
5<<G6CE(=#0#6G,&,6;38!"E0=A*!+AG5!-4<7*B#H30=./;,9@&%093D>@:0F&5.E/A9FD/-)-,'
@r8853
CCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCNCNGTTACGGTCAGACGGNGCAGGAAACTCACGCCCTTCACCACCTTCGGTGT
+
?=(F&@4F/C>G=D%7<>&!<-@!3)45+!EB9>C$5>4"A"D5.="/=+8177C!'.@4-)7:"!%&*'876.(32)!0:+)%.H";HH
@r8854
CGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGG
+
;3%7)A>A<075*<F&?.$-92H831@,A%0;17";*C6G#01*D1
@r8855
ACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTNATTTGATGCCCTTTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGG
+
(8A:0;AF#!ED)*@+!648#0F:(!),"<(@+)<C<',$<$D$?4.-16*(7/(<$+19$,7;G"&A7;9C7*33:,E)B)'0"GB>4.&':%;HAE6#51@,$5*B>*G/<-E$C:3*"D?63#83>39)C!0
@r8856
NTGCAAATNTNGTNAGCAATACACACGCGCTTCCAGCGGAGTATANATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGNCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGGGTGATGGTTTCCTTTNGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACG
+
"))&%&#"!&!*(#*&+$%%!($''%+*%#!%*#)"$&#('#)$%&*)#"($)"*)'"'!+")*+&+#+%)(!!++)+')*#!()'*%!*%%+!%%##))"+'('('%*'#(#"&%%#&!)!!"(#%(!#*'#&&"$")((*#%*"+"'''*#"(!%!)%"+''#%"')"#*&&#)+$$+)(%!$$'%"(%+'!&'%!+!+&#((')(!#$"$)&$'+*+#'&"'"+$+#+#''&)*&"
@r8857
GCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGTCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGC
+
C*&#5:3C".(/<0=,D$#@*14&778D/3$+@HH**.)&>B&*-:=@$"#><"=*,FA"C8H"4>4#)E@268+&'1*0AC3AH"HG86+,B3$@$1'77=1+(1'%4)0HG1:D-!$.58##C(<G0>=;0F8:.@#$6C-C/C#03>)FD-4F,0FH*,#F%<?A>=35!&35?(&E&5=@'=%2:A71F27(-E6-*6@%F1#+,C"E@",C'>
@r8858
GAATGCTCTCAGTAAATAGTAATGAATTATCAAAGGTATAGTA
+
AE?/;/+&75H!HA?(F/G(F9"@.26D:6G"8'32;$BG,"F
@r8859
CGCGAGTGCNAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTANAGAGAGGGCAAGT
+
A@A:#B55:%1<4E%;5*/,)7*5659>#DF46.-E</G+..%;,G0'5/A#%2:/C"=#$>)$;6A1-
@r8860
TNCAGTCAACCACCAGGGAATAATCCTTNATATTATTATCGTGCTTCACCAATGCTGCCT
+
%&$<A)&)-GA?F(?-!@<(H:2?@D<7=F+&@9?(B+?B':4B?0.+2>-..%7C<A)A
@r8861
CTGAATTGTCAGACTTTGAGAGGGAAGATATCCTCNCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCNCGGTAACTGCATATTCTGC
+
+3H/"C!7+<!BAG@2@@12."=$G;"=-!80=G-(=:?:8!G7.C>0,'(/;B:=0=3;5!A$>.(=:B1+6(@"5AC?4,4F,.B6GHC-&AG$FH.F-
@r8862
AAGGTAATTCCATGACCCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAA
+
4690-(?(C7**+$550H5'-;86#)')>'*D5>4*$-#=555"%B/F05A/4:'0!:-
@r8863
ATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAG
+
C&9,57A$(<>**"A84C55E@E''B(G<4?<6)51)B7D(DC'-"@-B18)F2.63&0%B.8G1"&E1GF-5(9%A(0
@r8864
GGCCGTGGCAGTCGCATCCNAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTNGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATC
+
@FFF2*!;2&7C((C):>&D2(-HF,&634G,&9E?=>-&B*G8+7EB199%A%H>A1E578@.-GBGC9>:61;G&?E4D:D@228$26A1F6'#(F%>:&'(&/%2?7))A;AFD!G5EE?-212!'%;&;/'<C>8<)/5)A=2F15&64!178E*>9
@r8865
AAGATTCANAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGACTGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGATGCAACTGATTCA
+
)C,.@=&:-36+0$"D',F>?944)5G;!>3H5=(F>%D7B3A$1>F1A!$+797@04$'(#D9%(:C3,2EB.=H@(-%'/-7@12F#/<49,$1D3&:749G9%?<G5H3"/D#>#*B5<($$=9D?7?7%D>B"+@"+$3!C0,,6)BBC#<92$D,EE((<31E4%07:1(E0E$,;)?494A4/9GG0"71)24,D<;E'&F9H6)$)-*>37
@r8866
GGCCGATGCATCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCA
+
+-<:A-1:3<'=)7116696*'(;F+B-4%%39-(@D7A/%7(5;BB7H/1?-E#>:/'4C*)!?-2>?#$.6=2(/&)</G>C"".A&B)00?2+3>6..%F6/906@G%+%3D28CH/6%BH
@r8867
GTGTGACGGACNGTTACACACTGTTCCGNGATGCTTATCATCTCGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGA
+
<&+3)!>+3?B;8F+*F1EH>;7&FG??;H".@0EH:2&3,G>2116($.'1D#DG'+!"<C7/1>DC7<G'690)93!C./
@r8868
CCGCGATAGGTCCAGGTACAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCG
+
F;-'<A):%'$#8035B!A!7E=),.5)H.,G.FA=,6G&B0#A30%*1E@7.BGB3&)="8B,A@=009,82)2<
@r8869
NAAGTGGCGGCCTCTGACGNTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGC
+
!D&'=GA=G&3*#.+!"F$"#!<A==<>3C=9?F/574+E?-4@GB2$3?/?G0</1D;,)2=F!D$4
@r8870
CTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTG
+
D9B"&("+HC!<D3H0G(-5%?(2?A186/H49D-3:<!:0/C5
@r8871
AATAGTCATTCCANCCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGC
+
'+)++'**#*&%!!&)*&%)&+!&)*$'##"#++')""(%))&"#)%(&%+!
@r8872
NTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTATC
+
"/57"'5/*(E<$.?H<"G":?E&&1743E$((*?5925,2:7H<2
@r8873
CCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAA
+
86$/8$E!.F'>%F2D:96*1:8&+-5)&*FC,<B6+B"A9A5(?)6)
@r8874
GGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCANAAAGATGAGACGCTGGAGTAC
+
DG:H26<)F&!-.9@('<97;7(-,<901,1-(+$)>>F+7?7!&A.&HCF,)</142+4GC41-12=#8(93E&"
@r8875
GAAAGGTCAAGTTTTCGCAGTAGATGAGGTATACCAAGCGATTC
+
+@4&G'?#A:G(@@H!&$#*D&9B445!C:C+%D1&%=&BG7'8
@r8876
TGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTG
+
45$2<AH(!93%:&!58C1!(5B8AF-3@!/F$'$'B;A+"DB1
@r8877
CAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTT
+
C>,+26-%28=;''F4<?$)1G.6@!B>B<<(@%;2-:>5(G)(&;;?2*>GG$(9=E&DG!<!+EG<6G,'1&+!;H.*6,.B4&5)=='D8:+?A)1A"78
@r8878
GAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACT
+
6&A&/C+<)41/?=;*'-!C2A/&>6'6H@=4=E""4&(+4(E,C/";'8H'@G#?@@+
@r8879
TGGCTTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCAT
+
>1:8?5".)#73#G%33*0/-C!H,@=FC&A;C4.#354)/:8"%<+32!8F9CAB1=@-4=:4=G83*E,3$$E=-'9'3<,2#<;26-8EF";<
@r8880
TTCAGACATTAGCATGCGGGCAAAAGAAGAGGCCNGAGATATTTTAACAGAACATAATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAG
+
DF<3H,,11DB@C6+797#8=:9.H6?:#=$>)C<+?;6/=7=/>35&-6G7=:=0<'13+$C>%C3:.#%4.>!A("!0=5(03)>E/005.C%)"9%"H;;D/49G&*GF@:&E
@r8881
GCCCTTGTTCNNTNTCANNCNNCNGGTCTGGTCATCAANCCCTTTCGTTGCGGCCTCGTTCGCCGCCT
+
")*&!((%#&#"'"'$'!#*)(*+%!(!##(!*"")"$&)*!(*+(""*!%+'(%'#%%)+%%+!&(%
@r8882
TGATGGCAGNAATGGTCGATTCTGCCGACGGGCTACGCGNATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTT
+
*&?#.5-:=H,+54A?H?8A3"65=?1?1'2&:0&AF6#13;9;=:':%H)1#+H;C6#D1%-,-&20$*7**.#*BCH($#28*<<C<?347+.&<!2$(A9EC=@%&@*4#"7G-
@r8883
CCANCNCGNGGCACTGCTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCCTGTTGTAATC
+
**%#)#%''#'!&'()#)&+&$"+#!()#"%&+&$$$""&'!&(!$%+*$%"!##&$$$!(("&''")!)&%)+"+%+(
@r8884
TGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCACCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCG
+
HF)"74H4-C?G,,0/(D&943B/77)967/54%/!F=F?FB3<%'#69.1.$.D!*9GB.=?->+2**..!D&3%GGHB*;!76<987G-;<:
@r8885
ACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGAAAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACNCCCGCACTATC
+
AE0,((5CC5"HE'@0$.G.98D4?,E-&>=914+%>#/0*A:@@8>671B9G#0$:83%3HB"@-!,6.)29F33G4/2->F%;@,E1"B137$(3/78(5)E'?>>49#:F*C?49D$9$5*-44C7(3*AH+?/(8<7&)?0#F=E"2&659<:8
@r8886
TAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACA
+
2CE>.F=?(!67/'>>6'&7?-8%52/#B$.26%A%-A3/H8$/>.9;8)=A1544D'?%HH4@F#@DH.E?)BB></=#.&(E
@r8887
NGCATTAAATGCTTATAACGCCGCANTGCTTGCAAAAATTCTCAAAGTTA
+
+$#*!'+'$"()(%(+$+*(')%&&#((*")$#(*#"*&"$"&)+((#&#
@r8888
NGGGTCCCTGTAGCAGTAATATCCATTGTNTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCNCATGACTTCGCCTTTTTCCCATTTCTGATCCNCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAG
+
!&*)+)*)++"+('(%%%%'&&&!&")!+$)*%+$*"%&$%"'(!(#''""$('#'"("+!""#(!!)('(*+)!%"$+(+(&++%!"$)'*%#'%$+)%"('#'&"++*#+"($('%+)##%#*#''+(#
@r8889
CGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGG
+
4>G*,1-/!0)=>&&?!B!61:G:74D8?;!"D6B&&C,82000E/1D)$..)/%G38:-$E8;:2/3181&5#3.&4/59<=H9AFBC.)#72/&&$;<%7<44;(F;":=,&,#2.,2@=E29:G!0!C8B(D/
@r8890
TTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATANATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCT
+
7(DEF(/:45H+=7*D.FG#;%$CC*,=E3$D*5*;6HC$39',20=/(%-H*7":$#;)**6C(@"A'36++)**3AC;A0#G#A@";6C/'/@&/29.*!)"-==;@?)-/?5)8&*,(##CC&='@3BB:!.D3.2D%E>:*%#3G:5E2#CF41>3
@r8891
GGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCNATCCAATTGATTTAATCAATACAACATTTGAAGATCA
+
=E<F/.=.39.-.$.+05A)!E:3%D'&"+9"F&<6";#(,'GA/D;7>EBH646,=5DD(2&?9;?>;?@8;D=A9(A%$G1B
@r8892
CNTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCC
+
+)&)'(+'"'()&*!+'%!)"#"*)&*('!+%)%''"*)%%!(+&"!*"&"*+%$"""&(%*'#!'
@r8893
CGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACATGCAATCGTAGTAACCATTNAGGAACGCAACCGCANCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGA
+
+H#;)GB.*"F>64;!HB!0H&+?1(6*=;*B$3F(*)3.)//507!%?0C5(37$D<*75H.E5<%,0H')H-?#0G7#8*$E3A;6:#13$7=#>$+:(4H$)A%@,230A/E(%+#64A:2$5>6ADH1@#2AH89#G%G>"AA9*#/D@<@?&8:(A;D>E7G!CE#%@@8+HFA%B2G9
@r8894
AACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTNTCTTAT
+
F;?1CGF@E,50?05E#4F/50;A$G1')>%$$5&0C(2)4A(8H866!49%)
@r8895
CACAGTAATTACGGTGCTGCGCTGGAGNAACAGGGTGTGGAAANCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGAT
+
A,3FEBC>3E./@6?5%HC29<)E.2;2G!!#"/D2@!G&('FA6-9*;9*>5(?+44,#0>##/14B<A4'+CB(?H?3F>D*+12>0>;4A=9*E(G+2#461
@r8896
CCGCCTGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAAT
+
BA6*G980//,.&9C.@G&H-:.5>(=1+=;A>7&'05/5,3H&C>
@r8897
TGCTTNCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAA
+
AGG:/+(/?&.9B!@3"F798#01)1A$->H=>>B!$=-!*5>8)4%G<FG(<HAA=.#GFB04?$=FF(BHG-F/-$)!F%30F=(4<F%@
@r8898
CAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAAAAGG
+
(+=DF'(9C-@$0=*6)A,<)>@D9;/#:*&:.C+=,:?3:??G=81F1(;%;G;/32%=:6
@r8899
AAATTTCCTGTGTAACTAATTTANTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAANTTGTATTACATTGACAGTTAAGNAGTTAATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAA
+
++)(&&+#+()"*)"$$&&!#&$)"##%*#+(!&&**$)#'+#('(!)')*"%$*'$+"++*&)*''(""#(%)%$!"+"'+')&**$(*"%')!+"(&$)++""''('#('!#+++('%)'%*'*+$#'%#+"+!&"*+)'$
@r8900
ACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCT
+
B)'1%4$EF4%=E,7B%;54A3F+%%5BC./,D545%3,@8?$(
@r8901
TTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAANCATACTNAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCNTGACACCGGCGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCNGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCNGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTT
+
3!2F7#$D:!%@")G&@7!2*>-6"C??1=0;@,H52'3!<B4:)-+63+@H-!AA'!/50A$::'=7(B9':6"*?F@->F4#8D=0<1>%+*E(93A&6?C.G>.4@4:B9"C#/AE5<4!55,B'4"/9F'7=$/(@2+"/G$H4:H.,)%(<A%'H!=H1G)9*G0)@(*#!-*+(-><$"";+&H1(#.6)/G3:)429B69'53D+.0/>*.'=$H3G<0+17!!*$>24,!H$('=894%@;H,-E69A(7C%C=)/@%;GG'8F=3:"A9E3-C8H?G'%(&E,&(56?%*:H'+G2&1!C&@D;=+?=#6HG*21.<D+2'A(&8=#'EB#<!;CA6-CEB(D3A<5,$B3@'!(18<:G=1;)-%B>$3C4H#8>9"023E<.CH"14#@)"2FB;*>%20)B
@r8902
CCAAAGGAGATTATGTACCGAGGAAGAATGTCGNTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTAT
+
%)5/4+H:<=5!,=6%!BC5;1H0385.>/3A1>$*-;?)!1E7992?+>F)D226#;G?*(%';%/)@F'"
@r8903
CCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGANAGCAGGCGGTACGCATACTTTC
+
A'*<3)!F.-H.6!749B;2H>(7HF1'940.5+=+%D86#*#=F<!D"B.;D:;'E7":'D?36<C>A&36A+H@<1-3D)2?&9)==D@D$"0E;!GF@!
@r8904
AGTTTAANGGNAGNCGGCAGTGCCTGGGGGAACTGCGACTNGATAGNCTCCGGTCGTATNNCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCCGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGG
+
)$''&%"!*(!*)**%+*$#"()*'%+&(*$(*#)*+'#*+"!)*+$%'*'&+$+!(*'("%++&)%$$""+($#)"$"%$!&)"')("*#$)'%"(+*($%**&+%)!#++'#')($%*"##&*(!+**"!!$&''(!)$+"%"$%&+
@r8905
ACTCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCNTTTGAACATATCGGTGTGACCGTCACGCTTTCTGAACTGTCAG
+
@//&.?-/%$84:!$?0>)95/1(2;.!<BC1,$=,4A@>.$2&/>@!F4%;9(E;@=!363!#,C67'0=0"?:H*5DF+
@r8906
GGTGGGATCAGCGCAGCCGGATACCGTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGTAGCTGCATACTGATGCACTTCACGCCACGCGGGAT
+
2#%.C8DE$:G7C='A,!4G>;0/#4.#6,@*A*G:%,-81C$85/7;&9-&8CA<346$%CC3*#)$20.&(-@6D&3#7@>HB?D<E-;9$02->)E;E#308'
@r8907
CTCTTTCACTCCATCCGCGACGAACCATGANAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTNCAACGAGCATGTCTGGAANGGTTTTTACTGAGAACGT
+
D:.90>>80890=)*$G/#3-,D5)5,-$;,B4*,<(*.%2%DCC!?7B:2.E#67064%3%>F&B(=?*?>,)-!E0=1:E0>EB1?./.)GB%2+(;&G')8+C@%+?E/.DAC'2F0GD:GH$,?1((C!G;:4*1&$B%2*3>+(H$(8<)6',0HB%/-,4.9;*6F0H=%@*7=F
@r8908
AGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCC
+
4=G2G.!C;&.C/?:/&?E!A-41:6;'(@H7$)&EB;2>4#0!
@r8909
NCCTGATGAAANGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGANGACGCCATCAGAANCGGCGCGTTTCTGGTGGCGCTGTCCCTGTGGCATAACCANCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAAGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTNTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTNAACAGACAGAGGACG
+
"'?5+;02-E)2F7:'=8+F6H30!9>68G3"+&6*?-9=A9>,0-%47H5569=D1?8'9'$$4+$247#020.F-@C-HG!$G?<7H,-?A8<>D/B"*$<6&''!'F;82C@#=88,F%2-7,6>3+/?@-2/HF@-(44,>'62$!AC85495G44@>81A4/7!!C'G("+1:FC+G/4H:;&E,D43DC&/$)%(E:E)*-4B,,8*H%GG$;<*:0>=F=<-D6A$>2@$@<4"D<%2F;D-#2%C)8#<1+G*.-2)):>939F",9:7$$636&BE
@r8910
GACGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTC
+
!##5@<<;=;$""@8"#*$A942;=1,:<CG!&!-B$:5#97FA%$!G:,.%6B81>$
@r8911
CTCANCACCCGCACGNTGAAAGTCAGTGGCACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAA
+
$(!)#(&''"#)*(""+%('%"*+'#$'*%!*))&+('#!!$!*(($#&!%*#&*#&'!%)"((%
@r8912
TTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACTCAACATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGTTGGGGCAGGTCTTTTTCCATGTCGTCTGCCAGTTCTGCNTCTTTCTCTT
+
@&A;!58/7B*D4/90-7B%HF23G*;/$'=!?+E,0111>:#7-(4?:33D)+HCH')&+BB7),=7)7(!AF&9<EDH1&+/51=CH;--!6*-!6C#1F1:3152.?6%0=<*F'G>/F:&@.$(94,2DA;!.<!'(9'6-=4>/)C<$65=-G+7+'7C(54=,BAC""#%H&:H4%"
@r8913
TTTTTTAGCAGCGAAGCGTTTGAGAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTNGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATANCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAAT
+
.+$F4&74*@@48-$+%>=F-G1CG01>"$9.")'-;F9><1/0%;'%;&9)9&?6..&(%E*DE$!()51GD%=);8$'#;*#809%*D;$*B7@*H=>C,@)2F#3H/!C(2/"$CE#$=/=!2E&.5(A%3C//*3/.?H,C2;+C%,+,#%"(064AD&>G,">/=8D5@:5#8<81)'=;4/1.?$4$F<)177,0<$;#!49H#)@,,?G7=#H46F4?2G<2@$'5@(<C<:.D2'8HE4,).F5C/'"0/'6C:@!D@B;A,B&><!>E!H@B=;D=B*+#7=<=D>3"=!5":')F!=C#E9CBB0H"H.H-*C*+E4..-
@r8914
AGGGGCAGCGTTCATCCCTGAAAGGTTGNCGGCAGCGTGCTTGTGGTGGGT
+
0+(G52?8>,23B-%*)&''2D=47C&7D4@!210+*A9C2#&(?@/-+::
@r8915
ATGAGGTTGCCCCGAATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACG
+
4#4==H(1!"-8C:E+A6"-)!+-8/G5+!#(8+C</@&G?1713FEC,>4<3,%B*;&9'4#0:C6:3C"AA<--(H"8,+6"
@r8916
NTANNNATCTCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTNTTAACACGGTGTTATCGTTTTCTNACACGATGTGAGTATTATCTGTGGCNAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAA
+
"(*$#+"!$(%+!)!+!!#'#%*$"(*%$#+'$#&""%()%%+#&"#+(#+((%%"#&+"!'*#'#!*(+$*(*%'%)!$(#%&+$$)%)(*%!!"+!"(&+!&*"*$'''!%&*!+$)('#+*#"$*'##&!$'"*#+!"#))$)&#)*##!#'))!($###'#!'+)*'!&"'&**'"''#)&)!#(*%*$$)$)()++#!''$#)")+"%#"$*+#!&!(+$""$'%)+%(""+*$(##***&%$&)"&*%"'"%!$%%*&%$*#
@r8917
CCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGCTTTTGATG
+
7C$<375A.C4%?%"FBD"'+189+E+-.#5#*F(<'H'5)-
@r8918
TAAATCCCCGCGAGTGCAAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTC
+
B4:$@A?1&FC%;.)0;-=G<.71"HE/8-EH#G<9&(HC5D'">:D$<*HG2$;,6#-6F9("4?6&C512ECD,B9:CG4%=1<$%"A!E=5+<7EE=@G";!?4+55*HG&FEG(+6H,($07+$";6GF>DHA,*!HE&:GH5<H=14#!,'=(22F+1"@A+*<?!%B2/>D/"A25&/2E33?;%=9'&#9*0):,GH'H2"4,#$&;6+,:D1?=&-<*:C(57$=+$AB'@)4
@r8919
TGTTAAACGGCGACTTTAAGGAACAATGAACATGAAAAGC
+
:F?#4B4"<9984/00?6??F<;A:8+&CC-B?/6),<F3
@r8920
ATACCCAGCCTCGCTTTGTAACGGAGTAGANGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCNGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATANTGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCANTTTTTCGCGTCACCCGCCACATGCTGTGCTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAAC
+
#$D155>(*0.9324$866C12/)<9'E420D#!DF##G.2&-1=',9)0H<323/?)GA46%!$)E-7'G<9'%%*/+!!-))&-%#<H7(?0.=.(1C;)$E:62D3!,2B/A"G*1)33@8'6B((7$$:(H&B$98?4*FD5'$HA,8BG,>5C"4;&7A&*9"<#8#>6!3!D1,E;;.39'-:2:C:2'DD4G6)>6@"F>7CG,?2EA:!)*A50(H':3;4*!G$/FA!,G58#53F>&?F:25((/):EC(/#6@+<*&G%G,;!:+.DH+5486B;'0*/F$9=F<,(!-'8+%G!H47$=:*!.C42F"
@r8921
GTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAG
+
*+4##G<,A8',$/&%G=$-B3(2-C9>/'C.;8"49C1B(F53/'HA>*(B4#E='#.#!8!!#G<7*H&F-.C;B,(G!;48F45611'D9-A-
@r8922
CNNNGTNTATGNGCNGGGCNTNNNATNCGNCTTNNANNNCCNNTANTCNGNNNANNAGAGNGNNNNNATGNNNANCTGNNANNNNACGNNNCCNCCNNNCNNNNNNATTNTNCC
+
!#!!##$$$$$#$#!""$##$##!!#""#$"$!"!$""#"#"#$##"""##!""$$$##!#$!!!!$$$$"$!"$###$!!!!"$$""#"!#!""#"#!"!!#$"#!!$$$"#"
@r8923
AGNACATCTACGACTGCTACGACCACTGCATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAGCAGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGNAATTGCGGAGACTTTGNGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTNCGTCGATGGGTTCG
+
'*$'%+*&&'''&%&#$*+%%")!*&&($'*'++#)#$"+%"&(!&))&!+'%(&!(*"%+!$&!)**"*'##'"+!)""&(*$*#!&(!*'%&+(%('!+)%%'%"!)('!*!+%)+#+'#**&##*'#"("''++)"$'%(%!$#(!&$&'!$+"+*$$)(&(+*)+%&('+&#(!!*"*)*%*##*")#!*%&(+"('!!&+($&'+(&!%#+%"(#+#'
@r8924
ATTCCTCCAAACCGCAAAAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACNNTTGGTATAACAATAATGTTAATGAAAAANGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCG
+
0.C<H21$*$4@+4DB=98$+/8@-'?-3,34A5G9:HBD0H7.:=7-7#0(4@H#42&8,&@,(D-)@2'F@HA,F76,1G05%A.;?,:;<F0$$5$,E26)&)1!43<A#D7&>#5=3A)'.>$3>0=2(C4&D&=>"#<<*94E"7#E.>)'.:)<6#!<
@r8925
TTCCNNGCCCCGNGATNACGGCGTTAAGTTTNCCGGTAACGGNCAGAGTTCAGAAATAAATAACGCGTCGCCGGT
+
#'$'&"!(*("'!%%("''"!")$&&'$&"("#*)%'&)"%&'"!+"+$*##)+$$"!$!)&)++&%)*)$+)'(
@r8926
TATCAGCCCCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACC
+
@D,$>2"B/1F(4E4-/>EH7<-1996&"7#0!7?#:<:A$8A($26=3$9<,-"$/A"-C3
@r8927
TCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCNNAAAGAAGGCTGAGCAGCAGANTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGNCTGCAGACGCCGCTGGAGAAATATACCGCCCGTCAGGAANAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCCAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGGCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTT
+
?6-EAF/G76*634#*;(:3*0?G(4,A'HGD8>.1F25B?)8:C#:EF"H'%;'0'F0.%!$:/?'!-?G>*'DDD5$):!-B7$,<(26*6+;-;0<E?1H%$'5G&H3*BFAB3#;!,;%;6,/%4:)%$7#1$H*/E8.4=B:D/5>BA<HA68G"%H==D2<(H@78=@4F*)C?/2C95B,2<5-7.8"+/+),C6B(6.E=4635F#.+>).G#*!8212@@>4@A6,E1A3&%C!2*F9$-"/3:*A=91!C#B5%<$7?7?H9'@6.&6;<;A3$F"H;'12-&1!:,F&H(<)6-1?<CF<%@1*;>9/*F(8G'EC>4.1&6,D0,?<+)C=#$AA5':%(B-;"@$7)@38H@==A@"@09D92.@//AB:C0'A9(;5&E8*:$':5:/";8!'D3,%@7FA
@r8928
TGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCNTC
+
DF+,$&1D-B*H/@(:++<,019/B?BF%(49%G40<3D@;=C@1(,>0"?%
@r8929
ATGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGC
+
1E>$AAE'61;#-/1G-4B20)306A:$%:)@6<5>G>,.89F(GEG%=46$2$9-(;B*4."0=D8/)%6-G(?1';E:-&
@r8930
AAATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGAT
+
(#+)"%'&'*+(($((!#&#!")*'%(($")$)&!$+%"(%)#+$+$"''*%+##'&+)
@r8931
CAGCTGGGGAACGGAGCGCGTCTGCCGCGGCAGACGCAAAAACAGC
+
4@A58(299,9E'=$"==2&+,8B4<2<B4:;7=EH*E#B.0#:7:
@r8932
AATCNCTGCATCTTGCCCCCGGCGTCGCGGCNCTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCCCTTGCAGTACCTTTGCCTTAGTATTTCCTTCA
+
(A(4,B16H+"H5,A=:(;,&H7;')%!D;)D>+80.:+DG8CE78/D4=/@B6$8((4$H40-7C%0%9#?$6;%!*D9<&6#G,;F-*H"=)?&17E25
@r8933
TGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAG
+
>"7!:;2(8G34:?@-''97H4C>0",8##'BGC3>&5?&
@r8934
NTTGAGAGTTGTTCCGTTGTGGGGAAAGATATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGG
+
"$$+!*$*+*#+!!+""($!+%!!'*))+!&$+&)!#!#(')"+#"$+()'(!!*)%#*$+'"%")#""("%&##
@r8935
CCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGC
+
86BEG/B=30"30<8F7C,#60"*6*<"1.G@$F#-7?8;6/'5&.&D*;C##*/7B<G"/D$-16G)D26-G"'C22450
@r8936
CNGCTNANTNTCTCGNNGGAAAGGGGGATGTATGGCCANAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAA
+
$%%((%$)"!#&!&$"'+"%*#()&)(*"""+&+$#!%#""*&+&&+)((%#$#((#('(&+!((")"%((&**&$"&'(*'$#&
@r8937
GCACATACGGGATAGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGG
+
(=086B(::=#5D-);:+&G4!3#0"/969*#47,$)C8;5,'!>,"3"'25HE.9'>A(7&C;"G6>GDD1D(D=4?0B,"%:%D&=H408,#C)8#=H+%->+
@r8938
TAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTGTCCATTGGTTTATT
+
8".A42%+0$$('8D&77DC158?0<7EDB?HGB0'>"68!65'-D=5-GB,1:<C##:=(.5;"6A75./4
@r8939
GATCAGCCTCTCTCTGAGGGTGAAATAATCCCGTTCAGCGGTGTCTGCCA
+
58)+!F1C@/*46&G&%/6F;?D,9(1:A<=!)'265<0-4D8>&/;<(E
@r8940
CCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCNGCTCAA
+
5.G:C<'!CF@H(*593'4!B#D)''CG"A40@7G#!.#:91
@r8941
CNNNNCCNGNGTTCGNGNNNNNANNCCGNNTTGTNNTNNAN
+
!"#!!!!"$!#!$#"$$#""!##$!$"!!!!!"#$"!#$!$
@r8942
AACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAANTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGCAATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGG
+
&;$$9:#()7"@@HGG@H>@/'<3"A544.B1*&(+:=B0,9+BE(*#!0>8<=1:#+C402E%"##;@G=D)&"&BD=*!E1(27C(7ECD-8+777.-+.6:D*CF$6F6<"%6($#@2642:4'EAF+>;:.4#>.&8B:)0>#@CB&4(,*"9D(33="7.!->3>-7AFG!*)/3.'-(>@D.""+5)@'+G''<*1?%4-:<*8"2?D*&F;?1H'3,'"G
@r8943
TCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCANCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGNTCAA
+
3G+6(A26"B/!@*2>'=)BG9"C;<,-=:G:8%&7%(<*EG)&*1F!#D=H%D#4G5G,H>?9>C7;CC=?#=HH?9<0:@/?2A:($A9G8/#20%.7CA#'13(+0>0&7,?H!!>!3(A$@28>8H*-D.,F6)D@(H-!/#,*!70C%?>3--=D>34*?,59F"EE7606/1<93/#1E(=#%@+("%:#%-</'(9B6C?,A5G&@?%HE4"--,..-0D,%,'@.5%84&(03:41)G2?&=H2<*!+7*9@/)D47>#(<,D.#9'!!1/086,E9.>673=3C&D!=!#)3&E766>!1-F?$,?D2'=E7EA.C33*"/
@r8944
AGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGNTGATGCGTGGCACAAATTACGGCTCTGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCC
+
+(+(+*#*)%)!!(%$+#)"%!%&'&#)+*%(#"')'#+!)'#$'))+##)"#$&$$)+*!)$'%%$%#&&)&#*$&!'"+*!$%#((%&))&(#*+#&(+"$%"+%$+#)+(+#&"!'*&!!%+%#&%"')(+#!(+!)'#**+"**'($#$&#$*$)"#)*(%+*%*'%*)$!'"+"$
@r8945
ANTGGCGGTGACGGTAATTTCTGCAACCGCGGCAAACTCACCATTACCGGATACAACCGGAANGTTGACCTTGCCTGNAGCAACGCCGTTCACGGT
+
,FF$=(5+"7)-#54E".DF"G<7G@=$$;1+CCF2*+*3ABA8%.H9G5.)B/$1;<.31)1(9/!7B;:A",C5&!00%D&.H*B-,1E"?/&6
@r8946
GGTAAAGTACAATGAAATAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTANAAATAATTTC
+
9<@/$9#42?>6;!G@'";G589*8$<2H+",(9%5">"@)&F0723.'D*@).<33EC,G'5:.'71+#>/%#@&B1G,!%16@08FHH((;6-(D-A!+#*:
@r8947
CGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACNGCNGAACGGGATTATTTCACNCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATNGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCT
+
<B;:'214#7C')+C"A5+"6"+/F-2;*)43B667"F2F4;+@.F-'FB1C'7>$H8/0;=3'(55;0F$.%41D5D,$$6C<A$'D&(!&0*""45.(DCF4?@@">D#0?>@$?#-.+'G2@D<F!23*A/?-:563CA<'A)?3>D&*.>C,C-+#>99&)-A)D**-:&>#3BG-H6#,@2)DG%-E=5)*@??7$')*@(?0>55/6)!EE?F$';C42F*#B=;?/9@4(E"-)B,H63*5%HG38-(B/3>
@r8948
TGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCNCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATGANTCA
+
0)6&AB93'.,A@=)<?5"!%423D&9?@&)%&;)556&&-C!#!#+"F*1;,52;+-*8,9(?!,3:2C4A-?D322#.""4&&'6-C.+#0!&AA<27**7<?(B-'$;17"B/5A:E6)=#E6=%650<G&(?&=+"46"E?F(D<?#%64,@9BE;4G!0?*%(-
@r8949
CCACGTCTGAAAGCGGATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATC
+
*!A$80<&C*77,;:*64A55C1C+=39=7:(+4"8?0EF4-C':D4H=0<&-E0F1@2;!)7$-4*58H2)!FF#D=B/)0F'4!$4C<@F@E&:2.2$"A9@:&)?@1<<*1?G<$1;H;79=+;A;G9321F.C)%&1A
@r8950
CCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGG
+
+'$!"$'##!'%)#%$"$)*#)"'$#!'!'%%%#*))*$''%*'*"#!%"!)+)#)&$*'%#
@r8951
TGTCCGCATCCTCAAGCGCGACAGCCCTTATCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTANTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGANGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACT
+
000@"C/,*1&C593;):5437!36)1?!7(-#+8@6G;"#G3>GD4!<G%,%;D02E%7,4-@6?8C<2?D39?1$>;*'3-37!7/;%12D=CAG)-)?*)F#*D@=:$+>4#&1*+*#(5F09;?0?7-%:'F*D+B"9B-766=3D&1A@7DF->9D<25F29
@r8952
CCCTTAATNTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCGTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGAAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGG
+
&-9:B@C*)=D4.%D>4-5!F:C4G@@/HE45=%&<'/%0;,-'6*F7CE<'@'B@+8B?)'B/?@C54GD64)H77((%D9#@:=%:$-A1!':C571&+HFE9?42A)C@B:5)F7),05!&+9G:=<>&<#@0D3$5'0#$&>0/A8A<+10,:'1,?H!G)H228:%->
@r8953
AGAGGAAAAACTTNACCAGATTAAGAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATG
+
C-!G4!+GB(E$.*%/@#/!,3;6+49)4$"#./AG?9+916"'('7)G,+HF04=1;*.'@@G=*H&%<8&$,+*1"D,@.>,%4.D35A?.@
@r8954
GGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGNCACGACGATGAACAGACGCTGCTGCGTGTNGATGAGGCCATNAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCCCGTCTCTGCTGG
+
&)%+((+"*(!$+*()+$!*##&%%!*#"!%$(++#(($"(#"!&+)!%+($"**"+!+($!*+%&#!%!*!#)+&$)+($"+$"$(*%'##)#!&(*#&(!!""'"*'"!(*"$"&+!""#*!%'#&*+!"%%'%)#'+()#'%'&("'%&**!"*)!+!
@r8955
TACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACNCATTTGGTGNTCCGGTTCTGCTTCCGGTATTNGCTTAATTC
+
;3+.2DC<,(<9;$"11=&,AAEC!:9*?450;FE<D<A0D:?/@*&)>B$(7AA"'C)6E4/G)C1@BE%!D/.=@$)8H7"AB932--99
@r8956
CCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGGCTGAAT
+
)E37D6#.9-;FF$5C)(49$;><5<B-A.8-57EF&*GG9$E/'9-G>
@r8957
TANTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTT
+
)(+(!()("%*'&#%$"#*#&)*($('&#%'*+'##!$$!($!
@r8958
GCAGTAGGTGAAGNCGGAAACCAGTTNCTTGTTGTTCGCCANCCTGGCAAGACTCCTGTTATCAAGCNCTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTA
+
*!")&"$)*('(''$"%$%(+*"$$)&(&%))*")))##&$&'')+&*('*)##*"(+*(')*#('+$"!#(%%!#!(*%'*+**!"&''%#!$*&($'&&&++$
@r8959
CGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGNGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCCTGCTCCCCTTATAAACCCACAGGG
+
-E6+2BCG?(96BD"@44$>3&7%+.>>%4*!(5D>.8;6H9"!>E7?=++.$!1,"7#4F:$'?6)*9G0%E6$6-9@;A'0=?("A/0(C5528>;+.A*5F)7&1>414BE89'8%E-A"CA3(=?>*6"*A9&8%'!:23&5A,GH'<"3F'+902;!7<G037*0G1%7(2)&?(</A-:--@1%;#%=$11GB:9E-)#B'"3;.<$64;D'?A%<E70CHC!<H3,D/2@=;/?B07#/4"+E:%4FAF,9)3))?!!%'@D&*((">4"%3*E:'!5B1*,D8C.&4E/"<:2"?@6
@r8960
GCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACANAACGCTGGTCCTTTCCGGCAATCAGGNGGGACTGANTGCAGATCGTATGCN
+
/581E1"/;47#%"B,'+$7GC3'9"@>B/+%F#<GA+7?B)6)B50#(*/7H5F=@)HH'B8&E6*"/DE*"#FC"?C,8;:45/FG!.;,(&*;'7
@r8961
GGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAAT
+
$C8.%"-2:<6,%'"27"',(0F89+##=F6/@0CG38B(.#'H2F.3!")58%D3,2.(>;5$>+A>6A3>:("?=+1HBC(+H8?'>40
@r8962
GNCGGTNNTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTA
+
#!"%&*!+$*#&+&''*)!+#&"$(&$%$))%*&*$()(('*%!'%*(++)!!'#%$''%"'!++!*''"!$!'+$&*"&&(!%*'&(!*!"&&$'#*!%)'!%"%#(%
@r8963
TTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCAACCCCGCTCTTAC
+
'/0150(-,H@63,?D-.70/+"1"F7<76'"&60140=:-:8/+2=/8C#
@r8964
GAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGNCCAGAAT
+
C9/F9/B#,<#7;@*6441@>*@%.51#:6*9/?#7(71-"C1"6?H,/+1?*,"AC>;<%;'";H.+?<<B&388HB"!A"G$D;/*8
@r8965
CACGGTGAAANTCAGTGGTACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTNACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAA
+
D%@1*.)";"8(73273CC(@&=*',57$8(%'!;,@:*=?.B,FDFDFFD+'*;0B#3@$6C36;<C;H(:!>B2G*@-7%->B<("AG@B>9/@3+G2/E"A1<C&2*()/E,()'&744.0F7"C-$<%?60E$G251.6:C2B"@*"-1F6H#
@r8966
NGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGNAATTGAGGCAGCATTGGTGAAGCACGATAATAATATGAAG
+
"*2C*"80%@--A:/2A#;#%='9*-;G'0&-3!F1*E0<.@>&&%<@4!:48!&&.%7?3AG(&.!E/*,"0#38(58D,A#20*/3D%4:4#
@r8967
ATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAA
+
/+39+0&E'?:<!59':%D@?A&)5<3'@/!9'13),?>',@B!!2=&"=$@+))4.;,"H3D#47>0B=*3/D(B9ED+'/5A0.?@30'1:56B"")6(8$@B2%@
@r8968
ANNAANTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCA
+
(!*&)#+!'*%%'$%$#*'"(#(##*#$%)&"$"))+#(*&!"+&#+!'''+')$$&''"!("+&
@r8969
GNCGCNANATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCNGGAACAGTTTTTCTGCTTCCGTATCCTNCACCCANNCTGTGCCGTTNCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATNTTCCGGTAACGGACNGAGTTCAGAAATAAATAACGCGTCGCCGGACGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCNATATCGGTACTGTTTGCAGGCAGACNGGTATGAGGCGGAATATATGC
+
*"*&&")!+%$#$!%!+&'#&!##()$%&$)#%)"+"##"('(&''*"'+&"+$#)+*)+&$&*"'"$)"'($+$%"!++$%()$*$""')!+)+&%'*%+%!&$+!&'($))%!%+'&*))%&'"+#+("*"!'+'*%(%!))&*!!')")$&(**#)'**$%+*"*&"$(%+*%%*(('##%"+&*'+((($*$*+!*#'(+##+$+""!(!"*'(#'&%$()*!&!%"!!$)%(#$%+%%&$"$%"#"%$)%&%&"#*%#**)(*%%!#")&!$"+*++))*)"+#*%')##"#&#"#"+"+'($&""'$!)$&&++*)##"+*(%(&(#"$("$!&&"&"""!%&"
@r8970
GTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGT
+
<B)7)2C=*)#B7)$%23+EA3C8=/"<&@67G3E%'+B.6B.8<B"DG%?G#<34%''(+F=@-&=GF8CF4,>(.B0@
@r8971
TGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACAT
+
(G@$3:)BC<%!*%D5!.G:!28G2!F/+9+HE6)6B9>E
@r8972
TCTGGCGCACGCCCGGCGANGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGG
+
*6EC7>34(5.45DC)8?>-D;!G778D,%DE2:-3"891AEE,&&G&)F,+0>+;4A-6,$0A#CEH
@r8973
CTGNAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTA
+
#*(!%'(+#$'%&#$$!$%(+(#"#'(%%($("*"!+&!$)%"(("'+%&+$!)##'"*$#)#(#&')%(*"&&)"#++(+*)"+(+
@r8974
AAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTC
+
C*%64=#=1D8BC,',F7&(!7AE&=@:A-%,E)E?B:,)"H):*'9(F><
@r8975
GCNGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGT
+
#(*$"&+!#*##!)&((+$%&"*('"!(")*'(&'$'%*!
@r8976
GGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAG
+
&H(.'.';#<<%AEH&E$B@%(>+1%);*8+03&"-510(4$*4E:E9"%<$68G.-#/7;&.6A:<>+/5#93:@$ECC;(+0G4B9@A143/@$B$,&'B6%A,9@<)3F(,
@r8977
TGATGCTCCACTTGAAGACATCACCACAANAGNAATTGCGGCA
+
,B6)/F*8@?A'&+,7$-$9-9"3)1=/.34/<)-)6>%6?.9
@r8978
NNATTATCAGCATGATTGCCACCGATGGCAACATCTTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTT
+
&!)++#&$&##!'"(!#)!*'$)&%((%*(!%#'(%)"+$"!+!!%$"'#$(%#)+'&*")&*'+$%!#(!(#)%'"*%(*+$+++$&"&((+&)*'(!&)+#)!("
@r8979
CGCACACGAAAAGCATCNGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCCCGANTTGCGCAGTTTGTCTGCAAGACTCTATGAGA
+
@"/"4.G1%6/18E7!4($F0--%F9)H/6.</*HF/*7+";BB=80'#G'0F5(230/@F>8.:#>E07*%=FEA-=&B@!6G80;9
@r8980
CTTNTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATA
+
(>@>:"=+7<CH2F%?%FF199/-""&+''H/H0?(5/.-!0:69%)/=,B,*?&/&D:)(',%-D"4F>32>;.@&7;124,>=E*%6.F#
@r8981
ATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATNATGTCGCGGGTATTGGCCTCAGCATGGAGGA
+
E1C>+0G//&87"#7$@20"<!:5=9+0-893(=CG61,DG:<4C>BFA).-(9<522&:<0/D1!6E)C5,,"$EE9>
@r8982
NNGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTNTAAAAAATTATAATNGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATANTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACGCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCTTTATGAAAATAATCTCCCAGATAAAAACAAACCNGCTAGAACATATTACGACGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGAC
+
%+(%)"!+)(*)+#+!''"!"'+%+!""%"!)&)()$%(*#(")%)+)+!#")'&*%'$(&+&#!)&"*!*'++)")(!&(&'#&$+*""'#%+"*#++$%"'%))+$+"!%(&'(#"&#**%%'%!*))%'*%&%%$'"%"'***+*$(!"#&&%!#&)%*&%%*)'%*&'%$*++!&)+"%!%"!#"&*'"$!%)#!(%%(+&)!$'%&&$'%'*($'&%+)'**+'!%$"!*&%#"!)$&("%!!$%(!$#%'!%+!++%"(!&)+#&%"$&)##+&'%++!!&$%'&$')$!%*(("&+'&+*%%$#))"&*$)&(()&%*!%)(*#&%'$*)(*)##++&('%#&(&#$%!#($&($*&&"'$(($&"$%#$)*!#")#)+&#'))%"*!'(((&*'&+&+"!#$)!%&!&&*+'(%%%$!"'*+&%&)&#%(#'#'(+!+&+##(#%+$)(#%%)$*#!)#+&*+(+$$"!$*+""#$'(%%#%&
@r8983
ATTAAAACCCACGTTGAGCCGACTATCCGTGATATTCCGTCGNTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGNAAAGCGGCAAAAAACTAC
+
(*"*)&%!$+%$!+$*$)+%$&()#'+%&++*!$)#+#&"+%*#)"'!'('#'$*'($&)&'&&&*)&&#$$&'+$+!!$%+$+'"""!")$!&$&&)&)!'!$('$*(%(())*!(#'#"&!$'&(%"!"!'!"!$#*'+$&*%(""("(%"&+)((+
@r8984
GAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCT
+
EE;6GA-+E*3?$(:F&E##?#%!F3)+??F6D@/DC;%1=:D0,;(5>GFH'4H;';/6A'169'/"BA9?;A.B$)91D7H+%0<%G!9CA.%H(?H2"G#99#7D?4AG&?A
@r8985
GAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGCT
+
,?!%+G"5#(96!%H->+2FB>9.!31$CAH:=GAD&:@H*4,$7%:3C;:</8@/=761""8<2(/23+2:HE
@r8986
GTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATCTGTCTTCA
+
.*1>4.H/,&2C7"<4F8AAH%B<#+7(36)63A@;4.E/*=HD/(H;<3,6=7=GHB;.1#0)HFC9;!E,;C0D<=8*@'(;?3&+A>3C4)=0#F0=:.DA%6D&6(>DH$/D-!1+6(G.))&$57
@r8987
CAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACC
+
H=G:.02;)2?@8>*1=1'/!?H-D302>73;,5;E8:H/+H5#/<3>(
@r8988
TCTGACACTACAGACTCTGNCCTCGCTGTGAAAACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTCTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACC
+
?C/9;03;EC5<.HA4G'+HF4H,F;5D=8)D/D,($."(<1-6!B5#8?;,1+",+8!#*:9&>:(35B66A/>'EB547C74G$/0D6BG93!F;*%7/,2D&H?@4!55$)66"@;),GD-53.AFC-5C+:?%5.6%%#"7.%1+&8DC4G"0C.(G2?$C'
@r8989
GTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACN
+
3)H%#H9D1"6:,;<%)<+"?=B)%;)?HCGGC19*'5?'(GB<5!32D+*'FG"H;"'.'%?#FB3">19D<.2;-0>(G=B.?=H&9-H04"1#1$/1$36C5D=C.1/2H!3C$5CE2.=G>9G81+;@>;+-5#6-?;/-*<-*4;H%2CB""21>>=))4G@=!81?!==1#+
@r8990
GNCTTGGAGCTTTGTTTTTCTGCNGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACGCACTATCGCCATCNGCATTGCNTCTGCATCGTTCATTCATACATGCATCCT
+
%$5AE2>9/F"H::G;:>6<$1/**003G&&5G;=$<B6,=*.4H7,%'F!:D07*0F/G#?C&,(H+@?);?'?&)FHA:H%-0CFG$0-3=H:?.HF363+G:F0EC<F+5F5
@r8991
AAGTCGCTTAATGTTCGTANAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATNACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTNGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTNGAATCTGTGGTTCATTACGTCTTAA
+
6A05F&99C"/6C""0.B"5!0$!9$F=C)A-1("B<;!!*=&9C"A';>45?1@4>(%=B4$>+!@%*B+*)>?73'4F2.%@@FH.D-E$FA0!$:'@+A05.'!?*9<G<9($H)?"5F$*(*#=DA18+=>%."'(4!%4-45E**/E>F=-/'<'60A"A(H)0,!('B$%>F'$E?@8=A@HCE,0B-FF9@3";&G'90@$23/@"=-02,G-FH:()&-16DCB3
@r8992
TCATAAAGTTCTCGGCATCACCATNCGTCGGCAACCAGATAAGGGTGTTGCGCTG
+
F)&D':+C3@=&3-0!24)-$%<3/'?,F:#-)!(:?(C)'H1?DE-7'$%FG5B
@r8993
CACTGCTTCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCNGCT
+
6*:)2EHB*6=;=G9*C5,885;B*/2+;/4&854%8()A'3:86C+C'
@r8994
TNCGCACCAATACCAACTGTATGCNCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGG
+
$!%(*+'!$!!(*'&!'+'&**!+%$"+*&(&(+++#"))!+$#+*#&$)%'+!!%')%##(%)*%)"$&%*
@r8995
GTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCANTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTC
+
->??H<5'7;H-+#B5(:67;+02"F4//**0-54E+037(.;+"=+81G8B>8$91#12=),2*GE5"<8.><+86HA@:HC9:6*(%1=!#90@G(&%C*'5E$2E
@r8996
ACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATA
+
H>$6!;1*4%-D2C*>,)B,/#GC%::B("H2D%F"-F.>;,F;;5AAF1+2E(>E=+?@F+&7+2&!50?D=41D.'<1BG/G9'B<?&2.#1EB$'#&A"<)=.D<:9E)6C6!B!A0"*28&5@156=F)B""(;D9'C924*>+H9#C76F4D=3GD)?-,93.0;4@&1
@r8997
TGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGANTAATCGTTTNGTGATNTGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTTAGTATATTGTAAAGCTGAGTATTGGTTTA
+
5"#1,9-35A$#34"@=HG0E1/:#)+)-5HG;9:=7$24<5"DAFH0+)1=4#-48*DC!:/6<*F03G'5(?/</*8-B);!7".?4?F-=@A9A.4+4%G($BB,#AF"*4"!;8B100B&B,6F'!;BH:)H6F0>/&4E/DHD;B5/+&'
@r8998
ACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTNGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGC
+
E#7E024(D80<1:6/?@7D5EB32:@?+?)"F3<(5(A09G&$B$0$+,:C*A$.,(G2<(HH,!(CE@:#A@
@r8999
TACCGACGCCGGATCGCCCTGCTGCCCTCACGCATTTACCGCCCGGA
+
,2)0(!!CH%C%)*@9D5?-6#(@G:!-:?F!3'A0@EF+ED4,'0D
@r9000
TAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGTACTTGGCGACAAGGTTNCGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGAC
+
/2,%5>C:>@#@5C<60(>&;%8;.=;0"HD$'.*,#B.5CB!C>-H!C=(':0%E2"()&<,%,?4C,.GC&;"/#CE;1()!,9G()/H-HH52C=$CE,,C/H&7;B.E&=@?%F!6B+@40;C#"+<H>)2<#92,#-CHA+=1>+6E$1/>.51
@r9001
CGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTNTGCGGTCAGGTG
+
!+'(+(*)"!(")*$$($!#&#!&&$!+"*%$%+!$'($*+!"&'+#))!!"!*'%'#*#+'!
@r9002
CTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCCGGTAATACACCGTTCGCCAGACCT
+
!4B58H?C=/E5HCE9DA97904*/49&4E+)(5:-A)G)/?'1?80,8)+=9).*
@r9003
GATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGTTATTTCAGNAGTTCAGCCATGAACGC
+
@6,5#-<F(<:,9/6=1B*CGD*&<?E7.+>'9<'=/A'F*(5/2A*C03D!?(595B..08@<+B-%8+54G+9;C4>G"?AD9H.B?:18?=,2C+69!+<#:
@r9004
TNTNCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCANACCGGTCTGCCT
+
*#$!'&+(&$%!())%"!)')$"*!&+#%)'+*&*!"&(#%"#%!%%&"+!((('()(+'#)!+'("+($
@r9005
CGGTGGATGTGGCGGGTTATGGTGAACTTGCTGCTTTTGATGATGATATTGAACAGGAA
+
5A9C;5"+06>8/:24%E527=6,":@/!F<3=66/';&=<9*;+-5'H9FF<!74#8B
@r9006
GTTGATCATCAGCAGGTAATCTNGAACCGCGANCGAATCAGCAACTCA
+
:!/<$%9@1/C/A?0@<)-$A3'&5"2*5H,@?=*@A<AH26="(25@
@r9007
NNGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGNCTCAGCGGTCAGTTCGCCGGGCGCCAGGTCTTTAANTTTTGCCAGACGCGACCAG
+
$!#&++$)'(*+)$')*+)""*'"!*("''&"!)$)))*$#"+!(+!'%#$')+)&**&**)+(*("&*)!+()$"&$!+#('"("*'"'(+'("%!($+*%+%'!)
@r9008
NATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGC
+
)-,.H,*E#062:;'G#@$H;=#G4B+,>A>++:?$$%F3&(6)5?F1!B75%G;CHH"!$:72>>8$G!C:*,$-1E$?%6#81E5#;HCA)D,&@?@=!+E%3
@r9009
CGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTCCCGTTATCCGTTGTCTGTATACGGGGA
+
F)$="/=;9G54G.FA('D5$C/5=G)*730C&7DA$:4$+#*E,A3(>9%;9/(19%2&+@EBG$58GE%"7-99'C85%DC'8F)1+&,DF17/DC,B$.1+'85B7>
@r9010
ATAATGCCAAGTTAGTATAAAAAAGCTGAACGAGNAACGTAAAATGATATAAATATCANTATATTCAATTAGAT
+
:%$*1/5?658E/&H0$"/B/80>:9319,%.GA6AF&A/&/0>4*<;,*-8F$,2(FC.CG19#@F<A8$(/0
@r9011
GCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGAT
+
-@4F&8$D+E9<C61?2"%G7*2:)CD+EH"!844C6G.?,A%"*9;!"&&G@0*3B5!)B0*9")AAH0FE9CA%2?8;?*$+%7>A+#<38>(G
@r9012
GGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCT
+
:<1H(:/6;A,A3B>EF=G9!.>$@%BA8*;(1:=8G>;%>&#C>9(A$C;46/%1=?C0*G(.*/+(D3FG:9.:5(B%8<3H1@/3H<"D.=$2GE2((E/)D!.9F*3%:<$7'-D.+CF+E/2
@r9013
NCCNCNNNNTACAGGTTAGAAACCGTCAGCNTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCGCCT
+
''"#*$!&*&(+()**+*"$**(!*&+(()&%($%)"'"%$)'$&+)!+*%%')%+%'("#'&(#*&&+'#%*''()#+&)*&+()(%#"(!"$)$)'!$%(&#!(((!!)"'%%))%!'$!%)&&"%*
@r9014
AACAAAACGCTGGTCCTTTNCGGCAATCAGGCGGGACTGACGGCANATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCAGCAGGGCTGACGT
+
*>@F)"6,+:+-97<F<*8&0255@-D<B(AG%95?97<<$:C714!.*%BBA"-.1>@+E3(C7#9G0?02E5%B%E5E/BE4*D'8(H%H&)
@r9015
CCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATC
+
87/A8@>%45CE:6/+>3'383.213@2)+7D0$G;!$E5@(?C!7E95>"'->"C%,0&-/?&6E/,!8+7!E4-:E.7C,=?H:DA178-;F:=/&2-,(C(!2H3>$H+D9?+@=1:DBD
@r9016
CTCGCGGGAAAAGGCACGGGCTTCTTNCTCCCCGATGCCCAGATAGCGCCANCTTGGGCGATGACTGAGCCGGAAAAAAG
+
;-;*'@6?B=A,42#&D1+B$GB;'>?,04-'H$$B&!H:,HH*%!>2/A8;!)133,,'EADH/&+*2;:)B;H.5>E&
@r9017
GATNCTGACGTTCACGCTTACGTCCACACGGCATTCGGCA
+
##(!%%+$)"(#%&#$#&')$(#+'"!)$)!&)%)$)$+"
@r9018
AAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCNGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTC
+
8(#709#=,;9/""20"4#3E*B;-;%5?!-C202D24CF#H@:FH,"C!"-":51807=3++6>/,>)*C,-('??F@<1&'!<?4=3?
@r9019
GGTGCCANTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGT
+
68715<</"5=)2.<>%2*.A45@H!&F&?06?);(/7=@4,DH=H0<%C)?#H
@r9020
AAACGTGAAGGCAGCAATCAGNATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGNAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATANTTACTNCTGATAATTAATCCTTAACNTTGCCCACCTGCCTTTTAAAACATTCCAG
+
2?3C:"A1(-A0C76BG)<!-@=3>=?2-@):5,/-%*"(?;6@=G@CC5?E.73.+E/!#3-@=,3+A4&47H'<2%4-%(1>!@09G2@55+.9767AG=?#=$?*">0CC78B)6"H:F@=!(),7G0<*G;$"B"5D9CA=2!&:,H.B@CG.F;;>;B7<9,1,DG4)+5#!(7'C!-4&F@7=?9<508*G%8A=/;:H8G5-'#@8D32C$'H7-/4GG.?G&F;H&3)59H</:75B?
@r9021
AGAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACA
+
(&+)+''!&"!*#)')+&$'*#)!%'$%%'+%"+#''#*$'#*&#'()*%*$""$%!%(!!"&"+')&("'%('(+"(#("&&!##&++*'+%"'
@r9022
ATGGCCACGNGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGG
+
%;H/!B+7"++B6<H>-78H'662;&F;<:B82F?E?D(#/>,34,6?80C7G@D4F>"-86">C.%9F.D@?<1>B,1$G*&G1*9?.-1"9HF853/!6;(';EB%>G,#0B<'0B=9896?B2<5C:H+
@r9023
GTTCGTCCGGGAACGGGCGTTTTANTNTAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGNCGCACTTGCGGTGACAGTCACTCCG
+
15/E=$$$C'#1:;A!(,@7FC$F+@<5C71)9>-'B+%B#8H,&*)(-%@(G<(A419&CB28,+FE95#A>"),=@<F1-90937$?'B24++-H0"*21!8#*G+
@r9024
CATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCNGCATCAGAAGTAGAAGAA
+
+%CC7(>1/"G@6C$A=D:?>#,%>?@3FB(!)H13&?(#/A)#5C#6;"=G*G3!:F>8C#FB$=C.?<$!=(D<=0#/G);D?;
@r9025
TGGGCTGTCAAAATTGAGCAGACCAAAGACGGTAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGAGGAAGGCAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGNCAANCGGGAATGAAACGCCGATGTTTGTGGCGCNGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGG
+
$:,1=!4>D%")3G3+&0,5-)@?)41=G9F<D<<7#$1%$D8:?1(!"$.6A+7,><F>=.;#)'>,0!DC*2,?2::8'@'.6#9=-,:(;7D@98#%$30D0)GF.+#>07#(/>;:63"0="(FFF?0&+/C,:6)""2'(819B=&+*/E'++1CFA9)9>+B,B4;H+3-<,E&;1%0.%C'B*2BA$+GD#C4?FE&-%7H16#94.;E:73/9>@;1+6B7!0/H);)4="$:3+G/9'!'%
@r9026
AGGACGCCGCCATATGAGTGGCGGCAGNTAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGT
+
,G6"'>:./:@C9$?';:,BE<@.'>!<14,".+,'-B)2"B:964F2EEA1BH7-4=5(.E
@r9027
ACTGATGCAACTGATTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACNGAAGCGGAAAAAANTGCCGCAGCCGCAGAGTCC
+
-!840.@;57:F>@B?2#9D:&H5)FE?8-803<68E)E48C)>8*DE>5HG+8=E''4.C>C>?*!1+FG;-&/#=*7AC82G3)=>028-6'073$C!:C*;A41+B!H0F1,92BA&&(+5B&>35$B"F=81B;/#4
@r9028
NAGNNGNGTTAANATTNACTGCTTAACTGNCAANGGAANTNGAGTTGTTTGATCTTTGCAATGAT
+
"*#**(%&$"'*$%)*'((&$('(*')(%!)**#)##%'!"&''+'#!$&$+#)%#+**)*%)'$
@r9029
TACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAANACACGCTGCAATCCCTCCTCATCT
+
89D8G=6A5?(.8F>/,?<H.%&;#5#2>8;>"A.+/B#==(&A03G@(:G1#%G=*0H:09;>,F*,!@:?GD8,8'-44/;<9+7'B3=/#-EG7C:DF"C8'4H!!%098C0F301$1$#<G&D:8;-H
@r9030
TATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGNGATTGCACCAA
+
)'-G2##%460!C%B5F(E4@-A*-(%A,!*C&;/+"*%0>A45,&E#<%$1+33*$7.FF,
@r9031
CCGGCGCGTTTATTCAGCAANTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTG
+
;;7;/7"#>9@'DD-$=>DBD1GHAH/%=>H'4.,'>3C4E(G"#H;#/"01+.<+G)/.;F:)&>!6+3&)6E>:%<B3D&9D;*>(;*E"E@':E?*B).@9-@".B305;
@r9032
GACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAA
+
41!H>(<%02;"$AA!5;#"?=E9(-0,$5C@&@'43,(<0!*
@r9033
NTTGTTACGCAACCAANACTATTAAGTGAAAACATTCCTAATATTTGACATA
+
#B++52/*H06>00>0<?834('-:<9F;C%.3-5>5;G9,F8,&!--0<4%
@r9034
GATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACANAGAAGAGTCAATCGCAGACAACATTTTGAATGCGNTCACACGTTAGCAGCATGATTGCCACCGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATN
+
56=AH*7@)+.+@15)/F"B('D%.-%$G@F':.@<A=0";@')!)?%4A$0F(=:-:B5H&C2E108$$D&9"/&D>'*@0G6DG#2:1>6/.#0B:1,2,G@4?8@63!2/!8'=98,C4:':.&E#>3";-=H<""!30?*-48:(#>#F$?B1*=*65D%<!3!@0G%-!(H5$32FBD>>.7B"(:='E/5F*31<6>)+"27>8/H4%"&;:)#&G
@r9035
CNNTTCGCTCTNTTCAGCAACACCGTCAGGAACACGGCTCACTTTTACCTTCACGCCGTCGGTGACGAACTGAACCTCCACGCTGACCGNATTGCCANTTCCGTCAAC
+
%"!"!)))(!)"+&'&%(+#)+#%%"%%'(%)'(*'$)##!%*(()%"%$$&##)+**%+')$%&!'")&&)+++!(')"!#+&%"$$)+'$)*#!%++*'+&$"$(*
@r9036
ATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCNATCTCTTCAGCTATCTCAGCATTGGTGACCTTG
+
!A:93@)2%-30/05H-9/:43/?)/!+-F:.=9@9C-!B/;?F"()BG/=#&=';':E3/"=>4-*07A=,1?&33+?%/#:D7</G@@A)94%?.?8!"6&"+(>8(;<<D<!$0&':E%>9>7=C!8.3@:'(41
@r9037
ATAAGAAAAAACAGGGTACTCATACTCACTTNTAAGTGACGGCTGCATACTAANCGCTTCATAC
+
?(;+B&D4H)(B9A8)@6;B,)1E15?!CA6:D$;-%6;27E'$?$8?@%"!H#D-F@52*)$4
@r9038
TGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGC
+
!H<4&.&.<2BE(HB('$"@(&$%2;7B:3272-G;B&4A-;@?49B74;$:F.9,62E9/.7+GE2<C+223AEF,-.+)GE)#E
@r9039
CCCNGGANCTTCNATCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCAAAGGTAAAGACATAAGTCAGAT
+
*(&!&"*#**)%#*$%+)'!''##!'(*($'(#$+#)#*'&*+"%+&%(+%%(!+(+*($))+"!')%($!(((!"*('#"
@r9040
CACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGNCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGG
+
GFB,-3''=.<4>'>#=11=';D&2."?8"C5D#*H6<2E&,,18%&/;>+!)(5,/:8;E2?9%22=,:30(HA/H2HFC>2/$5:2CFE3#.('?H,!;.6"@=%/=;B+3)-B75457?95.@$HDH-(2>>@<9
@r9041
CCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCT
+
9+)3+C98;*C:@.,5F"?+H-/;5*>&F'=5"C).A!F$7&8G4'/$D&-//1B<:B)9
@r9042
NNANNNNNNNTCNNCGTNNCNNNTTGNCNCNNNNCGGAGTTNNCNCNNCGCTNNNGNACNANNTGGNNTCGTTAAACNNCANAGNNNTGTNNANATCCNCGNTGNNGAGGGTNTNNANNGNNTAGCNNGGCNNCCNNGNNNCNNNG
+
!!!!$!$#!"!"!$!$$!!"$!!"!$!#$!$"$#$$#!"!!!"#$"!$!$$$###!"##"!!"$$$!!$"$$"##$$!#!$$#!"!#!"!#$"#!$"!#$"#$$!!""#$"$!!""$"!"!!"!#!!!$"$!"#!$!#"!"$!"$#
@r9043
NCAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGNGTTCTG
+
!D:H+-6FG8:39$;,5;&/F2!7;'0!>B.H8-(188C$A<+?<,220(6E,$,,6H!C<F=F)"/D')1#E/$&5.&C:D1ED:/:C3A$$2@/
@r9044
AACNCNTGCAGANNTTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCNGATTTCCACTTTTCATTTAATAGAAAAAG
+
#%%!(()"#*)'&#)+*(!#$)%+$#&%'!*#)!$""'&!#&&%!*"&$"!**"!&((*'(*%"(*&*$&)(#+"(+)+&*"*"%'%%$&
@r9045
ACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGCATGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTC
+
9=H0G!<A:<G((/E(,#ADF#70"/>38B!)!83<*@6EG419.A>$<DEBD70?816"G@;EE6BC>'FA!=1*$=$G.E;=;@@1?9!64+H"(6BC%F2&9".?1B=0!B>D(H,E;"D>F:*/G<..01#?#+-1-+CFH3?H3*@4+>=F1/B1@G=@7E!GH,:"9E41-5&H$HEAF1")EH2C*0'++GD98*=G':0/<,)#+23%9FF
@r9046
ACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGAC
+
8(2(),BE(7@"+%B,B91683$'B:=6'(72B83)(/1HDD&&,1)A$+DA',
@r9047
CTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAA
+
)06*'-0+8?D+$$7G"9B>!(@F>7>0EA7BB25CH<'9F8B42'9$8@'1?D(A#%*8D<>H.D(,+*#
@r9048
CACCGGATGACGAAAACCAGAGAATGCCATNACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGC
+
44"D+H1=C3B-,=-@,3E96(4-G'19F1("@>B<6$>:!7*/)F'A5;",!910:6/3A)//<7$C7)9&@=82=',/HE,(;*9$0DE.
@r9049
TACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAA
+
9HF'(9.:""50$FG436%)6/4)3AHB318!.11*#A2F,%#*9!8(E)'-+'#<>,@7!:(54*@&8A<E5C.#
@r9050
AAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACATGA
+
48>313F10)1)A%)7B75B<>>##;7,*<%8?BE%"FD/*.>&8'=!E7!0!7
@r9051
CAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGNGGATCTATGAAAAACATCGTCGCACAGATGGTTA
+
,=?350*(+/53;,.,+4=+!E.F$09'?C*&E7,'E?<A8)H"20.8"'=**(G5F=/DH(+:@F1:4"!?(@
@r9052
TGGTCAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCNCCC
+
+;&!;&(2?4)"'BH#*F"?!#798-?),A-,986.1(>9,A?9+C.(-!$+#CF=;()$&,$:B47A)#-84A>=H@:
@r9053
ATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCANTACCCG
+
D2@FAF@@"#=3G4+F34.3!(+E0::F1&38%1><2F/,BE&.!@,%3>:
@r9054
AGGTTATNAGNNNGCTGGANGACNGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATACGCTTTCATGGATACAGGTTGTGAACATNCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGG
+
(&!)')#&%&"%%)%!%()'&%'&*"'(+(&)("$&%")&'$#*"&+)$'&$**&($+))+'+#!#&&"*)+$)*!)"%!'""#%*!")*)#)('(%**))#*$+!%$*$'#($*"!&"(!!!!()(!"*"%"&$+*(*&!(()$)*%"*
@r9055
AGTNNCNACNTCGTCNGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGNTCTTTAAN
+
"$$!!$&$#"%!#))+$*+(#$%!!"$++''"+((()%&%#+%*"%*+(&%(*'$+&%)*%$&*)%)($!%(*)%+"$"&&!##$'%
@r9056
NGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGAACCCAGCACCGTCTCGGANCCGGAGGATTCAAN
+
22))A(1?:0+()=<4$+<1($>5>:/F@B87.6?8"#6.8,,10()=&*G"F1816*#A('.4*#*H5&!7-!+&E)4<CGHC4?CDD.=##488C+D5-F/).G=9+*:?<AA$?@?#G)&>1@D=94B1F
@r9057
GTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTNGAT
+
<A!'E#6.-753E(?@)*6%/-*$'1--GEG8<-?%@4/HC!+,B$#9!#,.
@r9058
TAAATTACATGAGCAAAATTAAAGCAATAAGGANGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGGGCGATGCATTCCGAGAGGCAANAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGGAGATCAAGACTTACGGCTGACG
+
,0HD4683/:F8)H3$1H;<#2B#$?%7C@(EAE06A'+=.&C)-&&,B)'6/<H4-+'!!)E8DE)2,GE1&5:CA=&;0-0C1A"F$'F-43#DD1?,43@;-<7G0B'%(6;&BG(F-$(4)6,65+4:>=.2$/5@B%*9F9>E+"%E>E61<FH=)H93,56$'#-GA&7:(3?2C#!C<620HD0A/!%@AF.:*>B+0='0H#F71!,/E,1.9183C<9"DA%38"F+&C+:+A5@2G+H44&".<3&@:
@r9059
ACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGNGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTG
+
0BCCH'H2+.82%'1G&H;32@,"*-.:@5+8%@G-082);73F2&/-7#9E"$')>G&=<G=$E=G.C:8:@F348*1(E,)";D,%,:0.4)))?@BH-D&-@H+,7.(39%,%.8!F
@r9060
CNTNNCAGAAAACGATAACAACGTGTTAATAAAAGGACTTNAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTAT
+
*&)(#!)+%%"'$++(')'*!"%"(%()(%+)#%'((($&*!#&!&)$"++#&&)&"#!"))$$**$+&%'#$!+"*"$*++'+&+!!()$%&#""'
@r9061
ATTTTTTATCTTTGCTTACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGGGCAAGAGCTTCAGCCAGAATTTNTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCNGT
+
#*<<F%FH75.1B-5$*125$$?)>)@26H"'*+&@*58C6A%73!,H)5>&AHHGEG.E$'(4;758)'(3"9;&(=<+387.9?$*A,&:5!D>/7;E/$"6*.'<E3)8G3@.HD3A=G?@?F>=-
@r9062
ATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTACTTT
+
;8DC.G1%#@(AFG!3=#/4=5'A(:D,!E)59040%8+EG*3).4#3'?@'>A14>9FFF+&:
@r9063
NTATGTTAAACATTGGTANAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATATATTATTAAATCAGAAAGACGATGGGTCGCTAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTC
+
$G5.%")>9C/#%.8H%97&;"/@;E?F=:<B07'-3);;G,C37$.:C8+"?1"F224(!2;"$A$H9%>.)%.?B5;>3G;)E)<"6.'.(HAG)85:D3>;#F5.8CG>6;?HH%4E#AE#HH:1">6==;3C*=*8=$+"!D:*!A;,D/425@>=1:=.C4A6(!""/>8F?($8<
@r9064
GGNGCAGGTACACCGCGCCGGGCTGTGGCTGAGAACTGCTGGAAACGCAGACCGTGGATTTCAGAGTCGGCGCAGAAGGGCTTCGCCANGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTNTGCCGGTATCAGCACCGG
+
0,B!;',!=020/'*>8C5>,%0$04)@'?C>'&>**@1C2.5D9#+F+"2>31<8H5$!A*G7@.>E'7<E($)C=G01/$-://5,:;CG.*5-&)2)FC+(2&5DC2A68@&/C3G@H'B/(-/.55F1)A(0A&<,G=F?$
@r9065
TCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGANCCCGTGATGACCTCATTAAAAACACGCTGNAATCCCTCCTCATCTTT
+
3)0:=!-56,4A=0!G.'*>(<*%((*'-?$(:?7!6=2+*3902G6,*59$$B:2(GB2;H$.F360C5A$@!6;@@#6=&505+$F<=F@B%!A>-!,",5H;=9&3)H#D!:5
@r9066
CGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTA
+
C0=6G/))'6D2!="CEEH%2"&HDH09">":G4#/'AH=;E3F7'0%*A>H2+4$"*3*G!(AH6#@+80=F7)0!+E1@8'7::"6/;(2
@r9067
TGTANTTTGTANTNTTCNCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGNGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTNTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATG
+
)&(**#%"*%$%#)+*"%(&##$!#!%"##)"&*%((+($*+'*$)%)!+%''+#+$+(%")(*!"(+!!**+*$&&!)"+"("#!)%$'+%&*"#)%()%*(&+#*!&&!#"*$+$+&*+'$(&"#)+#!%%&'!*"*)'(#'#'&(*"+$("#(!*&&$$"'!*('*&!)&'(*()&&'$#+!("('!+**)&+*#$%)$'&!
@r9068
TATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATGATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATGAGTGGAATGCCATGTGGGCT
+
4E1(%.B;--6EB)C7%H*1=.H4&+,%B@=$1%/59"?D'%-5#0./:,>&1&'-7HF9;9-7F,;#G@'#"$8&,4H/A1@&74$-/(G%":/('3:E'6+AG=DG&%=%D>=-G-*E**,$C;>47*';1(F(-HH693)3E*-HC9(C"8&9>C3E1*3>:2=?#?8?DB'0?@HA@905(08>/:A./:;$F3=+87.2=770@,50/#*HB>?053&:/B?B;H:.E/EED!)*E>=%B*'76%2A59::&%6:%-;A6G<2%+C/;!,"G&+!!91H.(H$>6A=A:&#9$.3
@r9069
CTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGACGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAG
+
0ACA!-D*3(7*6?<)9-!'%F.@G:<B8&D+?7!=*)))9!30E%&%)1C4H%CF2;6@H79@59H&:<)<68.,C$-H(14=&-%H$4<D$@74FA?9,)+5-//G1&'+17.'F=EE6"@0.(G35<$B..7H(>E*D
@r9070
ANNNANTTTTTGCCCAGCAGGTCCGTGAAAGGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCNGG
+
%'&'&!$+$#)!%$&"&*+!')"*$)!(&"'#)#(%'!)#%+(#$$$)+%%(&%"&%(#%&+#+$*%"+!+
@r9071
GGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAA
+
4,415%%75C1ED<2C2.#)7)(G4GC>FA$8'.2'&45:'2DG!8%B7B@?;&3BA<%!%.16(G+@A4!B!+=,$5"57C@D@:C"4
@r9072
NANCCANCGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGT
+
"(!$$)%!*)#$)'++#%#*#++)!)!)(*!*)'%!$!!$$)!+)"'
@r9073
AAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTC
+
H%423+4$09HAE0&?*('E'656!@?45CF7GC<7GC"G+-%.6.@A2ED$932$9:G'F3CD:A0$/
@r9074
CGAAGAGTGGTGATCAGTTCCCGTGGGTCGACAGAATCCATGCCGA
+
+'#)$%$$")++*"+'&#%%%*+&(#*!%!&)(+#(%*&%&*)!+!
@r9075
GATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGA
+
C@4$H=#7,$=*H%;2$GE.!2@!5&<1*$A50##EB@2G0%F%$*!&'EG:A+/F-DA)-<$763F+A27
@r9076
TTCCGTGTAGAGCTATCNCTTCACCACGGAGAAAGTCTTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTTTTGCCGGTGAGGTTATC
+
$<G"+#A;@5')&98?#1H8-H2==3@3D&BF,A&064!).4D9!7"7;,3/>024<H#1=/'B;B<B=4C>-44)"8H1%9+)6?62@GB6'/ADA$(G6%%(4>4:8A
@r9077
ATGCGACTGCCACGGCCCNGTGATTTCNCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTC
+
;@-7;+E,=@@E25646+C'#@1'7.F<:$$&,/B8#@59(G/#AG7&#%>4(!D10=3$5G5H'',.(?$/G<,0/H=1<8?EE4H16*?6=@%173$<4F8G?
@r9078
GATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCNCTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCNATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATA
+
5<<&H&1BG#EB*"&24&C9FA)$1=;<%@>A*)!;/1>,#">:@7,7F+/30F(5'/;(!?EB:/>B;'*<(A2;.'9+&H+#"-,/:G64!./E<#D909:$14:5492/9!831CG9=?,FE;H52:*C!7G"H/"2+33C8H*!"HD;!7CG/(?F5/!@E5.A,/D)?,$3@19CFG=H,E:#
@r9079
GGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCG
+
8G2H>78<8##("6<0:=,"=2$9>"*H!39%5G1:5%D3,FE=3$=<*7-9>6)%4-!ADB&,+.5$*C$*.F1/E'G9)H@/281A21C.#?G%&*?0793#(-
@r9080
GAATCAACGGACAGCGATAATAAGTGGTGGTATCCAAAATTTGTCANTTCAAGTAAAAACACCTCACGAGTTAAAACACCTANGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGACCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATNAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAANACAATTGCATATCCAGAGCTCATTCGAACCAGATATTTCTGGATATTGTC
+
1B#5.-'A$@@2$%@@=A"H#2>(@-6!F0HA@?*=D:?F%&'$(H)8?$,-GA!&G2C='+H75-EA4#GBECAGB%+C"@0?=/B.*A6;0E*/F<:DA>3&'D-!<4AE1&;1><'A>11""!,.=89D(B"2:0'F&*3#H,7$>"-<=66*4BH.5>;9?B,A7G@E61D1):#@+404$/9"5+5-C)*5!!'#:8GH-9(F%32DF5+%A:>9=1:76-$;$$"85/D)85;G."A'<,=G;306$!B("+GAB(:D8$07G+EE>*.B>'+>$#>"4*>487#8-%1=3=H09B*%72C-=C)04=H>',,/2H1>";@F=7*B7()-'#/>0(2<37*@,5,B2,&5E8"%"*;A5)?"02?67(""/>*?7-;7D>0";,=3)=%A2A,72H>>
@r9081
CAGTCCATGTCGGTGACAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAANTCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAAC
+
5'#CBF/9"6.AE-;1'+/0>4@396;8CH7GF1>;))$1:+@G8D;!=:86>A>A'"22>?G)C&>8=*B;!D1A;6#F'8HBG;"=)*B"EG72H%%B&9?F+/"!2!,!C:8FB:=
@r9082
GACGCCGGACNGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGA
+
0@)70081(0$%%F3+D7<H!+0-:%='.";!?!7A>,)CF/+/>-3+$2E<!/E1<-=/6/D9!BE$@64)E(
@r9083
TCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTATGCACGTCTTTACCTGCCCGTCGCTT
+
!+"')$"%#!+*$(!(+%#'*)*'$%+&*("%!#+(('#%))"!+#($(+$)++$)&**&&#++&*$)"'$$+%$')&)$*")()+*)%+#)'+%"*))!
@r9084
TACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGG
+
>9G>'-)./3'-.4B.&3D,$H!".8)6;*(G0;B+6EB$!59=D?/B15.83"6F#(8?4?H*-33C.B7.)/57881"!1(E<&&=95<2(7-.E-6D:%D-#7@7HA7>
@r9085
CGTGGTCCGTCATCATCACCGGATAATGCCAGCGACGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAACCCCGCGCA
+
FG=#!.4H6#F9:3HED7</;?+7(7%96&?&E'F:!/#E.".$8>,D*",-3-AE68F%/F/H$'A=A)A)2?=-6*CF4+72+0;>5?464+:-4'BH>)5#98D)&(*(01'-0?1776!"A%8->':AB,.
@r9086
CGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGCTAATCTCCTG
+
6-D(</68$*9GD2HDC'E&%4$(78F-0&/<9.5.45&C*:*2,7(,&:.+HC)6.6*84.?.1<,96B-BHF4)@=6!&>$<(?H"FB?7(9,$=$;DB'GF)B,C8%1$;"DE'4
@r9087
AGAAAAGATTATTCGTCNGAGAATTCTCTAGGCGAATCCTCTGACCAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAA
+
)H14B:$"H=GG4&>6"#<4'5$G"/357H;).=?#=3#/2?:F&+<@7/4B(&H&D;C482#)<F(*H*&)/;</AB&@)+$$?C=.3B$:??&&.280-6FAD465/",#GGE?2.,9@#&BH&?.B=+=7<9,G><51G8G&7G&1&B%?<049;!CA9,3B=A8&HG+?H19E)6?"=$
@r9088
AAACGGGATATCATCAAAGCCATGAACAAAGCAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATANATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTATCCGCGCCGGGCTTCGCTCACTNTT
+
F$,7C!=$.)?HG<*3';'1=.(E2/.*@)8-2.G#1:046?5"E75;B&2-D!$&/E86;%"%HF%>0/!49*-&3C@BE"55(%8GE+";#6F(,%;14:.6(22>+.1/.7<<3#C(;&6,G#$=D#!:':-
@r9089
GCTATTTCGCAGGTCTTTGAGTTTCTGTTNGTACTCTGCCTTNATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGT
+
87GH!!?B9-5)%B9-*E8:H4&H64&&B?=5-/BE'07=2;)+?*>57G:$?'D2;6:%%B!!4=??-2>D5A';GH"'/"H*B>9<41.!>/#,3EGB$$43B:;BFH9%&.8<<%E'G*4&1#=)#9<#:EFA6-5D;(;%?C*7F/"*F!72&7;*+"68*>(5B'@D0
@r9090
TCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCG
+
>D19G(3-%%&(89&C?499%*%2$7%3)4"HH34*1%'=$0?>F"6-FE/
@r9091
AGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCC
+
?+*@=',,H-69@$'7<FG3&46B0+@-4>:554DE(-#/=G27F
@r9092
TTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTC
+
7H%43H10'/=)3*B(9)D1?458*#5>CED7=&24!/5*5/0?F.B(.ABC2<6EA5AF?BF@9G./.:8E*DE%7!0B7G4@5C'GED92037-$5@G<:>%5#*-;E:6E)4BBF?@?A2-&B@G(.=;0)*4.!(3#1">
@r9093
TGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTNCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCNTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCCAATGATTCGGTTTTCAGGACCATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCA
+
?4):CBE?A/-),/?HF!H%G/HD7B,$F8@H##H+H$D--@'")A%A#68B30+GH:FCB>*<$AA7:55EG0'-1*5/!&1<'9B130EC$9::A*0=F.4+@"6896GFA>BG!(;E>G@C535;0/3"7+B6792H$4/A8(5/>@*44>/)&-;".6*4'7$=EE)>1).B$.-69':1*(84F2-+A79-A?G"5+<!"4H8+;!F4C,D%.@9?+$%*EG6-!67CEG81<%*
@r9094
CCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATNGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCCGCC
+
D&G=,#<?88*464$49G&/#%7!*8BD518E&9("**@+:%HF8/(G3,6@!"8D>?=98%B3HD@'!8#&(A$&#7D,(:!&A+!DFE))-<&@E%8&+';#:A79/#<@A=:5&+"H2&F!+@2<./6AE97/H4!48-H#F!7G#@.6
@r9095
GATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCNTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGNAATGGCATATTGCATGGTGTNCTCCTTATTTATACATAACGAAAAACGCCTC
+
-C739&?&C8)3H1<F"*,"0G=(A*DB!*3)GF@-84F(6=*)!$H3-151'@>04)?=3<BG9FD-E@?@;A:;7F.86/H!(3A2@54'3"D#>!#),6B!D1(15<G,8C3C89AGD6@E0,(G*20#8B7&&9-?/D$:B)@-,DE.164-89+7=&-CG+*+BG6$%>208>F@A*$'/>#A?C568!E0&7::.).<&75/.!$%1*;=?C6.:3F!-;7$G<!-37E3G""-;*3:%&""40>5?"1D8G,G0#.B'!7)G9(A-(D-E&1'<F+D56!*8&1/CGE
@r9096
AAGCCAGTTGATCATCAGCNGGTAATCTGGAACCGCGAACGAATC
+
A.A,!6+27+:D0B"C,@C65GG2$E?-8(1-#+3-GC:'".0;*
@r9097
CGGTCAGANTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCT
+
&AG>B9@?><9'G&D93<$#E>BA-+&&3;:)9E'$.@<.<)5G<
@r9098
AAGGCTGGGCGCTGNTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATANCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTGGGCAAAGCGGTGTC
+
4)'9;.39&%&C@!AC,C2BDG<+%;*-;7&-AG?,".8H+=:<8%D-2$05:"")D%;BH(&3%1<'7*E;@4+"A0*8%5C-51,8=H)!&*33>F54B>37G-#B>247
@r9099
CAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCNGTATGTTTCATCGCTTTATTACCATCCTCAGTNGATGCTGCAGCGCA
+
C'(0FGB%+0!)=H.$9?9/E@E;<%'="<>B0GH+%34!<B()=G$A0$6<G<;CE"9A&5E*)@0@'*;2(CB<(>*1.,8.(%0"F'?1+4-(%F($"%F<1"B5E)14985-"B%0"3.58B1!EH
@r9100
ACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGNTAAAGTACAATGAAAAA
+
?2&0+AD@/C-DE?2:/8%3.7A19>-;F&0DGD=D&072'7H)1<44>?.6AG6
@r9101
NAAGNGCAACGTTTCAGCAGCTGCAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAG
+
!$$!+"&*&'(+%%'*!&'("$$(+&)%'&(&'!&'%!+!#!##$*(*$%&(%+&$##)'%*!"%'(+*&($+#$)%(#!%+%&%$##$**((!)"
@r9102
TCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCNGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTG
+
/2G611'9?6!<4:7%!A<58&#77/5656&&.G47D>&.@%@.F5B7:%#7)8)(7BAB+=/E91658?C0G"3;$"044F9?H7$+$,'6A??8'%"FBB94@"BC";&D4=(7$.A+G:-2@<80'H8C*D'3*2+;!1"2#@92:=*0A<6E=<>$:6<D?44?&8$1D"""2.B!6$(*(
@r9103
AGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCC
+
4E9=2>!(08!7H7/>C@"5D/FFB>*:@-7?,D%%((D7<>D/
@r9104
GAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTA
+
$/3%"77*&5*#?%/?""AE!CE$G':8-5:>374*@*@06
@r9105
GCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCNAGTCTCATGCGNCTTCTCCCTGTACCTGNATCAATGTTAGGTTTCC
+
2H/2:%71&%AA;@A--..8B'/1<42*:.H/836-C+200=G/!=B$.B)F66E$?!/?7,-"&C9*<$638GA4F716!")*;%+-9"85<9D##&3,D,E:&%+<5?<G!8@*1)H,C887D7+D/1/!2.84+*"&(HEE1@&4F#B&%)%<3,:&#>3&/)8,&>>.(302&8)1:D3E6,>-F?E<@00;(;EF256G/B"-((72:4'3G!377;.+2!17%5E(9G)
@r9106
TTNTTCCTCGGTACATANTCTCCTTTGGCGTTTCCCGATGTCCGTCANGCACATGGGATCCCGTGATGACCTCATTANAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGA
+
)*#(++#)+#(+'$*$+)%(%*"%&("'"&('+!%!'"$+&#)!$))""+))!#"))%)$+'(%&%(")"%("*#($$"*!(!'++(("$+%#+!+*$*)#!#"!)(*+))+(#'#&!')%'((&%*)#)$$'
@r9107
ATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATG
+
<;$FA+7"%C'3<)%8,72H-:B2F&*(":>19=.A(;A"6A-0">$58:C,16>E$1>F0)=30.5"1*."#0?-(-07,7;B!B4-4.?.A:#=GF!;,1.?%C;>G7;
@r9108
CCGTCACCTCAATTNTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGANATTTTAAC
+
CHA;92=;9D-/@>$4&$8HB@6H95>@"<0*<8.C$EG%>4=3/=<D4AB,%D."?1#<4E
@r9109
AAGAGANNNCNNTNNNNTGNTNNCNNANNACTNNCNCTGANNANNGNGTNNNNA
+
#$#$$!##!"$$##!""#!####$"!###"""#$#!$"#$$$#!""!!#""#!$
@r9110
NAAGTTNGGATAAAAACGTCGATGACATTTGCCGTAGCGTAC
+
'#)+)''#!"+&+'#))"&$('$(')**(!%$%')"(#$"$'
@r9111
GCCGNNNANTNCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAAATCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGNTGTGCTTNCTGATATGCGAGGCTGGACANTCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTC
+
*$%&"###%%#+$(#$'%($'#"$+))+!"*"%((*#)+'$'&&&")#'$!&%$#&*)*"!+#$#*%'$%$$"(""!"+$%()#'+%"!(+#"'$##(&#(**"$%!()+!#!$#$%'%"(*'($'&)&+&!))$!""&%+"!*)+(")%+"(&(+'!(*'&+*+*!+*!)'%$+%"*+%$"$+!!!""'%#"%"!)*"))#%+&&++#+*!$#'%$#++!'')#*)#&)(#'!'+"+'$#+$'")&
@r9112
TACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAAC
+
>')&?;9D3%);H%"2*>0%A!(?D-"F;&",7<7,43!43<0%!
@r9113
TCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGNAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGNTTCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCG
+
D50"C9#?84"?=E9B:,<FC?F&8+*B#7>)A620(,@:D%B3H:,?!,70&A0'7!,G7;GG!C)A4A<C?5="HDA)3,7)%??249#$>7).>-@B86+0-B:?**7(F=,2%B61+C4#<-1
@r9114
TGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGNTTGGGTAAGGNTTGGGATTAGCATCGTCACAGCGCGATATGCTGCGCTTGCT
+
2E0:46,C%$3G&'<?08*9*"CF,#'=-8"B<)>4B0F,,;A;E%A'H3.G:B,0>)HC;GG68HB39:60.C=2#;8'=27*5D""23202:-GF;6*73=<6%G3<?B)4H5?,9;+@
@r9115
CTGGTTTNTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAAT
+
B3/:/7G,-A!,B")G#17):(1.&C;0:)*'-'6H5>3;B.<)0B=/CB*@>7:#3<(F:>A5-5-&+@6H:)8CH!@
@r9116
ATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCG
+
HE&9DE;?'%2()'02?6>4(9/C;H?>"C-:9"0)0A"HC!A-6>$?C"8D">)91:F*31($:&-#+,(F-&>"B8$B$41*3'4=:><>H=-%4!C992"9!
@r9117
AAGCGCTCAATAAACCTGTNTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGGATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGG
+
@=$),D8<A>3/(&'G=*5$;G#F0@+%%=7C5G,H>&D841#0H:<->HGB2;68?.7B6H7F7*0*5F7&%0?7<7=3A#!,&5(9F>@6.)+E25CC'@!'3!A,HHHD<589%,/>C=>E";B;:+:'2:#@>F$':/
@r9118
CAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAG
+
G?32H.)-@"-G>+GC81""HD(+F5):!,&#F.GD&$4+$=.+B);>)2#<6=6-!
@r9119
ATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTTTGCCGGTGTGGCAG
+
4F<3&+>G3*4@6(9+&#A8!8.+8='"*9E5=-*=D<&8/'1(#C<9'&"D'6$:#%-;)9("B?!B:18*/;=08"";=48=->%
@r9120
ATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACC
+
A72!4.*13&>CC(35<+*8@4)F5%3,$>3/B-*;F3393A@)#D'D%+22&>;GG$=E;.>=#
@r9121
ATCAGCATCTCCTGCGCGNTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGNTTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGCCATCAAACCCTTTCGTTGCGGCC
+
3;%7&8G#+*.?6>#.A%7?=!#G4>E*D,=+5&7/<>+41&1//)4.+E+1?738/=%">.>05(D$.E18&"<>62;BC,!2A30C!06*4;3-G$6*.G5'CA-)-?+56/+3.>@;5;G+&<1#;@8H@@99?/<H?,.H$-?/8-7-C'<+
@r9122
CGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCNTTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGGAAGANATGAAGATGCCAAAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATNCTTGCGTTTGCAATGGCGTACCTT
+
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
@r9123
TCGTGATGTCTGCATGGAGACAAGACANCGGATCTGCACAACATTGATAA
+
:190D1@@#7'9)E7?->(;%9$&6A@@%D@(+05G63;-.83F6D/GC!
@r9124
CGGCTGACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTCCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAAT
+
5?6>))1H7DB?!CB9)(%</&8)G>7&(..D@H)7DF-*AEC&.(?,&D391E4$%1"?:6*5(&$:/<7CE/36=:.0DG#(<A)'B%?99;G,HDE/,
@r9125
GNNTGNGTNGTGNCGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACG
+
(#%")$$#*$(&!"*((+%$#(!%("()*#+$&!(%&!*%&("+'#$)&!+(&'!#'$*('$++*)*$"!"+"!&"!&$$+!##&!*&&$'(
@r9126
TGNCGNACNGGAACGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTANAGTGCTGCTTGCCGTTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATAACCTGTCGGATNACCGGATAGGACCCGTAAAGTGATAATGAT
+
&%&(("''"(+(&)&!###''#""$++'))'+**)%&++*)(#&"'#")))*(###%&'$*+')'')"'%)#%'(#&##+'&"*#$+%(&#++(!&)*(%"!)$#+!%*!#'&"&&$$"&&$!+*(!)&#'!()#)!"$*'+$""""#+)"*+(%"!&%$$*++'*+"%$!%'"##("%"*'++)"""$#*&((*)&+'()&"$&*!#&''%'(+
@r9127
GGGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGA
+
&).?F%61@7B)"50=='D<GADC)+9H**B&'@:-*D3:+C>80E8F
@r9128
CGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGCATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGNTAAAA
+
D()+7"5*>H@E2+&-<5,=1/D3G,$E;(((H.*&730'977F1!C5G?B$2$&2B>9'/2(G"CA3EF$-.$-<)AE:2(*81>"4/-<B%0@+11@+$@6&!,HE#/8/+C"+5+795D?H1.@EED#4!3;,B.A+C>G%!!(?0$0>+=%(-F!*1(;''D%<#<4HDH6B5A1('0)H+970"4?>*7)()=8E=9%FGF++&=HF33%+:)'C+-!"(80,%%@-%1&;<,:&.?"$#B/$6F'==@F5/:DE>(D4.,$3BG#@'?,94/.B,+E3(FBE6G5$%F250H#<=>'87$.+#%#"%7F.C13E3,/'%%%1-#,HHH9G>53)%(;).&'7*!F1:#9=8,87
@r9129
CGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCNNCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGC
+
1C-C99/*%C#.E?$#2EF*;>#=:4+&3=9&=@1>,()D85$:=#",A(7/H&-5;#.B+,!7$G*-<$9%/&<@@.91A*5F?)BD%+!+8G7)'4
@r9130
GTTCTTGCGGTTTGGAGGAATTGATTCAAATTCAAGCGAAATAATTCAG
+
84*0@+!(E8?66-?,$?>#51C$3%C/6A!2;#%+=$8DBCD0@7FGA
@r9131
GCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGACCAGGTGGGTTGGGTAAGGTTTGGGATTAGCATCGTCACAGCGCGATATGCTG
+
<,?C)0"$==.!#.5?H>'.$7F%?&,$"C97D-CA56<"9:;1A+E6*9'7+'/>&:=,!.@EH/0,9/?;%34H)7=-.BB=-'B:=944*/-"-=H"-)@?G8"(,,2G,#.@+G3&%G2-.,=7"!'":F+"";"/.'E*E/-*.GCG)27837;#/
@r9132
NCGGCGGCGGGGAGTGCGGCAACGGCATCCACGAAGGCGACTG
+
'FH";..@/'(F<212=?B*6GE&9H52&E'EE8(#'-.><5$
@r9133
CTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGGTATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAAACAAAACTCAACGAGCAGCGTGAGTATTACNNAGGTGTTATCTCGGATGGGAGTAA
+
+&!"*"!*)$**!%+!)#$#&!#'$(#*((*&!%#+$"")(+#%$#$$+("!&+)'(#)+'*'!!""%)!((&#)*$)#%#($*%%)+)###((+$$!!&+$((&!"%(("!%'$"!("+(#(#''#"&'$'*%#(#%"$!####&#)"(!*(#(+&')#+)%*!+*#$##$*)!#)++$!#!)))!#+**$%)(%+''**'+'+$*$%%(!&$+!'%(#&$#++
@r9134
GCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGC
+
CC;/.9"%FAG52!D*H;09H*HFB9=$!;62:$D5F59-B>)BG',4D<#0DA=*D:52":$HE?E=.C/@8G>,<*H*),0&D4D=F=G,15:=0'?8
@r9135
CNCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGG
+
)%**&+*"$%##!!#$"&##+))((&($+'*#!#"#$#!+(+(!*!"!)*'!!+"$#$$)"!'"%#$(#
@r9136
AGCTAAATTTCATTNGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGNTGGCTGCTATG
+
=3$&#A+<3=%:/7;C7<.FEG>&;$0#'!E%32+>>&:-1:;B9?'72!52"3EH5#)!$,9-34(-47F@C'1%()+G;".:'>4B&>.!9.+3+
@r9137
AGGGCGGAAAAAATCGTCNGGGNCATTGTAAAGGCGGCGAGC
+
'5'-+,H+46@-#7AF61GHEC6E'7(A7D09)=./8$!'@"
@r9138
GGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTA
+
C>1(<**@<E&76**?+,86G($74,<B$:26%-",!,=95&:E5+0E/&7-6B4-/H9BCC)/4/"+.!6*&(G")7%D7"A:E3H)H%H<-./&B?HB4
@r9139
GGATTGGCGGCAACCAGAAACTGGCTNAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATT
+
(A);$&,"5#0/!0>4%F*<?>B#2$&"4<'3AB#";#9H=!8*CFD.B9%4=?/);"?&#,,*>A6%B!?B1',"*B,&<91-&&/4/C289G'.73#77%)%+
@r9140
ATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGNAACGGGCAGACG
+
F+54$H"A)!>C2(F>A?'H7>%/5"1B)1@B#H(#3+0B/(7/1<C,#5A-!<&@E6?A=H>;#0/"C/B%.:DDG?."!,#57",;0$=39-6:53H=$(=0&F9+=/)-#7*9$)<#)$(:%$-!8H)H@:&6.<<&&=G79!<E>'DG/*?!@31
@r9141
GTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGT
+
*7//*@1D&8GFG(&#G6%B0%F"E1:<4#*;!&/-*:EC&C4531?>3@03)>E:?2+AH,G
@r9142
GGCNANANCTTGCTAAAGCAGGAGTTTTCCGATGNGTTACAAATATCCATGAACATAAAAGATA
+
$&%*(&*!+'*!%'**#*&%*##)'$*!'*$#(+)$$+&""")+*&&+))%")&)'"'+(("!)
@r9143
CGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGC
+
B(H(AA9";E96;A6%4E@9;<'69,3&,64":C-*FDB/
@r9144
TCTGGAATTGGGCNGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAANCCC
+
+&&(&##)&)#***&()"+)*)"'**(((+&!#+!)*!&!*&!#+*+()'(&$+%("!$)%)+'%!)#+('&()*+!#'
@r9145
CTCCTTTGATGCGAATGCCAGCGTCAGACATCTTATGCACATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTGGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCT
+
FG?$3H.=<DHA6$/G-61+35!770)$76+"A4)B<01<>&/'#7"*#H*0D?,D43:E@(H0<2F7:?=6C7/CB&E,+>#9)/4D$4<4E!E6<.C@B=&*49A3";+&&8BB/;0'EG+19(82@2G8E)6'5:!-@)D:)5>=G:86DE,>)*7&11;"B-E"='4/#*;#*--F?,:!*812>!BH#/2:G8,B=FG,;7/C.A0;%+->*1>!GBF%6.4=9G'B5.7@B<;"#%'1(>81D.2>;*#99$G!<G,E5-6E"H).HDG%79/--.>(H8#G$6E1>7%C(H'D$+CG#!+<3<?,E+D3B;++)*E/H0A?*;#?D&#2:(/>)-;62'#05$*;;>6CB06A+3C6'=0B(F/;3%45@/5A,/:;C@,&7&8?$."2G*(#84
@r9146
AANCGANTTGATGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCAAACTGCT
+
%#"#%*"&$'%)+!$%!+('%!"+*($+)*"*%')'"!'!$&%)++((+$'!+%#&%"$)*($&*"(%!%"#!($+%!%$+!'"#"#!%)("!$(
@r9147
TTCATGGCTGAACTCCNGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAA
+
&21+5&A.F22+C*B6A?%G1.8/3?*EH/6;999=2A4?E@D-A1"G@,'>F.99+$;;AE>.5<G
@r9148
CTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGNGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAATCTGGTAAAGGACAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGNTGTCCTTTCGCGCCGCAGGCGTNGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTC
+
0,-@6"-.()<F2+H:&,)#!@@"%?$H?7)0C>*81:644')93>B40;G3A,$#;:C*E+1'274"<2=:(97>8,,#&G>?"7(!.0"A4)0$G:&@#:B#"D04@%>$@%<!=")':A%E2./"G)@=?1=$#+"3&::/:E"/9%8*=H)>3H-:.+)@*9/:@@7&+&72AA$?*!=474&D@=C@$0?#0/F&;;%B;'@1&B817?&/@''0%F:-@$D6E$*>%G*-&F@.!8*@+F<2+CF4E@!>!5=>6599E#87,4+:>/98?;,&(@%+CD6,4038*+@8+2
@r9149
TTCGCCGTCAAAGTGCGCCCCGTTATCCACGATGGCCTCTTTTTACGGCAAATGCTGCACGGCGGTGATGGCATACGTGCCGTCNTCGNTC
+
:6/:=#*<9<<A/)>%@:0,10A1"?@D(3/&;C*?<@)):!&<"-,!+2<@:5):83-DD3G600::1.B0*#0"1FF<E<%,#"87*84
@r9150
AGAGATCCTGTGTTGCCGCCAANTAAATTGCGGTTATTTTAATAAAATTAAGGG
+
=5::4.921#="!"866F$/.@4:&.>E:$43&?,?@(F8G79)6F%!#4'.)9
@r9151
GGTGAGAATCGCAGCAACTTGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACGGCAAGCAGCATTGAGAACTTGGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTANCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGAT
+
(&*'1G*.*0:FG?2H6G&(87$>29+06)4(?&%*(+(:)$A3G2.&(!F?'1'*"$+*A%3.E*AE+'FFH8$>"=-(C9+=@">(9F(C<F5+!.=C,<@4B+E',@:>7*01F;BDAC$=F:A).24+/38;?A'FF.6*)/,1C)%($$A(,&5:8,/$<B=7A*()&.5A4
@r9152
TTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTACAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAG
+
)///;!<A'/%"2.C3HHH,/"H3#?45(=).&@6+CB!(?H(0HG&%1H)(&1#A8"=7*D:*5'08"40,@:'3EB.D!6-DA)/2+.E?6G&2"F;5.91G#95%-$1D'162/!&.0><0@.=6;$154:(C/G;(&20D9>*DD,6='4(=34!D-,D36&GD%?!,+?08D:.B$9/4:0"GCC-9*<<0$E%5<A=2"=>H7E4<5HH&41E55&A+-+'E>C03#
@r9153
CAAAGTTCTCAATGCTGCGTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATTATGGTTACGCCA
+
.?;?4DD!<=.$03;)$3*@-3604F6=#,B>F$52G'D7#6B$0<=6<D@+A$.%5%,,B=A#,8))5.'G/63=*9(1+'H.8D'G6F;&F?H=:=$+,$*+88/%0'*D&)C:%8@&1(G1C?FHA034EG4@E#)@;FH2HH,!"4G0?;9D<.@C!G>$()5#HGG.<<>"D<50G6>FB'C.2*,1#!(4*5A(413&2#F*)C!;9?<B4/!,&+.$!90/#>5A=/;>=)@4C2:0+>&.:AH<A9*B,7E$8B-<H?60E=;;
@r9154
TCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATT
+
9,?1B(7:;,=#4F)2'7&C6./65BE5!=++2-(."9,EG?163#%'?5?H)072?
@r9155
TCCGAGCTGGAGACCGCGGTGAAAGNCCTGGGCAAAGCGGTGTCCTATAAGNGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGNAAAACGGCGTCAAAAAGAACTTCCTGCTACGGACAACACGATGGTGCTGGGGAACACTCAGGCACGC
+
+(*")"))&$!%!)!#%(*"$("))$%&+!++"*"+%)+#&)*#***(+(+$(+()")$%)!#$'%#(+(!)$"+!))!%*%!""+!#)(*%'()&(#&'!&"")$"&'!$((!+%$($)*''!($!+&%&'"+&&"#+#&#&%$$'&%('#*#*!+'"&)!!'"!#
@r9156
AAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTNTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATGTTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATANTT
+
4)?>);#+5=)%C!0;,F?14+HC-##8"!F!&(=C(+>E>H:$;3;@=4(310>F%0?A/;=<ED>.1#('/&<#&1,;)$(2-<#"E(7H8$:%&>?F3?366/:CD+:>-CEHHF"D$%A%3C.G.0;3#9B)ED/)FG*16.B-)C.&;=!EF/!6B9='1,4)8/3'1E#792)<!>9C5?+7BDD3:F>HE-F'*!5(7-8/>4&1@;&9C"@:B54C(B;H*+4A346C7>%#(!6G8!*7(;)571:H.5<8=<4G&491-)B/21D43<-.3EC#F=(.G1#&":1)G&?7',%=G:C4H./>H5G"<&0&#*,+,HEG&&@8=?2G$65E;3-+,6A6&B-93?E1.,63/;8.+3@(.-;6<=?;@7A'%(7)E$H.836G8F.7?77A=99/2=4#4>2.*B$E?<E?F+2!1=
@r9157
ATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGG
+
31$C/'/%44?3/%G-70CF'C$,-0(,HF2B3!2%7'=,-FB19)9-<
@r9158
AGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAAC
+
*4>D3<>F!3C)!;)>H5@;2B7"+</!9?D.49*?B*<4*DC??G6><$,8(3
@r9159
AAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGA
+
(*(.:=H7F3!%B4@'F;.+5C&!(1F<.24,:(A("*/':@==(;)?
@r9160
NCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATT
+
"H#??B?B0=F3!G5?C90.5%'0*/$*-<'#93G6,E+.D=7D9@#>#/8:-*G"*&H$.1)==&.#=+G+;6):-0>02.3)&CD&+)(%%5C)H:AB,E:0#:9#)9
@r9161
GTGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATT
+
!(6?:(<)*H7,+7+%975G/(>3,C?$4)G?28-,+0-906EB83D=:2E!:.83)7F6%?2*@:-A0);,1+0*%&)
@r9162
CTTCNNNCGNCNNTANCNAGCNTGNNNAGGNNTNTCNCNCAGANNNNNGGGNNTNATNNCCNNNTATTNCNGTNNANNCNCACACTNNNANCGTNCNNGNCNNAGCNANNCNTNTCNGANA
+
!$$#!#"!"!"$"$"#$$""$""$!##""$"##!$"#""#$"$"#!!"!$##!#!!$#$"!!#!$$!!$"$$#"!####!!!"$"#$""##"#"!$$#$#!$$#$$!#""#!$""#"#!"$
@r9163
TCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTC
+
4F8)=E-B).?DB";&7?4E)A<?/1*#1!40!A-547G4)%"=%<7>6G5+*%5@25C&>?4'7(;10%#*8%EEA=?H4";>3!E%50"48$)
@r9164
CGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTNG
+
F@C%$3F,"/#.;>($?!G)#6>H'=<0D+:B&8A77#F0
@r9165
ACTATCGCCATCGGCATTGCCTCTGCATCGTTCANTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCANCGCCGGGTTTTCTT
+
3B+!954:4@A@C-24%D.+E=FC7$>GF?6E(/9)12(1D(6?>>C6"529#G1=H?15FH':#<@021-@H)C10-'%4<1#F6!B!,<>"/"3#5@<1;.(7E;'&0&C%9/
@r9166
AAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTCTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAA
+
G9)*+2:2-E&=:?A5G?(+A!#=E<)C*&!0HC"(B4",?6:G/-*:6<%$:/$,9G5<H)&F3#HEA;9&><E>@8!;0:DG96F-!@H>0E
@r9167
GGCAANCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAA
+
3#7<1;!!8+-E6B!$@"<$<9?;/=59.A.:>CH:EGD(A;:?#!%D:?C5>*E%C!F8$7HD>&)<$:2
@r9168
TATCTTGTTCGTAACTGCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGNTTTTACGTCAGATTCTTTTGG
+
'%4/,<0*.;H;<5'+,E?2*F@*1463@@BG?BE3&'!F%=.E9D'7!AGG%5!++<')A40@2<=>'9H)A@/E'=!84>%*5#8H+-*9H('GH5&,AH0(90<16!B!9D39?/%F
@r9169
TTAATCTGCACACCGGCACNGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCNAGGTGGCCTGAACGAACAGTTCACCGTTAAATGCGTNCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTT
+
?;:!=ECBB<;15!;%H$,H$.G9?9!C(@#7/(#!;105<=?;&#-6-:AD6087E)3(?96:4)'H('-%,'%64$2"1>#BC!>,6HBH,*9@F&C>8'28)-D3#F-C;7<%/7@"=-68<16C&8;6!E4HE8D(7EB4B7;B:BB$!;&=;:88FCG!*?3C/1!+-E&H@?"*2>4&:9/)<C2G%?$9.
@r9170
CCGGACAACTCCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATC
+
;,.*)&:?H9E(A@7B+9-#)&F<2'/*/661$5E,-A<2C$3'"#49H8&#;D:;?1-;D.%?1:?D:@A2FDB>H@G=HC<5"&*HC=DG
@r9171
NACANGNTNTGGNANANTNNACCGGGNTGNNCCGATCNATNNTNNAANATNNNTNCTGGNNNGCNCCCNCNGNNTCGTCNNNNGTAAACCGNANTNNAACNNNNNNNNNAANTAGGNGNAGNTCGNNGNGNANGANNNGCNNNNNNATNNNGCTCANACNTTNGNNCTGGNNNGNNCTGCNANGCTNCNGAGTGNCNAANNCA
+
##!"!#"#!$$!!###!$#"$"!#$!$#!"!#!$!$$!$#"""#!""""$"$""!$$#$"""$!$!###$"$"!!"$!##!""!$!"#!#"$!!"!"#"$!!!#$!!#!""!"!"##"!#!##$"!"#!#!#$$!""$"#"!!!#!""!#!$!$!$""#$$#"##$$!$$##!#$####$!#!"!##$##!$#$!"!#!!!""
@r9172
CCNCTANNNCCNGTAAACGGAAAGTAAAGCGCAGACGGTCGNTGTTTGCAGACGTAATGGTGCGGGTGATCGG
+
"('#$(!%*%'"))%#%#)'()#&$+$+**(%)'$')"(%&*#+(&%"##%"%($!+(##)!$%(&%#&##)!
@r9173
NTNTANANANNNNCCCNNCNANNANNNANCCNTGAAGCNNGGTCNNACNGNGANNTNNATNNNGTCNTACNTNANTANGNN
+
!"##$"#"$#""!$""!!$#"$!"!"!$#!"$!!$"""!####"####"!"#$!!#!###!#"$!$#$#$#"$#""!"$!"
@r9174
AGAACATCCCTGCCTGANCATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATG
+
/C980#!9:"GACF$.++54&F;%.;182=EG<9(.H8A:,1-1.""$6C@='A.78H*&&.,9#"0<5#B,A2%*>6'206<0)<*:F"8:;"#1,A.;2:$;10!"#!,A;F3'@$)C-)-67B"/(A'.F7"45:;578+?=!G3$.;*&1EH
@r9175
CCTCGCTGGCGGTGGCGANCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGC
+
H6577B)&5F;25B"1!6-?-6F&)AF(>$@!D)(G*D+=E/--9*)=:A3#,6(5(;!DF',E2/?3$''#$G379;3%>%<!A:("0C&:H(E
@r9176
GATATTGGTCGTCCTGATACCGCGCAGGAGNTGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACNATGAAGCGCGGGCGCGTTACTGGGATGATCGTGAAAAGNCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAA
+
*&F32*A#A$&BD>3<%#35A8C-1<,-(2!0/&,@3(G.:8:2-2(A0%C,(C()AC85BH3%.176G9+',)G=(+6B"G),*#4,28"!A>31(!!9,);/$G85="4@;D-*4(8F-/-0$61?1!H9@A@-#+54>CG46H*3"01B*3?,!C.&=3;/>3(B?=GG;A&:(@1)19/!H.2..H4BH*.=7&=$=,$79G9?A
@r9177
GAAGGNAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTA
+
+'+)%#$+**+%"%)+(+(++$*''((+)+)(+)#%"$&(!#$)&+"+))!!&#&$)'!&!%()*)'+
@r9178
GCATCCGGATATTAAACGGCCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAATGGTGATGTCTTTTTCCGTCACCCAGTCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTT
+
&A$@2:%>B,#F/'F2C(5#4<.5832&"'8%8.)2''1;!G5><&3&<>53@%/)=%,)C1CDE59"(<=+5A#HG>3,2(%#%<*:'=?;9C$HFEE@,2*15-9=*2;D;8D/-&!G=*(:?2"=C<B)7.+8<HAG%34'@(/,9!21'F%C@H.290=:H!/"C2.C?#!FA:B**%<-92@"82E%48)-<'$,7>D".A:1(HBD(@C'=B:0;6#-)4"CA2H26(FF2=+C>E6C50"&+#9;2269#FE%C.(6%6+'"6@6>EB:<HH>?(6--@&07=+7CB'H96E!/F3:>78<BC5?5.4&'F,D+%5$FH!
@r9179
CGCATGNTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATNAGACTCCGCATCCGGATACAGGCCTCGCTTCCGGCAATACTCGTAAACCATAT
+
F(:+B-=?82**:DH371$441;16DE31+-80+=*#E"><4:9@A$09B/>%B?4-(@18(=<?#.'FD*?1"-BC+<=.(94.A%1&AG@G;>4+G!),?7((53;(%!0
@r9180
TCGCATTCACACTGCCACTGATATNCGCATTTCCAGCGGNCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTC
+
H/%(?'BH78B++F-(0?(!DEG>75E'H98:B-HH91.&/&&E*,2;%D>&896<*5;B3&D-93%H*4'@2E"/$>0>.5:/=:!A)&:GH"*:!%!*4)6C81C.%'F83!CE@@4!"=@C!)"
@r9181
TTTCCTCACCGATCTTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATNAGTCCGGACTAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCACAGCNGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGG
+
53#"G.>""83>@$@>=3-H.@B6@H0<F:1A.*G*D!5;(@@0*A?-;.%?B$&/AA$D:35&<$7"%:53E)@()!F/C1'7H84'!@+$8C;B68$'E"-***0+G=:0<:E>2D)+7)EE+-F;+E<"2FDC=:"+'G.3*'DH087(?F@$08$,5>/?&.;+%E-<6>>B+('!@>>.:3C**4E:4&;6/.B"/,'27#$&1(%-/!65:7>16
@r9182
GTNCANACTGAAAGGAGCAAGTGGATGACGGGCAAAGAGGCAATTATTCATTACC
+
$$%*""+"#'&&)+)"$"#*+$+&+)%*$+*+&!(#$++!+#$&*(#$$)#&&+%
@r9183
CATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTT
+
'D0/()#7G/A0(5%E(F/77!9++>G0(2++5#9$&(?$HH%<;GB>10"(
@r9184
CGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCTGGGTCACTGTTGCCCTGCG
+
AF#D/G5((D?D>8'6*#,-H##&?@D6H;F83/F0CF;!;&:B58">5D+*!9$A.&&%C/6?,58G@=8,/'1:E(&B<B#-8-0"&BF6?EB?6B0F/B0A#38/-%"6/#;(;#"F>!<15F&."E,E
@r9185
TNANCNNNGAAAGCCCTGCCAGCGCCGTCAGGGTCGCNTTCTTCGGTTGTTTACCCGCTAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCNGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGT
+
$"%$%")%&'+*!(%&"!%)++"&"#$++(')!#'*#%#*+"#*(**'($!)*$(#'&))%#%$($*))"*&(&)%#+")%)$+#"#"*"*$#+&$('*$*#$"(()(!(+!+("***''%*(&)%)&*$&"&+!%**'*++&$%#'*#!#+)*!#!))++"('*!'*$$"'!(&)#))+('!&#'$"%'()+%"!%$"#!&'
@r9186
AGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCA
+
2>&(C2@B8?BC+9"5.4$'H)1(,E$'0/8$=1.!$%H??41)592&D@=/:=D3E34#2()G>G07&D*.+D7@B$2
@r9187
CGTAATTCCGGGAAAGCTGCTCANACGAGACACCCAGCCCGGCAGCGATAT
+
&<0&!E!*>A6254>>1F$A8=3?2#/@?)8;H.0<B(5%;=,!**G2-DA
@r9188
NGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATT
+
';HFG$"8-))1!9AAF7G!-9'$60;F6!38C-D2>:@+B2
@r9189
TGCTTGTTACGGTTGTACCTCGAGTGCGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCNCGTTACCGGACCANAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATNTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAAT
+
+#07(G=7@.F@(>9B(EG0D8&CE'%93!3B:5(4G7=D?1E82E.D!4%5.D'2C&0%$7/25FE:$F8"-.B$=BF3G89<@)$3"$88;8B*=1B:!?A2-.@93'.9C4H5A($:A?330,3$G7B6*B:30)1>9H.B9G7=+G9C4'-?,#3EEB)#=487>9)92>(&B3;
@r9190
GCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCCGCGGCTAAAATGGCACGGGCAGGTCTTNTGGTTATCGAAGGTAAGGTCTGGCGAAC
+
;81E(2AHA;D;@:@.C%!(6&(<E:6C4(?#6!%,*C(+6,0-$;(:+!,(D42&FA50D<!?60C19;6H8D(-;14&)4B<?-(*&:$<+
@r9191
TGCACCATTCAGCTGAAAGCCAGAGGTAACAGCACCACGGTGGTGGTGAAC
+
D%?':$C76*6<3?;F9.E.(F>144G75;#E>;#3=+0/0%(+,@*)(7D
@r9192
GGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTGCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTATTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCTGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCT
+
+#$"!("#!#*#*!$&$!%)"'!!"'++&''!$+#*&$$++&*%"+'&$(*&)")!&++$$($#!($!!!)&"$+#)$'%"')$$!!#"'""!"%!')!!+'!"+$)&'#&%*&*&''#$+($#%)&"$&+%%&!'(#(#$+($%#!$)%+&&*!)!"!'*#$%#"$*(($!!"!*$##$%%(&&((&#)$')!*'#'*')+%+&&%+("'('$")!()(!(*"#%++&(*&$%##!"*#!")+#)#*")('(*+%*!$&)+'$*###*!(#"""+)"+%$*&"#$%!#!$+((!$(+'&*$+($*!'$*&#!+#&"(%)'*$&#*)+&)$#+%(!'%"(%&)(&+'(#)$
@r9193
GANGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGC
+
2:A*@9>872;-<D$E&:&!H0%8!+>'*G2#0#,6(.GCA+)AG0G+;6H/.8
@r9194
NCTACCAGGGAAGAACGGGAAGGAAAGNTGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAATAAAGA
+
+249F=;>@5#,4>62;645GA"(3E.)*.8>&+(>HA+F3'8!)E'>@.!F,3.$EAA0G*(,7/>.%.)>'!=C-FB67;+G%&,2):"0(;:--2+1G,(:FA1-;@F
@r9195
TGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGAAGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGA
+
#24G!-?86F;)42:%2$F#12<B-B."*1.4@D9('?/6)F&3&%E.7(A4%7">).>;0*A6#;H5<*(C#!*&/B005E6+@>>*!F!9DC$G.!BB&&<E-F813)2"4@1&-9"%-G7F,.!%33H5C5/.-@A7(
@r9196
GNATAGGNCCACNTGTNGTGATNNAGGTTGGNNANCNNNCAGTAGTGC
+
'%)$%'$%($%'*&''$"#&''$&**(&(&*(#'&&##")$&&+%$+*
@r9197
CGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCAT
+
=2,2&7H2*#A3>76E?%9=>)F6223A8>CF,4$$.15;H'A'6B;!2#>=E!B8
@r9198
NGANTGNCANGGATNGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAANAGAGNCGGCGCTTACTACNGATTCCGNCTTGTTGG
+
"$(%$'&$(+*!$'&))%)()&)$$%!+*")&$)"($"&&$+!")*!"'*%++%!%$!#!!"!'!*#%)*%'*+##+)%%$*')+!'+"$%"#*")$''""$%%""*)'''++)$&*$)!!(*%""%&((")&#!#'"$#((#))$!
@r9199
CGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGAGATAANACCTTCGTAATACTCACGCNGNTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCC
+
)9B<=C@C>(1A;'<.7+1+F65*3AA96%<#7%-1,.B>5766D&:2719*?ED1GE$-2:0C-:?4H*6'>B.7177)%&5+*748*?!B&<A:.D44!+D@)$'FE79GF)*A).C89E87030=8B9;BF6,C7@)!/H-.9A;+(A=*/-8A6/+F512@.#1?*A4!%*'+E)G&B)''27?5"#C>(=2BF$%A;B(%%+8+(<5>HH%0
@r9200
CTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGNACATCAACGACTGCTACGACCACTGGATGATATGGG
+
">=B-2A0,5,8-H27.A***GC'B?B#'#B<3:#4DA(5G*@%;A9H.(<EB6;0/E#/:#:"G56G6,?'./'D6H;9F,B1A!#/G#<B46*.9,'A+,?(8ADD:9"/=C$@3D!GF(D"7A%;%%(<
@r9201
ATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGT
+
@GF):.$4H25B+9212D;;;>A:'+<)A<908"@3A-&98<7G0"0)=9H;39/-A5$'H?>0$#$B8@!
@r9202
GCAATCAGTTCATCTTTCGTCATGGANTCCTCCACAGAGAAACAATGNCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTGACCNAGTTTTTCGGGTAACGGGCAG
+
?F#C))73@FBGE=@6@*B,*;,/A9%-E02&2C9.F1454%<4*='2,$7&E4;:88>:DD8=1GE%;>8#C9!D'01+4/0D:3#@27,E#"=5C,,(@)0H'-$B+F6A88'*"#'C50B=83G)E%B)+.,,@?(92,/7>#%4G1>,-"$B>5-3??EC,5;'893"::E98*/%-GB,3*%##
@r9203
AGTTNATNTTCTGTTNAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAAT
+
()"#%*&!+'"'&!'!*"%)$!!(#$$%%(%*%$)!(*+'#!!"!%#+)&%)%
@r9204
TTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTNTAGGCTCAAGAGGGTGTGTNNTGTCGTAGGTAAATAACTGACCTGTCGAGCTTA
+
&H(=2E*@>H'<2E+:.)C$E,'./#)C:)"0B-92/:;'9A(B=&+8"A<6>6%08".+0H?%)3E9$136&/)>C*?(@9"A52(.=>>"?-9
@r9205
AGTGGACCCCACTCGAGGTACAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGG
+
6!#&B.4F?&4*,=C%-&,&FDB6+%&C3&E)3-=G9.>AB%(-*(0/%9G?2@&7"<AF6;</'?B6=>'-D2+5H'?$EC(#AC6#9->)@#(5<A:
@r9206
CAGGATNTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGNATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGT
+
")#':+A=D;"03!'+."?)-(07/4,(4-%$=E3$!=?-.&$:=@@B1#7",!D?26#1$F!$4-GB8D&%?G'!)72C7H0"%0
@r9207
GGTTCAGGNCTAATCAGTNGTCCGAGAATAACGAGTGGATCC
+
))*%*("'&*"#'((%!+*)+%)("#")'+&%)$%(+"!)#$
@r9208
TTCCGGCAATCAGGCGGGACTNACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCA
+
+'(*)%*&$('$%$)%'!'&('$#*!#"+!++*"!'(#%)!+$'#&'%*(&$*"$)"+(%
@r9209
CGTANNNGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCAACAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTGAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTC
+
'*%*'!%+!%(!!#+($'%$""'#$%$'#$%*)''(&"))#+#!*'%*!'&%(!$)#*$$+#%)!'*++)"**''+$*$()#+%!'#%"!%*###$+**&#(%&+'+%))$&#&+!+!)!$$*)()%(#)&&$+)'+*'&'"$%#$*!)!(('++*'''*)'$!#'%('($"*+$&%$$+)(#'"&(+)($)+%)
@r9210
ACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGC
+
1ABH4C%02=C/DH-A).F?94//#>4:)G2@A-?'-*'5<1)GFF5*!8G98F!5*?.*3B5%+*"6
@r9211
TCTTCAGGCTTCTGAAGAGGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTG
+
F0'=#1DB&<!7'%7(2/3:@'5=861+*09B=HG41?7;'==C7%/H279$C9H5@0#,H-)F63-?C>E69<':C,@<56&!39+*G"@>CF7@42"3&GGCH,.A/?*-9?982<;:-?F<;;:D&19,4>G861!!5E8CG$;,!%
@r9212
CAAAACAATTCCCATACATTAGTGAGTTGATNGAGCTTGGTGTGTTGAACAAAACTTTTCCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACT
+
51H73@C7-2>7>5$B'?%HE>HC1(1)@/9C$).-E?5-C>$,##%5)E$A*B?%$B!'.(/"D/>H71:>+!E/)='>@%<G@!CD,G/1<H6&21;H:?=89;HH
@r9213
CGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGA
+
H($3$.3-+,D,#8C%@HF80*9-:/H,DEDAE(A"!<#>E:&!3G+D*H8)1?$7F-%=;1<@B&A5H(HAB%*#=:1930
@r9214
NCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGNCGCGTAACGCGTCCGTGG
+
&.#B%6E&.&2=:1E)>)C#-A-D/@&9<6!E9>2>*+&F<3>=!+<1!.D0.F2E&*1<-;
@r9215
TGNATNCCGCAGAAATGGANATGGATACCCCGTGAGTTACCCG
+
&$$')'+*&(#()"*)"%)++)+#!&"##)!((+)#)'%"&%$
@r9216
NTCTTNCNCGTAACNNNNTCNCNNANNAAGNAGNTANNNNNCNNACTNCNNTNGCNTNNGGNAGG
+
$#$##$"#$!!#"!!"!"##!#!!!!"!$""!##"$$#"$!"$!$#""##$!"!""#$##$#$#$
@r9217
TAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTNGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCANTGTGAGGGCGATTTTTTATCTGTNAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAGAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTC
+
&=C7*'><15<1+#6C'$&5A1+-B'1G%6(5@(A+";G">2325.6"/D463+5+8'"00:H>+.-;',&F286F4*/5-+7A4D91<"#+H=:"6>!@#>7.2D>H"D(3!&2:&1A-BF(8>6+976(6$%1=A2$E-6#0<7E!2.1-/H2&'>"B!6>)"')<,D+%*$'./*!EH11+9*H;B*-3G?2+2'.;9/'/@/"D+1+@:6B>#5BF:8&"D0#"77?+>G8'/*/6)=C9*-*.DC<"2@3ADFFB))FG==36?3CDH(7'.DC*-B4-
@r9218
AGCGTATTAGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTG
+
*#+%&#%%)(!&)%*!(*!$%%!&!&%!)#!+"+%%(!##&!&+!*)')$+)(*$&*'()&!'+")*%+"%"'%&(*($&#))%
@r9219
ATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGC
+
$CD1A=9<=3D>*#<9#=)8=>'?.6='=E932*17)9*:#)G7/9@4-E&<$=)F%?'+/4?
@r9220
CGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCANCCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCC
+
>4>B<C($1E#G&EE4C50*--<C/5D);=5<EF+D-@2G>@DC0*;'>(*53=9@&:@=99E#)=>;2C=,!!0=G%#29,A
@r9221
ATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGT
+
F)C$5*E0<($+H/7+<@)%CA-;3=?&$BE.BF-%>39>'BA"#?$.H95!@;+BFC20@(,''F(!?:H028@/;F<*&BH!;4C.+*"@5'C14>$+6(.H06%=6529")G":,347>$H#"D1?'688*%(F#
@r9222
CGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGNGCGGTTTTACCGCNTACCANTAACGCTTCACTCTAGGCGNTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGNAGGGNGGCCTGTTGCTGGGTGCCCTTCCGAATCTTTACTTG
+
?%+&6**7=+.@.F96"623<F=6??=&-5)52=C7='3,>08/!6&9;B,E(F#"C9F#(GC-5@+;=")787?>5H3*4"#-$>&,/!82&,<2B/'471:A/80-E"9+$6#,D=-/&3?+(:(E(@</7G-@.,E+%9:E<7HA#0=@05C4)D"8DD,9H>&';CD@;7$;78;=8"
@r9223
GTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATNCGGCATGTACAG
+
"C%!CD:5+0"A4C,62,&*G10EC$"4@#A:5<.&12#B7A7*7:>!B+0?3&-6D">+*%E6.:D"$8,9F-5>.B'.">)>F&'F>E%96EB7+@9-&0;?0)1
@r9224
TCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGA
+
C+;7>-<GBC,D?B;4A6=1+.%-7/3>E0988'74":;%904&>>BEF-/$?)HHF7$%)E;<GD/%FHH'"7,@."(/G!;:77,3:
@r9225
TNCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGT
+
-FG0:9;(G/%$"1/6E:-==@:;#.C2<*A5%62F/$3@;87-4AF>5'>6&+4FF.,D&%>".-F@6@:3EE,(>4:;,C5FF929>7$-DA+0?GH.$+=$.(E$-!
@r9226
CCGGTGTCATGCTGCCACCTTCTGCTCTGNGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAACGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCTTGTTTTATCCTGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCA
+
(:D-%C*C..7;A@*G1@:=?-(2G2/!&5$7(DDC&F:296FH2!A"=.8,H:5;;'#5(D0@>>B;DE$.HG+AB*.&$+%BF190FD$,3#A!$*0:$E7@)B:#*/D5E$5!>-6-21C;?C,#;'1(=;/E>)!*6EH7:,6!%8%!81(1B(E1!02+/$F)5@C)@D/!D'#?*8(#=0A<1>D0D30A6-G(17>B0"$'DA&$6HH<=@>%G.'8,%*E,?>9,H/DEB&DA818$2()A>;+/':@/@'15G4B4H;';7%D@;F4&#'EAF-@
@r9227
TGCCCATNTTTCCGCATCACCTTTGGTAAAGGTTCTAAGCNCAGGTGAGAACATCCCTGNCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACG
+
,7>;3H"D+%6->E#!*21#.01)<,-F#41D;=*;%-</!:>EG?1G+G,*F1#85500=45.8FD8#FC)53D337?=>7/5+7/E99>&2>50E?/GA6$)(H,
@r9228
NAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGT
+
-*15D)('43@$#@27F5(1>$D!=4D<9,:%#A5G7@A'=7*:>@F98:#!%?.+&&514A3%,3)./0@8&?=?*!>1?@4:0:@#(%8:$@>GHD07:@'9)9;=3&A")-817>?0/1AG(BA7)C4;H#&5?#@#,C8%H<B.:0@G++
@r9229
AGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCA
+
5&;"HE3<9%>#<-A&$4"F>E;$-C4!0@?*#7D&153#H(FB5*>,83*;,"G"@FA3D>=E*GH.>-H,%G&=98"?0:3A>$,';/5@,-(?2''A3?.56=#420C
@r9230
CGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATNAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAA
+
G&$GGG)0&H7)'?1&ABB/(C(+'62?G2$<?FG/79@&/#H.71<,2:3H31AC?=:1@H59G6G#D!3C:$0)"*("*'>8<-C1@';>&<@F?56#+F%H.#=:4,(=4-1?C#-7E@E;?67?C0.HH+":#$0*@//>'<*(=5/)D>"#?47E95")#G;:3CD!=$6B(9.F22;D%2'=6,,$;&16&(#=8@80?37%:D'5&1)5$<"%,2&04%04>1?258H-D3:0<!:FB,7$H$H3,!&'17,2CC@,.0$F"&?/
@r9231
CGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAG
+
(7/?@/*@@A-,/EE$(,/=/3=?A%<4*(<@?,@1=8BC2&G?&!9<><8@?6"5;C'25>$,!1"E@:G?=?<*(&E#(=5BG=)!G9;
@r9232
CGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGGTGGCGTG
+
*+3:9&5-$H:7"C8D-""(-GE8<@D9%#9/11B42.:.A0>F@")-%5053-1F)?<"C60)D0<8""H/-662
@r9233
CACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCNCTGTTGAAAACAGCCACAAAGCCNGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGNATATATGCGTCA
+
6#.-0D7--'.@E>FEA*/CA):0E:F)$99H6>C>FA@759B<*B3B@>E0+3)G%+F7A27"+HD$-24;"3)F7%<6++2D'"?G.E6E)1>G@/+<7'7-C&B6!?""A&44"E88<(1@=+/&7:@:&<*5D,B6-<#F2;"/#(@,$6
@r9234
GACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACNTCCGGGTTAACGGCCCAGTTACATGAGGCTCTGCCTGATGGCG
+
1=9;%BC-+?29924<9$4AG/,>+13*",?0=#9-6;HD<..2$1BD!C=:#=84;F30@?D?%E)?$!H208=;2<.1@@=/6FB1
@r9235
NGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGACCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGC
+
"+&*)*!!*+'"(!%+'#(&$#%"%)+*$!+)$((!!&+!%%)%("*'"$"%(+#$+"*"+)"###!*&%#&!"$!%#(+%)#(&)!'*""%+)&)$"!+'"+%+"+$#*%(*!#+!(!!&"'#&(
@r9236
CAGGAATATGGTNCAGCAGCTCGCCGTCGCCGCAGTAAATT
+
&/H02164-=!!$'1?$D<?E'H?:>D+<2$?>.4?*77)=
@r9237
GTGTGCCACTCACTACGACCTGCATAACCANTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATNCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGANCGGAAG
+
2:#B)6C*81@0$5GD&(B3.!;CGBG/C=DF;3CC0D/F;'5;&A5<;A/1$#.7+7C0)D>H-B0@#=:G!"9?8##//(/>G?H)5?=&1>+*7C<<F?!/5'H95C#AH=?%?D,$H?HF-77%7!),F)@565;6&>70B=H?4F4258</A
@r9238
NAACGTGTAGAGNCGNCGAGCCTGGNTAGCCAGTGCTCTTT
+
!%$#**#%%!()""&"+"!'"$!)*!)!#(#&(*#*"(&$"
@r9239
CTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGA
+
(5;2C#;@(&A!#*H9$">+!1504"C$/)2>+*$A9)<D,
@r9240
TTGAGCAAAAAGGGTCCGTGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGAC
+
<G!,,+:-,=C277*%&;.@G!ECH1?/,0/F<7%H=E@G,E6=&0D?:"!H2D<-/C7/
@r9241
GTTTGTGCATCCATCTGGATTCTCTTGTCAGTTAGCTTTGGTGGTGTGTGGC
+
2),:.5*1)"D-$&>A*>4&&@H,G'D41(H!5F8,920D,'DD?D7;=@!@
@r9242
NTTTGAATGATTAGCAGTTATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCANTGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTA
+
#'%)=&=&!E+C'<7440@F//G/0?0>3/$984C$(&'%=!??FH&+?@G;!-$,;!&>!*$67%E#BG"/7G-%$3GBCF!4&#A(0&;H1C@+!B7@F,"$>(??(*7%.>)':3A8>"?"?B.#@48933)A
@r9243
NNTCGCATGGCGTGGGANGTGCNCAGCGATTNCTGCNCGGNGATCNGNTATATGCCNTTAAGGNNCNGGCAGACGCTGACGTTCG
+
&&#"&(*%%&*(*$%*(&)%'(!'&(*&(()!*)*((%'"#"%'*')!'"*%()&&($&%"%*#"%)+')))"++!!%'))&"''
@r9244
TGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGA
+
$42;;4$4147'1(ED$'?;5&@G4<*=A9/285G!9"@+1.%9:%8?"3(;#,45$$H,H;:F9(.AB+62$!/?0A@%%68'HH:%5D5;+,$20@.6$F-)H')
@r9245
GGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCAGTGGGACGNCCGTCGATGGCAGAAGATCG
+
57,7D:5CH>=,6.<&0=7D%F-A88--*.'917C'<7>?$1'&*2<)/0:7::>H>,GB0F(:='7G4562=#G459
@r9246
GGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCT
+
=*4>&E8>1D/464)''&%/5**>!#2%#D+6=1FH.+!G$(:@%?%29D,=6(2+#8?1"<=B43A0)->
@r9247
NNNNNGNAGNNANTNNTNNNGNCATNNNTNNNNNNNNGNANNNNCAANCGCTNCGNGTGANGTCAATNNTCANNTNNANNNNGANACCNNGCNCNGTNNTNNANNGATNCCANGNT
+
#!#"$$##""!$#!#!!!!##"#!###!""!""!$$!""!#"!###"$$"#!$"#!"#""!"$#"#!"!$$#"!$"$"#$"!$""$$!$#""#$""#!$$"""!!$$#"##"$$!"
@r9248
CAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCNTTCGCTGATGGCATCGATCACACNCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAA
+
C3387/,140;$)4H&0AA""&;!76H#-E'C<,F,BF@*,/),)95!4C)4>"72,-,1>0G?C("0A>#/:HF88*?DH,7'*A?"/A3A/5+:%'1(5/4@/6$2D*$+)D)BAF@8,9;H4.);D=$&+67G6,C97@>.>>-"C9-EC*.*?6:CC.#%)5G'"F%75+2H$?A*D?#-1%/.
@r9249
NTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTGCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTAT
+
(91!CC!.*1<)=#;GD8?@/(@,/%$&-BG40=:6/',7B=)F#?G&(?5%B--C9H#6@;9C%;"A%:'A<,<F/EA5$;>6F66=9@=0!"*+B&.B$-B/5,E475$&(G37,/=D?24*2*3C?*'4<C'
@r9250
NTGGGGCCGGGTGAGGAAAGATGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCNTGTGNATGAGGCCATCAATAAAACCTATACCCGCCNGAAT
+
%'&&*+"+"!+!))&'"+)"!'%!&#!)'+*)!'()'!"%%$!*#'&*+!#+'&!'#+#&*!!%'+%(%$"*"*!$%&+*%"#")%#+!#'"+*!('$&#"'+'&$%"*#*#+'!+'#$)
@r9251
TTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGC
+
5+G"?"03FD=')1E@2$>:D%=2A7C4B463"/E:&D=-C021AH+9)/A7)1>0D4<*79+F=1=04(H;8>=4254=>=7#8C6H>
@r9252
TTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGNTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGTCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCAC
+
@E+:@,*8-7B%:G+>302#::;->,278+,8=?'@BH=0&E('=%,(7'G@5(3@?%2#/!?%%=8@)=.8HD2D6F%CE'&C=)%#F8.(:'"=9(">92.6(?##<6B.>9*.E;=C+@!7<4@>*<5H*F6$?+*;**80"/5F;GE523@)+E7'+0@G?=C8+)B!&&/"?C#@$3@$9(%H,8D<+;E#2-85C+!F;!#?:"7
@r9253
CTGTTANTNCNGAGAGNNATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCNTTTGACATCACTGCTATCTTCTTACCGGTTATGCAGGTCGTAGNGGGTGGCACACAAAGCTTTGCACTGGATNNCGAAGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCANGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCTGTTTNTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACANGTCCCTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTACCACTCCCTGCCTCTGTCATCACGATACTGTGA
+
%)*)%&!"!%%')!*&"")*(+!&!$#!%))$&"")(!()%%$'!&"*"()%&'#!"%!#*)"""#'"$#"#&*"(#*%!+&%##&%$)&+*)()!#+"'!%+!*))#"%&$*&$+'&!#+&!'"(***$$*'))!*$**!'%#&%*"%"!($"##')("(*%*!!'$'(#'$#"$""+$#'%#&)$"#(!"##(#'!("(")+%&&+*+&%$*!"$*)++)!$"$(&)#+&**&''"!')#)($))%+)'("!"$)$(")!$!"+'%"(#(+$)(%*"($)()!$+#"&&()%')''+*'(+*%)#)+'#"%(+#$('&"$"##+"+#%()()')&%!*%(!'*&!"%)"$))"+)!$$&(("&!"(!($"#"!##&++)$!!$!))%!#(%++&$'*#+)("*%'$#!%+')'"*''($$+%##$%"'!'&*$&'(%&#!)')!+++'#%#(($&#+'%*%!'&%!$#$$'&%!$'"++)(%$!"##$+%++'*'#*%*+!!!&&$)%)(
@r9254
CAACTGGCGTAATCATGGCCCTTCGGGNCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTC
+
):0($;0"!G7<+FB:00/")/6=H*H44;1$:;@HEEFD&H3;G=GD/.4!!21<!+3A?:$!#@@%<%2)?.?D?,G:/
@r9255
AAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGC
+
12"?/4?F?<4E65B1,*9A1+>*5.?:<D*#0B(#A!E&E8,0BG,8:%%+F,1#"C#&837*DB/;,,3!(F&FB5#0>%&45B*,'A1./.FG#72?*-73D-9ED1H(5;F.HB
@r9256
ATTTCCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGT
+
8#H$H+/H5/8%<')?G-;(5!D(#8)0+=+"C!03F,H:C$:4
@r9257
NAACTCCGGGACGCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCGGAAAAAATCGTCGG
+
!&EGB%!2"'+-<9B$"B=?9":D"9"A1#9#-."G52-:>6)!='.-DBC.!<?B<EH''.*$),*)%7#(18=C#'F#4
@r9258
CTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGAGTGGAACCAAGATANCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGNAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAATCCCCGCAGTTA
+
"5A74DB,:;-;<03"0>@/:&!<<1%??11&2C/8C(08>@">$0-DD8<D=D75E*.'E5,-52>(B@A66G8+!AGFG!7'@E3DA352!7(AFC+!5+#G)+0$G(A$0F$68287>.:)#E&4):!?A%*!F7CE/8A=$CE/+)!$71E'D#4=:-EB.7;,"D0/3-A0/+
@r9259
CACTTATTCATTANTAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTT
+
B6"$->$571:-=5)B55F2D"(@5G'%76@->"12C%E,6H23,B3(:0
@r9260
TATGAGCCAGCGTGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGCGGTTATGTCGGTACACCNGGCAGCATGGCAGA
+
061(9/'>8..6"!=E>=*%8H3#0)$3@B8AC2=28B-*G.FB93="82+++?GH&C<'%4B#G('./;H@F3;119<$B&<50;/(+7=@1!D!'3+GD@,<,8)&CE!)@*#3"&G14-208&:G#,3'*16+:
@r9261
ATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGAGCTATTAGAGCTTATACAGNCATTCGGTACAGAGCGTGGNGTTAAGTGGTCAGACGAAGCGACACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCA
+
$50/".,'>B4@5<6DE<%6$-5!>>"G#6CD.1#49HE7..AF,1"0(F$:GD&$>=%$:(>;#)=@982*9=5<,?F87(6"H*C)(&E$0>F2B#GFB0%H4E")7*/!/6G9#;%!4FCF4F.9!75)!HE?-076H>?/:/2F2)>$!,<@;CHA2028F>>&*.4/%9;!/;101'*5!*H'8H05F><5C%4740H$$+4:0&<0:EF--#
@r9262
ACCCACTNCGCCCGATAAAAGCATGAATGTTCGNGCTGGGCATAGAATTNACCGTCACCTNAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATTTGACAATTCTGACAAACCATTTAACACACGT
+
?:,!H84??"/7/=@<4)E82#6%$;24E"E41B"A%?1="8#75AB;>6=@8.H$='.E.+7@<1??5.<)2+9E)@*7@#'4BDG&E:5??:$184@@/'!;,&#(B+,2;4>D+,#@)542G5"5%,A1+1F2:%*E;,$0H!G"$&66>%&
@r9263
CTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTATCTGCTGCTTTTTCCGCT
+
G,>:,AA/88#*4BF,>0<4C6&$.%=85(29.,>HH6$.(%!)H-(.+H8%$2@-:BE7/7.A09'45A*3,0E/E,D3$6,H.
@r9264
ANGNNCNTCANNCNATANACCANNTCTNNNNCNCNNNNCGNNNCGCNNNCNNNGGNTNAAAAANNGTANTNNNNNNNGNNNCNNNCNNNANNNNANCCNTNNGNTNNCNATNGANNGTC
+
#$!#!"$"$$!$$"!$#"$""$!"$"""!#"$$""#"!#$$!!#$"#$"$""$#"$#""!#$"$$#"#!"!!$"#""##"#$"!!$"$"!!#"""$$$#!""$!"#$$"###!#!#$#$
@r9265
TTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGC
+
6G?*+1272D#2"5;F!?+#"DBCF6HE+0F6/=;#EG,9-E9>,=F:&+B;
@r9266
TGATTTGTAAAACTGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATTGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCTCACACTGTCCGTCAGNTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGNGT
+
<2?9'68!.G1-58=9-E8?;&CG/<82323/$;F*"=?<+45.7D>.&359%=B$>@!75?&'9<<;:65))4!9<>40A&9==3EHGAGH)<9$(&!<50@)7#43921"$!=.)""#BC1F4'.-!H33.>F7,$H&28E-/D>$E6%3#%9'=A(+0E@<+HG)'&=D0".?/!3-#;A4,.$6-D,H<#&!$11#D+B:?B64&(%B$"$)FB'#>'1E+ED6(B&86A0E2+9A)79-%CEC@366&.,7'C<B%->%B!0$9<0%GH9G',F8;B>D>0*<H
@r9267
ANATNCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGNGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCNAGGGAAAGTGGCGTACAGTCATNGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAA
+
'(@!(F31HA&?&=6,=319$4<<@0*@$5>,'A(*@160?8!.6(-A(7!-D(BEBH&)5+?<2D4$(1'GA$B8,?#EC+BA@>)>C%HG72E;C@8@;D+=%,80@7A?4!9D*%(46())3"'A15/G!%G8C9B;EE4.%%6GF*21!@4(3E?F3;";/;2<@2<C,0#-@
@r9268
GGGTCATGGANTTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTG
+
15-8=112%?$/E1'.C":>.+:9C!1#!*H;"--.?*9=4FG94"=0A5.7:/"?6#57
@r9269
AATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCNGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGNAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGNTTCCTGAAAACTGAAGCNCGCTTTTGAAG
+
<D6!)+%>.9@5D$,=-A)C7ED<3'2!7:=>G$=8=AB#9)8+D;,>0'6)FBD9F'3(D9'.#4<.H.4%A(9$%&92$,@8;G$(8C#7A#@#!>7&7=;;3:=C2D#(.H>0C-=4>&&@><D;--.<E37"66(5$1?265((G*F*$*H=?<B5&%&!'6''+8G8F7H(/CD,9>4#:
@r9270
TGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAA
+
C2?B??*.%B4$C'EE/7<?@55"?=+-')-1"7DB)2/"#.1G"
@r9271
NNACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTNTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTNTGACGGTGTTTTCTGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAG
+
"%@:#(=92>.$:-!A?C+0-%+<A%1"D,.7'$<$&'7E5H%3?7F6E!"31.E/+3E=20@&'#9*830411H=+1%*"*!C1G"D#D!<7G69,&.C$/0E!G9-929D-0#H*8(65$:BE"4C<DA?%H@A28:4.--/'8;&=D2BA%7."::'%/F+=414E@<:"!#<198:-27D809A!,A(((;%<-F/*"9'27@$=H*8-E:BE*-@1(:+-8('3><4'C+H;AA;6%)3H:CGAB37;6(38C5$.,A$:5/6791?0G9-28=4<=%0@A=6H.)G,8.,D2$6,%9EB=9<,70.D/%G9)*?<#0!)$15,36%A3D6;,@,E'99'C1/)>$FADE#!%11!6)BH90)<5:6B79?8,")H@.AH(E-<A.1:+'!)8!
@r9272
ATATACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCANTCCATCCGCAATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACNTATGTTCTGACCGTACCGCGACTACATTTCAGTCTGCATGCTACTTCTGTCTGATTTCCGTATGNTTCAACGAGCATGTCTGGAATGGTTTTTACTGGGAACGTCATGCGGCCTCACT
+
%)%+++*')*)&'(&(!&#+$("&$+&&*&)'&##%##%("&*&%+%!&$$'*)#()'%+$+&%"%*!*!#)%$#)'!**#)$#+*##&*%(&'(+!&%!%#'+!%(+&$+$!*&'#*)&#+%!*+$&#"&"&#+!+!*)'$)'("&'*&%#($#$!!")$$'('!$$++"&'%*"#(+*&+*$+&#*$"&"!*(%))')$!'*'#(!)#++&(&**!)('#$#%*#)*(!#+$'%'#*)+%"'#&)(*
@r9273
GGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTT
+
$'$'*+!!'!*$$&")#(&(+#)$#*!)"&'$*!(#&*#("#%*!$)***)#$&&&(*(&&!)%#&"#$
@r9274
GAACGTTATTTTTTCTGTAATNAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCNGTATTCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGNCCCACGCTGACGGTTNCTAACCTGTACGGTATGGACACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGG
+
549",/"?>:533)@27?.1<$'>A281<8*H33!#45;4D@:H-@=:*=)31A-7@4AE5?5.19.$C=1A&?4/3:;A+@=H5(?90)%8,(?-%C.&%E.7CDD>,G*/30C;)B'EBCC!(C#</**F:;B$A$#-%<%"+3F.3=G'=?D?=F@;$!B8!((HD?7/;H<7<H&3&/>2:8;'!20B0%F'@F:%#6E<6H4<
@r9275
NAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTT
+
"&G%A*'B3#2@+A&)CG!H$0!,26G4@&G(6;8)'F(7"D=$'*$0<(H#12)
@r9276
CTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCANCGCTAACTTTGAGAATTGTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGC
+
&+*+#*!()"&$$$#%#"!*!)&'!)!"+##)&(+''"+#'#(##&(&!#&&!!"!##!&+)%%&"**&&!($!!*%!!*(')#*+!*!)#"*$!!#(&$+*))"(*%#'%!'+$)&#+%"('!+$")*#')*&+%(&
@r9277
ATNACGAANANNTNNTNCCTNNNNAATGNNCACNCNNNTTANAGCCNCGNGCTNGGNNNTTCNNNNTNNCNCANAGANGTNNCCCGNNGNNGNAGTGNN
+
!$$#!$$!!"!!!!$$##"#""!!#!!#!!##"!#$#!""""##$"!$"!###$!!!#!$"$"$#!$"!"#"#$#"#!!#####$$!""!!##$$$!!!
@r9278
CAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTC
+
H06@=#>ECEG&!B-A('=!=.'*>!68!/!59(G>-<530B'@>"/$005GF0=.3#"1:>*"C;3;6E#"#7!11%#F:37#;.%:4D?H@)C<G3?1EF1#F,%:4:H@,7;9
@r9279
GCTNGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGT
+
+&(#$%"#"'&$!""'#"&)%&$('&**+&!)#$#))&"'#"!)!$!!#+%&!)!**!%('%+
@r9280
TGAAGTACCGTTATGAGCTGNCGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCNCCGCGT
+
G$BA"(;5.6&(*)&>A">@)<9/;#<A?!*6)-G4+G%/4%*>G4G%/0/AF+,01&9&A-&
@r9281
TTAANTGCCAGCATTTCNANCTGGNTANTNTGNCNGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGT
+
"*&$%!(*$''))'&'&!%**'#"!'($*'(('"!%'&+!"$$&))'*#+#)%(!+!"")(!$'*+)*+!+$%&&')$"')$+)++#%%#+"$"!+')%+$*(!
@r9282
ATCCCNGCCCGACAACGACGGCAATGTTCCCGGTTTCACTT
+
89>&1DCAH/6$&?1>!5971?3-51;!D(D170-7$?92$
@r9283
TTCTGCTCTGACCTGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGNCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCGTTTTGCCCGTTGCTGCTGTGCGAAT
+
<9&:>GF?/2#.%HG832$:@G37A:#&29@)2((.=B)6'AC4&2!<:F7!B*.-%2'#'#B$6D:G?/>G5DC<D.-?4:D%.=G!-"'<@8H2410AD<>>"&+5@/3.$-0$D>'<3"572'45#',!")**)A$5G7+?#.?("5/6@*0'
@r9284
CCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGT
+
D8)8B717;"/7D"%)G1(*2">;46@H(436&!HG$@."%<D.8%08+98A!7*EG5
@r9285
GCGGCGGCGNGGNTNNTGCTGGTTACTGTTGCGCCTGTTAGCGNGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTT
+
$&&#&%"%!#%)$)#+%''**&*#!#'"*'"))!)*$$++)*)%$#)&+(!%%()!%')!*''&'&*+)(''&%'(%$+&&&)!'$'*)++)&%!(+%'$+*$#
@r9286
CTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACA
+
$4@3GA!C,:-$3H4FB6:D9??H74H,/2?2CD3A$&E;=@#04*+7>/=9;H
@r9287
GGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTCACCGTCGAACACTTNCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTNCCTGCTCAATCTGTTTAACGGCTTCAT
+
;?3AH<G5C%)G!(C-9"H9B>8(7$"?,;B%121>$1!$D,%A:0GDH+1-*7)>"D,(1?$==49D!4?65E:<D9=B7&9<1:57"(7?&-F6<>3H4$<-)=BF%-=A8DHHG<;/($@/&'D+#!3F6(!B/932'--74<F#(#*;.E%*3B(0-C<@B%D&46>"#FBE6'8075/<?=%8<,G&F"F8=/E/@,G;")+4G060??98).EHG!.=9GD:
@r9288
ACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGANCGGTGTATTACCGGNTTGCTACCAGGGAAGAACGGGAAGGAA
+
D;F%D&'*1<%#&AB*.+;@<?38(,)H>D3>714)7*9923AC!?H83BGCB<)7B$=/0>D1!*!6)?=&1.0.H+F4C@-
@r9289
CTCCGCTGGAANCGCGTGTGTNTTGCTNACAATAATTGCATGAGTTG
+
.0B1@.'"+)&.8>>690<<A&/B7;FE9:*8B+-)844FC-D$()?
@r9290
NNAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCNCAACGTGATAGCAAAACCCCGCTCCGNAAAGAAGTGGCCTGACATGAAAATGTCCTA
+
$&%+##""#*')&+())"$)+(*!"&)!%)&#()%$")!)""&#!"(&!#$)+$*%&)+#!*$""$!(#""*$%")))+)#*(!)$%#+)%%'(&&)
@r9291
AGTCGCGGCACGATGGAANTNAATTAATAGGCATCACCGAGAATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTATTTGTCT
+
1A%3-F/9G#GFG"<&3(@)2<.<@0./@:89()/F*/<C4$=FFHE9C"F0E6G%9::?$+FA:%/&F)F+,%?:H5@3FA>+/&"H?'
@r9292
TTAGCAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTCTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCAT
+
0B9%H>7=2G!-3-;%"/+.@542*(&-?4F"?'<?%$$G?CC42HEH7&%"*2'1D);C6"C:1CC<380'',D.9ACC8<A<5:G2G%!4-$./:@0*!9@F7*@>(;1>,CD!F0=")/3BD>&!&<&E<6C%+/",+1%<78H##.$?9B36#423'"-#70&DEDG94+G+)9
@r9293
CGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCGGGTCAGCGTGGAGGTTCAGTCCGTCANCGACGGCGTGAAGGTAAAAGTGAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGNCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGACAACGGGGCGCACTT
+
-"1$-D<+=$B;58'/)4(+3;;F7D)F'-<BG4+B/;@%B)5B1D1$H>D=$2(7$@=7EG,!,D0,3H5F;5AF4"3)9=.@>:8H=>)#;.F5*$0E-*D-?28"#597.&&+-.5,216(?4>;&.C?>415(7&.F(;.1;DH+>D6%'>F1:.-E2?%#&,/687#;"77'H?C(.DC09FC)@;C''(G''",%F7@809$.#69+6*:(B?289/C>H9&-D=0?3:+?C)7!#'BF055G(H57G)B+#-8B
@r9294
CAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGNTTGGGGTAAGCGCANAAC
+
F9C?F&*&%?D8=!8(-$1'7?&1'G+,D.1D/)#C4@0<&?EG7-(0A:?$249CE$A+#":A+".6$5($?AF**:)3+5;DD
@r9295
TAANGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATGGCCAGATAGTGGTGCTTCCGCTGACGTTTCGCGGAAGTAAGCGTACTGTCAGCGGCAGGACAAAGTATTCGATCTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGA
+
")"!(+%"!+*('$*!)&+!(%&+%*")*+%'%)+#((!$**")(&"&'($(*&(#!+$%+)&+)("!$*&(+'&)"$+"*$&')")+'%"'+%&(%%"%$#%!)!&%"("&'*)#"+!#+$!#&&*$&%%##(#$(!)')$!'&$$!'"((%+"%!%''!*)+)$"%$%
@r9296
NGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACT
+
#;4B".B4&C%;.4G*7H,3;23+8%/3/:6/!:<7&&A&%D##(@#A92C0-64"&D'2><%.AF0"G00$$$31&*$8@.DF80AH>'?<:.A5>H"$F#G4C1@6A@%<%&$EA>H>A6)69?
@r9297
TCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGG
+
-F@,-C+)HG9,*2%$F39>.1-/3.,$%5**H/2)A,-=!1?B6H,$##A:B7
@r9298
NGCAAGTNTCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACG
+
!=;2)%)DD*8&(,!$0>EA6,(7)6/=3-G/;!9)=.*&F@"BB:(:22*9$9#A:A*36'"2@=86.1=(&1H:>$05E;).B;G%-9GH10(>"-""0EH&#$8!-+6&475?;)$8E03"1H;6@$;#D"2@?B!8:$G,&$8*G*H29A+!7E3-=<;H+&.B;74%6H8#64H77*?8?8'B8>24H-'204D@*3?7@51G&"<&G
@r9299
ATCTGNATTGCTATGTTTAGTGAGTTGTATCTATTNATTTTTCAATAAATACAATNGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGGCGATAGTGGGTATCATGTAGC
+
A,B'>*8!1?,<5$C87?H57'071%6;?!*/@0$GH6<$;F!H+AFD;031B!F>C9.1E?!&'!)GDF(03?;9BD&)%#E4;B+.+C@5($G<1)/G/94*>!7.5"F>-#A%H/)$$>+1)+C.E6&7;)55+$GH2F9:8':%09*G&B=3E5D(=565B>D,B(:D&(8G#>9<G;@>!E2;'::@HE&36,-0+%BFG=D':5+4@94$
@r9300
AACTGCCGGATGAACCGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAA
+
%5(9;@6:1")*%;>,%5>E=,E'2($%#BG@B>&!222210=6)@+,/?-.!:'=(.-'0D*94<-116=::80-!$/A1<.90":A99!*&4:E?+:B9$(;:D83:'$8
@r9301
TCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAA
+
8.D&1?-&/$G,35>8.5(=F<<A<-''!56C4)!?#;:D3(G*?/EH&#51.62!A
@r9302
TCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGATAAGGATGGNAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAG
+
F(@83GAH@'9?.H<9"6")@5-F,@@9H!,7*1B-B3A$G>+<1('6BAG@#"C)CBD9%'7#;=+>-GAA6<G42#/=6)&<'%8(2A6."/>B;B9;D8>;1#F<+:1.<:C7B&<2.E#('-F40%=<!*F&51HG8/7&(1<)
@r9303
ACCAGCACACAGGGTATGGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGT
+
@D!CG9C-1@*G36.E.4=?0'.F%#<!FG&>4"5'D@2;4:6F3.?H$B*+9"B7/B&-,*)$1/#H@@$"="78E6"@
@r9304
CAAANNTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACCCTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAG
+
*)')"#*%+&+!""%)!(#*++!*'$&*"(!)*&")%!$%)%($$&%$+'(*!$)#)")*"!'$&"(&$++$'$&(&'"&)"!'')'"(!""!$!%'($%*$$%!*#(&&+!)!#('!+$()$!))%!)*%!'+)!&&
@r9305
AGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGCAAATTTTTGCCCAGCAGGTCCGTNAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGNTGCGACACTCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCT
+
E8/G=7&2AC699:,9##;D*2.9B1@(31?<(4!D0-=E9@@+".*<G?+>)E<)!+!D4!6/?&)61#39#9AG??<:0536*:&?E?%&!ECB>("-G)7B04,(DC4"=6B7D$E')6673D#0*@/*=A$;61)6A'G2><$628H$-8>&?%!.)'*+3,#C?#DHH)?(:#+4%630G6B0?EB6=*E1&;,@2.#?H'78@5B#@%GGB
@r9306
ATATGTGCANNNTTTTCTGGGTTGGTGATTNCACCAATCATTCCATTCA
+
'"#'!*%'#!!#(+$'%&"$%#(%'!(**)*)*!$$*++'+(%!''#!'
@r9307
TAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAANAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGANGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGAC
+
--1*1D*27@,E<"*%$)C(@E:G;=23&,$2'C*'7;G"84G&,8535>4%"CAD,684)1&%/6$F$&381D<:EAF0H46?A@+;=C!'&)$,E,%&<8&:3CG'1539'H)!&1+0!53>,@'?E"51;"2B#!!D**'D>7=C(5@5A#2%<:8"/-'5).69EF.2'-?2>"%-D?$C.6:@4#F=1,/'AG@)-8'3=DGFH?'?@7!(G%><><6@DB%$1(*14(=%,3(E@4#9%C>9:"*G650:112$7%9*"89!74@:762'E41/!A4=,9#A:5%.=(<3'%C'<-9>A9&H5>"3/.D=8$!9!*=3
@r9308
GGGGGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGNGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGNTGAAAAGGGCCACGGTCAAAAATCCGCAGGCAAGNNTCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTGCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGTAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCTTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGG
+
$''$(+(")("$$("#'%+)(*#*%*$#++"%+$)+$"&!+""($)$))&*(&%("*)&&+()"#'!%'+"""!'%%#!$%"%('#'!)*&"'*!!'&+'!*")+'%%!**!'))%%"#"##&!$%&+&$%'#"(("'$((&&%$)(%)&+"!("()+*&(()%)"'+&+#&((&*##*&&$"(+%"(!!(&("))!)))()($)"+(#"+&&*$)$!%!#%#*(&#$'%+(*!**&*$$#)!#)#'!$(+(($#%#"&+&))&*)&&#"&)!%*&(#'#'%%(##(%"(''!$#""'!%&"&)"''&*"'((#"+&&'%&"$!%)%('#''#)###!*'+!"'$"(+'(#+"$&((*(&$
@r9309
ATNCTATNTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATG
+
@=&H"9E%>,>A<(:B#D4"8)GH,E+/2/0$&=(18G*0)!"H''5-@.,5),>"(1!8?%&$2(
@r9310
CTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTAAG
+
"/:3D$42%E>:5&,A4?'"&>.0-1%,=GD=92'@8:H3,'@AF3H7$F27--@C)?%.5H*2EA/8*<@>><68,E#!"?(C7<D2:A4+B5B6*A7.C=0G744/D5C7'?B*:"5"5?6'CHB"@G6'8>F7<0"FA#ACC>BB7GBF$/-3F2C0!HD;"4A0&DE,;D@B-(8/CHE5?@E8C";<$BD6#/EC$!!'
@r9311
TANNAGTANNATNTGGGCTTNACTGCCGGGCGCTGTAGTTAT
+
()##''$*(&#*%+&$"'&$%*'!%()"&%$#$!$)'*'++"
@r9312
NNTNCCTGNATCAGGCTTTTTTTTGTTTCTTCCGCCTCNCGGATCCGGAACAGTTTTTCTGCTTCCGTAT
+
%$&+*%")+!+$%$*(%')"$#&&&'#(!'*(+)$!#%&+%*&"(&("*#"%+*&"*('*&*($&$#')%
@r9313
CCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCANGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCANCTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATCATNCAACCCCGCTCTTACACATTCCAGCCCTGAAAAAGGGCATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATNGTTCGTGCAAACAAACGCAACGAGGCTCAACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGTAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGACAAGTTGCTGCGATTCTCACCAATAACAAACGCCCGGCGGCAACCGAGCG
+
*)4?"1=A73??9E-,(F=9*:C8C)99%@51C%8,%448C)09>8>1,G@2#31D6/>-96D-1(F@G%?;,(&CB89/;+$5@+B0;B!74-;F(19+1G=GD!2;-=@D91285>(!3=,%6#>0!:;(2G767':<#0$&@"#9;?7#!!FF9%"118#<A*H,G@D*1&:E,9H%<!**9!H7%+8C$3@#AD?:5C>/5.E:.099"+"52C6=H2,<47D)8435B$-<F(5H'5=C=?07&'><1&*B:6<8+&4<9?2!?&>E8H?A/18#:*,!'!4E%F+C?*"=4C+9%7&.D+<@@$15@$)E510B+!9$6F5*6EF4?844#+?+"85G.'1"C'7$8#1A>,=AHC5&<4F?@)(?G@=+?E2BF)(#*H4/:#9'$%".*%8#3E94+4')-B</52$!D*8-)(GA:+%54C(G$A,F'25'G:6D%-$!7.%%"E*/2(,H+>,*$66.,FF::<+2B#(8F-(?3>9!/;#E&C6#($4$4A%--<!9,+G-5!4@G=-?84@%)'1A&;%F<BE$-;D*A#A&*.3(AE??('"4H8G00$D.;7246!A"6"
@r9314
GAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGATGCTCTCCAGAGNGTG
+
6&3.C'&G)A:(CH=-5C(1AB9=B:#$5$,18-2*3'C8DA(04(@H65:9%2+-0)%)<>>-09"$@&4A,74"*710998A2*,70#E-&C6,0"H?=?29%CEB=!EE=-&A#-"%.2#8'G.A2+A&E?'B93A1D*:!4#2)CCAA(404E&+?B#)(7E(0,(<;36'"8"7C0;E(%1EE(+/B$*17%A#;,,C4!$,C?.&(2E763<6D7
@r9315
TGTTAATGGAAAGGNAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTA
+
"?)BH3=%#,@+F55EE>>&G%D?&#%C;(!=4A3=::1#+924"4266A
@r9316
TGACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTGTGTNTAAATAAGGATCACACCATGCAATATGCCATTGCAGGGTGGCCNGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGC
+
)!"+#)++*"!+'+%!)$('&$+(*##!$(*%#*'+%$*(++!+")!*&!$'+'#'#&%"$"%*"#%(%+%$&&#)&#)(!)+)#*#+"(+)"'#()("&$+*$!#+%*+$+)#$''$!*'!$)(&"'&#))!&#+"+$&'""$++%'$$(!"&!*&(&)
@r9317
AGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACA
+
F%B)9(6'8D2HC@=745A@8.-E(4C0ED0407<(=EF4=%8,%@E?
@r9318
CCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTC
+
)BC2%D@9%<*;@0+,2%$%D2=@H##-*=$)81CD/F*<)@H584F*<%;'10
@r9319
ACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTG
+
/!<5C@D;+@)#*$:9-%"8D75='+"C3>',!C'.2#>>4BH
@r9320
AACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAG
+
G&$'--;>E@">*CC,+)4D>G0>)2-(E9"2%=/-H2@E>D5B''6
@r9321
GATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCNTCCGGCTGACCAGCGTGCCGGACAC
+
/&;1-7)F?1=C.:E@%?B?"1,'4%7<)/?!6@1#H6:.HAG7'6$)>E6/63&*H@="*,8-B,9*E@@DDH")?<%%?/#%/**.H%%58?$0)8B2@9!<F:-?;#DG;8-!6>3H,14#*1"A@;C'>!;=(;H);$&FB-:-:;3'?D0/+-**(<7)=C@"0'87<@*$"6,"!BB
@r9322
TGCAGTTCNNGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCC
+
%&$$'&$(!%))*&&&'%+!#+$&!!#$&#$&*$#+&"!'+*(""($&%''**+%)!!"'*+&!!+)$*"+$))&&&""!'(&'"*
@r9323
GGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGNCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTA
+
G8C5CEF&C;,E46D7,B>A.C:49B,/535#"47!0G="C8A<-6(0F'G*;5#@/)D=034<F0&!A/.-+EE3#H6$<'C4C?4?%.1H)$5B1'D>/*;!H<?9<+8:?:2..9BC:68,B"/6=**=#C7':3+3%2B#9+&$?*/,D89-(,#8<?C8:)E:EFG$A2,"D%!@-?36>HG6B7648&@2!6&&6.CC!="!E?>15/F('./%&HB+1,=)7943'4
@r9324
TTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATCTTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTNCCACCGTACT
+
F=."8:#:E041?7>16%*8,>7$>9&.13H<&5//$2(BE7G(3??3'>237?7@G*%=<F)G7+A:(7E&'-?@&*,/G/'%G!CH2F06*CD576+B&8E:1'<$?<H(6(716A9&?>.62GH7=9:GH8GH@C3&-9D=%?;7-H+H(H&>G5:9#5+A+D-C7!
@r9325
ATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACC
+
$>1D/$('-%-#87<7+/.4)7%F6<>+=H4";!!.H5E++@/#4$#EB=5E=*:'+&.GE1@2+)4>-:8E6C82.64F0-*H3?9AB<?A,E6/3F@<'4+B/AD-B9F;G)85!,80G$4F-C%3#A5FDH4
@r9326
ATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCG
+
3,F<66:!6?!<C2DBD.)6+0BE1,G>#))4,C1).*5<")6>*B@$H43H%'4#)=<?%H=4<HB>G6G0571'9+?>?4-B(:6<5+H1?;(
@r9327
TGTGAGCAATGGGTATATGCAAATCTCGTTTCCGGAACTCCGGGTGCTATCAGTNTTTATGTTGAATGCCCGGCCGAACTNGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAG
+
#-;4*7(#@FG7:E=F0=F;=H)@*6A;C349A0?;,*,8/F35#?3A9C=79%)/8D%B56'?F-F5&**!&6$2.(18'5.&&&1<D,+B04017-D$63-C12)5C#041-56>D44=&6@98(/$G=*586$@B!;3;*4).,@2%)2+A7;-=C8"@66:;G%,1H
@r9328
CTTCCAGCACATGCAGCTTCNGACCGCAGTTAGCGCACGTTAAAGCTCGCTCNACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATNACCTTGTTTTCCTCGCACGACGTCTTAG
+
=';H&">#"3;E'0/#F=?8-;6$,EF-3977@;4-1'"8A5.=H)9.@9.-&FE8)&?.'D@4@6=B3%#(?400<=G-B-!(,7C*A=7#09E<B##!8B,980D$&8@9+@9B6
@r9329
TGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATNACNGGATCCCATGTGCGTGACGGACATCGGGAANCGCCNAAGGAGATTATGTACCGAGGAAGAATNTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTNCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCNACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACC
+
,&=BC1-?8H#?1(;634$&!:+#D&-3$=>9=E?<+;*GFC6,41<6-!!8584A$A$4!-$D&#F5(@C;@)%><35(@E/0!(2=1*940)%5B;)%1#*;DC&6?#.:F/,&<+:%:2F;-,;).)$8DE0=87H%,/$=;FA22"F.%(5/A?7@/:7;*-.@F&)A,87'2?.84,:AD+:AC/>@;>H@!9D&<)C:6@#HG9*,GG$,A";%-'&9:'H=,%0C$7G<4D3("6G#%BAED/%H>55,9B*B'G+36$(-B?BF*7&A9<(-?G8C&?9=>A9G.>->(%4"F54C69)C(2!5&!B4=#-6H<FG>.H=)E(-8#0B&:".;$'E4$0#3?472/$C'B,F-GDFD5#E"$&"(.,%D6/!<&)B<2D=$.@A7;>/1&&=D1A5@"A?>(ED66.!;F(B0B'*:G>4**H
@r9330
ACCCCTACAGCCNTCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAACCCGCCAGATGTTTGCGCAGAAGG
+
25)A:-87?B%:&G,$G59*'D8(H#D,'CE-=3(:C$16'>>+'>$-E;?7*'40E$:2E<?".A</'=H.,4+5(@3;=HD=
@r9331
TGGTCGTCTCTTTCATATATCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACNCAGGCTCTCATAG
+
A/E:F;G#AB-,<A"!*15'?8C8:)=:/BC#"@H.*'<6A/C$4)%;C/$<")-HH4:A=9-'.1%0G?B)G>D/#98A$5"*,:@=2;.H65(,:434$#"+.5A/-7G95,4#;FD(<*1+.>B9)/<>)D=>*%A:F?.6!F.!0%"C07'.63=2/8*@'=B-*-:+3
@r9332
CCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAAT
+
#+#%!"%##$&%)&$%%$&$)+!!*&""(!(#&%$$#&)&"*(+(
@r9333
ATTCCACCCATAGGTTTTACGCANAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGA
+
992;B,2%!G,,.-<045,/(,!901GH#$8DC$%6H65-D)5?@7B,F>$;*5;);!8"CG<1DDB2-@2"?5$@8.D>.8=6!&%@;).+G8/+FH;1F=-)8*$.()E;9+A&#>&"&
@r9334
CCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCTCTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAA
+
@272H)7B>0<!'!HH3)26HH,"+,CH=322B.%<#:<,3!'+E&G!*A??F-1C4/8$"?,'?!,4*>$$D%4B19HG*=.<4E4/)%A+..3/<38B?/?#BB$83FA!B1/00&/
@r9335
NCNCNATNATNTNANNNNTTNATNTGGTCCANACANNCCGCCTTGNTGCTTGAGAATATTCANTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACNTTGTAATCTCGCTAAGTTGAGAATC
+
$*"&#("")&"(&))&##'*"*'###$#"''%)%*!!+)(&%+++'"#(&$#'&#&#%&"&!*'%%%)'$)"*(&%+%!&%)$%"('%)")*%%"'''+#&"*"%(%$#'((!##&"&'%$+$+$*(')%$+(#$
@r9336
GGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCA
+
.64CAA<D=!2*-/31%?)?"3(#,-;,1>>@GA;9<10@27=-<;A&2:4#?3#0F"%.93;3#9(9,+@"B&/(#6;D):9D1<;%39CE22%:GH>)*,49$&G*(2!F.-#;1<7%'D$,0%6
@r9337
GAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCT
+
B*(D14EFE)(G$@.',A,538)B*,F<9</0%=,-2?C-2%(:!3+G?;CG!6E.0%,?
@r9338
NTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTANGACGTCGTGCGAGGNAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTACACCANCGCGAAGACGATGTAAAAACGATGAATGCNGGGAATGGTTTCANCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCA
+
%="7H?>6->(%68.D2C;9"39'43?84.+/EFB3@3HA?"H+:;-/=%F:..;%6537:=D;G4.?5*":/.<3735FB(:EB7$*801&,1.13/'G#7;;'=5'?F69;5*9G4;?)-H.,":#//%.G6&-17%*".:F:*4*37&E=!HC87,.1<%*48!'$@7!';=1/6FC6>5B:>2#<8?.5/9=!BB4%,@:&-+*<!/C492B2*%%7-.4;3DEF$1)F$9@F"/7;H+=*4575%<?8B$'E'(FF2/6D9D'@+63A,0.)4&21*:5$&"!*483C.&249/;$->'-12:4&A.+17
@r9339
NTTNCTNACNCGNNNNANAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTG
+
"%#')(!$"'*(!!$(%"'+*#(*&&)!&###'#$&$!+#(&+(&+*'#*)#&
@r9340
AAGCGACGGGCAGGTAAAGACGTGCATACGNTTACATGGATACAGG
+
/2%8;@9;0.;>F,:#7.*2>A.=2G>F6B'C9/?.';</A(>"<!
@r9341
CTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCNCGGGCAATGGCAGCATCGGACAGGTTATCGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAATGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCATGGCG
+
,3F7B>1,'=76=)1HG;<-@#7(6*0<-4/G@84#=%:*1:6-24!=;4':,GAG7(8GE0@)A<':?F?8/:(:BCA-+CGCE)!=F+E5.A?7"+,/A946:4B/&(:4"8+?7%7"$,0GD)<.D;:92+,)(F"C%-A7*C7/,C!.BG/")1,.7%>$2!A)&812?78H*A=9#.C!7=.4'*.(6&;/:BAC)6@#)*+(93+<;@*5'G4
@r9342
ATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCNGCGTTAACGGTGAAGGTGTGTCCGTGTGAACCAATACTGAAAGAATGCGCATGAGNACCGATANC
+
+=0!97#F=$'.1',?>4(12-/&G#.H"(">!<=#:8),+G>C.&4G+4@G&-3)59=2(=9.3-'G=%*/G'5!6%(-$A$.D6)5,E,<""+"72:!!!)1#<70'</
@r9343
TCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAA
+
%==2)"/?:@".,2.GC;+(&@")+".%<8D"4,7$;$>H1$)4/CB#@==C<
@r9344
GGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACNGGAGCCGACTTGTTCTGATTA
+
;*496/7A6C5>1(E<3%*3>6$G346(1B,"6#2.96#AF@%,F:1E+<:B5@3-%1>+1$6H='(/6E:G+&4H=,$)D8HA.<0B5(;<<.=D8A:%4%.'<25&GF(?H>#-3@/8H'#D<%"A85#?++8-<*'*583:&C>20,!5'1'/8E0<1<34C=0#>(
@r9345
AGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGNAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAG
+
&'6.=(G1?5H6A0C4F":2(A6+H-%'%:8,?'>0;@!1C0+!&,G$=2/;#G3A#;HH=$;+8?E>7:)'AE3"&#B:/B3D%7D'*8<:7?"=;H.:4/3$H/+)6+!1A+,F-6@'#G5#B2E@$93@8"F5-+!/@@+A=""(AC%F3.B03+%/?)$C1>2='7+4BA##7;:H/1:#%:;#+5@-9=8-.F'"+B=/30=@4=D3)=A"H6':52D7)%0>+53*#)(25?;)AD#"+6;-8</1"$28.;=/+1'A@5/998,/5$%5<477)0?@=!'48)/)+DDG()0"E@FG-:
@r9346
AACTTGGCTGACGCCGCCTTGCCCTCGTCNATGTATCCATTGAGCATTGCCGCAATTTCTNTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACNCCTCCTTATTGCTTTAATTTTGCTCATGTAATTTANGAGTGTCTTCTNCTTGATTCCT
+
?+7?8=>2!D.48%%B1+'5G=6C&=+**+0C,F1G><B4)"*-;?8;+!&59!(.#";3476>3/=AB+%ED9*%<$"%#8D.:@"15.,5EGC$.@*,3H6$!4'9ED&6.):6*5,@D8.'/H8.)GBA"=0&&*7F:H2%EC1%?G'$*''/
@r9347
GCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTCACTATCCGGAACTGTGTCCGGAAAAGCCGCNACGAACTGGTATCCCAAGTGGCCTGAACGAACAGTTCGCCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCTTC
+
6!@%-,AF)1>8!A5F#&&=A=#>:2+6)=.?=4&DF+$.0#B--:-/'$6,>(F%,E>7#(GB.E:A*4>0)/;#<+#EG9+?."#>)G(.9@@H!*?640FC;3534/!5FFB#>,)()6(C@.'3$/B9D2=!H:C.>&?"FCEC,&6F9G0@+B2+<='@+:+:2+6?=9CF+/='.9D%-?38-83#0F.@?8B/F
@r9348
GGTGGGATGCCTACCGCAAGGAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAG
+
<H2*.(54H06ED)5*&/#%%71()GA3$?B""<#22".=)42(2%)0:41/?-A9B45,@B-C$*+(/<#>!%@F8,/:".H
@r9349
ANANATGCGTATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCNCTATTCTCTCGCTGAATCGCAAACCGAAATCNCGAGTAGAAAGCGCACTAANTCCGATAGACCTTACAGTGCTGGCTGAATCCCACAAACAGATTGAAAGCAACCTTCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGNCGAACGCGGCA
+
$"'$$())*"%(+"(&&'($+'&""+$"!&+**&($!)&$)!&+"!%()!%$"$%"(%%%(')+#'!"*!'"$(#!#!))*&*!)#+($%#%*%(+!#"(%+#!$+++&''$!#%#"'%&"*!)!)"!'('$'+#+)(+$("&*#"(&+)"$&(&)%)(&&$*("*&!&+*$*'#+(!+%('&!!!)'&+!!&*!#$$#%&'&#&!"&%!%*)!&"'
@r9350
ATNTTNAGNGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTNTCATCAAACCTGTCGCACTCCAGAGAAGCACACAGCCTCGCAACCCATTG
+
$!""$%&'$+!'#!!#+(&+)'#$'+"$!!&)(#(+$*"*(*"+%%'!")!'&*()'!)*$%$$%+#!&%&!&"$)+*+'''!$*)#+&%#++*+
@r9351
TTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCNTC
+
D@E(*-.+9$745!3".9-'3:@EG!--GF08FG->A%56!-&B?D-6&,1#-0F$0836:
@r9352
TCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAG
+
1->"*:2/$#'<+7>:6%DAB*G!?1#'<H(%1313H".&=:;B&.F.7E%"(H+"%=4<10+?@7C@=46&AA03&=3,:('FFC*&6D@B7)A;=5&$$(5*@>)
@r9353
GTTGCGTGAAGCGNTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGT
+
7+95>G5+)?)/>,),"+.18=8FA5./A<%0896+F'-335<E&"AF/.D?,+1%,BC2$(03$(?.5&%%+
@r9354
AGTGAANGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAA
+
'576,74-4!6%?*39G$=E-2A&0G=B@*B89FDG?>@AB(C)@,,48<9A,BD7,54GA!9?A%FA@2%>0AE:9'%8=.*(5E?)(;)>3D"96&A,*61.#8-A"G
@r9355
CAGAACTGACACAGGCCGTAGAAGTCAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGAC
+
.'F%"F(D1H;?-!8E)-.,F+#:@//6/.>,8E3""=E>F>12%&.?D"G%7:$+G<#D5<@+)F39$D@'*H7:"*%;5"
@r9356
NATCTCGATGATGAAGATGCANACTGGACTGCGACCGGGCAGGGGCGGAAATCTGCCGGA
+
#$+'!)#$++$*#&($"*$*(&"!+%!))'&+('!$)'#+*'#&*%+*!('(*$#+'&+)
@r9357
ATGCCGTTAATATGTTGNCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACC
+
/C*B>A59E/+<>>C83*C>/6A@DH054?#B,58-0E&4*#*/*(!93???(H(C&-&%<(:%D&:>"C*%=F(A1*FCA@:-!.)%=D4G'D*:7.<
@r9358
AGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATANGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGAC
+
7E;!7>E*44B77=F*@2?=C23EB,>)>@$CE7F93+0,.768B)%:#H0)0C125$D*!B!1)D$4B&/).1+*(H7A&G#-A9&:.=4"3"'.1(559.2)78A2"8'F9+>HG6B(/1+;6
@r9359
CTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCGGAAACTGAGCGACGG
+
H<&9BB%1/6$->'#-5%7-!!H@0:9385F>/-C06#,31F"H@@7C*=3.%4@HG.C,1186+2-14%2=-!FCB298
@r9360
ACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATCTTACTGTTTCTTTACATAAACATTGCTGAT
+
++%+#)(#&!&)!(%*&"'&(('%(#$*)!(#(+(*"#'+%(())*%"$##*$&(+((#()*$)!"%++*"&+#&$"('"*)$&''*")#(#
@r9361
GNCGANNGNACNNNNANGCAANCGNCANGNTNTCCCNNNCGCCTTGTTCCTTTGCCGCGAGAATGNCGGCCAACANGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGC
+
!"&"###*#(%!#$*)$('$&!*&$"'$&)'$')))#)*&')(%+%*#!!%&%""!("$'!'*('(!$%)$#+*&!%("#$%+&#"$""%%+((*$($*!)($#)!'#!&)'++$'*+'))*$*)*
@r9362
CGTTTGATGACGATGTTGAGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCNCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGA
+
&H73(((+GAAH5'.31=B@(=!F(=E@@-8'D<@61"=C?-.7)(83C;/1%+EH4H".+7<A;6=H(23;?+!(>':1#889:FF)/>/)'0"9A'#3'1CE,A-5*2$%C>)06C%:D.1$?96#G="E88$;9;F+$-*C9A>87F
@r9363
CGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACCACTATCTGGCCATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCANTCCACACTGCTTTCACGCTGGCGCNGAAAAGCCGCGCTCGCCGCCTTTA
+
E)9C/G8-1H,(;?=FDD?9G+GF>-"FE'&=='"#=+7?7GE97;?)/.>#**'E%HCD?9C<!$6!-<@%+2DF3289,<9E?>5CA'EE(=&5(90$"5F8%C8#-*0A!8)68?:06(B&2!"#$9F%7.A?><$.G,&..F87F+)3<;3;&"*:>,41,:E0"4/+,G!C-')=F4*A#",*#.A1&/E$H22D3DH(-;
@r9364
CNNTTTCNANACTCAGNAAANTGTNGGCNTTGTAATACTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACNGAGCCTGATGTGGTTAAAANACAG
+
(#")))*#*!&))&&(!&$(#)()$)((!))$+#&#!$"!&#)!()(%'"&)%$'&#%'&()!%$'*)$&"&')+!%'!'(%#++))$&#"#($"%"#+**&
@r9365
ACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACNTGATGCTTTTCGTGCGCGCATAAAATA
+
(6?C,*(G!C8137-D"!'9:13(,$-4*DB@67005=C'@1/2DG)2@/5-0(*#7);D()B<GD"D710.E&H#B.1@:D(>062"%@F;+$;4"'#%(-&1%+4%AFE1@2>73FGC:8CB3,!2$C-/F069E%63EA<%/H1H7?F;E5/B13CG90;=0*)<
@r9366
GCACCGCATCCAGAAAACGGGNGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGTTGACCA
+
%?B4F78:<>B)6>D5';'8E1>(.%=0B*/0A93*=)?:=##22F5H;D=(1);:43>1+!&=')38'?7D@-&/+!(>56#G%G&-@"
@r9367
CGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCA
+
9)D..5B4A@2?G,"&41.25C8"+A9*&6)D*H#@D.4=$1599A,,;E*0+!"/
@r9368
GCACGCAATGGTGTAGCAATAATTNCAACTCATTCCCCAGTAGTACTGCAAGAGATTCCAAAATCCTGCATNTGNAAAGTCATACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTANCTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATAC
+
+($'"*#+")%$''&$'"))$"#)!#($'!*'+*"!'$%")'"*!+%"%*%%!'%#)%'$+("#$"&%%++""+&)'*+($+#'''"*#!!&)&'"+%*"()(*&!"#(&+'!"!"''!!*+)((+)'(%#+"&&$&()%"')"&+&"!$"#&)&&!"%'*)$'*!$$$"("*&"+()!#")*($#()!%+##%)
@r9369
CGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGCCCTGACAGAGGTCGGTGGAGAACGTTATTTTTTCTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCA
+
H4",G=CH(!?4+?D1,+&*4A#+-0="6+3:3!B+G!)EE%.H5'4G><"*%63>!,456$9D%=B%'C8)&46,3G$H!C6)G;?@=)7<;78@6,2($;'65D<9H=C2/G#29B93.:;B2@"B'?E6<@=@-:3:=&G.4!
@r9370
TAACATCCGCTTTCCNAACCAAATGATTGAACAAATTAACATCGTTCTTGAGCAAAAAGGGTCCGGGA
+
!)+"&)%+$*$)$#)")(%"$"**('(#('"**+!'$')'$+"+)$'(!++*#"*+##*!"()#!$*'
@r9371
CATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACCAACGGGAAAGAAGCTGGT
+
A$F@F?)D2@,*$7A32/EDECD-(#GG<5/2HH3;H-2-"?69$#0)&)E3)"?<<:H-<99#/&7A(99C1,)*',;A*A85E8-FA,&,'A*G$F<?+=.(/;-)/AD0:/!='@;.6/
@r9372
CAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGG
+
H658;"A+D+$8F@72?$>'-!'+3;.83':+2>&@>(&C%2-:ACC!::!,B9(7-$3A;=,2364?8"!+B,+>*$!C"?:4%!H$&!#1@+<:4..?89@#.#6D,$93<>7-)%/CHDC895@G!8G4"@.+2B")%E:)57DG<02>1'(4E4C'$75>':24:
@r9373
NNAACNTAANGCTNGANGGATTGNANNCCTCNGNTANNCGTCNNNN
+
"$#!!"$""$##!"$#$$"!#$"#$"!!!$#!#$"$"""$"#"!$!
@r9374
TTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGNGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCT
+
F=632)E#H(A1EA?8'+*3)*66B6=A3@4*E3E;/FH##/6%(">>*,+15$-G33C,(-'HFH;A(173<C!:E16)()017F0B0#H;+3BH:&/F;"=B,%0<E+D'6C6,G,A
@r9375
AACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGAC
+
)H<"4/,$$4-89>!&+)?E781D@A#-9%"D2&8!-F+8
@r9376
TNTANNNTTTAATAATAGATGATTCAGCTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACC
+
(#)!%!%"&$)+#+'$'+#$))'&)#&!("*#$!&!'('&%'%&('((!+#!#'*+!%+&(!$$)((*$)!"($'*%$"
@r9377
TGGAGAANTNCNTNGNTNGGTNACNCNTNTNNGNNANCCTNACNGCTCAGNNTTNCGTTCNCANNGNCNGCCAGCNNTNNTGCCNNNNATGNNNNN
+
#$$#$""$$!##!$#$$!$!#"!#!"$#!$!"!!""#""!!"#"$$$$$#"$$#"##!""##$!#$$""""#"!!!!#!!"$#!"!$$$$$!$!"$
@r9378
TNCNNTNNNNCGANNNCACTGCGNANNCTNNNNTNATNGCATNCNNNNATGNCANNANGCNAANNNCNNNNTNCNGGNTNANNNATANCNNNANNTTNTN
+
!!"#$#$""!$#!$!$#$"$!!#"""$$#$#!"!"$#!"$!$!$"!"$$##$"!#"$!##!$$""!##!!#""$!""#""!"#$"!$!#"##$!"$"""!
@r9379
CGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAA
+
D'9,&(>*(<$/$1F-2@@5.7)=;5>2)51%(+/!+<(4,&7(*,6E
@r9380
CNATTGGNAATAATTTANCTNGTCCATTCCATCGGGGAAA
+
%$&)'&*$#(*)#*#$)"'!%#+*$'(%!%&)!!+&!''"
@r9381
TCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTT
+
9&-,).#G+1H?4<6;)!';$%9*DF2F<"(9),-?(;E@?G18D6'A&8F54(07D/"*<:)9.(E0,<;@D6B/$-=-0,,9?00B8-1$&;C@CE<)(&3<,*2#?)70G?41H(DB;;G";+5+%F(5%8<2'+5<8<,.D&-5/)H50-'C7'*-FG=)/'@5A1%,1()>>G
@r9382
TGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGAAGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCCGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAANTGCCGGT
+
&C$0G/"CGE42&!>@B,E(504C81B@!A)26F'<)0##1.0#CE-DD%//.6:@99=EG5(>1%%$A-#401-AA&F//#5:!:2:+DC0G??9>(=&<8+G(H,4D'#5:(>&&50!B?;8$"0<%06>;A<&(/>',">H642>H32$;'(!F19/8/09@C-1$$9=!%4D@D6+;0;$.",EE>'(('G+9=?6:;-@G%F>1.?2$-:H:0GH:E*.(>!H>(%$;EF%E3
@r9383
ATTNATNNTTGATTATTATTTGAATCAATTCCAATTNCCTGAAGTCTTTC
+
"$!")((*#+&&"$%+$((+&(##&")+$%((&$+#'+)*$*(()"&'"+
@r9384
GACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCTTCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGG
+
-7#//-6F?EF)?B6"#(<#??/8D7C4D54!'+8H&C?,<@"B-D6%F&$BDC0B6%H<,9,:#7!&(,1D:3:*#:A&G$?:*G;#E3/-7?',(4B<?,A=/H01+1.("(2;/:%0=-56+
@r9385
CCGTGAAAGGTTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCC
+
D"0(7(.;>#&48>#4"5#2A'0'A5,:(8E(?7''H#F*0C$<-(6+('
@r9386
CNAGNTNTTCAATGCNNCNCNNNGCTCCCANTTCANNAAGAGTNNNNGTCAC
+
$!*#(')$*))%%%(*)!!$##!()&(!*)('(&$##%($"&#%$!$"*&'+
@r9387
ACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCACGCTGACGTTACTGACGTGGTGNCAGCGACGGAGGGCGAGAAC
+
$*#+'#(*&$!)*!")'*)(#$%(!)+))'&)&$&''+''#!%(#*&&+&+*(#'$"!#('$&"*+&%*!&"*$%*)**'"(#'*)&
@r9388
GTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCA
+
&#$#9C0;$B/>A!-8'3;H$6?(H%*?$27!"ACB?/,491,%'3@>.:@BG=?G??*=A/=G!63)1
@r9389
TCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATA
+
F3?2A7CC@8CH/3"5F/6!):8,2<=<3@CGGG>-3B;E8?#D7;$
@r9390
NTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTAC
+
%%+%!'")&$""(%*+(+'&#'&+(("*$$($$!)!%*!"&#$#$#)%&%
@r9391
TGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATAGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCANGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTANGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCC
+
$GG,@1&-H=G!C>C+=&7836&G1F&8)'2=5=7%:G+2)G,+D)/;*2*=(&;<-@:A4!47A.+4>2&!5>9F1?G,0;ABF!*9%@"5G.B;,;"2"D,#3-B/=!H#0(D24GH-A-670D$$)D9GH"41&(E.3&,*FF,H(B@#!8$7#3+E$5,HC9)4>4:0G/8B4#=0/%G*&E"@:F6AF7>!2;F0?$5$>.?'7&AA(>D>/,."4/@GF6';'4!F1'%)A3B?%9<+.>A"%80F'/8=497F0:9A=3<;."!(%,D0%$62,<+"$7')750(3-,B@**5@5<0G-E$.2-7-3D6;09$*<)!?F*)@;>>:6'$)()1>(51<;753>*#>+D;/1:!)G!G;G40%#5&&):2.9$F>)
@r9392
TNTGGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAANTTTCGGTGATGCCTATTNATTTAGTTCCAT
+
$)&&+#(&*!!$()'&*++%**#&'#"")!*#")"'(#!&!%#'!)(&!")!#&!)%%%#%*!+'!&!&*)(#"""(!&'(*$!)!
@r9393
GCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACTCGTGATTTCGGTTTGCGTTTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCNCTTACCCCNACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTNGCGGCGGCGTGTTNGTG
+
F6D..=9!&!$57&!3/:.,"&&E7(),7;A?:*G'!A7.7'C$:D9A$"?!<A$3)3595@!5D+#).0=2"1$?/;AH$CBDG?D*+:B)E.%19<+GD@1(.(B1'G@:)%&A!7<=.%7=1)AFBAAG&D::"/@@6*BH<@(,>?+4A&H"95G;<A>4!(/G=#9G0A@(2H6#1F#%0=->$;A#>H@@8?.8
@r9394
GCCAGCGGCTGATCACCTCCTNCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGNGTGT
+
25C/=C;,.F#(;%$<D*43'!$:E=/3A+5G'+$&1/%#?>?B=)1#D7';A2FEA*2G2((*820+"3,!/;<H-!+4#
@r9395
TCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGG
+
C8E5(DGGC#38D,-:57'=!B9F8?HB?:,(79':E8?24EGBF>9&'@C09A&D"4%C378@;$7.,E+<00-5H0"?!6)B)%<(16CEG#H6E&.+%H2#;G+2G:"8%B'7:&5G2A5',BEE$(-4AHB5G91)/HHH"?!GH+=
@r9396
CCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACNACCGGATTTTGTAAAAAC
+
0'<'+7A(<=,2A<DA1?4BA$9F>"7G-E7-DE%"A,>CG*+3>/-B$(.*9644$$0%7FE
@r9397
AACTATTTTCCATGAAATCCATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCNTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGAGCCATAGCTC
+
A&=:H<=4EG.2"-4FGH%$+#;"0FG1+*A)?1)7E*)."BD%;"B.73"2)A>D5G,D3C3/(=!)F1CB(83<@D?"B0)D)33&7$"+3DB6"!9161F>DC*5EA*8#9.BF0E,9(39&?@0,C:0
@r9398
AACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTC
+
B884B?90HF"F7;45;0H&H/)1"=9G2&G6<<@6$3+;
@r9399
NACCAACNNGATTNGTNNGTGCNNCAGNNNANNCNACNGNNCNNTTGATTGCNNGNCTNNTNCNNNTNTCNNTGTNTNNANACGANANNNNNGNTANANGGCTNGNNNNNGTNTCNNTANCNNGNGNNANCCNNCCCGAAANN
+
""$"$#$!"!!#$#!"!$$"#"!##!$$"$$"!$$##"##!!!#"!""##!!"$""$"!"!"$""!"$#!!#"$$#"##!!!!#"!"$!#"#!!##$#!$$$#!"##"#$$!$#!#!$$!$!#!"#!$###$#"$"#$"##!#
@r9400
CCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCT
+
F6-.,597HE/5892GF*208B"*:&B0)0?&2(/0$!H(=B-9D<C1@#A!%:/7B!5&A-EB!96/@5
@r9401
CCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTCA
+
A8;2!>(C41?+47-07C'#C;6E/5F:B'2!.%9&=(D6*BB<2<5=B#=0:+
@r9402
CGTGTGGATGAGGCCATCAGTAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCTATCCCGTATCTGCTGGGATACTGGCGGGATTGANCCCACCATTGTGTATGAACGCTCGAAAAAACNTGGGCTGTTCCGGGTGATCCCCATTAAAGNGGCNTCCGTCTACGGAAAGCCGG
+
5F4D%25":,?195)&.H6%AE88**9E9/D>:1?8*ED5>A@"%@?&AHC:E'2(7C7<,@*2BE"%3B22!,=D31"7H?434=C8H(5-#"2'A@57B:+H.<7;AD1D,>'F#1;1=#6$"8<.*0)G(7+A9(8@%98*'?)@>8<#.F93F*B@5($78D@C4!;6&893:B<FE,;
@r9403
AGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCT
+
26#+*8"D,43F:FA)?5C5B>(F0=)/'C,%(E:(0D(-,E;<72"E","=4"<3F7?0.H))01B=(>27*-274=1E.G&)),1D3!7*-4")@->G%@/4*!EH
@r9404
GTGTCCGCATCCTCAAGCGCGACNGCCCTTATCTGAAGCTATAGCTTCT
+
5!<'7C2F@)"4,<7-($.>?(("9>2.D.>G0?*8;*/3B$<%/?*18
@r9405
CACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGC
+
C/9;)D5?D#$#>C&;#)H(9;E&:6B;3A'8G;+$"":F@,A6"1#"-8G#E%+;H)4?1BBE88'!0F%D*==D?<<=%)4/(?087&9
@r9406
GTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTT
+
G2.B:@B+AF.DD0'8&8.48<($1'*%+!2%;5?F1(8/4;&B"5:)4?9GH?CE-%6F,8*+.4F<!E29%91$/@$,21:?8<,=-*:H=);>B'#<GC%-;5=:<<":*9!'*@*:775"2C?6,F"8-)H@49,5>?0./0<#;A:)<-B)D(9B868(?7%@(&,AB6>F5C;<E,+90://7>#57"))&G(;?7'
@r9407
NTCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTG
+
&/A)CE7&+B+9B(7G(!9+#G9(+%F=3,EC4?#F;F;>:B1A:6E&
@r9408
NATTNNTGNNAGNANCNTNNTCANNNGTNCTNGNTTCNNCTNGTNTNATNNNCGCANTCNNCCNNGNCTATAANATNANCNNACCCNGNNNNNNATAANGNGCAAGANGNGNCCTNNACTNCGGNNGANGNANNANNGNTTCNGNNNANNCANNNAANCTNCTNGCNNTNCAGCGATNNGNTNCAANNCNGCTNCNTGNNNACNNNTCNGNACCNANNCANTTNCNNTCNTANCTGNNAGNCTGTNCANAGCNACTGNTTNTNGNTNNCNGCGTNNAGNNGNANCCGNCNNCNCGGNCNNGCTGGCANGCCGNNCCCN
+
"!""!$!$$!$$!"$##$$!#$""##$"!#$!###$#!$#!!$!#"""##"#$#$""$##!"""!!!#!#!#""#""""$##$"!##$!!$$!#!"###""$$"#"##"!"$"$$#!$!""!##$"#"$$!!#""##$"""$##!$!$"$#$!#"#!!$#!##""$####"##$!$$$!#!!"!#$!$""$!""#"!#!!$$"!$!"##!""#$#$#!##"!!#$!""#!$!!$"$!##$$###$"!"!!$$!"!#"$#!#####$!!!$"!"!"!!$!"#"!$#!"!"$"!!###!$!#$$"#"#"!#"$!!""$##
@r9409
TCATCTACATNTNACAACGTGCGTGGAGGCNATCAAACCACGTCGAATAATCAATTCTGACGCAGGTATCGTATTAACTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGG
+
0+80AG=6H%@#4;61*>5&.DHFAB<A</><.A8?1H*$4":60<)=<,-@=E=7:<1BFD<=:4/61,H!6>0:46BH33D8E(1%07?5*"D:9$7"4AH+3%#0%#-6<)=GC.4"),99B?C7D$+6-C$!9-6!=',
@r9410
CCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAAT
+
H4H0=A8D1>,*(/1'G3,;-;?7*8?0)4-H<(3*>6H2&!$A(?A-4:,$%GF4%B$5F9,,2'!$8(
@r9411
ATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCATAAGTCCAACCCAGNNAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATA
+
31&88/B2@-3G*?D*6>2F9<&8AC2&<H)7+A'6:="+!<"?809AG6/DA+'$/GBC<=?(+1$%+++'#?6.#:B6?72B3>&)0..?+<1A'E0D,!E&4&%B&"CF@&1/7">/7,88+&A@#+E+#$?*?5406)!:5GH=!AA"=@@-#$BA,8,E*>F%H//1%A&"//H=1!-A"A5#'F.0A'C(1+2@+.0+.:$4F?HH+$'8C(+='$/(!<$57*A681GF!*+2HHH4%:03
@r9412
GGNCGNNNAGTACTGTGACGATAGCTGAAAACTGTACGATA
+
*!#*)$""&$$(!&$(+'*"++*!#()*#*$'$(%"&'!*%
@r9413
TTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACNCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGA
+
>'#0"3)HE)=E@.C?HH8CA3&((0&@#$*1+18@;B3$!DGGE((F(6!H4G0F+D!H9=H5;?$?;%E&+F8E&C:H-B&#+G%2,9,'"-430F7F&E:><=*7;")#>
@r9414
ATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTA
+
D+&%;$+*A::,%#/'0<G,<D%A6@#8-0'40$&H97&,8CH3":%)6E5
@r9415
NNNANNTANAATCCTNCAGGNACCCTGCGTCGCTGTGTCATGCCGGTCTGC
+
&!'$"!"'&%$%*#$)(%(*"%)"*+'&#'+#%)&"(*+(&"**#%+$$)%
@r9416
AGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACNT
+
239;=8=1$9H2(#&3>D-9G"'(--&;##AGG"CF/#"6#8?.?H
@r9417
NNAACCGATCTCACTCTCCTTTGATCCGAATGCCAGCGCCAGACATCATATGCACATACTCACCTGCATCCTGAACCCATTGACCTC
+
"&%+!+'%+)')*)%(+%+###$*(+$%("+%#+&"*+"))$%(#"&*)%")%+%++!%+)&$!#$$+#$##(!'%+!)!)!'*(*(
@r9418
TACGACCGGAGCCTATACAGTCGCAGTTCCCCCAGGCACTG
+
10A:C=F%)&3H:2)<8A/'"(&;,B(:5E=)=%"&(!"&%
@r9419
ATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGAGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGC
+
BF'$C@E1F8?(?/;EE<>-06H9H.!HB2,@GB%->?<H'()G9,E/HBG%CEG+CCH4*5#$<3-0*>$'AB/*7B4)$>3'-!;:F/G5-B*),0"D;=$<#-2@'&1+,6*G
@r9420
TTCTTGACGGTNTGGCNANANNCNGNGTCANGNAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAAC
+
'$#"&$)$("'")!)$!&!(##"#*!%'&#)%!+)#%)'"&(&"#*"$"%)&+&&""#%)$!!(#$"+("+)')!'#&""!#*('&+%%!%&*!&!&!))&!*"#&(*'!!%)"#!(&*()'*!*+*+&(&%$+"()&%($))"#+*))%$*#+(&+"
@r9421
GGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGG
+
,E#)"C!0HB#-H(52.#H(6&8;1E/D*:>/:-0,'95(B>)3E?16--H:=+B#%4#>?/7:BE=@726%#.@(#>:.H#9"==@"0(0D%><$
@r9422
AACACAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCA
+
*03=D@%$@1E#<4&D9C9"8<,@4G"*#8=68-'(DG&A%.&#&)H.H;D51C9+=>C>,4F?9F'D'<
@r9423
NNNNNNGANNCANCNNNAGNNGANTNNGANCGCGCNTNNNNNNANNNCNTNTTTTNTNATCNAGNNNNCCTGNAAANCNNTANNNAANGTATNNNNNNGAAACNC
+
######!$"!#!!$#"!$!#!!""""!##!$#$!$$#!!""!"#!#""#$!##$"!$"#$#$"!!!"$###!$###$#""""""!#"$#!""!!"#"##"$$""!
@r9424
ACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGNAATGACCCCGCTGATGCTGG
+
DA+E%<*+F5CC971D5'0G9*8',.:5A;02B3F655)06;F1@!.,&300C!-
@r9425
NAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAAT
+
15:54#.>("8:??8%;0$-&7=$9+0*;42$B)*C556@@8!H
@r9426
NANNTGCATNNGGCTNGNGNCNTCCNTGNNNGCNGAGNCCTANGNNACNNTNAGGNTGANTGNNNACTNNNNTCNCCNCNNNGGCNNCNNGNNGGNGNN
+
#"!$!"!#!"!$$$!!"!!!"$##!$$#$!""!""$$""#$#"$!!"###"##!$$#"$"!#""!##!!!$!$"!"$"$!$#"$""!$"$#$!#""$#!
@r9427
TTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTC
+
<)+?4F$F5G>.F;;#G5<>;),2G?-D)6<8"D3DA+7)(+98'.2F8B0"B(2E)EG',"/G=<G;,':
@r9428
GCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCTGCCGTTGCCGA
+
,=!4/>7;@B744A:.;F26)"1+")2/6H94;#2D9:5%(94887*C.A2G:<()>D?,4+#H.1<F;H#9?CHC+7B*4B#%B./?<@@=4=F6,.=E?
@r9429
CTTGCANTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTA
+
&F:70?>6(G#?8;@%$/>)%,(//!3>(.!:F*=EG!E$=;@
@r9430
GGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTTACCGTGGTGAGTTTGTCTTAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTGCCACCGGTGGTTATGGCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTG
+
8<CA"(77+25"".(F;-C+@?;(*2%,2>001$(((D4F>.''%<4A015",H&,-/>*D'-<64?CCFF;:"<56!<=8"#4"7.E$?A=H47@:E19@42=568-E"G7#67.B)3'6,@+H?H85(=A(/B+!$A):1'0&?@$H)CB67/04655+?))"-G):9+-6+#:@*@2;C@@11!+;5+2*(F<"9/!@$<G-+8.?74!D"&
@r9431
CCGGGCAGCATGGCAGACAGCCGGTCGCAGGNGTCCGGGACGTTTGAGCAGAATAACCAGGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGA
+
H.&%!@25E39>22$BH;'G+@(/<)'*>.(&7G-)2-,0+5@C?/<::.?@"H#;C59HC(G5FC*!H)C@;?=-2$G*CB-;58<$H>;@8))0/;4AB5D8354!!90B(6,*)+6/<3>>'"!$"&<>;D2EDF@2&G.,G$<%'),4
@r9432
GCACTGGTGAAGCTGCATACTGAAGCACTTCACGCCACNCGGGATGAACC
+
6@'C)*:160:6#4,543"#&3'D(#@-!.#F,*$CE'(%;9#)B="30!
@r9433
ACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCNAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCG
+
*$#C<#2F'=<:D&;!4@G8A'A$0<G3;5&-.8*8+((;=A;GE6+9=<*9;F77H,,;(ABF$*!'">=5G/H$3/%&C9%>8,;!*63<B*;H+1A/
@r9434
NCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCC
+
"GB3",4$5>2.+C3"E"A*35&'2?.%'0!"83?16(=B&?@5(D.?3%=>D
@r9435
NAGGAAAGGGGGTTAGTGAATGNTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTC
+
(<.A"/!;'>;;3=:>?;-&A;B&%!?&(66,(+(/D*-3.$B'%?=$34!H7/?'7!0*)0"%"G2"7,08D#,@#3HF+
@r9436
CCTTAACNTNGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCA
+
?$;G*:=7#69<>5H>D*-9E-1957'?4H-0%#4@1CC367C8D.'EEF><-+%,+<&&.*GDH@!"01%A?$.6$8(C7#6+/)03801//7!=24C'@1(0C>2/
@r9437
TCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGNTATTTCTGGATATTGTCATAANACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCGTATTTGAAAAGTTTTCATCACTACTTAGTTT
+
?E!%)/6E2%:?93GE18;#9D)3GA/(1:21?HE,=8*;$"7"HG<"'E3'@A82!2<:9/"28</.):%D:?6!(8"//&!#3D+/%1!68?#,';C@52+9?'7*"D%9<?'90A<D;,94'7B$A2?&6"A>//15!%8B54<C:107+C$E"6?DE**6G';4(B2'%G?A#)75'"<)A2)A@B<6'!$
@r9438
TTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTC
+
.&0H4-"2;.5%94&)F#>E?%'"&C6)F:"%42=6=06G11;@0-"'=G1/??FA363D**EH7,GB;@'('2G*>'EE/=G+C7/5(H>E/3GA"=.@&4.262"&CA3/=)A;?>+C/(CC150G$,0BG3-)GBC+138'1>A/-(:3*>.A)B,-%:+.
@r9439
ATTCAGCATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTGTGTCCTA
+
1"C@;=59,4#+;4''%E<D97-1/A>DD3)7?F97/93#H?F10=2F-,0%&(
@r9440
NGTGACGAAGAGCTGGCCATTGCTCAGGNCGAAGAGATGCAGGCAGTTTCTGCCGTGCTTNAGGGCAAATACA
+
"E09#("?@'F8+':-1?37A(>D%F2(-<##<%@.&F7!)':F>:6)!-#C'9.+&$C8D>B63"='6)6")
@r9441
GCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCACCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATCATGGCCCGGTTTGATATTGAGACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTNCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACC
+
52C@5(!3F(A#D3A#H.F'GG6$2('(8H6:)/4#@+;).+$GF0ACB7@%'4)C373($(%;5+)2$!!2+3+282/DB:(7A;@6B.>>-F2E4-9=-).,(C-,8@7@<8$!?,;;,34/=A,38F4%;+B8%+>?0/A?)BHB2:.(=2G'A(3;DA3;4/,8-0;H,D7?G4D9-:#H<@(+0AH&%F0;70A9()&)775FG?75&;#2C-9(/2%1(*;@0+4+@H#$9/
@r9442
AACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACNGCGTTGCTTCATCCGCGATAT
+
-E:H7CG(0+(BG)>%3B(BF@+B37,A&/:'B5)%+H2#C2A";+#B$>B7&%1:FB6
@r9443
GTATGCAAATAAATGCATACACCATAGGTGTGGTATAATTTGATGCCCTTTTT
+
D/>@:(+.F<C@F&@&6'G3HE?68#8@AH9D7)96(HC@D%'7(9%05+&21
@r9444
TCNTATTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAG
+
&(%'!+!"'!*'##"'$'"%&*$#$(*+*(#)+'#('(+"+%'*'"!((!!'"+($"$(!+'"!!
@r9445
TCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGT
+
)(9'B""+H3D<.D8%?20F%-E:=7FA(G>(.")4E+?8.B$=?DE89!D?!!+C
@r9446
GTNANNCNTCTGAGCGNCCCGGAGTTCGCATNCACACTGCCACTGAT
+
"%'$#"!!)&('!#('++"((&(+$")$++&$"%"&&("))&!!"&%
@r9447
TCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCAANTTGCAAATACCGGAACATCTCGGTAACTGCAT
+
+'$((&)*(&)%!()$%'+)#*!"'#"(($"**#)&$%($#&'%$"#)+%(!*$&"+"*%#&+!(!*'#$+'$"$)+!+&!&!!!#
@r9448
ACTCCCANCCGAGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTT
+
DD;+8:2#7G>HB;34D"%4H;B+&5&/:(-(B5&"+5DD<33=,G/6)>
@r9449
NTGCATCAGCTGCTCAGGTCGCGGCCCTTGTGACTGANGCAACTGATTC
+
+?'6;7A'19)D)E@2($$3.*1":>H2,$)<#3+7%>A>*6#A+6H%0
@r9450
GCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGTCGGCATTCATCCATCC
+
911%$00D.G;)C2FD:@-B*5G$/@F;D/5B("G:B0*6?5=!+CB/>*/(<2%@,8#>5&F?=*)4A6H%:""88A'6189A'GF&7#B5?"(><%07/5/8=G/;&C':H,A
@r9451
GTCNTNCGGNGACATACGGAAATAGCCTCCGCCTCACCGGA
+
%")%%'&'"!+#(*+'%$+&$&$#'"'&!&!$$&!&)#"%(
@r9452
AATANTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATNAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTTCCCCATCCCCATC
+
#)!+$#)%&'''+$+))!(+'*)+"(#"%$%)"('**+!#*%+#+'+%"%'%&"%&$+$++%*))")%#$&)%*+(%*%(!#)("*+%#)"")('*&&&#$+(&'#"##$!$"&!%*%%*"&!#)$*#!&!$%%)&'+
@r9453
CTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCGTCCCGAGTAACAAAAAAACAACAGCATAAATCATGCA
+
"'*+%&&)#!($&$%*)(+*%!+("!*!""!"#"'*((!&$*%$#&$#!&%!"&#$%(*$"!$!"#*$"$!((
@r9454
ACAGGCNTACGNGNNCGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTG
+
%)&#%*$"%)&!'$+*"((+($&(*))#(')&$"*!&$*#'!+*+&!"$''*(&$'&")'&'&%*#'#)%#&#%%"&$)"$"$*+*'!"&+*!+##)#'#((''))!'+)!$'%&&%&(('+$!*"(""+$'%+*!&"(!#*+
@r9455
GCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTNCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGACAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTAGCCTTCCTCCGTGTCCTCCATGCTGAGG
+
(7F%H5*H<#%12)20+''=78C:H2D;6C/3G?*@!6C:%*B$EG#+G*$:)-!&6@,4-9"(&'1-2E&2!>CG>7D'6A"H*0>?12$>?A7*>6)1.0D;F%%10'07HC%>6-;+%!E@%0@(4?7>@/C-&A??C>>3.&4&;(#%!0"8GE':G1.6'FA:>/0E/=%>1@"-95))<20):D0;25#
@r9456
CTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCT
+
GG3-#5B&F(6;5FAH83(7"-G4/'+-*DG-!250G2(0*/$G$9''@6B63"
@r9457
TGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGATTCTCAACTTAGCG
+
>H2">G:+%7(.A*3A8:5!B4.;0*5A)/*682,?8H>"33E1E1933G7($1,7D&4=/4'H&3',G>6&>><5HB,@94*G@>!3=<'0"*>.-1C##"/$;E9+%'D-!+5>8:.2E%9.95CH"='%!B<FH4@@<>2D6&<#,8-@%0F
@r9458
GGCGANNTGGCTTTCGGTGCCAGCATCTGAGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAAGGGTTGCCCCCCATGCTGCAAGGGTGGCTCCGGCNGNAAAGAATGATCCGGCAATGGCGG
+
)(!)!)$)#%+**+$%+*!)")%!%&)*#(""$$!)'+%#%$%'*"$"!"&'#*+!*(%'!%$)%*$!!!))%*#!&$!'#(!))#)"$&$$%'"!*'!*('#$$+"+'%'#'+"+!$"(%*#(#''$"!&$#*('*&#*%&$%)'(+#$$"$#&$&
@r9459
TNTTANACNCAGNNNCTNCCTTAATCAGCATCTCCTGCGCGGTA
+
(#('$$'&'"*&##)'$"+("(((#&#((!()!%&*$&*+%(#'
@r9460
AGGACCCTGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGAC
+
''"()*'!#+&%%#''++&+("$#'+)+)!&*$*""%#)))+"$((#+!"*(&!&%
@r9461
GAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATAGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCNGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACANCGCCATCAG
+
,&&FE548$CC7!#:1*0*+G?AD??&($8/?#?83@;;/>AB;6$>6/:#%9=39E#;/3<@A25CCFH:G%C#:D-65@B<&>7>,(FG/D3(6$!<&*9<A'F9.,,157<*,%2@%*.!30+@.9"@F%HC<.B)>.4,.5A(;2B/''G+=!-+GA)./)C3F4-).:D"E*!#
@r9462
TGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTATCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCG
+
>)H:*()>*<&1+2&#G4;A9<<&-9,H)H)HF!&8&5,-0+>E-+A9$;&3959%D77-$D;.<'$!->#=7'5,.;=:9H97F#:91C0&3D%D='/(-E3%<5;43)=GB+)=G)(F5G)F8358DF)=7".H>>56'.;0>*'F(-0#E+B2&01C#F";.7>')>H=95'7#&0:0<A"&+B99EFBA=B"-+?3D2D&(+A&>$D)(;5=*!$GG10(4BC+G$3:
@r9463
TNGTTCGGGCNCTGCCCNGAGCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACC
+
$"$*$'%'""!$(*!#&!**%)%("+%%($*++''!"#!+*!%#()&!#''*!$)&'*!'#'((*+#)*%*+&+""")$(!
@r9464
GTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGA
+
E-"3#%(#55$1B:=,53:)$35<!$/)//'@(-*+:**4))D#HG4B<E5(7&BD/8$/
@r9465
TGGTCCACAGCCACCCCGGTGGTCTGCCCTNGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAG
+
.+&F%;<&C3$-/D4(15E52;8;#H#0=!<>8345>"DD>"?17DC;D#4''6!9#5+(AH1E686
@r9466
NCAGNCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTTCGCTACGGCAAATGTCATCGACGTTTTNATCCAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCANACAGAATATGAAGCCCGCTGCC
+
!+&'!#)%()+"'"!("(!&)(%+$")!*++!+*+#!('#%!((+(*(+#+(+*"'%+$)"*+(%+'#+(!&+$*&(#(&)'()"!$*!##*+&%&+#!#"!(+*&+&"&#$$$(&!%!!#%!)&+"%&(")'(!!#*)*(')'+)*#"$'+(')%'*+$((&''"*)$+"#**#$!#"#+*+*"$!%%)&*"&&$"""((+"("(%)#"(*!('(++**&"('((+#%&(
@r9467
GTGCTATCAGTTTTTATGNTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGANGCAGGGAAGCACTTGAGTG
+
+&&)"#!+!#&+*"'%)!*$*%$'%(#*#$!('#*%("+#+!)%+$'$%(!+%*#!!%+*+&#'%#&+!#!$))$*))!!)!$"&&&$(#!&(&(*&*)&*#(&*)&+!+('%"'++''%+)("'!(%!*
@r9468
AAAGNCACCGTGTCGGTCAGTGGTATGNCCATCACCGTGAACGGCGTTGCTGCAG
+
7?=*8(F(:G$?*>4C0$7+?F@B$=))?'$>504';HH</0;F!)D5(E+3(.!
@r9469
AGGTGAGTATGTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTNTTGTAAAAGATAACGCTTGTGAANATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACC
+
:%338>&%04$*":C;;H$%!()9@AH:E!)97,/9EA842,4D#>2"9H+F?<$%H8BD%>#%0!225H89*'-!5#:0D#@2<-"6'#<10,/9A'42<#+)5,.@-D-**>C12E:<D4".9'%;>'HHHA=&0%=>+AD&A%>
@r9470
NCNTANCCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGGNGCTATTAGAGCTTATACAGGCATTCGG
+
!##%)+'%%+"(*$%&')(+)#'*'"&'%$%!*'$#%)+$''($)%$#&&*)%$%"'!*')%"%++!")'%!)"'(($))*+%*"$&"%)$$'$$'&(%($(
@r9471
GATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACCAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATNCCCCTCAGTGTCCAGCACCGGCGTACTGTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATNGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCNGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGNGCAACCATGT
+
>??%E#1/$+804@C;(/?&-%BD<F*EH+2B(E.B8;5B'D#.?B>1@0(#&57+;4<4";/*',#0F$E=F&',A64:;";"41823$-,6BB%&.5=7!F>2/CD;00+);6>21;>'B,"?53)>@B0.@FA6/12'-$+DF40@H14'%A04+8G2,0(D<.3>.*9&6&0,/!':G0&<C"C@->%4F!AFD$@<<?1C7/CD9D$F)5+.E?$>5<2+<(FA8!?C$)G8*=!%0D>D0C&EA9E4AB>;7F8%"0F>$-'0B,A)#*&&HAA-:&!9C(BDE3A-.7*,,D)'+87+:22;85>6-13&'B%6.A431=8!H0.E*E0%=DED'D.!G)4E-@$D=$;)>>,(+0C$;.A4?@A%>?9=@..3>4'3A6D3',)8@HD.H.*C-A0)'8FF@E6*48AE(:&86='?=&,*9.3=3';A#)E<*#G4?4>'79=1168-;CE12DH0-/>=!4.7G91./$1</&A2658G83
@r9472
CCGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCA
+
!?C2@,7F,;#$.'G/)-6:+;&('-%1")&",.C'?!,*7E(37E6AB*5!8&/<
@r9473
TGGTATTTGCTGCCATCAATTTTTTCNTAATAGCGCATCTCTTTCAC
+
$/5D"@@+F<<F6)#C/".*9(,';$AA,E2,E"/7BH&%/584?HH
@r9474
TGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGC
+
@/'G*$/1(.;E4,2*"4*#B=A09$5E?%F1A:52'=C5:C+1)73$6
@r9475
NTGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCACTCTCTGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTT
+
"@,6,38:-9?G);,C89)4)0-?A69(C;(1+464.(,'H63=EG"*@3#:C.1CD'G?D!9'@*)@(;,7!!51A'56!*194/<9B5%??/D"*>.27'%)"$50$-%!*?>7?=%F";"2@F?E%"?-F"<"18HE4E:@%0A?F
@r9476
TCTGACGTTAGTCTCCGACGGCAGGCTTCAATGANCCAGGCTGAGAAATTCCCGGACCCT
+
%4"D76H&";"18:>:,0H5H0!>!6!<9H56@$#8C0A#/#A8?<6>4!':CA)'=!!9
@r9477
TTNANTNAATCAATTGGATGGAATTGTTTATCATGAAAAATTAATGTTTGAATGTGATAACCGTCCTNTAAAAAAGTCGTTTCTGCAAGCNTGGCTGTATAGTCAACTAACTCTNCTGTCGAAGTGATATTTTTAGGCN
+
(#)'!%(+*&#&(#+)'+$+!*()!$)('$+'$&$$&)#*+(*(&(**)($#&&'+!"))%))"++$+*)(*(+$$*)"#*)*%%(+)#&(!"+$#!('$"#'+%!$)"$)(+"!!*+$(''!$*"&&#'&*)$'%!"#
@r9478
TANGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGGTGCCGCCAAANAAATTGCGGTTATTTTAATAA
+
',,:3C=9$8@:;G=?(0-:=,@>?7209GF.7-<>C:2-.?9%!=+@A("-49)(8"=.G*==<F)9!34%4=26%'"%97#')*':"B"B=3=:+2?GC0?05
@r9479
TAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAA
+
<$*=CA#F@D(ED6*5>1,B==&',&?"&/>!%%D@H@54C4/E;"C514?1H#"-AG)@6)'5%H=#C5:&
@r9480
NACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGG
+
&G/3;7,5-!$8>.+2$8%-=F>A&,6AH9@,-<%C06EA/40%5H#538;>G=@"8C$D2@@"=:77/9&D"4E!:H;#$&'"D#<&C?<
@r9481
NNNNTAANNTNANNNTGTCNNGNANANNANNANCCNNCCNNTCGC
+
!!#"$"!!!"$""#!#!$#""!!!!#""""$$#"$"!#$#$$"!#
@r9482
TTGATNAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTA
+
&&&'%"+!)%++&*!"%)+$""'+"'*+*&!*&$!&*)&&&)%#"(()#&*!"')($'*!'
@r9483
ACATACATCTGTCGGTTGTATTTCCCTCCNGAATGCCAGCAGGACCGC
+
;7"/*!5'4A*C:61;G>E.!61/90)/4)42=2*FF&&F53121C8)
@r9484
ATCCANCNNAGGCATNNNNANNTNCTCNNANNNNNNTTAGCGGTACNTNNNNTNANNACCGNACNNTCNANNCGNNGCNNNNANNGNNNTNTNGANCNTATNNNNTATANCGAGGNANGCTTGNNANNCNNCGCCCATNNGNTCTNTNNNATANGGNNTAANNNNNNNTTCTCNGGTNCNANTATACTNNNNNNNTNCGNANNTTNGNCTNNATNGNTGNATCNCCANCACAGNANNACNTNANNNNTGNNTCNGNNNTCNANTNGNAGAACTGGC
+
"""!!!!!#!#!$##"$"#"$##""#$"!$$$!!!$!$""#$$#!!$!!"!$$###$#!$$#$$$!"$"$"#""$!"#""!$#!"$!!!$""#$""!"!$##!"#"$$!!$##$!!##!!#"$!!$"!$""!##"!#"#!!#$##""#!!""$$##$!#$!!"!#!!!#!$#!!$$""#"####!$##"$#$$!!$"#$"#"##"!!"$##"#$!##$"!""#"#!$#$$$$###!#$#"!"$"""!""!"#"#$$##""!"$"$$!$!$$$###"
@r9485
CACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAAGAATCNAAGAGCTTTTGACTGCTACGGCCTGTGTCNCTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATNAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTNTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGANACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGG
+
,*,%37E0%1F="5&:$6?2-48E8-%BA4G1(!6;.A"+9F-D>>;+;4)"618+AE8AAD3.GA@A@=?-:-?62A6;-F<9?!201A>?9G7)/'@;<AF614".=7,'7HH1:7+$9:=$75-53,%0-+3>1.9H5#ED==6-69+!,'A8=B?69>D2("&2&$2,*=%84,"E=0#'H.(G938BG3#;@,:7+E:85.;*01B!%8905@;;"!6.83-&<&5;@9?=$1E3E#%>3#->>;,?#5"='!4F2F.@D9<.)H>5@5F+GE7@.E$,G59>9//@2<#G/H'EGC10H<D'+-7A9()4,"19C$.*!G)7$@'E27$*5C=(!@:?'B=6F'8,<G()<,1B$28:=7H"146@=/7,A;3(2/>DE,B=95H
@r9486
NGCCGTGCNATAANNTNNCCGCNGANCNGATTGCGTATGTTGCTTANTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAG
+
$**"(')(()%)##$(*!'$(%"%'!&!'%(+&"(*%$)*%)%$)($$#$'$*!(!)"')#!!#!)&""$%+""((!('+'+(
@r9487
CTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCA
+
0'&:2079("@A,;724A#H$3"/)$?%;/',EG?063=/+A#;BA&*EA0
@r9488
GTGAGATCGNTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAA
+
@C;,1-!12&%->EF2)2G*390A5(B.-H7%H*0H4F=2>'&9
@r9489
CAGTTTGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTC
+
,F33/:5C(=6:E2<&A6!>:#5"2"7(8$*H%?7.!)EB@)E3,7;G)2(8'D'*6)="(@G7=3DD;?06/A;7:$H
@r9490
TCNACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTA
+
64/.FE)$.'<B+9(#-,=D07"1&C*HC844A@!!7B4/(;7>0(:@7.E+7;
@r9491
NNGAATTACAGCGACACANCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGGTG
+
!+)#*&)+"*""*(($+)+"#"'"$!%()%""&%($%&&+#*$'(#(&&%#&))$"(+&#)**))%!#$"+
@r9492
CTCAGGTTGCCATTTTTANAGAAATATTCGATCAAGTGCGAAAAGATTTAGTCTGTGAATTGTTTTATTCTGAACTAAAACG
+
:(2<<>-0=4'7+;!2"7<.&?A'+.9$<19?#@C5H4&6;<:(9(G9>,#A;:3G7':0:(0D*',>*9)4628/$++'8$
@r9493
CACGCTGACCATCGGTGAGGAAAATNTCTNGGTAGATCGGGTTTCGCCGAATGGTGGCGGAAGTTGTCATCTCTGGCTTGGACGGGG
+
%'51(G+951!&*,@661A&&A"-#A8!4,67'7G*7&F'$&641D61/,"&FB44F!>DC3%A9+;%=889(*&089;F%-83)7,
@r9494
GTGATCCGGTTCTCCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTCACCAGGCTCGCCGACTCTTNACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAATAATCCCGAAACCGTTATGCNGGCTCTANCTAT
+
6F2+;+E9:)5"C?*C0$(=8<CD&4.'<+BCF,!E'?"?H-0:(#("5D6"@B71<F,&8-D.C4):#;+,*"13>.'G'"839-<?/8*$B4G7*-GC'->?*=9A)-"/G:<-G8A;-<$1>G</H2+"3(A&8F:#3=;=F<B3#GAB>=4$
@r9495
CNCAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATNTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCG
+
"$+!""++#(&")&%!+!("("#')%#"#)*$$+#""'*'*&##&"")'%$)'+%""%$)%!'+$*(%!()+!$#*%&+)!%
@r9496
CTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATGTCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAAT
+
AA4*.0)!32>>$>.162G"&GFC-56%D9D9@(A:1(;7:5B*')<7H&"+1:)7850F<H,'3F,1'+//@-F&E8B0.*C%>8E&(*%%F41)>E"$B,@*+A7D7C!#7",>&5;<%EH%$6<#G5<%3/E0)*6B6G*/6,'@%*#ED%7CFH=19#>F>,5>?>43F!$/F,<-90E&E@5!$&#6*>3EH=@A'<471$(@$A6!*#D
@r9497
CGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGNGGCTGATTGTTGTGACGCTGCA
+
:)C%08@E3.H?G'4'/.065%&59<A':)29,:<&,!.%=$&H'<7@F<F8$-+
@r9498
TCNNGNGNTCTTCCCTCCGAACAGGNCGATATTGTAAGTTCANTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGATAGACTTCGTGTTGGCTCTGTCNC
+
)($!*''#&)++$)&!*"&%!''"$(&#($'(%(*!!&!(*%"()%"$)"))$)'*#$#&*()*%*&!&#''*!%")%##&&()&$')"#$)#!)*#"+$!)#&&&#!"#%#!$('#)("##$!#
@r9499
GTGAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGNGTATCCTGGCTGGATGCCGCAAAACTGGAC
+
A7!6%H5*+.#+A.'?8B>),%4?E*>H/&<*(3%=61$=B:D,DA@<6C15,1%(6*(*&'@;4'?5/+<7?*<A3:E!%3'H&H2C8;9$E,01/.+FAF26@B<7'?98G77H7G#G!##DB7,.3?C:1@<09"02G'HB'%
@r9500
CTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCCAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGNTTTTCTCNACTATNAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCAT
+
&G-$./C+*8(C=+:1?"%F.G,G2C*>-EABG+=-AAD0A/C>95A<<5@9-7+2$")8!H873FG2>'/@1!9C=C./*9&H<7'>H@>./(!"9H/*=';0H&?1300>'48F,*+#A;.E87F!CD7&/27A=A2D)3A:023>;0-@6;$+D'3G+--,"FB3)H(8;*@%0C%&F
@r9501
ATAGGATATGACNTTTGNTATAACAATAATGTTATTGAAAAATGG
+
E;8$0$D6*%6-1*BF&+)=%?".,F6F-=@.</*3.5C/6H?A5
@r9502
AGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCGTGGTGTTTCTTTTTCAGCTCATAGAGATGGTATTGGGGCGACA
+
$H81BF<<$@!>6>=H!2B-!7B1A5=.*'B7;90@13,45;CG(C8:EB!+>F7:,&0C>=35G*(?/G?F*D30B:?0*>=%;G(1875>1E6F)&C(;.*0)!).A$@(7<?39*#8,/+$H&)7%$)"'CCA307?*.+FB''@A8-)CE@?%E%$+>;
@r9503
ACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAG
+
:-E=82C!H3(4$B6/,--"56@('E)13@?1=70<=0"=3
@r9504
CCGTAAANTGATAATGATTATCATCTACANATCACAACGTGCGTGGAGGCCATCNAACCACGTCAAATAATCAATTATNACGCAGG
+
35:0'-76**<$,"C<29.-?9/>2,7@(DFEG$%F8-@0,B71<H(@$H"$)G-(5!F0$5+#+HH(#:52@&GD426@7BC19D
@r9505
NATGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATG
+
$"@1$2A83H=9G1C*;9,$C>77/3-E$"0)8E#94>FD!59F.8+%G'?@@*
@r9506
CCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGNCTGCGTGGCTGCACTTTTTACCTNCGACATACTGTCCGTGGCGCTCTCTTCCCACNCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAG
+
?=G;=(&0B'?H7$F%B>$E2/>,<38C:A1+:<69-;.&B)+(D!)<5/HEF"-2'D%=94B>45*3*=6"=FDEF83./'"=2H'HA31?93;62"-..%ABE%)AE:6G1;F-(+>G4>8-$4;:!,-1"C8<=;3-B6!
@r9507
TAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGNTGTTTACAT
+
E;5!-G:;>$E./7B"-/.@'6'-'G1!!=#H16*A@,$>)>AB@!+;2?
@r9508
TGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCT
+
&+$'%$"%%)$'!(!*#*"*%&$#+('*'*%))%#$+)#$"$"*')#+(+*)*$(&''**%')'#)$&'&((*"&+!#&#
@r9509
ATCCTCCCCGGTCATCACTGTGCTGNTCTTTTTCGACCCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTNCTTCACGTTAATCCCTTTCAGATGACTCA
+
5/!@B1"3!BAH/'<%B;-+:CD*%10.<D/8=;'6DE@1931"B8&*E+#@4157@,5!AF4'/A!B)7;;G$3'76*=2&+3&><750*4:"E+C9G*=0H;-*/%%.$<=&3E)G2@?#
@r9510
ATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACC
+
+.G@,7$,9'/E@,<#$'.*4/&*:3*%2?"-G0!H6=D;>'E=73@:'>'E?8
@r9511
NGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGNAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCNGAACATGCGTGACGAAGAGC
+
#C($:F)'A66!#2%22,%12CH+&3<'H2.A/*)!*(@)')>&,;#G$=::5A8$:+5/.1,H;-?*:9D;-01#E,!H5/@95?:2?G2@)/3"?6%8E!78B5"',<2<;23%+(B1&/C@%))C8B'8(HF(-<&<-H:#1<56<>*:@C3,,*)C7A&-.
@r9512
TGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGT
+
/326+E%#2B&B8:G#<EC)4"*)'$!D,A<9C1A:E8,96"0B>%$4"$0B9-AH"F8'B4
@r9513
TGGCGCAGCAGGCGGNTAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGA
+
5G8%G.<3*)(B-:DF.-$@6=EH/*/&G/:#02"(/"<)/'01F*,D2&'0!EBD1<
@r9514
GACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCT
+
26B+0E55"D9#&D3'@(-01#;A+1%1BHF@D3030&5:-3-**=&#,6
@r9515
CNTTGNGNCTAAGTGCGATTCCGGATTAGCNGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAANTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACATC
+
)"*#&#%)!+#!+$!#"%"))")%%)''$&""($+)&+!'$%&'(!*$'$+%)####+'%)&$(+&+)*!%)&#*'"*''&$!'%&((+!(##()')"&)#)+(+"()#$&()!!&%)%!"$%&#+%")$!+"(%$(*+)(%%+
@r9516
CGCAACCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTG
+
*@:,<$9'.'%D07770,*@,2/9=27C*")8'.<G68%&53)H'74.'$(H-6@
@r9517
GTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTCGCAGCTANTCCGGAATCGCACTTACGGCCAATGCTTC
+
0,@4;5%<"D"E!0--8D@1===0-1%4(/10<3:+#+97'",@,5G)5(@52?2%/3'%?)&>'(F"81BG+!%&2)FG2B4&
@r9518
CCTCAAAGGGTGACAGGAAACGTCAAGGCAGCAATCAGGATTGCAATCATG
+
8H.'H,=:'5H%#B/B9#,'AC3%63F8H(9(5>=!3&C6G>B0-;+80=,
@r9519
GCGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCGGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCATGTTTTGGGTAGGCTGATTTGTAAAAC
+
"B%"#<&)8&8"+F4=F%.C0>*@6=&G.&4')(*H9=1EDC//?9.;*3D,?.,+:*DG#!<)B51+&@1%)HH5A/6..#+5,$$+G0;$78&;0A/-F71!DH,B016E/<B'9+-&@<18-):.):8'75@G#@CE!D$D1=<4/#4A4AF><6*@E7/A06B8++$0E2>9774H<%."#(?>8<%<.<$6"
@r9520
CTNNCCCCACGCACCTGGTCACGCACTGTNAAGCCCCTGTATGACGCTCTGGTGGTGCAGTGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCTGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTAGTGGTAGTGAGATGAAAAGAGG
+
#'%#(%&$&&&*+'))"(+$'$'!(%#$*')#!%#)(++")!"'$""*#%&(+&!%+%$"$(*((&+#&*('(##&"$#"&#%+#%$"!+!*'%%#+#)#&!'($(!(!"&'#)"*%&&+"'"+&+&%%$*$)(%%"%"'*%"*$'#'&"$%$#&$$&'(%%%'!('""#$'#("%#%%("+*)($%&'+'*($(*&)'+$%#$*&**#+&$('$"'"(#"$%$%(+*+&&"*"%$
@r9521
AATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTAC
+
F8E*)$1;7B<)E1<7@AF#-F:1/H*)'$;9#8E*5=D(+B&G&6D
@r9522
CACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTG
+
4;FH6(9$#&H=0>-C(A<B6:2A4F>A-%#'H-D+B>H9$H*9>:*!$>"<61,3'82*&86-H#8-@0@B$B9D98E6(#F3<.#,;9.CBH,:(;=9."F<?FF<2'%1
@r9523
AGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGG
+
9+3F:>7'?/#2,0=1<A@>F#5.#2?;)89@&9"G46-(D=%*CFD=27"@/G3$5!9+B+#(<5*<C1F)1%AD*9F;F26E(2')+
@r9524
NNGNTGNNNGANAACANTTATCNGCNNANNNCCGTCNGCTNCCTNCNNTCGTANNNNNNNCGATNTCNTANNGCNTG
+
$$$"##$!"#$!!$$$$$##"$!!#"!#"!!$#"$$$"#$$!""##"$!"$#"!!"!"!#"$#""$"$$$!!"!#!"
@r9525
NGTGTGGCAGCCGAAATGACANAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGCTGCCATTGCTCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCC
+
$;<5:5A;E9?CC*24#;&)B>F4HH?'"3+,A-151?,:<6>+-@!F5*1>;EB/.$:D#E8<E*"(.32!3$D98.;B>#$&(*/3:,F=#C97B(6+.?711=4./H;-E;>G7,'A.<03;H43=+E@1:<"0#:&
@r9526
TCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTNCATANGTGTTAACTTCCGCTCCTCGC
+
,)5:7E"36(;',%-+G*4&*;>47#;1@>/;0>95$99C'0FA%-?2C'-+82F:3/AB#9'&9/4,>'7;2B:/?$41@='E0?*/4>?74183>$H=1>9(#3E,;F:G8?@
@r9527
TTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTNTTCCTGCTGN
+
D="<@G)08*D$A-?D+%.(?99FB61>H6&*4A8)"D!F,!7<;7"?@350ED=0:
@r9528
TACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAA
+
-8+0=*>9CGC2*>+5>&1/3533*1?0-D'6%*?H+6A&6.%
@r9529
TGCTGGTCTTGAATGGGGGGTCGTTGACGACGTCATGGNTCGATTGGCGCGACAAGTTGCTGAGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGNAGTTCTGAG
+
&@#70$#)'+&EH'$D#3(++7H41?%==.6G717>BD49**$/D3?=?24'G$+F$7/!C:B"B#<C3'/BF5E":.5)"D..($4-@>D*+=8D'+G+=*E5AE.#,7GB(HF&>B-0.'F8)?*)>9$
@r9530
CTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCANCGACATTCTTCCTCGGTACATNATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCCCATCTTGGCAGGCAAGTCCGATTTTTTGCGTTGATTTTGTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAA
+
1!B++*?=!&HD8*=$8B05)+FBC-2#$'$CG4>B+$D!HC7.=#13"8)0&%C33D69,-!=C<@6&08BG@2HEH5.>$;:?9H5<.,HAD*D#H@H*'.6ABA5>-C-38=A8(.H1679:G<@,16G=?98<E0A<%6,F"'F$6,1-)H8,:8@;D93*7D2:>/9-0#8&A2*,);5A(41F288289-CH+"(?*:B>(@/;!94(C5AD2704C6;7==+0<-*)>
@r9531
TNCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAA
+
%)+)'('#+&"%)!!!$*()'(%#(%%+*()$!&(!"#(!$(#''&)'*'*%+"#'#
@r9532
NGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCT
+
%5A5>@4<>F)$&68.<=)%8EB'$/A:;=1?B$'C@25>F"0@<
@r9533
TAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGTACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGNTA
+
7,'*+?<=0!%F81($C7//E*;$&=)A2!%+;:!(C%D/:=+-2D**=@-6DH+C7>:@1G)/E-59!*F'98@+B"8;?76E%F90"-C0H2,"/*.=4H:6<=<"";E2@,A=!&05$CEE,;
@r9534
AGCAATCCCCCAATTTGAGGNATGTTTTATCCCTCGTTTTAGGGGATTTTCNCTCGTTTTGAGGGATGCACCATTC
+
<$D+<F%8F5C@/7%E.7@%.#?%A09"=6,78'*)H(&H=3C:&*5%4A"*'>9G@*1;*0:+4-C#(#//.AH+
@r9535
GCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAAGTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGC
+
HG$'+5&D-H)38#6%-42G?*%6:8C!C)A8A20&8;31;-)&-A',6-.#"#3**1.9-#C9:1?G@-G+)8.+*F*"&?#AG*<<?<?9#G>'3D+-):#H946,8%9;"17FHA?*%%849A52;/H.B<>#2D&;67
@r9536
NCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGAAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCC
+
!9,E>!9;C$E%>#=.>G?"1D/+@A61@A68";G7%C,G>#%45,4519%466.%/.8H60.<?4B+E-$H!*B+#0(>94!(2H'62?2;5$;A=/:B?G@%B"H*B=7A=3
@r9537
CATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTAC
+
@559-C$F9*+65;<;7':;ED<E!"(&"&?9&BC.%',"+4D+65160C1!H.F:D-G**/,8"+%CF&A0BH:0/5;D0H,'G%
@r9538
ATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAAT
+
<G"%0D>7G:#'>80-7?3,+G4@110/F."7(4EG@@43C1@9/2)/2!/E)"#B?/A*!-;/76B7H:.>#$
@r9539
GCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTATATCGGGTTTCGCCGAATGATGGCGGAAGTTGTNATCTCTCGCTTGGACGGGGCGTACCGNCTGCCGTTAACCGTCGCCGCT
+
0E96);95.5>9#"%H95HA2E3E51-$6%&C0%)=G<?)E?>=%+'>*,*3,=A';4F#4@HC<D%#1/G(6;):C5GA6E%7H%'?H%F3)3A.(1$++"(C7:<(=EG,B*G$=!7:7%)1#%12
@r9540
CAGCTATGCCGGACAGGNCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGNTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGA
+
E,G-;(>35-GB=D;C940;=$E6,-!9.:H3!05D=?8HG40?C';:6/81BE$AA#850CGF(9>%(+!?1*3@&27+/'+-@&6EC#B936'$$16;;-.B3C(B
@r9541
AGAAAATGATCTATANTTTTTGTCTGTCCGATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGNCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTT
+
+0$FA4*1+3&H-"G=H'#)B0;)+B+<D!-,GG"5(H.A=..16H"0+*C78G(&&47A,B633*(/#'/3$-)B+@9%23A(;!E?:?'5H/9,51(F>.H(HE?E&;HB')@.;.D!27&H
@r9542
ANNTTGCGGTTATTTTAATATAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTNCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTNATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAATATGGTTTTATAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAANTCCCTG
+
(!%&)+&+'''$!+##)%*#'+)*+*))*""!$"!'$("%$#!$&!*%#**(((%!'!&*$!'"%#+#'!'"')#%))')#+#&'!!)#+)'$&&!%&'(*+!($)$"'!$++(#&!#(*!)#*''"%"*&'+)$'+%$&++"'(#!+'++%(#&)))$+'#%$*!('#*)%*###($%"+#$+*&))&+##$'!%%#$($*&&$$#"%)&%')+)%+"&'")""'*&)((!&*%&$'()*%*$)%&$#!"#+*)""'!$(++'&*'(%%$'&$#
@r9543
TTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGNAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAAT
+
+0#6!"4/'B:?/0FD#1"H)>H.DE"8C3C)$%D7C""A51.?+8%%@?0G2,E%<1-)D=4D!5">9:@604$;E"D:9>//*FH3(-=;1,7&:H9"+03<#;E;#!7)GC<+H:#)7H'<;:<A&>6,6='55D2#CD&F4<$;$*C@#G;50!7(B>$:.B0:@?44<GH06
@r9544
CTGGAATGTGTAAGAGCGGGGTTGCATGATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGG
+
,3/;HHB'4>9@"+'&!H+5!<:4D';A=9$!#DFE:6-*8'46FE@&-9A!@:548AB4'/A
@r9545
TCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGT
+
EG2DA$H36(&(5.,>>C1!E3**C7,.E1#':6D#G;%@$'>1G..-H3'+EF79H/9H4D#)"!?:'8.
@r9546
NAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAG
+
&H74A8&$%2.9/;1!5;73!92&)C-/H''6;)7+3!>!E5F;78233:(14&A22$B37($)03*3!:&D-#1>06!4/@5(/*((<!69#
@r9547
CCATCACTTCAGCATCCGGACGTTCGCCAATTTTCGCCTCCGACGTCTCACCGAGNGTGGTGTTTACGAAGGTTTTACGNT
+
@G1@5??&2>$2/(.G6;$$:/%)//;B.74=-)*C>"$*,=6',)?D-189G2.$#>C@C*<G&!:AB)+*:'$/D+"65
@r9548
NATTTCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGGCCAGAGAAC
+
"B?H/+&8)C0@<H<F&./29A.#)C9H9<!C"(8&2#">"D/@<E/4$=549'G,-*G*1;#D=+C5
@r9549
GGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTA
+
6-<E*+$@E"(:@E5:6+@=7=1D;=%40.(7"<593:<D+F'2"$1@&,1E;+/3B7E0F*G9
@r9550
TGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTTCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTAC
+
'B:+-2617=.,&G.B/45?&$#&%?;2#H?#E@E?!0A':=8BCD(G?=).?)DDE08D@"D+(8"B6A?5@*C2)/-+?A-57;E<()C%!0"6:5D.1%>$4)(3A,?,!="';"=.>A4&'#H16'+'H41!5H9;F0$G7$5G675B143)B>3<38+/@339/,%<'
@r9551
GATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGNATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCAACCGTCGGATAAGACGTGGACNTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCTTGNTGA
+
6<$F4.A).F%4F@*-=24+DG<4$7@)6*;$+&B7>'/.)(9;*;8/6&?=E5$<B=%,.F=@47..->%/)828D(A-:4C3/'.2?.5"7A&!G"#;)2>AA80844?+B:F@.*<9$$:B;6$F3(+B$&@=A'6!8!4/3,2B0=<=>-*,561H5>""5..F=,HF6(AG28/'G194?517)#3.=>%E1(!.*9#'.+A28&/#4$GBB#,).A'510#8#(*1C01*1?/A1:4?D
@r9552
AGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGC
+
;83H-:-:0C%375*;G+$-4#18,HA/"3G0D=@EBD?68<9HA:/>0GAE5:=:0.29=@&:<H08,.0E77&,5&,(G
@r9553
TTCAAACAGGGTTCTGGCGTCGTTCTNGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGG
+
<052A:3=?%/CF2'?77#FEF*8/+.H/:;E1(!*:C,&C'@C",9)84&3"2@:==4)H=F59$+'2F<'>!A5034(1/&7G$!G""#A#7:&;7@EH
@r9554
CTGTGCGGCTTTTTTTACGGGATTTTTTTATGTCGATGTACACAACCGCCCAANTGCTGNCG
+
+$&'(&%))'*!'#*'!+''"&%($(+))#$%$)'%#'"+"'#%*$*)&"*)$$+&(("$'#
@r9555
ACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTANCTCCATATACCGCCAATACCCGTTTCATCACGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAG
+
*7*+*=368-3!97A140%?>?2D+$AB*1D0:1;3)0/DG78,D.5:--30>4&>GF)5!;:<>G4#%;2C2>%-=$12?E*-/18+:7HA"936H>2@>*?;&3,8)'.'=E>"3,59-'.H@%,D@H63=G(,>(1-2)C?2%A=G!
@r9556
TNGNNAAANGACCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGTTGAGNTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTA
+
%"("%#!"!*+(!&'*!!$*'!!++*$'+("*'!'$!''"$""((+"*(+%'%#")&$$)&*)*"$+!**%&*#'")#'"!(#'$+!$&($!#"*"(!#()!&#&")%)$(&"$&%*($%#+&'&)$%#'"%)%(#&')!"%&#*%$)+#%$$"+*)$&%($'!*$$#+$%*+')!&%)+(+%)''#!#&!&*#($+())&&*%#+$
@r9557
CANATNGAANAGNTTTCAANNNANNAGANNNACANCGNNAGANNAGNATANTTNCTNGNGAANNTNNGNANNANNANNNAGNNNAAAANGCTNNACANCNNCANNNT
+
"##$!""#"!!####!"#$##$!!"$$!$#$$!##$#"#$$$"!$"#"$#$"#$""""!$$$#!$"$#!!#"$"""!##"!!!"#!#$"#"#"!#"#!$#!#$$$"#
@r9558
TAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTT
+
@/H.*5D.G%2D##50A3$:#:18&)<3H@7+/G1.6E9+5#3%-=.,E'"GG7A%3E<>+'=4?(+":/=)D#.,D#B/8+1!3%D-3%
@r9559
TGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGA
+
9A1@472=*3&-"816E=3@"BD(1.F,!2#=E+!$6D8*A8''#+8G5)'8/2;(8#A>15<',</8E%B><,60B<%9659;85DDDE'--A,4B,6>$DA4+*B#8?=:HE0?"2""8:%)-*>((/-1?H-C4?:F;9)1.@;@
@r9560
TTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGA
+
/>(,0>&=B.<2!$";6:#HAH/(#?H&("%6,G091(48A8G=$9090>7=++;$((!=1"4;#::<CA+$=G5!,2FH+7);B55/*.;1F#,#$?/:/16.C
@r9561
TACGTTGTCCTGCCGCTGACAGTACGCTTACTTCCGCGAAACGTCAGCGGAAGCACGACTATCTGGCCATCAAAAGGATGGTCATCGG
+
3,<=157)202F031,2"/F438&4:%<G$G.@F"7#B(/7G5+6"D=;@,A$:<0;&GG2)#H(0=62.88E@!;$?+*(B(5:%BB
@r9562
GATGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCG
+
%!9$F8F90*,8@+?!8&&7?F$%+76/&3-.57C<'EG.(36":3G#=;6,)(D<3;A2"9>1&2/8++3-
@r9563
GCAATAACGGGAGGCGCTGTGGCTGATTTCGATAACCTGTTCGATGC
+
6/A(/<)@1-B.CE!*5E!9#ED#;./*=63?77H94B5<9:#*A+,
@r9564
CTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTC
+
71?<E(H$@+'<<'?:(9&?@,C=DC).GC5#H',-"8A22>
@r9565
CATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGTNCGATATGGACACGCCC
+
=8!7:<FGCF3*&G*@,9-2!G0H+'*9*GDGA*0,)B)#6!@!.HG31!:;&<'4H@42A3/)#&=8#=,H?G%"?(3@E9>2<DA4=B,,1+<H@0>=5*HG$8:$!;E*.E'$2=39C/;;"5"A=,*&G25482<*0%.0F?>2A6)#&?>D,
@r9566
TGTCAGGTGGCTCAATCCCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGA
+
6.6..G2>>A<5D:C!A4G;6D);:G$<7E/F)A38G//$*5;<24!05.9:/)!28.2C(@?
@r9567
AAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACT
+
37@:!E/61$F;.7=)A9",9?*"'#9C0*12F'1+>!-*@G&*"+/BD
@r9568
NNNGCCNATGCGNGGTTCNNTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTNTCTG
+
$!$$%&($(%$##!((&"!+!$(""''("!+(%(%$#)%%)$'**$%*&*'%!!#)$%'
@r9569
ANTNGACCNTTGCAGCAATATCTGGGCTTCNCTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGG
+
"$#($+%$+&)&(!+'+)+("'+#!'!"&$%'&(%%$+%#)!'!'+!%!&%!%!+%%+)$*&+&)&#%''%!!$(!(('()&!#%%&(*+$(*+&"#%)#&)&
@r9570
CATTCCGGGTNGAAAACAACAGGCAGTTTCGATTACGGCA
+
%6/>52G<4F$-F!8@195#)1HC.$#C!.438@3':6)7
@r9571
GAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGNCNGGGGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTGACTGCTACGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCNTGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACC
+
E15>C/,$!-)8&A'+:$94669+()G"?"9H%<?70<A;7;'BC7<:GCH08"9/A2,!;0;,3*G/;B>7)'E&()%9=22>>(<H.9D4,(A#C:3!8<E7++@B03HC=,-&0/G:'+>4A"/F?A=<!#0B3!(4>8#*@11D.5B+?5--7;C>>=D$@%3+'DBC;=")"?&&+68*@)FA"FD:B'FFFH)-0C(*6@?F#B/:@F@;!D9!-;C&BH)></;;#FBH"!8&@&/B799>&(&5<&F"5->?=(<F%E62%'%6!@'7=-'C-DF6CG<3A"#'!'38D4E4
@r9572
GGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGG
+
9)-/*C'D>9"3GH3:7:H<G:"63/24B-&&91%*7;B84F,/9A!>%:5?>*@E@#4@G8F8:A$;*F$FB.%-0E+F!A#8C
@r9573
TCNGAGACAANATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCA
+
&&!&(%%%*)"'+($"+!('$$&+(&(**""*"%##"!&)$)%&!#&*%%))$!"
@r9574
CNTGCCCATAAANCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCNTTTGACGAATACGAGTTTGGAAAGCCAGTNGATCATCAGCAGGTAATCTGGAACCGCGAACGANTCANCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGTCACGTTCATCTTTGGTCATACGCCAGCAGTGAA
+
%&0!E':>(-5E47(@@D009+/CH637E!4F@FB.#8)&4@=+"/."@;6>()<6/@?;;&@,!!$>/D930D=%*>(#A6=%1;>,3&6C3;C?15HF14*9G5!D=4D))+?:;*>EA5E>(?E#;F2(20)!+680,8(3%5E:H&@%<?=&H..FFB813?1%9>E,=%=,&A<1<F$,2;FB#7%A9%!*.2>B-'*1E1*.@("+;$'7=H"5+?4>F,6H7#
@r9575
NTATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGANGGCCTCATCCACACGCAGCAGCGTCTG
+
"$8*C1F4F+3D3@7?;),,>2$1"@/<4DC@$,1#E+#&;"F>;65+4;38<$%426';?0?@'?+!:>D,F
@r9576
CTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCANAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATG
+
&9"8'$1"7..>">%2"7C7*2A,H6G:B>$-.&1&>/=:F@!A3!)5*>?60#0E?&&H,A/*?(->)-%(?+&C5>@4>;@+@,..'6?!./("4@3+!:C%3(8!'%9!FC-7@"5B)<%9CF)H-$G:;#3&G'<H;F=+$
@r9577
ATGTGCTCTGGCCGGAGGCTGNCAGCGACGAGACGAAAAAACGGACC
+
8%@06"@)42"+:F43+*A<)$FDC"C%",2!+F,#)0(&DD2?6>)
@r9578
GNNATNNGTTNGNGCNNATCGNGNNGNCNACNTANNGNNNACNNNTTNTNCNNANTA
+
!#"$"$!##$!$"$"$#""$$$##$$#""##"$"!"#!"#!$$!#""!$$$"$!"!$
@r9579
CAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTGAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGT
+
HFH%+AE;$(D260H?33=#&:A,C+.9;2)#(H:F+C?<:B6<9"F7.9.6E120H2434H8;?E!#H(CF3(+-F"2:C-4//E?;!+<4,'HF(/>C%2=/%(B65A>E*+61(H"F252H<18BDC*A2!>%'D!%<G0&A2455:&4H-F<3G*&C9&#</!%0;9H)-8=D;,F1G10'5A1&-8H;12)@?2!:;891$4803F"@39.
@r9580
GTTTGTTCATCCGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTNCGTAATAGCGCATCTCTTTCACTCC
+
$@-(3>8D<>#=$=%AHAC%?428>)'B.:H;-8,=1/H7%'@<F:D:?@E+"%/2A1&5C=(>".3%E/0,F(=*B!$0/G@)F1+61CB?%#4&>7;&@.-$C#
@r9581
GACCGGCTCACCTTTTTCGTTCTGCTCATTACAGAAAAAATAACGTTCTCCA
+
9"0?!#3.7?FD@(F92&-8#%$<;F:CA+<2G#"!:?G1'F'C&;.3?%3!
@r9582
CAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAACGGAAGTTCATCTGCTTTATGAGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCNACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCCATCAATCATCATTTACTCATGGTTTCCACGCACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAANGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAANC
+
D:&D0%,*486+GA7D<6'F?'A'76EF3F.G3(>?:+%EFH*G')>,#9!&FD,-C&6<"+H19H%BEC!B,$G3+HF#,A;&!%%A!78//@@6:9<.#6!G)H%EH9A*0-"-4!H>'F=,)=8*5,4AH+7++&-1(;G#!8/37E@(G:(+2)=.@=>F)3.#DG,+&.=?;'>+@=#11D6!1-H?!<C/&@%#8<=:D3%6G3(>(C41H=*DD271&,**E=4-E74@'B%&#(!6A;@"":2?:);?C@:.!38H8&)..=:A$E77>':>187G.%!H:B*(8H>D5B#*C;ABD)2,1&HC*1%**0+%@=+>*,$HC;<CE<.'7B!*9E
@r9583
GAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTAACTAACCGCAGAACGTTATTTCATACGACGTTTCTGCGGCATATCACAAAACGAGTACTCCATAACAG
+
2<3#83H5@H>''5(>>/A,"GEB)0EFAF"#./"6/G;>.*3'19&115H?@=''7->0H.G-:%-:7572<A%"/=E=>2#3/.2+ADG0D$4>"!!7EG:9B/,425C-=)&6!+,36@1&B!/()12C=&AB:9=<D9'4
@r9584
GTTCAGACGTATCCAGAATCACGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGNTCAGC
+
H#E@)=$G"=8H4>(,H<@6?'1&%9"%/D(96-=-"5"3@E.!*1C&6/B380%;9*;%4*@>C<*-
@r9585
GTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGGTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGNTACCACCACTTATTATNGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAA
+
092E%E<6-HD4!A($H0-'F12<E;%HGHA!*@3=@(=)#?(;@>A9'*=H7""HC2D:"/F!0-%!-''B',C$DF'<#%;G<&5;F5$>G?7-6F>#&90@GF1=E$8/4DF7#2G0*F@+.G7?B*/?&=9?=;/:4,!3?!4FGE?3$%>B62-HA0&3:(-E"5$GF-
@r9586
CCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTACTTAAGGTGATATAT
+
.CB"+.">*F-!:8/<@2+16+<8@7C;AA8+B>D;?<%"55">;(!3D+%7E41=!$@77F+=3>F);89$$,C).=-A"CF6"0,>9E(-6"*@8$*)&D;9-*%4/4;7#+6471A>2>7C0'!57A,61/74866G7/(,"&3-1:1A.,)G9F=&>#9&-0E$-*="9).7=,#%)*4;?57@-A
@r9587
TNNNNCCGNCCNNNNANTNNNCNNCNGGNTCAACNNNCCNTTNANCNTNGGCNNNTNTTANGNTCCAGTNGNATAAAATTGGTNNNNNNNANG
+
"##!"""$"!$$"#!#$"$$##!!"!!$"$"$##!"#$"!#$!#!#!#"!#$!!#"#$#$$!!#!$#$#$#"!"$##!$$"#"!"!#!!$$"#
@r9588
GNCATTTCTGCACCNTTCCGGCGGGTATAGGTTTTATTGATGNCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGTGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATA
+
(!=G,#6A).BE6#3;-@?)*:2H=@'2)EE'/'6+@*"0+$98<-1&/"!AB;.%4-D:%G%CH9G3.C+,G.F=$>BF8A<*5;04-!!1$1';5@-@6-F@-(?%F8A#)E/DE(C&H/D.50*C5&<"?B2164".>*
@r9589
NGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGA
+
#>D#@;2A7A+-8?7@=7%3!+"<G<7830+!FG<!5)>&B;/!:>0.:+!
@r9590
CAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTTTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTC
+
#<>?<5F*>'=.9/E7G7!=!)(HGEH82&*FG<<7:!&B88@%-/%94?F3:C:;@?<8<).<?--$B;;<:<385%#-:7'5+%
@r9591
CCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAA
+
2$5:,<.G("1?:H%D98%<3'?25?/?1D!-854/2B6E
@r9592
GCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCNCCATCTTGTCTGCGACAGATTCCTGG
+
E<5D&$);687;H<"5BDC;24/6)2G9/(*?0D'8&0!(=>:&EG%DD00@7*"9>50;DH7,7*'4DG8.!9903#?13A:4<1>;B#DH&;@@@6
@r9593
GGCCGGAGTGGCTCACAGTCGGNGGTCCGGCAGTACAATGGATTAC
+
=(?F;#E;#1"&/1@:$*#):30!7#70HF)%2A-9C./E7A@4G+
@r9594
CGGGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATNCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGAATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTCAACTATAAACGCTGATGGAAGC
+
-#"H(?C/00:H.@&0@?F>(22DE!'!AHG5.%+?%92&:;GA@"&5<124/,20H-#5,'GBFG4D=D@#HD6(8',*AF(#58B74HHF23D7,5".F02>$2024%<510F2&>0D:!AC(*1;GB;#&:72(;=&H;F63%-$F%G>=>/:-=,&499F:CEA%91'60@/$)G$*A)
@r9595
TCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGAC
+
HA/G>B:<B3';".H"F@3G@0AC,6.*==*<#F.6ABG6B
@r9596
AATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGATAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTNTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACC
+
,>8D;F>=-3CG1#;B861*<&3CHDA&2;52#'>>!3:/F!A)1E/(H6+5B"<D"-:;GCD8FDH$=EGH.34D;%D+1$CGC5%4%245G');9!;2C556#H8.*CF*3+*7?=A2&#45-;.#53)$1=B@/8/6.5D<,*,@53!%A
@r9597
CTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAA
+
G-"3%0E=G4*-#>;*!H;4G<1=;6-64H1G$('=%,<B#$D2$B8!*;G>E>2=/C2(95)'G74@#A,65.5GC2!>7>!DHF'/)&BB+,89EH.9!*E4A<
@r9598
GNTTCCGCCTAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGA
+
%!#=5(8+C12(7($E.A3/.A+(/;0@GG#@.1:;28;,(6;&B*+E#C&;9=?;&'8
@r9599
AGATAAGACTTTCTCCGTGGTGAAGGGATAGCTCCACACGGAAAAAGAGACGCNGAAACAGCGGATCAAACTTAAATTTCTGCTCATTTGCCGCCAGCAGTTGGGCGNTTGTGTACATCGACATAAAAAAATCCCGTAAAAAAAGNCGCACAGGCGGCCTTTAGTGATGAAGGNTAAAGTTAAACGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCCCTGGCAGCCT
+
?*)((:E9<=A3=4,(;/5G!0/96>5B."8GB:%F2:&<:%7;$F%:$0.*GB:3/*$%2754?!#(>&28D;7)%),E0<3'A:))("?,)H%0(22!&!/6)4!&C@;*>.*-<!+7D:A>%C$EH4+H9H:B-(2F@',$?-21,8,G?!:-2E))&*$<3*8(GD>E!E'&&:#6*>1&9(D"1-1:+?,5,8G9@;"$'/!?.&;&35",&AD>%@74:/",&3&%<#&?;,H4:3<>
@r9600
GTTAGCGCACGTTATAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATTCCACAGGTGAGCCGTGTAGTTGAAGGTTTNTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCNCACG
+
E#H#15;3$+*-!(H0,F?GA%FGF2@34C7-"'4,'C'1=?+;7;06G%+:8-6C>#=?;H+A&E+<#'G">(37E?C?,H<=-*"8+3:%3./B!D#':+,B:CF-#2?/<1F+86*5/0F#B*2621;54%&$4=%-2!:$@H')*G7(4'@@#7H-7G#,C2B.<#)$#)F$+:AA>9E)&267#7-@H06+6?@!;DE(<G<A71:((=&,1&#)@'@D9#5$3G,%"1#2$4E*5+E1$
@r9601
CGGCGCGGGCAATGGCAGCATCGAACAGGTTATCGAAATCAGNCACAGCGCCTCCCGTTA
+
>606=A!=<-D%0+3D1=-H.B?6'+$.H3;5##03F(@(D928!83<A?E':2,GE<C8
@r9602
CGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTNCTCCAGCGTCTCATCTTTATGCGCCAGCANGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCG
+
$3)6"6,&;G5:3%!+D'E#8(=E&<8*B%7C0:!/$BC7@;.@8'/+$50E/1"-14$3E*9<1*4G37=7:;DF;0?>1#H@@4'E+25<&2-2$F&"/8;A=%G387"3B3"295H,"<.*3&0'+*F@."2A,+E%>,+
@r9603
CGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCNTCGTGTATTTTGCATCGAGC
+
D<4)<+?G#+F+:<==F6%&E?4%@CB:17<2'3)?<C"';,);,H4+$E::=%?D*?(?*#!8+224H6$%-5@'44/%:
@r9604
NGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCAGCTTTGCAGGTAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGANTATGCAGTTACCGA
+
!5A@55:F:F<?$);#-8=%9*G82$:C,@),(:+)D(,=%2&F;<@<)@:@+$E+(B;G=8+GC.G5F6F=A/EC4H/13+'>A@(B::A)B)-8@7*1H.HF9D(-"+)H9-D
@r9605
GATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCANAGCACATCCTCATAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGC
+
/5$',@<6;:$F1,.;*,3!95F+-?@EB(#4-6$4.)%54#9F5DA5(C7:4D!</"<%2>*-G>:,*1'5(D17F/FG>B1<),@*76G?0;G;&E>)D@=132"D16#1*/.)($*-57"0D=</(H'H>2/-B<0>D8"G6C31(*
@r9606
TGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGNGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACNTTTTTGCAGAAAGAACA
+
..'8G-G2=='*?F+4!%GG2.63-%$>679"$4'?1$%<<&9?'>%)7C'<)/6,7,E4"30DFG@@.")+<D);B0/%&6;59=$F22/'A92/@G@/(*?<&.?;B0(?%FF=!;0F=#&'4%3?!!*7:H$G(7C/<*4.,"&<4+2,(<HC3>"
@r9607
GTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAA
+
-BC=%"53<#0./'+7'/G2208.9@A;HA037<=6:+0(E3+0%6B*!C((4F;:(B49%7"#=*.=,#2*5
@r9608
CAGGGCTTTCCACGGCGAAAAATAAAGTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACNGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAA
+
0'..'!+B#="6'-=/GHGE:)>155(*C62(-A)B55-)C!D6E?GA?&(AF?!6*&'0/D/.'??*/EHHH4F/?,-D9%=%D4G0*8/;.//,2&:+'
@r9609
CTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGNGGCGGCGCAGAAAATGTTGTTAAAACAG
+
*<-F25!'<8>HHB:'<4=!*1+%E3=#/:B!-:"3#%C?-32-)FD++79$A.+E5=D52'(?+8:C!'##
@r9610
TGANATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGAT
+
(*#")%"$&&'+#'$)$&+*$"$$+)"'(+#*'*&##'+!$&"*$
@r9611
NCCGTCATACACTTGCTCCTTTCAGTCCGAACTGAGCTTTGATTTCTGCGATCNTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCNGATACAG
+
$D894C0,3:B759=C0(9<9H"%/$"0>8?"G#G?;1)F985**3-"(@-13A,A!;-C1/!G38!C*8/2C?:'@@C10D7%"31'38G##(4F/:-68-G?1B9,=.39H!;.@!E<3B:@5A('G90?<HB%208D1A?-<EH!'@-'>%C#'05.1+E-,+081HGAFC>'?!G1+5134)2:E-,1,:=?.&+F<?*6)7+'763E&52=(35;F=!.H
@r9612
TCATAGTGTTTACATCACCGCCAATTGCTTTCAAGACTGAACGCATGAAATATGGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTT
+
@6!G8,$F8.4$@+:)04&G.)4-28(7)-,3B-G2.,*?A(#(A%(:.E49%407@3$?2@(,00?@3"-<.9,42902045H8H?H91C?FHGB&:56FE%8&"&):<9
@r9613
CCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATA
+
G1>"C8=78:-F$7(.9#*09)+<38&F:D(48973%'B/+.0;BF*</7#:&A(F/.%9*&$*:&5EC)CC-8$>6D@2:$7A+@*.17?':$!#;9;2/6#F9>23-=#("E:D7A>2$3/;C))*8#>3G4-6!,&;:(*2D6&"(@HF&$21B2,B1>9(;?/D8=68-.+@29A'"=+79#F/9.>+
@r9614
GGGGTAAGCGGTGAGGCTCAGATTGCGTCCGTCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTAAAGCCTACGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGC
+
1++64("@!',0G%86==60!*&#%5F*:7-,#"'-+,6G!1:E&;%37A(H&?41FE(!.!*;#54!D<'!3>=0*0/+!+9:)'5"0?%=:(&E<=*0746)FE5A<8$!9#2/;6=3:"36+C=!+.,>,&<:A1(,DH?
@r9615
AACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGNGTTAAGGACGCTTTCATTTTCAATGTCGTCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAA
+
87:?1(D7G*"?"!B-EH85%-46B,4<6&D#AB<CD4$,>$:;AD1BD//<="+641C'2B(F7A?9-3;C'638.2D?1*&60+-8<F'G5.,'0!AAA*&''53*2AB>>6=/9$7&%5&+/.2A$EH:+E
@r9616
GCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTAGGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCAT
+
4:E>E)$3E+G1:0$"4=?)G0H6</C(>%8;=:8GC?8'!98.5,7:35=;5(1'@&B<8#$CAF:2BF..>'6C=?-D6&'+"%A2:<C%0&#3%@2@
@r9617
GTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCGCTTCTT
+
7B+BD/G?+>:"/D6&::0%>17>"*$>#5;&?6*:6=CG&B1:#,#0C@
@r9618
CAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCNGTCCTAGGGAAAGTGGCGTACTGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGTAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACNATCGGAANTTCACCAGCCAGCCGNAGCNCGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATNAGCAAC
+
?&2?A%11'A"A!;.58%"=%-5%;#@$',C)<0&:=GG868F#F,1F,DC.@"E3'3+9<$(D)E$$)%&D07$%4C#167/E<7?;%4(4+:*&8;B6'C98C$G)$?)C/0->,8)#C8?B+.17F><"<##!=.(.@&F:9F%6"BB:F2&D?F1F0*76?@G*-71/<+3&1<%H?!G:G4"%6H&C,G25A!)8.'/5,)7/5!H61&B)1F#(&:D529-+$:88(0!<BE3E*:A43
@r9619
TTNACCCTTAAACCACTTGTGTGGGCACGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGGGAGCATGAGCCCCNGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTT
+
(#"#"*+(")**%%)&+""$()%"(""$($&))'*&&*+('$'&$!!#!"#''*!)*#&&(&($($!&*"!'&$'*)"$(!&#'*'+*%!($&+$#"$"%(#+%(+%"#"$'+'$++&()'$""&)&'#)*!("'"%*%"&%)+#%+()"!&*"
@r9620
NTCATTAATATACTTCTGGGTTCCTTCCAGTTGTTTTTGCATAGTGANCAGCCTCTCTCTGAGGGTGAAATAA
+
%3G#2B>;-%>?&7B3*1:G23G.2>HB?H"F'61/C0D@*3$.*$!15"%&H46A2H8%".E.E">/$>.E?
@r9621
GGTGGCAACAGTACAGANAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAG
+
%D<:H*F!>3)>:79'%A%HD)+C"1;/D$7DH/9-((=<?&F'3?+8@=&>8#@$H+&19FHFG#(GD###7H+G9&$EG31D<H=#/,*=.3
@r9622
CGCTCTGTACCGAATGCCTGTACAAGCTCTAATAGCTCCGCAAATTCGCCTACACGGATCCTGCTGGTTGACTGGCCTATTAC
+
:5.:!.7;3"6H,:(A?2<5:<A(&G7F;17;E-,H$3*)CB-!DF.4#);C)9.=.(!A,4%+EAD)0>!)G,FBG)'5()B
@r9623
CAGNCNCATNANCANGAGNCGGCGATGCCAGTGCATCAGCTGCTCAGGTCNCGGCC
+
)&"&%"("&$%#!&!$'*&+(('*&+#((&(#)+&#"!*$&$'&$"*$!**#+*"%
@r9624
AGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGNTGCGGNAATNCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCG
+
E0EH%9.+G>(?;()=/279GEH?;F.-75*H'C.)'&)",!;,3.;%2)?6E2;6B98C,B(@>.E=$.$=&/<F=,HG2H5#+:1!0$<=27)/-C%1H8&%&2F5C)!C!'D).83**=.#'"#G(4G4>"<2<@?0+:
@r9625
NCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCNGCGATACTATATATGCNTTAATAGACTATATCGT
+
#$+)"*!'"')&$&!%$(+(!#%)&*++#"$&!+"%&(*&(&$&$*!#)%#&*+#+#+%%)$'#&+%"$+##***#!(!!+()"*!#%!"#')*")#&%*&&$$("*$##"+'*$$&*'#($"*(++#$!(*%$*)"&
@r9626
GGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATANCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGCAAATGTGTT
+
"8+##9-D>0E@>CH,>53&>&??.$"42-E>#G+;%8B&5=02*#F1(>$+:*=;+H?F:(&#:()+8@4"3G*2(<5D)-*#EH=-%,6#4E%(',-,C43)>)6B"$<:1-;?:D=*+D!0)>*(*&'(7891C/,=9&@B0#;)%*#$'(!,/B+&5"H2:2/+5@29$4&:<6'0
@r9627
TCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAAAGAGGCGGTACAGGTGTTCTCCCGT
+
E.++%6C@+15!7HA./4C+?-<00)1=;4>6*-4,1%''6@6*'(+2".7D)/D>(C?#F3$C<:<-1CF:H
@r9628
CTATCGGATTTAGTCCGCTTTCTACTCGTGATTTCGGTTTGCGAGTCAGCGAGAGAA
+
,2?(>!040(D=B"@'(E!7+HA94-$66.6>&)":*F.D3B(31($0FA%,C'"@G
@r9629
AGAACCAGAACTCANACTGTACCGCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCANTGCCG
+
3ACD#:2AFG(C2GC2(#CG)A9%21,(")=E#%",,:!3$9F8="@H./<1E?6F(%=,0>+:&D.28%0>04(;G;62=E*!!E6GD6%A"&+E,AA:G?"35C%)=;#82*8?4DD#48B0=768C'&B0D'<%.B4+H;F&*$)7G/?0+!#?0/9-$8(98.9"$"4+3F6*!H'@6)4E2!AA3BH/'5-H!%C<B!G1,<:3D=):!9!8H.9B797G!>?>6)D=:!'"!41'&1>D@7@?;%8'
@r9630
ACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCNGACTTTCNTCGTGAGGATGACTG
+
>-,$&$78=B5:F/=E?:<A=";)A+:;:6/BA%+40/3,G)$/8F>!4?88@7@A=#(/93G0FB(-
@r9631
ATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCT
+
D)8"&-,()H&$+"627F<7>/@'##&3/>4AF6.A!82F#F>7+.3);42/.!:;
@r9632
GGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAG
+
D/:@2F%@20>$.C0.#%A"*<</HE0.&+=1G>,#>07H:?@9$9*?D0
@r9633
GNNGNTNTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCGTTTACCT
+
#&!*!$&+$%&(&'("(!#(#!!&(!"&'#%%%+#'!!$'%#"%%"+*##*'
@r9634
TCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACANCGGCATTATCGCCCGTCTGCATCAGGCN
+
@?#92"7/B(8+/-3:<E$<#@8#>!D>#:!1D"#4@)8/,"%@>/E@3?<%54:1F<73(';+/F'F8#=275&2<>;,*%"9=7?25+
@r9635
AGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAA
+
CE$,.):A6C!#0"%ED")=1'F/H60;G@;=-,:@.68F!7',E""6(32;9./;5.7A*'E+:9DF(F<%?FCC70;6E.:6?E:!',G->@B5)G4:<A<?,
@r9636
TAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAANAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGNCAATCAT
+
>21B1(E/.,)D795;?E:6527$)H-E/A<A-6=!AE6-@:A9>!9&5(4(+C/G!!8$"HD:5(0,*+C8!-!;:%6B;B=5(0A#36D"5A'95=D?,)<"%-841A(=D?5DD6H#!2?(1.::2+
@r9637
CAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATNCTGTACTTTCGTGCTGT
+
#?:4!2;E;D*&GH1+$1@F.;)0$42.$*71/&8+!;5C'*!0'=FF2;)!D3',
@r9638
TGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCA
+
87>?"%7,1%0%"8A46%&0A+*@73(&GE3G1.7/:E#2672A+1:-,=<$E:,%C%/9:/.?57C127H=44)G.42=#GG?)H(3(G>3*0F(273@5>9>(-5%.111<9-(:G+05%<.!,A/@,6'"1
@r9639
GTTATTTTGGCTCTGTCAGCTGCATAACGCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATNACCGTCNTTTAAAAAAGTCGTTTCTGCNAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCNAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTATTTAATNTCTTCACGAATTATTTTATTGTCATATTGTATC
+
2553;<H;F2B@6+9H-*0)G2<2=D0.':/6G>81+D7#@293-84E1H8$14B+'(:95:A)8./5;HG(+!'H';CF81@&B+-4?2154,GB9&HA89>6#%>!DAAE-6D>$E+>*$<)18+?%=974;>C'&7AE4H8G1;;.?(("8D1!A%52;9=('+CH9<5,E*1&;77/&B0/$+$:&$,F'2:EA"0/&.46GH22.,F8GG1B"B8+9D<:6:2@,?B#3"4D/5%>&G@#;**=B.F4%D45)<&?->(7*&C*
@r9640
TACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGT
+
GGFEF(8?5?G@3&D!"<A6#-G5&?$,G@E.)A%,<7+DH(,46%:<'2)AC=H;593H6,/=6C1=7CC*#(C?E7A580</2!<ED0.,40CH/?7C.F;9F(5;(5
@r9641
ATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTG
+
G#CH$9?A8@)':4F?4>C+2&9%2?'5H#3B<';7)3%=3<10C@>"=F65FG'>!E>+#4%@?":+'44?G/(9C.8C?G-*E*989-40HD07G$'2C839'2'06.<-"/<*,9&D?,G:#2ED*,<#E5B!G6-H:>7C%E+6C)0@-9
@r9642
TCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCATAACGGAACGTGCCGGACTCGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGANTGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACC
+
3E9)9B-0>479?0<$88H5FB(H9#!G!H#@0.2;?8>>-!58.F8<-C#"GF9-7@-%-);?#;#01'9%93@+<>8+(9C,A74(FH9/#4DA"E9A4>$=A&"7G0&3'?&(F".C0<4:C"H2FEF?-)@;BA"A&C*1
@r9643
AANGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCAATAGTTCCGG
+
9/?*!8+G4;+!(#'/)%/4=-<0BFG&6#1F6B$-H-#BH6?9C$.9.8B7E:F!A&"#)9#.A,?76FA9%"0%G,@.&.-%<&73@"C'$@#!#5E2@C)0GE4
@r9644
TCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACNTAACCAATATTCGAATTGAAGAACTGANAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGAGGAACGCACG
+
2:AC5-%:@&#E$"(#(!%22B@C46*,4((&BBB'*/3C2?':*H@H",4CE@:7*GB*F;A3=&(=#=<%%C:&7)8?%GA"(//);(.-<F;"%2"$<H)EB+%*A,1=%(G1<*,(EHC1(99;,>%HD.,()<$!+?8:F%E/AE#!5B&'6?G8.!C(-!!D45:+2>0H+!'A'4A.E'3
@r9645
GATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAAC
+
9(:27#-6,H744$8*A=%);-0*2>6H7*(412-F1E47.$()!C4B>&."HF3G1(?-G7!.5>-(9#3A32"6G-A6;;<+(C)1":@=:G96/+27/:1,9<;1@*17#C'.(0=
@r9646
TTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGT
+
6#274-2:4?C9AF*.H!G:>'H060AG)HB%3@<+$2#)>77A(*!-<>6FA&B2(9(3G+>>D6'&?6$,EGCE9A(CH+!G436/E;6CH60=+BG9*@5:F7D-#D47$<!"A:!3*=CE+.3)9!0<AA';
@r9647
AACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACG
+
&0D+F)-:-@*/19?G(B&&D(#$@A-));=D>E$'E53((F'.:0/7:G3825
@r9648
CCAGTTCTTTTTTCGTCCCCGTCAGGCTGACATCACGTTT
+
1'E;&'>!F9%43&'7#;:<@##)"5D!BBBH3.>1'0%<
@r9649
GGTGTTTTCCGCGTTACCCGCAGCGTNAACGGTGATGGTGTGTC
+
E+?;=.+6-*9@D6G?/02F/A+#B>#0/2&%1://1!?3>4,/
@r9650
TCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACTGGCAGACACCGCTGAACGGGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGAACCCAGAAGTATATTAATGAGCAGTGCAGATNGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGANCAATACACACGCGCTTCCAGCGGAGTAT
+
3A=<D4!E%::-8.7=&??GCC=74'890#52*31>;(=+A85E-HDEG##=98E4;FH,&GH*%F=C;D?A53AD6A56A;A5#%A+C:9@B2(E>F74@6)H>9?-9.*3!F!<(32)H-!?%&%.CF0(>5!:45+4'B#>@!'7C(+6*C4%>6)?71;(,7@*<,-A>)04*E?6EG(>E)G!0:C5<C1?G5#E0GB76+?(2()(.!1$>"<4<,>;(-55.HD(3<">*8$
@r9651
GGCTGGTCATATTCATCCGCGACAGCCGGACCGCTACCGCACCCGTCAC
+
A'1&@9A=8?/EE0B4"?0D80.'275#.A(%H)5@2)':9*)HBF).'
@r9652
GCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCA
+
GD61?:#>4G*+.+9=G.91)(.%H8&%7A3D+#9&(>>5E=-*7&D6./:7;;<G
@r9653
TAATGGAAGATGGGAAATATGTCGATAAATGGNCAATACGAACGACGGCAATGATTGCCAGAGAACNTGGTAAACAGAACAACAAAGCT
+
7H71<4G<GA)B7(25+=#')7?/(H+"7B.6@F@+H967F;(E1H+?'8"&=H@$%A<1*(*..@2@FFA0.&!,-A$G6F+#G,,%>
@r9654
GTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCC
+
)>H#F!,',B2:C1',#)9"!CB$5<B8+F:2G3,'F.F(%/-D-B.)GF6'283*CG,-<?H<5"@D/C:0.H@-@56(@*:!#(7$*G:49G*"&"F)=H$G1G,=$1'A:9$4@B3"C3*8;.F*:9$99=//4H793BA-7*>C7>DD)+2.:%?)CB)H/6;'(@).0><(7126/+2&#:2/B73.8!#
@r9655
CGANGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCNATG
+
(!!#+''&"'*#$)+*%!#&#+$%%&())#$"!%&%"(#+'+)%*#)*++"*$&$$"#
@r9656
CCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGGCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGACTCCATCGGCGTCATGATGGCTCACAGTAAT
+
H)7/$7:!@,E,6'1*0)%-&6;=<);)=3:<A8*2<G"C:.B&B#G,.2371/'.8<7B651H,7>/H).!;C(>9$E%8=$"E$/7&=;!/D!"7AD%9=,1(1$(*@=A9<G43D$>F*&:8%+BE?"D<<4=B+"69-,3"#/F.
@r9657
NNNNATNTCTNNNCGNTNGANNNAANATAAGAANCNCNTTNNTNTGTATNNNCNNNN
+
#!""#!!"##"#"$!$!!$"##!$""!!$!$!!!!"""#$!$#!"$!"!$""""#!$
@r9658
AAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCNCGTGGATTGGCATCAGAGNTGATGAACCGAAGCGGCT
+
+G>("G(G3C#D:D4"A-H.E$''A;&-&80;30">6<D*&?.C%>@6%C.-%F=,E"<E9G;#'F1-E&6AD+3+C
@r9659
TCAGCACATNTTCCCGGCTGAGAGGGGNGTCCTGACCGGCA
+
)HH7F*,G8H'#50?D?$=DF=@7'*FA!3A+->8G'!;+!
@r9660
TATGAATTACAGCNCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTC
+
6%(?G'E/DADD94/F?8%>5C0?08327G?7.$/1(6)!3F!=,#7)'$&@<F*&.?C*9(-BDG%66=177B+>6D7)=7'*E=74A6H8BF8496D2
@r9661
TTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGCCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAANTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATGGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTNTCACCACAGAAAGGTCGTTNTCTGGC
+
<F%%9G>.<*D8%&(D0$<F:'*C!(CA@E%'.G91B10!.%?2-$,5<6CH#!))'<C.'4%(F>+"/6?8H@7D-<=D),,'1$F5(%8@-$:F3:C0+?/%D48BAB$":)0.:24=5?A):/BB1H$&(;>E)9,':!$.)>?3;@2&-A11!D42EG?.06A71!8-=7=8')E?%<)A@<B9>=:+#(&2G$7!.%(6.=/3,FHD7),D%7'399C:-@,%.::!(8"2D"4F#-((H4'87>8#"#A1*'1?D5((!>!F:,D3'1H#D5,03DG0&"/GG".';#9!'4>H%E'C';"4>F?E3+,>!,&G+4F9:=9%2+7*;D,"D%'0G(G
@r9662
TTTTCATCANTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAA
+
?23+7;*2:!+.%BC/3-@#./$C@&60(E??H)7)(E,-B)D5C<.H39!'&.=;87$:3)95"A%1B&?13A%?
@r9663
CCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGNTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGANATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGC
+
B'7&35$!21;.C;:6A,H9$>85G4*6&24@@G4G)!.B0%:D.79/<1(G,9-"&%+;B$G32H/D(.=8&)E?F6?G'-A@*>$4+7B7-=(@F'%+:2@(=4A4C=?A#BB'C2+;2-6&:>298-3-9;-"<(5;:(,!5;(59!7B:AC";$4(>CE3.1/?9B*C@.;F3,(438G=+#B,
@r9664
CGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGGTGTATCGATAGCGGTAATGCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATG
+
!4H6B$093;B;9+(=7<G3,1;(57$G:C;="//4*G66-7,+"F&B(9)<3'<:-8H"&,6',9+(78H&<1F%*<3);3->?B.,$?4*@:8*5(E7*",G-#/@6'!<)5'B7.#47#E?(A0$GF<(+D5,E>**)4=$!'>6??=D.4>$!HF*5A?-6#;&>:#2;,D%*!8/-+0%/B0,;F*7@2=,//AF53A$A)))18:(>+=<,4H1:5>:C8>$0CF=C3,$0@?B7EB$A17-*#/H:1);D69,C*:?%H6D,FA=>9=32E=9;GH:1G7:751&567*<=@D>7@9&#%(873E0:$G5.H(3'@!4+>B;<86@EBDGH<=.(,?DGH257&>EB+%B>4
@r9665
ATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCNCA
+
=E/0"GC18$9GDBA2(:)73098$$04G#!;!'('D8G)>A#+&)A3494-8!C+4'9*(40350)-B&)C'=DF,@&7*7",CE0(53*=6$$F=8(2G!/G"&D(<
@r9666
ATTTTTTGCCTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCNAATGGTTGTTGCTTCCACCA
+
7.)4=85#4:H(5<D:<9+$$(H57HF@-06:-)H*,%&''%4(B7<(007:)?-$&G$?)&,4(@C9():<0640A@$F9+E0?9
@r9667
CAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCCTTTGGCCTCAAATGGACGGCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAGTGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTT
+
>@32G+A54G.>0#(76D)5/+F#0<?0.598:<@09=-DB07$!E<3#8+HF7*:H(0$C9C@0(D.C+:D@C7D%-%:"!E65=30+)90/=&08&28'6!8/,C(>:6&#1-79/C62::1</EB-)A""34,-9F*>D!0!+<<8=!#C1%H=<6/;@E?H)7>1"(E3/.;@*H3!(/G/B91:=?CFB>:%
@r9668
CGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGNTNAATAAGCAATACCCTGTGTGCTGGTTCCNTTAACTGTGGATAAACTTCCT
+
()D7DB07#!>64FE46)<D-;%;(*26/6>8B('%%3<!FF3,3,4"C44@21""#A@.*6&.$:>@A+$+/+4"%84+*+/#31&'#(;H>%..#%DH7"%0:%A!*?<1.%9%E-:>40?4+,+05@0H@364.@8AE6=+4
@r9669
NCGNTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCNCGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGNGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTCAGCGGCACCGCCATCGGGATTTNCACCACATCAATGGGGTAACGGNTTTTCCCAGCCACACGCNGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCANCACAAGCACGCTGCCGCCAACCTTTCAGGGANNAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCNTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTG
+
('(#+&&$(*$$#+(%$)%)(%"*()(%$'"!&$)')"(+*&+%'+#%&')!+'(#"#"$&&(**"+$+)&(#!&+%(&$*#*)"%')!("%$#)$!%*)'(%+''"&&))+"#(+%#'*"'*"!+#'$"'!+)&+'('"**&%)!%$)%$*##&*(!*#(%+++!""#""!!*&))+")#"++*"%*&'"!!""*#!"+(+!'%#$'!(#$"+%%+$$%$'%%$*+!"%**"#''"*#$'#$(#&'&*%+"#)#'!#'*%'#*)&(!#!('&''$('#(&%**#(%*)(*"&$%$!#%($&&")++*&(&&!&&%"%()!)'+%!+%)!%%#((*(+*"&('&+($"+((+(++%)'*#$*!&%(&$)&%+($!&(#!!')$"*)%!#)'*(#)(&!')$!*#%"('()#$%"#(!&**&'#"%&&$$#%+$+&*(!&'%&#!$#(&'$'&(''&'!$+)"&$&#)))#)+#++)&)')$(#%(('*)%"%!""'#%(("$*#'+))$**
@r9670
CNGNNCGGTNNGNGAAGCCCGGCGCGGATAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTGCTTTGTTCATGGCTT
+
($)"#$$*$#$(%)"%*("+&)*&!""%**(##)+&+&$'#$&"&%(+*$+'&*$()$(&&'!*(+*$"$#*#%%+&$()$!+'!*$'*$#)($'"*()')+&$**&#"+!*$+$"!$$%%#
@r9671
TATCNCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTNCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTA
+
04/F('&=%$"&9)&6/*G%/,A=.'%+1:GH724F=H,85.32H=>!."6"C+"95<;F1EF0A)'*"G$0E6,"A97,'%EBEGE5<'#.'0!E5>>F."@E;&,72E@G3*CH%F77:=#4**CF;3:BD
@r9672
AGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTANTGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGC
+
4H0>68>HG0.BFB#G)3-3G"3=7?),$1H6F9;,,@-#H&("#"F)C/:=F6F$D62B?7!*-!((0'(&)!,%F$G("2=%3$4E@751'?G:
@r9673
CGGATAAGACGTNGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGGCGTTCCGCTACAGCTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGAGTGACCCGAACAACGGCTGGGAGACGGCGACAGAGCGTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTNGTAATGTTACGAAGATGGATGCCTTTGGCTGTAACAGCCGGGGGCAGGCACACCGCGCCGGGCTGTG
+
E/A1H'?#72)6:FC8FF11+E72%695%<9''!?%<):<-+G2+4=#6C1@%H/03C%0E:BA)'DH(C<E</-<18"9*B'H4H2"0+-'C#"H!:1542*A/C=;C7?23%*B&;F0/,2E3$7-$+(F+G1B7!0:%G@H/>"A1)2?&%7!%G%'@B#";@HFF@D@F5GBH-9?.=AE.'D.)+8D28,'BC9%'=CBC03@:5C',G</55B3A>HEH)7,%-/:($$90+>H<?15%*-%79>G@/8D
@r9674
GAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAACCATGCAACCCCGCTCTTACACATNCC
+
-(?)2A$(('-*1">:9>03E1#0GC0:H836&70%5(+1G=D(!3;0A&DC9(B)D4?53:<8+'.6@8
@r9675
TCAGCATCGCCGCCATATTCTGTGNAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCC
+
E>/,)9"5/2A=)-%D<89!##86==,HH:9D'="4*)251='()H3?@&65.+!8@!BEDA)$!6%:1>205DB2'A9@B1(79$=!:A>972/*"0D=%0C@@#<?4$0;,8-!08
@r9676
TGCACATACTCACCTGCATCCTGAACCCATTGNCCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTA
+
=,>?6%C>(@:,5*:*G9FD4-*0%G$-,7E(BD2C$!,;-75066D1";'&/4=HC4;E*$&4#A.$5(!8-+D?
@r9677
AAGCATTTCNCTATAAGTTCTCGCTTGAAGAGGTAGTTTTTTCATTNTACTTTACCTTCAT
+
5>G#9!H@).CE47(2?((,<4(0$6313-G7.G!8BG/<8):!3!A?.!4!3?'"H2G5!
@r9678
GGTGCTGGCGCGATGGGACACACCGAANGTGGTGAAGGGCGTGAGTTTCC
+
'E5>&$,!#957:8H5HG-.?.#;D:.8HG+"71D1'.)C8*&>0(A;)0
@r9679
CTCCGGTTAACGATGAAACCATGCAGGAGATTAAGACTCTGCTGATCGCCCTGGATAAAACATGGGA
+
,H"G=A,&8/%!%E712*-6EF=>-1;&.(DD9.%4';8,4F@727481A1$)&:;(3?'2*C#2H)
@r9680
CAATTTTCACACAAGGTATCGGGGAAATACCGTGGTGTGGCAAAGCTTGAAGGAAATACTAAGGNAAAGGTACTGCAAGTGCTCGCAACATTCGNTTATGCGGATTATTGCCGTAGTCCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCA
+
;0"@>'=#%&6'E!/+#$=9"6B1H:<%?:@C%,.*#=F$05-/=/,>?!83AG2=400#G?6A1.(?)-$F%871B3;6@@53>F(>D5(=:4,=G9(:D.&>156'$;7!?C.$F.$.B+"#AGB"<G+D)G2?C&888ACF!!6"%/?#
@r9681
AGAANTTGAAGGTAATTCCATGACCCATCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCAT
+
$*&%+($+$'!*'*!%&)&&+#)'+%!$(()#")%'%)#&!(!&(*+!*$"&!!""%*$&+'#)##!"&!$%()&*")+)*%+&!)*%*#$(!'&!")(!*&*(+$+)!"((+
@r9682
CGTCGATNTCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGC
+
$'$!%!+"&*'$#)$$&$(!'("$($('#+#"'*(!+$)**$%)%)$#(!('%*#*!+'+!+!%&&$("!)$$'$#"*($*%"$"#(+$%'%!(()"+&'+("&('&("#)$#')%+#!)$"'(!$$)(#!!%!%$)&+"&)!"%#'+'!&#+&*%&$&%"+#'
@r9683
GAAAACGCCGCTGCNCCGACAGGGGGAGCCCGTCGAGAATANTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGANTGCGGTTTCCACCACTTC
+
+=<36!#BG&5?/H+1B/:-'8";H,<9>2/<3E23$=DE%;,A&%/1203?G'!+/!8F'829$3G/(*-72!!C.#7-?=),H&%H=(+)4*-4<'28E*9
@r9684
ATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTG
+
A'?%D0?!@*E4-2(F>D('2'H'0$!=)!*(G',90?&BH
@r9685
GCTTTACAATATACTGACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAAC
+
CE7<(#%&=41=%6!>*$(+0@1+,D!?9F"DEAEB6%G=;)BA;,!9;CD**!49"$E-(F8@<7*+
@r9686
AGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAA
+
8H#2/?3>8)4"D*?!*<(CH+==,0,,-8F"*4=H!87?<)/#$D+8F$B0=4)3A564HC>F
@r9687
GCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGC
+
=7$$/>$B36*#D3A5!9D,7"+>').(20?)18=;(;8A(@33'D)#A0235*6;'5E08!1"G$A01<C,+B+H2,;-@G3??
@r9688
ACGCAGGCACTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGNTCCTCTCCGCAATGCGGGCAGGCAAC
+
+!()#+#+*($++#!*)&#+($*+)$*+&+((&##($&#!*(*!'!#+!(*%*"(("***+$('+(%%*&')%((&#%$&+'%+!#'(("*'&'#!$"&"%&"$+#$*%*(*'*!#(#('++!'"$'"
@r9689
CCACACTCTGGAGAGCACCACCACTGATTANCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTG
+
;'H?=;,")@AEG/F*):1&D887E<H,D%(A-1E>>>35!,)4?#*#,3%+8<C<EE72=36676G*A8)5+F9"8,>2+/8(F':111,
@r9690
GANNGCCNCGAACGCCGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGNTNCTTCAAAGCCGTCAAGGAGAAGCTGG
+
*%!$)!#$#(%"&&"*%))')+%&"&('*##%&+%)&#"+&)+!!!***&*(&"''&(+&(!(*%'#$'!$%%"(&&*)"''#'+##(((#(%%#+%!'"("$##'&)$#**(!%*("+'+#$$*
@r9691
NGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATNGA
+
+)+&&%*$&!(*'*%#!!)&$)()%"(&"!!)''***"#(%+!(+(%%
@r9692
GATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTC
+
@1"&9H=G.$;5.>"G9/:&1.*;1$<$>$=!=E13C&??1!4B1&A=%@##+F-38+'
@r9693
AAAAAATGCCTGGTACTTTGCCAACTATGACTCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGT
+
+"("$&#%%)*"&+*!)$&'!)!&+!)($'#%%!")"*'%%$(**"+%!($'!!$'!(%$+!'!#$)+"*$+%#+)'!)""+$#"!
@r9694
ATGCAGATCAATTAATACGATACCTGCGTCATANTTGATTATTTGNCGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTATCCGGTGATCCGACAGGTTACCGGTGATTCTNTCCATTGGTTTATTCCACCCATAGGTTTTANGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACC
+
,3.?>B6,-@CEG8%*A+D4&FGA@!7>B5)A$'5B3B@-">60C3F:H&*5><B5*+(%@5H.*2,E=#<34A?4*'>=173D30F4(E.(DH*8'!((G/87+!G$@"-8HHF5#B1%6CA:$7B.CA6E3H=:>'7DG?1.6D.*6'G#46A3+.(68;(=@/0'5=A(9:1"$9>$5#880<H&C<'HE-=8#-%=9#&<D7H+C,!A1&1H/!#03A<8C%41*1,0@+/!2B3&684FA#$2*2G';9E<,=D/A+:%&09C
@r9695
CCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCTTCAGAGAATTCTCTAGGCGAATCCTCTGAACAGCCAGAAAACGACCTTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAANACCGAATTTTGCTGGGTGGGCTAACGATATCCG
+
2:&>/;8@6!BG6H'A%D"#H%2$%$G&/1GG)A";)A>1#+60G#1?*746+<%&(=/:.AH)$1%!21?(?H/6:>@H'A,,E,1&'&+BD!91/(/52(>D>0.BH5&1$2C,9!&&/9?@0-(%@*:8(142">$#2/!G=A3-(;H,!D"!5C6H)''(.FA#D4/?E+7;2.B5$-8';@@'&=+?,3'&8-'!GG"7!?"#*$,8HG*F;&4=(%+:D&@.)*B2<%(,%'C&$H)/!D2$H&E">5G4/%G=>?6<02?E#6/=")BE/"C6.31
@r9696
GCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAA
+
?/1='E>97%03)798/%%F<9-20G=.'6C3C=#2<;A2:D/+E30C/7-<'14'E
@r9697
ACCAAACAATGCCNCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTG
+
=4B?=+&:8!93,6(5E2,>$D&2#+.(>,0FB%#"9.15B09%05=)'G$E8H1:!)D:/94".-.$(C3.+*2@A14):68/7-
@r9698
NCCAGCCATTTTTCAGTTGCTGAATAAACGCGCCGGNAATACGACGGTTACCCACCACAAGCACGCTGCCGCCAACCTT
+
!&)(($%+)!#*+(*')%)(%$%$!''#%$&$*'%(&"#%#"")"'#$$!)!(#"!'%("%%+#*(&*"''!*#&")$'
@r9699
TCAAAATTGTTGTTTTACCNCACCCATTCCGCCCGATAAANGCATGGATGTTCGTGCTGGGCATAGAATTAACCGTCACCT
+
:-:E"0,&@6"13;0C=8H8H/>##<*+52+!B..1<'1D!8+1F!+6@087'*G4C7H5!!@=2:)"E#,0F!23DEB"+
@r9700
CANNNNANCNGCTGTCNANCNCNNNANGNNCNNANTACNGCNNAGNANGGTTNCTNGNAGANN
+
#$$!""$"""$!"!#"""#$#""#"$""#!!!"""$"#"$#!$#"#$$"#"!!##"#!$##!"
@r9701
ACAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTNTCTGCGGAAAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGT
+
#/#0>0#!FGF#)$=%@>1,C=)&D'9+(E7@G2=78F,@85CE+EF-F77G/2G5C0G@#&:CFA%%9,#,!8$0:2;!H;@'@0A$3/714
@r9702
TGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGNGACCAACTAGGCAGAATCGGTA
+
'#&#++)((+!$"%!"!%*)#''*$(*+((')%'&%#*()!"+&*&$'&%#"*$%"!'%+*
@r9703
CGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAGGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGNTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATNCCCAGCGCCTG
+
47#ED.3HH<;)'C>3>24CF6#A:2:AG%??HEB>8B.8=4=.946-F%&B8B>HD<8)1CD2/6!5:%C?)A::B!1:2/*B,G9BH8!>H#?9$*6!%+A8G)9!F=>>?(?1">069*.-),0'FE::5&*8!3A++AGDB-78H58C4$2A4<FE/D2,%2<84>75C<2+-H00%6=5*GH0A(,(3*>"1%9";@%D6
@r9704
GTCGCCGGTATTGTTCGGGTTGCTAATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCC
+
:>0:H?,(6+?,!2)'76646<>;GG?C1A?DA<&!4;#/7C;",9H#1G7C.#D$;@$%.3C@029B1/A+4E>89DG(!ABF2
@r9705
GGGGCGCTGAGAAACACTGCCCTTTCAGCGGGCCATCATGAATGAGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTAT
+
"($%))%('!+%)%+$%+%+$&*+'(%'#)%(+))))&&"*)#&+'!$'))'*)&$"(()'*++#+!)!'+!%#'*!+&&)%&#%!($+&'%(##+!)#%$+#
@r9706
CGGGAAAGGAATGTCATTAAGCAGTGGNGAGCGCGTTCAGNTAGAGCCACNGATGANGGGAAC
+
;,41)3?5"@.:+4C6;<.3.G=".C=!;3EE'/=9'H$A8'7,;;>/50G/:>@G:*@:$'/
@r9707
TGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGGCCGCTGAGTC
+
40??43.5-A5'%C@=E-AH?,2;6&-A7G<C*F274.&5(6')8;7&,5=;<9%(8;549"EC$3C#)FA,4HB:C!'-G%4!/1'H*+;)H#)&,$@G*"EE83A3E(=?4--$'5.974/C'?'37'C<?+C-/CE&A7?-1HC/8H6B>!$(+485,98H5&10<$
@r9708
ATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACANGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGAT
+
.!B28)-"G3190(-#G%'F,;B*,1'G?FFHA9!7-*4F$;E>#2(-5?8"8?1?=$*+2>7?$3B./H.0;4/!G#D:0:H.1!'&"@A/@;%/5<E(6=';":D:&5"C33"B9'D1/#4&/8B?<5=<D50'&6?!#B862"8(4H@C2:=1!>-.ED/%06'=66?%>-'$C>:>)CEG8)B2<(EFD#(C82>G'C-738@1>@
@r9709
TGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCAGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCA
+
7.#>BF-0,$3(';=*9C,3)"E(FG$@':D.(/!:5+=27)+(/F(=>1'3EAD$2,!BCA:.<"?(*A)"?*+D?!4!4:17?8G+.>11-E!1="50:0F)D*4+/2,>"+*,:(3930=)93A;B'5'6*AD;;+4(8<;D!7(=.
@r9710
GAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGNATAAGCGGCTANATGATACCCACTATCGCCATCGGCATTGCCTCTGCATCGTTCATTCATANATGCATCCTTGTTTTCCAACTATATAATTTGACCAAAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGC
+
,B;&,%D8'436327-1$*?B>#(.*17+"F%!-#9D./F7*,*?=ED"@/(9<?*D3"0CC=(**F(*;+:.0!?#7&A%5+%1H"<B%1"6!,4?<*#:4A+EG-F)0$7,64D)F:',208/CF=+6.9EE.?6=.>/AD01=)'/>CEE:.2-$@1.&5A#8E/&0!$A=7(&CGD*8#502B,%?7/&3%2D&1$:?)+,&4B&A<"(B?+H@*;6-6*D04!>G0*@$E3%73F;(1?%.$$/A<'
@r9711
NGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCNCAAAANAAANTAC
+
'+?),#<@4B-<:'00"/,DF;!>B=E9671%18(:%H3-A6<A?7:)F;E&$$D6>D,5=*F</+,H,"G8F4-9!9D4B7E>3/
@r9712
AGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTNGTGGCGGCGCNTCCGCGTCAGGCGGTACAGCCATTC
+
082A<1+0B99B!6'5G/7FE*8E/:E)/4?!"%5?4%,/+B)8<"*<&AG"/<1F$'!5,)9(G2%%0HC>61(1>2(==&E);/31CH:?/&3,#-B4&610;>:";?D="F(?#12&G,#>,25E(2E)DHA3A.$8*8+BH@F;$H
@r9713
GCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGC
+
>2()(?42/7*1>7($C%AD@*6@"<$7.G,+-.-&F;+9AF@!<>#F+CF5'5A')"'47<9:7?31
@r9714
GAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACG
+
-6:GC3:"=G;:"E$'>?>9600+/@3C(0G3-+<+#!3/?+8!'4
@r9715
AGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTG
+
$@C;3$-<8?AH(8'$3'A"#CDB$+-277%>AH&H9BG82/#$25G*0
@r9716
CAGTTCGCGGTACTGGANGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAG
+
3!H7)*@),/F)A(*>8)-"FD";24:?76FF:%16=+!H5"*:2E&(C$B$@(/)/&6/.5B78#$HB(5')G"@F;6H2
@r9717
NTNTTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGNATGTATTGGTTTATTGGAGTAGAT
+
$)'4*!#&BH)@,)1>GA$3E(*9#;+41733$<(49;*()%*D@!E;<H"B++E:@&;$5-%.*2@BC/;;:F'D.H"9
@r9718
CATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTT
+
4-D34-HA$2.E@#G9HF*C:'A"11.-8!G09H,16G*''4A72#.
@r9719
CTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAAC
+
,:3<A9F=D*%&6*'C"=E0,-<$6#2H;B>G:+1.186$6%6:641/B*2>2&>%!'1*57(#6H=*B5704"1
@r9720
GCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGAGAGCGNCTGGTCAGCACGGCCCGGACGAC
+
5E&D31$4#D5"=98(@/C-!8>0H)DG4458'%+2A*$3@/HC1,1*D#BC4:5.+9,,%5E+H5FA8=<HD)G1*H>0-,.!+/#G;*;@0/.7@,3@G(AG":2
@r9721
GTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTNGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGNGTGGGCATGAGCACCCGCGGCCCCTGNTGAACCGCNCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGANGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGATTTGTCNAAAGCCTGCCCCTGCATCAGGACGTAGCCAGACGGNACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAA
+
@>,:'E;!$+'.>4<@187#*E>?8GE:F*$&G<9D>;9&3.?A",4*D6<B$,G669<B5&F"C6:>$6@HD+3*,*E+.-"3;($)$D"(A">4%-2-!<=#;#8.8D5"(20/11:HAG"#D>,!?D'5!;?720"BDC4F-)29)14-B%E4&03!+A,10)BA'=DD":"?.B((-%(885<+G@:@%3%F)H;7D)-+"D?4@#<E6&,;<$1(;7%3<;!8>?/3C)#/7H.?@:A3B=)F5D,-@8"G":>2/=9,='<+8#!"B(,*#B"2D08.E.:775/3+$)8<GH))01.G(;.*&@3.:/#";E?E'1D4D)!%.)2>!-8!$@,E#<*5'C!$.3:>8=@8&0@G&@0CA<@-:%!$9CH-8?B+GB.16/##D0%4<.H&#9422/1(8!*!(.+0A%0G<-0G$#D&1>;8#4037.):2:2$(%='!$!=**35$7F.(",23'%'1=62''<&C7*28+$+GB5CB<D=H8D*;.H?@,://5"7172+>E+%58HBFC.(4&(E@H$="&/+%<9#<15%*@@:2E.@14C0>GE*BC4E3HDCCD7(;F/A"=2>*:,5'A)H?H(04G2HEGH645<;A(A8:)"C0$B*#(+46#/=B8DG2!;GG9C5$G@E#9(8$/%;(!1<:($8F>%
@r9722
GANCCGGCGTACTGTTCAGCAGCACGCTATTTAAGCCATCCACCNGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACNGCG
+
("'B8'C41%&3";9/1F=5(==81C&>-0DA55;<.@<79,),.8.3<3HCCH"B2E9A29<3?(+GDB?@6A1'0.9'>1@9%&'%6+)1%19=
@r9723
CATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATTATTTNAAGCTATTA
+
@.(D"&(9&?C=C8+5B:BE%004?D&2H>%3A'18GDE,!$66H"C<F6D)1!89F,7.0,&*D%=!!7&A%-2.0*8'6$$+-&-"0-+5"@8>!H"4D9,6D-8(F83D-A@.7%<(+HB$A20H:9*,D$A''
@r9724
AGGCCGTGCGGTTGATATTGCCAAAACAGAGTTGTGGGGGAGAGTNGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGATGATGCTAATCCCAAACCTTACCCAACCCACCTGGTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCG
+
6G1#54H(A?0!-:<.,#/,.?5HD0!1H/,'=985;#@2>D07A77+B&C3EF1$B&991>E1C1GC&)&8.$B;,./=)A5*9/G08!B<)2*G5#';B(+H#=;.+E9?$+60*=(856!<'8!=*!=B'17.!<"557%2)-+2G(1<-A59$$E=C-@38:4+/7*6#F.>.;<40A-=D1-8",/*,H606$'DA#'B/#"*/H5#%+4@981@?DG5%&+G<78E8:>8/9/C0C92!;1E116.&-2#&:F2-7CAA7G54&"'B:BADDF$(H:>'/-D.;>;/.?2)*!869/$41-#AB)#(?78>*"G!;H3/$3;*?=+8CGC;8$0"*%6BA:8FHB:'/E)'G486C)'C+3:&A)12-&G)(6F
@r9725
CCCGTTCAGCGGTGTCTGCCAGTCGGGGGGAGGCTGCATTNTCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAACATCTTCACGCAGAGCATCATTTTCAGCTTTAGCATCAGC
+
G496%(>'H/G?@,<6+20E%F450".0-87@1-G;@"GE@B%3C"40.@7#@(#A;<G7F;H5'>C*A9F"4>DG%3FF5:CA10,1E7/4B8:8G'8AA498?6!$>"1!,6+5.#<+*C1?-4)+?!2**60=*#&)F1)38,1?&35B#5H68$!5
@r9726
AAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAAC
+
+!$+*)#$&+'%%#&)&&("(*++('$"#%*+""+$!"*'+)%'&#%
@r9727
TGATCAGCTCCTGTGGGTCGACAGAATCCATGNCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTT
+
/40),+=9H0*C-,&C8>2;9#7(-+9<G883(4<1/C,F'A0.9?;<#/!6#=<<=(9,:329+BD*;7$27G(''DD>766=HGHG
@r9728
TATNGTNNTGCNANNNANCATNNCATGCGTGCNGTANGCNGNCNNANCNAGACNNNNNCAAANNTGNAACCAANAACAGNGNACCNNANANATCNACNCGNNGGNGNTGANANCCTNNNGGNNNGAAGANNTANCNNATNNNGN
+
!"$!!#!!$$"!$$##""!$"!!$#!#"$$#$"""$#$!!$"#"#""""$$$"!$!"#$$!"#!"$#$!"!#""#"$""$!$$#!####"!#"$!###""!!"#"$#"$!!!#!##$!!###$#$$$$#$!"!"$!"##!!"!#
@r9729
CTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGNAGNTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGG
+
7#?F+D.D"6)35E=A427?:2:+5F''*"<BCC(6;+):3:5%GDE"E!,/=B!,*G1@G"#A8+.+8%E0G3>%&90*?H4=*HH&C-DG?8E7BB?"(1#,FC;0
@r9730
GCCAATGCGCTTACTGATGCGGAATTACGCCGGCCNCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCG
+
8!:8/<!4?:2)+6)D0)+'2F?9*7:%#"<9.*G)2<,==BD;(*6=!:$$=18C?1&2"570(/?C6$$*1
@r9731
CTTTCCGGCAGGTGCNCCGATNCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCNGATACAGGGGCAGGCGTTTGACAAATCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGANGCTGGACAATCA
+
+*$*"''!%("%"'"&*%$$++#'%#)#&#%")&#+!"!")%%*'!+('))%'"#!#+*!"+&*%"#%"(*$&##$&$*!$!!(#*)"'!#)+'%%!)"*+$)*'"!(+!"#*$%+#+()+$#!$'*$+'&*'#%"()$'$!"++&"'$#&&&)(
@r9732
CATTTCTAAATNTGAAGAGTTAAGACGTAATGAACCNCAGATTCAAGTGGACGNTGA
+
8B><C"44GA@,<0*:H/99>D:G,7<A)D;3D241!3?6&BFGE+8+!:*7$.1&F
@r9733
AATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCNCCGAGATAAGGAGGTCTTT
+
4)#/@B%;5551?;,D;;0/!&,6A#=*A89)<C-</-7;.0(FC2/+5@B6$8.2?@?>1-2&6E01E#4F3$GE2=?9:?H&C?=1'-*E!)/B0B=".,0D6&:4C7//70$.G#.47;F
@r9734
CTTCTGNGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCNGACGTGCTGGCGGCNCGTGCTGAATCAGTTGCATCAGTCACAAGGGCCGCGACCTGAGCAGCTGATGCA
+
(((&&&!%+!("+$!"%%*()*&)*)$*+''(+')'&"))++++)**%#+%+&($')%*!%#$"+'!%*#+!)$"$)%%!(*(&**)%$#""*!!+&)"'+!(&+$(+#+)$(*(&#!(
@r9735
CCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGG
+
>.<<-B?F+,(&#9.F-'-"B'B*,3(C))8):A1<(*,5,,=.%@">.BEDC03E<>"G3B>=/6
@r9736
TTCCATGAAGGTTTANAAGTCTAATGAAGACAAATCCCCATTCTGCAATTTGCGAGAAATGACTGAT
+
-=$#8!E=F+3&:!BB31;%A;B+4C10'A*838A/,G:G4*(A92*;1(9&$5;>?F?("''<)9=
@r9737
TGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATG
+
->,=)C$D$A+B$.:**FA0EHDG;2$66("/B2=+;'A%D62-5&;?6;$:=)*//=G8+)G+(;6+HE(ED7!BB#"=24!-0?<&*A-.+!)?$0,A&B>?D@1E6?;"
@r9738
CCAGCTGGGAGTCGATACCGGCGGTCAGGTATGCCACACGGTCAGGAACGGGCGCTGAATA
+
7B-B:D45G>F%=%:(33$;':=.?-09?3><!?BG'1!/?):$G#1F@2%-@50@(D*!<
@r9739
GCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGA
+
C;<%8!$%65-/-;!="C&3#E)7;EG@)14DA:00@C#<G-$1;3A>&=G.B:*%1,@<#2CF8!:4A&&'E!&0.BB><3%E20#/#)&D"$*?!*H<FG32C:@$E9CH#9DH5)"56A46*F/'"6<H2H(?434?E!!"B))'!=;00
@r9740
CNAAANGNNCAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATNAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGT
+
*#'!)#$#!#(+%+!"("+%#(!%+(!)+))&'&$)!%!('))+**('$*'&!#%&($%#*)!"*&#%$'%"#$""++&%#('#&&*)"!+"('&))&&''"+*&&'*!)%!&&)*"$+"'%
@r9741
NTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCC
+
#-2DC-%.A9%!:F?":3AAAFC134<1)&&3E&%.%:E1=#F&B2,C/#-1&!F8$""BG56!4E1-36D<(%$#@B<11)6HD.9"F7HB=91:&;412>(!%8BB)(+/<8H/'>:0D2
@r9742
GAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCAT
+
A!%):3:'$/-E((H(E;4(+C'@>?0181(;@1B=$;,5@53G"@!-<67ECE:2;(/:2:
@r9743
AGCAACNGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATNCATTAGTAATAGTTACNCTGCGGCCTTTTACACATGACC
+
)+("&#""$""'"*!%%!%)($%%+&%%#$&"&)$$#*++'(#++%!&$!))(&%*!&%*'%&*)%(%!""%'&$'!#%!!(()(+'&
@r9744
NGTGCCACTCTGTTCGCCGTCAAAGGGCGCCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACNGCGGTGATGGCATAC
+
$>"<5E*('?G?2G,,C9+#A=GB<$9.(1!&B!*B$97#*DD?:@2+F>4?E8((-"&*;@0&D9765'@'36-)G;)5D#E'%.8@
@r9745
GATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGNAAAGCAGCAAATCCCCTGTTNGTTGTGGTAAGCGCAGAACCAATTAACCGCCCTATTCTCTCGCTGAATCGCAAACC
+
BB44"-!%;H>HF$G"B.>,F!*#%D@C-*-=&#,F'F1/+E,(9?D)"#@3%,(5<E6.D/7E>GBHE;)<BA9A"D=+,=)-?94>@AE;1>7*<'A!>EF*<7>;%B*/)='B.BC00!?*<22('$!;
@r9746
CCATAACCTGCACATCGCTGGCAAACGTNTACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACGTCAGGATCACGTTTCCCCGACCCGC
+
%4<9?$67.(H3;3?1(0/!!*&).8F8E<AF&6+).(3@G.ABCD&;558(@1#?,%-F6,BE"F>>C8AD><A<>.93F1A#6B=677?0D0(+BG@!
@r9747
GCTNGCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAANCAAGATAGCACTCGAACGACGAAGTAAAGAACGNGAAAAAGCGGAAAAAGCAGCAGAGAAGAAA
+
(!*&%#+'$)!$&&&)!*+(+'"'#%)%$')%$##""!$&#&*!"%&'%))&%"'"(#&&!#'#)#&&''(%%"+*%#%#!(!)'#+!!(%))%&%$)'"#&*&#%++'$&'$%'*
@r9748
TAGTANTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGG
+
DBF41-8;"H5FE'99E9-3E#F=D0=43$/G>737=G1<!@-%C43?0BG:0),<-.<G<-7H2FC$H)&3),"?H<539*<%1&4*%$9G>@
@r9749
GCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGAAGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTC
+
D%:;1%'G?0HH?:))882=#%/7=0:E3/D$>(D5:G9!4C,"393@;+&!3F8A")0$;(9-:'$&D&!8%$H6()B7/AFF6*!25>H'!HB-2G0"F%2A&((65B/'B#72F'C*C>515G"!*&>&9;15#:@%+26F*F!AC*H(:/>=;8!D832@GG'6'34?&GD-E9;B.39,:(6FA((3@0H8B(FE6&CG?=)1F!>>!,GC?5B6!H#EEF1('3#9!0&A;=.D<;9;(G,(#-52)-*>F1
@r9750
NCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCAT
+
&7D70A<;B(+<9&1&:E+6/E)F?$):C.&(@321%###6@6G9#+"/F>E,A5+H(1@3*;5B>BA&>,
@r9751
CACCGTTGATGATCTGCNCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGC
+
8G045*$;$;-':3-7$>>"=>/H8'3!H)!)6>(./FC)G78EC86FE(&(BA+H7<9
@r9752
TNCGCNTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGAT
+
*!*')!(*&+"*%$$##)"!+$)()+++'&+"!#"(%*#+$&((*))$#!&)*)%))*%)"'+(%'#)&("+$+%*'+$)'++&"*&
@r9753
GCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGA
+
B%9@&6$4EA8<%#*+9.1H(6&=%22A.015"88<"$HG(4D;!-6:*F'2:*D$5&?E+)'47B
@r9754
GCGAAGAACAGGCACGCGNGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCGGGCATCTGATGCCGTTAAAG
+
D#A8207GE.%B>;&>9A5/.6;)>*5#-!@@0*:=;%:E')2.B%7@B.DA4836="(AH86":F@>!D(G<1#@C>85(5>+A/3%@!6#C,"(@;9B1//89H@3.*H0H#67'1H!89E&H%;C<>73&&>G,481=C%%,$.<-?))/->A6$AC(E6*)4"61"F<9A1"D4).
@r9755
CGTTTCATTCCCGTTTGCCGGGNCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGCCTTCCTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCNTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGC
+
F)1.);).HG.F7D//0)6D=-?.-1=B=H0>78?!)=@B7?G#@0?D:GCC.8)A?9,&?0?4C88D+2:5-;B@5FCH99B>(,+3;"992G*#>C9>:+4$)$;6/5'G'&$B!4!E:*%.B7G3>!;9,:>CB&(A)AD=G/#);6'D0AD3&)"-4,3G!(9-G$(:=171B'-B/31AE7ED4?++%'<?./6!>-0:,A:.9GA=<-<F).#01:%+="4(5C7HB)+(<)7*'4/!"-(
@r9756
GTTAANAACGAGTNTCGAGATGGCACATAGCCTTGCTGAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATTGTGGCG
+
+'B$9+1EG!+C*8A,&A&.4F16'"!*53&2A';'0F.F!GF".$.G+C=HE(G917AG&C)F,#=A4G2A-,8'FB8$8=!<3;),>?4.B!#(.,7)/%9C&;-E1E,!G=<G4$0-G:)F7?B@E9H,07:<
@r9757
CTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTNGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGC
+
/+<+D&@5*#E8)E?'2E+/-B?8=*@$#,4AD!C%!-)8:/902+9(8+DC%,G#9%*</*&"D3=30@BGD?8=3<3,!%.@&FE%=:H%C=G9H;3&54*!$$.E:G<E..2!GF?C'&/E/1.4:7-D8A&E(&2!=*@'3
@r9758
ATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCC
+
=;==0(<5@+1A!)(33-:8<EEA(7+'+$)DG8%::?98<C>(3.#4,G?<;(F<&)*,>GG2?'!?:F-:$8941+G30&H&8(3#"15D*/)@./G714&*.<E9<,C7HF+3-.CB&?;8((E6E)2G'8BAA1;
@r9759
TATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATG
+
(-*H7!&G'!CB!:,2CE%H(H%1%A>*8<,4?277?')!(1"&715()*$G&74.)0/+>GBC$,<F&(:?2(@)GA#.H1,.9%H;#?B!:5@'&B'7/>@4,(!@A8+@F.0.:FE
@r9760
TNAGTACGTTTCTATAAGATGCGTNTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTATTCTAACACGATGTGAATATTATCTGTGGCTAGCTAGTAAANATAATGTGAGACGTTGTGACGTTNTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATATTTCTTTAAAAATGGCAACCTGAGCCNTTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAA
+
(!$&#+!&&'&)$*$&$''(&%(!#!+$*!'*"&&'($()*)*&+!$%*$'**&)$#**#'!&'$'"%(##(()"+)""')#'$)$('*'+&%%#%%"*%"+()%$+)*%&!'$!('$'&#+&)'+(&&!$+'*#(&#&(%&**$$'"!*+")!)"!#)!'!)")!&)%#)#"'"$$((#&*(!(!!''()&(($(&!#'&$)+!'!#('"+%!"$*#++(%+#''''!&))"%#%$'()('+##%%&!%((($*%""#)'#+$#'#'%&'*&%!%%%#")!)&*""%**)$*!'+#)$!&)%!*+()"*#$%*(&*%+$+!)&#*!&$+&*!%%'"$%""*'*&%*(&+&')%&##*&+%&(!'&!$*+%+)%$'%+('+$*#"'*&')#%$)##%$!"&)%**''*&)('%))"$%)$$'(')%")&"$(*(''#"&*$("#))"&#&
@r9761
CAAGCCAGAGATGACAACTTCCGCCATCATTCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGG
+
*:&5@4()5C3B!')==?:.".H=@/F908+3)!!4H=&4?&E75%(D&5#-H:&9A)5+F8-9;0'90BCE"++*1-07!-6G1/*@'&%@%4-,.?EG@(A,B3G'F0C$:9C8+:#'!G#3;=+'C3=4948.5A:#-,+0)/06&A1/#+A7#'G7-+$*'>>%41D#-<5?!$)A5E
@r9762
GCAGACTCCGCCGGAGGGANTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGNAATATGACACGC
+
.6H80BDE(?)G"=/F&(6&5D.'37541$EA#FH00.07!C=!!="EC>H#82B',%E.4.@:'G%"!"D;1C
@r9763
AGTTTTAGACGCTCTTTAATATCTTCAGGANTTATTTTATTGTCATATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAA
+
F?"<!@7+;,C"+>&?.062/03%@@2<D!3,!1+.E>6&<";+@(?&A"H5BG$<'2$H1$.4$+3D<+'5A-1@.#5(0@-282@24)21F$+.:+(H*D2DFC82'/<=A2,*<=<.'=1C3!C?
@r9764
CAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGACCGNTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGNAGGGGCGGAAATCTGCCGGAGATACCAGCTTCACGCTGGCGNGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGATGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAANGNAGTNATCACCCGCACGGTGAAAGTCAGTGNGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCGTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGCTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAA
+
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
@r9765
GTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTG
+
E#9/;3*">'!<.'D$32%"?;@H/B.<5-H%?5/1<7>4;-,*1@D:,)'(+C<#-/9!!=2&6>%0>D1,AD?>
@r9766
GATTCTGTCCATTNGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGNATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAG
+
B!$!'&710)4.+*/A&"+#>35/2>0=.#!2:AB,-09>G:EHF4,)F&?5-:>C1,8:+8<8E8&C(;3)?583121$(E4)1!2:3+"C@<#2<"2=)E7575;E0)*4.37/F@7+H$9&E7F.GA/?&&07D(
@r9767
NATCTCGATGATGAAGACGCAGACTGGACTGCGACCGGGCAGGGGCGGAAATNTGCCGGAGATACCAGCTTCACGCTGGCGCGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGC
+
);'>'B033A+3':.46@@+0G!G5570-F@?3@5?.1?"8A5G:4-)0=&!)6E5>G4.!1%!#@A*$"A@(%8%HGG;'C*@4AED%<,-*'@B:256?=DGE+5B4@H)$"!E"(3
@r9768
AAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCC
+
9?;::#(=!'4;"'359E$EE:4'A(A?B.=99.3!*+$#/G9=8#H/!8#<0C2"
@r9769
GCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGGATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTT
+
97')"1F#+%*0&&-7B/D/$<&/.E7+C0C6?4H68@;)6H>'1-4AH-EC7CC.E6F')H,(?B,?"-<7>$D,14BD'B7+++*.>EHEE/>E4/5+4D$597*+#"'.1!"=;7/2@.+
@r9770
AATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATNGGGAATAACACCATGAAA
+
30+96(G,$$#1!7G6/2!)EEB,8"%#(=0F"@6&6;6D<)6<6,5A<"#&1$E4AB;
@r9771
ACTNTNCACATNCAGGGTTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACNATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGC
+
*)&##!)(*'*%$+')!'#*&'$%*#)))"%+*)#%%&"$(*%%*#"%!)#$)'"*)*"&'%')$&'%*+$)#%$"$$'$$#*+(#++!%!('"*%*+&%!$)&(''%#*%#&
@r9772
NATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGTGGGTTTATAAGGGGAGCGGGACCCTTACGCGAATCCGCTTTCA
+
!>FCC6!D.6'"+?(ECD74>!;)BB0;2D5,&!$"+%%31?D!BA3*?&D+1-)=$?BE7D7"=:HFC=3@?G:1C"F@&.=D,@<G&1'+#D(F'=41&&E-G$48E,"52C*$(3G2@;<"5.)*>)A$A$(*>H:@*4CF/@"A"9(A0*<"42*
@r9773
TTNACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGTTGCANCGCTGNCGGC
+
2B60!&D84H399*>:))(5-"#>:&)+635'#,/%@*8GEA,/<A/&+>7=E@+B=HFB2>E?2-=0>:+>H#C"7'-8*GC=-A?$@=/;"
@r9774
GGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACACTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTNCTCCCCGATGCCCAGATAGCNCCAGCTTGGGCTATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGAGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCC
+
+D,/."5%.?F$*E&'D$0>+/C4;66F*,$.*H,<G*)2<$:-5G=)0'D*G:3@$-$8,;28(%>@!;&&;4+./+75-3->#1;-FCF>'9>==:@"%H56&*29)C!B/G76=)G0(?3=5.%BD:;H">%A<(9/.*@D4A<*EF=+3=<2(8D:'BC!?57*570C((@$4:97B):EF6;>E6"B$;22!)+F+B'28'#=18*9C%H+7@2$#1$,$H(G%9E9H9=E%EE/1AA&--?"1+0=E4+?F"%B9"9>!;"427/@'E7FD@6!3+CBE!4+GB5E=-2@;=+5=<6&":088@,<0:&3;(0F4F3@>D8C)5=0G*43=8*(47@:<2$)9/#<;:D>5
@r9775
AGGAAAGCTTGGCTTGGAGCNTGTTGGTGGGTCATGGAATTACCTTC
+
%5"747:$;6E3;5*E>-7HC3-3:BD/0CD=="D=G0>5#G+,CF%
@r9776
ACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGGGAANGCGATGTATGCCGCCACCATTGAGAGTGAACTGGATACGCAGTCAGC
+
E&#3G+441D&@0(,>"0%0"@+D19&";-H/7*6*;@A5&!%G((%*E$*H2+.7F!13;G"2#34#8:+$5!?=3**D!3;&1&
@r9777
CATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTT
+
>B+506(5<)+.A'.+9,;+56(7@;-D.2C$6=$7=&<G&!2+E)
@r9778
TTCCGGCGTACCTTTGTCTCACGGGCAANCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGC
+
(77?5>G7;A#,>"G99:@C++@9+2C?/85,-E/3)C!A9CD>2-46,-7*8?%;:9-C!,23D4F94"B78?D&7$*+8:C:%?
@r9779
AGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATANACACCCAGCAGCATTTTGGAATAA
+
$B%47--6(9E2'(B:*41."$@>=E6<.4#*990/>*2D>4*%?)21.0))5':=A&,#''?!/"8<:/9F1D>
@r9780
TTNTATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGAACTTCCGTTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCT
+
($!"'<D"H(=*(9)@#<H?<HB9'CD?"'6$1)-1HDH4+=:5!@;4'84&G7D<&?6<;B/FE1@)'?63?5F(@#:4411>8&5D@6H,25&%"%5A04,+;F8A!:&9H:>79B>B1,));$.
@r9781
TNNNNGTTNGTNCGCGCGAGAATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTACACCCGGACACACNATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGANTGAACAACCACGGACCATAAAAATTTATAATCTGCTGNCCGGAACTAATGAATTTATT
+
"$#"*!$*$*)"()&"*"$'((&'+#'#"*+!!&%*+'$$'!'*&"()(++"*)$"+!)'((""#+"&%#*+*%'#'"*+#(&"+!*'!(")&&+$%%(#%*$&((')&'')#)"'))"!%'$*'##&(((+''!((*!**"&(!#!(&!%%"*+'*#$$)(!"(*$&+#'#%+*)+")('&%$#'($!$"#%+'(*&!$($#)'!('&&++)+#$+("!)%)&&(+%'$#+
@r9782
CGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCA
+
BG)-7H)5/,A);&"%4>(6''1<77%+=.5-31F!B4)76.$16,@3H;!
@r9783
CNACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTC
+
!#,/$23(*2GB,"?9D5F/HE!.),B04,+2H>,29"6(2$-1'4H5)=1&F5F4HE
@r9784
ACCNAATAACGCGTCGCCGGCAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTG
+
%($'(+')")&%&"!#'%'))%$+(!*%'$'&%'%%&)!)++#+)"**'$&*+""$*+()&'#!"%%*#"!(+"#%$)'!+!"!*%'*#)*)$"$)"%%++%#!+!((+#!!*+*+$$%
@r9785
GCGACCAATCACCACAACCTGACCACCATCCCCNTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGC
+
AE=B431,'C4C!>5%94F?:@/H2;"058<3-E)">,B6"AB?.?=.%BA/9(5/4'%7H<B;G7B,E#;B#"42>F&='(/D!>.+H*#B=#1(",'*+$A(><,!=@*D(
@r9786
ATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTAAGACAAACTCACCACGGTAAACAA
+
*E(G;FA4===-+'"F9,/<=#A<F(B:625:()C@7-4'>5"A7'=&1#E,$9.B;G'G;<-$C$$97G5.
@r9787
ACCCGGGCAGTTTGTTGCATGGTGNCGGGAAGAAGCATCCGTTACCGCCGGACTNCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAG
+
;3F49.:.H$EG'15D3G?(</C'/4DD1:+H621+,59;:#>2AH9#%!F84=:E('?,%C3:9(BBED2$H3B-*%'F->BC(%<(*54106#=01!><(3)163
@r9788
TTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTTCTGATGCGCTTCGGGCTCACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCNCTTCAACCTCGCGG
+
B%3<)-<-EH2?B#@$:G8-5E"'5(3145:#?-/F)%;%;)*9/69C86-26!-&#&7D8:%>A2%(5!6H1).,@B.D/1,7FC>&GE3C=2FAEC<@3/B/!/<,)"6$./2C&?3G*"E.=#F;'3?3'.2*@-=8+@)7A$3C<,;>(5!-C(5=*<1?26G;A)G07#@HH!""-@,)!(@D4&/F/E8%6:8!9,!9G%+!:1"2*1?5%@(4)C>;938%<H%->1-H82%E/6'B)2@C2D,9?%3=5%25'1+:
@r9789
NGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTAC
+
"+'%)(*#")!%+%+#'!!+$$)*$!#%!("$!!$'*"'$&#$("+!+)$+%'*%)%#!%*)%"()'(%!!($"'
@r9790
GCACGNACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAGAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATT
+
?BA25B'%%.*2D6&:?-%4,'C=0F">8A*2B2G:A1?6H%0/;<;/B;$.FA,<46('=C%@32-=1"@&,!+0'-9-@@4H)47*'85C8B2E<E)EB6
@r9791
GCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCNGCGTGAGTATTACGAAGGTGTTATCTCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGA
+
C6?D(8-2@-;2.!B$A>7)E*!H'/::)54C?2B+!B':;),!G(!CB/H,01&,=+>#)H3<09E"975=&B-2&@.3#??!E"3?*/,25*462'70"D/6E>,9)&6'01(:!%0'F2:;<5"(65.@6;4/@$+A
@r9792
TCGCTGCCACTCGCGCAGCAAAATCAGAGGTAAGNAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAANGGAACTGGCTGTTGTTACCGGGCAACGAGTTNGTGA
+
2F"2$*4'.*,?:?6<A%3<)F#FA6/?4?HH-F'4E-*%3:8HA=C3%9+6680:'="4>&0&!$B'6&(H(.38,->./H1@":D>>9C4F(:#G:$:,":ABD+<!#/F;8"/+77H2D?C#5/8E'>'4%2.(H#-B>B1#35!F/>
@r9793
CTTNNTGACTCATTGGNTATAGTCATTAAGCCAAGATTTAAANGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAAGAGAACATTATCTATCAGAAAAAGGCCATCNCTCAGCGCCTCTGAACAAGGTC
+
*#)#"+++#)!$)&)$+&*))%%&!()&(())$!*'(&+)$+*")*("(!$"(&+$(*'"&)+"$*&!"&(&&(#"))%!"&(#"&')!%+")()**!+**"&##*"%))$*"*(!")(*)$#!&&')+&$%!()#"'*"$&+#*#"!)'%"%(#++!)+"+*#'"#(($""%*#'$$$$!"'####"!("&"!*
@r9794
GATTCGTAAATGGATTGCTCGGTTTTATTACTTTAGGCATTTATACTCCGCTGGAAGCGCGTGTGTATTGCTCACAATAATTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCT
+
&H>2+=AD@EC3)<!2C-(D5EG%(7633&0E,+>4%&1=&6>$2HC3=7$8",,51"/-&(=<5$H,2CF4)=+9<#C#AC.+':./7=72):;80,0=B-9F37&7@(/15$<2FB,@8H3%?
@r9795
AGGATANTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAA
+
'6#,?=36(90.44B!5E:!=58%#%DEE%/*D#$E)0511<3@)9B1#-7HA;
@r9796
ATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTATTTACTGAGAGCATTCNGAACACTACA
+
*:E<E910(H*">A"=C+D;%/==;$8D5/)55D28H88$>FGFG8DH4></7H;2*(&70>C)55B7=).*H!@,H
@r9797
NGTCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTT
+
"4'0)C*2E2G5A7B>EG3:@<.4412=&'D?@;:<EG!'*>6>2*6,@5?)*!(B+4!.).'E-FDF.14$
@r9798
AGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCNCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAAC
+
B3C@672:=A27)7G6C9F$/"D3/<#DG*#C@G+(&8*9AE(0F61DG%"#C%/0F>4-A:6F#>!3H#AF>>3-7(&@)CBG63$#'?4%CB?(*:
@r9799
NTCGAGTGCCTCATTGCGTCGCTTTTNGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTC
+
0<!8F(5-)H17=#B$4GE6D/)H,B,?"604A+!-(%;B>%"CB2??9@(9(%63?$66)9'!AAH2H
@r9800
GTTTTCTTTGCCTNACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAANTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCC
+
&0"B).=B8--&#4397"-/1(@8"6'/')'(H0@@BE""?>-78)=33'HA*/-#-@&)-)9$%G3,CE'B:+1=FH>%;FG/9D0."BG7AFA@%9GE94&@,:H;97+DG$9B>
@r9801
TANNGNTAGTATNAATTTCCTGTGTAACTAATTTACTATATGGTTNCTGATAAGAATCATTGCAAA
+
(!!("%$&'*&!$+#*$!%*(+'((&#'#*%&"*+!%'#+*%++%!"*)$)(")%*$)&'"*%%#!
@r9802
GCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAANGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTNCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGNCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGANGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAANAAAAAAGACCTGCTTATCTCGGTGGNCGATTTGGTTGATCGTGGTGCAGAGAACGGTGAATGCCTGGAA
+
+("!'*)***$!!+%"("(!!#)*!&+$*))$"#"(#$)*)'*!*%%!&*%)((!('(#'%("&+)(!')(#$*%)(+)(()'""+'('(('"'"&"+&)%)!(!+&"(#**))'!"!#)'$"!'$&(#%)'""#*$$+"+('+'&!"'$(#*$'!+!#("('!&&#+!%(#(!")*('+&!+"+#"&+%#("")""**!+("&+$$'!#$#)%("+$&*"*"&$#!%&+(#$(&(%#(**'%#+%)$+'%)"))#$'%%%+%'''+&!"##&%%*#(%*($*$#%$(#)#+!'"%!&'(+!$''+*++$+&)$(*"%+(+'($(*+$"*&*)'$'!&$)&'$(%*(($"#&'!+$(#!'&$)"+*$&""$#'"&"*')"%$'+*#+%$"'$!"#&+!((**$!&%*$"&#!&&#**%&!!)!$"&(%"%&)"'!&!$'%$$'*%!$$##!&##%")!'#**!!+'"&(+%!%"("'**%#*$%&)%*(#'#'")))&*
@r9803
GATCCATTNCTATACTCATCAAACTGTAGGCGTTGTAATANTTTATCCGATTTCTCGCT
+
E!3BEH-8'5=,03';$+<6&F!CDC8A&'F/BH9A&6>#$$/96F+04%;*8D@)$C2
@r9804
GGAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCNATTTCCGTATGTCGCCGGA
+
%$?#!!E7&/36%G0)*:7$68:)-B%'@ADGD"-2D</?.%(93&G5&+D6:81$!-$4$6!*/C4<22(!A*3!D<=B65
@r9805
CAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGC
+
H*:=G&3/7>43AGE83,0""D0;=$=DH71,(35+2=F'''H==+)7B*%:$+>&63?GF((A--9C1$@69!"H!7E"!>&C"AC*(E(1D(=
@r9806
NTCNGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCC
+
(#"&+(#%##$%+"(%#)+'+!)!*!%#%!!(#'$"%)%+'(!+*#$)$&*#&+(!%#'
@r9807
CGAGCGCGGCTTTTCCGCGCCAGNGNGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGA
+
?86.:%D30E>H.9'3,"&+AAB-4@$=7(;7-@82?#@')0.F+'>><6%3!!3$$3';/@.?A:"<";%;63"G3@A
@r9808
AGTCCAANNCCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGA
+
(*($)'("))$'+%&#)"!&)$+((%+')$'*&'())!&++#(%"+$!#"(#+)*&(*
@r9809
TATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATACCTTCCGAGCATTTATTAAGCATTTCGNTAT
+
@/FD7?)G%G9,(-A:E:*($3*628D:1B600H<,#CG8,'&1*"D224>+GA%:-6809:1.':G:$FEC33B%E!AF$F4>-DB"&7;.?'A&A*!+:),
@r9810
ACGGTTCCCCTTCCAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAAGCGGTTCGCGACGAGCAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATATATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCNATATG
+
!$$)#('*)"'&&(++%$&%$!'*'$%)$!!%!#&$%+%&+()*""!$#$#"(%+"+(%##&$$*%$'#"+("'#*&$(*(++"&")*%)(*"($'*!'&%"$(*("'&%'!*("%)#%+'##'&"&#+!$'%##&*%"'##"*+%#&&$%)$*"+"'#'(!+)'"*$*&*)*)'
@r9811
CCTGGCTAACCGTGACCAGAACGAAGTGAACGAAANCCGTCGCCAGTGGGTTCTGGCTTTTCGG
+
/81C+#3E,/H6-75(DB1:8C3*H#66H/36>E%4B917B$G:;#954@+;#5"3H<(30@!,
@r9812
GCAGCAATATCTGGGCTTCACTGCCGGGCGCTGTAGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTG
+
<>B;:7G*1)9D3C>1B?3:C'B6#%7>H;.%C:@@-5())B:&B!(*8(70E2019:4B:G$,&(6)@C0.<=
@r9813
NNTAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGNCCCAGCAAAAGGTACACCATACTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATGACTNGGCGATCTCCGCTTAGAATTCATTTCATCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACCCTGGCTTGAAGCTATAAAAAAACTAAGTAGTGANGAAAACTTTTCA
+
'!$#+'*(#%''!))#%+#*&'!'!)'!%!!#$!%!**$'+!)'$*$)#""'+%&&%*%)$"$''!*"'""(#**'%%%+&**(%""$*%'+((#+*($+#&)"$!&!'%+&'&+)*"%'&+&"##'$!#$&#!"+$''#(!"&%$%!*%#+"*)+"*!("$'!+*$*)(&"#''#*'"($$))#+'#+%$%%'&%&)&#((+)&&*#&"##*!%$'$+(%*'$#)(*$)!$*)")('+%"+"$%+&+%*##%$))&+"(&!*!)*(%%)*+)(#%!&$*+&!+"#%+(!''$$%#+!&)%#"+"%$#!!*"%+'+#($+"')&$!!))"#+*%#!"+'+(#++$!
@r9814
CCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCTTCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCNANCCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAA
+
DA;+BF@FHC,:0&1F,E$-.E)+9E4AA88F*G2*,E(&H.>+E<8,C@0+#)13.@E73@=.)D+()'-34!'0#G+<D<)1.@*C-3G$863@FF>B"707<,#-=!8>8G"+<G-0'28#!=C;'*>H91";%3(1=3:">4,BC"!,#<E&.D?#
@r9815
NATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTACGTGCNGGACCGACCGTCGGATAAGACGTG
+
"=&?+*:97.D<"*/D!F#4>(,E&BF0(H,8&'$.8!;-99B>6/=4H4A2338!E7H9/1!"":-$+G0E&9%=>)@-5;5&H>
@r9816
GGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCNAGCCGCAGCACGTTCCTGCATACGACGTGNCTGCGGCTCTACCATATCTCCTATGAGCAA
+
DC7'9#3<4(>E%HA-3<?>$#4#"-<1198!54BA1#CG?(.E6,"")+@2@<!=3/.F5$2D5C=D489F=-@A2$@A5*D149A79EB&-D'51;E5+#57:%E>AF-
@r9817
ACGATGTAANAACGATGAATGCCGGGANTGGNTTCACCCTGCATTCGCTTATCAGAGGTGGTGCTCTCCAGAGTGTGGAACCAAGNTAGCACTCGAACGACGAAGTAAAGAACGCGAAAAANCGGAANAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCNGAAACAGAAAGATAAACTTAAGATTCGAAAAC
+
?#-;#:;:ACF$63<,=H%%B+*,"90D@.:FG=:2;0-G3A@-1>D#80.5C*;A$2.D-:AB>F<*77)(*D:,+H?A1E"28(/'.323#!-#F)4;:>91$H:83AB2$$3-':GC".:;>"3("#8%:A9-G:659..B47:-/G-)7C*,E52?DB5$#;;;+2/-DHFG.1E64>G#)>&12=>HA5
@r9818
AACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGANGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCNGGTATGT
+
F$?&&DCE/)+/E7ECCG;B)-?B9*GD24)D84*+&D67!840A-;&2=($:"?>/>H==F:6',B#,H,7?:>=:0C&H!H8/(0#7,0F-4+;+*9$$&$"(H1"3:C)%!B;%#(=2B<:#)1CC"9B9*9(*3?A*1(/5.(6%8!!(D4!8$2=16'1>=EA+G
@r9819
AAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTAT
+
%9116D01A/*!09=9D'37CF!->?#&!6/21*<BG%$E.+<,,AG$5C
@r9820
ANACNCCGTNNNGGGTTTATTCTGTTATTTATGCCAAAAAT
+
*'*#(%#(&*&!++#""'#!'*#((&")!!*$%*!&$""*&
@r9821
ATNNANCCGGGCGTTACAGCATGGATGTGGAGTATGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCC
+
&('##+'(%)!&$!'#)&("%&$)(!*'%!'&#$+(#))+("#!*'!'&%!&)*(!%'(+!!(!$)!*+#)(&$"*(+(*$!((##
@r9822
CCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGT
+
.3GD+4"'H1!9%(-+"#-4&"-1H*2H,,<."/AEB21>"4F-+F0)H)523E+7"C)'-9%+E>;+).G
@r9823
AGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTATCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCA
+
B-:;G7E$E*.097)F9/3C)=E=?*=5*;=34$A<@0:4492E)E5!G+025,3B.)D6E3=.*1B1$CH0590D*?GB+#C=$F(7C&DA'BEG%;C/>C;:@7F72=29?F0)%8D44&@/E1'5
@r9824
AAAAAAACGCCCGGCGGCAACCGAGCGTTCTNAACAAATCCATATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACCCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGNGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTNCTTGCCATTCTGCGTAAAACCTATGGGTGG
+
&G7?/#;9:8*&:+H+9/"&.(&<?)3==G?C6+;/G2>6248"D%%!3:-A1.?0<2;/%3!8D56-9$C(H..>F6"";4$H?8-!,H30-+?=/!#!0H=C89>3+9(9C014DH$7:#"#A5)(D;DG30$(6A"=1G&B0H4:HEBEA*=<-HB"7&&=7HD6:2&;1F!:"%EC)'G,-!:A((;>?&*822>!BD'5()DD,=G#-5C*2+8;&?#;>GF66?0))#AB15E(6G>497,@7+<</1)7<552;%E3D,3!3775%7.0
@r9825
ATCCGGATACAGGCCTCGCTTCCGGCAATACTCCTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTNTTCCCGGCACCAT
+
6<#6:%"9CBF7"=;*G-6$A&;%8!<G!H:#A*/++)A'G../%0A07)&5+0A:0585::&5:*4HE5@?/6,&,'2/,E1-;4*83>;>?.'(G*;)%(+
@r9826
GCTCGCACNGCATGGGGGAACTGCGACTGGATAGGCTCCGGTC
+
('#$"(%!(*$)+!!&#%*')$**%**+*"(""&#+%$%!'(+
@r9827
GTATGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTNGCGGCGTGACACCATTCACCGTGCCACT
+
D><:%<>E"!%")F1;):&#-,2@"!<B$B!A(!1%.BCHG.<1?+'='6B(.4#@&6(!?!7:4%+*?6E4)'B#.$G&C6;:6C*;5*020&,00*D%?D?
@r9828
AACAGNNNNTNNNANAGTNANNNCANCNNNCCNNNNATAATNNNAAGNNNNNNNNNNNNATCGN
+
##""#$!$!#$!"$!!!!!"!!""""!"!"#!#"#""!$#"!"""!"#"!!""$"!!!##!###
@r9829
TNGNNCGCNGTNCTNGGCNACNGCATNCAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCC
+
&##*&$#"!$*&%&"*(*$%$!!++#%%'#'&#%*''%&&"!$&$&&)')%('!!(!%*$(#!$&*&+##)"("!
@r9830
CCAGCTCCTGCTGGCGGATGACGCANGCACTATGCTCGCAGAGATAAAACACCCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTNTCGCCAAATTTAAGNTACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACGCATAGAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACA
+
,.@-:8&@GH25$742*#>551>G0#3(&.C>99H,?&,/C,$=&G6*0%1D21?*5!=9&"-7H/39(&=99!4;/B/7#19!:2'%"818E1&0*G)$A(H-8H>+:8A$1,(&15+;C>"4!D0E3A5=*5('CEF=:&B;B>$B%FG89;B.6"*=+5#<9.=97!#-#4*=-B:(>3C/+,@1,EC)D4''B6,
@r9831
CGCACCGGTCGCCACCGCCAGCNAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGCAGTCCTTCACCTGCCCCCCCTGTTGCAGCTGGATCGGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTNAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAANTCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAA
+
1!-56B#-F#E#"%!(5';@7E7'>$-!,+<2?3FEF,<=)EG);;@H>G%!'6#1+(")>@(HC.>)4G88C,4815#$"61!A$&:%DC#>30+2$GG*E5?75#A4,6C1:)$,9!D+8!1,4&66!5&45C7&"=81F>F+;-:>B)-H$B?1:$=9%2G*8@1?-"-'-5"9%A3?2&&))/<)-9B!+H@7,$*!$<D"C-3)59,D1E;B?&H%=8HHE6(;G.0)10A91%,'(19<H4'A=!G(5,>E'HE>!D-?GB--#@732)?#)H3$B!09ED&*+(#0B!;/%0@#'.CB@(4/43=%
@r9832
AGCTTCACGCTGGCGTGGATGCCCGGAGAGCACGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGT
+
*6=-).C=??D)@+2!836A4%/D9(?HD)#C3)/7E9B%F@"(A=3'H*0(D+2G'(;&?C=3D1./'5CCG%=A&+6=G&?A37:"';A#;G$')?.3'&CG(1B/$B8!<%C/)2+&!%E'#<-D!/=%/(4BH/$>1$C&4.,A87-G6--%+D-7"F5><FA
@r9833
CTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCAC
+
2&!943<(C%)7D!*&G>:7H11<5;8'B->.;G$5H:A!=&!4*A$8%2C,/.2)BEC+=!A7C$@(('/:-"#F4C:*#+*B*:&B+<56@4C?@5G,,4::BG-%(@A?.?+!'":H
@r9834
CTGTCGCCGGANACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGNGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAA
+
,</",A9:5B-CE$3)&"72>*@::AAD)A*>+;B%B!3>;-="72$H9E7&$-?":0=:7%,9,<-A>$37B8*$C"+1'H;%=A0=F*8F0-)H;"6,1&&8))!;&5C0D0D'4&!,2
@r9835
GTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGG
+
*.%&!%112?,HE4$;E4&@@)$=5E>@H>D;0CE-*%HE5@
@r9836
GCTTCAAGCGCAAGACGGGCCTTTTCACGATCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTG
+
C!E,6E:%65!=?57#$'EAF?'B%1,B?"(%+4$1/?+199!;;H0!!7*!80;#:<="6$)4"7H,68F1E7=;GGG'-!$&C5?7C4$BF@DA#-<-1$.
@r9837
NCCNCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGG
+
%)!+*&#+'&$"$%!*+!((")(('&&*%**%#(*#('#+$&)!"""+&)")#%!%$$)**&!#)%!)'#""%)"((%($&)("!!''$))
@r9838
CNGATANCGNNACGCTCTGTACCGAATGCCTGTATAAGCTCTAATNGCTCCGCAAATTCGC
+
%''#%$!'(!(*&(!+'"%*$####"&)#"+&%#+%'(#)!'((##()%*+)*$"!%*)%*
@r9839
AGCCACGCATCCAGGTCTGANNCNGGCACCTGAGCAGNCAGNAAAACTTCGATATG
+
&"'&(*&*'*'%''!$)&'*!!%%+('(!"'+#$#$')*''!%+#$%%('#''!%$
@r9840
AATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCTTGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAANGTGCGAGAAATGACTCATACCGTGC
+
#08??1(B-;<=G5*::,B)=C$=FF:>+7E56DB+(/!B@F=7>?'.>&;E?:8:D,2>HD)><=>F'8-?868.#3H:.>=>BH/G.0*3809=!.:@(2$:=F"3A!(0C;>CG!,HF.2A9.D+*'(!8("?1,A"'!5+3B!9<G+(5C?99HDB<)!'>><+B>)1D%-+>#8!<+4A<B=+8&,:/#!5'(FH3D2;9
@r9841
CNGGCATAAGTCGGACACCATGGCATCACAGTATCGTGAT
+
07!8,0/:2&0A:"9B872:>?57G(EA+(4$-39#7<,3
@r9842
CTGCGCTGGANCGTCTGATGCAGGGGGCACCGGCCCCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTT
+
>0+6@#6(11&9&60GG*)('.B"'?;F571'+,5"*G?F8-&E=5;3$#G$-@-===$0+D97*22'85%=#GF>AA=F>#"65/E#/8(59-F8/91902E"?5'8>>;!0(6#'*/#,FB?/C5E
@r9843
NTCCCGNGAACTNGAGNAAGTNACNAATGAATNAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCA
+
#)(&!&#%('%*%!&'!*$(&'#))%(&#%%*)+*%+#"#")!!*'*!'"((('&!"*&*#%(*!*%*$!'++#'$()+$)"!'!"(*#
@r9844
CTGATGTNCTGGAGATCGANTTTCAAAGGTTAGTTTGTTCATGACTTCCNTCTCCCTAAAAAGGCCTGCTACGGCTGATTACCANCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACTAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGG
+
?28%8(!9=1C24:-/".>2.;<E;CBF39B@:;3)02=?1C6>:1)?<C67A'-6E!D'-!(#H8!AH-0:1;02@)=@A1+E<),&:<B-C$C;(B*:#HHA'):@,;04E6!:%40;8*B/F1G&?@54G'6G2.A!&!$@3>*12?GBG*882F$0'1G(.8">A5$4$:<+@3'8B;).0>A@D,H!)03$2(#8!&@(>2&&/B&"@35.%-80>%:$A8F
@r9845
CTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAANCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGCGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTNCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCA
+
FBC+C7#2FE@H4;"'(.6'3/*/!03/9(,=88A;-,>+H;H'*'3>385D3G?F,!'H8A7B5*""%)(3F0H299$BFH2?-H0=A$FF;.@=F)@$/"-!,?=.@F?:&?51'H7&EA'057-)$H,6;!'$>HFE&3)46"&?;*6'$@B"88=54*(+!->02H*9AG%3+D"=&EH,0*E(D2/;3>B8;6#=6:)</#G&2%32.'%F9!/=G1.!-)(87"G40C%8E8/:'0*8.:A'4.9G#5>=4"6802*8-G;B
@r9846
CTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAA
+
93B19+8@!&DC?F>):5>"$&1%)=HHA1+95@('?@9;3#F-,C56'7-@1$0-&4F*+ECA%30:2@E<<A))EGF;H'6#*7%4B=B%$$44):!F4*6+:A,2"5:,C50#?3!4;+A&.'!?-0%H@D=?4BC<"9(2=+:=;E010=E0?,(8:"9)8+2(#E3@.8H-7H)'!F$
@r9847
TGGGCCTGCTTAGGTGACGTCTCTCGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGNAAGTGTGTGTTTACCGCAGCATTAAAGCAGCACGATGTTGTTCCT
+
11A9!4&:6(2=69E?@=&2!,,C@H@6>/B<D"DB'5=0#C8D,,D?0D*#36.8,6,/0A857*&32;F$3B7%(>@!<70>91C$1'#;?68<A1-,',:*7:B8:@
@r9848
GCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCANGCCCTGTATCAGGACATGG
+
1*+4(4A441:?2@C'8D%$+;*(,B&)-D6=#588.6'",F'?+",7G<GG7)+9?=!#6(79&>=+H.(!D8/H"#E7-9C?>($9@<#A$/H3&)>!#7:5E,"47%#2C2=E(97.G+,H=1C."+?;5%21C>9;B?C6A*2&8C/356G
@r9849
TATCGAAGCGGAGNACATCAACGACTGCTACGACCACTNGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAAT
+
<A*/<,5?7G%7+A?E*2BE+E"#2?(?D9G/<$F212EH96=,06@(ED(/H);@@(8<6FC6"C*<!8CA</."G#$-&:>H1>0
@r9850
NTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATNGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGTCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAA
+
!;!<2;)(11B>83D;%C'F7)'049)6'*D6+-$'5&.$?<9""&"+F'42:</@59-4H?$?&7G5+"$.A1.,!E8+CA5E=9-99**HE###6?->(5?6*G.//1611&543:&6=!.FA-5C@*)D.F@,:?C3.@!G6?/@+H&
@r9851
GCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCC
+
@76BC61*#>/(%B?1#?C'1!0$D1"*.-8?C%E*+-1(73
@r9852
CTGCCGTTAACCGTCGCCGCTGAAAGGAGGATGTNTGGCCATAAAAGGTCTTGAGCAGNCCG
+
G1H=*FAH$6G@34'4"6*)5,64;0;5#9!C%4,2+(>E(D5E7%:6A,DHB:9!H:>B1#
@r9853
GCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGNAAGAAGGC
+
+!(%)*"#(+**)&'!))"#!#*')*#")$%+&$#$#(+%"!""'!*+*(%&"%''#%'!$&!)"!"*"%'#%)##'$)%))++%)#")$&'+)%%#('%!*)"+$%))"(&!'*!')&&(*&$&&(%$*"#))#))%""+$'"$)$!#$##&!#*)"!%
@r9854
CGTTTTTACATCGTCTTCGCGCTGGTGTAGCCATCATCTTCTTNCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACC
+
9:&H#HC!%2&F+F6F=>6-A<F8</:;!9C#:;3-(24$<&3G?E90(DG9=/@*-(D7A/E6D&5417E#1@AG-E"'&HC;!;<@&,!54'*27#(/E"H;0A*E-(H7";4>-9.>#?7=F#1G#;)#8')H7&>B<D4&35H&HG58F0G&%B904?1D7'AD:.96?':HCF*F1)@:9;D=4AE<++FCE*
@r9855
GCTCACGGTCAAAGTTAACCATCTNTGCGGCGATGTTTNTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGNCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGTACCTCGAGTGGGGTCCACTTATCNCGGAGTTTGGCCGGG
+
D*,7?"8<<%=-%#,A("39$&8!"D*2:>C!A6-F5G08AB-6;)-GA(,&)A:C('B-00F+&*HD&D5!@#'/&+<E='#(6%1$)7:9%;6(C+DG:$-,>1#E@<:A1+1C,5,25:6+6"G8<%,"E&1(10>H<?'#9@;+AD/===BB@",C'&D+8#18*B
@r9856
CACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTC
+
.,,E(0<G)4=C'CG=<"4.=$)%$BA!H"3,:#8759>*DD%=8:F'7'"&(*A!*A*A(HG1B6%2$<2>;'*,/0DB?:&,:B("D%,5E*#>E%3CA"?+G"3G66//.,#'!6$5$((
@r9857
GTTNATGNTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTNAGGCGCTCCTGATACGTAACCTTGTCGCCNAGTGCAGCCAGCTGGCGTTNGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCNTTCCACAAATCCCGGCGCNGCTGGCTNAT
+
&'!#(*#"+'#%""%+%'&)'"$&((("#+!%%!)!)+(!&))#"&&)*%)*$%$++%"#%((*)#*'**(&"!!$%*(!'%((%"""'*$%+$$%"%)$'%"))"!+)'!!(*"+""%"%')'#+&%$%'+&"#+$'*!""(##*)!%#'+*"+&($)+*')"+**!(&)"$()'&%($#%&''+""*"&$)($+*"#!%!&*$!)&)'''$'')$##"#%("!(
@r9858
TTTCTTTGCTCGTCATAAACATCCCTTACACTGGTNTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGANCCTCCTCAC
+
8?5$<C<)'.>G'A7+5*DF;0@(#<5F0)5F6F$7:/+;+#.A)'!0*6HH%95H,F(.6G!-/&/?G&0A#E#02;D!0D%C$":;=<GA6&&;$A5B?.@+B07G2-&E>7(.>:(("E:8FD6-=(3#>+#:;.:AAF897(!F7#8+>&7.C)%5D!F#*G$#G'B;.;=*9-$9@(&4H#+):"(41*E<,-+@(04','++/@&%D%)D'=/,4-C<-G2136#2$*/C8&+B&F+1)"
@r9859
AAGATTTTTTCAGAGNGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTT
+
>G*B:E/E6C%<%<'GD2H@.#28GFA,6==56'4+)5%((:0H"-?:)@%4%,?5=+08-9?>69$&A>'0E@.,
@r9860
TCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCT
+
FB;5&,2"#/-9)11)=B?%C3=1*7:?)8>9'B5EBH"1/,)?<@(,C'B.;(336
@r9861
AAGTTGTGGCTTGGNTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGT
+
'&D$B/>1)89)*/2D#!!"G*C#B9F79G"D(<9<#7(0"0?B'&9!DCD3>?(&;'1*2$0
@r9862
NATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTATTAAGTTACTCTCTATTACATACNNTTTCCATCTAAAAATTAGTAGTATTGAACTTAAC
+
&8C;+:=0<8=&"EC5(*.,G&=G>0/56H0EA%5$?B3,ED,/)?0G.>,3;:%>D<18*.;!<6;9>8:B*:0/)F,G)CDG4+"9,C3#EE!-%2=H?$@/1&
@r9863
GCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGAATGTCGCAGCCCGGATTCNAATGC
+
DC9G0)"463GA$B?A/H).&8?0"3(>.5%1D%&:503+"-6HEB4A.*F==*-4$1,C3D.1)!3.A&'@HC&(27#6>,D.=>GHF+47#$+FH6!!AA//+G+C/C0-8.D=GAC$B6+@.
@r9864
NTGGCGATCTGCACGGATGCTACACGAACCGGATGAACAAACTGGATACGATTGGATTCGACAACAAATAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATGGCTTATCAGAGCGTGGAAACGTTAAT
+
!B3HG+E0CE)4B46D&?8-D/G(F:5G90:87<'&9*7/9"A3-B<+0?976>.(*&,A6B(G/,8&1)"2?7?-"+D%=?=28.>9/%,;G:1+2'%>#7)86$&8-=EBH@-3BG!5>/<F:()1%;%-BE?>2!$C:./$!-#>$33'G>)#9/":H5=E+6.!-4>(;('.;/:9/34%'F;&E/,'(23.?&>(B:22<C&)A..@+F'8(/84@
@r9865
NAACTGATAGNAAAAGTCCAGGCTACTGTGTTTAGTAATCAGATTNGTTCGTGACCGATATGCACGGGCAA
+
(($('%$(')+(%'&$""+&+)!!!!+&+)'"$&$!$!(#&()$"()$&))!"&"$*"*#"%$+!%")&%!
@r9866
TTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCANACTGACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGNTCTGACCGA
+
(&%%+$"))%))!"&*#($+##%)%#++#(**+&((+)&+*!+#'&'#!"#!$*&!!*'))%$#&&!)'&&&'(#"%%!(*#('(!*!'%$#&#$"*)*+$&(("&(*"+%!#$)"($$!*!)+&!*&+)$$'("
@r9867
ATCCCTTCACCACGGAGAAAGTCTTATCTCNCACAAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGA
+
1D""7H/):<2*B67B?@4%*,B=A5D::BA3."79*D.%AF??.9$%1F#FD.%,4<.=D0-##80@&>2GE%G*<F7";=+:<H.=5'.322(6!#5(DDD&HC02,@G6F3.G.6D%@B4<B5-)6,@5F=@F=-=@-=05>C8!
@r9868
ATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACN
+
<33"=%C1!C!F!(?B%;2'8E,,EA+3<@(8*9*);:H"!"&;(DG3+=!$F-$
@r9869
CACTGGATGATATGGGCGCGGATAGCACATGCAGACGTAACCAATATTCGA
+
EFD1F47G4B/9*$GD:@@<!F%.H?!6H/-C@25494D$,#E2!A%7+*"
@r9870
AGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCA
+
6"'5:BC*'>E;..,-)0/9,H!2+>%$.$C2G@5&=%=C0$:,C3
@r9871
CGCCGGTGCTGGACACTNAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTGGTGAGCAGGAGCAGANTCCGCCGGAGGCAT
+
2E%?./;63">G;5+D%(G:*"!6@A,('CD.)7C+-1+58??672H'!+201H1(55;+%.H$B?BED9#(-2-+F1'>)??3,$,4!A<#1
@r9872
CNNTTGCCTGACNGATATCANCACGATCAATCATAGGTAAAGCGNCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGG
+
(($+))*'+'%+"$&+$$%*%"#)""&+"%!&%#%*#))+%$'##+$'"*("')"$"*%'&$$)(*)%#'')&&(&(!&$+$*(!((+!%%
@r9873
GGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAA
+
>%6H:=@#<F071$19!?4H%,A22G<C?CF0),0(8(F$61
@r9874
TTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTANGACTGGAAAGCATCAATAGAA
+
H=;78!"++>$AC4?#DA=D/;0#E:##?;0&0E5,?2&1>9=*7)'0;FD%91*D,/*$C)1.%H&>G*8CFFH8"@
@r9875
CAAACTCCTTCGTGTATTTNGCATCGAGCGCNGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCATTCNCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCNGACGATGATGCAGATAACCAGAGNGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTGACCGTTCCGCCNGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACTNCAGCGCCCGGCAGTGAAGCCCA
+
!'&#''+)&#!&(+!$#(*&$*'')!$$"(&#(*"'!)#"+#%#+&($*!'*)*&+)**'++%!#)(*)"%)#)&('*%"(&'"+!#+'%+''!!$"*+'#*%!*&"%("#+$(!(#")((##""+*$&%&*&&)!%"$%%%$!!*'($'$!%$*(!#"+++$"#"!''*)'$)#')++#*!#'('*&(#(""*#"!"%+!#$#)'+")!($(")!#+!+('!"+!+$&)'!)"#%*&#%)'+'%(!!!'")$+#($$$)%*'&$%&'+(&$+'$+*#&('")$"'(*#!+'(($%%#%$$$'*)$'%!!)*"(!*#%(
@r9876
CNCTTTTNNCTGTCTCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCNGCAGTCAGCTGCTGCGCTTCGNTCAGGTCAAAAATATCCGGGTTATTCGGCAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTCAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATT
+
$&&$*'"#'(+*&&+%'#"%#&$&*"%"+)!&"&$'%#%*%+%#*"*(+$#"+')&)(+!*'#%""#++$#!""!")(**%&##!(#)(!*'$"#!)*(%&+"+++&$**$"('#()%$(&'+!$%*)*$!*)''*(*"++"%++'*($*)((%($%(&+&#$+'($)++(#'&&)((*"'$&(%)+)%&"+*#(%(%'(*#%*
@r9877
GCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGC
+
F?/6=E4":@"A?/7;-0$!02*.&@0-@1*(&%<7:,B-@)8'
@r9878
CGGGAATGAAGTTNTCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGA
+
+$*')8@<;F=.'@:%#0*9?5.+84A.EB/;5AD-&)2.8EC7=1!82F6
@r9879
AAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGA
+
FB:&3',73G%EF63@70@80.<!$=523<.7..=/%53>$B$D0"AG5'CC)C-2?>=89'H:GE$*D#<:F",;4GH6;A7'@5-A)G%E9>G>2
@r9880
NTTATATGGATCATAGCTGGCAACTAATTCAGACCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGGAAAAGTTTTGTTCAACACACCAAGCTCAATC
+
%B-D3%;8'7A14>B>E9>,A58AHAA@'.?;;?@,=*<?:'0@;,<@G%/;<B+7.C8E/,,E&.?C(B#0!C>D%9/DAB*0DBF6D,&>7(,A'8+E"!"10%(+/=8)#77
@r9881
CAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGNCTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGAT
+
E"8E-70%H>886HH)+"'@0<&AD4D-9<*F(G4H8B6C@5?$>B9A1>"=B>/C53><&F6H8C6/B8>3>'4CD2?++3C4&->H&+'0#@9,<>+/>6!D0G3,,=,+;)=$8C,7('),:,:/":+H0>!;>.:?H<C-.;<3D&$46:3)E'1?
@r9882
CTCAGCGCACTGGTTAAGGCGGGGGTAAGCNGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGNCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAG
+
E23F>D,/&6,0*E-E6A)':52"=,!F!.=&$*@)>%A+:+9:*1),#*%13#"H,<D;(*H&,295#;.;B&?;+1DD;?(1EC2#H%50,C?'CC?((E4=C*+1B?1;.6-*5'34@1<&+>
@r9883
GCCATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCCGGTTCGTGTAGCATCNGTGCAGATCGCCAA
+
E#%9%6:*DF-5<1+-D$-%AEAC)#F0@6%7,:.<:B5()+,A:?9E:E7"9-'6#E&:E**%:3G8*,#,4)B>&A>5D/;/+>)9*!690:-&B9/&CB@*8:33<B5-4:))8(G(62"6+/!&,#-*:/9;0CC;C*H34*A*AG!E:F(B(B,;?&)"91D%D9FG+&2?A47"3A/B=1=>7DE@0-045
@r9884
CGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGNGCAGTGACACTGCGCTGG
+
=!A6<;?8'5C68)DB0=(/2"+$8?/@FF,6;=8D$$$5*'>6#+3(H3>/>D.).(
@r9885
CCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTAT
+
!+*#$'+&%$$(+%&!*&'()%&)+*'&!""+#)'&'$#)***()*#$")$'"+($*%&'+!#)%&')"(*)&$*"#
@r9886
CCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCG
+
!;*'A+'+;C"2+&?%9%?52@'=A>8=-F?)*.@G78=5'<E<%2*91D?
@r9887
GCCTTACGCTGTGTNGTCAGGTACGCATAACAGGTGATGCGCNGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGT
+
1.3F1?1@8,<4++D)E/**4/?FF&G'EDD7+:?8"H9D:G%G+A;E9//+'G%4#G'!$80&B=(2-,!<<?-'1D+
@r9888
GTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGA
+
H?A;:)0A1E=7=>4$AG3778C"D2BD!+1H0'(9E&.:%@"!5"!$8#=;&)1"-@#G61%67+%=9@5',5*'B4G6'#*!
@r9889
NATNCAGCGGTNTCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGC
+
$'#!*+%*%&**+#$+(+'*"&"(%"*!"$)('+'$"+#'&&((*)(!"%!%"$"+%+!)&)#*&%"+*+&#&(+
@r9890
ATTAATGAATANGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGNTATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAAC
+
$76>A#1#8B+:'D25-!2@:?$AA&F/10&>0#-$&5+-3:E<5#;*$68/5D9*A5/E>9('1#?9778D?>5F'3$(5H4@2:B+"3+8>%H-@&E'41D25G/:4))@)9+"F)#+;2F"+3$9#E86?79#9D<,17FG,-!*#F4C30$:HDH?=;0:#*8).H5F#9"&);60+$(?6(H@E.!'#$&+5,E'$D'F?48:C*8)H3+9$$7;,&-9:E.3.%#<>?$9-F28-??*4-FD+>C0'/!&.1--G$
@r9891
CCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTNACACGAAGGTCAATGCGGCGACCAAATCGTTGTAAA
+
)>3/%7=%8/0E##>.()?>H>A%&1FA*&<0B6@H&//C<'(>H=%B@EC&5$84A&=%>/(4B(#;%D"9#E?8E8'>,?4@5E5,%643@&-+??5>/35A*>#39#A-
@r9892
GTCCNTCCCCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGNATATNAAAGTAATAATCATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTA
+
($$$((")'+#$$"#(*$"!*"%%!+++(*%%)#+%%&'$($!&#&*!&*!'*&)))&'#')"((""!$%%+*$*"("%)#!!)$#+%&#&'#""'(('!#*!+($!$'*#%+!$)&&%&+(#("+%%'&%)!!%%*&%#
@r9893
CAGATTTTCTGNNNTNGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGN
+
&%$""#'(#&("%"$#)+%")()#(+"+*!!"!#"*""$*)*!#"$""$)'(*+&#"!$!!+%%)")$!&*!$"!')'!*!+$''#%+)&#
@r9894
TAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCC
+
66677B/E&(-H$G2E!-G4(<'#%*@<!HA%,(43.''3,!1B11B+;>F7C+1")D"##5E/,4#;#FB'C":#<2!&,E#*>5;:3A);H95+)H:$2544>.4D+?C/45'!3H<E%*5E'<+4*)
@r9895
AATGTGCCAATCGCGGGGGGTTTTCGTTCAGGANTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATCCACAAAC
+
54CD:3,<5,A&4<C?/7%F&>;@'+8B!#EC'F@B*)F$5$=#.8#+7/3,09CH-)+$9;C)#<6C>$A':9#*3:1@G#.H1C-0:)@8;
@r9896
TGGACATGGATACCCNGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGCAGACTCGCGGTGC
+
%*+'$%!''+(!!#+*!'**"'&%#&"%*+'*!($$%#&'$$)+'("&&!+"()%&'!&&+)()+%%!))(*$('$#%()()&&*###"
@r9897
GATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGC
+
&4!595,+3!'.)B176??=##G:E6#H8'&>H.H7%&B?A2#!=B*"';%D02>F@-'.@=363,;"FG=G%-41&6F#%*:<!!H?8H
@r9898
GTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTTCAGGTATACAGATTAATCC
+
H4G@.)''7(=<%.C7'DE+A%+.C<)"HD!G2C%-@?-,2A-6;1D/6"@*(HD%G667F2#&@+A&3/(**=259@@?<27F:$+H?*8*E3A%@-@/%*./-+=C#7&A+&D!63A)'=G<DG818C*B1/1<43C->!@>&&:#(
@r9899
GGTTAACGCAGGAATGCGCGTAGCCCATCGGCAGAATCGACCNTTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTANCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGAAGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCNAACGCGCACTACTGGCTGGTTACCAACCTGT
+
;)FC(0A!FC7G1()8F.&%&4E@7,B@-F8H6C,7B:;B!A+"3/7!F<D#-.).?E*"//?&@+HD14B!(;;>*1:C@..05;4'3FG.*+FE=<,/D<),%$&F@9=!F(.D,'5"DCD0!&3G.A;%2/1#$D(<8A"%%7:51:/F108;<+H+)!.FB0>;#41?>?2/6.A'@!*E71,ED*($7#*7145.75!(@!D:36*A"7"62E15H3!1%%/&!3
@r9900
GGTCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTACATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGNCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACNTCCTGAGGATGCTCTTCGAACTCTTCAAANTCTTCNTCCATATATCACCTTAAGTAGTGGATTGCGGTAGTAAANATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAG
+
":H12H&4A0<-CCC.:'$G,4:+CGG,.3*66F,,$A0.G;$)8""0:!=$&,B!8&!587#/EE??C8?D1'5*?%4/$%B9$%*+6%8A/:'3,.>#0)4+/)C+,FD'&"6+D'G@=+C9#;FD<3(&!;!D62/&=G&=65'79C?=#.@G?!H3&&B,!G3$#&B#,2%>5B4>FB!=H>E+%4F+9<":73?3!.G9+3EFC#D7&>4HE7"785-0#:?.908E<(>CB+1:)8E+69/*2+=8>7><0%3.+#);/C?$&(0:34C(:#&!5&8.;A,G)1''.&GF2B-7!GGC2+#@0;=;
@r9901
GCTAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCA
+
?44.G:?90GB&3&C-0@2..3488<6'@'6>,C:BFF!,&<5/@.88)<G8;*6)6469%7B2*&539/<;+
@r9902
ACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTNTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGG
+
6+?;++4*&B'C+9@!!*0(,G-EF:"15#.C>#01D'CE7*B26)EBA5H..8:1C=*E,1"=,%E:*D!1):@%8E9;.2B8F?.#&C2,E);!E)(:&);D,:=!!).5,.A$>H%=.,F!G*@).B?@%/.,890(/?)<4A3-,'AA<F)8:-F+F4F>D>?HA5+3B2>?)!>A&?=)D69>E0);4FG?+>5$A.C.(2*E!
@r9903
AAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGANCNTTTTGCG
+
+)"4+%D-@6#:E9"",)D6B!5C##FDG#B8-,*'2+6*HH,105#&,,F2D59
@r9904
NGAACGNTNGTCCGGCGTNAGGTTTACGCCCGTTTTCTGGATG
+
!)()'#%#"+$"'#+#&*&!+!#$$$%$)($)#%($"*&"$+&
@r9905
TTTTCGTTNTGCTCATTACAGAAAAAATAACTATCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGT
+
#)6AG.,>F(9?1!:B+?3%G+#5GF")262$::)*A=.H4*>."(CE+H,&B>98),G74>@7>0%"*)/:<F>&(#EG/,2(1'C8<"!7+0//.D26ECB,/!0/8);&B3E6-0@C<G!@)9<H(;=-G;;4C7
@r9906
TAATCTCTNNANGTTGAGAATCACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGCCGA
+
(''*%*"!!%'#*)('+)'&+(!&"%!(+'%%"))()("'+"&$%)+'+$"*!&#)*%$
@r9907
GCGCTTACCCCAACCAACANGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCNCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGACTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGANTCGCACTTACGGCCAA
+
B$7:;('/61G8#:1<8",+)D),&4&E3%+,9%AB,A"71"G>2"9"+E&324?&;4#")%-+'3441?3D%E##&&6.&()6"<,(7.);A?2&G!#?9F=36A,H/<=9DB218*@+G<"91)7&G,9'E(88<DDCE2!E:C$&*-1CB:1F6.=C!&4H$95.!-DG*F5//@:=3;&G7+%.-;1@A&A*6G6)
@r9908
TACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGACATCCGCAGAATCTGGCGGACCCG
+
<31+-')"H2G@((;*:8&!.1=97-6+GH.=.=C)@*07?(9=5/(?F!)7@6#"F/%+H481=8,=(9F092E1B/1$)."'":H0:>@4+4:5
@r9909
NACACAGCTCCCNGCGTTTCGTCAGAAACTGAGCGACGNCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGA
+
%.8</ACDCHH-'C=*!40?=+>*""CG8G>E'7..A$"D@A6?=6*8:/BA>=B*G&<79;=..G)BD(H04H.0G5C;<!GG)@=;98B$@3B5?2?+B%3#*CF
@r9910
GTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCG
+
>E%#)F'?52F:!.+'4D'*@*A&H7%&209G4E'B-@'4$9E(1&
@r9911
GCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTAC
+
3"<./3$?-8&+!:F,CF>#7</)=<#7.--6C:A,19A',3";#+%D2-9G"+@
@r9912
AAANATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCAT
+
%*!*')+(%*'"%$%)*(#!(+%#"++"*")$$('#)%#)#$*!+&#&%&('%)!#
@r9913
NNGNAACATTNCGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGNCGTTGTTCGGGTCACTCCAGTTCACCTCAANGGCATTNTGGCGGTCCTTCAGGGCGCTGAAG
+
)#*$$)#***(+)$$(+%+$#*+($)&*)&*%$("(#(#**+%$%$""$#"()$#"&"#("($#)+!$#'&)!&)&('**)&&)$**$!!!*(&"(!**'"$'#)'&##!+$("&!*(%'!&#+'!#($&+
@r9914
GACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCNACGAATTTTCGCCGCCCCATAAANTACACCCACGACTCGTTCGCACTGGCCCGNGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACA
+
%$+&"*!&(+%!%#$)+*+"'$%(+"(%!($%!!%"$*!(**"'&#'')#!$!#&&"#""'+%$"$%*!%"$"!$*+"$*))*&"''%'"#%!)&$($'$##+)"))!*)""$*&+(+&!%#!'!'&(+%(##+&)+((+#*&)(('##)*($*(("&"+''+&($'$)'$%!!"*%*!$$(&%(&)#%$$"*!"%*$#')"'**(+'#*'($$'
@r9915
CAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATCCGCAGCCTCTGCCTTAATCAGCATCTCC
+
HFF>%,!!A7,9=*=D!+!1CCF66076='F&''H*:FE*2A"AA##1C8*FE,=D51.32-+#FE0*BC)+BA+)B
@r9916
TCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCT
+
H3/&%5),>5093*1"/"#,&%@59/$>2=@<&&'=G*B@!F02
@r9917
NATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCG
+
*EEA(6#@5;26/57D&H+$0H)A?EGB''>G#G4<<-C)'-<42H?($9;4$
@r9918
TGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGC
+
<D09?35CC)'<6,5-$257BG%BGE!461,$#8D'+6'/&/?!6>#
@r9919
NAAGTNGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTANAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCT
+
!;<!0"7)2?FG4%#11:B)%-;=1'#G3<06-C')&2.FDFB9.H%$25/>&7%,DG2<:GC6=G7%!D0/GE&6D<2EHF3!C"$7D#1A..3'/7?30;C.
@r9920
TTGTGCTGGNGGCTGCCTCCCTTGCCGTANNNTTCTTTACCGCCNGAGCCACCCTTGC
+
$#!))%"&#!)&%'(&)"&''#(&(()('"&!*+*'#%#)"")$'('"$%%(*)#)%'
@r9921
GTTTTNNNTGCTNACAATNNTTGCATGAGTTGCCCATCGATATGGGCAACTCTATCTGCACTGCTTATTAATATACTTCTGCG
+
*'"&!#(")&&"')&*)'#+$#%"%''#()$$%"%%*#*(#&)*&)#%&&+%&!%*)"+%%"'%*)'&((#+%!$"!$$)'+)
@r9922
GGATAACTTCATTCNCGTCCGGGCCAAAGCNGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGNCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCG
+
E02F=%;000.=:?$5&7(%CD99'#)+1G<1+9C(:E!)8@(#$>E5)0,'D(/,%36#4=B*2A3%B@3-C<?E*4H#&A*5184:+/'H/'!;@/-&*(09%0+C%/=549C3."F3!/*'"4*9!:=6.>C.F2
@r9923
TATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAGAA
+
*70%$$B.#,,$6331HC9>3:9)*F'0.+?52H&@D213>@7H:)G7.%#
@r9924
GCGAAGTCGAGAAGGTCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTNCGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTGGCTCTATTTAATT
+
A!!)C';/21H24C'30"96&B>;."4B-DB'$+<8C38:>6HF?(G?>*D#1;1($;%-,!?+E3#.<>F;.'C9%%%7:;4$=$!-F08#D2('#&0B0>3''%!;%H.->-!0161*A:992&B-1G#&&%1$"C/H@EH)'H0&=":$2D@7-B6,2611.*("&EB9!(C*4A09'=0F*#&<8$0@B$276*4D;,1%75?"&9/6"C'9BF%.C.FE700E02@
@r9925
GCCGTAAGTCTTGATCTCCTTACCTCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATAT
+
.F./C3-,7-G/G-+3;-.+!!G>%4D7#="3*A4';59+)!3;<#0A?0-3=-<(1/B7'=+7?G:E6+
@r9926
AAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTG
+
BB%@34&D6"DE5<G#)H8&@#5)+76H"1C%C;=!$H6$/@AD#3076H-9
@r9927
CTNACCACCTCGCCCACGGAGGCAANTTCTCAGGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTNGTGAATAATGCCCCTGAACAGACAGAGGAC
+
:+H(8.?D")=!367,'661,7'E(!;##(=H)-:>*=CF-$D?C'18#5G%2@-H;!;=*@:769:<D3-.59?/5B*5@=42%5)F+$,(CG+:!,FG01@DC+03
@r9928
GGNNANNNANTTCGCCTAGAGAATTCTCTGACNAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTC
+
&&(')$"!#+"$('*$)*))')()+&!(!*'%'+!+!&*%++)%'"!+*$'%%()&#+"+(++)(%'
@r9929
GGGGTAAAACCGTCTATGACGTGGCTTCCGGCGACGCGTTATTTATTTCTNAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAG
+
79(9;+#C))->,98?/<F<%(:E%<@=!'G@586/G!=5A69";:0":$*G$:.A:>2G/2:CB<&-7C8(&#?1*%4/"3H0D@D!:4B402B"
@r9930
CGTCAGGTGACGCGTCACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTA
+
:*"*G%0.3$"&G!,+%!5C%3<(?(-=3E7&G0HG#@&3*1H1!F'#!@<#5)8&45!.7=(>
@r9931
GTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAAATTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGNGAAACACNGCCCTTTCA
+
A,'H?$?-4(/5..H$8225#F!*<?$$4#')%;FB6'->8G/!!8>6E#4!2:$G7$)3$,9@245*'=)5%'B.+0?8+*C1E<00$$B9!,1B<13$-/-@/86
@r9932
AAACTGGTANATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTNTTNAA
+
?//>$CH9E;6:-1>(>91/,-CEG&B8(#0:=37E$"5949DGF?"FB5=9).G74<.C93==1.',,27F@"F#F&D?>@'&+
@r9933
ATAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACNTTCTC
+
.)4AF*5#A!C05!EE9+7%@?2'&88.==?7,@)'84D1'@DD3!C*F+-D'?C!1'7.;@!//-!EC<1G;=&CHDCD1%AF?(
@r9934
CAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTATTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGNTTCGTNCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAGCTGGTAATACGCCGTTCGCCAGACCTTACCTTCGATAACCANAAGACCTGCCCGTGCCATTTTAGCCGCGGCCTGATTTAGGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGNNCACAGAAGCTATTNTGCGTC
+
0'"D&6B+0EBFBA;E/-+E9=!A9A46B"@'(=):6''9C$@.G/*01@BB2G$3-@1>7";G!F=F"<?3E3GG65D<D$5/,$%?G$#2.-%,9861)$.EC8/0DBD9/A'C+=/HF14'15C#@H&%*B#"%%&/=;EA"2/%C(FB(E:;'+9D,)1!<G?784BFB>+$=HDH;%!()H#EGD20'*$/DG3H425B4C<,953<,6B;C,54$&#*F%BFG5C9+F&:=-F&)5C?A<>(0(0G;4(4+12E6'#HD#"D,4'<8!*5E,>1/:.><.8=*0/@/A
@r9935
GCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGNTTCGTGGTAAG
+
%++*&!!%*'*')%*(!#'**&+!)!$%&$!$+$#!()!&(##!+'#$
@r9936
ACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGGTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAATCAGTTGCATCAGTCACAAGGGCCG
+
9@@49'*'+C9"F,399CHG;D59787:+/6@71%%?"%B8F85.58HE%)+B:%235/B.*&1.8+2'>0A0B,;$C>BC/0"-H*,C)HG*@84+62,)H82%:1"228%?3,/,A:*)87"D&"0->62016(6/>58G>)72<4#(H0$@?#4083.;6++,->-'>:4;%8C.+F:G+-;&'09<6D*F*.'H24F+16$G0*0(H=,/3"1+'D%29A3D(6-@C5!'E$2.C)!$&6:C7<H/C<)('9!7#/=*2@
@r9937
AAAACTCCTGCTTTAGCAAGATTTGCCCTNTATTGCTGAAATGTGATTTCTCTTGATTTCAAATAGG
+
509#)%',F<0>*%2"E@)@".6!<6>G=E%7(#:E(24%:61:$A%8;$E='2)3#-,AED6B,8+
@r9938
NGCTNCAGGCTCCTTTTTTNTTATTCGCATTNACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCANTGATTCAGCATCAGAAATAGAAGAATTACAGCGACACAGCAATAAAAATGCTCGGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGNGGCGATCCGATAGNTGAACGAAGAC
+
"($0<C;;@:24@D'"33,5;=+%E5-3*#H*EEC$>7F=2E)5E<D>%?*9+5HD4+7<@:D:G+:/HBD)6*<%4'#/F&EC.1#E$'<!50/A&;02/*<'9<%/*)662-@#3D7"+(#),;."'>&-5?H@C.,1+3/$)2!C<6;G%@/%(DE/@0(8*+&68B/3)8.AA6=@+=090='*)*+GE?2A6*=C=;1,4+?46E;
@r9939
GTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATG
+
>8$AC3&14D47H.B97));8*!FC/(DG@G&$BB>>'*1:8E
@r9940
NATGGCCAGCTCTTCGTCACGCATGTTNTGCATGATGATG
+
$3/(/##(DGG43,/+)<@E,D?!1>#-$F'67.&8886<
@r9941
AGGAAAACAGGAAAGGGGGTTAGTGAATGCTCTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGT
+
**?8*)*5'1$$=9F=(+%5G#*(6#E"3+5*<2B2E),&:)$)EGCH$#D&!'A-E3=(C92C<&62F.3%>::%&.
@r9942
NTGGTCTTGNGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGC
+
!(+&"&+%&(%*%')&(*"""(&)+"++##*"$%)""$")+"$%!&"#%%!(&#!#)('+"
@r9943
NAACGNCATCAGATGCCGGGTTACCTGCAGCCAGCNGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACTGTTGAGGATCCCCATAATGNGGCTGTTTTCTGCTGCANCCGCTGCGGTGATCTGCGCGTTA
+
"%&&+(+##!((+$"($+*$$$"!$##!#*$$")'%'+#!&(''!*("")'#!$&*#'$%'%#*+'$#%"$)&'%"(%%*&*+&"!%&(&$("*+"(%&$"&)#$$#")$"%&+!#"'"')(#)##%)%#!%+$((!)+&!!!%##""*(%)"#&$(#'+)#'%&!'#$')''(*+%)%#*$*!*%"+&&!"$('&("%&!")+(!'$&((%%%+*"(+'&#""$')&&')))&+"#!&+$""&(*&"'&+!*('')
@r9944
NGNAGAGGATGAATGACGTGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACG
+
#$%+#&*!#*(%##&'+"$$%"#(&%'*"*''&"+))!'))!)("+&!!!*#)#'(!'&#%$)"#*%##"#+'"+'%
@r9945
GTACAGTGTCACCCTGCAGGTTGACGGTTTTCCACCGTCGCAC
+
).">)2)#>7.'E>?A"391<(>+*F+6#60:E?E+,"8.7%#
@r9946
AGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGT
+
G2=*6"!,5F@09B5H*"!(,,.,F>8:,)?&95?83:9<$>D*EE7=9)7@;FE%/6//5!8,879,1<CF="@=D@B5307+F-%4
@r9947
ACTNGCCTNCAGNAACCNGAACTNNCNNCGTGACCGNTGA
+
**$!))*"""*$#&'"$'"!%((!!()(+$()!%)%$*#"
@r9948
GCAATATNATNCCGCCATGCGTATGNTGCCTGCNCAGTTCACCGACNTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATC
+
")("&&&!'#&+((()+#&)*%&#$!'+&#+&$*&(&('&()%*&!'&!&!)!#+()"'&"$(%#&%&&!#!"+%+%'&%%+%'$+$#
@r9949
CAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCNTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTATTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTNCTCGTAGGAATNCCTTATTTTTTTCNACNGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATCAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAANATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTNGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATNGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGGAC
+
;4!0#%F5;82H8B+4$,@8?/'@):$;3&HH9=0*&&1<:H24A/6#?%!*8$$392G!-B?0(BFG2$E(4#"?5#?3B!E-@&>;6$4>+()'9F-E56$D"<58E%H/:4*)4B:5(BDDGG6&HC@7HE7C/!594+')D;;:<$'9/-B%7<%@:D"$8)0)-;5>=#4+8-;?G&<;577@C,D$%D)-%!.F5DC!.56?8-&F0(=6"!9>(G5"*331D=<"?4'-5H#6A/9=G&AD>@1)<,E8;19#!'F?$34<=9;;F6F%2->?9<99(#/$<*1/H,C#H6550E2<<?E/3+%);9"-5@-32G#%2*7"*7?0-&HB>+"D%+4>%;102E4:.&$"B:G@-=D8"4@F(H1@H-B98AH3!.B@G":)8'&(G.;05'B"<EA34:1)B%:*7#>C'D#/(('#9D/''66DG*<;96''+/F-"EHB98E<-$E)>3;D%AH*%>3%"#14%9A@#1*18,.,3,$!++%E=
@r9950
TGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGGAGGGT
+
C=)<?-(&;G'??<-F7=.2-'*H3<#*>H+,.B(A2'-D'39FBA
@r9951
CCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAANTTNGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCNCAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTC
+
GAHG:<GG@),%1,D7$3(.D!)+>/>.2,2E'=*#3C>!*=&FE5+$C#!0.564C?>5G2<B/1A.>/>."&&4!:7@1&8E5&3(E7A:7*:2+??&=#+',7</4,C0GG3*-79GA03-$>..<7%B6C3E<A=7H<>&(9,/1,&!28%2B8=.245?F9H!=(&%<'$+$-)".4*A&
@r9952
GTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGAC
+
='='26:)!.,.19:+5A34%4.9%'G5%#22'2C5:9&%9#5$A%>0-A4=C7<9((C*@317DB!%72#<G:A@!
@r9953
TTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGNAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGANTTGAAGTAATATTTTAAACGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCA
+
5C36#A?12$)/<'"4?DA97+!,G78"%%?H.6C<B2!B@G5?E%$+47&54?E$E0'(B+645HC>;+<:(#,,;+&0(G$=)&;?1*EGC5F%-"3/;D52=9,?4C>"+!;"ECC#&C/69CCB@A>-H>48F/7H+/F:D35BD-:>.'C567-B/<89)>(483&"<+F#D#HB<F!80=8'GA1,34,/.&A/37>45C%$-DB%!'"?7<E6%$B:#1)?55"3!E6=A-2@<E1/8(#,%(@
@r9954
NAAANTGNGACNCNNTGCTTAGTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAA
+
!&&"")%#)""$*'!)"($)$!$'+&"($$"*)$'%&&"#&('(!*+$)*#%&#$'!+((#
@r9955
NCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGATGCCCCGTTAAGTTTAATACNACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAG
+
&'+*!%"('!$$#)#+'"!*%&++#'%#&+!$#)"!!')$(!!")"*!*''+*$##$))*###*#'')!%'!&+%$!$)%!)()$*)+%'*'&)%&###"($*+*+(*''(
@r9956
NGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGATGACGACCAGCGGCAA
+
+)+**!(%+!(+*"(+%'+&%%(+$$#!#"*$#'$#")*&#%&("''"(*+)"%!#$%(!%"#"#$#(%%)#+(+#*)*'()&+$'(++*#+'!(
@r9957
NNNGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCANCAGAGTTATCGAAGCGGAGAACAT
+
'&%(#+')+("'"&)%(!+#*"%('!+"#"**&!"#(+)*)!+!$#*#!##(&'*$!))+$!!()'"$'%%'+%!)!&!
@r9958
NCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTC
+
"+++(!''))&(#!'*+$(+')'%+!((+)#)&++#&)$*&($(%%&(#')%&$%*"!(($)%#%!)!&&+$'*($&+(&('&'!$%#"'))$%&(**
@r9959
ATATCNGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGC
+
G3,51CE(!D)?)6'/$$C4(7)0:1G.B2+)*B9F'30+H5A34&E6FA69?A:?!DF1HE@<7?AE%B&HHAFH,@
@r9960
ACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAA
+
GG3&C?(8.F3H<)$4.;:65A<%C$3*?6"095$E7=0>%9,E@#3H+1-(06GG9953=E&65'70:FH(#C298?1"9G1/G91;:B86<8!DD'51)%03A24
@r9961
GGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCT
+
=E?D<3E!/@6&&C7@9H!%/G@EH+7"5B7!.G;3G-1;
@r9962
CCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAACCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAA
+
!;-#44D?-.4&"#'E*>B%%7<BD:76F8)G6;E;&*D4+9(G::-++G4"(3E;,E.")H>@B$>179?;(&;B,A:B;176?>@#@DA9HE=::/&$)7+/=.GD@*G-G,F%$%<D66+3*&0G?3#E,"-$,.G(AG7D6;%@-9&)4@<86=*;#0)2+$9)==9/*C2,><58)H:&2*HD#C=0.5*6
@r9963
TGCACCAAAGGAAACCATCACCCATCATTTCTTCGTTTCTGGAATTGGGCGGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGC
+
&$)163<F;61+"@:6#!@9;D9==1%C8>1+*0?-/75->5AD:#549)0@%$9H4)H):*80A;:8@4>B(E)3/4H2HG/!;-$9
@r9964
GAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCT
+
F2+<.3FC4;$)D;G&;?%70%:C7292@C=*>:F(1@#!;1-:'>>G'*0E,17'*>>#<:4
@r9965
CGGTATGGTCACCGGNATGGCAGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGNAGGAGGTGATCAGCCGCTGGCG
+
5'3GC(#/&$:(::(;FE%9&/4@>"2,F'!D.!D%/#?EB<-+!H,G+HAH*D7-#%B)7C9*!#6H4#,F0:B3F%*-D)<,H##@-8#HH(*"9<63(9@?);5H8:F:%+B9A=C(2&5@=,&(7G>%%?>HE$2G*@<)#/*B>-:,!
@r9966
TGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGAT
+
33.(;)%!::>"5F,@/E1=1%:D4$;%$(E$92*A/3,1@)?!;25)G
@r9967
AAACANTAATCGACGCAACGATGTGCGCCATTATCGCCTGGNTCATTCGTGACCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATG
+
B50C4?C1272<-0>'(A!DBHD=A'!B*&8@A6B!"5=5#8.;H,#!8>/A@#FGH*#%*.=.;0E6*;9."+G+#CAG<71A2$19.%1C+E!/>(2"5:1,@(+F!%7HG@G:+B?#E.7.4EH*13*B5"&A8E>&/:EHBD$<<)*8F/>!&'6$#&921/9-$$G0D'*7:0F8",$
@r9968
TTGATATTGATTCAGAGGTATCAAACGAATGAGTACTGCACTCGCAACGCTNGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGA
+
*<5(FE8>'==&!%&@*'13!6(=%B$4&'HF(?.H+6A&=87%EFAE&:A@<D("8D-75'?'E3-,0=97;5E=+1B.C%1?'=/8%)=)?
@r9969
TACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCA
+
-A,#.D./C%;4+1G*F(<H%=2D'?(-54(0C5=-@D7DH>A-;",#G--:8-1,<5B-8G:9D==/1(4@!E516B###D)#F*;?C*(,!&!:61<ACCA;A>.ECACCFG/73H-E:*E9#>*'0*@!-"!2>BEDC%H<1'566CA&+!+E,-$+H;')4*H)#*&<-!BH<BF6!5B%$3>A@9C@BH1&/A-.1::G7'C!(=7B(1D03&/F!17C+A(*A'0B!"5)=<2&<A
@r9970
GGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTTCCGCCCTCAGCGTACCGTTTATCGTACAGTTTTAAGCTATCGTCACATTACTGAGCGTCCCGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTNCCGTCCGGTGTCAGGGAAAAGGCCNGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGNCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCC
+
03;1F:5)-'$B1#?&<%%%C/(0/8-A-0+%&3)'4!)#D,.*1;3#;A6@+3",+=BF-*/?0"(E58(::*37,"5)A(?/45E?G9HFH@)!4*,4712B8E8:'.57$$,$.:;<GA3%@;)$8+;/>'E.?+A'&!H##)"@G"?(7+?0D:0<1%0A@;A%"#H/)-47<:&6=H3+%=(&5C#9(?B5)B7G--+;)>$B-)C;20=7E.)+:)2?C1.!:>;EH'(D."'//0&)0?G2>;6';<,91-;42<C:<H@0#+,;,B-B75E";=(?.?A@1GE5B=-E42'B/7>0"/'H6?)?C+77<D,)=8))B)%@'7BF.=E5FH38@9CF76:>+#E14B
@r9971
ATTCGCGTAAGGGTCCCGCTCCCCTTATAAACCCACAGGGTGGTCC
+
?$5,;>5".!,;(#81=CE(9F>*#*7D8!653!?=>'&9>;6=(1
@r9972
CCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGAGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCGTGATTCT
+
&?01?;A(;+B=><!!3B$0%<G2A7A3$A2!$E(CE7".B<1.HC66AGG-'>:;=>BBA'8F5-@3)?.$9F@+H(;H<7%2)H,?>8);=$G0G2&B)E*4@*)%52?GC3*!2@9(#/H
@r9973
CACATGNTTAANATNCNANCATNTCNAAGAAACTCNATGTCATTTTCTTGNAAT
+
%)"*)"")%)'!*'!$"#"(*'$((#$%&&$'&&)++"))$$+&(*)!!)+)'!
@r9974
CAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACA
+
C,4(:"3,'?%$A>-+AG/4?7&$/?>.<@'-=(&E?D#%2:AF3@?'3%7=&13%>+B
@r9975
NCGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGC
+
!33/'6+?;#-5"?<1%>/'*!B,<=5A2'<F.D2<@./7,#5/:0CE;'-C(72,$*"04$6B#""-1@B185<E
@r9976
TTTTTTGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGNAGG
+
(#%'*!*!$+&'$*+!*()#&''('#$!&(*&+$*$%)*&'*
@r9977
ACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTG
+
AC&=A1)':B-G#-;%7F887$+%'*3G.0@FHE,#%:#G1.;BF"BE6D:6?A;)&<G0$8BAEH=&0!099*"CGA((%@5:0,5
@r9978
CTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCNTTCACGGTGATGGTCATACCACTGA
+
/=3!B0E84>3):(?-;+58&@/D=03,#3#?'<F8<.7/8BB9<$H!($:(;)#9!/@8;4!+54"E,838,?#C+0;;2*D($E??<4*>6
@r9979
AGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCA
+
)*9;<'>.AE!?9&F497B)74695=2(4>7AAD#H/:.1?<)>0*CA)*B36/!32
@r9980
TNCNNCGGTATATCGCTGCCGGGCTGGGTGTCTCGTGTGAGCAGCTTTCCCGGAATTACGCCC
+
'#&&'+)&&!+&(**#*'%("'("&*')%!")'($"!#+#&)($)"*"$"!+"*!%!&$+%)$
@r9981
CNGCACTTGNCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGGGCCGCCATTGATGCGAAAAGCCGGG
+
/#@%-;B2*:08H%4A6=HA8A,G0;6F>5</;8E@.'33="1#-+<C2E0/!5*-D7,#21,@B1;BE:;.C58/=9#5(1,@2#E.6('8$?E84!%)'DF7+):D@7"%.87:*
@r9982
CNAATAANCTNATTNTTGTTNTTNAGAATAATNANTGNTNNNGTTCTTGCGGT
+
)!#%$%&!)*#$$)"$$*()'%(&$('$(%*%")"%*%$$"+$('&"()&"'+
@r9983
TGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATT
+
3B&$!1B%F?C1&%)4@"2>GD9'7!D+&62E&&.<>//23!A"/>/A252(?5:-B/HA7&32'-A029FE"4D=@2,*$21?7%3#13'F-&8;F?#B5%-';>"@0H1*91FD1+AA<0+F"A::5"=&;0*/HA?CG0>2!53;A=$==54></:-3<"%2:=7&!CCBF(H%7=;44'7(@'2%49161'*08-<H5C4,@37B!#7B3:A$1*#0@7'F&A:G+3./2&%
@r9984
TCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTAC
+
+'%&!$*&"*%'!)*+*(*)#&"**'+*!*%"+)(&$(#!%&("'&+&$#)$!'$"
@r9985
AAAACAGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATG
+
B!#(/29H!(:!>78AC%G0.(1)>BE3!(2G2/5'1FD2/F>87;:$)+G2##"C$B#)-E%,D
@r9986
GGTACCATGTCCTGAGACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCC
+
&'/+4E/2-+GA?D"?/:;4#C3B"3@4C>"A:18+1H"C4,2,?"6-+@&E05'4#B!:A9A'=>3,!H$+#9+%%?:B8D&>/+G%)%*<7
@r9987
AACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTG
+
*G8FB0"A42%$8;HFC,2->)(&B+#)<B?C9H"38#6*E#..5/(#>./(.F9C*3F/6<8=F33@$4H=G;9/H1*<$3=48=!G:!'(5
@r9988
TGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGNGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCC
+
'=>1=9*>;>7;#E50&36)94553/8!+4>=6F.87.24.'7,/<,G*.493>67H:-C77--,B</1@2-5'"70!(7/6
@r9989
TACCATATCGATAAATGGNTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCGACCTGCAATACGGTGAGCGGTATAT
+
3A04:/:B1(*/=+6'5'BF#C8G$H;:>404C-C07<:G8($E6D!*$;*!E>%A=+0)H-'%4E"5!3-EG>A$4<.69"&H)2GA8@5"H.!H"*ADF:;$%7/?#:3@@"=<;;2#C-<0CC47
@r9990
GATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGA
+
02E*C##E874+,!3&B$?@'#$-;FC/F$B34*'#+'=(?-"221*AH13G-)7@
@r9991
TTTATTTTGACTGATNGGGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCT
+
8?B9DG+/:?F'%9-*5?5CF81G+C$2D?#4<@?:,"F(+(#9/9/?1.+0FHC'C/,<84=.%0HB=7A,'=9#:@=H==FA1
@r9992
CAGAACCGGANCACCAAATGCGTACAGGCGTCATCGNCNCCCAGCAAC
+
1:!/7E4).7$>E,?15F?;'.'*.=')-/:/1/DDD@E#/:@-0!A<
@r9993
CAGAACACCTATTTCTCCGCACTGGATAACATGGTTGCNCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGG
+
2C0.7B/9D.(1;128D&!@3*!()9,)D)>+B@?$73;20B>'$#*$%?>@F>*'+D3A=GGG&37(=&*?HC9$@@1*7?6&7:#&21A1C7
@r9994
NGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAAACGAGA
+
"DA/@5'),45,0&/,,'G7+E,<1,CF)<>B>"48>#'#H>;>+9B'!$HDB!*&?>*B)2/>&;5E$0.2H
@r9995
ACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTATTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTNCGGAACGCTCACGTCNGCTCAGTGGGATGCCGGACATTATCGGACAACTGCTGCGGCACCTCAACTCCGA
+
+()*$*$+('('!"!*")&%'*+$$&")%'$'&+('!)+&+"*)+'#(*)+!%!('%#(($!&#('!()++'"'&)&&+%$)&*$*$%)&)&$$%!+$%$!)!')+)"#$)""'+"&$$($'"(("'+*'%$)&%&##')!!*#'&"+(%)(+()#+)&&&!!&"&"&!!$"""''#&(&)!)$%")")%+&$'%*
@r9996
NNGCNTGCCTGGTTAGACAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAANACCGGAAGCAGAACCGGATCACCAGATNCGTACAGGCGTCATCTCCGCCCAGCAACAGCACAACCCANACTGAGCCG
+
#%''"+&('$'$+)+*&#"'$&&(*!#%*!$$$*%()&#$')()&!#$))"!*(##+#(&+!**)&+#%(+!%**+(()#(!"($*#*##*#$('!*&!$*#*&!%+!''*&"!&!#*"#$(#+&!%)
@r9997
CGCNAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGGTCAATAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGT
+
,3EC6)?7##$%,D99!?$6.G1;'.$11%G&+.GF+B1">AD47&%(E*;:"9%4E5=*/0*")#AF@0=B"!<2?>>?4CH,?9.0+>?+(:'?*#=+7D4#9.67<.$HB
@r9998
CCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGNGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACANTGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGA
+
-0@0G"G/9F!!G?,<6";-?$<23A/*9H!E:)&724(5D6+:5>H$>C;5<BCH.5-G44D@6+H9C/"#4H?%'GD7'E<55BH'*+>2:#"0865/#E-?*!$<H>)&/$*.@>E.!!D;!F#5H9874'@'=$(C;F%"@-$H-"'#.#"AE!F/;-2)F?=@&=2)'F(>%90CC1%>F345""<4B=.$49?'G@?FB?A:*8*91F?-BG$#76&2C!'(
@r9999
GGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACG
+
#<!H!@@6GH;B"/).+*30H;C(6)"&@#6?(C=1#:B"8"%6D9,@/
@r10000
GATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCA
+
<:A:9@+@B")2!5*?3F&9)5H0==6:D*#71G,!3D56H38"(.>&5G",@&HF>."63.(1H;)/..6?69+F/:-&=#=H2!C,H!/>!0