view test-data/samples/sample2/sample2_2.fastq @ 43:62531f7399dc

planemo upload commit 0399c6bd696435a7a99d8d8b4c237e5a78ee5856-dirty
author jpayne
date Wed, 25 Apr 2018 15:54:10 -0400
parents eefdd97a6749
children
line wrap: on
line source
@r1
CTGTTTTTNCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGNTGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCGTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGT
+
.2,(:(?3&H7.:/H=)D#C"C&C9D5B-C*,#(42+ED7;(*6C0!$*CA0/E79?8-48"?2:78B-:B>;A:'#394?#?>!1-DB@F)""3;E>&@=%0)&?!&??8,?GF<&D+??2!9!<C3;<=H(!B@,E5:HB-:>.6%C.@5&*,H<2405(EH+EA#59:/@2FD,-=%)(+;,0?+"*?,F
@r2
ATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGC
+
9G:+?#G#D=C8CB1!035+3,=B2!;.2$=>1>C#;$G2*(H$DH(<!HF+$B,:=(H#0*?*"!E>,'5?93$6-+H(,A0?040G;0;?A*4&;>C3'.!+=')3D:"
@r3
NGCNGGTTTAAACGTTCCGTCCNAGATACCGCTGTATNGCCGCGNCTGCGGGTTATAGTTCGACGGCATCTGCAGAATTCGCCCGCGCAGATGATAATNACG
+
$'!%$+%!$#*")'$+*&&&++*+&%$+#%$$*+'%""%#$*#!!+++*+*&#()$+%+')$'#%!)+$++%*('%"#+&%'(($)'!#+&!(&"$($(%)*
@r4
TCNTTCATTATGCATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGTCCATC
+
$*!8@732?C?6=6A762%7F.(=B7696D"><57>7,B5&C'3/B:722E;'E4&/&@1A+<%;E@>79$$0#H%H"?#-18)&(%6:$!E!(31@4-=$.H-)>65$*7---H2-/$.4<(!")D/B743GB3;4E">!()0'>1-71).:"?9FH&0>.@G,!":C8!>!A8@7B-H@HA=2&=;G%"D),?*?"&75,F+)E,;@D><%B
@r5
GGGATGTGCTCANCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGG
+
0<;8G?G"!0)$DD:;.6<:H7?H'7*,F!%H(B@2."D3@D-51(D7":HC7+3G-)%()"H84>DFD93&/6B0G9F9$.@*E'3>;,1D&?G5/"-82
@r6
GATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGG
+
B1796<8G*8:D3.'A86H<8@(A=#9.#.A1((@:=!$6!);E8*?<C'?C:1;%
@r7
GTTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACT
+
$'%2F@#'A>9E1F5%(>H#,GC9&7>%CB&+B#)"#5H%(?H9G,'CF;!:8<-96*5<6.@D18=D.9>2BG%"&E;.;2#4.+2..;3B;;+E$&8@*-#6#?+)=('5H?+,)55(E%H=/<AA%G+"A.<%5=3F=A;'D@1$2*2'2GDH-D9EE=E77.?(F$
@r8
CCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCT
+
*4>64F-%%7E,7,AF#4*+*D):2?:'1E97H.#6::4.D89#D&=*,/
@r9
ANNAATCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGNCAATCCA
+
(!#&'"*'+&)'&#"'*)#+**+*'&!'"%)*+'%"#%&)*(#&')$
@r10
GTNTCAGGTGCCGTTGTCAGCNGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTT
+
D"6+=FH>(>;?#8+)@@6(="556;>)&3*/29,*&F4/%C!AD/'5H)16@E(
@r11
ATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTACCAGTCACCTCAAAAGGTATAGTTAAATCACTGAATC
+
/3%GF/(*>!DB6;HB?+B00>=@BH>H8?!2*C+A/*#2<33F*H,3&H@A+,;"G<6,'.1!#ED"A<86H66(F:(92'.(-@1A$)!6<=;$<FF/B$%/0@5F6;
@r12
NGAGAGGCGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACNCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATCCATTAATAGNCTATATCGTTG
+
"$&*)"+#&&)!%##**$#!&(%*&*)&(%*!#"(+'%)#$'&()%"&$((#(&*'#(#))*&%(+&)'#+!#(')'!*##$)')%!*(""($##'('&+#&'#!$*"+$)%)*$!('*&+"$("!(#'!#%!%*)%$%*!$('"&%!
@r13
TGTCTTTGCCGCACTTGCGGTGANAGTCACTCCGGCCCGTGC
+
@2-2D*001B'H->32&$."+9-(/&((9%4?9D?7%H!E"6
@r14
GTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTNTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGC
+
>&-'AE7D-)":0.8$!,*.:=*0H91,12<*7=H&@766?>>&9?!&4.C%)H,2A(B,=)0?#(?/5<(1%)+9?3B4$G&!'?=)?->$,5%HF.H@B.3@4+.80?0#
@r15
TNAANNATCCCTTNTNNGANGNTTGANNCTGNGANTTGNTATANATT
+
(!!!#(*#""!'#""!"($"(#$%#(!"'%&%*%!*$(**!#"!!!+
@r16
CAGAAAAAGACCTGGNCGGCTGAAGACCAGCTTCGCGGGAACTGGATG
+
):@&9:*2)G"=:H9=C1C815"00A:0<GB(670(F2,BCH#?-("/
@r17
GGCATGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCT
+
A0%CD!B8<3*)EC;5>5?$12>9+,,?/D5C"@*%+%0"F)F'&<*A947.*87?&7/-/9B(
@r18
ACNCNAANNTGANTANNNNAAGCGATACGANTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCT
+
"*&)!''&")&'!!)""!""!#!+)$+'*'!)%*''%'#&"+")"+)!&!%'*!#**')"$)!*)'&%%*'$(&%)#&+'%('&*''%')'#(!$#'("""$%(')"*)
@r19
TCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGNGTTCAACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGATGTGTCATGCCGGTCTGCACT
+
<19>"'/,'+-/A'2?@;#-D'.4?FA-B+<H-!0=:8'-E76B9-7$.!1'*9F##G/71*>C(7BC=11@,E26F/0*99G6.@<6.$9-8B.+4C?&8@4=C2@)@DB)81+<"B,%F2=D*14+9E$@%E*H=92H:2,)**-48AABB:6/*2='C5((FF.B06"%*D3,31&&-EH1,!,;#!.HC#*431GH<G.2=)""G,+F>)='+;BB$%#6A)6<03A70C&9
@r20
GTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGNTCTNGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATC
+
+(*+*!(!)$#)+"$*")%'#"&#*(#%()!)!%&""+%#!+'%$%)%+$""!'&%)+#"'")!)%&&##(#+$(#"&##'(&"&&''#!'*&)&$)+*(!)#&(!%#
@r21
TGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCTAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAA
+
-,!*8?D=D*4;#A:(#.$@0EDE4;<8;D@%C0>A.-2C:=:9&@9'*H2.>+)CD5F7E>57GHAH!()!4%&(B$$$G/(+F>"CACD-$(88'D@5/$<2;49"G!@)F>7=H>+&!@-<)-#;))EH0FBD68DEG1;#&8!+*A$H?'0#C15
@r22
GTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCAT
+
3A@!!&6+F!#;H9<EBDG807<"DDE(8B)?;'&?5F2BH"AC)879>
@r23
AACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATNGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAA
+
F)))E&#'>"74/>@;,'3"78++&G3<>%F:0+3?/<6*0/=!%*BC*99;/%,AF5?<@"%E4/DDF9*,0/?$*!<4>*'@@/>
@r24
GCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCC
+
9C6-?,(=8B2"2$G-1:42><!;3);$F#H4'0?6?&;5D$D>+3*B(=?<.5E$9-#5!!!
@r25
NCAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGG
+
%-@&:##7EC5'./4<<F9534:<+@6;:F-9&31=9$561+DD1A(-&$.#.F"H=0A
@r26
CNGNTACAAAGAACAGAACCCGCATAACAACAACCCGCAACATCCGCTTTCNTAACCAAATGATTGAACAAATTAACATNGCTCTTGAGCAAAAAGGGTCCGGNAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCA
+
%$"!!*'#+#""'$+!+)!)&)#)%*')'("*''')(&!++&*#!)#)%&!&#+(''+('%)*'+)!))&#%'&+)'*)+#(!"%)###'&'$'#($!%)'##%*$#(*#%')')"&'"%*'%(+#(+$)&"'&*"&+)'+%&'%#$)(#%"*&(#!!**#''*('()*$&(%$$)')*"$%%*%+%*(&'$)*&(!$&$&%&'&&#&!)$$'#'+)#'*)'#"+++(')'")$#%'$!#$"(&$)++%(#+"#%)$+(("))!*%*!)*%*(#
@r27
TTTGTTCAATCNTTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGT
+
8!5*5>D!8)0'CG9-%)".DDG>0'-#@'569!H:14=G+$&C<(#A4<57?",+CF-GD7%G-0/G;#B?62>3<;0&-=0:$+E=%",9AB$3-/0+(-2'4/>=A>F($)8$+"$62<'3"DE4H",B(1
@r28
ACANTCTTTCNGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCT
+
"$'!$$&)))#+$(+("+$!+(%()()%!!()&'%"**+(!#!**#$*"'%$&&#&()!&"")"'((%"%
@r29
ATCAGNCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTG
+
#H07!,5!B$-?-"4AE-&E0-%$(?9>.8,9;.50!<4#E@(=#>A
@r30
TTGCTGGNTACTCNNNCGNANTTTTACTTGAACGAATCACCCGTAAATTACGNGACGGATGGAAACNCCTTATCGACATACTTAATCAGCCAGGAGTNCCAGAGAATGGATAAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCANGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTT
+
'&(&($)%&!)##&'!((&&%!*&($+%*%((('!"&&#'("(*+$+%)#*()(%*$'#)+'#!&*#'!#!"!)&'++)$%&*("&'%()#&'%"*#$')**)$*!%%&!)%)'*&)("#+()*+"&&*&&&)%)%)!&&*(*$!!)))&(*$!%"!$(&)&#+)!"'*')%%$&)'##)#(#+%($%+#")*%'!")%&!'##""%!'&(!#("#%$!(!&('$*$'&'%$!#)&&&*!)+"#(+!"*!'*)""%%%"$%)#"&)''+#""(*)#'$$')*""&(!%%&+**$'&++
@r31
NACNCANTNCCCCCANTNGCNANNANNNNTNNNTNACNCNNNNNCCATAAAAATNNAGN
+
"$#!"#"!!#"#"$!$#!"!"!"$!!!##!!"#$"$""#"!!""$"#"$!"#$#"##$#
@r32
AGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAA
+
>#/<=6!$H9.+5:C=HA#;G0>"03@G$;67(,A)0(H4D%;-;H4@9F3!<),*/<"6F
@r33
AAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAA
+
8"=9B=.'<2'=F/2EG;A(/33E*;0HF9$7:%C*"3C&>//,B*,8,A+=E060<H@97046?#;!"%,$$8(&9
@r34
GGGTNNTTGTTGGCNACNNNACNTNCATGTNTTCNCNTNNCGNGNNGNCCGAANTNGNNGNNGGNNNNATATNNTGNCACAANGGNANNNNNCCGA
+
"#!"##$$$###"#$"##"#!$!"!"$#!$!$$##!$"!""#$""$!!#!###""!"#!"$!####$$$##""!##$##$#"!"$$!!#"#$!#$#
@r35
CGTAACGGAATTNTCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTG
+
F!-8>F?-+E4D4#515<+*6<3(),*7*@?EA':+"%-B03'A>=,(C=;'+*A!
@r36
TTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTT
+
.AEG;-:A75!'!19?E::=9&5)/4(B'88=83A<?::15!A+5-H16:A5@D.-%D::)6>.G2!H2A>%*.
@r37
GATACCTTGATTCTGGGTACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCG
+
1?)5E8;943G#4=:?$;5+=EBH<8$*6.F*&D8BCC.1+;28'B2+1GA;@"-G7).G*;E'+F(%9@6%!3(F-D3$.,0
@r38
GGGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGACCCTCAACTGTGAGGAGGCTCACGG
+
C$;=.64AH/?7:$<<%E+;:1<A)FC(7#@)41@1-)"H"/505=,3!660<HCD<%;4<6;0+<,'(<609F,/@0-E?')88;"%>7@,
@r39
TCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATNGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTT
+
5.DB33E2A;G7;*/E>)H71E?1%%-37@FE"1#/(2!#F;E,#4C$>6'C9F<(5,D,&50)8A,0F<BF7H3.E)7A@6=$,&,#<H(&+"C+8/G<F:6#:=3-:="$>%H>;*'F47>8"29207H$E;*.<
@r40
NTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGAT
+
,#>1>?'3$$*C7>%)8EBE9&3G5,-"-6D8-,;D=F74<"G0!D998FB"E
@r41
TGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGG
+
7H0E/D*4#2@-=56#G84.5#"G>GF!GF:>6!2(/6;%6GD<.7!#"?"H1,
@r42
GGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTNACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCACATACC
+
@/'5:C163!G))@H537HHB.73G%'1&&D*8A-?"D%>H.02,@3AE<C,4-H;>3&9!1+3>*H<*0:53*!"98+==BE",=(D-8B:23$DE>@#$*?A+/#E>4"(<B>,(&'.%7-=B$-F,+-9C<((./)@7?18E;;15B)F@$!H)(24'.?H8$C%(5:,0"!B'48A+<H>%DDF9=,CF37#!+).=28=1"44?0D(?/@G-+$8.H;E6%/4/5-<)%"B+8<B
@r43
TGCTGCGAAATTCCATTNTGCAACCGGAGGATTTACGGGAACC
+
'<?!G45G<)(!2!4B3!D8GA=D1F:%(%H!116@2"%/*D<
@r44
GCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACNCCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCNGCAGACCAGCCACCACGGCAAATCACTCTGCACCTNCAGCCGCCGGTCGGCCTCACTCAGCCAGGCCAGACCACCGGGGTG
+
%(%+*%!"$)$&+!"'&!)*+"##+()')#"'###!'#"&!+$'!"(!**"%"*!)&&$!#%!+'"$#+)(&%%$+**+*&"$)(%&#%+'!&#(+%*!(%%(&)+$+$('$!$*&"&&(#!$##"!(""'$&"(($"%+'))!)"&&!&%$')#*)&%%+")(%&&*$!*"&()(%&'*)#!#+'*+(#*&!+()&*'*(*))'%%!#(!&(*&"+!)&)#$#
@r45
CCCCTACGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGG
+
3&;E&=62<$!'!$C@##72/("7&1;?9=,?$*"B>:!?&)48B5E*>):-:E!HGA#4%-H>.%&=:C.F-3!)F1<E%&5;>C78$:#E"#=D3<(EAA9$$-D/37?@*+D&5/HH*>&4'D1,$6B&?25:=E.8?9C9G/%A3F#)3>?F!'-;$"&<!=;..4/,!7,::CA>=&$:&,.5D23)D(>A5/(6D=F3!DBG#C9F$7$&B59;38H$2;5":H$F"(<<9C-!EAD0E>
@r46
CNGTATCGTCTNATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGG
+
*&(!+$'&)"$*&*!$%)$#)+&+")!#(()$"((%!"+$&%"%%)+'$"&%*&'$*#*""#(++)"+(""$#&$$!!'($*)'%+'*$*#)!"++*#%#%!)$%)$$*#$%+)(!')*"$)*%%&"%((&(&+%$(((*$(&(+&%)%*%"$$%#%
@r47
AGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGANTGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAAATANGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAAGTCCTTACGT
+
?)<>&%C614!E:(B4>G&DG/%E9H'*6::"&90>D+'".3-"D*?(+&'EC80"5",2C%*-4C($3D"!G(*:06#-E)B!G08;;3C511'5*63%H89*2"!:G&?#%B3'&%9GD/"(4*5D!H.%*(=",*)<2;A/H
@r48
GTNTACNGTTAAAAAAATCTTTCGGCCTGCATGAATGGCC
+
%'#&#$(+'*))+*+&'"!#("'&#*"))&#*%!##(++%
@r49
TAACAATTGATTGAATGTATGCANATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTT
+
54%B>1>H()34GE+D=:"#178D,3,'1!@200E*DG?0/?013..6<+B./$.=+.5!5.0>4;3"D4/1>%/:#"@:;ABH.;".1<8*84%&;"CD20&
@r50
GCCTGTTTAGCCAGNGCTCTTTCCGTTGTGCTGAGTTAAGGGAATAC
+
)5#,&B@9DG?,E:A?!*<&#?->F%+;(1=9><1A-%A/80&E4->
@r51
TGCCCGGGTGATGGCAGAAATGGACGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATNTCGTTCAGTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAGAGTTGCCAGTAACTGGCTG
+
(D*D/D;,;'54?G.;GC6*75D&F1:45?C+&4HG>1AC<>&&6'D?79A-'C0$G.3/H=/(%H.;B5/7'3H1@B*9/-=40>(%-.2..18;94)2H+;.+<%*$4.'-9,2'7D5&=F$29D'.<:>E$64BAA1%011H".#+;;'@8@3<E1B--1F>(@H?7;'$+!D,D'6:@<
@r52
AAGGGCGTTTTCCTGCTGAGGTGTCATTGNACAAGTCCCATCTCGGCAAGCATAAGCACACA
+
6"8=$3DHG)CH?8D0%7/B)423AB1$9@>-C@'#)-:2F5CH$#%*9+H;$@+F/ED#1-
@r53
NGAATAANCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCNCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGANCCGCGAACGAATCAGCAACTCACAAAACGGTATCGTGAAAGAAATCAAAGGCGCNGACACGTTNATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAA
+
&&$!%#)!%*)$+)$#!)*+')+'(+%'(*'$+&$!"**&"""()*!#%)$#%+&*+)%!'"+%*#%%$%#"&)*+")%(%"'(+($!)*!%++%!!+"")'&($#(&%$!*+(!)#+'()*(++('!+"")!))""&*)#)+!*(")!"'+*%&+$#$#)$$#'&&$(("(&!&$$*"(*(!$!%+#)!%%&$($('($+(++"*%+*&!'"!$)%$!*)$')&"+!'&#(&%%$+$!!))""+!"&($##(!)(%&&+%!*($"*&&&)'*!$%)%(**&)+!()+'""##"+!#)&"(&#*(*$%#
@r54
GGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCNGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCANTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTG
+
<633C!6&"5/1-DF==<E-3F?<D(38F46A*H::+3E5GF6E1A+<68/9!>-HF2+H0@'8F/##-(6B7;86/0"E*,8A8%F7(F9D-()$)3'F$ED,2=7'B,-:=%5$0$DG*H%%>8#)*1>B$89.#)?><&0@7:'487)<5*5**29%!1H!;D8H;.;/9(H*/&1!7-<>.0/:<F)C>..@-;>(<H!)(3>36C&#.1!-<$=>0G?C16D=2G>;&H?>)(10,@
@r55
ANNANNGNTGGCTAACCAGNCNCGCCGACTCTTCACGATT
+
$"%("!"(+$*)()&!)!#&*!%+)'%$"(+!))"#+!'+
@r56
TCNGATGNGCNGGTCTTNGTCCNTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGTAAAGGCCACTGANGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGNGGCCACGAAAGCGCCAGAGGCCG
+
)'")#*""!#!)($"$"$'"#$!+*%#!+%"*"*)(#$!&*!%"%(%$$+'+*$+*(''!&&$'(##&'!!&%"+(%!*"&#''$+(*!"('#*)!!)"+''$!(+'#*!'#)'#&*(!$#("%'($%(")##*(&"*+$""##')('***+)#(+%+$&%(!+""!!!"*%"!%+*%("%$+&&!+"!!$'!*&&(!(++#+*)"%&#&*()#$"%#&#%)$(%&%(+*!)("")&&+**#(!'!%"!%+*'*'$'#**'"$'"+!$!)!%++))*!'#")&)##($++
@r57
CACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCA
+
6@4/8C2;1!&,F::&C()>>C;8B-#0>!((+$!@;F'?57143#9G9A49&/2+#98H(-.4'!0@?3676A+<G1!+,)=#*E/G0%21D2C
@r58
CGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGANAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTT
+
+)'*#'+!&&$''%%*!+(!+*$**()(&%+"#("#)"+!!!(&#!'!%"'!+&"&!%+%#*%+**%+%%(''$%"$'&!*$!'+*!***%!)%+*"%!)
@r59
TTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACT
+
2&35!)%0AGB?;;GH&$'E9*"#'6(*8G873#B0,"E&8/G
@r60
CGAATATGCNGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCA
+
E)8D8?;*,F,?50&8(#A!)5+94-#%5D-(4<<*DG.D/$<#6
@r61
ATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTGATAGTTTATC
+
'.;6@/2D2-2.28>=F0*B9CD5@$5:<0,87)*5+>1:5">2G-A7G8.E0,,6#F?-"#?<81.%*>8A-(:DA!=/:1C)D:=21E)"F"4FB26
@r62
AGCAGTTCGGCAGCCAGCAGGTGANCCGTAATTATCATCTGCGCGGGCATATTCTGCAGGTGCCGTCGAANTATAACCCGCAGANGCGGCAATACAGCGGTA
+
H9D<HD95CB31!#')A66&F!?&7<':&CD@(1:7CA0.0H,5-?;(%2=;(!!@B2&6,$"92AF</:!%8>#E5*/H!)HA(0#1E<?)3(>3=$5%A4
@r63
CAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAACAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTNACCGATATGCACGGGCAAAACGGCA
+
#G%F%72)5+>8>E(B+G506?B7/?0&02#%8>07G>;B9AE"9G98!!CDDF&".D?@D+8E#'<5F<B#H>:&A<,3;+@<.2!"D+;5E.*-=GH>>(%,28*%7C4"(,12"><#3:5)7C6F>92E(%@%,)#5>)7:)1%=DD'6<$%</;F(7'=8<E&"84+
@r64
CATTTATGGAGCGTGAGGAATGGGTACAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAANGACAACCTGAAGTCCACGCAGTTG
+
&11>33.G1#+/)91'/9#;8;*(!)E+H72*9F'4%,+$1AH"+#04077-"0C1*3F,(%,&*>$=;D#1:*5-=+=>%008AC>3
@r65
CGTTTAAACAAAATATTGAGCGGATACGCCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTNAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCA
+
+EF)?=;=5380)*D7'>-.B?:A(":,58.$B56;,=2'C,;(2,2.B7'E0//,%<07E#D0<GGE8;D2/!>6;(H(!516$;E-+=*)%0A68:-C(4+4/"4'.<0/$C1#D93,=><.1DB02BA0?/%2$F&5C-E$
@r66
CTATGAGTTGTATGAAGCGGTNAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGNACCCTGTTTGTTCTCATGTTCCGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAANGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTNCATGNCCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTC
+
!%*#*"("++"((&%$*"+$"(%(#(!$"##)*""*)"#($#"##&++(+%"*%+))++$((!%#"+(()%%"(#&")*+&##'$%"*)'*!$'&%%)')%%(+'**)+%#'#'(")(+&$'('%*$%"("!(#+)"$'&#*')#"+%%#'++!$%''+##&'&(&'#(&')#('%+$++**%!%!#)*#!"&#%)**&"("+++'+*"#%$$#)#)#!(')""'+"(!&)'&&*"&&*"(#+(!'"'
@r67
GCACCCGTGCGGAGCAGTCGGCCAGAGTGGTGCTCTGGGAAATCG
+
,1D@'%6@'>"DED8:#EF*)!3!DG,9A"/$F<-EF=+E/+A!'
@r68
CATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGC
+
(9>9"#>B-&#20-+(19B;FCA="->"?D)&*H:HH8BH/+D9-?G+&"E&?E?;6<$7=A$9>9C;?(8D'=$)02"6"54@8@/8A+&&$=13:0#715,$#(93#9+(6!DH.&F,?18<2=3BGF9$?;@.362+,@*):DC=
@r69
GCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTG
+
@(:E?=A7@A44&06/:1'CF90<!@1A'B+2&&1/<:,':*?!=:?77,@(E?10+3G:9#1%:B/>:AD7=
@r70
TGTNCACCCTGCATTCGCTAANCAGTGGTGGTGCGNTCCAGAGTGTGGAACAACGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCANAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTA
+
##+%)(('+&("!%$"+()(#%&$&$("))$$+($%(%+#(!#(%('!&+(+&$"*%##)'")$+#))*)$*&)%!(+$#$+)+*&$%$!'&'$+%))"(*!'""+$"**&%%"'%*!'&!#)('&*++!*%%''(')'+")#%)'*+*"$&"!$!)(##%!#)")!%!!$+
@r71
GCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTANCCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCNCNGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGAT
+
>$(3*=?<"$""%113&@-<,.6-B-;"?"G+:#,),9B'9A>$E0%>0)!E?"8!'!E5,02A@&?-7;H=E+HH748%?(16?GFAFA?F25$*<1H#*G/%D01H3&?F"8'%9/7>9)<,44B8:!3D2$"@#BE(G%:E.C)'!B5=066=/'>'#6CC"93)B"%:!5($'0G&$F=43A0(C/!CF75E7/04**1>0-A<#(32>@/H/*2BA!E$)>"*@02?2-)91#:1(40=!"5:D*'*78;C*;/'$D$8H2A.D24*.'-'/0"*-$3#080,G0F.>=3%(6+/;85F!,B!$7F5G,*H5/D.7B)0A@95@B)A79:H"8C'E&H/#);A>C3E7<3@#0,"7A7>9>2'HD<?.09G%@
@r72
ATTTCCAGAAACGAAGAAATGATGTCNGGGTGATGGTTTCCTTTNGTGCTACTGCTGCCGGTTTGTTTNGAACAGTAAACGTCTGTTGAGCACATCCTGTA
+
)!0)72%/$.#;&(6F11'1<;*:!+/:2/G'?%"*!72G99;&C9!39H5F=/&/>.A<F=/8$C<+(>3=;>$/&'13'0:(0$:<1>5/7?>713.5%
@r73
ATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATG
+
F2D=>!<%=&+H/1@#3!"7&*?C"*:->%!/7D-%?(?(
@r74
CCGTACCAAAATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGNA
+
@2>.$%42A84*HD0/&>C@F$C-)!%EA*#&49DH.,69?1&@E&-
@r75
CTTNNACGNNNGTGNNGTATNNANGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCNCAGTTTGGGTTGTGCTGTTGTTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGCTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAA
+
)))!#(()#&"&&'%(##!'"#+""'$**#$'$*%$%"#'*(%&!#%*+%*&("'&(!$!$*)#&)#"%*++&&'(*)&!#'$")"#!!&)$&'*'*!$)'%'+)')&+!###)$("%)&"#!"%)))*#'+"$*)#&*%"%&'+#+)#(+("*)##&+&%'%'$#**+**!!)
@r76
ATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGACATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCC
+
D<?"95;+F<G56,AEA7('?&;>E:*E!$GD#02B-(D*87HC:<B@AE.0B=5%>A1.*;:(,>4'F:@!#'8&'ED="*A..E=!'!)(F3CD5&/%08%@(!8=GF.2?.7G<<>>!!30G+H)"73<E#=4D*
@r77
TCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCANTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGAGCTGACCATCCGGAACTGTGTCCNGAAAAGCCGCGA
+
.!C$@B/0B&.&6G<HG'A./7G3E7*8B<)8;+22<9+2D7F/0,0729#&7!58196'(?$+3"5>2(%'@%H4A;48">(61:++*$8?(&=@##HC+7<&G%$1-0,E295@+0CC5.4!*,3G7'%@'H&1C,":'.B
@r78
GTNATATTCCTGCAGTNGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACNAGTCCTTTGTTACAATGT
+
*(:6<';3>#6C;9E/'"8-D:/E2EB0"DC7D;G-:()-<-D95D.AC+EB$5/0>$&=$38A@?=E,!;?6*'(9!
@r79
GAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACC
+
<96&-(=4(62;FDB$=CG?HA4,5.025?6>,",(>22D-4?/A(>F?HG(-3,/5,-CBG/42F*"#"/(,A-
@r80
GGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCNGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGCCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGGTCATACCG
+
C=/C&:B9?*>"+!841HD*$,?GB&5HFC86F.$)5!4A5"!(!)6BF2G0#;B"73..%')4F%,CA-'5A*%(%-28G4>*8G->@$B#1/:))A<1H*04G<:'0*+18-3&$.8879D940-%/3-75'44$>7H'A3B"(19%18=+H"E(68<1/'?20;H@,&:)E"$!+07%";&H3HH%H0=AF<!3;%):D
@r81
CACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACC
+
=5@.,/BH8@-.!B;#A<>B360;2)-#&07:;$4#8?CC80FH<E1+F+/1D
@r82
GNTCACCGANNNANGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCC
+
&"*)())"'*!&)+%#*""*%%+$$!&'"(+%&'%&)+$'&(&%&)%)#%%'%&##+'#&$!#$(+$+()&
@r83
ACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGGGGCCATAAAGTC
+
D.<$<GH4C'%44@"0/,6%C,)FDH!+>'*)%'F4C,#0F9,F;05'"*H&=D0*#6@<5H%<&)+,>
@r84
CAGNATATGGCGGCGATGCTGTCCGGCAGTGAGCAGAACTGGCGCAGCTTCACACG
+
5:G((*1+D5A?/<90.?8/<?*1H"@1A@CD=?);G89)E@D4>%,97'C@/A4F
@r85
ACAGCCTCGCAGATGACGAATCATTGGGATTCCCANCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGATCACATCCGATCTGC
+
?.C<'+'0F%7@HHF;7<#%ED*#>8;:.E'?*6@>=:32+DEE%C4C9>"37%*!+/)-4(3->H1!(?%/,-,&?<-8D:4>('/'1)-F<6A)!H1@#'(=E=/7
@r86
TNACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAG
+
'!3@GB)B<=4."7B/8>A0B+CDA%:'3.#=81:(:.E"%'$3%3FD4-/?%
@r87
NGCAACCTGTGACGCCGACTGTGATATCGCGGANGAAGGAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGACGTNTTGCTGAGACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTGTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCGGTCCAA
+
+@7.?*>$6+>2$=G3>9.7=CG5*62H@:&4"7>B4>:$=,>=D.68!-$(=?E<.:2B@@B!C#F?147H4A86A$&F4$9)'9>7.@$,439'/!BD11"$:7696)31&:<EG,'!7C*@>-41#C%G;:,>*;"/E;-5"C@,"27B7->--@>.!0#2F3+7$="">E5+BG):<'B*<@(
@r88
TTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATNCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAG
+
@1C6A:0,%D8;E;.*F!'6;+.CC1D/09716+61D4>6G$#2<%*"!'#$@F>)%4BFBE&"G0;#@5C?22?/%GH$+84B57A*'(&9#-C2(80F,$D6=,>#<"?>$,54$BE<7C:
@r89
ATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAANAAA
+
'->30:%"2-)&).-E651.?'94>D><)1AD9<D%-+)4A)<*)92E=2)+&*&05?7H:8B+&2/=5+-H'=>4$%,7G?89FF.?(=
@r90
GCGTGCCTGAGTGTTNCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACA
+
B3:B0$,+.$38&-!:5D?"=39,,E+0/C<042)?2)1<>7600'EB-2C=&+9C5+/6.6A9+B(!CE?G??@@'#!%E)E)E2:+7C;FA1@.8<H%;@6$9A*,#574!;$C.'@=6:D!9="/6*06F46+,@F%'*&B!>*7.>6255%C)F!=@.!&E(>70:.H4>7CE)H&HC$A:C85H*#6#53976*9)F&H<2,%!;+";+???DA3=3>;?/','59<70-$"@."%5'34@DD""0)A0*A(A8)#:
@r91
ACNCTGGNGGGGNTACCCGGAGAGCAGGGGCAGCAGGCGC
+
&&"((&'"#!$()*&+'&%)*#)(**&++$*&)&"!#'%"
@r92
NTCCTGACGATCGCCCGCAGACACCTNCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCC
+
"58"-9!;D>B46BF<#;@@%,>D*<E+@2B;6&=3"">412<(#.%%1>?B,C&H)9E1?+3.<@*2BF
@r93
CAGTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGAATGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACAT
+
18F9$E+BC8ABF1$E%/9+'@%>FE("'*28;02&:<+@8(;/CDB7+);53F)$<!E:H?*9!?>1+!2>F%0)(5!0;>#*G))1>?!8@B8F,,+F5C>=0524+-51&6:&,1"09AFH8E8F#7
@r94
TCCACAAGCCCGCATCATCGTCNCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATGCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACNTCGAT
+
<661**@A!(7B.370CB$&AD5"A,#5"B$00'+,C8@>G/H133,94:*0=<3!3F$*<&=;B.0"?2:%55);&&+5/,"AC<C67D7D6>6G?38(6+"&EAF-D397;6'-*7)H#E%7,)8+"B;"D!46+3/EE.&-,%D1?)'/+?H+B)/'@7E>D(
@r95
TCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCGGTTGTTCGAGGGTCAATCCAGTTCACCT
+
4+35*71"&*##1%8%)!G=0-";.+-B1')G%#.)+D9G+B"8#5#H+"3FBE3&>'H'$A>+-'5E"284?65F>/5"$$&*1/,"?+3$>3$<,>
@r96
GACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCCGTTACCCTTC
+
.7(5<<B!?C+E=CA.8H,%A=@75/G8A",&8;6/A#:5/$5"5F!&':F6F.:/%G&
@r97
ACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGNTCTGGACAGGACCAACATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACA
+
A,@*7?)B0$+8?&H;12GC*918@B2(,*5B=?/>+$"D3H2>E:@.B%6"3??A8'6B31%/2%6"59;#&D/.997B(C.H'37G*#FD%*#A/8$::93,1<27D"E./-?+2#.E!76BH+E.('4/1!=44F<,GDH>E.11C%@=2&'5&%346%"B<8*BGF"!@#*846-8A"1D=F<:1%DH@1BB.
@r98
ACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGAGGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACNTTGCCGG
+
3(/++5"22''=E%+>@H?"<$%B3/+H*/C?G="!=2!#5(=97.<"0*D17659G8*291549FG:(2.?78<*5)65-G$#:@36#+!#??F#1-3;/!#H3=8=.%3$$H7H3=75;%*>%9#9$A;'.CD4';.$#,-A13"*C'BGAC3,:=DA->E-%3.HFFH%+=@#2,#+-!0F7>+D
@r99
GTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTANTTGAAGGTTTTTACGTCAGATTNTTTTGGGATTGGCTTGGGTTTNTTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATG
+
,?6HC!460)%9*8/7"G8:H28,"<%56<*G"2%E"H8$-H)<8,6,86:6:.#;=-6B$?#1!,B/!;!12.D(A33>E8-F:6;0@@4-CD($%'7!CG;A'440'/H5+;D-D7-/("H$H6%974C
@r100
TAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAANTGAGTAATGAAATTATTTCTAACATTTATCTGC
+
)E;35@1,7F--C+3?F@<".'14=B'CF&><96=<7E"*,C>!;'FCE0D-D5&E/H2:B>(?H?G@#G%!A:7,
@r101
TCGTATGGCCATCGTTGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGNGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGG
+
<*=0BE14*/+=!A#76?BH@;F@%80AH.$'D-<A023HE&#D>$-8%#8D&/.E8$=%9"G?A;3?4CE->G$H>0:+3:(8:'?FE#9F!+/#(9B/AB2/E='03%&#H/1,@2/FBG.8"#CDD37E5F&6+':AF>@?3<C,*F8#4)70G57B"8@27@%#<1+H'H6D50?#,+F?9!'&,+&*'*:BBAB(H5
@r102
TACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTNCTTGTGAATATTGCGTTCACTAAATCGGAGTTGAGGTNCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTNCGCACGAGATACATTGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCNTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGNTTCTGCTCCTCTCGTCG
+
5!+>73+!A?/,=96>@;?'+GD-.277;'C"6-8B)3>3!A=BG*3-C(GCHG.0!-AD<#,+A8%+2"6A:024?0#=#?:#$8!%5F29*3A,#+867B<)<$.'1+/F0"37>/3D82#B%D&9:96"C)3.->5@$42/-#3AH+1?(/G)CH-&3DA!F4D/:,*=F#87GG3%E@:"6(-="E72D!45<@/53HD=F*8-,(+-@&,A#&<.:*5D&&G:FB7/(#B<308A3(,?G/7*CD9B'42$E@;8?60=2/+-@<#2+.E8$8#GH/</
@r103
AGGATACGACAGAGNCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATNACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAG
+
)A680:5H7@$FFF3;1-C$;=AG;H)2GGE.7$(F#29%AF)H.)%%512&)E:$4E(!>/F<.&C0A2&&=$.CEB-"D()"7B""1*8!:*0H!F7#+,)0*#G0<2"+GED><(58GB"5H#)+,%(;&6+>8"B)'H3'B2:($,,#
@r104
NTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCNACC
+
"<A.'42(,>1AAA92$#F65D/:13(>70+A:5%=!1,1CA$=F,0G5"1B/'7&+D*<1G-0AF;B")5B;@/%!E$.>>01,GE@..)"/7%0G;*)&-!:;5(.=7<#;22#
@r105
ACGCACNGTNGCNGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTNGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTC
+
'%(")!)*("'(#+#""*")'')!#!+$')($&&(+)+#)+'&%)&"(!()&&()!!*%%)"%$"%%%$+%(&")"&)*"*+('$+"$('$!#+&!%&#**%!)&%)&")'$#(!*&"$$(*%'+)$+)&)*(('++*!$!&+$%&*+$")&#"
@r106
ACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGAT
+
BG.D,?<9;8&=%8(FFH.H>C5=3.C+9!-125B"-1+;
@r107
GATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGA
+
.2<EG-0!&'/EG+D-36/":F4)%F2+30,AD9C'+5A+?*!%A/0,'.A,<><&+%#00E50$;#
@r108
GACACCGGACANTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACA
+
70$9H)F1DEG:&,B9D)7A-'$#5C#+-1=44C7&:3@-"2D=C86-%--*53
@r109
NNCNGGACAACACGATGTTGCTGGGGAACACACGGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGNTNCGGACGCACNGCGCGAAGGCATTAACGCCT
+
*((!''+%)!"'#$)$'"#$*!(*"*#&$))#"!"&!$!!")$"$")(#'$'""(+)($(#%(#+&''($)!(+'%#'''##%*')$*)!#**)('(((%+)
@r110
GATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAA
+
B?;6/?:.5$D4:85*!&24%?>;?21"?,G!>)@4!.>!,*5!8-4*4:484,5?;)BH:8.-GCH#+!.;<&
@r111
CAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACNCCGTGGATGACATCCCGGCA
+
=$<.BD":9@3793@:,87/8H(3@@85027;3/<B*D442<'4;'A)(+F-'=:<G-(>0/0=/1!'$F,;4
@r112
NGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGGTGCCCTGATACCAGGCAAACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATGCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACG
+
%*1'")D#/3.$!85=)F*()$*+.(?H*9E"3E@5#.C.D.?A".1B"GE?D(0(53CH(+78>C%.8@'/".2-*:(?7"<!2!2%.A*?A"=7>=<A,8?#F5(=G24?"<%!+(D?EH#*FB-1B!D/#<&0-!7*3703F2@?73?>3>>/8(0H*H;>*8@A,C/H/-HBB711B>6D75'<$D=:-!&2A)=H1*(0'@,
@r113
NAGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCG
+
$+&)%+!%)!#(%&!$$%&(&%&*"$**'()*#"+**)*%'&')''$"$(+)&(+$#%+"&"*)&)&)
@r114
GGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGA
+
E?5E&6GG$7-+-/.3=5=5;,="!B-)9/(((3*/GC?DGG+A,>7);51:!H%=:',@C08G)"G)DE<D?
@r115
CTTCAGCGACCTTGTCCACCTCCACGCCGGNTGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGC
+
F.9'A+'="6%D2DE8>7,'8-F7.#E:9$CA*8(;)E34H"!78)H7:9;#1@F,5#$+7.6,&!F**%8?89,>(49B$<DG*%10)5)@39D66?<A@G;>5206B8F6H)%&*.:**-0E3*D6>G2CA68%%D/?=B%
@r116
AGCGGAAGTTANCACTTATGAAAAATGGCTACGAAGTCCGTGGCTATNTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATTGACTATATCG
+
60G"7&>G%4&D"<<*5$<2=G+6>!*%&0=)G6+",;5CE2A("G0H(C)-=!8/:(&.6BC"F?&$=6*'>.<"$C6EAH;=$>,0%/<#9H8!D4'74-!2'A,*35HH(@B))3H+#AH1"C,-!D=D0450(0
@r117
TGCAACNTCTTGAGCGCAAGNATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAG
+
%@B6+#>&=!%C0@6>A@<7>--&($)0+799A*!7<**4;'=/#)@('%2B707F!.54C1!G#5?!DB-C:F;/760D
@r118
TGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCNGCAACTTGGC
+
3>HD(3:%F@=&)$<7#8<259"$*)6G?(*<8E<9'6HF"C4@(6H#'$5@#%(,=&=0;-2/?2.6"@@7H>,=F"EE!=;10A@?+=74*'+(:FB$:E;
@r119
CCCGTTTAATATCCGGATGCGCNGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATC
+
1D#,/&!-:'/:A8&<81>!?<"2=.@@"E-C!"@#G?<5,E&7+&!1E578;==G2'23=A&>B&#-<*#$81,/F.+8'F2F.<)*#,H3:B
@r120
GCCGGTTAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAACTTATCCGCCTGC
+
23>+%;G6%*;G=B-!+)7,G4G/"87HB5,E8$475*0;B#FF(4-#@6*(C97$6',G;?0H==@-E0B/E%4#H0%-7$$
@r121
GGCGACGCGGCTAAAATGGCACGGGCANGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGNGATGAAACGGGTATTGGCGGTATATGG
+
#A/">>A4H"&%1+H9&/&*'@BE-<C)$H()&1F*6,*58E5-;<-A'!061>2E5H*=-B;*?.6/;'=@$5;.C+-@E6CEG'HB)"%11,--<%CG.BBF8>9&4:*'"140!<B,H.<G+#+',?!/7HAG,)9<3-7F,<(<E$!E1-')&#(D)E6AA;$,42'>=C0>
@r122
NTGGGTGGATGGCAGGAAAATAATACTGTGGGACAGCAAAA
+
#<+<,+:<.;FD4+2B(*420+G'9,7FG*2B*,4.).6.?
@r123
GTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGNCCTGCCTAGGGATTGGTTTGCANGTTACTACCGGATTTTG
+
D=%%8FB41(A)(47F39:;6:E&4=C97'3H&2B<#;F(*-'9%*1C31!=/D&8%6G7'6!.522H5)2168E83.(2D=/#D3.3)+#F/%"G
@r124
CCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCA
+
(?/G!>?4$0@333!BH'%9@E"#&8ADE',1.4;">%B!#=G*074'77(
@r125
TAAATGCATNCACCATAGGTGNGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGTGCTNTAC
+
+&&%"!&()&")!*%'((*+#+''**)*"!$+!!)"!#""*+"(+!"+%!+!(+$+*&(%'%&*%)(+*%'"))!&)*()&&'$$#&)$*$%'!+!#"*#+#$$*)"
@r126
GCCGACTATTCGTGATATTCCGTCGCGGCTGGCGCTGGCCNCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGNGCGTGGCTTCTGGTGCCTGGGCGGT
+
1:&D07*3.%*%"7<3B8.,$H<$+$;C>'2/B?C23,7#D3&6A,1B8*F'9C1@9E4%6=+*>?"+(5/C1E%#@'>!)30>))!7=63C;7!H5##(>';E:7B89$!:2;(E1=--D.C)
@r127
CAGATAACTGGCCTGAATATGTTAATGANAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGNGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGA
+
<+)!..91-$:+#4)2F!E<<8F1#-$53<>->18.37#>%1">7@*?"##F=H>AG)'*H8B>H:F'>4B1!@;A!,F06=(9&@$6=D9A/1),D&$>4)=0"*E&6>/=/5,B$?"9-14)"#=D%4*)$//B3.8(+6!F0G18E,?)'.!B&2"94HGD/CD%/4!*-B$C=C@3+@H75GF"!:"(A>/'ACGF%G@A<7G*
@r128
CTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGTGGCGCTGAGAGATGGCCT
+
ACGFC25*<*B@H#!%1;8AH@@!1F%$@!'&+A40FB!&/96(;5-"=:-"1%+$F8D!4@AFD2>8#22'=A5$&*<</'?B
@r129
GACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAAC
+
A!%,D378"HA8?H(!+;509B7G,%F15@'3!#6:@A7'FBAD
@r130
CATCTCTATGAGCTGANAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGAT
+
G(?=6"8'07,G)/H6A8/84,2D3?>+?/#-+?D<7,H:4;:>A9C-A%!>8$E41G8(<3*E=%&B*!$7.97(6=7B%G=&G*5E4:$":"$99C>&?H)(CF9A'
@r131
AAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGNAAGGGGATAGTGCA
+
H:"9>C5"8D1'!?D;>-,1&/@0CDC#2>':A?:7+0EH"66+3A3;*"20:.AE),&+6
@r132
CGGGGGCTCNNATNTGNTNNNNGANNNTNTGNAACTTNTGCTTGCANA
+
*''"('%*!$#&$%$)%!!#!!$%"!!"&'"$$#%&)!%$$$&'*'$+
@r133
CAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGAC
+
$F:G!EE.5F"C%-@#+A'-G?!="9-@;7FBD+1+6'9#>7.<=""D#8'%?.(E&HCB-*DD.(5;BG=*@(B!DF91@
@r134
NACAANCGNTAGCNGTANGTAAGGCCAACNTGCTCAAATCTTCATACAGAACGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGNTTGGAGCGACAAAA
+
#)$'$($)"!&"!#+*(*!#$*+$&"'!!)$!")$'&')((**)%*&')%%$(((+*"***&%&+(")"!(+'($'(+"!"'"%&#("'')+"%$!##''&)(+%!%$
@r135
ATANNNGGAGNTTNCACTGNTTNGNNNNNCCNCNATTGCGCANNCCTCGNTNTGNNCGANNACNNCCNTNNTNCANNNCNNGTANCTCNTCTANNTGNATNCCGGNNNGNGNNCACACNNANTNGTTNGNCCATGTNT
+
""!!!$#$$$#!"!#"###""!#$!!"$"#""##"##$!!#$!#"#$$!"$!##!##$$#!"#$##$!""$#"#!#!$$$$$#""!!"#$$$"$"$!""""$$"#$"!$!#$$$"###!"#$$"$$##!"!#!#$""$
@r136
CATCTTNCATCATATTCTAGATCCCTCTGAAAAAATCTTCCG
+
#?)B?!$A0&!8?&B:@8,98;&#!,3;*?7F=7,98<C$$-
@r137
NCNGNNAAGGCGCGGGNGNANNCANNNACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCNCAGTGACACTGCGCTGGATCGTCTG
+
"!$$$"($#$)!##))%)!'"&$*$'$+*!+!"'"**)(!#$'!!"!"''))!""+%!+'!#&((+%+#"(*!+)#%&"&+*&++%$$%'&#)#+)#*&")%#*"*'**#&!*#$#++&(
@r138
AGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGNGAGACGTCACCTAAGCAGGCCCATAGC
+
+"'$'$#'+(&""!*$+(*'%#(*&'+%"&&(*$(+'&#$#"'"$#+%'*+&&)%!!&)#*(%&)(&)%#)
@r139
TTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGANATCAGTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCAT
+
0//<1@:H$?6"(')/*&-#@&@&?!?'?&9':1>G@":1A<CD>8)CA6DC;8.%*2/E49##?G0,(8%AA@4E2&FG,(=88=758;2!--+DCG61DD+B0"!7+=-977F"("2!#'06'61$#,A#*;E>B<.'83HFH*1+CG5&)276-F<&*@763*4
@r140
CGGCANACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCTCTCAGCCAGG
+
?32D@(>F?:@&-54/E84#2!BC>04*%8:HGCAC7&C1(1HHB&C$"%#-E';:(H4F+H'4)>>
@r141
ATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAATCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTT
+
,5E/+7H()G?40+=5:EH9>CH>-8$;A?@<FC-=!?<7/&G!0/$"362@'0.F/@A08AB92'<E;-<%CB"4"@#276:07)*3312,3"4?=C
@r142
TCCGCAGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTG
+
C""'A2*FE/%C2"5D@8A4%7$'8"HA=3=?$>E*(DDG&60+,2F5>AE90G-0F1$GFH6EG%G380:0'$/#(@7!?
@r143
GATGANGCATCCTTACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCCTTACAAAGCGAGGCTGGGTATTTCCCGG
+
-B=7@#4.09)$2=B3,?"2.5;,>8:5"#&>;C.,<+179B,"0<;4GC.+5CF;%>D+5($'779+1C4/$/%8@@7>>./<
@r144
ATGGAGAGCCATNCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATAT
+
*<C2'$=(@22*F98!1G&C<@9(A"*D)G(-40F;!>',81+16E'F/.762(.F/-HB5A1GCA.<4@,1-7(%>"A'=&;)19<4D"E+6%%<C7-$*&@
@r145
GCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTT
+
A:!>(8:H:A(<''D9.461H>1F*/0EB!=46CEG#(FBF,34*41%<EB'8B1$,A"1=22'3=&7*+2-!)4@.%<09-2B63!'F(A1-%AC93-?3(5<3
@r146
CNGTAATTCTTATTCNTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATACCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTNCTATNAGCA
+
7G,8:>B>C<318?@92C"3%C,:*+E4FH&73D:?(1>&<+(FC+$,!;"B3D>1>E9153@$E.*!4@+-,C;6?!H1F2"$1&>H-"'+ADF5F+#BCF14H453ADFE#"=3G%<;&&4?D
@r147
NATNAATGNGCANNNTTNNNNAGCAATATGCCATNTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCNGAGGCGCTGAGANATGGNCTTTTTCTTATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAANTTTGG
+
#"&('&'#!$)'#)!(&##!+'")'++!)""!+)!)!&!"("*$+)&((*"('%+&$))(!&#$+&$*!(*&(&*"$'+$"$"*"&')()')"'%&)##&$%""!''*('*+*""+%%*)##+(&$$(+!!+"'*+)#('#*"+'%%!%+*"*)''(*#'!)$%+"$#$$##!&&&*&'&&$(!#$)(((''#'$!#*!(*!)!#'+'*!(!')'()("$')%
@r148
GTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTGGATTTACGGG
+
>G@>5:!B.8/1&+75!*&*)5"&$E)-G1)ADG;<!+0*%G?42$(9+)EH3E
@r149
ACATANGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGA
+
99ECD3;5-#=052!3:F/*GCF.$&A*,38C<3C1B:>(;-F<4<(
@r150
GATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCAGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCT
+
9+839)5GBG,0E47F%4#G&E*93A,42B027$(C,A9/'=D&0;/9</0CHB%C5:>@46%*8E"%991+>8@#(;9&$1H2/!0<)&C98$)4E>64:*=0<6+6=A;E4/HF;?CF6E&?9B&C/B-7%DB4<)+.D348+$/0*1GEF?'C<??67,DA;$:E#1'&#$$$:H>%,'469&
@r151
GGTNATANTNNGAAGGCACCNGCAGAGTACGCCCGCGCAGATGATAATNANGGCTCACCTGCTGGCTGCCGAACGGCTCCGAGTCCACCTGCACNCCGACCAGTGCCGTGNTCGGGTA
+
($)%**(&*"#*&$"+&#"'*'%%"*%"#(%')+*$&%$&'*(()&#"%'$+%%!*#&*()'"!"($%*(%!*#*#"*'%!"*&'+!&"#!##(""$(*)#%))*)#(%%)&"&&%$+
@r152
CCAGGACANTCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAA
+
3,B=.)%B%4CF5H1(E@+H92#&/A,G24$@A4:F(+6'!A(H:8>.E=G,5&E1(2ED
@r153
AANACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCNCAGGTCTCCAGCG
+
4$@#C:A-,659481$330'C3H:(%8,G.$$==FF$9%#*%#5+A=E*?2530/,)')"9D9%-;0"8>H7090'"A4!H929<"3::<25G*'4."D+5>62<:H1)H;"7A9A'E.3%E?4;*'%98.-2.@'?05:/4H1!=+1/0)4A3.;=+9+7-7>)*E;33!C-+E'/,!0>$FG74%?!A7=69#B<D/79GD7H5/E.E$'F:B.
@r154
TTATAGCTAAGGCATGTAATAATNCGTAATCTTTTAGCGTATTCGNGACCCATCGTCTTTCAGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTG
+
7"!49.E)".C'9@EB83:2!0"/D%(@-(.G02A?;06<4"/014>-.0+'?-%96".!"A#;5A95HG).="51,%C@8?9BG/G'1?,)F""9&9G4;+F/!0<H'
@r155
CAAANTGAGGTGGGATCAGCGCAGCCGGATACCTCGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTNGTGAAGCTGCATACTGATGCA
+
$)('"%$(((&+%*$$*'#"$""#&$*'&#%++&&*%%'**%&)&)(#%%('$"'*!&)$$&!#(!$%"##"&"%%(&"%+)*$$)"$"$%%'"(!
@r156
CCANGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAG
+
429"!(!>E8/5-38B!8?7?953FFB:-)&"B%<@6G!*<@'
@r157
GTCAAGGAGAAGCTGGATACCAGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGT
+
@*.EBFFE8D!>1>.C*@4#;?A"'!/?$@#:H#=D9.58H,>.0F*27.<B35)#
@r158
TCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAAT
+
;BB".A&5@%!443@%9-$?:7;1F(*61$"GE$C420A,CD
@r159
GAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAANCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGTTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGNATTCACACCGACTCATTTAA
+
92;HA9D8D3@":HH795!(/,%5(;<:D%5"-.0/?-F$=D91=E5?F!:.($5+-.4*'E087HBEF,F@,27/E78>6)1&=8F)AA,;92C2;$>6G:17*$)@4:(.=".;F*2)D!/)&H#&A*9.CH:91A.,-*!.%@5'<'3GD>7!:B+&B"':3.;F'8;)'83#5*H%"&3G90A0"!H72B604,#D015F&'6<G7!?'.GCC1/$**0D"0$D20*;HC2=D+*("-&5B,D"3+8*4E'1F$'H:"#=)E:$=DC504.:*A.'3G5G=0B2%E681/9".)1A<&=B8*&":$4(F.BC.0@./)=1C;A8(1)&>%FC$FC&23#0F<A(
@r160
TCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTANGTTAAGTTGATGCAGATCAATTAATACGATACC
+
(+)*+'!"%$($'"&&!++')%(&%*&#(!#(&+$#&'))$")%'('%)+'&!%"")!"&!+)((%$+**'%+%(+$)+!+#%)*$%!('#&&!!*&)(*('$$#+$++"(%+&
@r161
GTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAG
+
5;E20*D(;3,1>1C)-&9=")<=H<D-D<):'+BF$1'GH=)
@r162
TGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGA
+
8(#=D/1?G)"0:G+3&6&/#3:F29867G$.&DGE(G-C3>/'94AA6+28"-2"@AC$=#D<)(=82'#?#,EFBH)211.!%
@r163
AAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATA
+
%.6$3.:A:C%A.<C+7@":7<47#'C"56#09G%4*#7#.>BF558EH>'A=+D)D?3992A(5906+-'$4B;1:-9H:
@r164
GAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCGGACATTTTAGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGT
+
A24>84B2>6&HC.7?9#H!;+?D*+@?5>8'D*.809$47"-,'21?$-,4F.)(#490&;(79,C=2'G=H*7B$HG>$<=76,#,FH@;5%C:4&%.B"C;',$F9'7!EH3?0=@2)'F/+?"0=>:?%!+$,4D0.!%5?</"31*3=>E<@:#.5',"E9F#<1;-H;6
@r165
ANGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCT
+
C2;EH$41H,?'43,3E2376*,0;!#:C3!.&E!(H0**!561#=B3*&0.2B"*G/8>G.FB-"0B)#503#A$B,H1%;
@r166
ATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAANCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAANGTGCTGAGCCCGGCCAAACTCCGCGATAANTGGACCAACCTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACTNGATTTACNGGG
+
5:@:6-$&6C=,=%16;@;AG><-0&%/7$#*E0142'E.D+G>0@45C?*</*/<;;3-6/#A%GE81!!?03@)F)$-DE(%4*F697"#)FE%-83F8:86G0'3:D+'=7*=68:@0:9HF<F*4@#,(:!=B%/065%7;7FBA#2&"A=(*&/>;&EF8+07.B&2-!"G?18@'4?A,5B<&;+H(7)0*3+0><$)-00((4>++H7&EA+%:)!9@@6$:&11!:&D5)#@D-B'1%<,A7#47>!#545AF7A"<0#"4*3,)&#'*">=@D:9:#*014/0C#/+5/+$9:5(953#>7C!*D60G2=!,;5C$G&,+4;(FH"G8!2:-*+
@r167
NAAAATCGTCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAAN
+
!3-87;>*$$*8%F#G?(>38<;#AF10/$%>1**9A3:%!?F!6;''5>D-F=%?449E*C.+<#%49,>/&)@"9CF-F*1DB2?>G-%?!66)?<&4@4'".@%18/#(C?<F(7.G1<B-!D*EB::.$=:D)544*3*F#395G:&5<
@r168
CGNNGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTG
+
64/:59HGGB?E)%?,35H,2+="3!2'C2;*6<GA<6+=H.D?A2='158).)/(#+(!7>CA90),+1G&E$B*H-D.6BC9.1>;G*0+B455A0%(6/<(<&//:&2=-)49C>9!@260%C>B?#
@r169
CGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAAT
+
*=C73?.A*?*8=E8-CEB-34C.B64-3643D96=FH*G>G&$:1)?5.'$84?*3.?#&27;9?E!B!2=C&G7)@7/8:&F/(A*E&7-A()!9$6FG987;?-0&F-560A'3FF%@>A$5<")E4$#A!%HD>$/800%/"</G/5,&!D0@/9/
@r170
NGAGGGCTGTTTATACAAAATCCGGTAGTAACTTGGTAACCAATTCCTAGGCAGGTCATT
+
%(E''8F,=+H*4526-FC/=G=6+2!$F0"81*987)1)4?+&!=.&%<=9.!*5B)DH
@r171
TTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAG
+
B4B'6F0?5*58#*B32%4%/97=;+4$1;;<E<6+>6<9=E%9,5D34B/2;6:C#7?2*D6)+7B/@B+.D!G";B#%C
@r172
TGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAG
+
?/0F47C0G*%8//&%<*>-4+2%,H21/)FBH>%6:02FB52AC#6'>&$(6CC"-9%63B%@*A!F/F)>G*/:=
@r173
AAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGA
+
*$C@1&=;C01!83,1EA6AB6.E%3F')*&25&3D7<H#-DAC&B&)C:H,:4,-83)%!$B'*74A(4!6&H<=)D.13DB/*!6<><?"2G@<9FD"
@r174
TTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAA
+
,<6D81F-FE%@58G-4@;6B4C*<<5<:B13G9*B7-?/.D,&.
@r175
CCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTNGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTNTTGCCCTGCGGCTGGTAAT
+
2=#C69=!+"":<<4%>1C'?$0!75!):.<2,$+9-;C)15(,6F%$:H5'E7!@G4DG85;9#:#.&*7!!+?>"4E4-+D6+/H%/"@)==(+4#$;!%F/HG<!&14#2B&,:*?,%6-'*C=D,G?H=$<%.+H77$
@r176
TAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTANCACGTTGT
+
%0$)*+/2,4H@@354<=;(H@GA)9G62+;5-.H2>'-8EHD"?#H2G!$H779%!>
@r177
CGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAG
+
9%#B@E12*#DC$.+B%<D>,;!-<A97*796';:;@'54.(E"%(G4*?@)F0!=="7HH=GC&!?$86C49@,:86"<,7+6F-9->=4EC8.F<@;'#D'$-85HB1@*7B;%?G;=54#(=@='/8#'25G,?5?!,*G3EFA->'2@3D??192C=)A6/5=4;9=HCCDC<<D'E.94B6EB!H#,G1@@G@G)3EF?F
@r178
TGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTNCACCGTTGTTCG
+
3B3#?")!>?28%)>96+D59):?B31!9>A,A#3)F&+-.$)?HA5G%0?+7;1+0DC/=A.)+)A>G@.#<B$<5*5C3-&A'2'-9E=;=HD)@$'9.)HD:A?$-)#6F918@DB>/G10A8(,$.F#<+0&@;55%E;=#B6%>->'6B'B9B$;3A<4#G;%1FE8>1$E-91>@!':8:$$)D9#1)129C"<F59,?;3$8H,-)F((1&87.8,(/3.>G,23E>84D@!E7#C6:B,>289B,C)3/407%3##B%.?C">,6C3(?"H>
@r179
ATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCT
+
*4F#($&.3#H'&@8.*4@E8#+%@A!H,1E4?*3C9FA".0>@$/)B8D*DC1:)2*!7%$3?<7$EB!C?3)1
@r180
TCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAANTTCATTCCCGTC
+
$;#(,.(21"F;AA'!CEF,9H?9FFE2$4;/+<;&&&8.D.B>@B#+>.51:.6F;/&%@%.8@E&,10
@r181
CGGCCAGAGCACATCCTCAAAACGGAACGGGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGNAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGG
+
8#H"!9.-.2'79AC!7-#E3-0H+D0298#3*)5"G@AG<$255;H):17<"'2647!)8G##9%131)61;<$B1#*82;1';H!?*8#&*9%2,:%>D-E)'F)%3@;;0-!H=#&;@8.C@4D-(/A:2++*@&/));6G@&-&2%:779*2<$</D32%#F&!8=>
@r182
TCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGNATAAATGAGTCGGTGTGAATCCCATCA
+
+$-8?!,DF#A>'*($.H93,'=-9;!-?8%)@9.5/<&?#)%$F4=0B65$?DE84:A(7#6!
@r183
CGATCTGGTNATTTATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATG
+
AH:(A9&G-,<+$3"F%"64(?%%&GF*"+D)@B.)8'$;$+G<27+.(F7@
@r184
NGTNANCTTNTTNNGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCT
+
#($#'"%%!"&(#+'!$*&$''!('+)')()(&+'&*)#$'(+'*&((*$&%'!'#&+%$)(!")+)+&)(&($%#&(**##)%'")'&%+))#'#
@r185
AAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCNGCGATCCGCGACAGCACGA
+
!:CE3#(H=4C<'*%B@<%71*@1(8C4)%8#?4#0F;;>9,#AD$=6=&0*H;3%G;&AF=8%G)E'+*).B3?
@r186
ACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGT
+
F:/G?+&.=*6*B()F1-BFCD$(H:%2';&AAF#@'.9A-.@B>A.4"CD>04A.7F19+32."2
@r187
CNCGAAGGCGACAGAGGCTGCGNGAAGTGCGTTATCAGCANCGCAGAGCAAA
+
%)*+))!!"$+%"$&+*$!$%)!*+&+$$$!))+*&*!&#&%)%&%()*$!$
@r188
NNAGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGCCTCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAG
+
'#'&)$*+')##+%($#*'*(*)&&'+!))(#!(#"$$!*&("*#"+)%"')$+$!+%%*)"!($(%"&!(&*##%&*&+*($***)+%"*+%"'&&%*!$$(('$''!+*+'+#++*)%*(+#**(#""&"&+%*"(')#'&)#"!*$+'"*&))*
@r189
ACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGNCTNTCAGNCTTATGCTCGAAC
+
*+#%<-,=,"*E3*6-@2&2@C%7@>09<9'%8.'$:F0-8;%&H/2368=A-2>'=
@r190
TGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATT
+
B==05/86(C9F#/@A4+<94&98A49=*GE'0EE9#:#'/<-BAE*?3@<:'
@r191
TGGACAGNACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCAC
+
BB-224!(3$)*F.7*!#H$=))#?6%'E36=;4.,61(F&E
@r192
TCAATGAGTTAGAGTCTGATCAAAAAGATTGGGCGNTATCAATGTTGTGCAGATCC
+
+DB&6*&>"$:,9*%D,==D7'"&"8#,=.D<(388+($4!&9/C0)"'E",2H'-
@r193
CTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTAATTCAAAT
+
1C7#5C<.;&B%1))"0#4F#.;41E%;)9%EGCB#8:?F3!33F?G6'C9G;F7*12F;5:).-:4?5<13*5,5H83BH8!@+'1B*G37@1/%7196.)B"4)?;*;*1<&H68&7+&577,,9F1*9,E%:8</1*F104D=22+<@5H#:.E*&,9<$=2C-710)&:
@r194
CGCGCTTTTGAAGGTAACGTCNCCACGCGGCGAACGATGGCCTCTTCCAGCCAACACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTT
+
.D-"B<6/>*1$2H:+E!!')H$0H@C#G1-8<$40/G+)?-;(?1$$"7F49$58%*69@49)@H,<3(DGB'5B%=,9?$'-:'6//4#*?E6A
@r195
ACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATAC
+
H3%99A)G3597+4/5#F;E1;2F8+7'0@%*C/894,C!'9D!/!*99%+!
@r196
CGTGGCCAGTACAAAGGAGGCACNCACCGCGCTCAGTTCGCTGCACTGCTC
+
C<*5:G=>8)7<4#7&&@2?4+'!#G;52C=-$?1/4=C3.GEE/<B//E5
@r197
CCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCATCACCGTCTCGGAGCCGGAGGATTC
+
9$/,E0-8"?:?$3!-6%(306!4C.!F#06?$F+G>.&11E&#53=@+E/2%26:F688&):616;C"HF2@D/D6C2;G&?%><*<)&8(03>GC7+)*3-%@-90)$F+$1F
@r198
GATAGTGCANCTCAGCAGTGCAACCAACAGCACGTCTNAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATG
+
+";7F"FC'/A!7.C"F@,%<.+*@'$=(D-6+:*0C+=/')A&CHH935#80-+7$=4?DA-G!?$(C)$*6,(7>'C
@r199
ACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCNACTTTTATTGGCGATGAAAAAATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCANGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTNACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGAC
+
2$(3,2&;#589#</=+DB"275<?38<"HD<7,2$<D)0#2*B%G;$-'!/2&0$G-*626(F/=7AF&*BC9!HB(B+4"*;20BBHF@-,$75.2+2;G,313%02H.=';FB4+:-C(?FAF=0!B"2+-<-<.;;>7)*%@3C3''"417$%&0;/@F;030;B-AF905"A'D)$F4'1@&@D*6',2*'C?FCC-24FDD-,425@@F0,AF@=4<FG*H(0+B(E"*93=#4(D3>,0:#5-*38#4915421G.90*9CH)A'"51G$@8:44:.G*'@F2=8%DD738;=8456:)H0A16+E3GH.C7#905B1@=H+(,0/4,B$10G*E7
@r200
TGNCGCANCGNANCAANAAANNNTCNNNNAGNNNNGNCNNNNGNCNNNNNGNCNNANNNNTANCNAN
+
$!$"$##$!##$$#"#!$$"!$!$""!###"""!$$!"""#"""!"##"#"$$"!#!"!#$"$#!$!
@r201
CCNTNTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATNATC
+
'(!$'"+'&)'*+#(#+")*%!$)$*#!$!%#)#%!!()(+#(&&*$+()'*%
@r202
NNGTGNCNNGGCGCAGATGCTGGCACCGAAAGCCAGAACTC
+
!*)&#('$"%+$%!$%&(!!+)%*+'"$$!!!!"#"+%$$'
@r203
AGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGCATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCAGTGTTCAGGCCGGAGCCACAG
+
(=H0D(H(05,:@55+-03#)F=CF,7"=&*%5>>C$@CHD.:,7HB&)?>!FA7'"%<%+&+CD>#)43;/&$/-A8C"%30-&%H?6:H4*(+6(;8-$F4E351<G"#+#01619%$$,AHF9$C$(%?,1<B:(1"8'+F,7%(D%4.AG+)21F4)8#"3":F)..@(3:."A41
@r204
TTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACATGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTAACATNTAGCCGCTTATGCTGGAAAGAAGCAATANCCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATNACTACCGATGTNATAT
+
:A+8"H8#2(B3"+5(H2)3EA7+B'/:8F'*AD3G'$-F*5;#A1C>#4D../=&H"0:/E,&#=0CE.,?EDDF-G78)+446D85,2"C;F/#.))7G-%7::=E":!!&FC!;(5;B?,?=89,FA6>:&;H4:3A7+4A0!"/?HA>BB$(;GD+9<=8H%!-<$8(:/9,47:3($*G@40);7DH7;9;&?+6#92@*;=:$604)>#0*!>$@F;4$6B'E.,+&8-B?D5H(;H
@r205
CACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTNCATCCGGATTCTCTGAG
+
(:<A3H*;%D6343B47')/@;0FA("AC?),;-=D03*F#"4>03$&7D,<#G?%70;30F
@r206
ATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGA
+
*1H#:C>(6??C"4A*!8571#@=56F256G9(7AEGG8F%649"?E-FGB:70)42D49:8!402!D0CF3*#%
@r207
TTGCACCTGCAGCNGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGC
+
-&-#E(C<=#5F!5<7)/593F5;3E(%410*C@E@!2E'*?,H%?D5A-*#"*F!*8H)4D*!9C@(1
@r208
TCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGC
+
1$'73?7=/0(&(A530)CB*'?@>+4D$;1486%F=6>E4&/$!:!;CHA3"?7(7#G
@r209
TGGCNCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGT
+
E*H&7C?.?0?76!)2E,A5*:/',$)H:>">#.+:@>,*%001
@r210
GCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGG
+
45@'#,28HCC'.GH/11!09GE8@254!.B9#6C1;7:D=+H7*9,E6E&/D105><
@r211
NCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTNGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCTAAGGCTTCACCGGTCATGGTGTATTTGCCCTGAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTC
+
&*1('H-B9@&,*?&!5%&G),"'FA%#,4GB'"/4C8>9$4&,F)B'"(F5*1?6:-,5!?.+EG&;/7?<%9+B-24@+3++CG5!"0'*)*'G$+E(GB<C*3E#?'>&%.G8?<#%A(-2:BFD1B#<44%2*(*):/A,->*!40#2*90,2%$C1;0.34<.:%#A9/(:<9B<;53?-2104!G(/D'G';&77*(&HA>1B(9DGA.<-A(A>.+?AH/6CB(?
@r212
AATACCAGGACTATCCGTATGACTACGACTATTGATAAAAGTCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAAT
+
A'.(6B2@+A-$F-<@0?'F?D"F&9G$,-H&5'%..=3.;)=(*!.@*=@E@;#HFF7/C@632,2+)857H=979;AC7#C7"-/4
@r213
TGGCGTNCCNTNCTCGCNGGTATGTTNTCCACGNAGTATGCCGACTGGCACCGCNTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGNTGACGTACACCGTGCTCAGCCT
+
$#&"#%$$'&""(&"#*$)*!'*((!!+()#"%+!%($$&$$&+#*+"")%$!)#%''#!'""#!+!&+)*&!$+!&)$"#%%(''%+#&)#+%)!($)'%)+(((!+#%'&'+!%#$(#'()&''"")+'
@r214
CGCGGAGTTTGGNCGGGCTCAGCACGTTACCGGACCNGAAGTTGTCCTGGCATGCCCA
+
;91#*,2%%+*#3.=*9/'+<#%)B9/(B9EF+*9"<.C"A!,+:/.7'?).<H6@6"
@r215
GTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATAGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCNCACC
+
=12>(HE,&G@1G2');,C/2CD&75@+&7"A?(>A.?B*/G<&D::;;"$/>.@0(;5F;AE01:>=,0C?4):(B./(4?=3:D>D+0+%&&E5"5*+/D,E:B)F%EHH**40C4=AC?)+%2'$>:HH@%D801,?6=F,=31&*E3!79,23E7->8&H/+"G"G(/@&,:=#,+$H)'+;&*5<&!7*"=6,=A65,@8+%G,-H!!
@r216
AAAAGCGNCGCAATGAGGCACTCGACTGCTTCGTTTATGCG
+
B2+@C541-+:H0-EAG@+G)H/9$E'"//@-1?@/$(%3&
@r217
ATCGTTTCACGGACCTGCTGGGCAAAAATTTCCGGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCNCCGCTTCCTGAACNTCTTTCAGACCATCGNT
+
'((EG37-&B33H>H91GG49!EE0;=5)$9$3@*%$A!=!H*>E-1*6E#%9?AH;CF'A357((%"-@H%6E+=(4@9=E.3A"H"23!@':":65*@3846)3/.;!+@=%B+""=$<F(&C0)08'1
@r218
GNNNNANCATANNNTNTAGGNNNTCTNNNANGNCNACTNGTCNGCNTNNTATAAAAANANGNNGGCTTNNNCCGNNCNNTANTAGNNNGNNNNNNNNCANNNNNNAGANNCNNNAGNANGNCNGNTNNNAGNCTNNAGNTNNNTNTCNGNNNNNNNGCANCNANTNGTNNCNCNGNNNCTNNGTNNNNNNNNANANCTNNNNNGNGGNATNTGGAAGNNANTNNANNNGGNNGNCNTNCNNNCNNCNNCCGCNNNGANNCNGNNCNGNNNATCANCTNNANNATGTGNNNGNCNNATNNANCANNCACNCGNCTANCACACCNTNNNCCNANCAGNNNGANCAAATAGNTNCANCGNGNAGNNNNNATNTATTTNNGCNCCGCGCGNANGNGNTNCCTNGNNANNCANNCGNNNGNTGANAGATNNCCGGNNNGNNNNNNNANNNNCNNNCTCNTNCANNAANNNANCAAGNTCNNNANNATNNNNAAN
+
!""$"#!#$"#"!$#!##$$"#!"!"!!!$#"##"#"$!!$$#$$!#"$!###!$$!"""!##!"$##!"!$$#"##!!#!!!$!!#!!"!!!!"!!"!$#!#""!##""$#!"!""!#""""##"$$#$#"!##!#!##$#$"!"###!!""$!#"!$$"!"#!!!"!"#$$#"#$"!#!#"$"$"#!!#$$"!#!""#!""!"#"!"#$$$$$""$$!!"!#$!$$!$$!"!!!$#$!!#!"###""!$"#"$#$$!!"!!#"#!""!#$#"""!$#$!!$$$#!"!#"#"#!$##!$$"#!"!$$!!#$#$#""$!!!$!$""!"$#!"$#!!"###!"#$!##"##!!#!""!$!#$!#####$"##!$#!#!!$#"!$$$#!!#!"$!!!$$$$$"""!#"$$""#$#!!"#$"!#!##$$"$!"#$#$$!"##!"$#""##!$#$#$#!!$"!"""$"##!##$!!#"$!!$#!"#$#!"$$"
@r219
TNCTTACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCC
+
&!($'))%*$+&'(+!'***&$%(!)*++!""%*#'!!"&##!$#'+!+)#(*)!*((!')%
@r220
NCTAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTC
+
!03+2DB8!0(8&&@,!F0/2;707G6(E5E/4=@6(?B.@
@r221
NNGNAGCGAGTANNCGNNNGCANTNNNCANNANGNGANNGTNNNANNNATCNANNCNNNNNACACNNTCNNNTTNGNNNNNATNCCTGCAGNNNNCGCNANAANNNNNGNCTNCCNNANNCNNGNNGTNGCNNGCCCNNNGNGCCGGGTN
+
!#$#""$$!#$###!#!"!#"$$"$"#$#!!#$$!!$!#$#!!"!"!$$$$""!""!!#"!$#$$!$$$!!!"!$$#"!""##$#$!$#"$#!"#""$#!###""#!""$$!$$$""#!#!$""""#!"#$!##"!##!#$$#$$$!"""
@r222
CTCCACCACTGAATTNACGCCGGNATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGANGACCCTGCGTCGCCTGCCGGAAGAAGATCCGCAGAATCTGGCGGACCCG
+
$<&:>17+&8-7>-C.@2E>D8D='?+,&&.8=(12!G72,"4*")!>C/EB#?A#1'F"#+:*@;8%+ED#*$-0&)43!4461#%5018*0H7@3'!)"14D6E"4)
@r223
GCGGCGTCTGCAGCCGTTCGTAAGCCTTCTTCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAG
+
#*,0@C-BB;'<&<&5(;<F;3E3F1/,&0D<08A,3E9=493449/;>#H"E0;.:</@<"4=+-'?F>&46DC01'CG$+;A:D*CG.B,':CECG<C;,>41+ED-:2D6.CH.'@4@8-=44.';D8/:<!!!C*#BDB3*24:#4F>9?G#(3;1?(1;0
@r224
AGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCT
+
;%5"E;;'+3$#)71"+)(3-3&H-**-,9)B%%C!7-C?H(H8EB
@r225
GNNNTTGAGGTGCCGCAGCAGTTGTCCAGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAANTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTT
+
**#$+"(+%!&))!#'((+*)$#%*&!+(#($$&!)**)%*((#%*+"#)%'(*!$#+())!!$+#+*($%%(*")$)$$&%&&&+")$)*)''+%"($&**(+%&("!$*(('%$"!)&*"#
@r226
AGATCATGNCCNTNTTCNNCNCGGCCCNNTNNTTNTCCAGTTTC
+
&%(($&$("*)#$#$'&""(&$!*)&$&$(#'''"#")&&&+&$
@r227
ATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGNTTAAATCAATTGGATGGAATTGTT
+
3:@4&62@*$62AF@595"142/3030G:@61,;7GF"=#A68969!=7BH)?G)*:9(,,+6-6+4D>,+6'#G$F!7F$14+@9AGD2A4@6
@r228
TTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGTACAGTGATGACCGGGGAGG
+
61>(F&7%&$31$;=B%1B>%&<8')//;25%B($:0@H1B&+FG55DA*=HG
@r229
CTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTC
+
,-.="HG$HB6*:)"''CB@*F#?0?@>E<=8F%.(2!.&)!B=1+,5?
@r230
TNNCAGGNNCAGCGGAACAGCACACACATGTCGCGGTGGTNACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCT
+
%#&')!#&+!+!#+!$%+&*#+)'+"$)(("$(""#!'!'*!+()#%#+%$#!(")+!%'"**!%$$)&$))('!+&'")%$+*"#&%#$*)&(%&'!%(&''")**"
@r231
TTGAGGTGACGGGTTAAAAATAATATTCTTGGCAACCTTTTTTATATCCCTTTTAA
+
**;8%H<;?5<B;"??;'.+1%AG67E%35A)%A%2+5B%)>,E60H$(C++A,6@
@r232
TTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAANTATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCANTTCATTCAAAA
+
6:1!1+E!0"=0&5+145;!1>0/,=9%!<'9232%&#9163;6#"#<6(8,31E</=:3:@&2GBEC1)1551=?*<H+0<?*&#+!:)8@7:;)G"0+,?6#3$C1-E#+'9&C!0=<C=.A.:B%G<;G:>$8%@!%F72=>?B"2:$%H#2E2HB50?$35>E;$E$>/=,FF%4G.(A2"%2&C!D>(8.37!;C,!>)+%H'519*0$!/1/-77%>&G%-)$'8F0:3<<2!D>)+E&,A)+!"$;%"3-
@r233
CGNNNCNCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGNATCAATGTTAG
+
#&&"!#!*%(+"'"$')(%+'!+)+!#+(#'$$)&"%$**%'"+*)&((*)')
@r234
ACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATNTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGA
+
B,%C;5C7"==6<2CD6)*G-#26F@!":B#:?F=',C9F$6*AF#G6'"=68GB4@3H-)G)D3723$'<*F/-C
@r235
CGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCT
+
C759G8=))H/0*'6/5A.*=1E802.E')0B$:$3HC3+<?B@58,@5'<)=H!A.DD:;&=%-(13E@06H9G/)H?G=06E!;7E#H2;+HD:HHA7H.&;#(!*6F+3#(G?@7.014(;%G3+:$A.E4AD6.*.-"G.8G%43A/@E%69>>BA009A66B7%5+(%8?74%A5:2)<A629@9H<(
@r236
GGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACA
+
CEH!#9(C?%B+,=#'#C&09='4G>!,,99.81G3<=C04#/,8!<<=:%(:+C2$2740
@r237
GCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGA
+
/9?67<<!+@!4F12,=B"30;3-HFF=&9,HF/%&H-&;FH5:/0HC3@;,-,*
@r238
GATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCANAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTC
+
$C*H1?<G2#"9),;./2)BH+<18E*%E=-H<.(88/&+=3)<*G1F:1:63<5G4D3B-57AG$,>12?C7-F/C@>214BGGG34A<5.$365G!H#B8CE8B:@647'6(+DH$C5/>..3?0#-@#:%)$6
@r239
TATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAC
+
*<,";0,5&$.@1,6B32G;")>+,!90$3'..@/5F<:,
@r240
NNNNGCNAGGCNACCNGATATTCATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTAC
+
!"#!&&#'"*'!'(+!&'&#**+#+%(*#'"(%"""%"+"%*##)&&(*!#(*%#*"+&*'"$&%"!
@r241
GCGCTGTACGTTTCGCCGATTGNTTCCGGTGAGGTTATCCGTTCCCGTAGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTNNGTCNCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCAT
+
=GC/"//E,,85G*;/D!/;7<*D30B;//14227G8/1*2#F@7(7%%+'/875:&77C/9:A=AABA7D2&$H0"E(/)&6G%CH4?,&2%@/;%<$.4C'DE1-*2*.,.#2;!<%-+!%B,#?%C1!>F5",)6H4/#?,+=G-!H#C!#)CAD7><7HC03&<+!7.*4>#7&+DB9&"B
@r242
GCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATA
+
6A)$:87@*#:70),8#3H)1/#'H7;&%+!@$?"7%*8:@(-5,>H,@AFFB@'"*D=?AF$5657A&/++*3='<67=*16F.A#C$"H@,:4G7+7?D,%D
@r243
CNNNNGNNTGGGGTAAGCGCAAAACCAGTTAACCGCCCTNTTATCTCGCTGAATNGCAAACC
+
(!#*'%*+#&!+"&*(+)%!#)!(!%(++%*&&%)&"!'&#"'##&#%()(+&*)+!+%"'*
@r244
NGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAATCAGGCGTTGGTGCTTTATTTAATGGCATCAATG
+
!7'F:,C<>H'%6(C(F)+ED#-B45/?'F=&0:%>=4=BGA?G@F,+B&D:9#$.>2<@%!G9,)E8=5A.G",BC#416G3>-%"39>;$()4H-;(;3
@r245
TGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTAC
+
1A*+;7(?H?F19=4<($"3G4$7DF&-5?->//'B+E.9117!=+#5?-993@!?C?
@r246
ATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCTAGTCTGACT
+
@F8>B9?70$:HDB0;2A.4<8%&!?&B#!49C(<>>62B/CA)C40G<24
@r247
NAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCNTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAAC
+
#D?"/$H",33!&1&#3?"-#C/7,D=32AB)-%,?6EAHEF#;"%,-"1!",)%/.3*E8<#<;2E1H+20$2+5,1$H')%'E875*+:47GA#D7D<@(1:5=F@G)#(:?06#D;#?$@E1&&F:@=
@r248
TGGCTGCTTCTTTAATCTCGATTACCACAAAGAAATTCTGGCTAAAGCTCTTGCNCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATNAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATC
+
G($9@8D-3,#7%$EDFFE/6'43G6,'52,8$B4,"#=/59:>.!+FG)0>32C0$+=:%'HGCD8=?@FC7*"?.-)&7;D!@2+(H/D1(.-G;45.>1<"'@D"+#5H:$/,5!@#(G>F.+931+H"4?4A1*@,8,;A#A-540G3")+)13:!EH$@*!
@r249
GGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCATGGCTGTATNGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTACACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTANGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCNGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATC
+
B?;B6@:>G9#+>FH>.;:=D7B>A$#)?<1:<(C0&49?423@;%2+!$$..?.,<F$=)C%:???F/41FF4)*,(*F)/*($'D@BF)EC.7)+'</6A8!:EA<02'.+,%'/AB$1*C9@*9/F?9('4%$E)>5AAGF#19/3*!+=(116"0.3148!320;439"7/.&EH"+ED1)(@1?17HG7<@9B-(7D,0+58B#>;4+,A@6EF/AB;7F<=057&)3C*70F=8;BC,@2F?D9C8,#03**+3!7!+1;6$<ECH0;4'?7&$
@r250
CGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCG
+
E@;E'&%-4@!)5#.-9D(4%E=!C:C<.4")"""!*F!(A=((2D8-10>%@:0
@r251
GTCAGTACCGATGTNGCCGATAAACACGCTCGTTATATNAGCGAGAT
+
G;5/FH7&53#/,D386)6#8#5"?B)87A:<?1B5<4"G(2,*"'G
@r252
GGATGACGCAGGCATTATGCTCGCAGAGGTAAAACACGCTGGAGGGG
+
'092;G/.@4#6!51&CEGC="!*76</1-E@B%*-*95F%D1"0;'
@r253
TCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCAGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCCAAAATGGCACGGGCAGGTCTTCTGGTTATGGAAGGTAAGNTCTGGCGAACGGTGTATTACCGGTNTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGANCCTGG
+
3&1&)E"0)3@(:'E(6D*!?'$4/E"2<A<H)0H)&+#'/:;B%;@9H-?($<2@2('A?B::+6=/8H6-.A>"'!.-08AC2%0,!G8@!31/-)7?94>;C/7)8+FD!G%:DB+6>D0E0'B'C(!$H42236<14.>/D,++"7?4DA#G1:24?'?G?2*5;!(F/6-%4?4<70.4#,@H9('85='=5-<+D9
@r254
TCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCNGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTNACTGATGCCCGTNATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCAACTGACAGGGCACCA
+
8%;:?)4$=,.EA.)3::D*32&)0@#&1FA4,EA"4813"G?D=D+$,-E4@!3@D6@H;B&-&/7)1<6*00#6+@F0;@>$/"$4?D#0=::D4!2.B5404=)-""7:22G75)>.*;!*;DHEB8B+=A26&BB=&"?7B3$)BA<!@H0:)6-6!*&@GFD&&2>$D9-+G+6%A%9G8/!*F""?0$,8;,H9$3<3.$3+9"4*.#(:)23521*(#+4?C#%C/G?8=;)$'5D0**-/<7<B?%.5A'$F+?36"@?'58E=:F#>CF2-<$
@r255
GAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACANNC
+
F5A*)-650:?*818A*-:?=G&CCF&28=-!$0&.&&/#F8B+CH2(*?C#;#-<E<!.='9A%28-)CB"?:@4*5$29C6?9?/?%E)<:2H/E5H)/C.&=?*H)(06#*AA!0A+8(%E5BF'DC=GG(%
@r256
TGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGC
+
<69C$+'$E&@8+B";&8A6+@.?H/9H=B,%:HG:@HE==D&*D(+'E=<HG+G#5
@r257
GCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTCGCTCCACGCCAAAAGTGAGA
+
;+>6(9&5CH*H&/"AH!A+0+5/2$)+3HG846&5A#5!>.!D&H8A@&?H>)97A1
@r258
TTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGG
+
.!:-@04<$DE7GD8:58!@%@;:#.#C#/G:=)'"3H.6$*('::;-
@r259
AAGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCAACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGC
+
*!::00;A#@<;642G*F#31%;<C'(/4:"B:96)9!#F!?03$3&=):EG"*520!?7G6B=%#G('$=80:.="F=#F'6G9AB311@)F64:86E@*35%;:,HE0+*9A#3F+/E2;?+%EG0
@r260
TCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACG
+
?3,7>!D39<>#?9722*2"7,G,=*'#/>?)7C!)4D$3
@r261
ANGCTGCAGAACACGCAGCTGCAGACCGCCATTGTGAAGGCGATGTATGCCGCCANTATTGAGAGTGAGCTGGATACGCAGTCAGCGA
+
%'+)$""%(+$')('+)#$%"!!(%$)!)#"&%#&+!)&#$!&!($))!*$"(&*$+'#!#'&)*$*$'''#)!&+*%"+!(((*##'
@r262
NTGAAAAATGGAAAAATGATCCCTTAATGGCTTGGGCTAAAAATTCTCGCAATACGA
+
*$+#!"%$!&("#&*)"+%*!)"#''+$()$$!$%&)*$!*"+&*#)&'#&&)'(%$
@r263
GAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCA
+
,!'(0543F()<2@%#-C/#<$<&,B'(<B.7:*3A%8%8@BA52@-"F9H=<*")-C
@r264
TTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTT
+
,G?*#A':<A/9<0!=1BD8@-A29;>*E<1'0*#AF&C8("E!E:=%%?@?$8AH
@r265
CGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACC
+
E&H&2"%&;-@!#"*=/1'@-#:73(.&*$H'40>:&B)5*C1'A&,1>417G8!+AA1+"5&7(GF*!4$=2:<+.<'+E5@
@r266
AAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGANGCCGAGAACTTTATGAAAACCCA
+
3@?%+@4H2#@0.22$+4=%$C>3'/F"41:A;'E,/@<=3<$A$:<!8!!.>$7@&,3A2-<!@
@r267
GTATTAANCGCNNNGNTCNGNNNNTGNNGNNCCNGGGNGGNGNTGACGNNNNANNGNCGTNTTNGATNCAGNTNNNNTNCTNGAGTCNTTNTTACNATGNANCACGNNAAGNGCANNANANNCNCNNNNNTNNANNGCCNTNACAANGAGANACNNAGNNCNTNTNTATGNNNGNCAGATATANAANNTNNNNNNACNGCTAGNNCTTANNTGNCGACTCCNCNNNANTCGNGTNGCGNANGCANACNNANNAAGNCNCAANTTNCNACGNTTGNANNGANNGAGAANNCNAAGGCNTNCNNNAGNNN
+
$""$!$####"#!###"##$"!$!$$"#$$#"$#"$$"$#!$""""##"!!$#$"$"!#$!!!$$$"!$$$$##$"#$!$!#"!##$"!"!$!"!!!$$##$!!$##$$"!$#$$#"!!!!!$$$#!$$"!!##"!#!$#!$#$!"!!$$##"$$!#"#!!$!!$"!"$$"$###$$#!$$##!"$#!$#"$"$#$$!#!##!!#$!$!!""#!#!#$!!"!!""$##!!"!$!!!!!"$"$""#!!!!"!!$$!!!""!!!!"$"!!!$#$$$#$!##!!!##"#"#!$!"!$!!$"#"!"##"$#"
@r268
TACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCAGGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATG
+
<G,#GA1E,E.,C?D&>G7+EA&EF3)<+(D!"-*E2>8<+%7$@C",)-#G?/@/B,.*59FE)+,,*D-)F#E9D<"1>DG-07/40B**''2A60&G:'?B/.E/D4F+-FDF%(587/2/>7*3*H")'HEG?,.=A-A$E:2*)4'/=&B:?;DC-F12E"9C7D>'"=4#%BE==9E00+4;84$'2.,-B4%H
@r269
CAGTCTTGTCTCCATGCAGACATCACGAAGGTTTTTATGTAGATGAAGGTATAGATATAGAGTCNGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAG
+
",*-"5D>=B&;-08>E",--A'($5#0D/@9'C7#2.*;,C#>@D.G!,*>#28./B5<=%);*"F2#C*&-#-'@'>D-27<:>07D$H'86<A;7=-6"!"E
@r270
TTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACNTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATC
+
@.AB;9-;F@8"9C*'?1>(#-.0DD$:/)37E1.!:#9!@5D!7?C"(987.*GH&'(3@C8/F4B27138$!:.3E6H$"9;,>
@r271
ATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCANCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTT
+
GD="A1DAB-.G'3@>&2'DC?=A6%C*3)34)!:$!(5:0-:=8C-40;:C93BF0B11-#AB:"<;'<=%H'&2#-AH?=
@r272
GCTTTTTTATAATGCCAACTTAGTATAAAAAGGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTATATTTTGCATAAAAAAAGGACTACATAATACTGTAACACACAACATATGCAGTCACTANGAANCAACTAC
+
+)'#"#)+(*!$!"'#+&!('(!&*$'+*"!'"+('"'%**"#*$)"*(+")("''!*"'+#!+'&((*')(%"#"!%""(##)%#*)!!*+$$&+)&')**"+""#%)+)'*!!**%*")&*%#((+&'&*'$*$++##*"&(&!!%"
@r273
CGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAA
+
G:'*4&2'0C9%=?,GA%H:;D=;:B?!!2D,3+D08E+5)(>8?,-<2>&E/,?#$7#57"$G/8@#(1#+?=2H,D#:>H)<B/60>%E&6H@$4BA.2D0D@")*D26F,G&"A&
@r274
CTNGCNGATGNANGCANNCTGAGNNTCACCGCTTACCCCCG
+
))"()!*(#''%%#(&!!#&'$!#"+""(!%((&*"'$(()
@r275
CCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCGGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTNGNTGCAGCCTTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGC
+
*D@<9*$)H-1@BE2@A%G?G1$147,(G46316F:#"$$B;?G1@';0A*#8(0#B;/><E#C/4,,*<=?',81,H)-A:,2#+E;/@2&;%BE?1*@@9>$.AF19&14@6+G6/5!*@G>1:)G)/5/)("&7$"C%0-7!)$),E',F(+=E+*!DG1-:E
@r276
ATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGCACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATT
+
*)?788-B?2HB@*!3>B&>;:?1<'8*>?&/B$C)=:>9*$?&G8<'/G=*>F12<AC&@F!3%026.?:?>;65%&15"2$$0629B-/5@8G%-:>7A$-'A9$*"DH*@)333(;DECEF5:">8+,5.B
@r277
GGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAA
+
++#'#'&)&&((!(#%%$($#%"'(&''((*!(+)%!&%#&$!(+)(!$%'&''&#&"&%&$'#&+&!'(&$!$$&%''("*$(!!%%!#%"!"'"%!"$)+%*(")+$!")*'"'$*$'#"!'#"('"+"##"*""%*
@r278
ANAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGTTCTAA
+
,;%.GF$&4--6)B$/#-//;@H,(FD:7)9?&)!$8B'5/,:%=E++H63#B6"&)A-3D8
@r279
GTCATAAACATCCCTTACACTNGTGTGTNCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATNAGACGATCCAGCGCAGTGTCACTGCGCG
+
5>:H57$A0(&#B-F?B"AD:#F:CA9E,09%?0,%*=/%(##9-6(H0).=>"'A6-C<&E/9"CD'H*':4+"-B8/G;?;04$5G1!C337$'%03D<4-<88*,+;79;5#&0B?ABC;2
@r280
NANCNTGTGTGCATCGNTTTAATTCTTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACNTGACCTACATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTC
+
%%!)&+#(%)%&%$!!%!#&(!%%)*')'*+&""*))''#&+%"'+*%"#'!!&#*+$')+&!!+"+!(!*&"#+!*'*%(&""($!+*&$"#'&#&("!!+"(&$+)%''*)'()+(+(+$(+%*$**#(*&!)&#+''#&*#)+$*(&"$"&(%)"%&*'"*##"(&$*&"+%($&&($$(%%")''
@r281
TGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAA
+
?3F=C*8,(!4?<$:)A6"#+D>B'F/7DE8(85G/8)9C"!H:'$:;4H$)?1&E7#05-
@r282
CCAGGAGAATANCTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAG
+
3<97.:253><*:.4/?5.,$9;3"0+0:@#<G37;>B:?$E+-G:E@G!)=E1!C:5<8D@82H/;H4C6(&%.3B$5>87:6&,4+5=A0@D>EAA/1=!7;=@119(D:1:%1<%(6/?F'9H67)0D<8E9*>',&4=76>A/)+81/'".2:#E+6($43H@
@r283
GAGGNCGGGGCTGACGGCGATGGCNCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTA
+
D*:$+40)*?2'D;3"G3&6C?<E+=+"3%?)D@#H%#F8+?)F9A",AEGH"D-$4=E68?+
@r284
TNCANANTACANTAANNNCGTNCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCA
+
$#*)#)$(!)%!*&)'"'*##"((%(($&%#%&&'+#(!#+++%#')(*"&%)#)"'*&&"$+(+&(&*)#'&*!#')(%&
@r285
GACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATNTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATNTGCA
+
=%BH::0?;$>0=)344=-%+"H,/G3E:'$4GB&/77@E6,514F3+1:4B);:B>=11=2H%$0)2%)A6H=$F1?<+<25=H?'3%31+8#>8((*
@r286
TATCAAGGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATG
+
:'%05,'&05-78=?B5-;&?0!-D"5<<4=DB<#?;,.!&8*A#7B-9#7"*7
@r287
TTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTC
+
*=E%H+-1D(8<'*GH'09(>4F(/-1729-:E&7,3#?4#%:83BB&?>(-8#F<.G"=H3:15=7A"8)&F!'=#0A"$9)"4=/CEGB*=(D+707!<:#(>#=:1+B?HD->83).1C%4:*5%6$1
@r288
GCCTCATCCACACGCAGCAGCGTCTGTTCAGCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCT
+
<)6932F*&9$7*)01%H8(4*/!@24#(#9!%1$&/8H5E40B%6>/F.<!*+</7#3(47"8E95.CHC@>2
@r289
GCCGGACAGTACGTGGAAAACGGCTTCAAAAAGAACTTCCTGCCGGACAACACG
+
"C..B7HE'C@=64;9+H#"./517G8,'F"7DE:C/5A'6=@7B@G3!75@D!
@r290
CATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTNCATGTGGAAAGTC
+
%2A5+8A>D;BD;@E>;!G7<>:%.=&%@%>,"-G1-E>*;BD;!&48<,4
@r291
CATGGTACGTTTACGGTGGGCTATTNTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCNGGCGGNGATACCGGTGTGAGTCATCTGAAAGGGA
+
74FC)E.D$/9!72-A-$<%0/8)1/;0(F6<H:568,+A2@=&/42<*6?+B9::B$,22A>E@/$-#5A1&?6+60:?@DC1C;2:6:?-(C
@r292
GAGTTGATNGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATANTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAG
+
<5@(,H5<7+9C@>@!C8AGE4'";C(D6+1=/(,+?C-8E5F9G#9DB2*/<@A1)9G7.B2>F)A'==G/</('8E4+2F3%.BE8E3@2B>>$*2H7E$:FC--:0$5B-%4H84"0G/@5*.@F';E43&8EH
@r293
AAGTGTNAANACTGCAACTCAATTACTGCAATGCCNTCGTAATTAAGTGAA
+
(#))&"#*+*(#$+#(+"%%"'#&**%&"(&$&#$')+"#&#$*&)'!++&
@r294
GNGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCG
+
*-3C%?!.,%%+%135'%9,)57682%%,#*2?);<0A<4,H=("FC.AF88<>*G81.&0'9<<712D:EH8)%"F)7?+E)H8*@9&@'.($4@17-!40
@r295
AAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAAC
+
<*6-FD=BG3F*G$#.1"3A(+A:;/6;'%=GH(-?4/*92/A).
@r296
GGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGNTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCTA
+
-$C0H1:G;:2=B/;1H68?--4H@5"8$:'B.D/'8((94%C0F.>+@B35>83D;+&A<<"8,@FG6F";)G?>478.='+@*<7'*G@,'0@G";H1=0G48D)A#$='+>$<ED!1D=+76%
@r297
CCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTC
+
%9"G><2/.(03'#=$'&((>'G5$8(=(5@<A4:D!@D--%!
@r298
TCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTNGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGATACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTA
+
<<HD:'(9<=&2525#CBH14,3"@B="<G&HHA'2''&EBGF;*A)D@&%??@>'/4122;!4H.1?'>08'0-#(D;/,19H9;C6+'>179'!"$<1</G#G&E95EG@G$*3'=%*"(@+'GH36<'331')+75)F!26(65AE+-0"3)7(GB@,FD+>#F<A*@,+%-(4206=C,>3A7FE3H<&2B/7G++?)2.C4;-7F2"#?1<<A*F;+:+9H+6$8*D/'!>!6&5;'?@F=,E4E+3;A7DG"(7&;3>"HF6%"C(-F)A!3?*(!7.GA01G"9"&D8=?F#08>)(7>3,16;;&H,60)C.2?52"F9%>3<8E3<8:<.8GG#*F',4:&:(.9;?<<)D
@r299
GCATACAGNTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGG
+
;8C@&4"9!2#<;A<G=8D?8<0&7,83/28'2B++1"H5@-80;
@r300
CTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCNCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAANCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTA
+
,7GH7+<0=H<+H8=>F;80@351&!A0.:B"D:";B5,4C@5317$"+C&&%BH*&"&'7-<$D3BA-)2>9;@3CDA0H-H+DA/A>,-2D$E8D/.357;":!7F;@F4*->:=#2G&$-A+C)6G%70,2.=/H3)=>1<?H:6!C%1@7:8!+D:B=,5A&975E&3-&-.*.,!7&.>5(D5>,:6#?E9<B3)<6#"'95G1@"-$A%E8H$?-6=B6(/-)GD50C48<?.'#@(/<"(GFDH/!1A'BA!5F+F&#50*A2
@r301
CACTTNACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTT
+
&E0+,<'8+%#B$>D"7@?3-AG&F8230;4*?#7B,?#1/+
@r302
TAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATNCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGNAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCAC
+
A$*E>=.DA8/")9>:.4+(1(+C?)C.10=")DG-)@@4!9':;C*!ACG71/54>10'?)C.B'D$@<?2.BF430=<F/"G"C)'BAF9,843?=B)>/(#$6!8+;!G';AA1&C-E<A#,%72:)C)+B1*A+.*E=/!1FA(@D16C5)*@A(:(89B'@3#<&1
@r303
CAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCA
+
3@+(@C!),4>*;3D($/><7620)190,(42+<0>0HCE=G570<5C01<=!DG0#0-5E=F'D;9(8E?CA8);.C?(#6*E!F.<'@3=?1</7/;G%&HH"&)0$;1)2C:&H?91@6C&0136C3G0=;+<#@@F2$3-8&#<&F#5!H;91>-,%ABCD!5@
@r304
CTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTT
+
0*C%$64+A59?>@GE+;>>==E7&B2H-0!82).CDD%FB+4(*/AEC.2H-=#H+E4G8>+$6)A;B
@r305
TAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTA
+
D9B:(EH49FC$3/)0H5&2;+D&$1(0C21CG27E5;$22'<B-326<#8#0?%!&$)
@r306
CGNCACNANNNTNGTNANNNCANNNNTNNTCCANTANCATCTANTNNNNNTTGNTNAGNACAACNACNCNNCC
+
"$!$!"$"!#$##$#!!!!!$#"!!$##$!!"#"$$"#$$"#!"$!#!#"#$""!$!$!""$##!"!!#""#$
@r307
GATNTCACTCAGNTNAAGCGNCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAG
+
$*%#**(&('$("&$!#*'&'&'+"&#&!*&*%"%"'&"*%$+#*!')&#$%&+!'$(+'#"#'&&((#'((!
@r308
TCCNGNGGGTGATCGGAGTAATCAGNAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGGTTTCTGACNNCCGTTATCAGTTCCCTCCGACCACNCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCNAAGCGTTTGATAAGCGAACCAA
+
*"!&(!')+!&&!#$)+*!'#)#*%'!'%"%)+!"(++!('"*!!!*&)%+)$'%*("'+"++&%)!(++"!$!!()(!$)%%)%!&+'$'"(#)&+$$&+%$#())#'$)#%"!!$#*)$#!!%*%$")+*'%(*)$*&')+$%&%#*"&%%'+*)'#*#&#!***$$'(+'"+##+)"(('(%%$'"#%*#&!+!%!*
@r309
AGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACG
+
>EA#BF.GG3=5+&D.H?F2&D>B034$H2%DF"#*43.;/'4E%23,03G$)E'</!9*&F03&7D@5%=/+$"*'8,*-/*"#=0
@r310
TCAGGTGAAAAATGTCCATTTTGTGGTGATATATGACAGACAAAAAATAT
+
EA:7C0&-#.<G8*D))A>C/6%%:4@!*94=+8'3+>)%+&F+$9C9+$
@r311
ATTCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCAC
+
2HE7D169<%2->9E7=-+4)<??345B>1?H1-.CG:6*.$A7<G7!5CG+%7%,A;1/**G&+G:'G
@r312
ATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGGAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGNTGCTGCATTGACGTTGAGCGAAAA
+
+F.(9;HBAEE!/!7EB0&D7E)).-25/.A-$C+-:0D%2@H5*7;%()0,73:93%DB0!$+#/($$4"*)13;/6>780:?F;GCAE%F31(>D;#B,;)G=;?D%>=9:-A+?FD7:=F0'6)<B(26'+23,F0-'BA;<B##=E30D2B$.G
@r313
CGTATGTCATTACCTATGAAAGGTGAGGACGCTATGCCTGTACCAAA
+
'"=8F8+8%')B/8>;B5<A##0&*6B;.)/H"F0C=.:*H*C=&;,
@r314
AATTAATAGGCATCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAA
+
'3>@(87G867>:G@:$2-<@A#E8E-.0*F.$:)@;G1-2<C5;(G-C,
@r315
NCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGA
+
#&+)"$&)'##"#"&'"$"()$$*%)"+")#)++&&)*+(!*)"!%#*&!##"!))%%#"+++!(#")+%!%$*($"&&+*(*&()"!'
@r316
GTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAA
+
<>AD7;22.>-'BF<+*&1"B9"::&AB%3$=>8F1)&23CG?<!?:2@C$>%;A-3+>'A&+;":2"(,"*$
@r317
GTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAA
+
H8,+07A;)F$-821/$""=@&:>44D2A#5::!E+2/5.H2HG6H<++6:-)&2"G>D"!!88<#2&26=4@G<#*!G7.$3<>:8"0<);.-0HB$E+4H1#;+;7$6!461
@r318
GAGAGTATCCGTGAGAACGACGACGNCACGTATGCCATCACCGCCGTGCAG
+
($5#6&4F&4#@%5;&;8)-8##>"$>A2D&B1>,'=!>E;(D#=%E-428
@r319
TCTCTCCGAAAAGTCAGGACGCTGTGGCCTTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTC
+
E/AH?%2$F=7/$%)#>(#9<3:=H-C=*?-6!71?.?29&BB%B(0!:A:4&0#4(084<$(61'E1#?6;H)+?!F&>.H@5,&E<<4-.D?$4>F$A1B,)#H+2%(1>;F%&3=A3*
@r320
TTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTTCAAGCTCGTATTCGTCAAAGGGATAATCGGCGTGGCAG
+
C)52BH>8@+/C1237(A!F(/06$>GF3AB)5%='+'48&--/.<06+46@$-EF.>$AH+#@.HD6?1C&=$:E=0(&41&6#1C2490#G%"7@
@r321
GTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTT
+
@E'CH46&1-)!9=9<(""09);3/,B+-=114*#5C%CG$HA2=40$+!C3
@r322
NTTTNGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCNATTGGATGGAATTGTTTATCATAAAAAGTTAATGTTTGAATGTGA
+
(A%3BH@"-!?0G?2B37!;($>1/>4C,=?20HD3#B'1#+6A2(7@/E%8)B1-9#=?A9,#,B"11'D)G,$)H);6E8!,/C3*>,D$EE>,>3?(82&#G52.)D:9!F/#B-E*8"
@r323
NAANGNNGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGG
+
#'##*&&+))$"#("'+$+'!+(&'*##'"$&(%'$)#+('
@r324
CGGTAAGCCNGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACG
+
.80/3,H!D!B-?@':B"B%(/;.('F=@'7"#,"("(766A.)(-GD$6GCG5G0)+8*@E0C7%:D)B<B?41AC6+GF'34G?*#B:+;)+E+#)BD9%7#$6B&H$)DH4?256!.'4&GDC,2BE!
@r325
GGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTNGGCAGCCAGCAGGTG
+
<9*D0/!(=.?2?)06<69?@$@/'G<2!9!.-.=H/<9*B39*$?&)'3!*?7E3$+&/2)DF6&:4<>:$4G;!#H%>G,(A;898?EG:F=E%.:)@D,D1E;-%4>.:'&*1&+"6%!AG++=></'95*F>3;,
@r326
GTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCANCCTCACGATAATATCCGGGTAGGGGCAA
+
A54;!.2:$#&E7-G;$2G9H/+,&@BC"<EE,D*9-69:75>8E4D%:)H&!2G1AA,:0GA&8#6.3,5+&32F&<&/7=.H+?52>#C16?@!2G;%
@r327
CCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCACATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAANGTTTTACCAATGGCTCAGGTTGCCATTTT
+
)858;3F2C$0D,*'!":>CC-A6EG#@+2(,F!H3C7@,/'?+<)2#9CEC%?!7%!=?;5$?2?.@:!F@)01'">(F,2+9(FE0A*5,H8=38,6B.)C4()%C;0763!8%-!%"-A93C6#%?D;/&A'>/B#'B$<<!@!H.?B7.@):%@8*.70E9.#>4H$,
@r328
NATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTC
+
%96&6#-570D9FE@@@'(((H(-(@*DCGD(B?@%C8==8<8#D2,4)1(#'H)
@r329
TCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGG
+
8G?*F+4*-@$#:7"-'80,H2#4+DC&CE<'?5;$3;+*,#.)AH+"DH2,)<736+:;D=H=.&AD43G0!=!3)CC=!$,:@9
@r330
CCCCGCATCTCATGCCGTTAACGATNTGCTGAACACACCAGTGTAAG
+
+4'G%"4.8>*>/H$68&9G=C>G235"G9H*9*B#C.!861CEF*@
@r331
AATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGG
+
=D2+"B/="-'A=7E49=:C2)4/?9D488(&/#C8@&$>-'3'D%1+9>$4,A;.&*!A3-$;B/),,0B%%?1!'%39A#;C1'@D<0C+:6&53@,8E*=7/?>!GB15%8,*")3=%*
@r332
GTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCNGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTT
+
@>7;#-:G#+8FC,@$A3!@47#5+05$>(/8E/74)/*#$C=,>!*G>-#19#5G'?"?-=&%;.)-=0?!<;F:"F;.F$$AB'4!CE!HF3>0:C#()G2H3%!&"@E(!8*G+B=*9#6D<1.C%G/;-#FHHA=-604=>9*4/<-8'80%2B+G4D7$@#<$36B5.B<&*">BC.
@r333
NAATCATTCCATTCAAAATTGTTGTTTTACCACACCCAGTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAA
+
"84>+C8EG;!15F%.<73E+%D*?%8"E?@'(#H*#&'(9,(5271E#54/!#FFA,69<@B**7:FF?7H@(.C&A=(84+H$52GDF9&E+/B6@BG<9-?."?F8)#(1C437!?4!'6FD%6?DE0;2/.>6,!112!-4C."B&,;$+
@r334
AAANGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTCGACGAAATCGAATCAAACCATAACCGCNATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAACTGCACGCCATCGTCAACGACGTTCTCATGGGTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCA
+
<B67.:8623/<**2-,G"D-2.-"0'9.%-+/,:"'#5,4;4=410F/=E%AB'"F=3GD>(+*5$42#4#E2.9"8%6:#6#'%5G/?3B!*!!6BB7:8D>CGB1@&+6+D-&+=&>7*%=9+F;*,4A.A1H>?!";5,5:*F:8@;GA)*6@D:">?3,F-D**&48$<-CC179&+C.@?$$('(5&C4-"91@H?*,,@":("6E0.#,?!,!0'B#E;23+:C37DF-HG9*</;?D2<23+?$E9.;B'.*/-C5)@2HB30*E/C.02>4B."#*B'B/<=/E.?)A?"''#F,B!9&@,:G/G0G41,:5C,=1"2-<4A>674=C=<)DEB3,94C"!?<<=D5=.F73G63?;#=E68&3<E77&GG?&$>8'5;'CH
@r335
NCATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGC
+
!7..:)(,@F77A:*0G"<G,?;/>-=.#C7*+<;'2)<-"68?41;5''.D+B31*
@r336
NAAATTGGTTTTGTATTTGGGGAGCAATGGNGATGACGCATCCNCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTAT
+
+$$+''(&$'$"'!*"()'+#+%(#+'")%*(*(++%'*'(%$#%)!)*#(!&&"&++*+!()'!#'+())*!*&$(*"!&%&+&$*($(")!++!!")'*")$#))!
@r337
NCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTNTTTCCGT
+
3:(2:3(H'6<-&C%$'$B17H71$@G&3(E40C,@.*61AB*%//6"..
@r338
GTTCAGTTCTTCCNGGCNGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTGCGGTATCGCTCTGCTGCTGNGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGG
+
(3'93,?4**.)+8='>E1/3H<E4)6FC3AB24&0"2##&B$<D2#+D5,G@@;FH0HF!@",!0.,D=-&D472;6F.124=-*.4=)C6-!:7#%5$169.;HC*@')-$H:."!.BH9"!2=,)-C4FB#;B>F=?:)-H6;4'3>+4B($18/GHA*/-?1!55A0;;,,8+%$-/$
@r339
GGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGG
+
B&'A3)1(G7")>-B-%E<)B?#0#4BH1@8(;DH>D"8$-C*7):"#D:>=H2-!<DE$;/0@E";<#')C6!9>>
@r340
CATGACATACCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGNGATGAACGCNGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGA
+
F4")<(>0+5.!-=(4#(+)*A+.C3@?C7G%)9/.<>4+H4;)+=H53!?%C9$@D79A@.BB+@9/0*'%!<*@4"3">3@@#6@/4*&>.F1=<+.75;)B+E6/G%$F-@19C-50DG(H7D*,9*A+B6-C!1"%:AB.9E2;"G?!"*4#1H9%#A5H?::D;B4$3@$.5%7*1"2'#;#"@/1
@r341
TCTTNTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCANTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGC
+
!8F/(;1':7>:-">5;D5'193G#3;E*:HH7B&8>4FC7&D+53F&"B%-"49,71#4"/4=+:&=60H'="D.A"E.(#;B;<8D@2=(+;<76#9;!&6G39&!#D(6*
@r342
NNNATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACGCGTCGCGAACCGATTTCATCCGGAACAGTATCAAGGTATTTTATGCGCGCACGAAAATCTTCAGGTCTTTCCTTCGAAGGGGATCCGCCNACCTT
+
#""+!&'#&)#!%'+&$*$(*'%*"*#$"#+!!#%'+$)$)&%*')*#")+)'!"%&%(+#'%*#!&$%))$)"(%#($+!)#)**$'(')++)+&)'((#%+#"+(%#*#*&##"+(*!$&#"''(*&)&&"(%+*+#''*+%'+%"+#(#&"+&$++'%#)*$*+%(%'%!#&')(
@r343
ANCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGT
+
)%+'*++'()&$))&$(&#++*()'))*%""#&)$)!$!&"!*$($!$'"+%(#)%$++!()#)'*)")#++'!"%"%!&&"+
@r344
NNAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCG
+
&&+"A,HD/?F2G'C*CG+1#3):1E5:5#E'$'-C3)+4,HCG:&@=#D<4*$*8C5D<$
@r345
TTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATNATCATCGCTTATAAAACGGTTCGACCTTCTAATCCTATCTGACCATTCTAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGT
+
.*#7-//?&F=2:@-&3($3#@F)2*'3@&2A/A#->?585#+,D3A/%5%&7GECG5E6:3&-:(5(7"?1"=(,<+09-F-5%.6=+&BB74E5=*=H/9:6!#0?9$",:%-!-B=9+0&*19-EAF*-8H4!'"85!GE$>/)7E:#>H5"+$,HD,$'1,&*FBC$0
@r346
GGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTC
+
,=D1*"+<3A"9<E9:);!6>><!HCF.;%9@=A5A<38'C!.D=?)%2,#.9A0B3A*?-$!"&9E3G
@r347
TCTCTNGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCC
+
7643$5A*3**4<)3B+G6DE<82HB5B3AB@-4"8*.5F3"C0&>="-A@!"2;>B
@r348
GAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGT
+
$841@!.)**5.*>&>>)6!*HD(')7.936/!%E&3G((=D0$:*
@r349
ACGNANTCNNGATTNGNANACGNNNANCGCCCNGNNNCANNAGNNTTCNNCNAGCNNNNNNNCNNTCCNCTNCNNACNTGNTNNCACGTAANATNNTNNNNNNCNCAATGGNNCNTAGNNNNCGTACANNNATGCCNAANCATTNNNGTAANNC
+
$$$##!!$!!$$$$"$"$!$#$#"!"##$"$#$""!""$!$$$"###!#$""$""!!$!!"!#$#!#"!###$$!!$#!$$#"#"$"!##!$#!$!$"$!$"#$$"!$""!$###$#!$!#"!$"###!""$$"!$!$""$#$"#"!"!!#"""
@r350
CAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGG
+
H5=E>E0*(CH)'5%7<3,<?9!8--%4*+9+HG8D-$73$:*+/:<8=5>.%H+?5%!&4AG)=11<59!3C1?3EH!!@;-(2329!2)!9-:6?)E5%+,?."@0!/D?)
@r351
CTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGCGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGC
+
!4@BC!!+#./3($H;@B2"=9B&!@>?(=61C,H),9'725,HD>,"$0'!1-+@8<HGE#HH&7)A!;5-!0!<;,"/@FH:>"-&)6/BG;?#-0?,9.")2;E+F-5995%>:.212/5<C)9&%;#CE!<=',+')+C>-6+;!&AE
@r352
NNATCGNCTNCGTCGTTCNGGTAANGGNNNTNATAGGGNNGGGTNTCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCTTG
+
$!')($*'!%#$(%%)*$#*)'%!$('&"#'%')$!("!#%*$%"++"%!%%"&#"'$%(&+$$#''&+%#)%)%(!%#!"))))($+*%*(("+(!$$(&'$$'!**$"#"*#&'#'!&$#''%*!''&$))'))%)+#+)'
@r353
TGCCNTCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTNATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAA
+
"+=&0#1,B;!8)@*G5&>*GE!.7E:.C08D.!?G!24E'2%'#=,**&*D',9B2$50=2:8.3?9%3%F:36<))C*>F1<A2.9D6.@C"&&?$);DB>=)1(#75$9*<-750A6&E*21#G3"@
@r354
CACGNCNCAGAGAAANNNCTTNAGCGNACNTGGTTTGGAGTNGTNNAACACNGT
+
'%)"#%%&&**$%**"##%!$&$&'*(&)!!*"($$!)"!$"&'&#&*&&""%!
@r355
CCNGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCA
+
#((+!))'$&)""(!+*!&'$%#&$'"#*"'')%+'#')+))#*'!%*!!%'+(*$()!'$++++#"
@r356
CGTCGTAGTCGNNGCACCCTNCNNCAGCCANCGNAAANTGGCCAGTNGCATGT
+
)'%&&)$#'*#!#'*!'"&$!#%&)'#)#()%$$"$(!%*('#$))%+*)(("
@r357
CTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATNGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTT
+
D7/B":#C%&F('-&;'!8+;1C&,1)6%##6)4D8!FG:B"D@@2!9:+D+:9A"?/<"&:,'6@!>:$4'%,,E-81G<<";$DE+,&<"G-C+#A>-H=(<2:D0-,0D";D81D?=9;E.@E'!A<E!>-4395!-,9)254-:
@r358
TTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCG
+
10,(,<8&+<AF57?;7<*-&#/&*.81(G?+=**C1C1.2E8D=4/
@r359
CGTTTACGATGATGATTCGGGAAGGTGTGGCCATGCACGCCT
+
?9C)";CG07EGF9:FB)4;5'3/@%ED9*!((B&@$:5).)
@r360
AGACGTGGGAGGCGAAAATTGGCGAACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGAT
+
:)=!A)0$G,ABA8-08*+$8=5==77/.!93HA2G8+9/'&C<@."'(+$<40:F'-2>:4%*,3$B4(/++F<;58'3CDCE)H$$;G1&F?"D/*2D<C'@D'@60)2.H-24=-G*D#.,,6F.5C&19'B@G;'@%,?!
@r361
CGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAANGAC
+
1;$(7<;,%AA>*C.78'@!-80)34>6=/+D9H(/=>83/(/*#='#=?A)C-E?.=*!)65:"7C508(<4'9D7!48E=#G-%>B#1;9D8G:=/788%+0
@r362
CGANTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTNCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAG
+
&%(0::"-B#?:9@+6!D@<9!HBGA<-;/A-&%(3.1D785>,&"A-)0+8A<+GG-;1D"0H?4'28C%8,;G)'+$8AE+E31D&0F@(H3/DA)?(($4=A
@r363
TTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGATCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCNGTCTGACTCCGNCTGTTCTGCCTGCNGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTG
+
D;'DD:<@01D%56G),9F5'.,/B2<%#85C'.*=&0;,>8)@7D2:&=0<#=2!A%C0.8;)B;3;/7B$@G*+F0>341C;>:/'38=3?2%8"*EDF)/@4DF;9;)8)'C.11(;B=HE.5D26/0/7'E3.,/&)4<5:"8H!CD>$AB30$#+.*(36E4B&<#:
@r364
TGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGANGGCCTCCACGCNCGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGNATCAGCTAACTTCTTCGTGTATTTTGCATCGAGC
+
"0.68/!',38=G."1.C.>-1B*3-7++6.C$H<G+8%B98%+/A>98%22$6$D0;9>*-5;CB;F34F+@D&:*3'03)9*0CCH$1-9;)0!;H="41"?<+H@=DB75$(:?#(#+$C)/A,&!(C7)B*G1E-'9"'%*-=&"9?##39+16@2%(!0;7,'0CE35%G/-,!!6:+G?0EFD(1'<2?+*'/:#HG9#,4A7=9B#::D75C'&6#0.EE*-+A)F!(',F1@/:7,6B%-%/$H">?3+$+5)EE@2+7F'>17#C2>01&>A+-#!?#F,0/)D"H?"0A)$$5-?F@C83/5>8%$"2=D4.3=C?,B$?5%75*>E2C,6;''<>.@.@*5$6.H@B27#?!5E1<+3E5+9E0?<:
@r365
AATGGACNTNNACCAGACCGAGCCTTCAATACGCTTGTTACCCAGGAACGTCGGAGAGCCT
+
'%&)(%&#%#$%(+!+%)+$$***#)(##'!&()$*'&*&+&*++*)+&(&+#"!'"(#()
@r366
NAGTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTNACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGC
+
"#)#@;0F=,=:=A:%5C@4+3/+79C(E%7#.E*8!A":+G?6+*<&F6,)2C*(B(1&-&#8>:H&F*E66<236!(.1'"62EHGBB(?4)9H?BB%*0-<84?/8;0$,)G&A28AD#&?7A74C312&G/)#G8H3*A&!!1(0D115618C'!0G&"=%A+*5A2-2>FF2"A@8"6F,;2:/>A&@EE-0%<@C(+&D%-6A5:%<$;2217F&4";7
@r367
CGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCG
+
A&/(16?@G,+%4,$1#;#F74:$F)+0)5,EF*7%"%0)(:3;"'8@)?)(@1B+)(#F/?<+H9$.1>(%G4.,%&;#$>E!9"6?/;
@r368
CCAATGATCCCATGCAATGAGAGTTCTTCCGTTGTGGGGAAAGTTATCGCTA
+
?E"(+H,F>5*&7F;H=5B@)(,5.=-0G,511,H5'A,0!1++3/$F3*$F
@r369
TTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGAACTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAAAGGCAGGCGGTACGCCCCGTCCAAGCCAGANATGACAACTTCCGCCATCATCCGGCGAAACCCGAT
+
5"A-19;&6-)%/5#5-CGD"F@!@C10+?=;='H*!$=H-<A18E%):=-66*/#*%.,<$B5BG?$D2.=2"<(9)'0=&8333E6!)5>$-329F8$8!4"$2,D%8B@9/E;G/-G1">""7:"":5CE=C?,&:4;6,G8B')B
@r370
TNNCNNGNNTGANTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGT
+
*&!)!#&!*#(*#+%)!$$((!$*(&!#!!&#)$!#)")*'(+(+&(*('"'%%*'("%'!('**&!((!
@r371
GGGTTCAGGATGNAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGANCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTG
+
%+%%$#%!)*+%("#$#("&&'(#))((%((("#"+#%!$(#**""&$*!*$%*%')"$!(&!*!(&+'*)*&)!%)#")$+&#!(#%!'&""&%#*%*$(!&#")*#("$%*%!!"&&'$++!(#'*''"$("+#+'%$("!&#))
@r372
TNCNNGNNTGACTAACTTTTTTATACCAATGTTTAACATACT
+
*"'%!'$"+%)*+#!(*$(!()"+'*('#$(%((('+)+)+"
@r373
ATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGNTGCCCGTTATATCTG
+
<(22(;:D=8*F@+45)H.#".:G7;<,D?-FGH4)-B,)0%8A:+G+<08#684E*9F#8850<3272$
@r374
ACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACC
+
70,(:(E%<-/=.4C%'+A"/5#*F;')>'=B%B-<3?=F6-:9#CB/3CE#H)C=$?D?1B<8=?22-16:
@r375
GTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACC
+
,8:">2?7&DD38;0!;(#H%+E:79',@$1+>*F?1*(#D//
@r376
TTCTCCGTTNNCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACAGCCGGTCAGGACACCCCTCTCAGCCGGGAAA
+
#*&(%(*!#%+(#!+#"&&'$)%"($'!#$"$)+'!!)$"$$+%)&!)!))+)#)$+)%%&!"+)')(**)+!%)"'((#!#"%$#*&#&""")*)*&+!'(%&$)+%&)#''#!"'$#%)#'#*&#$!!$$$+($!$(%*$!'&(#
@r377
AATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTNTCCGGGCNTCCACGCCAGCGT
+
&#(+*%!#((&)%+*'+$$%**'%($$#$&$(*&$"'*$#''%')'$'!"')"*(%#)&!)&%&!$$%)))"$+""#&%%!%#%
@r378
GTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCG
+
.G8<9$";8=1/5;6@;.C.1(FC=*>#A%,$4C3B.#C))8&3A/&/8CB1-&23(%'A%/G%DF1#>;7A<1(#;,;)@,>@'B#D2.4+!C'661.)/H@?-D/<2":3;6!F
@r379
TTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGTAGACCTTTTCCATGAATTGGTAACACCCTCGATTGTGCTGGAACTGCTGGATGACCGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAA
+
9D!'#/8>0FDB=#$4B891H,%7&-0<5(5A$ED)';$(%)+7*9A3D$<+&:@"3+-!E%@/44/CH8>&D530H?2/H2+F*<41&<39:7;$##34!8493GA*"-'A69#$17G-%&78*.'=>&G!9!07,:=06%9,6):)>;D"!(&A<%.%'@:3BB)<CB<EG;1970"G:&99;2E")"-%;D1;5&D-8/%300>,?81B)886@8G,";C++F78F>A9+0,AG7G8%1>='<9@$:;8@%F;80+>#:,"&'$0/8+BAF;G62714C2G$2B';A8/%,4@0+F*;H0D!-5(*HF5!FC;A9+*<2F;C#A</F4/!F.'3B.5
@r380
ATTGGTGNCCTTGTTCAGAGGCGCTGAGAGANGGCCTTTTTCTGATNGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCC
+
#()''$)$+&'(&*(!%+*+$)&%$$&"*+$")"+))#)"**'''&$'&#!+&%+!*)+(%*(!&(!*+)%")"%'(%$*%'%)+&#)
@r381
GTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTNTTGTTTTCG
+
>9=8::H6++&((F38/C91'A974E#+,9#!6D1A)!<A4D:'EH1'@:$3:H;?;1+1$B%)H%2A%15'C$:,0);@AH5B(/<@:%)B#5C)H/7.A*?>A"5,(1E!9-=185%$CB3=C:);
@r382
TTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCTTGCGATTACCAGCAGGCCTGTT
+
15C@'>63E(-FF-/."/:'2DA:G$#7";59-D+BE5-+0A3H+&-8-5F02HC4/+A
@r383
TANNCNCNNNNCGNGCTGNANCCCTTNNNTTNNCGNACAANCACNGNTNTNCCT
+
#!#"$"$!##!###$$#"$#$#"#"#$#"$#"!##!$$#"$$!"!$!!"#"$#"
@r384
CTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTT
+
$G2C$)$<(B@&0B5@8AH7;H4>6C'$,,"4<<:H9,;A34@<>7)5/!E
@r385
CAACTCGTTNCCCGGNAACAANAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAANTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTNATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTNTGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAG
+
&;%302=5'C3-)D!A=<,G8++@>6<#0$H3B9B#E83:-05638+F',7B7?36-'2H9;@-84<9<,04/%D49F9:21#HH>B4;E>)3?'7!F6/1<C%77-$;(0&"!'?50B,C,B5@$4&")6(4G9?/9.?8!6A>A("EG3/),G?C82@E5*+&(EB.F9@=<)/-#///H'8)0:8)G)==B>.!;+$-((!,AG7FH"",B./,<!>21:(<8E"34C";=)+8.9'5().7,HH:@"!08)$E03C743($)9E./C#C8,=),A6#>;'!?':EB,&E;$C.:H&#)=AC6%*3@
@r386
GGTAGTCATAGCCGCTGGCCACCANACTGGTGATCAAATCTGACAGTGCCGGGATATCG
+
0=D?)*2F*!2@7#6!,;BE=2%#7*!>'(?EC4!*'#A6?;3"CE;#06"'<2&!DE"
@r387
CAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATG
+
.$4/+%5B'?$50<7-.!H6*7!>.7*7*;(7;F*;C=3=9,B($4(BA-1/)/-!/B'%50#3>36GH!'(5$>0D'=FADB+D/;,/9B8::
@r388
ACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAAC
+
H+1!EE1%"-!G-H!"EF%"C%:H5?A'C3:(;387D'+=)"&9;.9)E&,<(&-HC+H.*).55.-3/@=,#"96)==7"3.9+#:'1GC41$@H7"/)#
@r389
ACATGTCCGCGCCTTTGATTTCTTTCACGATCNCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCCGATTA
+
DD7<=9.E,:4;;%D"8+#G9(,E!=<!#@@C8!'&B'%>G&3HA,#0/%:=:,2H-6.1=;.-A-H*4",&
@r390
ACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACC
+
H%8=,FH9!%&)F-0D//5@BDE:GG/&>2!#>#D&H,F1/$<
@r391
ACCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGCACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAANTGCGGCGTGATTCGGCACTG
+
-,'69%'-C182C='7"+DAC39B9C#&)B*G9A%?=,+!G?;C!#30(/H8F@9F)71)73B:1,#)'=1.#;%?2B=#72+4:*G%)7)%*@:"6/=!10;$D:9*/3<6@?,77@1))30/F.)$?+)A(<0C8;$/$,-$C15D?#3EB)3(%)
@r392
NNNTNCACGGNNTGTNCCATGGNAATCTCTGCATCTTGCCCACG
+
#$$#!*)*)&*$&&%$#+""&!+&%$)%%%%'&"&!&(%%"+"+
@r393
CCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGAC
+
=H"&*%>2@!?F,!?)5B.H?"8"&$.:A'!:1;2?@G!'.?73$E0$=E?@5@8<9E%CD(/-(-#?A4#1(&9=F$5&;8F&-0(3BF@,%)F,"..))D>%<CA<D&FD1$A*@")C#*!=
@r394
ACCATTTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCNGGAATATACCCGCCTCTTTCAATAAC
+
5?!@;#F+B(/@$;&@F%?<EE<2H,'0@99*(4A?$'36G=15"D.5$7A;FA%)1,/.GB7:?2
@r395
CTGTATNCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTNTCCGTTTT
+
@F)824GDC,??G%&7AG:*;$784B>*%3E:+0D+957G02(CH1-A5>F:1?==3"2<H+1)B1&%8:.E!?7F
@r396
AATCGACCAGTAACAGGNGGCCTTTTGAAGAGGATNAGAAATGGGAAGAAGGCGAAGTCATGAGCGCNGGGATTTACCCCCTAACCTTCATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCG
+
,-%G'F;0>-(.7-G#4BB>4B60$0&FC)"?#!/'7$":;&7/=@"10F#&*5B'&D0G78!F'(C/F01**)7.B>4@&:H&?7&8)+G,'0D5%,0FA-A$6%9457:;6F#/3<>17F27=3.=A11G.;CFHA:BE9,%./,"6-5-30B,8'0@<H6GH<2D%=
@r397
CTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTT
+
),@B%',1,G#FC.E/8&-./=?&*2'CAC!A;@E.$;&8!?#+:<>/$D*'-=&1BG.#&24)6C)!(44(34')A@1?.-=EH303H25@2D(?32-(+$10='E/)5!7!&'@"F<A!@!</BD.(8(8=/95*:8#D:)38?(16#,
@r398
TGATNAGCGAACCAATCGNGTCAGTACCNATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCNAAGTCGAGAAGGGCACGAATGAACCAGNCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTA
+
)+5C"8;!<..-,232>25?+853">/&D$6C8("BFF&%=A"%+F@2;F,$CH,%B1G!49G::,F%,C824FHBGF*#2:G<,616;+<>(#=,3;B?&B3/5CD+C4,6!H<6>&$6?/*0$A";/%8E#7,**.!F(2!A3$"H"-<D3A(,+1(:H:-&70#,87B9B=C8;%$'2=(0
@r399
CCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGAGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGC
+
->,((//(;?A!18"<<0H1";>AH,89)/F;HG?3"?+!)*=)<96#.'%5GF7C,,+D7'*315%/#*59C*;#7,G<6B796@9<.@@&DDH%''G+17:;#=!)05*C05*BG9E1=>&D@&@1>-H:+2C9C((AG7&@75==D4*B8=9G?5$515&H>1<G->0F+
@r400
GGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAATGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGAT
+
/%;-)%80=;2!!"1G"79#5E2@B3?E9E-;H?A#G!"3,&+$A?4B;@08E5!*H1*7$=4B9<294;$&=,&C/8;,38<23?07&'0
@r401
ACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAANCTGACTGATTGACCG
+
(E4'E!;9(9!79<1+*;-,#">%2/;(7@2//4G3!:7B7HE)0"-BH2"@(="
@r402
CCGCATCATCANTGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATCAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAA
+
A-%2?FHE)C'**'0152H!AED,D=A*D*6&+7%(7DH<'-4G#E?97*';D9&'B17&.&"0A#H-3?39E643?;:)?".=,D'(DB'**
@r403
AAAGCGGCTACAATACGTGCAAAAAATTCGGCANACCGTGCAGAAGATATAGC
+
#&)&%%(#!$#*+#)%(%+**!%+*!!+!'#("+*#"%"+")#!"##()%#!+
@r404
TCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGNTCGCGGCGGCGTGTTTGTGCATCCATCTGNATTCTCCTGTCAGTTAGCTTNGGTGNTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCT
+
69D51;F$'$#*F=0H</H7405>&'=6!4!0:GG4,>@G#E=7C<;)%G'/F<F3%'08&3&'</;D(9B<+D%,3,G6%/!4"H;'?2'!(6?2,(,,61B4,%??%7!"+@8!3>$"E,;B@'%0=&4?H3C?D%CGD%%5(.!E+B8<@/%?-<B5@@H58'2EH.$</DF$F#!%:?9?#&H=!$,B<*1"?:.9;<6:B$AF1$;$=FGD/033@!06-E8::=GB>),;,4A(:,B-G8<@76#B.<;H3$@>H!*#.%#(!C4E$"C12E>B1$6%5A$*<#7(4'E0%A37F?-2!2
@r405
GCNNCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGNATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGG
+
)("%4)C%>77HE5:7;'%=BH-?C<?6.--7=B7.7E+:';!F25:8/);"%!G$>GH&C=43?G530"*..65F0>0#GD;'A4&2F=((E576+?(<.@7'2%<>(:@
@r406
AGCGACCATGCCATTTAACCTGACGAGAGACNTCACCTAAGCAGGCCCATAGCT
+
B8#+=)D)3&=.;08(,E(#"$D6,7D)+,4=<&A')(+5:/BF8?2(D?9;,3
@r407
CCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCC
+
C4%AA*84A@(B)=F4B%&84%,/657::9($'1<$))F()'
@r408
AGTGGCGTANAGTCATAGATGGTCGGTGGGAGGTGNTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTC
+
+)(%&"*%'$))%''*)**((*+#!+(&!#'+'&##*$#+%!%!$&'&#&)$)''+!!%'*!++#)+))&!')!#%'*+#"*%'*$&''('+(+"++%%'('$#"('%$*'#")$+*%(*"+'*&*$+("&"&&*'
@r409
GNCTCAGCATGGAGGACANGGACAAACTGAGCCAGTNTCTGGTTGCCGCCAATCGTATCG
+
)&"+)%+%"$'(!($%!($)'+&()'!%+#+%"(*+$%%!(""!!++%*!'(%+''+')"
@r410
GCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAA
+
G?(859+11%HG"?.9:.?CC.9E(2@>$23EG=++0$E5G3$*F:F*#<+,9##)AD'+AD$9*@!!)G;(#(:B-7,-7)5/>+/7(,9#4C!BE+1>1@H=:3*C/")6B1(D)E.
@r411
NCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTC
+
#+(%)!+%""")%'*("$*&"+$*%"+'+#$)"$"()&'#++'$##)"++''!"%*(&(&$(*)(!($&"$")&#
@r412
TTNNCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATG
+
'&&!+&!$("(+!!)'#(+)*+)$*()"#&#++&++"'(#)
@r413
TCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCANGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCNGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGAT
+
D(=(<,7C?<H+/""D:8D/4+2-&F4=;/'5F(E7+6/3.7@)CH!>85,"+@4>EBG.$E=4E/.(*B519</'3<$GB;/(?>!;9;-32B6='6D$G=':$2'!-4=7%710&#16><:9<"5F>>881#":02%CD4/%7F9F)F281
@r414
AACCTGCCCCTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCAGCCACCGGAGAAACNAACNAC
+
+#&)#$'+"%+#"##)$!%"##%+$'#)(%+)!+)+!$#$(!"&!%)&!!+#'#""&'!"$'$$&*)+)#)($
@r415
GAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAANTATCATCTGCGCGGGCGT
+
G0?.'49>=2GE01&<'H;3C"2)+G7:''-+-4)G<9"31D&,>A++,03
@r416
NACNCACCTGATGCCGGGTGTCTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTNGAGCAGTNACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGG
+
!!)+!$$+*!#)(*!"&%")"")'%((+#"'("(+("(%"&'"#'$$($%"'+#&!*)!)'&"*&"++"&%$*"**)!#'''*$*%)&!*&#*%")*$#++(+'"!)&%*)""!%)))%()!*+#'"!('&%#+(*
@r417
ATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTNGTTTTTATCTCNGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGT
+
@+-5F1F&+B1"F/,3295F!@2%**1-8(-H6F#B+14<,,9475;H0*8-:<B%531D()44C!16H2=43*:/%G08+4GD.47GC"+F+:<37D/6H:(/#--H8=#E-GHBH0%<+(@+(
@r418
CAGANGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGNCA
+
D?1E@/9:E?&>)'A"?-(:A/;--594!B0'>B#$=':D:
@r419
AGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGGTGGAAGCGTGTATGTGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCANCCCTGAAAATCAAATTAAACCACACCTATGGTGNATGCATTTATTTGCATTCATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAA
+
0F3#2#2D0!4+3;6E:8C%E(@14.<1%!0;('+B9.$.<@1G(*(%?7C<8H(@#2$4'<=/F88)>%C%:8#8FA;*7/25'AE'D9.(-6(3138B#?'+A-A00:*D-4!AF=2<=564-)A%#@$F>:E"3$&G;36*2D;10.AG'"28.*E,C'8.9B5A7EFDD%E'(77?*069(B=76E12.!H4*4F+5!8:3D#H-5A%&B)514)3A*=1?=!!;%;=?*DD@)>*62B,H3
@r420
GNANCGACATAAGTCAGATCGGCTGAACTCCACAANCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACNATACTCGTGATCAAATCTGACAGTGCCGGGNTATCGCTCATCACCGGATAAATCCGGGANTCCATCCACGCATCCAGCTCTGANTCCGGCACCTGAGCAGGCAGG
+
(!'!(&##+&()+!'!#''*#&!*&*""'!$*#$!%%%%'$)#%$$$'()!#*%#$%!$#$(("!)#"&$'!')*'!*$##'&"%+&!("!)'%*$#$"%()*!'""#")#)"$*+'+'#()($'%$*+)$'*(+*+'#'+'*+$!$+'+')+&(#*#"&$%!$%'(!&##'"!+(()*$!'&
@r421
GGATGNAAGTANTNATNACAGCCTGGTNTGAAATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATANCGCGTGCTGGTTTCAACCTG
+
!$)*!!()$(*$*'*'*("#'*%*)))+*&#!%+$**&%*"&''##%!&$%('*&"(#+!#'*)*$%#))$'#((&+$+#$%$#%$$!""!'&)(
@r422
ACACCAGTGTAAGGGATGTNTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGG
+
&E):=.5?H+1+"%<2/F+A&4)?/'D742/CF.&1F"G<@6E3((2&%(-':;>-()-6@.*<.0!;(;4A9<,<
@r423
ACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTAT
+
4*?*=;H?6C@5EB5!;>BBB2>B1*@/2#:FB-2H22B$F>#9(HD5!CA?"5#&2:D=#5/-9",B"+&?0);9D!53.+%09/1*'A#/=)8<9E736CG(G"0/<FC5-1-@+,$'-2.*6(B=$6=%F&HD!F#*A,.>)74((E45$G->8>C6G?'GE..<5515#3+#E2#?-'*42H!77+%-=877E.%B059
@r424
TTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGA
+
A#:'H*$#&319(;H*7>&<"B9)/"*+;:.#=:547%1<3'$8&E<+A!H,)@#,;7,/-!?$-<619+:.-<)(<B!H$5#<0;F;/H808A29F)&&@-".C>$&2)88&1(FG8#'HE>8%A'-."$977)2176@91.%'501-F'7#83D#&<A'/+)8:E*1!*803.4#-:6(69<)3-*4G>
@r425
TGAACAACTGAGCNAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACNCCCTCTGGCGTCACCGGGCATGGCNCGCATCTGCCTTTACGGGGATTTACAACGATTTGGACGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTAAGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTNACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGTTTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACC
+
:8$?$18>F:4;#8D>''-C*''*01EG$5?8<;A?#&%3)7A(88%-B/0>4/F<>-@%3'6>,A;F72#+7C6<DG&9A;-*61H$**?B04?,<2-"-3+7=)&&GA<>!=2*B5EC>8/)F=6*.*7@D&:+H*#,&!AA1'%!,D:CE((A3($9+=&$4@*17(./%'E<B.E9,90<-#DGG@$B:?@$:'61+*'HDE;94*3D)3$3DG:HB4<1&?4F'-D(-#)C+4F6/03!#72DC5%C#9"0<?H;"G*@(!<<%43.*(1E9F$H)*'%F94"B0*<>=)<A:0?1D.>><8DGHCE(!G@,,675:9,$7.FAC/F!1;*D&6+%C!5>:=C"9#E8,/!B18AC-7&F*=1<%$,-:/'C:H>2!>0;82AC$
@r426
GTTGGGGTCNGTTATAAATTCTGATTAGCNAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAG
+
A79H17.F2,B864#D:?9-><;.!=(H0/H""!8F,*=!B</@<1!BF+(5$):-3DG:,4,3&#?FG=5"9/9952.A!A>H8:+0@FC%+;)0:D0?'H0>=3,HA6FD.+G,538D/:21E?:!8%4AD%,*,%7#<5=+D?/ED"H0"$8E3>2F#E=0D<)90D5>E;:>'
@r427
TCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCG
+
A??A:.8=G?::7?'<84,":65/>DF2>%FCC)+A-41-/?'+@D8$60D@;+(F:63A:%
@r428
AATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATNTGCACC
+
0;8+.G6(2DB9%>1'-$@8E,+.<<)@#4.2$@0;(D=EA3A41"::(,.:>=$?1<E(9&/#G#8/+<"<B.)B7G7D:
@r429
TCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTG
+
=B/32#E4F)2,&=>C1*G+%6-<46*=$B47!14F9ED.=A!>BC5)7E>147*33
@r430
GCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATCGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGAT
+
="4#":DAD$)@G/E19750>6&&?A5-@(@=!"1("H'H=,5)C-8>8)1:?@B@50@2,&<(!/,75G#-F"A=-=D$A2G-&9*?)6F0=25=H@F;AG*F);+E$A3$;-/+G%67@4;"'@<.>/*-5)A**3*:D8;!9F6-H29"C0@(#--01
@r431
CGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTT
+
&7E+:9C4B6/F%*"D#DD*1/3E#3H!@//$A6!/(4#*=B;6#E@-C2(%809G23&>G0H4;7
@r432
NCAATACNANCTNTATGNNCATGTGCACCGGCACTCACGGCTGTACC
+
"'&*(("$&!'$")%'&!"+!%)(&"))#''!"+$!#)#$''%"$*%
@r433
CGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACNGCAGNTCCGGC
+
+''!!!&"+")*%#&(!+*')#%*&$#)"'"*''#!&'&%(&+$%$*+)#*%(+*(#!(%")"$(%)("#)'
@r434
TGGGGAATCTTTACCGGCTGATGCGCGGATATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCAT
+
=-C5#3&"<,7!8%D?7)@)BC>,0":A/'+8A#8=8C8F%:$#/5@-)@4D$<)GA0("8:$3.>B
@r435
ACCAGCTGCAGAACAAAACGCTCTGGTCGTCATNCACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCAC
+
0?&0*D<>#$(:4HAE1725,4EB1DGF=:+C:1C!B>-=B#&%D529E3@GHFH@1?&?(*D,=,@FC$4B!6<--=
@r436
CGATAACCAGGTAAAATTTTCCGGTAACGNACCGAGTTCAGAAATAAA
+
9)'%36;,55F-*"!%,55E9>-&61(,?+'#B*=!:81,(CE<@8/&
@r437
CTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCANTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAAT
+
1/.&9'&,%H(4(;!BBF?(@F)"44CH.+'*H)(-:.H/#A/.DB8:%%C.#97G(B9C,045=H/-74';7$,)@7#(;??@8H=$E:D<'B/?348B@7AA3A)%<*21@2&A.G@=#B.E)7("'383(:!!#6)A':F1C*,'-1B7D5%F/:&%C;%&&29>"6C<A?H&A87AB+3A&F!4@@>D&41(A$)E/:-G#%G=GH<,-.3;;8!C>7(;)!',HE
@r438
GTTACTGGGATGAGTGAAAAGGCCAGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCCCGG
+
2/#<)@+:,B2B?/F2FC)E)<"(*3CE1,"GAH*?B$9'(;B<+G%5B:89'?G-C8>A"AA9>5.!9A)%:/@=AF"$%#(.38(8B3723(-A&9?F.*4G2&7:A$)GBE*%@
@r439
TACTGAATCCCCGATCATCTATCGCGACGAAAGTNTGCGTACCGCCTGCTCTCCC
+
<3'-G=(>#.))D!00E,D@?=?.26,.,37@H/E&"F*F2>/)6H33,")617D
@r440
ACNAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGANATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGNAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGNCGGCAGAAAATTCTGCCAGGGCGGCAAG
+
92)G+>8D;11#-*(4<<)"3$)$6%:E?8G?;2D,E"$.$*/(1&*857?-#8::-"2753&-#.+!(1!C'1+4)'E9B?3)D92B%'75<9#,0,=CD)/$>8&-=,$4#$(02?5711H%$4F)=G>9*:.&0=,()"%C/?9*BB::"(GH??B;&3$EB6D2CF?'@%A&B=!6/.(H;?3EG8/1>,;!@+6/
@r441
CATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGC
+
;.G?.7?<-'20!%C#2:C9=):.)G?7C7&!(!CC20:F0%=8&2>#G#4*F'B6."$21G@--,,
@r442
ANNNGGCATACNCTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGNATATTAATACTGAANCTGAGATNAAGCAAAAGTATTCACTAACCCCCTTTCCTGTTTTNCTAATCAGCCCGGCATTCCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCC
+
$##%"')*$$'"'+%"%"!#&(*!'+%+'#*(&*&#'*#!(&"!%&(+$$*#+'$"+'$$#%*($$*')$!%#!'"&#&(!#$%"&*'$%*$)*#!%%))$!'+*)('&"+&"(&$+%+!('*)#'!$*++!*""'#!"%&+#"*())#&!"+##!*&($"$&!(%#+'$'!&+(#)"*+'&)&"$*'(*'&'*"'')#&*!%+(#!%)#!&)"*'%)
@r443
TCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAAT
+
">A&D(#7!E.>.;4#BB:F4'3'!:5:5CC6:$(??3+@5@>/:
@r444
TAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGNNGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTTATAAATATTAACANTATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTNTGCGAACTTCAAAAAGC
+
6@>!C*$0/?611D1/DB!/*C'562,?&B$%+2$'-,B?8..(F"<'5-;*G=,@,/>D.6&9(*:*:.>A5'GA#''61CH#DE424..E",.49?F4FF.DC<*"$+F>H-=A*?(23#*&6C=+8*<76>D(#,:63'3B'"&<..;2?;2D8!(,'@*:*1+<7917+DF39=+)//,0G(2
@r445
NCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTNACGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTA
+
$<;G+4%@<F#B"1&9-,H3#>35F60GA=G4@A>95'$4;EH$C8+%F3/D922'D$"BBB>@=%7>@,/.D6B=*G@)!2'%;G00B4H@!$?:"0('1'5>
@r446
CACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAANATTTATCA
+
DDA-(,!):2&<$(3$);@$3;1$?H;''=,7#15=A&B*"??BH1H/F8%3D(>%"6G.%7:9H!,$,
@r447
AATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATNAAACGGG
+
2.)(G!0.H6??(/H6*@(2'85"!:H17F)4.C)@D$FD$!)B**+!3:0/$883C)#9E22:<!D>@F&#)3#;.#24.$3GBH8172FC@#H(**?F$9$5CD:%F/HD/=7'#('$-7$*/H7$9:%93G#?2F::3!B.>C=;A@9C!799/8A3#$CH"!#@500/-=/03DC7@'0,,-@*%&)#3C8""'A@+9#+8E9FG!;8H,,D=C3)>8
@r448
TTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCC
+
423=0/78/&GHA69/1E@''=!(4H(B<?)F#F,)2AAA9@9*C+?D"-+(+H)#1'8&=D,.G.'$5C%$%&#%-<B2B="22FBE('25$1'>HA(%,B&8.9194FB2C.+;4D)-67-C/5:/;39=&/$@/+*/'("6#1%":4%0:%>(55)H'C4A&,.3E%9!)GC;48#C$-;*<::(%-?&D
@r449
CAGATNCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGNCAGGACTGTCAGCCT
+
%F:=6:FF$6*H;,:*@+@C&?$,12'D6'60*8'2-&B?4,:;D"4!?*?729D7>>/)E"4C&61:0E*C/;9G55A.&GF.=4<3!H(8B>59>15)#/<%0;-*1GG0$@H&%$D;7<4.:7GE&HE8*>F1;8HG!
@r450
GNGTNNNCTGNATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAANCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCG
+
'&&(#*"$&*)('(+&!&()#()%&+"*%&%*$)"$"""$($%!('(%!#&*"!)"'+&(%$!+')%)+"#$#+*('*$*!%!%#+(#(!&'")+#+')(!!#!#+$))++'%('#)"$!+"&$#!#)
@r451
AGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAACAATTCGT
+
')&+'"%+'#!!%!#&"(+%!*%(***%!%(&"$*+!#!""*%')!"(
@r452
CCGTTTTCCCGAAAAGCCAGAACCCACTGGCGNCGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCA
+
4"%!!!2"*>7E=@(H722*'A01F2!$'/B&H60"1B0-;)2;$4DH9#<$.'!$!B9:>C$-A0BBG;C;)B;CC#CE0%7C67;$@@&="+3=8*08'D>=(6F-=?-(3H,?-:ED')49!9EHG5.C&%7=$BH1<5+B2HEA?G!5(46;G068><#1.=);G%>EC<#3E?=/1%.$D*C:!4!9'8)F>)>=$8>9<G!=5*&:F&46!"%!0!/E3,5)&(3%@7=:+>/4@$@#H398%C=-!-088%&"9$G;A..72./<"G%;A%+#.&)+$B9AG0=@2.
@r453
TTGATANGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAAAGCGCANTACTGTCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCA
+
E0G$B$F&H>5>@-$40H+DFGGA?0(;GE.+(D&4H)D/6;/;<1?FF8E#&7#C.#%$C14"?G%/-'6(B<C>"4$A!/@F-*+-@$#!-*D;5<7B-@>*%>188C..G>-?*2FH*C;!&G6'#!<F%8/7*+/(6B;1F2?G>H0=):B>8@(A;=E1D?<3;+80(=G732F";9+9C/@*@E4.#*F>8&H$5'7$87#21$F>>"$>,B!=F@5:.(#:&C"
@r454
GCGCAAAACCAGTTAACCTCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAACGTAGAAAGCNCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGA
+
:H97C*'G==H?.8-=/%G,/+FA98(@-&15#(;A(@4E"(G3!CFA3&54==BE+<(B%*(4:,G)&A+F.,.)G?<-:%.344<H))"7!;-8$%7!H%@*;3,@'77$'?08':(0
@r455
NNGGGGNTACCNGGNTTAGNNGTNTTGAGNACCGACCCCAACGATGAATCCGTCCGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGNCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCNGGGAGTGA
+
'(%"'%#)(*)'%'!)"&'(!)#$*(!*$$+!!#'&*('!$"%"('&%$((&$%('+$"#%'!)+%*)%!""'%+%!'&&!&!##+$*#$%&%!*+#+!(&"%&'(#'#'"*'$)&'($()!#)$%")###*(('%#&%+%"!)&!&&"**(%'&$+)+!)%#$'%#+!$!('$'))!&**$""('()#)*((+*(%&$*(*!*&**)"$#%
@r456
CAGGCGCTGGCTGCACAGAAAGCGGGGATTNCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGG
+
:EB-3+.F++60?)G)/.C?.F>950D)371H9828%@.B*=@<,@6:F.*#A?(+7:3B@<E(-14@C)48F';.5B=<2$0$/B0F;3750:54E*.3<0"#6,7HF"D#;F:2##).
@r457
CGTTGCAACAAATTGATAAGCAANGCCTTTNTATAATGCCAACTTANTATAAAAAAGCTGAACGAGAAACTTAAAATGATATA
+
0B!',$/&F8!5:%2(=!HF2;9?E6C!!8,56E5:$/>=:94&(;@.:.4&6;)>4EHA:7.!D+(7!4<D&>=;8"??).%
@r458
GGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCAC
+
B)84@9/69@4(C)@:A@1.3:+%#>?,=%5,EG**0B4>#3201#6=!CB3*FF1:C#9"#?:;,7@A94!:@?*.>+G*6>H%<"FCB)=D>28+6C?
@r459
GTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCTGATCATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCNGAATGCCATTAGGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTA
+
'+>D+%)4$+E&"0/<,%"(-F!"':9H0C:7+4#)28,0#@47CC,EEAA:F<@?;#@<3G+%%+(3??-$D0+',A,.49%.H:':(86355>:=&-:532FC?B;.3',!2:8A(=%>/3HA9$HG*9#H946?:8(%0C)0)764$AFHHG$?;@))::H(C&53>G?06>?../)$.??:6?!;AG''HF>0
@r460
NTCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTGGCTNCAATAAATTC
+
"+(#+#+%$*%*)##"#)*($&&$*"'(%('((#$#$!#++$'*&*+#%$"$%&)$$&!$&!*'!$)###(+%$)(&!"!&+!#!#%")"()&''&#(%
@r461
NGNCCGTNCTCGTGNTGCCCTGCTGACGCTTCAGGCAGAACTCGGGACGCTGGAGAAGCATG
+
"%"("#$!%'*!&$!+)"%****#%&!#"())+&!"*%'"&*%)%(!&'++%&*)%+%+''(
@r462
AACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCNCATCGATCC
+
@'5'%+7&-=67,G,GB,D7&6<"3$G9FF*E-?-7AAD//=;:3>?/F#EE!/G>GA.C":+B!:C<D<B$#>,%3356
@r463
NANACCTTGTGTGCAATTTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACC
+
4&6E#(DD>?>G$-;>3)E"B#AA22.*89F)91/CG>B"90#@2D(E!*='4(3F$&/$2!FB/#>B=<%E7-H=6?*D456@0-/4-+*,
@r464
NTTCCTGANACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGG
+
%&)+&*&(#)#&(%!%&##&('$###"'"('&&($*#$("(*&)%+!$'&(((#"""'*&!$)+*$%
@r465
GCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAA
+
2/9<2)=$#H#0'B1211C&H+?D@1E@94+H(8D>*8-#A2@B$8%?E<+0B8,
@r466
CCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAANCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAANCTGCACATCGCTGGCAAACGTATACGGCGGANTATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACNTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAA
+
>G")+('$5@=E=2:;D.E)7B%<E-0"G-5*@+>+F5/7F->*;8:*C(!#9%<237=65?>$5*5>!3%:H.%=:"2</<F#6$,66;'#@A:@A0,C81G(1:14%9AB47C.(*D8;&F#7.078"78G>1H/94@H>$.")%:4>"5A2F7'CH!,AE%-),@6,@2!96>G.-'C0@/40$=3>=!B,H@35<%C/F6)=/'>:(=E=0&6>#D!?"9*H#?+!-2G66*.8)C5#$G#>77H?3(893!;''%F;%,!''E%HH2".>/0E185A2,=6D4DG=0&('98&3"9/1=%!&?2DB;+B?A9DH":5@A#/)!A"2B13A2,:G#()@("H(H$G"4E4?$#5*-24F4F<7:B=#0$!@-@)/>E@>$1-C21+;#->0D4&H>C42'(<4$?@,,*E80EH?7=1>)A=343:>.C=2#(,1%>D>#+1$F>7(C*!2
@r467
NGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACG
+
!-E&;=8>C="3A>/#-7E?529A))$>B,G%98*5,>1.D=F44(2
@r468
GCCAAATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTG
+
H:A+?;A9E>E"&C6?%&<'4F",D3.9720/"G1<-*&/,".>4AG+=HB78#8%
@r469
CAGTAANTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGNGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGNTAACCATCTGTGCGGCGATGTTTTTCAT
+
?F""!*%H#<G)7*&9DC:0$!(5-+4@B>88>G7&?9F+?=%;E2A)C1$90?@1+(-5)"5?A!E3$9!%!*51)/H1#/,*'F&D?ABF;AC!;#C6C9!0:"<65E8H)8H2,!,'>?A0794/9=>18E++<847)@)%
@r470
NACGNNAAGGCATCCTNGTCCGCNAATCGNTGATAACCATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGCANTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTG
+
!$)%&"&&"("&"&$&#%(&#'$%!#($$")!+!$"!)"!%##*%+!)!'%'(**#$*'%''*("#&"+"+**"!##%#%#(+&"!&!+)&#+$#"$+*$)&)'&'+"&&)%))%*'$%''&+!#!'+"!+*%+))*#*$'()+$$&(+*(#$+!+'&&*)&$!)+'#("+'#"#!'(*&')!"$*"('&+#&%+"(*!"&"'!()()'#("$$+)!"$&%&#)!!+)$*#
@r471
CTTGATCGCTACGAAAAAATCATGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAANTTAAAGCAATAA
+
+%H0#7HG+-HC!%(!(E"D$"&G"F?=A<&&*)E'#.+E=28/B"F1.*F,>@'';;(B1-;C+(3#=FH8*'0C+;23B7A4
@r472
TGCCATGTGGGCTGNCAAAATTGAGCAGACCAAAGACGGCANACA
+
HF0@G)78"8C3F;3+(E,7FG7!A$>EF;1-6:?2'3/AHA+'(
@r473
GAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTCAACAGAACAACAAAGCTGCCTGATAGTGGCCT
+
G=)+#0'!/!C4@*+23HD.:A&!$%B-$G25D2:5=8G'6;$:G.8%@6A3>?/?6)<2$,EE*>B:'?.%A@#8'@?82GA7,B%?44)+@&"?1/$D%F?&%@F&F+6;241;&B(>:/.H#3(!"32+>>%'F<
@r474
TATATTAATGAGCAGTGCANATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGANCAATACACACGCGCTTCCAGCGGCAGTATA
+
D:-<F69+DG159F-BE0839+3,"HG8,.B%(3F"%1*;3!1-:DA@;'?*C5/@,-'(-F:&AEHC.@81@@D(?&:G?"3,,3(+(6!2=F-
@r475
NTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGT
+
$>&(:.=20.6,'D?:-&*#69G=ABB)64H>(554A;D?D:+0>%D0%3.@;+:HA$7B=D*,&*5$-HE?(
@r476
GAAATNACCGGCATATTCGAGCAGCGATGTCATGCCGTCCGGCNCCAGAAGGGTGGGAATGGTGGNCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCNGGTCTGCACTTCCAGCTCTGCAATATATTNTTTCAGGTCAGACACGGAAGTGGCCGCAAACTCNACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCNTCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCC
+
#""")$+)(+)#%'))(#+'+%(%#%"!#$"()#$'(%##+$&%%)$!$+&!"%&!"!$#&%##$+%'*)*''**+##&)#*$$%")'*)')*!'"*(!&%'""'*&#!&'$!+!#(+'#&+#%**$)*$*)++**&%+)&'*('%()%!""$$&'+%##)+))+*#)#%%+)*('*(%"#!%**#+*+(!"$*%$*'$!"("(!#$!!%($"%'*&%%*#+"*"&)$*%*#"%)&"($%*$'&$!+(&'&"(($#%+#*'+(&++)
@r477
TATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTC
+
.4+@@BB1&1E*B/#H5>4?/G&>="#?*BHC+GB284016=#74A&8+'<#H?3-;8.A:5/>?:CG4
@r478
ATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAA
+
2;5'=@6.F=%&(43CHFB7*>3$<F=+F@GF!$B>?D:#/%?H;96".
@r479
CAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGT
+
F5:@(?;=#2B-,>D.#&584<&#"3.7$@,&80*->D1C0
@r480
TNGGNGACNATGTGANTTCACCAACATCANGCGNNNGNATATTTGATGAAGCCAGGAGAATAA
+
%"'%'*(%#$$"(!(&"#*!)*)%$'(*!"#($"%!'$''+(%&%&%($'(()(*("#)%%'*
@r481
CTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCNATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGNTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACG
+
<%B7/+0.C&F.31)#9<)C6%:!.B3:5276$+5+=FB$'6&<'-/*HA$,,6?=/$G3@%,=:>4E-(8@81D<3-DC@E78+-7A-C<'"'#G>'(F8F8@B9%!#0351B$H?=$8:<1.:B6GD43<H7F;9.F(*5!49C;#;0@>!'FA+%'2-<G81E>G35,%3!-5+HE!%'2<B1F3:,((2E:-4BDB<03!9/'2C&;0H41<.-;=C(66%:E&%
@r482
NNNATTTTTNCTNGTTTCCAGCATAAGCGGCTACATGATACCCACTNTCGACATCGGCATTGCCTCTGCAT
+
)#"'"(#&%$'$#*)&(+"$+()'"%#$++(+($)&!+!&&())#'(*'")&+$#$(""**"#&&#+++$)
@r483
TAAGTGCGATTCCGGATTAGCTGCCAATGTGNCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGNATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTNAGCGCAAAACCAGNTAACCGCCCTATTCTCTCGCTGAAT
+
)DBG8G?G3G*1D!B3#-0.G6HB/;8()<)(3+?:!:83A&$=AH-$*%/CA&84!!)<A!/(->'3F5-.<-596,(;F.D?;21.!&:./?<"0(-8=G!!DAA)7!A%2(52&.G6"29#C4?B%2=">G$'/C+0"55>1/'!'5?145F(D!HD&1,-#2#=E-F/3;=6EC=*9.7$:@&>*A/9#061B&),./A$8&=)F>(%>8)'>H.<F"*+D*#
@r484
ATAACAGCNCATGACAGGCAGACGATGATGCAGATATCCAGAGCGGAGATAATCGCGGTGACT
+
"+0C7G#B?EDB<"2D+=*"2&,3+C,5:C""<8E@4&5E5:#@AG76C)53=(9E#?<(8")
@r485
CGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAANCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATNACCTGGGGACGCATAATA
+
(!C1?0"!/E">",0A"B@)F<"CGA@/(D9#9;+*"6;"*H">?GH'*&-<?C1#;9B5%'A9:/9.2G2)DC@1:?!:A=4,3#G76)$1-@/4&4%+A+A46+$/!07<-*/!%/?%/8;2+503"H45=9$"43D$%+*7*'.6HH,:H;B<+7=&5(FF282BD,*<6";')/@D>0'D?<:.-*0AEB5;;1.@$D&#D53@5/7D-EH%8A:H--
@r486
NCTGAGGGGGCAGTGTTTNCCAGCGCCCTTCCTGGTATGCGGNTTCCTTCGGGNGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGANCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCNCTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGNTGATATCCCGTTTCAGGNAATCAACATGTCGGTTTTCCAGTTCCGGA
+
#)**(#$'))'&*+'!###%)%"%"#!)&+*#(''&+$)*#&&%$')!$'*(##+!""*+)")&#%&&(&"#(*)+*")*)&$%'+'''"(%%))$++(")+$!$)*)())#&%#&"!+*!(%#*%+%)+&!#'(!*%%'"%!"!(#)$**!)%)&!#(*$"'!!'(&$$'%$'(!(*)'$"+*$*&!+'""$($&#!(#)('+#**)!&!++*!&""+"#*"))$#$#')+&()&%#*+%+#%(*(+)''%!+"!#'!%%!(&$$#+*!
@r487
TGGTTAGCAAGTTACTACCGGANTTTGTAAAAACAGCCCTCCTCATATAAAAAGTNTTCGTTCACTTCCGATAAGCGTCGTAATTNTCTATCTTTCATCATAT
+
35<70!05;E&2$@;H!+**0A)D#*&60"F4*85!62)*?%G@+*0-H+&5)%E+0C<+(7=HC%(08)=62A.E5%04)?1)?51>6.="F9;C,$CG+1#
@r488
AAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCANAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGACGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCA
+
<)=72".+1*@HA.>"8HE#F8.8.(=H7%/1BEA"BF1H2**0;B$D7C98?G1F7GB8.&?.!5+"3/>9:B++'A*E702:#'<81.+!B$#8<,7B'#<<B4!EA?,6#77(918(<:+0+@2'0)B<#44F@9,'A.HG046$@%;=AB20#3=',BE8B$'G=;=5*$)@;<6?>HBA'0?*F:GC697<4F0?7.!*(4HAE+5<1E4G7
@r489
CCGCGTTCTTCCCTTCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCA
+
&+$!3GC+;BA!-&/E23'A/72C$6((;0?8<F?#&910-7?B8)4/B.#7B%4#
@r490
NTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCAT
+
%>%#/C7$02.CF/1BH:<2/F;>H?3-3=.6F->7H)<=9F'>2C8H9>*
@r491
TTTCCTGTGTAACTAAGTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTNATTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAAC
+
$A%(1H>%2"1?9+F016B3E5?1+7!3'<94&%0$5>#0.)920G>E'%=":D#=<E/>&)07%1@9<96E5(-:06-C59$,4"<&?',-*5,1833*$7%2$.=G'H<':#%-4+-@*;75.C)+;*C
@r492
TGAAGATCCGCAGAATCNGGCGGACCCGGCTTACCGCCGCC
+
+=!<9*3.EA72F@9#C>H*D336&)2E/3A<'E+$#%:F&
@r493
NACTGCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTC
+
!(!&%)#+!($")#'*%)"()%%#$)%!(#+"%$*&'%**(#!*)"&(+'*!)+#((*
@r494
NNNAGGNGACCGGCTCACCTTTTTCGTTNTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGA
+
!$##'%!)(&$!)+'!"($"'&$$)&((!*%$#*)%%#)'+%)&"''!!"%(*'+*)('"+&%#*$*#+&%($$')!*
@r495
CAAAACACAAGGAGGTCAGANCAGATTGAAACGATAAAAACGATAATGCAAACTTCGCGCCCTCGTATCACATGGAAGGTTTTACCAATGCCTCAGGTTGCCATTTTTAAGGAAGTATTCGATCAAGTGCGAAAAGATTNAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATT
+
227#17$.7H$';4C",4:,#%2#1./=.F'!=,,"!"H,$0EHH7!/$67.-5C'!@:6'9&2@+;289D<-1H"+6&!(-H@.2G(;,@&H5&=DGDHA):#9@EF6=E-6@3@E#!<=?6#-.H."8,-C5&A2$13B"$&C7@G#C/H()8-38H2*3.GB*0B426-D!4;,/G>60H!&!3@81@!$F8<;%:0+*/A;)&=6<2F/<38*.G
@r496
TCTNNCGCCTTCGTGGANGCCGTTGACGCACTCCCCGCCGCCGNTGTTNTTGCGTCTGCCGCGGCAGAGGCGCTCCGGTCCGCTGCT
+
')%!"(%(+)')(&%*!**%+*++&#+!!)!))&!#(*+*!(%$!$(%**(%+(#(*)%%'*%%&*+'%%))!%)&"#*)%*"'#%)
@r497
NCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGATC
+
#6'<$98.!DE<9-=<(!>$*)"!)DA"&8A3"$CH#88#A:&
@r498
CTNNNANNGNTCNNANTANTCNGNCTNACNCNGTNCNTNNCNGTNGACANANGNNGGNGAANNTNNNCNNNGCAGATGNNNTG
+
$#$!##"!"!$""#!"!$"!"!$#$"###$"""$!"$!$"$"#!#"$!!"#$#!$##$!$"!$""!"#!$!#$!$"#"!!!$#
@r499
ANNGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACANAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTC
+
'#!&%+++")&!'%(&'#$+!%##*$)$+'')*!&($'!"$$&&"(+#+&$)**%#$)(&&"'''"&(*%&")%&('**))))&!$""!'%)(*"'$&'$+&&""&*')*#')!+$+!(')#*+!"&'
@r500
NNNCCNGCAGCAGCGGGGTCATNGCAGGCGCTTTCGCACTCAATCCGCCGGGCNCGGTTGCGG
+
&#$)*"#*(+&+%$$"*"*)'#!$#+(+*#)!%&+'(**)!*#*)&*&&&('*+"+!$$')&&
@r501
CCGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGA
+
-E+&"?C.4+;D>7,'2A06%BF@=FB($/B;3('B?)B=45C%"
@r502
AAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTT
+
><&0*""$H5=$>@3/<B)&50<46$>#2"F@?AA05(>CGF*DH3!/2##'/D8+,H/2:&4!F#F1F$76<C==10:64&8;.,"9DG7)768%<GC%!52
@r503
CNCNNNATTNGNTCTTNNAGAAANTNGNTGACTNTNCGGA
+
%#'"!%#)&$()#$#(%$'&*(&$"#*$()**#(*!%)))
@r504
ACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCGGTGTGCTGGTTCCTTTAACTGTGGATAAACTACCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGA
+
<?14%C.D"6:>@1>:'/(1#,&A$A302C@)"9/<B1*CF,!&3,A/H8-9DEH&:$B3@$+''898F"FE<G"@7%:@*##!7<,*">EE5."2@!)9:@#E3:)>84.0DEG@&EE$3):7:"A(6C:%!!5-<2)B&.155$B7*4B6")=FD.E<<.$4G,<<'=;6&0;*EA:@?+9:!/"F;0E!A*5A&1CE:5%>C5D(-H'<B:@!2'G+>
@r505
AAAANGTTGCCAAGGATATTATTTTTAACCCGNCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAATATGAGNCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGNCCATCT
+
3.-2EH)C%E47C&*G-A)%4D33/97BAG#4"?)DF?<!'C()*;@A61D")+.F12*!<5.#%H/;!38@7.9=C&B+.(-5=H*@/D!'/F*0%:;33=47"=H$,B>?+#)@<0$1$
@r506
TTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTC
+
&.27=8:D;9=F3@E$43"2F1A>-*?5C848;:!C3H#=-E0(8EH?*'3,@'/7
@r507
TNCGGGGAAGCGGGGATAACTTCATTCCNGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTC
+
)#%$()''$*+!"#('""*%'(#!+("+$(&)''+++%$+"%(#&$'"$$*+!+&$)#&)&+('&*'!$*""$()#!!#&!!+()!($#$!!
@r508
TATNAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTT
+
D@8(FC>-E8B5/::(::2"0.,?A$#HD?-#-04C72E>17-7:"&.%C.?E%67G1:;<+C
@r509
NATAAAGCCCTTCCCGAGTAACAAAAAAACAACAGNATAAATAACCCCGCTCTTACACGTTCCAGCCCTGAAAATCAAATNAAACCACACTTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAANGCTTGGAACTGAGAAGNCAGCGGAAGCTGTGGGCGTTGATAAGTCGCANA
+
&(;'":(=8@%,G965&!!-.+;+(<8=G@C))-&:H4F-B.@(9;;;.A?2FHFG;5<7:(.)*">A%3E0+-33#A%1EG)&0F-5"-=%*(7%"063<+;(C5!/7;D>%@/>01&@#*>(1/FA.7#5C"F&2)0D@@*:)9#;6E$)>)!925<+.;,$1-FE,C"GGB2,('7-@C7!/8F%6:!?:78DBB!)+E00:1("+8BA71>1<-!/%&;&,BF@7%''=::A9&B-,8;$",:8%><)/3HC!9CF7HA1+14=&/
@r510
ANNGGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAAC
+
(&!$*(+"*("**+!(%!'"(!''))!&!(&!&&$"'(#$(("&#+#&&##!
@r511
CGANGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCT
+
8A.G)-<G-7"4,A/#F."D((@'>*#H9"4D=6*4&C#1AD(,GA,H*(&/AEA.>E3"%G8.CC29E4<#B<:F=F**!',E=:5.B$4.6%&EA8,A@FG<;4"$$#8"4=9*>%&H/;)G%&(A%H*&%49E79;13>3F:$')"<=>$&FA$88:&3%=E@#G&4<0/4,5B6AD4E%1%>G144C"4&"B&H0H6/"<;1#;36
@r512
AACTGANGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGTATCAGCTGCTCAGGTCGCCGGCCGTTGTGACTGATGCAACTGACTCAGCACGC
+
DFEC&(A>D=+$4-B,290.)'07-$G3*D+3<?4),4>E,(9';$D-'?8F4G-,;1&/=2.AD*=6?5G.-B!*A?2,=,'&#>#3>4;(/58=0(HD)1/H*%,;"%>*96'!A)3@0D4$!;=G4$033G/(@!;@5
@r513
CCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTNACCGCTGATTCGTGGAACAGATANTCTCTACCATCCTTAACCGGAGGTGCGAATATCCTGCATTCCCGAACCCATCGA
+
D:#;2%>:=01D@!>H@CA?8.2"F6G%#<3?0'0*,.+;G%".:H56$7<;,0"%!$##/6?>-2@@92A.>>6<6$H!@"9?/.)4B2CC25837H>)>+2>7=A8@<8/17)!4*2-!/.75*'>$5#'$67-8A&8%F(<H<#0.28$$=B47+#'#5/19$H($2.&F,G>4->74&+2:D39>/5,-A+;,FH24%4,C;B!A:+2=-'/4+"B8H1>5
@r514
TGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACCCCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATG
+
C>1$&C7*7.5B4=C3."'4A(=8)9316A@,/9":<EFA2H&/"'.<4A/HD-5*7:"*/A"8B?7H>C-6C<DD=B?()"C$A:?$).?&>:B%=?*/?E/7-!+-H7-7$G2(;F)D+2:-.6&?BE*.-3@?70!38(!/%'449<#6*0(1C(%&/@*!?(=$
@r515
GCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTG
+
=EH)5=2-".);)0'G5=648"$4.0666;+#E48.%H97$D842++D)&*"H0?@D61F%6;*:66F*/6(G"6%H(=8?/;A$-92H6%82&'019@9@&2>FC4'0
@r516
AAGCGTTCATGGCTGANCTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCANTTTCAGTATTAATATCCATTTTTTATAAGAGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGNCGGGATAGCCAT
+
D)4(9/*7#F997>=H*H":!3<<2%B>88:!1):B?1'4=?19'%4-@*8>2*G'.8./#7H.??,G3C138717<=F@C08.*962#D7+2BCA;-'"F!&=C$,&)D4(H.A5::;3;)G.!#(!)8&D>2=".',<9+4F>55%>&<+4/$?38G>*#(*G@<2+--$9+6%@.H47-+81D?B*<=;/!D%+5&G%($&AE+2$G*',
@r517
GACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACG
+
@=A85*.-6"(>,G.(=6?)-<G4#H@,.A$B&*0H3/$E#(+>34::/A6+74;4'0A"4-<7CD,
@r518
ATTTTTCACCTGATGAAACAAGCATGTCATCGCAATATGTTCTAG
+
:0%7@?HG"8C-:>#:H,=4,-B?0.07)+7,%(8H*HG(873/F
@r519
GCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCNTGGACTCCTCCACAGAGAAACAATGGCC
+
'>">D(*&4=C2+H'7H/=9-:@AH$*78.>9F4BA-%1H2$"1=/798,%*#*F='&??A7)-*/!1(>2H5==HD)H3+A#CE5'C@!;#38/31+H+/+@3(@/7H($!B92=3D4
@r520
CAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACNATGCAACAAACTGCCCNGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCANTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTNTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCT
+
A5C#:9@A$!/D9@9G4B,C2'66,76%!:?H2#3$@C"C"9.%):,B@9,10G"-=;:DE4F(H..)$<@8#%3FH71"B243&/#;2E#)%(5E55H;A"EG$;"A7#+EA"G=E#75B2+>%G;%::F3!%%4>,<!/5H7E#@(!:"'+E&/D&-),?.-B3EC3D(G9%/3*-;)!)58DA!&A22D;-2?.F/'
@r521
TTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCACCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTG
+
'++)'(()'$%#(!$$('&)*&*$#$%"(''$#+#'*+%(*#&$*+"$)#*!+&$$*&!&$''+&"+(*$"")"#'%!%"'!''!%'$!#)"+%$&%'#)!'"%+%)!(')(&*%)&
@r522
CCGTCTGCGCTTTACCTTCGGTGTACAGGCACNGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGT
+
(:AD7<D"",<;AC=E46F9@@."+FF4(13<%)E6(;$CF)=$G#5?$;5@:-0/7)E2.;;6.-@E
@r523
ATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATAC
+
>61(*<-DF%?0"!64(!C-F!*/21<9G$;!@E%/C,4H1!85,7-;A
@r524
CGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTT
+
G%.>,/;?$<EA?B"A9/0FG(0H@$B#.!$)1"&%17<4!1A=%-F30)+:-G#877F.=91D3?F,<H$F,0C3&+D*+7:49GD0-=-FA8&B#(E=.&EF%CA=!0'"3H#8=5D/,9B1@,)'7:;15F77B&54D:>0H3(?$>";#>>">:F>2)G1,+74>@E(>"8E@D2F;H-DB/5
@r525
AGCTNTCTTGGTTTGCNCAAAGNGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCAT
+
*+"'""")'$!$"+$&#!#&")''%#(*!$&*(!#%#+)!*'**&#(''!*%)##+))%(
@r526
TTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAG
+
/H)9>''?-64;5'A.222)/35<@><@3EBC""93:*232'4H0'E"2F9#9B;/8
@r527
GTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTT
+
H4.B+2@7:9@$E7EA;:4$;=H!69%'FF&)!$.!F27>->)C,?F?<@;($G!E3.B)!#G;*2H
@r528
CTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATG
+
A0=!'BGFE!A16C$8(((D4$-.0"656G30@D5.*!2H1+(8B=C.$-&H17.?++;+.3*63A<89(0%:&<&;;&046<?5<='-;./70:(3;G)1@3G=.%<6D/1!.)2<6+.<8GD3C>!9D2ED@)E
@r529
NAATGGATCAAACACTTATGGCTNTCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATANTGAAACTGAGATCAAGCAAAAGCTTTCACTAACCCCCTTTCNTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTGCATTCAGGATC
+
#;2B1#$.G%2(CE8.-E?;:G((+@80#9-*+>E6=%5%!2#,)#+31>E.*#;$5/908E:,?3,(D/>40"A2GF8%2+-3/<=G".2?H?4@=%C7<10)H8=A3A#,7#4D>-8G4$:5%H67+E,#.1#6?F)FD!20E2@2>.#FC"%@G0"$3BE/D3-E3')"CHGD%-C@@*/?5H89(#C=D1,D(:HEA3>#+1/0?D"0#>6!#6440(G8<9?)#3(@9(3&>2$/6B9<)
@r530
NCAANNTCANATNACNGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTATCATGGGCGGTAGACCTCTAAATCGAGCACAGGCTCTGGCCAAGATCGCAGAAATCAAAGCTAAGTNCGGACTGAACGGAGCAAGTG
+
#$$"!#!)$&&(("&+!$(!#*&++"#*+#$#$#())'$'&'$+*!$"!%&)+$'&&#'""*#"+$&&#$!(*$!)(+&&'(%$"'&!%%#%+%#+*)$%$*'!!*+!$""$''#"!+($('+"&#$%&($("#%$"&'"*%)!'"+%'&&)+!&
@r531
TATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTACTACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGNTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCG
+
3E"/EC)4'9H5%1)A%/;;A34>;,BG2-*B38A-4318?9$:$%4$5"B4B")5)#G<++C<EH21C"3*DC)!>3&B:<),23:(")A<2C#BC-6,2C.D'7-$8$+(F8GE#/48(6'B=D.:7<*@3:?C:=C>%B=B9#7@G@@#"32!='7>=(#".B"$'>%&?9*H$5A7'=1+F,55,%G#)!E>E2GE%9-G7:?5;$.(:)"C1)C&D'>"F@=*';'(?!(88#$+(8F.(
@r532
GTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTNCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTC
+
+&:C79-!.9"(G4>&F4:-+!A"F1&.)73%D>#/2+&++3.-0F6+-4,*+?;BG4*/'4"%-B$$G7.6$9,&9<C:6G=DA1=25A#C71F,DD>E(2+
@r533
TAGANNCATCGTNGGTAAGGTTTTGAATTACTGACCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCGGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCTACACATGAGGA
+
))#$'(&#)(!%"!*+&*'%&!'$"(!!!%)&("'"'"$(&#++*&#(#+'*"#"(&$"###(()*)')("'!%"&&**(($%')!++'+'*$*'&$)()%)('*!"&$%'#!#'&'&'))"''#((&)&*%$""+')'$&!%"%!'&&!$(#&(%#&%*&++!!&')!&*!+*')
@r534
CGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGT
+
>%9">"D"<%D0'6G:6?=CE?0<<>1=+-E(9$?CB317872);B(29F>;9:A>#A$9=#&&
@r535
TGCCTGGAATGGTTTCACCCTGCATTCGCTAATCAGTGNTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAANGACGAAGTAAAGAACGCGAAAAAGCGGAAA
+
E$'#H6?9225!B<&#28E9C8(#H*$#>5)>5<1.91D%-3,'&.H7<.3+>17>G29?FFG8;1C#'7<E#D-3F6(>D;D6'8!>,1:84?E.:+4:5<A!0)@*!
@r536
NAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCCCCTCANACCGGTCTGCCTGCAAACAGTACCG
+
#H%@3=AC(H*@6C?1A5>=-0E3-22!D.HA7HDA19<,8+;.&>?@H4#E'*5%,=>>95,(&//F@+B1>+(A)&B#6;(9G3@%;("<A3>*!HA:7,5<B3CD#
@r537
GGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTGACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCGGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCG
+
9':)>DED7+99)*8=@C7*$)@0@E?D&29@2@GB)H!9(:,.C$&D)-G?)%H96'&25B"@2)('237&3F;!0BGB0-,E=-0*?80E3$5G-0>H3791A;$C-;?#G'&@&68?1$4$>#A'6*G")7%8.:$D0E@1#G=:2;@A?(G-142?5%+A%3E!E"%?()2
@r538
CTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGA
+
?B0$.':0D3H+#*CD4->EH=GGH&H.0;?(&:G!2">,$#?6>2:F!=*>A
@r539
AACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTT
+
@,D%E&/@*/#+3$@HG@?93E*G3"3G!G9=@9>"E;4"A?@B8+>@$,&6GEB#;G>=C"$>7A>$6"$,:
@r540
ACCGGATGCTGGTGCGCACCANTACCAACTGGATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGA
+
6183?)%A./0C6$5!D98-=AD4+$.$DD03C!*!*8!478/&)@F1,!H#996,-3<%5.C<932B@/E%)&H-:?
@r541
TTTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCG
+
)<E?A++$7;9'CAA>8G>;--%.G*83/4?&->D)!E8C+6<8:
@r542
TTNGGGTTAATGACTATCACANCTTANTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTGATATATCGCCAAATACAGGTAGC
+
$$""*#%$%)%)%'(%$#"&#"#(&(&(+#**""+(%"%+$*&%'&'*&!*'&*!&"&("*%'&!&$!'!%#%+'!'(&!%*(%"!"(($%*&
@r543
GTNTNGNNNCNNTCNGCTNAGCAACNTNNNANNCNTNGNNNNTTGCTNAGNNNCTGGNACCGNNNANANGCNNNGNNGGNNCTNTTNCCNNNGN
+
$""$$$$$"""$##!!$!"$!"!#"!"!$##!"#$!#$!!!$##$$$$$!#"!"$"$!#!!$"!!$!!#$!!!"###$!##"$$$$""#!"!"#
@r544
TACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCAT
+
-*+F-$5H5/$@:GG,.0.FB$#273&#F#;B#B(A873,9*,32#B*E;;2"EED$)>)%G.2
@r545
ATTGCNTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCNGTTCTGCTCACTGCC
+
,H$'C%#-#=50"4*.HG)8;2@9&'&HCB/'F;?-#.1+=/H=2@&7-*E,*-$1%/&(?4@3<44.42?)6=&#(
@r546
TCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGCCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTT
+
HF-"(3C8AGB12<D*!B(&<1-""(-@.,&<<G=A$4#+%"5"8)??@,6/(8<9D'</08(@>2+(@;3CD<6(A10@FE*/2:?+>!&%?4/&#&-91*/'*('39%)584%,3)8:,:96G@+0'CF*F>GCB.D#FF7$<36,)$.=1F>44:4$2&2+4+
@r547
TCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGA
+
-.E-C!B#!$9"'F6!.<5GD1418,3!3(7)(,H(H34;C=%:(>/B67%;)03=$?G///(11#%5#?,&8$,F1:A,!C:D7#D
@r548
GGANCNGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGG
+
$##!)%+!#)#'*$(#%!%&#%$&+####(""$#(#*"!($$"&!(#%(#"$()#+"++*#*(+**"""
@r549
CGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCT
+
9<!5==?0/8C=E7GG,#'/4824'+:=$.?*.+BB977-5%?C):(@!47%;H;(/0A5+8.C<3"$G7B(+>;,60A:!;FD0FD%58-.G2?%9%E."F=)9,50F(>5<EB#(*<!CD1#D(*B+*2G:A!@G:?80+=#*!
@r550
GAGNTNCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATANAGTC
+
%$#"*'+)##*!&$")%#$"")(#'&!)+**(%'"#(%+"$*%+(*!$)%)$"*+'%&$)#"&"&(
@r551
TNAGNAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGNCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATNCATTTTTTATAAGCGTCGACGGCTTCACGNAACATCTTTTCATC
+
$#(%!+(%'""%'*+*)('$*%"!$"'+'!**%'+(#&+$(!*+*''"$('+!''#"$''&&&#+!%$%)&"#"%$!!$&##(#)%!*'$&*)%*"(&$'#$$&()()"*!+)!+$'$$+*"*(+('"%%"$&#+&"&&##)'#"*'%(#$++#)%&"#(*&#&(#%!&#*#("$
@r552
GCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCGGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTNCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCANGCT
+
2C*C#7%#'50+=:1H5F5$)$@#AF">E"/E+4'@"=.H)*9#/G">A..DG)7A4@1B8&G41'""*=27+%+!)A($F<@6+5;@A-?A:0G'2D-F28.3)C%5E(G75HE(78(0?2.*60"A,!D-=E,<!@$=D?(4C=@0*,55*C1/+G4%@5AF!DC$#(<'7$D;F<7@/C92>A8-7&.1=:6<2C$0H&D5H/</.59@3EF#A&>.A>E*$%
@r553
GAGGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATG
+
013.GA.2'1$,E9;F=93*/A@E429*;$#3*0"/(GF!D7+;%4;8(8/
@r554
TCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATNGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGG
+
>EH1;+?-H4"9--<"EBE-)6/4AE8/.-$5@@C.!"?:,H1:2"1(G6-B&->79CG<6A+;>EGD;)GC55./8B&H*,#;*'4-2&9@*7/!#$-"'G8&%:28&D(!3=4:20+<>:.*)'!%:*%@"''B:@F/?"(GDD-$H@#!<G&*3A"B!>F*H!D0AA,EE;B<F;&B&-'(BA8'7'D-F,D<@A"@$3*9E=/*%0B2C!9G1;)(EDA+)$E#71"A*(>3FC)86:/F)/4GCB9;$/8%@BE
@r555
GGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGT
+
2<F"D;&(6AB:,B@G;3;"3D":1/0B292#)$A466%H'<+2)D-;*+3(2FA+DH)61A':'94D61@;)(@(997(B)E<A;)%E=8?B.(8)0
@r556
NNTGNTGAGNATNATGAAAAATGCGATATCGGAAATGTTAAAATTGGTTT
+
!"(&#'(*"*(*!"++'&&#$%'""()$'%$+&!)#!'*$+%+)$%+#'#
@r557
TCTGCGCTGCAGTATCAACTGAGGATGGTAATAATGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATA
+
%*142GG,71,4*2>E3"!)7H5>36>;:">@6970,?HF$E+,D@F@:)/:2'-#.%$;/0"(&C@"DD$7=FG
@r558
GTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAANGCCTTAAACCGGAAAATTTTCATAANTAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAAC
+
"072(-H!B$?9.(-33:B2/,2%?=>8G7D832-4&7/%-,BH#!7H9,,;'.(*H8:((+F30=28(,$.1&/0-5E@03;C9(-=5*$510)B1(">;:#4:F(*G*))AG67(D,*1=A6&%*"F$@-#:+%*DC)8"#03++A)/A*$'H)!-1%149D@#1A@2))G$>G9:
@r559
ANAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACNGGTTAACGCAGG
+
0,5$5.BF!D-!E$0..*46@3AF>='H=EG6F;?+"1=84G01C/)7&%&??1=)10:7)(F(.%B"92C#6%EF=/BC2:.$8
@r560
NTAANGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGT
+
&"%')))+#*#$("%+#"$((#)()"*$"$+!+*&!((&)%(+'$'#
@r561
ATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGNTTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATC
+
0(:4=-$9852H76;/B2?(E%3C04*94C'0$:8&B*604F2+0=@7,A-7D2/7-F,$D))D0*8;=221;0(43%##,2#A<B.;&(91!,'7=,;/'-)?C@4/&;6C/D24G=@*"D&,;6=#B=$2:D&*;&$3'#E:+('!-?F8F%*?'?0-1%8804>+F
@r562
CGNCNNCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAANCCCGGCGCTGCTGGCTGATTTNCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCNCCATCAGCGT
+
(""&"&+'$'&*('!#*$*'+&'("$""(&%&&%')$'()*$%'!"'(+&#&)&(+(($)!'%+!*&#!&')+)(%#%&##"!(%)!!%!'!'+&#$(("#(%%*!+!&$%%($(&#)&&$#$()!+'(%!')*%'"''&"(%#&%"$*"%%+("*%'!*"%%)'**!&($!))'#*')#()'''$&+&&!)$++&#)))!%(&)%##()!(!#(("%%)))$*'&*'(#+$)&
@r563
GTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTT
+
<0932AHF=!1;)C*9*A%G0@294*8>25<5$)6:<#%E9@#$F3.$1=(2H,>6GBH(?08
@r564
TACATCATGAACATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGNGCCTTTTCCCGCGAGGTTGAAGCGGNATGGAAAGAGTTTGCCGAGGATGACTGC
+
'!#("$')*&!+&*$"'(%+"")#%%"%(!%+'++*(($'($(!!*""''($$))*(#*"'(&!**+)**(+("))'!"&$*#(*#*)%)(&%##!(%&+"+*'(!((!!#!*"#"%%#+&+*$%"+"$$#'$"!$+"&#"$#
@r565
GCTGANGCGCGGCTATGCCACCGGCAGTTATGTCGGTACACCGGGCAGCATGGCANACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCNGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCT
+
9(/<79C@G<"):6,17,FC3,D;'03"EA">(*?"/B,B0A.#B+H<"C8'<%@5E>F--&(D,D=<D32@H4-/CE;>*3%4FA"%A6!5/:CH2>)&=/'5/B;:(=7*HE*.<4"F?65@-6.:7H2E#>G@.540:0%)58H5908A5!3*)=9".8(,76$E23;H0-G83F/C6H49=D0=3-,BC<*10"14<DEB*")!,3,E'/",3H6/6EH@D$C>D/F"$99#BH!?8,&?5>--F+!:&!2.
@r566
AAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAA
+
<?!:!F#<B??D:+<..-6#C>8"4533(E90;FA*(D.9!D5A4E/?=2@;,*=1C?=@1H"6:@@21EGHC6,B8
@r567
ACTAATGAATTCAGGACAGNCAGTGGCNACGGCTCAGTTTNG
+
A!(<)<@::B?2C"*A:<7>2<B"<,.:66B4*7-%$,'</G
@r568
GTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAG
+
00H8#E?D25>G#@73'>CG778=8&,.$@+=#-(0+CA;@?/F
@r569
CCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGNAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGG
+
2&B3?;5,,90=+-9#D>/8)$=!E?!4?/9*D+B63-5*<D+D,)E$,67D'9:1<*47'2(,B2)F1-:+96>(!0D$>65E!0F?8(5GG42A#>?'C->3HB70"&!/8).:.@<,%BH-D,AA829B0AHG50B/-$>8(A1%A.(9#)$C3(
@r570
GAAACTGCCCTCCAAATCCGCNGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGA
+
?+H.C@4G/3(B7<)1E'8"=?900$@(52<9%B#'2$>&%5B;-'-A7$.9"?0C3);'&)?'$#591DF42F9$6$'D
@r571
TGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGA
+
?@!F:G+(4'(25ECA)/=5$06%A>5*(GB7/FF.78'9D/";
@r572
AAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCNGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGNAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCNG
+
,%3('*E+?:!#G.CF&%0;#@+692A4"(/+?%H#&8A@*@6,.#2;EF>0D;$2746,"1:E-F'>E/;:0&3*"4D&@96!(@6?#?57F"GA78><BD1#:H'5+$3*&%@:.;$'=4$#<85>222.H=E.G6<)1%"?#*FBE0D@+497H@7%-F41DE>G2FA
@r573
AACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGACCAGCCGCTGGCG
+
HE>%2F1#,"6':4%49:*"<%6/A?)%!D!:F9@,"7:%-CB:8.D71*$,'DG:-5'
@r574
ACATCATTACCGGAAANAGANNCCGAACTTGTGGCCCGTGGTNAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTA
+
)!&'(*&'&*'("*&("**''")$#'&&(&*+'$!*##$"$'&%'&$%'"##+($)$#)'+##(&&(*%&&)$*&'+"'+&*!'"())$($)&+&+)+&)$#$&')""$+*'*$'"#
@r575
GATGGCGGAAGTTGTCATCNNTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCNG
+
??GB<A,=%+$,,!G**#.H)@E;""43)E0D?'"?.@+;C/A&9DC,6?<7(E4*)@.2BH)H:
@r576
CAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGC
+
3F!/C0.%'"*-@$-G>4%$4+1-#">:9#G2F?%!H8@<;$;?G+@;3DH<<?&=?#DA645C@
@r577
TCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAAC
+
F4DH5!;<3280@"'"$F5?:+8=696)&6+:H$:F5H''9D!'&/62*/6@>8>/C7=A??8&?*9?+6@0-=(B#>-.-+<?H8E=>GAG=#A2&>F5*&)G&.:>%(8$H%B
@r578
AGATAAAGCCAANGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCNTAATTTTCTGGCGTCCACTGCATGTTATGC
+
BHD/#6?6-$0.4>=EECA3H%+(*'?99?FF5:+:&-HE/;3%0B9:#C,E,A-#;>D*-:DB)40@@'?)6.*:!H*'B"9(B
@r579
AACNGNATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGNTGACTGCTGCAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCNGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCNTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACANGAAGAACTTGCCGCTGCCCGTGCGGAACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGNCATGNCATCGCTGCGCGAATATGCCGGTTATNACGGCGGTGGCAGCGGATTTGGAGGTCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTNGCAATGCCCGCGCAGACGATCNGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCTTGCACGCCNTTAA
+
#%%!%!*+'"#$*$)'%""*#)+%*!*$&'+'&&'%"$"*)%#+('*%*!&$%)"+$!"%+'!%!&+"!'*"&"$%*"+(*%!*#$!%%&'($+))**"##%+!!!'#"%$+#*+#&')%%$'*"!#!')&+(#&$)(!&)'#&""+(+"#"!!'+"')&)())%$%**#"!*%*"$%')&*'*'('"%'*!+"$()$'))!+("!*#&##$&#))+!!($)'**'$+(&*("*')"*%$%*+#)%')*!"$!"$"&(*#&'+&!(+%'!!"'!*+($))#&&#$&$!#$$*')+(+''*'"*(*"'#!$+"#(*"#!''!%!&&*)*+')(#"#+)(*%)+'")*+**%+*)!!+'")$%$""#(!*(&!))"#$+'##&)+)"(#)*+&+$*#+%*#!%++#%&$("%&#'"$++)#(%+%$"'#!!%'"**#)$$&+*#*)**'#')%%#*+!&"'(""#!)(%"!%'*#+%&+!"(()'+(&#$!+*"+%+(!*&$()+%$%#""+#**%#$#*&&+!)!+%)#&&'))(!(!%%$#"+$))*$)&&#((++$*"%)"$+#&&&)++&$*"$"+#&$$*%'"%#*&)##*)!##$""&&$&)#*#)$+*!))$(+&#"#"(+%&#&+$%%'#)'+*!$+"%'($)*&*+(#'()%'""*#"+$#$'&()''()%"!+$#)%&+&+&)'%!")"(#%!)&"&"&$#(&"!(!$'*&*(&%"$(($"*('''*+$%+!)""$(&#"$#''$+&$%+%#&!#!&*+'*)!))#&&$+%"+'+*'%!*(')%""'#!%#%*)%&%!$'%'$)($*(+'%+")'&)""&%&&)+))!+*(%#$"'!*%$)#("&+!*!'"(+!%'!&$+*&*"))'*!)&''+$"#+&()"*$+$&"$!&!%'(%"+)&!)$%!*!#+"$+!*)!(*%"'%$+(#*
@r580
GACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGC
+
/$@.F@-/4$:%<:?'?5-6C+/";++*5:97A)8@4+/G.C,+GG>
@r581
AGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGT
+
20!:$=*&">/4BC6+-+HG+*='@)()</70#6?9.C$"?!=F!<BB$982H%GB8HE
@r582
NTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTNTTCACGATTATCGACTCAATGCTCTTACCTGTTNTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGNTCTAACTA
+
#'+&"'*#$))#('&&&'*(!+#)'#(*'"!(#))%!'(")'+)$"#%*)#*$***%*"**"&&+(%%))"'#**()$($!)(&*(&+!#%$+!!($(+'$&'!)+&(!!'#"(!&''#+#+!"&#()#)++!'"%''+'+%+#''!&+**%!+)!(#*&+())"+)$)$'$&)*(+$$#"&(+%"*"'#%#'+&#%(")(!&&%*$&!*"%&$"#%)$#"##+'$'(''
@r583
GTTTATNACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATA
+
BF$"49".&,@/<ED!;FG99B:G$'#</*&70H(;,6GE2+G)-?-&6.DC89%:D6,.?1-1F$GE3'84:2A/14
@r584
AAAATGCAAGAGCAAAGACGAAAACATNCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAG
+
A=4;*%>#"5(89:G"G"<H38+6D1+.2;<1'&68F7C(5@BE,E==,9')01-(=(,H(=@+E34?!879."/;8E:GH5FFC7%+6:D-%"
@r585
TTCAGCAGCTACAGTCAGAATTTATTGAAGCAACTCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCANTGCCTAGCAATCTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGNAAGA
+
72350)0@00G<@F9F(16D(5(!-9+G6;F3.,"EF>H8$*FE48.;&7@E"$+-!76(')9A7;.%&)CH&=AGD5%1(;(H-63)(&!56B*H+7#/@=23@@+21#7A82%&@6C*'D>1H('<E+H%<E*:>DC$G/="1=(#
@r586
GAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTNGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTT
+
%AF6D8(49;G+<C$H&F<4:)1;,&+&6!C#'<67="DAD87AFA@;B97F44,*'B=9>+D6!771F=:+@45>H53&4#/G3@'HG01)GFE6$A>=#C8.HC>3)E71G&,@'444G0-H*=)5=7'.EC#;@
@r587
GTAANTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCC
+
'%$%#++&$$))+"+""''*)))!+!*$!$%"#%+"%$!$!#"*
@r588
GCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTAT
+
&/A/77.FH+"/(/C.&<&.6D%CB:1$.G9-,GD=8E4%*A*@1#%=?!,4D@"-EA-/#0:*?$$E:8"F4,E!=>+F>
@r589
TGGCGGTGATAATGNTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAG
+
*@"F"4')FEA(E12%+5'G4";&&#7B-590@<?E910)('E7&*4,;DB*:':HF=E6#;&:3-.B?C(E',:!.=%(7*;+>H.3?;;%*3@'"?/?"4B,D#8)'(>&%8*39+08&4C,C:6*1/.<D94<)H%7$%!6:82*A/B"3'1"!A+'C#$/8"#G%A(&$82%$501:.D:.8G.&7/)0D!<0##
@r590
ACAANCTGCACGGACAGGCCGGTATATGCCGACACCNTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGNTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGNCTTCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGAC
+
D@'EGB)841*B$'2-$."9D@36+8.C-6C?A=6E0?/:AE292"BH:9)"<D%&6482;H*0"EE@(==-?).29<&!$2$920,,(=B#:.),HD+H-97D$211<$'5C<*)>>&8?6>H17B;>-C)(72%!8)5$=#EB+2.F:4,<B?;B:->?"!H<3;E%%4,@-D8A.C=$5.)G2F!@?")9!:'-%C1=@>5F4-5(@'66>2*?:AF'#!17#+.)%=$A*6"*#;@D<*7-
@r591
CTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGA
+
<%14<7&!EF'02-7D@27>0)97)<A*(,%"H-;+1:.:F9HA&7
@r592
GCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGA
+
?B'83E!G;?>1@7G?9A#?<$,>)@A*:.%7<H:4G3#/:6=A"6D8$&A)E/0F1-,*
@r593
TCAGTGNTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTG
+
DG/1:=80<:6#2.8?07-;3G>+E%=H.*!'1(!6!1#:B>G/(H;@<5>B"4*/;#
@r594
AGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTT
+
*,02/-GE*(:H@8!F/&!8E/4?C4:/'3!@)79!'/.>*E,4:AG%$:070%!/8#$A:
@r595
NCTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCNTTTGCCTCGCTATACATNTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCA
+
!(8#*&C(49)C:7B'++B9.8'515,,F!$G"C.+AD,'H?@"*6+5"><#8#348C-<!83A+'DCE:8<$C@2-:CA!A&$F&$"@EED5;H;=4:1<13D$=G6CB"4<(D7C"E!#=/69>/<A6H;7
@r596
GATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTAT
+
H;%-H0A+%@0:5>,H<H7?%+E:AG3<#4$#-7GD'*8<9(?A*=*=#3?;/#)/96?-'72;G,)-:?;=2;/*D)9@:-B"
@r597
CCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCT
+
B-/?7B#*&8G<>(:';*2B)?(9@@/;+C"7#*1(2@.*"*@
@r598
AGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTC
+
:G<@/9)4A52=>"B52%+-7+)D%&$92HE8BG+DE=3G6)/*7#->10D(.D?8C#E3;&7CBB$CHC.!*"#:@59E45()(C
@r599
GATGTGGATAAATGGGCGCTGTATGTCATCNGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGT
+
8)AC?D(A.>,.?G=./)2DB9->$:5$3,5/&A$)8=E&2#-"15@-")"G&D-,&)&+EH;$(&0B(:/F16B8&9/!3G-+&5B$)!?#>'HB#*A3<213BA1<!-$+!>:150/2%)%0?&.1C?1,7&=0($,%*?:9;0H@!A&8G.%32$'B1157&..,?:2!*>)"F7"9*"$3.<8#8>*CA
@r600
AGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCANGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATNAAGGTTTATAAGTCTAATGNAGACAAATCCCCATTCTGCAATGTGCGAGAAATGANTGATACCGTGCAANATTATTATCACGAGTACGTTGGA
+
12AH9374.CCC2#;HCG+=1$&5=:GEG/4B4C@:,,*AF?-:0CGA%2@2)D,9,8>%G<F<*&8$/8:+*GH09@#&B-:6A@!9/64=)>A?G#9/;GB;G,;@.%0;=<%7$)(=E19=$")783&D2&$G%%&?'E:!*$H3)?F4GD=H0E?HB.)7@H-;1>F<7*?&EB!?F;!H(!)#6+C,,$-?D2<-+#!7B4>,
@r601
CCTGTATCAGNACATGCGGGCCAATGCGCTTACTGANGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGCACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCNAAGATCGCAGAANTCAAAGCTA
+
?+):/;>2C.367(>@"=&@:<2AH!@8D.<,D8*;G6;E!+<H##*3($816,<"644%=-D>GC>)6#*HB!,H@BE;3,5G4-0GH9!#G78!19&%";:H/GD4;@B#22+-4A;5HH#5>E39536892CE+D"CA=C="2A@:12-.'3.&@G7%%73/='8,(1>*(&;@,80E;A8/'"448!+&,&A7
@r602
CGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAG
+
E&>?830%&%3/C7F<A3'>$6>;=1!&0?&(7G5*800:;-?<9H17=*<"63*.,7@9<)0C/F->$:&@:(.%.05$&(
@r603
TNNCCTGGACNAGGTNATNCTAGAAAAGCGTTATGAAAATAATCTCNGAGATAAAAACAAACNCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGG
+
%%"$')&#"$'))'(()$(#+"$')+()#*!(%')$%"+&!&'$!$&''"+)&%%##)"&$%#%""$&*')+*&)+!("'&)'&+)!)#$)''#"#'$!"**#"'!*%#%"%+#&#(!)!!)$
@r604
TTCTGCTGGATATGCACTTTNCCGGGCTGANGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACNGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTG
+
5BGBE+:*'FC&)4%>G:*)(=6-5G4:!#&+!CEF,1<>=.A.2'D8C7C:*@>4;C,5:$(:3HF!5'FA$7)(!CB8%2AEE2H$8#$-%>FHA(C4/.!,)!/$-?@EE%)8C;))9H(B'F<?!*@0.>*2+@;>,9*!=!>0E@7'-(#AD+(:=D1C"GC$H!0:1+.88/<1#DD6*&+2F)-8%.08EGB5=@<0(&>0B#@)G)(8G<:32D)B6;)+:GE<!F&$6?>D4?0,5@))5E5-E?1""-/:E>'A8/?>13)=0'2.=.)-$72:D!=,!"E@
@r605
GCNNCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACANGCCGGATTCGGTATGTCTGCATTCTGCGGTATGCANGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAANACCGTGNCGTGGCAAAGCTTGAAGGAAATACTAAGGAAAAGGTACCGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTNGTGCCGCGACGCCGGGGGCNAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGANCTGTGGGGGAGAGTTG
+
*'&&+%%%**$+&"(!&&"$)&!&'")()%!#%)''%("*#+$()*+('&&"($+*#!'(&&####%"%#&)"'&&#*&#"$(#()!!&*)"$*)&&)%(%+*+$)%'*!(')*"&')!%&++"%*$*$&$&!"#%%%$*$%"!!"$&*&+*%)$$!"*))()"()(***)'$''+'"(%%#!%!+*%&"&+$!&%%')#%''%#)$""%$()%$+%$$!&""$**&"(*")+#'+!)!)#%$*&#%+%+)($("*#"*#"($!!!#'#*!''+&$(+)%'"#+"*$%+)*$'+&##+#$'&&$$%&)*!*))!$($*+$"('(!)$*'!))!$'$(##'((#%)'
@r606
GCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGA
+
/2D#>6B13),4>86<8))C+5D!G<,H!$<C'"&4#&32@,0<HA"3A4"%)."D.8=."FD-%G514)1H4E=G??"F8-98'/>D$-'196<%0
@r607
GGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATG
+
177@5<&=-"/8F-9"?,A67!)+*!#H'596:HG7C075,?'1E!
@r608
TAACGGTGGCTGGGTGACGGAAAAAGACACCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGNTGATGGGTAACCTGCCGCCGCGCCCNTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCNGAGCACTTCGGCAGCCAGCAGGTGAGCCGTAATTAT
+
&:$1@):(81-HG$G.DF+>'-6;8#,'))<(*D3DG!"HB%-H>;A,')-%5<E;*41(->"64E>,2!"8"F#?",'-4:-,@<241?C'@.874EH89$)18=6>CD190#?=-4<>2%+59-A.&53$$.A"%H4+8/;(H.1%8+85)C7&@/;<D91?1C+(-:G4B>0"2)>7-E/+'0CH"6G$%-)7!:!570'5H1-GA-9##'H+%0>=#!,4F+D"(?.DB"FD0"D-6F&)$.B(>$?&,'8')F#;1B14!9:#3;9.9F39?)$2
@r609
NCNCNNTNGTCAGNGCGATGTTATTGAAATCTGCGATGATGACT
+
"$'$#*#!"%#!&+#+*)&+!+("'!&+)$)#&$$"%&!"!#%$
@r610
CTCTTTTCCAATAATTGGGGAAGACATTCAAATCTATAATAGGTTTCAGATTTGCNTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACNATATTTC
+
7"34)-1A*E2>').-E,1)F;'*CB"CHB*'*+:,0(:.<:0"$!!(G0A<00#)C0"$1.D%'7@($9>F.4'G7&B,+,@>-+$%8"8"ECF3#-04!97#-@)
@r611
GTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATC
+
A7?5G6:-=/3#$@!2)98F1&.-#:2=@H.4/;'*F<:%%!&&:3@?7%',2912+C)(&9&14G03&5?93;$@'('?#@0+9=1*!,9!
@r612
TCAGGAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCAT
+
35?;&#A$2-&3!';#!,(:A1E27G5A"#$FA"2CC,C02<3&,0'>'H;1;*C564?4D2*<451H/50892*,,"1,;=7:=4G:>504C>2A+4+?C0!E"?%)@?F)G646BE>%4CA5983
@r613
TCATGCAGAACATGCNTGACGAAGAGCNGGCCATTGCTCAGGT
+
+1-,1F9>0-=*#*(&1@)6:>45D69?>*!)@)63;9&,+9E
@r614
ATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCC
+
1C9D701H&/&5+;,F3=/D!'0;6.3/?B*1:AGF*$<;%#%;3#--7*E53**5HE:D7H>H@-%
@r615
GCAGCCGTTCGTAAGCCTTCTGCGCNTCTTCGGTATATTTCA
+
-"&D/@#>'3D/-<5H:5DF7<:C98,)0;?C3@#9<1.,"D
@r616
ATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCC
+
9F')'.831D:.C43E9-6>%*7(#9G5:G*5DF*B;$08H$@9<%97@E99
@r617
AACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAANTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAG
+
%/8F($<40-29)F3BGG$G'C,;.5-$)7.A&.%@3"=/'50=7H9A:<G?D7**.1447@&?,2+/AGA=F,:B&D%>'8B@;=@5-?8<C<*4>'!:(;306+"$E9?32A'9@-3B-8F95G-<GH08(D7>@C2B#%.0!.BA213,6'BD"5!+"70B;
@r618
NGGTGAACTGATACCGGGGNTGCTGAGTGAATATATCGAAAAGTCAGGTTAACAGGCTGCGGCATTNTNTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGNGGATGCTAATTACTATCTCC
+
'%$+'$)(+#+#"&$!'&$!&'$'&%'"!"+"'%#+!)&*("(+"&"%'&#&+)+'#*&"$%'(!)'&)%"$&&$(!($!#()#"%*++$()&$(&!#)")!#)%'##*&%+'*!'"+!($#%*($*$')+$&+##)'(&")&!%!+
@r619
GAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCGGGAGA
+
'&4'86C#D4/20GG4A8584@D)/8240#?$+%",*6C=5!EBD/*!A@%%C5>:&#78447$3)1'.!"F"CD%&F77B5>#;:!>),;%B4A?6*>$05=5
@r620
TATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATA
+
6/GA7A63"81<'H"9D1!!E"@"%2$1!(..0,@GD<4DF+4(/%-(C<%5828,$H("@C&?9D@F=E)G$-G9%/AB>#1&3#1543*-#3#*9$.,"3&A,90%%:-63=+-3>@-:7=/(9)#!G0?+7H*
@r621
GGCCTTTAGTGATGAAGGGTAAAGGNTGCTGATTGCCNTTCCGGCAAAC
+
69%E(<$?316?G@4G94B$8F-H7+:<%=4.&<%-#%H+F2,9#*/GH
@r622
TNCGTNNGGNNNNCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGNGCTGGTTATGGTCAGTTCAAGCATA
+
(&%**&$#'&#(#+!#*!&%")%&*$)!#&%**)"+'**#'(&&%'#*&!##)(+#&%!$(*#+$("'"'$$)"%
@r623
CAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAA
+
-(BHD/!"5/A9F<D-,2%0+3F#90'#@'?:@-6!74#5*,3!*9A%905
@r624
GATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAATCTGCCGGTCAATNAGCCAGCTTTCCTCACCCGGCCCCCAT
+
->3',=!'>H78@E?0'G+#;())F$)H"7GA#6@$-H(/F.83"98@>9)?F30=8CE(>!E";+#)$-'#D**6>G(0/?67A60-)*7(61+:'9CC&9(4(AEA.?H(2#"/E8B3":+16%<+5E()1+@H&.95"
@r625
ATTATGCGGAACAGAATCATNCCTGGNGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATATCCTTTTCCGCCACTACATTCCTGGTGNTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAANCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGNATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCT
+
D@8(9C"91>9"4-FBA?!!&E<BBH(+D841-8!"&:>39.35B.4%37D-$B@%=D1,8.1*.;16!5G74$HB82/5;"+0%0-+2+?,C+E@-#C?=:.,/2)3=16A'7&..*==H>"$F'<:>6,&<,)%&B<(.!449/"%;429H94F97B,,-4BD352F$)A7!<.,?5EDB10#C;+G%'7;8B2;H).1)-G$@4'B>CFAC0-5!!84B+*H:3:+?*D>692$5F&B$27?,@"65>38D8>"B0*44F)4,H7%4C#,%&D*.7#$@9-+&+@?1#+*8E/+4/#'*A8
@r626
CTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATG
+
-;,+F<&;>$#>%"="2C:>+9!?47';?,C49@$<(94;>11.6@':
@r627
CAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACANAGTAGCCTGGATTTGTTCTATCAGTAATCGACCNTATTCCTAATTAAATAGAGCAAAACCCCTTATTGGGGGTAAG
+
"(=<2(2:#9BA!00#E$B../F<,4B911G4"D(B$!1FA)>F-,9-1@>:)";(=EA.;E0")#%A<"E5"B"?&3445)1(<,99C?7:A+$7"<-4@9;F)19C,58E=+'D=:#&@80(H/;#2@!'+3,
@r628
GATGCAAAACGATAAAGTGCGATCNGTAATTCAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTG
+
>8!EC'FH.A<HF+68<0H>0&"#A+!5#7/(C+',BB<H#)F1>5E+$="(9&4AH,-*D>B;=%4')6016>:,"1:%H=:3-(>;!.+>226;/F./-G/B".C*"4-2/+.%&?#D"6"-)+G*+HC#663F9*(<';"<#9(0H>(188&&C5B#CG,,A5G14"G1=2")?(#*/6@4.1(6-E3F?$&6'45=
@r629
TACGGATAACGGCTACTCCGTGTTTGAGCAGTNACTGCTGCGGTATATCGCTNCCGGGCTGGGTGTCTC
+
2-)!-8686$#78+BE2;F%:A856$FC9,@94@?:G;2#)";;@::56%+79.)C1")16D95,.!?'
@r630
GCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCACCCGCTCACTGCCGTCGTCCGCTGTTACNGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGC
+
*>-99-,62?/2D?$D,6<.!'9);)7E1(08*,>/C,'A*,(>/34:45,<>2%D,9/+:;=#-38&,-B"8H5>*:--B<D<A@@@'"%G$3)CD;3F+)0A:/9D7E7/,!>*2;?CB/CD8*D=3?'.D'F2>D"7F+FE13H5%H2+CG",<%>,%B6*&.B.3%(?4<$A5<70+
@r631
TGANAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTNTAGNGAGGCAAAGGCTACTCNTATTTCATCTTACATTG
+
&'%!+*!'&&$!)(()$)#$!##)%+")#$%%+&+""**)'$&&"&%*!$%+(+%#"'+(*+$$&!"'!"%+#$%!#'*!*%"*!%
@r632
TACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCAC
+
<$&%FH%";G.@.).G'+@1'H*<"()!=/36B+*')-E3+G
@r633
TGTGAAGAANATTAAACAAACCCTNAACAATGAGTTGAAATTTCATATTGNTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCGCGGATTAGCTATGT
+
D7=<F4%/#GH+2+"4*"C!G+3@3%192F%'%=/*!'HB%?'!0@$4C2*8A.*9$/6+CH<9D>&1;=5<G6);;D754$BE882%(#*D@>H56@(%D1$H.E9,H#))?
@r634
TGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACNA
+
EFD">@G0A:B/2<%68&!C0.E%BF-A7A;-,$/(94'9E/C#E=#=9+(,73!0*(B9</H"2.-C*"%30:A1FD7%0CC$H.!047)./-F@(*G;.,3'<1:=0)<B)"FG&67C&ED@!-3C?,
@r635
CCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGTAGATGTTATCGACGCGTCACCTGACGCACTGA
+
?'C*E08=*/7>22D"@>!"3<5!(*.3H5(3#BD?DA%+928H3>DA6+@G=:?;?">""<7,>FB:D5F30:&+#%5($:83)C5G868DF7/7*@73#0H5G2E":
@r636
AAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATNATGTCGAT
+
4B0##5EEBE9&F5G>2C3"48-(H?+D&40':"3.<5%:FB6*)?;)"73/7*4/B3>))C<-%2688<+@)+6H/)?=5A(A$*#!,5/1@.A=49.7FH/;6$D8FC=<A?:7<#GA,
@r637
CAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTAAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTNGGGAATGAGTTGCAATTATTGCTACACCAT
+
4/D*=;H4.F)*-/H=>,@E(/H(&-&/<6"*,C8%$,->BG1G(<&!AEC<+;#&1;D5+:39<330@H(;8,9H,GF4G(+@=.;>@8)G$:@1>E-)'.H;)($GG8#G'%@,3,C6298A-8"(&9>77H>%$:CB%E(/-C95;3@):;EC6'C>2,69'A81-,+34/+(!+&;(/*!27'F"+7.4>8)-4!!%H!$C)2B<<<D(
@r638
CAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCNGGCTTTNTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGC
+
9!C5!+<:BBA;8.,!@A,2D=)E0G1?5/!BA?FC7?%#!1=5,,4D;@3>7>#@A=@G5"E+3C?C-=>7-!651@2+!27/B0,0..">3A7G"@0:25.$*'>>4=1H;8"=/@%,?--*%FH98G
@r639
AAAGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAA
+
H48-!0DH<8GGD+A?'#,70D(G&7:C4)+":&>9-#8$!A&@:6='CEG+GH?>2B<*#
@r640
NCGTGTNTTGCNNNNNGTATGAAGATTCACAACCGGGGACGCNGAATGATTTTCTCTGTG
+
#)$&''!"$!'!#(#"%+*$'%'$(%($&$!(*$#%!%(#"##"%&"+!!"$*('+"+$#
@r641
GANNCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGNCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCGAAACCAGTTAACCGCCCTATTCT
+
$*!#&)+$"!)&)%"#!&)#+*)*!%%)!)#+#%""'"%&)"+"$(("$()&'+')+'#*!**#%$+(((&)'"(*%%%&%!)+&!+!*%%$"&"&(!&)*&"+%&&&"+%%+!%%*)&%)
@r642
GTNATGGGCTGTTANTCATTACCGTGATAACGNCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCANATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGA
+
%"*+#!$#!#"+'"!+$!!')*&')*&"!#$#)")#$'$#"$'#+'&$"'+#+*(!&%)+!$++%%#%($%#)*('!#"+*$(%)$)"*&*'#&++!""#$$"%*$!"'(('#)*#%&&$+$)#&#%%%%*&))$(&++!$!)+)'"&'(#$*"""%!+%")$'(
@r643
NAATACCTCCCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGC
+
#'&&%))%!)*+&*($!!$"*!%)$+'#&!*$!"%#!%($"*%''%#((""%+
@r644
AAACATGACCTGTTGGCCGCCATTNTCGCGGCAAAGGAACAAG
+
E*E93A%A/&&"E@04$EE-?@@G$>.B!@6BG=>2;0@E%;<
@r645
CCTGCCTTTTAAAACATTCCAGTATATCACTNTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGAT
+
6:;2(1&5D)B/2B>-+!2G-G$=<G5)@=34!,31A@!:$G-HG>$-!36DB%*.;F*E>74B."/$D/@!.H&7$G+%20=:F*>&=/B=5,,294A<CA,A*34:
@r646
AANTTNAACTTNTCNAAAGACGTTNCTATAAGATGCGTGTNTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTT
+
"*")'#(&)!*$($!!%"#&$''%!+*%")'*)*$+++$+&%#$"#$)(&%!"!+"')*&#"$(&(++!&$&%(*!!%%!
@r647
NNTCGANNNCGNANNNNGCNNTNATNAACACNCNNCTNANATTNGANCNCNCNNNCA
+
$"#$$!!"$!$!"!!!!$$$$##""$!$!""#!!!!#"#####"$$!!!$!"!!""$
@r648
NTTTTGTGGTGATATAGGACAGNCAAAAAATATAGATCATNTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGNT
+
#'+'+##*)%"*&&$)(*(*%#$)+#'&#)"!++$$#%(+*$*%"&*!&+#!"#!+#&*+$(%)&&''%$"%%)"!!*!$$#"+$"!&!)!)!&
@r649
GCAGGTTGGCTCCAATTATTTGTATATTCATAAAGTCGATGGAAAAA
+
&-6.24.&'D=8("0)$H?C"1BC&2/7EG)FA;=(,C3(?:!(GD8
@r650
GGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTG
+
>E986%"9G335"BB-H87#G8,/C:D>5)A'+?H1,+<'=A)&="""A-?-7(1HH6/"DCB99<#2FD!;2$5G682.
@r651
CCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTNGATGCA
+
3#!/80G,'E"#,$$.8?@3&+=8+>E6=&@4EE-F%/&D3;D'%->$(.=88/'5:1+"'>H(>+C#B=.7!(4)-
@r652
CAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTT
+
/3E/8:&/!4@'$6C5+9#-.'3>7E!/A4')+():;9"2+)*)322);@D35
@r653
CTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAANTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGA
+
3%B)0/!<&427F)3B0=9<(6D'94>C8E="7&D1H-$EC7$0)(3(0$*3#);%F7A3F80$G"E#0F<,B"C(C0=,"*=,,060@!0$!C(??76=327F8HFE;-HD-E<*$H0@HDB,/#.!@/4;07=/D-=,>2D(&>)$H3<9G,:E&.6A:$1F=4F<;"46)E447=?@"2?G#+B:/3D-&:).+)07FE+&<3!%,+227$FBC.531=&
@r654
TCAGGGCTGTGGACATAGTTAATCCGGGAATACAAGGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCAACTCATT
+
@6$>66=8%=-7='/++11E7-'2!<'6C+,A"2;D7G-*-@/0F"@F?:<BHFFB$)H,4;%?BE*.(/?5!=3!B<'-0<+);%+B?B12&6/=)
@r655
TTGGGCTAAAAATTCTCGCAATACGATAGAAAANCANGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGNAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACNTGCACAAAA
+
@C07,?8885<@33/8*$=1G&#:F5FC9AB/0!#"-D$!</9>')#9B59$C")+?E;'-0H#+=A!'<;;D;.?5-('75=,7H@-=+DC4<*-4=%C!"=,8@46&FF?<%697!E6.21)++%-HDD5(@D=!H5C=";":-$@G?&6.+72+674"C7#2=.%02F
@r656
GGTACATAATCTCCNTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTT
+
:3'A>'1D)>..,%3@G>+<;$H':!B(+!6#F49!3*51=H(H2&5=:)"5281>25D45/B0<@.;,>9:83>0$=1AF:0+8!&HHE8E*$9%,
@r657
NGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACNGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGNCAGCCGGACGCGGGCGCAGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGGCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCAT
+
1AG;C682-DH3F@(#82E:$$"@C%!,?D@:'(53*)/#+/<.%A@1<-B;E/B"20/.32'@<F-<F@5:@@$=%FC61>?EDC)<,1"%DC$$+06*G$440*0>E/%-&48#006?,1,A)477GA>B&!,*G:D,,@AF*"!$'25-D<3$?B%()>.,;<3#"C1DC&76(%'2B'74%=&(9BA9<$;/4C&15+0B4D7D#GB-)7D;G;C?-B@72(3EC5&>@D4(,.;DD"=%$/63>G'=!E%F7CG/39(@4FB$(:!G(5$HF"#?C1!4@G)*G(/D;+&B5)%?E;9*:25AHA(@;)49-0;F=)AA:<-->3B"=A+>A4$D)4)$=<&4@)4+9<%11HA5HBA..61*H+;/?),6$B/9'E?<%63-<3%B</>/G<:%$55/+3.+F62
@r658
GAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGA
+
C9#?1/B;'6=/6>DC6$;:1G:<@.G&%/>$479FEHC*5G<5G0+'.:2EBE
@r659
ACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGNGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCT
+
F'4%!G!6&7.-1A95A!FH?G"H4;)2E8*;D-77>68C*F+B(E>1A4*B%C$F@:4+(CD0+/,:97DD798+4'-.":>#;=4?4(<CF"C
@r660
NCNTANNGANGCGNCNNNAACGAAGNCGGANGGGNTCACCCCCNCNCTNNAAGNCNCNNCNCNGGGNTNTNCNTCNNGGNNNCNCGCNNGNNGCNAANAGNAAGANNTNCCTNNCATNAAGGTNGNNGNCNACCGTTNCTNCGNCGTNACNNNGAGGCGNN
+
!!"##$$#!!!!"#"!!#"$$$"#$!#$"$!$!$"$#$#"#"$"""$$##$###"!"#"$$$"$##"#"$"$"$"$""$$!$"!!"!$!$"!#$$$$#$$!###$!"!#"#!$!#$$#$"$"#!#""##"$$$#$#""#$""#"!"$!"#!"!$""#!#!#
@r661
NGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCAAGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAA
+
,BH'1;64>=3*"@.(66F+0,+D9:H-(=5C.7,15B4<A=G0:<:A&&4.+4F"!B>09G%G499/.)*F<,G(()BBB6=/8>>*,+73:4)0=>A15+F,=5&40;<B=&EHF%57:%:(<9>;,*674-;"<DB79+GG,@"5;8)0C5"-0D'1G)(*F+<;13831#8%0;0CH52/--:#82+F#<H%$)%0=)B28.<BAE>7+@600,
@r662
CTTTATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGGATANAACATAAGGTGTCTCTGGAAGCATTCAGAG
+
&;:10H*B%2AA;B@(%D72%28(0;3)6!!/499-*=("=4)#H>4B&:(.-3C->@A:>C@!(.:G:8-.-.9F;44D1C
@r663
NTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATAT
+
'C1@+%GF*0-/8C3<@E40+6FH77AA4.5E@?;5;F(%/F2@003#%:&>%BG?H/0)<=@E"*#1*60D4.=,
@r664
NAANACATNAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCA
+
#'($(")($&&((+&"&$*##*'($$(!*+#&*''&&"%$%"$(("$%'""%)$)#+(!%)(&$!#('#$(&)(&'$($(&"#%!%$'$#$*"%)"$)+%""()((%(+"
@r665
CTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAA
+
*8!$@F')G-BG@=HB$1A"GC;?7F'C#:C7!3F:E79&-<
@r666
CGCGTATGGGGNTGGGGGCCGGGTGAGGAAAGNTGGCTGAT
+
:?GF""-758@($5;H;D.>'0:5H0;(&&67E8>#.E.8#
@r667
GANCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTAGTGGTGATT
+
$$#+(&)$"!''$&+##"&$'(*$$+*(!!##(+*+((!#!(*()%
@r668
GTCCACGTCTTATCCGACGGTCNGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACA
+
3.6:!--3:>!!B3%<,C.7;B6.F7DF23"2+(%!*(</+;D?!CC6%2%-E.*$7H<,0B7#3EF"
@r669
GNGGCNNCNNNNNNNNNNTGNCANAGGNGNNCGTAATANNNNNANNNGNANNNCNNANCCNN
+
"#!$$!$#!"$$!"!#$!$"$!#$###!$"#!"#$$$$!$"#!""$$!""!$!!$!#$#$!!
@r670
GCAANCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGC
+
(-:!1'1-!50'6H%84H-#D&*F4A!6B;.!>AB5,.&=5>+)02B<,F65$H254A
@r671
GGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAGTCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCNTTTTACGTTTCTCGTTCAGCTT
+
%5(HD<>F64&.=D8)2GFA2G85D*AGD:((9"):>+'+3,@3B*B)/:8.0D@4C%%)B,+B:BBAB+C@H3+76,G5<>;%#09,A(B=9,=1E3?<$//=1798#4,BC1AE?(4+7=;<>:D)997>95AC19#'>94.'#@42)@?$9:"&<69BD'#F+6%>"+&>*5D1C2%H6)G##(("AF0FE?=C.8&G
@r672
ATCGCTGATTCNGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGC
+
F3,GB?+E'%GA>+?)7<H&G0)?"/+<5&&,%#/&&-%.)B5,A48-2!D5>GHE()?":12",/&B@8,*
@r673
CATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATNG
+
C&&);<1&0=A:;=-4G)F+<"6G&(-?;$F2('12A&*GG5A-G&A)7(//:
@r674
ATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACNGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTG
+
17;F"/37-$==<D77233;D5</E;A2&5%>'-@BG>13/(/F4,(.9?1&6$><,,%---117-?)C54#;;!!-->$F1,B/CBG(&(#<3G?-B8F%*CG-8%=2#6B5C@GH4!,2E82C?C?A"?"B4?022"$G?&7(
@r675
CAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCANAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCG
+
/;:A(7!=;.!@@9G=0321@:-$2>%2#94A4%<GH0F!0F315!+A=/0-><5DG?;"1+'+0/F71F.)DAE)B%'7+&5(D,6E;F&>H7:
@r676
GCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTNATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTC
+
4;H9@336C1@6G%4=H6E!@91!F48!G@!>*G5#DH74D!;-=!+8),):*4(BD8$%<4,"80A(;'<-@)"A*6>35(70806<#5$F:1,E.
@r677
ATGACACCGGGGCGACGTTTTTTGATGGTCGCCCTGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATAC
+
H%?8;6;*#<F"AH&,$G8?$1G2D!F.H1+,/3B?)2(%86C/G1,@*5-=.D116.-*EH9G:$!:G0HB88+,$891;7"'E#9A"?/52F;6>>D@:+?949&"C'$DH,G.+(GEF
@r678
TGGCGGGTTTCCCCTTGATTGNCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAT
+
A("(3,%903".2,8/868EA/,;78*FE"#E;A>>->"F1-$(.=G&5'?3A+6G16"=92GE$>//53!6H1-AD(6)?2A+)-/?*&$A;G$-HAG>@"&"E!8,$"!1,0>E;,<2D11BD24B82/75;CBB>#*0727F864H3*8;D..25@H$&%=5,$(G0@15@0)<!#-(&*63E"<%!C"=/%/2*?$4<%3
@r679
TTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTN
+
..A>>:.+139,HB")--H!%'H*7H8::H0)'F&E+6)F@$-/)<?@:@?AC8$5D/E2-86(*%0E%$BC;B=@<8.0E;/0.:&?2?3+0DB1./&2FH%.EDE&0=&AF/"04&422*5"%3F"5),"4?"BB=9'D1"*.>D=!(DH&:)43E
@r680
NGCCGACGCTGCGCCAGCGACTGTTCCGCTGCNTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTCCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGC
+
$F"2);H'+=2E+G78"7//?8$)A:@&:9C9;*F.72,53*(6:!/G'&??(&7=G0&A<&3<4G(,456$#;1/@)(%$-!(B;13'!==EA9H;="7;D-(?"?/<60=6/D29G0:)G(2A4;E7+>@H&=*8-B<7'B'DC<)(&7-'-/BE$&<)&+7$
@r681
GCCTCGGTGGTGATGGGTANCCTGCCGCCGCGCCCGTTTAATACCCGGATGCGCNNGATGACGCNGGANAGCACCACAGACCAGCTGCAGAACAAAACGCT
+
AC*C$'<0%F#&6A.62"-*!.)%./#2G-F3+!2$H7?-$*B>:D11>*-204>"A61C$B"G*B>@+$2D*C:%;<'F%'2!F7@?+%E$8.15+9;)8
@r682
GTTCAGTNTTAAAAGCANTTGGCGNTGATGTAAACACTATGAACAATTGAGTCATAGAACTTCCTTTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTA
+
)0*3$C0-,,<09@)E$*;':&$H>7=#B--+G.@&CB%;)H6(:AB--+<"0G./&E?8;8H)0*8@*!8?68C)6;95=(#&A6/,61."@/1(>,(D?$E!+??.34'0F/
@r683
ACATGAATAACAGTGGGTTATNCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTACAATACGNTGCCCNGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATATAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCNGTTATTTNAATAAAATTAAGGGTTACTATATGTTGGAGTTTCGTGTTATTGAAAGNGGCGGGTANATTCCTNCAGTAGAAAAAAAT
+
5./C6(780&$G)3EB'=(HAGHG15F?'1%=27(A<)"$<)-??,>7:#%D6455:C/@0(5,B342'$8)$FB+?)E-29#>:;,/"+F$D,,"4$"55'8:238F%F-&",:)5H7$CGF#G6*"))*/%$%/16'2!&F,3';$&//%)88%C*FGEB9&2?C2(H!?EG)A*G,>C0"D5.?HA2(,2H<.C&C8/D7C,/"-@'/>8/("HE/='&:8@'GA$83&01"%<$8C1$5<$0E&)9
@r684
NTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCG
+
.F(F.$!-E5C"+)A)%51@9@/<8H;),@<<76=?)E?'F3-)/4>H'@G%<C
@r685
TTGAATGGCTCTCCATTCCATTCTCCTGTGACNCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGTGTGCGAGGATTGTTATG
+
C0'6B<(<FF&#8$?=D'4F7#<+G-;=+3G5@"703@>9FA*B9.$#E#'>8<9EE:<DDE>3AD/E@106?>+E7>./%H&FC&7.7*#$B:+:.&.A28*@6.D&4@A(#D@HHA14)
@r686
NGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTTGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGAT
+
!2AA034?)<7+5;3%FG=159051E;$<<844--4C*/8"+8@9+H7A$=):@,8+3/+4?08&1-;B6<07;$78#@504C"/8/;<
@r687
ATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGC
+
.,-178'%F-55A#&9"B"%/(?HEE>A7:2//E1"EC?-33.
@r688
AGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACNCTGCAGAACGTCAGCCGGAACG
+
H'#+(*:;3;B1(/$@5?)?B8.+"5H#BB6;?&D<+%5:*.&!9==)<2CBA<:+"'8:"
@r689
NTTTGTTCAGAACGCTCGGTTGCCGCCGGGCNTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGNCGTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATC
+
&9*6!H0&<);!-D6"#',"&0C8=?,."%7B557(?0F.%HH#?0<)5,?3(4-G>1$?D!(*D3>?8*@#F%@<":G&E$6&56!!(HF+96,(,5/'?-D."=&4>9E44,B$45!.@G;2D**#C,;'74>D24;H5%';*G<HDF'>3@02-,'+C,
@r690
ATGTGTTCTGCCATGCGCTCCTGAGACCATCNTCNTCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGC
+
E-$=97%5@?-4#1;G)-*)"46H44-<>A8C&3#<!/961',%>?5!4%!8<&*)"8E<CH<=/&B3C$D.*$*
@r691
AATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAANATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAANTTTATCACCTCTAAAATATATCAG
+
4.(%@#.?+)5,=/9G%!3E3(GF<D+-=*6B#8G$#93@2@486+=979*?;";<BH@>"/D;G7%4=1-15!$HA4!11%G.5&,@55&3!=0AA41"=F:-20-.C/?*4)57G?=0"&;C9:?F"($D43)><(BF"(A
@r692
GATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGNTGATGCTAAAG
+
*1')+"E;#,+H=<<"%3;D(5A):.*4D(//</42%:%6,<&;?98)6;02
@r693
TAGATGACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGACATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACCGATAACGGACGTCAGAA
+
B;1.@E>39=E;+?@3/7,D",&9+'%?$G4H9G<*'BD(#;;?"2(A=E190,H.>F&+B1D171#?#3?<(B;,,!(G02.?6+70!6,8D5(D!FB!3=9+)G=EE1%*4=5(5>?3!B;:H4A-'1B-7+E-8%8HE)2*26;'0:(G4<;-&H09=@=/)3-"/B)
@r694
CATAAGCTATNNANACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGT
+
$'!'#$($&$$"*+"!)(#*')##$**#*%(!''&'*"#!&*''++)%)#))*+#(*)')+""$#"#+&"!&#!++#"+"!
@r695
GGCGTTATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGTTAACCTTCCGCATCATNGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCCGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGT
+
$'4!&>:F;.H6$C=/2..2-=*1E&7)5D/!+&,A=&9E!0H7%%:HF7)A5F.A"'@!$.8'!6)%49#8:"&"D,E=D'=96+<&);H2F2*3;0C(GD&GF;)>F8,C:?(-)=(4H6B.6"'&71*3<!G-13G%B@<=#F3='7!%8:,1/3:3591E5C.;8#=??G85HH.;AD,#8>E7H51<D01D.?CE<=B>2$;!?C50>;.<#3('3/36(4E&)%)C)-<#G/D57@9&)#0=-,3E'A-<=3$3,;;("-%=G3E1E"5AG;GE";F-G0D>3B$%B:!+@(7'9:%-:49?(=4.+B*!:A0+&"B(H,9B6!C*"
@r696
NGGNANGCTNTGCCAGTTCTGCTCACTGCCGGTCAGGATCGCCGCCNTATTCNGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATAATGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTG
+
"$"!*$$)&&#+(*!"#+%")+((*(&*"%+$$*&+)&%'$('"$%'"!$*#$(&%!%"$%)#(!'(*'%"*')&'#(#&#!("'*!%!"*++((!'#&%(''"("*(*$!*"!)*)(&&%*'(*'"'")#$%!+('%&)'&+"*$(%'))%
@r697
NTAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGACTATGCAATGCGCTNTGGGCAAACCAAGACAGCTAANGATCTCGGCGTATATCAAAGCGCGATCAANAAGGCCATTCATGCAGGCCGAAACATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTNCCCGAGTAACAAAAAAACAACAGCATAAANAACCCCGCTCTTACACATTCCAGNCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATNTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTG
+
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
@r698
NCGTTGTAAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGACA
+
+($+!#$!)!%!'))(%!$"*!+$))")$&&'&&&(#(*+$!&!"$!(+*
@r699
TTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTG
+
;%3"@5EG55!.%/<;;/*'@'(&EB'6AD!16738'%=0A)AG9-H?%3&<97-93B@'!>=E69@C,'BE!#3D14!,5!88B-3B
@r700
AGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCANCCGCTGCGGTGA
+
D0C/G9E+53?"3D1+*-1F4=<9&E>1=FEFGG+88?C>5@4"D/3B-49
@r701
TCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTGCN
+
,DHD95DFD%%92F3928GA=<&1>6;*@36A?7?&46#'H:
@r702
AGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACC
+
32HE'>+<!+=%*066D#?-;.C99?!,;'8<-*H7/2)3-!&8&#H55'@4#.->5H!+@/:,A.F;4.;BC?86>G1,3);;F%?.B=%8=+9*08-:;A:&(E;*##+!D>+9@5!29@-)8$+-4&GGDB60-8D#=1#5?!,F.$C1A83.@6$79G
@r703
ATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAANGATCGATGCATAGCGATTCANACAGGTGCTGGGGCAGGNCTTTTTCCATGTCG
+
F084$<0*3@,,D%!%2DE./;=$-E0'"B6+HB,+?E,@2("F2G9"E$HH'C#/625930=9B$:A;&)*DA?-43!>$;)325G$GH8*+(F**#:4*(=C;(5+?
@r704
TTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGG
+
3'%#G#)FCB7A+6A"AC-2?7,39*?#%8,/51>H*D@4=3DH4)!''8$>=)8$A2C&#?CGCHFA$4?B0-,,-!0A'<+/D9+4,<G='0?4+-
@r705
TGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCATCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGA
+
,E,#F+>!H(1G2-.0+;%C#B"%.B*FF9C9>G*@3*B05G12++1)(7*8/4E&>F82E-&/"?2=;B=3:5,'G!6";$D&'!/>GB2D36A##3/,+E61=D573!<3>5
@r706
AATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAA
+
%86=F%B2/+@)".#E:2H-B,00G>==G%'4)815%/;!.>E,
@r707
ATCGGGCTTTTTGGCGAATGAAATTTANCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGC
+
A%H90DA=()<-!979:,!C/$00)>96CAHC@CAE,':1B)?H)G.(B4+<@:?$"6#A5G<':#DF"@9&=,6H<+F;6C1EB(G
@r708
GCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCTGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGT
+
<83!<?A73$<??F78!<-C(A5;G903,4CB9E<*+DA2'C9*99'"D;!35126<37,$80&-0)"2,':1,".034:9$%124%)<1G0(*%);-D("1CF5B$F%?<#8%E7BH$'1<@+;8-E)56=*-%F&32=
@r709
NGCCAGAGGGAGTGAGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCANTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGT
+
&.(E1=.4!@@%!,9#2DEGB4@,9>&9#AE1&;7::=4410>3,DE++(F":A&%@,E68'E#7+-GF%*2A5%=ED;''%7:0EC7"EA!8B*&"E,H.5H@:BB#3<*,
@r710
NANTACGTCAGCGANGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTNTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATNGAGCAGA
+
!(&+%)$#&((%#'##"!'+)()*&%('$'&+'((++!)!!!**!#)*#(#)!$+!*)))+%('+%'()&++"*+#$)&$)'%'(#%'#"'&%$$$''$&$)&+%#*()+#%("'##!())'*&'%)'+)%%%!""+$$)+'(%!)"+"$*$"&'&$'%'&""+
@r711
NATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAG
+
%"'C-D)3>'DD4F@1)2/D*"C?E$<1;@93!(:-B,'A*=!"/;/;,%;#1B93/<-4A?G/;/D,='A4)<FE>C0'@H7+CD2B$!"=(D:'":"04?3+,(F,46!3F44,/'.E;248!
@r712
TTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTA
+
"(&(+&*($"%)&*!%+%!$*"!!&(&($')'!((!""'*&(&&"''%#("+*)*&(!"$"&+("%++#+"")*&()#+()('$"!"*)+*$
@r713
GATTCCAATTTGAGCAAGGCTATGTTCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGC
+
;,726962H)$=5+D-C@:)=#<+#).%FH,@BFF<2(D(</9-5A/6'7F>#:H1=.1+?,,
@r714
GCGTACCTTCGCGNCAGATNTAATGGCGGTGNGTTTACAAAAACAGTAATCGACGCAACG
+
':>D).H*>@5=F6EC/%BDHAD2=,%/B1B&8A!D#&&C=C&/E96%$"B+C-B9%>&7
@r715
TTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGNGAACTTAGGTGTTTTAACTC
+
9---2945-)+D@$!7C/H>*'(<+;3",8(A@5*$$"F5=/+?!)?:6122,)220==4<8:<58?#DE)#C$H+.'2C6>9G-1!%:6;/AA>!9##>;D/>E7(B)#=5B4'*#:$>8920)
@r716
CTCNGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCNTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGGTTT
+
(F@D%>,"A/&6C;%&D3.7.%*%952AH6:>&64<&/!>CA$C"$!B%1@4$G>HGH1@+2'4;<$)"#77.0737:6/&A,3#EC!G48-)$"2,;C+H2.(1=6;?B0#96E>%*/;%:0AC%&>-:FH@H
@r717
AGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAA
+
..(7)=-61G.,E.4A=);E/6A6#D<?7?E'8D30C731A>C$AHF5F)4&8E<1#?72&""H
@r718
TCCTTCATTAATATTCCGAGAGCATCAATATGCAANGNTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCCANATCCNTCTACGATATCAGACGACTTCATTTCGCATAAATCACCAACTCGTTGCNCGGTAACAACAGCCAGTTCCATTGCNAGTCTGAGC
+
,E9&,@:2B-E',D<+7E<)H7$(,E8#G27(14%&,%>3#E2<=BE9@B:!>,.6$.?*+F+8#D8(C*C!<A4>$@>*=?AC?H3>85)>3'8971G(""56=42+=:8$,H>/G#C$H'FB$<8?!B$H)"7>3>@"A"3;C3+EB".+?.(;"H.D%3)00;50+
@r719
GTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACA
+
-8/-FBH77B;+,%C">@A6(=#>@%<9)9!%@"H=9>&$,G%=>%02&.D474A30F>/:!:,9:%/20).D<0C'-:2**8)*+3!,!(CC=8#!6'<:2F308%+7A!94H4:''+E55)A'65&@:?GDDE;*G51".8#=2B536GC'G8-18ABH5,!B%6)$+;CB4-*@<>A##;8A2F2@%'8$//
@r720
GAATGCTGCCAGCAATAGTTTAAAATCANTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTNGTATGAGAGTAGATAGAAAAAGA
+
;@,9A"8?.H)/6<%+9-7!2'.<67;B;"F)<3D2FE=74"<D./()A!A.(-9.E@D?F0/)$;:,6:+AA$9$5=*$<00D*'16?60A,3
@r721
AGCCAGCACAGAAACATCTGGCTCGCCTNACGGGATGCGACGAATTTTCGCCGCCCCATAAAG
+
0H*"@<8,*!0!B4$/E&@"<++:4BA$8A?:'83+H4/D?4@2;'))(5-B=F2.$H0"B76
@r722
GATGATATGGGNGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGCCT
+
(6<56::+$5$#+9)E8<'E6"5</0;HH:D#DDE/"F8DG!)E#*0<?B>D5/4!'4?.F*<?F#@(3(F.0D950--:2F23F65'.64%>688&D#.+5B);0$31$4B6
@r723
CATCAACGACTGCTACGCCCACTGNATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGA
+
+B2AH<-F21-&1!3DA18/F.(0.2(AEC9B59<,2.304(92B+4D=&&B#'-E&(!&<)),@"4$)(05#C3#(*";*2G
@r724
GCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATNCAGAAAGNTTTGAAGTAATATTTTAACCGCTAGATGAAGA
+
9-<2@$<$0/5:'"6D8F"3C"H760337,*E%*H"FG9'C.8@,G=G$<#25':!F&)@HE1(;&-?:C4D+0:>;7;-1(C"81>F:3:D(*%47!-2:6%'):(1))-4(/
@r725
ATGAACTGTCAGCCCTGCAGCGCATTGAGCATCNCGCCCTGATGAAA
+
"/B:H>!E0.$*++C?DG,/"1F,D;'GGH:?#7(3.6A''2(;(H/
@r726
CNATNCTCGANGGNNCNCNCAANAAACNCGNTNTNNNGNANTNGTNCNGNCNGNNCNGNNCCANTTACCNGCNGNNGNGGANNNNNNNNNGNNNGACGCNNNNNNNNANTGANTNGANGCATNNNGN
+
"""##"$#""##$#$!!$!"$#"!$##"$##"$###!$!$"$#$"!#$!"""$"!#$$""!"$"$$"""$##"!#!$"#""!$#!"#$$!$"!#$"#!"!###!#"$#"#$!!$###""$!#"##$#
@r727
NTGNNNCNGATCGNCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTT
+
%)(#($'#')*+""$*+#&&)&*#($!**&)%*+#!&"$%$$#&(%*)$)*!#"#*!!#$++!&%"#!!"$'*"""#)*#"('#"++('$)"&!"#%!'+&(#('+**)+
@r728
GCCGCCGCGCCCGTTTAATATCCGGGTGCGCAGGATGACGCCGGACAGCACCACAGACCNGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTG
+
81=#@+33#9A8;,9G0F2=29(B1("<%=8:C%1,5/B=:H-H,*6F.=@8"5!;#=B*#D;,@,D/7'37***.C46%F*<<H7'G0;4/;C%+G;(?)5,292H'B<;&*&4?6H(/G5"<;5<4)7C"&7E5
@r729
CCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGN
+
.-/4HE?*1,,@"3G"8*2<DH1263B.C<'@342(2;7.)A6<&"@@C?=H5B"0(/H2)C(80!@43,G)&38,3#-;G@(@8CFA@2'D@CDH4E9#/;;$:,6('=C<H<3@$F0'?&#&!;465)D0!=%B193D-;?,'54A"9@@"('9B'A0<":H&B!6
@r730
CCTACNGTTNGNGTNAGTTTGTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGGCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGC
+
()"&##))&"%%*%"'+('+&$(&&#""*%!!"&%'$'%()+(+'$$+')&"+)*!%(!*(')##&#%%*"!)!!$+%'%$(#()&'%)'))$$#(&+!&'"%+#(#%+"&")&+#&(+$&+
@r731
TCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATNAAG
+
",70!@<;:?$CD)"5.;%",0*91G1@"-C<#)1$%/1AAB71$-5G48@F0(31@$9C!GA6?#:C:?71$"
@r732
CTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCA
+
(==?9/;GC#E0-,%B?,A@-2=/BA70((A97/@G&AE66!2F6+!8A->3DE6*DC)H-)(@#F#,0-4F4CB04
@r733
GCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTAATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTA
+
>#FA>2@>250<@#!-9+C3-1!/@82*6);//68DF1B<0G5+4G2@:3:$*A3.D#EF47.E:/12%3?0G40>?HF14!2F($%(<"-=83./,;1G'CE>G6@!1B&?E73*,$=!-45@#33@;BH>.(E83;H>('3)+4&1+8=4C6!%%#961GD&7!706(6CH:;%A6H%E!5&/>:'=**?-.,;#1H;3@B6+?&27F9:
@r734
NTATNAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTT
+
!0.%C;4?GD608+5.-C<&(*>-@0*5'B97,@">B!#E4(2%&=G;+=D5!D0GDE+&=+2;8+)/?#=)/B(G/)8-68,4@#C9*#91853?4=>G'28<C;==6+,@.:C
@r735
ATAACCATGTGGTGATTAACTACGACGGCACGAACGGGCAGANAGGTCCGGCTGCTCTGAAGNCGGTGTATGACATGGCCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTG
+
1B<H/!&!$*>="#$G4A!?C,/#:*2<.4B097A2@>70'@AA?=4GG62#*,G1%;<1A$CB8,#7'6/(C63,71%C;>A-3*$))>@546<&/C'3$>19':=?/G*7':9DFBH5+#+#G?)8A(A/)#$C$2G2<E@5;(6$5C;E/-#%+%>)(22=%B0H=:;!#>(D=C';:@;/(C
@r736
CTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACA
+
G,+4%:9@?3:B+@:A,3.7"C;;0>%;'=3&(7=%6E.7(%,%+E(11C2">25'!7.35"#6
@r737
NAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGCAGACTGGACTGCGACCGGGCAGGGGC
+
$%*'&(+')%!($+#*##*#'!(+('"+"*$&!'$(+###%*!*$&"'(*++*&)+*%(*'#)''!+)(++"##%"&#'%#$#)$(')*(%(+(
@r738
GCTCGTTGAAGCGTACGGAAATCAGAGAGAAGTAGCACGCAGAC
+
#;2-H.A2)@";;E&&-?<-CH890A%%2AD#(?%/2-C64B0F
@r739
TTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCC
+
(<3?,!?CE6E->(128EHE%A<%"+1<'CE4DDH5=8$4H3/BH4HB:B3&:01F4=B+@C0(?A3:B.F>-A*!FD@**?F6F,CE0A&#=#4G&D@9-!E@=4#BG0F!'C/FG4$D?$#@8H)$+4%%8?2GCC1(*3C"#?"-39D87.;.0C
@r740
TACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTA
+
/"FF=D$8?%*>*H&("$(48C?G,*<--0A5/$(9C%E2A1+::+F
@r741
NCACACNANGCTGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATCNTGTAGCCGCTTATGCTGGAAAGAAG
+
$"(%'%)&&#")'+(!$(*)()++%+(!&&$"#"*)"*)++))**(!***)%#&"&!**($('(&*%"%*)!+*&'$''*#*&)&$#"*+
@r742
CGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCT
+
4(-*6)*!:;/G+DG8#G62+618&'FD:'7&A;H<=&-11,%%,7G,F8CFF*=8D%(-"B3*!5!+1$.B99-<&C"7:DE=;7C+?1E>7"@='F24.%2,6=,:@CF68(9!7#/05*6+4+)/9.3@,#-<&'&,#%7.F06E=;:*9#0(;5)*?=8"6C10B<%')41D@)5$74(E(<%%:)>A!>6;.;GC:H'(3H.&=99$4-;;(.?>"3"(D>@#D#;@>G<74G=A"C
@r743
TGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGATTTC
+
A!&@:@21/921#5E9D(44=HD(F&+7F4/:5#*/B:E#H@/1$53?;.ED<$D-(2)!204C.=*13B"=6D*%-.7<8>%%6:20&%7F$:=&;F49.1*%*&C*
@r744
TTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGT
+
DD'G>,(!"2)#H0=5'9D?G=<0'*817;.8?.)3(A@,C=>@;39DB0GA>=09,F13!!&-;
@r745
TTCCAGCAGCTCCTTGCCGAGATGGGATTCNGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCA
+
E!59$+6'!H5.0&<H-"-<B@(A.#%>B>;(*+E816"<D(2@'"<.9"()49+4>&%%70!&2.0?E*5=:
@r746
TTCTCAACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAA
+
-C??)/3)F(@:!C53D!C8=A7&,0(:7$'01-6%4A%+A2G>8-<?$BB
@r747
AAANGTGCACAGGCTCTGGCGAAGATCGCAGAAATCAAAGCTAAGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCANAA
+
*!!&+$&*#&##!+*''%&#'(#"&#$'#'%)&%**&$&)&($)##!%&"%"'!"$&(#($!+#"("#(#()*$()'%%!($%&&%!)('!$'&!&"*""&&***++&!'%*
@r748
TCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTNTTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGNAACTCATCAGCCTCATTT
+
.F;65#546"#E4;E)=F=7=!)=H*-;3,#AG-7>'!GA3@?@&3D&>7:*,*BA+.H+2?E=?C<F7?933,47/+<5/<F(5')1$(?(BC<D9A"1/$H>.B;151/9E/%?B/F/5=;60#08D+#(3!32'F$6463"$F,=?D()?-D?&5=C)(2-934611)?>73#%(9!3'*AH>%(;%<-.%/+-E#=+6C7G'76"'0)(>'3$3B9%)(=GC:
@r749
GCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAA
+
<3:"8'H=69.9*%A?@CC9$$/G-$CA1&.&3!!BFC8DF1>C3#<5-%%4/E?<%<=G&496.3F*GE")#%03576;&2EF?DC)091
@r750
NCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGT
+
'<!B$F1;,%A-AD/@71HB/C>;#-3D/#44AH7?5*H(=!'1G7F#4;>3"556148%,=0:2":/
@r751
GGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACG
+
A*#%0D8CF''=6H5%4E<+H8-!$+A:.(3-A2A%#FG+,?",'15)B&E6-/5F%6:7'>1A6/<A%3=E0G+&9-5F$@D9
@r752
GAATGNATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAG
+
#(+"+"'+&*#(&*'#++**#*(#$(%(!*#()()*"+)+)'(&$#(*#('!"(+*!
@r753
CATCAGCTCTGATGCCNATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAANCTGTCAGTGCAGAACGCGCCGCC
+
F6:=#&"&"=H,'$$1;3D'/7A/0.10?E?-F,A8.F#<49#84%@:+(A+'C><2$D0*F*<#F'6=BG49->>"AHE$8H0/<CD7A25F%9"E<=/6D+!6&$F,
@r754
AGCTCATAACGGTACTTCACGTTAATCCCTTTCAGNTGACTCA
+
,<!?)F2565DGA.HE/7B>9H:+H#).'*%-#,41*/H=%<1
@r755
CATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGA
+
3F1?8%9#42>)2<5F5*5&0A-72$-7?H=7?D%.1,4-D4.?0>&5B.9735=/4?3;25
@r756
AAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATNGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGA
+
H6>9>1<0)/730-*"5?6H>&<=$)-E?;;G092$H/&F!);5H*(#9G08B0&G?65E;+5G";&CG#B(&HF;,++E#G-#<H5*/FA&FD=.'+2&C+4476>:H-'A=,3&95;%D#,0"G582-94@+A
@r757
CTCGCAACATTCGCTAATGCGGGTTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCNGCAAGCGCAGCATATCGCGCTGTGAC
+
,>64)!&,=<F/>>A:=8/6A.(2/1C9<*0%,4%&H##A3E800&D."E;9D&3/G5<$</F(D!<%-.4.*=7=H67)>(,%:99CF8!/<;.9>"<+EE)'."'.3%@.(8:%BA$4D"8#>:=6B!9D&.;6$&&-:7(;6.:3AD%</%FE0<0H?>@E$D)HBB#5<'8'$,B6"GB6%+6*>:A5=6EF753%
@r758
CAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTG
+
-G1B0::10G98F?0'29.?H:65>9F'-8>F+%>-)3(7(F?(F7-B#@31%5=*6,8@:0
@r759
GAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGG
+
+209122!H5@?,>7!58@6;@0&.764@5197E=/C>%)712%&;8A<*#H3%2E.37D..0?-5CA5.=)9>6H5EG0E!C(*3)79
@r760
CNANTNATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCAC
+
"###&"+%*"*%""&+$'#+%+&!(#*+"&"&#"&#%*%(#)!"&%"&&$&"#(*)'#"+"(!)+++!+()"#$)&
@r761
ACCTGTCGTTCCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGNACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGTGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGC
+
E!<-B.281,@:9H;+)#>/1*?#('1(!=AC66?'2:2)HG@(FAH:+$4/D6>A6F(:+8?!&*2@@$F04!<D$$?A#!!*7)=B'@!"9G!E$8A0FE.11:F"='%7*<H+;%(0=,6E4,65)**&52AA,0=3;*9(,+D23#<4%<G934.'AB+*+G!;?&*<8*@2!:)6-?3.G&.<0E:G.;/.E1>E8+*,F/,;2F@!-"*B&:(%/(82))C9BB&5>A=*D"%>?,;1'!C)B'<4B55/3##,D@=-<%FA9()+C
@r762
NTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGNTTCACAACCGGGGACGCTGAANGATTTTCTCTGTGCCATGACGGAGGATGATGNCCGGC
+
$09-9-1G!H2DH?&$B&)F,:0../7"<D#;8-#<-9(1?+B<GBG&0C)<$(A<#8,1.H:*/+E7.>0"1$32-7/@,'."&6$$C"H(3+!7;D$;?/
@r763
GGGACCCATCGTCTTTCTNATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCGGACTAACTTTTTTATACCAATGTTTAAC
+
$#+!!#!&"$!&($%)!+%*(%(+'""++(!)*!))+'%'")"+++($)+%'#'&('"'%'**"!###&"$#))))&+&$%!+&*"&#&'#+%#"*(#&!"%
@r764
GTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATC
+
1:+.?"<?7E9<%<-$!F.1H5<+E.*&62"<*3H5"4@5A$A,;
@r765
CCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCAC
+
+'#%&(&"($+*&)*$%"%%(&#'($'#$("(%"%!!()($%&+%%"&+((&'#'))%+&!))#%)$%#"
@r766
GTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGNACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACCTGGCC
+
,=H+@;@9B*+)'58'(CF5&AD4B@!G(90.)$C7$'&7!7353B3&1HH?:C!F%)@29=581.6#?>*A5388:#>:0983(.+E$-:5;((+./=E:;5>/"=#'282>:154:2H3FC2DBAE+9(/<B1?6(606
@r767
CTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGG
+
+C?2EH7:F<-(D#2F?H08A;D4-):B(#;/%+><31-%)?A7,'<?&0';0+7:6@6<1%6B
@r768
CCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTNGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGC
+
0H"40*&$D%EF7:E>D%1/"8':9@@.#C!C*'=-*42D="2%?+,*+8D#(/>*$+;@<#@9-*);'/:'3AF"9E93('9'+A:>+8.60)F93FAA;?:;7C&17?#A+'A)-G;19>E:&63&9!F,A>9#<D//?B88E053*:
@r769
CAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCG
+
=$0+.+%&5;3!E!0E)6>=A5*8,?B&G-",A38+26;;0CA+E&%;-29C@4,<;@;'%
@r770
AAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGANGTAATGAANCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCGGAAATATCTGCTT
+
:@39+@;-A6>#A@H&"3*98=.11,$1&D@4CA?(>!645F0E+2.1+=8A)9()B&1D#02*+3+:),(&(H>=B*1)2!;!"*E.@=&G*(+:HG=4;45(('E:;E:$G+>GB5%97A/G
@r771
AGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGATTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCCGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGNTGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGNATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCG
+
C2-->-""A&D5$@)99A=#@3&*9?.<3!#'8#EE"=06%(5;8C6E4G*181D*2*E:$8(908<3?3777#6CA)1D:(GC21@4%:"*4&;,C94?<$$'%/2.'3C->4#->5@<177(+%(%9";?7#3CA-&!F2=8*?<G08$'07#;$H3.A*,A'8*>.-.3(.'4,,2D@'G:0E79F5)0B";G@4F4G,#2$(HH<">1!0,!C3+/(7<H88B!78F2F-1D(""(H,EH1&469#(0B</A;C(>-*#A,:530-46>&$?5$1+"9B>34G6+H$EB716#H<E6H8D/!'$2#;6B9?,799H%3B*(:>8H=?:DE:G=*)06.9$0?#@093$@
@r772
NGCGCTGTTTTTCCGGGACGTATCATGCTGGNCAACACCTGCACCTCGACCNATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTNCGATATCACGANGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGNTTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAA
+
$0E.?<-!%EEH.(8)*D%9B@F/C1-=15(BB..F,6.>-4BBD$H(1+9A4>.D5D6=2(#>%&F8+1;;C0*.+&3B/<022@8$/9,'%.H=H0'=4.A*EA$=*DHB-E:.<6$;B;2$"22)!>.)+FA.?'(0HB5F0CF#/1@<;,<-1GE-D>*D78FBE>%7F5<.+>A$<$*$&%0)$@;+52'<%!;A408-54&;#(G>'5?8B-D-.4'!=)'2-A@<=33;?E@"9'H.5B)&C8C)0=A"*3B1"(1C1CC0$D7EH0G"$*"F'(E'>)5$@8);*:53$-(@G6/B+F+?+6=FA?3%!0/-H<
@r773
AACATGCCGCCTTGCTGCTTGATNATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGNTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGT
+
.";<=:!0G;F%=8:>=D()@5::C'9$1*EFH2*37@>;?A?E.D#*$<H0HG,!#8EE";-;;A!-G6#;CH!2">"2:B"/%;#/7#67$&$?AC>6#*5"+090F07/-@?;;8?<:0/$?87G6*@58;8)(@&,&?5E9<6!.&?FE"9<%6/',0)7%*AD7F2!H$
@r774
TGAAACCAGCACGCGTTATCTTGGTACGGCGCTGNACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATTATAATTACTTTTATATCCGCAGTGTGAACACCGTTGGCA
+
<%0&9%5?;E1*=((A0&>!@9*($%?6-3-4:3?-*C4;E#!%"/4'")B8.?+C'&6'B?)A=.<8)(0<H2>?+:@(,%903>88/D;5+0!$'%0,B1/D1+8B7:=8.
@r775
CGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAG
+
$*;+*#!(G<6?8#.2A8B64&D/=A(!/!-;A/>2=5-C*#!G7%7H6=(<$$0?GC@!=?(1$7?.53B*A30=C:57+)FHB..93FGG182-+?0>+1&+-6D,;6/+16+<%<.7D>.;*
@r776
TTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCC
+
E$:-9B-%@>3>9$&D64B-$E+)@:G&<2-B;'E,:$0>@26$6;$C#1DB4.$1*..7BCEA%,@"4547%H"
@r777
AACCTTACGCCGGACCACCGTTCCGCCGACCAGACTNTGCATATCTTCCGCCATCCCG
+
G#3B'7!7B<4!2G%5,4(?C%+*0>@A=#(G6CB7-$6@D>,?363A+AB%#*"=%7
@r778
GTTATCCGAATTCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTA
+
FA0+!/H!91>C8*7C94$>'%/F$20;5.@9>!<&@E7:C+)=-3D6@F("A&<$*&B9B4CB5;'47E-2GC8+%&C;77"F47+9HGCA2FFA6E,:@D)>.&GC#$4;CE%+:BG'%$?6-9D;7&:;D,8.F*@8(0F#!D9,;1"0!%/G=<
@r779
CGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGG
+
>%@26-9G)='@417A@/*+:A3A/.##8CGD626F4A08<C24G*8!?.-'%#()./<G=-?'=A*#65H7;E0==F9>=,<56E:F*>H1AH:*!A#8+/'+"BA)A73"!7B>>&#G-"9#.G@,-G":;865-D#*!=-==C45.
@r780
ACCCTTCATCACTAAAGGCCNCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATGTTCACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCNAT
+
$-&<&H6/??@B"))!B96#6;;CB2;40:D:(<>!E3"346??)CE&*4/&9>G=5B)3A(9G>@3?*+$<A2!H@,58A2*0$:H4-8F16%1#3.FFH(BF#?35A9DF#!+':F#+!-;3A>0)9GH5+%A8699-+'!A8"H,)$9B()7$G-.0A.:E/>E(H>*$F3E
@r781
GCTCNGGGACACCNTNNGGAGGTTGTTAGCGCGANCTNCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATNAATTCAGGACAGACAGTGGNTACGGCTCAGTTTGGGTTGTGCTGTTGCTG
+
)#)&!)#!%%(#($)"$$%+($)#)$')%#))!%")*)'*#**+#'!!$*'"%$(+(!$+(""&$+%'+)"$$($+)($"&$"""'$)&*()#)+*&(($$&!!()(&(*$#(#+$#$%%&'+)(##$'%'(%($#$%#%'#()$"'
@r782
TGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGNCATCACCGCCGTGCAGCATG
+
&D0E>"%=0).+?&%?)#@6F53$"(C,0/"$0$,"<D@2@#9G#?@4B;CH)1G015
@r783
AACGTTNGTGACGGTGTTTTCCGCGTTAACCGNAGCGTTAACGGTGATGNTGTGTCCGTGTGAACCAATACTGAAAGAATGG
+
&'$(*"#%++!&&'$+#"&!)$!)$+'"!!#&#(+!(("(%)*%%&++"($+&+"&$!#)!(!"%*&")$(!'%"!'##$*#
@r784
CTAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGA
+
&%41@.!#7)+5=*&C@1BE#9*7((E8H56>*%747@$B4H..!-/C%3+GC9125/0C7F28/5(HH
@r785
AACGCCACGCTCTGTACCGAATTCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCGTACACGCATCCTGCTGGTT
+
1@!;23GFGF6"H07%F,'*D#<7:H8*"+,/8'5+&.+H,7#!&,1CC="%>%9F.,!1%?!/1F%(,05*",C;
@r786
CGNCTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGNTGATAGAAGCCGGACTGAG
+
()$+'##%%!"&$!!+"'(%**)))"+%+"&!'!(!&'(+$&"'&"$*#*''*'!)+*!*"*'$#&!*#$!&'*$)''!"'%$+
@r787
TTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACC
+
*/D"0C05:032$%4FHBE4C%)#&EE4G17@<31&BD%$0:/.B*+H%!6>=D;F1>G8"F#CH%59<-!:48B-DH?
@r788
TACTNGATCTATCAACAGGAGTCATTATGACAAATACAGC
+
###"%&+)&&'+)+&&"%('+$#+$$)&%*!&#*!#*"!#
@r789
ATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGC
+
1/H:95,A@!)5H%HH17&9<3:#!1.'**+3G)<G2;DBF4/H*31>//1.5+7:0:D0C,(4<*EH@CG+
@r790
ACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCAC
+
-%7/?9/=D3@C41HF1AF7;'%?3'GGBA(G#->?ACH4<6#
@r791
CACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGNACGTTCCGTTTTGAGGATGTNCTCTGGCCGGAGGCTGC
+
0=+%:4@E.+;FH/<E71$82B'FG9,&/.A#$$HEH1*6D,4('B"6'9.'4G=>7$?3"20:'1@;@=6G;0"$',>B89-9>5%=+$$<50,1/H#/>*;1=H4%H.11*+6"'
@r792
CACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGGGCGA
+
>F>H*+/*<0$!?=8D4?0%C).")('?)*D(9-"*@F<)<@9(3A3=(A9@!#G?8A:,(+GB9$:.H
@r793
CTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTT
+
8:@3@CA)AC2%,A;C7.8,'";?!B=+*8"*A%40CG6?4
@r794
TTTGANGNGAACCNNCTTNNAGCTATTCAGGATTTAGTAGTATGGCCAAATCGNTTAGCCGACATTGAAAATGAANGCGTCCATAACACCTCATTACTTAGAGG
+
))&)*"!*"'&*(%$)*('+%))"%*#(!!'*$*(+&"#$$*$'"#&#+*!(+##)*)%""!%))"+*%*$&#&"&%($*$#$(%$+$''!#+'"$!'%+)#$%
@r795
GAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTTAACGCCTTCATCAGAGAAAGAGACCGNGANTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGAC
+
%+*+*$*#+#!*%%%"!(%*)*#"!#!)&"%'+%!'#("'+$!)+#$#$#(#$$'*+'&"!(#"%&+%&%%"*%$(+)&+&""(('+)+"("!$'++*#*)+$&)"&%)#$!$'"&#%%'!#!#"'((&#$!'**!)%)!#!*(!$$*(*(*((*%!"#'$"'$%)()$$#")%
@r796
ANNCCGTCCNNANTNNATANNCCTCNNNNCNNCTGNNNGACNNGNTGNCNNNCANTGANNNGNNCGNANNNTNTNATCCNACANNTNCNTTTNANNNGAGGTNANCTNCGNNNATNNNCTGGNCNCTNTNNCTN
+
$"$!"!#"##"!#""#""#""#$!$$!!"$#!$$#$!!"###"####""!!!!!#!#$"#$$#!$#$#"##!"#"$"!""#$!!$$"$"$$$#$#"!!"#$"!#!!!$#$!#!"#"!"#$"###!"$$#!$"##
@r797
AATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAANGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAG
+
C=7*?$+D+)$8=#->*';%0=('%8;1(#1A?1,<8$'."EE&-<+A!+=:@A$(26(9;AB9??431,A%!>;(E0@2H;F.>,,"9'*:@"9*#*2@%66;=;'25G7A4ACBC"ED!,5&CA/)&7-@4H(1A$98D5F,,,4:005*?8?0'/?/(3+;D@E)"HG$&H#'%7"*,9)+FB66D06H?0
@r798
TTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTGACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCNGTCCCGCCTGATTGCCGGAAAAGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATTCGCCAGCGCACCGGTGGCCACCGCCAGCGAGGTGGCCCCCACNATCGGCAGGGTGATCG
+
7+,%#C&%(?H-?;?99#F(6$4;+3598@=#F&%H4"9094,$E4;3F,F@@"97G/E;C2.H24=50;GC8F><2FH$;+&72#+/1?641/<A0H<49&ED'H79(8H4G7%(+GA-(/39313)3<@=5G#5C89:@!',8>4*:;F93*!92&.0&DB;(F$%/$3$2(0D3H3EB(H(3-E<3<5E&6::;DH94')4!:.G)0A5:,8>4B1;C%HF>47910;(>C:.)3*.F/;G70E)@$!293%A9-*2G$6G*%$(0,"GG?8E&*'AHB#$C:H6GB>"5@3"+-2F"&6/@-ADFE<'1*G%7/(2"2%BE-:4E8$)-"+'C
@r799
AGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGNGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAA
+
-!E##;3E&.$BD/-A1G58)?F*54:E03B5=45*:'H,.#$<*(F396??74:E@C7G2'!):D!41-#A8G:3H40F;C>>'938#FFG<B!0.(A(%6"*G$53!+7BA=#),&>!*#(AC.1,2E"66$$93,&:%%!")A1)3G4<E=3!$-'5G0,(..7F
@r800
NATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTA
+
&.(G?<1>A#30=2;*C6>D8?;H-06A327%"9>=%'*>:-&0"B0$;&-
@r801
TGCGATTCCGGATTAGCTGCCAATGTGCCAATCGNGGGGGGTTTTCGTT
+
3ED)%.@5487/./GC/)<"<B)4F-"B!5G.C,A2E.<A0BCG@2D-'
@r802
GGANNNAGTGTTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGNTAATAGGCCAGTCAACCAG
+
*"*#'%!+*&%""+'!)'"'*%#)&&'&)&!"#")$++%#'**"((&#*($$#(#*(#*$"%&"+')"!(!%'*&!!#$#&'&'%##+$)
@r803
GCTNACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTT
+
*%)"+(&%(&('%&!*!&#"!$*+*+'"#"!'(('('&(""()''*$*!*("#$"'#'&(!!)($&($&$+*'%)**(+!$()&")&'!*!*'&##&'$'((+%!(%&
@r804
AAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGC
+
=@.H3')<6G70%(;)A56:>(071++==A6G))<2F34+<EB:;A008!5A8FB
@r805
NAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGTTTCTGGA
+
"B<')E%C?#3B:(*6B,3*2C;"2'/<<2&'21=E2("2,D1C9E@'BC$
@r806
CCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCA
+
E>>'>99=?*!##F$-"64!A;H.8<D5?DGE9=F3%(*G%6
@r807
NGTCATAGATGGTNGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAA
+
+(+&$"("$+))($%$$&$'!*'+*$'%**#+&$%%($+#%%$%)+"#&+&&$"(&)!
@r808
CGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATANTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAA
+
%2(?F8H/>%9-88);H!.G(C'(,><=0<.A1,94B7)+A&:6&5197.>*F)<G8/3;!*.D%H804@E(E'"*CH<87D."-+,B$!:AF2'%DF<2;CE?#!C!!002?1G5+@43;!+@')63G,C+?8?!2#1H;48A-"3"D/<*,!2G(?$$+FE!8+(F7B#/$A"?-,7+&"#5,"=D$.B*2/F(#D6=:(24/-82
@r809
TAAGTTGGGAATCGGTGATTCTGTCCATTGGTTTATTCNACCCATAGGT
+
0:"=+4H./1%4%0D9E(##A'A8A2'1/6$62>%'E"@"95++0-E>2
@r810
TGGATGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATNGTTTTGTGAT
+
3CD9D1<'G/79.2A1;0'4>?F6%6>)&.?*E)3/.=;E)-*8DH@>"?F77"%.H/.67!G!9C&'=%/G#81E'D8+CB%1:!AH*24@-?@D#@6HE032)EG
@r811
TTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTC
+
3A*B?+)?1.@((::(2C5;75)9=4(0>0?+=<4G9*%@=;02>17C!.35/7/@,>*4(46A,.!3-A+<88F,&<24'';)=F7C.;!@+"AH14"C=?("=8%6072(2<>//>'2GD7-2C$$D.)"DH!&D-:8%#6'A,)%:#@:;B;D9:A@<D&+$3H<B9BF4'%7<D
@r812
NCTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTA
+
4?0#>),-$085&$(D'#/#!B0(*")E37=EG.AE10B!*H%A1CH37<*-G5@*)<?<
@r813
TGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCNCCAGCGTAAA
+
@*-A.GEB2550FA;/A)":6$%7..?&B1%".80>'$HB0:6/0=/!"&B(@*C"DD><13.%1HG;<D=(4/)5%"+<>':/.75)!+D(-:E4#=!;83C14,4-4/,"@2@%4):G0.9"B$61+03;(3#1.4G<=%;&<!E8=E<>7,+A8!2*=3A909<&$C*=.#3?F8":*F
@r814
GCAATTATGGTNTCTCCGCCAAGAATCTCGTTGCANTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGNA
+
5/=?DH&D=&62H?@58=)8C/,B-1@>-@%G/:::%H!.=365DD.-.A@5$$G3(<-95F22:@0%-0@!<8F/"GD/;A
@r815
NCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACGCGATGGATA
+
";3A>!3?/6-<+8!'719H2!#C&#42="=H=85/%)'#+EC=<#
@r816
GCTNTNNTTTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGNTTCTGGCTGGTCAGAGGATTCNCCAGAATGACGA
+
')%"$"!*(+*#*+(('*$'$'())'!**!"'!*+)*#+*!&#*)"""&*%&(#*)$*)*'!$#"$#"+%&"&$#)*((
@r817
TCACGCTGTAAAACACATTTGCACCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCAT
+
"24&0C)1/&H2=;0H,DAA&9/5-3,!(@&$'D+8E76;)6752(4##8+%2=*?>,>C4%-#-9E;53.2F*5=&!6D1?24=;/*22A0G4B*).)$3$(%5-0EB-BH='A<1'4DFA
@r818
CCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCNTCGTAAAAAGGGGCAGCGTTCATCCCTGANAGGTGGCGGCAGCGTGC
+
6D>>5!=6-H72;*02B/5!<57-#.))441D5;=E,48"@<C#H9C6/2C&G??1B4BG98)&=A+5BF&.*73;*FD2>;9'070A22F01?@3')C2CH<?7&-$'((B./-B#7(4-0;DG&G8->:#)
@r819
GTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGT
+
1+>F*+<;(5-7B7(($.8!)1B7HF7DH2*35'%"8223F<488A6.)4C
@r820
NGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAGCGNGCTGAGCCCGGCCAA
+
&-/#?A=8-4,*4HE.4::E-G:BC8>80$?FC5?@F<&:83AG'C<76!0@$##<.D
@r821
GTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGNCAGACTGCTTTGATGTGCAACCGACG
+
?:B6%,!&'/-?2F85.#++@D>4#AEC)6-B0/3B)$*7;.$G>F):#11,:=C"*#4@,.2":H&B<F(=B);C(C"0390H1
@r822
CAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAG
+
6HE7>'H!3182-9($*CA/FAD,>5"5??/&>A4=85B1:@9&<2"0(CG55>22C(B8H:<
@r823
GCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTACTACCCGAACACGGCACTGGTCG
+
;G#!E+C9+.A$%B=-0B!A.E(+=1A-5+$%3G"5"B:ADA8%E+*%$"@(&=BHABC+F14A'
@r824
GAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCNCTGTGCGNCCGCATCCTGAATGCAGC
+
7G7"5?$1D>C%(23@:B1,H4%2&..9%H!0?+@1E=#:GEH2>%-D%G@".D$*-B;38H!BBGG)E3A?FD9#H!F$AD&>"3<-B4.&=<-;C;(-'>2.B?3;2H975%E?G-9;F/-@67=4>#!)BE@8$$(;1H6#&4:;66H)G$4<&&48(,6:4FF<B&H;9>6GG1>5'$-=-<F##G58%9E%
@r825
ATCCTCCTNGCATCTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATACAGCCTGGTGGTTCAGGCGGCGCATTTTTAT
+
DA5;/7;'$";)>,;?-6'"!017!>H9/96G.+8C'1;;"6#*>>-:/25%9F1!F7C.:#C*=>2E6D86);<,1(!&4&5""(&.25->=B'87=H.'>'4*:$)<7H(-'64,0(1H:$7.$?&F
@r826
TGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGAT
+
(0$10E)2-0GD+0!,3=><%/;<@>E202+:@7=-G>5&@'*B<;GAE0$$<F.=CBD!(,>->A+1)61$;;&?AE/+?">@=97.B(87$/9F/=?04H"@:;=>C#,1E?65BHE)C50*B-'9CA"1.>):9EC2D0?0!H7$.=),)C%#><E&&0/=8
@r827
CNGNNCNGCAGCANCNCTGNCACTCGGTGGGTTCCACGACCGCAA
+
(")$"%'*!'$&&"(*$*!!+'##')+'$%%*%*++"()%!##$+
@r828
TGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACG
+
G%E"F"$$2?<EH*9%:"6,8:+%BH5&A2"(..+0:&F7*C&;C;=*'0/!%AA$:/E9243,9E.?+H3'1<4HDH>@9',E4*!329GD@!9;24
@r829
TCTTCANCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTT
+
=D,3?7A5%>2="4!A&#@F%1-DDA)48'%A2?'>BE*>(<AD*F,8<)""E9DG/97CB4788.CD''+4AGB@#1%'E+>4D$*-=8H:-H&8;3C,7<2&).65+<H.2+,#0A#+F5#!='0"+5"BD-=(!''2E7AF=1<;/(D.'8CCFH>6(EH+
@r830
AGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAA
+
GD5B>%10.H5G'.;$6#=41,/A04(C)2E%(D=4>)*B1"5:G5/:)-=;)(,"G3,;31H)%$)-=7
@r831
CTGCAGGGTGAAATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACG
+
%=8),'8>7="684*G;:/(%3&B,?7&7.D.&EE'':A@,'1/-D,)>.?$21DE!H.+D>'(E/>);?F.B9>049%4+.*&&A1)1+1/(79F%+(G=DF!H$/+GA%,?&7D82?F&3G
@r832
CTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTG
+
>*669,=A2&+"HD7D4F9G.7C'<<CH6DE4E;('9%>?)BC'#!5)9!+;:B":
@r833
NTCTTGAGCAGGAGCAGACTTCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACG
+
'+!&)"&%)%"%"$*)'*""&&#(*'*&#*%#''+)*&"!*#(&%"!$*$"(*'''!+%)"("!!#*)(#''*%**')$'%+!)"'
@r834
AGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCC
+
3.%)C'F+3A#&6<,1C/A-HA$D.?'F)4H#41E8E=H45)<+=9>14
@r835
TAATGAAATTATTTCTAACATTTATCTGCATCATACCTTACGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTA
+
9:6;=$>5!',/%0H5F-3C>7H!2BE7@<576<1+;#;5#G*84#:'=9=3/4D3C#6;49#(86>@5;;/!;2E;)(!93G*A*;?<&6%'/H45@8</
@r836
CTCGCGCAGCAACATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGC
+
E%C<.02@2C<H-@F49@1$/<)>#;;&1<6(&9/82D'6!A'H2?1F0<;@3@B'<%,?6:8/$A3.:D
@r837
GAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAANACTCGCCTTAAAGCCCCGCAGATACTGGATTAAACAAGCCCAACATGCCGTAAACGCCTTCNTCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGC
+
$&B/>#'37;(*%#A9.B$4&A(!8*4?8/C%1?+C@'0(2;.'B3+F4AB:>4#753$%4!;35/-?%1!#H;;C2!H3&A'')0+?$8@95?9,*D:')C#!0-B)%&.:F),(>4!GBF(#$"GDBD3/A>='7EA6
@r838
ATGAGCAAATGATGATTGATTGCTTANCAGAGCGTNGAAACGNTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGANTACGACAAAG
+
06)"$+637)$B/=+F"'E0H'0-@9).:'9+"'!1.6=0:5%%,;??,/?/,G65;E=+?G"H:C#99#$)'":EH:$<?(D))&<=6;66$:G/+16
@r839
ACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGT
+
=GG$93@>,A:$&B=/(GG2$@$,6#4"63=6#/,0G2#*#43?&86>8$53ABE51*@8)%&G;,8%,9$
@r840
TTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAG
+
$6-:?.!@#"85#;<)E*?C&'"D=7>$28#'/C!91!'!!D95@45;H4A3
@r841
GACAACTTCNGGTCCGGTANCGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCCTGACAGCCAGCAAACCAAAACTCGACCTGACAAACACAGACT
+
'#.*3G70$86$#A=(/>:5"(0=)='#;%:.%952B.0)-?(F(ED?'5=A33E13%#-&$8-58!+*)B"+"#'%&<(*@@G)*245@1<@1($+(*.G2,8;5/=;DE"1+F!'B.98*3+H4*>C.F"2<4#
@r842
GGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCC
+
H?/>H?(;!.H4G$C&D:)#B,8@=6D;.&H)'-GH/#)D?;!96A+3H7=(C":<D2,-79-:B3!C/"7A0
@r843
CTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATATGAATNATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTAAAATATAT
+
47"=2=9+.G772HB'%C1)+8:>50"/@)<C!GHG)A+"2+F$3/,(;CE2$%*;#@9@:>+B;.*2&B@='D'EB/7=*0E6105)5*-2:)&1&#0F?=C:&<H1&7<(#@?5'"8(%F,9'5@>,?G!8;F!%7H#A617B,>.'542A%F-=*?,(B06E/'>H*61C%"9B)#%001$4697.G6@>/91((BCD63?;B'4;6*8C4E)0<',,A#A&<$(!3!?E6-@"@/3'9>'2:7>A>)@/9H<$'1+5>8EAC/6/*F).+H%0/'';9;:
@r844
GCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCC
+
38EE2>2E+'AE<@(21=B!="*7C>%87@5H2B2)!.>$H@->6G8=61&
@r845
AATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAANATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGNTGCGCAGTTTGTCTGCAAGACT
+
,"<.08E.=F<H&0A/'1*!<%?2&;5*--;5?+!BD="8C%E"A!4#*,,3BB?7=<%@79@@*0B5'>>949EG!C88($)412$@CAD-B.=>DDH7G/--0$/:28'512B''ED'DE,&6"A+-(#2E?,D1=7=6D*$+)>*+8,1'!3=!=:3>3=%E4<2<4$">#3<F5,/!&:2(1'2%+:'*/H3";=:A?5?CDA5$+&HEB")=8G#,C&DE+>GE;"C6&=*4++"+,'7>D",<9'.;>=9@67,:B.+9D%;9><.+AE'F;=5/+)9EH!E")0.FA7-#7<8
@r846
CGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTNTTTCTGGCATCTTCAAGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAA
+
?HB&4>6"#2E5:F0((&=7!07C.H;E+.@0H;.'&89B,63&>C!('/0558-"+%0*?)-"'HCD*>%F"44'"D"&;E!$A$35?G!$9#+D&4)2"507&5D&;B*!;<+61?2GH#$D?@E39C
@r847
TAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTNAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGG
+
GE;+7"2/;/8>%.@+)&""/F6*G!9*-&6$GBDD)1&,%-1:>&A/(.1!4,8;B*59H<*3@>B90*32%2EB!!F,<//3E=?/C38.*,7E6)!0/?/4"$7/5+(4B2)*4-++?C.6?1"?-3;46AA5@A.1D6&F:.,83;-04(7#2',H&#=&,9'&<=A&A<G5%6?#4,<3:FA;/4(B
@r848
TCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCANTTCATTTCGCATAAATNACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATANATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTG
+
F$4C4@8$D=$+'C%&>@C3"BF1.":*7&*#==0F@6%8-%,!D<&H6-&9%B';.,=-4%1,%G#>)1&C)??F#>*@:*7-8-!,574F/!972><+&9A"-(0D29?"=;95'<;:04+72A9.FB3>(.&A;#34**A;:#)'E&0%0:7,";;<,-(3%AA(%##7)$2(,/"6G&%,@+);>#-@66=",#2<1*+>%7-#?E*?EF3CC>B,46H@!FB%0B?
@r849
ATTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGG
+
-.8F58>"#2G<2&#02E)/:4+,..C1DE&+9!+7H*CF"A63"D(7A&4D,"E>/D*B9>666D?,:$A(423!9!?8A
@r850
TCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGACATTCCCCTCCCGGCGATAACCAGGTANAATTTTCCGGT
+
5>D7&B.H.G.50+?)F:C8C9'&$9;3>28''#A8=F4)C27GD=C1-/33=3H8!)B/9-B-6-$@="<153&C!!6#!(326=(GH;09#H*9*B?)@'47.77CHGB></
@r851
NTTGCAANGCCACGGGGCCAGCAAAAAATCCNTTATCCGTGCGTTTGATGACGATGNT
+
&:$E@"3"1(?,*$6B(/!#/22ED@A$;4#AF:">;@C2-G;(>5B#45FF/BB-4D
@r852
CACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGNTGCGGCCTTTTACACATGACCTTCGTGAAANCGGGTGGCAGGAGGTCGCGCTAACAACCTCCNGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGA
+
(G;34E-,H#A%9=$EB2*E(;?51BC2!++C(2%<3@#91(6E<=B:>3$&;,D'G1!07+5>H;@:99+4#2#+C&7-"E"2:*$9.';H35/A9E0?+$$1#G@8=*C-91D)4'1#HF:&#?=::8;$G0'G'?:6&'*A=.3.)'91?6+<DG/=A
@r853
GCNAACGNANGNNNCNGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCT
+
&'"#$'&!*!$!!$%#+"$))*+")%)&!)'$$)""%$*&''#!'"#((&!"##&()"""!)
@r854
ATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTA
+
3H73=2++%63AD&!(*A,6!F5%@A.%&,/C9&=@B4H;F'+D7F7$3)*(&*#@HCB?#1'!.B"*H%"@;G)1A;8)=3
@r855
NATAAATAACCCCGCTCTTACACATTCCAGCCCTGANAATCAAATTAAACCACACCNAT
+
"B")-+DFC20B!'55A15"88D5%G2E#1&=02C()(2!7@%1@@$#50:$D7163C4
@r856
NATTTCTGGGCGCGAACANTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATNGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATANCGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTNTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTTCACGGCACGNGCCAGTGCG
+
!(++$*$+&%+&*&'*%*++(''(%'')'$"#%*!&'#*!$!&*##*%#"&*#!'$$&"%%(%*")"!&++(#&!$%+!*(#(&(%(%&('#%'!)!""*$+$!"$$&#("!%&)""!#)+""""$'#%%'')%+$!$"")+#"#!!*!#"&+&!)"!$*&$#$*)!$!&&*'$%%+$$($!%'!*!#!$+++!*!!**(#**)**+!#$(("'%%(#&&'+)%)))&*$((&"##$!+&*"!#&!"&)"#%%)&"+%""&!"*)*&&!"$!%%$''+++++"#(&&
@r857
TGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATNACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTG
+
9'6;2EG:>H7&@B42'/A:15%A):#=ED7/'7H*59C"-'C9!$9F+$./.53(3+?!8BB/3"G=0/F!A"0'(/786F11E9)03056/6FD'D"F(=%=<%7%HA#(DF:!(G4/;D5$=FA,-.91@CFD<#$6%6?<B@G?F8:A&G
@r858
GCNNNNAAAATNCNANNNNNTGAANGGAANCTNANTCNTNANCGNNNANCTNATCTGTCNGNNNNANNCAGNNCACTGNNNNNAGNNTCAATNNCNNNNNNNNNNCAAANCNGCACNGNNNANGNNGNTGNACGCTNNNAGNAGNNGNNGTNNNATATNN
+
$""""$#$"$#"$#"#$$!#$#!!!!#$$""!"#"!!#!"$!"!!#"###$"$"$""!!$!#!!$!!!$###!$$$"#""!##!""!$"#"!""##!"$#!#"#!$!$!#"!##$$!##$#$#"!"!#""#$$#$##!"!#!$!###$$$!""!$#!!!"
@r859
AGAGGGAAGTCATGAAAAAACTAACCTTTGAANTTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAANC
+
0E#<$0<9B>/#<E7*;)-88.)D2.?F/-EF8F5E(0!'E)%A-<::%>7":E?."%$+#':115.'@#=,/A92$5,62<<'E8FH'&2%1>6';/
@r860
CATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTC
+
8H<E7%*H@#34B%9H<9$D7).E30*2A8!".-56$&4%<4,AD)0"-&#H5A'<784GE>E"EH)'0.G/C$-2!
@r861
NTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTNATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCG
+
!*%())+''((('#!%")$%$+%#'#'*'##+!%!"&(*&)#&%'(*&+"*"*#(%%%&#$%'$!!(%'*)#+)($+#(*(+
@r862
GATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTAT
+
<4)DB<'B"G47"'8-11&G*H#@5B2(+<0@&9=G=/8&@D;$91>E=99)1D6*:$A@>9<'<.DCDBE*69"7H(-*2=#/;E
@r863
NNGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCANTGATTACGACTGGAAAGCATCNATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACT
+
%#+&'''+$$!)#!#)+(+)#+((!(!!$'&%!*%!$"!+)$$+!'"(+!*)*"+')%**'+%+#"'""&)*%+'$#&%*+&$%**++!)++#&%("*'*)!$&#$)!!*&*!&(**%'+()!('+&%")"'$%"#+'')
@r864
GCACAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATT
+
658HC?@*-@3'<44*ED&3493G2H89:A>+B(E6(GB2
@r865
GCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGNAGGAACGGAACAGCGCCCA
+
"5.(2!.-7+1@&G$4$0',C=5/H9(E(/&BD)3/$:::9>$D;4&5?%@(7*-3%:+E*!B1&"0"01
@r866
CCCGTTTTCCCGAAAAGCCAGAACNCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGC
+
5:A7F-A?8B2&56&D">H53*2:-:6<;.E9@E>&(>1?,6D+G/"67-1%D395"/.7EB>0.95678?<">
@r867
TGACGCTTTCGTGGCCGCGGTGGAGGCNGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTGTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCNCTTCT
+
@"8*3+H(?5A977.?BG+/+9%)&A7<1D;57?+F=,($/3%?H?30+.")&3.8-6;7.*1C>$%:07D@'!70>)*A45+GB?'",*9D':4$@6$""%.D@ED%5A<F'FBF'?5,(FH;,</E--A79=/>>BB$H:G/?<GA*/E!.84%GF$.FE*.%?-<*89!
@r868
TNNAAGGATCAAATGCACNAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATAT
+
$!'+*((%!+((&&")"))'""$*$%)*!)+)+(&#)%)#()%&!#+%*$'*+!+#$)))'('($!$!&')*)+#*##"'"'$)&*++&*)+#)$#"%!((
@r869
CAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACA
+
:(E8%>0;(C&*@G>B+"-?-8-7/@*05!+;@">C=?,'0!<(H.2"F%51<<9F3GF%.5CE4=8<"#)F
@r870
CGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTTGGCGTTG
+
6C%2B3/C$$6>=:<1?/7-!*B%D@4?='"2--@.8@FGG=?)7AE&;@C-"EE7"F-E%3'5>:@=F;.''?+=H*C>BG&44(*<(./->+),B%8:H;")%:304B8A>E",:!H
@r871
TGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTC
+
GG!%.&*1>H@1=3C&%FG&#CDD;-)9"5!$H8=8<?;%**D3?(<4CE56/)<!+E$DA8B%89@8A,;EC;;/$</7D.0"-C31+A)
@r872
AGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGAC
+
F$!EC#8"HG';?!CG(<:*:04@BE=,F5!H(&13#>2>;12C!/!(3?*2:H$:<')1/@H>:B1-2,$$?5HC1<"F$5D
@r873
AGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTANCGGTAAGGCGGTGACGGC
+
@8:@?$6-,G1%129:7>+2(=<E4%2+:D@)-%3D7C<26?#.8<*#E%606%<-'"+1,%==#<:CB)<F2ECCEEE-F$(!)!:',?H)'$!8/4#G&.<4?+3GF,691+9*3?6'D-0E<C"1/G@+(4C"@-1.>EC#,)08"13.5&#'=1
@r874
TACNGANNCNNGGTGNGATANACGTNACCATGTCAAACCTC
+
)"'!*&#!'#'%$'##$&(%#"&"$&&!&&*$+##%''&&)
@r875
TGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAG
+
F.5G,;?B((%<!E)/8*#?AGB#7#;'-<@?-&3+HH174
@r876
GTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGG
+
C5>**$,;B##!FC?'$1*)=4A4;#+57"7#,/"8*(5+'
@r877
CCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAGATCCCCGCTTTCTGTGCAGCCA
+
)(9A*>3:<5(<%?4#0&%A&126#F18:H'(<(4%44%!.5,+#)1+A6>*)&G0)A47%/F/2<,0GD+/<B0A.'-5C47*4/G!+$4"@-2@!/C';HG09'F(9,'A8018+?@%)GF@7&'F@*C+38$*
@r878
TTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCAGG
+
%@,E7+:3/01;0,'%@A9=?3/)-*-GG,?&*))'D4G.
@r879
NNGANTGNAANATNNNTNTCGGNTNCNGGNCAGNGNNNNCNANGAANNNNNTNAANNNN
+
$"##!#$$#$$"!#!"$""##$$"!##!$""""$"#!#"$$!!$#!#!"!"!"""#"!#
@r880
TAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACT
+
E9'H+%$B"$10?G2;43())11!BD>#-+EA)+$8>G$#*A&%)4.A>B%
@r881
ACGCANGCTCTCATAGTGAAACGTATCNTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACNCCCACACTGTCCGTCAGCTCATAACGGTACTTCNCGTTAATCNCTTTCAGATGACTCACACCGGTATCCCCGCNCGACAGC
+
?-2=->=3;4*1*/F&>?-C;".G1-:,A)E0,.C<D7#(!8")(>@6$:C)/55!F*#0(,-F+#5G+#;-',+/D,D7%C+EH<6&'#%/%5&&'?<:1:>$F:=+)62+19,0*4+.#9B(!#,AH,--=D-,E>7">;D-1*$+G)&*C).8%3*B:#'9G1?-,
@r882
TCTGCATGGAGNCAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTNCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGA
+
&8"FF3*5D<''EG2*"/6E;%$4F==5F+8AE3GC=09B/"FD#98%EA*C.1FCF3'=CD/7C-:<!B0(>213.;>+.65.D(.7054(8?+B:G9.6H#!9=>&7@'#1G7*E<9-+?C,..GB#39$;&7"$:!$C'/1/?++#G;1*:1B(==B,0=3;;(A(+A9"&*>&9./;+H@<@>/$C33)(%/.$-345-?<!H79414=>D22E#HG+#6#?"3'4DF%
@r883
GCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGT
+
*(+#)*&+("((*)*+*(%)'+#*'''&(*&$'!!%(($%*""(+&
@r884
GCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGTTGANTNTGTCTNCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGG
+
;6E=G15%3;((HH10@>C6"/$=C.9$>;F>C.+9C".0#G9"77@68:)<+HG-%,../!8.6H&CC%!HB3F:3A:'(E(8B):<6B*,'7H!@$75H=G:%<BE?-BD3#<23E!:1AB1+(G@3C%(+1*%67@>+57C-*$62)49->9-36))0(33$#E+$86@'C,HG<((%E?+99#/-
@r885
AGGCAGGGAANCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTA
+
E11F#@!0@8>>.#A)F'D6!4+A''CDF:8$-.%"30&<9;7D):,1,B
@r886
CATNGNANANAGGNNNNCGANNNNCNACTNNACATNNTGTG
+
!""!$"!"$!##$"""!$$#$!!""!!""""$$#$#!#$$$
@r887
TGNNGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCA
+
!#&+#"*&%'+$"!&)$&+!")*'*('"#"'(+'!"")%##!(+#+&+#(%!"%+%++&(""**!("!"&(
@r888
CTTGGCGGAGAAACCATAATNGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTA
+
E"+D/D7B>>@&F=6<>>--4?+':79>#!""=$8B1;F39(#(F%%D9/1-20==*:*4
@r889
ATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAA
+
D=;:;%0D*4#CD)C6A=:+*(1!&G.9$&+E%=G11G).=B#%H?8A=/75H=2G-5262)>30#F0F"=BD@4@
@r890
CTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTNTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAA
+
$)++)!#'"%"%'#'#+$)###!+&)***(++$#)%'*&(#*"##(#'"(')&'(''#+'*#"%!&"+%$(((#&+&"%(+")+"#!#"+'"+'#)()!*&&(&"(*#'%#%"!$%&$##%)(!("'!#&!+'#((!'$
@r891
AACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGG
+
(D)?1H"F:248.&8--7F86C6("9%)<<(*!";*A46965;)7@A9.*>5D%G,H@-3;=>32/#$2<%7/HB!/5,84-CC,BFA&F>C3CH
@r892
CCATCNCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAANGAATAAGTGCTTACTTCTTCTTTT
+
7<<6:%CG92.<A?:<-->H.52H$!?AB;:H,3'9/C0%(;#1!C9?F#3C9-!@:!.-59"3G-$+@)D<;F.%933(*,8**6,334=0:8%A'&*75!'-..'=2"=24G++//66
@r893
GTCTTTACCTNCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAA
+
H5)$:D)2#5#4)&"+#H&6!BEBE*;*#E.&:D;4#-1?5;EAE@'E@53D#!-?+727(H!*252?G=%/$8C)61D#>#5(>$7*A.?E&--7&0F="(.C!@,'$A<1=3E13.5A$+:BF0245%A.7D=89($,=5B%$=HE<)8#?*E%C(*7,C8C:=!"&?;1B(473EA.EH+)4.9+
@r894
TCTTTTCTTTCACGACTTCCNCACACCCAGCATNCATACCTTTCTGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAA
+
+*!'(+#)*&"&)%$!+*'!(*"'!)%)&&%)"*(')%!!))'+%&!$&%#$!+!#*$*())$&$+*)!*+&#!!"(!'(*%&'*+%#((+$(!!&"+(")%*$$
@r895
AAANTANGANGATATNTNGANGACNNTTNTCANGNGNNNGANNAACANNCGNANTAGNNACNNCACNTNTNNTTNTNCNGGCNNNAAGNNAANNNCNGATGANNGNNACAAATGCNCNGANCANNTTNANNNATNNCNTNCNNNNGAAANNNANNCTNNCTNCCNNGGTANNANNNAAGAAGCACTTCCTNNAATNNNNNNNGNTNTAAANTNCNNCNANGTGNTCNTGNTNNGTGCNTCTANGNNTGCTANCGNGGNGGNGNNTCAGNTNGNNNAGNCNNCNTGNNTGGNNCNATNNACGNGGGCNNCTTNNANANNCTNGATNNNCNTAANANNTCTNCNANNNACACTCCTNNCCACNNTNAATNGCNGTNNNTNNTGNNANTCCNAANNNTNCNNNCGNNNGNNTGNNCNNANNGAGNNNAN
+
##""##!#$##$$"#!$"#$$$$"$"!$"#!$"$!$""$$"$$$##$#"#!$$#!"!!!$#!##$##""""!#$$#!#!$"$#$"$"#!$$$!""#$#"#$!$$"!!$#!#$$$!""!""!#!"!#$##""#$!##!$#$!##!"#$!""$##!"!!"$"$""!"$"!"#"!##!"$$##"#!!"""#"$!$$"#!$!!#"###!!##"$"!!"!!!##!#!$!""##!!!$#!!!$#!$"#$$!!##$!#$$""#!!##$"""#$#!"!""!"$#"###!$#"####"!"##$#"$!"#!!#####!$#$!"#!#$!#"#"#$#"#!!"$!##"!!"#!!!!!##$!$!$##!""###"#!!!"$$$"$"##""!!!!"$$##!$#$!"$$"#"$$!!"!"!""!!""#!!$"#$!$#"!!!$#!
@r896
GGGAAACGTGATCCTGACCCTGTTCACGCTTACGTCCACACGGCAT
+
2CF.("3D"+>2!F)%73!9341.+@!#?%;*=<G)!3!44?.#;*
@r897
AAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGCAGCGA
+
+F@--0;C)/18$&(G"E35/E&",.)-?8B0>>(%B-H:1E8E4*F.+#E0)#**@8"BE2E%.?;19
@r898
TGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAG
+
4G+(-G$C"C:9&)F9)$D'>)4!#;96H#D03D1C(#A:)-E)-0)7D/":CHB
@r899
TGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGG
+
2=>A;$/&GC:B9/;,;-+<E$>$6'&<'#9>+B%1H.#?F
@r900
NNNCATNANCANCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGG
+
!!*%('#(""##%#+#))%%%$'#"("!+&&)')")!#&*''*!#&*$(+#))&&)''*'+%()+(''&!+&%)))((!*%#!*%&%(&$+'""+&%%(*!$""'&&#'%'+$%(!)#)""#)$*'%)+(+$'(&)'&+)))!)+"))*(!$%#(++%)%!"&"&*""%*!*""!!%!#%'(*
@r901
TTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCT
+
3DG%1B0;#043/+C-7:2(+!4%H+C,4)+)?&G.5D5!3A6G$&'(
@r902
CAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACG
+
*9<AA6,#1%07+B6)H8",A2%A1B=CA?:745.(1;("0;/"!1&!FG0+4
@r903
AGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCANCGGCGGTTATGTCGGTA
+
D,-@G)E<?EE//"&@E+.?<2+.556!10B;78':D%/2!&14+1B;&F?*C()2@3.8;-%'"+/5G6@>,,<0/.
@r904
GTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATA
+
">)1'!,B%@=)$(-7"&B$;<**=1$:&A=&1$-';1E1=@5)E9FG!D(CGF?+=/D#521=1
@r905
TGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGAGACGGCGGCGGTAAGCCGGGTCCGCNAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCNTGACATATCCCGGCGTAAATTCAGAGNTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATNNGCGAATCGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAG
+
D',;2"8<:A>4)C>B9&2A7F.9-&0C=284;D7EB-"<G=.9$=+:;E8+->>=-)-.+H+)'=B>1845&+4GH#C5>6/"(,=+6#)-+(+>9-$!:!D?<6F048)D0=A080B!9C""EB$<6F>:D2/9-$>A@-9D@?.@F-$=31<!H/%C)7=,>.C"E5HB#A95C>@7$4@GB0.!.H(%.4F67)@2>'%509<G3G:10,8:)=F5+F-<!0F3,(,8HD6#=%H0*1&9$G>6/;F,*=626B#G5E;C6BB"2?@,8>4F1++")@*95B+1>-8%
@r906
TNNTNTNNCCCGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCTTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCTATCACCCCCACACTGTCCGTCAGCTCATAACGCTACNTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTNCGGCAAAGACAGCAACGGCAATACACACATTACGCNTCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTNTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACNTCGCTGGNAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGNGAACAGGGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATANGGGAGAACACCTGTACCGCCTCGNTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTTCAGATNACACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCAATATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACTGAGAGTCCCGGAGTTCG
+
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
@r907
NCTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTACCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGC
+
!D?6@50H3<6)6>=0(G-55!GD+@>8?5,E03:GC-+?,#':..2&!<:B54BH/=6GE/-=&C"&.&71-G8275!5.>325-"@8",=+3143)8"#&C3*;G
@r908
ATCNGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAANGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCT
+
,)<6-366#F?(>B,F;,$65++@=:>B+7(E%*-9!;"'5E(<%9E593G1A;,#E:1=.21$*5:"8//CBD4DDB+12:>=&6?F4!9*$G:<(+-
@r909
NCCGTCTGGCGAAGAGTGGNGATCAGTTCCTGTGGGTCGACATAA
+
%&,)C<*G%?C<)--8HB&++B"AHC@F*4=-%!+HE<='.=E/2
@r910
GCCCGAAAGAAGGCNGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAA
+
31'$E(+#H*:#%1D;4<2%+#>5.?77"0@/1D"3?G29"#BC%!"@12D@C69&1@7+4*/">2A:::!(('H/HH;<
@r911
ATACAGGCCAACATTGAGTTATTTTCAGGACACAAACANAAGCC
+
4)->$CF286-?H?285/1@%-.=:$'7'H4050145%,&&E5(
@r912
ACGCGNCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCA
+
-6$)7#%#5&.$A>H/@E#3F:;4:'#5F,&;E>"1(72E?);
@r913
AAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCA
+
3,"2'AD4B-8#8".?/(.4E#18#"5*522&0HEA+F@<4$B.;*?#.3G;!,663
@r914
ACNGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGNACAATGGA
+
+(%(&)+%'#%'*!+'()$*+$%*)"(*++$&%'"&&"$"(%)((++")*'##*%%"+#+"&(('##'$""$&&*&")#!(")(
@r915
CGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCNAACGCGCNCTACTGGCTGGTTACCAACCTGCATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGCCTGCGAGAATTAACCGTGGTGAGGCGA
+
$D('H0?.'<"5/+<CBEB6A6E@9>(=G5C<.*=++.+B5,5?C)<.,;,8C,E%G5:,-<56$/E@*6112,"-2,$<$#B5#)%&B0C,#'$<&))GH3!D;@<1(":0"&A?69)5A/9B*(@"=&#8":B<)31%345A!2G43G3HH/'C,#<+2A=6=/"*!G$>8'B?/#8;?2$9"49?<CD/-H@(:>7%=6#&.(-:6CG>EGD:F&5>+2GB%@>
@r916
CGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCT
+
D,D=,4*"?'/,+?,.8?9%$GD)HC6A)$-)E$F-&#/9.,1%+83%E/4+:1D5/DG+0C0'<3$C2<6$:6B2%F>D&F;1G3'F#0$H
@r917
CGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGNAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATG
+
,&'?:=57FF,*>9)?93:54=.$1$F+-$.E0F=G:?94:!-%4E;?0A9C@HGB4,/G,(!->1&)B.'EB)E"<+6?)+#&2+>"%3.%+,%$3:!H6==A='D?#*:5/%1?:><A89%F&$;??2
@r918
GAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGG
+
FDH#A@!E=,2@@:$F4="A=,:C7A&H?,&>-DB*!85&3G991D>FE5%=E:$(*,*<A29E*B:FG<%!E;(+:.3%')#1
@r919
TTCGTCGCGATAGATGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTT
+
+!#)$**#*"+&$(*#"")#&+#)($!+"("*#!)$#(*#)!"*%*%+#%!+)(+&%%%*&%(*"##(()+)(!"+$((&(!%$**'$
@r920
AAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGT
+
F',$<FF&*31#/+-6")1H04+-#85A/F:1?@:E+9/=%D891#>0?A+=5=D1"6H(*@-G*&"?,,975@:>(>7/A2F8*H##5.&G:8,*#,>'<+'F!H<$+#CF5F0)F)H>74G!H+E"GB
@r921
ANNNANAAACNAACCATGTCGCTGCCACTCGCGCAGCAAAATC
+
((##%##'()"&+''(!!!+&('(!(#!+%"++()$&*$)'!"
@r922
GAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCNTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGT
+
+BA'8<%0::A5E<0$/9"D3-5;H944-6"(/."6';FE8--6,F?3!+A%-#=?D0+HDG60D!A01,'4&=C>620+2*B/+3,+0C'/D9!:058#8&1"&A5/;0
@r923
AGTGTGATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGNCGGTGCNGGACACNGAGGGGAAT
+
?A?(%!?C%6;ED=H1=%9)6<99(.&8.B1*;B'.'@@-%8//>32!*7,>-3@E&F-6*E.<084ACG,$?2/C=**G<<@9G<A+C>E-9<B=>9"3&;G
@r924
CCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCC
+
D<>"5!85>4&E<1+2"*3AE).47/=E/:73D!?*;<G&A$B'&C*EC:;A<7--A.-&73:
@r925
GCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGC
+
'2<C=61);?.,%$G'DBB#:D>D:0;H3#E+;">9F/A>=@G,
@r926
CCCAGCAAAATTCCGTTTTCTGGCTGATGGTGCGATAGTCT
+
B$"B51"(#<*=7FD,FH")3!G-@!G/EGC59!2#*6<&*
@r927
TCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGG
+
C,@#.4HB?-+==*#9&"H=+*1&$%.++D5,.*9DC;G/2#E;>/#45=B$-:73$9DA:&1(H>F<90+9*331!D0,
@r928
NNNANNNNNNNAGGANNNGNGGNNTACGNNNNTNCGNAANNANGCNCNAACAANANNTCNTNNGACTNGGNTNGGNCANCTGNAGNTAGNGANNNTTAATGNNNGCNNGNTAATTCNNGNCNNAGTGNCNTGNGNNNCANNTACGNCNCGNNNGGNCTNNNAAGNNTTGGNNAACGGTATNGTNNCNT
+
!!!"#$!#"#$!###!$!#!!#"!!#"$""!""!#"$#!$"!!!!#"#!"#!$$""""!"!"!!#$!"#!$$!###$"#""#!!#!#"#"#$#"!#$""""!"!$""!$!$$"!#"!""!$$#$$!#"#$!$##$#$!$!!!"#""!$###!!!!!$!!$""!#$"$#!$!"#"$$$#$$#$!"#$"!
@r929
CGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCACCAGCGGTGCTGACTGAATCATGGTGAAC
+
>H!0:C"669=<+;C(F,B;0F=@#FF:,*9F42$+1A$$5?B+;22GB+<?/<>020CG65D4=1B@1$*C-F4-/<",(G=-C818#
@r930
TCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGA
+
C;$,#4HC.,"4>.C=>=@293AB5'(E'9@'E;-/4"'&/(1>G&$#C=1#569B$65D/0-=.5!5>7A.E("'F@9>(7"?<'4!<6%*4"3#6!C(#**1:"C6>#87*;'2DD9
@r931
TATGTTTTGTACAGAGAGGGCAAGTACCGTTTNCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTT
+
818G%53F6>")7=0-,8H1B=#5E;B-3*6@3)<%),+;#!F#<C?:<B@34D-C08AC)<>'B&H84B7AE.;
@r932
AGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGN
+
:0614B/(@1>646"!,GD+&4!3<01E33(.>/2A;C!($.,&9
@r933
ACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTAC
+
*4B$-#E69>D/1+)+930)%%2+,A%80,$=9A8C<AG;>;79-21G*.@@GD.;,);)4849;A<<74F"!,.=0B<@(8
@r934
TGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTG
+
=FF'*'<43,;56*-?4:$&7(,*:2@CEDBEC8'#$1@57.3'23&H'-;-7!???076#-E&5<$,"@A
@r935
GACTNNNNGNNNNANTCNAAANGNNNTNGAGNANNNNTCAACNTATTNTGNGNNAGCAANNATANCANCCNGGNNNGCNNNTNNCATNCCNACNGNNNANANTCCGCCTNNNTCTNCNGNACNCGCNNGNNNTCCCNGTCTNCNNNATGANNCNTCNNGNCGANNTACNNCNNANCCNGANCCANNA
+
#$$$$$!$"!!$"""$##$!!#$!$$"!!!"#""!!#$"!#!$"!"$###!!""$"!#$$"#####$!#""#!!"!$#"#"$!#!$###$"##!"!#"$"$!$""$"#$#!##$$"#!#"#$"#$$$$$"!"!#$"!####"$#!"####$!#$"$"#$!"$"""$!!!$$#$#!$!"!#""$#!!"
@r936
TATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAATAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATG
+
04@HE)5:/6:D&8@5&)=).?@>G5$:&63-#C28"36)5###B!G:'*'.8.!#(98;A"++-"%-2*5!7#-7B>3#0+5,@(E%$:/#./8";/<9*,',9D@=5"%1H*(AA0''(@DC'%$856H5/$,3(!(D1DE'3&'1,:.F27D4#4!$)*8'&#<';60@C7!6(G=E;1&G;8H68H)7>,+9,E.6
@r937
CTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGANTCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAAT
+
0(,=6800,)=C5:2@57&H2;@,@@5.-<(2AC)A@'!EE1,'1&:+-C'<8D'%H81G"F:&;($#%A%;9004H*+1&#%#1@B>FD3'9B,+'6;HAC#65=,;@
@r938
CATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGAT
+
(/!#6052164F+4(+"DH%8*7+!4>>A>DB#>2AC)8C;#@@"GG2'8(A.&8)B19+BA.$F?:$7>3,<4:(E.*2#+8,1+5=$-H*+A!G4D"G!&/C+1C87D<B:B!D3>%+;E2$$B')2<#D&&02=AF'+G!#GF60/*<.?%))?!"10A,F%E53
@r939
CCACTAAACCCACAGTACCCAATGATCCCNGNCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTATCGCTANTCAGTGGCCTG
+
DA@>E0-,)6/?8G6A5C/?F=@>GH;8>F*?=49./G?H>G*$8'0F:@2;%)E;E+!".3,:9.&)9#E?9?H7G%;D?-
@r940
NCTTNNTNATTCCCGAGCCCTGCGGCCAGTTCATTCAGCGTNTTCAGTGNGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGNCAGTACAAAAGCGGTGTTCG
+
!*(!"$#"(*+*##$#"%$'*'*'"%!&"($++"%%#*&#+(#)!$&!&*#*!#*#*)*$#*"!&*&"$%#"("##'#'($$%")$!#+(#)'$'"+)++%+!#+&
@r941
NNCANNCGGGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTC
+
"))##*%&$+'$$''""%!*()'$&)!%#+#+&%&*)%'$)+&%*!"&&#)+*!)%+)&*#&!&&)#+")##$#%)$'!""'#!#%&"'$##$(+"
@r942
ACGCACGTTGTNATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGAC
+
710$'43A98F*07G-"7;/*B%*GG7G%$'74"8"5%8%.,F)1A/.4G??94*B<&BD--G=
@r943
CTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACT
+
D??)%@14&,=GG<697$D+9#C)1'';CE3(6!<!@0@9,>%,/6=+!!H0#5-FH1!93EBH'.#:6A3H1@)="DC!"7H,)/!9D!!&8C6<+$E0:=D>0#:-/<A9*1$>@>,DB0B&)-52+>5=$'"GD1H1?/:'2:D/;';2@B'@>&>
@r944
TGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTG
+
65@@55>7-.<:;F,E/F+<=16(4?3C277@--B*%>G&;>C-3#F044:46E6H&'F*6C#5+5=1!=5?!;8:(2)"#<1=ED>
@r945
GTNNANGGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCANGTCGANGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGTTATGGGCCGCAGTGAGGANAATAACATCACGCA
+
()""''$$'+%)"!'%")'&&'""!&'++#'$+*)($(&)'#(!*!'(!'&+("#$&(&"%(%''+$")+($)*#&(&"$%+!&++*"")""*'*+)!)%(+&'%"$('*&$(((((#''%)(("&%#*$($**+)'#&+%("+$$$'&#*'%&)"*+$)""!+#'+%*!()$+%$#)&
@r946
AAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCC
+
=?0#D:E3@3/@GBB9D2EH-7*,765D;G1!2<D>>"50B)+-EG=5B0+<>/4=/A(HF51B'+B=@E%
@r947
GTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAG
+
9;%B*2++G7/<6H3>FEDH;(*@#<F7$A+4D&%C-4"(6?+#6,:<)CGH1*:A*?3!7(?7/1(#*"E>B)BC*%HE7?=>C$3'>((;D6%G>"8:(H"#=07CF),"$$.D+(;>"6'H<*5EC;E$$,47&#/4*>H1:<2!*@%*EB-F.3B0(!===(2(
@r948
TCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCC
+
+?+,;:9!#@3<%74"!!,C05#D7G7>#'#"/0,>20!3A;A)("#6,+$=1=+D@*20F@
@r949
TTTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTC
+
("C..%+12C.)6<(/(?D/&3*+/B)!=%>928;/<-;7;7-H:+=:D!7=A?372B&((+7H'9/8)=+-<;CC#!&;%<E,/G><G,?3,!6)
@r950
NAAACGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGTTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAANTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCATGATTGAGCGGGATGAAAAGTACATAGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGANGCA
+
050*@@%F9E-4-A%=64;A#<;7G&)&-'0@E86*,-5;6'G:AC>/*1#!#G,@@C,6+,G!#;5'7$="*92)!/:B,7H(<131?!;=F4A+"E91G3>4D-*(0E9$C94!#:D+4&E!"-9H2)G:$6.G+BD*$C&);;((#4@"8#!D/29(85E:+B$)=79C=#647GE)E90G<*/D,A;%1F9-GD<5E"@A&3F(E7?>:"5A9'/67F;-8*(3EC;<@:=&F(*;7;#=8/#(C0
@r951
NAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGGCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAA
+
!9C);=>D)$;F@42#0.*&2G%6-!*4(6>H6.'+"H.*69-'$5H'B%<0&5D-@H3CB=;*-6$"+E4?EF>EB56D47E,7(&G<;'E)9!>#!;/.5A5&//:G?72DB07A0'>'2G+F7=F(-3=<&/8?1(!"H?&>
@r952
CTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGC
+
9)C=&%3H'(A"C,%38B,;5A'C;84)/"H5#?G6;:)"&@#+D
@r953
AGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAA
+
D'6%3='"0)(-4!.%?F=B.&,H?6$1/0=#C:.%1$1=5=+*2
@r954
GCAACCTCTTCCACCATCAGTTCAAGACGACGCAGCANCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGNGAAAATCGTTCAGCGTCNCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTNCACATCCATGCTGTGACGCCCGGCTTCATCCGGATTCTCNGAGCCCACCGTGTTCACCACCACCNTGG
+
#'#+)#'!$)%%&($$("#+))*"$*!(')%)&(+%#"$$"#&*$$!)%%"*"#**(#+('+#*'"$#*+*)##!!()+++#&"!*$$!+&#)*#!!")!%$"')(!$+'!%'"%('"$$%+"(#+*%)("%(((")'#""$**$%"!+($"%$$"('#+#(+)&%#+*+*$')#$+""$%)*!&"#)%#!")&%!&+('(*%+*%(#$#&)"$(!#('('*'+%&%+#+$&*&+("%")*)"#'*+'&(
@r955
GATGTTATTGAAANCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTG
+
$(+#!#*&'"(++#)&!!*&#!+*#!&(+$'++)+!%)"!+$$')"+)"&"&!'""*
@r956
GATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAANTGTGCTGACCGGACATGAAAATG
+
62;GEB&,<#"7B6,;&)43<?<#?1C'&!&&C$+$4*(H5664%/=574@GC=7717%@??6A
@r957
TCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCANATAGAATTAGAAGGTCGAACCATTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTC
+
+B&@#GFH25*2AF@$H-F46H'257%>A:%),CH(?E3*0=&H'47+F:$$*05:$D.29!+;D))BB80?.2A#&"-H751"<E344C6.0&8$DDC(C:0H?"!6/%726"G-*5:D$'@,E-/<??F*%;(H+H</3*<5@F;*2-FA&H.4)0.&1281<@?7&C"==8?(4A>,6+;(.&1@717G0
@r958
TCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCNCAAGGGTGCCCGTGATGAAATTCAGACACAGATNCGTGATGNTGGCCTGGTCTCCGGAGGTG
+
672&$/DD9*9&/9A<)96)<3$B')::%CF=@A#H7(#36A@1?)FF3ED%9G&.%G9&01:-(D<:=46#92'2&H>'8";8/,%!'-;E6(*55(5?A$(;<'8+1*2&EH8?CC78'+8>$45FCA>?DA4/>$;2**<5?;E6<51A"*60,1!+-1!"E0*0'/>(&+6@-HC#8E!8=@FCHE?$!2%.7/H?8&(,(,;7HG7<2C+>A9#B1C>0$2*#;&FG>,4;A(99DBG!01'*=2G9C#.7;?:8%G5)8+=6BH0#AG(5?<9'#.
@r959
CCGGACGTGCTGATGTCCCGCCCGGCAATCCGTACCTGATACCAGCNGTCGCTCAGTTTCTGAC
+
C=1<E2D%G=854H<9H?F>*$";7CD4;-D0/+!HF:%)6@FHG/$.!+B$<;0?!5()DH49
@r960
TGAACAAAACNTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATAC
+
;%1;*#<1H-A-G"+6B&.H7%;,E>7AF9?GD0AB/"<B$1".(B5/+&G->E/A$AE9'1?9-=<:C69?:+B)C)<>14.4D-.*,H-4;6-"/==*A9B!5:AC75@A,112:0C9(.,2;)!B+&,B#"+0?EB?&D??#B2B4B2:57E=+4>@:3"8,84@3"#4-4FD=<D3C&/7#45(H>H(050)'B-8B&E;,32E$6:8-4FC*8D.5E?5.;39?A/%9414C8
@r961
CCGANAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCA
+
#+(!!!!$#%#&!'&((%+#*$&%"#+!%!!&*$(&&)&)+!%+!$%!'"!#
@r962
GGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGG
+
0"&921*8B%C6B:)+AG...BF?>-E=:$.$F5!31?2+6**&(H;8*'
@r963
CCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTG
+
(B#3.9=<('791>+35%B>,58/1",</>8#-5!4!)..7BE!66(+02DH3?A=543>0>9*H?#!"'H/
@r964
CGGCGGTAAGCCGGGTCCGCCAGATTCTGCGNATCTTCATCCNGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATAT
+
7@?E,>)760B>&#,&F)&!.)BC%<&)>%,C)57%#(7$11.C;8,"D5:(>C!C834!&1(E>$E+@.F$?H/<G"'<7/2HD1D/>A+!*/4:
@r965
AAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGATCATTTGCCGCCAGCAGTTGGGCGGTTGTGTA
+
B5!6>16DG!F"A.'%F>4@;8'194*3#CHB>93?H*!HD.!6G1!$;G6&%6@D13()<B3,C8,16@<9(;.7G0
@r966
CAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTG
+
H.*F*CA-84%$"5!0AH0/#*1=+F.C+H&)*A"(0@C6C
@r967
AAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCC
+
%H!5.!;@!B+41AAD<!4C9%8?=399)<C:,H*?*C+(>&&+F'4H8485,3+
@r968
GNTACGGCGCTGTACTGGATAGCCGCCAGTATCAATNTCAAACCGGGCCATTATTATTACTTTTCTATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGNTGCTGGAAAAAGTCGAGCTGACGNAGGATAACGCNAGCAGACTGGAGGAGTTTTCGAAAGAGTNGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTNTGGCGCAGGGCAACCAGANATTCATGAACGACGTNTTCCTGAAGCGCCTGACGGCCCC
+
)++!")+)"%**)%+''"&)&'&*"+)%(&(&)!'%!%'!%'$!%!)'#)+!*#"!#$!)&&)#*)#)$*%"+*##''%"'$*%"!""#"#*!"'""+*)&+#(!#$%())"+%))'+*!$%'+'*)+!!')+''&))&+($#&('!)!%))#%()!*!""(*"&&%#&$$))*+$*$"(+*!%!'#%*'(('#%&+*(!()$%#'!*('))!'$(%'*%+)&+%!(%))(#*)!$'+$!%)!!)!#'+#*%*#&+#')$$$$!%+)*'"++)*)%")"%#""""%)&*#&$"$))"$!(*('''(+%$+"$%#++!)"$%)")"!!%$)&%!$*)#"+#)#&$(%!(&#+"($)!#+(!)&$!+*+%'$%&!+"&(#&$"#%'&(*+$#*(!$+*(*'#*+'"+'+("**(("'%'(''$%"!+#$(#%+&$($%")("$)+#%'##!"&+*&#$%'*&%'&+)"'(+'+%)'$#$#+(+$+!%+)(&&#)))'$"$%*%(&
@r969
TATAGAGCATAAACAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATNAAAACCCACGTTGAGCCGACTA
+
6<<.@?!"E&"E.*EHEC&")C6438&D&4,2B/26>;1%G8/+0=/=;6B3293D$=2@;G>;0$:G:1<'8@+9'@2*?'!=9=B>5
@r970
CATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATG
+
="?95%50EA2?43'EB(;/*",'/00:D9&H#6BFF9,2<'-?/6$"=BA3;8:D$&.6,AG8*8&5/<5+*+$;A"%33*;E0
@r971
CAAANGANCGANNCCTAGCGATTCAAACAGGTGNTGGGGCAGGCCTTTTTCCATGTCGTCTG
+
%#*)$$$!&'*'!*%"&)'+%'')$(!!*+"**$')!"+&"""#%!+"*''&%$(**&)($)
@r972
AGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTNAGGAAAGC
+
(*+*+'(%&'&$!+#'(!%'('#)'*#&$"+')*'%#))&%&#%
@r973
CGATCCGANAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCA
+
@:12:F2;0A).30,?*%4$-F+*<='7*)@>5D&,%5:F8C,C!=!G!0,E.5>
@r974
TCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATNCTATATATGCATTAATAGAC
+
C@%62/-.6G/?E+B$)@@!4$"H>E1-F.'($F8&6?@GA*"E&@A:/!",G<)+
@r975
CCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGNCTGTGG
+
$+(()*%'*"(+*(#)*"%!&#&"(#!&$!'$*"'+))$(!()''!*(+%"*#%)#+)!+#'&"('#)'($'"'+"%+*''
@r976
CTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTC
+
,A?,>',$5?/929*31?4%3+0G<56.>A,ABE6:)50B5;-;,AH4#FG=*>087HE03>DC
@r977
CACTGAATCCGGGAGCACTTTTTCTATTAAATGAACAGTGGNAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTTAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTNAATTTGCTGA
+
$E=B<F)5:,FB*2&7%0.5+2@C*0D70=3*A:69.30*9!4>@1D;B(G,%@.2:.*B-.)&!H=:F3>%9<&D&D&H.67E%,((2>+E&.1$.*?3>7*D>4#33C+F2+9F7F7%=+@BF52?:'72BBA2&&C&>-&9/:=!>.$&8)+H?F-5;=!37::"G(,'1H579$:8H>4<=%&G:3*+GHG)%5@?6B/G;(&$<'14E:C-,BF*>+@G!'(96H&+/7
@r978
TNNTNTCANTNTGGNCATCTGANATNAATNANCNATNNNAGNNNNNCCANTCNCGNNTGGNANNACNTATNNAANGNNNNCCTNNTACCNNGGAANANNTAGNANNNTGANNAANANTAANNNNNGNNNAANNANCCANNANNNTNCANAANNNANANNNNGTGTGTTGAGCNTNGCTNTNAANTNTTGNTGNNNNT
+
"!"!$"$!!#""$$!$"#"##$##$"$!!!$##$$"!#$#!!"!!#$!"$$!""$"!$"#""!!#"!$$""!$!"!"#!!#$$#"#$#$#"!!$#$#!#!#"$#$!"#$"!!##!!"$$!$$"#$"!"$$$#!##$$$$#$"###!$#!#$!###"$!!$$#!#$#$$##!##"#$$!##$##"""$!!!!#$$$#$
@r979
NCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCG
+
&.:FE7/?EH3=:C'5,7>.,9#;!238<590B3D1E@E7,#53DB=D7G*=E4;C6.;1%<7=
@r980
TTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCT
+
4-G87A=!)*2D@@#)(@7B/,8(44F>4D5&&6D/?05A=F1B(0E"5<2&A4<
@r981
GGCTCAGCGGTCAGTTCGCCGCGCGTCAGGTCTTTAACTTT
+
''&*+!!"*')#)(#")''*$&+%'+%"$!&+*''!&#)(*
@r982
GGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCNTGCTA
+
@06E?)!2)204>G,6#?!=4#6DB946D/>4042'0,@B#
@r983
AGACAGGCGAATCGCAATCACTGAAGCTATANAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCAT
+
6>=!1!FA3>GE1632(";@&C-.E1F1H0#H.G,2-:H160/('FG6,$B-814;)F'G1#F<FH5@?AG8D1F;$765*F,F*C@A*$-?G4+2EH.4<H>HB-CB$C%,%5:E2B5
@r984
GCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCC
+
*%+()!(!&"$%!"(()*($#%(+"$""+'"!#)#()+(#&"*#)#%%"*
@r985
AAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTC
+
5?>9?.%#:H*$*G'*&#C9,%96>;<"./7:C&/%?D6'!.773%6&E#3'>4!1>+"7!D>*)<G*B<.+-EE$<*/<85&H*C&A7<B?6*&6.;7A6/H%):H"G&C!#2#*=G%4(-)03!#*C9A'=B&<1'5?0,D9&(+39C??$7?A2
@r986
ANGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCA
+
(!>?;4E5AD&/'=')=5'FH@2;%5.2A*9B3<H!8&&6HD<"H0#=7#'?0(21@34E"&6.#*FFH,24<<8E;-D*<.+(*.99;C*"A+?D3B+0?8>?,!!B(?F,'=%6@&81,?;A
@r987
CTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCACACACCCAGCATGCANACCTNTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGAATAACA
+
B2:$+AA..>G0;3(3F5H'=D@+;@?HE1AC>7(C24G)!(,$,:?,/)@!%:D2>(1,A)F'8+=?(%A=9B)7;9+?0+,DF+=:2&B90+&)5"7DB02!0)8!GHG,;+FBDH73@:0,:A9CA;D'E.4!)G/DF;83?6$C"&,"(;<GAF7#)1?1-7)F1*7,('D;?20<75CA=-5;(+B"77:@.'2&H:4CC7:0>1?$9E2%><4;0)%':H*,&8!F.$F>45D*7#H-G1=;7#32)#5&8%:'AD$?25&?%E9D5(A$6B?(5DC8$*%D,CH</)B-8.$EBA1>'<FFB,2;#(/=@C5G6!+G$7*H*>/$2>D-+7';.-E;(;A$F*4/#2=88<#5DC3@+
@r988
NAGNANANNTCGGNNNNGTNTNTCANNANACCTNNNNTNTNANNNNNTNTAAANNNCATNTNANTGTCGNNTNNNNGACTGNCNTNNA
+
!!!!#!$$##""#"#"!$$##$##$""$$#""""$"!!""!!!!"$"$"$""$!!"!"!"$#$!$"$!#"#$"!!"$"$"""#$!#$$
@r989
CGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTGTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGC
+
+,G//,G-7A5!(&-*<.!FGC!3"F"57))9%&@"!";&141(D:/78<@/$HD"*=32>FEB@2F:!%(E#C2%4%0%D?$;3F(93
@r990
CCGCNNTNTCCNTTGTGGTGNTGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAANCCATGNATGTAACGT
+
$&&&""%!#%!"+%'!*'&#')&*!(!&(*#"%$!$$#)$'%$++!*('$"%$*+!)+""'&#!++$(+(*("'&$*!##!*$(&#$$%+!+($("))+++$"+&!+%')))+)()#*)')$*#''%'+!#)($+"%"(%'&#""*#!#$*$'
@r991
ATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGNAATGCCACAG
+
2-;$0<(!0"&+%&9768H02>><")6>,%"G(FC0<?*;5997G3<?H+5%<*#$?A)G+5>(3F*8HCF'&GC3)D8-H!46/:<&?
@r992
TNATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCANGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGAAGCGGCCTGAATGGCTGTAC
+
!%+!*+(&')$*+"%(!#&)")+*'+'%(*"+!'+")#*!!)""&"+%(!'%#*"%*+$'&(#(%($)&('!!**!&!!$(($'%&!"#+$!#$%)!+$')'!'%!""!*#*(&'()''+("&!%!#!&"*(++)'*(
@r993
GCTTGGGCTAAAAATTCTCGCAATANGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCA
+
99)@9+<DE5:.30=G2;>%/")5+:8<+'%"*E'1@626A***:$8FF-..;BH":,@'F"!3A'
@r994
CACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGT
+
3!?BC<E+$/7:080)-4/C!C&9"D:<'+*#=G=GD4='572)'"4"<
@r995
TCTATTANTGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCC
+
>A"+56:,2F"G6G:->6?-6?8F*D--,!<632,5AA37.D3<6%H:1963E46D*F&A:'AG'@59;82'",9A"7<H%<%*FB3G+7D7"+/FA%7$,-1"FF>(/-1.(AE3H4A),:+>;<*3)$-+B2<"<+78C!20D':BG+:E@5)A.4F>&97,(A,8!"3>A0?&4#E,93-768?1
@r996
ACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGAANAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCNGCCTTTTACAC
+
43C.?.">=&E=)8B"5-G$.%*48>*@:C;::/C#"(@!>.@=2/:$H<E@G!E7A7*>H"!%G!;8#3>D.;-%*!%92&7A300/*((>''4+85D83HE&0,+!;+8>E.804G1&@C&$4>B=?!)H
@r997
NATTGTNCGNAATGCTCTTAGTAATGNATTATCAAAGGTATAGTNATATCTTTTATGTTCATGGATATTTGTAANCCANCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGANTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTATCACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAANGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAANCTTT
+
$"!)%*!)$!(+)'#"+%&((#!%%%&&+$&&!%$"*$"++$"&&%*#"(")("!!$#'"&#$#"&$%(!&')*#'&$(*&)*$!")((#")$!&)"$*)!'++&$#""'!"%(#&%&(+$#)&+&*(&**%)(+)('%'#$%'"%&##*!()%"+!&&""!)'*&##+*!$&&()&#*"%&#&"$'%#')$+$&("&++&!&+'#(#)*$&#+#)($*)#+**&)'&##*%&&(&)(%)+"$$$(('#+)'')'&&&!#%&$!&("'*#($#)"!&#*)"$"$+(*("'&)(#$"('&#$")##"'&*+%*""'$))!!$(%+%!'#%+'+&&#++*#
@r998
TCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGT
+
FFF23@?),GCD*/%184)'<&/;#>#;AC++3%'.GH;:
@r999
TCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATNAGCAGGGCCANTGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCNGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTA
+
50F,3+4(#30(!!D2)($:3@AB90#@EE->:92:?@=.,8"!FF#>4B%,03@*4,0F(#4F=5'!:&->&G8C%345;'3?@7A/@BHF2;C3.,.?G8%6#8&,"640@FF79(!D!!%0H;0;>90'G-)D)*2:E)6.E/?F<060+7F;&GB7,3D8@0:>+
@r1000
AACAACTGAACCGAGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCG
+
-">3:BH-6;$"%,=>&5"*(B8)='?>'&>(6<496';97>*=-2D+1H
@r1001
GGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTNTTT
+
@GAG%40;>59E9&(/$""C+9CF-C>A!)3GC79(<"-G'-&?:#:.2FE/7?E"*&=5146&;&%/A#A5
@r1002
CAGGCGGCAGGGNTGACGTTTAACCANACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTANGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCNTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTCTGNTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAGGAGAACATGGGCACGCTGGAGACCTGGGCAG
+
(7!@<)75H(%/1=%1-4+?2F-/92.A8CF(#?:'8:,447G4!B+.!H*:E5B05(7$@B?'!"$F-5@,,DC042)%E:,$=26F(-AG:8+E?+7C&::BF@"9.C=/+<F%C*=#'+F$;("321(-=)';+68HB$A<*.2CG.A-&<=E7EE9E$F8"<($(@$FAD'-;DC4CH/H?-F4BF3D(A:(2H7D#$B>41839!/EF)>)$&10$)//)%#46H!F#6-/,(:FDG$4!D8.5:*:06;G0*2/(7:+"$B3B9.!5?3;(:&C*'C<+:A0A?D%)8<(3?<<&?#:E9D1#,HA+24/8D@5!D&.16#ACC/(1F4(+E>?!=H5C(("2;<=054/&*%9(E*9<&9.1<$GE
@r1003
TTAAATAGAGCAAATCCCNTTATTGGGGGTAAGACATGAATATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGNGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCNATGGCGTCCCTTCGCGGCAGATATAA
+
:%%@%+<5/;*=/;5"&-@=;(!=;F2.+G="A>G<74C,/(@-0)$"*,4((5G!#@#(0.'''A'1E-&BDGG")G%,+F2F=3-BA:6B./1)8!-80<:);$+ECC1<B<A7-;(4;HDE5=4;,$+20>?(FBB008+%'
@r1004
GCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCC
+
->E>&(2%'@*AF#$D5;B!:FG@E?(*"@E#CD+7'#483#2$D)1,A-61352G35D/%:
@r1005
AATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACT
+
A(3$!8C;$1<*":%5B3BFGH+A#.3>AC9G@@4CB.=8@;@:7+=;D64
@r1006
CCAATGACATATCGGTTGGTCAGGGAAGTTGTGAAGTTCTGGGATATACC
+
?":+8E0"!)B5/1'$/","99,A4@<*'A"$>B&4D.17@<=A?#/2;2
@r1007
TNNNNTGCGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTT
+
(#!!)$%+"!'+*&%&(%("$*)+&"#)$&"'+*"%%!%$))+$'++'+"%&"&+##+%%%!!#%&!'*)$*+*#$$((#*%*$%&*!#&%!))"(%#"(!((((*'&(
@r1008
TAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTC
+
3,'!*)>C&-+-='5=F%?5+?%-2%!(+76!86;2,EHAF40-&+9(6=%GH>5?79G/>;*G!)8-99G)(16='@,8F&%&H2?"E+=
@r1009
ATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCC
+
G'-0<1B>8/(!%'EH(/G3/E%'9A3>$'82%6,=-%;.D1G962A2&3-DE&8
@r1010
TGNGTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACA
+
%&!$+"")!'+*&*&&!&#&#(**%''$'*&*"!%$"%$#(("+&)'"'$%
@r1011
AGGTGCCGCAGCAGTTGTCCGGTAANGTCCGGCATCCCACNGAGCAG
+
&865$4G2$CF">&A7<':5;G2;-F">?7?3(CDF>*)@4'B+0#G
@r1012
GGGANATTTNTATGTGATGTACAGAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGT
+
)&#)#)&(*!+"'(++&'*(&'"$$$%+*#&#***&+(*!(&#)*+%&$*'&")'$('&$(%%*)$%+"%*"$&$"!###''
@r1013
TGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCG
+
8,B/&!=!%B65C=&52A.<3!5&4.)@&2%):(?#B4?BA.)+$B,-%,@G6FA,,,6A2("0?DB=
@r1014
GGCNGNCAANAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCNGCGTGAATGTGTCTG
+
%(*!($%&*#+&+)'%*'!)+)&(%''&#)*%()*+*))*+#('$%*%"*)*'%++#*!&)*!('
@r1015
CACTTATTCATTAATAGATAAAAANTTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATCTTAATCTCAGCAAATTAAGCGATGGTTTTAAANATAACCTTCTTAAAGCTATTCAGGACTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATNACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTCCTCCCGGATTCAGTGA
+
3FH.G.:CB1A:A-1":6,G37.@'80E/0E0>@#!=<0!/F2.,2+EB'7H,5"$<9//7!1)A/G&/0C?A2"(,#)<2+4D1!85'631<A5&#+1*:7(?'#99->C>>H>C!<,2'2@=2F)+E6F4>36D?669:*,*G!9/4F853'#3>B&389=%:*9DFD-8(.=?3G'+9E?86:<?G)D$;/E+@*D4;861><3&%<.=9C05*(*$2H,:<;!$"4)"+F5*54!*F:+31%@2$$DG&8@'9D93#/,62G#2)$,E!$)$A5"E<F$#5-187>0?>A5$'6B<93%F83H:C4&781*10@+;)
@r1016
CGTCANAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGNTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATTAACCAAATCGCNCACCGAG
+
+D)97-?$,=G'&''0'$>C9BF!(CB":$"@<2F)BA6FC7*6&B89$7#?C>$+*6H>.9=48@262'F/<53;EB0@&<9;9&4F#)>"D@'6:#?1+-5*"09/"(DH(8'-498%,+=B07%.H'=(>;.<%03?785/+..0%BEB@73<2<''$H&3=B@A2#/;58E=8'FC,'GA"-%:G=A$>D?74!%*3:&8G66F('C=.%&G)B)E(%)(9;F3%>.E)F>0,B$E-?,#)+$='H43?@E1-@F.!)?%DD@DB'(8+A61C.&8(7G??!+?<.H4<FC
@r1017
GTTGCCAGTGGGTNCTGGCTTTTCGGGAAAACGGGATCACCACGA
+
2=,'>D"3@#3*#11H?4(F):77(@4G54E%0A2H#*%5;E,1=
@r1018
CGAAGGATGGCAGCGTGATTTCACAGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCG
+
*A3*G*&EC!)5,.)73;:92-,$1B$1&-BH4*(=%4,4.HFG/0/6(4"9"(-!7"61C?,G2//B(&'?/56B),$D#877#(9*0
@r1019
CGTGAGTTACCCGGCGGGCGCGCNTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCNTGATGGAGCAGATGAAGATGCNCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAGTGNGCTGGATNCGCAGTCAGCGATGGATTTTATTCTGNGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGANGCCG
+
-?>'?<3>+?&D5==*?:;A#4-",/!6!G$H61!#;=-"=B5>(FA*,!@49#3*3.+#&*?>+;.E-8F'3*=-<'C>C#B!G.,:&&"=/!H'24.2/9,B:&B$E9?'74-!0!0)E2?=6G75$$6%:?!7$/&<B,B$?B?7B)=9$A0???/G*=CG#5$985++#6HB?9!3"87<$5:28)*66=&GC&0#9$/6?11A)#A6#),293&")28&2179>7/&&B<%E((;4?;!'GG7!@5394)=C..H2#H3<-#8DB1E>!EC/2:C8:,5B!@%H))E0G59B8:6-0,G($+5"?AAG@E&1-;-E(&@>)<B>"C<+0<$C
@r1020
AGGCACCAGAAATAAACCCAAGCCAATCCCAAAAGAATCTGNCGTAAAAACCTTCTACTACACGGCTCACCTGTGGGATATCCGGTGGC
+
%"+##!+(##!!'*)!%&")$$%&%$!!(#(*'&%#''!'#+'))"&+""*%+'($++!+$!(')+&$)'')'*+%)'##)"+$!*$!"
@r1021
CCGGTATCNAATCTTTTAGCTCGTTCCATGTCCTGATGCAGGGCNTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCT
+
*+&2%34B0G52=7%/7:)2&!9!F"""$D/6A6+@(8=)4>,">EF*,-57.C36<*50?:C--+-HH#D4"")D/6H926B3==07<:1$#@98;%9
@r1022
TGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACNTCAAACGCCGCGACCAGGAGA
+
.0H@1B=$/5#?G+#8*<?G37'#2#1A6)G=!>'/D55#/3)A79*E;+D4;??!FA4</:=
@r1023
CGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCC
+
/&/>DC=8C8'>&(C58&""1678<B1(%,B>AC&DA)E;BA'108!2>*9$..?/=-$"7F#"7=".=&
@r1024
TTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATG
+
D3*$'55#55@?C,E58/&&!>50D%&)0/<0F&::A8=F=FH<.2E-561*"!/5;*/C@>BF$+7!$#
@r1025
CCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCT
+
$=9;!$D)@?C.>>"!H;5+B.8"%<#6.</;H7.%4*H&##-!C&&)9B;35%G"#F(</&&23(H!74@C41@9BD*484>&C*'*.(9.+5#2%E.HC4%06",.<2BH&%D/?-A9E6)A<><,+9%=G;*G-D#G>&-E/&(2D;G9>E$9B,GA?%:=(C((<:*F4G#1?F<03F*-4#;/=F>"F<16*/*CE91H*A."D?;>7AC?"FB1%)>86=E.5*,3'F8+9C@+>0%)<F9%-
@r1026
CAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATT
+
2<,F<,."EE3>,,-E8518;DD&/#364@3%?@;7.$>BF:#"#4)35
@r1027
GGCGTANTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTA
+
$'$$$'!&($))+%+#!+)$#'##&$!'('!()!$"$+#$#$%**&'
@r1028
CACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAG
+
%F'D?C(9G"31"=9>36GFD&@$7?%@D@+0*)&FE#$"G+G679-F**&C?)H(77(8$%*>2=7<=D4C&#07$-+(!*B;&
@r1029
GAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCNCCGAGTGAAAGTGTGGATGCAGCCCTGTTGCNCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGCCATCGGGGAGGAAGAAGCCC
+
3*5*9*5-87(;@-8"=%*-&8+&)<:H6A55"CH*.A>C3*G,8G:'*C.CD8'84'DF$0@E18&!/8:%2H2<9+#:2((&?.@&0GG'5*DGF).<?;<224)A1&E:9:37.#"8,?7A8.E-8?'99=9!)(#@6#:>8>9=(=?&&-;3&(<!(B,&FHG0+:$3!"5HD<B(3D%D+@EG?1):-E(E0*D)&$G>D@D";.=+.C1<0:+&#6.8D(-!''C&C5>=;5DG<%!AG=$84';;F$$5
@r1030
AAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGNTGTCATTAATCTG
+
@.2(;6(9(+.<A#)CD)91AHD3F1>8F&<1F1)'**%%F!F9&4C()7F5"B160(?$2:C);FGB>35'#;*G''@@.%F1,4GA)?(4"8914/A&256>09@7<'!$*(C/;6C9F1:##<6C:&
@r1031
TGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAG
+
#8-GCGA(/<@/0*4"HH,;!,7?0C@B'.'E7!+<2->3B&.
@r1032
GCGAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCATTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCC
+
:20A/2D@%813;B!07;A>5>C/4G15,3;GA1:/@+$G.@>,-7&84@=C#=,0#2HDC('?"5#</;CE01?-'H9<DA<6%3H*F@$9H+!/@D$,)#%%,!/!0DHE5'=)#6A5:?+?6!0,A>E6!/C>8=$,9C"0!)A$4;7-6-$5FCC*-$&?B0#H0%,"2(+B4-F?<:HE"H0+B%.?*9?%.F@<99>-0",>?EEA:'58+C"#6$E7,;35@$A",@9$@//40)
@r1033
AGACGTGGGAGGCGAAAATTGGCGAACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAG
+
2F!7-@"65E+,,>-'91A!3<H',=;'%6(E0!?-!F>$%>.G6%HC(5).4*"8<1/!'E#?C0?
@r1034
TATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCANGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAGCGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGNTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGC
+
%,5(7761)2D2-"C>*4)7-)>DG3;>1B134),@4@7*;C*<:$G2"C)<1DD+!(FG">$3>9"$9C!*!2/!8!1A;$8>-@0(/)H"1;).H'2/7@8)C=;G7C!@;;+"1F8?0"9CC"0+$(?4:!7::>8!-)G;;72593)75>*!?=&BF3A@2=A)2<4-4<=&94A'1**+/<!A"*;C@82D4:80;GA#*:G4)+*D*9<#$<2=D6B/!@:'2&=%*(1#/4B$F76&2/0%:.&@6>',27F)
@r1035
CCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATTTCCGCCACATCCGGGGAAGCG
+
+*+(%""!%!!($)%!%+!*+%')'!+$!'"+!(!#'"++*+)$+!''**$+%#"$!++$$'*%%"*%))$!#((
@r1036
CTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGNATTTTATGCGCGCNCGAAAAGCATCAGGTCTTTCCTTCGAAGGG
+
%//D,,2=-*$'4%G=;&8408()+;!0$(9?@CC79>)F+-43*6>:"!7HH$;6,E,-54$7>34":1&&!,C<6(0D62-
@r1037
GGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATCCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAG
+
F?!B(B=&7*,9?C'7."1+2+.EA*4%$/3*>;87D3G'(B*E52+1D48=G4F!(&"C$@-/@5.9<-#%5=#-"3:62:G2&#FD0"8DB=6?$'F.7@+>62.&';01/FE=,-<6'&>:%:9B,'&D=51A&H'#2&=G*CH(6
@r1038
GAGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTNGCGATGTCCCTGTGGCATAACCATCCGCA
+
5HGH,<@=<8C&)$7E"+AB+">74HFC2=G/7.66FH2?'&/>C%(;),02&@D1'C/E&2**G
@r1039
AACNANGTANGNNNATCANGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACC
+
**$*$"(!!$'%$"'&$+*#####""(*)**)*))%+$%!(&##%"!*"+*&%$(+'
@r1040
TTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAANGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATNGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATNTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAA
+
7,%-,4).+1)02F:GC@&!C7&?(=?DE;8F=2B82(#<B<FED;E98:=5#,A!C*7;B'?$1C3G2;CG*13'F9$&$)&#'8+:#!D'G!A(D7009&&/10%<)G0591,/")-88,1@DD>;0?E($$D=5>A8A-:)6H.6;8/3G-85#CD.?+,:."/HF,,%&*;?@%HD82FB5='G@#1##%-%'B.9:B38/0@,H>.FA269&(A46;16&":E%("B2<&48
@r1041
TACGNNGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACNTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGC
+
#$'*%&+*$++%&##$!$+#"#!''*#$&))"')&'+$(*&!)'&)&&)#&++$'))!"!("&"((*#!+!#'*('#'"#%#&&#%!*")#+!!**$"*+$"&""()")(%!**(($'%)!+&("'&)$'%%"&!*%+"$+(%())!$$#%)'*'#!!$*%&
@r1042
GCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTAC
+
@4/(".>H.%+?B/:E"AB3;.>:3E/6C@?HG(.<7"E)+"@:":C$2$#=594$CH>#2*!+/%-F;>DH-,?-D3A:%$4#D/:<;=FB!4
@r1043
NNANNGCCNCNCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCAC
+
%!##!$&$")#+##&%!##)$'++#((+)#"'*%%!!*&!&&+%($)&)$%"')+*%*(($$)$!%#($(!*%#%&")%#!#%&$*"*("
@r1044
GGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGANAATTA
+
#)+!&$'%"($((%#!#!$&'#((!%''""&''("&%)%)$((!#&&)($))+)+)++%$"%')!#+"++%&"#%*#)&'+!(%!")+&!##(()'#+'*"*#)*
@r1045
CCGGGCAGCATGGCAGACAGCCGGTCGCNGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGT
+
&G;)7##.H9E95,'@:('.7-*$>)7G22;'>.@+7"F2F#%:3A3*:8332HBDA!+D+4,4<?/G&?E8+B#=;=$4-",2<(73F0/@))/*$#+;572E(5%F?.?(!1+F#,3
@r1046
ATGTTTGGACCAAATAAAAACANCTCAGAATGGTGCANCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTNAAATTGGGGGATTGCTATCCCTCAAAA
+
?.!6:94.>5%/B4F>EB&=CG'DB%HE+#@/37%50C(FA#21H"5!'?:B-1C9AF(D"DHC2=HE##%10>%C30F$)6$D$$6;$=$(&4GB7%8!,;!0/,6$4(BB#A
@r1047
ATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCA
+
?2??2%A;G0)#F/"%D?<)1>$$6<GC%)D@A>*'1D5:('97,G8G:>@)GED+?>313,?993E#FABF>'6"06=(B,1@6:-0@21<;>'96;
@r1048
CAGCAAACTCACCATTACCGGNTACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGT
+
<@H3AB#?8D<#D7/F#B>B0B@(5(BE(B*4$-.D<;$F.B9D='$)>@@10!9-&*F"
@r1049
NTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCT
+
+EHE%&9-+1<"!*)H/5$;)#A=/7<""A"->:G0"3:A*;")GF8>(('*"0*"7!:,36F;;7D87A@#6@9%?F,(H4*/0-,@<?:::@+3CE'684A"??.4F*3-<%8-'(EG>(82*%3(7/74E(00:H4)E+(D.H*
@r1050
GCNCCNTTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGA
+
"('&&!$+%))'!*$!!#&*)#')$'"#*&&"'#()(#'%(&"*%)+#+"""($##"&!(%*+)"&+%(*%!%'()&'+&*$)+$""
@r1051
AAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAAATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCGGCCTGATGGCGGTTTTTTCTTGCGTGTAAT
+
G'>A4.F'@:2-&,(&6*<#.!'1A77EC6+!G:.#D>?9,6>=G77%8/-%2-*-G'&,?-1"F3#;3BF?".5((:./!8*?"F%(9<(=B8:44#=D0D8=-=+<=*3'G9,D-22G<':=5B45;,C/G=98B.':66<:59;/1%8@)/-:A&E1<!F))B99@<'&G&/%7"@.5B?FA+44,9!HHA
@r1052
GTACGGTACAGCCGTGAGTGCCGATGCACATGCGCATACANTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCC
+
A%,=;%H#<,2BBHE))E1+)'>CG(2'9#0<2#,%C)=E*0/<?30.FA5H9;@>'?0!+?>./!$9$F#<-=46%6A;+H'&$6?F
@r1053
CATCATGGTAANCGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCT
+
+$&"*)#%***&(&!+%(")!(+%!(''+%))+&')+*""'%&(#)%$(#'$%
@r1054
GNGNATGCGAATAATAAAAAAGNAGCCTGTAGCTCCCTGATGATTTTGCTTTT
+
')%"$+++)*&&%+(*'+&)*)()++('#*$%"*&'+%+("""!+%#)!+("+
@r1055
NATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCTATCANTCC
+
)''+%+(+!(*'(&(()&*#"#+"+(#*#%%*'!+&&%""%!!#'#+%+*"*(#')&$!#('("&&+"%*(!+$"++*&#+*&%&"%"
@r1056
CCANTGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGC
+
($'$#%'+")!((*%"&%+%"&%'))*&+&""+"'%!!$(&#$&!'
@r1057
ACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAG
+
1/D"(F>B,9'(&><<@A:6#@(@7/!@G.DB1)9(A5E0"G#B',E
@r1058
ATCAATAAATATTATCCNTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTAT
+
CE++B9=B70+F%F+0->(=9>A4236<=)=!B$E,)DG3($4;:+-0?*5A=D/="2!'%.'%:F+4G():)9D*H$4(:CF-+/%-48=G(/AF#?BC/:.:3A?/D*
@r1059
GGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGT
+
?G)-#<C!6&$G8D%6&-./(*70%65E(B2'0&8A)?A<8.0D$&D.+C.=
@r1060
CACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGNCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTAATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGNTTTTT
+
7'0'));":<D7),A(008AFF'F)9C)6=,;C7'G>D=:9':=$/!!0./@0*B39.4$CHD9413#AFCD272&B0(@DBH!:*=H@*A6H<5B*.9E/@F$#BE%B&C%&1*+3:?;8:3E$E-,E991F(G-:C93G29=A0<:.%7(;*$(8848'8)3+9&)?5*<H%E)B+=:;3G'5;DC#3(8"/4B?"%"@9'73'EA*?4,&!=DD5A;GEG>?,H5422/**?,HH#,.E73F0,'57<#;7E.B6$+#9+!%!$,@G6<<2!/G9*6G7G71!08?>CF!G-?,5*,3&:@@//&!1)5E,3>7605
@r1061
ACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTA
+
0CB@1("<>C=9+$3(>,FA<:/7A4?"E2;&>:G<3!<C?A?D7:"C<'
@r1062
GACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGT
+
2"!GG.3*2@0-F.837,')B,*:,.C'+>/G!A0#03D986G1B/<183?>#3E3G<-7C':'ECG
@r1063
NTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCC
+
73':G&"7F!;EBE!/B=C<DBCE"%8:(A>5<*A..A&(C553A;$3*B+*'3;10A>@$:"*3G53&&:-45=?%#'>.:&!A@(2'F3#%*E4
@r1064
AAGACAAACTCACCACGGTGAACAATCCCCGCTGGATCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGC
+
7;7%H8*;:/:>%=');?98,#22<E9<@=3CC(:9F5)>C,/5#442F$'F"(4!0BE75.'.9&BF@D3G>$+!$86EC3C34!@F*,(7#.A&E0E,-08<(-,E;@$GG'B
@r1065
CATCTCTTCAGCTATCTCAGCATTGGTNACCTTGTTCAGAGGGGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCG
+
='$678435'9F1B?D!A;-8B%$G+#)*D9!6@,?%8)#?9HH(H/($D.1G4*8%F6/)(&1<@GD/,/.0/.-H7,,A;3)6!.548:?<8
@r1066
GGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGGGTGACAAGTCCACGT
+
<6/5>1?-+>@!=2+*@C91E/='@:B':A<F37?)%18.0>;*1*H$7/D=5%</"318@&96;881%A<"#H46!85?0(?!3G
@r1067
ATCCGCACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCA
+
9D-2:5$20%97A3&9A)1=!B5<&:G3$0-!02>#,"?751FC7=%.8-+H7+038A16/A
@r1068
NACAACTTCAGACAATACAAATCATCGACACTGAATACGGGGCAACCTCATGTNA
+
%4"6G0D*$:5&$;8&C)<)DDA=7F.6.14GH+&A"G-2.4:B?=51*.CB%6B
@r1069
TAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGAT
+
*/H,"#9)<"B*;:-,-,$+4-$HC+=@;!?=6DB@0)).6#=05!@$>E?C4@7!0*FB93$)%%07+
@r1070
TNNANACANTCTGTATNANCAGNCGGNNNCNGCCACCGNNNGNNNGGCTNAGNGTGANTNNNACTGNACANTTAGAAANNNTNNCCGNNNNNNTN
+
"$###!""$!#"!"!!$$$!###!"#!#!$#!!#####$"###!"#$"#!!"#!##!#""$!#$#!#"""#!!!"$$$!#"""!#$#!!#!!!$!
@r1071
AAAAACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTNCCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCANGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGC
+
9*>HH-A4F!6<8:$9/282:B=;'7F'1'F2)/!#CHG$+9)95.6G?CB2*>%DE?3*AF>*E<,1-$69.0"#''C5'!D.<'?22.)$-73<6"A98B":E/5*:AHE.9C0%'/57D$A9*'(B*5D=(=2'@F2D"54(@!@8A.9$6D1@H/,:@2*HF'?*<3D%<1?!B*A2H?%H7#6GD%#.$:*F*5$0!+:@4-.20?CGH?.5")/B$0.239!+2)<#>G*C'9F1?(E:5E@01:952&G+-+;'+,+4,
@r1072
GTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAG
+
8BFH?6<30F*#-*0&@E869EDE@/,+)%*4%C8255-:,(A@.2
@r1073
NANTAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTAN
+
'#+*'*%+&#(%!%'"*))$+"*)*")%&!"*&)($'#&"$*"'&"(#($+&"+%*$#$&%%%
@r1074
GTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAGGTCGATT
+
12">9%9G8<FD3?,7!7,D8@B!.&.HE1.E&=$.GF&!1*5!''C<>E3)<6>
@r1075
GCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCNGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTCAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCNGAGCAGGA
+
?%50:+-6%?,$97B><.&D.;:$&E%?7931+4.H)1F'B8E930@-E+GE.F2C4F302(,$;8%&E"F5?,6),07G(&&=$5785,(54B!";:@/;=;0.-99>#(E>.;B&"#.!$>,@E1;;$<"GD:%$5::=>G'9<88*&1=A6#&/!0./:B.&6C"?:<11!?-&.'CE?D+?*A&;(==&584?*+/0:'/7&2%&)CG<A/>=+C
@r1076
GACGGGCTGGAGCCTTCAACGCGCACGCCCTGNCCGGCATAGCTG
+
G@"D/$301,D&&!;H=/<H&2C+!1:.HH%6=E*1!+"@A6H&H
@r1077
CAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGAT
+
CH.:D%";0:2!<!CF7/09%G'EB@,)F()*3!8'0;:)*5B3<!$1F</E1'&/@'3?H,#B?8048>)F2-@$>%,<E9:.2<4!*<*>@-==6.*+,E.).%2,)@GD+F17)//B(D-/A0FE!*0?6C$$&)'4)F;
@r1078
CACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAG
+
&G(2B;!#88F1C%C1:;$D,G&4;7)C.>1&6H-7'?$!@6*08*7;%4;?*EE(:
@r1079
TGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATNGTGGCGGGGGCATTTGACTGC
+
')</H/*#8,>H4#$04!9%B)<&'6;4=%?4.D+0@6*"5//6?<?.B*37F26H36"FA%
@r1080
GATGGCCATACGACCGGAGCCTATACAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAA
+
(A//9@5DCE;%)2!59,!!!C8)?8?'&!&0E7A(3:27@B98843'&#H,9<';6-@3<A
@r1081
TAAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGAC
+
))H!!.F,(:"+,7')=>=F@E8:+&=+@?&H6!%DH12E??E<!-E;)C398G5$<=GG<C>!=.0=-?..!83G
@r1082
CCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTT
+
5;!8C-%6=:5)C>H?$B=F<F:">8)4;&D*)'.FF;=%.F20#
@r1083
GAACNAATTTGGATGCACAAAGACGCCGCCGCGAACNTCGCGCAGAGAAACAGGCTCAATGGAANGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGNAAAACCAGTTAACCGCCCTATTCTCT
+
(&$!"!%""+"$(+"#$'*#((!"$"%+)"&!+(")"$'!**(%&'$&$(&+))$)!'&%%*%&#)''$"*!#%+""&*'$+('!#($#"($'+%&&%+(#(#("(%(!&%*&")#+&%$")$
@r1084
GCTGGATCTCAGTGCGCTGCTNGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAG
+
B+/6%E+6B!:DB=H&)(1<>3.AF08><&;,B9A1(:.2;91G0G5@1/",8E=+"C:.(=:C/(0H=-%1<2;-7(5:(A:/++,3(1$@C(F2F"0;1H;02.!%G=B)9$9@1!:=)(D::"A7*;.2(-%;35AE9E!"59$D'70=C"->B=FB;!7
@r1085
TCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCGTGG
+
E6:#-D5<,$.-4C-@9;%2:#*C#2;*04;7E/?<0D48CEG+=HBH.G#"-$!(F<1)=!)<"<*=D+1):*$56+*ACDH&)=:*0+2B098*H/-8-*0/96:GECH+.:'7)0G=<;G1*H/3)F=)9;&$36D!D6-/<2;8D5-D*747"!G4>
@r1086
TCCGGAAGTTAGCGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTT
+
@4%>B*-!/44A!>>E2<$!'$B2*;"-?83A)D+)C#(?H?HE6*,*B.<.?F,"A1;3@*-04"
@r1087
TNNAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTCAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGT
+
('+()%+)("%'+*$$*+)#("$'#(%*)*)*+'+"&#!')+*$(&&!%*)$"('!"$"+!*+%&'$$%%!)'+"&+!'$%%'%'+++"&
@r1088
GCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATTAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCNTCCGCAGAAGACG
+
-"(26@F-($;!*'A((+1D8?2;(<+*FD9%*)AC,<.%@50D&?)A$)3&1+)*D#!"4!*4C44?CEH,?>0(7#:F(4&0,9(?':6=/34HB/CG5&60+C;'D72
@r1089
CGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGATTTCTCCGCCAAGAA
+
E<=8((*C2G?E/:28)/&96A6/GE9:EC;9A425,B385!2F46;/?8$07:
@r1090
TGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTA
+
;5$/3@@38.)'$1*!3/H-94GG"5@BED68&G2<<.FE
@r1091
AGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGAT
+
C.1""E&(46G::&"/9#(.@*0B>3&)1E+4;$ED:!3$&=E:*.5#B'G
@r1092
TTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTTGCTGTCTCGCCACACGTCCTCCTCTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGNTTNNANTAAGGTTGATTTGGTCGGAAGCGGTT
+
?H*B=;5+B,:<91?:=3-:=!'H0D(<3'C.1,A>!(;CGA1*<6.>)1&$!!=@#G76/B<!2/C8G=45&?'66:96F)E-)H;;&A"45"H0;"F%.=4D"H9:%#+(/AGFH%9=*+&5)/F.6<BF&.=>.+!%.F%@D@?0><:G/:#F;>,)?@
@r1093
GCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCC
+
<1";=>+60A'5'%84)-764/$;@EAA:9*B.53>.'5+%'?;*<=6F<8BB87:E,5'F0:E=&D&98)*:(6HD"7F?('.CE'&=,EE!75C'52&A7FA!H0-"-
@r1094
ACTGANTACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAAC
+
B9;1H+E92!B7%B6:/=(">1.!:80&0.<$F76<AA!47/F48=!$:'GE
@r1095
ATGCCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGNTTCGACGAATTTTCGCNGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGG
+
#%(($+#'*#!+*)#!*+)(**#"$$#"$)+%$(+'$)#%($#$*'!%("&$&*(+$$!'*'&$#(#!(+$*&&)%))$)$)$%+"("%+!'#+"*$")+')&%"'*#!'&!
@r1096
CCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATNGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCG
+
B+,0BFH03@/+$<'6E1E41%"!32-G5CC+8.@#3H)';6:3DGE*GA%E3:@->/A!.*&2F*A%A%9?5/;C.8"B)8H!@0?,/:C=5A:3$!)3=6:C;C"2.)>7<"?'C$7GH,#.?.*F42D8*/*G:-<25#FD8&"04F#=DB3/&E?*;>:11F9995
@r1097
CAATCACGACATAATGCAGGCCTTCACGCTTCATACGCNGGTCATAGTTGGCAAAGTACCAGGCATTTTTTC
+
4#1#CH:44#$<#?.C-5&@+H/'#!B=&91$1-4A*32!?+9831;>!1$)>'D8;=/==?*'%G<2$%1G
@r1098
NNTCNCNNCCNACNCNACNTGTCNNNGNANNGAANNANNTTTNNAGTNNNNNNGGNGNANNTGGNCNGNAATCTGCATNNGNCANTTGNNNANCNTANATGNNATGTNNNCTNN
+
!##$!!#!##"#!"""#"$"!$$#!##!#!!"!#$#!$#$$!##!"$!!#!$""$!!!$"#!#$##$$!$!!""$"#$!$!!!!$#$#"!"#$""$""$#""$"#!!"##"$"$
@r1099
CCTTCAGCGGTGTCTGCCGTCTGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTCACTGACAGACTGCTTTGATGTGCAACAGACGACGANCAGCGGCAACATCATCACGCAGAGCATCATTTTCAACTTTAGCATCAGCTAACTCCTTCGTG
+
)"+''"%(&"+*$*!!*$&+'$!&"$%#)*"!)!#(*""#')'*+))'!&$++#('+&#!&(#('!"+)!'"+$''+%$)'!*#(%''("(##*$*&!$*()%$''%%&)&*'$($*))#())""!$%#'*"!*"&+(&!*")'&+*#''+#"')'(*!$#)!!!%%"%$
@r1100
TTATGGTGATCAGTCAACCNCCAGGGAATAATCCTTNATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTAT
+
"=D+,G=2??,?!;42>'8!)!BD.6+<DB&;;>H<7C2C!D03!H.D,C@6.'F-&<=2<-B141,',8H=3E5D9&H!64'<?3E,G>0.356!>B$061A8;/F)
@r1101
TTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAG
+
#H?(=!7')0<$D$00/>>(B0;$-*1/78&!$:HB$?G-?
@r1102
ATNTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTG
+
&''(*)%)')$$+)$$""+&##&'$%!+($)$"'&(%&#%!%(")"(%"
@r1103
GAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATNAAGCACTGCACTGG
+
)@?6,1=4!H6>+'D-66;3>5+=<)F'?>HA0=&C67",";6.A=E7!B!GF&#(3F2((0$A>E->!24H&7@;%!%9"57:G+&%,@6/56'7?C9*G7!?$'9'
@r1104
NNTCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAACCAGCNTACCCAAAACTTGCTGTCG
+
#)-D&463@#(2G&-#);61D05+&124"/C-7!=@E*'7(7AFA&#&$H<!";0$"@+HC79>+$*4*-+&14+<A-"':'C4,G!>62+?B.85=A;B"+!59H1':,G/#8%8A5$@8)8:D@@'89*79,?DE,*"(A#@B'7%G#-@/
@r1105
ANCNNCNACATCTTCCNCCACCTNNGCNCCNNANTNATCAGNGANCGNCACTTCAGNACGAGATGCNCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGNGACAGAGGCTGCGTGAAGTGCGGTATCAGCATCGC
+
%#)$(("&%!)'*!%'#'%*&$%$&&!!"&!!%$!%$&'&$")$"#"&(*%%&$)$+%!**!**)!"%+#"#&#$!+(%$)'&*%)""(#%)&!$'(#!**'#!**((&")$)#'!#$!$$+)$!!##&#&)*!#+'))'&#!*(!*'&'"&+#&&#%)"'%'&%!*!"&!***!'$##)#&(**"&!"%($")#)'$''$"++*)'")*(%+($)'("+!"&(*(!!#+(#'"(!($()#*)((+&"&#!(+#+!++++!!!+'('%&$*%#')&*)"#*#+%(+(!&"(*#%!$##'(&+'++#$###)&#'$"*%!+#*+
@r1106
TCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACT
+
-3=+>">:=+B<#%C(057:$4F>#("9/EE//8?7='>C>?E+H6
@r1107
AAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTG
+
;-&+"2,/4/FE2C*+F";4)"4G#0!1,?H.D-/D)(;A-5F?!<G;
@r1108
CTTNAANCACAAGCCAGAATGCAGAANCACTGGNTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTNAGCTCAGGTGAGAACATCCCTGCCTGAACATGANAAAAAACAGGNTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTNCATACATCTCGCAGATTTCTCTGGCGATTGAAGGGCTAA
+
&)'"(*")$$+))$#+$'!*)*)))''+)#%!&#'$"*%(#%$+$%"'$(")%'($+*+(%%(+#&+%'#&&%*(*(%#+*(%'#%'+(+$#""()'"'+#!&"&&"(+"*"")($+'!%!+(!*+#(#(!**+**%#+"+*#'&+"'+"''&$'%*"(+'(&'*'%&)$#(*$+'+$)'+%'**(%%"#)$"!'+)*$+****#')(())%!
@r1109
ANTCTGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAA
+
'!$&!+!(%)!&!'%'#$!**+'*""#"%(&(##(')#''(*&()*'%!#$*'"!)'*&#***!')(&#+%'%""
@r1110
ACAAGTCCGGCACNTTCCGTTTTGAGGATGTNCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCCTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTNTACGGGATTTTTTTATGTGATG
+
!<?BA-.#BG2->6%&44G&"2%5*)<D&)%#/8("+6@G.:%?%%98)&A)E3#6:.&E9H59F%%=CH1&C6982$:>#G8("0:.G"E</1H8-'9F$"FE-9;FHE?+&G/>?-C<5-<8(/E+8'-G/>(*A68201G.3C**G,%*$/?9&*-;+#<#
@r1111
CGGNNNNGCNGAGNCCACCTCATTTTCATGTCNGGTCAGCACNTTTTCCCGGCTGAGAGGGGT
+
%*)!""$))")%'+"%#&"(%%!%*($!#('%&**+$*'!&!!#*"'+'*+)")*%)(*+!($
@r1112
ATGCCGGTNATCACGGCGGTGGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGNAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCNTGGCAATGCCCGCGCA
+
1$79,=2!8&:23.A?#!(;:&5;H1(-%='&<*&D'*+3*H%<C4::274$!414A+=C"!/>$,!9;!@6<',@*/DH+EA!6<1@C1&!E*:3EH3,A3F%$80)A9A17H@A+!:
@r1113
TTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTG
+
#;F19F>=D?=?-D=*04@)85H&BD"4&F(+-3!%/.*1E6/2>A
@r1114
CGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCG
+
D(*=F>A@>A6(D=>H%&;F6E5/HF136+=!)*H=56.(5H(82?/>49
@r1115
AATTTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCT
+
BG4BE"3',+@4GD(/42"EA;#:F??/9A/A%9"<0A083(H)7D+D7$+"%?489GF8?)=-6:+GE)=%D
@r1116
CACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCANCGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGNGAAC
+
7A<AC3#AA&C'(C:F&D64%F"892!:=)',@H-(:9+7'56+.=%>!3D6,8%+F%A;0;!/E74</'+1=&$+5$$.<D6>E:!66%*66.,0&-2E<*HH;/1D2%$"'<55;47(-/@3)$0!A:+/40$,3=;508*(+!,74))H980'6/.A*%:35AH.<6,$G
@r1117
AATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGC
+
):,!(!<@2?3@3G;>4142+/'.)*-:$$45#0/?;&;'18CH(7*%.0+=.
@r1118
TCACTGGCTGCTTAATGGNGGTNGCTGGTTCTTTAATCTCGATTAC
+
HC#<A%#'=+3G>-*>E'A.+:37D?(40#5/1>*8<3(8/F2&5G
@r1119
NAGCGTATTGAAGGCTCGGTATGGCNAAAGTCCATCCGTGGCTCCACGCCAAANGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAN
+
$+&*$&AFH$9C=F./9D&#)-5=5F%>E?$8!'6D<16G(8!&H917#*';9!G+H-E9"CG8BBC%,F6;'"68%D-?*+2";)E)?
@r1120
CGCAGCAGCTGACTGCTGAAGAGCAGCTCGAAAAATGGGTGGATGGCAGG
+
2G.E,)F;,F>FA$:>F:,/=/A8+)&8>9"E2-,8-#+FB1()?$2GB,
@r1121
CTCCATCCACGCAACCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTNGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCAT
+
+ABEH@!BHCH>*2=F,./;67GH$BA":.*:(;2F2DA;+0+:;(E9-3=E>65@><CD*,%:3CDC7)H@+$<H33*G9;-"+"51)$B>A$+#>65G2,6B&*/F*.-;,7E:421:0./-6?C;6(!;D?/#/89>G9F;%BAC+%8,/$8E8&3@?1*E.4%?F1@5@
@r1122
TNGTGGTGCNNNGANATNCNACNTNCNTNTNNNNNNCCNNNGNCCTANNGGNAGNCATCCNTCNANNNCANATTNANNANNNNNGTTNAACNNNCANNTANCANATTANNCGNCCNGANANATATNGTNNTNTCTAGGATNNGNGNANATNGCNTCCANTTNNTNNNNGCATNANCNGNCTTNNNCCANTGNNNNNNGNNTCGNGGCTNCGGNANNGGNCNCGANGTTGTTATNTNNNNTNGNNTNNACNNNNNCNTTCNCANATNNNNGNNTGTATNTNNNCANNNTNCGTTCNNNTNNTCNNTAANGNCGAANNNTANTNNGNNGGNCNCCNATGTGCATNNTCANNNNTNAANAGNNGNNCTTNCANNNTNCGNCNNN
+
#"$$$!$$"#$!$#$$$##!"!#!"$"$$$!$#!""#$"$#!#"""$#$"$"##!$!$!$####$#!$$#!"#"!#!"#"!!$$"#$"$#$!##!$!"!""$$#!!$"$!""!"#"##$!"#$##"$$"#$#""$"#!"!!!#$$$#!#$#$#"!!!!##"!$!"$$"!#$!#$""""##"#"#"!$$!$$!"##$"##"$$$!!!!"$"##!$!$$!#"###$!##!"#"$$$$#"$!!#""#$""###!$"!#$#$##!""##"#!$##$$"#"#!$#"!"####$""$##$"""$$""##$!!""$"!#"#!"$$!"##!$!$#$!"$##!##"$"#$##!#"$"$#!"$##"#""!$!"!$####"#!#$"$!$"!$
@r1123
TCCGGTCAGCGTGGAGGTTCAGTNCGTCACCGACGGCGTGAAGGTAAATGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAGCGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGAAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCAC
+
.8;9036!!(9<..%%D3H36%0G=H*@1$*HD'&>7:C>$F;+@85+)=EA=8"24#99%!48.GB21=#+H-6&:6=C'H4G659"$<0@?FA?1:E'#BC6G.0-492#D&(DFE33F7*-#&;7@#5-))BH%6A<%9)B()E/':1C9H(587(A<,&<=#-<:$F<H/'E4)C+@H)A29B8C%#-&;3)2,!>D=*8-9164'?'.A92#'"/+F$8*:?(7C">2BB'9</$*,+!>G1/*>C48:='&7;A,?BA#=8$>F51H)6+&0*BH"H>6A<9%293#H*5A06>
@r1124
GGTGAATATCATCGTGTNCGATCCGAAAGGCTGGGCGCTGTNCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGNTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGANGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCT
+
@>+8+0(*:&)6H@39-"3F8+/#>H106@+/6-:'GB,D=H?*&;04,?6!1%*#;&/76+<8?"!.$G/(65DH5%C9B(A*DF(4D:EG#-1'AE))'@4=C:#H-F46E@&2:H00C-5.#)<>D2*!8+=%,(@"ED>BGG.$(")3-/?A"0'"!?#6-(?9E';@&<6>D,;475H4.%.;*$?71&,CG=;1>/C,","<8')"@&F5C3;@14*%<BG:.+1$:B2)&(1)-0H;?8.@:9;?7)3D.37/,F5<':/.-H?3G($+#:
@r1125
AAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTTTGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCAT
+
+<$</-4GB0@$5+60%=#)@A*C/@"?#51:*5>+D-+"B$)77!*A,55'/%,88%$/?20('9"-%&99*)=1D&.>-*!)=;B4=&!%F9.@
@r1126
GTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACT
+
BG#8:8()(<$7!3"B'A#1"#<DA/8>=A4)DH6BF+H/@64/=1'>?,:>A2DH7+9E/.-/>B</=>5#(1@1>><5E""<'074*$B837($-
@r1127
AGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACC
+
E$F?8'%+,#>4*6:3!B3A=*':1C;B</(()>57?=2#0?%18(1G3)-9@.>;0G.;F1H%(47+2%+$-41%'C6CC25FE4@%4+4+"B5*+D2%F!#84$%.8@@(
@r1128
TTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCAC
+
*->+@39;*/4<351(0?@H,E""22G.'1$>1=$)4C?=/&E!+>&<+E)(.GCC$'
@r1129
ACTCGCTACGCTGGCATTCTCCGGNGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGNACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAG
+
*5038:'=!41H!@5&)1G72E10%+/'77.*=G1=*F/,+F8<H"&3<*52<,7A,;;DE'-'$E@G"5+#<G)(C@C<&'-AB8'GH#<;++9//%6(@H2/<36"
@r1130
CNGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGNGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCT
+
&"E7)A#39F<B(!8:.,F;G,,478D0">%");"'B6#->>.B*AG(24D(?0,1?E(9/B;90;@1>'/G.5?3@<=6C3:8D>"%/E</@@(D59$$0!;,=:C)/$30*0,2,7-E"'D647BC#G.F9!"':)7>(HF'=:.%E-,D%D>=*,:(@9+F56H?3<8&CEBEE5<>3&-*6.(;'H";<2A@A$8"/F=;;@A8+;@*;7+G>*F*%4:/7-3B3>9<=45)"<7C:HF1"%D3-050H1<9F&=0
@r1131
CTCTTCGCCCGTGTATTCANCGCCGGTGAGATAANCGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCT
+
,1;C<:%<=>5,HB>%.2,:F',<<'>!(<H.6-A<,?%;32>FEG-7)'31=(DF?13F61,9:39:/D@:'1"8%+C*B!@8F;)'0.,><5:E85:%F$$A#-8@,CD2'H,/A-0/3;C*&&?4HC@2":6D249%')%D$?BFD57!$:E+6!.?
@r1132
GATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATAC
+
(."872-6@6%B9<9B@4G@;#-3B0*9:3;34.5444#11(.BBD#;7HB4;85@<=:#
@r1133
GAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAAT
+
*C-&H66G)31><21G!5E$=4F#&.'F'%H9=B+80"8G<FG2B.4-$-$%(!0A%2B0<%!8--98H';FF"H.+A0##;586++-%0ECB"&8--EE,B6'9/>%!(F2*1(:3
@r1134
CTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCC
+
4CF=9=*/.G1A0>(4C%!@!)F6G--EB#%E!G?4@+C(E@'?9=743=4;9
@r1135
CCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGC
+
/*,62CGB-*#%24(8-22&<=<1-(48%E"&7/#B45*?AH8CH*3;F$-*F9+
@r1136
GCTCTGGACATGCAATTGTTTTNTTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTACTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAGGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTT
+
=-/,.8.%1*&(>G>A:);47)4@>$%95<+>90C(D7)!8-2%DH:9A>90;>'22(E7EC'#7&);?*%/8&H-$4-<-2+H.(!54#,F8C7-?&>.H98-E85HA/=C-)*7</*<HD.%->&08EE)8>8((A&<A:7/#:D'!-":*A-B'H.@=BC)C'G&'7%!))H,&C5&0H*(G/=A'9!GC%%=H!D>B?%@5,@/C@EE:A5<=$0.#%*7H)4CG#1:@6@B3&45'=;B"0?=E*(6(GF6B'/F9-("24B*E.&<3:=+*&?AB>'6;D:E,3)*-8H&<4.!8.;=BB;6,H.35C6G98H6?H.28??9-69.?2"(;H228(?/21)G<3/89%!',H-AA*21E))0$?:-E#2="?#!<9.@
@r1137
ANNCTNACNNANNGNNTGNNNAGGCCNANNNNGANNNATCNNNNATCNANNGNCNNCNNNGNTCGTCTTNTNTNCCCANGGNNANNNTCG
+
"!!"""###!"####!$!!"$!"$#$"!!$"$$$!#"$##$!"!!"!!!"!"!"!##$$#!"$"!$#""!"#$$$!#$!"$""!"$""""
@r1138
CGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATTACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGTTTAATTTTTAAGAGCNTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGNGG
+
:B6!1+.H*-<&870H$4.8%";,(A8=*?F%'5"0:9$23B<"?067?>=)(?G1?=?G*=(A6%'$>2)-/-.D,'<"EE4A17>4$0#54HG(=H2==@;9@(C:9CG63&,H=)+-37/:.6?D/@,=AEC3D%4321%&:5%C=:A7#>=
@r1139
ACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGT
+
@,:;F@):B)'40'3(-=%>?%%=&C9',B7(#6.G/!G-5%<EDE<5"($&,62A!(-6,>*>6%>&.?>?,
@r1140
GCGAAGGCNGAGAAATCANGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTC
+
E(#"H!&)&92<B+7'49@<7<D394:2-$H;17GE-22'E6@!6+/@&41'D=)?)
@r1141
CAGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGNGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGC
+
3'(;B9:<%=?,<10B529#;))9)B0/9D/%2#3//>8FD9?A(2"."3E74>=D%,F,H%E.7CA3D&)!)7D95!=0'+":?22FF1$BDB:<>G='2:-$D/9HA3@*C)-7//G86DG(-HA!9**->.30.)4%C0-A*28#B:&"D5F,#,:/:<(54D7@$7:$<@*8C(&6#<E%+
@r1142
CAGGANTCCGGGAAGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGNCTG
+
&&'&$$))(!+(+$%%(!$&(")*(*)&(&&"+%%')"'+"+*'&')"!+"&+$"%'*"%!)*$")"#%))!%&""+!*
@r1143
CGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAAC
+
;@C45=C>%+D:"4?0=9$(.)/2GA+@+49)33.C1(*"#<1-2&;4?5"6
@r1144
TTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACNCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCA
+
CAF!)5'4%!*-5/>*D>)<C:/=";"+F<F68!H4:@#';2D;5B(/)2B-9,?423F!<$*A3;8/;4<>'E>>A)!'0C9):3";D2":*./
@r1145
GTAATATTTTAACCGCTAGATGAAGAGCTAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCC
+
=+)6.@/<#@"1*E<G+182-2B4';3#=.B;C9:<'%3?#0*?:'@-)38"8'5$@-GG191B();5@:HG3#B"
@r1146
TTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGA
+
%(+'&$*))###"+!%&#"#%+$)'!"'*""($&!#$&'*!+)"$)+)%)%+($#!)&'+$%'*(*&&($(+#&$%
@r1147
CTGCGGTCAGGTGATGCACCGCTCGCGGCGTGACNCCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGNACGGCGGTGATGGCATACGT
+
E)@!!!+D:F(!/:4!2'6,="8C3?>9'H"&C!)9@'&D"02"*+,@=5CBF8*=CF67*6)>9D&%)CG78C7-;"4-;=!'(4"@0;',B??.6#5F&):.6:B6B"C,2@?%H#:A2A/(!<5(%5:E*
@r1148
AAANANTCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCC
+
B?8%,<65/FF.?<EH::4@54,),971FA957'9)C1&>;.?F-4(2D&D'!.%7,(F;!FC25%8F>00A/$(
@r1149
GAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCN
+
+8!/(2E&6H)D=$!<D5+6&H3,C"0G?%0EH9H)1H415F!F2'<4@#2+>7HC)HB7>D@?H0/AC735%%CF::C<9"%&!BF"(!66'%>8=#2-&.>)'BE<">?G6
@r1150
GCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGT
+
9@2E.3AH>7-@*,;G58D#60G-<E!"@1%7>/A(8)FA6285#?%4F+9A>+5;66)EH69"'!9D8?2FE!$/,?6*@97D68:':+6=0EA,"7)>7>)&C&%H,C04:EG;2-C7>+>35;:9C<EA<AAACH7)1</(FG>+7'67'!G
@r1151
GATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATG
+
'+('%)'"%#&&##)(+)+!#$#$((!%)&$!&*$"!")*
@r1152
GNTGGGTGNTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTG
+
'(+))#!')#!$"!##)&)&$$#''*&$%''(#%+!"(%'+&+#*'((#!'*!&$**%
@r1153
NGATGATGGTTACGCCAGACTATCAAATATGCNGCTTGAGGCTTCTTCGGGCGCAGATCTGACCAAGCNACAGTTTAAAGTGCTGCTTGCCATTCTGCGTA
+
&56:"&)G)5A#7/=35,<7-%4$(#AD;63A<89G<?C=A4D'(+*8B9)514=A?()?+!)GD-34D-:GCC+#6)""<;#4*F8!+)D%</>A'H<:E
@r1154
CGCCTGCCCCTNCATCAGGACGTANCCAGACGGAACGATANCTGATGGCCANGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATNTCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCC
+
FAC>828(1#%'D5>/->+10<=%D0!7&,.'+;+7D9*B8E!5EA2!#C/#(>A$A6H;,8471,(3*B,.@$-8+4<$$90<H8;<H!!F)F/62%:,?;&4H@(?.@D92(+=2-A=<>H7/A?C+CC#58$<%;$:>/>(?/EHB3/%+:';&9:!1=&"<B'30"H?2+B&'E/6'+7DE,//A;89:(A47..?C+26&BCH@)2;(;7#5H<:?C&F,
@r1155
GAAGCTGTGGGCNTTGATAAGTCGCAGATCAGCAGNTGGAAGAGGGACAG
+
E67(6&=G=#==2E@'FBG5CE==,$"1/2=0)F(&B((0'9?"%/#:"-
@r1156
AGCGCGGATGNTTCANTATANNCCACNGNCANCAGGCCATN
+
#)(#)'**)%"$'**($%*'!"&'(("&##*#()!*')&%)
@r1157
ATGCCCAGCGGAACAGCACACACATGTCGCGGTGATTACGTCCGTCACGTTCACGC
+
?++%*>*."6!B%)&,")$#;9((:59:*"(G121H#'71GB44)?H:/62:;@:&
@r1158
AGAACGTAAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCC
+
B!GE2+9&A%9807>64!HD@9"E@#*?@&5D,@4=7$E,AGF=3:E=9,@=+'H126-$=?CC,*+'#"6<52$G
@r1159
GCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCGGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTTAGTTCACCATGATTCAGTCAGCACCGCTGA
+
$<"A9G+H>A&?F-!:976-/:(5-/;3=3#*9C2-(239"HH8?=A2,2/+7'HA+3"9=&5!36DC&*",!A5%8@6=1C#7;@)42$-,<79C%36@348H:7,-;?3(D/.E48:4
@r1160
TTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAG
+
)A)!&%<-,29%)B/0+3@<,E1/F)A7G1$B2-@9;->B<?2(B!A4>/=/#69D3D!H%BDE>?*=+";F6)@E?8-FA55:B<2>G.4(34
@r1161
TACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACTGGTGTGGCTCCGGAAGTTAACG
+
748$4EC>BF503'E9>-.3!1/!*67C/2)3=A.!$HE'E#<F@><?G"GB=(E*/@(%%45>8"$DHD@F6B9!+B=69+D77!'(5<40;,GAE/"?6D..=';$>>GBAFA;G43<D7B1-A410",$&5,6('E-&?G)
@r1162
GGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTATGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCG
+
+"%''+&$##''")%$+!&$'$*'+!"'&"()"""$%&+&##*+$"$*#&)'"%%%)&+(!+##%&$)&$*+"''##$!'##%*("#''(*(#)(''$*$+%#("##"%('$)&"*%!$*
@r1163
NGTCATATTCNTCCGCGACAGCCGGACCGCTATAACCGCNCTCGTCACCGCGATA
+
$84D%E6@&!!*3-9#)G6AH57DFH?8/B-<B>G'2=DE>.B!80"?4>@+5DF
@r1164
GCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTT
+
6)=/0$F!7,FB<+(&/F))3"2?=@H;D6H6!C/)-(,=>G:;3-C-*6"(E,C<#!"=)$0F2>
@r1165
NTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAA
+
!+***'!'$$#*++!$!$%#$*%+("+%!#$'!$''"#&!"%"''#()'#!%''+'(&%+#+
@r1166
CCGCACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGNCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCNCCACTATCTGGCGANCAAAAGGATGGTCATCGGTCACGGTGAAAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCG
+
.F.39#0:.6FHB%>H7@F4?#(++2EF4='%9=1FH3-/33!@.A:!9"'GE-+0%(<9<B%+D7B.(9<BF?=G3%!<%69G:'(;87!(57%0C8D67;@F)=AF@3'&G6A8))=A95,)/BH=*4F9>7<:G+H@%%5("G%'G0F.C./$'14CH@=)D#'>4;)=/5!"*A,FE06(C+#)@'B;("
@r1167
TCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCG
+
-*.)!2=(%DF),>39,:)*33&8-6(>5'1H0'G,!',?E922(5/$;:"5E!6:7.%E1',G?#:,-2,?C#A%??EG?@*%3C@H>+(.243-
@r1168
AGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATA
+
@&!,)&;C4@1<.<3,AA,"56:%?<$'*;A##C42DGC'$G7F5$A42;B(",=+E+!H>B;%)EA"+)(.8,/A*E',;$),F3+F:74;'<02&=2:$";(D$198)?/8E)-(1,&*'>A6)$DB'F$+;,6?)3.4H##H=A5.8*C-DCB%,<9@0;%235D,6"<*+D@!=*;B
@r1169
AGNNCATCTATCGGATNGCCACACTCNCAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCAT
+
'%!#&+**%$+$!$+"($'#*!$*'$'"(')&#'))!(("*(*"*"'&)())&)+#%"%*""&&"!"+'(*
@r1170
TTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGG
+
'6#/&'7;9<%75%.@6)+,%*?3;(9"?4#"=!=B#,%$@CB%4/>!??%C)2+?A
@r1171
TCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCANCTCCTGCTGGCGGATGACG
+
+;0@;0;G**C3AE!!-74,B+!*.?(=/9H.#2@F-4/2H(0!?#4>7'3B!H"<#GC/-?
@r1172
CCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAAC
+
$&%>6*B7"ECH89=8>#D)*7!A)F$:8(C/A2+!2!#@<,AC+/"5.@F>-*,1&-6/<%F-9:41.%&D"32.-<65/3H5G@)"A0,?,7
@r1173
TAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGT
+
9$3""<B9:%;!116E=H<=G$03G>,),.8<%:>:+A=!HF!4!72;(B<D+#+:D'(%63,"C-"&-53?=4G8=#6$96/!)++:&+0F%!,!E:&$9>&@701!!---G!0?@*+6*
@r1174
ATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTT
+
C7#5,770)$+<1G*D.<4+09D9.@'0.)HA?C:DDF80<5"4)B.(
@r1175
ATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTNAGGATGTNANGGAACAATACCNGGACTATCCGTATGACTACGACTATTGATAAAAATCANTGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTAGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAATCNGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTT
+
*:C@@%!0@.,G&#.-(6.?74A)H@*>H;5';#7!"+%'"#"<B23;"&49;)94>,))$45!,"40F=E4B=!G%+.E4/=(@:+?@/8=;%";;9(6$%(C5"-)$&G#8/#0>C">>(),HD1>6,"4/0+<A*EB@5-+AC(#>.=!4'"/EH"G6<%@1#E.FB%)<!<#8*+$$C9+C6<A(DH(CE74@=!"083.=:?H;69%<+E-05>D1FAF%=8&;3+F1*2D.8)=.:+,-'*:HG"()CGD-,3H*5%-*%21%?$3.&A8G!710A:0.$3A<D8D>751D9B8'A<"?41HG93'C!>FA
@r1176
TGNATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAAC
+
(,/(!3,?'?$1F*D:(///:7G>#G2(H%FG+=@5'.4%
@r1177
TCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCANGCTGGCGCGGAAAAGCCGCGCTCGCCG
+
E0/;7&3;$C'DF4H"A%>;;>%.BE5:C"610:D5-0!%90-5+61@'%H@F,85DG6&,46H)@4"G)(E1=?($%=?64;C5E47,:8>+H/.$0*G)E8"90)2F26&C#FFC3<6!HA0:$0:&=.2;0:3)>91BG<@1E(=)#"(:B:!5>@?#,0<<,8E?C
@r1178
CTCCNTCNGGGNGGTGNAATNNGNTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCTCATTACTGCGGTTATAGGCCCACGTCTTATC
+
&''%''('*&'&&(")(*#%!'*"*%#)%)%('+$'%&)"')#&$'&$%+%$'%#)*(#%)*#)'"+!#")'#)+!!!#'!%&*+$!&)%(
@r1179
GAGACAAAGGTACGCCGGANACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAANCGGGGGGATTTGCCCGTAATCAACCTGGGTAATGCGCGGGTTGTCCTTTCG
+
BA.4-G5*1><4".0@B,FH69<G<C:$*B46(C,#8:8+9;56C&%#="25F':.8*C%H,2,DD8:1!D:BEC0E#>*3B4:3"1GF;/C+!FHG43+:8B<E-1A%%;?:(;6420G6/?0#A+A+&-0E91G5<1.(
@r1180
AAAATTGGTTTTGTAGGTCAAAAAGAAGAANTAAGCACTTATTCATTAATAGATAAAAAATTCA
+
GA3&:75G2<D?<,2A)6A-4"%8)G@,(%!?(?:9<C)%<',2HF!(8%G$#DF25D8H''.'
@r1181
AGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTT
+
(2%99>4%%C&F?!5A$89&D)6E92?3F;=FC37/1@-E/7!-&<)=H>.3GB3
@r1182
AGATTGCNGATATNAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGNCAGTATCAATANCTAACCGG
+
$&**%)!&'''*'!'(*'+&"&*""#!+"'++(+"("+&$'&%")%)**%(!+'+%++%)(($&)+'"$"$&&)'!+"+'&*#("+'$!)
@r1183
GAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCG
+
#*%<=E512%0('@6-G-34'%-0,=+G)5=G9G;1,?7?'(F-"4!E0$A-D=
@r1184
GATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGG
+
>7@8:0G3D<>&F$05BH?&@&$?&&"#H1"?,=3#0@$8&97/B>:.H@&#?C*&98A>6<"H-:#5?5?+>4CGB0607##H;D$A,848>04"5'2+!-(H58G;,F
@r1185
GGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTNCGGCTGGTAATGGGTAAAGG
+
5H1;AB/21A?$A?=((5H4?+*(2E01+.615B60;:H*!*HB@3>7.5!%<';&:!
@r1186
ATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACC
+
E)4!4A/2E*;C(<B-#H(6+=%"3-D*A9"D*3H'F<2(@<D?72%*8#**///,%0
@r1187
TCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTACGTATGTCGATAACGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTCC
+
H33#+5?-&:8)D)%>B+57F$2&@A#&<8H'795A<G2)/7>.4&6H'(;+AG3*F/GG9*A"#1GA%73<:,!#'">F!)CF$61E=*<%":@92:/>%A>#((!28(+FB<+BF.+G3>3%2-#*,828=<+.11',&323.$5<?3B6G*'>76A(730(1#<(!?<4,,B#>>0B1*&#/5A7?27G&:EH17EH95+%*%A'ECE*%9F(@0E?,+05%4=+=8/>>%5?B.*#C2AA7?
@r1188
ATAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCG
+
&""3D#)F)*E3$$F7$2A'A?H+:EB>/(!3E"G:93#1)7-<4A
@r1189
NCNGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTNGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAANCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGG
+
$%*$+))('**"+$(+$(*$(#"%*'%$($')()+''"(!"(!$"%#'((+%%!#%"$&#+!&%"#)$!#%%&&*"%"#&*(%)''(#)#$#$$''*#*%)&')!(*#"+$"#&&+"#!!#)"()$!'*"$'#$&#'(&!$)''$)!!'!"$("(("*
@r1190
GGGAANANNTTNCGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAA
+
$%'&)"$#"'"#$&+)'!!"(+)("&"))*$!#%")"+!*$$#%*)$#"#(&#$!
@r1191
ATGGTCAGCCCGAAGCTCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGT
+
%C:<,7@"-.%$/#>#((6#A:7GGAAB0-H?138669,/C:.B"438*<6'>5(#/!:BBG-+F,+71-(C"4H7A!%=28&1<H.;"D?""B<:%8.&B03@);"&#H(>:DF2D%CD.
@r1192
GTTGTCGAATCCAATCGTATCCAGGTTGTTCATCAGGTTCGTGTAGNATCCGTGCAGATCGCCAACTACCCAAAT
+
&%)6.HH7>-4$(EH9F1=@"+%2)799&:D+F0)C"F57;%-C65(:E,1DF(!G%C>'=10&;9#2;9D?>F4
@r1193
CTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTG
+
D:($A+F$=+;&6/+C.57$02323335C53&?A@>-E51H+%6%,1?*"B?#1;C0"G*$67)H-G2-<((C2
@r1194
ACAACAGGCAGTNTCGATTACGGCACCAAATCGACGAATAACAC
+
<)*005BD<9@@B"1</=86H;9-+GG<)1)H<48,-/9#:8+>
@r1195
GTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCANC
+
4&)/B'H*1=6&90="F"!36>$/B/,/"'7/)))H%.GB,/%"%@).E&)D42D&H3>H7G(GB%?/!',@7!2)%)76,,>H-C&48.HC<?0%G%6!8'3!,9>$A?@2%#D2C#(&"<0/H3/,**-17$:8:D(/F2"7>A?FF77/B8:9-A@A&AAG>
@r1196
GATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTC
+
/**1<AB"0-4#A>#--,;8)30;12.!/97(G>C!:C4=0>9/EH:&H$3($"9A.+=(A;
@r1197
CCACATCAATGGGGTNACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCAT
+
+C=E)<*<+/7H%G)#F3$4>3G!."C."F>:@56).E!H.F1=6B?D"(<2!D'.')F8
@r1198
CAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCT
+
8!G/.0((!2'&FH6,@43!;2#(D&?@:HB&,5"CE=%479"HBCD2$>GA<:F,(H6,%B*',C!(!0,,H7#'5-)"
@r1199
TAAAGAACCAGCCACCGCCATTAAGCAGCCAGTTATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCT
+
0CED8$+71%=.0;.:%E0085625/A8*7>+(=>A,(.&"72)(<@#-0D.-9,787.!;19%4<&@ACF493"<.-39975)(F/6!7DC:E@E->9+
@r1200
GTTGACGGNAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACNGTTCCG
+
:>).+-!A)GAH#=3;(=:D3G@<447(/"?EH0CA$):1)D#27H#FH&8F"(D.2HD8%8E<>"B0$)6@@4="@>*=>11=+?%!)"..G'%??@-7%%9EH$D72=&:.*<(E=%@(@29G-6(/8".>,=>-(C(:F!/(H
@r1201
AGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCNGGCTAAAGCTCTTGCCCATAAN
+
++/"%B-A>F+'18&=0?44)"8A;&BA($=%9AB0HF,1??/<)(E!C=:7DF@(4.2D2G0:4--&!@391&6"-,#,!:,0505,.3>836/8G:F?
@r1202
GNAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGA
+
9C!H;*'+*H<4/5&0H*%-->@0#0F+@FH-5E6)/*1+G;H.=-B?H+.H9#30GAE?FA8='A,86@
@r1203
NNNTNCTCGTCCCGNCNGNATTTATGTNGACTCANCANTTTCNCCNATNNCAATANCNGGNNACTNTNNNCCGNCTNNTCNNNTNNANCCNNNANNCTCNCNNCCTCACANATATGNCGGCNNTGCNCGCGNANTGTNNNANNANGNTNGNCNTNCNTANGCNGNTTCNNNAANNTTGCCNGNNNCGNCAGCNAAANNGTCANNNNANTGNNTNGANNANGTANNCCGNNAGACACATGCNNNCTNNNNTGTTN
+
$"!"#$$$#""#!#!!$#"##$#!##$!!!$"$$#"#!$"$#"$##"$"!$$#""$!$$$$#!#$#!"#!#$$"$""!"$""!$!$$"$#"!!"!!$##!$!!$#""!##$"!##$$"#$$!"$$#"#"$""$!$$!$##$#!"!$#"$$!$#!"$"#$"$#!$#"$#"$#$#""""$$$!$$!!##!#"$##$""$!$""!#$#$$"#"!##"!"!#$#"#""""$!"#"##""$!"#""!#$$#""!##$$"
@r1204
TGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGC
+
&<.7<:8>D>+G6,858,?358)G<#"BC/F28&H!A:+%A>,E!121<D=6B!765;H!F32"7*=2:"!%?9?B:"+HEE8"0:@48A!8-E"*AH-&2@@"%#2D>&B46,AD.,)"G/&>:7<G8BD59=(-=H)$&;B68?+%<1>7%/H4(,01";;.;G-=+1:
@r1205
NCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCA
+
(C8-(5"BE09"!=1?!F09$*>5+6H*/:F5"74D-8)90.GB%:-
@r1206
GATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTG
+
H<D56?&073,A/0>"93,(.F-D-(!9*@E)7"1,3B")C)8CH**%>HG65.>8/$""4$'D=.50H3*G9D(3#1$;"A63#+8<
@r1207
AGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCC
+
>.0,5A>3C'CFE9&A6878!F%0/3=&%8*!'/#46?8."&9=(+@#%
@r1208
GGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCACCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAA
+
4H*C'&$F4E6!5=A&EA>5)G68$@@D6$F3.!,)!!E=*8HB484,@++<#4"%;!#:.,6E=2*:/F9H4?<C+B8,#41@.=87B!H3*@+#./68+!H1+:0<!*E7*;137+1($%*EABH$0H!
@r1209
ACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGNGAT
+
D0=F86)#6'5?);F-A>9:5/A;'FE3,A6%A425,&B/?$BC=#>'
@r1210
AATGAATTCAGGACAGACNGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGNCGGC
+
0%:13.A<*>%09CC0$B"E4?H)"'H$/=;?2@#(BB;(4.E#0HFGA!:$3H;)))1,
@r1211
GCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATTGCGTTC
+
?3G=9*F)"6)0@:E@%H)?5-)4G,=C</$1=6-2#8+<@7FC>21C)6!/D
@r1212
TGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACANGAACTGCAGTGCAGGTCAGTTGCTTGCCA
+
@0G11FG'.)F!@A/).%2.#D,79#:H0=)$7H;6H#E4.-/,@""4!2<C***B"B91H9*9:D7E--;4*'<%A008**>DE*,$$3?5##=?<'(CH2.C*/9"
@r1213
NGTNTCNNCAANATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATANCACAAAACGATTACTCCATAAC
+
#*"$'*$'#$*)++)"+&*))*$$$)#$$!'$)+($*''&%*'&)')+%$+)'"&)*$#"($+*""#+*#$$###"&&""$()&#*"+'""""')&''('!'*'''(*&!#!+!$""+&'**
@r1214
CGTTGGCGAAAAGTCATTAGTTTTATTCAATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAANCGACTTACTCG
+
1F($@!<2'#779/C7#A)!1(G36%=0";H+C93(B%C3@>G02<?5A+4B")):?/5E/6E<61B1<:2*,!%,ADB50H=05D063D*D3:6:4*
@r1215
TGCGGAAGGTTACCTGNATTTTTTCAAAGGTAAGATAACCGAA
+
F"+9'*,07)=5>7G#/;0,<1/)!,9<D.#1)ECA=-@0E&/
@r1216
CGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGATTGACATATCCCGGCGTAAATTCCGAGGTGGAGCCGCCACGGGAACGGA
+
$6C4HH&08$?C;"55GCG!-*&%"4%-B)"?:A>9"8(B('C*7:D)7:100F)D-8(#8,B)%;0FH1B@2.1(3A?H;24?8050(57#@;=$@4&(@2.,>8?
@r1217
TCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTCATTGACCGGCAGATTATTATGGGCCGCCACGACG
+
$H1518#10/'25C><17!5,#>2)82)0E#=.2*/'=51((6F1*EH5%;88H.(.&E#3:(4F*D&!A'46=)(0+A/8@1%1#@+,/0!D4A:<-<97=
@r1218
NACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATANAGCACGACCGATGGCGGGTTTCCCCTTGATTGTCCAGCCTCG
+
'2F%;@D;B,>3;#'0@"511D!%%+7H:")(C3>62?3)"8G'&0!=.@$@'?8:=$6,D&#)C6C8*;4;=&4&-"B:"E%'>D@/#,3G=E+A(E",54C=3"C/&15/$A8#EG.3E,3'3C5-@C8
@r1219
CNTTCNTCGACTCAATGCTCTTACCTGTTGTGCAGATAGAAAAAATCCCGAAACC
+
'!*""#+)*#!#&"#)+%&$!!%'")("+$&*)!'$&'$++!*('&&$+$$#+*(
@r1220
TTTGAACAAAACGCTGGTCCTTTCCGGGAATCAGGCGGGACTG
+
+#(+*'%*)#&"(!&&%+&'(#+*'(%*)%)%%!$$'%#(#)!
@r1221
GCGNTGACTTATGTCNTTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAGTCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGC
+
'&!#CB@H#1B5G/<1C''1@<@FE+$2$?:&F!@-+CB!CCEG>158B4%!>E4&"'#,1!C=//9+!+0H;>9%"&&%,@4,1F/.+'+$12H=.(E(7%">8!H4:<AB1,4#&5*=8,B44*!$+=82#5,"E58AF($C@(F+$%!:8G;'7;=)@
@r1222
GAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCG
+
F,'G#6>5*92!B!6&&F)=B77/%"G7(:G2#)&8<:C3!C&261,3?235#4</",!.15E43#5
@r1223
GNTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAANTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACNTTCTGCTCTGCGGCTTTCTGTTTCAG
+
&+#($((%*'"&)#'+##*+"*(#!)#%#&'(&&!%$(+)$*$*%*+**)*&("(%'&$#"#($('($("#%#+&++"&$'+(!#&&#)*%)!!(&'&*%+%$"##!&+!%#%)!)'''($$&'')(()%**)!*"$%*'&!#+'('!""#*+*)"(&"!+)"+&
@r1224
GTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCT
+
=)4F+9/E-5&,H),'-">G!8-B*,'49$?<C96'>C6>H@)+
@r1225
CCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACGTACTGTCCGTGGCGCTCTCTTCNCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCGGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTNCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATG
+
)@:7AB=0'$(;66;DA@CB/.F)6?26H,.+%6*=F?+>:,8"A&-!#%4742>@$+28HG%:3(5C+(0!0-.=/./,>D2EF&6+)B>;.2?1:529$F:/0A2=9C.7,H664C%)<./?$?796844((B&7F886<.,;6GG?2)#8D."C!7A6)':F+!;DA$E$E$CA%@H+8=A$;@$H.+2+E$FG=0C14!1<)H!;/)6GC'8#"97BG7,H7'A4,%G%<G4G+232H'6$@3B#-H+:(/9A5$(D13-4-@:4:+=/H2$(:$7F@$5;,'37/D
@r1226
ATNGTCCNCCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCG
+
($&*$$(%+'*)%'+'(##!&+(*$#'$("+#$*(#$('%#!'"(&"+'!)&''!"'$#*)*%'&'!()&')(($%#!!&
@r1227
CTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATTACCGCAAGGGATAAA
+
+67='@)57F5E:--()C#<23)6,9<>+$)B@'*@'2A>?HG8D71,%&354'<64B$D#@(03#)A+02
@r1228
GGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGA
+
>-3.;A@$*-1EG'9A'9B+,/:2;.?"@H7+,$031$G*5377/EH!,+5".)$B6-9&=B&'D).,E,.G8=<9*5C?'(($/#?(0/91%8-*0D.7(62C*89
@r1229
AAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAA
+
4*65/8H,E;+F+G$>$)%G8)7>4@A,'@2(<03:;G:.+6'B"+HA$6;EB4+5.(199.H2,"6%,,E&'00.$H1&(#//A:>#/";(4E$A:AE
@r1230
CTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTACAGGAATTATTTTA
+
B$0(61<!/!,B.C7*=A$3)*D<%C!(@.B=(B&GB5G&,239#.D>C5D;"0A$#4A@::825A9H4&#.08#*
@r1231
AACGGGGGCTGAAGCCATGCGGGNACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTANNGATTGCCGGGCGGGACGTCAGCACGNCCGGGTTAAC
+
+##1<B$.5&4!@$EH+:/GD'&.>F214B$3&'A"%HC0!-94!F;"20H-/1,9(B%EB/-:45B&2"+;'D170A)!9:;";C8.0?90FD&G,F1A%,6A94(':*#*/%&;E4)=
@r1232
TGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGNGGGG
+
(B2%('(C>@H<D&#C,(*'*A093'0F0&C-GD"*6,*10!-G<690EB:(%59&/:.B2G);F;;E$)@62;D>?(-5F
@r1233
ACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGNGGGACGTCCGTCGATNGCAGAAGATCGCAGCACGGTAACAGCGGCAACNGGCATGACCGTGACGCC
+
+))*%'$+&+$*(&%)))!$!'$'"!*$*(+("+&)!&+&'%++$#"#!+"%&*'+##%$%'&*$"%')&$'(*)*('!%"!"%((('('(&!!'#*'&*)'))*$!#+(
@r1234
AGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTA
+
41?E1D7'@34!DD#F@*13A*/1H'H,#=9##A(E.?;F2:B2;+'$7-:;G713CA2%:AG2<>6/0#1E0G+.>-=;-;?!%#@A1GHC%(>'6E*=G14:!E$9))/)>#3;/&B!:.#$5%%@,B#&,1*4E76;:B='0(<4!CF<;
@r1235
CTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAA
+
9$'H@=:@%,&/9;,->B3$:E;<):#'H9!F/7#FG2?#!6B?D&84@#!*+3?+E"'!+=H<=F4E9,>E.8AC#2>8"=417)"8!)5;C@@('/0A
@r1236
NTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGA
+
"8!+5!!%'.,=,F@:A@'-D>0$5:E>"0.=G&).!&;1G><8CC%7G7F@/C-/8@'=4<#;+,H+=H+"7G!C+D!AD-?HAG?<H%,96E%
@r1237
NATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTNATGCCGGATGATGGCGCGGCGTTCCGCTACAGCCAATN
+
+)#(&%)!)$"$&++#&++$'!'"$!&'$&%+(%!&!*!!''+&(!$'!'$*&'*)#%$"+)'&&($%+&)++"%"$$*!")+#*"&%(%$!(+$(+*'!#'!"%!(*'&+&$%*+)+
@r1238
TGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCNTAAAGAACAACCTGACCCAGCAANAGGTACACAATAGTTTTATATTGGACTCAAGAAT
+
?(2+3G6G9D>BF&%*;#E6+7F+$/0>,FA=7@</B%=4(@G%.;11,8,?<#39775284'"-D<(DA153@0G*?<326G:!('!9;*1H)3103+<
@r1239
AGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACAGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTAC
+
=2F(*17!B!6BEE+9F0)&!,40F*2B2,GD4615,":,?1<=FB7('.'B=+@?C8H3#/)861)1.FF5D#3D&67F(@1(.F4'HH;AF<#HC*;.-%DF?,52G2!!"8B4FB>:-$*49)2=B6A/"AA?+'=<4</68"04"')G8&E4*<#)"F6,41'CB#5,.62B*>18!2A92E3>=34.=$&9&
@r1240
GCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGC
+
+":HE)C.9&2=(21%A<E:$'2!!:89A6F0<<G>*G@E:6%F'E07FB(D*G%<<E
@r1241
ATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTGCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAA
+
-CH:5)3H.=<)/!6;//#=;HE*)9E;+"%1DC*+@2,F=G/@&A)5(A;;*"(@<)5;9.EA>2AA44F088?:CH5D7G101,)@(:.C&6E43!H)GB,2$A!6D<;)0C47'EF"+>9A*3@'.E4F!!>$783H7;C#
@r1242
ACAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAACTT
+
/A=&%2?3%2"/<'9.6:7C7,@2;!=8'E<4,#?8#5<5@7=,F9C8
@r1243
TACCGAAATCGGTACGGATNCCGCGAAAGAGCAGATTTATA
+
B19>*+@F#6H'H0/=?-,!C>#-:=*.C=@C37C?#C2"B
@r1244
GCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAANCCGTCAGCGTGGGGCGCGTGCTGGTGCCTTTGCCATTCAGTTCAAAAC
+
)?)(E4EDD2/4"@:C&;6D49#CB0$E/D5?:3@)@;%786;4*:==8CG34#D0"1"=!(:@H&9%E$/+8D=,6*G"8/#,,.)#"/%@.
@r1245
GCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTNTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTNGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGANC
+
.D;C,0*74EC%+B6A:A(-DB5622GG6;/'6G9/@%:H:>1D00#E=)>,4*),$%===085>(266#2*9F2,-,.6D4!65:G2>F26?>6/H60;.8E786,;+!'?5/4D9&#D4G>772>D?FG:=:.&!04,0.?F:#31<>DE"=*A8ED>7*&#84,9D*/93:90;@!>5%A.'93204<6G;1>-*F-@B3C*<&%.?1*35(!7)*$C+?24#1%?7$>./B#?$,E*/!4CF*0*=A*?DA*E@7$?&#<B*,&(+)).'<!?0.2(/5?G''?&)%B1).C%"/7;H=,%@B?A6"@D?"+'3#:C@/HA#%B9=2"B8B8H9<>$.-$B54>'G:,9F)A=07=?+/B)<%!"
@r1246
ACGATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCT
+
'#!+!%"#%*+&"!**''"**#"&$+!)(*'!&(%*+*"*)%(&(%)*#&'$$!"%)("&"&)&#$+!%&$*&*%%*'*$!#%(%&*"#!#+*+"()'+*!($$&""+!**+$&(("#)!#$+(!#
@r1247
AATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAA
+
BG1%5$84%>FE+#5635,0G5G89@?B-7B3;((+8"G<A3B8?.</4'(0?
@r1248
TATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTGGAAAGATT
+
89*A"=:E>()F+0)%A7?F2@:A2$?#!&75!.>0#?.D=,E25>1/884!'5:(=<)&)8A
@r1249
GGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTG
+
<G!)!CD*%%4;0D(/;'F1E7$G"=7G!%?%>8!#,+%/E',26G@/+?<=78?5#'><
@r1250
GNTNNCANANNCNGCTNAGNACTNTNANACANACNCCNTGNNNNN
+
$!$#"""!""!""#"$$$"$""#"!#$#"$$$#$!#$$$#$$!#"
@r1251
GCCGNGCNCNTAGNACCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTNT
+
*&'%"*(()"#&!'"+!'%"!'*$*$""*')%!&$&*#*#%+$'#)&#*#%+!"+
@r1252
ANTCNTAACGCTGGCTGGGAAGCTGGCTNAACGTGTCGGCATGGATTCTGTCGACCCACAGGAAC
+
(**$!"%+#(#++'#!"$&*")*%''$$)(#%*+"+"&&($%''!()#)"$")+%&%+%+$"'&(
@r1253
TCTGCGAGGCTGTTCTTAATATCTNCAACTGAAGCCTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTNGTTTTGGTAAAGAGAAAAGTTTTTCCATCGAT
+
F'4!(0/+(*3A#8B2?39*G#>7+3?7*&BD"*/9>>-+%@)!GH')=>#$%$/-.;4.*:#!%16HG?)C,+.*&AF"97&8(1A0:;7H:3D,'1G%B&.47F)
@r1254
GAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTTC
+
28.1"*H.9/.+E).&++((/D##7>*2;'=55$,8)F</CB>,1%''8CB3>(
@r1255
GCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGGTGTTTGTGACGCAGGGTAACCAGATATTCATGAANGACGT
+
D)18'*D8>$'&:504)$#'#/%H5@==H:&:BF:%2CCG68B!.D@3(%?*98$",=!%$'FE0?-"+G"5++E+8+9?$778@3FCA5"&-C;C7,9C5:F$2,<%94%B=6@44%$-8E7EH(=+H9B?-)8$<?<A86D$1D9E+A:0'5>)A446E@9**+;//GB&H>
@r1256
CAATTTCAGCATCCCTTTCGGCATACCCTTTTATGACGGCGGCAGAGTCATAAAG
+
*DH8*13@C7A&7<+;='@E*:"G605$%?G)%8':)B-:2/7%&&D;B&@1,@;
@r1257
ATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCAGAATACACGACGATGG
+
:)",+.!H,HF6A4E'"!G8/700:E,<894-+66916.9-E'CC@5C/&@9E:-+0:#9E28C:E1-H$1A<;C31<9!94H,E6<HG6!/3;&-<F<)#!!E!F+86!
@r1258
NCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGT
+
$G;A;46C.1!1<>:!"A#";1%7.HC;G<@+4A1%G%163+)!5349%!2
@r1259
GCCTGAAGGAACAGNATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAG
+
*?@4,::%B,9"(AG%BDH/,1BGH,H8/>'97$D(8,4>-??B)01D%?<@0,!7@*H*?1=)C)=B<7&'>?3*7F#2A/#,>>C%+-HF6F";'?>!?;8=,!B@
@r1260
GTGCCGGAGCGGACATTACAAACGTCCTTCTCNGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTGTCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATAC
+
<3#+)+.;3+4,#E#.:G!GD8+%3%%;<=B+2D$1975(8(<%-&7,%957,'5=1A048&/+.G,B6H>&$8<44</A?$;&>'22D70"?0D'1$.:':H!)!B#&D@<(EC#4:.(5?!@;@D!<)>;E&F#9A."11@&.F7%%>#3(F,$H-+?00EC$-0$84C9'8G%2CDC=H#,*3!;%9-314E>,F**C00H1-@8#C-557GH*G=
@r1261
GGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATAT
+
/G,$(%!/73C?*FDH369.&D"-&9?@@D'22)8,7H!,736""+!)$9#%:D4G:H5CA)A<(E6G"4>2#1'B!CC
@r1262
AGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGTA
+
7+<"@3('0C(.4)>48@9;7?6$F?E>'!=++<H+4)$%0*@F/4?0F8"4!'>-#.DE648=HF06>&A/$E"@FD0+?&D5.*6*%F"&=/EH;.$-;C2(?2=:%43AG?"#7H0,2(BB3"BH4-HF22=<DH>8D#/%DH3$.(3
@r1263
CTGNCNGAATGNANNTNCCNCCTNACNNGGATGCGCGGGCNCCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATNTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTG
+
!!("(#%)()"!$'$'!(#(&('&*)"!''*&***&%%**&"+$+$*(+'$%&#''(""*$+(&'*&*#%')&($&#$"#&'(*)$"!*#')"$+&!!'"(#'&(#)()$+(+!%""+'+('*+$!!"''"("$))$**$"!)+*'
@r1264
TACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTA
+
B;-4,(5?7=.1E.-H-D-0E>.4'41B4G76.0/%C@$G>(+)2"!1H<461./!7B-8H>>C(:E6<$'=2C7BA6D7"'C=@C!BH+-F=B)@55DH9)+?+8E1?C%'+FG+-?%
@r1265
GCGCANAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGNGTAACGGTT
+
22?>EF<$H@4A.@)%&)C2*B,9.D."589@:E?C7=:*@EA#55=:+F4!A4$2CF4#4A-$/;"=B"$E!55$#'4*/+-5@6(H07(D9/!H,C(3;#G5!C"6/6%,C>H7'$'
@r1266
AGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCATTATANGCATTTAATGCATGGATGCCATTAAATAAANCNCCAACGCCTGACTG
+
'D;F--99A<>?H20$&@A10=9$*))7E+@:'/7D114DGA5<BB8%(/5$D-9!8+,6$DB%31E$81H1C6G!?D6$@'.C8"-/;@6$<">C34(*E07#8
@r1267
TGTCTGCGGGCGATCGTCAGGAAGACNGTGCTCATGCTGCNCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAG
+
2B(87,65,,(2A1&4A*C:EFF>)"+8DF'(::>7!77=%F.<35?(84A!+2#8%H&D#4F#'@H"6.4'D+.56A9E?!A(-&@>8'
@r1268
CAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCA
+
F',6BD../4?2@9%/B0DD%+?0-))8D13%@=2E%7FG<;#).+%*6
@r1269
GGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTC
+
3+H<H;!33C?<"?F'&H<8($+2&.F%!F7':;'G6=&/(=&>5D#(,E(0B.38!!/*+-/351)@".&3===!/(:-F1CD@64)0$4(-4H=5F&8/16=E?BE&)=F.$B8,G+"6F<;/B(E;5!-3B
@r1270
GCATATTGCCAGCATGGCCTTTAATGAGCCGGTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGNCCGGCGACAGCCTNACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCA
+
5#G:C$(1F,,0E93,0EC+.9H<=3#%:CF@E/,?BFD#H0!%?$8-#>&71C?1$)9?,7=12;?4,B:'2B2AC2>3'EC)&C';H66*6ECG5,HD';HED.G5B@"*FF;8"4##GH.:8?0HE-0A;!DFA9263=;@8<*$5%!%57??35313#8&(EF&*@@.-5-C4=87",'2-:2>A8=,$EB@)
@r1271
GNTTCNTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTNTTAATGCAGAATATGCAGTTACCAAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCANCAAGATATCTGATTCCAGGCTTTGGCTTT
+
!!$)&!)%(*'$*+%'*%"#$)*&)!'*!)*(+(()##%+("'!##+$'#!"&#%#'"'(#'##'+*+%)+#!"(&$'$"*!###!($'!&"+"(((&&"*((*(()())+%!'()&%*($#(#*'(!(*&)*##$#!+!#&(#($**+&!#)#%+)$!%)(!+"*()'*)$'&*''""'
@r1272
GTTTCACGGACCTGCTGGGCAAAANTTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCA
+
'9$G-$7C>*.42(->><D)$"*@9/,@B1;$4/?)!;.)&F3=$E)/5BGC?+=3E7-;>%'D>H>(DC(%,GH55+@(5="D"3BH0$0F./-B<63#<?7./+(5$#/(A&?(7>H18B$
@r1273
GTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTC
+
/!"512"#A-@8#5=7?>">&A@F+7-=>$D?.?;5-,;!7($&06-A-3E-+@BC>?1$!9,A#2188:;/"
@r1274
CTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCC
+
)88"DC5F00<%>=.5C29@!(E";F;<3.B!*0F?,+G5,?&?ACH$97409@C1
@r1275
AGAAANAGACCGCGACTTACCATGTATCTCGTGCGGAACGCT
+
5&7F(!(E.(#+1?,&1-@F0@32.6E6+7#%!5*+?6#%8E
@r1276
GACGAAGGGTGGAGTTTACGGCCACTTNCGTGTCTGACCTGAAAANATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACA
+
(G*<(67>7F3$$77$5/)1;F#5$-?E$(!C@96(H:B64$0'54$E<@B/#,F0+"E6B79>-C=$F6):C*@3$B!78"+
@r1277
NCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGNTGCGTGGGATGGCACNACCGACGGTGC
+
"+()&&!)("$$#'(*((&#)&#%"+"''$!#+$%+'$)($!&$#"+"!+!+#'''!((%+*!"%*'%*%&%**($&'!%*#$#$*$(%)"#(*$+)+'!%##"*"#(("))(*'*&(*%(+**#&#$%$("&"(%#)'&&
@r1278
AGNGTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATNAACGGACTGC
+
)*'&+)$'!'")#"$$#%##(("&##("(+&+(*!+&)%(')+'%%#%%$+&!#()&"(!*"+%%#*(*'*&(+#)$%++(''")*'&+)$)!!!&!%"#$$"+)'#+"#)*&+$!*#'+%!$$!!)$!%$#!%
@r1279
GGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTNGGGCAGGCCTTTTTCNATGTCGTCTGCCAGTTCTGCCGGTTTCTCTTCACGGGCGAGCTG
+
)?>'18&H"$<)?<!,:4GE3"=-&1?.,?,<H")/7DG/62E3DB+/(=?0FG(?3!$!%'*9-@&%==,*<B$F5*D$1)+(3@02)'AB?17#D#-3>'B@6&?C,;5C5<169,.)2B#
@r1280
NGNCGGANTTGNTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCG
+
"*&%(()!')$'$+**(+'(!%&%)*%#"&$*(&#('%$*'")#$($&%!+(!#"%&)$!*&!$+)*!"+)($$!%)$("')%*"##+*!&!"%
@r1281
TGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAANATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCA
+
.B?%/6;!<@)B54'06B:9$.8$5@9:C<9D#325%:1$'E8.'37G1(0@81HE6'?D4=$%<%5!)6>D@1008C8-C=/-&%H9"!A/=,/'1EE))$D>35GC5-'?-$:';E"C<DC5D7.*-H9(H27"8A"(*.:BF/
@r1282
GGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCNATTCAACCTGACGAGAGGCGTCACCTAAGCAGGCCCNTAGCTTCCTGTTTTNGTCTAAGNTGCGGTTGCGTTCCTGAATGGATACTAC
+
DC&#!?C-$'1&!,(3DG--/%9<<%23+E:F!7$.7,C>+9'=A4<'.>)#F:@)2-516@+1:EF:#,B&$+B*>%0>8*E/(4?G&H40#)>*+3H$"D#.></*(6#"@7=$<-@:2?D&9G8!*&7H=&G(=23&-/><CA7HBH)>*D!&,3D=.8H7D#+F,
@r1283
CACNGGCACTCACGGCTGTACCGGACAATGAGTNACTGTGGCTGCCCTGAGTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGNAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCAT
+
.?@=;(#<E"1:?#C:A4%9D0F77'(G(E.B(#-39>BF=)0%=F3068!%@5?!071*#0&0#4@3:,H-3CB,=AHF:-8&CF,#8>(=*&/"*+52$50>C>,.13$H8C<-67A;EA1:A($!(>6)!>9=&@F'727+3&@-;H9)?597E(15
@r1284
GGNTNNTNACTGNGNTANTGNNGNGGAAGCAACGCGGTTAATGGCCATTG
+
''!#"#'!(('"#*$#%$"&&*)#&+!"%*)#+$'+'))##%!")*'&!)
@r1285
TATCCNGNGNGNNNGTNCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTNTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCANATTGTGAGCATGAGCCCCCGTGTTATTCGTCGANTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACG
+
(&!*(#(%#!#!""))"+"#'$'"'!%&'#)(!"'%#%&#!#$+'&%$$+'#$#+($+&+)*&&##&!&)"$$)+'%&%&)!%+$&+(!(!+((+(#'((!*$*(')%$'%$*+#*!&)%)&!#"'*(%!$!""!&'$&+*)#"*$"*"*%+""!*"*#'&&"+)($$"+$"(&*$'+%&+$+''"+*$&$%"$)&"!#)$'#*++*")%##%!$"')(!$'#%%
@r1286
CGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGNCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCATGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCC
+
B:*6$"1?%)67)'7$<6G..8/:G25A(/F?,+,:'5=<4&;+/<+3H/!?>9=E!@%H')!85.6*(:&";;F+?"!$%3,>35%-F5*-62C:3/54CC>)<E3&HB$+6>D@<1&@,/%.6&>=8$'DHF;98.9273@(6D7.D@""D$G;D!3#;#"#@H!D$0494C;3.0/0&<F+9(<:G=53E*!5E6!,".'>8,/<6F:A"G()'#(&&1%=*,&D!3#9&EH.6&4G*:=*A@+''(.<@?4'EE!)@!(
@r1287
ACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATNGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACNGGCANATTA
+
-*!<D2D"%>E/.&/??<+6&3C="0.9*H3=%EC?*H:;:(&@021$(@)";'(?EB7-H(4B-$656(2D*/1F:A.$:.0HC<D)0(=4,8"D!!;$044H?'G6G(:-';B$G4?#C&C)F)!DH+/-"$G'H%1;5&)8&(6H:'@3--)*=AF.$
@r1288
TTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGNAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGG
+
C;!,&"0$65&'=1&0":3%06,518G(+G(0<5GH#(53"2"*9@.<<+9G'37(!F,%7(A16-%<";3#7><><*9D#!14*'1BH!6C)B7)5!/EF48:13/1'.=6;3C.H<#63'92)G0$GC.($!*@EF;49=E&6B1G82.+)@9)EG0701G/H*5)@G='6"3$9-'ED"#@*92B3D-'F=%B.#0@"FF/;%,82E'49'F5(0?:8,;1A5!#:'0A"375/$>>75
@r1289
GCCACTTCAGCACGAGATGCGCTGTCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCNTGCAGCTTCCTCGGCAAC
+
9;6%")38'-0*<C?78629,=1HB%(:,BA33!"H2>0%B?<4D6=4"%@4+>F9B>B(9E:$7=5"E<)H.@#6+:BC4<C*>%2/%#)1C)1B=E
@r1290
ACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCNTGCCAGTTCTGAATGGTACGGATACTCGCACCGAANATGTCAGCCAGCTGCTTTTTGTTG
+
8(4CG,18(/%7&?"H&3;8AH@.<*81C=%%:C/(:.#47H7"<C(3046H($8)*/2*A*'9"=!E&0=)H--4;@15>'2(86?+.,*':'.9!?;$
@r1291
TACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAA
+
708'4%8'+9278>$'?1&!<)>32/H:.DF+=-F1).*7*9'
@r1292
ATTCATTTTGTTCCCAGAGTCGCCGGGGCCTAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCACTCTTTACCGCCGGAGCCACCCTTGCAGC
+
D@><6#/F<CD$9*$F8&2$!:/.74G2(;EE57(1)E5?EDF%7:#C;F<0+0AB<<F$/BCE!+87)=@!(1"5!03E609F<73("/&7F'C0$>A0)5-H=7;&&99C7
@r1293
CTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAG
+
2,4?&3A2G"&='#5.FG#5.?#17"-GGE">92$*>FH?9B
@r1294
ATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGG
+
@:AB//*2=$<>6'==*BB?A'/#.E@0@$H,'D%&B1'"1<%!2%2C?')3;0G7)"!=7+8
@r1295
CNCGCTGACNNTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGNCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTCACCTTCGTC
+
""%(%$($)"!)#&&++''++#'(*!%*(+#(!)%*+!(&*+!#)!$%#$&&)(#*#"$((*)%)!)+!('&#(!(&&%*!*(&)')#&"%**)+!++!'(*)%&)(+!&&**!**()*'%&+"#'&
@r1296
CTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTA
+
>.F8<;0C67*2-%/A*$60D60&6+,6:GC7.FH$4.8F'G+!;!#40:'C,#+&D0+70)&;%9>C/7&DC?4@(@3:!#@-,1F%<%
@r1297
ANAAACNNNGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATCGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGNTANCGA
+
)$*'#'#""%'%)+#*%%+$&)#"+#!(#"*(!&$)*%(('#+*(*!&')'&&++"%""*))&'+#)*""%$#$$!&(&(!'%'#*"$"'$((!%!&+*)((&!(!"&()#+!!(+%(")(*&$"$*#*$"%(')'$''$"('+#'%!($'%!+")'$+&*'$((+&!$'#*(!%+$$('*"*!($
@r1298
GNGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAA
+
'#F>+?$8.4:"<*)":-9C8%5.20=#A%@6)C=)5-1"9H:F<%12!9B"%'=7#/>179/0=.9
@r1299
GGNGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGNGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGG
+
:<95HDD*CG-:(?8AE.H$F-D#+-@4D,8<+G)?=,@A84D("5$>#!F7*G+=6+@(+/!1C/F6G27E;3>/38E%#8)C+%39(+?0F@&,?%**%?G<%(8@.(C@?B$!G2$!B"29=G<=>+A;%+2!6?*!%@(66E.@#6B)C>53%8%!3>+-7D$6@?:F5BC-5&:8
@r1300
GGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCANNTTGATTTCGACTTCGTGNGGGAAGCTGCATGATGCGATGTTAT
+
+&#*&&))&$!(")'$+#(%"$+*+"##%*%+)$&!!()'%)$!%(#"*$$$!*"#&$##%%'*#'%*'!'&(*!+"(#")**
@r1301
CGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCA
+
6754F2,/.A"<@<>D($"H2G)98C5$G97?&118$-.$"A4&<G*>%4G8/4(4
@r1302
NGCNGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGNGGGCAGCTT
+
#"'%$+(%&()*&$('#"%*#$!#&%!&"'&)"'))''*#*!&&!$$"!*&')$$)+"#'%!)')+!'!+&%(#!+'(&%%#(&$!!%&(#$*''+')')!(&#$"++%!('(***#*#$!*%$
@r1303
ACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGGCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTT
+
&*6$=4@A:HD8(+)):11:%@F!6>$8@*DF=BF&4C)+H%)F:HH@7!(%"44<)H%15,(.%%+0H6/*6"7$*/)?=+7882D#G"A1'3-@?&!&!%53F"4G,-
@r1304
TNGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAAC
+
&"++#+&$''("!"%$&"##%&"''%"+)!'*!(*%$#&!%"*$
@r1305
CCTCAAGAGGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGNGTTAGTGAATGCTTTNGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAAT
+
H7-,/+4?E-@?6/=>E?5=H<>!F=:,G?"E&8>'9AH>@?<4&EE9"F6996232E;@$%:5?7%@%.5H+7C?)3!?.>4."(;HE95F2;D>81G<@=FG4,&B7.&?G,+&&1=G&25/-C605A-%)5-&,,?C76,"5D0";-/%.@)<*;D7218#7??76E0F(H&?@(.'A3$0;)2;>&-%E*0*4;2CCB3*+:+#H>#9@G/&A$/?
@r1306
AAGGAACCAGCACANAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTT
+
E9=7E1><%$)7-*#<@(>9<(?742!3/7H<5A#G.=4D0>;F5AD>H(9"%C:@:E58&/.>+5(B;,"$/3H53B"0C*3)G@!;F$#"@5=&,B2-G5GF*&(!')!8>67.,A?6$9!$@D6<A159;F8G?4<1
@r1307
TCACCTCTAAAATATATCAGCATCTAGCATGNAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCAGTTGCTCA
+
7)B>6"<*6;*3=;8<#+6;'0$)D:4?-)$?!>$,0(&&'2,F7=;F?!B:!6$49"1E5%B4*(C=;%:?79&3G2&GCB0D4?=:,C0&1%/!-(A+<#$:@DD
@r1308
ANGNNANNAGNATTNAGGANNTTGGANTAGAGTCCCTCATCCACNTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTNAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGNAGAGCCTCGTTGCGTTTGTTTGCGCGAACCATATGTA
+
)!&"$)!'*'#*#(!$$#"!'&()))"#("*+(#!*)%&!+&&#+%"!(!(#)(&)+$"!*%("%*(()#)+'!&#!!+&"*(#'&"##$*"#*%'+&+)+&*$"'&*')%$&)(()'$+%%+&$'(*$'"'(*+%'+++))$!#$))!&&+&&)'#%'*'&+#()*+(###)!
@r1309
AGGCAATGCATGACGACTGGGGATTTGACGCAGAGCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCA
+
B+(CC&#E@%D+.A'7:=123+*('%A160768=#=5*&A%1:2+:F@B%H:G6E69C-+@?0$HHH(&'./,;/78#!,.?"'**5=7=@%,249=>:9
@r1310
CTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACG
+
C,#9C(4#-&"3C5'8-92H?#65'7?2#':'"A*@+?3)$8>5*)7(B@G+/>?81<*4D+(%E+-H$A,=>=/E/'6G2;7/
@r1311
TCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATA
+
/*A8:H43<);8B.C0','B7E$5*F)%5<F2D%;?%"F87
@r1312
GTAATGCTGAGGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGA
+
:285.2'9#"$3:,-*&G5/E+A%'B;@7.*=37A-./%#-:A%($D9:BD!(=9#)AA9&*7$<*<'>7ABH>,H5"*@B28D3/)-C$8=4D(*/B.>?<C#C'<E
@r1313
NTANAAAGNAGNAGTATTGAACTTAACGGGGCANCGTATTGTAGT
+
"%)#')(!%$(%%%+%#!'%++#&+$'"*'$++$'"&+*"*$)$%
@r1314
ACCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGNGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGANGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCA
+
*'.#F%B<79)A(+B*.0+/H74-;1E5G1,86@#3E5G%8@=##?!3D?,C"?BA&;C$"();%)DE1*$&7?>*F5-&<;E*7B1,%+@$;'E+6DE&B'3$7#55B=A,C$9D")B7/)"&B#=;,F9%3&>#=E.B2#)::+6A7A0AF&2,2CB4:2@?F,"%<2+AAG+A2):&2,>)DC:,4H#'
@r1315
GTCNNGNCGCCNAGGCCTGTATCCGGATGCGGAGTCTTTTCCGTGGAAATCAAACGCGCACTACTGGCTGGT
+
(("($'#'$!*&+('!#**&#(#!!)%*'$!"&#)#"(+"!*'*))&#($**))(*$%(&$*#'#$!$($''
@r1316
GTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCTAAAAGNCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGT
+
'=;'(B3%..>>)H<A5*7;?21;27/1<G<!=$>#,95@@C$?>4",$GF<!,'@F(AA()1-F1:)53=;)"F%C>(>8-88B3>-A%-D)A.G4C#8D%:<A7HHE72/!H"76,>+1";E&$(@:@1DEGCH8@6"$(337<H7>:H,EFE'67(0F<>HD$H(43=>!**538D414&-#B#6=:F"FA8144D39F(9G!9H7*H@6C5&-B75-;;F!E>DG?)
@r1317
TCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGATTGTGATTAATTC
+
"2/*B"*'3"),+47.==%>D*?)0&6:(.-GH%?**,02/2%<H88!D"735.,.6(5E@#
@r1318
CNAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCAT
+
)+(%HB>F&E2!E#9)==GEB?+F/5:@;&!8>=-03@'76$6=E%+,61)=,02%B+5(%+>:1+/E'?$H/=B#;D6&/)0A#E.3;.5(1DG0)A%+C2;/+-A<"G+*??E&8F&(58#'+'2!2)=CC-&;:#<(>@%AF1!F";,H0H"747!8.;,9,HG8(1.+.9411G/$"1E9*63&/<BA"+A@!-&>!AF>/:H6)?1&&A*$2,G5+.(AF
@r1319
CCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGNATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATNCCATGACACAGACAGAATCAGCG
+
8F51$F,47!=B>?BB%5<"F0A$8B>B9148H21D+;%E$5&%!9$<+H18=:=*9"+$"G'):D-C><>H%FC;F8F-H7.!G0<C1A@>ED?9E!A>?"F0/=D?G39#"D27""+C;'A@$:6$2D30.H@(0&?&>6F((/,,#A+D7EE&8(,">F,")G=1&5'+,@GD).30D,9C7890-<C0/=<F76"H4:73-9(G2+2,F6B//E0<6;=33&$0;D;6'5'9)@"0,59:33##/7*'#6!.C3C-+(.3</D:*D$-.*DD6?=97A;8'%6?BC%4D+'G2C914;3$2%)C3&@@@-E?#+,/&5A*E75
@r1320
GCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATT
+
.%H+#'76.8>E=%%&H(7B:0C2F>(9=!A5@102:,/H%F!C
@r1321
TTANAGGANNCNGCNTNGCGCAGGTNTNTCACCGNTGTCTCCAGCTCNGAATTAGAGCCACGACGGNTATCCAGCNTCTCCTNGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCANACGNGNACTTGTCACGCTTGCTCCACTCCGTACCGCCGGACTGCGT
+
$&(#$'#%)'*"*)(%!""%)*)%&!($&+%!'$$$"!$")+'$('*((#$+&)$#$$*$%"!)$*!*%+")%*!%+*+!&#%&%$%)&%%!#!!&&+%'(*"(!$$'*!$+*%$$"%$!!#'++!"%%($*+&$'#)$'&'+(*$"+&"'*!!#"$"(!((!*%%$&"$'*&''*+*$&$"'$!*%#*(**"&%(%"&""+($*$$)#&%"(*%(**%)#&%(&*+*#)$'$#++&##
@r1322
GAACNGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCNGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCNGCTTGGTGTTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCNGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGA
+
0G2H=#298-.8%:.=?2*:>"-$40?=F2+70')0'88C3(D9E87397!:D<+H&7E56$"";G>C=$+79'3,8C":2(A)H<&?%&.*#?45-9:*1.4**-72?+0,1&"EH*$;E?(49@<B&;+#?1(%%>57)@8$1*)#3*F7H*%'4":<'3,8CB/EEC(754>6F@#3D46,;??62AB,5:.@AE((6>$(8G!701:75@)+.<B1A077?,G8+C2*7,A&H3:(*=5H688=G,C'E/"B80>>&":>7C@F%:,6A0;)G:@"?$(=4&6#'D73G#0D@./229-*@27;@G:;/&!1.F564=.0ED:14B)$(',=)3'&=!1-'$="DA+">A2'4""B;#%<1D;*4#=53$;9#F
@r1323
TTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGAC
+
7;7(CE82(D%!!==HE$987;6H":6A97?%=)!86@!,"
@r1324
CTGAANGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGNGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCAT
+
>E99F<1(57@81$"H'5>=1E;/A=+#).H?H8&!D<?//$=21)GFE/11.!/)9#/,;@!.7!H@)GH2F;C!G(,9&-&@<,6($53..&CF<+93A496629&:6'8<2$5"/5#!.8'E@*C5C("&-(@1G2.#9H))<:A*;$D+H<$#-8E7=:B-BD-);&$3)$$4%95507?#0"1=
@r1325
GACCAAGCNGTNTNNAACNGGCGTNTNCTGGCGNAGNCCTNNCN
+
#$#"""""#"$##"$$"#!#"!$"!$!!$$"#$!###"#$"!"$
@r1326
TTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACT
+
201*:B74.G(3@H<G'7F+G%)1/#53+E<>&C5*'F88D1%=#F4'519B%D#<@2F3E'.669@;9>F!=;&;A.2A<%@-&GAC#></5!"E67"'(G3,DA9<B?/#@*!A#B"H,6.8/9
@r1327
CACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAG
+
+6?A%AA7(FH39=1:4.B*/;94/0>??:&>)A.EE,B39
@r1328
GCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGNCTG
+
A75"19&D!9<28D?B<0938/.1B,;B3,)<ADAFF@D-55<@=4BH(@($22(=;?+$AA?2;E$B/G:#=<+@&>1B51<.)-C.6B<
@r1329
CAGCCAGCCGGTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCC
+
+&!#%%'!!"(""%)!+$)"*)$'%++$("%&**%$!'$+#)&$&'
@r1330
GCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACG
+
>,@,58:5<GBG&84;0%-<&&<$!-!89A#)@D+143HF5'@:"2*D<
@r1331
CGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTNACACTGGTGTGTTCAGCAAAT
+
)#3HBHA.BFEF#1G31;6-4H5+G<@1#<$)8)7;8&,1;2.2E&'1=9;?4=:70?78$"H=D$-(>"!(,B6.<C@F/%--21
@r1332
TNATGTGATGTACACAACCGCCCAACTGCTGGCGGCAAATTAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACT
+
&!39F34F1*"36'HDH0:&@.=H4-"%3):7ADGA1&1/6?/9D"820F=3/8<%.1,6(@9B$('/A93E@@8)&H):4($0-'1,-;*39$BC;#,!5&+G2,@H,7(E4<B3.7*$$/!7(CB/8%%&B6%'@5(>BB5F)4
@r1333
AAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATG
+
D$%/)EF0FA3"'@63/*/5A:D*81%-&E2.<:4'&/#0-4/D,6(F:F.G1
@r1334
CAATTNTTATCAGCTATGCGCCGACCACAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCAC
+
8177=)2."7-=5D<$/=..<64G15)EC6E'"D'3)!-H8#1+(,CB>65!4'0;G75FB@G?4/
@r1335
GTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTGTCATAC
+
>>&E4$%%B:>8:#,H,<4C4*?0+.#F%(##D28>--'(3&+EH?<#+F>
@r1336
TCAGCAACCCCGGTATCANTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGG
+
&+&)'"!!(!!)#(#%&'$*)+%'$$*#*''&(()%#$&&($!%!)*!'"&"+"$&(#'&!%'+#&&"((+"&+&('#!"&(+*$%!$*+!)(+!(#
@r1337
CTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCGGGCAAT
+
B;DC2&"/B=!@C/::(!B>E8A'FD+C!@6!,D!CF-4@?2<$D("0A!H6-*A$7,97%D/+
@r1338
AAATGTATATCGATACCGGCGNAGTGTTCTGCGGAAACCTAACATTGATTCAGGTANAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATNAGCGACTCACCACGGGCCACGGCTT
+
)%+&'+"!&%(+)+&%$'+"!#!%*$'#%"(+"+&"&%''"%!(#)+&)*!*+(*'+)!&"+$)"$!(*"('((#*'+"&%%+%(($#$*+"&#)%#$*"+!($#$*%$($%&+!#%%$%#)%+$#)'&&#'&'%%")$!'!$+*)
@r1339
AGTCATTATGACAAATACAGCAAAAATACTCTACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGNTGATGNTTACGCCAGACTATCAAATATNCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTGTAAAGTGCTGCTTGCC
+
/(G1H6A6=BC4D4E/%"9&@14.,+BF97!9"?1.B"$*A<1!7G=?E&/3B!EC4,@(18=+&/!;0-,$##)9.'C."@2C.#*=8!46$"4:>*$8+$02$<5:,:,)771?=+/?.2E=@;-;3<76,!>76A/8>85B:F@H.0.0!(D0''!6<:>$"A,13:*@
@r1340
CAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCTG
+
8<11,F=(+H;!59HH1'+48"=1*A$)6,5C,H'D(;H8%:B@E5!$&**(,0789.4??375?@"0AHAG;,.&%=H6!%$'=+7,(,8&2"1%'8273(@-H);*<H<"?:%-/,:%#$@7DD;@.85,8
@r1341
GTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATA
+
7/-+*!0%48A4:5%F5E8HD8#%.A6#3406;B&&#3+@6$'%0A@>!5"6'D
@r1342
ACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTG
+
)5;0'C*8B&7!="#;H9'<!)A0,955.'":-DGE(>5*,GC-A7D'?);&<H<<,9C%:F9&:++'2?.-1!!8/EFG=C=6
@r1343
CGTTTCTGACGTTTTCGCCGCACCGGCACTAGNGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGNTGCCGCTTCTGCGCCGGAGGACGCTTCGTGAGCTGACGA
+
0B98E=;303/'3D.%6%)F'D0!A6F<G#(A;E;>,E9F>E"CA2$0$;$73)41"?4/'&.6F'.<H,2C6.,8!%9CC&@$"+,-7B<!@E69/?;=+=5058A50158(D@FF4HG&/3D(*>7-!"0?C'=8G
@r1344
GCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACAATGTATAAATAACAGAATAAACACTGCNCTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGACGCNCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCG
+
<)8BC4<21=C4?"2"7>->?=C;""$(77>>4>0#82+A-?@+%&04FH41-:1"'4*G4A5%D25#+F9*@*)B.':0%-2:C?!*AB85:H0+3>F%$:>,H?(A$'6.9@3/;-+65677$%,28=$.A-41E5@E8DC3DB79'>&7)14(,A:B*C?0%%E+6&@C6';(&15F=DD78<B>42*.C)*.D-)&3,DHF(:43
@r1345
CAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTNTAGCGGAACGGCGCGCCATCATACGGCATCAC
+
?*#H:C!2(/8&)BF3#G>E)<%HB!?$;BE6>H9&62<36".;';8HFEB4%!<H9*9G4/C$-5<,%!?8<'-4/<4/DF78?=:B:.15>D6&E#)>H0#2!G&
@r1346
GNTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATG
+
*'/H,39E)AA66-B,;D%=)2%10<GFA;8><5H8*CH16"%B-
@r1347
GAAAGNGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGGCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTC
+
8'!,=B+BE,@&D:?(H?B(A:';0!0:!B84D'6GCG"1(B.''C"B2$A"3D=FC7/43.,H0>@,3<88G.+:D"=DE6B6-/A'E3A494+EG#."2E4A@1F+B.?!"B)2A?66E>!':B3-A6+;,)/-(377!6==E,'+<./)=F4CA>).8'79(#,H>$H$>2B(*2-3C*:EB!A+;A.&$:,*/
@r1348
NCGATACGTCGAAGTGACCAACTGCGGNATCGGTAGTAAGCGCCGCNTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCCATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGAT
+
-29#3<HF2&9H7/>2"-3E=$-CG6)7,5/$F57&7>2+@D1?@,G91A*.HA<AG-<<-+5'A5!H94:1'*HG=EBD@9$&68D$-+'F&E:D7?B>'!)!6"H36*!4<1EC$$9024)422>-$77/;F/=B(,0?<?(A&)111DD@>":"!$#6&"D0B9!C9%6;==.686"=,8HF9/%<>*/H."2'.B$!H,BE/=!B#@$B'=/<BF.+D04.&#A>+4)1568HC4C)&'CC=&@;B%GA)?$BGA@C7*#;7%16&0&&.B2+$G+&/#0#:2GG@
@r1349
NNNANNNCTNCTTCNGNNGCGAGNNNAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAAT
+
"$#$!&!((!"*))&%"#!&''#'"#*'$)*'+%'&($*"$"*##%#()"'++#%)%'))&#%(+&
@r1350
GACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCG
+
*'9E"D4"+.A:4@:7!F,,*5+@H4"3#=7GD$7&/$>9'>=)<86!."?"D.:&$$FDE@E#1,D"#/!+475%(@@B;"/$)':>)9;
@r1351
TGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGNGCCTCG
+
5F#1HDGC@C01C0:C=$@D)&#G+)DF7-9?!CA>9"(9%'C##222<3/<'GC=2/H;D7=(=D9+=C"8G+)!8C92281<&E):>99!.
@r1352
GACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGACCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCG
+
/D::?.=":0/GG18!B!'@2;.,'A*5#05E,A#-%(D#>'>"H84G>#B0'B54:G/7?7>3/B/>/"18.%@C<D2&9#E'FE@3@8BG@DH$E2/1<&(=.<%;7*;H+6HA+H?<86%;AD'BH8'808<A"&4C)-0B@4556;C&.;3/
@r1353
AATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACNGCCTTCAGAGCAGCCNGACCTATCTGCCC
+
(07/1HH=-<22#75"8%)E5<D$3.2#&!-9C3AE50?2:E+1=!F9B8<&4&38G',E2=&@?5>'0
@r1354
CACCATTTCTATGAGTTNCCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATT
+
++%($"+#"$(*($&$%%$)#)+$&!)**$!&*%)&!&%#!*!#%"'")+("**(%'$%%#*$)%'*(&
@r1355
ATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTG
+
74!G83E6'A+C*.5,#FD%B$G.H$B?%==A&'28#-?B-!9'?FG6!0."C0"=76E%&=*;C:46&7+&"2+D,?/=528.>+@%<
@r1356
CTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGAT
+
?=E76/#1(F%@6C=B2%A?266*!->/.F<0AB,'$05C)3@'6#!!4("0E4!:'(/)9H<%1?9G"1?)C"?-"@HF70&3B%68D:<;@GG
@r1357
ACNTATNTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCT
+
'+++))&+)"#%+%+&+"#*++&**$('$$"%!(**$+#!!)%'*"+!(%*
@r1358
GNAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTNTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAA
+
'!G?&H*62C*D,?/')?$B--0)2E%8D9:0"&#+1-,%(:'(8*/(8=5G>>HC5<+F8#E%16H0)5G1(G'-9E90BA$14)>96FA:1H>@D"F6#-99A,#&27E1%F.*(,:+70(H(&?3,A#?/>%46630:G<=A4@C#)@#$>&C@;9*:3FB;"(?75*#
@r1359
GGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACGAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGTCATAAACACCCAGCAGCA
+
(&'D$9<(<!B0@$E:365$#4=:)05>)<%2!6()-@C%@D3B%:/;8!2&+0.@:%FH5G<E6F!&:E#%"1D78B$@BC8A(>D#93(E('1+9!,!55!"<<>91
@r1360
NTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCC
+
""36>./G-@9+02);$;C5A)/G.%<8C+56"C!%."29=3F75G,3H#B4'.,?#,F%3($%4-83>2C"36&
@r1361
GAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACC
+
H<0.B/"84?"8*4,FH=0H)+4G<B=>(<*6!D##!F=AF=
@r1362
TGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTT
+
B:*5+8+$>$?6>G806<!4HBA@*25)?6-$7:-'/204?+G
@r1363
ATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAG
+
C$3#B-;=E>G4C(4D<@0A>).!<>,!(>+4+.(34>43G@0E);=*$1>A;2D$G(.1(*-=$4G7'&/'9)@"=?B?>.6<;
@r1364
CTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTNTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGA
+
D+"C9=6=4$1?B4@5/:(-0"68AG<6#,?1>,'5-H;=8=:9!9"+:1/=(%%")B6H>0F%HF6E634/381%?>3E@,)F68>"!;1DG:A=,$;
@r1365
GTCAGGNTGTNCCNGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAANATGCGGGAGCTTACGCAGCTCTGCTGTCACTCTTCTCC
+
'*)((%!%'$%(#"+!'''!$$%)$#'&)$+$"&)+&!'*((*&*!"#$*)$%"*"$%!%!($#'&)"!(#("+###+#()"&!!'+$#$%"*"+"(')+(&+*%(*)*)'()(((!$"%"+%!'"++%')'#!%)%$("&%(#$'*(+!"'+)+!$&!(#)))(&
@r1366
GNTTGCTGGCATCCTNGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACNACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCNTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCNTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAG
+
%+)%!%$)%%)!$&#!(#$"%'%#'$#*#*(!)#))$*)%"#%*)++($%("&$)+)")++'+"!)$%)%!+!!'&)'!()(%'"!*$&%""'&#*'$#&%#%*)$*&(*('*$$)+'%*$*"#()!''&"(!&!$+(+#"+#(!)&#*+&%("&"+"#&%)+*''+%($)*$#"'&$$'&!)$$#)%$'&+%)#'!()'%&**#&())!#$(%"$)#&('!$%!%+%"##)**)!+#'*($"+$&(&$&&++#!+%"$#$!"($""!$*&
@r1367
GACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGC
+
47>*%DF8)'$?&&<-(F35##",0)*:"H1B5;3#<32#)49@9,>53B'"-H/:5>9#6D022E
@r1368
GCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCA
+
0=7?!@880?4:&$&7B9E@D0:&""'/5#6#&)7<A>-F&<4-*D-2%
@r1369
CNTATTCTCTCGCTGAATCGCAAACCGAAATCACGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCA
+
"#(+#!'(*)!"%!"$"'"%*$%#"*#%"'"(+'!+#)'&(%%(+'!*#($((((("%)(%)'!%%)!&!!$)(+#+(*!*'+!'''%
@r1370
ATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCNAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAATTTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTANGTTAAACAT
+
C?9F:C%F"-,HCC/&"%)$&"'.E@=8DE:F%-';:<<H!H=3+:21G)8.8=8,5%B!61F,%#$1B08!*,G;+3%/10D=G.7":<+;*!>#&H<1,"<"FEAE!#867FH3#2#+.0$33B=,(8!:/,,*EB*;HB&A<6:!CCB#,:C";@058"*0/=2<++;6286A.*.0"=<2?"!;H>G3HCB21B1.,37C*/;-?+*:6"#/0&270FDF*13H0068=22,B/B&FDC&D*7;#--F6B%";9=&**2-!)*'>!057C&99*>9<5G6"%D=!E1+'742""$2"FA,@)#8.)7+"#><-)7A!-G>)=8EA+.@10
@r1371
GGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCAC
+
=57*B>2@!&1H=*68$,-!>")E$28:)?E@C%GF.57<#(&461G,94@ADF==2(#&:$,12;=1>G>=5E>32:EB%67:;:>9H=.+-,,
@r1372
NCAGNCGGCNGGNNAGGNGAAATTATCATCTNCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGNGGCAATACAGCGGTATCTGGGACGGATCGTTTAAA
+
!''')%%**$(*)%#(#'''((!)%%'"$&'"$(+")+#)"%$**!##'#!#*+$""&)&'#)'&+*%'$%#))*#%('$"!&+$!+(%)&)*#*!(&#$'"$(&"+'!'#&*
@r1373
TCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAANGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGCTTTCAGCTATCGTCACATTACTGAGAGTCCC
+
)(#+$+'$!(&)+*+!!(&#$"$*+("("))!"#%%%(!*##'"%!($($&%!"&&*)'+%"#!$$%!!($'%+'!)(&%$'(()"'%+)"+"+'()&%*#"!&(%*"!!*$"!)%+'!*(!&*)&'!
@r1374
TCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATG
+
&<CC=48-=$BA;B@#(@1=HHB97G(3#?8?@+F!7>$1F?/&%8)>%)*7/*AHG/392"45FBC%
@r1375
CGGTACATGGCGAAGCCCTTCTGCGCCTACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTG
+
?;=3-//C!3#3H'FA0A)2=964B/,)7A(F&91H22)@5-8&1"3!%"*BF8"@!'?)->5"@6F%7((>5$1>%759;@4?.>61"C1(B;)66EA;<.?$60D$:A?*D&#(,!6"30>B5'C*-6?'8+:?3F*?A>9B$"%!(*42B9$&%./"('F.;
@r1376
GNCTTTCNCTTCTGCAGTCAGCTGCTGCGCTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCATACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAAT
+
"$*"'%(%'+&%+)+*+''#*)!!!!*&'"+!&*'*($%)(+'())"%##$)+!#*"+"$"+'''$"$!%'*'*'%"+))"!(&$#$!'$&&!%#&&'$*&*'%'*'''#!'$!'+&*!&($)!#$"'(%*"%+"%'&#'"*$+&$$&"*#!#)($+%($$!'*'%%*%#&**)!*+*$++&%"+*!&)*+)"$#&"+)!('()"%)$$"+&*&'"'+&)*))!)#(&"$%(&
@r1377
TTTTTTGCGTTGATTTTTTAANGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATTGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACNGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTCATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAG
+
H%(05?6>H(<9($73%DG";4*:C;.=&97+"DC:$=?=$$1-F$;7G)7@79A%0F75?0426+=35:=*6>C!%,*D@9*"(>&9"DD-74GH#@,+?D&3:C.*6$3!GDF5;CG235,0%:3<+/(,9/-:F=!'8#<8@&:,4&":,-A7(),?H*B3!D1F7AB3-A&8*#989D,?6'*<?!<<H8#,05"656'3,CG;G>D%>-%'2.&72/A0/A@,F-''52"H@#?5#=H>$6:%$6DB*%#71/5;H%#FH*>-",5+<:8H$(&+)D9+9
@r1378
TNTGAGGGNAGTGNAAATTCCCCAAATTCGATGAAGATTCTTGCTCAATTGTTATCA
+
?:68(/!#!&D0$<)96)3*;'D*72%!<."&6=,FA+78F!(,;,>0=%<FC17,(
@r1379
AAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATA
+
>0HG;'1D)HH5502E%<6?%=/@2GBFA@B,E$8E'5&)80
@r1380
GTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCNGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTGCCCTTCAATATCTGTT
+
5/<,+D&!B,D$C+"<'"%7>5)6-4353H!"1CCBC;+5EB1-3'"F@A-ACA+H!;0D0#2:'@@2.(/C87&(B$#'$:)9>@"1-?E>)0>8(7B1<<(6H8$H*5+@3*#$"303A0;G-A3B>-)>!/!-BD@DC:?D8@7F18"4-:%*>5<6%A/34;1)0C"3@@D!&8/8&$E'0&+2.4':G3F+&4-2A35F+1C-
@r1381
GGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGA
+
<!+0'!#CG5#60>:?+("(<;?)&9(!E97!2$A>&(""G8
@r1382
TCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCNCCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAAGGGTGCAGTT
+
8$5D"=>#ED'1*"8?6C)3B5E>?!=DE(>H9/,/>:5-E3:7#E:(,?1"?H3/,,*D7A?@,%E39E!1)#D32+1*$*C42,E?BH$%841AH+@/'1=03?#AG1/H0$68($4?D;#(,.H6%*&?!&F$;>">(D99$)@5;"G#;(0H43(@H0/C@B2).94'C<1"!8E)?".1G
@r1383
TGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAGGGTGAT
+
+89@0BF>D"3C2!)@0,4$D!D<'76*05-=F$65$.=B:B/2<-E,3#=1
@r1384
ATCCCACTGAGCNGACGTGANCGTTCCGCACGAGATACATGGTAAGTCGCGGTC
+
<A844>B?*>@7;$89F(E@9+?!&$42CG9#:9.$353A-#?D*H4':"<:3$
@r1385
NCGAGGAAGNTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGAT
+
&A!17**@A,A2(5?'GCB<"@!>8##1>.+-*$/@3(*/2,)#,@B<&-
@r1386
GACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGNCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACC
+
%2)>$--!8E?G<G+G+F#(.A16*@+26"8B5!<(HF;3CF4@2EC=4.471'D.1!AH7)!$69EH8FB3D7"63@*%A$!G1D$<G,37&&+;-@+?:899/!?GB*D&-)2E.<%0C*!:6:"H%>'&4*0<86"&B>)(H>&@(F%</H:3D><-?>H<
@r1387
TGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGC
+
(.DA563)@C*$=G;(8';.@3)D')A0%;6EE00.;1&':
@r1388
CAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAG
+
7!@>:F-!/HF,/>HBECA"$!?H3'F:2$=4F3<G9D7*B/<E51;'=%"*)!E9;"24037:'*%#&"C8?6G
@r1389
AAAAAAGCTGCGCGAGAAACGTAAAATGATATAAATANCAATATATTAAATTA
+
))&*)#%'#'&"+!&$&$##)+'(&"))(&"++!)"(&*$#$**!(+*$"%(#
@r1390
TTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGANGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGC
+
9<1FH!#)8/8--B2/B;E'7*&(=1@G&31%=1A.D;62/D<'.!>6++(3+66AA8@=!0*$13<(F<)20@,?>652F'H,C-6'<?1F3$6(BD30&>:$5:"4B/6;:754B7@9C&1:C&:"@6974;2*4%E/*0*BA:$6/2=C8AH
@r1391
GGGNGCTGGGNAACANTGGCCTTACAGCGNNCCATCATGAATGCGATGGGCAGCGACTACATCNGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTNTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGCTGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTG
+
&&'&('*'')(*&%$"))!(*%%"!'%$*$!(%*)+&("(''!*'#*&"%)#)#$"&+"(#'&+*('*&*+"#$(*$!'*&+('(%$$#+($&&*'%&"(*%(!)(*((*+"&"*$"%*"!*+!%)%!$%&*!(!#%")(##(#$%%()())"%)(##%#$++%%'(&'!!%$$%!(*+#$"%"**&&'+%(%$#('&&$&&%(**'%!!)#)"+#'))#)!(!+)$**
@r1392
CGAAACNCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCAC
+
#'(('""(++'+)#$+&'##%+!!"%!&$*)#!")+((#+!$)")*('#%#%+((%(+(%*!"$&'$$%
@r1393
AATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCNGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTTCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGANCGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGAC
+
FC,6#E>17/::-@(,6E5.$9(4F;+E<FCAGGAA0#<@FE4=G(>+63*1(B0#&"'<00(+>'@::"+;$%=,0HB!E*'!.68:4!)F!3&HH98%C92872/"15EF/)8#5$#.&A!#(?2:80"?'*;'-H5#C,.%9D"-C9!B+2-BH<CBDF-47'@("=B!C&@;48&?./=<##>A87BCGD!8<6<&@:!?%2+&:+>@C(::!:/#3'#+822,4&B6(/F/&")/<+><5H<<*G1G:+15$$&&@H18?2D:734$&6,>:/*F%#)H/1?8G"?*;<6@)+2=,6+.<H3G2"91FF!H>D..0FC'<<C773/5F:<7$"2#2?)4%=)*#@C)
@r1394
TATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAA
+
#.=%3>5F?D+=D""5&&E(1BG-B@3C1)((%E-D=>?>>!&%D:9"C7/F%H
@r1395
CAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCTGTTAAGGTGGTAATGGATGAAACGAACAGAAANGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTT
+
3FA5>-#3$,7=35@G-84)DDA#8&68H0(7+9HEE6.>F4FFF(0"C9!$E1$6>%=6A@;0<%&?+>'G#5D#)4C96;%&)G$H>F7+0CD;E0?(;31;(B1,/C45<HD)9D".*B4"E,/$:A!)0=8#(934./0'/D-F?'+@&376#9$2/2.61$F17F=38C
@r1396
GGTATCGTTTGGAGGCAGGGAAGAACTTGGGTGAAGTCATTACTCAAAGAAACACTTTCGTAAAAGTTATAAGGANATATAGTTCAACCGCAACGTTTCAGAAACTACAGTCAGAATTTATTGAACCAAATCTGAAACCTATT
+
5+!=*G'CG"G:"?=8;.D*7!2=FD5)F(B67/=(8GDGD3/;%,:67&!F8<9GC&*G6-1A-BA4E/;2F58#1.B>-+@G!(=$*6".A.+")GE8)F!.28"&&D""6.:0F01!%2E44A51<A7"G8-#/@251HE
@r1397
GCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTC
+
BH>:"1H(=!2@,&E1>825%E7.)?@#.7H97/)6H@".-G%8(8":C#E7E%*50?/#A)07&20<<(*&369'35ADA:'H$&&9)7+G069D3G5>G%*H$E)8'#,@@5!:H':''*=0C7&""*E%?=&67'D&>5<?D552A(-02*<!$9=5C;7HA+.;B/F;
@r1398
GTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCA
+
AEF<2&'?6!G"9?AB$?$%9D@+:H:DD-C?0/308<&DB:*#G5&47
@r1399
TCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTA
+
8+316%E'D!2$>*BA6"1C(<=?/C.+!@<"%C0)&38E,@'G-C)G,(D"#'2,2";3;F
@r1400
NTTANNGAAGNNNGTNNNCAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTT
+
$$#'($"'&)$&&"*#!!$+'$!%*$%')*+#+'!'#''"%%*++#++"%'"#&&#!$)$#&(%!&
@r1401
ANNATGNGNCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGA
+
(!%'%)!)*(&+)!$%&#%)&+#!)"!#$&'$$&%($(("'(+*$)&&+"!&+
@r1402
GNCCTGANGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAAT
+
*$&"*#'$&+('!+'&+)&&'%!*+("&*"+'"+(()$((&&
@r1403
TTNAGTACCCTACGCCTAATGTCATCGANGTTTTTATCCGAAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTANCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTNCTG
+
:$*H2+BA+@G3,F+*1:8)FC:C:E?))&2@F=B=,*;<4F1@1(C"B<:20G-+A'/%+7?@3D59-2F9C=)4#1!#><-F7H#:4*)3?2"F!H-#C8.6"3C0!5G(D$
@r1404
TGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATGTGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAAC
+
;9.8(+)D!G/.,!-)!F8CB*<6,,1"CC?62$F+%0C,64<$7?BD9+,&B3%*7G#:*$#)C:#<*<).*6)$:5*%.D92$,G68F!6((#-6D%+?2&(:0@D"8;5@"<,0-1+;";E"2>$BH+<$:B%F@@4$F)B*5-0)E($6;$&?#=<DE(%'/&)G!5-+2F0EF9E"5F<A%<D(1B,!6(:(0/(0=91<",F-92F=#F;4"*3>)<"+:2&H+<8.
@r1405
NAATNGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTANGNACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAA
+
'"(*+(%%$((''#"&''#'!!$#+"%*'$"&+"!$$$!+$&+""*(+#$*&*&"!)###!"%++"*))#'!$")%#%!#%$*+*'!'(%)*
@r1406
CCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGNCCG
+
9(<.&')=?F*?''*E.8$9&?7!$";78=#?>8G258/<B@.,2DG/8##2-1"/A*'4=("=#?H4!4G!0;+A)/):-&D5GB=08E++D.$4.7!D0)"G/8F7D%/02D*;/29++!8$H"2%5.73?7%
@r1407
NAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGA
+
.1.)7A*&E!4!(2$4#H??:94?*B7#:F(=A<*2+.&&=.=!>:/87.A';4;F+=5
@r1408
GCAGTAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCT
+
=;>2B,4&8@3D=837)%;0(4)<A?7?H0&1,3%H9%D8?
@r1409
NGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGA
+
!=12#B#-"6E,)B'C/(B#<)0<F=4H*;4"7C<:>E<23*==:812&<6"2?-/!4G2@0@6?8A*3%
@r1410
AANTGGATATAGTCATTNGGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACCTTAGCNTGCGGGCAAAAGATGAGGC
+
'!#'(*"&*%"%!#$%)+(!$++$"**)()')*##$*)!!")!"*"$"!+#&#%)++%$"$'*%+#&**+*'%*((*)++*'*&!!((")'%$%&+)#$(&**&)"*%'$'"$&()%(
@r1411
TTNTGTNNNCAAGGTGCNCTTTGGTGATGGCTATTCTCAGCGAGCG
+
%$"((*$)!'$(&)(%$%)#+(+(&$)**!$!$!!!$&!*%*+"!'
@r1412
GCTCGTCNACTCTTCACGATTATCGACTCAATGCTCTTACCTGT
+
)('($')"&$+(!#+()#&%#(%$*#)%)'+##")'$*%+$+''
@r1413
ATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACANTGTATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAA
+
&@=)DB.703%?H=D$,G:02G&(?=)B@4,E+31'#8/,0377E<+11$%E,$H6)"+!809.*2E6;2E7+1/4(A/'#E3A1+A=35$/(.#6*?0F-*#$'B?!D&%A;1>-+8.F5'?D+8(*:CCHH"&$@1CH27234".;A=!+")"C)35GD"%;
@r1414
ACTNTCGCNGTTGTGGAGNACNCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTAT
+
!($$&$#'$&&!"'%)%'!(!(&$$+*&#%%!$#"%#+%$(%)%'!$%%!"'$#*%)&*(+"%$("")*%"+%&!#"#"'!()&&%#)(*%)(!"((
@r1415
CGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGNCGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTA
+
4+0675"G%12E/0?1H7/D/"<0H(,+&(&/:B'?*&A/&#:E&"12F3/!=2E2);)<3?@*5,8@GBEB%*D:/!+8:6=>%?#F/F@9391!E*&69><5"'2%:-=3+5#:"$@965H@B:E,DB/2H(D;C%.C(E4(:F@5-F0$3@B*H<$8B#74=8:-'5?69F!+DC.....+*6H+2"4=
@r1416
GGTCGTGGCTNTAATTCCGAGCTGGGGACAGCGGTGAAAGACCTGGGCAAAGCGGTNTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCAGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACN
+
%?B%)7F4%A*.'/#%="E9=0'##??-96:H$+3F4:+@,1@4-'.D2$;<&*G%>+D)!8"E#"0+16$*%"D>H1/=$3<9(D#';*.H#B"%1";/?H!+5!.D<,3%!D'''/1&69'")<1@3;!?0#1=&!81:09?.F2>1*D
@r1417
GCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATNTAAGCCT
+
A'$&8(@(*E"&@'6))=?97CB.(3B<G=5/<!F"B4(F4H*7H?)8?DBF;',7C.?(/9G&
@r1418
NAANCGTTCATTCATATATGCATCCTTGTTTTCCAACTNTATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCG
+
$''#++#"&)'!*&")"%*#&')&!#%#'$'"*%""(*#%(%"*&!''*%*!#$)*$!&+##*%"!#))#(($$**&!&
@r1419
GTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTA
+
H,51'73C&FD)96+F4C.599?CG)119&2E>45@E,B@?B=29.")8AH))!;.(+A'3$#$("5E%CA4)%2:,B:'@)*)?,+BD?.%%"
@r1420
TCTCCTCAGCCAGCCGCTNTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATA
+
D="9?FD*,=77(!8$?1&2(,#/6?%.+%4016%(=G.E-3@>/@52#01+6>.><!/+
@r1421
GNTCANCCCCATCANTCCAGTCGAACTCACACACAACACCATATGCACNTTTNAGTCGCTTGAAATTGCTATAAGCAGANCATGTTGCGCCAGCATGATNAATACAGCATTTAATACAGAG
+
'$&(*!"!+*'()#$"#!!!+)('+%)#*#(())'+(&!!"'(""%%#&"*&$$&%%%&)%'"$!+#!)'$'%*&(**"'((&&*&##()&$"+()%&"')**&%!)'$)*'"(&%"!$&"
@r1422
TGGATACGATTGGATTCGACAACAAAAAANACCTGCTTATCTCGGTGGGCGATTTGGTTNATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTNCGTGGAAACCATGAGCAAATGATGATTG
+
'G#<G"E>@/C9##-G8F-9B&*.:18:@$C:;<B<54;/@?/#497(/0'2H7<F!DH$;&C46'"2)H=2D1;<.+$2>B:')@=B8A>);!:-74DGB4D*D2%&)H<H2CGF;)@.8.E+";3"$44-.?*GA<1>+?@<G0!9%4
@r1423
TATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATG
+
:+CG($1A$'H"'226,.%":9'0(>.1G2=0%,<$,0;*2%"HF2H7)<CB0(-?8;
@r1424
NCCTCGCNTTAAGCACCTGTCGTTTCCTTTCTTTTCANAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGN
+
"()'+""!*!+#(**#%&+%&%)(!+"%*%(%%'*(##%&'%!%%"+)##*))$$+(!"))%!&((&**"()$*"()*'(*!!++#)()#***(&"'**)"*$%$&"&'$"#+$!+"$#+"(###)(!!
@r1425
TCGATGCACGCAATGGTGTAGCAATAATTGCAACTNATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCT
+
389D'C0=9#)HE:58.4%25,"EA;&.$E-E)GCH%+D0A!&=*F@7C.?23D117D;4>*,$4/D7D#H1)7$D>H"C$!G.C?/@3EB@=
@r1426
TGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGA
+
B4A9H(""G+2!$'2EA..>%E+:F*;B5/>C18.:H/3.AD<->=D7D@@*6A8C-:=ADF=8AA4D&>*>2"'9D$1%F@,)29=2&(#!A*'*2&?'*/F,??'=$@/
@r1427
NCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATT
+
!'+&++*!"*#%&!$+%('#+'%(*!(%&*'!*!#$)+"!*&'%'"&(#$+$$("("$#(+*#+##!&$$*&
@r1428
AGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATG
+
(07<*F$E!<3=+2.++,!>HG**=F7E,:7:8@17@$.DF7B(190H3%:&F.75+&6'7379*5'D!$&4+>-F-1$""EA&CA:"?/B2&$F-@A$HHE6F6:FF5=5HD3@,$33F.
@r1429
TTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTNCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCT
+
A,=$#1%(0!-*?1(H,3/;&+%C855A%3C(BB;H1#,?9,:46"$E!@FA89$$<294&<81)D6%F-$)<4:6@F(>F7'C=!&+8&*5(0/4%0@<G-/44%:E&5'*@>;'B"
@r1430
NATTAANAGNTTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAGTTCCTGAAGATATTAAAG
+
$#)("&#'(!+%)+'""*!&&"&&)"*%+(')+*#(&%#))')$%**!+''!#$%!+"*+*&**!%()!()'"+)#+$+#
@r1431
GGTATCCCCGCCCGACAACGACGGCAATCTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCA
+
1(9@&G(!2(#*#G:@2%C8(C0('2C;5E4D.<8G.22"8B,C*A/"5''4:1&!8=).'8:"'98192
@r1432
TTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCNACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTNTACATAACGAAAAACGCCTCGAGTGAAGCGTTANTGGTATGCGGTAAAACCGCACTCAGGCGGCCNTGATAGTCATATCATCTGA
+
$%%*$$!+"''"'$)))$!&%!*'$"&&"!"&&'!*!"))")$'')*)"!#$)(+($$&$$##%)%%"$(!&(++*$&#&%)'(""%#+*$%(&!(%+%+#&+!'$'+*(*&*+"!+&%%%*!)'&)%*$+$&&++**%(+%+(&%(+&$+)*&#*"$+&)!
@r1433
GGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTNCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGNACGTTTTGCCGAATTTTTTGCAAGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACACC
+
,)+8D,'1+",6EDHF/)#'<;./H3>6#!%@$2B+H'7E<8D3#2$AA"0'";):#=&+*7/G9'1.#=&94/H,,H.?=4@!=4#B58%?'C>+C@1C7*HEA:%C55.1%?&:>G!:2G<7!"1:.8"10$<=;?.8;=9"4?C&C+)1(D5&0-%,)&+(/F?13!2G:?>(;8);"'D=;%0,*4(-+-!G!*7591?5+B*9FC.!8.?8%.A14#G4%860%**+'?AB4?2B1;$(-;G+%34?:!?)H*=D4$?H8F8"C/(!70F5&>/?G5F8(43#":>#<296<";BD&"7$.
@r1434
ATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCGG
+
D><B>&C*FG5'.A=E*79:C)>!*7F0;%-C+G3!3#1GB<4
@r1435
TGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAGCCAGAGCGCAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATAAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGNTGCAACGG
+
F+<BH/A)/1?&(?!FF+".D5B>$A8/B14=F8#8#*4&:C*-'7.&G3*15>.1<8A3"!-97"-%&3E+9;>-FA".=C3B-+>(G.60*A5%38D3F/3..'G7&+9$A@%?$!8F3#,2!!G6.3B*,%744E4!>#)D*)%/AE3H$664!<:8H$,F5D@,#&<'H%??C4;=%!%ED"E5540153/AF0B!*6F1>=G=+E2
@r1436
ACACCACGCTCGGTGAGACGTGGGANGCGAAAATTGGCGAACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATC
+
C$0,.<+*/9G@C8/*<*7%7?@G3+GA@A0%FF&)91.>>2!H19?74F1.!1<FA(8F.8+*'&36(2DF46*>?G*8;'(A#=C/=0?H8A/D%$/50D-30H>51E+/?/H)&4<
@r1437
CTCATAGGAGATATGGTAGAGCCGCAGACACGTCNTATGCAGGAANGTGCTNCGGCTGGNTGGTTAACTTCAGATAGTGCGGGTGTTGAATGATTTCCAGTTGCT
+
?)7/E)4'8:3B6>H%GE=6)H9/3C<"!A?C3H9=<:%6((F&(#>-1@)>&"C"<E/>:G">A'F"?<4)1,H3053)(A-="H1%)!9$(02"?%,CH<)DD
@r1438
TTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAA
+
%1*%5(D*9(?.F#63783<(F><.&9(@31CA(5%)A?FCG!(3#@22%8#=-9C&H5
@r1439
CTGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAG
+
C*?/8>"(4!))EC7!BE?G94C'/(A;<$.>1#%CA>?""%&=%
@r1440
TCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGA
+
"C%!,"CE:3=><>8G;76'/?E5(4!;#C7)&EA5&3A?A>:,=F"6($0.2G'*G#/?2!()&:*.-*!>E@=/@(!=/")
@r1441
AGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTNATATGGACAAGCTCATCTGCG
+
;D%#2?"?+H=?.>4*:-%:1"(A-5AH?H$G:=+9/E=641C+0:B!H<5D?066"7A'.3%#/E<>.->(:'7C#/,G.G/3<4!H7?-4.>EB7#$CBG"07D21D1"7$<
@r1442
TTTCNAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTNNCGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCCTTCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTNTGAATTTCATCACGGNCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCG
+
$7!&8BF/7D*-<1".@B*%7"(5/&'9!:@1DB!<B2#++$>1/=)6/%2&B@3D993,66#7F6,278:%+DD>8E$G'$;;#3D6A4+7&)7$;,:'$A&B<?<:,9+?1E,@=4'"3"H/-'?*(+=::2?8>*="A7G5*0."1;%4%-9:/>:HFG"9<"8--;,15;<<:;!C#/-)/B;#/,6-?4E19",,1>/E%02$@CEH@9")9H(#20$8D#,;4+"F-':*'G3BEB:"$*/2%H*'(!D87<.3.8(:??4:+1B,:=4#H71%!7,.%8G$6)$>:G$8C%*4'#'4?=,$(GD>8+,52"G?G
@r1443
CCANTNNTNANGNNCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCTCCACAACCTGACCACNGTCCCCTTCGTCTGCCGTGCTGA
+
%"#"&&"%()#)%"+!&"()+%!*+((*$!'!!&)'*$(#$"%!%)"%*+($&&+!'!($!%!&&$(%(#(+"!%(*(($+%*(+"#$#%"%)")))*(#('*&&&('!*)*$&'+&
@r1444
ACAAGTTGCCAGGAGGATCTGGAACTTATCAGTAANCAGAG
+
%F.7<<D0''B206%)!+!7-263!45@;<D=D*13/B+-'
@r1445
TGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGNACAG
+
/(!8@2)*F@'('%.D3.A,.#$*2E%45'<A%/:FDF73.)6H23@6?+#;
@r1446
NTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGGAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGAN
+
"&1=!D1%:;9'?5H-$)'#@6:2..0!@DDC=:F5>:1:/+8#<53<7#<56@DB6(A6*>C46A"8=@A#H!<@-!AB:;6HHH6"1AG?08C$GG3.6EC2GE(6)0F-47G><&8:38.13&,-81<,?D7"
@r1447
CCTGNNAGNAAGAATGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCC
+
)&&"')&#"&')#"&+!*%&"+*%)))'%!#(()!!%'%*()(+*"%#((#(%#
@r1448
GGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATNAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGG
+
/6!E4:/E:$>?@=(>>"1E$'12/#,"$18?;1E'9FH59"?7D0,($H5<"5'.G)G0*3#G(4:-+A9A:@4H/+BG!;.D*C@),(D?&&9#"F7!;E#,(4E=FC1$@B!H6G(5.4"H</@*FE:6B+*:0=
@r1449
TGGGTAACCGNCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGAGAAAAACCGTTACCCCATGGATGTGGTGAAAAT
+
=-3HCA-(597H#&5E,B>C5#AEG:%/9#&:D3&9625E@5<C4/F)%/2G*G<,+$4;%7&/+F=+%%=#+(FBG*21,,?4@A>7>*2;DD4B%(384?92<E"%A$%G
@r1450
GGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCG
+
72&"),.'1F=!HH%6C"0/D%((HEA47B29?6H,9GB(!,G2!8+@+/-A
@r1451
NNTGGNTATCCGGATCGCTGTAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATNACGAAAATAATGGGTACTGTAAAAGCGG
+
%#&)#""+"*((+(%*"+&()*#!+"$!")%*&'#!+*&!%#$%)$+*%#)()%#(+('"+'(#('&)*""'"*)%#!(%%%(++$#""%&&%($###!&')%$("+
@r1452
ACGTCGATTACTGTTTTTGTAAANGCACCGCCATTATATCTGC
+
+G,E6?:(G2'??7@(D01:5C.4<H6>2?,*8$$#4.#'44'
@r1453
CTTCACAGTGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGNGTATTATCTTACTGTCTCTTT
+
0D51H8C;;#E3(4DA68D$8<4EB%1E/",8C!(1@2771+;($D=)>2*F4E!F99EG(8@?C(A6:103&H4'+-D"8:
@r1454
ACGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTC
+
!46,!FD#;)8D00#,AA<G39@:E;#$A1#C*,,@$63723*!&40G/A0E9B:D8E55+2F8-5(FG:C<.*:-%<''29/&FF5;=%
@r1455
TNCNTGATTGTTGGNTGNTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGG
+
*"''&"#*!)'#')$#("+($&*''+))("%!#)&#)"$&&*&)#+"(#+&+#''!'(&$(($&)%!$''&#)**%$"')(!'%+(*%(%&('!&$"!&)*!*&'"#
@r1456
CCGCACGNGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTNTCCGGAT
+
5>H#F'8G)+<(+=%C,<G'5*89+)*D2D5<96F/@-9G*A;B(@4C:E9@
@r1457
ATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATANTATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCNACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTNCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGNGTTTTCTTAG
+
7&C5FEF:5<0=(,",'788BD+1(#&87*1>#H..D%,'20:&'DF8>6,AG2-*G@A9%"C0;@9$#.09AE-8'5&E+%3D;11*CD<='7"8:1?@G:'&%=#A&#!"G);09.BB*A!:CF.&<+B,7"2<B+(;+6!9><C=>/<5"#F4-&C/G:;0!(4-;HE7)>@&,%19B+(5B/4??>8BDH9!!$?7F82A/,HF!B+$?!-7,+.0&+23%@&B%3G+C'/?H/)#??9D&'(7D:7F
@r1458
GTNATGGAGCAGATGAAGATGCTCGACACGCTNCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATG
+
3$E&DG7D?.GF<60CE4F$51.GAG;*/6<7(..)6,6-68G@<#;G>BAEEF&37486"%B9,*A>;/A8<)E,
@r1459
CGCATTTTTAGNGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGAT
+
F"G!<<F7H59$'()EFG#B.:CE/2-A45%4HEC4,#92"&B5?<'&%")88
@r1460
NAGTCGTGAAANAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTC
+
#(+++)*!+!#%+')"&"*((+($+(("$$(""%%!()(*('!%##++&!&%%
@r1461
GTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAATCATATATTATTCCCTATTGAGGATATTTA
+
@,1(4H+8GCE-2F8E/>A4B%#%E6=94#=G;+#B290"-):7.:(1.D,>?B+?(?&(:&,FB2.7>"*("H!H$:F??,D;,
@r1462
CGGNNGCTGCTTNCCNAANCTCGATTCNGTNAANAAAATNNTAACTAAAGCTCTTGCCCATAAAGCAGATGATAAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTT
+
)&*"(*()$$&&#%$")'##())$&((")%(%)"'%))&!"'"$+'"%+*$!!+%!!%"(*%&"&"()'!"*!(%!!"''*#""&%"$#())"**&+$$$&'#)*+!+!"'*('"(!#"&("'*%'"&"+*+%%
@r1463
CATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAG
+
,%<E$%#A5)!0?+;(@(<,<C#;(,C!#HF";)A7?B6><>0G(,-81E?G;+C''&E,HC0D"$1'(9'"+(D,5+'B$*F!E;D!@/5%,>?C9$22B,4?=B3D/,3,H.<39DG#C4F8A
@r1464
TCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAG
+
%=<-9D?4&<=!(65%%1>%F,G029G6(=3;;D843->771,24
@r1465
TTCGCTCGGTTGCCGCCGGGCGTTTTTCATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCG
+
!%+)*$)%&!%''&(&'**%(')&#+$)!$&'&'(%$""&#*)(+!#)('"$'%)'%$%!!&($
@r1466
GAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTA
+
18'3-<BC.<FCAB#87+E&38<.G"@;;=-6'D(D92((/?E)-9A+$FG6E1++*A*18-#.39#8,DE=4
@r1467
TTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTT
+
.-5F<#():#G+6<*/05-$E14D84-5B&*(AD%5==/3.B1G)BG5+/-F:<12E?,AA@*'+(@'"?A9/*
@r1468
ACAAACCCTAAACAATGAGTTGAAATNTCATATTGTTAATATTTATTAATGTATGTC
+
1'H695CCF24AA?;6,10C(:8<+=A7B7<4%-)0#07=.)=27)E24)E'!"B"2
@r1469
TNTAATTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAA
+
&#%!%$%#*+*$(("++!#'$*%'($%#*&&!+"#')%!**$("(%&'#$")(")')(&*$!(+$
@r1470
NTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGANAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCT
+
!7&)9."@";>8#&&'D>?4DE1":B?+<-;E@+.7*-F%F><:D!;?-?#:#9%=(90:(,;8G'-7;:>@2'&3-;">4F4#;0192,*/>:G0=3492=)2545C=.-/5:C0?*B=%:B1%1D9
@r1471
TACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGTGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCANAGCTGGATGCGTGGA
+
E8A3-2A)1+F<)5*6.4),B,)3G,.A+6G(>"3/)81>B;!:A9-;G$<%(/5H6BEF07+B*GA-D-'((-H1+3C/>*&$DC<%/*,E611</G@D475;<B#3$F"5*#>;8;?5CAD%?&H+-;H83);@'=,7A!%/-=C(45!">A4":2/AF-1AG@$/A2/B$&&,F50;C5=;=:=@#!G)1/>G5GH;C%%.$)B,=:DF#
@r1472
TNTCATTCNNGGTANTTCTCATCTGCTTCTGCTTTCGCCACCATNATTTCCAGCNTTTGTGAAAGGGATGCGGC
+
#')((*("$$##&!#+!#)(%*'%&&*$+&$$#$%%+)!#"#&%"&'!*&%'"!&+!'*!"!+!%*%"'("*$%
@r1473
CACCTCCTGCTCGGGANCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGNCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATANCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTAC
+
D=>>8#,4))14)$43);G89DC;3:&D=G/;3,A'H:/:E?G!)6"#B433+/B$/4+-,:.=0FF5AC*>+50D(<2%=;!F+3G8#2:*D'7#3"3C%GH8>,&48$)EHCC+%1"303!:5!D#':E'A-).5-B)B3!$H;HEGC''0A/7B1(:-D7:C?.?1H'.F
@r1474
GACGAACAGCTGGATAGTTCNNAGGAGATTATGTACNGAGGANGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAG
+
($#$'$(#"%!'%)#*!!!*!$+*"$"+&#)$'&&#&$%!%+)"%+%($#""(&)!!#()(&%+%&"$$')''+"!&%"
@r1475
ATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGANATACGCCGAGATNTTTAGCTGTCTTGGTTTGCCCAAANCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACC
+
"5=:5"&'3&-,<7F(".7*=$E@1;<&6-.D.)6&(07A'#"B8/+D06:,),3BA*8)&,GDC.>3%C/5G;/GG@1&C,59>8E);EC+6%-B-)39EB&=G$<!B&29@?:A(@#H&+>#C$H-4-7&!C:87B7D.(G
@r1476
GAGACTCCGCTGAAGTGGTGGAAACCGCATTGTGTACTTTCGTGCTGTCGCGGATCGCA
+
F68=0<2G$+%!?>40A!-?.A:8/?%C"BAC6?CA(=:'#1%9D>;<2;@+@*6F'H$
@r1477
CGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGG
+
>0%8?$&)*=9)1?;9+1%FA'+0-8C#@-(E7,H>*3(47"?-2>!B-13"!6'4
@r1478
TTTGCCGNACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATNCGG
+
+#(#''"#&)!&#()%"&"#%&!*&*&$$!*!(*$!+!#!&&#""#!%$#$"'+(!)'$+*!$+&"'$+'$#!&#(!(%%#+
@r1479
TTGGAAAGCCAGNTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATA
+
7)2#$F@8C<0#*2.+-+F7(.()(FH/;(-:72,7'CD>("4@3&45/,B(>0/,A4)/)$FA6C=$!HH-H=#226)00<+'1G4H0+B&+7A?E'>3C7:21*H682=A$.
@r1480
AAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTA
+
C#FC429B5><0%&%9#4@@;H*+=!)+=.6A&7DF=F%:3$%$)H'19?;8FF#+@*@<,>=&3
@r1481
NCTCGCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCATTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACA
+
$(**#(+#+(*)%#)!'%"*!*$"!(&&+"##*"#&!)#)*(*)&))&$+#*&$+$%'((%)+"+&(*%$&)*'*"%**(&#!#$'+(!!'$!#+#
@r1482
TCTTTTCGCAGATATAACGGNCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGNTCGCAGAGNTAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCACATTTAAG
+
<-3FA$$,)=-EFGA$:7!3@=D@!G:.H=&("B!2=F74BA/@?33:#/'G%'#1,2B!,#A7#$C@-(1</-&:)AA2G).)7<A;'>;4>1DAE5@4F8@6+E.E4@CH<6=9+);=)D93&A.:()6+7#8?=622F6G!>B/%
@r1483
AACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTNCCG
+
7E#-,5G9AH*;)B4>@EG!!$?7>&9/G=5&)2>D<>-FAE#%1F5A2<9
@r1484
CCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGANCGCTNGAA
+
+#*&&*"$!()('*#'%#)#()%"&+#%)'&*#"')"**(+(*''!+$()*!#&!"#"+'&!$&&'%)+()%#+#)%#"#&'+()##
@r1485
CTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAAC
+
AB?6>;AB<:%6(/-++CBF!D&27#8:D8;&F73.,G(5?(F"%6!>0"(0$>290)>+B81!8&*0F@27.<9-"AAF=;@HG?>*H.1!;9%9>=3%4.;E0;4!*6@?6C:':%G3B&@3)$60G$6;01F&4-4-/4-1-D!+2?6+FB>
@r1486
CAGCGCCAGCGGATTATCGCCATACTGTTNCTTCAGGCGCTGATCCGTGCCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGNGTTTTGCCCGTTGCTGC
+
+(%$)$"#!$!#$&(%"#()%+!%'')+"(#*&*&)")&)$++'%&"&'&"+$(&(*+)#)'%###+"'#!++"&%+%'("++&%#)&!*"*!$%(#")+!"#%*'(+&*%+%*(*!!(#(($&!&&
@r1487
GGCGGTGAACAGCNAGACCCGGACGCTGACGCTCGACCGT
+
+E19,8<0H&344,9G8&G9%F:!1<:@7GB,>95#4H;&
@r1488
ATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCA
+
#GA.75,B(<$86=*33-+4BF,#@?34)+76B6:7F.-"G9.5&F,69<>6G056$5-2=@!!894'H==E?@--8H1/-A*<A%:#>01H03B;+$)C7:C<+A=.:.@(
@r1489
TCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCACCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACCCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTG
+
6'0A":6/A==,'"G2G+8G"&:*68*74F74BF!BG>@+4,9?F'FG)"+55?>2(D0DF$HE@8'EBGDG-'%(<-7+F'?F+#HG;HA>*<<H9F3"1"%A%""E*E!$9)5975(3#D'E<35D
@r1490
TNCAGCGCCCNCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGNTCATGACCTAATAACNGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGNGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCG
+
++/;C"38#!A-6A/G<B$!.G-':"9'9D+A@5/=AD?(/,/397"@D71;B+$#5,B/3;6>'5-7:A1=3@,=$F?=$"3!6'-6%=95)+-D7!;*@*G:#<4HA"#G@-?$E%G-&-(:/BA$$:>(7=??4""%;A-62C.FC9
@r1491
AGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCNCACCATGCAATAT
+
C@8?6@:D&G?$9@6C<%")@*A/!G87%<-":2-H250D(%4$C/*GD&.'C.:3:?=+0.105(4%&,H0=!H4-@."4=%>1<"%9&-%8!)=%0>".'/2;%<915HG%,!:8B*+#F@0>(,:6%"F63@)-=/#H8CCC?:
@r1492
TCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGNAGAGATGGCATATTGCTACGCAAGAATGAAAA
+
H3D:@&<.#(204<'(=3<+$,>0-)5,2C5.2G>2$'@5B,BE#1;8-!+"37168$$7!"G?:/5#'-E?2A1695!2-#"GEFG;5@=
@r1493
CAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGG
+
!9$4G)0;-4H7@67.,,>FA!G!;71?'!C%HDH,2<,A+?E8?%>0C8F2B?,FD0.!-693(.1!+@:G8'(>;<!FB/83H3@118,%F",@(%@>4*:F=C16/?G8CAA?::4@)2$DG7;+?=>)%?%8-FG02=-@EA':H1*:8GA05
@r1494
NTGATCCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGTGAGAATGGCGGCCAACAGGTCATGT
+
&'$*!+(()$*!#*!$)+#**)&(**$+&*!%$("$#(%")$+!!(&$%('"$)'+$%***(+$&('(%$"!++#&%$&)#$&#("!''!")(+#"###%(!$$(%)*#+*#()'&*+)*#!#+%)$$&#'%)'%*&#%##++'&)$('(&"(!+(
@r1495
ANATNGNTNTNACCGNNNCNTNCNCNTNANNNATNNNNACNCNGTNN
+
$!!"#$!#"$!!$#!#!#$$#""!$!""!$"$#$$##!$!##$##!#
@r1496
CGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCA
+
9;5B"'*B)H89/!@2?"C537-D;5)0!4".??)>'2?%(/=EBC-,36&$.0"4
@r1497
AGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTG
+
F(2%G;'9C(6.A.G9A<&:@:70C&:,?HG/A(6G:41-*,&$7(F';F$55AC!H=B"41,686FC9/F-%.
@r1498
GTATTGCTTATTTATCGAAAACGGACAGNCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGAGCACATGCGCATACAGTTGGTAT
+
1DF/"78-/.B*0,%-9,00$*+95.;0#=#!:;1A.(5:*<1=(=B(C/<G'CE?><A%(&B(B:(9.G&717"G8(''4F;<,5'$=>72%<0,,-%)
@r1499
CACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATNCGCCTACC
+
6'E7>(G30271?C.B+-6*A2C?CF$@+3"A4=7/0/<3/E1%A.)H4"C7-4;E0&".)FA.A2+;D)
@r1500
GCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCT
+
8&8?@*512+#"!:E<@?)5/G;<9,7;#20?F$$+E<:?$7B2$=4&-B!<<!6-?#)*><&->1B'1)1F&=;<C;;3AC8;D>F$7"*;8/6;BFH0/A7.@>>A05:@55.'B#%*3#8>EF?@-HE@&?)/;0/92/6?200H:D6"5,00A)H>@680B&5D;H&H*C<#;,!*"AD9FF:'=470GD;!+":
@r1501
GCCGGAGGACGCTTCCTGAGCTGACGATGNAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCA
+
F:@.52)5FHBD!D0"?F->$%0<"BF%,!=8($(.,7C93;1A!37!GE3>5%:C?8C;@!B@%#6C/&?1;5$:*@,;>>@%8?9:(*)?@4E;@*=>B;62.794$7+6E+BE#8D-86A?=&!BD.;B<,*($F0!<D0"BH39%?0&'%(+*.7=9H%)B!,G<-2'1+B*5H>6/%FG33:?@G0:GB%GH:0E6!2*.A"BH@
@r1502
GANANTNGTGGATNTCANTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTG
+
'*"&"&)")$")%)+*''&"''"(+'!$%&&$)+!")$("%%*+*!&"#)!%%%(!*)!(''*'%$)'+%)("$$*$')%!$++('("$%%(+$)!'$""('%(%#)$''(()#'(*%')#'')+
@r1503
GTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTGTTTGCCCTCCAGTGTGAGGG
+
0!65<+$0:>:>?<G<2"3;'*1--7-E0H@#,G6(==32,F>H-C<:A1G34BG=H10(,:FDE?<3+#$
@r1504
GGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTNACGTCATAA
+
1<223EA(A1C''3/75;H"#$@'C1H;$HEC?H&,3C:*'4698605B)G==26$
@r1505
AATTAGAAAAGCGTTATGAAAATAATCTNCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAGAATATAGATNATTTTNTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGT
+
)842!)6(1G+:9;72=CFDC-/'0G79-77"F,6C%69@0A>/#&"&).,56<*27B%GH4<D(1*H'?@>"1@)02%<B/("8G6!*%.8#*C2@'1*7<8"%<HE@GA.C@<%'EFG7<GG=+:H;>26*+!6><=-4@6)4<E97<3E=8#/(95(F5=7',2GD)C>5%'1=9?2(,$313,@<(->HE!!(=
@r1506
CGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTNAAAAACAGGCTGAGCACGGNGTACGNCAGCCCGGAAAAGTGCANATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGA
+
7()>8:BD$2%-7C;:BHG',4",@"?08-*CA5='68+(1F;7$-6H89F')(%*"0H.>C8/-,"09G!+;AG0C,;D,!#!6=?D/<9"&E%*!;657?4F*A$8%01.89!8A2270+?E#6F0GG<=A9?<3?C07/$&HF9:($)2$#;D00(7;+:?-HDB9:;;DF"6?;F.3(A5+2*#6436,CB/46+DB*(8+47
@r1507
CTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACC
+
8#H7A38?-@8",E'A@F2FF2"!37*A@E)D$+#4;;4<;/D<(-(1A?D!4!0
@r1508
NNNNTNATGGCGCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCGATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAA
+
""!"*&+'%%%!!'%*&+"*+'()$"*()#+#"*&+&!$)$%"++&"+&("&)&)&#)#+$$&&(!'!!$)&%))*+$(+)''$'($"!"("&'&#$"+#($)&&$($)#!%*$$%%)((+)&!!!'$)%(()+&"$$$')+'!)'$
@r1509
CCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAG
+
251.FC<=;+AD0$)@#B@)9'>$C1<EA8C8$-2$FGD;2G"?<1(&%+,D?).+)GE=-*')GA1B>7<>+0:+;%E<3)>CF!@
@r1510
GAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATC
+
>.=0!B$'<.F#2"1300G1(/'45G6+,"806''<A5'3,&B3EAD*'C4*.:)EE&/BF&H
@r1511
TNGNTNGCCANCCCCNNGNANCANANTNNTNNNCNTCNNGNAGCNGCNNGCNNGNATNCAGNNNNNCTTGNAGGAANGNNANNNNNNGCNNGCACCAGGCGNTCNNNNGAGTTCNNNANNNNGN
+
"$!$$!!$"##!#$!###!#!!""!$""!"!!#"$!!"##$$"#""!!!"#$#$#$#$###!!"#!"!"#""##"$"""!"$$!!!#$!!$"#$$###$$!#$#$!"$$#$#""!"#!"#!!!!
@r1512
CTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTNGTGCATCGTCANAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCNGCGTACCGGGATCGATGTGNGAGCTGNCGAACAGGGGGATGATGCGTGGCACAANTTACGGCTCGGCGTCATCNCCGCTT
+
*+'#%)*$##!'())&+#'##$(+$##&##+(!)(#*"#!((&&%'($(!!()+&+(&+(("*$)""*)!)"""*$&#)!&++&'!"(!')*""(')'%!*'+#('"&%$''))++)*"*'()$)#+"*''!(&("))*%('!)!%(#%!$$!*$%&"'&!()#)%#%*$''(%#$!)&!+#'$%'#'$'("#(#*(!+%"")+"'"!(&$$)&%(#!&#'(**"*+&(
@r1513
GTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGCAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGG
+
/9F1!$'</":H=C/1B@1*,+&G>&5!4.#-1B-#1%)H@H3#-0!0AF>=H*H?9&&$%CDF'<&8$E+=6B)0)0#;CH>7>@G%*5!$.,2+
@r1514
NCTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTAGTAGCAAAATCTGGATCATTCCCGAGCGC
+
&!)(#+&&''$"*+"&#)%&''*()*+#!$+))%%$*)+(#(!$)&$!)#"!+*+#"')+++*)(#*!#+*!&)()#
@r1515
CCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACC
+
<F(/0%-91=013#//(+>;83(!?@=?=HDA=E)H61.A%(BG
@r1516
TGCCCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATTTCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGNCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCNGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCNCATCTGACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGGTGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCA
+
(!!!))+$+(%$#+))$%*%$+%$!$)'#$%(!%&"+++'(&!""&*"$(*(*!*+#)+")'")"$)+#+(%%)()'&(&)%*""($#(!!*&$&'!+!!%"&)"!$$+"#!*)%('$*!'*(')'+!$!$)&+%(#(((%*!&%!&*!#$#'+*'%&%#'!+('+*$)%*&')(##&$$"'!$!##'&&+(&$#+!$%+!*%&#)&)#%))"!&+(&&*$#)"+"$&)&*"%)!")#'')*!'!#"%*'&'#*$''+)+$(#"!%")+*(+'(&(#&+#&!%(+"++*&&''&*#&%")!'#"#+"'+#!$#!)$)+*+&"'(!'+''!"'#)!%"+"#(#$)!$))$!!%&!(#"+((!)$''&&*%)!'+*(
@r1517
GGCGCGCCTCGTTCATTCACGTNTTTGAAGCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATNGAGCAGATGAAGATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGAA
+
,)H(43-?2(FD29'48F0<2H$,9#AAB;$2G)2:H'F8'A$B=4&EEB=+*.@C<-HF-5/7&"HH,=!,,)B8H-,6(?!5H(<::?E#.E=3"/C?A#HD0<,39,2B?2<7!!>%'7&":E&;'537$ED16CF?8@%)2@
@r1518
GACGACCATTTTGCNCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCNTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGG
+
CA4?'3E+@7A&DD4"(&H05";"G?$!),.%5!G)2*9D+@&!A06;)869@'#;?/6&H&H?"EAA*,F)"264.3*4D3"54D&$')&-7G0*7)3;+2.(,4AC,!F*%3?!$,1"E(">4>3.H58%$HA%B@-?(*(&96>)9GC7"
@r1519
GAATAAGAATTACCGATATCCATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATGGCAGGGTGGCCTGTTGCTGGCTGCCCTTACGAATCTTTACTNGAACGAATCACCCGTAAATAACGTGACGGATGGAAATGCCTTATCGNCATACTTA
+
2#DD&2;!>H/+&96-%CB$6@=9'B*#.;%3B#C/@B66;>&@)6*/>-B@)D#A3BB@)($-HED>*32#8GA<>3971D;5'-"?+:67/)H7.69G($4A(>)7+)G!32&:24$G28!<4>1C(/'6-6HF?2&C75GE488@(;456;8E9H+4AC)4.5F4<G17FA!003;0=4+;&@>0;C$$6:HB:D#*F1A2,78$0%+2FAC$"+G>=!"2D4!2!/@BH%)#3-+/C9:587"D53D@""7
@r1520
GAATTGGTTAGCAAGTTACTACGGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATNATATT
+
;"FD+),>E0G#:#C&FC,@+%$D-"D=,.D$0)88G/,5,+BG.,%BHH8)E4&6;54$CG*>.@7&@/?::4-9/)+7'<77),496:@/#AGD83H/,>23HA&"
@r1521
CGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAG
+
$FH1;3,,7#5'F,%059#-,@72=%!:*'32HD:38,E/=*ED("3!8+25G%8&G:@-.#5C;%G-<6C*>,#"#*;5="A2:%."*9H(#<6.C0
@r1522
CNTCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCGAGGCTGGACANTCAAGGGG
+
%#+)&++''*#%%$)%)"+)"&**+%!%'%*"*$$"+%&'#"("")"$$'%"%#&"*+!+#&#+!*)$*+!+#'#)!"%!)!&*"+%%*'*"!'($)**""(++)&&&$'+"!"!$$$!(&*''+'%#(&&
@r1523
GTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGAC
+
1@/."8>@4'$D91#=!:48AE,,E/6D+8%3+#"4%29&G%!+@5G:"HA))4#9+@>A?::&9!(;(/<3/A,>
@r1524
GCAGCATTCAAAGCANAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACAGGCT
+
.0<8)E>$@G%690*-=29H<2,@GD34")'C1B7*>/"%?2G7,%44:1#3CE9(+@%&0#$;-44<2+45=%#9%()?E>#=C1<#H>1C661&A&(D<12::!9C:22-1F,A,;<3/4?+,$#(6@@.4*./-)1%2,DB5:;F7"9;-=8;)0/E/&B0@,9C;$$=@+G4)6E6F!1"1&E3A6C,C/G+?F'C0".76.G9
@r1525
AGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCC
+
8;=#F6)"F5G6!%3&#-/:16;)*746872@<EA58>6+*"5)8*6%?16?-GC0:F".D*EAA,"H4'@2@3.#3E?>4!2'1D()9F2$*G'2;+"4*C">GC)H8B9%&
@r1526
AAAAATGATCCATTAATGGCTTGGGCTAAAANTTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTT
+
,1+472E@)$@DB3#0B/4&6=,H=//:4,*.7>5"5E?A@13A>:DD1H@(B30=B5"$'-3)<E*.GC/5EF/79A5)FBB(E"C8D.&<G=%(/#F-1*3&5H%237G>+84=&*9D?#4-))6+84F
@r1527
CAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATT
+
-B'25-53*,A$CB*'.A7:''"5@F(1.96/6<H!,&A74.!!&/E/E02"/08/"#?&**B!8E@B,,0#+&)B1B@.,A(3=857=))8F.9'",'(0
@r1528
AGTGTGAACNCCGTTGGCAAATCGGCATTCGTGGAGGCCNTCGGTCGGGCGAGCGNTGTTGCGGAAGGTTACCTGNATTTTTTCAAAGGCANGATAACCGAAACCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACCGGAGGAGTTTTCGAAGGAGTGGAAGGAT
+
5:<.328<92@46<)+@<;7-F'H3?9!@7EG322%'%/9:H25#HFA$9%3AB*>H11>@,5!3<$72DF:F*$@?&*-1B?C920F;H*F!E/%1!!5>)'$%/(&C+0E.0=,&/=$,G'$72<&=;$660*,FH/<+6-2!&1B?4"0>%5?1<+@>>5(=CG90:7H@<6'+5F.$F/)+F1'5H$/
@r1529
CGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCNTCCTG
+
=?A'?'C<8)%4*+0EB&B=B?0+1/94(2D*;AA4%7H?(CD#6&=/9:;5-?8?1AE+A6D8.@&9?2F;(C;?<'B<)"!*+E>63B.0E;&;5C""%$+B"<.3'CH'=2'*B5)F0,7B5EH#?#:@%C26?#@GBA1F$:*!.A<B!%6:05B6
@r1530
TGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGA
+
,=+H@H&!7A0#7/DA,G4=*+3.6H*>C'95B4?.)G<:<4/'/37%=95F(-<1:=3@+G0/C9,(C2$=
@r1531
GCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGANGTAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTT
+
-<(?4:='()8$'59:3/+,0(9/E-8-H+$1FH,,(/75.9(*)2"@H>=2E&9+)8<"A#*2.3;6C7FE2$=9H9#;D6>,5'045E0%613+;*D@6+2#C5*4:>D(;3':>'3"F"<5<BD(F:/CA'%1F/,/42-/6E8%6$%/$205&%@$:."?A&H:/BC4=1D"@)
@r1532
TGTATGACGGGCAAAGAGGCAATTATTCATTACNTGGGGACGCATAATAGCNTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGG
+
<-2'EF(AH,3$*?@E7((C=<"A1:4/"?,$*,/-1::#A,@,8&+!%1:?.<C#$)G&%-B0A"#@"B1;?9"4%3-2%7($A@!$87.DG,;7;>>&DC2G,(/&1
@r1533
TCGCGGTGCAAATGTGTTGTACAGCGTGATGGAGCAAATGAAGATGCTCGACACGCTGCAGAACACGCAGCTG
+
0(D+:E@E;/'#*+:.68-/D95;7-$3G?')8:4;&<,:C?'?-.%C$;#H@*H%G!?/(F$<4,>CD6A10
@r1534
CACNTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAATATGNCCTACTTCCACACCCTG
+
$!'!+'#+(!$**$%&*#'"'$$'#!('("+!**"#+%+')("&&#!&($(**'$'##*($&%&$%#%)"%#$('$*)++(%+)%
@r1535
TGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATATAACAACAAACCATGTCGCTGCCACTCNCGCAGCAAAATCAGG
+
&B!A"=D?&25))276DGG#B09D0F(0"16#=0/0<01&@)$.E;.01?244D%1%D,2<(=64><8)DE";87#-A8.?/
@r1536
CTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCANAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCNTTAAAGCCCCGNAGTTACTGGATTAAACAAGCCCAACAANCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCCTGCGGAAC
+
,0-8)9*3/,H<?;?9!9B3:83*07/F9B!<<8A72*:#7'&H83?--=#3D.F?;1?"!,#91.*A9".=>(!@$6,1?".<:3593*2;)"E@7%1"0E5>GC1$=H(H'!G'?B&##677*:49:@?)(?.,+@(C92F'$<?"$8$E657-C$<"@56BE5&55D6C@@@5"<'9+0##/EG1/99166;&"=/&?:4%>:*5>;9+,,/<G@F83/*H/8%4@@*=!#
@r1537
CAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGT
+
-:?:/E/9<7D;"=G07-(2<AF-#G*6/-)/!!?>B,6#)G:A2?DD075;$1#$(08185)D:+,DC!G)1+G$."24407==@E4
@r1538
ACTTCTACTATTTCGNAGGTCTTTGAGTATCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTAT
+
:B8?!D)A'304=%#6.&"H.H:?+=,(.!)'*A?C.4.!@2.5<D<A&BFH:4856CD!;H!5(CF#6(9:;/23;E#<=?8D.2?<@
@r1539
ATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCNTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATAGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTNTCAATAGTCGTAGTCATACGNATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTACGAACTCTTCAAATTCTTCTTCCATATATNACCTTAAANAGTGGATTGCGGTAATAAAGATTGTGCCTGTCTTTTAACCACNTNAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTA
+
@%<E-6"+3@:&F=?B8:)+-'!F1@$8BF*3>"-CCE47.'6@HA$(?6)<CFBE%.59442G08A*B';B?1A7G1E,$">+178?#E5H65G,/!:E,(8/%1+5H(1;>;4:;A90?C;%H',$-&>(7E1$;861'8BGC/FFD<.?;=6*97:%H(=/HA?9/&F;-&;8G+%""*>7-EF#%3D=G@1;9F5#.AD:A=,!':0/+)$E01G=DC;68?"8=>+3:F):024'CCD@3BB!'A)%BAG,/>E>20/#91A/#=91$<@A)0%DF<4-<(*45@1$"(-,8='DH=/?,4&82B*H'%A=-;E=)HD3/'%5,D-02%03%G>6B.AD(5EA><*1<78B!"@0-=5#;'2!'30BABDE@BA$G6>.*23:4&=*:6;#')01#"/,#4<?2E1236!="%)A)>0>#<#522<H3')%'#2#+%54=)$B>G%$:7FE1,$1,BA.(F8,(/9'@,+A)@D4%#G@D
@r1540
AGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGAG
+
89F.;"0D!F,38%<.=C3&)"4%72$9'&:9+;>CE(<7
@r1541
CGGCATGGAAAGAGTTTGCCGAGGANGACTGCTGCTGCAT
+
62A-B;-H';D3&>B!#>&)41--#+'G*6(<+@&C#7F0
@r1542
AGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGGTGTGAACATCCAATGACATATNGGTTT
+
92>A>>=/'6EEF%<.H/#E$(2F-03%6C=G),10FC1#/)4(-*A0@0+B*4EHC'4-(,8"0&:A!#!/#:
@r1543
AACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCA
+
>=-'.,E,A190:&BE+E%$=2=9--H0GAE:C*;6<@$6>"/@.7"*:3C/<(.42%F)C'-CC%G
@r1544
AAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGNCTTCGTAGCCATTTTTCATAAGTGTTAACTTCC
+
G*<"G1A5:G-!*'B61GG<7BE*G*8*?2*-5-/2!(3-,=55,5@A7H0<A#0+#8H46;*:@1863B)@A
@r1545
TATTCTGTGTGCTTATGCTTNCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGNAATNAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAA
+
'A=1>H=8/C*8D/@*@'50';1<%0&&G>&,G#,8/11#BG==@53&&%1A,*850?:=.<#$7)(AA*%4H0>#-,<>)+)2?=A>.9!9HHG(%F3&.!:*6!4081->#92#G93A5(E1&!.H$7@!,
@r1546
ACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCNCGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGNGGTGTGGNG
+
9/@>8=9-D:@B"7@:'%'9D>&;-C0$2C(=:'&5:0&D#0>./*86<AC"B<A9<".9DG>213"C/C&5F)=4+<!6'&D#(B*@C$"&3@+)8)<72,;3G->:(FG&D=,%59'(5HGC(/9'D6-08#F5'$*?+"%*G178;0'--;,044E1'4)H(B<
@r1547
ACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTCGATNATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCNTTTGATAA
+
-%4@252"+0=112!-F2C,?6A0.3(=-8"?'B4&&=.:0%6.<#@>,:434,2%,$8BF98"E+=5#?1#8H,#$)!"<?6=-:00<-CEG0:D,"#!.5DC:93.>;/+=E
@r1548
AAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCC
+
B/02>+!#3<H&%#)093&094#;7<0H%&9%?2(<%/4-+%=%A0="2*,G7F>??63&!/<907!$D7#"-&937#>-C#=&A))A320>/C(D6H-52.#8*'(;/%0*.',D;$@
@r1549
NGCTTCCGATTTTCGCTTAATTCAGCACAACGGANAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAANCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCA
+
$$H5::29!.@&$E"@#.=5=B>*AG4"0@H$9-@>0)!<,7(%6A+H*;$02?EF-;+-%%'E8G0?8;*,46E1+#!+#58'8=65F-:FC;'49*C708E2,F;BC/E<FH(1?;3!@D?18?B;HA:0C:/((%-..?5"4A%A:D5%3!@63("D)/CG%7,@@1H3$%44D
@r1550
CGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATNGAGCGCCGTGCAGCCGGTCTTAAACCGCCCCCCTGGGCGGCTGCAGCATTTGAA
+
D5,>C$G:4&C++24)2:,<?"5*?8.>'?)':#/*:':.D:?35$84@'@%6C!-)00&%.D18A23:)G/,%+DG47G+@@3?#2/:(6?62*B-%$0?C)$*2<.%@EH
@r1551
CCCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGNGCCTGTACACCGAAGGTAAAG
+
#G*5CH+&A>#$)4*303-6(*,(22D>'3'8/65(%8;45EF%/?:B8@)(0=)2F386%*':$31)!5;E*8=/D<9'0$.E#;C@-8.+8,6E<
@r1552
GAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATCTCCTC
+
#9(%2-435,)$40@F*C+3C+A?(8*8&D#0'::@73F>0=!>CC=8?+=-"$)C*2>>@6GB8/$++4<?
@r1553
GCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCACGGAGTTGACTGAATTTTTTA
+
+$'(%$+'+*$$)!)'$"#+*!"&&"&#'()!$%&%'++(*'%"!('!'!'+&"#$'!+*!+$'&$"*"'*("#)'(')#")
@r1554
GCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCCGCCCGGATTCAAATGCTGCAGC
+
/(/.<;D0D!"<20"6&(%&<=#*.4,H@'((G@(&*'1'3E!!B0G#;B%/1:E?$27D4?8."4$".B*HA(75:'9363:/
@r1555
AGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACANCATCGATTCCAGTAAGGTTGATTTGGTCGNAAGCGG
+
(+((''(*'##!#+$"*"&)&((#'#+%%$+!'$+#)'!$)+*%+#*%(%"!+)+('+"+"++"()$$#(&()&+#%+#(!!%#&&#&(+####*+"&(&*++(#&+%+*))+*%#&!*"&)$($%&'!''#*))&+!'+&#)*&
@r1556
AGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGC
+
B<66C)E)$3G'FB3H;G34CH9'>--""?A+F<&9-5&582?'2@::F6:5%01
@r1557
CAGGAAGTTTATCCACAGTTANAGGAACCAGCNCACAGGGTATTGCTTATTTATCGAAA
+
@&<B8+#?($;,%=(?90E":7CC(97A8C7@BA;*&:&$96!D,C0#32<$;21><6(
@r1558
GGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTNAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACT
+
%,DB3(>A=:)F$A":FF3#&6-@B56%.!%GG:@:6.="$#>?E?9G@2G$A"D$%BF:F2G'22/.:+-<4?,+&924CHB;8$B"6%&D"@>C:FE<=1:H#.H8"6=F+A'@
@r1559
CACGTTTTNCCGAATNTNTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTNGCTCTGCGATGNTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCG
+
5#B2A6*+*@C+28>;>-,D31>70&C$':2G'/#6*)&A)1EAG$37!F*D@HFA!+&5385!,$.)*91B6)5&BH7=!&48C)#;<-4#0<0$@FB&,6B:,0?3+:D2;!A-"2?-*->:4".B>
@r1560
ATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGGTTTTTTCGCATCACTTTCCNTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCC
+
:;8-:5"@4)>=70$B=8!H+'?&0@$!-'AD,;?HAB-&E1F?A8:.*HE)*$;=4A;E"28BE:9&-'%(($'F!3)%HHD(H.>@C@;)8<?G$G8<!2+)H>867<D-/,"($8<=:<#1)CG@D"(%7,!2#*D-61H4:+B%/;!4?4%-=#;+#@?<5
@r1561
CCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGATGGTCCCGGCACCTTACACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCA
+
818B&4'//*!(;'"'<G>.2764.B(=H./<@FD)E(9H1@8>D#1.9,?7:;!"C*A,AH'4.!?1=HF1;9#A23$F/+77&C-'4?@0&:@*/&-<,/@.%=/).?E7"<:.E0D'0&D."/G3%;H>B;:D=G#590:7/1!/6.?"B!E12/:@*?,@D.59:D983.(DB*/#+=-0<<3D3#G+0%BEC"#E'C07168-A(*0+;>04:&=8,1#:'::#=8",6A$$3#/6+1&7@H'!)>9$$H0,%:1;CE6"4HA@>DA
@r1562
ACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGT
+
6@A#!A@"ED(A67>%G$&-?>"#//-C%>74H-E"#"E/7-88?>81!>#="
@r1563
CGNCNGNACGGTGTTNCNTCNTNTNANGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCCGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATG
+
$'#&#'$#%&&$!"%$%!))%'%)$*'&+++'!!!#"((&%$$')+$&")*'()))**)'()((!%$'*&$(()#**#!%%"(!(!#&+&$!!&#&$!("(&"(%"'!**)+!"&$')&%&*+&!+)("!+"##&((+!#!!#$'''+!
@r1564
CGTCTNGCNNCAGTCTTNNGCGNTNCAAANNCTCCTTTAGCGTTTCCCGATGNC
+
&')*%!)*%(&)$#))&""&)'"*$'%"'$"+'$*(+#&)'")((("$+)+##'
@r1565
GNATNAATANNTGGTTTNNATCCNGTTNATCCATTGTTGC
+
&!*#""#(*$#$(($**(##(((')'##%)"%$&"$!&$+
@r1566
TGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGNA
+
;$11$878)/55&D?42=<??:,'A85,2EH@?+(;G$0@4!1;B(3F.,2?&,;47,D(@*!B!%9C<H2)-&>2F:";5>=F<2/7B<"<&7C>1DF-<H)%>;$A2%(E?="48%524D'<%$%/,B!'#;B<H7AB&/
@r1567
ATGCAGCTTCCCTCCCGAAGTCGAANTCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGG
+
%<A#8/,=E7?+0->-8*7/-%-2=G?H<:/7/17BG%%9?F7DEE>D/C-182E=<((+C0B>-4F&+8'!CE$%/,8,*@:HC*BF"7%+@,-61<@)*H:-"D9;-'
@r1568
TTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAA
+
7)1&9@D;G8+"0F$G;H.#%6$."A%<@,$$"=!1CE7EHF,C"4)CA<
@r1569
GCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTNACCTTTGA
+
.*/B4EG?"50--&5;+,D%)(&3@+>F>1/6'?3>-@&?0B=E1&=$$8DG
@r1570
GGCTGGTCTGCCGGGGGACGATTCATAAGTTTCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCT
+
8&&#G66F94-B+#+8@4(D1#293>>))@255.>/A?0&5%5/!D7"!D/6B/C-D?;'ED8.509@5(61B$E!=$BA3&&:*H<*E#/3D;F()-8H*C441.#
@r1571
TACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCANTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTG
+
*1>@/=:,F+=G%7%/A3)1,-EF&,'AC*-#-3=5*FGH2/*B26"7%8&B(/:;8/$=:-1H-*%:%,!;+80/93@78<>H&,0-*;1!,=FH,F>A:,4-G9'!:+F/<07455>3<@
@r1572
CGCAAGAATGAAAANTGATATACTGGAATGTTTTAAAAGGCNGGTGGGCAAAGTTAAGGATTAATTATCAGNAGTAATTATGCGGAACAGAAT
+
+''"%&"!'#%)'&)!'(#)%%'!"*(+#!%&$*+$(#+"'+#!"#!#(!%%*')"!"*+($&'%'$+'$*$!)*%$(&#*+%*&"!'%$*$#
@r1573
AATGTGTAAGAGCGGNGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGC
+
.(4.0@7E/3A,C8A;;7;-4,2'$,F=B,%<"/,F'6*!@E&@3/B#A@4/1&&C39.H5@&EF0&@3*9=H,FEH>?2#0C=B5?DA(B,'"*(627H);'&-D@C#&BFE76-"EG@-2471@.:,@'1$/>>@2+$;B/%#B;%28):,2)85,C)3)22B.:<)#'CHF,0#(5C((9D;:35E'7-3>!@5-C-2.'H9</H0.H<$@>!5">,H(>!$!&/&GF!#-HB'.</D4
@r1574
CGGGGAATATCAGGTGCTGGCGCGATGGGACACNCCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTNCGTCTGACCGTAACAGCGGACGAAGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACNGGCGCTGGGGAACTACAGGCTGACGGTCCGGGCGGTAAATGCGTGG
+
F1EA;:'5A9!<218543'@('.,.@"%G=1AGF7H.(>;!&)=:8@,3<D085C,,6,.-7*GE'>BC((-+:<8#%6!%G64F"2(")>H0C*$+-3<%)@6;<:).7'H/A886'=A,G!1?22*,'3;1B<,-4$%$%;%D0)!E2$.+))=(*-;%G$A%E8C!AHGA)7*4?B7"@;F<;3'*H@C7>(BF4)
@r1575
ACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACNAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCGCTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCA
+
?1@"14-2!&8<;E(-67$?%3-D/)B$A-1C7&=%1",G%@F2>2@A='@(!!A$-00"D6:292)&--C55,7%/$7"*!=;1A$&B#D4?&G$7@%))"(.0%:?=F1DB%!?@!<B$3>'87+5!((0
@r1576
GATTCTGCGCAAGGATGATTATTTTGTTAACGATAAAGCGCGGGCGCGTTACTGGTATGNGTGAAAAGGCCCGTCTTGCGCTTNAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAA
+
+&&&)*+!""')(!+!*'!**&&*""(*&$('#%#%!+$)"*$%%"""!"%)%%%)!#%%'"+'*$"$*!"$!"&)+"'"#+'(!(!&$%'(#'#!'+$)%&"+"%"#$"!#(()(**"''()#+)')+"%*#*+#%&'$*+#!*&*'%$")*((#!%(*"*)&")""""!(("'%&$&!))'%*#&+!!
@r1577
AGCAACAGGCAGGCGTGACAGCCAGCAAAGCAAAACTCGACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCNGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAA
+
%E39ECE=<C!<@!"08/3.&E&7+,&&<&H*0'D(@3:#"4F1*,FHD>/$-$<-D@*%(!687H)?H'/B?E@(/08H"?(82)9C;=538+85=C0,0$&.0=441*=):H,8-0,%0+9;=%=,'H!%&D"(>&+B23:23F249.5"/-)08@8*1407
@r1578
CGGATTACAACACGCTGATGGCGGCGGCGAAAAAGNATTATGAAGCGACGCTGAAAAAGCCGAAACNGTCNAGCGTGAAGGTGTCTGCGGNCGANCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATG
+
A:&'E.(:;<?(8E5893"5EF60?>822E762:<#*>-14:A997(6D,E+F1B*0)9B+?F+=,F.6.#D1)@'=#$(<H8,/6EG@9:2#<C'H#@D">)E<;;)EH2,'*)$34<:96)%.)#+;(.9/4/88H(&!'+0?F>D9(?.)26*7-(1<CB'")--6:;'0$E+*
@r1579
AGGTGTTGGCCAGCATGATATGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACATAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGNCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCAT
+
(//>$%;C"91B-.!G3.2A6H6F"-B5;!2*(&86),!BA&$,<3E=""'4#@/;=?@EA:,C@>>#2689(=;4%7=(FD?E24C)#+9G(%'B3H3;8/:A#+A35>*!-;4GC6EA45-*0G*HE+/4,G>@(*(;"=404A<,E4C"2>:B-&=D5/0!H/1%("#?9=)D-F9(--)?92.>./9;3<*5-#2B0#=B.#C?D!H?.8':AC%71H2H47+FHC11:C;
@r1580
GGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGC
+
;3?=!,8*+;=*D<@1<@DFA%CG%3.8A5:%>05936'97*487%"@$DA2*?)#
@r1581
ACCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGNTTAAACAAAATATTGAGCGGATACGG
+
-="G*;&D<(!.1;0;@2-*;G;B/AHA2+?:*-#98#6!/@5/H!)$73;E11%0=8!8.@"%F)-'1D@8>504D4AECA@G
@r1582
AAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGNCAACCTGAAA
+
*;296<D2(H&#9887&<<,C'DD<6(:9-%F1%#DE"E7!C219G38)$/81:.+7A>"!5#D
@r1583
NGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTANAATGTTTTATCTTACTGTCTT
+
&,B(%2B1:B*G.'!E(BA-<*&091A4#$;70'>C?+:-./0+$1!(G145C3"&#D="B?>6D'F'/5%(&"!<>7?0@?-.@&*:(CHH&$
@r1584
GGCNAACTNNNCGCTGAGTCCTATGACGACAGCTATCTCGATGATGAAGATGNAGACTGGACTGCGACCGGGCAGGG
+
*(($())&&!(+*'('!*+'#&*+#))&#!&&''(!)+%#%&))+!'%!%('""+#'"!!%"$%"*"!&%%*#%#%(
@r1585
NATAANTGANNGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCAGGCAGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCANCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCNTGGGCTGTTAATCATTA
+
"&&$'"$(*(''*(+%#&$!*)%)*&%%)$#$*&!$%'+%+#$$($%!!#$&)!%+&%+'#&+$#$#%%"("!'+*"!"("%%"*&"!*!(#!%!*(&*%#+#+%#'!$!$")!$%!!+&"**!&$"&#%"()+"%+"%#"()&+$"%()'!!+&"'%"!)+!$$%*$"")'+'*&!%(!"'+"++#$+**%%)##"$%')""**&"(*%!#+&!!&$+!("#+!''*&$+"(
@r1586
AGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCANTTTTCTGGCAGCGGG
+
+G4::?99("=GD-DD.H%,5F,D3#!9:4517!@5'<=F4,4@(>G4<7%)+3@3?#",4GFC"'-4C))!#)9@(;=>1-7$
@r1587
CNNATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTCATTCAGCATAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCAC
+
$(!+$#!%+&((*("$+&*$()&($$"$$('&'"+)&*(!#"$&*"*)$"!""!$##&$**)*'$'$+++&&$+)%&$)'*+!*&)+($'
@r1588
AAGCCCCGCCAATGGCGCTGCCGATACTCCCCACAATCCCCACCATNGCCTGCTTAAGC
+
+9D62!27*&2A@1,?",65+G&CH,.C-,+(H9=1:"ABG<1&<"A/A88'&%6*/24
@r1589
CNTNTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGCGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCG
+
&$)$+%(#"&(*+(*++'+(%"!)!*#)$('!#*!"&#%''#)()()!+(&%+))%&'%#*(!*%%*#')*&$%*+)"'+$+)%$)(*#"*&&!"'%)(((!($)%&$"$+)()!!&'*+'!*+&(*)"$!()&&('!#!##
@r1590
NGGTGCTTCTTCAGTACGCTACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTG
+
!E=#F0BEG-"'CB4$;/+EBD=F68&(="#3&!?&+8G+&-':-"D.H?).B**8C&35%%0;B?C@33H(,
@r1591
CTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTTAACACACCGTTGACGATCTGCGCTACCTGCTGTT
+
?0303.H2<H0#G=G9E57!C$AF#GE&B<C+'<(D=&9(;'',&/8D79$6A9F07BA=@DE5..4H1H6A$H".1+GA8?02>D&)DB
@r1592
CGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCNTCAGTCACAAGGGCCGGCGACCTGAGCA
+
2B5&@241"8C(&(>63@85&3,75=%"C7>"8+;?D7>4"7H$!@:5CE@&,E9A&&8#*B-?-)&6DG@09*;,5C:"0.323A/D-#.;*3?.*8959+@!"0CH'>-$'6!=:-4G5F/F2HH&6F6@0A$6,#@-CC13,5%;(92H!(GA'19'&'7)"?"12%,(%$D&9,$+*.6:-7-256HA
@r1593
AACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGA
+
9%+/;6'D.24@-D1/90;'3$G#8.@&3:#"19/D$;&<A
@r1594
CCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGC
+
9'%D5&?0"!H754=%&G.):E>/;#*?-H>@=F-%39;BC?0GDAGG"!-(/>@3#=*+'F0#*D;.<8B
@r1595
NTCNNTNTTTTGNGNGCCNTANNCNTNATGTNAAGNNNNGNTANAATCNTGNNGNCNGTANNANNNNNNGANGNCNCNT
+
"$"!!$!#"#"$"$"#""#$!"!"!#!$!#!#!$!!""!##$#"!#$"!!#$!$#"#"###$#!#$#$"##!!!$##!"
@r1596
CGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGGNCCCACGTATTTACCGCCCGGACTGTCAG
+
1*H2#G!H.DH9F://C)!.;.3:!F;9)$A='D87+BG66=5F(#-).H@9((=.5=6FC!F$8"#7E15$>:,27H@GE&/1
@r1597
CGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTNCCACACTCTGGAGAGCACCAC
+
F2*H+G:<"#.%=-,!<0&<6%0/@/5?18C==02<B<32/2G'+85?:1=%6*A35?1522%>.4;2D77E'(?25%E$(/57*$0%6<+E,D80943$)5&HH0;G$F3=FE=D?!8H61%B2C-:"'GC9*0:)?*48*$</'(7)"0F*0EF.2A/38?1'>G,D$A#'7;6!3@9+1"CAC.%FD9-E:D2A(?42$=5!6#>?AC18
@r1598
TCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTNCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATCTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGT
+
F'E$+06!-;491>5B0?(>?0)E$HD8*66C!<>G26A$H<.<*956HGA;1604D+6'#00#A+53'+9(;"44!H(9'C)GA(<;:4=3,B04GG+::4:@AE7B:7D716@032B;%-1(:@-G159H157?,FB6D#2E&"%@%A4%<@-F60&4D(7,,D47!D;-$:&+@%$7/%8'-AG'*D*0
@r1599
NGNGAGGTTGAGGCNNCTTNNNTGGGNGNNGGGANNGTCGANNACNAN
+
"$##!#"$$$!"$##"!"$$##$#"!""!!#!"$!!!"###$$$$!$$
@r1600
GTAGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCA
+
*'(2D'5*#"$8?GG3#/''G?"55@@'&*>=A14H/@B9;6:E-E
@r1601
GACTGTAGCTGCTGAAACGTTGCGGNTGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTT
+
,')@#F<*@<;)22E)'D+E4(<.A3A$3.47$.--0;'(C#?BC";6C()D@7"E9?8+)5:@#!G?69(:67B!'A*
@r1602
CTCCTCAGCCAGNCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATAC
+
+)!"'%(&#&!*(")#)$(+')*+'&"%"#&!'+*)"&"+)!#*(""&(!)!+(%"+&$'
@r1603
TAAGTAATGAGGTGTNAAGGACGCTTTCANTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCT
+
)4*,9A>>%,>4$7)9/5<0-54=E($77#<?&27!*A(0>+&D)1'A$B*$53-#025G9*9G<$<#489>
@r1604
TCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCANGAGGAGTCCGGT
+
!++#'&!''&&"("+!!"%"%+')!!'**&')"'%*$!&)+()%%&%!+#(!)##&#&')!!'+%*!"#()(+'(&(+$"%"'"+%%"!(((*'!'"!&+'&%)+$(*(%$+(#$%)%$(!'$"!$(%#$*
@r1605
NGNTNTNAGACAGGTTGAAACCAGCACGCGTTATCTTGGT
+
'#%&!&+$(#!)&$#*''"+*&+*!#%)!%!%#"%*!#$"
@r1606
NTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGC
+
"98.:.8:>EB;5A$H8-"%@80<B4E696A9BG7G3'F!=#0E+$;B%-?E@B"E@2=$F5:28,";*G+
@r1607
TGGCGGAGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCATGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGC
+
+,H*4>5!/G:;4"3BH)&4(C-3*#7D*9H'GA4F"+509=1)F,"@)G!(G8<(H:E;E$D/:::'8?8D-0<A!;#9!?,,0!%B7GF8<E04$0#E4FF=5*
@r1608
TACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATNGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCG
+
/;E*!1/+1?4,.C&05#%*AA:?>.1C#5&>./>&E>7<5;H=CDH&=73B73!F.%C@>:"1!;HA8'9CC31@/2$)3-7:H.?3%+:*2E<-4/1)78&#111!
@r1609
CCCGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACTGCATCCAGAAAACGGGCGTNAACCTTACGCCGGACCACCGTTCCG
+
(($1;,=H=3-.HAB@#7=4131,8'.CB&9(25@G:BE%41>$2"12H-1D:.-0%A.2;<H)&1#$4%"(7G79A/*82(#88C"D5
@r1610
NNTTCGCGANNGNGNGNNNANNGTCTNGNTNNCCANNNNCNTNNCNANNGNNTNCATNNCANTATCNTC
+
!!""#$$##!$$!#""#""$$"$$$!!$##$#!!$$"#!#$!!""$"!$!!$##$$"!!"$!"##"#!#
@r1611
AGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGANCAGCAGCCTGACGGATGCGGTGT
+
>=H*41C;.D(0)@%E3;-/+#"H&%4.%A=3<GF267H<$:C;450E16&#9A1&&$=@%*4%3?<8FC2C;)42E-72(8,%@"-4F1$+&%.*=0>@@D96(>)%/3F)!)*-:23:=6'49C+E(*BH&;.4*5#.1-/,3!2%*&"C5@
@r1612
NNNTCTNNNNGTNGCACCNCNNNNTTCCATGNNAGNTCNNAACNNGANNCCNNNNGANNNGCNNGAAGCNNTNGCGATNNCGTTNNANNNCACNNAGNGGNTNTNGCGCCCNNNNNTCNAANNNCCCTNCNNCCNNGNNTANGANANNN
+
#!!"#$""$#!#"#$"##!"!!$"#$$$!"$"#$!""!$#!"$!##$"#$#$!$!!"!!$#$!$#!""$#$$"#"!$"""#$"!#!!"$#"$#$!"!!!$#$$#"!$##$$!!#!"$$$$"#"#""!"$$##"""#$!$$##$!###""
@r1613
ACGCAAATATGCTGACGTCCTGCCACCGGAGNAACTAACGACATTTATCATGCAG
+
"'$'+'+!&$"!'#*)++#("!'(!)#%'*))%!"#*!&)#)+*&)*)*'("%($
@r1614
TCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGNNGTTGNAAGTTCCGC
+
(0,.'-:$;8>&<H/$9D/."=06EA:F(>?=2%0C3616-$+4.3!;(%;6!
@r1615
AGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCAT
+
3)74;+#4D<+=HE%8A/!%$F:3".%&H@?@+@9@")@*)&@'@B(A"2)4E1@%"'1$>?*
@r1616
ATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGCTATTGCGGCAATGCTCAATGGATGCATAGACGAGGGCAAGGCGNCGTCAGCCAAGTT
+
F.(G/G=C8(G>F>G6,$A9?;'G+3%A*:'HC(+!,=F,2BA03*6<-9.0H12:++F7))3;*A@F+:GD78FBDBB5D%7)(;=F.&141,$<;.4+14,@:,>+#"45(&F<
@r1617
GACCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCAC
+
(('$&*")($+)"%!+)!%(+%"&%%#$('+!*#!*'(!$%()%'+)%(**##%+"*
@r1618
AATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGTCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTC
+
H3<6-8<?6.&A=1/(6H(>)<D@0"#(@@B6D:>+D!=+AE+!;)=*05E06*38C:9/1=F%?7EE%&$32D-C?9F$*.@#:0H.8>;%89EF)7&7!D%0
@r1619
AGAGAATAGGGCGGTTAACNGGTTTTGCGNTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGC
+
6C84(&@B>H.C#*D/A#A)8H@7=E581%"%/',6A3D6;03,08H7(H-76/H<*+H8.<!,*64,7+!1$C6$*=%,<>
@r1620
TGNNCCCGTACTGTCANCGTGACCGATGACTAACCTTTTGATCGCCAGATAGTGGTGCTTCCGC
+
!*$+#"E<B@+;EG65.E@(;<-*0HB9(2@(2,@-D"7<=537A9FBE<A6A&/;@9:==C<3
@r1621
ACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTTTGCTCCNTTAGCCAGAGCAA
+
G%*%0A28B(7!.#G!-G8F<GC,C1GE=B#<,E=A"/C;@A#-?,"-B<F?30?D2HC<8H7>6<-G6*+#
@r1622
CGTATAACCAATTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAAT
+
DEA065A<C#<",/!!<.,>G;.5F!GB+3((C!09),63E9F%G+B8#F*F"D?8+1=>FG$5?$H9:.;03,G4&"//*3'F5$23C>8C4C+%@$+7/2':G)CB?6A0*<*"(#B(?670",-C4043/8;5%:C"
@r1623
GACGTTTTAGTTCAGAATAAAACAATTCACNGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAATCGCAACCTGAGCCATTGGTAAAACCTTC
+
1?-:G4&/1-+0B/+3-@H):B&3F696+9/4D9;@%-9;5B(4B@0AF9@+E0E/>5D16H9"A!=9C47%97#D?=E,<:6)4D$(>H"(BH1.&%>A(
@r1624
TCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTNGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGANTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTAT
+
B?E@@',07'<5<DA5.*@D20:H"!FE=1))G0=5)G=>#(:7F4<D/*":*<H:!/'+'9CH;+$&1%?#H(B!H1AH?+(*-F&)?.>?,0"=6F64)*./7?@<4'%>AED;3826*C-0:+-$C0,/-"840E>"';(53<,%G(278"=/D7E%F%%*>+@+/3'@"(BD$!@#28#5%DC0G/9D/"DC+%(BC);690C<GD$;?@9C6F2FD/'/G(:*E@H+&$$G/#A1CEB11*06!*C//HD+&H59,6(4)$"'!H$".B74=A(95#'19BE
@r1625
CCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGANTAGCTCATCTGGGCGTAATTCCGGGAAAG
+
G'0CE:096-7,/A.7@6CF'D(B!*&<4GH:8"%85*9:;1-(CB?B2E?55>')9>8@4,:#.DF88F0$$8G8
@r1626
TTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAA
+
=*(=E5%678F64;A*CC&A5A6F=G).A5G@#%(9BC3>B22>/4E&+
@r1627
TTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGAGGAACATGAAAAGCAAAATCATCA
+
A1.A#D4<=180(E>+?;*E%?4F<8;=11.'0F.F/6E,2&"/@$,/GE6G@!)9DD*97F3<>HE+EE
@r1628
GACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAAT
+
28=7+B%;/#(,+H<*52*225''-1-4,(29;("E'(;H+$EG<B5B>3>;1D-;;1<#?2#)$@
@r1629
NCTGNTTCGTGTAAAAAATATGCTTAATAGCACCATTTNTATGAGTTACCCTGAT
+
'''''+&##&((*)*('""+#(*!&")&'$&''$%)$)#(##)()&+*!)#)('*
@r1630
TCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTANATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATG
+
@(+CH"'9/27?&,,CG916'?G=)/4#&,!3F&=7$FA:H1:(&$#(&@</)55"$G(/*/*A,A62E"3<$8"=.>?<18-,:2
@r1631
GAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAG
+
,EB-5!75C<@7B681?:&7=9:52-"=7#G#A<G65F1F>3(=-D)2BA&"3D&"943E#;H*14?:>A-2(F!BCB4*?164$C@
@r1632
CATGACACAGCGACGNAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCAT
+
002;>:DDE$":#4+=#/"53#G:'2/?<CG/69FBH0A1E0G*C>6).D(&!:(7
@r1633
ATCNGNGTGCCTGAGTGTTCCCCANCACCATCGTGTTGTCCGGCAGGAAGTTCATTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGGCCACNTCGC
+
$(#%'*&%+((""#&("#)%$)'$"#'""!'"!'+!$)++)')!$%++(++!((%($"&!($$*$$$"(#$#"'+'(%'$%('%+'#*!*""%+'*)'##"*$!*$+!
@r1634
CACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCCCTGCCCATCGCTTTCATGATGGCACGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTANGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCC
+
84-D<-,!!":-=2))17"7D%3;2;5&,3G)?@#F5?,:@0@08:EA&(1,0),F#0-25!'<1<-7,"24)84FB,);6?47/>7.494:+*E$F9;17G6#"5&;-?./7$59./C($(C:!0'"*00;=>H#0;7(&$"+G"")0774:/C1H7'",'266'%#-:=<:2$>?374;H,2<G*
@r1635
NANTGNGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCNGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCA
+
("#&)&$+*#*#&)+**&+%&#($#%))++("*%(#%$"*%#$$*("*'+*$)()**"#%)%$"#)')(%*+"(#)(*"(+%!!(*$##%&))"*#$$!$&$((%$!)'%**&!'!*(#%#*!*)(*&')*'!&#$)))$%")&!*#)*(('!#$)!!%!+*!"'%$')$)$#+)(
@r1636
GNGNNNAANTNANNCGTNCNGCNTGCTCGCCCNATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCCCNTTTACCTCCCGGGATTTCATGAAGTNCCGGATCGGTGGTTTNGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATNCCTAGTACTTTGCCAACTATGACTCNCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATC
+
($'"#!(*!")*#'&#('*'*&!+!!*"#'(##*(+*"($+!!)!!"%'((#&'!!&("&"(''(&'*#!#)*'$%($##'%%*$*#%"+#"#+!"'')(!*#*(&()&'""'*%($)"%*)!&$%%'*#&!(''#!*%'!"&%#(%)'))$'(#*"'!"*$'$($+#&+)%&"$!%$#*#"*+)&$%++%+!&+#%)))!+$##''))'!""*"'"($&!"'*&'!#&(&%('%&"*#")##$(%)&)$)#***()&)*()"!(#*($*!*"#(%$$*!%+*("#))!%('"*!!+!**"%)(()&*#$%+'!+)"('%+)$+*+($)"('!()#+*+'*(!+$"(+"(+)%*""'+$#$*%"+&+!(%'%&))"%'$
@r1637
GTCCGCGTTTCCAGCNGTNGTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAATGGCATCCATCTTCGTAACATTACGACCGT
+
&$(!'))*&&(*#'$!&("%($)+)*#%*%'$!*+)'%#+&(#)&)(()&(('$%&!'"&!(+"&*')(+#(%##"($"+!&*%)$$%%)&"#""#*&&)#&#(#%
@r1638
NATGTCGTTNCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGT
+
)CB!$0;9>5G1/$<)!3'HEEE1GE=7$:8?!+G>&4C;H785FEB$B,@2%=G7*H87%:+$>@!#":E:@12:68
@r1639
NTNNCGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACANT
+
%(&!"'+'"%*)#")#(%)*('"'"""&#$)("%!)#'+**+'%#*'&*$'
@r1640
TGCTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTGGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGGTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGG
+
($2-G;F)F=%5.+.:D@3H/-$52&-D(3%?34+5BE1.H?3G$7@1&D#-$'0>@C89G7%0C6819%2/5.+B0?.HC/H1)$6*F&-BE>*B6<'""':H6F!6"%;$$(F$>DE#!&G0F%5<2+,>GF60?BH!(9**>G9+,B:"C<0;8H!4*0-)68(*!+?/-<=*H7C0E35?.H::AA@=.'3D*6/2--2&GFE'"..,3-9&H88%E9H9443%+39D30@H!CC@H32*$HH:G==;)-F>F.B93"
@r1641
ATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAA
+
-%22.0,7!0D'@;7B/H/E><$;$33B=(),+-*),:G=,!29G6=,483C::0$)85B+?AG39%&42BC!:*C(5,8'</*,4<:)@%4.-'C.#='8A@&?7D)27,G'?F6%.+++0&>E7@3BG3AE+(0C+#:GC,(-
@r1642
TGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGNACTGGTTAA
+
F51'1;4,8..+D1/870&*7;/?+$#FG(3#&@@2:5,C3!F+<E=DFF@22'5F0BG630D<C&/)*>A(H@F">&930FE>699B:$H?<H'/H:3'&"'-C9/4F+7?@F"@!C.&%9%>DB)=E9H>G<%E04(AB@23#/96+-:=CG%$E8?C!+A=>,@#4(*CDA1/:?>+;()D'@8:>@83>?GA
@r1643
TCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTC
+
=566D$#,/"!G)-/CA57E?#*%?!<8GDEH*(10FF+-(6DH(8=*!'B%$A-8A'E7.'!30*%@F>9=0)633E7E8849EEF>*17"27#+>&7).<G*1E>'$<1D73E#G;:9:/G!!89A8!B,A30./'+.=&?F6'CHC05"5A"6H>FH/9:((8.7)')%?78%/<#9!;16<GB>#A=
@r1644
GATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTA
+
4>=5<?0;9F;6AE<,$5/H)8"=AE3)-!G6,170F0:,A15,CE90&!8?03)?*;;&;)@6(E.1330
@r1645
TCGAACTATAACCCGCAGACGCGGCAATNCAGCGGTATCTGGGACGGAACGTTTAAAC
+
:1D-DH7?.>.C",A;):*,F1HHE(>#3D*8:>F%*H<(.D1><=2%'-B%9=B:@F
@r1646
AANAANNGGCATATCGAGTCAAGAATCCCAAAGGGATGTTTTCGATCG
+
)$#%*$%)!%"*+'*'*%+&""(&)'(&&!%"()%!&('#"#$'#*%+
@r1647
NNTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTNGATTATTGATTTCTACCATCTTCTACTCC
+
(+<AE12$.A603>1@5$F:,$&=909>(0*,1F02<#":!.#B4+HH%+B<%'@1%C560@#76"0+1A@C";6)E>96$!18$E$?A6+24%B>B15:
@r1648
AGTTCNGGCTGTCGCNGGTATTGTTNGGGTTGCTGATGCGCTT
+
+#+&"'!'%*%!$%+$#"$+$)$$#''%++*)'&*+!!"+$)"
@r1649
CNNGCATGGCCNANGTGCNGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGNCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACACATCCTCACGATAATATCCGGGT
+
*&"!)*#&)('$'!'#)")**+!$$(($)!**#*#($&#)'*"'+*#)"&(*"%()$#*!#'%$$%(#'*+")&%!(!'#&(*%'#+%('(!$+"$!&%%#*""$(%($#)"&#!%!)#''&&$+"%$)"+"'*$&"*+()$&$*'**)%#"&(!"&("+&&"#&+'*%&*"&$$'+!#"&%%%+(!#!")!(+&&)''$&!$$%$"'$%")%")*(!*"%*)"))+"((%*$*+$%#!+($#&#*"+%
@r1650
NCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGNCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCATCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCNGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCNATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGAT
+
$DB3#/%+A"'1&3&,3$1&)%#/-?7B4<'&,0B!2119F"$F=H.</GE6<?D-B/;$A'.F=(9'FF8?:<*)6)G8BG&<323@G5(F9DB)6(,?2%-!1B%4@@:$!,/='?G.:"C2G-.7F5+$/%:5/521;C8/?;!%H@,AC8)%GG!"0%=.7!'"D5-46*01E?.H&G5G&B...3?'">
@r1651
TGAAGATGCAGACTGGACTGCGACCGGGCAGGGGCAGAAATCTGCCGTAGATACCAGCTTCACGCTGGCG
+
971G=(FC32$4#(79.$$+:%,31B%C0,&:;EG#7*#5A:?=+!A3C/25HA)1."&C('>''H#<$"
@r1652
AACCAGAAGACCTGCCCGTGCNATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGT
+
C=3;C#88=E%A.D9,C@&BA/E!+8E;$-(."764(E5&<7@C&$C9?$9*?AC)/>H6&+A3:A1+G,B9!9996#E3-6D%H)E'E5'1=@(;#;A$0*0+4@"+D<!/?9%A$?C<%*=;39FCD4#434B83?7>
@r1653
CCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGC
+
=B5!#.%2+C-#C-CAC,=D520C+@187(!-3!;AED/.,4/B$!0$"+((!,HG>*4%F!B4+1&8/<68+0HD?(@'C<HA4&,A'6/H4G)AB1BD-02B)'.!2=DAC+$@'?D#)4>8HE+
@r1654
CTGNGATNTCGTNACNAACANCAGNAGAACGGAGCGCCTCTGCCGCGGCAGACGTAN
+
'#)#"$!"%)"*!"!*'#&&"*("&#*+&!#)#%#$(&*$$)#(#(%%'!""!+*("
@r1655
TTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGT
+
9+%.3$='C%"@',6%&AG9D1;/("CBA=@1$%?2>-#C*)29D+59)86$GG/(7"G,D$1C$F+=G'!34=#(>;-C15C
@r1656
AGCAGTAAGGGGCATACCCCGCGCGAAGCGNAGGACAACCTGAAGTCCACGCAG
+
).80+E<@!.@E'.;:F(B-*4EHD'!&9*>EDC154>=3(+&"2)1/473-57
@r1657
GCTGCCCATCGCATTCATGATGGCCCGATGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCG
+
/A*5G&(6?90@A'2%-(%5(&0HH#%G7,E'%FD";56&!.)(A@FE/?9F@*,5=3%HAE4H727
@r1658
AANAAGGATTATGAAGCGACGNTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGNAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGNTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGC
+
&)*)++)(!!'!''")('$!#*'+!$$'%&%+!")#()$"(*%"&"&))!''%($!*'#!$!')($*$#"$#&"("&&"$&))&#+$(#$#+!!('($'$+)$+"(*+&$($)!*))+(+$*&#+$#%#&'+("($**(!(&+$#%!"*&%+#&**(%+*''#
@r1659
GCNGTAGAAACAGACGTAGAATTTNATACGTTAGCCGCATCCCTT
+
"'!+$%%''(%$##'!*$$&%&*+('$!#$&%"&(*$"!+*"'$)
@r1660
GCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTA
+
+6@5#?H3,0(D&)?<*D!-'B@*@41)@%69?#22*F,B)//3EB8&=!5,&A
@r1661
ATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTT
+
&&+$%%)##&#($%(#*%+#)'&*$(+&"+%+!!$')&+#&*!#%&"&()(!++%+%"+#%*%"()!&(&%%"&#*!*&'!!!*"(!'!%*%*$'%&"+'&!&&"#()#)%&'%!!*%
@r1662
TACAGCGTATGGGANCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGNGTGAGTATCCGTG
+
<;3/7'>?8E77=+>GDC0?1?G%):7G8-3:6#=#(+88%&1).22,:!A54F7A'"81(F-((&#
@r1663
ATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAAT
+
E6??"G</9/25(/9=B16<F!,)<G@484C++'C0H:$>D#?;?;(FF8(E3&%3D2@.E#?6+;F@7$)458"?18E
@r1664
GGAACCTGNCGCCGCGCCCGTTTAATNTCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACNCTGAAATCATCGA
+
##$(%((*&+"*!#%*+"&(*&)!$"#')+(%($%%)+$(+$('"(**##(!%!*)!$((+"*%))!%&"")$$"+'+*)&(%*!&))'%&&!!&#&"!$&"&%*'!&!#&*
@r1665
GATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGG
+
.+!.(D5//H7+F/.'!7*8C:F,%"8%"+E0);H?53:4E>*B,GBF#C/$#+C"6C'(?:6==D5$(&/+!B)4?HE4
@r1666
TTAATATCTTCAACTGAAGCTTTACAGCGATTTATCTTCTGAACCNGACTCTTGTCATTT
+
D=?@9?"@'391$#=EB3):;@H10:7FE:CF4"=A,&B=C-B=H,#A3@A>04D'$;0.
@r1667
CTTAGGGGCAACNGATATTGAAGGGGAGCTTTTTGACTCATTGGATATNGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTANCTNAAAAAGGCC
+
;:'<A,).2,9*21H*H#82(614E<C@.:C;2;(+/91"6!)<A$(>8HHA+$#<)>E!F'FF!+A@+6(ED<46!7%<6:HC53=-2*.%H'5=)+A</F;<>5&F(.7C=;1%21<?29"C$-69CB8,#G?#5D"->D.=/@3B*$"$',#A=>65A+,"00EB,#/%,G3F>D3E6-'9.->##C3)%9HF8
@r1668
CACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCCGGTCTCCTTTATC
+
*1.-H!>&H-@"(8*)"G91*<3/*0'40F3$58:)72!1,2*%G9'HC-2A0!&.<7$B!!5+F-A#$??$59@*/EGH):
@r1669
CCAAATGAAGCCACNGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGTCAAAAAATATATTTAT
+
+:C3<C'1G&.(57'(>//54+='21C6"<H04B"!11F2#,7:-)B-9+./HBB2+AB6.'-,:E=.
@r1670
GAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAG
+
(F/,8%3C3.G?"'/%#.#*5/F)!H8-A%D9&F3:-4H&F:B!BC&03
@r1671
CCTNGGCNACNTNGCGCTGACGCATCTGCATGTCAGTAATTNCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAACGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACNATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCNGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTAATGCTCGAACTGACCA
+
$(!"#(&(%('**+!*+"($''%+&+%)+#"+$#*'&%$$)*'(&")"&+'!(+()$"!(((*'&*$'##()&$++(!"(#"%*$&*"!&()&(&'$!(!(&$$$"&!&%%"("%%%"*($*#*'!#&('!+"(*++&&*+%*'+!%+'$!"!$)(+'&+*#(%&$#)'+**)#+("(!+#%"'#"")%)&'!")!&&$'#"%*&*"))**)$#(+++#$("&(!)&"")")'*%)&(%(&*()!"!!''+"$&*%($"$'+(!))#%
@r1672
AACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTNACGATAACGTAAGGAATTATTACTATGTAANCACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGC
+
*"F5H4/)17E+&@G(;??0/-()5C6"04%0D*?=D,8"')@/:5*FF2)%C"8"EH1CD#.<1CCE:8+@,)27"24H4B=2H,E";+&(!BFDHDD%4&D7;2;H$(7-2%>B.&D>=%424HGC:=A
@r1673
GTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCG
+
H87F:?E%.6'04-=25EB:<*-+'6/7CDA7A#C3)/A""3133..;(A'9'77H30H2=-3
@r1674
TGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAANCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGNTGTCCTGGCATGCCCAGCGGAACAGNACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTGNGTTTTCTGGCANATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGT
+
FH4"(9,"?F90AG*;(7187C1&41#.30$C)CC0@@=E6-;B!*#;)E&<?A1!&5=5B'=/H!(-D214F%8?>HG04A.+.'#5*=5G'>-#.A&(&DA4C&G#$B&:1;*%6@2994-=F45$')7C-.AEH59GD?C$"4%#$D6)$95*!<@;&"1AG*H55D;<1CD),+#/?F+@9'*;%1F#>9#&@$>1EH2B1;9:8D+."05,&D?=E.89)$,>!#+<#-F,:753;*50C3107*57ABH3;2<1,'0.(+)&D=((:F%$0A9,2?->7E&7!$B#?/(E*+H<1%?12)DFH'>37%0A46$4)"@G>$;>(23>D)"&3+>A$AF,<4,#26.)(D,E0>"A>+0">2=!.!*1/+73>9?F0'AH$$/9E4&&A=%?F97!0,A/?2G+-(=9E$<G-,=G%+5?91H-/$>(?&G$D.,=AC;,'%?$;E00(G111.C%3:>?2DG3$&
@r1675
GCTGGCGTGGTCGGAGGGAACTGATNACGGACGTCAGAAAANCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATT
+
9&5!&1-<<)5"D4+&#698,7DD7**&&:A=!#*6'@$1A&-.+%G3B@(32$%%C#++3=--")>3@+C;-%81;.<7F:,,?5=E.16,
@r1676
NTGCTAGATGCTGATATATTTTANAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTT
+
*&@D"H94=,.D@-%,D?!/$+3=&9B@);A"'GE=?67E%!0;:<FD/6>*4<G::<+F+D=8CB9C<;:
@r1677
ACCATGATTCANTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCANGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAG
+
*&5&B<1,-4$=?G%+.(F4E9@%=@>')22H,7(,0-<#F)#+**#4.9B!<=!<&"0&1,:7./:>36@26+'%,/&29*(D@E5*2#='>C!*?/B4?!FD?>7/#*46@?8:79#>H:.7)D3',8;,)DD&%.;":+;0,-5)DE#,)"E;86!<,>,F>,(=GGGGC5/HH<CG(1*G753"+,)<A%*4%?;28AD%-2;:A%89F>FA4;B6)")<H=9:
@r1678
NCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTA
+
!9"/4H:0$G+'2E,'95*2>$(C+83()CF!F(3,:#94"4)-8:6D,7<!9<,$.::0"D18=89**'2!.6,82&(A""07D/767C#))E:,D-8!E9
@r1679
ATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGA
+
22%;B*,%(>)7F#*%FH?G!#A>02@50G9+@&+B+$5(.D2B,-.-53$4=9;G5:!@,9H*$2G!.@H>1)90F.399:8(%FA9A<6<04;68*H@<'<,&5B%H735D&&#F-&G=41B<H<>;G>%>./(G=08-2)2;B4"EC27E-9187
@r1680
GATGATNANTNATNGGGAGTNCCCTCCTTTNTGNNTGTNGAAGGCGACACCATTGGTTTTNCCAGAACTGTTTTCGGGCCGCCCCCATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAG
+
&#)%($!&&""'#'#)('##&(*!)!"%'&%'!$%"*(!"'&#(+'*(**$*(!(+&*)%%&&'"%$%*)"%)'%*%*"&*#(+&**!"+$)+"+&'*"'!%%%'&%()%##))##")$&$)'%*((+*("++($%+#&"&)*$*$'&(!'"+)($+"&#!!%"#(+
@r1681
NTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATA
+
$HD*;:H?,6:E#).-4=<C%&E;.=12&)79&&@G22#43B?+BD+/%<1#A>.HD&%!6H&C/9:5*7/0%%+?2$?
@r1682
CGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCNGCTCAG
+
BA:0/"#%</H!*3)C;!7<6F<B6-"/"*D9//6>()08D+%E:4#->#-AC6D8'$"A272'
@r1683
CAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAAC
+
*=4;($6G@,-:B58#=@4A<+"6C/10C,5)/F"&9>4"-
@r1684
TTATGCGTTGTTCCATACAACCTCCTTTGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTGGCTTATCCCAGGAATCGGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAANGGCATCAATGCATTNAATGCTTATAANGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTACAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGNGTACCCTGTTTTTTCTCATGTTCAGGCAGGGA
+
/C<3&D>):26>+*G&@0.4#B1:/&<$""23%!-;:<)9B=*H+?@@%14*75+C.4B#CABE*@&A5#0@D=*A.)!.%!:8<?"60;;@@3.!>;C%7!7@!'?:"H.*>%B348F:725CG'#,C'(8FC:FEE<1>6&5@!B>2A9B#%C@.26""C6=,,+0)-<&5<;;&%>5$AD2CGB''7@8GG0?,E"-"+:/<0A3.G@H/D=H?93>E<&57)"G339/F>+5=,,D7/AF25-6A-$,#'B60)1:<)9;?F%2:?5!G!>=/",=,:;B<*/0;0F!:+=H%H6<*<!G*C>E(61%(:%">)A*?#8%%H/<8&,H/A)B:&58G(D=F$4G'G="8-G*2*=?7>B1)=$D%%'&%/3<B(4BC:H9)H85-C'1!07E:5G/'1%<;7,'@95-&*28*1*$'F'G8)5.2"/@6/B)F+#*8?&7-D/"<-00@*:1
@r1685
CACTGTACCNGCTTCCTTNTCATCTGGCGGGGNTTGAGATGCCGGACTTTCATCGTGNGGATGACTGGTGGCGTAACGGCCAAAATCTCTATCTGGATAATCTGGAGGCGACGG
+
'&&%#%!'%"&&&*!')(#%+(#)&#$"($(#+)'&)'#&)'&!*'*%%$('+&&*++()&)'%#"'#)&'&"(*&&"(&**'*!!(!*#&*+(*"#()+#&#!'&"$('!+((
@r1686
GTTNGCGNANGCGCANGACCAGNTCANCGCCNTATTCTCTCGNTGAATCGCAAACCGAAATCAC
+
&%(!##&'%!%!)$)!&'*&"(%%$)#*))%!#+'!'%(!!((*&!)(***#*)"&#+&"#+'!
@r1687
AGGGTGTGGAAATCACGCTGATTTACAGCGGCACCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTC
+
8+)>>$%203/H+/7C771$767221A%@/21:FA@6-ADA;*7&BD#>1+'4E-H-=93E(C*8/A7$-+G>/(.:B@-1$%$<.26$#"7F!;H;A)99.$*1;;)/@E@04.9=4B3.1:#&1+&>?:H+:'943C
@r1688
GNTCTNNNCCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGCAGGTAATGGCG
+
((*(($!#!(&("+!$&("(')%#+"((+'#(&!''&*#(*"&%!"#"%(!))+%$"*
@r1689
NCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTNACAG
+
$%+<D>>;9@C;@):./-9'H!?'!;6F:22@(=;30%F3'(E("(!4A);+(A.B0?-&<G&A)=%&7:;)$=-;0HF036-#E0,<7/$'=B5.#5D),$38
@r1690
GATATCGTTCCGTCTGGCTACGTCCTGAAGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTNCCT
+
:!2%9$F>'*:<B"F4528.!#3<=,4+*+."?8@."<1-5%+H/5GF7"E<7=)3%:A4:002'"5%/,(0AAH5:"7',($:4D!3:D93=68&97$
@r1691
GCAGTAGACGAAATCGAATCNAACCATAACCGCCATCGCTGGANTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTANCNACAGAAACTCAAAGACCTGCGAAATAG
+
+@14008745CF-7!8(=F)A<AEAC:A7:D6="@A&3473$.)??;766@D"%(;6&')"#+;%73B5G&=%,#&<F.EH46.EH=9&!1@%A3(('9F73$0346
@r1692
CGGGTTATTCTTNTTCTCTGGTCAAATTATATAGTTGGAAAACAA
+
5#(B46"0A!C8%H=D?7/4>2198(1C)*)6)=6#,<1'"A"@2
@r1693
NTNCGTNNCTGCGCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACG
+
&)!&*&*#(")$##'+!'&+"&#&%**(+)%""()'&'#%$(*%$!"$++!!+!'')#")##$&&#)$)%(!%$("#"'(%!!&!''*&*!&!+%$+!!&&(+&#+%%'$*
@r1694
ATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGNTTCCCAGCCAGCGTTGCGAGT
+
15&$<5885/?:E3(*+,"#?>!(271A@&&,&&)C,7?4=)7<0F(,8!'%/(!8;4D>>96=:5A8B
@r1695
NTNACTNAACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTTTGCGGTTNGTAGTATATTGTAAAGCTGAGTATTGGTTTANTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACAGCCAATTGCTTTTAAGACTGAACNCATGAAATATAGTTATTCGTCATGTTTTGAGTCT
+
#!%*('!!(&$(+'()+'"#&%*+$&)*%(#!#&%+#!!!#%%+)%"#(+$&')$*"%!)"*)&(&'%'$&'%'*)&&&$"%!#"%'"$!")'))!+&+*"!'"(%)'%#$+%$&'+%'#")%)#%*!&!+*!+'!%'(%!')'"$$&#"%!*+%&%"(*+$')#'("#&(+++*("%+'*$*""*&+)%%*(*)"!(%)*&&$%&&#+(($'&'&"+!()("$)$**'*'(+%!')*)%)')%($)*'+$*!$$(%'%&
@r1696
NTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCAACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAA
+
!C%1.C+>:>(*")>*6GGH%;%)A5H:?/5?H)#E>H->EG</.DF?EE6G!0<#F%GGB-@/;+3%;0D:+G2=</!80!A=%%-E57<(*7#,&7%;49@8A+CB-"/>)/+"E1D'20GG$5:0/"**@=/+<C'4$0@B1H+:H:?%=(<.3"E7@E0&DH;D?,"0)9"1<=G(;:<<F@>%<1&:DH909017-<?8&22F<7F-D$!<.C36"*H$%#:24-
@r1697
ATCAATTGTTATNTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTG
+
(G6G'@*366D7A3==%>.+3&1>9"@*D=0+E&@4H():$<%$EH"09--7%='H7"!H09=/;)(C(#BA4F<#@(%;;
@r1698
CGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCC
+
9(G;-H;E!0:DD4&C9>A1C>%7E#G3"H,2GG%>>-$'/*4"H;-8/,#-,3@-H'8+-%$
@r1699
GTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATTATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGG
+
>0?6-8%6#A02:=2@&E:4B!,!.63.7,*46-BE"@B)8$E;(!E!2&=>3=>7=+G/1G#(24<D84@$<<8!!0>;.076.1GA4?;@)G+H:".<"%(>7
@r1700
TACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGNCGGTTAACTGGNTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAACCTGTTTNTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCNTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGNACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAA
+
+!@"F63>+D!+EA.9B0>"AA6H9;G/#>>*-.)8;9H6B3!,37.=*6>9/;2<1%%G?C<7*6+*.8E@9#)82E5>:.80D7845>B-'>46!?(+5?"0@:%1-C7-E*5%8%<#1<:;88A/G;,5-F1H",<#?<;8#@<#):@',;5HG,5;./)"532&7A,>78AC2<7=!B13?G7<(B#293%+4%/2+8(?)58=.(>-<4,9,&7G57<''.A<00'*FF-@4,B/E$>H$A"/?.1/E/=%?4@"/0)1D>()9@;B.%/FG@0=C&*G5A4E0:2H#)0D:0E=&.8(."A#0G7#3%7:E(6'@.#5##7H>-'!>+?:!B<<-9">ED,!;10264C4:8C8H729:;/="C/>=F1*
@r1701
GGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAA
+
+9#3D/4(5%:07,A04%!>4#AF3#(?/0#+.":3D3:<!
@r1702
TTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACT
+
+$(%*'$!(%&+!%#&"%&!("%!+%)$*()(&+!*'()+
@r1703
CTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTANCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTA
+
(+&0,7C.$,"4?H)908E1B2*:$H)07!'G;CE-63/&9,!7G7>7:19'A,:5D#03%HFGACD4">,,/CE6.?1?7)$)-2,$50/&6F!907?!+"#>47.H>)"";6BHEG=7"D"G1@35**B<5835,@=A.5G2(3'F%#.52&*F#)7D/CE4%">,=!@5&25+20+>H1
@r1704
CCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGNA
+
@(7F+>&F')#).7)2H!H'>680<595.!.?'26A;,%1D",300:4D&A!2G)"*6$>!=$B)<E8C<&BEA&)";0"D0E#BG'-/,4G
@r1705
NNNGTTTTTNCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGA
+
##*#+*'("#"*#*+)!)$(*!&%'#'"%*%**$(!(&"(*)$+'!$$"$&(&#+%)*$"*#"(!(#!)$))&)!#'''+&!$#()))""'$#))($"((&*#$(+&&'*+&($!*(!+!+#$##%+*($$!+*'%'&("'#*+!'%!#*#+$"('%!&&'%&'(&(%"#("&(%*&&&(+)'*&#
@r1706
CCGNCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGTGTCAGCTCAATCCTNGACGGTGCTGCCGGTGCGGCAANCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGAC
+
C/9!0#C#A#>@'9!.A=DC7'?D,"8C=.13D-+0*@D.5%H./7>15:=17E5,;3837DB1D>/7:E"=!HD62F;151+>+)D:7'?H921.(G0H*!G/!?BG<H$2.&(6='#;&"$>1C2*<;;F@1'?0@"=*D61'2B54*7
@r1707
NGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCC
+
)&A!"!(90B$"!<H@CG3;D';>A#+A#!8*(/CD7B7:8!>*0%FD/B;)FC("EH%=**)0.&%:6@$8#!.=%&AE<4@E,1656'6,G>(%.HE::4(-H,1)*+F.#)2%?!H&@'!4,;AE#+-$">:?>9H*+%<7F6D14)#B->5%G37G8G#!2
@r1708
NGTTTAGTAATCAGATTTGTTCGTGACCGATATGCNCGGGCAAAACGGCAGGAGGNTGTTAGCGCGACCTCC
+
$)*'(*+'*%*#+%+*)&%'"(*)"(#!!+!*)&$+**+*&)"%!(+&!&+"%!'&)*'"#)%$)%!"%*("
@r1709
GAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCC
+
>%)65%1#@(6%5/7F5?63C0%C@>0@<.,CE#:<,1@;>A&D
@r1710
GTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCG
+
'+3+E6*'2D3A'08##FF.7FHH@79!1))AH>9H.)6D?,/+%;!14E65DAB(H4.#(@$H9@-G((:!9C<</6@7<1
@r1711
CGATGTTATGCATATGCATTTNATCGGCCGAACAACGGTGAA
+
6&"%&)83"2"8D<-!2"05!.&+B3H9#;A='5H5,9>7,0
@r1712
ACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCC
+
H8,9$A<6!B9C".C;$.BF0%:9>;4>>5@@B2=-)1&?,3F4)4(5B<E>2$$35",6?F!7=7/$*3:8)+5
@r1713
GTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGANATGCTGCGCTTGCTGGCATCCTTNA
+
AB)..#7:@+4,C*6*:B>73GAH+3?;*;@7/CAD$*>54A;9GG2/(+$2;)?=84#,4!(/%+61:(7*4$,4@;8FHBA
@r1714
TCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAGAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCT
+
B%<+2C5##F-E:;B%?AF6D454%9,'*7:)5+:6.3'!&G>;@F9104/>040'?"#8$0-F*)#))9G?%6:39@A506H'$3164(8@,:9*>26.,;E8>0(DB91(&6;
@r1715
TCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCA
+
22;!FG-9.29)(107;4#B0G?-2E)-;B/H).>=;($A*@*@(>+!<-G>)!-$FB?$H1C1A,-(%D=H1G;B
@r1716
ATATAGNACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTNCCTGTCTTTTAACNACATCAGGCTCGGTGGTTTTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACTGTTTGATGAGTNT
+
&$'*)!&)'$(*+)%'&)(+#$&!)#)"")$"(!)'**+(!()$+&('%(*!+"&$("+#'!)'%+!("'&&%)$&((%+&')+))!)(#)'#))%&&'!+)""&$&*#&%)&'+$&%"(''"'+()"#$!"(&(+)
@r1717
GGCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGNTCG
+
)(1E3;*>=(?@(E+2*>.@4C,*+3.".E1G1%G615<.!9E=
@r1718
NTCTTCATAATTCAATCCATTTACNATGTTATTTTCTGAGGGGAGTGAANATTCCCCTAATTCGATG
+
$+.+5:/7'H1%$)*6.44?$B(=)/BE>82G"97F0#9$6?$DHFG@&9&*95GD61$@G88:60(
@r1719
AAAATAAAGGGAAAGAGAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGC
+
02/?DD#G%90$G>8/103:D$@:6<A2"&2'&7D716.@7.C+:D-/=+C<965:**BB5
@r1720
NATNAAAAACGGACTACATAATACTGTAAAACACAACATATCCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGANTTTTGTCTTCTTGCGCTAATTGTTTGTCATTAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAA
+
!!')#+$*)$'""(!"))('$*!'%((%&#)&'#%$#&+''&%"+('&%("'+!+)%(+#*"$((#'+$#!%#$*$(%*&"!)"(!*((*+%&#)&$*%$"&%#!"&%!(''&%)#($!!$(+%"#*'*(#%**'&*'%")(("%&+!)%+!%'&'+"#++#+)'!'!)'$'()!!+$$""'&!""''()#*&)"+$!'&("'#)+'!(&+"%!'!)+%'#
@r1721
NGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGC
+
"H9/6(=$1D%&?:D8#G0720%-(;F-78:8?7'&&=>7';!G.AAFH:9=D++25
@r1722
ATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAG
+
-%;,1F,**>$8)5,0?)4?+3+"E$37A*@24GAH)=..$)41/7#79!0.
@r1723
CCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCNCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGANCAGCGTGCCGGACACCGGCAGCACGGCNATGNCGTTCATGACCTGATAACTGCGGGCCTNTCGT
+
:5C1/GD)%5,&##3?@4@26@8+?6+F&'/.%BDAH:G=<"7&EA(2!/'0*/<;0<G.-%4(#244G'A@*"7-'4F772?(;:A3(H=A;(+9)B&H(,=@#8A)?(&8:&>)*D/(47B*$DE,9F*122:&CF4790@!D'(0):E&194=2<,70=DDD
@r1724
AGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGAGGCTGGCCGGTGCGATCACCCAGCCGATGGTGGGGGCCACCTCGCTG
+
2A>'48)7&F:89*;.C<'H%G8;F;FA/(,)>2C8D7#!..$#3*8)@B#/***$1=5#)"@)6>7:6#E,#>D9+3HF<<9B%5B+@'>#4&''9%
@r1725
CCGTTAACAGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGGAGTCGGCGTCACAGGTTGCCCGTGAGACA
+
.)-#385HF+%,C0F+0A(6105.9.C8G)EF0@)<'%=3*9):86A4##D0<EF78@:4'4-D67..;?<C3.+EH=)E8%B,A0BG1588=<*C@;8E/(@>#<68F!=G%.5%2>ADA6/(:+&9F>D)A5,B@*"B$H=#;E.?/'@1)H:?/DHA">!GBD%6(D&0#'G
@r1726
GGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGC
+
B07!&@-/25*)7"8"6+*C!95,;:>2,+&:&5'-6@G.:/E8-'8E'?<D?:&=6'.5B+;@,:8*$02#E%G
@r1727
CCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGG
+
*8F0%=2:%)E.=?-*!$;D=?,")/=.3/B,-30HGA+)$6CF>%(3$D?
@r1728
NNNNANNTNNTGCTTATNNACTANNNNTNTGTCNTTNGNNNCNNNGAAANTTGCTTNNNNGNTNNNTNTCGCTNNNACNANCGCCTGNNCNGNGGTCTNTNAANGNNNNCGNN
+
$!""#"#"!$!#$#"$$"!#!$$!""#$#!$!##$$!##!!$!!!$$$#"!""##!#!"!#"#!#"#$"#!!!"!#$$###!#$###$!$!#$$!$$"!!##$#$#!#""!"#
@r1729
CAGGAGCTGGACNTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCANGTCAGTAACGTCAGCCTGCGAAGCAGTGG
+
:.@4+>-"*-8!3?$6G)<F$$*16"*B&4C.CG(;F!3/0055$/:1A/)#/"!4619=)FA5,%E%??!:/'-B93*)$9)-2;%4H&1)2>6>B:3D+G">F;G3)D%'4;F6C.7->(-9F5643<9%'>&,><")3C/8*:3C.3
@r1730
TCATGGACTCCTCCACNAAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACNAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGTACTCACGCGCCGGA
+
%79;>&1!F"*:+99)1>/-9984G.14#H%-+*%7'6-9BE3/!@C-,397/&>(B0H:)"G:064(4@D#@5;/%<=614D?'-7+E&#;+%!,+#*A)C:C@=H1&'+'-5.5<,13&B*+*/'D$%%.1
@r1731
TACGCGTCAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTATCCAGACGGAACGATATCTGATGGCCACGGGATCGGCACACCTGCCGGAAAGGCCGAATTCT
+
G&E">2852,.$%46?8(E+2$&D/>F'C+2-?H%#4A&C=@0-,*0,(4:3#CA%H7-*5GHA*@9%<0H#.,=<,)"?:3#$/$@@8F*A.+'40G:)#+):<68%+*630$<9(8C#?E4*
@r1732
NCTGACGGATATCACCACGATCAATCATAGATAAAGCGCCACGCCCCTTAATCAGNTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTCCTTG
+
)A<F:)#BF4(B*H;F'E,2>FC6C"9G.5'3G**G6*G40(':C*4*@4D';24)63H05/"-0**E)+31%GH>).:<%5C$G2#6F#((C/%@E!"*='?C$8+D&=<H/
@r1733
CGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATA
+
:G=E*:+?$@%%689*(#1B,B,A/;8#"&%?)<%&E!?#8F6?2@*8.(!6F)=H$@693*7G?0-&/7.*?(8;/)?5@=;4#7<9@*,%%BAG!9*:@#?
@r1734
TGATTGANTACTTCANNGTANGACCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAG
+
$&(''(#$#!((!($!!%%()''*'+&)*($'((*$"!&%+#("%%&*""%&+%(('"%+()((!"+")''#)*%%%)&(#&**!)$#'+!&""%)&#++!$##)%%#"&"!'&%'&&')%(("!('#"(**'!+##%%&*
@r1735
CAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTNCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATC
+
+'&"+*%*!")!+%!#&"')&('!&%!+"$(!!+*&$(%""%+#$#''!'$)"+(')"&%"!%!!!!+))"+#$)%'&))$'"*#'$$#'$"+#%&'*!!''&"%))*&'(&##()+%"*%%$''
@r1736
ATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCAT
+
:%=!-3$C716B101#@H6*"(DA>5)D";B,'8/$),GC9>2@03!#2,4532'$<@($<)';:791>B(+G$B%
@r1737
CGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATG
+
%C='E>=('38D53."7<0!)C?-'&+?>A/"'8@@@*11%',)F#@.,C
@r1738
NCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGNGGCAGC
+
&:<:<C(=#A9&B@:1-=96>?$0+#:;(>=6/8C.=(;E=4,C:.>*(1,ED550DC8,@+3=>@;7$B<78;-='*)+B!>'6D.-5CD&%<A'
@r1739
GCGAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCA
+
:((5./@D?*C"9F(#>$7E>:7-6@(E:!?6(6=BB>>@"&8*/9>&6(<B4<=624G$
@r1740
GCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTNTATTGTANAGCTGAGTATTGGTTNANTTGGCGATTATTATCTTNAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAG
+
'*5-)(A06079=!(=8CG5#+'+D'AC/0/FFG0H07B*&?*&?H6F/?70F0)H>G0:8",:'.-G7?157#!1B.H!=,,=C;H(.)$13,:GG@BE)E8%-B??'/,1/A8AH%69=D?/:)/
@r1741
AATGAGGTCATCACGGGATCCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGA
+
H>EG2>A1++!9;#0>7F838?2"F#GF&%#;=$15EFF2=E+<E2@'.8:H0A4C'$'(/2H1?H8251%)EF"58=6G-+'4FA+>&95&05*&5&8#=2BE48?/B!H'#0!%DA;6"G4@,%??=C):"11!A4,(++-7":3&:E?2)#/8
@r1742
TNGNNATATAAANAATCCNGAAACNGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATTGCATTTTGCAGACCTCCCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTG
+
&((!&(*(#*'+###%'*%+*"&%%*+"%&$+'+)+%(#)&"+!$&)!#$%!+)!((#($"(!$!+('"$%#)#%!$))+'$''#!#'+''!$+!&)$)*)$*%$"%)$('!)#)&$*&'(##**%$+)!%$(&
@r1743
CGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTACCGAGAT
+
0D369GD.2"@2/#')G7/8*#>/G+E.+9,,=)G7-FFA6'3<H>4?@-<!("%,;5(%7"
@r1744
CGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTNGTTGGCGATCTGCACNGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGNT
+
:8'C6=8F?-7?.37<C0?>&#3+7'#9@!/?C#-!"57.GG6)5&G6>!3D0/7<@>?5+H8&0H,#DHCE'HH'''&>+7+A";/9-;D&*(+C0)(>:,8@7$91.?:9H!3+*,>;>&@",254!0B$5&)#7744(E1/#@$'B,95<<"010&B$@$9-5(6:1F#;5'10?"&2$).;A(4,#@HH&$:<#F,1*
@r1745
CGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGNCTGCATCC
+
F@F?##<757%568FBA2&A1:1*&?<*)4E1<0@A%5CG62F:9(=E7?-%2AA?$?/H+?F'2#.7)9GA@68>')7,2!A
@r1746
TCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCTCAACTCTANTTTTAATACAT
+
:22""'&.;F?-1&?@G0G#='F55>='F#650'&"H@++'$<"9;>'<:7:F9<
@r1747
CCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGT
+
>>7@2@-<'"EH0@B5:<1,).&-D419E3#!.G?1$0?@-23161+0$A?;G*'?<=C'A#1*386#6H,368&099?9)<E1.G=%!;
@r1748
CGGAAGACGTTCACGCCGAATCCGCTCAATATTTTGTTTAAACGTC
+
>9&AG<3.4<F%GH<<9>7&'8&1G3509&)%D$G#%>E$10%$19
@r1749
TTTACAATATACTACTAACNGCAGAACGTTATNTCATACGACGTTTC
+
A2#C%8/,#0:*A0>B5!*<E-&;7E4.7.(-?.=H5>+?2F19:+2
@r1750
CATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAANCGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGG
+
G*FD:$6(6!)2!7-,1+?!7$%?F?+)D=4-&D$.<E5!G@1>E((@#5+H#F/D:<.()+1="8)4F=$+)6<*(E/D.#/,-)-9+H0<3EE$@'$3?,:H?H--2"&+9D:#?#'?H(6*==&).=>9'135:.%5'H%'?-2.6F6$A@?9/5*:-3=$)!$34'D&<9F'&.+1A!(+FB2D1;3G7A(H".G@E71D.@'.-75,+&*'?@48%
@r1751
GCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTNCGGCTTCGTGGTAAGCACGCCGGAGGG
+
E=%F-3:<?9H#=D%@2/,+>&EB(&3B,**6G46D03<4,*-4(*,96H&24A%?GCE=5/+,
@r1752
GTNGGGAGNAAGACATGAAGATGCCAGAAAAACATGANCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCGTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCC
+
%'&1)C1A29791%HDE$(G"(9/;.,3D+,>2+-"B6%!('%A9)/?G(<3?,">6"E;5@.),#>H7+;3=")<$G>4'E8+F:++<$@;?1$,%3/.#):$<2;:#:)25)78)/9G>((D&%(+$6$D%-$578D?HG@9A+H?,3(E&#$$&&!<*#A3E4-8@1
@r1753
GCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCG
+
,AD-5B2?G+-9&F<H97#D"@G!3FB+F(1E47C?<4.?#=B?8#"$#2)CB-'E/%'H(="
@r1754
CTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAG
+
-G1<;5!HB$1A8&,-*#EA:-7?1(B1"@A,;>2:+:+1C
@r1755
GCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGANGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTC
+
>G*?=,90G;D(2'$6"D-87A6,<"*7H(4HA&!%D;4>;3+*D#6>#82'G++-DC7/D92=4=@0"#7=E/,C>'5!$+@68=1C.78;4-5=#&B#"9-2B,?-:#:($5.G*-)DE<,)!F:"D03G3$!+(!A:D8@A.$*G8H):;(&C5%58C8==E>@8(("A,:D*A+A%71<..*G:B?21GDB56D.,2.(B&
@r1756
CAGGCCAGTGNTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGAC
+
()'9E*<66AH18G>++>-C*A(,3BDA;?8B$@H'2%G$A%B-B934B32!DE:;4%)B+>#+.C@7+:&8/5%
@r1757
GCCGTCACCGCCTTNCCGATACTGCTGANCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGC
+
B75282F=!+$?7-+*%8'1G<A!3HDC/0G8.#%+;CCD*&0.$6",A@$F4#()-8<"C/,%0>G0*5.'?50"=G5*1)44,A>1"35<E@**A:%2+F=G$D!-=DH
@r1758
ATGACGANGGTTTNAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTNACATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTNGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATNCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTGCGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAAC
+
-*'BC31=</1;##BAC!C%.+7:B*7+AE&.173E#;6*;B)"H$/%FB5D!;3$.97/H*C(>;$B=!'=B/90D!*H%64/8'1BG@B*7)?*F<0C925C,&A7?-'C,;.<AD'*A06C$26-3'+$,+AAD>CG1FG?(.'/EG$31B26-:)7<.B-/#F"#3G;)(A'E55%B:;'!:*<.9"?35.G'&=B9A,!##=6,7B*"0(H8.A1B3$$C&<")2/A,D0(?/>#+$E'(78H670&!4?=#'6/"H38/'4+"5/:+G";7#%F=43.<(:<8(BC8GG??F$01B4'>6?%06/?38@(*D15?=E#+*DG434/8@G/,*<1F<)>CH'%0<*1-'#22/H)57?'97
@r1759
CGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACTTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGG
+
-297B:%%66=9A?E/)=+;B-HH%E59;>:-E(#H5AFC23F</@:%$&58BE-<6"F:H-C#1D'4*#B5,HCB6G;3"3
@r1760
NNGGTCNAGNNNGNNNANTCTCCCGGNGCGCTTNNCCTANNNNNAAGTGCCTGAGNCC
+
!#$$#$!"""!$$$##""$!"!$#"#!#""$#$#!#!!!""##$!$$$"#"$$"##""
@r1761
CACAGAGCTTTTCATCATTTCAAGCTATTGAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTNAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGGAAATATA
+
C0->$1AFG<76*%=>B1@E8.(BDD3*E6%(134@)50:??/F:8"%H'B9=A1;1>62+.&58+H(6339(4:8!$4=*3G/70B,9;G@C6<41E(;9"-F*?B1G1%C=A7/7HG=,&4!
@r1762
TCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGAAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTG
+
H<A/,HC/F&C.#:G@7%2$+?;1>4>/629E-0.&1#H>,!0+-$9<E082B"3:307!18F$/G(!@>%;G8B">*<>9#0'+2/%!68@$%/D."051%;944(&'0'C(A",-89/*!BBA2H4%8))19A-*20G(:F*;>8%35!$=@$A8,@%/)89//"-*&HDHC!#1/4B!>?519>?<E?E9>3+7>G5D1?H,$E
@r1763
ATGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTAGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGNCATCTNCCNGATGACGTCCGGGAGACACTGCAGTCCCGG
+
#-);//'/-2>2.A"D41=+/=(0!G+0&4:3'2E)!%5$'(A7"E2<7B.@+&-782!%C1*2G7!C'4(="1A&;2/+,(87<.*$E>,$.<8C0B$$,9!?G%D2*2!(/'3="$;D3/>1E+',#3.83@FA/G9#)!@))56!.$:A5(EA-D8B6=B.1':BG*=1$HD8<D99/7B4&&H"4$3H2.'>AF1A&E#>.4=F:710('/"2540D8*!<)B511'5!9$3+-)#!7$B%,!;1$&3%./G>50873G-/=1/8C!1&8A:BA%-!?A)
@r1764
AATNCNNATGCNGNCCGCGCCGGCAATACTCGTAAACCATATCAA
+
#*"!*#!*##($)')++(!'&&*+(+"$)&%#++)"($$$&#*!*
@r1765
TACTTCNTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTG
+
@&53/='B30,$';A'8>/(0<=$9B*./>0;*4?H#=!"&!E.:1:G.::,&6!@=&<E*3
@r1766
CGTGNGNCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACNGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTNACCTT
+
(&%'"*%!+''!&%**)*#+!&*%#'!*&!$($%%$"*'+&&"!'"*"))!*$*&)'+*$"+"'"+)'##'"+&#$"&+&+('($#(%'+*%'#"($*&!#
@r1767
GATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTA
+
B()==2$90(%G8.)%8:)BCG6.%.,=677?E466$&<5/0"0G("%(A=>"@*2#*5G&:-?C0D779
@r1768
CTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCNCTCCGGTTAAC
+
GGA##DG./AAC>@,09<92.5#('"D4(.1..F/9C,CE1:>B%1$?9;
@r1769
GANAGGGCAGANCACCACGCTGANNGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGG
+
*'"$&)+#)()*"%%+''&&!)'+!&$("%&$'&'!$#')#"!&(&"##"#("()%%'&&#'&*$$)!+#'*'+%)+(#%
@r1770
GGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGNAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGA
+
-)6AF>"=&7B9!(B<<>.2)<.*'"!8C2$C93@:.2#>.-A.1!40#/@%:(-#7)%&<&,H/B/7=6#-07".C1%6!":7+=-5&:!A81'AH,H8$#<DEE''@"):41,2A="'>*-
@r1771
TAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAANGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCC
+
C52%5(E&>"3C'?H2&B1H9.0(?,:G<41*;")9:9H?;DEE2+:?8+!BB&'6C0;5A!=**9):G.<.2,CE5!#C="%A4A'55$</%4F"E,#@'#0B4D6*D
@r1772
ATGGCANCATGCAAAGAAGAAGGCTTTGGGGTGTGTGATACGGAACGAAGCNTTGGCCGTAAGTGCGATTCCGGAT
+
%")#%&'#'("+%)+''&'*"*#(((!+('&'&""!&)*!+)*$$"&!&(+'%#")+*%#'%"%"+)*!)!()#!"
@r1773
CGCTANCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACC
+
7+7AD-71=?<@*+:-1-'623,2)0*$19;E>4H:=5!(=DG9:.2DD!=2!@B+4G*HC&#'E@0=/B4B-@%F$D+<;""!41/*
@r1774
AACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCT
+
!=,6.%69.7=B36;DA<<A$<3F:58363,.B9.,=-'',H
@r1775
TGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTCCGGCGTGGAGACACGCTGACCATCGGTGAGG
+
,AA:4GF9)(.@A(2A52301G'39.%5A2:,A-<)(@5"G->"8,$A.>G233=,80?-"H>1:&*)@67:H%4-$E/!!81
@r1776
NNCTTGGNTTGNNCCGCTGATTNTTAGNNGNGATNACAGGCCTGAATATGTTAATGAGAGAATCGGTNTTNCTCATGTGTGNCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTNAGCTANGAAAACGCATTAAGA
+
#$"()%('&#&#&'&"$'*!!""$#*'!'!%&")()*"**+')+(&*%#'&%!&(('%"&+"!+&#*+!!(+&$%"'""&+$($(($!%($)*(*%&'+())(*($+&%$'&&$#+&''")+*)"(!(*')"!#+)*!!!+"%"%)'$'*"!""&(##+(*'*%+%)"&&+$((!*!&&'("")#)%$#"!
@r1777
NNCNNCGNACATNCAGNAGNGTGTGCAATAGGAAGAAAATGATC
+
$$&""*'('%%(%'')#$!#*#+(#$+(+$&$#$!(!!))$#($
@r1778
TCNTTTTAGGGGATTTTCCCTCGTTTTNAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTC
+
*$!)+"'%"("'(+("+*#(+$*#$)"!'%*())#)(&"('*&++'"'%+#)$!&)%#'(%!#"+''$)*+'*"#'$)("#$!#%+(#%"$$))*
@r1779
GCGAGNTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGTCTGAACTCCTGAA
+
+;D?;>2/2E5=>;F,/C&=(;,)B(>1!E*F$'975!C79E85;%(,&>+415*5%+=A'4B5;:DE@+?1@@3A10'95&6
@r1780
ACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTA
+
1DH2+4/:F)>=2(9B#E8;8;/"1<"1B6AH*,2HFH,'7G7%@@+
@r1781
NATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCNCTNCCACACGGAGCGCCAGTTCTTCTTTCGACCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATC
+
$A9#C&6%?192D')11828&2+98)32B&>4):!*0#32DAGA7!+<,FGA!+$$:C!22?.',=39F4'F)++C(+8!;#3C+<'!9.0$";2G26.</&D(:D<$2.BA,&G>$1FD+<!.DE=E/@C-6(;C>@B<+#H=04D#$#@?/2F+E>D:11/(H(
@r1782
ACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCA
+
H071G(G.F#*2=<30'*8(:,B33D0%&%D.<C@/6@GD?8(@208:+'4H1H/&<1%G;*0D:CC)%-24?;,H&2/@7""!061=6"D@F@1H%(F2<!D"/2%EH"E3;?H
@r1783
GATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATTNTTATTACTTTTATATCCGCAGTGT
+
</,F:H8B17(@6F+B#H1F);FF.9@',DD*#/35-<F"$03<!4>-.&CH,C73'1@%"H0HGC'$@D7;/<16;G!C2%:!1>CC;3>$7/+6<,,;:'"&;>!A,!#D'
@r1784
GCCTGTCCGNGCGGTCTGCGTGACCAGACGCCGGGANGCGGCACTGGCAAGCAACTGACCTGCACTGCAGT
+
6<,6'C;,*1>=E#0-/8G>=;FH>D;C%E!$G4G+H8-:;B+*/;900"/?H23:/+2;?%;-9A=DH!2
@r1785
ATCCTGAATAGCTTTAANAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAG
+
F,%FGF45">;E**83@355)"*@F9+BB%1@H*)C92#?$4&5E$D04+5&$0#5B$2FB%+5)&!
@r1786
CATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATNCATTAATGGCTTGGGCTAAGAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTAC
+
@>&FA<"2)38*(3/=FH!&,F!B'F9?(!@A0.+&F'7!H%$!A!-E'EA1#/7(BG>E7?$(ADG)4:!2)GC<6C=)H3/#,G@>"3+"/'>"5@)5%0!"#;$AH8G&.,/9GEH"5E!2)3
@r1787
GTNTGGCCGGTCNGCGAGGCGGTGGCAAGGGTAATGAGCTGCTTTATG
+
*!($*!(*("")!+&")%%")%%%!)&$($'%*!+%%#'%#'+#!+(%
@r1788
GNTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAA
+
@1H*6B;F#61GC%>F.CG&A69H-;0B32C(3?F6$5;&51,?3F=,1@/19:)(29@.F0?:A4;A(<:>$3&;@C=.7;&"C"+FBB*12
@r1789
CNCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTN
+
'(1%1>=(3!8H&B#?2C<5H1&17?*%2)>%98&2GH5D))H%.?C=;8?@H93);1C14
@r1790
NNTTTCCAGTTGCTACCGATTTTACATATTTTTTGCATTAGAGAAT
+
)"0!7HB=6&""&&F!$)1*CHE$6.GB!<#D''4'7C+=H9<8'%
@r1791
TGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAA
+
@06.>C0.'818$$?(0D(A04C+0(!),<0&0BFH0,05,*
@r1792
TTTGGTAAAGGTTCTAAGCNCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCG
+
#82&,F09;*F,'$+6%F=G#'*FH0B+:%D(+?=*9H8#!FG1B><#%#.7&)6H"=H+5G-@!3*:->.H,D7<FB?""/E@!&5C;!E8A1-H;."E<"8%B036-&#<,:%
@r1793
GAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGNTGATAATCATCACCTGCAGG
+
29&&1*96F0C:24+"/%18B'B?E83291,'76*=0)2;-6#8(/85:6/-0F?42"4'H+A4E8<&(F=)0,&)>5(,)3(B#%9%>)>:!>3!/57#F6%'E5+>20G+>
@r1794
GCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGAGAGAAA
+
6;3AF5*B4;.@B%#7?=C!A<C=A:,85)!0"'):%827)F+F%A!@G)"+E+?4F8$D3<(75*D'!4-D+B2//7%1=D9"$51&#=(-#3FF=)!A;8>#"*3'@)'G?1G7HB(4(E=.,
@r1795
TGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCNCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGG
+
;&E59=&2)-F?E&@!>&..""DH5*,*?3*:E04-0&$A5"A#D.2(?5CF;CE,/@GF!.%.,2'&E;8=+;>3?$.5!G;+AD5F=?<-0-:&&&>3G)=H"G9:7>46E&%!,3>?3E<>7E7,;9F5'-(04=<!7CFA<3425&6$8?!946B<A4
@r1796
GTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCNGATGNAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTT
+
+H2A84-&:&H&2G!B=5:-4C>'E2>.=0"?;-G3"(!4E8B4)#E1"/4/FC$+>6$9C"1:5<4<$H:9H;>52D1;9?48-B=9
@r1797
NNNTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCTCATCCTAAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGAANNTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTNCC
+
'"!#+&'"+&$'%!'"'(")%"'%%!&)&$)++###')'#+%)!(++%)&)%"+%)"$)(%"'#+"&#!')%$'#+!$&+*+!$*+&!%('$"""$"!!#%(*'$($**'&&+%!*)"!'(*(%+##+%++*'$"+!+*)'")'*)#%%(&(#*+*"'%)!%%%
@r1798
GGCTCAACAGCCTGCTCAGGGTNAACGAGAATTAACATTCCG
+
*11?1/(G3AD@7CCB&CD8;G4H":8E!&,.90-/$F)-;F
@r1799
CACGATTATCTTTNACCTCCNCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACGGNAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGG
+
&!#&%'*"&$!$%"*+*(#&*++#""(&&&")(#$()'&+!&"!')&+!#%)('+)%#&*%(''("$"$*#+#'%+"(%!$*%)##*'$)$%(%#$'#*&%)%&#!&$&!(#'+(+&$%#+$"!$
@r1800
CTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATNTCGATAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCANAAGCGACGGGCAGNTAAAGACGTGCATTACGTTTTCATGGATACAGGTTG
+
;+0A,H815F."4.A*/-$=6?'1$9$+$%G;>-F.-&05*C:$*G$"&:65*!-/*D%@D1E/1$<'05=<C74?D2#9B80#8)+=7/5E?G,9G9"@<,%G?;0;4/8?9*7<%"62'55F40-*F;.0/7C#((&/F&28!E7,5;F$579@+
@r1801
CCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTT
+
CAH"=/B3>F$)72<=H:D1##G<):3/"E4CH3#%)H">60%@A-(%%!8B4
@r1802
TACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGNCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCA
+
(9E8C>4+5",*+$>;F$)5<?4H6.7ECE=?*(A.$/A=E=E>-!4,+@2:092675#GB1A6/*((?><$C%HA7!508&1!<%2E.1>C#)H4F!A#*??=E/;#*)H0>&:3#9,4%A2@78)44-G(E@?8@!A.(B%C)**09ECB,GE!:&8C"AD+"9!D+8CBD69@7@9<4B/?5<G,0GD>+#10,4)9.E2F
@r1803
ACAGGCGCNACAGTAACCAGCATAAATCAGGCGACGCGGCCAAAA
+
3C35.6$1'<H"D:4<&=8-71%!G+E&!=%&#@:+4<#'G/:#)
@r1804
CTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGACCTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGGCGG
+
%>>A0(3'+9&/?%+B6A;:,,408?H9E3C%H34/77<76:6$+"?"+2$=@?:2A?'2G=5.=0291@#(E<@%;,93CH,,9#6*26H?FDB!+5679$GEA.(G)03*.F>0416.4&.&!($#6<BB>*:611%"/=$H.B5>+.+;5229**:7*5,,&2<=7;7:%7$$&-6AD95($$7A+&E*@<G>::,3?,>&C6;+'F,26<,%16C6C"</;7"39(3($."*&**%#1>.+!$%2''39>;"&&%DE;%%D"D*H@1!)7?
@r1805
CCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCNTCCAGTGTGAGGGCGATTTNTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATA
+
.<=*(A)HAG9G>"A;;->*31+8<;?'$4G=7$*"#'!/F?GA645"!'(455D(F@$*#B(.352=#G6)42C,@,D9?6"&90.!B@%$3)G?"1
@r1806
AAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAACG
+
4>$'A>(,$3#:9-">7/4?%$0>C)-@'0#&-*9.4#B*&9'DG
@r1807
GGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTT
+
BE'%B9;<A?@3"9%8>3,!8<.(6@$)68C;+-$1C!"#=GD6)$5,G0*?F>C*)33GG98+65)
@r1808
GGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGAATGGCTGATGAACTTGTTAACAGCACCGATGCGATCNCCGTCATGCG
+
?0A-B43F.-/9+B42$.?,8.19'4,?C(,,A#>!$G%#$%;A?>$F/CF-<:AB).>G3D</F+81+372=@.27+9G22AE,'0F.+F$G@$=
@r1809
ACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAG
+
4@$)G,/*%#<,35/;#==5<,8%<E'?DGA608G*F$4#2>%<-G<"8'5#,?E%70,,@@/$43H-D
@r1810
AGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAANCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGNGTGGCCTGCT
+
39F6<3A"F8@)0>C$B:-7'/<AH)=4E40"*'<'0?/2E3,+8&#=51,55&*E95H9CC#,F&,=6!>GD>?7-1;8</F'?,?D7+)4.?%#5/6?'930-F$65DBH0F)?$37F$53$.
@r1811
GGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTNAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGNNTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCAT
+
F>;04>H'<."?7<!F;H1/C@F%=/B/='AD:'(?%E!>%A!DE38$&)15).1G%B->",:-BH$)>D!@.F'FC*2EH8GGD3E/+++*6+CC2&*.CF./B$F!EG)/%*1H:HHAE0;6DGE2F428!3BH7D!+20=)?5-8B"7-G'@&>#E"/C"F>GH)+,2G8<C.<&+&%6H0*,1)*(9$#A!)"7C%.9@''74)F@<G/8+*@F
@r1812
TTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCA
+
>4111::)>!3HB2.*:-G&D>26'81!F)==4*CH=AF4/??C6(38%85)$5+-8:1"48=7".>3*2788"164B?=?
@r1813
GCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAGCCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGC
+
5%%'"-7A(.?'+D@&E>@B;#14>:4%0%.H;+>'"?84?/470*D?DA<3+D3$F3*'+F3/CH!*G8$49C!/D;(!-G+H&DD)#".(C%%7A#*?;G&2.D6FD+#(%2-$<96?7--95CG$B)G49=GH8#=2.2%:->E4;48F
@r1814
GCTACTCCTCTTTTCATCTCACTACCACNACGAGCGAATTAACCCATCGTTGAGTCAAATT
+
&&*)$!&+*(&')%""$%!)*(!'*(&*+#+$!!$#"+#!(*$#!!'"#%&$&""'(+(*#
@r1815
TCNCACNCGNNCNNCANTACGNNCNTNNGNNGNGNCCNCTNCTATTCCCGNGNNNANNGNNNTNNCNANNAGCNNNNTTTTNNNNNNNTCCANGNTTTNCNCTTTGNNGNGNANTACNNACAGCNNNNGANGCNTGGNNCCNNCNCNNCNAGTCCGNNNNNCT
+
!#"!!$$#$!"!"!!$!#$!$!!$##"!#"!##!$"$!"!$$##"$"$"#"!!#"##!#"!!"!##!"!"$$"!##!#$$!!!!#$"#""$#$#""!##$$##$"#"#!$$$#"$##"##$#"$!!##"$#$$#$###$$$!"!"!$!"!#$!!"$""$"#"$
@r1816
GTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAA
+
3H7-!@=+H',):@>*,6%33()H$-84$09!G,:*H@#&;-E)&4>GH'A;.7:BH8F?<&"=!$
@r1817
ATACGGCGGAATATCTGCCGAATGNCGTGTGGACGTAAGCGTGA
+
E,C)6"<-9=6$6)+-05;=BF;FD#>1H'E&<9:/0@2@8$H'
@r1818
TATCCGCAGTGTGAACACCGTTGGCAAATCGGCATNCGTGGAGGNCGTCGGTCGGGCGGGCGATGATGCGGA
+
DG8B"(.1E9@!44A()@*47CDA7!1/E,-"#'+!8<9-/9':108/55>0+G=,;.%8%"05H61?(%/*
@r1819
CTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTT
+
8&F8#-@G%%,8096!;F>@D3<9;.C1!."@E523G(G9#G2$:!@7;@&.6&51',8#&(''@./:52-$.'2(&(98$"B2%3(%0"32.)+,-:"5:;-<,!B7A7F'8
@r1820
CNGCAGAAAACNNCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACC
+
!#%&')')(&)"%&+(!!#"")"'*&)$%#"+&")"+"$!$"!$#")(#"$""+""%'&'*)++('$(!+$+$'++$*"($)#*!&&"()%$*$%'')
@r1821
GAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTATT
+
A#$(@,G@<;H$;+$9<3$))%'+?$GA=%#6G6D(6H?;D.=
@r1822
CTNTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTG
+
)*!+$"+*)+%"%(*!'&)!'$%(($)""#")""!$&#&%)*!)!!%+)"!(&%)"'%)&
@r1823
AACCGGCGGCAAATATNAGCCAGCGGGGATTGTTCACCGTGGTGAGTT
+
G-+D@7?%HC:0C*E!"@%8;1';;EF&+C:#&D(;*"(4//0?4=&3
@r1824
AGCGTATGGGAGCTGAAGCTGCCGACGCTGCGNCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGNTAACCGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGC
+
&("<<":@)":(<*/=#=4E$;(001B39&97'C;.<=,E5E1(<783B>')B0;7!80(>H>3"G1HA7G6<@83E=8+%:?HF(-GG64E-''#9/;DE=)3?2A@+8*4#>'!*4C-.-!1%,#G<>8@;"B;*2G4%$>@$217%2B<26B:6>CG##@'@G3?C"?GB6*(,0$9B1C@0=4#>!+'-'/;,E'
@r1825
TGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACGTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTNACTATACCTTTTGAGGTGACGGTTAATT
+
D,("1D<=F6:B))9C)+=#+;E-E9D56'+'+&:9*+AH-3B?>.(E54F$A(!-)(%C:<C,BB*@)9/>&1'8H@92'9B+25*B,G-=#@8B8>33"+@94;)
@r1826
CAATGCCCCCCTGCAAAAAATAAATTCATATAAACAACATACAGATAACCATCTGCGGTGATAA
+
#29<E/.+F:(C6;D/GB%"$@D(9899/A,5%)74=FA<;6?E>(/G/9>C(C*:78==8875
@r1827
AAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGACGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAG
+
&A/<-G',459:!%!?#),(8-=#E(>%(G)-1<A79FC#=4F7A*)B1?-5"("@"2$>"+>9$."-?,BG<9<A(G8/=B5&'B17E7D'0;180B=G5$?G$81+:)83#1,$#,)6=D-4@
@r1828
GATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGNTCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCC
+
?A=%*>?B-,/'3+D(-F3CC;/&C;H<1E:=#?;5AB>:8H54E#F$FCD%!D?-E'2;4(6FE>G0H:2>$$8781-G9E2DBE+7C0!0H/:%.=;!0%<(9"0C#G(<?$C@!0HD+:/*2@4'B)7C#!'076;7&./72G$=@?,C0.4$&!
@r1829
TCAAAANTCGCCATGTACTTTTCATCCCGCTCAATCACGACA
+
,<'$:=!=.="7E&5F>3C:)(5*.76(%?1(9$/EA/@+A?
@r1830
NAATTCACAGTCTAANTCTTTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTC
+
'(5!=E2@=AH"EAD=537!>#C92%3'>(?@-8)&''+D.D-E7ABD60/1CC+&3%>C-&,>-7B6:H@33(06FB&
@r1831
TCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGANCACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCA
+
8:B=B,-1:28D&@1=)GD./@)5@.E&$D*76C*+<%54C!9F6&$C!<0#76.CFF1:%D,)?<,)6>2+.>%9>#GB,6D6C.<2@8@,)#7<206@+GC&G(,;#56;BA$13-C$+%(@:A='+7D&5<;76)H:6G+6/-3*B)7!/2BD*>#
@r1832
TAGNNNNGGGCANACCAAGACAGCTAAAGATCTCGGCGTATATCAATGCGCGATCAACAAGGCCATTCATGCAGGCC
+
!!$"('#+*$%(%&)"$*"%'"!""!)#$(+!"!%&$&"*(*'%("((#%%#+#+)*#!)!##!&!$"!')'(!(!+
@r1833
AGAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACNTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGNAAG
+
'%#+""&"+'!!'(($"))&*%%$+"#%+*!$%$$#+*"))&$""(%+'!$")!*&(&)!)"!(*''"+"(%"*)!&##!+%$(#'*'+
@r1834
TCTGCAGCATCCTGAAGCGGCGCAATATGCACACTGGCTACCTGCATCAGGCTTTTTTTTGTTT
+
*0=5("$3<,B3#-9$;0('->3=<*1*&B2D.*C4.11D#@&D)8E6G3<0.C/<13!*#3;$
@r1835
GAAATGTACGNNTTTCCTGNTAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAAT
+
%$)'*$%!'&!!+*!!&%!!'#$%%*($$!!())#*!'"%(+#*'&("%+##!!)+$$&**#$&(*+&!(%'!(#*+(
@r1836
NANAATCNGANGCTTGGGCTGCGCTGATCCCACCTCATTTTCATGNCCGGTCAGC
+
")"(($$!&$"%&("#%'%++$'%!("+""")+%)!%(("#%(!%*$*"$&$'$'
@r1837
GGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAAACA
+
=*228!=4E!#*<!8F%8+2>:+C535H1B#ACH2%H39.B>B3(86:<0F<&=%
@r1838
TCAATGAGTTAGAGTGTGAGCAAAAAGATTGGGCGTTTTCANTGTTGTGCAGATCCNGTGTCTTGTCTCCTTGCAGACANCACGAAGGTGTTTATGTAGA
+
&0"4<DCE6#GA*H3'7,+:=51?C5DA4!DH66)GE?"$8=/'@8$H/8.<(6(B0,E&FA==230006,.'6)1/;G1$+(#>#+7%>>41)4>,B6@
@r1839
AGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTT
+
3$;C:*%,)D0F&A?87!F#E?"G?0"DB>B!(E=1,+'A
@r1840
CCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGA
+
-(",AD$>:6#3)+/9$G(E(7!:/D1;>!)BE#*>4D5-FH4*.)."4/41.1G,*@A,B3?:(AA5E45!"%BC;">B>">/-<1,/8+<;1904CB%!54E.
@r1841
CCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCC
+
<H&86D$=A<C<B?%&66)8#>D!H/,->C63H0*3>HG<+',1$.528@;,0&A0B03$D2*6><,%"+5*6H*BB>B0&%D:-$42<"C&!.$%E=$+'*"'30H0E:F1$=D>B2'<2FF?(3FH.5?F@<9@'GE6$9$@(EAA&0:>8$;(;3-,)/C'4*GA'4D>
@r1842
TGNACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCNTTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGTGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCN
+
3,=2@?C-(G1%.,=8):C?.18E5BF&&<6C95%+3<%71B)-*<#/?GG9'1G!D#A<CE3"@3.C$H-43//D3!'*"9%A.D9>)><:F/H))&BB2+F3)1,59<:&$8<'!A>>2$C&DBB?.FFG%1)"(H';*-70,,$//A4:A3!;4C2)%G6)6/=$3>%<,8,/&/:9$@7B5*7"+*'4A15G?/-B;8:-,:C.2;88."-'.((,A6D?-*#@"+$
@r1843
ATGGGAGAGACAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATNGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTA
+
2.(C"E!#AB+02!>"":'$9.44C'A6;5='<G-8+-7A<6.:-&,A,1.@01/,&<*1>G:02B,+C:;0.@G":'')H+&,01;+E%0&E?29D-!6::<).<D'$%CAE2',05>8@2&+A/(,$*!A8'&(2;.C
@r1844
ATCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTT
+
$>-27(7HA-?+#BA7%D=C2879')'BC)=4<3&(D92"4/:.,;'4%,>A-:)&$EB>C2>873.:?H7.-9&*F"&970";=6+>?96:5
@r1845
AGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGT
+
&81C8C8$<325!*/#500FC81E:??035C7(-9@+:))C9#-8F/>9-=*>9C?;5552&.<E&H@1-6%/BD==#/:-:2(D#4!/B#&)<#5>3%/":2,C$6>3)CE;
@r1846
CTGCCACTGATATCCGCATTTTTAGCGGTCNGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCNGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGT
+
4-2;F57B=:3";C).>;9(7!/.7$:))C2!H4"A.";6(8':E5=4)>+=&GE6GE9,+B'HE$9GF'501+;;,!C1(!:.10E0>5+*)"=G/:1#)!-300.68H5B@F")BH;6G%9$@6#(DG+:>
@r1847
GGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGNCGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACC
+
@,?2$?C3A92=:C'.+2!#6+3+F71+.F,:#,C".4)%B?AC-7@&21A+75-C5)C!5C&$>%$B!3?F1E/<6A$-'2BDA<,2@A!*>E<?9@HE
@r1848
GGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCNCAGCTTTTCGTTCAATTTCA
+
4(3(.H1!;;466<50F9(4&+=)H<5!'7$59"H2.D5*?8$4(<4'AFG#-CD>A11)42<3AE
@r1849
CTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTAGACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCC
+
618=4.6181:B>;>-?+.!<6=-?78"1H:<(%##+;$?EE?47$@"FEGB77/@>G,-:7+$#G'2F%/99'+<'E%2@:9@/80@D8G14%>5%'$>'B""!1:C!51!#<E/?5CCD2<>@+(=?H51&9)5C>4++9."G.A6E&
@r1850
TTCGCGNCGTCTNCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGT
+
2&+:F-34&'@!$5396FC$9"CC;14H46<1?5:"..#F(74D4)@/9F620
@r1851
CCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGG
+
@B$!73$G3GF,.2A/G@'E&)=;3)H'%&#-A9F7A8=+13#%GG%E9&3#8+'=/FB*$<)2:E<',3H9F3%<07,
@r1852
GGCGCTNTNNCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCNTCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGA
+
&&*%('*(!$(+"$('*&"+%'+$#!%"&+%!*()!%!!)$&($$*!%'#%&+#!(!**$+%"$)%"$%'(*$%*!+()(('!(&&#(#'%'*"&!"!()+)#))'!%**#+#))*!%
@r1853
ATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATAC
+
.00+'"G)9#A%G2??:<27(2E5<%)>#&0'E$C,>:F,5/C.G3;7&=;81$9136440A42-)E7?@*,<BH?#62
@r1854
CGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACT
+
G-10AH&6&9AF3%A2BC5#*F;8'$35+%6=(6!@+=>=.2E3'/19=!("HB=<1);A02)6*14+&8!=7A6?'D+4;D:-1?9D1'F#6&+('3/,;7)+F#4#6/$;*(6$)F>(H//@*:</:D/20?*
@r1855
NAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGG
+
%*=;0/:-8"#6%77,6C%C-8>4G-31D3(7,67>87H(F>C2//"2A-19A9@-%D"EC*B">
@r1856
GCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGA
+
7?/H:B'.5--02/;)"#5;,<2A!G0#4=->.59!D-;#G$2#42#)3-EA++B<2,
@r1857
TCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGG
+
4/4".(//&2/!")&84#:/=26%BD62;0$2D2B+2@=1=,&9=H?5.92+(*.946-;>F-0&=&9)3#/#*C20-',@>,
@r1858
TCGCCGGAACGCTGCAACTGAGCAANAGACGCAATCTGCTCCGCCGACACG
+
9%?>%/4<G%,5,!9#F:3,D3(-AH)(=(B$92(%-7%C)C0(.:E<205
@r1859
GAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTNCGGTACTGGAGTCGTTTCTGGAAGAG
+
/")AG6E'7223&?6<.82)C0=<.8F!(9=>HF*4D3-1%F>$<DH&7&-E2G0B>--2-()'6<E%8.)%;:5=2&-F+1+)(5&?-+#4?A.!5,
@r1860
CTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTT
+
FC,'G)'>%&@8/EH.G'?)<B,61-5!4.*/D"-*3,0>?#'1:>B!!5$7'F</51,3D(G8(14G@2C(!&;C.4C1/D9"/!/&5174,+!#;!B;>6;5+CGA5'%=A?E$H-/1C<698*;3"D&$930.=F:"==%E$0D>)6=3E2'&26*?(9E9$87<'E3=33DG40#";A?-0,6
@r1861
NAGGTGTCCAGCATCAGCGGGGTCATTGNAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCAGGTAATGGGTAAAGGTTTCTTTGCTCGTCAT
+
!89D@A7B*A'2H;$0B!$%3CE%3,A/,8%'2!#-',4)/(.;*0?>12<2@$DC56!4D#1*"&82C8(E$<,)G6D,1-"%@H&F,<464>1=<07;0=7!F$5'57B.,BD)'H1>0/880;(2
@r1862
CCAANGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGNAAATTGTCATTTAGCATGATACAATAGNCAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCCAACATTAATTTTTTATGATAAACAATTCCA
+
1!)&*3!#(403-%,$@9'@$$81.10F%'-181EF<C,2F<&AG53F>+H!;=*@@)5F@G&>B-?6$A.,F1?E?-2:'?4!0=+934H0:$*/31A9G2$(9A..5C;!@H9>.G1EF:95"DE@(0-(*.GH('H"63(C..!7*>5B0BC;?EH1/$%7548)#++?&.=)'(:F,5HE7-&?D7@?,$A$:464.(6#*60#%AG)A/%$"29<:A:0?2AD5<#1#26:8(#"$!?2).HB+1+$@B*$@=1*+=:F-8<-2B&>"C;+8:%F(8%!E7A>?.1@8828$'
@r1863
TGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACNGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCTCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAAT
+
.*#9'752+@&;E0:1<8>H&,+.7>>(A6BA!930<B$$=$*=A!E,.'7(D.(269C%8="-H&G-*$A$1@HE-G=D@3)H>H<,/<5F;1#0,1*4-3/=>?(G"G$G1$&4&6F*'(6@#>2.<#H$=768+1/E"?)GF#517G8"7)D"<>@#<##*(GD>=5C!:!*@"G'2.)7B%06<#@H:B$<@F>$.@6&"B)3&B=3<+.6>+@$4B7@@;>?@#H4<55/)/H+0((G/;-!%:";F!/@!)A0);1$:00+1H0*&D0&1)9,9C!7=#A
@r1864
TNATNTCCGNNNTTGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCGGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAATTG
+
*'")!$$&((!$"#(++'+*(")$!*&#')"&!'(#!"!!&&$+$*"(++*!&+&*$$'#)$#)%*!'+$("!"!$$"++"'+"(&")+"##*(!($!(##"*$!#*&#(&''$'#*'"!'(++!&(%("#($!'#$#*(*#$(')%+)!(+*#)(!"(+'+)((#('%$&#)"&!'#$%($*!'(($%
@r1865
GTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTNTATTTAAAATACCCTCTGAAAAGAAAGGA
+
/!=#3,;F.(.3#"#;2DAE#;@0&"FD&!!#=25B>@G(;4#91,H/G'G.&DF($<#8,;HGH5#H>1<GDE*.'$3!C:;'@+>@D>"H>$"*#EE*D48>2=E=C%41@F<!!*8H:.#,H2.F>#6"9-18&$,/+%:FD"D$6=,)-.%&$)&84C
@r1866
GNTGAGCGAAAACGCACGTTTACCATGATGACTCGGGAAGGTGTGGCCATGCACGCCNTTAACGGTGAAC
+
55-%<D=E03F$#5-E>AF%-54+5<!E:/9*)7G0G$CF=>.F>6H',E&H,-2)!99$(<<)7!>%H4
@r1867
ATACCCAGCCTCGCTTTGTAACGNAGTAGACGAAAGTGATTGCGCCTACCCGGA
+
1F<(<5&#$:!F4C%%%>#*-'7)!<9*,B2E>%9B6>?.8:D,@C6#/);%45
@r1868
NAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGC
+
)B62.$E0#EHEB%A=7@?C'(-)$/C.8;!>0A)E<:7D1D7F)!
@r1869
GCCCACCGNGATAAGCAGGTCTTTTTNGTTGTCGAATCCAATCGTATCCAGTTTGTTCATNAGGTTCGTGTAGCATCC
+
:8HD6;)-BC/DE/#6)GGFE3B,7)2G>8H*B,B.?E6-E,%;%.;@8->H;>E;#;.:>G6>7C:<*':F&>,9>B
@r1870
TCNNTNANNGGCTGGNNTNGCGNNTNGGNNNCTNNNTCCGNNNCTNCNCTCGNNAGNGNGTNNTGCCTTNTCG
+
$$!$#"#!!"##$"$#$$""$""!$##$!"!$!#$##"$#$!""#!"$#$#""#$$##$#$#"$"!$"$#"!#
@r1871
AAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAATGAGCAGAACTGGCGCAGCTTCACCCGTT
+
)D%8)2"C!6977"5)"5/%:F.:B8"2E%779E@1+;76&2(&F+().EF68"E3FB/<&F#!*<168'F7,%$73H/74"H))1!"B41"7#2
@r1872
NNNCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTNGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCC
+
'!$D"6(#4F1)07%A))@=G<902?+D+@2;9:H7"!C2@E?-A<1?HH%17AAF#8!?+FG?6+5$FEG81*0E<-A"":E)D"(E*8@(@GB8+E@6FA31(<B5))"*'-4:G"CF)"
@r1873
CGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCA
+
55$C'!1,C/(?H9H:DG4-,80!##-<3G)''&?:21?%2-7>A?*);<<2+7>(:<";@GC4-
@r1874
TGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACNCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTT
+
+.8?7=@/6FEB,*!C@1D9BD!#61FB:&:76,*,';3B@%?F>:#6;=25+52:528*/"8,%.8)=>,&*#%1+(*8&038H,,7<54,@&;*'(::;%1,4=
@r1875
GCCGCATTATGGGGATNCTCAACTGTGAGGAGGCTCACGGACTCGAAGAACAGGCACGCGTGCTGGCAGAAA
+
E%;53;B<2&00C*@F,')$+B/3B'H.EA9+$HGF3!"!.EF=8@?E72"1A+5G*':3%/1"57H?4$*0
@r1876
NGGANCAGTTNNGTCATNNNNCTTCCATTATTCTCCTGAAGATAATAGTCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACATTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAANATCNGG
+
#%&*"%%!))!"(&(()!%!%#+&)#+*'$)&+(#'$*+(&+'"!$*$%))*%+!%"*%#&!)!)&!%$#+!"%)"$"("(*!+*'$#!$"'!*"!*!&!"#)""#%&*%)&!#%(!%#)(+*$""+(*!&#%))(*(!')%+%#%#&*%*'$!)#(()+"'#&)+%$($&++#*!#*
@r1877
GGCGTCACTGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGG
+
?0F9044<B=H'<'>9()&&H,CC%57G&1&?"<)F;/)76HF@3@<3@7#>%%(2
@r1878
CCGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTTGCACTGGTGAAGCTGCNTACTG
+
*":$#88>A1::ABA9BC.G3>+>2*42.86HG)9&>>.==C"8:<4$B5;1BE(=)1?+#97:!5C"E2!97.-*6">(>EF0:,;((<=D;+>"9C-6E01F'@/+5',"G)G"3:@,$%!?2%::DFG/1
@r1879
GGGCTCNCGGACACGAACTCATCAGGGTCAGCCAGCAGCATAAGCGGGGCTGACTGAATCCTGGTGAACTCACGCGCCGGATCNCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCC
+
#*"$($%*+!%"()%$)&+*+$(&$#**)+"$+$*((!"*$'$$)('%!#$)+%*&+"''$()#"*$%#"'"!%#()*+%#&!)+*!(+!)#!!&(%!)$%!!"+!%+*)#!)'%!)+*!"+"+')*''%#
@r1880
TCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAA
+
AD"7?<*45>6/!4"=.:.:;+"(3=F%3.-:H1"=E.<+18:4.C0)3G
@r1881
AACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATNAAGCCGGG
+
9-7.3H=6-(5*//E5>>27+9>)!+FC(4-H#&C-G,E96"4+.+?,"0,=A6=&07CHG/+$%53G.,;D3!5H45=)+%04H<9,DDG(2<3C06
@r1882
NAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCANAGTCTCATGTAACTGCGCCGTTAACCCGGACNTGCTGNCGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTG
+
#+"($&*&$$+*%#+*!+!%")*+)))+")*$%(*#&%'+&!*!%"(#*%$+"*&$&*(&(+"'!##"&"(!)&$&*&(#+"+&*&(**""%%)"%"&!+#&'*+%%*"(!&)*$!(+#')("!+!!$+#$%%!!+"&*%#$#$)(!()$'$"))*+!)(+#$+%!%&'!))$%&
@r1883
TATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAA
+
=@>232;%,8E*)3':0G53C6$$.7<8?.5$<75@*?A6$>889E5-&D,:+,=>1!=3F<5##+E>,>H,==$;<$($A%:>4#8*41A0C%//
@r1884
CTTCGCTACCATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCANGGTCGATTTCAAT
+
<:&8=.3=GG1D765,6.)D!#+=>=C*:'E;,91EGC@')B-?6,)1F2+:G,*40%@D4C7#7;4C)%?25&+B0$H7B<9#*!/C*7G($',2<'6.F7A2:?7)*61)@86D%*":D4E:F1%B%3>/7?5*6+*(092G:G8C#B('/G4#G-D5G/1C"D4H!@%%7,3?7@D;;9!D8E-:*7#B>B9"26'3+,A")C;07/:0C8D,9+4.GA8C9,@C:7".F50;'&=5D,+81D
@r1885
AAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGA
+
(H*!''+$9#HC@>$#4(54'*+:0E#@4*73G&3)45<=7>803B<4**2G.0&1#C.;*-!?;G=)F,
@r1886
TTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGCGAAACCGCCTGCGG
+
'="3=+3@2.>F/EG522+7'=:'%A)=)??0(2111$#$A!6&C*.*@%D8,DA3,3%C%:''9GB"%*E,0?@&/E:*#)5?.?;;<?6@(('+/7<3FFE$9#3<*C7=359++)''HE$,24A$3&=9HC'>H!F+FF8&+.*E)9!,C'!D
@r1887
TGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAACAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCC
+
2$%>947D*=B2+.D"2H"#<"D4*@691>D:?:4EG0<&4=;1<0'C(2%G$*)5;@;FB68)>"7/(5.+44&*7'6;(24*+<)!F+2.'AAAHF=A;4?E3;,+>C+*%<69!4*.!>$H;>#3.@-9H%-37:/+6#5E7.);5&92C=3B;:%.##&9/%@E*20.?A;54)H3,4-C@0(F78@A:;B"!$@B5A>1:.E#8">D"E+.A+:5"705%B*(?0"C@A$3.0
@r1888
AGAGTAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGA
+
6$1>3$;+01A-1=,D.F;H1C("<@@=87%+;0%8F+3H,(!5AF=?
@r1889
CNNCCAATTAAGACANNNNCNNGTCCNTNNNCTTNNTNANNNCATNNNNGNN
+
#!"#####$$$$#"#"!$##$!#"$#""#"!!"#"$$!#"!$!$$$!#"##$
@r1890
GAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGNTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGT
+
=4<"-8F%/DE!30@E:FB.A2&8F::2;!(8!?"F;1@8-%0H%B$%(8#(E":<*6@1E+@.>?9*F8>.#<!,2;%**6HDH#)A=)@+3"1;4@+H((DC88@@,;H0E:&0#($)(,05D@!24D!>C7.3#+=#3=/@661$E/D&.E</*9<9)745/8G7BDBD$(:?,<+'08
@r1891
CAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGG
+
&E*B7);7:19G5/2CD4-%'H<G&B0836::,>6#3/=@A'%#
@r1892
GGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAG
+
.?$2.6D$3AA)@#50:(#B3/=!()%:'B,+999*-@(>@/BE%;6'.-&4-!/A#%BG!$;;)6A:C5+$(G=-7?><@E)+7D!,15:?(#>$1714685)#&G,9/FH"4#"1+E)91;)8&05=98062?5/*
@r1893
NGAGAAANCGNATTACAGCAATACAGGGAAAATCTTGCTAAA
+
"&)'&"#!*'#&)'%+(&(+%*!)'(!(&*")+$"+!($+%!
@r1894
GACGNCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTNCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTGCTGATCCTCTTCAAANGGCCACCTGTTACTGGTCGATTTAAGTCAACCTT
+
('!*+#(")+##)!)%*)"'%*''#$*")$+"""'&("&"'$+('$&+)&)'"$'&*(*#%!##$'*&!!(#(""&$'&(#%$"*)!"*$!+""%%&($!$)#"*#(!#!!*&!))&($#(%!("#&"(%&)!!$'&"!&'(+*)&**'($)&)(+$%#&!%+#&*+*("'*$++)+%*%*+%#+#)
@r1895
CTGCCATCCAGTTCCCGCGAAGCTGGTCNTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGNCGTTATTCAGCGCCAGCGGATTATCGCCATACTGT
+
((("#+"##)'###"%'!%!'%!(%"&&&+((!)&%($+)(*%)$(')+%&'#())#(%)+()'#$$$)+&$%'(%$#((+)(&$&)!*)"()(+#!&
@r1896
CACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCA
+
G/(:"BC<942.,55*8BD8(-%%3/?-.7;=1,'C47/)%G-/)*;01,;50C7DA&B"!F)#=3&%E#"!AF,,/F'488
@r1897
CGTCNTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTT
+
)H<H@86F=7=D8'90<101#71$6-%*"G0>,1E,=D#">%22:'C"#D1EABCA0,83&A'?)4F#7+?.''F--18=)-8(3+."=<2$+*E;)@#:61%1,91D"7:D7;#8"$*7/>&+5G#:!27(2HA<>2
@r1898
TGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCA
+
G?(+9)G858318?%-*4&:+7.*A0GH;2?:)>D.;2$6/<..2@,C)7&
@r1899
CCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCANCAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAATNGTCTATGANGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGG
+
1&'(F8>7E>=8)!E!G%D;A$*54!<B*#-2H&-D!>ED$A:,!E>2E*',*?*("';8H7"DC9%GE@(F4?!H:DB"B16C)>=)1/*;1AEC7)$E"?&E>%CA&0:#F5A>??C3?H7:9'!F@#40=@H+A5$<=2FC'F;9E,CC(0#'#6!(;6>(CE0A*H
@r1900
GAACTNATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTGCTCCGATCACCCTCG
+
C&>+43;'"H1*+4E-1E:38"#.!51(=H<0/457;B,15>"8+4+$-9<#DA.G9;HD-320FB4:$E?:-5!H<8C!'AHC2!@%'(:
@r1901
GGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCT
+
2$D?(4$9G2-@?42*;E2G2;4,26@6.7#=AG($4$E@BA<D;-3"*#5!-80FADF9B!1509?=-:)(E*
@r1902
TCCTCACATTTCATAGGTAATGACATAAGTCNGATCGGCTGAACTCCACAAGCCCGCATCATCTTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAANCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAN
+
+''&$&"(#$((+')$+"!#+&*&"*#(%()''("$+&()(%+)*'$+*)($$*#!'""(+$!$'&$'&*)"&$"&(*#&(!!$%)+'%!+#&)$%(&+%)"'+*%!+$!*%&*'!$))$%)#+"'!(!!+%"!%$%%+'*!+(('!##+'&!&(($"!$'*!+!$($*%$#)%()###$!$""!))&'(+#)!'&!$&&&)"*'!'#%'&%+"(%
@r1903
ATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTAC
+
C;:*75-(BA>+;+2B(%1*A(H&:#;?>%+F%'H81/(G2@.&>483C!/!)
@r1904
NGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCTGTTCGAGCAT
+
+'!/=C:8%A<253C&4<F;G=5-.,7.+7C"!)-#C:=,?E'$,+H7=C3.'(:/2;C/@*>((FEC
@r1905
TTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAA
+
C35>/+3BH-B0?>@!0?H=AE*31-G#892G02/*F-H),H."D*>D.,
@r1906
GGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACTCTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGG
+
43C4&5:1F(C#,H8<&D6:(0BD$E/2+,D276C/BG$G<0+29G;#;?8D*"-C7%,1E#)1%:@<?;9?99?D%!BD<+H??0"%@8=?F59C%"G/,=9$.G,8+GD)F/#$)<B%+(@FG>8;0B:GBF/.,+;<>*'28/3*;):,(G$:<9$+F@9;
@r1907
CAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATNGCTCTCCGCCTACAATGACGTCATAACCATGATTT
+
F@$5(C<,=BAE9F&H(=0$6:?67=6:3H8=7C>+*<$B/3@'HC,#7.A,@(9%#=C<%<<@C573&G;EF3EG52D0DH>;$AA.132:$5.<.GF&+H%';1*7:9@>7*GE!9A>)>C2A$-=C*>C;;1!02
@r1908
ATATCCNTGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAG
+
(?056%D/D/$?5@95$/A>8!?,E@;"#8987<25A,4:(5#/(#'D>2D=6*
@r1909
CCTGCGCCACAAACATCGGCGTTTCATTCCCNTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCNCAGTTTGTCCGTGTCCTCCATGCTGAGG
+
C)73*DF#';*&(D46,(36-04#!7,;<?H1;B)=%B:B0#-0:98!A90'&11(.FA?EGGG,+"=)DG1C.C,8H;<7A9G*!.8685-964E@)+%0EH?!@40?8
@r1910
GGTTTAAACGTTCCGTCCCAGATACCGCTGTATNGCCGCGTCTGCGGGTTATAGTTCGACGGGACCTGCNGAATACGCCCGNGCAGATGATAATTACGGCTCACCTGCTGG
+
57-623A4A.*67)%'0H#@)'9F$+977D56&@9?8-?*EB69@<G8-#6!$7D'$AH'%FG>D7$9F*61=#"2EHD?A+'+%64"6+8*C10$BA>>'"!($/7-3H&
@r1911
CATAATNGNNTNCACCNCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCGCAACCTGACCACCGTCCNCTTCGT
+
(*)')#!#%!('!#))"(+'*$#%&'#!+#)!#$(%"!##%"*"#+&#+)((&())&"+&)"($)*&!"*$&'#)#&"$!$'#!('$**&
@r1912
NACGAAGTCCGTGAAGACGGAAACNAGTTTCTTGTTGTTCGCCAT
+
"'F">75>'(/GH2B%<G(D:67=?7E?E$"818A6)(#..(F"0
@r1913
CGGGGATTTATTTTATCTGAACTCGCTACGGTGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGT
+
+8B-(5/6(=-%A?-"!)/*H()0@D/C#>0-,?*5)B1<'E$<1+4E#06>8$-$5=%?E;"E<C:/36/>"206;)6$$3:/&?(=;/:!,75@=C-,H?06,"E
@r1914
TCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGAC
+
/9<%,.76,+!?E21;@9C'8C66D9>F8$H,16<%)G!E?2(F49DCH#3<+9!:0<
@r1915
GGTCGATTTGAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATNTCCTCACAGATAAAAAATCGCCCTCACACTGCAGGGCAA
+
?FC4H)>),98F<+'1+%9$)#!D*%84<)'004>8/85/"26;G#3)2:992AE(12E?-$)9.'<'H@0?GA8BE!$2,?A90$/521H-:C;7D59**F$D'-8+%)@1(41
@r1916
CGTCGCTGGCANCCTCCGNCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCNTCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCAT
+
":5%;'.GA$?F6C@+%5!!.+@5,H:$@@$A=13476H'%"07(<9<:?F$,+C:+FC'D2/>&D)EB58H?1/EA8&.F$657B,F4<B,46*)+C:-!#/+:?G>A?.?H??504"CG!8$)&'4H1--*4#DG))F=$<*%*G->=B(:EB/BD9E/)5.9B:'3
@r1917
GGGCCAGGGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGT
+
DA=##&<;6(94,@?*!"#A:%A(*)A?5/,9$194,G#6(;?!*G6D:#9-8@0'=9"HFG
@r1918
TAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCNANGG
+
6")'>5"-7%1((*$A?D=="'-4"%8H1;/:=5'D27&..'7>H=9G+0
@r1919
GTTTATGNTNGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGACCCTATCCAGTCGCANTTCCCCCAGGCACTGCGGGCNTTCTGAAAACTGANGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGTACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTC
+
!(&%&&#"$&+"%)"$))#()*%($#&$!!"($(+%!$#)%$$*%*'*($("+%&!)++#(#''(*#*")"!)%)*$('"$*%)$)&*"&%(&!$!"$#!$%)!'+**+#%%"#&#%'+"$#"'&$!('"")$($!'$(&#*!+')!!%'"%!!%"!%+($%*!(*'&)**$'"!'()!+$+$'+'#(#&(#!&%'"#%*+#!!#$++!"#$'%'##+)%)#(&"!))+%&(%!#"()!**#)#&)%"'$+#+"'(&+!+''
@r1920
ACGGTGTGACCGTCACGCTTTCTGAANTGTCAGCCCTGCAGCGCATTGAGTATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAG
+
;3%5?7/G@'70<$HG;C"'DBH5%.(?.)A3-#G*F:(C';!)-&:.&"2:F.<%!;8&)')F;*0@6.:9,.(C3G,B20;&<(%0+H"E+
@r1921
CATAAACATCCCTTACACTGGTGTGTTNAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGCTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGNGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTCACGNTCATACCGG
+
1C.!?G49:2)+2@H9"D;"6"A"$?C$E2.3@HF,EB-A?<727?-/413-)=!1H:2&.HD29'43$!3H/+D&A-/'+1B13F0>6?A?2<3+0://D.*@E8D-CC42E4+BC$*"*=:C.%H78#8+94D$,:)CC:&AA<2G1G5+*B<8G.=@%%5=,7E?'D;!9(-1-;E5&&
@r1922
GGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATC
+
=(+FC5+E2:!E'>9*38:3-&1?<G1*@8:A!D!":7-0-F83CA=C">-&1%9@H(H;F2-4"304>;01"D#".D?<:.G:)$85@A97()-,**++*<7$BFCB>4F.,!-9G':;&?006
@r1923
AAATNGCGAAGACNTGNCCNCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTANTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGC
+
!%*%!")'('&(("!)!'+"&#)++)#%&&!(%!+'$('))+!("*(&+()&)+*))&%''#!&+'%&"&))(+%"##'!!+#'*#!'#*%%)'&'+&)#)%"%'$&$$$*+#%+!%"(+&
@r1924
NNCANCTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGNTTCTGCGAACTTCAAAAAGCATC
+
$"*C.@:;@,?-!5'D4""E#A9#1/F/*$<9@/:E9=A.&9&A*%.&)*@/0<=&5;!0@7-4/-B
@r1925
ATNGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTNAGATAAACGGCAAC
+
))"+(")+")%"'$!!#'%$+))'##)*!*!#($#*)%&$$###%((($")#*#
@r1926
GTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGG
+
-=:-7,@5":8),%3(6@1-?;,30))1'18CA>5#3A$87+2+*!/G96E94E+!./%"81;-)G.&$;%)?05?/D?-08($&5:8?;2G628A7G"B@3DB6B7&3-,&<'AEE%*+3F&3HB!E2-AH9C@/>;00>=/;#605&?G4?<:+((;G4E8=2"$4;@+>3>!F*8&!@/<4><
@r1927
GGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAA
+
D,!5317.!C$;10=<5?)9?&6B,?F=1CA)51C1<"%$!'<7"E*<#F0(/<H6!!F&"B&@$E
@r1928
ANGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGT
+
%+(''"%'))&$%*)($$"((*&*!#$'!%)!!#$'*'!$')%)+"))+*$*)+'$')"(#"&*"#!&#%"(%%)(*#*"(!)%$!"*&&"(""%+'&&!"%()*("("$'+(&*!&"!%&(&)$!#%!+)"'%&)##
@r1929
NTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTC
+
!22#,3GCF<2:?*?1G@>F"7?8:/("!,@?6#+(62;,H%F?D<E8";'5H-CB-81#5,<>:26"<7B-/H'<&B*HA0C<$+':*45@+
@r1930
GTGTGCTTATTCTTGCCGACATGGGACTTGTTCAATGACANCTC
+
+#"'&!")())&$!$#*')!)!*(&)%!$"##(+!&%*"$#!+(
@r1931
AAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGG
+
A*(3:/-:,0*$2+/H**#..>A)38"2/F5%*+:%#(%BF1*82,?G@);)&><>B@>>)%+:@0BC0D3$@"6=2)9)(1
@r1932
ATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGNTCTATCGGATTTAGTNCGCTTTCTACGTTCGTGA
+
(4A,*+9*8E&C,6A9*-978&)%>BH50$)B,$<@?C=!:7"A2;87;4-H?,10+2?4G.+&;8%:EEE<+1)9#G7FE:H)"")2
@r1933
TGGTNTTATTCCCGATGCGTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAANCCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGT
+
<F:80>!)+?92*??&<*0C??)@@%%;@H;'CBA#G4D?+#EFF%96A3G+3/%@C7)>==,3-=;?0>$0F'#7F&6;G8,(F$F$4H@#-#HA5<2(?:H1&.6&
@r1934
ATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACNAGATTGAAACGATAAAAANGATAATGCAAACTACGGGNCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAA
+
*A(?3,815=G+?7@77;G(9;-<C<3DF2;F.0,6>H;*3@$#@;/A<$,(2!#H,%2'*!:9EB&#$.<7B45(6+7);/%=H"?6E$>#2B/&.71"!3E,.9=6GE)H6'EDG*+F8AG$(-><G@0;/
@r1935
CACGTGACGCGTCGATAAAATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCG
+
F(.4A<402?).=9>F(08B"%G8;/,9>G?:=9D7;G5,BC59@FE@71<21".55:>E:';(E>F:+&FDH1*%9+>9*3:5/-
@r1936
TTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACTATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTNCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGNTGAAGGGAANGAGTTTTNATCTGGCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAAT
+
:4@(*&)-8#H3C=)8(*"=455>(*A?7(6#*<>$=@'4;AG&G;?G50!*HEG=F!>5@/=*32H>9$A%%C@>)<'@'%)$>H+FD%4>2.!'/113-%/:28C=@12&)<8/6.D+(*5*@@AG8$HF*823089H"2476,<50/$.B02&:+&D&-,./H0<0*?F223(6!0$5$7?*AHE<E,*0'"7:%4>!'%12.>*3,>'%GC%$<<H%@*0=<F/:;.B9&/+B1D$901A##<04<C>=$5.7A5;E9=3FC07E*3C%24"($/H7>4A,A8HFH$E@2.2G
@r1937
ATCGCGNCNCCTTTNTNNCACGCCTGCTGCNCNAAAGNGCAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGC
+
%%)#*!)(#%**#)*#%*#&*$&%%$%%$#")$*))$%)%+#)''+'(!*+)#($!)%!)'#'(+"+")'$%$'*!+('!**++**+$+(*+!!$'!!''
@r1938
CTGAAATATACCGAAGAGGCGCAGAAGGCTTACGNACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAAC
+
12+'/D>;+'<-H.H&&?D*D1;4952'@9<")&=1')84@(0=+-.?,+H*.>41(&$/'&<>?,<8EA+#!>'9;,$7E?
@r1939
GACCGAGTTCAGAAATAAATAACGCGGAGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATC
+
88>;%5FF6!*-9F84)5HH3*F;)A<>HC,"%-"7!%=:B.-H@40&&46:A!"A'9+<6H/&*A%3BFD-%&(-D3%9F%1A*?2G/#&/#:
@r1940
CATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGGGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTAT
+
7,)"B-B5;",DB58%B3**-;2.908D80GC3&A:CC1@@!='":;&0.)/@%43"A5*HH,':*?0A?27%>13<);.D5!>'/FD7%#G17'@6,F$=7#;6F;1.@G">,7:8$G,37:
@r1941
NGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCGGGAATATGGTGCAGCAGC
+
"6C%D;%8='0HC-8EA*0?:/*:1<?*E1CE+*;+:8E3/)"B6:E2<4($-'E6;!5B""=E0B/<@%%@G<%AC
@r1942
GTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGT
+
-64?*B-$B*52"5B=9>G/:A7GH"1'1@(B+<<&C.$@
@r1943
ACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTTAGTGCGAAAGCGCCTGCAATGACCCCGCTGANGCTGGACA
+
/#,8,@-;H?9;2,E,=A*F<6DC4E,>$G)"D$E5A08<'E:2?1D!9846E51.!3+#@'24,:18%#H9,',3@1'8+<2<DFA//<27;>5&
@r1944
TGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGNATTCCTGTCATCCTT
+
+2G>'F3E<6#0<#;;:5!&@2.C%.?G0A?4$':%<+5!0(A7)A+28>?7"3:8'*3-+75A9;-1DF4)?,/#2!=+!E
@r1945
TNNCCNTGGTTCAGGCCGTGCNTTTGANATCNNCAAANCATAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATNGCGCTGT
+
)#&*)!&($*!&'*))*''!&&%)$))!''%)*%')'#$('&%+%*'#($&'#!$))'('!''+%**&&$)&!+#$%(+')'%$%*$#"$*"%&'+)+!%$!()('#*&$#)"*'*%"+!))*+#&)($$!'
@r1946
TACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCAT
+
#+*+&&)!#*#)+**'$'!'&'"$%'*&''(""+'%!&%'*"&*$'$%"!($!''&+*)(((+"+("$**%""+"%$$$"#%+
@r1947
NAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCC
+
.$BF)!)%=G8C$6482?1F#!2DH<#044-6)8*DF7626!-/>6-6GH;#5;-2*399G>G(&+17;C0>1F2/24<!+%/D
@r1948
CAGGCAGTTTGTTANATGGTGCCGGGAAGAAGCATNCGTTACCGCAGNACTNCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTG
+
)#'"++$#&))%!!%!#)+*'''&'"'+'"(""!)+&)!$"&(%+'+%$*%")%#("#("%""#($&#+')*&&'&+&%&#*##%&%!&#*')
@r1949
AGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACN
+
7/80&B%/2&%G7&;EBC#=C2>H$(9F2.8,&F7'.0+7D:#/75#<:G3>C"9'*+0,#$"E=&"5#-(@F2HD29B()+:GG"+EA/":&G#5/4G!"A
@r1950
CGCGAAGCTGGTNTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCG
+
@.!/5+G;F;'6B,09E;=/>H5>:?A1($;*=&C)&*:>#!.)40H,4:E##-C"=5AC
@r1951
TGTTNCNTAGCNGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATTAGTACGCNAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGA
+
(!*#!$%*"!%$'+*&%*%!$#+'!)$#'*")""#'+")&#(+(&&!%(!))')'&)%"(&''&(&%("))!#!($*'#$#"%!#")''!*"+($$&#&)()*%#(%(#&&#)%""#+*!'''&&!
@r1952
ANNCAGNAGTAGCACGCAGACTGAAATGTAGTCGCGGTANGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACNACGTTCTCATGGTTCATCNCGNATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGNGTAGTTGGCGATCTGCACGGATGNTACACGAAC
+
(&##%%!)&++($'*&$%(+)&%*"*$#+!%##$#+"$"&"#('#!"%*'%$#"'%'(+%)'($#&"(+#%)*+'""(*#(&&(')#(%%)'+!&'#(*)')%"#*('%(&$)!*"$+$$(("'%'()")&+*')*$*(%$"$%)()#++%($!"+"#'((%%)%$"%*+)*(&)*'(')!*&("$*!%($#$($$%!&)"&%(#%+*&!
@r1953
GCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAGAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGTCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCG
+
=+EA2*:AD)$1@).#072">1!EA=H$0.2H>38($B3F4G>+$FG&,1*-?"@G=&)EF*(G*!G(?>*9"B?&D:2(>6:.D-C8<+"D'2G7<A;'*.8<AHE:A?$+@D!D9=)60#0'/.(=D%$(&#-@:*ABC<4*=/D>5)?A:G"0:
@r1954
TTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTA
+
C:E'3)(A?A8/;4$!?B9(-=#$B,0*98=:3.F#=28$4,9,C&98"@
@r1955
GNAGNGCCNGCGTTCACGGTGATGGTCATACCACTGNCCGANACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGTCCACGGTCANCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGC
+
$''"#%((%%*(++!&#"+"*!&%$+%""'$(&+#)')*%$"!("*#($+'!*$&"++!!(%+&$!#)!'$&$"'"&'''&)"**)'$"(#""))&#(!+(+%()#(!+)+"!%$%)%+&%$+*%(+%+"#(*&"%#&*$*(*)"'$&%&&)%!'((!$%*"
@r1956
TTCCCGTTCATCNAGCAGTTCCAGCACAATCGATGGTGTTNCCAATTCATGGNAAAG
+
E6.=GH$6(145&$-H&%2*BFGG:87;<7E@9)10?%.0&@:/8>-*=-$B0#:."
@r1957
GAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTC
+
-2=,64/>+.*:1)30*HH3+G,@9A-**#A0*2=<D9F&9*>#:5=D=835"7C8B7A;"@E?G
@r1958
NGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTC
+
"4C$H:?>;H!G)H:6,-&'"."?<%/1"<:G-"/:!/HC7)HCD.=8D;D@6*#F%&9*EH7$+1BF2".$%0D,4@*-C#@32(A
@r1959
CAGCATTTTCACAAGCGTTATCTTTTACAAAACCGGTCTCACTCTCCTTTGATGCGAATGC
+
-!$*92013F&=74$$#?8564DB68(0;@35D5@G6/3ED2F7H=!1/8-3B9!D?#C)A
@r1960
AANTGNNANNNNCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACGGATGTCAAACANCAAAAA
+
)&!)!)"($!%"+)+#&%!#(*&$*+)*%*'''#)$()&(()%+!$++%+%)'$(""!%#)"'%")+)'&"+*!
@r1961
NCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTC
+
"34#(C/04%BE985/@C7CC9F71%>C-*7+"?/+-D4/&<
@r1962
NTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGA
+
$>*4B87%8).E+#F$$5;A(A-)">12,*H;2-&B21A<
@r1963
CTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGA
+
.0<A6D'E?,!".-@"6'35!='@B%$DG5DB#D/E83?'F."#(.4#"+E%-*))#=A84#D%C@H;A
@r1964
AGTCAACTCCCTNAAATGTTTTTTTCCTTANGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTNTTAAACATA
+
<';/,-DBB-;"4*<'(@=#A(/#A3H+<:#<2!9G-+6-=!D?,H>@33'/E-3C0;-3"@%@'?52D/1F8"4&.)"E+=/21>)G
@r1965
NGTNAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCAC
+
))(!%+$(%)##&*#&''""%)&+)#'&!$$#"*&)"*+#%+*&*!"!#$''*
@r1966
TCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATNAC
+
?)$2,,1%:*4-@A(<7EC)&/0?$3418>B:3A5>85;)<G5%&;AF"$HD<2"D'*#CA
@r1967
CTTNNCTCCCGAAGTCGAAATCAANCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGNCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGA
+
))&#"+**!)(**+#)$#**)!)$#*%)&*)$)#&!'*(#**&$)%)&'"**!#+)#"#($((!+)""'!*"&&"$"!%*!!!'()$%)'(*$()$&&
@r1968
CCGGGCCTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGNTTTTCCGCGCCAGCGTGAAAGCAGTGTG
+
09-AA>9=#'2B*42E#HG.8=<D&2@/>*>::%18&)@*+6G325G82$0?--E6!(4.:$(+(&#2:21-(???.>B+D9?)B5+!/#<:+*/70>E?">+#1,!AD7F6=="57#"F.'C4#;1=
@r1969
CGCCGNCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTNCGAA
+
@1?86!.!>B-@@5-7:4"C'$8-:2G"09*BA('=9;<.:&D+"#H(2%?):;).*%0BB"A?>G3'(G$4101.7B4D0@?$3!9)@F""#4=><!;:B5%F/%1$:2>,!G"C"3@G1-CD7,0D/,(H4)8636)F7<B:H!1D!,5<
@r1970
GATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGNCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCT
+
C,F(++B?1E9<F"*:;%?E?!"5F=$0*<$@/H)F(F1-3:+3?,:<E7#<+>+%)"H</?%85C**-E-C!%?(F?1.%-/*.;;371#.GB>+-%<,")'>%7A,@C9+F&E#5705151FEG,E$A)2H/C;)2<2D2?!;00
@r1971
GTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCC
+
,2;.5@&58?0H'90@"0.2/>%=G?-G:=0"D2/F6!9=1'H.5<*.*12E<68
@r1972
GATCAAACACTTATGGCTATCCAGACTAAATTCACTATAGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCT
+
FG.6!"7<F+F94H@C'=;%668/1%/&G1#>9%",2C-2)5".5:%6002544B'&D,#0@=93H/:!#;)+F(G.<+5:9.>7#5=HH9DH.9(7(CDA";?7?32%>=1)/G6/"3#.7.>=?8='&6A=.4+AEH/'$D;@3&
@r1973
TTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTA
+
5):7)<,H'F:4%'E6"#2=4#$2((%$94G?F@1=&&"&=1+$.>,)
@r1974
TGGNCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCNTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGAAGAGATCGTGCCGGAGTTCATCGAAAAAATG
+
@A?5=!#F#G+(.,C;&3/(0GH%#;-5)<3F@=@%7/'=E=?%A+>.++5,36%9+#3=H:)-!)6C!)7&<#2!?3*6-D&H.&F35HA@D)CB,1DD11=/7@477&'7;:45.8G-,2:0*09#''F)D=/5.>9"7-;=,-?(4('AA$:D/#:)&C82G%-
@r1975
CCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCA
+
/4&A06=#E3/#@8357%9=(.D.1C29F6A6#+C=-4A"C;G%0/="*C<@BA7),5$3#6+AG7)?<!D).+,;"C$7F(.*&0*E#F5=6&%>*1G7%.&!F;2'C(3G#$,?0F>5:50':118F'GB<7B!8?:6,D;?@15$9,8"E7G,'@2";'D'?)D#?;D+(@,6;<1=$,GFC@>"&86@F*"8#$<(
@r1976
CAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGC
+
DB$41%FA/-8F?*7<"B+D%$#EB8-->(+:=1'F/A"+!9B1)0(9(4
@r1977
GCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGANAGCGTCAGAG
+
(,(:-.C(F-!2C$E'!477E(5%E1>0)0<9@'77,@@D55.:4"H7,3@(F<;-2F?A35:*<0%+E?9?GD+-%',9==BABH;
@r1978
CGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAG
+
53#5&9C&)4E?*E;'!@C+92%FF1)9#5,C<F!G5;"7:%H.E2""
@r1979
GCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGA
+
6&CC2F+)@25BC@C,?A)(H1!+2C;:;GB(BC$,(2G=@72=G46(9-.H4F#
@r1980
ACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCACCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACGCCGTGAGTTACC
+
06BC<E0A/.4<F?<6$-"(G(="2-#9#+2+,7C#)@&&+7*$7;H>(+&E?BH2H>)+),&/D.(C-#&!0;56.#,.A43#:5*&%.@!>CCH*><(.*.(=;..CCD@+#B7@=6&4+-%7(*5H/C0"$G&-?$
@r1981
NCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCC
+
!7:2@31;AF;3-.$"3H,8/FG97$%$1=/##F(>;"7A95+4'-*,=E/&';2;$,3GF#/:35D*HF$5/H#%0@F'(9E4@BB)F"!='8E0EB:/?@A36))%98<<E>-D(;=5*/2%+6<3?<5+-@4G"F/9;70B&0756
@r1982
AATACNGTGATGACGATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATNAACCGAAGCGGCTAAAGCCAAAGCCTGGAATNAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGC
+
(@>D9'!.7"%08.3<2-D.%!@(%&@:?&*7C1*/."<'8HBF$=)G73!$1.#)1)$BC"D4>03&5H-@@!$/)?*0%!*6*<8,%3EH0$C>A@1599:&95"G*E@)A=@:4<G<*;D;FC7GG&=GG',-+'8=:6
@r1983
TNATGCGGAAATACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGGGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCGCAGAACTCAAA
+
%#%+!'"%"%'%#$$"%"#"!)#&()()+&%+%)+**#'!&&&###'%+!#*''!(##%&*'!+'""+#$##+$)#!%*%'''&"%*$%"%#(*&!%""&('&)((**!&"!'&&%$'#)+(%"#("#!'(%(&)"'#&#!+!+*##$!&(#'&("('(*
@r1984
ATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCT
+
>;H1&1>=B)?)5=(E-HG1-=7?864'(.6CG:5?@70E<,-9DD7*1!D.5B.%2(6C";)C!+-*,%#=E2.G4HF(920B82.9293
@r1985
AGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAANCACAAGCCTCTGACAGCGAGAATCAACAGTNATANTTCCGTTACGTTACATTCATGGCTTGATNGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAA
+
>02437/B$3<>1A$2%'-"/",(?>4AD&*#/+#9(C)0"57"B*GC8D5-(3??-1(&,;-5(=+97">=A(-D$.&@+B!"*,+(,%$-.(%48)%$*36;%;9H):2)!E!8-4@0<6"3(2E.HB(.'8.D-7F.@?<0
@r1986
ATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTNCTGAGGTCATTACTGG
+
A4<"%,'716!;;&-1(!,$6H6B+>?28#4F"2,A>0B+3HC*AB53B)F&1CE@&(G:$!14D@:*
@r1987
NTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTA
+
!?864E"!C0"%HH3(#D95H'>D=9>+>%%"(A&-/,5&>B"<B<+*G
@r1988
GGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTAT
+
>C46@#A8-9/0A+2&AC:'4A+=-<=B-*<2)<(3#'D$'<*'.ED<-=28!FH<')@.7@,F)%:0F!$CB%'?G69:6C*/F!+42'&7+<!4+!9G.D4;6,B2#;(C785C.&:4E&,=#?+H'F:;=E>)*=,+&+
@r1989
GTCAGGAGCAGCGGGAAAGGCTGACCNGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGG
+
B/F$+:@7!.9E=E9.A2G@6="C0&-(&C8!=$:07>.C'.,#4'.</:30.G3>1":4&&A!(8#D(>$&G&/!)EF<!$
@r1990
GAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAA
+
>0?4&/F-+6,H;@#C*<>A;D@(HD.5CF*/=F<-BG>H6@,2+;4,=":)HH?>8/)7<E7!H5*%F?83''!2(9,
@r1991
TTTATCCCTCGTTTTACGGGATTTTCCCTCGTTTTGAGGGATGCACCATTC
+
3)383&?EHEEGC"6E2#D@#!;<8.-"?H%@6$A:&)A&#)H98E3B--?
@r1992
AAGATAGCAGTGATGTCAAACGACGNAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGNAGCGGAAGTTAACACTTATGAAA
+
/,)?@>:1,!(%9?<*;7.."@=F$->G(;0?@FE,(&&"!5*,#G92G,>H!G8@B4:>44;:B+H6"#"'5*($A:E"$#;#DC"3/.+4>;2/*,%%'DCD/$%$:-56=1C+!;#(60F#9*@"DA>?#:C0*
@r1993
NTNNTGAATACGGTCANACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATANTGACTTATTGAATA
+
!%$$*+))"+'**(###)!!$(&+##*')*(+))%*&!##$*"(%**&!$%"$""$"")*$%"$*!+%#%#$+))"!")"*
@r1994
CCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGNCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCNAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTACCCGACGGAAATCCCCGCT
+
<9,D=3A)/E@!974;@,&&F.AH;*2947<6B=HD7C/FD$G*+F%<3%1@!+&GFC?08(/),*%A1076-9&(8A$A'$%+>':;F)2B5=<&0#4HF'<784'4.A<3:1.97<0C-008')8&G83A;B#!FB0A#GE$(6=2*:@+4G281$>F5;A5:;:=!5?$49/;*87;>B4!*'2C2?474*)<-'#F#5
@r1995
TTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCG
+
38:"8(9%9E'G)F+(?4.H79&9%-A).C5*6;$3!+=B6!=BH>)19$$A"1F(2A"-,/B:E(H/D)B7D!-$-F6B'<"
@r1996
AAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAA
+
+$!%!*&%!%#(+"&$(#')$))+!&&$*((($#%'!"$*'))+&#!!(!(*"&%%*"+*%&+#!'+!
@r1997
GGCAGTCAGGCTGTCGCCGGACACCGCATNCGTCAGGCTGCTGATCCCATGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCG
+
B,$057*-G/$H=6!$@HG#&4H>E&7$BCG/98E-D7/+@636"#D*;,DE#F!6:6)#D3*5"=&:GG6?(!4=(5+F1'-/7<3H;#6
@r1998
NGNATTTTGNGNNGGNTNAGAAATGGNGATAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTT
+
#((!%#%!($(*")*!%$')($&('(%#&#+%)#$#%')*!*+"(&&!!("*+#*)&#$)+!""%+'$"!#*'*%+$!+)**!(+)&%!%+''$*#(+!#"&+*"%#$%"!&(*#$'&+#%$%&)$
@r1999
ACCCTTGCCACCGCCTGGCAGATCGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTNCCATTGTTCATTCCACGGACAAAAACAGAGAAAG
+
G6):F#,)!98G2?A).?,G<(2AH)<7DDC.(-<!00?1$G@@9$/%&6EE&-7:.0>@5%#6)872''&<*!+>2+).BB+'E<)F3-1>-7(971'B/=FH(*(#A(,05(8%-FH,'+>2,$AD'G>)(36+)/
@r2000
TACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCCCATTGCAGAATGGGGATTTGTCTTCATTAGACTCATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCGTCTACATAAACACCTNCGTGATGTCTGCATGGAGACAAGCCACCGGATNTGCACAACANNGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAANCAGTAAGATAATACTCAACCCG
+
?A"#'1&AB7(%E)20$;H2E<.@?&!H82(0%G4%#.7H#4>)0?6*#".6F+.18!B!$=G7,C'8&(96/#C-:4,21!<+-&(B;9(5$-B,@)H21>#GG%-,'+%:0HA"6?:&BC&??%7-/>F?3((E!C*&3E#?"+25*@*:DD&0<;!(>G,6/?4<51HF,@>>?'2%F$1AA46"5(2&3CA6.6H",C>8B@)&4((B*@H>=><7H0?&$537276H8$C,G;A03<8B;,07..;E-D*C?CFC"+<;'%5)5F;B-+1&(7/<6E8::-G7)+D$%*5-<&4A.'71"%0,/(%F&H6%D$#E
@r2001
GGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACAC
+
D-3&E'84$,GE5=-G-8&C)1<&!G68>#%;3%>024%07!
@r2002
GAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGTGACAGACTGCGNGTTGGCTCTGTCACAGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATCAGTCAAC
+
*;G?233H907-8;..5C$D><12(73%&>!68@D:0"9H3)D7++!.&@:5DH>85.>":A,H3&EH&%98B<7$::&.%6&;A8%?!5C9),5/H@G!E?$+$+19#6%CG>05/:>
@r2003
CAGCCGGACTTCAGGCCTGCCATCCAGTTCCNGCGAAGCTGGTCTTCCGCCGCCCAG
+
?2+,,&B2A1)E-%"H07>.%CGG9938)?D6.9;!C?7=,'+%>@/3B$(<G8>5C
@r2004
NGATNCCNNCNNNGTCTCNCNTNCCGNGCTGGAGACAGCNGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCTGACAGTACGTGGAAAACGGCGTCAAAANGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGAATGCGGACGCACAGCGCGAAGGCATTAANGCCTCNGCCCGTTACCCG
+
'!(%"%#"%#!'"$!$$(!!!"#'*'"'&$&%+#(%+!'&!)+)"+#''*)$'+)"#&*#"&'"'%&)!$(()#+$!)!+)(+("("!%**")$%!($"*%(#(+&#&*&$"$"$%#&*!*##%*')%&'(&$%##"(##+)'+!$!**("%*#("""#%'#)'*'#&$%))#%)**!")"("!%''$*##'$$+#(!"++*(&(*(*"!+!##!((%$"+*+$"(+)**"+$&%"!!%!"(*&&$%#)')%#++!$&''&&
@r2005
NAACTGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGA
+
%>-."""**319!+&(!8E0.1:;'&G=6FDF45A#7=&3)3.*<%%C#>##:9
@r2006
CNGNACAGAATGAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAA
+
*&'%'*%*$*%(+'&%)#&%&)*"+&'(%"'&%+%)&"*()$$+()$+$%+"(+!'*"
@r2007
TCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTNTCCATTGAGCATTGCCGCAATTTCTTT
+
5D12,C9&&&#$?)2">.0+?)):$F&</0&>,+5(.&6GA''7&35AB'>:,=8%":928=@9#7'/*77BH?.BB<>
@r2008
GTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATG
+
2469$%?2258.9=2B-.,:7F':C:1$G6H.-3<,6%3H#<E*3EAC3'!1(>,8"E#'
@r2009
TATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACA
+
@*H@2/==F)()="!3)&%,..GE:F;):?-8+)&(1D?*F.H5%5B"<%($!&#&G4'5FE;.@%/
@r2010
CAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAACGAGTACTG
+
0('?#H"4++'73@64A>'.11>C!E0+A&!/!810#=AF$B)5%/7.(2")@!247D=CHA5&<?5$'219<F0*9DA4%&H
@r2011
ACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAA
+
=5(5&<?EA@,:0%56/,=!2'@;F;8*<@<BH<5/;?6<?@6G7BB,,-+)&#$G<!<8=,E6$31%&-
@r2012
NATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCANAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGNCATTCTCATGGTTCATCGCGG
+
,G-?D)?HA!)&#-A-8:&/"'(:F>7,A>*A6C(A'=,+B*4,465;=E.<4'3-0)A%4D?14<E1+'D?$C-"A*-G'C'64B/AC"+4(AB55-H9>%),.,2B'';10C'&2-0
@r2013
CGGATACCGCGAAAGAGCAGATTTATAACCGCTACATACTACGCCGGAAG
+
DGA7!?,;'(.-9%($@C%(971:<6,83#:$54)=;4A$@2."F'0C<F
@r2014
GNGGTGGGTGNTGCNAANTNAANCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATN
+
$"%'$*"()(#*%&!*%$"")'!+'%)#+#'$$+$#*+&#'#!(!(+#$('&)#!%)(%!$##"*&$&$
@r2015
TCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTNTTATCCCGGATGGGAGTAAGCGTATTGCTA
+
C713*<!"/=63F@),E*#<.*#H)56G>F1=(,!;F>!G$/H$(.%G$,@-!%79B+7@17C=)-,
@r2016
AATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAAT
+
>##@/=D2&=0B;A#8/).>GH(+/B+F9*)F0759C.&3B
@r2017
CCGCAGAGAAGTTCCCCGTCAGTGCTGTGGACATAGTTAATNCGGGAA
+
=,@BC/&1E?19;'DC75H?3GG&#)9GC40/>'71#%!;;;C*%040
@r2018
CGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGT
+
8<93$39;:14""%(H7H=7$&2C,<E@53&;=:H(>D70A"7=-E?E5F&(F?
@r2019
ANGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGG
+
#,>7;'..B.*1B$65!<FB)9>*#)"30GB072&=<"!&-#D3#7/CB@2D
@r2020
CTCTGCNTCCGNTGTGGNGGTTGNCAATGTAGATTAANCCNTCGTGNTNCNGACCACAGACCC
+
'(#)'*!$#'%!"($(*"*(#!)")''(#*&)!%&'#%$(%**(&%""&'+)&$(%"#%()++
@r2021
TGCTTGTTACGGTTGATTTCGANTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGC
+
G4!C7ED@,3$DC">%('2<65>66*6C.C?&&$49.-87B</1F37D(@D?G5/@G;.'8'(.(0H?6F=(.253B);ED(#=1)91
@r2022
CATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCG
+
:6G512*9,E2$EAE)"1;@0F&G:7A4B54"7-<%+,"%2FCH4CE,7A'G3BB</6/)F"3(F/$"=3&-7=3*G%10)=A<B/)>)7&?187>(7.7EA104
@r2023
NNANCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAAGGGAAANAGTTACGCCGATCCGGAGCAGAAGGTGATCAACCGCTGGC
+
'&$!+***))*&*!+%)()""!%%&'*+''("!&)"&%(+%*"#$%)!'$"*$#+*%*!""'!$##(('*&%)(&$*##'%&#"(!%&)+!+'+%"&&%!!")'%)('''$'&#
@r2024
CCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGC
+
G'F8H*)F;FA%3+<=+=:6<,':*825+!HCH18;:40C:)E2E5C?/8$
@r2025
GTATATCGCTGCCGGACTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCC
+
*?36??3*,!=9.3+<6$=#:+BH+6(#=75+FA1:.#>@*"6"7$)G;+-BF7*#B<F2%E"-.6D(!D)975':.:+-B@;H#H-A91243G27<!G9*7($;81G((031#?*?-.FHH@?0-"+@<%4/829H:='00FE;5<."59-&6G?=>&AFC)#8&)/!)),1%%/'1A6!$$&;?:H
@r2026
GTAAAAGATTACTCCATAAGCAAGTTGTCATTTAGCATGATACAATANACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAG
+
!=&?(3EC,52).4&;>,;)9(3/!FG7F-;5(5.4">.*1%@=&H"D"/8A2.3C)"6(#C/A>1D#4EFB347:7F8:;6F%0'%'9=A:E.G+/(88'.E/>E#5GH62@?D@/.52**3
@r2027
ATTTCAGCATCCCTTTCGGCATACCATTTTATGACAGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGTAGAACGGGCATTCCCTGTTNCTGCCAGTTNTGAATGGTACGGATACTCGCACCGAGAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAAT
+
<3D@.2<H8EA;"$?1:F8<*C21&!*-*5D0;635+<(DB*F/@:&)BD'*E-<85:#@!D:)%*2F/<@.$5&CAE-*.EC&/5C00$+E'@%>C?2%1A/DB!5+.)E#?&&)*/"3/+!,69@?315@821A%&;<,/'2/DFH<DCC)H-EHC*-3>G5G8$&(C$84H'A<)!6!BD)"CB,/H+@?$)=7"=1$#4!8/4C):07+$,2%/G14=&37$%23@(&':?%*""2(387$<(C.C>14:'E)1F57&G#-*G4=A,'
@r2028
TCCCGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTG
+
'7?2(##7;7->/>8-$;B6?B''.?H**)4&.A+6!$)462.6G(?,3,A88,?/C?:HA=<B,4=0?!:"!91$@#EB8?<:2'E<3&)C%F40E87(==@B9-)">5>0DF8H95F3@A"E2!&@2)$9@,D,2*$(+A+"74H/";B7;G98":E'@:2,#FC-!G.A2:&62:9,'A-"B*
@r2029
NTCNNGCAGCCGCAGCACGTTCCTGCATANGACGTGTCTGCCGCTCTACCATATNTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATG
+
!%'!!#*+"!+(%%''$!*)!!)+$"*)$*$'"'('"++('%'"(#$++#$$$&!"*"($!"*+&(#+!*"")'!)+!($!+$#%%#++'+($'##(""")+*#(!#$$*$"
@r2030
GCGTGGACAGTACAAAGGAGGNACTCACCGCGCTCAGTTCGCTGCACTGTT
+
,*/#91+-E2*.@'*,H!F+;./7@7/0*?""AF.5+F$EB&'C#(%5)3>
@r2031
NAANAAAATCCATCGCTGANTGCGTATCCAGCTCACTCTCANTAGTGGCG
+
&)%!&%*'+)"*+!*)&"$"(+%#(%"*+!'#'&&*%)")"&+'''&$''
@r2032
NTNNCNNNTNACTGGCTGAACACACCGTTGATGATCTGCGATACCTGCTGTACCTGCGGNTNTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGA
+
!&!*'#$"!"'(+)*)*(#&(*+((%$$*$*&"!#%#*!(+*""!$&#&"&$$'""(%%&+&#(+)(""&#"%()!+)""$+$"($"*"+""%+%(**&
@r2033
CAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAAT
+
+.>,A&/87(*A%::!>B.-4-G&G>3!4*3C;"*;++40H%3B5#;C
@r2034
AGCNAGATGCCGGTCATACCNCCGGCCCNAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGGGGCAGCCCCCAGGACAATCTG
+
!"&+"*(+$"(+*&%"#(+(&!&++"*'+#)$(%#))!'"+&%'#'"##+%#'+'&++#)"&''"&*!!+*+(#)"('*$(#'#+&&'&(+'(%((#*(""+$&$('#)&
@r2035
AAAGANGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAAAATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCNGAACCAGACT
+
-"5#=HG.?$<0!AAF$D$A*D..&5$:2;"3)F8>G#*)>&@9*G0%)2$:D=)=*2-:-@$!7AF'**+CC,;$,%2B0*?,4<A,844"
@r2036
CAATNNAGCCGCTNTCNCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTG
+
&'$'%'**$&$$#%()'#+"%$"$"$(')("+"+"#(&&#!+)*!%!!!(%$&"!$$#$#$'#(+&))(#+*&#*"$&
@r2037
GGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATC
+
&7G8!<D$7)0.!6*B7E0?C)6D1".A!8:;G/;!C*9&8:@9*?6>AG5-A">H5""57)(;&,#*@/4-5*(<A/C4/%,4:1*!1&"EA3=?802H?9;9G/"C23:C.*-22;64:
@r2038
TGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGA
+
85#,C0=+>?$.":%E',>'@0-E*8#$>FE>+#D6(FAD4*
@r2039
GCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGNGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTNANGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGC
+
/E$";4362%=@3'-$08D#E!C+"0G:;2=#F$B69)?F351)92#37</8+5(1+47A3G#G&/+%41(41A-!HH/B.7-6*BFE7A#/A<F293<FGD+5.=5C3#<2%EAB+-1HA78,(D"F&C'8',6A:D3G$(2C#)9!:(5D<%F+>'#)0H8<B%8G:H*90HF,*4>'"=4&#4+19'7+7D@?5+
@r2040
AGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCC
+
146C)1-.+7/G9:%#67"?7$$3BFG%<$7!#2-0!;3*03.A45(%2(;"A'@-A,5<(<F9>,16DD*9'0#<)
@r2041
CGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATGAGCCTGGTAGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACNGACGGCGTGA
+
+GA1E8*%(#./1F1C8F>:06*(!1(*54&1(-4/(?)7%"8%C-).=$:&HC:7#?!5;%%"-(?53%!"E7,C!0,DFD.AACG:,3!><%5$$DF2?+B/&4F
@r2042
TCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCANGAGCACCGATAACAACCGGATGCTGGT
+
A:0(1:8#@8%,2C;?*3F02FD7C/$98!H?095=7.6$,C/&E)%0/-A7?'.G9G;D.9G+6A2"=&:,*=0*;"G%8:86AH0(51;3(2
@r2043
NAAGCATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGNCCGTCGGA
+
%)!*"+'"'&&$)(%##$"'(%$*&$#+&)*+%!*((!*'####+"!++%
@r2044
CCGGGATGGCGGAAGGTATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGGTGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATT
+
72@/!)$!D$*8G#".:#B;&82AG.($4'=DC8.!6!8G)65F816FH1E',316/@*24@.D2@@1(/G2:7!6%'D+;?DA2BAH8&>7&#,<3B%9G!=/ED?-8B2&9&#C*6*06>B0,((<=:@!=*#>(-3"0.F?3!
@r2045
GCGACTTNTCAACGCCCTCAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTANAGCCTCTTTGCGTTTGTTTGCACGAACCATATCTAAGTATTTCCTTAGNTAACAATTGATTGAATGTATGCAAATAA
+
"EC+:1';1!F$$#?##5B'$28=-C$).#5G=9522.(=/AAH-,@?#33>E?A%&7"63*76@)/"*&B0+2,5GB!?A'<0:G>,=,6?,'HC7D*09C?(<GE+F909"2-?'?8/;3G30:*(H6E))>,;.@2!>=/*8/111B!BD2-#B;1H10
@r2046
TGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCNGATCGNCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTG
+
C<"*""*/;00(%4-D7#;&H4(91&896A:77:85!-"G"*:G./(D:+'<+B2"",&28$<5)*80>%'D-"/4E.'7,<D51E?4;.&*&"$4D+?8/1=FH@!984C@.#&7/#A$=A'F>7E&07>"D+:FHH$84=?068'8=.D@'G,,*'F!4/7(:74><-
@r2047
CTGTATTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGG
+
6!8H:*%>=.1=7C/<>@//>,F,914$&,F,++%$>=CCFB#5=@2-"4C
@r2048
AGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGNGGCACGGTGAATGGTGTCACGCC
+
6)4C/G%G.(H@7$$!2>,?EA'31"4%%3#5F-:4"0<''$9(<E'A*E1FH%9;*;111A?"CF>%3
@r2049
CACNTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCNTCCGTCGCCTGCCGGNTGAAGATCCGCAGNATCTGGCGGACCCGGCTTACCGCCGCCGTCGC
+
(&')+#+$)&%$$%)&+"+"+('"&!"$!%**'&(+)))!'+")!%(')")%%($$'"%(&$*)"$+)!)$)'&#%$%+**$*!$*'%*+&"*##&)%$"&%*&$!'!$"''')($+'!+"$"(
@r2050
CACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTATTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGNCAGCGACGTCCAAGAAGCCTTGAAACA
+
/)7$EF?'.??,9C1,A4@?G"F-</,=!!47!@.02"D4,;6D@"/%-E3&%G;C+&%&;D:+,-#G59/%1@;D1'#)=/G!?1=*A&6;=2>@)@A'A)1@C/#.??!8;;F!)/-&-5>'+>)=/H'5":3*<+;;A,@A!4#")#G)2H@?"=#=+C/2<??+.)8,07&E?B9?+F)
@r2051
NNCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTG
+
*!9+$@@@&-G=&)@39@--@A1E=?2:*#%$+*//A,8+6HE.91;;;9<)!/A,1D9&?379@A=/D@A<2A(+
@r2052
ATTCTTCATAATTCAATCCATTTANTATGTTATGTTCTGAGGGGAGTGA
+
<F1B8.=#7<);=9:.3EA6(C5C+:+);)H5D%7@$@##@GF;?#>D$
@r2053
GGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCAT
+
2,?8C(=9%;9A.8;&:1*D1:83$EB071.&D$B%('4G$.'(<#@4+
@r2054
TGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTNTT
+
&)#+)$*$&)#"!%)*%!(!%#"&&$&$$$+)+*((&*#"$)%(+(!)"!*+!!+''$*!+*#!"$(
@r2055
GTCNNNGANGNNNANATGAGNNNAANAGGNTACCANNGGNTNNCNTAANNNANNANNNNNNGNANNNNAGNTTNNTCNATNANGATAGGGNANCNTNCAANTNAGNCNTNTGA
+
#"$#!#!"!$!$!"!"$"#""!!"$!!#"$$#"##"!"""##""!$#$$!!#"#""""!"$#$$##!"#$#"#$!$$!""#"""#"#$!!$"""$"!$!#!"#"!!$!"!!!$
@r2056
AACGAATCAGCAACTCACAAAACGGGATCGTNAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATCTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAAGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCC
+
+)$&*')$*)$*""#"$&))"#$%!(&(*'*+()!#*!%&)('&&&!(#*&'#%$"%"!)&%#(**("!('+'*!"(&*''$+%&!+!#$$'%)'!&"')%$&*%'"*+#!(*+)**+$)!%'"+)$#++"%$#+!)+!&!)$#"'#'')#&&&&+!!(*!$!"#%+%(!"(+"&%##*+%%(#*#*(+%$$&$**!&&)%&)*%&+&$"+(!#*%'&+$#"#+*$+#'"+'$'+##")))#%(")'$")"*$(!++#!%&%"$+
@r2057
TTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGG
+
4F.@/8<8*>8;0)D+',A@9G!H*==5?7/5)/4F.5B@$8=>9D(1D.#3;+FE*D((,BGG")G3%,9(';#/!+<-/5!H4D>$$+:A.C,$'/A0:C%3:(5,"E)AH>:)B9'+G*<?0:#!)*)-H%0B@&5$8?227$GD*/$#(!252!8)*C%=$7)B?1/;5:)@
@r2058
NCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGNAAATCCCCGTAAAGGCAGATNCGCGCCATGGCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTGGNTTGCTNAGTTGTTCAGGAATATGGTGNAGCAGCTCGCTGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACNGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAGTCATCCTCACGATGAAAGTCCGGCATNTCAATCCCCGCCA
+
&+$:G0A/E-%4-:ACEC$?=..)9#4!?A=-(/+,GF/50H)<B8>$60D:?$"-,==*#:*'8"0%.#?&%&!2D#.2F,?"C.F*>%C.4"?>7>$=.1=1(<,F27&;03B8#*,>4H:7(FA>79.@9>"@=D&A"#*<#"31<&:=4D6!5>2$*5$G=C),AC/#>19F'7H%'*9=.><"*.*=@7=./"?5"D=8C<2@8EC;!!>*(/24'0=;!+-7'?9FD;&9/?')=&*'3/84A$5'2F;3B89@)HEG:E?F/C<691)>&*3-2*D(+,E&<0<"(E#&)-FH$*5):23#8/@1A@$7)/'*#74:*"+&7;B7AB9?0'0#A-"=FC09#'G4(C!B0"&#!,.44+6AC'?/65#&#5
@r2059
ACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTNTACTGCACCTGGGCCATGTAAGCTGACTT
+
>7=-7;*E,A#"D<-/%DE%3EF'#!@2$=#"F?F#4*+>>D<=3E(014@8'/4(,G@A./6/,EF.'4@F,0CG@G0;<?,(%-+F-1A%5FB38#!0&8H4+..$'#CA%B1/A6&%D.E9#(:%$C=(F;GF7;C'%166
@r2060
NAAGATNTTTCCCCTGCGTTAATNTCTCCGGTGAGCCGGAGGCTATTTCCGAATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCAACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGTTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGNTTCATAAGTNCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTG
+
#&*&)*#)+%%#)*!'%%*#&&+&!)$#!"+#!*$)')"!$)'$)#$%!+%"+')%$(++'&%%'"$&!$)%)+("#)'*')$%##!%$(&&&(('!#)*+&$#!$"#$&(*#(#"&'(+$"#+'**#+&!*)!)(++)"'&!*($%!*#!#(%"+"!%""''*!$(!#"*%"($!#)!*"+%%#%!!(")#*(+)"$))'$)'#!("+')''$'#*)+!$)+%'+)*)((($$(#*"($+)')*"!$##+*!"!)+$+&
@r2061
NGGCCGTGATNACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGCGGGAATGGTGGGCGTTTTCNTACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCA
+
&+/0>'FB)+A;.2F57D,E>+3.,09'9)'G)'BH*C2?!-9)A<(D!+-34?C*%>(-D&;G,"=1-*D;F4!G(CC-?')="<4B8E-3@FE2F*,4@E.B19"##*<1-/:)@
@r2062
NGGGNNCTTNTCAAGTGAAACCGGGTACATTGCCGTCGTTGNCGGGCGGGGATAC
+
!)*($'"%)#+)"*"&+$%%%)*&##$*!$*$%)'!%*!!)*($$&("!""")$#
@r2063
CGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGGATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTATTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGNTAAAATTTTCCGGTAACGGACCGAGNTCAGAAATAAATAACGCGGCGCCGGAAGCCACGGCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCNCGATGCCTCATCACTGTGGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCA
+
;G?8&@F.&7D#'(<,00)A!9+)#6D73%376+/.#4&H2&CB3EF5!7<'735H,E(,.>9?G,1$2;AEA>69$)10(FH2=!%BF)<7-(;17)1&*C'A1<*,%G;:(3$?1;=6*H.%$36>,%".FG?.?-CB9"#8/4<98<E!=!(F*1EC*%7A7(>221#/0HE<:58"H?B;0;&A6<H-8=@F>3.71(@/3$1H&/=.../2@2;31+439GBDB=0#/#*E$;(F<55ADD*@*/:D"-%F#H98+1E2;!H#98;(0EDB"ED.()4$9@6B>.&'0$5G1@@,:#D>EE7#.&*.8E)'(/=F':.DE)-A"7/'.>*$&@(HE(!H+;;>>E6C6GH;"G1A!:H?BF86)*17<3,/=$?;A5+GD?G=;/A;'/D@=+2B%8%(5?
@r2064
ACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGNCTGAATTACTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGA
+
C:B<"FG$=H,&-#-@>9+"60F6*4:1*9C/D1:@&="%!)5DF1=;=<!3H(8,2B.;5((6DH6>.FBD+3'8:?,A/8+!=:1=:!"2=:D7"G>*F=AE"1;:D;F6)5!@B@0C.'E+@H(<4"H44A"G;4@/E./$8!=<$%E/"-=#A8/=82B:4):1CF618!9E)*-$5(8<;2/,);7#2&(!0!
@r2065
GATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCAC
+
&##=?%?B'F&.87,G$'84G<!4*9B+D#'?$,(.=D0G#*1,#+"65".=)?-8!C
@r2066
ATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGACTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGT
+
GC6HE$>E!';#6!)"2#+,'3B.'4,B/+E6@>5=3;+*-?&A?@;>@5CD17%33@0B6/#,.@C3,H5&12*,>8<;(2H%"1#;B7(3)",B/B%'3?*?)$$&';>G*$#<41@6?-C%A25A1!D?6))$/"*6'5<F/,+$#8$0@0B+;73.<>&+60@G(>C&!>4!;<84!0738;(*=?H$
@r2067
GTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCNGGCGGAACGGTCAGNGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTAT
+
#3B30D3-A*:A5</-E64<91HB-+F2<D7+@74F:=#/B<%5.,=G%-$8C=F"(;FE*>96=CG26'F!C%"6&3=.A5!4$CG<+"13%A*B+-;9-GA%#2)77%?:AFE<5E$:.-G/CCD4B7B":2&%%<201E?+@95G/4,EEH9-)<48924G4:,D)*80;)%*2;#**CBH<=>"C?#*43.7-9*
@r2068
CCNAAGTGGCATACTCCANTNNCGTGGNGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTG
+
!&%$"&!&&&&&))$%)*"&$#%))###+*$)$&#%&+*%()%!&'%&!*"$*!!+#%**!*'*+$(+*++(*&++
@r2069
CATAACCAANTGTATTTATTGAAAAATAANTAGATNCAACTCACTANACATAGCAATTC
+
6=H550G4HAB??D-D/*A(..1>3*3'E(*4:.',41G4,B,3B9A1:@#@&E.'>0!
@r2070
GATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGNGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTG
+
F">+#&"5=D0@A%#.&1%7@?/#:F1&.=3GBHG,@<-4='G-9F'4A0<D+%G:'%0A?+,G7':'.+28::09*?>;6.$,%G.::<3H
@r2071
CAACCGGGGACGCTGNATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCG
+
*G?)?;@?28,?.(C2"6#.!B?%3,/B8:-1"%2'#&/";?#:A%$<3?<?B
@r2072
GACGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCA
+
'&A#8A&'C7+E(@-4@<;B/94;C=-42!%1D5$%F://!E(!722>D%9?85E
@r2073
GTACTGNCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACNGGTTACAACGGCATTATCGCCCGTCTGCAACAGACTGCCAGCGATCCGATGGTGGACGGCATTCTGCNCGATATGGACACGCCCGGCGGGATGGTNGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCCGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGT
+
%'%#!'"!+)'(#+$%#)+)$$+($"'$#)("'+)%$$+*##+&#"#($'&(")(&#+($%("&#%)$+&+!'($+%**&&&++)(!)"%&+&%$)&'&#''#%!+*))#'**#"(++*%'"+""%(!+#%&%(*%*+'+"*")%#%%&+#!!((!&'+")+*&+)!#'))+!!!+!#'$#&'$)%'"#$#')**$$(!&)$"'*&#+)"+'""(*"!')')(+*!"$%)"&+&#)$!'##&(#&'#&$("**##+&##'(&##*&*)"(%+#"")&#%("%$+%
@r2074
TAATCAATACAACATTTGAAGATCAAGNAGATAAATATATTTTTTGGCGTTATGCAGGTGACAGAGCCAAAATAACAAA
+
6/06?&"8D4.8-9F58=82.4ECD.H>CF@1:*!8*8+:&>C6$,/'B:-(*#<%;@:B%8,*E6*/72B9;!B<97@
@r2075
GTACTGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACAC
+
>A%"EA#0;:(D,7#?(:4!3-G*A;H./')(*6-+:87H3(3C'*7/(+C;>)<3C
@r2076
GGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGNAGCNGTCGAGTGCCTCATTGCGTCGCTTTTTCCTGTCCCACAGTATTTTTTTCCTGC
+
59804*G&#F(:2&9F*+/-08*3/#)8#7.<5)G;+!<$:6E(-A%:00-5/(7H%>DB:.<D%4/95-;-6.@!%7B#3%--H=+!.?DGC=H9F/!"<E/6120&573-5H<8#8+1?(%:*%5?-9#.
@r2077
CGCGCTGGTTTAGCCATCATCTTCTTCCTCGNGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCGCATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTACCTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGC
+
+*+0::+HC*.<C"H$"*>-3."31<8"-G,!G(7678>.#.2<)H<%D76",;82BD+685,E9-4.#H:AD<-.41!,B4(F-#6><-5'6+57H0)<>8#FA$DE+$6<868<1A7D=7D/G6G'FA/+1<)8,$?';)8>:!);H$67(<#30A&1-.;%.1=</3/G"G(4!3C-/18;#@?'3,'B0>@'5010%"4/0@0-2%(3"!D34B)#::A2FG=+/D
@r2078
ACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTC
+
2F?--&/-8D"1D!=<1=(9?4+'(92,.C(H="76759)"F.
@r2079
NGCGCGACGANGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACG
+
"6599-*CG:'2'$=:"H6*F?/C$,B"847-9)'C3H0<->+AF8)<=$G,-+C5G=E*4%D,?-5E>AG:>
@r2080
AATTAAGGCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTG
+
@199#4#!GD5H;5>H1#?00D,4;16G6D.A31B035*!G10;@C6HG*;&-G.E58*=#1@%$@D?FB<
@r2081
TGGCCATCAGATATCGTTCCGTCTTGCTACGTCCTGATGC
+
/<>-,%B:8E?'@-BCD#;<'&CA(5(HB8"#?90CC,5'
@r2082
NNTNTNNTGCCACGTCGGTGAACTGTGCAGNCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAANCCCCGCTTTNTNTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTGTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCANCGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATC
+
!'(!!!&%+%#!''%%((!%'(($*&+!(!#%#)*+&++&(&))"(!)!)"&)#*(%"'(&()+#&'"$)*$$+&#*)*!!*)$#+!*+%!*"$%"%(&'(%$#!"+&(%)!))"#&&#"%"*'+!(""$(+$+%$&(*%'()!)"'#!'"*'*))(&+!(*+%#("""&'$%!'*!"%%#('%&"+'&&+++%!!#*"+"+(((++!$$#"+'&!&'!"'$$$!#$&'(%*$+)"')%"&''+)%$$#)"*'+"%('%"('%!)*+#!##&('%)*!(!")&*!)")$+%%#%'!#"'
@r2083
ATTGATACATATTTTGACCCTGAATTATTTCGCTGGAATTTGAATCAATTCCTCCAAAACGCAAGANCAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTAT
+
:3!;%<H)!%1:4&1=6+$1#&C?F#@<DDD.53AC%G2+)(;/!/+5E#!H#$C*"C*C,";1DC/$:.?<2H%8#/9:A6?/8!3D@94;+F#A.$?,C=G%)HE
@r2084
TTAACCGCCTTTGGCGTTGCAGCAAGCGTTNCAGACGTGCTGTTGGTTGCACTGCNGAGCTGCAATATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTNAAGCTATNTCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCCGCACTTNTGCTCTG
+
+=(#.7-7-6.<,8$.77#)-#';G>=BFA'7@.AA,=+H1F$-'B&?%2H6+E='..F<*;,F:-9,-?/%.".'F$+8G#)(#H)CD9%77'(*9C40(?FD?;<('H')=F:(9@.&,68&*F@3A/D&4:,;;45#:;5*/!#AE$/0=C-478,+21;;3;'D*H:+8811D&1-3)
@r2085
GATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAG
+
@'6!?*,1&F)@H8!D;"7E7,3075D3H/+'CDB81+@)#E6@ED4=3$$=.E8CAH2-&?;+D?DG;A-3<8+C?!4G0:"?%@;>-5%3G&G.12'%""4;',?&6G+HH:.@A3D">#17?8+320("H+$++/,*">DDG'A'3;84=)::70)7B*%*#F,@G-!'),H
@r2086
TCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGT
+
4H"<4!8$H+$E8/@;38<-60@9G"*(=A9$+-128284<1A:('+4#9<")-<H8D?9!4!4?/>"G5<?8,A.5)H75?71=;+A!;ADA&D=8815.+>+
@r2087
NGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCCTAAA
+
$E=('/,"/209BE1<#EC;21%%;>D+-E0;$*(GA0'.4CG0B/G)**@F-*%"D*-/+D;HF!:5)7G,D,00F+$FD*/>$>#/.F&0@@'!+-,B,>?/;596)9=/
@r2088
TTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGG
+
A<7<&+,)5G,0=A50:8G4A*+%H,.369E?!><%0>.E:-:&!<D83*$/%:
@r2089
GTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGANTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTTTACAAAACCGATC
+
@B:F1"(9@F.0=F-"';+65F8G,4EA6<E4/$$4'#5D"GH(#F!'18="%&F)E02-/*A03;1&A#*4+9&02(<'(HC@2B.2CH43-$6)D.4A&()H<7',!%+?E2/8B2AF@0?9"3,/40.*,&>0=9*,*
@r2090
NAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTA
+
!*"D03'E!.(#05-*04-5.&CCH.3),?,@(.F6'7*!@+(F"!/C,B)C'.12-G(+//@(C!>2-:E($4H;
@r2091
TTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACC
+
F'+;=&8%45#E=C+)&+E807?:EC2#8*)E8=45#HE=C2&3<$F<-@(:-+-:9D>"3>H,
@r2092
AGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTNCAANGAGATGCCACGATGCCTCATCACTGTTGAAAACAG
+
#?B7.:!2B81>(A9;,/=DFDD3-5F,,'!"C2;+F569G&062-#/D;+,0614*?-"@11=ED>,&',D24FC@C&'7,#7AC<F>@C?G'7*;=
@r2093
AGCCTTCATAAGCAATATCAANAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCANC
+
'*GA1==&$A'0D&A01'!+4<;D8)%9BC1B>:?95;3!."E+1B9=(H?4@,88>*@"G)G$%:4.H=D8&;:)855B$C&-/'"7E16&:F?%CE8">;!?/<&#A.#5=4<E;$=B&/(:G035>">F$:4GC5!#@A2E.0>$<))5#-H952@E@B@#C.@B=-!)EG
@r2094
GCGGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACNCCAGTGTAAGGGATGTNTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGNAACC
+
5F*<49,&%/A;D,'0>;:D/+)?"5,@&CG@,16"*C2G?GA5%5>H>E-%:*0+2>6G7/<D?5A%:8.%9%@=%D%)?)!F0F@)/!>)C+77EG#8F>7!BB#12+1:+A0)B'%&;8<?5)+B&%@F
@r2095
CAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGC
+
8FE5A4.$4=>9GC=+.+0!(+"-%F*DDA?#=E"'(513F636;0($+5754+)>D(
@r2096
ACAATTGGTCATGCGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTNATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAG
+
@5!5C#B4<B>,@718=3-61=HGHD#(G6'H)4A&F&+23)<7*GC2:-H7;+B2$>/+A6=4"0<@G(6*(*7>*B(E&GB."0-2%3(#@8*%FH5"1,:>
@r2097
GTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTNTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTNTATTCCTGCAGTAGAAAAAAATAAGGCAT
+
@,4!;>:A51E"2GFEC=#FC7,)>0;%B.CC.*E()'37@1;7?6D#C=8,-2$'+8>)1B/<2*:HD,<3DE23>#3G4D$;:B!333G4'%1#-(31=2?/2*!0/D=(1/98,3D*4.$(,!#E5,#83F<@"@-E$$0B@<#+;8@
@r2098
TGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCNCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTT
+
8986@E7<ED0<.*=+$,C(EC;"6DH?A&)B"F"!2)#2&9E!30+<7,/HH+$25425,0F>?FE*=1F/=FF<B';+:B"%14;2*H!.3&&D91G4!FC=;C?*;:76'B.+-0*0*4<>F.C<,H=$(<3;.+"/2',3"A*C'*2EG8EB0:6($2A*".-H80B9F+&@&$96>D.'/073D=HEB86=4@)8$7A;>D$E0'6D*5282A'*<ED>;9%(&F%"AH/=:#&3&/G;E:?<3H1B2:02><=,:;3,:/@);?-5D./5<G,2).D(G,*4(&D)0CE)GA9%=1*
@r2099
TACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCANTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGA
+
G<A(5<$9?@H<%/B,6(%A$(E/'*9E34(H3>)%@0968/2(/6,20<&.!H/*5H1%<%D-1%EE.$<FE?8,G>A8FC$"7-F0G?2/B:
@r2100
GGGTGACGGAAAAAGACATCACCTTTAAGGGCAAGACCACCTCGNAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCAGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTG
+
%+%#"!)%*$'!+"($#+'+'#($"!*!+"$$!#!'!#%#%(&$($!#*+(%*"*'+#(%(+%*&(#)")(!"!%("!%*+'!*)$)(*$%"*'%)((!%+%&()%**%%+$%'!%($)))*&(#*#&#*&"*%%+"!*""'%)!#")'!(%'(%()"!##%$+*)+#*&&"&!'"+!*!$*"#)#(!)(&%$+$!"$$)#'%)!'*"&#%*(*')%+$!"
@r2101
GTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCANCCCCTACAGCCATCTTCCGGATGACGTCCGGGAGA
+
+'$)&#%!*%!"*$(&$+'*!++&!++*%+$(+*!++!!$!+$""!&#&')&*(&&*(#*'($&'$&")'*#)$)&$(%"""((!'&)&+#"%$!'%*#%'!+*&
@r2102
NCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAANAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAAT
+
%41;$"+46$>+B.G+=$+E)19?4%+%>%"C72..>&985>;71"<)A%.*!;'!5@:6/)-B<%.5*>2B'+,5)+BC8**5AF$0G$.&6&7G%&@9G8=*A/D2<?H4.GD#:?B.).90&<7<?*=5$8B&D3<""6*222"#/@863-FD8E7>5/,"8%"D.A4CD(9!E-2;'
@r2103
CNGGCTNTNCNTTTCCACTTCTGATATTCCCCTCNCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAA
+
*#')%)#($!!$+""%+&"$)+!%$(%(%!&'"%*&&'+("'*$+!%#)$)+(&'+)("&&%"%'$$'#*)&#')("*")$+(!)!
@r2104
NNNGGNTCAANAAACNCCNNNNATAAANNGNTGNNNNNACTGNAANTCNNCNCCNAGTCNGANTNNGANGTGNGGCATCAGNNNCNNNCGNGNTAGCNCNNNNTNCGNNTCNTAACNNACCNAGNACNCN
+
!$##""$!!!#!"#""#!!##!"$!$"##"#!"#$"!!!!#!!###$$$$!"!$!#""$$#"##$"$$!!!"$"$"$$##"""!"""$$$!$#!$"$!$$#!#$"$$!###!"$"!$#$!#$!#""$!"#
@r2105
TGCACGNATGCAGACGGAACGATATTTGATGGCCACNGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATNTGCAACGCAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCCCAANATACGGTAATTTATTTTTCGCCGNGGAAAGCCCTGCCAGCGCCGTCAG
+
"$#(#'$*!!++$)$+((#!&&#**($&"&"!)+#%(("("!*"(!$$%+'$')"+!#'!%**#'!)*$"$#)$)&'&!$!%+#(%"&$"%(!('*%+$&+%$%*%'$!'$'+'$"*#&*#+*+(%*)$%*'!%*(%$$+#*$%)+$*$+*$'%(&(#('&')&+%!"*'"(*'"()*+$)#!&$"$$(&!$!%#$''%+*'*&))#!%"!*$!*"())&$&!$
@r2106
GCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACAC
+
G#&</>4455;=$*;.H."=)4'%7)B&A221:G(/5F2!3@;2B"+#%7F@>F+;%A
@r2107
TGTCNNCNGNGANNCNCGNANGCNNNANNNGNNNCNCNNNCNGCATNTNACCCTANNNNNNNCNAGNCATNGAGCAGTCCGNGTNNNNAGNNGTNNNCACNATGNCCTCTTNCTCCCNNNNANNNNCNANTCNGNNNNCGNNC
+
"$"#!!##$$"$""!!##"!"!$"!!!###$$"!""$!##"##!$#!"!$$$"$!#!"$$"""!"$##$#$"##"!$#$"$!#""!$""$#$""#!!"#$#$##$$$$$$$""#$$#!""!##"!$"#"!#$#"!$$##$"""
@r2108
GTCNTTNAACCACATCAGGCTCGGTGGNTNTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTT
+
("*)&%!)+&"%*)$+'*$*$)$&!&&'#&!##%+)$#%%&+*!#(("'(%!!*'%$"%$'**$$+"%#+%"$)'(')+&$($$
@r2109
NGTTNTTCNNANATCCACCCCGTAAATNCAGTCTGTGNTTGTCA
+
#)**#"&'("'((&'&''*#+$%)!(!&"+*'&)'&+&!&($)!
@r2110
TGGGTGCATATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGA
+
3<)((F4G>+0?.C6G-@$5BF)(.E"4H,1FA9#:>32;)D,#A&C"
@r2111
NCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTNTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAAC
+
*$&"*+!%(&'(%$"+#$)(!('!$*"+#"&')&)!&#*+&'%!)&%!##)(%$"'*$'$%"++"$($#"&")'###)'')*(&#')&*'*)%!%!)!(%$!'!&!$#+()!$'""
@r2112
ATCGTCTGCGCGGGCATTGCCNCGGGTAATCTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGANCGCAACTGNCCTCCAAATCCGCTGCCACCGCCGTGATAACCGG
+
D3/G,'=3)HB(,'CBF@D@'7/DC'/%E=0(((8-H0+-*.8C73(4+';983<5%F,E/35'A<,5958:0GC'11'GB'%D3*B'+,(D=3C5)?3=?B=<*,)>F316,&-C=:9A7B
@r2113
GGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAANCGGGCATTTCAGTTCAAGGCCG
+
47.7<!!=C65*'CF($E-F,%G>!$:2(G$!&CG<D,.5!:+A273F02D..!535.&.0H')))?-=G;7,A!(9;,3&%8+5:654.;H/B-!0F6.8<+1(C(F%F6?63F.!!",4)*CA-"&=<:0D/*1HG--/H8-4/8F/'F91
@r2114
NCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGNGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTC
+
&).9>@HGDE(:C28F,H5=>2:H>CC?E4@/E$69></(DFG2;):B24:0%A3?H5?$7""6F%-/8;C*+=C=?6/94+2'0FD/?<HF0F?$'$@=:G<2B
@r2115
TCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTG
+
$<'-&#A88-.6).&>:B+"9#;H0/00#72);@3.9;G&3DG.@!>-E+:E43$)6116*6
@r2116
NNATCATTCANTTGTNCNANCNATGGTTCACGTTCTCNGCTTCGATAACTCTGTTGAATGGCTCTCCNTTCCATTCTCATGTGACTCGGAAGTGCA
+
"%#$'$(')&#%(&&%%#&#$%%*#&$#(#!#%)')#'++*&"($$%+""!!')%$+%)&(&+#&**)(!"&"%!'!"$'"#$$#)&(("!()&&(
@r2117
GAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAGAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCGTTTATCCCTCGTGAT
+
28?#,G,1(,7'?.D,)<(2/+;2;@03'+&++.*=7?=E8C;#4&0=278BG*2";H7/!()<-1-=<<H?1#97'<!B"6-1@+$$+@;G%&A,-/9F,3B+@&$7.6;B9-D;".#>H7=//H'FE2&H
@r2118
CGGACCGGCACTGCGNCGTAATACGCGGCAATTTCACCGATCGAGNCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGNGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTC
+
+,+:>>!AD9HG5(3$54/;':7E,@!-194E"A9H,F*01"7!#1-7.G-6-033&%%.?(=9H,8=;(6&(&="(;(1A11%3>EG5=G4F@HE1(#%995@CF5<8=>F=:G3-5H($69
@r2119
ATTGCAAGGAGTTTATAAATGAGTANCAATGAGTTAGAGTC
+
@BD9#9$;$;)0&;%B9B633<26E$@&?7B,.671)0G$@
@r2120
GGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACNGGACAAAAATGCGCAGCAGCAGAGCGATACN
+
<*2=?4>A(E;;E=59A<2,/C2A<D*9$#@@/81@#!"3>G&=<B;5/A5EB.-65;$$;0*HFD,<G(-%<++<4(:@':>@D
@r2121
TCGGCGNAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGG
+
4&96BDC;+/G&#H)&G<%#=><<+1:=8))5$"0*0("/?,*C+6C?)*6?<@,6&61H=+;C04)**A9&5=+&6,?49"(*--&*-G.4E#03;A8)")54'?*:,#A"@G(?$@A9@%:$&F'!*"A;),G4+H9!>#,!?28"17@)B7=
@r2122
ATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGC
+
3:&.<C=7%(C!&'94&%:,<-:%(18<C<17-5H,9C5>/;,<G2HH:&'-?-.<<45H9*)B-D
@r2123
GAAGAGTTCGAAGAGCATCNTCAGGATGTNATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATAGATGCAAGCTGCAATCGGAATGCANGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGA
+
,F(E(8"F4C5@)CB1,9?E7+0/?7%>DD>EB#6G0G'!?C<$,3=E4&A'162A1:@/?&<06>9D1$/!4+EF7F36E28!D<?5B(/).C")B>!#H79.(5=8;B>E';4%G,1(925,/%,!<,04A)A$C2=(H;8;44B!39<A'3621$C#09>FC(#?"".*2+5A#/9#;:;-7>
@r2124
CGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCCTCCTGCTGATGTG
+
+,=!&@%A+A-57>C8669G&6&(&'=2+"6#A&9"2/#0,5,E);1/:,*--,:(4
@r2125
CNNNNTNTTNTAGANNACNTNNNTGCNANNATNNAACCGGGNACNTNNNNNNNTNATNAANNCNNGGC
+
!!$!!"!""!$###!!"$$!!"!$!"#$!#"$#$#$#$!$$!"$!#!$!"#$#"!""!$##"$!$$$"
@r2126
GTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGGCAGACAGTGGCTACGGCTCAGTTTGGNTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCA
+
<752"!.1#!)??2%!'$;B3FG%!(@?-C4H/EG,0A".5GH)'%205"0ACGF6"91:B1"078%51@'$*0%=#=D@>>:3&?!5-/7B+B@$&(36A,$6'(BA6#@
@r2127
GCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGAT
+
:D=&32-9=5@)H@ECF4%9C44*#.+7-)DCC!A6E-204:D7@0H6488(C4?B-'$&78#E
@r2128
NNNGGTNGACNNNCATNTNANANATTNCACNANAATNNNC
+
$$!#!"!##!#"!###!$"""$""!!$#"$"$"#$"#""$
@r2129
NGAAGCNTTTNAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATCACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGC
+
!%(%$+)()++%#%+$'(!)*!)&)&)$"%$%'$"'$$+#$"+%#$$(#&%&%+(+##(+'(*'''!(+!%'()"#*()*'$%%+$+!&**#&)*+$!#%)**$"!'&&)()&'(%#+#%"'%!%%%'+
@r2130
NTCCGTGTGGATGAGGCCATCAATAAAACNTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAANGGGGCATCCGTCTACGGNAAGCCGGTGGCCAGCATGCNACGTAAGC
+
!'&)*!+%'!%!'!!%$'$)+$)+)')!+%"!(%*#"&("&(%"#%$&&()&#%&"'#!+&$%'#$%#)!#"'!(#(+"+$#+)%$+*("'')$%)(&+*"*)#%(!#&*($*""!""#('!(!$()+$)"!)%&'!)!#)!"%+((**#($$+&(+#&!+&!+*!%&%%()%"%!%''$!*'))&&""#'&*$'(#))+'&
@r2131
CGGAACAATGTGTAACAGTCCGTCACANCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAA
+
CB@3H3152$/"&2?E9?++202CG94DG0(C=.$/!D.,;7>H')#C?'F+/9C1-D;)>-)2D+6;A%@F,/>*/D/H!=:0H2?'5>'CB>/+"70*E@HD>,.76'
@r2132
TGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCG
+
&A*4";7"<58C>%<"62A2""C&/?+&F#HA%B2G/+H6)
@r2133
GAATGAACTGGCCGCAGCGCTCGGGAATGNTCCAGATTTTGCTACCACCATGACTAACGCGC
+
AC"1C#BH1()33=/4E4)/2*/.8GCGAH:+EH=G*C.%(D9+$$87?(A*>:1#+82"B)
@r2134
GTNGAAAAACTGTTCCGGATCCGGGAGGCGGAANAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGANGCTGCAG
+
)&$H5D&A&7<+-&9!<3C<G,:H006E4-+;"3.2C/&!:DC>+D%*H:F2&#;<3%#,B*$-G%AH%14,@'!(D.,$$??92<<#7:1;F"EH&
@r2135
NGGACCATCACCGTGTATGAAGATTCACAACCGGGGGCGCTGAATGATTTTCTCTGTGCCATGACGGAGGATNACGCCCGGCN
+
$+72>%>&**9F*8<%3%E#,)E"=;H5+C,=-#9*,4!62*'%1B2ABCD<(6"*)2A0,&(@&8;%<2$#6B*6?C0'"8:
@r2136
NAGAACTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACNTATGGNTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTA
+
!(*'!+$!$$"(+'#"$"&#*'"')*#)$)')&("'%+''($)$*%$"+$"%*)'#*%$"())*!!%)()'!'$&)!)#$&('!&"''')&!('%$*(()'$'*++%(
@r2137
NANNTCNCNGTGCANACGANNGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAA
+
%%!'*"%%&)(&&*##*!(#'%)#*((+#$(('')#**'&"!%*+&($!+(%!$&#"(&!)'%"(!'#$*'("*$!
@r2138
GCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCNAGGTCACCAGTGCAGTGC
+
)4?D6'6%(,+.#09AFB%$H<1>00+"</0C3047."=G;*#)(F,261&F$4<.9'4(B96>G5)G3"B;$5.*.DEH=&5!*
@r2139
CATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCG
+
>@8/&G?@19'':D(##+"<=91DH:5(D%9:A8BC/6>F<)=9<.2%3";9:
@r2140
AAGATGCGTGTTTCTTGAGAATTTAACATTTACNACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAG
+
AB6545)>>EHA-B1B0;(B:0D%(9;B>0+2E2:#.D:*;<$-=..=81C>-B@%!0AE%<A9D2E#83:6>AA9?2=>##.(F*3/$G=AE7!H=BE;?=%HD1/'$
@r2141
ACTTNATCCGCACNATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCC
+
&')$!(#'**")"'++!(#&+*$$*&*)")("#%$)&!$%&!*)#$(#!$&&
@r2142
CGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCNCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGNACAACGGATGGGA
+
(36#@?;0BD?#),,&HC,*";;"'4C@*.%=3&+9@:#>3#39*)FHG2D9)<&/,#D(0!".H001('8>12-C93C)8/'5?G.03>"4$-4?:-+1">4
@r2143
CTNCGTCGTTAAGGNNAACANCNCACGNTGNACANTCNCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCGCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTG
+
"%%)"'&&$"(*&#)"&*&""'!)((#'((*)%'!')!+#&**+('$#!"!$)*)(+$&'%!&"$!'$"'+!')"))'(!*%$*%"*$'$*$)&'%*+!!%(+%"#!*#+(#')#)*"($&"+!'&#)+")%$""'$)*%(+"!#))$*)+)'$)%'*#"'&++&!$%)+)&!%"*&%')###"%"('*"(+!+$#'
@r2144
GCCCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAANAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACANACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGT
+
?F%:##A3)1260D)2$""*-C82D4$)),8;+7D&:A;E097=?5@/H.0&F%#">#?;H1+>".)!+B-:*B$'.(C8"002&%%;GE6+'.,$1("#-DG"E2H.FB?*F3,!'?FHB"F5!2%A/H>7D%F183$,B.!'0"A4=/;199-
@r2145
GNCCAGGCANNAGAAGCCACGCCCATTGGTGAAACGCTTCATGGTGAGCGTGTTACCCCGGTGCTNTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATANTCGGC
+
%"&#(($#))"*"#+#+&*$#(($*"'++&()#&+*"&*+)##*%#"*#("&'%''$%#((##*'$)'"($*()*%"''*&'%'$'$")!#')'&(&*(#%(&$&#'$!%&'&#*$'"+)'
@r2146
TTNAGCTCATTNCCTNCNCGGNTNNCANNGNNNANNTNCCCAANNTTNNNNGTNNCGNNNNNCCGAATNNCCACNNACNTGANGCGANGGNTNGCN
+
$#!!$"!!#!!"!!#"$"##$!""""#$$$!""#""""#!$!$!!"$"#""$"$$#$"$!#$$$#""$$!$##"$##!"$$"!"$$#"#"!#$$$"
@r2147
CAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTAT
+
+()'"$%(""("#&"*&!)$$!"(+(*)$'+(####$!#$(#)+
@r2148
GGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATC
+
@%<@6+,"":7#,"AH<+D69F"D'0)44C.CG%B(":===)&:,
@r2149
AACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCAC
+
"1,E+H"%+:5,G9F8@H'E(*!,8!,%4B.4E<B,H(;1.:=GB')DF2!#D/H69!02
@r2150
TGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAANATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGNTTGTCCGGACTGATGAGGTGCGGNAGCTGCGGCGT
+
;9"3=H)37@9D"E;$E<(/+++-9DEB986;@!BAD:((%-,197,H"E>G@B-->"2C&D%5&)5%0H'=>+/*48;BH2!5F-%H7>)8G."<>=DFA,?6,E9#A5@9A-$%$6,B&)2$@2A6<!'.HD9?7@*4&)581=@9?-262H,)2(<7$E('
@r2151
CCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATNTGTTGCCATCCGTGG
+
1;A;*:917B764=F24-FA!7()"&#9=<-0F4&:+E."BG81&80!A4E1718DB4-5E19.B?=9C1<?&+
@r2152
GCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAA
+
3<8C'%?*!-6(';+)H#/H@F>2(?)0&%;,*$8=A!#:8F?7/ED3C6G"!%1H$#
@r2153
CTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATG
+
?9%E+F9#2F*A79?11>2&A'8EB4()%+=;C%<:4";AD7C48#'/=D.<C&F:@E*A/A6=5E@<!<;C;A)-H*@/2&?"/%!<*F067,$!H"%82!!!0!DB95G(
@r2154
TCGGTGACGGACTGAACNTCCACGCTGACCGGATTGCCACTTNCGTCAACCAG
+
;F9@!+F%.0)%8??.@'F=F(9;&,,82$3&!?!&,4=3:.#%,/D-G,';%
@r2155
TGTGGCGATCCGATNGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGA
+
BCF,G<$6>#1/+1!2%D(#+)HB+@5"0*6B$6$/;/(2!)6*#;7C5"*E+7:9?:>%#,@8'5,,5C8>(<H"(/H1=$!?#@(0,*$:.51.3!0
@r2156
ATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTTCAAAAAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACANTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGAC
+
,&$%5C%72)/3-AD8/B>A.1+3H@350>4&'=G#2AHF?8::@A<+)C&42,FB6"7.;'!8+&>?'+8G0(G0#98A39:C&++8%"H7;?B"?*)>/-:(?"@=--.E-B9-9%;+#.F(--6A%8>A8"C+*.3?=75C5:(#B?G08$<E>#'*=4C*%)EG;4CAG"/?=(+%9F-B%565'.$8373>1'G!)
@r2157
ATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAG
+
.)B>9%36!,A5@6#?!;4.$8#'%#9,68F9:9$/1C()6%:DG?
@r2158
AACCATAATTGCATCTACTCGTCGCGAACCGATTTCATNCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCAC
+
1@76(B3!<:.#!AD*$C3D904=:(C0!+,1!'"(F"94),7'D+>E;%H=A?#H!<,.;3(+-!).$,/.B6?4&;1G8C!@5;7)'-<06BG($)=!12+.EB:B'-(5@8(%.1
@r2159
TTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATC
+
FA13"&):?/6%C!$;$H>68GGF2<<8C,,0F2F!/D0.4G"H()F:8.902>5!6%#*@E141';*E@'C/E!:
@r2160
AGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGC
+
?A="'0%>@<0A1*47=>,>#BEE):4)*5(?((>BA!4(+5?1FHC($?:5G)D2>C)F6)@8HC7E!C(&@,6!
@r2161
TCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCT
+
G"A(E$"-'C<:7!%(!5>G72#+?03<C.8(3/!:F<C,
@r2162
CTGANGCCAATCNACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGA
+
0(G?+38&=E=6B91%C.+"'#,>+/"C!#*H/4'5:=/&#.80#E,H<3FF-20A!;@D<,H9.,E:<(EG0B>+G+,H,@785A2A"/;
@r2163
GTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGAC
+
@63#$6)(/=)821+DGC1)0E)=)4A"285!=6H6E1!;!0C"*D,A*?;@),:
@r2164
NNGATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACNAGGTCACCAATGCTGAGATAGCTGAAGAGATGGC
+
').1>+4#32),A-00-E()B=%),!6DG3*(#&,E%$=;'A?B&G*4E:76#1E'E@)2BB&B29;8)"D4;016+,&
@r2165
CCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACT
+
&F"#,8"H;C*2A$:8,4+(;=&"*F1D&$B2B&<.'$+.>;5;$+F"B:DHE>9>,AAF<1/'-/:.'@C#?E=!)#<G7$65D'E0:&#&&E4("*-%+-H;6=,097(23%(@*0.,/:G*+)?%DG6<,:E03@"-4FGG*1+9(A6C
@r2166
NGAATACGACGGTTACNCACCATAAGCACGCTGGCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCA
+
#+'!!')!&(#+%$(&%&%%$#%+(!$)(*&)&$$#"%#"&%*")%)$&#%(#&$)'$(&"(*%&)&(((")))#*&!$&&*%#+%+#%*'$*&)'!'(***')"('(+!!&)!'+'%*$*)+&
@r2167
GGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATTCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCA
+
0:@06CG+6AG9-?A8FG4%?6#)%<C)'<346>C9%+:6"#0+@3AA9=C"G=#+-5$-=C4G>;7C44$"G-<!(B,59=99F#CA,+<86@F;:,@27,C>H#"+4=@,-+8$A)-<"#B3:+#E)11D>,<31HB=,B4>(6<DA>)%2/!<C438E9#")C//HF>62D<1"F1%4'!GC@#4G?$B4',A-+=+'H2?->5<B;)07(F5/<7<./B484=5A)7;:&.B749
@r2168
CTTNGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAANGGGCGTGGCTTNTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTNGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGT
+
#'((+!!'%''(%"%)&%+")!!$''$+'$+!%")*&(#(&!)"*+'(!&$'!+)&%$&+$&*&&$)&!!"#+%)#+""'&$*"*"%#)&*))%%)!%$#"&&#*!"#&%($)+&!%((!+'+!##&'(&+(+)(&+&!($&"&$$')$()#(**+"!'"*((%&+&*&''!"&$)$&#"(!)#"#"+')&()('&!'%*)&'"#+""'!*("*""!&+))!+"$
@r2169
GAGTGCCTCCAGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGANAACCCGCGCGTAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGATGGCAATATGCGGGAGANTACGCAGCTCTGCTGTCAC
+
(,8<:.,14C0&3D**C;-,)42"=:6+6<+*C"G9*+F6>'@+/B#H=A-,8A9-C78"#/11'A>;H6!CF$F'<E1/14%)@!;?B33"6GD$81/)""2,73""$%GH:;.D/=E%.?;CD=2,@H3@&=84E8#4031A1>$/F5DBC4F!>1H.E=.8"8C3C?0B1>
@r2170
GAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAAT
+
913295>8(%$8'*04>AF?':GF&#/E9(,9A/)5;)G+2+9
@r2171
GCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAG
+
?D/43D#2);*&C/0<14/*1D$&&//61*)(C,B,GC8A>5*3=HG.(2?0$/$#E.*38+7@>"9;/&3H6H!055-6)7%,4='!'
@r2172
ATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTNCGCATCGCTGGCA
+
%-#$D*2G+('$?##4ABB9&BA47*"BA;8$(B29@63-@,D(@>.B#+="EB.2.2@.F'CC5;(%@H"&7BB!%?&5AC*+%B=&%8.-5:40+EC?-.9<E4=+AE/ED6B@3%C-%2G<33(F%(59E)C?F*3G<%=;%:%,%F7B=,'95BAH6CD*)=*:,<C%*3&::(:@#'4?:*&2!GC$H506A7B02<>DCB<=39
@r2173
GAAGACGTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTAT
+
.!-<7E-,E2)..C::?:1<0&5=<886F>E/-;3A"'17%".F9=?
@r2174
GAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTA
+
'5G9A20B'AB5&=6;"5F:.?"3<35/:0'?-8G2+?-46>;E%"EH6,7&+=EF:C
@r2175
AACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACCTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGC
+
2?.%5B,$G;05C'4(C")H"1;G''!>FB35E<9@C='?)=&68>9:,8%/24BF=C=1*4+;E0+:*='B/72?/<C8/3373&69$3<%HG3(?9
@r2176
GAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCNTGAGCCGTCTGCAGGT
+
3!;88&6?/.5/0".AE.%&D&!"10=6&%6?%(D9;6*0@+6;C&/';,*3!ED@#>HB*-,60*2AHC@B-$++/)'>*#F3A:379<AE08263!B6#/&
@r2177
CACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAA
+
11>B;&"<;/7-"*A9!%!E@?*9FG;&$4*,@;0.+E;F"!)!08"F./>"/'F.D)2(:&AC7'E,-@$1%>?3)=)!>*,913*9=':FE-.,<&3*/E(<.<A>@:<H8%>4,7-D9A;):"@080
@r2178
CCCGGAGGCCTTCNCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTG
+
&*(*)%(*#%)&''*("+!#!$+)"(&"(++#*+$!!$$$+'')'%&*('%)*#!&*)"*'*('%&'$*)&+()(&)"(((!!%!+&)'')%**'&$)*""!'+%("*&''$%%&(%$#"+)'&*%%'$#))%$+)%+'))'
@r2179
GNGATTCCAGATGTCGTCTGCTTTCTTATACGCANCNTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCAGATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCT
+
#':D2/8<3G?')*/?9#<?:4">.9.-EC-#D$80!8#757!#%,$'F&7$6.C'12!;>8%48@0."<%A5&:CA??H((<<>H45")84"A3@3AF0*@A65"H'=-//=H889?132!6!#C@B+-);+.D0&)./
@r2180
GTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCC
+
>962%"=0H#7><7.<#=))<920H'#4@28-9@+5H674;$8&
@r2181
TCGCTACGAAAAAATCCTGGCCGGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCNCTTGAAGACATCACCACA
+
HF6#8B?7G#=@;(6.B.=A7G!70"=G27DC?,5'H03)3,C=F,GB*'6%?:!BD4/@=*C"*=G)AC:/!H/+G+"6A,.(.)8*;7;;/GHBAEC'F(90@?)3?7=:!%6*?82@
@r2182
ANCTCTNNCCANTTNCCANNNNGGNCTNNACNTGCTAGTNNATANNNTACCANNAAATGGANAGNCTG
+
!!!##$#"!$$#$"$$#$#"#"$!!!#!!###!$""#!$#"!#$!$!"$##""!!$!$!#!"!####"
@r2183
TCTCCNGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGNAGTTCCAGCACAATCGATGG
+
64)4'<-1459/&'25)93%.596>=)&;$7@.AG'>07%9B(+=8(>D',7&#'/"84'/8&*6,>*"*G1D
@r2184
TAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGA
+
>"74?0::7;A7=H(D1!1GE4!B</)@./G)17.A.$*5+;3G83E2<!'/6G&"986B)+18$?AA%GE6:4!F'216(E9=2?.A8
@r2185
CAGTAATCATGGTTACGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCCAACTT
+
B.7@E=)""E%%;605)EE'AG<>E4C<60@:.#=947(#344,3G'85(00H!8">&15E,H#5->$=91;/
@r2186
ACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAATGGCAAATACACCAT
+
+"@7GD--.3C>%B5"982->;+3>1>D-4A!(;-D0CF#166%2$#,/8*B<C8F45GED*%&29#@F&0@D
@r2187
CAATTTTTACGCCNGTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTC
+
>36#$G&21:7H$?15",.?,6//"%4:(85D6$H<7<D!"(2;F>(#@&F;%'F=9656%2
@r2188
TTATCGTTTCAATCTGGTCTGCCCTCCTTGTGTTTTGTTGATGATTTATGTNAAATATTAGGAATGTTTTCACCTAATAGTATTGNTTGGGTAACAAAGTGCGGTCCTGCTGNCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCT
+
@85=5A"AFFE''14<F8?&*?C)-BD287:>7A$+@@,:0)9'=A04.@580'%;9H*=D:1B-@:.(E"44H,%<;C/-5B>'3=D$&2ED-FB$-/$HBA20);C3?/3'<1D<83'8>G(:6$'#C13%H$*B$"EA648++A,CF5+0$2+C7A(G:=="?GCA
@r2189
CCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCC
+
=5+%+:<FFEE?=82-/2D03)G@/5$B6.6#-&4/6C;4H%"-;%2%>"D7AC*)!:0D8+,B5+"@<&A7H
@r2190
NCCGCCAGCAGTTGGGCGGNTGTGTACATCACATAAAAAAATCCCG
+
#&G0.6=%;)7404#%/*/85&4,2?)D!'$&!<<'1,F*32<%+1
@r2191
CNCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACG
+
'*/7<=;/$..%&8"7(B<4G!>9>E#=:6=2G)++0C2BB>49)F.%+-/$BE+E0+=7@=95,27#:B"(1&D>+:<>0&2!*CH14&:>=G-@
@r2192
TTAAGTTTGATCCGCTGTTTCTGCGTCTNTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCG
+
:=.:17FA72,,55/??A6D*,&H@FD@G)G76CG01-#29E?<CD"7:>CB"?0!E&CB9E1G;C7"!45A@8;B4A3*98BD%7<,<6D/0)8F<(F3,F#D
@r2193
CNCCGTGTCAGTCAGAGGTATGACCATCACCGTGAACGGCGTTGCTGCAG
+
($)(')+(!'%*&+"%!%$"("#+#*))#(%)"%&!'%&$(%('*''$'%
@r2194
ACCGGTATGNGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCG
+
8))>=@(%!@/,69<-#$*1?2$*#"9G46B-E%*(3032(<=4/.9+7H<2<E/@262#09+&AE&B6C*57$>A):$4,61.8A0)A);4+)9)$;DBA8"77(!=5'G4+5?%(>0-H/B9/1#),D?&@A,-5.$'"*325HF%807F?,A6A6B@/@(>>9'?-;6,
@r2195
GCATCGTCAGAACTNACACAGGCCGAAGCAGTAAAAGNTCTTGGATTCCTGANACAGAAAGCCGCAGAGC
+
00/<")79/4<3<8!;'*<H$5D<:@&3;/)"/@D508!7;4!B+,;!=6/630431)/-7;/+/*>A&%
@r2196
GCGAGGAAAAGNTNCNCANTGGCTGCTTAATGGCGGTGGCTGGTNCTTTAATCTCGAT
+
(#'#%$)!&"##%""!)+*(#%"))(*"%*"+*%!)#%+))')*+'"*+"(#('&)"#
@r2197
ACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCNGATGCGTCGGATCGCCAA
+
8"&4).3$+4(<"*>/9+!A?"=;+D1?4'.>#@:8#>4*13,-F!"#&:/$A86*5:.$-D71*B4CDG<H7(5C$GD@4D>#&<C"582#8/
@r2198
GTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGNCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGC
+
A%1A3?H3*>>/@/A"9/24,G9037>5?(G!8,,8@#:G>B'5<)$0>349:2%#C<*4D<801",:"89.?%H0'-*B)9+2'@A54E+G/
@r2199
AAACCTGACGAGAGAAGNCACCTNAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTNTGGAAGGANTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATNGAATTTCAAAGGTT
+
"'%)'&+#*#$'"*%')'!+&+")&#*!!"%%#!*)$&"!)%*"&%(&)*")))*%!$()!'&)$&*'*))(+*'#!*%+#'*%"#*('(((*%#(%(*(#%''("!("!!(#'&(&""$*"*$+("()!!)$!*%&((#''!%)#&$)(!+&+'!%("+!!%#&($"$#
@r2200
CGCATCTCTTNCACTCCATCCGCGATGAACCATGAGAACGTCGTTGAC
+
5A:))5309-#4A$BCDD8,@42">A-FF;F:7&8&%1H7/<6$B<)6
@r2201
CCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAG
+
5*15G0=-D!43(78H-150B?+/7)6:*.7=7/*5F"?E4=*#;1.=F8+/>#9@
@r2202
AATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTG
+
2,9G88D,4H.BC0*E<><60!9:A(:H:/>!."@B<70=5-F
@r2203
GTTTCCGCAGCNCGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCG
+
C.$'A?"-:222!14!4F02F:#&949H8/0D!>DC,F.GD4.&B+!,,'6'B(1B5#:;#+?78
@r2204
AGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTACCGTCGGCGTG
+
*7;9G.<>9(G"=72'8340)>,7@CF:H,@+<42@+9="5:?@/()G)468<*<!5/)D2"4;14%5&>-H190<$-H'(/$-H;7H=??8=":$9>2G"E5E,8
@r2205
ACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGNTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTCGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTT
+
A<=31<CB&?-'4+;')*3#=')AE:?8C+8%17&)"/05A78.?D2"@*+8(+);!*E%&;A)-C&<D)D24.8C1-B@)-:(;B&:57E=*AE&6H+%G&<+4;8"A3C23:>@F"G6."+22H.%-B(,82!<*(:%C+B043E$;>;#3:E?1'=F92$+A&;?.8B@DC2&FE6FD0A0D3'=E*7BC8+**D3;15?%"1172-="2E)3-5"-#@/'!(<<E:.E@@%8E:"B#!=)10
@r2206
NGTGAGAGGTGAACGATGCGTAATGTGTGTATTNCCGTTGCTGTCTTTGCCGCACTTGCGGTGAC
+
&<$G7=>?0CG&?!/B9.CC-21+D407>57!&6C=!D##E6D'>/&2?7#)0?>F+?7>.F'!G
@r2207
TCTNGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGNTCGTGATTTCGGTTTGCGAT
+
5A"-(GD"BH.=B#G=;.%E9)%/EG2:?9'=4>6-*:BGD-+D30?HFG:=2(AC+00C983>.#%FF;H0#;>&G@D4.@(4A-A&44/14G@B6!&GG(+279D:!"-6%
@r2208
GAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTNTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTGACTATG
+
#?<2AC*7<1=/4#1<B#.>4#$:,0EH6095?.71-A=1/G'F.C)4B;/.49A=1(-?HF.?1%C$//8A-+'C1D*46-3=GBA74=!A762H%F
@r2209
CGACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTNNCTAAGG
+
24>9?A"?;1E'4;2+?>C?$C'@GH#1!-4B8<8C';=F@!6'A<;$A")C6(>F
@r2210
CATCAGCGACCAATCACCACAACCTGACCACCNTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGC
+
0'G-),A9:6:?>"+5,H#:?7>G%+)<C;B+##B6B,2=)3,:H>E15&B#:E8-'</%"&11!/-=9C:5()&E!(91H/=<&D2
@r2211
TNNCGNCCANGCCGNNTCTTNCCNTTTATGACCCGACGGTANAGTTTGAGTTCTGGTTCTCGGA
+
)%'%"('(($#$&)"!)&*)$#'!#''+"$(&%&$*"*#)!##%''($%()+)$'#"#"#'(&%
@r2212
GTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTT
+
'-A88:6:G9':!27D$7F;4!0B=;+BH3C,).<*-)9G744,;,)C)*:92EE5*1!C%>-&#?%"%;C&'18#F<;,G5#C,+@4:
@r2213
GCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATANAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGNATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACNGGCTGAACACACCGTTGATGATCTGCGCTACGTGCTGTACCTGCGGCTTTTCGTCGTACTGT
+
-@1(A2?8-E-D?B*%8E5'9(:2!7);?'..D(.*32/CG!HH852;(-!CF4&,B,(!1:(@)9,<87',&HH)1,(3<;872908/!C/F)CB38/;0D.#-/.F3*@5>?44?@2"B<1G+>8(A#4+/3&G;0EH<(8;-@7=1G)+%8/&%%H:D%$-8)E93F>D7*!%;+;@"$B%0B?9G3(9F+FFA%=/';=-B4'>*=(4.9-(C?&#"H/-,@!3=</'&94E03)69@1#!G/H;7F4C355"5<.H!#=./A-%6'6)A=C@'867%1BG5G@@5$30?,C;&G7!2/FEEC5G3>0@>*7&7;5254/@?4("BB;(2:<:<''@!0'A*5#;1251("?%>HB1E@8'>#0:(2;1=>4/'
@r2214
CANCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTC
+
1=/*89GF/F)@#=3<"!:-F%9B$3"15G(<'84!,C4$#%>(5?3G!<+,=A!A6AB$-%E0/6;A6
@r2215
AGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTA
+
;E+$91!E=C@?&87H3E><,<?B!@?1/:75H6&7%E*D
@r2216
NTGAGCAGAGTCACCGCGATTCTCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTNATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATG
+
9*!)B;&G0>.@5G.6C6;@A9=>,+/.,;1;3;45FF8AF@!B%!4-HE:,G3F:&.<@8*)F0%C7,5BF&,)$AHH82>F$;B.34%64#*F)&G(C<:#0$>B+3)C*C8H24#*)&
@r2217
TTATGCTCTATAAAGTAGGCATAAACACCCAGCATCATTTTGGAATAACTGACACNGGCAGACTTCACCACA
+
8;>66B%4A.5592+57#FG.B.""@58D'#:.20&9C5<$@0'%G;@CC*A>&$#D-F?.B"5#0B=GEB,
@r2218
AGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATA
+
&>"(BGF/F<!24D#E5#22CD;+<>DG8A3(B5<9#29"::=>7AA&H1=C@<12<8E!;+?*'@79;AA-
@r2219
CATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAGAGCGAGGCTNGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGG
+
1F#6H".1A*(E0++%';)GB$6-4HH.CD<=?%(3,?'EE<H=AC=882D?(G9'%##=*F<B)BG0/>9B9+G=/,=17-%1$?2,5*.?'.<=./E:;E"8::)85*6:'.B!<,'CH13<<'?2=2/*E=?:)A(A(D!
@r2220
AAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACNGAATCATCTATNATTAAATCNGAAAGACGATNGGTCGCGAATACGCTAAAAGATTACGAA
+
A6'E33,3A/<7"#!,*$74&A1)=*GF-@6.=0G'55H153=5(5B&9-,35G=!B#2)8&0@$>*.=54$-(E'D<5&**?2?)!G#C&)G9'!F03!2"/3!-''@=)0*>"(G&"%2=@8,;.@7)B)<9A7AD2&+!1=.7&95F:*<%'?6%
@r2221
AAGCCGGATTCGGTANGGCTGCATTCTGCGGTAAGCACGAACTCAGNCAGAACGACAAACAAAAGGCTATCAACTAT
+
@61*<39=:@.G%64+43FD-4%))#1@)>B(5:;0?8!-!GC3-G$5C".?@2'<4".)3:*)$=D,>:0(&18A3
@r2222
TTGTCGTTATGGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCTCATATTGCAGTCGCGGCACGATGG
+
(+"()&*#%)&!)$')+*+$)(&"&!#&**$$+%(+%)%&(+$!')(&(%"*&%++&'%&%%*#&"&"*(&+")"()$$&"*#+"+*%(
@r2223
AACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGA
+
8+6@>7'5B'"5?,69G#!!G<3=D+F5/B>-*58A!*-"4H95?H=##E#'+5ED3>;,:>1ED6BC*$"D+$;*#!@-H*'('DB6#CA=$=)-*'?$48$$2
@r2224
NGTAAGGCGNTGACGGCGAAGGAAGTGATCACCCGTACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACACCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCNCCACGCTGACCGTGGCCTTCCAGCCGGCGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAGCAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGNGTTTGCTGCG
+
,?+=8*9E++D##"0<%<7@5-3.&)5&B25"B+E6B>'DH@/=2<B&;C4):'@8,-A6H-8<,50H+%:9,;*94@:,BF>9?B%:";>15=D4D3E5F65B???2A&B@!D=,'B'$0,.+1$(,5@F3)C6F)$>D=D./="3AH(8>>@B"#<=5CB"'C%5<-B);(,881;)5?0.>)6D52:"@&>-?+?7B@<-'7B@(?<"@BD':8BA,2#%>?0.3+##:F%"E1?9D/%B1*7?F@#2#58?02<23D"E35(+?(2ED".-2*.;)$>E5+%01;E-=&9-G&0>?"D5=?,/,,F@*#8/>A@5).C2?(4->!<
@r2225
ATAGCTTGAAATGATGAAGANCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGCTAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACNCATTGCTCACGAAAAAAAAT
+
$+!*+(((+(#'!*!!''"++#')!!&#*$&+%"&"#'!)'('&!!&%#($'!"("$++!$'+'(($$"%()')+!#"&)!(*%"!#&"(&)*!%'#'%"#*(!*%##(%!*(&)(!&('+&+"""%*$*#!'
@r2226
TGCGCCGCGCTGGCGTTCNCGCCCTCCGTCGCTGGGCGGCTACCTCGCGGGTT
+
:E3"752<6!D4E?;-GE@+?&6A<F&*($?1D'<@2H;$(34<;HDB+*>*G
@r2227
ACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCNCGCCGCCTTTACAATGT
+
14H'<5D80:+=)&'DCF"HC.+B5>%AHB0H8)#;;$)-G3:49)%.;%
@r2228
TTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAANTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTG
+
&*+%*#'+$#*#&'*+&'(')$#$!)#%'&&("%*#'(%('$''!()%!!'#$*"")$$%#*)&'"!%$"!%)!(&%#(+++)$#+'+!)&(+++"+'%&!$+*(#*%"'&)!"'&$&!$'$!&*""!&'+&#*"'$$("&%&"&%#!)&#)+"($*%$#(%$(#"")$+!#
@r2229
CTCCTGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATAT
+
"*'+&##(!#%+$#)+#$$)&*(&(+&+&"&($*$#+'%*!!'(&!)#(+%!%#%*%!!%%$$'*"+*#$#()#!"$(**$#$#((+!#
@r2230
GTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGNTAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTTACGGACTTCGT
+
%)#3#8C0@=/D')757"H(>&1=5C437@#CA!7F"@&,GF82:81=A!.90C?54D375@5!6*=5>7?G(:B8&6,7AB9D.C<;$4+;H$"<EH)DG7<344&9B<#:57>%4=C7C>C!()9%+&,'8/=&8
@r2231
GGGAGCTTTTNGACTCATTGGATATAGTCATTAANCCAAAATTTAAAAGGGATANAAAA
+
;6H(<%H*!&).A$/99'E,7G"E<D9)-#$B-*(64311=5,,#F#D@@>F2(,=4'F
@r2232
GCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTNTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAG
+
<31@/4/(F0?3FC*D;7$+:C;)-4-$0HD:;1G45-@B2H4>H4>@E;E##".AEAA+4-;D/>%2!B1D1;;@#$1E-"=,"FF+E84G='7;A/#1;9#4CBF,F0:/H?##1G!#:E4(;EFE9)BF;F5E=(
@r2233
GAGCAGANAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGC
+
/<?"63=C!5.@4!F1B#++2A0"9EA:*$4G(G32G,,)$H0@89(,9)<!G&A62&6(*(/"')6F"E9)3/#,>%#%(@7E%%>"D8*'>7"6BFD/@A<):=?2#.2<6A!-2;&597.H"#<D8;/3!%E8=)!!D>G2(,/'+'A!%FH,"+7"=
@r2234
CCTNAATAAGNGNTNNCANNATNCNCNCGTNCGACATNGGCATTGCCTCTGAATCGTTCATTCATATATNCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAA
+
%%$%("'$$%!)"##!&&!&*$()"%"&(%!&+!&!*)#""*)'!(%%**&%+!(!&&)$%*'+&"!&)$!#'%!'$')!'"*#+)'%&'!"%('"*)!#++'!(&'+&()+)%)#("+#""$%)%"&+&&)!$'$$''*"))!(#!!(!%&(#$))&())#$$(*%##"
@r2235
TGTNCTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCNCCGG
+
??/7>!G.%6C4%HE>E+8+(,D,D25!99-7*!$*>"&1))?,()5B&3HF:5@C+C3-
@r2236
CAAGTGCCGGTCGTGCAGCTNNCTCGGCCACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCG
+
1F:)'&D$B--0>69%H#%38F2AB'?&--G8AA%*B'99+&6"!5&BGH?E4=>EAE+=6G)7<6&7$,@!-.%C2-B=@>?FH4E9EGHA8%$"?!$CD2+##,;DF+%2G')0B@8H
@r2237
ANCCNNNNNTCCNCGNNTCTNCNNNNCNNNTGCGACNCTGNNNTNNAANTNNNNGACCGNCNTCANTNAANNNAGNNTTANNCNAATTANNATANGNNCNACTANNNNNTCGTNTGNNNCNAGNCCNNN
+
#!##$!!!"#$"#""!!#$"$"#""##!!!!"!$"$$!""##$$!"""!$!#"$#"$"##$"$$"$!$#"!"""#!#"!!$!#!!!!#"!#!"!!$$#!""#$#!$"#"!$"#!""$$$""!"#!!#"!
@r2238
NNCNACNANNAGNNCNNNNNNTNNTGATTNNGACNNNTGCGNNTGANCCGNNTTGNNN
+
!$!##""#"!"!!!"!"!!$##"$!$""#!"""$$"!#"$#"!##$"$#""!#!"""$
@r2239
TCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCNGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACNACCACCGTGGTGCTGTTACGTCTGGCTTTCAGC
+
3E=#B).C;*B6;6C=F+%G#<(5#435,EDF0'56.-80+9&(-<E;.H*)>F371>2/,E'=?,D'(<'=9=E*F1)+2)#.(BF0%E!&>)G.#%88;@HD:B&9A6D@-#6A)6#3.,"#5+)%>*%&/':E56%H2)6B&GG(+:DA>;@H@=#H$'5$0+HB!#3.%%/55"7>E#:.7A3E@6"1=E$:D#F7G)H4$<35DA$$.=865B!A97ED0%?9H+-1C$>)&A8B-%5E%E(A59!(
@r2240
NTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCGGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACC
+
"9?+4DBC9A1E$<C>,(D9A8'F*->)D88623,7>+A*A!3)9.@,?B5.&9H1:<-:?#H3,>9/<8F9+,
@r2241
CACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACNCTCACATAACGTCCACGCAGGCTCTCATAGTGAA
+
/@03$(+-,=H&$D.3E@G6/F8!>BADG#4'G<3+.1(9*8>9&%8,A&GD><7$@6;C"/@6/=%,:C4,'#!4?&
@r2242
ATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAA
+
A"&-!%7$G,C+F"0BD#EA5#)3/<<A0:G,C+(%F%9.5&B;4?G?9A+$?!9>-($F+3>,$G18&%)"
@r2243
TTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGNTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCANCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCC
+
<,)?3C0(F8?C)"8$.:057A13G)@'?*"4"4(FF@$:#E21?4+%02%8(=100HH9;3%=@B)$2#12,A>=;)73,#:D5?A0!@);?AH(2-7AAGA,E:'56<#=.#8.$H$->=8D:$46+@1B;G"EH4B9!::(;<=>>,$B%E2H//')23!3%.)"5:'<0/37"/8D.B(<#>;>F&/G))'!FB'-$::*C.G'C@$F379&89/C4).90G8:8@C#<CAFA'*<$=>/%1/9@8$)B$&0H8<GE
@r2244
TAACGGGCAGNGGCGTTAATGCCTTCGCGCTGTGCGNCCGCATCCTGAATGCAGCCATAG
+
EAD35+4<(&!*@:H.BCB!&DB0@=3*?1*0+8;F<D+/>:EE6>9?=(D;(#:3A@"(
@r2245
CCCGTATCTGCTGGGATACTGGCGGGATTGACNCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTNGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAA
+
F?$C7G?5A!@-1$9;?$&2$C=(?()86D!/73HA:/*-A-%*F=C9476-!D+-:'0!(@E8:.<>G/&*D2<":/"@$D-":7.GC?C%/7FG7)+736(D60E*>GE@?<!641?'>&?/?%#B*8=A#F6"(++(H<5G+'*&7'6/$DBD.,@!&D0:1($D8?"E6C-?H$+">@17?-)#-20.:B2<,C9B/>
@r2246
CATTTNTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGNATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCG
+
?,<F08DGC$67(!+%:>9>4%7F?5#B9A8GB"!*;8"(",:.0G:FH#3-F2!D)31('ABA2H-A5E1;(C01(@>3?)E@-/,B8&;-#7-'?#6;F'!%1"G%+'><6*,6>"-CF9/H5;$
@r2247
NNGCANNTAANACACNNCGCCGGAACNANCAGGCTATAACTGCCACTCANTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCTTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCN
+
*#*&'#!!*'#)$*'"%'*%%")&&'&&#$)#$("*&$$*+$!#)&%+'#)"&!'##!%%"###)%&!%%($'%))+**!($%**")*(+#)%#&"&"%!+"++!)"&&%!%('(*%)"(+""#+!
@r2248
TACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAA
+
@9+(H7CF(AF;G"A1+G(&02.FEDEG-#E=1;.3*+&"
@r2249
CGGATNGCNGNCGGTCGCCCAGTTTTTCGGGTAACGGGCANAG
+
%%*)*&%"'$"#)*!$!#))''$%#+)+'"#**&!+!!%$+&*
@r2250
ACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAAC
+
3.,H#H3955/A92(.>9368E?)C/726)8(,<7<9)@GH2-G:<334(E)(:-@*$A6/">A7H")$5#
@r2251
TAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAA
+
E+68"3+>86642?"'GF*>3,)*,>+(GHDHH<-4%#(8=8<5621A2!-G)0F:*9$@:%B:=D15GH$E86'@#5(3,+6
@r2252
GGTCGTTGACGACGACATGGCTCGATTGGCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGNATCTATCAACAGGAGTCATTATGACAAATACAGCAA
+
0G,#)68!0=8(#'C</C8%H??>,:=4"H6G-G9?0E#?=2'8!:=!%@65/#='73!>5.>4C""/AH/@8+)8)0)27B5/'@<-=7C&66:=*8$E=5#%%(HG5'=%.4;%"&6./948-!8$/..2#G-&%!9"5CG<EC)))48':*5$/@*!
@r2253
TTTTATGCGCGCACGAAAAGCATCAGGTCTTTCNTTCGAAGGGGATCCGCCTACCTTTCACGAGTTCCGCAGTTTGTCTGCANGACTCTATGAGA
+
)+$+$"'+"))+'%+*&"+*"!+)**)&#*!)&'))$'+""'("%*+(&"+"&*(#')&+)+&%$%&#$+"""$'"*('!&$$&"!%+"*$%!%$
@r2254
CCGGCCTCAGCTATTGCCCGCAGGCTAATGTCTGAAAATTGAGGT
+
/6;9&4F$EE4'!7A$G8#2"E.%FFG.66,E.(-?-G?(4$?69
@r2255
ATCAGNAATCGACCTTATTCCTAATTAAATAGAGCAAATCCC
+
/&/-#24(?3>@"%1?'5GBA-?>2$3-<DC5-@"';=5#C=
@r2256
NGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATA
+
"=<=@"&H<F9;EE7'<(3'C$+1'/HD,:=-E;>4@D"*?
@r2257
AATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTNCGCATAATTACTCCTGATAATTA
+
;-'<)7@#@G1(8A4><0C&,'$H6H0D=?+BG)EB2.;8/E+,9,@,$B6<2GC%*:GD-(,HA*6=G6F:G+#:+C+9>
@r2258
GCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGA
+
C9C4;>.3<H<39?G=,5H<9@!0;<'A$B;2HG!/F&1)A@11H<,5A2F6BF03@A//@&(!,7)9C**G2->)A8,
@r2259
GCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCA
+
(B<B)%D-=?<?*"<"A";9").C-1/9'.8#==)9+3$9GC.H7203.906%#!(/!)C*7%BEC&@05?;;)0/,%E.%>EE@,$!&-.<=/36(</,1%2&;<!0+'%*<<#9:7(4C&!8'*)3
@r2260
CGCTTACTACCTATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAG
+
*<6,'2E!&.'6;*C5?A.@56+D:5C''>1-CD32)>C@EAA<?<!:'B@)%.=33#3*0&;(.D>@<=AGG&"HA1<'>&'4-:=4>;+4?)<>B';.8!=)9/,484"
@r2261
NTGGCCATCATGAATGCGATGGGCAGCGACTACNTCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTNGG
+
%"+%+++%%*(*)+"#!+%#!'$#*%+!"'(&#!$*!)*$#+&))*#!$#'*&&)'+&(+"&$#$&(&)'&(()!)+'%%#)&!!&)!*($'
@r2262
CCCGGACTCTTTTTGCTCAAGAGCGNTGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGC
+
+%'?.63F#%F%/&;<2H#!A2&&/@*H$3?4G46"D+(="+;1%43G9D$!'G,F5+"&64C$H!29
@r2263
CCCNGACGNTAGACCCNCCCNNNANNANGNNANNGGCCNCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGNACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAA
+
#!!&)'#&")#$'")"%$!%(!$&'!'$'!"&$)#)'!#&$+##+)#('+)"'%"%$!)%)'#!&&'($$!&)")!(%#%&+#(!"%+***'*"#("$+'!')('+%+"+*)##!*)'*)+)#(*(+$&(%'#%")*$!'&+"'*+')+!("%))#+)"'%*&(+'("&)&#(+#*$*'!!+
@r2264
TACNCANNTCTNANGAANATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGGTTT
+
"'%&%%!#*''&$"*'"(+#+")"!!&!!!"+%*(#&#!!#$*('$'""+'%&*)#&+$!&"+'"%+%&'**'%*&*#!)'"!*&#+$$(&)%)((&!#""(*$+!(+%&('$#+)#((*$)((++"&"+(%!&&)"#+!*+%+(!(&"()+'&)()!(*)(($*!'$&$%))$%!%&$#%*)*)%(''+'"+*!)*(%!)#*((
@r2265
CACNANNTTGGTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCNACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGNAGCG
+
)&%"&$$"#((*+"(*(+$'(&)(&*'!+#*"$***%!!&&+!("()+#!#%+$*$%&("!$*))!*)(*($%*+'!#$&$*#%''###"$!')''$%'$#%(!%'"(%)#+%*")&*"("+$)+"$"(&+'(*%"#+!*&!*#")&!+!($)*)#+!%"$&'"(!%)'+"#+""%')+%+*&%++"%)"+#*&"*%'
@r2266
GTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAA
+
:(<*$;")>+12G+#A%%1%@G4>+;#&=$30<+<+#+9:6C8
@r2267
CTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGNCGTTTCCCCATGCCGTAGCGCGGATGGG
+
2>%"4)<56E60#4>/<(</*>ADC%5E/@8B#DE?"8C$-"A55CHC(7F'5!*&&6*"G((#!H,92'DB;C431,5/H/3/C!B'2
@r2268
NNCNAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCANATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATAC
+
#'*!9D4:F;?-))G>*738BG23.$'+%?-E(";*#"=5!**F,=,A?(C/51+7;;4#3)!FA*2;4?00(?3,."2DE))>-0B/9,#A,52.@)0(?CB
@r2269
TCCATGCGTNANNATTAAGTTNCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGAGTCTTCTTTGNGGCATTGCACCACCAGAGCGTNATACAGCGGCTTAACAGTGCGT
+
!*&(%$)'$"")#((##%*$'$+''''$*(!!'+#)&!!*")+""""#'(""'')%&"*+!'*(&#&'!&%$#&%"#"$"%)#)#")!*%*(*)#%%$#)#!'('!'$!"#'%)(%
@r2270
TACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAANGCTCGNAAAAACATGGGCTGTTCCGGGTGATCCNCA
+
<+".&F#D;5(.785!7><&E=E),C$/$$&1?>?;@02F&02/)66C:AD<7*E?@689B<;=6=7%8C8=-%#39773;H5/B3/#??<;E+96A+D##(2<D-*-8;G3E.98?<*
@r2271
TNAGCGNGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGAGACATCAACTGCACCTGATATTGAGT
+
#!&"!!")+*)!#'(&"*!*((#)%"%'*!$!'+++&")&%+&%+)&#'$%$%&$%+$$($"$#&&&$!!&&*)$&!'(*$"!*"%"(#')"*
@r2272
GATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGG
+
(:3>+F5.3E:-7/9=?#A@-EB6#'B"$+5)?*%4%(/?>D$&"@007'$#$"A06=>4H@#9.*(FG6!-34?:,/A*0/
@r2273
NTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTNACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTT
+
'&4G9/0,,C%@@+A3)6+5<$2%1#06+G:;,=+=C+0594@+;2+)"0<9:=H)E$7&"('+*4/:!5?72;C5H*D4%>$0?'2@:#8>>;A03*E:C5(5#'#56;%(2D-/#C":1?F?,!0A'+#-6."'2(G?&F:?1;+;A8E&&:D$1+8A-@F:4
@r2274
GTGTGTTAAATGGTTTGCCAAAATTGTCAGATTTCCACTTTTCATTTAATAGAAAA
+
D)B+G04.1.#G.#44?0,$)/@%1%;,2-,77&8G<51G$.8=E93F!:EC,$=(
@r2275
CAGGTAAAAAGTGCAGCCACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCA
+
>1:(,?;"EG6&).-CC6H'0F9F6)A,BD-@",C5<%G?,(<("/819#DDF@)$(9%/B7,4F&.<2,F>'*<6:>,("7>B0==)
@r2276
CAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCNTGAGAAACCACGCGTGACCC
+
)!'*$*'#+"'#%(")&+)$**&&+$%$$%&&&%")*+)&#'"(!#)$+*++#&$&$!&"*!'')'*"+#*")+(*#!+&(!*((*'*(#'%&&'+*(!(!&!&$!
@r2277
GCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCNACTGCCGGAGCCTTCATANGCAATATCGACAACGACGGACGCTGC
+
/C,7)11@(=*35!($-'0)7>!H-",BGF>$%*2"A5:8D*B<.H-(C=6/991C"$.6+8&"/B.#B($>B80EH5#<F';-:/-%1B4,-,.666(-%')+*>'C9/*3,$/33+3@,7,&?+2.?
@r2278
CATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCA
+
A.,$)E:D.4$4B=2"9<'*7-0=:35H'3%.0!&DE;%;HC?*B5>+;!@/GFE=#(=%3%%7F,85*??(&>B
@r2279
CCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTT
+
B4(=A4.E=C-(&A!?>EF2>2B#BB,AA.!3H5++!9!'7%79)(4;2//B(4";-4764A25,/)5-?!H,4*2#+-.+0?#&/90A-3$&'+H.-#&8+*48
@r2280
NTGGAAACNCNNNAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACGGAGCCTTCAATAC
+
'*(#(*%'$#"#%#+#!!%#&#("$*&)%')*(*%(&%!#'(")))&&*))%#)##%'")(*)'&(%()&!*#(+'(!)*"*)#***&$")#'$!$)($"+'&+!%&""#')(
@r2281
CAATTATTGTGAGCAATACACACGCGCTTCCAGCGGCAGTATAANTGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTNCTGTTTT
+
8)&"(5?.34/%2/@A,"+??F:7(4<2@F9<3:D-)1E+>+-1B:H2',46+C/D59B#DBBDE#1C1+@%;0AA#%,@6B50H6*7G".B%"?1H45*1=E
@r2282
CATGAAAACGTAATGCACGTGTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGC
+
:07.'-/$22D$=H7?&?(=2'$>C:+,)-$A3):;FF?!%$:1(0@%05$>,(/H8H00)1(?H,
@r2283
GGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGTCGATGACTGAGCCGGAAAAAAGACCCGACGATA
+
5>.F/;458(A6(4&98%3A(-9*1B,1B!E/50/B3EG!><8BG&".A1%4?:<B&:C2C11GB&F5%1H*4F&<%+A
@r2284
TGTCGGTGATAATTCGTCGCTGTCTCGCCACACGTCNTCCTTTTCNTGCGGTAGTGGTAACACCNNTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCNG
+
+&+**!*!%)#'+*!'+'%(!+#&%)+((+&!#+%&$+)'*+&%(+'%#!()!&%*#+"*'"''%*#)+&'$&'+#'(&+%#(&)*%"'#(!"+#+*+(#$&$'"))$(&(#&$)+#%$(((%%''$&+%#)$+&&*!$+)#&"$"))*!)""&)*!))&!&%!!+!"'*+&!#!
@r2285
GCAGTTCCGGCTGTCGCCGGTATTGTTCGGGGTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGNCGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCNACGTCAATGCAGCNGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTT
+
@(477:?,.$/#,B+C(G!$1@!,E74.>'!)/+-!HH648>00(82#,(CF++2)<3#*A4C"0'F17A<-:;F:E7?;H;6B%>17E/<5/73%?)"%'@8>)-C.><;!1<,2',375E72(C/'A2/%45'+#)G,!>2-'/)==*!&)&<DBFH*@G:%0$,0H6(&<)B$,9B6A%,6-017,1/1*?,:17D7@4D$?#(5#+(25?:!),@3H@2D+"0C:>C6)
@r2286
TCNCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCG
+
%%!+))$)&''!(")')%()'(+")#&$""")%#&(!'!%(*$)*!$'*&
@r2287
CGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTGCTTCTC
+
;*B>61<)34&2E=/#;#D&(>8B&C!D'(@473/+($31G38)G29)13#
@r2288
CCAATACCCGCGACATAATGTTTGCCGTCTTTGGGCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATC
+
BDABGC40+!H$+>:+-6>+H29/HA)H#33EB5-G#(*G:E=4-A(/D;9;?312.*%72=H7<65$;F?-&=6,&*)-6)E
@r2289
TCCCNNTATCANGCATNACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGNCCCGTGGNGANTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGNGTCTCATGCGCCTTCTCCCTGTACCTGCATCAATG
+
*%'$%'()**&%%*&+)!$%!+&"$'%+!(&)*())!""$'%#'!+"%##$)!$(""(%&'#%!%*&"$&$&%(+!+)+)&!%("#$'#!*$#('&)&!+))'(&(")&$'$(#!#)"'"*$!$!%&*!'*%#"%%&!#''!$*'"
@r2290
NGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCNAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATT
+
!F%H-&4#"$<"&8./$E.;47,B257)9.)7>1G)("$3-FF=#294?4A+7"(8+:))79:B2)5<9,6!=4"D3.+73DH)5>94+9+F($&!!//'4',"D1:+/F<C$+
@r2291
TNCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCANACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCNTTTGCCATTCAGTTCAAAACCGCTNCC
+
(#)+$%%'+"!##*+"%&!$#!'"!%$'%+$*$$!#)%)"!#*+*)&&"("'+'&'**%"$*)+"!'$'(*)%#*"+*+)'(!)%#'*'((!*%"!)"#!#$&#'#+&*%(&$"$)+
@r2292
AAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGG
+
98:=0@+,8<&2>#@/)F!"<';:8;5)6);A72@2C899D+EC./&8+"#1H+##E$E:A".()8D)1G>+H!9$4"B8!%<E*
@r2293
GNNGCNTANGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTT
+
*&&)*!*+(*')$%"&#$)'+)+!)&+($%%(+&!'*)&')&%&)!"(&#')*%)#'"(!%*)#)#+'(%*("&+)&"+&*()+#++&%#"*"'+"!%!)'$(+
@r2294
ATCGGTTTGTCAGNGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGA
+
&=H%8BE+@3<;!62C4F0%<A;=;$'80F>44(+2!>E+>(H=D@A+<6@B+4/*D"!4)=?-,5&'08%%%6$-,8B.3A>6!<FB969,02.@*68>??9.DE1&@+0,G#H1D)=*F(839>+3HFB>0CC.52>A;2)-"C40++!FAG9B:/<237(+'-F)GC&:F;D)2-&2/H214-.(;A>C8>@=*#G*9>6;@
@r2295
TATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATCGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAANAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACANTGAGTTTATTACAAATGAAAGTATGNTAAACATTCGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAAT
+
),9+/*#G/4,;&@E(E2>2*!#6?9:/D2"B1=/</*02%;11"/)0;/=51-(/(B;)F?/27B,F@:=&H6A0C9/'C=<C.&/G81?96;!?43:4)B*2)1)<$E#1!';"@B(HAF5.59,#H.E+3%5-;HG)D/282=%?"-2*GF6.5!=#1BA@:F9*0:$BD,+!0)$,:6)(&+B>(*D!==:.B/A->@>";04$!$CGH,:,G=9:$62;.3.3:5C%2-:3+"$D3"=-(1?!5E.'!%#G8D$214'=*8#$2G#19G,254%7?0@.)*6;"';!,&.6?">1!"
@r2296
NGAAGAGTGGTGATGAGTTCCTGTGGGTCGACCGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGTTCTGCCATGCGCTCCTGAAACCATCGTCATCAAAC
+
"+)+('!"#("*$$+(+(!&)*()#$+'#%%+&#*&""(!#%(%#$'*!($'*+")+!#$$($((("$+'#(&)$+(+&*(%)%+&+$'*&!'(%)"#%*'%)"'$+#!(+!*$#$#$*+)*+!*&&(%#))("'')#*#*'")%*%+&%)''+&'(%*"'!+(("%'+$*#"++&%#)'!#*%"%&%(""(%$'"
@r2297
GCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCNC
+
=&(%E)&C#.+AB4#F6E,:HG'GGB(B#HEF34&9?-88":2!"F*6=CF$G"C,.F#.F:7"=1+CD<'.,)>7(4'$.@02"CH35H+)!6>/>B8>F#F,E88)?D642A*77:)@=*),?#@9%/;'#?$."*52';D7'$"-;:@/7*=91,4,AED(
@r2298
AAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTNCTTATCAGGAAAGGCGTAAAT
+
+!+)'#(!&"#"+&%#)#$"((%('"'(!%#%#!#($&%!)"+'*(%&%*#(%$((%#$()&")&')%((+!"%+!"(%&(%!$"##*$('&$'("&&!"(*('"
@r2299
CGGTTCATCGCGGATGGAGCGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAA
+
!3/H#!$;8%,#F;E7<3*:'<6+<>7&%>%1AD1F->96:+/085'=3BE5>(!0C'-33"7;>.$3
@r2300
GCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACNCAACGGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCNCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACAC
+
,*3GA3:%D61A9>86B,/F)B#)3G>3-,=#H--.,$F85<F(D'8#E@*2DE2B%&34%!>C(A6;8,&<?'>DB"*3=C.<@A')70)2@C-.9:3!'.7%0B%#!65!G".:?H"D<D/%=$"C+88$C2G9;)?)+C75<)H-$#/E(,C)AG3E*;">1C+'%:);,H:B#1/C4/6!1B&!&@7=F=:%F=(A*#F@E6)39FA6?/;7.950A('//>B&E<B4H35D-)E?H0(+>-/$*3
@r2301
CCCGACCGACGATATCNAAGCCTACGCGCTGAACGCCAGCTGTGTGGT
+
>3-$8D8C);2%=&00E33$E75*3#.<G3',!E<A4#8G%(($98#D
@r2302
TCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAANAAATCCAGGCTACTGTGTTTAG
+
F'32-7*;<=?;8@$==+*D()C,%$!-!!=-&.:-8#:%B:D*5=/0>::"C5-"G,$F+>+&0';'F:;57D/+,1<>(!CF;
@r2303
GNNCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTT
+
*!"+(*%$!+*"(+&*%)**))"'+#)#!"##$%($')$!$+!%%'+&)"$%)+!'&'
@r2304
CATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATG
+
C6!:G)E/AG*!(,#.E+*>;EH9FG+:3<"%8BA=+:1)6<A@:(7>,BA!=""4"F$F(C7D(4@+FE;;3;+
@r2305
CTGAATATGNTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTNTTGCCTGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATT
+
'$8,(9"#.:F4?2)E8%6@;G)FEB./$B;@@9'A"F!DA:2;!+1D0G-?(/5G(#'"7"*=(7=6(,7G7*5H.50'*&A!FF5H#((++1,+19*82"@D?"='BGH<532:0((B$,@,6))=@?'&-E@+:&0;0FG45:
@r2306
NCCACCANGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCANAATGGA
+
"!+(&$$('%)%++)'*#)"%)#%+#'%"!"*"%*("(*&#"+*)!($*'#)'(*'!%"+)#)'%(+)#)"")+
@r2307
CCTGTTAACCTGNCTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTNATGGCTTTGATGATATCC
+
H/1G>##,7&B("?+?&<0.3>E/!5#*;29AF=%H=%/9D2)-H>:&"-2H,22,&7H#5A@+&6<$.6.'846:.#!5+*(H;%C%!
@r2308
ATCATGGCCCTTCGGGGCCATTGTTTCGCTGTGGAGNAGTCCATGACGAAAGATGAACTGATTGCCCGNCTCCGCTCGCTGGGTGAACNACTGAACCGTGATGTN
+
H7H'8=(:::A4,'5$4F1#4"E938+++D$,","A&,#,*;=7?"D%E?!/:66C0GHB%D%B0<,@=.E(3!'/G$"2%=72&9AF;@4A<!AD1G4H2F:*>
@r2309
CTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGCGACGGATGGANGCGCCTTATCGACATACTTAAT
+
6.E6<..(D-G6D*2"/G(=@8#98.,9BEA=8/$=,25!C'@9=55;$22G.!06E!!D?EB/==79"%<>75:DG-)
@r2310
NTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACG
+
$F'C)3;+-!30FF%-,/99@1"(3$8<;)>9%3)!?B@%&:9+
@r2311
TCGACCTGACNGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAG
+
&+'01@@@?"++,(.E*,1:0H-(589H@<),<8=(GFG,9-G'1?!.C?+;80/%#)?"H4!=2'C?4&=<6#>E-'7"-54"$'B@'*3,@*%
@r2312
ATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCA
+
5"HA)E1(4.05H-6$524#,7@3%7!<0)'6%<D>/9.2HC+*7B%G66?#*?=&&'43@7A(11$G0A*A#E9*!3C.
@r2313
TGCACAAAGCATCTTCTGTTGNGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAG
+
)D#/!--F#B-HG0,HA'':9/+C6!>10C.FH@7*$;,4$6.>'>8(::G.&377?C6>A111*)=E-HEG/6GG</:7E$,C2$"G>$+=24H,!H2$=!(D9>*!+(6%CF:*G".8*%'$F:<+0E=8=-1BD3@?01%$.&0G(:>@2A=<C6!;&12ECB+B>@!
@r2314
TGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGAT
+
+"'+"('%'*#+'+#*'++"$'%#+"*#+(*$%(#"+%"!+('""$$("*)"'"
@r2315
TCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTGAGGCATTTGCTGCATTTTTCCTTCGTGATATCGGACGTTGGCTGGTNATATTCATCCGCGACAGCCGGACCGN
+
3%+4*?%G!)*F&5$E#49*=->B.?:7$9,,+F>)&F*)$@>3<G@>3C1@"FH%B/+D@@'==E"69BDF)E*.<C)86,7C7(53:.+%?8?4@D)?):9D)=@(?1>3&=D2(@=?1*04!58:2E@7;?;"@@F<!9$(/:?.(F9FC7H,>18@#A'E?D'HA68&*
@r2316
AAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATNCAAATCN
+
(+%+&$'("''$!'&&+*"'$((%!"'&##!+#*&$&+#*(%#('%'(&#)+%'')&'+"+)")''*&))"#
@r2317
TGTAGTNCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCANTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATA
+
E8'"8-*-6+F@.$00@5526=D?*8F<A'-B2$8$)H5B3H=5@$0'29A:5EAB5:%9@'(#078-2=AC+;@-CD"D0%>83;=C'=66$BA=H
@r2318
TTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATNCATTATGTATTAAAATTAGAGTTGTGGCTNGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGAT
+
+FB.#/-9EF)73=!7?+6&;6F6.".D0;<-46.->1%EB'):48&24?,0+,&(4;D0(*>C#+C651<&7<##@462F@0.-'%!$$B"=(B:>2B(*%7/#A6#&8(CH<8>H?4F%(B*$/5((9,$3DB(D%//E$$C3?A=G?1,%E#!=F(9!2;1&EA<%:'CFB$%B+49G!B-+A:86./7%,H(-GA)$-1(*#
@r2319
CTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTC
+
F-2.=(/C0@;25!=(9);#6E%7B!%-"8EB1&6&3=#>D(A/%B&,F,5D$<)#3F3>"'9*1BC8!
@r2320
TAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAG
+
9*9.F!4?6&3%,,B9-2)A0C826B)14?"%>845D-2,&B5E&E=/''A))'".@@29"'
@r2321
TATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGAGGAGCATGGTGAAAAATGCGATATCGCAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGA
+
-#A7:..%*>)6'2"3<"DB/4GB8"F6H+%/A,4,60D2):>(=H".C895%85'9.5F"/$>,6G67G":3F857;0*!H'?&.*=<4>;?7GB3(/;(="2/!E(A;)389=$H-C@$;,F&%G2&G:G79./&>8.7$-6!9"'!)@@42?>7$2!37+74@/6$H3%*,!F#C$D?:!83;G13
@r2322
GCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGNTGTGCCGCTGACAACGGCAC
+
.=*BB,A,"DE(:!D<6&*(H.B=2FE)@*,"DBD==E-)3@,CAB4&/CF571'?'A#3.=*1>/H-77@5:=
@r2323
AGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCC
+
;EFDG,A))A)$#2("&/4-,)B,H:!2>291?09!AD*=04="-?
@r2324
CTCTNGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACNAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCC
+
*""'!+!)"'"$""#'*!(%%+&&(#'"%")&*$(!$!*$''#("")$#(&&*)(**+#*#"%'&$%#%'+#'$)&'$(+$!+)+)#&'*+'+%%!''"")&(''!*(*)((**!%+%##%*(#)$&&"$!+)+&
@r2325
GNAGGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAANCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCNCGGTGAACGTCCGCCCGN
+
"!HC#42%CF&$$8F&)<67!#DB&!/#*3@1)527&!A2:$0-97FF:1H%E,.04!@)!+*9;%9E2/,&C(,*<!(+>1-?,?"(=)=253,D==)#H52
@r2326
ACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCNCGAAAAC
+
%A%&'7.6#/<&$'+:+$3H>-;/D1HD%.+FD&*1=):4:9)!+-*A"/&1'5H*E!))44&&4.
@r2327
TTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGT
+
;(H'DB96-61!$42&(6*A)?+&/7FG7'@0(E1+(5D0?F16A'EE$(?E-?>:7(,3(/9!A+%;.A/6C6#("&C&3");D(
@r2328
AAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAANTCGNTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCC
+
+&*%+!)")'#'#((!*$"**$$*))%%'(!*'&'%)!$'+#%(#%++$'!"#'$$)##+'(!+'&!"#'&+($(&&#)#*&&#!!!)*'#)"("#&%##)$"
@r2329
TCATTGCATGGGATCATTGGGTACTGTGGGTTNAGTGGTTGTAAAAACACCTGACCGCTATCCCTGNTCAGTNTCTTGAAGGTAAACTCATCACCCNCAAGTCTGGCTNTGCAGAAATCACCTGGCTCAACAGC
+
$??B*C)8.0H(.9@=-F>-5#?33>'.0.'G7H@>=D>9=>.&91&GDFAH)5:3/8E;<<C)%.+%67=4A?2C-0(4*7*(!0!6&&F1*%C2+$&F64'<$6>+,-5>)2GG0(<908$+70HE)+BF"5
@r2330
TAAGCAGAATTTCTGTCATCATGGACAGCACGGNACGGGTGAAGCTGCGCCA
+
62=76(&;$5-(?9@BC%4$'%/+<:<7<%BDE78HE37!!4'+?;9+*8(B
@r2331
GTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATAT
+
5.D));CBA9652F*D#/B*CA+($"20;HG0'/:*'31%:%++8HH
@r2332
TNTAAGATGAAATAAGAGTAGCCTTTGCCTCNCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTNTTAGCCCAAGCC
+
+A::%-(G72*-#&<""319E;0F$=>-6$*@!@'0:6@%0C12:"F4&'.36AD'>3=,GB0<2.6!55%,;68/*=1<,*:!EC*#7522
@r2333
GTATTCGATGTGTTATCTGAAAGTACTTATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTAT
+
859<+92:-;#<8*9C.*(F:-?)!CA>1:H2&DD+"@/:3#13@"9+H2F%/64,5!7)"A)%.HE>#1#&$@8,>(:48)'(A8;5A!=)%HA'-&0,1/?*#*0)&+.))61B4*++"*0>"7*5039H9E8?$=D%5,G>61F(C8=</-?)<+3E=5$@$/E84H32+0D=)8((%*0#E*9E?/5A=&12@D<$B<$>
@r2334
CACCGCCCGCGTCCGGCTGACCANCGTGCCGGACACCNTCAGCACGGCGA
+
$$+"!'*$'$!*!&#&$+()+('#(++'"%%)'(!*$"''#(*+%'!"!%
@r2335
AAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATG
+
$2:D4C)CC@D"&H7,-3$6!72?9%A'?&A&8?ED+??+>%1<=,#B!55$)-9D?:5$>$"@;?"E26?$<;-F-G0D?+1?AFH(9;*4>%
@r2336
AATCTCTCTGACCGTTCCGCCCGNTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCC
+
20B6%E)=G-,28%3=;>C40.<8@=08D51;C9;)F>9E(1G?>74G$G1(%74%/A@"%.3(%:/!*/HF-<;B11E"C<2F447A+4@'?!A7E>96*9)-53CAE"?9*A4B"#A6*=.1
@r2337
NTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCC
+
#72<212<@BH+>(+4C.)4="+:=D7?C(95/$54G%+3*)BDB-#
@r2338
CACTTTGACGGCGAACAGAGTGGNACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCG
+
7#6@$F#!8(F;"25>7B-?@>F@A')5=!(HG5C="?@AGG4?.(H#@!H)20,(E+GF;0,"1>68<21)A7+'=B;/$=**'G2>G&!#5B*7*+*+-$C&H./=
@r2339
GCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGANTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAA
+
B90=F7"DC5"B4'0<=)6CA?.GF:E:*B*!?4;;'C-",*>@'7E52*.;#;8*<@233;3/@1.BB7-'7G$*B".:C3.;4#*":<9.0"'19<G;?%G
@r2340
GGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATNATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCANTCGAGGCGTTTTTCGTTATGTATAAATAAGGA
+
9B1,3*>3+!F+1B/:A,4@;"-#,BG4DD?D*$0%,,EG)C.4A??H>-9(B#92-(5E@F=&%>D!;+7=4<;75)6>4C!$(D.";,0B*"9)0?FEH1%A<69=3(F@B=+/@:C-+E<G$B3%<'H;$F8$;80>3=)@;!1@;=47G%&##B6/
@r2341
CGGAGTAATCAGTAAATANCTCTCCGCCTACAATGACGTC
+
$B:92@&@8,3BE:E3(3"1,;--5@%$F&B46A97,'+.
@r2342
GCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTAC
+
12=A",7H(125<?'.C?5@8(6/'%4H:#C>'%,$6*6E/=+5,"$*.AD5.':?<*F",E
@r2343
GATAGAGCCACTGATGAGGGGAACCACCAAAGACGACGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGG
+
>!1:5'!8-/3?993A03!*&/<%18>BF&5:A+?>$E<)C@?E@8;!;3;A>3/D$(,3&8C;@<7,H67.*&470
@r2344
TCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGT
+
70?1@2G)E30@C21H%<?8+6-,03;3F<.01E?$$D@%%B0&3:8.H9,A%(<:(!@,A'F%/:(*&/G)@2G4;E,<4
@r2345
CAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTA
+
0=8*:?!%!H61%.8:$/'5.5D'-5;5EF0G'10%-06/(&>,$5*D8-,BG*:!(-$F6E,.7E(@6G5$48;=;+1A0;"
@r2346
TTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCNCTATCTGNCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGC
+
94,8<-"-#:(/G:(,4"(;'0+30$.A,-;;B9;&??C>;F9#%<5F-#<)H'F7;19#+=H<DF*8?48E?;0*?=36B/?&#4.;@"0-2&<AG5;*=6&;:(:=&1C56A%%=7(8.=&#);>'@3(D'.A;,-EB1E7H+1&@B,C51::$.B!G(E+%%9E++#(3/);&86BF<,?A'3HC4=C''HC.
@r2347
NCNANCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGGTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATNTNTCAGGGTTAT
+
$(!%$+*''!((!')!%*"#"**%&!%&&(*)$(#%$*+(#(+"'+%)(!&"(!&%')&')"(*#$")*%)(%&%$*'(#)%)()+*%)#*#*("*!''))!$"+&$((*!)'))!)*'+#+#*+&!('%&$
@r2348
TAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGT
+
#4(&D:C=@#1"<&9*$#+&%?200!:H1GA>CDD"0$0*??)355+,*%F-*&?&1/:,-FH@=)/HC#*-D-(@7<<;2F-?27@A5852/(H?BD#C-
@r2349
NTGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGG
+
#<>0":D8%HB;:<=#(;*D1H@0>=C!)%@)D%9&#0B@EFD.>3D@A7?!-"E"&DF/1>4H/G2'G.-F?'DAB'8);$9FH4EBDFC&);$+,)4A79<E&;50G,<;-2@@.:@7B6(<
@r2350
GTTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTG
+
!H!;E'8&?F"4-:,22@@G19#F;/3?*G><-)C&2?)C$6H<G4)",,50H):A'#,.?&
@r2351
GGTTATNATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCT
+
*A.%("B,214/%8@>,+)?*=.@AFEF-?F=D8D2AH*F->C@CA79+56
@r2352
GAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAANCACTCTGCACCTGCAGCC
+
AG*G8F$#$(5*"9D(;+)/!A/@!C/>1C07'4")=@<4')282650/%DD@%1@&2FA&@
@r2353
NGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAGTGC
+
!140B#.:%-9:72@/7F;@%5%!#E0@$9:$,F+4G2$9<%+B;??E%%:1-G)H74=9=!C4<
@r2354
CCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGC
+
<:192-66F(HE%G,#5%;$6/+!E,$:?7DC>%-.6%E8,>%$!%E)C*5G"#>9DC(>D%H8=::051D0)C!G(A4;A26G+?G@C
@r2355
NCATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTG
+
!#):6&=%*H@D/%*?.F,,1-=A3*$:%9;'0F0,#%%4+)/2,D8E?4,D51;@8-8(D!,4.:C480"C.>+$FB9='+971):<#1:"4-D'A?588C.
@r2356
CTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAA
+
-+@FF:;02>6E"-.D/E1*-.,/+99-&4&7?+:GF#C.:A&96GA@=+D+@"99#A/D73
@r2357
CCGGGCGGTAAATGCGTGGGNGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTNA
+
BF>#F(4145+835.7+F;2'<"-#<>.<$)C?'/)2(*.CH,0+;,@D&+:$>2E/99H3+/1G3G'$5-3('@06!-E?C@:8-D'G73#=0F)60@%-<?6199#E6&,=/8@:BD(B7F2@(A&HG#,&B=+.E/A+20;70"8G:3<A0D-E4"
@r2358
GTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCT
+
=E838"85$D*,B6B(<#?A09A7<.(=;G"=2H%<ED4=33E$-30%,36'2H2+4%@6/A=0%(87;<9=D&),C$F,C'+<G9D?*?&'B.+#/#<E(@:B$03"$0:4++"+,$G)#;$"2:,H*>)=219C3.F8;>7)C'&:<BG(0?+(:2;A=37>,G5<-1F>B&D
@r2359
GTGACGGGCTNAACNNCNACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTAT
+
*)&)*)%$)'#('&&")!+'%(!&#('&("!$'#*#$"$#+*&(%#$%$#!('$'*
@r2360
TTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCC
+
-0?7(4"/EA:D0,D9C7G@+.41+$=',-=6/))*7'?.C&@3C(D+&+!7.GH,DE.=<E,6
@r2361
TGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCC
+
(4A2@7=H;H/+;*6+E4'(GC4'71"$<&'?E26#?"<.9<75+8@GB3""*D@/6
@r2362
TACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATNGAAGATGGGAA
+
5,760="H4*G!94'3#G+1&#$EH-;CH57#7@@-45+C-%*.4FE/410#/6(9A$*@1GBC5!09$FC+7(+5.C%CD"B==5%#@6(6C0/40E$&?*./C9*C&&'D'2E/>
@r2363
GCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCT
+
5=$$)/?+,&:4F:,+'-F,G@:0F9'B.<5(4(D+!=;=C5.%*4C0-04.?C5$78?4@#H'(*C:)5/@FG6%=::5@3%:2G='&<+#=-/100?)(F?+!@65
@r2364
TACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTG
+
,G"GH-+':#3)B1?@81.-+@2*/%0HE362->9!$1!&-=8.##C;/=(
@r2365
CTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGA
+
-@-0=:+6-8@A21G1;GG.!:(0E&>("+6.B$6A*!=(<F8/,8)7<6E=*/!@'-*))9-!%=.5'
@r2366
ACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGANAAGGCCGGAGGATTGCCGCCGCTNGTAATGGTGGGGGCCGTCAGGCGCTTCAGG
+
H=F1></*33G">?,0@("!BGF;9:+-7':9@*/>!+3$+CH7H)!+%?9*CH"7,-2#);3(=4H@+(F%-A?=6<@:.*H10*>>GF"&9=:)$"C;F5"?108+34!
@r2367
TCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCGTGAATG
+
9)GF+)+;5H"4?@H3H(B8GG0*81@D++90H?$.22+"$><5HA&'/.H;=4!?577*2?,=+/<9=BC,F2A24:>,?6!#"C1%,<41D0$F!H&!3&F+GB5-215,"-!/F5;+7*-D.#-A@<54?/0,=0/D63:>+"H=+?(H73>@8B)D7=#-H$H/=;H)*(,606(?)#F?!4
@r2368
TCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGCTCATACGCCAGCAGTGAAACC
+
>H?1<D,)A/!E"@EG:8=!F"&9'5A,G=+4"G<#C#6$H;H5)F;%'"H,:65)%H,;;?D!;"G6-5&!<8
@r2369
CGTATCGCGTCGAACTGATAAGCCGCATCGGGCAGGANGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAAC
+
./H$:+*"7&.,@*6C!7G-G?(8<%>';$,5D%+),(0=#3DB?AH%.43%1?9<&"))!0H$17&'C)/)4GE9(2D69E,)1;$BD3:919885:(E&C@=%C!4D+/,G7(;8#5*1H!@'4
@r2370
AACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGNCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTTCCNTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCANCAGCAACCGCAAGAATGCCA
+
954BFB@')7.;4:!FA3?E2/"6:+E8#E$?>3*'1?891<$<@";@25B0,(>5@=#8+4A9?26<G&E'H@E8AAA8E&,!55)1=8"%?3$7>%048D,=$BE*5/.;7&@A/+:$65*%*426*FC5G6!F%G/>/D.%C.6!A,:@9-(.H&16%A.3A8"(6%E6D57.1.'';(HG6=;"&B03$B'5CCB%!"4("B%)>?A1H+'=G$,G&$DD601&H,44.:+,4%$=8#)$.68'0/&4,2*7F2$3>!8>A@,/F,F+/79H6>
@r2371
ANTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACC
+
)++!*&&#)%)%!#&!#!+)'))'$""'!!%'&(+(**)&%)&!+#!'%+#'$$*'$'*%)++'"&(
@r2372
ACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGA
+
ED+@C%03-3#-,0<?0;A(83HA>!!G!0*:::=;?:$9E830GFG5HE$?@/#EH4-22"+#>$1+')$H
@r2373
TAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCGGCACACAGCGGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGNGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCTCTCCGGCGTGCTTACCACGAAGCCGCACGACTCC
+
2"<-H06A3.53(*<"8-<!3/51,@%D.((G7#7@@0H-<+G!38"(G,<@;$90<F#11)#>B?HA*DHBH.63G'3HA+17;*&/0@(5A'C7*$*=',:"4E;=E3:F8?4H1)9/%)?!F5E,*B$6(.AF-;G"&$:$+1ADH;+94HF4/E2E+$95B@)(@B8B*8C!D!DB=@:'3)+5H'@8?&5&BG2>37@HE08,'A>::391CE:4AH2D))>@E%!@,20"HB+3$-A7DB1(-6,".;?/=87&@?;6//5#>%1=8+)6/>%6H24DB)C97.,D9E'DE5*1F)HD.HH((5)
@r2374
GGAACCTGACCACAGACCCGACGTCGGGGCTGANGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGNGCATTGCAGGCGGCGA
+
;(#B!)A<!H/9$("@@8FE5?E272"-H29%**A-'>0G$#+$17!C?4@+2'4712&D7$)C:604#1F@;)=/93@%2>>9<E$-@<-4*%DD8<>@!+5C81E6",881,):)>.-</#A1:6$>"E437=
@r2375
GNANNNCCNNAGNNNNNNNCANNNNANNTCNCANNNNNCNCCTNCGGNCGNCCTNANNNANGCTGANCCGNNNATCGTTGTAGNTGANNCCNNNCGNANN
+
$!$#""$$"$!$##$!!$"$#!"!"$!$$#!$!"""!!""#$!"$$!!""!$$$#"$$##"!#$"#!"!$"$!"$$""#$!"$#""!!!!#!"!##"!#"
@r2376
TGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCNACTGCGCTGGCCCTGCTTATTACAGGA
+
>'1(,,/>B<'735>,G%">,A<#H2;%/$"#+GC=C.'-<<@@(,;#49,!H"DD(-)@%-F)3+3<$@97(7*0CHA=E&C%+9E%3*;H07+.A#A#EH"3$?
@r2377
NAATTTTAAATAAGTTATTCTCCTGGCTNCATCAAATAAAGAGTCGAATGATGT
+
!/5$.&7#"-?81@"4A;*!!/)9G+<$24#E=:<%*:)+C./9/%1>),C$#"
@r2378
GTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTGCGGAATCGGTAGTAAGCGCCGCC
+
)''+'"*'$(%()%"(%*+$*%&#*&+#'))%(&+!%*!!&%"$#*%%&""!+%+!&%##%+$"'#$#+'!!+&'!*&()$!)$'&)'&%"$&!"##")$
@r2379
ATCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATA
+
9F/",B?9<@*A.-+CH+95F,,CF97"2EE6(43A7E7CF:=?2DE4!FA5,"FF85!?1'F7H4$DB!:>2E91#+E"%)E(,$!A'.9B71#"A?
@r2380
CCTGACAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAAGTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACA
+
C//67*?%.E#0&1FD.==)E@724$6?='%.E@B!)=>/FD->&CHE"%DF*1'C7-/A84*$44)<6A/67=724H.C%,A50=?"E6B3$D'.E'$1'1-E-$&*;7&B=
@r2381
ATTTNCAGGGTCATCAAAAACANCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATC
+
4CB@3+.6=&>.-DHF>/>,6-+2=60>08EA<(>8G7&(@=F@(C'8@/=.<.3,()A=>"D2!F8F/&@H.(::E=!F93(F&1.<+7*!0+&"?G9
@r2382
AATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTN
+
4-E.,$':B@GAF7+?95B6DE<;G9&74?F<($C&FF+.0"-E6-+A'(DD*DG,%<6<(,&%>;H"75/>G.C7B(.H?:D.:$!%;A98$G$>/'<222%-04,7-/66C0"#5<.G!0/-?&1@$BC+7"-4E##:G+*93+==H!8'.--C2A-!4#C=HB32@9.A+7@-A>A6
@r2383
GGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGG
+
9H*4?45*-@?&A'!@(+<.%@/A.=;EC<*:>G'D0%4-76E8!'2E4@BF-)'!.G)2':G2(;@"-C4!>DD-9:G6C66=<!50"!++/7CE&C""E/3:D0!E=
@r2384
TAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGNCATCGTCTTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCANCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTNTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCAT
+
'-5>7*%0CH@GD&A/$,$:G7"2!09*6E8#*G4$HC=%6-7,2)/46+0!8!1@1)E;F'(CAF58$D'!C6G55?:-;>3>>)2-GD31E)E'25D<"C"0("B0H-51/0D;,D<;+&A%G"E9FFB'81F>H@4016FC/A&E;5G9;!:+*$C7$E=C7G1;>-G)(<(9-B"G9;??DH49)0?D980G.<1HGB7G)6@),>!$-A:4GB?&'36"F$H+*2,'9-#'C//E3E>5'43;;4>2,0?$0<*>9GCE.D$7B*!%,??>)>:5.BGE;:.GD/:*F"7(-6,DF5>+<!&2,B#9&->,?#*A2"40>@:)?39*F62#F#%B58*3?;FC$>.5B)C>,HD!
@r2385
ACTGAATCGCAAACCGAAATCACGAACGTAGAAAGCGCACTAAAT
+
).E!A20<->'-,BA2).$1,-#0++3E(;*>%#!?%0*?,@=E9
@r2386
CAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCGTTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACNTTTTCTATTAAATGAAAAGTGG
+
&>A'&"%>(142G*!,4**::)H&"!*:54"E)HDC'%?B&;<9H5%<%$F-.<#%51*2*H92<:1-#E)*=A-+!A2*46A(?+!*A<)88<C+$$'&8A=4,@;!B$B4=@"/@=//D%&E;H@E1)H>B@5<<"C;5B&9-";)<:(.@CA+B=2B3?!.54+A3'$34192+2%:926+:A:>#"3514
@r2387
NGCGGGATGATCCCCATGTNCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTNGTATCAGGGCAACTCAACCCTGTC
+
'1!15<0*A%53+),C-;!.8D;-:"4+%A/=('@DG57=1+?AB;:FC:C,/@349D5;>C-61-;E2.HE7<%4>;0+#B8*E+"2?$4G!%$1AE>B002C:23.B/5)8,4)&H:27H!6!&"&
@r2388
CTNGCCCTCGGATAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGTTACATGGGAACGTCAGCCACCATTACATC
+
&("**+*&'(!)'$%"+%'%')+&+*"+#!+(!!&))#!!#%!+*%(+"$*$+!&$&$"%"&&$($())%('##"%()%)!"+*+(*$')
@r2389
ATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGNCAGCATGNCCTTTAATGAGCCGCTGAT
+
%E9/<17:B),3'<D98%>"-<%&#3CH?F!DHHE.&EE60H@&:<)DF7@21;#'/2-;66+;FCD1'$D((9&?--E5C"AC!C3A',G;1H@"3
@r2390
CGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAGACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGNGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTNGGTACGG
+
3,B=(6*.!".629D92147E2(?=?639/'(9+,/?B8%$>7C<C0!#9#+A0HE)?-%-(1=#0-?&6>4/(C"/%@?9'$+4#7;)$D%-3AB%7-)7D4"4FCA?;C/+.4-8:D:-171>.;FBD6"*$C7A<C2G*9A340G:>/'4.8<+8,2!>H@9G89@37A3?A$/E
@r2391
CACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACANGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGC
+
>;+8;&;*F5;D%G"$<D?F#:<@B3@;D$G-67!D;9/1-+(FB(*$<&F;7B=?FD*5:E7,?)@&?:0G5F72(2BE@2EB1%"&H*@#>880:@&A6$;/%'A<;4"E0=#,8-7C22A2$=7(B5$A'-C,%;.;'!GEG$&1B14-$%G(/;F=4</?*"+38*;CE3/
@r2392
TTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTNTTCGGGCGCAGATCTGACCAAGCGACAG
+
(A-G)6>E-604D"$$=+213<>C#,85E2#E%B4+#$7$?;!='1.=+%65.&&*E+/?>B&'?#=3&DF!$A'1H9:4A9&@2)5!"H&7G),=;$E,7#,0G
@r2393
CNAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGA
+
@19('D>EE6D?"!GE%<*)D7-2BF)31,/$').G6B@=/;0
@r2394
CATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGC
+
<7.="*3H0G489DG$*22:&0.H(/5?8B:8<12-#1HH.'$#2
@r2395
AGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGNGCAGGATGACGCCGGACAGCACCACAGACCAGCTNCAGAACAA
+
G0:$?$3"982-&AA'H:0C3%=9')F&C6><44::H-F"="4!+8HC('*BED07ED8D'1C5B:D#!H>?1<'%14A-04=,-G&:,?A#;B!=G6:1C:H+&&;%$5?7;C-@G.+'@@711;184/5G<0*A7729F1-.=3CB4<7AC4#68:G'AD)4+06=G
@r2396
CGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCAC
+
@.9<3,@7F>3(@C)6>=(")13C377CH.D/*(=?>#A#'/52GDF@6<
@r2397
CATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGTTCAGTAATGCG
+
#332:-*G7*798A='<=>48>4/:&F7A45B5G+E$7@)EC%)D'E#G&82&.<DF@E&9(+8+;=35'$@EH=H.$%++3!997C#-H-='9)1%>5A@ADD-!!@C<7#!5#.90F.73;+-DC!
@r2398
CTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGC
+
9H>:>7G4(>%0433%&826,2"?E+%18H2G$3%>2;?+<+&/05A'0;7"*7B/9BD"19C<<=4&9/"AE@%B+0+=168@6657G*>)#="92):3E%:?/$5DG(CBG2E2D"#
@r2399
ATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGC
+
.#6@1B#94!'<BH<6@3!F'8F?*>4(G+00>.4+?5)B*H"!-AD""<A8."-(+!#1*@G(F<G&420(#G010E/5'
@r2400
CAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCNCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATNGCAAACCGAAATCACGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAG
+
7$1<4.5(:8#@<4-?0B5:&,>F%B1$G'>=6%4&B.A&>4)DH6&(:@3.G*?#HC#/A4:'!((2;"B!23,H:'074/@87'*?D=1*598&9B8E6E6CA:.%&#?G'@"<')?/8(7?=(@E&'"47.>>1!B%F?!667.ED@@,H2E?+++#F@7="(>!CH,GC)C(#(2?B(?:=107/@6,6,@/=:*<5E+?%
@r2401
TCNTACTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACAGCAGCCTCGGTATCCAGCANAACCTGCACGGACAGGCNGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGT
+
**!+(%&"+#%#'#)'"+)*))$$*+("*+)"+*($$&'("!+""*'%&"(#($(()")''#&(*+)#+&(#+"&!$&&"''$%""%)+*)"'+"%)*(&'*"$!#$&&&(+)#"#!%('%+##&*+'%*!*&$*#')""(**)&($&&&!%$&'!#(#!)!"("*%'++%$$$*%'!&#$)'!&&"))(%%$$$''*#*+'(
@r2402
GNGCNTCNTANNNCNNNNTCANNCNANNNGNCTNTNCNGCGNNGCNNNTCNTCTACGNNGTGNATACNTGNN
+
"!"##"$$!#$##"$$"!$$!!#$!"""!$##""!!$"""#$!#$#"$$!#!#!$"$!"$$"$$"$##$!!#
@r2403
NCAGATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAAT
+
"FH:/D&2D9&B4$HAD,-;%1="BD#C":74?&..!>%?*F
@r2404
TATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTTTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTG
+
$85.#8C;*=7#8?F,3:(:-7?<<<&-,&/(875?(/(?A%.((98&3>9C':6-=;&$+&4/;$D5D8?)F?1HD.#4+=$99A!36+),*"E6><>?;9?8<=F4@(19;/-8A<@:!!B>DE,
@r2405
AGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCT
+
A!+4%!528G9A#'*:BH:=CBE5$C&6'$+31!>2@2C0!0<
@r2406
ACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTG
+
*%AF5/10=?@0E(?3"G73,(?=5-6%'2%8$$C:*(A7E<=E<1639'
@r2407
TAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCAC
+
E+H!=$H(3%EBE0G>GE0H(00+7DH67DED46B1BB"*#'81*6?G(C7(4(78H69?<$$#:58'3
@r2408
TATTANGCCACTGTTTAACGGTTTCGGGATTTTTTATATCTGCACA
+
()!)!!(!#"%#))#)+'"&(+$!#*%%#$'#(")!+$&$'+&)%!
@r2409
GCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCAC
+
5B5%>="-F96-9*?@(E0<A"3&($G?(&6@BB@*(71+9&:DD%>%@F6@E$5#$<;<=F%*);B0=2@9
@r2410
CAGAATGAATATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACG
+
8AG>7>4)$9;B%7H:/D'?+C<A/!6//,,?4>.23%-*BA@4!-E$6E%6C=C48(@":9+E&E1<D4/&-*!31'25369(/=#3C-?0>!CE*/&E
@r2411
GGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTA
+
;'.!AA,:FB:F?A2.:GC#3>A**'"A,E8?2%&(&)%$2*!F*<,G>">;;=B&01>!97;<7/'?@-70H
@r2412
GCATTTTTCACCATGCTCATCAAAGACAGTAAGATNAAACATTGTAACAAAGGAATAGTCATTCCAANCATCTGCTCGTAGGAATGCCTTATCTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAANATATAGTAACCCTTAATT
+
4A:++9*2$:&9%0B"3E")).H0(C</%/(A+"#H()1D:=HHDDC?*7BEE-:)'"+8=)@GC+?)!06+',-,*7$,@E/?4>C:"(E,&)9@2:E.G!6.B661)7;,A<20+6>;$>$;71=3E,@5:0:C5H;G!/%%/%H'@G>.C>;F,34!B(D
@r2413
ATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGG
+
*>.?(4";G%05=!@8;)%H*3$HA131;"H;?C6&*.6+-,?G37H%6,0(3,
@r2414
NTATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAANAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAAT
+
'&6,.<58@G21=%$@?6&,@A@AHC',=:&"1<=#@?6F)./.72#0/,F3!6"044=05D&HF7')#G,))?FH69:HE.=*<)E1$'5D!15>+@.))-)%@%H<0"$:3D?@F<%/=C"6$=G
@r2415
ANAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACC
+
#$<CF<%@A%HF(52<#/66=8>F8/D&?B=.@(G0=A.>$67"4$H9F#/@<'A,82+<65*
@r2416
TGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAG
+
.@:;+<!2;(H4/,8)7(!,1C<B:?>.&$/4ABHB;/FE7A2)60(5!="D7&=C;2HGF3BD,0F$A0A#E5'?7*%#'!$2DD&E'1=#C<.E9,++-$8C)24G0-7@16!,57/-0</6H@?2>+=B.H6?4H<GGF61?/9").DG"/G@
@r2417
ATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTG
+
&D*D,;HB-'D@;,+9)/B-4;!&)1--/./@#9;5E*:-:7-7.1->::)>C'/1*91>HFH4!330'G@*%8
@r2418
CTTAGCTTAAANCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAGAGACGAAAA
+
,8)??%+4<#18F!)B),&F:449+8*=)).7%*923D;BHE4B?F"+B$&A?)$E'D;#?E%<CF$G>4/!*&)7322.83*0)'@8<'H
@r2419
TTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTCATAGAA
+
=%-$;!#@&G$<1,?""?F:'>4G2)#=A8,9:1+7G%F;5A1D*:%FG0$0/B;?,D!B3=.B;.#
@r2420
TTATCNNTGTTGTGCAGATCCGGTTTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTNTAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTAT
+
'$&)&&*+%&+("!%$))+$'*%'!&!"$+&('%**&#$*')$!(()*!$'(*+'"!""%+&*&!''(%#'!%*#%*%)"'*!%)'*')+*("+&!'*&$"*"$')'%$'*(((
@r2421
TTNGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGANCCGCGAANGAATCAGCA
+
;A+CH$(9E=5!%G?%8(+:259D)%9B+(A,0"1?-";''C622>-E3",C7$<E2D@(?<G"%,9F$*
@r2422
TTCACGGTAATGGTCATACCACTGACCGACACGGTGGCTTTTGT
+
>"$=<%60$'+A+06")=+8/8@:&:*;7>,A,&<)@-3D&/5G
@r2423
TTTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAA
+
?A"@)D)&*744G(*>F*(.70B#2<H6C,7"E/'06&E(5H!-0,+("HAACD0%>6"::
@r2424
CGTGGGCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACNCT
+
E?*$A%D8H8A8)(;)./4,"D!GD'3.>2G95(0<$=D;,)A>."*F4E-3=83EH4*H
@r2425
CGAATNCTGNGTACGTCNNCNNGTGCTATCTGCGCCCATATCATCNAGTGGTCGTAGCAGTCGTTGATGTTTTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCG
+
''%'%(%"&#"*"'%'&*$)"&*&))+%(!#"(+&"!!()**!')+!"$+)!++%&&$*%%)#$**'!"$$'&)'%%!''"!(*#('!$''%$')!*%##)")***)$&($)+'$&!++)(##*#"")!($+$#%(#(+'%#$$'!&!#)#$+"#(&(*!)#()*%#(#()))""+'##&'&+%&%$)+")$&
@r2426
TCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTANACGAAATCGAATCCAA
+
,@A:2-8D-A/1.B+F"1-A'2!*3=;*C*2(,;F,&2G//(*D$2@@!=1@
@r2427
CCCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACANAAAAGCCCA
+
+'")*"#$"$"##("%&&'))%#*"+"#+%)!'#')!'+$''*#)+&&"%)!!%#)$%*'&
@r2428
GTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTTGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGC
+
=G6H565H!C7%=@+FB9(&9<5,C5=%>.89-AC=@)'?@-$;C->'??G=E;6&-A?@:>-"=H!.1@-%:$"1,H4)41/5&=A)>E!B%/H2@.;3%+B"%:%;:HG#"C;)8FB18(.,9)<&,#1>.4)'7+*D&<0DF8=!=??)5;A+.5@&2HB($$/#@?(CD&:DA<0$D,=<G)5'B!70B.$#%F&6(+1F;#9*H,H.#<9$5:%&7<!58EE0="D.G"D;39"<D55:$'4E>:6"(C',:@/%(%
@r2429
CGNCGGNCNGNATCACTNAGCCCNTGCAGACNACNGAGGTGGCTNTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCNTCCGGCGTGNTTACCACGAAGCC
+
(&*(%&"*%*#(#$'%'"')"%$#%&*(#%(""($)$+(("#*!&($#*!)&'+!%!)*&()+%(%())*(&!'$))()!!*((''%)"%#$)+$%(*')(!))"%!))#*'"*%+*%%"$+++%$&&%'$'$+"%+)#%$+''*$((")!#)!#(")!*%+#+')**!'#"(+'++)"!("*&
@r2430
CGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCA
+
.FA-4=G#/0$&?7;;*2H6>*<%0.0F(;&*B$+>1*"@
@r2431
TNNGCACNNGACNACTTCTGTTGAGTTAANAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCANACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAAT
+
'!!'$&'%!!!*!!)%%'#+)#&()"#+&((&!!!))))$'$*))&+!&$*#$"&+&$!'(%#&'#'%'*+!')#"$!$#!+*$#(*(*"))&)%&(*')&'((++%')*+&!$$)('*$$)')"%*)(**"&')&+*&&*$!&$#&!"*
@r2432
GGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGT
+
G1(+G<3$BBGGD3H0%47?CE45!6<C%</<616*04*4$?"-D:%!06//FE2$%G;EC6#%@-H8#%5CC:>-<DG-6':;.!6?52&2D./E4H@6=#CDG@><<)-'B*%,@F87$3B0B'6*G6'(@7H&3.;62D5&B/&9#DFA'5E/3!*'.@H?%,?,=-(4F
@r2433
TATNTGCAAATCGAATGGTNGTTGCTTCCACCATGCGAGGATATCTTCCTTCTNAAAGTCTGACAGTTCAGCAAGATATCTGATTCCANGCTTTGGCTTTAGCCGCTTCGGTTNATCAGCTC
+
6!5,223#*'(#>$:2A/;?*74H(=E</>=9)$D=:F2+.;&B/':?E3G*H#5B23H",+-".3#A6=08'./>%B37:<>?);58A:-8+4'EH'3<%D366+-:B)=0?/;F?+:C:#
@r2434
CTTNCNATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTT
+
%*)&+$")#*)$)*!')(+)&&'*+$&+*"*#$&'!$'!$&"&('$("$*$!&!')')$&!+$"'$%($
@r2435
ACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCGAGGAATTGGTTAGCAAGTTACTACAGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTA
+
3'5DB"C@C10)3='H44523H)H:7$E,9G%G3&,60H)#$F.=&1?B;EFA"'/=/E(998"A(<1>&"#1)F$=?2;:F#$"6%F'F<.%/'10%4/%?5!0G6A)(=3=6!.@<,#*?8B$2H=9>9>6./9HF1.;4<2*=',3-58$:/$)5@
@r2436
AANACCTCCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAG
+
)"!(#$#**$++$#('*%*$&+$$#"'+)!+%("!+'+()!#$)'$(!&#)!"&('$!"*+))*
@r2437
GGTGGGCTTTTTTGTGGGGTGAATATGGNAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACA
+
*G/@!G?!'ACG;64%6C+B=CAFH75E54A8F/CG.63(A8>A$"-/'%83AC;=C&/G"?@
@r2438
CAGAATGCGGCGGGCCGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGNCTGTTTTCTGCCGCAACCGCTGCGGTG
+
3=&/3D:,%"/*1G,@;0#B/?F,&!E%*D7%BD#C*A&!/>0F<;$,.&"?E2=E/BG;%9.A**?)&H$%3,4.'&>!9B?3&;52+7660D."AEH867>04.G9@=6*82.-#D*970EA5=1;:<?)A&F,
@r2439
ACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAG
+
;BA"0):1$F>A&,,$1(BC5?#F*8>=9%6G%!#F<,+,20
@r2440
ANNNACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGCTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAAT
+
("!$+*"#(*%&"*()%'")!'**"&$%($)*%'%&+(&*(%##'$%!#&%(&'(+)"'$!'(+('+$%$%&"(%$!%%!$(+$*)!)!%#+)!%$!$&(+*'
@r2441
TCCAAACATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATNTTTTAGCTCGTACCATGTC
+
'4(@G<*%=GH3&/E$<5:D%#:F.)793$:D*EF,18?(%$F534:A1'%>%%8G&3DC(*D
@r2442
CCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTG
+
'?*,D")'7(A%&*7<=)><C,E+7?/?H#B?<("%;?7#=1D%8H.-'4@"(.$'H6)>#8"?*;AH8,=9+E33??747%A97(C6(;&E50D?:?"';D"#4H)&E//0C>;>*(A!B$9"3>,$()>:74&/*":>H<-.*;B<1+%*$$;!?CC>/:65EE/FEE4E:B(A+04C9A>8
@r2443
CGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTACGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAAC
+
G5FG=$3''1,@A8.D*5@C#3-7.0C@6,A(<,?./30<+8;;:=&E!7>FG>3>=-'-3F?#$D<8(B1B*'H*77BFD,=.'B;0?9F30B3"B55-&H%2H2FD2.A566C)9196#;/"/G(83G=5D:1
@r2444
CGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTA
+
C8!#6B+*,"<@,7B9'2)D,&>45@@C3%4=4@A>&71#=8
@r2445
GTATTNCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGAT
+
@!E7?=!?41$/><>CB./#36/E)0'8%@&%*>=A>,D+>.GC3%98E'/#,#1-)9*
@r2446
ATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATNAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATC
+
(++**+!%!$#)$)+)$&%)&&('&()'!+%(+'!'&++!(""$!")+'%"&'"&*+)%$#!)("+'"%%)+&$&++!%(('!"&#*)$%$*&%#%$)!)
@r2447
ACTTTGANGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAAGCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTAC
+
!2"3$EH;0+8+D7-%<;8&C.>C;3"6G%''-0=HHE+*:7.?D&!)474-#:7C?7F;D2::(HEH(5&#E*::/::F6919C#@164(GH@,A=6-=F:ED/CE1@,H4+095%,14E<4@$9%G869?&#&A;CD")=@943(FC'%-#-#CHE=-;HA<97D:#+FA2F'E(2<6559?!-6%!6D#>E/E!/4$=:%9F#/0=BD#29:D%@5E/%=05H5B3!E,'.B?@.2(';"BD+#(5?'(<;&13$:;C3:.+<-+)C;C3D"-=2;G=.?$;#H*$E9!F>-&&902$7960>1=H:>,!3"<?'6%(?%0B>A':(
@r2448
TAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCNTGCCTGGTGTTTACANAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACGTTCCTG
+
C?>5,G?3:.-7708C7(&-5E$$"*4=.?"!,?$4/E!H9.<=CA5+%$:395?F6?36(CDG=417;>?@AG>D')DD7/?1AHD>-H(0"<FH!"(F#78,>+?8<"=0B6$:!F63H?$A/.C<B*"3:)<?GC=D
@r2449
TCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAAC
+
3(CD58D!F8,!--F1,"?HD+'G"1-H?7B+;2&@AC/2$F+*440,;.GBGE
@r2450
CGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGNCTCGCCGGCAATAC
+
+B%"A96C.9+/%C1F,D>93<()<8#8&;D1,)E9:6)B&8.$94HH$B#(*#FB2%
@r2451
TGAAATCTTTACTGCCATATTCACCCCACCAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGT
+
(3;8@1.?8*56"B;@=+6B+F!H-/2&+!0%63<D.$1.-G7;+6E;F83#2=46@$5C*&=G8*6$>'H
@r2452
AGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTT
+
8)@AF+@-E8=DB,B!E*C%E;?)?;'!GD7*8B'+!:8!G4*H@!4FG/(E*%
@r2453
NAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGA
+
&2%2F(/>#"&>F):+;F$#5=E7$7;B8B:&%@#<34H:%'$57C<2.@H
@r2454
ANCCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCCGCCAGGTG
+
)'+$&!!+"$"!')$))#*%&*$!+"(%(""&(!#+%$!(($)%)*'"!)!"$&$"!*#%"%%'+"*+!++'('"!))&*&(!&$&&'+%&'$+
@r2455
NAACAGCCACAAAGCCANCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCACGCAGACCGGTATGAGGCGGAATGTATGCGTCACCTTCACCA
+
#2+*F6307:5%:8/?4$&8-.$1GF,!76A4&((ADE)A=?8H>?:49F-BB(8?7BG&;A6=%GED!<953(."<C5?%1/:#=29#*7,=*AF7D
@r2456
GCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACG
+
D8G:F?E1F;&;G,5#$?&'D4*A&?-"0:?+901!+,#33!-#H1B>*A:H
@r2457
TACAGCAAATCCTTCCANACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTA
+
=E1$>9''?H<42,.7D3'>&G=-&D3B$6'293/70@D)01HC'?0>52!'@>?AD(-&=D73$%&,
@r2458
TTTAAAGAAGTATTCGTTCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTC
+
7'8)D&-@"HC+81H8$!)7A!B<5*D$BAAHD2H>,?$"!(-#7H;G1*</87*%G5@D,DG..7C<$:=+7G3#?=;F721)6;B4)1F/.-?8!&1@/+*%9?@";@C98;##E(-;%A5.@9+)@D$@"1DFC'>3#1@C2.1F=-H657HD2?3!)EE2EB=@$H6;0@H)D))6>$(8*5),!8./9F&ED>#1&DB&51%-?;0,
@r2459
AAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGC
+
A6D#!FC5+/B%3B=G@7E&)#<#G9%"7,.8=CFD%4'C<!$):@#
@r2460
TTTTAAAGAAGTATTCGATCAAGTGCGAAAAGATTTAGAATG
+
74(5*>637"2=D>402=G8&A0'&HB66F!$.>HCA$($*$
@r2461
TGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGA
+
>-!@:>2?3>C5<!%C%#62@@HGA*+4B65?>!)H5%*-G;6"?@D2>=07C-"+5>*"@B$,#-"@:$>4>*B6(04:G!48F*@-9F2D8B6@@('82D<"CBBD=6.:75/.*30$<E.9=13G'/%)8;%<
@r2462
CCGTTTNAAAAGCGATGATAATGAACAGANATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTNATAAATGCTCGGAAGGTATGA
+
5E/7,--G3F)/-8?;#1*--C,*:/='9<.(B%;1&&#B><-;(303'?E;76%5#.5FE*&5B=@D>5H%39,:,,%$-&>?79,70/6'='#4+%A%>=,3,.>D$;/(*
@r2463
GGATTGGCNTGGGTTTATTTCTGGTTCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCAAACGTCCTCCTTTTCCTGCGGTAGTGGNAACACCCCTGTTGCTGTTCTTTCACAC
+
1;,A;!&44#F47-G+8C&"6<11?8@!'@5#&!"<9>H*>@7+'6/)2CB(B5'3+$GG4*8/DF(/-A.,78(17&/&*D%)F3025,1#05BE<@)B,#%>,H6!E3+$9$4F-H60=E>*C1"@G!<8=#,+E6!14A3?.310
@r2464
ACANNNCTNAGNCCANANTANCCNNNTCAGNGTCNTAAAGTNCNANNTGNGCCNACAAGANNNNCACNNNAGNTTTNTNNTCNACCCGANANGNCNGNNCCCN
+
"!!#!#!""!$"!#$#$#!#$$"$!$#"#!#!"$!$$#!#$##!$"""#!#$#""$$#"#!!"!$#"!!##"""##!$"!$!#$#"$"$!$!$$"!##!"##!
@r2465
CTGGCCTTCGGATTTGCTGGTATCTATGACAAGGNTGAAGCCGAGCGCA
+
E8F5-0-*6''/H2)"0=+F+,=&-4(A%B1B+/8-<1>=5/+#?%$??
@r2466
GACGGAAATCACTCCCGGGTATANGAAAGAGACGACCACTGCCAGGGACGNAAGTGCAATGCGGCATACCTCAGTGNCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTCGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGT
+
G>%@<GB8H!7H!D:%6%<<10'*6<D7@)?"*&5F07!CB*94E")H5;-$-"%+H')!B?D8F!$@G@C6*3"1B&)B@%259!%#%&;9<4</D5A.2G'--1504;074E.'32>)?314=:,<A:@,10CG<G")@$B/<0E,92$"34G61&H0/+=9E/6#>!5:!%-586/!EC3G>*2<+)
@r2467
CACNGCTGAGCTGCACTATCCCCTTTCTCTTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCAC
+
+&-*E?/9!C2/;0>7?4#2(9'%6BC%16/)48/,0410!D<+,65CB6*?H9(@8.A8,"?HHA7;?=(CB?/@'G
@r2468
TTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCG
+
;,A?9BC>-:G-'$6,4961$))#03/8?'&:97H:/55,F<B"DC1*/67*&"1$0*6#>=*;%A)-&-:(;C#2%:5D!G)*49=-@H3FH5>"00/'F.=H:,48GH=8-00/$9#D<@C+F9BC(!2
@r2469
ANGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTA
+
%.BA:,%(<*)H)3,8DB9++CA4E0-8,0?<</4D<7%?@4;<'E>0:F:(-"EF>.181!?1&/7;%#H)=;1;AED#):?>@=06&%AH%!403>G:.+21;,"
@r2470
CNCTTNCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTNTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATC
+
*!#"$$+"$)%$!%(''"+&#('(&**#%'#'+!(!'$(%*'"$"$&%&&#()&!)!*('&#+!'+)*#'$!())%$!(!&$&")$%*(&)""++&*+(("($**+)"&$%'"#(##)+*()#!"*&%&+!($%*("+$'%($%("*%$)*!**#*!#!+"#!!%)&!!&%+%($#+#)&"+$%**%)*%%""
@r2471
CAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGA
+
$C$?.,)A(?1;0=:*F#+9H'6+=1G5"6:=&D9>GF7A$?1C"242.5C8C0C(7)@6>)@2@%=E+1*<5&<H8;#&670E@:C##>-5%*C05%"GH>8H450-.@/'!':8"0"EG,=9&#
@r2472
AGCTTGGCTGTNTAGTCAACTAACTCTTCTGTCGAAGCGATATTTTTAGGCTTATCTACCAGTT
+
/F/(=1D0/(0-1%'AED%E(&,AF2+C6#?'+B-<B9;A@/=-92!8?B/'&*#<%G8+0')?
@r2473
CGGTGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGA
+
5B-:GG88;:"9#6@#>8??1F!0"#GE)A*@D5AA:B##?-=:G57*3085#*
@r2474
ACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCNAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTACAGAGAGGGCAAGTACCGTTTCNACCGTACNCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGANTCTATATCTATACCTTCATCTAC
+
@$=F420&;6<.#95(G0@2;'.@633-,G'0G@2G*6?G"@=,+&59.&)2)"A>!,2*6$<71=.*(D*8+0-4>>$@F@?&9-@=?;H".1E=2;@D@?/,G;2)=141!,4$@4"&04F0=,D#DA2+3;=%2('?$:,-;B7,2.G?061B!85?;&"=GD;%2.?1,&+8@"33;5E$"(&!="'(&DG&>@<;"B+5+%>>H*C7%,+$-%B57DB/D7DA92)*A(?@H)EH'?-3.?5
@r2475
GGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGA
+
&GBAE,G:(-!A6%9D(!/,9D9@;800>,8*@5>=?-6.74$:6:5.?<"/$C5=9(5"6HC/$?C+'D*B/3
@r2476
ACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAG
+
>.30)==66)DGC=E<+>?>)BF!/.@2B!@A%7&9#@3,54%1"$7A-'8
@r2477
ACCGNCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTGGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTNCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATG
+
G.(0HEH,-+8.?!'/;F=F5?)*"-"()3C$%"(>76,;75((?2H!!@&/0BA=%0>/C@F").-HH3&G93=AH49*1C!><3C#,1G(F(C(545*(*$8%D.1857'8#$H3"C!5'&4G()6,4E$+"-&D-16B(E=#2C@8D44A:*6./,78*85:E,C!A)2"55!"/9C!G:?:B@6?"!31*G!+-A4F==-=F;#=5.9H"9EE.3-&-9G#<9:&?G8*,@),"C*D07*)$G393%D-"5#3BD3(90/03/<C,#($0H)&50%D.((
@r2478
TTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTNGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGC
+
3G9&40<G?H7?9/*7@+0=>.:5*&*%>38<41>F6.-7C0D;'B4:37A5199F&)03//>5;7??+E:-%F(A&1(?%A>8%!(C)?>"92E58=9AE6H'=2A,'8!,6"-,27%-%=$'%-.$;;,)(*@&&+7/D!&H@3=%"@4GF&63B,<68-<:+,=B8.,7A3+:F7D"@*0B&==+7&+87.G(#?70=$24"
@r2479
GGGACGATTCNTAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGAT
+
H0=5)4'.CD+-G@.B@D7$*6E1%;$,-1C%4#-/=4D%@<27"F"?'H96#>=:(:,@@7!"E!,1*>(-2>9.FFA#+),G>07/:<6!1$,1%61A/9@H,9+.%!$5.!(!
@r2480
GCTGTCATTAGTCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATGGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCNGGAACTGTGT
+
3/BF7#4"=)-;3,"GFB.@')E&<G0?,=-6(<H4B55EH#==&@9?9BE5-649"#E::#.77A3DG+5'4C95473BC<D@.1.*';<G@%AG
@r2481
AGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATTATTANTACTTTTATATNCGCAGTGAGAACACCGTTGGCAANTCGGCATTCGTGAAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACNGAATCCCATCTCGGCAAGGAGCTGCTGGAAACAGTCGAGCTGACGGAGGATAACGCCAGCAGACTNGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGANGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACNCCGATGTTTGTGGCGCAGGGC
+
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
@r2482
ATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCACCCAAATAAAAAGGCCTGCGATTCCCAGCAGGCCTG
+
@5FE569H;/:3%;-BEAH+:/6B!D9'<6,2/-'C9G$/D?CA;@0%?4E=;!4$0-CHHC$<-D"<!')#
@r2483
GACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATATGCTGACCC
+
'?,0.!7<50(;)E#?9968DG4)2G>)<$4D@&@6#$)D?H#?*?D8$3.8$205(&HC,H*C
@r2484
GANCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCNTCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCG
+
@<B/5G38,=6D$+3230),95@53+%0@1;H>C?!@AC/<0H5&%-G;"##-4;/'$?&&B&4'CC,-!":F995/;9669B:).G&2"*C%@:G37/:?/,
@r2485
NAGCGGACATGACGGAGGATGACGTAATGCTGATGACACTATCAGAA
+
"%&+$"($!($*%(&%')$*!#)+!%+$%*""'$$"+#*("(("(#*
@r2486
TNTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCG
+
$%.&$D#C3%/!<>+"-A:A'3C)&4.H$,$1H!G2A#A(A.3AEG%;+A4'2$)7$24;
@r2487
NTCTCAGGAACAGNATGGAATTAAGTCGCACACCCACAGTTCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTNGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCNAATCGACGAATAACACGGGGGCTNATGCTCATAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTNGTTTAAGGATGAACAGTTCTGGCT
+
$504!<4$682>"!1@*,"!!&)%0#)+F((%F@7H*7C(-2A!"/37292#C50E$24<9#A#==2>D55,<E9A3#-;C;@1<&(*.?+0>!<0>&,@@?D0G$")-+(&A:A7,DD)&<0$B*8=.FD$)%)46A483$CD,(=AA+:.=(;F&EC)GF,!4&31!%G>"/3E!B5=+D:&:<)G555'$+G<)'2;*$4F'5+4@$*8"(G.;=+E>*,"/')H3>E?683:
@r2488
CATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTCCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCG
+
=/-<E*GG.?</)?<,?5@E;<%HA!>=)*19D#&=?>&B;"/(/29E;6-A8"8&8?:70-DD.C8G60'%,;5@(-%E2+B:DH!5+-/'6!.#(?<??),D%G9"C2#365*B15$4'6?2G16.'..:97&-#DHAD043;A=/!
@r2489
ATTATTATCTTCAGGAGAATAATGGAAGTTCTATAACTCAATTGTTCATAGTGTTTACATCACCGCCNATTGCTTTTAAGACT
+
F,(1+/275>9!>"-:%D#!&37F&++-)F5+H$+/1-D6D/1F5/1D(A+2@,HA-!:,65=H79D(59G/A)D)!@#.#E)
@r2490
AAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCNACCATCTGCTCGTAGGAATGCCGTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCANCATATAGTAACCCTTAATTTTATNAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTNACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTANT
+
?:9;1077<0=7C@B$4F5%8,4</$D0?+?&>CB(9FG8!)D/%(&-?<?+'GE<+40%-&*F:<6BA44*D#:1#@9$-C;7HG40?$6>,'26=@(.5+?C;8$+4>/4!A>:4+6297&G-(/$+;'*&)(G%?$CG0*!66CF=)%:-;'7H9%4G22'C3=?/C7-2&90GFB.?;>104$87D;F(:26F3%31=CC*153F<9?C50AB14B,?E1H+8;5'3+'%"9C?0=A"&#1.=E'4E1D>"-0?='HH/&G7(;("0G#;:#1+):30"E;9!#+/+DAF)#F&7><2&*A%D;!E?'#
@r2491
GATCAGCAGAGTGTTAATGTCCTGCATGGTTTCATCGTNAACCGGAG
+
$51,#5551%($>1/.D51)?;8>-0(B(F"$6*>$:8,!./$?!$=
@r2492
ATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCGAAGGGCCGANTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGNTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGG
+
(2&)$DF532!&/*%5=?;(!#98%:'H8/D1*<A%/.%?$54*&(27@.E)B4?H&>/#36>>70E?.4F;866G*;1=@DD/,).47BGE4?F"H:%3A8<-*3?(57?F)C,F*60DG3A4C6!C0C<3"45"72%2-C-AH.7GF=#FA/5D1%B20'4);5<3&@H&8$5,G0A@!!ACF'-.9:0F0E.43!1#%0<29&!"#$C'033*C/C;,CE!2%/3!+DH.DB0-E&&7)>$:/A
@r2493
ATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAAAGGCACGGTCGATGTGTTCCGTNGCTGGGTCAGCAGTATCGGTAAGGCGGTNACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACA
+
<.!!8@;;-F#)?@0G8'30!B1%01(.,D!A!17&B+$A$F6/9H!A-&&,D:)0/!D%)'44(4)2B*:AHGB0=HE.)"2-3B>%&;"A/$)8G,3#2E8&1;'",AA?0CA9<@0=/5<&#-71>7(A:.E)5#>7@.6G1!!,5-<<DH/&,$&"983E"#(+2/&H+"0>
@r2494
TCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTATTCTGNTCTGACA
+
5?,5.B4<!G%>7$;@>#*+;G63/88>2$*.>=..G+861-%(-A#F)2(:*A!!F(4/,84A>$,,+/3B@(D,*-!@9CG.$D8D?8*-*
@r2495
TATGTTAATGAGAGAATCGGTATTCCTCATGTGTGNCATGTTTTCGTCTTTGCTCTTG
+
6@70B%*F89:23'$A(E+?(.G6520C0#E38,!GA),BC/>0&=F1.-*.G*#%0)
@r2496
CAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGA
+
$07B9.7G@3>A+;8C@:D&+#==!D;-14C>B07A?A,77)>:$1.57?&C
@r2497
GCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAANT
+
@:D01"#<?!<.B7-*!?72F72--+&(9.,1A))=!4)C"9)3C9%0?+<'2FGB7'&
@r2498
TNTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCA
+
*"+('&#%+&*(*!%#$''#+"'+!+%%$$&+"*$!(!##('"""")%$*"'+
@r2499
ATGNAGGATNATACCNNTCNCNNCANNNANCNTTNTTNCTACGTCTTNGCNCTGGTTTAGCCATCATCTTCTTCCTCGTG
+
&*(#*')!%*)!*$"&")&&&!$&*")"&'&#&#!&&%'$!(+'%"+!&*'')%'!"!$&#$%(&+($$+'#(%!#(')(
@r2500
TTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACNAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAAC
+
+7,5H%/-G"<0:83B4F6976.:'GA()$+2).(!(-#F085?**4A$/:@4E:H(:?30G"9A6BGC*3G&45'#CB#D!=/=9=CC@9G=$A=)#7&0
@r2501
TTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCATCCAAACCGCAAGAAC
+
$9H?7$!"-/@'')7*+)?+5++,*%>BA>%0?G+%<H1:=??*,7,#2F&.&9."C,4#6",%>C+G#!E0)G'9<D:C0,#
@r2502
ATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAG
+
3D>9&B::!5$+58$"$D;8B(4.C*@>53+A9B$??(%&A"F!1+8!$,
@r2503
GGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTNAGCCAGCTGCTTTTT
+
7$=6.'-:*&-$/@*2(=5,G3%;6EF!*:2E6,-*5$0*H16=*B*<#B<14:,&<GG9=G,*1;$<>,;
@r2504
AAGCTGCGTGGCCACGTCGTTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGTCGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGA
+
C6#E5->*@!8"8#E/</#!GAF.8<:69%%=(9;B.<HD$=7B!$E=!<>2"<0E!B9*-6G"00=5FH6G5CBF(#-%;!B<'+5.,@E"C:(.0278G'%;"0$!6/,$-!F;*:;$<1
@r2505
TCAGGTGACGCGTCGATAACATCTGCAATCGCGNCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGNTTGGTGCTGTTGGCGTTCCGGT
+
,E,!3<:-1;$F+4%6<;+A&*C(DEH7(4<'/D&"3B6'G19H/E!-C%.$%H(0,*!/7;CE/6?D&%7<?A3%(H<#F.&2>8@1)G-3,$%G>H,B,3HF)0*(7C
@r2506
GCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCNCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGNGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACNATTTGCTGAACACACCAGTGTAAGGGAT
+
)$%(+&+%#'+($$(&+&"+'")'$$'!#$$$&"&!$+'"&(*#*"$+$#&"+!)!(%%$$#!&(&"!+!#"(#&!'!%&)'"#+$#!%"$!''!'$'!*$$&#"*(%*&%%#'$+')*&+*(&!+($#(+'"*'#$+&&(%*#+*&*+$+%)("*#"&$&*#!*%")+(#%')'$%'')%&*%*'$"%#")$)$(&!#&"'$$')$&
@r2507
CTGCGNGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATG
+
&4+!&B?*0%4A.-HG=%%3>43E,/##.2.38DA(F#*8/,@:)*-/<$)A4<5B>-"<%A6B?*"-*1610%#8C)@
@r2508
CCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGNCACATTACTGAGAGTCCNGGAGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCACGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACT
+
-(.7+D()D,$!91B&F$;G7=.F)H9,5?><>G=6"HE35.!>2.DB70A&"2*3"H16=F&"5EG8B),*6;<0G-'6A"/+&#<8F<&CE1?8C7!1&'8E9E.2217"-5(EB(?HBB@)G=;007($HDG;A4'G8!"-?>@<8B.5B86<2:%'3+%:715&(1<@B:FAB=*E&+:2<E-:<G1$3G&&67/>0?F&#GA2;&*A+AE:/56.9557B3=>.)(8(D9<=6;1A4H&FB"6D"E%&'(>H1+2'ADFD&GD=;/9F'"217/"+?//9&C+C?G>)GA*C%6C8H
@r2509
NGCGTGAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATC
+
%=)-!-3B+08G%);)>*"?G$>;('83(9()"F-BD-4'%??$DB6;/"8$HE>4+02CB.62B8A:$"23!,<
@r2510
ACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCA
+
H0D&60$B11)'42F=<1%>;6GG@>A9:070/%?'+<70'F.567!C6-6%H320+F-D:3A#3=
@r2511
GAAGGAACGGAACAGCGCCCAGNCTTTCGGATCGAACACGATGATACTCACCACACCGCTGGCGTTCAGCGCGTAG
+
D:66@$-H">3F2*3",/G2FE'9-))#BB%1%4CAE)"?%($;7%76(@1)245&=)G7$%=GH>?41)&,;CH2
@r2512
GGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGTAGCTATCAAAAAACTAAGTAGTGATGA
+
?"1;(HB=&(B8D2(1)*-$>F=F<0@#)6F1&D$)"!<73=B(821C'9<=)B&B5/*EGBB->%#4'3C@$+B>"4.(<?36423?"$:"#)'>>F:'0.)"
@r2513
TNATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTAACTTTCATCACGGGCACCCTTGCGGGCCATGTCATACA
+
''AA71D(/D4G2$A*(,!?F+:#A@DF%?7"-E/=D6-/;78G:H?E:$=(8%(+E($#7/=1#$!3<)=G)?:D!1.69B9$!1
@r2514
GGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGNCGCAGGTATCGTATTAATTGATCTGCATCAACTTANCGTAAAAACAACTTCAGACA
+
8;,$<!A3G0(=+8D&/2BE71:@<1D("4/8$;(1<*$'$8;38'?=4H(#4./"831$@H1!:")EF>/A58,A=#$(1@4'37920E@F%:F*G@*8;@,$>=E>@E7H**<4CB?<<H"H0#F=E3<;&3#*>?$CG-:"2C#$G2$C//91'9(&;"0E
@r2515
GGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACA
+
%%+&%"(#!%+$"%'!*)#$%*!$"*&$$!$%#')&**!)$$$$)(+'&
@r2516
AACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTG
+
=7CF=GG==:%)E%@?CC3$"16?>1H$7:.6%G%<70"><A72($D@=.%=/(2@@G)-/G6-"1!;#7HBGF=E'4&)%##FFBBH4>1$/B(?-GH-&50*0!>,$*
@r2517
AGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACNTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCA
+
EF6/"*@9&30@<;9.)A782'9<)7"@:9.A8/8E8H>"C%B7.107"D''07#H(*"(+&%)(1&>)'29"1*<*G6448+8H;;DEHFH85&7;#%.=-)G,=6AC096*;:3?%/A/;)B71-*4F<-!F!57<C28/10&7'F6/>G8**G%A"?<07D93(,52HG8D*!'B0GD6&361!
@r2518
CNTCCANGCNTAANTNCNNNANNTNCNCATNGANGNCNCNNTNNNNNCNCCNNNANNTTNACANNCGNNNCNNNNANNNCTTTNNNNNNGGGTNNNNNANAGNTGNCACAANNNCNTNNNNNNGGNNN
+
$$$!$$!$"!$#$#$#$$!!#!!$$#"$#"$!"$#!!"#!"#$!!!#!##$"!#"!!"#"!!$#!!$#""!#$"!"$!!$$"#"!#"##$#!!"$##"$!"!"!!#$"!"""$""#"#"$#$!!#!!$
@r2519
TCCNAAACCTTACCCAACCCNCCTGTTCACGCACTGTTAAGCCGC
+
*&%$(+(+"$%$&%'*+#&))'!*$$(")('$!"%+$'&%)*($!
@r2520
CGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGNTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCT
+
7+C);7/4E##=55*'!10>8/'9>$5!%->1H6+B#%>G/AD,D#/063/91C%'=+505:7?<A@-,45;),%-GAEC?";$'%$+9464%#12&&12%>D5!<0!E1+3"819"),6@*;/&"E.)@2&B*04@C/B@.F1'$'C),999B;%5.412,96.8>E2'70>AC%+"5*./8;A/0G9@*8):E#81)34:C5,85BF'':C(A+)**,A-$9)83G/1$E@'0@2%=/;$>E>:=G"HGBC6D*@B!D9/&?9EG*#F5164G2B3@'4</$<@96/*-8;0./<D>:
@r2521
ATGGTATNGGTGCGCACCAGCATCCGGTTGTTATCGGGGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGANTGAACAACCACGCACCATATAAATTTATAATCTNCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCG
+
#;*)4#->838:/-E11F:92!4".<7"G,7.@E&83?*+:-2%@?0!-)5"&3*':!33E)6(D(>2.=,>$@;>%2??92%=&B(EF25=@(-B.C-;57=D0)H6D(F<5>:;C!F86$2CF*FGE%-;3A9B)%>-';2(<&FHF;-+@;??(0#-D*D,,B(;(<>8#,(:3.44#*C?$$H?=3E@097#."A6$B9G3?9#)+&7(*$.<9>G>EG?,+F*7,*4C'"24:/$F342.#".>-@6<?6D
@r2522
TCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTG
+
E&G6ED,65#&&%/8)2*'*F/;%(C7EB3E,35#G/758(>#>4"4C;'A).DB;';'>,-9D3E1<A&?A+&1<,C4+6%"0+*=#%;(>?+..E9#!F*5H1?4062>(A0*C@G"E1(-')(&0@32C;;>1B8)/0!8?)/BHE5G??@&?GD3D
@r2523
ACATGCCTTAGCTATAATCTATGGCAGAATNTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATT
+
B7D2#',6$3BG*D,$7C)FE0#4#/C@)1D9+G$#?2>@68@C2!4<5(F?#FG5$DC%0ED2E?!A.9"<18,?6C6:*?8#5D@-3</+6,#?.0<-E1+.G!>.:)7=D3,%,
@r2524
GTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTA
+
:H>G!+G3945+2<6.-;1C69)?E3A/D=0,H2@6/4>"8<A$6+!>7!?!>"%652A09A%CA2C,B$@<>AD7.%:F&5C3(GA8!1@+<61%9G/%66+?*1&*"=<'D!'3E-A2<
@r2525
AGCTCGACTGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTANCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCG
+
>6,AA1H).70A?G">9,>6B&'A,ED4(-#/C";?3)44D-(.=&*&C,!'5"(,::.$123/+DB;.>'$,B>057!..9)&=EHB&)G9(H-<9D917?-9$)**'$";8!:4C$AB@;-=GF.E*(,HC/E4,)4=*$$3EC-GA>5?30>9
@r2526
GCCAGAATCAAAGTTAACCGNGGGGATTNGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGC
+
G34..2EG>337!E@5>''5<05E!++2!1,#*/D7&&.@%G0$:9=74H"(#3?>=HA2G.)*C(/2=)
@r2527
GTTACTAAGATGGATGCCTNCGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCCGCGTCGGCGCAAAAGGGCTNCGCCATGT
+
"&*(5"EA&B7%+86BE%AA,"24#()(B$8GB,=3HGF:!$;%;'1A9D!$/AG9:(1.*H9/;9F73%:FC1>>AF&!E588-:,6HDHA6.@C6.A<98<#)-0"0,1"G3'/55;);E"H.4>+/!./-@
@r2528
NNNGNTAGANNTNATNNCNGNTACNATCCAATGCCCNCAGNNNNACCANTNNNNTGNNNANNTGNTATATNNNNACACANGGAANNANNNNGNNNCGTCNNTNTANGGGNANNNNCNNNNNNNTGNCNNTANGCTCCNGTNGNCTNCNATNNCCTNNNAAAGGTNGNNACCNGTNNNANCTGNNCNNNACCNNNTTANNNNNNNGTNNNANACCATNNA
+
$!$!#"##$#!!"$##"!$##!"#!"!#$"##"$#!!"$##!$##"!##"$""!!$$!""#!$$$!!"!##"!"!$!$$"#!!""$!!!#!$!!#$!"$$!$!"$####!""#"$#!$!!#!#!#!$""$$!##!"!###!$##!##!#"!#$$#!"######"#$!"$$"""""##!!!$$"$"#$#$"##!"$"#"!"#""##$$"$#""#$$###$
@r2529
NTCACGGAGTATGCCGACTGGCACCGCTTNTACAGTACCCATTATTTTCATGATGTNCTGCTGGATATGCACTTTTCCGGGCTGACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGC
+
"+%++(()*')*'%'!$!&!%*"")!()%#%+&+*!!!$!)'+!++%*'%(+'("'!"*%&*'++%()")++((!)+"(&$+#'"&!+"#!#&&()$)&&!)"%%'!"$#+!%+&$)(%**+%"'&+"")%'(&$&(%%!+(!#(+*(*)&&&("!$'*"+)%%$!#)'!&''!*
@r2530
AACGTGCATATGGTGTTGTGTGTGAGTTCGCCTGGAATGATGGAAATGGTCAGGAAGGATGGC
+
)$$:@00-57A.D"D>/'#1?G%9*9'7!8(4H@:@,H.FE5A;:#3;%&!3>F-<;?1/.C'
@r2531
NAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGANCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACCCTGAGGGGAATACCAACATATGCGGTGTCACGGTGGTGTTCCGGGCTCGTGAG
+
$'$*$*#+&"+*+!*''""&()+%#)!#%+++#!%&'#$*&$*$%!$!!&!#+%+*'&!%*"&&*#)+"&'%&&$)!'!!'$'(($#(%$)*#*$))!')))%+"#&$!%$)%$*($)*##+(!)$(*%"+%*+)'$!'*&+$*"%#)")+("%&(&!&%'*&''('!)'**(+())#*$''*#'"!'!"&$++")*++)%$&%&!*+$(*%'&)!#"&*''
@r2532
TAATCTTGNGNTNGTNANTNNACNAATCGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGNTATTGTCATAAAACAATTTAGT
+
(&$*'*)'**$(#'(!)%*"%*!!+'&"(#+$('*$%$*+!+'!+#&'#*)!)(*"$+#%*"%#"%!!$%"%#(&#)&(%#"$'&'(
@r2533
CCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTNCGGATAAAACAAAAGC
+
E@E!?C=<&@@(%B#@3;&:3.4@@C'(<&'-87&<"A2*G@&"D/.C.FG;F27,;CG8'4D6H:)+F0
@r2534
NTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGA
+
!5+G3#+%H)179:3%8';"0G>'&%,-9)0H;/+-1(>+)%3(<%*;'(:0
@r2535
GCACCTTTGCTCTCTGCTTTTTNACGAACATTAAGCGACTTACTCGAT
+
"B4&/><GECC>C:9%8=)CH%0B$8!'%D>F'0==7>86@4%G1F8/
@r2536
NGNGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGGCATCACC
+
&*$C86E0-*9;47DGA0C%"((""$1=88C<B7!2A/@9GE.*5E(E,40C<;#@5HA$8G'?8/>G:'5*2F(H$(B#A
@r2537
AAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAA
+
G/078):G2%$G"8-!"+76:9!<5+)?*8DHA2CHB(!?"8E@CHF3:@$/<CCA+(@6?@@B4)#.3E.G=2E;B89+EE=7GG8
@r2538
TCTCTTCCCACTCNCTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAG
+
927)719>23B8+27E8A7G3"6FG#(B2$GBFE3:;3F##B$$=($E'?9H74C"*!F.D7+$*%A./H/A6BB,4)E;@!2H,85)!20:@*3/D#F?"$G63H,(;<,8
@r2539
GTTTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACC
+
$@?=#HF08HH==H",$2.44%51!AA&CH2+<*8'/H5/>B1,6(,H'%B99>G/5$3>D/4<H5*5H"7$
@r2540
GAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGNCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGA
+
F5/E@.1C$C73?6G7E:$:2*7&/<4E<)#5,:26";&'H*!GB(,.)9)G$$'0?"?8E&D'G.?3+(3H1@16**190H"F';"%-246)*B14-4@&ED(:+'$HED
@r2541
AGTGANGNAGNATGACGTTCTCAGTAAAAACCATTCCAGACATGATCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACG
+
%&*&)!*!"&)+'*#&!&*$'+#&%%$&(%)+)&#)("'"(%!#(#'(#))($$+'$&"#(%!)#+(%%#+##+%%("+%#+
@r2542
NTTCGNNTANTGCCGGCGAGGCCTGTATCCGGATGCGGAG
+
#('')"%!$!$)+**$&+""$!*+#"!$%&+'*!#*#('(
@r2543
GATTNAACCTGTCTGATATCCGCAANCTGCTTTTCCGAGAACCAGAACTCAAACTGCACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCANCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCAC
+
&")(!+!&(%$'&!!(*'#&+)&$#&!$""))$"'**"#$#$%+#&%*$+(*&!)+"+#()'++#!)()%!'$"!"+)%)"$+++(""&++)'(+'#!&'&(%+%##!$*)"&)$"+&$)*$()$!')"'%$+"%&+%"&'%$%++*&$"#!)'"&'*)!$)'(%"!%+'""'%"*%*!$)%!(''**+"**
@r2544
AGTGGCGGCATACATCGCCTTCACAATAGCGCTCTGCAGCTGCGTGTTCTNCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATNTGCACCGCG
+
*+"%)"$!##+&!&('!%'&#()(#('#*%&#!+'!)#+%&&)*%&$(!*!#!'!"$"$!'%$(')!+#(!'$$&*"(%)+'(*!(+!(!*'$+++"&'%")#(!+!*
@r2545
GCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATA
+
C#B'#BD$C=1,=/9=D4)+8)?49;+.F##A(9+=9A-%)E8068(:AG(FE%A3@2<5=)A#(B-2<,8!;E2F>730#+E2FG/)<D(==,9@/B,6B7.1&,"-2"05G97F2=1C$#;)2BG9%1A=&D=755,
@r2546
GTCTGCCATGCTGTCCGGTGTACCGACATAANCGCCGGTGGCATAGCCGCG
+
5.H*57>#>4/48(@)7;1*213B%2#0+AH4'9.F"D52,G8?2H,>-"7
@r2547
GAGGGGAGTGAAAATTCCCCTAATTCGATGAANATTCTTGCT
+
6D225>C46-B>1@7F'6%%((DC2349=B+-$6%)06'#D,
@r2548
GATATACCGCTCACCGTATTGCAGGTTGNNATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATNTTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCA
+
(+!!+!))($!"''"%+))"#!'+*(*$)%$!*"$)#"&+!'""$$%('%%"*'+*&'+)"')%##*&*&)"'&(+"##$%%!$!#!$+&$%'*!()*#!*)+('""')&'))'##**"*$#$*#$!'&&'%"+%"(*&'"**)&%*
@r2549
TACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGCGGC
+
G<$:)B#+-'?;+*3.DE<&-9G3&<)60/@)/5A&6+#=C8E'94&=
@r2550
TTAGTCTCCGACGGTAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCNTTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAG
+
&/C82:71'28<21(-=B!#1BG,F'-/<!C@9>71FE-+>@HC70'&0B2!F<:D"G:<0H2'"?F&/$),:C8(EGF87*AC-58F8"&(:C992CC/=*$$0&7.D)-"4C?1>9*1"-87%G51/0(?->A/3$(%D<*!D&>:=+$
@r2551
TCTNTNNGGTACGNNNCCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGNGATTATTTCACCCTCAGAGAGAGGCTGATCACTANGCAAAAACAANTGGAAG
+
'&&(*("##"($&!#'%+&+'"$!!&(&*($*(!"#""&&*'%(*%(&%%&'%&$*&#*$''"**%&&)'&!!&%+!&&"!"!&*'#&+(&$*"'&$$&"&')(+*"+*!#&!!$()%$%'##&)!&(&)#
@r2552
GAGTCAGCGATGTTCCTGAAAACCGAANCATTTGAACNTAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGTANTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACC
+
'G$$0EH<)7A(15C5#=)0>-98:8(0'!B+1D<3:=5'H:84D:+/!+&+%/:1=7&'D+66HC=!4;C28,0'A?1H?D*B2;?@(.-'&"+;?9BH$-<?&51A/0)$"';%/.*HF$C%:4.A-H++%!>CA.6&%1
@r2553
GNGGTNNNTCNNATNAANACNANGNTGCANAATTCANTCNATTTACTATGTTATGTTCTGA
+
)!)!%)#)**#$(&!*)!*&&(#!%)!**'$"*)))!%*$+&%%'&*"+$**"*$!'+&'(
@r2554
GCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTAT
+
:6%.E%+A/.@%!8&EC:&49EH@1!+!C;H3'6&EGHF,5!1$1%$0.<-/9842;:#4@F<5>34)G!/8$=8!9B
@r2555
CGTCCGCCGGACAGGCTGCATCGTCAGCTCAGNAAGCGTCCT
+
0HCH=,F?C;!0,?'.A;#,7'D;"H"9#G=#-'!C'9784>
@r2556
ACAAGACACCGGATCTGCACAACATTGATAACGCCCAAGCTTTTTGCTCAGA
+
754E66=1H.E<84#/8;!6B*2D'*;&2$/2.>:7BC?+"&HB:*#>H!1>
@r2557
AATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTA
+
3GB(A"*A1)E@5(;%!#*=D4.$D1G);*6/4/$*H1,%%=%(!D%@E"6(
@r2558
AAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGGGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATT
+
$7!*1$A$(H6)3(3@."&B4.1DB>!7?4:%9$@711!46&@1='&5(86&C1('BCAE1$9B/F)F(7H0D8-6HC?E$7E5"G,;%#G7%H8?-H*2EG8@=8?3'1@*%1?!G3!F+;68+*;?!C';1H+DEH045"B')0?B+&D7!C;-E-%6(5?FHG.3
@r2559
TNTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGAGGTTATGGTTTGA
+
&$8$#=%:E.2>;98=B!>C>04"8@7524!D>;"%,.@<C/(7FH$%=44:C>=B@-:&+/!8&!)G.2B5C&E3(
@r2560
CTAAATTAATAGGCATCACCGAACATTCAGGANAATGTGCAATAGGAAGA
+
B@7)CG=FGC14+*FE8'G$>B**>:#.<6*&1)9$?;,9BF+,$<,H71
@r2561
NNGGAAAACCNCCNNNNNCCANANGGCNCANGNTNNNGTTNTGCANNAGNNGNNNGGNGNGCN
+
""#"$$##$#!#$$!!#$!"$#""##$#"""$$$"##"!"!"#!"!####!#!$#$#$$"#$"
@r2562
ATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTNTGATCCATTCTTTGGNACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATCTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCC
+
<@4","::$E$.$?>=D>9>'*:=81F4C$<(01)B;%&5,B>%=8.,*+4!15;,1/?8B"29.0B:&5H!%0?;D=:EDG*.&.'*(B*DH/*:1A>>2;C#5+%9+=3!')-7"?<'=/4)'B)'@$2@"6?<4)4<.=B*-*#&=/'?.DG)7#.8*4.>:.)'&1(0G#9@"@@?8-1=55>6D5=575#8DA2B?G5(EC%BA5'.'G;@%"378:G=1!*1F7*0:*(1<
@r2563
GCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCC
+
#::HC,?H.B>>5>1!>9#C)(E@<G=E0.94EA/G>6.#4F=
@r2564
TACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGT
+
@*81?!=2A0>=!1&A3#CC%3<G%DF,&--+<>E@);)D:7E45C+:&/#-B'%@""G$D!%H!A,;6$4=*>D#.8*-,$:5?$"6B''
@r2565
NATGTCCTGATACAGGGCGTNATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACANTCTTCCTNGGTACATAA
+
+&!#$%&&&)(!++(!%*++&$+'$'+!$""('!!")+$#(&))&%+((&('(!$)**&$($**!"!$+&#(&')+$()%$$&
@r2566
CCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGANAATCCAGATGGATG
+
%4-:C'&.,07D6<<1D?@,BGH#8,$1*37FA!>,(@C>5!5<A-G?$487:AB%)214-"2("#4;@:D3,8A=/2*2;84#(27.&#:D@(G&7D$5/0"7#4"3$4-A209F9B?!/#0-0!H#>/(!>#6-:>AF1&&5>7=G%5D)'';>$75CD6!H:DDH/;,()=<HE"
@r2567
TATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTA
+
7DA79<5;A)(0-B8:B$G*+-0<3+GD-5B6A@/<4'>?;=7!4:B7<?#*#.91;@G*H'2?4130"8?#>19CA65<
@r2568
TGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCG
+
.C?=*C">H#(:CG2!":&@B5A8AH:4;*E!)+A?D0HBB#$E5."6FF0,#;H56
@r2569
TATTCCTGAACAACTGANCAAACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACAC
+
6B*;0"AA&.@0CF:@(18033<D3";)E<EG')02#'0EE$#G'(,.>,+)+7#C<&8;7
@r2570
CGAGAACGCCAGCGCGNCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCNGCAGAAAACAGCCGCATTATGGGGATNCTCAACTGTGAGGAGGCTCACGGACGCGAAGCACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCNCAGGCGCG
+
>?3@741?##+6%#H0'6?7H8C""=9.4*;=3%$&,D6><:7$"@!33H.A=H=&&710=E#'"F6%&:=4.E"'9BC6++-9/>.@E<09%8D8B?.C41!(@F!?2+'-5$?.3%B&-+66/"4>8=9$49;EE,';44399@1;C"407%>-E,6&7%B+-C>>9(("/1$+(3B@B';!@F@'3E$B7*5-F5-5*4/-$6.
@r2571
CTGGCCGCAGCGCTCGNGAATGATCCAGATTTTGCTACCACCATGANTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGC
+
<&)>8?='55CE7)A/,AC;=(GCG,%37!215*4G*7:%-74%:$066F0;$"4;=3</=#*5D81@@GB6H17-GD*BA+==D?.=@.E$9C->8A7F@%&
@r2572
TCCTTAANCGGGAAGGCATAATAGCTTCTGTGCGCCGGACGTTGCNGCGCTAACAGGCGCAACAGTAACCAGCNTNAATCAGGNGACGCGGCTAAAATGG
+
#$$'$'"##*($#&+!#'""%$#)&'&)%!#$#&#&#*)#")'!"%&&&)!(%##+*"$(#%)&(*&#$!)#*$!*'!"(!"+%$($+""#%#+!(")&"
@r2573
GNGCCNCNATTGCANNGGTNGCTNNNGNAGANACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACA
+
!#"&$!(!)$#!*%$%%$#&))$&#"$!"#+++!&(&$*%&)$&#!&+*("#!)(*$!%+!'%%#$%&%*)!("!"%((#!!"'%&&$)***)#'')**$"&!%+"+
@r2574
TCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAAACCCAACCAAACCAATCGTAGTAACTATTCAGGAACGCAACNGCAGCTTAGACCAAAACAGGAAGCTATGGNCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCNGCAGGATGTTGTTCCTA
+
@B&!.@'F'/?B$FF.-#58(/?E8<$(@D5ED0;!+"HEFB0#:C30"2<9,")F)C!CD-!.>9@=#+)<-627;2FD7)?.@?GFG#EBE1"@%++A9.-H+BB/)E*0/.$7@"2%;$.-<!!H$54(:#8G61E@%=@+8!)??B,5#*(==";E*52B%;$.3CG7/9;!@&+>/'8D&465*7/F(2/!2!&$2@3)G9/C3H1GA4>;@*:.%G./(.'%6G?F3!$2"93
@r2575
CNGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTAGACTGGCCTATTACCACAAAGC
+
*#:,1)5&AF,A78.--)$F!/3<-G'92H4D4>EB<G=9251.75E-(<.)+H(C1418#A'0/6#<+>/HBCC'C*A'+7("&F:>-DH%6/'+$*!E/8(>&=&)
@r2576
GGGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATNTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAG
+
*"/48?HB;*8(<A-?!)$%>#%;<BH1=.20BB5C8G.=07B55/H-!!>+/*99%*A$7@&F&45?-6;9),65A):4>&/=/1G(?@2"=&2!7)63;C09#$@7;//)2C?4#E8>)6,H3F68G%(*%!2@H4,3B'>BE-74=&C8A#.3<D4+8CA<H+&?F)H(==51B3CD<1/G9E?B%7'788<;5$C>*8BD<6?2::26B;3G4.!$D:D;5C%;?&GC(*5&+!'/8/?DC=-D.B*H%*%+/<9
@r2577
GGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAG
+
-=4<0?(%&#6%0D6@?,FGFF6%0&?F>5@$6B'5='.GD.<"3A#'=4'8E3H;G%D:6H@+-1F#".7:@97EC+>?11-9:7<C<.,251,!
@r2578
ATGACCGGTGAAGCCTTCNATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAANCGTGACAAGTCCACGTATGACCC
+
2$F)$A1"?:<H@8A@C"H"'D8D!"4*GC6(A+9'E&C&D3D()%:9$#F!5D5.;469<++-?,.)4&.96=2/(?9?C?;1&.-?*#6F7*)"<>1.#&',"-.E:HF(;>*@
@r2579
CTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACANTGATGACCGGGGAGGATACNTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGNAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGT
+
,"8&?!'CHB"%'-/H(C?.;4,D>6$">=*?9C9'F*7;8*23GC:5HC@.<!H+#4H'1897DG#06;E%?'E(?E94HD0,0=7/=7G>(:=*%EF<.*.A/9->85B;&)#B568#C'($0&/-':+%"=4)=%3*#@)3:H904A*.?4!<1"3/E5BG&$:(.D,$("$?F*#)FH@';:B1"?$/3&:)+*89$01(2-19-,5?!?$7"2DCG.6(B=2>8"EAB!.!7,%#E5=4'!6ED1?.3<0;@$G#CCC(*%0*;G2",,&#8*)
@r2580
GGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGGAAAGTCAGGACGCTGTGGCATTGCAGCAGGTTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGNTATGCGTCAGGCAATCGACNGTTGCAGCAATATCTGGNCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAA
+
3&<?*10>>(:H;3*00?!@:).HEE1<$$#+7#D+70*))B/%5=,**56C68G$%#5%(9@!=51(6#62G8!-,0/%+6AAA>E457?"H,-9.)'E8)G6,$/;1C0>(0FE-**@*A7)0=13#F(BD%A(=,6G2@,3@."9((F*(='H3:!2;9!)5-0$CB72$5H'1=%6%$G;1@4B/'B+'&-23H%/')(49H.+,*4*2C#<>-AG6911@&"316:<D!@";#F7:2('6%?8D!.#G-)BF5)1-<1(!G/"-7$")&=,C)*9<2/$=H"!F=H/;A2&4$<0C1+/!$"&0F2$G$C*0"2&%F476C34*57-:A!<$2
@r2581
TGCATGACGACTGGGGATTTGACGCAGACCTTTTCCNTGAATTGGTAA
+
3'4"-60)GF:D8/#<6@E?081A1E4=7:;.+&841!(-7?$$HF%>
@r2582
TATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTNCTCCTTTCAGTCCGAACTTNGCTTTGATTTCTGCGATCTTC
+
35&E):;54D5>E#?9!?G.%3!H30<C.@H;H%:#!2(H:AB;B01534.-F$86-C4;<A?.@+"";5F<4F5)0-!#->6#)2'.FEG9(%
@r2583
GCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTNATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAG
+
)-45G8&,F'8E*$.'65+89<+:>=C=<7=B;5,D=EA9&E7A?89!-&*/(%,@2<@*<"552&A"9$,)37"F*&'B975$=:6,B67@B+<)(;2<9/7&#)A/'/9),.;?*F@'DGG%1=>C/8.0;;6'5$>)8.)A6@790F1,197=.#@=*2
@r2584
NACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAA
+
"/%*DH(5?0&*476B/,EF86.!7=H<@!A3/2DE3!%/8*<-#.AG/8
@r2585
NNTCNCCTGCNGGATGNAGNTCTNCAGAATCTGNCGGACCCGG
+
&$)($('')$)*&%#'##*%$)"!'+'+!$#*#&!&$&'*%#"
@r2586
TCGCCANCGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCANGTCCAGAGCTCATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTC
+
2B0DED%&",')?298*3BEBD6>;C)!67-4@+18H6CH@&-$&);+.';18;9H82+F5.B&6<#)@'%5@#+4E6"$;EF2%0$-:$=/7<,4F"CA:BD,<?&/B)$069E>"4:
@r2587
ATTCNGTTAAATATGAAGGTACTTTCTTTTGTGCAAGTCTGACTANCTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATG
+
2"D;"BB;AC%D=E$+$#=45=E@<;%G;?155!D.)F#HA16A-7B:=(&G?+80!&21&<6$8G;BA9:.1#(8.+<7@%D85?/D:@,+7GBF>D9*H!,>2+3!)?
@r2588
TCNCCGTCGCCGCAGTAANTTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGC
+
2"?"0!0"%=H,9:>'(E>7A7G)>>.@*;,93F/1>0')@>=,H:*GFE%87D;$&;!<+DFB4BD'$'
@r2589
TTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAANTTCCGCTGTGTGCCGCAT
+
H>17@*$CE:5/"!>3G:-!6-F=%C)(HCADAA(0B==@D=+452E!""6<G%'1F
@r2590
TGGAAAGAAGCAATAACCCGCAGAANAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATA
+
74$>;<D,A9H>;,>E>/>980,G<)5!:C(1%@5'H&69(.)C=#!.&B@00;"H77*'1
@r2591
TGTGAAAGGGATGCGGCTAACGTATGANATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAA
+
/&(<)5AH-)??+.:@D4?<<HH?DA'"4=;HD@F>)6*.+$;AD?6(#=D#,%B>G<3*@E!4G3!,+#F=A#6:D8$))&
@r2592
TTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCC
+
H,#0')40='=5*<#"9&9.99:.-/#*7!:6H5*F1">"9>77:04@7*D"C<1AG#=-<(7)8B$<$EH',-:!;*4)H?D9#E$A#2:8:1DE<4G>:
@r2593
GGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATT
+
E7#:54-?.+&6"!)0+B?"#1--+G;H8!%D0.)(F<>C/(4($$H6
@r2594
TGCTTATAACGCCGCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGA
+
9:-*-).70#*:<#H$E4.,1@!!4+7GE$;#3)56#%;4&'-;E"EH6C1G8A'42#<-0>$;637)@.D?8@$63*96=+*$<B:*B->?.F?75.C$/F(G/E6<5C)'B538B5?9:&4'/F
@r2595
ATCACTCCCGGGTATATGAAGAAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCTGGTATACAGATTANTCCGGCAGCGTCCGTCGTTGTTGATATTCTTTATGAAGGCTCCGGCAGTGGCGACTNGCGTACTGACGGATTCATCGTT
+
+"&''(()'""!+'"##%&#()"+$'&')*$$#*&*&%)%!!%$(!+"''&'("$()'#%)$%*$(#)$$""$"$*)")""!)*+(%&%!$$$!*+!()$&*(+'#!"($)(!'&+!$)'#*+!*+**&"'"")"!%+'%"#+*#(+!+!%*!&&#&%%%#$%+%*+(*&'''$
@r2596
CCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTG
+
/"C.0:):$*$C-)@#)1%?@H08!3:A!-/G9@F1$"5,?B78:,?$E.691%H2#DG--8"DB(A(;GF0$F;
@r2597
TGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTTACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGNTTGGTGCAATCACTAA
+
+*$!)#&))!!$%%!''"*#%()%#%!*'!&$&+$+(*%"**)))((!%!+)&!!!%'%"&%&*$#)*"()*%"#+$*$()#("'*$&#$&*"'()+""!$##$(**'#'*"&"!#)!)((%"'!+!++(&!'&"%$#((%*+"%*$&&"!()+#!$!%$%%'+)(!$+%$%$)%
@r2598
CTTTCAGGCNGNGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCNAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCGACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCT
+
.F#.ED&GEC59'>AF07@$!$<F94;B8@$?%9A17>B<>?A?7->,"=H)>+.E-1"'+)6;3>F"$-)37-/4-B594A0D='*3,=C8!4)30,D)8!--9(7A:8!(=;EC9/)4"="7!E>A808756C;G;)B@C3<G*04(%6<CF'50:#0?D!D+E8>D;48E3,/%C<?H4.5A9;'!6+@0>/H8>1>&!='.5=@2*A@G?C3$>:-CG$1,*FD"%5F@5G/;F;E4HB$2'-4A.FB12.F153+##,<
@r2599
TCGTCTGCCAGTTCTNCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGA
+
:!*$"%=*/C->(%AGE6<,):<5&9F?.6!=A&#D9&#-05;7%+(G@+A%F'76!"06B."2:?8#$?/F>09
@r2600
GGAACGTGCCGGACNTGTAGAACGTCAGCGTGGTGCTGGTNTGGTCAGCAGCAACCGCAAGAATGCGAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTC
+
07.#3:B'"H4-%&=G&&%:6*2>@,$"E)0)A13)*>&=9/04?'>C@E<*-A9E&,6?#E!6E%D2!G;+=5&63GA)?,"$=D0?><B*-)8G?2>!'!H&=;6F.?*03&0*0?@<"8.477F,+@1<5E*-6"B2G%H/7*66>A@8G)EF2(6'F
@r2601
AGAGCGNNNTNNNGTAAAGGCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTT
+
&!)))$"!!'$#!'')%&*++&*'')'+*#+%"(#**+""!)"'!#'"#!(&$'+$#"''
@r2602
TAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATNGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTNCGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATG
+
CE8/D8*-'?'H6,#!C6+H,>>!:(#38"*6>+71.<8)D&E8D7*%5@#-A5=A$*5:$B)3*4@6;%/@8H+18@BH4C1?9,.&20)"&B8=%)=7D8B501"&+3E'D=<;(.HA9G0H#"!!C0B)+)+:;3$G/8FAA4+<.':&247>/+/,#&>>/6)6+5*$GC%$1C*%E@/A1+1B?*:<#;@*D'?H5"-7H@/$?!//$D*#;:8&%2=15*,.//69642)"4;::8+H0CH-.4'#A/@AH3'58HB6;=671-C><1%6$@"$468)"24$370G&0*G"'C+E3%CA.0)-46%(FA==2C/'A:G/D0F,FE/
@r2603
TGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGATCCCCTCATCAGTGGCTCTATCTGAACGCGTTCTCCACTGCTTAATGACATTCCTTTCC
+
4::<7?%D#,6'>,)=>%F7H/:>6=0>6>F)4;A1C()$.=.%78C)A'/?71E:-;32C*$B9:FE*G3D6?AH,0E.9??*1%)'0E5,D!H0DE2*7-7*.!4C'=/G@8#<<G<A-<8E0@0C";'8>./3=E:/#(@C<G(6D!EH;-;#!'8.+(>.&;#7F&9$F8!';DC=35&@BA"0-,G<.26!*6-3;"9/=&G.;@<#4@=);:9A3?!.!93(:2%;A35A>4!->2?6,2
@r2604
GATCGCTTGTTTCCGTTTCGTTTAGTGCATTTGATCCTTTTACNCCTCCTAAAGAACAACCTGACCCAGCAAA
+
*F<%;'A4<H"@$'7&=E2735+%(0G2@2.5DE'#-:2?$3H>!+7<C"H#*'?30/!&)C;8"9-88661=
@r2605
CACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCA
+
B>:/>3@,8>H*67HFG<(.'3!=60DC$>+923@.(=5E3=-F6D'?<<?A8316";*?6>!"45,=8*9!E($3$((0>-><&!C'F5E?4C9.%F7%%;);=?.;FEHD/%5)<#8AG5G0."@9!26A-C92'77'$
@r2606
CCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGATTTCGTTCATTTCGTTCTGGTCATGGTTAGCCAGGCTCGC
+
4*EHA73&)#A*4B-$%#!<,8:E'+7:;3/$=<E03*+E#3>67#1$0,)*.60=/6=,">1?,20!AHHG1::C4>
@r2607
GCATGCTGGGTGTGGGGATGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTACTTCTCTGGAGTGCGACAGGTTT
+
<6@;'?'HF13#D)+08C(,<#)9(%>>4#=G?G3C,A@+7514?C=A67H;?194A6+%$/,D$D87>6E!3--'7@9$81'47#0%B*%4F&A=/5&+;H>F&9)#9+@451,(;"@2=0$/3C"%1&H:;'638A(:;0EG<6FH:78:&%HH:G
@r2608
CCGCCAGCAGGAGCNGGACTTTACTGATGCCCGTTATATCCGCGAAAAGACCGGGATCTGNACCCGTGATGGCATTCTCTGG
+
.9A,<G-?6?+#&F-&B9FBF8+1(B)$9-,042/91)-(:@+?2/>:-8766#+9=+8$19B:8.CE%B#A$"')H7@8/!
@r2609
CTGTATNACCNTCCTCAGTTGATGCTGCAGCGCANAGCCCAGCTCTTTCGGAAGACGTTCACGCCGNATCCGCTCAATA
+
*%!$%$#*()!+**)+%!#!("!($))+)%('%"*(#%!)("")))#"$&")%"!&!(#"$'%'("!"*(""!'"#!"!
@r2610
CCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAANGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATAT
+
%/C$>**565'@A=/4;,$G;6-:9&$>&9";87#(+#65A%F6*C6*/?;A@<%-=,(6CE("@4,/=6E:%,7@F@F%G&)CB=FEF@
@r2611
TGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTNACTCTTTCAG
+
8G1>AD9","?BB*189+.98&@+."GE@-/;7$54#AA<>3F9(EEB+6/@#DC08A/DE7,(C"7BE2)B;A)!
@r2612
NTCGCCTTTCTCTGCCTAATCCANACTCTTTACCCGTCCTTGGGTGCNTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTANGTCAACCTTTAC
+
,A/&>%F#'@C%('?H#<5$C>-?B!1+AA>!&&EE%09H&!CD38.<!,F(812:EBDG$05D5=9>;0//G9FF3961=@1B6DF/G5<506/)/31G*C/=<CC'/=HDE3.)H2A'&<D>E'F>&5!+:54;.C&$7=?CC34>6<3DHE;0@:#8'E4#/9"HA;#F-E5)30,2*0
@r2613
ATTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGANCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCC
+
$&C"D##*%BA'@/<3C#A%E5-4%GG$:(#@@B410:,8;-91=2%D5/-(DA=%DB*=)<50/6&GHA&;<=A4H0!&5'?1E*00>$A.@/%+D;3:*E=/'2DH/>D?''";G=9-2(/0.;0*=#."H*B8!-@4*E-1=.BDB6;"14+>=@%0G3E>9;,&614"D)*<8'$@@9<GE:2E
@r2614
ACCTCGTTGCTGGAAGCCTGGATGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTNTTATCTTCA
+
))3$-&B!H9)!;H/A=!-@>&#2@E37#D=%D1>?#@;,G7.CA6D2)=)%3>BG,H>7,<AH2''6F@25H9D8<:4=712=!1G*<+CDA,+G=06?3#/"'*C2(-:A3;8'/?#;$.%&@60EA<:.'@;C9/8!6+1D9#==@<F+'2308:#<%+#$&2:!=21/4#98!;#2B,)-;$E4#(#.&E>9H6;/&E,7?*D(
@r2615
NTTNCCGNCTNTNCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGG
+
"%*%)&("*'!'!+)%#*!%')%$!+%%'*')$"&%)#"!##%++%'*(#%%$
@r2616
ACATNAGTGATNTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAGNAAATATAGTTCAACCGCAACGTTNCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAAACTATTA
+
&(&*"$%&''&$+#$##"!'(!#!%%+('%#&)*!'$*+**'$!*&%(%#+**$""!(&$)&+&!(+(&!(&$*!!&!))!&"((()))'!&!!)(+'#%*$'%$!#&%!'%$&&!('+!
@r2617
GGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACG
+
;4GA2?B/":&A+3@A6A+'#83(6A8%DE4?99'(<.?<'B51/<;DE'A-6$92CC=.>-&D,26*+D!%8/!B8@-!,@37?-309G
@r2618
GAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACNGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCNGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCTCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGNGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTC
+
;1D!E::5)B@$DH17&'61"%>G#%>$;:6H<>F9C288AB10:H>"H9%261>>,9C6A9F-;#%F+,-=E&"8G3&BC;;;;(3FB>&*>G>H!4E?(/BED0=D9/6!0;*&;&)"EH+7,191HH#,8E3%66=9%@8E(>'E%D>@4C+53+H")?=,@(=6";!24,FFD:9.2C?<@#@*>2!5E7$"?5G#4+!''F2?$F'=9A#9(C$-8.<G."0-E*@5H0,?'""&>/<A;/";-#@ACD#<:'
@r2619
GTAGCGGAAAGAGAGTCAGATGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTT
+
36>$6064520=672)7=,A:B"):C>&H%(@'5F-#997%;A((3@H,!;(#;#15@:3-:-?6C.4;@2A&55<G);'4<,8#<GE9?8(5:01E@F0:8)&2;-&%17#FC-(.A*=:A4H/
@r2620
TCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTA
+
=42E-(F.9-0D(>3+C?F&<*B",G$?*'6'C2"59$<$.@F(E)02:
@r2621
TCATGGCTNTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTTCGCGNGTTTTGAATGGTTCGCGGCGNCATTCATCCATCC
+
EG-2@?*+E$<02"D*/".%%=?7;?09,5!@G!G=7A@"2)+F3F4(E%$D!D5F-G-90"99.%>8(-GB%)E:/+<:@!B9E2%"B"6-,%>5)2HH@C*-;
@r2622
NGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTGACGCANCCGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCNCCATCCCGCCGGGCGTGTCCATATCGAGCAGNANGCCGTCCTCCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGAT
+
(%&("+$'$+%(%&*+"#+)")*#!#'')&*#"(%&*&$+&$!$&(#%%+++)#+*$'$+&#"#%(#$*%%!($#%+')'+)")'#%"(!'#)!&&+$&)#)&#&!*+++$#'**#'*&$$%)!+))!+*"*&)#*"*%("%*'*")+$'*&(+$!!$%%"$#&$*$!$%)($!#$+'&*)")"%!+'#+#)&*&)#&"*)*!$+"%))$#")"*#''"*(%%$)**'*)%#
@r2623
ACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGA
+
,432@1/45HEF+E*9/+8F3A2&=6G(9&B=G&9(3&+2(46D',8,(!*5G7+CE8H3*8)<05
@r2624
CGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTG
+
=&'FF)"%:C7,@#5<.%,1A3A?7>!@7F&669?&=>"1&B3E;1'3D'%7+&==8*2D7!,(6($&"%?+90,!)!#/24!:<!=E!H8B29B=9&$3?0"573"/,2C8,
@r2625
ATGAAAAGTGATATACTGGAATGTTTTAAAAGGAANGTGG
+
+))%""!$+)#+&"&&!(***(*(#!$&*'*%'%")(*%'
@r2626
AACAGTATGGCGATAANCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTG
+
1@FD/1+%*(6."4+)/:*<%-'G'<,>':%0,-#$))49(&D.G(;-<0#4<EB)/D'4>5H%*",,@6$#85=E;7%6D11:=><B87'
@r2627
NTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGNTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCANCCTGACGAGAGACGTCAGCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCNTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGNAAGGATTTGCTGTACT
+
#)($((+"$&*&%++)"&)(#*$)%#$$!#&('*)*#)%+'%)%!&#$+**####*""!)%"+#"$"!*#$!&&%"*"('&&%#*$&$#+("%'&+"*(*!"'+'("**&(#%*'*"!(!%')"**&!"+$(%'%$))&)%&'$+)++"*)"#%'&*#!'+"#('!!*!!!(()*"%)(("%*#"%%)&(!*++&#!('*+""$(#$")"#'%%+(#%$*)"+$$&('!%'+((+$&'
@r2628
CGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATGTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCNGCGCAGCTTTTCGTTCAATATCAGCATCCCTTTCGNCATACCATTTTATGACGGCGGCAGAGTCATAAAGCCCCTCATTACCCTTGCCACCGCCTNGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACNGAGAAAGGAAACGACAGAGGCCAAAAAGNCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTT
+
F";+8(88-?B!3<CG'9"%2=0'!?G14%GE/CBH01:A9;5+8E:26HB%,4DC<G=!()0@;7*%,@8/B<H/!>3=A)D%?3H%<)*D:.&6:+>E*C1>B2'@G:27./(/&,,9/&A+D:=.G?.4"2EA0<E:&9.49-(&(":1.G9B4)/-$7)"@6>2H-$7H60AE8!;B'=;(G10CG,'72@2,6&'@'/448B;B%!A@=><1EE@(?F$,9/264(G),#BF('0$8"6;";(H.A54,D-,2;(,18'3-44GG!@=FC!,:2$=D)&0%,A->B.4E#!C#9$5'=!?.63.=A(F5F;D;-7'88<B;)CG)*('"3F=*=E#E)7F;,9E,7.7
@r2629
TAACTGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACT
+
<<>H15)!3+E"&"H+=+8<(2&8H?81->5B(GF9%2?EFE247=8GC2=9>9+53)0G'.H$!
@r2630
CCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGNCCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCC
+
@,>9=#'6)B.E5B4(?F5>!9>5&2**,'0@/:HHHH,D13%.D))D01C*C87?H1%A@-C(:;++)-7=0?853H5>?=11$242,<D$=-A?62--&EBE91D
@r2631
GGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGCCATAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGG
+
%+!+"!"$!+&*)"('"*&*#+$%'$!'#&%*)"*''#$!%+%!#'()"')&%"%"')(%(#$'')$(+!()%$##$'()!*#+!&*"'(!&""!(*"%&#"&##'&''!&'++%&**+'!+%$
@r2632
CNGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCNCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAANAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCGAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGCTCCCTTCTGATACTGTCATCAGCNTTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCNCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGAACGNTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCAAGGCACGCCAGTCGGGTCACCCCATCTCTCGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCNGTCTGTTCAGGGGCATTATTCACCACTAACTCATACATACCAGCCAGC
+
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
@r2633
GGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTG
+
,G>/#F?@8A'1(8*@=H%C2%A+6)+$4"%>>*1(9(#8#H8CD33"609C<:8/!7.G,'5#@8G'"F1,3'!C!E8::-6(E('5B#F/C-
@r2634
NNCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGC
+
!&(F2$-@=>:#9!&%0(+H/5&(!>-9+F#G59E<B8..>-2C97:5(0@1EG369+!-DH&%5
@r2635
AGTCTCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAAAACACTGCGCC
+
$(D&$7055D@:'.D0*2=AG.:?93E%(G,+*;-@9E:@2?;ED&*6=*C;<@D%34@FB,*<'='H?F$94GH@A8'.7*%D0!E@7(@$3G4*@+-')-#6/-=H*13
@r2636
TTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAANTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTA
+
<+:60$@+2F*3-#.)D"5G@G9>2;"E7/!!;F>E>C$5.<,ADH8#4-.*%09=*7"(7"GC;A8H*+<D1%'-A%B,.+$;CE7'C0>7/C-*&6)B!D'F-G$,8@+C)53+H)21%A<H139/BA0%;57-2.*H=!.&H8D7H'90.1H>=52<'A@@2&D:(392
@r2637
CCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGC
+
**>&?@??=2F1,401&5GED,A@74'@&-G3G+2-".=B-GCC=GGG;G)+!7A+9;&*5::A*(B.+>F
@r2638
NAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTT
+
!B8"?0H1!G?56?H,73+(E#C@8:2'&H6:BA>:>AE><E0(EHAF.:;*(</%HGC*E?'D7==A#
@r2639
CTGGNNTTNATNGNTGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAANGCGT
+
$#%'('!)*#$"('+&"#$&!)!!"(%*)&**#'&&"(##*#+$*((''%*$'""++%**"(*%()*"#*)#!%&*!$!#
@r2640
CNGAANCNGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGC
+
!%*%#!)+*(+"%"!)'(#(%()#$+&'+&#%###)#+&+
@r2641
GCAGGTAAACGGGCATGTCAGTTCAAGGCCGTTGCCGTCACTG
+
BDC1+$?>(87"B1=0AC):'1()(HG:#.!42#&F7GCH(-A
@r2642
GGNNTNNNNNTNANTANGNNTNNNNCNCGCNCNGNNNAAGNANGCCCANNANGGNNNANNNANTNGNNNGGNNT
+
#!"##"!$#!"$$$"$!$"!""!!!$!$$$!$"$!!"!$#!$#$#!#$"!$#!$!!!$$"$##"!$""#$##!!
@r2643
GCCGCTGTTTTTTTCGCATCACTTTCNGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATGGCCTACCGGTTCAGCCATACCGGACTCATCCTGCGATCC
+
09)/0C?>H)/:D%@C+28>GC.AF1H3*$(?>HG.,DA7"!/!,BFAFC/-;.;>58?!>%)G6-<:("0D.'915:A=#90A)4);3DF>5ADF"G7?=05%*>-'5F&:(&%5)-'>C5(B(C+:<ED@#,*=/;=;)4(5E0
@r2644
TGATCCATTAATGGCTTGGGCTNATAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACT
+
F=$"1--"30$(G",5/:F4?A098$&BC?+*0<>E!"4E!&;5-3'#/AA&&5@,::56=@486.%?3+A/>E<08@0,.,9!50%!FAG<B/+,1/#%D89D;57D5$FF7,B%233'3)H2.A7>&F):<&7#8(@@&7!A=D9+.692ABGGH6<G:-!35?/5;:)3G#7.#
@r2645
TTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACTTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTNACAAAAACAGTAATCGACGCANCGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAG
+
*>>,8AC,&,E"D!:33;)%B=:D>+:HH/90'G:(4AB*!G72FHF1<@8#HA#:*761A(:GBG122(4,(G+72D"07)E.)2/=FC(<&"$=4EH?A)",87H6A>0*A=(4&H@8AG387&?-8D4($:-,B0"DE)>=,?84&%6B?10?:&!),A-D/')FC;*"1G>8=-(")AF<3'B(B9"@-<(.4:0G8%$4@6-#$AE<F;55-AH(C62C*G17&&)+=$""86-<B$=*3)/6A=EG;-C,.:E97E%B81$9!843:6E?1.,/.=?E#AGC?&-0&.'3$/#)":&;D#DDC!)=(3",*F,"-HH587#-=-53CBHE"8!B2C3#?92=5%8(85(9+')!:<,*>B773E<;**+177D%"/&B2H$:=:/GD67D)=C<(2>)D"'$GH,-$,3#/H?79?/H9)>6C)B1()#*=F:4AE"+B>@!<+,)@C*$1H8#$?=73;.0<84EE>6>"),C@:?-@E9AD64$
@r2646
CTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCNTACAGAACAGGCAGAANATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTA
+
1,92G#&7$=@H=&3.."'AC)HGH7;81E/-*#.=1,;9!.;1$H)40D+@42883%<-EEC-/C"5CC5$*EAE>?5A'*2AG@20EC63H2$?H62(1'4@.$"#!4+*$1"F&D#1F:!1-#<H=.88@!&!3D+,0="4G?E05"":7&652*7F.?0@"6,51A'9;?D.!(*C!,-+0E&/BAF6/8:6"""@7?6A#)&="#&?,5C,3719,22GD(9"*!-C+B)7C98?
@r2647
AAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGC
+
*F;*83))BG6,(*9%)'CH><'<5=!63B"%6GA%)&0,*,>>2B2>5-(D-(4/E/!5H(F8C<&/"<EEF;.A#$/%:?$%0'&@@<)-F0/:.EG*7.7>5)F1C9'-+04H/)*&F+H)!@.&<,1AC7$&+A@4;!,B?8(71*'9=A@0=F6H=E'@!:&)C&-%#?7G8;*!-9E'(.#.B8>
@r2648
NGAACGGATNANCTCACCGAAAACAGTCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACA
+
"#$*)&)*%!&&&&&&%)%$*%")%#+)&#*#)+#((!%##!$#*"*(#)!*'(%#*&"&%+#(*&$#&)(""'#(!*()%*$()&+*$&!#$"+))(#$%+(&+#%$*#*#+++&'%%"*&&+'&)!##$
@r2649
TGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGA
+
89>=9092?0!'1C+4;4@9@-5/6(4'E@7DGD3%9.#4C.!':@6@A3C$%42D45?$%9#1/.&A:>C2/-1!$=;9A9-;'$<('<.D,B#@0,$%!&B!?+:&8!(=D<."3E(8@8)"G0E5,4=63A%<1&*$$>6$%F8/2?FD.<-%D&,6'F*#=?91F+6E<(287$F421&#88G!@"$%DG,@8,-E.&29:G697A
@r2650
AAAATGCGATATCGGAAATGTTAAAATTGGTTTTGNAGGTCAAAAAGAAGAAGTA
+
14930CH=F241A?1C>1/:#(B;2$+1>&24<3@/6.882'"$:D-;4/31D@'
@r2651
AATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAG
+
=E;#=:3A$+B&!(%/+C$%(#'"(-@GF>F"86$**D5@(6<4'78#0$2*=-9*A+,E$AC3/"0A7@?!(3%F)'>.;'3=(;=8,,F&%C!A1;/C
@r2652
TGCTTATAACGCCGCATTGCTTGCAANAANTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTCAGAAGTGAGTANGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAAC
+
6=.=7;*=-E/%-;E@#6GB%HEG5?$>3'F&:?;.";2+H9D:+55A0&F3$6)A));/#!7-BH@EF1.1CC$?-'4C68%@@&H/*E"C=)68E123@"3''HD@B,#5(9&D>=*94':"HC&'%0,4$5!$5"8%3=752:>E"-4+1&ECH$5H9(C@?%5)F)"16HEB+A.%9"C*/2
@r2653
GTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCNGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAAC
+
F)A+A82D&)5%,<%.8('++1%."EC-)316<<!2!+)6>-,4C7D82;C.36)<>08=$329,#(B=9("<!"A/0(2D6A8&(';E,:18ED+%.FEDC5'+:E>@/97&*5&=))*6A(0EA25D.<
@r2654
CCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTAT
+
H1)*@D)(8-*5!::?7**CAH67A).5-,G8A/-B-67&(4,#8=%@=BH?H#,6+!&822=6=D&!*-21'+$4;-=*(%D1-"#3.-//(#8639G()C?(""(?4E:&;<'<7$;?8*9DH1&C@B/(:(>2(5@-7A=2'!A$A@+=(G-$(=#%2/!"C;?,D
@r2655
TGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTAT
+
6)D6&<46=':'C1!<,')$:*F.A(0G9//!3$#7&H,C"'&'2G9D+E:-C/$9@C25;#5>$>7E5/HA
@r2656
CCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCANGTTGCCAGGAGGATCTGGAACT
+
?@4G>691'"@#-H>785GB557&0BD0<"&@F8&%F?-"*H';)8(/>#+A&.)4/.!?=B0?6E;>592+(B59>!.&8:C7AH1;G7&/:7>0<594
@r2657
AGAATGCAGAATCACNGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCT
+
-->G=>'H1E$B)."*<":,(0>E/0>%,6%)!7BC&>G7.B(;A(#C;$6H746&E%:#:1G.;=7D00
@r2658
NCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAAGTTCATACGTTAGCCGCATCCCTTTCACAAA
+
+&E%9*"C()'98G:)!*64*'40&.50H!55G;G&1"<?-$1""("E9*4.&-/2>F&?D--C271..'82AD4'>2?":%A"%"=5;++-6%
@r2659
GNCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTNGATCATCAGNAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACG
+
(#EE7?4;H%5H>3.C9F'6?3"GE"-&&!<>8>='E23"7$FG"$D+%1:C9#>!-1@*8'1299"%!23*(5'-85C7#B$D/%(,:CA$,,@4%<:,GGGD)4)!-&9;$FE1'3>@@+6?3HH=%0,
@r2660
CGGCAGTGNGCGGCTGGTCAGNACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGNGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCATGGGGGCAGCAGGG
+
'E=*8H/35H8(+<!$4F-B<.8'86*,0<B,9H#)2#-C3,5D#GB44E>47=F+A4;*(%;.*<1!;C/.552H8-1D6;9%5=4("F7":4&0CD&;"2B?>:+:$!>,2:6>+E@(
@r2661
TNATNACNCTGCNAACCNGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTCCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGGATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCGTGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATNCTCGGCAAACTCTTTCCATNCCGCTTCNACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGNTAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTNCCNGATCNTCTGCNCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTTCACTCGGTG
+
&!")!'##((('"&*'*!+%+(!&+*)!&"***)+!+'!#++($!'''#*(#"'#(#+("$)%'+*"$#&"$)*$"+&&)+#*")%'(""!%&&&*##+))!($#%**&*$!)#(%&*!(+*')+''+'*!**'&)+')#++'$$)($&&!%(&)"*%*!#"%"*(*!"%#')*$'')"($+#)*''&"$'!(%%**+!&&!'!)"+)((###$)(+!%)!"*%)!&"$+#*($##!'$+!%&'"#'!((+'""+""$*!$%'%%*)(*!()(''!''''*$#")!'#*!$"!%**'%(%&!%#$%)+(()$&'&&#'+*%#+$!'#(!$)&&$*("))#)+)*'+'!!%#$#&%$"(&&'('(%&)#&&#+#"$##($#+"#$#)#&((($&"%!$$#*&!+#%''*"&!(+$%$($'()'#!!""&&!!%))*&&"!$((##')&%%%%$$&&($&*&&!((!#+$"&%"
@r2662
NNCGTTTATGCGCTGGCGGCGGTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCT
+
)!)'+)$&#&&%"$*$!"%"%*"("#++")#'%*"&$%)+))%$)*()'(#!"$%"
@r2663
NAGGCTNCANNNTCAGCNGNGGNGGCGNCCTCCAGCGCAG
+
!*()$"""%"$"*%$()!!#&(!#+$)*"(%&*%!#'('+
@r2664
TGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGAT
+
2*+=H3'%%$D8,-(48:*3.(2<CD8=HFB@-G>8.;0AF#C2#(0*;A$D/-,G4D$HE;=*0E,<(*;(1H
@r2665
ACCAGATACCAGCNGNCGCTCAGTTTCTGACGAAACGCCGGGAGCTGNGNGGCCAGTGCCCGGNTGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAANCCCCNTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAG
+
?='C".5HG2*6:EC1,8&/+:0281=<=%951#$!#6GE(52-:/-GB.@#.7.9CF)&8!<(&"+/0)=!%36?,>*H=?/)>H;759FC%"(,H@GC$7$G,;*89-<FG%D>-/83FCDA(C$DF((%0"$$!H/+1;8)G4'8-;,#4=E.0>/>)%8)8@*1/,4E"+)"=GD)/7$=;;,!GF.,<"'0&473708A9(:+<'+:77%/A.8HF-9&*!83D#=D**0
@r2666
NGNGTGNCTTCACGCGTGGTTTCTCAGGAGATCAGCACGGCANACGAACGGGACGGTGGTCAGGTTGTGGTG
+
''&!%&!!#+%+"((&'!#+)%!+!%)'!*$'!"*(%()#)+$!)!&&*!$%+#+""!"(+"%""%#!#'$+
@r2667
NACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATA
+
,##;#F2A=G=&"D1,@*</5.=A6B4":;B4:.B9<#B1"<->'2>0$=;>2,)<@$'7:AC:/)(%=9'D/C=<C%4D>
@r2668
TGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTNTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCC
+
C&.B:&HBG)H"+=A<"./35C&7@&)?D,?E/B,'$+%39==4.3+&,7><@4+49>/.)&%1,?'8-C=09?*='9:@$$G473D5@+@"%
@r2669
CGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGNTGGCGAATGACCAAAGAGACTCAATCAACAA
+
BH?:#H(:$D'D:D=@E8>3'0E377(F)3;?>G-G5,H?8H,=(3+E73-#25?19$H(G:32@2-*5,*(A,+9%0,/2;E5
@r2670
AAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCTTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGA
+
450%7;9154:"@*"=?0/,3E".#@)*F&50)1AD59<'1/G#3.#?=D?/BG+3&'D7::=4E*8"F$AG/8")-5F=?EA,%'>;;$&13D*0!7',A777@**:*2F-:.D2F&6<8=.HF2<%#8$)=;;#?.34#7-'82<E-%2,13?29,/>/7+?6!5F3B93G18C$+G)%6D%.8)*/(<;<DG/1<B;:D*G1F4=)*6BA@%(
@r2671
AATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCAC
+
H;#&<9474+/?*;6?.-57A=F&7AF3),.(F<<6=7B118!C%F4*-$>5(A@5''4)63;'B(<H@9;@>D4.EF0>,75F,
@r2672
GGCCAGAAGCTGCATGTGCTGGAANTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATG
+
EE3%A*98H*H;-%+",?)@;94D6B7GAG48=H'+@#A-D,5G!2?>)?F:A-.*C5ED"EC:@(6-6;$:!"!'A/<+%
@r2673
NCTNCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTNTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTG
+
##%!G=@AAC6.!=*0+H"HB6:"0&;?,@C!FE(G$@C6%HFE#A37D&BCC?H"7?0H0+B9:D48&?/2F?B$1(E/'6;H0/H#/G1E'5F4HF9!,%!%&GA-/=*,=;1:.$&&8%,<*C(.2=0+D>+>/,!?%45?#?"2EGH5#H53?)+D<+;B32(5C6/?01".DB8-77405;#605!
@r2674
CCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAAC
+
+G$,@7!7=-08,22078.,=,1!01<::A32)+@&=9"B:)+(
@r2675
GCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCC
+
C0*@3(-69)B?3.-=!969;;,$00E+&.9DH;D#CE!?0A;,/%;B2!!H5?:/0&7&@CA,3187?2A,@63,=15-<!C
@r2676
TACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGNGCTTTAGCCAGAATTTCTTTGTCGTAATCGAGTTTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCA
+
;-!;9&$<>#3G%B,.<!E"-G5*)3@E!'5+B4>*;//"AA)*B,7F>8(-GG3)"H$/<$H>-2D9CD>3A:!!CH-<7D6'1#;H;9(**4&.&:-E"7+:HH)<<.83#E?*;?H).C>(.GCE?8?7#-@B3<ACE%$1E'$(*+?G+FFC$>,-H>".@6%-3F:!5AG0>(()$6?H)H(*55&%7&B@),;$?07+BB4.<)H%1:&/="9,/:!$;A$=H
@r2677
GTNCGNGCNCACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGNAATGCTTGGAACTGAGA
+
#(%'$$*&('+")&&+*!)!))*)$*()%%&'$"")#)+'(!)#'&""'(#$*#($(""&#&%&%#"+)$*)('%+!"!
@r2678
ACTCAATCAANAACTGTTTCAGCCACTGCTTCGCAGGCNGACGTTACTGACGNGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGANGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTT
+
D/.#::<%*C26<<5/8300?"6D#+)@(A"&+-H,@.A=;'+?.3C-.9F%4G$.G&8.-6C&:<3A5E&@5C8=A:"+1:':!?0A<*:,8+(C/F2H.&(:H=+5H(-/*-".+B.?)B/&'=7"2'(13
@r2679
TTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTNTTATTTATCT
+
$7EGA,?D*,+'2=B/>6E+#G'*DEH%$>"2H.2/@4:/4-7FG:120$/&#F(;;,'@;%-GB'+=).@6D62,?'-$8C++'&B0)8-)368
@r2680
AGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTC
+
G5G>;$:&<9E@461#(0.")C?B%3..79?'-&H4'8+/<:.A7,.3#C72H"0?<(0F>$H5$<9*)',1>)6*6HE;G#=<%E>+33,)D-9A&92D..1E)(#%43<17:*$9+9G.%&1>1.6D/
@r2681
GCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAAT
+
B)A6(5%(<,G-1$(4)A-;*18%(:C6.$'%!60DG?;@0F5C=%'<E>=?*8=0=:*"=:E/";)*!GBD-&=G/3):*A73'%6>-C9<F$@98>'E
@r2682
TTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGT
+
*/3D09%):7E53&=>;+41A;!/,0&.F$.7(.?=$#6>060/C+
@r2683
CAGATAGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTNAAGGTAGAAGCCAAGCTACCTGTATTTGG
+
.*<%:?90/A434@)($"3'=",<1:$:+8EC5B5&%!=C5;87+)$+H<(=:2H!0-8)#:!&H29!AD>B.#&8A82EF1/-C"-GEH=F&DHB&6511D)6
@r2684
AGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTAGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGNCGCTGGCGTGCGTTCCACT
+
F.E/H6D:E97H>31G8'4(14&3C15,52B+@*:C8F@$893H4)99E>6@)<""6F103>5C06>E;09"BB47.8?!AE!)*6G*.@A%D44"+H>.C88B!;H64F3AH6$&&7'C9%$;#6$?2"-%DD*?!1GH@9;",:A$,C"3>8,4(#,'
@r2685
TGATAATGTNGCCCGAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGNCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTA
+
F&+G"&%-7'/C9D59>".D$9G#G7,4C,-E+$0%;.FFH-<8@:2&&:")9E.=2%8%8H!-B55)5G(.:8,.D*7%>5HG#))$5AC673%BF'.9.A)#
@r2686
AAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATA
+
A="5%C=(2+4<.3@AH&;'/.+@9B00/7E9GDF6HD0#/!>%"/
@r2687
ACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATAC
+
8>,E07$417#7#1)G**(?)94!7*8B*%4G0'/!'8*1G'#H?&C/H&H=B7B*3:<=.=B3'+>A+!)?:8&+7;>(0-#0-&6*/(+DGG"
@r2688
GTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGT
+
2G:H-6!$"D1,GG9.FC#!&4!7<://@&=/44/8&#//AA()D*!>#)240:+FB0/"6:"B;+<!HB1-443'B*E'6!,!''4;F"#9"8!@:2G
@r2689
AGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAG
+
<1&-:3F:.$'B<B&94)/932@8B39B2)$/G,=98>@F'G1&=@#)&(0B;1)0F*+(,8"%C5%.4/&*%+>"+
@r2690
TTTCCACGCTCTGATAAGCAATCAATCATCATTTCCTCATGGTTNCCACGTACAGCTCT
+
*2!+$'F&-9??F>"0!1-*1=$#A*(?&&%3,;$(-$BB7DE.&4&*4@:3%<A>4FC
@r2691
NAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATACATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCNTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGNATATATGA
+
%+"(&%%**(##!(+$+!+$')$"")$%#'#+*(+"%##'*"&&%)%(($$%'$)$"**))$!$#!!("(()(!)$%++'))(&$&&'##&!*+$$+))$)()+)+'%(+")"""%)*"'!)*$+*#""!'%'$&!$*)*)$&"(%'"&&*'%%()(!$+&$*+)++&#&*)
@r2692
NACNCGNNANNTAGATGCTTAAACCCANTATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTA
+
*&)""!#"%!$*%)$)'%'$$*%*$&$"+'$('(&%'!&!*+$&"#!#&+"$$$#!)%&))$$$#&%!
@r2693
TNTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGT
+
$$F<$'84$HD*AF4;CA77046/0.7@?+:%=E?8>>/'7,%D8<EG+*E*D&?D!)H$(6"HG&A"*B3C.8A"1<B.,)2*E#,1EA<;>;FC42,,BB!'"G!690FG?-?$@./;!+79F*"0".C0=(18(!D+$(,FD25<A6-:CF01$9@@0#(@&B
@r2694
CNCNGNNNTCNGNCCCNNGANCCCANGTGTNNCCNGNTGCNNTNNCNTGCGGNNNNNNTGTNNNNNANACCGNATNGCTTNNGGTNNNATCCNANACANCNNT
+
#$$$$""#$#$#"$!####!!$!!!!#$#$!!$$""!#!""!"$"#$$$$##"!!"""$$!"!!#!#!$$#$!#!$$!##"!$!#!!"!#"$"!!!"$!$"!#
@r2695
NTTTACCACTTTCCTGACAGTGACAGACTGCGTGTTGGCTCTGTCACAGACTAAATAGNTTGAATGATTAGCAGTTATGGNGATCAGTCAACNACCAGGG
+
$,!F7'.(43+'*((1$B?D8C)#:2>525'<<7F?>2-8GE-)1("C+;)=6+H;1&(:HEG$&.!:(AEH*DH+@'?"(CA0EH9@=039.*8.%='!
@r2696
NACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACCGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGNTTCCTTTAACTGTGGATAAACTTC
+
'$GD=A+H!H4-D6)B1H0@#H-$"?><'$50*#:*@?@BBE0!FB<A*@@6..=+".5-/-9%-=B4AG68(,"3H"3//A,BB2(#H;B9??)5/G1(<D5>A=?(=9$B;<:!($&6"H@3<3%&7/D'-)D7%E178;.$/,=5=F,E7!$C@(2D"
@r2697
GNGCCGTGATTTCTCTGCCTTCGCGAGTTTNGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTNCGGTAAATCCGGCATGTACAGGANTCATTGTCCTGCTCAAAGTCCA
+
&!%+$((!'"$'&'+$*%)'++##'#"&$!)$+"*''!*("!!*$(&&"'%""&"&"("&(('"#'$#"$(#"+%!%###"!"#&$(%&(($)+'+$"+'*&%&%''!#!$(#"+'")*%%"!!())($)%+)+*!()#%#
@r2698
AAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATNAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTTAGCGCTTATCTTTCCCTTTAGTTTTG
+
-*!<.1!',4BHCF?6,37#43=%#FB#H8H%2E>EBH5%B5D;!)3<7CDD(?!&)9>/AG"<(E?02)@4)@',%B,/9E9*6B(@0G*5C"A*!=:#(H4D(-A9.+-=6A?4#,5'4D'GFC*(@7B3C.$$C.%&F#$@,)+8!!:A?,63'22AH134C269A9)>C?0/$;006G3'F3G4
@r2699
AGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCCGTCAGGACACCCCTCTCAGCCGGGAAAATTTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGAT
+
=(?-;3>E:2%*;9;3/8?&?)=;7??:"A/:3>FD.;)$F.().6"53&$9"&>"6->1.(+@,.6E%8&.0)&C&),BB.8C1@26/2<6::58@@4?9<6$@+5<")+=G%*?@+CE74=5@B#'AFA957FF@*2"+D1*"5EB>%8+DH=/<D%">C@@@/F$0&334(*=)C!D@":&+%D*@F3/07:C0F+:1E*/@6504110=H#((%6F4#:56'2%DC'4@0(975>9CA
@r2700
TCAGCGGGCCANCATGAATGCGATGGGCAGCGANTACATCCGTNAGGT
+
@8$H'<AE=,-E.D3>',"?/#!CB/3+-D7"(-72GF0F)F)'C'@$
@r2701
ACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGA
+
3:9"(C50E;:8B&44,",F8!*->3,2&9$%GB>2.15/
@r2702
TGCTGAACTGTCAGNCTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAA
+
5C9=%FFA<3E/4'9@""915E&=*,/*FD#);8466?#92A82C=(E'H,69B?<D0-B?,D/BD#.?@*?"3$-)8?"=&B:#9G6,F2'@+">D=@G=')C>+4.>8>;E"!+5F+#:)
@r2703
TGGCTGTATCTGAACGCGCTCTCCACTGCTTAATGANATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAANAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGA
+
#34974--/!1.7/60)G8)&(-=53+:.33E'48.DAGG20?F&<:@CDE7.3H1B@+.DF))C8B:9,4D2<4'G?'(CCAB=-:<&6:><(@:G*/$E'#HC,0&)%G()(@&/-"-#8"?983H,B*9F)*8>#?18A95.3*HB7:0)HA,.A>?9FAB62&&&9$@0,=#&/.3('E(=/577CA,;>"(.)&/7H!8FB3.9("H?-
@r2704
TATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACNGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACG
+
H=5./%=C%+3(28"?!0)"$2:':!:3&&HD(3$7>/;+"8C.=<&6@96/F;&%H00>!'AC1803,&DB1@@")+679H32F3&0&E4A&4E5HB!-*??/3:68H86*/2H7@.;9C9782@$07865!C2DA/;10%9:,&H6D8@F!=9=GH:EC49*"A$G)#1$$H@<;%7D08"!1$71DE$CHD&
@r2705
AAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTCACGAGATCGTGCCGGAGTTCAT
+
>3-1)@&0,=C+(E!;G=#@:C+F(B;D:H*E9%06HF60,5#%6/+EHDE:7(CD=5>B"H@#8(/G&:!-7,1)91E741#&B8:-<1*,@.+0+6/-*?7"H=7CE.H@B6'*@</6='
@r2706
AAACGTGCAGAAGATATAGCTTCAGCTGTCGCGTTTGAGGATGCGGACACAACGAGAAAGGGGA
+
62"3,)!0-5B+21-!2')*,"'B4<.#0,=713/4$D"+0:37%E<"*%"D/!,-*6!/DGF"
@r2707
AGAAGCGTTTCAAGTACTAANAAGCCGATAGATAGCCACGG
+
:/+G$90#9?E)(D>%?7#DG:$7C"DH*E#$@/H.H+871
@r2708
CTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGC
+
+%""**"&)#$*'!++&(#)&"('%"))(#%++%'"'%++%'(#'"$$'*$+#(
@r2709
CACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTAACTGCTGCGGTATATCGCTGCCGGGCT
+
H<=&-B)$)%;()&/F?+)13.D'44*@#-0"A;,F;"H>E:(#63:#.!A:E8H6%D05!,5',@855!01D3#%-#%1%>.4/38F@$!78=3($+#1-4*4B%##(G#"F2FG*?&)D)/%*@<)0@6<9/)C>F-5,(7%CG,#!'63!4$'B0F<>!-E.9A&=2%9'3*+>#H1>6$A96@8>&E5,AA?H%>.%8:864<5H1>,98>,("24<;#H63<5+(?>1FHD+="0?<))2.!85.<+/)9(79
@r2710
GAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTNCGGTGCCTGCATCTGCGCCACACCACCGAGCACCATACTNGCACCGAGAGAAAA
+
<@"?4-23"/9-H>$*.0F3$3#'H4+<7&0B:4DH),;%3@D?$34F6#>:$&EF;,@<56=19%?G;)G<-)D?"<HA1(8)2/H&':*!D>=.;'F422-='151H8781!071#C6C'5E'-(E7';9"4:39$D.-/:#<;="/19FAH6C5
@r2711
GATACGTCGNAGTGACCAACTGCGGAATCGGTAGTAAGCGCCGCCTCTTT
+
+&$'&"%+*)!'+%)###!))+&$%%&'(*%")&%+(')$%*)&%'''&$
@r2712
NGCAGCGATAAACCGCAGCAGTGACTGCTCAANCNCGGAGTAGCCGTTATCCATATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTTCTTTTGCGCCTCCCCGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGNAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCTGTAAAACACATT
+
#?7B2>*:EF8G6?)E2+.1=4D1@/-=.?$0D;C-!4(02HC$59/%161"/21-.H7+?6>@CBF?!7:7;G7/*.9<:4,#!-6%/*A@5=;0120#42HF)F2D.-,<D&>G)2F@@;."1C7,A"<H@,+=<9F'C?9!@"52?=G8C>>F93@?3/=G@<<3=8(,'8C.*=<5,B36$+@,*G&A=721%<*&8+7FDD/*+A4G?07!@>1D@;4C:1-==G35,;:+/3+@14?$;*,"6E'*;&6,9#@;31/0HG@#''%G"4EH53,@%*;8?27)B0,:BF:."E"*H%*"<,DA=E)8,:48#=/%/-//D1D1,H<3F<F77&%DC#-(*!#0
@r2713
NTACGGTAATCCATTGTANTGCCGGACCACCGACTGTGAGCCACTCCGTCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAGACGTANCCTCCCC
+
"6+7ED-(;=:E'$>9)&C;*"&3@9-GG(/313?1'@5/3G3D2;241HC:GG+E%+C*2*!:@G?'5)42?$@@'2/:D<"AE0,#'3,F5;'%+6"#>;,7A-714G&4.46E;'2B/:">C>*BEF7&F,*#(G=;B)H?C1391=G!
@r2714
TGNNTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGC
+
"&"&+$&%++!+%'%)((#%)&%!&%$'%(&#+#&%!$#'$)%!$'"'
@r2715
TCAGTGTTGATCAGATTAACTTGGCTGACGCCGCCTTGCCCTCGTC
+
DB<B78(-8=G-&@#'*69:7@5G/E))%';'H2H:B.G%&/(@**
@r2716
TTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCC
+
D4A<"F,(B5/$BA+A:6,4?/.)A?!73>6*D0(G:(CF.20E205C3'''<7#?)-D19(GC)H$B4/@?>%5<6,F!"7-0'@%',4G'#60;
@r2717
GCAGACCTCTCTGCCNGNGATGGTTGGAGNTCCAGACGATACGTCGAAGTGACCAACTGCGNAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCCAATTAACCC
+
(&(*+!$*)$)"!)**(&)++&&%$*$$"**$("'"$$#!(#%'+!$&+&!!")'##!'$((!"+!)$+!%($(++&*#&$(")!'($'+&#+!*+&)(&(#"$+()''%&$*'*")')
@r2718
CTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGA
+
(,F+.:!#(#C!%C+*7C%HH.,;!D";1<+.2=-@H+)9H-A,26$%4:A34G3/)1<+.BE0G;0G/$
@r2719
GNAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCNGTAAATCNCATGACACAGACAGAATCAGCGATTCTGGCTAGCNCGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCG
+
?48E#>?A'1,("=/:-'&F?@#7GBC:7@#AH<2=>9?68*CDAH'7E=/H@<'0@+=H,<>*8%42.4&)9<G:B!1;4G92A/7"D3%,>=/215.?'8*3G%&!4C$A$312:+!#AH#29A45D8.'<G,;>.9+?,,F)6F:B<7<0<7)=5'H(<,6'1'":@,H
@r2720
NTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGN
+
"+&+!(*$*(!###&$'#("**"%&"%&&%'+%$+'!$"&"+()%(%#('("**!*#''%"*%)&"$$#"*%"''&**&&*($$*!"'#
@r2721
GTCTCACGGGCAACCTGTGAAGCCGACTGGGATATCGCAGATGAAG
+
D(C4!,7C(C@'?B<ED1D='E7'5C=/'5=/8D%;1#@@.2"@'A
@r2722
AGTTCATCNAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCNGGCTGAGGAGATAAATAAT
+
BH@%+6-H7+!20,44H?+HF)=+'9)C283?#E.$.2$+.!%(<$:::D""4(:;C/H%%1&*!G;#-?B2=B+)./<F>&031<F:B;:B-+@$50GA%@!7A=7<A@9H&D!7>%6E9C4>>$#0!?3G!8+6/34@D0?/H)<'+,H6!"1'."=:E8:%(H@'1'&E;7*5H7"7E668?()1?A-D?$.)9>:0!.9B7
@r2723
CTCNGCAATTACACGCAAGAAAAAACCGCCATCAGGCGGCTTGGTGTTCTTTCAGTTCTTCAATTCTAATATTGGTTA
+
&164?C!$>$$F:/1%198%&1!H)7,<6/=:A105G%(+F.%B")63$$B'%<893#+&C,>8*260"GF8!AA00G
@r2724
AGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGG
+
.@<G*?&0/@C'CFB)5?*=90C*B)C1-F"?A72#!G7$5=?HC<FC?#'10C/7G)CB@:<1?>BH/3(H"#;F;":,<338!!>4?&GG-?=$+A,HF1E/A0,3,!%<-A!<<.:5):/3$>2*-)%1-G;08*72.036<H;(76:.0$556!?2#'0,4=7GE,
@r2725
TAGTNNNCCGCCCAGCTCTGAGCCTCANGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAGTAGCTGTGAAAATATCGCNCGCGAAATNCCGGGCTGATTAGGAAAACAGGA
+
)'*'!$%")$''+%$*%$++*'+)$!'"!#('$)"*)%&'$+"+&!!$$(+(!"")"+*))!#+$)'&))''!'#!&(&#'')%#("*))%#&$)&)'*!"+('*'*&!!"*'!($!+()('(
@r2726
CGAAAACCACATCGTCGTTTGATTANGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGANGAATAACAGGGGGGCTCATGCTC
+
64$85F3489$"D(";:!&-6.F/C6@&*B-$4:.9$B1F+"C;?8G2&&!?5BE371F(H6')<;(E5-H@6'/$HBFDF7#0<44=*DAE=
@r2727
TCAGTGGTGGTGCNCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGANGAGCAGAAACNGAAAGATAAACGTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTNGATTAA
+
>92)5D$835%:?6--'H(>?,0"556H/):G<1>5D+3-A=$5&?->:.G5E)@)4'12%/@6&-'C3F#C+*$#3##9D2!(.'6&(/FCGG/$:"4-"<7&"$5):$&E"<&<#4:2H:,D0:.:&1=D,"'B#D6H,F%:9A6@='02B>",:*-:=0DF'/5?F%;.A'
@r2728
CNGTCACCCAGCCACCGTTACNTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACNCCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGNCATATTTCACTTCCGTACCCAGCACCGTCNCGGAGCCGGAGGATTCAAANCCCTCCTGCGGAGTNTTCTCCTGCT
+
%%%"6A,4!#<")0D:DH,:?2+2,)&=8%%=)D5546G3$&GF2+E=&D8$*6#;.?)(:(,83!)4.*&97-/.<:;%69-%+>.15+<,H1D?@B&@1/8.-7BG1)?590A753#$%5<*:F)2%E&.!+,!3%!:=!A&E,1=6:1<?C3=@02/4C.>A6(0!G,7&$.*.-C/?:%H+<3D61=9A;!CF:H9>@"/F:@+&H/<'/#;+"37H/E1$!5($A%9E*
@r2729
AGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGAC
+
H2""4)11HA7*3.>?%++9=?';7=&&1$,>$;9G=-"H0,@08A>H)(=#+:G056-7-4@'A#@6$"&->D1(.+9*D$95!@5D5:/1$;%AC*B906B'=275G@A+!%3;D>>?.A<6D4$-4D0@-$>>21"C:6>$<65/G#+4HD>:+*$3.C<6'-E!9:,05/A-=)/,6=A="+56;CD@CB#;,A7!
@r2730
TATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGT
+
7!@5FC%4:&4!<(0?$;.//--8,'31*6=<6@2:0*+;B52$<1H.1*/:*H#8()>$8<H'C:5-&8!1&*-)>3&?:141#8;4B>!#.<)+'#H,B0.?7FB@GF0$4
@r2731
ATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAAT
+
>F'#$,29,)=-29'$7F&/)B%723D>GB';F5%5("(/-),-25A
@r2732
ATNNCNNNGACAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCCTTATTCATTTTGTCGCTCCATGCGC
+
(*!))!&$"%*+*!#$%$"!%+(!!%+!%!)'()+((#+(!!(*#%%#&')"+''!!$#%!(#*!$!'&$#)')!#)(#$(&"#+"(")"()#*$#!*(+#*!+*%((*%*+$&'&*#
@r2733
ATGCGCGGGTTGTCCTTTCGANCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGGAAGATGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTA
+
6.%E!<;-).1<:+/="6<9C?207DE,D7*,#9@G22!:9$3H:A65"5'<A<)H=08'E-F6'!+/A8=-;.D;6$G+:=/D7'D2,<2!EHD>F5..G>/$*9-(&BG'(C
@r2734
NTGACANTCCTTTCCCGATTAAAAAATCTGTCAGATNGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCA
+
"*)()+++(#%%!)$)(*$*'**!$!$!!%*%+"(%()"#)#*$(&*&%"*$)++!+#*+!$"&'($)#%"#*+
@r2735
GGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGT
+
E%8+0C(#";"-@>F$+A#7C1$B87B!$HA6&<:CB@"B%
@r2736
CAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATG
+
9'9>#!?D.#*%2B'6@!35444+<'>0:@,/;7&/G0!&,D>$F7<9!0GG-H&&:(.'A>=E7F;61C/9?BD0>.$"!):/,CF3/
@r2737
GCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAAT
+
ADGBA-*->/5,=?'%*0/<--30,%3-4G1%/-*<2C3-85>GB=2'GEG8!>"C
@r2738
ATAACATATTTTTTATCTTTGCTCACCAGTTCGATGTTTAATC
+
2>B:3"#7/;5#,"2!E-5H"81&2:(:9&5?:6-.)#@="B&
@r2739
AGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGNATTGCCGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACNCCGCATCT
+
A6*C8!A=D=&%A7$&FH,6!;;;4C(1:4/F/:>+,F40(2D=6@5H>7$9"%?%4(1'&2H,152&-&?E-.,$?,)<#>!!&G(%)%H?E3)B+!2;F!"&7$+-H0=-=*,>!8:(G1,D/*18*.=?!6!..1$7
@r2740
GCGGCCTGAATGGCNGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACA
+
1?2B;:4*169"E.03>B2G<$/@A@3>C,7)3:?031(*16BA3'85:4:29$&3G18<%G:$"1D)28.#')!HD$%<:
@r2741
GATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATATGCGGCCTTACG
+
/4690%#'('F?(1$08'9BHB/96'.3D6#-18144%H"+9:'>(7+1E57?GG6&))E
@r2742
NATGTTATTGAATTCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTG
+
$.A)</,--7F!8!)5$2$<H:'2.<&-&+?,<8,&;(<3D$-A0$6->9'+!%-!D=:A
@r2743
GCAAGCTTGGCTGTATNGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAA
+
A'E",(E;92GFEB08C<*2H>;A>;3B'@D67#1>>H=-H+?7A6H1(@9?5:57)$C.C7,(%G<#1D/#7H(1'AH(96
@r2744
CNAATCGTCNGGAGCTCAAACCNTCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAANCAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACANGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGANGC
+
)')$)&($*#)*'$(#*#*)*%#$+$&%(&!"$#(!'*#&%!#))'(#(+$#'&#+%"')')((*&%%&&&#*&!!+&(+"+%)&+#$')$!&#%'''+"'%"#%&(*)(+$%!*$!%"%#%#(+"#!'!%()$#'!**"&!$)%"*(**&*(+"'+%+""%$+(#$"+#&#''$(*'%))%++)'('"(&!%%)*%%"!!*"$$+%%$%$&'))*
@r2745
NCGTCTTAGCCACCGGATATCCCACANGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGNTTCGTTGGAAGGTATTTGCAGTNTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCG
+
&%&&=>$5#:%+.C.F<7=%1?@/%="1,9?/<?0,*9D01BA8>(A2(&F&C'##2$;9:/,#$!/,1=*C'(BD:<<D!0==F8,*)"*0?2C+/74C>*A30@9@-@;.@(;DG5#6'9.!9#$?E-'+/C?&+EB43?<ABH0.<A7)8<!>19
@r2746
ANGTTGGCATTATAAAAAAGCATTGCTTATCAATCTGTTGCAACGAACANGTCACTATCTGTCAAAATAAAATCATT
+
+/;'C$&:4F/D5%H*D*&7?3@,,@'/)A!,'+5,6=<=B50H(F#/,7(.E+7$&-9$=E,+@$+1E:19<"*,#
@r2747
TACGGTGATGGTGTGTCGGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCG
+
%D":.B"<.&6?A?135E$3H>44;,H"E4"H;"D<$'#H5"@?4<*8"0"90=*
@r2748
ATCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATAGCTCTCCAGCGGCGTCTGCAGCCGTTCGTAA
+
&+(D;"9!*#5A%#HED>.0+EE4423/!#D4275(D:%B.?H"7)1@1F%-58F2382G/=+6;$%;<7@GB
@r2749
ATGGCAAGGTCGCTGGCTGGATGCAGAAAGCTNGAAGTGTGTG
+
#+%!!)'('+)%"')"#!+(''!$&(##(#%("(*""$#*))*
@r2750
CCTAAAAATATCACTNCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGC
+
.A(:'@5GA6<2#>/$3=-$80H!,$0$5,5>2&C?;:E0H'*%1*#&11=E0
@r2751
GAAACGCACCAGAAATAAACCCAAGNCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAA
+
86':(1B/2-)>:G:45<<,$CH;97)AH8':=?3653B:-0=<,,<G.H28<%-$,C7-$@+/&7$3#.F-71F!&25):;;(@9:-&!7G(484*5D=B>=4&H(:06?18?"E
@r2752
GCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGANGATGCAGCCTGTCCGGCGGACGTGCTGG
+
@)?621$;<>A6)$3#:%DC(0(%-!*4G&7<'50CC)#C(!11FH4+2H!39!D@8+,&FE=?D409F1
@r2753
TATGCTGCGCTTGCNGGCATCCTTNAATAGCCCACGCCTTTGCATCTNCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGNCGTCGCGGCACTACG
+
D67;A*#&A=>A.:A/;'&'F8!;D.D6:5F((&<6+(<)=BE&*CB)5#/8=;7/@C5'1*';>)3)F#35'%+($)(:E!,9''259B3EF%+/A:?<C1'@)<=H)1(%>8,@7-%'&D%83F&-7G29@F5E6+H';"(!D8%?5$'>B>04B/
@r2754
CTGAGCCCACCGTGTTCACCNCCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTG
+
5.15?G3*-1:-0$+!F%C7G'=%C-*+(22!?.&ECE1(*9/&HF=&E2'B#%#2#A1CA$
@r2755
AAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCAT
+
G@9E*?0:*0F*>H06-'9(E*=70H;1%5(<E$2:H+=7.)*5E%%:(AECE<
@r2756
NCGACCAAATCGTTGTAAATCCCCGTNAAGGCAGATGCGCNCCATGCCCGGTGACGCCNGAGGGAGTGTGTGCGTCGCTGCCATTTGTCG
+
0=9+9HG%"@=#5EF<$-2=:")5E)G.*/4&+/%$,7#)64?1!@+2#8=EFA(2G@1!!8C,('H-%;%54G01*=H@<.G$--:<*H
@r2757
GNATTTCTCCTGTGCAGACANCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTNCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTNTCCAGCGTCCGGAGTTCT
+
'"&##$*+'!&*&++*!"+!&&)$##*#(('%)((%+#&$)(!(%!&')&%%+*"'*!*#$+))"")()&"('+$*)'%!$!!'#(&*$')+$+""!&+&*"+)")%#&""$)#(%*%)*&#!*(%(!&$!!*!*$"%*$"(
@r2758
ACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTT
+
H87$GGEB;1/=4G%:%&D8(0?DF5="B<4;-'D6<!#(#40#":($;=B3-6'7##$E,&5<$1)7G/(4:%41F,FH$H"A35%85@#H-=
@r2759
TTANAAAANCTACTGNCNNGAACNNNTGNAANNNTTGGNNNAGNNAAAGCATATATTCCGCCTCNTACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGNTAT
+
'('"(")*&()($)'$*""))*&$*'')$#!%##*'(%&!"'%"""$+")$!+#'"&'()$%%$&))"&($)"&*$$(&!)&'##%%!*$(*+"')'&"&#)(&$$*&%(
@r2760
CACTACCACAACGAGCGAATTAACNCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATG
+
1$=2*6D'=2""#?"!#.;B5D57<6-3F+?$!,$.2552<5GD?2)/D%.>G%*5B=>298*D?2C@/6,%&&
@r2761
CTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGACCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGA
+
=)7897D0B+32A(48%<4E%G,;B0.27)7?%F)B%6A(C,4056C51)H@BD,69<?D931>$46=B1>/5B$$H$"$1<*B/>=+!A-+&7=27>2/#A+#.93F)$104/E:1&6/<%E7A/E6,C!-(22%!-HB/0(AA@/F',E'4@9>,!.)7<>3'97'8>9:H;:-DHC$0,6)'B:D?HA,+"+"$'20$E0*(34+H'E2/"%8/9+11(E*/8C3@:!<8E&&-/*BFE"!?9"D4&D"B0+D5D1$CG246G3=7!1)6CB+%4(!&B=69@-0H=D#++5@B
@r2762
CTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGA
+
=!&G-:D(>D,D;<3(+*;7;#)+4&A*6>=:0)$3'!?G*B8.-!+!C;-A3+15FH.:&>5/,8@=*86A,#:<
@r2763
AAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCNAGCTGGGTAATGCGCGGGTTGTC
+
+"+!#'&!(+"!%(('"$#**$"!!+%(+(#!'++"!'"$%&!%+'!%$)(!%##'($+&%
@r2764
CTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAACGCCGTACTGGTTGGCAACGATCA
+
-6"B-GB$1?85=,D4)%CC!5D$>*@%8,?<:C&F"38D'(.+?+H&BC%A-2!;GH</8'A5%
@r2765
TATTTGCAAATCGAATGGTTGTTGCTTCCANCNTGCGAGGNTATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATA
+
+:4>;'%'":3<+,+D--..0$G9&*.,*1?*@4$,;-#,/.;$(,=&%&D"'7-#=?:9=$-9H!2')%,>+D%&?=
@r2766
NCTTGNCGNGCCNTGNTNGCCGCGTNGCCTGATTTATGCTGG
+
$#)"%!#*$(*'$#$"(#+#&)+($!!*+%!#%")(&'%*')
@r2767
NCCTCGTATCACATGGAAGGTTCTACCAATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGNCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACAT
+
%*=(4#+'$>%0HH>($5H!.H947=9B;%1:29'6%?C3&;GE41B4-$=C;)3+).;5/-3!A+?:9<+#HF:9?1#((56@:@18(??"%-0';7>*H@";?F?C/'>*H$&2-/!%A/'G#<A98C.4./0*'<E$/>#%%3G/H=;'8C2;$/&$=-#.7;*.#<F%8@'8G#$C=BF=9()-.&*FC0+0F#G-2!51>2$/(&2=;;H;6);6E5=;80H)<E,0A@/@?9%!A/;<*@G%3F7,(#(>D5(>1G<90(:F$)8;@!3%D#5H5;!/'*"=)D
@r2768
ATTGAGCGTGCAGCCAGTGAATCCCAGCATTTTATGCGTTTTCATGTTGCCTGC
+
&&5-"6-3;?./$#;*C(G@<=CH-#)H@?"?C)7H=;@(./2'1--9.;F(>*
@r2769
TACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAAC
+
;-3H??1&:$&"'D8)3C8'9<D2G21@<;+#;H.DD+1&83*/E+@,+G3B-37!'
@r2770
TGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGA
+
8:)@B88EE;<8%*4;54.1?@/7":18!-'4"=*B!6CA
@r2771
AGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGC
+
"'<>(">"81"E"90,5)A28;6<564@E2:;E,1&D:/F)#CH7>.FCHG-5;;;:$(A8&-A3#6>6-@2B
@r2772
CCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATNTCTCGCTGTAGGGGTACACGAGAANCACNGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCA
+
G?:6:612E655DGAG.%)!%3F3;F$9/)E&#?&6B+3D%"<,$A%")9!0-%G-&)<FA<+,2,1BD4!7/&+6+F/632(8$$C8.%7:.F>E&)C@2#3<:<H,F.43$=+?H,$-,.@+(;E)G(C<2(,4F%$'-??9-C@>).9D)5036#"".,,2&EAB1%-+F@@/B-552C*"0B?'!..9:D#G-"56/9EG',95ACE='B.8!F:"<&:.6>+=,6$HC5<FC52.D:=1A*%'#&%6(9>5/>9&C'&8(7!-D=.C!>?+1@.7)9EH(3'#>:3**>C>!!BH",?/")A?%D/$3$(.+9@
@r2773
TGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGANTGAGGCCGACCGGCGGCTGCAGGTGCA
+
B?#<#CE8;<4@D5%=23(*,@9127><>F<G4C@4!8/*(%D-2"DH(;!H-4:G?6+H/51+;:6*<8<6ED-H""(49&C+!.'H1,1E%9G>(1EF6,>-3'&(/F3.H=,
@r2774
GCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCAC
+
/-!F81).@1+>(5"*C&,>%!G>0A-!H?4A&77(>8@%75/CAEH:0#,)<-;%B@:+79/$'$"9;#64,9@E$84/:<"G6<:&%<&!"0<-C;#-(GF=&.5G-%+439>5##;0D<9@;D&D.D*.84#035&9!67CC
@r2775
ATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACAGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGNGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACCA
+
6FA.8*=D+B+6G,D!=@02H#7$0!0BE)'G;7<(#22236F)*<:3$-"!=C@F;H<6"797H*"<@&)3%C'G=7!F8!)9??G)#3F3$A&=45?H!E'9CA?!H3A6192)5-CF07A;08+D+GDA2%G5=A20;9,H.(*A?,52E3H')*+%H9(/C4$37"??6,#0A65%&"0H#=51>'1<8>/39?:?$D.%E>?>
@r2776
TAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGC
+
<(178$(38>B/>=>:16H*?*;=':D=;/?9"44294G63%"&
@r2777
GCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTG
+
4(>C6*++.+1!?%@4B"%43&;%&@A@BA;57;;E62!75")7D'E.3(#G#E5H"?,,F34",D.-2/*@1B,6D;!2)C
@r2778
GTNANTAAGNNCANNNTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAAC
+
*###')''$$!(("$+)%)("+))!%!)'*%+*"!*)()%#!#$$*&"%&*+*((*!!&%*+!$%+$!"!(!&%$('+#())%#&$+!+
@r2779
CGCCACTGTCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTTCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGAATTTGTAAAAACA
+
6HCA9$.;'5..1/.<%)=%59.B:A;/E#H1#5'1*"!?7+#,(;7E9H>@,!8"9%C'%4%4<9"97+2'9=!D(C7"F.<(1%3/)5>-><*"A'.3/H29:4)$9-$=D$@94)+#!-78/C+E
@r2780
GGCAGCGCGNGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAA
+
#F*&(5,?E8(-A<#6<&&>74-/.'94/00(/%1EH>B<>*(G<A7:)!62?D8#HD3)$5<A*-$7>F.CAF'?'$!.B.&F*;";/D-2??;GA#(=&F124$B=BBF='HC%+
@r2781
TGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGG
+
355(2'6,$7>EE%1BG5AB"5<6,"'89&1B3(0<7?;E1+%'7(HD
@r2782
GANNATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTTTCCATTGGTTTATTCCACCCATAGGTTTTACGCA
+
'&,,)6B>%C'.,/1)#&E"F7CA9'*($5$!600B;>-9%+!=CD9-,-17$/7G@:F7.(/3><:42HD+&CAH7,<7#8-F:A3/"D<2+A!:8.#@($8(/E9%;*6-,B--C"GB@D&+?=
@r2783
GNTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTA
+
*!4%27'=(;"+!5,+FH-08#?677:=C)484+1.H.!A<3AE3$F<1#.C:0:);<,7C$92C..D.E"%
@r2784
GATGAGCGACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGNTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGANATACCGTGGCGTGGCAAAGCTTGAAG
+
<6($<*(E=74&52/'*B(A9H%84&<AC(FH-7&D?37AF#.D/*&1;464<C:%;#(=&2B)CB0/6331)-(?<=G8+5-&71/84FB+1>3.+*6:>-0:,>D)B"5&<40A7,E>8EF2(H''+A-8,970@,(F;/84>6<9:!-2?96BE%&$FG<BF3!6<CB91%#%;D)F/%%..3F7!5D!;;<=94@;3*?90,"<?2!3"!<&#G
@r2785
TGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTTANCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCA
+
/$)7@:/D(2=7#<,G+DB:F$.)F>@CH2DG;,$''E5)F+AC7,$>73<&:'-D6<@@)5G<<G#.#9#2@5/HB$5:40>7&/%&C=49@A42.,$,8F4?!,GB("+-!C1D.A,!-)5+5)!>!E2-B27'B./+!
@r2786
CGGCAAACTCTTTCCATGCCGCTTCAACNTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATNTGATCCTGATGCAGCTGG
+
3-(D#E57>C:2.+47F0'==3B8BB=/;<6B=42.7B9(-C<=?47!%%2A7/)&#=9&-H?+9H<!)$:*7A':D%9C'+3)%5!8/+=22;H.AB&<#C6?&<'/=@A<0(BD'4FFH!A35.F5;863B/C5E
@r2787
TCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATGTCCCGCATATTGCCA
+
H*G49'%".%124G5B%FA"5@<+F&4&DE;$+=H8#26.#D%H.+G=?#:(>#4=)B2(%8$:.@$G<-9,,:@GD:>HAH<24()<74265:1;4H@626408/#2@9!5.1."EC<*:)7+.<G.):"58$>#>2(C#G+81/2/7E2$,B9@*B?"G5*#FA%@AF$+8>&'EG4.*'H>4="2.,::3,>*<&A<(94&D$6:0>*9*0225?2;7D!0*'=CB%*<D6E/!*:3;<)F=')B:!)G4G<A
@r2788
TGAAGCCCAGATATTGCTGCTACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTA
+
*7?5"DF">;2(6!DG(H3A"12%2:!D*DB(?3<(.7*$"D2+'1F$2#;D$/@0*4;&"51>@
@r2789
GTCCATCCGGGACTGCAGTNTCTCCCGGACGTNATCCGGAAGATGGCTNTNGGGGTTGCCATCCACCTTATGGCTGCCGCAGTAAA
+
&+*#$"$$(*#%('#('%%#'"$*+'$$"(%"+(%&'*'!!+&&(*+)"+)##'''&$"!$'#***"$+#"(&+&*(+')$)$)"$
@r2790
TGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGCTTATTCTTGTTCTCTGGTCAAATTATGTAGTTGGAAAACAAGGATGCATA
+
1?G68(H8E,#(A<=B(8C%5BB&@A)F*CEF%7@H-5!%<BCD%H-FA732BBE2H1C(07G.<D("DF6;=@8-?*),*=/;>/*6G./AE!"#69%
@r2791
TGNGGGCNCCCNTACGTCCCNGTATGTCNGGGCTGATTAGGTGNGNNAGCTGCGGCGTGGAGACACGCNGACCATCGGTGNGGAAAATTTGTGGGTAGATCGGGTTTCGCCGGATGATG
+
(&")%')$*'$#(#'''#*)")"!*&&%((*$")$'*!)%*&)#)&"'+'*#+$%"#$))!(%"!)##!'')!#!*"*'(%%&$"&$%("#%#!&&"+*+"($+&#+*#!))!&+&$#+
@r2792
NNNTAGGTNNCATNTTTNNNGNTGNNTGNATNAGGTCGAGTACNTAAANGNANNTNNTNTNNCGNANCNNCNCNNANNNNGNANNNANNAACNAGACGGGNATACNGACGCGCATNNTAGGTNNAGTTNNNGANCNN
+
#!#"#$$"#""$$!!!$"!!###"!!"###$!!$$#""""!#$$!!"$#!"##"$""##!!""$!#!#""#$"$!!#!!!#"##$!"!"$"$#$$!$""""$"##"$#!"!#$"$!#$#!#!#!!##"$#!#$!$""
@r2793
CTCAGCGCCTCTGAACAAGGTCACCAATGCTCAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATTAAAAGTGATATACTGGAATGTTTTAAAAGGCAGG
+
*?H<2%G)E/2+<$8&>.B+;%@?,4)55130>7/FFB>0-8A0,(C)!6;,H+3=EC./'2!=@%4'4+-H$C*FHH"98%>68FGB%BE>>">1:B+8$-=E
@r2794
CATGAGCCCCCNTGTTACTCGTCGATTTGGTGCCGTAATNGAAACTG
+
A,0#B61+7-)2H&F@<)*=@&6748(.EGGDA5'(7A?A3279&0&
@r2795
TANAAGATTACTGCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTNCTGAAGATATTAAAGAGCGTCTAAAACTGGNAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTCGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACG
+
#$+)&*!%'+'))%'!!%&)'&+)$&*)')&%)"(&%&%*%"!')$%#"&)(+($%""'"('+&!)"##++*'$'$+&&$%+*(*%)"%#$'&'+%#*)%($*'*""%)#"$+*!%$+'++"##)*&"+)$#&"%$*&#(!'(*'&$$(!!&&)'(""$+"!(*'!)%)!$!#)+!
@r2796
GCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGNCATTGTTTCTCTGTGGTGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGAC
+
#(.=*94E5@%"!*D&!:2@15*,!*CE$96?*::9:7"-C<?+3H.:8<*6:/3%75=;H<.+',F?GCB.6EF')BG".-9HE8@(.@97-GE"2;4,AFG'HD.-C48-GAEC$(%+/63;)A6''(;D(24?="<A:!;%45$<%GAFD3;;$
@r2797
GGGATGCTTCTTCCCGGCACCATGCACCAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGTGCATTCCTGCGTTAACCTGTTCCATCGTAGTGATCCCGTTTTCCCGAAAAGCCAGAACCCC
+
$+&+**+*#"+$(+!)$"$%)!(!*'#*$*(*+$(("&)+"!+)!'*("#&"$$'%+!&)*(*%*'*+)($"''&%*!*)''+&+%#*'%%#$)*#$+#'##%$!"**)("+(*#"%+$+&*'#!$%$%'**!#(&#*(
@r2798
TNNGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAG
+
%'"#?H!68)E55*57(#B(%H,E)8<>?25+A(#-26#8C??@4;H9))0%CCG7<-57+E6B9A=21G1)#B$B$1%CG./E,)"2"
@r2799
GAAAATGATCTGTATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTC
+
,%>+.<33B-$A8*.%4=D:@'$."1(7)?&?1,3)?!*!.42<G/C9=,$@D:?8-E2D3F",?EB93$G.(3*&A.9G,<>;GAC!!#*&E9@&'731:C3=A@;.F=*-B/-C="H=&GH3
@r2800
GTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGNACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTAT
+
11&&EF-4D?$04+%21%C*A+(BH!GH3&6)5-/0*21FB9H:C/G@,9:B*;?3)=1($>;%EH;F);>0=6).::&H:EG"4"/E)-86''5C
@r2801
TNTNNNNAANGGCNNTNGCNAAAANCTTNTTGNNCNNGNCCNAAAANGNTGNTATNNT
+
##!$#$!"#"$!"!!#!$!"$$$#$#!!!#$#$"$!$!#"$$$$"##"!"#!!!!#!$
@r2802
CGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAG
+
1E&0A(1>"<E$6,-">$*>&+;:"":"-7'E$*<:H#@7A;
@r2803
CTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCTAAACCTTACAGAAGAGCAATCTAAGGTTTTGTGCNCAGCCCTTAATGAAGGCAGGAAGNATGTGGTTAC
+
:'=435'*B,6)>%E?#%EEGC<8D;5+0<"1#*7)$(":!A8G(640(."3)/&)+7<EG>.&''#*:7.!F-*,**50"9!>F(!C+;6%*E;E,9HC;>:8%6GD,EGG(AG#17;/A;&A'>:2#'.E&')/C0>>5:FA5%9@23,
@r2804
NCNANGAGTTTCTTTGAGTAATCACTTCACTNAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGNTCTGTGTTTGTCTTC
+
""))&+$&#&+(+(%)'%$&#))$$%##$+#)&#"$)%*#+'&#*()%%$*'$(!%%'!&!*++"($$*#$)#*!$!+''#'&!+$!(")#'$*!&"'$#($#%"*&$#&)$
@r2805
CTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGG
+
5=+,G@8)A*D.8GA;&H)*)C/(45D!@B@%89H"),H(%7100)1H8+HC&#%?:;G'40#>&9@?:C0CF!F(2'G2CH
@r2806
CNGCGGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGACAATGCCAGCGTCGCGAGGGCCTCCTGGGCAGTCAGGCTGTCNCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCATAAAAGAATACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCNGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTGGNAGCCC
+
&&'%"'#))#'+(("$'$"$**)&'(+$+*##))$$")("+%#"!&))'')'**+*!"#)$!)*)'+!(&%%%!#*#$%*#)%$"'+'%&'"$!'))!'#&%!&+%+#&%*&"+$%))#*"+*!()*!$("&'*+"*!'&&%+*+#'$&)&'+'')&*!&((#&$*+(&+&$*#($#*%'+*$%''$"!'(&%%"(&++!++'"(*%+$++)***#$&')))+#)"%*+&))()#&#'()'#++(#"''##)#!"**("#*%#(!))('$#)'##$%+%%!!+&$"&"!+%('*%*!#!')"%***'++#*&+%"")*#!'"*'%*$)
@r2807
CGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCA
+
G>:C(5"7G"(/-.8&B0#CF!3:>A<%%E:51+@%//>@0H+CA.
@r2808
GTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCA
+
E,?#6.9"5'8%7<%A?!,-.#&!4"8';3%@#4-50=*>*)!'',(":E;:D8G<F;><5#F4E4<H;@H6
@r2809
TGCCTCTGCATNGTTCATTCATATATGCATCCTTGTTTTNCAACTATATAATTTNACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAANAATAAATAGATACAACTCA
+
@#14@!H'-./2*,#:.F98$%,/H8?=;A$<);8?<A)BGC"!!'FB90"'E'FEG9D5'B!:<5'<0%.0?'GD?/#@16E6C<$"#6$GD:%6C4B$H(-F21>2CG4B9E#G&.>H3:2:14:;:E%>>C<&1.&&E>B?(@2?F/72D1"*341BG*-G5
@r2810
CCGACGCANCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTNAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTTNGTCC
+
F/+,,;(&H?)G("9B5G2A*?!7*+0F<CH*+>/D%1*006=?7$6,#=?FEA+&FD(:?6'21-.-%@%1)!;E4--44D>'(,4#=87B&.1307#8-&,('=-.AC/#8*B.C1*/-G#"/+#9<1D6;D5$EHB>>(>:B7+?/(,713:6-
@r2811
CAGACCCGACGTCGGGGCTNACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTC
+
.&1-:.4#4@3(4:.6:@"4/!F%E''&/6<$3,"ECB44)7>C05%8)<=%DEB4&H*C"(=:2G*0"):')GE+-;%A>@7/??:#5.=
@r2812
GCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGNGACAAA
+
>0#01#G3;=*F5)*C9:61DAF>B%0):17A';8,<3&:A,"E1FH"E0%GB59.!!<?'
@r2813
AGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAA
+
&.":55+)A&$%2--?9B!;+3>1!5950.(#%@5'$;=#)9,980*3%<9D8;F9*#;73<0#0,?G3<B1G:F)?F0:%3=A0A)#,*&/+9
@r2814
ATGCAATGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCNTATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTAC
+
DG%=D'*03<>&F+?>A(4EDBB1@3B7'#5#)//#6.=0H?G@+9+,C>+.-745#A'#&)H<:)C&,/.+%+D)<*%63
@r2815
TGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTT
+
G&9GC0*B2=-"H0@*A86*0A>?(G%'5)&@+BF7.;G%"+!!
@r2816
CANCGCCAGGGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTG
+
*'&6G>ED)&.1@-$()B"&4C?0>9,-.)C#53GB/9GH.H;B:>*5'E<@$CH6%?CE'A?":.6:3C/"%.G":##(4)/D+$HC!F7
@r2817
GTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGAGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCNAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTNGTGAACTGATGCAGGATACCCGGCAGGAAACACTGAATGAATGCA
+
;-3(FC8'<D.*"G)-&;$B#2,*.CF'$5C)8*?,<7320#(-%C/+8+/7!7;6)85!5;A.,$'7E98-*D5DHA").$;,=#64=/0DB%5;9B#<76<CC%#29FA+2+8(!F#7G0B,56C%*B94F@(/==6%3;*-14G?*=3FF$B(,530%C9>@$3-E24-$16D9/H*8C462*9+.7@66D5E&,
@r2818
CGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGC
+
#?-F71GB+H164+F4C)2"!<<;D/?-"C!G)5#?-C+CG6=9!G(B45?=
@r2819
CCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCC
+
8%'>84804%/+C%E"*;)F62"6'6%;HH>@#C4H,>C(?9H:%DH7@GE/)!F?*0E-5);(>)"?:9E+83G3G%%)<39B*G3H*;723H@78
@r2820
GCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCANATCGTTGTAAATCCCCGTAAAGGCAGAT
+
7D,(=9@&(1$-9*8H0)?1=@-E-"?+#C94,&9-2+66":-A;9%:3+";?"FD0>5,18<3&8*,"B@)49*;%8!G%6*8;)'E$0>5)4$AH/A#B*A1G/-1,,!D0@$$B=9#@DH7;7
@r2821
ATCATTCAAACTATTTAGNCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGC
+
E#&0H0+'58<(9+294F#<-'@>G$2DG+H)'>/04=A41&-;(*7G,,<>DDE%<83+>5(3%7)?H%?/7+=#H:"A/5+C>5
@r2822
TGCTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGTAATNCTCAC
+
3%@BC2F6D4+&.+@=,,A6@3FG,8G3=D6EF(/>771(EEEG#/6G'5?0022/B)6'
@r2823
AGATACTCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAGGNCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCA
+
;G2)&=01>&;)#)&2*66@C$H/.=HC58-=:!@7,'+B8GG7&B%$7.+-&);+6;42,0(7&+C6?:?1C9)B8>!27&H%AC&C:;$5(+1>$E+:*4"5'D:7),3E/1C7*@?@2*$$.7G*,(%2G)=F-CB+8"-+(?.'*-C%*=4C"(.9;CA*%4'=,'0C2GB61:@"7/!'<@CG#
@r2824
GNTTGGGCGATGACTGAGCCGGAAAAAAGNCCCGACGATATGA
+
*+)'#*%'#(%('*!%&+(#*&$++'!+)+)&%!)"$'%(*!)
@r2825
NATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGAT
+
$>=*(6C,8:",A@!@72C!(?3#>15<,#/D:0)H7(0:&%#C@'+)<B#F?B(%>-G$*$E:?<%-C+**!7"7<@(7,2<=229)?".%(9
@r2826
AGCACTGCACTGGTGACCTGGAAGAATTTCTGCGGCAGTTAATCGAACAAGACNCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGT
+
C=-D4<9$;)==1?$'C1694&>GAHA#CG=&-EF@B">*'83@$2%F.5%;E9),/GCB+G%C-,=@>D6CA1)HG5@51C415H1D!,4)HAA8,@+H6;?/6G3#''<<A#<)&443@)B47,#'D
@r2827
ACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTAT
+
=='?2(F$!8,,%G+=.=:'0H05FB8;$'6>#3@<!:A52?A0+/4,::+C&%C'2D%ED(5?,=51/F'9.-@#'B'#B48?#2*!15DE(=GCG6C&?F#+2C)<H45#+&H5$9,DD=)&$%.
@r2828
TTTGTTGAGCTTGGAGCTTTGTTTTTNTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTTATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGC
+
D,A-7."D7,53*@CB)#5''C.'AD%-490-%%#1$FA1<08'%%B3.'+:>(6FA#B*.8=4*&?427F$>@@85'E*#8:;H85$?(':C:!:G@&8+.)#@H;2(C';)?D00,)=E./?;-B@G7*A,,!/(*CH=@*A@&7HH):?7B3E;<5?#<.4.,F@4*H1BC1#
@r2829
TCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACC
+
.8)<>;$+5A.F,E'1A#'*F,<@#!4,-:48$"=42'2"E50C@,G+>C;F%
@r2830
TTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGANTCAATATCAAC
+
8690.*3+(AA);(<(!%50E7CE935&#/$8AA%2E@23(?;)5.50E,&'!<&BB,B/8
@r2831
AAGCGCACTAAATCCGAGAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCT
+
>+)0H#F<//5+19="-F=>945#>B6A0CB29!5*8C*-'B+-E;?098CB-G)6.>,CH7BEB=97%D?5&5;1,9HE+%C6=09!>6#E.7(A<%!C:G9&F/E#7:F7E6DH?>:53/B4F>H=$1;:D)G40:HB:>2)3;?D#8/H.E:#")"@A++4C.@,AB79'?*:
@r2832
ATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGNCTGCAGTGTCTCCCGGACGTNATCCGGAAGATGGCTGTAGGGGTTGCCATNCACCTTATGGCTGCCGCTGTAAATCANCGTAATTTCCACACCCTGNTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCGTCATGACGCCGATGGAGCCTGTCCGGGCG
+
$:-@'(@FD0B0H:,'=H%%/*+%4<F5H<,)5<D=G02AHE>-B7(E?.B*2#AE>7E@5-'2HB'D4G'$A9@7@9<$B05-'4'C$4$59+&F5%B'17:+7C03!41<#?*+#G5/4/3:>"%5C9.4"F,)#:&HH-(<H#C%-#5<#5C2?,>C**D2!:21'6)*G?B%>+8@#6?D+70?H%(@#B<A+G>'@1#H:G)&@3@/A2#"E$%(6#;.:<2(+*"1%66203"!?
@r2833
TTGTCACCGCGTTTTGCGCACTCNTTCTCNTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTNCTGNACTTCTTTCAGATCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGNTCCCCCAGGCACTGCGGGCTTCCTGAAAACTG
+
?<E49>:BC=(;E"$B4':)66/76E9H.#";+&3CBG$4=?*,1"E2*1:@>(+=E;6=#F,4-,+$(8B73;E=C71F(G9-@G=@H&*=;0>!H.7))@"8."53<FG)>C94&.'-%A8E1.0/>8<2$,/=;5(FE!)H,<4,7A#?D95*
@r2834
GGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTNGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTT
+
1)1<8.807>#@0D+)@?*<:-<?:6::'7&@?<%&B2=?A%B;65B01!:E:)1,9>A$=8#;6*@%42758/%)&&H=78?1F/A;?4.H$1E),+49;!!7>H;8(;<2'"*;*G.C8#!/*4.@4'68';6"BGE*4&,D(1&:.-%1)<(13>5?8C=20*&)!#
@r2835
ACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAAT
+
H32+%"C05(:(9>?B,@.*=+#><C#5.#A"/,:<2'8BH;2=+2"(F5?-"",;:D@4?+/49&9$75+(-@9"#
@r2836
CATAGGTCTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAG
+
D!7*%5A1'E5&7&HA,9%(H2(3#6@9)321C-05)76$4D5%AD)B@%D$
@r2837
CANNNATGACGCAGGTNTCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAAT
+
%)"$!+%"($!"*#%!#+'!+!+*+"$)!!(!*"+#)$#!+!)#)('*'"++$$&+%&'%"+)##+!$))"%#
@r2838
TTCGCCGCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCAC
+
&%#($&"&(++!+%&%(+"%$()#()%(%+!$&(!#%*(!'#"%$*#(+($"#'&*!*('!'%+&(!()#*++
@r2839
TATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAG
+
'1,4!!26@@36>)G=6&>@2&)D,+0*7!B+,/>1B%G($<4)B.6E$
@r2840
TTGATGATTGATTGCTTATCAGNGCGTGGAAANGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTT
+
!63F+B"8#)168@-C%@@!E3&1+-'H-/G597857-+.E:@(8(1'-4":68B--5742>$-,-/5
@r2841
CCAATGCATNGANAAGGTCTGCGTCAAATCCCTAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTAGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGTGTCTTCGTTCATCTATCG
+
)*$')"(&)#*)'+)*)&$(!*'!%&)"$$')*!$'+!'"&"%+$)(%)(*)*'"%+%"#(+(%+!(&))#"#($()"+$!(&"%"+%"!)"%(#%(!+*%#(!%&(')#')%!%(%'*&*'"%%)$$($!&#*(('+&%#*)*$%'$$'$$+('&#+'++%&!'+"+)(($+&$'&"&*%+*+%)!!(*"
@r2842
CNNNNGCNNTNNAANANGNNNNNACNNNNNGTCATGNNNNCNCTTCTGTNCNNTTNTCACNANTAACNNTCNNNTNTNANTNNACNNNTATTNGNCTNA
+
$$!$##$""$"#$##$!#!#!!"##!""!"#$"#$##""#"!!""!!"#"#$#"$#!$#!""#"$#"$#$$"!"!""##!!##$$#"!!!"""#!$#$#
@r2843
NNAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGC
+
$#@=1A">>!.BGC#)9))*BGA0!$?//)2=CE<+=GF1-:-5./:9,EG/A=G8G>'(3,>:G+&
@r2844
AAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCANAGGTGATGCGGAGAGATGGG
+
!3((2'',:,4<*1B=%;+,!'E!/+#:2!-5=H$B:-34/+9F2F3<H;)<.#6"G04A.##52.5*:4.#88B$%.)!4#>"E?%?#G#/"*?*<D9&612%3C-*513=7>".35.0>?'0
@r2845
CTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATNATATACATGGTTCTCTCCAGANGTTNATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATANTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAAT
+
@-C3E>0)HA+-&*#C"1.A+@F?#'3&6(?4E<!/4<4/#A4B%A.9<@8-.=$%9%E2C??F*)AF%)(18H1D=;5F),#.?0<=9>'4-1A/@/'010C1&;7,"-(.89<"0#>.*='7+)7$1:4!E)4$1:*'6=G/A<G.)!D)H4%BA3:>4%;+,-;:E,8H#7#4-/&4"2B4#+8E)")"%@C!/G;3,$&>;#$5
@r2846
TCAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTACG
+
/#B6#@$5E>30HD/&),"8$G4H3)))%*DH,(4@4)=>!*A7=
@r2847
TATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACA
+
>-&?).B,00$8?GFD)H5'$C--"9>=:F?@""="5%:2>$2G,6)FE2-:%C.(4H>)$D>3G9/#1E'13>"F'11@8C(+1!=#37<%C/GD-A-")0
@r2848
CCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACNCTGCGGCCTTTTACACANGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCT
+
?C2+C:<E.627?E48*96"AB40"B*>/.H**DDG$>AE&/=?-D:;$5E'$;F)A$!'(%C2,=+-E=#G.1-C60:$81'@6&"$$9!?H,GB-6>7)%G,&0,<*:<)8%A7?)=48.79C
@r2849
GGTCACGGTCGTGGCACTCGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGC
+
C61DG(4,?:5:",+=#56+&<",:!+C)-%<(0E#5*)33D)H:--;5F0D6?'=!?/"=)",!5/E'?H4.23?"1F)54;D2!@7.(HBA0)HF%?C&;4).=+/);=G%/11#
@r2850
TCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGNATAGCCATAAGTGTTTGATCCA
+
C:&D0(/&H)C!<F=.'?>&&;:$BF99-27'57.+B/95=#.F)@0$#*GG9>.<<%6-')AB3'"..,?B<D>,0DF<(.6)A?5&F%,(*?-;"F.-!G
@r2851
NATCATGTNTNAGNAAATTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTT
+
%!&$#%&"$!$)&'&#$!)%*)+%*&(""$$#'($("(($+!&&%)(#+)
@r2852
ACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCC
+
E,'EC+!64BF%/E="H7*)'H7@A$?='G<<H1?EF?14!1)E":3<3C>'.57/,A7(2H8..6@H++2!
@r2853
GTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCA
+
%5C1H;?"A>;?!B-4&>&'BF?+%$=BGCC!$G=%5:(H0$49&+&(
@r2854
TGATGTTGCCGCTGGTCGTCGTCGGTTGCNCATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGG
+
$='1:GC'D1#*;G/3.026'@(A;+"26:/8C"8+@B(!%$AAG07&-"-EE)B=:#30;0<+>.,17<CD;/9+.6HGF+%
@r2855
CATCACCGCCAATTGCTTTTNAGACTGAACGCATGAAATATNGTTTTTCG
+
:,:E-!3D;-8%!(=:.?@:0#0A82+F@,E+@*:+G0(B2(4FA''B0!
@r2856
GNATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCC
+
%!%'7B5$?D3@G5%@;)<4B34-@>C?%)0F,E4'6&)%
@r2857
GTGAAAAATGCGATCTCGGAAANGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATCCAGTCANCTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTNCTTAAAGCTATTCAGGATTTAGTANTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGNGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGNTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTT
+
D+9&/(99-C@",5EG$H$C$G9FE-,139.B3)%+()!C6'D.BF.3H@C11+D+@"0+/4+)>CC$"HE<:7*(/8*%3+/00%-3-#?04@(?B>%%6'?-FD:%55#C(7'$'F;0<9%/HA1:4"'0>A?8=;G(!35&3+9:%3#F'0CH(1+$988%!?)#H3&G?F!:(@$!?D(#"($;@7%2(1,:7#;5*-;$9!-B5$C8F.3)1"G#,"7F1A9+'))HD476.*3FF6<E$-?<9G02:0(*$&.6*+F"!6%@-958B*&!3.).(HE0$)5G0H;-+AG;9&#61:@=BB5B>@-/6<%%/<8?A(H&=%F.$?,/?$E4+(:/0A,21,&
@r2858
CCTCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGNTCAACGTCAATGCAGCAGCAGTCATCCTCGG
+
'9!&5/2=G,A+C/7/0$D!?F>'1)%0F3;BEC)'!).77+B?#<B7'HB@@%21*;&3?+!E;<:13G7G;2<46(#(/:G-"5&7:&*(+=H>9H$#2E+"CB!4G4=E$?:+2H+"B$-2@AD,B<4<F/$D<89?,@/1-#/:E+2=D#',%3
@r2859
CACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGNAGAGAAAGAGGCAGAACTNGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCNGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATNAAACGAATGAGTACTGCACTCGCA
+
AG+#GE#6*9(@0(E=+C'47!7%+#)>@".)8F4"@B7$!>.&+>&,)F7A!/)@2/6,=5@'GH;8((2@,H$5&)BHA:H+C+,7%$H'&;6*1+3:4E&/-5%&>>5-;@"C;(/@H'%@&?"*#=3=77B$,C=#F/3E9#>F,GA#4@+54,:B=D=.-H!+B2>=""H00&4:G.>?$E*G-F07)E?,C=4BF!AD:F7!2$F%205(+8173D%!F'E/,9'21#G(%08-?EH*<1;0(DE',21,A?C.E*.D30B>"8$;7!E7<BH8D>#EA><<)*3))*=?#1(8$9AF*"/.?1$",2C)/)!99>#@-6@;->=(?&/%#653
@r2860
CCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGNTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTANCTTTTGCCAAACGCGACCAGTCAACGTCTNAAAGNGGATTCNCGTAAGGGTCACCGCTCCCCTTAAAAACCCACGCAGGGTGGTCCCNGCACCTTTCACCGGCATTGTAGGATTTGGTACANGCGTAGCGTCCTCACATTTCATAGGTANNGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACNGGTGATCAAATCTGACATTGCCGGGATATCGCTCATCAC
+
+)$*'$!%*"**)$%#"('*"(!"'+'*&)&$("()&!#(*++)!!($!%+(#*)&$!$#(")#+!!!'+"''+#%)"%(%)&$#+!!&&+%!*&&$'&)!)$!$#'*%*+)!(#)(%+#*'+%%+&##*%!(*+**$*#(*#(''*'((&*'"")#*+"*)$*'++#&(*(#(&&)!'#"%&&%$&*"!$+#$&!%!)"&+$+"$%+!##$%*')("'!!'&"*&($(*+!$%&$!+()'*&+(&$)%(((#(&#$&'&*$%")!#!(%*"$$(+'!$"!$%'#"")&%&*+*%#%*!'&*)!)))+#(*%&"')&*$&!+'$%"&%)$*+%)#$'$&+!)'%+%('!++&%(&&"&&#)#
@r2861
GATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGC
+
+?.:>'-139/G'710(27/;H@*D&C*!<8D<0"7-368!/1$%=!#E@4F@8D"2#E<G.@D?1!2
@r2862
TCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCANACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAN
+
5"0G#->A:!1049$)4%F2&-C1*H#?#F6H!A/A;-6@BHF:6>/A-82C)BH(>$FAFC?-(+#<:0)8?9:)<0$E0A+91"92A6:'0A53=3
@r2863
GTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGNCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCT
+
:=63(>D(@'3C8?720F#B<0&43+";4#:@G/"B1B*>063@?=$B@,H;2@)2+G.B4-H5(*+C+<)528F11#"7C21&GD8:17"G$E5EE*E2<=$9".G,,5@
@r2864
AGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCNTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTCGCTGTTCACCGCCAGAAAACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGNCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATNCACGGTCTGCGTTTCCAGCTGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCC
+
8+50:;%=#$:+GD<-=7'=G-6F(369?F).4/BC?16B-#59&((F36*H=3>=G)!C,"1403!AD2/#:1%.!)(/+?E65&)H=;@47AH""/#-E!+777:5G()-GHF44"5:6"EG2=3A:"&?B%D6@20-C,=%178>9:>?F%CH.>.?>,(F1?"3E#9:2"(!<&!)="'-;(..9C91/,/6+?H-4@D9E/2%)7+02/E2'!E)>G5G=01A0A:&#&E1<*B00,?BDHHH&9421E=A-A@!+G0:,8>>(<3)G"5HG/&C7)(34&2@6?<B2?*)#"78B67%+FC"74(+B%.'D*1F8-H:678"
@r2865
CNCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGAC
+
"#>6?0E/->)B9;G"D,14>0#4;2<21*"(B<:>&@;7D$05F3&":6C3*@2AH0#128/*1=$7-A/,A6<-#/8.D2-C'3,;5.?GC"&2;:B@!%E>4/.4@86H*0/(:$(6@EC+/
@r2866
GATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCG
+
C;?-(G8H!-%>G4B=65C7@0D=$=%<&=B(+:A003+,9/A9)*,*/C$)/?(;"923$98!'920@/'*24(7)62&3,9&2B8A">%B'>"HB9(%C71,74"-1:=,D,"!9??@-!
@r2867
CNNGCAGNNAANGACCTGGGCGGCTGAAGACCAGCTTCGCGGGGACTGNATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGA
+
###))%*"(%)*+!%*#"#)&!*!%*+'!)&&)+%"+&##$)%'$(!*+#)&$!#"))+%!**"'&*'!")+!*!$'*%)')%#'%!
@r2868
CATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTANTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCC
+
'2G:,1F0B<?##AD'>6F?9#1-2ABHDA5@AD%;$64A55E66A,48'C)?.!3/+EB*@@.*9*/5;G#D)!<2&H,G#1.%6,$6-?0)@>8?*6<2<>'EHC3:G,$8:H7H/21(++($6,E8/+FH%*CF28$E&7+A4>;3+&!-75D$'H2A%8E"<+;&#%8B1.)8D!):6+2H@#>C-;)'B96B&F3#?$<139
@r2869
CAGGNGCCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCC
+
')"%#$&+!)"*+%&&*'()'"%!&'$$+)"$+(#(&(%)'(&')$#!$($$%%'&'"#
@r2870
GNATNCGNNGGACAAAAACAGAGAAAGNAAACGACAGAGGCCAANAAGCCTCGCTTTCAGNAACTGTCGTTTCCTTTCTTTTCANAGGGTATTTTAAATAAAAACAT
+
!##$#)!"#+**("!)#+!)$+&$#'#(""*(&&(*$%$#*""$'+"&!&&'('"&++!"*!''!#!$&#$"$**%%)(%'&()&(#$+#)"!)(#%&)"'+*!*+%
@r2871
GNNACGTCATAAAGCCATGATTCAGTGTGCCCGTNTGGCCTTCGGANTTGGTGGTCTCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGT
+
($!+&'&#+&*!!&*'#+%+'$(#%#!+('%!+$&%'#'+*'!+#"&)("$)#)#$&(!(+('#'*+$()%#"'(*%&)%(+!#$&+%)%&*$!#+"*""!&'#)&"("*'**#'
@r2872
CCANCCNCNGCTNATAGNNANACNNNNGATNTGNNNANTNTNANNNNNGNNAAANNTAANNCNGNNNNGTGTAGCGNNNGNCTANNNNNNGNNNCTAANNCNAATAN
+
#!$!$$"$!"##""#$"$"$!!!#"$!!!!#$$#$"!$#""$$$$"#!"!$##$!$!$"$#$!##!$##!"$$"$$!!!#$!$$###!#!$"!#"##$!##""$#$#
@r2873
ACTCANCAGAAGATGCTTTGTGCATACAGCCACTCGTTTATTATTTATCTCCTCAGCCA
+
?12GH<9#7#+("6;/*23092</(==0C?2F<HFH%+02''!E%854EB=<@0F).,=
@r2874
CACTNGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATNACCAGCCCACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCG
+
$$*"+'#!$!(#&+"(!!$($%+#$"+*&)!&"*+#(!)*!(&$$""*%""#$")$!&")&$)''+("+%(%#!&(+*##)""#!""%(##*'#)%!)'"!#')%$#*"'++')'%)'%
@r2875
CTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGC
+
3?30?E5!7F98D<"!-4?2%C*A;C!F7H#>47&46FH!'2?!EDFHF649
@r2876
GTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGNACCGGCGTACTGTTTCAGCAGCACGCTTTTTA
+
4D*?5%-4($)&.B*'2903D7/-5:!1F>-BG)!:FE!=H*7A*!(@;!*490A>;9:5G),/+76C(15
@r2877
CGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACC
+
8(G-;/#'4532:DCF/GC2CD<;D83F8!@E0',,G@*95%7&?3E1$AD&
@r2878
TTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCA
+
@<'-!9D"6=>=/.3E#E'-6-4@=H"B%!9<<9C'#C4DB(6%#A@%&CH#$4%F,AB/-HCC8<*1B(H/'=,$1&).A63,B!>08AA2B
@r2879
NGGTAACACGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGNACAACCACGGACCATAAAAATTTATAATCTTCTGGCCGGAACTAATGAATTTATTGGTGAA
+
!)%%%&&%+)"%"+"'(#($'&'''))+&$&&!&'%)+"&'&(#&!'!"+#'"'%$$"'#("#&)$)%#+#+((&&)&)&+$'(+'"#)+%*$#!#%*+$&&&"!#)+!))(+#$(')*')%'%!*#*%+#!%*%'&%*&$
@r2880
TATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCA
+
0:B8$!<H-<GD.87;02=;(30,25F+!-.$D43CC"8A$C,!@8)-(@47*=00'@&B<H1<+/31>:,/().#G(>A4E5G9"6",A"<1B,9!>94"$:'!*%F#&7282;#(5%)6EHD5<'8+F%,=:$4:.#?%5,1/>2!AA26F/=%0$3;EC2=@5B@<$>@A/
@r2881
GCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGACGTTATGATTTAGCGTG
+
*/<$67%1+&*(>"GH$%=*G*!E%!$4<&=B0#==D.!36##?0&&-51@(-HA9(;;
@r2882
AGACCTTTTCCATGAATTGGTAACACCNTCGATTGTGCTGGAACTGCT
+
$.ACC%(,4C;/H&&7*95&GE(H+D-9#7<'1E2.+7$%+C7BE)*)
@r2883
TTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCAT
+
40;C(5158+BC2H%=,D-@-0;?6;.6DD6HA2BG*1D*6
@r2884
GNTCAGNGACATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGA
+
%"''"%&*)')'+(##%)*'%(%&&$"#"*!)%+'+%(#!&)"()+%(&)!*!#('$
@r2885
TNCNTTGATTTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCNCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGACCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTNTGCGAGGGTGATCNGAGTAATCAGTAANTAGCTCTCCGCCTACA
+
)$)%)$'&+"()"$*%*&&"$&%&&%%(!""''!"&&$%!'*'(!+&#"$()+(#+'#(#$#&+)%('!!+"&)'&"&)""#!%'("+#(*)%)+(*%!+$(%*&+*('#$')("+'(!(!((%)!%+**"$"+"")"#'%+*$(#*#)'$!!*!$&!*$+!$&)&'"!#&#"(!#+*!"$)*%%**&&(**(*+'*'*#**)#+#&%'%*++*#)))'$)$'%&#"#*&!($)$(&'&#$++$*'*')*%'%%)%**"('+*"%!%#*$)+*(+")%#)&%'%!&"%#'#)$)"+))$+%'!$!")%%)!"%+%%%(#*&+%"""$"&+'(*!%*(!'!!(
@r2886
CCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTTATTGAATGTATGCAAATAANTGCATACACCATAGGTGTGGTTTAATTTGATT
+
A:G5'5(&B%1&@H22G5+C9@'=CC>5F+<@!20(&*:#D.=!GB3)"GH>&G+,"6E4@%"AE+:CD69:$,(6:<")((&(&@;9$#@G?/''B,,8>E2D-).=@>*D<$F:,)5@:H0.<@4%=-,@@F$'3'>/H<:-4@$*44F74!*3D/:/E,8.,"1;#/*8!9?.8="$EB06B>$>9#B:-H;F((7D,>=9?@
@r2887
GATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCNCTGATACATAACTCTTNTCCAATAATTGGGGAAATCATTCAAATCTATAATAGGTTT
+
':3"-#5%$*25D*1!:CG<.9+%4*,032.ADB@),0@)*=E'F<6!4>,@D0.-B'"F,&H//GDC#>)!14E%'154+<4.'E:<==D:3
@r2888
NGGTCGTNTGGTTNNTTCTAANCNGTCTTTTNCNTNNNCNCNGTNCNCGNNNCGCTNNCNNNANCACNNNN
+
!#""#$"$!#"#$"$$$"$$"$$!$$$$"$$$#"""!$$!!!!$$##"!$$"""#$!"#!!!$"#$#!!"!
@r2889
NCNTGTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGA
+
$$!%'+&$!!'%*%(&!!))'&&('+(*%+&#&$"$""!%$"#%)%%%!!)%')!!!)*#&
@r2890
CAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTT
+
HEH,:8#EF6-194$8$*8:2A(0>1&;"H5?E-&D30E9=>)CA8E3*1H2:D+3<93-"@!C#29:-=3=57507%6$5A
@r2891
CGATCAAGTGCGAAAAGATTTAGACTGTGAATTGTTTTATTCTG
+
9!"8-8)4</9F1DE4>/*H<9!+;/#C(.#<5-F64<'4&;G@
@r2892
GCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGTAATCAGGTTTGTGCCA
+
,>(%$%,89#FDG,A21-E2BG0)B##%;+-$D:<,F*5/'>.<*;7+"FE"4$0DH!#%,E5>AE1B#,4&#7A!86C&#C
@r2893
AAANGTTTTNTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAACTTAAGCGATGGTTNTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGA
+
:BA*0D?C0&@(23:1*!6=5"-F:B%E-$%=239"'G9(9>/"*958:20-&4F+$HFD:D6!(7$'*'9B9'8.,65.6*E;@D+&9BEFC>!3&$F/6"?)B,&3&B!)%3/?@(<2/A.<G@G>:%.50B:F'7BC7(%%B=**2;#)<!=@;;<H+121//+!7C+G&/GB*3;F1&<"!4$AG%2/G=
@r2894
GAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGATGAGTTCAG
+
6<0<3%%+'%;"0GH5:*5BD)#"BD"3<1->E37%A*A8-7$:3/'+1+@4D7@D;1/85&5E<G(="G%.$>9904BG+F+(;A6'<A-9'2H#*B-;9,%7FH<747'*=
@r2895
CCGCTNNCAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCCGTTACGCCACCAG
+
*)')'$!+")$+$!)&($'"+#(%*(()%%)*""#()++&&#"#(#)(#++())+"**&&!)"*#)!*"*'''"")+
@r2896
AGGAAGTGCTTACCACCNGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTATCGGCTGTCTGGTATG
+
04!80$CB?<EB?5-389%&G;?>B'4G)3>EH'70"=HC301:7?$$<H2.$628=<"9E@,&9+!9AA;&,<
@r2897
NTCTTTACCTGCCCGTCGCTTTTGCTCCATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAG
+
-8,6GC>!$8'50(7@B)19#81B3B(;?4#@%-,6/#"+E;(AD-.%%!3$+.#FDD:G>FD(<G<
@r2898
TTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATACCNCTGAACAGACAGAGGACGCCGGGACCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAANCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTC
+
5%*786'#H@'@'@:!7,&+D7$B3HH/;E-0>,A!7!%01@C''7@*"(5@7<.23:"4213@'8&0-&:)/%#1%<1++,>5:%A>F4&79/.@@BB22-@E@G281A?9,"52>.$2*,4,7"%/4062B?F:20(!#*??3&&7-65+#+"#1:HB%*!('D)<6F)!#*3.-7<80#D=7BE!%0E/+?3G?)8&0&0!((H$>+1A:!#.D6@"&)')CC)CH/%/@/4B8BA2F?C=&@='05,
@r2899
TTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTNCCCCCTAACCTTTATATNAGAAACAATGGNTA
+
,)/"@*#/G%C=8-8D<13,@+$G#</E&B:1%F<2.'"#1-&:54338-DH@"CC;:3F.7/BCH0<!&%!B+HA!<F42ED":%
@r2900
AATNTATCGNGTAACTAATTTACTATATGGTTTCTGATAAGAANCATTGCAAAGANCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATNACCTC
+
$$&"&"!'+#'!#'*!+%!)"("*"'+%&$&$!*#!!$'%++#"'#&+&'(&*'(+")("%!*((+(!!$'+"'''$')**&)&&##++!&%!')!('$&#*('!
@r2901
NANTACCCATTATTTTCATGATGTTCTGCTGGATATGCACTTTTCNGTGCTGACGTACACCGTGCNCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCNGTCTGC
+
()+%!)$!(##%$))&'!"+#+(%"("%&&'('!*!"&#'$%)!*!!(+&'*&'%+&"$*+#')("#$#'!"''##$%&*('"%*$'#&))&%$+!!*"$%"')#%!'"(#)''(!
@r2902
AGCTCTAATAGCACCGCAAATTCGCCTACACGCATCATGCTGGT
+
+(!)('%#+$"!%!)%#"#$#&!&%'+#"'(&%%)'#%'&'$!+
@r2903
CCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTNTACATATTTTTTGCATGAGAGAATTTGTACCACCTCCCACCGACCATCTATGACTGTA
+
:)215;0:>:&B$H<',8C-.D@.D<:0/8!!;.*9'H::%1E/H7G93F,9;E7%1)6E(@39+#"/'G6,:DD.0$+>#EF'D7,@.$1?7,1223A1<
@r2904
CAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATGAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGGTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCG
+
A?#6<7(/)*.A.@A<0A?#;8H9)+5/#?66&:#E&D+-<6A7FF-)78.=?E1*9$%"(<//7,"2?$93*0DD=/"+CB0%"G,E<*45G2="28"'H17=%7;98D,//"&6:F)A:8!A/':'8-79F><01<'C/:'-;A6&0'$1F++0A(".G7E5,&*,59?7G<=85B59
@r2905
ACGAACAGAAAAGCCCACTGGACAGNCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGG
+
C%>F.>;<$D!$%GG?4A3,1?6+9.?;2C6#1!HGH!(F0*:2!04;3%3H/)!2D&!1?.+ECB!$
@r2906
CTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACA
+
%3=@>A:D15G>6)%&!FF)3##8DEA;.'38!;&6.#82=A9%EA?DG)9#-(
@r2907
GTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCC
+
(F1H=9=9B)(8#B+,0B":))+?5$.#;'D2:9?D<G1.32A/7.-3(A'9>/0).5A7F$#A5:1*$-6*@(/;4,D1<;95&$08B-F+2)$GE54C88&3,?-:31G18A6:7#-&E%$?7-B$8';$@
@r2908
GGAACGTCGGAGAGCCTTCCTGTTCGATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCNCATCCACCGACTT
+
+9/@#51!"*&&/1)CC3!F80#4D6<3-9.-,/%9(/E$(G9#$&9%"-%!@E5+@'B*27$"=4E#GD+%HH&*,0;
@r2909
GCGGCGACGGTTAACGGCAGGNGGTACGCCCCGTCCAAGCC
+
A6-HGA(21:.153C8)0;C+BB4<08B5:<7G68%)G0$:
@r2910
TCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTT
+
.:;A;'1%@/--9!?9.D<%:B)B2<8HD8,;7&%6B6<&=BH1=+AG?#G*2:'@4;2B;*G=3"+"8D')8
@r2911
AATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCNGTA
+
,D!5()<5,)(4(*)<8:,89&>0C&0C'7>1CDE/;.3@+1&.3
@r2912
TAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTT
+
6@(><B@04.3(D+>>*%H2/?ACB,)(3@D&DB;50/:>2;'EB0H&2$%9A"2
@r2913
TCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAANTTCACCAGATTAATAATTTCTCGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATG
+
BE'25,$)B89$1$'$="H!(0;8+5'#2><G#F%2$1;(BF)6%-.C"$>'"#$FEC"D";6HC95(<A!19"=##"&?@!.F<F0$:"=)!%*40EAD=A";'DG)+831@3#>8302+D'6!D1.1
@r2914
ATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCAGGCTGTCGGCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGGACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTNGCCTGAACGAACAGTTCACCGTTAAAGGCGTGGATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCA
+
-89/)&;,G0H5ACB)?F%;D=,>F3+3"".6,83H.8'99>=#D#?;-?G/-,H"631?C9'%"'/;EC"C3*#(?%G"+:HC79,,9857%DHB/5G(<65FD(%&83CB$AB$CA>-:+<#3$&6G0<(,',?3$6,C3;.83ABD8';F0D@8G?:0A&(A?<$HA$E@">B/%'H:66:@':.B+0C9>%09F0:)&4?C69<2);3%+1($,/<G.008*)-=0<GE>(51A>A*75%A+71BG>);200>;?G:G6>A3@"4,!'0=7CC4)$
@r2915
TTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCGTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTNCGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACANACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCNATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACNAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAG
+
A5C4>&A9=;0:'+%8/9#8B0:*1</FD%HAB7>>!6#61=(%E#!69F%4<'B9"</:3-,0E+G/.3%A#'G,?62/,?3,:+++58&(+A)F77*H.5>F0->62FB<;3--*9'1$3FCD9$,C&809(45C3--9G83(&-,/F%4-#10$F4*'+-?,,H$+"0H?*8"$G,+$',"*GGFH4B;/C-FG;EC+@<&%1/>AC":?//6#!+!@GC(EG;G*/0H5;A#;4;8/#B#'30%*9>5.;F7--):8FAB8;C9-:H63?%&#$F6&40<:8/54./0=(/:@8E,"=0GA5D(D89:)/+*(/,.6$'*1);&9:+=(>$6HH&?0E>.<=-0#6AC0E3?B>/AGB5$=*;222*+#>&(CD!#B$8,BC-:-<?D.512CDBF)3#-%82"=&0H2&=.7@.C0-.!1/2912A-?01$'#+<*B;
@r2916
GTATTCCCGGCGCGTTTATTNAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGT
+
;6$":22>4/<B!A?9=A2&E*13/@)/.*?6E2=>C>#*4=G&'B;,(57%3&73'7);.*&CD3C6+?G2D@#B+
@r2917
TGGACGTTATGTGAGCGTGATNTCCGGACCGGTTTTACAAATCAG
+
'+)&$"$&"'$!'"(%#+)(+)'!#'%)%'$&!)'+((!)!"#(%
@r2918
ACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATANTCTGCGAAAACTGCAAATACCTTCCAACGAAAC
+
:#6,54F21/!(AF@E/2BC?@-;%(%3<$5!E)8!E,D=>E83+@E+:>2,?7!'<%2BE2'*E"5:60%+(3D(H.:@#$;7E-(D6<)A8;
@r2919
NATGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCG
+
%"+("$+*"&%)("%!%+*%!'%(%(")#)+!%'+&%&#%#%*(%&)(((!+
@r2920
NACCAGNACANTNCCCAGCGGCTATGACTACCGGCGCGACGATGANG
+
"")$*%#'%&%*%"$%$#&)+(&'#"!$&#*)!"%#(&$%"(+!(%(
@r2921
NCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCAT
+
(;-.+>@+G,=5C=-49,:+#6<12"-%9;&A0=#><(?/-"96-@@!#E*2+.@(&0-6)?/&D3)D?9(2&)5>2?;DH2*F/9F0H:!;E11648:#FE4-2D7H1A,%A="(6<>%E#"F?(%&H=E:0E9"1+>%<4E)A4E<3@$;E8157==GFD;>"46G<CDH74$0((!9E<54=-*!(GD1+AD,3EC='0=&#-=3A2%9.:0&$<715>(F%<C.>35$-30E1AA-<=B@7"C6)%5*$*!$0C&F>,1H(%0
@r2922
GCTGCCCCCACGCATTTACCGCCCGGACTGTCAACCTGTAGTTCCCCAGCGC
+
/6';D55C-'9?'";G-)$!@*;%#C=@?.=?5<()3%'-46#':7$(1%G*
@r2923
TCGAAGTGACCTACTGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCANTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATNGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACA
+
>:;H=(G!A%+3C"$!H),$3C/,/7,)/9:%?'EA5!*@<>?.?:>H:@58!>6$*<4C1;9%*0%'!,&=G1&/98&?.>>:85A=0H<))$89(-,<H6G84?(H#>%D9<<F*D,)E4F9D=H5B8H'4>5*:#G'G,8H"$((HG27<'@.C7C802:B7AE">?/&4B!=>?<0C$DG-4"$#A&#67G'F4-190G():8C)<G31:2;*/H2*$G?5-0B(2%461"2A="C5$%58!)AB4F<"?#BB4
@r2924
GGGCAGTGTTTCCCAGNGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCNTTCAACGGCGGTCTGTGGCTCCGGCCTNAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGAT
+
$(3@DE6H=99?$D*>E'F?1D?4?8E)>8CF,&+$7E>':,55>#8'$A56D<*?$3B?"+3H12H&D!E$:11H/*&E($#:-&=A3.HE.?:5&4C>9>?)H%H/9#@<$#(>7$4.=3D)/%0BF<9+073,C##9<-*"1G(!H-"E5H;3$
@r2925
NCGGCATCTTTTTCCGCAAAATACGNTAATTTATTTTTCGCCGTGGAAAGCCCTGNCAGCGCCGTCAGTGTCGCATTCTTCGGTTGT
+
";=:@00=>.C-22478GG%F/=$<DE0#F?*0%#.86A;-/=9'5E>"<-"8+5*;$>AH3F=0+:?G>BD.)8291G,&&G$&%1
@r2926
GNANCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTA
+
+@CG+;6%F)!!0E>*37&$/./3$4AG$G8C'*4F'<71+9">!<3!!4D*72$7%'-(68CG6)71&/8;)/E
@r2927
GTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTT
+
A$DG46D67,GA2-H3E(,7'EBA'G-CE<6@$E$*-/F1(6?73G><?
@r2928
GCNTGAAGCTGGTATCTCCGCCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTT
+
<="%D%1@!#=F4A1C:6H8#&178$#?)!471DEH*"@(-2FF"G?'&G+6)H6<02*,,<6
@r2929
TAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAA
+
:?D,5D(;!&C0&5*(%9!AF)F9F1CG74)#AB&<+$/)$@3:>?;;?7(6@549$<0-2$@1'(>?+B'!A)/:9CB4?(.@114F;EB70G<%$A?1(A=,$'6H%03@07'2"'2+9.<+HH96-)D%AE2(6;B7+2?;&C6=@,D9&*$(+A&0(+59086?A8FD%*.*)+A+.C'?FG"F($$0-+55-%
@r2930
CATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTCCCACACACCACCAAAGCTAACTGACAG
+
>;A9!-1E(>-&"B/19B>)0@E25FC2'FCB;C824410%F%A,@2?'0+<*5,;4/D>4:$6F41GD6)0=;$H"(');(G.'$.41()';(;!=1&(4$<6+*@@3>=5),8?9;7-)A?GG>2'8E*=C<F:8;:!:$<%-8
@r2931
GGCATCTCGTTGAAGNCCATCGGGGNAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTC
+
+F9EH8+-!B&ACG1D<32BFE&?54G@(F#%1F(:5FE@9(A4?5#,>EFF,00-+7$/.4,5$C3H5$
@r2932
CGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTANCGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTGATTCGCCATCCTGAGAGACGGGATTTACGTGCATCCCGTGCATCACGCANGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCA
+
6*%&9C',2,F=+96)5'4:7411?F=,C3+0*0G68>:1E*!*7C<5;,<>))1#48F5$H1F%H."%&#FC*8.F<F6#3A!:AG6&&+G4G(67!056C)7><51!E&,+)&1&H-F5;DAE");<,$"BF/'8A9&?;7@$4$"589&1+</0:;#C(2F)4E(2AED/C(?04*B2/$.*-:)E='FH>03<,!7:%E+B%:''&CC):<&B2B2772016%2@D;EB(D5+H#A&>'%8!0+(=9$*A+G8+@<
@r2933
CCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTAACG
+
@--=+/;)7/DGF<:F<!&1F72>,D"D>EB2+H'=@+(;C:!)%=@B".;+1/C&
@r2934
TGCACGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAAT
+
'%&$&"*$'+'$!#)$"*%$&'"#$#"#)%))%"#$!$*&!*')$)%)'%&#&!)#(%*)*'%+&!&++&##('))&)*(!)!*$(#*)'*%&#)%"(+!*($++&+!$*&+&!+#)&*&
@r2935
NACGCCGGNTCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTNAGGGCCG
+
"++*))$'+%!)%%&'*'####)!'#&*'+'%)')'"&""'#"&'%##%!!"+(**(&)+%+'+%$##$&#&+$**")+#(&)''$"&%(**$(!'"#!"#&"'))((%
@r2936
AGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTGATAGACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACA
+
)33:?GE:4"5355GB"-HE:C172C4*5=&"64/9$*8/6(;-:$FF!48D3?!0E9G?C13/=+:->D:H59B"F+C.1,E?1A?6+4"9+8#EA/)#""C/D+0H#=!;B"
@r2937
GCCGGGCTATTTTCAGATAACNGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTNCGGATATCAGACAGGTTGAAANCAGCACGCGT
+
#1#*/*7#,$+F1$3269=E,@%::G.1-<=C6.26?B7",2?"(9<#,(0*%E@.&34A8'8H+1!5""(0,8-+,0=(B.(3&2%71:)>39-!)2&&@C+<#79+7#"C(D'3DFB89E-/
@r2938
CTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGNATGAAGCAACGCGGTT
+
>()#5C4F/!)0&-3'FDGF0!5@EC<.)6<-A,D()FC="98HC%?=C=G8AG>!B15>2F@/F:)4$'>"G8-B0&;*7##=2,$=3&3;4#EC-;#@)CE="?,CG:B?1$A?E),->*0@01B':275F337@,9:2928H@-A*(5:"E3-A!>.1-%2'
@r2939
CACNCNCGANACCTGGGCACACAGGTCTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGTAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATT
+
#*)!("!))(+'*)##*+$*$!&$$$##&+%##(#)+))$%(&++*+)(+*"+$&!*(&(!(&)($($$'%))+)!"!#(##$%#(#*'"(%*'&#+()%+%$((!%!*%)!'"!*()(#)"!)("*)$#(%"$$!''(#""#$"%""(*($*'(!+)*&+
@r2940
TGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATNACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGG
+
.,?>976,$.><.*@>F1=G.//(,B1G8C*;;B%+05/1,61:73+>;<#A/*?&G6*H6(7;=.H)-??/<1.7=9;;G-3@@&'':(+4G60(E)91@?3A+7!26!;"D604A1*3&:0+?(!-6!C3D08&CA(>F
@r2941
GGTCGGGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTA
+
=&:#<H$E*2'G?BD,99B'0=:FDA:B@!C21E;(#F#FA$#+;B80A%:<9';1=F+B%H5;8
@r2942
GAGCTGAAAGAGGAGCTTGATGACACGGANGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAA
+
=?C7:0-GG<%D6+6=@@09F;3AF:?:F3>H%%!F%,>')D,49+10B)?.?B19.G1<>,!<<B
@r2943
NTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTNACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTGAGTAACGT
+
'?"!B!<#*?=<23&+!2;,=8A4?8-4:A("/5%+A2GG-F)/-BD9C&B14DH$'C<=:5"9522?42<E+@0&>89'@69=8&))GB2);E"B#/C%)HF!#!7?/)#>5C)F:5,G%6.(5;A0G0!@#:8D0+:,58-C$4F/E;;$&;;6F%,#<EF
@r2944
NGTGNNACCANGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGANGAAACGACGACGAGAGGAGCAGAAAC
+
#&))%"&)*&"+'*())&%$%$+)&%((+$%"*)*)+'+**$+!%#!)%(%+#$((+&$&)*(#'+"(*"($!*)*&#*!!#%*'"$$$%+(&%
@r2945
AATAACGCGGCGCCGGAAGCCACGTNATAGACGGTTTTACCCCGATGGTCTTCAA
+
#;D!G!4B)',!A=!ED)#,5:@-8">>;!;>?"HC>8+HD0B4*"E!*C:6+2!
@r2946
CGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGG
+
>;/--!26*$E4,F&C)'46G(G$&7&.-A'G:(!#6A)@86('=2)E*8@-3240A?8(1*))*E<%"$2
@r2947
GCTGTGTGNCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCANTTTTCAGGAAGCCCGCAGTGCCTGGG
+
HCBE0*<DCAE?D25CD"!6:@!@=.#@5GH$?+47&3EF52B$&:+:,?CG(04+%,/-:"77(';&8=75A&+6?;=?6A&('/1<B/+(;F=@");9>,&7<+9F1D69'*52F7)@'/B"*)9*HG0--)E(4*,&<9FG&&DB7*;.3#(C-E#&6:A4/2:2"%C5>DHA-:(>1&@H.1&G6<#H1E'#,::D,?5(E-/"?!(2@D*F#*+*@.H0DF3F"0FF-
@r2948
CTTGNTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGA
+
;<!0@A?B2GC3F)"4/>?D(:(D!>+$"(GC44CG/.4!F<,7$510,4C43#E2:A(%,'/,
@r2949
ATGAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATC
+
#%*+&$"%!&*+#')+*'#$#()#+'(("'&"$'!'(*#)(**#%!"&&)&!*'%!!')$
@r2950
TTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGNAATATCCATTGTTTCTTA
+
*'&#'+''"(($*'(&#'***""(')(%#")+$$+!'*!'(*&)++&$&"*'"(%!!+&""'#*%(#"$'('"%''*$+&&'&)+&+'$
@r2951
AGCCGTTATTGCGTACCNGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACTTT
+
D$"9C.76,*<A$1.;;<<907@B3!=$7;GC1&H%%9E1!-7(<5+:D1G<%7)H*GE?.&4D3'C*7+8A/09*,#
@r2952
TAGCGCCGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGANGTGGTTNTGCCCTTAAAGGTGATGTCTTTTTCCGTCACC
+
#!)'04?(%F,@(>B<8:B+9<:!?F;F'56"E@>=58CG9-8(H7==E;5?E3&>H%0#-&"/@3(+F;-%,61?53+2#7%$G+C
@r2953
GAANACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAG
+
)&+''*+%++%$(*'*#*('!+*##!$#'((!)#%*$&#$$!($*'&!*%'+'(!!+')((+*'))''&*$#"++!)&$%%$('###$#&)#*)&'((*#"&*$+*$$))&)*(+##"&+!')'"*)*(')+("$%'!(!'(+
@r2954
TAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTTGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTATCATTTCCGATATCGCT
+
(1%7&:0(<!#&9#&39+97+?A!.)7<&>B0AG'3&B3D/61>=&6*C"@HA-3-H%:+FC4)4C,22#F$:<798A@$CH.C!#)-#->)D05/1.;391G*B3$3+!1168-&$><9%7@G2GH?5*5<'$B5$G!+4#)0?,D?,4H#@0(F>))880D!41,.D3C(.#<%$&#$7$-=<<A59/H239A8C9$%=5*;?8D*+1H#<F@?)21E)*>;)":@&%9'C4=F'0.C:AC7G&;4&%!),>@D8-B!3,;%2E(GD5-E):4/;#%$7&=+2G21%H!&9&0+9.F0C8/>77+4H%+B&+4G<2/'><467+/2C%?'G.+193B#8G7AC?5*2*@-#;E&49BE90H%>-FF(:.0F%?!/9
@r2955
AGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCGTTGCCTCACGATCGCCCCCAAAAC
+
-</)6"?15:5B0?E<,"1+31%*+*3+=-#7%4@.:F4!0.8;%6)#<<1/<9"6*."6BF<*+*C?ECH"2+*&(&!.9F<09,%0=#E>/G$)'6;@-'#;GB,4G,(-,!-(-@7/2A17<7#@"%>GCBFA5#3F7#="D<>$&D;&#E6/5>:4#3
@r2956
CCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGTCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAACTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCG
+
(*B)F1)"'41:59?;=&*8%733;!A4!H7)4G&-(&A75;=*;54FEF52-++BH2A4***=,?.%5'@;*,)4#*?D"FBFC%<:GA3;$)*H54:1?F26)G6C#)$",#F6G?/..1%<G<#8G23(1D)3(E!C0:00H%/3H'C&(72??C/BD,2(+153EFH*DG@#CED5:3E?!==+?'$#;>7D<$F)CB:?:A0*17E*H;%@/<A53-230)="B;'H34F?5:0*3C=+4$:'6/:06??7(2'C5-#D?/$'!B$#EC@$!/4-A5.F#7-G>D3>:.BFE;$739.!;=H%G/E2>HCF52G?6%
@r2957
CCTCACGATCGCCCCCAAAACACATAACCAATNGTATTTATTGAAANATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAA
+
.*=38:,)C!63=681!&'4(/G;!(B/007-#G"5"/8D(/))<+8>A8/%-E=C02)-08%=6!G'D!C!8*4.2"F-BH#*1->(-@.>$23%/H70!!7;*H#/@8(=A,(BFFHG%@*1@4..&<*?+*
@r2958
GTCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTG
+
"F')H>'!BA(G425>.4C;7@-8@97"E=348!>&4",32%B)8DA!G&A2.,*8@=6?838C3
@r2959
CCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCG
+
,=D>2#!DD7(==4</($D#*!7;3)>F?-)A(28GA71D67166,2;28
@r2960
ANAGACTGGNTTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGGACAGCAGGTAGCGCAGATCATCAACGGTGTGT
+
%!+!#+&%$"'+'!"$+&('(&"''")')*$'+)&+*'($$$*%$'$""!"*%'$#'**((!#$*"'&)#%'#$!+"+$)!)'&#(&!!%%"*$&%&%("(&#'$'&%($#$*')$+%#$'((%'(&"+"&+(+###))#+#)&"%!(()(%"(*(
@r2961
CGCCGACACGTTATGNAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTAAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGGCAGGACCAGCATACGATCTGCCGTCAGT
+
8>@9F2?,5A)A!#6=9$E*.G+!2559;8;&D.8F6&>&8BG5<A4#E-2.#AG<0/;&B6"@C556,B&3F4=0BF<7'E*.-B:-F-@!=BEG'3&.CB*D$,C!"$"/#-,@2C86B9-5@8$>=C9.."F#4,@:4:?/C.@AB%?9&40.H/#"0/>7@,"B4(+(.B&?,A$(&C#"?*ED2:+'6G>>D!:$>!&4F*+G$3=-+>G$=2A$39728#>(=BH00'4*;37<:>*5)*:+6)()(;<@?<!*94/&@HD)
@r2962
TGCGTGGCTGCACTTTTTACCTGCGACATANTGTCCGTGGCGCTCTNTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGCTGTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTC
+
3:H"@38''#(C;E)B2&@>&#)0B6/H;!')AC9,;B.9;9A0H)(+);C,'903#$@!.>+=B4*+(CB7"<G>$5-4FB5;8$)>?5(H?9?85&<1(&$>(%<::.!,E'5.@%;(&704"9CD"@82C5F+4@<8CD'E=5#1EC;,$;7=#/<';3-%BG>(7$.*02&6/(>G7749B@3B43"63D9("G(&G27GH3=+<-<<<C>>+>.!<009'6FD'C&9'*B0-A;DFC<5-54$$$7.H*3(HFA:0E9=2&7C,='D>E--79"1(@@*!"$>.!8,0*?'%C"GEA;0H="G744H.*C$+
@r2963
AAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACA
+
/.1=D69D%2C,$E-&130G@H$6*@G9?>;C!AF,D#E&7*!6E"E;D70B=1E1GC)GHF(E#E3G47,$-4
@r2964
NGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTA
+
-38),)B/,>H27,CG/C;3"A4(7A-;1C*C2%14!D=5/F=9<<B<;G*9D-*8?G074E3H/>#:>1(0?960,G$!C
@r2965
GCNNNCGATATAGCTTCAGCTGTCGCGCTTGAGNATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAAACGNTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGG
+
%*#!)$+$+!!#$%"$"%%&*%&(*$'!)$$$%""!#'%++'#$(+(&")%'&*"(+$)!#"#$)"%)#&!%"+&(&*"&++'!(#$('++*+''+')&&((+##*"##&*'+$!'"(((+)*!+"'+#)$'&("'
@r2966
GTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTNGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGAC
+
>"&GG>9?0.&:>=4$:5@;+$421/?8AEG%7'*=A%,4?E-%@7$A%B.429G#B$:1.B'%/A86;>:,'2+>F7;@HH(C'6=/"94870(:E+/C))*<H7"A+H:A/$+@28FGG&2%.EH7.)9!0836(?G<A"3A0>;;@+C4)4"/6D=G7@'$GG294F?4*9!+E($8!.':9>=E%B05=*"""G3=#0</G@3@02;0&;0$CC+ECG-;"755A#
@r2967
GTGGTTTGATGGCCTCCACGCACGTTGTGATATGTNGATG
+
07=##@FH<'48@%&$E,+F4-B5$"%@+;-523@="?26
@r2968
GAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGANGTCAGGGTGATGG
+
?7/9?/</,,(.24<D?-'B3,)44'<E%)1E&F(G2->8G>,4H%"1,!6+".(D+5@EA()C8%5?"B2B<65>?)"A'1;':##A*$-@(/A%0C@+-H?/*=04><??./F8F
@r2969
CTCCTTATTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCA
+
11/F0.C?C.?5/54!CB6B+*+%#*C61$;1"?C5G71A=16F@;,
@r2970
GTNGCATAGCCGCGCATCAGCCGGTAAAGATTNCCCACGCCAATCCGGCTGGTT
+
)$$(++!$$!'$&"&#'')((*'"")$%((+''"$%(#(!%**($*#"++*%&!
@r2971
CCAGACGCGACCAGTCAACGTCTGAAAGCGGATTNGCGTAAGG
+
1#"G/DC>A)G14D4!""*<#/EC#2A.G5@;;D%,B7-2*6'
@r2972
AACACAAGAGCAGCTTGANGACGCACGTCGCCTTAAAGCAATTTA
+
H0G:/(C(B/;-%*13@B4)B+31>C=.D713)73+D:.$7;<49
@r2973
AATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAA
+
(2,)*;.#E*C90&.%-)E0+0:G,!?(H9:?C;?1(E#6;%+(,?4".?6-@*''<<?6B<;6$90><*?>3HB6*>.&)5,:*.8",E3+81=:07')?F6);!@/C<D2E6+,?6FD=@$5!F2#')&H/72);".!=';0H-<!+5)8?@+"C",4>F=/57*>92@.@)H=(<3)>>0F+07!&7<:2<4*<51A,D4*H4>330
@r2974
NGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATC
+
%#A:>&;6&D.$4BA?&(/>D0FG=2!6B>6-H=C8#BAD"34;'(-;
@r2975
GATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGC
+
'G9D-B5&=*=#.:=!<,06HBH@D'3.$/;=.+/@#!$B??<
@r2976
GATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCT
+
,&*;$DA$:.>B*1*'!2G79H?$58H(/>A1,B@,0D=?';1@A,'!F,5HC
@r2977
TGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCATGTCTTTAACTTTTGCCAGACGCGACCA
+
+#.'6A,&"(#H;',D91=C((-/#D(-DED6(BH;>GG79,@;,C@E3-+8#+2!%4HG1'F;$H-
@r2978
NNGCAATAGNTCTGAATNNACNNTNACANTCGGTGGGTTCCACGACCGCAACTGCCCTNCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCAT
+
%"*'**'(&&!&*(&'(#!(*&&(!!#)%+**#!$!#*%#!)$"+"%!)!&)+*"*+***($+$'$&('*$'*+''%'*&'''))"$+***$$&#!#)%)%+)+#$*($(($$%+)+&!)&'&&#'"$+&&(*"+*+++)#"*&*"$)'&'%(&!#&$#)!)+$&%#!)%$&)"**#"(&%%#*+**#)#(
@r2979
GGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTC
+
,3(+>H=D=-E1*21'<2F,G)(3"=;3=/8:0?=!=.A+BE3D;37<.65,+9((!H(-+361"#D?*,
@r2980
ATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGGAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACNGCTGGGAGANGGCGACAGAGCTTGTTGAAGATACGCAGGCCANTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGC
+
A(;-73.,:H=A+D,27+C'6D95%(A=!<A+'C=C;BA+/9F;<&,+&:?B@?&C)(>D8/5101*8%)C#.A;-;H%@A+8'#HC/B.;:B<6+1:)?@*G"'43A-0F$26B+9<3FE3!)/*H,5/,*D&AF66,/DBE!8)::BF8=(@D:7.@7-7C($":!H:<%;31,+4>
@r2981
AACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTC
+
/CG6;&@?AB2//(&E?AB<<0'/3@H3,85<DB4%&C3/$$(-"9@'8,+H.
@r2982
CTGGCGTGCTNGCAGGAAGAGGATGGTGCAGCAACNAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCG
+
"("*%(("%#$#+'!+$%$&&#)&)&&#%'($#*!$+&+'*%(%+!($%!%!'&*$&#&*%'$('*(+!&+'&"#*
@r2983
AGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTNTGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGGTAAATATTAGAAATAATTTCATTACNCACTTCCCCACTTTTTTGCAGAAAGNACANCAAT
+
.(>6A?G.&<1-:2/.(17$=:398C<8#<1B)39;*C16G+E"*>.?-,?!((4?*;-,9CG$%9.+05H#0.+>A5+3:""D?B2#==D4H;>B#-5>"A1A'6=4&&-6F4H2(H?=#->3B;08"3#<04,1.:C"0%E48:%F3/9AH7:F>F5DD25;G0=/?&30/:,-61.(#8'/!%#"BG-E&'$C$!1>.FHE3(5A,@,@F5/8-B>.+5G33CH;3),6/83BD5+'@?H,;9:<(#+,"+"6"<'D(D0;3!%)-4HA.29/6G#D$0-3D>.),%,BG?/35+H(F<A13"'*C*/F+&>11D&-?G5(70+!0(BEG;=,AF;D"/7AE>*+,B7'/0C>="G=8!:;4?>?AA
@r2984
TTAAAGCNCCGCAGTTACTGGATTAAGCAAGCCCAACAAGCCGTAAACGCCTTC
+
G@#./0;*(%DD=$*##E4$87;$1@G*?</@C3%A'D(%"1:63-%<%B03!"
@r2985
GGAACTTATGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGT
+
4/7%E6243+B!9A?3"F90=,6&5,;?9!78845BE%CC')-+65G(E<"3D8,:5C4=F-<@=+99%)B(G&;!8&,):*!%"5;;2C,6G$7!;-4CD*B0C*6A
@r2986
ACCGTTGTTCGGCCGATGAAATGCATATGCATAANATCGTCTTTGGTGGTTCCCCTCATCAGTGTCTCNATCTGC
+
$++$''((#"$!)#+''*))%$#+$"#"!$%+"*"%)&#&!%))!((#*)!+)$"!++%!$'!($&+%&#*"$$'
@r2987
CTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGAAGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAG
+
)H@-*B*@<BF0/'C&0D('&A9?+CG-8)*"+(B@?+8-6.*G&<9-%G2&A+9+!0)D'16!'C>&DD*1/"C(GCH3%8F:A#4554$"(+#<;G:;-+;-F0*;5<>76,DD4>B,-(#"DG03'@;#?>69"=0B2"(2;9F).C(<-:DC
@r2988
TGCGGAACNCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACC
+
D%>63+$*&F3"((H786&ADD9G4E7G'H2$(7*%1BF2(B%C:>E-H!&7E@-2%&E3G"
@r2989
TTAGCGTTAACTGCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTC
+
G#H<A6A*69;A@80(C9/;='%BF5F.";6@;27)87>>$2;#A@%?*/E4@6;17<:B)!/;E.A,'DH84$:54+A%;)6''/.76)36E*-$717=B*G<&E&>"!<274+B5@4*?'?@&C<&1?0;&%+'2)2'F=8+.%'&$"/,!<E0='-/;;)E+.9CB0,/53"-
@r2990
ACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGACCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGC
+
<3,!&1=!1(%B;HG0%3@E>B;@4'=!0$%&#>H*+?A.B@@$8$+80'8D/,CD,2/634A"D"E'*=,*D93BB%F#&<36EH,.$=2EA==D>*1,A14&($3
@r2991
CTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCA
+
G>*3(81.&E#(>F+/(7;1A1*=1DBC%16*F"2*;.@6
@r2992
AATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACNGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAA
+
)A5CB'2C%5CBE3+D<0G?C0A%D7?";0!?6DG)E5<#6!%'8*5C30.)3/C)#>?4,@F8=H0#0=5%@%F=:!H36+F<#%5#?.B.55/$A%723B63?A;D>*-,4H#?"C!:AF*&:=BA.F-4.?<5@@
@r2993
CGGAGTTGCNGATGNGTCAGNGTGATGTTGCTGCGCTCGATGCAAAATACACAAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGNGATTATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAG
+
'"%)'()'(#'%"+$&(('''(!#*'""*#('!!(+%('"!#()*+)!))($($'&$*&&*($##$'$&")"+((()$%(!(#%%))#$%))&'')&)%%##%#!!&((#$%%!&!"(!+(((#%+!%#)'!#)###"#(&+&!%"((+%&#+)'$))+
@r2994
CCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGANACTCAATCAACNACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGA
+
231).=#;*C520."?)0@''?5H697*FHGF6;5A';+@9F(G69D01;*C%>B!6"&,#9=35B;G,:.:6)3?@4:;2?@*.4.-7+C+?.0#.#D,H$(?=D-!$;A7'-+
@r2995
NTACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTNTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCA
+
!+$F,>CC#?,1,@9/-A;&689+:&:*?HH6/6(B7(&;#2?:#&B4"?'>>9#2."H<'0&A%92C@>$@A6CC'.0C,!9"8+
@r2996
GTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACANTTCGTCGATGGGTTCGG
+
H'93;1G<%BABF/.2A<.!3H<-(D-AD1$4.-$>'3&5?%./80$$4&24;3E;FA
@r2997
TACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTCCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGG
+
A$@2B=;-1)==B,!!(.)3)>11-D-E2&B$5%F04@/-81)E!D)<3-',HG<#F#GE813A#12'@7?>$,A2F.!./<*H-B!'3HG@B1-';=-(G>9#>G3""67<E6."!9%/6=11+-0@@F%5,DE0HF<;;$14.45D'?09G*H#A/D3>8?G,C71;!*B)5&09!!F@%!,.6!
@r2998
AAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAA
+
H00:%363E%@,)0=-A:@G8H7<0.,!F45+'>92GB/)'G=:&!9-A34#,/";H(?,,FB#,*21"$*%):-++1"3$%"H
@r2999
GNNNCNAAANTCCTTTTTNAAAGGACGGTTATCACATTCAAACATTAATTTTTTA
+
%'#!%!&&%$"+(('&"+!*"!%"!&)&&*"#*'%&&))%)#!*)+%)'"!''+)
@r3000
ATCAATTTGTTGCAANGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCC
+
9:F7?*>1.3;:8H96$%B#?4*2?F=5/@)-67"A3&&'G*9C!=D<#B)32#H(DHD"8'G3&9?3%D*AE"A;:#$@'4?,*"'99FC.)"(2;>/%;CG!0/H+9'$5/E743E:;A%$C
@r3001
CGTCCACGCAGGCTCTCATAGTGAAACGTATNCTCCCCGG
+
92A?A(%5$$2&B8=D!F@A"+F!:@0%$-#(;/&6GA8B
@r3002
AAGCGCGNTTCAGTTTTCAGGAAGCCCGNAGTGCCTGGGGGAACTGCGACTGGATAGGCCCC
+
"@B'')6.%"G@62&&>*9>9$1F,<5,#,$,7(G@CE>&;16?2+2=;<=%050D4&+/HF
@r3003
NGATTCAGATGATATGACTATCAAGGCCGCCTGAGNGCGGTTTTATCGC
+
(F(,;(F;=08-A88GC>4)8$<G2?#)31;%4*)&E.+&!EG.'7,9@
@r3004
CAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGNGGCTTGTTTGGNCCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGA
+
+**+(((!"#'!+!!'&"!&%&*("**#*+$(%)#(*"$"+%)"*')'!++!%("+!%*'!!'!%)")$*&%!'+&'(&"#'$!##+!#%"+#""%"''*(!%+!""+#!)$+$&%&%*("'*+(
@r3005
AGNGTTANTTCNNAANGNANCANNNNCNTACTAACATNNGAT
+
#!#$"$#"!$#!""""$$#!#""!"##!"!""$$"$#$!$#!
@r3006
CANTNNGTCNGTATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCT
+
&("!!(!%$'%$&$(!"'*#)')&(&'#"+"($!"**%#'&&$)+"'&%*"%*#$$*+'*!'#*+$%#'#+('*)%+!#'$#'!&+"%+
@r3007
GTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGNTANTGTTGCGCCTATTANCGCGGCAACGTCC
+
%2%0@E==.>#6/)995<'!CG.:E0>%A)E$&49$9G=0,<;7A1@<39=&?#0B"?'-01B+8$=
@r3008
AATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGG
+
*D"F/.8!>1+872FD-C+(G&A+G)(AG=6&<)6D@')@#G#1:G
@r3009
NNCGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCT
+
&#=0C,/'.9;/B)=6!+5#$HD:F'-!C!?C;<)->6.DFF.57H*>9#=:#A#(B0
@r3010
TCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCAAGGCGATGCCGTT
+
'BE9H9;2(#@H76==7!#;B+H6=+5=D)+7$5,$D2G04@.;;!;,5!)90F#)&?<-";49@---&?DE-7*7B)2=&A027B8@+,9'*08H(+>"?=?G;G@)#&/*B)'4F,;7=F?!,6+:G78FD
@r3011
NAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAANCTCACCCTGCATTTCTGCCTGCAGCCA
+
"#7=>!.1"&2F6&7/&:77@FC82(!930'5=8D1/F&3?+*0>&/)C):&-G=<+?G:DA=:F?94&G+%
@r3012
GGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCNCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTG
+
03%(',H/7A9H>025D.(47AC(<A2+3577#?+#/H%0A@/C5(>68A78D5$?183&FHF>A!<=1+F<BD*1")/20'-=.8G)A@6F2/3B$0:@A=&;*=,,4.0F>D)7')9-=0>%*E.8@*1"3/H"G<.8<6#""/*!F".,76#C'"1(9*/F#@1-
@r3013
NCANAANNNTCAGCCGCCACGTNTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGC
+
&)'!'&"$#++#(#(!#%)+)*('')$#())()$!*$%"*+))+*)*#'#%"%+")'*!!)'!$'&')
@r3014
TGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATNCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGA
+
(-6C&%+724A038AA/FE':@"&"BDBG.9.AHAHE<,HG+F)($6*!G-24@C%F/'"E.8?HA;49;:#:,+F6.>-A2>)GDD%'%8=;';
@r3015
CAACGGCATCCANGAAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCA
+
H1?A143EC3;/3&:F/B/"9=E.$DC8E6C%?=A&'?>!!85%2@E#54
@r3016
CTGTTGGTTAATACGCTTGAGGGTGAATGNGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATC
+
<>3-!:5%58#8?5/@G52+!%=$&@791ADD"@<F/(H-4(@#-?;@E):.<<@)=:2'&=2)+)D"FF1CB.@#>%&!$:G<2
@r3017
TAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGANCAAACAACTTGTATTNCA
+
$,2HG,?6'D%(107%#??B42B+#B1-?/@C+)E7(;22-G1;2-9="H<=0<-D/4E
@r3018
CAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGNGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTG
+
9#@#'#13580;@%6+5=-+,=G=<D+)E3#+G#213'.+&':5G=E.1!./C1<;A#DD;4%BH<3+/2#E(:C?3.:+=@E@)*%6AB794*D$17(+;@20"(>:*A$F1&*;;((B6):#9@6/),2/02%$(0,A-)3--#<2C,G+A9?4/1.):AG5279?*1%%E+3$(@%$23C-=/0737+-G='F3$6,4/B;CCA9&:%"'H'0G
@r3019
GCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCG
+
*HG%/,.G%:?'',%6FC#FA$FH#7,D,<=<FC:A,(=!F
@r3020
AATAATGCCCCTGAACAGACAGAGGACCCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTT
+
F?1F15-$)$E-$#6G,HD6)CH"#3)$F#C(4A.<><#-B;0.%>"<#BA5/6#E+8$#?;F!$.3@&7'E>79%1+&D!;9>=>11B0B5/!7D#9!",&6*5+7!E!"2)E8=F1.'(F/+E<9B7!4096".2*@G0/6>7$.2.)&B(H6C*4#;5@?,@6*0:%.,$%).*@G*3G#=''(EHF2E=?
@r3021
CNNCGANAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGANGAACGGAAACG
+
'!()''&+)&)%&#%"$!!$'("*$$'*!''$)!!#!%(')&&%)$*%)("+*%"+%))$)))*##"*(!)#&+$*"$')(((%#$'(!&+%$&((%)!&*&$*#*!'('!*$#*%'%*'#$*(!)&%")'*+&**+%'"$#&)*(%()##)"$$+%(+'"(&!!$##"*##"')*%'
@r3022
TTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACC
+
87H327;C65'AG*D<!#/:B?DG.HC,1387-.E?F/)=3"(B126!
@r3023
NGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCT
+
#*6=,#+H7B2;4#/4/@'9.:-5H?B<#H?(5582#D;E!/6!<&H>"F4/%2*895)%%4)+;D?(H-;,+3/
@r3024
GAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGGGGGTATTGGCCTCAG
+
A8+DGAH0#H,5@AA3A*'D.;1E56#?@5@G28B#)B4&(>!E)3',&<C>#=5EGE:)G!(;5:D7"/#@1/=>HB!+1<C85.+6(@0,,
@r3025
TTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCNGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAG
+
?0@273!25%#!B;.=C'+-6F&&8%."3,46$;3&17@1F7-@H-'E(-6"E(G&C!2#D'5G&3<B""B<DAH9)C;HGEF2>'/73:9)1&3<&,:5)0C#5(BH4<G
@r3026
CCTACGGGNNNAAGATGNGNCCNGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTNAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTA
+
*')#$*%&!&"!&'()'"&$&%"+&$+'!')$%#"!$&!**&!(&#(+'%$%)%()')$&+%$$+'!!'*"%$$%()%'&$&!+(&()$'))"((+$)#%(!#"$!&)$+""%+&&**+*"+!!#'$('*$(('!*!"'""+%"*($!($#%+(%$($%"&'("*&"%#+()$**+%!#!*$*"%$(+*
@r3027
CNNNGATGCCCAGCGCCTGTTTCTTAATCACCAGAACCTGCACATCGCTGG
+
#!("(+*'"&)#$!%!#%+$#+")))#%%()#$*'$+(#"+'!"&$#(%)'
@r3028
NCCTGTTAANNNNNGANAGCGGATTCGCGTAAGGGTCTCCGCTCCC
+
#)(#)'#))("!"%#&!'$)+%"!!)#'%'+&!+*'!!%++"!"%!
@r3029
GAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCC
+
*26!;H199<HA#&A5(?-.93A52.F:%C1<,H?>$'=A.'BA3<<<
@r3030
NATGCNNATTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACGTCCCTCTCCCC
+
!#&#&'*&$*+&)*"(!&(&('$#'&*#"%#!(!$%($%"+*+*(%$'$%$)+%$(#"+!''!)(%'**'!%!""*&("+##!"$)*(%$!%$"($'*&+)+#"%(!*((*&&&%(!#**"+"
@r3031
CTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAATGTTTTT
+
61B3+8B747<0F;'?<=$4F;@:3;AB!"*(6A.$+/%F9338A9#>/C+B)C70$.D(
@r3032
TCATTGATTCAGCATCAGAAATAGAAGAATTCCAGCGCAACACAGCAATAAAAATGCGNCGCCTGAACCACCAGGCTATANCTGCCACTCATTGTTGTGAGTGTGGC
+
'+%'&(&%((#+"%)!"%!$!""+(+%!"+"$&''!))!)%&*"%(*#&)#+!*&*$)*$*%&&&&$)#**&++&$%""(#)$##%&"&%()($#)''*+(#&*!%&
@r3033
GAATGGTTTTNACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCG
+
?8-95#5==!D4*1%E?15)>(6B%<%8>1B0A<)$EH2C'F$@5&<3
@r3034
ANAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCATCGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTNATTCGAAGCAGATATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGCCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTATAAATGAGGCTGATGAGTTCCATA
+
($G3367'25)C*:A*?,H7'0#)".=F9+=E&0*HD")3A39+72111(A>F&F-AG<'D18E%!/!5.G*CB"#0=;"3D0*B<!F@0FH=3B;HB;>2>9C%$F<0@:)8B3(4,;,*.2%?#?-&9>5+80F+=A!9>/!&60%)F;="E+++7:0D.,H4):!.",FF"BB!!<)8!%6A/?(8.04<;+A;F*#.73<)0;EC:E845-D$>;A220/B:E$)EH2F17((<#C93')8$E%:9*
@r3035
CTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAG
+
'G">D#:4'D9F6)&D$+?:.=9=(3')H!G/1:+A&@.9%A0;*#6-F-:A%3GE%,>!E8GC@@@'$AH9'H;HH-))2@;#92$/:<8,D>6$-B-1"<74@+46$,%9)6$$>2@G@HD/E+#1)G-<;-6'<.0=((*F/;4)G*0;/2,5-,17:#432A*E+?.DA#ED>)@!-3AA2?/9"/>=E=$$;:786"E:'*=
@r3036
ATTACGACAAGGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCAN
+
/3G;!E$2B*8C=?HA,A$"D:7''0;0*@H.6>-96+."C/<9>B9))3G-7A%6+$2)2(A&-:;G.E?-5>#37>&++''91)*8+H##C6!=@6?,#9!.)"#/=;.3;:6F07'/."%C217D!"C+63):1(B#4F,)$1ED7C97C).?F&-E;2D1'7"&5F$FEEFF04;H,?/B+
@r3037
TTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCC
+
C&!=74EF417HH3$62B?=A%<>>)9'$*%(%F-F&*:.0;'3,-2=$02*B
@r3038
GCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGC
+
9G9E>C9;AHD,3'-$"!D!?-+#4(71$1='?1??*H3-)AB,E(&2!E)-6<GG-898+-DA:;7;36*.#"E63*E"!(@(::@29$0:,36=/?!>B14.#80)52CEGH%89'!A:F@@G?'.E<,$.?(;/H*+".;;H>6=760?'D/:14@F(175*&AF%=!D8$1A.)=;86)!(>;F-+/2%2;+F3C@"$B"(:'5;<'8A44!"?>G"4#F&.H8?@6!502>849CC?#3.3!G#0FC;;'(=1!&<==#@)*1+47<),%0>0<AD>0*>F66H8"F&4)';)8&"21@!(D32"62,.,F#9>F?6<
@r3039
CCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGT
+
4;"!)20#E6,<1.873*A112&08:+G+<4!3#0/(/',56-B=</&D/-0-06*406:FAGE4/D#@2
@r3040
ATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGAT
+
A#=G@6B=B@3;64395CC83)-CF+'A&>?.AA(4./*$5<#D2,4=.4?)4.#)5'
@r3041
AATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCC
+
2D:.($#+4GF>A!0*@E5@E1F8*-,02:81=HA8#:58"9';>85E&5)1@8#2=E:6&&4'>&209!':9:7
@r3042
TTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGN
+
C),=8;GF+48B>,/-*D61-41:10!@C#39E(!-;1#9;H:<%H
@r3043
GCTCTNCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTNCGTTATCAGNTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGGAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCGGATAAACACGCTCGTTATATAAGCGAG
+
00#$!,E!'6"0!.C;&778$(6+@.:D&1(:)>D73'%-+#37F=+GGED/.4G/.%()E/DH4,A5/)3"+8(#3&-:FH*?H?G#-B=G0G5,#G2)89*%B(!C;4H<7&>$909,A9>8&G/0);2F*F::,&<./:6&?1BF-F%=9A0.:B8.05@$.2;AA!GD956?@AB($'G@A*A3!"0C4:;?F2>41649"?7/C#2?D1AB>2
@r3044
CGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTAC
+
>)+#F1C()>1%5BEG#1$E-8B18@001$-/(G:<'F$0<4)7
@r3045
TTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGANATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGT
+
(((+)&(#'+!"#%$&&+'('++"*#'(*"%%%%#+()$)#++*$*"$%$$&(*"*&##')#*%+*"%!$)!)'%*#'((&'$+'%+"((("(&"('*!*+#**+%#"$!'%())**)$)*#%+**+(&"'
@r3046
CATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATAAAGGTTGGTAACCAGCCAGTNGTG
+
?:67>3ADF!"/%!5*%G#.H*247.2?6G*D29409.<9,>F'0*.(F/#$?A@)<-(:'A7?GD+7)%D1EC&$6@@#;F<H,
@r3047
AAACGGNGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGNGGGCCCGGCGTCCTCTG
+
&(!(!*!*()*+#($!''(#("()&)+$(%'*%"&''$*(&'#&'%(!%"!++'**#(+$"#'&&%"($"+$%!'!"!&*(!'*++*!*#+(!#*'+"(%+)
@r3048
NTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGTCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGAT
+
*<2*0.!:1.H4G.+H&:/=B5C#F&"BB<?:$FB"(H2$A5'1>%!&6*)"D$%6*-#;;C#+E92>62&G1)$.D1-$&E=H#?A@*$77"('>>2.=,(9"A9&$'4/2'='B*">!FG'+ED:D")AB
@r3049
TNTNCTNACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCT
+
'!'!#(!+*('((")")(*+%+%+)$+%**!')')%()&$#($(
@r3050
ACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTNAGCGTGGAGGTTCAGTCCGTCACCGACGGNGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCACGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCA
+
=.0).G29623A,G-F0.4:-<?,ACE5$"2F'"$82)--5C,)G:B@3HE8%HD<3/7:*5C.%D='.H?DG&(>::8#*'D(!6(<$:H$!("B*>#<&2<%H:429';/D<!>5GC'D%-F5!3&&+@"AHBF/"D93H<2<<(*#3D4>E+.$HH=!-@E#E=#E(A=%8/=/G0"(C/F!,2&1+-F-1-/0'!H1,)*8;+.5(F7F9@8)D4);+B+B7?@;74*1)4'(C:,!&-79#F;A--%0+B0:.)E*+/>B8!.9+0'#F!B75<5A900*G#=-'1H5:&4(C78(#%!0-/.*;,>>-(15
@r3051
ACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGA
+
C)B$+*FG@4/1<+H+6D$8@7!:$97@?&CAB<?>(07F!-.*01@E<+'DH(647),5(!&:)5B1@;->E%8G5,44?2AFE?(
@r3052
NCCCCTTCCGGCGTAGTGTGAAGCGGTTATAANTCTGCTCTTTCGCGG
+
(*(+&&+('&%$'*(+(!)*#(')'"'%!(%+#'"&*)!*!!!'("!#
@r3053
AGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATTACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTAT
+
)'H&*F6G);,DCG58F8*G6(*A=7:D26A;G;@=.?E7C/"@*7!;13+(6AD011&2?(">*.27"-9:6/-%E9?.4C4;&1!FF!?74";""C('##@'F"$82(!9>2,/9@</=C21?G/6=C!<&B25C%4B(F@#$57&:(G<D3A8<&"43%@8+D&%?%:B(=%&#$6%12D'9@>/(/<5""+'F'B*4),$!9D#;%$+->9!57?!=**,,(.-)8+=$$G051*3)$"<"7@)?
@r3054
AACGTTCGCCGCCTGCAATGCCCCGGCTTCATCGTCGGAACGCTGCAACTGAGCAACNTACGCAATCTGCTCCGCCGACACGTTATGNAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTC
+
"!++!*)!*+&"$'+$))**#'&"(%!()($%*!+&$%#+##')$('+)$")$&$*&!'((*"&'!!%!$)#$#*)#%#)"&)#'$*!"("%'&&($*'*&$*#$*!+$"$%#)!"!!"#*'&&+*&))&"'#
@r3055
GTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGAC
+
3G%:%76--9))F60-4="2<F:#(,$9(;D*#13@9=B5?';'8F&)FEF8A"(=:*!,"4$+&'-AG=A-+>(8#'C,>"C35')CF,,&F>02'$<&&<&E16</!,&
@r3056
ATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACNTGCAGACGTAACCANTATTCGAATTGAAGAACTGAA
+
HF%!E+)!6*8!4!C&-1#*<86,G!)@%(->1+,:H,@4H55-:40,>EF58.!%ED7)/?"1)==D</4@.6$)<(8H0<"AHHA,H353.=B$,/
@r3057
AATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTNTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGC
+
,:;G0D?87A!A*>1C$98%<,+@9D%@FAB1+&=#.G=6@@&5?$7515BBA&GG+0DE)!%E8G#6D1;".>?3.H1H:,>DAH,%9>E>./8GG!3#)*8AG>4)+@D-$C80?>
@r3058
CCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTNTCAAGGCCGCCTGAGTGCGGTTTTA
+
=4'*-.(D@5D%9&):5"0<G2&,82H@("C+"8>.*88+@;*.'3<@/':F3?&C/0*!?28+.,!1-'
@r3059
CAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTAAANCAATATCAACCTGGTGGTGAGCAATNGTTTC
+
?96'E.C(7//%,')1@/-';%C%%0E8;@6H@H)$@3,G+-"C26H>#2&%"7@G*1";/C7D.?0/A.%#'7!*0D
@r3060
CAGTGAGCAGAACTNGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGAGAGAAATTCTGCTTAAGCNGGCAATGGTGGGGATTGT
+
**%+%$#!$*""%'#&"%"$($'*'!'*"%(&%!")%'+*'*%(("%%'("++**$#!+)$%+&!''&)(&+)(+&##!(#*!&"%+
@r3061
ATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACNTGAGTGGTTTCACTGCTGGCGTANGACCAAAGATGAACGTGTCCGCG
+
?C>G@86)@8->.A*+%65A"EE1?'>9%4EF/05!2G(?F*7!+':749"+%$'%3'9G)%#+&3*#!?H>6G<1;'7%.C5F!5F=:3&<-+3*199</>;98G(:.&D87<?/<4G6"5=2),5H?>?
@r3062
NGCGAGATGGGGAGACACGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGNAAAAGCGACGGGCAGGTAAAGTCGTGCATTACGTTTTCATGGATACAGGTTGT
+
&D$%10;8#+'G.C?&7F!3B3/E+.<+:1D1+&F9=%"3*@4./G8%&9;0=HC.9)F,@DG$52B1D88%/CB=5A)A;%7E>7!/E5$'=@9.(/@5,5C##?4!GFC?4",1GD4!B-%-.FF<B">6+08A0+1)H
@r3063
TTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTA
+
6-,"E9,96+(70!4C99,,F5&-1'?F$2GF0$#:G-"G(=C;.;/GD>2A-;F%*$.BDB#!.*C0
@r3064
AAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAA
+
>>8F5*=9-&+B?%!4F+5E%14:<;!?C&F6:AF?E>3F'@*@0##!H26D=06#/B0"6:5+:CB$=%2H=BH2:)%B
@r3065
TGCAAGGATGCCAGCAAGCNCAGCATATCGCGTTGTGACGATGCTAGGGATNCCAAACCT
+
,()E'@".$!1,4;F"@H8@605.9"H%/'E%F/7=38=24,F$>4%'*E*.H,:#6E.9
@r3066
AGNTTNAACCTCAAGCCAGAATGNAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCT
+
)'!)$%+&+!")$+&(+"&*%'*#($!"*&'!(&'"(()"!&$")')**%*')")%$))#%#!#!"""%))*!%+#*!#)"'%+'*&+!#"$&$!)('+"#($&((!+(%*'+
@r3067
TTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACNTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATC
+
,2?H'4$>@3,A$+30=G?=!B3'8H2#;,24(E22?'2)5:62.4%%E,8.(H3;2@+F=$:%@4#)>:3@%>1.@>-@6#":68-DD1&9((%4G%F;/!C&;/)CG4<'(&G.6F)%.?8@&'/1B*"$B)@8';.4
@r3068
CGCNGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCNGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACAT
+
747*%H&+<:!0C;G.-6)-BH=%B>1?.DHGG;&:(5A45':FG298-476F2=3$0F?@BF6(;,&8"#)$@87A@#9/=*29:2.G6>0H,%(389:5!AD&D92):.*>7#,EBB,A,;&("4?H+*2@:D>7-<4@B51==*A&-7F$
@r3069
CAATAAAATAATTCCTGAAGATATTAAAGAGCNTCTAAAACTGGTA
+
8+%C'92,#>5G!$'>:5#A;9!<@'/>'-)9A#$F4ED&%:&2#0
@r3070
CCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCAT
+
,<.<,,4;A8+=ACA25*-:@9EAC*;1F4.=><2*7?88<B7E:@B*+FD9$-(52:&
@r3071
ATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCNAGGGTAANGAGGTGCTTTATAACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAA
+
D1AD*2A*=H+2,9/C:F2(552/B;'".+?;A*66-79>C?/CF>A$G"-%2%D7>2$3%#%4=+2>977$(B;#8)2F>CGBHG!C"AG!949'3&*?1;(*(9E<<;*/&+F8*5>1.B5G4GC&68C4!06CFD-
@r3072
CCCGCAAGGGTGNCCGTGATGAAATTCAGACACAGATGCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGGGTGAAACC
+
90=AE:664%:CG"9"$;,3.?514):A?!+?/72#,47<0?@76#>03HD';5G#F=GF6B$<*@3#H911C<F3HF=3&,,(!4@3=8F40#@*
@r3073
NNAGNGNTNATGNACCNNNNCNGNTTNGTCANACNAGNNATTAGNNTNNCGNANCCGGNAANNNGGNTNGNNCATNGTNNNNNANCACCNGNNNNTNANCCNNNNNAGGCGACCNNNTNTTGNNANNNNNTTCNTNNNCNANNNTTNGNTGTNTANNTTNNAACCGACATANCNGGAGCCNGNNTGCNGNNTCNANNTNNTTAACGNNCNNNNGGNCNNNNNAGNTNTNAGNNGNNNCNCNGCN
+
!!$$#"!#$#######"$$"$""###!$""$"###!"#!$#$!!$$$$"""$"#$#!$!$#""!$$!#$##!"$$!"!$"#$""#!#"#""$""""##!#"!"""$""#""!""""#$!#"#"!"$!#""$#$"$""!!#!"$$$"#""###$"!!"$$#!"#$!!$###$!"!$$$!$!!"#!$""$$$#$""#"$"!"##!#$!$!""$!!$#"#"!"#"#$!$"$#$$"##""!"$#$$"#
@r3074
CCAGAAATAANCCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGA
+
ED.9(!-@2/96)&5:3&)2/D>HG1(1>7B:!5;1&'642?)=+&@/47#6%6=F*?8E5B/,)@0'C&5/<$=<.G'<0.23GD':5A+:*7H0>#..66*:D=$7.<:4E,!!E)16(@+?,@A8?@@=3$;<4*7?;
@r3075
CNNAATTCGGTGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGANCAGAACACCNTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATNACTTTCCCCACAA
+
&!$+'$#+$%##*&%#&*"%#"*+(&'!&())$'$($*"*!*'&(+')#!)"$(!&#**#'*"&%(!)%%%%")+$+&')*+")$#*$))'(&+%)('*+*'%(%#+'"%)&)"+
@r3076
NTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGA
+
$?=%9A%F43<58,+F:25(<GC%/>7,B5!H*6.:5(H62)++-$8;=)<C#"%.%>66C,9<9?6.3-:+=G
@r3077
NCGGNGNCNAACCGTCNATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGG
+
%"*$#(&#!**%&&#%&%')*+&($+))%($&&&&&'()$*"!!"!%+!&(#$)"%&')###*'"##&$*&$"()"+)+*+)#('"''!&+%'%"&!"#+$%!&'*&&)*#*($#
@r3078
TCAACGCTAACTTNGAGAATTTTTGCAAGCAATGCGGCGT
+
-72BH0"'+0(="!:C&C;+@/9.C"<7F&.8=";+9A2"
@r3079
GAGTAGTNNGCCCAAATCGATTANCCGACATTGAANATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCAAGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTT
+
(%'')*&"()#*+&%*'$+!"$+&#$$*$##))"*&+"""&'!($$#%'$*""#'!!%*$%%+#"&%'"(($*)(%'&*$&+"**$'"%'"#"#*'#*!)+#))$+#("'*$'(#$(!!$'('#$$"+"%('!(#&("$+*%+$"#!*%!(%%#)*%()'%+#(#&*&!#*'$$$+'!%#'*+)!&&%%'"'*&(
@r3080
NAAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCAGAGCGCGNTATGCTGCGCTT
+
$"+((+#%&+%&#*#*))*!&"$!#&+!#()'%'(*$'*"*#&)'"!*$#"%%'!$#("()')&)!)*'*!%)"$!*!$"%+'
@r3081
GCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTAT
+
40#?2;EA=2H<G/D>F*.4!<$;4##8,-A':7"$F3B6)3
@r3082
TCNTAANAACTCNAACTGNAATTNNNGAGGGNTNTANCTTCTGA
+
&($**)$%)'!$&'%%#$$)$!(!"!*(*))$)"((#+!**"#&
@r3083
NANGTCTCGNTATGCNGATNTNCCCNTAANGAACAGCNTGCTCAGGGTCAAC
+
!$!(**$!#'''*)(!&#&'%!')(!)!("$(+#&'+'!#*$%*&&#%+#*"
@r3084
NTACCGGGTTCTGGCGTCGTTCCCGTACTGTTTTCCCCANGCCAGTGCTTNAGCGTTAACTTCCGGAGCCACACNGGTGCAA
+
#")+'"++"%'%"%)###+%!"%"&&"+)#*$%'&##(("!')&++%*(&$%("#(!)#$!$$#!)&$++&$&&$&$)!*(#
@r3085
NCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGNCTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGG
+
!/@-2H,=15?.$4E7&5&0-26)0<+6)A+)D)'(-G-16#.>0089:(".BE#:,%6G@+$.2>.9&ED4<0DF/><*$+'=??<554G8,'C/0"5.+"A@C/+76(1:<D$50/
@r3086
GCTGCAGNGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGNTGCGCTGGCCTCAAAA
+
+%'+&*!**%(#%)&+")%'"!##%*$!"'(')$!$+#&&%"$%'!'$*("!%)$$*$"+"(+!+!&)"''+()%#"*&*!!)$#("(+'#++#**&!(
@r3087
TGCATATGGTGTTGTGTGTNAGTTCGACTGGAATGATGGAAATGGTCNGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGNTTCAGATGATATNACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCNATAACGCTTCACTCGAGGCGTTTTTCGTTATGTNNAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGA
+
6!.%688!@0*&=#3>/(">C-%9'%??9,=0B=-?.+B/%E,C/4,45&-@1<(-!"F/1B/H;C$1H$/(.:%GHF&)?-$5>(F#8<6,:1@:;+?;%6<:FB3(6#D)DD4?#C8"+!<,#<.+4E"4<(<=>5"4D>+095EG&2@2F-#%<9ED$1HF;GB>G=G?0.4?G+H)&*,"<-8,"?H$(7/&)<.51(4+)+>2+C";'$/3F?4F/)@@<(1D?6*3?58740$DH73)F?#FEA71"@%!,5D=,<=50-"-HE3=+59-#2.>?>GF892#"(H5@>-?C''6C/C$7/=)2!>!B;(E+03A'+*<@7%$%8!8B66)>A$6,A&4=2
@r3088
GAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTNGGGGATTGCTATCCCTCAAAACAGGGGGACA
+
>%A9,,G7&5@EH6)79;7+-B>,-.<D)$30##'"(<2/='D+!7="BG+A@E;,91G$FC?*%%,*%'6?E'**
@r3089
NGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTT
+
#+)'+*(""'%)$)%$#"&(%!))$+*))%*("')+'!'"''+")'+
@r3090
ACNGGTGAGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCA
+
($$+"!'$+)))%*$%)$%($($*"&")'$%#!%&)%"()%!)(%+)'&$&
@r3091
NTACTCCGNGTTTGAGCANTCACTGNTGCGGTTTATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACGGCA
+
%E@?/>H>@9A0@$>;&;GE/AC.A'4HB1/">3)#=);+"4+2<F&:&B6@DE!/+#*A113+$8!1B$-*FGA1/.49)D@148E:(.6',29+-1BHA6?B:,
@r3092
GAGGNCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGG
+
!$*%!+!*"*&!#*'%&)(($'&()'&""$&"'#%+"'!%($&"
@r3093
GNNTTCNTCTNATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATATNGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATANGGAATAATATATGCTTTCCATT
+
&$#&)'$"&%(*#)!$$)'+%"*$%)%"*%"%$')$'!)*#*((#'$"+((+((*)$$#""$$&''*&')%$!()#%)##&(++&$""&*%)%()'&&("')())!###!(('!!(%*(&&+!$(
@r3094
NGNTGTTCCNNTNTATANCNTNTCCTCATTNNGNNCNCTCTNGAATGCCCNNTNNNACGTCNGTTTNNATTCNNNNCNTAATNTTCCNNGTNNGNNCGNGNNNNCANTNTNNGTNNAGNCNNATNNCTNCATN
+
$##"!#!""!!$$$$$#"####$####"#!!"!"!!!#"$!!!$"""#!!#$#!"!$$$#"!#$$!!"!$$$"#!##"$#""""$!$""$$!#!!!$!#"""$!#!#!""#"$!##$"!$!!$#!"#"$!"$!
@r3095
CTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAG
+
/;!7&5<;%-2:)-<DH7<1;+@#:=D$.5,!,!@+);'D>&.HB02=:&9A34<.?D15#(.G4EC8$DC#'0+24-2"G=0
@r3096
ACNTTCGATTTCAATTTCTATTGATGNTTNCCANTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATAT
+
("&#+'!'%)('##++%'#""%*+!"&'%")%'%'+(*($#"&$"&($!(*%#+%+%*'&+&($!*)+"'"'+%!!'*!
@r3097
AAAACAAATGACAAGAGTCTGGTTCAGAAGATAACTCGCGCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCGCATCTTT
+
F6/762GG+E*)("-(7$'&>H'9,2G)</-.>B)2&<D,*G58?7%0G:1</'H%C:=83(H70G.B8C/"!@0<6*+AG99HCE=B"#=8F=*B:-B75)8-'95
@r3098
ATGAGCCAGCGGGGATTGTTCNCCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGNTGATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCANAATAACCATGTGGTGATTAA
+
E<D6>A#0H6.45.6*&%*$CF06!?<A(H;'45$511=C.(4'(2D&A<3&+1*(F"",A4'!D?2<3399!9.9.GE.-G%'8)G")HA&*-#5B;)/-!%B6-8'8/*B&A87?)0/:6;$=+=!(!3(%1BB80$+(BFA(@"=+DG@A<CE9?G.BG)#9H%A2%*<*=E6@,*&81!9/H:?>E+&H14.
@r3099
GCGAGAATCGACAGTGATAATTCCGTTACGTTACATTCAT
+
5-DC,%'+61C)4.?#,F+:#-G(!F%=<$G:@:"1-''D
@r3100
GATCCCATGTGCGTGACGGACATCGGGAAACGCCNAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATG
+
.:C&>(3(<$G2?00/-H(A."A+"B<46>35/=-D;,29>6$EE.16.:1(9HHEG(D6G/C1"D**/86506>.1F%/,99(E(7:('(@3&?%(15
@r3101
GAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAG
+
C,0AE':E@"?7*B2.(!9<6&$E,4B8'=26F/(<H%<)
@r3102
NTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAANGAACATTAT
+
+!&&")!%*$"'')#"&($##)")'"#!*)%#+#%#)#)#&%'%!$#")()!&%"#"$#(###&+&#!&$'&&*#+"*&
@r3103
GTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGC
+
&83+,659!9G@040F<F2,$"/!H7''-(9>FDC5&>"'7E5B$3G6:'D96;F5=ACD%FDF<!>*C!-H3E<F,!-?2$#-)+
@r3104
GATGCNGAGGCAATGCCGATGNCGATAGTGGGTATCATGTNGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAA
+
7!:5%;=H>692*<?>3C!B=5:,G39+E,D?/&@9E98G0+=D:5$6#31@+F5'-E9G)>G9FD$0G.'D,CH6'?E;0@9)%B3@2*<-E%5)@C&><%
@r3105
GGGGNCNNGTTCNCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGNGAGGAAGAAGCCCGTGCCTTTNCCCGCGAGGTTGAAGCGNCATGGAAAGAGTTTGCCGAGGATGACTGCT
+
!'#%$*#!%%)%!+#$(#&"*&(&!)*(%'('!'#)!%((#$+'#('!(%)($#(!#"($$'!+*)*+'#'+%)+!)#$*($)!'#'**+!*$('&!%*%))#$'#!)(&)!')%+%#%&$*!+*
@r3106
CCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTANCTATACC
+
(%4H!+?F4C9)=#=G,-.:6%C44680;8.7@-D(1?!A1%$/!,#H'26H@-
@r3107
NAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGT
+
'G6"8172'A1G</B"!;;"6F(+5A:67>F$6@/1/?9*
@r3108
AAACCTTCCTCACCGATGGTCAGCGTGTCTCCACGCNGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCNCACGTCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAA
+
(*'"!)(#"+(*!*##$"($!+$+#)''$&*#)")#$%%(%!'$%()*+!#&)!+(*$*!%%""#%!"#)$&)##+')'")%)*!#!"&)$$'%%%"!#$&#*!(()"'*'%*(#+!+)+'+"(($+#'&(+%$)(%$
@r3109
ATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTA
+
'H-.?5F:$>;B8-5EC3()$'"13C/#%0??E%*C9E5.ADAB7#0H!,C/!
@r3110
CCCAACTNTGACCCNCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGTGATGAAAAGTACATGGCGAGTTNTGACGAGATCGTGCCGGAGTTCATCGAAAAA
+
!)&(()'"(%$'&*!+!$*"$("'!&!($*#!)*!$'%'')#$$($!#((!')+")*&(*(#$""'!+#('%&+!#++"*!+(%"')&*#**#*+(#)(#%!*)&)(!!&)
@r3111
TAATCCGCATAAGCGAATGTTCCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCA
+
#;64HGH:*6=5*@#B*7CFE"7C59"D/A>8$0G'/'5.)288EB;FF=-<,C:#//.0.@:+6)%-9&!(03"0#A21.24&*CG?D>.2D.EC.3G;.)
@r3112
GCGNGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGANGACCCT
+
8)5D=@#3G2GC1:8G=2,$&.4C:H"'F9"C9H5"26#7,-*54='A"!9%!>:1;)H518%06+B6>-GC*++?G>;B
@r3113
GNGCGCAGCAACATCACGCTGACTCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGG
+
$!C1(,@/8+B>C/H@2G;,,#%G),:?7D%248)F>!$@E0800/7/%G7?:@/@DFH--1%5>!$@@@-5=.!G1D@F68:D5,&$
@r3114
CTNTNNNCNANNNNCNNTGTTANNGNGGCACGANAGTTTNNNGCNCTATNNNNNNNNANGNNCNNGAGNTNGNCGNNNCNNCCNATCNAGTCANTTNNTNCNNNNGNNTGATNNATCCNNNNCTTNTAANAAANNNCTTNNCCGCNNCNAATGGNNANCCNNTATNATNGCGT
+
#"$$"#$!$$"!!#!"#!#$"$#!#!#$"#"#"$$#$"$#!!"##$"!!!$!!$"!"#!$##"#$!#""#!#!""#"$"$"#!"#!$$#"#"!!"!#$#!"!$!"!!"$$$$#$!#$!#""#!$"!$$"!#"#!$$$$$""$#$$!##""$$"#"##"#!$$$"#!#$!!$!#
@r3115
TTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATG
+
@).24(,#:<*$D8G4*3&/4/584'.CC/7''6;<,$:?-6H'=?$$B@?.*507+9
@r3116
TAGAATTAACCGTCACCTCAAAAGGTATAGTTAAAACACTNAATCCGGGAGCACTTTTTCTATTAAATNAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTACTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAAT
+
+0/1H<"A'0.G"$(47HB!2B:')H2%>BA099*,G5;/6@FE%E8774<>-A>4-A97('0'3))H'DCBA8:/3#&36"8;9!569"?+=E1;1&E435?&81'95(G47,61$2C"BD;$$B15)"##,@@,>?"-)-)?)964A>@!!!F7D&/3-4)&EG:!5B3(1&:87@$%(#:9#B2@B/3?/!8#E@/)3*!=E@+B.1EF31%(>=D=)E.;#*
@r3117
GCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCG
+
4&::#2?C9'3+)/-&='AG'(@:#:?;%E;94+"345?$)F#!92>(C5(&<2H>B:4@3;B1%#GE!-=8**7+:16A&1./@+,&!FC@E'5=->*D-++<@@"$F&-@40<E"4,B*1G-7
@r3118
GACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGC
+
;2?8$'=$2<;#+936&B69C,DD@-B"0"GGH5!0F4)G@?(5;:%&B@?F$H/G$*)/&7%!:&58*C@&1,,9F;E10
@r3119
GTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACGAAAGTAGAAAGCGCANTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACC
+
!7EB(*2:*,>'A=)+B6?+HD$%%AB8H7(3'"&'=2-:-+''.=H#AA<EBAHB5G2*$"E28"+"=H>#;H-105/?*(*5/$G#>).(91#F"H(6248$$A?/!D+"?<$*C'*7("H4:+@H(<7F'(H!%D
@r3120
CTGGGCGTAATTCCGGGAAAGCNGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTT
+
.179-)-'7?+$8!.E>4A#8675;H/'+H;D,?4)0(*6(<'$3H@@4!&'%E!G'FC;C$>52D36'HFE8%)'*6H)?1?.(F%D:F9(F('0<H&A2#)(9=:7&H3?=7#3E04B
@r3121
GAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGA
+
CH/8(2:D4B3-*E8H:CF=2==*4!A#4#>6<(,@>#%-7,=D=-D#'#C.)!>*7@!/A./!8A":@E.D&H*=8(27:;=;/3G;#>/:#14EG&=AA#F?.F7'#30,G%BH74H?;->"&1#4/D5E6#94#5?7B727A*F6*:98GGH#$+?'-D<8%)DD76."C(*%;)6",).H.6B!9;?5>$6C;;@3963)/F:AC<4*4=++C1')F=DGB,@33*EE'/77HC9;,)+A979#=8*-!.0(3):)4181?9C)%H04<"&:6C/4B;@+//,'B(14=;(>568@*EACB!.-C'B,#B*5",-'F0":?#@+8
@r3122
GACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCNGTAATGCGTACATGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTNT
+
'+'(!&*)"#)')!##%'!*'+&"%##%'*$&*+%*'$)!#$!%"&%!!%&++()+*#)%*+'#(&'($!*()&%)!%+$#%&+#'*&+$)+&&!#""($!&&$"#%'&%$*+)'!"$(*((!&&*'"+$
@r3123
CCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGG
+
@2:6D9$A=7)B.;.&EA1>B03"$/#*2!90//?A'6D$$2>=H57#:2$!8%(<,516#H3<;+,9%--+:G
@r3124
CGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGG
+
@0"AB1?D(D'.>=+'$-$><#*0B6C(::8,7"G/*&A83
@r3125
CNNNCTACGANTGGCGNNANNTAAACNGGACNTGATCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAATTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGNAATCGACCTGAC
+
"*$#&('(*($)%#$$!$*!!(#()*!%*$(%&(%%+*!'&$$%$$((*#!&'"!#$+(!%#$&(+&$"'#!)!#%!'"!#$+&&(%$#)"$!)'")(!$))*+%)+!'++'$!'+(!*+$''&+)(++((()#'&!!+*""*(%)(##*($("'**)+((''&"'$(*+#$!#(&))!+!%#+(#!+"((&
@r3126
CCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCAT
+
5/%@9192.-!9/49B(18792:9%#2?2'#C/+=744GA4,0*!<%.E<1.D?44##A?%9
@r3127
CACACACAACACCATATGCACATTTAAGTCGCTTGAGATTGCTATAAGCAG
+
;3+0>'"7(C;%*:'C'E=40D)'C+2H5@0#,92/@*&B!%-%#3'%11?
@r3128
GTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTNGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTNTGCAAGTCTGACT
+
>7-)*+<%87%'@**=<5@8?/;2#12A:8B5=&1G%1G!?62#&53.8&F<$@4H5/8#%F!#"B;"#F&%A59+>3C.A;H*38C$AH,$,7@,&"15-C%)9#1C"(A;5DEB.C'+,5;40*.H)B,4/=?BG"?55.G6+:E9:29
@r3129
CCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGNGGAAGGC
+
+$>;(@::7B1CC@.6??*;FG(A:-;D550:8$%?A,>C@H)+$;5.548*9*3"F9*&@3.@)+"A!
@r3130
GAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACC
+
9G)4/.F@!!:2)36:(A7!(%1H&%=B6-H7B3)D&07"89(=-&H:2<<'2"
@r3131
NCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTCATCNCTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCT
+
!.#G.C,09G,,:4A<1,B&)GG2':.2D@"(!%!303'A>B)8?!#1A;!GH&<F9<1,8A,>676#6DC?'8&<5;9-H%#1@&:4#6#D3?@6/<*>3C4".%27?-$;3#2>+09B191,3/,)#H?'#$3&.34&G)/(8715EF'7>8<5.#2:+'(+5D+'<!9>F'F+7$%:&
@r3132
ANGGCGNNNNNGTGTGCANGCNGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGT
+
#%!)'!"!""!%))')%&&%**$(&(++!!'!'*&*!!)#(!$#)""&%*($+(+"+"('$)
@r3133
GACGTCGGGGCTGACGGCGATGGCTCGCCAGTGCNATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCAATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGA
+
2CC$"8*((-=FEB+0*927E''@"1>+."25F/38AD!+3FE0.?596<.CC:13'0HA!BB>@@<CH"1A(,A?4('&7/F>$&4F(53%0:F<4E(G4FEH2.">F839,?6?8<.0$/7B?2("?0')FC)34$4D&
@r3134
NACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGT
+
"-*,E152C;2)%E8?#-!!"7,,!(!/H&092+FF'$A0C:;%GH45-8!7(?G8)!5&0*#2+;?>9D&
@r3135
NGAAAAATGAACTTGGCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGG
+
"2*H6F$"'3'?G.4&%@>A*B8A"0,G.B8-8$FE576"%F@)6E3HH+H&!C*G
@r3136
NCTNCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCCGGTTCGTGCTCATCTTTCCNTCCCGTTCTTCCCTGGTAGCAAAGCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTA
+
!7@4$?0=769#AG!/;"1339<;9#44@0)%A:2303;092(,)E8&5G,(>0@D0G;:?!%4$694HC->0"62>0:E?5AB;@;>D.2%9$H0=$??8;16341;/!#::D3%%3D/213#BC?G!-?>(&$8=/$=15?<;/@&12:9<.!"B,D>)7-+8@*@
@r3137
TCCTTCGCTACCATCCATTGGAGGCCNTCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCACATTTAAGT
+
'6=2#4:E(974!A5,A)*)2:D2:HF/47BC?*;="E6*269<5&+1H8F!2E10(E2#<3./>#6$21A+7F2C22;-#A;18A2'!,!
@r3138
ACGNCAGAAAACCAGAAATCATGGTTANGACGTCATTGTAGGCGGAGAGCTATTTACTGNTTACTCCNATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTNGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGGAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGNCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATC
+
+!%%)#*$%*+'$#&&"'+"')+)&))+$&)!!!!#")&)'+$!!'##'"#(&!&#$&#%!&!*$(%+")%($*#*")%*&"*)+)&!#"&*'!()$&'$''*!!#!'"(&!!(((&(*#)!%"+*)*('("+(!#&++)!+"'!#"'&&#$'("!%!+&+$+&+&%&*%#+(*%+)+(+"#*(!&)!""''&"+(""#*+"$#&"!"$!"'$''!&)%"#'($($!"+""#$'!'))$%)&&!**&)*+&#!'"('&##&*+!'()"&)')*!)!&)!%%!(*"+'"$'*&!'!'+%%'")("'+))#$%*#($!)$'"+$(")#&(!%$))#&%%()%'("+))$%$*(%&""&"$*!+()%)"%()$!&%&*#'$###&(('**'+!$#&+&(%''($)&#)*$%&$'+"%*)$)("%'"*+'*'#($(%#$)))#&*+$"($+#$!$($"&*#&*!*+')'"*))+%+*')%$)"#
@r3139
TCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTAT
+
?!-8!>7B&.,1?+EB!?HB#A@H0=-4-@)/<GF#E#>0%.7<'F.-?436C+8':7;3%E"F1<
@r3140
TAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGNCGGGTATCCTGGCTGGATGCCGCAGAAATGGACA
+
%E2=/H%#4%*3$=(D<7&:'(,%F7+)F!0G+/1(92&00+E.4/F>("3!7@>-/-=!8"@+%1"H81D>'-!F
@r3141
TAATNTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATANGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAA
+
&?9&-2D$#%.>0.'"=*F/=1AF22EB8&<B#D-2D,')0H%B18DBC?.$E).?CF+,.*DE!.:D'::8C82CD96&*&$%)+&,<08"A3&/129DBE?@&)B2D2=+F$6-(4(@$E*/
@r3142
ACAANTATCACAACCCCTACANTTTGATGAGTATAGAAATGGATCCACNCGTTATTCTCGGACGNGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCA
+
#"$"$($&+'"#&'+&""&$"+&!%#+$"%"$+((!%('()+"'''+'%%$$)$%!*'())%)("!#%($"($$($"$%*)%!$!+"+#%&!*'$%&*)$($'%++##()*)&+!()+!*!#)#*"(&$!)("$'$(#+$#%!*)*!%&&"%$#""'!*%$"!#*"$&!$(&+$"&&*$)&!%(&)!*+%$+&&&(&$%(*%'$&#(!**'+'*"!%(&)$(&(*%))#)&(&!('!$'&&#!%(*+"("!)((+!+%(%%+)+
@r3143
TAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCAGAATCAACGGACTGCGATAA
+
<FF1EHD0@+*:(5H;%B;AG1/*?C?E>&6>*(G&*+47:<G1/#(-H$=F+'A$G6-".#8/B"E%%2C3"$'4*0+$.+H437,@96
@r3144
GCATTTCGCGGGCGATANTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGC
+
CE,4//DB:950G"E*8G'01*H0:2:;.!G3/8>#$)<6+!:A%:1H59,;E;3F,,18FF,9F$:+H'&H&7<">*FGD(<G55"%:.4??G-E#C='516?=,D,39;%-D1*>/>(>#F'A=E9"=#'2<5@?BG&@B5?C"C8<?D3FA.61?DD&$A7(:8/.A"<*9(&.B/&$66GH75G$%)?1%!'$0%47DE:G"F;CD+F:GG@+;<(A2=BC'@&2##2B/D!@3(-=:;:'?H=;,A*57124E#(29,6)7
@r3145
GGGGGGATTNGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGNAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCGTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCA
+
*-7;H)077BF#+&%80;>94E3B9(2*9%"B5(+D"B6".(5@"01>*BAF76/#0:8"A<>(<3E("F&2'-:6<++;!HC5(C'28?A21>>'0BH)14%6C4A=10;3/3AB<,C.85=@F<(A&>4B@D6<97G1-@E4HA#?C:B
@r3146
AGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAG
+
=$8A+<$$(?+D4<FDF37H*)-87+H006,9EBD>;:9*F$34#)E49$--@!C&5:67%9#'@7(384,(&D'1@H5,'2#G?@+//#&GH4=40!B<)E91$;5A1-,3">"#>F7?8'A)%;>)FH'86.>*"*=F#+>A*-??'6C=#-79(?:60A'$8D@:D:!
@r3147
AATTGGAATTGATTCAAATAATACTCAAAAATGTATTTCAAGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATTGAGTNATAGAACT
+
9F3$'>29C,A*)>0&/+*58H4/620!,=01+&4=:'F(-)$25=D$;149/=-B9($(?;/H*+)?G)/0115;>0>D-CE6(?/EA5%C7D49=E*84%&6!-@-A#201H-,@6'<9,!H-E?-6F006$5?6$CHF.E4!8*;(!3G=65;'=@.'6A01#/E7&9:1,/*,#7'6/AG*E*0);*+
@r3148
ATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACC
+
E;);9:4?G$++,CG6E(H;*CBC@-A6>*&FB6.5!H-7)%!11>>9%A$/0*HD+6+5F*C5'889,F&0"1
@r3149
GCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGNGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCANTTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGGTGNGATATGTAGATGATAATCATTATCACTTTACGGGTCCNTTCCGGTGAACCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAAT
+
*+!B+D+BAC+-7/7!B*98/C-7<0;#5);)?,#%>;9$!,#?-:/HE($8"0''C"$DB/E%E!,$84EF80("!C#%HF7,71'C,;>?0@F-'7%F9G1F7&3AG4?A3"";8,AH>F30='9BB?*?("7%(&3CE%A'@,G??&-))HG7)3!&H6(>21-$-6:'-$?<?@F&+;>H2"!8=+/(/E!)',9'$!("7%0*1:E2C4!%)9)*E,8;))61(*@-AA0F;*B&G,-6H$><4>A-"BE</%HC*0H2EB2"C0#+G98(1$/16AFCH7(CH4G49@/5C>CH9'A6B95HH%8CB0$CC($G:0#4&&6:5'3GA@4+>C*DH$!3D;D9&3)4%?3DG5?.1!?$CG-!-6>-5"E+G@'5F"
@r3150
NATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCCGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCAC
+
%1G"':F@GF!>-DAC1-,01<01?0*B(?&6A7!<G"),$-7/:7B0<6'5%'B3C,G)@?E(-F&E.#5%*&'-G)391&3C#2;6<E?1,F@E/#0G7'C;A**5;A5<&&&%;))$+>!D<?7=89,;H,,!2FH#?H&/6*"&"&G4E9.7+78(6#:2*-&9?#1:9%.82
@r3151
NATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAA
+
!G$F.=C)A"4%)>9"#+!&9*:"7'?,&32,;@1H6+.=
@r3152
CAGACCTTACNTTCGATAACCAGAAGACCTGCCCNTGCCATTTTAGCCGCGTCGC
+
D4A7'88#G?:DG34:H#E/%0D&3BD/26<:*@6C.B";%4(983=$A".:F=!
@r3153
GCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGTATTCACACCGACTCATTTAAGCCTGGCAATCGG
+
4'"/:<E:&-1.F&>=3F,8#1*B*=%?8!C3%BDA$($?97B696?C%!DH>B"/F?)+(;(-1,'$>*C+7;>(3?9;B/-0(!B)>BB*)G0;H>E+#)**>4H7'+EF8:9E9+>;E0/62*9F?B'24&@"9G)E+GB>%$BE#8232@A>F82@0@(%!
@r3154
CGTTATCTTTTCCAAAACCGATCTCACTCTCCTTTGATGCGAAN
+
@C&;+-0@>%+,@.**7#+2:'7%@762G>&9'E%:"D3!?9##
@r3155
GAANTTGNTNTNAGNAGAGCATGNTGNGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTNTTGAGTCGCTATTCAGAGTCTGACCAGAAATTATTAATCTGNTGANGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTT
+
$$)($&($*'%#'*%%'')$)'%+!&'*!&%#*#%)*#$+$++%)$&#+)###'!)*'!"#%")(()&$+$'$*'('""'!(%'!#(+!+*#%!'+"+'"#+(%&!#%$""'*"*%*"+%+%**'%$)%!*%*+*!&!")"&+!(')%!)$$"+")$%%$$$(!('('#("+&))"$(#)')+'(*##"'##'
@r3156
TACCGCCNCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGNCGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTG
+
7A=B"6#3$=<$'(4BAF@#4;7A7,2!0*4#+68*1,%F=A6&A1D=D:9)%?&4$'B#*?1)3,C%=GDCD&?,B(1>%G+*#C0CBF?5&$!?691=;G?,H&%D';756G4G#C&C@0E0;$'H=4H&DED(
@r3157
AACCACCAGGCTATATNTGCCACTCATTGTTGAGAGTGAGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCA
+
<7G;6574#G<<&%(1.#G=5*E(?B+<E776@$+D&=#53!(&.@7,"G(!-6;=99!F58D47A:/8G@0=91#.4BCFH8&A&H!A"-;&C$?+.;'/D?+
@r3158
GGGATACAGGCCTCGCCGGCAATNCTCGTAAACCATATCAACCAGCT
+
0BH!?&2+:8#0=1:.,07"G@7518!3++2B):2&@=B.H%3:GE>
@r3159
GNANGTTTGCTNGGTTNCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCAGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAA
+
*"*!&#*''*$#&*'))$+'$$!$%%&&)%"#%#(+)#&+!##%"*$*(#%$#$+$!"($&+%#'#"(#(%('#++"$''"&#)*(&#)(%'
@r3160
AGGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTNTTAAACATAACCTTCTTAAAGCT
+
%$+))))("'+&')+*#)%'$!*!*+#!"($%!)*'#++$!+($%!*+!!$(#+%#"&'#$&#*'''
@r3161
GCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGAGCG
+
60/5)6.%?-D41.@.2<;)&4BAB7;#1+>/1B@<()'@8,"F(3?
@r3162
ATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCANTGCCCGTTACGGTCGTAATGTTACGNAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATG
+
B+'"$A;?&8%#@.?>$0D@643&B=/1BC'1DC0.'54!H@&4;&"521%0%%9.(*F!A4(1$E*G71B>>+C+'?#G#@3*>1<.CG+F-$74)(3"F5=-<%,!D36+(+20)<!*@1,)"+3)/@C'5GB'AFG85#&./9?3*<&6?)FB>=C5BH=$5(A,*,'''>%=*5=<>8+'%4':<AF..-:%!12E=9BF>=1!"@3GA0C2G(!%60B*2F&@943$!<)/;(7#2,'$?#1<(G?E:?@C11>'3%A'.+$"8;<8
@r3163
GTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGGGCTGAGACCGGCATNGTCATCATCGCAGATTTCAATAACATCGCCCGGTACANGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTT
+
8-BF%(&C@#<.0-@&)A3+:@D<E9'>C(@((1'9C961:CD/=!@-(=+&99"H*<#('G;-0",@<&,"6456;A>4%=#/??AG(#%9B32-+#B0B,@.$7%5GBHC&8#@:F=*/4.A$90:!,%D-2#-86"90;,@?A<7B=%='1B:$%"G@BF8740(.?@H%C6%4(/-"6=F='51<3=("1,3!GBH:F4
@r3164
NNAAANGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATG
+
!#'")'"*$+"'""(#!(!"()$'&($'####(")$"#*)(+!#$#+"(!&")$$&%+'#"(&+*&((*&#$&&*%%*$(+!+*+$%$%$%*($$!%($%"&+)%))*+$+%$!+#'##!#(!&'#**
@r3165
CGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTAT
+
H,7&-A==F(53'G&<)C+D/1!A'9B@A<6C3%<2E>80(19D/!#G@;5.(7H#A8B5%9G!.B54E*#8
@r3166
TTTTGGTAAAGAGAAANGTTTTTCCATCGATTTTATGAATA
+
?BG%='022;)0?&%;5(".H:">#"134B0131"+@)=C#
@r3167
NTCCTGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCC
+
$')"+#'($"!)!$'+#*'($+&&)(+!*%+$*#%)$&*(&()!&&%''(!%%(#!(('!)%(%%')!""#'*&$
@r3168
AATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCACGGGAAATAT
+
3<3=%1/:%1G=36B7240;GA@99F"0D3A3'C$<.*46FH=")B)'+@!$$!-(H!'=G@074%H'+"-#F3<)8FD;)!A!*C+*<=2</
@r3169
GACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACC
+
C%2#+#96?C40)47'&5"+?1/9@%(D9E57579?4;E$7@'7.ED")2AF@,<!*C#-.62/F"8G?1
@r3170
ACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCA
+
B#F:@3'94#6'0)4;HD(GC"/C7CD:A%D11->;!"A1('&=&A3'**>9@2"/7!.ACBDC,8:$&29#C9>:/22%B.:")B:/%A-("FC31966D"!G03)9/=F)C"H)E:9A4-D-C/.:A85)/$'&
@r3171
AGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCT
+
@B5(9,C@2%-5;&;7$6:22/?,A*#;A0?8#5E/";':.-
@r3172
TCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCNGG
+
+!:<'3E#+?644*E(:8.+;%0:6HB35'EF"5CE$9-,:96*0#"(D;&"/0>+G0$$.G*42
@r3173
CGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTG
+
!9!8,!FBA!,8/+2(<":.E!B>'.G,(B,06BA7:GG%"#E?'=-G7
@r3174
CGCACGGAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCA
+
0>.2)9:048D*&?4%F:D?"7-9<.&>'8+FB+C%=C,H7=AG?0E*''583B/D55&/C3
@r3175
CTGAGGCAGNGAGTGGGANAAAATTGAAATCAAATAATGATTTTATTTTGACT
+
$&>EG22-A0E.CB2B3G*<D2'"D&.28$C-8B"2@5%HD6-B)'D=:4!+7
@r3176
CGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCG
+
),>=1%:=2=CE+95D/7467$=$5@)+6/!(0+5,?D@C:EBF49
@r3177
TCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCA
+
$8H<-?*A%#@EF5/4C1DF,E6E"D/,98>8ED?&#(A!=F%CA4/$4->./GB"%:6:E'A5A)GE,!87/@G!)78>"EF(970!",71>F4#&8:H65=7:2>'&H;$&B6+.3C)718>
@r3178
NCNCNTTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGNGGA
+
!!#+$#)#!#+$%&+$(&+'%#(%*#"&%!$($&'&*)'&$(%'+)&+%)+!!*'"+'+"#%'
@r3179
CTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAAC
+
/@>';$?>C$143+70G%!.AE@$<*<("-,F/7,7%?=A"#
@r3180
CTGGCCACCNCCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGTTC
+
:2@"FC%'4):-'@D4)0;6&9+@!%@D;C)9:4C0,B;8#4#?#@1D2/0>%0E83!8C74E@'7"9;G:!7-:F/1'@(A:%#797*'.<'5$
@r3181
TTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGNCTTCATTAGACTTATAAACCTTCATGGAATATTNGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCAATCTTTTTGCTCAGAC
+
A7@->?6A)#F"/B44$(44&E48>(CH@;:;78B+?0H0+F,(#8#0@%>!)@*<A!!G:G"0G-A0'A+.B"*HD,G).CE82)8;,E/E@(;-:(6+60@7B+46A"822>>5(*(G=0"+:C-+&.);D;&3-FF0//D,ED='>='8=*A2:B4$;2G;B3,=D$',%58B!A<(&!!9BD%%6/?(D=675F#01+%-=89/G"C6-BA>%H=E:79!05A@@E7.1F>F20;H.EE&-!A
@r3182
TGAAAGTANGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCGAATACGCTAAAAG
+
42/"1G,/"7*F;/?#0DC@.6F<9<+"(?7C&(H+EA/--3E!%=3A&=E5.6*'?D5(88HCA.!':7;:-<B3$=?<#//E!=6&=<F$<!C):70-4&8,?)+:<H)"F%?@9G*&F%'21
@r3183
NCCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACNCATGCAATTATTGTGAGCAATACACACGCGCTTCCAG
+
!,A;3+5.,8$;9"?$)@?#9!E4BE,)@*7.&*(EH-D.B#)?6#HG0D.A!0<F.EB!G.>8D%<2F&&*7;2E.EAB3#$?6>)%F0F6!+
@r3184
CAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGACGG
+
.%?+;+'6A6C&9'3<-CF36HB-A@'D@#%&=>=<B!$-#,&&A,(!E-7B6A:)*B8&#DECG6:>B!>:!/@$A)>*')A5F$
@r3185
GTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATNGATNTACAT
+
5A:!:*0@;#?+!D2'7G<40+-/A73C>%,4.(=*"*3'1#'<?.@9H@85?),
@r3186
ACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACA
+
F1,?54B)/'1#DDFBH0G$FA0;6><B!4A4($%F)5<!8%%0,,4)-1*2@,6!F3/-D8*4;?B9>:"-D*0"%5?.3(3
@r3187
NACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATG
+
%)=B'1?+!(*"5?D9555CH"=9>E/9*3.45A9*97C/GGE$=1E)1#(0'?C-B5*2&G"</?4@0.<,4B=C<E%.A5@=E5'"5;'"<9!DHGC.F"#.45':E3",B:GA?1;>3<5D)%),="F)10F4;04F<.=.D"(&<67951&<&4FF>HCDD+F$#,-*''2.>$%2@+E4,5+<5&66%D-HBE!@?7
@r3188
NATCNTAAGNAGNTGNCGAGCNTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTNTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTAAACATGANCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCGCCTGCCG
+
"*()&'#$!""*"&$(++&(&&')##!$%&(")%)(++&#!(*&%+#!(&$"&+)"!&*'$$"$!'!!(!(%$($(*&$!%(*(+"&+*&*")"$%(#"'+""+!%($%)!(+*"")$*!*%++()!)")$$")(%("&%#"'#*&+"#!!$'*$%'"(+(&'+%('%*+!**$&('$*+"(&$%%(%"#!%))($!$$#"#+"&)+"!&!+&%!')&#*!'#%$$&&#)"!''#'"$+'#'($!()&
@r3189
AAGACGATGGGTCGCGAATACGCTAAAAGATTACGAATTATGACACGCCTTAGCTATAATCTA
+
%E4?/88$3&1@'76+DF(#01>(8,BD9->%<0'','GB?.!9#3(G"A**B9?)*%;68/6
@r3190
TATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGNCACTCCGGCCATGGCGTACGCACTGACNTGCTTACTGATNTGTAAAA
+
574!34C'/G5AG&%#H2:&1"*B40>=9$0D,-9"'9!F&,+!'A<GGD*%F?57385<9=:-=?+B'D&G,B;F!+D=;?40G5C+(79C#$E"<$94G45(5%$9-FA
@r3191
ACTGAATCATGGTGAACTCACGCGCCGGATCGCCGNTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCNG
+
>&63D@+4/9&(+2*<D(;00%.<%H8;>A01.C#6:&A5)=?.+-7C6>A!$>'>*D2=5-+2.?3G!%G8?*88(:%:%H8,&7.(9)=#AH!5A=D%,<;.H4!"-DD#0>844)/:;5CD:B'+=8/D/#2/
@r3192
CCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCC
+
21=C?,-"%FF!&FC>*+F1-0!5#5&"';#G<$,4&H,:2%9%0G/0#9($06B3F#;#'>A1D'37>3;.HB+D-G@76EDA%GC?>#5%G?:H0H+C#$?E3*E+'D&/;+EE,%7&
@r3193
TTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTT
+
?F62@@38D6&0#>7H38+.<EF#3=.'';6H86:$(":(-8%?E*0&0=0=;;CE1)/?//5!?.8%,26#@-%;%?(,2),C>B1A/:21)&3.#
@r3194
ANNNGNGTNNAGAGAACGTAAATCTGCTCTTTCGCGGTANCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCG
+
"!'!(($('%('!('#&$*(++""'!*!#)*!)(*"*)$)'("+*!&+)&&+"%&!%("(&(!")%*)$*$(')+#++'#
@r3195
AGCATGGCAGANAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGG
+
%$+$!!+#%%!!$()!!#*&*+$)+$$&'$%#+##(#!("'"#+"*'&#(''!"%$$(+)(*"$%("+((&()'%(*!))#&(
@r3196
TTNACTGTTCTGCAAGGTGTTCTGGTCGNCGCATAGCTGANAACAANTTAGCAAGAATCTTCATCGAATTAGGGGANTTTTCACTCNCCTCAGAACATAANATAGTAAATNGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCNAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTNATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTTTTTACCAAAACAAATGACAAGAGTCNGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTG
+
'#%"*&))&&&+'*&&"!$$!$+%"+#(!'"+')!*''"(%'%$()+(')*)$$!*+)%!"#(%&(!#!&$+#+#'&&&&!'"$$"*((&%$"!&#""&$&$#"#+#+$++%&"!*)*##$)('&$'+*&*((&()$!+*#'##+('''%"!)#!'$"&$'%*&$+&&+*#)+!**'$%*!*)('+%&&###*%!*#%$%$')#!+*(+&&'$$%$#&''#(+%!!+&#%+#'**%*$!+#(&#)$*!*+&&+$'+&!+$"$#%'$&+''&+*(%'&!)&#&'%*&"+!'))#$#!##"%((*++$"'+&+%!%')!)!"*+++$%"(&(((+*(&"!$($()&"!)$("($$%%$%!"!(#+"!'('&')$)$#(+)$'**)(
@r3197
TANGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCC
+
'(!+))$%("#"+$+$"&%#$&')%*%!#'$(&#)+)"+$%#+(%+%!+!"
@r3198
ATGCAGGAACGTGCTGCGGCTGNCTGGTGAANTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGA
+
(=5,$D>0795G'E!8<-9&)$9,H10D0:37C'GG8'1%G9:.-88@F'*+3:/!A9D%*<+1:2G50,$<F<
@r3199
AGGNATCACAAAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGNTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGANGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACG
+
**'#%!)&#'%++&)''!%!+'$"$$"!)%$'+"&#&%(!(!(&($$**%)"+'*)(*"(+*)"#%#(%"!!"'(+''"$('*#'($#"*&($'*&%+"$*')$")**!)***'*)&%"(&#**%!#)")&!"*&&#+**$*"''%"*)$+(%""#+!)'!'(&&%$$+#"*"&')$(!+&$&*"&!#*&')&+))+#*%$'()%'$&$(+(*
@r3200
TTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGGTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTNGTCNAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAAC
+
1A1;B60!7#2,D(18D440<(>0)HE<<>%ABA.&"*0*;FD,"-;1,0=-#>;A;0#&:192#E#1:G()H:;-%)C!F@275)$"5#C75$8-,'74%%2@G($79.-&04,1)782$(1(:%6*+B74F6F#*9HCE@A$2/@E=($8@<8?G$
@r3201
GTCCTGATACNGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCC
+
0E@=A<<*40%2:/"D3(%)EB7>%HB*G4$*82$G@)E7/>0B*=43$"=5C)*650<44/+&G)">==@*A2@@>33#DGE/#
@r3202
GGCATTCAGCCCGGCAGNCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTC
+
??<)3)35:;-&/9B.B#%+#2B2(!%7?@7HB/F=;$;;!DBGF,+/CE922-.-
@r3203
TCAGATTTCCNCTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCA
+
HG,:&4+4E%;=@7C,;>+-)G?=!=75%6<-+(@'G708&0(85&
@r3204
TAAATATCGCCCGCNAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCT
+
"5>4.G0B+"D2/4BB76?@F/F$C3822:!):$3:A/52"(&(+<A,B2?&/.<!6#%/-"052D'G
@r3205
CGGCGCTGNACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATTATTATTACTTTTATA
+
#5;5>%34+<+*6%29>+-:!$690,%BAA<E?HB'+!2-$',4G$0>CB"11G216*>-94C
@r3206
GTCGNAGNCCCGNTGGTCCGGCGTAAGGTTTACGCCCGTTT
+
**$&$"%)%#*&+*!("**&%&($&++##"##!)")"+(&+
@r3207
CATTGCGTANTNGGNTGNCGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACNCGATGACGANAA
+
'(!%*'"&##$(%#)&*$+"$*$)+'#)%%&$+$+)(*"%&&"$$!*&*!!"$"$&)%++"*)("!%'&"%)#(
@r3208
NANCTGGTAGCTNNNNCAAATTTCTNCNGCGGCCNTGTGGCAGTNCAGACTGCATCTTCATCATCGAGATAGCTGTCGTNATAGGACTTAGCGG
+
!%"(((')(!*'!#%'*%!('*&$%))"!$$(*$$#()"+&!%$"%$#"(*"*&()+"&$+$!+(#!$$!")&*$)#!&"(&)'++!"#$)(#%
@r3209
GCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTT
+
3.5C78'H8%/C>G$D'%;G#1E?(?472=C*4'8><'.2->1.?3)9346";%5(/B5;$#6A=./B*@.%%94?
@r3210
NGAGTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTG
+
!"'=>D+A%4B5,H6%<9037B9%A@#*AE,>7H4:=F.0>16"+%,=<:EC6&.;3&4%H>@'
@r3211
GACAAGAGCTTTCGTGCGGTNTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGNCCATCACCGTGAACGGCGTNGCTGCAGGCAAGGTCAACATTCCGGTTGTNTCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCNGGAGAGTCAGCGATGTTC
+
?8?/=1;+:9:,"67,?%=&4+&28BDH%>%:B%,6AEB2+2F(=,+F!#A32BD08!H%$$@&*-DA"H3&648<2>96534:3G$8'954-D:5A#5?HB;6&3#7($=2/+"-6=!#B',2:4;&52/1;,(+=A,<9@.?#-!%@7&';4;$!7#(8$=7E"8835?&-/<,B9-?F!73C:'+H
@r3212
CGTCCGTTATCAGTTCCCTCCGACCACGCCAGCAAATCGAGGAACGCCTTACGTTGA
+
=/D)20?D1.?E,74**:-2414;:-E7C</%FB1+H(!"#1*G3@/2H1G!43+/-
@r3213
TGAGCACATCCCACGCCTTACGCTGTGTGGTTAGGTACGCATTACAGGTGATGCGCGGC
+
-.F""+%!C%$!D@.D(%D0(HE5#B.GEE2?7#4*6?B;%<$/%+01%HC<2>@5/&,
@r3214
NCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAANATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGT
+
$?!B=5?'=9B:?7G#5'<+5!F,5379(*8E"8#$#>6>:0?7)-9A=/&@>.6!!%;#8.1+2H;D@3%!4B;,
@r3215
GGGCTGAATGCCAACCTGAAAACGTACAGCGNGACGCTTTNTGTACCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTC
+
<"(9H)FG;E>178?<5)/*=D06'&>'1/;3C='?(DF5;$5CB5>H00.,$/69$:$@0D&;22'6/"&8/>2"='>E3@.<<%@61B'E7/1C5-%4@@8"GC#.D
@r3216
TCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCCAGTC
+
.43?;0"7G,:AA2-,#>88%2@!&/'*$+9=#E,%+;#=5*!1G<4*7B#,8.E;DC.'%@#:4=!'C$!C)GDG>@;EE=:0(!
@r3217
AGGAGGCGGCGCAACGNCGCCAGCTGTCTGCGCAGGAGAA
+
?64D8G47*AE0"-5)G/A4&!@CA&+"=($#HG31!=;H
@r3218
TNCGAAGGNNTCNACNNGNNNNNCANCGTTCGANGTTANNAAANNTNANNCNTNANTNGNTNNTCNAACNTNTNGNACAGCNNNCNNTNNNCNCGNTGCNTGNTNNTTCCNGTGTNNGTNNANNGCCGNNNAGATATGTANTNNNN
+
"!##$$"!!$$$!$"$!$!#$#!"$"#"!$"#$!!"!#!!#!!$!!#"!!$#$#"!$"$#""!$$"$"!$!!#$!!$#!#$#!"$""!!$!"#$$##!$##$!$$#$$$"!!$$###!$$!""#$$$##!!!"!"#$###!$!"$$
@r3219
CAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTT
+
2<*3+A3$E#F>7@&#@/$>!(2?";(%-6.7&D4':F@.:5@#*687%4:<B)45#*&!/60)F++H!H*"CD"<2:<G>'.D@.#"'90?9,B8H9B*$)7:#34H<B-%1H<?+!7C9#%<H9&>531/"/3AA*B';='3)-B
@r3220
TAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGT
+
-%>D)E!(,8.6E!;'9.%5?&*./D9?,7"3&.B/*8%9"*C%B:9>A&+9-80<A)C@H,'3=+)CA8*"#5.4
@r3221
GGNGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTNGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTG
+
3.+:,8&;(6@A!)F.2-#5BG%"+)(G-2FFD00#C.EG3:5H4E1A?)1DB!2-!FE#.9:AFB:#A6&"*18'".7)#C&(/H.?@0:51;::.80/5!&,64HA;1!:>2A@&(G7ED544!4
@r3222
GNGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGA
+
/;=51!-(&F.0B/D&**FB-90-70-C&5%%)-(1<":H)#(D.HGDG>7B3.)86"<D<C*:AH-9="
@r3223
TGAAGTGACAAATTCTGGCTACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGG
+
!-G.7@=D(67-3%7<@(E0!?@(23E"(</82>8-<?#H#HC(01%:?<83B37>40DE-:AE(*369)7(8&.+8:#=&<HD##>#+!>B.(!)+1>+H39-8"6.
@r3224
CCCAGCCAGGTGACCGGTTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGT
+
)"*)(&+'&("&!'++)#(+$'"+()((%&)#$(!$!(#"#%(%(##%&()+(+*('
@r3225
CTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGATNGCATTTTGCAGAC
+
0@=1%,C5$8FH>&()C/,#29C8:-<6F@D/&6?!*-<B/<+>3/6/8G:/D=43,(6(!D;<$2/G*<691*0E";6FF2+'%6BE">--//!$74C-*)1,3$'7)=1CF7#=44
@r3226
ATAAGGANACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACNATCATTTCCAGCTTTTGTGAAAGG
+
7?$2+/-2EBCDGAH.;3(2B6-(#<6)G4@F7;*0:5H+%>77=&:@:?!9E?@684;@F)A=7BAE"H;7,(3B&G&&4C%'-281;&@C32'<!23,+"3).9"=1:$0C.*4
@r3227
GTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTNCTCTGGAGTGCGACAGGTTTGATNACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGNTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCNAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATT
+
)%*'++"))"%(&*%&&(%("!'"&+&'$)'"!!$+))')*'*&"%$%*#"'*#!)+(!"%(+()%+&!$!#$!*"!)!$"'*&+!%#)*#"!!(('')'!*""$+)##+%$%"##!%%$)*$&)"(&+&!"&*%*!"%))#*&%)%!((*$(!($&*&"'*!+*)%$*'("&**()!$'*#)$(%+()#++"+(+'&(&)(+)"+)$!'&%$"*)#))##&**&('&$$'((+%)*$&!#'%*'!&($&&#)##'&++''#$($!+%"%%*(!$)#%!$)"#&'!)$"*(((!("*#&"!)*%"**)'#(##&(#+!*+'+!%"''"&#!)%$&*'#(%!#)!$$)%#&!((!%%#)))'$#$'
@r3228
TNACGNNGGAGGGNAAAAGATATTTCCCCTGCGNGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAA
+
'#)#*('''*"(&*#$%&*%++(")&!%*'*$&##$$)*$+$)*#"%##(&")&!&!'%"#%*)(!!("*$%)+'+**"
@r3229
ANACACNATCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCA
+
##!&#)(+")!!(!"&##"*&)$$'$&%&#+'!('(%&%+*+%")"&!!'&''!$*#"%#*"*+(*+$**$
@r3230
NGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTT
+
$)(@4"#-(E7<@D?E-(#1E6(+!?4#$3#A/=*=+@!!,?0"!5826
@r3231
NGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCG
+
*#+!+'%+#+")$"##&!%"%*#')#$&&+**$&")*+)!!%&*#*%!%+*"*)+)+$%%(*"&"**+$')()
@r3232
CAGGAAGCGTCCTCCGGCGCAGAAGCGGCANTAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCAC
+
AF-EHA+>:7E-!!!&8@F(8)%<'3**;)!=7-=7.3>!B!#/*G4,%<"2H<#9?G-'D?CC4G@46E&GHB9-.$-!F8E$13<>#,>5HE2D6:
@r3233
NGANTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCNTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAAC
+
($$#,:B*E)9?:;!G#G.?60>&%53!&F5A'3)FF)>=*&7:@6AF=2;"8!)<:03.E9$G;)=()$:0,'!:8(7%07'*!6!6-1.DEE18;":61"B46/<'+63)%"!="E?!8F:'@H*A"6'!=8=A.6H@!/DEF4,F#<$,8F==)#!((>$)')"@"G,(<!0A)6?-+E-C+*==#71A*H>"?1H/$.<CH:(G%0'&8HE68B'18'"C=&E9<!%.8/@
@r3234
GCGCTTNCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGNCGGTTAACTGGTTTTGCGCTTACCCCAATCNACAGGGGATTTGCTGC
+
0419B(+C&04C?E;#84F:=146;<>&AACHE0F>;F;#3F,7CAE%(;=3)52,.C"1:@.E=!,FFH@3GB30.-"(96=7."<:%;-*9:?F@
@r3235
ATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGTAATCGAG
+
,?66!->B=E+263E,!0!"A"92D126(%5+A3%1@:0C6@@6D@-(-+!>BG
@r3236
TTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCG
+
282(CG:3.G.A52F31!%4$?*D%&9C*<:;;@*>C!E*.C+:+@.3#.;7*?C/-#='H6305C-E5AD"3&#F@H-;;H5/%)8;?;#:9''1$';$A
@r3237
NNTGCAAGCGCACAAATGAAAACCCGCGCATAGGCGGGTTCAGGCATCAGCGGCTCANTACA
+
'"')*+%'"!+&#"))"!$)'"'#%%*#'+&(()"#&(('*!$#%#!'&$'$!'(+"$((""
@r3238
GGGAAAGTGTTCGACNGTAAGCTGAGTTTTGCCCTGAAACNGGAGCGTGNGATGGGGCGACCCGACTGGCGTGCCAT
+
+($*$&%"**$%!"'$!#!(%!($*+&)#"")%*%%#"+##"$$"+$##))#&("!+&#''&$!$+)"+&")"$*+&
@r3239
ACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTC
+
+#D--'E;-,D+D:":?%"D(&.A38-0@#D!1);,$8""!2;G
@r3240
NTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCA
+
"78E,?;&B1AHE*=E&;82FF7/%>03B1;0>5=$C;#,>@?D&7A'G+G5ED+3@19=3D8GH0A980?B5;%?0*H@!;.,&F+$A,
@r3241
CCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACA
+
@#A&*D3E(8)(A7+C?5;.9A/DAD=C7E#5&%2/A+!.>GF<,4&127;D6D$6&6.3?'?H!H"C)%"&#934=
@r3242
TTGTAACCCATCGGAAAACTCCTGCTNTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTNATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGA
+
0'(H>$3$1?/D98@4,GE=6FCG:0*!(@=*')5</E+8F&.=C7$$$'(H?(C)?-221H')=36!7H29C)%C1A@(H.+D&<48G/C/-,C'D8$B9:$'((G,!@7%;D*/6
@r3243
AGNNNANNGNTANCNGNGNNATNCGCNANATNNNTCNANNNNNNNCACTGGTCGTNANNNTNANGNNNGATAATNGCNATNNC
+
$$$!!#!!$!#$"$#!!$$!"##"""#$#$$"#!$!#"$##!!!!""!$#!#!!#!!$!"$#$""#!!"$!#$!"$$"$!!$"
@r3244
AGNCACTGGTATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCG
+
'$#'())&))+++&*)""))*&))%$**+'&$$%"%+*$#'&&$&#$&!'#*&&+%+$*!+%"+')!"#"%
@r3245
GGCATAATGCAANAAGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACA
+
05H24&E#28D8AB0=6=E>;$*'6>$E%>,979(:3/+-!?/,,FCDH$!27;E-H"5BD=
@r3246
NNCCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGAT
+
!!>.!&@.?2.H7?G#)BG.61)@#/3F#,&=323G<>-!H3"$/C%B@CD(F>.C#@(2
@r3247
AAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGTATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCNGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCACCAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGNGGATTNCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCNCTTTGTAACGGAGTA
+
6<B,-G@?;52E<?GC11(9B:9@1?#4$,5>9E0H-93$;2.8?=G8>-AA<E#2AH34?"7A;-(+AH;67!64=26D??5B"-1=5=0(33(@!-@H%-4#4*4H+%#?$8711%H@!*5C8A74)2/2+8":%395?-8?B(6$CH)B&H!)2.%*+40@'=&!,D(H%8+98C0&7%/FEHGGDC77A?H&.89$*+F?7(F$&3"1+*;0;H?C.95)/1(7;9*-<9F>;(),%$<!$;FB9HF0@;;"5@&3DD(4)1F@#0//-49%(H53!GHE5?+32<CH&B2:C2+?/#"<C.:4D84$0+:4.>04#F)@!@10B/$.F,B!+"H+4.=4<."'D
@r3248
CATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCGGC
+
0?#F8"#?<$#.-'487EG=23:42D7:>+</?!=88:8(-=087'F?*FBH3%@:400=:G?)>%8)$>4;*14+?$2AE&D,4:)EH&0#7<D9,>F&!BH"8G(
@r3249
ATATTCCTGATGTATCGATATCGNTAATTCTTATTCCTTCGCTANCATCCATT
+
5!59/-F/0-6//B=D!%D.//-BD%5,63110%?D;$=.-<$#)6,+3=7-H
@r3250
CAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTG
+
&44FAG2HC+BE$#-G"+!&1(=8!EG&,@1+HF<,:/G8@41D26$#H$*60;/"#79)514"-8,9)/?@A481A4$*%7AD2/$&?;."$/23!%2!'$@=&E10EGG)7F$F%?(?#C77
@r3251
AAGAAATATGGCAATCCATACGTCGGCGGCNCGTTCTGCACTAACAGATTAAAACTCGTTCCCTTCACNAAANACTGTGATGACCANTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGANGGAAGATATCCTCGCATGGTGGAAGCACCAACCATTCGATTTGCAAATAC
+
EG#-(EC6C205(.E5=3*!D#$039&4A('E-'9.<"8)-*6*/7#5<,.*A*(E%20;%C5!&9<F"B5?*/<4"4(;0GC#5(6HC:;6&:8!)1&AAHBB6<!F;B<>1E7:*@*+0E5&(3=<%E%;B9C.D&0-<8<-D&!/H>(@G'?0@G+$<<7($GB;(!%>!F2G=!<@/'=;G%>(89&;'31/)0:EF@A.%>33:6*'B,3$6E!?.?2C4><)%6>!B#!A4..!$)9<B+7
@r3252
AANACTGAAAGAATGGGNATNAGCACCGATAACAACCGGATGNTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGANTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTNCTGTTCCATACTGACTCCNGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGC
+
#)$+&**+)%+++&'$&)('('(!&#**")+")"*$'%"#+%+*++!'+'*%&(*!+$(&#%"#)+)(#()"'#(!"#%*!#*+%"$''!*#!$"$&)')+'!%)*%#&$#&(+!$%*)#%(#)%%*&&$%&&*&"'#%"$'$(*"$!*&(%($$%$#%&(#+%%%+)%%!+!(!&#+(+"&)'**)(%!%%%#)(**%!)'*+&(*!)!"#(*!%&*)($))"#))!!*&##')+*#+%(!$')))+$#'+!!))$(($$&&$
@r3253
GTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCCTTTACCCTTCATCACTAAAGGC
+
>):8+%4#(=0<6/D2F0+H!,&+.D'=/@H-#@D"(+&F!G355<0)%0&/.A(B;;#>F$*&>:5+3B42H6<E7+=9)%?1)611@A0@-F8C=,@5!*%G5078>GH0(8DE3*%/"99<+7;/C)0B*9A'2@1B@.D3=E198:4C&B),?C@5:,8%@%2<%16@&+2F
@r3254
TTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCAC
+
CEE,5;8A)C1<.2H!$;5-:!G6F5F673;;B>3CG%2!3E*&7/$H,?;4H5694.-#7;/1',.6&+654475B.6C7
@r3255
TTNTGGCTTCAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTNAATTCTCG
+
5.<#00,+(G#$5BC6"<1DA9.&='>!2?<%-(6!3H-#DEFAB+"=>11-*368'CH-#>5AG.,9GCB-'D#"B+.E!1
@r3256
TGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGNCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCNAACCGTTCG
+
B95@(%!A:0"D&G4%83#3!%$:G)#2!$#"/G=$$!B?-8HFF>A,::;@;:A)1:0@$2E8C+9AA6F-DDA;C)#.85F4.<&;9.2!9F%.1*A85D:03?/($#81.,
@r3257
GGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAA
+
#C)2(:F'9#%./?:4=+&-/(-4B7#9?)#58G$,386H:08,?2#F@)/"2
@r3258
GNGGCATAACCATCCGCAGAAGACGCAGATGCCGTNCATGA
+
-=HH*2H*>96C'&FH1*-"70&*8@+!"B4B/CAA!47@>
@r3259
AATTTTTTATCTATTAATGAATAAGTGCTTCCTTCTTCTTTTTGACCTACAAAACCAATTTTGACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTNTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATCGTAACCCTTAATNTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTGTCAAGTACTAATAAGCCGATAGATAGCCACGGA
+
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
@r3260
CGCGGGCATTGNCACGGGTAAAGTTGGGCAACAGGGCTGCATCCA
+
+('%'+#&%*%#'"("")($!%&'*&++((!"%$!'+#$&*)%!&
@r3261
CCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGG
+
3,')!.-%3:&29&,4:D'C=2B)57"C$427/B#>2#:45)D4<(0,:?"29<?4!CA$,HFF6%F&'F=)=&#7*>!*:9D88G27(E#C5#?C6>>%7@:+!1C
@r3262
ACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCACCAGAAACGCGCCGGTTC
+
4)F#$G*?09?F@2@H2!F?C,!B3/*(;+$HF#A'"?B;>#C7%6.&F$5?:9$858-!>F>6=@0D=:FH8B:'$&,FDC
@r3263
NNNGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCNGGACGGCATGACATCG
+
&'("?<$!A+0H9+<+775C'<&"1G,?@.0E6A8B%>":/>C5-E%%7++$290.
@r3264
TGGAAGATGGGAAANATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGNGAACTTGGTA
+
0)G*<-'A4,34#<8?,)3,A:0F$;'(0>F).<'+,=8(<4&CH78GB#!@F+E09.>:=,1A'=)&-
@r3265
ACGTTAATCCCTTTCAGATGACTCACACCGGTANCCCCGCCCGACAAC
+
@B8(!9##)26&;!3=("D(+674.#"(?2)-A%"G7D@!FA?2)&AA
@r3266
CGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCGACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGAT
+
16E88&#;.C3#'2H$47=#.8B.5&(3%..<7;'*?>!-A42B3'>G>>.+:@$'#<(?4C4E+=09<"26$,C49'%-4'FD3@'79*:/("-%69GA
@r3267
GNAGCNCTNACGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGAT
+
#"&("*$&()+%)*$%$*)$'"'&&%$&+!++'#!%!)*+$&)&"
@r3268
TCNGAATACANGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGC
+
&("$+))+!$#'(#+!$()+$(*'!(!!)*+'*")!&#("%+!#''%"%)'%*#*%'!*)+#"%!%&'$#&"*+
@r3269
TGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGC
+
)<,)BHD&'E@7BHE<:)8?9,.")'+D*0!?C.@A3D!9G>>#B%0<0-794/1@@5&!H-<*E'B+:3</%/5D!$4E1)@.+"2#<$1D+*<&64(C#,965@&=;@
@r3270
CCANCNGCCNNAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAA
+
%##!#!(($#"+%*%*&"%!#"%+#+*!))#%%*%+"(*#(&*+&'#
@r3271
GGTGACCGGCTCACCTTTATCGTTCTGCTCATTACACAAAAAATANCGTTCTCCACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCT
+
D8.D*ED,CF=22);$6,GD6:*=H(@)(:&;B,76+E/1/>#9G40E218<A965@C963-.H6F"#AE"!>-3%;-:'-,"F')GG;"A7E%@#7?>=#:($8-*A6.87#G:-7F<06+0;5!:H9E6"2&#&A9!D07@.8'
@r3272
AACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCG
+
4+9$'C(E=4)181?:3"G$":(E+H/<.%:/".B+.)10)2(/7A$,H*057?6/4$,+)%-"B%>>!;;*78,";4?"?A2@82DA8.<)(?&2(*&3
@r3273
CTCACACTGGAGGGCANAGAAGATTTCCNATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAA
+
&?,&&!GHAEDH(393122B6,:2+71/8EG-@*6*@#?-$;04;!(*AA!=6#!E."HC=%H7!-B667G+4!-G?&%H&6%$%:?*E,')*FE(/$9C-!B0$0F4=?<H%<'=(.8C-9,#.#G+6#+2:>@@5'@$
@r3274
GGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATG
+
>//3)E9A4@2;CG99*D:=,-):9?9?=.,3#>45=A0?%B40#)'6)$CF?"6.*1F2H/.3,;1=9>+?H>06*(>&,4#88$#2))4
@r3275
CAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCC
+
B93$%,C45=<)302@!-<0A-2ED12EGD*%$D''-5'&5D(D-=.:"F32<'G>/?C;0G,
@r3276
TCGGTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTNCTGACCGCTNTACACTGCAGCTTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCT
+
*/4*,8-*1+G#1A'.9+>C<69-EC<6:F+;091D,A":=6'F9D6$G:71'FE8.)='8H=F94+AA>G$@%?1F5#15=?5"H@DH&G)G$;G645=;9+@4%H9>FB8<C+0"!
@r3277
TCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAANAAATCCGGTAAAANAAGCCGCACAGGC
+
#0@F!#A?+:H=(7$=H28B/<"@<7>.HG26C.HCCD9?G;FE'>$!(!!E/60(>D--42)H%(+2,'67G
@r3278
AANCTNNCATCNCCCNTCNGCAATGTGCAAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATNAAACCCAATATTAC
+
!*!"%!$!'&'!')#"(&%$*+##+%+)+)*)&)!"%*%')#*)$)&)"$*)"%(+'*#!"$'!"%)##&*)('$")*!#(*#"(%#(*!'&$'+'%'(!'$!(#)+"!($&&+))''#!!""#'!$((
@r3279
CAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTTAAGA
+
.G%B:**;;3<#BD%.G,&$=8A"GB?@$H3!*,B9&?2.*<B58-.D*?GC3@$*H*4:"-#E:F(>(=8$";C%.(
@r3280
TCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGNAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAG
+
HDF&4-F6")G:(.65H9F?!G0<'92BG'+28&?'51$%(".&7<?(560EB69D/G@+#1?9+CADEH2?00&E/5@+A/(D<F+?-3>588A.)5D'FF-#>%%G!?&D@(A8&B"D&%?5(389"@D+8HHFG$$&5")2.>DA:F'<HECC'8&;1
@r3281
TAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGC
+
"H+C06&)*C.9*G1C>;&-1E2&!=/>+4<(&8*1&G'=0#A/H(07FD,C!+H96$CC1&/8!#;@(C;;/4.>A=&(4F'
@r3282
TGGTGGAAACCTCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTTCAGCGGCGTTTTCCGGAACTGGAAAACCGA
+
5=;G(1)C,6!(<.0>%F%+(3+;-<'H@;#.!$+>E<;:C3$4'1<D*)/!E8?#?2-+0#HH"H'>>-2,(B&G-$3E?2FC>6*G.D-!-:AA%@..6$"DH:G5#D)(F-E)
@r3283
CTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACT
+
"-FG)56@91<A:.'2DG@>9%0"C<9;%8B3(G=15!+$090,0&>?26FB<C54C>$02<+G$-EA=!%A:,<
@r3284
CGTGCTGATACCGGCATAGTCATCATCGCAGAATTCAATAACA
+
&+G*G=67@E!46E74(4DE,8&,7;0>"GB$=?97(3)"8&-
@r3285
TAGCCGCTTCGGTTCATCAGCTCTGATGCCAATNCACGTGGTGTACTTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTAGGTTCCCATACCGTATA
+
5$'AC-;/C8<(*,+@246"6:4HA*C::-,+B0F3"D7GA6*74;?(<:#+CC?-$D)1,2"1%A04(.&:HA1;/-@/B6?",,)>A8348(DB7<4C)$;%9'"-1BE""C"D,,00.:H$DHD(+#<6<G>D@44FH&E#/>.75@B-E!26B#;4D?#"9*H>'#(7,',*0/.37C5>6)"BD>8*?@-&"%E4&(,$<$A=BD!@E198
@r3286
CANTCAAATNTTTGATAGGTTTNANATTAGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTNGAACTATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTA
+
*&!)#*$$)"'!%+&(%(*!%+'++$'"("($!$&%##+)(#!)&$%(("%*+&&#"%&"&!$+!"(+$'+#'&)*&)!)""&!%$)#"&++!$!*#$"%%(+(('**!'$*%)"#
@r3287
AAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATGGCAATNTCAAGCGACTTAAATTTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGANGGATGGCCTCCAATGGATGG
+
:C$-E2''&GA5-09=?BG2$;',&:4%A=!*'AF"'AB3>GE4EDD85A/B;#>@"3D9)6#.#GE/+!H$%E$.*?%GB4E?7);6")9@&/2:1"6/:@A:$#(*<"<?!$?'B8-2E96<!/9!1GG7+EC315+%H22E"3C-E/@1"&E<H21;/>G.6(='!@5686$2*09=8.G@&G#B.GH2>)<,E;*F1)8/9*;
@r3288
GAGNCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGC
+
!%&+$(*')"%#'&!""!#&%&(++)#$'+%%(('"++&""$'#$#!+&"*%*
@r3289
AAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGGTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATTCCCAGCGGAACAGCACAGACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCAC
+
B+)9"@,(!4<"3)?4$1/6,6.,@&BC,2:8<*B#0#:E!;0;79*84<A62E!,#90&@(2>C<>;;-//A;C:C;6;AB%D).>.-@=73>85<1'><)(?-A9;%,/#B0C&:#G=;&1*7H:C5">$>'08?&HF6)(4-:8+?6,:A'H:9+#;(3021=-H.,E67+1EF9<7.='$&3$;H956;8#--:86E.;FA':;+/-(+5GH#&&&C=239F.
@r3290
AATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGT
+
9/.5!&@#2*,G>35;D+8=5)HFDA4>%?5.+68('00)*>*=0673D3;,.HDG"17"+5F@$7;16!3-0",>&"&:
@r3291
TGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTNTAGTGAGTTGTATCTATTTATTTTTCAATAAATNCAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGC
+
FH9*&E=E'8+8"1.13<B:4)*D/2*>$#9*@&6?+=?+A!$!,%%/"&7"#A"8?!H9$2%,AD50#B?.?D407G$"5D7)-#%;3.9&?D89GGE=&E'4FF/&630+@%3*.!=%+D+B04H(2?:5'0=!*8,>H-!*
@r3292
CGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGAT
+
;1!180'H:9?,A-6EEC(:&%2?86)9;<6?!.C72>@HH8/"(CB+BH0=168/$H"2>8E21/G?6A0<0EF&?:CDC15<<!-)H15E486#<8<9#(+78?:(-+?B3G-@::$1+!*!H2#D>@"$!$?CG.
@r3293
AAAAAGCNTGATGCAGGTANCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGANCTGGAAATTGCAACGAAGGA
+
A)7G7F'2=,(G8&6G'<-G1.@2DDF"F2.G)""9;%BG4?6&8<566/?<B-C=/+$,A2)$+'0>/$;E8G*#D=
@r3294
CGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCNCCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGNCGGGCAATCAGGTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCANTTGTACGGACACGAACT
+
3C':<")7-F1.GEB4B(F'?E3"A:$D8&7"/?B919:2@-"71-F77,%(;#5,#?>'6"F?3/.)<04)F11D(.8+DC.B)5A=E.F#A!,@2@&F6FA7.:!$<#/-,@?%=EA!-2@)5"'0C!410;<15%.3C07C95087E>(75-E=H-7(36&*/:6B!C>*CF6C--!@=+<=!E==+HGGH1%/&+DA)>C$"E"4*9C<:=9G2#/=EE*>;23+463('F+(A);<C-47=!>;D<623H@1G6'H6%=<"2B$/G,($@,1C!(;%5/.&@((G.A>4-:+#<5<)/-$:1.C6>+F(1#<:8AB<=,A.)3**%<3@C*-:4*"@ECD3;-"A8-A7$?G9-C>)H"G";D@E6(;:5F=+"7>0-"5"!-F30@)0),D=F55&C6$*07.EH4G=&41+8!4BB!&.7/89.53$-16"&(D,5D
@r3295
NCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCG
+
"48CE$::A%)1<"D!.*C=90;"+'5"2+A4G'2!3C&G&@E1"7C"13=)GB:@+GE#:1":$;"6)-<=8;4+
@r3296
TACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAAC
+
<E-&&3E,81459!"62=H&@03D$-#4@//<@G9=C":;.BB63":;-!!(A(.@0#5<?C?F2?).,?<*;1.$<$.:&:>%)+-E3H>5":&@?)3)-!2*.4*$$F'=#*1F967;A:2)1+2
@r3297
CCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCNGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCNTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCNCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGATCAATTTCTGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACG
+
65/<G%"D77/C7,*(4=F&(3@E7;(3F<:?B%17E<E!!B>%H&1;()A@GB82B7*-;*F?6>(/?H1(8@;<#=C)5D>5;/'78/E;>+-7FA?C,&11A/!A4D))#>4B96"=:<G3)504?->=/(%@*&&?G0'/?$C2.(;3.'<=/<'1<.)$)4/9G8=?@-/3.2-3.<B*7C%A$;52980"-0;?7+!H>#8GD9G.53C.B4=,;(=BG%@9H!3116.&-,F5:-E(AD7;@>5/--?":G'E:'#$5)?&(1$3:C$
@r3298
GTTTTGCTGATGTGCTGGAGATCGAATNTCAAAGGTTAGTTTTTTCATGACTTCCCT
+
4)B3%'21D+/;$'!?%1;"0#&2&%>1>6&/??0,;+A6-(@+'/:1!#:55@F<;
@r3299
ATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCTTG
+
B>(.?"G<7"89$C1F4B.<(:G(%BDE9B8)3&H'+4=C'ACG%:A+69@C/2ADBA8$87$3!0F0.H+//93E=6!2)$%20=$)B-B=H>!.C<C;0F9$G6*::,A;H7<B8F1<*0"2C'>.G",%EC!C)#=+*A<6G%2(68%@?*<F0#F=!5.57B5+%=3->$?8+<AE>D%*</:==>?(
@r3300
CCGNCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTNCT
+
("&!*))+()*'*+#+*%(%+''&'%&'&('+"$")&$+'+%*#)#
@r3301
TTTCCATTCCNTCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTAT
+
H'-A.9;B-$#4""$%"!F$HF@*2002@B+G/61$+D.0/=<=C/:F@1CG,"C1/.!:!(:
@r3302
CCTTCGTCCNTCTTTCTGTACTGTTGCCACCCGTTTCCCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGC
+
*D=/.873!/A=".&G)"0/7-68";8;-D2+A.E9&-H&()?(3(GA):-D4FADD%D38+!!?%5C@:5#
@r3303
TACTCNANNNANCCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAANGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCA
+
($%)!"*"")"+%')*+$!%&(#"(%*)$#$+%#&+&#)('')%$!+!&#**)'*"&%(+%&$!%#&+&#+)(&&+'$%$++$+'%!+'($'%!)
@r3304
TATAGNTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACA
+
6B+D7$4C;4:EH"7':BA+G).1'-D.F/EE8AF:=?E5E*=;!>C$BG2"C&&8C9'=#0%#!*B9,A((!@?:06$EE<A/,
@r3305
NCGTCCTCACATTTCNTAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCANCNTCGTCGCGCCAGTAGTCATAGCCGCTGG
+
+#"+!($')'('$))%*)(!&""$$(*'%*&'"#$$&#')(!&(#+'*#!*"'%$'(*"++(()))"$+"$"'(%'"!''$(#")$*(+***
@r3306
CGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCNGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGNAAAATTCGGTTTTCTGGCTGA
+
++5;:C?<);:-0F;//7>C73;+!>-!7=<A'9DA=/HF>>&*7.C<F2'9&(D>9DH043,%1/<8+?4$E92&F2$&)3>'$>E9#;.%#'A6G*6,-?$3-=@#/)CD0<#>?@8.774@.C/#/9FCH*+"!&CEHD;'&#4A<H9,1!H$/
@r3307
AACNGCTNNCNANTCTTCGCCAGACGGCATTTAAANGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGC
+
("%$(!%"!&"'%*++""++*(+#))*+&(#("##$#*'#!($%%$&'*!'!$&*)'"(%+**"''*$#%%+*$')#")
@r3308
CCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACNGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCNGAACACGCAGCTGCAGAGCGCCAT
+
)+)#"$&%++!#(%$!)$!+(%&)'+)#'&!*)'"$%$+'('&(!)'%*%"*+*+!!("$"&+"#%+(&&)*$*!")'**$&"+(&(&"$#&%'$)())**+&$*&(**$#((!#*)(*'+%&'")!$!&(**&'$'+'")!'%#&("#&+
@r3309
GAATGCCGATTTGCCAACGGTGTTCACACTGCGGANATAAAAGTAATAATAA
+
6,:=G".)*2ED<HH7A"E-":,H&G.61:#*+8.<;1$'E0#G%H<$D?=1
@r3310
TTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACNTTACTGATGCCC
+
5*!%@-+1G>>@"/D=*=$';"H9C7<8B:6?1H'0#>E5%;(@/"=+&C$3'1&DE10)E.:C
@r3311
ACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTANGGGGAAATGCGCGTGGGGTCACGCGTGGTTCCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTANAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGC
+
(D0>"'!@!==452%)'5?>8,B"%>89(1F<B:%"52<%&5=('<73!/13#=*"'FD>3H!.C%(CC)!(A1!9=C254@$@4B=E)588>""(#71&D<'!;$27&D4E3.)9%%E23$-=EG64"3E766420EB-"!"-1(1!E?E7A=.?9C7"F!9*>$!76""?07/=0F%7@B$8>F,;)!,60H%0GE!(8%%/&=.3"!:/:*D;:H*&$=)>&*-!$>A%
@r3312
ATCTTTAGCTGTCTTGGTTTNCCCAAAGCGCATTNCATAATCTTTCA
+
F(6E0-#%1)0>%<G@94F04'"E)>(=6--5E=0?'830@B3;H=A
@r3313
TNCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGG
+
+(9(2%&.&H%7'1-2A7$5/@).-!&G"+34;(/3;64'=DG
@r3314
GGACAGTCCGGCACNGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTAC
+
E-,('=!",E":A.A$(F/.)-=0$2@B2?(?*,#D*A+-*:-B.%E,&(GA,=/400!4*,'1+"'1>A33<G>28-7FDA@B?%3'*
@r3315
TTTTTNCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCNTTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCANACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACT
+
,B4=1<'6&&+F-4),3%'/@2/;"E'A6E'90&F6A%/4)==G!)E%%@-D%+.%,C#,.&736,4/#?8$.=A#8<>(BE-($94F2&86:GDG=?G$GG1>AA(8GC</%?#ECE'6=G-4*$!<4247)09*9E1E?;(A14*FD41H3=C-75%'#*H=8!-9E'1#?713,$'=#CA0<#H;+("@EGB4-H')H0B9)'DA2"B#:4:!F2E&=G)B?:,/<0%HEDE%.??'"9-5;/AB/9(C!<0B&G$BGD(.=:D:($,)(3/D6%$?485$>?FB',A*8(@
@r3316
TGAGCGGCTGGTAAGCACGGCCCGGACGACGGAAACCACATACCGCTTC
+
FG;*.-2!!9&5*,5#6*%%A0.CB%;/;$HB0>,@.#3!('4)FD$0A
@r3317
CGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCAATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCAANTTTTAATA
+
.&A'6*F<G0?>B0"G6/8$B-B#9=;:CD*C9B)G:D(9!<7!#D):?$:#,$;7D/G#H'116(*:C.D@.C;%21E1)E0%A&?+<%/42,/)4G$>!A"$+(8?D'*#,2+;9=<A'C
@r3318
ACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAANACAGGGTACTCATACTCACTTCTAAGT
+
@0?%70@5EC@;B5"3487A)/;#9><%3"3C>;1/0F*BF?7<"1,/)+:6F4*D(/#&49=A=/C-57-?1-)(/%;)2:/5617.2F.';5=E,6G'D*
@r3319
NTGGGCCGGCGACCTGAGCAGCTGATGCACTGNCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGTGAAAATCATTCAGCG
+
"+$")'+"+%!%+''#)'*!%%(#$)'&!"&$$&&)#'"*$'#'($!$#(*+%+%)++)#)*+&")*)$)+$*$+&"*'+&&(!*&)++#&'*+$(!(+#(&!$#%&)"""+!%((#(($$)'()&'*!'#"'!"("'+)*%%$&+*"*%(#%&!#(&'&++('*#"'$&$+!+"!%%"+
@r3320
GAAAAATGCCATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGA
+
/##HD<&%=%GH=,@6!/2%09+D214@<*@FB)*E)?;@;0;C:47:7C
@r3321
GCTGGTTTGTCAAACGCCTGCCCCTGCCTCAGGACGTAGCCAGACNGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGNACATCT
+
D?<AE7;'/;H'=A3!2'(9C+'@6(.+7$'#=?B>:%-EC2B2(1=0CC3D8?=9!F@75A3'*6G,F!*+./&?)''$ED4A@)!G1!,E>#+H->'+<0D;AD2<'G6BB)151*#%DD,*H.00G
@r3322
GTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCANGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAANG
+
(+%""&&*()+(*(')$))#)+&#&""++'#!)%'$")&$"$&*))$'(!%&&!*'$$&$%'&'%!"&&!"!!"'*$+%%&%"&+(%!'"$$)%""%+%"+!
@r3323
AGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTC
+
$4?);H9"C&;39"*(A8'=1F*!>>(<?H/*:)5*&49*E7E'B#9(?63$)0?F3+(D
@r3324
TGNGTGCTGACGTCCCGCCCGGCGATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCTGGGAGCTGTGTGGCCAGT
+
##!4=)=6A.?9"659?%E0F<EC?4F0*H+66CC>%E<,?2C2:9"30#;5?>F$4H?$%3'CAE)B1=&1,#<=9?>D2%4==0C
@r3325
CCTTTCAGCGGGCCATCATGAATGCGNTGGGCAGNGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAG
+
E>*<BA8-/(.,EDB-""*-E?*%.:F5/B&4'G&%A@?H)=:F3,039",4%=H$EF8.6-%*/H>&.&@'>@H$HH&C'>D53?(!$&D%+H*(<73E%0!%?27<<#!"3$E:B3(>
@r3326
CGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTA
+
/B.8.5G$!;#7@>45:E.E;<2"=417,"1>5+5478D5="5!2-<7%),7",/C;1F?72/))A(:C4C<<:3('((2,0E;3EB*35,!>?=87-,2;?H!;#
@r3327
ATACGAANATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGN
+
GF<-?%29@'C&*1GD>E%AG-(7EB$8()@E<=-+7EA8*7;,;'(E$%)9'=!*#:6:A8'-(<CF003=$A4@61=-A+
@r3328
TCTAATTTTAATANATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAA
+
/0;"!C2;$FG36B=>+-A7F8:)=%64!:DE-(:'/*AAE4>2(;1@,C'0>#H4/#=.E)!@0('A!=/6C,48#87-=))%:38!H1)4@?*<-(,7$::+
@r3329
AACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTNATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATTATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCNGGTGAGTATC
+
,-8+'3>AF=->48(2*)>G!;=B&#>850")&H8+#+>9A%-/47%#+*%?7>2486"HFBB,/GDF.2':+BH@$E)--#AG$CH1>*;"2"?,-0,A(,9=4"--G7(";1FF173<*6,:<(#+23G3:-'-D.;$BEADBD6H**F@=9%0)=D@4**E(1;C1C%)*3:<7A(3D,A$>H<?5?9D'F-'%H+"1HD618#8.<
@r3330
GGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATA
+
%:%8<=B.+<7?.&#,;',&D)A11<=.D,+>!?-%=BF$=0G+98:>'.5+<;
@r3331
ATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCT
+
=32"'+2C+;:$)&.D6'/,=E5:+80C)11A1;(;C8E(3;@;E=;?B58$!+=8>:5!)7@/$(BB$FF'<!&8A7B:')6:<?64H-B
@r3332
TTCTTCTTGNTTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTT
+
*$%!#&+)$*'+*$)$!%!'#&((!+)%*+%*!'!#"&+#*'%#%)"$%$&&!%)%((!#'(%#*
@r3333
TTGCAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAG
+
!&)%+"%('$('$''%)*!"*%$!#('$**'!'$$))%##)%##""(&
@r3334
GGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGAATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCTTACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATAAAGAGCAAGCGCATGGAGCG
+
71?.(#1A2B#.(%73-:<5=%C%AB:!C4H9%"G2)2FHD&9BD72(6$5HE'"8A+"+;B3EF:(EB,3?(8+!BH28F4->3%GC,8&(*<"<24.)<-HF"-!4.-8)G.;DB>F6:<H89#G21<C*8@,F-$7(969?:/8=82@)<2+>"%4H">*(03.5<A
@r3335
TTACCGCAGCAAAAATAAAGGGAAAGANAAGCGCTCAATAAACCTGTCTG
+
1#0=1!&GG"H5((30+/G$0"2!"/A-8.9@4G.<E19H>1G982#7'-
@r3336
NGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGG
+
#*.26B10#:*)076#>'+/1*?,06<>/=704&;.G,!(9,*2!$**+6*?,%5?(D+>9$:+CHEH#8C6#@%AEH5/</(A/6B
@r3337
TTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAANGCCNCNCTTTCAGCACCTGTCGTTTNCTTTCTTTTCAGAGGGTATGTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAACGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGNACGCGAACAACAGGCACGCGTGCTGGCAGAAACCCCCGG
+
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
@r3338
CTTTANCNNGTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTG
+
)#)$$#&)!"'++(!'*+*&)'''"'&($%&"'&"*+)$!&)')(%+)+%#+"$('+!%)('
@r3339
CACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGA
+
"1!>1675";D@;C1961(<F%;4*8+0":CCB;7/>?@0?2@<%60"<3%E:1@@H==CAB$/&;!4)%=%B"+7/4*.
@r3340
AAGCGTATTAACCAACAGTTCNGGGATGAATGAAAGATGGCAGACATCATTGATTCAGCTTCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTG
+
':&G?79=;HF$#H>D&!5&2'&..EB1;9-=4&C<)<"C911=5=#4H!4>11-B86'F,!:E&1,5<:C61"C36.0(<6>&-+,"60!7E";*'=-.<:4*AF3;@BF40+9&-%1$=9$8<F9(&)!?5!,!C3<2#!#9@
@r3341
CNTGTATTTTGCATCGATCGCAGCAACATCANGCTGACGGATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTT
+
*"+%(('+"#$+$"!'$)(((&#$*!$+#$'#!!%$$%%$((++'*)""&*%!&"'"&'%%#))'*&'$'('&''
@r3342
TAAAATGGCACGGGCAGGTCTTCTGGTTATCGAAGCTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCG
+
A""C*).F/5.F5*%$#*E2A(</77:!69!)4+H6@H;0GFDC';+?1F%:-<.0A??5!02(=-3,GA'2#+<*5"G0.HB0:48%?&C.F"(<D730@*-@(@""%:51B436F?';#2+&"C
@r3343
GGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCGAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTCTTCTGCG
+
/->=:HG4+(-=(#)8<B@)508?&=3;>G,G#+54:91)$9*'7BDBD2<#)F<9D3.@&7FFD4(29!E/%'B6H?'8>2%=9>4*0$:&75C>).*:08(#EE.A)642(-%=*:&;5+H1A;#04&A7@;>*52H')85E475
@r3344
GTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGC
+
0C@'-F1,=4DGF.B?7#%A#<;8)";=F5*G(F&<EG3=-,AH!C0=+<+2#CH$<6
@r3345
CCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCCATATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACNCGTGATAATAATTTTGCACGGTATCA
+
6!9$326EA%"'%FB)68E$,%:%6F&"<508"HCGGF<D8.:@B"'DDA9!B0F7/)B8$D00.H!;@HF*>.*5$D15!-;?>2/<-B.BD=*!@5+0)6CB>09#2-4;<&=4337(&&H8&3&29574,23,'-*D;6&D
@r3346
CGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAG
+
':6'B$D7%1%;?;D(&6-<6$,,;&32G864C//6#2=7#,"D0C=6C!'1%H
@r3347
CTGTGTTGCCGCCAAATAAATTGCGGTTATNTTAATAAAATTAA
+
B"55E-51,&%7)6-/G1"9F'B:7#=.'7)D94>3("<?8,28
@r3348
CCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGTTTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGC
+
9*-/!(-E7@"2@=)?=2E>%/");)1H)G&DF0/-9D)5:+<!C+(%!A-%;1?;.@!!+F;61#AE<@1??2<AH?8B?'4))C"70D?3G7*82'$B#2->+A1#:926HG.=*./6D#<%C/5D1+G7ED'#''*)C<(6/.-A2#:D#49;'/'1F345*.::C+<C=,:
@r3349
ATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCG
+
=2CG@A9-,B?!/F/#,3G80H1$2&HB<.!,->+*.-84A<5%%+#G#E>-B88?&AD08@E*!(A
@r3350
GCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGTACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGTCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCT
+
<3.4,*'D<24'F7=11;9&:B/5.6"=3@,=-9&E)G,G8'7'+25A%/CCC<,0=88G3?,*GF&,3%!5(**60C<5@"<+7%/,1#C225AF0@:#+7'03FE#>@,G=&G'=!8;097393G3:"D0/47E/"9%C&@&$;>5:8H(93A68,$<(#9A/')>6>+>1<9C$?:$D5!8;$7#/-$.+HAC@40>>),-:"#$FF=1,+:F0<;;#/234H089.7;./.?G3D2!>4A81EG#,
@r3351
CAAANGCGNTGTNATCCNTACNCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTAC
+
$%%#"$$&'(%()(&&'!(&($&+$!#+"!#$'*!)!"'%%&!#$%("$'&!+)!$!'"("!%%!
@r3352
CCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTNCATTNATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTNTG
+
1.:4H,@,4'0",<F*9+&5+@+8?6)?67(@#<E>@.7,$3$G'@<2&1734161''4!56'#C6?H>+G@FCD>/"!5""=96&;3B9!
@r3353
CAGTGCGCAAAACGCGGTGACGACTATCAGGAAATATTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCNGTGCAGCCGGTCT
+
++-F+4@HG.F:37<"C,E3&>D4@1DA5-:GB,/D%A0&A5+*4%8;A238F,/GB<+8?B%*G5+(D)##+)<F*)G57&"
@r3354
TTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTANGAATAAGGTCGATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAG
+
#'1'=*,27D307,(9#F2"1/<(D?51*>>+1!:;)@;)A,.'D!'*7<0?A:HH6='-H8=H'"(-1;?H(058GG-D#5.4=/"H)*27G>8FE<@+-7#&#41-*?,0H/!*##G(*F(=+?#&950/DB*$<F&%H4.=14AB9+6:71>>6/2,-G<)D!:$=(;'$!5$E=G983,?,'9
@r3355
AAGCGCAATGATGAGCCACTCACCACGGGCCACGGCTTCTGACTCTCTTTCCGGTACTGATGTGATGGCTGCTATGGGGATGGCGCAANCACAAGCCGGANTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGG
+
%('&!'"#%+#(&(##'*'$$"$#'")*!'$)'"*("#$'#"&%'##!($(&"##%$"%+*#"%&+*&%*)!#!##%"'"!+'''&)%##&*!!"$($!#&+)#&&&!++&*(*&%('%+($"'!+$*!&#*#&!+)+""#&'(+'"+#"'$)&+$&%
@r3356
AAGNCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGC
+
+*&)2B9<->?CBG>CG,(9$30)E+<=G+A21,<--/:6@
@r3357
ACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAAC
+
1)00@+:4./865>,%4'+59,@!%0BE*$E9B0@-#A5AF=<9@7(,&'6,((:,G
@r3358
AGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGNGGAGTCCATGACGAAAGATGAACTGAT
+
B&7&?5%5;5%.;+F?G.-+3"@AE2&?@-G%9'&?%"D<?3%+<-5EC7>06!$=+*5B8BE9=*@H:!$F2(/8B@;*B#07D=F
@r3359
TCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATAC
+
0!3+($B8!1A?%))(6(!H2):=93"H5"-*$D7;-8B-&G*7(%&/0(>/0H2D1G!(*$B%HGB$/CEH?%F'4
@r3360
CAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTNCTTACTTCTTC
+
$G&<42&*>H:05F6?"!!*C&E%/D2B12HG@=5-$09*B,-DC/*5.CA8
@r3361
ATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGT
+
87?4C;B69?=C?*G89+==1/,%D26,1=<D)49E/DB;<C:=*">F0G."4"DG,0!-!4?866'+
@r3362
CCCCCAAGTCTGGCTATGAAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTA
+
-1A3?D-922:*$?'11EC/@+(C;')H)8)(CH4606@4+.,'7)H3B$3;?3-*399C*(3%
@r3363
GGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTT
+
.&?@(E791A!%?,7GA)<7A6"75-%%9)*;(?E:B)"6A:0>>/)5!?-%=-CHD5&*9/D7!0.</7@'H;+$%;/+'&9B<A580D((-.G!4+A*(,3C4)H**A':GF3
@r3364
CTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGA
+
813<"E+=,1<%FC5287D"(HH;*1E*7B<E*D+2B1&*B@=..&"(*>F.%)?3/<@!F>615&C1@FG8<B4:";(5#&<HD7#9@4BCC4;?5(B4.#C.-2>'HB
@r3365
ATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAA
+
&+%'#(&%$("$"#!)#&("+("+*+%)%)"+&(+&!*'#)"%!+()("#$!%+#$"'&%#*&'($(&$%+##%"$#!%($"%&+%+)'%$#&*)"&'%(+&"*%"'&+$'"''!!#"%
@r3366
AAATTCNTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGC
+
82=,>)!9A*GHH2@9C<=4.7)-"A;B14<*F,F1+B,.BBG)',/@>DED2
@r3367
TAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGNTCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATANAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAA
+
8(+5D7:5"%=''B86>FF<-0DD-90+$#<#$'9?*+BD?'FEF'9$1.$%):#!#;;$+G)//,"%*!4&E%>E+,A6,625"9;@#@71,'=8C#"5,E5;;,4?+9>F%529,".9(,A+A18F;*,1&8C,:?FF$%/.#B!GB;0(!)$'!>
@r3368
NCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGNACGCGGGATGTNCATTCTTCATCACATTTAATTGATGTATAG
+
"5DC0F?$7:=!8-.22#(6A-04/@$3H"B;>G()B=G'GHGD?5@B.)8/"E;#"0A1=('8D"3D'EF4;=D7'29/@%(/72)$6+*
@r3369
ATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGA
+
>HE4H+=D0<B1:4$;GD<5*H3E:$=4&B&B?H99#@/#$A*E?D7/!5)GC6A01!#'=+'9?>/A!B0-64'%9"$'@/DBA.G?(FH$@?-2*'B9.CD;#/3703D"A',<3429;<?*,C@;/$A$'G1/)");71F4C%$>C*&H-+DBB)F#CH*$9(,3&)6GE5/(+BB;E?!40)#?2A63A>>6FB((,
@r3370
CAATATACCCGCCTCNTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGNCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGG
+
%E:@#-(F!<9>>C(&'>'5-!,5=E?/EDE6&G=GBA7.&%0D?;;!H,6A"*&HF@7;.)DAE#4*D0@$D)$G@,'.FE8,17>H&<D3A5;9*,=F8D+#*H6E*41@FE,0=5)<<DHA#12@$E$<%)/(H$F<=*@8!C,D$%"*:#*GG"'01F$@A$
@r3371
GATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGACGGACTTTGGCCAGACCGA
+
.-/3.=C9=F=74/<-2<B#F488?D3<G6(A,?;B8G$(3!F258=C>=7!0B251-#.:3=F-!%0H"/:C--.';G/
@r3372
GATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAG
+
E+#C<.2<D#:%CF'"B2<16,%#>=$+4(48A;1D<99:30,(9:A6-@($E+705;72D1)!//DE/38'3@",(2
@r3373
TGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGCAAANGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCC
+
75)+:=>@2?&;)H>2,85+*B8(,$$>!3B8161/$.@?!;'2.:7$@:F8?F7/!)$<*D6.H*:6%%D5C'E8?(7':"%:G74;'?E#F:%'B:'83)$9'60B3F):/A0<&#+8-2:D%!@@F2'9>8?/8D2??)*E.4$GGH=+6('0H.&D-)2"D#-&:5"&
@r3374
CGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCT
+
++)&&'!!)"'(%(!(%+(+#!&(!*!+)$$"$#++&*+#$)*($'"%!)+'!(&
@r3375
TTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACC
+
F;'(BFE7C+B$AF8/</*+!58&))6%"-?2!./-32,@'3E-$C4("*+<21;GG5%
@r3376
CCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGNGTTCAGTAATGAACCTCTGGAGAGAACCANGTATATGAT
+
%B!2F,D6FF<7!/B%>=D'"=<;6.6"8EG>.8$&21@=1;36=D%3<GG<29H<E&/C!B+5$+(.()1DE(>(#*(A59HAF&"1;E*
@r3377
NTTTACCANTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGTTGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCANGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGNTGCCGCACCTCATCAGT
+
$02/0'AF8G?7>G"<(2/=))("%,$"($6H>H7",;/0##D%.=G$AD..2:(6)%%F?8&13#?@>E7G1?!$5$5+2-C,@&>#$)":?7;@AC!6/-H)4@+6G9G;8<(',9)H4H37HEC>--H-E5$4G8$()%1D>84"E6=>+(->#*'C5"!.)-@*:?:C,"A@+/C6!?>>(/516??A2*.4?37HB@15D!C;"B9@@7#=2E"369D:D).A;GEE&*2!,",G'AG8%2;?0<?&6(<)+@,0$>35+.-D7$B).94!31.6%.63??&:$-FE'3175A!>="C5/521'GH&.+*"7*<A%:4%+@8%"
@r3378
NGTNGAACTAAATTAATAGGCATCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAATGATC
+
#%(+*&''"%())&#'("%)"!*+&(!*#(+)'$#%"$+(&'$+)&&!%'(&''%+((&)$#%%"
@r3379
NTATTCGAAAAGGCGGGNATATTCCTGCAGTAGAAAAAAATAAGGCA
+
!&$%)##(*%"+#*%&&*!%"$&$!%%$$%##$+)$)$$'*(')%)!
@r3380
AACCAAAGGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGACACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTC
+
F9*?6&'CE1E=;:+!#5=H?B)5>'8?C3C1%<%"&HE95+!.A$=CF'04D/3B@,#.G1!*?*:4%<B"."(F2@'CF)=!4!%(8?H%3"9&D$5B6C+CC+027#DB&
@r3381
ATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGANTACCTTGGGGCCGGTGAGNATTNGGCCTTTCCGGCAGGTGCGCCGATCNCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATG
+
:,0:4E3(?.:#)(9>@7)&"'>F;)12'2:/6'B&=5&;".E>2&>#85,)5EE)5.'//&,E">+:<?C@!/.F>78B*$C;,%$?8<!)*!C>&@E6F:A0=%.;D?@8<C&)?@AH<9-@*;;:*.=>H@*C.-$&1?;'09$1=.&-30H.D&&0?;D8@/F'62
@r3382
GGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACAC
+
><$6:?,="7915%,C#)=>(###H<+.'DE:#"!:(.>B#)5)AG1C1E:4H@.?B6&5H4%;>EE..3;>
@r3383
NGAGCCATCGCCGTCAGGCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGNCTTCAGCGACCTTGT
+
"(+"*)&%$"''!%#!%$#$"&'')$&)++)'!%*"**++!$**!('))!!#($"%'!$!+*$")"*
@r3384
TCTGNACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACNCGGAAGTGGCCGTAAACTCCAC
+
)$%('&%%&')$+)%%+$+$%*'"#!$$%'+%+!&&)$)'$&'+)#'))"++'!"$!'!((%+"
@r3385
NCTGNAATGTCTANNANGGCANCNGAGNAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATTCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGGAAGCATTTGCTATCTCCTTTTCCGCC
+
#((*#%)$'$!)#!#(#)#*'!'*'"($*+&"&))"+&#+%+%'!)'#%!('%$!+!$#+&&#)*')!(%*(#()%)")+!(!+)!$)*)$%*!%&!+)'+$$(!!'&$)*!%!#)!%&)$%#!"&$%!)"!)*%(&"'%
@r3386
TTGNTGCTGNNATNGGTTTNGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACA
+
!"#"'"!)'$"*)$)*#$)%*+"(""!%(%(*&$)''*+)*)&$%+*%+#!)()#*+'$&!'#)+&)&(!!("$('+*+#*&('%!$+%')&%%!)(%$$'*'"
@r3387
GATANTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCAT
+
>A/HD+73&GE031==*;'D%92:>40G#2%8#(F>>5F!8/A*E
@r3388
AGCCTCATTTCTAAATATGANGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAA
+
0;@283G2&G2B?;/?-'-$G7=6:@3$83AE'-/!3H5:F92A9>41C3(0G##7%8,57D>G,5CG"@"B/B
@r3389
NCGTAGCCNGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGG
+
"+5@1/1>GG@?*7DC4-@0%&F:B4>)CA*E)GF5$#<840*!#B5$0D+76
@r3390
CGGTGTACCGACATAACCGCCGGTGNCATAGCCGCGCATCAGCCGGTAA
+
+BAF>-8&5=.8%$)9*%&.HC2%G=D+H>-CD*(*5):$(?$68E5"+
@r3391
TTTATGCACGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTNGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCCACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGA
+
B&79C/0>*2,)HG4?57+,HCG$(,!$G#3$HE<#?A*+>?C(1H%.=,E#F#)<)?3FFB@&,F86?F4."*&:<,F/!#9&44?209.6,=3=6<:E/GCC3(>H@$-,@F;G/#B1B83#G)<5/91E391G(4G3(F0F094E,8!43&H#1;);%0);4?,*H%
@r3392
TNCTTNTGTATTATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAANGAAAGN
+
*$)&'*&%#)%+!')'%+%!'*'%(((&&*$)*")($%(!!(#"!&$&#+%!&')*'&&$)%$&'
@r3393
TGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGAGAGTAGATAG
+
%;H%6"7,1C.;9G!3,FA(F*>/3#(C3-DE?G>7:A*=$EE;A?4HE,4298ED13)/5&?!29*2$,B>,<:4&=#F3G8&;:C2D<!2A<'-HGB=E)0*=3H!'6)-30"899:>$06+6@>*>
@r3394
TATATGACATCGGTAATTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCNGCGGGTTATTGCTTCTTTCAAGCATAAGCGGCTACATGATACC
+
5C>#/B!/+D'/,,"DD:74D"FBA389(896BF7.5A?=:+E7;0"#G-=-:8>9!><1/@B.!2F%3',:>>@=-F+4G6>424,3A2$,0AD/E,1H/G27(8:
@r3395
TCCTGCAGTAGAAAAAAATAAGGCATTCCNACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTG
+
;!$EHEDF;B!0=0@'310.3"(?2"BH'%1$2A8;%<8C5%&()D5.3G65#3.6GD8%.)-0E$F@@+*AG&=4);,A+2*%$($?)+H+/3.9#EB%1=+CE#($?7/H(C0BA+-55)@A*!9C$46@75,6,
@r3396
CCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGATCTNTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAG
+
7!(AF"'</8E1H=1EB7<"#$B%+%E%4FB@-5C8(1>:H78%"(9<5=/**H*B(D)4-4C/"2@89C!!$B:C5)99)=6&DB3723B1*,9:8=)F"84AC5CC$<'A8C<+;&=&1+;2DG:8H)=E&B07364H',=59!.8/1B(=G@?6:2<@3=E*7H!-5=*%7=9/*,E4).
@r3397
AGNGATGCCGANATCCNGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAAGGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTA
+
&)##$(%#&*##)%&#&+!')*&'%&!+($'%+#($&)!""%+)!+)&#&$%(%)!)##!#)(+)$(*&$*)*)+!)'$)%&'#*'!")*+#&(!)((!+')#(+")&')(%!")*(%&%
@r3398
GGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCTCATAACACAAAAAATAACGTTCTCCACCGA
+
7(##@*2'"1:?/&HFH&-D@):2H50E:</34.3#$9-*3D2"G;*.?/18EDA;-%A=!$,*G,,.A.&2+#$9E*&H#,
@r3399
GTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCA
+
G<8C:?/F1=5<*D?#'35.)6C/:-)#8+"?*<#5/8F0$197!:5G)'&/=H&*($+-*)'E@3?'*2%,%E<&(DE2)19;4G;;9>CD26'>18G9@'+A8@#
@r3400
GTGTGAACCAATCCTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCG
+
="%!;>"*F#B-B9!'HA9!>HAEC/@-9-<+%"6;$F1,=@2;=4,5(6GC82&,("$
@r3401
CCNGGTANGNCCTTGNANNCGGCCNGCCGCATTCTGGCCGCAGCCCCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATNCCGTTAACGATTTGCTGAACACACCGGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTT
+
'%$&'('"&"%)()$%($%*!)($#++)+)#+*'&#%(#%&$('((*(+#(#)!&(+!+%'&*)%*'%)&+&*$"))!%'%""+()'"")'*$"!!#+#"'"%(#+)*!'#%#)*'&##*&"$)&&!)(#+%#+%!&!%)%*'#%#&$!+$&!#!*&((+)!(("!$+*!+'!+&!!)!!+#%!!&%+*)!'+#"#&$(+
@r3402
GGCGAAACCCGATCTNCCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCTCGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAG
+
@!17G3BG3&4HD<$#%C6H:<EFB'66@F%<)-*-=8&0-H(;@<>@*'7%GGH9($E5>E-BG<7?@)4.?5;:2-A<45D*5'CC):1<-E39&6D275F@A
@r3403
GATGNCCAGNCCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGNGCCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATNATNTTGTTAACGA
+
*%)%+*"&)&""%#))!)!&+#*#%'%!#$%$%#%&##))&"'+%#'!*#++)"%$$#+)+#)&)$'!$'$"*!(')#+#+%+#&"&""*""&$%#")&!*'+!"'#$(#$(+%$+'*"&++$!**+'!&$"&*%)+*""$&$"%&'$'&*##!$&$!&"%$%%!'$#)%*'&%)&*%&*#"+&#$"($)$"+"&!*&"!#%"!"#)*!
@r3404
NCCGAAGAATGCGACACTGACGGCGCTGGCAGNGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATT
+
#$*$%+#!)!)$%"))&&"$%#&)+"++##$'$%&+#*)"$+%""&++!*))%+$$")+"&#(((!(!+%&#"&(&"*#('*+*#%('$("+"($#)!*(")#))$&(#+&*!(#*'$+**
@r3405
GCTTNCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTCGATACCGGCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCG
+
F#B&5#5<(,$=%C4)@,8+.',.?!9>:.D@'<()80<#<.:&<=;DA1"(??3+!*!!2@CF5?%5F1E1%*1'))B3,>;,(#C7'B1DC@G"(!*&9>'%B6F;5->7('0;
@r3406
ATTCAAAGAAGCGGGCGGAACGGTCGGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCNGTCATGN
+
+A7:8$*(@G!1/+'C1>D#D,2<!:=H87;#G+;9C6=:'!#&",4??//!7)22D>%9&80C8H-D?38=8BBB5?-H*B>B95G%3>:<586:*":3:>
@r3407
GCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTAC
+
&9%,'"(8610)=@H;F((++($0&!+3@245::AD"60:2$
@r3408
GTGNNNNNTTGGTNNCNNNNACCANNNANNCCACCNNANNACNANAN
+
#$$!!!!"$$$#$$"#!$!"#$#$"#"!!!!"$$$"!!!"#!"$""$
@r3409
TTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCTGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTTGTTTANGCGCTGG
+
5-(4=.,*B@;'7.CE<:7F,588@"F-1)733$26B*>#7.(!!'#@6034!"=3B=(G0#H>+A6G9>.54+EF6.<5<.&"2<D?%E/1#@8??H-;F$8+34EF-4%E2-2446>"G+!A245="98$5
@r3410
GCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGNTTTGCCACGCCACGGTATTTCC
+
B3+66;+!,-!.$,7&,&;'78;=3C*+B/'$F16$0:617);8@&H;9E="7,7+!F+C$AG+=D#/GGC/:1.G7)A$DC.+98(B7@'F8=CA4&())&(A;60!=="?3/4<3C:2!';+F&#1
@r3411
ATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCANCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTT
+
BD<8<BHB.=4<C0/;;0-&*3C!#52-7A%E-8E;G,F)<$-A$2F53'%A,C)7/CH1A;$.+B+6H.;*F?1C;+:3000?0<(1.$.9H0@0C#++3!7C2@->HE:(2"*5>=9-EDB%"C-H5<:2
@r3412
TACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACAC
+
=%@FG233C=H+0-=C<&G=:!.35:11G>(>D+:C8(12H3&%.G,#.F517CB&<22,)E,<#FG6,0G27G%D%/)C#/A;*B9>87BC=26!
@r3413
NCATATAAGCNCGTCTTGAGGCTCAGAGCTGGGCGCGNCACTACCA
+
#%($('!!(!"+'$)&$(+#(+%++!(*&!"()!($++%!((#!#'
@r3414
GAGGAATCGATTTTCCCTTAATTTTCTGGAGGCCACTGCATGTNATGCCGCGTTCGCCAGGCTTGCTGTACAATGTGCGCTGATTCTTGCGNTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGT
+
A;@B>1-=>&8"?E2+@.;A@B7,H>D&%.C"0,E!3>G/7A.$:+%2H*>+GH;9(+H<<<:!&EDE:@D15@G'/7)B*='-1=$6<2D$?88@"E8#+./BA6"G3E<%%9(80A(D#G>&;?%7E,1-H'0)/7)??"10C++(1?
@r3415
GGACCGATTTCAGAANTAAATAACGCGGCGCGGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTC
+
""B/EC$-"/=,A"(A1A<A:<+/F'?84HA*0&"+>D,2,&</'50'-H5/2+>HB8(4=F,*$2H<
@r3416
ATCGTNGTTANCGNGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCANAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAG
+
&*&%*$)!'*)*'#&$+)$%*(+'%$%!!(%!%'*+%&("%%!%+$#)$++'")"+$'"&'&!$$))%%()$*+)*#(!*+#*#()&!*$)'%($+#)!)(')#$&%")")#+%'!+)!*%'++++#""!'(!$+$"%!*%"""+*&&("!$()!)'()*$$$()+(+&($&!))"')(**&%$&##%'!%+$"%%*$(&&"+%
@r3417
CAGCGGNGCTGAATGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCC
+
4;-*3%&9?>/D:*H0:$G8'0E'CB5?7>)2!0@;C0"@/-C3)CE#35<+@/C0
@r3418
ATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCACCAGCAACCCGAACNATACCGGCGACA
+
-!H%>-%71;4C&<--*!(H6%.6783E''E<4C0-FFF<0&!G;"0<$*H&8?:,25@;A'G*',;)040CA6D6491F%G=A
@r3419
GACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCTGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGNTGA
+
80&A?,DDH43>7@2A;&7552&8H$<&$#(8==6)&<B1%9<":12$2,CH:B&):?(6BD?-F2,H*0,!*82A:0AC=F2?EF.?.:H"!"$D!.6E=3H<%,GGE-#1%H?(E3;#6/$53+%!BH(
@r3420
AATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACAT
+
."#E7%:;H*8#*$947/'!0>%6>-#-3-D)'"1/'<4<!;$<G3>-!@?>+,7(>.E("!*'/;)65E6(2%*B7.&0C&5"C
@r3421
CTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATTATTGCA
+
$,1;>4=CB39:,>F-;+8199(=H@?#6?,>44<88'?*8!1!#
@r3422
GTTANTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGA
+
>5@,3AG?()7/BCD-)**46=;DF':E:-+(?A,E2=($*B?<=.%C-#46A.&$=':984:(3%6$G?GEB8>6H4;+1+8191+&7(0A50-8/H(#"DB4!<H/#A*/8+
@r3423
NCCACTCTNNTNCATGTTGCATGGTGNACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGT
+
"$)((##%#*++!!##(!+#$*$&%%*!"(&()'*)+'%"#+%++$"!!$!%$+(*$(!&%%!$&($#%
@r3424
CTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGNTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGA
+
ED%,CF@@A49A$,'*$$8#@+=,1778.4&48HHHEB+?E>C#;H'";./(;01&$)A<;%)),**!EF>**D705:/%(C88D6B)FF#95G:3"H$$'50*/A>1!9!4<$0'9-*G*);B,;G$-6
@r3425
CTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAAT
+
H906@6-D#*43'!D&B/)'#4/E05<>A*!6;54.DC3'2057(:'3,G4H?1(A7:%%9+<B9B?0=D140$F$+;-D@A+
@r3426
ATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGC
+
8'C;@>7;!>B23=,@?"7-A*60+%B'24:>,9B?G%*2FCE3:/-+*?$)H3;==B21;6
@r3427
GCCGGGCGTTTNTTATTGGTGAGAATCGCAGCAACTNGGCGCTCCAATCGAGCCATGTCGTCNTCAACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTTATCTGCGACTTATCAACGCCNACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATNTGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCT
+
F"3D-GG6;'4&FB":''/9(@()B,"B5F;="9(9&H0(H?DH#-36"G)A='7=38%H(BB/1.6(*F4*(3'@1#/@*@#06-5=3A;97!'5EBE"03.?GD#:$28@D!6)C.G*:*>:$@:(CA.$5DH=*A,!F/&2H-&9:,7BA5=F:*<DDAE;28(3%>8?,5):&<F#'&'1#<1%49CF@7"74%<>8'7*.5.3)6&-=*=")?<%17B3'"3B/5H9?;<*!*2)93G.;:$=;:%3/,5!(A#;:/*F=C"H<H(4)C2>>B*!67>7/0:9)5>@;AC=A<-2.F"?G:3H32/@)-64G789(/E+$8-C:F3#227$/5@*!-1
@r3428
CATCTGTCGGTTGTATTTCCCTCCAGAAAGCCAGCAGGACCGCACTTTGTTACGCAAACAATACTATTAAG
+
*:?/+%&9##@,8B%D73./$/E!GA>2GBA87%/+E:%5,E;-,!'%5H,B#&+H/6//H=>H4@0%CB=
@r3429
CTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGNAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCANGTTGCCATTTTTAAAGAAGTATTCGAT
+
6(DE>:/81$6(.75<,9!&E,8!35)G*$512-FD!(63@HA0A)##4H-('HEG".;(=*3<5<)8$)+@7$47?F/>*4:56,%.7%F/EDC*9C%1G710+C'F=@>?!11)*F,==;3#H0GC'0(B74!?.'%+D8=3G!-
@r3430
CGCAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAANAGANGCAGCAAAATCATCAGAAACGAACGNATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGNTCATCTGAAACAGCAGCGGAACNGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGGAGTGCG
+
*(!+'+""!$)))!#%'*"%$###'%$&&()&)#')(!*$!$'&($*%&)$%&!$%#%#)%+*!%)('#&+%!$#&#)#&!+%$$$(&)#'*"#+%(*(((&&*('%&+*")"!&'&)+!%)%$!&($$)*%'$*!)!+((")#!&$!#*%"*+(&&"++*$+%&'**!!+&*#(*$"*("+)&*#&!+#()&!!(("%'&!*')!$*$$)+*)!$"!!'!#!#$$+($!)'!%&%(%($"%#'&'+"*&#&##'$)$&%)*&++)&)%!!($+#++""(!
@r3431
GCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGNAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTG
+
>)+E'D#<2HC8!)F<H4E7@"1-43?)HA=@-&@@H,7G>.677<7B)(1/@37H8+$.(A").)%;&E>FD16=&-,%@AE-FH51:33%+9*#(3.4(ECAH->F@&BA%75.*F?.28;B=0-B!E!F;A%#5G7;F("B:9G(
@r3432
GTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAA
+
9!H'<C+385+%1E3>@'G4A4'"*=AF62C1E8.3C'+%-52E&&/.(7>=7%D.B<?",.C7<A6@0*DAF*/8,3E*FE+E=2>/A-2D'(17
@r3433
ATTTCNCGNCTGCGNGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGC
+
((!(!!$&$$'&!*!(++)&'+"$$%%#)&#%%$+)++$("(#'*+&"+)(+!*)+!!*($+*(%*#'(%%"#%$&'+'+*
@r3434
CAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGT
+
3/7#64F)">@:=*-.F<77-4>G%A92B95'#C<(B3"2#5:0F
@r3435
TCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCNAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCANAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTNTTGTCTCCATGCAGACATCACGAAGGTGTTTA
+
)@4*):G3/.%6A&14>%%#");4?(5#$$%+"G@9/&/0E-)..D:C+D#;&25#"F!!0'.550<,2H;D#+1>888!B(G/F7E#@EF<A!0(;HG:.G+)F#'H(59'*E"%%3"!>741?66(9&=>--#-1*@B.(.E6B6$&@E?:8G3E0!&ED#B4@,#(0>+06AF4<<1<+G+#6!/0BF6G'@A&*'D9<&7%.2=6G).>+1>'-/H04)C>&.0F6"10"?2*:FH&A
@r3436
TTTGCTCTNTGCTTNTTTACGAACATTAAGCGACTTACTCGATGCACGCAANGGTGTAGCAATAATTGCAACTCATNCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATT
+
<@=%"/H1!,#H7&')7DC)?7@>?<%-9"<D>CB6G4&(B$C8&.&+09!3;G$F-"C4,&G?/54F!2.<+;;)B)"6D9D;4A+E=DC0#B8?"A-)&<$E(C&'2D*4!:>7A(C-<?;EF:*9+*06!1.>:)&#+E+,G!.3"(3'H.07%FC@6'<9(0
@r3437
ACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTAC
+
.,4H/;8(0$4//BD3=B5-6842'D%@@).?A)4D0%5(;./7
@r3438
TTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCAT
+
0A8C2!1#B?907&%;G@B&F-G'A==3C??>"@B4GAA:2B,+)>40.C8EE?H3E8FC=!A>,A/&..-@/,9<,/1'310H8<611.'7$8F)6(6C%/-!H'1$&93F4.>0&F;A%80ADB"5*9966A
@r3439
ACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTG
+
4'(002*911A/!6/HB'/(?F>@,*-$DE$;:$G)D#'=*#&:;+*2'AF"F)%:9
@r3440
NCNNGANGAAATNTNGTNTNNTTNANNNTTNTNNAANTATGTCAGGTGCGATGAATCGTCGTTGTATTCCCGGATTAACTATGTCCNCAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTNCGGGAATAANTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCC
+
$!##&%!)#*#*""%%%"&!!'##&%"!(%('!!&!%+!"%*''(#$))*(#+$*!%$&+$+&)$!&#'$&)!'+!!$))#)&$)))()&'%!)$$)%)*$'$#!+%"'(&%*&+*'$+!*+'++&&+*"')*!+%*'#+&!"&%#)$""(*%+("%"%!))"'&%&&&""!")!$*(*+%&"&!
@r3441
AACAAATGACAAGAGTCTGGTTCAGAAGATNAATCGCTCT
+
1C@',HC!/-"7(;1@H71G0A/*)&*+D4,-#/8A%FFG
@r3442
NNGNNTCNNTCNNGNNGNANNTNANGGNNTTTNGTTCNGNNNGCNAGTCNNCNNCNNNNNNGCNNCTCGNANCTNNNNNGANNGNNNNCNNTG
+
"!!"!#$##$#$"$"!"#!!"!#"##$#!"##!#!""!$##!$$!!"!"$!#$"##"!!"""#!!"$##"""$""$#!!"!$$""!!!"!$$#
@r3443
NGGCATTATTCACCACNAACTCATACATNCCAGACAGCCGGTACACCACGTTTTCAGCATGNGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCGTTCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATCGCCNCCAGAAACGC
+
"%0F+"!G3>2B42H03#>/?;(()5=EF5>D$2>%"G>?H'E#:*G-:"<,/,5A4=HBH-(#G6@DE:'#@88/)G"-97=."C.$5(:%3:!E'5EF2D$0:$H>5AC0%&3;2>F#!=GH9E4/48<D)/E8;A9>+'+3BE+<C0C6=45$,"9%6"EE>/$13;C((<D/@#74/.D$#EB
@r3444
TACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACC
+
(=3&461A82C"0,2C''!0DH:)5B'84C);0H>!8A:$$;42-&B%(E'D!1H%A7=9/4D
@r3445
GTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCNGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGAC
+
78&#;-=(.:FB3@C38&2789?:?F(,E>64=57*AG>3=GC&?737EDB7'-1"F@F(=E>D4?E81=<-F6HD"8<.)F8,35#)8<!2.+-GH;-"4#E7'G"!2H#D$H<*065>-">0@7&@CHE&$2G;%:E"5;B><+--&@->:;A%#D>@50'(.$<=(410CB:$-!<%4A,=B3&G6H"G.(/,-)/?!)#$C"38?4)>/C5?3;E3(:8H,;<./.17*+D&",(2DG61''"7-+G7&)@B6E&+7$4.8%&71E6&=)CC-,"
@r3446
CATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCA
+
=6&>!,1;6!<9C''49%H05BE.7&=#)$C0*&,@7,C,
@r3447
ACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCNACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGC
+
&A,:@,=48*G+?%&+%0+G,HB!;:)93;G&-.7>!%1004',B'7#!()0-HD291!$F:E9/6-DH&+8AEF41-)/#$)"4EFD#4-7?>%;,DA%:<F)69EH,2):&%!&"6<8&95)$2-H*<;''@%?H.+$E73119/2B>:DA"':2(H+>E4+-=(@2"-&7!.*)':$CD:%*%.8H'@,<8@AFEH:>1$E6#&7%
@r3448
AAAATCTAATTTNATATATTGATATTTATNTCATTTTACGTTTCTCGTTCA
+
>BE=;)@A"B++4#C*53E?.';.>F<F+@D$!=.>&':G;.61GB00<.9
@r3449
CTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTA
+
-.B7+2.4B=:2C*?9<?<79E25=7+7'>94"G9,)#5-D9+#<,DG9C8#(1C,9$:.H+)-G6#->6@)1<??A"7'-3!DG
@r3450
GCGGTGAAGGGCGTGAGNTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTNCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTT
+
$++**"')'!&+%+#"(++$+&"((*($()'$$+#)")*%#$(*!"!*+))*++&&)"$())"##)$+"*"'"#$+)$$+!)#($"%'%$*%(&(#!&!$%"'%*!&('$%("*)+&)(#+'+)%#)%)$$&#(*%%##!#%+*+)"%)"!($+#)+$+***+!#)#&&"*+&%))(!!*)"$'#"#++!#
@r3451
AGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCAT
+
<3*(=!&C;+-BG-+(&0<3;#//$*"!A3"1"E2D+F?=.$&5+H%7-(1,1*#FG?<7:+4GA5$9F
@r3452
GCCNTCCTTCGCNGNGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCNGCAGTGCCTGGGGGAACTGCGACT
+
)$*!(&"+*'!"%(#!#&*(#%%"#"(#**+)')($&!'&"(&'(#')*!+''+#'*%$()+(*&%!'##"#&')&&')'"&%'!
@r3453
GCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGTTAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCNGNAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGCCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTNTGATA
+
(?@C2DB$:>+5,#9"!D3!@7#F#*H2B7.G&E,&B5.)GG.-1B0B1DB>1F!1H'HF)5+DE7+4*><!5%*3;%&860)&>8A.'*&84,EG52@<16C"21>=!1&,:C.1)%HAE003.-!$3?BG=25/@+;('A'+D=@?F6C*?=3,95=A86-H0E#'?H31GEFB7B2&!%83:!A#+B2960#HDH($G7@D9?68!2&):9*5G6G%#-=$/94'*H5<7.?34/A%H@+=C>-D0GD7*369>1#>H/C:2>4*-";2BA8"&/D9-7;-E-;%-8
@r3454
ATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCC
+
0H$;(8@0/>,3?E4=C$'&/++='7<&*H"%>!%49-(>.,6+63:?-
@r3455
CAGTGAATCCCCGCATTTTATGNGTTNTCATGTTGCCTGCCCGCAT
+
0=8H6@"A*HD/8H,2;G!/%-%F%4*=:'&10>?D)5$HC-="<D
@r3456
TTCNNATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAANGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACG
+
*%%!!)%)'+$+*%)$((*(+"#!#&*"$'!!$$!!!"*%%("('('(*)*"**++&#!+'#++"&+"&&!&)$"+"!%(%+""')(+($#!$+%"!))(&")('"$%)&%$#)!%#%$%"$'"$'+&'+)'**%$&($&'*&"+*'!$&+#&&#!&*%#)#*$)"'%#%((*#')'%"&*$**()!!'++
@r3457
CCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTTAAATCTGCGATGATGAC
+
<G-:'88=C!=(+C+C";",5D35;*&F!-=0@&C1:>:&%:G!0,"!221A2'+.7D#8EH,!67(3::0!=!
@r3458
CTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATAC
+
$7*"(/@;G&&?4"F=>3F7@$&C;E?>$6.>.+#).,FG"6$:<50'34&8
@r3459
AAAGAAAACCCGCGCATAGGCGGGTTCNAGCATCAGCGGCTCANTAAAGGCNATGCTGGNAATATG
+
B&7+!=&==.<C4B7E%E*8D4A@%9A)9$!,2;:CA0EGF'36(/.BGB;+-'9,(>>>,$/16>
@r3460
TTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTANCAATTCATGGAAAAGGTCTGCGTAAAATCCCCAGTCNTCATGCATTGCCTGATCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGATCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGT
+
5?*!>-!B!"-38#D;B5(G!+9>'/%&3#)'$:%!7?(!'F,13&,0:)%4<-0=+H$77,'=)8<308?@CGE-4-@00/98-&+H@7.G;H;)<0"=;#.>'#F@36BE3421!*D+?5;-33<@27(-2A"$5A"3D"=><:'8&H6##.)F8'+C38=8H#5%!BAC"/7*E4>%59+0#<%D8GH/C*ECG%HF#;=(:FG>!H)EC.*7%H&$-E**/2GB*26A2)D%
@r3461
CTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGTTTAC
+
9D)B='%7=,2(8(@#;3FA7E/+>731!(1?=BF(/:H1'=1!8')<G2$:A.<F5'AG58/FC,?.)+!E'$<":G0D:1"!H<).?39
@r3462
TCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGNCTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGNTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTNCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCT
+
@(/&0*C,)4B?>%BH"(?/0?07?%*.$"&6?FE,4=D1BD5,:,"/9;%H(C6D!8*)!;7(;A),(8)0>7!A+%-%&F+HB/"%A6/,+?3B!&5!D>1EDF<&EH=+4?#"(2H%",2$E*6;4H7;>=&3H<5-521?4)H:&?+74-G3*3$8G:B(48D!*/'E0*?!B5>B%35&6'<-FDGH-5,#@(+4F'4=3%*)#=,7+<>%CG,%07.E;##5+$(B9<)D-3*0E=+354/0E:%'@=!G
@r3463
TTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATT
+
>H2:8C?%3D+F!F*@>A:/F?D=3@)<170&+4*=%0>A9HG,=%5=GCH-@>"E/84>AE14F)#1<=67B3.>9AA=>*%BH-+70<&8E8!
@r3464
ATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGAT
+
=4>+FFE$"G/6AG6C&(B)-32*)/6'*F8(2*:3-99;D%)C''ACA;
@r3465
TTACGTTTCTCGCTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAA
+
1&0;.@G)036"0?")G*-/@227=B.:13;8<G9F@*:2C,6E,@:3HD@5#)$'?*#*';
@r3466
TTNGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAAT
+
'"!(+*$%!(())#%)(*!%!&##%**&#+#%"!!(&&#!!&&(!"*'!#&')&*#*(%'##)")$$%)"+"+!)"#!+%""$!!*$%!+'"
@r3467
CGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAG
+
#HH-<9A#D4)$:/>3H!E+,2G=.)&'C7A)A73.2C.9<0G>E.?$C;#D;8&-4:D$7#C#D:*1D466!2$#8(1>+/..:
@r3468
TGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGC
+
)G/<$!?B;G!E(3@9:F=+@E,@/CAH+=%A5%A9-!++-%@"#<;<5';6,B,-$H?6"*68#/0;G.9&/A51(1:;@2G'&5@:?E5@+/';)D$4.H0
@r3469
GCAGAATAACCATGTGGTGATTAACAAGGACGGCACGAACGGGCAGATAGGTCCGGCTGCTNTGAAGGC
+
5-87'-"1@!%/"=F(+3&@$9=C='.5B3?;6E1D-$;8+/A;;>5E'F>;6)=!!5A:?,&G$!#.>
@r3470
GGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACNTTTACCATGATGATTCGGGAAGGTGTGG
+
5+@:9/#ED<AE!.D*$#H%-,()&+.8<$DG'<5'402E@%,$+C461<3/,)C=?C?B5B)F#@/'?,0&H;5%D3"$1621)G#C#)#$9+7)+(?CE<D+@2)..C<6D9(.)+;H$0*CD&#.!)
@r3471
CGATCTACCNAGAAATTTTCCTCACCGATAGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGNACAAACAGGGACGGGCTGNAGCCTTCAACGCGCACGCCCTGTTCGGCATAG
+
@2,(+D502<38H+,/&B><H:"689)3-@=GB$2:,G9840#!>#,8#EG>='*2:F#-%8$F@>;>:.04D?64>D7HFB06E*7*$EC*%/"7-3+1%=.;&:(!@DE4,$-A!(D@,G*47F
@r3472
GTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGACACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTC
+
$1#=)6=B:BG)0")B9<E@6;,"&#+*8"-$!9??>6/<>5<BB(?&)7$"(4$<D7GBG(F@@E@62:=!+"<(.<D41;27F961A%?&7%5*'B5=?@187<28G41981)HG7-"")+**C200#/G9C2135A,;;(?81('3D5G8&#&C0"0*DH2#H$D+C4F+H.,6G&7AH08E@9%0*G&$$GA#8H:?F..DH%77
@r3473
ATGAACGACGTGTTCCTGAAGCGCCTGACGGCCCCCACCATTN
+
G5&9-(=<$%F"/<)C49#0+8)(.H.1*HB9.(!C+>:>;$H
@r3474
ATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCNCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGA
+
*%*=@H.H1A=A<G)*1(-2H:/(C.,C!<(C/*>;A'$+/>(9G=%3:58G(A.D-.!3*HAD8=3$3)%"F-",<26!!.%AD/FGH.4@27<<6
@r3475
TCTGTCACNGACTAAATAGTTTGAATGATTAGCAGTTATGGTGATNAGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGA
+
E+4=C6F.=<9;373.DA?$A=>*8A)C=&,-3F8E4+:5;@E''E"$28(C+)-0#$<7@H37C"%!!0E-/)37$>@%%<#)5702=:%.2$=65%-?13)"E+#C2'D*G%$E8EC3GB477)&;
@r3476
CCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACG
+
)/!?(6H,)0CFA8#=@FF32?:,A9)"DC/C79E!)101AC%/96.9D
@r3477
NCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGG
+
#E)"G;/F9;-"1+CEH3/E<?79E1C'A+#9!AE*+'E(,.2".060+E=E8%=$5
@r3478
TGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGATGGTTATG
+
$H5D2>B,C6/C""79=-+"%!-D!12:%*%B%!<?%H*GA7HD!?@?"F0"6,A>@<:D)+F1)E+=3)6*>8$G<*
@r3479
AANCCGCANATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTNCCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGCGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATNCACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGA
+
ED:A?E7>91G2?9?>"7F/69;0$-+4'?)6'3H32!5*@;=%?82:?<"A#>=@G.6>.H%<69"B1BG,:C$6%A/@93)E/2.F13='#39G7-/;HH#0+;D>!,?B/40($4@?%8(8E621507$9;9,=H@*>1*/9B#/2?+'CE:32B!462B',D*/F3.8'64/D(4+E#A;F"=*E-?%#48$E@+25E.&H,CB875@1-1F+16G>(H,+<D/((D/65>($5(='0H#%H**ADG!0H
@r3480
AANTNAGNCGACTGGTCGTTCAGGGTTGTCGGACTTGTGC
+
*'$$!&(#'*"+%!)+$*'%++#*#"')$%**"%)$%$(%
@r3481
NTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCANAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTA
+
-#'@;>B!600)/$9F>D2=/>$"EDA.'!27*:,;-7C4,&@B*E>00'?!4):=-7?,#2%84H=?7-)75CB953;#HD=':EGC+H3?.*B5&(E6C(0C#7/?:@7<H0)%326=582&H4+"A=5B1G?;;,+!-=4=.19%5+">*@GBH*'2B7$=
@r3482
AATTCACAGTCTAAATCTTTTCGCACTTGATCCAATNCTTCTTTAAANATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATC
+
)+*'%"+!#!+&&)##((%+'(""'"")(*!!$"%*")$&%"%*$"'&$%'!(!(!#!!)$$$!$*(*""'%#$)!#&+#((%"%**#+##%)$'#(+&*%'""+++*!*)$$+()'+"'
@r3483
GCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTC
+
0.G=>HE3E3HH#!$#$6EC&'5;1;7>@%,'$?,EF8'-8>6.?64F=9$07."7100*9.8'865.@)#-A'+C<%19)FAA+)/>.A-0'1*=,+%+F84/GE;88"CF$4F',:@/.(*&E';C5;6&>4?3
@r3484
CTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGA
+
-6%D?:'<3:+7E)6D!>D-AD54E@>-+G-2>.1@CH3)4)&8F3?.C<%27<C825
@r3485
CTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGGTCATTNGCCGCCAGCAGTTGGGCGGTTNTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGC
+
('+%)*!+)"()!&%%'$*&+&&%$*&$***#*&#&##$"#'(%'"(!(+!!&!+$&')()#%)'%'$+'#)%"+("'&+)$#*%(%+)(&&%#++$%&%%)%&%%%++#"&+)"*++(*&!*!+"+**!'*$(''#'%&#)*'!''&$$*!"%%'!"+&#$)
@r3486
NCAACNTNGGNNNAGAGGANNNANTNNANAGCNNANNNATNTCN
+
$$$$$!"$"!#!"$#"#"#"####$#$#!"#!#"#!##$"!$$!
@r3487
AGCTCGACANGTCAGTTATTTACCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCGTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGNCCATTTTGTGGTGATAT
+
A*$25(#<1(*=8:1G#-7>.C8F=)DB+?1A%00B0:6G!#<%C6">'$0./%-(G>#3#,H&812F'883.(9H2A-<1'-+*64BF#&:?'F:6H2>%#!.;16&1*-=-%E5H!!!2D""<H,+7055!!630.2+@0+?#@+!2B.(C2+7;/?)?D!95FGD)-,CD9.5/?BC(:,8$/7"?"@4+%>==
@r3488
ACAAAATATTGAGCGGATACGGCCTGAANGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAG
+
+;B<#FAD?&D0?E</&EH#9A2<DAHC-E!0+6=3(/?(D>$.G1=D#?9<1D+%'3(#(
@r3489
TTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATT
+
/4;+E:E2#0G<9E=/:C69CA5>2EH'.B(>9.GC;H9+<!36)CB#:@!!'28)*;+;!9$%0=!4'D>)&9$9DE
@r3490
ATATGAGGAGGGCTGTTTTTACAAAATCNGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATANCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTCCAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAAGCATTCAACACCCGCACTCTCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTT
+
#")!+")+(%#"&#+("#+&)#*%&()&+(&$+#+!*+$)&#)(#)(*"'('#$(')#'%'+($'()#'&"!+$!++%"%*"'$&%$*)$%(%+&'"$$"+&$"&#'+")''("#+(!!(#%*(!'&%'*(#$+&#"'")$$$*$#'&%"!%$##!*%&'+"$*'+&%(#)'"+'+"(#"($'*!*&$+'*$%&#""$*'!*!+"$""%#!%!)&*$&*&+*%*"&#%!#!*%&!&$)!'+#"'')$#%$'++*))$!%!*!''#$+&($(""+*)($%)+&+)*'"$$+$)#%**%*!+!#%"")#'%#"%*)"!$$'"+
@r3491
TCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCG
+
/(.7-BC!<6(/"@5.@9,<-,&G')1A(>%=3+(?-.@;
@r3492
CTTGTTTCAGTTTCGTTTAGTGCATTNGATNCTTTTACTCCTCTTAAAGAACAACCTGACCCAGCAAAAGGTACANAATGGTTTTATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTT
+
-FEGC06(:1:#%$:HG:%>;<@AB*2C,B05$9?%?@=;G<>AA;$)=:1765#65<.?F'2#/A8$.?'!E;(::9>B=;0'>7?4,'A!8)!6B)DE*2+B5C#<H0+%<8G?0/",$1.4!=,;F6&78G(!1,5086G
@r3493
GAGCCCGTCGAGTATACTGGCAATTTCACCTGCGATCCGCGACA
+
@==#&=+DH</':*#G&C@&7?,*!%;1:H9+A)('@9:,=C(4
@r3494
GGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTNTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAAAGCCTTATCGACATACTTAATCAG
+
<A)<9BG1$*'#A2=0H"!H>!;6!%+(2)C2&#A@;A57E:G87+>F;.E1)F:A=518-E))<(!%>;<)8'9&/"7@:*2'/6E/G@;<FH?-G7
@r3495
GCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCNGTTTATCTCACCGGCGCTGAATACACGGGCGAAG
+
;;7760F:4)+?<D'+B8#D,H(H-28;-/>*=F0"-AF*A*H6H5#;-/BE<D,F2(6:6+C2-?"6/9
@r3496
TATTTCCTTCAAGCTTTGCCACGCCACGGTATTTNCCCGATACCTTGTGTGCAAA
+
E#-9!D&>5#A*>+9%/G!<&:,9-9)(2&6F."344(8//6$,E=@'(@47$/B
@r3497
GGATGNTCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATNTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGT
+
("&()("+#(%)*)'!"#$&#+(#'"&%$"'$"))%'##")+!%!*'#+%"!'%"'+$&(&!$#'')+&*"#*)((+(*#$'(%#$+!+"!##)%!&%+!%+('&(#"%***%$'+#&!(!%(('$*&*+#'""()*)(+
@r3498
TGCGTNCAANTTCTGGCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGNTCTTTGAGTTTCTGTTGGTNCTCNGCCT
+
((''('$%#"**(*&!+"&)$%&&$%(*$&**%!%)%$%"#*%+!(("#!*'#+'!""'!!(%&#!*(&&'*!'("$*!+%)+%++$!)"$*&!$+"!!&+#*('$)(#%""))+)'!&(!&!)$$)+
@r3499
CAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCCGCA
+
89"-=93,%5G34%5=#D+%A)G:<?"16$+0,>C#;,@=
@r3500
TGANTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCTA
+
(=774)5FG"*>/A.E'*%2+&AF8--AADC*2G5/H8."$3!"B*>F;$++=26E=#F<*A?.>:3"'E4#1!"(+=/9$&821>4*"10&'FC=9BB<6F-&?*G!#2
@r3501
ACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATNTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCANAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCNGAAAGAATCGGCATACCAGGAAGGGCGCTGGG
+
+%&7241/G?FF@08*6!.&-G@""(-5.#H'#F%'9H,(A4)#.+<'06)-:6&+2;"G:1-*((>&;7,E,$2+#>2,>*41.F)B!E1C%81+?9B7A<"2;*FG;710B=.3B.1'&.$>%1E7<%CF<#1+%/")><8;6B;/-$#245$.B7-&"8.($C2?
@r3502
TATTTGGATATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAAC
+
"#.,G6(&2F%/+A-$1/7-AEE1><!B!-1,-52$(/5(?48G+D79;!2'>;:4A3)
@r3503
NNANCNTACGTCAGTTCACNACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTNTTCCAGAAACGACTCCAGTACCGTAGCCTGCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCNCTGAGAATAGCCATCACCAAAGCGCACCTTTNTTACAGAAGGGACCNAAGC
+
#"'%'$$!#"#&')$(&*'#*($+#+$(%&)'$%"))'*%))*!&&))&*)"#'!)("()!$#&*"'###+")*$"$&*#"%'#()'#'"$*($+!#'"+#"#(%%!%*++("%!!)(!!)%*!&**&$($'#%!!('!%&#**#$*&*'"+$&%$%*+)+#$&)')%#%#&#)#!')#&+##''%'+$%"#$)""'&+$"+)*$$)(%"&$$%$#&!!#'"!'!&'#'!$#&$!+&#+!&"))&$!)$!)!'(""($+'#'&!%#!%!+($'(!''$%!&+'*%$(&'""$**#"')
@r3504
TCGACATCATTACGCNTCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGA
+
9.B5,AG'/1&*)4<)$)>>;%&*6B'FH:BD9*;1#2>-9@!H7B@@?:78'-21*8:/"A@678=/=C#2B1E,H8&(-8*2"='(HD6&>G"6>9-*-'*440,CD5573#H+?4*%8-(0-8%7;=*(8-EBAC$A*G')(E"FHD3-'@51=9F'09-4F%34$.BG
@r3505
AACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTNAGCACATCAGCAGG
+
/9/6*H;9;(!DD).>;H@GA?B6&(G-H0HEH76&A0)CD!4H=E8*1:>:=!F(72)5>,/8HB6HFH?C(1?#E%
@r3506
NCCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGA
+
!3.?5D.),='9(7'@*<(6FF(#BA*0)C:(:G/&1:,D-C@)-*)4)**H7:&5'G"7-D#E,&@6C:18:H%D/
@r3507
GCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGNGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTNCAAAATTCAAAGAAGC
+
/28=B!,%+-5<9%H0A0AH1/)4>99<>+7"(%;9#=0*0!5B1;/;D.*"&/<!7(2&:7?9$5;//<A1B8H'!4;?B6C%)=:0A0%@=&H5G!2HF?*98.56+=$86>'57)4+>68.G+6($5";E:DG1%0F/$"3#.&9+BHD=+/0)'35F6GH)/57/"<A(&#,)4>5B!!@C@7GG2&#-C;$+DF*C59G+./3;D7-.-#-F(6184"(E/4(@9B!'@03%<:FB&(2&3,A4E,B%#=F2&CC10%D
@r3508
ATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATNTTAT
+
&/*"145F%"9+7&7-GDFB=)A%8&?9H!.>?)B62AD/&*"G90%GD=55..)9FA%%/
@r3509
ATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATNAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGNCAAAATTGAAAACAAATAATGATTTTATTTTGGCTGATANTGACCTGTTCGTTGCAACAAATTG
+
7!2*':HA:B/%,1')GGE%7:'D=&4*"B'E7-:%)61/@@9=$0==;7E.?D=!/=EC$/0"'D47)C68GC%!45.?91:36'9>,)@FB&0F%+=4<!HEC"FD3=46&31-/'%A5C+#/)(.1.!C?,3*;361?F29AFE!A"::2E7D;3H(-%2)
@r3510
NAGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCNAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGC
+
%"+!*#)&%!#$#"$&$&*&+)%'%+('!$('(+'%$*#&&%)+(")#+'##'&+#('!#))&!%"*++%#*#&(#&*$''$*!#&"&*#)()$##(*"&"%$($+"+"#%$"#(!$$)%%+%&#
@r3511
AAAAGACAGGCACAATCTTTACTANCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAANTTGAAGAGTTCGAAGAGCATC
+
G%;<+B5E+=<!>:#HH34H-.:97!24*()&+8,'>B?'7<)*<5<1'3!2B82&!?:<+BE,)-1!/0?<"H,%2/9%"DBH
@r3512
GCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAANT
+
:="@E&E;4?:7-H/H9%+/7!."E,E";7)FH5"1:3#:4:
@r3513
AGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGNTGACACGNAAGAAACCGGACGTTATGATTT
+
5D9*+,,75=E=2:.A&D=<C'88A2%.8<CB7B*!+<?HDH$"G;0BA5-0#!*=7C0HE@7/:ED'9.G@'@H'
@r3514
CCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATANCCAGGTAAAATTTTCCGGTAACG
+
9G4)?D:D"/"?/5EH18;5"739:6B%2!@1-F/)D"A5%'E317>A74;*96:6:8(F;"9=(2;>6#0(:=.6=H347G8H)-B?2C)A;553:&<-5/@F3<;>6!3H6+>+.=-H??;+,'1-+<30/43E-&<D!%*8)$37#B+')=44C)3">!3A#7G.1C:
@r3515
CAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACA
+
89'1AC(57.(@,#/#G*'!!*H#B/4;8#=6C3()'H@D#5FBFB'.?-(;B+%&21*(C@$GH7"65338C.-D2FH=2D:.="8?>$+5$3#)99)6,,<-((&@F<F*2'@#C"<HF<#*+.(5H5026G@E-?
@r3516
CTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAA
+
+'#*$%($(!"!+#'%&&#%"%!#)""%'+!(&+!)%*&$(%
@r3517
CAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCA
+
3511A/9<4.690=3%;"3!&7,D(41#7'=+0:&;*B7=9!>578FA*84H+8H9AF$4<#?<D%9D=@*;**$D-:?2G'F63
@r3518
TNATGGAAGCGTTTATGCGGAAGANGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCGCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATGCATTTATTT
+
)":?)"''1>'G,<3;;$$'"(96#&7H7%*+53,);<0,2:!46-C:!8F@'/F/HA-GC50!-<77$0+F5'"E)-":=!):?*1=7F/9A=6@E:#<'.0G''5!;C%(/3,7H:D4E%.G1B$8,G-61+,
@r3519
TGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGAC
+
9236.*E2"572?*F0)&HE>E%C;,#)&0G'0%GCE45H'B('G"3FD';*.(5&19>8E#F;E*4&HC(>.%GFC?%A*==;7)/6!8+."+
@r3520
NNNTTGNCNNCNGAGCNTNNNCGCCNTTGCTCTTNTNGTGGANTCTTCAAGTGGAG
+
%!!$*!&!!!%!)#*(#**!')$("!&$!#)"!)'$"'%$#"&*+*""(*"")#)"
@r3521
GGNTNCATAGACGAGGGANNNTCGGTGTCANACAAGTTAATCAGATTAACACTGAGCGATTCATTCCGAGAGGCAATAG
+
($!$#')((*&%%'&!%&!"$&$'("'''(#$&+$+"%&"#"!+&%***$(#*'!("'*+)"$*)%)$%"!!(#!!()*
@r3522
GGCTNNNNTCNGNNNCGTNCNNCGNACNNCCNNAACNNNTNCCCATGCNANNNNANATNCNNNNCCCAATGNNNNGNGGTNNGCNTCGNNNNNNTNNATNGNANNAGNNTNTNTGGCNATTNNAANNAANNCNNACTCNT
+
##"!$"!"""!#$"#$#$$""!$$"""""$"$$$""#!$$!$"$$$!!$##!"""##$"!$!!!"!!#$!!"$"#!!$$$""##!###!$"""!$#"#$"!!##"#!$!$!"$$$$$!$!!#$$""!"!#!!""!$!"$"
@r3523
AGGCTCNAGCCCGTCCCTGTTTGTCCGGNCTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAG
+
;D)63C;C&>;;5:&0G9EAH*7,181-?2E+@9:G)8/@,@2/=+6#F/453HE:E,41?D<"-A+.,B(/A,!;;/6
@r3524
NGNNAGCNAGGNNCNNANCNTNTAGNNAGNGTNNGNCACTNCTCAANTCCNGNGCGTNGTCTNNCGCGNNCNCNCGNANGGNCTNNANNNTNACCGCCGGNTNGCNGTNATTNAGCNANCCCCTTTGNNTAGCNTAANN
+
"$!$#$$#$!"!""#$!#$!!!$#$$!##"!#!$"#""$$!$#!""!"#"!$"$!$#!$!$###$##!!$""!!#"##!"$"#""!!"$""#$##$!"$"!$!$$"!$#""$#####""""#""##$"!$!""!$$!$!
@r3525
TNNGCAAACNNGGCCTGTNCAAAAGCGGTGTTNGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTNTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTNGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACNGCTCAGCTGCACTATCCC
+
'!##)')"$"')"%($*&"++('%+')""$%$'%$$+$('*+!+'+%'')'!++"("+#"!""')"'%(&'#&)%)&(*&((#")'#(&#%+#'&(&)$))%)%)(%**+!+$&*&(#!)%")'+%&(("&*!+#'&'+)#'+$"$&#(++*'&&&($+!%(*'*)+')"#+&"#'(#%++$()()%(*()!&"#!!$$!+(%&*(&+"+$
@r3526
NNCAATATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCAAATGCACTAANCNAAACTGAAANAAGCGATCGAAAANATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTT
+
!0.!;!&B>F"G<"'16<.E)1)+>"<;;-)G6G"%B:0A"DB&-2D<0=E=%>D+:D,F437,:&473?+19%6)C2@?<"C(H(G78H3+'!'->(3/0:=<BC,1%:2)&-/+'-1'>6A99G-A%E)74.0'#G1+93&H
@r3527
AGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGANCAATCTATGGNTTTGTNCGCAGCCCTTAATGAAGGCAGGAA
+
:;B9"E,9@C)"A'&15G1-=$614#-92"G4/"/;3:G3H2A%;43;0AF5//E<&5&B'*.9%2'71$,?E5B0.F=*08)1&.D(8A(6>E@*<2,#8=B4$G,;,$H+=B2>6%
@r3528
CACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGGTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATA
+
<E.H<A&H(:$9+8$;B><)B243$+G9@!73$$'?007:.-23(@G!'2?@47)!1G=CB>$0/E91C-8,9$4>8.A1&>3E0(<2,C+$-?*&,#10;.F=*14+7&5A'!BE<*"0HG3
@r3529
ATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTT
+
>,/8->'!?E4.)D+<@=+.G*%=D90;'D,3B%3AE5GD".389
@r3530
TATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAANAACTAAGTAGTGATGAAAACTTTTCAAATATGGAAC
+
<&H8;.)'3>*ECC':'37+B<&#'*04<CE%&%.H$A3G!)=@,:249;$#F:H7G(6<A()B&GE7+/A!)B'+*GG:+(@
@r3531
ATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGATTATCAGCTATTGCCAGCGCCAGATATAAGCGATTTAAGCTAAGAA
+
G.3H@1D6BF<<>.<4,4<-(A.618&>!=2&=E::7E'?(;5G(F:+D*(90+4D56@51;+9'3+9F<:A<0:$#6><=)C*<,E'3=!9"(*'/91C+C67",2&FC6@B<:?&0@CH0$-2:
@r3532
GAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTC
+
/H'EC5D@*3$,$;C'+%(.;!>?"A?3-;+>':2D01:(C$+B0;15=<>A6-&32#<5D4$@:B@
@r3533
AAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCTC
+
HC$(11>,:0#(%)5:B<'A5>.B+)>)2%E'*76*H2D-:'6+'.,+6@6B&$170B&5+9B;"G
@r3534
TACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGACTCTAACTATTACCTGCGAACTGTTTCGGGACTGCATT
+
%(+%($&!!!"'))+&'%'"''()*%%%&&%++)"$"$(&&*(!!("'+%#%#+*#'"$#'+"$$++!$&('#%&&!('#*!
@r3535
TTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGAC
+
.<D!!(@>C/(&'/G87-=%G%F3283FEB#/;/5C@/B=A@89B9@-,?7$D?(9AD>CE?24>:D;*&,,B8<'1.*B75
@r3536
TCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCNTGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGT
+
&C(59&(2E6!CC#@;='>;77"H$A/>5D+CE&5$(+('7,GA-G+E,#/AA)-1B$4@C1-;=?"1A<0H6A&.$"F?;&D&A?.@#%H.H73@4%;?/7D34)5%B=*-6)5#G,.!3A&#+C)=8A#>!/&!<@"'@F'+5,FE)%D!A59&2DF$.*F
@r3537
NGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTNCGGGAATGCAGGATATTCCGACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCNGTAAAGGTTGACTTAAATCGAC
+
!++"%'$&)&!"+&*+!*$$$(!*&#&(((&''%'&!)&!#&++"+')'!&)#+%*%)!""*#)*&#'!*+('"'&)"#&&)($("*"&""$")"%))(%)''$$!!'&%(%(&+&!'&'*&+*$('
@r3538
ATCGGTCATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCA
+
<,C0!+<*$H4.<+)6B!(,/#A$!5?E/':*9'+5&8@5#A(::@9(&:HE0'8/H;*
@r3539
GNCCACGATAGANGTGGNTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTT
+
!"##)*$&$#*$+&#*"(&"&+!$()'!")#(%$$(!"%$$'#"**+&(**!$)")'&#&#$(&*(+*!"'$*'&!!)))&&
@r3540
AAACCACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCTATTTTT
+
6E;3+H+"2B1-:5*F.-<=6%)6!#GD?@;2:8-C-FD:4A2=#H;2
@r3541
GACAAGCTCATCNGCGGCCTTNCGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGC
+
6'C0/=0BD*F8/>/*9!&&>--CH4:G%,;G#"&8""@;,79=%,72HH$.080<F&G':E!C%=#6!D6/)9%,'>+&<;96E
@r3542
CAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAACGCAACGAGGCGCTACGAATCGAGAGTGCGTTGCTTAAC
+
/&B5AB&8#/D-*.1;>#,3:5%!>B8#*B2*-)B-E'1+4+=,.4BCC+2#0C)/66,DD#D/871*H,H-")#6#*#>3"(<513&E
@r3543
TATCGATATACATTTGGTTGGCNAACTTGAGTGGTTTCACTG
+
=;D9*81%F'$@,E!F9&@E#=!@C;??70@2)#:H'H&58;
@r3544
TCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTNCCAGGATGGCGAACAACAAGAAACTNGTTTCCGTCTTC
+
5=$'H$CHC.>?8:;!=)/&->?#%$A49=;?+-<67;-+2$+1)084G)E(?5#>F,+A9!?2>FG;*9*$-;%BC)'#
@r3545
NGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGNTTCCGCTGACG
+
(8(#',&E'3D3=$9H54>%+%=G9F;=)8.0D+>F=3;%*8E,FC*537
@r3546
AATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACC
+
AD02#2+G3@B7")>G;62)C5662=C63$?%?%7;"'+5E5"34CDH8D?9,C!D!>/C0H"!)+:F.3F3&)===01*(">:*(%$=8H.52,-BH3:)1CA2@
@r3547
GATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCAC
+
H2A@?A71B7>9"0B&"'/CE-#6-3*:*+2;%DC((3@(!#8*
@r3548
ATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAATTTAAAAAGGA
+
>!&E8'F7EHB#;4)&+*1$42C,6G0"H(D9A=+@@A8;5+7DD<7,%264AA>C&A2G&%?C(-"%F=9F,+-%81@67?$:
@r3549
AAACCAGCAATACATCAAACGCCNCGACCATAAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGANCAGCGTGAGTANTACGAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGG
+
?$))56:?;7"(BA8A>,5H9)>>3",HA*F;25@2;6A8B9$'$>BD;8/944:B@%&G=A(;6/F;/9DF'20',(D(:H24G<+$7!/&"-5=5%=3;>%!?'@%8@=D33,!=)*.;F4;"/#2:=%$0CC<1.F#H14;>*5GF,:<B;1/)D%><D"5
@r3550
TGGAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACNTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACNG
+
*+($'#&**'**')"!*!"!)!&%(%$!+'''!&(%)!+"(#"%&((*(%'$#%((!"$'')))$!#*$))+"'&(#$#!&$'$'!(!!$$*%(&"(*%'&!*%"$$+&%!'"!*'*(+&)"
@r3551
NNNCCACAACNGACAGANGATNNTGCAGATNACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGT
+
*!)%()'(*&($(&!)'"'$&"#+(!"+&%!(%*&#!#+)+#*$'&&!!*#+)+"($)!(+)'&*!&%'+"!()**+!!%!%%$(#
@r3552
TCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCNTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTC
+
+&!''&(&%"'!!+"#+*#'!')%%)!"+(!"(+"#*$#)&"!&&#"!*'%(*("")"##$'!*%"#'(!('!%+%#)())!!''$+*+)#**+&))(%)'#)'"&&'+''("%#&#)*")#
@r3553
TTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATGTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATTGATTCAAAT
+
:D0H@5.'83+66-4&#<=")5HH>EG>8$'4/G6#<0/D5FAH$/)4+E#-<*>.BB13@F(F4'4:F'&78%>A@509&6C29/"+5-6(*8D"!8!$+*&9=!0B"3@/@H:<6>18H*=&8C<;<'")H'5#(=E%@&#FG&E-"BAF-0;#2!0<G!#!4:&4<-D.(>A;)#&/A$
@r3554
GACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCC
+
2$D1@0;9A'92%@5H?4,8,7(!/#+C221.3*+>G2>4%)C8#*!.30>
@r3555
GACGGAGACNAGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGNTTGCCAACNAAATGTATATCGATACCGGCGCA
+
*!)$%$&%#)"%$++'()%$%!$!(("$&)$)(&%&'"$&#%(%"'&('++'')%+#&(*"&+*#'(#'!+#"()%(*'(!+)&
@r3556
ATANACCGAAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGGTGACAATGTCGCCCCAAGACCATCTCTATGAGCTGNAAAAG
+
&(#&*%*+)()!"(!*"%"++*'%(*#!&$#('**!"+"+(*$&%#!&!#*&%!$'%)'$()+*%*$##+%'(%!(**"*%*&)"&'"(++%$##(#%&%#%'%#*#$%)*&'+(&)!(&"+!%$!%(*(("))"%*'*#"&'&'!!*%())*+&()*)*+($)+"#(#!"'"%%$'")$+&)'")""%$$&$&)*($%!!!*&#*"!%)
@r3557
AACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATT
+
4*&9E.9D(G&HH(+&>H1!*3H'4.7.;E!:12)-$"741$*E(33(;>*"0G6/$06B6.!$&?)?<-5%")'#E*B@2!F3E&H>;9-(.;@,80$?'4<GA</*E9589C&FC%3.98)@880&%-#'F8(7@7?'$<!4.+?4?7*2
@r3558
TGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAG
+
1'C2BG;<GD,2&=3<E<HE3=)2(1F%B((G2@A+G80"EH819H,91
@r3559
CTGCGAAAAGACCGGGNTCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATNCGGTGAAGA
+
,(:)14$2=3G<AH:F&"!H;@D60)"38?C#!1%)/1:>?F(B99DC3=6.*?'$?8#%4#?
@r3560
TTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCG
+
5*!B-.A;!&4(>/G8;B>70A+A.DH!-@:H"@&&(/<@C'F%<,:5>/(B@91-61"6G7275(H1>&7CB$1<DE6?0.#0:7)%*%>EF9
@r3561
CCCGTCCTCGCTGACGTAATATCCCAGCNCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCG
+
<:!2,8#A"&7G7481:/<+<(F7?28H;(F4&(D*7;715*#"4GA8,+849!1"3<@(+;-C5*1%34ED5397$>57-*
@r3562
TATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCNGGACGACCAATAT
+
8'(E.?7@%"8267><#3?CC34;.'=&?*C?G1F>=*&=C#54<*"4<2F&650"!
@r3563
TTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAA
+
7-E-%"C0'*">+,5F;%?*;($=#!*.:F7&?E>!&;?$53BB!7242B
@r3564
AAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCG
+
B+'-)83*)*$HA3E1&3#D/>8*E&1#H72D"5>-0)"3=F*8.4-"2:"!D&A;5'0-0G-$:EB.7<&+9GC54A=G@69#+:<*;@:78=(1<G:"4;53*$F6<H-(:)6!>G*!/0<>3!?23'H61B>!';+*=8E<FEA.&G06?)E)B*((,$%24*::5,3E7F5:4,H&>>0F)&%&#-)%43D2#):#9-.7A-&3<$A@%F*9=02
@r3565
TTGCCGTCACTGCGTAAACNATCGGGAGAGCAGGCGGTACGCAT
+
%5</>6C>/;A>87!D*4H,??!&2%6'F-&2>D,0#9;/DB'=
@r3566
CAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCCCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCG
+
,33--3C5>?C6$28%8.)5G94,G.*FG?/0*(#?,*(3%C/*(+%>$.=12,C5/*/'389'*B<AC#H,8.@75$C"?4=!()D><"20?FC"@*B#$'72'95DE)B4C/44&.@7734A!/1$76E9-(54
@r3567
AGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTG
+
%::;8%/EA-7#87F2?;/=7+/)-!B/C"9D,$H,D+?E)22F=%&,,!57,48-#%F1"0*1"B
@r3568
AGGGTATCCNGCTGCGCTGATCCCACCTCNTTTTCATGTCCGG
+
:/B>/?/&+/!$?@'0:/'2%11590!0++!+,(39@.:-?<(
@r3569
CAAGCAACAGGCAGGCGTGACAGCCAGCANACCAAAACTCGACCTGACAAACACA
+
+)&*!*%!"##'$)'!"%%**%""%*%!"#')"+$$&#)&!$"'(")+'$++&*'
@r3570
ATNANCGTNGTGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCANTGCTTTTTTATAATGCCNACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAANTATCAATATATTAAATTAGATTT
+
#!!'%$*()+#)&*"'$"$%)#!)"#'*(!**(%+')*+#('#(#%)$*!("#&+)#!#")#()(#&)+**&$!&#(%"&&(*%'("$*+'&$))'*'!)+'"$((!+%!#("*!)***&'(%#!&'$'!&(*%$))*%!$+)$"%$+"'+)'+"&#!#+$!$"&+#)%#(&+$"'*##'!*+%!*%+
@r3571
CGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCCGCGACCAATCACCACAACCTGACC
+
/*41CCHB/:,14D=F/,AG5D5&*9):*!2;D.?;%)88,)AE@2:<(-68%7#/!0414A';992*'':(494@&1(&91;)!2<6*0,'*$7GA1!0%?0?1/C7*2.!30>F-3F$
@r3572
CCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATNTTCCCTNGTTTTG
+
+!+!#"")%($!'"!('%&))%($+($#$"($()"*)%%!!'%)&(*+&##"
@r3573
GGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTNTTTCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAG
+
6@6%9&+45G#E)@"0.0)-:H><*6("DH;%?A+@7<=>61+E#*$;:H.>?G7(&);2$C?*#!<C;)H*=$;F,9G.*4,=D6)$A>;//%7H'ECD0)F55$0''DE,$.1-G>
@r3574
AGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCG
+
H:01F3,+AE*1$!7,*.<;9/HC3-C#D(D/7&$%#4477=!E*<2-1%<D
@r3575
CNGATGATCCNNTNGNTTCNNCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCNTCGGNGGGAGGCTGCATTATCCACGCCGGAGG
+
*!')!)(%)($#&%&#))$$"&%*+*"$'$(%"&!'"(&*&&!')+**!$*(**%)#!)!+$*#)#$*("*"+(%'!%'!()&)'(#(&(#')$)'("!!"#!*(#!*))"#+!!%(+'&&(*'!&&%%'
@r3576
TGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCG
+
@"9G;B%33)?F&=4A%0*=&5C</-69EHE4;!*%>62*#/!35G>?/.,<"3A.%D.3.D8:-F1H$,?#;/6
@r3577
TTGGTGGTGCTCTCCAGAGTGTGNAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGTAACAGAAAGATAAACTTAAGATTCGAAAANTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTA
+
)D1(H'!7$6(,4*+*5@&?=FG-A93@%3.)1#:+<9<28@$7@";+@3,>)-C:H%>7H%:C34&+3A"%%(D*#%?26%(&"B9!@42G/=;7?+57:!*&=8)"CC!(8G;"A:>(51;13>75&7'61=%(B'C(#9*.G:GB334!0?)7:C33#;*H'+<+H501+&C*!63?H801BD8-+HB5").)(!63C)4!<5/+F+6&!-1<4>4$G&)2F06A91
@r3578
GCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTT
+
CC$:7,'&5CE:'6)3FGF6-9$9G=9>E5,H6!G06#A#0,,60AG619;&4)F/AC1;+(D@*:0B;!23<+>@+6,"'.
@r3579
CAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCNCGTTG
+
?5<%9??/0AB6H.E#,+-#C%=!6$@,*@.H'@@G+<@"-G1+C5G1:&C'/$,E2E8
@r3580
AGCGNGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTC
+
)*#%$'&&%+&&(%'&$*)))%%$$''*$#!#&*"'((+'&(&
@r3581
TGGATGAATGCCGCCGCGGACCATTCAAAACTCGCGAAGGCAGAGAN
+
$(&72FH8'#/1&.8)27#06#64@.".A6D@5#70"?H:,>+:C(4
@r3582
TCAGCCGGCCATGCCAGGGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGNCTGATGCAACTGACTCANCACGCGCCGCCAGCACGTCCGNCGGACAGGCTG
+
)D?#G1((*F>7?C*(8&,GA$'=)&B$#H7@#=<@B.)*-##>#.%+B"'/#(9:<?9!"5$E,/$)-(>)<+:H:E7%1D'**>+';%#+B!<?#D)"D
@r3583
ACTCCAATNCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATNTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCNAGCCAGCCATAGCTCTGATATCCAAAT
+
&'$""&'"!')%+(!'&$#%##$"*((&*!#($%(")#*+*$#+*)$%$'()%!$+&$)"""!*$)'#!)+*'$)"&"'$&"!$'#&#(#*&*"%*###)"'"&!#'""&!&*'$)&&%%#)"$!!&)'&'%(%!+"!(#%##""#)#"
@r3584
CTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTANAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGANCGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGNGTTCAGCGCGTAGGCTT
+
5=@+84H0#.E>5>FG;"7F2%8?/!>D4EGD6%54?0'C;6(5F9E%,26?7=#4'886*/&?A,.A.&&?'6AD'@%%7.%%.?:,$0$A.B3H)@6E">';<#0??*8190""$://"9:14F?&>565"-CA;+!2)>.4'$86?@B+5;7=-'-<>!?8(68<HB@0A
@r3585
CATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTAT
+
"(#*/,G/6*1#H;G7,GH)"!-*E#7-".&,1?426-+?.,2#1"EC3)1A)%+B-H?"!8'2A<HD9$G-*G"5$8H)A553E@4.H(,-:D934:>";>C>B
@r3586
ATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTGCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATNTCNTCACAGATNATAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAANCAGAACAAGTCGGCTCCTGTTTAGTTANGAGCGACATTCCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATCCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGNCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGCAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTNGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCNTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAANAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGANCCATGTATATGATCGTTATCTGGGNTGGACTTCTGCTTTTAA
+
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
@r3587
AGGGCTGGAATGTGTAAGAGCGGGATTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAGATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGG
+
33=<@D./0-'4E9@7;,8'C(0CE62B$$7HG2/GG,;,30#)+-//2-+A971"-8,7="A'"6>H"26?##5<3."B/"+-%.C.)"--;2C!%AE-<=4H,8C+F8:E13#210+81$07+$2BA6G,+<(0H.'(-E8.%7AC4!*=@;6+9"10(8#59#>.;>@HA47B'%=,C
@r3588
TCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCT
+
*869"03*.B%<33-9A0D.6D633&/.9B-<327:'#:0@'A*;"
@r3589
TTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCACGCCGAAAGANTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGC
+
7:854"/0)62=#5F6B=/,<9@"A6"0,43<?=DA2G@A//4,&8!2C'E5-4"<5B*&82"F3&&-F4$381,#'E2?/-=/1/:.DGD0F.B'%29/+#:>4F7-05%9(?%
@r3590
NATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAA
+
/68+!6)&.D3-/C,86#"5>":CH1;%=;3+,$B$39?B0.544
@r3591
NNACCCNAAATCTAGTCTGCTGAACCGGCGCGAGGCTGAC
+
!!""!!%"'$*$%$+(+%$!#+&'!*($!$""$)$+#)!*
@r3592
TGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGTACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGC
+
*8"=9@B7@+8*@F<)%05E.2-%)/-0H!@(<<6?G#@)G-#5.5G+?7%!$84%%7AF$)F7?!$&6F$!)/-A:*$G8H7A@9D73C=9D'3;8&7#B74G(E"$=@5:@H/4E./43@9;0<H5;1#G;)%":"A$H2#
@r3593
CCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGANAGAATCACCGATTC
+
)E-+@D8E9.*.!=$!?E?.E9#'=H&E#)>A1=<C)6:!)#58<'B4'.'DH%,
@r3594
GAAACAGCAAAATCAAAANTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCNTATTGCTAAACTGGAA
+
'++&(#++!)'"##*"#(#%+'*&)))+!"+'$!+&!+"%$)+&&"+)%++%%&'#(+"*"!")+$)+$)$)!*!*"!%**#"+(!&
@r3595
GTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCTGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAATGATCNATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAG
+
.HE=A',D)!%;!=9+/&:9'G9%-(-;@33.9>%*)+E&A:?-#46C:C)D<6@<F4.18(G3D#41(C.?.%.7G0:;/1:H8,@H7'<C6,7BAF:0*DA/1<E)%,%$:@;)(#./E'9.G&F9%6<.:G96"?<6;+<G<"*D0BFH56=<+,772,0"E.?H7E!D8'61;-<@018
@r3596
CCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGG
+
>%&1?#:/EA!G"D95E&)7#A6381>B&E3?.'D!>H=%7D79-@6=F#/%2'6'B?4>%&%<1"1;<$&9CGD&183C8A:@<%1+-F%(5#AE1;:;0B6%
@r3597
CTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACANAACCATAGATT
+
BHC,%91!5?,/;3$,A02-H56.5'(8('H'2(-=B,+.162"7F-30&3C"5/#&4+'678C/>&@G<CH,,,D))'C3B0$.-G2@3>$/9A$E5+;,-?=-1GD>C?E%0."8,+HH&ED)(A@?76
@r3598
AATTGAAAACATTCCTAATGTTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCCTCGTATCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGAAAAAATTTAGACTGTGAATTGTTTTATTCTGAACTAAAANGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTATCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTTAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTAGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATA
+
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
@r3599
TATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTNTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCATTGACGGC
+
+54$(<C5<"@A1;:*5AE2F3.#"<&EB%H!G!A@F7;B04"$59DF%%,*-#-7,&?4,?3*H&-4E6D=6.;C$(G+5;*+:'>!
@r3600
NNGTNTGAAAATTGAGGTGACGGGTTNAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTC
+
!&'#$+#%$!%(""+#+#$$(*!%)#$$*&)!*"+"*)$!*#!"*&$)&#*&%$!+)"%&"&$&''!&!)&#!(##(($*('')&(%")%"*&')'#)(#"%"&)'&#"&)""
@r3601
GCAGCGGTCAGTTNGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACAT
+
+)&$*%")%!"*&+)"!!!')!"""%)"'%'%""")($"'!!'!%+%#$!)))**+*$"%"(*%+%(*''"!"++))#(#!(&#)(*)%'!*!!&"++&!"!+##(&"##&*#&%)+#"&#)$&))!$%"&"#$&)*!"'$""(&*!#$#%)'"#(!!$%$$!%%#&*&'$(+
@r3602
TGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTT
+
%25;F(%)GA=13;(!54&$$EE0*!6.$2=DB#!0,*/6E%,<7"7/52@
@r3603
CTNCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTGTTTTGTGCTCATACGTT
+
$*0+;"%<&!@F3/@9?-H;76<?6E/(!=9G/>?!@7&3@DF2%4HG4#??<17%4(.8.@F?+2"A+:B6%D<)-1.G97$;HF*:"!0=,)-#7E.%.7&06'7.@-+0A#*C!")A
@r3604
CAATTTGAACACAAGNTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGNANNACTAAGGCAA
+
+%?F-##09"$6E!&=**.0',&#+E"C1C(4>4DF,)-A:*'"$-+=&C+*%)*&B@"9&!!D2C8
@r3605
CGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCG
+
>!*'37!?5GAD;'-&0<7FE+!A#D)A,.4GHA;+"#*,-5F2;6/%27##,(D7
@r3606
TCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCT
+
G9/DCE%HD5C-EG2!BE"G,B(++5B5CE=C44+@6'>04BD-(E/"@1D
@r3607
CAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCC
+
/-&$E6=->?&:3D3"DA(C(?3)C!06"@C'B21FAA7GF
@r3608
GTGACGGCAACGGCCTTGAACTGAAATGCCAGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGNTTCGAGGCCATAAAGTC
+
E..!2(!:9.1:%$"#<'%0=3-!9!G#H@FH9%'5;,(9*':"6(*D*&>9BC:8H&E1!/,<(3(388HGB%(?GD.#<CC-+.F8
@r3609
GTGNGTGCCGGTGCACATGCGCATACAGNTGGCATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGAATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTA
+
G$#620*,"*2'H!/>8#C>.?(6A%(=2/,*-*!;=)6F$!CED@D:'%H*!-!8>A?G*+"F:FDB%#A;@/9B"3E+37B2$93"%"--G,7%$4?&:HG55,'$4F(;3"+&=#EHBG8=!4;*C*
@r3610
CCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATCACGCAGGCATTATGCTCGCAGAGATAAAACACGCTNGAGGG
+
B1,4E91G<#G8>.2E?6<;.!A.:.6.'4+')DF9A.</,':F#.195-)B9:<;6;939:*?D)*=BA?CF@;"3;G9F&"-F1&@EED#"?-9,<@?;$@H@
@r3611
TAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCC
+
@$BE(?)F''G;*D;7&<6)81;1H5$>D:7:(DF)8!8./$+:H/B=G&,,=49G!D'F#7H76+GB*.//'=+<-,$::%<:B@*1H22/38G(
@r3612
GAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCG
+
B2D>%H(%8;5-7A<7@G=.>!<1')9F#>"B.@@*GD(($E!>@5<G>3F*H5H93@8(D2@#0028$4;3G#%#6,@CGG6*@+-A+=/,/FC@:3B95196(1#!,=G0@"F&G(='6G'?!-.H+G(
@r3613
TGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAGCGACTCACCACG
+
*"CE93:!$G+)1=1-&70<"%('%7?:;5+&:=$G@!+3H,E/0BC:&B;701(1(8=#23(5#1E(%&.D%H90!93.FA5=84"1D#40C;$C#@/$#,(:+,<4*E0)A-F,C#.FC$(@E39(AB.*=A>-CF#G<=4
@r3614
ACCANCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTT
+
%"&)"()+(!#"$'#'")#"$)")#"(+$#"%!+(+)%')+*"#+&!*"('
@r3615
GAGTCTGGTTCAGAAGATAAANCGCTCTAAAGCTCCAGTTGAAGAT
+
+C2F?&+74H%?'09&%A9BE0*(2##A<%<F=G(A/E!>E@!6E3
@r3616
AAGCGTCAGAGGCCGCCACTTCAGCACGANATGCGCTAGCCTCAAAAGAGNCAGCAAAATTATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGNTTCATCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGCTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGNAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCA
+
+G8&HF6?F*?%7B8@1$121#)'2%8-H/;'D7@%"1!D<F?HE3"B$&ED>*845!@#.B8D*#-*>F.:-%7>G4H&('&62G/+%6(C@F>0"*30:0#=/!H1=8882,-D-:+:(/(C-@B17&C.2:!A/?A,>%"E554?<*'#&8:!!=+(#?"G:#$@-)G>4&-+H8%'(B.';1@&&9%9+C=0-F6;7E>'GG)?B:+&H<?:HB8-<31/HB5$*;!%@.(67*85';<?5#$B8*=1;01G$;)5"FH>7*:.56?<19C%57967G4F=74!'>9F
@r3617
CTAGCGGCCGGTGAGAATTCTGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGG
+
&)#%*+%%'+*!#+%+'%""!+('#"+($&)#!))%)*'%!')&(*(!&&!)('"#)$'
@r3618
TCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCG
+
&758E;&(":@)A*G.$BBF#!:.="1C.7<93BD"!''1;*:&6BHC6#0#':EG
@r3619
ATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCNATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTNCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAANGTAAGGCGT
+
-E,""G>%9)+BA@")18D2(0/4F>B2(;35DFAH=<(D3>1#%9F(G=B/.<9E..88-",0<%".'5H:4C;%B.(7#64E2"/@<0/34!4,BB+A*36?<5=(/4/+>',)?2;&C@"(><H)@>%1&25:.<%@4+>BGC#92:<D&2E"';--+/)=0::."#H&*/EB""&"58G-:%H272E,GC3=H2H%H+C:&B+@(!315=3&'F"AG+:C1B7F@E/%)C.52+*C*='87">6)&7'20.H2!*"#<$FH<#,)$9!4ADE=DG:1)26BB2B:!1=*C=$C(610H4B<H>2%@)G#//%>7C?B&1+C@28'H'F(B+G'6&!#A+1!4*--!D$
@r3620
AGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGANCGATTNTTTCACCCTCAGAGAG
+
A"1A52+71G!?;3#=(DF$;5&B$H8:74A2='9)($-$3D17C?#*1@2323*!&>(5B;98&5G*:+-C/0/H$8;9>"(,)>?/"6FHH/!GE>H#$D
@r3621
AAAAAATAAGGCATTCCTACGAGCAGATGGTCGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAANAATGCGATATCGGAAATGTTAAANTTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTNATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTT
+
A@-./'F%".8.3>8AF>?-*?-0'3>8C#8#86?1+2G%8'=@6?,*651&E813!!>7.*+*1:0919(>EF?+0$)BD"B?8-7*,-/#,"++.:?54;)-4"3;'DA%4DE,A%?+3HH<E4+7!G*)??6HE!"<>->0F.(F18"':)3-!DA'#&G:%%423G."&=-DE1#G'.(F-"E+?1-%'0:;;CB"+%4#B4<4,G#1H834HE<>E:<.C6(#4(8>4&!C!@6!C;-%?379*(92F$F'
@r3622
CNNCCTNNNCCTCTANNCTGCNGTNAGTAAGNAANTCNCGAGCGNGAAACACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCTGTATGTGGTTTCCGTCGTCCNGGCCGTGCTGACCNGCCGCTCACTGCCGTCGTCCGCTGTT
+
'#!&!#""!'(&)#*%!#$(*"($!$&#(!%!"*&#'()*%")(!$"**&!+)+&"%%#!*!&"!+'!"&'#%$)(%#"'#'%#$(#'!#)#$$($''#)(%)&+*%"!%%*'*"*+)+(%+$$(%++##)*(+'*%**$*'+++%($!"*)*+(('%#)'!)*&(+$#('&'*(""%*"*"(*"*)&!''''
@r3623
GCAGNGCANAGCCCAGCTCTNTCGGAAGACGTGCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTANAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCC
+
13/G)5B@'C'0AG":>=.D1*1*212:=HB3/1H21>48('E<)7?8+=HD#?/=:!$HAHF<'*07?1ED%.61@#6>-2%7@1-<,-GHE&F044,+BHE@BFAGC23@1C;7>.8(#E.;66)
@r3624
CATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAAC
+
?2F>*@&E$9AD9%?/BFE7!(4'$0*370F>#%F*006:?0,0
@r3625
TGCTGCGCTNGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCNCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCC
+
8##F/@'C$/3B7&%.7+!9/:?.*/.(3(3F7B>.';C>#-3*&)A=.%*+86D%-3G>72FFD8,HG3:5C?:$==<F:4(@*3@>%#BF%7G##4/<-=H,"-A3/E30AE@@<*C9(6&B;>2&-*H.4.#%&-1
@r3626
CTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCANGCCTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGG
+
A-A#8+4)6<+7G:-AF0H4H";%)@84@+/?)F31B059964(=A8F@+3H35A8F-<.!37%;F/F'8C-*@/4;:6-85G6=33;!.4%2;323*A1F:73<1=E:778EC?4(+C
@r3627
TACNNCNTNNTCTNNNCNTANNNAANNACCGCNCNNNANTNNTNNCNATNNCGTANTTGNTATCTTNNANATNCNGTNNTANATCTNATCNANNGCNACNGNTNNNTNNNTNNNNTNNGGTGNATCGNNNNCNNCTNNNGCGAGCTNNGNNNNGNNCACNCANANNGCCTTTTTGTGTTNATACGCATGTNCNNCAANNNGNNNNNNCCTNANNTNGNNCNT
+
"$!$$$"$#"#"!"!!$!"$$#!"$!!$!##!"#!"!$###"$"!!$$$#"#!"!"#$##!$#!$#""$!!#!$"$"""#"!!"$$!$"$!##"#$###!$#!!$"!"#"!""""#!!$$"""#!##"$"#$##"$$$"$!#!$$!#"$"#!"#"##!$#!!$"!#"$$$!$#$$$"#$!"$!!$"#!$"!$##"#""!!$""!!$!"#!"!"!#"""#!"$
@r3628
AAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTANATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTCCCTCCAAACGATACCTGTTAGCAATATTTAAT
+
.*+H,:/,EFH@E'21E)9E>9<F4(F3@!B16H/C8B&<4-7D8EFA!1<%=+2,&?(+27?D11'%;2)>#B(6*8-?:D8064!$%&$+*D;58->8'?*;&=2"+='F'BE=542'$725"%;-9=2:)$D3
@r3629
CGAGTGCGGNTATAGCGGTCCGGCTGTCGCGGATGAATATNACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTNCCTTTCCANTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGANAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCA
+
7($*>G#.114'!B#A-<6D@A&<!D>4:AH/GC903<'7C?10)F4'6>A$B!8G3@520<$!.>6"7?*'A/D/=;&;7#?&H2@7+7#3A-"2;)1:!:*:</HB571=>7$;%)@@(AD'0-++>;:1"">9H52$=<7D;0.-F,&(;)(&3+/.H7G"1C4F(/GB9'7(4/--%B<E2&8/38$!B2*H()%7@))"0@>19,=?H'(+4)H4#(26@6B+#&&<95##07&EC5B@*1H<=.F"@ED*?1'>?4+@5:@=H/G%F480B><C=<%0H@=A96>B-:6H#'+<A:;?%11G!0515'%AGE,-:-:G.F&'8<(DA"GD;!6@;("9/E0*2.83,5+)&/".8!0%7+6.%5-H8C3
@r3630
TGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGNGGTCAGGTGTTTTTACAGCC
+
+%&"*($$'%(#")$'$+!(&"$'##&'*+*#''&#')&()"#)")#%+#)&"$"('$+""!!"""#"#$#+%))"())!'&"%
@r3631
AGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGC
+
>-E(+<&=,>=%'69;;B2<?65'8-"!87)B/&<$C-8.#@<:4>4*$(%7,5C@D?$:)95.?@CA;:
@r3632
TGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATNCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAANT
+
>E&.7%#6!$5++C@D93/%C*A6.F%0%@>-+#9>!C'C"?8%#E4E98".%1.!E<!6-A3$2>42F(=%8#.?;"E!5C;G(*..%A0D9=G&)*+>#G6"2>F!BD(:)C#AFD/7F!FG%32&4(#)=?*:0-64*,9"1"6(HC04.'$D')>&"(A3)BAG)<:CE(B/+=4+3'G#C4D?73!!(4D;53)@BCD#;6
@r3633
CTGCGGTTAGTAGTATATTGTAAAGCTGAGTNTTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTT
+
?6'>%6A0A4E$5>:C;'&1:&74&F%6;*8=-F*>4",G"C<47''%4.9C@!+:F"<$*0#CA&7*"><#5/-($00::G6(?=A7$B/72';AH(CBB4
@r3634
GGNCATGCCGGTGGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGGGACTTTCANCGTGCGGGTGATCA
+
F$7GB?E21*;2#$E(F+F<H"<8?:=0?"3::$1A='DG75*37/*>).5@H-/=H*E9/C774<3/+56D:A74;(@/&:.1"47)*
@r3635
ANNNTGNCTCNTTTTTNGTTTNNGANANACATTNANNNTCANNTNATGNTGTCNGNAGANNNTTTNAN
+
$$""$"!#!!"!""!"#!#"""$#$$#!##$#$""!$!!$$""$$#!#"""$$"!#$!#"$$"#$"$"
@r3636
CATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAAT
+
!/@H),&BEB'=,-12F7E8->E4D:'0)01B17C?'8);.9+>E<74/(&;%;'(,99'3@C;/B0$;>30C/8995%-*8>A-@;E3>@5*;831G(6/$-"G2%2A0!/D5
@r3637
GCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATNTTCTTCCT
+
C12EA(CC".#0HBG6<0765E+'#G81$C728"!>%B3%(D>)@<!%G"A"/8
@r3638
TTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGG
+
*(C@B<:FB0)(6C!B@3#%-G+,61E+01:41'>F(&.2.>2/EH#.;=3,?7D!!B"*$
@r3639
NAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAATCATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTA
+
%B*B+,A1#F*CB)+%+;?AG2G3"40*4::;&?H;<<;='55&;/?;#A$(:*!>)>?9H53.-5A@(;;2A#+'+?./B#<,4=;G1&0(*5&-F--5;;C"GG);&1.6
@r3640
GCAATGTGCGAGAAATGACCGATACCGTGCAAAATTATTATCACGAGTACGGTGGAANCGGTACTTGCCCTCTCTGTAC
+
?36)>;EA:G=.!-6>.D(C!&#6:*0B!F?!(8D2@/E/+'@*<-FFHG:+2166.8CG>+D-C85AA/6B*F=4:B4
@r3641
TNAAAAAACGTCGCCCNGGTGTCATGCTTCTCCAGTGCATCCAGNACGGCTGCACGGAGTTCAGCATGTTTCATCG
+
'+C/C9=507?(.=.A1$(:FB)?>H!>:8;.$:D<B12"@D'$H'&$A411%DH1)3.4+)6G>+'0,8C=6F-G
@r3642
CTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCNACATGGATTTGAATGCCCGCG
+
%A'B:1(#->?'!;7"/5D!7?:5389-''9'+/GE<3401<E78';#(<$<-/%C'05G:.>#$<D4*79A:1E'!,A"578)4;;GF"%&5,7?('27&G
@r3643
CCGACTGCTCCGCACGGGTGCATTCANTCAGTGTTTCCTGCCGGATATCCTGCATCA
+
F)G,(&+62<C5@D?1>(DG38.A/'?"H'F7;95*;4A@9D!3A;F9C&1+$+2+D
@r3644
NTCNCGNATGGCCAGAACCCACTGGCGACGGATTTCGTTNACTTCGTTCTGGTCACGGTTAGCCAG
+
(*&!"%'%!&+$($!*+"*'&'$$"+%("!!&#%!'*'($&&!&+"$""&+%+(''"*'+(+$$("
@r3645
ATTCGAATATAGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGNTCGTAGCAGTCGTTGATGTTCTCCGCTTCGA
+
-0!>971A51;+26@A%)@9=ED!(B90+(*3(=DBB"(@E*B6A#1#$E!'E2'7D25/=4/@=">=8H1=H@!6H>0%8/<HC
@r3646
TCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAAT
+
+'">)8./6=="E/<#4"?9;6C+3E8;(@4A.0A0&>F+
@r3647
CCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATNCGGATGAAGCCGGGC
+
.DH+46B;9,4++%F7$"9B,>3/E<<<%@"!>6A-%&&7>1;EA(/H&<&
@r3648
ATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGGAGAAGGGCAGCATTCAAAGNAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATT
+
70*.0"F4=G$<#)'"3&7*7,;-B64D303B$E%<)FC/!C$FA&3.%:9=&"('A1G;)?$6"D!7#.!C<9A/4;*D%E*B)4-<E+H.$5HB&4+AEC5$G(8;8G1/5.#<>BC/)<F;C*%CH?;;048&
@r3649
TTCAAGACGACNCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGCTGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGANACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGNTNTNTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGCCCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCNACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCNGTGGTCGTCTCTTTCATATA
+
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
@r3650
CAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGT
+
2.8C3FC.,5'+@&",8#!?);&F58.:&#8&<G3%3:8-/F50<2.0>-%8#$9&4'G
@r3651
NATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGG
+
!.+:1;6&.)CG5B;$72'@5HH;:;1!!!@0:$;11=D+,FH+<C!,;C#@585?/H.83=&&FF$D='5@.2620"9-8<%2):.E&HH73;B,FG?H+
@r3652
CTTTGCCGGACAGGAGCNTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACNTGTCAAACGGTGCAATGNAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGGCGGCATGTT
+
--1.A254>@1>/,C!#C<4>"3%GCEC;=%<C;;+51.)9<1C9$43!C-""H'0&-2G8:"-:$%6HF>H(G#CF(=#<D>94A+4.%2)CEEC:7+/E=216FE(C(?0"FG):H"04=<H//>8&-!(CEA9,&/>3A%C<706&!!%1*E"3'G0/<@41/!)$G!@-!1F2?4:)7#.D382DE?A9B+1>(=/G%2?."!9./!7B5?-@4>324:6D$;8%(<G%BG96*E%C5+65)?'%A@/.)'%&98>.C7H2>CDC>,G3C@(
@r3653
CTCNGATGAATNNNCANNTGNTNATAGTNNNNNGTCANTTGATNCCNNCTCACNTNNNNGNNCNNNNNCGCNCTNTTNANNNAANG
+
!"!$""$$$!$##$!!##"$#$#"##$"!""$##"$###$$$!!"#"$!!"$"#$!!"!"!"#$#$"#$#!!"$##!$#$"$""$#
@r3654
TAAAGAGTTTGGATTAGGCANAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCC
+
<G1"%72CE@%4#F+2:':(5<D8@!@&*D=D8<.79/G&D=-.@H&>8!,F/+<032C,+-'@*,6::@(A2=B-:2/5?9$<-1;="GG?:?G+3#&.%'A@F=((2;/H&8!H".D<G979
@r3655
GTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTNAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTGATCATTCAAA
+
?H'("C,E:6'1;#9#=-1>6>5#03ED+!+@B,/@&='/E"!.%(E445=<H+%5@BA7"8$*!+55":A2)76%B5AB'0E#24*3%4!)"D16:4:7*)D36-*6F*((E4=5C*>-3&!6=)
@r3656
CAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCG
+
F:))(6+05%<C,37,:5'CH?E:4;C@)&=$"D5,/48#6(G0+==7/-=86;*)<53$'>F'@5"27#&>G<=&*?,!$8
@r3657
ATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGT
+
=8G,/.)+-2/16/4-0$,8G$?93-?+7GBB(?;158:6.55;=?H+8"/D$+62508-B9D6B3$G('F5C$)#'*+?<A4;(*7BC)=D0B=(1DEG$*?1%%3<)'0<1B5!EG
@r3658
GTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAG
+
@E;H,%%##C8,A1<&+':,?-4C@3F/&*#80B2%("B2)D,1%@$20#D=:-+?2
@r3659
TATGCTGNCCCATCCGCGCAACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGNATAAATGGGCGCTGTATGTCATCGGCCAGTAC
+
2(,;D8-=G07.,<(A-*692:9D+,%?<1*C,=<H5,>#*!-67/,FFBCBH3/,&@?@&EF!%!(=34FEE5(35<(#2F6A9(%C
@r3660
AGGGACTGGATTCCAAAGTTCTCAATGCTGCGTGCTGTTCTTGAATGGGGGGTCNTTGACGACGACATGGCTCGATTGGCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGNCGGACAGGAGCGTAATCTGGCAGATCTCGATGANGGTTACGCCAGACTATCAAATATGCTGCTTGAGNCTTATTCGGGCGCAGATCTGACCAA
+
H692)D)?=*2F#B!><G$E4*=E@,25EEC!@+!/E3,A,-(G#*E4B$8CD?+/C=A)4F-E+0,G:D$7-$4D6($$8#$'(A!C.63=(2(3,@H!:),GB:>*6.@A2&>)G&/9<GH&5E!,3==%B5H0@/1"9(6,,0F!0A"+.D:/D1,2B<$C73,,EB&/7E5$=@&C6:=%#E,?%A)C4<*G:.H<?2,69>F3$B=88-$<?$6<<-'0=?2D3@*-'$)B%$31ACC.H5D=D'-778#)H30:?!!&H;@027C#33#E?:,+6A-=B*3D=*<#,99>.0595.3F?GF:B=/9F&-?BB5<9-<(""%+F),*:4
@r3661
CAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTG
+
)BC)A*1$&+4/$AG5G:;9A%!>7"6F&H>5!C2%B,E-D48.C$"'2>9H.2"AG16,3#0C'3BH8(;,>)>/FC/!DB-3:"'8C:+%74+7;!=<9>GH9%:E9573H/!?@>($/FEG>/1<A'.+@1!)*?@E.=B&+!94-3"=3F,'?>';*0H(?44%'>C4:*"G:B
@r3662
TGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGNCTGCATGCAGGATGCGGACGCACNGCGCGAAGG
+
*6#9B,!==%@)-3"7>05(4@:95,"AECA-(.+6/?+C5'(#*$!=H-0$F?=2'3(%B.*=#19-55
@r3663
GGAAGCAGAACCGGATCACCAAATGCGTACAGNCGTCATCGCCGCCCAGCNACAGCACAACCCAAACTGAGCC
+
<,EBBD-/F&"*(@!$D(?G?4"=H>48-C?83CB#>-/%#B'B/!8:>!)52549:?@>8:;C=<0B>B$7.
@r3664
CCTCNCTTCTGCTATTTCGCAGGTCTTNGAGTTTCTGTTGGTACTCTGCCTCGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGNGGTTATGGTTTGATTCGATTTCGTCTACT
+
))#(+"*+'&$))))''#%$+!($#%($*$(&!#)"")&+$#%$*#$%&+$&"(#(!%'*)++)"*")(+!*$''(((!'&#%)(*&%)**'$(#%#(%"!%'*$((&+(%#("+#
@r3665
TATGTTATGTTCNGAGGGGAGTGAAAATTCCCCTAATTCGA
+
(BCD0!-7290,,2?A%<:;H.CGH,C8(H.D;2129%;@)
@r3666
ACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATG
+
::8E.1:8='(4A($C-2+?-EC!$1!>$%"F%.?""!?4";2$/9<?'/H;
@r3667
AGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATNTGTTGCAACGAACAGGT
+
3*%.8;:=4(D/@81-21!;H=BA9;#.+E8E!96*FEC0"+9FE-4D108/D8)C-0B(8=*.!GH2645E6C*.&:!%($&4B8:9@-)+!8,@@"C'@D8;#F"E*>.;&)B-B+3#G)-H<?'<1:9DB5D3GG@"B'
@r3668
CGAAGNATGTNNNNGTTTTCGNCCGNAANTNNAGNNTCTATTNGTGNGNTNGNGNTTANCTNCNNNGACTNACNNGCTTTCCNNNTNNTNNNTNCANTTNANNGNTNTNAANANACGNGANCNGTGANTTTTTNNNNGGANNNNNNNGCTNNCAGNCGNTAGCNNNCNCNGGCNNACNNAGAGGNTCAGNACATNNANANNGTGNNGTNTACGNATGTNCTGATNANGNANCANGANANGNNNCNNTNNNGCCCNTTANNNNTTNGGNTGTCTGNNNNNNNNNGCNGTNNTNNGCNCNNNCNNNNACNTNCANNCAGCNGCGNTNANGNNNNNANCNGTNTNTGCATACNNGNNTCTCTTATNTTNNNCTTCCNCTCTTANCNTNGNANGGNCNTCAGACGNNGGAANGCTNNNNGANTNGANANANTGNCNANNNNNNNNTNCTCGANGTTNANNTANTNGNGNCTC
+
#!###!$$$$$!"#$#!"!$"!#$$$#"!#"!$$#"$""###"!##"#"$!$#!"$""!!"#$"!$!"$$#$"!$"#"#!$$"$!"#$$""!$!$""#!##!#!!""#$"#!$#"#!#!"!$$""$!""##!""!!!$$""#!$!!""!$#!#!$!#!""##!#"##""$!$"!""""!#"!$##"$$$!""$#!#$$!!!$##!$"!$$#!#!$"$"""!$#"##!$#""""$$""$""$"!!$!""#$"#"$!$#"#!##"##$"!"#$$$$"#!""#!$"$#!##"!"$"!$"!"$#"#!!#$###$"$##"$"$$"$"#"$$!"!!"!#$"$!"##""#"!"$"$#"#"!!##!#!##"#"#!!"##$$"#$!$!$$"#$!$!#!$""$""##"#""!"##""!$$!!$$""#!"""#"$"$"$#!"!#!"!"$"##"$"""#!#!$#$$""##"""#$"##$"
@r3669
CANGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGTATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGA
+
B4?>"C:72E$CDD%F#F&,8)B""",A"5'!7?B@8*6G2/H2!45--E9",+"5+H></#E1GB?7,&9/%6D#?/5"<.D2A;9>"&:)3(=@;2(7<:
@r3670
GAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCA
+
69.(A57(*<AH#61?@&."3&D1@,!4F@&'-:+B=E$FF#53G$7EEEE*4,9?#D44&&@7'*/AF?:C,.-D4$09-E7%5'%,<B
@r3671
ATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGNGGCCACNAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCNGAAACGAACGCATCATCAAGTGCCGGTCGTGC
+
*.#+9#03,)2@HGH=1A4*1.E5,&<@=*4"$G$D!3!<-/;*,8)(;!+*7?B",)/:CA)C>>3+"@0!67-%C;>@H>F!F2E):D<6(2=("$/G!BF68F"A3--*><B8E418;D>(E0#B,CA-6E>.*$HD3,<"C;<C<#6
@r3672
AAACAATGGAAGTCAANAAAAAGCAGCTGGCTGACATTTTCGG
+
*70:%/0EC3.0'!/<>7=9$&((0!H,/F*9-6,B&'6,6A%
@r3673
TTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCT
+
=+5!A%*@H(>;)@FFB#/:'H:)=#!:0C#;>:+B@E%E::HGEB:)@84DB$'&06$+#",H3-.
@r3674
AATTCNGTAAAAAAAGCCGCANAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCC
+
+9F9++&2G)?41=@<4H5F?)0)?(D67.&+#34D?!99!D!E"1C#9/,7"C/,E:@4G+?(',E9
@r3675
ATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTAATAACTTTTACGAAAGAGTTTCTTTGAGTAAT
+
3'27E6&$*AH<FD-D1B*;;@5&7:D'"=@>)<'59/"GC90/$2#?#62G2:G/DB@7G+D:D=FB'/>(3,?*@?'445)
@r3676
ATCTTGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAAC
+
%"$!"+#)%*+%"!'(!)$$'+$)$%!#*'")%"$"'*'%)(&%)!'***"'+"$+$%')*"!"%((#)+&(')*#*%!%)'&)
@r3677
TCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTNTTATGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGG
+
70*D$>=?"GC63=7)8@"+=7@*;B?E&(%BHD9HG#$/5+&(==D9G(:'!E0>D:!%C"<,+&:'#7>A<F(>;(G/<C/92$5E%-$G88&E!@.7FF=724-CAB5/-%&-7"(AG1B#,2?8*B<GHG#8(%D/6$-;E#2;%65&/=&<6"%(CEA(?;3&+'%FE
@r3678
TCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGNCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCNCGGCGGA
+
G7,.F";A*A.!*D,;G;>/C4G;>@6F/F/F!4H$.0D+33(,C&/5:8(#(;D?6772D;,5)948*C1(!;??GF(*:.DG$"G?'D>63&*BA8?H>#D*()?>3'07!?,=C%=B562D&,&$@'5>-E$=%&%/?B"56E5?<:=9GAE5;0!@16.==4"F1=EH3$?)!G
@r3679
CCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGAT
+
0E*3(F;8,1,F#F>:-4)%@76"B0-B$)(@7<;+B2(2EBBG>(,895;>5<:-6?&E@'$>3*4<,=A#4CGC61%<A2<,+$?5%+,F0@1H>D@B155'>9<>?<%4E>
@r3680
GCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTCACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACGAAACCCACAGTA
+
4.F9%GD)3@.DFE7#0D(".$CD8++7$1G;&FG7+>5F>!;$!?>9+9:638,-BH$:%1,>B(,&>(-%1(=?*0;D"61*;('?38%<@/G1B>%521D;&!=8.%?-H
@r3681
GNCCTCGGTGGTGATGGGTAANCTGCCGCCGCGCCCGTTTAATATCCGGNTGCGCNGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATAC
+
$&+"(+#'""$)**%))%!'##*&&$($)$!#$'(&&($'(%#&'#!)%#+!)(&(')$+!(!!!*'+!#"'+"&+&'%&%'("(*$''&)')#*$"**+!+$%(*))")!'%*+
@r3682
GAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTNTCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAAC
+
84#3;=FH/.%5<"99'3$:$&F=C&$DFC<D(-AA0"+?<$FA9:'5H,H(%<@03F3:%HH4B:/9"<-9=E%<+;(#>%=%CG"$E:+@0?2:EB7.42,H$'B/=)/'DA.("
@r3683
TNNAGTGATTNGANAGCGGAAAGAGCATTATTCAGCGCCCGTTCCNGACCGNGTGGCTTACCTGCCGGTATCGACTCCC
+
&"%$)*"**#!$#"+''!"*"(%%%$++$$%%*#"#!($'+&)'"$!*'%%#!&&(($$$%&(+!(%'%"$&***$((&
@r3684
TNCTNNAANCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATNGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTG
+
)#$%*!&!(+#!$''$)*(&)&$%+"#(')!%!'()%($#'++#%)"'"%)+*'#%')$%#$()++$%'%()*%!+*$%"#&%%')#+&+#&")+*&"(*)#+'*%(*!+(')*!$$*+'"!))%)((+*
@r3685
GGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTG
+
8%54A0.8@C;H6G*#;-?=E:"("DAG?2:#)/.,#,(;>#(!5B66#G##.3435-$/3A=-A*4#,H:"&$/;H&58:?E@C(%:#9A*1'32,%E?+6)",F=)=H23=9"F"D&AGD,$9/E7(:5%,D=7C&A/5!+)B@C62!8
@r3686
ATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGT
+
#%:A0!A#B-@,!1C?+/3;41>7@:)(""&!$GA,H,7H@',#$$B,5'$+A!987-0</?8>8867/B;3C6;
@r3687
NCGGCAACACAGGATCTCTCTTTTAAGTTAGTCTCTATTACATACG
+
#DH#5;5:7$'B:'>?.$D/=D<7'0;'1A@;H5((C<HBCA1,F@
@r3688
AAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATAACTAAAACAC
+
GE@:BB366526'&#(E+?$"H?479'B/<';",30D;=/$)4C"%BGEG><27)'":B!
@r3689
TAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCACTTTCCCTACTGTTAGCGCAATATCCTCTTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAG
+
68()-670(8@F*.H>&$-!#.#-20;!%EFB'F/5?1$$CG180(>A/*GC$,-*#H''0@*<9E01E=E-19$B?-:C)@-'(-1/4$:$C+<.3+5>,>G#.?HD38-&-H&59F1E669?9;GBBG!"/4=;%<=-#:@G)FF$!BG#,0!(-2+BFE!==(?E7!H=(6*G#23
@r3690
AGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGNAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCGTCAAACTGTAGGGGTTGTAATAGTTTATCCGA
+
?;.H;1,CB7A6>G>;5+)(0;@F2;)G'.0+335!->G./8)A*;'%/C5EA#1+&+B+CD+/"'>@;G3>G?8%5@!8'(EG*=':@#?71G%5086*2G)0&'8%B;,%+'5?:<"5F(.,<7F.92:G>?;11<'C;77!3F.=C=6.CECE>?$#5D+C6!"!C#9*93#<?F92&23F+D)>;*D&A<,$%?#>#E/.-6H6EH&F2)B/?".7A(B<HA$<A77-(BD'#<5?E=<6G.%08,)GA(:3
@r3691
NNACGGGGANCAGTNNNGTNANGCTGCTGCTGGCGGATGACGCAGGCATTATGCTCGCTGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCTCTTTGTCGCCAAATTT
+
"$)#$$&$)'(*&#%&''(!#!()*)+$""*'(!#$)#++$++()#!&&'&(%&%#!*#*'#"&')+&'"#+)#"%'")$)$+%!"#("&&)*!%%!##)*)(%$'$%#%)'!!*$*"'&!&"$(##+$!#
@r3692
GNATTCAGNGCGTCAGGTGACGCGTCGATAGCATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGNTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGNGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCT
+
()$$&+"**#)"$()%%$*"#"'$(+"++(*#)#*#("$'*(%"')*)+$+$&"$'%+*#*&#"((+&"$("(*)%+$(*%&!"*#!)&+%(+$)+#'&#$*'#$+'#!(!+**%)")!!)+!))()&&$!&"''#%')"'*'(&+%!&&(%(*#))#(&(!$)(#&')'&(&$%((+#)'+!"(#!#!!*!+')"*!$)(#&*!"")"####(#!)"$$#')+!!*!#
@r3693
CGAATGTCGCGGCGAAATATCTGGGAACNGAGCGGCAATNAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGNTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGAC
+
D8,&"<;&/G.9GB93:#34:EE!-%6FD71#DBD7(<&<5FCC',8<+H'6,1+-)7D)+E9.6G4B*5G+)>/?'*@',BCH-<1/-FG<GD?E&AB5G6&H6*8+/2D-/1&)B&91?D*F;%>>6B/)?>B#@!G(,@</B4-08.7A9<B&39@7H?"G
@r3694
ATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCANACTGGAGGGCAAAGAAGATTTCCAAT
+
7-)"5;F:?C"('C9F=!.'8'C@$$3F&3?6E831?74!1A+E;=H!#/F0G9;=HB+%#F=*F':4+<5GBG@*AG"2!!C218",'(+H2@0ED4"*(5-,/66(
@r3695
NTGTCCNCNACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGG
+
",5E=0<$986=>D(D;2>B%,<=(5663D5;.6C$$@2,+B#9GC-05/F,71@:220.-F.*1E74B)
@r3696
CAGTACTGGCCGATGACCTACAGCGCCCATTTATCCACATCCGCCGCACCAAGNCGTTTCCCCATGCCGTAGCGCGGATGGGTCANCA
+
+"#&&&!$'+"%!%#"%'$"")+$*+())"')&$$)'&*$)*"#$+$!%''&!&&$)%!!#$$#+"*%%$'(+&))'$&(#&(#%$%(
@r3697
NGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGT
+
&)8+=%9#=GBA=G353/=A8%A#C78=$#,2@":<AH1*GE)/H4GC.*7-(B!-:
@r3698
GAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAA
+
8)@+$8+H$2AF,-217GF==;=HH=@B3=B334;5$#):B&#HG9C1:%EC,D,F=*G73/92F),A
@r3699
AGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGGCGGGAAA
+
)69<+EDC)@/8*373?3B#@<!4BH96<0;;1<1.(,7,?0D:9H.<777H(>)@,4@-@7)$/
@r3700
TTACNNCAGTGTATGACGACCAGAGCGTTTTGTTCTNCAGCTGGTCTGTGGTGCTGTCCTGCGTCATCCTGCGCATAAGGATATTAAACGGGCGCG
+
""*"%'%+"'&'%#+#&'")+'&(!""#&"##*#)*&(+($!")'+(''%(%'&'#)*+$&%%'("$+"$#)((')%%(&*#+++%$)*)'+!$"#
@r3701
NNNGANGANNTNTGTNTNAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGAT
+
!!&$#&$"(&*"%#($%*+'""'#$$$#)&#$"+!#+&%%+"%"(#*"+)$%&&(!'#**+%(#$'
@r3702
AATATGCCGGTTATCTCGGCGGTGGCAGCGGATTTGGAGGGNAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGNTGCCCAACTNTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACG
+
C1$.E(-@>(/)%EED0#7$C)(H/>A!/>>@BG(*3,=(%**/!B;)#E+4CH$)F>:GF=<(&3">%/$&-9!%,*;3EAD<+9A%$G#G>440.:%91'&<57$/>"(>,%567%@"%&$C@3-$D>?;0-.7B?5'G6")D),0G17DEB!B-03
@r3703
GAGTTAGTTGACTATACAGCCAAGCTTGCNGAAACGACTTTTTTAAAGGA
+
F3-H#5+&&35D1366=.A=8>=(=A7$#D15:.B/G%/8B,88,F+8C"
@r3704
ANAGCAATCTATGGTTTTGTGCGCAGCCCTTTATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAATGAAAAGCATATATTATTNCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAA
+
*!(#++&!#(&*'!&#*)$(')#&!(**)#%#%)&%*!!+*!%"!"*++'+*$*(+!#&&%"&*#&"(!&#$""%+$$!+$*$%$*&)"*)$&#!)&+*($&%%##$+($"!+"&)""()!&%&'"&'+$+"#)''*%+&*&!'""*&*&%((+*%'(+#'!#)'**)"'+%***!+#+%$((!'!"%$((%&%&!')$'+&'(%(+&$(*(&(#'%""("*#"'*%#%+)%"'*&'(*$+()
@r3705
ATACCGCAATCCACTATTTNAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTT
+
$20),8@5%'5):&5;7(%DE89FGA4;%(-><$!&;G<*>09C?,141*(%"95";@*B?A?,;5B2&?@-G/->(%=G%*?%<6870$?*A2<C-"/7?7"5@8(346F(A09E/%H=-21B0%?+$$C3D>??"":.::8$.C+82,-A1368&D1?1-$B==!4H?(>3;:(674%=(::<=H5)*6'5<0?.,-*
@r3706
ATCCTGCGCATCCGGATATTAAACGGGCGCGGNGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGTGGTG
+
&G&+">:(*0#H>%$+H(%FD*F7/2&&G,--0H96+H'4G?>?3>B!47/77ECE=C/'%';!D*9G2:'*9F5
@r3707
TGGGATCCCTAGCATCGTCACAGCGNGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTNGCATCTTCCGCACNCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGNACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGAGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCC
+
:,(.1''5B,1$3@D4/1/$$B)B/5@=56=%;A(-,H/8;#2."&5<#9.'C'=-'++D?A)/7)0E+7.BGC17F88!>$5%H4,9"4".*=FG95?:@/E4?G>*3?EFE1G95&#",1H-FF,=0G''.D?'A+685-/#$0-/.9,)6B/1,6&F!9+237:&?AB"%/*7"+65"F*/A7)<.>9/:(.542E',C.>1%+?0!<07B@,!F91EH7&*@F2%210B2+FG(C4<?>3E(4FG#2AH%;E,8*
@r3708
NANNCNGNCAGCANCGACNCGCTTTNTGGAAGGNNGNGAGTCAGTTCGCGGTACTGGAGNAGGCGGCGCAACGTCGCCAGCTGTCTG
+
#*!!)!#"%%)'%*!&!'!&'!&')#&%'%''&!((!*+%((+#!&!&"!!)"%!&!+*($%!!)#)$+*#!$"$!++$%+%#%!#"
@r3709
ATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGNTTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACNCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTT
+
0(>/4&7*B1)DE70/96H!G3F>@-,.:4"/:>B(E=.235A(/H"9>'/!"D<35<D5/6ABG1=+%)"3#78@@%9/,7%HC+G/F$>)C+/-DC-*?B/?/:72/B&H"*-8?.(+H&'C#5(1>H1)3!.,/G-'37@!6$
@r3710
ATATTTNTCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAA
+
D=,<&CE4?9C(1D=;%D4+7)/?01D!$.(99##.<36&H083
@r3711
TGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGT
+
>1G)B-,6B:4?3#+6BE;-F38%#@F#0'6EE@!H%6@>4-D$
@r3712
TCGCGCTTNGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCGCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCAC
+
.D1;H-7=F/+.HB2@'$8H+#=;)90'7(3:.=$*>:$-29)B89*=8@B)?A&!'3:A7?7%E"=BF+C+*H(#)8G<%#-*CG2F0G?5#;1B+"+0)E'7+:!A0'3D:$F%.%+489>?'2G8@8=*.<B1)F/C,@.4*4A+!-#$:4AAE5$>>A3?@A/%-A+&C;GFE/C01<2-$*&HB!H3(*'-4H@3=*BB$#-6C,>&A@<6,6$!/08.G%"!=-<'9&(=/
@r3713
CNANTAGGNNGNGGCTNACTTNNTGGCAGGCATAACGGGAAGCCACGGAACAGCGCCTG
+
%&'!)(&'"!&"%#$'$'*%!"#!*+&)*%(*+!#!##"!'$)!$))&&'!+!("!%)+
@r3714
TGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATGCATTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTA
+
D92BF-)12)>2/A!&>89A?H5"*8-((H;:"5.?D%"CE1(H7(D@@<.&B''86/%,;&.&0*?E'#$128@54>F7C:)83FD:)3/H)?<H/@40@&8#(634<(&.&/%&4!D=D3&A%<6=4/@,E0H01@,@";E'&#F,#2,E6%6FFC+.+5?<1<E/.!!F086$$=D"46.*@<<%
@r3715
TGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAAACTATCGCACCATCAGCCAGAAAACC
+
8B"2<"B';:2.D=<>,%8G9B&E1H@<);G52%.1#;(H31F470=%*)1@4>F)='?G26?!H<40@F,A)(-537B<
@r3716
TTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCAT
+
1,A<=,0,F?"@:H,$"A>383608/9GA)(+5.%%??!2(9B7$44",#1E=;2=8E358%"F'7:C/@,7(-/2
@r3717
TTCACGCTGGCGTGGATGCCCGNAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGGTGGGTCAGCAGTATCGGT
+
:8E?11E,D!G,BG&0688#5:(#31@(@$/(@:C'2560A2"(;/-1?0D:1+7=9?6=F!A19@15":G:H-%(7<=-7?0!$4G9D6;>D;586&<;1!#CD8,6)&#+"<A!-4'+9FB>$&...,?A37$=-8B>?
@r3718
AATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGNTCCCGTGNCGGCTCCACCTCTGAATTTACGCCGGGATATGTCA
+
%3(BD14-HDHB)11/B13%:?(6E13/7+*<>.<875,70.>D--?15$>&H2A877"2E9A*62:2>-#=77'00,%5!.:9=8BF,1''7036=9D,'G2(*0#
@r3719
TTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCNGGCGATGTGCGCCAGCGGAGTCG
+
GCA%$F$3$#::;07)EH)$()//4,,4G.>('C;<$),92.G>&$C?C*",=9F-9%C".%4$A5"$/<H9+-7>C=
@r3720
GTGGTGCTCTCCNGAGTGTGGAACCAAGATAGCACTCGAA
+
G7,DH&#A689C/!11BAA.#:.A$A5F;<:.9=(211(9
@r3721
TTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACC
+
6('21A+B*'"89.4#88-07C-9H).9G./CF9F>#5?9E*BH+GD&=C;+6,87?9;(F9.;4141
@r3722
CACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCGCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCTCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGT
+
4)1F-ABG(494<-,>5%!+D:#:B@D83H4#*5DHB<37E9#!:G/F)''7@-:9.AFF1B2-/C''9FF)'0#D'H1!>>=%5>,-H7F*26*12<?@9%D78(83(.;6'7'AH6&905:,?#A@@E"#4':A5H)++GH*".2CH-)*'9,/./-=C?*<;@%:4""D<F&;*0@C&<($8);63A0:9BB+/C1>F<@1@1!DHEC"(?)E32@8B-936&D>*9()/H/-HA4FG
@r3723
GGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGNCGGCAACTT
+
)+&+$"$")&*&)+%&+#&)#*!'!%##$+'!)"#!!(*'*)&#)"*")#!"(+!"&&(*##"*)&$)#!#)'"!"!$(++)+))%$*'+''%(&+*&'$#(
@r3724
CCGGANGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATNCGATGGTGGACGGCATTCTGCTCGATATNGACACGCCCGGCGG
+
05*.'0,)7$G3>BG:0"31C>13.<*GC2'3#(74:<E-%HB*<G4(-!><<#0#/-3+87?54&C&:%D'*$:-3>8%,"6%'1A<$DG'#607:',C719+?71?+)0),5"4H&!-*1&8E#
@r3725
TATAGCCTGGTGGTTCAGNCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTT
+
)('+'%))(&!"!!%'(($"!#""*"*"((!*$')(&'+&**%(!($&(''$$+("
@r3726
TAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGGAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTNAACGAACAGTTCACCG
+
0&:F&B<95?.78.B@.?=4;+"9?,&->"!+-8%2;8B;!:$C6)G!#/50-!B2%699@+=<G;'=6C(@BH,?@:/-1;;72)5F).;!(:5(7A,*$=1=F2C2E=?C"E<="/-AA<D?6')HD.8"67/561@(5E@19(G1?GH%8%6124'7("F%.DD0F*A
@r3727
NNCCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATANGGGCCGCAGTGAGGAGAATAACATCACGCAGTCC
+
'"#2&;0+-4GB=E.0D,B:H2*>G@!1,:E10+&+.E8>0C/)G,%D#G-.<&#50(!3<88/,#>#(BE/?(+2
@r3728
GCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGC
+
9A:>H*@%3A50!%";)HA2C%7:@-EF@?F4(/E$);C&085@:%-F1H5'@=EED%C:+/F2'>"*8??A,-BBB<5&)3!/F-@<F%G%%B)GE"*%)%AG$9!'2,;+%@0B
@r3729
TAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACNATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTT
+
G/@GC,!7H#H795+G6!3H5177B=.-<'4/.;G#,3F&<$,-!&:=+'"72;*F&9B/%$(?>#9)+@(76>D780#5!F9:FHH287G568>96-4<2&H
@r3730
GCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTT
+
D?(1F8&G"&2C->GD.BD%>:/*7A9<54=,<25=A$+2$(?5E"+>.+D2:;0844E$7@:5<=B36!5)-D$2D7=37;1!'='@F1?;8
@r3731
TGGACATGGTACGTTTACGGTGGGGTATTTTCANGTGAAACCGGGTACATTGCCGTCGTT
+
2@)=?)65$C11&</9;<1/#"3A>D6@8,.2.8(D3(4.EB*%)6E"@2?877#66E#9
@r3732
TNNCNNTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGNCGCCACCAACAGCCCCGCCAATGGCCCTGCCGGTACTCCCGACAATCCCCAGCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGNACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCNTCGCCGCCATATTCTGTGCAATACCATNAAAGGTCTGCGTGG
+
)!!#&!+$#!&)+$+#)(%+(#(#!+)!#(!(%""&(%+#*")(%$($%$""!'#'!$"#&#%)$%($')+&#+!!+%+&'&#%'+'$&$+%&"'(*(&!(#(''#*+"&$%)$##)'""'+'%*"!#("())*&$''&"$)+("#$&&(&%(((*$)+%&*$*)&$$+)"!%'#!'+'""($)*+)%%+$%&#($!)$#&')!*)&+*"*+$#)"(*(($!#""%%#'%(+
@r3733
GACGAAGAGCCTGAAGATGATGTGNTGATGCAGAAAGCGGCAGGGC
+
F;,-C:GC6DA:A=C<E58>*"4"?<C$++04G9'H*+4C,EE-(B
@r3734
TCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTNGAGCNCNTCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTNATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGNGGGAGTGTCCGTGAATAATTAAAANGATGCACNCAGGGTTTAGCGCGTACACGTANTGCATTATGCCAAC
+
5H.:?+;16<F61/6)!FD;,$3/HA++02/?G$3=7G8?<3?'D>#2)4C<,)8(D-D;78:C$?5')%==8$?5.;5+4<G:>*7>7E$0367B=80;A-%><;-;*=$10@=40F)'E+"'9<77@/"3:'3D>C+,)5E5-/D3*?0D2470./0E)*FB+F&?"8$C'',&>!%>-5@64=8%0=#3G'#@)$8C)$0'0(E=4D14(19+;=$@+27!.>:D3,E6#86;42>:"@,-=<*H1C.*#8A&8+/&92,-G.=B(?;18=!$<3A,,(C0*43/04*+"AF=3)C$$5!F')1*:)5H?C=26<G+E+F<19!2'A,2#@E>8-C,*3%/@?*7%D23?!#)00B($GG&G5'49E@".'%/71-!<%=-+)7.?DH?%A9@<-).9#)
@r3735
NNTTGTCCAAGCNNGCAGTTTCANCCGTGTCATCAAGCTCCTATTTCAGCTCTGNCACACGGAGCGCCAGTNCTTCTTTCGTCCCCGTCAGGTTGACATCACGGTTCAGNTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTT
+
&#'#'(%*!!!%"*+*&"%#*$*'%&$)(%(%)!%#)!)!(+)%&'!(#$#)#&()**'!%"(&("+$+'()**%)$#!'$$#&*%#%&#**#"!+#'$'"&"+""!**)!*)$%!'(!!"&'*(!#!$$+%#(%+"(#'#"""$%+"+$&
@r3736
TGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCA
+
8HFA=5+.>D=(5D:7>%#"--<:)"1!5/";==3B50)=6
@r3737
ATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATGA
+
-GCC?(<#$;3+FH)/0A,9#7'%9)<%>.%=):A7%>93B:&#76.3$,?</7!)9@#71)>*!?,&<BC?/:9+#8%6)BB+A"F%066$#.5G<G#.5<9$6>F!3!F0E4"<*7E<8$7"*=E!0*A9$C2$;,0,&6G(",=1,(<3
@r3738
GTCAACCTTCTATGTGGTTTCCACCAGTGCCTGTACACNGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGA
+
*&)*$(%%#""!""'+'$%'&*$(+)$&')+')'&')+"'$)!*(&%%(*(#)%(*"'!)*%$)%'"$$$'+&)%%(%#%(&*&)!$&*)*$'+"+*)$+$+"!()+"*%'*#$!()&+$%%)"$+)'&'(*+!(!#*
@r3739
GACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGT
+
B5CC*8*%$F/9.%0>?>)>6C%CH(4?F=*=0/2(B=E@H-@)G%-4772&4@,446
@r3740
AGACCAGCTTCGCGGGAACTGGATAGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAGCGCCACGGACAGTA
+
28+C""C?C';(.H#@*2?''/%(F/)7"%18$B3>+7E-6)'<67<?7(8*<@B*;96+980BD#2)F#46&5B;2
@r3741
NANATCNNNNANCANAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAA
+
'$!)&(!!'"'"*!!*(%+)+%!!*&%**+)+""&!(#)%!+(#*'*!+)&#%&#')%")*#!*+*'*#$)'&$!%!$)()*!%)++'!%(#"'"'
@r3742
ANNTNNAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGNGTAG
+
"&!$%"('()+$!%#'()++$'!%*'%''''$!(###&'$)#+%#*#&$''!*('%+))")"#%)!%")%+%&("*&#+(%)'&'&+*&#*!$')#*#*%(+
@r3743
AACGTATTCGATGTGTTATCTCAAAGTGCTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGAC
+
+%#&#+'$!%+&(*%'")+*$$&)%&$'%'"&'!+"+&&*(!"%!!)&+!&&"!((!"**+"$+)%!%($'"%&(('"#'"#!!&%$#&$%*#*"+($$&!%"%%**(*$(%"$)'&'%+"!'*(##%)$#*
@r3744
GGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGT
+
7$"4C/@CG&4'!*G')E&(:7:0A@5,+1F#.!)E&',2C'6032#?04(1H%<2782,9;);?6/+D<->A)9+B,D;H)C:=48C)":4)A!.&17?@E!;(G-8F5F:/(+#+8F!.>/*G2$67-2=17:(=C.
@r3745
GGCGNAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAAAGAAAGAGGCAGAACTGGCAGACGACATGG
+
&')(+!%+"$&#*)*!"!%("%)!+'%$"*!+$!%")&"+&*)"!++*'++#*!+&)'(+$!##&%"'$("$(&
@r3746
TTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTG
+
35/17=*A,:<72;!,5:D-A4%8277")*@"0$'C<9A=."-=<A5
@r3747
AAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTNCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTNCGCCGCCGCCATCAGCGTG
+
!+3&67"H4=D>",4(!!,8):&G:!'F/:/F2C;@:)D28&!6+$,F9@$.,-FD-!%)D>!7'E'-=4+HD'80$;4!"5$G,H9F'1/</4&E8/&45""!
@r3748
AGACACGAAACGCCGTTCCCGGCAGCACNAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTG
+
E/G#!*0!0%.-@=%/H#D?0!D8A?9-5!-'/>';*%*%-"E:,@*8!?+9+@H6?H?2*%>%H/<,*5?<+(8)1!F).5$C(*/
@r3749
TGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTG
+
=!BD30!E3@0947%<=$=//DF*'*!*B'6A;B#0D,?4,34)="
@r3750
ATAGAAAATTACGACGCTTATCGGAAGTGAANGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTNCTAACNAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCA
+
+&9/FD2E!<8D+C;AD*/<A;=+(C5"B?8E?#!*+%<&#5$0HFB/23/:&647$""+0+G=9;E',9;8B1H>F%*2&H+4F<&'F"A>4:+<C&D:&F4!&&C48B;HG9>4C39E4;9D4>
@r3751
NGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAAT
+
$>F6'.-B:F>9F8ABA?F&+-8FD>&H$2<(8(!>H-404D:*
@r3752
GCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGTGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTATTGAGCTTGGA
+
=8H',@G3*A)/6)=-G)+=+77$#2!3C=>."2%;;:432#/$8)5,447E&G;!E"5%<0=62"059'57?#51/5A@93H9!A#(4A.$)+29AG1(3!D,D)F;:6*:DF
@r3753
CTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCATTGAGATCCAGC
+
/GG8:H;*;D+>E;B"?>H2<).%<5$&./5.69%-7+$G;8B)DB$'#(/302"@->A13H(F)5.H=#<<$#7:"1FG*:H%$->,/D=@A/;"$7D3FB/)F3<<!;5DF@&@E,%-)7$()13$$#DC3#<66274"FA!B"1C4@*%1#1<7""@C<F
@r3754
GGGGTCANTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTGTTTGCTCGTCATAAACATCCCTTACACTGNTATGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCNG
+
'2-:);3=("0FA+!6EA"//!!5FHC%8B4:&*;D3'7>CH70)A,8>959B(F7+!.#9-;>2G9:)1?15E>+78E&.;)!+5'16FA:815*?#=FF/>6?D3F(B$-H=G#"8B:,97-.4F<).!2G6*8F-F0$+"%8>C:5&?E<HF4,"4H7;>)*!;F0(G10>G+E*G?E43+B=<#*@10;2,66BEFAE8+9$.,%>6$E1E=0B9F"=+5+>=*9"E34
@r3755
ANGTATTTGCAAATCGAATGGTTGTTGCTTCCACCTTGCGAGGATATCTTCCTTCTCAAAGTCTGACAGNTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTC
+
##+#*'"*%!%$++%#$+#+$(**'''(&"+*&%&$(#"()%#+%*"&+!$+&%!'!*)$&+'#('&(+&$!!'++!$*($#*!*#&("!+($*')#%%+"(++(+!!&&+&
@r3756
GGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTC
+
022A.7,F'/-,*/8H;G>B1B*<BF&GC!(<=+"/60>88?>*(>C/;(;A'</!!9!6?+5'=*4"":0$1',3'<?5-E#
@r3757
GCTCGGTGGTTCTCGTGTNCCCCTACAGAGAGAAATCGGATAAACTATTACAACCCCTACAGTTTG
+
E<22F,7A&51+08.=B/(A;#1BF59,;(.66A@2:/2>10G0)1.427(E1;5/"/@21+;8)@
@r3758
TGATATGTAGAAGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTT
+
80E@5=477-3-HBA8<!D.:2E;).-C:C<&.,CF'<.BH$+/D*6B6##83566&4<00D&5+6/&'#$<&&71
@r3759
GTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCNGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCA
+
:6C%<!-<4(<G3!"<#(14&A<0)5=3!1A9%>!B,FG+65>-?7')%-HA:<G@7*=@D"2;:>(//1#B>=3G;9:0+50@H4"D,GE:G9>
@r3760
CGGCAACACAGGANCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAA
+
,!??(C@B)H:B.52%>2G!6.*-($6#=8:+B.9>:A;?0#/262..G>F*;:78+952>:+*-8H0!5<!,*
@r3761
NGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTT
+
"66:%E$&6B@$5.8H"DD(+:=HG.'G;&0+5,*#A$+C)D.?*,;H5">=B7%4,5H18H90'4%#&5/2;5.-34B,!:24/8C+1EAC9"<C=
@r3762
TTAAGCAGAATTTCTGTCATCTTGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCCCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGNTCTCTTCCCACTCACTCCAGCCGGTCTTCCGGCCTGCCATCCAGTTGCCCCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATAACGTTANTNAG
+
:6%A3,6'/G+9+1G>2$<21B%?B,0&*7G==201F+,)>'1C&+A#&9?''(BA5"*@(B277"31*/:>"-.+'.C!G$-4-*5#AE#H"/,G5H'558>5B,B2<@A&<.E*ED),;C)7*G(7A3(?9:B@48G&8$.7/0:.9H:3'2#+<$!#8)D')<FDC9;=BE)-8"9!<=@;1=4,+'<2%9#3!->A<:B,2=94$<(B33&,2:4BA$&8&9,=4@%;@7(297,4:087//6HG>#1"A:?7;.%
@r3763
NNATGCTCANTGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCAGACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATA
+
&#8(4<3)5&."<%D(>-E$?,(!;9?D@='$;G?+"C51-:G"A&A!E,D4%8H"$#*A40E,1:?)=C:524AG&4#:G09D33'+7"@'>74D4%2H@769+E&>.2$C4$/@3"%8D2D!8:=3=!@,F1>$GE-3"/0<.-$>*#GH48?>2
@r3764
TACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGATTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAG
+
&+&%$##"'$'&$+#*)!)"$#&#+#%$(!&"("%#+)(*%&($&&)&*%)'!)*)*)")+%*#()!"(%'(!*''"##(&!#+'%$#**&*('(&"(+)+'$!++*!$(&#&*'()"!'"%*)+()*$)&$$&$+#!(("!(%)'((('"+)$!*(#+)$(&+%)**$#(&&#"$("(&'$$$(("!+!$$(&&+'%'(%')(("%!%!(!*)"(+&*&"!%#%!*#(*+")("&)%"(&#'+()!**'&%!"
@r3765
GATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCCTTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGTAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCATCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAANTTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGNCATCTCGATACTCGTTCTTA
+
:...%1>(>:.D@E*.$+EC!F7#%,1$C!*3:-"3,>4<:#D>D'D&0<8B#'3F$:0AG?%7GF<E393?3988'FBC!+7@F.<7"/1G2<5G/"%?$0(1%:,>4!'1-591G.BDB.2')392$9%"/1FH-(#9#%-E3=G5=F?,+/93!)0<C5#.';@@+B?F:3;!589<C(1(G&E(7%:&4,#8)-761*<-4,B2E</1).6D7$8,%#!/((@6==2:=.(."'"/4B1@"%;)B9:527438.1G>.-7"4;%E)*"D0E940D<BCC#G;<#.G-??0$D%0-'@',
@r3766
NGGAAATCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTANGAGCAACGTGTTAGCAGAGGCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATA
+
#F:6/"3+">*E./E)9%3*D6@G(6=(C:AG!*%+%6!+&?!F.)C68-%")D8=7=-(CEA2?8,GCG3!,?HAC.-*&5-F?-0?+G5)=@2.>E?E#F)*%"DA&%AF63/#?GA??=:71+?6?@.2#+7>)C6%B<;=3071-B52'"<.5
@r3767
AAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATAT
+
,>D?AA&@,6(DF<D?@<$G-,$(4),8!/1,7!)&5A>)"<'#@03E=BF2$<(8"8F1)7(%&-5$5"7:$?0'F&,C=GB1A/**"@D*29&*9*E%%>$
@r3768
GGGAACTGGCAAGCCATCNCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTNAGCGA
+
&+()#()$%()'))%%'$"+(()!#$%&!('*(#+$&(+&)*$)$(*")&"!*!+)!#'))'!$#$!*""
@r3769
CCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCC
+
>*"2+=5'.%60&?09<-3FF:&59$$C:7G)8-30D@6,/%&>-C299:/()CB9:/@9-(;33/B=3@B9<;7%.BGFG>&>F/*BH)>8$0HF/8**H'+4DB4;&
@r3770
TTGTCTTTTTCTATCTACTNTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCC
+
/6B'-?F$'!D<E5FE>(,@90)#='@:64G*G(?+;#4?70:?.F$AEDH3,GG3%C.,=(@*(BE65"+B??"8A59,9F<+325-"'&H?9:;"=)0@4<E/
@r3771
TACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGT
+
'2#)8GD7"2A3HF3?A"+/6D!(";3#)BCF;21%><06
@r3772
CTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTNGGTCAAAAAGAAGAAGTAAGCACTGATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAGTCTCAGCAAATT
+
EF1,0HBEH/??.*6;+EG&GD#"G:-'9?67=&%)$3CH8FB>(D1)D#1&,&/GCG*$@/G*6(#'DFF?2>/?,@"=()$41C">++)5%)/6;>H8DA35F=E%!%(0>51+7?#(=/:H,@E,5F2FA>47;F.<;$%5?EC%13B8E=G#==;$C+E7!E".4;/
@r3773
CCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAAACCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGG
+
%@6D/1B*,F$86>*:>1-,)70E/./5H8'/0F</,9=#0C0G(.ED5G1.:%9472!?E433!C':?!A8052@8":'%;0F2!::'E*+!E*487G6*0F*$A4)
@r3774
CCAGTACCGCGAACTGACTCTCCGCCTTCCACANATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCC
+
>GF.4'@.#61H?/-F9"5F>#449'#6-AD17("($8GDE),=E5'%<4&D!:5;9'#$7F,813D"1=H85;6DA4"9?,-*-3*(%D(#%,5HC,-1G7:!79CG-?'C=H$$*A@,6,4!10*:B084<@#&3!F:E@:%G)?H&
@r3775
NTAANNNGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGNANGAATGCCAACGG
+
!"'"$)"'$+('!%*++'&")((#*(&(!&(*)'#+*)))*'*'&)&%'**!*+&&)$!$$**+!*(!)+%(!!'%!%
@r3776
TAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATNCCCGGCAAGGTTAGGAACAAC
+
AB9/*5--CA4$3-2%7"29F8ED.+60:4;,4>G871@;3)0"F2!D1##:B-.482$3),4A$3*>$?@?*2C879%&6,8(D="
@r3777
TTCGTGCTTACCGCAGANTGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATA
+
<4-B>.E0440#=<7E-9@#/.14#!"/7.*"%4$>//7"7"GAC#/.??E86$*C'&.DE
@r3778
CAAAATGGAGAGTTTTATGACTAAANAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTNACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAA
+
BF#$((:A*.</B>7'8H+=,#BD-0A-:(4/<E$3@B/H@99=1/CBF8CC928.3<!8;;!6&F37E1&);6?/.&<"?C(?$6!*F#('8+>3"95D74#4B,F3,$?)G?A(66-<$C>F>%HC<A6G5>DH/*6%&/@D!9;*7.7E'!E"%/0D;;$$(85A-*(H27&9?B)(<:28,;D)5EG'&E4A$9*<5++!3AAC.!AH*G'7#15:<?B;-E6&2<7#3B)C7FE/-"@'BD.@@>81$,G?1":54F&AC":--047;:7*:&%;8CB@2FEB?1@@B:%62#39C+?$H"D?BHF@EF.FH=D/.8*31;;6./<<#%CE:EAA00B>&>;1<,H57%E->!!%D;)&?>A'(7EF<4+910:,BC3G3$2*8D-?D'+-$!%37,'B5C06:F7BA:.4#F(.
@r3779
CTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGC
+
9%&GH7=-'?B9DB0.493(>D@"DD090!7&.;412?A7/=)8!C'$E.83?E"?33""<;%+%5B221'6.;")#7#466E7542A.:(*)@C;2')'A.C0,<321$F@6G)>,'65)(C-9$:D=@F.4#+4A'%+0D"
@r3780
GGCATACTCCGTGGATGACATCCCGGCAAGCAGGGCACGGCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCA
+
EB2@$-B$.85<0,8%,%6&9)5BE"=+*@$*'2;D4<.@8<B.)+F&AA04<!B82C:&3A!'/"$:(EH#C<
@r3781
ANCCNCCGCGATTGGCACATTGNCAGCTAATCCGGAATCGCACTTATGGCCAATGCTTCGTTNCGTATCACACACCCCAAAGCCNTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCG
+
E2E-?:;./1"@-9>!H>H4!6F#"3:2@G%C#&8"62-(0%+<;B76F@':G>:17'(6(*G1,9%61)1@:F35@?7&A",%#73*-D82(%$G1>7%!8"!$874<4-@G():>@0&+;B(./$3G>7
@r3782
ATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGAT
+
*,57'2=$/%6E3E*D%1"=2,"/"F91#/F"AB:5C;1*3&<+
@r3783
TCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTCCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGNCTCGCAATC
+
5'&GD/BA(GB(1<B'):"F-C(>?:6'980%C%8"C89#4'4<$;'2@,3<&/98!HH&"8C,B0212C0)1-(H(G>9CCCFG>7FFBH*#!0*$'2'*+#))05F:&*+7+;/(?C&&E6C5
@r3784
TAAAAANTCTATATTGATACTGAAACTNAGACCAAGCAAAAGCANTC
+
*%&'()"*%!+&!"#&+)!*###$!+)%)#&#(*&$+)$(('*&$'+
@r3785
AAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGNGTGGCCTGCTGTCCCTG
+
CA@C7:1C6?G*@@%EH4>:5.<*A>8E+E$??9;:B;F"2FBC4F!2GA"D+3H,4)G4)9$</3@6>C@$&'<(=&-.8+F<-8$G-#*;C!39;.H
@r3786
CTTCGGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGNACGGCACCGNGAAGC
+
<*'(8-1B#-#)E(="2F$3!B4D@-C5?+00>."2$>H83.*5'F83,#'297@;
@r3787
NNNCNNNCGANNCNTNCNGACNTANNNNATCCGNTNNACACCACNGGNNNNNNTGNNGNTCNNACNNTCCANTGGTNTGCTNNNANGANGNNNCNNNGTCNANCCGNNGNNCAANATNNCCGNGCNNCNNNTNCAGNNTANGGNNNNANNGNNTTCGTTCA
+
$""$"!#""#"###$#!$###$"$##!"!#"$!!!!!!$!$$$"!"$##!!!"""!!!##$"$#$!$"##!"$!"$"#""!"##$$"!!$$#""!$$#$$"#!#$"$!#$!!#$!#""!##"!$!"!"$$!$!$"#$"$!#!""!!$$"#$!!""$$$#$"
@r3788
TTCCCGTTTGCCGGGTCAATAAATGCGANACGATTGGCGGCAACCAGAA
+
:2GB>8?4&-D:9'0!.5)A'.!C.(G2(5%7.!'8(9-&C,=.&,5CH
@r3789
CAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGANCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCNG
+
+$&(*#$)+!'#&)#***)*+'#!$+()$)'!"'*)####''!*+%)&'#'(%*#(*!(*+$'"%"*!$#&*'#*("#*)++!!!%*&%)!(%&(($+&($&%*"&!'%!"$)(&&**#+(#$)#!'%$
@r3790
CAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCA
+
#86>:D837E#&?A<CF;;':)CC>"%B!,?F&'&D<B19CBAE)*16,74..2CE
@r3791
CTCTTTAATATCTNCAGGAATTATTTTATTGTCTATTGTATCATGNTAAATGACAATTTGCTTATGGAGTAATNTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCNAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTTGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGCAATAATTCGTAATCTTTTANCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGATCATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAANGTAAGATGAAATAAGAGTAGCCTTTNCCTCGCTATACATTTCTAAATCGCCT
+
6;=>@5A9#G<0G0"(<6.32%,%#512?1&$C4>$!7@/4,D&--E)8!7@$*:F-3;('.67#%-1#(>.C*"+C7051CA%@8578<5(?9?A6%'99?<#1:;!2#%+2#"5(B87(=E&B!E.3*CD%&A"8A>3:=B->-/'!.&:)B;9B@%HH35D::<@79;*?*6!45)@:@*./G%@%H+D6D;//:,:75**:&#%F'7)@&/H5C@8<F1);@E&:<9=6G8+,H"CG)-*GA;GCE9A&59=*675C/+=29,!080H))'4%-.F)E%"<4:0#?&%&0/>G"2<:@=HH4(7$'";:<-)#="8@&E'08A#D&>!D"<.@>H,FD&<)=7'>."-.7("5*:"@&DH%4%$/H@"6A'4*-G>'AC&<#?3D%793.8H,!#$64@5<9$<9(@AH$@)#DHBGH$*=*$4D:?C='=*>>7=509)42A>/2
@r3792
GGNATCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTNGTCTGTCCTATATCACCACAAGATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAA
+
F..+&<.(H&%6GC:<E0"#&@*"15!;3)B)"6.75%=B<92%%E2:87;/H$@#=+#<2?F9@79@?#1@8&B0/E(,A1"975H0$E,:F%'3%3#?6B6&6?!/F8#G..$2*(3!&1H74(&+$--C*!!-,DD?#%"7,.--13@#>!,;!<;%9;87DA150;6"F''01!"B234<A:C/.>FD1,B1',F
@r3793
CGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCNATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCNGTTTATCCCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTT
+
<0,>)?&-8$'1<<+H-:+(EF@B7:15<B/*#71,?"%A.7@2"0":%-6&=+@FGG7&+-G?,*18F.075F.DA55E2@C.;AG+<F,6>C;B)%(/H2'3/9E?G:#"("@6C;C.+#G-07BB$G4)33?0*E4:10$H2EH4*8:3)('<6"-)5%(2:"GE&7$94(0'F,3.;;E)#3),8351#!-C%>2/!(;=<%/AG:87+.96%@=$:!=-B34/'6-.-D3@*285C7D?;C2)=,CB$G*-F
@r3794
NNTGTCGGTACACCGGGCAGCATGGCNGACAGCCGGTCGCANGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCCGCTCTGAAGGCGGT
+
'#&+#'!''$'+'''(&!''*&+"('+%+"$"#*+$'#*%%*!+'*+!%$)%&'#+#!+%!!!'+*'&'&"&&!(%+()'!*#)($("%++%"#'(!("))+#'")#"&#+)*!"!&$%$%")"##((%%$
@r3795
AAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCAT
+
#0$+<AG();$,A4?(G3@",(#A*9D3&!<5%9#.!&DHG>(H/.C4@2
@r3796
NTNTTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTG
+
&$$+'&$&*'%'')!#$!*)&+(*%")#)#+*)$%!'$+(#%)&)$&%&!++"++&#)*)%&)*"%"%$*)%*%*&%!'"'$&)+)%*'(!%*'#'"#&**
@r3797
CATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAAT
+
--<)#-8.D&DC2./0H;,)9:!3<?')71/5H*6G*504>5
@r3798
CTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAANCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTA
+
7C,;-,70B:@B44.<#!'<<%+36"+5AH7!F(/8#/'""20@G,?(G<)4.'+->#56$*$.'7H<A7C6)"BH-<'*>-A<-?F'-03B.C83'7AF3!*B2=0?)4A4>8)#A!E?A6.3'2(?0".C=>?%C0?*D,2;#)?A>1,H/H"/9H+-0H"+F5*;A-?(=3G!4CB.D+&+*B72&$FB7>/3B)+-+/&95!32,E)?%6#5,5)A='
@r3799
TTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGT
+
2:888/;E./%/G$(0D%)G.E')$8#2G9HC%D,6:(3.,G%C*@*->-2F=(=22&4$4$>7275<<DF)A
@r3800
CCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTGCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATA
+
@E;7C:/2@H#2B;(,.%(*)&,AB>C9G5(22A@/4%E)9?2)?C"DF"2934E6B::57@GHC4%C6)@)D%8&/*@#-!2>>F
@r3801
CCTTTTAGCTCAAGAGCGATGTTAATTTGTTCAATNATTTGGTTAGGAAAGCGGATGTTACGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTT
+
AE2'B.D%##F::E)3"C+%/C7ED)-$#;D,5A!C'E+7*86!/#C!!8D6'G2C4,3*6%4C->..<';*.!;H).);("F/C'(CG+@*2*7.6?@*FF;A
@r3802
TCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCNTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAA
+
<AGAE"/G6H.66>&7!B,'&&"!&AD8?,(!C#2H6("-/4GC&%"#2??"12,$)?@!:B8G!;E())8&H3/AD03:?"(H@:7>E%><A+0D@;;(-3?*+H3),H8@/#F3@B3:=3->=.)9E*79<0=%=6(F;GAH!>004;6%,F3E89+<A?&&=+#<:&EF)0++(52.
@r3803
GAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATNAAAACTCGTTCCCTTCNCCAAATACTGTGATGACC
+
.0BC=F:4!&);28CCC??-20*6E&A7?C0=+G/&4F+"*<"5CA)#D@/9(+)92%5>C"1A-6<8G/604.HG9'2E%$.
@r3804
GAAGGTTTTTACGTCAGATTCNTTTGGGATTGGCTTGGGTTTATTTC
+
,==)=.9=F"*%.;!+@,4=?84F%84G>560*F8*3C6$AB8GD:,
@r3805
CGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCNATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTGCCAATCATGCTGCTNACGTGTGACCGCATTCNAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGANCAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACA
+
+'&!!&*#%""%%)$"(+*)'!%#$)*)%*$*'$#!)&)'+'($&%'*)&()#'!'(*#!%$()!"+%%!+)$(&!$"(#%)'&!!#&!&'+*'&)'%)($"&$*))##)"!#!("&!$%*($%&!*)!+(+"('#$&#%"**+)#"$""#!*+'%$*)&*%(&)!$)#"+'$'$!(%&!)$%)!+()*(+)#($+'$"(*)%$#+&!*!!*"()$%)""&*%"+'+*#((&"$*'*!**&""()(*'*&)%$)#$$!)+%'+"#+
@r3806
GCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGC
+
7-F<%&>(C1"02%6<1(32$C-80)G;G)C-7HC?9A-2.6)8$@7G8%4910&-2?@3D5@G.F:2=@,H2/2A"6)*16!*-A++
@r3807
CATTNATAACGCCCAATCTNTTTGCTCAGACTCTAACTCATTGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCATCCCGA
+
.'DB@05.!0&@5AD9@E53>CHE@44G3'#!7F#?E08(!D,=A)5D'B62@*,2$&;$(@*:BA.?C<"%-F5!=-=-"&=E7BE48G'%5*F!668;><>'>.%1:C>:&0:DA''%*!=%@)H@-7/-))%6581
@r3808
ATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTNATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTC
+
D%5D,*>5F3C9B<'="/DC+",D"!HC78!=F%E:-#5:(>5*,+>$%=$<!*)<#3*.2.)4""1&9:+A$"F7*'(4><#4:"A#%70E&)8&EF.1%%48.*<=H1E:(F-,@"FC$*E/G.A24FC=1/3>B;'&E%;H94/=;%=E.;3E))-#?33F,?$)%4C;>&0%1
@r3809
AAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATT
+
4$.(H7F:%4%##!3F*+)B:H7B&GC6-8320GB0=+/AF9H8?2.@:!+">*=3%:*F0>.
@r3810
NGNNTNCGGNCNNACNATNTNAAAAATATGNNCGNGNTTANANTATTNNCAGNTNNGNTCAGGGCNCCNNGTNNAAACANATNCCGACATCCCGNAANCGNNATNNNTAGNGNNGNTGGNNGCNNATTCTNATNNCNNNG
+
$#$$!#"!#!"$$""$##!"!##$!$$$##"###!##""!"$"!"$#!"#!##"#!$"!$$"$""!!##"#"#"##$!#!#!!$$!#!##!####$#"#!!$!#"$""$"!$"$!$!#$$"$##!!$#!"#$##$!""""
@r3811
CCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACNTAATTCCATCCT
+
8?>52%#->59#E!1219H3G':4"9(1@!1=&@D;;!%GD:=?*'60=?:1AA<32C/*7'EAE+G1=+'.;'=3*%?%)"E(9%B#5@'$?'%B)2B($?"85=G>HBF+B"FF3GA6>.8D.,1997=@.8>03H5&
@r3812
CTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGT
+
4G(->F6:0*3-)B-:B>';G+,D:>@B@@8B8>?.?91>,DD.
@r3813
TTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGGACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCT
+
AF5E.?4'28;A2!+.;$A=?11$'B1D)B(#5+5,5@9</&'@>.'*#8H+HE=DF=>E+&/=/.1)0#'BHH!%D,-#.(",)>;,/:=57:HF'='A85C+#H48C)=/;!B/0F!2:;)17H.68,7:&D5)8
@r3814
GGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTNCCCTGCTG
+
CF5D<8.@C'C7(@'/1(D<2>4)H6-#F&7>7@@*0+EA)G.'#!!8##';EG05**G3"8@)178&(,.&H)B3-9+'/"3C>&"%7.F'*71'(H.>5A188$+9;420=D!G1&1E6AD2#?7
@r3815
ATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCG
+
*-D!&;,/-$947$==)&9.67GG<!@()E*0B/..@72B'(-+5#B2A"9,H
@r3816
CCNANNTTCANGNGTTGTATTGATTAAATCAATTGGATGGAAATGTTTATCATAAAAAATTAATGTTTGAATGTGATACCCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTCNAGTCAACTANCTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTCCCAGTTTTAGACGCTCT
+
#)')!$&'('$##'$+&!'"")&!(!!!!!&$*"**")#)"()&$*&****#%%)$(!(#+!'&'&($%#!"($)#)&$('*&')(&#!(#(*%'"))#%')&+!*##)*#"($%&"'!"*"$%($$!$$#'!()%*(!%(**)))!&'!"((!#+!"%+')"+&*"''*#*!((%$#"#*
@r3817
ACCAAATGTATATCGATACCGGCNCAGTGTTCTGCGGAAACCTAACA
+
B>7:$F"@$!*'7$7;-7E.D4.??@?!8@)"*5D8D6D@HF8#53@
@r3818
CCACGNATNGATCATCAGCAGATTGTTCTTTATTCATTNTGTCGCTCCAT
+
'"*&#!)$(*%+'*%)"*&$"$+$)&(%"%#'(&!#')!(#!'(&'""&%
@r3819
ATCAGNGTATGANGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACNGGCGCGGCGGCAGGTTAC
+
!;9GBB+%H5*!H%@(B9G/$:5,-5!>==:7:HG,"8C?>;B0A-;$D>7BE*$,53E0+B7B45=6"?+-)H87.74A4*)+6:="0?3:"%68DE+,)!D7
@r3820
CNGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCTAGAACGC
+
'&@;+B1)@FF2A!G>C*8$78?;#*5#!:#.0=)4,3'1)7."(%C''C;*.95!#A#79",,.
@r3821
ACCGAGCGTTCTGAANAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGT
+
-E$@BAF,5%B#)4,"9!1.!+B0%6=G"#=%CE+54/B7/:E4C'.&?'0E#668B>94/=4%
@r3822
ACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGT
+
8E7CE4-8F!/?>::@8H-!*@$C2)0%(!$+:FG)%,>/-+,:2/*7%1GB3<E(>3183/1/;(?'#
@r3823
TCAGCGNCGANGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGNGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCA
+
G9FD%-"/@9&2?G;3(16B!G3,BG534>EF@@G3C!28C'>GE9$-1*G:';/.G6+><H$%0?)!?7;C/%C0;,&A;>)E7"1&C?=3E/>(/;-74;5CD)2'"35012G1&:):FF;)$*AF/)F>':1<F@75
@r3824
NCCGGNAACGTGCTGAGCCCGGCCAAACTNCGCGATAAGTGGACCAAACTCGAAATCAACCGT
+
-,96!5*F<'E:3A/0#96-)32>%*FA*$A49H!)3(=-+()-)#:9:0-3G<?>@/:+<7$
@r3825
CGAGGGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACT
+
*&%*"+#*"*'#%"'"*#%'&+()"*+'(&%*'*&)+%*""&#"'%*%#")(%"()#%(''!++)$("%+*'+(!$&'*!'!""&&(*(*(((+%$&""!)#&)"+*"'+)')")$$"%$('!+"))&!(!))+&&%+!)%*+
@r3826
CTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCNATCCAG
+
2>,%!:.=5</H)&0=***640-2953AE52+#E:=CH99;<-9E;GE#'$B;(HAD*;
@r3827
TCNGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCT
+
'#$H?*(,=H#4&2<F):2F2'!,0=@#$*2?4>%.@;74&9;C<*?@G53.+<>)@;/(->@A<G0F.5,D")A)+C//8(@!6!-'D:*-'
@r3828
GCNNATTGATAATCATCACCTGCAGGTTGGCTCNAATNATTTGTATATTCATAAAATCGATGGAAAAGCTTTTCTC
+
)&")&*+&$!%!+'"$)!++$$))(&&#+&+)#)##$#(&%$#$$#!%!$&!&*%)#+&"+%%$%"'+)!!"(&#!
@r3829
TTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATT
+
F1HB1)6??7D6203@??*+<ED*>C%35-6=8;F68+2/$470B92"*#CBD6)>,.CF6'&?GD':A*9@:?H,B@:?-+*G;5+(*"-G)7=!<(2/%4,%8EH/&89)+:4.$+"@C25@"-G$!F3)8"9*A%@@A%A8+.>BD>"0$DC*>B*(8A3
@r3830
TATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCC
+
A%+,1,'B4B!.(5-12E0;G&:BD*;5@12D&0)3'G3D2"/-=58F0#>A,
@r3831
TGGCAACCTTTTTTATATCCCTTTTNAATTTTGGCTTAATGACTATAT
+
?=71CB4.F;AB:E9#C:5D0;-(#(,""&3!0B5H<D,'+)>>,88F
@r3832
CTCNGTGATTNGTGCTCGGCGATGCGCTNTATGCCGGTATGGAACNGGCAGACGCTGACGTTCGT
+
&'&#*!''%#$"+&!'"*)!!#&'$#$"!(&*#%%&*)+!"%$"$&$!"%!'"%""%!)$'++&'
@r3833
TGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATAT
+
G?C.)%;(++G36;31.D8/B,0@%61%BHB!2!A=FE<FG/!:+E&A$H+4)=;+2)B(5C=5;!;0@1-.#:B5%(-8"2.AA6;>.!D)4,?6,#/@*)19=6%C
@r3834
TGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATG
+
-F9>@A"C77'E62'*DE1?<)=1E>1115>1<&-A!5+4..A10!DACA8=.5%C;.1/C">>6A(*+9'.H6?2#/+#E*F>#7H>AAE-&?:%+B)E)A?A38:3C)#3/*77-C898H
@r3835
CGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTA
+
7&E1%#H0>%D.D0$/GG4-657*EF@)'37#&'?H'-*EC"4H52?$D-1=BG*G98,.1CD@;,4%#4
@r3836
TCCNATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGNTATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATATTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTG
+
0GE"CDG),5-@*<">#'B?%3$35%(A/)8=5B%$?"6C.A:BH2@.>'F="6?*,3.!9=D;2+!/E8!A("!4C(H4278/1,+(!"8F1D4'B3!=+1,D+8*$+5;FGG/(3A75,40+?6:@2!9=:>:"@343H%!).!C5<@&,7>;'B8.)'*,B)-:!?/3#B>237"FAG6,/&:842##<H?2G"F1@E13C/;!2(+09<1>7171G&?/<>G@#"/&21//.,3+8
@r3837
CGCATTGCATAATCTTTCAGGGTTANGCGTTGTTCCATACAACCTCCTTAGTACATGCAANCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATA
+
+*!"+(*+!%+&!+&'+%'+!(+(!"+"+$%&+***)'%%()"!$!*+%#)($*!!%!""%(!"%+#)"%((("&'($!*#(''$'$+'))"'(#$*#&!!%$%'*(('
@r3838
CAACGAAGAACAGAACCCGCAGAACANCAACCCGCAACATCCGCNTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGCTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATA
+
126-A;!107H=:HAF>0%AC./$D,*8@<-@*+=94H82.E2?65H(E..+G'?8="/B.A01297?7&;@<=33?21"A(D".;>>('-D-/45/*))E9+":(3'&1&0=A4)@#%2E;+):2&<C"@E!CA!A<*//@AA.0;E6*&*;3C,=D<HA*E
@r3839
GACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTACGGGGATTTACAACNATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCNACACAG
+
.($8G0.75713FD+8*1*?-37':>?(46E!&DF-:02&<CA!1:>?D10.:C4'57%)6GB725/!D$8)6?=>)9>1)+=E@C.E")-B0+)-)"=0.40&!G;3>8!;7D;$7<($&89(H=>4*0;A:
@r3840
ATAAAATAAATCCCCGCGAGTGCGANGATTGTTATGTAATATTGGGTTTAATCATCTNTATGTTTTGTACAGAG
+
77@@:*,*&G$')7';":=.H10*C+C7/761A512H92-8:$@%.>?"6'*H3,C159+<3C$,%17G?'0B;
@r3841
ATCATCCTCCGTCATGGCACNGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGCTGGTCCCGGCGTGCGATGNTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACANCCATGCT
+
;'2;6*.=?)C:?EH*HF#6&7HE-/H!H3*HE.+'H:4G,%+48AC":BD'>''-)D9%:5/(+097-9$B1,#0;B$<"*01A<HBF?30G77!;9&!*A@)96+:!14%);?)GH*2B>3"./7<4;'C$16&H.&.%,,%
@r3842
GCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTNCACCGACAGGGGGAGC
+
5(9!+38=FB8@39-8D.H'2-F!-+-8B125,6)67768>&>+"1:HC59':)A$$8'DC%2$7&;E">-6(6C:$6F=(BC+F8;=?D7@,A$6*6,<(6*/*&7/;75!<,E:380$@&;+"DE?D//%=B"4%'+:5.&8(8?H>#/%1FG%03!:DB
@r3843
TCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATNTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGC
+
#,2FG$/59B?F)4;3BG=2!059);C<E!3B/);(D@C;BB#=,$8&*'E6$A:>!,/*.4=@!8";"(9,;)054)8-*
@r3844
TCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCNCCGTGGTGAGTTTGTNTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCNGCTATGCCACCGGCGGTTATGT
+
8&)3*A"224<;3>5%71'?/%EA?0H;DC=!/!C57DH<9.'(-(*"2:@.@&%ACC>&*<>/,D;!;(E>=F-,B$@A/37&**>E;B+@C>G?+=7%G<%+(-"&3$%%)(%08G'1(H$)+@4B$$#GF'B1-<.G.$2;()GG>-AAC>8+3A3D6G&+EA99!E$0=78*6&<@
@r3845
NTCCGCAGAGNGANNNCNGNNCAGNCTNNTANNNAGNNNCACANTNAGCNNNNNAAANG
+
#!!"$$$"$$"###!"$$#"$"$#!#!""!"##"#$#!!"#!#!#""###!"#""#!!$
@r3846
TGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAANGCGATNT
+
/*):3;21B"=@7=*>*E?CF92!:8<-7*:"8=FD%(&C*1)GB?E4$
@r3847
CGGCGCAACGTCGCCAGCTGTCTGCTCAGANGAAATCCCTGCTGGC
+
5?):<+.E,?="H!&.:E18446)B2HHD0::"6=(G:?.%&/(>8
@r3848
GTACCGCGACTACATTTCAGTCTGCGTGCTACNTCTATCTGATTTCCGTATGNTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGT
+
'+$(#&&*$!#+#&#!+$'*$!#%*('*+#!**&'&*)!$+'+$")!%**'$%(+++%%")&(%$")**&#*'#*$#$"+%$%**'!+*!$%((('%#!$*%'!#(''%*($)+""")*!$(!#$!+*"#*+!%)'&"$*(
@r3849
GTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATNAACGC
+
HH6H(!D4",7C)8G#12C>/$&A7A!D?4D:207,=B07<0<7!@<(=E-#8')#>H=(4AD!1014=E%=G/2)E'>B&=F//,E5&:!$=50:35-@1-A-$48<)>E
@r3850
NNTTTGTCTTCACGAAGGAGGCAACCAGCCGGNTTGGCGTGGGGAAGCTTTACCGGCTGATGCGCGGCTATGC
+
!(0ABE#EB-D&@<E$)=A56CH)$'@G"FC%"0+."!G(=+2&%..39?@15.)*75">EE(5:<;*!CFG:
@r3851
TGAGTGTGGCGATCCGATAGATGAACGAAGACGCCCGGTCGTTCANGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAA
+
E?#1H$#8F:2D#F,BB+:C<=-%<@AD(:C'*?,GE,>F+5C64/1'09A01/4.AE(5D1B22*E!09!)$%+2"44;1:2A?
@r3852
GGAGCTTGGTGTGTTGAACANAACTTTTTCCCGATGGAATGGAAAGCATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAG
+
.EBDGBCH:F?'<%,E@//:7,B'BED6&/AEA/--,<@9(&:8"72%1E>**%;>*18-0.,D9;9-E?'F8CCDH-+:9#E4+79-!FE()!5E
@r3853
NNGCGGGGTGCTTCTTCAGTACGCTACGGCNAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATNAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACA
+
&'!#*+$!*%!"$"#)#*$#+%*"%*(&!"(!#'!$'"!)&)*(&(&()!&'$!$"!"!&(+(+%&&#$'**'#!)"*'#+!*'%$*"#%$**'"!*$!++)&()(&($)(!#&)'!%'!''))"!)&'!'!+!(!#*#&)+'
@r3854
CTAANCCNCTGANTGAACAAATTAACNTCGCTCTTGAGCA
+
&($&)&)'"*)'!'+)!$'))!("'*!**'%#(#''*"()
@r3855
GGANGGGTTNNAACCGGNACNNNGNGTTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGG
+
!)&#$$!*($#$(''###%&(%"#'**'+(&+'+))!$!##"'""#&*&($'+""&$*)$((#$
@r3856
AAACGTCACAACGTCTCACATTATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAA
+
,)59'89F0B#E9%>/33*B":%*;3H2AG%&*)9&/!C:FD%>/7C&!3;-+66@C%@0(C>=&D95C@1*E$&'%*B0=>@.,(:F
@r3857
CAGTCAAACTAAAATCATTATTTGATTTCAATTTTGTCCCAC
+
(7?:=?;3H:=B3B"--2+0466);586*5FB57B427-<79
@r3858
CAAATATTCCTGATGTATCGATATCGGTAATTTTTATTCCTTCGCTACCATCCATTGGAGGCCATC
+
27%!3=D;:'E/8&#G?415GD-!=7*1HHD4F--048<86$$C-5966B@7F=1@&&*8',;H7#
@r3859
CANGACAAACNTNNNTGNTTGTTANTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGG
+
*$%%&%(%"(!)'&#%%!"''+&%(('!+&%'$##+$!$*#++!%!%!%!!!"(#%(!#('**%$%&)
@r3860
GCCGGAGATATTTTAACAGAACATTATCTATCACAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCT
+
9*7(*5G0&#3*=,=;&A8F&7?EF79%1-:4'4+?9D*%*(@!$CCF:"!&-2:;"05$)4"9D9=E4*%79*5;?A
@r3861
NCCCANGANAAAAATGCTACTCGCTACTNCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAA
+
'"&$))')!+#"+%+&&('$$!#!'*"%&$!)%%"#+*!!+&!#*""*($#""&'+*$%!+&+&%%*#)!!"&#)()$*#)%&"
@r3862
GACGGACCACGACAGGCCCGCAGTTATCAGGNCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCG
+
83G?-)2@C28$048$0@"&-?B7'H#A?#*8&F(B0A=,4>2.2D):G"$A9881<AD63.G.<C961=H9-=!"34&-$9!46A3;%15HE#&F<&':;@B:/<2HH09G9,93(/=!*-$;&/=85?17E
@r3863
GATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGCCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGGCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTNTTCTTTTGAGCGATTGCAGGCCAGCTNGGGATCAGCAGNCTGACGGATGCGGTGTCCG
+
5</.3')+94868:,;H()'8?!1DE:914(@*!"(<7+H"-?#1<$1B"?:?6'G+3+0@72+FC;+F5;A7+B:!".6,A'!GG;#$.&<!+E8:B9;,,A;D+&=#&A>4502-G"&/:)>+5H)D.8$3#8.A5C"?:+"D7"3<1A&7(:)8'<;F;765;%9!'(DE!;=B59B#*$3@<H?@:->@F<47;+<C4*>4=51!@'%%</A(0/3@,8&--7;;<@$2C=G%9>%3E+B!<E6>!.()41/(D,19$*E1(0<CH6,4@1F?/68/0-!<0!?H"$6?#5-0+)G&!H<&7@65.A$8#30*0G?$,7=$E$
@r3864
CGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCNAGCCTCACAA
+
GA(H-CH)+)>8#><,>;.+84G*=/'!&:>+C0D8!1-$'(GH<DF/,-%6'/+.4//'5E1?%E-E,1C'D/$'")9%.(>1/8).@'6'86CC<HE:--#,43;3#F4,E8<3.@9C=DG@.1=227/C!)=9<0,&?D.2?E
@r3865
GCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAANTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCNCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGNCATGNTTTGTTGTTAT
+
0FA:A94><+5%B5@0$9,2E5&:=6>,BCG;48"5+8)40/3.6@-G*:E1&,&?0"/C@H4C&F#$G>CH31$A=6%$0'$94?7'$#68)&C8%<9+8<"*(9/D<B*9@4)*4&1##.E0#D72H=?&BB#,*+@4
@r3866
TACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACANCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCAC
+
7G#A,6&,+G>D./@*3/#)EG;!/4()!H:!,&#2;"C-$EDC+<;.97A%+&G+5$.9$9=+(0F13>,B03=9*68*F+7E0!#'/#!(/0-">/$*#-%,!53=<"B-%(B>@3($5,<,$1+1&BE5='(:H>A;AF2?>?@@0BB>D>G#,=.DE:3G3@'E-&&=70H,3=<=G<8BCB"E:482;E,>132A%>&80+G14363B*1-4A@$*?@:8",2="$!83;?/G"E&.',H'3-4@."-%B+%D"8"3./0C#305&'@1>%&+&3G"&!F=1E
@r3867
TNCAANCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCG
+
A,4CH$%5#1::F=!B<?<;:B&C<>C0$4HA&-D7-&/4A3-@2%*%!=DD;:@G2@0D&239D!7GA&00@D/0E
@r3868
NTGAATGCGAACTCCGNGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGNTGAGGGCAAAAATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGA
+
'F(HG5;0FB6)D0DD#?.'1-1.E+"GH3<:H@GC;'.%6;AD*7-.)!'4B@GE<=8:1.2%!-&AG%$>','73!;8HB3$.44+*/#&><A=<AHE(>;8,,*?%&E57(F:H2&+2#&,/@#$>7;E5)C"()99+3<
@r3869
NAGCGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCC
+
$('"*)(+$%(!'""&!$%&!&%"+&%()&*&'&*+#"(&!('
@r3870
NACTCATGCAATTATTGTGAGCAAAACACACGNGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGA
+
&5?D?)F%-$5&%8'7-5*#31+:#!?D%!C5<E@D;"@8'E7)1B9G>!"*+#-?H5E</'',)4F.#>#:<?B)!>7-;2+4(96-D
@r3871
ATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCG
+
E78E6G?DC&=#A1./.=;=+<36*-837H?246*D'&,;5&;HF+49F(<,)G;)@/:<5-$/5:&:-)5G>G;6=HH#F8#?0'&0%H&8="0C%>5=..549D9,!#:6!'E;8-32B?=5?:
@r3872
CAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGG
+
@@=2$,,E5-%,.2#)-D270.@)@,A4.5H7C8<HDC8CC*3%;&&;$!82)59!@GFF8;/2&2%10A%66/=1:<A'D.A:/#3G+H8)%07-"#
@r3873
ATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCAGCATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGA
+
HCE$F<#.@2.2?@E.($<HC@+"&)#%8-1G&0'@>H0%:F&9D0E@G6FA&A81%,,@3*90:&2,<'C5G4H",?"E7FAG=C9AG4/54-.+.>B
@r3874
CGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGANAAAGGTGAGCCGGTCACATGGC
+
7'()C45@=)$E&-!"2(&BA?$B!4?C#*)0/D.2G=024/H326*1C"&*0DE:.;D"!C
@r3875
GATTCTTATCAGAAACCAAATAGTAAATTAGTTACACAGGAAATTTTTAATATTATT
+
=/?DGCCHB-//939>E4:89?H=&5BB(F25H+.<4>&')$$:)76+<&08-,26:
@r3876
GNGCCGGATGAAATCGGTTCGCGACAAGTAGATGCAATTATGGTTTCTCNGCCAAGAATCTCTTTGCATTTNTCAAGTGTTTCCTTCATTGATA
+
,518G9?/>;6G$(5CH!?E3/>>4A,'6C>@?0-4G<3B@)54+H-8,2H>6:*<F5?;?>1/.3"9:?$,33:HC5>%3,23B6B<+;>:A-
@r3877
CCANATTGNCANGACACAGCGACGCAGGGGACCTGNAGGATATTATGTATGAAAACGCCCACCATTCCCA
+
!()"&#&(!)(*+!**(!!+(!&$"&#()%%!'&"+*""+!(%%&#(#((+!"&&!!(%"&%!'*####+
@r3878
AACAAGCAGAACATTGCCNTGGGCAACCATGTTATCCAGTGAGGAGAANTAGGTGTTCTGCTTACCGTTATCCGTTG
+
1H'34-$3@&F3*(31-?@@C:(B;&<00H25H(=9B5H#'-E+;#,2>GA&1G6143$+A#6GGE'CE6HG+92)@
@r3879
AACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTT
+
BD3%CC!%<!7*">),#,<EE8::;+6.!$+5E26C1:F6*F/1B';<A
@r3880
GCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGNTGGCATCACCTTTAAATG
+
,7G07B72;3$@$=4?80*)1FE8+(4'EC&8;@B18373<%G!G4%%&9")@+(.G=$%$4AG%".F<8C0DFB((?$"F,/$=B0-,)G,0D
@r3881
TAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCT
+
'+)*#%'*(!$!%)"*!)'$"'$"+"'%("!"$)%+%%(()!+!&$%*'&($$(%!**$&#%!%%+#('%$"&"%!!&#!!++(+)#'($$+
@r3882
CAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGT
+
9HE4B(E21F697E30+#G%%1&<AEG@)&H&1!7CBB;<@3D$75:C57:D<%G,>5.5A-D':A%D$%$+,6*0=:#H<CA,&B03?60?%H8?G
@r3883
NCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTC
+
+>?,B';'?%./?B03$CC5(&D$CG726F8<1'7)('-D8@E!
@r3884
GTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCG
+
:;?*3.54>H?7F=-<A.E>@.6!?0<G<D$<105BA61!<1+F'?
@r3885
TCGATTGGCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGCNCGGCGGCAACCGAGCGTTCTGAACNAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACANATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAG
+
5D63(>4A01.G?HHA9&">69F(#H)C<=)1)86386!=?$*8=2H!9()/-H7;"&<=+?6(;(5.1#F6>6:!>8(AG1F*A0D8"!8),&?/3%G-!9??%0A>C,7!33$B:@%HH189'F9#8(H;92E2>AB$"0"585>B6>F>#;4)D7>8C6-1E:('A.7;%!:/90:H
@r3886
GGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGNAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGNGACGTTTTTTGATGGTCGC
+
C/--34"A%D#)*?!"9+@$9'/:B7(2G/G<8&#.'(D:>!->:+H($0-H=(C>H<8!$%<9'&*%2C'-G%%@@%+A.3%>(B"@A&?ACG29B6&E406212H+5CE&G7?&?7+912%68A"*8+4HB?7)&?-8<AB9@@%?BA#./C(HB3:F4,9H4,G1C*@1C:F&!*.)A&"AC@,'>?&-9+4B#,G;0A&;6C'6!2;
@r3887
TAGGACTGCTATGTGCCGNAGCGGACATTNCAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCT
+
D'E52A59!A@3DG/'#()94@&C8FC(<7:D@E>%$**C":6,:$B)*&*33.<!<$)!57&/H@'FAH(1*?@@F-);2,"3H421@!0C@)@BFG$9.9-G79;F8F.54::$3*=C2F;:)-!<8D00=-"1G(':=)=0&2'CF82)C4C(C;:!&%9#(7/4"AEE,C&6=F'"@G-32-:$?,3/;%2
@r3888
TTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAG
+
'*%F3H'0>!,7)5"-D<7(.)2%<&E,E,9/-"!90@345?+7F8GE*76'/</8+
@r3889
AGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGT
+
/('@,()84DBH!ED!G0E@;5=>A1C,D796,7/(.3>51;!+1F$D
@r3890
NNAGAGCGCCATTGTGAAGGCGATGTATGCCGCCANTATTGAGAGTGAGCTNGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCNGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGT
+
)*G96=%EC3.#7&G+119;+4#;@/,:<41G!/#!.BD5#E:-0F.4/>C$<27(%1!E<8/--02<'HC#<?'*@>#="?+D7DH-6E9CGH1:-(=F,"/8/,;=(C,)>'+@@/6H.88%<*FF%)!?./"5+%5%<G%-7@0E7227)!$39&9.73F#D(?;5D$?#13)&)@.=62+';8+@6;8?=)@#@(+>G
@r3891
GAGCGAGCCTGGTTAGCCCGTGATCTTTCCGTTGTGNTGAATTAAGCGAATACCGGAANCAGAACCGGATCACCGAATGCGTACAGGCTTCATCGCCGCCCAG
+
!+"&('%!$'(+#"!*$&(#)$()%()%*)&*%+'*#*$%*(")+")(*+&"'*&)((*)!""(%"'*!#$+))'$+%"%*+''&'!&*"&)+''$('#"$'"
@r3892
GAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGG
+
806!D<:0G6/8-(((F+B77#2(A;D8(CC1D626@9BB4*;>!+(7E"?,(DE'6DE8?/!H7(A=-8.@3>=)/-51C,.
@r3893
TGGCCATCAGATATCGTNCCGTCTGGCTACGTCCTGATGCAGGGGCAGGC
+
!H1)A79G.D>6/H$7:.CG/):=B/+:D>"3&H>(?DB#?!!@FGCA-#
@r3894
GGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATTTCCGCCTGATGCGTGAACGTGACGGACG
+
8?3F;@*4DG:D15-C'82@/*+&E2<.:%(F060;(A=>,A"=8"2"!45E=9)'.'<+G@2FE-%B,$#/@6?<)B')E"2&?,5
@r3895
ACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCG
+
7?AF=&E+E4'!+:1"9C95/+4(H?355/,3+*!B=D5@F46D:(EG"7?#/';:9#8
@r3896
NGNTNCTNNNTTGGGCCNACNNNCNNNNTNCCNANNAAGATCNNCC
+
"$#!!$#!!"$!""#$!!#!##!"#"#!#$!$"$""!#"##!""$#
@r3897
TCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTNAATCTTCATACACGGTGATGGTCCCGGCGTGCGATNGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTACATCCGGATTCTCTGAGTCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTNTTCCTATGCCGTCTTTCAGGACTCCTGAAATC
+
(@$)7H=C1'.D2/0=:%B?H(6%68**54CC+2&6FFA.19<"/G07-:-D'E2D$,090#C==8$4D+)%:9=H+GHG31)15)'D(;$'60#C96/C$@>A0?!BF:2+4(2:HC'$+>"A0G=%)2%G4H&=42+&%C28=6'*>C7HB!('=):1F7B1B;*/>E75H$;C;D,),!6E>*&=F)E.1%HA"50!%$)8'+DE/$<F>@1-E"FF4F+0G=E!"(;A(H5'B(<,E$4'D;80":99.$0G82:%5*%@*D"!/&?&&'&%';B
@r3898
ATCCCGGCGTAAATTCAGAGNTGGAGCCGCCACGGGAACGGATAACCTCACCCGAAACAATCGGCGAAACGTACAGCGCCAT
+
=H*2H>E+<9.$%A"3/&#<9H8/%$E@C:3B$#>0/?4&)&48H.8;F6.'G297#24$,9,2(=/3F$CG752$7$8#A=
@r3899
CNACNTCGTNNGGANGGCANTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGNCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCTGGCGTNATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGC
+
$#(*#(!"#$$"*$''&'&'&+'#*++$$#!&(%!'&!!+(+#+#'&)$%'(%"'&!#$")!%"(*((!%+$##!$!*"+(##('%+)#'*)$!*)$#%+&'+"%)")$+'#'$'(+&)%$*+'+"'%&&!)!!#%'!%)"*'+*$#)*)%)&$!+*%&*$$!%&##*"(!'("$''$+)'#)(+'+$")$"$!)&!$#"'&"'*'!&&#+'+#(#"($!(!%(%*!)*(++**!'%***"'+$($$+(*+&$*(#()'+'!'%%*%
@r3900
ACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCAC
+
9A0-BF<D#B%;8?C5A'++!G!A'/'G.=C-34/4>''E3;7B>+C<*D+G,7$2,<#8(,"(1BD:G=A53/,
@r3901
ACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGNTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAG
+
>?)'F?G97=0HC9#H*=+(3;E=;"*H0A;$)(?8)@$553=5</C%=C=F<@-8-(1C8D?;-;FD5G&@>/9>G@(&.:(!B)'C,#3@->!/>>.FD4/$"%3?#<..=%G:'2#1F1&(8<+66-BE@*F"')$802F1#&D=*"5B)-1;D4G>'&5/,8E"&$8=<"E"<H=B"==A6,<.4$A2#3E,1F6?8/+0H/4:.,EB,2':($C(H)@2/4").<A4=HA!,5"6:G36#*<
@r3902
TACTTAGTTTTTTGATAGCTTCAAGCCAGAGTNGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTTTAAGCG
+
1+-1;=!H@@!0+8EE16-E:E-7;G0G/5@A#'/@1?1;5B#//):??,GDD"@->7:@><661C'G9!)4C86,8#D$HA+!4:7%
@r3903
GGCNGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCC
+
FGG.%'B%!H4C<7!F//,!E!G2H6.?"H:=)$)D+,$;#E?(%!F4H48-2C1-C192F9*4?H7,="$"1C&/28)07=D2E',@;&$6A?23%@#;7E
@r3904
AGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCG
+
.(DB0=B$$0,D?#A+C-5$AF+5A#E7B>**C*6!5:($?FE54C170<9;$4;2?)(!<%&3,&=8C"F)9B+*,/H;D19D=9<0(26D8F'E')+*7==A,,F+A@8,98"5"#;@342
@r3905
GCGATGCCGTTCATGACCTGATAANTNCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCNCGAGTGCCTCCTGGGCAGTCAGGCTNTCGCCGGACACCGCANCCGTCAGGCTGCTGATCCCAANCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGAT
+
EH+A."96@A",3C9,B>?>0)1CC6:(:5.:FE)>;@+6&&%;48'=A><B3G"#*:A+;:<=(G%=+/:!1$@<$(*87/>9E"3>/F#2/<'(C0"$A%<-)1?;@6$E*(=A#HFB%C8/@"(1%83E!.-F)1380?E3$1A:*5;4*2&2))*,>2F-'!B'<7,+?(!+*%5:D)"C/$=H'4#-B,!*?-",&3?3G#)3;HDB!4$-7=H?D'.G2B4"H1,F"$;,/!G''>=,7FD;F?2'G#/)BBG('*/"1BE>
@r3906
CGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGA
+
:2%9(-'H&!9<)&(AD-24G;F!$:2#8!:;8;*BC%;?7;,<"GE.-A(+&>>320A*$7-E$F>1.**
@r3907
AGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACT
+
#3,%*>9+1H5=$::E!9B(;#%A?,(:-G#B-%5>#?&$A&?3C@C2B&;#=$5A;#98#F$1=5$@==$-*')H4DF1/%@E?.1B58-B3-AD%1,41/!4&,63@#2/6.E3'@C7!$(;27*9-
@r3908
GTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATNAGCATCCTTTACCCTT
+
DD7##"'69H'8G9-H233D,865FG.HF;9?E+0$47-C9B!FD7>6!1E=G==>25+#D<&FH';7",41%&:9<@;.H!7!?(:0H!8:=%C.)E&#);H$=3'
@r3909
CCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGAN
+
7>?">1EG(2B58/'+';%-E66BA7/G./H:GC!2((-2G#;08F(7#H1=/D&>-@3@)@BB
@r3910
AATNACTTNAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTNTCCGACG
+
'%*%*'&'!+*$%"((+(&"&)"!$*++$'"$*%')*)$**$'*#'!&)&#)*("+%"*!*!%&+#!"+'+#)($"%'$)*(!%*+)'$'&*)#!%+%!%$&*$""#$&$!#($)*(#+#!*)&&%'&+!"$
@r3911
NGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGNTAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCG
+
'*A?35#*";?@#C,5)@C3,=3)/;FH99G-9$&1/2?*C%:EG>%"37%;6+.F8<:"7AG5C8A6;?1.)1/.D(921=@)GG?#)#E#,51;CA;+A%=E("D6='7<0>*/$F2H=/D4?4'6*"2274?(H#1G/6
@r3912
CAATCGGCATGTTAAACGGCNTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCT
+
8(+<G'%!$C!;5:,6!/.6@01(@!?='=?F>1=,/5C.F4/EA+<'"5%$0D87-$!B4E.E-()?A@BD!1E,
@r3913
GTTANGATNGCCCGCNGNAACNGGTGGGCTTTTTTGTGGGGTGTATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGNCGGCACAGGAAAACCGGTACAGAACTGCACCATTCAG
+
%$&'"('(%%)%")'%'&*%#)+!%'#!!*+#(#%&%#($&$(&%!#"(%')%%"%"##)%''*)%#("*+%!"$)$!"!$$$"+%*!'&$$*$$!%!'#&'"%%+#)+'))$!*
@r3914
CACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTNCAACGCGCACGCCCTGTCCGGCAT
+
<#;*7!!:">4*!C*#2?GDH2(,!7!B$8$%(.G$>'C/B$8$,B5<80*::FH5#F->B2-8=
@r3915
GAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAA
+
8B,2/F"H(3<!+6,;89HE#*7H1+A3'A@>8F6$30DF1(-A8%-6">AF7A132F*'91?;CH$==EC088C?#+67@06*&=";A//EG<
@r3916
NCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGC
+
,,7C(8A'6H&"&#-<(7F4B!059BG$,F779>:457;-*,/#,@93B5G10"">+C#FA6,</D1!B:D!@'+HE:.@37.2?=H):<5!1:0!0#&A2@+8>E%-+H#;&6D68@CC?+6AC$H/AG2C29)
@r3917
ATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATTGA
+
+"!%+$**#*(&)&)+"("*&""%!"""'!#)&*)++"())!"##&&)&$&$
@r3918
NGTCTNNTNANTNGGNATGNNTGTCNNCCAGNNNNTNCGAATNNANTGANNAGCNNGNCGGNATNNGGTNCTNNTGNNANNGACANNANGCNNGNANTGNNCNNTTNCNCANCNGNNNNNGGCNTTGTNNANNNNNTANNTCAAGGGNNTCGANNNNNTNNATNNTANNAGNANNGNNTNTANCNNNTNGNTTATCGNCNGCACTNCCTTNNTNNAGNNCNAATCNANTCNNNGNANCGNA
+
"!!#"#"""#!$$"!##$"!$#"#!"$#!$#!!"$"!##""$#!!!!$"$#$$##"$$##!"#""##$!!#$"$$#!"$##$!$#!!$"$$$!#$!!$""!"#$#$!$!$""!#"#!$"!!###"$""$#$!$"$$$$$#"$!$$#$!!$"#"""#$"!##"$#"$#""""!"!!#$""!$"""##$"!""$!"!#$!"$##$$!#""#$$!$!"!"!!!#!!$$$!"$#"$$!$#"$$!!
@r3919
ATTCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTNGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCC
+
D244E00.D8H&!B1?E3;#.C$HG5:=7:*>BA8%7+;"%G1(!HCF1,G6%A&)4,,H:<30!-F#:?-&?7&B9?*""=!89+<F!#C"0580*5*3@(
@r3920
NCNCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACGGCGGATCAAACTTANATTTGTCCNCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATC
+
'#"+)%*&"$)+&##"$('%!'")+&#'&%"*)*+"#$(&+#%+%"+%(()$(*#)++%)#*)!%#')#"+++#'!!'%+!"!$*"'"#'*&##)"#("'!%+!#'"##*%!"#$'#$))+)#(%
@r3921
TTNGCACTTTGCTANATCCCCACAAAATGGACATTTTTCACCTGNTGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGT
+
(#')#&!")'!*%$*+(+%)((("")!+')&(&))!&''('(&+(*"+''#)#)"%""'$++($')"#%!%*!"'$++&"*)
@r3922
GAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTNCCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGA
+
9C+2=,242H,&%:79!D85*D")461#4!,$.1H2$-1(&;<)@3?-B1(7';.,<"&;70*#*8/'2=2"-)-=<0(5DG@+#:G&@?)764F39)9.8+E7:FD2AE==)(7-*29"$1/->G3.2DH
@r3923
GGTCNTCCTGATACCGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTG
+
2C()=60"9B1EBFH*5%#3)6<?+#:+2@*#$)D@09/)#0@3F>D30*6'?#F2?5C!:76?##;H"-#!95,?;H
@r3924
CATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATTATCCTGAATGTTCGGTGATGCC
+
!2?7%C;>E=?!C@:"-D;/1-*F::1D>36*,@H8E@H,,G&BA.DD!C*><2!);"=.-3A&E"*2F*@8"<*)F'(+5!)C"0/&
@r3925
CNCNCGAATAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCAGAGNTGTCCGCTTTGGCCCGGACGCGAATGAAGTTAT
+
"#!*%$)&")((+")+"*)$$%(&')&&++%$'!$*!&("(+)$&%'*#$%(%(#++'%&&*)%!'#%$)+$)%))*!(*"+)%&)*+$+&
@r3926
GGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGNTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGT
+
57%0&E(;?B62>)1$%D.FH*)%G)C=(A,980/0B/EA-$GD),),>C%62D!*1?);'81-@.*:@;-&1&.A+-,82C;*$G:7"#:@E*>')D+:G920''>41!<>$C45F
@r3927
ANGNAACCAATATTCGAATNGAAGAACTGAAAGAACACCAAGCCGCCTGAT
+
'"#$+"'"#)")$*(***!+%%##"$&'"!!$%"#%*$')")('!!$#")%
@r3928
TAGCAGCGANGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCC
+
5-1?25A,ACC7B,B&/<@&=5@+4.$,!G/9F"<7,<=(1+3$.1CD:6G/
@r3929
GCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCA
+
*G+(&HC5@,C52&*H/&(H'!-51G-#$9%/*8$&B<G&1'E/,..A28!!6%#1F*3+*+*=6!3;(<*3C80E:F2CC<D
@r3930
NTNNCGTNCGTCTNNGCTNNNNANGNNATCGGANNGAGNNANACGNNNNANCCNGGNNNNNAAGNCNTAANTGCANTCNNANCNNGNNN
+
$#$"#"$"##"$!#!$$"$""$!$$!$""$$#!#!$#""""$""$###!#!!$$#"#!!#!#""#""#!"!"$!##!!"!$""#!$"$$
@r3931
TCATGCCGGTCTGCACTTCCNGCTCTGCAATATATTTTTT
+
>-5).*#.FA.DA6A%D.(=0G26<(08/!-EC)F9$41F
@r3932
GGCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCNCAACATTGATAACGCCCAATCTTTTTGCTCA
+
"%9G8*ED$0<!:.>5<-'G4>.<4$>:8*59D7230@31-:$B4D<G/*<=0B/<),H$+&48H3A:?-+B1F#H>;<8!+3CBB0C%B$G58C+=;!>2D>-<70C)7(F('H9?7/3BC9FFBF$F!G=H/4/()3,G,9;=;9+
@r3933
AACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATATCCCCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGG
+
(4%3B6-6<F(+>8#:=!%+.FC?)F;>44>=!3-2#AC?5A?CA36;B'92G'GD(#"CE',8H@80B:#GHF+<4/&34%3E"!C=9-G&@FA19-
@r3934
ATTTGACCAGAGAACAAGAATAACCCGGCCTNAGCGCCGNGTTTTCTTNGCCTCACGATCGCCCCCAAAACACATAACCANTTGTATTTATTGAAAAATAAATAGATACAACTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACA
+
-E,0!6?+9=B.9<B+'=85)@&;B!991(<,D,%#1$?%'@,AE@&#%?23"B<)99-C'8*-68D7D#2*815=6--:35&A("F=A<*HEH;42@,>(*1$C$4B19AF)!7!0)<60ED*8).1$+7(1=5H30;DEGA$(3FA2:16&>58/;4$#&-:$1:4;">+,'06HG&')<:@C,:'>
@r3935
NTANGAAAACCCACGTTGAGNNGACTATTCGTGATATTCCGTCGCTGCGGGCGCT
+
(*%")*+!$!'+*)!"#'$(&+(''"%)&)&)!+%+*#!#'"&$&%()))%$(&%
@r3936
CCTNACCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTNGATTGGCATCAGA
+
#$&$!+(('%!+&$'+&*#$'")%)+"+()+%"!)(%!)*!%")(#')#'$*(!"!(!&)%)'(("$*")
@r3937
CAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTNGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGANGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGAC
+
;A0/A/#4<"B9E61;$G)/:/H+16+*-0'=(B<G+<69D9#26/!(8:,E2&4.0,E+#47F0%2>C>"!@'02C7%@2G2"8B@G--/@)F?0%#"-04CA*?-&G<"&E6"$/;#>DF'>4-GGF7@)+;G$GG3&.-46<7#>'D1@$6")C;E5"@69D=>)G
@r3938
AAAACGCCCTTCGCAGCATTGNCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACC
+
.D,C8&&72:#E0)9G)B0=.GCCG)%B6A-)C*%59?4>F1B?&0E'&-9<03(+2%5D61)<0G.1.!21;&8:'(A%H/B;A,1/F$/@2<@@!H)'(D51329%/.E2:+?30C;1!""C8:B*B:@+&/0>G3$48.F=0)
@r3939
CGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGNGCCCTGAA
+
;$8C00B!7+>;>+7%@A"D,?8@HD*@F.E;?>A,,A>3B83)GCE>1*2B?13+"D1#>HG(*/?<)%93<F(3A91B=B/E'6;@3
@r3940
TTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACG
+
(<6<H:&3BC+3.C2,09<)%%F,G;F-3*0?-.-A(7%1409&?G)A9C"-3/*$.
@r3941
CGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGT
+
.6*@9@:;=717DE'8-!09#24#5H?!?>#+>%:2<2(-3;GD!E1:>B
@r3942
AGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGNCATNAAAGGTCTTGAGCNGGCCGTTGAAAACCTCAGCCGTATCAGCANAACGGCGGTGCCTGGTGCCNCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCCTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCTGGCTGAA
+
::<.7)/40.-H<)856,7(?,/5E$)/.-7'<5'.*FB(#<+3?G"D#-;F@.$<"C'CA1)<F.0'D*5+#5(,(#570$+E*,@CFCC?8&=%*A"1!"(:5-93#=84&.A8<"?3+&G#->-!B$27/GC<4/":<'A!>"3',HE.98FAC8(7C1G/?G075"E(#!9FC(E>3B;5.C0'B#$0?!E0'7!%5%=3;;9%1A$310F$2.9*2.$H&0A4/-60FBH,(@!GA>1)#CD;077#/>03/B$4?D*<)061.:=/6!>4#ABED
@r3943
NNGCACTGAAAGACGGGAAAATCNTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGA
+
#$+!&'"*'$"$*&"+%%!+*+)**$*&&*&)"#)*%+!(+)!$*)(%!$"('$*!!#*)!+&'+&!+)#*!%$+#!"$"$'$%
@r3944
NTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCNATGAAGGTTTATAAGTCTAATGAANACAAATCCCCATTCTGCAACGTGCGAGAAATGACTGATACCGTGCGAAATTNTTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCT
+
'5F;,4)A.189"80.3745%'1*7=$'?,17"D#$=/D?E-::4+A1EB4G2,:$HA".&>B#B0%E(*!3//!:'2E6&B8;(5#804/;+.F7$.?3A!AC='EAG8A"(/'D=794>"B#A$8-0$*B9!@=..E--1:973:#&&*A9!99*D4)6"F@@
@r3945
NNCTCTAAGAATNGAGANTGCGTTGCTTAACAACATCGCAATGCTTGGANCTGNGAAGACAGCGGAAGCTGCGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACG
+
#'''*&)!%)%*)&*&'"'(")+(*&#)%&'(#!!*!+'%!!&!+!'#!(&""!+''*$')+%&&$)"'$%)$+!%*)$!"%!"%&'$!#")")%!+()+)$("!!(%"*)!#$&&%(+'"*'!+')##"(%&$*+'$"'#)!"!+('(%"%!&%#)!!*"+!$&*)
@r3946
GCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCC
+
8D0@*0*?6C:2.1*')E6C)D&/1>-0G#(.@'B6!/$<4+3%*=67$!3$"7CGH8,<E5?.H8*=+2!2;C?.C&"2%0.8
@r3947
TTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGC
+
>(>/"1-"C2#8#A!H2G2*;('!+6(-3F%&"!0)3=.CH!)
@r3948
AGAACGCTCGNTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATT
+
'C6,1CH8@#":6!F5BD):=>FA,18D7+5!=<5//D8=):B/%70*.F*)/@'!&=4;#A:?6C7"1)8B)%@:;:>D5#/(5*<8@#825-C
@r3949
GCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCCGGA
+
F,A#0,/65@&E=GC3<)>>52>:A$+A4H7?0,;56:&(.
@r3950
NNAGNTGCNTGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTG
+
$("*%)&""&+*%#%!#%!!'"'#'&$('$$*&!"(!&'!"$!+'%+!#*'+
@r3951
GGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATGGGAGTNAG
+
>#5&A</>-?4C&"E2&E@(FF*%@?7"/%9>.8<==:1-:(9@/6H:>'$6G#"H7,'G1$,06=/7D'#(H@1%H8!39<#,:!8"-/F@CB56018'?(&&@06@CB,/(;5(/":E9(A#G>26>10A>E"*A3<;):@4GB>1H=+88D3C2E6A!2B
@r3952
NCTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGGTACAGGTCACTAA
+
'2<;@CD.G#FFC3H8-HC'0#?;+%H5--=3%:=H0%+E-=CEFH42=,C,!(;.*$5+;1$-?5C/&/05,;,:1@&F'%07&G@(2<E"#G1#<:G;:)*#9AF:5A"
@r3953
GGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAA
+
E"7-B*.$,B:A!%-26C8"&2,?C#+8)C&.?=A.!//0@%2A>)C&1E$&;D>,8A88;3#70+1(@B':'HB@$367*
@r3954
CATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCTTCCTCAGTTGATGCTGCAGCGCATAG
+
8=EH*:&5'5&:2$?50='=@0"6FH=998&,,@C.2;?/E4*D<7)HF?6!>B0#::$>1,000>9A?@!'@H&D
@r3955
NGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAA
+
!7?*><03A*;8G0:$7C=+63<?42A02(00?<-;18A##+3
@r3956
AGCCAGTCTCGCTTCGNCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTC
+
H</<G9::!!&D(H8,/=A+A;6;#3$0AE$<3,%$8C3H=H4(*E!)B;=<H3;G34>9*"'&6?A,,ED6
@r3957
AGAGTCACCGCGATTATCTCCGNTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGC
+
F&G::#">,&-?5)#F"%F(G:;8<17<50C@')C1<:8251@5,G(8*3'=$&-A9$)
@r3958
CGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGANACGC
+
;C<9?;19;#;>49B6>=@$?!$(2<5F=C6&EA&5&'F'**>7"3%&%@..E%.H8:(%(!1
@r3959
NGANGNTATAACGNGTGTNTTAGNTGTNTCCATNGCTACCGGCTCGATTGATTCGCTTT
+
'%"*!&$%*&')*")'%)"''#!(!&$"("'**($"&))&'+""$#%$%)+"%()""+$
@r3960
NTGACTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTG
+
#'*"+++*""$'#'$*+#'&(%!!+(!!'&(%+)())**!*
@r3961
TACTGATGTGATGGCTGCGATGGGGATGCCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGAC
+
F1%2F8'9+8:<<6=((2#1-;@D=06B+C49<D72G-%,4(03A2(/%8G>G3<?%4A3,0-9%D3A2D?7*FD>BA!<1;//&D:C(4/(<A
@r3962
TTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTANCACCTCTAAA
+
;"$A*$;7#C;A>B*G,/-DB2-+A8$13A8@9:B!%3$BBC:B*(0B1(HD6&#66D=B./@
@r3963
AGAAAANCNGCGCANAGGCGGGTTCAAGCATCANCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCNGCTGTCACTCTTCGCCTCCTCTGTTG
+
D'2!CB-H8**?%=17C&'+-./"*"(+78,7BA9H7A;9-9/3G6/?B0B=";5<>BEE5+&*)B-9E77'@,)%=9"4HD43<%@-5"(7*:D3+$8-,3=H8#2*1
@r3964
TCTNNNGGGNTTCCCCTCATCAGTGNCTCTATCTGAACGCGCTCTCCACTGCTTAATTACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTG
+
##*!!"*$)!++&!($%"#(&$($%*+%##**&%%$+$**#!*+%*%&%("!#!+#"$%))*"'')$'"$'!*)"$%#!#+"&"$)'"&'!$!*+%$++
@r3965
AAAGAGGAGCTTGANGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAA
+
3E1ABG?C.B>&(>=EE(,7""/*=&=9DA9A/D5<H/05341=$>G((.>@41=-1,'0H6
@r3966
GCNCTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTAGAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCNTATAACTTTTACGAAAGAGTTTCTTTGAGTAATAACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAACAGCTTGAAATGATGAAGAGCTCTGTG
+
E!32$/'(H8"&=-:,6?5B!C<;?>,',!D5;35*@A:3*E5&/+6+380:@E"9,6*C5=6;H$1(6F&B&H65()<9#-;,A:1ED!5G,2&?'132)/5!B!,9;77)E$2H)'+$F<G8'.-E.$!6-/#H:5C:4-/D+*?'>5>!.>+GB4!92232C8H,5?E0*G%5+,,3*7$?-082"9B)/"()";,AA$#7")'#H#+-'-$':..8H&(#0.$E)'.%3<.;6
@r3967
CTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTNTCCATCGATTTTATGAATATACAAATNATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATNTTCTGAGGGGANTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGNCTCTTCAGGCCACTNACTAGCGATAACTTTCCCCA
+
661$F8>'A2>*4(7D,58">+@F?$'H,:;52'<E2(065"C%D$/;&C<E688C-6:E*<+<%/,"+9G'>&;<4785#>;A=%,3!.D+#2-275),?2C?=?>.&"G#,9-<5)B+*F<D(&FH&8><3/>G!<B(EHG3D0&'0A<&+#B(B2%&")'"::%>%1<=%=89!>45/9FA=3523B#!&.+9A,5)-#D08*(2#->'%,D.)A3$AFE=B&=-4.'@F24$--5.H-=:%$AC&%;*)3(640'B=G2>#@B?!2&#,GD%03.);$>45*/'A%&5'<@D7C!4"H%,5+E:&!EB:G'<2?/)A=?HA*0#7B1E;-76.CE323D="3GF0E'FA23;$>.0/,%-*$$4FG'3,#?/(()@8"&&B(!D>31-5".?
@r3968
GGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTT
+
H)<G">C$*2"4>6B#+G32)=-(3?<F&C!DEAE>3$8GA9:$/51&&*%D%26"
@r3969
TAGAANGGATCGCAGGAGGAGTCCGGTATCGCTGAACCGGTAGGCGATCTGGTCGT
+
#(C3?C%,$0-7C?@&EB$4+(!1")D0-5#')+<9"C5C-6&E-CFD@'&1&2=$
@r3970
CACCGANTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTG
+
'1-)F3-*=G,"<A*=?>HA,=.FA/#7%"G5$E2<G;2=H+&(
@r3971
AACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACT
+
4<B$E3H''.,$=5:')50<$&'072*3!/7/@C0>9C5@=72(DA5/:HD>"0,F!%):0*8%9+05?=A66,
@r3972
NGAGACACTGCAGTCCCGGATNGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCANGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCACAGGATGGCGAATGACCAAAG
+
%H(085G4&?GC2!!)+1%+&3(&2.)7E;0%'"30/B,.HF1?*65?GA&6&5-:*D=/)6G*2"&1=(/)=)6(H10*3H:6,;:09$2H5:';D&=F(.A4?!!EAH>2'&%@:;;BB3$+D:;.2(5-H;@C>3+A.<)2&2>CH?$?!GGD(0#9$CB"G(!!B6%A8H#'G14$;=!<G13?HF6C,6A(9"<=:EB95!8+/3%"53*G-H'"*9<H%4)"C8A&H(?,9%3
@r3973
CAATAAACACGGCTCAGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGC
+
'CA:7>>:%A#H#H;,,H7E/CF34)>*>4GH%%2><@/+1=>/(9D=,2B,<6H(/F(>>+&DC86E-D&:7*3D
@r3974
TCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTA
+
F,,&5'3<DB=%5,0)=G<?+(H>-)3%1$)H;'#-1)@G7-=?-&*9F'E9HD5=+B,-",%)%(&0'G5.'>-/F<&@FB;."<7@7C)?!:C?6?+,#A.)=G6*5!=4#"C-;9H=7-!-,32&$3+6;3:,G;:.'=>HE&(/4=,7G@:/E!7E*4D)277
@r3975
TAATAACAGGCCTGCTGGTAANCGCAGGTCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTT
+
;.0&,@"ED%$=7.92:FD@!5CACA;$%.H$#8FA'B6F&.%%"!E%$/+!++B.3#7/#.)@+$HE8D=4
@r3976
GTTTGATCGGCTGTTTCTGCGTCTGTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACAA
+
D:<!#6%B*'DG>B&%;>'<30#<%$:>#'6AF.%:#B51"#8$8#22%)$/'-;"*<*G+.>!E<)9/,36""5/
@r3977
ANCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACNTATCACAACGTGCGTGGCGGCCATCAAACCACGTCAAATAATCAATNATGACGCAGGTATCGTATTAATTGATCTGCNTCAACTTAACGTAAAAACAACTTCAGACANTACAAATCAGCGACACTGAATACGGGGCAACCTC
+
?G(BG**(3#E=9105H/380GECE"8'/2(H3HC29CG,%::-&*:-3?;18?52?#0@2/>4'@:5A$E7>>!69@8:BB.>1F;)*@347HB0G9HE1+B.?(,&G1:25'C8F/<1<G5:-*=BB/8#D)54#AA;,+*0#F66.+!0*9FF@@0,ABA!?6%(;;H0#8F83#?)$:1+)D
@r3978
TTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTG
+
B8<+*B+"%D4D+!;9H0@$,!B%5A!&":%$/*-.347A$*-229<9!5A<2/'D"<$E#+9-="$-->$@3+HH2;7<FE3*B9>86!FEH7"8@2??5CE?-@"$-G"!.4901>.="D4%#4,7=A02:4:.#$%B+F--?G"<?5E5AD<;=:55#!:6A/!F(0(H=EB6A,'.7:E!8@<1D+.@B3&/%9!5$6.-%/3<1&F*+6)$H?=9G(+?'2G?=CC1,.2+<2=5@6$8:1+@F<--%"FC;B
@r3979
TTTGAACAGTNAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTTAACAAACCCTAAACAATNAGTTGCAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTANTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGG
+
8$1H!A'+57#>4"C=39A-EE!$'2().6.%(40,$?E<=C:'8E4C./3:'><-2G/'H5.>HA#5!$#76@D/2'<63!A=/?87%6.#A=H)"8A"%*A<@-BD*<!#"E,3:D"(-5629&A0=17+F?@>FA0D:3%B?@63&FA11B47)!)D?4>@B++%&>B*36=E=.6H==#:6$6#H>%F/?5'><F)@GF7*:?F&7.F.)7;1//%81?(=+-8,>@85C$E&#%*;>%FHE>B3/H.GF83C+4#:@/28;#@2
@r3980
NCATCTTTGCAGGCAAGTCCGACTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTANCGAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTA
+
$7."25>6'"1'-;)G8,AF%6?)240<0.3!<4B?)>F7;306F343H>B91.'50>=/8=E3:/>F.1D:EB23)"4D%6B(-G,-%,>)E600,#A=1#="=E+14+9CD9702B42(9EG;A6(GH,9+6()?9EG>E<GA0CEGC:'8EG%**3>2=+"#H4C<C<E#4,
@r3981
CGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAA
+
"H<507+G,*8#H0/794HA(*;+1C4F!0/.&"27H(&#C$.C
@r3982
TTNANCCGNNNGCAACAANTCNANGNTNCANNAANNGNGGNANCTTTTNNNNNTTGNNCNCCNATNAACNCANNATNTCTANGNTNCGTCNTNNNGNANNAGNAGNNTNANGACNCNATTNTNGC
+
$#!"!#"#"!!$$##"#$#"#$!!#$""$$$!"$!!$!$"###$$!#!!"#!!"$"!!$!$#$$"#"$"$!$"!"#"!#"!$#!$!#"!##$"$$"##!$"""$!!!#!#$$$!!!!"#$"!$!#
@r3983
TNAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGA
+
$$-<F=$GE1+<,@920C<1+,:H0::#&>B/1@0=F=C,C"6?85>F"H(:-/H@?%94
@r3984
TNANGANGGTCGTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCAT
+
("*$'"!&''*!#+&#+!!!&&&$"'!#($'%"'(#!&#!&*#)*+$)'*$)+)+!
@r3985
CCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCT
+
&45A76'1'7C4)D0"=F&5>;.+")#+8:9-,451D''C'A/H5E>C)2?4'@?63BH5+21:C?(!$A0=-1?#7<
@r3986
CTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTG
+
4D0G"0?=!<(.79*.43E'.041:!($/5"1D+CBE>=D0.$,(,(.H:
@r3987
AANGNTNGNNGTTTCNNCCCNNNNNNNNCTCNCCGGANNNNATTTNCANNNANACNCNGNCNCNNNCGCCCNNTTGGCTCNANANNNANGNCTNCGNNNNGNTNNNNNNTCNNAGTNTNAGNNNNNANAGGANGTCNGTANCGNTNNAANTTNAGTTNNNNTGNNNNNCNNGGCNNGNNATCATNCCTNNCNGGATTNANTTNCTGCCGCCGNANNGGNGGNNNCGNNACNANCGGNNGCNGNTNGCGTANTNNCTNGNGANCNNGCTTCTGCCNCATTTGANGCCNTTNNANNTCGNNNAANNGTA
+
!$!$$!!#!"#"""#!#$$!"$#!!"!!#"$"!"!""!!$!$#!"!"$"!$#$""!#"#!"!!!"!#$##!#$!#$"#$"!$$!""!!$#"###!!!"$"$$!"!!"#####"#$$$$!!"#!"!"!"#$!#!!"$#$$!#$#"####!!##!###$!!!###!!"!"!"!"!$!!!$##$"!#!#!$!!$#"!"""##"#!"""#"$#$##$!!#$$#$#!!$#"#$$!"##$#$!!!"#""""##$"""$"!!!"!!#$#$!""!$$$$$$"#"""$$#$!$$$"!$!!#!$##$#!#"!!$##$
@r3988
GTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATG
+
.!:4+8C=<4A$>$:!4'/,$;$BCF'<;-"6A6=7G:0,>)1'/(#D3!%;#A$E0>),
@r3989
NCGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTTTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGG
+
(,#(@-G!*')2A60&9#CD*40'@!,1F<9+7*,G;->9,%9'9,6239"E?FF.-03:-/>FA*9%,EH4?(1H')%1D0F=;B27+&@37B'6'#(+:-:0%0(,="!&D$B'!!9?)F1:H!C/H#G+28<!=%<G!#HC2E1.5>;:%(,G3:#AA;0()/E**CA<H9/.>E81?3GD#&:*$#39-<?9""GG?7926".97H9E72:$E!:59FC5@*&8,2/<!AD$G,.'4*EF+@-H#'FA;;.@=3%>E")H%B?C9,$1.>GE
@r3990
CTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAANCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGNATGTACTAAGGAG
+
BB<953D0.6);)2&*F<7'#B"%9=?!HG><,9D;ED7A?H+?BEB8BB2"*1"+75E;@HH9,'>D7B*/D51=B4(.7=;<?+*9+?78!?C-C)?E3-2BA79A$33#>5+*.!(ED#@)E"7B<5$'?37?GA!@:'(#%E!;CB<B&C8#"(6-1@$!?;-0;8:>(
@r3991
NGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCNTTTGCAACGCCACGGGGCCAGCAAAAAACCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAATCTGGNTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCCGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCANGGACCGTAATCANCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCNGTCGCATCCCAAACGGATGTAACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACANGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCT
+
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
@r3992
GTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGCGAGTTAAT
+
H2E'<D<&7!&?9G<<%6=*6=6.&:$8<2:&%<+1@-<"?G,=-DDF!.8AC).C**#1H-=,-EC<$FF1%C20#),'CH9HF-@6='G(E/8).AB5:C-?"5%G,=>!9(-+*C*+B:H4==*''C;().=@(=@*A
@r3993
AACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAAC
+
8C8/$F-D@#:A6:(3G<'-6CA-!-0/"4:B!895=<"?"":E3&)FC%#%"2CG@-,;"A27E'C4>4&/=<)G(;A2$>E*E#=>-186:8'8>D
@r3994
TTCTGGTGCCTNGGGGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAG
+
3?4C>,:93F$"G(",)B,HC?1#-A78=E/(>7DF,A):<61'D).!-/HGG+77.@9-EF6B2;2&@>)8(BH(FE!.?@'&;?;!>C05/03HH0,1G0F=#&8%D'4274C@/<4#F3&%.0$(G@;GH;##:*4#DF
@r3995
AAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGC
+
AE2+%;0A(A6H86.*F9A/-="*>:<.@;>8!;92@B60:@<B*5'D6-(FC*D8<'-;B8/$>19#(62(84=D5"$51%1&A:B
@r3996
AGGATGACGTAATGCTGATGCCAGTATCAGAAGGGATCGCAGGAGGAGTC
+
(+*'&$*#$%&!)'+()$*&$"&(!!&*+'))#((!"%!%)*%'+*&+!*
@r3997
ATATAANAAACATACAGATAACCATCTGCGGTNATAAATTCTCTCTGGCGNTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCATTGACCA
+
*$(()**+%$(&*(!$)&%(#&"(''%$+#%&""($)+))$&!))#"*&"&'%*&(%"+$)$$%)'#!+)$""%**""$)%+#*%('++)#&&'!#*$%()"!&*&%"#
@r3998
AATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAATATCGGGTGTTGNTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTC
+
G(E)=7+!9:@HF,G&E7!FB.(H,@G*+)=CG;>>)$67=0$+$C+&*!2/&"6-=(E)$-78!=C?%:;--#3>,*(-6E/00@>(<1>9<-.";H7=!D&C;B&31
@r3999
GTATNGAAAGAGCGTCCANAATCCTNCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAG
+
)&*'!(%(!&"**++&'&%"*((!+!)%!()'!%"*(%)'#!!%($"+(&#*'((!+"!%%#'%!&%"(*#'"&%(#$($"*''&"*$)+%%($%))"*#%)#
@r4000
TAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTNATCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATNGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGT
+
+05;8C%8F622DC1<.><-:%;5C0=;C?#"?.?0$-"B!2&7E63.;"+0%,#F&4.+5A6@=C(G!()8?>39/:>*D"75")7:=BCHH=+(861$)&-5"8A8:7*85/;6&8+,F27-7'>(86)<>A7F)&&)3E%.G.(&;9$)'#F#-5/-(:"B9;:H.))
@r4001
TGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTNAACCGTGTTGATACATCAACTGCACCAGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGC
+
-H-2#(3'C-;9=-9G4'C"E>H!.F/=()#1:6'BE)5+<6#/1/C78(151,/-&*!/(E8;$'A3B6BC/#":(906(827D!'89;D$(A>+C)?&*./7/.6<1(A)E&-H6#!?#+<@<FE@!@8581FEHH:18<C!G+A5,6H2!3?'$6@:326-7'+H&**30<<.1C$7-<!)DB),>#-6/E%@2B9<?'#+:-5<G#$$!#"9C,5.66+BB'9+3"!:<:-;H08(0@E$+:..)@D&&83ED4)952.;D2=-2@-+4.2+,'7H2>1<7)0;@G.#A>D#,:(=4,B<@">
@r4002
GCACGCCTTTAACGGCGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCAGAACAATACCGGCGACAGCCGGNACTGCCGTGCCGGTGTGCAGATTA
+
61$%#6428<2<'H'0G+8C05A("43,14E-<@4,83A+'77G)!:+.5'"6!,BE0$BA,(-"=G5-(-)F76A<#=ED>E((65C?$>'(E+53.?C6A&B8*+<,.EAA$'"G,>AD>"!=D6ED?(**8*(DA-F03*,:?$)8&7681)
@r4003
CCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGNAATCAATCATCAT
+
;?A4$*6H+*7%='BH9<:,-A/-G+0>)#E5A*32*@=HB-4A;23:&67#DD,$:$0!-@
@r4004
GCTGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGC
+
*%#+'#+)##&))%)+&#)')&!+'&$%$(*++$('"$)!!'**)*"""&$#*)#$*&(&%&$&+&*!*$$$$*++(*)*&*%&!('#"*!*%#'#%"+"*$!#'
@r4005
CATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCAC
+
)A&)"-HF*D=-ED+6>*9G#'%)-<4.8DF"6(CG(.=)*--#F>(4<,():C&&99D-598":%)8(G8&183##)(;C#;
@r4006
CCAGTCATCCTCACGATGAAAGTCCGGCATTTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAG
+
-=-@1.#F>/D$=:'!0?<89%-4+**F/+&A.C8.)&E%31$=%-=?'2?)F$AE:B@)2+><*-";6)1".A:C
@r4007
TCNACGTTTTTATCCGGAAACTGCTGTCGGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCGGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATC
+
3(EAF27,?C&25&*0"@H,8:8?)<=($3%9?A'(9)2()>++CC#9@.?>>A;:C27C>F)5!F-$%G$#F?H'>2+>B?85&:0#4$<!082-3/88</CB>0G%H>>>(0?<>&<<=+4B"&&E<,%<"7$>$*DD7"94*,?72(76)0>;B/>B8E/7?@"3@?!F(B-C#(.#>,7>4"B&/,5>54G$
@r4008
TCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTNGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGA
+
C0##6B@43#677?4*$!:35?,)?'132$1%G@@?&8"2=*DE/5&@24E64+)FD<:,7:?A&7#"!%3%G<00.!-2+*E*BF#D1.!2=E8@27$<!'.2E3-%E'+:@<2GC%6'G*G!@/34:-F<&4/1H(>-(/4<,06@1)='BC&?<EA+G'E):=A&8A;?D:3C@8?$.C-!!#;6<$0*:$649.&0(96;F+"EDB9!:*5F@6()5C.:/9G>DF!%
@r4009
NAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGT
+
/>0<"8H<8,<H64&$,,!0/?(5H'1D%6#=&C-,G'**9F9,*:&?>#)6;B36B:'//'#5EA6(
@r4010
AGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCNCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTTAAAAAGCCGGAGTAGAAGATGGT
+
'*>?BH)(C42CC"63$32&A:(A$00&,:*EB'@<(+C=)H);)B&FBF8'*+2584/<6"1ACC:;F!'C;"#<F9CA#1296/7D0'"+8)-2(A9)<14087@0*<",+2=&F56=7#+C+E*"#+/H<&,%?2&?("F@)</E:.:.'E!E-3B777G!+F@1$,7ED*5/*828+0F!.=#)!38.7:@;2-2C<"HGA23)D5#BG%2'A,?+@.>674<<:@CD/@<35231##D0A&,/G.5=F9@;C@DBE-0:&>1,C2@,1>:EA5751A-#3F/)72)3@,-&'89$(&?4%C%"%!(;"A"3B=9'),&?"=6+D@BB'5!E)A/3D<1>8@EEG?";E@H,EC$'+#0.=F-1$<+*5430:/82'-C6(E(9$*
@r4011
TAGAAAAAAATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCTTTGTTACGATGTTTTATCTTACTGTCTTTGATGA
+
%,H*0(%35A5<D##2%>E+-D"+7F5B4D92.,,&1;-!/%1/==C(.4#/C!;>9F:=B(21:0?D"6/''"G?;5#@(3//3
@r4012
TCCGCTCAATATTTTGTTTAAACGCCNTGGTACAGCGGCACCGCCATCGGGATTTTCACCACAACAATGGGGTAACGGTTTTTCCCAGCCACACGCTGNATGACATGCCACCGGCCATTTTTCAGTTGCTGA
+
',E4(5;?+G%+<&GD/+EG,BF@6E#>891+@,!);8)AG7@9)!=F-<*&,@G$'4.H+?(-3"8-&*"$67E@#;</4F022;%*:*A'&FF>(->9B>7/5,0#$1#)21D*081.C3-;5;/H.0-C
@r4013
GGGTNTGTTNTTATATGGCCTTCAGCNNTTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCNGGCAGACCCCTCCTTATTGCTNTAATTTTGCTCTGTAATTT
+
#D)<6<>>187$;-".)E2%>(E98CE:219>",>F?%3D.3E,C'B4+/=?6+=&@'88#:#2'&=8DE+-;"=">F$?(&AC%>;2/G86GD3<4#9G5-6;B'!C0*)-@<GC<8'?860./8%F2.;H'H=$D%*-H!E%;73.;7CD--5075!C./,2&0%-A:%)*3152$0C*2F=#F4=,+28/+5&H
@r4014
TNNNCTTANAATANNGTGTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAA
+
*"!(%'&#&("'&$"&+%*!!(&"$''"'+"&)%(%&%*&""!!)'$(#)#&%!&*())'!(%%!+!(&('(#&'!**+"*!++!"##*#&'&"&"
@r4015
ATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAAT
+
>BH,<F".;-08+?@/%!>**%A*+$?A+8&%0166**,A9571=)3D&*@:,=!?$9+,35A47EHA@1,1FC'*--;A8H34.?+<2GG2A
@r4016
CGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCA
+
/8F8F6+CD/*<$2?5-.G'G$3&8;H:D&G;')<=400#
@r4017
CACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACG
+
<H%!9E9B/GB/"#"F2:4#?G;)"4"!;DC7;.E%%A,H0:8C,1EE4
@r4018
CNGATAANCGTCCTNTTGANNGCCAGATANTGGTGCNCCNGN
+
&$*'!"&!&&)$)&!%*(&#!(%%)##)%!&&#'#(")$&%!
@r4019
ATGGCTTCNGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCA
+
G'C#%(G>7),5!.E.F&30*C()@03E77$2#H/E+,!5FE,AB-?(1?ED&F-!G4,;F3*HD7(*A.?
@r4020
CTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGAATCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGAC
+
;=174!1/G2056?6&"@&#)2;G94<9+>2$32.5&.-95$D<,":$=:,H0"*!),*3D1?*<H.58!@.D5>/C<$;H23B>++1,!B!E)!8BB@B*+F1$$/8+B6'/2@98D!@5B2?G,0!;&+@.C)7!450H0FB0F%/'>*&>HF&>-5E>@*>8)HF<%'9H<A>=&
@r4021
GTGTCCTGACCGGCAGTTTCATCCGTNTCATCAAGCTCCTCNTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATNACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGT
+
,<6'"+!:A6;-!C>3.D!7<>1C!'+H7E,0=0@#$3E@F2H.:)::G*;):'5>6)9(F1?=('HC*/+$'.EFCAA<@?F2.G*=#)'+-&%60A$0H(:"?=&573#6B-8"?3H%9#,"7C!FFC195(%:5$2>:E(3=H%"A>0?#C;GA+$9D9.&29A'2)D#2C@2F&"BBC+17%$!7.1>+3(AD26+E)>=*(-1HH%=99HA2>:2C!)1/9C<8G)7>D:B!<C%'GCH/7$C1#&
@r4022
CACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGAAAGGGCAGNGTTTCCC
+
9F##/3"D*7$"3<3C(H<(4$=*%62=%!#/".G4$68H$9,)%0@0;(=0-!A$(1<(D/:A5
@r4023
GCGGANTCCTGTTNGNNCTGNTNTCCAGGGNGCCCATGNTCTCTTTCAGGCGGCGGGT
+
!&'!$"*%(*)*"!)"#%!**$#'*$&*'$&*&'$!&)"+*%*'#'*!)'%%&!#!)(
@r4024
AAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCAC
+
A2&0*--,/&(:*A6/F!E0@@.C;)30",H%A==D&F*:?G9=D
@r4025
GCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTNGGCATACCATTTTATGACGNCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATT
+
#07?B4?8013'+51@'A9'H,-&C?9#;?9);"!G:=B50$-"?06%/'9/><,>.?0BDF/8H'>2G=<@**1=,D==:+B%8.=$G7,5B"<7/5%/(+9,0082,H4&B75=$%9"#"G#*>DB7+"+"1)E
@r4026
GATNAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGCACTGTCAGACTTTGAGAAGGAAGATATCC
+
B"-5B6F&%?@:C3&-D*<32,@?);8@$;DCE1"+5D8<1E."0!2:6>/A+71H,6:5$"1;*/'#.@%G+&F1?.'
@r4027
CTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACG
+
?HB<6#*&4F*D9H-22#":*'1&:"=@59F/0/E,4/)$#C@H0BG'-"F'<766F?DC@/D<%!(G>=H)&=+'
@r4028
TGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGT
+
6%8:HFH-==!+;"23-G4-6A./.D)1(B()3/C%H'!"30EB-F@1>;G/5-%8+",066%7;1@/5:)$&/G@(2H>B3@C38BA:->,A#(A,5G6%/'#;"99)'/*1-C#-;,'@8:/4B$>#D6!H9E,G&G(7#/.20/4DH&9%0%5">"#.(.4A#$",/!%4*!,6A2)(G$E5-<G+;5)65B@+!BG1F5;;72G"3*,F?"B(A/D&6:D6%<EE<E4;>$,1&=*/+5916G;.<*A##=A77*@
@r4029
AAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATA
+
9%8#)13%94*3!D0!7=,!<:AD&5D)<F6.'<$B@CHE6C+<)(",>9#!6-09&:==0@-7#1)+G,4)F>*$72$&E<'FB6.D"B@04:9
@r4030
CCCATGACAGGCAGACGATGATGCTGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGGCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCNCCACGATCAATCATAG
+
0-.@;2F$H0<.;'<."5+4H-#>!71&513&"@%"D3!!),6:,,><(!)7!#,)&G$BG1B45@>!,6&@4=F.2-&#&$CF.52+GH-&777EGFC=;1%8&H+06,#4?/1,CHB=7762804284B.F2!,0%89'44:2$&!D)""65H+5#>7B5$)>17E*5)?"(;#;-5&//,B&>5,=?:<*(>DBC-1<%37EB0F?-B;+.)*)#4=F
@r4031
CTCAACCGGATCGAAGGCTTCACNGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCNACCTGAGCAATGGCCAGCTCTTCGTCA
+
7/G=A=4&&F;6=F%G,"6&>:,.)/!C35&&B?,5(2&&&!278=#86(D9@7#)&;6H2F9;;)+.H=0&/0!F25?08EB6/+?B<?GC$<(86/"'3+3
@r4032
CCGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCNGTTGGTTGGGG
+
C-:0:%&GF)-'62.>1A)&!*$!;</.(BB28*0&&&B$7*./',!@+$B!F;%-E=(*(,8&7
@r4033
GCANTTTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGANGATATTAAAGAGCGTCNA
+
'*&'#)+&+&+$!'!$&"'&%)$("*'!()!+'&$$&$'++&(%'"$'#&$%(('+&+')'&!*(%"
@r4034
GCGATCCGGCGTCGGTATNGTTCCGGATTGCCGCACCGGCAACACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCG
+
A>59<E8#:9?D"G"->$57%&;"#/"+F>H48(,4*!(#D#A'B,&4+,;E;8D/@=F-?40'>7:;3483B/,+)*!2%&!F2)--,$?,5$4
@r4035
ACGGATTGCCGGGCGGGAAGNCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTG
+
16!@G6#G6'-;@@$0'0))?7'E'->+3E/19%C,*D6GE.4>+E68$=8$;8)F15>0)8:?"C8.F)9AB-.#8#<'(1-6CD<AE<<&H62;!DCBH$&EF+9:BH5HG=>%)5?/=8;EE9?)?:&
@r4036
NGAGCGGGATGAAAAGTACATGGCGAGNTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATTGCGATGACGCATCCTCACGATAATATCCGGGTAGGCG
+
#28C/>G,8?6(<>5!@GB,96/-A;"9*0<%.43A"5D#:88G.3=,H)/7EB69E664)@>+0F,<(8A5,=EB.0FDE(H?'"GE8!."@HB?1!<HD'B$11$:>D%GGD=:$"B+/61=(*0"/&H"F%+(*%:41&;5)
@r4037
TGCTGATGATCAACTGGCTTTCCAAACTGGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAANATAT
+
:0+?208H$7A;B*3*6:%1:-&E2"2)@6=9$*5=6,$#=D/=8FC!B'F%/2G*><"+H9@(-3:;/
@r4038
CGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCG
+
7.;)8?!G,/,E4''&5%6!"*8=C<#@FD+D#"E,A?%,1=BF5A.!5@71B9/E.4D%3$8(%:=+83,2;83".>5D15;!'$:%4
@r4039
GCAGAAGCGGCATCAGCAAAGGCCNCTGAAGCGGAAAAAAGTGCCGC
+
E!0-F//,H5D&0%3G0,+"/3$+G7<&"=/G1G:.G"4='F)F2#$
@r4040
AACCGGAAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCA
+
F)&A,?B";840+.@:7-&6!H?#:*C<<-'-*(C67"#75#+,B!#")64?#%?!/%)!4>>F*>-!6:!(5B5CBF!?A*6;?3!;C
@r4041
TGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTT
+
/;.1'=.46=!?%DGD29.#'1DDF$A>@%)56&!+@33C-B#)."A<;9F/"H)31:".;D4<5:<EH&
@r4042
CGGGAAGCTGACCACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTAAGTTGCTCAGTTGC
+
8CGG:-.5B--<=9<@#,<,5&!A#9;!&<)677#.CB/;&AAA,$A0$(/B7'F"$-C-8(1A?;H$"F(9(?3EBE<5C".66C)7*"7F9>'3<(
@r4043
ATTGGGTNCTGTGGGCTTAGTGGTTGTAAAAACACCTGACCG
+
)=")15D"(08#"&=+C!H6%=H=?8(89=-/?E<)H(#+:,
@r4044
AGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGNCGATTTGCCAACGGTGTTCACACTGCGGATTTAAAACTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATC
+
G54!&#0#G9'>"*-<//-C?4835$2)(0!@;E!@1=&4/0.6(*(CG8"--5)-&,<#"?5(:FC'$)9"."C%,;4@##@:GHH%0:EC07H@B?*1@DD(H'.82@!@G7>+(05B0>E<2,C'-'!43<"%H3*6D9B:%:=BB"9-+E<D;0/38BD(2.A?'C:A)=H8E:#;G3G5*B8<@5"*"D?3#D4)-104)'E0"2>=9D5)/+?DHFF&&*!7>/D0E21#3.6*9GD8%A!<-9'-;%-FD%+<?
@r4045
TTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAAAGAAG
+
,=4C(/3()/5,59"D(-#FG9?10/-E*&2:G6CDB!C/#C/!7")69F2.&(G&;5#1<,!#!;6"%:!AGC2(#'7A-!-CF09(.:!2BD+0'+57E"2H('E+@A?,8D4$1=!<D2?0)&H*':.@4D2>E,)!:#"ABB4794"DE+')2@".B.87<68#?>+8A"F
@r4046
ATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGT
+
-?:3%7=,D08E&$C";)@-B;%3/"3=%)6!+F$3&C.6'
@r4047
TGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATNACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTNGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACAGTA
+
5%>,>',5B@<H9%9*B4@>(@!8-F"&C,.42H"<>G1E$34&E$B74H!=5F.=3='EC?2B04(7G7B@?@,?D&87'<>A:A5*02D?H&GB:4A,H1(8#E.@A0,-E/H1>067?-GD/@?!C/;++@#5-&?%,
@r4048
NTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACNAACCCAGAAAACAAT
+
&(E1G$."3E9C1@6EG+B2A;-A<5&G4"8>1+=099,/*C9-G5%,G;E.G2HC
@r4049
AGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGAT
+
3"%;/-B2))7,'<10:7H2.+%1+>"/@"E4;+#?=B>EG;,'"66C2;
@r4050
CCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATNCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGAT
+
;E6E(@/4$.B1>096@G15)H5-G'(+6"95:12%:/&?EG>.9(DB+D)8</.@?CF45;=.G$DDB>C0F"A'-.1,/5./F+!<3'?0F=G>@4B378()7".#"6G-4E$5"+/"'<&2F:8C5
@r4051
AGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCA
+
<;5@.'"#67&0)*CH7GH@*H$*/&58=.!(4F$E&B32?%H?'#B&E)+)G7B1A7(H9F>.D-/43G>B11H'-5;33*'/%0HC,?%(
@r4052
TTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTC
+
GF@!-6!H6F-F07'>1<"GA!>$"8-*$;;F&)*8,!&HG-H3H75%2>,!?-9EHE=$!'@G=D50),($B"$@B+!4/3
@r4053
CGATCCGAATAGNTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAG
+
G:C/3#H*A*FG&%/;18H9HBD)4A/,/9.C9>&)(41A*EH8"8*:0,C2;68
@r4054
GCATTCCCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGNGTGCGTTC
+
G6,DA.3A/$8F<%;=<'&H'C5+;!F%*;<:,&"'"7;($<HC+0B0E&6BE$?8/"/A.
@r4055
TCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATANGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGT
+
%=E<<H8&#05/G5?A6950)+8"=1E16<?=3$BH8HH+-(;%D@H8!?<:--#68%6'9.A#8)&1";$>-F*H2>60).#..$CH-"9G$G##F8F$,>&F>F,AC@C)EC332+.0=/-0<<G.F)B@9G,:FBH285BA98"3?0H.G00"3:)19E/GH?<G*85E<C1&<2%D'#;AH(:=B)2A#5$&A9:-C3/EA#%EC9+(.%.(6&C""8!-/4$'>@.5D1B2&0=<-HAF'32F9!#6G:&F9B(>.;<*C'
@r4056
CAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGNGAGTTTTCGAATCTTAAGTTTATCTTTCTGGTTCTGCTCCTGTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGNGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGC
+
D8(6EB&>A.!@%36?=F-E"'=#%A/3=;%7+./$77.?#3&B?!&7F&(1?))/!;6/")2&G(H#G<:C2+$9(@D0E7G."7!.&";.;7/$>@F*EG*3:3CG9$'=4'D;==%"5+3@*,@0??'!3#(C"7E(##7B".-0A?!+;2!7G>*C0B,'A&!AA!68&4:FE;7HG=%"G06*,F.G3:@4'&(E:=!?>!.%F6.#C04"'+:'G69;-$?0!.%0%4+*1E"B=:$$1FFDB6C%A(A(0,$'/.9:.C0<A+72!(G*%%1+D.E=@!<!1B1#,((98D:+9;;/<DE*(GC%F-E6
@r4057
GCCGCCAGTATCAATATCAAACCGGGCCATTATTATTACTTTTATATCCGCAGTGTGAACNCCGTTGGCAAATCGGCATTCGTGGAGGCCGTCGGTCGGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCNGCAAGGAGCTGCTGGAAAAAGTCGAGGTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGG
+
<)<-$1=34C"<AFF:1G&5$51+G':0+(+$/')$;'01!AA*0-9-F*3,$A,+(>?2/$/7F;:#H"93-G">6,/62>.5'5)=;/84))E416&'"@"%F1<=375'/F!,A*#-=><C&5<&&E)=2!E1/1.G+B#$*&>B!*/E*?;1:1=@?GB)2H%.!G,=4;8>F64C)&H=9(7>*7@+)"17==!30H8,!2F$F;335':7+6(,#/0-*$*@12+4F=>5@.&2=:,A/)=5:$5)6(<!G//E+,.BA7H01'
@r4058
AAAAATGCGATATCGGAAATNTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTNATTAATAGATAAAAAATTC
+
;BG06>'>:9?-+<&?A%.6'C5.)8126G"/>C96C(#3B@3G$C.6;@2==0C,2:<B>#5%:-!#E4D)H<34430)D&%>'$
@r4059
CGNANCCTTNTATTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCTGCGTGGCGCTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGG
+
(')#%#&(!*(#)+'$*)#&"&)%+$%)$!"#+*')&%$("+%****#'&!$(*)'"#!"&#!(!!*&*#("'""&"#'(%%$%&"()%'#(($$%+!'+&%(!)**)$'#$"$""&$'%+!+
@r4060
GTAAAGATTGTGCCTGTCTTTTAACCAAATCAGGCTCGGTGGTTCTCGTG
+
?A:!F!564"3@4;?19(:*"1,FC%@$-/AA78$>,$>$DAC6E(B4)?
@r4061
CAATATATTTAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTT
+
7$8!-=8H1'8E;5#)H<>*C9,E0F&G97(<E9+>H0!"+?/2<$$.GE2<%&$/;DC9H@E<D6.-B!G<G?:H8.#!"A$74#D+@E7>672E:@55$)1E8H+)'F7:&(4A6+C-6B!BDA)17(+D74
@r4062
TTTCAGCCAGTGCCTCGTCCATTNTTTCGATGAACTCCGGCACGATCTCGTCAAAACT
+
B"=5&E<0A<'-0--1'7B;,$HEA6@A='13<:92%GE4>(H'?+E?)$4F*C>"!&
@r4063
AATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTNGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAAT
+
96,2%:8:9;#5)&%:6H'.<!7F-%096)3F:@ED1)G""8BB;4+44$'0=($?53<F8""G2"C:A?71;)E48'$D-#<&H$>62(/>8:@39;'=E>D+F1/D%481(F'$B<!GDH%F=,%>D$987:G72.D?+02))?C9<GEAH*F;2*!/C53?;G+.-)7##!F
@r4064
TGTCATTTAGCATGATACAATAGACAATAAAATAATTCATGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAA
+
&G5#55(D!:#HC">3#1=GE*=,G;,*0G)D?7E0+*-6>.=*4;@7=?;!8$,HF8?1$<+C4;296?:)1%E
@r4065
CTGCCCCCGGCNGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTC
+
<<4;)%!<+(F2$*;C)3/7<(H.FD;H/9>?9/(?6?-H!*3&?7)G8:C78-@A<F25&=7=9,7,)-<#G8&&HA;@!3&GAE@;C8?#*;>E<H?GH+=1@1=A2<;+,4#$=')>@C1E+>"/%
@r4066
TCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTGCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACAT
+
=/2,,B#.7;1FFC-'#0&=*;=?6"%B0D14%:@)#6;G1&H"EH;C=.2F4#H03:!A,,"A%83C'>->C?7?E#<F,,7/=C,B$,@,$:,DF-<!<7EH83;AH;3$9"E1)-1&
@r4067
TGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTCTTCTG
+
2H5H9*7;%#G26ED:6:C4E57''/3)3-1!=#/G-8<'!610,A0!!7D
@r4068
GCCTGCCAGGTNTCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCNGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGN
+
92"B96>*;3HGD&8093"=!$"D+;6E'?8>G3&*$<-0(%4F3,G%>>;/!D'4-3E<8#:!-)AE@.4<#'$#HH'6F.)B$:E:='E-,4<"?!A:
@r4069
CTTTTGNACTGGCCGCGATTGCAGATGTTATCGACGCGTAACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCCGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTCGCAGGGATATTCTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTNTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACAAAC
+
@?FGEE7("8>B=3DE-7.+7$/B>H!#6%89,3463<D!A7-=3D&9-"9H3H554#-.7(B>:-5-2AC8)D.3B>#$9%?46558((/A:A!*<<6(&=,1#>0296EGDG@=7@*,3A:1G6B@8!2!21H+5%3#/=>#,<;&&/C8C$&-#7;$-"H,$*;&GH5%@:"!CD1(+'?#!-5#+-&1F*/@<-/A9F"'%(B,>,,H:%8=51-=A3D2C/((7(".#E**.'C;/+6%04'B34!<9-5%1)+:./(%;3&.7#3GC'6G8&4@=365G;.C:=H*4EGDA%0*$;6.)>.>G(9!3=*/8>;96B283D,/'&D&8"!?817*7>2BF?55:D<.(#!"!!,D97&>&13*;1A/A)?2)%E6))F07?C/C$#1+92F+//C=H
@r4070
AACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGCCCGCAAGGGTGCCCNTGATGAAATTCNGACA
+
#$CD1%/$6?-,*#AF"DG62B,=?)#*A2/B*?!:?<-?D!$!).($8H:2<D7=58"2(=9#!+>3.,$<)80<?5
@r4071
CAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACTGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCC
+
,GE,F;.C0H0C*$EGA>,%C?>D(6C8-!-??>-'256$$+<@1:8:E>0A$>*&'D/;A*3AFDD=C>(#-$70DE"8/>FG():E;99(6>?779=4(1&:D%!"8?+9C<B&G&%00E-64)=+)C;54:HB,5!H/0+<1EE;.@H,%:)!4.#4F"A$&'G,9%E-*6F$
@r4072
TNCGTTTTTACATCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTAT
+
!&5&BD8?>28=0'6'85G68#%"8;3=0G<+1*)9'C<&<2);4'?72+A%,-&01B0+?<A
@r4073
GTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCANG
+
7"<#'HE.%>H,+>A=&F(G)8A*1=B>H=A8%42?%&'5%H7E?&+-DH)!1!(HHB>-/2";(@93D>C6GG>?%#G"3+'A19,"21+
@r4074
TGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGT
+
>:)C6B."3@/H%+3D.(B#D&<>2D#4A=6B7.4+AH'(D!/2
@r4075
NCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGG
+
#>1ED1D@?8%B))#?=2">G&%#4.$3E<0!,=#2,1:.A>GG%!/%DA?*.$9-0$(F=H3A%$2?@$24#)9+C)4%''3D,C;66(B0*H%5E@G=):%>*.HB0?($?-!H;E)!F@*8
@r4076
CGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGNAGATGTTGGCTAAACCAGCGCGAAGACGATGTA
+
&3:D%21"*>G!C2@-.C*E2<D(<A3)7(-,@.-:A5D40)$'H*=4G>6H3D-(#)CH.D&+D(3!75+.&?93&2A;$-%1'=-:79A8>+,9>D8EAE9"+?>A)@"<4%@#'$3&4D>"0+G")4(5=?&<<9G.H%B&C1HH/
@r4077
TNTTTTGTCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTC
+
&")+)%()&(""("&')!$#(++!+*!!($'%)($&'%)((("*##*&
@r4078
CATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCACCGAACATTCAGGATAATGTGCA
+
8!"@'2#,D*1CG-(DB*<-#((+<.F<+D6:/4?F/EDCD1(>=--&4*&621/)/#H:87&=,2G
@r4079
CAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATNATCGTGAAGAGTC
+
C=F,3E.)$@:5)2D'!H2C%;80!>293B<(6<F/D#=1FB."13%-D"H!$G.'C.H+DD@6C?@C#E(>&/H8>(:A-*&<*,)!51D(+%9E.(9+;5;&$0(=G:"G&%##!9BB,D'37@1?-*>
@r4080
GGAACTGGCTCAGTTTGTCCGTGTCCTCCATGCCGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTNGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTT
+
%.8D:=!9E..7.D,F46B>9@'D7.";//C881/+-?3(%;/8):;>$1H27H):->85<C2D%2@CG)"%@HA):;3()'AD+A+EE#:!4H6,0#>G5!9$'7)$30*8-E4@GC$)#H23/A:67=/F
@r4081
NCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCT
+
*<:(0"0/-HDA$$+("#0580D&6,+7!;(/06C1<:9-/*2E:A2@>0#
@r4082
TTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCNGTTATTAGCTCAGTAATGTNGATGGTCATCTT
+
(+"&$''(%&!!!'"&%(++$!+#&'(#$(&&#"(#%++!*&)$%#+!")#'"%*(%#""))"%"*+$$&"))#*$#++%+!*((+!*
@r4083
TATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACAGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGCGCCACTGATGAGGGGAACCACCAAAGACGATGTTATGC
+
A(70/<1'(B.)FC&AFGA&/?,D<<H*=+CH$,4+;3*D3'?19/79,?%4>+=;#DAD*H=?2%&&>5H*E=",1;3,*3D*"!>:58#D6=+65?("#/='4$;3E7"C%>3#4"G,&96H@F*%)?H/H%E>#?%&B>/6B'(6A;D%/*@B-G3A?4A>-#DC&:CAF<C$'FB4!C(B.*);7+,,D=8-<A*3)6!AG"AFG=>:
@r4084
ANTCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTT
+
+&%%"+$!&(('"'"'&)+)'$*$"+)+'*!&*'!!%$#")"$$%&!#)*%$'&+#"
@r4085
TGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAA
+
,--0!!,E#19;9@$>>#:.'4!6H1&)DEG&;G!0CG:H
@r4086
TCGTGAAANGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCNTTTCGTGCGCGCATAAAATACCTTGATNCTGTGCCGGATGA
+
D#%,>(3%<%.C<,.44)#A13GG1?;='1)0601.9E/"</-*-<(//5<.5$)C7#4..D&$832)(8'%=D$=2A$+!<DF)$
@r4087
CTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGG
+
H/>;-:A.B=6,(>>>8&$.8/%B$@;#(#1H'DB"=8C=B7DCA',<!<%!C0B%-B*8H-"F,F(/0A;G9<5*16A7!$GF<:!;5&>#FFE8=1D@3F8,;HE&E>1%$.5<,(
@r4088
TGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTNTGTTGGTACTCTGCCTTGATC
+
+(*(#%"$#&+)(%(&&%+$%""+")('$)+#+"+)%&#($")##))'$!'+($'&)*'''#!!+%"!)'&'
@r4089
TTTGAGCTNGTACAATNTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTT
+
!%%!$"&!"()(%&"'&+#''*&+#$+)%&)+#'&+'!**+)$'$$%+%)*'!(+#+
@r4090
TATTTGAAAAGTTTTCATCACTACTTCGTTTTTTGANAGCTTCAAGCCAGAGTTG
+
E6>;,1&#/9$'=>&G?9#2'H$()'#C%430!/G<##D8/7'6G(>3!G')#>&
@r4091
TGACCCTTACGCGAATCCGCTTCCAGTCGTTGACTGGTCGCGTCNGGCAAAAGTTAAAGAC
+
20;6"18+9-E-+@=0C+:,)BG:>,9!7!!$FFA*H"@+@5!)H.0H,6@7.9.5+;+$1
@r4092
CCAGGTCTTTCACCGCTGTCTCCAGCTCGGANTTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACANCGCCCAGCCTTTCNGATCGAACACGATGATATTCACCACAC
+
+7&26?5>$"5#D2$>92'!$;?7(G6$:="77BFA!/ECF9:;99"&3A2<E;<7.=#BG.G'*B;@0,6?"7%&$3G=H=5):<1H03-(:EC0+DD-B))>""55!.FEA.#75'DFD$="FE2@1
@r4093
AATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCAC
+
.G4;8.+!;.2H7HEA$6@(35==4DF"CC6=A>;&2+#!/3!&+$-3GB=1!+'$?!'2*#$BCE!+7>H,6#8&9H:%;A+?A<F75
@r4094
CCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAA
+
+2+5$>4E(1C;+B5;>!E8?/=>8466-A*&,;;C4!:<%8-7CC?4D+28>H);!)388:;=>;=,",:<<GE2B<@G6-6A;+#F=0+#'
@r4095
GTAAGCGTATTGCTAAACTAGAAAGCAACGANGTCCGTGAAGACGGAAACCAGTTTCNTGTTNTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTNATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCCGGATGCAGGTGAGT
+
?@2/%5-8F>7/9?74;0:6E&$2!#F%#&7*!)B6=19AH+5*C5G>(4@F*655BF:?0%).!4*5C5645,"GD00+)4434G$6F=$CGB?<@&'/C:7AH6H3D998B+:B)9@E+.""'/B@>#(/8>8.F?%293$A33:=4.,7@#1/@95)?+A-:78,01H-./C>7@5H;BF0##6)'D&()D/(1/>7763%B7>FGA%:$,CD/@.AE<
@r4096
ATTCAAATTCAAGCGAAATGATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTC
+
A3;#';;$5)''/(A!12'",;.2:/3=65?,>03E!%#E@"==0#2A185:A"84:'$?#,8/5&:.*,'9,A;#C%,8:1@G#'?
@r4097
GGTTACCAACCTGTATCAGAACATGCGGGCCAATGGGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCNTATGACTGCGAGAATTAACCGTGGTGAGGCGATC
+
.);5%*C<*$+&76(8>(1D6BF7DDDG=/26.6!+DH8==:9;"9;A8C!$#B-H+>?2%,044;"CD,*8/C>?<B(6FG<E/6A*52(&GGH,>&%(D=B1A;$B;;90C<DC>F
@r4098
ATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATA
+
*8.86>G*H$#-.';D!F&$H?FC60,>4A>6*0B).$A+8F
@r4099
NAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAANGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGNCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAACCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCNGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAA
+
$D%.(GEG0><'H8/"C5%-G12BE+HE$,="/&2"1"2D'!;#%+.7&2/;.=%(@",,)//G#BH9"&150A:?=+*./5=3%8H/1-B"46D7D2--D5?0H#AGE9=,/C=-G@>.>?52(2(=);?,,).)";$F'77/4<&;B&/3)+:>*17-&:;(*#(A)(14@169?13-5+$<=69#*#F/<F>E:"9+?C&>6E:-=>%@,@.&<&D"E4FA@D@3-4:4*8-C+.5F-'$=<<*/?HD=D:"G75E(H>1#!$G.0/+D+?1G4(3#B
@r4100
GCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTT
+
::3F@)$C";!&=%2&.*8=6A@F<BG<:<D''5B+4G>(C0:?<+&,<00<8/(4+@;21+-'>06(D=HA!=CC,+30H$)A:B59#9A-*,<#=+.;0&D5%C(8'D$8G7.1+@C@+6/BDE()GE=,31F
@r4101
CGGGTACATTGCCGTCGTTGTNGGGCGGGGATNCCGGTGTGAGTCATCTGAAAGGGATTAACG
+
H&13C%)?$H+!74./1"0&E.C8=!D"E-HD!?30?$,,G4F77.&E%'"@#FB('0?)=:,
@r4102
GTCNTGCTNATGCTCGAACTGACCATAACCAGCGCCCGGNAGTGAAGCCCAGATATTGCT
+
*'(""#+'&*)!)#)*()*&")"#('"**%*"&!)'!)*)&!%%#)&!#!$&+'!(#%!#
@r4103
TCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTT
+
FE"H7A07#$H18$/2&4C15>:C$(>$+3F-9=;F,,$H*!><6$=/=6$4.91-,1.;&%0=14@,<B%:>1
@r4104
GGTTCGATCCGAAAGGCTGGGCGCTGTTCCNTTCCTTCAAA
+
#+'+*$##(#%"!&"!#%'*+(&"&&()($$&)%$%**!)$
@r4105
CGACTGGAAANCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACNAGATTAA
+
;#<@98#G0>"9&4<92(5"60&3B3"49&=*14(+49)7D$+'+@$%9*!%8+@G&+;:=*D/+B-9%11%
@r4106
TCATTACTCACTTCNCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAG
+
<H0AE$G/DGE7DFH3FA!A70CB$,&G'.'&=,?!H*)73-9?0,)<7)33%8&
@r4107
AANAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATAT
+
%B+*3.2A,E-1#7%!9/4<B"B6G5''&/#(7"E/2@G1D3>>FE3**2,0!'7B?7+2(<G7<-599=(%*)2FB6C2#,-&8G,DG4;9(4:%H,3(D47G472<;7>B+*8H.!%.#'=/
@r4108
TATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGNTTTTGGAACNTCTTGCAGTACT
+
F*5E$A''B*2F64>@#%<;DH60>7>")86;0+#BG$=2>$!CA"(*%-")+"!A*1+D!E&;#
@r4109
TGCTTTAATGCTGCGGTAAACACACANTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGA
+
15+'&=":<FH1,=%+*8D56H.,):F(:68>C$>28/F=1,1F3,AH?8'7C+5,9!75;&B,'=./'%,7&(0%F:;9:'0/9)7(,#2&)/>235D=#@?:/$#53A7'/8C?"D<*21=+F'7->)'+("$<*:
@r4110
TTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATNGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAA
+
.B.4(BG?=E*0<+9'37*)9+#'+<A2/6&5/#'H<17'#%%E@D&<$46#(9G)A;G)/G%*@;'+>/)5(*A0<D%*#2874@+(?0A;C;"7,28HA3.'<5
@r4111
GAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCATTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTC
+
4.D<9'5@7?<>,'24D>*<>:&@%4;?9.,@%<H'=F)*E;1:BD5&AFH>4ADC?+/GC:48#G4+;?$C7'#+*<#=-);7:)0A3,#-:'25#2F@2#:7/&065)G'$B"G%*'?/'E(%$C$5&="(*"<A719$6-$$)DH:"=<9@8?8A;&<G:.);;E.&H1?>,:?FDB(+%;@8=.@"10+9/%
@r4112
CGTCGTAAAAAGGGGCGGCGTTCATCCCTGAAAGGTGGCGGCAGCGCGC
+
G%$"=3"8-(6*C,F#.3+2&-"?E?98D<G;8";D7+'7:.*-=/28:
@r4113
CTGCAATCGGAATGCATGGTTAAGCCTGNAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGNACAACAAAGCTGCCTGAT
+
*9/='#>=B3GC?/A*+$4-4=C<+H6F150DH%+1H41C5"6?(:005A%2"%7?'"=C%39--E*->79'=AE&A(FBF;4#!86*)+27"8C(D!")24*3DE&7*,4!//D778(*6/%7615+#18,'%CEEGF
@r4114
CCTCTGCATCCGGCGTGGANGTGGACAAGGTCGCNGAAGCCTTCGGGAAGCTGACCACAGACC
+
D317>@A>FCB@:D5,E-?9*,A?=!1!734G#G'.F@(%.3;@)3>H$#)-"?53G2>,@>H
@r4115
CNCTGGNCGCTNAAAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAANCAACCGAAGAATGCGACACTGACGGCGCTGGCAGCGCTT
+
&")%%"$*'$$%&!+(&"$)!#+*&!%!)'"!"+&**&!((*%&%&#"%+*+$&+$!%*((!%#'&'!%)#*#"!()#)'#&(!$!!+%&%!+'+#'$%#%)*!!%*(&*&&+!*!$"'#(&+)&&+)+%*$'!
@r4116
TCTNGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCCCCCGGAACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGNTTTAATCAGCCACAGCCCGGCGCNGTGTGCCTGCCCCCGNCTGGT
+
#()!)+$&)'%$*&)&"'$&))&(!$'*("!+#!$#("+)%&&((('"&%%+!&!*&#('&*#&$*+&$)+"$(!#"%!"$$$&$''+"%%"!'$&'#"*#($&%("+($*(+&'(!#&'#)"&#!*%%""%+'((*"$%!"('#%(!"&+)")&%!')'!""#"$+*"'+)"!*'*%(!$"#%&!+'*%
@r4117
GGGTGATCCCCATTAAAGGGGCATCCGTCTNCGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACGAAAACGGGGTTTACCTTACCGAAATCNGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAA
+
0))0HB3ADC+&)@C&$@(3.;@8,>='!#.-&9!2<'5D!0<.)@9G'AHE0<@8$*)83@*#@>!%7+.!9)-!::G38F;E1>G%>H61'E,'>')#11$%&D6,,+@*9&&1<=#(:,G9>0'=#?9./D$8/="D-3:DAB?(
@r4118
CGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGC
+
#++"$+%)&+''))(%+"&)''"&#)*!+!!*(%+&&(%)!"+)%*!&'!$($)+"#
@r4119
NTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGA
+
(.=G>!1;()/4*2:!C//2%,/HEB<26<>%6CG:<E4!(3&E$=EG<#C-%:0!:A@48(83'6#49."!F!G%<)
@r4120
NCTGCCACACCGGCAGAGACACGAAACGCCGNTCCCGGCAGCACAAATGCCACAGGTTC
+
,6797"+7(&"=(9!>D#-4=3GG)*E*,9A+DC'6DFD%9AH$0.#9;!0%CB-"74#
@r4121
ACGTCACCACGCGGCGAACGATGGCCTCTTNCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTA
+
<H.F4D>,26)0-,.DE95C6BA"535;$H>-#3#E%%;@-:/)F!G/H1)0<0=D-8%E8B2;'<3-&$A=',='#?&9'$"64(7:D>"9<)G:H24H6%<-9!B)C/%G?@?'(%8/E(@()*C*,G#6E!57".%8#=D58DB69*:
@r4122
AGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGACACCAATGTGGGACGTCCGTCGATGGCAGA
+
(6%AB-&E&*FA?/+-14#*D*43'4+EA58@<'7)D*<;.H6@G;+(<(=#5690(-?*)3A;HC6C+>7.-
@r4123
GTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACG
+
#(<4??)C'%F;-1*72AH3FBG?/7.'B&1/H!@"#?2;"FD@G9-@7?6<)%A80D?"B=@2A6C#:$#$F-(
@r4124
TCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGNTCGTTTNTGATGATTTTGCTGCCTGTTTTGAGGCCAGCGCATCTC
+
6@B#$@#&$97#*G,1@;F?+'74,E=BC<C22C%3FB8"%*A!G$!:9!F'-*%2=:%!:8<9G339:>8"5-)C>11+*#E'@9%)F913&$-$-"8C,>9'5/9(H63?AEC&1'/7H:61"%"F>
@r4125
TCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGC
+
87<#-F:-"*"3*9=6&E,A53@3;4H#%FB$&*%.A<)C17E>5#39A>"+49!),:A$H,(=G@BH$54'<C#E=B:</;*4H>6(*CFA-C+2
@r4126
NGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGNCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGT
+
$.0*C;G$"D55'A4*!&0(,3)1'C*A@FGE.;GD>D@"C;26-FD;:6(91'3C!-A?59G34*&.,)5$!"GB'*7B'*@9<<3(6.)#(.(!($<)G:)>$E5+07ED-=<1E4(H+%$(H=,79G<=3#-;1$5*(31(<9/@,%+9#)A%#7G93%/#891#+7
@r4127
ATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAG
+
5FG3(*&;5<&1F-7DD&':'"%+3;*3@1#)8)<H4)B6=*;,.!5E.-F&+!852
@r4128
TGACTCGTTCAAGTAAAGATTNGGAAGGGCAGCCAGCAACAGGCCAC
+
7B5;<%=/%DA8@=/#*0)038G6>"4/19-+:"G#!5!1$?+&:03
@r4129
CTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACA
+
#HC&%(.,@+-%207>D-"'0A$+5;4'"E-&##F,'@,G<G3A5;(5')$6"5D>-?5B:
@r4130
ATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTG
+
-'@!H+3G+/F2A"A&-/>C>=$D((43/F5H&*"?99>%$G1G,G,E#H!C$2)E6#
@r4131
CCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAA
+
$H67753E3%#)!#-'1#&29E7%%A%8A8E&+H=C:/(")5$A"=4#A23>&DFH7"
@r4132
GGGNNTGNTTTGNCGNNNGANTNNNNTNGAAGNGCGGCCNTNCNTTCGNGANCNNCNCGANCCACNNNCNNCANANNNTNTCNNNACNGTTTTCGNNGNNNGCNCTNNNCNNANNTNNTCNCATANNNTGNCCNANCGNNNGCNNGACNNAGTNACTNCCACCTAGNNNTGANANTTNNNGTNNCGAATGCGNCCNTTNNTGCATNNNATNNNTTNANGCTTN
+
!#$"#!!!$#$#$"##"#$#!#$"#!#!##"#"#!$!##"$#"!$#$!!#"$$$$!#$!#!"""#$"!#!""#$$$#"$"!$#!$$!"!$!!!!$!#$!#!"#"##"#!"!"!!""!#"$#!!"""#!$"!!"#$$"##$$"#!$#"!$!#"$!"$$!#!""#$#$#!!#$#!$!$$""$"!!!#"$"!$#""!!#$"#!!#$"$##!$$#$!#$!##"$$#"
@r4133
GCATACGATCTGCCGTCNGTCCCGCCTNATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGNACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGTACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACNATCGGCAGGGTGATCGCACCGGCAAGCCCCCT
+
*(&*$#!()*&%"**%))$&)+*&$&#)#'"!"+'#*!$#!#(+)%+!))&+$#))')"#$'!))*"!)+%)#'('"+!%!"($!%"+!($$'*%(++&('!"()"'"#')&&!)*('"(')++#*++!#*)+("#!#+(!*&%$"'*#'&$%'")%*$'+')+("%)(
@r4134
ATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCA
+
G+8A%02<B5-$(15#?#*2GHF/292?G>%!07$C)8;0G->0-#$$3F/E(;=A+/9!3H)%.+'BG$&"&7B*<6H,E)%;2)"#$>H!0HBD@(E'9=9,/3G06$$%4E)F?447/2((D&:E9'D9*A7@%HBF<0/G/?3"9F-3?@C/:91G1200''*"
@r4135
CCGTCGAGAATACTGGCAATTTCACCTGCGATCCCCGACAGCACGAATGTACAGAATGCGGTTTCCANCACTTCAGCGGAGTCTCTGGCATTCT
+
)(+#(&&$$(*!%!(+*'***()&!)#*)$'##)&$&"#&(+!&$('+)$*+$("*')"&'&*##)%($'%*)!)('+!*(("!&&)&%%$$!'
@r4136
NGTNCNTNAAGGCNNGTCCNCACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCC
+
%*'")&*%)'(%*$#$+"')"*+%)#*""(!)%'('#'$%"'!)#"$&*)'"$&$*(#*'+$'+!!%&!"("(#!*#'")&&&&)"'!#
@r4137
ANNAATATCNCATGAAGGTTTNTAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGT
+
*!&*%)&)+&"%!!*#"*!"$*%""#+&*"&($"%%$&&%%!"+$(*%!+&*#&)%&''%%'$%+'+!%&%!(%"))#+!#)(&'"("$*#(()$))&(+'$!(!%)*!)$!%$&%#"*%')'%#*&*
@r4138
CNTCAGCAGGANAACGCCCTTCGCANCATTGCCCGTCAGGCTAATTCTG
+
'?@?@-2=A?3DF7>/4-@.8A=/C%=0#/:'4GF5;<18%-!07=(9>
@r4139
GATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGANAGCCAGTTGATCANCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTG
+
AB+7!D::2D"''6=G24D'*-?;B"09,><CG84.B)1'=&4+/=+.D(G#,F8%-6;.D:(:)2=9(.B5&"03@<0@B=+<1H<:A"8(B.88H?0;28,A47(@3=0B%89"(.B1.8$D*'
@r4140
CGTCGTCTTCACATCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACACAAACATTGCTGATACCGTTTAGCT
+
AG9BCA@;$2./82GD2$7A7$<4<&?<G:!!/:G7?(38-%F+B)2*1&:769<?4/2/>7%'):+E;+,.,';HB00>$3BB(F@C2<;-5?7#+.D<$=:+3.*8-BG'(@)1
@r4141
NCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGNTGCTTTTGATGATGATATTGAACAGNAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGANGGCTCGGTCTGGCCAAAGTNCATCCGTGGCTNCACGCNAAAAGTGAGAGGCACCTGTCA
+
%A%97)C6=8DB636.BF;"62*4FDBH>->G>7/<)55.::*)0")<&$H7.:B!!'5%C.DF6$4&D4(78%#AFG&,!++2%)!%9#5E(G+G/."0?B+G78@:A'GA?0*@<AH*=&="F"D*!A-/+9#3.!C#,/#?;8B"H#4;.94;7%27;&0@8(4F98!AG$86,2D@-),@D>08=!<=9)?4/?(.#C#:7C.G8H?"/331F.?+7A//62AC75*H5=D733G=<:D=/G,B*=:GH-3'
@r4142
ACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTC
+
/.69GCH3)*H('6308*!;3%=.(E;42@F0"#=+3,:&/G<?
@r4143
TTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGNACATGGTACGT
+
E()C,4&-C&GG11%?&2!;6?1$D3(,0#!4=GF<">&(:5.&</8(,8$B?,*</E
@r4144
NNNAATNCTTNTGCNTGNNCTNAGATTNANNAATAATATCC
+
#"##&*$)%'()&%!($%%)&!&)"*($)$##(##)'++*%
@r4145
ATGGTTACGCCAGACTATCAAATATGCTGCTTGNGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTA
+
@')@(=2+6;;58(#0/791-+0";:!!8-G+5==?5?,?BD#49/D.2/8GA"?/(HE$)1D,+@+7G:@'(2)D6(7-EHC2411:5"0D+.>)
@r4146
TGCTCGGAAGGTATGATGCAGATAAATGTNNGAAATAATTTCANT
+
,+A'C<15>;$>,G';E.-%2$.*"&,<0%H?;D+0G4*3-B@C/
@r4147
NNTGCGNGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCANCCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAA
+
'#&&%"#'+#(!#'+*+%'**%+**'#+#%*("'$&'"*)**!#$*')$+!&##*#')!++$()#)(%%!&%("(!%$%#&(()+**
@r4148
CANCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATNAACCTTCATG
+
#(!A(%34'5@:5F+/9AH20,3<.C)!$7B9D$9'E4C*C.>H@HD4-G(73)7D@>,DG3<!/*B,$-A,%.15H)<0/2A7,>F%!?0$?0!
@r4149
GTGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCAC
+
+)G0<H'3D9>2G?BF:4(+G6<;.H!A@-18E+1C8"!B$C2
@r4150
CCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTNATTGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTNCATCCAGTGCATCACGCATGACGGTG
+
8@-H70%2$8674""A,:9!6H'$"A$*&=@FC3>*>-(=.4F6AE@%F4$&30-)1+*'H?;?##C3=4&*E;$E,;ECG1E!?)=)G$G8:+$<H$)3.):HH7/#"!#=<F;7,G?!/$
@r4151
GACATACCTTGCAAGGAGTTTATAAATNAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAG
+
79=.<(HG($/$*!DA*A@G!E(05"&CBA;.6;+!G=$A<?4)7.,%:-*)H2==&!-:6*$C)EH851D;+&')H.3#/&-GC,=3%'<.2?09<2,G8#**<:C>/-AF*7@")31(<HH+E"(8?2GG'A(<4%+0!D?+CDEA@4.14!-)2<:<6675&/>(-=1-0H>
@r4152
TGNTGACATCCCGGCAAACATGGCACGACAGTCGGGTCGCCCCATCTCACGNGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGN
+
!$!*)#$)+)"'#%&$%)'+#$("('$&"'')(#%(%$((')$)*+!%!&($!'(&%)%&)(*$%!*('&()!$&"*)*$((++#+%'+*#)*&%&#&*!**(!#!!+$#$&+'&%&!+'!++$
@r4153
GCAGGTCACCTTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACCGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGC
+
.0%C9(D,"5FC92<37#,6##;'1+C/4?)$!=4<F1-/<91'/>2'?=/"A:9(8-%9"<14AH),&B$75,B@#4'.@99-=,:)>4)6D1D25'>8%%D-)6,45.<B.9302?9E7E3,?96?.E&8E<-5D8#-8)5.6#9GA&($*8G<
@r4154
CGTCGGTCGGGCGAGCGATNATGCGGAAGGTTACCTGGATTTTTTCAAGGGCAAGATAANCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGT
+
(-,6A2"&&49)#$H'@"%"H,+.$'2FA=*%";(60'!+-DF#">-@+/(,$-.=C@/'3<D?(-/*E+5H6<6C32.1&)D#G$6AH$C2BE/G9@&.DD?73<.C>2"17;%)A141".,5H&11F4A362'D#/.<)D-!=#&3A"69FE<5*!A-:%00F'6
@r4155
GCAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTNACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCTAGATTTTGCTACCACCATGACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGANGCCGCCAGCCTGACTGAACTGACTCA
+
$'%<5+%723,#FEC%*))$E8)<8$@18>*0"6F!D<-1@1"@8;%2-+:G#EH0D@D:**H!+6,/0H%BB>)6=A#8=E!(=D7?8B.0G:-D,@>H,H5=$3G*1G@:E19">!:=)$27+73>;8;:3DB<B//4"F)BGDEE!3$>E@%.74?*G(E<&!5@A#A>>5!1&F3*9A!0A8!*C+?6E(?GHEB0@'9/"GH!-+8/>7#D0-F6$3>;1$BC7,9&,<C))4G&#"!$GD<,0%AH!(0H;"%*$:5$8F*&@
@r4156
TCGGATCACCGGAAAGGACCCGTAAAGTGATNATGATTATCATCTACGTATCACAACGTGCG
+
,!/%52/.?/"1G'6=<B@9)=?/!?&*D"6C#-*!-140$@5(:7,9@54>;+"(F&6@@4
@r4157
GGGCAATACGAACGCCGGCAATGATTGCCAGANAACTTGGTAAACAGAACAACAAAGCTGCCNGATAG
+
<1E3140@6);04BD>H9<.&*@.2*)5A.7@'"8E-8:F0$@;)1!+H3@(&H<1C(/68858-3EB
@r4158
GCCATCACATCAGTACNGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCT
+
$>.4?0B&9&A;"FB#;8B5%698C4450!=1C"+#@/'CHF*'6C;0>%38!.A2!-2F"D?7)$%8H98BA%+:';#8F#(/D7G4*@4H+6,3%<33EC6':%$",G+B;">8#0D*
@r4159
AACCGCAGAACGTNATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATACCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCNTCCAGGCTTCCAGCAACGAGGTTTCTTCCNTCGTTGCAATTTCCAGATCTGCAGCATCCAGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCC
+
6?(3%'"E):$G%)&.!=9D+&%4%4-=D.B8B9-3;+/,=2DDBB9#A!)C6G!%6=;&7@9(E3C@1AC#";)).(B9!?')G6,<$1>#2.F:A+346+8/5A"D1&F-67-.>&292=78%!F!<+%72E)@@:,F9GDD76*<4!.95@A:5'8<7=76)")$+0(;FB)#3'6!"F.;"'CE;$HEE,E4<*/2"6,FC1CB$&!$9!2!&8?**!54.((-!7)1*B2.)34."';<HA&:99)D@4F.H
@r4160
TTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCNCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTC
+
/#2B"9=(/):/3=3,!;+*F.D:03F</-7A,$""&$2)BH57GB?A8(A59>F.A9&;+8H=-57=/;3@1,3EA'C/.#"
@r4161
NCCTCAAAGGGTGACAGGAATCCTTCGGAAGTCCGCCTGCTGGTTCAGATACAACGTAACGGTGGCGGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAACCACCTCGCAGTATCTGGCCTCGGTAGTGATGGGTAAACTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAAT
+
!.=H@@2%?(+C$G8'&4<C<3E;=08)F!<6F4C1B,0+5$5H<)51*72>#93$A/1?(!(8G9B7E8H"9!))@<)5B3D%":.;)C68B1!5+#!1#D;1*#=00F>B3&>(F1,4?":40E0;($/1"832639!5H'.D747/8G078D99>4=?-?/.4)+'C5%@/&6.(B'?<51F1;/G)5C,,@)&*ACG37'@4!+@@,%;F+@B=;05'=$>>$4!1*BC(:8;F./0$
@r4162
TCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATNGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGG
+
H:3!&$6,"@+!02B8&=8<9+;0,!A>C-'/19+>&"*&D(-/5B%:"6'455&5#(5><=$F,2AC1#")-.AB@G/E3B6H($H@1=6&0-C@6F-2/;D!$H@FF.'$78G"G5/#@B(##3ECG33$12!!@$"D6$DACC43=
@r4163
GNTCTTAATATCTTCAACTGAAGCTTTAGAGCGATNTATCTTCTGAACCAGACTCTTGTCATTTGTTTTGGTAA
+
+0/3HA"?<+(F5#+C??;D2DE6A>>,EG%1A;;+5(=!?72&F)C(/5(<C1A3@7<86DG/A9,4>+%4G#
@r4164
CGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGAT
+
7B7%$)+G<%-2?C5<$)$H!(+B5@7;119(:@728A9H1HD+$C13)&''5%9C/-D$E'@?!F<8
@r4165
GGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTNTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCT
+
%/$A5(GF!=7C.3GB-A0,C;9;$FAF96H9+G:#C,"88&0E:/2#4AD!90@A29:1(/"<71+531D5E+'C7GA)<7.03B#2.2-FF#+@B*4.5F"A9:.5!-#0F9DDDG*HD1?,3+!&99()*(A>"@C;<;'9<AF0&'D*.+&&CBH)(E2?>!130E>=*125A"/E46E$FB'!)+!=#D<C2C.,+#H!>!2C+"2BB%3+57$5AG&85(*=(*;D
@r4166
GGTGTNGNNNACNNCANGTNNCNNNTATNNCNGANNGTTTNNGNTNCGNNTATCCNANCTNGTGGCGTATCTANTCCNNNNTNNANGNCANNACNCNNNNANCCGAAGNACNGAGNNNGNNCTCANGTCNTNTNNCGNNNGTTNCCNNNGGNCTNTCN
+
$$$#$!$$"#$#$"#!#"##$!##!#!#"!"!!$""#"##!"$"$!!#$#"$"##"!"$$"$$$!$$!#"$$$#""$""$!"!!#$$"#"#$#$!!!!!!"!"$""#$!#!!!$#!#$$!#$!#""!$!!$""!#$$$!"!$#$$$!""!#!"#!!$!
@r4167
CNCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTT
+
$&8"C(H>C9DA-!*,F:7(?H9$!4"(%';1E=>A)(<D=!71?;C=(6>16A13/!"4"(42(/(2&42.$H7)2*F.8%'A3@A+C
@r4168
TTCCCAGGATGGCGAACANCAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTGCTTTCCA
+
:6A<G*<F35%-?$6).=780!!*"DC?!1@C(HA$!=8>1:3*10B=&1)06B/&9&'/8
@r4169
CGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACC
+
*43-.%*1&;41GF,F4F/D7,E,B(6>G96HG1D.<><2G78*(+,=*@-HH"'27
@r4170
CACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGNAATAACGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACANACTTTCGCAGTAAATCCCATGACACAGA
+
+)#'+!)$*%$%$)*)!(!$!&$)!*+&"$*(#&((+'(&#&$*%"("!"""!'&(("#($!(%"'*!(+))%"*"!+)(#)$%%#+()'&%*#)'"&&*&*%"!+!'!+!%*)+
@r4171
GANAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCGCGAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTNAAAAACCAGGTTCGTGCNCATCTTTCCTTNCC
+
0C9A&885#EB1&B2*81-0/(08.*8.EB5;'!%3,8:6+-@()H*@;48A"5>%6>/G3.:>#C;H:+9B*>$E,H++!+;%)<66)&F?B2FG8;-@H@()8*/)$"@-,>(<(-:6($94H!-4D6.B(0+B//'21,60.%@H2
@r4172
GTGTTTATGNAGATGAAGGTNTAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTCATACCGTGCAAAATGATTATCAAGAGTAGGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGAT
+
"(?F85@0$D13B!<<1#6'GA2*D9(>-&-:5&$'&2*FF.$!8F!2--B";ED'%8AD8-A.5=4")H)?2D8/+G?B:#F4%3A9;-.?'75B+&9'%A:!(/$'8%5??.A&<:04H6%:<?(<'>(?G@<>7F)B1%>5(D<"=G#?G/!=8A##>27"99*"A!!<58/1,/@#+F=+>
@r4173
TNNAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCA
+
"!!%$'$+*&#!)$*'+#"(#(!+"+)#(!&#)&&&&(!)$!*!)*$$*$#+%(#!'("%&(+
@r4174
ACGGCAAATGTCATCGACGTTTTTATCCGGAAACTGTTGTCTG
+
H<7(E"/AF?9@+@"45*$1#C:402&/?0B:>(A)9"8:C(8
@r4175
CTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTA
+
*=A7%=&0D4#7">2(G<FG!7!/0F<F)13:"0;@,HA1;FH>93.8=0%
@r4176
TCANAGNNTCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGGCCGTTTTNACGGTCATACCCGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTT
+
*$)!")!!&*++)*"%(&!"!!%(!'&$**!)""!+('!$(+)&(!''$+'+''"*$&(&'*&'#%*)((&%!#*+%(#(()%###*!&$*")!('()*(%&"(%+*%&&!+(#)'$$#'$!(*#!!'"*$)$!!++$#&!'!&*&'%!&)$+)))))*$%**%!'!%#*
@r4177
NTCATCNAANTNCGCNGTTANCCCGGACGTGCTGACGTCCCGCCCGGCAANCC
+
##'*)#(""$'(#(%"'&&*#+(!&+%"'!&#%)(*#$$%+$#$)!*$+"%)"
@r4178
AGGCCGGANCACCGTTCCGCCGACCAGACTCTGCATATGTTCCGNCATCCCGGNGACCATACCGTACAGGTTAGAAACC
+
)"))")')#+#*"+#*%*+''"&*#%")))+"*%#%(*+(+)%$"*&'$!#$(+#%%(+)#")$$%#$!'+*'')&"('
@r4179
GNCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGC
+
-!FE/(0$;D$35C"))GB'"@"+GGDD':.>85%!7E/*E-5HG(>-/*"
@r4180
AAATAAATCCCCGCGAGTGCAAGGATTGTTATGTAATATTGGNTTTAAT
+
HAC3#=@+%#&:B3?&0%B6:0'4!9)-?/5,05E%441!=?0**?,2C
@r4181
GGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTT
+
7*G#G1AG,;++.*7AD=!(++5EH+>:D=*05>#F9;7$H,$0FB/*AAB$6D'='D*D7@8-,'9<-!9C@
@r4182
NAGTGTGGATGCAGNCCAGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGA
+
(78@0/4-('H1H)+?&*6?$9-5*;69&-'$3,)?";.'??<0!G9;1=5-@C#@">F-#E3C:+5C%%-.2$:A%6A<&.A)$%7.5@,<2..4$/9&5/.F8"A92&E<G'1=EA(!H-73B'6/3$/%#."C$@2>A-#G58:9H.8$F'6@:AE&+84E@2F=F@$3AA
@r4183
CGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCANCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACANGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGGTCTCCAGC
+
AC9+"?GB)E3F<6(6<=B!0.5.!)#'<9#8>%A/#B:&*,>,1(3>D#GE:1->*%9!)-"CF&=7".E#(66$C'(0<96!1DCH7&8,$A#E0)3$#70/<)$FD6G-?&<9/G"B*H7!0=0"(B$
@r4184
GCCTTAATCCGTGGNCGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTNCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTNTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCNCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGAC
+
'.>13)B*4B.@5D$4B,4@,,85044+5F1#@89@7C;#?H7793FG)302E7H#+,#>%E%BG-<9;+46"01D0$*.2/7&-=5"F!#$(G+F//6(!%6/:A;(6?D))#%,HG:/8+764)>)<F&.69-7-:112-H&+$+729<,.F5"H-:B%C1%>%/+A'="/')?>3&>##,#"*9C>GC%(H#A-B1$;,,!-.!86D#>H#$3F,#)D/BC)<?+A@8."&(7'A7E,/50*5;4-AB!H8#15+=!H5C!"H(@3C7).B8+B2/FE5G;8"G,=83'(.10>+4E:@:!.3'0'1A$4<'BA;/4%5'D.+35GA"<8C=F;E5E*+9-"379;6
@r4185
GGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACT
+
&/=#2.GE8;64G%=ED>.>:."D?<(19:8/"#E+?3A+5%'!7F1D>F$8E0/;7G85:;!"<;1::'(/:;"3:27B1-=(<45B3?+>;F2H(#(A$-E2B'5H<H-,*H=DE6+&>8!*64*%:F?1)/C?B?GF")D2$)2<<;A8E""$A9-B*?#=&/6B=(4//HG><G.'HAD1D6:A(@.*
@r4186
TTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTNGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCNGCCGATCTGACTTATGTCATTACCTNTGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCANCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCNCTTTCAGACGTTGACTGGTCGCGTCTGGC
+
/#/-)9'.G9==H5*+/$"A2"#$+98HFHDCB'C0$4G$A6B9+(:DD&31+9<?)=/&*E.,)653.=8E-8:4/.7$"=!#&7.2'A@#%+:,61$B(?=:()982+"E0@"!"*!E2>2D!'->??/$B3A9B;3&9;96*=>C$04.$?@);<3H(B)FAAGH6$;/.0(9-)/==)A7#?.#E@0<$"9-+H0,)C90.A$5H&6'4/<15H++&E?5&:>B&E(.$@7,&BHD?!'616!+#@5?;?B5*-18*0<D";'D!0!FF'3+'F?="G.6<6,4*=1/&;"(04!?4DDHA88$:/E35).0+9HG?%F"#615@(8!/@&>'13?3'6*8$%)>52H';0:<H255".$-1%&F+#6BE(%,#(**('?9HF,9*-5<1H<C@985"HC0B/:@';?>E>H!+6G$2"DH0(2":B@F=
@r4187
NCANCACTNTCGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGA
+
#'&("(((!$+#'&&"*+*&#*#!*%)$$++"%%!(!+*%#)(')'$*&#)+#%#+"+'+)+($&($+%$("+!
@r4188
CGTTTCCATCCGTCACGTAATTTACGGATGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAA
+
,D&>"(%BCF%$-)"3/(#*>>63;8%A3()>$D$*G#=%E;)!)*?4"+52*:/)3+;4A,E,2B>DA4FG!.D7!:C4</(-3F-::6+@:3><:?"4>A'F",>-&--DD>6>E<'1)/AG"#E'A*CAE<?,'363AF/5,5'/5":@&<4+??$02
@r4189
ATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATNATCGTCCACTTGAATCTGTGGTTCATTACG
+
G$BA>>4B!%/D$B#@'920)1%&>4A(D.6+"53'7%DAF*'2H21><(H/==)"D-'B&1'4!CDE3#
@r4190
CTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAANTCGCCTTGTTTTTCTATCGTATT
+
'+7&@./,.1,+&3;*5F#>"@2104';21C'-@.>%D!%GF,/#:C;9D4H+#+&0256#+%526#9=094;1%E
@r4191
AACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAANGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGC
+
0A5(*>=G;>&&,B=($)?81G1@!H?->*>#$1>0@#3D:0H0);@C,>G?!:.16F#:G3?,:%B@0062@=-+%+3&GD9D/E1;$GF1.%(83#@5)!)F+@16%A,H#C'1#<+<<84;0/=:GF5?H04,9$<)B619BCA-C/
@r4192
CAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCATTTCAGCGGAGTCTCTGGCATTCTTCAGTT
+
FHB9)'1:3#3GB=$67%*,"8(68&#(%1731;"/<E&C2+B/"7H**H/=A-E-CF0$'279%19E<'F*2G8C%&.<,E6C
@r4193
GAGGTGGGATCAGCGCAGCCGGATACCTTGATTNTGGATACG
+
?5!"GA)@3G(&,7,-8()3,7G02FC*1<$4(<@?8&+C';
@r4194
AACTCCTGAAATAGCTGTGAAAATATCGCCCGCGANATGCCGGGCTGATTAGGA
+
C6&5HDBE"(-'?;'+F64G3D$@5"G%56CB)A29D/>!)$!28(&9"=A4?>
@r4195
AGCGATTTAAGNTAAGAAAACGCATTAAGATGCAAAACGATAAAG
+
A&425!(#*3EG&/!#%H(/F30542;1!>.&:#=D2G@#E@-%+
@r4196
ATTANATGCNGACGTANNGTNTCATACGTTAGCCGCATNCCTTTCACAAAAGCTNNAANTGATGGTNGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCCATGACACCTCAGCAGGAAAACGCCC
+
)($*")(%)&%&'!%$#%"$'+(*#%%&$!'#""%!(&"'!(+""#(($)+&$++$+!!'!$&)&%+"''"!%%*&$&'%$)*%!'""+$*(''&*(!)+$)'+%$&#")%'+#%#)+'%!"!#'(**$&)''&(!%!$"$%&#+#+"+!'&+$#'%&+)+'%(+$"('%!!%%)+#*#($#'("")%%#$+(**)!*%&"***
@r4197
TTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCNAGAACTGTTTTCGGGCCGACCACA
+
8/+*;F.%4@!'AE()E."?=:.E&C,FG,;00#A#$H$%27F<)4>&3;5E:4.8AH"/4,#4'H?><2H=?0?5669()GB"D5D(G65(60"))2BB*/&?*+++#)AB*
@r4198
NACGTTGCGCCGCCTCCTCCAGTACCGCGAANTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTNCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGANGCGTCAGCAGGGCATGATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTT
+
!'''+"'!$(#$%*&!(&*"*"("&&*&!*&+!'*(#""#&%)$&+#*%*'&)*+++'"*+)"$&""&)'!+#)&%"%'%%(($"$#$!#"&$#%!#''"*$$$*$')#*##'$$+*($$+*+(#'*(&$%(#''!#$#&$(%"&"))"()*((#)!#(!'++)+'$!#$%%*)($%#
@r4199
NCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGNGNTGAT
+
!4F)9</DA$7-"%+;8F>$@(#/+!+G>&B>A/?2G42:841(9+5$&AC%2B7""CC%H7:9:9?B%F!:3DBB
@r4200
ATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCT
+
H,4%B'5%D)<D"#,/%>F5+)D,+6%C1@>*>;7355>!#=)*)B4
@r4201
TGAGAATTTNTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCNCCATCTTGTCTGCGACAGATTCCTGGGATAA
+
*'&))&&)("(('!*+%'"(*#$+!$%(+"$*$(&(*$"#&(!)()*)$*%"'#))$%$+)%!'")#!%%+(%)'$)(%#%"!!'))"+()'!#!()#*#%+)&'+*$'#'$+%"$(%
@r4202
GCNGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCG
+
6,&'.B(G.*%5('#<*74<F+$8*D)<':H$G03*G=#,,693,&8(4(3%1?-
@r4203
AACTGGTTTTGCGCTTACCNCAACCAACAGGGGATTNGCTGCT
+
,;,2'/E9@G3=*8!!E0#D<$/6%?D0"$"6="DGF)#>G?9
@r4204
CAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTNTTGCTCCATTAGCCAGAGCANATATGCTNACGTCNTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCNTCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGATCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCATCCTGCTGGTTGACTGGCCTATTACCAC
+
"??>73029G+-'D.C(HF;))988GB'+6F'/)87BE9!8!@'('H/>!!,4))A!'?,&C'81G,:$B!;AHB6.$2-C#+2&/*$=@,E!C>6%%B)30A!1"$2+E,;,!0!<:=&.F=)$1-!>.:C%&&2G+:?$=F)%%F,/71H+,62CG%$'G5/-C=;@?:=D*(497F%8392"%+:)/<E!G6&)&+='24'B<E8F":C>9$7&$D5GF6F0.3D$/1;+/1$""D3BE$H*)->>+>G?&;>/'%&!>+8'",$E1!
@r4205
NCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCA
+
!8.4>=&"<:D.0F((5'F#*C1#;%A;D6;1-,@(26=B!"=:6$.%2A22=,E./"7540*?4"3::15D$)@3;AA!F2,/#0*
@r4206
AAATGCCACNGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCCGA
+
/51-$088-(7%:1)(+B!7)9A'"2B4*+7E,>%0$*+9;H;';CA)66;E-+-0)?CC&<E%4(F0)@-D&5<0*#4$1*6'+H-A(641@A@%4">0>1/6C,8&B7(@>"0(3?<CF8"('?:EF/01?*/'E>H8<401H48E+02F,?'7B-<C,?@*(9B=.&6"
@r4207
TTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTNTTTTACGGGATTT
+
>6<>,1%=2D60F-<:85C%A,%$?$H5?,8+G.01C&2C;>C:$0H5!D
@r4208
CGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTT
+
734HF!8A6B:/4>"7G77'191BDB>)+53%:,BH?D'3-
@r4209
ANNCNTGNNCAANCCTCGTATGACCCGACCGACNATATCGAAGGCTACGCGCTGAACGCCAGCGGTGTGNTGA
+
(!$)*(*%%#*#%#&!+#!!#*&#&((&)#**(!*)"&%#(%)('$*"+"$)'!)'$!"("#$%(%'!"*&$'
@r4210
CTNCNCAAGTCNNTAAAGGTNNNGGGNCNTNTTCCNGCNCNANNTTNNTNNNNNANCNTCGATAATTACNNTCNNNNCANTAAANNNNTNANCC
+
#""#"$!$#"$""##!!#!$$""!"#!!###"$"!"!#"!!"$#$$!!"""!#$$$#!##!##"$"$"""!!#!$$"$##$$!#!"###"$""$
@r4211
ATTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAACAATAACCCGCAGAAAAACNAAGCTCCAAGCTCAACAAAACTAAGGGCATAGANAATNACT
+
()+'+%)))%!'$'"%%&+%+())***!**''%$"((#+&)+*$#&#!!*!(*"+#(""$$"&#+)*%)(!$+%%)"'#!#"!)&**&!!'"$+(##("*$!#$!"%))"+(%&*"(%#*$#!"!'"*&&%)(+&%'$*#''!+%(("!$#))+*+"$('*&$("'#%(&'(*'#!%!+&&!(+!##+#$+(&(*)%%+*+&&&!+($'"')#$"!&%"+)&"#+#+'!$%
@r4212
GCTTGAAGTGACAAATTCTGGATACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGN
+
!;F2,5E2D>3-=8+*<+!B<B/2@<228F*8,6*34!1&E?.=#,9,G4E1/1GG'&-&E-4;?#<?B,.C:0%#HG:'7EF(#,H:@;)HC;;53FH<=6BH)C(3F*C/(FC5G>93
@r4213
NATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCTGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCNGTTGTGAATCTTCNTACACGGTGATNGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACNGTGGTGCTGTTACGTCTGGCTTTCAGNTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAA
+
&E+=#A&GC!3F#-!.),G(6#=1C*'=613??C5.9,=203'F$=,C1@"2&8<=:23%<1C)>5#'(#"D+#%$@-,>=F'(7++,C:7'1*B/>1+<F80.6,HD-%5)>89B5:+=&<"GBH9;H>28C&9$G?$B*F%A)A7/$-*9>!.4*,:H.&H5%521%C=5@;G;"4@9!1;"+D4B/"/3A6>"F/'7H#>'(6<5*!!+94=0=!2./?&39;6>0@'<'73+;>$-0*<?(+"07.H=5$</:<E(;77)8=!54B0AF9HFE'H?8')E(>@?'<($1A<DB?A?83H@G-;5%7F(5:9,B<>!,F676!C4F,8.4&HCA;E.(3(7-.B-/G844-1-!?E(@H9/:!'6+?&:B3=<:/;4$-3)E0%%H9G/#,.5FFE04#?A"B70;6&&3C?'>:;!*CH.>()<E-3670C.(@*FHH@%/2!>/.9H?/:1"@$(E4#4BAF%#)8E*H;1BDD(87716$CE*.9="@5H;!1%E'@+8#CD=%$$;H+:B
@r4214
CCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCNTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCT
+
=#+&'>!@07C&%+@10'#70=3E&"H60C68,53E!!!2HD'6/;;2%-7D5)#147BECG%+)40.>D:>%C9:F:79!61-"&/=,-=-987-6*G&F/>F81?-9%0.',>?&*8:D731"952%A,-7=?./%/2'3F8+-F8F$9'#F2.4@,:-D<&*/:0G>@BE)@%&3>HCB4"@8>98(=>/5FG%8H64<,+C3$&D..7G:-<729F-19E2"1>6BH:@AB*A<H#$A!B)<59,)<<,,3+'H07(2F(B%:!&!>;8&C!;@5":<)F#<!(D!+G-4.C/"++5H;.<+#@9=7'C,F4<:@(8$@F&,6'G47#0!;E81!G=D&;+0*,C=:*/,:"3!#)G4#/,B9/*!*>E#76CAEB?
@r4215
CTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGAT
+
8FD4#=3)H?F<4'=@C<#AC?:&8);)E??.6',E2H),-77A.0<G:F#>?F0?;8C5
@r4216
CGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCGGGCCAAACTCCGCGATAAGNGGACCAAACTCGAAA
+
(-',#?2/@>$1)0'F/8D<F7=,$1*=H?->5&/>9@H?8&,3),6;)%#$8$!.5@><&?G+<3=?>0&5@B!E>"7)/,
@r4217
NATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTG
+
!B!?%#:G(+1.*%E2*B/1.>AA+;F)81GDFC:@8D-/0=?8@
@r4218
GGAAAAAGGNCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCNGGAGCGCATGGCAGAACA
+
5/./C77/:*C-7B,'=,>0,-43F@H32F66<'=64=>/;1,D!?F$>+6;'BH6*:7!(6B?F608A+3B+773+4,%E9)ED1#B$9)3&F6<80)!*)@4HE-B8<F1-331?*0F(AB2&(G7
@r4219
TAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTGTTATANGGCCTTCAGCT
+
914G&-A7B!G:$7=+(6#+13*25<G!E-6;5"-8,.1*&;-"/3<E(76A(+;=D"4$*F;F0C?<B.A>"<1E!6-,088/,%4,0@8.CD8H=);26"
@r4220
GAAGNAATTNTTCCTGNNATNTAATNTANGAAANANGTCGATAAATGGGCAATACGAACGCCGGCNATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTG
+
$')#'#"%"%((()*)!"&)&'*'"!*#&$%*&"(#+$#)#)&)'$'$%%'(#!$()#)+!$#!)"%$!#&('!+!')&$'*&%+#&)*)(+$+!''!'#)&#)*+
@r4221
CACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGNAGAAATGATGTCAGGGTGATGGNATCCNTNGGNGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTANTAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATNCTTTATGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTT
+
E-H:.>A*G"A)'=='HGC2=4=&FGE34H)0#,4#?+7?979"@+!HF&>>E78GD#F35AD&6HF/:!(AGBB+8G<&!H0"7H=*F963:BFH*(=<F)-B!>H<24F,-#D9(2'0BD:2,GB%0"*/:7!)0H9,D>HG69*=69D$?"G96H9(=$9=+:G4E,23HE0@D/@6A721*6,9'*1,#&/A@#<DC,??8'$580:075@+G+/40F5>#"(5C-G4*@$8C+(2>&E3"&:"8,%=,AG:)+%:+(4:?5G22E>9?5<9$"
@r4222
GCTTTGATGTGCAACCGACGACGACCAGCGGCNNCANCATCACGCANAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGANCA
+
&#&+')'%+%+*&*!')(&)"%**$+!#&)#()+*)%)##&%(+%*!#*((&"$'++#*"!&+"#(!"!+!*'+'!+!'*"!&('!#$+$+*)(%%!#"#$*!
@r4223
CTGTTCAAACTCTGCGCTGAACTCAACACGCAGAATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTCATAAGNCGGCGTCCANAGAAACGATTTCCAGCCCCCGTGCTCTTCCAGANACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGT
+
G92%DB+%D)CG<#@"9*"A,A@HG3#A#&&?5/3$!1;7<.&6)!7)A>%(F(&-,"H46:)>(AF98<92';501=@522??GD<H*&8667(2E$6")(//4F@H!;:(>;+*&)D)-!=3;G1F@F5;-G)),7"$5"H=A2A6&.F$+C=..<:=)%6A#:5!"$='3,.?0&5D*BG#":,37,9'2CG,8C#2
@r4224
CGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAA
+
=;=!G3-::4:"B=C$10'@+5D$F/>+!-,#<!'46A+A1.AF@A$HE
@r4225
AGGAACAGGATGGAATTAAGTCACACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGNCGCGGGTGCT
+
3%<FFE,##22?'HE5"%;4.166!7&6+(=CG@7C#9@*9A%8);57C-40$84,"0/39=F>8A?BC<7,"EE"4H>01&50AB*)..14E!:-:E1-'-1;0'+D?&*G21;7,8$)617"/G1AE>G-:'3@=0.%C$@3HDE8(0$)<@!342,<B6@!"F/-=7(+3E:%F?H$&,=-1"D%DC;
@r4226
CTGTCTTGGTTTGCCCNAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGT
+
=?=5":>&#G8!AC!013:3@'=0F9-)-"C>>A5D2B&>8354!$8:@@:8$)2':&5*E5<+-%0F$4/=F67'*2*@3/G6F:H%"60)$A&@E+G-
@r4227
CATGTGGGCTGTCAAAATTGAGCAGACNAAAGACGGCAAACATTATGTCGCGGGTATTGGGCTCAGCATGGAGGACNCGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACNCGGCA
+
*8%',6&+=4&((H4-GG0%4%?C21*?40F+&!*;?7CG;"?(;81/,001.8H3%4G<@C%-1?G.60';6#"8803E7H<FD?)+>$$ED,EDC%%1G383"14?.2E7H-8<;;6$"C64=/!B87*A(B32
@r4228
TCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGG
+
()5E-+5,>=@$1(<"?H4BH"&4FGF.?G8;"=))>*0/9H.'025&0#H(;G@3'=6!5D-?,7@3-/C8"E#G
@r4229
CNCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCAT
+
)'93-C$%%6D4'58,4DE*-D?"5)"53/#F607(*04F>$=.C/6D/
@r4230
AAAGAGAGTCAGAAGCCGNGGCCCGTGGTGAGTCGCTCAT
+
*)'&)+#+'!%")"()!$)&+%&")(("#(&!$+&"&!""
@r4231
TGGAAATGGTCAGGAAGGATGGCCTCCAATGGANGGTAGCGAAGGAAT
+
,8H@2(0EB?.<D:/#.0'.0E"--4.A(F&)955/2$>8$G/')23/
@r4232
TGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCT
+
.!4#8,G*D><(1@;E&+=<G1@3?F?8A%,!2E+<"),G'DA+/"D/07G7&&9H-E@H+F?D7G547@44*8D64F49/>6E11'7502CE6-G@C+%%%#
@r4233
ATACCGGGGTTGCTGAGTGAATATATCGAAGAGTCAGGTTAACAGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACGGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATA
+
E!"?2;5'2"#%F4;<F<":('2&D0=8)H@#D@9F<35/E6!46EH+H(GF+-9!2$+':A*+G7#);:&H8.H/#30$=0!;3.EH2"2H#H%!G""9>=2933-H.:2/A$/#C==F1'E(A!0B9#F'/!!&2E#51#;)%07>*/:96
@r4234
NAGNCNCACNCTGACGCATCTGCATGTCNGTAATTGCCGCGTTCGCCAGCTTCAGTTCT
+
###*'$(*'#&+(%+%$*#&)$')%'"")!*!)&!#+%""%!$(*'+(+%%&$&(!#$)
@r4235
GACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTG
+
+'&&&%$+%()((%+))#*%)!')!"'"$!'+&'$$')$"
@r4236
NGGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAA
+
!!HB@3='9/-=HG%&!B%@'3H?*G:1G&/G7-&>0,GEC6%&<<?,&#G#=A=!!<F$%;%EB,F94.:"G=#H-*$C(%"AB+&5G2+*,2*(9/:D%?ED&##',-D
@r4237
GGTCAGAGAGATTGATGTATGAGCAGATTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATG
+
.@%=0=FF+&FA>:A0<F&-2*?2,>%&+*1&6D.E?B0=/<4-)44E7#$,B.%7$+H7!:2!1=:*'7?;3?43&4')
@r4238
NATATAAAAGTAATAATAATGGCCCGGTTTGATANTGATACTG
+
$6#=#<GH9(12#6A);4.4,D&:G-F6*=$/4+H%+.(,.7)
@r4239
ACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCATCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACANGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTACCGACATAACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAANACAAACTCACCACGGTGAACAATCCCCGCTGGCTCAT
+
G64(-F(;=EH4::*&D5")E1.$D3;&#H$5A?%<)?"92@7?!*;<$;?4$<,#'&G9"7&!D%/.9A=F26G8GFC%6)F2C11C57>)=*"*<@:<#-.$1A0,;%;5%2H6>>%#04%&%-:>'"9$="8#4!/19>:.=H"F8@/GH?+D90'%)&#HG(6*'"H:?&@?@GF'9*!ABE5?2:0H?=">"$$9%!<2=+*'E.!>?G5:<?)<:9B28+06,0BEBC4=8C("(E-DB%F"&,)%!1;#@G@='D+A&>F6"$=CAG9/C1=F!72#1/0,(AE0&?3340+1!"A62'D&+#)"FHC3E(53)G--2;2H%4-B5D-=:*<138E'"31;47B*8-.$*'1G(<=<*D%:+E>0F0+<<@9D
@r4240
CGNCTTNCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGAAGGCGAACGAAGTGATCACCCGCANGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGANCACCACGCTGACCGTGGTCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTG
+
*'!**$#'+#!(*'$+!'*'")'(%*#*%&#'$($!+&*&+$)%#("+(!+!#"*('!$$(#+&(&"(%&"")!&*!&*$$$#(('!"&"(!)*"&+"*$+!'++'%'!$)&+*(#)+%&+"'&$$#&++)#(*"'!("$'$!+!$+"&#)!&()!"##%""'&!&!+"&+&"*%+!)**$")%&(#$$)+''(!!#"%%)(!"(''$(*(''*&+#)%++""+)(+##(#%+'+))&)$$&&$'+'%%%$)(%!!'$%%*)"&+&*&#
@r4241
TGTTCTGAATGCTCTTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAANTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTNTCTTGAGNATTTAACATTTACNACCTTTT
+
):=5<04=<EH8%><3=)4'%C<*)7.=F"H;991,'"#F!D4#2$/>*?$FG(@F+9=/28!-2/96:%&7?&"@("(31;)+@-7@7=<;26>(.H,2*E'A)<:-/D@45A5A$*'E(+D!>F,<"%CHH1=&2;03A"#9$/94B.:7H9C)%6#0>9"'?F)-;.8!)D@'3$"@G30)'1"-BCA!G0$+2(/(44&
@r4242
NTCAGTANGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCA
+
"<98E"269=9H%!;#6!D-@G*&@%>&)'@0<@-;<?0E1;0F'A
@r4243
CCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTNTGCCCTTAAAGGTGATGTCTTTTTCCGT
+
+39.=1%?&9+'A<?;,-15<(49;6A"%:A,E?'&G?DGB48<C67=4HCFA(=!@%>C..&GE29CC10.#B(G:>!12F>%GCF73G49*@(E
@r4244
TTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATAC
+
C8'0B8!CAH;"B,%<<9/)7%5)/2)E?457+0+7'(<F?6G42?HG62;"<:?.4.,'H,0C&!""08DFH2*H(E#:@!A6$%!H*')!F=(8':$:A&;*!:35!E,7(A40G2C3#<7'+=!4GD0+A7=->;@0D-'1F7
@r4245
CGACGAGAACATCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAG
+
7:H//9@D(-/<C98D3#HA9A&=EA6"E8@=4@F)4$(70>G'8-&803E'
@r4246
CGAAACGCACCAGAAATAAACCCAAGNCAATCCCAAAAGAATCTGACGTAAAAACCTTCACCTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGANGTCGTGCGAGGAANA
+
:G&F.8+77<F@$8E688EB>(C.0/B):D<$G#"'+E'"0;8"62$',7#30?B,C>6F%:!1497/2"*1D;-??3G!4'"+=B?BG@9DE/.594E5)"$>%:D3,;!.)=
@r4247
AAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTAC
+
0.&1=**<0?>?:B$2&"+EC0*/)!96'9-@8AH/6></(H?2A1FGDF%4!?7)D;!E:6>=0"H;<!H#6:
@r4248
ANNACNCNCNCATNNCNAGCTNATCNATANNTNCNGCGTANGGGNATCGGNGCCGNNTNTAGA
+
$!!#$#$"""$!$!"!!$"!$#$!$!"$#!"!"$!#"#$#""""""#$#$#!!$!!$$####!
@r4249
GAGGNTTAAGNAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTT
+
)$)'"*)&*%!+")!(!*#$$'&#)&)%&$!*%)!#+)))))'**'!+*+!&+!'++'"$!""++*'"%*("&!$!%%($'$%)'
@r4250
CNACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATNGAGCCACTGATGAGGGGAACCACCAAAGACGATGTTATNCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTAACTGTATTTGGCGATANA
+
$!@-410&3C04?6?E3=6F1),(12"@<9+)"6>65!8!1G>%=G#H(8&'5/2GHF9A9#%#+CF1B:&6D(!#.6B2;@"4+%4B7(!0F"1%&)F4!=:,&<&BC>;=F6729G@)&78H*D/0:=14G;C*6/5G:'?.>$)(H)8460=D%=9<87%G.B1)9#>743,$E44
@r4251
CGCCNCCAGTCATCCTCACGATGACAGTCCGGCATCTCAATCCCCGCCAGATGATAANCATCCCGGAACAGTGTGNAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGCG
+
5CH0>"*20.H-3)"2=G<6<"H%*(,<&:+%+!G3E</@?&@B?"81%4E-(1G"G6*55<4?$,*#><%<$H*&<8F;7#B*-5%9"F;'##&;+"?FC2?;4;(7#,"=A/1DA+'>$
@r4252
GTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTC
+
F2"D,&:EAF5*/.4<<"0*GE*FE'8'6;!%8');5##*/2?0#42:41F@D7F#8;H)H4:*5*G?">+1D
@r4253
GACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCG
+
1%(1+G&3423F203)9#?.!.5<2!046C1"(C&<E<4F
@r4254
GCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGANAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACG
+
HA%$!-38*64:"#A1?.*==<C<1DG4G@C.8E&FH-B@B$F"/G):*?D??*<9D)5A+(!08>57H+G=9&&=6H:;7D#.8=2H5-H56EG-3#-B=2+4(,"C=B.93?8&B.1GB;F#*F$E:4*!(!*26B'@:$@@*%2C5BC)"/)?&)C/64B@C?@4$<1!'E+!@$-=0G4,*FGB*7"$'$!/C:11;B1..,0$.B3
@r4255
GACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAG
+
:%22>?,4+,.!E(-..0)D15E&?-#:9A>%44!-$9E':BH!<G$0?9H8B=A">!H-:2CFBG(/B40<F0:H63A,*$3:G1999:%0C
@r4256
GGACATCGGNAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTNGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCNACGAAGTCTCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAG
+
+*($)$!(+(#"%%')%*'!&%)$*%!'$%(!')%#('%%)')&#+!*)#%$(*$+#!*+#&!#++")"%$(&$+##"#&'$'''#*')+*(+*$!#"("+()!''&&'&##)'"&"##%(&#&$%$((#)!+%$%*&$')+$*'!"("(*"'*$+$+""'")))$*(+(&+(%$))&$("'&%%+'+!+&"'##+($"+&&*($*!))$+#+#)$'*)(*(&&*#)")"&+'(+#$*&'')&'&'(&&+!*%*!&*$&#+#""$(*%"#)$!(&")""'(&"!!!'++$(!)%!'%&%+%$("'%&)+)+&#+&**&*"*!&%*%(*)&#"!$))*)("'%*%+&&#%"+**)!#!)%'('!"&)#+$)&"'$+')%'(+!*!!%#+*$%$+(!$!+(%%(!*#")&#"&(!$%"""%*)*('+#!
@r4257
GGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATNAACAGAGGAGGAGA
+
8&./"%)7%/?7;@G@7+$*,H96D60G"BB<*?9BD<==:6$*!>&>!7$=6,>;H#<-5<-'&A6654"#+DA"<)=HCEF;B3::)<,!(8C"9<8?(+5;36/8,(1D;5.#4H=%$"'<;19A!G320+"!*B9*D9@31A22A/.6!'>:"B&C"=9:)1)2F
@r4258
CAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGGGCGATTATTTCAC
+
4&0.;=49#/5!3)B3('AC$+.2E</B;E*=@"F+.4'7".2G(*575B=AG$7B6"!(95;>30$AG75$@@/00BF?(%:F'(/5?=&!>@0&<71"4
@r4259
TGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGG
+
"A9H--9>3!3?:3A7"+A#(E-6631FHB074H5>$,,7'20/8"70=C=F*CF/?/6?A3$2F).:C:3(6%2=8>(&=E*;$>&:4<@512"&=C'A/!77<EE'E+,HA2G!>11A0&/E3('%?#F6<4D%6#/$2!$.G>+?'A581HB+%4*4H:3-
@r4260
CATTGTGAAGNCGATGTATGCCGCCANTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTT
+
:70D5F8,E=?,-B0$2@=B(D(C#)E>A5>.G6-+;C<E);H-H%%<+432EDB?'8%B4C"D<@/
@r4261
CTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCNATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATC
+
?)G4)4!7=:/F+-)@>*3(%HF&7D:5?%%9D-$@CF%"F=<*.?/HA&FG=;H!/321>A:(%:6#77+<A'>9*(&">6.(D2H
@r4262
TCTTTTTCTGCTCTGACATGACGTTATTCAGAGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTNCCGTGGC
+
*E?'/0:&@35,.AD.!-145H*9.-$#/F8E6)!C1=B77;)%*(&E4+#D90H,3(AG#1%":@>:$7*#3@)'2C2
@r4263
GCGTGATGGTGGCCTGTTCTCCGGAGGTGGACGATGAAGACCTTCCGCTGG
+
1"(69H07E"E1(%G%7#>!9--12H.*D9DH*,575:?>:/A!52D241<
@r4264
TGGTGTCTGTGGGATATGCTGACCCATACGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTNTGTCAN
+
(H<@!C:94%8?!,/HE@+1:D!?'8A32)C61!+>(2/"5D(DB*@D8H<*'-004=8330"!!*GA)2A.62120F1$>G"@C$0#:"#4
@r4265
CGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTT
+
$A<$.>4%@HE#ACF6'1D0<C,/)0&-H$C8?/BA"DD5@!9@$
@r4266
CGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCAT
+
GF(8/+HE8423H!1D6@F,3/!;)&)?:'&CD@)4.6>+"#/-2B'F&$9E*;$7#
@r4267
NNTCGCNCNAGNTAAGACNTGGGATGAAGACTTATTGCCGCTCTGTTCC
+
"*%%*(!$("##$)%&'(!(()$&+"$"")*%#"&'*")*%+(")!&&!
@r4268
NTTATGTGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAA
+
(+*&*"&!'$(%!*#(!'%%(!'+!(+$'$$%$%)%$"&(*(!%'!&$)'+#+*%
@r4269
AGATACCAGCTTCACTCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTTGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGNT
+
((+#$(&""*+)*(!!%$)))'#'*++""')$*))#"*(!(*%*!%#'(!'+$($#)(!'+#$+()(*!$$*%''&*&+##)(+'("+%#$#'$$*$"#&*$!$&$+%'!"'&!#%$&%)#)*(')"+*)#%$($%!%)&&)%()"'$(+)&"%*(+"(
@r4270
NNTTACACATTCCAGCCCTGAAAATCAAGTTAAACCANACCTATGGTATATGCATTTATTTGCATACATTCAATCAATTGTTAT
+
'#%#*+'+!)&"&&""'%*&)*$+("#"+%"+!!'(*"+$""'+!")#")%%*#(%+)*'%'%*%$!'%'(#'(%+%(&(!%"$
@r4271
GATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTG
+
86*B&228H;@1A5E0AA5D+0FEE(C<"4,1=CA733=8>9A+8$?8D,,+;959C&8E;-=189=<4;10("*A3,@=(803=A(#'*
@r4272
ATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCNGANACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAN
+
<H0"6>H(A'.B,&%0>@B$*/FDFD7%7-=96'*)$EB#(F0H2?E=!@E?##F>4/'$$@G2<G!28,5)!)B2;!;/>#0?-$6:F"==31/03;):$10<8A@$"$$+6<C1A-/47(C<2#0HF(")"9$"HD0=5H+;(':*$*:,2H7H!,!);;4H?->F8+%7=46DD,*9=#;=5@#-!.#4&
@r4273
GGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGT
+
946%8E4"7&<1=?H9H6%)&$F*><1)?A=!&8C@=873<:?&*$EA+B!9F#
@r4274
CGTCAGGCGGTACAGCCATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGNTTTACGGGAACCGGCGGCAANTATGAGCCNGNGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACAAGCCGGATTGG
+
1"D5*+,HC#B9*=*HF,7(40,8'(HF>:6:*E&A2,DE*CF(+1*GF="?<F!<:%DG)#147'"D">(.<,G!=77;'C33&829>%&,04(%BB@A!EC5E?G6A33&?C.)54,#=>?3C'18D0<F&$(A)-%/A"GC>."$
@r4275
GCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAANCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTC
+
1D409>;B88F!2%E(+50,%.=6H-6;=@?#6'?5<B8%7672G64C>7")3#,3E;3&+F':?/5GC<)B&G)/&$+D(=H37''A;E>GAD(9F?B;E?+5D>?H%11+D88=AH8'7&61
@r4276
AGAGTTGTCTTTTTCTATCTACTNTCATACAACCAATAAATGCTGAAATNAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTNAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCC
+
B0FFB!&%34=@4EFA'(=+>!/&45A!":!G!31?6;9<:)EC+/<%?+@#3;C2*G33/2;3AF"9/>E147H=A3F6=&6?C):0"!&F876*--G-H9==;#!3%DHDB()'47>3F@'61"D4+8+H=)14;(B&HA/<%@8(."=1F2/087)7:"7=31D+7+"(71%--C'*F$A-G:!8?3E-?5"G7*H2D=5-"3,"5<0D*(&
@r4277
GTTAATGGTTTCTTTTTTGTGCTCATANGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGG
+
;!8G=#C2=D:CF'"64*&(--'<8*!))-+7#8,!"?8.?74&09:#-3!8#',6:A(:$-&*@!/ED)097$7G88'#%3;0H('GE%*.7/?H>.(&F@:5:1!>B;7#?/;>5!466'G:2!D-$$':4G+$.75&)4#?H<F7A4.-1;,-9A86-&6!@(&4-C
@r4278
CNGNNCAGNNCCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCG
+
(!)!"%*%%#'!+!*"&'(!)*("+*''#+**&(&+$!!$)'%&))%*!)%(++%)('!%!$''($'(*')*$!"'!&')!*%+""!%#((#(+$&(&"!
@r4279
CCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTAT
+
?GG3(1#F50)=$((%?5#A-=(A5!A:,*2!4>,!91<:F73=!"#G;4-H>+
@r4280
TTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCG
+
2+,6@9G./89@6ECC<B2%)8A761>.C<:<19E."=8&
@r4281
GCTTTATTACCATCCTCAGTTGATGCTGCAGCGCNTAGCCCAGCTCTTTCGGAAGACGTTCACGCCNTATCCGCTCAATANTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACAT
+
F+$:;FA/0:#%"E&/D.%(8%*8>$@*=*G&F:<9CA6-/-$/G2)72&#@!@:2<,#=/4)0>+-D766G)A3F-C2%;->CE7?649@(=>%"HD%;(525B/)'9):BC930.$,6C763DGH(35@"@
@r4282
CAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGA
+
22456")+!9,5<7H.+!,C#@-,7B)?9;():"=2,E!@&12:
@r4283
CTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAG
+
)9E9E72*BEBE:5$H6-80F$**5%''B"'?-+3H'-A%/-!=#$F(B.A:$:
@r4284
TGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGGCAAGAATCCCAAAGGGATATTTTCGA
+
0.A%+.5F*3;(+3/@0B,45@B3!!.<=%-7$-@+97H.-;*6-=4F+;(8%?C>B&;G+H#7#"9,#/&2E5"/3G(!)9)?91B<3"'A)6(=("'@G5;9$B*#.5)D;"AG@?2.=(2.>"?
@r4285
TGCNNTNTTNCATTAACCCNTGAACTGTTGGTTAATACGCTTGAGGGNGAATGCGAATAATAAAAAAGGAGCCT
+
**$!!!!%')''"%'('%'$+!('+)(+#(''#$"&%*+'!*%)*%#%$"#(''#&*&+)")'%&%$!)!$%#%
@r4286
CGACNCGGCGAACCCNAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCG
+
1"%/8GGG,?>E5F9=7%&A9"G38'2F>FD@*+/H;/9H/>)3&/,)'A!9(3F?1%=9?$7*DG8&').+)?&5C(4>/9:F9FG*4%DC=%5>1/3,.)2
@r4287
AACAGATACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGNCAAC
+
7(*9#))"3$/+8A*/2"0A%,/65HG),4E*7!5&D>*79C%#1$5*=4!@0):F6-<,*0)?'<D<='!8/#$HE>A9D;G?!!E&46@:D?F@;H&'9089>"#A-89B0'00%'*=@233G0=H8,;#9H>G1(:$&*,"&"$=64
@r4288
CACATCCTGTAATAAGCAGGGCCAGCGCAGTANCGAGTAGCATTTTNTTCATGGTGTTATTCCCGATGCTTTTTGAAGNTCGCAGAATCGTATGTGTAGAAAATNAAACAAACCCTAAACAATGAGTTGAAATTTCATATTNTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCAC
+
(+!:<F*:G3BC::1;573D#7EH*>@"G1+@DA$$"$$'%0.0?C39CA-<44/97@;+G>0)*C;2-&7+FAA3F77##)?+*!03;:/0+';$0=27#'*H,2$H1B#+74%5AA74#D19'5#BA0);)'41$9$:$8G*=D-$+F54*G-?+>;<9824!<;H:@6E'G9&H)<(CE391H364#!'<-<%@92;F)>@!>DH(
@r4289
AGCTTGGCCTGANAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCNGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGNCTGATTGCAAAATTCAAAGAAGCGGGC
+
=AGG!F).!3$D!9!17><A5A#&.-F?'>E'9@*591G0#)0HG8,4DE>,;-'-F2*7$B+076+1B@D1$1=$."@E,13HG3?#"$,*;D*<84,F"$96&)D><F*<3>G'93=-(?)>-E69%.&%H,B+F@(9;D-;+815H'),*2A)*46%C'9D,E&'95<:>'#1!<%2':707.1"9/6=%DD<8/%''0*(>=72C<#%
@r4290
CCNGCACTTCGTCAGCCTCGCGCCGGTTCGGCAGACTGAAATCCAGCNGATGCATATCCGGATNGCTGAAAANCAGGNTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGNTGCCAGTCGGCATACTCCGTGGATGAC
+
))!%!)'&'+%"'$"++$!%"(&&&'"''&+&*!*+)&#"$*"%&)((&)%%"+"#&$*$"%&"'%(%'#*%)%&%'*&($")!*'$"')$""+&*&"*'#&'#&$*&%(#&+)&!+"+#+!*)+"$('$$'('!)(&)")+&&*&!++")&($###)!$+$&*&"*$"#"("#($)$*((&
@r4291
GTACCCGGTTTCACTTGAAAATAGCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCANTACACACATNACGCATCGTTCACCTCTCACNGTTTTATAATA
+
@#:(&H,&:#5=+./15A1(2FG$42<<D%>2.?AD/B=0=63&0>+;??1D?<8,2"5A'/.>+6)$%4(.5@7FC433&<:>G-9!&@$EF9B3.<D<D0+#"1-*&7.,!BA?@A$"%&260*D(?67B8B44>A=/2@E:G;BB
@r4292
GTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCACTCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTC
+
>>,93($C1E*BA<09B1E5A*B)/6=E*3!E@6";A5@%FE2D+%%;5/)-*@"9('54:BA<?+&&F8$;!6#-AB8.BG40CE7.'$AF---F4H-FG8394F1BA2!343H:/7@01;1);1!'EF8%A*4-2AG0';%F',;.*&+=#HB<*(@6?&@9:B398CC7!.2')>.HBH,/*E76CC/>D;B7$?$8#G#508H#!G$"CE$D.@4A!,.@$>*&A5)6/*!?/FD2)/$$*'DDH;?2@643:3(CH69)+A&0(%3C?9)++:@7$+E)2&=6&0"4((:;/F5HF1$H;%-E03.->75;*3%6+=22$:+#-*9,*=70AD07!AF3'CH9#H<0?-<6:$?);8,.-12>-$.)"G#$55@!+2);,6B;G=<G8
@r4293
AACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACCG
+
@$=G:=A=$A(EDB5('?B!%7#:'D%?.;+1;)#"F4">6?5%4H%8<9!C50*49:(0<?<$2#GFD?#C))GF+4799DD8/):)3%"1)(&59%1>0>>A-C%94,9%.G>1>H))*C-'",
@r4294
NCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCA
+
*;5(&.@'4&/;*=D1+5/HE!=(CA)*G%1-&>;A3GG/@4,'G#%':#&%*D%#>6)1;7E66/**7)%>-/*-);&:%>"#2>6./72>0/<;8*.E+$)5-A-..H?9#H-&#,:5(-/?:1.@9%D5")+::=B:AC$+&%6C?E0)#247:,G;@*A66-5</-A%H:H3#*5'$6'3!<B#4,#D%4989;>
@r4295
GCTGGAGTACAAACGCCAGCTGGNTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGA
+
B8<,6+@'=<3*/!)E?F./.6A+@++">75-;HA88(4;A8$5'/>*-C3=?05+-43:E#AF:C.C,2A71>2)<&0:>46:8FD>'D@7@.*ED8%F1C-@2D<<GE:?EE+3$E7A,A$B#A3B@733%#
@r4296
CGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATAT
+
8E>6&//2-%F1%'-G+0E=?/H;%C>:%?+CH?337B$0&D9/F<?9+;1,/E?+
@r4297
ATTCTGCCAGGGCAGCAAAAACGTCCGANACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCC
+
F@@;28E<+%!$@%?"&;>%E&#/(>&997DC*//?998*G6,>.'>HD/.(:!.=(2%7;-1C'4,/1&>BBF-"A5(:?"8E&:<"5A-/1B/,C&$:.E>C&5=C21C/'@:%!$07,)'F3
@r4298
TGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAG
+
A/18;>'):/)<%"F?BB!>6>;6=AE8*-2(*H"0A')0'F3F$7#5!1*+!??6B!>'F=E(<FD7=.F4(5D(+#A7G,3;"6$
@r4299
TACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTNCCAGCAGTTCTGT
+
9;6/3&/6%#7;241*.?/&B#<7#D>)5?>C5)B0/,<0@@F,4@)56$29G'94/:A!22:G7D-5&%9/>4*24A;!1<3E3:'(9.GG1*58,?39-509(.
@r4300
AGCTGGATCTCAGTGGGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGC
+
('+%!(&%$%(**&''!!$$$"%*(#&'$"%()")&+$(+!&#&$"$&#$##
@r4301
NAGCGNTGCTGTCTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCAC
+
#)%%($'$+*"%*%"$)!+((+*)##%$#&$&''#%''%+$&!*#)(+)(+!!!
@r4302
TTNCNCNCNGNCATTNNAGCGANGCNNGAGTCTGGAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGACCAAAAA
+
'%('''%"!)%$*%)&!&#*($!%&($+!)'*&++'(&("(+#%#""+%$%)(!(&)+!&$!)(!)+'!)'"*%&$&("%#+()&!!%#$"#%'&*$'$")&'''+(&$'%$&'*)$""!&&%(#*('&$+*"*&&'"#(!&"(&""'$+(#)&+)&&"'%"&!!#)&"""$'#$))*$(&$(&
@r4303
CTCAANCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCC
+
A$"@BB(%#:/(#C9B##@?.B*9%5;$*..D-34*.FF#$5#<:0E=D@9,-:B+5<9?F?5@B9@*@F2
@r4304
ANCGCNGNGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCNCCGTCGGTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTA
+
)&&'*')!*%+$%($)#%)$++!)*+#(!"*&(+*%$$'"'%')!$#))*$&$#%!"'(&$$))$$))'!$)!#('"(&$&(&*$)#+(#!('"'&(!%!#$&)#"("'!+#"+!
@r4305
GCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCANGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCG
+
<@D3B6):&A!#+1//#=E3%5,*-%;9+!CB3$*D#3EDD/5@A#/ED4(B5=5E/F,'2#56D)<B4!<%,<%-=>#>FF?@9&292D4D)G%*5%?G>8+H852&HH'!3A80)"C@,>=%=<
@r4306
NAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGA
+
-ED+@",3%"@G=<!:=G#/HF$.;8F7!E5D1DA*?-6$E3.H2"4B,C-;@4="!G5%1=E8@5?8;%.F/E=/!;C'FCB7!+;,>
@r4307
ACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCGCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGANATGACGTTATNCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCNCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTT
+
=%22.+)'7>%,G14G&.499*>?.$:4,9CD#>$C7.#+0:@8:CD;HB:$#?%$?A+7+'D/?C:61+?EA>-EB5.:1@5)>.=9;B),#AF?>(*!2@;#7,81F8A;56==8=*2!:"A;H/B:G:<6D'@0/4!,#=87?8#;>8/F@2/<2.,(H&5(5>7#$(3(7=(*C;"
@r4308
TAAGGACGCTTTCATTTTCAATGTCGGCTAATNGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGAT
+
!(/()61B@43H+8($3878AGA;F=G3&A>=&.7.!.A(67">=0%#5-EFD"<,("?BE(-/%F7A!138,7-@5+=346D1.28!;F<+F>>@FHA'=&(-54&<
@r4309
TAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTT
+
9!6#B92E7@2)2>'%):/=./8?H/0EB/F6!+2;0$*;01:%'#
@r4310
CTGCCAGCGCCGTCAGTGTCGGATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCA
+
*4&*4:#1A;B26!87=<7@0%4HE2@94A8,<%;..>@)*C<2!!*9C3A;$)F95EG3C<=7$B=B
@r4311
ACACGCTCACCATAAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTNTGATGAACTTGCTGCTTTTGATGATGATATTGCACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGANAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTNTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGNTGACCC
+
7F$13&($-%2)'37!?'2D.F<FD4/,-6@7<$571G9#:F9!0D8#9&@&"@02".H%G@$46#B!'":,9#00<7B7?*$F3'),6!?>29E%&93"8H4#2$(G'%'A@.=#:ACB@7A=0G7G4G><-D5#$>>(0=C92.1*HF7F0&D.?4;)?.4%C63,'+E?3+#CE:A#14+>-4.4EC-8$GG3!+;1C5"4=.(!0!;D9'2B">';<%E%B6#4A*8-%1<(??B'F>18(7&!:H.DB#0,11EE8./!D:B')%D/@F:*+@.:;=/">4#%?"?28D75<,>D8<>8<0AEF/&)$*F=,2@0*,*.E:%/)@A!(/&4A-C""4;B'"H>H3G%(!C#>9+"+$5;@(C3>B(,?
@r4312
TGTTCGACGGTAAGNTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGACGTGCCATGCTTGCCGGGATGTCATCCACGGAG
+
<>@9#C-2,/70/27A64"<>:!!:648D.4DGA$72HD(!:>)+9,"%?-E0C21AC61A&<&5?.)DB=-A;?#-17/=?FF24C)#8%-E4E
@r4313
TTTAACCAGACCAGCGAGTCACTCAGCGCACAGGTTAAGGCGGGGGTAAGCGGTGA
+
=G1*%6=B&F=&F+.>*<D#-A:A8B%2-54=*;4H4HA-*6E%3)=+D+5H?,98
@r4314
ACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTC
+
G9($+>@B0H,=G89%971E7)/.&,;--)3'>0*#C>C>A?;-532C'2.3HE7A#?1G<32->.)5:>+9%7824<=@>=!&$30%-H.;</)"21)5*0@D!/FB8*"=%2*;'40>E/5G1H269'%<27+1&:5@$"GE9)C+:/A/+G1>;#2@&(@59%+$%G6&?.35;+0
@r4315
TGTGAATCCCATCAGCGTTACNGTTTCGCGGNGCTTCTTCAGTACGCTACGGCAAA
+
%'"*+""&$&$"&')!!'&)#%")+&)#!)#"'"$'%(+%!!&&++)&)"+*#('!
@r4316
AATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGNAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGNTGNAGAGATTGAGCCACCTGACAGGGCAC
+
.G-;3/4+A;4%,'F"(.E>!E(8=(16A19$"'>+C")3G5,A)(6"G31/"1CH68,7F4#F/$;4)=%H9FAB4+G3#C%((C!0HF424">(1$-?""=<%BB::(G"*6FBCA-A6@?0<2.D)0>0&E?3,<7B+:'"@C0%.$59<-<@CB&<&44B=GED+->1)'')5+6=8:'FBB
@r4317
GCAAAACGCAGGGCCGCCATTGATGCGAAAAGCNGGGGGCTGACTGAC
+
GE:>'1B<01'>8;=93-/#,$EEB-B>D#)@D3/C6(8=85,83GF8
@r4318
ACAGACGNAGAATTTCATACGTTAGCCGCATCCCTTTCACAACANCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAG
+
:(5C<'%,=5$7**72.>8A9:%G0'0'+0+(!B;"HH7B9<H'.>#C?,=G?)!C6!@/,:1$<-80=9C$4<)5'D)%.08+6;</*"
@r4319
TCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTNGCATCTTAATGC
+
AH8*7;D,5:>;A)4'-5E";'=&'(H20:;'/E8>0C-BE&GG4;)"FD>0H5;*/6%+B#A*9F!92A+HA(."0-21(C(02BG4=='#4'++
@r4320
GTACTTTCAGATAACACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAA
+
6)/4.(>D>>)(A-!4#")7@FA@7=>?:/6%?!B7>2H*5'5;$4B)*--/&%C!>#C38"9131"0;=?#*D0:3%2++79$13!8GF.;*C.=F,4
@r4321
TGNCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATC
+
=+B8H=7#4><84EH96%9(G)9,(!7/C*5CA(/.(3-22
@r4322
GGGANNNANAGTTCTGGCTGGAGTCAGTATGNAACANCAACCATTACAGGAAGTTTATCCACAGTTAAAGG
+
(&!("(%*!+)'*$')(+'*)#%!#"$+$+$")"&+'!!!'+"&!!&$*#++#*$()!(!#%++!+"%(#%
@r4323
CTGNATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTNAGACATTCGGTGAGAACTTAGGTGTTTTA
+
83@DD'.))2-?/:3'H>A:$A)48G9D=,9;>@2$>#@C"A:?.,:C)G3.EFGB$)824B@'(;D4=B0A40B2./9"09*B8A14%1%):53-BA*0<H47*$,0.,6),@:&G/6;+4?-$3A'%8<F4*!*53(9964,62H!967F,EG#A&D02G;C*CDD@)%F?.?4*=;?58+1E2'4(&01/&/=.1&BD>'0B@$
@r4324
AAGTTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACTATCCGCAGAAGACGCAGATGCCGTCCNTGAATGAAGCCGTTAAACAGAT
+
D3H.E0.+,*F#/.0/+3@DA;E&30EB=!=85>&'7E,/!@69G;-6,!'%0>!-4#8DH-'4*%933B@'$#8>)A$H/%9?134,!(143$18D0;A6DA(C4HH8G@"<.:6
@r4325
GTCTTTGGTNGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAAC
+
-6FB-'E8;'(2>1E4:74>;0:/.5,"7>*+3.*H/"2%@691"20C/5D-4G!#EA1+C%7,@;B%+>=1%#'#29A!!,;'ED<?.,9EB#H7A2:EB3!97#6E(03+6>H0E@B4E2DG>=@G2B1BD@!0"2C.7(C:/>@
@r4326
ACTATTATTTTAATACATAATGAATGATAATAATANTNTTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTC
+
*&'***862(=&C%,G+ED:-"7'81:(8@B<7A!4?!+%A2E=.2AC"4%G9ECG:H*40=229!+0$)47C@5;(
@r4327
GAACAGTATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCANCAAATCGACGAATAACA
+
7%&2-6F7+<=%/=)!E9-76'F2@.D$-@B%4;&E3*9CF9C'A5B8<2C=!7/0F05%80982$E!00+:5-2F7C*)5;++*<B/=;-:"'3HG<#%2;6?EA'7&/2$8AD&'$C:4<#.#',392275G!B"A@
@r4328
GCTGCCGCCATTGCCGGATCATTCTNTACCGCCGGAGCCACCCTT
+
?6H8$!775>B;7/:(@>B38B)E$=?*+?H2-;E+'1%:&:A89
@r4329
AGCCTNTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCT
+
AH!8G8#HE=,?+#3+$51A0&<-.8,'")66:E'D>?3?G/6E2/78C+13?3#/;!*G7:B"B2&*&#@.+@))DG'.>(#0.)'2#943>E)A=,7'%E2&:E%7(3@23!%/C*2&B+CB,<:H205F4(E*4+*D085>5G!$-#%C/AB3?&&C4$G'2B.%"8($+G$;=@5H401*,+-,D09)G%E@B3@:AAD#7,(4"!EG*C0G/*@7+'!5>/:?H+0G=)H+>>$82FC
@r4330
GGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATC
+
?+<?!-3D:,49846&&-%G>*#*$-4:?#%H!#F&!?31>;-?:+%9BB*
@r4331
NCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCNNGCGGATG
+
"#(("%+"!%()*!"**'*#%*#%)#*")+)##+"%+#)+("'!!"&(+'((*#')+$**$!+*
@r4332
GTCGTCCTGATACCNCGCAGGAGATGCTGATTAAGNCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGNAATCTGNGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTG
+
?>F&*;F1"!D6@<4;F%#2?#@!CH60,,?<005#,,G@0,4E#8*C#1/@#*8)%FAF:F!G4432&!>/*&C*H#-%!:C;61;GF%D<>-F.#!F8B:8;7!74C673B):4$/GH/8*#
@r4333
NCCCGNCNATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGANCCGGAGGCTATTNCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCANANCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCC
+
$$*(*%&&$))(+()!!!#+#$#!#!)$&"*$%!&+(+%#"!)#(*(()"'++&)*'"*%"&"'%("&(!"(#"'%#%+%))'+(()*$'$+**#&&$!)#$"$")')&'(*!#$*!)(%(&!+')+%!")("&!%#((*#%#)!("(#&&'*&$*+!%)+($%*#'$$)*$$+"*(!%&*"!'!'(+&##((!&$*''#*%"%"+*(+((+'!(""+*+*$&*+$&&#(%!&"(!)&
@r4334
TACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGG
+
AF1/7='=,@6":;(7>388EE6D2%?8>A<=.A@?;$;D%5&2A78+9=42>$&)+
@r4335
GATTTATGCTGGTTACTNTTGCGCCTGTTAGCGCGGCAAC
+
?':@'0353.6F..$B:G8%H3%&.$1%BD*5(?>3=:2E
@r4336
NGCCCCTGNACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCG
+
&A<.<8<&B"+@*$>05?:,,>HDB4<21.6:+(:F"!:G4E0DA0:8+8B&#2$!?618C?(E8*.<(:,1E6%74'.C822B49G,&=;0>=4E(97D=D981;$
@r4337
GTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTT
+
-D16;"6C+/F"F<.GG=5=,(/+-'.;;HDGF=65+500GC8-BF/C?22>H6-)@4C5$33/'#??=1>@>E(%4A='$?F!5!:/!CG#69F,B2;G>01=D6=4!G5B5)HA5H.E*(G%BBC7)?1?@8*$F$>)!5*E<83G9A!!9GA@->52@
@r4338
GAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGCAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGGTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTA
+
=-69?H8518>#1.B$EE%0?4C,6=8!2@&E(-5212@<G)&F-:!:-E<F8+"!F>1!EA"(@!EF>F5.EAG=9G,,<B5?>?4%!#'$0$GGA+)(5*00)A;*F%@(<(-)&5EF&D@?+&F'.*(B2B=.@%%02%0&ED)(F87!C;D,6?2#:@)$+"1.6*G(.137-AA16*9>4G((FG';G1(20F.*D$H>1D#9@(762".F=-<84'D9A0@+9,@&!H;%*F+#C3632A24;7HBH51%7+0G,)8#;.EB28)'A>(,-#3)*H%&@9C!<
@r4339
ATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATAAAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACT
+
/H$'**;>>>:4C,:GF(5>7.BH"8E1/F(H,H#A.;4@$=27465%-&,!=*7D5:'/-6//8:0A#=FCGF:.3>D#902.3/)&CD64;*"+5(;"5!9;=59HH&-,3$&E!22G81=#34--=7:&12FF7?5:A-4*522G2C4)GE/-(0*1C5C,
@r4340
TTTTGCATCGAGCGCAGCAACATCACGCNGACGCNTCTGCATTTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGAATTTTTGTCGCGCTGGGCTTTGTAGGTAA
+
$&;C),"38'H"@6/8BHD3HG33714;/(4>/*2??*+6>AH=*@B37"4"AC"-5D1&$8(8)<EH"+)'A<#/18":.@HE>E<;5(0#,'>CD<)29C=.5>C"6:
@r4341
NTCCNNTNAGNGTTACCGTTTCGCGGTGCTTCTTTAGTACTCTACGGCAAATGTCATCGACGTTTNTATCCGGAAACTGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCT
+
")'*%%&%'%+!&#'*#&)$)%!'"+"'#)")%$&(&+(*##&+%#$%"&*()+)**&%+%*%$")*&+))%)#'(!'&)%+$$%"#$)"($+$+$#&+"%&(&+'%+$&(&&""$"+*!"($*!)#'((*!#$!"*%%$!(
@r4342
CNGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGCCATC
+
+(''+%!$"%")%$(!(#$&&"&#*)$+'+*((##+"++$)!+!&&"*%$#*'$
@r4343
ATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGNGCAAAACT
+
33)9?514)16@6))D&7=!1+=--G*"&6C/3%070/A)-E,5.92B4$&6E??G2<E#:D(*'
@r4344
CGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGACAGTAGTGCGCGTTTGATTTCCACGGANAAGACTCCGNATCCGGATACAGGCCTCGCCGGCAATACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTTCCCGAAAAGCCAGAACCCACTGGCGACGGAT
+
(4%!B@.62:E&4,EEA&H)@,0HG*/!2,;90"4:&3)=%5=&?3!$AE4FH6#BG+907'**/5,<0;H=,FD2H5.1="9@:?96H;G*:6@%*.+.#""@<E5-4H=@*./-%:0>6"GG4#?3,7-850<!.#:7</4&#;&4FE)"?1-73H=;6&4H/@5;&.DH&60H$#;9*%)*$$72&&%AC#0$B5+)(?)D/+E&=))=97%C"4#C?9.G8)B!9@,<=E*8>370=47E?%>;9&"3-$5&5@>1G+90:-EE%0@0@-&!/1G:AC9'.@,,8<*!"/7*686?:B2."*$!C6CCA@-$-(:"A2(-:*E/;609+$,(!(5%5/3C'D/&B,7&EBA@*AA.""+",G?/8431%.-D;'3.04?B+6>0',H7<B")A7!#2%-%*C%:,(2EC3-"4!)7+9C5H"%5$(!(86<9('EED>(%6%*-/970C>FE"<6H
@r4345
CGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTG
+
)C:D:74*!198#2<"EB30GD*=51>)."0/@@6.B1H96!#
@r4346
GCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTG
+
G.B47(6(D;&,3-=$H(')&>)/"+('@*>4+73@5HA./2<"0!3
@r4347
GTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCNCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAANGACGACGGCACGTATGCCATCACCGCCGTGCAGCTTGTGNCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGATGTCACGCCGC
+
-5#5;6.G0+,%F$9G)H>G'?#C#+$4D&(1-;G'=A7&)-?,4:7!,)!<@,7?DH,2@F#&E6A;4?046?>'/16HB@;1+@GCA5:1@-.;41E!'(+6.*!55D9!%4G9?(7"#;*-!?-98;/528(7(%/;1<=*FD5H'4/7?946+/-0)1>AED!@)<&@9C:?:&>-C,DF);E+;60CG>H"6$9F0C?+%$0%'<1@=
@r4348
GATTTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGAT
+
E+H@'>9H552%E7;+859)'$>)8E(!A5:7@9/8##0<<45H4F$";6#5E!..*E9E@#;4#<=?G
@r4349
TCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAANTANCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGNCATGGGATTTACTGCG
+
D;"0;8?$26"'30;-C8=$8!,'@,*5D1-@(H0*A!.@8+%;77(>%16">!)8/$/"6C%9A)B'F,0C7=-!)-"0.7D**.,&@*>(19;DFA&A3)<9>,>1+$G1)+;"$9-=),=";'>3+F=(9?4/<6$:(H+<H'.7?;A5'385$(')3E,-2?@&/?G*'*?5<"!@'5263.A
@r4350
GATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACG
+
=C$5-'9A?@0*FHB+-34*FE8<$9-=E<7G%E==0;#E2>&(&.300F(9=#<C-:8H-,&-.)H<@7:-.?*95,<3)B<50>F
@r4351
TTCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCG
+
""4%(B:C-F":203D%"=4(:&89*4)93;3&"H-1#8B#$;?@3
@r4352
TGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGA
+
*4=6)%,">.;0#88F'.&08-3&6.A#14.4?5<52-#41B+5D3%5'-"9CD$,BC
@r4353
GTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCA
+
;%4<%3?:&0&)/72+A465,"!(,?+<40@(7;9/$>7?7@DB1$$%:
@r4354
GCCANCCTNAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTG
+
",-6<7:85?<67$G,FFB3@D*@?6+5&"3GD39>*68;E$-
@r4355
AAACTACCTCTTCCAGCNAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCNCGACAGGTCAGTTATTTA
+
-A#7+6H+30>++F71(0)*$!A3!!G%>!96)('!=,)@6:'6FD-028$C,%EE@=%,,("&(=01$1,?(A#DB-5E<&B??A:(/+G$D1:0%;09F;",-)@50AE&70E9-<)DH=$,?E&3#1H?49B#+G3>!!<$'%)GG(,HF+"86<9=
@r4356
AATACAGGGAAAATNTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGNTATTACTATACCTTTGATAATTCATTACTAAGAGCATTCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTNCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGG
+
36F<'!!2:<DH"B?=129$#?',*)H;&&?&'>>%G&%CF*4'H9>8'57-$E>&@;!8"(?==1%@>'<<"9+0B"&DB$'.-?A*CH>>H!:E>1D>=:&8%7(<+?3@=8#HGEB3#7#(13,2!76-*#C3F7<.3+2307<.=#8F45@F3%,2G(.0(4AD0$4)0%%#H1")"'H"F3!!,'%&.A0/&/D/-A@#$-8>A47FA(!',/>G0@%0'6D>E(#'9+3'1F(+452<2>4:F@'GE:'+H6*0?27G""2*:=G91$FFB2+.-7!4;("
@r4357
AAATCANTAGNCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTATGA
+
?0'+D6&+63;4;&4A7-9586>"-$%)*694=:"$D(A1%7FBB334C,(?3!&
@r4358
TTGTCNGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACNGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGNAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAA
+
D"/,!;=<94$!9<9?55;H4@)??A5+4+.?64G,$=(D8"E/<BGG7##-"4"E*<8(9)A2#/5D<0-G%-18F'2$03!F7&B<+2F?%B,.A<'+?*',D"4+;26C(9%,C9;%<!=(FDF*+(@",!6'5G>!C5"?9B:>DF3<G,9.*("#!F'&4H47,/@0=9B$./<'%@1673@$C.-57(FE1+/FB2,#CB!!43;=:9*C'8.:EG18%6$"F-F&-$5%C&<H?:'HFDD?>E
@r4359
NCCNNTNTGTCCTNANNGATTCNGNCNNGNTCANNNAGTTGGNAAGTNNGNNNANNNNTACATNATGCNNNCNANNNNANNNANCATGAGNCNNTNCGAANCNTGTGNGNNNGGNTNNNNNNAAGNCNCATNATNGGNNNTGNGNNGANCGACGNCNNTGTNAGCNNNCNGNNGT
+
#""#"#"#$""#!"$!$"#####$!"$"$##$##$!$!#"$!$#!!$!!$!"#""##"$"$"$!!!$#!$"!"!!!!!$$#$""!$##""!"""""#"$#$""$##$$"#$"#$#$!!!$$#$#"$$$#$"!""!$"!$$""#"!"""!!"""#!##!#"$""$"!"!$"$!##!
@r4360
NCCCAGAAGTATNNNGATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTAGGTTTCTGTTTTAACAAC
+
$&$(&&'!"($'"!"'&#+$!(+$!#+!%%%#*!(#)"&'"))&%&&&+('"!%'$$""%!$$****'&)$$*+'!"(#%*!$+'&$!('"("&&$+"(&")$#+%#"*()#&%&&%!!)((#&$%'!!!+*%*%(&#)'"+*!"$''*+$$*%&(*($&!)*#&)"+")
@r4361
TTATGTGAGCGTGATGGCCGGACCGGATTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCAC
+
=,2:.95($0?1A&'-@'1@=.B;6<EH<6;75-=;=6C?(H!1;BA@FB%B-&;:A*5""9.4(F;096B&6&G::A)
@r4362
CGTGAAATCACGCTGCCATCCTCCGGTACCGCGNTGATAAGCCTGGTTGACGGAAGTGGCANTNCGGTCAGCGTGGA
+
+6H>6AB>A)DH?G<0=.29)(#+:H<@)6(/)=2*$%"<7C):6!HE;=>8&C7++)@63<@7::9;F(:B4-)5@
@r4363
CGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAG
+
*4?/G0-:?>#7@"/C.AE8E4?&-5@!+=#>E=62G.B41-<>HDF42
@r4364
CGGTCACCTGGCAGGGGCGACAGTATCAGCCNTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGNGCCCCACGCTGACG
+
+&+"!#+"!'!+*+%#"!"+&$)+#$&!'")&)'%'&#"$)($)%*!%)%+)$)+)#&''%&!&(*$&%!#)$%"&&)'*$*%+'%%('&+*#+)++!
@r4365
TNACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACAC
+
#)9($2=):?"%;-905=HA%<A!59:*5.=EC>DD%'31?4<-'-8,//F:7)-%;8.AGF$7::A()!01$A30+?$%E::',G4-0;;=2A9?H.*>A$$@A8F#A#15-@2,96G@B8F8@1E
@r4366
TCATGCCATNAANGGTNTCACGGATANGCACNTTGCGGAAAATTNGCTGGCGCAGCGTCG
+
"$!!**&('!&$)#!)#%#"&&)'*$"')**((%%())%%*("*%+&(*&+#%('#'(%*
@r4367
TNTNTCNNATTCCGTATCCNTCACCCAGGCTGTGCCGTTCCACTTCTGAT
+
$&%(*&%$!)&&+#&('('++&)'(&!''##%%%%&'##%!%++$%""%*
@r4368
TGCTCGACACGCTGCAGAACACGCACCTGCAGAGCGCCATTGTGAAGGCGATGTATG
+
8FC.B3!(0G(20G$BB/A"0$@H23&7!.5<H,<='!F=D3&#<;'DF.'$0@D#C
@r4369
AATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAANATGTTGTCTGCGATTGANTCTTCTTTGTGGCATTGCACCACCAGAGCNTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCNTAGCANCGTCACA
+
+!CC6$=/"*=B/<"*&;(4*;H/'?==++A%5<0&G%!%D'%9C/B#)@/.36$4B5#=!-2-4CHD6D;50?&(2F">C8B#2*"(E.#G>=!'BA=";?*/!1"F=G5$C<B::AA2*"3F1C%<CC$/5>,/:1;FAG<4&28>0$HD3"$!?$/+#2-A9@!(G
@r4370
CCACAACGGAACAACTCTCATTGCATGGGATCATTGGGCACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAA
+
4G)?/?*8;%)=(4D!+B2<;71>%:&5E<(%@?/"*<11$B.4&#B24*CF":&5=EE?66D3/6;DB14F7C,-)82!$2"*@-2(/"+F'B">DH!9H$;E)%/+:6&1#5GFH3,D+4?H0*CH4,A>G,5#6!EA5@(;H?57AE#*3;G8,C819*,-1@!?!5!9<1>9!)9(:B$1?#.-$5
@r4371
CAATCAGCATCCTTTACCCTTCATCACTAAAGGCCGGCTGTGCG
+
<,A6F7H+;(4>>#:-D/&C"%95C,$,;'0(C=/:C=F:)?$/
@r4372
TTTAANGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGNAAATCGAATGGTTGTTGCTNCCACCATGCGAGGATANCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTNTAATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTTGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATAT
+
+"G6)%C3>C'/),!!,4?)@1FA(A(+2'6>$D?=.EADFF=!9.B)7C/)F?25?3:H$#0H,8B&'@/5E79'0F""B"'*G=+@,)2,AF2+7#'2>%9'6,,=D#3>*8>.#B=-960;"435#H9+"*C2*C.:%AH+7:*6+0)//*;:'4>1:F%D=2*:=.+27D=""!<0,6=$=535F5?!;=43:E?869$G>!"/0!)C5(;:)"B?@+&(C7A'E#F&@F=?6CE)B*!C:D%3%(0!#/!8)@:BD;75:FA=5+#3,!7042C;7A%B7=84&%:@0629G8GFC6229G,=;<#375&?C2((,8$D($HDE7#/$+;))&2A!GC:7582E(:(6#@A7-A.7?B/>.8"*(<3,=)$?96G7+@
@r4373
NNNANCNACGNCTTCTATTGATNNATNCAGATCTNGNNCNANCNTNTAGCCCTCNANNNTNCNTTT
+
$"#!!$##!#"#!$"$#$$!$#$#"#""$"$!$"#!$$$!#!!!$!##$##"$"$$$$!##"$##$
@r4374
TCNAGNCTNCATNCAGAAAGATTTGAAGTAATATTTTAACCGCT
+
*&'$!''*&+)$(###!$'#''&*'+*)%*%'&"'!$*$+!(#(
@r4375
TTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACANTTGAGCAAGAATCGTCNTC
+
:1?4=G=1$$EG"2%6B<D!:7&;(#0,C2*?7;$4&"*D)2&='/.<#E$2C!323DB;<-53!F
@r4376
CGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAG
+
&6@/6E9(8"%F$61?.H?:"$2".4!0$99->8:5&&&C.7??=2C<7/4H<,.
@r4377
NTNCTGGTTCTGTTCTTCGTTNACATGAGGTTGCCCCGTATTCNGTGTCGCTGATTTGTATTGTCTGAAGTN
+
%&$%#($(*'+%"&!"'#%)"(''%"!')""%#$)"%$&!""#'"!%)(*%"%&#$%&&%**+&!!+')%#+
@r4378
AGGCTTCNATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGTTAATTTGTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTC
+
A72>!G#0?(E+CD(C;;%(978FB&$0)%-:="=EF,2/&&/<255G=$#;0C<8-EH@.2B+A&5&9B1?#@:)+#A%674<)=H,G"!-<6G;*24=(->0FA>D*-6:@:.+$<GDC5:/=.@=10<"@439'F*'5)6-C<1%3ED-68>#
@r4379
CNGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATG
+
'!#))(+&)*)!#!()!$(((!&#)$!!!*%)!&!!++(!*$+#"(##!(!%&$()$#$(!#+)'*%&#""
@r4380
AGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTG
+
0'*57(2<@25B8.0BG),4@''D>A"$1D0D83>&E#C1)B367D(?:"E>.?-%$5F:?9=6.9BH9>-DA
@r4381
GCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACA
+
9D-215*9B#+D4<>758@;A5)DC::>#39.,F66)311,<5@+635!6A/D"6C48+3F5D>=*A1
@r4382
NAACCAACATNNNAATTNATGAACTGAAAGNACACCAAGCCGCCTGATGGCGGTTTTTTCTTGCGTGTAATTGCAGAGACTTTNCGATGTACTTGACACTTCAGGAGNGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTTGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAG
+
((*$#)""#(!!!)%())&'+("(&&$!*)!&*$'#*!*+%)%$!&+%"&")('*(%$"'!#&%&!(*)++$'!+($+"$!((+*"&!'&#&)%*($)#*$$)&!%#)+%''$&#)####!&*&!'%*+$"#+*%('"$(*!!++%!*!&!!$(%&&)&)"*$'#$$"'"*'("'!+')!$($%%&+!'#%+(+&%(&&"&'$&(#$))%!"&'+'+($%&*$)+")&&"*##'!'+'+*%"+%"(+%'#%**'&*$$(*(''&&)&#$)($"%&)'+!&)""*%+$!&%&'$
@r4383
GGCAGGANGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGACTACACGACGATGGCCACATCGCCATACATCCCCTTATAGGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGC
+
E;+%*+31&/F28-DF.90=6?1(61+?11)F/B>;%C/C2'23.)>F$9(7D*"(C36.@G/%,/&E0(')0:DDC;!ED77-?'0G'">(;6!!D<$0=B4-=G0$6HH7B77.017=?3G
@r4384
GAGCTGATGAACCGAAGCGGCTATAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGNCAGACTTTGAGAAGGAAGATATCCTCGCATGGT
+
,"$7HC>0*93A*D2A;=4G)FEAH%@5+&$C?G="9<3/0)H>(/>>%:EE/D'+9C80?%.C8"8>4F=+B:.>>*C'>"?G02607345<
@r4385
TNTATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATC
+
&&=)&:42)@&30.)!+.><F,F?D-!'$016(C(9&7@8082
@r4386
GTAAAGCGCCACGCTCCTTAATCTNCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCNCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAG
+
H";9-9;@=@'"*C31B8!%CC7<9F?633).+)%4<4&B!??7:.?"@#3C*+51(31B282;@-:0@CCG@8*:@D+"8C(/D<8(G<C*0(!F1E2"5B%)0&;3:7FF='A?7?E*B//B#$.3%H#0'G*+337,/2BD>;81H&"$3=G3A(AF40@=12"69EC)CF7B=!?B2:6#%%*4</E?+/0)/6DD%4-%,'5H(<)9DE=0!+0F8;'&C@69%;>1;D9).G/CH7',:$+<"%?9@/:@:.-(26!:-5)=65G7?E5(68!%;1=.)C),6.BA@D$D-68D1+>8!$C,<GBG,!>,//1('7<378@#.E(9189H%:-H6$/DAF&0BH
@r4387
TAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAG
+
:==30G->$?F$*,'0)?E-D+1);H3::'G@9=37..%-"5<H()D=:=*C(+
@r4388
GCGTTTCCGTTCTTCTTCGTCATGACTTAATGTNTTTATTTAAAATACCCTCTGAAAAGA
+
;=;;>!5#F%1F:E+3+0)%=+/&3,(!#%7&<F(?9,4!C#111-17&(8.8%E25#<>
@r4389
TCGTTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGA
+
H?E+DBEE-55'4,%>6.HB*/GA!?A.A(H44+BG='/:?*??).G/5>&4$("9D)((E25)4++*D>4H6,(.D78F)0%>=@6=A00E).A',.#B=5F=B,E7&B=+>.9#1&&+G(@0,E)-3&@
@r4390
GCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAG
+
=)/;5$615=.)A1D9E0(56$0$5.6*%;(3@<'6EH934.:*"
@r4391
CCACGCNGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGANTGCAATAACGGGAGGCGCTGTGGCTGATTTCNCTTGCCCTCGGATAACCTGTTCGATGCTGCCATTGCCCG
+
D5/;B8D.@762&@:!BG&>H),>4/96,7F+.A4./E<H7<64*%G<4='&8H)G12@B@=D+":8D"-HBD'"B@50181E$FAC+<G8"$/8>?B37>"G4#5A92/AE@+35FB)!>FA+=(0"570#'2%(,5$=!G$@+*!(H?9!C%.G1)*79A$@.EG-+D
@r4392
CGCACCAGGTATCGCTGTCCAGCTCTTCGCCCGGGNATTCAGCGCCGGTG
+
$#(&+*$&"(++$$+#%)()#"($+$("(*%"%*)'$("%+"&(%*&'#*
@r4393
TNNGNTGTANTNTGNCTCNTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGG
+
#"!)#'#'#!!!#!!%&"!"'(+$"!+((*$'#!#%&&$*$&)%#&($!(&)#"+
@r4394
AGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTNCAACCGACGACGACCAGCGGCAACATCATCACGAAGAGCATCATTTTCAGCTTT
+
0C;'?A242/A=@E#?)7A'H=>=C("7;#*C-#(@2-")?"!19$:0*#(G#$BC#$@%@$F<2)%5&4:E99$'/@8F&AGD*C&9'3'%@?#</G80@E6.90#HF+-'B0#6%67G0(*$6?@29$E&,*A**&H$H&%
@r4395
AACCGGGANNCACTNAGCACCTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACNTTCAT
+
**(%#!%*""&*"*'"()%+%'$!*'"%%)!)&'$+))%*$')(%&"!+*'(&"'*((+)#$("!'$$
@r4396
NGCAATGCATGACGNCTGGGGATTTGACGCAGACCTTTTCCATGAAGTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAANGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTG
+
!@8F#-B/*-)-1<2G$4@752;;<B99C7!&94"+5?+G96GB<5,8C<@685!'*,@@H$-24B<1H+H(2,HH#(38<F?.<"4/,@)<H-$'#';FG5-1:<56)&93'<*.73>=FH%>)81E$!BD6=7,A@!C
@r4397
TTAAGGCGAGTTTTCGAATCTTAAGTGTATCTTTCTGTTTCTGCTCCTCTCGTCG
+
A3,&$C&5$$3B#GB"D;H$:#*7B$/4D=#DB64GGD/+.8.E7>$;!3+%*8F
@r4398
CTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCGATCNCCCTGCCGATGGTGGGGGCCACCTCGCTGNCGG
+
;610489?($@"!AF?&#.;@H%9E-0C)+@C1(<C@+A(,#C%+/G0;50F@28F99A;D-:>H=(%*AA)9,F2'-()5$#
@r4399
CACTGGCACTGTGNGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTNTCCTCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGG
+
5;=8>$!%$'9??/)#:%?<*<!@!:@<;B"0(@92:,CGAAG@%E,#G)/F;*:G'1H4>=/)82C=1;-H8"7494AD%0>C87%E>+D-:A"E6,9GF'9D+34*7-5?8*$*6(4G24$+F&-&";.*FF5D?$>
@r4400
AATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACNNTGTTTTNTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTNTACCAAAGGTNATGCGGAGAGATGGGTAAGCACAGCCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAANAGGCTCCAAGCCAAGCNTTCCTGACGGAATGTTAATTCTC
+
5%#C)H44@AAH"82D::H4)%'=D$05FB*,@A0#EG*<;B@C,0#4#-3#/A=H@&DG3,$$8'-?A*D+#+//26;&4A<B<+12&#7!,E8;7F0A6(>-H2BD),&9():*-<>F)?=6G#12:*0;B=GA0,>1<!HB?CG9B<=;3/=G%(9)F4='D#;?#/*2#?7#3C2G.C$=3''H;6#0AFA:D$F"0*8E'9<BB+,#5%B:CG93%&;A'.@AG,,+C6CD!@7*!@1D</);16<!H
@r4401
TTTAATATATTGATATTTATATCATTTTACGTCTCTCGTTCAGCTTTTTTATACTAA
+
>GD48G9<.<%;/;;B#?*4>.(<>,-=.@*<2/3?2/$+B8C+?<-:'*(#629.1
@r4402
TTTAGGCTTATCTNCCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTAATTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGA
+
19*:#?;B&2!>18)A2FB2>CFE<F<#<D-<)5976@6E=C4#FB#:6,:78+2(14C!9)':>C!E@2=/F-"EF<A2#%0&'@/@7,#2/1.4)F9;&C@7$=)!BBH+,.F=(&-?/+*)(08.6)%66<BB:3+F*;)8H@=1+E82!>.('D,0=,/.)EC=B?@*1B1F;,0B--<3<?E:+@BDC$;9%-'#D#>06==:6G+'?6E,<FE!/E/77>#GG!>=83@3F*G>,<G6&D3GG-1.1"@8<0E','<H<*H1D9=*(@@C"8;/HC=@7)
@r4403
AAGATGCTCGACACGCTGCAGATCACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACCA
+
D7'$C)G-.<7(4.)">(2,'=!$B=(D%$H9@G1%462'#%D@.5%H4G,F-E9:"?2B(7%#9A#92@
@r4404
GAGGAATGGGTAAAGGGAGCAGTAAGGGGCATACCCCGCGCGA
+
+/@GH?BF$?4+4B5->D<%!/&H,DB,-"@G0;(AFE?099!
@r4405
TTTTCAGAAGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAA
+
D*8;B&"A--3A(=4;G16)<)#8?1(AD*0%2.#"3*E+)&56/0=5<;!7=",(CA%AB5,"
@r4406
CCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACNTAACGTCCACGCAGGCTCTCA
+
4DH@>;*&A')F'=?6BE.0!G'D4'15H#B#FD**79$<CB)9@G.4D3G!E6(6=>29+4*=0*$FCF3.'A<;G46:54:@:$!7337F
@r4407
CGGTGGATGGCTTAAAAAGCGTGCTGCTNAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGG
+
:1-8;+&4%94>'2/)!EE-)G.<+)8;+5D/?-;=H3)&F9HH4(B8D8%"H.#.B>F6C+(2%8AGG01DE20<8E9G/E(D/
@r4408
CNCNATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATAGTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATNCCACTGAGCAGACGTGAGCGT
+
)#("C2?=?"81EE/@?25A(";H7%:6-"#'H0&5:'+<<>H/1CB443)21?C&@FF87@/<.=8:!#,1,<(?4570-!7(<E)9:,'HDC0:!)8096-,'+;!F'2B--EF(@-HE1E:)=6(*>;*=6220)>A)3.93&?HH"0)-&(2/G&5!=/+5
@r4409
NCGTTATTTTTTGTGTAATGAGAAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTA
+
';<-0;/7D%#%,#4*-!.<''#B>G.>D6<GF,&%/"=3F"---);H2$@BA14488-"+9!DDG
@r4410
GANAANNGGNNNGGNGGTNCCGNTGTNCCACGTNCANTAAAANAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGA
+
*&'!&"%!"%$&)'!")*$#)*$(($#)*#("#)$"")''*##+")+(%*+!'''))&'#%&&#&)()%$%)"'!++((&%!'''#*+!"**#)!('$)!!&!&'+)"*!"'&!&%"*%%&#%!)*)&+++!*$""(%$'+
@r4411
ACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTNGCCAGCAGAGGAATCAAGCAGNA
+
3E1):*-/.FE&H%#&;0<;'.4#-E95#>/$-5HF95:*B80'>A3G);4FD%B/6-?79=,79.+8+,<?<<(&B-7?926,?,$2/>8=*F$,?5184:+0F3GG)73#7/*3F!/",-/45==2?44H)HG=*&$$#%066:!=A#+(BA%>3>:7EC6-8?!495#/EAHH$%,>A2%;A6')A.2?36F+-+5,4<F@H8%H03G2<6.E=!DD1$:A0*7'.(=*12G%HH#5D(;=0'D75
@r4412
TGCCTGGTATCAGGGCAACTCAACCCTGNCCGATTTCAAC
+
.G18:"0?>9B7:(B085'$+F-&+HA'%4EF4)7*D7+)
@r4413
ACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTNGGNAATGAGTTGCAATTATT
+
+53=H<'?DB2:-?':CC">:B07$@:#<?)F1=!0.="A!2<>%=$#-#6-'=09$*##%CD
@r4414
GAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGNCATTCTTCAGTTCNTNTGCGTCGGCCTGCNCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTTCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCA
+
02*:"@))<(56$*C(5-".57-H1E?4"6B42149;.-H2*"'*+;-1(1/(%@*@E84(,65-0!CH=56?6@6G6-,:64DA<G99:?0966!F08)*B-6H?6F'24"HC1:>."180G>+943$+$=ADC=5D9&;=#2DB,7(),,7:%0;2@7.AG/H"1,F<H,")'$=-(5C*6=+,<;E:
@r4415
GCAGATGCCGTCNATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCA
+
DA""#<!&@/&%.;H';EHG2F6.6A'7#2+0,:<'HE!4@9H785;99CG<)@6.
@r4416
GTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCAT
+
?:9+.C;G#.,HG4;+*(1,H&+$:?DE.B&2';H24;=E$<
@r4417
CCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCA
+
1?'1*=+4;C13!E1H-57**6AD-$B))7F559*85)>*<GA4GD"1CD#/8,,'8:;1:'6+01
@r4418
CNCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTG
+
'$&F5@HA.662+F@<?.(,<BA*@+3CB<.(;);'"H8,@';)7<"#7GF6HCB296F@=4<;)10(/9"#>?=07-F&"';'40#$D6)?8B=HC/%16H,B=?C)?&D0B,6B+05*($3$B07506>!#,)A
@r4419
GCCGCCTTGCNCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTT
+
D3:,;!,.7H-87C!=C9(.2'1#G#?2<;=GH!.CA#503303:+:B9*D
@r4420
TACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGT
+
+%!((!*(+!+*&##&)$#!)$!$(#*$#$+$)%&)'"+'%#!+''#'"*!&%('")%+(+')+$'&#'#
@r4421
TGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCA
+
))H#1,HA6!C%<C<D<;FE44097,+B>F?;D8@"9@'2D$,<7&/+8'
@r4422
CATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGT
+
8AEH&<='7:3(FD8!!H</,F4G3HH.H;B@;4E4/)C4."3D467$/&G,2&@#++298F(A/;6
@r4423
ACAGAGGAGGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTNAATGAGCCGCTGATGCTT
+
<$>@9%+'@//!#3/02.F@',G1?0GB3D)!$6>&6,-C'@758!'%=DG)B"8-%2:90+G+6;%G$C4>'&B>4B?#7=
@r4424
TCTCCGGCCTCATCTTTTGCCCGCAGACTAATGTCTGAAAATTGAGGTG
+
/)%96@0=27/CE&32*)90?%$C=9*96:-.0A11/09H.CF>04/!5
@r4425
CTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTC
+
-CD&&DB8:C85*2F+>(>%<$1.A/004+>A<=;0H9>&BF62%'AG/#B@9'(-9%?A%FBG%,&3/:&,
@r4426
AAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCG
+
&G"*71>4@7B04%&3-9C)A%B<9D1H',(C28:)C.@?96D@
@r4427
ACAGNNNCGGCCGGCTGAAGANCAGCTNCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAA
+
%#((#%#%"+!($&#$#"(&*(!"((*+'+&()%$$&$'"&##+)'*!#*&+('+!+&&%*&(&&+&()!#$(%&)#($+'
@r4428
TGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTANAAAGGGGCAGCGTTCATTCCTGAAAGGTGGCGGCAGCGTGCTTGTG
+
C=AH6/E.?F7A@/216G0!046CC7=A5;0@2)6D()&.0%3G?G#%E?&:.7=.-F)'!4#$3!/&*4?/A(0'5=?<-BB@C<B%'6@D7;/H33G*!828
@r4429
CCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGG
+
4=?C5+<8$-&9>(+!H61+CDGH526!=G.1:,=&<H/'/?*'<$BG(F3)D,-?4/HHCH(!>=/D8-3/G.&#2;,$93@0*2F%0.)@.&-5%':G6+,+>)D'1F/29'D?D>/'2GB0G%!39(83?,"*>'17.)"*0)H02B=)B8#BE1#?/G!9*;;B)9C=C-A(HF
@r4430
AGCTGGTGTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTT
+
A&9CB:687+E",;F3'D1334D?&H&9"!&&G.%8G'@!6F.DCF3
@r4431
TACACGGNGATGGTCCCGGCGTGCGANGGTGGAAAANCGTCAACCTGCAGGATGACACTGTACTGACCANACTCCACATCAATGCTGT
+
:E1&6B)#4C/@,=18A.$>0B-;?.?&"@2A'H)+?'42A3'D279<C@F>;.:<A#F7:6'>((3!E.'5,(*&H%B8('&<77F1
@r4432
TATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAG
+
G!DA#?GCF0(DFF&9GB1%6;?#F-.6H#:89@A05D$C*;24+(2H(3)$
@r4433
CACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTAC
+
41/E9#,!914A?7/'F;BGG/*:25%3$85'!1<A$(:-%5.!>C%E.%;/5"5.-
@r4434
CACCAAGAAGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCA
+
,*-F=+"-!?4$8.$5#+:0:6D99E!)6&><+%22&;45$)H$6&,*>4"H#3>=HF3";%6
@r4435
GTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCG
+
=$#9:&C#1F:B>#3!7887)!(*071>A%/%>H189'2H3!;A+-0(08A+)@!G*9$'C%.76'@%*3D.')?8-@8*G(084B1&5.B!0$,"*@(14E7>(06</2G35//
@r4436
GGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTNTTNTCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTA
+
<EDC>2*;/!22+:E.@,=H-@5'5H)?>.&=(1/>&E2)"%;41(9#/*).*F"9-H-,%2/H887&$:/F/.2=)>$C2"A(,=:-5&04A.81:BBF7)2/80&"0C#9/"4=3-28*GF*#C6168A:#,,$$GC:D4#-E&*<.&346(2G,)%;+1;2>4/31DD3%#F.09G6>7H,')?/D9D(.11)F/>(4G>7;9%0:%,D#)3-;BE)*(A87(0F&A<*$D#);;,0G2'2.A3.(E4&*E06B0)#9A8%:73<=+F+
@r4437
AAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGAGCA
+
5#C"7.C81@CA*%9!%"3/'='61AG!F*-"8*-E?A!67.:.5)&$18D/9-!"!*%>#E0<C4F4.CE9%>5+?C;:':C/H&&H1->A=AAD"*;:3=0?
@r4438
GTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCTGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGGTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATANCCAGNGCGGAGATAATCGCGGTGACTCNGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGACAGTGAAGCCCAGATNTTGCTGCAACGGTNGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACA
+
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
@r4439
NCNNTNNCGGAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAANTTTGCTCTGTAANTTATGAGTGTCTTCTGCTTGATTCCTTTGCTGGCCAGGATTTTTTTGTAGCGATCAAGCCA
+
%'"!$)!%*!+%#*#(%&(*'!)(&$$("$''!(!+')$*+&)%)!)%&##)%*#+$)$('#*%("#$"*&#''##**"*)''$*&")%+#$$##$(")++)$!+")+)+))"$")"(&'+++(&'#%)$'+$*(%+&$(%%'*"(%
@r4440
GGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGNACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGNTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTANGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCATCAGCG
+
/H#5HB;4-9'-@0#8DF)8;95/.-!,$1A&80"C1,=FF.#(.?.+6-623':&.(6%?'.C?$-$/::/8=F71B9*=27-.87!+<B)A2$FB"G97A33=6:AE(>3)29$:F>1$E-CB2'H*$#<>-<4-7;H%.!>9"1.F$=*7C8:6-"(5?0;%4#,@#4%G:;;1&4,3H#"1@8B/*++'?0DC56*2<@B+2:-HF"--@/,.%:?)-/,@@0:/):,0'.2!GE<BE/C$'#
@r4441
GCTGTCCATNATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATTGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTACAGCCATTCT
+
D?!/$($=/7"D'"G-#-C9HA++53<DECH"=G8"5<2>D.27/>+7C8-G&<%A,FB?8-2.)8&*A1$*,%C7$-G&.7D>.);#.#H6@$GF>.7#%(2<*/'14(@*<%!.$*28*A7
@r4442
TTGTAGTTTTCCATATTTAGCNTTCTGNTTCCTTTTGNATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCNAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACNGACATTCACTACAGTTATGGCGGAAATGTATGCATGCTGGGTGTGGGGAAATCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACT
+
6"*0G54B:'.16=C<#,DC2!BH-$'26/>.F'.=6'FB-H6<<<8%G#)()=%H.84A5(4.'AB4-$0@,8"=3G@C#,-HG:'#>B$,5>&.E/?)$3)324-FBD74)B6?>'30.?H)/704=1,>!+3C"=08$H%@+)64B(?H$=27+<,9G:B:6H+3A%!.&;D"&@CB)07(4+,$>D(8?;@77;CH(#=$B3=6A($A+-74389D#E!-B#:!HD$.436/F0"FB'&B*-1#&*H<*$A,!/$(&*(#$9=CF=,61?*1C77@11(B51@"C*7/63&B7@A7;@,8)D!,8@6G%A9A5/4#C@4'H/9<E9#%@6=0;%*'#
@r4443
GGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCA
+
7GH:0E;"$,8A09GH9A5'6BF8)F,.E/::;+-.4#27*>#9')':,B7A*1*)<4E6A%"EB-A3(:$60,*.8<H<,-*8965?<
@r4444
CCAATCAACAACTGTTNCAGCCACTGCTTCGCAGGCTGACGTTACTGNCGTGGTGCCCTGTCAGG
+
%=B@.71(07*05*%..!*C+*@&0>/!F#+%H/+$48?H9<0.:,6--D9+@:64/,5%5/2A2
@r4445
TCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGC
+
$+!8ED=(%$,>(D5E5G44E=)/$DA1FE'!C=::2%A0<>/
@r4446
CATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGA
+
4'9AGE33@>34HF31'=11A/;8::@B<!2209$B$70%-!H41(3=E+/1."D1#6:*!*"E?$5!.F+G15+F0)>A
@r4447
TGCTANTTCTGNCNGATTTCCGTATGCTTCAACGAGCATGTCTGG
+
6@-+><;H,25@B91@#;09/B$.4B0'F&;:C'909:!%'F"@#
@r4448
NANNTGCANNCAGNTCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGNAAGNCCACGGTCAGCGTGGTG
+
'&(""&$$$#'&$'"%+('((++"'+(*!#(+'$!*(")!#)'*$")&%*"'!("+!)&$+'&$*$($*#"
@r4449
NTTCACCATGATGCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCC
+
"A9E+2,--?A;B4!E8D+.+8AC!*=?53$(%B%?'<:GB!(/3$/A7@0)8(8B;HBE1/B3$15#G;6&2C'C,:2<@08>>/$D?-'.;%
@r4450
NCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACG
+
!>=(453C&4@!+3+DEH6$D===>90.68FGE"'A4!!"
@r4451
NCCCNTGTGCGTGACGGACATCGGGAAACGCCNAAGGAGATTAAGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGNAAATGTATTCAGAAAATCATTATCA
+
'?/*D'?G&;)82(0":HB$6?A5)@:>EE5#<A#@07/(6@(,;A@)(<HA7H-C1B)%,!*<D0F,9$$"*B/C,9*,D)48@&1/(98)4%<);)A603C(
@r4452
AAATTCATGGACAGTTCGCANGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCAACTTTTCATTTAA
+
<F+8"!!CC@/#2-3>&GD>&E:1%2&1',@2@&C?H=.'5/=F4#H1$F/2/3D%">#8/'(?H+5!B$
@r4453
AATTGCAACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATA
+
9F,*8$8!$1E$6>:C)B.6E($6+4$1.B;&47'FH2)B.9+84+3E-FH"4$2(0%>?GD:/+8;H?)F*<>-+89*B2&,G0!")<BE*26B&,)G<CAD-/:)/-0*)"B81DH!*9/81-1H),3)B1G-?+15@-*F%8%6<0+8E@083$?4)&94HA%=%CE"("4
@r4454
CTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCNCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGA
+
4$C:2'7-("7H9="/4C/B>+(77'A7!H2H*4,"GF(-D3"E-09..'-(GD;17C;&&::A9@=9#=84?>0E9DC@A$?A1!H=5-?8<#=)(H&D6E+G//+1<-&B3.9/B,<G.AGF=608?72+
@r4455
TGGTGANGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATCCCAACCTGAAA
+
H#H6;-:/"D%F+//8"0D8B&<*""*0B:5BG@G/=$@H5CA=F9+::!?#
@r4456
CTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACC
+
H7,.-1.0;@A%3C1%;2=3(;9/F0=1%DB-,+,%,=#&
@r4457
TNAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAANGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTGCAGGTGTTCTCCCGTATTGTTGACATGCCAG
+
,"$G>&.6.".925G>F692:+)*<4=HB&@+H"7C&&+6>6A+;*B$3CH.","310BE@B027=AA!'79&#8F7%0%.1%("'9""2*>/HF-"#=1>1&;8:D4?;G4(=-=/"@B-9>7$62+.8/.%"(9'<;+4.G.,6)-<*-?D1H/,)&4-0AA95+#;<'E)&&;22:;>?1(53E;0+<FFG7=:A5?5+&54/B;5:"$$;+/
@r4458
NTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTC
+
!9!.??5+=$G+/=:>G!/@=//!6%847#:'#'C>#4=+,!($&:-A*/H)>(40,DF773
@r4459
CTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACNCTTTCTGTCCCCCGTGAGGAGGCTGCGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGANATCCTTTCTGTGGACGCNGCCTTATGAGTGGCGGCAGAT
+
+)++%!+')(+&%'$'!&"")!)$'$!%#'"($&%%%$$*#'!"!+"$#%*'#$$$$!(#%(()(*!%)%!&#*+&$%%*'%%#%((*#'+&(*!"))&*"(##&+))!")$$+)**&(#""++&!'"+#+&#!!"!'(#%++"&
@r4460
TGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAANTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACGACGATGACCACATCNCCAGA
+
@%3*H>"C%<!CC/>0>;(>-'2<>C7@FB%6D+7<&07.+<B(8DFG6DEF#H-6&G':F$<!<"/A'"<0;282!5(3%4E&)!%>,.$HG>*;3&=4F@,@#
@r4461
GTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAAT
+
-A60@AG,.B=61?A&3C*E0&A@:CFC":1;;9;(-%,885+)
@r4462
CNNGNTNNNNANGNNNCGCNCNNCGNCGANGCTNNGNGATTNGTNNTANNGTCCANGTNNNCCCTNNNNGNNGNGGCGNGTNNNANCANNNGATNGANGGNNNTNNGNNACNANCNCNNNGACNGGNTGNTCNNANGGGGNGNNNTTCNNTNNTNCNNATNNA
+
##!"#""!!""$$!#"$"$#$"!$#!!"#"##$$""$!$"#$##!#$$#!##"$#!"#"$##$!!"!"!$###$"$"""""!$$"!$"!!#!#$#$""$#!"!$#!!#"!#!""####!#"$#!"!#!"!#!"""!!""#$"""$"#!"#""""$#$!$$"#$
@r4463
AGTTCCCTCCGACCACGGCAGCATATCGAGGAACGCCTTACGTTGATTATTG
+
?0A+<%+0B8DG%B-G$6=*E?=>BFA39&A6?H61,8C"94H,'8>=6).D
@r4464
TGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGNTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAGATAGAT
+
9-,A!,GG>'@8@*,9/"B@4//*5+&28-<@:0!AH2@:6<;>,3<E-3=?6(/H$G6/%'>/&!7?';,F'!(08"3165=.=,"(69"0><?$,,<)$*G3*0F<6B::H*;F4D-5=!#*2?2C3F)D
@r4465
CGTGAAAAGTCGGTGGATGTNGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAAT
+
<"7C31#6A'F#!;B$9D2.&8&7#B(E+9.>9F0$5->HH.3HHF$4&7&6!7/+<67EC+6+0H%&EAC"G<"=*>(:-D!:7@;0!D;8=:F11BD&0"0-%&@=B3:>6?AD@D-/E/,'F<3)>/<(52--$%7+C:HF;,>;)3;@2'--;?%AH$$.'A08=&34C7(@'=FF,%.!<@(
@r4466
ATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTGGCTTGAAGCTATCAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAANTATGA
+
G=8&9#C((#<7;50'7+@E#"&=7/F;6,4"8D!9D10%>D&FD(@H*=/<<?D/';C,1!;>E$$$AB6G:''03,*1,:*<-42<:1FC:)+B8B8C)0;<+%(=4.9H4G,9.BB6
@r4467
TTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGC
+
H,:"#/9.!(+C"'/*)+E&:+!*0H0),D=8;1<D2?!':;
@r4468
NGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACG
+
#CB.20@(8;/0>5:1?)0H4FDD<.4(BH0>+:&#9D4A-!9@.1!D>/G&3H%;=8*704
@r4469
GTTTNTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTNTNCCATTTTTCAATAACATTATTGTTATACCAAATGTAATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACNGTTCTTGCGGTT
+
2E+3(-?>)9:6'7+8-4C#%0!)D!(('0>?FD,)<@2:4-='=6@<?92@G.-6>3(#9A4"78@(?9EH2*B35B&)"G=C>,30-&=+<'4G!*A<G)-+."D.CFC'->:>7$AH1-+$6#<D8C.F,)C?)26;H4703+B?%
@r4470
CTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCA
+
=B892D?-'.@10!-9A&@;;*.!!@AB,'>3H@B*&)/3274)/!(D)C#3:!35G4/&0=)1G+HH5>6F+C'@H1#>02;0%+FG#E
@r4471
NCGNCCTGGTCCGNCTGGNCACCGCCAGCACACGANNACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGT
+
%*#")%!%(()#)!!*$#"+%)*"""#('(!&"'$(#%")')%"*!++'("+(#$!&*$#&%#&((#(!#!($)&#+*"*($((%%+!($&)#"+)"('(*!&#$%()(#("#%###$%+$%%*)$"#*+*'&'!&'$(
@r4472
ATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCA
+
-31.*@#F;5F<$E,./+??++2/'*<6;(#,CB>0:D5B/85H,05E:CH;5B+2
@r4473
AACGCAGACCNTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCC
+
;)(/!46-3/"F<%@:E91#6%74E!1&H#/!4;4+$9,B>"=0
@r4474
TCCGGGCACTGGCCACACAGCTCCCGGCGTTTCTTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATG
+
&#46E:!G+=GA*,*86BG#'F!A<H)'68?E,.2'7(5,@17?!E6/6"!D%;&9?@$8".3F3,7H:&!*BF&"$D-4E?!"'A?>C7@<",B;6=2,E2$,*+F%42&C17@/0
@r4475
CGATCCGATAGATGCACGAAGACGCCTGNTCGTTCAGGGTTGTCGGACTTGTGCCAGTTGCCAGGAGGAT
+
0F,D<=9!410DD=*;:?A?-:?B4B('H:1)3)9=H#HAFB,!8<,6DF!"F@+EA/48C)>'=H@&?0
@r4476
TTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATCCATCTGCGATATCAGACCACTTCATTTCGCATAAATCACCAACT
+
>(:*#'!>0$2F>%>%+='#HD<0)77D0&?<$8=@79/H,$!&D.1B"9?F#8&0$5(C-*68;,G@*BH?-<BG/3>C1('.)?#,#?C&@?:$B<""(:E7/.6;70?"31280F07<5#C;%+>?"9F,E%1&>/%@CE**97H6;C$:96/&DD9"$!)=6%;#B9
@r4477
TGCTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTGCTGANGTGTCACTGAACAAGTCCCATGTCGGCAAGCATANGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTTTTCGTCTGTTTCTACTGGTAT
+
1?,!'8F$DA+=/E5-E/17,0.6H!9/G5&-)AD1AF+71,0"<?$"*B4H?)H631367"%%C!0,2=**FH9=?,/3$/G;*?$!.='AB!;G-)E;?-8E,CH!3.7@>-5EF@D;>F#-/>/$,DG;&6C@H4):0*CCC:&8&FB.;*E2%.:*.2';E8;H2)157<5.?&=2-0#.85.<78D6F+C&C#3"(D=.)/3A*(A&@3-=-#=.(;51C4"C>$DF4B(<")=%6H:):'F@5,+C9F"B*3=EE,
@r4478
TACTNTTAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATNCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCAACAACAAAAAAGACCTGCTTATCCCGGTGGGCGATTTGGTTGANCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGNAACCATGAGCAAATGAT
+
(*%"#&!()+#()$'$%!%$*#%&+(+!+""!+*#!("+!)%#"(+%(#!)%'))+&%$#&"))'+*&#''("#*!(+#!(+&'&)!%")%+(&**$%##$)!')&&*$'")+"*!)%!(#%&++%+""*'$$!)"!%%$$+#$#&&)##(%*!*$&'%*%$'#(&!*(!%&#""'%*!$*))!*"(&(%(!"!'('(##$*#()*$!*#"*$(%$%$#"'+''*""*%&
@r4479
NCCAAAATCCTGCATGTGGAAAGTNCTACGCTCAAGAGAAGCAAT
+
!5'':G;!+H/*4;15C9DC$*F;/0"$3/;.4D="B)>-GCH<B
@r4480
TTNNATTNNNANTNGTAACNCNGNGNTANNANNNAANAACNCGATGTNNANANTNNNAGNNNNNAGNNNGTNNNTNNNNCNNNANNNNATTTNT
+
#"$"#"#""#"!""#""##!"##$"$"""#"!!"!###$#"$$"###""$$#!"!!!#$!"!"$"$$$!$$"!"$!"###"#$"!!"#!$!!"#
@r4481
TTTGNGGGNNGNCAGNNNGNGNCTGCNNCACCNGGAGGACGGNTNNNTTGCGNNANNCGATCATGNNNGATNNNTNNTNNNNACNGGTGGTCGTNTNCNGGGNATGANNACNGCNTATCAGNNGNAGNNCGNTGACNNNTCANCCNTGCNNTTAANNGCCGTNNNNTCNAANAGNNNCNNGNNTNGNGNANTTNANNNANCGTTNAGNNNGCTNGTTCANAACNAGGCNNGCN
+
#"#$##"#$$##$"$!!!""$#"##$""#""!$!##!"!$$#"""!"$$"!$!!!"#$""!"#$##$""$##"#!!"#"$!"$$#$"#$$#$$$!#"$""$$!!"""""$"$##""!#$$#$#$"!#!!#!"#$#""$!$#!!$#"##""!"!$!#!"$$"!#$$!$$"$##$#!"!$""$$$!$!!"$$!"!$!"!"#$"$"##$"#"""#"$##$$"#!#$"""!#"!"#"
@r4482
AGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCC
+
E6780:#8.:<4/7-H>F#E'=:'20=1FEG6=0-F"90"/82(8>1G"?-;A*53,E=%-!)7&?@9@+$D6487E#*<F#@0"..H8'!(+5?/1,"9?E$<%!+
@r4483
CGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAANAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGC
+
<.%)(9,'!1#50A4*;2"4%4FD(</-'<(G6>&D!+?A,0/=E+A#"6)6H-"#H!""3?E(7>#!;.:9:@3&C:@4.5@A<A=B,
@r4484
ACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTC
+
9)%<.@3/+F::+&F3+%<>0-DA2BBE96=.F=%D"H8,>15H:7!5"-E>=D#F$-#,9A?,"94B0-.
@r4485
NATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTCGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGT
+
!50DD=#6>18"A+30)/?*2,:>41$4H9?+%GA82C&.H*-BB#A5C9)0F?%)B=:A0=/7%'@,2,H90544E(&.63B%
@r4486
ACTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCA
+
!>D@BAF/B%;F4*H!8;&?D&47@BC.;5*/41;C3>&!80:'C3H*9/;@H=,.&/1149*;)D20&:=GDC"F;C'9#H8)>$G.)/B$"G09.)+;+@68B=
@r4487
ATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAAGTAACTGCTTAACTGTCAATGTAATACAAGTTTTTTGATCTTTGCAATGATTCTTATCAGAANCCATAT
+
0?>?CH19C<=(6(@#):0:09"&"F,*-524A#5.)<()HA"&H//*%7"<2AG.A$<%>#0H)0/#/1D0A%.#47G(:F3,9$&>A=9!/-!;:2#E!<B/&BAD/&.=D
@r4488
AAACCCTGTGTGCNTCGTTTNAATTATTCCCGGACACTCCCGCAGAGAAGTTCCCCG
+
E,?E9E>>C>&.;B$G:48.B"=?@+B#($&8';8'*6"-(02F4'?E);F#3HH@E
@r4489
TCTNTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGNACTTAACGGGGCATCGTATNGTAGTNTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGT
+
6CB7G>G:;D/%+!!?:H%6((::HH19"E+4-B=G'@7;&?;G7A&*1;/?G*5F&C,(%;;B4%?""GF9@>2!<5'A1!1;)/#@&E)@-H+A01HB9@27="%!F!B@H?7B93H*>/0-0?B8C$2$.HD0%:'6:('?,98"!(
@r4490
TCTNCGCTGCGGCTTTCTGTTTCAGGAATCCAANAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACG
+
$#%$*!+#)(('*(*+(&*'#)(&#!!$)#"+"("%#&')))$!)!$#+(#!!"$(#!#!$!**))%!)'!(*##!
@r4491
TGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCT
+
G4.8@*<$$960;FC:098F&(F,0EG"0;D&=H$H63-F+'%H*F-#+40&'/
@r4492
GCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTNCAGAAGGGACCGAAGCCAATCCATACCGGGTATCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCAGGTCATACACCGCCT
+
(?G::)4:+12#"7#0H+&F@E'@3=4&&5'6#%;5,'/@FC>#+E>"5!B./"E:&:$'D9-0;B+8F<8C9&>$?)+H2B"B)185+-+@45G2D-&."?F"+0C0&$9"8##7EB$,F3F4H?;7@"(0D<H*%!6=>;$"<,18B"@):+1(<7.3>503@,5$($F&H%@,'0>E,$H84@G86B7+*
@r4493
CCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTAACACATGACCNTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATNTGATTACTAAACACAGTAGCCTGGATTTGTT
+
D&=F?-((%;B@51?&7<37613E*20-.B.+F%&:..@1;D#,68F:0'*C,%#&66-56C=-'1#5-4E.*CDE$'*'$'A4%12),CFC:#>4@5+AD33:%>5*AG-!!22>..B0(*",=<E3%C:B/'EH5H0D>:@7(>D/F8F7"'2<
@r4494
GGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGA
+
H07FDC7%*>2)7-#02,0*+3HH,EA,1GB#'!68?>=FD7CF>%/7%#?
@r4495
CGGCCCTGCGTTTTGCCCGTTGCTGCTTTGCGAATTTATCCGCCTGCTGCGCCAGCGCGTTCAGG
+
/21.CFFE:'37#5?+2=7+@DDB?;-2/;'C#,,$C9$F)&<.A#)=D.(?8D88/B59#38&&
@r4496
GTNNTCGTTCTCGGTAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACG
+
%*"!($+""%#!')%'!')#"'$&%!"!#)#)'%#&"#')%++(%(")"%"*!&'
@r4497
GTANTAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATCA
+
)(&"(+(')()%%(*#)"')*&''*&"(*&!(&$#+**"%'+%%))%'*+#&%"'#
@r4498
CGCTGCNATATNTTTNTTCTGGTCAGCCNCNGAAGTGNCCNTAANCTCGACCAGTCGTCCGNCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGC
+
*#!#!%'#')%!*($!""(%*$'*&&(*&)%#''#%'!#&#')'!(*)"$''&!&*+%(!*&&")++&**+$'+'+$#!!&#$"(!!**$&$%('#+($(*"&((!
@r4499
ATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAAACAAATGTATATNGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGCCAA
+
<*9%0217?%4E&"57,?>*2>#+)/9C7495-1!6"85,D*G'.(*%G50G"F&;14'(;&8&0"$.=!>1-,D)ACA>%HB/)')='!+E<:>.1B&+(+G0EF9!/*C&3(G+<5-F4G/5F$<%=.F@$4%C=0!/>%.51@6&''F<!
@r4500
CATCAGCGTTTATAGTTGAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATNTTTAGCTGTCTTGGTTTGCCCAAAGTGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATAAAACCTCCTTAGTANATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGAT
+
+8H@./4%$$64!-'E&B4@6+0A-?0D*>(CH;2:F/"2>84'/+</B);,&&A!";)3"/:"B:+%+!=HA&4A9.<17(=0$@5=C6B"@G!G+.%D97)5C,&+'FC;%9@?6A@9<7E='15;2;<GCC;<-B"9+'H9;BB6%C9<-C'.>E4$60&'F)(.8@21/'0@9@9)(F515B&B3$03,#$-<&*8=;+A?C'EC#/62H+6()2"6A44(!:,6FE
@r4501
ACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATNTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGTTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGAC
+
8+/$B("ED"3,-4,48/6DFF%C<ED&2C#8;@&13";$26-22F%@D$)>!04>B)3))B$'==,$D%09F2.B?./GDH*+G&E48$$5BA:@E5.3/06+H8-A8;/!E4D))>;9?;26F==;0=<6=:/&E?)-?,$161AD5A%D-%.FC/16?G-HD=:&F$86")99H42C7391'00)'!$-97=!B;H*(C,?'%""#;;;9D"1D8!42)"?A'
@r4502
ACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCG
+
8H*!.;:)/"G2:&60DE5(%;=8B,!D2=!2AC'?,.57'C4G&%=BC#>!08('%A5:8"(+>%(@@%(F-(;-H1*%7.F;)7:<=&B!H)'4@:H%@E2AF+2>(!"@-A70F+451?5(7H-)%H1A>E564C*"3(/#+">/37)#=$6E#1;9&(2@7'<D,GBE6?C41GG@%8+G$>2B.8*3!GF>7G2$<-;6-C<7GH;/
@r4503
NAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCA
+
"4H51EHHA@8A+!3?"D"H/(-.7&(A.E-C73--$($71"9/@8D.?7)+>GD9>
@r4504
NAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTG
+
)9"@FB'.$?;C@):)C"6<093$#CE,',A$2E?!G?/">AH=5#B8/<;6'!?D5BE"9!021'#>9>H<$.,B",?5=5B+A+*02/4+/1F=/)EB>E-"B.(A,*'&,6D=8*8F%.7>,4;:2%G+,9@)##G0+?#-C
@r4505
TANCNNATANTGCAGCCATACCGAATCCGGCTTGTGATTGCGCCA
+
'($&"(%%"$%+*&*#**'$%"%($$#""&$&"&'*"(&'&')"&
@r4506
TGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCT
+
B+49:#,?C%#=F2#H9D<;$0>&"'$2'!=5C-CD2G4.+9D&5''-7<74G=14C"28%<@;=;"(;B(>D"G:15
@r4507
TCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCA
+
E9!$H5%A61B='*(-@B9'=8-?H!HB04G->;3*/13EG/,(#%>*.H"!A3,!89-H
@r4508
ACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCAT
+
481$)%(*2&'(HH87B:%?H3.."F",/9-,9%#B@0=%*(:*@D4D<*70&)?=41G>"#(A,9?1A+>*5%C=FD;4<0&H9'"&:%1&,9
@r4509
TNAGCCTCACCGCTTACCCCCGCCTTAACNAGTGCGCTGAGTGACTCGCT
+
(-:&!::C)#@57;A+9!,*<66@;>D>D*D4)C-G=+4EA<"A386/)$
@r4510
NCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCC
+
#>(6@7@3D5:*B1C*7==#/%C/=H@+$<0>?$)@(0)F7-F<<%-;B-';7'0<><G4@2>"G+<3B.B()1<B0AG#1&:3-/=%/FD/B59-'2=
@r4511
AAGCAATGCGTGGTGTGCAACCAGCACAANAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGAT
+
?2;$(%BD5:58#7;+G"?5'105??:C3440*(!-.,$"E>@:(C.!(5?+.+<;F+/>?&G,9
@r4512
NATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCAT
+
!;2=%*E,5*."60(6'!".17/33>?0')'G;<,/C4?G$D&(6@G9H8
@r4513
TCNGTGCATGCCACTGTTGCCAATGACCTGCCTAGTAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACANCCCTCCTCATATA
+
;'#C,H>5/!><%"+8#:,CC(@5)B<898'5#,!%6B5G1/#G3C0#H-H-;6(!4A'DE:6($*C7*E1FE*DA&@)B&1$@2:&!
@r4514
TNCGCACGGCATTCGNCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGG
+
("$$%!(+*"+$'*+")!!%'#$"$*'%$&+($)+)")+'"'+%!$*)%"%'#%!)#)!)!(#!
@r4515
CATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGA
+
F+/&6?#GEG".@/?#C4+!+%)$,G?6$(,/F3$/F0@5,@3@C
@r4516
CTTTCCAAACTCGCATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTT
+
56,3-A#&G7DG'0*.6B%.3(*)"#5!2C"&74<;,-!!0=574G#38:953H3
@r4517
CGCCCGAGGTAAAATAGTCAACACGCACGGTGTTAGATAT
+
E%:7E9/.B63%/8C2><&&2;0E&5%#-@B@*5;5#$.3
@r4518
CGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCG
+
9);&>.@F(9&GG3?*(;FG;AF%''8.='F"8CFA<8A5
@r4519
CACTCAAGTTTTCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGG
+
5?05/@21&;7#7D/@?FB<5?9@+C$@@&'>)0+DE%<&0&+/3>-+0CA2")<E?:E@DE>*CA!E1F0@,<%*%<
@r4520
NNTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTAT
+
"#%'+)(#(&&*"+$%'$#"'**$##!(**'&'&#"+!'))!"(()!")')
@r4521
NTANANTNGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCTNCGATCTTCGCCAGAGCCTGTGCACGAT
+
"$%)%$%#"*#'(+*!''(&&($!!+*$!!"$*!'!()"%&!!*#+("$"&%*&#(')**+%!#)'*%$$+*$"**'+!$)$***'($*(!'
@r4522
GCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCNGATGC
+
7<HA(*5>5(69,C;>A<G=;(.'3/(5)C8D.1D*2)H,3-E;:-7/DA(!/..20,@)(C:=A84-/+)9D
@r4523
CTNTTGANATTTCTAANGTCGGTTTTTTTTNTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAA
+
*&!%)&#+")'"$*#%")&&+#$&)+%"%'"%"+"*+"$'%#"&%#*'$&$#)*$)+*"*&*$$!"$$&+("%'%"!&('#$$(+"#
@r4524
GGANTTTCCNTCGTTTTGAGGGATNCACCATTCNGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACNAGTTCTAACTTGGCTTCATTGCNCCGTTTGACAGGTAACTTTGCAATCTCGNTGAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTGCACCCATAGGTTTTACGCAGAATGGCANGCAGCACTTTANACTGTCGCTTGGTCAGATCT
+
5&1,,.<98<G)C#D"&!>)>1>((=C9BC)D<3*->&<AF,H4G62<;"$24A,C'D?76"2*;+;:>;/E2B98F28DBEHF273:":!$G>2";#F$1C7;3)A%G%E$"5A@?D9EE2"754D&%+29G:#31#AE%H>24&7F>D:B+F=!.=F1+*!/-C4G;?*>,D*@897?#$"?D"<(&78$659B=B0=**$D4BF4':@3*@G;>@<86D?#5*=954;7.7#B'H>399A<
@r4525
NAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCNTTCTGT
+
%9-,B*<,*!DH2%A*2.)#-(!<0FF/:')>A++'($*-C<A,7+9)'C/9$@).31>&""A355AE!E.%71ED.1C(7=;E--1-&B!$,!-A-$$*C+0B.E5
@r4526
CCGGCNAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCNGCGAAAATTNGTCGCATCCCGNCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGCTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCAT
+
*"'%*#)**+(+%+)!)(!!"*&'%!#&#!$$%*&+(+"%"'%*)&(#$#$%)&!&+%&"#&#!"(%#$$)"$""*%%+"!'+!')+##"#(!'!%!+*"%$'()*)!"+!+($#"'+%+$&)!!!'#(*$&$(#*$+%%!+!)()##')&(&#""'!"%$*"""&&&)%!($'"("&+$)!$%*!&(!!!%+*)%&"!&+%)'*#!))
@r4527
ANGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAA
+
!%@C3G!DF/*#>&-GA;50.;!71-A"@F1%9-$(9GE2E'%6(6)&6:5G9+GA9>G+BB64+F2#CD&%B4>-D?<)!-7D1$=>"5:!:@5(:;4;6&4&'&&!('/:2E6
@r4528
TNTNCNNNTGGGATTCTCGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCANTNTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCNCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACGGNCACCTNAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCTAACCATTTAACACACGTGNGAACT
+
)'(!#((!'#+*))"*%!')$""&&)$%'$!'+#)&&*&$&'&%'&$*$'#'"%)+(*(&#%)')*&)&$)#(+&&&%#%')+!((*"%##'!(%$'#$#+)%('$#**#)!#'%"$#(*')%**&)(&"#!!!)!#(#+#%($('+""&'(*)&('())&"!$($&$#&)%!+&+$*#!*+(*"!)')()&$%+''"+)*"!$&)***+*#"&!$$""&"$(&!''($*'!")"'(##")+%$#$&$"%&'(%&*'*!%+()"&'&+&!")%+*")
@r4529
GAGGGAATTACACCACGTGGATTGGCATCAGAGNTGATGAACCGAAGCGGCTAAA
+
/F@F*$;"(D,3$G"GCA%5#-7?D<C2?'<C%%CD**CG'2/D#8A0G-.;0B?
@r4530
TGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAA
+
'1;H0'EA.+,*4E:!%9E=7F)"&*(>*ADE'!@*37H,"1<6?+=?,*B6*=?01E63=A>H%,,CH
@r4531
CGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTG
+
#H#B4.CG*4".=C@-#@'7!88";8')89EC7<B,=#CCA12;0E/D>,%@8)>#3::
@r4532
GAAAATGCACGCCATCGTCAACGACGNTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGC
+
2*;"=F"@8*3"81!B.C1"'G-)5:-+F/0@$)0(-B<)55",G@EH?459,*"<-2%.%!C
@r4533
CTGCAGCTNGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCNNCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTNTTCCGTCACCCAGCTACCGTTACGTTGTATC
+
'6#7A(B2+-'6-,+"&83C1'%?$!H+,++:E6:!$(-&'/3&+H!C/'&+,1/E%,#=1?:88;3?11C6?62,F(*"4:4!/0,@!4F??>8:+64D355<,/)9CG&A"::CC8/$75)3(41H=+*EA9=%&!H#:2+'<D-&$'<#"<3:D:E>%!G
@r4534
AGTTTCNCTACTGTTAGCGCAATATCCTCGTTCTCCTGGT
+
G4B$:9(=77'3C9EB'=55"&@42E1F=B2:-27?>"4?
@r4535
CTTTGCGTNTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTNCGNTTCTGATGAN
+
#+"*%"&!%&"%!"(!&%!"(("*!$#!*!(!%&"&#(+&!!$%+)%)#(*"$!&(%!*%$'+#*((*#)"#$%%)*$$+&%(*!()&)(#'%$!)$+$+)&$**%*%(#+&'%('*'$%"&$'&%)&"#"'*"+%")+#"%(+*#)%'$#+'&+(*
@r4536
AAAAATGGATATTAATACTGAAACTGAGATCAAGCANAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCG
+
H("86ACH"!7,>13.3=#+G1&/>6$6+1/9/CD+G@:+;>-0#EB)(6G!)594:%%@?+A7*#:&G5.29>":?=%F503$F+'8AE$7$)?:G;;-'>4<#059-3E4#"!&0B+-;B+=<(54'1>("?=.34210+,'2B3/(>)$G=HE32/C56$CE.298G$0$+
@r4537
NACNNGGGTTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAAGAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGGCCNAGGGACAGTGGCGTACAGTCAN
+
*)$'!#+&%(%%(')(%%#!&))&!+$&+%#$"&"&+%$)#$#'"%""+(*%+*+!+'"&%(!(&"&*"*))&&(!)+)'$'$%'*'$#%+'!$&%&''*+&$"&(#)*&*%*'(%$!$"($!%)$)&"()!)($*'!"#'&)'+&
@r4538
AAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATNGTAGGCGGA
+
%%+&$'#$+!$""(%!!'&&+')+#)+%$#""(""+'*$'+*+!)")$''%"*%+%*)*)&$)#*%("&))#!'!+"*'&+&)*+!'!'&%)(
@r4539
GAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAA
+
+.&"+54*9E4&-"1@-@147=6?@/$1'11"F*9@!"BA1@%(5'8C)-.!@
@r4540
CGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGANTCTGCGGCTGCGGCACTTTTNTCCGCTNCAGTGGCCTTTGCT
+
&+%(&%+$+&+'*($%"&(#'#+%$'&')"+"**'+"$&&!)")(*+"(&**""($&)#)$'%'**!#'&&'#%&%%')!&"'#'"""%#')#""&$!+##'"!!$%&''!*%%('&
@r4541
CTGAANGCNGATNTGGCNTNNCNCTTATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTNCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAA
+
#(&%'!'('!*!!)&&(!%!!*!++%%*&')$&+$!"$**'*$(!#$$%*'%"*#!#"+%'%&##$($*#*$$(*+$$)!"%())*"#%')(%$'"($'%+&&'(+)%&+*!%!$$+%$!+#+(*!!%#)&%*'"&%)#*$$"+*%)"&+
@r4542
NNNNNNTGNANNNTGCNGTNTNGNNGCNNCNNNNNANCCANANGTNGTANNCCNNNNTNNNCNGNNGCGNNCNCGNNGNCNGNAGTCCNNCATAAANTCTNTTCNNAGNCNNCNTCNNNNNG
+
#$!!$##"!###"#"!$"!!$!"$!$"##""!$$!"!$!$"#!##"!!!$$!!#"!##!#!#$#!$#$$!#"#"!!##"#"$##"$"!""!#!$#""!$#!#$!"!!#!!"!$!$$$$"!##
@r4543
AAGACGATGGGTCGCGAANACGCTNAAAGATTACGAATTATTACAT
+
)6EG(%$*HHG-;1-><=>1$30#-=07?!@>=1H&1")B"CC1C2
@r4544
NCGAAAAAATCCNNGCCAGCAGAGGAATCNAGCAGAAGACA
+
$D3:<$6/8'5&D%76/=7!1??1@!*!D4BDA,FH+=:)2
@r4545
AGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATCNCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGG
+
7%,?/E+>D/*%@/E3$0#&E==<E%7">2+'70?=5-B7"%E%*-%+74&@:':C98#-9H:=8.$8G)'"D39!*3E#FA"4:E).4B&,CA#A-2E<$,E+*@@6E-3#5E")C>H<F?$78"GD!.%D;=A1F?#3?7G'+2-4&?,%7,C)4=E;*B@'#)F7G5-?$B6(+@,B*7#;8+0:A8F2*6E-(9HH4A1@7/((!G=-!6!,16$+1$.E-F#,A>59!@2/?;;%/E"*B%="
@r4546
GCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACC
+
.??*4,EF#A,(@+C,(-/?FA9>$G'2?,%(F:4>A4+GG1D+@40;9&-<=04@"5"+'5H#0-4(!)>5"'="=17+9E<=<,8A2'7/>F+7DG(3*17A%!&-4>A($F-6:#7955?8$;D9(0B)'.*5+18C'%%61$!D>'$!>,'21=%)E$*7D;4)B6-(#3#1E/3=;$/+?<EBH#=1*#=<)17'6;2D=0A
@r4547
AGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGC
+
H!0?@41.46#6A+;?8;39*"=H;7E!018>@C891EC/?640D7)A5)138*"-5:&=7-E*$"5;%,40%)F:CCBG3)&8!(2@.F$*5!G%%H.7?)%
@r4548
TTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGTTATT
+
='B>-@47+4:5-"47+332#.7$;$?=1EB++GC1AD54@#4!9"-C!<GB+(8BC-9H1=+.3;381<>?)-*8/,9%D=1'>B3CB
@r4549
CANCATAAGTTGATGCTGCAGCGCATAGCCCANCTCTTTCGGAAAACGTTCACGNCGTATCCGCTCACTATNTTGTNTAAACGCCGTGGTACAGCGGCACCGCCATCGCGATTTTCACCACATCA
+
%%%)$)*+%$$%%+$'!)("*#*##)$&!&+*%"$%+$'+$(#&#((%**)++&%+#!)*)**#++)))*%%(+"!%#!+)$%*()#!&&%"++%$'$'($(("%&*#'!*!'++##*(*%))+&
@r4550
NATNANNTNCNNTNNTTNGGCNNNNNCANANNTAGTGTTNNNANCNNNNTTGACTCTCNAAGANCATNNTTAGNNNNNCTTCNNNNNNCGCCNGNNCCNNTNANCNNNTNTTNNNNCCNNNGTTNNGNCNNNTNGNNTCANCANANNNNTNTNNGNNNTNNGACTNCTANANNNNGCNGNGGCGTNATNNTNTTNATGNCTNTNNTTNNAANNNNTAANAANANAGGNNNNTNAN
+
""!!""!!##$"#$!""!#"#!!$!$#"#!!"$!#"#$#!"$#$!!!!!$""$$"$#$$!!"#!#$#!##$$!"$#$##!$#!$"!""""!$$$"!""!"$"#""#$"""##"#!"##!#!#""#!!"!!#"#!$!#!##"!!"$!""!$"$"!!$!!$!!"#$$$$!#"$#$"!$$!$"$$!###!$$#!$""$!!!!##"$""$"$!$"#!""$"#!"$"###!!!$$!"$#!
@r4551
GCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGAGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGNCAGACG
+
G%G=5E7G.ED5#81@A'E-=G$-@5C66+<H36!4+E9*6)/>1<-<3D0$A,40H7&B)?*/.A+1$1=-;8H@#(5D=3>>HA@*=;<7'01?24"?.CC+;!,)8"#BH%47GFA1G9/A&6070;G4.-)"015D8%1E=B61<F.6H?9&-C#'280$0H:'123@,F?=59&4H+C3!G?+!36*G0<A,+A<6E3$97<C"37B&2G-6.1H.?*9>>@+!E#)-?.A/3A;A
@r4552
TCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATC
+
-6G6CH99GDD=.6)";B;B/47@#%H.;-H?/DG8<*/,#'-1440%#G;*%)=>0;4
@r4553
ACCCAGCAGCATTTTGTAATAACCGGCACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGA
+
#%.5@@7)4=!28!><5&)?%1.G",-@*408G5%,8*BBE1B!10C5"77/8>25));)/%.?1%E983#2<>A*'?C%!,:D/-
@r4554
CGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGG
+
B=)%>HD:4&;7?2)D$/17,(,>@#@%1?/*D,'A.,09++H6G>:@"FF@E",?!"??.>6A6D-D/9FDH+G4:5=D@(F2$>H3:;/$6
@r4555
TGTTCTCTTTCAGGCGGCGGGTCTGGTCATNAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTAATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCC
+
<H>-7#7@&G/>$E99:@-!D(G/A5F#%>D*5CE8&AFDE*#26!'6(G+*?.4&(36=FA+<D=859;A"D'7(*C"-8B+7=58@D!1CE/748"(>A.9EFFD#*:!"C38*AH#0*H+:?5.7520?69F$4E859"6+GC7;"8CH/G*(F*2'7>/6;73"EB&<DC2$7D>1;33:4@#;#'C"<)#.<3EFHCDBC0>8&.23#,7:;4?+79!D&++)$#<FE687D8:+@@,*H
@r4556
NGTACGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTNATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTTAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATC
+
$2%&?--61)A8"':#88=B!73@*&A%%'"=F'7121D.6:3:6H,'%E7GE+8,:5D5.205;,C5C*F&..$C:.55=-,799'/5;9*<2B$F%C58:-%'%0>$=3-C*G'$/27'BF!2.8/.7E6$?)$A/+/.;D-'1C&3/%0G#D#"0D%>'$-(+H97*/(?G9?=.:!+F.(2:>=();&E&72/>HD$3D'1&C!>B"2:6AA7=H&HEE0%63,A!9/>C#"$(8&6%&5@=77?;F07/80B.#<5>0#E4;%%5&.A@*92:CF!.$#<!A629$'#G2C528(1!$0"8*62;C5A,
@r4557
CCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACATCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCC
+
1G&:98"8"""10=4+#/<A4#*:(!33@2B%@D7>);(+*H4;5FA4(G5-73H#8=,";>5,8;9?'"A#=3F73(118;'G?=D,1*2?8*4=
@r4558
AGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGG
+
>6::-(3,.59;'=<<-=8+/.,,5#/6BAA21=H;;3=7-4@$F"96CH&(E!.D9>64*:'.926$<'*%7,H7-&1DG&-F>=?DE6:!:BA&E.D'38A94"%B68.@<'&&E:))#?9
@r4559
ACTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACAGGGTCAGG
+
"F18A)'F:>8=-/.-/'F0&90<D4!52+:DFGG<!>G!<,;?+7B.B.1:#-8),67?4?60/%<(::+)7%3CAB,!@88-&-,F4D/1
@r4560
TTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTG
+
;$!$0$9+A(DEF1>#".A#;50:31-120&#*1)3//+?4--%-"F%-3!7G7':C+&GE!D@?9&;H<!B
@r4561
CAGACTGAAATGTAGTCGCGGTACGGTCAGAAAANACGTTAATGATAAAGACGGGAAANTGCACGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGANGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATAC
+
"$%+')%"%$$*#$$+"&!&%#(+)()$)$!+)(%!*"!"$*%"&%%"*&$+&"#&$"'("+$++$""&!))$#$&")$$'(*!"((#&')')*"'&")'%$*(($+''&'+*#*'(&$")!*$+!)&("$(")''$*$$('$&!'!!+
@r4562
TGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCT
+
,H,1(9H-A;'A(@%6@2':2+%@E6;+:E?*(./%0C%/5.('G74?4
@r4563
ATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTTACAACCTTTTTAATTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTT
+
B(@H"@@$C5*+H8="9EC1G>33)4('2#+8=DE$@#E?!$/*E8**+"D?)=9(*"/=%"H8!EE(-5;F:+A2#!..>C0742:@(38<4987C-B&;C2./1(D3>,%:>/;#-1FE;)2B46</!6G(6E3:"@6=B#;
@r4564
CCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCC
+
>552=?+)6;B5#A.41A='&2?B)=.=3!16B!?75!21-.AG:,*%0!.#
@r4565
TCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGT
+
G9.!F;BH<,GA*=H37=5/?4".7&?85D3H1>!&H>"7>/,-'<,,@-BE7*%#,&(3@G-B>B;4+"4',=90.BG,B4,044A7<=-4!)A(;"%CDF:<5:5<#+(%-
@r4566
TNCTTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTA
+
%#!$+'**(!&((%*!"*+#%*&('#'$%%&&)#+!$&#%+'!%&)!)!
@r4567
TTAACTTCCGCTCCTCGCTCATAACAGACATTCACTNCAGTTATGGCG
+
%,?;=0(:&@19>(+=+EH5E;FF*8&(+2!<B78&6E+F916*:H%)
@r4568
ANNCAAAAAATATAGATCATTTTCTTCCTATTGCACNTTATCCTGAATGTT
+
#%!((+#!#!(+)("+$)%%'#%!"$""!"((*!+)+!$$#*$*+&!"#)'
@r4569
TTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAG
+
<$)0#&A<9?09A""@457A93'1/:#DH=/'#0H+4)+'7E7&
@r4570
TNAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTCCAACGCCACGGGGNCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGNAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTNCTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTATCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCNACCAGTACGGCGTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGA
+
$$+'%&"#'!+&"*#&!('##)$"#&+'&!#')'"'!)!+!!(&$)!&$'$!)(!$(*&")!+)+**)""!"#$'!+%$$!%#)!%)("!%"+$)&$#&)%%+*##((*(($&+!$((($+*#'(*$&(+"&'&*'+!'*'%#$%))$%(*+*%!('+#!+%#&%*%"$$+)*)"&%*'"*"%&)%'%)"*'!#("+%&$$+&!+$($("("&+"$!!*(!(!+%)!")*("%"+!$""&!*))($($!"+%$!%'("!*)!&%'$"%&')"$!"**%#$"(()#!#&&"&**!%(((++"!*(+*)%&(%)$+#*!+'((+&($*"&&%%%&*&&&"!!'+$(%)%+%'*!'$#&'&''*#$+*!('')!))**!)*+%)"$%(%$+)!'+#"*(+*%&''!('##&%!%$)'&+%%+&!*(%'*#%&
@r4571
GCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAACAG
+
$34#?G>CA*>,8:@<C/=?28H8(;8:1#3#01<:(6"A,5*
@r4572
ACGAATTTTCGCCGCCCCATAAAGTANGCCCACGACTCGTTCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATTCCGGGAAAGCTGCTCATACNAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCG
+
2C;6%;81;&#=#.0F0D&>B$FE7GD@*%0D;G536B!A!.B@/F04/7(?E$?5(8./.G)E)&5=+0'</F4!3B+5BA3@7B)G@$*1F7%8+80'B=9*<D+*H').(@552-.:6D>80@/>*181)3@&0++DAD,3!+$H3E07*7:,>,<1G%
@r4573
CNGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCGAGCTTTCTGCATCCNGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCT
+
!(+&+(('%)))'&!%#!%%%!&$**())"(("&"*#')+"$&"*"'$&%"$)++()!#+'!$$%!+'#"&&")*)$!*&($&!"!))*)(*#($##%%+$)+&()%""$"!'+$'"(%&+*+)
@r4574
TGGAAAGCNAAATCGTCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCNTATTAACCAACAGTTCAGGGATTAATGAAAGNTGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCA
+
)&#'$*)*""*#$($'+'')$$&%'#'(+)*'&(&&"$"')(($#!&'!++'$#%"$*#!*%)!)+&&*'%#'+"%!&&)'%'"!'+('$**&%*!)+(!'#**!%'(!$($$*&!("%&))%#%$)'&"+&%$#$###!&")$"(($#*%%
@r4575
CAACCATTACAGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCAC
+
=/A"(+F+%:-E(*&25!:/80B-((4@#5$'A#F$2A5+7-9?#(,6G<DF?B7C(+'0"@):)*D(+#<0'-+:5,&=8<,2!$5!"6"56-1
@r4576
AGAGCGNGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACG
+
4+C56H:@'#?B&<15E#B8(,F"#900A?4*4;D$$H)"0./)A(>@#6%/%1(-97<A3.+4:2B+E6)<6!>&+<H?+E,/;%7*75<)%!</GC*,F1>,H-1,$<C,)6<%4*-7):BD#$H7DCFF.@+E85ED0@:G*315F;#FF3E,<:"-H?GF7CH6<#1<##B+@2?#(
@r4577
CCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAG
+
5(C<HA+1,!$HH;91.HG>4*?.$'";D+A=#6$;2=120BB((
@r4578
TGGGAACGTCAGCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGANCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGC
+
AC<G6&#!BF+/6641&>2$716%FC-(,7973:$+)98%<?,5<BH#98:%6)AG#GAC+4HG3?,C@$:6F*=5B:>*@;2.&.>*<+D51FH0GE6!"14?(/5+A,D::
@r4579
CTCAAGACGATCCTGANTGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGA
+
H(#5AB8<(C"9B4$=">DA(!1*$:!E/F%:>:&(?$<B<:.10CCG;'(>#E,+F(%03H?/(>*5.+">!))5DE@;@:4HH@=@%2,H>$!E++D/
@r4580
ATACCACCACTTATTATCGTAGTCCGTTGATTCAGAGCTTTCTTATG
+
CB7F4**A3>F%:B65,,B"3,($E<1-@(06F2('99@<3H7F)4F
@r4581
AGGAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTNTTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCCGTACAGCCGTGAGTGCCGGTGCACATGCGCA
+
EF4?=C0:(&?8)2<DF<>:G"AB@64E<;'C<6G6>!@>4H$/C")?*0/)>1".*!H"#D':G"-?+(!G$$%$6F+3@C.D5)6,:'A42C&3"@21=&0641E=2A6<49+)="+>*9AADD
@r4582
CTNGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTNGTGTTTGTGTCCTAAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATT
+
&#&+"('%)$+%'&"!!+"*!##+%*""+''*!#&"$'%"!+!(#$)+)'!%$+$*!!(+&'#(($%$**!#%%"#("%$#*"%*%&#''"#'()#!&'+))'""%%&!+('%+$((!*+$''#!!&'%+*!+"&
@r4583
NTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGC
+
+@?:B)')!1%)@"4G%G"04H4)6?'/D;$9%8$.-)'<06
@r4584
NNNTCCGGGAACGGGCGTTTTATTATAGAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTNTGCCGCACTTGCGGTGACAGTCACTCCGGCCCNTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAAC
+
!"#=3%;D03G@(.6D59,:-!=!.DFE4/*C)&?B%#DG"$3/F#)+'06)B<+4H<;3!49933>B$6B'C?@87%<&>"?F<D@;7(BHG.F"!G&=@"-!46F>)G%4!9EH8E$97;C09)%*)#5%(4@@!@H<HC%%@1D?6HF.*D6D+B528
@r4585
ACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACG
+
%9,!;";H0+4$-?8%.F/C?,@$8F4/7#G@6'@H"C%@6#+-(%81)CF<(%A+
@r4586
TTCTGGTGGCGATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTNCTTACCNCCTGGCCCACG
+
+"$))$)++$&#''""$%('($&''%'(%''#$(+"%+$%)#(!#**(*"&*(!#)%(")&++$(())+%%')"+)'"$$"'$*&%"%&%&*!''"+()%!+*%+*&)')
@r4587
GTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCTTTTAATGGGGATCACCCGNAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCNCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCGGCCCATANTAATATGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCTCCCATCCCCN
+
,;F=(95!/@-*1/#B+4?'!<4+:$H"4E0@"0#0%(.<:9A;AE='436!;GFDA;B8GG;#A2/#%;+54"G-,<5,>H=D81,1-"8**:6@,91+-D8>&#@3(./*G@A.@"F5.7HE,4).HE95%'*G/FH,$/<&@1""<#6D7+/C"/FA@"(2;CE#!*1<@3(1/$%;:62*<GA3'#717!C@B"8G(D3,,44+8FA2"A9!H/,;"$789A:1%,+9?C;,;/:!%,,18E$50$/->/A)G</(G2C8:+(6740>A-C,2==/70!',AH39&.<+17%+(67B>4E*G>$-@;H2"!B7F.7<#?HG(
@r4588
AATANNAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGAT
+
%!#($!+)%!$))%)*#'%(')("''$("$&%!*)%+(%#"'$)'#&
@r4589
NCACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGA
+
('C-:;$#88>D391+%04'".'E&G0!+(?',"FAF")#@CDG(*4?)&%
@r4590
TATTAGAGCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAG
+
(*<2E(:.6*2+9$=1778H7#-,(*&%;<(/8/&@(/='@>;.D+*!$#5
@r4591
NATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACT
+
451.8A@'0.7,&GF5:-=9E?A>.E"B0HDA:)%4.0$9DD=GHG+*&=$67D%,CC&+;E/)$412(5
@r4592
TCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGT
+
;65)D%&4(#?%*;7?-!57?7(6*$2H*:"<+D7-3!.;+E,$074(*<F"<81E570-;/<H4=,$G-*G"@B4!/<)CD#6
@r4593
ATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCC
+
5CB@1E>8C=D52(./CC66*5HG2;>F2GB#,2/AA$64.B1&/
@r4594
CTTGCTTNGTCCGTGCCTGTCGTGGTCCGTCATCATCACCGGAT
+
)!%(&$'"))!()%)+*(!'$"'*)*'+*!)%$#())''*&!%+
@r4595
TGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTNCCCCCTGCATCAGA
+
8:/@DB9"6'HF6*"B/!@$.<6DF.'(77;E,20A&<85:3"90<=-@(/:=2"*#+%!E7?;@?@*:16B8(
@r4596
GTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATNGTTCCCAGAGTCGCCGGGGCCAAGTCAGGTGACGTATTCCANATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGNAGCATGGGGGGCNGCCATTGNGGCCGGTGGTATGACCGGCATCCTNTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGT
+
6*/B1G"48(BH"&4&:C)$;0;)&)>?5B+G4?)CC.@FEE8/,46E@#:5!B&$DEHE6>&.@A792D#-")*#&<4@H+$#"8%#5*F316/#)*;-:'8C>B?@;*)A&!7:'5DG3",$>+35H*9,D"8H+H@)872/;G&@D.-689'*1C-1@3;5)AFB",445E<+,@>10A:-9*"D7<.>1$CA7CA##*7C1%9/;";"/&!#81+;B*
@r4597
ATTGAGATGCCGGACTTTCATCGTGNGGATGACTGGTGGCGTAACGGCC
+
8/8.;-'&:'4@9>)2??#?<';$F6A2H2?:G&0@E1:=@A=E.-?+F
@r4598
NANTAACGGNNTGATATTGACTTATTGAATAAAATTGGGTAAATTTGA
+
'$#*%*'&("$+##+"'&!)&$+!%!)+!'""!&##)('"*#'"#!"+
@r4599
CTTATTCGGGCGCAGATCTGACCAAGNGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGG
+
;*G%6GE#2E$-4&E0."("HA(F4H4$,,.D4<166C--)<'3&F,2G.2&$%?E/H0G8DG>CE7C!'5,<7
@r4600
GCGGAAGATGCAAAGGCGTCGGCTATTGAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCC
+
<.:)66A1/1'!<H*"H+:<AE+,8D8=;$4;*$G3(.H+$*>1F7BH-;;E,!9F0+.@-7DFD8.,522#<H/:B5*/6!?8(HH-F10,9D6
@r4601
GTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCNCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTANATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCA
+
C0-')7*#8H5;-3*34#?;@.(4G@/7>C*"%*?/2*(EH<(D?B>$'%#$*.'>39E&6,=2&;2=H5A7/>9#C6$"+(<EEHC<9H1A.*82>33$F9*@?%";53+5%"9?)F5)*HE<"37>*"(=76#%64E.96?13+!70%;"/9;B
@r4602
ATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCTAAACAAATGAC
+
E78:8$%6:,CG>7;"EE3C&C"4%0)*E7+#GBA-89G.>B=A9AH>1-9$!G!G
@r4603
TGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTC
+
C2&F"2>7B9F(9H+,@>,@4?-,??5$$-30$4!)4C'F>6#$')2&>/'56C=&D?.&7F<,G3?$E915:E0.$C"(;H<<!3!:5$:7#8!?8&DA1++5:8*<
@r4604
AACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGNAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCANGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCT
+
&529HE"D:*$H:!;999/)7(6?)'%5CF>D87B8>*"0FE<%"$;C)!$,6A5-5!+C/H/@8<D/$9=F'*446D3A6D:HEHGF:-D(6*?=?4GE%H6*30-D087G&<>A1-:)(7&/B$F73@$*+!9@?B)H0(?@#H>@>;45$<17&>FDBH<52=1!!'8@8E#'88'=E*;'G@*."94'(>$@0D5"AF6;3$?G*H!?;%'4D/?<D+<4CEA28HD:92C(=A+89D64&"%&)7AC:=E0-C<G8C18+..<62%<B64!@:/2$5E722.$@#@7@?C60-2
@r4605
CGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGC
+
>.A3+0%E7*=B9@$E.?'FCCCG71F"$@,BE7((#0)>*+3B!1=7+:<(B,""9(-757D2
@r4606
CTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAG
+
8#05&@D11?)E@&A-*A:9<:)3'0;92)54+A"+E4C(-;&.1(/<HE."&2;&E#+E85A,
@r4607
GATTCGACAACAANAAAGACCTGCTTATCNCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGA
+
A38H5;!2$/<92-H6*8&E+%9#FE5,$G/3B45;B=5H38G3(F381A*##"+()H/B@;6
@r4608
NTGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGANAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAA
+
%G*5.@+D/7:=:>(H:>?F9.(10-=!1,9E$299$./&'$?$*,&C#DHD42)#-&'A)GF.+@?BGF.&B'>2AH,6(:F.5)?&<!(=#'FC:<84?<
@r4609
CNATNCNTTANGGCNNTNATANNNNNNTNNGANNNNTANGNNNNNANNGTGCNTNTNTNNGNNNNNAANGCTNTGACN
+
$#$#$$#"!"!$$##!#!$""#!"$!!##"""$!$#$"!$$!!#!"$""#$##$""$$##$""$$#"#"#"!"$$$$"
@r4610
GGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAA
+
"H+1A1'FH@4+?GAA?5E--H3/+<#,")4799:;E6+>>0-&F":0A';"A*!*7+&E?F:01B+H*%<(?F4*?<0<=@7G7$/:C!1$99:.*(1C>1-@A9(;6.H3&E(2
@r4611
CATTGCGTCGCGTTTTGCTGTCCCACAGTATTTTTTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCAGCAGTCAGCTGCTGCGCTTCGGTCAGATC
+
63F/)C5)-F*902!!4H:!./@:$D?-#?3A&:>".D4*/CG$21/=5&+/>/3;"&&?,GF:<6(DBC;34.A;BF1&,?6!(G*,@)@-<3,(7,!5
@r4612
TTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACGACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTC
+
=B7G0=4&44D#8B?/,&G5>>F64#H0?C:?*2**>5FG3?1(.25C>'G(G.&D1(4A4B=&AD"-C)/A689+06=%D8D(C-%"=E1-7;!7A,7,6-<B$:@+A0-*!H<5$-.'(*H2(*84AEH/:"1-3-;*>A5/'#G+/2G1@:1%$4,&%>/6(6$A2A:69D80,/)%;5:3,$;;)45"7H!+9-@!B:F5F*;!(&1:C';&?63=:60*@D&0EGH4-A5(?9-6"7G0*$>%C:@*A!8-&%8=G11)$9;)D-!FE)GAC6E=#'$':>9DA<;$;-,#C+3@7
@r4613
TCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTAT
+
$,='/5(F+A$C#;&E2EH*(+>F#.34('+3#(/4'.$8,6:*B+&!&B3&34G
@r4614
CACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGNTTCTCCTTGACGGCTTTGAA
+
7%'#=*2.&>?6E)@,1EA7""H=;,B9F*'B4?CH8$D<7<.&21A)".B#1>%0+EA#4+@-:1
@r4615
AAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGGTATTCCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGATCACACTCAGCAACTGCGTGGACTTCAGGTT
+
$CB,@A2E+8)H.+@>-?@02'BH#C@7H;DB="8F$!/=EA?&!,72&)H7;1:E@)%G*()(=@;6$,7*A$/3)&8'7$DBB'(GG6GGCB#%F@F;,2/,-E=D5$,<G*,-2@69%8A>!F5GH(%-,>6*/;&0'#:+5'.7F4'$E?0?"5G/B+*D4B&%:008/:$;F+C8:521/-)FH@.:9(.G2&!3E0CFG+F@/<0*7#D>/A27C89"B*A@);;>@A/0.?.#E9D+0,$+$=@G)86'4&<9)>0/EE/)%B@59$ED0<'*;C%;GBG'>A>C(#-+,7C8
@r4616
CGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGTCATCNGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCNTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCT
+
0>?;.)2!F..7)F:;:E-0"5A(.>(#7!#D=("-(1'!8=F#?&$8%E,'C1,3<%7:A&)1%-=6"F.)#::/@G>G9=45H)ED517GC34+?%'9=>>8/#F0-0/896=)-$*B$'#*E'B;,@9F/F4!*&$=/49>0G%@,/=7A$D54G&)7
@r4617
CAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATNATT
+
7:EF27#6481@C7%?93&FE#:(9;$9+5GG!">3#GE62,+!E0-4?B;=F@&-57,;1%5F%HH9)>#FF,A*#))1F,2;,!))".&>+=A
@r4618
TTCNTGAAGTCTGCATGGAGACAAGACACCGGATCTNCAC
+
?3C)=<3B!(--!+-52/433"?/$(@@6</=*"D+';)D
@r4619
CTGTTTTAACAACATTTTCTGCGCCGCCANAAATTTTGGCTGCATCGACAGTTTTCTTCT
+
5+3941=8""D#=19D=#C@#?'@#%A1F8$FB#!-,6-B0=B8,FD!::&/++=1:B4F
@r4620
TGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGACTTGCTATGTTTA
+
=>71G3FH/*0CD2.609;=$G,$A<3:DEGC!7H><!79<&1:-;-'E5@&5@91.38F6(1E+8>G@7!/%;?+9=4&!:F:=
@r4621
CACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAATCC
+
G$G@0;:$C@9#C')A##5,3D7,#"(D//>:(+F50@<BE5%$39H,77&6
@r4622
NTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGNCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGG
+
$38>0<BD$6D$@-:"*.)6.4H'0&1;943A4@%*H@8G29C*%.:->B5B8';08E&A%"'A.B'6%#35FF&3%?$A(;E5:<&+EB??>?G0@AC<*D<
@r4623
TCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGNATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGACNGCGCTTTACCTTCGGTGTACAGGCACTGGTGGAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTC
+
<)$(0<+!97H6$DF"E=C1E7+71&34C2!71/=%?-F<.EG*/B894-(&1.E6"7??-EBA/E>'E*338+E@,E7C&043-HH?93'2&"$+1-*9CC%8/5(=AGDC2G&,A(C56:GA?9$H!<1,>F52:+/G5C%F,A$7?E83?-;G>.!=9/%F>H96/*B'G,B7C%@;E2FB-!-'7A8"C4/%#C6@#E37+9;@E-H"37=
@r4624
CAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATC
+
>,=DHC0E"6!%>"HH92!0D39E28%:&++7):!B@%FB#:D12"!:805B%
@r4625
AATATATTTTTTGGCGTTATGCAGCTGACAGAGCNAAAATAACAAATGCCTA
+
GCEH);<=7.@-D?"$C&4.7"HA*H9@5-%7%<5?),+8*5&82'G726?'
@r4626
CAATTTTTTNNCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAANATTTTGAGCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGANAAACTGCGCAACTCGTGCAAGGTAGGCGGATCCCCTTCGAAGGAAAGTCCTGANGCTTTTCGTGCGCGNATAAAATA
+
&*#%&(&"&&#)+%')#*&''%($"!$&$*'$"#+("$$$)(*((&*$!"*'#!$'$"(#''!&("#"%"")%)&$*)))"!""+(&)''#('#'++)$)'&!%*%&&%(+"%&&&''#$)##')("#(&('(*)%"()&&**('&(''&)"&%$%%!&%&))&")(#)("")))$($"!'+(+%#+*')'+"**#*"%
@r4627
GATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGNAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGA
+
G7H"5#-+*-;(35CA=C6%6/$%;570?F(G-.,A)A>A8#.,AG$H.=AEFE=D5&@'@7/$9,9B-@EEC(3(D.;;!9@2/)A#CH5A*46;4;/("HA9)'*F0A@$<F,-+*&.&35D8;%:GF"??@(*31CF/&E:)6*,8;C+0+6;&7:-%(
@r4628
AGANNGCNGNNTNCNTANNNCNTCNNCNNTTNANNCTNNNATNGNNAGNNNGNNTGNCNNNTGGNNNGNTNANTNGGGNTNACANTNTGNNCNAANAGNNNANCGA
+
###!#!$$#!$$!""!!"!!"""!!!"$!""$$##!!#$"$!"#!"#!"#!$!""#$"!!!!##!"!#!####"!!#$!$"$!"!#$$"#""""#$$$"!!$##"#
@r4629
TNGANNTTATACAGGCATTCGGTACAGAGCGTGGCGNTAAGTGGTCAGACGAAGCGAGACTGG
+
#!))!$#++&#!"*#&#$+'"*)*&('&!&+""(!#$&+("+++$*)$%+&!$#"'"))+&&"
@r4630
GCACGCCGGGACCATCACCGTNTATGAAGATTCACAACCGGGGACGCTG
+
"(5F%1(#'(C;2(!;5A1+:H(!+@GD'!42(4>!3,D@((,;$82#1
@r4631
GGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTTGCCGGTGCG
+
F(3?41EEG>;%&$,$F,!1!.;46-(74>E:97>*1)"/6-$-*>"5C%$10DG")3DFF4
@r4632
GGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGNGGGTCGACAGAATCCATGCCGACACGTTCAACCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGG
+
7%2$@.%HA1D*1E*<3>,6<!36$-57;E".F5*#0).A7;C4!B'529''**3!"7?5/--9E30;&03GH72D@93G!3'3&>*.*H(?/672,"0#4*4:H=>>4C5B(AB.D%4-224%*0GH.=%)-F%:D8.2@F-"":;=1&;+/(!",0.+E&3+B17@B5%)=.-,6=D.?A:(C1)<@$+>!#!@-%"3D-=6)E!0%29(H?(CC8+0EC&;+7,8"?/"CA'>#9>#E'=$6B>42CA<!$A04H=)2*!&=H(?$@H3':AG!AE.91CE6-"13<6'3#-.$!338!)3').2133>3#@/4+,3A+*>D-&,F#=#%:%")%/<9>G,C4.H/>C*=0G7%E@/6<@G8@#"4,?&7%@15H$;;%E,%44B?6,B<-3>3#4>37$&3*"@;<:FD!G.>D#(@CE1#'-98:%?90:.B><:",.2*2/".<F-
@r4633
CAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCN
+
HB2$/>89H9%"8:8,'@!;D,G@:B/80%:$4>))/F552%#/#>?*G?&@2
@r4634
TCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCC
+
@F7<4C-%4!<;A:+9@8<#17;%@*F58(2:D-E!"37>
@r4635
CTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGNACGTAAG
+
A096E?=DB&:5.+/DC=B;4;.)!G:)1/D5D)":4$?<<:)$,'AB:H:(64:"+*@$<-"+@>1B-40#,7&;7E/32''7*.H(4+1E>+6#)H#+:E9#=>
@r4636
CGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATT
+
(H1:%1&H>''1+3H/3&70'F*4CH#/23;6'(8#/G2A80<+6G?1:?+'5#0"(,:;)7(GB690H="AE"FG%9B)
@r4637
GCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCC
+
2D*,.GH)1"=99$8*4=5'&%9>+%A,B&6$A+98.A#*&"B;?##'1<#F-84$A#5,;B9"3H'./+H$!$$H>7-
@r4638
AATGTAATACAAGNTGTTTGATCTTTGCAATGATTCTTATCAGAAACCATATAGTAACTTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGC
+
-:A?C.029;<"AA87-*79-%,:H-C&180,G18-H4(&C)50::%#&E+1-81#D<,E:744@6&5!+<G?F+<E=AE3B-"G=ED2'3&.'#/7&@>B6:9.G'4F6B&=A++468=D*-F$)-D<>CB//<"&/B59>BD&3?$/@E*34>=5F4-C*0(<0,DB,A1@)6%/'B!@@*/>.$"A.&AB*A*8B!"F
@r4639
CTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCG
+
>F1>(1=7"+EHCB2BC-G1CA40#A35>446.64.&(30=)B.
@r4640
GAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACG
+
'*>A(!590C,-G0(D*/)'?CD*2B2.AF62"D40)@9:
@r4641
ATTNNAANNAACAGTCAGGTTAACAGGCTGCGGCNTTTTGTCCGCGCCGGGCTT
+
%&)"(%!(#+)'&&*#+#+%&"%&#$)!!*)(!$&%$%*)+#%"(+!++$&&&$
@r4642
CCCAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGC
+
'(!%%+()(+')%!#&&((!!'"'!)!"+)!)(++#(%))'(&+!!$$***%'%##%$)*+$&+()(+)#*&*""#+%&'!+*+&$$%$%'&("+'(+**
@r4643
AGANNNCTCCTTNNTTTGGCGAAGTCGAGAAGAGCACGAATGAACCAGGCGATAATGGCGCACA
+
($%"!!(%#)&#%"("&+&#&(%)&%"))'%"&'%(')+#+'!!&!+%$$**'*&"(*(#&)#+
@r4644
NNCANNANTCAGTNTNGNCCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTNCAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTACATGACGAAAGATGAACTGNTTGCCCGTCTCC
+
!!('!&"#&")('!'##*+"%&!**&+&#)+&&)+%&'$%#%&&*&(!"%"%##"()(*(+(#')")&$)$"'!%!%"!')'($'$!(++!)"!**))&!%)(#+(*%*+*#(('*++%"("($!&!'*&*&$)'$)&(!($)*
@r4645
TGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTACCGATATCGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAG
+
D?:<$)H+'%+5H+@82H,)?0'"$<23'!+G6!!B650%$80*8;%<)F)5#D+2@H)F?+.=%>C(.B>*#&-<9@1F'%>&FA,9D$%?'94;?(*990&G/=)E-HAE3B9?/C$-#!?60EEBA2/H&#$/#:)BB('@D2B(D#G937/=0G+
@r4646
AGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGA
+
C"*DH3+)&3#$2?634'&D9B=92+36E,&55%957*/1,&750?HCBA5>6-0!048,?CC*!/'22;F>=A%
@r4647
TAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGGACTC
+
"=#:%#E1>>!>-@5/45>!E,A:56F<("%GFD=:%$>-)F929#
@r4648
CNCCANNCGGAGTAANCATCANCNTTAACGCTGCGGGTAACGCGGAA
+
*#!%)*"*'$)*#!'!)*&%)%$&%%*)+!'++**!!*$"#$$#$!+
@r4649
AAAAACGTCGATGACATTTGCCGTAGNGTACTGAAGAAGCA
+
DHDD39&%2)@>)DA:DC!51>+1D/$2-="+.!CD26H96
@r4650
NGAGGGTNNNANGTGAGGCTCAGATNGCGTCCATCAGCCAGAGTGTGGCGCGTTTC
+
"*#'#*(!#&#"((+%"**'#+'#$!$#%+'('$%+$&")%%"#%)$*%'*++'!!
@r4651
CCTGAGGATGCTCTTCGAANTCTTCAAATTCTTCTTCCATATATCACNTTAA
+
,*3B!74>=>+(5HH%H6":9GA3!9G/#C!%E8<@A#6G/F(1D#8GB:61
@r4652
TGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGGACACACCCTCTTGA
+
DH#)B3*,7-;(,C5"98")><<:/,(88&A(-C20G+8.E/";-*%%GE);6"$9@@/%CE/3',5+B&8/C!")B.3;86().<(9<3?H9:*.5>5H"FCA/)B=0?"@'/
@r4653
TAATATCCGGATGCACAGGATGACGCCGGACAGNACCACAGACCAGCTGCANAACAAAACGCTCTGGTCGTCAT
+
%0CG0?G5C&,@D+C+%D"3/0:HC=#E;&'3=+A1)0#,*/(<FG2H(&(?5.!D%;'7,B;&)7F:H/-963
@r4654
CTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAANACGGCACAGGAAAACCNGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCAT
+
&85F:*4,;5C3@$!2-BA/%-%E81+$%*:46H$*0;BFH;-%(2B#,E"**3))0"@8E58D=D>;<H0(?(6$G>8"*!,0HEH/.@<,E'7<)@88?.A(H=1:'B2H8)52*:/16<B3@245DB"#D:$62D;/5>$=*1;).$0D.*?",#G(>H.=,"")(@EHA=B@8C1<3<-!;!B&49<E$9$@3..$
@r4655
TCGCGACCCATCGTCTTTCTGATTTAATAATAGATGATTC
+
,7>5%%/AH6&&-2G$4=D%%3=DE6.&C('&-F9$!C+1
@r4656
GAAGATTCTTGCTCAATTGTTATCAGCTATGCCCCGACCAGAACACTTTGCCGATCNGCCAAACGTCTCTTCAGGCCAGTGACTANCGAT
+
H-&*07)$6!F905"/<087$7A0%3<'C'+0"0D@'G>E*@-86&$)'06$D1#98?(/#"EB0B$'0H!+9!/FE5D:H<'"/"HC$.
@r4657
AGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTNCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTCCACCCAGCGAGCGGAGACGGGAAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAAGAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACNCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCANGGTGAACTCACGCGCCGGATCG
+
&AD23:GC&/GG/6@;GB?$B6F"H;>,26'#-25D-?'H#0@&<$30,G!!*'.(:/C5F03439/6":);&)6)2>1$H>3-37+H:BA)(-E&+-0#<2*<.B;H!>$E0='$1;)'+HE-?8!+.H.+*>5%AC(DB3&@C>D6G+?G%4>GC:/"$/%C47-5/,6D769;':(E=3!./>@-<'.2(;/!0'2((:<-%)1':8,$;;D67F1<E,"4G7E</3G(/,21/&=;=-A6=;"11H6:%A
@r4658
NNAGANNCTAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCT
+
!(&&#!''#+$(!&)!!)"(#")'"+"$*!#*%)#&$&#+%&')+%$%)
@r4659
AGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCNGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGANAACGGGCGTAAACCTTACGCCGGACCACCATTCCGCCGACCAGACTCCGCATATCTTCCGCCATCCCGGT
+
*,+$'H4F#)@B$&B9'H>;.6=6+9G.>/;/*0&E)A*-!2(-,&5#(G-&D1)A"H!/B;(,B-3#DA-;1C9"(/>0!.$2/?9:3&-.(')%=F56E/70&1#?B>)*/9.9!53.H810A$='1,5=(:6C?;2%(#:2&+H#"#A:%2CE"CG8CA;?::%G-)9&H%/>G'986
@r4660
NCCTTNNACATNGCTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTGTCTGGAGTGCGACAGGTTTGATGACAA
+
##("&#!#$'&'!%(+'+'&($!&#!"#$&#'((($(!'+++&*!)&("!+!&%&)"'%"%()$&'+&!+!%("")'*#$'$)("(+!(*"*))(%$'"'("))*""!)&#(&''!*&"!
@r4661
TCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACC
+
$'D*)(--:!-?84@1=##D/H%=<39%B&CF<8A)+:'F686E<4'!5HAB<1!74!%6$-.,>8G.$G;,6
@r4662
AGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGAT
+
68,"3A>2#>F-<0+>E%C%:G.5H.(,1.-96A0D"H!4"<#G&!9)+&E'+2F0+#>
@r4663
AANCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTG
+
!'#)+)'*##*&++'%*$%&#%'%*&"'!$$*")'%!%)(*''+%+&"
@r4664
CCTGCAGCGCATTGAGCATCTCGCCCTGATGCAACGGCAGGCAGAACAGGCGGAGTCAGACAG
+
,9:009'E>?3BB335""*53#7%)5-0,BE)/E*=$/$,$,:8+.<AA1-+8'-1-5/?&>7
@r4665
ACGAGATGCCACGGTGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTNTGCAGGNAGCCCGGTAT
+
(+#!*&"$$(&&)!**)&()#!!#"$$!$"*('#$''(##)+$*((#)*"!"$#$)%"$"&'%'+&#$+""*+!(($$%!&$"%)+%#)*')!)!($"*%
@r4666
AATGCAGAATATGCAGTTACCGAGATNTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTA
+
;H#5.-&:B)!8H1)9(5?%C90)7>A?%>"C%3,=0%'?@77EB2*8,$>7>FG*?D#?&B8(D.1*3(2CF98<4=H2%;%@%7+;D4<0:#40*1F9C"AB?$)#A:)G?@>/.6&9)0"%@"66F.?!0;
@r4667
CAGNGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGT
+
)%#!%)*&$"#%+!#(!+$'$!$"&')***"$''"'!!''#!$$#"))$'!#*"'#&))#*+"&'#(+)&!)!!()#'*$+*($(&$+&%*(""(+#*(*!(!($")!&!+*##%$)"%*"#&+%+!$'(("('$'!"("+(')(%*%)#!'
@r4668
CGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCA
+
*#1$'>DE<4!C=21-:GB82EC.076F0;'2D(/*2,@>**H.385*9/B9?839;?21F#'F<21@H:*;()%,,$-H(20DC!A$1+@>-',G,D-#&:)E**4))'BB"(:F%68/)+D%DGE+3$'%(=!5A>)(2)
@r4669
AATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATNCTGTACTTTCGTGNTGTCGCGGATCGCAGGTGAAATTGCCAATATTCTCGACGNGCTCCCCCTGTCGGTGCTGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGNGATATCATCAAAGCCATGAATAAAGCCGCGCTGGATGAACTGATACCGGGGTTG
+
6H0>*!$6!+*F!$5+DC=%,&,A93.*3@73BB+F3('B8A?##0(8*BE($:8*2%GH+0G'*/=E3A"*,@)6,E#'759>G@E@.07@<*88A@"C*$)##A&E?B,-7+*%2;C@6G)",%.G>D(#H4#/4+!:CB-"&5GA@/.HF@D9>>C+H7;@H0'&'+3.+=&G&<$=8>3(4DFFC?.%+8$''!,=A$7G8<#&&C&2+
@r4670
GATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGG
+
6*HE98FAE!5A"!$G4),E=31"C/8)8"/).+4&-=<)*%8?=3=3%>*76&&FA
@r4671
NAGTTTATAAATGAGTATCAATGGGTTAGAGTCTGAGNAAAA
+
+0:*B"=F.AC8*<6!$B1//-DA5EE?"A?HC.%FH7F@G'
@r4672
NGCATCCTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTGATGTACACAACCGCCCAACTGCTGGCGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGTCTATCTCTCACA
+
.=4E-0'>:6('+4?68F5-<3*%,('$?@*,9-F=/C<"$#:#CAF-C-<A%8D''+.,;>=<64?<@6BB:*H*@0>1A<93?C=$"9!,)A"=&1;(2?9,50-/+*&5!45@.H-7$E,*A,=&G$0C">+&3@)"1FB,:BDB.8.HC/D>@&$6;"#/6/!FB8?7A#E:(=-7%*"E%H*C"37,4
@r4673
CCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTG
+
()832+CG*D!8&0/A<)B6?AA-GC-C7-<G0<A9"&CCBF/=)@,!$A,477,-"4;-*@=5'7,?*//69;D9;H,";;25)D#@5A/1H3$C%#8*+5,)30+7H;E20:$+DG:/*)+&"3B=A#;+!7'G911DG,=<%"
@r4674
TCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGNAGCTCCATATCGAAGT
+
B1G5C>*6%7$"&7:+B'/43.E#28!0979)(?*055&./C(-C3C=)>@-90;#7).1G-G+%2$0BEE!
@r4675
AGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTANGCCAACGCCCCGGTGCTGACAC
+
E@"%!/B(71!!%C%E#A5(5.52'H7B5EEEA;''7H=0F'"1%$9$,@1*(9H5422%H.0'!#6E&-!%F;6*,<@4(3?4><G/4BD#8.6-'5>9'-F&+#.C1(
@r4676
AGTGGAAAGCGAGATGGGNAGACAGGGCTGCATGATAAATGTCGTTAGTTTNTCCGGTGGCAGGACGTCAGCATNTTTGCTC
+
32C)0)@+$*>1@(1//+7:8@#+46E53*@<D50%AHE!2%:1.8:FC,4@0<)+5G$1(-.%#:1.2"<0%4+#8%6?D+
@r4677
ACCGGTTTTATGTCACGCACANGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCAATATCGAGCAGAATGCCGTCCACCATCGGATCGCTGGCAGCCTGTTGCAGACGGGCGATAATG
+
5>.D&C0A%GCH:>$?C3:*0:.@C8$5>B5,'D+*;,*,6BBH9H$,G%5$*E*!1:6BC>G>$$D$B!)(1"BE;69H:;;D"8B$-;'>,$C:@1+9#!/FC!0-+>E&$29!;0>>;%*0/(/H-29*9-<+"),7D
@r4678
CAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGC
+
'>A8>5:@B:;02#,%(&*5C69D?6'@(3!!)76)A$F8->.7.A@?HEE1;+))CDDCE+EF,/G9:7"8?GE<%A9F'.@?@<1H+#86@<2E9
@r4679
GTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGAATG
+
+&?9@,>$#1*01%A$,6H07-(A%H0;$C=H$,"HG(12"E@7B,A,2GGDA$%<$&.*F$=@3D*.H+*(#&7"E&9<#
@r4680
ATGGCATATTGCTACGGAAGAATGAAAAGTGATATACTGGAATGTTTTAAAA
+
.(5C14'*,)5.80>.?F4G9.882H*9GEGA/2H(1G95(#/1>/!>-AC/
@r4681
ACATTGAAGAAAATGANATTGAGTTTATTACAAATGAAAGGAT
+
:F#3#1:'*+"A;1A+!C&#'6+?A@01;0C;H<.).-B?&:C
@r4682
TAGCATCAGCTAACTCCTTCGTGTATTTTGNATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGT
+
H(-?%*<091+'FG8/;G0"B,?+(&<D=4+#F&EE:.B,D?(FD@/4E@*-(DC1@3<4CC/FH$><.1)H-57'D?20&7"G<;$31##B1.67;G
@r4683
GACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGA
+
)$++**)!#%&+&$%(+(&#'%$)&)$'&*+%))+$*#))#)!(*%)%$"!%")#!$&&(%+&'%!'*$%&&$&+(+$#''+(!'"(('(!&+%%!!%+&''$"&$(+$#(!)$+%+!*#!"*%%!#((%&%"*%%+#
@r4684
AAGTGAAATCNTCCACGTCGCCNCCNGNTNNTNAAGTNNGGNNCNGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCA
+
)'')'&'&'"#""$%"!!'&$&%($(*")!"*%%(!)((*$!%'")+)(!)$'!+('()%)!!+$$*%#))%**'%%"*()!&*$"+%!!!'++&&!''')!%$
@r4685
CGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCAGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAG
+
D0F;!$=C0G&B>:%C%;>+;0HF-0G-0+4(;@/2AC?"EBHB:2,(+5<8ED%C9$1(9F*'+G*4'F6:/8CA3D;!&@9&$DE1("4CC-$*9#49(&B7#G.EF"8;@>(8B96?H$H'!(B&$35-D9
@r4686
TTCATTCAGTGTTTCNTGCCGGATATCCTGCATCAGTTCACCA
+
-&H(#+F!HCAB9F$%#C@&36#?.H/<A"BAF*.0F067@<7
@r4687
ATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGNCGTCCGGGCCGTGCTGACCAGCCGCTCA
+
%)39DH4D?#&-"$6D?4<963+@.>!BDB:G@0<!HC&3$#8!!9"A/,F-C+D<.%0$!),HF8(!!"&3H,%;D;2.B7&("(A@F-/B-))8F?(7D3GD?E.;C9GC'8E:DB
@r4688
GCCTCGTTCATTCACGTTTTTGAACCCGTGGNGGACGGGACAGACTCGCGGTGCAAATGTGTTTTACAGCGTGATGGAGCAGATGAAGATGCTCGACACGCTGCAGAACNCGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAGTG
+
,%"%(G6%5(-5(DD<&6;*B<C3<)$+47158;20G.".'%<8#)2'@$*(+89+.2D%CEH"0H3B-?"@,FE3!E8A!>@*-%A!5?+;=1D$+$&&>;1$2$7BCA.+8!5!)4&)'5>"6;=6,,).G&$22/!2:;*3(1HD3E2C#<,8'-/9B)*(
@r4689
TCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCC
+
BGH6!?8>B:EC@#H9'0<82!,6:7;/;!><8>,,#.-@:-'1?/>=";
@r4690
CTTGCCTGCAGNAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTG
+
A6//47E3(#%?(((@B>,03;3:E<>?*:!C=)F80>.;3,))@34%34EFC4#1/=*44,1@&.GG01?H/(5G1E"*29&&C"<B@/%1A+B#/"/9E8A/(&.4@9':.F
@r4691
CGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCAC
+
:9.'H2&8D.>9+AE!3."2:6C9H6;(A*(5FDB??=;2($DCD7%*9&
@r4692
ATGGTTCGTGCAAACAAACGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGNACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAG
+
&F>!8$/A=95(59+)7-@1?;=4+=C2(E/397E=::0%D6+'%#:7"<+222'9%C@(4E>;+D.3$A07.<C8"C1%%/)$HAB"?1F1&8+G0#0)DH:)7>%9(C="<E2D-5:*&D(3@%B$/F9;A-)&)*6>A)&5D?!=<>
@r4693
CCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATT
+
H4DD;+GA*-*<?C-:D58">DC%)$9F-.4H3'$GH,C"B.G<F6&#C)<F:-#
@r4694
GGCGNACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGT
+
)&(!&))!+*#!$#*#*&(#"#"%%#!**(!%*#*'$()++""#(+%#"&%("'
@r4695
CNTTAGTGAANCGCTTCATGGTGAGCGTGTTATCCCGGTG
+
&")+)"&*'+"&*)("""*'!%'+%%'')#%%!"*'!&""
@r4696
TCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCCTGGTGTGCTCCTTATTTATACTTAACGNAAAACGCCTCGAGTGAAGCGTTATTGGNATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCG
+
,H9&CH9HG#%!7B1"H8C!@4933F$#$GD4E#9)C.D-9+<6:'(EB':(/BAA+@1&(F!1%'25G4)!-+C.0.&()@8?%72C-EE)=@.9@'D6//!F2?)A<G)3A==>,6G03>1@<=F;("C/9:E=?@1#'F$*G('478$G83#),@C="5'#7"!&A-F/9+"&D0C%:6G0H:%
@r4697
TAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACNCCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGT
+
CD;0*4>9>9'??-B%:6H31=?(.8:;))1<0&</@H,:$/,A+:4%+/HHA4.10=1F?EH985-D)CE2?,14.A;7
@r4698
CGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCANTATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATNGCGGTTTTTTCTTGCGTGTAATTGCGGAGACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTT
+
<5#C+HA503)4!:&*$H;:7:<</"#H5+&=AB4?5$/;'%@363$*!C1;!F!>@*3CE4:!B13:?%"?:0$H'C':4D6&7H<9.=.G/"1=%C?G9A0(9/F6@*A'&%!:@,E>>*26A#1&A"-8A"$+"$3"608*&8;B4,.F"%?8'4;C1(*#&HF2;22B=C9A/$"52*65B*+<GC3@!*4'*@9
@r4699
TTGCCCTGCGCCACAAACNTCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATA
+
H)$',1?BHH;+;!*$#$$4@3A&5?7%F>C;3%=@GH7(5%9@0E?,G".F"!!'BB7:>""AC$8&#-33H)>8.'(&9'BD)(5AG-))@;/#9.&;3DF<%,$::"2"B,CH$+?E,'?%,4-?B"%
@r4700
TGCAGTGACNGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGT
+
0,-H!@1&H;+3';#"A0-,*$;;<(A>6)%=F+1"CG&;044F+/F4!D$F6<9H,!3."F&%G%1'@0;.<9'%G%26CB-AA46C2E)F(&@%-D4+?/00B91*D>8AB4:"80&'14-=
@r4701
CGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGNCTCCGGCGGTAAAGAATGATCCGGCAATGGC
+
825"C,)(#G-)"'2B@B><C*55D?:3)4(4EBCC6%-7/)"($:F?F<566A@*C%3B/("8;F7
@r4702
CCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCNACCATTTCTGCCATCACCCGNGCAGTTTGTNGCATGGT
+
B!<97<'*9&/"=;CC07#E=4(9(.G4=0C,8;E##!6A-?61'-0B+@.=F?&H,07:2&3A"%@$=7)%%+D8@A2'9+BH%BG8'&F7;)"BC;:E52(D&)/*6;E$#EE#1?A935'.6
@r4703
ACTTAGTCCGGCGAAGTCGAGANGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCAT
+
3G6@@7?);?H=C&D$DB>!G<5"'B&A'*9)'@-:FC1+.<89%!;6):,B9831G;<51?.-@C()4$9F7"<9,?-2)#(8A+883=!F(E2
@r4704
NNAACTGATCGNTGNTGNNANCCTGACGGGGACGAAAGAAGAAATGGCGCTCCGTGTGGCAGTGCTGAAAGAGGAGCTTGATGACA
+
#')("''!#"&!'*!#(#()!+$)&+'&!""##$$"'($(%#'$$'*+'+#$"(('*)$*"!)+((%$$*+#"(*#)!+""*'"#$
@r4705
GNCNGTTTCACATCGATGATTTCACTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCCGATATTAAACGGG
+
"(("&++"$&"+(#%!$+"#$)%+%&&'()&!&""&'!")(!&""(%!$+*')'$%!&%"#(+'%!+(%!#)")%!$$((+!*!!#*(&!&#&'&*#')#&'$%&'$%
@r4706
CTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGAACAGTTCCTGTGGGTCGACAGAATCCATG
+
H30+H=H>"H9/#B.3:.:G<CA?!'2DFD=6)E0.,64;/2E(B8$('?23A)-F)@6<;0)=F*+2D>?:40D8("3<)8%C70@7%,->)3G9";F;7(B)='*/3"B*)D4%G5.G:AC>$?BBA7'F93
@r4707
TAAGNTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGACACCGCTATTAC
+
1#13#2F)"&8:@3!=+G"/B(+$=2>($:?;F#'7%6G8:5%/.$.1#F+?6/2"*+/?,@$9C/71DH@A3G2"D2@D%D&B4>C%*C@(-6H.*8/99>%*36/F4
@r4708
GAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGA
+
*'BD%(#+:%%7#FE/?<==F?$>8)0'=36GB975E<12?158
@r4709
CAACAAGTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTANACTGCAGCCTCGGTATCNAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCNGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCA
+
%994'$*23$=D#<?1)EA!E:F=>"?,A.?6:BG6?!*BE;@:@"H;*C.1"/-7."49D1E<99G0=H&/@+"%@!=12(%#%2C+#?-(EDFA6G*-A'5B<7G4!?)528/(.D)4:=2*H?D/)-2"8992-;DF&FG6+<%4'815-'?8!-D747A$5%*!,6&"*;9B2C()44H#)EC<,2<=>(,?>D@.$:$@BF;;!>!E?";'3;D@5#
@r4710
ACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCC
+
$:4@1(#:=GH1<001!1.!&-1"*B!@?>25'>0315?@3,=,>B4+6.G
@r4711
GTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATG
+
H7ED94$7),#<1H0H&9D4,CH5B+.?C!$.43:;;:C)=A0B3+4H:F<)2(GF-&&?'3E'A6E4=(;A$7B+-9<C.'B&,G298=3*!+%G
@r4712
GGCNGCGAAAGANCCTGCAATGACCCCGCTGATGCTGGACACCTCCA
+
'#%"((&&')$(*')&&+$!%+++!"$%%)$"&)()&#*!+%(''&)
@r4713
GTTNGTTGTTCTGTTTAACAAGTTCTCTGGCAANCATTGCCGGCGTTCGTATTGCCAATTTATCGACANATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATGCCGATTGCAGCTTGNATCCATTGCATCGCTTGAATTGTCCACTCCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTC
+
$<;6-D&EH?B,>6(-5CCG+1)A5"51*:>:1G&F)F!H511(%39'/'#=#(8=@%97G?DH'5@/.F>4&*%29H&@75%A!A7+>B<B,A.%"A3!-+4E@<3=;H#-D7G>"?-=7#15A#+*//"F>%9$G143)F"#DFD@1=G%1A<@BD1=%4D>"=+1-208;'"F,3%3A-A619&>50%AE9D(E*$@+)")74D,F+9#1D2
@r4714
GTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGNCAGCAAATACCGAAATATTTG
+
47#<C6=D&:85&,0$A3-8<-94&3>&D!=!>&44!5-89><>B?F$H"+7E)--38>%H*,=86D3(@.?)6=.AE5(!;,;E>&(<,
@r4715
TTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTAAATGAC
+
B-DA*#>@'H-9%B6=)7D?HFC::<*-,A%1,/>->9'>C.G8C(G:AH
@r4716
CATTAGCGCAAGGTGATTNTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCANTCCAGAGAAGCACAAAGCCTCGCAATNCAGTGC
+
:A4/'!1.&$F$462,$6+(*#0>G(=FG2F;/(%)H)/!E,;2>G:9'CG,6-!+3)$2,5E&51E?:B:6;;9E/-*07&@%**1($1%,'(
@r4717
GCTGAAGAGATGGCATNTTGCTNCGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATA
+
1BB3EH89A80@6.*)2%.622=,H,?-&!H',HG1)6#E?6@9+1+,AG!>,!<>'B8+B$B@B8F-<"&%">G!7G,:?#!.1>+5H@0G,EC"8&BCA$2H2*-9:@0CAC?*<4=6@+DC@+56*G9+D.@
@r4718
ATCAGGGTAACTCATAGAAATGGTGCTGTTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCAT
+
$:0'A+>2>@C3%<'DE8F?*(#>GE2.C8%5%#H+<//,3>9:B=,+E14!6)*7C,.6H@1&!'&(@859C<C-&3H6(;8'+:#A:)@F3"3=;#;=4+83AD
@r4719
NCGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCAT
+
"<,E*.%#)$/)(3'2DB&?9B:2/)B:,:'>*65./3C39>BD"''/4)#6;E1>@59=,EH-
@r4720
CAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACACCCGCTCAGGCATTTGCTGCATTTATCCTNCGTGATATCGGACGTTGGCTGGTC
+
&(+&('!&#"'""+!$*"("$$'+&&''"(!&#*%!"'!+!("#+"+%!+#'%)'$!%!&!+!&%"%')#*!"$+(#)+()"'&"*%$%$&%"!$)*$&$"%"#"&+)'!(*)#+)$!)&'+#$%'%**"#&)%+##+$+(!'$+!#$!)
@r4721
TCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATG
+
4>49,D6G:3>F?$=F')='%=24&A1$6EC68=&*/D5$-65&B>?<>$0,:174&!?;/8@B/>*;E+>%15C3@A,F'?>.FE$&
@r4722
CAGNTATCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTNGCATTCAGCCAGGCAGGCGCTCGCTGAGAATAG
+
(%&&!#+%+*%(*+))%(%$%(%(%$%(+%%%!')+"!$"'")&!+*$$!'(+("(*(*()(**+#"&$'%)'(&%%*")+"'+#!)#$*)#%*+$('&*('#*(!%#!((!(&
@r4723
GCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCAT
+
-"1$'.2"8=9E1(-8+)H5A1BF>H;98BE@-(/>'65)*/@*-E+H@:5(<4$0)3%??)C6<C&1""#=;.C@7#;A'?++/*:=#2'G.<.;8/!$D1F6:==D4C!;<D4(;$4@61,7=&/4201,$
@r4724
TNNGTATTTANNNNCNANNNNNTTNAGGCNATNNTNANNCNNANNNNGGTANTGGGACCANGNNNTGTNNGNGANCGANCCTNANTNCNNNACNNAANNNGN
+
"$!""#$$!"#!#"#"$#"!$$##"#""$$"#"#!#"!!#$!!#!#!""$!!$#$###!"!##!#""###$"$##""$""#""!#""$""!"$!!"##"$$$
@r4725
CGCANCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAA
+
H@0AC!CG549($(,*.9,E3(!/&E">;$DFE432'*35G?F;-C21
@r4726
GCNGTANNNTCAACTAACTCTTCTGNCGAAGTGATATTTTTAGGCTTATCTCCCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTAACATGCTAAATGACAA
+
%&!'#%"#'&+*"&$%$)&!%!'(*(!+'!$"$!+!!+!"$%)&)!(#""!""&#&)'+*$!*#&)"'*!*!)&"(&###&'#+(#+$)%*&(&%!(#$**!##!+$!)'%'")'!#(%'*
@r4727
TGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCAAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGNTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTAAGACGTAACA
+
*/.G/H1E9*6(>@2'+)1,?%-+"(7ABH8AD3A*":5#4HG-G00C"-6">%@25*DF$3;@;!*2-G"(3B09%(/9")6#5"=0:4C!52H0,$GA+#@,81-3()H&+?'=#G/+29%@'6D43"4+/:<21#E+GC%)4H.@48/)5-47&4>,%;+691-<<F7)?*.C#,06B1EE*3$"#2H3"E!##2%*?:62D?HA==F"5:=4D3%?"A=H>>?H-
@r4728
CCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCAGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGNTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCANCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATAGCAACGATATAGTCTATTAATGCATATA
+
:::CE38!"G1H6!0:0$..*!-&A)2$:$#%3=8""13>'.5!&<8A523*2&".-F%55B1".>%$'%=2*1)7'<&DC2)4;B8,5#BH3+$7FD;&C*$%.;5:2=D81!4GD,8=3=2963/?!1A1+48'+:=5'5H'7'7,=&;*9A@+*$+G59'$*H:D5H+F5B-E.'*B1123==?3<=3<=$,)=>>;9<B&>&)"8'A0C@0C,)!50B+2&@35!"#6.'!H1"=,8:9,/&D4#G8"4"<2,*1A;)9"HD<%,-
@r4729
GCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCNTACGCTGTGTGG
+
827;,3!+&A+4CG1=93A!F,+);%#@#)0&(@1"<0+@!3>;<79,##?&.1"115BF
@r4730
ATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCNGCTACAGCCAATTTCAGCGCCCTGAA
+
F#(?6G")/HD7@?*)??G=>):0FB2.0)2:!<8+#0-GG/'D,(*.*EA*,9+*#-(?"77'.F%)?.A
@r4731
NCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAACAAAGCTGCCTGATAGTGG
+
%FGH;$+7,#,!60:>5F56./CF9->.%);10+0(,BD>))!+H624A10%(5.BC5("1C'!!>.,("&96A8,&+6H
@r4732
CAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTNTGAAANGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCNTTCTCTGTTTTTGTCCGTGGAATGAACAATCGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGCTGCGAGTATCCG
+
GA%CG5.)45>11!B%&FED97?4/&-67B=7*@F.3.B5/=70-!A;B4":,,,@?;=;%E6>/%"41.#@)F8B&G.1,G!-52"-&-GD%G/C16%@-;=122#1!A?8B,@!600/-+$?H99"A3(2CC'@"A>AA(H@%69E5/93E/4G%"+&,"!?>3.:>4(:-*%*<?D(1F8;<;E5$-)(4=%6AC,:*.1#C7,91,B=<5G853,&75&9A1F.1GA=/,(C.5#5*FG'%-9&$6-!<D'+A#A:F&/8.1C,39"5EE#&43?D9$A>'D@+B;HE3*#$H:;H-#EAH1A;
@r4733
GCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTT
+
F#E?9A8#$4F(:,@;7-*'B'BA=5;2+%)(4%G+AB36D<+E2,$B"=F@*;7,44@7=3"0:>>*G;)#:*E</F5>'1813,)<BC9?F<*96!&A,8,F360"9$CG'?;,<1'H+-7C99-/&%F>G<(G#%)*4-0#7#HG-?%F>?H
@r4734
CTGNAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAG
+
)"*'+%+#$#!+#%!#!*"&'')"(%**&+'%!"&&((#!+()+*&)'+#('%)+%!!+#'#$+#%*%%"#%!"#!)(%'#)&!
@r4735
GTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAG
+
G:000.,E*==#9#,ECA&(#$G:*1"!E5;D!.6C**+9+>@C'6$<*+(4:@%F4'=",B(6B-A2!"@9)9;)7H$C<<
@r4736
AAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCATTGAGCACGGTNTGACGGACTGTTACACACTGTTC
+
<-C%E7FH,&&E";=$H#$*2E*F)6)%H-*:DGH/+.F06A83;#!)?A>:H,61%DH/';,9.=52/4"1
@r4737
TATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACNCACGCGCTTCCAGCGGCAGTATAAATGNCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTNTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATTCTGTAATAAGCNGNGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATG
+
-,6G359G@$6D@,GG=",6/.,<>0&":+>>*;>D+D??81(+=,FD<AE#.,A1;9%F1)#;6H4H=,2.1C!2"(*&DC7%)#;D=$+57=8*++<;;:(6E8('1=$*,B);',B.F"A'"<37)2&>H'51&G%.%@-DBFB(C)"*H306".$%H;<C#>4)97806.-<"<5'2>2HHB?C6B:&GHD>+,*;(D"G!F9!:G'D<CC-@?;E1.>4F<7G";,DB:)G(09-,+AF+=/:.*<66#6"EB#!,=5B:>-*D*G./-#%("?$)&1&)73,+>!4)A&8*;,+6.&>B@.B+5)41).,F.<A".,6-/*=@E8:$G:A+-1%A*:%0&09,+,;!=$
@r4738
TTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGT
+
B!@3E=(!*A3'83,)<.&=:9A+F)##C#%2"7,C/(?%#1,467%<E0HE+1!5B3A'*30E/
@r4739
GTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAAATCGGTTTTCTGGCTGATGGTGCNATAGTCTTCACCATGTCAAACATCCACTCCGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTNAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGG
+
5<,*8<<4H417'D;(B9&:),?B;694,A32&)0?F5:;+7685%HAB2&?8,A67981E?*#"'&8HB<,1:78F8@.%)418A='21:CH+)CC1:C16"!0F3#42C)9/**F4!80/%136D>/+<$-//;F."=A5F)+6A.31F*.5,<<$9&@,+6:9.<51D)6F2>'#;F##4/%D;)"31G>#.=B=07;+G92!&E,D3%.'8:2/F>8#:3$=;F9+9*63F86-*%3'4":6";!1#)##CH)2:",!;8#C+-#&>+'2-8;@;%?3(*8
@r4740
ANNTNTTCAACAAAACACAAGGAGGTCAGACCNGATTGAAACGATAAAAACGATAATGCAAACTACGCGCC
+
(*%$#%#(()"+$"#%&&&*+(+"''$&'#%("!('%'##('%#$&$'%'#$%#'((&()+*$$(')!&)"
@r4741
GCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCA
+
H*H9-C0!$=";!:A3,("=&&2/26-?"@@7$,$/;GC+AD1/8649<2#2*G86&(((>'>.C91
@r4742
ATNGACNNNGGTNCCATNNGGTNNCNNNANNNGNAGCNGCNGACCTNNTNCCCANNCTCGNNGNNGNTNNNCNNNNNGCNNGGACTNNNNNNNCNAGAGGGGNNNT
+
"$"$"$!!"#"!"#!"!"#$##$!$!!"!!""!!$$""$$!#$"##!"####!"!!$#$!"!###"##""#!$#$#!$!!!!##"$"""!$$!$!$$!$!$#""##
@r4743
GTCGCGGCGAAATATCTGGNAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTG
+
;/H1?07@*4!86;<B/5:**69BG49AH1@*($H/G,1+%%(;*<9B)80A,A17G),$C8/:4D)"C1&>:+=,
@r4744
CGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAA
+
A6*3-$80!B!1,!&C82HF+8'7?16A:8,<6@502!G*BG<&7*7$<BG$=5A6'=B8<!;$2-2FC-
@r4745
GGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTC
+
=2</?1&CA=0G(AH7/-=AD7#'A%97A;/D:>4G3D-$$A*$1/@403/33-F;*'@D'.')52A.)02B<6@:D"(3:)H;'49F&H%2<C94+"$H:7A%)1D
@r4746
ANANNCCNGNNGGGAANNTCANAANGNGNATNNNANNNATCGNNNANCNNNCNCGTCTCGT
+
$#$!"#"$$""#!!$!!!$!$!$#!$!!##""$$#""""##"#""#!$#!""$!!#"###"
@r4747
GCACTGACCACCATGAAGGTGACGCTCTTAAAAAATAAGCCCTGAAGAAGG
+
+<6%:?7>;E8G$+'5;(:=<A?CA>/1>>?"';-'/'4,-=,G4/#D3C?
@r4748
CCTTTCCGGTACTGATCTGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTG
+
$F-=20!".)C07AH::2&)<7"F2B@34E8F?>'/9>F7%)5?G>="#3E<2009)-"B&F4C"'69E:=4B4"
@r4749
GTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGAT
+
&F8-!%7!&GGA,!#(:%;=>>!.)=4/F@0:2<<C2$/$:>#HCBE*-46-/?*;B,7AF-;B82,<2A)@D
@r4750
CCAGCGTCTCATCTTTATGCGCCANCAGGGATTTCTCCTGTGCA
+
E7)11H$H7(8!03/+??#=1E91@$D&5%D*#*F@$A*:A>?C
@r4751
TGAACGCTACACNAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCNC
+
&*&('%')&(*($(+&(#$()!($(&+)+**#***$!"$$"*)+)$%++!)&&%!)*$"$+)$)%%('#&))))+("'("()*)#%&#'!""#*++*&"!%&&"")!)+!*%'!))*'(!%+)%"#&#()%*(+#*!$&'((&!"%"+!#'
@r4752
CCNNCCACGCCGCNTCTTGTCGTTTATGACCCGACGGTAC
+
'$%)++#!#&+%#$*+"#)&'$%)&')#""%+')(!+%*)
@r4753
CCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTT
+
9+42#1@,CGB$#%?'':<(0@76#539#C!1%%#6@7+:<0(5+!$/$8F-5;)/-9H"2*%/504'=1B"$2)DG/-3B*';-CG1,-&*18<''*B7?"!@:-)6B#&!A!<)B+*@9&A5F/E9<F@(D=3<3891>%E?.C%E'@6;&GD<6*51+*=H"H7/;E%-#%?-D*A!0><$8@5<G?">$!(9-F$$/3$:6EH,)(-;"%(@'AB!#=:1(GFE;G9&"#
@r4754
GNNAANTNGGCAGTANNNTNGTCCNGCGTAAGGTTTANGCCCGTTTTCTGGATGCGGNGAACTTCGTCAACGGAAACAGTTACGCC
+
$##$!!"%*#)!*!&'')*"*+"$)#'"!)*'+"#""!'"$"($)#)'"%"+"%(!("+*%#"$+&''('(''""!*'$)*($()(
@r4755
CGCCAGTTGAGTGAAGCGGTATGTGGTTTCCGTCGTCNGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGGTNCGGTCAGACGGAGCAGGAAACTCACGCCCTTCACC
+
+.4-HG5235>!24AH%<.D435=B2!-4(!"&D:+,0*&0)$=5D6.!)***"?(<19B$4(24H:%.5:%$6+D58GB%&GD(H4G(/<*E,.<,FE:>G0AFH*"@39;BH>
@r4756
NGCGCCAGCGACTGTTCCGCTGCGTGAGNATCCGTGAGAACGACGACGGCACGTATGCCAACACCGCCGTGCAGCATNCGC
+
&?6>!*7HE-9)(;$=-+:5HB>"E#@:7D9>%7>#?%(B&1,<===A6+%C"3AF<@4((G'2:1BG"599!.@7/49$<
@r4757
CGGTGAAGGTAGAAGCCAAGNTACCTGTATTTGGCGATATATTAAAGGCCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCATTAAGCCAAAA
+
<.3=?'A1+>1%'&,7,/G///D1C49F+!@)$E)BD(+>.B+,9H"2$6*%+*#B2%26!#99%.FC@44':.6*#77@$/<+@F0FC8-B;%5DD/B%!7""D/7C'$7#*
@r4758
TAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGG
+
B.*7H"#:EH46@&=!=<C*,!7F:6(#-5B7*;(%$"2-3$/)B'74F?A=>B@8&-$B%%H94E##""5(/+2@6=
@r4759
CTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGNATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCA
+
=G,,02E,:;;@:4'EH:8(A$/15);B%5)H14#>B/CB.G"3?;'(6CC,:&"@%%2.;!-#"866H'$6$.88:5A<$!G83GF.G<10!*4!#
@r4760
CCTTAGTAATAGTTACGNTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAANCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAACTCTGATTACT
+
$!+)+&&(*'*(%#%+$$$")!('$#'#')($!'#)$!!)"#)'%!$#+!(#+*"(+%+)'%+')!$'"*)'&&)*#+"+#(!'%+%!+$)%)$)+#$#!!#&*$%&'))*#%#'+)+%"!*+$#
@r4761
TGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGTGATACCAGTTCGTCGCGGCTCTTCCGGACACAGTTCCNGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCNTGCCGG
+
#*+%%+'%%!$*''"+++"%*(#!##&*"!!+$"**"$"*&!#$&&*"'%!!"!%#)*#&(++&!+"%+(+)$(#%'$)#)('"+#$*#+$)##("#+*+(%&(##)"'*+*'%'#*!%(&&*&'!'!)!!##!)#'%&'*'%!''(*!*!"#!((
@r4762
GNAATNNCCTGGCTCAACAGCCTGCTCAGGGTNAACGAGAATTAACAT
+
&!$*'%$)$+'+'#$")"+&$&!"""(+)"*$$(%#'(*$(*#!%&%*
@r4763
TTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCT
+
-*;)*1&.(&12?$=4D8)G'/86>G/;39=E<BF"#'1?!&'E3??02?@BE,>F(C.4C/770*&!"79&>*=8
@r4764
TTTTTCAACGCTAACTTTGAGAATTTTTACAAGCAATGCGGCG
+
:AFA6A$"*A6'!;024+9%@.7;32(2."3=E#8F=G7*+.0
@r4765
GTTGATTTCGAGTTTGGTCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTNACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCNCACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGC
+
<G-2-7C.!3'FED.(:8.G>;*=*(+!6$+B(77DH/<FC9'@*9%.8:0*:++5C:C!,(H?7:(-+"45-EB9#.BG71(6H12#E-DE8B,HDA38/218H.D9F9>5!1?+7.F1D,HD>7?<B.8=(?$8CA#=
@r4766
CATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAG
+
=A(=)C:9(&;E('D?@'1,H#34>,3'AD>+H3--8"@H?3/7$!HH35B.,%!:7(1*-+/>G;:
@r4767
CCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTGATTTNTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACC
+
H*C=;99+G<4?-%1&7*6F1H#C?72'H&)=,,+511,%$2>07G(62G:"-.4@H*%G"G809<>$..B"H@99C-1B=1*H';@0&D'41C,)11?1.)2G/510H;#/A8-',
@r4768
CGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTCTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAA
+
88)!(9/BCE14E:$28.F)#2@=.E;B0%@C*/(/EEG-H7,=AF3G"&!34/G.:."F/.%D:>3&7D>:+@B;*#D@F(>DBD<9D6>E1#3930#,4+<E<9#G+!+E9BC$;62-E=<));?-42(0=<+4;)3;*A>91&.89C99+<=:,28A2(HE%1':-94=56<=(&,*5$E&+$#)).8$F##F$F!-%0:,;%4:"6;!4>G;DB3:-A$5;)(.<:6D7)E2+,+)<+2!45:EF>GH2-<2/H1
@r4769
NGNTNNTTCTGCAAAANANTCCNGAAGGGAGTAATGAAATTATTTCTAACATTTATCTGCATCNNACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAG
+
))"%!#*'&()***))"(!%#!#)*)"$+&"+!**!#"&#"!&%')%)%"&*#'*"&&*&#!!*"'!($"$#)!+'%#%#)%#"('%"+&(&)"$(*#&$*&#)(+&*++)%"!)$&+!
@r4770
TTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCC
+
(C45/6%$;-4F,?4<C:&A@CD1;FG8=&D/;;?A?'@8.07.A+8E#*90'>,;D5'A"$9*+D',.@A.0!-%#;@F:&%+@B%8%2%81>3.6%?:'%9550-9B2?BH:+F<=%=0F'9?B29,=7
@r4771
GTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTT
+
)>C2;#F>";<39H</F.8?1>C/@();/$'1%&F%2HC.)-"-6
@r4772
TCACCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCNATCAGCATCACCGCTTCCTGAACTTNTTTCAGACCATCGATGGNCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTG
+
5,=90%;8DC7=E4EE&"&0#0E"C?"CH$+D5""4;'5?-(3.F*?;306#>0=<5/*F.2-@D"1D2,%9+/F;;9E>F/H%.C4F@.9*%4&31$7-&GA8B?;D6E)G&/4',:4<2!@$D?*#!74@@/,;4B!2#BFH<3;"*.6#%15G/,59?=;G65
@r4773
ACCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGCTGGCGGA
+
#-<3B$=>EEA'H#+=#1G(B>11=;B-8>!!;9?8-"G/!0#&03<6-3)9
@r4774
AGGCACTCCATACGTCGGCGGCGCGTTNTGCACTGNCNGATTAAAACNCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACG
+
#2+,2-=4C09)D)"/6.+D-';2'1HB?C,&"@!=+76;<HD!EE>=".28:.:D7,H-'@#)@&,1:$8D;E6F4@H#91EG/G?,046:(33)=5&H#2(
@r4775
NTATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCCGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGNAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTG
+
"'G81.C9)#<79?0!G1;0!;=(3;DE@*!!D/$(FC%4F90=>4+-G@#'07/89.,/09H9B7*DF",>!/-90/B75%%B4%$$7B;?;+0-C'#.>G9H:7B9CCH$7G*D>,F#C,(G1::2>3,*@F9H$78<58F#:050A9C0,1>".?%@CH>.E67AG8??+G5=0!2C;(=7=+,:A6F9!&.&,-H43)H4@.@3!A<7+F++1$-@86)082++*#3+.%%"C1$/C.5,?2GF%6',D,#
@r4776
GTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATTTTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCNCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGC
+
(9E=364B"1H?35+=1?!&0.E7)"=H")!4-H=#+!FG'6))42@E"$79>(A,,2"!5+3778<2;G<A+8F=.BH,/E;-<2<>A00&43FH'3B>9)*!'2+%+=(881;7D0,88EA?@@#3+C4*!'GH)&;-;=8@3:&6&)89E1HEF0&
@r4777
TGACAGAGGTCGGTGGAGAACGTTATTNTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGC
+
)29=.-9;4!E@GG($/0;)A1+!';/C%2DFAC50G"F'&6>&2#EB9%&"E'5/4"7E1A<232-C>4#B$*824$E?AEF%F=$*G7&9*$0-E8.,>575'5-%?)$)>3D"B<-0-BA)#B+$F!E62B34**0>-/7-
@r4778
NAANANNATGGCNNGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATC
+
!)*('#&)&**"!+!!#'!%+(*'%""$+#"+'%&**&'$&#%((&&$$**)'&+*&()!#$
@r4779
GGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGC
+
G/;?!1;/.,/$0E;#9%F3&'&%:%!B8;A.8>&5G$B>(.+,;'%1E1A>%477)07E(#,>/)>B$0-#GF3<$A"26/5&/07)5DA9@,)CCH7&HE%2FB1AF6GH&D:*A#:=83F"2!-&A;C4&F'%:'8B#3)32'?%4G7<3.--+;*,%1;2=B/8';
@r4780
AGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGNCGCGAAAGGACAACC
+
D*A*.%7C9&7(FB97$,@4>@8>/F.D;"G=$C?=@<)+'1?:0&;:(H6
@r4781
CNACATTCTGNNNCACTTCACGCCACGCGGGATGAACCTGTGGNATTTGTGNTGCCGGGAACGGCGTTTCGTGTCTC
+
#"##')"'&"($((+!!(+!$%%$#*"%&(!)$$$!'!!*"+*#%(%"##$(+*('%"#)%!"!&$*"%)#'"#+%&
@r4782
NTCGTNAANGNTGCTGGCGTGCGTTCCACTCCNGAAGTGTCAAGTACATCGCAAAGTCTCCGCAACTACACGCAAGAAAAAACCGCCATCAGGCGGCT
+
"*&%&)"(%)$!"+)+!''&**#$'&&%+*"&)#))%&*(+*((#&%$&*!)*+!(+"#('+'")(*#+&&&!+(('"!"#!*$)$"+%'+%'$$$'&
@r4783
GCCAGATNTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTA
+
C:EG@(8@.>BGE,4#3,DG&.8A(:>&07/),$?D@3C286D+'((*'G2B:A;&
@r4784
NTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTNGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCAC
+
(+%#&%$++%)($*+$!")*!'$$#*(")$!+)*$")!+$"$$%!"%&"*!&'#*'(+&!)'((%('!*+#%!*!+'#*)&&+#(%)
@r4785
GGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAAT
+
E=<&'2DC@39#53+>*#B/=ED?+.4F6980=:A63GA"#AG!51,A+DD,>(/<#%,8E<FH057>:
@r4786
NNGCTGTTTTGGTTCATCAGTGCCNAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAG
+
"#*+!")%!"!'#!%#!)+&#!*$!#&(!++*&'"*%)(#)!+'*%$#)%)!)*&*&%"**(!"%&&*)"'"$%%"+*'"#(()()*
@r4787
ATCTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACC
+
2:+#/E1A(A.$,%,G("0F#+8C26?8E;B-?'-,8E84%)8*5$
@r4788
NTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTATCCATGAAATACATTTTTGANTATTATTTGAATCAATTCCAATTACCTGAAGTCATTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTNTTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTAGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTG
+
*&6:)?A--FE4F!<F%H-!%1#%5G/<&1)$&65$&64,2D3@55;63%F;&"H7F91"=8:##F$<!=$#66+B?&7%B:B"<BCDG!+82C:"E"/050%(:)@2F=%=(&C2!A624&!>%72FD>&+F*"=D#"4H,E<A?'#//9>7/,!6:=-0:+!?!A:8+(8-B,2H#6=!-.0,C;$=8!C;H26*>"%#5@+@G(A<=CFCH%,C7>C"&@,69&*!1G#DFE2%(;6>56E%!)/)H9%4-#C+@<%&3*=%8"<&->#'*3A6,16@:%C@!A-2<6!>?0<D,@A:!3:BG8HD5<1(-184%@;9HC/(3GD!G6D,G:B2H>3FFD&<@1&$)(
@r4789
TACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGT
+
;+#':,'*1:B<CGH985)#-B8%4:!&!E&G:"<#E.,7>>/,04:6G++..3D%"=='/>%0DB=%@2+1@*)?&1
@r4790
AATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGAC
+
8*!9$*8=,%/4=:F4D:+2F)#('!3%3:<,(-%6C;.B5*0D3
@r4791
ANCTGACAAACACAGACTGGATTTACGNGGTGGATCTATGAAAAA
+
&!9/6$4>G/%%6+":245$9,,2".$9BA&0-*C@8H<7!+E.(
@r4792
GAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTACTGCAN
+
0>?--<#9*A6;E)1?$1.<(3H@.9D+'G9B?E-3H'?+5>!A(G@$1BGF"D-$-?2(+
@r4793
TCGTTATCTGGGTAGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTCCTCATGTGTGGCATGTTT
+
/,+0-20C@D**8(%8.8%G:$&&.:H.*+?;1!;D*,@'G3@(>56/+>)BD4).(&4!@@BD-@"5:1?#*B%8G7!C<?=EG4)B"!FEC
@r4794
CGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCAC
+
C,;$D=8/F8+0)A*H$955C1*EH;.*20+>940BD//283=
@r4795
NCGNNTCCCAAAGAATGGATCATACACTTATGGCTATCCAGACTAAATTCACTATCGCCAATTTTATTGGCGATGAAAAGATGTTTCGTGNAGCCGTCGANGCTTATAAAAAATGG
+
(#$!!%)*)+&$($+**&##+'+*"!$$(!!"$+)('(%+!$'))$'"+)")(!+)#"+!"'($**+$"**"$'$$*#"$'*)'*"&"!""!)%*(*$)$)#')"#!#*"'**((*
@r4796
GCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTANGGAACTGGCGAGCCAT
+
,!83A!AG,8(/=H0;9<>2D!/;"-,3,>.;8:71$58(!8;:B='D28%G4G04C6.6EH?C**/A@249!/?*6EE)@;E9=:&>)1$)%$!29<B;%,"AC'0)22F,()9)0#+4DB31#'4D:5G2H151*'
@r4797
AGNGANACTGCACCTGGGCCATGTAAGCTGACTTTATGCCCTCGAAACCACCGAGCCGGA
+
%%)&%+%%'+)!*)'#&#&)))+(")!$!%+($)$#(#!(&(*)'$#($'&$"'+"&)!*
@r4798
CCGCATNTTGCCGTTTATGANCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGA
+
H%7E4()4;B835#H1F89*4%"G;?A-:(7#*9'@91HF2D;(36?@=A2D,.79G!A9+D'H8DGB,H#+E':
@r4799
CATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGNGCAGCCTGAGCACTGTCTTCCTGACGATCGCCCGCNGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGT
+
8F*A05'E$0!%*:#(A02::;A.#25H7"))A&4B+@+(;&4DFAC1..F!B16<"*3A=/%=8D6$(<$3/?<HB'E@9(A.:CH$$4<G@D9#<,+.6H5D)"0!/+6@+*-;3=F,GA'#1(#1F(03?-8!=*1"A;>609G!(@3:'=9)*6.3%-6$C3>/:+;*%)-D2';1#>/+'G/02=637%9
@r4800
CTTCCCGAACGGCAGGGTNGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGG
+
G2D:)@;@1?9;0;>/$@%*-/6HAD)79:&;C/BH:)#&#G$.,:DD:4'!+*CFH->
@r4801
AACGTACAGNCGGTNCAGNANCTNGGGNCAGATTGTCAAAGACTGGATGAAAACGAAAGCGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTGGGTG
+
'%'*%'')(*%#&#&'%#"'"$$$'*!#(+"!#$*)$*("'&&)"$*#'%%*')"!!&*!*%)("$")("($*"(!)'$))'"&#+"$$("+*&'&+(%##'($
@r4802
TCACNNTNANTTCANNNNGNNNAANANNNNNNNNTCGNNGAAACAANNGTTNGNTNNNGANCANNNCNAACCCNCNNGNCTNTATTNCANNNNTAATNNTCGCNTCTGNNGTACAAGGGNNTNCNNTACNCGNANTNGNNTNNGCGCTCCTGAANNNTNTACATCTTGCAACAATCCNNAATTCCAN
+
"!$###!##!#$$"!$!!#!#####$"$$$#$!!"!$"!"$!#$$$#!#"!!$""!$$!$$$$!"!$#"$"$"""""#$$#!#"##$""$$!!"###!"""#$"#$##$"$###""$#""!$!$##$#!#!#"!$"!!$!"$"$$"$!"$""#!##$##"###$"$###!$$"$"#!"!$"$#""$$
@r4803
ATTAACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTA
+
3<**!(,;DF:2GH%!BE?"5H%$,32:'3FB9'>C6?*?>%189$$98"1:D+:"4>0H;!-;/$6+/@+!!@2?$?;A+<+G&5=*>3#=8G"=$)8;#7;.
@r4804
ACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTNTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGT
+
FA'FA)DDE622.=FA&)&FG0;)G<>&;A1(#0#!7@0&,5,#!,GE)'/0-H,G7,(GA1:+?*;F<(+FH4)58(!>B9)2')30E1.'!)07">7@/EAG24+C2'9%3'@#E:@>20?)5F'$@@2CE=:;@@D%G04(F*A:3
@r4805
CAGATCTCGATGATGGTTACGCCACACTATCAAATATGCTG
+
:D$&2?05:3:"A)?!7(H95<!"B:0;18>H:G*104A*1
@r4806
TACCTGGGGACGCANAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTA
+
7!@2$1?!%D!&?+=F,*GA!';AC661&A23?D0<G.0/8//3B"=9/F9/;6=$+#99#/6
@r4807
GCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCANTGGCAAGCAACTG
+
8)(E%:(%6H/7FFE-6'1A#C7!>C6H!4/!#:)?=/)$G7D#(D/(38H1>0H4'
@r4808
CTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTANTGCGCTTTCTACGTTCGTGATTTC
+
)F+!E"@.%"G48E?65E+27?#H8'"4-1#*>DH3(&9B&,7@H/A?=35(%F-B<BH"-21>G='G/'D(EA-&'&/%C;$')6;*;$C8%-?6+A-GC6
@r4809
CTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGA
+
D)(/B%8CA##B9!<D.2)B/06B*(20AG&C6:E&,/#+5+3+&#CB(H
@r4810
CCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTNCACCGAAGGTA
+
8++<*0(E%%D@1D6*&84**.;"4B6#=="?HH$5=.0(+&C.&(&*>5A.+9,H40!
@r4811
AAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGG
+
93+@7C%4::=*"E-F.<5,C>)G#!G*E'@</6;=D$#348%3?C.E=<HB&,)*6;/D@&-1?%G)<!$H=,9&7+'(*,H-
@r4812
GTAGTNATACGGATAGTCCTGGTATTGTTCCATNACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGNTCGG
+
)()**#+%#%(&+%$'!+%&!#!&"$&((""!%$%)'(&*+)##*"""%!*!$%*''&#+'*"&)(%$!(#%!)!%&'$#))+$#)"!"'$('"*"%!))*!#($$+#+&!"#'*(!++(%+"()+!!+%*+*!+%'"!(#&'(+
@r4813
AGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGNATATCAGGAAGCACACCCGATGGATACGCG
+
.!52E.E0&@F>2*7,/G;E*/,3.F).&G<0-30'#"!:=*5('C<>>C=,.(8*+)1B7(F!4.9;(D9,$<B!7<+/%DB40+035(6(<(4%DA+'?:3094E!.*2)5$)@5FG>D@B0HD:C"G),<3+-?G0F26DA6C=:)+,,7#$334<20,C&$B$&.?E;?@C,5!/"&<E9(?)*65%?=+AD@#F1.G"H@*&6D6:G%'G$!(E7;@@.$D<))*$"
@r4814
TTGCGGAGACTTTGCGATNTACTTGACACTTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGG
+
=D7(#0+9A?)#$@=HDA9CHGA0/1<.-G&((=1/0A(!CC+HC4H'11;.870:E8F:*1F0>@9GFF3"(@>/90$>@+/2*;'!6.494-@.=*9H)"2$"/(0@D,;/6(:?@F.6E7-'&D,,
@r4815
CGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAG
+
A>3!@-8F,5;69("/B.15+)7%78.B?!'A1EE(G;<'+CFA13A25/0C,2-/8>*4/5(!;@>E3,(/$9>2*-<',=$*:4E7(B7
@r4816
ACTACGCGCNCTCGTATCACATGGAAGGTTTTACCAATTGCTCAGGTTGCCATTT
+
*+.,/5%%9;4C7G03G@F5.4<-@A7$%CDG92)1-&@F,H.9:.03>G)'.!:
@r4817
CACATCCGCCGCACCAAGCCGTTTTCCCATGCCGTAGCGCGGATGGGTCAGCA
+
0/*>H-/@B+E%4E6.DC'#(C36+9F&"./A4$B@:H14!@,E+5840?A/8
@r4818
NCGCGCNGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGA
+
#'-2<'D$3?:EG-=.0*B7C'B5-H6D>%E=0C!1708,<<?;"A1$#(+%72'B*#=:9/!7
@r4819
NCTTGAGGACTCTGCGGCAGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGNCGCTTCTGCGCCGGAGGACTCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTAGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTA
+
#":C-:**B#+2C3$84D?>0;C=&578/0+03%"8%H0'(8A3;#::,0>B,+.C082'6A'6>H<>&4?C3E?.%0(E1&'!G827G;03$A9-C,A=F$+%'.(FC&=28)-DF=C7#%&FF'GE85!3,-&BG$#9-920#G&<+8@31.'!9$7@6(4H'*H#?B4D6%44*E""4;DEB;/@=E&:=.0,>.#EFB79B:E%H**6:0"
@r4820
ATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTNTGCGGCTTGTTGGGCTTGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCTT
+
@3$GC?>"H4B;92BA"7'D@B@A*33$',+9DF3A54?1G9H0-.@A$0?@5=G&2!;A@B4?3H!$E"2D)(/E#76D$#'@C5:G<+DA7@50>2)H'B$(67*H*+8=?B>D<>27-G(2$&.47'65#4+,53E<"=$;1%E9/D!FB)6>2FE!?1G1#'$)&18/!8#)=9<#+A!0>-$BEF##5#!?B
@r4821
TGCGTGATGATGTTGNCGCTGGTCGTCGTCGGTTGCACANCAAAGCAGTCTGTCAGTNATTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCC
+
&07<!67#DA./@0'757</&G0>4%7+8D$G5-01<1H40G71$?B/>FF4""GEG715=5HB9/+@;48E'2!:48DE%&2;"5@E2973()$4$#,D;
@r4822
CGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAA
+
B7&,(</#E=%%D/#%A,'2<($<CB>?*H-D-&F;@<.BF##D?(H4B2*+97+42=&"-H<)5B!*6B2@9H+7
@r4823
ATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTC
+
++%%*$+*&!)'$&#(&'!+*&#***)*"&"#)''%'&*!*&((*"*'+(+(&!&$')**+(%%#+'""$!'"%%+&$$"*'%#"!$+%)!!&%'&$+$+%)%+%$(&#+'(&**)''$#**)"$''##+%++'%!++)%)!#!+)+&**$$##')"($+%+*)$"++(+*%$'+!+&"$!
@r4824
GCCGGTGCACATGCGCATACAGTTGGTATTGNTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAA
+
7=?%!3"!-B(>1"D+8'?C.B4E6/C,8CH.61)%BD%/A%@*#AA=A21*".*$%>()20FA1>1CA/(HH(',1=3B!F4(!,8EH.(F*F/!,!F1=<C.'-<%>5-*8
@r4825
GTGGCGTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTCGTAT
+
#$8*:F2@A69$+"#:6B+6/B%!BC%>#9A!#'DH:/!D&)7H4E%"/328!)83HC-D26;8:C?8A9)+7+?="@?:<0+2&#A,A4.7>15.718?#;B#.B&)!A8D20!6D?/.#/+B,!55E!646:?.H@#EC2
@r4826
TACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAACTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGC
+
B)-71(9<5@H;1>=)='$5)E!9AH(=!=7/@'450+=1+,2>'1B5582,,=H8@1</1)9!E/E08'/74?0D%+27**"4%C<B--@80.#!+!!>D41-+3>C:B-,C()B>@+/H
@r4827
TGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGA
+
8=*BD(;:"$/!C-.,%2;'5E-%E%E(%4?>48!:!-E$E*E#$D)&92*+"F1;)8A$F*--+8
@r4828
CGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGG
+
A(GA>8A></@)+0"/8C:5/,#'8'"8?%<;''2E/C"7A1E8%2!('+A@.6/3AC&!/CH?/,DCH$?!"%#&&+9$5B":2(F1%BG:F8B)691&=9"7
@r4829
TCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATGTTGCTCAGTTGCAGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCG
+
D?206G(!GB,E6H6>:53/C,?)/C'&2.,,<77C@418&D8GE#D$6.3D9E)01E=3B>>"3#5)#-!?-*FE79;%#()$B"$;AH3,!!D*0/%%*6+%@$A7
@r4830
GACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTNTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTNTGCATTATCGTTTTTATCGTTTC
+
@=)D+=FG.9+9%!69/!6!G*G-)&<202C@?=:6=4DHHB&75E3-/".#?6<$6A7?<;#-A#('%$C;E;.+>556<>!B)=/<G@04DFG4$='@9%HF>9%,4"=HD-)=F&E1?H!7:G-;+1D7*A:8!$H)F235*+D.F-/6)2""
@r4831
NNTTTGNGANANCTGGGGCNGAATCCANCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGA
+
"!#%$)!)"&&&($'(&'($()&##&)#++#('($)"$#!!$&($$!)"%**++)+)*")%&"*$#+&$%+$#%*"
@r4832
TTACAATATCGTCCNGTTCGGAGGGAAGTACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACG
+
4)/E<G:B9AE'D*!1/E/C"7')"36'90,!(!>BH;<+67-99B?'5HC:3.@*7<-A)G=!./:8H6=01H#(-39;<"9-778&G7FA)#H=2=@C
@r4833
AGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCA
+
8B05E,(<,<+$+?436&%(A4F<>(C2>D074;*G1&*,G<4"H5%>?0C$C'&0-8)79
@r4834
TCCCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCAT
+
FE=1;-55$.$*+.D1&9)9E4E,*+,9>:7*=C!7/"-<G1+#*)/@2'D*5F7
@r4835
CTCNNCNGNANNNGNAAAGTCGCAATCGNANNGNCNGGNAGAAANTNTNNTNGACCCANTTNNGNANNTTNTCTTAAANGANGTN
+
$#$!!#!#!"!""#$"$$!"$$!##!#"$$!!"#""###"$$$"##!"!!#"#$"!#"!###"$##$""$"#"$!$$$$"!#"$$
@r4836
TTTCGTTGCGGCCTAGTTCGCCGCCTTCAATGCCCCGGCTTCATCGCCGGAANGCTGCAACTNAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGNCATCGCCGTCAGCCCCGAC
+
1>*%71;"8.CF6/12')+#04'A'12/*E078!&0>=B$!(D3FC-H,/$>-A<<E*,%8H=.10F<8?268(*%(@?8">=3;$70F.(5)A1>0B('@47;*(#+1E@B"0"65B!<43:90??G5#
@r4837
AATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGCGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTT
+
(*,G.(7@891"!1%58A%0H2%!+?6F?B0-&!(#1?#D,6"2(D>:4F)A7.H?$#$5DA4#68:?H#D=!G=FC7HD/E:+8#'=40-;3+9/5)=>$()$5@(AD+-,:HA=FH&0(@8=1>2D='*A@."!)00
@r4838
AGCAGTTATGGTGATCAGTCATCCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTNATGTTCTATACATGCAATTACAACATCAGGGTAA
+
?#=C2A++/HC(+8H=85C,6A!(GD=@7D(&CAB)79HH!74)#"C95GH>03;&G;9$77@;A#,.28C&,/@@81>7;,/C04*"&@"CC179&<%&><7-4(2)"7G'<4/C/,:266+&,71#4>/,E!<7:@
@r4839
GGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCCGCGTGTTTGTGCATCCNTCTGGATTCTCCTGGCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCAATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGATTGCTNCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCAT
+
@,/E6<735*E$(A=-B/25+=."H:58H5'$(@)/</3%"$1>.D#3,=1(03@"+@>6"5&0;"/C4700'2(E,4%9D?02$(-1G<%>H1:2/DGGEC*G"9=%0'!2*/$<"<-:A2/6=G0HE&:$D)5"A-,$12+A/'A"F'@=?#4/)-@7@3>=@$&=A75,'C$=28F.0E5'B<0$&?%;&+*F@*H)H&(+C(4/FE)%::4%B;/5%$H8=72-)/,6$95#>/54/E$9@+"#84EC>=E95E,H99@C$%>42
@r4840
GCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAAAGTTATAAG
+
%%4FE8&5E1B=@?0%AH;=9#*/8=(/<=G,982!*H:%<2039#%!G-.
@r4841
GAACNGCCNNNNCGGGNTGCAGNTTTNGGNNNNCGGTGCGGCGCTGGGATATTACGTCANCGAGGACGGGTATCC
+
)""%!**)#!###"'"*!)$&$&$!"#""(#""*)+$***#$#")%+"&!"!$$%!**#%(&)&&$$)*"*%+$$
@r4842
CCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGATGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTA
+
&;;,A140-8<5@>1%63C!B5;"EB29.&38F6E9(C9/4-4'-=D&/&'21.G#FA=-8#4=!$;%55HG?GHD"+G(=&2(8:34'B#&:%F6$5C'1!%=62H?*B*/<*-!"2H6C3A$&/0*D"$<+/"4+0/FCA&5
@r4843
CTCGTCCATTTTTTCGATGAACTACGGCACGATCTCGTCAAAACTCGCCATGTACTTTT
+
$;D(0E>/$E'760ECCH#;/"-=)>E3E58-6;1FE5B>"55*+E?.*)1&BA,6;'?
@r4844
GTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTGTTACGG
+
0.F8*F6$#7@!1%@-=(H$'?$?*7=&$)*2$A!EA,;(<6&+
@r4845
GGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGNCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAA
+
1$4>.'<'6;95CD&0@&GGB&1B#2=B==58'*!!+;/.%=B6+E5)B(8#;6&D:2.3=).'&38@=4F+5H7DF2H?41;--:1,0;95$(1(;>..%G?-'?4
@r4846
AACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGA
+
!9#G2G?C&&DC7%&$%36G/!?<.FF;")!-D*8!>'&=<
@r4847
TNCTTTATAGAGCATAAGCANCGCAACACCCTTATCTGGNTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGNCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGNTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAANGTCCATCCGTGGCTTCACGCCAAAAGTGAGAGGCACCTGTCAGATTGAGCGTGCAGCCAGTGAA
+
&+%()#&""&++$!'&#''"$#+$)'$**%"'&&+$!))%*!"$(!+$(&%)&+'&)$#*##!!!##"!%*$%&*$*'#("'('+#$$#"!)&!"(#+%%)+'(%#&*'(&''+$!#&*%&#+%%(&")+&'"*&)#+*$#$)+#+)'&$)(*#%)#("(%++'&&($"!*"#%("!+++'$))(%!$%'!$*&"%&#""''!$*#(#!$&)%!*+!$&!!+"+$#!"&$)#)!"*!#$"+$'+#%#))$"#))&"#()#$'+#')#%#)''*$('#()(&!##*!&+&'#+)"%#%(*"'*'(!+%&&'%)$$(&$'+"#('%!!$('"*&(&(*!&%+++"&*%&&*"!**('*%&+'#!)#+%$%*!$!((*)(##&&!"(**+%!*"()'&*)(""#$!""'!&&)**(#
@r4848
CCGCAGGCGTCGTAAAAAGGGGTAGCNTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGT
+
1266,8C>("6EB7!+4&#B=-)B/9#7;61*.<4A%,2-@+3;>0!5'!)2D%6.+$>0H:E&5D<F)0:@6$"$8;B,"%C9?8><)=D:@-F/'9HGAGE.H4>2-##-9&;D2@-8=H<#G',<?<"B7B0
@r4849
CCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGG
+
71B'367*";).?&"%7%&?F/A50'5)8$$5"G7+@&<;)0&=B.*+?E87*5BD284=>'0#D)64B88HCE;H9%98>540<*=.87:C
@r4850
ATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATNTGGATATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATANATACAATGCCAATTATA
+
+<"5,F50=.0G#5!9*F19EEB&3,=-"==E('*?A+.G<9@:C*."!!6A5='B<"+H&<G@B*#$09=.D*$8?!>62BB-+7(CCCB.'$HH/67D#!*D3F,-:FCAD)!+?!,/$:4E975B5BE()9.G'(""F;-/D7B7+7GA4."-#E<7+=C@1#H!&>!:7&'+?8;BAH#%>"DF=-D-(#>G/?%G@1<3$-$3%;"%-=)-C,9DC==?
@r4851
TCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTC
+
%F&<+G40B<0C:>%GC?9/.9#"5$'@$C-D;;:>!"+/3A=;6,7'C(.39")D'7);(87<F:;F*#@A&
@r4852
ACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTNTCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTC
+
-3'33:F#.&DAH25?$;G"%H>&?)C'@<FC&#2.2F%-50.E:7FF)E:*?$H-A<=G1B/A*$B&/CD18%78,2@FC$##83<9.$)@%$48&:(/,-2ED"'*)$E*>/;@)@2E&!7"'@"D,-#&&>-BD,+.1,8%D5$E':F;.!#A0H$>(&EC%)5D;;$."%C"$.FGH8
@r4853
TNNTTGATCGATGGACGCAATGGTNTAGCAATAATTGCNACTCATTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGCAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGTGTTTTTACTTGAAGTGACAAATTCTGGATNCCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTA
+
!"$))&'(&+(%$)!(("&+&)%!+!%"!"'"*&+&+'!#'!%!"+#""%+$!%'("'$"")*'"#%%$%&*(!)%+!*$&!*!"$+)!!)%*#*&++""!(+#$")%)*(+&&*!%'*)'*+!'(%"&(*$$"''"%"#&&**%"$($+)#!&)"&*$+(#"$)%%*'*(#!'$))%##(*'+++"%"%"+*$+*)((*!!(&"!+*#'%(&*%$)#&!%+*$"*%&$!$)"*%"+&(&"")&*%%+!*'+#!++(%$$#"#'$#)'$"$+"&&'!("#&*)+'(*(()#''&*'&(&&%+&&!)
@r4854
CAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTT
+
0.$)C93!.0!7@<C.(88?*F7,7#;.G0$*/2AD@>:@*&$>$EF3E8"@B5,=&&BCC>
@r4855
GNCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGNAAATGTGTTTTACAGCGTGATGGAGCAGATGAANATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAG
+
("4(*1-7=@0C,1?!-.&;6+DF157+<DH5*C0H>52C8/4+3'85H8<3$A86+C+-D")1'1-1<$3>52F%F,FB7;%?1)E#+G-GG/4BF&?(&@:#.A>06A&1"!$95!62H'37"?(1C:!A)9=')3<,!3G@B#;(<'.D6&6'',E'68B!?5)2&F/=")&@H"391!,*%9-G(-*38%C3B40-:?E44=6433$$0@"&5#*F);&D4"=#,F)!7)FA@
@r4856
ATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGA
+
H5+'=E!+;)!0EG0605<2@2=H,??@37!*+<<6,"9/EC"%CCA=-B)&5661<7@$)H?5:<=1,288"$7?-E#*HG+B2,7)$:F@D&'=5:+H(C12*'311;!.+,4'BC.+<#"E9+!:HA2HH+HH@.8<@;CH9=;309=)HAH6*'&&4$&5#5HE#@3!/C,HAAE3F8+:6G;#2A:EA7>-@++2%.=%D".,5;9A@0!06E&7?E$*H"A*C2->/!)%9.G8>7,H*C8=6.90!GBB;>>$&A!'8!@!1/'+H0#GG*='H,-H)1%9*D8?3+&G"7<?HF*.8"!-0$H8##+C*&/818DGE#0<$-66:%+':,0G?8%!'#%EFG):;32>DC$
@r4857
CCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTACTTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAG
+
>)63*@3.(#/?7GC@8.@2<H1G>H07AG#F"37F$.<C"9@H#+7A,%.:H'=E2,C<C(#.;E%#?42)6(=#D"3/!"0>6=?332D%2GE07=5:(A%6ACA6-"6G4#40H#9G*!!@@:='!;*D1""B4&<A"@+&(,06!1
@r4858
GCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAA
+
=B33:;F4<=4)<-#,ACD"!/615CG(4/C7)G!E061&7/8%@;*+$E5@:>&:;--5;E/<%$$H<4DB0(6..>.9!3HH)GHG<B0E9-E=,3F(8*F1>/21A>0%*!8/F193E187
@r4859
AGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATC
+
;;"525%$$3*B?#>33AF1$4H=<$@,C;38B(G0A&@C!7$.1
@r4860
TCTCNCAGGAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGGAAATCACGCTGCTTTACAGCGNCAGCCATAANGTGG
+
&*'""%&(#+'''%(+"*'&"'$%+%"**++%%$'$(+"!!&+%(&*$&($)(("!#&*'&+&**$"+("(+"++"#!"
@r4861
GAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGT
+
-("*3@-E5B";=/D+2C@1;5H@E?/@B#)!>F?G4*@8&(1F46C!/G)74<$2(#'0+71>3?*.5$3D/5B$>'?;(
@r4862
AGCACCTTACCGNACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACA
+
+)#!(#")##')#*$!!*!)&"("!#$(*#''*$&+(+#!(#!&*&+(')&&#
@r4863
CATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGANAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAG
+
%-52"?+C$#)1?/;8,)"5!G54%'@)'B7EG)FHF+4E:'-G667,=B%H2H<&":.4F"4+#+/ACH89H='3'</:#,(FC>'3E'(1<$87+-'4),>/=#@B;C/0#E;7@=>:A<-:1E<<?+GF%5"H-%"138#?4!1.H8
@r4864
ATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCNGCGTATATCA
+
)679B7$2+3>$&&(.8=)!?'/'?E9BH+H(B,@!,)4-(6':7/E2)--$4H4!,9<8G83;3,(+G<6$=844<&$62!)";<1B#(.<2?1'C:60!=>)+7$')
@r4865
GATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCCGGTGAGATGAGGC
+
G*C+FFGG!9"6'=G4!&@-<$%C549)E6$;2%(5?/52<"<->'GF(C&1F0/&A..;7@$%5&,2"?DBE*
@r4866
ATCCGCAGANGACCCTNCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATCCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGNTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGAGATGGGCCGCAGTTAGGATTATAANATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGNGGTGAATNNCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAA
+
*&+!#($+)*$%%"&!'))*%)!$'&$)#'('&+))!+$!++**#'&(&+''**#(&$((##&$$!(+!)'"($$+#!)*")#*"%!&'!)!%$"#$&#!!%&'(*++*$&##%&##**&*+(!'!&#(!$$'&*'%#''&*$*!*$*'$"&**!#+"(#'"+($%$"#()'"%&())'"&*$+"+)$!+&'!$'!#'*$+$%*&'!%%$!)#"!("#$(&%*$(')&$#$"#&!++%$+*(!!(*#$%)""(*$$&)!)*)*(%"#))!&$((*!%$"&)%*$"*&+)%%*$+&*+$"%'+#&#*!'!#*!(+%''*#"$*$)!!###&#(*$%$*"*(*'($'!+'*$$$)"#$)&#++*'$"!#&(!*")##"!*(+"'#
@r4867
TAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACT
+
443+(8:)AF21::&#8+H/3B4==*F>4C*-.&/?E-"#9%:FEE,4+%$E3=>+01)8
@r4868
ACAGTACCGATATTGCACCGCCAGATNTTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGNAGACCATCGGGGTAAAACCGTCNATGACGTGGCNTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACNTGGTTATCGCCGGGAGGNGNATATCAGAAGTGGAACG
+
;<**&HF77#+?F<%*642.E?F=2E&!%CA1A%;A7!%+/#@1B7-D0A&4&/%4/EA$D5!=8%,*%C&E:-3+!>3=.;@!&1&<2F%;$!B'9;,/)5!/,A%39"&!/C80D?>*.9A3:9F##E/:<"@-$0@)>@<,9C$&)FFG(<+',E'6=B32D;E4--*6?H*>$.8F5'8$4(#$7?+8D?>'F<;4+#3#((88&C
@r4869
NCCNCANGNTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGATAAC
+
)*)&))%""&+"!'!$'""'!)+#**%'*'*))"'!)+)($'!'!"'$)''!((#$+%'")()%
@r4870
ATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGTCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCG
+
.3,CC4;8B!)>-73,D@E=(A$.9##3HE1*"BF>0<:249=64G*9C<,EE8<8+>&&7<6=:/2+=1,F1'91%G8;6!#;)H1-;'&;-7G&&>16?E.@..;C':-CH(B=!2)'08G?.,3-*9:8=7C1".?@55?'5A4!258G&!D:.FA45.,G
@r4871
AAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATNCAGGTAGC
+
).&!"($/!$#B:.A!><A9%#F?EE11D&()"<.7<!3D>B('.;!-</1>A'',6/
@r4872
ACCATTCAGGAACGCAACCGCAGCTNAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGTTTGAATGGCATGGTCGCTGGCTGGATGCAGAAANCTGGAAGTGTGTGTTTA
+
)*@8.#?&%D45F%E81&C4G2(6A+<922/?2&G#$F,HG8($?%:+/#8$&':011'HCE6'907A>A%.8$5&7E)<4.*!7;?EA9%6">"$GD>9B;/1))G6>H!FEG=@F'A974)&9&?
@r4873
GNNNCNGNAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGA
+
"%!'(!*+(*+%&)$'!(&%#)#"&)%(+)(#&!)+!%!%#*+()$*#$(++'&+#&+"()#
@r4874
GNNGNGCNNGAGNTAANNNCNGTATGGGCGCATGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCTAGTGCCGCCTCCCGGCGTCTGGTC
+
!""*%)%"!(%$)('*%')%!*+&&%&'**"&(&+!&"'#(%*((+*$'')*)#(('%*'')+&%"#%$!)!&*'"%!#*&!""#$%&#$%(#)$$
@r4875
GTACCTTTTGCTNGGTCAGGTTGTTCTTNAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAAAATCCCTTTGNGATTCTTCACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTNAGCGTCACCTCA
+
D:H;.EC/'!,5<<<G'*(H4CHH7?9&5!/:5G"7%:.B814&D*;$/65%A!0,@62?A;A&EE7)C#=H+;4.>(F)H9-A0C14<.,()39"(52;36(3C!*%B.:3CB%*B2%54%>(@*=!4?:=$;!;G.1?80?$54<2@05>*HC".$%%A'&&AC#G#@'0B"D,E!?EAC'*)9128@82&#=@;G&*+D%0D=!)*B5D%GA.3E=2+B87@?,002B;*&!E=H:9=H7#$"G&@G)<%1G=EE.!:
@r4876
AGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCAC
+
3A)B?<?4G0$%++E.F,E4+$:B.A4,D4!<B9'($#!%E!)&)0+9H
@r4877
NANTNTCNTTGTCGATATAGGGATGCANCGCTTGGTGTACCTCATCTACTGCGAA
+
'"((+!&$(%'%)$(&'!+(*"'+#+)!$"!#'('"+$))"($!"&&(+%%%#*$
@r4878
CGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCG
+
.&*!F!;?8)1%(!:;-6<7%-@0?B@2)'.D9BBH9!*;86HBA<0#=A/>H>FF<%:6!?HCB#**=;!3;:(F=
@r4879
ATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGNNTGCGATAATAAGTGTTGGTAACCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTANGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCA
+
=<BD%?-'#4.<$C04(7AF;8;D#5)0=A%<('@H,A//C.+H<*B*EB?A,38C8%;DC6H1&4E+.=%37:5;2;/A=&:G13HF-.,@%E*&>'6/09;1G(?C,@@)#=@'!'$807B$"FE'94HA>8@)C"A-'4E+>?+B?9A&<*9@*3F)00+9!4%<)?C7*-G:A4(/&9F7D;2BE-D#'5%62E*4"9$$*AA=/'/*:+E*0/F:<0>"A70!E'7:=5<EB,.5B*<F'F+FF*:>DB#(*&88H<*.C%*#H=53#5D@59:H#*60#(&/58BAH'6-99>;3CD:=.C8,5-8%D>&>.;C>3E#D$915;;?4?23@D5"@*8(-+)';?.&"HC
@r4880
CGTCCGGCTNCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGG
+
('+()!**)")'+&%%+)$!+))&"&!'*%$&+&'%!%!)()#"&")"&"&(*%(+++
@r4881
AGACCAAAGACGGCAAACATTATGTCGCAGGTANTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTA
+
$+"(>0G58"'@6./F%-2<3(%#(>7*FDD89H65?/8;*H<4@6.'1C%H%%E;=.-$BD*"+:=/08G6@?(F*;DH9:E5FC>--?+A2E:*02/#4$
@r4882
TTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATC
+
:07>F5!-D/H#.49A>A!3?<!?<:G-)8%@',H;8E:BG4/D#;$",:(G-"G<@E>48H?05
@r4883
GNGGNANANNANNTCGGAACCGGCGCGTTTCTGGTGGCGATGTCCCTGTGGCATAACNAT
+
$%'%)(&(##$$"#$(*&++')#$&"&'!&)%(*"#*+#%+!$'*#(#*'%%$#&+$*$*
@r4884
CCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAG
+
)8%H=1BF7/C)?':>3&?-=H+*2&75AA3?E:188F7AC@0A.!=&?39C%!&.4F)-*&AA/@0A-/&$."6GE!229%4F=6'C:'==)1G-,0CC34=5?0@=:D@*>&:
@r4885
ATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGNCTTCATTAAGGGCTNCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTNGCATCTTAATGCGTTT
+
G?B;F:4!B;;32F7)*%:7.0C)5/00!%6?CH<F"A>E&C'69")=6&A("C.+'H/'+F%+HDF$<A=4HC-A5C;B/@?H2%9%?E-%)7=;#E98/4)(@4$,+@>:/:5#1(2">3.*.E6!+$!H1EG;A6=8<59*/;/&!-A?F?$04"<H>'?2.53/G?$H4)7>'G,+#
@r4886
CCAGTTTCAGGGCAAAACTCAGCTTACNGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGNTCAATCTGTTTAACGGCTTCA
+
$G(;$3G?$-,C/:E'H>7H?EG'%0#:=&E3012C"?,-$413<2BF2@95&;6E$/6A-%+&@<7#22C.-)D?>":F1GH&-<H5=";A5<3?2*%'.:;&6HB7??0)6E5333+7FG6,!E+=D5*D71'E3"*8)72BA-?6>:F9C3"4=9+18$8F/7"D<-4@;!F6)F2B5'0/7#'9.4*#3F!)*/93"7)%934.
@r4887
TTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGNGCTGTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGA
+
0EC2'+*%F7G.-93.5>:CB9E-C&1D(?D>E3A:A(A&*";:),?D.;.DBD(#15'&..EC7B'<(%+D+<@7=7H0:($H8C0C'(6GF8%;,98@40('!EDA!*;=H"2&/%G;AH5=DE6F//;.-C+0#49@H3;D-A)G=:+
@r4888
GTGTCCGTGTGAACCAATACTGAAAGAATGGGNATGAGCACCGATAACAACCGGATGCTGGTGCGCACTAATACCAACTGTATGCGCATGTGCACCGGCACTCACGG
+
D.+0:3#*';C@+3E0H)%%'!,A0C?&3G$;6*+7*/H7.C3+$CA,,'F?#%4>2BDC3@;/C#0'D74AH!+0F(C,6C!#!D$H?+1H-,-A*8(?6;;C.*D
@r4889
AAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACT
+
<DA$-+&+-=-GF/:$*E?&"<6<4)G05D!'@4:#E=0;9/42F'><F"0A+7@4,1,4*C@1;;0<-'F0B74'@,B$6-#!/'-.6!H>!)C2+4"?2-E!!),8H<&$BH>;@)G%#<GE4;7<E3<D5B@FG9):'F#?9%<5!&3-/4D-7%#F8?:8H&$5:$E%9A/
@r4890
NCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGGCCTCGCCGGCAANACTCGTAAACCATATCAACCAGCTCGCTGACGTTTGGCAGTCCGGCGGTAATGGATGCTTCTTCC
+
&)++*!%"#%%+%*&)#*!*+&!)($'+$$""*'&*$'%'!***"%!#(#""&'")(""""'+$*$*&!%$"")!')$$&)+!"'')*)+(!$%)$!&%+'+&#$+()$(+%&&*#'*&%
@r4891
CCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACNATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCT
+
=D.&G"B@!@'.;!<.G)4:-)3:E5;#D@#0=:1*ED$:)*2+2&F>F=#A.0:34);(-5*8=H@>2-:!H24)+.4+-BAG#:4F>F+C"6;:D0%4-D:09*&6<2&#530'/,,'9B=H?2BB(=*3''/<#8!/F)F",?0;"<98+@!&)+@%6+::46
@r4892
CAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGA
+
@9H+%':?7/E68F2F&D;8HEG#0G.&>-E<D,>09A;)&F
@r4893
GACTTTGCGATGTACTTGACACTTCAGGAGTGGAACGCACGCCAGCNACGTCCAAGAAGCGTTGAAACAGTTCGTCGATGGGTTNGGGAATGCAGGAT
+
0+$'>,37G30*&?E>%&'37!=H/#2,;F):(+;,(+><*:7*9F$>@#+66,'4?B:;!G(%"D8426"@;H1-81"C0";>=&(462,0%-3)0A
@r4894
GGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGNAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGNAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGNTATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTNANCGTNGGGGTCGGTTATAANTTCTGATTAGCCAGGTAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAAT
+
(E7,&4B<=D%.#/"-5((@?@055>#2;=/!,>!*!@*'*$?$;(79A'H@884F+$54=3.C:8<(7<E?';7+;!+')!C3'F%#9?#1.#(9F&)3G),<5&:)%'H*0"/3./F2;B-!);2<@DB22CA?0B7C)@6,68&@.G!0$<4F#F21<)$=9!,+9/=?$7B7>):-%9=CB(%!)?4%6!**+A*D%C?&@254":02+E%AGC?%98E8:$F5(,B<AG10FG'?.B(*4$*:&%41@29"+C?A?4#,33#59AEGF:%9<F;1,'3!-2=9?)"50D.D9
@r4895
TTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAATGGAGTCATAGAACTTCCANTATTCTCCTGAAG
+
21</+#H4992+',5"C$!;C$#A#&63(-&='&)C%6B$8#,C,$1'5"//=<";,03;46048/FH17$'?>$=,6)E@"$.:+
@r4896
CATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAANACTGTGATGACCATTTCGGGCGAGGGAATTAC
+
0(9;,1:"CA%AB&*>0>'$"&(<(%!7,-C"@!EH4HCC&<-%&-2(E)@02,B<C'*%0A.&8.$/0-F7"38:>0<'*'&;==-":
@r4897
GACGGNNTTTGANCCCNNGTGNGGNANGGACAGCAACGGCAATACACACATTACGCATCGTTCACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATTACCATAACCTGCACATCGCTGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTG
+
$)&#'%%*$"#*%#*%"(#"&#*%!#%*++&(''!!$*'(""&*&*!%$()%*$##&*)*!&(%#%'$+$)!+++%+*%%!))(%*+#!!++()'%#)(##$!"#"*%!#*%%!(+!*+)()*&&"&"#&)&&!'%!%*$)'($'+%"%%%'*(*"*%)'(#$(*#'($##!*)++&"*$)$"!""$)#(+(&%((#'('"!&"+$'%'&+'*!"')*$'&+*))%'#
@r4898
AGGCCAACATTGAGTTATTTTCAGGACACAAACACAANCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAA
+
#09A!C!668B;91,+@/-F#,5,E70))#!>%55).:4;=6;'1F";,0:C"4.77H;A-$G"H%AE=+/(;DH&&!,&H/$E5F58.'4/*C9"G62:!?E1
@r4899
NNCCCTTTGGGATTCTTGACTCGACAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGNTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATNT
+
$+)#*"#()*(&&#"$&"%+'')&!""!&*+&($&()$+(%))!*#$$)*#*&+$$!&(%)#%++*%*$%!*#$'(++$)((&()!!(&+)$()$!!*"+)'&("($$($$!#**###*%%'$&(&%%&'!$'*$#+!#+)&$(
@r4900
TCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTT
+
)11/#>#5H!&-0GFB?"#(;<2&7+/%.%'5B*4FECA5H)@A@3:*,/H.,6<018C>;#91E-A(*,6E7<0!'6/*=9=8!H'>D7&/)
@r4901
GNNTAACAACGACGGCACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCGGTGTATGACATGGNCCGCAAGGGTGCCCGTGATGAAATTCAGACACAGATGC
+
(#(%+"+&'((*)!##"!!+&&)&"'$!%($''&'(%+)!'%*$$&#*!##'$%+'!"+'+$$('*")%$!'""*"+"''$")())%%&&%"&&&")!+'!%('
@r4902
TGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTA
+
F6;B50(=?!41E2;1-'=20C0<D1?+%8#"840)40(.='D"7*E!,F</'%@50&1>:*$?B65A)B/2@C=C)@"$0BFF*7B%$8=-
@r4903
GACCCGTAAAGTNATAATGATTATCATCTNCATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAA
+
5B6B!H+G*<-,"6E9@*AF.+F8:+1."C%34/25=0";E>'B./(.G9'?/A>>;/*'+(#@2F2*28"$28CC*BC'FD(C=<,2B16+,0!=:"3A-0"%9:5H,7FB0&>C>@>2#E&<;3H
@r4904
ACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGAGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCATTGGATGCACGTAAATCCCGTCTCTCAGGATGNCGAATGACCAAAGNGACTCAATCAA
+
6>*0+<A>!2@-!G)62FF(1E'9):$#3/,02&!'5=A?),F;*'>(9>'(A(6()?8('30B(H'C:.*9,G.=6=E1"4833-!8,$/*&:,>!3!G(6/?G>E?<0.?F31(G'?/+$;)05H@849("6&D%"&'!454'?$95?AH=<4"B#&#A.'.!;&6'!17+A-8D2CA?+=)1B5
@r4905
ATACTATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTNGGAACCTCTTGCAGTACTACTGGGGAATGANTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATATAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGAT
+
#(%!*#'%+$*((*($%'*"!&!#+$%#'$&*"+*)$&%)+'+&!)((()!#%&&$!*+!'&()#!&&')'!!+!+'')$#&$$&(#)!#'*"$+!#)%'*$*+))"'+(#(#'"!)$)+#'%%*(!+%!+&%%*%*$&&"'"!(+&""$++&"#"+'++&'))"(#()")'!)%+&'('$$$$&$)+&'(#$$$*+"'*!!#('(#$$$()'))')$(+)''('*%$)#)(%#%#&#")&"'!&%')#)($+)#+)"*$(+""&$$'%$$**)#&#*!&&"&"
@r4906
GAGCACGAACCTGGTTTTGAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTT
+
A3&!F5.G>,@9%8?8;)"3<:0A:3.C*=@*G(DD:F<93!/FFD:F('=.C6?G5;1#C5&@!0>>-!;-,
@r4907
AANTCTAGCNCAGCAGNGGAATCAAGCAGANGACACTCATAAAT
+
$$#%'#$("((%'))*#+)()*"&"$(*&+%#"!$*!$%)(+**
@r4908
ATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTGAACCCATTGACCTCCTACCCCGTAATAGCGATGCGNAATGATGTCGATAGTNACTAACGGGTCTTGTTCGATTAACTGCGGCAGAAACTCTTCC
+
7$&*!)4"(/*<'1A+%36,*F?$>4-9;))<F,>=0A"G9:2"B<5:F9.?8:@*3+*%@G1=F<,F"H!>.(2H@!<',<>A;<=>F=&"3-#A"49.(@5%EC7A%@>=..A$>?7+,0;9#-A@'2/=,(HD#>
@r4909
TTGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGATATATGCAAATTTCGTTTCCGGA
+
-=23>G?6.4'9H*C;-6%@EEB!$H9!/--E%<A54-4F)?7;G37#&CB;%.+6FED+$>/$A*A#GF/7)26=';?.3>E;9BB.2
@r4910
GCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGAC
+
3=EB/0&B.:::F<06,,B3(#<5"?D(')'?5G-H46;D%.;B(6"!7=3;>$$686G2/<;3>F1;-6$08/8<#4;99?4G;)5*A5&#
@r4911
TTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGCGAAACAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAANCGCTA
+
;>HG;9C&E9)&G2&G+9'*63=//?-BC"6+H2+.%01'*?&:CA%(#@58<:*2''7%!;-?$D3,!'5#5!:CBF;'1*2(%+,3!76G;8"D5<#"1H!7?$&&?184+,)F/7%#B&:*A$)"7D;5(:42A6,(F++.6$)!C3:'@)@A
@r4912
TGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGGTTTTTGCTGT
+
*/0=!@3@)#E?+DA&47(.:2),67E%19+(F:>&)6><F9<$/*!B6B+)%7GB9?F0+5@
@r4913
NCGNGACGGCANNNTGTTGTGACGCTGCAGCATTCGTTCGTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAG
+
"*#"'$''*&$%!!+'%&$$'+++'!$!&((*#&#%'%*$"+)%(!$$*%'#)+("&$#))")$!&*$"++&!$#$#+#+"&&*&)!&)')!&)+&')"'%)*!&'+$#(!+"#$*$*!&
@r4914
AGAAATTACCGTCACCGCCAGTTAATCCGGAGAGTTAGCNATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCA
+
=DD8+(B;D-0-B7..4>/10,973,G-)F4E76<"'#G8%#0'0@</9!$95!6--<#B.-<8!H<)-C9.238.2F/*>#G&6@.!!8$22EC?#+B%&"BC<+:$0,13%!?@5#*,9,=
@r4915
NGGNTGAACCGCTTCCCGGTGCCGTTNACTTCCCGAATAACCCGGATATTTTTGATCTGA
+
!#(!9@+8?<E<HG:>H.&!EA&F%B>6?8E'8'A4E$6-(51)+1@E+&!&F1667A7/
@r4916
CNCCGNNCACANNNNNNGTNAGGNTNNGGATNCANNNANGNTNTNCAAT
+
$!!!"#!#"$#!!!$#!$#"$"$"##!!"#!""!#"!#$$$!!#"$$$!
@r4917
NCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCAC
+
$H88E#'D:5@3%E%%AD)E@1H8-=!?'"/>5G3/6$!400F!4.<%4DH>8)$>@H2H)?1>BH/*.%2B4B3+7'A$.HC?)?0D1:H(*8/">D$/#@%"B<2=#67BE#4>/
@r4918
CACGGGTATCGCCTTCATTAAACCACGCAAGCAGCGCCTGCTGCC
+
4%(1=A*@$F&,51!:#6*=E->"4/%H/0>#3=(9E22/-H'!/
@r4919
TCTGCAACAGGTTGCCAGCGATCCGATGGTGGACGGCATTCTG
+
?H"$+2649?%&">618,?H:G&70).#?53&:$@C+(C%73,
@r4920
AATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTG
+
E07H%-4/"@68(.CA66F9@HD?.&>?#G1&B(9E**8HB3/?F05.32'F2"HGH%+**=#CD(!5G*<H6=@#BFBHH;-:.'339)157$B@&$?5@/<-@(,)11C5!2E1/.-'-H</H<!@&DE#>%>'..0+-"H'':)
@r4921
NNNACCNTCACCTTCATGGTGGTCAGTGCGNCCTGCTGATGTGCTCA
+
!!"*"(&+!"')"+!$&$(''$*"&&##)#("'(!&(&(!&%"'+&)
@r4922
ACCAGNCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCANTCAGCCAGGGCAGACAACCGGGGTGGCTGTGNACCAGCGCCAC
+
@(,&1>*@8>*/6(7=*@?*$5*C:G47A=3$*8"?7!&4F*#AB1&$3C)B*6#>&,"*=D&<H::$/*;E&9('?E;>;$!-7/#$!9,@+B,
@r4923
NTGAACNTCGNCAANGGAAACAGTTACGCCGATCCGGAGCAGGAGGTNATCAGCCGCTG
+
&)**)$#"(%")')+!$++((!(')%"#!"##+*""%+)!)!)&&(&+#&"*%+&!&#%
@r4924
GTNNTGCCGGANACCACGATGGTGCTGGGGAACACTCAGGCACGCGGTCNGCGCACCTACGGCTGCATTCAGGAGGCGGACGCACAGAGCGAAGGNATTAACGCCTCTGCCCGGTACCCGANAAACTGGGTGACCNCCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCNGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGNCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACNAAAGATGAACTGATT
+
#%#)%#))*()*)!+#)%'!&%+"%&)*"#%(%""%)!%%("""#$$&'+&)%""'&'($"*+#&"$"%&""*!(%)#***)&)*)$"#+$(+%*"+'#&+&+&)!!#"#*$!"'&*!&!+"!$)##&%$"!#$*)#$!*'%&**'#))#$#)*+")%%"!%&#$#("$&")"%$+#((!)&')#(($&!'%*!')()*'#+(+)'$(!&&&")$$!*&+&($'&*(()!(!*#!***)#!$("*)!$$%"!$"'%#!"(("###)'#$''#(+''")&!*+*'%+%"!#**"
@r4925
CCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATNTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCC
+
<1EB!+?9!3%B:.H!9"$7*@(#'67G'/4+3(9<)8C!@-F<*E74)(+>(-5<19&95)&-1:7:1$%*A3>9!7&"804-@?424+.7'A<H0!EC<<BH&D'1"4*?.D)#G7;+:A:'C0+F&2;&1$0!*-733!2-0EE&/0C2;:*/%-9:*B&H='/&+):(3$7'2'='B7B)!(F6F##DC6#D8D?<.5D=$0$B+1,F/5-5%G,CE>?)G9
@r4926
CCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCT
+
C%E7#<F(+&E,G*1;G+,5&<>.+>A=84",67-)4B>4.=2-6D-1<B4<)%F23F
@r4927
CTGGTACGNAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAANAAGCCCGTGCCTTTTCCCGCGAGGTTG
+
F":.G5;8&$HCF#-08A.5%28G;'(0'-?B>8=$=F=D'/<;8&<&B..,5G(-:+41878&:+<7150DH4ED!A/(05;#9?G5E70>FF>!.)4E$;!3#B36-(93)@1A9E=24=B93>'*4.3,:90&+C11DEH7<2!'
@r4928
CGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTNCGCCGGACTAAGTAGCAANCTCGCTTATATAACGAGCGTGTTTATC
+
6"9F8CC?1-B""HE"B,((2:A5348>3B43/E-5'6<#.A$#=E&5CG+89.=@#A:EE!:)D-'+E/4(767=4!5#G2<1.0C!*G,'
@r4929
GCGCGCATCTGNCTTTACGGGGATTTACAACGNTTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAG
+
E:$H%-BAF3@>1H9@FB!=?&AED.6%1@6$/5B/,"3.@",B)7+4?/%&.H#66:)(7C99CC9<HEC'+!"8G--?&;?$0#0-"6F+(D-A=9'
@r4930
CGGNNNTGNNNNCGTCCCGCCCGGCAATCNGTACCTGATACCAGCCGTANCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGNTGTAAATCCCCGTAAAGGCANN
+
())%#&&*"#'#+)$&!%*&*''&($!&%$)*)&*"'%#++&#'+**%$)#'(#&$*&+*""*%)&$!+&!())()!''$$+*'#)&#%)'$*"#++#&(*(&')")!)**$*&#+*!("#+%'")'$)*%&"(+($!#(*(($()''$%#**""(*+#(*%$!&#&!
@r4931
TCGCCCGCAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCNGCCTGCAGGATTTTCCCGGCTTTNAGTGCCTTGTTCAGTTCNTCCTGACGGGCGGTATATCNCTCCAGCGGCGTCNGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGNCGTGACGCTTCGGTATGGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCC
+
$6!*4!D0.#11,%64;,FB16%>'%@:06CE1:+?7B;!%$63+H.!E)"$,',:7@"<B9*)-H8#@**@.6#%+D*8.1,)>7C>1',G"FA6,66E)=$)/)5,,&C3EBF7:'-";.>18/B$5?1..CD&CF4=<>4FA!GD,G:4-=(-E7F4*D;(A-$?;+/7+G0**-%94*,:=1.#0<+(??645/'!#<')"1*F.//3'",D9>*H5((HG5A/+9#")-D614;0!,D<@$A,3=@&8GH8@C>:=)4H"@#'%."D7&-2-6<:7D)-:/3.G1$'F"."':6-6*#?(*8@'C/+.&9>>A,$<16
@r4932
TTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGT
+
1H)444(E*$/3?;HD$;@(H..)(,H"@:(5?3<0C@;H78A,,;D(2"4-$<#7-)!%'/&=3'7*#?56'9.&*$
@r4933
ATCNNGCTGGCGCAACGTGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGANGGA
+
&)&#!#(%!$+(+)$'*'!)$'!&#'*&+!%#(*!'!"**%**%))!+(")**+$'#+$#"$'$'++!$('#&'(!"$($*"#+(+!(*'&#
@r4934
GAATATAGTTCAACCGCAACTTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAA
+
!+*G?2'!7A5/1H0-F8))*=%*(G6H*:=8%H5GB0+F$)056G.B$D<;9D+
@r4935
NNNTNTNANCTCNCAATTACANNGNNNNTNCGNNCGNGANTCTCATNNCATTAAA
+
!!"##$!$#$!$!"""""$#$!#$#!!$""$$!!$#$"$""!!##!#"$$""$$"
@r4936
CTGCGGGGNATAGTCGCTTCACGCTGGCGTGGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGG
+
'&)*"*&!%##$""$+"*$#(#%'##!#"*#*$!++%*)(*+$'*$*(')#!!)!%'*#%#$'))!!&&(%)#+*##&(#$+)(*"(')%&"+(+#!+*$'%+$''#!%&!*')('!#%#!'++)*('"&%&)$#()&!(+*&
@r4937
TGAATGAACGAGGCGCGCCCGCCGGGTAACTCACAGGGTANCCATGTCCATTTCTGNG
+
G:+66F*@26#>D(@C96879?'GA=>=//7>+AB57F6GE(3,$9<7+6E4:#@C7$
@r4938
TGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCANTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGC
+
F81(C:/?!A9131.%D'5$1$:!370E9>6+@(=*4F<FB,$+3%H-5:A5(&9D6G=0733(;A=+6;HG82'%,)'%793+0&3;@/B)*8)1'H<4%B.$9?!74@?)#H-/E>-G))(5-E!':-/.@';!16":)-4G75!(/A%D.,6##(D:4E,
@r4939
GGATTGCAATCATGGTTCCTGNATATGATGACAATGTAGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAAAAGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTA
+
C9"?H?1@A7H?>'5HDA</5*?)<C7)*6ED)GC+:#2DD$-GE/+"6+64;5?$8*3'C0&0/A:6=DE63GD66&:GHA$<-%6E2*<"-#F8)?$;2-G%*>0@$?<'&6*;3#7>-04!+0%C:+F<*/FC9<&14;:4D"*76#:"&4<.12"$.3E$1-HD)EC/.50/".2%*6*$H(/"0D0?GB-G2A4,A1,5=''@G):=)9#7!H$E8=G3/;+DH3:$6%,*H,B</*3-D@)0<+6(,?-?!3/.C)--/DB/5E#!A
@r4940
CGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCC
+
5:0$:;*.46/B!:6'5'#&9#%8(./G"10"0'G39(B=H7=
@r4941
NCGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAAGAACTCGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATGGCCACNTCCGTCAACCAGGCTTATCAGCGNGGTACNGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCANCGTCCGGGTCTGGCTGTTCACCGNCAGCACACGACCANCNGTGCTGANACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCCACGCTGAAATCCA
+
$(+#)"+#$!+)*'&!#%&'!&&#("'$#"+$*!$)&(*&)"#+#''!**$+*%$&%#*"((!#**%&!'!!$(")((+$+!"'$"(**#!('#&(!)$&"")%!&'%"(!)))**%)((#$+$)')#"*+#!#+%"#&!%!(%"(#+(##&")%+$('&(+#%*"*&#++!%!*$()+$#+&'&$$($%!+()#)*')!!'*)(+!&"%!+$&"*#*'#!($#"#%%*$&'+!&!!%$(+))"(%#**$&%$%!!*)!%*!)+%&&)+%"#)&#!+%")$)*'*!$%!#(*"'%%+*)%'#($')%+(*)%##&'#"')#%(!'+!#($!$&((*)!!#')*(+(+!)*!#%)'+&&#$"(&$($
@r4942
ATGAAAAAACTAACCTTTGAAATTCGANCTCCANCACATCACCAAAACGCTATTCNCGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAANCATTCAGGAACGCAACCGCAGCTTAGACCAAAACNGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGCTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACTTTGC
+
++((+")*+(+'$*!)($(#*$(#%!!*"&"%!&&'$#&+")%('"(#(()"%**'++)%)*"$)%''$)%(#('*%+')!%+!+%%&#+#%('+!('+#%$$(#&)#$'%+'+!"!*(#*))#''#&!$'%##!*+)))"&'#&*"$(**%*#!!")(*+%$(!"#!!(#!*"!)##&"!"+'&+'%#)(%(*)$'%(%!')"!*%###'!!)($()!$')%&+%*!!!+%$"$##&('*$%!%&!#+'!)"&$&!&$("'(%$"!#'
@r4943
GTTAACAAAGTAATCATCCTTGCGCNGATTCCAGATGTCGTCTGCTTTCTTATACNCAGCCTCNGCC
+
&$+**!%&&+("$'$&)*%*"(++#*!(&+#+$)*$##)#+$"'&*$*!%%%(!"%%$$)*%''&#&
@r4944
TTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTNCAGTTGAAGATATTAAGAACAGCCTC
+
D9B1>A-96)+F"&<H$!::4-C2.0E7.8'F9B/@>)(0F@?+4GG'.>'5!--(>")5#-$E=4,4).615F*?4E%@"
@r4945
GTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTTCCCCCAATAA
+
1G07;9$!<-!G*5++D2&1%A844.*<G/-$8%A+#93.A8#1/&H-28;3)E29:-.D!1:&5>#G%=%
@r4946
GTTCATTCCACGGACAAAAACAGAAAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCC
+
<2F7G=25/D*&,+8(C4>?F.65-(1!9+->@*1<*E8:"48;<*#-B5<+BG3:!>&/:B+#2HD$!.<+<B5'!/&84.B%9C!;H<E0#@E",'F*>2;6D%("95C*-2F657EF:03907:17-&%E>=G&9/6+2ECA!A.+")45#9#?.E+"CH%5/+H=:4:*>"=)7?&21>39
@r4947
TCACCGTGACCGATGACCATCCCTTTGATCGCCAGATANTAGTGCTTCCGCTGANGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACNAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACGCTNACGTCCACACGGCATTCGGCAGATATTCC
+
10.$+-"$/E7"HBC3"H@<,C(+$734&"4.1.C6,:%@BB%/DHG-4E&391#-;E%%+::)<9*<2;"$'(<+"%!$E;GF?>4@?2-GF*0;D>6(9#'E"5-&GE*$&.BBA*0",A'DG3FD(H2#D8!;6?5/0:26?,+.0:,1(44#(;*%6>=8./9<<7'%;;+<$3=;;:25<=4(!:BA8:%3)<H<!56(''AB(2*7D<8<+?H=,&-%#*:BH%G!2F?<(D"7<>49$H,:DF8)F2::D-?G",-(2B;
@r4948
TGGATCAAACACTTATGGCTATCCAGANTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGAGGTTTCGTGACGCCGTCGACACNTATAAAAAATGGATATTAATACTGAAACTGAGATCACGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGNATTTCGCGG
+
E4/C<=666=H:4)3,C012)/F2<,5+?)+(#-GH677FF$.?G<E"?4>10)D";-E"9E*!-D5G"(*FC%H>:@FB'E19*1(!@4:9.%)G,&,.91:H'-?''&)1H$/=C!3D',%C,.CDH#DEA";##7.2>9=3'EFG)"'H$"5G+*B:GG:B:"1?HB*A3;C('6+%F1"
@r4949
CGCNCNGAGTGNGTNNGNGAGNNNTNACNNGNACCCNNNNGTTNNCCAG
+
$!%"$#*$)!'"*&"(")%'%$'%'#'(#&*'%)"&"#"")$$#%#%"&
@r4950
CACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCNCTTCCCGAATANCCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAA
+
+++&"%'"*')#+#)*&%&+$))'%"'($""'$'!#*%**'""##!$("""%'+'"(%!%*+#&''+!(*&$%"%+&+%#+&&$)*%*'))#")"+)(()
@r4951
GCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGC
+
3%14((-0"A@&="H,7>&@!#!,0)61:3517(H)!/>'%+<E:5FB&2+9?F@G9?:HA$CF%-2*6/'6$7A#H9*4:.>@$D&G&6H<"@:B%3EA7H5F96.!:;4=9E!(
@r4952
CAAGAATCNCAAAGGGATATTTTCGATCGCTTGTTTCAGTTNCGTTTAGTGCATTTGATCCTTTTACTCCTC
+
*+C8@&AD)!;?#;24?@8GE!3;*-8"H>.'&E'>*=:6#C2.3.'?51C6GD!=&3.F$GF>)$F7!E?&
@r4953
ATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTA
+
%2%D-B.#6(@*?39:<=,0909"0C14%"<."*+!"%!>,$1#5.38(?F>.!?.D-/1"61;C(20FF80(3)$*#,5,(/4G$!-(F74.=DG4%+B.8C6,$=4:$)A7).?:=
@r4954
AGTTTTNAGGAGAAGATGGCGNNNCTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGACAGCGGG
+
$$!*#&&(!*)#"(**'(%&####')+(%)'+%#)'&#)(&"#&&&*"*#"!("%(*&#!'*)#'+!($$)"%($('+"++*&"*('&%!(+("&'%!#*"%)!*)#*&(&(&$$*%%!'"+"($
@r4955
NACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGT
+
!?1FB$'*+%G>&GH8!/3!=*F2(H%<7#3FB8-4:AHB7/%.<*!28F0?B7C51<:/$6(D<"A-<.
@r4956
NTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACA
+
!*+%%!)+&!'+""%#+%)$"%$!(&'+%!#$*'("")+(!&#"$+'"#(*!*&)!"("$#&*&&$'#&"+*(*$"%
@r4957
CNACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGA
+
'$.0!=3*8:,BGG8&"4%<1/3#H;43@7-/2</,$,;H1A.4!'5/*$=G2F,+74H*"!H&>')EE+>$,)G:8G6-E4H5
@r4958
GTACACCACGTATTCNGCATGAGAAATTGCCTCCGTGGGCCNGGTGGTAAGNACTTCCTGCTCAATCTGTTTAACGGCTTCAT
+
CG--=$#(!6+C&@(;=1A#&26/D'H@?>EF2G#(D:H$0095%6;?*=11/.:<47A63.H3E9&9-@C.'9#2@H"F&H=
@r4959
CCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCA
+
-6'1E)H5C/EA%%*B"F'7!=''6*-?*+5@&!H?/G"B)=G;-1%/F2CDF:?$<"FB?38A5/-7B)0/9;&!#*;$%5>B4*)155G5')4"
@r4960
AAGCATCCGTTACCGCCNGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTANGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTGATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTNCCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGT
+
,41)3,$+.B!<F&$/?B$%'6>DH#65":2*+6)'E$268/0$B-).%,%0?#F11H6#@':79*(H".#,&A?<AD>"GA!#$:6@*<5F9;(7:/8:(2$##H";<"B<AAH,'#,=;*-1?:D#5/08.47;<?,=D?=#5+&?)(8/#<3!E),!2*G<;1B',<*E7E0.*HC>(=?&5-5D
@r4961
ATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACC
+
C?2=;-2+5F".#,@:)7H769$$#-*>7*54&2D+89&1=8>3D#88:?2
@r4962
TTTATTTGGGGGAGAGGGANGTCATGAAAAAACTAACCTTTGAAA
+
A9**>@'.HG2(A&$G2#5540)'?G@,%.8,7&&/GH,-,9;C?
@r4963
AGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCGAAAAAGCCAGTGA
+
1/'.13&"C"G,>G;,%129"9E(+5794>E0;+:,+1A!D6/",@>5E,B6<%6EF34CBCHG
@r4964
AGTTCCCCGTCANGGCTGTGGACATAGTTAATCCGGGAATACAATGACGATTCATCGCACCTGACATACATTAATAA
+
;D6F)=?(E!>G13@HGA'3.?@/2&>)?3*H;?9D<C9:D)4410+9E(C%%=3+/B%-ED0<;(=.EH-H!,H2:
@r4965
ACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTG
+
B!78EC5<=(;<)BG88."$!65-=@31$G"=)@$@89/,',*H(//5>2AB=B;;@H29=2$/,D83B*!(7:2<<A,-$9C2?@?9
@r4966
ANCTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATT
+
(#849&02<3HH=%H>@0B5&<C8E9#+?:!"+4DD!89<(0&
@r4967
ATATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACT
+
E:!A=!,&F<G@6.$D34A+"+'<,,:!./4.4=B:/3%93,.&33
@r4968
GCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATCGAACAGCAACCATTACAGGAAGTTTA
+
DBG(@5A'#D--C"<(.:@"=)9A%4DB!3).8GHH6"EF6$8C3</*%&'=7$C"+E$:')$G04"B;89*-?A$51$??9<ECGH
@r4969
GGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGG
+
@=%.D9E6/B,*1>4B1.:34'9F.FD(,)3=G!F33<.C)G4<H3$BE*(!&*F+%DB/6:+
@r4970
CCTNTGNNTGATNCGTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATNTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGCTTGTNTCCTGAAAATAACTCAATGTTGGCCTGNATAGCTTCAGTGACTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTANCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAA
+
#!*!$*#()+!!)%#)"+"&&!!'*+"!##$&!!$%++(#+&&*)$%+)''")"""("+(*'!($)%")&"&*))))+!&("+)'*'&+'!#*+)!'!+%+&!#$+(&(*(()%*")!*!")"+$)&$#&')$+&($%%*(##*()"+'(*$#!!+%!+"'(&##$&&'$&(%%&*'!%')$&#"%#)$#&"'+%+")'*'%!($'*$+*!(%%"&%"'*)+('$((#*!))$&""$+'*"$')*+(#&&"!
@r4971
NNACNGTATGNNTNANNTGTATTCAGAAAATGATTATCAAGCCCTGNATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTACCGGTGCGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAA
+
#!$)"$*%'"!#"""%!$$*%+''&''*''$%+%##(*&($$*$*%'%#$'&')*'&+*'%($%")!%'#!$*#%++#&(!+%!)*'+))"&"($%(+(+"!#'*'&*($"'+$((*+$)""!(!#(%+%"#"#'!&!*("%(()')!%*$+*')!%%&$%*&((*!#$(!(")%++!+")!&+'%"*+&&'*#$(#&(+&!&+(#%+('++&))#"!"(!
@r4972
GAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGNGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCA
+
H=-;9C@+(*.2-487':>/C5.4;C!+17+*H&D(B<(!>?<?38*,)FE=D+2E;!@"@"#C-$>C=(-#(6-H$"3:@35#.C=16HB3@";0*/2-A//-#5CH(.':4%:7"38=9%#795-",?%85(&F:1(C
@r4973
NATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTNCGATATGNAGCTCCGCC
+
&2+1+:&/8$7*/#D8-D/!5H<&D<34?A;*/)5<!+HA>@9D0F+/?3?1=;=G79>=$C1==/0
@r4974
GTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTT
+
.686-@69;),#1B!6104%8$E,?')?#*%%7/=E7'!(=9D/*H0/?-?FD%47#.%D>#EF'D;#,/9H.-#BC2+
@r4975
GATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAACTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTNCCTGTANTGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACG
+
*5&,)"F3(<H!(2EG4(B64/3?B4-/C"491G)AH%EG&9,6285>&G1+B7F.3A%DB);#AB-)+F2BC'&.!BD:><>"&47:2,,2#@*>G*-?:GA/:(15)<H-&!1B!8$:?@H9($F:4$,H;<'+)11B:E<=/@7E3G9)8(.!1+$8B-#&+@::6,E/.,!"
@r4976
TCNANGTCNGNAAGCNNAATCNANTNAGGGTCACCGCTNCCCTTATAAACCCA
+
%#!'!&%*#&!'%%)#%$"'$##$+"'')!+()&('&")*'%'%#")+*'%+(
@r4977
ATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTANATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCANTTTTTATGTTGAATGCCCGGCGAACTGG
+
'9@.B5#75)):F*CHE*"(;H%3>!?B'2C<6$9&;+>!0"7)?71CHEC0-A+:5=.*-+/6,*244B678)<+/>H60+*.F<"4D=<%0%>E)$B"(!
@r4978
NGGTGCGGCAGCTCCNGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCNNGTTTCGCCGGATGATGGCGGAAGTTGTCATCTCT
+
#(!#**')%#'(#"%!%&*'+$%!*&)!*#!(+$!)+&)#*!"+'&!&"$*$$&#)&+%$%$*(**%*+$"&%$%*)&#&&#"+&&+$"%!+%*)+'*%
@r4979
CCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTG
+
68;4A4%'*C-'?-;2;(&@#+$4,69,0H6.&+*F;18);AF1!1:-,)!=/;@E7=7
@r4980
CAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGCAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAA
+
(57A3"0>*/0$8!-?4AGAH4GAC5*)"2)9!68.@3>+)5='F8G;=88F"-4'?8)>$CG:,')3:##4GD&<G.@41$7:?8%2,/E9=</(2+F5-H7
@r4981
CTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCC
+
5)21?(04#+7GG"C&GA>FA4<?&&!G3#EDC<>(2%>:FEG$$'4>:CH3F"45&:4HG?-G;31(*GC$E7!>=
@r4982
GGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGANGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGG
+
=,5&?F9:#4$>E0->E*#$35.';60C.;#>'57>BE@E*H5B!?(D8E4!1"3!C/%?B8#;*?'BFA-4,*877)D;>.H<,<A!-*)2$8$69
@r4983
GCAAAGCTTTGTGTGCCACCGACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGC
+
FAG1:4>C<8&"A*5'C/"!(1&1FE>:$(7"+#046A*80#917.&G=27@4>$2.F(='&E$%$E.#>@
@r4984
AATATGTTGCCATCCGTGGGAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGAANTGCACCACCAGAGCGTCATAC
+
1,3@+/,>*;/B"?<"1;&2H31$:!81;4H2C/D>-;A?,A,:?@;.0'%@3(=0&=:&?A#C>)@#'*95(-E/%/AHFA72A>A4C?"<<+65$/7$AE*EF)
@r4985
TAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGTATATCAATGAAGGAAACACTTGATAAATGCAAAGAGAATCT
+
.20/@*;C!;7+=@7EE?F";E<"%G;=.0?<(;D.;#2=?!5D'-=7E)4#HA"C9'5&83G&?5(4+D1G#?D64GD2,B2'2<$6A8,/::7(./'3E36?!%*C055%"G<.
@r4986
GGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTG
+
4.%=*;=FF4.:1/+-.)#$:=##=>79-!@H%-B4;4@:>"?/:D+=!)<:".BH!@G<B1FF!!6B78-@56'8&%&6D'$!,8:/H.A-H2/A/.:1E
@r4987
ACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGA
+
>835**@:@=)"8'!11@>9>8/6/6!7$A5??%FBE6&:8D66?@6A'D-%6>@>?E(4;-=*%;(27#1@:)*!5
@r4988
CATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGNAGCGTGTCGAGCATCTTCATCTG
+
&'$%&+++$"%)")%#!!(!$!(#($#!!+)(*%!)!(*$)+"##(!&)!(($%*)+"*&$&$**'+
@r4989
AGTCAGGGCAGCCACAGNCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGNATACAGTTGGTATTGGTGCGCACCAGCGTCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATNGGTTCACACGGACACACCATCACCGTTAACGCTGCGNGTAACGCGGAAAAAACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCNTTCAGAATGAGTGAACANCCACGGACCATAAAAATTTATGATCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTNATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTNAACAGTGATGAGGCATCGTGGCATCTCGTTGNAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTA
+
6$<CG0*#.7B#>8")"=>:E%72#??"?"..H-&&>6(*.3C3<)6:7G76";5?!*!)8B-=G1<3B$%+'EC-F#2B(%+$9=?#@,>=EF;$,GH7C3;1-./.5,0E?@1?"6A5?&1,:)',CDD%0<8*8!(30F!,-2H+;D?5=4$!39#&/;-;&E.;B8:0G-&E4E4.*6+60#(@9DG.#E128(=B<F8*84:?7%<6388>H#2GF2,A7C.0C/)7<"D/G&92/6.A=!@4969A&(:6@*:#!16%11G.:E&%D28;<C$;4F,D)1AE7E(:863!?47*+C/9A.(0+6(E*800%E64?$2!9F(!147>$-2A3A5A.ED8C$E-;F%.F-=B9/G!12)A!"6#$@1"E<9<@C(552293=587%%/C3(&$?6(('ED"&.8=77F8&(G(0=A0%/AE,-'3B-+2@7!G2+:-92,0E3H8F')6-:%:%C>>7*!5C:#32E5":B$D$*::!H
@r4990
TGTGATAACGCCATTACCTACAAANCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAANGCGGCAATTACTGACATGCAGATGAGTCAGCGTGATGTNGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAA
+
!(+&+'"'%'!)$($"$'!%%'$&!$*+*!*&%**%%'$*'#$!#(!+&'&)*'!()#(!"&"*'*#"$)$*+#)!#*%"!)(+&)###"#%(*$)"**#'$'!$'"%%$'*$"'*%$*+%!(%(++&$$$#!)%"****(%"%%+&(#
@r4991
GTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCG
+
>H-3=..?FA#?.3$92=<7#<E/,'=<2DF($!,5&;25!1)*
@r4992
TTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGACGCCTCCAGATTATCCAGA
+
9&$;1H87B+9>H/H)2FC+(E&9<+18%@+<)2''C%-0-09<'',%GEH@;C8-;?F(+8FG&F-A97.6(1B#&&679>"%15F;B7;1CB.'FA.
@r4993
CTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCNTGTATCTCGTGCGG
+
//<*,B@E(EH:%>$+"F-*+D>?7''E)CFDH.@+H&-*!="4-A-+G!"4&0:(38>(783<75DG10A@0CC&5<
@r4994
TGCTGCATTTATCCTTCGTGATATCGNACGTTGGCTGGTCATATTCAT
+
021!()A!3;D%HCF1$?,E@#D<?A/#2,5((;E4=@?047"A/<%#
@r4995
NTAGCCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTC
+
!>;>)2:2B7?5'):C7,#,4,G2/@9BEG<74'&*=-.?25;#F)#=F5G45?-:C$;?!")5,@/)A,-+%4
@r4996
TACCAAAACAAATGACAGGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGA
+
+-!9<*G*'*"H+B1('.!B.A.!7;3/:32'&8+520FC:F+)35"4%!DC67>EB+758>>"B".5D<*(F!FD&&;"999>@3@
@r4997
GGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGANTTCTCGCTGTAGGGGTACACGAGNACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACT
+
(F<FE49FD&"/9$!5:'H(5;H643!$&6C:G#5D/'+$G1?!@(4?6FA@75/;=+(?8545&&:7A1HH,7A)E$'GG+EA)>'2$H&4=$0,,(3EDF<"6!"CFDC-329ED:3/$3CCC21$:>FH/G@7="#"3BD&C5
@r4998
AAGGCGGCGAGCGCGGCTNTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGT
+
$B:A%F70F23EH<@)EE9H)8):6C4G%DB;9/=1H)1FC@:3%,,78<$:/6./*C,)*8880H/5!?.A$$:-&B/0=??E?1+C4D02?,D;$2DF*#21+;;/&*
@r4999
NAAGGATGCCAGTGATAAGTGGAATGCCNTGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGNCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTNTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAAT
+
#65E82+;5BFHF781B1B$%=H/0#?!H%EDDG'1H/+H:8FD98@%0@:GE,FF)><'/2H=>A;4;D0G4@1(.0G%!,#,5+420@2GF*E@>/)8+F5DBA4>;C10&3G)$9#'5)*&-4316G(*FGE#A-;<+E:A'$=D)0837G0&71&9A/6"0>3B:F1!
@r5000
GATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGACAGACTCGCGGTGCAAATGTGTTTAACAGCGTGATGNAG
+
/?48=@$?7*;C*'(AF4(57F#G;9(.686)$/@F!:<42152C/G>92-4947:*'2=.A,/8C"5H/D42+C*DA?GF0F"-6H&#6E<H&:?&C0B+==C8G#B@$$<,G-33?67BE&%,/8%
@r5001
NCTGAAAGGGATTAACGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCNAAAGAGCAGCACAGTGATGACCGGGG
+
!$>!:;EE1,#@313/7'34B5($(-"522<#&G!365;G7!:5E9(G"+>EC771G%95'G#%>:*A%HAF0/*>0-!2#5'@<67B'DE"5(A?#FGE9#*G@FB&=(
@r5002
TGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTNCCTGAAGTCTTTCATCTATAATTGGCATTGTATN
+
*,)"'78<&BE2*(>&B6&)%'::2E2>4%<5,5,-DA"+E7A1%;;(4..*GEE871*8!2#9+%!B0<%4>,*
@r5003
ACTGGTGTGTTCAGCNAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCC
+
@%<E01/*6C48A@H89B-1D*EH=6(91@B3A%8H.D4!)77'>@8?.G'2E#?2@B6$BB@*""0B%7#
@r5004
TGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGNGTCG
+
)*1D$*&>&DHC<%$450$E/,<E9'"(<5;,?=6<GA>+1C#60
@r5005
AATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATGCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCNGCCAGCGGGAAATA
+
$)+"#%(&!(%"*!%'!'$&!*"#+""*"%&("(**'&")*&!%*&%+%&))(&$+'*"#!*!%#'"+)($#)##+&%"(*(+*'&$$"$')
@r5006
TCCTAATGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTG
+
H6C,9?8.''628A?7B30)824#/,"$CB&.H>"(C2<C+8"##"$5<;$.!CBB&?CB08&<E!?7);'/,&#(0(
@r5007
NGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCANAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCNTCACCTTT
+
!'##+"+)$')"''#(&$!&$"''"$!"'%(&"**!#)!&($""$+++!%'(+*&'("+)$#(($%*$&!$+#!(*(((*!)+%)""+"#"+$)(%$"%$
@r5008
AGGAGCCGACTTGTTCTTATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATNTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCANTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACNTAATGA
+
%;)*,!-4!H*E$$18"%:H24/!/$C:C@'5!92$$+9'H3/",H00/0/0-/.F39+:)0=B,4)",$"0<'%A6F-D;?-5@(".0B6>2D)9F*&-@)G%A=D16C.E/>5FB>758:>7B/,2?3$-?-4?<?4<E&!>!&%%=A9/"4:3G-3724
@r5009
CCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTGTATTCATACAACCGATGCAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGCCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACNCCATTGGTTTTGCCAGAACTGTTT
+
:;F)@:05)9?<<'H.$H"*(13D)'"/-F@D7"($G/0*%.('1!62-)A:>>#<5+'$1/2H(=,8$D?#99/9%1G&=HE,D&5>$E5,"!)=!8"D*>:&2E8?!9%#2,5>B?B0,2/65,8+$52>&-.14HG:G(%!,*5?==>!A3//*<?,/$+5*:,)C%09@C=)5.2+8F"+,8#-AC($)!"28)0@.D,*0)"((H?)5=$,=@?G79&3B(##-=0BA$+H;AF+A.?2-
@r5010
GCTCCTCGNCCGTGAAGAGAAAGAGGCAGAACCGGCAGACGACATGGAAAAANGCCTGGCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAGAAATCCATTACCCGTGCGGTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACC
+
'$!!&*%"&+%%('(+(#+$%%"''"+%*!'&(($&)&!)!*%&!(+"((!'!!&%&#$+##'#+$#'(&!$!&+&**($&#+)!($")$##(+!$%'!!&!((%&'**"$%!)$)$*)"%$)*%+'&%*'$'#(#$!"!")"')"*$!*('!)(('"!!##!##'*#)+%'&$*!**+'*$+!**#&!)%(%'"
@r5011
TTTTTTATACCAATGTTTAACATACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTNCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATGGATCATTTTTCCATTTTTCAA
+
>*<"0;F'40A*!EB%7*H4#2.$;0'+'E<.21=;<6-GH98'&#$:">,0H%!'(8%"G8A&!<+'F/D?42&+B59%HE;65&47*4%!+;B$%3%/<!4C"*&>5;GF0(B<,'?%$D64&=&%.$#?@F7EA3'@!5A?3+(33'5,-=D$"(:=$'*;9%=&).C'3F8-%7E"%
@r5012
TTGGTTGGGGCAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCATACCGAAATCACGAACGTAGAAAGCGCACTAAATCCG
+
(+&'%%+(&'*()%(%+*)**!'+#)$$)&(+)'*'*%)+#'*!"#(&#+#*#+($!%%%+("$+&$#(""+!)$))&%!+&&"'))*!#%"
@r5013
CCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCA
+
$.?)H%$<C@@*%&B0>5<814&@!2*F!C1'$:5=3+@8:7G>"
@r5014
CCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGNT
+
9.06C$=B)<>+=94HC@%/,28BF031DC0?<)*F*>%A3?B!C%%2',1
@r5015
NCCTGTCATGGGCTGTTAATNATTACCGTGATAACGCCATTACCTACAAAGCCCA
+
#*<.0A8.&/=?H-;E3#*+'D4#<3;#!E@E""HA-9H"F<9<3*(*'9C>DE-
@r5016
GCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTA
+
H4<6!1'3?*9:H1?-H@!,;5/%AB<#<E5?4!-7D<0F-F=?
@r5017
TAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATT
+
#>%<8$(3)A).&71H.G;)F8>>/(6.)3H;8;72@):$>,'(*6@A2,@7AG:BF;&.D&3>H,::@%"7F<;8D4E%C%0C4.&@%!46E9%2F52"6F(%6&79
@r5018
AAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACACCAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTNACAATGTATAAATAACAGAATAAACACTGCACTGTGTATTCATTCAAACGAGTGAATACACGGAGCAATGTCGCTCGTAACNAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATTTTTTATCTGTGAGGATATGAACAGATGTCAAA
+
,0C""C76!B1$<"#3-=@:,.$8+(*F?$.+;1DD6=0G&?296'4<7:EH>(5!F%3,.=,,8,45'=&$HHED+198G?E1DB*="G&4@'-A;$+;GG?GGB$;;2C:""&9AF!F==,E330C!:>*E!-G$AC79!(>;%)$E:%5%CF9*;.-A%-('<=3E+-<2);%&BB.<*9=6:!D3,#H752@'=%C@+:*@2(D.%CH%)DB/:-%8/FE<(5!1(.GA'B;B7$F)=@>.!!$C5$014/?6C%$(E;3/2D#%#/++()9H./.AFG@F320G<C
@r5019
AATCGGTAGTAAGCGNCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTC
+
D/52-1%=$8#8="9/6,!6.?!8A+98;;9@40C#7*%&5:FB?D#)4*30+!8C2(H/$04*>*D@H30:&GB==AB$-#=3+0C(
@r5020
CGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAG
+
93;"/@%/+%B#2BE29#7/+A,(H?@F#%=%=G284>A>4$(3-H?!<&51F73.@H.,"A#D2H'(H
@r5021
AGCACAATTGATGGTGTTACCAATTCATGGAAAAGGTNTGC
+
(560GB>G,EE(/8-=C5%/.57%,$1!+"+'6>>$)@88.
@r5022
ANCCAAACCGCTNGCGNTCNGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTCCGGCCCATATCCACC
+
%!&$#!&*))*#$)"$#**"*&+'#&$%+"%!&+'"!!((+$!$"'%+'&$%)+)*!'(%'%(+'&#+)++"#!&+**!&**'#!%$+!!("'"!*%"*$"!!!%*&$)+&#)$+%$*')#&!"*!%)'!#'*
@r5023
TGCCGAACTGCTCCGAGTCCACCTGCACGCCGANCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGT
+
,5*G:2639H+$-?'4.+1'CD&#"-5:!2=#7$A;A@?=1B723=@H;G=D/1B&->/0890/8@;.@!#<7-",E(<6&H+!>'%*C00%;042:
@r5024
AGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGNATGGCAGGAANAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTNCTTCGTTTATGCGCNGGCGGCGCTGCGCATCAGTATTTCCCGCTGGCAGCTGGATCTCAG
+
")1:$9>,*33'CB:&%/*G=="@7D#?ABH5&(9G==6"/4$E;B.*#2>+%#0%@*<F4-7:H$$0'(5:3!D1*'8?>&@HFG7=7(?9FBG/HF/'/6A;>'%&+10:+='7!"4BG"@H"*(H&A&A/1:$#'<15)3;CC9,!B48)5*?D
@r5025
ANCCCACGNGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGACAAAATGAATAAAGATCA
+
%+G1#E9-!$4$&53:!8#?55&/>3-6-)G01A"BCEF0/3"E&G6(*!E=.:!89**0-?<D6!H94;071;&FG3.02+"B2C(?>54<2?AH8;&
@r5026
CCCNNGTGTCTGTGGGATATGCTGANCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTT
+
)()!'#+'*+!()+(($"'*!#('(*%!#*+(*!$*"&()$*#*#'+)&*+*!((+%!"")('($*!''""*%*#'#*&'!%#!+*(*#+*$!+&$"*'**&#%(!!+'(##+*!'('#')$$%$"!(('$
@r5027
GCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTNAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGNGTTTTGCTGATGTGCTGGAGATCGAATT
+
B259=&2$%E<3<7#F,#!7.)37!:.F.7#G->#A%+'6D4,5H/@,/6C),7E-"2HD$-E-7.A)(?C7D*D%11/<)"'<>-,"=&/%?)*#+9=D!1;A8/H313DC$2@)&/"2<30+5*;<8<@$
@r5028
ACCTCGATTTTTTCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCA
+
<=83+01%H<9302#&$DD.29,C$$;1;."A74+5.<:--,?3'&!EF(5@,.,8H)C0EC.4#C2C+:>2)?)1''<D-A)/"#(/35
@r5029
GAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGNAGCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGANGAGGCGCAGAAGGNTTACGAACGGCTGCAGACGCCGCTGGAGAGA
+
?H+'E#6"(4/9:%":!B>)9>5/4:"30B?$9/(+-<>+9*C:<F@@C,,;"E&+18:"<;C,@>2;A0"55&&&-#<D($&).=-++@HF!)/?5=D'8@,#-551B<<H>>'@E$&DGBE7G4!9E#;
@r5030
AGCTCAACAAAACTAAGGGCATAGACAATANCTACCGATGTCTTATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTNCTGCTTCCGATTAGNAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCANGAATGTAGTGGCGGAAANGGAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCNTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCT
+
:?9/1)B#<6H4"@!"$E8-#B<5'1:@AB;@.BF'@*+%#'%;7*0@F?,94-+!19!'<2CBH-0-<C$"4AHB@?>)4+(B1-1;>29C#2;"A6;"E8#'&#D+@6E(H:;>,/!E<"?#!-E/1-D:DH86%G.+=G,7F@B4"?37:$A8C*B/*6F)/177?2(5D#"1B.'4-5@)%'75$">+($9:HE%2C0*A<E"@(F(4:H>A/HH(+$AEE4BE4'DA!64:,5!(=D48=1C6.6/,@&%/%::H>..%FECG*1#59D==),<>?(35+*4?=?(G&.1)B84>C"5;D(D"'16-65/*+-@7FEBA,=28<><D3B)>%CE8@HE"4%(<DG!G(!>,@H)!@6'E/A(@F3!&5+*2-,8)?
@r5031
AAAACGCGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCNGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCAC
+
=6)#!<H:BFF=!6/5&9515B8C+!&=(=A6;BC2.C5-%@<"FC??E)3F?,D@216)*);E8;;=0@>(@!44=,1?6$'A!)5+HDA:@+G04)D8%!*81"@3@0<5C6E
@r5032
TAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCACACCTGTCGCACTCCCGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGCGTGCGACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTC
+
1.+G%&!.-AB=(-,(:/-%#0*)EB5%.F?DFE0&:+91)&014?D1+HC8E$/<*+.>=070C<$A:!+#F.1A03D17(G$$9.67".)&&C%D@,A>,5F848B-5557;1.H2A95.3-GD8.8<&:+:%%G)"'@7!:&946C@#;(-.13)%@0:%'6)2-&DG6E?,5<C3)>:#&'<=%><?;.47A!:%1">3@22%%>8=&>4,.8,!A=,5>)@D)3$0*.';%*%A#$HC21C(1)2AA:.(
@r5033
CTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGAGGTGGTTT
+
@>+C$48"E&@/:!5A3-/0&$G&&FH=*G/%:/1%9)'<E(D37;+H'8'=F4<+=0
@r5034
GAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGNCTGCCGGGGGACGATTCATAAGTTCCNCTG
+
,.%+7G6%2'DG5C#)-?A'77:<&(=04==;7"721&G.9(/2H?=%D-<?.#-!.!<35$F=6;HF%.9!9H8='?34E",B->2?H6>;4%+#5=;A+;8@9/2'#-"'98@%G8@B.7H3F/4-/#:<61BF,&6&<1)
@r5035
AATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGNCATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTG
+
AD:#!,+//+2>?E*.-+0E@75,HE<*F$%0&#$=:$A.G%+#:#C!=G2;8*C#"*C%%C$-G2>AG*H5<6+G?"4)DC:%10$3'B1=BD3=;(@3)22:4B"13<HG.A@52<%0+D235F$$F>;)'HB<3-G01>AE7&8<0:G'E4:70?D3A:<82F!<?,7&1,C
@r5036
TGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGACTCAACAGGACAAAAATGCGCAGCAGCAGAGCGATACCGAAGCGTCACGGCNGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCA
+
47<*757;8=?>&#<&/6D=BFF!>8/(HA==!"007"D@+/A1!2@G%.$H7F3;1:-$!,$7D5?$#?9%,3.1,B674+*0B*+D%D72HC./:=#68H:?H<>AFD>#?+"2'>B?B>/>"A6'%"$8A=E";DBHG9:B9D8G4$49+0<,DCG2%(79G(1#/C$E:EE
@r5037
AGCGGTGATGCNGATANAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGT
+
D6&)5G6'3+H!A9-!;%>0.,<.:<4-H(*+%=.!C4&"C%02B&)AA&4C1(AB?2H@#
@r5038
GTCATAATTGATTATTTGACGTGGTNTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCAC
+
%35E0G20AA&F83F;8#42;-9G,+59#A=#1B-,F,8H0"@2:$,45;!!D:2BG#6*7529C1"+E'0@(2
@r5039
GGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTNGGTCTGGCCAAAGTCCATCCGTGGCTNCACGCC
+
#7'B*"7@BDA>.56:23<0>2!2#AH-D.-=''6::1E5!D?2>5(2C('71F>D<A'5'78D;#&7@,%;?/F/E+G0B)7,,G.)AG<B.(--1)+?29
@r5040
AAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGT
+
"$C"0=H-9HE#11+2H++/".1")$94H:(2!&&-9'68@E?'9@867F!-(.%.*"D32@E$&/F7>3=82DD-2
@r5041
NAGCGGGGTTTTGCTATCACGTTNTNAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATC
+
!<4E2"A6D1'=F/)5=A!8<,4>.&$A-%/#5<.F*$C466A.*-H(=);%@#GCH5D/69-8C/$-?78B7D>6<
@r5042
TNGACNAANGGNGTNNNGNTTGGCNTGNTTTNNCNATANCNNAGNNNGCNTTNCNGGNNGNCTNNCGNNTTTGCAATNNNANNNNNCNNTCNNNNCCANNTGCNAANCNCNNNNCGNNNTANANGTGTNTCANTTANGNNGGNTACNNGTTNNNCNNNNCAG
+
#$!$#$"$"$""$!$#!"#$#"#""$#"$"###!#$$#!!""$"!$#"####$!#$""$!"!"!"!$!#"##"$$#!!!##$!!"!$#!#!##!"#$!""$"$$$!$#"!!#"""$!$!"""$!$$$"!"$#!##!"$"##$#$$"!""!"#!!!!##!#!"
@r5043
GGTNANGCTGNGNGNNTTTNAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCCCATGTGCACCGGCACTCNCGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATA
+
))*%%!**(*%("&*"&!%%%+'%%($*'%!)*!"(%+)*+&+#(%"&&'#*)'$'"'%&+"&"*$+#"#)&&*#&(+"+&+!)%*!+&##'%"))*((*)!"%+'&$""("!%#*)+&'$*'%#!*)'##)$+!)#'#'()*#(+#('$"#%)+$#%#'!%#"'!++"')$'+%+#&*"$%"!%+$$#")!)+'&#""!&)!''+((%
@r5044
GGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCG
+
B*<:E>;'9F;&GB@,*D*F1=1C"'<!G924C<9>39+/3G:E#E@?7;DH*/87=(+.,/
@r5045
AGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTAGAGTGCAGGTATACA
+
*9FG<#<7G75%CCE45E./B-8&?#'4!G@0"B#32.2.:GB<3"C+47H><))HB#$)+?.%7!A
@r5046
CATGGCTCGATTGGCGCGCCAAGTTGCNGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATC
+
<HE%5@"2292?:9,<D,A''1FH088"&@4808<'<&/&:;<*B$#*E3%H6;EE=0-1(BB=H5A<.$3E#!4'=0C1!+->(@%C<1DAF9=CF#H/$G)HE-?:.2*3.F0E
@r5047
CAGTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTC
+
9,@B"(.5=#3:F8?"H-B!+?/)8-%/+;E8#!*;EF,A<)",:D5G5"EA%;+39'
@r5048
CGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCNGATTTTTTGCGTTGATT
+
?7D64$,*@/B.=G/(C85(&C6A?;C26G-"2%+E:?C!*,==483?.>E##!%A&6"A76"?H@5"=!%9:2#4.&?E*#A<+*H%4$A#"1+@4C82AF7#294
@r5049
TTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGTGACACCATNGATTCCAGTAAGGTTGATTTGATCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATG
+
%8,1;;5@$H2.A@?B1657C=::A<<>$(/4+F(0%4=84?45E1-#4(%.'=2G-GA2F/=+5+BHG-*)3+$%31+2C6=B#*>?4+'B-3.*0<*B#+H0H6/-#D&<*;82&+6:6C3++#4">'>A5!6618.+!/&*&6/.;64F!104?FC>3E70'E-$,H#3!88('C)/+>
@r5050
CAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGC
+
3/#-D<0<!,.@D7H>@757=%''%9&%=6?,?)1>;D4G$D!(HC+.8<--+2F5E&',$0E*6D=(:-'-==5860H#A74=HH,C!/!7-5<43G"1"%G($D!>A4;>7A,
@r5051
GCTGGATCTCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCANCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTACATG
+
<2G+#3:;/&&F<$.(>H>+G-<G)"9192E1DA56!"9&?<**)6/20E>9"4.06G%!+;H?D>H/-B2,&GE=19%,864E117*<6*DG<"84A.D'23('EA<#?2)".*;6AG#.+$H0(&4D.,C$?27!5H8HB)C'/1B-DA
@r5052
TTGTACTTTACCTTCATCTCTGTTNATTATCATCGCTTTTAANACGGTTCGACCTTCTAATCCTATCTGACCATTATAATNTTTTAGAATGG
+
&@%/'@>1AG*34+#B576=)BH>DH-=D'0*!!?#4%0:9+#,4*5.4F:3:#!*6FA1H2>/D"E0<.C,G3=>')(-8.'7)=&<<<8*
@r5053
CGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATG
+
92)*;B7=%'C7?G'>('$)D8&$,E--BA$7?$"(((4.:88!5(B=:>-DC)*1)D7%
@r5054
AGATAACACATCGAATACGTTGTCCTGCNGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAA
+
H=8EB?+!/=70G@138?45)?@3;*"?*-FA"0+<'5@.!1=:,/69$)+>64?>&%$4?-->/4?<7:!H=3A2F65F5$3?8G-!;H=9
@r5055
CTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGCCAGATCGGATGTGGTCGGCCCGAAAA
+
27",/@>=D&,".B1D@*A((+1,&>;/CC5/*=0"7.ED"80%#@);A!9&)47.1A'&B9+E!A='F.C
@r5056
NCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTNCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAAT
+
"42)1..F')/$,D,:3A9*&4!?,A7:3!B+<&B<)!C<>:@5C7((B#-'$2!7!;1**A/=,/8BA-)*;=2@6#F86?G<E9C=F(C1@+=)F9/=A,H:E%.:913*)#2:D&=,F61.G*"H:$7472F+=)-B>(!C&-+&:@":(##CGC3D=-9,4E?.?)+;G9B"G$9&8D%!#"(0D6=C>C8H!613A#;F"/%:G*E#/+A;?,H7+G0F0:A*50-E75$!'--;7$+#,DC'.2)'D-86:/8:9%!.FH+)"><A3=C.B>/>4F7D4)*C%8!!;H9A5<%31B&1$0(0'+"!=E2.E&C$8DEC8
@r5057
TCCTTGTCATAGATACCAGCAAATCCGAAGGCNAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGG
+
40DC:H/.0&FE07BA#2;02=>=D;B8"F@#=?DD3471(%/D/BD:5*-C-7H#8D&?*-'"-+!-FC.+8A"58G0
@r5058
TCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACATAGTTAATCCGGGATTACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAGT
+
A*!5G?"?>#C;$=:!:3;$7"C+>@=C0:/=+072;D,0D0$8?10+/,EABDCH7<5,'"@F5C9#,7-';,H0!3"")?)!($923%#$8+"E,:.
@r5059
NAACCATATAGTAAATTAGNTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTG
+
%-73;6-1B?%AA/,)"%C1E$B#:&'F+H9A>*!#"??,FG)D,+#DC=0E9(H-C'%2B;<58%/=;B55:G=GG9
@r5060
CTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAAC
+
,@<52F.,5+B'28!/D@3>&53H:=,<)*6.E(<6'-B#$@2+*#@*-":(9BH/46EH144!G-**4+"/'BGFC1G@@(#G2(3$0D)5D?#/C
@r5061
AATGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATG
+
=E5"HH&!:17GA"0)D.F*$<)9$7>$C1:+H1A,C>'F.+CF.#G&6:1;H99>)+&$-!,%40:@A2/7@F"&@&//F>A:!@A('74&:#0,1B:3A->0")-?)>;F%%0G2#2=3=#):D$BB-AD/'.3>4F,0<:&3.5"<!10-=@8+=7FEF('(8?2HB,4
@r5062
TNANTAGTANNCAAATGGATCCACTCGTTATTCTCGGACGAGTNTTCAGTAATGAACCTCTGGAGAGNACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGNATATGTTA
+
'#('!*)!&#(#++(("*)!'#$($*)$++()!("%!*$&(#&+*&!))%$'(!*#+#*&$+##*'(&)&#!*%)"!%!'*(#("$!#$)*(&%))$#)(!!+")%'!$("%)$'*#)')(%)&%$($$&!*#(&$+'
@r5063
CTNNCCATTNGGCTGTCCAAGCNCCGGGTTGATATCAACCTGCAATACGGTGAG
+
"&(#++)!"(+*)!*%$*"(+!!!!&+%'*&'$$'%)$$!%!#+('!%"")"$$
@r5064
NTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTNCCGAATTTTTTGCACGTATTGC
+
$8;0-5(2>F191A3)73(68;C&F-8-4;+!!)A(CG-E#G+(BE1>5:)>6'-='+7,?!-*(C%%,=9;78
@r5065
TACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGATGACACTATGCCTGTACCAAATCCTACAATGCTGGTGAAAGGTGCCGGGACCACC
+
0B51A*5;(@,A1!"@!;HE//=$/77%3H.7.22*=9$-9'5B&4+H),4B#C7;.C-G"?-A$>'E?/;':,-E2:),EC@B625./%C"&3??#BFE4;$35@+1'+"B65?1=,?02'<#@*"
@r5066
NGTGTCCCNGTTNGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCNGGATNTCGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGATCCGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTA
+
!'#&'*&*!'*'$%+%#!%(*+!&"%$%($*$)$#$&&))#$)"'!!&!("&!)&"""'!($#!$!'"$&+%*#$)$!*(!%'))((%(+!*!$%"(&)*#&"!+%!**&'#%%+(&"'+"#(%)"%$*!#)+*#(!&%)+#'(!&%%)&$'"')%$"'&)%+(!"+$+++!#$%'((%"!**'"+('%+'%'")+%!!'%)""&(#+(''(&&)%$$
@r5067
GGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCAT
+
'?952#/1>/)/D%H,-4+7".2.?:H30<<<55E#B89?<6'<#D8@-(A<-,F.;G&H:81B24F/&*5C$2=5#&D3"?/G-,<G2C>H<5)%@3:A9DG%426)>CC%8$(
@r5068
NNTGAAAACCAGCAGTTTGATGGCATGGANTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCNTGGCAGTCGC
+
!$$'+&$%*'&!(*!$%''$*!!'*"%#$**!#&)%$+!("$+*$%"$&)##&(!$'&($(#*(#)%(!%#!*+(+)+*$&$#"&#"+**$"%$+#!)'$($+'$*"#()%)("%%!#()$+#''&'!+($)%$%'%+"'&#)#%&#"(+(#")%++('%%!%+&!$'%&''(++%"&
@r5069
ACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGA
+
5G$87BF4&F4:8!4)$H0?F>9".1>)0$7%;10E#&:(G-D0#@G1(.6*>F'GHB6+?0;F0%A882D):E)C&
@r5070
CGTTCGCCGNGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATNGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGA
+
,E01$&<6+)2?D<%HH(AF!##+""F%4=/CCB>>:>."D>70.<A6E*&4$E1-<@&AE)2*E330=#-0?E(G4<1+>?:3(+&'%.4=!?5/.6&7)/>!#(*9B8'F6(.!><<9*:H>&58?=-""%85DH,96+,(
@r5071
TGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATA
+
34/!C;./1BC-*C"(?&4CFAFE"#(;<G)GB84$@GFD'%251B%:8=C)7$A9'$"-;C8='C#CA.(G.*!F4"><)--<*$444"?%B!@%(B/?@E/9G48C;+
@r5072
TGGTANCNNGGGNNNNCNCNGCNANNCCGNCNNTCGTNNAT
+
!$#$#""#!##"!!!!"!$#"$##""!!#!""#!"#!!"##
@r5073
NGGAGTGCTGGANNGNNNTAGTACTGNTACCGCGCAGGAGATGCTGATTAANGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGAAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAANGCCCGTCTTGCGCTTGAAGCCGCCCGAATGAAGGCTGAGCAG
+
"''#&*'$'$%!'!))%!*")'(+$!*(*#)#(")+"+#$(!'&%&$'('#"(*#$(&#'%#!*$"*)"!#$)+%&&)##)+)'%%(++*&%%$%)%$!!)!%&!*%&((++*!#+(#)'+*#'(&&+()')'+"#)(!()*&$(#("($")('*&%&%+*())+#$"#"(%$"')*+$&!(%($&+"!#%##!&)'
@r5074
AAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAANA
+
$F*ABF4#-5FH89(0G/F1C-':0123=?BC&G&@A10*F-8"11%=56=E3200D?$+EB)1.592GA$B5"!E4*=34
@r5075
ANCCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTCTAACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGNGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTANCGGTTTTCCTGTGCCGT
+
*$(&%)#%#)!#$+%&(((%%%('#++"+(%!#&!#%*)**()()#(!#&%*+"'""*!*%*%'$$*"+$'+'&!))+"#$*%&$$%&%+'*$$')&("%*+!"(*&'!+&+('&%%##%"+&+*)+'%&"*(*(')"+#($+$&+"$!$%!*+&%))"!$
@r5076
AGNNCGAACTTAAATATGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAGTCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCT
+
!%&"'&+!*"%*"!+)#&'('%$+&%&+)#&))"***&$!$)%"!$!*)"!'*+($%*"#'+%&&$)(("!#+'&+(%)"$+'&)#!&&$"&"+'+%"'$*)$%&&+&$#""$)%$($!$!)+)(##!(***$#()"#&)*"(%+#$#'$%'+)"+$('(('+'&('*%#+"
@r5077
GCCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCNCCTGCACNCCGACCAGTGCCGTGNTCNGGTAGCACTGTTTCACATCGATGATTTCAGTGT
+
*D@/=2"H2)$B613619##*:(#=BA2,#B?>$E37/++=??-*:$+/55$7-(1E%F$2G5(./<6-B:0F5>B'?DE3777A,91'9A/B/#,4;D%&29'7',!AG3"!3*G;-#'E&8$06';1B
@r5078
TTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGNTGCAGAAATTACCGTCACCACCAGTTAATCCGGAGAGTCAGCGA
+
6=G8B2<"<B09E>9,8B55"C-!A?>1?'=:@$80$".<BF+6$#")%C+"F.;1,G0D?-C$"?(9#((B/(-58:@A6.=F7A@&:C32G(<@/C;D94
@r5079
NATCTCAGTGCGCTGCTGGCGNGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACAC
+
!$C.,?H$)<!6B)0"G11.@F8E6F8'!&=093AHE)*$*?=@88C07%-A/'ABH0E8.1D:
@r5080
AAGTCNAGANNNCTNNGGNNNCNNTTNNCTTANGNGNGNTNNNNAG
+
"""$!$!$!#!!"!!"$#$!"$$"$"#"!$!#"$#"#!"$!!$!#$
@r5081
CAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGA
+
/E$7E>'3/">.)1C@<52<4<08&-2F%?'"<9D%65)G(E=E>B)1$5=1))4FC8;7AFBE"@GH1-1"ED*!&<<084=97.'.=3"?"+!4=HF<&<C>$#+(&3/%E6.;(H0CA'4(+=E'#"A2/F/
@r5082
ATCACCGACATAATCTGCGAAAACTGCAAATACCTTCCAACGAAACGCACCAGAAATAAACCCAAGCCAATNCCAAAAGAATCTGACGTAAAAACCT
+
AH?:7-6D>D/.E;251HB;+?C4CFD?'7.8&AH,B!E&H)B2?"<;!B&2#7B0>E(A??:8>7#7'-H47?$@G?,FF:*61FG-1G)!)=C5-
@r5083
ACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATATTGTTCCCAGAGTCGC
+
81!H<8*$'%,283)?<4E(1.?E9%8=&-2G0!$=*A0G2"1:3(A03?2GH)/;D*A,%3
@r5084
CCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCANGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCCATAT
+
9$!(3+F;00G#!&?28!+<$6?#3*22BC5%4*C>9,:2,B"E777+*HAC0'G3:%+9C#CFH!3E8B9EAA(:EE-C&642/5.:0:.11?/!6+*D@4)E472#"/5#H.5E'!8A=C,3"6&/77:'=D2,5
@r5085
NGGGCNGTNNNNTGGTCCGGCGTAAGGTTTACGCCCGTTTNCTGGATGCGGTGAACTTC
+
#!'$'#)!"%%")+!*++#%()#(&'*!"*%%#&'($"$)+(+*+("&!'%%''$$&($
@r5086
CTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTT
+
5E4,+-8"A0&3*68!#G36H#B<9/"3:/@);$5("6/57)4"
@r5087
GAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTC
+
0<3B2>$EC,:;(")&B:?!.B3<A5!0DEA5!<)!"2.&)@(&"BBG#%./?/==4/E&65@>3@*A%,!@#??)A8"25#=#!9)*4D41.6')-AH$#67?%EA!"A.B3/D(4=(>5@8E&CC/$'A@?$6).D-F9*6%8G49D(6(1864F#"-216E.C"-"=6-"#E??E:?7
@r5088
AGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATAT
+
(4E%8/-H86=9A')32@!D9#&+3#8**=F#(;@A+=0(+$A(8B-F::"5@#*51!*6/:*!=;.@,1%,;1/9,(C@A#<;1436502A5<A/6D5,*8?3$!.'7AB-9G?5EF;00-'1%<H!)G
@r5089
CCNNCGTGTTGTCCGCCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCCGGAATACACG
+
%"&"+()"#)&!()"#'()#$&(+!!')"!%*)'%$!'!%&'''##!$!#*++%)*"%"%%$*+)
@r5090
TTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTGTTC
+
.#$2+/35@5#94/3-FDH2D!@DG?#"$E.G?/$(14*1G05B7C1%!0
@r5091
ATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTAAACCACCCGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCAC
+
=)==;14G6"*)?;)9+6*:39</?.A,9%&2+A%+2)95"C:=GF;=%,?CHH.2"B#C135!,'CBF"6'9:B6:4.,7216A!4D:E*A-9<+"01),/47'A*6#8%2%=*'3)$'">)(,C-8(=F1D9,+'74*@#"D@%1G/G(BH@F1C+;*,3)3,B3H<DF7E4(+>D=5E2(288@H>;:#%)$-3C=A%*."3>.%%%1$4!,#$'(#.'<'6!F
@r5092
ATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTAATNAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCT
+
"FBE+7?4'!CG-))$E<!.;2<0B=7!1/2#-4">6+GG"@>C$/3=2&C5A4/E;@22$!,<69!%20F,>+><:-B)6*2$3D#E")!/>#+?<:-*$2=G,55F,4<+1?!@<C#+/ABH2&?E#"-)F+#G#,"=<-&-@>!?
@r5093
TCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCANACCACGCTAATGCC
+
H8-%5%&/(!1.9!'FC54"7E1EF>F'0484EC>"14>#.1,77=E>#CE7&8,,0.8'-.!95A'+,
@r5094
TCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAAT
+
1=2B777D@@A87<=,:2$/%6'+-?-8@C&.B5A>:C'6E&
@r5095
AATGACCATCTNCATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGG
+
%0(1*9G4DDF.8/2.H??A/6=%@#C%3&F-6H0'$!C#4*85=/8D5-88'?BD';%"F'&>
@r5096
GGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGA
+
?915@:@.&$"E)F78!%8H+.&*.#EF$&"@F*$)'G2-0#H%'":0<3&/74(!*+8E;).<D
@r5097
NNCGGTTAACTTTTATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTNCCAGTTTCC
+
""D*$C+/61A9&0)9;$8,C=-7G60&'''>/#&:71B?2554,&'%F4("+#3G'?":'@<7/=.*!C('+8%&;!
@r5098
AGNTNNCNANCAATGGTCNGGNCNNANCNTANNANNGNANNGNNNGAANCATGNCTC
+
#!!#"!$"$!#$"#$#$!!##!$"!!"#$!#"#$"!"$$##$$$!!$$##!!$#"#$
@r5099
CTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGA
+
.(@1#4@)9)).77#)59=&<C'.672/EC6&FF2<G;B@EC;:3'*)H$=*=A455H2%"#/B!(..E;&H(@!$(2/$+59.?C$&4@D)G*0.,B2
@r5100
GNTGNGANTATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTT
+
(%'$''$!(+&''#!+(#!*%%&#%')*!()'&"#&%"*%+'%*"%*(
@r5101
NGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCCTGATGCGATGTTATCGGTGCGGTGAATGCAAAGAAGATAACCGNTTCC
+
$D'E7(E#2,5<937="8$+#-<-F#6H5D2-CA=/?<C%?GC7%$8!6:/&8*174DF+B#:8#!B*<=5HD+?/54$C9B<2*:,4
@r5102
GCCGCAGAGCATAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGT
+
B006GH&#>7$,9)"##(?2$./AA@)/@+HA@$91(.$'(%></$?G87
@r5103
GTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCT
+
CG$@)6?'5+-&&;H+7"HDE,5!1$$>@0&B4:G1#&"AHD=A=D!C."D?#)C)F6@/GBC:28"D8/-F+="H-&=/9)*.B>9.C+,-1?.'HB)91(<1$GA?.0:F
@r5104
CTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGNCCCGC
+
*72A9/,#+(''$1B+@,=-EB"79/!-);?",&*.2./0+B2(87
@r5105
CAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCAT
+
+($&)'+#!$+"#&()#'"**)#'%!!&!$+$')'*&(*+)%*#!($'!$*"%&"#%()*+&#"'')%!*'$)*+"))++!&#'*+
@r5106
TGAGGATGGTAATAAAGCGATGAAACATACTGANCTCCGTGCAGCCGTACTGGAT
+
674*&F)*EA/=<%%555:-C-&12';(!&,?G<E2F'B>49%1>H/(>*>:&F/
@r5107
TCTGATTTCGGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTG
+
>95"$H1&D;>>;#)7>7*.#?-B"+<)A5"5<626-2:9B,/592EA9%/>'0?;9(D%(4<->B0!"D(E4970C!5027C"04$-,?4%2FF*<C(B6>;0E#4HH%>5&::
@r5108
NTAATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGT
+
&(.$0B6C2/<<B8:8-E(E-)11#".F))@/(FD3A00,&'.&+*52.2C#?=5#:@"$3!EH)FC3'*A<0'BH58?4!#6%+":;%":F*BH&B5%'E7.!9")4;#AC2C;/#/:C)-8"=*-?"11/0!C=D$$)D6.+;$:&C.2B>?&A?.E;5!35F16'>'.-$*4*'5(3A)%E$?#%.;?6!0;@=E&18DA;)%!10C:1..#",4
@r5109
CTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCA
+
-89#2D%1-;&,+.=9?!)<6>("296!$;?0FEAC"#D&!1D+-7'+1/@%=C%-0=$5?/?H%3.<&
@r5110
GCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACG
+
9-8.?*2?##&0$(3(%AB:"96(?B'),;G;")#=31H')1)C?!..+1BA34$<+>0B!<C-D:''!+CC%+GAG-9.;.AB4CH$?4C>H-?=53%<?:E
@r5111
CTGTTTACCAAGTTCTCTGGCAATCATTGCCGNCGTTCGTATNGCCCATTNATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCA
+
D)AH1.!1+(:&!B$'8+5BG,&@>,9>):>E??)!$H?F98?8!(!1$#HF6C0-@B2#'-%*@'2*-*&$7-/!)<G&.!+,<@-8:'//B-
@r5112
CGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTAT
+
H5#H#A)@0!)@5(B&?;.G1E)<A1B;+%G?14=3*@!8$&)@EHB4%)GB64@<45
@r5113
ANGCCGANTTNNATNNCNNAGNTGAAGCAACGCTGTTAATAGCCATTGCGGC
+
((')%))"##)!&'#((#!)#$+&!++'&*$('''&($)!+)+(+&(#!*$*
@r5114
CCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTNGCTGTCCAAGCTCCGGGTTGATACCAACCTGCAATACGGTGAGCGGTATATCCC
+
8+&=6:H/F'$<5>HE3>E,AB42$#&<C5'2#-6*@?,4%8.CA*/;#3AAB6E(H"@,>4*'D2;GE$.&:46,)-G4G.5DG)FC3C,'D6,0FHA12H-;.83<6G&1E;*9>1;?#>?C=*34"1"8D%9CF32A:/
@r5115
ACNANNNTGCAGNCCTGACGTTTCTAATCGGAAGNAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACAT
+
"(#&(#%*'&"#$&$+$%#!!#"!!**!&$'"&$'%(''"!!+*+(''$($+"'"##&(*'!($*("&"+")*!&(#"$($
@r5116
ACCTCNTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTT
+
24G+H*-498#".CB$BF.%:&<?!4?(8/!.<FB;.*2?/DAC7.4
@r5117
GAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGT
+
@%9(@48"H61H9?/+(:'7F26+"(G?D6.60D.!*+'<800/1"$,124$!&H1C#GAG
@r5118
ACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTC
+
F*'0!0-$2/G3+,"#'E;241A&)8<21;$$1H429)D6#@+-?H-/!
@r5119
NNCNANCTCGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAG
+
%#&"+$(!$"$"#(#!#+'#"""'$&$*(+$#%#%"#'"!%"*%&%
@r5120
CAGGCCACTAAATATCAGGTGCTGTTGATGTATCAACACGGTTC
+
H;B%/:'6*"+6D4').,!"D)*$=H3H@'AH+G??A>=9#8D#
@r5121
ATGNAGATAACCAGAGCGGAGATANTCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTNCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCA
+
:&&H?*G<436*A7-*6?,?>.H-:11C>83#9-!C%6;0G08<<)B!.25''8#"H7(#/'4@D:D+7::3:A/35B5-GGB5/<<3H*:8H);.F"&6)
@r5122
ATGCCGGTATGGAACGNGCAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGA
+
2CF2)-&F2:6A#**GG>#3D%*4G5H##$%%44!7?"?=6G)+?2"-$7:E67400EE;B;G47>'9!9**;4.D86D-#/:*5%>;
@r5123
AAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAACAGNCTC
+
9>F0B0'"/<$0*%7,"+450?E@;<#,A=HBB*;=-:"!9H61;:0E*"#&@%04#F!FC?H
@r5124
GACTGAACGNATNAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCNAAAG
+
+C:+*!GCF3+5?<#%::/!4DA&,#,7*93'@%(<,E%798C;8ED@G@B--&,4E<CA+?
@r5125
NCCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGNGTGGAGCAAGCGTGACAAGTCCACGNATGACCCGACCGACGATATCGAAGCCTACGCGCTGAAC
+
'*+$!$$+$"+!#'&"%(*#!&*$'%+!&!*&("!&(*%")()!(*&%"!&$'&)'*&"'#)$!+!(!+#%)%%!"$($)%%$"*#%!$#*$"&!+#'%!&(%&""&*$$("'''!##*"%+)'+"'")"%&!'!&&+(!$((&
@r5126
ANTCANNGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCA
+
(!")&!'*(+++($)&))(#($"((*$+!#)*#&&+!)%*%''!(+"'+#&'((($*'%!!"')'%)&"*)$"")&!!%'('!%#)%)%+*($*+$*&(("(""#++%
@r5127
GCAGCTGGTCTGTGGTGCTGTCCGGCGTCANCCTGCGCATCCGGATATTAAACGGGCGCGGCGGNAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCT
+
=9.(DGF00/G20CCF=1BD"=E.&D0CG+.0>"#.45?-++HD,&D8;%@&'H:B013@0-+D-,0.6EH!>,3)00,.44>=09'#-97:/*BBC"B8F+)-$A&+431$'(
@r5128
AGCGCACTGGTTAAGGTGGGGGTAAGCGGTGAGGCTCAGACTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAG
+
D-G"&1E-2.92+A-.$$G0E$00@54G&26G2&FF!D0';7F0#.!D762G/#;(5*/=$468G;58,=>-<69!$$(0@$D#.#!2<533E4(D<G'.!1H<4F+<;0=3CF,8H4+;:=482!':*,"/F
@r5129
CAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACTGCTA
+
H:<-*,,?C'@F8A4H#+;>/./C=94#BA6H==H.%A>;.8(@HH17*7>,F=F$#G!:;.&&==E&,G=,H8-C
@r5130
CACTATTTAAGGTGATATATGGAAGAAGAGTTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACGATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGNTTCCTGTGATGGAAGA
+
7;*#682<A4+#A1G:1B>$B:@2049+H@A!*+H*%-?$.*<D%2DB+;)BEF+3G1!/.=$>+8AD#-$/",;-)F-/A9(72BB@77#9D1FH*#?=*>>(&+()%3,>=B%7A5:)'4,08E1(8!1.H5-$;#7"HC0/F?!1(E?5#H&&90&5>'70+$88-1H0<(5E3"(";DC416"495'>4*+':!A;<89#
@r5131
CTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGT
+
*#19E!%'"HG-::9)BG51*97#=###4*5:+=G;)D73C$D4E$"387C2F-A=@F%B.C8,.H."
@r5132
GCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCNGAACACCTATTTCTCCTCACTGGA
+
/B6H(&"1:)(F@B?@1)%96>,A=>1&CD0762<A38+D9F/:-+A9@/&25-E)D'>4-0C4D?8>"+27H+
@r5133
AACNNATNACAACGTGCGTGGAGGCCATCAAACCACGTCAAATANTCAATTNTGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACCTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCNCATGTCAACGAAGAACAGAA
+
(()!#&%"+()*()*'"'%))'!($"+'(+())))$%'!#&!%($(!$%!$"&()))''"&$($$$($")+"%)"!$($!!($")"!()""&#'"*'&'#'"*%$(')((!#*!#+++'"#(%"&)$*)(($(&'!&'"""#%&$+*)!(*))*"!+(&'***)$
@r5134
TGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTNGACGGTGCTGCCGGTGCGGCAATCCG
+
$4=126,(&#<-14'%!&9%FEB$F>$HG">31.C!6GF6(FHF;E"*;8%4H2BC;)2$D'C7,&
@r5135
CCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCAT
+
C.BC$6G*,C9>**/(6@G&7%D*E4H6*G'G+BBGFF':5*F/?,*F:9.6AHF#%/B22/GCE2G$/,B6%*4"*/>7#=
@r5136
GTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATG
+
F-&5,4+7#&E;/>@%"-H;19#+HH'1'/9DEH#878'"
@r5137
CGTGTCTCAACGCCGCAGCTGCCGCACCTCATCAGTCCGGACA
+
861*,0(%(E/)B.E8C*@('&1%$5:<A8.E/%.#$81>28E
@r5138
AATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTNTNCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAA
+
+=!='F*G&.G"G*@*!H;'C8@;(+,2D$G2/#DH+*>D2:7@2/"4;%E6(21C80B>(3=F-)--F/..1!35HA/-)
@r5139
TCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTNCCTACAAA
+
=E(D5;2-=F/>;(?!#<%<7C/5'?=3%73'1;ED;.&3?+?;3<9$(37'H
@r5140
GGCNTACGNTATCCGCCTGATGCGTGNACGTGACGGACGTAACCACCGCGACATGTNTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTNANGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGG
+
$#%!&%')*))+!%*$&&!%**)*"''&"&&%''#*+')%'%'+*+#+$$%%"$#'(%(($!))('!(#%)'#()(&%*!!#&"$$"#(&')'*&'!"#'&"**)"&#$&##(+"'%+*%"+")##+('%'(!&%'
@r5141
GGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGG
+
67E/"4H"0=2>52%1"(A).&56(?!9;,;8BH?38),"1,$BC*1,3F/8@)6*?:':6=+56@:%E$6G
@r5142
NACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGA
+
&1HD',387G8+<!H7(D*GFH?9?!5$2'6A)B9(9("@5?9F:>'0977&$H?89(H
@r5143
GGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGT
+
=5<44A2774"+%.!0=4>3/7F59);81!>A'952:/778,!
@r5144
NCGTTNACCTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGA
+
$*)$'&"+$#('(&##&)%'&#&'%+*!&%))#'(#(*#)%$$(+)(%#!!*!%&'#!"((&)'%%%(!#!&#'*(
@r5145
ATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACG
+
=7.1C*/!F.$63&716"<,"8,8E@'3=,,?)0A%>2:@/#A="#='=H-D!F2@$)6-F-BAC:56<1A/>>.C99>)9<:@EH-/'#D5GF@@;H=:B#&?&=7#HA6&
@r5146
AGNCACCGGATCTGCACATCATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACTCATTTANAAACTCCTT
+
"(!"))+!)%'$'&#$#**'&#")'+"$"*&'+&$(&*##$+!$$"&$+''$#''!()"*!%"&)(#!))(+##)!)!#)!'$
@r5147
TAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTGACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATG
+
*DB?<.D5D/88G&-,5;-9)5%%6667=92?'*8E&95?,?6*<-<'-2"8@87'4:6/<+!,/)H3F9?3224&3;10?2?D$)A%:<"@C'!))G9
@r5148
GCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGG
+
<9G@9:,77,&6D-.!$-F:;,6342=5921.>G%8G&BG&:1%;?</B'%)9D62@B9-9'2':5+4D-1!1/?%D#F'8C9B.;/:+)C/>E%0/+<(,0&$*.'-,:=$*
@r5149
ATGATGCGTGACACAAATTACGGCTCGCCGTCATCACCGCTNCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGG
+
5>%7D*,*>&F0'HC>>#>E+.E"%DH-DG):&!33#6'-E-2#.<?%3@.;!8#D%)C48?-/09%G%E43#)*2=>/-,+6*:;/E%
@r5150
CNANGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCNTTGGCC
+
!!(+)'(+#")(+(#$'+$(!+$)#$("(+&)$%'*)")"("!*""%#&!&("+)++'#&"+%"&#+!"#'*'%*%&#!&(%%'!''
@r5151
ACTGNAGNNNNNNCCNNTCTATNNGCTANNANNANNTAGGTCTNCNNNTNGNNNNNGCNNTTAANNNTTCNNNANTAATC
+
###$!$!$"!!#""!"##!$#"""##$$!$##"##"#$$"!#$##""!$!!""$$!###!#$!$!!!"""$#!$#$"#""
@r5152
ACTTCCGATAAGCGTCGTAATTTTCTATNTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGACTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCT
+
;%#&9HCC(@16>(5FBC0(?'<G9,"B+@:7H'/'"%-8*3+!!8H+0&'64#6F1@?==';/!&.DF263$$.G71;.!?C2'36;!!>22/A:%:**EAA@-=-$)54G07$)4+E,AH4?=8
@r5153
TTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTT
+
;)A)8!9GCD9*4AB40$*HBG1B=D0$@;=*=G')G!7C5A=8$$<A0>42?9EH0..HHA),F)4-@!%C/%:C0+#?5750E#*'(,#&('#30C:D"7>!-?#DF<<%*H(G0%4%&5*A48?-;8<B#<
@r5154
GNCCGGCTGGAGTGAGTGGGAAGAGAGCGCNACGGACAGTATGTCGCAGGTAAAAAGTGCNGCCACGCAGACCTTTGATGGTAT
+
E!2B5.??3A?&#F32/(&**;0;2=DC.6D7AG4?%A=8/34@HA%&<!+')C-268$1($2@E%1!D+FA&/4<F2"AC)F'
@r5155
GCCACCATTACATCCGGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAANATNTNAGCTATG
+
094A:BBCE/%C;;;##!#=$('5)19/F2!+,>G8.96(:4<.D/8(-;H>?1F0<AFD)G,!=.C'"2<3D&<F
@r5156
CCNGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTGTTTCTTGAGAATTTAACATTNACAACCTTTTTAAGTCCTTTTATTAACACGGTGT
+
/%AC/C53B/45B?E#-<3.?5*9&$).$?9D@'>.E&*&D0>0:53>>.$,6*E1>*F7/;@>763!,#(AA77'(,5.*/+-1$2::"C?AD48@50!?A#.<3#(0E"2A,C%G%/0<'$4>?'%>$!==?DC#!8=@B
@r5157
GGTCACTGTTGCCCTGCGGCTGGTAATGGGTAAAGGTTTCTTTGC
+
*@7<5D--11(-65//;G8<:"G?0(?7-"=B<?BA61,B&/?46
@r5158
CCGGATCATTCTTTACCGCCGGAGCCACCNTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGAGGTGTGGCGCAGATGCTGGCACCGAAANC
+
7=)=B/)C2?7.$45D2=:=4<-;7@#EF#!#H;<+@D1>6$CE/DD80=B4('AE#$=HC*+8+B$G1:B$H*E/7G(G,85A6B*D2)2<H@B830C$(-E*!(#!AB#@0:B!>?G/<*D!/),"@2%#:BB&H7@
@r5159
AAGACATCACCACAAANGAAATTGCGGCAATGCTCAATGGATACATAGACGA
+
:=,4(4(E&*>/<>>5F:D%H38&G0'3@/C<3DE+3(!B3$/?,105("H"
@r5160
GAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCNCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGT
+
56;+@3HHA676'-E+*:*)<"FE.1+7,(/@8$C?7&<<#;<=3"$A*+C"70'.BB*(53G*<=&<,E"6CF%,G*$53:@"H'F/8D"%A/=*HG$(7*BB
@r5161
CGACGTTTTTTGATNGTCGCCCNGCTGTTTTTGATGNGGCGGATTTTCCGGCNGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCACGCGGAGCTGCATATCGAAGTTTTCCTGCC
+
1+;3FE13&4!%#$G/.!F4#?D+-&C99F6EF0(BE803=$:A70E4#/%1H2H<05G(!&27'"1=$/?BA2!3;&./H@+F7+DHE>EC-@E,48G(:E+;!+*<8)4&3<*';;.<:F0>.G$&F*=&D75A-/54;G>.5
@r5162
AAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGTGCGTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTATCCACCATCGCACGCCGGGACCATCACCGTGTATGANGAT
+
2/6-5E%-9)!<''70%F=+FDB5+5:G32A50CG.8A)B8,=F<DH9HC6A6G+)<9#>C3;G>,#3/%',>(!3H'=H(1<+A)'AE:3;!#F*@!6?12"?70BB8>"2&)8E:>.G?13526%)'80'$/)377%*D(A69#2!==5$4-&"F.+1:>2E5D*=8'(6A'/>)D6D4+E'B'HD%.((2?%B6-)
@r5163
CTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTNTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTNTTATATCCCTTTTAAATTTTNGCNTAATGACTATATCCAATGAGTCAAA
+
DB)';#9-$HD,H!/4$9&B+1F22C9(<$C-=H#FA";6?2D57CD:%'2--C6=$:8.FG;.%2>82-3?,./F+"7,%0?%?@D35((;=*90'%$H7D2;1,)G?.)B>!0;4EE/6(/"3.1B*7$>H<H!G)C!C,H8##D82<&'79-9D(-#E@8B:1;)@60="#="-+;AE!D0C<&+C.763'7"7C6C1?(-F7;1
@r5164
ANNATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTANCAATCTCGCTTATATAACGAGCGTGT
+
%""+"&!))%"+%%&&$%'')"""(%*%'+&!%"*($')"'%'(&$&$*"("#!!%$!"!+'!$+!+%)#$%*%(%
@r5165
AAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGC
+
6@,B:C-3*:-A.F*=?42+9*$<<=!C@9E!4,%=4*5B.,1F'!5E%&,#%?(.$B,7!D:45HBC=*(D%->&G(CB:',$@H8'H
@r5166
ACGCAGTCGGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCANTTACTGCAATGCCCTCGTAATTAAGTGAATTTNCAATATCGTCCTGTTCGGA
+
&#D++91-"+/.!A'5)9##<C*B6!,-G,?B!6<%"!-;!(?=)B(,G>,-)?(>:H;%('$9!3,(*B>H&D8?!41H??8'7;,B'?HA.>2?
@r5167
GAATCACCGATTCTCAACTTAGCGAGATTACAAAGTTACCTGTCAAACG
+
0625=%-0))0+A-(140#0,622%9-.(-%=/=&&!)'0A@>!--..1
@r5168
ACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTANTCGATTTGGNCATACTACTAAATCCTGAATAG
+
::0(;E(D5?1?)->9!573:F0H/D.$*-".6%%-/+'9<;6/680@"E4D1E4*;2CA55'$8B+7610(".E'8>))F)02A3797,>4)2'=@,2=:-%H'"9*"D4
@r5169
AGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCA
+
B?HB:5E:H56BG8?,?$?&7';<#AD"(&GF*%7.-8@F)+-&@.G2#D.215(H!B1%!::2F6/'/C0,FGA/'D.B,?2:D("(3$,D;>$C.=?11BG71D=?,-6'2(-@<</5
@r5170
CCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAG
+
,(,=6;.!BH=EH1=3$/F.%(F>1F*C/)/3D7HBEC%?
@r5171
CACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGC
+
E8(:C1AF>4991?6@';/.8,..B8%0-;0-H-106',6#4+&C,-9,+:@)%5".0/7..1B*-F4CA?5,8%=$+(3'8CG
@r5172
CTGCACTGTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCNGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCNCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAG
+
7-(6?&=6?#9:*4H+/8G'<+.4:(B!!7)7(<,:(A.$6D%):6@E6AB(2B<9@%G*54B4&'.92B+A.(D:<.;)9.B5#*(F1*H:8';1++E-20)F9!C=6A+1.7>C=7)!H$,*+-=++=;D6-(B9BH:99B!C-9$($("%@9+?#<'*++E1.,;21G9(G94%G>34!<"6$6(=6(%C<D7$0%B'G5,6);5$042=?)3.
@r5173
TGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCAGCGCCATCGGGATTTTCACCACATCAATGGGNTAACGGTTTTTCCCAGCCACNCGCTGCATGACATGCCACCG
+
)+()#$*$)$)&%*$'!#%*"'"$&*%""'$$%$)&*+#"$&+'+%&#$$!(%"%"&+(#'$+"!(&+%++'+%$)"$#+*()%(!$')')##!&&!*"'+*+')+')$$"%*'%''*%&(%(%*'&+&&'&"#&!%'!"!+!%(%(%!''%$!#&
@r5174
ANAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAG
+
E2AG<EBB4-@0@H=E%)&8(6&.-+#0EA+*>:,+,;F&!')=FFF+C09
@r5175
CTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGG
+
17*714D38%*A9<$1*5@F.<.()77G:=E6@9G"$6)H+C6AE>2-37!$5:>50
@r5176
CACGGGNGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTGTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATNCGTGGATGGAGTCCCGGANNTATCCGGTGATGAGCGATATCCCGGCACTGTCAGGTTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGACGATGCGGGCTTGTGGAGTTCAGCCGATCTGACNT
+
'?"9@#7&07C!2452@.:8>$?"DBF3&('E),1#A5(H2(CE06C?A.>C-1+6@B(B$E>14A+FG2$B!<A2>18#':<"7D;E#*+.CF@16/B=<&7@'2.%$3:968D?D5(#%BA,E:A&$.(E?182=?<!8)5!-%H/E1@9"9?A*$2<$CGE+7B'))*BB<,&AG.'C/:'#F,;&AD%AG#-;9-57!489DGE*C*G$B@-&*&C;3"C%D!*7-
@r5177
CGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGT
+
HG0@;<9/%+<<C*2.,'C;D2:F>>(98&)11AF(18$27;CHF42E8>HE2/*4F)0;00A"8/+4FBFB+!'HG/7"D+,$C/?'$G'3%)EBF6-7#=99#57AH=*<<!=24-C0*$17&&,0F$>)%8>+#.!GB7*A!@$(/>1A'#;601A"#669F)=9;27A?5+'<<G(477"94+'%>??<;&*.:DH%"*+/'();.E822%G
@r5178
CNANNNCAGNCNNGANGANNGNACCCNNCCNGAGNNGCNNGGTCNNCCNGCNTTNNNGNTGGCAGCTNTCGTGCTTNNNTNGCNCNNGATGGCNANTANNNCTNNAGNNGCNANANGATNNCCCGAGNNTCCGACGNNNNCGNCCTNTCNGNGGTNCCGCNNNNNNGACGTATN
+
"!!#!""#!##!!"$""$!#$$"""!!"$!$#"$$"!#!!!$$$!$$#!$#""$"!$"!$#""$$""!$!##$#"$#"!$!###$!!"$$$#$!"!!#"!#$##$$#"##"##!!#!$$!""##""$#!#$$"$$"!"""#$"$!"$$#!!#!"!!"!#$!!$"!""##""##$
@r5179
CNCNGTAAGCNAAACAAAAACGTGGTTTACCTTACCGAAATCGGTACGGATTCCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTG
+
'$#"&('&"%&)"*+$)#$*%#&+&##!!'&&!&%(#+"#%%(&%!#%)*%&"#++*++"(##**%'#+"#%%$('#""%#"*!*%&#+!&*&+$!&'##$+#()!(&$#&##'*+(
@r5180
ACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTNCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTNTTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATT
+
GE#3,*D0<(D)61HHAE*"#!2/42E:*#%C3A;*$0;0:*6@C7(<51!*7$!&+'0+:3*%"':;!<#??+3@=9F"'/(28&1ED2#D'0G1.+=??@3G;2<B3,&!2A=F0#@E%692H8=$1%<(+:!)0)6H5$80.DG%=F>H'EG=/1E.>F2:B&+6"+<G#@;+->E&)(?+.#F!1+C<%F)+6"F'A8!$2??20AFG)$H<EE%G:.*%/+5,G,(-:*#(43B=6(:%(.7>,'&(F82D.4,F&:!"1*G,?C<!-C&5:>9$BG.65!."3(!8@A&9D/*(@>.:9
@r5181
GACTCCAGCCAGAACTGTTCATCCTTAAACCACNTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCT
+
C4#$/<79DAD6&(C)-5>$?8(GA=/;--($,2:(=./!<2E3<(&-BC+>0"36;+"D1&-DBD@93B!;7
@r5182
ATGCCAAANGAATCTGACGTAAANACCTTCAACTACANGGCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACANGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCG
+
#(*E&;<6+3.%;:G)$F+77E;)G)C39@$?F8/&1/9=GG7%?/F3'D+*6HGHA''G&/DE#+2$D?5&:9!6!)GB,42+;2B&>85:(D%D*'G:G2/@.7',>.C0$GG/33=#EA0:6%
@r5183
GNAAGAACNNGAAGGAANGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGAAGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAG
+
!!)'*#(*$%(+$%*)'+"+"+$'*''%#!)*"&$'*"!'!')"')%#+'+"$*+&"+&'*)%$)'%(&("+(&'&+'"%*%*+%!+$!)%#)$*"#+#"%!)"#'+%&(#+#!#+&'!"('#"!%$!("&'$%"!*%&)+$"(+'''
@r5184
CGTCNGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTACAGGCACTGG
+
146+G/()@@8//2E&$$(7!E5>$-A$%:0/77%@3;43-3"&G-+6*E%
@r5185
ACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATT
+
(<-*;*D)B-*G;49$""-+H1<)B$?$C;G@4FHH>':!!,(*C.0:D*&31@:H'B8D71<%E@DH#;?2?
@r5186
ATTTNGNCNGGNNTAGTNCNGANGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTAC
+
("%*!'")#(*)!""'$"!#%"!'+$"'(*($%$+$$&*(#!(%(&%&#*'&$)"$%"$%++%+++$"+(&*
@r5187
ACACAACATATGCAGTCACTANGAATCAACTACTTAGATGGNATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTG
+
,57<'")E%H,+(;5A%4F5)79-A&=4C/&D$"C-<45%?67:(08=C)7#<E.B)9!/;=B*!6;?:,;26%AF7@12(H1<
@r5188
ANTTATCAAAGGTATAGTAATATCTTTTATNTNCATGGATATTTGTAANCCATCGGAA
+
0E&@D(14)6%2+.D$:>2A"D164$#A,1=*?"(,)F6#@'?;.@9:39@8.D><CC
@r5189
TCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGGAGTAAAAGCTCTT
+
2E'C@:6'.;>(."1+D>4*H.<$>9-B7A$87D6+C@:&D;C&-/(&%24;F:#3C#
@r5190
CAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGNGAGAGGTACACCGACAAATGGCAGCNACGCACACA
+
,;&$1#"AE--6'F/(+263H="E6>C:,(5852A>E3F0'!@"(:2FCE.;%&9<!,D>+">0:C&@,3&'?BG35FC,FA6%0+F"#876B;:-27<.@??14&'5#+E4;5-(&=2$,58DF'-)F-1,()/8!A0*"1'6*C7<C$':5<%&:
@r5191
AGNTTGANTANTGGTTCTCGGAAAAGCCGATTGCGGATATCAGA
+
%(#&!%&!#*&$(#(%%%**+('"#"")%#+)"'((%'+$&!%+
@r5192
GTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCT
+
(BH;0.+D'.#)>>+%*H2$C2#'$",99<857(>F4+G0".>8(4*,.9!%@4-A/"D)'),-+-)B<''?;959F1C"E!A,"A%:38:E3@7'!1E&@9-/:H).@;'DG228.86?+HE!/)/E3?-<!2585/1C=?#;4$4D04
@r5193
GATTGATGTATGAGCAGAGTCACCGCNATTATCTCCGCTCTGGTTAT
+
#7D;ED$,3+&",/:&7,$8*"4EH/E04E#3!40!(>@<#7;+,H+
@r5194
CCGGCGCTGCGGCGTNATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATNTTCATCTGCTCCATCACGCTGTAAAACACATTTGCACCGCGAGTCTGTCCCGTCCTCCACGGGTTCAAAAACGT
+
F.EG(H87H0+<G/>4$E0505+@6>7#<9GB;)'##6=G4%"A,,.,'*"<2)*B8*$(4D#$<)2$'9*"7'C416H5G9;.EH659<"57"'+8C3+?(>6=A=,4#)B)>?5?79=@?%E%D%94(5>1&/9/-:0G942A0HC#!D@$.:,"8!#2%>F$9?7BFD"DC!F(E+CF.'G</(%$8>='0(E?@2#$A3*36<=HA'E6B;%6<7:0>G;1>D+&A.<=D9<+3?5<3;<$=7,80+;EB"F4/EH@8?5A
@r5195
ATCGACCNTGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTNCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTANTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGNATTACCGATATC
+
,03B93=7-*$4/'?1.@/94=,)E1D*"$?",;(0$53HA.92D<C;%,9'#DAG3,4(DD:*@-(#6>E(/8/H("H3H.75%G&F9:@2+@11E-#(08G$6==7,&&80187499H(:0:?;7C335:-9!91&A/&G0%A+?E:A$5B!:6;(83CB6'3:'#:'+@<AF76;(!;!:)0F?C3):!@9)C6.5"$@=7B87'1!05/55;&H"03-CD!<:*$/("!49/;$H:C?C<HE-#AA(:A@=8GA-1
@r5196
NCATTNTCATCTGCTCCATCACGCTGTAAAACAAATTTGCACCGCGAGTCNNTCCCGTCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGNTAACTCACGGNGTATCCATGTCCATTTCTGCGGCANCCANCCAGGATACCCGTCCTCGCTGACGTAATAACCCAGCGCCNCACCGCTGTCATTAATCTGCACACCGGCACGGCAGTTCCGGCTGTCGCCGGTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACCAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTNAATGCAGCAGCAGTCATCCTCGGCAAACT
+
!)&&$"+%*"+(+)'"%'#**'$#+"&$"!"%$!((%!*#*+')())#'&"))#"'$*(*)%"(##"("*+!''&*$('+&"#!#&%)&"%#%&'(%"&"!+!+)*"*"*""(%#&('$#(&*&*'"""$(%*!!"#+(#*"!!"$&#$++"%'&"&'#%+%+#$)#%)&#(!'#&'!(*$)+#')#(*#)&#'$!&&$+'*#!!$"&!'$&+%))""++%$"##$(+*&+#*)$+*!#'$*"!*#'%$')'($!+'!$&*&'"*'&()%%+"(%(#'$#*($!)*%&"!##+)"$((%*+$*#&'(%#*$*$"&+#$)**''&$%#%('("%($$$#+%%%$#((&!&"#%(+"*(#&$"'&"#(""(#*$%!%++!$$#%%#$(!+"$+$(+%!%+#$)$%&%"##+#$'&'!"*$"#$)'(**%#$##%%
@r5197
CTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCNCCTCTAAAATANATCAGCATCAAGCATGCAACCTATCAAAATGGNGAGTTATATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTT
+
@2*F2H;0D5B699@.;2;-FF001B"$C(0=+.,#=E551205"##<9D.@H.(D(%<B2).A%*"2.74;6/%'F<,?94'$D0"6<4"-E4-8)17F$1.H9H;=>5*=>!;)#D;/@(8A2B.#:A0"?2G/.>'>>.G@35-&0:H92/,F!E):%DB#9
@r5198
ATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCNACATATT
+
40<HG)854EC+78!HCH8&%H*'.2((0G"*2879(;1?#7G$="=CG"10,C@&8A&G#B#?>-#C'$=E;!@F@G2$B%G=6>#H@B'5&.-A+C9(&='++1"HE4'->+=,@B)$*:48',
@r5199
TGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGT
+
(">2B1&-4FCH7;;+.&<403##GB:<4@D))6!,1A-?&F8"#-D,7@CD+D7$"
@r5200
GTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAANCG
+
%&?%.6%6'"=&>*#D8@@"&@0+(*1%C@@F6D&84,)1
@r5201
TATTTCATCTTTCACTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAAC
+
%E>-C,(3*(D4C)%=3C,H8$8F9/C%@3/4.6G2DGF<54:7/E-&A&<775;DDAC$$
@r5202
NTGCAATGTATGTCGTTTCAGCTAAACTGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGNCAT
+
++!(#'#*%&*"#+&!!&$('$+($'(!()($'&*#&"%&*!&&')'#)(("*"&"&*#!&#+%$"&(+!(#'$$!!$!!%*#&)+#&%*(**"""%&#*(%*'(%)")&*&)"!(!!%
@r5203
TATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGA
+
>C-8+-%<$A4-%=2;&9A64<5"?9")C+E$@2@FA12/B+7'@00
@r5204
TGGGCGTTGATATGTCGCAGATCAGCAGGTGGAAGAGGGACTGGAT
+
=245*1*H-,5A33BF;32?26!FH*>.@)HAC:+4+G+9"B"/#@
@r5205
CAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCAC
+
,--6D71D80D==HG=H-$7G"CA/=6+>F*,;0*E1HC)?'<
@r5206
TTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGGGAAGAAGGCGAAGTCATGNGCGCCGGGATTTACCCCCTAACCTTTAAATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTANAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCNATCACTGAAGCTATACAGGCCAACATTGAGTTATTTTCAAGACACAAACACANGCCTCTGACAGCGAGAATCAANAGTGATAATTCCGTTACGNTACATTCATGGCTTGNTCGCTA
+
;)BD7E-F)0#H#7A#HEF?:#G.669/,)$@<1B<$@+D!&?!)D220&?*)H5?3A:<6."-7G6B3#2B$>@8+F5'B<-A8E80G/<$F*FD&-;6$C;+FA;3.*-*>'H9?#))&E/:)8(A:"=#=0@0E2AHG(B*@0<9?80"&'B+FC3A=12/+6F0;0!6C&E;&+)%#<(E/:A@@3E?)3:.5D$5>0,-'D)34!7"-69,.DB!1?D/&53'/3:%):1==)$=4.69>$2G2#<1D&/<*,&8HB5B*0@5"8.+G+0D;9(<)B2;=?C/85"F2$+9
@r5207
TATCCCGTTTCAGGGAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACNTNCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACC
+
D@GB)7D/(-#%HD#A!H;&H%48C,*6==>D)>"5<*4G0'8F%=H'&A3-9";H9.(<6,4>./4-:HG)-,1'&E74F"G'9DH;<<87.=?2+'C5G(:9FA0F,@&<3664.8717<046#%>0C#:*+.)A84,
@r5208
TAGTATATTGTAAAGCTGAGTATTGGTTCATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATA
+
D='8?7.H@0,7*'AB>D26E2/)3/HG1'&5A&E#?-!;%"6*":H02D%42,;7>7AA8G$9*$=,?7>2&/%3)01B:*55DF:
@r5209
TGCAGTTGATGTAACAACACGNTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCCTCCGCCTCCCGG
+
53><>,)+"3<B*C+6'727-6*8.?2-)1-@C(8*;&-H@A2@,='70B19A+/B-)1$1A2'!2A*093&:>8$*68F+!7:<&388F$&HB2<BAF09,@*/)#56D78%"C342E6D;&F9.(-54F757"5H$H@+0-)@C<<8'C,6$**&*'(A1,D7"4FD
@r5210
GTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGNGGGAATATCCTGCATTCCCGAACCCATCGACGAACTGTCTCAAGGCTTCTTGGACGTCGCTGGCTTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACCGCCATCAGGCGG
+
9:=A9+'!4;*%==#@,*99!5'B?C;9(0(G+6;9&1A6CEE9=H?70H74%/&+<@)%798---E+%?"5F1?9AD9<4D'H&18;EA%A=>>*.=HD:0*4<<,>=@@)6(1E"<81<-G;.81)-.-FGE.++F8*=E!(8.?HB#.$&;4.)B2;'<+"5?3<4D&GF-"F1*"*=1*(;(FC@4"F&E%,+93#
@r5211
NCGGNTNNTANGACCNNNATCCTGTTTTCTCTCGGTGCCAGTATGNTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGNTAAGCAGAAGACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATG
+
!)$($''&)&"*''&#!#+%$&()%+%$#((*(!#&$&%)$+'##!(#"!"#)(%!&()&!*)#+!"(**('"*'*)"'(+"(!%#+$&++$#+(+#%(')''!*&&"+"*"(+%+)"*(*(&*!$(&*#!#)+(**!"')()'"*'#!$)"&#")#!"#%&"'"%*%$
@r5212
AAAGTCCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGNATAAACCAANGGACAGAATCACCGATTCTCAACTTAGCGAGA
+
+**&'"%)'*)!*$)$#"%$**!#'!)+#!)!'(*&)#"*(*'&(*"*+!$&%%&+($#)($''*!$(*)%+**+$!*'*$#
@r5213
TATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCAAGTCGC
+
8&45?9:HHHG$""@81,>5%2#3!FH1E1F.B8F!44HF2991*.;D$(BDH;$5;07/)4(0H858:"BF%FH:!1>)14?$*(!"=@9GD51".%)&4,.0),H)1F+(&>G66-"@)?>48-#9#F"78?AHC%,,EBF'$<>/$E%5:$%$!7-F3)1;5*<=<
@r5214
CCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAATATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGNATTACAGCGC
+
+(436>DA+@7,40??<H';$-/#F.!?6@+GD@%7G;+&A6)1%:3-,:!$.A"?D@A%0+46B2/(=B>3GA2<<5ED!+FG8,BC
@r5215
AAGTNTTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCTTATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATGATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTAC
+
F/1<$&5'E,'>49B$*8H0,7'4A":('D"3;C%5@1'=>&B05-/=3CE,.F>")3;:/D@<F4'-E!10$D4D9C7F<''05#+":3G%0!B>A+E$/5=G(9H9"+'+100-1>(A.C()H0(.AB#/;*BG;/;-B/+D0;2"%>ED<;;..())#*7340;,7<),0>?5F#DD#%.36+4FG6:4&.@!4":9,!D.01<>3/0F#5+1<G+6")#8
@r5216
AGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGAGATGGGTNAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAAC
+
965D=;942>/#.$$*%FA-)1-%)!:8)@7=*4:5/2&&>;H<A;>"AD#D;8BGA$7F<C<%F9H(G1E..<90$"*9*$#A/0=4"GB#-%"E'%/G%"@;882D->?9>$9>G?-#6G2'.!/G>63+GG93)B2@<C3B&#9F-&H0-!#@EH3!,)BC/A.A(2F58!8@)2;D?,5*HC4*
@r5217
NGATAGAAAAAGACAACTCTGGCTTGAAGCTAACAAAAAACTAAGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTNGACGATGATAAATTCACTAAANTGTTTTATGACAATATCCAGAA
+
$96;B>"%!!&B))45F5D)4)-&B5H,+;#07AG*+$G.?)+5-=!2=%<<#99%B)%74+E38408!"B'G:>G"3''F'8%!BG*D+A=E%4#:($!/>;.H)E2?6/.H6(":1D4;%<;/41'$"-%>3A"F82ADG)&>*@6FE(()<;@06>#3AE-*8B$=7)79).F+
@r5218
GGAGAATAATGGAAGTTCTATGACTCAATTGTNCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATANTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTANCTATTTTCCATGAAATA
+
&++$#$&+!%*#"#($%+#(+'&"!#%&("%"$%''+#(&(!%("*$*(!'")!%)$'("!!#"*)")$"%*$!$*%$+'$'!*'+#)*)!)!*"+%+!'$%'!&#)"(%'!('*'$*'$&#&%""*$#**'$%'+%"()%)&)&($)('(%!)(&#$*+)**$!"$(&$)"
@r5219
AACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGNAGTGTCTC
+
*70#6;+=6;,<2B=="+>061%0-999E'&,2A<#%7GAD=$/5=!:!8";FA/9E-HF2141)G;&;C;?#4:'>B0A9A)"
@r5220
AGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACAC
+
'/..2/%-C254-8)5--B<5,G%-45G7@&1:8>$-(:6E9;'!D69!0&HAH2#<1&C*->$93"!:="C"E'("-%%3=(%F0+
@r5221
CCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCANCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCAC
+
8F)%:4=*$."0*#1!4?,BH:0*E3H:G9D';6F70B7B>#@<@6-",C$>D3&%-A=D7.+/"2H0#5*'B2D'5#:9</#/DA35'6GC3EH&1;!F9=BA/4?8'"<'(E.H,F()5;=)A/'::G=9H':*CH.5H@>/$!>>DHAE1427F;@H<#D5!3?8E,(-7106C#E:B?2A83"/)F;B43@/6&9A*6)8"A.C1D$(%+0D-5/-@@)G;$.<''?4-E+
@r5222
ACTNTNGNNTCGNCANCNNCNNCCCGCGGCGCGNGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACACGACGTTATTCAGCGCNAGCGGATTATCNCCATACTGTTCCTTCAGGCGCTG
+
)!%#($&"!&%(!#(!%#"&$&(&*'()!&$$(!%%"&"(+%$&)&)*"$)+$!)!%!")***+&&!&""+!"(')!$'%#%"*'"$+($##)+**!*&*!#"&')*)!#%'+%*"&&&("
@r5223
TGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTNCGGGTA
+
=)FC!(!::F&?)"(&5)3<AD,G2:)@7$89#;H:?27!BH88
@r5224
ACCTTTTGCTGGGTCAGGTNGTTCTNTAGGAGGAGTAAAAGGATCAAATGCACTAAACGAAACTGAANCAAGCGATCGAAAATCTCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATAT
+
5G4A?B8$!8G,-3HH!7#5@?7.789#@@EE">B7'2'$=/.&:9:C-7F+:3G9>1=@%8?C5FE-0%94C@51.(!.;=,,G9&-F;%E0(()D(@+""B1&*2BA#'EC;*?@G('GA8GF2&913:B@9=7
@r5225
NGGNNNGTTNNAAGTNNGNNNATANNGNNGCTNANAANNTNNGCNTCCNNANNGGNANGANCNN
+
$$"$""$"#!!#$"!"#!"#!#""!!!$##"$!##"#$##!$$$""!"!!$!"#"!#!$#$$##
@r5226
ANGTATNCAGATTCATCCGGCAGCGTCCGTCGTTGTTGNTATTGCTTATGNAGGNTCCGGCA
+
'%"%(%"#*$%&$+%'$)***'!&)"*!!&*+%%((("'()!%&$"()"!*$)$+++*")*#
@r5227
TACATTCAGGATCGNCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAANGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTNTTTGAATCGCTATNCATCGATCANTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCG
+
F>#0D"*<%<B?>:C@8FB#'H?F,%7*<C%/0D/&*B4DF">C5,,-6:3G+5AHH;58=%!?<BB-9)D('/35=>'1">E(-40:>#/?D4#&!:>#!=497"57-+5=+C,%13A6D"1(#-<%<<.6F3GF03))($@*D+67%3#5C$=&8E6=%*,2=('9(2B@4&)"4!;
@r5228
AATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTNTTCTGTTTACCAAGTTCTCTGGCAATCATTCCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGG
+
>>=F;23G24>>211+25'0'DC96>%*2$7*<G'4B@5'9.G28=3DG,*".1-3<>DD<,+#1HB0=0'1*0!?=#/'B0<#7&4#=8;&CB0#4(%C+.C'"EG35H%;0@*B,4*;C3:</G*'*7=B:%@2D'&;A7F*)@&9F8#+8?)G3"$';+!3>"(5+B)7G@(B>*.
@r5229
GTGGCTTNCCTGCCGGTNTCGACTCCCAGCTGGACCGCTACGAAATGNGCGTA
+
E@@0<'D8)%F?*>"=%540..13A:-'*#00.6.#/#95?'.@#$<,+697,
@r5230
AACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGG
+
B!/!0@CC(B6A%)6D,:D!,$$3(;E2(79C$$+@/4@9B$3B=,;+,?8A4#979+>A>9'!G=?2E*
@r5231
GTCGCNCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATNTATGAGTGTCTTCTGCTTGATTCCT
+
'G3,2+&G36H+177-?0.%;>D$-17>E0"$>6D+9H6C.A'!*B"-)6+:+0;"B&)->G4#6E:<45FB<5>9>"0G.+8A*?8F'?68B*'1.@/*2@!C5>B&)>/;4C":G?B@)=1+0(0!?):D-+D7''>6F!$))D!662"+.$8$/@H,<1C5:"<%')&6CA%A,
@r5232
CGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCG
+
>""1A:*'*+0-8'7B3'8H,97EE&.A=6#,+276!A:?,;9
@r5233
ATAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGT
+
<E;:0(D&',"A&@>0!-4=7<'*#9-$&,"B#7>*9A5+&<;@&,G"'.$-@D.8*(05%E>8-8'B8>!B+;$+H-'?*C"C$(!0>/7A"=50(A?1E0;,30C#(6'*<A,)@>9</AB*CA5$/E;H!:7;"=.$/;2EE$)>%#2*;EA@=
@r5234
TGCAGCCCTGTTGCCCAACTTTACCCGTGGCANTGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCNGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCT
+
H>8G=!.$#,$26F@$E%-EA,"77:E0:$+;#DD/.8;9/B>@C>)E->#.8:2@'8%%F7".:H;7=(6,F8&(7+8E8212=4#F/CA8?%2.:A='3#(>)9!26BE3D,32.5G$=7.7>9/*$#)*24>A?5-1C=<."C,:C/&)G48H9">@E>+6B$*):@G511-'C<7@&E
@r5235
NNACATCCGGTGAGCANTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGATTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATCGCGGAAGTTATNATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGNA
+
(($+&(#'(+$#+))$#$)$"$#)!+&(+!*%##)$'("%(+&""%#!%*$$#$+'#++)"!((()&+&"*('*(''&%''&!%#)&$+#$*$(*%(#'"'*+($!)(+#""!*$*&#"#'$*+)*&&#'!(*+*$##(%!*)&#'**&)&%''*$$*'%"*(+"+')+$$"!*!'%+(&+++%#%'#"#)"$%")%(*$!&+)%"%)&+!$&&%#*!%$!!##'"'!&!++&"%$#&&$()*+#)*''*"%%)!(#)%)&!"%%%%&%+
@r5236
GAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGNAATTCTGCTTAAGCATGCAATGGTGGGGATTGTCGGGAGTATCGGCNGCGCCATTGGCGGGGCTGTTGG
+
9!#B(..??&19+(H4!@@3+41A#0&+2!<9@5@3A)5FEH294."")G=>2A<*'<A.)&>+G9)%.%B+577,95+"',0*3*F36@8:)C*H6,HE@.4!'3EH#$,C'2!?!A%
@r5237
NCNGTGAGANGNCACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCA
+
'%#&#%(()!'&)+'!#%++')&*!"'$$+'")(##+(*&!+!#'"$!"$+#&&)&#!+&)(&"!*)'&($%())"#+%&$
@r5238
NCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATAC
+
(>?FG40&G4A25D2,&G("E)2;F5BC#:##"2<3$(5+:@4?#%55=.;E6+G>G+7'6E).2=C3'59@(=@A-50=>$#&-*:.39#E+4>):##"@F%C0B6G9@B,00.*@GA2D+1
@r5239
TTTCACCTGATGAAACAAGCATGTCATCGTTATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTT
+
#'+*#&*"")("#!()(%$+('&)$&(%#!%!+$#)$!%#%#*%$%+%+*$'*+#&#+&#&"+$%)')+*)'*&$+#$'#++(
@r5240
GNACAGCACCCAGCCTTTCGGATCGAACACGATAATATTCACCACACCGCTGGCGTTCAGCGCGCAGGCTTCGATATCGTCGGTCAGGTCATACGTGGACTTGTCACGCTTGCTC
+
(!+%)&+'$!%)!#&&&"$!*!!)&!)*)$"$+##*%(%$'%!$&#!&!&"#**+#(&(*%)&'()!)"+"+!'&'#%(+'%*%#)*++(+(($!&)!&$'$()&%(**!"'('*
@r5241
TACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAG
+
.8??!"&;@D<3>//.3;&H7H4/)H?"A3-G,)D/.0"):<,!:)<<;F$=:A!1G%?4;E.E,
@r5242
GTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTA
+
+)+*("(*!!$%)#")$+&*%)$"+$)$"*#+!"''+)*+')!*!"(+""))$#&((%#"*#%%#"++#+++&+$$'*+$"'%('*#'#"!("$%!+)!
@r5243
ACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTT
+
&9149387ABE-/DB883(*%3;F&11@-!$/$G=5+C<(D%&50+550&?B>)$:4F&G,H)=C4#4<,5=5;-CE8'"(9H/;2H$*).,27E
@r5244
ATTACTCNATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTNCNGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTG
+
&>H/0FE7=C/F9!D8>&7>B+122"E@>2$!0'A)46GB:0&>"ED4#:F9"=!G+H$,:G25F'&@$DF/96<1#*(#/D"F+A;1,3*065&="5*13':;@=G@($&%?/"=H.,=G?%8FB"3H<*BD*$G?A9/!?2;<F
@r5245
AAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGNGATCCGATAGATNAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATNAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATG
+
@"B75+A+,=!%HG#?2$.$%/5%>;7+3G,)%8.09$9!<,;0.5H-G=%C)H<*6@99H=:4@/,%$9A-9*:?>A))5&46>D"+$<-H.+5:8AEEA4/8.7,%:'1%3B)6DH'!$,@&D66,,7C>=H63-E/>D0,%$,HA;A<6G-!$/8/8)</<H26)<$&7)C%(!D#@B7+=*97<5=>(EFF+D)+"()/9(G,7(3
@r5246
TTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATAACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGTATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACGTCACGNATGT
+
FH&$A!+:6#:A>>BE,(+*2#(1F+9263%B+);,!((GAF$=E&,=#8,7D8=$/1=B::%'%5"706488%&06F%+1D(1F@?9#)0/(2(,'6"@!<$7->+55&$GFD#AA'B&33/4H58+?H0C:)8)4#=89)C0*!";3923/F"->"16."E;G,/1E%2B')'$9:#*>,-<.5B*64-8"75--*AH$29B@=6D19&31
@r5247
GTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGGTCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGC
+
89H.5.05-F7(&2=12?B<!:,B=):@F!GB80752H,1=G-8);7)@0+71C9D0"@3.,$486"%F490H55<(D.D4375<4$E9*&.,+/!3G6)%
@r5248
AGGCCGTACTGGTTGGCAACTATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGT
+
G%<!9#.C*%C)9:)D?):@CEG"5B1:<(&*GD>"=-,2.@++.?,62,8@@$D<9&=!@A64%<45B/.
@r5249
ATTNGNATNNTNGCTTNCAGCNNAGATNNATCNNNNTCNTCTNANACNAANGNTNNCNNTNNANGNAGTCNGNNNNGANNNNCCNATNTAGNNNGTNANTTACTTNAAGCANNNGTANGTNNCNNGTCGTATNANNTNTGTTCNNANNGANTGTNNCANTACAAGNNNNTACCATAAC
+
$"$!"$$$$$$!!$#"$$$"!!"!!#"#"#$"!#$#!!""$$#""#$"#$!#$"$!"!"$#$#"$!#$"$$#!!""$$"$$!"#""$!#"!$""!#"$$##""!#"$$#"$#!!"!$$!#!##!!"""$#$!!#"##"$#$#""!#""##!#$"$!$"#$$!#"##""#!"!$!####
@r5250
TGTGTCNATACGCGNNTGTTCACTCTGTGGTGCTGCGGCCNGAATGCGGCGGGCCGTTTTCACGGTAATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTNACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGC
+
$)''$$!'*")'#*$%")$!()(%*#&#*+$)""#''"$)+&'#")*&(+'"%%#"&'+%$*)(+%((##"()!!$'!&#))$&'*!#"$))+$)+"*!!#($(!)%$#+*+'+*%&$(!"$+'"#&*$$(%("!&"#$(%&&#+"!%!!'"#%$&+&$!((*"'*+%#%#'('(*('!!+*&++(#*&'&+)'(&*()+'##!)$*$$*)*)$)!%+*#())&#"%#''&*+")*#(!*#*)')*(+%&+'&+
@r5251
TATTCACGCAGTACANCAAATCCTTCCAGACCCAACCAAANCAATCGNAGTAACCATT
+
+@70@%."9BGB4G6'71E7"E.='"*5>G%%:;BD59@%+&.!3&+4A&54/6/*7?
@r5252
GGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGGCCATG
+
1BHF:1,G&A24*&,A0/G@'E,:E.&/-/!&G*'6<685,3.%F+%!H61$FA7:E3B519E4*?%0-)>1(?&2/-1;'G8G,46B&;"%<E8F<5)>FE3A11%-5$C:%E,<
@r5253
TACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCANCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTNCGCACTGGCCCGTGCCGTGGAGTAGCTCATCTGGGCGTAATNCCGGGAAAGCTGCTCATACGAGACACCCAGNCCGGCAGCGATATACCGCAGCAGTGACTGC
+
50D8>.-,-H+-+7'2.,&,+0=.4!#!-?D"#)#;&#@0G+'6!?0>B4D+92=)')E7F:B%2,37#7*"6%G6$7!)08.(@-#B(5?3)BG".63::3=%?7>E.G0A;A#($@3*&)8F=%"09<HDG/43:D"4(>!$@G3).#5<0?)!HH?>"3=<H,0):*1@F:CC-44)7'4#6E@CG3(/5E!..<$A*$?@+@FB?A&2$H3E'D/83466B+38:&%C0741E+6A",GDH3H>%G4%3>D,'
@r5254
CATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTCAATCCGGCACCTGAGCAGGCAGGAAANCTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCATCTCTTCGCCCGTGTNTTCAGCNCCGGTGAGATAAACGGCAACTGCC
+
1G&#$A<C"/2C7F3,$AB!<'2HG/+$56$5&&DC3?6.GH$8F?2'H=3?:E1?H6G.>D!++2G7?#,1>'E($<5*=B,>4<C+/A=&!9.2/6/%8F-!??5@'C+.@.:>7'1=E#3+A6275A80)87/?5@./'(5,CF:F1**:0179
@r5255
TTNTNGNTNNCCNGNGTCANNCANCCGGNNCNGAATTNCGNNGTGNGTATNNNTNNNNNNCNNTNTGANANCNNNNCGTCGATCNTCCCNNCCCGGCGNCNNNNNGNNTNGGNTANCGGAGAGNGGNCCNANTCNGNTTNNNNNTAAACCNNNTNNNNNNGNNNCGTNATNG
+
$#!$$$!#!!!$$#"$"#$!$#$""#$#!!###"#$#""$"#"$##$###"$"$##"##""!"#"$#!#$"!#!!!"!#$$!#$"#$#$!!#"$#"#"!!$"!!!$#""##!"#$!"!#"!$!"!#!"#!#!"!"!!"!#"!"#!!"$!$$!"!$!"!!!$#"!$##$"$#"
@r5256
ATAAATAACAGAATAAACGCTGCACTGTGTATTCATNCCAACGAGTGAATACACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTT
+
$7H)#"8%@/:)F;>&;!($$)%46/>?DA4(=.6)0'(2;($++GFB--2H.F1F/6(,C'7B?='B'H%19D;=C541&=)(,6<85)8>0"5(F-085+#4%#.5%)H&+'@
@r5257
AATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCG
+
<BC4!%(=),/&@H'$65"/<##@>4H(.GCE$"1)*18F6-$6@0/
@r5258
ACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAA
+
HE*FEH@1%>?-,-./90=0'-#/-D+:D71H706H!@'&38)6,96&%8/9=,'G<F9*#@#80=@=(HA,=A0;63H;"E7)1+G=
@r5259
GGCAAAGCTTGAAGGAAATACTAAGGCAAAGGTACTGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTG
+
<;>+.CG<!"HE6">*5D:!C&/H33*<>?(?D;C4#/1,0$,</*3.):H-%9D?/6"F,;F=E%7$=C5A+B@0>G07B&BHG.)!5*%A=FDE%698%!&&H2D%",7D.+@,#*$.FD#*%!1>(:*.:2,+.1380A=GH)?12A/D?G
@r5260
ACTCCATATGCCNNGNNCTNTNCGNGNNCNNGCCGNTTNNNNCNNNTTNNCNTCNCNCNNTANCCNGCNGN
+
#""$"$$#""#"!!!"#"!!!!!$##"#$$!""!####!!$#"!!$$$!"""#$!##$"!"$!"##$$"$!
@r5261
ATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGNAA
+
."$H:69G.-D1H<.3E,A.6#G();;#-9*7$4D/>!&;.%#C,,,H-A.7(?80AB+>&,"==*BHFA.C$:?#4ED/),.D0F,E:68#1*=7.6+0CE.-$<;$!B'()/07<-C=;=
@r5262
NGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCT
+
$1A.E<5?5C<"=DA8@5;C9BF32+%1+*<;+B>;%+2">F3
@r5263
AACAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAGCCGGCATATTCGCGCAGCGATGTCATGCCGTCCGGCCCCAGAAGGNTGGGAATGGTGGGCGTTTTCATACATA
+
G?-F2=?2&@.+5@@+6BD>E<)C5F6)4:A"+AB$'3"0+4,A85H)!6B#1%CG'@%>EDG"3G,$7H0<H>'4GE94A8=&:&6404<5E8@*'=5$%457HA!0@C*$3183."DB#C2'.;*8+4=AB(%8&$>.G-!0C;!':7>("&
@r5264
CCCTCCCGAAGTCGAAATNAAGNTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTNGATA
+
D!@*E(C9)G2*G-B/)D>D(B48%C0A75-4/+3(**8E45;)/,!$12-'H6E0)9+;1"<*,%<0,4(G-D&E&3=<8&#D)=<E9@7B32-A6#,."8B?CF,=!
@r5265
TCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAG
+
"$+(+&%!"!'+&+"#%!(&&$"(($+*$"%+(#!)%#+#"&!
@r5266
TTGACGCAGACCTTTTCCATGAATTGGTAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAA
+
A4:<:!D+-A')$-G>9),1C7C*/@<6'B,;B2F0D<8,*?43<98#CE/FB%E@H!5H2()@B75!373>/DB=0)D4CG*2AH.0>&"CG+1='<6",FEG06#19G<"?3%H?<8!)6."$;CB!,0@$167G#)7/A>D!)A9*78584)*95FE=.)2BD
@r5267
TGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTG
+
"&1;5+87.</%2@D;<7%/(!7F2B<2%0/>(85+&:01079-/!:B%?@B
@r5268
TACATACATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACC
+
E/45DF22-9@C<<7',+B-E&)3G2&)>G$!/%!6B1"9.,)*BB#
@r5269
ACACGGCTCACCTGTGTGATATCCGGTGGCTAAGACGNCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAA
+
$"-!"9+.3;G()6%BH0D07/B!?!+D,8'D!H3*14+38B@35(5%.!E2C>)>$5AEC=3*#(B</4E>6@&"2*7;37)F:/?1:4),1#,0'&0#:*1=#"3:/E;A9(82-
@r5270
TAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTG
+
3&C8-.37F7-#><=1E$8+&<-A1?(5B1B'0,3?6:*87DF9''HBH7&7A>?D#+?5:96!''*@,$2AD7,7'$%<7D<F>56E%%%:1-EE@(
@r5271
TTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGC
+
+7#3%B-(<,38C:5'(5$..)AF(:))>3F/'FD67"A:+9,%!%$#<5@17-#8@./'#D=+>"$@.)A:
@r5272
CACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGNTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGA
+
#B010D5H52,,&<8HB-9=@(64/C<@DB-%0$0#3D@8*!2B':483:@B72%A,$?%D&"D/FBA-%'FE<)!*4F"F:1B(B+HD?)$0#$6&)4:4!('99=*??,?B.35@.5??'#C;?B5C031$<H38-9)
@r5273
GNACNCGNAGNNGGCGAAACCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGANTGCATTT
+
#"%*$##'!'!!+$$$%!!+##()%&&$&+%+$*"%++$'%'))$!"#!(&*+*#&"'#*+#*((!%
@r5274
TTGCACATTATACCGAATGTTCGGNGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTNCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGTGGCAGGAAGACAA
+
+$'')!)*(+#%$!$"')&""#%%$#+"+&$&+'&+"$*")+'!&%(*&'((#%!+&!'(!#&%((+)+')+'#!)!$&'('&')++'!&#'*#)))$(%'*"'%'%!&*$#%$+('%")'"*%%*"!%(""+&%")!$!'))%%")'(('"+))(#%%"$#('+*&$!&+$+"(*%((&&)'$)!'$+%$"%(&('''*""#"&#+$(!%#&)#(*)%*(&*%(&%"!&(+"(#$$%')&
@r5275
NATNNTCNANTNCGNGCNNNCNTNNTGAATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTCG
+
*(*%*''$$))!*''%'""!&"'%$))"+!))+%&"+%#%()'($&)#*%%'#&'!&#*&'($')*!
@r5276
CGCCATNACANTCGNANGGATTNCCCCGNTGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCANCAGGTCA
+
'&"%"'!'%"!!%*!"%+&"&#)&#%($#*#%#)%(+!%"(#+#++&**''"%*&#'%(#%$!%!&)&'#
@r5277
GCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGCTGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCAGCTGGGAGTGGATACCGGCAGGTAAGCCACACGGTCAGGAACGGGCGCTGAATAATGCTCTTTCCGCTCTGCCATCACTTCACGGACGTTCGCCAATTTTCGCCTCCCAC
+
7(=%."-+&5=B%A-*B6$%+05+%G-09:&8C>.-2C+@*EH?=BD?631/$@64+$($!5G%'54.)9?%"<.&%11%":%9A+!+//6&>,6,$E>6@5'D=B/<$<0A4B'%8(-'1HC;<>-?19B@F@%,"BE$/"1'3:<6::34!*@00<-=%/9+!&CD:H/&1###46-%@.10,21H"@9,H;E#G>!:%&?+'*63!82%3=<CC'9A-'E=9H':9)?
@r5278
TTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCC
+
=2D''*@*=('?2E147CE6+BH4*.FC!,'G&4=23?,1=E@
@r5279
CCGNAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTAC
+
5?<70G4:AD!F=6%3-A%G*71!'6!D:?+0"&'*@!#-=3D'D8"$%:62!(D"5C*,E.EHD>G5$%&G=G**%A$@;:%,=-?927B'9$GEC@0?4A=<F7.<E4B'-D;">C&!+;.G
@r5280
GAGTAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAANNATCCCTTTGGGATTCTTGNCTCGATAAGT
+
,-017+77:8FE(&/,:!5##<C'1:"&<4,5(#1(;!F;56H&9.44D")$5>!+-,>:%!62:?D$#F3#1:,4:3<1
@r5281
TTNANNNTGCGGTAAGTCGCATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATNCCCCTAATTCGATGAAGATTC
+
**"#"$'+%')"*%+$)**$)%%!#!+#(!*%($(*!!')!(+%))""!&"%)!#!!!()#+'%&%+*!$&"&!$'#&)()&#")"'(!+*"*(&#%)#!!#"$
@r5282
TTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGNTGGCAATTTTTACGCCTGTTTTGCTTTGCTCGA
+
G#F802,;H!2AD>:B=G25E&':)55*8BB4?*-*7?E#2;(;(9')%!C.4HC%!A4=*5%#:.H/;()!4,,G<2C<
@r5283
ATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCC
+
@!6H//HH-AD&B"G+*:EG03#A=6*19!7F"?@6"%=3*83%(#-C;)/.-"%#'86BC,(%-8'E8!B6A:3E4)->/0;;86>=633(C"?*E+.$1
@r5284
GTCANTCAGCGCACTGGTTAAGGCGGGGGTANGCGGTGAGGCTCAGATTGC
+
'#)%+$(!%")"(%)$*&&)!%"!#&+!#%&"&(!)"#%$#"#%$*!!$#!
@r5285
TGNGTGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGAT
+
4+!5@;"CH"'87:;7:+)D(A?$);C94A*0%#(<H+=#,*+CG*9,F>;2D3:F5!F"*+A6<A1()0BG'17%=@1973;(B9>9,!*/
@r5286
GCGGGCAATGGCAGCATCGAACAGGTTATCCGNGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCNGGCCGCGTT
+
F+8#1D)6<"E+!@$A=/#&"1-=B"(*)5!>803(%)5(8(4'G@3?EA!4AF:=8.*&D>947</G,D)7@F@21E,.E/(7E$.%B&
@r5287
GGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGTTTAACCAGANCAGCGAGTCNCTCAGCGCACTTGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCG
+
D-1*A%/#*&GCFAD=&%C134AG7G5=$$B>972;2,(+"79H4$)*:A-+?A"%--'./-#4F!>>$>AH);?BG57CE:#C=()>0;H%0.%A,(E'$C)5CG(5?FGE530<5B.&'G@#>%GH'
@r5288
CGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGA
+
,(-23B?*0AG!(38$&:;/C"<%C,@73;><)&+5H:4H/-;/5&%D"/7C,E7%D.:+DAB438<&:;"!B=F/1E/#0>D?G32D'1-!!!,'H-=(1E!=%-E!%=!6!'?*B8&",>A13@3%/G)3A1@D.829-:'EE81@.B99)#4>;7G@(.
@r5289
TACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCG
+
5C72?A9=%..9(4.*E8A>"3B'2<++(-CH:#)(8%2:CH<1)<:4>&@*380H?A;>/8*.BDG+8881@=.
@r5290
TGCGGCGTGATTCNGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTG
+
A/,1B@6'*H'0$;3/H=G?;:&/F(139:D%D43*0'?/51:D7G6#)+HHD$$+6@9/..2E2$1F(AD;,.)*H=?$+3;C)A9;>!-.E7F759.%$FH=*#7"?)+0@%3B."@"
@r5291
TCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACANTNCCGGACAACTGCTGCGGCACCTC
+
"G'"06G(9/$86.C-*/A<:5*#%-?H+&>-FHB2F3H<>5?2A.>;:,%"B)HBC;H9'%)&,!%5:'+4B8,G,/0#@#32"6-98+71CE":055
@r5292
GGNANNGNNGANCNGNAGNGNTCCAGCGAGGCAGATCTCCAGCCNGGAACTATTGAGTACGA
+
$)*$!)#&'%*#!"'"&(!&!"#+"&+"*#'!*&#&#(''#!$*"'+)"$")(##%!(+"()
@r5293
AATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTANAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAG
+
5F+/!@"+D2EFGF:C$(H5--%4*G0B#<3)'.(1&7>?3)5+C8"G,?B;!)!9EEHC'G,DA*,$%FB5#;(H';!#;,=&&.4A#C23:0.1+)>'
@r5294
CATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTG
+
E'CC#+A:$;>@=&55+GE+0;.(FFG2+,H8E;&1#+<<&<74-7+!(G90?G;%2+D##10:5D5H;43'0
@r5295
TCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCC
+
G25!D1GE9*@!A!"BD$'3-D41)4;A+4##6?3!D@<8"/A3FF
@r5296
GCAGATGACCTGGCATTCGTCTCGGACGTTTTTNCCGCCCTGGCAGAATTTTCTGCCGCNGTTGCCGGGGAAGCTGCACGACCGGCACTTNATTATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGTTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACNGGTGGCNGCCGCGTTTT
+
$'+&("+&!$)%+**)!"#"%&($!)+'&)("+#++&#"$)++$#*(*")'"))"%&$'"!&###$%'&+*()*"*%("&+#(++$)#$#(%((%)%'""#$($!)'(($'$####"(&"&!)+#(&%**+*%+'%+*'+*%%)!*!')&!*('%%#+##'&)+!*#!'%#$'$("(*)+%'*!)%$))"$+'!$(&(((*%$*()*$!'&"%+#'$+"$!$!*')$!$#+&!&)%"#%(""#')'+$#+)'++#($#!&+!'&($$*)&!#!!
@r5297
GTGNGNAAAGNANNNCTNTTNAANNCCTTTACTGNNAAGANNCAAGNNNNGNNNTNGTNCAN
+
"##""!$#!$#"$"##$""!"$$""#####$""!#"!!$#$"##$#!"#$#!"!#$$!#"#"
@r5298
AAGACTCNATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCCCG
+
?=AF'H516*1,B;HG6>="--5#=-,$AF04'"4-B9.+0@H57(.<=/
@r5299
TTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGA
+
8.(41':.-4-CE&&;?H<!@(<),!)"+H5#E5)C$&)4A05B'>G9F3E<(577!,E'DG!G)HD2:B'E57(:F:=6(,@((3B/*)<+*+'
@r5300
TGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATAAGTATTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGNGAGCCTGCAGGAAGNGGATGGTGCAGCAACCAACANGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATNACA
+
,B-,/3>#>)6!!7'C1-2AA#'?D:>390'9A=-BH%78A-))+3*)5<F>0-->0<0,1B%.!<'*7*#@@4-9B+/A:.>#=H::1G@:("&;:)6'7?G(E;/6:8,'D+HE3"%!D2=4G@&59C@*=(<0A)>(?G2>@;A!<"D;@H?(!#H0:218+2>9+<HC/2G:3,90=#5-0%.!&"1>'9$5A:CGDG;483;8?(?H$;)(7F;*B3/,8H21-5A&&"2@+2AE:<A4>@,,+<E!*D*1FA9*:B&A@35
@r5301
TTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGNGGANTATATGCGTCACCTTCACCAATAAATTCATTA
+
G/8GC97?C2;C$C+8(:>9)%;HC3C4+0BHHB5$!%%!+&;-8C4<C,&8%C)(E,67D29H<?C3E$=$)(C;F-(&:%-3HH#571(2B?2(630H(/:C%4=:?+8HE@>&+?66-$#C/,*;;9!2:0E;>''4"BDB#
@r5302
NNNAGNGNNTCCCCNACNNTGCGGGNNACNNNTCCNATACGNCNGGTGATGNCTAACNNNCTCNNANATANNCNTAANNGT
+
"""$$#$!!#"$"#""!!!##$#$$!"##"!#"!"#$$$!$"$$$"##"$"!"$!$"#""!$##"!###!!!$$"$$""##
@r5303
GGCNACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGC
+
;>>EB,.)0&+<=?)B;4)15/C,H("F!*5'**<(@*1D-.0".(6-#2.<9%C;>=5
@r5304
GGGTATGCCCCTTACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACANATCCGCCCGCAGGCG
+
)'+%'"'()#%&#!%)""#$$&'")*($*#')(+&($%(+&+)%'%%&+!")!)'*%($*+'"$&#'#+
@r5305
AAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGNTTTTTTATAATGCCAACNTAGTATAAAAAAGCTGAACGA
+
G&-H3/DBB2$A=$*G?#=5-1,&>41:%1@5G.+#4E6>#%1F.70A+=(%"-G"?+3=(G!<C06=,8'$7@<.B92#0;(51"4G#)DD-G<-)"E'E1(1=290G5')
@r5306
GCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAAT
+
.5:+@$A3!EG42!<0F/G<<*/1/*GB984$0=;"##0,!%D,#:H/+6/++A
@r5307
TCTAACTATTTTCCATNAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGNTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGNATTGATTA
+
'C9>)+E)?(0*""0%'9FE&&?+=*1%<,D61+H9F#(#80-=5+8/$&4,"+;6AE4H&7=%?-&:D7(A,7G1?%6G9DE=H+2FF1!A%13E19*2@1&)'=F6@D;0AG9(>?'<117=8.%?'9@1AB"F/G/6#%+4:&@A3>4:-9@,74*<,.7:B+0#69,#0.80A/9:7>2C<>,+G:3B6:.'.G$5%!E#$:7>-(9444@0<B1@4E0G'&H?!,1:+@,9830*F!5A8
@r5308
NTCAGGATCGTCTTGAGGCTCAGAGCTGGGCCCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGC
+
!DG;8E=3;444@0H'(8G!#$G$/3<67G2&G341@B7,,;8CEE#7D."2!-?+A56"*'&:DC02%C$C$;A!B):'>3'B/?&8><'EGC9(,'
@r5309
TTTTTTCCGGCTCAGTCATCGCCCANGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTNGCTGGATCCCGCAGAAATGGACATGGATACCCCGTGAGTTACCCGGCGGGCGCGCCTCGTTCATTCACG
+
$G1.:3E:A0D*7+606ABB#>C,GDG1#+>@&!"(!+G#=*<*'+2-"-8C8&H.;2<=@'B7-F@?&%:9(%)(8C36,3":#;H(F."C8B?(7G.@D>G0-@-(<+@@E>@*+$+EC9*#*;!!+D%@@?;?!*756?>,B/$#72-714'#=*A%.)-#4)=3AB"9'8FFA4,G.5*<,1E)"F7A37()"#29,GG<F'8.A"GH#FBE9503&"507@<#-&-"7?G&<4#'1--F25A'@2A)6/G16:*)-BG/.%;&2E76-7)8C#/;/EB"!0?(%H=C<.(*#;7(>F"C1/9<(3!>(('*#E6EH;C)%8%;>./(>5$/*979<-@2+;A#.%CH&?90<;(*799E@30*%:9A.;=D**&(A*/"-4#<8'3641>0A)F:1AAC2288,:&:)CCF@D,5,<A3=G09'<;"8,#5+$E#@B@?C**=*:=4-9(
@r5310
TTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGC
+
E99'*H"F,!)$C<C-&H..B>75>>%F+#=:1#3'+(0%7,,>%6!CE!G!40F7:7#%9#;"(EC%?0,0&C43?E+3H!
@r5311
CTNACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGNTCTTGTCGGTTNCGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCNTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTGCTGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATNGGACTCAGCGGTCAGTTCGCCGGGCGTCAG
+
=808A@&1E?:.+A%4,3#48#G9*C#@1;-6DE0;&-!B.#6/)%D0#6+@/$FG'?B)4A,;784.G-E!38>A;/3$D!<,:AG/EFB=E)=)E4F>/.C>:&EH5)6FD2G'/,'+%+C*>#)81#%1&+H:.041='F-81&D3)<6F(73F./2**E"(H+84C#55@*B-77:4(/0(&7F7F)*G.-$5!*<86:(:0*7-*1B"*;8.#9-=;H2*8AA&5+5?<1#0C%,'7+*/F*@D,66#/:@?",*:)7E290/5F3B;/',DD7)31.$##@&799/7A<2%/>##7%<$9"#A82,,A&,=+'/-=;46.B@80@"$B9*(03/5?1B3G%4&!:G?*'?$?C(22B?&#<=$684,'#)418023E4>9E=,;?FCG8)@&-:)"A!>:+=A7=/9!0G@<?$(3F6=&3BE'<?)A026E-(1#5@<F!A88%;>*)("(-)E<EA8(7A<0HF0)>.B9/$#%!2H*'C@./1A>578
@r5312
CACCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCTGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCACCCTCAAGCGT
+
!'-?:/>')0@(9E@H<4)B>7@.A5/GC-E72H599!.1*55.E7@@(%CC35'.!#:++?D!@D9H:3,19)BH$713@.D,12:*>@B49D5-A?&/6,8"B38%2"7(6*)*7'=34,B$,610/,!9H=#?254.:%9AG7A;-#85<E>86CD":E'6-/>:GD$8>B)#-2""5(*,'.A"4-==B*)&<?30B580&%:>DD0B0,"?B%EEB<>(+F;B))?10A(6/&-*;HG28;<>@
@r5313
AAAAAGATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGATGCGTCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCAGGTACAGCAGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCT
+
;8*!A"(H::6D*9E#D'-5/?-:GH82!(>/&B$-HG74((4'C5$D7*2+C#?=9C*(=(=895"#6E?2:&$1+D(295H7H9.<=06G2G(E&A5(9+7-@?7*#$5/<&<%"+=5%B.;C%/:/B6$45>'887A-9=+7':$>&H@A+"EH4":"G"2"
@r5314
GTCAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGNGGACCAAACTCGAAATCAACCGNAACAAGCAACAGGCCGGCGTGACAGCCAGCAAACCAAAACTCGACCTGACAAACGCA
+
"!B?D3E*!G7E>G,..-$7F#F@66,A@$$"!%B@*4;,A)H*G+C2"CG,<?#)#9G(9-E-8F6HH)((A%."-$;!42>(706(0C2>A1/E;3/F9H1",F9&?:&03%=((/7615?.65'0D92A
@r5315
TNTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGATGTATGCACAAAGCATCTTCTGTTGAGTTNAGAACGAGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCTGGTTTGTG
+
&"2B4F"5'9:&!FGH($1>)80B'H9$<:/H&1A;D?HH;$:?9$'".?<G!CDH&;#H-=%4#*-2B15#(%,+E%=80D@<!$'D-6;@.)7D%&-;7'-:./>FC>;D=,5!D;$-B922H=%-:0(D2:9/+98A&2(590HDE
@r5316
GCACGANGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAAT
+
-G,-/-7#8.H)$:801%&*H%<C7E&3E(@:BCF1D90%!,8D#$>'%E6E
@r5317
GCCATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTAAGCCTGCGTGCTACTTCTGTCTGATTTC
+
G2G9".@*(4)05!,)8):=1G;//D&9';;>=;$!<5>563EBF&/9%;D!H;GA6G88>29"3@.3$0,8823.;9#@0E&>:)A%!61?4B/%75"#=9C@!996;+1&%*47*/1
@r5318
GGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTNCACCACCTTCGGTGTGTCCC
+
)5'CC4#F&"/>'B&33>A0G(+<&(84G9<#BG1A!5=:&2'<2A1,)>%'7G"3+&94A'/G!:-4?CHA-E#<=43.G1",&"BDEE:"(#A:8'#&!"-F;/*
@r5319
NGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCA
+
-"-%*3,&6//&C0*@A",C*:3C(,#3?/0G>#;/21(/F;0($?,H&"-GG+4'"$0&)C$"2/*64!FA;50A.9!)/$:F%9;E(+!$:;3>
@r5320
GCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTT
+
;0/6=1'#DE(&C&6&-?0*C4G(6G45+=BA&C?2C<+0.+;1C?-C4%F
@r5321
AACCATGCATTCAGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTANTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACNTT
+
)")*+*#&)!)"""!($*(*%!(%#&""$+!'#'&'))'+%*!+(#%'(%($*%"*+&*)(*#!#%+$!++"%(*"#+!+'##&"%&++*!++!'+(!**%&!+)#$)*"'%$*+&)+'&&(%%(&&&%+)+!$'%#+()*"&$&$&"!#**&&&!!+&(+$(!
@r5322
NNCNTAGNGCTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAACTAAT
+
"*'&%%#(!$+(+"!!"($)&*%+!)&%++#%(#*)$&!##++#!!%*!*&&&'*$)'!(+!$()#)(+()$)'"!+$')%(+*#$#$$+#)*$+$"'$&("'!""%*&&&!#!)#)($!'+'**("(''&#((++!")++$$$*)"*%**$%&"""*&"(###$!!'++%*#
@r5323
CCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCNAGGCTACTGTGTTTAGTAATCAGNTTTGTTCGTG
+
A2';!%0$/GEGF/@CF@C"<G=?"#/2H*#7568;#&A=%&G6%91A%1;%'2-*-/-*F-E/BB@<57!2H6D',A$FBF1,91/!&-;,2?4@%A
@r5324
TTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGT
+
($)&'+"+)%*+'%%+)+")%%$"(+#")+#"''*))%%$*+)!*##(%*%*($'"*#+''#(&()!!'+#""+&!%(&$&))(#"##(+"#"!+*+(&&&*'$#*%&#!'"%)$"(*$!#')#"&+++)*%''!+'!'!&!!&!)''%!**))#*$$*%&#
@r5325
GTNTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTNTACTGCTTCGGCCTGTGTCAGTTCNGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAG
+
%%$+%'(!)+$*#%+#$&($#)#'*%)"+(#+#"%$$#)$"'$($(%*&#!"#$())(&)#''+%$)*(%(!%'&)$('##(")&!"%#$+&++'!&")&$*#$"""+)%++')##'+)%$!'
@r5326
CTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACGAATACTGAAAGAATGGGCATGNGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGNC
+
'+#$)$)+%%%'"!(&'!#)%$"'#)$!+#%&)*'$(**)!"!#+%++#"'((+()*!%)%((#&')&+&#(+#("!&)"()$*!#%)!!"*"!#&%!&"$&%)+)*!'%+%!$()+"+"'%!*!"&$&"*#&+)&(%!&(("'
@r5327
CCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTG
+
?2%?,67:B;,15FB?$/<%;80--&(!:FH-1>G,1.$D+015,-8(&.#G4;E/4E3!=50*>-2H7><#1?G7!CH)8B3+>3;4HC/F-3.*5A$;8C6
@r5328
ACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCG
+
(16=B$G5'%-0=78"61+H17*HD9)*F9.$84"02AEG6G%0;*)'.H=3(.#@6C+/(78)F6$0"E:
@r5329
GAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACNTGGGCGGCTGAAGACCAGCTTCGCGGGA
+
D1%,;=@-G/B:658*B=:F/.4*!%<??3C&A3+6BB(&3/&7B@/+)H.%H!?&6:7E#;6DD=3?AC=#9B>73+11C>'<4F50?CF"C"0A(+C2-@%/2908%GG?
@r5330
NTTACCACNNGANGAAGACCAAGCGCATGGAGCGACAAAAAGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATNCTTAATAGCACCATTTCTATGAGTTANCCTGATGTTGTAATTGCATGTATAGAACATNAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGNAGCGTTGGTGANGCACGATAATA
+
'*$&$($'!#($#()#$("'!)%%(+'((##*)''(#$"'%)"*'%'&+&#"#$&&"$*+$$'$'$+))"(!+$#(#$'+!"*#!!($*!$!'#"#+&#%#$%()'+&+*(!+%&&"%#%!!()&$*&(#%*&(+(!*$#*$$$'+*"+#*#$!)"*+%*&*$"*))#%&)'+#"+'**"+#"%+&*&%$$(+(&!)'*#&%%&*))*$(+(##
@r5331
TAAAATCGATGGAACAACTTTTCTCTTTACCAAAACAAATGACAAGAGTC
+
H'98?>24760F8$"@">*<!'",D*!D%E56!5#5G":?CD9-))CD2G
@r5332
CGTCTCTTTGTCGCCAAATTTAACATACTGCTCCTCCCCGCAATGCGGGCAGGCAACATGAAAAC
+
,>.)+%$.424*?/?B%9&5;C20!*$!;'51>D@6<;=71A'':)@">030E""B+HEE4E&6/
@r5333
CGCGTCAGAGCAGANNAAGACCTGGGCGGCTGAAGAACAGCTTCGCGGGA
+
%!#)"''#)%''%)$''+!!#)#$%!*%!%()!&"+"+#+(+%$%+#(++
@r5334
TTCCTGTNTNGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTNGAAAGATTTGCTGTACTGCGTGAATAGCG
+
/08,@,F<?8":?;..32F)9#4ED.(#=?9F?'$D>;3)6G3=9.6+GG-$$,%(@;!3-&G/#EFG?,7298.26+A1=8/+EAB+'.A.$E@(
@r5335
AGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGG
+
8%>BEB?(9#.9&,,6!<E4H;-!++G.'H+D-="<05/;;@<<DG?(15>>.8!%G;,1)+.H%/C$6B9F%AE?*@$?CF;42A>0#@.:C9B=)@";CG."@-8<-3;H>
@r5336
GCAATCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCAAGCCTGNCGAACGCGGC
+
"A*6B,7A*-7)'#-"5D5&7#*F$9$7+?"3#)H,3!:"-H=9+=E2)D?!9&64!%7!@5E'>
@r5337
NGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCG
+
#))'+!)!**$*)$&+%+"%+)!#)*(##)%"*&""('%#")!+%'')"!(++&)%"%**++*$#'*!*%+('#!(*)%"&'$(%!+###(*+"+*!*#""(+&!
@r5338
AAAGCAACGAAGTCCGGGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGG
+
/"#=D/H@@4":EG621B.G5@BEG2,$F@4C)<%0(0>HF>8)=9#*:BH*7/"%&E:BCCE%!H7,'@7%+*%A?@,+:3-=(<5D9+(66
@r5339
GTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGC
+
G=#G(G>*6-<B@C?$+2DB5-49E69('7:.<<4G?$*9:B@H?!:H053+,:5E34&F9-76<?&'.1%/'!9<"+<<+>*8%(1=2@ECBD:CB
@r5340
GGTTCATTCCTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGNCTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGGAGT
+
A,:?!#'9HH%7#!4$C:;G<92BBA(G=?7'1!-25EE5GD(<D49AA(%73?,+F"?:1:HE)/D$28E0*(F#=-<C3&CE3C"*+6>%(F/GA?-H85)EH;5&B?"*/-83@?C&=+@56BCH?7.D0B/7
@r5341
NANCCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGC
+
!'"+!+))*%'&+''(*'('&'%%#'"%$"&')!"*%)%'(
@r5342
GCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACC
+
/6G6C.+6"3)48'83DH!HC,4H@;C?/+>G2,)G&5!-B9((H<5:%
@r5343
CAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGANCCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGAC
+
H=>$-?-.A<E%D13=D;B(D75B=4E!,;<*(-B:97;7"&C#F6A<45*D>.7#?@.;")=6HECG9C6F#,"!6%&A*9*&D5E/8(.69&B)/?'(?/3153:H#"*@8.,3&$?+#@!0$"-;9=.>/@.E69)G3.C0HC="G0=9C70>6161?.)0%90=&9++#:4+A"*E+1=(E0%7/%H#HCAHH
@r5344
NCCNNTCTNTGANNNNGTNNNANGNNNANTNAANTNNCNTNANTGTCTNCNGNNGTNNTNTANNNNATNGNGNCCTCCNANNCTNNNNTNN
+
$$##!!$#$##""##!#$$!!"$#""!#$$"#"!$"#"""##!$#$"#"$#$""##!"#"#""#$!$""##!!!""#!$""!""#"#!$"!
@r5345
TGAAGTAATATTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGC
+
B>%3DD(%"HBFE*@:*9$?H'6?)5:0FF'H=A+3;%;+%)D5@
@r5346
AATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGGTT
+
'121"B3AC+9DF*+7/4#'66"&F4);!0;87B)(,%7"8$<*#G5@C
@r5347
CCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACNTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGC
+
--GB7E5,66$/B)%<C/05CG:5;('<(6<4F-%(>%8'!2B,E+A8/(7E;E:;.'GHBHE='9H6B'C2)EE%#G91!@7GD4H(1%-)5;''&H/(HB:H;.).$@";0$*@0243&*9,0'&21!
@r5348
CCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTNTCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATC
+
8#*-@FD!)!#8!,:F;5$'(@)A('65!2@3;!/%F=<9A6)%+"$?7=:720=H9H,/$G),(&4=1DA:!+.B:@2?E9F>@3"F.C,9%>%86204?%3&F1H'D@G+%C;3DA7'0A-;!-BHA;%B0>2)B>(@D88.
@r5349
TATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATT
+
E:'<0=9&1EF6A6;@+!B'*HE)@*DC5-H&A4/5&H9=1!?//,'(4-"!">B@(+*$,$@-'!(#=C
@r5350
ATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGANTTATTTTATTGTCTAT
+
+DH@!+AF,(G-,G7='-8@/7$&F1@-@'!G%?0E&C()*45#'<:'BG*GH6
@r5351
GTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATT
+
@G,E=#CC&G"7+=.(-#=:7"++;#D%C'F'*?.D---)#@2+0@GC*E':6%80#7A(%>-.06'+*C0B*GC!"/4('<?!-,(<!A'E4B9E2D)"*;82&'?0
@r5352
TCCCTGGGGTTCGCCGCGTCGCANAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTANGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGT
+
(>B>@:A=<D>85-$<E9H2;5%(A.,(@E96AH39'#%H'(:<<%&&%>4@C>,'303#,BHDH25#1()=%5&3%0@$%<7DD=8+)*.D3$;>:EEB@4'D&$41:0B05'<%?8#%B+B-'=>.DA$GB3:
@r5353
AATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCC
+
A90<?H.+0733:>$8,.(8/C/%%F.%,(;'6C-.=>/D;;8&0=#:7!4
@r5354
ACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAAAGCCGNAGTAGAAGATGGTAGAAATCAAT
+
(*+"+!)&"$&!)'"*%)*%&%%&'&#*))%"&%!(*!"*+$)$*%&)#+!*+)+"'(++!()*%()((*'&!(+)&)+!*'#$*&%#)!%%#!(*+$%"
@r5355
CTATTCTCAGCNAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACNGCGTGNCGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGT
+
-&:CA/11C)5A,$/8#@$#0CE)<3"!"A<:*+GG3>G:=FE;*G6<7*#@%A*(;/<G@0;C%,B!?:'?5+,+1813;-5D'-'#(.756/(,A@
@r5356
NNGAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCT
+
%&!+!$&+$)$&'*"$)%*#)"%!*$%*!#+$&((*+$+$#$!*!)%!%)&&!')++'''("#($"*"('$"!*$!'%&+)'+!$)#(!)+$+"%!$%%()('#$*)&)*&&!#!!*&*$$%*(*%")*$+'%$+%"("%+'+%%+&&"+%"+"&)"'+"
@r5357
AGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAAC
+
.?('$*$:".%5+B;4A:E=G,2C!E;H*=DFA*F1H%8+:!%(%!0,FGG+/&9%>!6H%,(%1:+D,'D"=E"
@r5358
AATGCTGTATTAATCATGCTAGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTNAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAA
+
F7BFB5D1&+$>7#2(.80%E%66!4AD*H*G3+03D5/H;/FF'2""&967F/6@"13!#57+@'AFA"!($;HH3"*F?+"2A2C))"!;DB9H(
@r5359
GCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTA
+
3"$@%<AA6?F/CC<'A/8)44>#F4G%>G"-"F:!*3E!!2&#,3D-04")<"2.5%1%=0'%,B3GCD*G?.8+/!+?EE.5BE?
@r5360
TTNNNGCAGGCGGTNTGTNNGGCGAGCGATGATGCGGAAGGTTACCTGGATTTTTCCAAAGGCAAGATAACCGAATCCCATCTCGGCAAGGGGCTGCTG
+
'&(!!*&(*')'*%)'"%#!*&+)"&)*'#(#&$!%")%#(+")"'$$%+!+""&#&'+*$#+'$!+*&!(+#$!(!$%$#($&"#$)"(+"$%"""!'
@r5361
CCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAA
+
/7@?G>84-,7D/.+#/'H0-;1!?8+)%E<F1,G5=84419,:H'%'%9?=H7*#$(?AGE"F@H;8
@r5362
CGAANGAAATTTAGCTACGCTTTCNAGTTTCANGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTNGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAA
+
1E7G=6%<(;'<5"6-,")+!!?6E!B"9>=>58!713:,('$5)>E%9@60%$=%5&=(++D)A5#%1".8@;'B#6#"(A:G/G:A0DG6#$4C0000-0<C/,$6;"(!"33*B3!$@;%G#4=-;?GE,/+/2A"5/-9500BF.E+C'F5CH@2$%?F+9F9A4DH$+$2&;!H#31AA7#?*&3B2&.>.G6+8.2)'B?A><54,#+@/<@*D$1#H+)0)0A8A@2'35(ACD!=<&(7$BG8
@r5363
NCNNNCAANNAGCGGNNCCGACGNNAAGCGTNTANNNNNCNNNTNCCNNCNACNNNANNTCACNNNANNNNNNN
+
##!$$$#"!!#$!!""#$#$#$!!"$!"###"$""##"$"!!#$"$$!!""#"""!"!#"$$#!!#$"$"!##"
@r5364
AGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCNGTGATTNCGATTCGNCTGTCTCTGCCTAATCCAAACTCTTTACCNGTCCTTGGGNCCCTGTAGCAGTAATATC
+
:-.)7A"B3C,04=+#$=5"8"*F,@,',4140@>&0!H8*712!)A,C3:)=1&AF.5(9%*%"63#<*C<9'E=((&1@-+7?$)"09GHG4(,":6A;/=(B-1--@38G"29>?'6,/$:.
@r5365
AAATCGGTAGCAACTGGAAANCATTCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCANGTTCCTGCATANGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATNATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATA
+
D3&G)80B(@+3;=.380#22:8%6F3$?+:/%-H0"F-*?-E>:4++A)94A<4="?,*:,2,1'//F>):*H9"(=-B0),$1)0>6"D!%-"AF1C@34*(!/6*=0>:!$-/GH)/F'(.5>H"DE:?E+E'&!C496B>94$>4GH3'.E-$/*'07G47/5H*)(1-4-H*&F@%DC)5;7D!D&2!:0F8&26?#&0G=H!012H?43C<<0:$
@r5366
CCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTGCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGNCTCTGTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTNATTAAAATAACCGCAATTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCC
+
&>,*G1386()7&/30"?1#)5)F,'$'?>;4%<4#-+=278C&#!C=0H$$/;7'(0..@GA=75E=<?79*B@*7F>&0#6FDFF(A*A@>?59A9CDF7E4CA*+0,=1*!&F2.FD6@@=@.;9,+F(0H;*'H:?.4)972&E>'<='(%G'"E*45F:(A!*%(>'%+C?FH-';2$E!8+-28-?54;.);.17#'F0.!3;92/A/:(?-"D"/3$C>A2#0A&+<=)70#-9.)2-"HF($(:;(2?D.9,7/H'9C+49?>177/+:H?H:6!H/',%9BAA(6
@r5367
GGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGA
+
'/6"D,*)2831GG.C+05=&#"AC<9D*?//+<+E-52)@"7FF9CB4&&5G5,:C4!+81E83>9H1<15!:
@r5368
ACAGCAANAACNTGGCCTGGTGTCTGTGGGATNTGCTGACCCAT
+
:67=BC965>/'DG)<6??)H@!;H/'H';B$='"<HF/=1!%>
@r5369
TCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCNCAACTCGTGAAAGGTAGGCGGATCC
+
+''+)+)&$&+)*!##!'(#*%))&#&(")!"%'"$))%)"!('"$*#+%&#+$#()+%)"+(%
@r5370
TGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTNCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCG
+
6/AH:?#C$5<:/>-#>($C"<59=(G522%));7D-!+;6#?=D@$+(=#*A8G>==-3G2A@25;H<,"25"%0">>('!21(&9>?1?F<0>4$FAA>#80HD9=,AF'>C?H&=:74D$2E*C42C2-E&
@r5371
GATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAAC
+
FA5$.6*7%%@?6F<4C2>D%-($D&70(167*03*6".":#<'3CG--6@57G657#*"&,DC"0><97#=#/C0F%?HH=+8E3/-21.?#ACD0<D>)=B3.:(:F')**$*<A$>(*-!*
@r5372
NTCCTGCGCGGTATCAGGACGACCAATATCCAGCNCCGCATCCCACA
+
%/D<"1D-+?C!EF%E=A5/"&*/7"9!F%-<)!4>D$%17.G9)6A
@r5373
CGCTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTT
+
BD9CC:C<0()@1!")&(#-<F7F>/'<#)4DB6F7<3DH+-7CE&+F6D>!E0350=*?34#/6/!-!:HC;71+&;&G5<-,4*0.8G
@r5374
CCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGG
+
9D*8+32D+:)>"D79>31;72<,:4"?2A000/,"G:GD"!2/4"D3*",H0H59(B!4B0%FG#;:0.5@7-?,8=BE<=8;-)/8>EE$%7:?G(/H1%65H@+
@r5375
NNACACCNATTGGATTGTTTATTTGTATGCCAAGAGAGTTACANCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGNAATAATTCGTAATCTTTTAGNGTATTCGCGACCCATNGTCNTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTAGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATNAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCNATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCATTAATG
+
#!!)***&+')#&+&'"&!'')!)'##*$!&+%&#$'"'"$$)&!"()%""&("$)**"*+"+#(&"()%"*!!&#&!('#)"'*#(+&$%+("($*)')"!!!"$)!)+$()&%!!*"%#$'"'(%&&!%)*)**"(%%!**!%$+)'%#+"%%*'&%$(%)+#%)%(!!#%#+"#+$(+'%+%*%%)""!$*!*%+)(#(*$)!)''%(!))!*'#*%#'"!+$'$$!*!%()$!$**!$&&"%!)#!")'%#'++"++")+&''!#$++)*&+&$*(&**$%$$$&!)*%$!(+#%'("))!"$#('"!%%*(*!)#%(!)*$+#+!%)&'$"+"&)()!)"+'**)%
@r5376
TAANAGNCNCNAAACATGNCGAAAAACTATATTTCATGCGTTCAGTCTNAAAAGCAATTGGCGCTGATGTAAAC
+
&'$!*'&#!)$+#+#&**$'&)"#!!!#!"#&+()&*%"*('$%"###$%'++(%'*!##*$$!$&#"'#%!$'
@r5377
TTCTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCAT
+
"H>-96(D%E/;*'%%/2;-$A$2;D-21/C<*)3+=3&)?8):15,,%%#'*)73$74H=5$1!*.(H0="1)=7='F$/C2->%'36&6"7F96"H?>'4+=991!EFFHB+4',>*+%=$!,=5@>A/!
@r5378
GGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCCTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTNATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTANCGGACCGAGTTCAGAAATAAATAACGCGGGGCCGGAAGCCACGTCATAGNCGGTTTTACCCCGATGGTC
+
7E&4*E,')-*70EAG?C*+5%F8!F.6>,0D3D0,H(=%0!&@"<8184*.C:-(&&!G>;G>:0+DF24%>!1A??/?BG?%@3%40E#F'7?7/1F%'6FGD'(4'>;7,H6,27-@F$:!>63#$2$D*$,#>F.&(0E&BC5F*16?"F"1<1D(6?265/!)<*D"?=B8)GEG/B0*:H'+&H@13##70GD.(C:$/'>!CAH1'
@r5379
GTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCNGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTGACAGTATTATGTAGTC
+
93<:(E=6C(E4;(,-FE+*4(B@&B#8!;(<D=%48%4#AF.G?1$B#*);H:8DC8%1'E6?(+HAF.?+!,1E+,FG.%AA0FE4(*07E,77"6945:1D1#'B=G2>.G#"HAA:*@H0$.#!4?,6=<!>?H$7@/G'0@?4&3+H'A<#.'5H;!7)E6GC!#E@;!A(E(;').C7AE!9#?)'=%9$'7?D?*9:.<:#/2@2D<<D/:%.4E*E/+*!6:0E@6<(BHG3(08+#/5C:#"
@r5380
CACCGACCTCTGTCAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCANCACCTGTTCAAACTCTGCGCTGAACTCNACACGCAGCATACTGACCCGCGACGACCATT
+
)CCE?==#&'!E=;=A0@$;>6361E0E"/<=G7$;!5A)/EDA+@3)A*#+B*6+:!'44F+3$&5);"&305/)#&H'$HE>FB(&9C.='(DF0>3C)%&>@<'<DD:=57;+(H<3H(@"=2%G3?;#&#E-H=E'F4C)1:"'8)"7B<'7D-G#@=#(
@r5381
CGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCNAATGCCCCCGCCACCATCCC
+
E:)2"C!-H6-$H/H<$@B->;$3?B':AF3>H$**#BB=HC68!/=#&3#>C,5:("F#*%,:>8%GF"+C
@r5382
TCGTCCTGTTCGGAGGGAAGAACGCGCGATGTTCATTCTTCATCACTTTTAATTGATGTAT
+
36H&382<)5:%2/*0D,(D%"EF.1*6F12=E5H'.>:/9(%&$"6E>"H6&%=A0?53?
@r5383
TATATCTGCGAAAAGACCGGGATCTGGACCGGTGATGGCATTCTCTG
+
D9;AGE4HA8?$!*1-%3G8489!@1"H(:0(9(#532$=B$$(:,A
@r5384
GGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAA
+
8(B-;(?F"*D-6,<'5&;-05*.D)7@9/%6D/5AC;'G$&&=#'>$(+C(@*)-"
@r5385
GCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCG
+
B1A,:$./.A-G$E>6#3G'$7-"!B/38--!-G,5@.8?-3=E?"*G%'4?3)E(;)4:2"E$20G/170).(=,FB-
@r5386
AAATCCTGCATGTGGAAAGTCCTACGCTCAAGAGAAGCAATAAATATTATCCGTCCGGATATTGAGACATTCGGTGAGAACTTAGGTGTTTTAACTCGTGAGGT
+
B8H=B8B.)#G</C&*5:3'51BH*$?F"&',:@2732)0,/3?",'3*+->,*D#>>&G3(DE0=F4,(*;,0<$8<9#%D+54F#H61$3"4'.'?(G0%E5
@r5387
GAAAGCCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCNNGTTGCTTCATNCGCGATATCGCAGTCGGCGTCACAG
+
(&&&#)+'))%'*$!*%'*#%(*''(*&#++#($$$$*'+)+"%*&+$#!$+%($&)#++*%$+$$%#'((')&(&)%*$("!"!""+*(*)+!%&%*(
@r5388
GGTGCCGTAGCGCGGATGGGTCAGCATATCCCACAGACACCAGG
+
%#:C2G=(*')(5$1"H.:3"'8!.+H+=-4&@!*;5>F,;"63
@r5389
TGGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGNTCGCGN
+
$!,.5*DD7%6CF(?3D6,9D8<!:8%)F-H4(#4A531.G.+"#1/#!>85,@:?A@C(+=?.07=D&.H52GE/7H?A)1-HC0*%E-C@;1H<'8"4(35)&G9(
@r5390
CNTNGNTTTTGCTACATTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCNTGCA
+
"*(")$%%++"&)%()*'$#!!*&'")%+#&#%+!&(%'!&*(!)()++*(!&%+&*"%$+#*($&%+%'")''+!)
@r5391
GNAANCTCNTGACNTTNNGCNTNNAACTGATTAGCCGCATCGGGCAGGAAGCAGNA
+
)!&$&)(!$%!!(()"%#%%(#'"++$+#%+%))$&!""+%*(+""%#")##*'%+
@r5392
AGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCNCCACATTCACCTCACGNATGT
+
613)GF*+:$=9<!=9,A@GC,9E;0*D*CA16);;<$("E2/AC1H&>21HG%"#05:B3!H$7%!3AH52-$&
@r5393
TNNANNNNTTNGGNNNCCNNTCCCTCTTCCACCTGCTGATCTGCGACTTNTNAACGCNCACAGCTTCC
+
*!'("'*"&%!('(""'($'+$*&$#%'++'$*+((!!'%&*$$#'()+&%(+"!"&#"#&!#$"'+"
@r5394
ATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGNCCGAAAACAGTTCTGGCAAAACCA
+
1E,>*0"1G&,=-7'9)3:+3)H,5F7?"$/,:72>A+.;#2BF@/:&$!D)0-+294&'*DB+++*;0/"7(/3<5"F5B!&@A7"(7A;E8+/()'8,5$555C?:6,7
@r5395
ATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCTAATCCACG
+
D*1F8-''5")>'?&>@'2!64#/5)@:6C?"1%H$80BC0&A"E0AH;#E.&F8
@r5396
AGTGGTTGTAAAAACACCTGACCGNTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGNAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGTTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATNAGAAAAAACAG
+
;BG+6$B%C)1C@B+!$"A)F<@@"-<+#D-C<E':F"AB,<."G8('D1:D*129@$(&F133AG0D20-BF;*((;0-4#@42H>0&C?';5CD>CDB">6G%-HA07'?(*3/23E63:#'2.!H11*=<-1H@#E6HC9D,$'!G.#H,28G/"1FCB<E0#E;*2<EE3+&)=%%>;<$8C>#&$;(7GB"1#!7EA8DA::7"D$+(2&><!1?-A5A0-E;>?F=:#7E>;$>'+.3,*D75%<BE;>H'?-221)$C$:A?->%9!!.&-5F*=&%C6(@>"FD19$F%",#*?7"+D0
@r5397
GTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAAC
+
$%)+'+($%%)&"+##(+)($'$$#!#)$&$#$)*)(&&!$+)&)%!&!$(!&"%(''"'%*"%*()#&$)'!)
@r5398
ATGCGGGAGATCACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGATGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTATGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGC
+
*E1)'GG090&2="><5:8/=0A>D?B.F/1G,'6$&>1E'1-:&14:#/E<;+@434=%1F!"1G"B(%.9.%3A<9*,><(C@6(>BH&AH4E4-2-H'?@7&%$D=G+.>1=;-G3768)3D<?"&"("?7E?/>6$3>!"A>6,6#.''.;&D4@?-:*1"B8840!:98=FGAE*GC**D%B*8.">+4#9G(B>BDD83'?8$:B*/5=$!'8#'E'6(7>B.48"&!"0'6<G33$%5);?<'$5=A@D)2(>81+:"12;7@F:)G5'3"5F651!&;D22B9<*)>'&
@r5399
CTGCAACAGAGGGGGCAGGTGAAGGACTCCTTCGGCGGGATGATCCCCATGT
+
*(+!$'*#$+("()*&(&+!&$(+$+)*%&!)*'%$%*()$&)*#'!!+""'
@r5400
CCATCAACGCCCACNACCGGAACGATGNCATTCTGCTTATCA
+
/$*>?:%#;E/9H-0EE.1"*%G%6E&*#B@#5BA/-$@!,G
@r5401
GTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACG
+
44DH2$G7@)-;%<-#G8#.A(@@:1$*8<H2%'/#!$82/2+:35*.=+"F$'E-#>B7*77><
@r5402
CGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCNTGTCTGACC
+
-&CG*#9#6*A,.%.:9-3+G#.(%/(C5?"85!?-;"*:;/H(5<!(E"<=4C"D1,E4+=F!=4$-4549,G3<&.#=8H!)/G'?-%$&@#;0<
@r5403
CTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATA
+
=-.#9:+&5A(=@:H@44).?"5B*$?&9*!1F-<"H;/,*9.D>E8;"9'3==&
@r5404
CTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTATGGGGGCGATCGTGAGGCAAAG
+
H'G%CE&,%1%((6/$1:D4'EF>,@3(=)/F&4(GHA-3!.;@73F7@.C&.-)G?6,@*E?%E<C?76=8#F>#0.CH#D3-6>+H@&-;9:"'B,$*C@%=*0#=A03,H'E;7-=B-C%(=:F=!>3.3#H7,(1FC)662@&@9/3F@+02<"=.06#<B/0*B?5742'664<;5H("5H*$!9(C<E323E"++40222EH?G'<C"2.H*'5;=E%G,<0*-F,0>440A+"G(4*C<2=/9HE#(6AB*"/2=C>'6'%%<@2%(CB=(G+F72CC8+C80"%-23.=(G$B
@r5405
GNAGGGGCGGCCTCTGACGCTTTCGTGGCCGTGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGC
+
*#*""'+$!*"!("(+)*#(+%$$%%"%&!%&!&'&&(*&&($+%+%+%$%!(!##+&!!"%'("$$!(""%!*($'$*'$%$$+%!($!&!&'&$*"###"+'#(+)$$"%&!"+%%%'&"%"+#(#&')!%(+'+&!&*(!")(*#!&"(%(+!%%#$*!%""%+('#"$$%')+&*)*)&$#&#))%')%$$("$+)
@r5406
GCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTT
+
)HBEF4@0>&311:+//=53,?28C:#8("/59+.)BD-'10FFE)*C(""7,AEC;04<D2!/A(2AD$-<,?@5)"87<;,"(E+=137*E/A&$D:@>6G!')4)E0$&.H.3;65B-1.2H+#5/@5
@r5407
TTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTA
+
.+.%&&/C30G!2#3B"@3E;>'B=@@E5-;7-#>A)C68"8#?!<71?<F6B4#&H@$A?$7H3-,;0;D"E",996,#78>,+$B'2<F=C:0G.'295+(0-!56:"@743?<.H,C%*'2')FHB.2(17@=8A-&=B8G3%%B9:D6--)%C?@)*,><"-DB+<07H0>$@F:B)=#)C>(#(#-G+FC6(7=17),!(1,4&*18?';$E>A4!+@#*<6EFD<@?5H++
@r5408
GTCCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTA
+
*!*+!&*+%"*&&%($("'*#&&%%#%)!'*%)+)#*++'*%"#!&"")#)#("(%%&)%+'&%"!*++$$
@r5409
CAAANTNGAAATCAACCGTAACAAGCAACAGGCAGGCGTGACAGCCAGCAAACCAAAACTCGACTTGACAANCACAGACTGGATTTACGGGGTGGATCCATGAAAAACATCG
+
4DAF$G4E"B*1'D<0*FC69.=4B>"BA#&@-D:A#2F=!#!,)%38)4!HB.-9:A<!.D4A051H9.%F&06*.B31*@=<0#>%'>1898$43=3B'8())=!G5B7:
@r5410
CTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTGCGGAATCGGTAGTAAGCG
+
9%C=1(%?963(+4&(A,)$=G3$*@>6$F!%G:E=;6!7*C7D"A6-?C!?51@#$8+&">B?$C#
@r5411
ATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGG
+
G="3":,@,0:7.:C(=H4G.""BG0A8-(&:87>$C3,+D8G
@r5412
TCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGNCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACC
+
/3D?6?%(F34;$<*/'3-)/*GF,?'$B0F73.=B3:>%;;;+>?+1F011-=0@&0D&9330>'<#=06"/8"$-&:E?HF*B'>!6*4,9.?G
@r5413
TGAGTTCAGCGCAGAGTTNGAACAGGTGGTGAACTGATGCAGGATATCCCGCAGGAAACAC
+
:7FA0))F%C<7G<:-3D+B9?4D:D;4@E0&8G;+G,./<#1G'=E"<$&=>431(F0(,
@r5414
CTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTC
+
/3H!F&$CC&7B2$FG6:6@??A1(>@!C5'F.<9F<*"!13*#$@5HH#@9CC">''E0,"/27)</..G
@r5415
GAGGAGGANAAGAGNGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGNCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCA
+
1-)@@=("1723+4AD8<$>:3061;>7.B?,C@CH;+H2/)4A*'9EH7>G'D6%AH*?G;<8!#C@6*'-/%8AFG+"@<A!"91?@0./A,)*E.5;1F"@.@2%H.D7D:+>#A
@r5416
TGGAGTTCCAGACGATACGTCGAAGTGACNAACTGCGGANTCGGTAGTAAGCGCCGCCTCTTTTCATC
+
BBG1!>12'2#>)/?&,6&1,FE0!/<F".5,G-H9-8H6@60:8"?#13>7%00)7A#.15,*B.H,
@r5417
GTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTT
+
D?:='H'1(*!:>27BEC#D5>67,1%*:)0'<&9DE+A3.<"#
@r5418
ANAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCAATGGGAC
+
)!9A4H==14G-42#3>*'+?@95<%!=.=2(,3$HFE5/1+=#=2?3C>-991-G"$@&FH;*'/2G#%AA8+,<39>8B)";6++535"$.$%7-0?-'
@r5419
TTTCACCGTGCGGGTGATCACTTCCTTCGCCGTCACCGCCTTACCGATACTG
+
-;@-,65272H@,&;!)<D8G;#%1%/C%>6;0"'"8B<.96+.%(>;%(3;
@r5420
CCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCC
+
+("*#!%#+'*('#&$#+%)!+)$"*+#!++&#)(+")*+(''
@r5421
TGCGNTTGNTTGCACGAACCATATGTAAGTATTTCCTTAGATA
+
F7,@C>F1:0-7?2$<*.9;767HE'AD%&48>1!&7!)G?2D
@r5422
GCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGGCATACCATTTTATGACGGCGGCAGAGTCATAAAGCACC
+
%G84$326*01%#>1DC#D>.//%4/@D8)&&E1E$@H*>F:&*GH*C@+2F==%+;GE,A)<4E3E':134-*A&-ECG36H0#F=(9@553GFA-G*0331CE2,5'D%?:EB+?+:B
@r5423
NTNGTTNTGNNGTAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAAAGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAANTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAANCCCCGNTATGACCGTGAAAACGGCCNGCCGCATTCTGGCCGCAGCACCAC
+
$!')$'&&(%%+##"#"$!$*'(*+#$*%*&&#(!)+&!+#'%%*"%'(*$*'%)++$*&'&!+!'++*&"&$#%$!%'&)!&!()')$#("*(%*+*"$#%*+*!$%)')(!'!+$'*#&(#'"*$%%)#(&'+*!"'*%'&'#+"$++"%!%"&+*+)!!+#'$&&$%*+($+$(&!)$"!)(+&#*(&*&")$*$+&)%%!'#+")$#++$!"+$+"#!!(++"(%(($(#%%#%*#+(+*'((*#%&$(*##$("$)+++**#%#+!&#$+)(*#!$((
@r5424
ACCCACTACGACCNGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTC
+
+(&%)$""'$"*+)(+)((&$#')%'(&!"!"*&$$+$+($!)!!'(*)((&)*(!)&'!)!%%
@r5425
ATAATAATGGCCCGGTTTGATATTGATACTNGCGGCTATCCAGTACAGNGCCGTACCAAGTTAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGN
+
;-&5&+A4?A#<F>3/3-H4=)2E-;6<+&9:BEH>+7G%!*@"17=>'.*;822749H142?$"C*:E)>'67E!;<?#G8!#H26"A69-?0C<$?-B)&-4DE.C)7#D8(%*<#'2/:GG<CF5@8=A,"#H93+1$1E78<+.)E6H%6(7#
@r5426
NNCAATTNNCCANCTNNNCNGCNATCNCNGNATTCGNGACCNAGTTCATNNGNGGTGAGAGATGGCCTTTTTCTGATAG
+
!$*)()'!%)#(!'(!""$!**$)'&&(!(#&#(%&()))'#'$$%&)%%")"'"(*))($+"")"'+$'$%)!('!+*
@r5427
CGTTTAGCTGAAACGACATNCATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCNGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTTTGTAGATGAAGGTAGAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGA
+
@/!BDD>+"D3ED>'((/5.;0E219E8@%;/9.:!-:!BA:)B)H42=*;E>:&(>&B)B7+54*(F='/35")D#.FEC"(/EB>&/EC8#4?@->217E4%.8$+38!<;B+&8@65%8)F#,HD:B','<84)@.-/.C&-;F!%9$96<8*E*EC>?!0$@;$C0D+AD?(1>&,E"%-;&,:>DF)3=HHB))(@>382"
@r5428
CACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCNCGC
+
.31H3$2F*C%7#=6.':8."."''"301'.493!4HF><>8F0)<DB:B23>ACB77!$6E>8!<9B0EC;EE!%8-;8$#
@r5429
GCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAANTCCTGCTTTAGCAAG
+
,85@3!9D;?GC@##9$8#.G$%""$=)#=:;!F.+>H0'-<:15%2ACE(9!)6;BGA;6++0"$2/DHEC:2E,C-!C:((,%<(H;2;-F!:5#%<(B8)+@<A&/@G1$3=6/9H
@r5430
GAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCT
+
:+7:=47D2AC;.90D=,4B4:H6'9$0**0G>#5GHE7!D
@r5431
CCAGTCGCAGTTCCCCCAGGCACTGNGGGCTTCCTGAAAACNGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACNGAAACATCTGGCTCGCCTGACGAGATGCGACGAATTTTCGCCGCCCCATAAANTACGCCCACGA
+
5%<::'&B@F<#9"D?<0283$0@G?H3">F&<C)-F!(B'$&*C2-8>*8(?G$22%?@;>CB3/?"9>.G3E?"9A/=/A<A2HG%23GC:<7ED>4;64F)7;*235>3,.&>*/55296+D08.H@,BG7$)+%-;7G7->4!=;;5'BH?('7#65&00>B7G
@r5432
GTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGATTTCCGACGGA
+
8D#9G".->%,A;CD0+<'61?4D5-40(C&0:=0@<C;=;,A"@.072$07/@.,60.0E.=+&99*:+&'5$2-"$2)%"F9
@r5433
GGGAAAGGCTGACCGGCTGGATTGGTGAANTTGCCGCGTATTACGCCGCAGCGTCGGTNCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACT
+
<$7#9:<.3#!'!9H>4+$/'/FH%1;:9EC::2%CE,A92)+B'7C3<='H$(-)A*-<5?:/D67F!>6.C+'<08:9A5,.2=5"8@"7!<A8>-2+/B-<B>
@r5434
TACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGNCATCCAGCANCGAGGTTTCTTCCTTCGTTGCNA
+
(<0)%="G&7'&%=DC8)8C5H%ED/?$$1,<(?=A8&F'G(0+<+:E;1&.9&=/H=4=3.HH@AG>F"1.1:32';;#@5-D9+*;6>C?3F/2=77$3;3B#8H-25HH.-*A.?E=/1%$*()&$$55",H0/"E75A?;<9;=0D"3G
@r5435
NAGTCCATCCGTGGCTCCACGCCAAAANTGAGAGGCCCCTGTCAGATTGAGCGTGCAGCCAGNGA
+
!A/H:'.6F#5!.:%=3>;B67!>'H&H)=>>G;1"4!#0=#966BEAG5H+=H+1!GD.'1.D%
@r5436
TGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCG
+
C)3'@:62;82?FB8!>&$,2<3/12,G;;3:<7(!+!9D!)+377+@@*&D)C:A=:)97!)'H4;C%071>!$>>-<G=*
@r5437
TGNCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCNGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTT
+
9<;!!8HBD*=$/2;F?C&F!-888:D+)3>%G4=DA3B6F7/3D,B@5>>=6/"+(D':"&7"E;@F6!!"/7&52?*)461),/,5DA4AF18:H%C76)*<5@<,1!/;)3$$?&6)+@-25"+8240=6;3ECF07.01,.*+!7B4E<@
@r5438
GAACTGANGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGNGATATTGCTGCGCTCGA
+
1D:,HB=;:.-."FG2:.#3670!H7/4B+>)=FB6F,6C4-D2#F<-=$B/%>&;)&0:G6H:>E29
@r5439
GCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGC
+
>2&1'=+C-H<-&G?>C'%98BA2?FHB*29:,"+>'-=@0GDF3'#(
@r5440
GGNCCATAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATNAGCANATCATCTTCAGGCTCTTCGTCAGCCT
+
67F7//1>>("+2BC'+.%@:E$>1@9'?9B1"F1E'9>'6/./5%H>,779++1,761<,>>71)C+&69';4@=
@r5441
TCAATTTTGACAGCCCACATGGCATTCCACTTATCACTGGCATCCTTCCACTCTTTCGAAAACNCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGA
+
0$AA0-),(?16-/H<&4?8?19,<=D/C(*%F<D(9=$)6,?0C4*B&;3?$">)7-(=9.4A:+AEE&A1)5;<@+592FC&3CE"6>7>01AC8161
@r5442
GCGGGTTTATCGGCTACATCGGTACTGNCTCGATTGGTTCGCTTATCAAACGCTTCGCTGCTAAAAATGCCGGAGTAGAAGATGGTAGAAATCAATAATC
+
58+?H"04@(%@#6AH(A4>EB5FA24'D%,%708(6#D6)"*C$B,E3G:@)E2>&4A&D)9D+D<(0A=:,>1$1H<0!'*80-D&*/5<#7D88"!;
@r5443
AAGCCANTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCAT
+
)6F#06#F+3=@,F6!(G-H"&">9$"#B+'FD*40,:+@76EG*)7D)(>3CC495HE718=B!3B49!.D63$;!$%
@r5444
TATTAATCATGCTGGCGCAACANGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGNAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATNAGAATTACCGATATCGATNCATCAGGAATA
+
&+:)@(/G/'#/78+GD>))F*21E%D)!74,17G*$2-&(!0@2F5;(/F%A3B!-#.&=%5<"):1&.<7&&.A#8?)=%'H$++?,'58??&;7A7,5$B+;G-=-C$7-("D@"9!D$D-&:',;7<6)91B8#$$<<1/>BB4>*3$5G'9>-@&5+55@6+=C,@$
@r5445
CAGCNTTNNNNGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCNGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTCGCCGAGGATGACTGCTGCTGCATTGACATTGAGCGAAAACG
+
*&('!"!#%!"(+!#($$)'$$**&)+$"'&"#'&&(!*)%&'(#)&&**)($'"#(+&)*)%+&)+$+$"+")$%&+#++*")##++&"+*##(&('()(++*%*!'#$+!#)*'#'&#"$)#)%&'")$'#%++#!#$%+!$")+#&#&'$!"*%'*$)'+'%"('**"#!
@r5446
TAAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTATGTG
+
(%%&*%+$$*+'%#)&*!%!%*%("("$%#%)&#(&"&#")&$%&!)%+$#))&*(*&))&*'"!+!$($(#*")%%()+)%#'"+"(#&$#'("&(("+*"+$)+*"!#&"$'#!##('!()"+
@r5447
GCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATAGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCANCGGTGCTNTTAACAAGTTCATCAGCCAGTCCGNCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACANCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGT
+
*D>54B@7794FE0.E1H$"'1HA*<3+&3F;2;)H80''F"D45%93.+,FGCE=/37"F-2:<'%,*=2;DFG,=((2.B>4G<;,,G?1*2@.)"D84$'<7-6%0++6D#E-1'286,C;D9-()533ACCF?H;:>(.71<3(HA3A>&*B//A+8==)D1E-8+>:!BE?3$&-B4>;?11&=D0+1*$3<HBG'A4G=46=B$7;E7(?!G+&*5$!HH,(,!@@2)<>D%*+,,E77F,9'9;/.8%0+66#*)0;*B=(>24&''<)8G1$/0D-)H8#F>3-;(526+GG.>'-
@r5448
ATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACANTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGT
+
$951<<G6383==6.DF,/7=$,3',39*#;%/*C5!0>DA--+>:A,&<70B"450'?B4%$0G2D'.7D/0=F6-E)BEE?1<A;<!H//'0;D=,+<8???*=5*0E><8")3;$8H(D;HF86E?GA2F;%?).@?94B>8FD531?@=8911D"18,1<!6;,<=A1B)299<
@r5449
ATCTGGTCTGACCTCCTTGGGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTNGCGTAACAAAGTGCGGTCCTGCNGGCATTCTGGAGGGAAATACAACCGAC
+
;;F185=#,7.&1@<%AC48/HH2*3;>3A)&B<AD/H;,.:)&'B)02'9,G73%:3E),3"D8G4.$C<DCD;5=,"421;"F?"+?0"7C=2G9F;=.%0=48&76E;&F325'>!C#.&B,9+
@r5450
TCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTG
+
<7B!5GB>G)<=./.7BE*62*G2@<(1%:D46.:&F,C?9
@r5451
TTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCG
+
3E",!&;E:0<><@1BF*0:0G@8>&;?DFG-@#DE+FB9,?2(B+?@"6/$02?58*1&$H(
@r5452
AATCGTCGGGGACATTGTAAAGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCAGGTACCTGTACTGTCACCGT
+
>#'>B(%"F?41+9C@-H+H3>"6:5#+<G&:@+@%7@.;">*3.@D2B:6FEA2#4)97C)6;7&=>3FG671.:50(48%(!!&)E5*.5<<:?
@r5453
CTTCCTGAACTTCTTTCAGACCATCGATGGCCACACGACCGGAGNCTATCCAGTC
+
:",?=B9#!4AA>5&-+<;#A?::66,4"4&,8-)!17=4.A<6?6173B2A!+A
@r5454
GTTGATTCTCGCTGTCAGAGGNTTGTGTTTGTGTCCTGAACATAACTCAATGTTGGCCTGTATAGCTTCANTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGTCCTTGGGTCCCTGTAGCAGTAATATCCATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTA
+
(FAC045-/HD4/7A@;D7B>:F-0:79>@+1A24$0(>/'--,C3#0)>-A/5$$<!@=5F/9<?.&D'@5.3H@9,0?/:@1'>=+:6$-')6>$0>9?077*8A1(!EG'A(,:'3G#!<0?(&A#,.<#5D:#0'1?AF8:$??,8:8667&?/9((DFD(=(B@:D@$+($"91%9;5!#,H/2::0E6BF%3%':&/*!36("3/8):"/F)5E,%2.6.H+05G#30"'*6*,E:.D*883-
@r5455
TGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGT
+
?3,;H,!-FD0616=,C.GD3&>85#B:9',:4&).&A6/?&%9B?4B<5%?B/>&-(DH@2"#/DGHA.E5333AA,-73=F9?88!?,
@r5456
GNGAACGTCNCGCAGAGAAACAGGCTCAATGNAAAGCAGCAAATCCCCTGTTGGTTGGGGT
+
#')1BG+'80$$)D'.%7>=-#03%.E2G'@-0G,;0%9',#2$,.E30%5.'E5'4>&"E
@r5457
AGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGA
+
;/H8<B7&E31CA3/"?F2G6@<397$-$D@3>$3%(?60,,21"H@
@r5458
TGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGACGTATGCCGCATTGCAC
+
G:>"$HEG9'2-78#<:B94$>)59"@5-2E=-7=24*@(+C#<@+9B7!#-)@0A
@r5459
NTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACT
+
#$G&7CF008:0;6*33)=-;E;0/,B5E:>B<B<2BCB#)$HG50G:*%92C89ADG5<""E)/0%55.H$82,$5.$$GB7.EA@:<
@r5460
GCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTNGTTTAATCCAGTAACTGCGGGGCTTTAAGGCGAGNTTTCGAATCTTAAGTTTATCTTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCC
+
&=<=)?.;+@-A!>0%-.@!">AHC8-#'7DH!035&)6$'2:B8.:G8CH.">,HDF(.?.F?5D.E9F29/C)A&6B1>#<//F6#F!G/#<-$E89$#"(AF"+2D!BF-3=420=/<.B..%"0!2>(@H=+"GA:G1@/%DH2
@r5461
ATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGG
+
'*#&+%#+&*"!$"$*!%%'))#"%*%)'""')'(+%+(+#'"'"*!(*+"!#))*+*#$&("!%$")+&)"$%!*'""!(()!$*%#!')'%&(%'%++%'+)#""+"+
@r5462
CNTTTTNGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTAGTCGCTGCACATCGCATTCAT
+
#!)($&$(+!$%%+'+)#'(&**%*"!+$*+)$"&(#(*("&!'))"%$+*'#+&"&#$(%%&$'#&&+)&%'&'
@r5463
CGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCNGCAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATANCGCCCGTCAGGAAGAACTGAACAAGGCACTGNAAGACGGNAAAATACTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGCAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTGCT
+
@+AC+BD),/,%$9D6?H(&1<;8"?:D4);!D5D>+;&,%4<)+(3A%))=:8B%#))$'8-*.?CC34>&7,)A?2&)=-779)()%,A>7B#+32!#,!3$FEF3?25@05(*$E:8;;'7?57"C:2A?A1B'@%F#7G6D07ECF>(FB'@+6260H.F.A+.;*01%0E*H2C7(#()@'B:=$=FF"B(8E&G<;C5D/*A?+2$=<B<(/D*8)"/D99*EHA:@@E"-:A!4+F--674#;:&?CB0%9
@r5464
TTATTACCATCCTCAGTTNATGCTGCAGCGCATAGCCCAG
+
.!68G>@D)):!#(!=B);=>1219729DADE/G&'789D
@r5465
GNNCNTNGGTGACAAGCGTATTGAAGNCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAG
+
)!#*!*!$#&*+%#!"(#(+%!'&(+$&((*#*%*")+&'("+*)&%++%!"&%))##"##(!!%%+$&)**
@r5466
GCGACCAGTTTGCTCAACATCTTCTCGGGCATAAGTCTGACACCATGGCATCACAGTATCGTGNTGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGC
+
)')*)#)+&&#*+#($#'+)*$#""($!*"($$*+#'+*(!*%")!'(!$!"'#(*&*+"%''$&&!%#+)&*)+*&%"#$%$%$!%&$"))*!"'""!&$!(%"%*"(($++''$("!&++''!"++)&+$#%!('*)#&)"%##!)+#+!)+$#)(!(#$+###($&%+(')"%'%((#(*((()(*'+&
@r5467
NNNNCGCATATACCGGCCTGTCCGTGCAGGCTGTGCTGGATCCCGAGGCTCCAGTGTACAGCGGTCAGGAGGCCAT
+
!!&!))(+$+)+(%"!("+("*&!(&%*"!#%"%'%(*(*)*+"*$*)$%$))!*+#&)$$&('*(#'%"#!+'"*
@r5468
GCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACC
+
'E<D1,''5(6G2(3-H9B:<#@5A159=3="F;HA!0"C:1/!E#11#''.0!&BF/<E*H%5B%G.,$EA3!/FB)"6
@r5469
ACAGACAGAATCAGCGATTCTGGCAAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGC
+
4$23!4A+EC%>5?.6,?>>BF7D4!9'4@EB+@*H*H;35B(.$8($B%1)F$;0*18*=9(6AEGB4E,D2);G3$C7.G))%7DB>!A3'?F#B41B@#D7D??+EE#.-6(<5!+H%4=DCH8&'0/-G&.)=266$5C(),<"5">C1"H2+A6:G*D8#>B8G*;7A"F;88>6B.*364)(;853&<78>.-+,;+FC7+<>F1B3'3G6#"6=EG/*
@r5470
TGAACTGATTGACCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCT
+
A)7B3AB(1E=;E-;0+F,7!-2620(34+"!1&*$H(/A'G&'#C$A#.<>H16,A8.6,H5AF)/>72#/&6G1<7;H8B3A
@r5471
NCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAGAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGNTCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAA
+
"=B4E<BED,D-2+GFEBFF?)F(9,EE=1";48.4>7H.F)$C2!?54337>=9!E$*2C&>/D&;;+E>)&D0==27?(59711)%E<@6GC85?:G@(DB@/0H1<&48@@!B2<3/.(@<.6!)C3:#8/1G0B&$%,:*028<$400;B1D-"!3F9=CA3F.>;"78CA'=<-<FC9GC?!"4A#.4G%.9<H68*D+*,$#5/8C+,>H6#-!E&70CG#62$51&3"4EDA,1)227-4:A610.)<@'!8??%?>#A,"22B0##9,A)>",;B";G;E>'E5E59=-(00
@r5472
GTCCGGCACTGACCGGAACGCCAACAGNACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAANGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCGNGTAAACAACCGAAGAATNCGACACTGACGGCGCNGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAA
+
+61,B*!=/!6-G-0#+>%?D#(=4E&/4&:E/":#1.5%<H8!'FEA32G0"6=.#8F'A>2(0,(%.?'!#%AF?06CF0B?'?<A";>,$G185?6H5A!)<7<<>EH!6G.E$431&;3@/<<6,>:)D(D>)3&),,2D4A-@%-4D.='D@G=?-!C<BH6,G%B+$-48=<2"HC/3=C@8>+:?</H?-@'>.;!#40#*#(';9?1C)%!1%,-C=37CGED#.;C0?.?1!-0=.,9+5=2"B-CE4,;!#6304'(D27+5>:9@H&D51H=-
@r5473
GGTCGCCACCGCCAGCGAGGTGGCCCCCTCCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGNAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCC
+
>E*-B>DE,)(&.9#%!CFA=)>(@;('0$+7=)8$&F2&#%,)6/>):"12H(G895$<?73+3;5E$.@F>/'0>#.>7'3B.0-'B;.A8H5G:@1D!.:0=B'7F&>85(<3-@&A/*9#H-22D<)2B3>7$)G;04D,D$/84C)>D3@'>;EB0,FE'(=@7D<F?=<"B=7F;#'ADC=EE13;&(9::C0:?!8!A;B".?(>/7.<-&#(4!."/5/EC</D+&C69$5<3=&#1.7/$<2?:#(.74!$;@C-AF-:-?.FEG
@r5474
TNAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTTGACATGCCAGCGGGTCAGGGAAACGTGATCNTGACCCTGTTCACGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGC
+
%#6%.C%HA1=4#2%6<.:257<1<)53.8?)D;1-*"0H;F!4;+0>HG(73<A-),GCD#,A7(E3?";65<D8'1;:#7?)*0;09;=D->$@'E7H@'!@3"9DD#6DC5/!1@=GH;5D+;/=:#-AG&3@)4>7*B4#:B$$"2+/,&B@/
@r5475
TGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGNTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCA
+
G*)'A+EG)D<+EC3!$44B(3&"A$+.4?D((%#9/4F>><50!$?)1)A15.$!@7!7<6C+%0@-@4@+*H;<$A@/E1/2@39D,@*AB9(#.(>+=/>65:D;284:F979+&.#*B0E1.2-H,;!.A*F0%E@B06G.$</-!
@r5476
NGNGGANANNTNCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCANCACCTGTTCAAACTCTGCGCTGAACTC
+
%##%'%#*!$%))+$%&)+)#%('($#'%#+)'($((!&$"'*&'%(&)++&"%"))!)*(!"!*))(%%%!'*!##&**!(!$%(&*)()$
@r5477
CAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACNCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCC
+
)A;0)(=#C&E.)D!A=G"H6+'<?#/-*-+%-313/C1B",.>/*+E/CD=3.%<!44.8!$'64?0A!EGEG;"(*(8%?E
@r5478
TAAGNNACNGNNAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAG
+
%*%($$&(!)!!+'"##(+""!*'))#*)$!'"(&$"$')(*$'%)#")($!)#*(#
@r5479
GNTGANNCTGGTGANTGGNNCANAANATNGNANGNCCNNGGTATGNNGNNAGGNNANNANGTGNNATAGNNNCCCTGAGTNATCGCNNGCNNANGANTACCANCNNNNATAANGNNNTNC
+
"!!#"""#!"$!"$$###"#$$"!!$$#!!!"!"#$""!#####!""#$!$#$##!!!"!!"$$!$!$!!#"$!##"!!#$$$#!#!!$#""#""!!!"!"#""$$!!!$"#"$$!!!"#
@r5480
CCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATCGTTTTAATTATTCCCGGACACTCCCGCAGAGAAGCTCCCCGT
+
*)&7$:2./4@E7'@/?)08<*"F5.(*0"4B9>'C@?+&>4<H9D!7:-.-=-3>834%G@D8*C1,3&?C+FD.:>/&'+59#H<!$"*,'9CH>A%.99!H<1:8C%5(%?B9542,H8886.#F3&257-
@r5481
CAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATNTCGGTAAGGTAAACCCCGATTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTNTCCGTAG
+
=#%@5?&7*1F9?C.="=35;B3(?7+!G43F:D,F&GEA;+'/#>501FB1'6(-FG;E)?.A+++1'3D;"%!;H%&#=H?+&4'+C(0?!$=AA+DA#@?5"%4)D):)3D-A,*=EBA*87+EB.:)BG(-(%(!F&8),?,?H>4!G3H?.583@,&0!%>=;B!),7!'
@r5482
GGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATT
+
=G8A,=%:#@/*6-0;BD68H=>=G:9,<%4$D@C(61%,.-9%8#@2D7653%E/?4)4+"(#E??<"F>?.1@70$<0%#F=+7&')=6,'H.H
@r5483
TTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGNGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTNCCATGTGATACGANGGCGCGTAG
+
G:;8"@..53021>,":,E<(E$-6>EA$;.;4)%&+1!-%G$*"'F<5B,&!C6#?2-,,A88C;2-;8/AF7(H%92#85"!(4D&(G:/3F-;%-4655$"G?F@B%!/&-!G8%?B?E+D-?71HB*@$=D(F-54%,5BE,(%806'77*$%!80/-1C&)=*:->:AE5A13CD69??G6(!D&
@r5484
GGAGACGAGCNNTNTNGCTCAGCNTCAATGCNGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCNTCCCCGATGC
+
)!%"'**&$$&!(&!%+(#$)*+)!!+&+)%((%)"()'!*(($+"&$%')"#!%%'(+"##"$%%)()*!%(&'%+%!$%*&""))'+&!)(**+($'$$+#($!&*!&+'
@r5485
GATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAG
+
;=9+@=;H/?::+.G5&B,*'E1-6.+G5EF&1:&25*F1,543F:><H8%
@r5486
NTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCNCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTNTACCAAGTTT
+
,5B"AH8BC%/%>8A;,6=60;F.F7.+H&9*."E("C$:B3:B/8"":')CF*9.A,&!4(GF3&'*EH:H;&H()'(#9DF.:C$++D?08-"%A,718G6%;,G;2'2!.G%01AG%:D=E;4H/B,:E@GH%-D2"/+G$
@r5487
GATCNGATGGCCACGGGATCGGCGCACCTGCCGGNAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGNCAGAATATCCCTGCCAACCNGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGNCGTGGAAAG
+
'')(!+*$&'&!*$$%#+$&++#'!"#&((%"(#(!+)#(%+$)'+%('+()!*$"')*"%&&'')!!"")"%')%#%*+""")$*($)%"'$%!'$&(#%))%&#'"()$'#+"'%&'(((%%"$'$$)'%&!*+'%'"+*#%)#%#'"+%+''*"%&#%*!%!(!'##"$*"'%+)!*(''+
@r5488
AGTTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTANCTGG
+
)A.A);@7D';?B==*B(*F5'F+7EB8-9A-*%5?2'5F0%EC78F=A2A*((24?E<
@r5489
CCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCANTGGCAGTGTGAATGCGAACTCNGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGG
+
:,'$C/@;?>2.;"=.(;20FFA9/?H1AE"4:$E&'!-:)<8@6;;%42-@F)B#%0C$6=5B4)=5>$(-99+"</&9"/C"4##:77BF+9#:=7+0H.:7EB*3&,%1E;E-FC<=2(G4,DA3D100*-G2!.;:7;#"9;!3E/D2F
@r5490
NAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAANTTA
+
-A"2%D58&D52#(4G<2"6'16:%./);.,7<C"G)FB1?B72=2
@r5491
GGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGCTGATTTCACAT
+
4D0>%*6G35F7)//=8&2492=;>!<,H"5<02>.A?=AD%-BAH4C$3;7D"?1*F'6H1"*<C@024AE&>?
@r5492
CTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAANGAAACGACAGGTGCTGAAAGCGAGGCTNTTTGNCCTCTGTCGTTT
+
-;??>0A$2@90D4'B>0.4C0;#?F7698"%-81D1@EC;4"C1D;(!62.3*2BA/(<@>4?F*HH5.E*9@.#9?H3E9=A%-F9A:G<<%?,8F39;)+8,/)9=3$&54'!0CG)!$D?$A(DB:40?3H
@r5493
GAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTAC
+
@(:>")AF&4?<>33/'+$$<8+F1'B&$*.+5%'4>H#*5"'==9?8(A0@G#6(4:
@r5494
CTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCA
+
>>2!>)F+,=79->!(29$'A*C!(GA")!8$==G*$,BC?',2;D3)>E86C342!6
@r5495
GCTCACAGTCGGTGGTCCGGCAGTACAATGGCTTACCGTAAGACGG
+
,'()EE'D+;='202"*,28%.0A,-*6E*;&!("&<)".=#-C!'
@r5496
GCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGA
+
;3D9D835=!H"H$<#*0/A-/?/4'E+!)G&##&E4$/5,$!&!847=7%"$8<:/G'4+&(!E<A.'?01.0&
@r5497
TGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATC
+
HB?--(+;08#=1(,G13!8,B)/28%*41H+4;*0&13/?5;&
@r5498
NGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCC
+
#4==CHD@5,G0H)7CED>,94G/;&:>%D#HG?8=')+4F8%=(.?99H(?,-%?D)4#.<C;7:'?-D:-*5<*$9.7>8)H'!);.'D28<<;?#'*;5;%<?H$7<$6CHG1=0446F47
@r5499
GGCTTCGCTCACTGTTCAGNCCGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGAAAGAATCCGCATACCAG
+
C#$>(9!G"#2#4<4*B1</4:,=-$+.148/-=</'H('(")<9'&F:HA.*:9B>,@6-:=DG6&819>C2+(0#G;&>$("?*.-0
@r5500
NTCAACCGCCCTATTCTCTCGCTGAATCGCAANCNGAAATCACGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACG
+
2>@<1,!0%>FD3.#C7%FA>1/2+</F!(9F-E9B/BA62.D>,@7<.B=5$5&=/6*?&.)'B0($1)%C4-+)>&*:!<):=/&-7@%03430(D9,.*64''=:8+G/<+?);0?.A=5'
@r5501
TCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAANCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCNCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATGATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGNTCGGTTGCCGCNGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCAA
+
E;E3,)$&("$6,A$BH/&$)"1,=GDD.46@&'9#CG!H%0)-A==?E,<;DA$(?#&%(>1G8G%9D@ABB'.'90>8(!$4;C=1<#B44HG-%-<+#D<A@D:#4D,(/9(";B(&05B4?C,,;A"C263<5D$@,59?)39#5&G6A(C?FA"'HDH31%-'874C3*$16;-?<-':F""G3<1AE>+:;8.)D58%8#.,GF-+2$<=@#4>99.H6;)>GE6B4G2@DE7GD/G$0D#(HE:0$7+,/D7*HG3CDD8+H;!.82GG=A(A''92&6);+9';A/+*@4
@r5502
TGCCTCCAAANGATACCTATTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGNGAAAACTTG
+
<7,$>(DD*H/"$,'6F0&@0B%>"+,(';(,"$%D6!)22:?-F/:#$*%A.!.E6&@20G=0G8,93<"7%H,!2(66/F971C<9".17)"',-(F58*A*<9=3"GFA.=!@).D#7;4>8&,@=*0E:G@6E<=C<D5.83)1#384(?0/%-0<8E3?%*@8H0$D=E>+</A,$)H;2.)G%GF9%*7(%"*,H;"GB:*@5#&%G2&8CD=-4#
@r5503
CGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAANGCGACGCAATGAGGCAC
+
.;".@--'?+H7B4;,<'%*F.2(11+&9!F&'?%B+!5">9>%0C-FG1'9?B?'+A0=E'F2#F;>8#=>"C*2<A<<1CC<=A0!D<4-9A;2?+2::&F.BG+C+3:D!)>B$
@r5504
TACGTTGCAGGTTGCTTTCAATCAGTTTGTGGTATTGAGCCAGCACTGTAAGGNCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTT
+
++$*('0D.24C4.A,5",/A=&*?-@5'!GC#(HB"CB=7B'"@8H@78#>8D;&D6(?B,'6*A73<<9'@@'<2"30(0GH=)5;@2GG*;D,<628;"/85A"44>--E.1(58:;E'G-$'/D?B(,8
@r5505
CTGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATANGACTGCGAGAATTAACCGTGGTG
+
4D5,9,(3<A7---F3!?@!=FB(#3&39@(6E&3"'#B1DD8,+3D!#B#G@;)G3C6C40!*BF4B3HA&:8(A*(&3"$G.<)805;5+(!&4D(72A:H!;7!<.!*=60E,31G11@1+#8H"0.,-@FA/A'725)3E1#HHF65&,6'/
@r5506
GCCTGCCGTTAACNGTCGCCGCTGAAAGGGGGATGTATGGCCATAAANGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCNCCGCTATGGCCATTAACCGCGTNGNTTCATCCGCCATATCGCAGTCGGCGTCACAGGTTGCCCGNGAGACAAA
+
+4DFH)@C%,>>>H3!&B*7H"D"/*E'C228(:%#E@"6%E)30+#G":#(0+C!>;0/(#6GH5G4@(7,0HAFF+HD$4&#G%8%*5.2?1/B/,89H:196.*G$$0C!$-&'<;B%5/A,&0-H9-:CB!/CC&..?F&9&F'H?/29=/$):7/-:CF-@G-A3$505D"8F;'9G
@r5507
GTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCAGCTAT
+
0D$""5D2F'DG?"E;>@"GH0#=-/%57C,?99B;5624BF7@DA"/>+)+7EF.>#*3=%,C="-<(
@r5508
GTGATGACCTCATTAAAAACACGCTGCAATCCCACCTCATCTTTGCAGGCAAGTCCGATTTTTTGNGTTGATTTTTTAATG
+
.7$$5>3>2=1?%>+@)H26?+FD3'(13@/D:F36.2?'@%;%9/&318*.6,='3>"2;=B%)*0$%$9>8)2"!-9%!
@r5509
CGACCAGAACACCTTGCCGATCAGCNNAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTNCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAA
+
D=8,/?>*0B89!/=7:&9,48:$B##!<8;2".2G)E4$%/E6=@$$";.#-8#>=9%CFC<>F%1@1;;C%3<+>>;<EG.$!9?1.<D8(HG21?9A#/2,G3*E587<=<B7,'5&3=!D$
@r5510
CANCANCNGGTGCTTCCTGCAGGCNCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGA
+
$'))(!(()%"+&**++'!)!+'$"+'$"(")!&&+((+*+")")!')&")&'"")%$+&($)*%&'*"
@r5511
AGCGGAACGGAGCGCCNCTGCCGCGGCAGACGCAAAGACAGCGGCGGCGGGGAGTGCGT
+
=D2C"8@F$B?5G(6C@*5!HFBCFG#E<!%"4A+&$0,5H7-C4+<B!&=9*3"94>2
@r5512
GTAGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTNTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACATAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATNTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCC
+
*@:..8)*0%E88G&/<<B;H:E*.DAH64/'5<0&1C>2@0?=-<G-075*"&!>!)9!C,71@4!>=%0%*B81B?1'28E@6'>)4!9=7G5,!#741A->B*>:&*$';C<11DG"HD@$*<(4;D+-E)@=E7A."6A6,4.:&GBH#DG0#6>=!8-E2@ED&$@:*%6?<;H/;0"$:!4-86#%B=51#F4<=E#/7-6-71*E!D@@EC;B?4;,!7E*+E12!1;$2D$#518*7?'E7/$A3*5(5,3/@B&-5385'86E(
@r5513
ACANGNNTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTG
+
#)%*#!$+#)!&#'&#(##')*(+%#)+'"#$))&('%'(+!(%&*+!'*%%!")$$**("##!%'!$!%+&+$%"'+"%!(*%%+&"$'%(###+(&+#"$#%*$#'!)(%#$)&'!%
@r5514
NCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGT
+
!D*D$!0"-0'57A1%:*:#2@:,=A;G<(H)C!6%"0#27C
@r5515
NTANGATNNCCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCG
+
($$#)('$!*))'#+"%!*'%#*'""&&'%!(*()*"$)"!#*"+&(*%"+"+&)*')#!'!(&&$&&"$"*%#'$'()*%%(%!!#'*
@r5516
AACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCA
+
@0(61?-22B%>&<%C8=;E.:<8D<?$8<.GA4!#0DHH=:2'/,3H(E<=66<,D7=H+?>8B9E'C#-5-(>3F=2/(<:E>":";;G+?B1
@r5517
ANAGGCTCNCCGGGATAGTTGCCAGTAACNGGCTGAACACACCGTTGATGATCTGCGCTACCTGCTGNACCTGCGGCTTTTCGTCGTACTGTTCCGGCAT
+
*!+%!'%"*)!$*#)!'"+(%!*%)$'(+!'!%(+%"#&*&%!!'*+"(!&!#'%"$*")((+)*+)($*(%'%!(#!(&)$*$+(+'!+&%'+%)%(*)
@r5518
AGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGNCCCNGCTGTTGCAGCAGGATCA
+
-F38;4D?GC@#%,*@0>!'C3F#$*/'9<-5&.H-D@?HC$9.9+D.+)83@-::$?$88:)&(@6!(E
@r5519
GCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACNGCAGAAGTCACTGCAGACAGCGGNGAATATCAGGTGCTGGCG
+
5A(-*H7"1GD+7;/*6:1H@&G-3;#@E,.HE1A%EC0204,'1+F=2(A;.7+=..G?.,3>G#;!4=&H7=99C>%:)-32EA??,362*=04-+%H:50#D0+D'2=(D%+B6:5+)>,!EEC$33%'D0'%7;A->#2'36A-6D#+30<&
@r5520
TTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCNGACAGATTTTTTAATCG
+
'5@'/20A5D43C#6((;A<-7FB%F?7<C5--4!5E1*<')""2D.+@7$7@#H>'=E"
@r5521
AATATCTTGTTTAAACGCCGTGGTACAGCGGCGCCGCCATCGGGATTTTCA
+
;$7*@#+;,0;&)#!:@;2:!B6&B/@.A!+4;$,D9%D@E2BG!!)(0&>
@r5522
GTAGCAATTTCAAGAGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGANGGATGGCCTCCAATGGATGGTAGC
+
!+#&%*("&)$$(++""+'##&*#!'$*)#$''%&+$##+%#')%(*)$"(+'$(+')''($%$(!*""%%*"#!&"#%!&&(+*+*(&$!&(!*(%')#+
@r5523
TACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGNGATCGCCGTCATGCGTGCTGCACTGGATGCACG
+
#+%&!((('&*+$""*&"+%$%(*%%"*)"'$+)%+#'*()+!$#)))+%)(&+%)##'**!$*!")#*(&%'%#'&&##()+)*'*'(&"#"$+
@r5524
TAAACAGACCAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGGCGGCTTACAATGTATAAATA
+
3AC01:,.0)55%&9C3&G!A'$%@"#8%(C$9H!3B=&,3?DCG");E**=$2DE185,G2(5
@r5525
CGCTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACGTTTGGCGTGGAA
+
"#+!#)#$""*)"%%%"$($&%&&&((&$&#"$#)&""!)""+$'+')$!
@r5526
NNAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGACTT
+
!%((C@*06*0+$,#?5"$6("-+&*F>A'6?:CB%32!-E)GG)?,/#/DG7=)/A/=;C(,34C'.2G#58=6D0$9"6:4EF-
@r5527
GGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGTCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGTAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTC
+
,%36$B<!#/D'+0:7<D(E:>"C#&%GG>DC.E<%E+A4G90CB'F*2HD4<#!&'>FB/:A)&F/B::@',3?#$%:,:G;-5H8-*2;C&DA5"!>=*!%:E.CA%(*D5F/%.7@)&$A=<8?
@r5528
GNTTAAAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGA
+
(!%")$(%*+$""$"#!!+((+"+!"##$&(*)(!&+)")%')((*#&+"%(&)!''+""$+'"%#)!++)%+*#&'!"""%(!)&&*$*(+#%*!+#)"+#"#")+&'!+)+'%*#'''"&*&""+!""%++%%#!'''$'&(
@r5529
AGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCNCTGCTGGCTGATAATCATCACCTGCAGGTTGGC
+
(%,,AA6#7+BB.:&BE="355D@H>B!(<&H*D:ED?5',$B,"'?7/0;,&2*00BB!!C!(6A>;C;BB/6@#8+(-)*C#+B2":CH7('6HB&!5:*3$0B*,5::?(.)86B%04/?41FH"9#9-@F%12
@r5530
NAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATAT
+
#0%$))D23=16237)/7ED@;+8:0%7'<.$19?"E@0'3814;&F&-=:+--,6:9A:5=E
@r5531
ACCGGATCTGCACNACATTGATAACGCCCAATCNTTTTGCTCAGACTCTAACTNATNGATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGC
+
+E?G,:H2F:6HD#'E'A*8B<<&E%(05+(.3F0:DE#@;"A*5<ED35E4)+7C2F9(+74?*#<A;42/?*8'""#/F)#3&:<&(0!84<<@:4F63F<:6)>31$=38
@r5532
TTGTTACAATGTTTTATCTTACTNTCTTTGATGAGCATGGTGAAAANTGCGATATCGGAAATGTTAAA
+
$F<5%63EED+@%E:3=2?.5F!-!+6,.G5H9-/;D.F+$$$B8%G,*877==<C"CB*.+D#E0)3
@r5533
NTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTT
+
2-%70)>0;-.CHF?D%$48=C#F>%A-"H9(9&B:"<:B5*?","-%@17.<C%$1B2/C9/=<3D$
@r5534
GTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGGCGGCATCTGCGTCTTCTTCGGATGGTTATGCCACAGGGACATCGCCACCAGANACGCGCCGNTTCTGATGGCGTCTTCCACAGTAAACTNC
+
57BF(#'1?5$6B.8E&E(?<!5@$FD11$F5.'@H&D66*E<50GE'(0.7+,3:,%77A%4>5"68;)('*&)*9":=:7*!#'.8AC2!E1;$2G,%?'1%9(1HC7(0G57%!5$,>&>!H?#93+/E6,5GD41<*:$?.&*
@r5535
CANNNANAGNCAGNNCGCANNNNCNATTCNNCTNAGNANNNNNNTCGCNANNGAGNCACGCNNCTAGNGCCNNCANCNCGNTNA
+
#$#"!!""#!"$$##"$!#""$#$$"$$"#!$#$!"$$#!!!#"#!#$"$!!""!"$!$"#$$#$$#$$"$#""!$#$$!#"""
@r5536
NNGNCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTGTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTA
+
!"!!+$"(&)&&%"'(!#)'))##)$")$+(!&)"$!'#%)$!!(%*)%""+$"''*#!#&"'&*&&&+"(#!%((%*#")*'*)+*)'$(#+'%%')(!')#'"+''
@r5537
TGTTCTGCCTGTTCTGTACGGGGAAATGCNCGTGGGGTCACGCGTGGTTTCTCANGAGATCAGCACGGCAGACGAAGGGN
+
(;B&31#=:-.?0*/>,5-'!9B-E21,)(C.G&9@?-+;562,9BF:!&G;)CB+7=A%).?E2.G:.'4"04.E3E!*
@r5538
GTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATGGCAATTTTTGCGCCTGTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAG
+
020!"&4D1G0!/?3)=$C=3:<&)'&4@F!@D$+03FF;#=-,HHC7!9$1A=1H3$=DH"E"?#,,+.(*A+@0CC19:$<F6G->2EF)6$6""3D&>&F!D<!E>7/$%$'$#136*$854%$,:C&;B<6.#G?E.F5H=2@"93=&-)<6)1/B0G4?8::
@r5539
CTATTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTGTGTACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAA
+
/7$#.6,*:/'HD,/B-13!&H%:%G*0(#$CB;GH:6(5/">E,%#<:74>$FGB)(:*=A?A!#.//<9$5<8?*.%.H-3
@r5540
CCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGATCG
+
0=%)2-<:1'.;8D>1527,9=-<!1"%5+=<*A%F+4B;%:C"!8GA1B.A57:C!5%<,*'&;,.>:GD@'0938)&;>AB;*&0G8HBF06@@FHC.8CE&<.1!';
@r5541
TTGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTA
+
%-A)<6=*@<!=02?,FB!?<1D,>:#/E?,!G*/D07+6=;F.6.76<2
@r5542
AACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTNCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAA
+
"%+)$$!#&$%)#%%%'&*+%&#$*"+*#('*(#&"*$"#!(*((*#*&%!$)(+"!+)+(+#()#$$!+"(('''"))*%!#%&($$"*+!)()(!!%##%("((##&""$%!'"('!*&)('#!!
@r5543
ACCCGCACGGNGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATNGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCNGCACCNCGGTGGTGANAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCG
+
:E+!'A@%7:E';,'G"<4B33>6-*<C2+94*<*AC(GG'2-(7@=9%1AFH1.#:+03&'@<A75G#8.?*$*F;C314>:-G;*/8-GF'F2::4=$<%5458!+4:5%+7AED'="6'?,?;(5==%A+H40.+#:'-3(!A*:+E*&392,H1F!?0HA6$=)69>8%<B0#1+?8H--)3/9&
@r5544
NTTTGCCACGCCACGGTATTTCCCCGATACNTTGTGTGCAAATTGCATCTGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCC
+
">#DF1797+>;7/H6G5%E;/9/(.327'H*:()&74'8%6A?($H'D8$#8/,8C#!<#?@<,<>>3'+?',<C8,-/'?,8;:#;E/9/6026=("('8$<0=8-'%($@5@2/82'%*2
@r5545
CGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCA
+
>=FC&'+A!(7&@6:G77138$'B%:HG2B9&!.D+H$!94,<).H%@A.-F*8F".6@2
@r5546
TNNNGCNGACCGGTTTTGGTTCATCNGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTNCTGCACCATATTCATGAACAACTGANCAAACGAGATAGGTACACCGACAAATGGCAGCGACGCACACACTCCCNCTGGCNTCACCGGGC
+
)##'(*"%#!)&++#&&+#*!%)'*"'&!!%#+!)$)&(!#"*&"(&""+'')#*%*)(%&)"!()"#*'($(#'%*)(+((!)&%!%'*%"'('+$&!"#(+%!)%&$*")&'%%$"%)'')!"(&+(&!!''("*'&(%'%($%*&"+(($**&*
@r5547
CCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCA
+
3A?EEC-.E-+?6A<!%A0)"G!6*@G!G.)@563.:*$=/E:@>1#<4<C4B;54AH<9)+EG47#.D&:9F:/F.91E(/
@r5548
ACNCTGGGCNNANANCGGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTNGGTCCGTTACCGGAAAATNTTACCTGGTTATCGNCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATNC
+
)$#!)"&))(!#!"&'+++"('%*#+#*+)*%''#&!))!((!)%$(!!%%%)&"+'#*!+"((%&''%('+(!'*)*)()$+%+)$!"+#+)!")%&*$&)"!"&!!*''($%#+'##*"%*#"+#*'&#'''+!%+"&#&'+$
@r5549
ANCCCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATGGC
+
!!*#+''$"*)%%''%#"%*%)+(#&%%)&#&+)#!'%&+#!$!!+"&))"&!+!#(%+(
@r5550
GGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAG
+
@H3?G$('(E5?/898%)1=+.??=GG@!4>'./#,!$/:23;H9/2:44!G(6H4F$+E#&'00'35+B;23=";A@7E:*(5,.%-+7%4@@A!G3)6@
@r5551
AGGTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAATCAGTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCA
+
'9GF9@EA*)"A.4*4#(2-&;)(G"7FB7@2!%1'E@&41'!=A+$=E1%(6D(7@(7H/05F//B>E@9-+'*EG%!'1<>0G>'A!27<*6B+-0'E(FEH<.>#.)9GF+6,#1==;?/23)$13CG>4?/<E&/,)+98A=3<40G</B7DD;;92$DE'/9-!1;9(#7A420H+=$
@r5552
NGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTNATGNATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTA
+
CA)$=-83<?.H=/7$&77$+:B6-B:&";0!42;<,5A<7D$3C;B"B5B#-B)4!057!8DE":9>,@5<73H>F)?@()*DB9&1+0>E+FE.G%)?99%$)+,C)!.2;E3$=76!+4F&-7?8FF741,+G>05<.H0,4+23":B7G
@r5553
CCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACCTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCNATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCCGCTTCTGCC
+
E9$1$=;H?!5+)>G0H$*/<#5C5?6+;>*31$(<A?<,H7'C);E>%+14"G8;F&8)C#>FF+>1>6*0=!.HBCH'>"6'2/6=<*HA0&F%/G,'3?:BE!#32<&-+21,?4==E26"5FB,9F>B.1!(%H<;!)&,H!",E--$D4H%-1A3;+&?B!B89F13GCC945H
@r5554
CAAACCATGTCGCTGCCACTCGCGCAGCAAAATNAGGGGTAAGGAGATCAAGACTTACGGCTGACGAGTACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTNCAATGGAACTGGCTGTTGTTACCG
+
,%)1>#D"4.4%D08G6*B2"*(G#"6D$,5*+AE$.62<<&D%36(8;=?E'>?#$<@>C2"6.-5!C:@CE3G3*4&%).)8+.27F9.,GAB(2;)5="A4"6)(EH/@C87#+-)27=CG540/2AG)(H.A>G0.7@?H
@r5555
AGTACTACTCGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTA
+
?$5>=6<6,-"@@/%)5'G+="2/4/7*#@*2./H-/H8)5!1A74&@6D'4A%A8B>>H64-/
@r5556
GCTCGGTGGTTCTNGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCC
+
BFB$=3%D4GF?)352#?7&*BE'<>@#>;(:A(?(19/3,'56C2CF(&4807C%!G>(?DDA)83).+!!>=<G@;B&>)#%!5
@r5557
ACGCACGCCAGCGACGTCCAAGAAGCCTTGAAACAGTTCGTCGATGGGTTCGGGAATGCAGGATATTCCCACCTCCGGTTAAGGATGGAAGAGAGTATCTGNTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAANGGGAAGAAGGCGAAGTCATGAGCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAANGGATATTACTGCTACAGGGACCCAAGGACGGGNAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAAGCTATACAG
+
F;B0$=B7930=5@58;@+9D2BBD1@6$E;/C0E6)*$1;'><!/4A;4)$69&&7)*#D1%HC%%=3;5!--/385H49#H<=15#"6*'006.2A=&(>!0=:933/*!=1)2F5#%%1'CCCG:EC$"-6!48D4>#B;5#/#B8?3C)7;'<42*,*<4>D)8:'0*!9B'19#1GF*/,+6B20E)&(946?&HA+69G="5F481E83AH%8!,F#-%316FA/2;&H1*AC@'5#3G<G0$5H6/,2,?$/7DE9@?4HF/%39#:;>A!G)&.?&*+10?3./1C0,%8'=0%"2-1"E.+.@9%A11;<63
@r5558
TCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGANCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAAT
+
'$+"%((*+!%+%%"%$*'$+%(+)("%!#+$!$&*)#&'(($&*$*#'(#%$!$"+%$"%'%##!(''$#!)(%+")$!#$$)"#$!&!%&&')!#")(#%'(##)%$*$$%&)#&(++!&)')"*!!(**'+"*!#)$!"!#%!(#"*++*'$!#"""!$*+)+!(%*&$*%")*$!$#+)"!%!#'#*$+%
@r5559
ACCAATGTGGGACGTCCGTCGATGGCGGAAGATCCCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGG
+
/7C;%'7/@G-?!,)3#@1F1@;F"A'&.,7,+9(H1857%<30<8,"*9561@2+#7:'B4:48,*/"#)6(;-79:5("@A,6:*?
@r5560
CTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCCGCCGCGAACG
+
HE".3$D@7.E%)G3$<(<3E@8>"8<7;!5DF'=$3H6590*-*03*EH1AA3"5HG96B*%.F*F(2&<#"6/
@r5561
NAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTA
+
$=?'?@1C"&40@&E8:1!B$@>-%=B,++;D>D.,.$E>;/ECF*-;B5A6%E*7BC&::/#)C'9'3=&&7192:C%("2)!-1.?+,%@F></BD'4H
@r5562
NTNAANANNTTNAACTTCAAGANTCACNTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGNAAACAAGGTGATTNACCAAAATCGAAGTTACGAACCAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTC
+
"(&#'!*!!()!"'*)%)#$%'$'%"#%)#+)'*#*$"+##*$%&$$'*""+#))!*)&#)(($%!&#')!+$)!&(!+$!*+#$)(*%)!*!+"&"+"&%!'!!%+*"#&(+*#'+*)("*'#!#)'#'&"#++"+$#$%
@r5563
NNTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTG
+
!%++%$"''#%(*+$&%+$%(%()"()+&%#")+***(+!%*'$%&)"*!""+'##(*"&$(&'$*'&%
@r5564
NCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGG
+
!@FA/205/6,&+(A$A,/$5(0-<F!6E%8F-#*0@@E#6;,2*016
@r5565
TCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCG
+
G>C6D#>!/8718"%9-<)>/+-<F%":5:9>/#+(+B*"3!&3,+945(FD,
@r5566
AAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGC
+
8<GD834#!4+-2@1%.(DD=%9B.8.E31BB*#&$=3F*?$!3%
@r5567
GNNNGCCTTTTGTTTGGCGTTCTGGCTGAGNTCGTGGTTACCGCAGAATGCAGCCATANCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACC
+
*"!+!))'#('+(+"##%+)('$#("&(%&()%(*(%%(+#)()%#)'+!!+&($!&!"$+!##+%(""!%*!%*+&))'''!"'&+&#$$'"+*%'''*)$&"##)+&&(
@r5568
AACCNGTCGCACTCCAGAGAAGCACAATGCCTCNCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCA
+
$04>.C.E#-0E11%!@<GH!6,=<$0&A'=5#CB#&+)05B*4A;A(/*&=0*+2830CE7-EF=2"*1<FEAF$;+H%)0!FH1#D&277BA+F,%9)0>"1=C4<-&1-!4!9;-7G47FG0.B@D'?==4)E>D-F;6?+/,(AC@A$7$
@r5569
CTGAATCANGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAG
+
G/*12>#,;=4*7)&:):9&#41F7H3*9'"C&97-87/5.&:<<=
@r5570
TTTACAAATCAGTANGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCANAGTCGGTGGTCCGGCAGTACAATGGAT
+
0$>'EC,E+;=+-;=$@*(?:@<$D(G</&E+2.C311698)"C<6)<,96B:&6+*A(95F1-;2-,>"&C?7#GC9"
@r5571
TGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAANGACAACCCGCGCATTACCCA
+
),A?*DB%3$1)64!B$.#FC#*<E1A,.$@-FB488.0CG8/+.B0:F/FH%6F$%$&
@r5572
ATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAACCAGGCTCGCCGACTCTTCACGATTATCGACTCCATGCTCTTACCTGTTGTGCGGATATAAAAAATCCCG
+
-@=(<494%5%&!=:)+"6&3H@G/4>@#%915B<,+)&5A=1)&2327*>F5%H'?A$6?,61?0;;7-AC57:?)54A3.4?.H7/001H#5$$7$)A7)H*.2,58=D%(/2-5&#E0.!'''/";,?>*(//
@r5573
CTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATG
+
*,A60=6*@D*-+666A/(#C@>13BA)<B%#C,/7:;H!F)!(
@r5574
NATTGTTGTGAGTGTGGCGATCCGATAGATGNACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGANGATCTGGAACTTATCAGTAAACAGAGAGGTTCGNAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTG
+
':A%-:>!6=82(<(@310$/?##3&G4#.8B:-37>8.:)#<743%8F10A!*../2(>A&0"(40'%G+/9)H+7-CH78-(4%);(,$1(A4G@47F@:C%=/G:AD'*28H>#D<;*@5@H09=<?'H.6C)129A>&?6+6F2+CEA(,4?<&D8&=/'".+1<%<&&9#-&B,*F;E"'':".
@r5575
ANNGTTTNACAACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACC
+
)""&**)!'#+&*(!)")##)'$)%('!&%%*)%'*%"+$""!((#"$*"!*"#$")%#"!"*'"%&+'&$%%'%"'*#''')"&+$+%$*+!$#)+'*"!*
@r5576
CGCCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCCTGCGTCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACNTGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCTACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTNCGTT
+
-9*4/&*7%=%>&-)E*F)%52=.)':C6?91A:E.=C@830:?46!E9@(;C$*95B"/<-9(6;#"@,)G;2?35;+,'<<>$.57C+@+)$H0-0(4BB@?3-8G@1>&B+3;<./*856G?C!*8-H@/H/4!EF'4*.116F.(#D&(8:'!9)=,+.:97?$D@=!@%4"::%5&9!='-.0%-F(02#E$E@1',&.>(D:7;/7(4G@48-%?%;7$,G/87$&-<878E7@9=F2&<=.>A@4H):6F3A4&7-.>0++'2(@BC0,'?$198E.0**4+7509?2(+G.'G/=-C4A(9@&3)<!$)&?.?41'(.*12,*07>('D3%:0-&29(>:B9>"*':C02BG:=(%),G&;=>DA';:2B+1&*A)872+$%7/E$D%!$)!.8</F'1-
@r5577
TCGAGNTTGGNGTGAAGCNGGGGGNTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCANGTACGGATTGCCGGGNGNGACGTNAGCACGTNCGGGTTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCANATTGTTCCCANAGTCGCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGNGGCTGCCGCCATTGCCGGATC
+
#"&'$"&)#)")((#$&%&)'(&&*+*'!+#""$$'"*''!!%(%#'%%$!!!"!&''**((!%#())'#*+*$$%+$%+)'))%!$%%&"%"#'((+!&)!#%&(#%!((!&*)''(!+$#)&$"*"*)&!%"(#)%*$+()++*%")+*'%#!*&)'*(&#)'%(!!*!+#$"+)!#'#)#%+*!)*)"#"#%('+)'#""'&""'+*#*!!$%'*!#&+(+'!!!&&#*++$$*(!'"$**%'&!#"+"%$#(
@r5578
AACGTCCGATATCACGAAGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATANCGTCGGCAACTTTGGCGGCTTCCTTTCCATTAACAAACTTTCGCNGTAAATCCCATGACACAGACAGAATCAGCGATTNTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAG
+
@;H*CAA=)$8D<7E@?6GD(#C$-.:"@7HA0)"8*94(E$>98.00;A<!,#++74&6<1H!8-.G0E>@CB;68E&(($2&!%%E?EB0;;GH4#70<$&2>39C(GF/1'#3,8.@@D0G*E$E.*H'E,/D&$-"5CH44)A-<G:"(.-E:7)))@7B%&!-'#B?7&"$
@r5579
AGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTNACCCTG
+
9)!AE0+9+E2H=?"@>E&19G'%)&"(&)$28!%H8#.+F*B<C##H
@r5580
ATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGC
+
2/0*5F("E%;**?<?',>0&+*,E9@6(@$1>+:9CBAEE10(7'21,9;DC
@r5581
TATCCTCCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTA
+
,'G,E&H-!*:89'A90.(F@0=1<!=F/#&93H0D6F1<->!9&(2<'+<3D)=59!G-=.C@B.75%.B-%+>$E;)AE4
@r5582
NGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCG
+
!&'B4G38A'?('05!B,H2"*3(*C<66:9@-98&2"81@%1?.@8&6EBE=!)5<!$+///?>%+;DG.*B%C)(!E:+&H-?@E#./!13:*(4/4/F>.
@r5583
CGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATC
+
BDA6D#3&%;G4!!;,D)%@<$>+E"2/'364$(6C*8%5';><=37.#+;*@?')?'B30@<9>(&G.'3BF(11=).-=@$;F)&D>8$
@r5584
TGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGAGTTTGTGGTGAATAATGCCCCTGAACAGACAGAG
+
9*;%>&,?B7'D8C#8+B=5)73'=E(A$*6H9;%5$887+<44C@",,8B)?C)&FF&8@#":5-:6/)
@r5585
AGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGGATGNTGTTCCTAACCTTGCNGGGAATGGCTNTGTGGTAATAGGCCAGTCAACCAGGAGGATGCGTGTAGGCGAATTTGCGNAGCTATTAGAGCTTATACAGGCAT
+
+,HC:E"H23"H>B:C>86BE&8?!@.0,6*-"(4CE=G0$<2@+A2C,;?99F2?70+<H*B>:FED@467#C3*2)C7B.1@-F:;8#439H$B>*3,8%6C9(3)D"/G0!A%=(F'?,(((F18+:+,');B-..1A'=69,/')
@r5586
GGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTC
+
#G1?:,:G%5!*A'A06346036E5&H-.'3&&,<H9F777(.8B#&5,+:G/@4*$(H"
@r5587
AAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAG
+
D$?&C;$)$=6%:(B90<.&>E>><)2?.'"6;0$D'#*.
@r5588
CTCCTGACCGCTGTACACTGCAGCCTCGNTATCCAGCACNACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGAGCCCAGACGC
+
>3BBH&!%!@!+4"3,2490A,)1)"(%#=D8/3E=)A%D2+@2F2C":2H3%87?.!<5C8>972/%8/@1?!#H@,567=00/(14D,F@?A.DG;G+>.9>)<A,!+F6')G@1(#.*<,2(77=H'!*EH1>8(H&-1-G,BH,C;9(G?H@-=11H)#H,>+:)/!)>?D*,=FH'0$6):6D;!$H?,*,AH=>4(@6G/:*.@>!(B98>7:3;&826=;AB;&EB@)#<.3%26&'/24,=7+35@(H-1<C2(5+*?,)6*3*G**>F+,B+9(7C7,'9
@r5589
AGTCATCACGATACTGTGATGCCATGGTGTCCGACNTATGCCCGAGAAGAT
+
(D234G#!H%0G1+H9/-*@;$6!?370B(A-&2)GA$.460*5,5/'!?C
@r5590
GCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCGGTTCCCGTGGCGGCTCCACCT
+
,3B=/0:<&G>-$"H@91/%8-,.+7-'H-#"G,0,5CF#!@54-DG#>(-707#.+<'
@r5591
AACAACCGGATGCTGGTGCGCACNAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGC
+
$2.9!AD,5A,@A898:<5;+'&D=(/7(1,!H522E35##!9FAD-!>@9AD*%E/&)5!5F,3'.D&':C!/9@E!@),""DF1E;2"0/
@r5592
AAANCAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTNT
+
:E1*,$9(0E2#G#5"<4#1=3+#7&.2GCE>F0?:?E@D;++>:5$*@
@r5593
AATANTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCANCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGT
+
?CDA9>4#381@FA?#-;#;8C:D)0%A0,A+6F*>2G,#80"=HBG.(!5A$"-'3&&:H@@&<E,'?F14?&E*@#C@B$;E>?.(!09HE(,1E4+():&$-8G,9<3;!$)C:=DE)!E%&F5#AEH@G%=!/88F*/-F%46A1,EH:%?6C(&D8-CH5E77+F'BF8*+GAAF#%E<&-332:H2*5E+FB.#:D+*C-21G@5$:?B!GD=CB@+C60/::=)>1,G9.<86?$;%1E2+E@B6,=!C?
@r5594
GCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCG
+
.7=;!"D>>-4$?";2834"BHH?::E<+//76&1,,5!)+"95/"D05E<4<$-'
@r5595
TTTCAGCATTTATTGGTTGTATGAGAGTAGATAGAAAAAGACAACTCTNGCTTGAAGCTATCAAAAAACTAAGTAGTGNTGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCA
+
E:D7:-85G;#.8?:1"9E-D5>E8&)@.#'9:$#44@6?,FDD.7302D!;$9#=*''9+-FAD&5@:FBF621(:1!1G)+**A$>'FF'6?9+)C5F$""2F/E0+*%-98$.&3)#1DAB0*$4:1AG:G.G>6E@F+E;A;:;1&(-61>#G:$8:B?EG)EC%0=168%74
@r5596
CTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCANCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCAN
+
+GC!)<(0A&)!$G-+D$ED6FH>3-E".73'=;,&-).<F75@E:4<D'?>B+**77>:0:F"+/!!H3<&$':>5(#0H/$)6H6=>$$A';.7+6E+)"-HB>+B5;7'H9:E-!G?:@('#:*&+8
@r5597
TTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATT
+
0@$5@G>;$,5:D0)/?F&1?*''*!$23D*"B*+$B+%E(($!G!-4@F#1A650
@r5598
ATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTT
+
;#()8$'?$2GH.C?022++<5#/5H3C."/$F-1=C;9D<?':8E3&B#@$"B'-"H'2$",-E=3&8A:C
@r5599
AAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGA
+
%-%#A#&3,-,944!$66%322&"*)><E*0EGH,6;DH=&7?"@7$'>F)(2B%B!$/8)EEB12(-62H=56#C0AGG
@r5600
ATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGATGCGAAAAAAACA
+
6@B/!C-%:%,%7GC@H0$1..,BG<B<7/%G059<F(<1/3=<'%C!(79$!)#@?24/()<)B9<*/76:#DF13
@r5601
TTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTCAAATATTAGGAATGTTTTCACNTAATAGTATTGGTTGC
+
'0:E3908-97?*,&$)96-@4B@6F,,B5=70$?4"B:!G0F9GG5H2A3E(F<$2G4C2""'F%!F+5!&4A$-80*"BH8)9?AD=(2H,$8$!'-".,F8
@r5602
AACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGA
+
C+B@>7,.&+9H5H!-A'6."17@53=+/*93=/G;'"DF?8>:,"G7/+C59;*@?
@r5603
ATTGCCAGCATGGCCTTTAATGAGNCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGNCCAGCNTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCACTCGCGACGCTGGCATTATCCGGTGATGATGACGGNCCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGG
+
0*2)(4D%>@<H;:2?88A4!C960<8;DC/"(G'.::%8&6:@/>%7//?A('$.G+$:D":AE<)A>ADCG'?<)8)-++!<1'01B7457+.A>)5F09C2<DD21215?2EH:>>EB(1H?EH+57;'-$:*:&&7%-#$H-!?F(3=?<1@7<C.EB#6H1H:'=(:8/?!G)*:98!&DB-*+@48=#'9,,C<4D"E.7DH=E12<D&3774ABA1:$&6=82>14H5/D&<?(A'CB/86C+H(&,76(?20"@A4H;507,*-)!G+@$G#'46*.$H
@r5604
ACCCNACATGNATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCG
+
)%$$!!*("$!$+**#**$"''$'%"!'$*#%'&*)!$""(*%!'(()*$!$&"**"(%%%"*+()$%*#*+!!(#!#$!&%%&"#"%"(("'&"$"&(#&($)*&*'&
@r5605
CGATACATCAGGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCA
+
C)//)>1$80>7>E2B(!337+(!/'%'1/G$.H81*:!H;FH/$4E=3*3"@-"(>E(307$H4:C&C%#33A$%A9G2$!'BD43&,"A?9D$6520E-%DG02.>9"+4.4$>@3H,$:7C&
@r5606
CTNTNCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTAAGCATCCATCTGGA
+
'%'#%*++''#$(&#)$*+%$)!"'*('+()("(&'&+$#(+&%$!!"#&"##"+$)*#""&'
@r5607
TNCNCAGGGACAGTTGCGTGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGNTGTTACGNTNAGACGGAGCAGGAAACNCACGCCCTTCANCACCTGCGGTGTGTCCCATCGCGCCAGCACCTGANATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGAAACCATTCACCGTGCCACTCTGNTCGCCGT
+
&%&'%'("))+%%)+)&*'!*((*)'%&!"#++)$)"$)'*&++)$+'&)'$!+!$#%*''%%+%'""$&$+'*(**$"&'$(&&#&)!$$((+)$%%'*&+(#*('''(&$'$+"+%#"')&%#"+#))#$#!!++""''(+&)"***%**$(%*&'!!$#"$%&*+$)(++%#(+"(%&+*"+%'%)*'"!)*%$++$"*'&!!'%!$(&#('%+!")%"*($#&)*'!"'!)&&!(+'(%
@r5608
ATATTCCGCCTCATACCGGTCTGCCTGCAAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGT
+
9!/"$BH";HH6B9/7C*@'@1A0=G=1@<1?5;4F*!"5;52;@-@#$=C;HC;C$&;ACA(0DH-=BE1C@"&%#)6C%:HC?'(@=)9+7>&F%EF#$8A>03*'D.%43';,CF)(6!,9D/#B
@r5609
ATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAG
+
*<4-?)!''?$5)7:7+-!7G>.)'=#,4(#%=892)#A=G:8?-$-
@r5610
CCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTT
+
)-9H:E!>@,0,$H3?E1979;<>1F(8="!#7#37$:$0#;.)C
@r5611
TTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACAT
+
8,B;#$926A"8H>4*A=/12@%;2:H;8="D,!!1780$/,7A0D!E$@#3
@r5612
TCGCCTGCCGGATGAAGATCCGCAGAATCTGGCGGACCCGGCTTAC
+
4C;G+:6+&7F<%D)8E,&0?<26+#0!,740(9G/D2&/CH>56C
@r5613
NTNTTTTANNCATAATNANCTGCTGGCTGATAATCATCACCTGCAGGTTGNCTCCAATTATTTGTATATTC
+
%')%#'%'""()(%%(#!!+)%*$"$+###(*%"$#&$(&)"#!%"&#('"#'$"$!()*##&"(('($"'
@r5614
AGCAGCTACAGTCAGAATTTATTGANGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAANAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGG
+
:)&@'?C0@"+!<</'0'1>,<A2"2(38$0.8"+!2*4:!%"9$-,2;GED+91"8E7C8,A%0(36D2HA"E9:,/#H;8*G%4'+?*/8<$%#,@B+5F0'<0A4"G@2&128(/>)6115
@r5615
AAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGNCTGCCAGCACCTCGGTGNTGAAAGNGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGG
+
D((*&E7#<.F":3C6.BA6?&9##B+*1A(<!!%40%GB'4)<(E,6G-(9@@5;F9,':>)E4H$:E*DG7*05=$C6:'#--A-84:(/HA0')..8+/8+!"=;2"C%0H26/10;7)3DEE-;>(A)G&<03/G?.F816D/&=G@4+,5F>-(
@r5616
TGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGNCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCANGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTC
+
@;:<=&6262A2(?5C%<H>+E6#B#B?,B6'>*A'D&%"#0;..4D#$#A$)@=6D'DD98;GC@0B7=>4@$&CFA2H=@D$0'>!(&",7$9C5&C!-&).5C<#B($;!/%8)-=$=GA3!8FC;GFH%;$#87C0)-3<G=A7;>5GF"2+?/B6,#96"2/0.0+<B.'A@G:B>7!6*24A3E2:%E2<)5:&(7<*@1/0+50*)&F2$0-)#?+;"#B-$(8:->(C=5#37
@r5617
TTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCTTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTCCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTNGGTNTCGCTTTGCTGCTGCGCATT
+
#:&(7AB87(0%&5*558H&7D1G.*51'2='7*+C6=:,F(41-"<37+D:731;'&7;9&,00"5990/&)5+@>?1*$,5@9!BB36'/B;H;)G<2-&H="%GFG:<*/F15,*>)<!+:('&E;,E>>2?6E6,,%!.3/*(21-+G'#07D(!6/D4;>(1&F?4%.9(C740:=9H;>26?9C>B38H$33D<794/7#14'A?4
@r5618
AAAACGAGGGATAAAACATCCCTCAAATTGGGGGANTGCTATCCCTCAAAACANGGGGACACAAAAGACACTATTACAAAANAAAAAAGAAAAGATT
+
@5=C&3:*830@),A:C$$F0+'5GB15!D&5$B1<25A14*,968,G:.@6#?&!57)"6'6#B8%@"D%*-0=,A#,G/91)FF'?9@G);EA5)
@r5619
CGGAAAACAAGGCTGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAA
+
&.@F@#,AH>%D&3D+5&E@0;-+=-52!6=%)'.-6;$)$(>;C).(+'*2#E.G@#+(A9!C94$$;$(&#C)G&6#*=*42%*$AD9'9A9/6?4
@r5620
TNACNGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGNCTCTCAAAGTGAAACGTATCCTCC
+
&"&'$'%''+##$+*$$+!+()!&"')%$+)*+"*+%*&'!"%)$()")!!%+!*)$!$%%'&'$!*'+&&&"$#)++
@r5621
CANCGTAGGAGNGAAGTGCGTCAACNGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTANCAGCATCG
+
)%'$%#'('*("'#%$$(+!!&)#("&#$+#'''$!!"")"&('"!##()#%%$&)("#$(%('$''$'$"&+%
@r5622
GATACTGTGCCGGATGAAATCGGTTCGAGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTG
+
;+G0C->"D.H.<"-+(A)%5F.9=/@)'0/5$BD@&B;>*D">&A@4+0H">AD9%E@"=C>B,1&(17159>%268$'A?$%$BG>B,)!$-D,.
@r5623
CNANNCNNTGNGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAG
+
'!)##*"#&(!#+"()*"+)%))!))"($'"$*%"&'#*'*)*"&$""#))'$)#$$))"*"#$$+("$+#"))(%")'+%&"'!(&+)*#&&!&
@r5624
GGTAATAGTTAGAGCCTGCATAACGGTTTCGGNATTTTTTATATCTG
+
H#"H':."-&8;350E2>ED7<'*A6&2%3<6C!(:64!#,,8H(@F
@r5625
NGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGG
+
'("*&'"+&+%*##+#*+*#+'")#($"!"!(!#%#!&#)
@r5626
GGGGCCGCGGGNGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTATCCACAGTTAAAGGGACCAGCACACAGGGTATTGCTTATTTATCG
+
7+A82??!;HD&+()!<"3B<3!-7H'4=HH/EH#@C++3E8';9<?B)G=#)93<63;F-!.$DD#2G7=$/@G7&D&("H<!2/#A;C%.+$7=(?0-=!E29C)?*0:A*(CEG$=+,B7.DB;;*(*HDH+A=,
@r5627
ACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACC
+
5-3#161>8G@=927>-E.D!,6;+@!0>>D,5-(-:=%A5.C<4:88*"+.A!12<%8'7G)220H9;G",H7@
@r5628
AGGTAAAATTTTCCGGTAACGGACNGAGTTCAGAAATAAAT
+
G#,.*>4.',F'()#89)#>+?.@/22/0<.CBC/?&3&-%
@r5629
ACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACG
+
96".7=HH;0-G.4#@8H#7B9C17:C55D90)F@#51;>D94:;:+58E$G@:+9/.1.6C$7).'6:+1A:!HG27(@@8,30-8)0E0;)<>
@r5630
ATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGA
+
%EE7@7H@>AF:<!--0*21->/?BE#<3F"'+$?%?E?%BC9016H-//B(4F??"E8',?'2:"
@r5631
NCTCGCGACCCATCGTCTTTCTGATNTAATAATAGATGATTCAG
+
%!++&*#&(#'#&&*&%")#&"&+$%!%+&!*!+"&&#&)*"!)
@r5632
CGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACNCCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGNTGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCCAANTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGT
+
;AE1>@7=;'7-)"#&".B:#HD#=-*!,@E,>0G?-,/((7282:&C9D7)(<#B*!-FB:)A4D$&-</'.G-9/A!0+=5).->ED748>B>;8<2385-G8FH+)-/(2,H8:6"@%;&(16(35,>%78:/"+8+AAGH):@'$9&EC=7"+8(7>6!ADG'/#-3"<(0/1!G!1;44#;8"$C?.;:(D7#EDC!0%32B%>*:D94575A:D!<="-$7?*BA;=F7AC-A2A7#:G4#55D=@+&DG=.+<B!.'-%D<H@);-@=B7(<G&#HH0-G.DH/!,5%D>CDD!H$HD.
@r5633
CCCCCGTCGGTGACNGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCCTGAT
+
$(!+)&%+$(!$**$%'"'+&!("*'#&)$'#"(")%)$(+&&&)()!"%!#'%)('"+%(!*'#*"#!*'%&'%(#')'$"$*)'!&&+)"(''
@r5634
ATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAANGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTCCTACTGCAGGAATATA
+
+%+(>-/E!+0/%7:%48**(@.,76*%C/31=:""$4A/807D="%94@3A-/6G-.29F2C.C2?,4-,?9,284!@;,8A$?E8<A,$%%:&6,E0$+8<8)7)-B)2=2H',;/3<)D"A(!
@r5635
AAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGNATGNCTCAATATCCGGACGGATAA
+
/7,5GEH)"!'G84$81<H639$%8)B11$:B/0GC3("H0#(G2+#?%C9=+#*4&),@8.&<$95<
@r5636
NTGATATATTTTAGAGGTGATAAAATTAACCGCTTAACTG
+
"66,&/4(#)F=7*$E><+@C,GG!2#+!8&=%*=>1@A@
@r5637
GGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCA
+
!'+)')&"*!!*+)*$*'&"%"('!)'*")+&$*'$&'($!$#&#'%%+'")%&*!('(%&"%(&!$%!&%*%+
@r5638
CGTGCGCGCATAAANTACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAANTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGAGGGCAA
+
E)0$84D&C@=*&/+C=72>@<+F"FF14'+A?%A'HEF*C$F2E''.H/$68#:5*@+,A1;;4(C9'6E%*-7%!F27<1+91D#3#"5%G"ED5"!(:66,'&5#>$.%:??1-1H@/:*C+,8G,H:BB)E>!!/;'9-0,B8F97-3!::(*(G=
@r5639
ACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATAACGATCATATACATGGTTC
+
'+&/"-B?!3&"'(>,''@:8*E$3AE&2>7>H=G22B4*=!,.;EH77E-?D4B.7"*%+&0!12-3:'($5FA<08@0-G#;*"844<B"4G&=#
@r5640
GNATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCT
+
',?9H(?6E/6>13"F45EG;B"?"/'GF9><C?.3&?!(53);>H!57A-#F,-7@8:1#7@"4,=6G295%9">2;8-:+'-%@<4)&!8,*9-'=10-&F"G*G=C4/=-&037
@r5641
GCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGNAGGGATTGC
+
'>#45&/=?>&>!A).99%#G*F845#7>)6D&$(=74$:/2(:3#&/GA;A(*?1>
@r5642
NGTTATCTGNCACGCCGATTATCCCTTTGACGAATACGAGTTTGG
+
%:GC:487@)G7EH"9G/)8-:(10=/,6!":!8'1/D=12=?F&
@r5643
CATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTGATGAAGGTGACGCATATATTCCGCCNCATACCGGTCTGCCTGCAAACAGTNCCGATATNGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACNGTCTATGACGTGGCTNCCGG
+
DD:A40)4=()1+&AHG4+#,CH0-,#(&7/;0/'B>-C*F#2F9DH=@!%6B7B:/FB718E**A<%<$,8>@&*DF&&:2F#3"'%F7CB5C-E*,-=*3G'D3*B/-011,'$,%G71D&#*D10#EG1<F1"=8H/(8A,:'=(,FF94*91*;$8>6H%:"%(#16<G5$1#C/&+*(B;)#F>=-.!),E,!(%&(/#=2">F<%*<
@r5644
CGCTCTACGNACNCGTTGCTCATAGGAGATATGGTAGAGCCGCAGA
+
"&(&#'!''"$#%)(+#%'$&($(''"!'&&#*'*#*#*(")!+"(
@r5645
GTCTTTCAGTGCCTTNTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGNGGCGTCTGCAGNCGTTCATAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGATGTTCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGG
+
?HF(03=(7H1$*=4,FF=A+7,B@/5C)ED("':?HA%8DHE)6E:<E&2B,$.99+6/,*C6A7.:6;@,&F#3(,FD/!:3+/-2D(<'H/H..AD9BH!;--E7+3/+A4H/@3%067A1#H-)>+/9"%AA:<'</;.HG5+59E75DD/24;.5*"C)3E2@F=&G4-'
@r5646
ACTATTTAGTCTGTGACAGAGCCAACACGCNGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATNTACAATATCGTNCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGACCCAGGCTGAGAAATTCCCGGACCCTTTTTGCTCAAGAGCGATGT
+
E)1D6%,@E@5>$H@@H47:)G!&>$1;5@H&48'G=.2*0>28@D3F:5A+$0+8.!2)B/=1&02,@+8(:5"(,@55=/5=H$CFH:C;#B("-,2,?BA,=03G';A%.(:2-(3B,$?7$)3=26/+'=(7("G!H;93@575HGF"A*04###><!H/0B75<%!??.!0''=B<+2#8:G!3','7,69@C$!$D"(>)B0D=D>:70%4@2C!DH5<26<3B9?/D.1+5C3$2@13$49,1456>)"3=(
@r5647
TGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTNCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGAC
+
;@=/020(2,CB;4<2:4F%;C),BH3B@977*5?#<:E1,1E+2#C>EA@G,%"$.21<)8'@(HC01:%,59AB%+/.@
@r5648
CGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTT
+
%*(*%++')"('+*()!$+$'*!++#''!*&$!(#"&'"(#++"!%!&')+$*!)++%!'(((#(!#(+"#+'#&%&%$%&)!"(
@r5649
CAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTACCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTANTCAGTA
+
E#59-'*9,DF*+<".C<08%29?@+FC%<C&#$=>5C<D.'"1.<&;D:#9H,61G!!@<4G>H&=,:C)6@8'B49"!@9?HH"C7*>59;/*$))!(6B084E@.D7C-/5G"-+(1G/(7#9>D5
@r5650
GCTTTTCTAATTTAACCTTCGTCAGGNTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTG
+
5=,523(B9A='<#D+?&&)CC/;381$$7AE*;:=8)4?6B$:6/.#&+G2*F23BBAF0F.E=;)65'+&19=&&F((9%8DA->=,:1,.8<GC),/552A-9,4*,-D
@r5651
ACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTNGGTC
+
F8<"D.G7FH';<+:/!(G=@3*@>',H*)>4+@C@:C>9DE%+?.)70F24GH336'4*)+F@A1F6!")3A>+
@r5652
TATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGT
+
+#++&&('%"((#'!$'#$+!!'(")#**(*)+(($"$!("##!%%"&''
@r5653
NNGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACT
+
&$'*+*$$$"%$'%+!&"""'*%!)%+*)&!#%)'#(++('&#*"()%!''!*(%"(+*!%*%%$)#****#''!&#%'+)"'+&*""&+&%#)'"'%(&!!')"++"+&!(()+$#$+('$&!)%%(!"&!'$+'"*)&#!!"%#*""')+"&*
@r5654
TCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGA
+
!B9G!D0G<3?'31F0?E.=G:5/9%A-$A')@6"!H@.'D,G6C4@/AC.0"(+5A5@$6<F&?D?<A@#=H"16=.:
@r5655
GTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGNAGGACAA
+
A$3@$"E80+&A!%F2(.#+6)(;"7B@/9"??#->7B),%71(#>GCA??>:$53!CC)@'7%!ADA065?!F=6(3-=9($:#F1DA=.E+:.=E':"46,/$A$-5?0*+H8%AHD$D-.;F1H6
@r5656
CGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGG
+
(60@#9:70F<!7)%F(/,.>5.>(>A.8,/?.=03+,!$
@r5657
GCGACGGATTTCGTTCACTTCGTTCTGGTCACGGTTAGCCAGGCTCGCCGGGA
+
48%@D((>?+*(D(9>53HA-5F#@34&B=D+B)495<8<<#;2.>=!9G6A;
@r5658
GCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGGTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGACCTGCTGGAAACGCAGACCGTGGATTTCAGC
+
D=?C4($3:"$6:%E++.=@;.);;'8$>H*B)##*"3"=<+0''EDD?.<'9%3F8"G2=*3E;:F.6F2?.--E/"+/)F8-8BH-:30)B)C<2/7H*D:?"*09&,5ABH&/).8:C>8D0BCA=.%71<=B<3CB25FH+D6&8$FA,:"'*""D.A$99(,265E!;89E3<G9H5/42A#*44G21=H9.G36-)-<A"$7;H'!(>BCFC.0E$5++?&.4
@r5659
TTNAGTTNTTGTGGGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCC
+
&("*"&*$!&(#$'*%#+)$+$$()%%$+&&)!&+%"(%'$"(*##(%&)!%+*'+)++!)+)%$&($#!)((!!&+))#))!(#!"##%+($&#)+'#+!*(%&%*!&+%'&)!!#$!)!'++"(*##"+'*)#'$%%(
@r5660
GGACAAGGTCGCTGAAGCCTTCGGGAAACTGACGACAGACCCGACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATAACGTGTCGGCGGAGCAGATTGCGTATG
+
A;,:<"E>6&,.56'E=E3(+55/?,C+D=.!A<E2?@.=BB@1,H5+0!+$@)<3>F:<C-!$FF8A"09F$8G@8+:>@8=A<8%;=)#4*5;"@=!+'<9/.<!
@r5661
AAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAACCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCAT
+
26DG@8%2G@E$1'8=#07(<"938(DA&"B4C&*-#D.3'28;98?F;@G;?-@B>;#0<H7)>"!)$%=*4"%-1*9+8)6#AG#2;G/37:)8.=*'
@r5662
TANGATNANTNGCGATCAGTAATACAAAACCTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTAC
+
!$$'#)%&#"+"%'++!&(+'"##$!''(***"&*"')'&&%+$&+!*+%!&+)+#$(*'$+"+!#'%!$+'+&*(!*)$!*#"'#"(+&'!)&$
@r5663
AAAGTCCGNCATCTCAATCCCCGCGAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCACACCGTGCTCAAAGCGCCGCCGGGTGAGATGCNGCACACAGCGGAACTTATGAATCGTCCCCCNGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCGGACCACC
+
0:14$&;F2@GD$F$1+1@#<FF9@($BG7A#88*.B$D',0B$F(:F$C>GB/G!<:F"0),,"CD;0B20A:%+D3#7,>6>>7+"2(6@"%7EEBH4A)D%CD2'FA9CCB3-(=%H.)3,C;-5:5.G..";G$-;+"G&1G.G6%;B+=3G)FB498'>94CDB*!#8$4)>D!$)5;.8436C'?9D-7!%E&09E.<
@r5664
ACAGAAGAGCAANCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATT
+
'+>F&5:%?E4%<7H,*44;37-<%628=>DE!1)<1;:=48B/$)@;7?'B=:<+>$;6@'CH?<31"&A$#>
@r5665
ACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGCACACGGGCGNTNATGTCAGC
+
E+&@'?%*'(=7/6B+=,H*)/%E8?>8A:"1;AB%D0>,*D?HG37F5>&ECB(*<>.!F)H)#&H6;<:2H#)
@r5666
GNGTCTTANTNNTGATNNTNAGAAANNCATGATGCNNCTNTTGNNTTGGTTNANGATNGNANNNNTCANCTTTNCAAANTGCNCTACACGCTCGTCGNCNAT
+
!!$$!$#$#"#$$#$#!!"$!"$"$####$!#$"$$$$$!###!!#!""!$"####!!#"$"!!!#!$$$#"!"#$"!#!!##!$#$"$$$#!$!"$!#"!#
@r5667
GAAGAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCCTTTA
+
)&!)8'=G895->34>/.3G'@&DE!=874#15HB65D<=)-'401&FEB/3!!C,3F,
@r5668
CCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACG
+
B&=H;2-'B7GC!G=G%A5%&+'H!G@=B%3")&E(DB%)#C'902+#H@4A=10;4A-:4*1>E)80-/0G5,30?"+7<C"9<'9E"B?86'
@r5669
GGTTTNCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGC
+
>"A0:1+B4&3.8'1-#735+9>B/C/>B+@%AB$AHG-A46BB#,8D*E%)H=:DA-,*F8.G.HA2=@A67
@r5670
CAAATGTCATCGACGTTTTTATCCGGAAACTGCTGTCTGGCT
+
>"@).D/')1#!;-'>:@*BEH%4FH;9@BC"9!@.=(@)..
@r5671
TGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCA
+
H?+7#%:/HAE<&C/2$E(-E>*)+=)4E=((H09E"(8)E<-:#G<?!(FH;G>'7($9CH>4&
@r5672
TNAANAGGNGCCGCGGGTGCTCATGCCCACACAAGTGGTT
+
)"$*"&!*$+%('**'*'"!(!&(!'"!#!"%"*(&&(#&
@r5673
GAAATTCTTCGTCTATTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTNAAC
+
=F;;C)1=1>/.!51A?2EE6!D7;,H)@@0?6@E6#E>4,0%-(D5-,28*9'7((G8DE1"#32H?!6@>=AG:3A3((B$C0+)=*
@r5674
CAGTCGCAGTTCCCCCAGGCACTCCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGT
+
>B%,(6'C.&5:"9."D/*0!1D<&$#12DE@GE+$A'.>%?'-3+FACD6.<*6F(D<*8>:5?
@r5675
GCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCNCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGC
+
&)+!'$$+&!"&'++"$!$%(#*%&*()"'&&##"++&*('"*$'#&#)+%+*#!##)'+)!$#&'#$(%"#&&%(&"!"&%&+&+*(*%*
@r5676
CTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCT
+
>3$9?5$016/0<5B'AD!H+=>)=D&5*98C!=6(*"E*6
@r5677
CCTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTA
+
505B!714##G7F5%1*2A7#?E$7%*<AH'>'E/E-=:%E0);
@r5678
GNANCGGCCCATTCAACNGCGGTCTGTGGCTCCGGCCTGAACANTGAGCGAAGCCCGGCGCGGACAAAATGCCG
+
''""#)++$'!(&%%*%*'!%("!&#%""#")!+"""(+*(&%#*%"###$%*&(%&&'*$##+(!%(("(*!+
@r5679
NCAGACGAAGGGGACGGTGGTCAGGTTGNGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAG
+
&+1A+<8)>$!8>$%=2*(DD6(%F/9639'@#*:*-3<>A"#3%A#9)>%>.F9)+CH*)CC9=FA@1.A&6('%1='7D(H)&+C%'1D'A>)D<$,+(=2C=")0=0GA4B0
@r5680
TTGTCATAAAACAATTAAGTGAATTTATCATCGTCCACTTGAATCTNTGGTTCATTACGTCTTAACTCTTCATATTTAGAAANGAGGCTGATGAGTTCCATATTTG
+
FHC:)C=E3+5&H1G94G/8H,1).%;+$,.14$H38,C"HA6%$&:A7-(!0B#@A$DD83,+>G&+B3A)"D%@3:=C(4,!!95=#B9><*6H-!//#8&B/.
@r5681
TCGATGTGAGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACCGCTTCAGAAGTTCA
+
=+C)CG<;>+G&$2;66:")'5)1129!)%.H>F*<$A$/F=*E4=''BFD#!G15B/7C?-1E!D%/.&=C<=4C<E9
@r5682
CTGCAAGCTGCNTGGCCACGTCGGTGAACTGTGCAGGCAGCACACGCATGGCGGC
+
1%,D'*5BG3&;9&;0A:B*,B,37G;0!F.24,B9+$>F.)97A2E?=&A5)FB
@r5683
CGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGT
+
D?"@&68-7$*>$=,A;FC'=.E(1F-<GCA4C*2++5&D0HHB@,&=GDB>0
@r5684
ACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGNGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTAC
+
=*C2@#.>G*B7#)+7""EE>*GB2-=C!50E4@@4B!.:)D;30'?3;9$=2<+'A?(D$36%4$F.1:&/G&C"B?CE93E&=D5-"885:-7&
@r5685
ATCCTTTGTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGGCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTC
+
%36F,4G@(C#%%1G=!0D.E1&%'B'*@C(C15!=H-89H66>D4<3B&,,G"%-,F8+49,$4%'>&3@-!$;%6C9%$G-E47;)'FH@-A<EACAC>.241F#F&%&:-(;H.)*7F)7"H-.*F1=>?3'8(,;$51EB
@r5686
CCACCANCCGGGCAGTATGTTGCANGTAGCCGGGAANAAGCATCCGTTACCGCCGGACTGCCAAATGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTNGA
+
&&*''*#&#'%$&)*!&''**%*'))!"+$(+&**!#$+%($*$'!+(!$+)&)$%++*&!#*!)!$*+)(%*+$%&%+(''%)$##++(#!"!$&)'##'+$+*%*)'#+(+&$")#&#$%$'&(()$%*$+(%#%**"+'
@r5687
ATCAAACACGGAGTAGCCGTTATCCGNATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACTATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATC
+
'A(-8C9,?7,959D4&>+,E@,0.(BE,!#@8A2!G<E>).%7#$AE'F=B0=H58D+$.$:0"+:.%@3:,/@BA%,2#G1,$=8<'#)!>;)?1.B6$=%1'H'B22#431.:7(;,7?C2F.H?(G)<..>H2><3AF7-28,!A=@HD@G1+%7:?'3",3)>D;43EAG'@#:14:!B"C=%H=>.+C7+:'G*G-?B)52'$$B@$2F576)F9';%/F=/(+)B,DBCG#A.C,+@B5A='D;?C#>*9B>7,;@$".30H%*0:-DG4C61:!-+A79C@3:?>=4
@r5688
GCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTACAG
+
BG3#C-&&1$/<>(;B0C;860&*.B(3?#82E1=!H=D.!F>3*/3F*B@-1.!2?
@r5689
TTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTNATTACCTA
+
2;9$7G2!$;4B99B%495+3#?-EH?B=:D8=#2E%*<@5$0!G%D;7'A9*1D@62%+?.CG;D;G+C6#:<!,'/)%;+GG4F(G4GG&D5:H99"042$&=5A(D@+$<'7'6=3-)*3+08?>>%&G&
@r5690
TATCAGTTGCTGAATAAACGCGACGGGANTACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCG
+
(%$)+'!$)'+'"*)())&#$'"*($)#*!#!*()$%#!++((%)"%'&%#"%$*()$*#+%#!"&&"#**(*!%"*(+!+&)*%$*$*)#+++%+'+"'!)"*$*#*(##+%&'*'"$*'()"('$)"!%#$'%!)%%##"*+$+%(((!%&")&*!)
@r5691
AGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCNCCCTGGCAGAATTTTCTGCCGCCNTTGNCGAGGAAGCTGC
+
53ED%C;7B+>610.?$%(%%0EG8='+=-(,&;)@&(&!+F'5*!+695?%:(#0;B9/2>.&=11!2F+;<FF><43@5&C5$3;G?"E;@;>D=*1$65
@r5692
NNCACTNANTCCNGCNTNNGAGCAGGCAGGNAAACTNCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTNAGCGCCGGTGAGATAAACGGCAACTGCCGGNAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCANAANACGTCGCCCCGGTGTCATGCTTCNCCAGTGC
+
'&*!*"#*"**)"!*$!$"#%+"!!*"+%&'&!#+#%$'+"#(!!*%("$$"+&#)+*&!$%#')'(($+!"!"!%)!##*+$(#')"!(##*%))$$!+('((((!!'$#&'(++)&)*+'##%$+)&)%#&!!'#*$$%"*)"((+++)#&%%+#!&**%(+%)(!*)&!&*"+(#%*#(%'&*$%*"!!(#
@r5693
CGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCAT
+
'G8)328:70F50145C(5@<E!%9$D9*%>1&'6$F&9!%?=FC2%G
@r5694
CAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCACCATCACGCATCTGTNTCTGAATTTCATCACGGGCACCCTTGCGGGCCANGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCAC
+
%0A-508;B#673=6#C62,65:C&E6>/?2,C1;388/,.+@9/$-9&4$A'!8E84D#'D"",F&C?>%H'#;HCD3D251$2A*#G0;C,8+?#&=@C'?.".@&-;F=E91),F%,1F%C@@"4+09346#-'51D*52GG#%5?
@r5695
GGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCC
+
<@+CF)":,;,'<=66!!2"8AG;1@&!-::,!F(CC!;4='G"1B
@r5696
GCATCAGGTCTTTCCTTCGAAGGGGATCCNCCTACCTTTCACGAGTTNCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCG
+
G?B6$@'EF368(*039<FD>*F>A*948H;(6:GF(!D!6C.=%&H+;<!A<2G<DA"=3GH!,*62:>?7;00+DE>A33&G7;,2
@r5697
CAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCAAACAGGGGGATGATGCGTGGCACNAATTACGGCTCGGCGTCATC
+
@"0;&.:A<=H8.%AD%-,ABE,8$6B53,&F<7,6AB>)3)5H?)-=4:A>4-60*FG@8&%,$$?D0-$<9!8A'G-?;8<A=4%CA)4;75C':7%40;.%6<8=?'
@r5698
TATCGGTGCTCATGCCCATTCTTTCAGNATNGGTTGACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCNAAAACATTGCATTTAACTAT
+
?G@&C''75#<"6F";"$9/4EC1?,,3(:$A0=.-.1*&H+2/E<F$:1?G@5,83GDGG/8*<(>H$:<'+%B#D.66!32='01)+*9(90F@0=4+@&!H4DA>,
@r5699
CNCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAAT
+
)!&3GH#<??#)5&4=F<+><4#@'G.?/=:84<-204*+>%@((-4/=?:D(G#304EC++/57G"+#+FD:%D'29*-%?'G3
@r5700
AATGAGCAGTGCAGNTAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACA
+
G4"HEFAF>4=2)86E'GEEH3G="G+A76C0,1)?/3DE875(D(*7!8E(=B5=-<5A,E':,#8E
@r5701
ATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGAT
+
0(@>.+5;<CH&%(C;<9-.:H8E>4$F).<,CFB-=E6-8,=;)&!B+%*#(>HF+B10':"E57A1"?A>G<=$3A9B
@r5702
TGCCGGTCATNCCACCGGCCCCAATGGCTGCCCCCCATGCTGCAA
+
+0+(9@5<;>8>@+C0=4+<4.3>F),4;),/D&+,0$4,6?/)&
@r5703
TTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCT
+
+)'$!"#*+)#+"('$"')#+!&(%)$!%)$("+)+#%$&*+&#%)""%"')&#+++$$$%
@r5704
GCGCCAGCGCACCGGTCGCCACCGCNAGCGNGGTGGCCCCCACCATCGGCAGGGTGATC
+
!+!(+!!*"+*"((+*(!(%*!#$*")+#'&"*#*&$%&&)%$&'$+*+&(&!%+'$$+
@r5705
AACCGAAATCACGNACGTAGAAAGCGCACTAAATCCGATAGACNTTACAGTGCTGGCTGAACACCACAAACAGATTGAAAGCAACCTGCA
+
+.%@<G@7#E5(EFFC7'5!8@,E'C<@A$!=:99C?EF0(20>?<8E&@"-/D5E?G2E&,H#."*/(2>@D3>G'+HA.6!FG=<7%.
@r5706
CTATTAAGANANCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTNAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATNTGTTGCCCCTAAGACCTTTAATATATCGCC
+
*)(#!(&"!)+!(%%'"))(()'&'(&!"++(!&$&!%*!""+**$")$+!)##%+*+###"))&))+'!#(#'#+)&'!#""$'$**%+"$"$""(&*!*'!!*+!#(#("%'*$""$'&"%*+*"$"+%*)((#"**""#!$&"$"&%'*))'%"(#'&&%'$!)&**)&%%)"#"**$*%&*'$'(*
@r5707
AAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAA
+
-;D,D-/-GA6&9@@4*"6=DFC9.0*#C=A@*$'91&$##!/44H-(/2-69B:EB3C-AC/9:BC/;&2-A9
@r5708
CGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCC
+
/F:.,<)8B=&0&#%-+)<=1FG-$7&0/A434A4BE04B@'#=A&H3=1#!0F"3(!C5D*;1%69%:<<&&>C8,&%<<H6%$<@<B(!BDH.219:$,':C0;*+*=D>G?4>::E9CE+A($)F46-'H59>%GF"@B(6F2":2"D?
@r5709
GTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGNCCGCGCAGATGA
+
@5'HF,AA/='"@)G9)7#4B-=%A!#'%12)2-HAF.BA/,&>==GH.=2
@r5710
TTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAACCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGAC
+
A8.G5.5+@?&61F37?:%8=G)+H#9?5/E&9-"$347F(<)!9'#B$@,?FBF/0)"#=%&->*E/2?*-C;2%%?EGF)0AB
@r5711
CGTATCGCATTTATTGACCCGGCAAACGGGAATGACACGCCGATGTTTGTGGCGCAGGGCAACCAGATATT
+
7?3#46!@13?0=%G=1F27/A%C=!E(($&2G'*.+$5#:*C9+,E,-D:$<B6%/;2ADBD+#+D;7D<
@r5712
CGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAA
+
&,'2,C?C,.<7=2;*%%?EBE$8.D0=#F86<"":H>AG459(F+
@r5713
AGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATANT
+
/D-8>"<H1-BFB27E)/1*;<!*D>C+.!>G*51&,=EC<A!5&;:D",H#-H&/*+C.:<D*6>;*76*>257*A0>3!:8B;9,4E?&8F2E!)(C;B:8HC0(EA,!5*/#7"&;HF5.-B"@??.;*E03)*$5>D;+0@H?;3%)>6@46:A>7$F9);31)H)83CA8""5:,$'E:(@<DE@9/*C:B+<-2-#'&(D@-1!$.>=B!1D($8@C:42"@6#,&<>35&0C37@)+C-,@>#7:%%$80;>:%-0!&<*!8*"B;'#:0<F3470F(+%=H0G25>E/#H<0/(B;2?*4B2?HBBEA6(AB&//&+:4GG?9
@r5714
TGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTCCCGGATTAATCTGTATACCTGCACTCCACGCCACTGNGGTATGCCGCATTGCACTTTNGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCC
+
-.$/<79)DF17)<=6?D=?'54*+BD9>(3(!6G@83)H>C-!?96)F4</7>@0CC#B/;3D$C;''@,0,=E;%"A:"AHA+D95=6HC98*2H1427'F;-F7>+%>"<(9B2D%8#>)E6%G'*0?,E!2H%D9#)8!3!.2(:!A<%C#2(!@==30.(+@B*(;$)69>+@::0A:(.G79%1+>1H),2672EE:9=*G2@.GH&19,?&;?7'2?H*55H:..F*!4D1F+$D7C9+.C%(D$A!B804!<:"3G-4$E!B)*0'4?19!;>?E+."0H/%+A!@6":H(G
@r5715
CTTGCGCTAANNCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTACGTAGTCCGTTT
+
E4;A/EH,':E;&4!(C*60EGCE+/<G14=<!A.!*!"6*23)$49@#E6B@B.'=AH0-HG(D;"(/GF'0$4/E$#@+D:7:+>AF$#=;453,4
@r5716
GCTAGCAATTAATGTGCATCGATTATCAGNTATTGCCAGCGCCAGATNTAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCAAAACGATAAAGTGCGATCAGTAATTCAAAACCTTACAGAAGAGCAAT
+
+<56:1GA'G6(9B,'&#0936B;"+1,C#=E.9%0.&(""%@A>H15$#E8DE-9?59&9H)8'#(#+B96;C1(D,G)EH+;%&CE)%?.$H;&!*6?HGBD4?;!A:0'/$$B:E'@;)+0:/%/>?F
@r5717
AGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCANTCGGCATACTCCGTGGATGACATCC
+
+>'E)>52..:"?&-.9B+9*%==A6C02#;?"+E!>H:&*B*A,/6),(7?+?''!;D,$<7A<GD
@r5718
CACACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTNTCTGTTTT
+
3-33<#?$@AA.F+8/&B&)4#>/'#C>9B1.2A*G8F=B#C65E'.&C6D@63F8-:E':C=D<&G5;8GC.&%CD.C,?FH4-
@r5719
NTTNGTCNAGCNCAANCNCGANATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTATTTCGCGTCACCCACATGCTGTACTGCACCT
+
!%'!#"(##$%*%#$"'$***%+&"*))%#%*'+&&+&$(+$*"#"&*!$$!%)'&''*"+"&%!*"#&&"%!!*#*$)*)%#$""!"$!'!*%$"$!+'&)%"&$'#+&)
@r5720
ATATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAN
+
C1+'%/+B@6<F"/9GA4,3=$@AE;)%H,&%$31"@6<?B6
@r5721
GGCACAGTTAAGGATTANTTATCAGGAGTAATTATGCGGAAC
+
G<67(>2$632)5$)G"9!F3=5:EE=)<(=/>@;6)H>!/A
@r5722
CGCCCCGACGATGATGCGGGCTTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACC
+
)'!(+)+$%'!%"'(")()!$(!(*)+*)+%&%$)%""$#(#*"*)#))'(((($#($+#$+%"*!#!'**'*)!$""+&%&%"$&'
@r5723
TTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCC
+
"C(,E*F:>C@:C/-#%G@2#H0'G4'8CC>0)1>),%C?4-F
@r5724
ATGTTGGAGTTTAGTGTTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAATATAAGGCATTCCTACGAGCAGATGGTTGGAATGACTATTCCCTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTAT
+
=('766(H69A#H1'&+7B9%6<H,A5)D=A9&(>62>E/B%./C60)<361*3!*-1D?C?(882HB;;B*649-(CF'5=.$=217>E%6H1@BBB<G>2$."+/6E/C)"C?75FA>;FF6EF(A4F4',3H!5>7>-&C/B=:+D,,;H)";!E+D$&E1E27$++F!A;@F%G8'&ADC&;$(F<-?,A<:/)$'"0'.
@r5725
CTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAA
+
$*+'$&*)('(#"$%$)$$(('*+*'&&'"''*)!"**(%(*#+#*""'+"+$%$!"*')+%)!('("'"$%&%#)!*&("%(#*$%##)$&&$(#"#'"*$$#*%*'(%'&!'%*&#!#)#$(*')**"&"*($%+%(##&&&+&)("!#+#"$%&!)$%'#&)(%'$!&+$!$!$#*!&(%"&++(#)($#%(&)!$("&(&*'*!")"'+$$!'##*$"*)+!!#!$'!+(#)**"%("#("$($&*!%'&"#$$+(%(+((+&*$*")")$!)'&"(&'&!%#!
@r5726
GTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTC
+
D:-29AAC-.:$!)H<9()*5G(H(<3#;.,1@952DA=!C+?&3@(2G@B."5-=@(G:E:EB7%@7(:&(@D/.:
@r5727
TATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGGGTA
+
4HA&G>713<@+B?,3#/EA<#6&$B6:@3:>%,"G5,B!?
@r5728
CGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCG
+
20B8!686*?,CCD%);&/#BG5$A,#)$F%36=;2A--41F=5H:;B);9
@r5729
TAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTAT
+
B&%.(CGC789(B&8'!F$+&EH*9#5AB"$*#")!CD8.>03'D0?$#8#2+&1>.21/E*!()4B4,2DH)<?'DH93?!-2G)E8E6*0+<>8<%'"79,=
@r5730
GGTTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGC
+
A'.@)B/F&@5F237*&2E!6,$>8@62/4325%<;$*#3%(4?",&720"-H+)7&E4-E>A0)/H.
@r5731
AAGATGCTATGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTNCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACAGCTGAACGGCGTGCGA
+
$"2(6CF(E4)2,E19"')<<$1?';4A@:-A3A*B?9@":7"/#9/3,6>H1<'=@A-$4,#'3$C>,$!6%9>D21;7#(=*/'';%!D53*(GH'B,1DE((/#C.2$=F;.*$5!G<%"6;52?&3A@$-<44>5@,F9C$4
@r5732
TTAGATATTTNTCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGGCGCCTTA
+
2F1>7:4-,/=<)!@'*+!'"03(/77G%#A,E'F#G'+:!">2F.A,/@2'';<@=?&*>,?0)B&G2.(<=/.+51,$%'C'A09@:<D2<:
@r5733
ATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAGTATGTANAATCGGTAGC
+
<C@41=6!C?7B?A<60=?,F*<;*E8B@%E;-847?GB0$@&)<413?.5F!6?'))@A4BA+3>F2>;CH;7@C0-!#-$AB"H#09>D@8
@r5734
NTGCCGGTTTGTTNTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAACGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTG
+
.:/:/=B7#2'-5!H+9(8)-$-*@B?:D(DE1,!%+%"#B,<&G>(+4'921=@B$(-@?4A0FB07-1"?-GG"26&,35!@86&G*H90#!G?(1B*H!#B3@CD'&65:!@9,)3G1E$:ECC428;B)0-F,2@57A*2DAF6?$/B1#HGH!.1<GA-%
@r5735
TTTATTAACACGGTGTTATCGTTTTCTAACACGATGTNAATATTATCTGTGGCTAGATAG
+
89,9+3+4D=-:+F%),7%1&";:)%&2&G3-<H6630D&A"*8=B*=*3125E6D6!A#
@r5736
TNGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGGACGAATCGCTTGGTGTACCTCA
+
7+F79-2"...7GB8%19479E'DAC6<3+!(+D)1*.B705*.@D++7;4<6**8H4)ED**H@)63-.0?.CD$=5B>66=A"?.;<7;4-/""6-,E1423<(-/?0:=(A%H>$>+:+,F1E7*3%B%9/D;@>%1&3<A5914?15C.:/1,H(,'*FD;8*&.7C;
@r5737
NTTGNTNNGCTTGGAATCAGGTTTGTNCCAATACCAGTAGAAACAGACGANGAATTTCATACNTTA
+
!$)'!'"%"+)%"(*%($&#&()"#!)(#(!#"%"!*%%+(&&!&(+%"'#&"$%(!#*&$#$'!&
@r5738
CACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAG
+
50*/18?.(9#0(5=GH#F*&.83C2?#36)$D3!3,$D;),.&'C<G*/#?>FCE.,F,:@+DG)'G(6"44"FB()1"*@/%55/;>DD+/-E%=A-1><46C(';><#%:@>1DGA+9="
@r5739
TCCGTCAGCTCGACTTTTNCCAGCAGCTCCTTGCCGAGATG
+
(,='/-(:18;=H;$H,0?1:2433:&,=F9-:"6A")D"1
@r5740
GTCCTGTCTGNCCAGGTCTCCAGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGG
+
3&?HD2/?0'$&50A@&)@3GH;+8(&?"=0!4<>G9G.C83;A+=!@E?:30C+$&%3B+E$,9G4@2G7><(C4H9,5;*/$'1HH0EC<0>;%@/C2D3,/3)=G6")*512H'831+"4H=4DC6+08HG::*5A@2C3')<4G-/@!<7A,'+.013</FC?1=G5G**600A3D1F7+.D>'E43%.4/3,1&B$D)E$!D*;%"(79B8E<H07'6F-;&G6!)8)D>9)');52'#,0$BC!9D3?H&G+=0-GH--%6D9,1!'8840,(D7B!82
@r5741
NAANCAAAACNTTATAACGCCGCATTNCTTGCAAAAATTCTCNAAGTTAGCGTTGAAGAATTTAGCNCTTCAATCGCCAGAGAAATCTACGAGATGTATGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCANGTTCAGGCAGGGATGTTCTCACCTGAGCTTAGAACCTTTACCAAAGGTGATGCGGAGA
+
%"'"%""*!%)*(+"!$$(%$!!##'(%*&##+''('!%!&('&#'!'+'!*'&')#&(%*!(%*('+(+""**!#+"+#&')"*&#*&%'#%%(*$""&)""&!&!*")***)*"%(+$#(%*%+)#$)+%%&!!''"&#*#("$#*!+++!))(%+'&'+"*#)*(#'+&$!"&'*+&%#)&('"$%#"!#'+!'(+$!%"+!#)%$$%&(+#%*
@r5742
TGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGT
+
%/"2E6#0)5F:.8:ED$7!';#';915-&A>G8CCF)@:?'3B3%@:@:'=@%B1&DC=@%=,H13(H+7FF@E5E2H2E5"8";"DE?!>;<GB&C541D<@C)$9"78"7<)$*/G?6($4#(:2:HC:;5'#"09C)D<!5E+AF)(?1./1E"#1G:#4*F,EA"A$(&6D$#-/<#>=;*6AB9H;.<?6#!)"-'#=6A$FE47A;?E?
@r5743
CAAATTCTTCTTCCATATATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTACCCACATCAGGCTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTNATGNGTATAGAAATGGATCCACTCGTTA
+
',3-A:&G99-9+@>/:BE*<)+5+69A'/BB0.7'+A)57E%F>06C'*F+2B#G-3&>3+"(<<E%#!3.E58*99G(9-C74#,D&9,!*%GCA:FF+)9@F?G$',1A692A"$A(<$F&.=E)#H9>?+'.75E)H#-0G1*?)7(+14')F/80'*82#8?&22%
@r5744
GCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAA
+
8G2B*AG8!8G)1.7DF9<9!39880030.6+!44H:&5440
@r5745
ACACGTCGTATGCAGGAACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATCTTTTGCATGAGAGAATTTGTACCACCTCCCAACGACCATCTATGACTGTACGCCACTNTCCCTAGGACTGCTATGTGCC
+
-$,;C@A=(C&$->!<-/)0F/-5<BE=3B8A"#,-5"05<D#)>@80(0$CGD<H.@*0@"&48C+3F+FG$#*7@$@3%H;G+!A<<7H5;>?"#9B>5F8!+A2!!.F$D-;@F?.5$"?BAFD?=B<56?(+3246>0H4.4<A<+@D!1##45+?+&4)9&?%9E%,8
@r5746
CCCGTTTCATCGCGGCACTCNGGCGACACTCCTTAAAAACCAGGTTCGTGC
+
ECB@9'&)D/E:,-D70'?02/F5%%7@C3!1'.=83@1#7AC=)%79(!2
@r5747
ATGCGATACGATTGCCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCC
+
B*-A$D=CF7!0EHD'2>59;0>H&5,H2,*5E<%0$F4B*81DG:(H!2(5E
@r5748
TGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGC
+
C-<%/)%)CC3+/9?=?('F?1.+G8":=#%/HC;5/="!(G=&D&(7$-3;<+>G0+5BC(83@.#"B7:3@=(8-E$:?2),E0
@r5749
CAGCATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTAATGCTCACCTGCTGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGNTNGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCNGATAC
+
<.$:6H7/$&E<1.F2)A3$;7H1.0:G@G2?C4H>8G;!;%90*B>FA/>B.&G3E)>9#7E(2G>D'A0+/?&7871&+*;B:%H&%"942.D>HH-(?%8!$*)#:*&%52.3;F5DH=$%,0;4F2+@072:E2A:9E6#-H98=(!@E7H5.7-.FB/,-!8B&;%;7ED3G>.C,D?"9<+?'$/4?B'9/E4)"D"!=H789-!!CE>/>7!D>:C=/$'(0E'$D<F9&BH#G2E&#0.E1'C6/.3<3<?/-#$,98C&-(?=C,<&B"65&'++>)D($#D".C6*91A)=-98(01!CG:(:A$:16)1C42:E$GC0>@!+@--2.+-DE/H/FH9-;:G)>-
@r5750
TTTGANNTCNTNGNTTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGTTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTANACGGGCGCGGCGGCAGGTTACCCATCAGCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGNTGATGTCTTTTTCCGTCACCCAGCCTCCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTNCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAG
+
(*(#''#%&"!#)'+$+()##""+")%(+!)#$#"&%"$)')&$(($'%(!#+*##*"(!##+$*($%")'#)(!&$*&!)%+()"$%!'+%!)+")'''"+('#+&!&((%"$#*%($*'$)"+'&$)+(#$$%+$*))($!&+$++"$*$&')(*#!%"+(*%$#*$')*)""'$($(%'#%'%!%%(('(&)*(%'+("'!"'&(""&'#*%("'!%$!((+)('+((+$%#&)"*'&"++$!$(%#('"!%'$'")$'*!("')"$&"*!#&*(&%!()"**+(+)#%(#++'&%!&*'(%*()+$"$(#!*)*$&"($"!'#&#'!'$&%*##%!#'#)%!'')(%+)(#"$%#$!'$+""'**%)&#)%*)*$
@r5751
CCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAACAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGA
+
G63*,<;F"(4>C+?;F-C$1E;<3:C,=<#F'/2=C<E2%-2EHC((CH8E98;)F?4E;#%,6!D""(;@D7C!@/:'-8,(BB1$%'E%AB"-%%-C1B2&3<82+&0<4A'$.4>'?)>=53'@/;G:54-;4B1-2%"E8%F&3A%:G0>0-/7=E5>+<)77A#1!,./G37#CHC/=.,$;/#=*
@r5752
NCNCNTNGANNTNGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCNGATGGCGGTTT
+
(")#")')%!!$#++)(!(*$+"!##**&$"&&+&"(()%+**)&*(+%$(*!%*)("$%&%!(%$%$)#&*&&#"
@r5753
CTTCGAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGNGCGTAGG
+
;'*2!%)E&%*6D42F7"E$75A:G)D-1FE0>7'=(H#.<#9"F#,6&<3><B6<5%5++#>5FB"GB+#7*D>D<2D"*H*,+)?)&$:EA;5:/,
@r5754
GACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTC
+
1(26?,A"B$';$%)2%.1-DG%7?0G2F@"*)G?&$97H&?(A7E#<E6!"/B8G#8>=D"+65D+'=:835&@1F--6B->A2D=C?G&<$(F,81GD7!2&9+.6)/B0>
@r5755
TCTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCAAACCGCGCCGGGCTGTGGCTGATTAAAANAGAACTGCTGGAAACNCAGACCGTGGATNTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATC
+
*$*;5=H<$+9,E@F97)A+#C$9@:(=62+.:@H5,37*F$@H6%?/67CC8!='9,@F"=)E.@14&:<C8+3*.B6D3&52B?#.5?"/7(%"$;2F+";5CG'='F-*5>.6'?D%=2563%-C!80/'("4>*+#.:8//1!+./-GC(%6,A+111E8EGGA%B51-EG)!30*5E2$*B!$<24(,=6;
@r5756
GCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCAGATAGAGATTCTGGCTGTTACGCCACCAGTCATCC
+
68AGA5)+:''52B4>)$4#.@%!'CA(F(3"/,-G'").(,(G?D/1G:=5,:672$?12FA-F8/080</(6=174#G*=""
@r5757
NCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGNGGAATGTGATTAATTCCAGGCATNCAA
+
(=;$#H'E;BG#$G28!#%@3:BA%6C(1(E<%;9A3)5"#9$19'2/736&G+,<2?A!6)3C2!DB!9+:D6#!5
@r5758
CTNGCGCCCAGCCACATTCTTCCTCGGNACATAATCTCCTTTGGC
+
!*'"$&+)#+)'#$%+*$!*)**&&"(+()"&#)$(#+%*!)%))
@r5759
GACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGT
+
644*24?'"A7)'#+?2(1-$??9;%C/<7/@3<5C*G+5F,(
@r5760
CCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCT
+
<696G3.G:8'0#F.4$G2?F%<@"0.)/D@.DAF?7E<B-$5,F/0:F;>=BH##,DHA5E)D&E;B8H)G01&H21&'92)3G")BC:E/5<0<$3?G&8,B;&>3"B(8/D/569!C.,B7%<28;9!%@:
@r5761
NNGNNGGCAAACGTATACGGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAAC
+
""*!#)+#%$"&+*')+&!&&"##"+!"#+$"%(('*%'%"()'++$*"$$')#((""&$
@r5762
TCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTTGCCAGAATCGC
+
-)66?0/'-B9D3'.%))1E04;H6;#!37C"/E9@="/@#6020D1#+:>1HDB!A)$5=0C=/F-)?7
@r5763
GTTTCGCTACTNTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGNTTTCTTTCCCGTTCATCCAGCA
+
+("21)#5>%6>77-$:3#$&<5DFB6<(,EF#C9)F'9E88D=!$!1*+)+.A.G$3$!!->@>,!?/!E60;H'%5)DF)@C
@r5764
CTCGACACNANAAANNTNNGTNTNANNANCTANACNGNGCNGCNTCANNNCTNATT
+
$!$!#$"#!""!##!!#!"!#!$!$$###$#""#"!$!$!"$#""##"""##!#"$
@r5765
GANGGGCAAGAGCTTTAGCCAGAANTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTNCACGTANAACTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCA
+
!)!*))&+))))$*$$(&""'%&(!+&)+%!*$"&#+*)&+%&*#+++(&'!'%!'+()&&(%#$++&"$$($&##*%(()*#&)$&("*##%#(%+&"'%(%+()*"$"*)(+$!+%+&"&''#(#%(%)+!($#'!)'($!*&#$(##*"!#('&"&%$()(#!%#*)%#%*&+"++''#%#$'"%((&$&!)''*%))$%"%"(!!)!*$+!+%&!)#**'$!'%'*+$%""%$%"(#%&**"'
@r5766
CGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCNCACCACGCATTGCTTGTGAATATTGNGTTCAT
+
C#%)4&B&&"-0F+/BA.G)GC'#.*08G>C@/!3?$*E/'D%5<'HC.0>A<47GG(0B&'.)H(;"E?
@r5767
TGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCG
+
6",C"9DD)8F0@-65)>D&7DA*D0'+(D<>*B-#$;5&C92+G0*2;"0BA(,/5>:?GAD;-;H/#7.?30?'9%A:@(!9*,4>C>774/&7;4$B
@r5768
AAAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAAT
+
@D1(DE3?=B"A,F/=2!C*7?*C<?9D"'""./EBCA9>5(+.;>!*>%8(:.
@r5769
GCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCNCAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTG
+
2.6>G8&%3(C4@&=FHH'?.&'A?B@)89;5*2)"$74'43(;;/&5)C;4=5:*E7!4492.7)=E8&&EE>FA>CD7%<(?2=F6H%)(:$G9&+=6'A.9..92=,@.-G4H%"(;)FC@>+8
@r5770
NCNGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCAT
+
%'!'&)%+)#)$!()&%%'#%!'(&!%"&*''%*'"'+(#(*)($+)'"$")#'%%'&+#)$&+#"#*+*&+($)('$!)$$&)#%#((&"'!'#)&)&')$"*(""
@r5771
NAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGTCGGTGCCC
+
2EFE62GD35G5<%B7=#9G"+;#F6.$8E$:0(2H;?)2#.1<9%G'7:4G<<H
@r5772
NTNCGNTGNATTTGANAANTCAGGAGTGGAACGCACGCCAGCGACGTCCAAGAAGCCTTGAAAC
+
$&#*&"($"%%*!))!&!+!&$(#!'&+"($))"+&'%!$+"*)'%*!)!!&"%+!!(#'!"+%
@r5773
TNNTNTNGANNGGGCAGACGCTGACGTTCGTGTAGGACCGACCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGANGGC
+
%)"*#'!(&%#&)+#()&*!)&#*'+*)+)+)"((!&*#(#&&)'*$+!'##"$+#&"!%#!#('"##'(&&#$"&&#+"""))(%%#%'(($*"$)*
@r5774
GCGACGGGCAGGTAAAGACGTGCATNACGTTTTCNTGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCG
+
5G'!@<57:"0%=27""0/F58<A(1E@/A+>/4/9!!C96E0A/G9.904B&2G=A)*FFA5/)+H<:-7@?6!06*,.,:'5E62,+8B-+3<F7-;>.=B+66BEF.!!8
@r5775
AGATGGNNCTGTNGGNNTCCGNCNTTGCCGGATCATTCTTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATT
+
"%((!()$*&*!)#*%!'*$)("#++'"##!(+&*)$&+#'$!*#"(&&#**$!"+"+%+$$$"(!#+'!)#+$#&%&+"
@r5776
TTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAANACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGANNGGTTGAA
+
=@4:)E;!D0'5G72D-:)H:7DH>-!D6%(B,&15"7H:'=4;=%+?7-8)="4G69%;@+B>92$8;@-=?+0;=37:1&;0;)!>$<&;E;"6<%<&)@,?:1??/#&?;?/<=*G-%4:HE;*?3D"-347*<0
@r5777
AANGCGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGGNCTGTGACGATGCTAGGGATCCCAAACCTCACCCAACCCACATGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAACATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTATTGAATA
+
%*!&&)($&+'+$(!&&%+*')(()''!*#+##$"(%#%%++#'+$$$*!"&&%'('(*%#%(#(*(#!&(++$!!'!*(#")"$+)*)%%#*$%$*%$''"'"%!"'')'%$+&*!#&*!&$$"'&$&#*%*)#+#'&+'%%*'#!##"&$*$'+)&%"'*&+"+$!))(($#$#)'"$)'$)#("&"%)&*!**!*#+(!'%%&"#'(%"%(+"((%$+')++%##'"('##$(#&#&)'(*)"'*$*+%(*(#!"!)#
@r5778
CTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAANCACCTGGCTCAACAGCCNGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAACCTGTTGGTGCGGTCATGGAATTACNT
+
**(+*!%"(+&%'%+%()+%++$$"#)$('&)%*&(&(")$(!%)+$##!#%!##"#)$%)'&%##("#!&&&+&&)&")()""$&%&#%+$)+)$#%))'(%""*$(#$"#$%*++$+*++&)*'()+))&"#*))%$!#%(('#'%+(*%)""&
@r5779
AGCCCNCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCNGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACT
+
2F-@B-3%A#$A(.D7*"@+C!=CG:3'%>5C4,%,F"#6&7&;,="(!;51$.)C'5B%:79<12H"(H>$,-3;A<14-/9C**1/>>(?!?".#@
@r5780
TCACCGTGACCGATGACGCTCCNTTTGATCGCCAGATAGTGGTG
+
DFB(-)%8%3GB43)!:(0);;%!6";%A/*A+#"(<@*A(&C6
@r5781
ATCTACCCAGAAATTTTCCTCACCGATGGNCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCCGACAAACAGGGACGGGNTNG
+
&,DH-<2?;B-=/2>..H3H+=+6,$&)$3!@A8B%E>#5:(">-'-$9-AF$*/G1F6,:&H3/-+;*7D65(>,5-/@A==@3:%!0C("
@r5782
CAAAAAAGGTCTTGAGCAGGCCNTAGAAAACCTCAGCCGTATCAGTAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCC
+
0'+=D9!%0*!;G,:/';H9#/BE%3-)5F"$0@,D;9+'%&.B@)(@/4-*.'%:&2>9$3/1;BG:BDB?:<3,.7)&08=$5!&
@r5783
GTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGG
+
($4@E.)#3?-)<F,(;75,?7=('!!?C<:5<C/<G9F,9H>B.-DA6>#';4%
@r5784
TGAAGCCCGCTGCCAGAAAAATGCNTTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAANTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCGCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGNTAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTA
+
<#(3%;?+FA:>.+(5-1:0:(4%:F-6<6!(5(*(;#'0AGD%'B,$8:%&$/H,,>H!FA/:55<C36#.$0F00B/3=26>'527(;H%0!7C8<-(":@F4A9,E(/G:/-D<D'5EB6/>@=(BF5#>37**=E7B2+.2C%*A8C4H/%H<?:"#*8E3:<9D4).%!D+'58$/4G#&-*6@#9E&81($>8(DD?>7(1A01!?H1'678/F(@!G9D29%#9"F"C==1>'8=&CD5?E(1E?$..>3C-8D@2>GB4EA.9:8&"&07$(B8$((.D;C<87(9%:!G3;B'>@8;3,?A?D72(D74#@#8$2+A&
@r5785
CACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGCTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGATCGATGAACTGATACCGGGGTTGCT
+
$FC!4C8#&5H<%;H><H:137H(1!C-3)8*E%?E<:#2.5*C*95-6,>0<;&.$A'G?;7:G3/02+H(>9B+/0(#-!**,/++=&6"-96/E!H&,645%E:1>/?7-AH8)%,+&&>+$#.<'F1@H>)8927H8;12153><+=**3#6&AH#F)93310%1E(029*;(>H)G8-(A1"@9GC%B2%=?==B4)0!#28(3/CE2F#%=:B-4;>D,>0?"
@r5786
GCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGA
+
G6**&<)!FF.).7>E#:!6<$5:?>/-(GB&!G',C<'7EC/+6'7>*9@H4"->?$58%;-B),+<'(?#B>!)E?2H!A57!&$+%9<1>F&6:3:?HCH,:4G7?#!70$#1F+&.%5/5.=(D'D<""C:EA+)4"E*F(6@"$A5;-F33'<D*F(8'D-*6&$4C<4,4'.7;!B(H?45H'<<,#42FD=+:+&E
@r5787
GATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGNGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATC
+
-H0>7'28FCA$,(+:<0><9'E4?$GB!:80FE09+?+3/F7)):.<B7"52&5H>C2F$@0;$+>EAA:!"+C
@r5788
CTNGCTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGNGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCA
+
()!*#+*$$+%'$$"$&(()#!)")"%&#+"*"!*+""))!"$(&%&*!$$+(##!$&+%)!(#%"''#))''#&#$+!'#%!%#
@r5789
TANCAATGGGTATTNGCAAANTTNATNTACTGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAA
+
((')(((*%#**%#!#&'"(#*)$"%&*#('+%**!#*(#*)!+*')!"%&)#))$%&'+)%&)+"%'+"*'(++&#("("("&+*")%%#%"%(""'"'**$+!%+#+"+'(#("+'%#*(*&'!%)"($'%%#""&&"%!'+)*"*))("(*&'!"#+)+'%(++#"#)&#("')(+###!+$!#'&%'&&#%#&$&#
@r5790
GGATGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAA
+
)-2<-9C2>(/.<(0:446,8A'2?63>5<G.8:G9;*8E(#09;1&2'9
@r5791
TGATAANGGTTGCATGTACTAAGGAGGTTNTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAA
+
DHC0'8$*50F&B-*,F2H)@5#4F/''-89'=4!3(106F=6.GH+D<&752DFA3C1&0>-<$=)%&67@+!=D(:-;
@r5792
TGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAANCCAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCTGCCACAAATTTTGGCTGCATCGAAAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGT
+
%"+#!#%'!$"''*'"!%$"#$$$$"+!&*%!*&$%*#+$&'#&%+'"&#*$)"$!"'"(&(#&'++#%%"*!#$%'(+)$#"')+*#!($#*"&)(!)#"$""(*%&#("("*&$*'!!!#"%##'&)$#+!+&*''*''(+*"#("#%('%'$%&$+&)$))+&'!*#**$!&*&%+)+))()"!'!'"+()((*+*%%&$*+#+#&((***)&!#&&")
@r5793
CAGATGCGTCAGCGTGATGTTGCTGCGCTCGANGCAAAATACACGAAGGAGTNAGCTGATGCTAAAGCTGAAAATGATGC
+
GB27?'13@!)=4AD:"<5G4F03/)"H60;A4(:;<?;7+=/:72;&,C%&D?BHF@D*7'102=1@4G=D#9GF>H8$
@r5794
TTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCNCATTACACAAA
+
+*!*!)&((+((""(()!&)#+"*(&$!(+(!'%)*+'*(&&!)#"'&&!*#"$')(&++)"+!$)!&*%+!""(('%($$#&#+%*(#$")%%")
@r5795
NCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCNTTTTTCTTTTGTAATAGTGNCTTTTGTGT
+
!#$+')'##($(!($%*+%*$+$'&"$$*""#%)!)()#&+#)+#*#(('(()%+&*)+!!%()"&+#+%"'!#!+$"$*&+'"""*("""(**%$*"%'#&+#+'!)'($!'!"&$%)')!*)()
@r5796
ATTCAAAACTCGCAAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGGTACGTCATAAAGACATGATTCAATG
+
-1>>"D',B9+:D74=H*>%@32'F"9:,D:D&<1'2F8#E&-1(#=C5?9#$E0)'E*/EE38.;#E%!=&,/!GBG')=*14'@'
@r5797
TTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGC
+
95.4@>A-#B+.)>@6+G<3?/B!21E6"<-"2@1D$'&!-$)F+:)&3AE=H?G&E58%0A21%*EH(G4@.-G0@0/!3,2(!=;?+.;8D:3E+2#6*9;<1D3;8B'+,:=924%F+>$<31C-47,GE?&F7$
@r5798
AGACCTTTTCCATGAATTGGTAACTCCATCGATTGTGCTGGAACTGCTG
+
1,@3GF$7H%!#!D:HE%:./B>,;4A8EE@&.)=:39+'*<G+*A")<
@r5799
AAATCCCCAGTCGTCATGCATTGCCTGCTNTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCT
+
G*@7;1D<1.!H9)8.(2@%*&5/=B4/7*6$&0&-=$E3D;*&H?.<$>F!$6#/650D145E>492&)(+!7HH58-8C-!00470"GE55/*"*&#/1!&AHC
@r5800
CCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTNNTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGCGCCTGNCGGCCCCCACCATTACCAGCGGCGGCAATCCTC
+
.G862!@7=%2;&'20E#@8";1HC(9H5.%104+8+$+6",'?D?G!=@23"@ACBE7#+!$%@(C;%CB6%-2=(@G<,>;@"&1$BFAH4D@,F;@:1+A25*6!)26,-F:A;23>BD<;32)"1>)7F1#D?$'A45&8G!!&825,,*"E(.?74HD7%A?<818/*?"A@(+3*/DD*.E)4',3+-?7C)4$:C)$DH617:/$#+8="FA30G'H@GGE":;,=;(.!-:!.58%">
@r5801
CCAGCGGAAGGTCTTCATCGTNCACCTCCGGAGAACAGGCCACNATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCNTGCGGGCCATGTCTTAC
+
+(+""%!'+$("#"#""')))*(#&)&$)&#!&++)#*("%'!&')+&%#+"(!#'&$)%")$+)&$)&*!")&##'!&+(!'")%#*)$+%##)+)$(
@r5802
NTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGC
+
!3@@*G.HA#B-'*#G%9/(&*,:%:40?0&C/-@0"'?8**:<="+BE$<4H*%D6FA0$4H,/FG?.&0FG7=#()'B=96@.+-0:9+7#9>H'F:G.G.G
@r5803
AGGATACGGATAACGGCTACTCCGTGTTTGNGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCNGCTTTCCCGGAATTACNCCCAGATGAG
+
0&)GC-FEB:B?2EGG".#*7>.#)E,?8=4D$1+A3EE+:*!*$.@<:%?3.<'-+9B%<0(G%;C>G?5C3,-59**13D=-E<9;B;@8!A;%6:C"F,/"4!GE0
@r5804
ACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTG
+
18>*3,$5CD:B;G-:E/4%7#H/!+!A22;E!G('9/17@4**-63!F.C'=1"%.3B9:2"8"*!;$,;$*C/:%*;#:%(7EE*C!(C#8266/5+6B>;D61
@r5805
GCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGANGGTTTCCTTTGGTGCTACTGNTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTNTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCC
+
&*$-*,?72%.3-*401"#,+5>..C*GH>-(%(;FEDE=0F<%<$35A90$C=3E;'H<<@8BC7/%8",<?G>.G)')+E@-"8*7H'F';9;F'?*;H1.C3:#6-5&#'&*C&=4F&(5<?9D8G)E&G*?92E.<DA608!,.C!3&;0(B90&25-5$24%:+%3#E/D(HF./B#0)+#;@@1.;''51'#>0#:%7"F7@=-A)>0CD>C71!/80.1$:$F86%F3>*3;5!#+E
@r5806
ACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGCAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATA
+
.G0=9:EF>#@G4')<%8/!9#46F."@%()5G=)&51'=G*$E;A,7=A&1!A$>8AF>&$C!<"0.)5'15",;,!-1%.$,2.H7>%)C&,+8)B95(8%75=#:
@r5807
CAATTGTTATCAGCTATGCNCCGACCAGATCACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATT
+
72>9*E<;%6=0#?"-B)4BHBG'82B'4A>/,A*2)7#?#225<270<$-)#)H@&<H6%51;B?.-;%G*1H!0=24G?;BG$/F7E>-?,2(--6H+2/293&%02%A>@%@$E"@!
@r5808
ATCAGANATNTAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTNAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAAGATCTGGA
+
#(&%(%$(*!&+*$(*)()'&!+%)+(**$!$()!+%"%(+!&%"$!$(*"&($)!(%&%##'&+&&+)))#+*'$(#%"*(*)''+#$#!*!'%*"&##+$&(**$($(+&+!%%%!#$"'!"&"!"$++%"'+!$(+!+!+")&'$*!#'&%''('#)$&!('$%*
@r5809
GCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGT
+
6+#!3+?79:.81/@.G0(F>&E%(@'H<%8)GG8,G)"*C2+!8$#()F
@r5810
NNTCNAANAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACNGCTGCACGGAGTTCATTATGTTTCAGCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCNTTCGGCAGACGTTCACGCCGTATCCGCT
+
'#'*%)'"+)#%+*)+*&()'*+'!(&#*!+$"#'+$(!"#'&')'(!%$&&'(*!("(')&#('*!$)!(%+('*)##)"%%!$+%($&(!!#####'+#!'$$*!+$'#%!!)&)!*#*%%"%"*#$)*#'&)*&#(#'&(&!)"+'(!*
@r5811
TTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTNCATCATACCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGATAG
+
G%%.#$A'A</4CC050;.:6:%,.4@1+CFD$F.29BH17=(F"/2&G@321&+"*2:C&3;B"/+C.!$0+G0HG23'+F24E$/+$B:,&<A010.C04%*B?)6@<1@-*1&+6%AEA3-*>G+!0
@r5812
TAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAAGATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATA
+
A+2=,396C*@B(-2DC8<?7$DH6#0.=6BA=',;(E',3087H$/:0F68%&!.7#,>1#9:47.9#(-)/:8C#A+#7*.+?H-#@=!11/()%>BD181&
@r5813
TGTTCCTTCAGGCGCTGTTNCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCC
+
:E51"!1$+9%!#G#C'F/$!=68'G00'?*#:GGG.7CGB5+<F8.=F70@'!$5&8"+?<*;<3++6'$;8&">#39<#17EHA$/C"#A-!
@r5814
TAGCTGATGCTAAAGCTGAAAATNATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGANGCCACCACCGCCNCCGGCGTGGATAATGCAG
+
,(?0:H"(F+5"8?,B)%>>3858/%$#G!%F4$0!=E%8)&:),-7'3#0:;;='#@3!-8=<4C'E/#/3G93<1).*)D:C%FC9??'8EC/63?>F$:;.)6C5.+#2?-.;)#471A0*$D"&%
@r5815
GAAGATACGNAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACANCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACCATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGAC
+
@(A>#*3E($7D-%B='/883?"30/)"D&8A%7>4($'FG6>2.B4-,?$@4,H::H/$C;8:+#<5)-E>4F-:<#E6?1/$01<75@=0:"FF<&86B/G.4(-1;4"#;!95:EF)?4+@58BD!)#-2,1HE"($<6&62C%4D@7+$+&>D2/(D3%DBE1B$:A2G1HB-%9G!-70/&9'F?<7$,3)"#@?%.-72)/5CGG'5.0?*?&)F/&>9B,9*E:E?!>5.;8((+'39%B>0)."&#6C#%HB)>(-0C
@r5816
CTTTCTCGACAACTCTCCCCCACTGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATNTCTGCATCTTGCC
+
:/H6?D835D<.<-'@!,B6'936%8+9$E(./8H?EG+-@1'BD#4)%C+FH53HA*$,)>/3+#D*?.>E:"*6/90F<5;
@r5817
GCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATT
+
++&&%*!)'+*#*$&'&(*$%+#')&+%(%$%&(+"""++#&*&$"$"(&$*'$"+&($$$$%'*)#%&&'#)%*!%*#'"&%$"$#$#!#$+)%)#$#&%%$"('"**)(#"&$+%$$+**%+)"(!"*&%'&*'"''
@r5818
AGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGT
+
%CD+$@BC,+??);+,17G@6.-F$'3B">DE2=B!667/#C9HG&$H38+D4$0AG.0'H6#0>/CF2DE;&1.5)4E)63EC?;?6)$2<-/7,A,3G&D,B//#'CB)1-&*5;./F@$*&(;,(+GB',/$G%*+D1(>H,98F!&H1%/.94
@r5819
CAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGNCGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCGACAGAGGCTGCG
+
B">6+-H-9.68A/'>2D.!"36E8B)*7D8+2>*%$)H4:!8::'6%>C;9-9:)A#<;G,""$@H/((;4/-'EA1+-#3AB5=EAC6?-//.F)F$1<B/>,)EB.8:H6/=$EE838D@C=E!0A??
@r5820
ATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGCTTATGTCGGTCATACTTCGTCGCTGTCTCGCCACACGTCCTCC
+
D=!75!GF(#3"195;C%-$F3F+AE#6F0BC+-84;5(1#/3G"+EDB<7"#F#;.8=A(%),!,?<90*3!&$#.>'(!3((0+273'D>E8"C01?)$B&4&3*HH11,
@r5821
NGTANNTGGATGTCGAGCAAAGCAAAACAGGCGTACAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATTTCAATGAAGGAAACACTTGATAAATGCAAAGAGAATCTTGGCGGAGNAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATAAAGGTATTTTATGCNCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTNCTCNGGCATAAGTCGGCCACCATGGCATCACAGTATCGTGATGACA
+
#')&""+'&!%#"')&#(*''+)*)+%"!#*#''$%!!$!$&(!()'+!+'#!$(!$("!)!#)($#'$$$!""')+))#)%&%*!$+$+#***&$#!"#$%)"+*&"$#))%((#)#*"!))"+!$%"*#($+$")$$(!#$"$))'()!*#)+'')#'&$"$$&*"'(#*!##)(!$%&%!"+)!#&!"!)++%'!!'&)$&**(&*)"(#'"(%"!&%#("(&+$"+""$%'!+++!$!)$"+$)*('"%"!#)#(+#)&%($%&&)!)"$)!+*#*&$&"&("!+&"(#+'"+$$"!"$**('')%"#(#))!*("%('+!$#*"!$))!#)'+*(&)$%)(#%+(*$&#$+(
@r5822
NCATCTACGNGNGATTGCTACTNAGTCCGGCGAAGTCGAGAAGGGCACGANTGAACCAGGCGATAATGNCGCNCATCGTTGCGTCGATTACTGTTTTTGTAAACGCANCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTC
+
!!""#*%&*$%%(+"%"+"&($++&)&&()'%("''$"("+#!!$*(&+$")&+)%$+'*'%%+'*#&+'(*$)#)*#&!$('''&$%#*$+#+*$+$#)&%'!(!((*)")$("#%%!%('"$$'$&#&%'!#")%)!%*)('+%!&'$'*'*''!$)+#$*!"!#%%"'$
@r5823
ATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGC
+
4,+1?+,<;9'F6ED#*?A#%171.-#50".F9.7,<?,2##&BC@(!D6-
@r5824
GAGTGCCCGGATGGCTTCNGCCCACGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTAAATCCCCGTAAAGGCAGATGCGNGCCATGCCCGGTGACGCCAGAGG
+
,:!9/.(CF-;:@F("=A'/,FGH)(*8)8#?7*F;"<--=$*%45!=',,7.(*;/&(;A.&$59?-;D-#F+%60&,#)0$%)!BD6F0FA(3?C1?,1A1@82/*4(D
@r5825
CAGTCCTGTNGAAGAGTANNNCATNNAGCGTCNCCGCTTGTGAATCTTCATACACGGTGATGNTCCCGGCGTGCG
+
$*&('$%*!"$!$'(&(%#%!)&*""***)%)$*))#+$'#+!("*+)&!")$*$#()#()#$)(+)"+"*"!)%
@r5826
TATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCG
+
1">":!8G??4.B!9$,G+F'2.D2'A"2-%;+1*H26B;5#
@r5827
CGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGNGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTC
+
2HF0.H8<46*1!DCE<6-/9D5;HF;$1,7<+.1$1HB7#G"CF1*?HA>2$C/*'"<<B%H1>32$AD?((@><)D=B"4+>$/4
@r5828
AAGACATCACCACAAAAGAAATTGCGGCNATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAANCAGATCAACACTGAGCGATGCATTCC
+
DD:"?;;%.A3.-,?>&6:;328=FBH;F'?$"%$A6-.C(!B)%+CGF;708,5:;=@=!%)=;F6.&DH('196,CAD(A5H%H3;2.+>?$"?E5&/@A.37
@r5829
GTCAGAAACGAATGCTGCAGCGTCACAACAATCAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGACAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATNA
+
(D.H):1<F@1+;+31D<GC>#0*%!=!':'889(A?G,)"E&/2*)23""C50&%C$=C(#?"?,)>70>>>)F6)5+=13=AF.16F'/1'@%)HA">?0!"=C.7&2$C99*A;C-1+>8-22<
@r5830
ACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATG
+
(?*B)0G5;7195)88)(*7.'BG%+E1*:&*/DE"9?:**55
@r5831
AGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGGCAGTTCTTCNTTCGT
+
0+%C&+B0/B76!1<3GEG:.!&;-+0G@2?E%93/('B+(=>?='B;B?%/H/.4>4A?&4#*#;
@r5832
ATTCACCGCACNGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCAGAACAAGAGCCGGTNTCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCAGCGACATTCTTCCTCGGTACATAATCTCCTTAGGCGTTTCCCGATGTCCGTCACGC
+
9>2=ABD.#-*;#/%6F&91BC7#75E)8/6);#-BE<*14$DG$<#C>!6H6=.B6/6>B<F<?/@=,)7'.A=;,9'B=55?(BEF4%<6;7?"/4,5)B!D!E/7,B;(=F)3#C%-93G7.$9:)AF<(B8;@9-E4EC8>4(@G69!7+&>!-?88(',0@2/67'H4#0E4:596?/,0AG=E8G9*:0.!F1>"$C4<$9+9>52BG-1*5(=+&=C&/'&/"''('A
@r5833
GCCCNGNCGGGGANNNTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGNGCGTACACGGATTGCATTATGCCAACGCCCCGGTGCTGA
+
&($'#(!&$&'*)##"*+(')*$*%)!%*+&#%+'("#$+)+)"%&&"&**!'")$((%$)"%"!$"#%&$$'**#($(+*!$()"'#!*!!+#+&)("#*#)&*+
@r5834
NTTNNCTGNCCNNNTNCNNGNATCNCNANNCACTCACTAGANAACNNNCNCNNTGNCCGNNGCGANANTTANNNNAACAGCNGNGTNCAGNNNNATGNNNANGAAGCANNGCNNNNNNT
+
!"#"####"!$"!#!!"$#$!$""!!"#"!!!!""""#!$#!#$#!$#"!"!""$#$!#""!$$""#""!$!!!#!$$##!!!$$""$""$"!"#"!#!!"!##$#"#"$!!#$"!""!
@r5835
TTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAA
+
2%,/!=A092A8DD20*>7;3#/$%FA?@<.@B1<;F12A?3+HH"
@r5836
TTTCCTTAGGNGAAAGCATTGACTACTATGTTAATCTCAGCAAA
+
@*@+BG86,:5%0*4-!2F.0;7++=%A(H&==<60<1'>%F3G
@r5837
TTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACCCACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCT
+
1/()B'53D*-316=')/:'F8?77D3$E%&&!A75'<)B=%4C:(E$@"4B!/19@,F4.E?AF.EA.+-="=%75(%#1,+!H/'??
@r5838
TCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGNGTGGATCCATTTCTATACTCATCAA
+
CGHD#20::DD"0G2=B03"@)=&EC<F.H$!)F!:"?'5E*73*$E1EA:2E?G@).+!+5/+B=38>
@r5839
NCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTCGCTTAAA
+
:G*211*#$'#&E7B0(,.A>+8D'4A)7#='G@-::''';"44>B,+->:(
@r5840
ANCAAAGNNAGCCAGACAGCAGTTTCCGGATAAAAACGTNGATGACA
+
%&%*(('$#(""+&&&+&&&+&$$"&"('%("#%)(#(##*!%'&''
@r5841
TATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATAGTAACGGCATGATA
+
/8E>$0C&:F4#;F>3>4%#<D1H$)%+A:2+0F@4HC,0&529"7501%3'$,)H+#7FD5%A6C<*-.01;E/C,C73<<B'1'D-",<D/C.<+/>73D7C1*4H(8*>=>3E-
@r5842
CACTGGACAGTCCGGCACTGACCGGAACGCCAACAGNACCA
+
B3%<6+:)0ED''7+6(,C<;,#%=@'*>.DC?56=A2/6$
@r5843
TCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTTCTCTTGAT
+
AH?.$2:'@/D'E>$')=F>/+EF,B&9#=H@@F#D$9+.+#.6-:.>%FF,
@r5844
ACAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGGTGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAANATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTNCTCGTAGGTCCTCAGTCCGGCTTCTATCAGCATCACCGCTTCCTGAACTTCTTTCAGACCATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGA
+
%CG7#($&&'=%.CH#A6;?,G4%4*)!H343?/3,5D6E1*/#G;>B+$)'*-?>G'EEGHC5G6>$/5*'%D60E18-AEH.<'4;8EBH136EFG+62--;!E:=+H,!4(,=5*2.2,*'?4@?953;%1:()4=3EE>&,)E$("5.$$$/8(?'C*:;A(CD0.=B/7%3"@&8/&<.6GDF9!H%"(9%'E&@+8A8"G&$.!&8<>@A/>;8:,(:=66A)"(G;4E/E#:192'3;+@1C%)>C;?,:7/+16$HE4'"@7DF!/:"6%+E;D;/-)-D.D9>.E,C9337C,406A7(3:("!=25<-@:2:=H4300@/':"
@r5845
GCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGN
+
%5D(&-2!=(&CB"!@/<#2C/D8'-1E*?:6?G,D#2D'0""
@r5846
NATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTT
+
!H&+#C#F%((%3(E4.@8%-#"<<G32.1%")++%.1$>>
@r5847
CCTNGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAA
+
D*348.&<5/"#7%FF4*D&=-8><"<>D<*!-6238(475
@r5848
AATAGCGATGNGTAATGATGTCGATAGTTACTAACNGGTCTTGTTCGATTAACTGCCGCAGAAAC
+
%5#>G5%1*-B&,)$#=(-)F>'0D'2*8)>G@DD&4&B6'4GFE&-#*?5-H/8!<:!A*)-;+
@r5849
GTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGTTAC
+
-87AE9-!5GA"E,;F?H7"77$@,54/,$!3)D*AD@G,>5H'F(></>/B-<"A(9
@r5850
TGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCAT
+
>':=-AC1E$,#/&G;?"+-=#A$A<:BE@F*+"3"4+3#"9G13===+'CD0&'G$!$-E:'!=-"$:3<=5.
@r5851
TTTCCTGAAAGGGGATATTATCAAAACCATGAACAAANCCGCGCTGG
+
8*;53-/9&>H"%D@.+54)<85A=%"G1C)H9DB5"/<D%'"9:((
@r5852
GAGCGCGGCCTGGCCAGAATGCAATAACGGGAGGCGCTGTGGC
+
.E'*53/50E>G-3%A6&'@/%/5B-.*%8B!,&@9."5&@)F
@r5853
GAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTGTGGCCGCAGCACCACAGAGTGCAGAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCAGGGGGNACCGGCACCGCTGGCTGCAGGTAACC
+
=/:F@@,=75B7EA3C8+$F90"93+=H18&D-)=26A*5-'4H6:E798$=F.CE)/:CCG)HGA.9<+673$1D0(.09?B=(2*)53,65.BGD$+0=50%//4DH:%=@='3%(!;BG):>38G@&E&C?&EA.&F?)&$8&+($7;4#2
@r5854
NACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTACCCTTNAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTGGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGNTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGC
+
+#!$&''!!$(&%%)$#"'$$'!))$%"+&)+!#&()')##*$+'+(%'$"*'$%$'%"($!%+!*&#*$$"&()')%+##%+!%*#"#!(#*"*+'#*%*(%*'$+$&%*"'!!&+')("!+$"!*$)(!%*$(!*#+)#''"$%!%$!)!)!&++$(!$+$'!#"$*')'$$&*'&"%&$#)$*+)#*##+"&%*+*")#(!($""*$)'"+#$'!&(((!+()'&))$&&**&!(*+"&#!%''*(*!)$
@r5855
CCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTG
+
F1C0E'/9?6?C-%,84<!,B"/1?D(.90&E747/4@AF>.+-.%AE,848?F5,D@2>,F'+25"E6??.2>
@r5856
GNNNCCTGGAAGAGTTTCTGCGGCAGTTAATCGAAAAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCNATTACGGGGTTGGAGGTCAATGGGTTCAGGATGNAGGTGAGTATCTGCATATGA
+
%"#!:4)@.CE1A.)6:95</D2'6=6&F-"%,H84'42/"277H0?+48D=0AG6=""$9?*H3!=/8;?-&;*,?B/;4-#%)<(&>?/E12)G481-9/<!87&.?D1;.3H7HF5D=5+'<>57&
@r5857
ATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCTATGCGCGGGTTTTCTTTTGTGCGCTAGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGCGGTGTCCGGCNACAGCCTGACTGC
+
5'D32,:!2'/?C!"A,869G(!::@:+"$GDB<2,@>E%*9(3;?<B!;&28=38%+CE?H!H.=*8"A'1''"@A"+(@B,3A%G7"H%>!9)&;/%@H5=B&->4@45!/:6C/%*$@*43$8B=98"
@r5858
GTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATC
+
>.)((*98/>%6*(7E2H5-!6*EC;GG1G;.8($E+H>3@9C2*76"A90*'&@#):B:+>A-&72$.B#<-/'5&6F/6-$A?3A3)3<<9+<C<G9')&H
@r5859
CGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCTGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGNTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCG
+
..&+7#("%*0+D/CE.!.%"E32CH2>'8*.*D$F(-@<<)&EE6/8/++E:%.H,/F'!3120,3>!?#==;H)G)$%6H:/CB813@,7%)";//B.2+6656287&@38+$02))@E2'&H-B.;4-H#1:-"6E/;E(;);.B<?"@$':))94'%7*A,($7!9/</-0?1HB=()!"-;(!3FF?$+)<#7FF?=HE8*'5$(+
@r5860
CAGACCGCCGTTGAATGGGCGGATGCTAATTACNATCTCNCGAAAGAATCCGCATACCAGGAAGG
+
$=6&!A:EG=6..+4C8D7D1$)-4>H)$6D$B1>8E.!C8$-3#9394&A'&,66-&.HE%/2C
@r5861
ANGGGGNTGATAGAGGNNGNANATTGCTCGCCNNCGTCAACGACG
+
'#$!$%%)$'#*%!$#""&$&##"%'"%#$)%""#'+(#)#))((
@r5862
CCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGT
+
&EE=?-4A3-@6@=<95"83-1.$D(C?=>07&96C0"6:2*94&.5$:62":'$B@BB937F89%72$@.?F!G>%$9)(;7B6#+;(H&H0:*1H!?9GGH05A&
@r5863
TCCGGCAGGAAACACTGAATNAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGANATCGACCTG
+
'?=2<;71H+#9A32@5,%&*')';C&)F0<==76A>%6&&<,=3%B'2&%:F$,6%6.&9?C*B@B=2!#B+?
@r5864
GAAAGAGACGACCACNGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATT
+
-A?60&9+HH>#1(8F$/4-3(%'8"5D,;-16$)!4;.=8HE-9;DD!:2?'<<7'+F?/8</C%C<!8>E85:<
@r5865
TGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACNGGCTGCGGCATTTTGTCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGGAGCCACAGACCGCCGTT
+
GA)BAH140A35GH)&=@1A':E-D)364"<7?HE;32G.DB$"0;'9@@99D-0&B%BC+FG6A-G4$.D&=A)H0!%-/)F#;<ED21CH7@:A3C<)BG@)FG'%G2E$2/$6-46/',#8;E7A%DG01%EB4F0?9D>&AD<!-GF!)*%9B>!1H5&H!A;5&@
@r5866
CCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGTGCTGGAGCCTTCAACGCGCACGCCCTGTCCGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAAT
+
3$6A.&",DH$:+'=B/"1;@F"8,,$>*B15%%78C@G#<A/H8E,2("26#/&@8FAGC'G%91$@)H.A@=1057&3#+.?,2C7).*)A+6-<B,&6#4?5,F2'3"5%?EC45)#C$,E716&8'5.37D:.7&55%(#/2-"(1<@94>5$/"H()90->,
@r5867
TTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGG
+
7';)!GD0/=G;6/7)A3+!/<8"67BB4("1%?."$ED</B?8;+C:5F*7G@2
@r5868
TTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTATTATTATCATTCATTATGTATTAAAA
+
>D+>&GD40H+:6/><D3C>'9%)54>)0/"F%=2!,<+G0GH.=:+7+?09-*&2G&(/.,G6+<5!D(;E,/G7E4F$=6,F#21-F
@r5869
NTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGCGCCGCCAGCACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCANCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCA
+
".B21B;&,G'GE),):1HH5.-;)%B#98+/,<,#<!51&=BF$2"-!.G928,8**-A'>(G1$#3GH2:!F"H6G'FC!$2C*B"-4%@:7.0+=+*@G(9#9DGFEE5@DA%*5/&E;1*.%&"2%*!:ABAA'B36.2%E,="D!9A.9-&-9A&3<4<;D=*1*=?4<H6>H7FD<-C/.E!3C,?5<>>!2A:C5+/$E?@"270&&8@G&#7E'-A.336.@-(0)F'-/$&A-,@2(>$7%E1E8A3>"6C$@?
@r5870
NNCCNCACANATTACNNGCNGNNNCTANNATGANNANTTCGTNGCCTNTANACNGNCNCGCTANANNNTTGNCCTCATCGTTCCTNTTTNCANACAGNANCNNGNN
+
#$$#"#$"!$#$$!"$$###"###"$""!"!#"""""#$$$!!#$!#$"###$$#!"!!$!"##!#!!"!!$#$$"#!"$$$#"!"#"!$"#$###$!#$$"$##!
@r5871
TGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAACAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACNATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACAT
+
7&*C(#:(4EE?$7%8=#D>1$5F;E$F@57E&F'41?<#78G/+%70.$:4E&>3F42E@/700);)",@)(%);5;&+:3.9$**"-.H%<$G6,A5/.=-?-":'18-.2@CH)3C%,$;D!":32-@,;*DA>7A*+2>%:3%*3"'=G%A@%E'?F&:4A!5D*B>G?&
@r5872
CTTGCAGGCCAGCTTGGGATCAGAAGCCTGACGNATGCGGTGTCCGGCGACAGCCTGACTGCCCAGGAGGCNCTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCNGG
+
?B=C6,F:(E<,E2"%7<<;5&F<1%2'9A+4#*/E9<0+E6*;<%E.D:D3/B"EE"2A<$BE-*0H?735E8"7=(C*GH'01+"5?,2;EE9*!;7()?)?D&5-$E!51+F<=!D09B4%0$3/'4!%$
@r5873
TTCATTAAACCACGCCAGCAGCTCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCC
+
>*?-!8H*4D=488(<A;B5G,.7D(+37&#GC@E-!65)D#,</)>H)":(:6(1%D3@FA&/'?/1ED>=?#@%2HG'-!$F9*:1!(=(0&!.
@r5874
CGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGAC
+
F9.94'CG72;9@04;G&%'$3-8:F(".D6H*9A>BH0=(+C@;+"E$H+8;%E"H
@r5875
CNGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGG
+
BECC:3$":4C':9(.:?)/,;0F02$"-)5FH5!4E7!#4C$##F"",->.CB+B&)7F@(F1E-#"G*%
@r5876
GCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCANTCACCGCACCGATAACATC
+
'F">DC!9F=4*D<=5=16@4*8G97-="-<8)61@0;+&=E@/68!B4$G,-'+G3.1(-EH-6B/732;BHE5!,G'904:*8C2C$61+6(1/47=7$1!9>*!/3E&4)D7$<&0*29!F@7+,1
@r5877
AANTNTGTCTTCTTGCGCTAATTTTNTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAAC
+
%")&!#+)'&(&&))*()%"%*%"+&*"%!&$!+&$"&%&'+$)&"+*%"&*'"(%+"#!*%(+"$!+!%'*$"!"%(+)+("($'"#"$$$*$$#$$&)$"'(#%''&'))((('*'&%$%#))!$!$!*(''$*+*+!"%'
@r5878
GNCACGTNGNATNNGGANGNNAAACNCGCTNCACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTG
+
"!(*''!('**%#&")*$)"!()!*"(%(!#$+++!)(++'))#&&&##$#!"!('+'%($*(&)(%!###+*$)+#$+)$(('&++%%+'&)!#+(
@r5879
GGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTTCGTAAACACCACGCTCGGTGAGACGTGGGAGGCGAAAATTGGCGAACGCCCGTG
+
E&&;1<D03#*9H*54+@%8C?E-#%ED0(!G4CB75,=%/G!55A7:>*?3>H/!("37"A*2(D8<0<D<@+E)B6HH%-A+.D=>.".:!$
@r5880
NAAGCACGAACTCAGCTAGAACGACAAACAAAAGGCTATCAACTATCTGACGCAATTTGCACNCAAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGG
+
$+$!#&!+"*)&*"$"("*)&(&%'#'&*'$""+!"!$!!(*$(")#$*+%&($&$+''$)"#"!())++'("&$"!(#(+)++'!$%#&($!#!)"!!"!'("(
@r5881
NGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGTTCTCCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCNGG
+
'F90,A80=7A$3.5"A%GB;,0:5GD98%.CBBH?"#1)=-H?GF-(5D"2!9)DBAC=48","3F2H0;62DA3@=B=,.!:F83>'@*1#<3:?3B5-6-#<1%4%(-18B:(229.!:E0F%3?:2-'+(H86@%':;D)D=G(B4H&EH9;18)>50CG#A"HA.21)13:A2>@9>D#&:DCH1;"+3&'B)H&?06"8*@HD60!0G3"4!
@r5882
GCATCTTCATCTGCTCCATNACGCTGTAAAACACATTTGCACC
+
<6/>72-$&!B;!6*@8:+?B.G1C11C;(%7!(D*4C($"<?
@r5883
CATATAATATTGAGATAANGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCNCTTAATTTTCTGGCGTCCACTGC
+
H?,#.G;5(<7/$:F2;&=C>E,BHG(.2!EEH45-@:B(965G44=$")9ECH;#&52+-",A:)D9706%,<.>A/F#!>,!8F:;
@r5884
NCATNCCATTGCCCGTGACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATT
+
#%)&"+('+#!)%"&&(''((#%#"(+!)#*"+"!+'+#%#)+&**&+&*"$%!"%"*!$&)(!'!!!++(+++("$)!'+#("(($!'"""%&")#
@r5885
ATTTTTTCGTAATAGCGCATCTCTNTCACTCCATCCGCGATGAACCATGAAAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGA
+
G=>29'.GACD3"+G>%@E38)B>=B.&#0?G,,0*3/5&0.=:9C/F83>9=*/B@>%CE?"B2'@1G6=*3AB/'GD"B<@C"10@#G"3G)D@;195E:",:#<+B'%@;E-%)7%9-,7*D'01!-CH$H?-;?E>FD@F)8>2;$D
@r5886
ATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGANCCGGCACATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCT
+
28A@53.6=/H!D-,GG85'HFH7:FB;1(H)?G.(@>!?7'1@><(>7?6?$9H26@.0D92&@/>;0*(@)7/*;HH,))>C?'=9H#6G+8(E*8)5AA0%;771#7;A"
@r5887
TCAATCCATNTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATGAAGATNCTTGCTCAATTGTTATCAGCTATGCGCCGACCAGAACNCCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCG
+
-H(0"F)BF@A-3,8$"',,6-93:H42*!0/996?+=8/2F(4D<5%G@F9#D7)0!4,2B0F">49$#3<5"1'C/E6CE@,,7%$+'?57C0&&:6+$?8,G<!-3<0CHA03F+!,7EE'526A(?=E590?93?>#6E;7'&>@4:42E"+<.=<?BEH:B:4H7$$37%'?66)*'DG<A<BAB,5%A(=025?22ADG.:=+)@(##,C.:(2/,0%%BB
@r5888
TGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCNGNCAAAANATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGCCCTTTCCGGCAGGTGCGCCGATCNCCTGGCCATCAGATATCGTTCCGGCTGGCTANGTCCTGATGCAGGGGCAGGCGTTTGACAAACCAGCCTACCCAAAACTTGCTGTCGC
+
D,8$G$16&8125>+:20>(<9.'1$,4>(&5-F3@C:83#:98.>')'1199'=@."@B-=@4:3'?6-7";$H(;//'7*75G521,($B$'#29B7H2B2>E*G(C;.3:&.:H(4?!9"/3)5/+-@38(5(C:4:1@1)1%@0;4GB981E6"$(9A$%52;(0-F,0E:D7G">))>92D$)B?0$!:+3/.>F6A>C;>3>0F@10B8-B$";$<-0'
@r5889
TCCNNCCCGTGCGGAAGGTGGACATGGGACGTTTACGNTGGGCTATTTTC
+
(')"%%%&+"!&#(!+!$!+%)!+('!#)(!(!(*%)')+$&)$'*)%&)
@r5890
AGCGTTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATA
+
'8*=1HF8)8;2-;45H2DG'C$,<()E!D%1>H#,?0:(@+*"3*6C1
@r5891
CCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCGTCGCCCAAGCTGG
+
.G%<,=C>8*!<$%/HEGC*5@CC@>".E=-:>6E-:9##E:5+'BF&-@+39G&5+:D"F
@r5892
TCNCTTNGNNTGANCACTTAACGCCACGCTCTGTACCGAATGCCTGTATANGCTCTAATAGCTCCGCAAATTCGCCTACACGCATNCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGAC
+
($!%$'""$"**#*+)*('(#)'$+*!"($#(&++#(+!((*!*#$*'&'&()"%+#$%'"+)(&%**!!)*)*+(%$+$%+#&"'('")*&)'!#$")$)+!)!&!'$)+$+(+"("*%)(#'$*'%#%!(+"$"!#)%$#%!%+""''$+*)&*$&%%#'$'()')*&!#"+#((("%(&')##+'%$)*'&*+)%!"')$$$("*)!##&+*&!*$"(+
@r5893
AAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGC
+
73$8B7&;264E933=(EB'E%/<BE>'=@5$(%D1BH499DD"9'6@@C*:H#;F5,3*59<5,,77!)7?"@CG'61'25&'.7+0%)/A.8#7"=$@2"0C$DF)D*F?3C680'%9:+?H(87?;!A-DD9?G">*H)6B/F%-DF?<C0.(&43$10E%*G'4+'5B=$A3&6/@,3*:C'6;/<2=8#+,H42;=;'0"9-HB%.+.,$-AD-H1-CB>$#"!1,9"4$&=G9"@H(>-+!:66'F1*
@r5894
CAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAANCGCG
+
@9:&,%'!1;$03$4A)!7%8+CH*A3E%"&%C#4#8B@1.*'F
@r5895
CTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGNAACCATGAGCAAATGATGATTGAT
+
.(#)=B2"0?9HF!5*56@3)!'F>F/E>>C(E$FD1D5'(!=!&.(HCC9CH=>=E=:",>867-
@r5896
CATGACGTNNGNTGACGTNANGCTGATGACANTATCAGANGGGATTGCAGGNGGAGTCCGGNATGGCTGAACCGGTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGG
+
)*(&)'*""!))(*&)&(%$%&+##%$#%%)()!#"*&))#*$(#"'%+"+&$!(&)+$+(%()"!('(&($(!(###(&)(#$*")&'$"!#!$'*&(+%()"++"+%(#
@r5897
NTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCG
+
!G2=,!H)<"+F%4+(#.E%!6:1A9))"11&=6=6?+?)2:<D(=&.-';H-7H**&:H!=*H;>6'F=&2
@r5898
GCTGAAAGCCANACGNAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGA
+
7@F8:;"=580+/,3A9;=C,'DCF)CH41>*<B;7*(!'$%(7@6?-GB9,"7
@r5899
CGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCTGGGACGGAACGTTT
+
%=H.<A!1->4;.,';550)#B%!,1&"8>;4:8!2=0;G#37&:AHBBG3,<18&+3'@-"/&A$"@G+@"<0D:@:4(-/GG0)&>>A/GE
@r5900
NTGGAACAGCCCATGTTTTTTCGAGCGTTCATTCACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGA
+
*&$+##'%*")%**")$!""$*$%($#*+&"$)!+$+#&'&'&&$)'#%'%()"'!)"($"(%"**+&)(!
@r5901
CAGCGATGCCAGAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGAGTAT
+
C.02.&=-'A9%>;4%/8:C:.2;B%>&%.A@0=06E>F!+D#G$7'H=8,:::..E-4-
@r5902
GCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGC
+
/2<'AG/+24A>2.>/%/"D8=-H%:)<28G%.A:"C&,*E=:
@r5903
CAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTT
+
)+$)')%$&**($"$&*!'##$!$*$%"&!'+%&''&)"+!+$)&$
@r5904
TNGNTTGGAATGCCCGCNCANACCNGTCTNCTCAGGTCTCCGGCGTGCCCATGTTCTCTT
+
*")$"*#$$#$%))**"$($'$"'%')&#&(!+)(''+&("!!('"'+'&+&('()#'+"
@r5905
TACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCC
+
,/8HAG51*16A.42=)8&82.<%0#:=@%71-C?(E!'/%;6D
@r5906
CCACTCGTTATTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAA
+
DC);3'E?>'#23H1$H!2%.BD$,8-!?'=,-02B3@"9&*0C)#0(1)5&*2F!%;/34=+?*C!00'7,:?8!3AB38-';7G>44#(31'7;)ED.27)80;D3)5C/3@B$G4/&>7':/9=
@r5907
ATAGGCGTTANCNGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCNCNTCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCCTCCGGCATGGATAATGCANCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCANCCTCAGAGAGAG
+
!"')(&(&%($)&()+)!(+"%*%*$+)*)$!(#"**"+!$)+"''"&*++#"!"#'&$"&(**%%))#+$&&"'$'(!&%$&$**!%$!!*"))!&$"+&$#%%%""(('#!#'#(+('+*)'("&'$$#$'*&%!$!#+&%'+$&%)+"%'&$*+$$'#**%(%$#$''()'&+((+&&+"'*$##&#'+($")
@r5908
TCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCAGATTGTCAAAGACTGGATGAAAACGA
+
0$=D5)D(2@HC&:0+E1C/;0A<$/=.%-AC-(&2?)GD*!+(?$'F.&@,AD1B)/79EF4
@r5909
CTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTAACAGAAACCATATAGTAAATTAGTTACACAGGAAATTTTTAATATTA
+
:7>.%1:&+1,+F.@0H3C8*,F135#,EFB57+&%#3:'-89*CB+5H/))"27!,7&@.9B*+&F>1,B40/8<A>;2004'H:-DG21;8=:%.)+
@r5910
AGCATTTTCACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCT
+
CF<A3?E1-1B"HCD'=#?-0<=<E)0E;4B$->F:F"'<@0:7=?)6!3?B?>)="@8B;!=1*?D)?9=E"?!!=1-@&,<?%:%;H7.B:5BD()F
@r5911
GCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGANAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGNAACGTCGTCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACA
+
0@3@+$'G'-'D<=%E?16;D:.7D4"E?:/;.;F:G.=./$<E;B**8@;/!3"1D'E+,2D1;"</>DH,$8!**F68!E:HA.!-%*F9<14?,?D!69.?+E-(D?%/?C.>>F>3'E;3:FB$14+$H28###',98%B37*C+=H<9;'=;,*'!6?".(G.FA7AB%#<$&(9C7'<A
@r5912
CTTNAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCT
+
#($!+'"!)"()$"$)$%$('#*&)"("$)&(*&*$"*)#$#$&"#%#&*&*#"+&%%'++'$+)'"'*&!*)))&"%%'$##(%")#+!!&"'$!
@r5913
GGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACANGTGAANTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGTCGCTTTCTTGTTCGTAACTTNGATTTTGGTCAATCACCNTGTTTTCCTCGCACGACGTCTTAGCNACCGGATATCCCACAGGT
+
,+(3F:@*0E?H/)'AF8<FD#$=B=-3'GED&#/':05)DD-!".!D&CF=@!CC&74D%-H::G9(#A).5;D6+)(/"5122:#$$$+C(,E%??C8+A=2?B6%7/&-B5-#:."G)@*8591$5@@C%3,EG7F,3%@#5:4>#'A884-7':9D4A?H8.@8+H167"7.4C&#
@r5914
ACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTCCAGCGACCTTGTCCACCTCCACGCCNGATGCAGAGGANAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAG
+
+("$+(!*))&!$(%&'#$"+'&$"+&!"+"%%))!$&"%#&%%&&+'*#*+"!$#%'#+!&'+"*'#$$(+'*!$$$'#(&)+%(&'#'*%"(**!*"&$')+&""&%!&((!*#"!"&&*&(!#++'#)$#%$%&+!*!)!(%%%)'&!&!&)*%++!'$*%&
@r5915
ANGNCNGNNTNGNCCANGNNANGCGNNCNTNNNTCGTTNCGTAGNNACCNANANTNTNCGTANCNTGNNTNNAGNCANNNAATTNTNACGNNNNNTANGNGNCNNTCTNNTAGNGTNANNNNANCTACNGCNANNNGCANNATNNTGNNANTNANGNNCNGTGANATTTNNNNNACCNGNCTCGNNATCNCTAANCNCACGGNNNCACGNGTCNNNACANATNGCTNNTTCNNTTATCCNNCNNTCNNTNCNCGNNGANTGNCNNCNNCAGCCANTNCNNTGAANNCANANNNNGTNNNGNTNAANNGNTTTNTCNNNNNANGNNCCNNAGGTAGCGCGNTNNT
+
!#"!##$!!"!$!$##"#!###"!"""#!!!"""!#$$!$!""!#""#""$$##$"!"!$$"!$"$$#$$#!!$$$$!!#"!!""$!"##!"!$"$"!!#"!"!"$"$"#""$""$"#"!$"$!!$!!!!""#$!$#"$"""$$""#!!$$#!!##$"$!$$$!$$$#!""##$$"$"$#$!!$#!$!$##$##!$"$!"$"!!#$$$!"!""!"!!!"!$!#!$$"$"!""!$#$!$""!"!!#$"#"""""#!"$"#"$$$$!$!#$!#$#"!#$#$##!$###!$!#!"#"$$!$##$"!#!#$##$!$!#$"!#"!$#$#!$"!""#!$"$$##$!#""!
@r5916
ATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCA
+
9EBF64%9F=1AB30>7.;@4E4279D%D*9.37>4/!H=.6@>687-00''3'82#42%BHEE*0*!)5
@r5917
NNGGGGCTTGTTTAATCCAGTAACTGCGGGGCNTTAAGGCGAGTTTTCGAATCTNAAGTT
+
("%")+%*'&'*$&"'($!*$+&+$)#$*"&$#*"#''*+(!%*#$$!(%)&!+*#"*$&
@r5918
CCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCG
+
$6.(('B6?C(":F%'>)5H)6!/&=.6"5-,75:G>F-'"H>
@r5919
GAGGCCACCCTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACG
+
%#8<6=+@5)(1=65;CE@$66(#CE,$)GC=D)39)&?%+&*@(EA*(5E.9-@G3>#A>
@r5920
ACNANCTTTANTCNACTNNGTNGCNNAGTGNNATCGNTGCCATGAGCGANGGGCNNATTGAAGGTCCGGTGGATNGCTTAAAAAGCGTGCTGCTGAAACAGTAC
+
(*!*"(%"))*$*!$(##%$$$#')!'*)##"))")'%(($*)"*%(&($)%%&'+%)#$)&"('&!!++#'!$')&#'$"#"*!#&+("%'"%+'))$$#!*!
@r5921
CTCACTACCACAACGAGCGAATTAACCCATCGTTGNGTCAAA
+
,E#6:).6963/B?=%4&>A/-<H'27G0+F:%$-7+=A3>D
@r5922
TTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGANATTTCTGCACCATTCCGGCGGGTATAGGTTTTATTGATGCCCTCATCCACACGCATCAGCGTCTGTTCATCGTCGTGGCGGCCCATAATAANCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCGGTCCA
+
B<(#69(>H.8%/;>9?5<A(3.%E6(B193#!!6FE>?,D6G6#/344*B0#)4*3E2BC2BF'!H4?7DE3C(..A0C">A3DG;/6E5*>%'F3D*3)'"?!4+,<=)9<CG";#&G)ED5=F*EA0,>5+6FE%6#G-?3$C5C0&BDFC&=5G=DAGD6GAGB=>1+C++2*)%E;8H6A=@4EB*A2+?%/C#5$)E8$<(+%&BB->H+F(
@r5923
AGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGAT
+
2"@2@,&::A+"<:8*#>69;=.,C+G4;-E""(<3F??-#5&/'
@r5924
ACAATTTCGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATATTTTTTNTCTGAAAATAATAGACTTATCGAGTCAANAATCCCAAAGGGATATTTTC
+
+'+#%((+(!)(+!!%&&#%($!&+&!&#'!%+))*#%)')#("!%)&+'%!"+!!!'%#%#(!!*+'!&&)*)+(+)#!&%(+#($&)&'#)$+%()#!$'!$!!!&)
@r5925
AGAGTCTTGCAGACAAACTGCGCAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATC
+
B)E5&*/G55E4>-<?-CD?6H!92%D>$3/F0(3?/$1%D#<@5<C1B@%)>$!837DD,<A@2#A15A51<%.$/,0%6A!%<3"@+2@&2&==2A;0B6#/B%7%+6?469-,
@r5926
CATCAGTAAGCGCATTGGCCCGCATGTTCTGATACAGGTTGGTAACCAGCCAGTAGTGCGCGTTTGA
+
?62.)(=8;;B"C+3A805D<BFH5%!CF3FE$?!>>2#,>2H4B"!:6.<90.(%5!505$:=:)?
@r5927
CNTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTT
+
'"@G%=(5F/;#981/9A3+B"?3$9E%F+D:2;.B97>+;,/"E#1(:.'"D29,
@r5928
TTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTNTCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACG
+
G0<+6=&/=%%G"$&"!F305"":$$($")'-:1F159.H5.F8&&&?EG"B"-=9)DEE1,A91'D+$<B)F%G6#@/@2#?)B'!1F74C(G&=F>>538$2!;?F"6>;4#F@:C&9)8CFE#'67<*E/B=F-E@9G#<)D76@"</>2&3D+$==31%;"7)!H@;C5?D@?#=?'D/"%&09@#0B0/+HEE=00-A(,
@r5929
CTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTNACCGGCGCTGAATACACGGGCGAAGAGCTGGACA
+
C8&5@E3:)C&#&FH'2@=;A>GD82$*;1142*/8!9H.:4>2*87%%1448B5&?%>CC=/B,&-5E%/#5C=H)-8H+8-8-05-)'2=((3+C-3CC6*!2%;>7!*==CD'4::5&3D@
@r5930
CTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAG
+
45A;E-6-:F+<%?;+7).8;17$,:-;%8C,>5D76<<8@A%!+
@r5931
GCNANNACATCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGATGATATCGAAGCCTACGCGCTGAACGCCAGNGGTGTGGTGAATATNATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTNGTGGCTCTAATNCCGAGCTGGAGACAGCGGTGAAAGACCTGG
+
$**'!!#(+(!"$)"%+'#(!)'*)*(+&$$$"!)+%!"")(%&'!*$($&(#)*+(&*'('"!)$!%+$#'$$)**!$")*((+##$&!*##*+)('+!(%+"$)($$*'$")'&*+&#+%%&&!'!&(!&&$""!)"+*%)(!!($%$%!(!")+)$$%&(*!)''"(('"+++)!"*+)+*$*"$%)(&$'%+*)"$%&'''!+&"(%+!%#)*&&*%$+&)#""#'+!*+*)%"*!"!**"!$)+"#+%&+$#$*$)"%!)$&+(+#$#&("'(+)$&#(%$%!%#"'*&
@r5932
TAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAA
+
(;8)$#8<.*0.95G>'7D$.%-=-8BH'F,*;B(8+;04,+<
@r5933
ATCTATGGTTNTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAA
+
#$(+!'&"(!$!!)''&"'!'$""+!*##'+%$)+!*$"$%*%*&()*+"*&(%)%%+
@r5934
GAGGATGACTGCTGCTGCATTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTTCGTTCAGGCCACCTGGGATACCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCATCAGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGCGCTGGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGTGAGTTACGCGGCGGGCGCGCCTCGTTCATT
+
C),D(E)00:=8-=7$'?7&C26A78,'HH=3G<::0<E@58>""GD@-AB014"B;C%*CD05=%,&>>)3'D;"0'!H558"EC)!44F:763)$3EEE6B<A@$>0#F>5.4H2;"D,<:87;#,A)AG;8$/3A,%6340&-;H#';+2(3B/!>5<2&8G40G()@"$F#7G>;@6+DD247$#!8)6"2#HF2'E5?)>1=AD<E5("A:G98;>8FBA!3>0%B>:/+6'/'!C1=,'HGAG/77A?17G;$3+E4+D/2(#H/*(59F>28A"A=<,500:&<736)&937&DD<4*A/')6-$694DD.D;,@708!*+(%?1*;!B;/.<>/!0$
@r5935
CNCCCGCNACCATCCCGCCGNGCGTATCCATATCGAGCAGAATGCCG
+
("$++##*'&($+!($%$+"&*%*'$(%%(&#++&!*"#*)!'!+'%
@r5936
GTATCAGGAGCNCCTGAACGCGCTGGCGCAGNAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCANGGCCGCCATTGATGCGAAAAGCCGGG
+
,64:B*:=,"*3#(F4?/,/BD2(7AH$=*/0-8H2B=97..>;G,9)E:0+(5$.+H+>#;&80?DB<D#>*.183G.3-D/!(#C<"29GH,8&</
@r5937
ATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCNCGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTGGATNTGCACTTTTCCGGGCTGANG
+
*&+$%+(*&"%#++!"$(++$''$*&$+&"+$#"%#$($""$"&%#)'(!*+&'*("))+#$''(##+%!%$#!$!#(!$*('(')+(&'"")$%!"%+")(*%)#!)*%"'(&)')!#+'%+)+*&#+
@r5938
GCCATAGGCATTTGTTNTTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTANCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGA
+
>(+>$'F<=*E?H4@:))#)<&/C@72:HE#1&BB@FH#(>1.:E*<54*5H-;B(<'&B41E6<39;&";D<?EED##'+61!F&14G4A=A<25B!#1
@r5939
CCCACTGGCGACGGATTNCGTTCACTTCGTTCTGGTCACCGTTAGCCAGGCTCGCCGGGAAAGTTGCCAGTAACTGGCTGAACACACCGTTGATGATCTGCGCTACCNGC
+
6//7=3(0&9.7958C1H!A54)(%"5AF;$*/@7<4"+0(/C26=E55*?3D7<35F*ED!B1/@93A7<+,GD0$?<#)=:D,!.)',-DA,%$69'5GEE,<+.%F8
@r5940
TAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACANCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGNTGGCAGCCTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTG
+
G02/E3H%F35?42FH>D*/-,H3&'8/DE3)/1+:2B5?3<99,!9)1.%E!:<G66'*&E%HH20FA%55!*>8&3)676%8AF%5>:*>8":3%4F7-&-)+89=.ED"7F/A!%"1.;1H.?<F-B946!#C<:B-B8)5H0&E1B&32,512;'9,6<$17=G2FD((63E'B0/,991G'(,#;*E:H>5(>09)"+'.)C%-FD6180,1!;3*C3,&,@9B
@r5941
CAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTGAAAGATTTATCGCACTTNCTCAAATGC
+
0@;:$@.%52()B+3:E'B!8;&<9C=H'-$*H7B+)!'56/"@G9:%D--)'=/(G.)CH,-<>,B3"A02,2':@FA"A
@r5942
GCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCGGGT
+
+('+'#"+#$')'$&)''***+(&'%#'$!*')*&(*&*!+)&+)$&'"%$%#+(#**+
@r5943
GGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTG
+
/'(0'@?,GA!.>@>5<'22((<4B@(@;05B;HEHB"2@!;#433,=;E%:3>8.:.81?E(6D=C8-E6(,F8?A7*71)@!+6*++=39.'
@r5944
NTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCANGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGT
+
"77-9?-=+,<#)GAB168-("<4*@*E#$#(''))HCB>D<H7>F)C8?0,(H@H5/B+:&2-6/:=A%A(,,50/6$H@9:0D'C;$CB4&&+F,09%71?5B($C20D26&EAD)*-:<(B$92/
@r5945
GGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTAT
+
:,?G01+7:<1/3.#+3A9,GB+12"/)E6D;3FD5#3-F,$-!"+!;E
@r5946
GATAGTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGTCTGCTCCTGCTCACGANCCCGGCA
+
&+%+&+('+%'(&&')(&"+!*''&$#'%+))%"&&(%"!$+*!*#+"+()!%*)%!#+**!*"*)$%")+$)'(&+(+*!'(!&++!
@r5947
CGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAANGCGATACGATTGGCGGCAACCNGAAACTGGCTCAG
+
&67"6A>75D3-7!:FC$9/G8=A("3!BB6*+!A">'/1%?H>7H<(,A*4)9*%@9,.;"+0B!2>C-AC4:+*,1'/6
@r5948
CCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCA
+
B7%G@8+D+%H4(&9/:=E!8&:2<.D5GE>3<@7/7458)<G9E.%0=,+%,E<<8?6+(6H'/E"-C%:%=>%<76)&A
@r5949
AGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCNTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTT
+
"<;&.2,'@FF;6@C=?$&>(8"H(%5DAB;?#F-*%EH(9G7+/,)9)'?2H)'H1FH59C93/CFCD?680.G@5(&9*8(CB)2#700%+G(AB6:7E7'%>'!3$"%)95"/2>.4A"$1;B*8')?27D0B+=%*@B#8%5=88,-E7(:+0:-9A1A6&94F&=*&>A33CCE.='.$0(#
@r5950
GGCTGTTAATCATTACCGTGATAACGCCATTACCTANAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGANGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTANCTGATGCTAAA
+
09B4%/(.(&0D6>H3.?')=F<4B(4F+0F9)"%9C(5%1$F137G$:0G'7DH7)7?20@0A,8A87%#-5C4+7@#=/,7>E<B"58*8?@"8&<G/2+4A;&!1<"*A!0)%*H-+B-'>CB'"/()B,0"C-0#5?6/G/"EF;@<@.#?BD!%C"D'8$(
@r5951
TCTGCGAGGCTGNTNTTAATATCTTCAACTGAAGCTTTAGAGCGATTTATCTTCTGAACCACACTCTTGTCATTTGTTTTGGTAAAG
+
-D5DD3<D4E>!72-$1F;2!@G56=AD7>-B-9:-E$'E),C?G($2D=&,E#ED81*5<<&,:50-CG>D).CH=5HC&D@2'1"
@r5952
ACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGA
+
6&0!9&7;<1B.??6#.,B"$=>286),&-9$:0#,*&7<@*DE:+0
@r5953
GATTTCAATAACATCGCCCGGTANATGGCGAAGCCCTTCTGCGC
+
1,?A$@#*D5>H4:@HDB@=>H/D$*9#=;%.>:159;&)=D6,
@r5954
TTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTATGTC
+
/,3?H:(*=4@";)B6>FD8F0<G):$&&=+B4!D?-!;E"(10#>8(=3$:
@r5955
CCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTAT
+
B/#8:7+.*!?#&"G66G>@(6F$A0&3%4,"30-4+5:D366CC,G;G"B6D5$
@r5956
TGGGCTTAATTCCGGGAAAGCTGCTCATACGAGACACCCAGACCGGCAGCGATAT
+
-+*!0B8*>&:36/2?2!B@6)G6@%4@9B)#)F;/B,3::"0!54)0F$3663*
@r5957
TTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCAT
+
=-$/)&;?A4!FG@=F/(+-)G&',HB=,+G"=(:?6+B?;!#F<G1F/:"6>):,*/((E%A7C;.""9.&?F?<:/G8@A:
@r5958
TTGACGGCGAACAGAGTGGCACCGTGAATGGTGTCACGCCGCCAGCGGTGCNGCNCCTGACCGCAGAAGTCACTGCAGACAGCNGGGAATATCAGGTGCTGGCGCGATGGGACACA
+
9///H?H)@8G=G?6.'4D?"0>:6871HE!.5FB!?&>+<24.;?.@E/H"=D;))8AB*&3D%1+9#081AE-H7%-<+=-94?/GC9E.:++H9&E,G(?.&60$1,,E=96E
@r5959
TTTAACTATATTGTGAGGCTTGCATANTGGCATTCAGAATGAGTGAACAACCACGGANCATAAAAATTTATAATCTGCTGGCCGGAACTAATGAATTTATTG
+
/"E%$(<*;4=5D&:?.39=6/::5#63-2C:,G%H!/FD(1*0+B3((1<<CB/06B11EF6&<75E'2<H)F;.:'4-=BCG4B"7D*:3>.*/*$H+D3
@r5960
AGCTGGTCTGTGGTGCNGTCCGGCGTCATCCTGCGCATCCGGATANTA
+
+%'$$')'+)!&!(+**!+#''+$!$(+!(&"''##("'#)&(%+($&
@r5961
AGAAACTCTTCCAGGTCACCAGTGCAGTGCTTGATAACAGGAGTCTTCCCAGGATGGCGAACAACAAGAAACTGGTTTCCGTCTTCACGGACTTCGTTG
+
E;+/?E)"4;6E=;.,8.5?C)G433BF0/&2#6H;.B=5:<!&<.!5(6(4?!#E43A0.+(DBG2+1?+,@4)/:"D1C3E@(F,<+&#(-5E>('6
@r5962
NNNTCGTTTGGGGAACNCAGGNNANTANCAGTTTTTATGTTGAAGGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCNAT
+
!$"$)')'#!##'&%$$)!(($$!!")+%(+%%)+*$%&"%)#)#&$!+!')(%(+#*&*&"+*''("'#(#*#%%$!)%&#$)##"*()&&()$""+!"$!
@r5963
NAGGTNTNCCCTGTCGCTGCTGTGCGAATTTANCCGCCTGCTGCGCCAGCNCGTTCAGGCGCTCCTGATACGTAACCTTGTCGCCCAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTACCGC
+
''!%'")$!'#$*("%"'!+$$#$#")"*!')""%!+%"*!%'()&&)*+#&""+*$""!($)))$%$+&&'!(&"*#$%#)+*#')(+$)#*&+"!"$%)%&(#&%'+#'+##*&)#(*(*'!#!!("%#'"#""!#"!"!!!)"&*"$#')&%"*!!*($#"$+'$)+*"'&*&"***!'!%*!"+%)*!%
@r5964
CGACGGGGCTGTANCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTG
+
+7<BHA-&,(?'>B)A7A0".*(9!#=$05*(,C+,F,9FEC9G--;$B$(*!5*6*9"-D8*CA=.:=&8$H*>*DAF'2A1G-&A!2-6<(?1DCA"<5.797(+$C+'5<+'/(/1"8F=?E$$:H%7+F1%)%:@,
@r5965
AACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCNACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTNGATAACAATTGATTGAAGGTATGCAAATAAATGCATACACCATA
+
@.H"#=:9=$:!*<<!40G$)HAA:4#G(=)=(:H9#2FH'H;@9=G3G5%!"+*3#F55&:H0B8$9H7*7055E@(<G6E1*@B-BD"$%9:&F;D":.2&"@"/7@HFD87)2.9;":@1E%)::-BD2F<:B&*,GAGH?'G-4(5+$2#,'D82":@$0%*.HD;%B;#//',85/B;/99H/.?353$;G-6E3%B0F1BA#A:F8='*7E4.825>F)B&'/@-:$71?2H<?5*,33'%.C*
@r5966
TCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTCTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAG
+
=!?9*C"";<&#E)2'"#3!2+0%!%#):E98'C6D33;-H4,&541+"'C"2H5CAD>%/0+"?3#2D*%C%&E(.%=&)@"1./%#=%-25+GG,=4FC"9:-3E3'*.>753"A@$-$<?6+6.+CG5,(9@'BE*7@=;??37F:1&A37!';&&D0=%D:/11#%"082!.05H2;B%6352<HG"-?F=)2/
@r5967
ATACNNNGANNNNANNTNNTCCNTNTNNANTATANNNATNCNNNNNAGNANANNTTNGNNNNCCNNNNNTNNNNNTTGCNNNNCGNTNCCNAGNTGTNNCNNNNCCNGGANNNNACCTNCTNTGNTTCAATGNCANCCNTAGTNANNNNNANGTNNGNGNNTGNNGNANANCCTGANNGCNGTACGNGNTACNTNNATNNAATGCNNNNTNNNCANNANTANGTNTNACNNTANNGANNNCGANNAGCNNGANNGCNTGCNCNNGGNCANAGNNGTCNNNAANNCNGNATGNAAAGGNNTGNTTNGTNTCCGNCGGNGGGCNTANCNNNTTNGTCTCNNGNTNAGGCCAGTNAGCNNNAGNGNCGNNTNNNNNNNNTNNTNNTNCCCNANNNTCNNNATCNNN
+
#"$$$$#""#!"$"!!"!!#$!#$""!!#$"$###!!"$#$!#!!""$$$$"$!##"#!!""$!!$"$##$!"#$"$#$#$"!$#!#!!$#"""""##$#"!"!#$"!"##!$!""$""#$!$$#"$""$""!#$!$!!!"""!$!#$#""$#$!$#!"$#$##"""$!"$#$#$!#$"$!!##$$"###!#!"$!##!!$$"""!"$!$!!!!"!!!"$#!$"!"$!#!$!"!!$$$####"!!!"$"!#$$"$##$$$$"!##$#$#"!$$""!!$""!"$!#"#""!#"""$#$!$#$#$$"$"!#$"#!#""!$#"$"!"!#!"####!$#"$#!"#$"##$#$$#$$"$"!"$#!!##!#!#"""!#$!$$$"#"#!"$#"#"!#!"##!"!###!!!
@r5968
AACNCTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTANTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTTAACGGGGCATNGTATTGTA
+
&&'+("$'"!"%($%#%!'%"("%&"+&*'#!!"%'*$!)+)""%#$(#&&'+%#+()#%*""**#"(!$'&!&('+'&'('"'("&*)+'#"+"&#%$(%*#$"%)!$&&"'$&+")!)$!'+$*)%")+&&*+)#*#)+!#**$#!"&(((*"$!
@r5969
CCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGG
+
/,(5A!B=/1*@<=(,&1'9E?&1-@3G-63:4!B;H?A<=/($)5>.%H&B?G4A
@r5970
NGNNCNNCNNGNCGTNNCANCNTTTNNCNGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCG
+
$!)&&!"&#"&##("'"&$%&&*&"&"%&(+$*)"!'+%&&$&))!*(+'!&(*+$&#*)%))(&%%(''$#%"+
@r5971
CCCCTAACCTTTATATAAGAAACAATNGATATTACTGCTACAGGGACCCAAGNACGNGTAAAGAGTTTGGA
+
#+)#*&&%"'!#)'$%&&(*'&%%"+))$!*(""'&"+%'(+$#')(''&%$%""*#*%%+*&''%)&(%(
@r5972
TTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACACCGTTGCGTCGATTNCTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCA
+
@#42&!9E.=F+5-$8/?4"!(/>B'1/5AE"?8"4&7(-;$6!B"6="#"<(8.:816%F+8/5G--63'%D)?"BB.+!B8(:@GFB91*!FE1%F8.:E45B.;C$;>A+6B#D'75?F*9&B639'?/D6=!:*"019)HF//1*E4&*@?3!/*D/1"7$G)<*&)C(E,6-@B?$=)D9*2F:=@!!CA;@*:+?
@r5973
TACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTC
+
$BA"E5CD&&D:'6+?#?A&-;'?267B%F,B.>>.:-B24.G49%%06DC6<?;2:00=)H%G!$((#26>C.(
@r5974
GGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGANCCACCCCGTAAATCCAGTCTGTGTTAGTCAGGTCGAGTTNTGGTTTGCTGGCTGTCACGCCT
+
-D(:?C)3A9:)"';=GC4>>@/8;D(C&.B:.2D(-5:GHH(,=#%.C'/8="$A#A";%%@,:><3FA)H=)H"-AA14&&D20/9747,2'&,+!<<)*1D=#2-()?/HG4"7'(F,)>@14
@r5975
TTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGATATATGGTAGAGCCGCAGACACGTCGTATGC
+
0=GE@EG0*50E!"F%*7F,?#"*&,H@2A30)2>!701;4!91)%2(FD4--94B)GF8"7AH4B=+16'AC
@r5976
TATCCCTTCACCACGGAGAAAGTCTNTCTCTCACAAATTCCGGGACTGGT
+
6$G2BF>/)H7CB**+B1(-,G%$GF456;C!",331.C"*CE&-2#H4"
@r5977
NGTTGATATGGTTTACNAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAG
+
+!?)G=HD,"7G.#;4GAH$"?C.8G7>/4D2:=;F%(#11@=111F)$5<4
@r5978
GGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCAAANGCGGTCTGTTTTTTCGTCTCGTCGCTGG
+
5=BF>/!+F"AB>-'#-7;7%H9-,5B(D34C3&G40;G*AC:'5GEH;@BHCHA61%:>+573:$B>'>7=F?3B0
@r5979
ATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGG
+
:&9AD1A5"=44AB/$;:B")E6H38>E7H8076F3F:>>8#-C=!&!)AFFF*"F(%C2;?BD>>635B(8#:E+>"0B'7
@r5980
ACAGGTTGACTTAAATCGACCAGTAACAGNTGGCCTTTTGA
+
@""E7:$4+593;+=@'-52:-@3!;:G+6&5,3-4AA#&%
@r5981
CTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGATAGCACCCGGAGTTCCGGAAACGAAATNTGCATAT
+
$(%$)+""'#(&*""%(*"+#&"%%(%&)'+*(''&$!$'!*(**%)+$)%+%++%%)%*'#)%'+)!'(+()
@r5982
AACGCCAAAAAATATATTTATCTGCTNGATCTTCAAATGTTGTATTGAT
+
.$8!(ADG!G(>F=,*..;G(08=9%@,82BH*-3@DAG'4%&>1%2,9
@r5983
CAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCT
+
29"&'0F=D'>+(@*:C>7F=1E69$0*A=.0"+*@$17:D'('%F,,*2=#=(4#.E0+5/");,?9).?<)+!+.C"*40D&0&&/<1&:E7@+&;A="A;D!+?
@r5984
TTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTTACNATGAAACCATGCAGGAGATTAACACTATGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAA
+
?E<<&';+,=6&,C9,4H>!(4<(*%4<920%#"5HF!"(+-/1/E=5:;<?%4&$,A7G/;7.&-..8BH->%7<*(E.E+)E26CH>C2C;'<(@?7C0$=456*?D&(#2:AB4#E"F-#(B934/76B>+9BCE$1+@1G);'B('<C;"D&"G)B-:(>+:379;/=%BB51G*'G>&F4%?8A33"B*'&>?G;3B0!H0!'&A94#"9/A-9)
@r5985
TGGATATAGTCATTAAGCCAAAATTTAAAAGGGATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGC
+
9,7G4=925&CF56".FB.BD$BDAC!,16"6H$C!;5H14=6<"0>CE'31)%BA0!$H@D@;!*)'A@,%B+613:=2:":?*#77=B6;";4:#=%5F@E%,$";"+6E2<;*..'FH9('A*@@C!5":;!D3<'0/758=ECF8.)>G>(&6DEH??'020
@r5986
CTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTGGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCG
+
6>5F"#9&"-,!?G-&1.1:)&35>.+-*6$35:#A6!;@5)H&:2B8)<)-?!-)%*/&5$%"+=/D3()52G-/C@,1<21:,CF
@r5987
GAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACNGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAANCTCACGCCCTTCACCTCCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGNCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCNGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATAC
+
AB7,"$);(7++38E59B=3,E;@H'38:-51#-0@/(8&2$'0.)+7)>77)F'="&*/'F;B'9!94+A%-"%+A=HF1<A8-F.0<+4.@:?4*FFE&5.+($=%8+G$BG1=FE0C0!1,AE#*:*6F)?':B)B?'G6#3>+B#&+!A#*("'71(?+%$84E$9$6'/!DE==648$0,FH>;6=<)A<H-6<><"7D.)'/;':F()4(@"@&"H2C>-6'/,5<HG0&:/79C"(F2&'5!&-*;A)/*:4":&6>"!7.CDB!<8)4%0FCA(;B#@,<6H,;>)>$$9<%-09G2H3(9E2@D/42G
@r5988
TCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGG
+
9&GB+;!93E)!BG99/0?/G(($;"9#%EF#@$=G!.3+.$'/(C'&!#@6>>:/F,3,E6F?9:GA&H>F**9!)5/@H&077!#'A$<H(+A0!=C..1#.+5!G
@r5989
CAGTGCCTCGTCCATTTTNTCGATGAACTCCGGCACGATCTCGTNAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGCATTTNAGTTCAAGGCCNTTGCCGTCACTG
+
E<=*+9/BA6"1#,-F'&<9$7>)B+B)>&"E8B>1#5G8'9-;-C++)!.9=*:E(:D13/2@E#4D/&A3$$&DH1B=1C>#6F0B'?.=A%(C."*:>/+8)%/H:$/H.>*9=::91E<,GD+/!)C=47;$+&1)FC*:2:D+&<"/<?G(5:H55>*<4=2D<*E);%71.#-,'!9<<1#AA-@@)*!86+</.8%$4H@%+3:@@&,?)C!*(!F":?6@@GF,C@$"@A(1:+2>63-?3!?D?F7;4.G8C)%='>C+71*'5E/6H
@r5990
GTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTCCCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGAT
+
4D'9&-%>1(!;0'H.+#(>$"E04$>A$:D(+'-5480=@;A)3+;813>-CE**B",E2C;"5A?:=)4E13$:47/%8%<#F*;=**B1@#.C8$H7.=H.66E,7E,+F>03*@74H!%#
@r5991
AGAAATTATTNATCTGGTGAAGTTTTTACTCTGTCATTACGTCATGGTCGATNTCAATTTCTATTGATGCTTTCCAGTCGTAATCA
+
G@5>=E5B$AC?3+@"EC8E#=:/0(>!>,@>7'A0*C@H55HFF7'9<;18*$/:#"?!F9/8G>/&&!!'0805G2AH$BA6?7
@r5992
GTNGTNCCGGTACGGNGAGCAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATNGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAACGAGATGCGCTATTANGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACATGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTNAATGCCTGGAATTAATCACATTCCCCTGGTTCAGATCTGTACGTGGAAACCATGAGCAAATGATGA
+
''$**!&%*'&($$("&%'"!+%'$%$#)*'!%(*(#%"&#"$#+&'&+''#++!'"&')&)'&"'"#!+&(%#(*%+%##!+%!%+!%$!+')#)'"%#%+'"!+!'%%")$+#(!&$"&''&$!!*)+*$"!"((&!%#&!!!'$%*(&&"++!*"!#(!+$#)%'!(&#!!++)*#(#$'!*(('#"%%++#'&#'*'$$!+'$"()"+#*'%"!!))&+#(*"&"(&#%!(&)$!'($!!"**+$&("(#")#$)%""!&$%!)#"#&(*'&"#(#!')(*(&('#'%+!!!))&$&&"*()()%)+++)(+#%%($$##&**"%)!!$&#))!'''*"
@r5993
TNNTGCNGTGGCNACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGNAACACAGTGTTATGACAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGNCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGA
+
$%$%%*&%#(")+)"$'!#+%*"!#(#'%#(("%(%#&)#'$)&"+)%"&&'"$+"!(!$+'$!(*!"+%(+*)+'+$&%#$"+*#')+$')'*"'%%!*#%*+%)(&%$'%$%(&")#$++$&%**"!&#$+$!*+'%(("!+$'%!&)%"%$"$+)#$*)$%)$
@r5994
GGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACNTTCCGTTTTGAGGATGTGCTCTG
+
*5D6;>DD45H6?,>@343?/9-38%$4A%'9@0827,+<E-.3EDC3@7&*-&>,EE)?F93)CB)H7H2H'H-'%,-2/#0'C=<B8E8%:3.G";=)+E'9H),'*"$&&;C
@r5995
TGCGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGAC
+
H<H(A,>B-%EH&;-4)4B6B@FH'3H(+80+((2'/5E;?55%
@r5996
ACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCNCGCAGACACCTTCACGCTGGACTGTTTCNGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGNGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGANGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTGCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAA
+
.A<F#'2C9*&.:3*@7D/*:3D4"?@CG#9,=;G@0+>:8*+0+0"?*44())?3+(%'(-H/1'*-;2D7$&F8;%:F%B%,)<-8=(;16!?87;,>)"*B"24.7?5+-!B#(@C3.8;#$H1>B6#)=4:*3C4A/6H=F3;./9:%/;C+(D@F?878,A.-?"G/<80%G$:=3#:+D9*1*)*66*(D4"<<96&(;#$3%*#=>39H,?!/6!&:G$G@(4<2&=01)D82F(G"#("?(A6051%BFF27*;/2>!::4:+GC9,D%2&5,=23H1F<!,1#*(BE##G@)&/$/83/F!E3<8B<$E,,26%,D/&$?'B/G)7&&9/:(#-G%26@EG?>2+2C37G?0:-(;)>B1E?1!%*B:@6CFBD8E2:$"0%(E6D2C41H*G6*9@AD)"0(.E<*)AE";E=A;&6%&@*FG5A",H6!CDD$:#D.:G8&,',):!,D3=/=:+%-/>4+91;+>;A"=:(@@"3),?A0:A>E<57>.1;=D(HD&:D,/F"295=A?&>A7G)(.2H5)@)'$&:#(:A"E4;A6H837$F!@,=:2E!FD*?7(-E1%295<<G5
@r5997
NTGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGANATGGGACTTGTTCAATGACACCTCAGCAGGAAAACGCCCTTCGCTGCATNGCCCGTCAGGCTAATTCTGA
+
+++*%)!*"#)('+&(#+%'##&%#$+&*$$'%#)(!!!%%((*!($&)#(!#*)'&(&)*")('*"'!*''*&'&&*$#&%*)+%$)##%'*+()'!&"""**")*+%$+$#+)'!**%"'*$**%&+$"%%")"
@r5998
GCGGCNTGTCCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAA
+
$'""%$!#!&+$!$%%%()&%$&!($*&"'%+'()'(#%+%(*%#*#+'()*!*"#!)%!%#'&&+(**
@r5999
AGCTGGACTTNAGCCGNCCAGGTCTTTTTCTGCTCTGACATNACGTTATTCAGCGCCAGCGGATTATCGCCTTACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCC
+
")(((*!#*'+#+(!'))($%%+$%+%&()!$('!#%'"!)(+%+"**(!##$+$!#""(&$)!%)%)&+)'+$$%)!$"$++*!%(""#)%!(+*'")$"&+'&&++%&(')%'(&($#*&*!+*'#*)
@r6000
GCAGGCGGCAGGGCTGACGTTTAACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGC
+
-'+)/E6E2A-:AE0+)$@DA1568E>7#6?(#;):A<&44E6;#(%2F*'!0D9)E(>5
@r6001
ATTTTGCAATCAGGCTNTCAGACTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTNGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATC
+
'4<!C-B:F*88E'<$7.4B?-7EF:.>!%;-H:A.&$(E:?'DH&"E74%';$.,G%B")F'$;1*,;-903>4>*9?1#4(:3F-*./@.>+7))?AE;0.=;E#07C9D"8<B-9B3>7?01")B8D,D*&#)5FG,!#F>7H6E',#?6A?0!;1;*F;:.@#7"@5+$"BF-,3>5;&A:07"6"*$"6:@FB):4DB+?G.G-H?>-F+,'@*E+'F":E!++;E$!-!=%C954AC10%/H<'/&EB+<A%)2#'D+F8!2?2*:5-;1GH59+B30B66&4>!-(FA?-A)'+6.>:2H7$A9/
@r6002
CGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGACTCTCCGCCNTCCACAAANCCCGGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGC
+
;E)77C2GB&?!4<:&*+0>83@26,DB@)-;#%(2?95%4%,A&3$*5!<0:&=A2%8D!)9H'97)!2DH6@8*)C0A(D8"?E?:AG!?(<,7
@r6003
GGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTG
+
H3D$@C9&81F/2E28$:."!+*C2+';"7='2&2D16/F&>G(2'$:%"D83+<:8F#<$,DG('!>7*6
@r6004
NACNNCNGGTCGATCNGGCGTCGGTNTCATTCCGGATTGCC
+
"!'%"*'*'!*()%##++*(!)!&**('%&%*&!$"#!&*$
@r6005
GCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAG
+
&,4B)H92HHCF%B'G'8!B=#+##A*1F7D-$2E-*H#A/0HA+4;56A;6@;H/"14<'
@r6006
CNACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGNGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCNTTCACCTGCCCCCCCTGTTGCAGCAGGA
+
(&GH(E!B>2>-A!>59('EF44:$&%'B/,;6#5??A&"+%!!1E&',@)'GC+1<>!/29A4#(&/,D;2=;(49/FB:!?;>%=>D%0185%@>55:+9(!).C6&8'EBD?B?A0.":.%<0!
@r6007
GTAATCTTCCAGTGTTTTCTTGTTGNTTGCTGCACCATCNTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTNTTTCCTGCCATCCACCCATTTTTCGACCTGCCCTTCAGCAGTCAGCTGCTNCGCTTCCGTCAGATCAAAAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGANTTCGGTAAGGTAAACCCCGTTTTTGTTNCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGG
+
+(*!'#$+)(&)+$%$'$)('+!'&&''&+(#!##(+$'*'*)&$&)'%"$"*%#%%&)(&*&+!#)$+&)*!*$+!%(*$)"++$+')$#)*%#$$('((*))$#'%%'(&)*(!*"&"''#$""+&"%!(*(**"!*+(+"+%(((*$!(('"'!'!(%#$!!))*""(%&!&$%'(!&++")'+&$+*(*!!!"!)%**%*#$')()(#(%*%$#')'#""""*'"'#"#*)'$+&%#$!$"'((('%%+'*+*%"#%!!")&!%(""'%&%""*$%$#'(+!#"&!")$&!)"!+)!'$!"(!###'+&*%()%++!$%#!'*"$(!)+%"'$+!'#)#!'*$%!''&!$"!$"$*!*&'++%&)$"!!'$"$((%"&)&+#&#&&"&!"+'+#!*(&"%+('*+&%(%*"'&*
@r6008
TCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGT
+
E624-:&.)BG8/9=!$+;G;:>:)"D*%'$56F2)<!-?42@&"17;,1;/D6,-<H7772,?!97&"4!F>
@r6009
AGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGC
+
A"<9/)/GE=(=3?40.C?;;@1GB,3.'2175@.#H;72,E/D%
@r6010
AGGTAGCGCAGATCATCAACGGTGTGTTCAGCCAGTTANTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGTTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTT
+
7@!E7:D$71&+%$EH=949>*$AG?'?8=.-4E%-3<&"3+/4*!#9<&G>&H;C?B76@A&)@%%?7B?8/+#7D%9%,$<-/65E-1'*;#9F/?,;'<:4;:16-?5H0#)><2+@=6G"2C1#-A3<%4H#,/>8E'DD3B<HB8>;
@r6011
CCCGGATGGGAGTAAGCGTATTGCTAAACTNGAANGCAAC
+
D#FH+45,>3/@=&2!5!*B&$9(13!FB&*6/?(H*D94
@r6012
CTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTT
+
2.6$12!;<+<8=C%D'9>!D9!>8"5<H5EE-%G#*+!F4!1-93
@r6013
GAGATTATGTACCGAGGAAGAATGTCGCNGGACGGNATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAG
+
F?)>9**9922$<86A4D5#E#0?=0<@6/88C"=/B0-"@@H/1;F0)D,4"!B/:2!(B1&%&"087320564<D?/C-;-2?!C*E4=5>*B?8B4$-
@r6014
TTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTNCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTCTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTNCTGCTTCCGGTATTCGCTTAATTNAGCACAACGG
+
@G%!<(!>95CEDA@0-@8-"$$-G@.3=&>6:8H0*;;B1E1'<54A:CA#&)H*43$8!">::<@G-A@@HA2&(-4>)7"C!3&/*977<8;14;&11',(>1@>7?*B3<6$F;<,??1F2D>C$-/%//H$.",F"6.?FC1*F;-A9&>()8C?.H>(4F<B=B$--)>1&"#-24)A+E4%B</$D;.@%?".5"A7)B:-=!B3"*<;:>$2E*;8,"7;7@(955-#
@r6015
TCNTACTGATTTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGNACTCCAT
+
'%&(&$!#$)$)(+*#!+'()*$#&"$#)+**%)##!'#!'!$%')%(#(!&&&%(&!&*)()%+(#&##''(&#$%#&*+&"$$$+*#$(#!*)%!%!&$"#()+)'$#$+!"+%%&")''!"
@r6016
ACCAGTACGGCCTTAATCCGTGGACGAAAGTAATTTACGCCT
+
HFB?D69F*,<-+/$23:;*&-7DDEE3,+%5E6)7'7?FE8
@r6017
TGCATTTATCAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATATGCAATGCTGTTGGGATG
+
DB#*@3?-,!:-GD!G4D,/28/;E33@%D=B4<A&($?:6F@G;:+5.2*3:0?2F.A)AC/(<
@r6018
ATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAAC
+
:;"GD<7&6*GBD>GB-:A43;2&/<2,AC69*)CF9CD17
@r6019
NAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGTACGCGTGCTGGCAGAAACCC
+
%+(&*&$+'+*!%%#'"!+)'&$'%'+'%)#%"%"!%"())%(")#$**%#!)&+$*'&%#$$"$)*!!+&*++')'"!)$)!"
@r6020
TACCCGCAGCGATAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCTTGAGCACCGATAACAACCGGATGCTGG
+
5=>(%=1(C("!'-*97/.$@??G2B?!6.C+;84G!1-2:.&60>(<E/.H7B9249,$5*/E3?&4@4?:;(#;.=FADDB;;2
@r6021
CTTCAAATGTTGTATTGATTAAATCNATTGGATGGANTGGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCNTTAAAAAAGTCGTTTC
+
284$+%B</:@5=):=F5$10165,B1180G+0$DHB5<#69@C)E5C,08:GA@GG.GC)??@/'4:-.';,4H(1>(4!**A;86.-B(),/7?'
@r6022
TTCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTG
+
5%E-:'!>=..BC:!6:*5GE1G36"!&$!.>5&C?5::>>/:?9A?85,:##44!)+,:&@;41395>*F9""7#D>!6:-H!,+.=?G.()>?5/145%&H#7!B)9=5"1?'G81*'"*-C1%;=B53.'%5&A.9
@r6023
ACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTNTGGAGAGCACCACCACTGTTT
+
G%E,;)7H(,G1B>9&#CFF%9$"07!C-<HC$B"/-7-(H>&H>055/&A"A=9,2
@r6024
TCCCNNTNTTCGTTCNGNNNNAGNGNNCNNGNGCGCNNTNNTCTNCGCGGGCANGTNCANANGGNNNATNCCNNNNNNGNTNNCNANGNTTNCNACNCTNATGGTNNAANCGNNAGNNANNTNGGGCTNNAAGT
+
"!""!""!"$"!$$"!!""!"$#!"#"$"!#"$#$!"!$$!#"$!!$"!$$"$#$!!#$!#!###!"#$""""#!""##"!$"#!!!!#""!#$#"""#!##$#!$$$$$"$"!"$"$$!######$"$$!!#"
@r6025
CATNTCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCANGTGACCGGCTCACCTTTT
+
?1%!)/GF4&$('#6(C.+0$-7B3,6*@3H&<.>03A=)*D#$C).@1=<F55!!7:=87';H@D=16A+H?91+/,.$%G#.EGF<$41*?57</=2!*8,$6*/8B+-EH"=E%1B6>B),?3+$5B!.FD17:9</5:/)4-+B(FDAF'
@r6026
CNTGGNTGNNCANCGNATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACCCGAAACGCCGTTCCCGGCAGCACAANTGCCACAGGT
+
&&'*#&(%!!#*"*#"&(%+&+&!%!%*#"(*&&)")$'+#++*'(#(((%#%#()*)%#('''!+)%'&)'*#$%)%#'+#"'''!##"+)((&!)#&#""$('&%!!'&&$##)*%!'+!%"%'+%*&%$)&((("(#'*!&*"'%)#&*#&%#()"*+*)%(+'*)'$*"((*'%(*#&'(&#$!&(&*("'"!$"+*$***&$&!(+%()+!))*"&)!
@r6027
GCTTCACCGGTCATGGTGTATTCGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCA
+
1ADFEH#D8>9*92/4?0#(*;*2:D2:4(A'G7F5'CGF)'9&<'#!0/?5.6<1#D6!)H5#C2>>)=B/=(9#
@r6028
AGCAGTAATATCGATTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCNCTCATGACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAAGGCCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGNGGTGGGNATATCCTGCATTCCNGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCACTCCTGAAG
+
+(H"$&019D'D0!A$2"#B09$A+-1/&B/>?$G=04?A4-5(D;#'H256A):5+D/9G$G3313&.(0''3,<20<50:9=)CEH+5%0;A:)<3/(*6?3D74<H$$5<!25G$/&A%3"9EFB($$9;.$A)DC=AF>;?8(!=@GAAH82<=0#!*G;5,4GD$,FB)C!>=%6;5="A=?F%+12;3??0)A&9&'7/;'0-F466%?(F;;<,'4@6B.H&34(;&3/%3)6*=/&<<"69G'-)8//;E2=
@r6029
CCAACCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGA
+
7>!?5$)=#5(!B7"1;%E.;):C7;$0(*7E.,(<0'6!G*,7;A=3$6<%4:;>.)A4+D>$B(0E80$H<:&7%H<#FC9C.
@r6030
GCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGC
+
#4<9#?@DCBE%="C&F55'=:)G-+$1&#)8@2D>-,B(H""D,>'
@r6031
GCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGTCCGCCTGGGCGGCTGCAGCA
+
D6/<''13D?&$@7%G!1+')$?D+@D//?CH7:#.G=$*6)";2D;:>7$D*:9&;-H0")GD-6C
@r6032
ACACAGGATCTCTCTTTTAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAANTAGTAGTATTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTT
+
,$HB/1$'#G*<H'G?6@B36!%".:1B?508,';#<%?AB)>9C!/<3==D5372D)0@F46,719.D$3:6D:;!>=H;+1")!A@,GF7(,4)C?#5FA@?)B47G61E,A9&,'AB<?
@r6033
ACAGGGGTGTTACCACTACCGCAGGAAAAGNAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGACATAATCTGCGAAAACTGCAAAT
+
%7G8<8A&@";@!A0">E-;0?'1@-H>/9A:2F?<(B?C='*7@;;'>6=&G'*D-95*,)D5+HC.E&/=FC<-@))A$:/C/2&@@<
@r6034
CTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGGCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTNCGCGCCGCAGGCGTNGTAAAAAGGG
+
&0B8E0'0<1>'4HD"#'&@*462#G2%'=%7?<0"73.9.BB!D#D$>:8$0A3/+1,62;-5F0.=/H'E#;*95C@7$21#,G?.2600<=@7CAC/!'+$'E@D&5++!'&A=D34@C>#2;6$D67@?0&%!+2C9!7$$7()87AA(@';27<5&84--FC!B?"(08242.<(1DE87>;<E-H/(>GH)(&*=4<(#
@r6035
CAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTNCGCGGGAACTGGATGGCAGGCCTGAAGTCCGGCTGGAGTGAGTGGGAAGAGAG
+
*H0<C+G$':HB7:>.-,'?G+)3=7;$&:1H2@%'5%/9@!5*'?'0#$<<4F=+'-@91902"DA$C"G=B068&903=3&#:?&.G7->+&8G3+G?G"!/8+G6<=&%9</9.(A-1?6;3*085=/7EB!E-,G97!@D(D!2HE&#/0>066;.E3H"BA.#??FH6D':7B6?7H0<85..&F%0:$5+B4>+.*.E/>!"+776'"CF$1#C0;;'9C3;>1B0$(E:)."#516&3FC@73"1E94))==%EC3H&:%>>92:7FG,55.$6:G1=#F>$.#
@r6036
TCTGCTNATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGT
+
'%(('&"#+'*+"*!%&#$&%+&)'!%&(+#$%+*)+"%#*(('%$%")&#
@r6037
CAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAA
+
,-)7?)(&74*35"031665:/?=72H$5C6<;92.2!9,-B)*/5:(D$FG&"&1C
@r6038
GCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACNTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACG
+
=)9"!')B*H6#"G;>@93-EG9",%#<?0(-%6-%FD%%4<5/*A(8B&C+,;64=$B$1#%*",9#3+$38><&<F/-F,82-H<@%D305E>(4@GCH3.6.A<>/>=.%D0*C2(4!-1<>@>2FB16"1/?%H(>=H#4HE@00@--7A=7*AD<3A?!
@r6039
CCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCAGTCATCCAGTTCCCGCGANGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTTCTCTGACATGANGTTATTCAGCGCCAGCGGAT
+
:%C;5(&F#E-=:;!$0<237B$<3.B',-"%8?D7D(,F6*%D;.4/0:*=1@%-!?E>2GH7."H:F!E@&+>:DF:C<G<*E71&(8'<G$H+%4'&0-<<,:3,G@A8A%64C+90G0)$;-%CC%:F-2=F>-!H7#FD*F'25GG/9'2:$#@2%/B#981&F#*//F"?=-:,&.+H1AH**7-BH%:(>16>G6>@:
@r6040
CGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACGCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTCCCCTGGG
+
+B!"+E)2-6@0G%GA.=5(&49''=CH=%*A#:/2'E'1#F?')B=#G9?*C==6,+A558,5$$;=<@.3#82,:>HHB;<1
@r6041
CAAATGCTGCAGCCGCCCAGGCGGGNGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGNTGGGCAAAAATTTCCTGTTAGTCGTCACCGCGT
+
(%)!*++$!!)#)$*((+$$))++#%(!*)+)##)#"!'"(&"##+$%%#*#(#"+&%&($&##(&$&)"!#+*(#+&+%%*)#!&("$&%()$*""+$*!%"$
@r6042
ATNTCACNNCTTGNGGNANTNCTNTNNCNCAAAACNGGGGGACACAAAAGACACTATTACAAAAGAAAA
+
*($!')'"!"'*&"(''$%*$$'"%&!$"&#&)(*&(+""*$"%+!(!((+""(!*()%%+*%!))*(#
@r6043
GAAAGACCTGATGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTNTCTCCGCCAAGAATCTCTTTGCA
+
(C'A%:<,C4!*E)&!$/F(6,CH2,:.HF5@.'@%!.=0=$5EC<!0#29-=@8(0$9@2$41,&-8+/44<2="2G<$&$G%%B3H,#28!H&<>C)B!(,+CC)854;;G
@r6044
TTTAATCTCGATNACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCNGCCACGCCGATTNTCCCTTTGACGAATA
+
H216;+1':!,BD&H(,EAH(54(#,H!@(&E;+<7:59&28F=695'FB+0?>C/(+/AGG'BG)-)94*<;7%1)289.!".1$HE<(29EG.G$-&(@+>%C<85CG=/(C>;4G!/<=$5E?&74;
@r6045
CGTCTCCGCGCTGGTTTAGCCATCATCTTCTTCCTTGTGCAT
+
%4>*-F=24H>4%2/G>89+8#4F<9)3<?4F2%0GG0FC-/
@r6046
ATTCCATCCTGTTCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGGTAGGCTGGTTTGACAAACGCCTGCCCCTGCATCAGGACGTAGNCAGACGGAACGATATCTGATGGCCACGGCATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATC
+
32?2E>@:>$$:"=!@1@D+G-#040'+(%H%)'9B&<53"5$"5'*.9*).)EHF,'C(5'4$0'7.(,!F7'E@H4/)$:4@<9D.+E7C:!<.&2*G':A839DA#-;2B.49048'1G($.68H0?/6'4CAE&9G<'-*,!(F&:E(,?G"@>5H32)G.>3G)9G*DF.)$=4*<7@H:"-@CB!/>C.6ABA=4-!F57C4@$:>7(H$.41,H$(;E.,<&;EE;.3:2F0<C%E=)
@r6047
GCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCTAGCGATGCGCAGTTCATCGCATT
+
6)B;4C1F<BA&"G.042'F<7C4?-B7*)6-;6-#.6'#33?A6$,.!/HE=0A*$H8;E,F(H?1);7<91-H%"%F/;!6C()@HF(-!F%A*%9H&'6&&,E?+<G.0&.)>0#/:@63%(
@r6048
GAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCGTGAAGGCCTGCATTATGTCGTGATTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTT
+
/1HB7B:$H*9AF*:?G?5;:.G'G,1*):E+/,=%.:E/G40(@<5;D2<:B0/0;?%279<-'&$D%C#AAG+?)*)!#'9B?6$@*6FF+.G0/'#9%);9*1,#F/F@F:="91G'9---":BF=2+5>=$B3+16E+$6=CF0*20<)&3";.#B)
@r6049
TTNACCCTGAGCAGGCTGTTGAGCCAGGTGANTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACT
+
#&!+(!'%'*&+++)((+%+"%&")#+#)*(+'*$$$)#)!"'+&$$%"'(($#('!!"'&$')*#+*+*')'&+')*#
@r6050
TCTTTCAGTTCTTCAATTCGAATATTGGTTACGTCTGCAAGTGCTA
+
D"%:)+E2GD476=2&6'GF1)41#),E#&*GB;&))6CC385:+F
@r6051
GGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCA
+
E*D%'4*?+<12E,:'/A,5)FF>H8'+3CC-(F*%/>!2!9
@r6052
CTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCA
+
,-D/<D(D827C;2BB@"3CB2-6!5)-$3#H(=%'!=D8$(.E*&>FE":D"D-H)+&334;19D,H;;=F-3B;+E=":>*H0.%C&8:
@r6053
GCTGNNNAGATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAAGGATTATG
+
(')&%%#++(&#$+%"$(*&!*&#+("%()##'&%++''&()&"$&)!"$%!(&''&!#&"#"$&()$"!+'"(&+&#()%%'&!""&"$'$)+!%'$&*)+!##%&*)$
@r6054
AGGGGGAAGGTTACCTGGATTTTTTCAAAGGCAAGATAACCGAATCNCATCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGNGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGNTAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGNGGGTATTGGGCTCAGCATGGAGGACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTNTTGACCCGGCAAACGGGAATGAAACGCCGATG
+
*(#!*++#'!(%%'%"'*%''*&**"!&%*'+$#'#+#+*"*&'*'*'#($&)$'('(!&*(%$'(%%*##%+!#%$!$)%+))$$'$#)'&$)%+%+*%&&$#"'$+%*($##*+*'"'&%(#!+*)"*+*)!")"#(&&+)&+"&$&++()*#+&+'!&##'$)"(+!(*$##*&$%$(*%%!)'(!!*!"#%'$+%&$$++)&#&"'*#+#%+##)"*!%%(#$++()'(!%+"'%+(%*!#*)+'*%"(#"&!%$()*&+'(!)#"&%%$$+)'*%'(''!%*'##"%+*(&!+!$)+%!')"(!*)
@r6055
GTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGA
+
D,%A0.FD%F>G9449$*.+)B*C%)0HH1;+66=22'&2B1,@$2+3C-0;=/G@?6
@r6056
ACGTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACNTGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACTCCTTTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCT
+
%("'#&"+'"%*%"#&!(*!!%+'$#($$("#$(&$''+)+"&")$#!*%$)(!$!$)$('(++%(*')#'%$$%##"(&'&&$%'&)(#&*+!(!*(%("%&"+)#'%*#&+*+*)!&!"*'+"*("&%#*#!%(%"+(&!#*%))#"*%(!'+')&&+*&)!)!'+)!!"('$#$#((*+))+&%%%++'"%)*%#*#(*""%+*(!!#
@r6057
CTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGA
+
H9F4+#/8>E$#1,+?53?/-%2&*F2%#+96B'>/6C(?33"6*D$&<1=5)+5.$C)3"3D#6H'#?<.:@"+A&:'G(HE2'%C$&*C+C1A#1;5?(;-=*F4.#@(87?E.
@r6058
GTGNAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAAC
+
)!*(+&%")*%&#(#(&)$*%(%$)*!+*$+")$%$&+&!!)($")"%"'""$"$*'&+#(#$))&$)(%"')(')%+'%(##"'!!"+#"*+&%"("%$$"&$$!+
@r6059
GTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCAT
+
:H!?!70/(4&&=2%E+-:$<2+83=H):3#7!C6DA$)@*A"1;,DH22CB!-
@r6060
ACCTGCGAAATAGCAGAAGTGAGGCCGCAGGACGTTCTCAGTAAANACCATTCCAGACATGCTCGTTGAAGCATACGGAANTCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGG
+
+%!(!')+'+)!)'$$(%*"#&!$'(%''"%*!'+&'!&))#'+#(&)&+("+*(&)"*')+(()%"&+"&"&+'&%'(%+!&&*#"!'"!!"$("$#)$!"""+&!!++*($)$"*&'('%))*'#!)!(*$"(+"*##*%&"($+))!&'(!
@r6061
GCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGANACTCAAAGACCTGC
+
FFE?9G#*412%;:#/4E$@#76(<H29-@#-A,?$?A2.C6=EAH:+*.C(9&9031+8?#.91<%#A30#H,H2:5(":5B59>4GH%&C<H2>?#B6(@8$<$=
@r6062
TGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGC
+
<!+B!2;2!85476=('B"91,&-#?2:>$,!/;+C4-#@5*HC"?5/<.A-/2-5-1=G.EG,!CG
@r6063
GGCTCTTCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGC
+
>4@<$(H*-C=@E&5$5,FA35D3,<>+-EBC>0C12',F;#,!(%4B/7<37,CG0C6&BF6!B#?:7G6C9596<:2.H%2E7*(2#+'>#=6F',E4DH);0406
@r6064
GTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTNCAGTGGATTTCNGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTATACGAAAGTGATTGCGCCTACCCGGAT
+
-H7$"H*C'48;;@A(-33"5FCB($$FFC:7$-23,*-@,D+A18G<670%&!FCC0@!A-06)G+6&D;&!2@#&D(E$>53$,<#=5F":-3D40,@0.)*5'DE->.-?B4%28&1@5E:/(H1;0.(E.>E4+@*
@r6065
GAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCNCTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTNGTAACTATCGACATCA
+
.&BA,4:D+)"(H108<#?.9/E:E@FG"=A=#5DAC),/2E=2=C&2$.?/5>,GEC.3,$7-;&"E0H%G>H6@,7=E'703G$)H"465.,*?"-58B7&#7:1!&-@9"1$3CB,B9E);F69%.2"0$7E4B/=E<3)@"@>(&0"86D495@D4G.::/>D:(1%5=9.@:G/DBG3?3FH0)8
@r6066
GATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCANCCACAGCCCGG
+
(.<1..A@74.;1/*E<GH2.(5C/,B=+"A'?:DH56;#40)=*C45&H;F7?90D+35$<@/+&"G2>E3%.98$C:1.#2E=?$+96DA9??)9!"7!F*C'7''D0!"7!/>=G*)1F;:=!45
@r6067
ACTTGCCTTATCCCAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTANTT
+
5A$?;71)?E<F"ECH*2%G@3;8D)1'.C:$9=;2>.A-#HH;'9BB8E@'2A#?="%'8+CDE*#@)+
@r6068
GGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGGACAATCTGGAATACG
+
A<)"5>HCF2<:)/9*:+'3!&&,"D#8&BG#)E:E9%E5"=H<911&AF597D2(<G1-CC-EFE.><)B5%H?9F<(=B+#*@7.B"11"/!
@r6069
NTAACCTGTTCGATGCTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCA
+
">$D,:)9-7FC#*!-%,";1E21/8"AHGG57$+:0;#3?/>A&B%%!!F4;$0DC9)B>..D(
@r6070
AGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCNATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGGCATACCNTTTTATG
+
;'(9%17?8=#8:-).H0=1..()5"'9)E?<05==27((7<D.,/),1A@G<!A43@)4=23FD*+<0D7/0&AA3+:9F=5$1D>A?$-G4;)G?$'"=)B.C)?;DC;0@/,@&CA@AG--$#+141,G$99:D!/?4CA+1GEB<5/A(&#3=DG'&!!!DG35)74%7,'4(43
@r6071
TCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGACCTCTTTTTCCGGCACATGCTGCACGGTGGTGATGGCNTACGTGCCGTCGTCGTTCTCATGGATACTCACGCAGCGGAACATTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAAC
+
#&<F/"2$$0E8E4/DF%C'$&%*38A)55>&.99<H@+:!AG)(!HA@.D;6H87F?@963@>8,/)@68=:&0H$F1064-%*!-."C0.70:*1D96&@,>0'76/%&.2/G3;1&+2/!@*2=!=##:!55'=C2:!20-65%9/;/:B;B33<46GHC<E1@#D522(?E%A2A4D)H#41#13*)9-:F?
@r6072
ATCATCCTCCGTCATGGCACAGAGAANATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGNGTCATCCGGATTCTCTCANCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGT
+
G%0@:(07B<4%<<,AA-@*'-?$"#,"@4"<==)BC+CF@17;<5(=6#&#F"/+D+F+;,77%&#;%7-"*A7#,#1-;:D!81E3(A!$<,'2C:9H99%>")H%AH:G+=+H?*C.D(8D'A7D@E.#$2'(3:F3//8AED57E++5=?.!+7,.@%!G@$),5:83-A@(!'A3A92/3@6CC#&@*F+*DB3BG+20#0/4;DH1@4<2:=@.D;#/"/3)3<?9&')25">=>6HC3C'
@r6073
CACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTT
+
9+3D';D;0H#($)/=:?73E+G>+'@E:A@$)#/%:7?(:
@r6074
GTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGNAAGTCAGACGTAACAGCACCACGGTGGT
+
,D79BG:#D5G"F72;C&@D95#43EA3>,84;3+/2)+-!5B;7)7A+DG-$;FD4AF;)!.:D7$%;&'D5.@',75-DED2"9'-9,>2F!7<09%)A"$)3D'CB-@6
@r6075
NNTNANGNCCGGCTGGAGTGAGTGGGNAGAGAGCGCCACGGACAGTATGTCGCAGGTAAAAAGTGCAGCCTCGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGGGA
+
!"*!%"*&&+''"&(&#(')'#"+)%$%%%)&%)+!'!%#%++!'')"(#*'%%!*#'(*$"%)#%*""%!)%#%$&&+$+$(%%+()$!&"#&*!(###')+!+')$+"&))'"&'%$'!%!#(&''*%+'"'((''$&+)'')!%&%#'"%%"#(($($!%+%*"+)!%#&'+*)+)'!&'!%*#(#"'!)&)&!&*(!#"+"$'("'*%
@r6076
GGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCT
+
5(95.<<1CEDH#&:7C(G:G3,C6:#9(25<,4;&+;4(D>5C%G=!1'H*4+6?E8;
@r6077
GTCAAACGACGCAGCTGACTTCTTTTCTTTCACTACTTCCCCACACCCA
+
,4++3=7/'$B3#5@<"""A+$<8A=>4G1907;38E?:/GA'+H>F!(
@r6078
CGNCANNTTCANCACNNAGAGCATCNTTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTNCTCTGGCATTTTTGTCGCGCTGGGCNTTGTAGGTNANGGCGTTATCACGGTAATGATTAACAGCCCAAGACAGGCAGACGATG
+
$&"**)(&$&)&$*)$%+#+*'!'&*!*"'&&%(*#*'!+&##%''!!$)&*'**&)("#+$+)(('!")&"(*$''+"!*)*!+)"&$*$+*+*(')"&#+$*(**%+(!"&%"&'$*%'!"&$$&&$(+*&)*$+%!!&"##(#)"+%*%"$*(%#+!))&&"#**")'+*%""&&)(&$)&&$#'%&$$!)+$")#%)$()+&+%&''+(#&%"#
@r6079
CGACTGATTTAAGNCTGGCAATCGGCATGTTAAACGGCGTCT
+
()(##'+$!("%!#+%!!%$$(%*%"$%#'*+!)&*$'*)+*
@r6080
GCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGC
+
A-4:*4(2E2G!?((=&>#:=4(0F?C;5?#;*F'!A;E%2&F;;+>(9(A<
@r6081
ACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAG
+
+>E7B2'0*F8A3F,=H$/07>3@AG$/?''A>983>1@/79+*35.)=-.=@94(:43GD9E(=;%:3=D3/;!3&;2#C9D.(A;BD
@r6082
CCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAAT
+
8&%5A)60+=2);DBF0<B*F#2EEA:H>#E1G:?7%E>7?&
@r6083
TATNAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTNCGTGTGAACCAATACTGAAAGAA
+
36=H611?"!)BC1E-E%G!:032)F8<'4D">F$/4#%)AF,B#6<?<5@D73A1F3F7/2>B57+-*9+1@$?:!#"&/H<4$A.8D(DD<1=9F.BE'/(+(.(E!.=-)267%G29948?&7."BC'C*8:2,E//>B73%G@8GGE/E$
@r6084
NNCNTCCNNNNANAANNGNNNNGGANNNGNNCAACGATANNCACCCTCACGNNNNNGGGNNAN
+
###$!!!!#"!$#!"#!!$!"!$#$!$"!"!$#"$#"$#!"!$"#$"""$!$"!!#$#"$!#$
@r6085
GCCCGTGCCNTTTTAGCCGCGTCGCCTTATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTNTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGNACT
+
+@%/9=@#0:G+/6H5>44G3HG0DG4#*@F:$%#G5<(3A5?B;4(6-@'33"-G,#@(;.GF?+=)98/CCE8&0%C0?;74$D.4/'50=?/E<G*5A""C52?2>8"<!54E01!;BB66?H24<DG(!@BD1C'"C-5+<9C9"?-?&32
@r6086
TCACGGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGANGCTCCACTNGCAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATG
+
'!%)!)*+)&')$+*"()'*#*('(*)!!(%&&"*!$$'$+)"+'+*($'%&)$&()%%+"))++!)#+(++*#+&%!!($$&)&(&&)$"
@r6087
TCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTNAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCANAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTC
+
(G?G(H/4B7;($B6'*'EA$-)>,1=B1'-A3.+:D6!+A6DEFA!;C5?F6>!:9$70'364G)A2)>5<0C>"&#/EF/)(!;*$"A'606:*G=2?%G"&:))460<@=+7<D;;BAD-*!5!><4<)>44.2E6!C&=<1B43
@r6088
ACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCC
+
CB+25HH+9GE&3-'D#:)05?581536!7,C8E&E+G'/5%668:=@F@%A#9/A;H5H!6;9*
@r6089
CCTCNCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCC
+
2"D(+B(*EEH=D,0,>%9,@-?0/1E2>@6FA@<=(--@D+52,&=)'=
@r6090
CTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGACAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAACAGATTACTCCATAAGNAAATTGTCATT
+
+"*(+(##)##$%*+$&#'#)!(%#!!$$$"$*(&'%('"%)'&$*&#+*$#!&&**"'%+(*#'+(!!$"#)$$()&!%'"%)''$(%+!&!*$*)#)((##''(%))!%&$!*"!+!$&()*'$#+$)*#**($)**+))$%%!*#')"&"+))+(('("#!")#$&
@r6091
ACTGGATTTACGGGGTGGATCAATGAAAAACATCGCCGCACAGATGGTTAACTTTGTCCGTGAGCAGAT
+
20=(37*5D,E<:*H81#73-')!7<2?G>19?0<@4%2-@F?F9/1"@<#*$+(5"'(C!9<H/?!,9
@r6092
TCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATNTTTCCTTATAACTTTNACGAAAGA
+
(F588!%"1CFH>3.>F%H?9E/C#650H*@'5:2;!GH>F3B</=?9'5:1+F3HAA14:>-G6E9""F"F:/<C?.)5.A,F8==#B<A&'H+$>3>F7C/A
@r6093
CTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTG
+
/ADA*0#&:%5E?"E=3'!,54++/5%E2)2-;(+(:3=A::";)><E3.AB.$%&)?/?&0%%7406*;C'B4(52$7??"">/C</HG7(;$##6."7%93=!;F=F;AA3EA+-E&
@r6094
CCTGATTGCTGCCTTGACGTATCTAATCGGAAGCAGAACGCGCCG
+
:0+:E-%DB:5#*'F/%.4G0D#;>>D4C>!H*6+#37-%.=2<=
@r6095
TGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATNGCCGCCAGTATCAATAT
+
D52$'@;<*2-B%C0:"95.CB7FG,;&'?G3/D#H9H@D)C;#:1:2G><.E%*8"E4##356%3;2A8.%2/4C9)
@r6096
NTAAGTTTAGTGAGTTNTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGA
+
$')!*%"%*%%)##*)$("+(')!*$$$+"(($"))')")"%)$$"+(%""!&!)))++$&'*"&#"
@r6097
NAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGNAAGGCTCTCCGACGTTCCTGGGTGATAAGCGTATTGAAGGCTCGGTCT
+
%%+'"))#$&#(#*+&!&$$*(+"(%"*)%#)+$$("%#'"!&&)'***'#)%$!('*)&+'&"(*##*#*'#"+"&)*$&##&+&"*"&!'())#&!()#+!$*''"%$&'+'!'$(#)"+&(
@r6098
GCCTGGGGAAAACAGTACGAGTACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGT
+
EG+B(+4=.4-3BG8E0-245/D%50)3:8/B'E'9/3BC,=F=8-AE>=7=CA*.GF=
@r6099
NGCNCATATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCNACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGC
+
#$&#$('(+((')+%+)+#%$'$#')$+$+#"+'&('''+"#*'$*#+))!"*'"))!')'$&&#"*(&*%+'+%+(&$*!("')!#!&++&$*$&!&'$%%**#'#)+)!('(!%)!"#%#""#$!')#"&+")"(!))(**&$#""&$("+&%!$"'*&(&*
@r6100
GTAGAAAATCAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTA
+
<+3%!*GG!,064+%GA)%-=GH,1-7.=0D!%&9&,,>)$@..F2:$3F"5%6ACD/'-
@r6101
GCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGC
+
<D&B"19:A+7F$(+?431G#.%.(%D"E$6CFD<,C:?H1,$/7E>;D(
@r6102
CATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCA
+
3+F(4896?<9")F-:5B5F9B6)A"+DFD(#'H#4.!11H4B'<G63")%=/D#96?;;#).()8$/8*6G6&5*<2C?:7HC/=DD
@r6103
NGNNTGTCNGANCTCTGTGANACNTGGCTAATCAGAATTTATNACCGACCCCAACGATGAATCCGTCAGTACG
+
')"$&(**!)(!*#*(*$'!"$$'(+('(*+%!$$&&&('&'!$'(!"!%+)'+$*+$&+"#$('*%$*!(%%
@r6104
GCCGTTTTGCTGATACGGCTGANGTTTTCAACGGCCNGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGAC
+
;2GF.@;@(,+0.)A-7:=9B.)E'#A9>?-08($"4E@"'A.1!2@7#(CA$*:-*,)8-;:>=7;,0')/=<C+BDB?<#)"GC3*6)(FB%?4.?A/E7A"709++?A67<1*0'2DA%=
@r6105
AGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGTCATAGAATTAACCGTCACCTCAAAAGGTATA
+
$*2@#0)?7"9CA@*&!7$'HEAHD@,4'?+ED6((C6A/-5E%:H8B-+E:GF$>A9!*B$:H=5!?=%'.%!A-$1D$*AAD"&A:!C0;89&-HG3G5B<8#@!F<@;+=8&
@r6106
GCAGAAACAGAAAGATAAACTTAAGATTCGAAAACNCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCC
+
+&:++$C(@*-#AG#F!8:7B#AA>34:/"7734!41:8>++C47A#/6C64@-096%>&D"35(2C<.>;(CF3&0:A4B+
@r6107
CTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTNTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGT
+
=!-"G)0,',98F32:>!4?DCGAB3E7E3;=$E=H=HB6H57'D=1B,/"G6>19B/'A4:+/87D%(AG.35H1=1G?.;C-E*!:+F9<(H6F+.FF32A>A@=GAE8,<A@-H"25
@r6108
GCGACCCATCGTCTTTCTGATTTAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTTTTGTGAAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAATNAACTCAATGTCATTTTCTTNAATGTAAGA
+
686"EE0;2&62--2A:C*H%+/(6)<8+,(+H?E)!2&HA=A,A;0%#-AA>&)A(/=?EDD2:G(@7!F/095B32D,"2/03$4)3B;:*A72+1'<&F.+=='E6(23#+)1:E6C6431-%H8&=C.*$1,8-2@@*H:?D52'
@r6109
CATTTCGGATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGA
+
(E7>33>*4B8;6(E!1>3FA<!@A?:7G/H48(%*@5(57D;<>A,C+>A"):>4@F$/*5
@r6110
ATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTNTACGCAT
+
5:+!:6;".;B(-B8==3.)1?:!'A-=9A;?/6,$BD=C4,%2BG-F%'7%.?<2%6H:D.@!?4&5>91!)"/9&
@r6111
TCANNGAAACCCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGA
+
$'(!"%#)'+%+*&%!$(&#$)(!'')!+))'*&#&*)(**')'%()!*%(''#'))"*!)!
@r6112
CAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAA
+
4@/E(D(14AB)H6#&AE<8C/;";=@<.>4AB"=9/HB&0:-/,?FF<+@;(5'7-C0))9D@#??@>+#;/H"9(+7?@#-9%BE@6%%88:F1D@%'=>0'A3'9-,'B@#C@()&=90("'775*,?2=C19
@r6113
TCNGTNNTACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCNGAAGAAGGGCAGC
+
!(#*&(+**'"%#($+*)'%"&&'*+#&(&!!($&'*$%#)+')(&$)#(+'"%#")!(")*$"'**)+)$"))%"!**!((!"
@r6114
CATGGAGNACACGGACAAACTGAGCCAGTTTCTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACGACGTGTTCCTGAAGNGCCTGACGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCTTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAACTCCGGG
+
BFCD4'4909&(E&&;+-,4!2B0C.E!B8A107<G(B#>G>%5F9D?1C>18&FDD<$5C$H,>;,@",-G)9'?'C;7887.<1#(,$/-.53$.?:;*FA?=516"-?G>$50@-#?,8)!,(#1G8,B34(<$9ADE+)<?7<01?65A=D2:&1>"#B)55AA"4#9?E9+#0A@7<#:3E3'%H4=%%H)7&9>((>19:8H9"4'>2H*-EHE$-G?@(0-47'6F+>0D$.E+8)/=4<0F(6A","6>4E
@r6115
CNCTNTNNGCATCAGCACATCATCTTCAGGCTCTTCNTCAGGCTCGCGCCGGTTGAGCAGACTGAAATCCAGCGGA
+
*)$%%(!%($(+&#*'!%!+#*$!%*%'%%")'+%($&!%#)#!&!'!&&(%"*&))&$%%'!%+)($)$(+!&##
@r6116
GCATTACGTTTTCATGNATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATT
+
19A!0*?A;7**:*GH,:,=/$E99?85C4$D@G?%)-A7B$3;=02GGA@@%.)A@,6.1?()C&H2D+9.<H7*24-;**(%1&",AAC8E>B2
@r6117
AATGAGGTGGGATCAGCGCAGGCGGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCAGAATGCAATAAC
+
"/$#()93'2#$($=?8!:1'8(4.)-G/A6;?&'CAA$8'H-,:HE<7),*"2#<'1':5#<2&!;$&1(--)'3DAE3'@0+G7*6'8D3.;)+:8FH;%*'G78*,EG524;-$)".;/%F?##B/HFC@"735<<G!D&8=3;"?AG;*!#(-9AC9A:(;.E/+9%)2'*A(5#:&F-F9,@8*&;.!@#&(@H$##CD>(&4
@r6118
GCCTATGCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGGGGTGTCNGGCGACAGCCT
+
/D1"423@6437/9'=33A0D%F1&B(/*2"@;EC-6?/+&?A0)939AG)':D"A0+75G#!0$.C&AE)@!:'/(50-:>@
@r6119
TGTTAGATATTTATNCCTTGNGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAANAAAGAAA
+
4'<-6+48.2A7*D$E?.F214A2CB6BH64FH74586<;&@49G;<B:0/'(#&:!H")%6D(&7C*G2?29DD#)#F74@+!8:6)D,B?&,H!86+!!03A-'1C1=37$/;4,B%
@r6120
GCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATNACACTGTACTGACCGTACTCCACAT
+
AB$"1"=?GH(#G*1:&1#)-&>:C,>6!+B2BH38*)?/'-8';13580841%72#-0+G
@r6121
AACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCC
+
&4AB:&*?8D=G$%F53<0G680/EB5.9D3900!<F!4/2&)(<3B-F79"=$5DF>5$D1'=6!4G$:"@);*B4"/=H,;8$@!:"95E.E@;5CE3.9"&?;:F#:='2,1$&(C#+!+D493'#3F31);B!<&+:$-:D!A%6D:)0?>!3FB222/,H79A;698$>G%!622?GH
@r6122
TGGAGCGACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATATTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGC
+
;+><$&E*(BH27H!7E%1D4G+%')!.":40=F6"*"?-F?F>!>7?8B$7-3>E$>A33*DF$H#9C*)='7>DD1!<;8(F,ED5CG"/%$.AA@.-./3C%(-&02-@E+G4*!##@A+3'?1@EG1)>?4!/.%=!>*59G#?+35C3D#HA=;H;.+&@7=4&AD?%@H@+@
@r6123
CGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTG
+
/(>/5%>-C(0#%1("A+%.6DCCD-8)H:(+))#G42D9:"E45))4;7./?H<<>A1'F08"3B;262.E
@r6124
TGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAA
+
<7:F62FD'+:-#*>+7.B!"E@388HE"3"9/#2(7.C(B<G4H!8@H<>?#)CF5$2;*HHDF.""9/E+9@>C1G
@r6125
TGTTTNCATGGAGACACGACACCGGATCTGNACAACATTGATAACGCCCAATCTTTTTGCTCAGACTCTAACTCATTGATACNCATTTATAAACTCCTTGCAATGTATGTCGTTTCAGCTAAACGGTATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCT
+
'*)$$+&'$&+#!'$!%!!(&()'+#&&!)&+%('&+$"!#%'*%!%*%!''(%%')"+''*%)+$%"(+!!''(+%'$($"""'$$')&)+&)&(%+'!!"%#"$*++"+#''$#%**&)''(*!"&("+&('$'!$!$#"!!!(&(!*$!+)))#(%!+)%")&##')%!&'$''!#'#'+'"#*(#**')#'+(#&"!"!)%'&'!&%($!($#!&)$+%#+*#%&!$$")(&$$')$("("()""##*#$+'")&#'"
@r6126
GNGGATGATATTGAACAGGAAGGCTCTCCGACATTCCTGGGTGACAAGCGTATNGAAGGCTCGGTCTGGCCAAAGTCCATCCGTGGCTCCACGCCAAAAGTGAGAGGCACCTGTCA
+
(&!%#)+#%$)%&#&"%+&#)$&&"!**&%$'%%%(%+((!&(+%"')&&*"')+*')**$"()!((("&%!%$!'$""(+*"$$)+'!(+&!+#!+)*!'(*)'"+'%')!)%!"
@r6127
TTATTACAAATTAAAGTATGTTAAACATTGGTATAAAAAAG
+
?H42H6BH9#4,@80&-'$G0;*%@;$**0*'$;-7.4E&1
@r6128
ACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGNAGCGTGAGTATTACGAAGGTGTCATCCCNGATGGGAGTAAGCGTATTGCTAAACTGGAAAGNAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTT
+
")'+)"$#"()'"+)("&(')%$$)#&%+(&"#(&'&*$"%'#+(')*+'$($#(""#"&*%!(+"'+('&"'#+!"&+"+$'%(#("'$%%!*%'&((%(+"+++)++'&%'$'!$&)*&&*'&((*)#'$&)*$*$%))"%&'+#+!+&+(&*)#(*!%%'$+!'(%#$"*!("&'%!****"#!&!)%+()&"%('&+)!+%$
@r6129
AGTNCGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCATGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTC
+
:'B1<B$?4/,$$)9B#.7D(/E0$87?&8;H)8#";*!D*).;A;=97@C))FG4D'*>/B'GE'3:!;$/0'6%>B0#!GDG3E2FD7"D0:#%$4!+GF>=G$60-&&-8
@r6130
TCTNTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTNNTGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAA
+
)'#$40=CD("<5.(07:4!@C$>.5?118+-0,G170E?6*)G*';?'D3HF'7!CB5$,B/>"GDEE!38=+HAF))$:.&B?)3(=-49A?8"-E(.5#G.B'=;!0<2(9&6F:G27E$*HG$C$GDBB;GD8E$!G/",:#;*G!.%40421E*BC6**#A/%?@44&*$;>C&.,+,;:
@r6131
GCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAATGCCAGGTCATCTGAAATAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCNGCGGCGGGGAGTGC
+
>1:=<0G)!<B+25(2;-B7"GC!""2$G(<"5A)#,8,@..;4B.A"!DA+<F#H!@+1"@<+/-:C$!-&D<:C(87D9(@3;4>6:>5=6?DA75()4/"41(,5?4#,(A>'"81$?=49.4?:#&?"3;(?(?(H475AB1=@.$>$)@:2=B;;9(3.FA1(1;%2%5,30B(=7B8(9%@0=%.'85&E0
@r6132
CCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGAGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGC
+
93$1;CH#9B>"8,117;.F#*FG5'>"7>F/9:+-92,2*.H782><0%6BF;(2;&B64/5-$(4;E&'$:C;G;A?9/AE$4!'45&8!9?F,/91E+""
@r6133
CAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTNCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGCCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCNCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCAAGCGTTNTCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATTATTATTACTTTTATATCCGCAGTGTGAACACCGTTGGCAAATCGGCATTCGTGGAG
+
G:>G1+;+.+H?-C6&:G%$<H<+;8+/49&-15DG4821?66)B(*>:<:86B?(;F#.92!*6;-..7#<C(!4-=,??:@G&#+3/'=5-<=B*)<5A*.)FG6"@-!6HBH%-$F.F653(C'@3)6>8CGH.B*>(!.49%A05""!D5)$>2H#4=2F)68?%&5@F=(%4-"2@,4;5'.8'1214;=;H=D2D4!>4+.+F>)=#D2CE.0#D)D,382$&7#*16>G;@.@!&!H%"**@4823<A299A,$A#237"#4?%'9&".70A=?B9H##6B;:F+!:8@'C<?)H3BE$/78;7#@-B,3,&.%AC4(":>EBEB<-$5=/8F>E6F>G6=:-1=(H#*E+@$8)10B4DCF"8#1*(**C5&:5C4<9.%,;,4.<+,;=76'*=45D3G@BC8+0:B;8E>+73/A<!@)#22/4G,?$,1C.$A$)C9D5"2>?(F=?;5%E;(2#-*F(8A5/,@$D4-*EG!FBB0%G53%'>".+!((/<2C8?0=H?%CF$B>#
@r6134
GCTCACTAAACATAGCAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATANATTCATATAAAAAAC
+
%7&C=29$73'%0)14D#9%>&"*(:0C'7,.:$A?0%$1?'3@.@$)+23C7@"6">#-<:>5&?6!<E(:)'):??
@r6135
AACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTG
+
=1C)!!;<5!D5*&%0.1$$E$,"?>9=.,#F$69D0)D:5F->=E*DH<D50.@'F0!7>='&,/8:;4(<%0>1('5)8,H'&)9#$1B+/,E>84='C@C&)%?D5*BD4>?=02(F3G-(=H:;=8(G!=$-F*CD4&(0.2>$';57D.#4/2&0D5.B)/;.FB%154C3?48(%'<4/#4F.0H$B)-GD>BG.3CA$.35$>=5?/B<AD2E*"!=C=%#88B)4AG
@r6136
GACACTCCCGCAGAGAAGTTCCCCGTCAGGGCTGTGGACNTAGTTAATCCGGNAATACAATGACGATTCATCGCACCTGACATACATTAATAAAT
+
'+$$")#(+&'#!!#(!#!(+(()&*%("$%%)$#'$&'$%+%(*%+#$$$"&%"!%$)&'$*#'%)'#)()"*%)'%%$'$&&)&!!&$)"'*&
@r6137
TTAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAACCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAANGCCT
+
B@$6-()8<'5'%D")H'9@)*";906279'>1A*>>B.E'0:#)"-"G/<3>-,>'(D/,13=#?H&3.--4;?4F%"$>:0(<2(*A,<2<750G-,;GE8=E*%(/;&.8,9&D?7"C'>.0A!,G5F-3:D!/9B3$8:/.B
@r6138
NNNCCCTCTGCCCNTTACCTNAANNACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAG
+
$$#!')%*&$')("%)**&!%))#"'&++)&)%%&$)&(#$&#&&)!(&'+$+#"#)+"(!)"&"%("&%+*
@r6139
TGCNGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAGTTAATCCCGAGAGTCAGCGATGTTCCTGAAAACCGAATCAN
+
F/1-5=F*%!2%GHE@HB,>(6%5#C:*7%"1(1,@"?;//D("&0&*0:"B3?3B;"?B"'&=3.9:!?2=+/6H<*'0?%FH/3D>'FD"21@BC13%$7>D&85?7:4,'ACF1320FE9=38:6(4A@;BA0BB6G*E2%3##9$6A:/#?"H.83'72<(#0&B'9/B51;,9.4@*45%8A8F8G
@r6140
NTANGGNTGACAGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGTCTGTCATGGGCTGTTAATCATTACCGTN
+
(%*!$)++")"&*%*%&'%*"'"*($()'&'%(++)!*"*$%#+"'%*$*&%)"!%))('&%('*(&!$+'!!($&%+$#$++!+)#''((+)&!(**&$#'$#$*!$%"!!*%$)(%&#%%%(*&(+*'*"*$!'((!(&'++'$
@r6141
CCAAATGATTGAACAAATTAACATCNCTCTTGAGCAAAAAGNGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGA
+
-;6+#GDEC:70)!&!!*H0%&+87*0"H56*.3G26C2:2F#215G#+1@6-#HFCB:/5H?@42>*=F(34.(9("<)H/%9%E0H
@r6142
CATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTCAGGCCGGGTTATACTTGTTCTCTGGTCAAATTATATAGTTGGAAAAAAAGGATGCATATATGTATGAACGATGCAGAGGCAATGCCGATGTCGATAGTGGGCATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGNAAAACAAAGCTCCAAGCTCAACAAAACNAAGGGCATANACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGANTGCAAT
+
+'6D1=5/#?!,&#0,!-1+*#FA':9A<H+?>,6.!A!/C;?"-G:<#?"E$H!*H1/B)AE"==B,5!,,F(2@H'/>E,:1.6&:AH<<>4D<,7,D4&AF;&&4;&7;27D&9#E6G&#B;1@>?D7-04H72*'464C8-09@0F,3DC)#)8*:"+?@=H9*559C=$E-3!4"0'5#HF".)-<37>6?DB35G%A4H$HA8<7&B8)111,"'/C('1$.#$*H2@6D">(8<8$:(:6B.H@#;'G?@4<&>F;HCH#127A/=>@$8;+D"),2D)/(C<+&3G!1/6)<<@6G-5=>E@GA68C:88%<<-*)#GA68
@r6143
GTTGAGCAAACTTNTCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGTGANAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGATGCTTTTCGTGCGC
+
7=1EF)E=/71)9H!H)(!4/;)$.5*G#?=/'8G?D:5GFE5H%,93G@&,EH?F6;4,FH=?/57;=F)&8E596?C8?/!<2(=D.A1<>9!DBA)/+E8*##9HDA<38G
@r6144
TGTTTTTAATGAGGTCATCACGGGATCCCATGTGCGTGAAGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTATTCAGAAAATGATTATCAAGCCCTGTATCAGGACATGGTACG
+
%8H1&77>!&>*@11,&30"9H)):=")9BA7<)=D?.58/*@F0F#3'+%>,.AA:&(@16GEAF9!(3<9%8;,341;&)+E@$.0"08G?G:;99*F0?'/:5/$&E5-2!)4):;85'5<>:E/&4&4F=C!EEC'#)#2*>H)3)8!,
@r6145
CGCAGCGCCGGTCNGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTAT
+
3%2")%*B7:,6#G5H8(,;+&.3&.0(D)+;<B"B,%)5*A8D'"!#H+4AD'1$/E:D2D!75."AAB80B/$('-*F.08):<51F?0/2)@':'GF4;B!14E"%'78G::5>-?68$GH-%32"?22#=0*'6+0G<GA*67=4F=BHD
@r6146
CGGCCCCAAGGTATTCAAGAACNTCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTNAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGC
+
4)/H@8>>$?%5*F,=A&,9A&,<,#H38FB7"1>,!C3F(28BF@.-?<(1CGC59;D6<=!D9*@&='*%(B%&3'$F=3:,8..;:*C;#.A3'4>B5+*>>##)3BC.?83!1E%+/)<?8%#"9/61,,*1";7
@r6147
TGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTCCAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCT
+
D@FH*:?.)4-?2<DHHA,8F>0?5681*H#B<.$E0<&CF2>-G/:G-E=CF8%69@D<D/6>>-AD",G(D!"(/">=-<$14&"4)3(/.AE;9$6-77,;(1"4B%;B)G$>,#4!'$=DB+F4#:A%-/>(<."6,:11F##D.6>?.+7B</"H*3!$E)-%%(<@/G?G%3H)&/836+GE;<2A9EB;653B56E=?4(A.5>B&C.E+!A0)9E
@r6148
AGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACGTCAGCAAAACGCTTTTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAAC
+
8&?1,B+#C,<>!7&9&+,AC>)#7;*GCG0F$>(HH;!A>.223G38)'1"AE'34=6G'#=%"&'65=)3/(4,248H;?394.-05B?A>,6%/9G13BE4">;7%&33C!$<.::
@r6149
TTNATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTT
+
;,F!=?.B;@80)<;.>--:'F%AE1F0'=?'3H%%'@F?<C)#3$B%
@r6150
CCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGT
+
+E8G161A<'/2/*;/9E+@,A75D8%5B"<#;<!8+$3D1"26?/%*"G"F3B4A>B)&?C>4)-4C<>18/,5,81+@'68567@A5?7F.+@HB>5'".F+H=*9&(
@r6151
TGNGCTTTGNTAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCA
+
&'$%)*&)%#$+&"%)+%##$'"*+!**($#'(#+"%!')*%*%$!$&')#!&""$&!)
@r6152
ACAGTAAACGTCTGTTGAGCACATCGTGTAATAAGCAGGGCCAG
+
+*!*"*#")+'$!**!!+"$(&!%)'#"%*!"(+#'*$%+(#$+
@r6153
GGNAATCTGGAACCGCGAACGAATCAACAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATTTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAATTTCATTCGGCAAAAAGCCCGATGAT
+
D;@/&/:45GGH%17&(=3E6E+1%@:BA$@$1H9G87!B=.<>+B++?(,#<=!1+49%"D5,6?E!H@73""?83-'"8$B-FH9E)1=!25DE5*4B<*(,!8873D/G-/3B"293B+1A:D'?5>:2'0#%E"!%!D+-3.+:65.E",,C9.0@0C3B8=!3--?E+2F<C#@4!@=)/>9AAD&(&?5F$!23'FC./><<F9&G#,FG04%4D29.>BG418(5&H.%F.(;D)
@r6154
NCGTAGNAGATACGGGATATCGACATTTCTGCACCATTCCGGCNGGTATAGGTTTTATTGATGGCCTCATCCACAC
+
&'%$*$&+#+'+**%(!")!""%$$&)'%)##&"#+$+"$&)'&&+#)(%"'+&#"#'*'!$+$&(%%!'&#*#"'
@r6155
TCCCGGCATTCATCGTTTTTACTTCGTCTTCGCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCC
+
$3#7<2<DE';G:E;;,@+#C:?41+3085-0*A0()GD74(3A538.(@F:?/#G:G?;9/*=<:84H.$>)+:B8<<:0/6"5*5GC%B+#;'-*1A1?HCAG,4:5,C8,(?5!HF-@.7@
@r6156
NGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGA
+
!<*HGG93*+@F7''/DGB!?.F;;E142G(");C@+0&14CF0/7!6-<4E$*G9(:7:@
@r6157
GAGATTACGCAGCTCTGCTGTGACTCTTCTCCTCCTCTGTT
+
,8+4'<34E;E'12>8&2D$F@@/.@.41F*E116"9$D*=
@r6158
TTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGA
+
+!"+&'+"#$)'"+%!$*+!++#$%+&%)#!*&!)'%*"$$'&("!+%*')!!($'#&""+&($(**#&(("!*%#&%'
@r6159
TNACCTTTTTGNNCAGGTCACCNTTATCTGCCGCCACTCATAAGGCGGCGTCCACAGAAAGGATTTCC
+
#&*%)!$()()#)+&*$$&)&*%*)*!$!''$&$%('+&%%+$'&%%%!!$)%(+)#'!$)*+&*)#'
@r6160
TAGCCAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTGTCCCCATCTCGCT
+
96#H!"F4+=H;86%%475<,7<'.,C!/$#4=D)B:!'$&1%5*##8&H81;9BE%B%'C4C==")64'*);787$@D#H
@r6161
NCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATGCCATCAG
+
"7+?<8+E""6A7%3D-4<(8"<73B/?1.0A#3E/F6C<:@A,G64A%$*,'#2'$%:F0B@;@
@r6162
CACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGAAAGTAAGGGTACCTGACGGCCAGTCCACACTGCTTTCNCGC
+
B272!1A22:*=/+2)=0<///F86!@%-3%7%H4:.;3,4@>#4G5()A(89E;0B8'6&4-,@CC3/9F8%+%*E7=;4(*":
@r6163
NNGCNTNNNNCCNNNNGNGANAGANANGNNNGTANCANNNGANTNNNTCNACGNNNAGGGGGGNANCANNTNNGANNCNNCTCNTGACANNNCGNT
+
!##!""!#$"!"#$"$""#"!"#$!$!!$!!#$"$$!!!!#$"!""#$#!!$""$"!"$##$""!#$""#$!"$#!#$"!!"#!$###!!!""##"
@r6164
GGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTNTCAGGGT
+
F"0#>8B>,%GB/,3%2*@)22/A1<D?A>%;D"!E%<G:)+"*#'FH26#!2C?E'3C@35H<08'#338#06*@*0A+?28,
@r6165
TTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTANCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCA
+
41+70F8)2)>9!:#7,37#0F8F&3A++C!C&!'8486-<8040.+@-"@&5#28'C:'C$:#(@&07,=0"6,)A$E1(/HD88>->A2.@,2#!;"*EF%+"!'>255'2$A2ED8D:?8#>7/D@*07.4=@&&11"H00B;F/H9+".04,8C%-C)00&=<:><4&HF#)BA/G4>E4'A9$$%./+38F8H?,8G>5?890&
@r6166
CCTCCCGGGATTTCATGAAGTTCCGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATG
+
*.168H93@?,?HG#'/=:%5?G1%2'C;EH#B!,:G0D&H0B66@E3'0"3:<;30(6,?!
@r6167
CGTAATTCCGGGAAAGCTGCTCATACGANACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACG
+
->-7F4*8B!$1-GC7E1D"*#63)-*D=6C!(."B:&@,=9%H&*A53H<>.?>>?F--C6:8A?E81A!:C&''#
@r6168
GAACACATCGACCGTGCCGTTCGGGAAGCNGATTTTATAGGCACGAGTATCGCCTTCATTAA
+
9$.H'''#/>F8>1%77G#>3;%(,&?))7%:*$07,D3<"DFD=4/.2G>H$$5"*>#".*
@r6169
AATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGANCATAAGGTGTCTCTGGAAGCATTCAGAGC
+
*H!;:%$DE9&785.!?7"891+.=E>07D"92=;1!'<*A":?;1/-!50H=5?6B)>CD573>:6HE2$F*:.1&$9>"?B9".G&)
@r6170
GGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCT
+
980HF=(1,!ACF0<9-4%<?BF<D1%.2--2$FH!+9A>,>/G#
@r6171
NNGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCTTTGCTGGAAGCCTGGAAGAAGT
+
##<?0,+,&"'D$)/4&,#D,"9<!00!(%=8>B*04*29<?3)3/':HC@D,&%!GB<6/@'19D-(B?,4;?8)B,!D#6;H(D"21>2$<.G5.
@r6172
ATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAANTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGNCGACGGATGGTGATGCCGAGAACTTTATGAAAACCNACGTTGA
+
4:28"!$8%06"&*H=D'#>1;50EE%(&/9,++'A#"A+(*462$'(9*.9,AA/;,!4G<:=&<F@A53H7/7%""&08;D/GBA=5-G+@>5456=AB*$E?2?:%D$-?2A/'$D!D22?/+91+:D<0.=A32B&-3H*E=H1BB=00/H%/$0H5;<A=2/>%!;>!$AB?9<B&$
@r6173
TGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCNGTACAAAAGCGGTGTTCGCAATC
+
+"$("'+*"$('(%)'&($*''%(")((&*")"#!+*'#)+(*)""!"(!#%)*)*(("&**$*'*)%$#'!"&#$)+)"#&(%*#!%$#"*%"%($!#++#)#"")%+
@r6174
AGCANGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCG
+
'9262004=*:2C$53=*1G+BA"%92%:9H8E;0"<FEE6)EC&9%.AF;E4/;E$E&$%6(=$?(@4H==C%&"2'<=?3.046C%H?=>"E=9/$)-().E()5&9:/*8+:!%>%<8'B4H4++"(@;?@"'.;:%>7939$8B?)$EA!$G5;=
@r6175
CATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCAT
+
%E7E9'3"$0D>"7(,-&#-:.#/>28235$DE?=5$1+&0%5G==/;A
@r6176
CCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACNAACGCATCATCAAGTGCCGGTCGTGCAGCTT
+
5>>,*)(#137!=EE1>F)))$!)A#><5D$B?-(<#;#.==B4<'=EC5=-%9-%$7G@2'4</*-7@*!92EE&,6@6*@&19*&
@r6177
ACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCACTTTCGGAAGANGTTCACGCCGTATCCGCTCNATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGNCATC
+
D&C*40>H?A/0)*:AD8:;!3-'BG+G%-GCD.3#>-!'&/2GG;.4E/)6?>-&E9!B.,/"@;$B$#C:;H&3,'?#C,29'57!=00/8A)3.B>209C9<7F?$
@r6178
GGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAA
+
GB897G4A-:5+':,G<.$:.99H%0+3G@,?E+!$-!G%-BB*!E92"1<.>+1FB>/60H,,?#4;9&>@03+%$'#4%0@*=A+@GB?D-<GB2$+:'.<!-(H01A@/3)#%F*61*-)/%AH@<3**@12.=C><,#)1-<D</#.5)#H*=F$1'6#(<,60?G)B6.BG%
@r6179
TCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATTGATAC
+
AB**34&'0E:(:";74,H>=*#HA25>8B-@>6==$,=&-F,#$5A19*@
@r6180
CTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCT
+
C<?!!F234?3)'23B.3!:E*"**.>;$74F/+C5F>="8%'%G87*'$-/"+,:D9&E10H=(%75//'9,!
@r6181
ACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTATTTCCCGCTGCC
+
5@85(08'3G:/&A56/"D)!!,7(,84<?+=%=G34B/+$@>E80<(@>26-:=C
@r6182
TCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCT
+
-F6);-4C@'/D:G3D@+H5>/)<E$@7@$2<31#G-;D)
@r6183
GTGGGACAGCAAAAAGCGACTCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCG
+
@7*/9?8"#2*D+534E%*'6"C7-9E$&-056$2C%9'G3E;.*C'0</'E,">F"<8<2
@r6184
TANNNGTGAGAACGAGGNNCNNCCGGATGTCATCACCGCCGTGCA
+
$'#&"&*'$#"#)*'#)""$#)#&)!+**$*&('''*((+$'"++
@r6185
CACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGT
+
669B+589E;#)2214H%(8;/>,G=B6G55%+182:$G"HE/.C+
@r6186
GATNCCNCGNGTCTACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAANGAAGAGTCAATGGCAGNCAACATTTTGACTGCTGTCACACGTTAGCAGCATGATTGCCACGGATGGCAA
+
"')(%""(!"'))!+(&()$(&$''+(!"'!+)$#+"$(&&'&'%%"*$*%*#%&$('&"%*&#*)&*%*%%!"!$)"*%$*)+$$%$'+*+*%*)+*++*+)!!$&(!(*$#'")''(++(+)!*$')##!
@r6187
TAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCTCATCCTGTAATAAGCAGGGCCAGCGCAGTGGCGANTAGCATTTTTTTCATGGTGTTATTCCCGATNCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATNTTGTTAATATTNATTAATGTATNTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTACTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACAC
+
##+*"$""!)#*+!"!$&*"%(+++&)"!*&)&)')%(%((&%(%*+&+!))(#!+$%#)&+*#*))"!($'()(#+%%!+*&$")!#)'+!+')%+('((*)&)$+())$)*'*&**#'*+'&'&%+'$+#$%%!$!))"+'%'&$'(**)!%!$**"%*'(%+##$$(+"+'$!$%'!**')!$("!)++*%&)*!!'(&&&#*+$$""&'**()#++#!("'+"(*#+*'$#$*!)+$+!#(($'&+%*!#!'!(!(*#&!&#*)"(&!#!%+$)"*%''(!)#+"+"&&%!%%''''#($)+!!%&+*"*#%$%#'+%$*$%)$"$&+"*')*#%#$('$"%$+!!'+$)(+(#('++"'#$+'$"(%$"&*)(##((+!!#+"%'+!#!"+&!&+%+$!#*($()**'%&%(#%($"!+&'%#+*")&"**%'+!#%"*)")")'+*+((+)#++!&+&!"(!!$(!#)$)(+&#+#(+*'*#$&"$&!&+"*'%&+*%"&"#)&+#%&(*'%'&
@r6188
TTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGANTTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCAT
+
>=C(+F9E-(*@G*9=B,-&<C*</743-,057?F=;4:"G;!558?:6*A6H<G8DBC*1$B&?8%2%$%!5#7+D*-8'<96+%G+9B)*-#<&C:,/4.GBG3H2*GA0/'<H-E:12*227A667(G4<)A5%#=#
@r6189
TAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAG
+
=?(.>.+3;+<.>@5'?.97>9./>&8(3*9D;->E23@9B/(:0+83?=+'?"#89-><2+/DBF*D?EC8.ED31/%=2.?/$E*%,=#?*B2.%E3=A(."F/35%H4F.)G!3!"1)B&'2A@2<.@"B$93&$
@r6190
GGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAA
+
H1G8$,'G!!!G!04=C'"==DG?!7?-6.=H4;2'G::6"@"2;;B0G=0/;&?F#&9+7@5=C@?.G-@&?F9"")&E7?2(7C'
@r6191
CGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCNTCAGGAAGACAGTGNTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGANGCTGGAGNAGCATGCCG
+
EDDE)19//-B/5H4*?",7?D!$:F56*E(BE!9>$)G(.G)*+F0%")(;*.'<-&(1*96+@*"%#%=1:A!!(:F,B07(@88$36G69(-4E/);F2(">3!3
@r6192
AATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGA
+
,C(-C+#C;)!.B-56&7!(*H(#2*6%$)5$9EA"53*B4>05#/6G3F
@r6193
CGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAANCAGTGG
+
*)03)036A)D&@G+.=/+@5F*,$'56=;>2$5B?%)$5(3$"0/:C/=,!)(/61>G7AG=B88*%=D'?!?!*&*C#3.:@#B32D@(C&A7H/'6*//1.&2
@r6194
CGTTCTGCGAGGCGTTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAANGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTNGAAGAACTGCGGCAGGCCAGCGAGGCANATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCNGGCCGACGCACAGGAACTGAAGAATGC
+
;584:&A=#8"!D8F8?7!;=9/3HF'!'16%.;6?C<41.51B!:B(4F1=B?8E=&1,2AG*+DD1@.1@"B'>E?406=:*8!H:D11:,8E$D93:D*1<@->8BB?C6:>"D>*G(8+.:H7"3D=E$2ED61;!/!%/:1-?,+F/7+7!6D9+=:?9:$.G"-F/)?GH)"C9/88!.#B;!=#7H0"1?'9*@/:C"%2"<@C86@?:.?>7
@r6195
GGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACC
+
:+$)1B>#B!6:*ED).04->31@(.2@#C>&4;+=0?6$H#($<<
@r6196
GGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCATTGAAGGAACGGAACAGCG
+
H5/)(E0F01=(:H:.&&E(<?=/@8*2852A*866%2D</A;+C8B*-(C)=.-#FF3!&&
@r6197
GTNNGGNANAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCAC
+
#&$!*'"&#+*%$$&#"!"+#%)!&($!*$#$$!&+*&'$))!''*$!*(*%$(
@r6198
CTGNNGATAGATCCAGTAATGACCTCAGAACTCCANCNGGATTTGTTCAGAACGNTCGGTTGCCGCCGGGCGTTTTT
+
)&#*+$&&"(+++!"+%"((()!"*$#$!(#)+)#*#&!&*$"&(%!!'!))*#*$#+(+)'%*("&&'!!)&$$!'
@r6199
TATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAAANAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATNAAATCATTATTTGATTTCAATTTTGTCCCANTCCCTGCNTCTGTCATCACGAGACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATC
+
5*#H.49=%'+=G(:@)<=;*D0;%<9EE4("<E3;!EFEGC9;!@'D8-E*C#5?*FC(E>2DB$)5G%4?&;A!);!9.)A</G,$,%E2CG3GG(E0'G0,GG,>B@):."$'293,6!!$DE%B#469H+10E),$/CCDB?0AA/-6#FA%;B#7$%-5!?!-DD)B-AC"FH;:2<B'9>:HH$>D1=!*+1.@?H/E'=:8>D950E3%/&6.>-
@r6200
AATTAGTNACACAGGAAATTTTTAATATTATTATTATCATTCATTATGT
+
:0=!'9:06+5H76.;(4'9,E7CF(%G*AH!AH'/'="1!*:#8;BH%
@r6201
TCGNGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCNCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTA
+
9,1D!C.-6>C;C=HG>&3;>15<"/%'?)/';1DB(/G2E5(FC+3H?--B)@E)7!<B$0)64,,G:FG58F%(8(F/)09(03.8G+<(1&G%!),:.GH40&-CE53-)349BA/?H15G%<&?7EE,74CA#<68A%/D.*C/8/B!;'*&)B@?FH;%7.,8('9(75)E,B/>,@:8)E838H3":?:$-A<&,G=6'G'%577!1@F,17(057*C/1?D90+$2==E/;7%CD;H6#A*829;0%>A6>))
@r6202
GCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATNGGGATGGGGGCCGGGTGA
+
0'33+5B3(9:C2->GG%"?E$/"'*B/AEEA%7$!7A3C/.G16$$>CC/#6@87+"8B:G
@r6203
ACTGCCGCAGAAACTCTNCCAGGTCACCTGTGCAGTGCTT
+
GCB(B=8D)-=>/H*/H5!+77GH@4A2DF,BBC%!)E->
@r6204
CACNGNTNTATGCAGCATTTGAGNAAGTGCGATAAATCTTTAAGTCTTCTTTCCCANGGTTTTTTAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGATTCTTATCAGAAACC
+
!'"$($"!%%$)))+&*"*!"#+$)"+*$($&%''++$+++!#!*&*+"+$$(#&*(($*&#'%&())")'%'$#*%'#%+&+%%'+$!+*(#*+&*%()'"+!*!*((*+%&*&#''*%'*&+*$$&*#%#&#(&)$)%#')&$'&)!+()%&'"$!&%'&!!)##&()*"&$%("*!++"++%%+'$(%))#*)
@r6205
TGCGGTNTNTCGCTGCCGGGCTGGGTGTCTCGTANGAGCAGCTTTCCCGGAATTACGCCCCGATGAGCTACNCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCGGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTT
+
38>50$G%=!CD*E7BC%6B"59-G+BD#@2+H3$$9;H*:;F6269#.>6EB=#5,,.35=2+BB$48&));A<"15:=E=D62;()0=H).4@3G.?D.G'7(==A'@7#&A*(=?(CFDE*$&8-2?,1//897EA$@$,,@9$,F#B)5@26F#CB3(1(F1(.2$E6*-%"E$F>39F:+!B+(C?;#<$$">)B7+/=*DF+:8-%2#<D1=52+2++FH,;+D
@r6206
TTCTCNCCNGACACNTATAAANNCGCCNTCNCANNNGAGNNCAAAGAAGATTTCCAATAAGCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTNTATTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCAATATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATNATTGCCGGCGTTNGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATAT
+
%'$($#&("%#)"&#'*&("%*&%(*###%$((%%)&'"!#$+*%($(#")))%#(*&()$$"'+))!"#"'&'%!*&"#$('$)"%+&+'#$(#"%#'!"%#!("!&&($&"++**&*&%*')%%#')!""*&#*'##)#*!$"!*&('#")!+#+"&'&)#!*)((+#)&($+*!+%()!"(&%*"*#)'!'$)+%&"*)$$&++"*%#)"'!''"'&(%+$&'))((#%'$!"$&((%"%)*$''$(%)'#'!%+*#%+"+&)#*#+(+*'&"$#&''$!$("*%**%"')'%%
@r6207
TGNNTCTATCNANATNTACCCTTATGACAAATATAGCAAAAATACTCAACTTC
+
'(!!$$"(#(!'#)!$"#!$"+)%*&'###+#$)%&'*)#&"((#$#$)(&((
@r6208
ATTCAGGGGGGCGGTTTTGAACTGAATGGCAAAGGCAGCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTT
+
&1G(%5?F=3&&*95AA24$1#.'FH,>E"6G42:31.<)1.7DF;H.)+=.@F9C?=E-!%./8):6+E:,>..5.&>2/D45G@66!4*8$!'&((/->A>C*8F3../1,7.)>+88"EBD##+-G-'$%;$6C:17CC6"(%)474&$/7
@r6209
TTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACG
+
42,58-#=?&H!#(",,F-"3,75,!9FE)C2/?#0!%/E@F9?F%7=577<12<9A>GE<!8+D8B":2,+/&$$C0>#H"83C5.!H65"2,BHF5>:-+DCH5('2;570%D%/)%@D#E14=B'&'/"+H*:<:.B+1>=6H*350GE<17AC:&*H"1;)DBDH&E5
@r6210
TTCTGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAA
+
G%,@#3*&A?;2$8@*C9"9.#,B#5$1#1:&H53*59?3!4A38:*967>)(7=92C23;.#AF((=-B,8D*.
@r6211
GTNTNGNGNGNGNNATGNTNCNCTTATTTCATCTTANATTGAAGAAAATGACATTGAGTTTATTNCAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGANATTACCTTCATATTTAACTGAATCATCTATTATTAAATCAGAAAGACGATGGGTCGCGAATACGCTANAAGATTACGAATTATTACATGCCTTAGC
+
#'#&%)"(%'"#!''%$!'"*"%'&++%'%)*+$%%(&+%#"""'($*()(#*))+!#+%$!!&")#*)!'*""%'#*&%%)&('&$"'"!%&)"$#%$&'*$#)+"%('*!)#!"*"#+%&*%'&#*(&)#'))+!"#%($"%##$**'#+!"#$))%)#%%+&"!!$))(%*!%)++$#*((%%&!)#%&$*'#(!$$'%&%*$'$%&'"#!$'&!%
@r6212
CTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCG
+
B%!%4-F"G'$=FA*?/34653@$B"&$=2A(H(!/3;);%06$D==&;&A1G#?)>G@<G2;7GB1#'AF&>$',*B0&'1$/0-
@r6213
CCCCTAAAACGAGGGATAAAACATNCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAA
+
>-)G1"+6@D">%F276+36'=?@)C1B#G/E>:*46-*%H,.F2!&771C4.H;1;!F""17D$@@E%)>62,-%-1HC+BA%58.B1.C+A55+
@r6214
CTGACTGACCGGCAGGCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGAC
+
A53/'G6F0@-8"!))6/F?=*/-+F*0'=!$-;#8B025153+69+>,9#H5/16AB@7#=',4=".4=<9F!CGB1=F@B"1'.8FD42.*#'20H(!66<A-5*
@r6215
GAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGNTGCTGAAAACAGCGTATGGGAGCTGAAGCTGNCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCAAGTATGCCATCANCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCA
+
(-E(.C(!9<=0C0CD(;2@>)5128%&;79(1!/G8!-:11?;G085H>871B"?)#DG5<)#-"C0B2+0)"F/:D>%#<@5&0,@&*!7:"BB!G%<'5;'))!078.0D0*G4:E)C*0('-*?06HH,>$.0''B"$10G7'C'8+HGA)@&36-D@;+/8*<68+4ADF!%49#9,=+=3>69$H;7!0'=EAC"8!!'-42@6'HD<"G<FF?D'?744,9!D397),':&*A+F!F6$*-F35CF-.A*DD$?:42.,+&#?A,@+%H6<)'9;.:C5C(68>
@r6216
ATTCTTGCTCAATTGTTATCAGCTATGCGCCGACCANAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACANCGGAACAACTCTCATTGCATGGGATCATTGGGTACTGTGG
+
8A"+A<>H+*C@EC3>5:<+8+14,$EE+9+8<2"856!"3!0,>3GE%@"4B"4A9%5>C(D<5)$,$A?":)0!4G2C-A.(7(%291=-'-@46$&10D+BDE!)>FH7A2><=!G<D1:*:$4(8#A>'5..5!C4
@r6217
ATTAAAGCAATAAGGAGGGGTCTCCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAACGCCATATAACAACAAACCATGTCGCTGCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATNAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATC
+
.(2C+H+'>,DD=9A@>?@+(+.&:-6H/*E>=!(7"!,2'5<F&;C"=?G"/HA&!<"+*A$)A8GG7/!(=!C*-<6-2?G'1A$+8115A&89@@@=6)9@5(:-G43B3<)H8B="-).59H3C"+)-.'F4;=0A36E(?D@8:16E0E5B'=#;$3E%3A#+98%G,$>#&HA!7G-%29?-0B)C/'F2@8.C!!7A/;;!4:5H5+DA=H/<#671&=D0'#<#0D::A&'G/&A0E=&@?385#<0B!DBD4<3+&+3*<7B:
@r6218
GGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAANGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGACGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAAT
+
9G/)5C=--D:/2D@F20$"0"E7;>4;':C#;:.);<E=3F0?,6G!0.%1'860F;;/6$=B,13.;,3$!<5?0AE?3&!*C(9):;B:,+5@&#GG967GCFH"9C8$2(;)-E0&37D;";4B-/?#/;'A9!53025G%!>!$,.+%:?C:&*D3B0>3@81&H((5&*(4;"?8.G#-4
@r6219
NTTTAACCGCTAGATGAAGAGCAAGCGCATGGAGCGCCAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCNTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGT
+
$+%'"$(*'$%)'#(&"%$$&""&(#$#&%%()""($!'&(+*'+)*!!&+%"'#'#+#)"))''&&'&"#$+'*&#*&#*%'*+!!'+'#&!*%!!&++!&$&!$!**('('"#!#+%+'!&)!(#"(""#%'$("'$+%!)'+#!#*
@r6220
TACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGCNGGTCCCGGCGTG
+
<+4A7&E4-)9;5C$(0)/28H:H$))3)/@4#4H;'3D(FD%099'F!37;14D26.!$=<99>B81'B'&ED(!(&H.H@H3=+-E5&H@3?8BH(2<7++!B>7,H=/;'E*E1**0@B7'-:+)!"-2,"G!<7B#D6.;0?(0@B111G:"F90F
@r6221
AACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGAT
+
DA@.,CD.&>@:A+<E$):"$H15&4$66A>(HB?EE2/9?)9(3'B2/
@r6222
GTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATT
+
B<*02%B<45);&08>'3:;H,1"-F+C('#;,6,A,198@:6!G;5:>!67G-C(C2*50%,EG)&470
@r6223
GTATCGATAACGGTAATTCTTATTCCTTCGCTACTATCCATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACAACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGANATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGC
+
$%C7"861BB:!#D*!0;3A$.!A!=A/$4C/0)=0?*30="*<42?820!:?/-'!>GH3)"+!69E#:!&65"B<:.E1G34.,2A.1*D'"C9@*)BB7%.:>-0HG202()A*+@4%49"385E4$!H1A$#"!>@=&$866F).;1D)$5H(CH/$$#3?B:G.FD66G3=.D1)B:9H=EFE@E/6EFC%1.(BB+.1:"1('"@0*2D3A(-%9$+3>4'85(<$0./"&/0BC=B:9<(GC76=?:A87AB@78,E8G,&.90)%;<9H?8:9.9A=))"/;=8.1,(4$6-(2,6-=;-BE"*;$'<A?2?=*0'.==$=5&082$<+&7C@;B;/3$=8"='%."
@r6224
CGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTTTATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAAT
+
.+D5947F)>)2*D+23;99)&30+>#G"DB,8'#$)C8"72/!%H)FB$%FG><G*%1-!#A3.CF9-&"(.)9#>><6H&#!=&=4$!D)B7>AA6%7?CE2"3.9';+G+?.C;9&,7
@r6225
CAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGNGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGG
+
.;<0:5(F5?,$#*3F3-*<&-.E:@57H6D%5;?G83@7="5A@&5,8"5)7>0?=G!"!>B&<-E$,6?5'4*G>10:3&B3'1($=$'614E'/*A%58#-D@>:7>116+<6((2F*?C04+/:6C;45!7!.-'7-$%?CCB-EG==//<,<<)A9C9!3D,;,:)FC>27A6/+DHG#959(@47&34<3=!F-7/;60(#/H4C#H6G%C#"+>&5<B-)7489&<%22C!,1<;A?GCC=0;-#*%=%>C
@r6226
AAATCAGCCAGCAGCGCCGGGATTTGTNGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAANGT
+
?E.C9H'@=')EAH0$@>G>85D7F:"*!E2=)(A8!+*E(>;D%9"B%FD.<?)A&@4//7'#/>-!5E('/:
@r6227
ACAACGGGCAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTCCGAGGGTGATCGGAGTANTCAGTAAATAGCTCTCCG
+
+086/%9-8505H1BF46',AE&3<9&/:>>CG8>*D60:45/F/G<(%GHF%@7'&@"81);&&'35G?=2B"27'%@>=%9.:@8'26&B&65<-'8"#4BAFE
@r6228
TNCGGGATGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGNAACCACGAACTCAGCCAGANCGACAAACAAA
+
##%%"+!'#"%+$*#"))"#)+((%)*+(%""#*)(+%+#$#'!))"&#(#!+#&")##)$*))*#*#%%$++''*+)#$%!&$*+)'!&&+'#+)'
@r6229
GAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGT
+
=)2-.39?1G0?5:<F27FF1D6+2"3HHAB+A>,!>FF3$./
@r6230
NAGCNACCTCATGTCAACGAAGNACAGAACNCGCAGAACAACAACCCGCAACATCCGCTTTCTTAACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCATTGAAGCCTGCCGTCGGAGACTAACGTCAGAAAANAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGATGCNGTTTTACCACTTTCCTGANAGT
+
$$)&))#+&(*""%$'%%!+$((*!#)#%$&#)#)!#&(+#%$*(())')&'"#%&%*'*#*)!&*""*#'#'$#$'$+&#%))%+#((%'&'*&'&$&"$#&$%!&"+'"+%!$#)+#*#!)%+)*&#%&$&*'#$*)*$"'!#'!$"'*)+!###+()#%!)*)***'*#*+#!'()#''%"&%(!&%'#"#+**'%"+*"'#'#+*'+!$)#*!(%'%+'!#)$"(!*(+!"$##'"&'*#")#%*%+!))%*()$)%*)")))%)$+#*!)+**%!&*(%&((+++"(!!)*"+$*""((&$!
@r6231
GGTTCATCGAATAAAATTAATGACTTTTCGCCAACGACCTCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTGGNTATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTTCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAA
+
)7>4CDEG/.;?A&5"1:);=;01A=1(@E;<9-1#<:8C3F@,%<D+<D+/1%0,B;+@*',4%-,726.GF';@%7E<4@'D+H%+.5'5()H!,>)-/5-G%'#C="F?)=(4-%/-B@F&7F0(:6G*@,A:H<931/?74><=AFEB("+"8.<.2$A6?:-,-A9>7%!<"@'$AH?!+*<.B$)=1D3-#)7"$F;A,.7B9.0F1.(/A369*3)?9/0B8ACBB6/,6(-87"<H:A6$G&')8H2F%;,4%58(5;F>,=,6-#'H!()7H8-!A''&"1(-.)99'%A
@r6232
GCGACGCTGGCATTATCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTATCAGCTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAANGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGNCATTCTGCTCGATATGGACACGCCCGGCG
+
$;H,/'E%2+&$4A0.-=F0<$C>!9%/F?&9E"@6A6:(.8(4&%=>:%1%F7&:>88.-8!?G=68->+&2C;,D!!F)+50>B38(%BB"H-0/:.3D#-8/??G1-&C5!?0D7++D*E52#9&;+D&;1!95B<:#:!"*F'/0:C;#1<30#&&F/&8D?C,<F?(;D,DD&B:/@FE8/%2H&G3+=*#4E)1'?/6%EF;&/DD--A5D02'9#1<9<+3=
@r6233
NGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGAAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATC
+
!'GB4!+C>3C0%;43.09C(9;EH;3E9B';5$/%F=B'<!"45"&9=A3?&B0/>#)G2!&%">/'&5(*/(B2#",D+!0+7=3!!B<(3)6/$)E@(565<<)+FA)>6@*B569BF*!#'E)+-+61>;!);,85?605AAA?5@<<2==;$;*:+304$G,!+F!@"B=@'''13.::79<4@@)E%-/H=%:6H#$&B<8D31&@9H(@:25?!%F47.;#(<F1*G#,,%:F>@A;E2@;=.
@r6234
TCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGA
+
3=D-@;6%D).<05.3+EC7&A7>!82<%@>HDH#><#%$'7<8>:>"&7<6$E!0&'5BH;F>>H<+<4=84:A%8G3+4C8&.E9$=!
@r6235
TGGNCTATNNNNNACNCTNNTANTTTTNAATAAGTNATTCTCCTNGCTTCATAAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGAGCTACAGCAGTTATACATTC
+
&))""$#("!#&('&!))("*#"*((*")+&%*+)$')*&+""'"&!+##+()"##'""+$"#'#(%(*%)&!++&(')!&$(!!'***%&*#$*$)+!(+$(()*+)'!)%)*&#$#$$!)"#+%'&&"+!&+!#)"!*)%&"*
@r6236
AAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATT
+
$#E9$<CB5F103G):(7$H)9>$H#8<F<?G<>#,6()D@B49=%17#G>0';*?94;-&2G$6@G-&F?D9;)6:A95,D@(.<;16:>7?&EA%HF4=2@6/H
@r6237
CTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGNATATCAGTTGCAGTGTGAATGCGAACTCCGGGACTCTCAGTAATG
+
35@!FHF=*)>+0./<=-(-(!E;#3=,7+@.1&(C7)BE9'/44:"4',)H9)6#%"(!2A/EB7%2E'A9:/'>,)%;$0>1EG7%$
@r6238
CNGCNGCNTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTNGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCG
+
$!)##(!&(+)()%$+'$)*($%)'(#&(+%%$&%$#$*&!%(($"(**+$+'$)$#'"*&+)%'"+&+%$'%+&"'"#$+*)(#&#!"&")$
@r6239
NTGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACA
+
!+**'#20."'H,6HDFH;+(1G9!<,4?44F+,(.;22?,@H
@r6240
CATGCAAGCCTCACAATATAGTTACATGCAATGTTTTTGACGGT
+
#"&%;!&,$:H!(7-!4)+;:E#F$1E1$-+!9:5=$8%45E82
@r6241
TGGCGGCTTCCTTTCCATTAACAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCG
+
.@?>7."'3'$+7-*F:/9A,?=*D/?1*5=669;-G$;#'=?+!5'7(=+D8(+9+F1!"H5
@r6242
ACCGCATTCAAAATGTNGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCT
+
=,.F>H1-H$'=;"G1)#HC"@?2,9'7-)5&5;@D.H(($('!!4:@,E-<)1;11+:E;4.?".&2H8*,+
@r6243
AGTNATCNTTTTGTGANATGCCGCAGAAACGTTGTATGAAATAACGT
+
E.7*+,58'H@-104>:%23F1%&@-!*.'G:2?7G=%6;0A'#4$5
@r6244
AAGCCCAACAAGCCGTAAANGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCT
+
(<)H;C!>-?;'1!G2-*<<&6$<=5/EG):<"0@(346?F17);,&%,&7"#:/?CED>!6)6/!68;$(,BG7+3;BC8D4
@r6245
ACCAATATTCGAATTGAAGAACTGAAAGAACANCAAGCCGCCTGATGGCG
+
2:>:70&9&,H)%6-E,;$D5%1*EH:C-/+&/B/-"E-H58>"3$:7$1
@r6246
NANCNACCGNANCTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAATGGGATGNCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGC
+
#&($$()'%!$!)++$(*"($"%'"#!&+))(*('")($)&%($%$!$'#"%*""**!&!&"&+%+!&#"+&*#$++*+#!#%&)&*(&%##+)*&%)'%%'!''++!'+((&*+(*((*('')"!#)+'
@r6247
CGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGC
+
9!$>:@E57+.1ABC':A4@:8?$H;;53!7.;>H<+31<#)30/.?0H?;F;FF6$+&G("!,8H;F:@?-*4?9-)48)#HD;6#",$0,:/:44%B%6>/=5CC24B8.48<F1;FC9>,9DB5C6A/$@118@CF3+F.%<2*76/)/&34)?=665H+H.2?--C6C-1C+)(#-CHE/<%F#0E)/G;C#;>H%B?.%)F#(
@r6248
CCGCCATGTTANTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTT
+
!#%)%'$)%'(!+!)%*#"+*!&%'&$"%&"++##*+&)&'%$+#'#))++("&$"(*+&%&"*%&%&#)'
@r6249
GCTGGCACCGAAAGCCAGAACTCCCCGTATACAAACAACGGATAACGGTAAGCAGAACACCTATTTCT
+
-+D6)-;$!..+2>+$"D%&.D5-H/0/#1G2)&<"+FE+>3@0D3=9D+5-.>;+$D,8121(7)B?
@r6250
ATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGA
+
47GH$$6&4@6&#,0CBC0'DB"AE0(:)/D!9(!-+1)GGG&>H/?2$B6DC;<&&57"D<?"03
@r6251
CGTATCGNCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCANAACGGTTTCGGGATTTTCTATATCTGCACAACACGTAAGAGCAT
+
@)%1>-#"G/1E0.3AC30&)9)%G%>9BFE,-HD;H:>G&B*,D>%<EH$)$F,:+:7DE1/!H4#166+#%A9"D,2(.(:FF4G)3--=7<EF:4%4/D4)-4'?;:!0D=4,)=,=A#DH&/';G5E02A
@r6252
TTCACAAAAGCTGGAAATGATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACA
+
<.9'++B$2+!'*,::+8)C:7"'>E6FB@$G@6%6.,3.@$)@.(=>H9B-E@D,8C6-H:G
@r6253
TCNNTNNTGTTAGCGCAATATCCTNGTTCTCCTGGTAGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCCATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTT
+
*)#!$("+!$'&+&!&')(+)$+(+)'#")'&''+"&$"")')))+!'(+")%%"$*&"*!&""%!#&$%)#!&++"$((!'!)")&%)##&('$!$'$#!''$%$!((&+(%&$**(*$%!*%#"))+$((!!&##+'"+$+'!*!#$#*##(#+%$)%*)!+"&$'
@r6254
GAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGGATGCAGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAATNTTCACCAGGAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGC
+
7G1-@G*68)2'1/*9,#)(=7!7&"/G?8"'.CH($77D&A;F@G;1'8>'D?E#<-$F52@2-94"E=F-;76,45'0?087*$<><2+!BE0*%$(#CC839>41-4257:5#1#=<#>H"/:@9*-1,''0$%/0.6.*=)&77=<D(6;D=@./02$3H$;5-6!1C3-H8/#HB':339*C3!&7*AG?(2?#G5C@9=*6!8F1
@r6255
GAGCCTGCATAACGGTTTCGGGACTTTTTATATNTGCACAACAGGTAAGAGCATTGAGTCGATAATCGAGAAGAGTCGGCGAGCCTGGTTNGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGNAGCAGAACCGGATCACC
+
DE3F#3,73"B$9G*4/'&+C%:4?-:<E:'H'0<,6$.%90/)#CB:G0?H@%&1-,')*D<>0(-;60!7@5<0"45FD*>AF7D,57#9?)H9$$@2+:+<F6,+<+5>$4;#0B1C2A7>+;@!D;*'13-E-86.<"C<7*!/A@
@r6256
TATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATCA
+
-@:/5"B-BD$6-4///B;59<D!GA/&-:91??<AG50*21
@r6257
ATTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCNGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGA
+
#!H":!;;=,@=,4C>)>G<1G9F549<4C5"35@1;.GC7+C.9H!>6(*=E#@9A<;/37=.?#61+9(.),%A"%;A$;A2.&)>'/H5."
@r6258
GGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCNGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCNTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTT
+
B35*-%)%!($:H!C!1BG&D;;=!+A3/(>G97<=4-E.@8/".HAG0945F=&E>G(!9A4-E8+0"29#$#0(-A)5<7)8??@2187<;/'5%%.H*)%=;2H3:.2F@1".A,<5%;$%>266>,';D;)/$GG#%&@E;+(G@<+G8)!CF&1&2%="5&6+:
@r6259
ANNAANTGNNNTTACGNNTGNNNANNNGNNAGNNANNTTCNTNTNNNTTAAGGGNANGTCACGNGNNNTTNNAGNNNTNGTCTNNTNCGTTNNGNNTNNNNTACNANTTNTCNNNGNTANNCA
+
"$!"#!$"#!!#$!#"#"""!#!###"$$"#!!$"#!##$!"#$#$"$#!###!""!!!$$$#!#$#""###!""#!$###!$#$$#$$##!!$$"$""#!"#"!"###!###!$"##$!$##
@r6260
TGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGNTACGCAGGCNATTGCCCATTACGGTCGTAATGTTACGAAGATGGATGCC
+
@06-$B41!#+!4"6#4&(>8=D)89%@0!),50F/:@"(.!$,)H&D;?!:E!5??E>%?G!.(.&-GH&E&<G,7E#%%81)$1)+G-EF&+2('G-''/&=#65;?;BF=8'1:
@r6261
ATTCTGCTCAAACGTCCCGGACGCCTGTGACCGGCNGTCTGCCATGC
+
7&,F=?'CDB/E7",9:@3@#($?:*/&8<,DC0E01B">=1D2'4C
@r6262
TATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGATGGGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCCNGCGGCAGTATAAATGCCTAA
+
'6%F4A9*:<A=BA;8)"1.1C+A24..@9-B(C5*055!2F%&#G&/)(9$<.+D<'/&5<&%-2*)G-CD&G,F45!/?1&E#6&-D'39$*)">EA(9!
@r6263
TNAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATCCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGT
+
89)>9!H6F0$@7&.-->1H1.,3DF*BG71<1#BG<C:8>?',--,;5'264?(4F;5D5-747$>3#C/0.D25<47.+4A9651A77G"9:$-9,2EB.%2?1!?HE-36C,-.FDC&<H/7-&+7'4!H>-7CC,+$(*%E)616,<4,C/7@84/*G#G$@2F;>")(B:@+31B+8+5A@
@r6264
ACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTNTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTTATTTAATAGAAAAAGTGCT
+
1:4==+@73!5@8)(!+:HH6+8BEG8*89F::.0?A:'.$G30!3?A7@#H4'$*:+#(*96:D@"&D49!!:A*5#!+C8;-&4>0'/9=-BE-1=92E.'57+(%*<:B0$<30&*;=+6ED(>*8!,4*"G=7D5-
@r6265
GTATACATNNNCANGANNTNCTNTANCANANCCNNNTANCCNNTCGAGNACNNTTNTCCCNNCAANNCNNGNGNANGNCTGNNAANANTNCN
+
$#!!!"#"!!#!$!"$#$""!$#"""$#!!#"$#$"$"$#!"!!"$$"!""!""#!!$##!"$###!!"!#$#"#!$$!$$$$$###"!!$$
@r6266
TATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGC
+
%!>$0G$BE)>A#,E5>7E349;)0/F47>7+BBB(,&14)92.
@r6267
ACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGCGCAGCCGGATANCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCNGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCNTTTCGTGTCTCTG
+
:60<8FG,5D,-,0>?&@G<G9..@62,>+2?9/G3=E7!)EB:GD5>D7*%6:4/(<*AGE>(5@6B,GB!BE7)=?A-!AD.!9#:.<.8':%D:H8#'</-!<5HG>,!)G-%H)EB3:<7HH;CG3F342-GE?GA->H*&/'G5AF2?4!HC8*>=9=566B,8G*#)'A1C.%#CGE>9HB'10F(5?!1
@r6268
CAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTT
+
/!%*#2B/;;88F:"6=4A77E7@'%=,A5"2?5/;@E/3#E@!A3"'=,$)D
@r6269
ANTGTGGAACCAAGATAGCACTCGAACGANGAAGTAAAGAACGCGAAAAAGCGGA
+
&#-)-/2'8%,"G3#A/8E3;&1/+6&<0"9)@)961'<?C3#%;5H16#F,'*:
@r6270
AGGAACTGAAGAATGCCAGAGACTCCGCNGAAGTGGTGGAAACCGNATTCTG
+
C6+B>!B64B*961D),,7)93!<6,4#0/?'8*G0B/!6:&<%3B:,)%=8
@r6271
AGTGGCGATAGTGAATTTAGTCTGGATAGCCNTAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATAAAGTATNTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGTGC
+
<E:1%7>H?D0/<D#,4?A$@H<H9".$!<=57"C%.$B4.!1?F#$&F'670&3.8&78>C42H<"<3)*/9@29B1@BB94H'@0(.3F*H727C,H4,<D.@>F<$A:'"47*-$C".F=/7EE$?&*!'/#142'36)%4:$===B0<'.&':8@AH,?G=42%-"%$=+(E-"-?C+<03,)/
@r6272
CGGATTCACATGCTGCAGCCGCCCAGCCGGGCGGTTTAAGACCGGCT
+
FC,%14(&E:16'1@7$E+)'4/,"?3-G"FD,<7(B!?:;*'G<$A
@r6273
NATCCTGGCAAGNCNGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGTCGAACCCTCTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTNCAGCATGAGAAATTGNCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTNATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCNACNGGGACATCGCCACCAGAAACGGGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTNTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTNACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTT
+
"%'&(&((((#'$!"(*+!$##%"$&)$*#!$#'!#+(()!&%+(+!++#'%*#+*%')")$)#++##$'!"!(*'##)!)**'#(%"("&!$*!#'$!(%!"($!+'(*))*#")+!$('"()&''"!+#!*"*(+%)$"+!()#$+!$($*&!$&!'%$!+&)+$)'+'+#+')&$(#&)"$$')#(''!*&!''!!##*)&$%&+$"%&)'##(+)))"'%("(&#"(((**$$**%%(+$$$!%$*$")'*'&#!*%&')!!#%!%")(%!(!$%$$(('!'#%!$*&'+)#&(($*!!)+!+#"'"($"")!%&%&$(%"($*%'#'$")*!$+$$)%"&&!#%'$%*$"!++)#('#%))#)!!%'")#++'#+'#%!!*&"(*%&()+$%$$%*##')'#(+)%!+*'"!*)*(")#%**#)*%))%"+!!((#($%"#)#"'#&)+*&*(#'&(!(%&(#)*+&(+$$+()#")*')$((*"((#**$#'!)$''$&&$%*%#*")&*%#*'('*'++(+*!"+$%)+'&)*%*'+#""*&+!)+"*%!"&'%"'+#*"((#'!&#&&+#$%#$!!#&$)!'$!%*(&$+'+($'"*"!+*!(*&*$*(&)'""(&'$'$*+*%&!''+**%)
@r6274
CTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATAAAGGTAT
+
0/0<*D>218(->3;@#?.@@C/$)(G1-$F5@*&=-06"'D-B0-#2
@r6275
GAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCNTTACAGCATGGATGTGGAGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCAC
+
=EF%+(4:4!78!G:F%0,D?F=2%1;)&4=85%&$69$6'+=9*#H+BEF??#<6?2/!<++EH:@$EE)@?"?,2DC<7?;"-(6-;5>H&>=76F&B$
@r6276
CCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACG
+
,)&196FD/E,;87F6,->1?*51.2"CF@F8/+;-1D)G:
@r6277
GTCAACTCCCTGAAATGTTTTTTTCCTTAGGTGAAAGCATTGACNACTATGTTAATCNCAGCNAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCA
+
=C!E!!3D)&;D1DG(%:D/HA3391H%/D5,(8B02.F*;2*E<H9><4C@'4-56*GD;,&)7&1"'#(0-/>G7/D#3%#4?H(7D$>-H>G!?D23'3#:5.
@r6278
NAGGAGNTTNTCNTNATNTNNNAATAANGNGCACACCATGCAATATGCCATTGCANGGTGGCCTGTTGCTGGCT
+
#*"(&"#)#!)&%&!'($'!$##%*$)$)+)&((*%(*&%("#&()%(%)&'$))))&!"*&+!!(#%'+#%''
@r6279
AGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTATATTACCATCCTCAGTTGATGCTGCAGCGCATANCCCAGCTCTTTCGGAAGACTTTCACGCCGTATCCGCTCAATATTTTGTTTAAAC
+
A)32"A50>C%'&:8&:D989<F6)"D/>%F0&+D:C?,GD9$;A0&5FAGF:+(A$+."F'1%<'C4.+&GA:==0,<?>6("9&E"*'&'/&5<>$-D!5B%E6;;/)DB;;:6)1>A!7A+><G%<D$%(G;FE)+4CCGAA;FDCB'=(0,E3#C%20.$-$1?-7%1"%BB*8')>E7B8*1?<4*@B;#4,!&%@%4')+C:,G%CF-.F!'=0>74E/7F$D7/;-&>A7G/@$&66H9:8((&CD8<4#$,A("E;-92&4G789=0021
@r6280
CGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCAT
+
.*B$325A2+.0.+93,2=4;<3>3",&5/4&2.A=B32?#'!'
@r6281
TTNNACTATNANNCCCNTGTNCCTNCAAGGATTTCATGAAGTTCNGGCTCGGTGGTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCAT
+
&%"!&*)$"(%%*")%$""%!$($"%!!+%"((+$#!*!((#(!&$$(&+&"'($)&#'"!%#%!*!**&&*""*'&#"''#%+(&*#+#***!+#+$!&!'"
@r6282
NGATATGCGAGGCTGGACAATCAAGGGGAAACCCGCCAGNGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGAT
+
(1%*G)-=A&H$9!8H4/CB@6"+>44.*-5E,D>..46*F11$=.;51+),B:E7<HD/5D.%#$:)1#:E,=A/FG-1A>E,G2;;3DG3;<G=718(%03-?5;F7C458):
@r6283
CCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAA
+
</&;=*C'14G%*F<-14>@,5$:G>?=*+C?C0H4EEB*$;.1"2&%"*@E6$)7E7@FD13=%E7.<0:384D*#D-;9C=(5"<<<52+(5,&6:@A.4%/5)F9,?H@@9H@&.7B,5&H5=.1&HD4#-AE'?;BD=87;*>,,(/9%:ABA9H$":<6"=H$9+(2AG765310>B#05=#=',0:($3@6;+>3=,A%;2E$C&
@r6284
TGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATA
+
H:.8@'-E>'B':5G5=57=1?-#/H$D<,6;E.3.3,*:!C).'.8G+!$B(1(%%+-<E@%FC;4-&%7,$?'3()C!F6,7#
@r6285
CCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCANCAGGATCATATCGTCGGGT
+
?"+1>AAE,A0.-5+%:27*3G0/87)<%'1?F97G6=G9EE<24<6G5/*"+GA9%2$@@1HH"D?&!+)=5BB2?
@r6286
TTTCCTGCCATCCACCCATTTTTCGACCTGCTCTTCCGCAGTCA
+
3-%"23@+*;C*9=%8141'#8!(#8G$B&!6D&%1*E1D;"H%
@r6287
TCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGTGACCAGTCAACGTCTGAAGGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGNAGGGTGATCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATANCGTCCTNACATTTCATAGGTAATGACATAAGTNAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGNCGGTANTCATAGCCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGA
+
A*4G.)&(@="5'EF9/@FC$)&>2;>."%&,"<0,=G("G5D-A@F"B9*1)*&>?=+CAB;1,&)4.8@!E+="(%$D!C+#-9)'@4$,>!D",'<*#%9%GG$&0-',6,7*EF#9*944D&6A/B21=.58=&71G)G@4H"*#:=+&H;/)*;56)FG&7,>"1(4AC;D$!#&&6=(0)83"8=C;*'"77'FAG'@@3#6%A3868/#3E/8D:AC3E63)C%&'!484'D+#$E:<DH69;92/)-H;A9+)=H*0DH=;GC3B,1582(H+9=/)A2CA@B3=F1.*;%+<7>:27./!4/"B=H.05$90*0+.<2:""&$F)1-$1+F$=H+=B2C8;F"81B(D&(%*=,$C:>!(B3109*CG-?%6+6,++F<-F"*:/$
@r6288
AAGGCCNGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGT
+
&+&'%%()))'#(&+'#(*"!*&#)+)*"%)%!)*$&'$"+&%*
@r6289
TAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAG
+
4G,(9,-*6:9-)(B/!H,7?17<#C-/4,)>-3%/C)A/FH%'E(5:E@5'>(G
@r6290
AGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATGACACAGGCAGGGANTGGGACAAAATT
+
G<2*D;':;@+""E'$)$!6=:#HB8;=CD<%,'%+<"*!2.*EE$@4?+>2/B!<;,$50+2=31E<0!@69D>=F98E*)?19"!/18:/@
@r6291
GAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCA
+
D,57,1,E#D/@>F-E3>'./3H1)H:?;2=@H@*<CB/;#37;A>G&.F85E4G*&8A'A:F*C,-&7$@6#!0D9G(01#))<"F"(9:F%2A-=DHC0DE$'+/%<B%1E535'2B7))&H(>=80F#9!;6H:B-F4$$8.?1,=?%=@5;(%(/G5.D>7-:41+;*CEA9*,D:,8C7,F44,:=/9"$(&<1%,<-)G8+0-D(5$F30=*"97E>5>1')F7&'%,=E"%)#'+)8?=(,"
@r6292
NCAGAAACTGCNTGCATCTCTTCGACCTGAGCAATGGCCAGCTCNTCGTCACGCATGTTCTGCATGATGATGCGACGG
+
!+(#+'#&#*+("&!'$*(++*"%#+&#((#$('(&)#+))*)+$!&$#$$!$)&&(+"$"$"*)$$%"("$"!)())
@r6293
CANNNANGNNCGNNTNNGAGCANNGNANNNNANNGCNTCNCTNNGGNCTTAATNGNANCNNNANAGNTNNNNCNAGNCAAAANNANNNTNANNANNNATAAGNGNTCNNAAGNNNGNGNCNNATCTNCANNCGNGAAGACAANNNGGGNNNNNCNTTTTGANTGATCGCNCNNGNCCNNGTA
+
$!"!!!"$##!""!"!#$$#"###$##$!"!##"$"!!!$$$!"$$"$""!"#$##$!!$!!$!$"!""!$!"!$#$!$$$$!$"$!"##"!!$"!$$"$#""""##"$#"!""!!$"#!"""#"$$$"!!$"!#""!$$"!##"!"#"""$#$#"""$!$!!#"""#$""!"#!"!!#$!$
@r6294
ACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCC
+
.9)+8!-.E=12/!%)G>?!8>!++;;)91%;-5,56*#'E2
@r6295
TCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCC
+
CB%'E7H*:7"7=27!$*#02"H,=D'C>.+!"HDF4:4G6+,80*%*;9HC;17=7F*320D-/57<&;9F/>A%1B'@08A:<C1;7E>
@r6296
CNTGNTNGANGGCAAATACACCATGACCGGTGAAGCCTTCGATCCGGTTGAGGTGGATATGGGCCGCAGTGAGGAG
+
'"($"(!"*")+&"'$)"!&&'%$%"%&)%*'+!!#(%!("'$&(#!*&')"')(!'$%"())((&$(*$)%#%*)
@r6297
GATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGGCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCNCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCNGCGGATTTTTATTGCTNTGTTGCGCTGTAATTCTTTTATTTCTGANGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTAANACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCNTGTAGCTCCCTGATGATTTTNCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAAGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGNTTCGCGG
+
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
@r6298
AGGCGCTGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGNAGGAA
+
F3,*DHA*F$5<9.$B=A:#=HE8=E@FC3HG-8?2))8)</31B<%1$H=&D2G-FH)>F/D7&B$99@G'5*.E32)-:3?B0-!@1.>'"1$90#$>%:"4C0C)-6(&C(44B6<,F&&D,
@r6299
TTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAA
+
H3*=/=<*)2:5)1$@%(&=18"<E3&CB@+*@#&D;)-?<:36G.$$C>&2G6*?G-",/!
@r6300
CGTACGGTCAGTACAGTGTCATCCTGCAGGTTGACGGTTTTCCACCATCGCACGCCGGGA
+
#&#4EA1A2:A9$4112"!GG<(-+;>*D<2)01.#86:%%2%%"57.9(H;),?%+3-$
@r6301
CACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGNCGCGCTCGCCGCCTTTAC
+
C?3;?D7-;AA0+@&7"!6,E=7)==GC(1H03E"=$5+#!9D?%%6/6E,:$)-#EG?0=9<,H.?=&*D1GC**,5:C29%1/5<9)+H#,)($4@/B#;?A(&;=<B;.=6
@r6302
GTTTCTGCCAGCACGCGTGNCTGTTCTTCGCGTCCGTGAGA
+
A3+F$.!0&<&7!#=(G;A5,?!;/5G8<G==D4FB1:$8(
@r6303
AGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTNACGGAAAA
+
@:<H'G880%/:*C%-H;1G$<A</%:<;(7!01+'015.B$B<,23A4;4'0(*:5B<-*%+4E?$G%?.8H9@=9:1H$#!776-09#E/%/3:=B(AC%/.4=?)0)808$1B3.1B0!'.1->!>C,":+
@r6304
CTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGNACGGCCTGTACCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCCTTCAAGCTTTGCCACNCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGNC
+
10/D)#)BH'6B<"#+<)3*12E)H)<269EC-B29.(#0@$EG0",-)+D2/HG#+GAC&)/3;)?4H>C@C*G7(9)$"809%G?,$-4@-&1A)B'7:A0><'!"*7(&/,7#9&>33G14=,6BD5=0&4%A2(<"D)>%/8+0,1:-C?*1'.9C"F:8/'44G02AC.F=+=H3D349:%<E7D?F:-G@#8H/A9F24G/=F&8B!)=0-D/*EF,50(;"9#*)
@r6305
AAGGNCAATAACGTCGGGGACATTGTAAAGGCGCCGAGCGCGGCTTTTCC
+
)#*)"*)&#(&'()++)'"&*#*&%!!'()+&#)"+!"($"#&)"(&%))
@r6306
TGATATTTTCAGGGNCATCAAAAANACCACGTATCACCGCACCTGACTGCTCACCGGATGTA
+
;*>9-8/%D26$,#2'-3D6G7;@'0H$6;@8C2A@)95!D"-$?&-@D=+<<;0)-*)(@6
@r6307
GCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAA
+
-78&3B-$"B+?/DB2-)5"00'A%19?1+9%)!6E+6;8;?.<$,<.0EG),=:#D;G-
@r6308
TATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGT
+
:;1CC7C-D=+*=%EDB<(#31'9.%#3FF5A++4,H"H&D<1,#?!$&$#&:0./.10C9'5-53HD1=E"B."!+D&#=C>:.%ED=0
@r6309
ANNCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATC
+
)!)@H51HBBC$AD40G3G$:6(-D.0='B=4>#*1/D4&B",B=49>
@r6310
CNGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTACCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAGGTCATCACGGGATC
+
*%450"C2DE;@(B(0%*/7@C@B09/?F@,CAF2F!<#46@*7?2.GE<8D9B&F6",C#:::62E&E#9D.!)+HG%/7,;7"C0@G<./D%(33;%A.8@AB3+F,%5?5B3'
@r6311
GCTNAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACCGAACC
+
#))"'+%($)'#!$&#$($'"'$&$+$"'!#'#'$#*!'$%)("'##%)""%
@r6312
GGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTC
+
.BDF>8?FB$,++(+$).>.1C9:F9?H@=2#F<!'=/0/+D<?&=>H?953)$-$+@3G@?=6*0%!?H/%&A8$>$=.=5$49?0C((%0#F681:.,>&3),=@F2A%<<+E"&/F5'
@r6313
GATACTGTCGCCCCTGCCAGGTGACCGGCTCACCTTTTTCGTTCTGCT
+
9;?*,!;(=$C7@6DE;*+'=+>2+=4,#G58B7BC,$)(9/:#%,!B
@r6314
TCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGANAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTNGTTTCCT
+
&+#''"*$&&#+**$*(*"$#)(!+%+$)!!$&*+(%+!'"'!!%*)("&'*"$('(#*$!"*%&')*##'))*"%$(&&"!!""%)&#)"$&+*
@r6315
TTNNNTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAGAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGTGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTANGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAAT
+
!'"#'$+(+&$$++#&*#'%!%%"$+'#%+!)'&*#"#")'(($#%$(""&!'&+#'!&)+))!&%%*'$')'#$*")!#")!'$&#)&"*$%(($#+*+%(#*"*#)')#)(*($#'$++'!+(#$"*#("'*!&"%))%'%%++)"'#$)(%'")+&+&')"#&%))+++)#)'*&#!&'*))%"$*'*++&(#**(*"&$&*'(#*!$)(!$(!)!!!*#$(&'"$''!++("##&*+$+*$+*$(#($**(+#""%#&')!(#*&#$&%#"!$"!"%%)(+'!*"'&#+'**!&+(!*!!$&!')('("%#!+%+&"*"%'+&+*+%"%%*('%"!&+"(%+$#"(
@r6316
TCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCAT
+
'H'5:3D!/AC>5.96%8,A!0?<%ACH<1HC5FEDE+B5?@+!=?
@r6317
TTATGCAAGCCTCACAATATCGTTAAATGCAATGTTTTTGACGGCGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGATAACAACCGGATGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACG
+
E<,!2BB;D1+25@@,-CC&D;7+-0*6="?*7-A5CE:&/43+H*($C$D$?22H;C.?-90D7@<1')!,<!"9)(24F)6@6<?=#<G#=$;A:A,4/+0G8*<8A4/F9C:E1"4<D2$'*0GFB9?0#AG<A&%45'A$&@AE//5#AF5>(<%B3G?8B;"&3'BE#?397)EC:>(HCFE
@r6318
GGNNNACACTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAAA
+
'(!!"''("*+$**#)+("%&)"%&%"%%+(#')!'$)#&'&$*$&)(!+&
@r6319
ATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATT
+
=:4C4'5*87GF>.'!)4#@G/A;7?&)6&:8$C@&:"!D:/*#EA,6=B/6,4',=('66&E0C350&71<:1:C%3EG'C!<#89.$</7*',1D(0-F.H*'
@r6320
NNGTATTTTNNNCGCNCACGAANANNNTNAGGTCTTTCCT
+
*#%*&('**$!!''(&$)%*%*!*!!"'(+)*+&')*+))
@r6321
CCTCAAAACAGGCAGCAAAATCATCAGAAACGAACGCANCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATNCTGCCAGGGCGGCAAAAACGNCCGANACGAATGCCAGGTCATCTGAAACAGC
+
E%:)>=H:$1&DBB/<@@G&:3+?+<1H3/#D@-F8E4<>>)!B(714DF96'/1(:=,H)11G))?7G*5?.FC?4AFA)?%,%700*&>:CHB0AD2,:)<@1!<.8EG&"88B@=!&AAA)$0G=5"FDG@$;96B
@r6322
AGCAATACGCNTACTCCCATCCGGGATAACACCTTCGTAATACTCACGCTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGT
+
>?+39(8G0D,&+&A<.B:E:'-<.A.E),HE'=68=1G)C44*(74G&H3:1%6F*3*(,/;B<</,.A?5+7.3,995#,H,)A8"7EE/"*B835-@9-=A!"<%AG"1*D02BD!7+;#7C94@?E(4.+74503E)@=?G6$$!*+A4&CD;(*74!1?#6E960B8/?%#$,:,5=.;H5)$/%$$7;9"-1!*;-1+-*?757C6@>GG80"4F?H,
@r6323
AGANCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACNTGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTG
+
-E)E%<H6BA495#./(H@)/!9E2!1&!F6:731$#>C652"/09'8'*G%@)!A&:C+""+?//<!FA)>,"6F9A3%#G7&E89B!(5+51B/'
@r6324
TTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTA
+
6F.9@;%DE%<0.077E!%A(0*H*2<3%H/'496%@1(&*C',@7H40.41:29!$#A-9-&9,G(:?/
@r6325
ATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCT
+
4D2?,:$+*FD/G5C)D81?ACAA:>3F@AB68B6!('A?6
@r6326
GTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAAC
+
A*!@@=0(E/D+/#$".6123A$G*3-2>3CGA&-!,<-@B27-<:@%E!E?4'+,?FD&
@r6327
TTATCTCTGCGAGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACT
+
5636H5=)?+?*=3*&63>7#*A*C#>9=(9D;D);48,).>H%(C<;AC
@r6328
GTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCANAGTCCGTG
+
=?<A0'BE=E*E(FGD.;'-':1,+E#C?*:6B9-&'F($C2EDF!41A?:."3@3<C)G)
@r6329
TGTTTTTGCATAGTGATCAGCCTNTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCAGAGGCGGNGGTGGCTTCACGCACTAACGGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCANGCTGACGCATCTGCATGTCAGTAATTGCCGCATTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGNGACTCTGCTCATACATCAATCTCTCTGACCGTTCCNCCCGC
+
DEGD#G%&F55C6=)9*'+G588#%-.=@+*(@,+:ED"'E5DA$C3'2CAC+883-9@.+/8<#A)$;%/EA?F<CE:0'#+(C;'8#%3=3$0&?F0$+,CA!D;F$.8?B.)/D<4,(53B,9DD%?2'=*1CFG."29)C8'E$2*F"":DA9(;7*+"A2.)+5DD&A39#B*E7<F32.1!,'G&788##D843.<8@#<$<4%9"EH91>=6FD'D"%8G?2!!&D3&@;7"/32;/)G"?!485):4?'3"&=?2E3)B'+G3FE61$<E-2<4&"GCD0*?.A$4'D*3(%-!AA>5$0+7/%6>$3C'451+)/;1$>?=@%2-"/C3#5$D12;-?7C1<.5-3-0:"GF70&GG$+>9E&-C$@!>&."H)G$%+69)?4,C.A(FB=:31-?183=%*2.)A,(39)E2!.6/,B@/%0%72)D=61#44*@#@<;+7#
@r6330
TACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTNATATCGGANGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGT
+
6?:'B@%)-B#5*<G->E;,(@7@-=0'=8@$@&:A74$*/B,G%;D1)@+1?$7;;-!9H.>@GDAH8.#)+7<G.#72@>8,&>1&<>$.-1%G'#3<<6!2+G4,H@0*3'.)89C4;#3B=<!C44H$=#2(7/2(9%776F8">FAH*>$*>'6>$9>)B)9/'BH5<9;&'A(1A"45:
@r6331
ANAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGACAACGTAATGCACGTCTTTACCTGCCCGT
+
&!4E5:>5@!3,*8H.-G#'!7B>-8!??>5$:D;BD$G84:,>H+CD21/%?3F</'3:82!"*.?5%7.E%(AE7A0)G#B/
@r6332
CACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATG
+
A'59$,(-,-D60*:/A'H-=+(*;+&&8*B53>=53*+*10G7EH$
@r6333
TATCTTCTTTGCATTNACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCC
+
.BA1&-5DAC(F9D@%D"CC7H)0$CHACE3'E6)G8&0$$D(:"98BH88(*F1>5<'=E(>F93?C3'91)<(
@r6334
CAAATTGGGGGATTGCTATCCCNCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGNCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCGGCAGCAGGTGGGGGACAGAAGAAGACCTGACCGCCGCAGAGTGGA
+
*,+(E*D.7-(,"55<;/61$9";A8'8!#"$C<,3E$"E.4C0)F(1?>4C5)F.4!+H*,2;/+2#*&HHCGD='0'=D2:$@BH+#63*.>F7(<04'1GECGCF/AED+;8C8+.-;$&B&#=&+"**/@)&H-G1:(A,&64<9D:@H@;*7CA@5<%.99E.G-@D"=55D.A9$00?HFC'':8?'6D%!H&<;
@r6335
GTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTA
+
7EF<&6B1'>3##(44@,;$0H=/@;#;16C?B23C&6A,D$*2336B91,H8*63/%:%%DG/AF*.&CFEDB+CC%$70-'"
@r6336
AACGGGTCTTGTTCGATTAACTGCCGCAGAAACTCTTCCAG
+
H4E""A@6,$2#>2@;7/G+GF/F$.2D?)G7%+5!F6<9B
@r6337
AATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATA
+
8!:0+<#>0=+*=,F7)3*FC(ECD%!*G1C.;''D99G?.!?9'/((,1%.=D)>72HAHH4#A2.4$8$E38#%$$E@82-H&FA-%/8,**;E):;?&(&FG9<
@r6338
TGCAAAATCGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCGANGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCGGAATTTCTGTCATCATGGACAGCACG
+
&*+'*#)!#$*+))$+%*$(%"(+!)&+")&&+!$+)("(#(+''#''&+&'%#*'*"!!'%#*'!)!("'#*$(&+$"#%"$*%'$+$%+&!!%%!*")"))&$$&%(%#!'!#*)$)"")!$"#'''('$(#$$'%(++%)%)'((!)!)$+
@r6339
GCCGGGCATTCAACATAAAAACTGATAGCACCCGNAGTTCCGGAAA
+
E>611G:**G+,<G0>&2'DC06#C=AC6@5*5G,$4A=#6E@17-
@r6340
TCATCGCCGCCCAGCAACAGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGGGGCAGGAGGTCGCGCTAACA
+
0C-A+)-8(>E'?0;1,&D*>&-*+="-(B;1B522D<F.AH;3H.63;,"*+GD)9?F1(23E(FF$H"AE)&A715)?#5?@;@$73G+H(%:9")&<854?95)HBB*)2FA.";2(6662,++8-"A:$"'
@r6341
GTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCNGCCGACGCTGCGCCAGCGACNGTTCCGCTGCGTGAGTATCCGTGA
+
)'-C+*58E)5.7%4@H:3!<G??,<.>8&#G(D1>+10AG<B<6(AFH&#,D3(&(=$1,3<E0!@*;"/<8B;G4292*4&G=,-D)&941/G;0&?!*C1#<D3<9A.BE)>@C*=:6<
@r6342
TAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTNATCTGCATNATACCTTCCGAGCATTGATTAAGCATTTCGCTATAAGTTCTCGCTGGCAGAGGTAGTTTTTTCATTGTACTTTACCTTCATNTCTGTTCATTATCATCGCTTTTAAAACGGT
+
@FB?$C<#,:!-B#&C.&?889>!:9)>*?AB,HC1=C$(D'E58>&F?()AC443$)68>!H-"@&@=D7)2?)?"7=$.1F544E"9"E'B?':0*;+)#)..%-6HH<?%2A,-5@376@=H0&3*)#0=$&D78:=>4&2@+650(C841F8#?3GD>'D39=H/0%E2E!%&!"(<.6@:F#%;5D33;'"&5?77!&5146:1*:8A20%(
@r6343
ACNACTAGNATAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTC
+
#!'&#($##%))'%+!&'++#+$(&*'&'!#%%*#&&+##%*'**#$&)"'+)!+$*'"("*!(("#!"#)$*%!"&!))&%+&!+"))$&(&+&'
@r6344
ANGAAANNTCCNTAATAANTNNNTNNNNTGNNNNNNNNNANAAGGNNNCNTTNNGNNAGTANTNNNGNNTANCNATAACGNNNCAANTGGCGNNCCGTNNGNNANGGNTAATCCNGNAGGATNNCATCNAGATTNCNNATTNNNNANNGCCNNNAGCNNNNTGCNCNGNCNACNCNNNCCGTNN
+
""$!$$$"$$"!$$"#$$#"##!$"!!!"$$!!!!"##$!"#$#$"#!$!"!"#"!$"$$""#""#$"$$###$$#$$#$"!$$$!"!#!$$"#$#!"!!#!!"#""!##""!$!#$"$#$!"!"#$#!#!$##!##$#"!##"#$"!#$"!!!!$"!!#$$"$$#""$!$#$###!""$!$!#
@r6345
NAGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACANCGCTGCGCGAATATGCCGGTTATCACGGCGGNGGCAG
+
"$@)4G8H;#@B=35?"07);&323'1&=.8E)9$*,@C*A/'<7/)02?)8@HG+;F-.1+#$C7C!7&?;"@0%8G>:C%54*CCEC0B:74(%%BG
@r6346
CNGNNGTNGCCNCGCGAGTNCCNNCATANNCNNNNNNNNTGCTNNCTCAGGTGTNNCCCGTTNNNNACANGNNNCAGCNANNNGGGCTTNTNANNANNTCGCTNNCNCCTCGGNTCCGNGNGN
+
$"$""##"##$"$"!!##$#$$!##"!!!!$!!#!"""$""!!!!$"#!#$$$!$$$##$"!""#!"!$$!"####!$!$$#!$$$""!$$!!"##$#!$#$"#!"#!"$###$##$!#"##"
@r6347
CTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGTCGGAAGACTGGCTGCAGGCAGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGGCACCCCGGTGGTCTGNCCTGGCTGAGTGAGGCCGACCGG
+
7246==0%/10'57(<.>$!CB=3;<H5:@2C%(-#'=!*C9=G',BE?)G4F7'($7%<<&#(G3;*5",(=G9?E&2A9G+F$=<BD-@A/42/7,7(3:+1'$<93+<A/#D=10&"397D07H78$<+>$9C:?$7'&(G="A$H1%2B@-%,2C)<B7E##-G*8;-!,)9AH?*"7HG,0&(7'3>+=;(41"&@9@3%)!:;(3"7@=*-2'#B<?
@r6348
CAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGAGACCGTCCAGCGACATTCTTCCTCGGTNCATAATCTCC
+
-H0E<@8;;-B=82A+4""(&(/.)$9&09A%$#0=@2#2(-A1=8?66#5"<=G4/'5:1,:G'9G9.5)=/(0?
@r6349
GGTGAGGCGAANCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGG
+
%55A&(12D%&B-G;HD63<?07"*/6C<480CE#-!%/=9>G;D/1
@r6350
TATGGTGATCAGTCAACCACCAGGGAATAATCCTTCATATTA
+
9%:7&%#)+7$E5$0;&@(6+?-%A%>#$74G$87!6F95C3
@r6351
ATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGCCGGACCACCGACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCT
+
8AB*HG"!8;-51A=C4/(<34+>8.>0;9@GG+'=D?A8*>*B-'7+"D"?7F:/6FD(3/$.3%2*!1EA%>E?*'&./%'@@"'E"H101E;595)!+"-6H'5>)3H!8CD5;:@<+6"3E"60;/78AG.?B'(7@&+6#;9H;/!!?(3.=.%B,83,1"98G6&!EA!=*&'!?!2H7++H)-
@r6352
AGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCAT
+
)C+GF-<$H'?G'D9'8C/38E-<'8$2;:2,E-)H68D+
@r6353
TGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCAAAGGCGGGTTCAAGCATCAGCGGCTCATTAAAGGCCANGCTGGCAATATGCGGGAGATTACGCAGGTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCA
+
*+B;/;%;)'#/8;&(#*<!!;&&);G90*;0BA99@$*38FH7/(<20#0?1*+-!5)G(E/E<5)E<460,+,;#H>7;?**;G0H<%4*+%D'9/@=A+)-A>#7!/-7B*%%=(>*<)&*<*G74$#GFE/<1;69A/FC2@$C8F(
@r6354
NTTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCNTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCNCTGTCGGTGGTGCCATCCCACGC
+
!!6>6,D,0B2BG',.<"@,'A-DF#"#"9.*&<0G#)C4H+)5D)FC!"0=6A/BE(1*-%5)8$.*:E("%@:?5'#<H4-&(*93:"*#/2(@.C+#9,26@4?3?=#<?C"::/+4>:3:%8$
@r6355
CTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATACTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGGAGCAGCTTTTCG
+
9*'62A&9E%;D2',E1<+@.AH2A#0#>!6=*<11H4.+3/A(5'398)9@<5G!6/&&@9G9(7G"+:4H$=1!+&F533)39#*&G,C42)%HC'H?/;/
@r6356
NNCAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCNGTATGCANCTTCACCANTGCCACGACCGTGANCA
+
#!&+#%$!)""%%'(%"%!++($&###+%(''#*##$&"$"!'+$&)+#(()+""*"!$%$+'"'%%(!!&#*&$(*
@r6357
CATATTTCACTTCCTTACCCAGCACCGTCTCGGAGCCGGAG
+
DC)"B"-A08->C67".C5CHE$5<2!*)A4=!!&,>48<(
@r6358
GATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCG
+
C/9!CH.A@:A.7/5H*464<"*;41.34/7#))A;24CB@>;")/
@r6359
GTAAATCCCGGCGCTCATNACTTCGCCTTCTTCCCATTTCTGATCCTCTTCAAAANGCCNCCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCAT
+
?%*6B@$@66/)7(<D.$A8A)G6/+F8&=B$!=:#;6B=,!.A,#=<1-E0C%##@2C=F8.%3@#:H,-2):A@?!+C+99,GF#=8:,.=?HE)"/G!*6.'2?!(@'16B$1>:,F%+,0
@r6360
CACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGAGAC
+
/:,=!/:."-("B>B"7'/<47+4</)18G+/:'96(-@H0C#.9&1'21B-*"B2>?(EE9.80%?9&"57%':,81,E"1'HA3>&?7@+.(A2!%"AB6>:,3:E::C(@7$3&3'@
@r6361
GGGAGTTCTGGCTTTCGGTGCCAGCATCTGCTCCACACCACCGAGCACCATAC
+
B-424G-3,;4(CB9-(4?)C;34.-'FD>0(%,-!-@6=3;BD3C"@*'C/!
@r6362
ACAACATGGCCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGNCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATG
+
8:$'G0+<6A#52""3(HA(4>5F=+=0*G3$8@".*'>7A)#G4A.+"F;96:@,?H&:(+H,G0B677=659>!G5A/#="!E@ED&+?9,:#8>&;
@r6363
TGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTANCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATT
+
.BH<&;CC,82'7=8;.=D2@HCF=5.EA9:?!4A,02B=8":H5E8B?@/CA#+2)E.%9ADG$AA+"D.E!5#A!=BHAG3$E.F3$C.&
@r6364
CTTNGNTNTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCNTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGG
+
!!'((%)#((+%+#!+))%&*$)'#((#"#)"#&"%$""'()$("'!*$!%(%&*()"+*!!)(&$+#(%!+("(!"*#')"&"+"+"("&%&'!%"(''!!""'%$+(%(')''"+*%"%%*
@r6365
CTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGC
+
E(7H+5;'A+'5&8+989<+?4@C7C8=>+)7#6:GD,))%H(<A1/.762(4?3(B,309@A">3+!-;@*"B;*8*8D37?BAH1B(B?H<5#<%A(0!->!<(9;>+/46=@@*FE
@r6366
GTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGT
+
&6/%9G-;'?>/1+!>+/>:!<$@,+=;:-"</(8FDEE=,9E/;+>+<4@#GH1$5F&B5<?FD426;(2)6!('0B7=3.@>C$"+=$>5E(,#.AB0"<!17'.EG+@":/E06%0F@%)*
@r6367
AAATTAGAAAAGCGNTATGAAAATAATCTCCGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCATTTTCTTCCTATTGCACATCATCCTGAATGTTCGGTGATGCCTATTAA
+
4F5DDB&06H5G0".!)1B"&''?C(%.@@2#,-&%&;)D$!F?FH65/.DEG'H;F5/H4(7A+$0$9-(:H5*E<;"/)#A""9>D))EFA8D.2!,+.+B(%B@+)#C@5C%3AG.&='A2<)E.,<#6H:.D9&!6:<C?7'12&B7%%%"9"G*!*0-$7@<E=E9?;&;*="+.<FA5&
@r6368
AGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTT
+
:$+/2>=/-408&$>7!&<+<5;!;*D,GE6!<291!>#0;?<7'(=,H/?:5:>B$11E-80'"6+E%4DF<B(=G$4$0%;/9
@r6369
ATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTC
+
44?BE('!2"2(!%+-2.:"'$+"0AG@2!3.5FB#.A!'BA#4#GC(999:GB-H0%?E8"?(H+236/=*+038G:D4A6;=/6.+"1#52!@-F0
@r6370
ACGGCATTTAAAGGTGATGCCAGCGATGCGCNGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGCATGGCATCGTNCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGG
+
592B)GHG;=.CC/-8'7,%0E.,8AHA?HB.0)3):H231!H&*E%)H!/4'E14>".:@9(<5C)5$:>613,..?75!3'=.E60#6H7.'"E9E>@6#D'31F@$<,%0&(2-%4E=,4+>B23*CD92@#539.?601*&*<5B4996,./8/D77()AE?%,6*39-"!<4%-A8+0/>E1">F0%45FB$E+/$@
@r6371
AGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCNG
+
82$!<GD+A3)A#H$%DEB>D5)1=5:-<.@<201)==;;-55H3%7*:+'87-#=:%6=)H+=1D1?DA2=,E/9F1*=-HF!1/?
@r6372
NNNNNNNNAGCGNACCGGAANATNGGGTNNNGNNNANNTNNNNTTGATCCNTNNNTAGNNNNC
+
"#""!!!"$$##!"$##"$"##$#"$#""!"!#!$!"$$$#"#$"$"""$!$##$$!##$$!#
@r6373
GCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAACAGTTCTGGCTGGAGTCAGTATGGAACAGCAACCATTACAGGAAGTTTAACCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCANTGTCCGGTACAGCCGTG
+
8F=(.%044.9G+;;"3:&?60?:?(<B$$E,88C,8B6#$FEF=861!B$)*2200$&,"-@-FH-+FB:"4A+/H6$,848(/H:E"<A/(8*"=84@98))*8?.A0GE)H,6+1!(10<;-88#H,"/E>#%?*;:8$DE<"07;CBAA7.2'/+H<B,-F>/C&.!.9=3&6;(4*=C
@r6374
GCATGTAATAATTCGTAAGCTTTTAGCGTATTCGCGACCCATCGTCTTTCTGATTTAATAATAGA
+
>5,D:*+)A7(1-*9H:;>C>.2ACE,:H6"2&(A(%?7&E!5E73&AD2<;%)1=)E90@9;8H
@r6375
AAACACTGCCCTTTCAGCGGGCCATCATGAATGCNATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAA
+
>?';,F<2)9?;05C3G<#!H1$;?4DC/+03.F&=25A0?>4&=''8#)30.+%+?<3(6-+0>D3,@915<.E8DAAD*;:H"!<9+EEC,*)-)"H
@r6376
TAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCCTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGNCCCTCGACCAACGGCTGGGAGACGGCGACAGA
+
-='@020-G$E)+=!':#3A$C44D.H.$<@>3G<<<+H5'!B(G.6854*02H>C8G"';10E6DF26;&F/-!!!B$D/70?71-"/.%H,A4;AE.+%<>)*)!8=F8;$6'@&"-D8$!'5//#1:06860B%*
@r6377
TGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAAC
+
.=500<!(:344,'%D)*#1?#3**"A4-$0+%<82;;7.2*1FB=A):5:?(0#1><;=C4=
@r6378
GAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGCAACCAGCCGGATTGGCGTGGGGAATCT
+
/-=G;(F#@?65*<C(<@&4B.:AE&AC$:,?B1$:4;8)<%(6,.8;*6>%$3.#+1%H@"CE$G%&#0#;%AF.G0D':!B<9$)<(<@=?@
@r6379
CGTTCTGCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGCATCAATGGCGGCCCTGCGTTTTGCCCGTTGCTGC
+
9-!DA%AE,A(5AD-/-'%'97:;66+HB8/B*&6:@,8</G@'77E7>"5-*3@#0?$,%A2AH(;*<':@
@r6380
NNCAGGCNANGCAATTGTTTTATTTACTATCACAAGATTANTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAATAATTGCANCTCATTCCCCAGT
+
!$!!&("&)'()&+"+#$"!)#+&)#*($"(%!+*++"'*(&('("%+#%"*'(!#!*!#&*!%'"%+$!%+%'*$'$'&$&+$"!#%+#+'&('%!&%'%#+%()*"&(#"(&*%()+$&(#"%*()#!+")*"%$')'$)'"&!())*++"!+"'(+)")!#+%$#&(*#'(%&%(!%%%&)$%)()
@r6381
NGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCNCAAAAG
+
%1A/+)A*!)46A-E%2945=7-*F$9!:)5155E6/1:#@7$0@4C&E$.)G="*4AA96@
@r6382
TNNGANACAGCAGCAGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATCCACGAAGGCCACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGTGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACAC
+
#&'''$+*$'+&$+*+$'#(*$+++*(('()$'$!$#"&'!"!&#&%*(!%*$!'+!'!%"$#)"(*%*&&)''+$&'+"!!)"%!#%!!$'(#%+'(&)+(+#*'&'#$(%$)'%+"""('(++*#%'&&&+++%!"&+$&"!%&"))#'%$!%*+##+&&))"&'%"'#'(+*$#(!%)$)*#*!+'('"&!(+$$&&)++!%&'#')(+!"(&"$$!&$&(
@r6383
CTCCTCGCTCATAACAGACATTCACTACAGTTATNGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGNAAAGAAGTCAGGTGCGTCGTTTGACATCACTGCTATCATCTTACTGG
+
$'*B99(F(B>>!>FA@DE95FC>3!0=89)9!>B2!*G'%CDA:2."$31@?#."E%AC&*6<7&D?/&+(&@C0.,H@=C;7/:GAC0-E/;98BC;48@=/:F8)FDD+CD(F)G!<)1H&
@r6384
GATAACACCATCGATTGTGCTGGAACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAGCGAGGATATTGAGCTAA
+
$!'&'+&%#("+$%'+#*""+'%)*%+'&%)+'*%*&&())!#$)*("$)$#*!('&%("!!(!"%*!'+($+"+'(&'"($+'!)**('%($&'!'+
@r6385
NTGTTTGTCGTTCTGGCTGAGTTCNTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGA
+
"?.,083&",!32EC4>E3&!*C8,?)#6?>,2"?D*&C+F482C5.@#0B*"#<G)CH(0@!C$88C.&3@:-A036G)-$*%8185-EE=)F6:%>%,8$:1%%'75*0*#14E(8*1G:<#23+A"B<0$GB
@r6386
CGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGC
+
E?)48-/51B5)C;A5/%&"7:B2A=)-E..D61=>F03*>0(@0B2$#1A-"'E5:81D*!@38,6,"+9F436C'
@r6387
GAAACATCTGGCTCGCNTGACGGGATGCGACGAATTTTCGCCGCCCCATAAAGTACGCCCACGACTCGTTCGCACTGGCCCG
+
DA202)"'2B=EDD$1-D(:?=92C;$:&#%#0@9/E(#6,=:A4$;7-H:E";A)-=DF-%%:!G)F)BB-/9!D'-?<3@
@r6388
AAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCNGTTTTTACAAAATCCGGTAGTAACTTG
+
)+-A%7.C8,H8.E?CC*%D)?,5A<F?"(+A(F+$:*F69::22)39/E)1*3/:G.>:!&B"D-;85#=0C*,??&B
@r6389
TGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGCCGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAA
+
73"HB/=<%-.H@'D)!6*B@>1H),-$=1(6?@278..35,B3.@10#(B1G/<(7>3-'%-$12"A@;2>23/;51!;-?.<
@r6390
TTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGNCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCG
+
3&691:/:H91;'&7:1?>!-DF-,#H(!=F:A:#(C75#-;"C?&;2";/')?A>>.9=:0B*-7:+G&3*F/0A763,5G>8293?"G;F':4(H(.F6,%A"5%9'F#,,@0:7DA6166,1H1$$1CFHHC6%5(#>7+6F#E:750#0'7::'*F:6E-2A*-4=5:5DA/
@r6391
TAAAAATAATATCCTTGGCANCCTTTTTTATATCCCTTTTAAATTTTGGC
+
FG$:8AC?<#3%!:--D%0D$!?B2;507DH")$;0D4%C2?4-'?4=':
@r6392
TATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTT
+
2=A%A&EE5DC'/D>,>A)&;?H<CD009+<9?+7>;@.B@B49DG+6D&&;4,1G$==%<:2@@4*=H0
@r6393
GAAGGGCCATGATTACGCCAGTTGTACGGACACGAACTCATCAGGGTCAGCCAG
+
H?HE&6"-!=G)7+3B>+$"673:##@<=.1G!:#3-D1C)-8=$F=F$FC8,C
@r6394
CAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCNTTGATGCNGAAGAGGTAAAGCCCTTCCCGAGTAACAAAA
+
+)"$(#+(%(++$#($%"'"+#'(*'(($&+!#!$#!&)%)&%()+"#!%$&("!$+)%+%$'$%#++&"&+!'%!$"$&"**&")*'"#*+###
@r6395
NTAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAA
+
"?61:C&@0?;H'8!GA2*>D)FF/>6'#2+!GC=;;E,+9'A
@r6396
AGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAG
+
H1#.-5330*#"@2=):B'D==-447)38-H03H.GA=<3<'E.'#'*%#45+=
@r6397
ACGGGTCCTTTCCNGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGGGGGTGAAATAA
+
5F%6%%4@13H/F0D9*)>)!&B5!-+-9))0%)$!",D4(G51?!AG*+!@B0&7F=F*.':G*&+"#+"?+@$.E>"9(<
@r6398
AACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCTGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGC
+
HD$.&H**6/$</BB/9'C%-9$E0%9H@=)0)-*/2==38;8=&5D5"8+;7<<DE32@&<;A,)'9A#23*D/H/>E19!66),701;2GF2,@.7)5FA/(84/=EE<2>""D*C48"
@r6399
NAGGNAAGNCATAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTTCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCANTTCCTGTGGGTCGAAAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTNCGANTGCAGTACTCATTCGTTTTATACCTNTGAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATNTGTTCT
+
($&&"'&%'($*"%*(++&!#(*!('"#*)!&!(+&)*(***+!)(*(("&"$#%"(+!*%()(%(!$"#(+&!'#'"%"%(#+')#*"(&)$%()!"*$*"'&%"+($!+(!'%(+"&+$*'%)''*%+"&#""''(#()&"*()#++"(%)*!**)'($(!"!&'!++*!!)+$$'&+()*'(%$%!+")&!)+%*((!#+()"++"%+#)$$"+)+%+'%'+&&$#)*$)**('+'%()""&)')!#&+$&!("")'")+)(&#)!"!'%#
@r6400
GAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCGACATGGGACTTGTTCAATGACACCTCAGCAGG
+
'35B/)8*C)E!)91('85D0''B6:2%GE:;5@A8)4?HF8A1(#(-H!F>97.'@(*:B+*5-*F9&B$#+/#8.0*('6++'=5#%,#C5---'&*!D>=4"A575=,$*D%>"@$
@r6401
GTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGNTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATNTCNAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATAC
+
+!*#')!($!%%")))'($)!#+"!*#+!"*&+"(("$#'*)*"(+!*+"')!&++"+&+&%*%#+*'#%%)*#&+)'$&+%&'&(!$+&#((+!$*%(#)+'+&&+#%%##$''$(*&!'$(+)*!('("(+)#!)(#)")"!+&$'!++&$+%$!)+"&+#%)#*&$+"'()(**#&)*%*$(&)'(**+"$#)$+)(()+($!)!&&&*$&!%'%'%$!%*)(&*($!(*#%%$'+)
@r6402
AGTGCANCCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGAT
+
(**$(*!&&+++'&(##$$%+(*&!!"#()+(%**)")&""+!$'"!$(!%$+)&%&!*!*(&!)%
@r6403
GTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCACACAAGGTATCGGGGAAA
+
C<)#B3G*F?@*89>/)CE,F/D,<93H2>((630;$!%9/.3/?@H17)'27C=;60F30/.?@%-H0,0)?F>(H+F'
@r6404
GAANTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGNCTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATGGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATAGCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACA
+
-'76&H-#@%F%.?5#61F:.$7)=.2GE2+@!#D)&*'@G"9G>.C8;")-=1>%A8A1(.A0.C9HE'0A>>-'6>8C=8$+"#26:!.E"@=B@D!-$2=7D@3+C6?F686@5>!!F:></G9D#"A#89094+A2E33"<!&,+H#E;<@!E@6='!)$::'#3)&;=5@;"$H3;8()?B7%"0E0@::,C*HD-$./3#!;%HF*A#H-:C*84&2<3.D1"E9:F49G):.B&5.6&$(>EFF+4)<8">%!C<FD?)BA'9(4"
@r6405
CTTCATGCTTCGGCTTTACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACG
+
4-=D$1DDB>2G),59F#F=/&:?@'B/2%>5/&(.HFHH@$@>&C8+'5+(7%064F*'8
@r6406
GACACTGCGCTGGATCGTCTGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGNTAACGATTTGCTGAACAC
+
,EC:<4&5-B(5H=G8)D=-//"@@9#!763)6@A0&AH?*50,-C&0:9B39'C?';!4.B,3"/B$9#&?4E<,,>,9=:5!CC4/&(<E
@r6407
AGAATCCTCCTGCTCCGAGACGGTGCTGGGTACGGAAGTGNAATATGACACNCCGATCACCCGCACCANTACGTCTGCAAACATCGACCGTNTG
+
#54"(8*D@8-$7)2):>8>"!8<D!G#DH6?!#6@=46C8?7,E'21@%'(4!8849H>F6*?".*2.8<!$63@)0")%H"<1+F0+)H"5*
@r6408
CGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGNCAGCGATGTGGAGGTTATGGTGATTAAGAAACAGGC
+
'GE#B'H9C9#--A/".!(,5.'-0?7#@':AD2D/7<&H;=:5:<F,,+>A@<*B@-7<+%:AE,#H+4*@D<0743B
@r6409
GGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGAT
+
60.C99"/)4/$"/*CB*D!?,5-7EG=AFG!HB3AF></:C7H9)97A/
@r6410
NAGACCATCGATGGCCANACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTG
+
!;571+='C44#&2+<7E:=5:<)6+F6(3EA@@<)7C%HB%?$-#"'=6?'/F*8;*
@r6411
ATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATT
+
EE/+.G%@E?:%+8.0(+"53.!5E9/)>B%!G+!79.FBEG7
@r6412
ACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGG
+
H$6@C(9G+!:,"5;!C'#70.-B68+2,#<(F)558+30@&$=07#&A&7.
@r6413
ATTTTTTGTNTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTANTATGTCCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCNTAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGA
+
/C@:243??8>-:0?+3F./"?<#!?3@A:-H-::B)*&E2,@C3B(+4C0BG,7)595D@<4*'E3F@.4D>"&H2,G4%C/HH/"G1DA-("F-:A!2>A4,HG*+"3A7CG32<<))890<(5E=?F&673#)-+;+&-?/,)?-#6'+.@*2.7?C)72+E04620()7>/!;7*'F="B#:('?$;#5F)G.3'9CF51FF+(F%
@r6414
TACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGC
+
F/$1=BC@E22$:>;'D?D@6DH>-9"#((BC-3H+5()53%<HCH0G1:F5>!F>!78/1;@E/0+GH45/
@r6415
CAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCCCTTCGCTGATGGCATCGAT
+
>?/E4'-(B;756DH/.+BG@E7+)8)F11;4"8;2#2D@).+0!%@9+E*-4),.0+(F
@r6416
TAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTAT
+
6.G2H+85G!25;B.3=)@6*E206(?E#G>@1>+A&()5253:;&%&.8:/%.>0<=83&$F?49@H7
@r6417
CATGAATTGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGNATTGCATAATCTTTCANGGTTATGCGTTG
+
+($!$#*)'!)"#%%&!%'+%"$'"(+"*!%*$!+)%%*%#+$#''$('$(%*&&($$!#&%"!##)+)#(*$!(%%""))*$)$)*&$+%#!$#&+&!*
@r6418
AGCAGAACATCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACA
+
5)5B0F<!!,>D7*(37"ACB+:6C"77F.:5F$)")D@%G2@@,G%>A-#<0(?&#%CF?G!4=0E
@r6419
AGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATAGTTAAAAAAATCTTTCGGCCTGCATGAATGGCCTTGTTGATCGCGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCG
+
9H"E82:;?7>0C*!'3F/F:.H.6@1E/G;,-B*"<<6G0)5C*G,B0-1'$#F@,B1GCF<01F(C.9&+$>?-,9#&(;&',42'E<2"34F6:2%88GHG0F=2<=%&?(@)#D=9D5)8?@>E*E#5:%A4F=+17"%)1*;<@=A$5A;*,+1@@-.;=&0#9E>2/F7;8*+-63);/B8?+44'?9-<3D*0D%:
@r6420
CGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCT
+
9+6.5/6B*GE"83A>A'E>:?B!1$EFA+B;>D2'>"F1&+3)<4
@r6421
TGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGACTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGG
+
>@4>!*-4%?,$4C3.@+)2B0)<.#225A4%E5H&3''4H7D(<*)EHD"*%5;9'$5+0.1.+=E"(4-G36%E&,'+0-!A%2$7'=81B96F*(A>2>#/$-&:)H.;EHB/$<;2/,1.>@8E,?2%$2;"30%8&G#G-,7-!4(%,@,")=AC:94.@*H%7-6F7DC;G20G%A@#)*5C2<%$G&6.)@C/F@6=!?3$*4D;A&38A*:18*8"HB;G
@r6422
ATACCGGCGCCGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGTAGCTAAANTTCATTC
+
:F(:)"+;<-?=./?9?@#D0$&;G;%7>1,78::>*F;E&+$4?DE*:F<#/<%"22E?3B=+;E;?F.BG#C%9GF)#/F.:>7C<5!
@r6423
ATGTATNGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTANCAGTGCC
+
*)*'*%"'$)$+$)%%(##(*!'(!)"$)*+*#""$$!$#**+$#!)#'&"+#)*)"#$#!$#'#$&")#!')""("!"'
@r6424
CNGATGGACGCAAGCNGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCG
+
%*9&*#2)=!&#0,915?;85,3%F+E!&'AC?!@DHAHF57!0@4>60A6+GC+<#:BH>
@r6425
GGNAANCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGC
+
'&%&$!)'+$%%"$%%'"%*!*$)&&&%$""#"""(%&**#$!''"$&&+"&"!*(!&
@r6426
TACAGCCTGTNNNGGGNAANNGCCGTTACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGC
+
'"*%")"'&(!#'"###&*%"!%&((+*%!'($)!#'%)(**((&+*#"*!$!!&%)!&(*#)$$"(*!$&!!'&)(
@r6427
ACGGACCGCGTTTGCCGGAACGGCAATCAGCNTCCTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGT
+
@2!1*HE1A-<D%'9<:H(B($0#D6()%#-#<3%81)$EB@;6'7/6AC?*'.1'77&&9><8(85@86:7H1=F42@"'?25@%==*?.#)
@r6428
CCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACACACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGC
+
F?"<D'-,F%G<E$E,B25G08/?4F127/$%?+9?(,.-H+*=34/B:%4C'"2H!G6B)-%58*%.586&+>83C?"8*08EFC2)%-4GDB1B=0EGE695-
@r6429
GGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTT
+
5:@23?"7F3C..&$F41@*#C<B,&4>6;:;:D%G9G!;D/7D)B8&(H,E,C09G!;#/F+.@GD);BE7+9H6F#
@r6430
TACGGTGAGCGGTATATCCCAGANCTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACC
+
945-GD:54(7C1DE91'E)8=(&)"95#.&5?*-.%.A&?/*D/<'1;<H?A#=*A%;@.=;3(C3@<7,'
@r6431
AANCNGATNTCACTCTCCTTTGATGCGAATGCCAGCGTCAGACATCATATGCAGATACTCACCTGCATCCTNANCCCATTGACCTCCAANCCCGTAATAGCGATGCGTAATGATGTCGATAGTTACTAACGGGTCTTGTTCGATTAACTGCCGCAGA
+
)%!"'")(#%+%%$'%*#*&%'&%"%*!!***'!%"&!**!++(#!!!))+**&+&%#+*!+'+!)&"!#''##!&%$*)!)()))&*+'+)$$!&%&)%&'"%*+!!$')$*&$)"!!!$)%%(#*)'*&)%''()&%!*+$!)'+!$(+%&!"&&
@r6432
TGGGCAATACGAACGCCGGCAATGATTGCCAGANAACTTGGTAAACAGAAC
+
,3!:75E-"7'GHE.+)<9?+.%,:?-'#8(3&!B8?7"-70A4;+'EB?"
@r6433
GTCNANCNTNGAGCAGCGCCGGGATTTNNGGAAGGCGGANAGTCAGTTCGCG
+
%!&$)!'#$#+%!+%!(#%*)$!(*$+&$!%###&+*+")')"*$$**%$$+
@r6434
ATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCNTACAGTCATAGATGGTCGGCGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACCCCCGCACTAT
+
#D1H:#G%81-%">;BH"C"/E"#2.0#-6C(!2BG<A8(G0*68;CD1'97$&H#HF8,8(G+$6*3A%)839(*-C%E:"6>!B-#H(4AF6G+F7@<?+=C:B(2#A?'$*&;!#<96'26:5/2GG1G7%*(7&
@r6435
CACTGTGTATTCATTCCAACGAGTGAATACACGGNGCAATGTCGCTCGTAACTAAACAGGAG
+
0D)+HH%+%G:2E.F"'&,+-.=<4;8>=HH!7C2:3/):B1=E,#8+D:D;G9A29"(<@,
@r6436
CCGATGGTGGGGGCCACCTCGCTGGCGGTGGNGACCGGTGCGC
+
937<),1.$F.(*#D:4<7/&H"G$G@9=,.%+3'BF'5.-!(
@r6437
GNNTGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCNGATATCGT
+
#"#+!!(#&))"'$#('#"'$%)%#)++&#%!)$)+%$*)(%*'&!('!"#
@r6438
GTCGCCTGATTTATGCTGGTTACTGTTGCGCCNGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTC
+
>?8G0-50/!3$&73?:(,E(;"%*-!"3:1@,2F/*%"(C:;E"GA;10/8:EH8H?(C(/(5=EBF=,<);"E7H5;%:.CG5%BCG$27,&*'("H=:=44*?D!'$2H<!8A,5198H1/8
@r6439
ATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCAC
+
D#:;:60"0/,G.0+%"!H,H"&*0B?"-59"@745:*H/>6%F';C*</G"=,!/3+-5713)"*>E>2:7-&2.4'8G077)(=<5./
@r6440
CGAAATTNGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGAT
+
-1A.1D0;0+GF$*C1$H>'826B&=C:?6'=):15(*;,<?*D##.50
@r6441
GACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGNTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGT
+
6@<1!9.H$@C>&9"G@<#H-=/F5'FBG-H%8%A0:61.0)E&()>3@!GF>63/=E+>14=<.G0@>."A!&G7"?57B*(7F5#;=9+:%%8:@!$&F"#8H9./F7!4>;>;80)4B9H6*,.")@55;2CGE8<F69"9?"G19+$@*=C&,4H';*
@r6442
TCAGATACAACGTAACGGTGGCTGGGTGACGGAAAAAGACATCACCTTTAAGGGCAAAAC
+
77D)DCA@)'C$<1D*B9F4+(C'6"2.&:)/80A."9,78;,>=#DA,2H7%!B?D6<!
@r6443
TTTCCACCAGTGNCTGTACACCGAAGGTAAAGCGCAGACGGTCG
+
47'$;(058.2?'(B)7!(8D<=D.(*?A>C:*:&:'F-;*<)F
@r6444
CACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCT
+
,?*"<HC4*#%FDD@0.7GGE.),3/<G+>!2(C'A/*&;23AC+%FD%6-@&)-<4%##34(!,)-H
@r6445
NACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATA
+
&-+:+9D>F9&1+>@H?!1"$G<81E."$A-A'H',%)4;H/.++*G#(15*!7>2"F;"9(E0#4?C4;2");,/17H'==6F#,3-,C3;E+A"E"4<<&EB)/$+5$)%<
@r6446
GGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAA
+
/=A<:)+&/.3CD>;/6$+G4=0AC@$:HD%+=585%+F%=+9!,#C),%+$*-+,/9ED)$0=:)0HA0;>/$+0(96)@%"C!*,%3#>A=#;'>@82GC'H6
@r6447
AAGCAATGCTTTTTTATAATGCCAACTTTGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTG
+
3G21"611GD$H#>)-9E$E+D<)4%E-8"F3=(>@$7>4B3!#,3!%*,$!H!5@4&A03$>#56$5+>&#7>G%'A#31.3;CD1244'&9"F+5B#AE/%A%F)B)7E6-05;83)")1(";472/7CH;1&G).:!!B0'+>7(C)6;/+!;.&50$+H/)7!@D$C&$-&/2
@r6448
AGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGA
+
F.7:&E5=%$;%#<&<+(06E@(9'&8C&?(-'H,5&H<129.A)8FB%7=FG.@@@?5GDA>=#1*6@)90>$@C.2D
@r6449
ACTGCATAAACCATCGGGAGAGCAGGCGNTACGCANACTTTCGTC
+
G+<-910<*5-$@4C@-21*B<8)C(*=73H7/F@>*G<E&$#0@
@r6450
TCGCATATCAGGAAGCACACCCGATGGATANGCGACAGCAAGTTTTGGGTAGGCTGGTTTGTCAAACGCCTGCCCCTGCATCAGGACGTAGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGG
+
7:6."<>"9;CH>>>!0,@EA?+C6"+(88+42C@<$42H*F;8;+%4ED4-E55A!89H$1/.()42?9A&&@?D@0H3-:3>"9"0"2$G699A#;.G6+1GF1G?B**4.,7A:5D$?.0E!)33&?B*.!@>BC
@r6451
GCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCGCAGGA
+
6%.693BBD:-+*$!'%H%ED-18D?7,4159A>4>=,-00$B#FB%9F/>@$CF&5"-
@r6452
GGCAAACGTATACGGCNGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAANAGGGT
+
>@-+H8E3A,(")(3@<E$B"F)A@G,-"@*+?%/47@#40E<C@&)@-A%*722:BG=2
@r6453
TGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTNAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTG
+
#%('%,0!$4G/3<59?GF3=G*BB'@-&D-3:F$3*<36DF&#@2-"?E-8$EG41.!"3B..$=!H=/B7@D0%3$,E!!A+;$?&:?E/2A
@r6454
NNTGTCGCTGNCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAG
+
&%"+)'((&&))!)+)*)$)&(+($)+*!$$(+')#&"*(!%"#!!"*
@r6455
GACAAAATGCCGCAGCCTGTNAACCTGACTGTTCGATATATTCACT
+
;@:%?(G;G+"@#FB*83C0FA&AD3?$(4!/G>+D<9<,A777AD
@r6456
TAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTC
+
76F,#D:-4:E#27?/=/)*?(7.=77-/&2F#7$309D;H5+9$#2
@r6457
GCGCAACATGCTCTGCTTATAGCAATTNCAAGCGACTTAAATGTGCATATGGTGTTGTG
+
4B7=1+F6(F&%E33@!%+/(%D"'<.F9+FC9!$.E*<8?14F?HC,#7A$D2>9=>G
@r6458
CCCTAAACAATGAGTTGAAATTGCATATTGTTAATATTTANTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTG
+
&:!<?798CD<&%:=+'11B'=3E-D:?)D##F.2;<4?<@,)4F3%:)1F9C#2@2.?B8*B!$!:;H89@5F$!!:*G7)4=G%=:-5#3#'4'<&'1>$E0F8;1<3&;(:D//,&0
@r6459
GGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTNTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAA
+
H;).)A$=-.*.F><D29BG'1<?",*"1);%'A75>+'35(;@%0?2,DBBH:#<?-8C$;#>G"323=@/29'"3B6,$F<-B%@$"@"B$"H@FD89!,6*)2>AG&?!&@*
@r6460
GGACACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGG
+
E1HE2?H)'8)>2.$&1?!)$%&$$=$EB@8/A(H3#(>:->.8-:85E%69%DA1/D9/=
@r6461
GGTGATGCCGAGAACTTTATGANAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAANGAACCGGGATAACACG
+
6(5C<,&C-',/81#$($<!%11,G!9B;@DG$7C!"BCD87$/5$?G;!:%C37)"(FC;&24:=!)>06EF5/+88@,"()=,/=H&,6(A>/3E5.%H/FB:(;H
@r6462
NACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGC
+
"!CG@0;'E)'/35C+/#((G)H+G"1FD%?3*;%@F;97<E0.DA4=E$!2()4$70+8@/36%7">E+-$21>8/*B@7&<!@3$C#D(6@+!H:2;9"9H01CD2.=F($'4)1@@#2373G(+CE#&C4@D<.2*$1?
@r6463
TTNNTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTG
+
&&'!+*+%!%'$(!(#(+()(*!(""+%#*&*#"!"((!#)##!&('"!"#&%&"%+&!$$&#&!'&*+"'!)+"#+$+##")+!%'*$###%)+$!)$&*#!"()$(+$#$$!)
@r6464
TAAGCGCNGNGNTACAGCGGCACCGCCNTCGGGATTTTCACCACATCAATG
+
')"#))*!)#'"+#&#*&'""$$$(#&$(*(*#$!)(()"'+($#"+*"+(
@r6465
GCTNCTCTCTNCNAGCGCCTGCTGGGCTGAATGCCAACCNGAAAACGTACAGCGTGACGCTT
+
())!$&&'*!!)%+(*%(&)($$**+%#%%($)"&)"("%%*&$!*!!!!*$&(!#$$%+)+
@r6466
NNCAGCTCAGCAGTGCAACCAACAGCTCGTCTGAAACNCTTGNTGCAACGCCAAAGGCGGTTAA
+
%+)'&&+"'+("&"!')'#%+#)'+%')*(!$#&*)')+))%%%"&"''"'"'"")$()&%"(%
@r6467
GAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATT
+
CH"!&9E@-C>C8?6>@%7(<=!-$F=5A@(.$B&-078+;;>:A-%3C7C190."E)5/H2!,(?(!..D?015&3?F!H)-;8G8/4'E+:"':'%H:FE/>3,H+3"!ACA$9,3"(2A8*4<1<*H%;!B$F<
@r6468
NAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACCACCAAANACGATGTTATGCATATGCATTTCATCGGCCGAACAACGGTGAAGGTAGAAGCCAAGCTACCTGTACTTGGCGATATATTAAAGGTCTTAGGGGCAACAGATATTGAAGGGGAGCTTTTTGACTCATTGGATATAGTCAT
+
$H8G9!+#<(4<=?>5D2!5A%";02%<F3F!56>:!,3F5;;<#:2)32%#B*E69;E!!998//BH!2H@#-0A+&06=?&3.'C27BD00+.G3*537>(6@?2;DGB2'"<G;6%@1?C076->&?"<6G.+GEHC7H$E4">8903@083,&,H<>C#-/"/.,*E.$G=#)/H"FC4D(</+3!D&C.>96.'@-:52?
@r6469
GNCCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGAATCTCNCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTCAGACAGCAACCGGAAGNTTACTGTGGAAGACGCCATCAGAACCGGCGCGTTTCT
+
D8D91F7-1.F6@GA#D?:3C8*;.0G!*F-A?=7)=C51?:);4%D2;&>A$@**H(3H.:>34)-AGAG5!;3AE"B*45'E#8+@@5#<E6"=0EB6*?-H(H1G=.H,%>9-"CHA-E>4/5F<&CA)-(%H19
@r6470
AAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAG
+
;'2:>1G2<1@$*1;CE@!56BF.#!F2!<313B(#+"A6F@E>?)#+D//'%"<7%!;4B8$
@r6471
GTACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGC
+
.CCG*?+F9@?#;&$B*C.;?*C17**-7'7!1@=8@=%("8.CFH5(70.)+D:.&@"2=4%.$:7.B,3,8
@r6472
NCTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGATGCNTGGCACAAATTACGGCT
+
$<3=:;<5-ED4$8D7%"E%=$2G:$:$&35<=2B@-'&.?=!C!G*>?<)7AH<DG&4#+F.AE*2&$:>,)4>6#9B*''4'D$/>9*9D=D<558=93F@99H3)$@&&-A;:9/01,.%F+!DH$87@<-?.7F,@++8!F?<=4(28'B8,A.C%/!G=+/85!82;-B%?B:(*:-G(>"C)0E-GD#?>A(F;C@;$D7E>;0E1%
@r6473
ATCTGCACGGATGCTACACGAACCTGATNAACAAACTGGATACGATTGGATT
+
3F!+"*5*9@5+7D3:<'<$C2D;-'"30BE(B.9GD2A%94$8+B0@C4<+
@r6474
CTGCGGGGCTTTAAGGCGAGTTTTCGAATCTTAAGTTTATCNTTCTGTTTCTGCTCCTCTCGTCGTCGTTTCTTCTCTGCTGCTTTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCNCACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCNCGCTGGTTTAGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAG
+
?>G.'B>(='0+**$>%4;3@@9?/432,%!H--(5'%6D*C31EF?$+A&!BE</$;FA/#*F2'#.*</:5#0!,$9#5%CH#@G@9G//6>7,7+;>+3!*<=,'$",&&F/E?BH=G49B:B%D-F>$G6-&F0(0+(6,:4E4&&)H&:=$C3@8,/6&,EA,H9'H3;.7D<!;9?)G#1!?24+3.9?@%%C/2'CC:7G!@<!<=F>9+.GG3(="$.%$)=/,(C625D,108@F9=-"&>FGAE4'8$'.<6A67,DE#;*(<6?;(5?E'3==<2
@r6475
CACCATGCAANAAACTGCCCGGGTGATGGCAGAAATGGTCGATTCTGCCGACGGGCTACGCGCATTC
+
<&6A5*;&G:$."!06=F)=6',;:9?0"25<A1=8'1!?G'.6'E;D;#?./;6-D.>=!01::A3
@r6476
ACGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGNTGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCANTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTNTTTTGAGGGATAGCAANCCC
+
!EA,5+"4;2@E-*.HG?.5!/"6!1D#7/,>%GD1"7962B<)1-<(>*@F=(367-(?D6<EH"4">(658BA+:)H27$8EA?>1@;%331%4DGF6)%.C,#&"78!682D*E*"+<%$6)&$!'(2*B>0&H/?F@2243G,>2H-7'#.#-*)F,-C5#)@2!H)@$?**H8-50-!D-B4+8#&();&=7-00527.,?$5':%#F"27*D9.$A7$65/E;'-?27-(8C4.7:!5GG7,$1D08%1A?,<;@+/C=0)
@r6477
TCTGCACCGGCAGCNGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACNCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGA
+
0C6;?-@37:&$&E(%):=8;-HG?=#8<=HFG'H36,/61%%C>4<6"31:A)&);!?$@1*H8!E=!17.:B76E88$6%>'5.+A08H$>A!03F+>HD$+<3-5"@H&3EF%-?60-4550:B0>!07!9A)";$=E$.-:+4#BBD+&CH&6!E5H
@r6478
AACGCGGTCCGTTTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGACCACTTCCTCAAAACGGAACGTGCGGGACTTGTAGAACCTCANCGTGGTGCTGGTCTGGT
+
(,;G@@/97F24%.848=3FD$:<8%:G$1@-5-:FA3'(*.%,.E%/4?'H!>,HC4//=A+//=4(B.DC(F!?!21*;=2;,H3@A@;&7*"B5)FCE=2,"0
@r6479
GTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTAATTCCATCCTGTTCCTGAGACAATACAGCACCACCGCTGGCGGGTTTCCCCNTGATTGTCC
+
21,:5F$7=+7="2-4.+5@FF/(@<C@.F'B3#/<9,*B$6HC#G501C#?).!>8C*'-39?E$%B=D%%G/-&/D3B;$-;>/EG.C8G(B3)*;5274F99&C5G*)H34665:G=?),.0A&;+<CEE-?;#3A"AF$5ADEB@!CA=58A)"&7:'D=,F6F@-&6*>&A;)9='D;79"D
@r6480
AGCGNGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTG
+
$$%($+$(**((+$!$'*$&*#)'%+++'*(&!'("*(+$&'
@r6481
TTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAANACCCCCCGCGATTGGCACATTGGCAGCTNATCCGGAATCGCACTTACG
+
+0@185*8(D:9(0E$)68H%4=7&A9)H$8@(F>E9>G6!1FE!!*A$#54*,1+1>(7;9<@('A'H(E*6+C'$2=-F?<
@r6482
CCCTNATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATATGAAGGATTA
+
H<<+B;;595($GE-2@>&G+=-#@F/:!6?.C""'%=C99&(?.:#!(2CC;(17CG=+3>8G@99.=&A!4(27H$>'(E!-AF>*,*"H0?)/??%*2D
@r6483
AAAATGGCCGGTGGCNTGTCATGCAGCGTGTGGCTGGGAANAACCGT
+
8:"+0?$0#"(=#8#(>3"F$F%)<+G=(%*.H<<.7E)C(AC=9!C
@r6484
ATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTAT
+
5G,%-%H6#3(+67=F<BF0#<$;;%D/!F2"'+HFHCB/8=(?54.B/3?B'B)
@r6485
NCGANTTNAANCTGGTTACTGTTGCGCCTGTTAGCGTGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGNATAATTGCCTCTT
+
$*%"%'&$'&!+*(+!'!+(!&%()&"!#$#+''#"!*!*+#'+)$&%'!&+$$"("!!+%(&()"$!%!!#!$)%'''**"%'(#(((%$%&$)(
@r6486
GATGACCGTACTCAAACATCGGGTTGAGTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCG
+
/!8$B7-$-#$#A9/?06'2G'$C,:1$.<).%C$<*5G07&H#'=5,D*3(/<&B="E/FF2,&H//(
@r6487
GCGCCTGAAGGAACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGACCAGCTTCGCGGGAACTGGATGGCAGGCCTGAAGTCCGG
+
A<$9%!0#=BH);$4E$+=H7566+2*7?-07%E##FG4?DB81-/'E@4+5)'')BBDA*>+?3?:A?()5)02000A@C%.-BG=(HF0E#),&#/;)'7&?H<2@(8CE?"0&A$)8>$/
@r6488
AGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGC
+
>/+<06?.%76HD>&5DC$58457''?!7>*-.AFH%3;BG%@1=380GC3;;'FE!*.(5GD.;(95FG)'=61G%3E&,<(&',=#*':H:E9(F51"B!$
@r6489
AGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGG
+
%%G:$63(7&B)37(&?%#9C:DA03798/.H=/3.31>&36"%B%;'8G%48H:<(+6A8,)FH-<9!-!D&0/0F9G+'0F!C>3>=*<&68G0?*'2=%#2EH+F.H>,29,<;4B
@r6490
GACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCANACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGNATCAGGTACGGATTNCTGGGCGGGACGTCAGCACGT
+
2AF'2&EG$*@4?6*!;;6%&4@&:>4?'5>$#E$0+6*C99;17-8%>@@FC'*;%:@%:<="G08"817((?468<.C<3$=%-,*6?861:''.G"?.26H"GB")2BF??';5'1-#9=-
@r6491
TTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATC
+
/G0)H!F+74'BA4*)H0+;?+?F2HG35,BEB5(5A-+(9F#3,<"$09:>/84A3CFG/5;0#H9";B?;@-890;5.-4C%):9)H
@r6492
ATGNTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAANTGATGGCAGCAAATACCGAAATATTTGGG
+
@*E+G,!./2D:3!6*C32A;1A>>6C$!(E&C(E5+F!5C17=CE)<#9-=<D0#8;.@E#3/-?2!A-8CBGC!!
@r6493
ATATCATGCCGTTAATATGTTGCCATCCGTGGCAANCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTC
+
(F3C-B3&7,;<,D0A.9B',6F.130=#+@#F9"31(":E"?&H4-!+!;0D2=08=>/3G159CA&?<H5G!(>5"EC0C<E+-9/
@r6494
CATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGA
+
.8=>3?(!#**)!F>:.*8*GEA;H-E);#'A9'+8/<*.$$G',(F&
@r6495
CGAGAATTAACCGTGGTGAGGCGATCCCTGAANCAGTAAAACAACTTCCTGTCATGGGCGGTACACCTCTAAATCGTGCANAGGCTCTG
+
D79:'&/9#,"F(5/=76G$3&G,41*4@:D=*;(AAF-93C&(!C:'82+6(#B2:'+/?<.F5A5=,;00-)FH*648-B'0;E+F&
@r6496
CGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATANCG
+
F#'4&;3(9,92;5#6>/#=:$@8F3#&%AC/*5B"FB,)+,.6#,@<!?)<+H
@r6497
TCCTTAGATGAAAGCATTGACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAANCTATTCNGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATT
+
6B#*"=8/"::+D0C#3C2D?C7;>9=-';66BC)#!4/A::D@);634-6%;B+8/H-"@FE@ECG:@F1*"=B#5*!2+C3(68<%/%):=)"<G"31=0"*2=3'E*'=D%=-;4$!
@r6498
CGTATGGCTACGACTATTGTTAAAAANCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAA
+
E31C9#3+"6%4+"+"G'1C,68A6C:*E",F@<)%@"+27B1H(1-6>:,/9<@:920A.$"*7H65>E1)9*#6D7
@r6499
AGCTATATCTTCTGCACGTTTTGCCGAATTTTTTGCACGTATTGCCGCTGCTTCTGCCGCACTTTTGCTC
+
BF?0-".2>@0F"+#5C.@D)+3F?!"+(A)96&-/2(2H1@+.FG@8/'214#!>G9*''(9B"6##*?
@r6500
GGCATTGCACCACCANAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGT
+
C21D-#*=2D.AG!(4??-%B<5<9EHA!G)E:)"+1*9)<7A8&17<+%<'@2+3.=B7<
@r6501
GTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAACGGCAACATCATCACGCAGAGCATNATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCANCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCTCGCTGGGCTTTG
+
?A-@4+4DHE(#*1?D!A%4H#!+3;/!B1:'(6@"-7+8<8"/?5A&$0<$E=9F@>21%-!HHB'H4C@C)0'%D$**$9H-?9E0*,?"#.C5.<GB(=;.'99((,=0G0@;:?<<@43!=2;19HEF08($1(2*$+@!6"@+<#77)1D!!?$(H584;-2H$11<1'HG/(5-8B7$+7+56#9%09!@:D-EE?C35!.:G3";=!4@FB<29EEB:+0(B"0;<D720*0">@3H)+;&DG1/?<?8?9;>+%:34;&?"9;/*5
@r6502
TTTATCTTACTGTCTTTGATGAGCATGGTGAGAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAATANGAAGTAAGCACTTATACATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTTTTTCCTTAGGT
+
-:95;-<"&<:!91%1@25<0"5B)B7:4C<GCF#33;@A-$11=:):50*(1=,C>9A)#$D+F56@@;.)HF:F-GC.=E@*A0FA<8H<>/:8(3'<0('#:1?4##$*02#7D?<<'+7&H1')%3GC:<,"5;3@CH$!:C3@/
@r6503
TATCCCCGCCCGACAACGNCNGCAATGTACCCGGTTTCACTTGAAAATAGCCNACCGTAAACGTACCATGTCCACCTTCCGCACNGGCCGGAGTGACTGTCACCGCAAGTGCGGCAAAGACAGCAACGGCAATANACACATTACGCATCGTTCACNTCTCACTGTTTTATAATAAAACGCCCGTTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCATAACCTG
+
D67!?E:!$=)?F#A372B"8/5=7<.9>.,4(A8"B)4"DCGA9(A%".9!:,?')5=0(@)EH.@GH';8?C2(.&F,)#22%8?(#<&,68;13)EE.CC";#5&2,%?H4.>HGA%A3;0!D)1+C&F4B,<G8208+;*?7<@;C&>!?DD?6C0181@<HD#4;03&!>@;?GC5>+@)!'5)B9<*7.>1$'5('#($);*B6+?#?6*=?+.5D';=*E37'36D)C*;A>C5.!%ED$.!,?!;20$D
@r6504
NGAANATGCTCGACACGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGNAGGCGATGTATGCCGACNCTNTTGAGAGTGAGCNGGATACGCAGTCAGCGAT
+
"'(("')+"#*$*'(#(&#'!!%%%"")#(!&'("&*&+)%+*!''$("&&("*!"%*'%%%*#)+!"'"$*'#&*++$'&!''#&)&'&#)')"#'"*!!&#
@r6505
CACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCC
+
.:8;B?FF=)9D0A=%-0-A.?:(%?:"9424+@A/HD<F546*HA%=27)=>6F4=(
@r6506
TTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAANCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTA
+
?-%B'!G-"**F1A="11F&C#6A;2(7-;+)"!4B56%:828'1>&1(0B1B3E"G?+44;9D=57"7H);DF8)/&!,2$?&'!0839=E5*!B#%<?+2"?8,=F9E#B18.H64
@r6507
TGCACATTTAAGTCGCTTGCAATTGCTATAAGCAGAGCATGTTGCCCNAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTGTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGA
+
9C7+*"9"H#@;0H9!(H?"!A:#5>)35A)28,A?'G*)7%(:>.+/,!0;H29574F:"G-)5>=>53$#=9B(3>=5E"D7@,).9168!>1#9H3<;56&/@6HEF8E468'%;$;1@/3"A"$8HF*!1(B)?BGF@(H5?*<&';3C4+9$9$9EC?:"1*D4#!C'G;D6=-=;*&12#4*4$:%86:!!C/>A9!-G/E!"!+C/.0?.!#4%9%"+0!$>(<@"(-DG)7D7FD%3,&*)'!D$@0+<1H8,"/;%)?1#)E<F+?F-(
@r6508
TTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGNATGTCGAGCAAAGCAANACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATNAAGGAAACACTT
+
0,)<!6"$':3)&%GH53174!#>'&-#65;8:!232;D%F)!<D"<0)$$,$1F3!<C4,>6"32FD44F3F23<%1+D!99)@*AC28F5%'"-7E&GCAG4.?&$4*C4-%(4+$=;8C6-<C7;;G3*@=+6/9D5:>/7(2/
@r6509
GCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCA
+
*C0H%!9F5+(*$E="<;<&'9((#BA36*<@"6328B)B3?0$#=4D*.'7F-!@0AD;
@r6510
TTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAA
+
4@9+@D0@$)7D@5A%+F4A)&0.@EDE4F*3=<,<>3:/G"AE"%?%<@H,2;90C,'=:5<
@r6511
TNATGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAAACTTTTTCCCGATGGAANGGAAAGCATATATTATTCCCTATTGAGGATATTTACNGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTA
+
#'+*$*%'('#**+'')&'''#$()'(*&$*#(&(''""&*(")##*!)&(#+"&+)++"*%'*'!+$!#"&&&%+'&%#'("$('*(+"&$$")((&&'&')#%%''("%"((!%!"%)$$#&#+$+!"*&)$!)"+%$)+&($%'(&+$"%'*&"()$**"$)+#(!*%()*+)%!"'(&*+&""'$%")"%)+%*'")(!&(!*#$)+*'##+)&!+
@r6512
ATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAA
+
'/=.-2-9A-4=7#:H$F52@=%'*D?"-%C$?8C:(0;8<(1.,D7+<;++
@r6513
NNNNTNGCCGNNTTTTANNNGANNNGATAANNCTNATTNNGNANCNNGGTTTGATCTNNNTTATTCANNNTGANCAA
+
!!!"$$"$#$"$##$!$""#$$##"##$#"$!"$"!$##!"!"#$"##$"$$!!$$$$!!"$##$$#$"!""""!#!
@r6514
NTTTATNCAGCAGCAGNCATCCTCGGCAAACTCTTTCCATGCCGCTTCNACCTCGCGGGAAAAGGCACGGGC
+
"(%&&%+"#!)$+*#"#)*$+(!$'*'("%##))''%&*""'!+$*)%#*($&()$$#"+##%"'%"&(%"'
@r6515
GAGGATGTGCTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGC
+
6H+E2:=6.2=35C4#<>2A'#*3H?H*>6($4(E%-C)/:,H4(H*A%!#"2
@r6516
TACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCNGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCANATATAGCCTGGTGGTTCNGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTA
+
67,(52:0!*2:@#0*3!2EC@)/>65'.&CB&@@0<A1<67'56#4$7<)%'*571="%1>19#C4'<>)-"-#;<!C"BEF$'9A8:+>*:79B@>03*D5700?94%DA*9FH**1=?#A@%2;(19--6/>?@0/)D*>=;85(<.39824&,>3GB)
@r6517
AGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGAACAGCACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGTTTTACCACTTTCCTGACAGNGACAGACTGCGTGTTGGNTCTGTCACAGACTAAATAGTTTGAATGTTTAGCGGTTATGGNGATCAGTCAACCACCAAGGAATAATCCTTCATATTATTATCGTGCTNCACCAA
+
D200<,&;:G0138+3G;2#$"2H818?G&0*G+9F('%4267;**-E/86E4;;/9F-766825)+?990+8%#)1E3(B=0=./.D'753:%&5$HH+1*?C.*1E>)F$/1#E=F75C:93<%!<,E:;=&++!H64H=9(##*>(&&<&:(0G;4==3EE5+53@CF;!=9"B>+DH>'F;"/D,)"C%<(#4F-4<(2F#H%DG!D;<,F;F"993%)G"%!@H/&/$>16:C#0AC8E)B:0@?@=/!13,E
@r6518
NAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGT
+
$H*2,%"#5DG0C!-HE!70",/F?G?=5-(&@F47HF*&;>.E>'0/C-E'*H3!>*A#$.&G#@/F18F6-%:3!:-
@r6519
ACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTAGTCNTTGTGGGATGCCTACCGCAAGNAGCT
+
1'3B9+3?':$.+B;6+:B195.:,8D&:G%>'G*&FHACD0F:)+1/CFD/G:"C%)%.*B@A??9G=43?F($?@'<+B
@r6520
NNCTTNTGGANACCACCACTTATTATCGCAGTCCGTTGATTCAGAGCTNTCTTATGAAACCATTCTANAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGAACAGAGATGAAAGTAAAGTACAATGAAAAAACTACCTCNTCCAGCGAGAACTTCTAGCGAAATGCTTAATAAATGCT
+
(&*$%!+%"$"##%&*'*%)$*"*+!"!((""$&*)((&")+*)$%&#"'#'!&$'(%#*&#)#(&$$*))%$$$+'*!#($%+("#+&#)++**)*'%%+#!*%$*))$"")*##")(*))"#""#"'''("+''++&'#)%(%&#&$$$&++!$%'+%+'%$%!%+!'+)'*#%&))$(%#'*($+)#!+$**&!$"'"(*'%
@r6521
GNTAGTNATANTGCTAGCTNNATCAGNNACCTTCCCGAGGGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATNTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGT
+
($&((*(%(!!)%%)*%*""#'&$'&"!)!!(+("$)(#(#&+$+&%$))(*('##%#+'$*(#*"#(*%'&++'*"++*+(%%&)$&$*$%"(("'!#$')$&!"&+#+*#'%%()&!#'"*!!+!(!('(("*"!")+*&%!('(!'!%#!"#(%'"&#'$(''!(!#*(#*(&)&!!+"('($'#('$#($)!'+""!!
@r6522
TTCCNATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTT
+
102B%0+:*8.B25<5BH?A;);3+A)&'@1B$@+68DG48C/6GD/C+-&(#&>#8<:.D.+'!2$6%+,5?C:+D#H/,8<AE3D7.DHG:89>CA069DGG+@1#;0#!
@r6523
CGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCG
+
&4"7=%(A/<'($@C>>7<!-E@&B<);(4%/9<D<<40=4!>D3&3GH2;?&)!A&>
@r6524
TGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGT
+
#@*<D.%/4&D37*'G7CE?5(81EGC/,;BD*ADG17*7+;;7"1#)-75&=-A!*?)-?CC>5/*>6.G5<3A=
@r6525
NTGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAAT
+
&F-$@!!D=*@&8%7.,21F.15)=D).2A)?$-,*2'F/(>:*=G.C2#2.?)>-&=;8>#$D!0/9-8G$73@A7'"440HE;E,A?=$$?'*/%<2
@r6526
GTCAGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGG
+
7'5!-7'9(&B3#7#5B"9;08&1,?/&/FG2D?;#65%;$&82C+6,727H9D"6CH@/5.<9H4#
@r6527
AGCGATGTCATGCCGTCCGGCCCCAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTTCTGTACTGTT
+
F4"H<,0H3;&?2@3(<H;,C,74@?'B'7*B"%+%)"F$AD'H646,C'%$D;24!*8;"&#1E5<&D@!/@*H7$C66%5?;;E*4",9?845*/"1G2A38?+$%?<626<@AG'&?3*C72DD#&*+?0B-BDF=,1D:7&0:?<-;?EF(&9EF+D;606.+31$--A,1@?D5#>D/:E
@r6528
ATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCAGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAACTCCCGGGAGGTAAACGGGCATT
+
B?F"&0C'+"%/EF-,%:-/51&%67#%68C!&(?H@"'G.=2';H8#'".6C/<>2<D9%.30G)8G8,225/30*F46798"":/$<E51G/.2#*A@B6)7C&#,.F=D6%8C?/@@4,"DGG%2814/$:/5"2,D6)4%);%079,#C9)=F;@&;5#;8:,9$+A7'21F"47+?,0#!D+3>.&E)/A54H-0(A&:,=G<<#=(,<
@r6529
CATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGCAGGAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAA
+
62D+-/-1,#55927A(@@8F#5-!F8;C$0AD:6-G.8<E-,&&)E,6<'#0&3"@&H?FG;#:12+(-4B;+F>,)8$!<0,H757"5&4",%)B59,!7=":("8(-$6).&:33+'>(*"7:'GE1,
@r6530
ATCAAGCTGGNTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCTTCGTATTCCC
+
4-C4'#5H+?.&,3)F&.9,9#7,A/A9&189@/):1DD"6*'.F*E@C/1A'C4"8"F/G'&/A,A1(6B("<B!+6)%0)#=6@%1BC>3%'"@@>B.(<H%F-@"%$G>3DH0A
@r6531
NTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAATTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGNCTGGGGATTTGACGCAGACCTNTTCCATGAATTGGTAACACCATCGATTG
+
!H80:!5E%0$'3%G7134%)<?5((8#2.;*@#3=?D)"&%9G-&)B0F!@08E)?7=E)4/<<>34B4/D%-5)&=3FD3+D0A2AAD>?AA!%.7285CH-!7D;/)BD@'7&A=4G2;@F"@H)D'&30D$E(D'-(G6HGA)":3.A:0(>6;.:-/6H=)%B8'-:>8"!0*>#1F-A1:/;H'=+>-1-12B-A@'!>H8@4#=<21<"4(.6'@+9
@r6532
CCGTCAGCTCGACTTTTTCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGG
+
(FD;F(GG)*#9/23&G56D<2?<C(=-:*,GH?.*8H#D9-E#D=!A.D/)9358E=%852$E*92G%H<2+:+E:+;=5(FH9=$!./"7>(1"=<:226;/H%!%HHG-<&5)C$H9E0@12?2*.69DC2510%-=<5/:.182-F98,*3>1HC>*6D3/F%#-1
@r6533
GCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATG
+
.>((-3-(4(BE8>.BA@!215*.7>;#H?570*..4*394*HDD!(FC<9H,B@?):/=%B9$G6#CH8&+7G8&*("B78F7;F)8(G:/175;,
@r6534
GCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTA
+
?#(37<1;32B)1+%0CD0&B9.!:90D#5EF>8-=/C4!9G#1;.(@$&:!>E!.G2$#4AEAG(.
@r6535
GCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGNAAGAGCTTTAGGCAGAATTTCTTTGTCGTAATCGAGATTAAAGAACCAGCCA
+
,.&!H9(1D;6"--E(@9&0D5/"?C:./87-E:@&)3?*A46$%:EFD2.C;''=5!F)5*8!2,@#;-?E(<EGFG$B*$54-<0;"?07F)>8'<)=0:(&D(%#%C,B-3
@r6536
AATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGTCCACGGATTAAGGCCGTACTGGTTGGCAACGANCAGTAATGCGATGAACTGCGCATCGC
+
%E=HH?.-.6;>2:?7HD!F+1?&C%@?8&#*38A14*7!E@"B>#(!3$A2&"B+1D3?&-G<G,("+=9:47H9!&(8-C9"73;5C-?3-2%2
@r6537
GAATGTATAACTGCTGTNACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGNTGTGATTTCGCCAACATCATTCGACTCTTTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACA
+
/G,F6%&"+>EEA3"#1>'$1BHA'#4D.C16#F8H6;<&$+A'&%/3.E2&=B69>!C('=B>"+/<.($&;9F,-19.F9H,&F523H>H4?*#.;GA(!>9#!9='D3E/824A)68C:#:4-?#,&;1$$1/(,%9AA/2F>4350")E-C50'$$7.:'!A
@r6538
NCANTGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTANTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACC
+
%#'$'88).@BF*5,?3/"$$&"A+C41>C?!+=4$/:859G>36"<?=C5#B>1#)/G:BG$,'@0)(238,=5"$E5#D)1(!$'#=0864D#!BHC18D60,6988>@9A6%C1-5A(H91$/$*;0GCA$>.+B(=,H(6!#/3%8C=,D--&7D?H&+@4)?,#$5;.:E16)'(
@r6539
GCNGTAACCAAGACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAGT
+
*(&()(&*$&$'(*(#($+#"!##'("$*!!'%*&')&"!*"(+)&*$%+!%$
@r6540
ACGTATGACCCGACCGACGATNTCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTT
+
(@+6@!2*F'6'32&'3@G;;2,@><-"9EH.'G06:/')89'HF)C"$9H,8H+(FAA/7;!2-97GAG63%C":;G9!8)@;6A.5E8>0:4C
@r6541
GAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTAT
+
/$/@88.D%E,-9H<>89&)?G'797H'-.G>;96-6->'+*7A?0-.0!),-"0*&E&&8!%<A;=G#:E&>'/+;G#5)GC(@4.'2<4=B-4.
@r6542
NGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAA
+
%-73.0:<0H!(=?!2F-*30A"0HD.@172,2.+?(+30+(B(&=98B"07$8"D
@r6543
TGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACG
+
@,&0<;0?2..E.(+@.*A)G&$>"*.7"'#03CC8A8&-8B?<,>FC%:61);HE'*,+A43?1H
@r6544
CTGCAGAGCAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCNGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCNGGTG
+
+'C1H5>9D#E+(6"7F;%ADE5:(*-51GG6H"%%A./C5!'%D;"5"G$8@3#(/:'%'#-A&2=F5>5A92-$:.;G0B,6&3$)(,<)+.2*@(F4:#0,G"3/6CG(62,3<%?5
@r6545
GGAGATATTTTAACAGAGCATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGA
+
7<D<5A1E;A!D/FAC.E3+%*65;(E):700%4.5CH::$E<#*9?E4E8$G*1,B++*-4;3E4.G'0&/-&0'-*%#76(!9":8FBFDB("#AB9>8@@39><A04$6-A?
@r6546
TTGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCG
+
%!++&"+)#%!!#&%#%++$)&"+*#+(#*%#)%"%$()%&$(%&
@r6547
TTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCNCTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCT
+
)-H0%G(H@"-+G06)D(@=F07B#>D"A09'?A:G9@9,.H@E$:@;?1<'2$*!3'$05<9;707EED9$A3"%42'B>2FC6(1/
@r6548
TTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGTACTGGCGCTTCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGANGTGGGATCAGCGCAGNCNGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATGCACTTCACGCCACGCGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTG
+
.2D>-19/'=F:/@H>(@F#C2/0;>,"4(')C0H8%3#E2.'3+.=<)83G))#)H7(15;+3A5F;=A<??36)($*(6"**9$%)C1>0A'50),",5"A!'&)B+(;3GBAD%>)4!*3<7CG''BH,.>@6%/4*+=A,!=76<$;F<80/+&,(6F7@59'78:&)F-485H$5:-;8CHB#?G,(#E?84"6#9!"=%4?<?>GBG%G<55E>78@EG.)+G@:2*=15*C+(/;*/&?666G?FA*D%("!GAD)F;17H$'<4*67<),9'AE>>9D4"#1*G(E#0.C(78.-HA7%#,9G?E0,/@.)#100=9-=?+**)>(>B0"G*'9)CB>6HG#<$)>?"+&7?5D+0%)52&%.25(:
@r6549
GTATCGNTCCGGATTGCAGCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTAAGATAACCGCCACG
+
+106>*(D-@B,+$@<0":E4@D5E8:;/)?1@('G'>($*B*;"(,:E38<E6(%8:<#.5C4$);9C2212$3766
@r6550
GCAACCGCNGCAAACTCACCATTACCGGATACAACCTGAATGTTG
+
2,4@"14@G4:7#63.@2"8D&7E7/A39)%*6?<+.=2%!C5.,
@r6551
NGTCNTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTTACATCCTCCTGCCGTTTTGCCCGTGCATATCG
+
%'&%!')*(*+&##+!"%#%""!*(+"&%&#'%(&'#)&"!&&*%*!"!&%!($(*&&&))"&%$!(%#!&)#*%'#!(+$%$'()'%*#('"!%)+'+("*'()#)$%*)'&*
@r6552
GGAAGCTGCACGACCGGCAATTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGC
+
B?:#5G1=2<%3%'";A;D%='+!C;>A>%/DDH'&@@H4G0.!6C24(7+&"AB9+-13,5(E"&6$5;99@',2B(H*;ED=B.8EGD.C+
@r6553
CTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACC
+
;"0?'69.+>D9<<11>7<D7&(2D8<#+C!<5/))&&,#.&)),
@r6554
AAAAACCACCTCGCAGTATCTGGCCTCGGTGGTGATGGGTAACCTGCCGCCGCGCCCGTTTAATATCCGG
+
$H-7'9(A(32<E-/+3DAF5D?<B3;+!%G,A3?D1*".@=.%,#*$E331+7D@3#(B5.97%<5%G1
@r6555
TGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGANAACAGGA
+
<"0H7<(C(1+%'7$C/"3+,&A$D1&<C$/)6&(A784$$DGC#5*)(;2)HAC=
@r6556
NGTNCNNACCTGNTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCGAATCTNCATACAGAAAGATTTGAAGTAATATTTTAACCGCT
+
"*&"*"$!&%&!!+$*+)!"+#%''$'(&%!('&#'*&)'%$''+'#)!"$*!!*#(%*"%++!+)+(+$('$'*&$*$"()##(&&&)$+%+%%"#)#+))$+()#&
@r6557
ATTGAAGGGCAAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGNATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGNGACAGATT
+
11%@672=6+E&!$B,F%36?("'*9=?4'**'>FBA2#&81D7C-/1$.E4;-)A-B<@@E0%F>)C*G(>(%#A@>(@.F=0&A+4/C4G@3->209D60>&;1(!20>,G5:0*A/:%B9A%61A%;4&2.%$/=(
@r6558
ATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATNAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGA
+
C+B94B7:8*CBE5E7;2=BE41EE$EB70.#,F%"969<+C!..B.H2E((+*&<7A3F"!>$7H;""-B#9A6,*<<@=%$79$-(;#A2F
@r6559
GCTTCATCCGCGATATCGCAGTCGGNGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAANCTGGTAAAGGAAAGGGCCAGGCTGAA
+
B(F@2#/3$"?FF(?B+%9&$(8B)?!70;7)6,<E(*F#!E@;/E)&H?&08#+06;36/=59,F@.$&:B?6A9A/@(!6@54;.90
@r6560
GTATCAGAACATGNGGGCCAATGCGCTTACTGATGCGGAATTACGCCG
+
3=5;??2=*A>;/E::8<5?D@'=!=C89;G@%,0.36=@(G'48D4;
@r6561
GCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGTCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCNCCGGAATGGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGAGATCCCCATTAAAGGCGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAA
+
=2+4E!98C.(4C$!=,<E*'.*-6??4AH>@CG;#7909",50+455)6DCA2!5;!5*<;2>-:'@-=;93@><D8.8,A>/47B:A%1#A+8CH1!<D%%;#0AD6:,A.B<0<&0E6>8$A&':-<+'<+@?#><-@-9H$?*$@7?63.<&0,F7<>CA.&%E44B"5:36*4(@(/@&;./45/&1<#05H+G;>#43'+&42.H=,1E346;*F)"&2@204>D20=>5H5E59.A/52D52GA?1?/*:?!)H(%0B+5;&E36/-<@(D)%8<:!0)>:@=,0?7CF#
@r6562
GGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAG
+
H.5E*"?")5865)!85$B(-(*$B7-%%!'=>78@DE=F&0(<AG)B2677@@/"9A.+>44!D?%%)8'12)<>4:<,<=>FB:1%'AD:734(;%4?'#C>8HC#1E
@r6563
CCAGCCATCAACGCCCACCACCGGAACGATGCCATTCTGCTTATCAGGAAAGGCGTAAATTTCTTTCGGCCACGGATTAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGNTGAACTGCGCATTGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTCCTGTGGGTCGACAGAATCCATGCCGACACGTTCAGCCAGCTTCCCAGCCAGCGTTGCGAGTGCAGTACTCATTCGTTTTATACCTCTGAATCAATA
+
.!4;=&%A=,=$3(B%@&9FCB)-*+6);(A%B<F+?%?.#0@&H,3>+&;3@#D$26FA':/F1,8&3)#!H.',/'G"G4:HB8>1H,B.=@<)%H.%"=<D:,+$+6-#902=B>-8#6E,==5(3*@&/:'8@C7AC!2-F8-><,8!?BC#?);6+07G?HF8!,49/(G?1'.&?<&CDH%,10>/3$&4&BE%$323.0"=73<C==@A)>D'9F1C?0;:=@'(*C28/0%ADD*30,F$8D'9,D7!-E3@H'#//5*G24
@r6564
TCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTAT
+
8+18."%G32903,E4H7<A&G&3.)3=A+;><D$6+DGF@1B'"A@A4F>%(3-;1>0%A@0C94CC<
@r6565
NTCTTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAAT
+
"%((+%$''&%*%%+#$+'"+$'&+!"#*+)'"!$*(&*'!(*#')&#$")+
@r6566
AACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTNACAAAAAAACAACAGCATAAATAACCCCGC
+
FG<?'?5E-E+/F*9&6*2A<0*"1/70(3:?*(/?.)<(F35;G0"H797)#.%<(8#8FAF/2!-A=7E60A6-'7H,F*;E&5)=66)%8-=-1,H.0C@F$'F51@,#D+<5)99%+"FG>GB,D(H%';G.@2'*51!1&$A.8130G*AD854!9<+=,<'1+.-2A.,4+1H0"=0@42.#F3/@"?2C@
@r6567
NTAGCGTTNTGCTGATGTGCTGGANATCAAATTTCAAANGTTAGTTTTTTCATGACTTCCCTCTCCACCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATACCACCAATACCCGTTTCATCGCGGCACTCTGGCGACNCTCCTTAAAAAACAGCTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTA
+
&&("$#&%!$%+#%&))$($*"+&'("++&$!')&##!!)&'#+$(!(*')')%)"+(+)%%"+*')#'+)+&+&+&$!&+)"+*"%#+%!$%($)#!))(''+'#(("))&'"+%##("$(+!*'&%(+!$+(+++$"!!("))%'#&'$())*%&%*+"+#&'&!#'*++&#$+$"%$&*$*%)&&"&+(")*(+'*!%*%%$*'*#"&)!$'*%&'$"&*#)**#%$!#+!'
@r6568
TTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGT
+
12D3#C4"1F=&,7D%5?6,/*%/HA1G7+*'F6C!;-<9#3/4=F<"<!F@-F/3G.'73+>><$=<47CHA!<A':90%D#
@r6569
GCAGCATGAAAAAAATGCTACTCGCTACTGCGCTGGCCCTGCTTATTACAGGATGT
+
+&7/634.F/B!HB="6>C9?A(>9)&(91>(**C+3!8G=G!F"::?@(8<6-.:
@r6570
ACGACACGGGCAGACTTCACCACATTCACCTNACGGATGTAGTCGCTGCCNATCGCATTCATGA
+
#A?!6&$0H8@8(7E>&:E7!05&@&'2$7;B'B(*"+>"6;:#)E@(1ECD16->0)>-/;#$
@r6571
ATTGGAGGCCATCCTTCCTGACCATTTCCATCATTCCAGTCGAACTCACACACNACACCATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTGAAGTTTTTCCTCTGTCATTACGTCATGGTCGATTTCAATTTCTATTGATGCTTTCCAGTCGTAATCAATGAAGTNTTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCC
+
.D-<H6)*B8!G8ED,<$-(@B7%42E3A2;F#0C'68H7EG<.8@H@=&/.5-(&15(8>26-4<-!%+=)926*&B0+)?6E*<-8@2EF+";,5)+/3FC5,8=#A04-/2"<!FF1A#GB3$BD4+!3F7B5H44<$>=-H7299$8,38A8&B?60.0)5.8#>:>+A"D)#G&?((1"&:5?)92,;:/3--.(B<46:0GH/..*A!47</#AC%%)6C$E&!<%4<(+!E+81=5"#*&=B5:.!>&7*!+7'F!966#*(&#<G2,=%A-;,<)C4:*<3+8*D#,"7?&&D#;A>6%#/1G)&2#-9:?G;-9,&,F9&0./?AE//5"=+)?@>
@r6572
CGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGNTAATGTCCGGTGTCAT
+
*&$A?*A4?>G%*;@C?%/,'-/G6.'EA0D57#/1'!,@8!06/-G**5D5+(&:4,":C,.E%7.68?"5,!>*&,5*,8/8)>:4.2,
@r6573
TGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGNCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGT
+
1#@E00H3.)D<.D%02!".;!F:3+H,=;*"F,-%';??:H*$A9%83)*4/+,(=DH.",0@##+E;BEC'3?7<4F9432GA>5->E@7%@#=4)535883/E2#E):)&,'@G/(F?D2@H85%66
@r6574
GGCAACTCATGCAATTATTGTGAGCAATACACACGCGCTTCNAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGANTGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACNGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGATGGTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAA
+
2$GD4-#=1A0+;D0844'@CH1,;41$7H"(&1<6-'%>G&6',E+8%/1$)0C.D/E8FCA&+#);-H6=5%#)":#49%"??-G$6)86H49F5DC75=G5.>!//=7*$--!@149'1C>)F,GG?>4&0".$F>"/-=,0"A8"%6=+(?A6<15$''+!/C>5B!-<,3**C39H@2C0?-#(E<H80E"*;-;.)>5(:1GE+22@*&9/7D:BD+D==5;?8A(8-/-D0<2+5<4@?+:0
@r6575
CNNNNANNNCTNNNGNNCNNNGANNNNANNANNNCNCCGNNNNTCNNGTNNNGANGTACNCANNTANTNTCNCGTGACTGNNCCNAGCGNTCTNNNATGCGNNCNANCCNACNGNGGNANNNGNCC
+
$!"!#$$!#"$#!##$$#!!#$"!#$$#"!##$!!!$$$!#$!$!""##"$"#$"##"!##$#$!$#"!$""$$$!##$#""!$""#$$!!#$"!##!$#!#"#$#$$$!!!#$"#$$$!!$"#"$
@r6576
NTCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTT
+
"F5$96C>(,00(*")02@E8)..#A5*,!F337;,';@#G-2#B2@AH:9F%<27*"$F&H:'D>
@r6577
ATGTATTGTCTCAGGAACAGGNTGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGNTACGGATTTGGGGACGAAAA
+
!<&F(E(F65?7@@*F%1/8:>6@=B%!<G@=*2<F64==-H%1-#:2F<7<"%*@G2BFE)&&'@%#E.B6/?%-5D%A>
@r6578
ATCTCGTGNTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCG
+
:<B!;D+::/-#!1!EECC;9<D579/2F1;$.A!6#,>1)!&
@r6579
AAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCANTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGC
+
)'7,%,3:E$AE*G$-H9BG6$B?-*;.($),0A@"%G6$-&@77<?A49:%H*F',)919B6D6'3D$>6&D;7'(.,)BG<B-*,5-<EF?6!EB2B:2>(%.'8?001)&193<&?49@+5+E(0)24B%H;B0*
@r6580
ATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCNACAGGTCAGTTATTTACCTA
+
.7D&;@17"5!=GD5C&'/$8/7><!1>-".$@$5B:GH$9@FD>28#2*5>;HH"C1+-6>"-04%9B7'HH<&:H:2!!6";F>-$DBA,9+
@r6581
TTACGTTACATTCATGGCTTGATCGCTACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCNAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTNAAGACATCACCACAAAAGAAATTGCGGCAATCCTCAATGGATAAATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTGAAGGCC
+
.2.EB$-B$5:)D(C1.@C4"@,+%:*743)G13C12;.>;>;"1@C7-4>B<A6)31<,!G=GG%'@/3:'+.5>>$D:=(*=D4<+BBC?<%/9<!05#1".A3E09/@",;*:>C>),";@0@"4:B2G$'C+)2DH-8F?)8BA%3*7A!>F+,A*$9;/1;9A;+7,9C%A,C'(=E752C:H>:,A<;:<*6("H"B-D*0;%:G?$:7C,(-$84)--,FF+=@4"G@")1-$76E;!#<4*0(56,
@r6582
CTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGC
+
G?1489EG16'%A(G69#H?$$/<7<F$-@5-F4$0CH(;.A<EF3:,A/!>
@r6583
ATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGTCAGCGAGCTGGTTG
+
CH?2B@;:<G6?3H2@=96C:D%%7C>"+!A-F-&.2-</!)=6&-H-;4%3A?<66=1%&H!7'H2D8A'?@)1@3"1,0E('+7*)/
@r6584
NCTTATACAGGCATTCGGTACAGAGCGTGGCGTTAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGCCAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTG
+
'=D':8@*:#%>59F$GD@B%<!3B7?6H.*&F17(/976B(0&E!19!>;>*B/0E78)#@$#/A6)FE67F8,0,*#A#",E;FE:DG5,:89<?2B"%6G2#!@1%.461>+09,H.*5B4
@r6585
AAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATTGATATTT
+
.'D&*><9<6*9D;HG=.F1?<8&1#8G/4.4>(=1/C?14>EC!3!59)D/47$7AE53+G,,A-9G3B06D#/?";F36;-1'@F?6*HH7+26E@3$?&:")'8%9G+2B"B!9:%(4>D1$:=(C,,3!=%4(*=&10H;%%7;:
@r6586
NTNNNTNGNGNCTTNATCTCCTTCGTGGATGCCGTTGACGCACTCNCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGT
+
'$!"'&%$"'#''$*#$(!&&'%+)%&#'&#)%&+%'"!*!+##"$$!+*$!&#!%"+)%)$'&+'&)#%!+*$#'&(%#((*%#''()#%'!++*!#**'*%!%+#+!*"($'*&"'+*+*!*%(%#"&+#$!"&*")!#)$&)#!%($#*'&"*($)"")%(#)#%"*!"&))+"'")'+*)*'#&!*$"++)!&&)"*+
@r6587
GAATTAAGTCGCACACCCACAGTGCCNGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCG
+
1H5$070H4*&F7(B6E7#,,F06?%H,&;0!;7$B))>AA#$H:26%?E@C4A=*!.",4.<,"0F?
@r6588
TTTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTAT
+
F'.$7)9H,4,8F*@H?9C9G-.21BC8F".5!01%;9"+)-
@r6589
TGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGG
+
8/,F8GFB2@HA((7F?89FF!!+.:0H71-!,"@;?1@'.739)+9;H>0,(8E,&1+EG'07&=+8D<&+>7
@r6590
TACGAACATTAAGCGACTTACTCGATGNACGCAATGGTGTAGCAACAATTGCAACTCNTTCCCCAGTAGTACTGCAAGAGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCT
+
77<>G3@24885D">!->8!:#<9"7C1&)-6"C:=,2:B1')'9++.5E.&+=4*1+A,GG+1>645F*B9&#@:8/4&%?6:#,05GE+H?823.*%EF-?7$:'G7-=6>)
@r6591
TTTCATCAGGGCGAGATGCTCAATGCGTTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGC
+
HB533:5104.;H,;)"1!;*E(/0'2E@0FDB!4G<21"==B<?-*9#!B:3=/.-1"@*-0D$AHF+A8&#"E>9(1:E;GBGC/*$7@/7D/2%:?4>4.#A*-AB2:<H!9'25/*&3.!$;990,H*>(BB/C9F)&3A:19
@r6592
GGTGTCATTGAACAAGTCCCATGTCGGCAAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGC
+
G#F&=1%=?A),1<+=A'4%)$*0%<<#AD1-05D8$-F@$)+%F8B-%4H5H3/;-<+-GG+9BFE9G%$CA3E1*2(=6!G+:.74@(B>>=BE809H$!-'59,&;930;$
@r6593
GCCAGCNCCTCGGTGGTGAAANGGCAGAGCACCACGCTGACCGTGGCCTTCCAG
+
!@D<*,#A1=/E*=.E>8$;762F,9/A1C77"3BB?1=2&.*00<,&C/.-22
@r6594
AGTTTGTCCGTGTCCTCCATGCTGAGGCCAATANCCGCGACATTATGTTTGCCGTCTATGGTCTGCTCAATTTTG
+
6(>/$$&4%;9.---0*)A1<=5!9>A98BHB:;.819:B35D%)B!7?FE*F&=+.+)$<;(>/22!/#(=$65
@r6595
TGGGGAATCTTTACCGGCTGATGCNCGGCTATGCCACCGGCGGTTNTGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCA
+
&8)1(,;%(H98B!BB/#E6=#74-(1E>>=9H7+&'<&#6,'"D=2-1H2!=&E:2533(>(0B7;.'3!:D:5<C30%9HAE7#%-.0DH8:%>0982C!F$#;
@r6596
ATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGTTCTGATA
+
E,;9=9!?0BA32-7=9D0HB':=G*A6+"B:)C7&F+=!<7&F8+03<<'0CE:%&=?4E841D2+3>&>(
@r6597
CTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCTCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTNCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCC
+
G.7D/4.:>/=)&?'5='5!F29/>+3C,GA335F.A21%F?H54@0C"B&7#9(;/C?+1%',23,,-(,9&5C9E7-A2;*,30$?0A&CA!@+/D0.HFBF;A=.7E+*955AGB";6)9&0*!/-!:<*>#:87(A1)'+63:59?7%-!(+!9;":15?'4-8+6G6'4%F&5)3A!=*-/$4,D*E7(G%C=9,.=.4915&",<%!!1!68G61G(9.8"/+'G+G5/9:')/&ADE<%E0!&HE*A$#(E5/B<)//EE6!#(G%0>?&?D))D'627C
@r6598
NATAAACTCCTTGCAATGTATGTCGTTNCAGCTAAACGATATCAGCAATGTTTATGTAAAGAAACAGTAAGATAATACTCAACCCGATGTTTGAGTACGGTCATCA
+
#49%>%.H<$68##;1D%0=92GH=A2/*5?9?3HC@/H;<H&?8D&?@5=56:(5,<8!?6@%4#*=0,!/B:0-468)1)&@%/;-A!/$&!*)BE08C)7E<E
@r6599
NTTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTT
+
%?9*:<&#G*GG+129"4@8E$A'#=-%F&D3%5DB=&6E!7
@r6600
CNTNTNGAAGAGGATCAGAAATGGGAANAAGGCGANGTCATGAGCGCCGGGATTTACCCCCTAACCTTTAT
+
)"*"@G06G;13@3#()?2C!)$/"EH$#E/2(3$"D0:88?G**AA&C,C$G,@C682*8;A/B2!2&%9
@r6601
TAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCANAGCAGCAACGGGCNAAACGCAGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGACTGACCGGCAGGCAGAACGGGAAGCCACG
+
(AD6:.579;@6!><)G/=GA""(+!=!/B)@H(7&6$/!#+3C?:>)H:+5$*,*3,-5BH>((/-5'/1-#5=C.&%<'/*&-5&*:,B:'3'*=#A(5%@(.39-08*B)!"-@*-><5*1/'F74)+5H6#3(B609C%-(EH$.@$D=C%4>9EE-A6<5598D%+75A<:/?+0"5&"7.C*
@r6602
AGCTGTCTTGGTTTGCCCAAAGCGCATNGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTAAAA
+
@-9'<*?*#E>B"4:3DAF1<#A+"495B0?:.9+&$4.)C:A"0@%*HFA5-:-0GF<*'++B'F71,=+8.0(01*,,'?,$BG9*/B2)-9&G30."#ECGD;
@r6603
TGAGCAGCAGACTCAACAGGACAAAAATACGCAGCAGCAGAGCGATACCGAAGCGTCANGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACANCACGCTGANGGTGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGGAAGACAGTGCTCATGCTGCCCTG
+
;7HH+'=).9'D%DF4/GC?-!;!;0%4!;3?$G,8A=.0C2;)+>'86)F:!A:"20=E6.9H&&50H'+?F?B&!G>?,--%6H""58+#,C/C8H91%D@!H14>.21)-3H!DE7%3/#!7%,=)3F>5=5'$B8'"G<98*+<;?708/HGF8"%GB6C5@&+>)G5)23?G4"7+!"B3)@+/*&6070?>?6CE@$!>.<3'&5&=!)D!D#@72=3%%A<#(&0>7<C$4B&,FB;2954)2,/F!8:?C0G?G35H'D+!**=>'&(:9'E,7/864,@;/-/;1%%+'E(8!0-
@r6604
CGAAAGANAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCGGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAAC
+
$2(&>"$;6A;7504:728/G,-04B2.6D8569?8B0@419<E'A@F"F,:+-DF-*2H8'F"DG--3+DD+!2/<GF-)8<4G%(;-9,&"F@4'AFA?<--(=H$A*7+;!;
@r6605
NCCNAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCC
+
!$&+')+!))*((+')*('(!#!()'"+#'*"%)%*$%%%$"!)%*+'&!'%&&"'*%#%+''''!"%)!"&!"!"!%)*%%)#"+&$*"*##%(#&#)'(++**&&!!$!+*)$)+($%%#$++%)'*$*&$#"&$()!"""$*"&+"($
@r6606
CTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCTGATTGACCGGCA
+
HF(4>!;(,5<2&6@02.(=%1"75"H3@E++"!/107"B?!5;E%C4,7D9,,F8&HH5
@r6607
NATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTACCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACA
+
$DH9E+#8<1G<(A>3%0@F09<>,:6&"F&'D?A3CB?,1$:C<5$,(G4B;:5CG0B7&?-(/CH&?F4-C?:10HH%6*G.#*"#%*5H*((747<4''3@?D)0$HE06B@E$8H4D
@r6608
TATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAANACNATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGT
+
<.!D24FE'%0,)/#3A.":B@9!:;(%5D>$B';&%13B=+$@-8,%-9%8831+A.+&A!6@73H0(<$E(!-%%#G(+%1@*CHA"34)'3(1G'56(BE;/+<&.6=59$&#E>)$!46>;3
@r6609
CTCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGGAG
+
84E-9>?,1#3-2E'>C0=DD%E#9H?81G&1FEBE2&>D83/3!4382*A.HH12H&6
@r6610
TAANNNTNNNGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGANGGGTAAAG
+
!&$!"$&#*##&#*+&&(!'$!(&$%(%"+%!+!%$%(&&")%!#"$!'("&$#
@r6611
ACCAGACCAGCGAGTCACTCAGCGCACTGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCNTCAGCCA
+
122+2H>A$;G&AA<B&E5(;D&,5*),#!=#D2<*28:9C;@?5F.B1)8A9E)F2G*<G@.$B/A34,A3B@*&
@r6612
ATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCTCTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTG
+
/C8%+=$A(7C:!!$46,+(@4FG2D#1H"B)7=5&<.'0BGG3D!A1*@4!%$@8$<679.)2>!72'40GC)A&:(+3+?(7<<E=,4,@/A82.542!$9H+B<;27F.9*=,.!8:=@00='31+&8-4AH3#92.#<E/27'%=?,>.$EBG8(,.$57/AD0=132(&B(G"=E@$B+81E;7*G%5&:2D3A"447,<"7-?.<C!>2$!=%#'%3E3'20#82("&AC>+9#%GB&&:5?G6'0.>?>=H0((A<+'8$@HC%'9@37.D7=+:5*C-#"()A$</G90/=H1%>?+->7&;4=5G$-@A/2/=3B/G-/(FFD1=#-
@r6613
AATTCAGACACAGANGCGTGATGGTGGCCTGTTCTCCGGNGGTGGACGATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCT
+
#+&$$%'%+%+)&#'$%($%!#)"!%"+""*'*#'")"*&'&(&#()'##+"#+($%!*'%*%$#)!"$'$+(!&&%$(%&!'#'$(%&+)#%%###*'!#%$&$+")("#!%"+)"
@r6614
GAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGANCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTTTCTACTGC
+
2%GE3"C?A5,0D04(4$>!#)$>.=D6"'>>1GB#39%@<E=B,0C)!46"D=(F5E-D,=;8?7'C3*.,0F*EG&G,7:$7:2E'/-#**9572#@HE&4>+G2?A<D&0*),%&#A2+7"&'E!>$'46'GE)=E%,E!.3-+D8;12;,(H'H1E<C*CD?/7%9=<8G',2+"0E-C
@r6615
TATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTAT
+
%C90>F#H,5+#3.AF)<?&=:9G)5(H<C5:?+21F.)+%
@r6616
TGAGAAGGAAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATT
+
C321((EA=AF:635#@E7G$39%"1:?$H%.(7!F:"9)9+-"1*F
@r6617
GCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTCTGTACCGCCGGAGCCACCCTTNCAGCATGGGGGNCAGNCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGTGTGGCGCAGATTCTGNCACCGTAAGCCAGAACTCCCCGTATACAGACNACGGATAACGGTAAGCAGAACACCT
+
DD.?3%%.:.87.?9G(,7<0>A8-09F(C,2G/>-58)$C1#D43!G7)2B=?F)+=.)0?1#/#?"=,A/.(&A;H+3.F;5/G;$;D07BD07)+<:#/3G:3/=>(G35?.C";,E2).:=('E'%#)3%*=9!B9F+C6'>().6)-?&'(9#(+H+6%C709#E721;HG,(1A.D:'H:3>;F12,:(12D!"9%>->B*<H>G1G!7<@$;58.
@r6618
GATACTCATTTATAAACTCCTTGCAATGTATGTCGTTTCAG
+
@C)*1&+E0-92'?)+274%('7/!1!GA20!G)G;=2:>;
@r6619
TTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACA
+
68>'@C(>9-*4GC)<F05=<,2;""1$D9C*'6!5D2<""(A>F!E#@<CD@
@r6620
ATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAA
+
+9,>"0>A$*+%;"!(/@&'B/A-&6@/)C4D7F*/;@GC*G$7G*E"1;;60!/'$F$?3*?@:FFF37":C8?H+3)
@r6621
GTACTGTTGCCACCCGTTTACCTGTCATNAGGTCATGCAGTGCCGCACGGG
+
-:C?A;CCEA3*#/!1<=H"+29#<5FB'D'%B'9H9)6C"%@*GF1B.?;
@r6622
GCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTNGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTNATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGT
+
&EF/,'B@-H%@?:)F,A/BG+98:F+H"-&?;=9$-)/3924F$4"53F#4:/--C8D2.*A#:D6<>57=&B"((#/C=E$B7;;+#6:'93,A'+2AH'/336+26D<2-303!@@H?$20/!D91E6720","4=!:H.68:84:+6<-B"D.,G2?-$464/1?H1)<H!15.?4&?(.8:%3<:">9-7CA:!)6D>#@'0>G)G!HE=BD$<G43<>='/-A@8'"5+B:A>7#:5?.'@<;("457/(!2
@r6623
ATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGNTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAANGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGT
+
3%<6-CGA*&5D?CF;0'8H<5DB9%%5&-+:-50@C6C.D/>FH.BA$)$;=(HD5!1,E5C67?7*1"'E5+=3G'+63#&60H5!%DE5%8H31-1%!B&C?7+%@8(A1(G/=H3@;*GH>1*A:H)A$E?"0(6E=)!HF;>9(&$<-"78#C%"&4C@A--?@A&=4A.(;&'?1&=90+:FA:98E5)G-4,$78/0C0H%:*""*'9<;-((;*2,7F8"B93''67!=*@*(8424!D=)"+>:.B@$9#5)69#4"=8-=0/13F7(&/%-6A)E+$(1!!0;HHBD.B"*5D=*@<8(E<6$5123CC=!A.1G.=AF<D
@r6624
AGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTT
+
:,:=D0G<,?%E3?3*#19?$*/@5@6FH"F;,4@-(3%!<&B3(&-64:F'>'
@r6625
TCTGCTGGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTC
+
-*9;%1F7D'1B>9=6*.BH-GCH'-21;'&/AE%=:D!)'.17BG0)8B
@r6626
ATNCNNCCCGACCATTTCCATCATTCAAGTCGANCTCACACACAACACCATTTGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATGTTGCGCCAGCATGATTAATACAGCATTTAATACAGAGCCGTGTTTA
+
()$($!('((+$$#)*%+%)!!"#+($$&#(**'#*'("%($*$*$"!()#"!'#)%*'#$!'+!(*&")+$*!&++%+$*#(%"$(%+#&))#!!&%(*%+(!!$%%!(&))%$&*(+%%'!(*&+)+&#&%$'%#*!
@r6627
AATCGATGCAATGGATGCAAGCTGCAATCGGAATGCATAGTTNAGCCTGAAGAAATGTTTCCTGTAATGGAAGATGGGAAATATGTCGATAAATGGGCAATACGAACGCCGGCAATGATTGCCAGAGAACTTGGTAAACAGAACAA
+
'$%(#++&"!'"!%'"*)*"'%%'+(#+#$&**(#+)+&%+)"*#&!%!')+"#'%&+#*#(#)#*"*'#!)&"!"!)&()&#'!&(+''**"#"%)*+)""'('%'%#)(**!!!#++(#*"&%'+(**)*!#')(!'(#($)(#
@r6628
GTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTANCGTCAGCC
+
4'E0/9/!-#32+9-B<;.9'?&:&!:/3<50%:H$C"B>.D?33H0F7-(/00=7/<C5!*2
@r6629
GNNACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGNGAAAG
+
#!))+("%)**"""'*%%&'$'!)'+%$$*+#'&*'*#*")"+'&*$!!''($("#$"#)!&%"&''+%%&+$)(
@r6630
CAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACACNGNAATGGCATAT
+
3(,%#.0:?+(%/8&<%4&%+,!F=>!-@,G@;@#4!<C(*-966/,,1<5@9
@r6631
CNACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGA
+
'.D<.=)'#)HB#C5CH@>6><++!>2&43/#%'/G<1-F%2
@r6632
CNNTTCTNCGCCGACGCNGAAATCCACGGNCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTNTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCANTGGCCTGCGTATCATCAACAAGCTNTGTCGCCGTCTNCCAGCCGTTGTTCGAGGGTC
+
$"+'"$'$"(#)%&*#!#+&##$'*(*)!#*!!!*!%+'&#)%!)$"%*&+&$##+('!*+($)#(%*"*#""*"&'+#(&)!"*'*&%')'#&$*+*!"$$'%!&+&#()#*#&)'!%%"%((&*+"!)#&#(#(%!$)$##%*#))&!%%(%'&'%"%#!"('$!%%(%)!*("&$"'#"*$!++!*'''"#&*%*$%
@r6633
TNNNACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAANGAG
+
$$'$"+!!'$&'#%%!*#'#)%&&&+&%&')$"+($+!'!!&$'))!
@r6634
ANCGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAGACCTGGGCAGACAGGACTGCGCGGGCATTCAAATCCATGTGGGATGCCGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGATGCTGATTAA
+
*$%("+(&)')(#&(%))#"*%#"(+&$+$&$#*(&&+"$"**#*%"*"%')+#"*(""%"%&"&&&$*%)!+!**#)&)"###)+#+!#'&'++#$!')+"$"+!("$(&&#+!*$+&&*'$$(+%"!%'*)!")')%*'$#$%"#$$#+(#$$(+'#)!')%
@r6635
GTTGCCGCCAATCGTATCGCTTTTATTGACCCGGCAAACGGGAATGAAACGCCGATGTTTGTGGCGCAGG
+
4-(9-H?',D>A=/9)<A"%EG">''3%-6>*.(1F8(:"C)"BF(C..=&,+/H4+G3$'&F.#+;A16
@r6636
AGTAGTTTATCCGATTTCTCGCTGTAGGGGTNCACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCTCTATTTAAGCTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAANCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGG
+
*(8E?5GH@#!$AA518+6@CH)G<2-H7*%D4+A5H8359'4,!/%2E;"60=DA*B8C3?:/:.?8&,7@G."D:51H&0@-?43%.C@,;<!6%/D$583"H&5'H>89%=963")/4+-)59*?=0/C/=;H?GA1+.()-*$)'!5/G:$*1/&GE>=BH28&%8)$;5'3FCH154(08&3F$8</F+;%)&GF)!=*>()$5)1&F/79'.95.DGEDA$=?01=.4A3!E",$2EG*7)8B@6(3.%246''#(F:/?2"B#A#)%7F).9?H@-'#F&.E9:@
@r6637
AGGTTCCAAAATCCTGCATGTGGAAAGTCCTACGCTCAAG
+
'9EF9")4&G#7>.>C<%9'>GH=9.B*#'35=B*#D3CC
@r6638
NCNTNATTANGNNAGTTGTACGGACACGAACTCATCAGGG
+
%%$)$'($&%&%$)+%+$#'##!$"'+##$!%)"#'$($*
@r6639
CGCCGACGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAG
+
.;.+%7!*@9B%03&4(#2C/$4@?.:0<<193E'%G=*8#%>=)/&DCBH4.DFB(9-9)C8A?7@&EDC0!H0>
@r6640
ACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATC
+
,"?3*$=<:5.?5.35(63>F3>*(7-C5=<!125*F#,D3::!;1$@%<=7-
@r6641
TTTCCANCTAAAAATTAGTAGTANTGAACTTAACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTT
+
G.+8E-@/<%F$6-@0@)-,#1A?/'"F9@?&?00;!&.7A<<909%EE%"9AB<.88!2!5BC$C7=;0*)4"B7118@=
@r6642
CGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATNGGCATGGTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCNAAATCATCAGGGAGCTA
+
7?,7,FF4*)4)E3!=8>"HD>6?$D03/D(*:>E6-'838*#>4%5C.8986B-4!6"-A&?);5C3G<5&4/=8#4#C%#;*2*0H*#135%D<D!2$,38!"7$CE8@."5
@r6643
ACGCCGCGACCAGGAGAACGAGGATATTGCGCTAACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGCGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACC
+
B82;04;@4/,G937GF&88-6(!;EH7;9?&(@6<<A/!F6:)F/-4?DC?7&+-B94:+!F';F7D#*1$-D*4+=!3:D"B7C39=>F((9;?@.7&<.6%(CE"*+<)="=F$1H'A%23$=DC9&FF,:'*>B/B,+:.0+82+7E&B.4"&8.)$%.4)<0EA8HHE!?%
@r6644
CNGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGNCGCCGGATCGCCCTGCTGCCCNCACGCATTTACCGCCCGGACT
+
&&?65)E9)!@9?+'78,,"=H2<!E'G304E6$<'0-B'-'$'B&%B>0:!#0'10.+<"5A/)C(06BD%$E&*=1?.*28HE8C8<>3?F"5AE61F'
@r6645
GTGAGGAAAATTTCTGGGTAGATCGGGTTTAGCCGGATGATGGCGGAAGTTGTCATCTCTGGCTTGGACGGGGCGTACCGCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGG
+
;1E<3/?G'/%;@#2$;7+D=H):7-(!G1F6,GD<7@D4-E1#>E7';4AA9F3-;:C#9DA6AA2>5'#?*'E*-=A29.40G'=2ED6'--<>>8A2G7GE-043$.A+#&&%"7".58'%5(G(H
@r6646
NACTNNNTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGA
+
'$"$(*%+'''(%**)+'!("""")+&!"&(+$+*++'+&+!*%$%"$#'$%&)'%)!*+!(#+%!*(("+""!!!"&'
@r6647
ANTGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGA
+
*"&+%&$**(*$('++&)$+(&*""#$'!$+'*!)'$+&+'$''"#"#!"#"'*&"$)+")+%$&%(!'
@r6648
CTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACNCTTCCTG
+
+&)'"$+#*%%++#*$**$%'""+*'''+#(&*+*+$+%)*'$$&&'&)
@r6649
ACTAGGAATCAACTNCTTAGATCGTATTAGTGACCTGTAACAGAGCATTAGCCCTAGGTGATTTTTGTCTTC
+
*()($)$)($#*))!+*!*!**)!'%(*"(%'(*'*%)**+&)%+++(+(#)!%+#$""%%+!#"*$$'##+
@r6650
TGCCCGGCTCTGTACAGGACCAGCATACGATCTGCCGTCAGTCCCGCCTGATTGCCGGAAAGNACCAGCGTTTTGTTGAAATCGGACAGGCTTGAGTTGCCCTGATACCA
+
%":1HC57)991@HE0+?..E!#D4?$E-%*..=!5GA%*(9#&.;%$!;5#7+=H+=1B:5.5$C/A",8<@ACF.51/:+1!8*'3D%"<(&7!0D)+%=+.C4)'4+
@r6651
TATACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGG
+
)!6,83D-(3+!?6&<*($.65H<B$3@:FE%9GA/*!C3(!3#6C:3B
@r6652
TCACTTAGAAGTGAGTATGAGTACCCTGTTTTTTCTCATGTTCAGGCAGGGA
+
F9%E&@*46G6=.-/0:<F3&*#+?$8DD50=,+&/:=).=!$*HC;D!6*A
@r6653
CAAGTGTTTCCTTCATTGATATTCCGAGAGCATCAATNTGCAATGCTGTTGGGATGGCACTTTTTACGCCTGTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCATCAATCACCAAC
+
D.7:';+"=0*4>,B9%.GG9!B%)DH++5B$:.4*A8>$$>;@BHC2B%>,*2".+'%&6EEH("B)B</$2/AF?9',4,1=70>9'2-&+'A/"<*3?C?*4?&A8'G)A<*7A*(*)'$3:&04(6':8!
@r6654
GATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAANGGCGGCGAGCGCGGCTTTTCCGCGCCAGCGTG
+
-0'1&H2,1/5,DF%3GG!/&=5+=&=+7H(1B<')'8#F!>.#)?G'/=<$3+19,.GB?E-0>70',.&?2?82F
@r6655
NCNGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGANTTGAATCCTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCNNCCGCACCATTACGTCTGCAAACATCGANCGTCTGNGCTTTACCTT
+
!&'+!!#&'("##%+$&$*)#&(+*""(($!+%*##&"'#(&)!#%*'%&+()$$#)*'))*)+*"("+%!*&%#"&!#)&%(!(""+*&$&)%#')'*)$%('**&*!!+"'$$+#'+)##(%'*+)$)%#%(++)&!*$$%+"
@r6656
TCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGNCAGGAAGCAGTAGACGANATCGAATCNAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGNCGGAGTACCAACAGAAAGTCA
+
1,5&?:#.*6F***6D2102'./,0"$52(&E"<):.+E&&8F,A3A0C->&*@+F+G@!$A#)019G5;((B%@7,:,F@E/C:++?*H2*4)"24,$F#:49.F5?D(1*@..A>?=!/3FB><?>.'(<)-A.4>.G!)?F7B;C@H<E@81+*/!GB4<-81@34HB'0=@34(1A4F6!1;0D!)B/C,A,/FA20((90@
@r6657
TAATCGNCACNGGNGNANTNNNGNNANGCAATNTTAAATACGANNG
+
$'!&(#%&**$**''!&)#!'"$#!'"'*'*%)("$*#(#$**"#(
@r6658
ACGTGGATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGNTATCTTNCTGAACTGTCAGACTTTGAGA
+
:)&/5;%*+><G9C='C69$7#!8C#>::'@D+'!"'.D+,*<)H:H=#>/B>5:F%F4:47>0.2%D-E5<A(9@0-!!DFFH574)
@r6659
TATGAGTACCCTGGTTTTTCTCATGTTCAGGCAGGGATGTTCTCACCTGA
+
'A5F<3$=6A<12@72&2H-<''9G85(&'*;')7,$%7,F+8G067-",
@r6660
CAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCNCGAACCCATCGACGAACTGTTTCAAGGCTTCTTGGACGTCGCTGGCGTGCGTTCCAC
+
,!D''BD+BC/=-0,6E7<=<H)D>66+:/="0A)#;0D.!1*@1/',,4;10+&8G/B:+B@?/#?#E.1G>!=&9,33BC+5A!E$<',A'-@8%.4.*#?=':4!6,<20(02E*84FB>'"@:9;%9
@r6661
NAANCCCACAGGTGAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGG
+
&%%!&+$+'("")""#"+&(+*$#""+&(%*#%&)*+)%%')*!)##)+&%&"%**&$#!"$'#+*$*&"!('!#!$*')+#$!$*'!(#&'!"&#&&+$'*%#"#")$&$**''#+%&(!
@r6662
NCTGAATACAGCGTATGGGAGCTGAAGCTGCCTANGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACG
+
!7!E"@>#F8)/9812H.=!34BC1).B36H=6$1?!EE.:0EA;H$<&G0"F.,;:9HE52H&A)F>A4,#5:BE>,(44*
@r6663
CTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGC
+
+@7,==>94C8B8)::7$5*2#5B?799+&A3=#5F0#87
@r6664
ACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGNAATGGCGAT
+
D)<@1;7"D:5!A10/#C*79;B0%<73A?(-/0:HBC8(@-)42-&2
@r6665
NCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCNGCA
+
!20/H!H<C-6-0>*#$,?&#.>8E3>A3,=1+<A1C+3.#':H!HA/@/59;/D!H&94;F46=/)+G5E?:7B?6?)%>.6
@r6666
ATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGA
+
(C3*:<#C(A"*#9;>!!5)*,#D@B26-(58C7;?E-1;
@r6667
TTTTGTTCAACACACCAAGCTCAATCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTANGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTNTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACCCAGATANCGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCGTTTCTATACTCATCAAACT
+
,.4*)-6G5<.!HHF?D+B$7,0"D04(?)'=&2;9!>D.#B>HE9E'++D$2G%)1B4$.&%D+;F3G?CE*7<!CB&=H/<5H">35#2F7*872B$46>D>7<+D,2E4.1CD3<F><A'.G>-;#@2;<5:E71F3)&2(%&?$4G.5C:-2A'9,,%2E0.484&%41D.B62?9&>((+(";:?<GH41=%3$4>3+9&!:397>C=?-.":8<7:478*&=&3".7"F*+$@6-7?DG:+%=4??,-@@=2;#A(9F08!<$=D5!=(!*=$1G6)2E%G*8'D#C37%4?D+9#(BH0@B(GH.=+>-:?#-:6.*+:F))/%/21=-F:3+"A;*1-)3'$/0/B@@/3!4<"E9F,!B@1>C:E?*11?A>;,B;"#;A*-#F:D-37-2/3!.)!?*@//#/;G97D7=.!9G5"B324:?+?<$
@r6668
GTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTT
+
('939@1*3@+=,<&=)8E>,9?H#F*FE%4!:9<=&F(825=333;#+?:.D&H=((>D3F'C0!,7=.9:4E+4(&8-;)C3;"%1.;'22/E39CF:*G:4=0..*8C2.4$C"9-&3706:.?3*'#%>&?;B$"HG.B-;&=4D<G+F3>D?)(!46:D"$=+59(;>%$7/<:-(1/=%6'7,$7!&-.,@%G@HE*F&EH.5H&2>6B0>';173
@r6669
ANATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCANCCACCGTTACGTTGTATCTGAACCAGCAGGCGGNCTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACANCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGNCGTAATNGTGCGGGTGATCGGCGTGTCATATTTCAC
+
,412>7=A2&>)EC!H:0:B45951"1CH4=H'D<?>'61A+)9/(6@#40G)86+GH)):E:3'449AFFE->);AE!4*+B.>3E$6$3A?+2?/@18,"C':B>502&8#E-*2G#=F5GA=H)6E..+FEAG%7+0=@B&0!'>4B:.H,/*@3*GB:B9@9<1?B1B30(661/C!8082"%=)?E&%&5%D-,7*H"2>$"3D4!?
@r6670
CTCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAAT
+
"%C=8&')>4)G,D.(F77@2+1-*G;1"G.74!;9,1C<&HG*95,H);$7,;F:1F8?2FC<D2"<-G;D;4)0'<*)"B*!<%4.
@r6671
CGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATCTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAA
+
$=?%$7!H3H"6E2*.C,3H87:?-@>B!()=/D<636@G(C3!&H@,C;#*#%2A!F"?:8G;.2)(?9;5(,:#61A>8!E@*7+#E5-AFC'99&8$;:/-#4::?$=.>';.&/#<@/+E2C3B$>E;#AG@5=@7<5#.;$E/;*HG#>"!H(<F.9%;CA.3#*1-C"22#!5@
@r6672
NTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGC
+
"@.?8"@*?1#+7E<HGE'8DFD:3E--$%FAG7)/7&$$C35>!@<-7'+&%4/%7D57G:2@/F>#7%H55=+.-40!"-9HFG0F.8G!,DB8.6><(4'!5(#8.;&&C&83<EE04,#:D+-);@?HH)/2=G>CB*'/6"1D%F*<>(FG)!75A5:>/2+.%?$B.65CG68D*$45E82@HA>!*"
@r6673
ACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCTGNGTA
+
%7F593@D"<-:%=1"A2)H@5*#/=<D%GFEC(>E0(=FA75F?A852)#<C=9>.A7,,6/2*&:*G;-H1&-(<E&%?:9$1!"4H9/8B++>-,8#
@r6674
CCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGNTGACGCAGGCATTATGCTCGCAGAGAT
+
"6:<>05$$H77,->7-?'?+(6:FA&)!0E4D=5?&&.0,&9',.%0@#?4%/56H&5$3<6;*)8;F!2B=,@(DB
@r6675
NAAGCAGTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGG
+
!0.G#*?'7H('?7,/.-?'6%&5>'$F&262,5((66$!@:!;,3603(08D24+2);:48)&0-&&F4-0377@2#8?$=EB35H5-%1$?C-4%#=G0EA")/'&!1-9@3*;+?")419='*>/!C113-@11)H>C9D586/5:8*@(B&+!:6-'>1H,!H/::%G-.:*$===?&??33;@%2;
@r6676
ATGGCGTCATCACGGTAATGATTAACAGCCNATGACAGGCAGACGNTGATGCAGA
+
0D73E>0=-*2(80)"-G@252!B!#;9>(307(8CE%A.1$G1E$!%'"";B7>
@r6677
NGTCTGNNCAGANCCNGCCNNNCTNTNNTNNNNNAGTNGNNNNNGNNANCNTNNNCNGNGATGCCNNNNANNNTNTTGANGCNTATCNGTGNNCNNTNGNTNAGNGTNNCGTCNGANNGNCNGGTNNNNCNGNGACNAGNAAGCNNGNCNANNCNGNCCNCGACGNNNCTGANNNTCCNNTGGACTNCNNNCTNNAAGNCANCTCNGNCATGANNAACAGCNNGNNCNNTCCNANANNCNNNNATCNNNNCANCTCCTNCNNAGTNTNNNANNA
+
"""$"$$!$""$###"#$#!"!##$!$!$"#!!"#"!!$$#!""$"##"$!#"!!##""$"##!$!!"$$$!!""$#$"!"!!!##!"##$"!"#"#"##$"$!!$"!"$!$#!#""#"!"#$###!$!$"#"$"!!#$!"#!#!!#$#$$""""""$##!#$#"!#$$"#$!"##$#"#"!$"$$!###$!$#!"!"!$"#$!!$$!!#"!$!!$!$$!#!$#$""!$$$!"$$$"#$!"#!"$"!!"!#"!!"#$$"##!#$$!$"#$#"!$
@r6678
TCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTA
+
A?7?<D6'3-8F:9')G&3C#@/C#C&F#"<4<E.%?/C?#83;5;GH
@r6679
GCGTTCCGCACGNGATACATGGTAAGTCGCGGTGTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTT
+
51>-4:&0C.F+#!<>(><-&43F'&00;>4=1#HF1*:?+$:+)./:0*))"0.C>>&*&1;F*:D-7/B5$0E-
@r6680
CCNGCTNTGTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAAC
+
)#*%''$(&#)+$*'+("$)#+('###"*!!"*#$(+&*!#)"'!(+"&$'+(%'')#')*(
@r6681
CNGATGGCCNNCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCGACGGCGGT
+
'%"''*%*&&$&+*(+#**#$'$!)(((!*')(!+'))!*"$())$")#++(!&*!#*!*&("%%&&'+)('#+('*+&")))*&*()#)*#'*#%++
@r6682
AGNGGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATNGC
+
('$"$%+$*!%!%"((""(!#$*$%'!%##))(+!()'%!"(&#
@r6683
ACGGGTCCTTTCCGGTGATCNGACAGGTTACCCTTCCAGTTGTTTTTGC
+
(,?=;=-2$3A%*2/34$2#)"C0C"H+2+$2!67?)F=&=8DF&3A-D
@r6684
GGGAAAATTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGG
+
$8%4A#B<:!/9H5>G'$-"**0:.3EF::%&'==2A'/"!'-4.*0+>25(E5"HC7'3F7:%3G
@r6685
GTAGCTACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGGCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGC
+
+6A139'(49!62?.>@-:>>3E-8D@A5,+*!2$"*-77=C<=A81:E!2!+?5>C3-6-2E78B.(AA.&//4G74-"@=%'-=B/C"<#+,"6'/?C>C"'&@4.();9GC9*D(8)8%?3%)'2.>#;/?7!,>,E=@&G0&?<3#2<0H//5$6!,,"C/.,/D+.B79D(;)>)@;/D*5G@!)'G:)4#29*5494C-,>4
@r6686
NGANGTCATCCACGGAGTATGCCGACTGGCANCGCTTTTACAGTACCCATTATTTNCATGATGTTCTGCTGGATATGCACTTTTCCGGGCTGACGTACAC
+
!;2))>#,4'-.);$.A+HF5>44E*."B$F5FEA@@<2><95H>5;2"-=G2;A7//(;@'->;.?G2.A1'*F'+H'A$/@;#G">+02'=;<5&$H1
@r6687
ATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTC
+
3!?6"7;C#8A,/3H$%7'A@@C'@.=*F55(B#$/9G(A*%/$%3DB8&5/D1+&146="0$$@BC++*B#&*6;0@.'F/),926,0:'$+63):C#G.%/FHD!7%:)7%)/(GCH+F
@r6688
CATCGGGAATAACACCATGAAAAAAATGCTACTCGCTACNGCGCTGGCCCTGCTTATTACAGG
+
6@/"=<GF*+%.4?BEF!A?!+9E)2%DD'#,0..3%,;72,5B,,0%&-)?;DH"7=1(":D
@r6689
NCGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCNTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCT
+
",E?*;==B63B'?D/H;'+;%!.)CD@,!=?F7F6GH6,4:+EB$E=#6AC?D4F2D(%4(A-B.C2'C15":>D0;4A"/5-2%=HB,!120$"C84'03+D*<#>82"'</A</%)47<-%3"#(=(2)CCG@G+EEG'H0<6E4+0%E9>.<C2#8&%+<>:5(A(1):)91E5$<G53!C)F29CF-$=3,D%8$D!@GH>1'+"E53#*DB!81+,,/+AF(04#H56F3F/8:,.7!1B4&0@7H1>(=&)+)-;H#,*7)D'#@2&:.BE,#,F%=36?34<+@+)2,D&&E*/72-8-$*E=H6!:8"%C-.6@),?!22:
@r6690
CATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGC
+
+%*%&#$&(&&&))$*&$"#((+'&*!+%"&(!%%*'(&%"!$+)))#)%++)#!'&%$!&*()+(")$%#(!)(+)%'!*#&!!+
@r6691
NCACTACNGGCTGGTTANCAACCTGTATNAGAACATGCGG
+
&2!E46:&:;8+0'&1".#+=E*D$:;5CF/4#@*8F22*
@r6692
CNNANGANCNCTGTTNCNGGNGANNTNNNCCGCTGNNANNGTNTTGAGCCTTNNTCCNNANANAAANNNGNNGCGCNNNATGGCNGNNNNGNANAANNCNNCTNGGNNNCTCNTGNCGANNAGNNGNTTNATATGANGTTN
+
"#!$$"$##"#"#"#$#"$##"$"""!$$$!$!$$!#"$$$!$"$#"#!!#!!$#"#$!"##"$#"!!##$#"#"""$$$"$#!##!"#!##!!!$!"$"!"""#$!##$"!#$!#"#!#$"#$!$!##!$$$!#!!$!#$
@r6693
GCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGA
+
@>:2>64H2>:;#C11>+@3?,HE9%(;7;B,E#918%'++B<EB-C&2.?
@r6694
TTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTCACGCTTTCGTGGCCGCGGTGGANGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTCTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCT
+
H9F0;.F&B'&0E3(##>>7C*-7&)(&5>B:=G0&+"!#B"4HH)B#5&B=@"47@%$%0')-6<#!FD.3$!15!*',C;=H):/6"$"C6E18&"-B'!E36?>"=7%>H@!7=9=7B-'>"9CE"E=#$?3G7$<4(0E9(=)>(4=/>/6(%$%#/5<4D21?DE4"FA2:#.6.$?<)5/+'85?8?43E45;-B&=</*$7"F0C%D9?%C7G>7$*D96:"7C>$#@@
@r6695
GGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAA
+
'A@.A&0.;,!B(B#@&C"5EC!$&4$&/:*#81>*(+>5=":*D,@+
@r6696
AATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGC
+
,GCH.395922?*C0@D($8?AG/C(=*<?6C8*.5*FH.G?7D
@r6697
CGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGT
+
8=*'72.%/3?31?9;&?@H8;<E04"F/7.>3B=H;;.:<!+/BE:9C@.'/G/%,.4C<;B:H8%8B
@r6698
ATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACT
+
;*39%3=613$+9,BA@7(0*7!0F7HD@3D&)0.>F$%/6'?H,1233E-#'<F7CFB>0=HB,!9;35+E%=-5G/5*:"CAAB:7)&@"#>$=::9"7>#3G6#<$,#H>F/;'11.)!**;5#B?8E<<9<BF2<H"%;D52?DD);HH5/6.*<!&H($;B)#>A?#EA75/?2,HF=4(',%H="(2+D)=E#0!4G5H4)5&%-.B+2"3.B26,?>-<53$;;)<B'$<==7
@r6699
ATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCGGCATCATTTTCCGCAAAATACGGTAATNTATTTTTCGCCGTGGAAAGCCCCGCCAGCGCCGTCAGTGTCGCATTCT
+
;)'E5E87G??"4?.F:15>?2$0,5=:02-7,,H%3,=".H-B*F)9HB)25/7--',0C(9B*AAB!)<+*+D%@+,F%9=D6,7-2;.GC471?,EB#8:5C4=39(66"/;)@<'!"DG8;6!B49)E=*AD=F>6%.EH=#7471
@r6700
GCTGGCTGAATACCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACTGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAA
+
AC(.G/!1&H8=!G$/!)60/'<:9*:%>*>G65AF64/4D-$$"A+:)+F6D@$9")*!15GB?6$E00:>>$CCE+7G>(4+0!;6/330#'F&%")#!,F00C>5465-?!3/!")$$60H117%
@r6701
CGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGGATTGTCGG
+
.;#=!-9F.>#$$$G&=?)5-H21==%(9:A=1DF8#>&?:".@"'F;EG901+*(%@*E41@GD:5C4.0"$H8+/4/,GD
@r6702
AGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGC
+
H9C-%++/*2G>GF;#$'009&$=.$5--?)2F*"9+AE$CA4?7C7!=C14<$A2#=8E0D2FA=C6%5=H94H:A%EA=@/C%9<"(2'.*+()!@6(@A!0)+(16:/(32%/7;$D+&4):*,<@&%8:)'8(E0C#GH($EE>(4%5/;H7&F2!84,CH:%>F24"F4%BC8D;/<#B4#4C%*+=<0)
@r6703
TGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCNTNGCAGCAATATCTGGGC
+
?/4-%@5C=>'D8!.7>:-;99+>/9A:0/?5%7=,$(A0(C:1-BF*C1&)$,H69D0()B80@:DB"
@r6704
GACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGATGACATACAGCGCCCATTTATCCAC
+
*H88;#//80-'HB<<74A6&<7>'9/3H5,&/E@5B>8%@.5>5(GH**"@,'7?DBD!97)%%2$39*297<8=)3D,+=%=1G!FC7F*<9-"!:)0?@0;C>*"7*!1/)+&GFG+"D#*"-?$."&!<4C@FHDF,%-F(@;AC(A6,$=D?!78A27E2624D-HFG(D(89)5;;/9"8B?4B%.A+%'EF&203/0#/@-6
@r6705
GTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTAC
+
/=%G$<B.)-/,A6'"/434#/A->:>>'2C;(89'GFF$!&G6*C(*<7)/G*E.!9=H4&DA:'A,)F<8.9
@r6706
TGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAA
+
E6F/86+?'43E1(0%D&!:+7@?42B+90851@0<3#!(&EB1*&::D<A3B35)GE/'G;'C=+:5=E9.B=55@*!
@r6707
TTTATTTGGTCCAAACATGCCGCCTTGCTACTTGATAATATTCATT
+
9#60.-&?'&#HC";#:.36*%+:B&:B#&"@57#B</$B.8@/HH
@r6708
ATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCT
+
>%0'9$F)(*>4.#?/09%6(C)H6*+F;09F@3:@/5,>"";+A/'G*H6*)&7<H#:3'*
@r6709
TGAGTGAATATATCGAACAGTCAGGTTAACAGGCTGCGGCATTTTGNCCGCGCCGGGCTTCGCTCACTGTTCAGGCCGNAGCCACAGACCGCCGTTGAATGGGCGGATGCTAATTACTATCTCCCGNAA
+
:=86<')/,C(5B214@7A%8""!?GG+:;C.#,CDBE"#,9,4#,7$'<70,F=EE.@:G)E2C>??9?=+"%-725?/!C'-H-:,B1.F&,/:9(<&$&30D@0H=-?.(>7&<;#7%@B,8#D(8
@r6710
CCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCNGGCACTGACCGGAACGCCAACAGCACCAACCGCNCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCT
+
?=.>BG&A9'-:C-3"H,+D-7!H*2-)/AH5E$/31-&5/?;FH41<$B'.-*2GA@D03"49E2,@D8!F;@9.<.;CBB.,*>=-6H5/256;05C@/';G()"@D3+AC!=5$1)='<!%18:&%8=H6E,*/"/"=1;B4!>>7+(</(H/H9%H;*/C8<(CBE42E
@r6711
TTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCGAGCCTGGTTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATGCGTNCAGGCGTCATCGCCGCCCAGCA
+
%4!?A0.68%:(=7-07C@4,9"/7.(5-H>DE:G/E<B&$!G""CC<+#>-)DCEB?5:B(-2!%-=*5F?$@H#5<EA23B?AG28>:#+":B.52,>;'8%<(;;$?C56E7/FDG%($."@9(/F@@'.$G$?2643#DGF"00*.+7/.HH
@r6712
NACACCACGTATCACCNCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAG
+
&3HA5<#5,5D)$/?22BE$+,!7='#.D1/77!A=?(4&,$C3'C80/(H3D%-CH,-;'.:4:D(1G$E<:E+$09!?$;/12$.+"53";F641@@F?'89D6#.$30$=(='",
@r6713
TATCCGGATGCGCAGGATGACGCCGGACAGCACCACAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAA
+
%/H%%&!%2(!18G(91F6*<=68*#?&)C:."6;#$-9A7//+#,?"7>A=8"5))0/6?C7=*1?5G0()DC)$5B79D.'%.(./G:0.F>
@r6714
GCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCT
+
.(H.<'220DE9E/.3C!H-3?<9E*!DE3?A-<ADDHE8F$3(9A#2$:;#27<'38+"=4=(./&:"$F<*;'$C++F?7(696F8?G=0782
@r6715
NAGCCNCAGCGGCTCATGAAAGGCAATGGTGGCAATATGCGGGAGATTACGCAGCTCTNCTGTCACTCTTCTCCNCCTCTGTTGA
+
!$''"+++*#("&)*!)+*(&$)$++'$$*&"''#'!(#)&#%")##)+'*'""$(#&$(&%*('#+&$#)+"#())&(*"("(#
@r6716
NTGCTGTTTCAGATGACCTGGCATTCGTCTNGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGACGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTC
+
'?/(:<4A5'-<HF-,$,?H4>92!8B/)<!+@26?4G*C'?$=A!&-2'G5-!<G2*)##=:09/7A($?';+/.0BB:7+71G,#9F+1:'8A#E:B9)2.9A&DCA'
@r6717
GCGGTTAAGGTGGTAATGGATGAAACGACCAGAAAAGCCCACTGGACAGTCCGGCACTGACCGNAACGCCAACAGCACCAACCGCGCTCAGGGGAACANACAATACCCAGATTGCGAACANCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAGATTTTGCTACCACCATGACTAACGCGCTTGCNGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCT
+
D6##C$E!A#71F#2A0H97&6;?'+93EB.*,777D4)71!5/*>-4D-FH.(C'*>7?F"H-B469=C$E7.#8,#A%G>5*HA:4$5-FC%A"%A7C#5C7/1%);;(>,)H?*-<<2?B/,*-10'/37+$A('#%:#G,+=H7F@@/,:&786A)DC2B++C-=$E=5"C.E#+2)"))#<H=<H%0DC+$D$&&1'E<&.2'E7E$$47.*/%=%%=@2,$%16:=-#E(4-D.6'"D=!607'1?9=H9G4)*5DG1(/-(:G:*::4F49>"'?$.(/9-3->8&?#
@r6718
AAAAAGGCGTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAANGTAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAAAACACCGTTCGCCAGACCTTAC
+
4*1/3D*!)HA@H5*8E(H/;!G7-9@1C22"-&.9$+3-H/F@;5;F2.4197,6G"<-$H;20302@#'9C/D0=F$@H9#%#.1D/3*68B1$"-5H$2;A,F7<=F257&!EEF-;==:+*--1:(-<E3FAD3*&$"%E;EA8=B6:(%.>#4G-):85.,1@H@H.><@%=A;*0/DGF0G%-0$'8'*7
@r6719
CCGCCATTGATGCGAAAAGCCGGGGNCTGACTGACCGGCAGGCAGAACGGGAA
+
B!?A;!3G?'6"0+(@&$'5,38!;#.A9)?0F'F5,@&$$E3)F3.H'""5G
@r6720
CAGCCAGTAGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACAGG
+
+&(%&++'%#))%)''##%"%*$*)("+)&$"+#**%""+%'!+#(#!''*$%!"
@r6721
GGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACA
+
9#F@(<7,8@H#C&@.&E&2G28<+8,*:420D-"-2!?<*/=5G2C$)"%":D%G-GB6((7'1;
@r6722
TTCAGGAGCGCATGGCAGAACACATCCGGTACATGGTTGAAACCATT
+
7%D4B(.8,<&0(HF<"<=64=;,-$#FG$F6+$)-?0E"1797.,2
@r6723
AGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCA
+
32E*3C8**9?1@;*&$5+?G*562*3;<>)0E.C<B7D?5%1/@%H0E6B8;053?%*-,C!*@)';)-+43C5>#$<;<>:/;C&>*<!@*22C:'%B*%"(C*+G4%+<C:&F%B,=G*>.)D!6/5598/78B-BB2*'F3FA&C@51F6E5!%0F4$;$=<4AD)=5?86()4<#H+H0F1"7(9=*.;;GF/<-==5=.&;<=:3B7/,'61B$4%5-,:3"-+=1..?6-78FF#>?5HH?-=>;(<":8@,45)H1HA#1B**37H@$
@r6724
TTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACNGCAATTTACCCGGTTTC
+
EF8-?+.E#E74G8<(B4C+@F)"0;$>93E/1A,-)="9.+((&G<6>198-2D!+'A(8@*%;.0A7:#%
@r6725
CTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCNTGCACTCTTCGATAGTCCAGCGATGGCGGTTATG
+
='9*83-),8C07=3"5>#.EAA-'9*+DC.%#'5)?G,)=2.&?5&1.2>=-./;GA)%->C4+$)'E'"7<7B52<%)5,2
@r6726
TNNTNGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCGANATGTTGATTTCCTGAAACGGGATATCATCAAAGCCATGA
+
#!#8F*))5&",?$@/#F<(<:&+3=#8<0"F9C0%A?A!:?(!G,,B#=;!8$8&8$"<,9=,4!%0((D9?&.!GE.)@28*;';2>>%GD?@+
@r6727
ATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACNGTG
+
0F(2%E3@/#%8>-=;!5#740(%?>-AA:1<$-@%&!8.
@r6728
TTTTTCAATAACATTATTGTTATACCAAATGTCANATCCTATAATCTGGTTTTTGTTTNTTTGAATAATAAATCTTAC
+
D504/>;C374B("2(?1GE5F>908GD@76,(5B45B$)>96+>4;:#:)B5B!#<:F$B!9.#>@C(.!C7HF9)&
@r6729
CTTATANCTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTG
+
</1,5G$>2:*).>::0"$GGC%52H>800:0#(CG)34@*4<:<0</<'3F$:'/F"0&.7"H;&>!HF7:C:,5B);6G<+H./9H7H*H:7G);H10H%'>D@6?7.<4.'@2H&.A
@r6730
GAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGANGCACGTCGCCTTAAAGCAATTT
+
0>1$5-*CG<)@$@$1.6>FHH#.8C%;D2A%+/>C0,,#.;."&>:7"7*D#!:#E312GCEHA
@r6731
ACGAAAAAATCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCA
+
7"+A%08A!-C#(A&C8-H4*5B'4C/*=16!="!(2#(9'$8H,
@r6732
ACATCACGGTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTN
+
.6'BG72+3D.65/<"855*A=7-E'6.,GHBD*2*=0>7;>/E!?<),
@r6733
TTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGNCGATGCAGCCAAAATTTGTGGCGGCGCAGAAAATGTTGTTAAAACAGAAACCCAGCAAAC
+
))$%+!(#""*+#'$$(&"))("$&)&#)($(&#$#*(+''+$('!!$""+()'!"#%##!'$)&*+$''(('%((*!)#'$&)$#%%++)"*!$)
@r6734
CGNGCCATNACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTATCGCCGTCTCCGAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCNTACCGGCATACAGCGCATCGCCGAGCAGAAATCGCTGAGCACATCCCACGCCTNACGCTGTGTGGTCAGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGTCGCAGTACTGGCCGAT
+
()!""*($#%$+$&%&$%#!%*!'$+(&$+)%!+*"%&$%+*$**'!%()%'%*'(*+&%+'++'+!$)"+(!'#(*)+!+'((%(&)))*%*%##"#"*')$!#!*')!(*!$*)''"&+)!)&&!"(!$)&$(+'(!##'!%+*$)'"#(+&$!"*%'%*"#$&"!!'&)%&)%&$%'+!%()!(#('%'%**(!&*"!%'"+""+"%"*&#!)$)#%)%!#!))'#&*)()()&"$!($#(*'$"*)*'(""%)$"'$***(&"())($&#)%&!#$"$("%%&)(!()"%+)%&"(++#+')+#$$+$$*#*+##(&)+"%))#&#)$'*)%#((*!$!&%'!""'"$"")+++$'(*'++'+*"*'"'%%#"*(*$$()*$*!+#
@r6735
TGCTTCCTTTACCCATNCCTCACGCTCCATAAATGACAAAACCGCCCGCANGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACA
+
>1,$*H3&=!!?1(@8@%3E."G).'BE(0C(H$:G#;$<+B.E?3!*/5*?;(11718'C)-0)2B!BDE.(29?,3*2C)'(G*#(:8(@;4,03!53E1EC80'!<=8#C;.H7D'<2DB<D3&??5C+?*A0/'EFF&.CB:)/(*6A.(G!><9-%@/0:H)-'44/4?
@r6736
NTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGT
+
6@<;B29(+,)0)B/#GG#G08G>H7B8.6!?">//B884
@r6737
GCCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACG
+
B@&,D1,GG7G(<>#:AA#>H*!0;+4?G$C;.(*-@GGC076=61%3(87>B8:9B0*&HHC)(?.9BA2H&+,C8/25((3#!<C%)?=2$&;@25$,!$/
@r6738
TAGCTGAAGGCCATATAACAACNAACCATGTCGCTGCCACTCG
+
:)@05!&B!G!,G5AG6?&GD7&)=1+3,+F&7H2BB>/%((H
@r6739
NTNCTGNACTTTTNACCTGCGACATACNGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCNAAGCTGGTCTTCAGCCNCCCAGGNCTTTTACTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTNCCTGCCGGTCAGTCAGCCCCCGGCTTTTCGC
+
!$!))%"&)$((*!(&+((%(("'"#$+**"##")%#*((*)%#"%%"("')"*(**&!%!+%$$$*&)%*"*""$*(**$'")*&&#!''*#!!#'(&%)&(%#!&!"%""*(!$+!'((+&''!$+$+%$%$($&%(&&%)("%%#&+$#((%'#!'&&'&)'%!()'''&%$($'%"($#+")%*+%&$"$)(!(&%'%+#$$"(&!#$'(+$$$!''"!!"#$'+(%$%%'
@r6740
GCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGG
+
46A)GAD=C/2&-:?"?6==0&%2<D?E-(H#-$&@#C*36D4?(%3'
@r6741
CTGTGATGCGATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCNAA
+
C#F'&8=B*A124.0):00'.4E:H$=96>=$9&E8C:?<(51%&+&3
@r6742
NCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCGCCGAGCAGANATCNCTGAGCACATCCCACGCCTTACGCTGT
+
'2<FH--?3"#H,1>.#<D1?/BF)?(#F"GH9,&((C;(!C&FC#$,7FC.+)%97@2DE&#C@B?@59D7"8%5>(3&%*E69'.1:0*HGB.6(0*3%0#10
@r6743
TGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACA
+
/::A54$0H((4E+2+:*F'D,F@B"*F83H<!B7A+GF!<70C7;0BF$
@r6744
ATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCT
+
FHH9@E*6=?&29(.=#:9%(?@);DB$$94A/G2@1$A(:&CD5)H!564$3H;.47+)?&"9@-C0!)13*2(
@r6745
NCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTGGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCC
+
"43;;,@.$G4-B#/:<CD/##4H$:H:9.E9AA?G*;.02*8;F1BB+/8'E'@G+5B#;09$/DA@=@!76HA4E@6DE+*6>2"!,,E?0)?154"(E2C8B<!D%)'"HH/3+)7'@86,B2.>*.B77'515(F2<,-C%#.G<@%2%=B<4927A1/"?&7A4D31
@r6746
GTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAANAGGCAGCAAAATCATCAGAAACGAACGCA
+
+!!"+$#!!&$$!%%#""'+!%'("*"$$$()*($$(&+)$'!"*(%*"#''+%'*+#("*&%*+!"+%#(##
@r6747
TTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATT
+
2D10!)+=.>F#.A>HD&FD>F:.2+@$#+,<39"+)C:D(:<B?'34H7947<9:G60"DC<4!D:6F93+6"#39.'<-:0-->?C2')$8DF8#0&5(*:<,7?$/BAH/&+4B2*G%*D;/(2#9&8-8@?"HD3G:F"0*=E=*'&+%!D$3H=*F?B+8)#8F6E9@!35(H'3;;?E@+<!3C&#
@r6748
CATGNANNNTNNCNGANCNNCTCTCAGTACNACTGGGGAATGAGTTGCAATTATTGCT
+
'**$)##"!'$$&#**'"(!)*!$%'+$(!#)")$'"&#)"&*&!&)*%"))!+(($*
@r6749
NGCCAGCATANNNNCNTCTGCAAACNTCGACCGTCTGCGCTTTACCTTCGG
+
$$)%#&'"!"$"&(!$+$&)"&#"+)"&%+!!+$%''#&&"#((+!))$)$
@r6750
AACTATTTTCCATGAAATACATTTTTGATCATTATTCGAATC
+
?@#<.@>+;@A64;HH<%,=7F<.341B8'0+-874CA2H9<
@r6751
ACGTTGAGCGAAAACGCACGTTTACCATGANGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACTGTT
+
2"?.C!9;/=5@@738/"<.!#FB>1(1>/H>HD-4."'$-&H#8B/:D=H$*266%127;G>*6?/@?,+07G1/
@r6752
TGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGC
+
CAG.1&E.4"?H13@H'!,AH@#'B0!06G4',EF1?C)A+H%>A>'EE0G:E:?8#B=<:%1"4&%@8'8FH'>@%H.%129B&6!";7!>@/B;7.C+:<
@r6753
AGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAA
+
9@#7EA?3/:,E)2DD.0*'.)#A#+11@#-4/.25)/DEH
@r6754
CTGACAACTTCCGCCATCATCCGGCGAANCCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCAGCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCTGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTNTCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCACGTATCGTTTNATCGGC
+
*+*&('("'$'((*(&&&+"*$#*+'#&*+$("!*#!)*'%(+"!)!#++"$#'&(++!+)$#%''#$&%&#"""%$#$+''#($&'"$+"'#)&"*"!%)*(##$&*'&%"+&**&#!"$#$!$&%#!'!$(%!*%$(&+*'$!)%&))(!+#+*&&*$)$'"*)")&%$'*&')&'!%%%')#*"(#'&'*+$'%$"+'*#&("*%(')&!#'$)&&$#(%+*"*&"!*'*"!+*)+#"#(&!)!'&)(#&!+%"$"')'"%
@r6755
GCATCAGCGTGGTCTGAGTGTGTTACAGAGGTNCGTCCGGGAACGGGCGTTTTAT
+
3<D)HF/B00%&C:&+E'<77.5*-4,6!"?F059-*?@77(+,.B&92@?%A6<
@r6756
TATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCNTAAAACAAAACC
+
;;("5()!A?:=#D>).!B6C*+5D*$$D$43%<:CA-B;3H,>&$(@-F)$D:;2D:/)>:7$.7:674-+"8EH(5)F+#C1D(@7,2#$7/<.3+?A>C+DC!!&(;*67AF;!7=$
@r6757
CGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAG
+
8+G433.2H<2E9,:B?&25!649(=&>4H32E%;%!,5*03@
@r6758
ACGGAAAGTGATGCGAAAAAAACAGCGGCAGTCNTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCNCCATGCGTATGC
+
-%;<-4DCG9'1E*#43;/@$7H8"%?G=?ED("21>@4A&8=%+@%<F)4A?0E0G--2'84/))&>88DD0'03DH.@2#"'BG$2A5>*D43DG40H%3$<*'&++,$A99C-6!
@r6759
CATCTGCCTTTACGGGGATTTNCAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGTGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGA
+
5:0?92C>,&A>;/45$,774HD!#H!)532-05?==7@8<-@-'19+'@A6;8H;@)152@$D'H<0?318D?!?)$E46!0#H)62;3??8*;8('0.,"H?G"-$B44DC
@r6760
AAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATNTTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGA
+
)%(&"**+**)&#$!++"(*#&&"+'$#)"%*%)(')")%'!)+&!&)&*#*)($#!'#$*+&#'+$!!++"$$%(++%"('&!(("&('+%
@r6761
TCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCANAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATNATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCNGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTT
+
'-G/;C-$&$"E%>61&;6%@<"&0.@+%3.#5@@<7?E38/%0>*9#<.+%#$9%7H&$E'6G,&==G45H&<//GG>?F!0*'GC+0:/&E::++=F5DA>#@)+;C9/B)?H0E'(;/'7&:&7!8G,'3.*=&?%0>>#@;>#=%/=,=C$34D2A%6A5.,!4H=(?+C4/5-?8))&F7F;:E:<@1(=/A3G;)EBG65=+:/G-/=$%F;GF69;@-?;(=;$CA<>(?*$&7=9?"(%HE<&?;(%=)H0*'$;;9FC?&
@r6762
TGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGC
+
%9*9"<1E!.E%32C432'1!>@D">>=!?HHE88-3'&5+1C#5&<3
@r6763
TGATCCTTTTACTCCTCCTNAAGAACAACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAATGCTG
+
(2H*!'(C4%1,.7)>!)H5-C329G&*(@>%B=D1,!?CE995:$@;0.1DC#9+;E'$!C4>C-=682C#;0=4',B;
@r6764
TTAANCANGGCCATANCNTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCANCCTGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCNGATACGGCT
+
'""'%%%#&'&'!)%$'#%*"((+'*''%!")#&()(%#&%#("+"'"')"$)&"##)"+&*%*+""+++#(&&$$!$"#(%*'#$'!%!%$*+)%')+'$)&&(*+"&#%!&'&&#$#&*))"(!$#*)*#!#'$*+')%*("+*
@r6765
CGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCNTTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAG
+
2,2<'#'1,=36$<!<*8(,C#::7BC7*(!9)#D2@?2FB?EC5>10*%@,9$9A7%0;<G!:28*%?70"-896A75/<5'%)>$8F7@?6H%'EC:1G-"!*A(G'<8F;C:3%7B?>!-+>81947-'4(+0!=H)G<;3H@>B.AC2>*
@r6766
TTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGNCGTGAGCGTTCCNCACGAGATACATGTTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTAC
+
?H-2A*9?F'$-,:&8)3E&B1A1&G2B5@:AF-!9*B:""?G)6FE7(!-<(CB9'A(&>5%'F1*$.@E2&'E$*=!9-2@+2F)D8?G94=(#-%,/6H"/48G45+8#3#"H01D%;&%;.7/)$5991C%F%2CD3*<+'>2G269)D2.3'B("6+!::BD1,8E=
@r6767
GATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGAGTGCTC
+
0)2%>8/#E((6:>*#7%=!H3/F=@HH#'/.7.?A%F1B5,#.4AFG/?5@!H3'?G/
@r6768
ANTNCNANCGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAAT
+
)"$!'(#!*+"*)#++$$)$!))%")%"$&!)+$!&&*#"($%
@r6769
CGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGCCTGAGTGTTCCCCAGCACCATCGTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTACTGTCC
+
FC;;,=;@$&=7C?=HD=)=E5C?-(03<-8):)::''=8@&9A9-4+?(?$(">8#H+%;E&2.#F*.59%:41>EF",8)<B<@+<A(30<=:4.$E=6%H20?:2.+=6G?<H+&%,.E8C
@r6770
TGTGCAGNAACCANGATTGCAATCCTGATTGCTGCCTTGACGTTT
+
&"&(*()#$$'&)'+'((&%!'!#$$&!'#$(')()""*##'!%!
@r6771
NGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATNGTGCAGAAATGTCGATATCCCGTATCTGCTGGGATACTGGCG
+
$2)A76.DH>)+G&FB:C;D82=="#"FEHBH/FA)(AH7GB&)'$82+:E41'0?95F*HG300+<BH(68"/GH)%"%-?1-),D7'DH!B.4D
@r6772
ACACAACCNGNNNACNGTTNACGGCAAATGAGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATC
+
#$'((%!$$!!!"'%'""(##()++'('+)%+!!)"!+%"&$())"*)$(!#*#)*%%)%$%!#!&%!)("$*%"+#&'$%"()'&+('$$*
@r6773
CCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATCATAC
+
9'!>#.BHH&.GC85F6F<>()54;C")C!>>B)=#D1?HGB,(5+(++':#)//-H!0*@+F.8'+((E,EA<"!B-+."A>+0?*!#0G$A(
@r6774
TCCNGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTCTCTGTACTGTTGCCACCCGTTTACCTGTCATCAGGTCATGCAGTGCCGCACGGGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACGGGCGTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCANCA
+
$2<=#BD"87-3E9A<1(@E=<81.'-*6F&2+'>$!/<4+A;':873>4AA3?.78>E*$<'.HB*2<A5C'0%6A>F)8D-4#D8:).<'5C:1&AB87>0)))?09E.@3<@*H7D8H?@F2395%2%B5/B%;E29930/*"!5#$C$=(4<311&!?HE89EC22C+8-%E$'"):>)(3H-BH;-3"8#3?$G2"+1*<1?=-6>-6*(=4-,/1-"3189.%8$AE9*A>49/
@r6775
GAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGANGGTTTCTAACCTGTA
+
@9)?>B>E>'632F&B:@4A&??H-F,/7D,(2!-744)<F+D:=05/+@H4/')#*$?!75'H,1.7$BH.73B7+'%(H&@?F49D'-5A%C,(*7#$","3C431A@$&G(=;92A<<@:0B
@r6776
CGCCGGGTAACTCACGGGGTATCCATGTCCTTTTCTGCGGCATCCAGCCAGGATACCCGNCCTCGCTGACGTAATATCCCAGCGTCGCACC
+
83!??,!8*:B0.@)#H+/B(3'.()*D5C#$*-6?0A2,E"BB?)/$$A0BH2G/38GD+FA+4CH."79A2)%2?C<)7D+7>4D/C#*
@r6777
GTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGAC
+
.BD,H2E>4CA&0$:!(!GH$-2"218#2/#!?86B@?/7.2:2,2>F!)(;GF!DH-0.;A<=)A-E!6$>7#2'3*F-42;5&:0@).@2<"=@-D.?3E1.;G%E(!!@G#BE!B.H-G@:0D;2B7=@7#19%!
@r6778
GAATATACCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAA
+
0%?%:52)7<F;&9&;3+9)$>;%'6>19H)0"-:(/1+@$E7@4$5@:"(8--
@r6779
GNTNNGTTCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTGTGGCGTAACCATCATCGAGATCTGCCANATTACCCTCCTG
+
(#%!!("+#!'"$!('#%$&""$'*(+)())'##*%$*!&!#!*)!#$)#$$$+&!$(!+&)+''"'"&+$#'()#!+''$)!$&(*
@r6780
CTGATCACCACTCTTCGCCAGACGGCATTTAAAGGTGATGCCAGCGATGCGCAGTTCATCGCATTACTGATNGTTGCCAACCAGTACGGCCTTAATCCGTGGACGAAAGAAATTTACGCCTTTCCTGATAAGCAGAATGGCATCGTTCCGGTGGTGGNCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTAACCGAATGGATGGATGAATGCC
+
)<3#+>)$G'&%+?->B;E,8":4?F!145B;&()6/,/401/A$!&:.C.&+7(E"+CBD<!3%.+/7>?:4%6->(#78,?&"=7AF%;/%=E4,"2;+3/*,941%*4CG&;3)*)1F14+1-)!3/A>%=571=EH5G,')G'7=:H6=EB.7#9G?.-#?;EB9*DH5FF3>/$7(G#4=H8<2+D&!C&1'*&GC?A,%3B.C-;H*E//,AAF/$H683%'$6F205C+;!)C=5A"?01$'>,&'1'HE+>@'@A6E1E+F:A9#'E%/-:5-4;"!C%;-H&5$D@>%.EBH@*,
@r6781
AGATAACAATNGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTTATCGT
+
3#G-DBB%,!7*F-G&%",<&3)<E).'-AG<?!5G+=D!"!%<G#)G..,8C%G#20F'?4(D2:8.&)C6>:2@<B+G9%'F>(&/3.E:!7&;6D*.8+D/&!9*+!73CAHF?("5>F5'%C-%7>'.7BH5)E:"4+7=D&#3&.;7>#85C4#B?&*!@#.->@/
@r6782
CTNNTCCNGNTACAAGTTNNNGCGAANTGCTTAATNAATGCTCGGAAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTAGACANGTCAGNTATTTACCTACNACAGGACACACCCTCTTGAGCC
+
*&&)"*'$'%!"!("#(!!!%%'%%#$)(++(&%(&#'"()%%&)(''+$&""%)!%!%)"("#')#")#+''"+#(&$"""#%)(*!!!#&$&+'&!&#(+"*'!")*&$+#"'+"!%*$+'+&&"%*&)%&%*%#!")%##!&&#+'!%('$#)*##&%+(+'!"+((#'%"$(#!#*)
@r6783
CACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGC
+
4ED#235'!-+'&;=>2F4)A"<$(@C9-:347G1;.>8(=:1=0"G=4**5-$-(41";15
@r6784
CTCNGAACTCCATCTGGATTNGTTCAGAACGCTCGGTTGCCG
+
,::9-#B-71)A?&&5@".F>77F#,?.=1'/.<2'A:A&-;
@r6785
TATCGCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCAT
+
,='$(9A&:*>9;)/@H+*F">!GG#GD$%22HA5!.5-*
@r6786
TGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATCCAGTTCACCTCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCT
+
G(H3&4,5C%$5.@6%2)-5A.E><5=%#7--'(H7"84>1#A>F>G'918B5G4E3)328(G;4>..0B=:/9@/HEA;+DD0+C4
@r6787
TTCCAGTTGNTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCAC
+
6B(;B*E9<@=0/C(7G7:"A788$7+@G?:7<.8"6*H!:084+0(81G(E#17
@r6788
ATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTNCAAGTAAAGATTCGGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATATTGCATGGTGNGCTCCTTATNTATACATAACGAAANACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATC
+
G&77)&B$5-54;<AC#'3'.0(!@H=8/'D.(7B,@"6D6C(.@80%=+B6/'@A2E*&4"?5&!=5C<=9%;#2=:4FB9/-,3*<#5%+)54H@18/A+/2F+/:&5/D<.1"CC6!(&B$.5<'*:B!?!"52=0H*66EF"?0?-;$>07A=1#G?F((E>9;/7'*77A0"#)-::1(5.D0CG)0;886G:-:-A>5$='HG2
@r6789
NAGTTTCGTTTAGTGCATTTGATCCTTTTACTCCTCCTAAAGAACAACCTGACCCAGCAAAAGGTACA
+
"1E2;;HH*,%:12$B"7-*C+)/43+/#9#3D!@(-;*B015A"$10E:6'EC<G(+HF9H0@!"((
@r6790
AGACTCNCNGTCNCNCNNATGANNNNNGNNTNGAAATANTAAGNNGNNGANNCTANTNTAACNTTAANTNNGAANTTANC
+
$!!$#$#!"#"##!!#!#$$$#$""!!#!!$$#""$!#!!!#$"!$#!!$!$#"#$""$"$!!!!"##$!"$$$"$#!"#
@r6791
TATTTTCGATCGCTTGTTTCAGTTTCGTTTAGTGCNTTTGATCCTTTTACTCCTCCTAAAGAACAACCTG
+
AF?;<%0G-#4.;,,B1*$#CA@)@5G,$,G#6/@'$$4$7<428'.,$%*<B"EH'23*;AF,E!$.8#
@r6792
TATTNGNGGTANGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCA
+
*%#'%'!*((%"*")&+!*')*#%)+!'$"+&!'!#"!##'!('!*((%)(*!'!+
@r6793
ATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCA
+
>;"B*/@<""05(;7C,6;F=DE4?>0"=12<--40G2G3D$332(!8E546@*6&7'GA9/G?=0CC68;C
@r6794
GAAGACTCCTCTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTNGTAACTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGT
+
0G4!@.F309A:F!)?HD11H!:1914;?.1A!#=E+:18;1$(!.8F;B5%$8:%<4;?)E(3A=94C9#C:*/B',;G>%6;E!2"1E+=0D46898&B2;?GG=&30<9602?D69*!
@r6795
NTTAGAGAAGTATTCGATCAAGTGCNAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTAG
+
$&**%&$+*&&&&(%)"*(%'&#&#)$(!)*+$+#'%!'+"&%"("%*("')+&'#'&)"&!'$!%('("*&&&+!$&'+$#)"%""'!*&"$'"**#'!
@r6796
AAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCC
+
,E,861C"='=DCD''.59)9$3G&8@>,?D5EGA0#7>5-B9:@63*6CE$!9.2"49'&-8E?6F82?"+<.,#GF-@$+E.?E0/
@r6797
GCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTTATAGTTCGACNGCACCTGCA
+
GH%D4=D?)+7?H2>G:EA.9B?%'H:.G9<>.H(AD-)6")=C0FCA*:3H<'B3A+3?@('-)37!@*.BG'!)B:?#
@r6798
AANTTCATATAAAAAACATACAGATAACCANCTGCGGTGATAAATTACCTCTGGCGGTGTTGACATNAATACCACTGGCGGTGANACTGANCA
+
*&*5,<279#7D<&*D(A/=!?=F@5H;2)BF=7C>$C/H.CA1";8".:F6'%&4H=2,+11?>$/F14)G=)G.F-4?!8-'5$1%F$D4+
@r6799
CAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATCAGATCAACACTGAGCGATGCA
+
G>8'&'?*!A6103.B<#DF;.-G;!%6;/3/@6.+'*1)B+>79%G#=H'?<;5/H@A*%='A691+#D07!;&!;$E.("93DDA'.!"A*D2*$;?G9/C+19<'9#;)3((*9@AG!#$AE*2-()+.%78,>*.A8@*"+*;A7,
@r6800
GTATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATGGCACCGACGCACACACT
+
)B"G/>H40%A;";G%:<2*F74@:--!!C-3D88;%FB)%4+167$-+C;;DCC+96A3'H?
@r6801
TGAAGAACTGCGGCAGGCCAGNGNGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGA
+
7!4,;E!E8<66<!,/@E(382F+;%->$(17<A&>'A!*&$/-@!<F!!8599-;/'H/3>A*F7!%B(FA,!E?0:F))/&=@,G?@,G3<@?;B<(%+,.A
@r6802
AGAAGGGCTTCGCCATGTACCGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTANACCGTGANATC
+
A"A:;G6+("?%6,:3?)=$A)3.7GB8!#432%7+=+)F:24>?"FG%HG30C@3,HFG;+F/%E1'=#;"%0/.*5?4:?,*/7%HD8=@;5-19<8HGB@*@H!D>?0)17*?E>58?6;3)A@-A>
@r6803
CANTNNNGANNNNNNNGGTNTCNANGNGNAACNNNNNCNGCANNCNGNTNCNNGNNNTCNANANNGGNNTANNNNNNNANTNACGNGNNTNGNCTNANNAGGGCGACGNNNGGNNNCNNNNNACNCNTCANANCCNCACAAGNCNNNCCCGCGNTTGNNNNNCNCGAANNTNNTAGGACNGNGNANGNGGGNNANNG
+
#$!"!"#$#"$!$!"!!!#""#""#$#$$!!#"#!!!#!#!#!#$#!!$$#!!#"$#$#""#$#!#!!#$!!$"!$#!!"$$"!#!"$##!#!!"!!!!"##"#$!#$"$#$#!!!#"#$"#!"!#$!#"#$!$"#!$$!#$!!$$###!#"$!$#"#!###$"$"!$!###"$$"#"!#"!!#$$"$"###$#"!!
@r6804
NGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGT
+
&/3#$C9;1+@7:$5$E74)FF.>A,%@BDC"'9?**E=1.4HCH;()3=
@r6805
GGCTTTGAAGGAACGGAACAGCGCCCAGCCTTTCGGNTCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCG
+
H?%<'E6E8G?0G%!%;+-8>$(6-B*2?&0F,/F-;-#2&B#,=C;1'C?A'0#@/103H35<02-0.)G"="F2D8G
@r6806
ANCGTCGACGGCTTCACGAAACNTCTTTTCATCGCCAATAAAAGTGNCGATAGTGAATTTAGTCTGGGTAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCGGAAGGGCAGCCA
+
'#D#'244=4@21(A,7##8G87*!24+5@0*7C5>:1E2786C&'+:="%.C+6)F)&4A5=D,)25'A:CC5&)4&.C728@7D!AB!FG%>2C3&G5=:D-:!G&8<@26:)!F@:@:;G!C6G>'<34*4@2(B-$6.*B%(,EC@/4#-2FG(;B#H1G)/2:G-4:5&B@C>FH05-GA-3>,48
@r6807
GGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAATTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCNCGGTACGCTGCAGGATAATGTCCGGTGTCTTGCTGCCACCTTCTGCT
+
4>BD-F+<1<+.(H>;51:1F6A1),F4$<61,0%E/&$94+C*-!*<9'C-D9+-H)F%;&/3D?9*/7=1F/:<?F>"+@+6B$<0*+E7!"9?F/?'7-;07@G!C0!4$%H<-"F$09>1$.2@%0,?)E+%.4E#@.6C,H9E<.*23B'7*?E#<>H1)?+0*G96.;426)?@&F(&
@r6808
CTGCAGAACGTCAGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATTAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCAGCNTGACAC
+
D6",+&DD&!:H0?+H';"2G1<86!<2'D?3<$29>/D1BCA*F<0F$E=%D)><F0,0+'6$7"#6B$1@F!F">79H,99.8<-(5!&F<=#E+'B'/4&F0296F0$*07H=,AH7;'81+!C=@&8&$--0;-7-AE=:@,!17A&7>A#G)+.2G,HAH-A?'8<<F9B!)6*A9>663FC1#!94");G48(>B)@+26"/@E($6?%6E2.'($31/&6=#+*F9;-)
@r6809
CGCGCAGGAGATGCTGATTAAGGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGC
+
2:=FH+53&C,3H$(/0&2)/2(H0/,2A&D><)6*(+6G5795DF3DF=4?5-%,#:'?;<D*H&->/39BA#@=(/)C'>@EE+<?=*$9*+D@
@r6810
TATCTCCCGAAAGAATCCGCATACCAGGAAGGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAGTGCGANGGGCAGCGACTACA
+
0E=693*>AD+,'HH29F>HD76?.%*7$F1.?"<!F<(/0@>/8C)4-;2+9'F<6*=-*"<.$F9+#+G/4@FA=@C8#0>BA+1<2?D
@r6811
TNCTNTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAA
+
*$DG)/;:?#;DD@.!4G.$?:7&=GF#8:9%+D"?A%*(+=<*$<-D(3733
@r6812
GGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCNTACCGATTTCGGTAAGNTAAACCCCGTTTTTGTTTCGCTTACGTGNCCTGCTGGCCACCGGCTTTCC
+
,=%%,;8!-$5(1+-?F#6:(8:&+<E(/9C(4=!:1!+#$%$+G09$4?6>!((>(><:%"=-1H)0EC5//1?:H(>1(4**0$6+1*$E&<ED02E1%*(E/;>$;9BEF'CD%B)&D?F"5D&
@r6813
GATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGANCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGT
+
0*6;>A+C?F&'0G1"0$!AF%*@H$@F&@9:AF*6+(3H,<.4(%(&,;+4)4A'E';E*@#&H)95)5;>&A#7)<%(B2&)AA@DC7'2H$!#/)B!'+@318B"<$+()%=2!#%##6F8H;3*2D8%'<!%G3@D4;8A2.%5H0A%#)';F;*%+'+?$*2!1.
@r6814
CCACATGCTGCACTGCACCTGGGCCATGTAAGCTGACTTTAT
+
1CC<H?853#H9)G$=<;."0%"55#+9/4$25:+H#3C&11
@r6815
AGAGGAAAAACTTCACCAGATTAATAATTTCTGNTCAGACTCTGAATACNGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCG
+
7!>?),14"*/52'2>++8/&@"5A6%685;-@.62F$:E??%0:<B/-<4>&3"=*E:!?5>@7#HD:A%6!,@::8.FHC3H2!G'.?>C7=.44C"A
@r6816
CCTATATCACCACAAAATGGACATTTTTCACCTGATGAAACAAGCATGTCATCGTAATATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGC
+
=0!0$D&0C7C1(>-..1G64@<H802->H:15%8'*'/6%49*,=>?DE&*2H1HCH(<@?(&41D>>32F=8?&@*&G=B8>426>FG*H'.=2:G65G.G>:C9/3:&G?GB13@#2$B?D#1=2F1@A":E*76%2=D9-%3/8%+99@'0"H%8:"-#8%%,("<)G!@=&+CF.D$5".;6C+9:9B9-"BD*+1#E7)>3:9"=&<@@+1'<=80;9.$A9063A6211!B%A2./,B<82A(D?.(?38,F!F*/C%,:92=B=+3&6
@r6817
AGTTTTATTCGATGAACCAGAGGTTCATCTGCATCCACCTTTGCTCTCTGCTTTTTTACGAACATTAAGCGACTTACTCGATGCACGCAATGGTGTAGCAAT
+
(6>0+=/?7;%?,D83@=2!,%10.)E354+G@#1-3=B"G3E0G%!4&+C(0#=7A7AA=*+GD=".G1.0=3'3:G.7:2E/-3FC&<132//'G?-)26
@r6818
GTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCA
+
F#H0&>AA($<;22HD)??=@F#2CE6-&83?640*<.;B
@r6819
GCAACNGGNCNTTTTTTGTTTCTTCCGCCTCCCNGATCCGGAACAGTTTTTCTGCTTCCGGATCCTTCACCCAGGCTGTGCCGTTCC
+
%*)"!$%(!%+("%)#+%#$)'%+%!(#$+%%#(")!*)!*!*))&*!+*"#%#&()$#(&+))))$%&*$!!+'$$')$&#+(#('
@r6820
TGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTC
+
4D.137,$5#<.;'/4053<F(3C01!-@B;1054A#4=8/0%E,H2#$6(8;4,A'C0@'/4@6/+E0$:35*/;C%E<9=9;.$;>2=*C(D?G9-=/)..<3"*$
@r6821
AAATACAGGTAGCTTGGCTTCTACCTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGNTGGTTCCCCTCATCAGNGGCTCTATCTGAACG
+
9%?F*";'2!C?G8.7<.B',!43F>DF$(??>@9/$@E3<,/3%#@/%;:,3">(35E4+0//>3AA72%<93/'1<F<C"#FE8,(<"G>1),-7%#H".-6DB
@r6822
CTTGGAACTGAGAAGACNGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTTGATTGACGCGCCAAGTTGCTGCGNTTCTCACCATTAAAAAACGCCCGGCGGCANCCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGANGTAACTTTGCCGGACAGGAGCGTAATG
+
)EF@F;1,H729#(;H)+<*"4A<0?0/1GG*F8>=":75AH<,1BF*$D>@#BBCFE)9A/B6608:@@"B:0D5"F?:@)';-D+1,4),"*A.4<+*)/114H.!AA"+0!D"$4C39<(2-3?7817:--,$17C2F0E1,':(A&&/A20A/F40,7.#(E<?.)442<=B:%8)&(0&B*@<E&G&<!'37"6G49A(;,:(*+>@15()-B?A8=E6+.-;%&0@@,>'$-7*C)FA.B*EB.E:-&9F'C)@=$1+@4G<G>2-&DB8C*H7AH7DA83(,?6GB4E&D!">+(A77>&0,35-?%'DD?(,G
@r6823
NTTCCNCGANTTCCCCAAACCCAGCATGCATACCTTTCCG
+
%!$")!+(!$'%&!%!&*+#"#'(!!&#!)+*&$$+#+%&
@r6824
GCATCCGGNACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACA
+
5G%@36'85CC(41<5=6C(',4:=C$(C*E%"A81)$-0E)/"=F-5>?=<()23;3*(
@r6825
CGCTTTCTGTGCAGNCAGCGCCTGTCGGNTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCTTCTGCTCGTCAAATCTGGCCGCATCCA
+
>3%E+(+&)ABH3,&C(A(;/A-G"$555118/:@"BA!?/C##5?*3$?A391$$!$.#/"<%(?A50'**"E8#2>>#:)$5F/2GA25!.1=-D?;9=F;B0*$B))##44,;+;="63(?*+@"'@+7E9
@r6826
GAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATTTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATGATGGTGGCGAAAGC
+
5(,"GHGDB,.#'4'52!;,.9><"*G$(!=9:'G.1;:"'+<*)<1<:9."61,9!,?14!0;7#:4AB.*+5*&;A<?B87H'A/:E#"@?$:B$
@r6827
ANANGTGANTAACCCCAATATTACATAACAATCCNCGCACTCGCGG
+
&%&$*+(+&+$#"&&*!)$&#!()!(')'!+&*(#$!")#+(%!$(
@r6828
CGNTTTTAAAACGGTTNGACCTTCTAATCCTATCTGACCATTATAATTTTTNAGAATGGTTTCATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGAT
+
<H*&,7"'5G>4*G2-0)3(@-5.650:3:?"CG?:HGG>$#B/E+A95&H(562CAH:91<-;65HB2-?06@%(G4?=994<7!G%0E8?+1C1E9!88)*'2B0"5)E-6729B7E/%5)@A</C!(!/";$2%73%($3&'!%,8$$(#9A0&'>5<9'BFA<6EE136?.*.->$)@/C2,H(8*HC
@r6829
GTCGTTGAACAGTCGCTGAGCCGACAGGCGCTGGCTGCACAGAAAGCGGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCAC
+
2?*#+"F9!)7+H1.G&#.8G2,/'?C9&110,:++E=@D@4D1(5,-!<3##G+G!3,9:.1+B337/#>99C=!<.C**%%17,0/>4-(%#EA=
@r6830
CNACTTATCGCGGAGTTTGGCCGGGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTCNCCATGTCAAACATCCACTCTGCGGCGGTCAGGTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGNTTCAC
+
(*+")(%'%$+"$"+(%)&"(%"+$"!+"+!"+$*!"&&#%'(%$+&&+%!)(!&%)(&#"$+("&%**&%%$&!+"*"%"%&&&$#+"#)*"%$"'*!%&*#"*"+#(#")('+#!$+#*%")("$%+(&+'"$$%*#$&'##)!$+*+"*)")"$!$%&'$'(#*%!&%!'&+&%&**)"$"#'()&+#(*')&((*"")+$)&##''()'!(%$)$*!&*"*+&+&#&%))*%"$(+()))('!&$'#%"+'"!'(!&((%'#$
@r6831
GAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTTCAAT
+
?C=B9,717?AC1,;-5D;H8G)7&-5>%(15#'?##,<&E.@B8#F)#(208")?;!>0BE8"?&F2E6,,C6!0"-6'.FB#&8(13&34'!G2=:10!8*.=@9-5@#5!8A#"H(
@r6832
ATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTNGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATA
+
-%&>@G=E7D>5?!@E*E=$$#4,CA$-:E7:640.8A$1C02-0A1.0%:@B#?&;)*-?"145<FA69)'<(*D)<>?/,,8>#+A.2#1.6'#!D8+$#@C!8+GE1B+DC0("&
@r6833
CAGGANTGTAGTGGCGGAAAAGGAGATAGNAAATGCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTGTT
+
,B%,*E(A'5$'0FE5.,"--(;.:<7"-'?#BH'7#(.8>++B#>)).87BF0:1";,1,+()).C7/*?*23@F1'F;%:'-03!A
@r6834
GTTGCATGGGATGGCACCACCGACGGTGCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTAC
+
,24@*2=;;C;@>5)'?CE@:$.!G,(.FG/H+6E1+500#B9$-'#1?H/D"?B<=EG5@C95H)?*&%4:8F9G%-A8.CC3(2C
@r6835
GGGGGACACAAAAGACACTATCACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACNGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTG
+
,C(.52;56@2'%8.,8C?F??H>+C@?<5CE,#8)3-*#295(!E"<-4@$@D9F+)>3.HDD5-67#"()5BA50B"GE6>E!':/GE4"%)0,!G?3/&C''4?=/.+780%4D,2F96@'=)0=3&*D-"8146==*).532=3A?/C:*2
@r6836
GGCGCTGCTGGCTGATTTTCTCATTTGCTCCGGCATGCTTC
+
E$1DC/DF5*$2F-7+?).A+#.>"G4D?0A&A)28*2$-:
@r6837
AAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGG
+
CDC9,(D8!:)D*HC#,2C$E79(/)32(.7D>:>99+<%@;%!3-#1&43C-50?.!/7H(>838/%#=&404
@r6838
TTGTCGAGAAAGAGTGCGGANGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGTAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGAACCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTCTGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCCATCGCAGACAACATNTTGAATGCGGTCACA
+
;/,!>@/.1$G:#0C-56G?.%54DH53;7-.-+=$B7#8'18$?(+64,F'+0,?:0+-5=./,93?ED1H:%;@@";"EF2H/A:>&0:A=(B5:;FA7$7*(;;%>,6<E#,$?7?,19GF-7?<3%0(F=!?G1-+@7B$&"4FF:.B*3"1=!'.*?;,6>GGB(@E.@/5'74)&@>*,)0)5DA+@=;C399%$@D*2>
@r6839
TGCTGGCGGCGCGTGCTGAGTCAGTTGCATCAGTGACAAGGNCCGGCGACC
+
AH>+!9.D6C;154B)/'&1)&>+1$:;?FB@D97H..9&'DD&4G+%"2F
@r6840
GACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTG
+
<-:ABG<?C:)/#*,#/@HH>228?.>3870+6%#1(GD024$60-"!C$"$>7>B7;"E9(F98%E/2AF=B0
@r6841
AGANGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACG
+
"(("+$*!'!#%!+("!$$$"+'"#+)'#*#$&&#!'&$%$"&'!)&%+
@r6842
TTCTTGGACGTCGCTGGCGTGCGTTCAACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAA
+
*A'*1(#&:>6D.@//:<1:)B*A&/%A,+&,:E68?+-8&@:!,D5D!A+<?G$206E7*"%#0
@r6843
CAGATGGATGCACAAACACGCCGCCGCGAACGTCGCGCAGAGAA
+
F;1,D5,,/.6GH&*#(5H*<(:C'A29*$258+14+5,29A"A
@r6844
AGGGGATGAACCGCTTCCCGNTGCCGTTCACTTCCCGACTAACCCGGATATTTTTG
+
(%)+')!&$)"+"$&&%$'"#!)&""$('$$"'!$"&")#')))")'%"$%"!#'"
@r6845
NGATGTTNANCATTAGCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACANAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATNCGTCAGCGTGATGTTGCTGCGGTCGATGCNANATACACGAAGGAGTTAGCTGATGCT
+
#*')'*)(%!**(#%!+#%+*(+$#(&('$$&("(!'(*'&#!$$%($%"*#*)#)$"$*)$"()+$$(*#$*)#$$(!)%*)+)+'!'#&""!"&($%(&#!'$$#!**$)()$!($%*%'#"&('')$*%(%*)*$#'*%$#(#&##!!!*))+*+('&&)
@r6846
CTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCNTTGCTCACCAGTTCGATGATTAAT
+
.GFAB>(DB$$71#F#%F098"(<&E1H=+HD<2F%@4/.(G*224C834F8.4,85''80AD)(*?&:E2+CCE?6*E$-'348!0#"
@r6847
CNNGNGCNNCACGATGCAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGA
+
$(##!&(%!+$!!+#$'*&)(++%%$&+"(!%$"+'%'')"%&%!+'+'!)"%#%#$%!%'
@r6848
GTGGTGTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGNTCCAGCCCGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGC
+
5E+*3)!&(01G194@7G0+&!*5A0;6EF(?*5+<9=-//6EG<5-*0-H;*!,$"90B%'.;;#*33<A-7<9(/6")8H=923??F5*CF:?C@F+C*&(F)
@r6849
ATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGAAT
+
6EH!?G5?!;H6>7-'A-=)4E:D'9G@G'?:53%A#@CA(8.G7HE*%+=0?)<=!;3<90A&F,0.>EA#)$B@/2>
@r6850
GANATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAACCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCNAAGGCTTTCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTGGCCGTCTCCCA
+
)*%+)%($#&($++())##%*(#*%&&)""#!%'+&%$($"**!$+$(%"'+$&!&+'(""+*($'"#*'"&++$%*!)#"&$+(&)(!+&%("!&($&+#"$**(&)%**&#$'*#"!*$&##$%(($*'"$+)"'!#+'(!+*%)&%"+!)(!)'##+*"&++
@r6851
NGGACNTNAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCNGCGTCATGATGGCTCACA
+
#"!&#!)'*+++&%)$*&'"&)'($)*($()#(('$&"*#&())'(&++*'%(!"'"&+""*(%*($(!"++)&$!%'(%+(#"!!!$$!&'&(*)%!#"&"#%+
@r6852
NTGCCCAGCAGGTCCGTGAACCGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGGGCTGCGACAATCAACAGAGGAGNAGAAGAGTGACAGCAGAGCTGCGTAATCTCCCGCAT
+
&+:/'G?,!9!F2G@F=<F*+(G@:F@9+'F*'EAB+/>+6G,3"D63$)6%B%>)=@2/='&#1;E24:DDE!-8'+=>79..+-DH(9<664801;807B6?F.:84%"EE<F#,49F7=G+C,:DH90F:CD5."@CBEH<
@r6853
TTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGA
+
F;C*27G4#+0%)+:#GD#49A4&,C4.FGG4.<7+D5454C9=(!!/9?3
@r6854
TGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGCCAGATGTATGTAAGGCCAACGTGGTCAAATNTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCTAGANGAAGAGCAAGCGCATGGNGCGACAAAATGAATAAAGAACAAT
+
D;?-7+":E'HH:F<-=9?#C<D95!@!!)F@41,A6='*!<979B&A"+7G/1!7072;4(+>7$G-86@"8F%"A)'3/2&'49;1(;)#;"=E+4/;G:3C&(=E)B)"?79*0$&1&(.8&;7A*=C28!HC@C,*7:%1C5;C4<"F?>*F)#'6*/G.(6*.6D#0-#H</!@..,6A#@<)9)<5#'(@B*+:D9B46C=A@@:=6
@r6855
AGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTC
+
G'D=G>(0G=>%&F!>B5F2%B#"EG@:+&B3$?7?/#+31858')04@>)&2=884AF3<(.6>=-1,(<'))2%=D!-3(&A*.8/!/-D!$=320)?6"$?B<F3
@r6856
TTNAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGTTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGTCGGCAGGTTACCCATCACCACNGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTT
+
>H#5@D*#1%,.7=8)B2)54F/5-$F=#B5+7"5*1'G/>%HB<+(*1A$F1'5(14CE1+-))(CG1AA-7()(D+,/6)=!40(-G89/D)1+$'06A/?+:<<?G*F4E,-E>>1"6!*526"#,)C/7;E'6:E+0&E:)EE*;&)C=96=/>5G)8!$
@r6857
TCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATAACGCCCNATCTTTTTGCTCAGACTCTA
+
?%GG3?8)?1H"18831-#$<GH4+>D6,5?H)<4265/6+??F"1F,";)A4F#G$?:/$#(9<#5=
@r6858
TGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCACGAATATCTNGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTNAATAAATGCGATACGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTTGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTT
+
618?))(;-0'#B*1*&0*$+!#1BF(;&<!2'%$B*0C-)A253<4@0$=A52&<EG42'(3304&G+E7F:;#1!)H+*?3D#6:+6#,:'$*>;"*@?)H>1G?)<6D6:23F!G#'179%22'+13:;96F5C.$&HC*#E$?8-6(%:6<'"8/C(5.53E.;E=CF.,GC:,,-#?)??$AE+2>@=66=#'#>D-9',A!H<7):91<8E3G/&G1)8A<@G48:
@r6859
TCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAAT
+
4G3($,;F?B&=+%$'-3$@F>&AD%(7$5.G();G6E7FHE%&.0AA!HG>507,'!<B%10C/2
@r6860
TACGNAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCT
+
<86.F9>0"<A(6(G)#.A$.;*5#:*+4>:A"C6:>E5G7)"'A=;.<:HAD=CAG"-A2;#DEC9.-GHGB5&>E>,&A4&.7(<)780,=(=&/#'$'/$&GH@.:AG?',"9;!66D!>;<>D*G9/1B(C+5(%&
@r6861
ANAAATAAACCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTACACGGCTCACCTGTGGGATATCCGG
+
806<3#B8?3B!D>:FG4'=F9:05;'"#*8%CA=)C(;6:<;E4$9D+$;?!,8GB!?;(AF00*:,0>5-8+14))
@r6862
GNGGTNCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGGTGCTGCGGCCAGAATGCGGCGGTCCGTTT
+
'!+*(%)"#%++)!''&$''"$'($+$&()&'%$!"&&!$%$"#'!#$)&%#'*'"&"!'+$)&%)($$&**"()&#!)$"$(&&&+&$#'")++*
@r6863
NCANCACATAAAAAAATNCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTG
+
###&**+!%)&$#####"&%(&!(()%&(%%"&"!'!'"#(()'#''&+%%($'!'!!!$*"!+((#++$'%))*
@r6864
AGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAA
+
1B!?010?AG;1-08(.H=F.-F*"/2/=@:)H9.)F?8;A<836=#F&@"0B.!9(36G8#-:G
@r6865
CCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAA
+
8-:4>+.2&&871C0C-F)?D'B)!+03"C&G"=6E+42G8<+.'G(;C0C
@r6866
TTCGTCATACACTGAAATNATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGG
+
"+'$++"#'$)&)#!$+#+(#!'+#(+'+&*(*&')!&'"*$&#(($"'($#+&%&!"+#("#(#*$)*"(&)+)!)(*"&%('(&"'&!)&#!*+!&
@r6867
TGTGCAGATCCGGTGTCTTGTCTCCANGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAA
+
'H:/850$7:2AGH>:%41552*<E;6C:%#G0F"64"4G1:F#7>):/##59#&-2G').=<>30:(E7C)#HBEH2*(2C8F!=.@/.)3D$+DG
@r6868
NACAGGGAGAAGGCGCATGAGNCTCGAAAGCGTAGCTAAATT
+
!%-4"+67>?F/*9@8+:38>*'&&+%!'!E#C%@FB%>F9D
@r6869
NGCNNNNGNTGATCGGGGATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTNTGGCGACGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCANCAAGCAGGGTGTGGAAGTAGGACA
+
&))!"'!!")##%*+%"%!"&!#!"%&**+)))*+!%%))'!"($&$"*&*&+$!!)(!)%&"+"$!"(*"("'#)!*+##""#!$'("%('+*!%*#%(%$+%*"!&'')'"$)!)'%)('**#"%&#)*"'")#)#&'**++)#'%&+++!*&!')!"#&
@r6870
CACGCAGACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCACCCGTTCCGTGCTGTCCATGATGACAGAAATTCTGCTTAAGCAGGCAATGGTGGGNATTGTCGGGAGTATCGGCAGCGCC
+
7,8'2>5FB'=8'1.'&D)8,G7GF45:5-,=3(707)6#?@$9:FA0C1-EF?"2=$(D:G+03*,(,;4."%,A/,E*%.BF?-.-"H7@,(!2#+<,#;H,;!,-47=/5-D-3GF$H'F-G&EGH="8A#.#7C4CC'=)'234+$*024!3E
@r6871
CTCAGGTTGCCATTTTTAAAGAAGTATTCGATCAAGTGCGA
+
7.A!>@C-+2-'3&2&1"=#:89$4<D*H=5/F4C!<4B)D
@r6872
GCGTCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTC
+
=6.7EE&:AHFF/9A!2&),9<3E*->CD%3E!57AH6A)(0C$->-EH$40%/3#+*-32DDF$;+C#-;!F688/&4*,&1.DF-6#*@=06#B$#
@r6873
TCCGGCCATGGCGTACGCAATGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCNTCACGCTCACATAACGTCCACGCAGGCTCTCATGGTGAAACGTATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCA
+
,>$G"7!7&:D"+@5$<+$?0#.D0<>(+GB'FA$3G(D4$G48.,0'@:8*:,7?(F"C0$03D'>$"C7B4?6'&1AD7C";,B53@'4,B>@3*G%3A$05E@1!!BA4?D=GA2C8G0D3=DA6->4'%.B./"H(-84&,<,#4$%<EG7.$9::-:B3;+?)*5"B<?4):8'7:=8(
@r6874
TATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCNGTGATTTCTCTGCCTTCGCGAGTTTNGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACG
+
&+("('#($')*)*&!'%'*#($%(%#))%#!*#&&)&"($()&&!#)(++*($++#%)*$!++**%"%)&)##**%(!"#++%'*'(($%%)$))++!!%(")+'$
@r6875
CTNGCGATCCGCGACAGCACGAAAGTNCAGAATGCGGTTTCCACCA
+
(%$+#&"!"++()*!)*(($%(+*&%(%#%$"(!&!$!#+!###'$
@r6876
TTCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCT
+
#B*H=F&'%2=.$)/3=+55+-E:-HB<GA8/6,-7):2;D3&%@;7GE$123F,#:+@.;(D'HAB8-,D9:)171=B:*1F4&:E?9H=46:6-
@r6877
NTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCC
+
!/*736E)$#B%*'/FF+/*<!))"7%:2,@B(75?7F-03BHAB
@r6878
TGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTANATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTG
+
<#4G:HB/07B":/7:/D@4<6.."F#(#D@A-B"D:!'.(2DE8863)5:F510FEF*+?9D+:)4*%+!6,:8@0C.A9&?<&AH3E#=;7C8H@+A>"&F#8+
@r6879
CCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAANGGTGGCAGAAAATTCTGCCAGGGCGGCAAAAACGTCCGAGACGA
+
+:$A2F=667C#H*2%*"8;B*'3-"F;.>9GFG.!)%9+*B1A4H4:G(7.1:(25H,1"-#E&@%FH@>7H<@+<F8=3F7*85D442"8283*03.-)5%DBH1H>1E*6+G+.
@r6880
CGGTGTGAGTCATCTGAAAGGGATTAANGTGAAGTACCGTTATGAGCTGACGGACAGTGTGGAGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGC
+
F411080D?F/7F+@,?D%E"=*EGG);0!>?,G::4;F+9'':275)6:G@$,6%H7?&"BB22(15.$(>!/CE@69C'":%,A&+"9==F57
@r6881
NNNCNNGNNGNTTNTNNCACCANNNAGCCGNGNATTNCTTCACACACGTACGNNNNGACNCNTANT
+
"!!""$$!"##!!!"!#!#$##""!$##$"!$!!$$!###!$$$"!$#"##""#!#"!#"$"""""
@r6882
ATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTGCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCA
+
1<8)A3+"<G-<,$('A'<6A5H5)(,;?C&45#?H=963%<'G!G/./F%H;6G?%-G*>)(9,GDF36,;A=#=<@5):5@E4?D5;E1:+?-)F9043".A7@F+2H:"A@"D+0??%D;"8#:F!#78!+A7+@;.#%
@r6883
GCTCGGNAGGTATGATGCAGATAAATGTTAGAAATAATTTCATTACTCACTTCCCCACTTTTTTGCANAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCA
+
+'!*&%!*+#&')&#$**&$)#!#&$%(#"+&&%)%++*'+*%"+(#&#+""&+"('$$'$$'#"#$$"#('"!"(""!##!##'#&'%*%")))(+*%!%$+'##
@r6884
CGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTA
+
38'B$9/<1C4H@.%-#D2?G;>=:<C*C!!@3=:#&<6,/@'/.7G+",:!3*0#E3-CF)8',%!BEH7A39&A&2+3;
@r6885
GCATCAGTTCACCACCTGTTCAAACTCTGCGCTGAACTCAACACGCAGCATACTGACCCGCGACGACCATTTTGCGCAGGTCACCTTTATCTGCCGCCACTNATAAGGCGGCGTCCACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTATCTTACAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGTCTTCATCGTCCACCTCCGGAGAACAGGCCA
+
A/8)DB'2&3&H(%6%4*C;5B&:,)>0-)H0?AG/63+*<-#7A<C11>>289A4&/B)4'(E3-E*5>)9G.82(38G"B:7-F7FG'>2,6+9/2;=.7+'?%@?+)A"&+/';H;"GG<747F(*.+%0+"FG=:;9C)F7EFB?.A?1+@;#/1$)!-5.*67@4,<>64E,)D#G:6;5/,0CCB<4.H.@.*&7--A1'-E?-B.%<HC.=(HB<:!B--1.%9@97?$>!?.9"E'6(>@:,=DH/2+2G<35B'.58/"(*%7G227&?=*?7/8;1@"D1!1/#>17?32,-69!G190=(+A6CH?E@!-B?;@.&9;'!E1(=8G?5/1+*.224E*F%75
@r6886
GAATTATTTTATTTTCTATTGTATCATGCTAAATGACAATTTGCTTATG
+
,%GD790(:/+H5E4*#HC0DAB:*)6+G4C><*;@9GBEH)?@2))H*
@r6887
GAGTNCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATANCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGAAATGCTCGTT
+
)#)(!+'*)''&+(*%*#+'*&+)*"#%%$!)+)!"(+"&($*(#(')$&'(%*!'"$%&#'$#*'&!#('((*##)&")!$'#)*)$)#*%*+!"&%&%''$&!*!*#)
@r6888
CTACTGGTATTGGCANAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACA
+
/=G-/6#/+(2+B!$%B(;$1%#<-<5"!6:1"3)4B'5$H!AD*E.D9>3;(A23=3(4.!41$>'A$0%?D*1722#;+)02-"-@4=*GH5>6*
@r6889
ATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAACATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGN
+
8;G16:8-D;C@,0DCB#:0?2/CDD@D,)G!$'&14?C39A9?-C!@3G(BD80611(?F1C<293*:5?&2@@?/A%)(C@'9A=('#>'6B/>.$)H1>&*(2,!,:'A966#G/HB2=C+?+6>F5F'-6+E<1F$2E):ED:.86GA'DF7%9/D53-6@>=$5&CBD92H=2)18C+D=5!$6A2$
@r6890
CAGCACGTCNGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCG
+
67@5)56"<>'F>$CA8"=:9"39?.;&,?02>F9/'+$&54D!(+&86%F3)?0=&0#73:/@F+(,8B#%-$2?5?G+#=<A$-:>7"*1$8G!$8&2!63'=2417"@9-D"F7>%<.07>0F3!CH+4(=6>CC3HG045!?!(
@r6891
ACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCG
+
3;FE?,"C/!=)6%$<7H/+19"*+")$</.<=#7#BC5+&?.:+D%B+%F8(6H-0,/1H:1=$8B.96<:@92;?8%,3>G)(E842('A($':=*>)7,13?16(*"H9!/77>B&/'#?<CF5!,>?B=GF:;744%!H+0*48EB+:1@/H&:+3HHC<<52*@A:<.H5:;<''),-*!361H=1@.)#)858'F"716FD*B,>F&(C=7+F/1F>(65:>"7<0;.;<=*$/D<888(")1E-&8H95A#>
@r6892
CACTACTATGTTAATCTCAGCAAATTAAGCGATGGTTTTAAACATA
+
$*;<-77#"A/9/,';46>%H<!;+#A;;G8+3.:)F5#B0B55,*
@r6893
NCTGTTGATTCTCGCTGTCAGCGGCTTGTGTTTGTGTCCTGANAATAACTCAA
+
!4+$7)?DG;.=B8,346%=8@E';/*@1?)1B7C-9G60=FDC(.!$H+F&&
@r6894
CTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGNCCGGGCATC
+
:'F0!);3=AA;3'**5*0%A2306,%F8C3"60FH.&"""<4&=.
@r6895
NGCGGCTTCCTTTCCATTAAAAAACTTTCGCAGTAAATCCCNTGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGG
+
"$;4*/?..85-D29+F';*BD%-B!28$B;#AH+DGC5'7G!)&,@FC78>B4/2<C64"0%/G+@:D<-G;:E9$(";+=0C@$C:!@D6EA988-G6#=4>!05/.9"$3CE/6GC=4F<2'/A>>&@
@r6896
ACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCNTGCAGGATTTTCCCGTCTTTCANTGCCTTGTTCAGTTCT
+
F='6,/;=&-$G@,#.F0(G:#9@9>-/#9AH0):E<8A)%""G37BG?:90&F'G=."(3'F5?-(E>)E&8'='++6E33((.)?2*!C<$4<%0=3&E3C'9=5=D<
@r6897
CAAGCAAANTNTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCG
+
"+%)"!#'+$(")#"+!"'((&"()")#"#"%+!)+!#!#+&")!)%$!($!'(+)+&)%+!&)"*
@r6898
GTCTTCTGCTGTCCCCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTNACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCTAGAATGACGNATAATCTTTTCTTTTTTCTTTTGTAATAGTGTC
+
.88E<AG%8$<*+B";E"&)784$&-669HA&:F.0,/#.+D,9B!%*=6-;AC&A>70#46=2%8")&>69,5,#?C$H#2'.33&61*9)#/F,+8.9F=.,4$.F;$4/@;<;B47(7+$H0(C(%G1B#%4922@
@r6899
ACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCNGTGAAC
+
9F?C+/F$3F+0/D67=@=EG2-#232276A+"$2%7C,'5?0@
@r6900
GCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGNGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGTAGATGATAATCATTATCACTTTACGG
+
(+*:C'FE.5.!@F'D&'67&2D2*F5#-B9C-G$1EAFB"=9B2&B7.GF9D8;-4&?HBH94."%&"-4"'/"?>&#F@)$61,?F!::@.0215C%E/31=3%5;AE-;<3.FGC1$AB21':A9F53!8!#FBC<$#D2BE"AE
@r6901
NNCANGAGNCGCANANGCCGTCCATGAATGAAGCCGTTAAACAGATTGAGCAGGAAGTGC
+
!'!&"!(('#%)*!)$+&!%#"'+')*&##*")$'+&%+#%&"!)$#!&'#*$$%*!)*+
@r6902
CCCTNCTNTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGNCCCTGCCCGGTCGNAGTCCAGTCTGCATCTTCCTCATCGNGATAGCTGTCGTCATA
+
*'())**$'+'"#*"$!($"()$#!%+&+'$(*$*)'))#*""#%#(!#$"%$'#+*'&(#$+*++)!*+"'("+$"%+#+*)!"(!*$#++$((#*))&%(+**+#$!$%&*
@r6903
GAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTAC
+
&(FH6144)8G;,5,B!G5&8$,4*<;;#FB6.,.F<7+06.
@r6904
GCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGCCNTTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCACCCGGCGTCCATTTGAGGCCCAACGGCGTCTCTTTGTCGCCAAATTTAAGATACTGC
+
)7('?9+*)34".,!3.%(G4'&!?,$D3!F2>C@@*;-F8?;D85&H2/%6G9/&@?/B-*8#6'+&63&5702-)CB,AFG/6,76!*6<.A5-F$1)B&$3"FC2FG/9>9.),9'9A67F2.967E0./)<
@r6905
NNNGATCTNNNGNTGNANNNCNTNNTTNNTNNANNNTNANNNANN
+
$""""#"#"#"#"$$!"#"!!""###"$!""!$"#!""!!"""##
@r6906
CGAATCACGCCGCAATTTANTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTACACCGACAAATA
+
$16-$H3>-H##AF,DB9'52F;:C820/7?>#*B#'@>="B4F"&(5D,1"0<*>G1>(%<;'6%*3B"G0-/.-;&"*%!2EB+,22EC
@r6907
GAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTNGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATC
+
:A<2;&D.17)7633D#:3$!:E,!+%:7G%<02+5CD*8>6;1E0"F+D,.:)()8%"5<,6#.C"+F7D)9;;-G$(>=&%/72>B);D1:<>C6BB>)2G!!C+A
@r6908
CATCTTATAGNAACGTCCTATGATAGGTTGAAATCAAGNGAAATCACTTTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTNGATAATTCATTACTNAGAGCATGCAGAACACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGT
+
6F92'@8@>26H$-?6=)(3.,-%=BBF>F.(5)FB:5>B32$0>")",,"+"&E2D#)4FDE04?0:343)G)8BH$D22?G-H*$*23$92!$@>&>E91CA3C1=<.3?;673>22-<;H.&&DB5@C8F5="!41%(;E+/72H;B1H#2DHH)55/408!B9=1!C8#;!@5*#!?52BH7>5!%:@57?.%H)H@@=G-0&)1('E!=>A/::3;?%1F8$0G,966)DC,3/';=";9H#7%%-:6A)13&,2<9E6ECH
@r6909
NTTATGGTTTGATTCGNTTTCGTCTACTNCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGGTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGNCTTGTTGGGCTT
+
"?#D&,%>&G%$:B;=F?BDED9:6#0<6(18(3-$'-B%*2<-G'67<).B<!'4C>(<?G(/E>'#(#F44+(E3,%"C81"-#)=)<E06&B.F%2;31#"(1-;H9?<E5>.$!>3G"5@2"&<*&#$,4D//A-3?$5!8$%+1@"9@/>D/AD1-C%F%-3;D70-*"F$!7(-$&&>E)(9>GC2;F5H1(,?*?A-/6?/F%E41%70H6C$049&5$&/!&);.A;,@11!=#</,8?G2GF6@&<:9*:@"<3"B7&&5
@r6910
ATATAATGNCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCA
+
#+4>%>/726=3A!8B(BC5+(8+/"509;39250@58798#&@1=>5*>+*G
@r6911
GGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTACAGAAGGGACC
+
6?,//D$5395EG*3'/*/&@4-BA;H3=+H!GG071-C)3:'E)$#8B04,)/F%F;E&CBA+C;0#<B15=D
@r6912
TGGAGGGCAGTTGCGGTCGTGGAACCCACCGAATGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGNATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGG
+
ECA7C%,)</9.'+.E1(=<):85F/&+.HAE$9*??3(14:;@H"D3.*67'G)+@@,.D@)D&.%94?!<*0./8+<),$&</3%4#FB+/ED4@!9;@21*'!,-6.<*@1(8:B73C=!:CG&4<,#!@<#B!-90-1)63+'(H(<4#4C:?3F'8@+38)>1G>0F!AHD?9+E$)=<DG:$,!
@r6913
TCAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGNGAAACGTATCCT
+
"!H!8':8*)/;7D?G:G3/&61#)04G2-@840"46E0&AD5,#09;!6AF$F00/75E/&<*
@r6914
ACACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGNTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATC
+
"7D/.9=?BF)=7F="?#62(&>B?F+$@*-3<7,(C=$E2@/=$A"*!:D6,=-(F0"1AB!+CF&@.;4"<&D%A(6(G",0?.?."
@r6915
TTNNNGNTACAAGTCGGGNNCTGANAAACTCGCAGGCAGAACG
+
&((!!)&%&"&'$$)**("$&("*#"!%*'"#+"*#(*#)*%)
@r6916
GTCNNAACGTCCGCCGGACAGGCTGCATCGTCAGCTCAGGAAGCGTCCTCCGGCGCAG
+
#"%!"&+'*'!&&'"'#$#'%'#+*'()"$"("+((+#'%$$#!*+"'"()(%!+$!)
@r6917
ACATCGCCCGGNTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCCTCCAGATTATCCNGATAGAGATNCNGGCCGTTACGCNACCAGTCATCCTCAC
+
*E@>&5;0!<;:;=!/8C!4DFD;;@@19A,(F%>2/<)G,!'F(#=>>DH4&'#A?E4,5D!4B6-7FG/#(6";-G')1129D/.?.2;23"!F$4)1;&E
@r6918
AANNATTGTTCGNTTGCCGCGAGAATGGCGGCCAACAGGTCATGTNTTTCTGGCA
+
$"%$"*('%*#&!*+#*++!%'*&*'$&!+!%!$%+#+"+&')"!##((*%+)("
@r6919
ATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGC
+
H?30H=7;*&ED(3.0#279-8%B6*H"=78<7&$'C$4-77-;!-H$#&>
@r6920
NNGTCGCCAGAGTGCCGCGATGAAACGGGTATNGGCGGTATATGGAGTTAAAA
+
!(+'+*(%#*+$"+'"+%!+)"'!'!"+*+&!"'!&%'*)(&$'*++%"$)$(
@r6921
CATCCTTCCCTGGTAGCAAACCGGTNATACACCGTTCGCCAGACCTTACCTTCGATAACCA
+
*!'"+!+$#++%"&("%$")()*(#%''%"$''(+)'!('!'$)'**'$%)+*'&()*&!"
@r6922
NGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCNTGAACGACCANGCGTCTTCGTTCATCTATCGGATCGCCANACTCACAACAANGAGTGGCAGATATAGCCTGGTNGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGNTGCTGAAACAATGATGTCT
+
+%(+!!""+"%+*&!#(%%!))$")!*&#+"#!'#$(+($&%#%'%)#($%+*+$$%#$""+*&#&!!$'%!*$+'"$'(!$#%#+%$"$)($%"*&%%'$($&+%!(+&&(!'*+*!!!!&*''(*(*'$'%!$**+&*'#(')*'*'!!%&)+"!&&&*!*'$)!*+##('"!%$+!(%&%+*&')'++!**!$)!+)()*%")%""('&(&+'$&"%'#+"*"*)(#)
@r6923
GTCTGCCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGNTGGCTTCACGCACTGACTGACAGACTGCTTTGATGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTATTTTGCATCGAGCGCAGCAACATCACGCTGACGCATCTGCATGTCAGTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCNTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTAGAACTGACCATAA
+
7-/2>5*C==8/<0:<&.4,D0HA:15+>CGE.>F8F2'=D>%8>,%;&2#7"9'/4:-BF).%7"4#<*?1,+@"'E=>A85GC+2B(4:12./4#F:8G%*F"+<63GH"8B,#?,11?/C#H7&G6;.9F/04%GFF(#>9)?#%7'>D=$#EF#,(!78(G!*+3"07%'!(,"HEC;.3BAHF<%2H>,9!+%<>$GEE#/F<GH#<D2#9<0A<C*,-9**"034E;%B%5?0:#)-$97B>&B-6<2+?/*.-A18D?$C6GF7$/.F+,!2FD#;D%-DAC;3)A?81B:#,B,6@-E2),C83;A@E"4?(2FF#'A3!C!3?0#3?A':!.:?.7?,-7=$0*':#$>:94<='"+CD4$?-F++<'@E0$*E%:-8<1<()%:*F:$>'(4)"3*$';<<-."$B>4&/872B+$7.265H=&6A)1G*<<1
@r6924
NTNAGNACATANNATAGNAAATGGATTGAATTATGAAGAAT
+
$%%%&#&"''#$!%#$)!'+&$)"'*+#++("!+(+$'+%+
@r6925
GCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATANATCAACTGCACCT
+
,4A6&B&:#$BB;*8,*7$@9H+#H40<E4329@&,<H49,G$:/483@27G%96:D>!=3+E'G!-"22FE1*H+9B+GG3"B
@r6926
NACTNNTTGGNNGGCNCNNNCNNNNCCTTGNNNNGTCGNGNTNNAGNNNGANNTGGNNGGCNNNTNNTNTNGGGTNNANGNANNNANNNGANAGNNNTNNTNNGNGNCACANGTTGANNANC
+
$"!####$##"#"#$!#"!"##$!!#!##$#$##""#"!!!"!!$!"$#"##!"##!!#$!!!##$#"#$$$#$!!!""!!##!!#"#$#"#!"#$##!#$"!$"!"##$#"$#""$"#!!"
@r6927
CGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTA
+
$#F:,8.D74>*$62(:A74EE?(-<)=4=61,BC.8.57C)<!>D)C.(',8'!='38>?1<)#,"H%"0#.B75H4
@r6928
ATGTCCCTGTGGCATAACCATCCGCAGAAGACGCAGATGCCGTCCNTGAA
+
D9;",F.6DD%-7#+2A%<:%,/8)$)0>@D.C9982E"DH/H.D04%9=
@r6929
NGNNTNGCNNTNAAANTNNGCTANCGNAGGCNNAATNANNAGNGNNGNAAGAACNATGANNNNGTNNNGCANCNNNAACNNGNCNNGNANCNCATNNNGNCANNGNNCNNNCGACNNNNGACANN
+
!!!$"#"#!#"$"##!#$!$!!#"##$#"!"!#$#"$""##"##"#$$##$$"$$!$#$!!$##"$!"##""$#$#$$!"!$"""$"$$##!$!##""!"#$$"##!#""$"$$$!"#""!#$"$
@r6930
CGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTATATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAA
+
*'B!F#<%%(#?=6=#A5AH(EE4=!?#>4+!#*<3$38:FC1B//*9)(67;H>*B##G(F!&,A74%?$*??#1%B*;5421$6#E@4?C=B>':#;06&
@r6931
ACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGGTTTNGCTCCATTAGCNAGAGCAAATATGCTGACGTCCTGCCACCGGAGAAACTAACGACATTTATNATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGA
+
#?=-@E*9C<9.A56)A9;/H?-@,?431"%1!2!@>-*67;.11H2!;#CG<A3A9C74%45E8F0EA)A06/8B3#BE'4H/');9,''(37.8024<FBE;&A49?*%>E!2=G;(-$G((20G3'+2=B6H/;+G+?3GG4<9CDA9.)*>==D82D,'%6&C*2H;&53#E"=:..*(@5?-!#+(
@r6932
GCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCANATTATAAATTTTTATGGTCCGTGGTTGTTCACTCATTCTGAATGCCATTATGCAAGCCTCACAATATAGTTAAATGCAATGTTTTTGACGG
+
H'1B!H,E&!.:)5=2-'/";$%>3!9C.))C)=C'=@=#0+G&H?%.>-B9%3&$%(:?2&!(14/.5?'F/'5"8+4$633B95BG6FD&8E;647439*%/5D'.A+C8D7*/+-1/%&6#.3E01@1&%@0%1:(7>+B.D<964("=+>E+(%
@r6933
NNCGTCTGACGCTGGCATTCGCATCAAAGGNGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGTGTCAGATGATG
+
"#")$*+'"(&&#&)*$!")&&*%)*(++#&)(%%&!(#$*!"+#+%)%*%"$""**'$*'$&!)"%""#%+*&#*")%&'$%#+$$!()'*'(***)%#*$%'%)+$)'!&'*!&&$+*#"&!#%
@r6934
AATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGC
+
#,87!?B&F)(C=7-C"27"#"D251E"<A9.$2152..0E9102;*!3/6B*&(A)2":'25;!%!F
@r6935
AGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCNGAACAGTTTTTCTGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGG
+
8>EA?3)17*HF*4-59)?GHD5D1("65H4C'*2$">AEC,#/D<<3F5H"-A&)B5*.5(6:-;%8(E%&8A.40@&#@C"?7D#)>G%2H5G.5A;/F)(.A<93+CGA'20B3=&*(;$H>G-2
@r6936
ACACCTTCTGCGCAAACATCTGGCGGCTTGCGTCCATCCG
+
?3A.>DB6:9H.*#)3!0H&#0B&%E&2-#52B+>)9F":
@r6937
TGNNAAGGNTGANTGCTGCTGCATTGACGTTNAGCGANAACGCAC
+
'&!$)&&#'*$%"&(*+(*($&$('%*+()$$!(++'$!"'%$!*
@r6938
TTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCAGGCTCTTCGTCAGCCTCGCGCCNGTTCAG
+
76/B;@G7*4B*>AF3!5E:2@)&#.>G!,),&)5>:4'GC%?=<!:C?:A28"A4'*<&7()127:B3(7:!.?@FF/(68@(("/F(<@F/&&42/A567
@r6939
ATCAAACGCTTCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAA
+
&++%'#'!%$"#*'!"**%$(&+$*%$$+'$"**!&#&&&(&#"))
@r6940
CAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTA
+
(/DB.7C1E%DD?,'-.*;%.3*)/?/FEF=1;7&'#>0%C8A
@r6941
NTCTGAAAGAGTTACCCCTCNAAGTAATGAGGTGTTAAGGACGCTTTCATTT
+
#:B8$4FEG.?!30B*%@$?9($51?F06>?C,4#=,)%.E*3=;)FC.=4/
@r6942
GGTAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTT
+
'F4;#*@F(3>+),91?:B40=+?$.0EF+GCAC27E2<0;2?=E%H0-+/)*:6D30!!+%8H->!!G4"-
@r6943
CGCGTAGCCCGTCGGCNGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGCCGGACTGCCAAACGGCAGNGAGCTGGTTGAT
+
:>$?#B?>>?5&.G$)90#6)07*#,"G$,H+G98A,8DA&G1*0F98E3/0-F=%G$4A3&<!>+>'%:'0F+4G?E7C36%5C:<=2>:4.344*(B;B3-??@-A3F,<#)C<)
@r6944
TTTGCAGTTTTCGCAGATTATGTCGGTGATACTTCGTCGCTGTCGCG
+
'+)$B@"&1-E2::8?43'F3!<;/A%<9(F?E=)*(.+$99G-)$!
@r6945
CGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGATCTCGATGATGGNTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATNCGG
+
3%D.G<)D1F#9C6H9+;6FE%-$=(2";E9;3$2.E+3)#<(2D+!8*E-49.EA8&,;+/G)9941;>=-->3<2%:*'&>#'%4A!<=@&=!%*B?7/78.(=,'/8#=EB@>$0!>!8/3=%45G.2:F=/$G$C31:2%::-?$4%395G&F+3H<,*4<7>0@6/3)04#.*94BA45(5E-0>@C>;,"9
@r6946
GGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATC
+
C//5,0922GF8(>('8$D"*FH?%/!+GF?%@?0G9GG9?+8<H50G%A8
@r6947
TCATGGATATTTGTAACNCATCGGAAAACTCCTGCTTTAGCAAGATTATCCCTGTATTGCTGAAATGTGATTTCTCTTGATTTCAANCTATCATAGGACGTTTCTATA
+
5=0--''608<5CB=,E7'DEDE1D;0>C3@!45H,8=+"9B*?ABHA#,ED67HA<50)655%8,82CG/$C=H5+<B+!:,,.:6.>A-52"A,+%6<B1%G&*8)
@r6948
TTAGCCAGTGCTCTTTCCGTTGTGCTGAATTAAGCGAATACCGGAAGCAGAN
+
1')0H1)0-@?D,1<A"+2&-9(>@!=.!F<9'7?!F95B-9<A5?ED@:1C
@r6949
CGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGANTACCAACAGAAA
+
2>DHD-D?='.F+&9C<H@?D5&;A67@)1-.%(@&+/C=HH3F.9>0;<?,+.F7.BE(G#.@F50G%,/B*
@r6950
GCCAAGCTGCTTGCGGTAGGCATCCCACAACNACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTNATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGNATATCGAGG
+
.@$$*<A)#+A=91'&9!@(F26.00G$!<A@#%5*7+B".DCGF:727BA2)-8G0C4EH0C$(:E2A&1;#))F%C<:AD4(?$CG)9!/?./,G;DA"745!%%"8+G&*D<"C)<6C;D!").#&1)2);#7%@$>51H0@)5*$/>=79<#-#4"&1B#//6C#;8A/"->9!5)0.GC."27&3C;EE!<;)@.//&*B?9;"?+&7G5F=$5
@r6951
ATAATGCCAGCGTCGNGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAGCCCGCGC
+
D+8CD'%%?;C;F@F+GEC1449##F(6.-1#GG6#1%:3(7AC/08($+>?#$1:+B7E8C%)+8@&$;B=$#94"1&@C*C3B%+8;932#@GH@H#B@3.(0)<6-;2G
@r6952
ACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCNGATGCAGGGGGCACCGGCACCGCTGGCTGCAGGTAACCCGGCATCTGATGCCGTTAACGATTTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCAT
+
1.2/'=&>/7?#2C;=<9#"7!)!:+,:'7H@:7-G+5$(;:7&B3E8";:52?9<*25:0$,F+&D<A1-0,HAE:5=,?E=:?,H%;2'<%H"=>5;0&'-:6>BG?(9*1-@7*2$4"?'&,"("#A!E/0?9=C=GE*":8-G38@;?FD9('.E,3FB18$G:)F"1*9#&#?1=%4*5;?"?1)(BGB?AH4(%":A1(.&C=$:'?CH)1G>0@3>1C2BC@H)!@;,2&B&@?
@r6953
ACAGTTACCCCTCTAAGTAATGAGGTGTTAAGGACGCTTTCATTTNCAATGTCGGCTAATCGATTTGGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAAGCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGA
+
*+$+(*+'!%!$)&&!"(('###"$"*'#&''!"$%*#'''((&)$*''+$*("&&%%+%)")!+"!)*%&)%!+'$"$$'$(!!+%($#'+(*"(!('%((&$&'"#''!"$$!*)"*$#%$"+"'%"$%(")"!)&*%#)("$&")&%'&(*$)$%!*)($)#!()()(&('%%(*"*))%%
@r6954
GAAGGGNGGNANNGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATA
+
#()($'!)&!*&&+%*!!(&*+%%$%*%$%'%!!*(*'%)++#&&!&$+$"$$*!'"%&'"#((+&$(!#*!#'!&+%)#++*+#(*)%&""&*
@r6955
TGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGNCCACTGGATGATATG
+
H8-H$,2:D!>"=)9?5%A<.)?D;/./7"&51/&H#<#5&!=0'+:<0:@4%E/#2DG/<<!B3C/7;
@r6956
TATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACNGTCAGAAAATNCGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGNCGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAG
+
"53-:"9C46&;+>'6)C:6BH2?EH+,4#;&*FD81#3'6<A5=H1A.-*5+A;7%67/3,@#8%&B1):8?)8*<?@2B".:5.'!*GB;D74>B"#+,!;!2$&3B<-"G%FG*D)%H4"9$!/G(()AG
@r6957
TATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGAATTCTCTGGTTTTCGTCATCCGGTGGAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCATCCTGAGA
+
/D>BGB/!@D/G.<5)(B."-:12"=@;",1,&3#GFFA-;8+#9;0A81(*227B4=@?G@G?+)E2)F?"80.),5"H7;-2,&1.,);G@9;6)+</,G;>%31'9&5-1.5799G89*F*-&:2(@9=99$+"68G>+=H%/)/'=053!"F3D72DD:B/,G;7
@r6958
NTGCCATTGCCCGCGCCGATGAAACGATACGCGGGTACATGGGAACGTCAGCCACCATTACATCCNGTGAGCAGTCAGGTGCGGTGATACGTGGTGTTTTTGATGACCCTGAAAATA
+
"+*+&)%%(%$(&&+&$$%*'$"'*)*$$*%&(+()&#!!(*%'&(%"#*'&&)*)!!'*)&)(&!%"$!!(+)+!*"!#%!('!(%""+(+!(%*&"%%&)('"*$"*+"%&'!(#
@r6959
TTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGACCGTGAGGCAAA
+
4-,.<4C#6A*F8@8D'6@1G.";!D'0D/F34F.1")-H172'</"'CGH)G>E?@,E+<@%=9(G(7/!HB-6D%B/D;2;F':41"?H#BCG:+3>?F283
@r6960
NACCATTAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACTTNGCTTATCCCAGGAATCTGTCGCAGACAAGATGTGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCAACAATGCATTAAATGCTTATAACGCCGCATNGCTTGC
+
)(?#&#,;A662>0+(&?6A",*<":#1?#B=A@EAB*>-#.-45%B"/%<H?";4@3D+80@!#@6#7,H"D?9D>A?'H)C0<01D#<"A+%CF7GH>5,3;<#E*E?>0)30*CA#<+4CH"".,B*H&.BCC'AC<@&"4424-CD60(H-;&4.%*?97/14@=%G7))C?:$+(@0?@
@r6961
GCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGNGNCGTGAA
+
$"B/!9/D,A*48+;0,:9(H,+A'*D%F"+=1(",=-G%8<:A;.?;:2F02;0%$<.?G);A
@r6962
TGGCGCTGGCAATAGCTGATAATCGATGCACTTTAATTGCTA
+
+#%%#!$($&(')"&'(+#)''!))+()'&#*(&)'+"&*+$
@r6963
NNTNNTGANATTGNNAGNNNTTNNCGNANNNNTGNTCNNAAGNANACCNNCNNTANNGTANNATNNNANGGNANAGNTGGNGNCCANCNNATNTCCTNGTNGCGNGNTNANCAGGGNTTNTGNAAC
+
!"$"##$$"$$$$!$"$#"!#!"!###$!#$!#!#!##"###"$!!!"#"!$"##"$#!$"!!#!$$$$"!!"!#$##$$!$!"#"##!!"$##!"$"$!$"$!"!"$!$!"!#!"!$##$$#"##
@r6964
TACNANANCANCNGAGCAAACGAGAGAGGTACACCGGCAAATGGCAGCGACGCA
+
'!*#!"&%")''"+)+*"%$#%!!#%)+$!%%&##+$(#+"+"(!()''$(")!
@r6965
TCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCANGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGACATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAAATTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCT
+
.+>:3CA8<,9-$-298>92,-.4=F/1*;D/8G0D;66/?''C-?FA+8&"5?85>>-(C&=BG?(?5B;<+#@4>-8><B3CDH2F,07="??%D,>&60.-8-:@C+1F0*%-@A.<$>H#+1451F;="B/:9>2%+:;'5;*B>$81/!@F00.!>(<&)9=4;)6#B$%*97%0#;$"*$?(:5#8;$$70#%<*',(3:?$493!E%$E#6*B29<(42<@#CE$.F&51><C242D+B!+?-F1$+<'5C)AG!!)9,E:EG16!5$*/&&C',6<#=,G(;@GF%+0.;"4>$4+";;"!?)"-1F@*'D5F>.1B*?=D>C;$#32B501/(&)@70<G0,E4D>1.D8H-5D3G#&0*0"A833+H+0$D6
@r6966
AAACAACTGGAAGGGTAACCTGTCGGATCCCCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATNAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCATCCTCATGNCAACGAAGANCAGAACCCGCAGAACAACAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACANCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCTCAGCCTGGGTCAATGAAGCCTGCCGTCGGAGACTAACGTCAGAAAAGAGAGCATATACATCAATTAAA
+
6#,/H/3,==/BB7($ECH>D3F<#(.(<#.'<*)(?$#9&HF3(#=532"3*!"H:E2?>:/7?,$3+.G7*BD<</4&0!C9(G;"'$)'21:;'=<=>H"3H".4C7EE@0-/99).&8D11@C*E.=<59,8!.#@%C:5AB8B=#?>;#@)G:B73@4/D88E!3?@C."#15GF<E7'92G#(<B7'G:5?%6G&,G#$G#4D")HF9:D!<C16&323@.3122:%-H!CCDB67)@)!C=-+,9>DC6=;6?(%%#.$5%'B%A(A-@.*$E#:(@,(3G@3:E2:H38(-;4%C1:G&9H'E"+<G,"FH(/#'@%E#&BG7-*-*A)*99B"/*)'104*'0F4F3BH#09D.>5A@*#/FFG=+C#A*4%B1$69+:4H78
@r6967
ATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGNCATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAG
+
6F;&/%G*G"+B2#79'2;3.#-B7&-1C97$+,(:C00!>'3:@-5:)<B/@F+%2<2B331349,D=68A&@/&E21#E/C-(6+&9DA@>=&G>*#H#'B>,16F.D328<
@r6968
NNANAAACTNACCACGGTGAACAATCCNCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCNCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGACTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCC
+
#!,!5DH),5(7#"),B?5/#0HF6.D+&E,6)<1!3"6E37!01;6&!4.H=A44C;!<@)0<3E1."9:!.>D:9&DD>+AD#B.#C*D-8#F)F&&,:,;E79#E:"!;,C$C*BA!5,8!A=EB7>03@D#68&/:D3F;A!>=DD!.?A6>&><A?'&!C1-(,*52E',)@FG+C2C@<):5:6A(H96,BC2$.-'>G2#8(="462F#0E8!1%(527,H6:B3'095;EA.36,
@r6969
GCGCCGGGATTTACCCCCTAACCTTTATATAAGAAACAATGGATATTACTGCTACAGGGACCCAAGGACGGGTAAAGAGTTTGGATTAGGCAGAGACAGGCGAATCGCAATCACTGAA
+
H(6:1C0<-=D<;;8#/9@B=31>,#,'"/)$',1&0)</,C+4#4'&%)F3:#G3;&D-#'!#&97E>";6!%07@,&D'D=CE3""C1+/82A7>"%G=B;97;H97'94=)-!1$
@r6970
ACGCCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCGGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGNCATATTCACCCNACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCAC
+
*?"3D!:C1>H<.'BF9G5&B,4$!H+/B>?*&.)3.;5'/2==?%9C75C*$1":$E?.7(CA?!13>!0#3072-3C>:@#;EA0;@<7,?B5=FH<GA&'*0#0803H3<@;/-AFA&,=H(=:&.59(.!(E=1H!%8D)G'-,B(3#!F2H4C.;HD+3+!43,96=H@%%5)H/=H54-%F#41+"=(4<("D5$84>4364+265+%9<+8!A69"HFH-$5?#C+@:>C8=)-2D/.*&6<C'%2*0(473!A
@r6971
CCAGTAANCNCNAGCCNNNCNNNNTCNNNTNNTGTCNAANNTACCCCANANTNGNNNNNNTNAGNANNNNGTNGGNNANNGA
+
$##!"!#"$!###$"!!$#$"$$"!!!!"!#!"#!#!$$$!!$#$#""""!!##!#""!#"$##!$!""$#!!$!!##!#!!
@r6972
TATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGCGACCTCCTGCCACCCGCTTTCACGAAGGTCATGTGTAAAAGGCCGCAGCGTAACTATTACTAATGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGNACGCATTTGGTGATC
+
=!3H/4AG!@+1'9-!F"-8->&8<5$.-6B+=#8,+9<'F)?2F&D+C+68';*?4$(5-+#,$@EG2%C.30E;/64+.399@:,5<A2G!!&.7FH*0.H"HEG#.5&1=7=9/0#$9/>?(%4B4#)=<CBE9B$<-9+(62)!3-H!=?DF7<A;HC58$2%%A@046H@>-7.-0=6
@r6973
NGATTCCNGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAG
+
"<(%*$.:DH)6'/C%&$4(85;E8#3$1-B/1"C@3->C/.9,(A!&6+8G9A.!*;77A;FA8%7EEF
@r6974
ACCGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCA
+
'&('*)+)%+#%%*$'&!#"#*&$"'%%("!$(%#++*()
@r6975
NGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAACGTCATGCGGCCTCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGNTGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGA
+
'=!3&=#,=5?H@A2#E1?-7;(4G0%%8F3=)07B///9/D67#$GDG+AH):*;A)C0D+B-15$D,4=6E<3';9:D99A4B+,2C542EHH'4/D(.F)!;'260HFF!9#59)3'CA'63+9%-("&07:*%#?>F$"CBG>5F0&:C906"=>B07*'=G+1>/H.F,$7G3))1;'4!:=0%?%4'GHF=B:#!.-:A?'42:,+90-@==C-!;H37
@r6976
CATGAGGAATACCGANTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAAGCAGAAGTCCAACC
+
C.C3+4@2H%"2C(B61G1'G01$8/H1G1!1AH8$H.GF//;AB)C''A%9,>2'=9:C6A);:A93F#?
@r6977
GTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAAAAGCTGATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGANTCTTTCATTAACATATTCAGGCCAGTTATCTGGNCTTAAAAGCAGAAGTCCAACCCAGATAACGNTCATATACATGGTTCT
+
6A?25E.27FGF;A<+29+4.5*A+$D6):#A"-7CA<A8">@C*<//&.(,A@+H4G2(>!?F-#8*#9H5F;D":<<2:G7G)+=);;8=&04=4);)/5%.56?2B&G#0$1#EAF"F6AA!!!8A@'2DD+9D+-!$/)>;278#;6<>%F4$"B#-;E=FA452B$#4!;,29%EC&:G(2,)#*C':1$A-=>!G,@45#.+!A"+A1C?=3/
@r6978
TGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCGGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCNTCCGTCAGGCTGCTGTTCCCAAGCTGGCCTGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGTTCAAGCATCAGCGGCTCATT
+
&5E/1F?&?</+?0AH"<*&G4B'13/?"@9@C@F362))C8!!54*.G$<H:':3=$:E#5(3)?2C=9E?1@!7%H;"C@;/F:;8!"@<*,4)8@3*H+<"F%8>G>3.,#%?9:9@?!>-F!0/)$/@#";E%F/&3<0D%6!F6/"*E0/H!802%)@)5G""@E;448H0,7C+43$:/<<#5(;42CF%24&+D;HD'&7+D"%6$B&FGH&#(>H127GC<
@r6979
AATCCCTGAACTGTTGGTTAATACGCTTGNGGGTGAATGCGAATAAT
+
3$555/*8("8!7*3>A!158G+C%D8*'.&/070B3G'H)&!(8<C
@r6980
ACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCANCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCANCATTTGAATCCGGGCTGCGAC
+
B'>==3-*$;*,)F%-4(DG<<D1D-FF8))H89#-9A58+,A#E=H2D!8=//@7/AG73F51*H?3>BC@F%'6;6A=$F"*:.)4%:?=)%%=9#!#<A!51;F@E/6F10,;H3#!/3>.).#*;0A1(?(F?=&5A%/"-$4)#
@r6981
NCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGTATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACG
+
(>7A#38D"<1F>*2F$>"9C")C%(/(**D)9&56?A58FDCG76?=&%HCA):)=D=&7>@;!+;E1<!15F0F=4A:8@'2135,H"883E8=;=;(!6;:/'+235"
@r6982
ATCTANTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGNGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGNTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAATGCCGATGTCGA
+
./H+/#"'5'B.:..-FB9F)05@1F&'!2E6##A+;.G?!461&)<">/'C4FG?!.4:CD6#E@"(G5CE3!*&C+7(&2/F'"??(6?4CE/C4B%-7C%EB9'+@:1)':%5G.7:',1(=9F,=73=1AH<H'.:E@1$!?9%/B5#A@#-B'H68?H#=B28.6
@r6983
TCGGTCCTGCACGAACGTCAGCGTCTGCACGTTCCATACCNGCATACAGCGCATC
+
0(2(/1C53&FC63$&9>>'.E*G9?4?<-57"=0E5>13$%7G>!@,:/5@C)!
@r6984
GCGCTGAANAAGCCGAAACAGTCCAGCGTGAAGGTGTCTGCGGGCGATCTTCAGGA
+
$7/=!:CF(;7:EC0A2-':*#?0)$?,&+2%>G)($25-7)C%$9F=:0.A/A./
@r6985
AGTTCNGNNTNCACNNNNNGNGATAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAAT
+
**!*)'*!&(!()("!!$&%+)()+*%"+")*+%%%%*$!""((#($'$")%%*#()*&)($#(*%#(#&!&&!$"%'%"*"(+&&$#+)'($""#*'#&(%$'*+$*)'!+$!!%"&#%#&"#"'$$!+$!*+%*'#!!%&&*)&&)'#(#''$%(#%!""+!*+%""!"+(!&%)((!)+)"$"'(*!#'!%'("++")!*#!"&%)+%!##$*%'"&(*(*#)%(')*)!'$(%#))%'"&#&*"*
@r6986
CCNAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCCTTCATAAGCAATATCAACAACGACGGACGCTGCCGGATTAATCTGTATACCTGCACTCCACGCCACTGAGGTATGCCGCATTGCACTTTCGTCCCTGGCAG
+
*("G*1B"7A-)56E.;A9E67.BG)4+=D0D"CD5:0/H-.1%!9(.1*,&2C9.E-C85)E"A01:(<5#,DD#&+07$3<.-!6@6D"#H4>9F8+>,5GD>-E9=):#B+66-#(+=E6+3C25B1D.9=?2.+FA>$A.7=
@r6987
ACNCNTGGATGTTGTAATTGCATGTATAGAACATANGNTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGNAGCACGATAATAATATGAAG
+
&!'#(+(!%"%($%)!%'&*&($())**(&&!)!!!''#(&(!'(#(&!(()#$"*#""+"*%(#'#%!!+('+$)$$#*))(!#*!'()&*(*&)&(''
@r6988
AACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGA
+
>19!E87%1?C"":G=,(7.55#0*)D9,B%*DF@+@/FD:
@r6989
GGNGGTNCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCG
+
&%$A,01DGB+-<2E2@%>)8H0!D7CAB%8A,5!$G&<8<+(7'F:B/8/$B952,!/1*0G:1./>H>'1.)</*+4H@%-8$<2-5
@r6990
CCGTTAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGTAATAGAGGGTAACTTAAAAGAGAGATCCTGTNTTGCCGCCAAATAAATTGCGGTTATTTTAATAA
+
(D1F#F=A:<6+<'-2)),?=C+>",,!E5-/.G1&EEE0-A%>"'"-!,*9F56H2;?BDA9(#&(G)=1#G0EH?A0:!5",48H'%25!D/58F3&+,>C24-."5
@r6991
NCNNAGCANTGTNNAANANACANANCGNANTGNTTTNGNNCNCNTCGTAANCGNNTNCNNNNATAAGNNNNANNCCNCNNNGNTNANAAAGCGTATTNGNNCNAANNT
+
"$!$###!!$#"""!#""!""$"##$#!"!"#"##!!$!"$"!#!$""#$!$$##"#$"#!!"!###"""#!"!$$!$"!$#!"$$!###""!#!"#"##!##$$!""
@r6992
NTANNATCANNNCAGNCGNNNCNNNNNANNNNGNNNTCNAANNNTANANTTNNTTGNNCCNNNNNNNGGNNCNCAAACTACNGNNCNGNNGNNANNANNCGNGANCNNNNCTNAANGNANCCAACANNNNAAN
+
"$##"#!$#$##$!""$$"##$$$$!""#!""$!"!#$#""!!$$"!"!$"#"!$##$"!!!$!"!"$#!!"#$$#"$#""!$!!#"!!""""##!#$$"#!#$!$""#"!#"$#$#"!!"$$#$$$####""
@r6993
GACACGGANGAAACCGGACGTTATGATTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTTAGTAATGA
+
(/9*;:G@CH*EB&!H:*5;C,D/.$;F)0#4(8/,!&,=0BFD8%93B:A;:?(3?7740*3-:HF;$7)<&#
@r6994
CCNCCATCAGTTCAAGACGACGCTGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCTACCTGCAGGATGACACTGT
+
?.90$A='C/*:!A#!B.+C4$@?)2>,)E!18H2%,&!6;9<?!8C*'.3?-#+B4"56-<+H,<=(=65.,>(FF@>,2D!7..%?HF0;G<$)?-&1+336.;H7#&CE5HDB@6G""(+#9;@.>!;'F#@4)A3(=E:#77H/F)5?B#)C7C-
@r6995
CCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCG
+
@<4:.#"++30'8;9/-,(!7)%C!'&?#6#73B(90&:'98#$12F-HDE1!&:0<$">-?
@r6996
AACGGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGAGGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCG
+
D8,CF:!4D&1E/'6+FC>>748'G7.87<,*321D%#219,#B@F3'*@/>5G("7:ADAB#C&E'7@;7@>)?1/D4!>3<!1/<,><2<&<"/!"399?0(''9749;7&<'E%=%*H$53BFG*
@r6997
NACATTGTNATCATATGCAGGANCCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTGGAGAGTATGGGTATATGACATCGGT
+
$'!+%#++$!"'&#*)&&#($'+$*'%'#((#(!'$+%()%"")"&!"*)&$(+(!(+%)#"+)+"('*!&&#&#"'%*#")%$#%#(##$$*'%!&'+%+!"$#$''*")+#$!!("*'
@r6998
TTGACTGATAGTGACCTGTTCGTTGCACCAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATT
+
+!#++!(*#!''&('&*+")$)$!*+)"&$%$%+%()!+$"'((%()((&$'+%*+#")")!$!++!&)%#!(&"%$(##!++%&(""%+(&!%"+%%+&%)#$+*!###($'+)("!($*$
@r6999
ATCTCCTATGAGCAACGTGNTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAA
+
@5:-"3?%'D?%4/G2#(B1'>%;=EB$77!A)B)D@(:*?/4AH)"+-%<$B2&:@967H?C290.9=;8(@?
@r7000
GTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGT
+
C*+C/2AA=FG*=1B/+5,*:=H3/F287&85&4/2)%CE%-E-,08:=?#0A9D.1';FC1FA559H7A63,6D2-#-$0G
@r7001
NCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGNCGGTGCTGGGTACGGAAGTGAAATATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTT
+
#9(,-H6AG";:6!/..--&$G8=;B;/+?:H585=4B3#2'&&H@$'$71(4>B8%&:+F)$+$F(E#,+&/D;E;>/&>,87F,/23FC4';-00"(40>?=;*(:/>H1?.4D8)BE),E-@E25++!D
@r7002
AAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGCAGGTATAGATATAGAGTCGGCATACAAATATTCCATGAANGNTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCC
+
,H9#9-1:==1=0-(C+C2BBG5H=)6,$9/4?G6:G3*G?0":*!4616=$--3A,F;07=DG0'(9B:%4C'#F=2(H%AC*$H81>&!%G';$5021=/,4!/A.54$$F*;#,:*11<5AD#2.7HG5#.>;"D=9<>7:BDF/EDF9))3:70+$*F;1C8,,507%2BA&.#A!;,3*..F2HC8!'E&C5=*,B4"'&C7.(F29BH0%&)>/.$7+2E
@r7003
ACTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCACCACATTCACC
+
"B5:E'0+%@C95,:A-9-?(&:H"F8*9*'9?..0<=12=-&G0H#.>D(;14@;A(:8(.%H:*49!#==0H6!B):"
@r7004
CAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCG
+
=?D&<(7C2CBB</,>&(F%C*GAB?H7,#7(<#3G00B,>.2C9.;,6!402(2F(B'1"F!,2#D@$>+2'B"/+)F)=C
@r7005
NCACGGAGCAATGTCGCTCGTAACTAAACAGGAGCCGACTTGTTCTGATTATTGGAAATCTTCTTT
+
"H#37C#<DA04F4#@G+B$GB%4)96-.9($&-D4?*?;B>&!H6=G*EB/92H'!B--782*H/
@r7006
ACAGATTTAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTA
+
HC$CD&?,07"@*7?HG-?F#>81-GH)'D=*5C<&C5%%A1&71+,":<<<?5!7BFB1B8,/D,2!4@@!#D&)(&$@?G5+0(*2EF2!@E+;!4?28/?E
@r7007
AGTTCGCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAGCTTTC
+
*1+1!;?9**&4@6E94>')8BD4HC<DG*:ACF.+!=1>2$3-&C:"-FD
@r7008
TAAGTTCAATACTACTAATTTTTAGATGGAAAACGTATGT
+
@4H('3C#F=8<FG+G.9<9-==4,@A186!F7F/H:)6,
@r7009
NCCATTTTNCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACTACAAGCACGCTGCCGCCACCTTT
+
".$=5>(<:/E+?13/F2B?3A'A+2*%..5:2,G$;.*6*3CG(F:>/B8'/8A)F+>=E(,@&5>!0!/F5>E
@r7010
NGGTATNNANGGCGAAAGTTNGTTAATGGAAAGGAAGCCGCCAAANTTGCCGACGT
+
!&&$'$#%$)#+*(%'(&#%%#!'**!&+)+#'*+++*!%(+&")"!&&&#'&&$"
@r7011
ATGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGATTNCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACC
+
3#1%G-H0%$+;,H;='=5($"8H"$7FF1?:@#4"FC3:)!",**2-$C(8FE:((04@*6541@8!"')$$'5D=+"$/1&0:'-3$6.?GG'>-97;:;
@r7012
GTTCATCGAACAGGNCNCNTTANTCNCTATCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGANTATCTGCATATGATGTCTGACGCGGG
+
&'"#*"#(""$!"$"(%)!")*)*'#)+'()%$#***$$!)(*&*#%)$&%"%%&""*&$%()*$!*(""'('*#+&')&!%%(!+)+*($%$"$'%!'##'+(*%+"$!("("$'"
@r7013
AGTTGTTGATTGAGTCTCTTTGGTCATTCGCCATCCTGAGAGACGGGATTTACGTGCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGNCAGTCCGGCATCAATGGCCTCCTGAC
+
G.678!C89#,'@10(D7BE?D!1G=.%$@&3,G&%.1,96"1)C)5'%<'G"/('.%+61'B0#;"FF3"(!;#6D9)8CHF,;%6,<31?%@<A:F#*+7>,=:@;GC>5#/(D,<G#A@98=-?"C5$C>!$B"%!E
@r7014
ACCTGTATCCATGAAAACGTAATGCACGTCTTTACCTGCCCGTCGCTTNTGCTCCATTAGCCAGAGCAAATATGCTGACGTCGTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGACC
+
#.C$:2:3E8C0'D-+:#-H?(80/C2)(5(2,6*F(4A>C??+75$HD476)3B?/9="-/$430'@7>2D;"F3E=",?HAFH+&B9-"63!BF()4;0!5;)!%#B>.6>FC4@7>H"$:$(1(C#!)?C0@$<8/.:G&<!,.C?=.8*$+.,F*<5C+5!:.(-$:'
@r7015
CGNTTCCCCGACCCGCTGGCATGTCAACAATACGGGAGAAC
+
G@D/,0$>(1@87F,5+H5#3.*H!FD8F*#>//47G!78!
@r7016
TGTCCGTCACGCACATGGGATCCCGTGAAGACCTCATTAAAAACACGCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAAT
+
7>9G9<*/2+0&>3#>599!<C>3C"++91-'+1&73(AEB-A!+5.+1C=2879'#6874D;+E@)*?01;>4E4(E#=5(%E&;+-GGB"FB$(!@A$D'*,-7%+/BC9D:@F,+?61+(,B4*0.FD$8#G16=(:<+:>;
@r7017
GTAATAAGCAGGGCCANCGCAGTAGCGAGTAGCATTTTTTTCGTGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATG
+
0=;#"A2(+%C4A7=6@88EF?6"5/*2>B9..A.80%GF..:16B(,HG7D931:2?9/B13A0?<AB6.BC8)3F328C-%.*<
@r7018
CCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCNTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTC
+
&%'(+$*+#$$+#)!%!%+$"')!'#!*+%#%#))!%!%')#'&%!')+!#(")((')+)'&'#%&(&+(++!)%)(!*$*&*(""#('&'!&**!%
@r7019
GAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGC
+
+-5G'H>A#@H!*D+<'$<-.61<8!=62:C$?'D=315D1/AA52>A?#+8A:-C
@r7020
TCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAA
+
E(?H66!+6</%>F->5%2?<14<:4%A)B?%EG=:60#:8
@r7021
CGNGGAGGACCGACCNTCGGATAAGACGTGGACCTATANCCGNAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGC
+
)(!%&+(!#&+'+!%&("!&$"+))!+&%"#*+$&$$(*)#&&)&!$"('*&"*'+('#%++"&*"%#%$+)#*'+#&&#&**('"!!
@r7022
GCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGGTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGC
+
<3%18$?)7/;;BB&#)7:-H>>+E5B'B=<%0G$5$210G75'<:35<6DG3'C59H1)-?(?E6H"(C:)08$15!(<C.B';AH+!40+;!:$-B-)/<H@=?<?-&%$9D&H%02#6,$H*E/59A2+D<%G44;+/*0/H10D*>)$7
@r7023
NTNANCCAANAGCATCAGCGGTGCTGACTGAATCATGGTGAACGCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTT
+
!)#&%"'&&#+!'#&#%$"!)!+$+%*%#'+!*#&"%'*'*)&"&"''&+$'$%)"!$*'$#!**)'%*$**!)+#'$
@r7024
TGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACCACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGCATTGG
+
'(=>F627F'!AE?99%=/12*776!-/H4B1=063FB'&F7#'G(&.('FCF;:>,:"A!@:.D?)G2-*%A:&$&&!B)19>*"!6376A'9!+6-AC"D@FF?)6(":8*@<6(5F+,6&6;#!)AB42;29&B;>'#B9
@r7025
AGGCCAGAATNAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGT
+
>!5-+<:D7:5>(%54-CH@D&&=E6>&1(?+%>-H<B1D,B'35:':$"4@1%->(D;C/<.HGF34+;&E$F'9"4>?2(1)E90>*3+*$2:7C6*6-'*)$"/,4=C"F'&0
@r7026
GCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTNTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATCACNCCGGTTAACGATGAAACCATGCANGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATT
+
?$*<D$"!/@B;36>=<:7B)A(G@5,E04=+11@2@F#1"AFF>8E1"H24-E:5)48.49&FC(D:F/%+>5#@C$2(<8>)>=G(E>!G-F=;/#AF((%'32/-(+!C#,3:,>H%(?,+B+</0%00!=030%C.2DE'>8:#05:7)"85"C43B4?617'3.00<'05/4$393&;@D
@r7027
GGCTCTATCTGAACGCGCTCTCCACTTCTTAATGACATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGG
+
#-:%@&1H3.396$7(5"12.E;6;66634=9$*3B1506#7:4&F,%D#AF:H?"C#C32+:'3A$>28,*:7HE8.*%180%8-"#B!D17D,950<&E?5--D(GF&$F358<G#239?:B!"784&."A*5,E*
@r7028
CCGTTTTTGTTTCGCTTACGTGGCATGCTNGCCACCGGCTTTCCGTAGACGGATGCCCCTTTAATGGGGATCAACCGGAACAGCCCATGTTTTTTCGAGCGTTCATACACAATGGTCGGGTC
+
5&BG6G<%2.,:FG<11C",5!&#'0G#35+!8-B!".5@8FG6%953@7;909@42"0$&9,6C!AE;1<86>.499..A,0+B".'.4#,F*A':B#97C16>8)-!*12'7+D68H('7
@r7029
GTCTTTTGTGTCCCCCTGTTCTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTA
+
-)%C=')*,:1AF)%*0=11/.'8$6F+EBCG>#5&8<G7D7CDG$FA3%&8>H"6E!(934CB:'F*!(@3,%8&?8$D%32*)=G=C@DF6.=)!$/';./37DC%0!53)=+,"+2G6H17,HAG7);*(+!93'?:4%.A'02"3/7(AA9(&%(;2:#E=G5%4+*8,
@r7030
ACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCT
+
)-)")'6?/CH8;+!)F#5E?-'4C70"7H</@;*!=-C"!C==?>+$9A!59HF3+"0)3/%,0
@r7031
TGCCGGGGGACGATTCATAAGTTCCGCTGTGTGCCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACTTTCATCGTGAGGATGACTGGTGNCGTAACG
+
034.">$@)G+'-7,'7:3GDEG1.;6;6!#24:".6C0/,+59%@5+9@.:2?+9.DG:=B"@(%(!BG)A3/;"GB,.B8>.=,*CD,6.>G!$$*H8*?*91(H;)4G'=7(#6"&*.@$2+84/4'07,G.=;(1A-<2C#G862#*34@A0*?-(
@r7032
TCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAANTCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGNATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCNGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAG
+
.(86!G/);(()8$'.,.6*6:F5G>#A%?;&@E1#,H!="+EGC#</A@+H3A+(G/=2+99<'D;HA-!D"@>&/;%-+=//1)9>'15@#'1"9($'3$FF11E='H);>+D5E-@D5F25%;"5#+,03F/'$=!D2,;!&E>-=3H+60.43"6C$@(71!'@07%G&$64++C*45(-7C)8=,57#50*H!E'.4%@:#-8(#(<+#FA(D-2!C15(>1BC"8<*FF81'&)#,!&-/C01)#"H@+'=D@#-4.H:>"=G66A#.,"(G*8H!8+)6#&1<(+G><(-(5D2?'=%/*:CA2&@#+.A;7'E3(@,<=';5;G<B-?16G'G-.=B3=D0,F;0G-.'38?'C%:"4.HH<2-5@A9>-F,-/@8(050%@'3.=611(@9F@)
@r7033
TTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAAAAGATAACGCTTGT
+
9'*B=+3$56A'!%5?>:$*B40+=<+(092$=,A7(C61G#0D8DF>)C,!G$F4!<<5HGH0#B5)"9(G0;6*$-@.*9&#E',)>?!,3GFA.=AHHE"E%/HH*CG$2CH<
@r7034
TCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGC
+
B2/C(1>."<E;>)0!H;$1/>GB?G3$!FG2@.152$/@E@%69CAH/@*#<=82=*&;""?(0GHAG#A84!.,91D$(G'#38."H+$->-,#B3(<GA6H'$%!?"2@*:"<?>H4"E@.9
@r7035
ANAACAGCGTGATTTCCACACCCTGTTTCTCCAGCGCAGTACCGTAATTACTGTGAGCCATCANGACGCCGATGGAGCCTGTCCGGGCGGTATGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACGGACCTGCACTGCAGTTCATGTCGTTGGCAAGTGCCCATACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTNTCCATATCGAGCAGAATGCCGTCCACCATCGGATCGCNGGCAGCCTGTTGCAGACGGGCGATAATGNCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCNGGCTGACCAGCGTGCCGGACACCGGCAG
+
&!&+))%''("%'%$)!"($'&"+!!#(*"+!!!!+$"!&&"*"$%*)++($&)"$)&(+*'((*%'!!!%"&($"(((""(!)!('+&#&")$$!$+&*&'%&!"$*)&$)+*$+(%"(#!*!$""!*'%'$#+$%"'!'(#'%&()('+*(#%$+))!'%#!$$+!*'%(($*!!$&'!)"*"'')$!)%&&#$"%''$("&+")%(+$(($%)%(#&#))%$&()#''+*"&#*#!(!$#%"(&!#*!!!*+**"(%((%&!$+"$+!)"$*+!'#"!*&"(!&(""$))))")%"'#'$*'%%+)'%#")$!+&*+)')($+&)*())$*'#)&*(&((()#!("+*+&$('+&)!'&$(('&&+)(!#!!"$!+#%!'')
@r7036
NNCNNTGATGCTGCATTGACGTTGAGCGAAAACGCACGGTT
+
$!!#')&)%)+&*)""++'(&(&&''!+$)+'+'")$!(&#
@r7037
CCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGC
+
(1?D43;F6:>5E'G<9HAD@GC??$),=7?6$>)8):6!HG2"1
@r7038
ACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAAGGTGATGGTTTCCTTTGGTGCTACTG
+
CE(9)20:0<+9-/-85DF6F9.@.0:,%*=D471E&F7,@79F6<F7/+C77-1(*A@#>%+677:/9F+0>)78.<?512(7<E/B!#>8;+?6."H+0'481/-*#*02CE#6?85:B.8!+'2@@2:9@(%61G8>:8B12-)/A"@B;DA?B0*;BA7G<'D6@0;%B5,+:4>;H3?FH1C#:A$)0
@r7039
NCNANNAAGNAGATNNCNGNAAGGTCTAACGAGGTNANCNNCNTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGTGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTA
+
&$##"'$'*)'*(*)"&")"!)!'#(#*)*"*#'!$"$(#"*+&$$'%()!*'$("*!"*++"%'""*"*#'()(&*"'"($#+#+')!(*'!!)#($)%&$#!#$%$%*&%#&'&*#")&!'&$!%)$"**(('&+"!&)+('%'&"*)&!%&(*()++*)'"'&(+'
@r7040
TCTGTCAGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAANCAA
+
?@F!?'G*/++,F/$>=F.6?6H>?-.FA9H?'@C6(9!,*(@C*409)
@r7041
AGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTNG
+
E5C;9-9%903>81"43H>A&BG>13"70,H!8*.(&'.EA6BH2A/84?/!5#=
@r7042
GGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGANAAAGCCA
+
8)--6C,E=B/'4,#>4"81E#-'G771A1'F8GB+"*C,+E<?@,*+0:"#&$!7!A3HD
@r7043
GAAGACAAATCCCCTTTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACA
+
+:*-1AHAH%#>H,A#"6.H):@@FG3D#;1*)//,C.%>@&9=$D9+<30**:*2E+B:@3:#$C>.#<..A$AF$"0E5EC%08?!:C;%'.5>.?/E?.B4
@r7044
AGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTT
+
D#>?@';9/)GB.9962$9<GF>!.B!>9FD(B@/25G">.,+=3@%@A;
@r7045
TCCCGAAGTCCGTCACGCACATGGGATCCCGTGATGACCTCATTAAAAACACGCTGCAATNCCTCCTCATCNTTGCAGGTAAGTCCGATTTTTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAGATGTTCCGGTATTTGCAAATCGAAT
+
-H&/5E1'&+.31H?6?')2*H@6C(&H<;/G24>4,&/$"=5&%=G-F*3=7!$<5G,B04/G6'39><+D><%?&"<99GBDF*G+.*#EB+C'0B;+H3;($<F$%%8=5"-G2(D3<>#/:46A%G/;94.,*4<.!4ED5G$:&H04=A%%
@r7046
GCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCA
+
8)C!*11$6:!1:'!<-BEA01!5;6"?82!@*&(@:#)/8*-*'"G-'C"BB,G.7=-264
@r7047
TTANGCNGNTNTTNNNCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCNCTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGANGCGCTCCGTTCCGCTGCTGTTTCAGATTACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTC
+
')(#%$%$&#)))$$#')'%+#*#"#"()+%#%+$$(%#!))("*%)*&%%))$&#")"$!&!$"+""*"'($$'+"&')&$('+"+&""#"!%)*%&+"&+"$'+('(%*)#)*+#&*!*"%$%$##+!!(+$+($#'%)'*'!)%(###('#!'&*&+$)$""!'+(&!'+"&)+$"+!#$!#*!"!')(
@r7048
GCAAGATAACCGAATCCCNTCTCGGCAAGGAGCTGCTGGAAAAAGTCGAGCTGACGGAGGATAACGCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGTGATAAGTGGAATGCCATGTGGGCTGTCAAAAT
+
*74?135*1(E@6=<+B6B+6D>$H0;G2@@">>@:FG%;ED$D540+()('.G$-(94)825%9E9A#3%H09+8=#0G5/---BC@<6:G#$DB/A+.5#*?..?%5C$&6>;0&B86@F?"!=.;8G(8!29E!:*3)9
@r7049
TGGGAATCCNAATGATTCGTCATCTGCGAGGCTGTTCTTAAT
+
(:3761$@2(3,(5+%'(>11BC#GGFBA5,'&>D"'-B?H>
@r7050
AAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGTGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGACATTACCGTCACCGCCAGTTAATCCGGAGAGTCAGCGATGTTCCTGAAAACCGAATCATTTGAACATAACGGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCATCTCG
+
A-.E!0*<C>$@@,0>7D7.AG9GE!G$<3/04'.28*!8?9&G%8*6<9%+#82FB':-F7F)%><,C>>H<!B&7F!:C#B1F'G?+27'D*$@C?8@#5&A>2E4@&1@</)$8:/$25BBF*"=:"CD#-<8;@>*#;@)2>2?>@65D@;30;*7!>H;@A=6/+1DB#0;3$>E1E:C8C1F3.;8?'F)!7#F1)0D.31F3+7"6'$G;A92%A*&;@>.*8)95/+'>!5.
@r7051
ACACCGTTATGTTCAAATGATTCGGTTTTCAGGAACATCGCTGACTCTCCGGATTAACTGGCGGTGACGGTAATTTCTGCAACCGCAGCAAACTCACCATTACCGGATACAACCGGAA
+
,23,$;-H4<0!+63<4>*A)C18D)3C!825#B;560E#70A<@!3=FD1A&."-".6*%=)?,1.C4B0/2*'"'H.2'4C613$#02('@1<G,.AC?*<<-%=>G%GD$703D:
@r7052
CCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTGGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTAT
+
G,H=*3,5-/EF3*7&#86G@"B<18D#7>$'48@?G0!)2;0!*C6+9?E.A;>&@/&+6;$6A:A>:99'<,:0/FC86>!2',:)81;2*3?6H-%//-4*@/8)-'##'.7D4/BEF'F#@4+3;D-H00(!D-0=%.0+8#=?/*31-!!#!%!$E=C?3C5(*3AE,E&4A(@
@r7053
GCTCACTNCGAACCTCTCTGTTTACTGATAAGTTCCAGATACTCCTGGCAACTTGC
+
@?BED'/H)<H5A#=C441&!@6*:*=8=99-%=-%17E)724")-HC+3'5*B9/
@r7054
GTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGA
+
305&")EB(0F29+=;&8:F&.:*H"=:9<*!,(9%#??*2++=7$+G0D)6)+*C
@r7055
TTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCAGGTGACCATACCGTACAGGTTAGAAACCGTGAGCGTGGGGCGCGTACTGGTGCCTTTGNCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGT
+
7D?BH#*#B1<B??CF(F?,=!+B?.94(6@';/''.C(D:*C2(/.5#60$#3=@EA,=1A8?B72@;:H.GD=0$3H,&'A2)55!E*/;.85%-DF1D9F,=<D;7D08@?)D(C+!=1E>0B%A/H"0:07;7?!#8*46A0;*37*8-5-BBB@/B5:8;9G!'?@C@
@r7056
CAGGCCGTTTCACATAAAACATTNTGCANCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGCCGTGCTAATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAAC
+
6;3B=;)4H;D2FC9F1@E<FD</6F:0AB237@(A>;$?;91B$5%'#F12D'A,2CB(+.DE96F#+'C<!BB60@9;-;<%7==8!-F=GH/-H22D4'E(-24C0%%*5%'<&A?9H#"97D)62:9<CG59D-@
@r7057
ATCTTTACCGGCTNATGCGCGGCTATGCCACCGGCGGTTATGTCGGTACACCGGGCAGCATGGC
+
7##!=='8G(H1=!GB+8&(/51*'</&0HF6-E60D'8D*/?*91;<.GH54%3!F.78&C?8
@r7058
NANCCCCTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGT
+
"#!*(*++&!%++"'''')%*!+&!"()!#*('('%$"!&'$))$(#(*)$'+##*$&+&*$+$'*!!")"#$(&
@r7059
TTACTGAGAACGTCATGCGGCCNCNCTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTTGTGCTGGTTGCACACCACGCAT
+
%6%80+1.B)(316#(4*3&A82E;@*1>D&>*C>C!HF)>$9A,)+.%-75/:@&B,7&:6#<C3=>;&=DC'2F$C5EAA+6:B-HG*&>(.7!/2A,96*G915!@C+4:&E)>$(/9?+$0!=06&#E<%C.3;<47:/F=;&"#)<G5?)6$37FE:>3,&-+&,,G.8.'$EB/G=B+4C;B9090H>),1@2A=)1!2DF4.>CF$2("=
@r7060
GGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGG
+
8/85/</4(,F=21),&'&5,&G@A';FGG6:C,3&5!&$79H<(!%##3=)7,='3.HH;F-::FDB*?62*$G:!E**A$4<">:91492+@
@r7061
TAGTCGTCTCTTTCATATACCCGGGAGTGATTTCCGTCTTACGGTAATCCATTGTACTGC
+
*$0(2'<4&.CE(E!1A&759E3/;<9723-"HC$!/>"*3.8"5.3E"F3B'!C*/#&A
@r7062
AGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCA
+
2=4,4'<,$;7D'<"0(D:22B9>EB3?='445-1@=3=*=$-
@r7063
AATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTA
+
*<4$F!'6*H+2F/>95.6!>2;&A!CD@%;FE9+=D"/$@1%/D5!-GGA(D'#-.
@r7064
CATGACTCAGAACAAGAGCCGGTATCGATTCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGA
+
?C<,4>B$-BA4'6$F-&F(<4-=>C)&620.A5H,27(98B<=4->E:6%EB86F&)%;2#HA85
@r7065
TCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAA
+
D$?!1E6$F(A*.@,;D:4CA8=915&A*.%!+AB/;=C&"$
@r7066
CCATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTG
+
:;!BB7D1(@1E1(-EAC>F53':F&.-64?%B?8*BC9!
@r7067
CGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATNCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGACATNGCCACCAGAAACGCGCCGG
+
/C&'14A.<B-#%8#BE$$F"1;)D0"*0E&0GG>B4/2?&<(2,A>,CC/AA0*>2A6@5;7F63,F"FA$%*,1$6!G:*0)'FD'4D8/:'$=&-)D/3H1-,";D"=9)C()8B566E:*;5,#F:;H4<C963%0>0;/
@r7068
TGTTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCA
+
+D-!D46?$0!8CAECG)9GHG'>432H;.)!C3#=A68/087$549E,E1D'%&B)<A0
@r7069
ACCGTACTCAAACATCGGGTTGAGTATTATCTTNCTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGACATACATTGCAAGGAGTTTATAAATGAGTATC
+
+(''"#&)+%#"$$'&$%+*)+)#)&'"+($"$'(*&&"(&*%*(*%)'#&)&"((&%+**%%*&+!%'"')$%+$&%&+*'#$*(%+!"#!$+&!%$*(&)%'('%)"!#
@r7070
NGTTGCCATCCGTGGCCATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGC
+
#0H=H,)H7,*-1'A6*);(>B,%E%1"7$!!2./EF6>!'.<.@!:<G$46+4:1G59D=):*:4?+E%.79;,5:CH(64>A@&!G-$&0#*#*/35)%.$C3,3=HFCE+'0=:3
@r7071
AGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATC
+
605(5'E.6%)6/B<)?06)5C':(B!3=7A8':,;D@3:A
@r7072
GCGTGNGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGNTTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAG
+
7:0/$#C.,5C)H12/83C"-!.B'65F)D7B3EB>2'A:$7#,"@3$2C,$GA--%+!*G'H'FB&F$&87BCA"*",C(5)FEB8/>!.-;G<20A*>9=%3++!>2<F:F"+F-:31493A&6&)77>CB+H5E$B4)
@r7073
CTGAAAAACAGGCTGAGCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACNTCATGAAAATAATGGGTACTGTAAAAGCGGTGCCAGTCGGCATACTCCGTGGATGACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTT
+
9%,&)$G)<'9&9(9A6$1:,0?0!@4:9B9.E1/>"A=AD"8$G*A8*"*;',FC56>%D$H#*?6=97;11)(-H&3"7&1>&9#6*<(A-81:%15AH0G8F%CF2&+!F&%"!/>8<$(4=9B0$'F=$1<.G:#7A9@/=':9%!$F'/6%#3<'+@.F-8H(D(
@r7074
CANGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACANGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATAGACCGCTCACCGTATTGCAGGTTGATATCAACCCG
+
##+$)*+%#)'(+(%)$)%$(+$(*%""*+"+"$)&&+'#%#)%%&'&%!&'#$%*+#'$%"&%(%'*&!+"$#'""$$(+*&*+!#$)*%$%&""+#)"!**%##"$&)&*%+#)&)*'*!#&*'#"*%'%$(#(+$'+&"+)('#'
@r7075
CCATTATAATTTTTNAGAATGGTTTCATAAGAAAGCTCTGAATCAACGNACTGCGATAATAAGTGGTGATATCCAGAATTTGTCACNTCAAGTAAAAACACCTCACGAGTT
+
F.+@CH/9@+/.;D5.%G9-5(;)#;G9&3,"/E;D!&33C,1%/"8//B"2$%0E&>A(-,2A;8H3E6!E6<-+&;+B42C0(=>/0F)29#G,E7%9H5)55<DA.5%
@r7076
TATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTT
+
7HEE&1F!HFE,C!G-4:486'.E??D2/&,1F1<,$"7BA)9.!;;D@(+F6(!:E;H-$%%7*4"<C4"0+'&?F(9(*7#104"!8*
@r7077
AGCAGTCCTAGGGACAGTGGCGTACAGTCANAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCATGCAAAAAATATGTAAAA
+
%C?$B8$67@!'3DH"H9"$0=="5D$=4244%0B;=7&%=%#@79;+EG#>,&E&5"?=!.6>3C%!9')/6B=.1D*3.?,
@r7078
CAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACT
+
9F+;G"9@0<#B4F</AA"3C&G#%50<'CF-)?26*E9D8#3#)DE
@r7079
CCGGGTATATGAAAGAGACGACCACTGCCAGGGACGAAAGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGNTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGATTAGCCAGGTAACACAGTGTTATGANAGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCGGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACNACGGT
+
/D)6$$02*?9H&7#>'::H6.4A*/E!-D!03,,C/3/&3?;:E!5/@E2>4),1D"4))>:),,G>1<5><E&!F47<5234</!C)@.H14FED0'.4=@8+2:4@*>%?#)51D1>7@$9A=!*%6=>G9&&?!0%H!+7,%B*;7*!'?9164G*:%A#,7<-<F?:6H!*409=H,-0(?;=5"6G*86%'G$@!$*8",9H+D")24GG)AE2".#0EHC)#G>.FF8,)5B/GH7D379!+D@79F&:%$>>H&1#=&<#G+"?9A1;H'G#A@"%DD0;@(<7<7:5=&5%85"D/38$4G-#8):(D"HH;B+2E'0D1>;>=ADG(5=:#E+>.!=6+$
@r7080
ATTTACTGNTTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCTTTGTCGTTGTGGGATGCCTACCGCAAGC
+
>#$.&H+7*4-6/GH6H"B$/E:ED;+#?(7.9"H9#'-)?==B;(B=7$-'G$$849!;0-:H?!95807;>%>@*"?4C*>1>0&98==:?B$C&3C!*29=8B;ED(<!H8)$(:F*9
@r7081
TTGTTAGGGAAAACGAAGAAAAAAAACCGACTTTAGAAATAT
+
'#+#'(&!*"&)%$(*"+$"#"!$""!++(#+%$*$(+)(#!
@r7082
ACGTCATAGACGGTTTTACCCTGATGGTCTTCAACGANATGCCACNATGCNTCATCACTGTTGAAAACAGCNACAAAGCC
+
5F46=EEG97D2&16//7:&("*<AA:.DH%>3G>5D4?B?<!C%..D/7)*$*6;'6140(8GFC67,%%!9@699#>&
@r7083
CNNNCNNACNNTNNGNTCNANCNNGNGNGNGTTTNNTCNNNNNNCTNNANTNTNNNANNNGTGGNCNANCGNANGNGTAGTANNNNATNNNNCNNTCNNNNNTANNTNTNANNNANNCGANAAAGGCNGNNTNNNCNGNAGNTANANNTNANNTNNNNNANGTNNTCNANTTTNGGNNGNNN
+
"""$#!"$#!!#$$$"#$!#!""!$"$!!!!$""!#!"$!""#!"#!""!""$$!"#"!!#$#!!"!"!#"$#!"!"!$"!"#$!$!#"#"$""#$"!"$#!$$!!$$#!$#!#!"#!$$#$$"!!!!$#!$"!$$!"##$$"#!!"##!$$"$"$""!$$$#!!$$!"!"$#!#!!""$!#
@r7084
ATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAG
+
-1C/-#5,:01;H?D92A7>"/)/7CE;/4(7"E$/%!B1
@r7085
CGGCCCCCACCATTACCAGCGGCGGCAATCCTCCGGCCTTTTCCCTGACACCGGACGGAAAGC
+
0F6)&H!F3+%>>'!;$.76(3/2!3,F)6.$.E:0%8-?.('9-+%'C(<<CE%/:(9AC2C
@r7086
TGNGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACT
+
H6,"5A$EBA%-1*CECGH5;C1;>D>%4;2G;@8C#8/3-14<B+-+
@r7087
TGGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAANACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAA
+
=9'/0%#$H%%3?2-?*=;%$>D>:!D!>&8(?"".3(F%A<C:D!'9B78&.*;.:4>C8@EF=!G<<H(-85.!+(C*601213>A-,&,0/),347$;$-$?::/
@r7088
GTTATATGGCCTTCAGCTATTGCCTCTCNGACTGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATNTATCCATTGAGCATTG
+
8!4.*&"?A8F@GC!>B40,"1822EEA'-&@DF0E44,?</36!>7@+*0("::5D..)%2</)F*B58A+>F+<<8:!0D5B@D21HB6E5?G.-0B@H%6D2=
@r7089
GCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCGAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGCCAAGTTGC
+
B9>&0=5'HD:D6=-E/0(/'$2DH5.*).D3,7=+!$"1,-/C%,H=:4!HE2!#:9+<#HAH#A$$7:C#=<><H47C8?%7/%A$G>9/4C9.C340HEE2$8D?&(#)C-;""C1&18&(
@r7090
CTCAGCAAGCAGGGTGTGGAAGNAGGACATTTTCATGTCAGGCCACTTCTTTCCGAAGCGGGGTTTTGCCATCACGTTGT
+
5=6+AF@5HBD;G5120"0E(1;C>%E.001D7*'>(:04+?1=)!3;<6H?-G?-?>.$=>D4-'='&674#4+,C;57
@r7091
TNCNGTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGNGTATA
+
)!*+&!%"&'$&!"$')#*$'"($&!"$"%"*&$#"!)"'#%#*!*(+*"&&+#$('!!$%&*)#!+"$)#(*)&!!)#&#*
@r7092
NGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAANCTCGTA
+
!C!$BD?&=2H/6?<?<HB#'399HF8?(0B<.;"=E<4,EH>9GG+C-);*+')+E9@DB.90#$78'16;<#C41@,75BHE*-.?D94%%FE7)="C-47&2=G>B(?6%<,:5H#$=7$H51
@r7093
CAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCNTTACCGCCCAGGCACCAGAATCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGG
+
'&86<F:#=5'D=10"HH:'<7;!D#;?)E"2E(8$4HA0G"'2$%!E8+,G.,,@7$*#777$;708%A5.:;3GG-B!:GF-E,18C2E26"G=94C97<,84HA+G)**/9D2,,)/7+HG&<.1>0=4CG-@*#D@H+)G!'H2?"0>+CGBCE#)C@=;&&."'
@r7094
CTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCG
+
1--#!?*D+0!8CC@)F#5GG&$<)@G8+?GD"-$D$F+")H*@)#*+F("CH56*"(#;"9+H/H$/?E+:$8*AA(GGB<6)H1,!06:4?>)0?B4F'D,.-,*;>F8)9"5B&#14-;)>C,<%80).=2@',>%
@r7095
CGGATAGTCCTNGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCA
+
,/4'BC%650?-?&$$)<$(692;;@#=>GG85GC16>7*17!&DB&;%(!7B:;
@r7096
GCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCATTAACACAAGAGCAGCTTGAGGACGCA
+
'HA#$)79C=B2G")($1:(!57,4)'63.,78(59$#C(E79;"/)B#%-?.>>5#%%@$)=F/,)/9?/!6"71A>58))+<F'%G6..H
@r7097
NGTCAGACTTTGAGAAGGAAGNTATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAA
+
))8)#<06;6"=:B.-9>9'59F9&#!"B4'48&8/=-.EGH7+39$>=90+84)3F)">F,
@r7098
CCNGGCAATGAGTGACTGTGGCTGTCCTGACTGTCCGTTTT
+
E(D%5'@,*/5$0<8%#A05;1-8$6A8)82<;*A)B@=%>
@r7099
GTNTNNTGACTNCCGNCAGCCNTCAAGTAGGTGTTTATGTAGATGAAGGTATAGATATAGANTCGNCATACAANTATTCCATGAA
+
&&!(&'*%'&%*)!"""()!%!(**!(#+"&$!$&"%%%!%&(++!$((*&*)*&)$&%(!$!($!&#'&""#*&&"(%$#'$*"
@r7100
TGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGNGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCG
+
&+&(#'&('+"*$$&+!)+*#$""*$)"$!'+$+"'#++"!%!#'&)**&*&)*"*#$%'$&&!(%*&)%#&'+$%"!)$&'**'!%(#"+&&!"'!#(##*&(#$"(+#++)+!&+)'(%!$!&"(#)(!$$#)
@r7101
CATCGCACCTGACATACATTAATAAGTATTAACAATATGAAATTTCAACNCATTGTTTAGNGTTTGT
+
D>."B4A2G(:HDB:%B-$;6<DBHF&.?.E*AE+6%7802?A$A-E@;$8=2@F(.F-:!5/>/?0
@r7102
TTCCTGACGATCGCCCGCAGACANCTTCANGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCC
+
+*&#(#**+!)%$)'$"$+%%(+**+#+'$(%'#'$$)&(((%!##&!%#'&%##*%%'$#$&!+%!&++*'**%')!#'%*$'""!()+$("'+)$((+'+#$&!$"%*"+((&)$+%&##'++)#")"')!%**(()$&"$&(*#*&'")!!!#+#)&+!'#)$(**")("!"%#!#!#%&#+"+#')#"$&)!
@r7103
GNATTAGTTCNTGNCTCNGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGANAGGGGG
+
$%$$#"'%(!!'&#*#'"(+(*##$&+&)%#&'+"&!"+#"&&&+)"'+*(()")')&)$+(!+)*!*)*!*"%"$))"#$***#$""')&
@r7104
GGTCTGGCGAACGGTGTATTACCGGTTTGCTANCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGT
+
.6!=1H,%3/F#.<)E+D4!92$-A5>='6@/108$=D<2%44D-,'FF@@(<@)#+:5)63A3%,F+4":2*G%;+9*:C6@
@r7105
ACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTT
+
$D@14G<7G00*!5&16CA'1FGC?HAH9<BH08!*E89=-0.+&GC9%$9)B6GF4+5/.:=A+59F4E>G9C1'"',C@8>0&CD8?19C9?/7A1B!94F&A0CC/%1-4%@5":2G-8G0?$A
@r7106
GTACAAAAGNGNTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACT
+
5B-4/!00+!.;@<.G&7(#*.7A*%5=7E(-2;F3)D/@#A@:7.<0%2&'2@3F4.>:4==A(D$.='&,-5-D@:;4-$0>>
@r7107
TATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTA
+
%4F2F.F?681:-1G731=,0D,';5&A7,#-5;?G$<B3-G">:G*H3G
@r7108
TGCGATGCGCAGTTCATCGCATTACTGATCGTTGCCAACCAGTACGGCCTTAA
+
('%)+'&%++$!*)!)()%$$+#$*#()!#''&!&$'*%#+*"!$!##+##%)
@r7109
CTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATGGCAG
+
),%%?EG+AHDH*>9;,&24'0A%7%3@3)?*0A0F=+"3D-*13-;C>H3=2',--(8B7>G'90"H=5F
@r7110
NTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACNCGTGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATA
+
$HC.$&#;HH!8?EC"5*6?G2('="1&;G@;?&6FE6+0(81H*&#7!*!D#DAA<*B,63"+?H!%>+H#31:H*?EF;+''*5:'#4$"80FD57FH'DFG@'/4CD?<B"25GD3+0@,8:./<52B78?698?!9@7=13G)AH+6.>):?'B!#!4H78A9"+")7$$,*>/2?#;5.?97;,%3A@-CF#5@F
@r7111
CGGTGAATGCAAAGAAGATAACCGCTTCCGACCAAATCAACCTTACTGGAATCGATGGTGTATCCGGTGNGAAAGAACACCAACAGGGGTGTT
+
+*0A'/1'"/E?9)D./6!HG()2,C:H/G*41,H-(="B2%5@=%#9$<2&<G(45!0<0*AB#BA6++B=5(B:6F3-&C?01/((>@4!,
@r7112
TCCGTGAAGACGGAAACCAGTTTCTNGTTGTTCGCCATCCTGGGAAGA
+
+%$%+"##$%*&#"&$+&&$!&$'+$*&$!'(#$&+''+)'#$*($+)
@r7113
ATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGA
+
$87%'8$FF*)5+99"?#!A;>8*E$7C0A:-HA67+-".7*GG,18.6+?<%/$"-H?A)18(#9+?;GC7A997H2%
@r7114
CGACCAGTCAACGTCTGAAAGCAGATTCGCGTAAGGGTCACCGCTNCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCNCCGG
+
12.=FB&&C.G8F+3<DFH%$F344?':.#:3<5=8@@&).&A8&1.7.A:@F>FF:<--0"1:4F"#E/;?E?/,(9#(<=!G5!#3:
@r7115
GTTAAACATTGGTATAATAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAANTGAATCATCTATTATTAAATCAGAAAGACGATGNGTCGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTAT
+
0#A"*9)@">>E%D'@E*9&D*3EAC.958/G4&H>1#5E@H9F9:&#F.&$H<+:HE3'E,*A:'#B*@C03@BC>GC;C7*6022?0:&<CG;A8#"8,'-.+;-15&"A187.%D9G3:E;/G.*;=42>B"@<BC>#,$G=!6%)0&
@r7116
ACCTACCAAACAATGCCCCCCTGCAAANAATAAATTCATATAAAAAACANACAGATAACCATCTGCGGTGATAAATTATCTC
+
BB8&-E#0G:$0<,8$2EC8)=/66/&;=C*3=H!B21%>18)H9B4!9B-H/;GF*F*A67!"9$2D1.FD;,HB<=.-/<
@r7117
AGTTCACCTCAACGGCATTATGGCGGTCCTTCANGGCGCTGAAATTGNCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTAATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGCATA
+
?'#?66%1(-.G8C6!!'HC8=+,5!<6+<G4G,8D&BH,A#)<.*#B&FBB(;B@C+2&B+:"81*E.>&@.>+$,?9%7G*,22=DH?A)A/H?E!>.334!*@7+D6.E*5$-@:)2<-HGH01;7@F#F*?!$61=,86C/#3B(DF)&EGD-2:(BE5=5=:.
@r7118
TTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCC
+
44/72=:"@+#,'(FC*E66-0:/G7!5#&2>>2@8(5D(H=!@E"29!.0;4.(>*0;:'G)!G/2C3:'>A1AFG6'772!4:
@r7119
ATTATNTTGTTAACGATGAANCGCNGGCGCGTTACTGGGATGAGTGAAAAGGCCCGT
+
=3?-87,5BA;GH6B0"+3-?:'<?-.7'%4>7/0G$C(56-5B%08%=:"@"<4-:
@r7120
TCAGTTCGCTGCACTGCTCAATGCGCCCGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTT
+
'3:H6H;7>C;*1@+B+G;@)1"'AFFF?$--".2GE4*#<*9;13>C7+&)+E(277(,G50EE01(
@r7121
AGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAG
+
;1FH-4*4.*((+4!?<@+BB<>4#G<#7G-#4)%31HF7@E=)%?G7(11?#
@r7122
NGGGGAAGTGAGTAATGAAATTATTTCTAGCATTTNTCTGCATCATACCT
+
/D*A7:>3#;B@"38:(.?1D5?+:):<9-&A@H*$!2/<46F=9/D:BA
@r7123
NNTGCACAGCATTGCATATTGATGCNCTCGGAATATCAATGAAGGA
+
%!%!"+$!+)'&##$!"%)%'$%)!!*$%*&&"(+*!!&"%*)%'&
@r7124
GACAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGANCTGATTCGTGTAAAAAA
+
;C<'C*6,:4>488?BAH//5F-%&'*1=:D"GC2=2?1>'=8>?C#?&8&.<&E*;*0:7#
@r7125
AGGGTCATCTGCGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCCTAAATTCAGAGGTGGA
+
H@H*/,<=!7#BB3&'@),2!7$C<=:56;1%+>$.7@02=#-#54.,0"4D8?$"D!<5F2F-%
@r7126
TATAAACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGC
+
<?&-E5FHEA>'@%1F:/&'C58G17?'3-;/6:*2@9F0
@r7127
CTNTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATTGAAAAATAAATAGATACAACTCAC
+
/%48<ED"F80%B/DF/-!:%?C$5B3D5.!(;0,4=A:A8.+H'B6B9@(2('//$ED&4=F#,E$1H/8!ED53F0"AED-:A3$AGE+-(25'@?)@@3;:(+*8G)6C4!+(;"2C->>B&;$&)6*5G*#(B';"C72DGD%33#G#."HD-5G+<%<
@r7128
CAGTNTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCAGCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGG
+
57H!4"?>B.?93B9>%@9&8=%0?)6B;B)E<7>+3*)@03'/07#$%3!F(!#&<CG30549!>2G7=<*&C6?5>B2!)-H,2DE$?-*%6G%F0,F'2#6B(:->58@*C,5C*(;0F(-5.$C+55>+B"0;A12-@2H>7!.>/::"C)*;>>BA"9+-*-0!*B>E"3#
@r7129
ATGGCATCAATGCATTAAATGCTTATAACGCCGCATTGCTTGCA
+
?G2)$H9.#>:!6:1D2H"C#!40#&>#6C5C$*(6,7@80E8>
@r7130
AGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGG
+
@E.@&$@4=8C;D"0+>5;$-0:!3(3@B6=,'1?E?)8!@4"+61(H'D3((FE"2#773.E),.A7=BB@,6,G(86/?.//"<,$2!/8&'G@8FE?,7%'1$,9
@r7131
TATTTCTCCTTACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTNCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCA
+
F0#*(AH<"GH#030G-$E@9-0"DH6"*3&+8($!B-0G,<@G&*;A/3"1H#$-.$#::4=H7DH+5?-?"3&<<'@$?'<,H%GF*2<@+62(.#'>4?%
@r7132
CCCNCANNNGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCGTTATGAAAGTAATCTACGAGATAAAAACAAACCCGCTAGAACATATTACGATGACATGCTTGTTNCATCAGGTG
+
)'%(&'%!!%+*'#(+"("+&'"+#*$$!!#(")#$++##**"'#$!*'*'#++*"'(*#)#*)+!"%)()(!)!%)%'&()#!"")**!'')"$%&'#'&%&'$$'*!*)*)#)&"+*"#)*""!""*$&$($
@r7133
AGTCAGTGGCCTNAAGAGACGTNTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATT
+
&H5!.(D"'H<6/.@05"A?7%';!9-1&!8G;H:98(#,".C7*+23,4%B.9>GCD/;29,A**.%'D%7:-"1*A%BA&"EH<.4/G)1
@r7134
AGCCAGACGGAACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCC
+
*.?9.&;/*C-&H02-)?5.EA!+B.4;2<40/F";'*4=F)2E2?;C.7H(=9F/
@r7135
NGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCT
+
$+!'"+""&%"(%&("'+''#'&$%)%'#'&!'!')**"%#!+')(*
@r7136
NNNNTGGNAGGGCNCANCNCTCCGCTGACCGTNGCCTTCCAGCCGGAG
+
%$#$*&$%%)#)'!&&#*!'#+%(*)#"'!)"%%!$%+##)+("#&'+
@r7137
CANNTCGTGTNNGATATCAACATNAAAAGCAGCAAGTTCATCATAACCCGCCACATCAACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCAC
+
%##"#)$&("!)""*))*"#'"(%+(&+"$%)"%#)(%#)"&%$!#"!&$&"'+%%)#)&)&!$!#(*''*!%$+$(&$"&$#!'"#(!(%"#+!(!&#(*%'
@r7138
CNGCACNNGNNGNAAANNANCNGNCNATNAATNCNTAGNAN
+
#"$"$!!#"#!$$$#""$!"!!#!#!#$#$$"!$#"$$!#!
@r7139
ATGNNTAGNCAANACNGGGGACGCTGAATGATTTTCTCTGTGCCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGA
+
&&*%)%&"'*$"#''!('&"$(&+$&&$""'+%((+!"'#)(''#%'$!$)""++%+#"*!#%")*&#$"++"&"!*+++"%&)+$%*)%$+!&%$)#)$))'&#'$("'"))'%&'*%#(%%&'!)))++#'$'*$%*&%"'"&'+&$$
@r7140
CCACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGTGGAACAGATACTCTCTTCCATCCTTAACCGGAGGTGGGAATATCCTGC
+
1%7E>+1037"D"?903@-2A7+E:</>#8C1$@%A';7$1<D$:,*55!H69DCG.&@C"=-4G";-!*GH,/D)(C,6"F=,52/0!,4FCB
@r7141
GCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTA
+
)*-7>*-&,CA(F9=G(6C(1.@!1>(6==8F.)8)5"$?77<(B76$+6&%',G3$.(+,:AEE890/12D&.,F8&;!@D6H,>1A&*&E%'FEA2,
@r7142
GCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTNGAGAGTATGGCTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTTTCNGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACATGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTCCCTCACGATCGCCCCCAAAACACATAACCTATTGTATTTATTGAAAAATAAATAGATACAACTCACTAAAC
+
+##+*&)#%'"("+(*&!&(+%')%$#&%('!)!(%!%+"$(!&''(+$)!#)*%''!"$$'+%'%%%!(!)#()'!)%+#)*#*'##**!%*')#(+"(+(#"'!(+(#*(#&"%%%((!%'"+%%&+%(#"&#"")*)*#%$**)$)$%&$)&+&+&#!$)"'$%%*"(!&!%*'%"!)&%'$!&#&+#&#$&$$&&#%$*#$%%"#"!$$$(&)!)"##))&)*%&'!+++$'!!"#(!*""(#!*+$(+($*'(+!&'&*%''"')+*"%)#$"#"')**#($$(+($"'!%"$%)*%)++!+")##*#"+!("'$#!#%+&&%*+!#&'''$'**!'((*!"")$*")&"&%("%($)(*)!'%((
@r7143
NCCNNATNTNTTGAAGCANATCTGAAACCTATTATAGATTTNAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGNAGATTTTNTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGACTACTTTTTATATGAGGAGGGCTGTTTTTACAAAATNCGGTANTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAA
+
"'&"##'!#&$%'*"$((#&+%!('!&%*&(#&(%$%)+!!!+&!'%!&*(#(""!(&''*'#)'*&&)*"%&)'&&&##)&"$$%++(*!)#(*(&')'!)*")&")&(%(&%#+"%+#&+!+!(#!!)"+!)$!(#'&'(%")(*"(%)!#+'("!(!*((&((!()%'*)!*+'+!%%&(#)*"&*&"$*&&)"%((%&&"!)'#"#&*%)($))'"#""+%"*%"$)+&#%)+&&%!'%"$)*
@r7144
TGGCTGCCGAACTGCTCCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCANTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCCGGATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTG
+
7,1G+873(1'AE,*,-A0;6)<><?;11.HD;6.8>4HB=03&)FG.1G@BHG?9A>6*($A7;)036>C2F1F'C'+:88G/F:H@:>@#+*39:G-&:<0E1.&/F%)")F->D,7?#@@0%;/*C=%";:H%7<.-@2C<3?$6F//D7@(F(8@F%/C6;E32GF%*2D>*2=E62$;&92/6>'=96*+-45C"52H=9/4'#$.%(51+&>6A4'>2D+!&"CH!H,"&A%CH:0/B%"?C<#46!!C40BEB4D,<*%!2'@A?*B!G71EF;B$C;>+)G0?!D274%1G966@4BED+%/-4'E%**-"BHB">""#'F+$2$<(="EAEG?+*G*(#/"H.:3)HB;.73,#G*<.E>-
@r7145
GGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACNAGTTCGATGATTAATCATCTGCTTTATGGGCAA
+
H;#B4(8#:<A9,<3<'0-8:BEF6B$B72F1.)A-'(<@5C$6/1=99+D?2-%*!'*+)+'>$%1C>6::1@7GD'
@r7146
AAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGA
+
FG1&!,492E(?4"2H/G9H1?D%@F%$(0H'/&1!5(E/3F>#1A&6")+)93DF9A5
@r7147
NCCANAAACGAAGCAGTCAGGTANNTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTT
+
#!(*!&(&*$)%*$(("&)*&%!!$&'+(*+!#&#!%($'%$)#++)'*$)+%%"%#$&*&
@r7148
GCCGCCACTNTTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCT
+
9>%&>+<(07":A"8>;.%;B2$&HC#4BH!=:4%H+(292%EA"$2#/0FAB?&<2A>-9'$F"D3G*0*#81F.?89'2!"1C@41"0D8=<!#G5DD=42+%EG58>'F:&:":>4!%3H:5>#7-91/3.(6:76E
@r7149
TGANTNANGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTNTGGTG
+
%*#))('"+%(%&!"!#+++#&+"##%($''$*'"%'&'*'#()$*&$)!!#"$&"(&'!*)#%#
@r7150
TCTCGATTACGACAAAGAAATTCTGGCTAAAGCACTTGCCCATAAAGCAGATGATTAATCATCGA
+
A@,<;<-="7#39."E#*/8!?3'8>H?4"H01+%>D=!4.5?1GC97&>..$H$+%<-)%!%H'
@r7151
GAAACAGGCTCAGTGGAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCG
+
(0&5828A0.:B5/)2F2%?4<;?6D(92)#DG%DH)2F#1:.9"$23B5'G$$,?;5&$8.<G'*
@r7152
CANCCGGGNACCTGNATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTAATGCACTTCACGCCACGCGGGATGA
+
)&%&**%#%#&(%!!)+++'))$#&%#$'())%!##*%*(#("&'()+'%&##*$!(#)(!$"(*#)"&((#&#%&!+&'+$&!"&#(+"%!&""
@r7153
CACGGCGGAATATCTCCCGAATGCCGTGTGGANGTAAGCGTGAAC
+
+*%($)$$%%+%#((%!)%)++*"('"%%##)$*#''%(##(#()
@r7154
AGATGAGCTACTCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTATGGGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTNCTGGCTGGAAGAGGCCAGCGTTCGCCGCNTGGTGACGTTACCTTCNAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGA
+
?C,7C;84(E):.F"@43$,==1'C!F"9/9=!+D:G6;%A,%40'?5?H>>8"C(2@6291%-):21-D47#4+)G802G71D.>A"0',395C"@*A#BD%D)<-'9"B(;B+>'@HD/>D5B)@:.!F(,A5?D5'F264&?E0*,#;5=!G+"(:99'@<5EDB'E,4?D)6?BD.G<?6.$F)G*C=+277&#50F+1<@C1@1&)A$4/-5=>;H&6<6+<57A+(=,*2-23/+:G7851+&<3A0HHE@D!::36=%#/*/7)?7(>H5-H=)1C2/'82?1AD
@r7155
TCNCTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGTCCAGCTCTTCGTCACGCATGT
+
G55,159-D?6F"7)H<!%769)$HB2G7-EE!9:,D0FF$D<!=DH9(+-F0#<AA41;"B-8D)=<HHA?H0H3H7(6/54GF???:@/)H+7D4F8AB?A1*4B)))3@*+/'B88E*"#$H:?)A$
@r7156
ATGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAG
+
'?G8G:*CFG2>@'B94EB-9*8?2&A@<)!&74E/-?/3H>4@)EBA+:2
@r7157
ACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCNGACGCCTTTGCANCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTNCCATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATAAGCGCATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTNCCTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGANAGCCTTTTGTTTGTCGTTCTGGCTGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCNGGCTTGTGATTGCGCCATCCCCATANCAGCCATCACCTCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAA
+
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
@r7158
TGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCA
+
2:7(E1?:=:-=!F1A''G"2#B;398$,10A;8)87>&!:+?E.";9G0A54"H2.2#G:,'>48'!@,<@FD'">:8F79,40<"5:
@r7159
TGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTNAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATT
+
-E(F93!;14/=+F*07;@+A-0.'(:"#%'6??//+'6,E=.?9($&47A6#7>G#!56'H1E$$%17B*(D2$0*AE-)"3;&@H)6!&&9;5<GG')BD"85<#%*!?H&$D=1HE0,&97,+-#A/E63F8"1G,H7=,9%7%32*@.+H=$H;(8@.+2.'6#??.BCC<7*HDC>
@r7160
CTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCACGTCCCGCTGCGCC
+
B(E69=:B$1(8*%6B%>1?&2H7G.-AF6-.@C!-!,?+/H*#$5FGC7-?*#
@r7161
AATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGGAATGAAATTATTTCTAACATTTATCTGCATCATANCTTCCGAGCATTTATTAAGCATTTCGCTATAAGTTC
+
+04?/9H->6!:'G'B4D*:1CCG)/37/*8+H,22BA1(4<%%,/*,$=914?;=3A$?$%/=?*@E$BF#/7EG:@5>H6/$!"C#&0?G@92H+E9?9<-D!1.2!($"(!HC*&
@r7162
TGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGNCACGCTGACNATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGG
+
*8>>/)+7#!1-!(A=A#9)1#.FG(G!C<5+7.?*.58"$5GBE!<8.(93+-<?D&6B/D+">E0!A!?E=>/-19%9</54'C.7/2/,)475.>#
@r7163
AAAAACAGGCTGAGCACGGNGTACGTCAGCCCGGAAAAGTGCATATCCAGCAGAACATCATG
+
,H=$&7D>05AG'#.':3!3'8!FB@<?5!D0>8'5/;9;6)E0ED&'*0G36&H<&)5@>"
@r7164
CCTGCAGGAAGAGGATGGTGCAGCAACCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGNCGCGACAGGAAG
+
*&+($*%#$#$)"*+'#!&(%$*'()+#!$)#*+&#'&$#$+('('&!!&%+$+*)")$$&*'#"*!+$&&)&"'%'&)#+%%%$'$*+(*$*'
@r7165
ACGATATCTGATGGCCACGGGATCGGCGCACCTGCCGGAAAGGCCGAATTCTCACCGGCCCCAAGGTATTCAAGAACATCTGCAACGGAATTTTTTGCCAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGG
+
9((4C1@#,$0>>)+4'6)"%&?%('>&>'81.6?E*1533-*9#0#:F7%>FB(%*E)$)-=-:.)/+!")&6E.&A&-?D!#D3:'0"4"%92F:41@0211=9'G8GA@,+'.-)9)F?=BD9#EB=/4*77>&)8
@r7166
TCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCAGGCGACGTTGCGCCGCCTCCTCCAGTACCGCGAACTGNCTCTCCGCCTTCCACAAATNCCGGCGCTGNTGGCTGATTNTCTCATTTGCTCCGGCATGCTTCTCNAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATCAGCACTGTCTTCCTGACGATCGCCCGNAGACACCTTCACGCTGGACTGTTTCGGCTTTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCG
+
+<E(G34;"5+>=*.BH&)=D8+DBD7"HCFH,9@5D=>G/$+?6F;'6G)C%&2D#?:B%=G1?2H&2<?,E=A;%FB"#./'?5:24&1*A<3$=800/??44G;'+$G3<."3?:G'H9+4A/==68G=&(#"*C*=2H/F/!+1+!&FE:C1;8C1D4%319=)CG,;"15?A.;+>)<"#5)=6)"G-$#&'G'5#-GE#=<-&'09B%@>&<GF-0,.7E72(<?).+"22FA!5$D!E1"08G4F">+&-$@=!&,*E'37F+9/?36//E7>'%/E8"
@r7167
CTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGT
+
HA5GDA?A#(6*+;,<">E+9#($H1$9D8*A:7!8#4@<,HG&1FG/.=5%E*-DC!A2(-;408!+:75;:CF-F#3C7942**3-"D17$F'
@r7168
TAATTTCNGCAACCGCAGCAAACTCANCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACGCTGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGCCCACGCCCAGCGTGGTGCTCTGCCCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCC
+
*?<!0E3"79F<*?%6?/G:.&5/-&9HA49")/6G:8/90+5;077A<>#E?F*+4(@E.$<=1@(-9-0BF8=-4"'6'4>:12*65/H*G;C>A4>/++G;G%@$=41/?5(@.,">*5@*!D),);4@EC;--C&==3$2&AF%/(08B9A"'@/F,/'1C=G5;C-9,9''CE:GA$7'?6/9E#0046'6>#<H0,"04:F)CB!+/B3B4+;<G->$FH>/.D,92#(-H4
@r7169
GANAGTGNATNCAANCAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTNCTTTAGCGTTAACTTCCNGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCGCTTCTTTC
+
&#!)&$'$*&(+&!#'(%*$+*#*"!$+$(*(($%((#*()""!"!$()))%&!$+%+'+$&)$!%)'&)*%'+'"#)#%('+'%*+%'(&'%)!$+++$#'''%"$'#&*&%*""%*(+$$+")++%)*)+"#$"%"'((#)'&%))#
@r7170
CACACCCTNCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTNACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAAAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACT
+
3A)2=!)>:+*D?',42B/3B+199948&C;!&2EF6AE:(-F2-/"7*6!$"%''<023!"$.F2*7G&=-B.=$;=$*&0.,;&4=$.6-.3'>19-"?E6D6&0-DAD?75@2B#21>$7"@1"'9
@r7171
GTGGGTGACGCGAAAAAATGCCTGGTACTTTGCCAACTATGACCCGCGTATGAAGCG
+
C';*(&B1)3=*>4E*>!+9G186%/7;6B$2,+C/,;%0.'$=,$!!H&C.F'C=7
@r7172
TTCCACGGACCTGCTGGGCAAAAATTTNCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTA
+
*)&#+(+&!+%"&*!!##$&!*!'&#''#$(+)'!)'"))!!'%!*'!+"*!!&'%)(!#!%##%$%%##!
@r7173
GCTTATCAAACGCTTCGCTGCTAAAAAAGCNGGAGTAGAAGATGGTAGCAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCNGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCTATCACCCTCGCAAACTTGTCACGCTAA
+
D'(3DB@-8$!%)))-B/,3G"69:6%30+0D:!>/"#$96%3'GA9+.64H$:@B+7>"1-+='H/4;E366?DHE.:3FE.<EHH5C9$46D&:E'AG38--/2/0*(03)$6/7;-<78,2F(9/&?F=G!C+!9.G=,?@4!%B,:G/@+"<.+'E&6<9E@.$&8?0E'B/A'&G3H+%*1;F:=:CG)7&@&8+E!3%4A@
@r7174
CTTTACCAAAGGTGATGCGGAGAGATGGGTAAGCACAACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGATAATTCCATGACCGCACCAACAGGCTCCNAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAAGAAACTGATCAGGGATAGCGGTCAGGTGTTTTTACAACCACTAAACCCACAGTACCCAATGATCCCATGCAATGAGAGTT
+
4@(/'E5@,83E4<715&9;2/':<E@F:9%-$D,$=C5=@2"'#<H--6*'&3%0C9>.33"BH611=HDB#868!8+!1(&2G)GG'(G0(#/0-.&:+>!&+A.+203G/07E=:+@E>B9:"?:79307*57:,,'.,+&@5E"1=,D'6D:?!)/;$BF,).8)3EE:-H9&FH,>)&&9=446?'F.9A;93F)";8,&;$;$!'B6:564*DG@H>)@'!1"<>F=84'-5@%)F7H56<8><!=2+C-5C2;%&A,35-,#70%26(#@D-:#0--:/?D24=F#(B/
@r7175
GCGATGAAAAGATGTTTCGTGAANCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTT
+
<6CD3>A,!*-FC>.?%G#'4GD)3<73+7<?H(:E9($43?G4CG0GHG+1G0=?;3(3;8-:7E84D,B:D=.(%*#3,6<>5?C:';:+2"/<
@r7176
AACATCCGCTTTCCTGACCAAATGATTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTTCNCAGCCTGGGTCATTGANGCCTGCCGTCGGAGACTGACGTCAGAAAAGAGAGCATATACATCAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTCCGANCAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGNTGCAGTTT
+
+!#(!!$$("!''()()+))!%'+(!"!%'$)&!$"+$$+"!!($*+"'%%%""#$(&&+#'%)+#)"%#&#$+"*#(#+!(#(%'$'+%$*#&&$*)((*#!)(''$%(&!(+&%())+*&%($(*)((*#(*"'"$$)"(#&"%&&$&#!'#)%!))!%"'"*%*'&+!**%!$*%!(*%))&''*+)+**#%*()*&%#*%($(#""("*"#((&#'**(%&##)*$*""#&!!)%%
@r7177
GGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCG
+
:8.?)7B;("08)FE6=(3*#8>>3/(.:ABF&+%2)*C4"5;F5>@4"5CA60)6,+
@r7178
TCGAAGTTACGAACAAGAAAGCGTCGCGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCANGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGNTCGATGCACNAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCG
+
*+'))+))%%&!!"*&'(%"#$$*#!#*%'#""''%%)%$("#(!"'*"("#&"*)%$($!'*##&#()'%)++&!!%""!*&)!+%(**&#%$*)&%%#(%&$*!&(#(*&$&)("%%)"#&()+*'(%&'')#+#%##++"(%)*(!(&#+('%(*+!&#+!('#%)$+'%"&)(#$"$*'!(%"!*('$!
@r7179
CGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGNACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTN
+
24;'/)%9*;=6B;673%);?*,E%9D8:F!%#(+>)H>-DB4%5(H3D*7)G:HE*:);E;H8)>#834>1%&@>;DH3G'E$!<F*G4,,4.@G!#!%GB?D&(!HE*"8,-E5?52/:+E0D)/+F!(B-,EH1+/>4F@"B,HH&9(58&7H3#$6**602";8>C.D*A?-FED@+#4A6D>/=%D<E:.3C#8"<*=$-:+8?2G*6E$@+6''6&D87-0=)(3:,,86/>4
@r7180
GCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTTTTTTATAATGCCAACTTAGTATAAAAAAGCTGAA
+
H+-*'G18BH6E68=,%07(5E#A)C@<2("<A%.1B.+1*/7#*"0C8@7;HF1":877B)>48@/.6,"F%4?BA,A-:G#:/$B",;$*H,F?A($&(#D:;&36-)#+49*!B26G=8;0
@r7181
ATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCG
+
>!%,06/E*9"E!%=?'+@&1?7535'E@6B8<E4:G?47'C)'*.<!%H6F"98'=(;$5G>8%2)?0<<:
@r7182
AAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTA
+
.%E*8?-#*?;=:E3@37??9.7G3,.0E"+G,;F&;><E2@+F@75-E1'"F7,E;3)@27.&)@B*7G@D+B3BDGA+&3A::D+D2A64%;<1?DD"1HD9-=3EB&("(""H*3'
@r7183
CCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTGGTACTCTGCCTTNATCGCCTTGCACTCTTCGANAGTCCAGCGATGGCGGTTATGGTTTG
+
%+(&&'"**'&%)$*+$(#""(!&*$&"$)#!&##$+"((&&%%'#("#+(!*$%&#!+)!(*(("***$"!)"'$&"&#+!#$'##'#'(#*#!+*
@r7184
GCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGTTCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTTAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGA
+
&$*+$%*)!$$$%*$"*"("")#&$')"!$"#%))(*$*%#*##!#")*%(+*(+#*%&!"!&)*!&!#'&*+'"##"*%*(*+'*"!&%)+**'%)'*'+&%)*"'*#"(+%+##*$$+)"&#"!!&*)()"&!)'*!)&&"%!%%$+*"*'*!*!!)!("*$''&&'+""#+&()+)+)%&)&#*+"%((!($$+"+&(%*#%+%%'(%+!'!&+&)$*!!(&#&&+*"'(!+&)$)(#$"(&$+%+
@r7185
ATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTTGA
+
1BF#E@=4<"3EA<<)F5E;;58(C2-F0?8F).",D<%9)>3=H"#6
@r7186
TATTTCCTTATAACTTTTACGAAAGAGTTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTAGCAATATTTAATAGCTTGAAATGATGAAGAGCTCTGTGTTTGTCTTCCTGCCTCCAGTTCGCCGGGCATTCAACATAAAAACTGANAGCACCCGGAGTTCCGGAAACGAAATTTGCATATACCCATTGCTCACGAAAAAAAATGTCCTTGTCGATATAGGG
+
,.D!?%A>8/@1(+CAE5/36+!.6%4@0966E7&/>@?*37.3'",7'C#)..+?E!HF5*'C*85&.EA4="&)1%=8*HH+"-#:#'%6<E<*-:,!:'9802@9-7F/)>$>9$&GG<9:D*98;'16F;H%*#=,%C'1%?4"'=DEA=?3B"-<E-#165$.!<&%ABE*1#@$'>(E@DCG%>E$.=5?<$1*-G+;%:+,1,=>D1&,5FC8+;>=G.%B-)FH1!84-4#:/,.FC
@r7187
ACGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCAT
+
%3%F3625GBE),1G)*C24G7CH#%*&!-9-D)#E##,=(9;9%>A,77B/G8!6/?
@r7188
TAGGTGGTGTTTTTGANGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCNGTCCCTGTTTGTCCGGACTGATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTG
+
)%('(+(&*"'+#'&$'&*(*+!!***)$*%*++%*(%*$%)+('('&**'+'&#%*)'*'!$#'"++&")!*$'+)&'"%%)#$("(($&*))&&!'+)''*+((#%!+"$#*)!#+*%&%("&##"!+')!)+*$!
@r7189
NCGCTCATAACAGACATTCACTACAGTTATGGCGNAGNGG
+
";:&.=31&;,H@*;//DCD95=G,929/737@66G=978
@r7190
CGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGATCACCGNTCCCCTTATANACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGA
+
52H.(;872/'<-H"3D(@H0H7E2(+(H17+'B8;B(!#5=.@F6H*@D=HF?#=F9-)6-;G)E"(5<()&%>)*#*-D)#&,3#2<8!;#=/,C6GG0A8%5)F,(C?%HC>@*/04@0>1A$
@r7191
ATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCTAGGCTGCAGTGTACAGCGGTCGGGTGGCCA
+
'5702C#1F.*@7.C8H$"=!@6EG5B8A><G-2:6<7E3C%-FD$>%087F$,%)76,;<HF*%F
@r7192
TTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAACTGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGT
+
H'"C0=(.E5C"74)-G*90%">9;9F3C3-GB(!():>5.3,>%E"1'$0B);9.*=H:G)*;F*G(,880D7015@'=7:>6='BB#5$EH:@A>H.F5-:,&0+<H1<64/5,E")#D!0C8;HE-444'@#C&9G'FC7;E.0.#,/:0>?>5*GG/4,:383<$(FC4*<,"<G:!B5)!9,%%/#=7G").(FG3/8"<?=&3F$@854B6E>*0A1:>8&2/&.-+%"3D&=E<#60H>"&H@D&59?,9(&C!H@@79E'86+&E/H*%=>4&(D/,
@r7193
CATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGANTTTGAGCAGGACAATG
+
E,!GE=8+,;05F,$7@G;;>C<H-%$/H=E&9A#6DA$0%H$4/7!2/E?%2:"9B5/&EDC8'-'$@('A.E=G5=!59E9F.2.D,
@r7194
TCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAANTTCAGACAATACAAATCAGCGACACTGAATACGGGGC
+
3:B7&)5?H*:6*,?9#B/:C)A<2BA>18,'2B-&A=?'#@"$G571!)6!1#B+1B!7A((#DG9"'$3=8=$'#(B43:!"D!;D+#B;,;:<%"(;8:14,E$'16#EF?;.?$A+B0G+/!/-*>E/((
@r7195
AGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCA
+
0>)33C!5%$3'B+23/$5D&!+(?+"H0D50<=0CAH2G
@r7196
AATNAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTC
+
&%'#+*!+'$'"!"+*$!&(($'+"!"(!#%#&))'$$(+')&#&'')'!"+"***(%+'"'&('!&')&(#'("$'$%+&#***%))$'""+%$&!&'+$+&(#+&+
@r7197
CCGTCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCAT
+
DB82691")<%#6B>E2A'<'2!;$/0<,!"383C"*61%5<3=#&2.ADD?92,4A;F6=D"1;"@07G"6$4*01*'!0=@#.EC=+"<8'"'3D4>?.@3:C8(A3G/@>?7EE<09,8/G#9E24>0%6"85<F-A>633D'78%==:GF93:A.C(?8%G+-"%'>6<B&=9#B?;D7,G
@r7198
TAAGTTCCGCTGTGTGNCGCATCTCACCGGGCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGATGCCGGACGTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGA
+
39.!,EB1;9"!!>!(?-CD.6B-H?B9C9&/2E0469%$E.F-9E#C<3/1'9)=*4$>H.,(4#67A">#*,2"A,*/)9E,.0A/DCF#F+*DC*7.7#E-/!(,5FE:B-%.+>D48$:=81;*B;@/$>(!G$$EH,1.02!9%C2==5;?.!FD;F+(B-!6-(,B5A16
@r7199
GCGATGCCGTTCATGACCTNATAACTGCNGGNCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGA
+
B0:BF=>%)%*A74A2!-AD(B,@$:7-;;@$8"::'7#7G':((=!':=2:/EF#0E!$#2&3*-E);ECG:-B1
@r7200
NAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTT
+
"'*+)(''($'&&&$#+(%')*##$*&##$&$+)!!(!+*+()#$')!%$'$"$+*+)&)($#)"#+*)'&''"$!)&(&+#!&())&'+#)''*")('
@r7201
GGTGAGCAATGGGTTCAACCATGTACCGGATGTGTTCTGCAATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGATTTTTTGCTGGCCCCGTGGCGTTGCAAATGATCGATG
+
0%7B%E*G>=*?+07?>0##=D.!!)B?+/"HA$->/G)-(+).$$9D'G7D'7":HE.A''D$46"><3-*0'@E6"1;@CE-0-=7H>9)%7.+9;A?B,5#=@>$@",5=%=<!@A53
@r7202
TCTGCATCCAGCCAGCGACCATGCCATTCAACCTGACGAGNGACGTCACCTAAGCAGGCCCA
+
>(5)':18%"/$.,A+%A*"<29$!4G5D*='+..)$:3@)A380+><+*<ECH9F+@;D-C
@r7203
ATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTTTTGCGTTGATTN
+
+1-;)B)<9'6)2+!7/;61;G328$H512'&-22H:(2."9G*(5
@r7204
TCAGACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGGGTACCGACATAACCGCCGGTGGCATAGCCGCGCATNAGCCGGTAAAGNTTCCCCACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCNGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTG
+
7(FH.335@7;D>;5F@@:(75F)D;/#%-F=4EF"-;E*.DC.:$?$*?2AEEG<E%BD"5!9&=8EE#-99F-"H1GG3"7(:65+/!(E;@9-)/>&(($+>,,':1;'*'H3//D85#(-B*';7'('&$<%536:&0G%6%<;"+0FH+<5+?C08B7D>+69D87186-$*F*-"(-,.A/+2.:GEG2,88,019.G.G/E9!2(,:*G!!B6/*.-/5?2&$#'-E1(,,'D+
@r7205
GGANTAAAAGGATCAAATGCACTAAACNAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCACTGTTTTCTGGGTTGGTGATTGCACCA
+
%('"(%+#"(+!$(**$)!+)!*"))&)"(($)##&+&$&+$$$(*&'#$$"%"$"*+$*!&&%''&*(&#+&+&)!$+%(+)*+"***'!+*&*&)%(*$#*&&(")#&*$(!"+"+)!'')('(&)+$$#+#(
@r7206
TTGNCATTCTTGCGGTTGCTGCTGANCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGGTCTGGCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCCTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGATTTTTTTATGTG
+
-F/B,B1C!@60!855&B&CE0(F@4?.06E%5%(H6B&%9#A/C:-=7'.<FE/<"9+4,G+;@A(('(!G%&#!%$!H#8+(3%#%.;/B(:D09781'E/9:6+G(#>#<%"9%A!F50)5*A4,0G5"/'1<,$&84D#$42+6E#6#E$>B!01BC@04CFB90@,">59H!C86/D&0.4C5B.<-7A"B%F7%;>H+9(-D''&C
@r7207
CAGCACAGTGATGACCGTTGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAG
+
0?79B>$,12HH0E6&=*/><78C>4(C24.9,E6&5-2"(E?=>!A1,'!22!5#*;59!8DA'9H(D(9<:.6:3$@A(@CH!('@@<089&!71H4%B;H2;
@r7208
AATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTT
+
1#.:+1,%)?>??:B&';)-?2<-$%37EC*E6(1#5!:;.;2-.=0%=6F$)F3'GG
@r7209
CGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGC
+
.;4*6G;H&.E=1&/&9$F1?@&415*,),1))(-A6#>&'**"?*8:7;A'(HB&8
@r7210
TCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGA
+
(G(-;$F(8=!3&$(E#")?F%>7=@9&.D(1%0,,)9F79=,!*.3>7=,50,637E:!8+@>&5"*9%AG-H@7=A(0$30@D=6+.92"$@4>"/A.(.98B'4/D@((72)$?
@r7211
NCCGNNATAGANTAATCTTTTTGTGATATGCCGNAGAAACGTTGTAT
+
")!*#"%&$(())')((#)"$%#&$"$)$#*+)(+)$!#+)!')+(#
@r7212
ACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTG
+
GH83C1=25!&47;88%A&97/F;#29:5<&7*>9;*/7%*F#@3)>-A$(3A"1"75@!.47&<6#8/C8&*+/(?+=1H8E
@r7213
CAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAG
+
FCC+6D#67D,@7'!8D:E80//BC(,D?,F56(3(4-<=%/2>=3>!#C>8'AG!7$)FBA&E6.%,G;6="@%#GHD(8H/H9'?,)C:/G<2<1>@#)!A&4A8::@
@r7214
CTAATAACAGGCCTGCTGGTANTCGCAGGCCTTTTTATTTGGGGGAGAGNGAAGTCATG
+
$47E;:6$*.2/;C$8;A$-8<19/9=C3>-!590>3-=60%!B,==72<E-=7/H3#3
@r7215
ACGNTCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAA
+
!()"+*()&$""#)#*%#!#()*"&&+%!+*!%)(*++')%*'$%+(+#"%*&'#
@r7216
GCCAGANCCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCNATGGTTTATGCAGTGACGGCAACGGCCTTNAACTGAAATGCCCGTTTACCTCCCGG
+
&0!"?=2F@6#:<"EF/&57:.(*D59$>%D7:!2=9#>H'A15+19?@)24!706B<F(0948+$2A2?':"F4$?"G86@7+&B.%2%+1/);<.@$*'%?%!#!G07/&?!1E53&C673:>5F#;B-?C$#((@B)>/(0*4$F,=
@r7217
CTAAGTTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTC
+
)GFA.2+F)F8:+@EC3DE4,C2(A1;H6EC%8+#5?EFF6C.'2=)-+F69:*G;@4;EH>C$1"(('+D>E0%A=B3F:<!F@E2F%491**+5B((<<-/E&A.4*G1:568D(;'*B@;B<=>A!"B!&%.1CA"1#FG<FAF,!0B">84,710A>!3@FB'@5C(B<D&;@54FD;),/-!:C/4D:H!9+95B.)7.;+"C
@r7218
TGCGAGGATATCTTCCTACTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCC
+
+'F0"':"(H5E8A+(-6H*))>#'F*2'A0";30/;@08>D;79D7.=3686!':8+C/)3F,2.201EH
@r7219
NTCTNTATNACGNCTAAGAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATTAATNATCGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGAT
+
"&'*$%*(%)%"!"+'!*"''!"%+&)##*%+'#'*$"!"'%!&'#$*"'#$)*")%#&$"$$*'(#$((+(((+%%+"!$"'*)##(*%%'#+)$&*$($'$"(+*+!
@r7220
CAATNTAAAGCAGCAAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGAATCGCAAACCGAAATCACTAA
+
"*'(!!%%+#&(#%"%#'"+%""$#$*&!((*+)!%*'"()*"!!("&*$''+#')!&*($&%&$*"*(!*)+*$!*)!""*"'*!!+$*$#"'
@r7221
CTTCGATATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCATGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATNAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACNATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTT
+
3GHF8(FB,-A#8D*E<.?GE*1$7+A,%4$BE99352:-$6D"7FE2B+D,;"D5F@*36:83H5$1$6,78B.G@AH=H8<-*#37*<!229-((8F;D)>@F9131B)CG$CH*"<H9)$C;&!'8@7;&A<-D=>2?,!=%*:-</62B-%2*)G0?B;2>C?$%%2;42B"99-E0CF7-E)$($7+#,1;8<;70&+%:%5(2C5>B)(90*/!.%=+H4=.:+@!>CA0E80(9=&@"
@r7222
NACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCCGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGNACCATACGGACATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCG
+
%:D;1D%:E::DB3,+:2%:@6)5BG!2>;*%)B$9.D"')CB3F7<1.*:%6<;;*,D7%!;F?#27%D(?7H20AC/6!9(5'D#21DF"2B6C<6&9,B%1D1C!6%8&=8#=/1340../E"+6AABD6<5:&?-5E!/FF)%$!72+@:24A<.%G5@/883,<DA3FG1!<>-,G*H46-=<('62
@r7223
CANTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAA
+
$@A2?>1'C,4"(0:9+F;G/D.AEH42F=>G@!D@0'A880'D$G4:DG7?#4A@19*"/,'<1<4B84<<$H+
@r7224
TGGCTCCAATTATTTGTNTATTCATAAAATCGATGGAAAANCTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGT
+
0B9!$'E8>/(&$D/#-:D=;*!"?!><$6,"'B*;-*5+G$*EA%9:G%:E"5*&'89;+@,28>$;BE6H51"G13A6$1,>(>)?61/<B;);F60%F(?-"#<;
@r7225
GTAGTGTTCTGAATGCTCTTAGTAATGAATTATCANAGGTATAGTAAT
+
&0A/4;+$500#/3F,.&4"%E((@)/%!H8)6EED"8/HDD!E.39.
@r7226
GCGCGGGTTTTCTTTTGTGCGCTTGCAGGCCAGCTTGGGATCAGCAGCCTGACGGATGC
+
'616<)$=F(D'@81542>"60G*)0&-E0A!&-8@7>@%->6=F4F,B=!4;H'G0@7
@r7227
NCTCAGCACGTTACCGGACCAGAAGTTGTCCTGNCATGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCAGGCGGATNTCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGGC
+
#>*7:%,;(A!E?*C=0#H7GF5G&'5E=3@B&'A)#1&!4GE>.,'/2(+)>)?A&;0*:,=?><=+#%?04">$9#04)9-8=:F'&<=F/#!.84G#<&-B,HB$D(4!9D%=5-?4G7@""H($<*9A,(())2
@r7228
TCANTTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGNATACGGGGC
+
'4DH''"$/&/C:;1-B.:6-09%0!'6:(CBCB.3.=;76HE-**7C::G<B514GE'GCB'BA;&#9B!>H989-C*3*/GC(:21A=%D0>F
@r7229
AAGATGAGGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGC
+
+(+!%+'#*&$*(&)($+)'(%%+"+%$#!&+*"%(&()#''%"*"#(&$
@r7230
NTCATCGAACTGGTGAGCAAAGATAAAAAATATGTNATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCAT
+
#>?6<$:(1'#AG';@)E-+),2G>.10G!3&$3;%D7.<B"H@6@&*!DC6&-H6G$?9E;?=5G<4$>$.D10B8'$%:3-#$:4;=,4/G/%:6F5,+&)<C;9$G33@+7/@>54C!5!7:27=?&H%.&G9-27>:1"H+(2(GA)2"=E!GB?G@)/;D)64<7+>%4,*/05&B'A($?7"!CD=1H1-(E4>*-$/?FGHDG!A(@H&2F6,:9(>7>@;?>=7/G$24F*=8894&:>$,4-1:C><?%916;"B#F:5#45=;5C(E2-,@6>""$8)*D')
@r7231
GTCTCAATATCCGGACGGATAATATTTATTGCTTCTCCTGAGCGCAGGACTTTCCACATGCAGGATTTTGGAACCTCTTGCAGTACTACTGGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAANCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTT
+
5,>=E-24543):.H%(,G,1"1>24E;G1',&+)2)*""03=%108/G;D?$"8G.C2+H&G27@",7*))&,5#5@D#EH-E$2HB49'2:(369%59;2;42F3%FA//E4B>/5(0%D14?7+(726;:?@6(!!>3!G/6&2G;C"6$>!>(#&&/E39615)#?-!).G%CF-"+036D"<%;1&>,4A"
@r7232
GCAGAAAAATGCATTCCGTGGTTGTCACACCTGGTTTCTCTCANCTGCTTCTGCTTTCGCCACCATCANTTCCAGCTTTTGTGAANGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTNCCATCTCGATACTGGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTG
+
.+?.4CC"?G*2&6C:?&G7C$<1%DE47B1>$3&3&G-?>;$7$&D6-7.,+3G7EEH4H(A6=G2,@4368?HA0#9)=C*>0%>A><-:#G$@283(49H%.&"?'%))!$99980!>@-?)1=#&!:)GA"2$;'"&4G%&9-E,G<"79#A:'&&H&*<$F.)/@>1>!1D@,H1?<@H>'1?:<'53-0<H?>H0505'!@=$3EH"G"B-=%/*:"3D+5)!;!+;F>=-7"*B/+!AC)9%EF,@'&?.#'
@r7233
AGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTNGAGT
+
'3,<',*7;D+,<C-F5./'D!+=<%#.H=#<(.5D*++9+;:71F?704.,-
@r7234
AGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTNGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAANGNGCGTATGGGGATGGGGGCCGGGTGAGGAAAGCTGGCCGATTGACCGGCAGATTATTATGGGCCGCCACGACGAGGAACAGAC
+
?1'0*?2*AH10/A!*76(*$A<3-8,:B2A@1*85H@@:<ECC20:1F:BA!62E28B--:"E7>0B&!0"7-!=A1A30CAB>:(*&B?!3&#"F%$3=#6"A.#",1-:+C<:5AA3E-@0&H&=1#(7D!3#9D50?G+#*D*#(045>%H572;*,E0-:-@=+?
@r7235
GNCNTATTAATACTGAAACTGAGATCAAGCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTCCAGCCATGAACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAGAGGCAGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACACATCGGGTACATGGTTGAAACCATTGCTCACCACCAGGTT
+
#!%)7:,,E5F'9G>5C@4*C$)3*G'691??-,9+//"@#F#85"*)F95F<3)3&<F.G)%1H$>D,?AHB$%D3#"C))-9F-@#EG0FA9?-*".1G>11?*.-G":,/H(?1,5"=G8$"!+';;.H.DF=A9E$$&9+AHBG53?2#8!G'>>.96)7:61BF3H"<.,@4,)4$-A(H<D>$FD-6E?+E7*5/;G),7AA2(F05@E1H*=95H9@A7D2GF8)A6(=92B<39E5-,B75H?,6<7=>"2<-/6?@202F&=&!0+%>%(+*A/3"&.(EC*E/6//=+C"'+("B:<#-9*ABC,F1.4/A6#,3-1!AB2@;<5:H+'A#?9<?'$CA9/!C-=#0C(@./!:?%/78/<(>6+7-G,,A;:(5:1684"
@r7236
TTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATT
+
*G#G9A#EF*E/*,9"A2$2.3@1,=G:/89&F42%3'"4
@r7237
NCCTTACANGAAANTGTNCTANNNCCACAANCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTC
+
)&**"%('*&%%$&#&*(($&&$(('(%*))+)&#'"*&$*+))&+%"*+*'"'"&+%&+++$)&((%(#""+&("+*+'+%%&*$)%'!('&####+&!!#)&"'!+#!&%*"+'&+"(&#'(#'!)*)*!%!")"$
@r7238
ANNANGNTGNNNTNTANNNATNTNNNAGTGNNTNNNTACNCCNNCNCNNNNCNNANNNNGTCCGANTNCNCNGNAGNNGNTANNNTNNCGGTNAANGNGNGNTTT
+
#!##!#$"#$!!$#$#"#!$##"$"""#$"!#"!#!#$$###"!#!"#!!#!"!"!#$#!#"#!"!$$"!#!###!!!!$!#$#"!!""$$#$#!##!$"$"!!$
@r7239
CCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGACAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCAATGCGCCAGCGGCTGATCACCTCCTGCTCCGGATCGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCANCGTTCCGCCGACCAGACTCTGCATCTCTTCCGCCATCCCGGTGACCATACCGTACAGNTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACNGCTCCCCTGAATG
+
,2)C,D-F"+<(B<=43@G.4E82)C!)2?'D+>*B7(&4#$5A-D7,@1(4'0F&'2'48>8!1/">D"AD16D,*9D-7FE)>*5E32!010&&<D"=DF+4-;5:**-&<,#!!74:<<F1!D?"9/-+/316D@(==-)B3=7#9'?F+'(G)>7H-(),7F5(1,0;'7"C':(G+:1GG":B=;/6(@CD*#$(2E?E"?:=-%#''06G6@D6&40$3+5$$,7;@6362?F</D7=HD/146.!';@!2D.(E/-,5:7G/2E8C'D8#*B;">;,/<,D70:H(97E:#,'?"</)H#BF=5+%%(:,,>H&*(E5/?5G
@r7240
GCAGAAGGCTTACGAACNGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTG
+
66#.<'(,+@:'#H3>23%@B*)>+$+?G9A&5<@!);E8(<H/2*4=,!*5A?)DE*?>&8%"
@r7241
AACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCANTCGNAGTAACCATTCAGGAACGCNACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGA
+
1D4C227;:%"6&+%#+H9<CED>7)%7&7G(0?<&BD9C@;"?7H<=D1)9&6;@'#>93"&3H1DBC$H8.H0<E9<&+AG<4H56'*CA:3D)<%&H4F0;:>8?=,*E!.>3"!8<0)+#>8G:.3<&.98'1
@r7242
ANNTNNNGNATNGCAGGNNNTACANNAANCNNNNTCNTNNCNCCCNCGNGTTGANANTNNTNTNTNTTTANGNNCAANGACNNCTNNCNCANNTTNNNNTNNNNNAACGTGAGTNANNTNACANNNNAAGNNTTACC
+
###!$""#"$$##"!"!$#!"##$$!!#!$"!#"#!"$#!##""!!$##$!#""!$$!#!#!!$#!"##!##!"$"#"$#$""#$#$#"""!!$"!"$!"$#"#$$!!"$"#!#"!!"!$#$"!!#!!$!!$#!"$$
@r7243
NTNTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCT
+
&%+!#+#(#&'+*)$(!+%#&'"%&))('+#(*'(##*)&'%!"
@r7244
GCGTGGCTTCTGGTGCCTGGGCCGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTG
+
D$;9A14'0+G61!AC6#6)AH;7?+A#0=;3,!A/9;60<DH1;%2$=!=.3D=6,>9#/F'E
@r7245
CAACTCGTGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGANGCTTTNCGTGCGCGCATAAAATACCTTGATACTGTGCCGGATGAAATCGGTTCGCGACGAGTAGA
+
+)"+$"*%%!!(++)&"!$$!!))+!&+*%)&*$*"&*+%($"%%%#+"+$%"#$%+*#(&+#('$"$$)"!''&"(#)+'%%$(*"&'$++"%%(#')*"#*"('"+!)"
@r7246
NGATNCNTTNCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTC
+
#&'&!%%+%(++"$$%!'**$&%*"*&(*"$"%%*##+))$"&(+)'$%)!
@r7247
NTTGATACATCAACTGCACCTGATATTGAGTGGCCTNCTGTCCCTGTTATGNAGTAATCGTTTTGTGACATGCCGCAGAAACNTTGTANGAAATAANGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTACTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAATTGTTCATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCNTC
+
'@<*/H>:,"11$#G?7:BC>1*@>E;,D5&7AFFC/&;4FEC=*?+,(D&.'(+-?")6);,=A36+0>A=#,B9"%1F90=2@H+:?FF%&!0##3'=,;D9AD%B4F8?#G*@")/5%+?&8(!D4!=8!AF'/G6,BGH+#BB4/8<5(?C0#E$":=6=#%:!2$=!E,D)#&0#H@$H!#=17.'&+H!CAA9F%<$C:G%2)%5(F13+0@16/4.1>7D'%*"94$#@8+>=5)510@1B''@ED%=,>E(==A0;:4:D>0*3'?+0'E8C'@8/.<6B9=G$C),+9(#"89?8
@r7248
CAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGG
+
1)G:B/A5-%/HHD1(::3D"2AB9*7=46FB8'*>-"182C-;2E',++FG$'381'<E.0DF87.C./*F.B
@r7249
GCGTTTACAAANACAGTAATCAACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTG
+
A&2E!3C%D3.*D&=BA-#7,:)(2:E=<&;'D=).C$#,#,'@0-20D3:(."%8,;BA+6=0078G6)?.2:=E)GCDH4G.$/?;EB"7B:;:$!4(03F*%?)!%?-#4$
@r7250
NGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGG
+
%%)@HE@0*H0=9&=!G32$4/0$3!A=C4,0&"F%9@DC
@r7251
GCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTGCTCAGCCTTC
+
G7:"=A;GC?$=3=-115;A*(;,%,A310<(@-7;?,%'>?=/
@r7252
NTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATTCCGCATCAGTAAGCGNATTGGCCCGCATGTTCT
+
#?6FD.430@+=#:03F$>#5;B<&+F:!@188(D=7$C?%3G#'-BB&1#1AH>H,++9BE>7"H%8&1/.>
@r7253
CACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTGGTANTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCANNCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAAGGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATGATGGCATTC
+
6?4A;,A=6/)>3+%A<8='.G?(%/E9;.6<5#FD"+@1%<*G07<2008FF"01A'!(F<$+B%$F1/9?31=A$16=%2A-F*5.(B5F+C<(+(0!FH?$)(7FF'&A&5$-7@:EE,6AG7070:7'F%"",-8+'EE@"38B$AA:;H<?97C%:."9/!0,%&?&6?9F2D<79,4*75D,21F)C&-#'@+675@)!3-*1A$+?E-
@r7254
GGCGGAATATCTGCCGAATGCCGTGTGGACGTAAGCGTGAA
+
:'(+)H!B?F-!<=0639.;5(@;GFAC;6&A-(9C>6/<7
@r7255
GTATTTCCCTCTAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAANACATTCCTAATA
+
?150-5G'#"1#!4#,4%8&+AH3?BE!:A'=!D9)G/;.!A'A6G<<E!H8=183)$*#D#"<)D5'0!8=B/08
@r7256
GGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTT
+
HF,1B3%8*<(;9%8=.2"!2@#:<.FB!1C"0C9<4,7?6A:GC*(@:/C-)54-!F*A*$.5+0'9#G%4,+B'%-F:C%!A?EHF1#$:&B#29.&A*':8(&%%>&%:?.(>4-+"9%62E'D1EG93:/G,/6B+'8%.2EC?=&F+8B>'3@HC<(+<4B#<949$A/<+DD(4C(F.>//D)#0!6)$43*0*%1<CG3</?F$./9G?F)G#97/!"%4/#("H,?7EF=;<5.
@r7257
TATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGNGTACTGGTGCCTTTGCCATTCAGTTCNACACCGCTC
+
$:C1",BC@G</<F!;DA%5H>B'C.9?:+#G2""H!>B!73&C'<:-@3@&1>-;485B;#<EC;$>.,+530;.F1++A*7A0<+?=+-'4A,
@r7258
ATAATGGCGCACATCGTTGCGTCGATTACTGTTTTNGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCNATG
+
6"4,55;G-)H##D<D+-"6>)@G/#H!D8(*C,@8:<.'23"*$>-"0!&H9!'=FGD"'F*:HEC/)=("H=&0/A,E642C19A/A:;()!8$4$3E6(
@r7259
AACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCAAA
+
0?@$->0/8(D3=G6@25A':)'3.&,%<AA"*5).0!?E*:1.$'D/=5F";(2A(H5$B7DC;$@%"7''4E&)#,6E19FB4,F5C$4;+)*:
@r7260
GAACTCGTCNGAATGANTATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAANAAA
+
8G6<#+/:E)<814*A3,E""<.&168C"*@9>;&H&H7H6G>&;=<;EH6)8C+'D
@r7261
AACCCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGAT
+
9DH%>)0+3+4=A=907D96#G-94#(%BGE)69$+?H!@GE1,<G?8=+
@r7262
GCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTT
+
=GA(""&+6C1*=$1>B8=9?"#7=H:#56<$2/D>!%9C;
@r7263
NNNTNANNTNNTNCNGCANNCTGGNNNNANGNNTTNGNNCGNTNNNTNCNTANG
+
#"#$!#"!"#$$$$"$$"#"$!"$!#!"!#!$!!"!!!$$$#"!"##"!"!#$$
@r7264
AACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATAGCAATTTCAAGCGACTTAAATGTGCATATGGTGTTGTGTGTGAGTTCGACTGGAATNATGGAAATGGTCAGGAAGGATGGCCTCCAATGGATGGTAGCGAAGGAATAAGAATTNCCGATATCGATACATCATGAATATTTGATTCAGATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCACTCGAGGCGTTTTTCGTTATGTATAAATAAGGAGCACACCATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTA
+
-/!A1G46.*&>C8!/$2-#*@-G-0(G)7(%G"B(D3H52%G%@B;&F'H$1"8!3/B!9F;:2B*)+&8%B<=;4!/@81H<--D,6>%B@E%A:,/.8?31#$'H2$60'+EB+%<3DE4CH67')AC2;G0'E<;F09(856=@.,C)A0,B"8AA)>@A5";@:-22,<;"FF';6'?!14<%#&02(;1,".#('A$2>&@'*>>'G"*!5E9.$A/1"/,F0-656/+5%@74G(714F(F9&=-+FF,)&,D2;GB;)BEBG4:+5$C&4?2@/)%"6;4@5!;;3E?)(B%<A1=>D@+H),,,=D+G.B0@/F@A1GA73)9$*D.F<5ECEGG6EE2,6.81=#@-C5D.(+8/6$#EBH;84G,=D="32/4;:.3>&F7>6?=)/,5.5?0HC7*4)D,%H%(5C3:'5%..-!8DBHDBB:-+(;H8-#/'0%=A?9!)76
@r7265
AGTCGGACACCATGGCATCACAGTATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGATTTTATTTTGACTGATAGTGACCTG
+
H>*;1B2AEEA*>>C(:D-!'#8F%.%+,0:!C*"+)3#;%ED!"9D+C-')67*=@4</?!:;;')CB=&B10+&9&,."+A0$?GB/*@C";G:=4>
@r7266
NTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACAAAAACGGGNTTTACCTTANCGAAATCGGTACGGATACCGCGAAA
+
!1/!H$;5D*4+63,3%;=%A$$:98G9<3BCD.?/:01#(F3*0?;(52!<>G5,524@A5:,>)@:9A3@6&;A%9".6<':1G?1A*A-5"(@"/DH,*=:9!F/)'/
@r7267
ATCTTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGGCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCANTAAGCAGTGGAGAGCGCGT
+
-%-#><(8;78-$3%5.9>F0@HC;1>@.A%#%3G&.%<</5'F,/.%C9"&??!>3D4G':;DG?=6E923<$'9&5@;"4B";@"37;8D$-*B>04F8>*G%*3=$'/&5>;0%H@;*#/
@r7268
GCAAACTTGTCACGCTAAAGCCAAAACTCAAATCANCAGGCGCCGGACGCTACC
+
!*+%%%")%'&%"'$(%*(&#%*%$))+()&(#!++(*'*#("%($*"'&##$%
@r7269
ACTTATGTTATTACCTATGAANTGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGTCGGGACCACCNTGCGTGGGTTTATAA
+
='5*;5A.+0;E#B.B1$.3*GC?B=>2E9/*)0;'G#565B:EAD3?#),H<*"#AF@,!./-(/A%1B=;H=G#!-658#G@8A:E"&-,@#<>$*
@r7270
GGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCCTGTCGTCGTCAACGA
+
7+6"7:A#F,+-F9(5'4:*CD7:F@0A$H:4D565&D,)?<D?+C5F;E%?<AG!:-,#:);!?%,H;8*@-H9.;
@r7271
ATCGCGGTGACGAGTGCGGTTANAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAAAGTCCGATATCACGAAGGATAAATGC
+
E$(,2.DC!/!6>1%=1?>+-+G;(<FEC%'9/+CD8$?5AAB03'GC;/"3,&;@3)(+C0&"D&9HD@86H,;0(-&47G3,*A
@r7272
AGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGCCCGACTTATGCCCGAGAAG
+
=.=/-;)'-+.96021%>8=<*=25$:$78C3'")1F&#4;=#9'8?:@;H@61@E.$;/&7/D(G>H)E9(4%95D$?9$A=>>3!-'A.<8-85.'$%C,F/6<)70!>
@r7273
CAAATGAAANTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATTATTA
+
(;#=5.,1;54:<9:B=;'C.,BC<EE*;>&),0<C'&;*!+4;AG@1+49$<DE5D826HEB(>03?*1&5-+A4/;B7*)'/+D"&'&')F
@r7274
GTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCT
+
%8ED2E9:?2FB=".$G>'G>H'$=HE-09=A4#$77?<#0-<<B:>1=#)9*(*43;+8F$<):0>5;DA#&0C44'6=?>*@$)8@G
@r7275
ACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTT
+
88%?9#*A&&2#'$@5E$73#=4?4&#E1A8>$'2/4(?8#2;
@r7276
NNTNCAGGGANANNNNANCCGNNCNCCGTGCTCNNNNANTANNGTNGCANGTNNTNACNNCNCCTCACNTCAGTCNNANTACGNANCNNNGNGCGGTNTGNNGNCAGNNNNNNNCNNGGCNNTNNGNCNATCCGNGAANNACNCACNTNNGNNNNCTTGCNNNNNGNANCGNNNNGNTTTTNATGNATGTCNGGNGGNACCCANNGANNAGACNNNANCCTN
+
##$$""$!#$"#!"""#"""##"!#$$#!##$#"$$#"$"#""#!##$$!"#"$!!#!$!!!"$$$#$"#$$"#"$"""#!$$!#"##"#"!!#$!$$!""$$"!#$####!$!$!"#"#$#"$"!!"!"#"#"$$#$"!#!"$$#!!"!$$!$$$!#$"#$!!""#$#!$$!##$!$!"#""$"$"$#"#!$"""#!#$##$###!"!###$!""$"$##!
@r7277
AGTGGATCCANTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGAAGGGGTACACGAG
+
.-&$A+:,B96-#(*+":G?@45**GC9?==(+8F2G+F<>?8('*2&9G%3+H$&$><#4"9'@&:1#8*(3-"4=<
@r7278
TTAATGTTTGAATGTGATAACCTTCCTTTAAAAANGTCGTTTCTGCAAGATTGGCTGTNTAGTCAACTNACTCTTCTGTCGAAGTGATATTTTTAGNCTTATCTACCAGTTTTANACGCTCTTTAATATCTTCAGGAATTATTTTATTGNCTATTGTATCATGC
+
*+*<?(C$./'..H!:6<FD0-&F&6(&<<.2&<EG,=A1#?F"A7+&F+$5'!&59,3)5DD$(CEEC1AB0(:"+1(B743@0#.(/<7*1@,)*E+B)-01B>"D3,?+3(0A1/3(25(<?$30<1<;%:;4::;!0&2$2B%/8HCD:@!-3+/!D24<
@r7279
ACTTTCATTTGTAATAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAA
+
A;B>'DB1,C2=C7;D3/)4,)#>1<#,.A%5(7>#&2'*0'?<E7@E;="*D
@r7280
CAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGNACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACA
+
8E!D(B5C'6<326F?3>?C=?@42,?(":(?:*@G&/@B3#117B=)513'9291B'7>,(.F7-?!=DB%G/6&(;F%AD(*2:(3C9,A05=/3'!F9)BB2>.$&C4>D.4@1;::+!)-49-H<A@*+0#BED*EA;;5B6!
@r7281
CCAGCCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCANGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACNACGATTGGTTTGGTTGGGTCTGGAAGGATTTGCT
+
/)F#!)5&%8:;3(()@4D87$-/#4/H"#66+0:&,;'.B,051H511)BH,5<*>6)/@#@++:,4.<1A=<4=171<+')HE5=HF!A'EB@F'0:>$F'A?11!7B!+0(0D2"'#15>()HD)$*%GCEG6.A
@r7282
NGCGTTCCGGCGATGAAGCCGGGGCATTGCAGGCGGCGAACGAGGCCGCAACGA
+
*9B&1H8A:8<;F6$226")G#83).0.1>&%BE.:#&"A(9?E586C6>A8,'
@r7283
CCGGAGNTGGACGATGAAGACCTTCCGCTGAGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCA
+
4138:6;7'0::E+.*4$34&5.";2-287:B=%;+(E08;4:.A;5D+'&%:G!2=GB-;"9HAG,*&92$0)8:$)B?B3-120=#>$0%2;&"#6;E<4&G-?D94E>CGF?H/6,?A2=$3:@
@r7284
TTCTTTGCCTCACGATCGCCCCCAAAACACATAACCAATTGTATTTATT
+
CD3,!;!1#'&B%)42A?1.;>#++8$?"%.:<6)F/C>=%@B&5@-(9
@r7285
GCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCCGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTG
+
3/$0+>C*A,$>(G$<EG*GD@ED384C9(=.12$C!7;H</C'&!F-E#B5!032;;+>?2E"-!@#026;>C&,0.?GF->%'92E+>"1#??/6;/!&)14%#D+"A&)H38FC4.!8C%$/'*.;$;##!F1(!C5)"F.G7%3:
@r7286
TAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCC
+
=@E@9@)7AA0B:5=,CA166FG41"/;''B@;C#EFA*@:53=CH.C?!F48
@r7287
GGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGNCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTNGTAATGGGTAA
+
(;>H!'"4F.A?1$HD)>,D';0,CF05.-,.C17:-.7=<HE4*;%%<>BB=):$'8<</8428G07&'C!<E>.>&)0$C:"9$H;%)E
@r7288
TATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGG
+
6A*85D.6HA*=<F2399>'53)E=9B4@7-59<"F:07?).)7<2
@r7289
TANAGAGGATATTTACTGGACTGAATTNGTTGCTAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCA
+
'''"+%##&&$*%*)!(+#%#'!'"'"!$)(%()*%)!$*+#!(*$!&)#+!&#$#++!"$"**#*&"'%+*$$)'*")(+$"'%()**"!!"$%"+!")#*+(#*%)$!((#&#&*(&!+&*)*)+#()#(&
@r7290
GTGATTTCTCTGCCTTCGCGANTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATNCGGTAACACAGATCGGATGATTACGGTCCTTG
+
+%)'$%(#$)!"%!$%&$('"&%#'')!')+$&!#&'!"%(+)*$$+&$'"))!#!+!%)%'+%!%$(*$!&#'"%(!*#**#*"+''&&
@r7291
NGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGT
+
$(*+(++")+#$+%%**(&#'$+'$"%*+$)"!&*')*'")(+*(++!")#$))'*%!!&*$"#"%)"(#&!")*+'*$#+%"+&+#%'
@r7292
CACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGANACTCAATCAACAACTGTTTCAGCCACTGCTNCGC
+
'.,!,H")A0F+=A/!-<C98G137)17=!;&-&D%0B72#,=;D70A'B'=F,((#-B"FD,DH.4"86;>&?-'0/CF4$&/
@r7293
CATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCANCCT
+
5/:,F">C09(<A:8:$4;&4-:6((01DFD'):"!+=)0-"7##,2B-2/6G-$2/&.?'+#E&"
@r7294
ACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGG
+
:9:*7:)7(#";-B(-998C36B0>$$%7(F*46G"!H!--;&'0
@r7295
ATTCCTACGAGCAGATGGNTGGAATGACTATTCCTTTGTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGC
+
1H*+>$;$D''H5D)87==@>&@**4@5EH2>#(/D.A7!204>-+6(20D*/5:F>-42>-0+>%+:7E/%/H*=&&>3D!#6+
@r7296
GTTTTTTTGATGACCCTGAAAATATCAGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTGATGNGGTGCGGCAGCTGCGGCGTGG
+
-&3;'&E0!A7/G%G'9F1</*5CE('0GG*H?-$&+3D723D*1;;@4."$$B>0EH+?8;<*/F83953CA%4)1F>3H6#-!0:%$DBC',?H@@'0EB!0>DB,H'H.
@r7297
GTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGGAGGG
+
G,$"02381%8?2E&?;A.B$#7(54-(%-HC97+;(."F2,6F&%"-8,E+'#$6.E)+#6$
@r7298
CTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAANCAGCGCCCGNCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGC
+
?EF)699<E?C3#7=@&%8%90E:?)G;F>=G7@9.,2B4-*(,G9-.0-/7--)?"2>=F,2>C=7+@A!>,,80:.;D20AC4B0FH70G98)/*-)-:1EAC82.7(;6-H6:1'<<
@r7299
TGCTGANNCCCAGACGTAACAGCACCACGGTGGTGGTGAACACGGTGGGCTCAGAGAATCCGGATGAAGCCGGGCGTTACAGCATGGAT
+
!#)#)(('#+%#%#&++'!'!%+#'$$%"++*()"%((#*#!)+#)*#+#'+&'%+&**"+&$'#&!+&*&!*'))*('%*$))+'"#'
@r7300
NTGNGATTGCAATCCCTCAATTTGAGGGATGTTTTATCCCT
+
'"&"%$*!(++++*$%"#*$)*%*&"+&%!(#"&#'&!(+"
@r7301
TGGCTANTGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTNGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATCAACCCGGAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAAGGATATTCAGACGCNAATGCCTGTTCTGAAGCCATTTATNGATATGGTAAAGAAATAT
+
%1D>;4C5:%*6G$-/$A79<.H;#B"B1B2ECC))7=G3+1.6#E9B5>65F946@G6H"='1#@=<):B$02%529'?7$(4B$E@<%$7(807>DHC(=4F3@E%">1(H/8=G?D&2!E!";$C:")/4*B26G&>F7,$42D4:C!BH7)(39>;?"4(*-;)*!>?-@(6?2%7$#36!G'%,C,3$(%/-<&@&9!8'#H>1,2C$%A;4%5"8"*>45@8,AF3)1)#HC/#77(/C4/.?B5E
@r7302
ACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCNGTAAATCC
+
81-)F)D?"9C$!*?D#:G'=<ED+B02%:.5/G"(G>4<>$&',$.3%*":6GC)51+79<
@r7303
TATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTNTAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGANAATAGTTAGAGAAAACGAAGAA
+
&*)&+!*$'&#*!"+)%!'&$&&)$%)%&*+!!#*'))*$#!'"&&#&###!%#()#(*'(*'+)("!(*$("#&&&&($)%$#&)(*("#((++(!$%!(+%'#"*%*$&(++(#%#(&'!&!"(+$(*%)%%!&'*""!*()"'$%)+%(*#"%%"
@r7304
TCGGGCCGAGCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTNCAGATAGAGNCACTGATGAGGGGAACCACCAAAGACGATGTTATGCATATGCATTTCATCGGCCGNAC
+
D$4<)D7*@&&-5+3"@#&$%+0/6,%:DG3!(!F!C.)#40.A6?009DB.543.A3""$D$G!#A$+0&=HHH7BDA&3:2;,<E288(?+8-8F019..85'H1-5>E#E/.-&F.6@67H151=$/0-0@829&BG-3
@r7305
AGGNAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGGCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCA
+
8()G?=;>C$52@)4;,H16E*./$'3C%E4H+#4"#**70.HB:.E=&7$(4';%&&E.65>5%=53D"&EH6!<D:&%#1=H&"8&-8+!/$)!)"@46,+)4#='2C.C.$E&0-50A;,6F(&F7BH))974A/=39#;B,H7B%D1GB24&DA:0F@H
@r7306
NGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGTATAGATTTAGAGTCGGCATACAAATATTCCATGAAGGTTTATAAGTCTAATGAAGACAAATCCCCATTCTGCAATGTGCGAGAAATGACTGATACCGTGCAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGNGATTTATTTTATCNGAACTCGCTACGGCNGGTTTTGTTTTATGGAGATGATAAATGCA
+
"3*1&C!(#3:78D!F8D(%9ECGE0-!30:50+@,6":!%B!H3$,#*.B&?1/&:*5:%$&?D:GD.4C&C<42E)E1(.9@;;(7FD/F7A8'G)BE<B+H@FA>8GG!,9=,6(3"!)E@-"#,6G:G!H;<#C.FB&B'>E9G7)61!/A;0='#8E3$/(82F@?4(1@45.1(6CC@!%#(5!.D2*34@H8*0G"'"D4@.H><F:#&>C-'.,";:=0*%@1D!,&8F?6>CA%F9:*5:>%HA%:&5?$C=/)+2,A-C<':6<CGA!*A?,0*=0G03GB"BG.H=*)4)&8%68D(>+"'>*)H$E?5>E9,<1-'*'8.E:B34$
@r7307
TAAGAAGATAGCAGTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACGACTTCCCCACACCCAGCATGCATACCTTNCCGCCATAACTGTAGTGAATGTCTGTTATGAGCG
+
08,#'"8(4=?H(/<"</?+B,$10B%:1<7+D,*7!0F5:,.'),@?*!A89!F"A9,&-*(B6.:@85,C!++G8>%/&<5+G',+G6&%*,F".0,4,9)G-)C:#,.38C9
@r7308
AGTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCA
+
)F@%>"<:>.+(DG-5"5A)'18(/+9D74?>!7@2-D>%.27-).*&
@r7309
TTTTTATGATAAACAATNCCATCCAGTTGATTTAATNAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTC
+
"$*++#(''!!'$)!))$!#!!%!!+#$+&!+$"#%+'$)%*(%%!(!$&"$&%+($&'!"+)+)"!&$!$'*(+"(%'#&(+)%&+&"+'!"%)%$&#*'+%"*'%!&*$)"**!%&!'"'"$
@r7310
NGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGNGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCTG
+
$)2D100,"+7C#%%#/A.C$EH#H7,C.@(&(#B2@*5/0<B19#:5;0(%''B'3$&,B?&(;!:<@4GF)1>:/+:G%)H1&3A3+7,F90$'D"7=E:64$105E4-2HF$&GFG@-6*/H&"
@r7311
TTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTNCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATG
+
GD,?"=*=E,;-?89#?80$'9$-1758G5=0GC10*'2GF*.G(<C($7,,H:>)$#G/2;1)(:!2/;'!H-9?/7A21<2<)=7GDD6175F&'C.1531+=?&26-4?:-C$%&G1#'7&"9;1'*E!."58CD>$B+9!A'%+G'71/%>)=&>C=)AH*G6*(EA-8&7*4/G&$<,+74?2"-@&;H5:H>&+,7820.B!>%<>6#><<0&8&B#:70%1"0G!<61?B*'*E1G<;#@,!5.C'G=$>&=/#/$@>4E9G4C%'121,'*/#FG,A0113E1/,B.?@F+@E1$A3G9H@A8*&4-9:#-8FF22$3:(1D.<D4-G58>5CH
@r7312
CATGTGCTATCTGCGCCCCTATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTNTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCA
+
#+&*%++'$&(#"(&&$)!&+%**'$"()$*%&$&#**!+()#+"'!)#+#$'$&&+'&(!&$#!&'!&"#()!$#&%!)%*'#"#+%#%$##&('%!&'(%("(%"'#('%%"&#&%("*('*)'%$*)#$"+%!"$")%%$$!%!("(+!((*+"!*$"$)'""!)$&(*%#*%#'%$)+"*%'*)#%+&+$"!)(##'))'&"""+(
@r7313
TGNTGATAGATTTAACGNATGAGCACAAAAAAGAAACCATCAACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCNATTTATGAAAAAAAGA
+
#*#(&+'"%+#!!%*%%'''"$"(")%')"("'#&$#!'!&$!&#'#*))#&%$+%+$*()+*$&(*')&&*#''%"#&&*(+!!'(*''$)'!"**
@r7314
NTAAATTAGAAAAGCGTTATGAAAANAATCTCCGAGATAAAAACAAACCCGCNAGAACATATTACGATGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAAAAAATATAGATCANTTTCTTCCTATTGCAC
+
%,.'&:9C.+24+=(893A=9%@:'H--@H?98428G7/H)(5='204?EF3="D6$/,BH%,2D1C2=G1%+F=#2@,0G34"@F,.A4,,)89!./'B7:,$<1?9@4-27E4./G=?)DH=<9D:.5@638A3,*E"2+173FFA##250-/(
@r7315
CATATTTCTTTANCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGG
+
+"*$((%*+)$$%#$""&&)"*#*$#"")'+*%'%(&"$!(%)'*'#+)($!"(!(&'+&&(+"+%%)+&"&&'++"*#*+#'*#$!$
@r7316
CAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTGTACGGAC
+
$CG%?3B&(EA,D$6'6>CG><%*/?9-&&;A<6>1$%=4"1C:"/D=8>/H$2B64&4*$0492+01.1(11&HGA"
@r7317
CCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCAAGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGCTCCGAGACGGTGCTGNGTACGGAAGTGAAATATGACACGCCGATCNCCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTA
+
FG+#$$,$+F48,15308;@04@#B4@.+0".B4/.30+)4;!:<!7<:?97@"):*!2/@<6-/65-7;.3$9)'>A?+&5)"@FGHC6%-+0/#:2&)>(:#"2F+6#-7.C85"&'%1%B3%/*#>C%@:%&F:A$5E)FB0'95&E"?$C8&$?1!0:D3"1D.123)71.)AC),0F5.AF&45.GB.
@r7318
GTTAATTCTATGCCCAGCACGAACATTNATGCTTTTATCGGGCGGAATGGGTGTGGTAAAACAACAATTTTG
+
,3='.;#?*B7)05(80H-A,DF6=8=.>+:)"5@D8?AB?(/$/!5@>2<#2+5FE<<,C%"!E(/-340.
@r7319
AGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATC
+
C.3'G83-E+.>48@:(6%%63"47#19)>H!-"?@A7,):&:==5!,=)(>>:?'=$D$;6'(8'#9!!>"=#$:%>',#=@68+.132AE"6>?(E%F#F)"$HB(//25"*6;9B5C3,=0+7-!E!&B+;#*;5*+#%D*
@r7320
NTNTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATAAGTAAATAGCTCTCCGCCTACAATGACGTCATAACCATGATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGGTTATTGATTTCTAC
+
"&#$+&!+$&''+')+**!!&'"'&+')"(#%(("!**%("('("(&#***%%+$'*%("!)&'#"*##!'#$*)#!$%&"++($)**"(&+($&#!(#%!!&*"!!(!#+$)*(#)"(&($*)+$*#(+##++!(%$#%'%)*&(*$'#"*%*%)#*!+$)&+!*&%)%!')!%%!(
@r7321
NNATTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACAAATTCTCTCA
+
"#("+"$''#)!)("!#&$+$)#))"))*#$*)&$%#*!)!'#"&'(*%!%))%+('%%%)%)!$!"'!!)#&"*"))(*(*&&"#*#%)!**%&&&#))*('&"&%("'"%)!
@r7322
TCAGCAGTGCAACCAACAGCACGTCTGAAACGCTTGCTGCAACCCCAAAGGCGGTTAAGGTGGTAATGGAT
+
&0'7)%H.AH;28*.4@7?#.DA<)H'/F("@D*482H7GHHF'43-*'1?",<9>304<<+4&:'9.-*@
@r7323
CNCNTCTAAATATGTNNNNNTNAAAATCGGNATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAAATAATGT
+
%&$""&%')$**)('%($%$)"#%&#(##&&&(*+*+*$)##*(#&)(!!))(#!*(%"*'$*)#'(#")#"&*+%+!""#)$*($+!)*
@r7324
NGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCAGCTCTGCAATATATTTTTTCA
+
!F<<H)'&!C+0E"AC;2&3?>4:+*./%$<"G6+EE0F=$=A.:=+1(0E%F/4#!<%8$
@r7325
CCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTNGAGCGGCGC
+
+&?1)9&>;.74&*,1<%,($9F:B21(@.3/?)C$>7+:+"):/E7B$5.04;!89EH45=?%-7D+$35&6;$"8<EC,
@r7326
GTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAA
+
G$!#1<=@!)%;%%/<3H)9>@>#,417+@H%9>%81?(8!<06*
@r7327
GTGTGACCGCACTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCT
+
/7.99$7:%C,:B4E@1'7/%-H35<D6!<$B!.,/A:#D$1D0;?$7.(,+!B,/.+''E08&C3AF6.4H1E5!@F.H&+86?--*E62F-%/>H-1496C6.')&3H9B!%?B-&3:ED
@r7328
CGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCTGCTGCGTGTGGATGAGGCCATCAATAAAACCTATACCCGCCGGAATGGTGCAGAAATGTCGATATCCCGTANCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTNTGAACGCACGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGG
+
,'GBA,2,8BD78!>0G<'!.&/-0F"C!G72F"*A(F)$?G>5=7-&4C%8*$4)*"8F.G;<%>=EB?.#3"@;6%H1=-$=F;;,A)H,;8!G4C,,,3&)68G?%%F'HCF,0)+=357)#A+A)6B*&%=(H.!"!@?8,/$!67"@#:84G@9$A%$,FF#<4';66'.E;::%4>=7)F'60)2)0&3!B)+E*$CC/854&.A%60B
@r7329
AAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGG
+
=1F%@B$AC(@3@<+7E1A(.&;>D=#G43D"G87&D*2(2'?!?CA4)';#:<:@,)%D#B.5"B'B&C#*+&&:'A+0'GB6!@A+.>7()A);&
@r7330
CTGGAGTGGAAAGCGAGATGGNGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGTGGCAGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAA
+
904>G-D'+:6G4),'5=6<1!1<+-)$*;0D(G"E>>%59;.CCFA?>39A8"60F"<+@#$C8>A?95A".H1#+%!0@AA>'A)5#0'+)=;9),>$>@
@r7331
NCGGCAGNCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCA
+
"4E*)!E>2611%'CC)75GE78,E,(9@"A0987?->#=C.1;",:%G*!#D+A!!>040<*D;GC4?%-*?9"3HA=7'D:C&0!7B"-D;A9<,:==7$37AA.2#F)D0E@'
@r7332
GCGGCTTGGTGTTCTTTCAGTTCTTCANTTCGAATATTGGTTACGTCTG
+
/E":"A;<>FC"%D$7"C+/5!?#E(<DB40&#=9>@HC=#CAF6*EF9
@r7333
ANTNCATNNTNNTNCAGGGTGTTTATGCCTACTTTATAGAGCATAAGCAGCGTAACACTCTTNTCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGANAACCCACGTTGAGCCGACTATTCGTGATATTCCGTCG
+
())")*#!!*###!(!(#'+'%+(&%+!&)")'+"'%%%%*#"&*!")*#*)*"*'&$+)%)&!'$*&+)+$&$(#(*&*'&#++%#"+'("'!%#()'*$&)($%!"(##%%%()*&***%#*('##!'%$"''%%$(!
@r7334
TATAAATAACAGAATAAACACTGCACTGTGTATTCATTCCAACGAGTGAATACACGGAGCAA
+
73D$>4>"./"8/5(.*9A(:7?GAA'4<F7A:97&,;/392!*C/*.EFH!@(>(*+$#&1
@r7335
CNGGAGTTCTGCCTGAAGCGTCAGCANGGCAGCATGAGCACTGTCTTCCT
+
"#&%%+(#*%(%!(($)"($#!"#()$+#'&)$')#(*&)'*""&)%$%#
@r7336
CTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGAT
+
E!(7C&0932=$06-".$A>(GHHBE5GD:<=@*FE0B$$>3'23:%E&)'
@r7337
NCTGCACGNACAGGCCGGTATATGCCGACACCTTCTGCGCAAATATCTGGCGGCTTGCGTCC
+
"70+9452083)<8/(G2".246;D79E8*8B9@*;5>5@/>?7(/5(2G*<!$!7%?B=F!
@r7338
GCAAACTTATCGCTTATCTGCTTCTCATAGAGTCTTGCAGA
+
88!0C@78"@@7+A-=GE5)#*G;,!2F+@C70#)G#5="C
@r7339
TGGGCTTTTTTGTGGGGAGAATATGGCAGTACAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAG
+
A=C/8EAG!&C9F*1E92"6:E4'EFFG-B39G1?F:283:>CB;'3B?=!-,1CA9B%$@<><$?C8"%$/FFA6GH=5BB$=BC?GF*82:)&+*)H"-2
@r7340
CGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTNCGCTGGAGAAACAGGGTGTGGAAAT
+
B0=F2D.>2?(A-@8!=:,&76"!=#+$BB:F%62/C2?37,@$*-A4*!:7=-4;:C=/3'F9D"H+<165B96GEF2..)%5B$62A$==8,'*G8D.#;'><
@r7341
GGTATGCGGTAAAACCGCACTCAGACGGCCTTGATAGTCATATCATCTGA
+
E27&$$36/'HC,(=>066&6.#3?B308.E$&.80'9&5G"*AB9A1A2
@r7342
ATCGGCCTCAGCATGGAGGACACGGACAAANTGAACCAGTTTCTGGTTGCCGCCAATCGTATCG
+
5>)??=D(3(%E(9D$,E8*>(4$)*4?/1>@=26"4%C3BF=@,/.-H;&'C+5EG*82<$>1
@r7343
CACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTA
+
$2"7GFA".$1.H'B@>9*<487<>/<9A:!9D%6$%!CC)'@3
@r7344
GTGATTAAGAAACAGGNGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGA
+
,7";.$.#AG!'+4476%;E49$F4&$2!D6()@@"4#>"$F"-*/5>6$.("AG>>G5%$0!A@G88-F2<00AC;8$72==D:4A>92
@r7345
TAGATGGTCATCTTTTAACTCCATATACCGCCAATACCCGTTTCATCGCGGCNCTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCNTTTTAGCNNCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGNCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCNGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTTGATTTCNGCGATCTTCGCCAGAGCNTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATCGCCTCACNACGGTTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTTACGGCGTAATNCCGCATCAGTAAGCGCATTGG
+
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
@r7346
TGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGGCGCGGGCAATG
+
E>4@H<<3G08E2CC3.)#!5'@46*1792=$3?%+(C$2#2H7*G-6':)>0*9=:("9=$'G'F8"(
@r7347
GCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTGAAGAAATGTTTCCTGTAATGGAAGATG
+
8!'*;1H+E,*CH.--!8F6FCGFDG0G04&5&>+&?3#++.)'='B;3"->'4#.6E+$)&5""C"@?
@r7348
NAAAACTGCAACTCAATTACTGCAATGCCCTCNTAATTAAGTGAATNTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGANGTTCA
+
#DC(1E(F8'*'#0G6*F?H:@?$D-)4?"@)950>2$/+.!$)%A?BG.8E#:)EH/=;%.F#/1:5$)77#)(#=>=+;B/'H7.A0
@r7349
AACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGT
+
+$(*#('!&((*%$&*#&**(%)))%+(#!)&&+$()&!(('&
@r7350
NGNTNCCACNTTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAATCGCCNACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCGTATC
+
"*'$!&'"$'+$%"$"$)'')%($!')!!$"')&$***&&*')"#!!$*()++&*'#)&&"#"$+"')!+)(&&#!$"')$#'!'&!+$'#+"&&"&$)#&'!#)$+(*'(#%+&(&!&#*!#!"%#($$!#%''&$**&%!&#))#!#+"&!'+#!!()&&+&((*!$%!(
@r7351
CNGTCNNCNTGCNGCTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAG
+
'#*#)#"*$)'!%+!&%%+$"!!%)%&!'"$+!%*!%)*+"*&"&!+$$&#'
@r7352
NCNNTGGATGATATGGGCGCAGATACCACATGCAGACGTNANCA
+
#("$+'%!%$+(+%&#((#)!+&($"""&%)')%%'+&(%$+&!
@r7353
TTTGCATACATTCAATCAATTGTTATCTAAGGAAATACTTACATATGGTTCGTGCAAACAAANGCAACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATCGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGACGAGGGACTGGATGCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATNGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGCCANGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGNGGCAACCGAGCGT
+
))0#D;$2"$-<8&2B2',&!4":(F/69-=*(?!8;$=6;'B2#%F-!1>?4C3+/<824(3$EG3@F)#),G=B!26?B/)(21<BA5<9"4$E:%(7-C*#GD>F"$3%(@&B@G42@H.<E1.?//9>C/"80?;$=/E++8(-$G371G:8%>+G%(1(),A)!&?80(6%!+B<7(D@4)FD%A,.''$5*7HD+,;<H9#GFH4-C?2)A9F>H/"*D+'./&7.8?*@,/8/D3;!>3*%.1.0,*@F/5D,+0+'*25$F=)'G27B)-=$9$6#"'?>@36:+B<4&1"&%/*?'"@=!2<
@r7354
GGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGC
+
9;E=7)9.$6)5';*2:E#,.$(,*:H"6=B?8@@D.(<!@%&C@4@)*G5B.H9<4=C#(.)<2C%=*7E@7354=2%7>*B(9?8+C/@"2F6&5A19
@r7355
ACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACG
+
9#13G/"")B/A+#/;=25>0#;@G#HB-?4H61)/=$-87-4)?")'%DA&"'/+#)"+"4#5??262'5<54$2C2"A%"CGH$64@8);3A/@5H(#=C/:)(A0-@'D@#GD1:/6*;+F)7F)@B74&H#-<?6,B*D?6:1-G7(A9!!+/C2E.FH-H8"0(9::+H<@-!AD>:)&E",F>/E3?<%<>1G75-BD/6.:9<(/A4:@>AC3=;0/B*;1C0G5'%4+/10$9>,"E$(?&)@?*,""1!%)1%<;6#!.*2@41
@r7356
TNNCNANNCGGNAGNATCCGNTTNNANAANTNNANNANATNGGNNTN
+
$!#"!$$#$!#"$"""!"!"$$$"$!!$""!#!$!#""$#!$$""!#
@r7357
TGTCATACACCGCCTTCAGAGCAGNCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTTAATCACCACATGGTTATTCTGCTCAAACGTCCCGGACGCCTGCGACCGGCTGTCTGCCATGCTGCCCGGTGTNCCGACATAACCGCCGGTGGCA
+
>)#HC?$'.H(?&728>G>A#@'>91,3-'%5HBG69G+3.9(5'+,FBG&'F%,9C-!=F60#1.,E4?/#=;4!?-!!1;C@$E<(-!<%H+C.)H::B%>2#:G$;(@=9E/=%;BCHC7259.&*"D4?D>D>7&7,@!HE:>93D:G
@r7358
CAGCCAGACCCGGACGCTGACCCTCGACCGTGAAATCGCGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTANAAGTAAGCCGTGTTCCTGACGGTGTTGCTGANTACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAG
+
(=?E00/C75*/+%+?;4.&.B>14#95H#6C9?@E&D%F9/.#=5D+C:?GG@@B/%F5%(0;*C9?*6&/EHC"*CF@(E;3@9GDB46C0,<#C#72->42=2+!?5)A,3(=',@2&:0"374/=#C<,(@H>C>./&"G*8-&">:1C6D-=B7174'1=F6H4&E?>H/B@H;(1=>9E4FGA-"2+B@/.*#-BD-(1C,-
@r7359
AAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCG
+
B=):2H70!'*-FA>3#(+$*A;6A.!-22(,5++AB?#GG11+;7/4A,*8,*?4.;$-?EC<C#@"8>07>D34>32;);3,/8@(&8$;((=!A*/
@r7360
GGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGATACATGGTAAGTCGCGGTCACTTTCTCTGATGAAGGCGTTTA
+
6C?:!HH>>'!926H<,G*7G=@.38=$48#F=(<D@"%F/7;,4/G?.4<9-$=0#A**>688<.HHEC*7+%C43&*/411*'=*D%:
@r7361
AGCCGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGG
+
H8.#1HD#.B++,+6@$A8@!=!>?$)0:F%A?6$/6()C./(03+%,FG;
@r7362
TCCTCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTANGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCNGCGAAACCCGATCTACCCAGAAATTTTCCTCACCG
+
75<A%'CFB%(*!..$'3)>18/:;?4$33'<4A?#4*99'&E27A:5&')ED?>2%4H@:55&.(H82GC798/1&43>E)'F0<#G$#-7+:$0>8G#!'$!381@*+="")
@r7363
ACAGCAACCATTACAGGAAGTTTATCCCCAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAANACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTTCAGCCGTGAGTGCCGGTGCACATGCGCATACAGTTNGTATTGGTG
+
+1*/):7B>-2F/!7478!@9D66!$7E;;)$+7(H175(F%!5%H;0&B,.")A686A-'#D8+"7'C:<=B2+8091F,#<4D&H4)08-2H:6*!86@,;F7B+2)9C@:$(-1@!+304C(%&E7-!36)%0"1%9#E;B;()4-F0"H63--
@r7364
ATTGCCCGTCAGGCTAATTCTGAAATCAAAAAAAGCCAGACAGCAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGCGAACTGAAGAAGCACCGCGAAACGGTAACGCTGATNGGATTCACACCGACTCATTTAAGCCTGGCAANCGGCATGTTAAACGGCGTCTTTAAGGAACG
+
6!(4<@C+HF,H7A)&(;%'2*B0/?<8.5-@!H*3(2406H)4'!7AF#7H03-F7,,(E;;)*1GF*CE&C<$%F@;<>:&G;*B"G$E89,!'069<F$=;(A?3*04%'3.=>)+8!0#E+@$147E84)$$4H/3B>:H7<C(*3G!(98)D%2*+.!7C1'AB1!$9#EB97!B
@r7365
GCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAAGCATTCAGAG
+
?1)4B.=A=G:91)@.7$:4+@:8+"B8214(E;0!%4/)40+D81,3*!6/C6@"C?D??+)>E2<@9?D2CA>=/#<992<
@r7366
TNACTTNGCNNCTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTTACCTACGACAGTACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACANAGGTTAAATTAGAAAAGCGTT
+
#'"'*'&#(#"+)+%$+*&"*%#$)!)'**''))*#!%+"&))*)%&+#)&!*''"%(!(($'!**!(#$'+")!+%'(%%!&"'%##(%"$(""*&#*('+))'$"*(*)+#+!$$)%%"'$)+($'+)$!"$((+!##%*%)#(
@r7367
NACGCTCCTANNTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGNCCCCGTCAGGCTGACATCACGGTTCAGTTGTTCACCCAGTGAGCGGAGACGNGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGNTTACGCCAGTTGTACGGACACGAACTCATCA
+
#'%&(!&')!'+'%'('#*&*&+(+'*&"+"$'!$$#')")#"+#!(%$)$#+(##*#+%$!$)$()!(!)++"+"))$&)"'%!*"+&'($###+"''''$+%$$%#)$$(&#((+%%&)')%&!+('#*'"#!%)!')$&*#&'+$&$#+")((*$&"*%"'!$&%#%%$($!'&&!(!**%'#)!&(%%'#('
@r7368
TATGTAAACACCAGGCATGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAA
+
(2?*?;@">F-<09'=">"1C,D90#)1?4HD.,G-7C<2=-3<G&FA5D?<%D@&@-H
@r7369
CTGCGCCTCTTCGGTATATTTCAGCCGGGACGCTTCGGTATC
+
?H>HF"82$.7>0G:80"!G0"B24<5.,.:%B:B6$C-./3
@r7370
CACAACGNGCGAATTAACCCATCGTTGAGTCNAATNTACCCAATTTTATTCAATAAGTCAAT
+
E",%CD':-B59?=A-1:1;,#8<!A-)(#D/4=;-,6/2!.2&'G&$)'3")F:B#0<:!$
@r7371
GCAGCGACATGGTTTGTTGTTATATGGNCTTCAGCTATTGCCTCTCGG
+
@5E1E@()7,-.5<=7<@-09>?4BB441AH"C'+%H*0DA)D*&<B&
@r7372
TATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCG
+
A,.4<0+G?8!6=%>%)7=-)./B'"DC;/E@;=,#>-6<:&671G2&)$'4@?7)5$BH!C!&?@=)F&D&3%6=H<"&0
@r7373
NTTGNGGCTTGTTGGGCATGTTTAATCCAGTNACTGCGGG
+
')$$!+++'"#$+%*'%)"**$"$%!$%#*"'#*)%)"+*
@r7374
TCCGAACAGGACGATATTGTAAATTCACTTAATTACGAGGGCATTGCAGTAATTGAGTTGCAGT
+
26#:?36*C@>D>8,5B2"-@85;4;-&!-$=-./#(50E0'D@7?FA1&<1H,$?3>>931DD
@r7375
GCTNGTTNTNTNAACGAGATTGCTACTTAGTCCGGCGAAGTCGNGAAG
+
$'#")$'$#&!!%#'&&+&&'&"!$'*+($+$*'%#)""%!'!&%"*&
@r7376
CGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATC
+
-G0>H#GE+6DE29-783.-0G56G<G>E+'F-<--7G$C;
@r7377
GTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTAC
+
<:68,=&:$-=B./+"?>5$'E0?#D!*5EE(5+(89@'FAF:!2B98?D<+?0'(A/+0;)-,>"H/))%$2;F#
@r7378
TTACGTCTGCATGTGCTATCTGCGCCCATATCATCCAGTGGTCGTAGCAGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAA
+
D>>60)4+"%H4@AG6:4>5-'A:90@A4<09:=>,1/*?2&+:685E>?C$05'C+!3+H:(.6@03=5?"AA*G8$<"8F.*C(*;A0"!&*01-G5$A3)GB">=1>1?47=H-B@C-9/4E9E-?F%15,*"(C($!".&1-HG7C)"$E#E='%-2*6;0
@r7379
GTCCGCCAGATTCTGCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCA
+
3;'.,)57>F-':(/C:!-22G,FF/1@<--@*B!327$+G70$+F-4:$5=E,=8F<8
@r7380
GGNNNGCAGNNANGTCCGAGACGAATGCCAGGTCATCTGAAACAGCAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGGAGTGCGTCAACGGCATACACGAAGGCGACAGAGGCTGCGGGAAG
+
(&#$%)'*$"$&!)+$'##"&)(*&+*(""!"'&**!(#*#*%)#+))$+%!%'#(")"*&#"')*+++!+++%)&+%$(*"+&&*)&+""''!&%%&$$&#$(%%+)*$&+%+!$"$#"#%&"$%$$#%$)'*%!&")""+
@r7381
TATTGAACAATAAATAGATACAACTCACTAAACATAGCAATTCAGATNTCTCACCTACCAAA
+
?H'H"?5*G949,C7H&'?G2$3)2C#>53,A!@>';;#B1+-7-9@1C5C43>!E2G$%B>
@r7382
NCGTCTCTTTGTCGCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGNGCAGGNAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCT
+
"(&*$+(&&$+*+"**!&(&*(!*)!(%"&'')"*!'#!+**#""(*)&&("&""#(")*$''!'!#$*&%'+'('%&&'')!!!%#*'$'%&(+"'+*
@r7383
CATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACT
+
+!&!'!%++(*+#!*'"&"&)%*!"%+!$+$##()*%)!('+)+(%*''+$$"($)*&)#!))(
@r7384
TTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGCCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGG
+
5:7A0F1C=;5/:B(*9&.@@@HC'!30BC&51?D.A8B86@*D%,B*6$0"=HF1#,>>1:'$#+%3>$?$";689<0-3D4"*8)&59%+5B1H-."5A0EB'$1>E,.2?*'AE&BE70'E'6/2)(A>>-/04=$2=/?849EA!.
@r7385
TACGTGGTGTTTTTGATGACCCTGAAAATATCNGCTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCTGTTTGTCCGGACTAATGAGGTGCGGCAGCTGCGGCGTGGAGACACGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCNGATGATGGCGGAAGTTGTCATCTCTGGCTTGNACGGGGCGGACCGCCTGCCGTTA
+
?.#GEF!7G170$-)>.?9;$;D$6+<4$,:9"E.3(/8-.710!C(>&6:4"$&3CB6BA;-$71#5@8%A.FG&86>!%)@3??%#".)).+7*-F"@8(.4%)2?DD738,#G>3;"8@+)7EF54B5B+8%3<EHH.2&3$#.9C&%6;G@(2%("!@72=@07+###@?67+4;(0$-?'?B-:6H:2('D>%G@:.*/.4A@35?9#)"<).'.+;8HG
@r7386
TAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGCTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGNAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAA
+
D)#A4#88$&&.A80)HB>8@$!):C37&E>.<)$-!*)-!!C;H/8&'&?1$;H7=*A)'G$@E=,%5580<",/4073"?:=E0D<"(5$A6=,(A9"4&EC50AC4+F<"9C,F"H+3G+59,.H9=9/"@$.EE41%4%)<5:@;56:H%#C;';;*G80>-'D@1.$B$,741+$+=@+70+H*4.A+H%4>
@r7387
CNGTNACGATACTCAANNTAGTCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCCTGGCTGATTAAGTATGTCGATAAGGCGTTTCCATCNGTCACGTAATTTACGGGTGATTCGTTCAA
+
#()%!*"#*$)$*('&)!)(+'&&"&("&%(+)(!#*(*+&'!"(""'(*%!#($'&'%)$%!"**!%&$*)***)#+$#)"$!((($*%!"(')*'+$$!+*('%)%*&!%+!#&""&")$)'+"#
@r7388
AACCTATCATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGTATATGATGAAAGATANAAAATTAGGACGCTTATCGGANGTGAACGAATACTTTTTATNTGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCNTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGA
+
6G@+?2#++0@F-+6>,D22AC.&3+0;/517BH>0)@&%BH5''B#E#A/E(7BE)$>6"#H83B!1=<5<.E#.2#2,?6:&C->$(3.=:F<5*<7D/(#=:)8AG+E&-;88F;+E10/AA*GA2&42&2'*+0-@98&;<5#+?-9>@=A;!3*.0%F@*>D4<9:A.<E+30D'*.FAFF2;1"!1;0EDF>;=3.BH5*)4E!=#"?6H*872035>E1/7@8+#A973(D#*.'#/!!%D<=)<@<2%"7*2%!,")@$2+F<FA7@ED'+G?DB*#D&E)H@'"7$+.!,AA<3:
@r7389
TTATCGTTTTCTAACACGATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCNAAATCTTTTCGCACTTGATCGAATACTTCTTTA
+
9G5497.:"2#?)AG=C6!1"A759!A*E0HF-,2@'?F5/=$!1F>,:F6#7(4@C':3D1B;'!HBF%14?/>HG?F1=$3CE-$'3E/A#5(.8>@1&G.(B5H05%<<=>D6@&2C8CCE8-(#F")E/HD
@r7390
CGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCATCAGGGCTGCATCCACACTTTCACTCGGTGGGTTCCA
+
3,3"E5=.&-5$>7&,5,>4)DB-1.2;13G4B9+2."=E>)@0E1B-#'*E!4-3GC:#A8(1CF+6=?.>/"8?1#"?-(2
@r7391
AATGCATATGCATAACATCNTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATCTGAACGCGCTCTCCACTGCTTAATGACATTC
+
6,<?G?:)C(@#!$%-++FG(=B:6:-186C<1AH2@3;+>(>C+&6C=!(3G3G93"H;=:H$?9>:00?F.DB$7?GH+->D
@r7392
GAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACNGA
+
C&(8-8('(7H6:%#,0F>A4)1=D)@;12D@)./;>=-:'#H+7A*?%.;&&-*<86"
@r7393
GACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCG
+
>=0AH,/4%8+1;B&3@=F?:*0)H7-3AH7H'F(CE%"29#FD!G:7"$?9*EH?#!$1>;(G=4@)$<71&C)<30'.
@r7394
TTCTGCGGAAACCTAACATTGATTCAGGTACAGGNAGAAGGCGCATGAGACTCGAAGGCGTAGCTAAAGTTCATTCGCCAAAAAGCCCGATGAT
+
'@2-0')(>9$*.&3.;:<<%F(!18-&7!)#GA,61H$/+EE<&,;5.-)@%7469BB$91A0@"9E(D-3"&,,$0H%(<E/G&)$7*+01'
@r7395
CGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTTCATGTCGTTGGCAAGCGCCCATACCGGTTTTATGTCACGC
+
?7;/B'5(9384>AF#5D<7@@)4?E*0>9?6?C)47H1-';B-4G!1>9,H9@?%0+D<!5F:%3A24EH=D#%%//6!A-$G"5<!!9%,-?+<F/848
@r7396
GATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATNCGTCAGCGTGATGTTGCTNCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTG
+
DAFB%<GF.5$.A/G'92"1C'AH/D?E-!<8C6.@$#+F9D-%!"%+@>6,:A/FA!!/C-""+3?H;.//5:&'F9)1#=0DD1%%&?1#!=%.,"06#8H8#>(,#!)6'*,HB1*6+8.48&8!#>,C@/9:!(>,?.!H4$',/.E
@r7397
TNCAGGGCGCTGAAATTGGCTGTAGCGGAACCGCGCGCCATCATCCGG
+
+2B"-;5*0$EFH,3$8%"@2F*,;@425/4?)7FD/::%)/?@%C$%
@r7398
GTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGANGATGGATGC
+
*9E6C/<>23=7:41/4=1*GACG1F@AF@;;%BH8D2?%/6=6DG)12<G5841*
@r7399
AGATGGTCATCTTTTAACTCCATATACCGNCNATACCCGTATCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTNGTGC
+
5HE&,":(G)3#@+/!4+C%61.$.#/1$44)899%,0$-7BA=E/<<)26#$&6H91$7%3#.6(.3!CB28AF+6G-4;004"9
@r7400
GGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGNAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACNTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGAAGCAGAAA
+
32A"-B9./0DEH?B;9?"@"9)!7,22A=-D&**6'=08)?'&HG"G;E#90%6;>"3&EA25%(1&/)HB"5-+%,$H'8;%((&.8601EDG!A194%",2#B%'CB8G")G"*G2$><,'3!:A=?;#+-!EBG90/%@@:,)C.D6%?6:>7,F)C"&A.7!D?/'4&B-@#&?-$:&9157."?9&*9+(3(4#(&$1A2;,/-@B$(%D<2G#=@'0=(>8?:.39E7<5-$D
@r7401
NCATTCACCTCACGGATGTAGTCGCTGCCCATCGCATTCATGATGGCCCGCTGATAGGGCAGTGTTTCCCAGCGCCCTTCCGGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCNCCCATTCAACGGCGGTCTGTGGCCCCGGCTTGAACAGTGAGCGAAGCCCGGCGCGGACAA
+
!7@0%@#/9$BG3?"92=((4$D2B8$;9'B?=%<@D0FG(9,$$-<"6>/C92(3/G3$,5:F%9-4$+(0@&'"/HGF4"3,)326:3(8+E&$/939,B)7*3/>2"5:)7+0:AB.@?CC?GHB,:H/F7<@A!$GCE:A)<C52>87'!&=;,:<--!/8.+&2B.*-G7:82?)&
@r7402
TCACNNCGNAGTNTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGTCNCGGCGTTTGATGTATTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCNAGCACAATCGATGGTNTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCNCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACC
+
()'!"!)$'+''*"'%!$(*(+++&!'%%$)!(''#"')%$'+'"(&$!*%%+&$&"*"*+"#*!!%%*('*%"")&#%$%&)!)*'#*('++&$%+!%'$'$)+)&%&"%)!"('!'!"&+"+&'*%""&$*#)#$+!&()'%(+%('+"'#%+$'!)"!)%!"(*#*!&$"%$*%&*#+"!#*!+%%'+!$+&()))"&&+!"#%$$%%*&')+&&+"
@r7403
GANCAGTTCAGACGTATTCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCG
+
*($'+"&#(()'*%!%%'%($&+"+"+*'+'#$+'%!%%!++!)&+$"#!!!$&**#*%')""&%*(!*#+(#!!"%!)'#+""
@r7404
AGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCC
+
(.",4-7/B<06H=&22/9=1:$9-8GA4<@)!#C7)+"#
@r7405
TNCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTATGGTTTGATTCGATTTCGTCTACTGCTTCCTGCCCGATGCGGCTAATCAGTTCGANGCGATACGGAACGAGATTT
+
)!8FB'%.,3<7-/+*4G9;!9>'1/A7C#F=:+$FC3?B2!+)'2H0B-/G3=*EE'*-'!%,&>@C#H(2*%(;-@!,3(;"4.@6-D70=&B7!(E<9)<*5FAHHF!3$54D2.*4'
@r7406
GNACCTCCACGCTGACCGGGTTGCCACTTCCGTCAACCAGGCTTATCNGCGCGGTACCGGAG
+
#!"),F&8?B3<*B'0F'86193).@AC+-;1$2A#..%'3(B30%1;B&A33.((<+-*><
@r7407
TCNGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGG
+
)&"H@'D31.?G"#47!>.E;1;;!1?..9/>-%9;>(2,$E
@r7408
CTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATA
+
#BE(:D33B#5.DC<C!.#H(6!(<*G;B5$4,*00!8-E0:(C&!A7+)75%/$CHH@494>%@2?E'=G.FF(5B8763&6<0:>6"8A5H)<?F,?E&<G;G%!.<1)"!.3,.%F0/GA%4,/0E5266&3.$=)@7$2'<2#4!AH6
@r7409
ACGTGCTGCGGCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTGAATGATTTCCAGTTGCTACCGATTTTACATATTTTTNGCATGAGA
+
1<;>#BC4=33"3!:&13E7CH+'.>=*;0?@D@2H%4E8:)HG49-*>F$><F?=$E=(:)-6A"%!)+4E'?6D#B@A351C>2:$?
@r7410
GCCTTTGATTTCTTTCACGCTCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAG
+
???-C)0F072C;%%&":<#H520/:,5!;!8,@7?72/1"(4G>E0>-?#B7FF<1%/1<C&'F)@$!</-C.%)&G;9)&268F<$E%A#>=#EH$?;*)BE;*5A&<4%,6+=E$B(H*!4
@r7411
TGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAACGTCAGCCGGAACGCGACATC
+
2C91F/=<8.C%GGD)%>G-#02AFA*BG=/C=6!+;.5B2%H"&),@->><(+;C=@"29)3F=?8100%3+
@r7412
TTGTCGCCAAGTGCAGCCAGCTGGTGTTTGTACTCCAGCGTCTCATCT
+
)5#/A9.=/+4$'"5'=;9/40<;@A317"+0470.-*#4<'0E!H.2
@r7413
NACNTACTTTATGNGGCGGCGAAAATTCGTCGCATCCCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATNGTTCGCCGCGTGGTGACGTTACCTTCAAAGGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCA
+
&!''+"+#)#*&(!''&(($#+("**)()*)+*)#$')%!#+()##*$%#*("&%#)#%%)$%*(&"#)+*+)*#&+#!*)$''%(+##"$'%'+%+!*$'"'$')%(!!"()!#!"#*%+)"&*!%))*'()+"'"(%$+"&&%('(!!(*%"!)$+'%+*&&%!+$*)$!%"!*""*'*"!(!
@r7414
CCATGCCGTAGCGCAGATGGGTCAGNATATCCCACAGACACCAGGCCATGTTGTTGCTGTATGCCGGNTTAAACGTTCCGTCCCAGATACCG
+
D0>1=990$!5A&@>7G3+!,)@*-<=C+165(:'/4/@D&!G$'G=0$4#7%6>''F<0$89HG&18.EA>E8$G0*&1;'D/5&27:&?)
@r7415
CGCCTGANANGNAACNTTGGCACTCTTTNGACGNTGGCCGAANGNANTGCGCGGGCGTTCAAATCCATGTGGGATG
+
%')$#!%"#""$*(#!)!(''%*%($#(#*(#!""*#'$("!#*""%+&%**$(#&%!**"&*!&%$(!*+)'(#"
@r7416
GTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGCGCGACAGCTGAAGCTATATCTTCTGCACGTTTTGCCGNATTTTTTGCACGTATTGCCGCCGCTTCNGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTNTGCGTCTGCCGCGGCAGAGG
+
(CC@C%G9;6H97>,(:%&0=-?E/9(*(4B-$B6G)C+,/&*&B*)+F6=00F/),#D24>=@1<5"E(HG(73#*C'CEB)G%;-5#5,,D.==23:E:(=-F$:4>$H=&&??.E2;01<<$@8+/G>B&6D./!EHD20)!2949(G>-5(36,8H;$2E=,!&9!&21B<!A9+D7?)11G>>#4H59(GFA**#0;++B2H.4:;6%3"0*-E<:##$?G;>C>9+:4E8=,)6(AA,#&(=-@8=$&2=8)>/");0&-"A@:;/@B-9&F+56<3FGCA(H+E0.(BF;D?!<D1*%E/71085"@3*";'6)*GG>?%8A&#@7)#9GFD<F.>@1BG7.9,23A
@r7417
GGGCATTGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGNCCCGCCGCCTGAAAGAGAACATGGGCACGCTGGAG
+
%*=/9D)-#<34;*DE*A5.;$0>D%1.C1D5A1&88!>B4F+-+7%E!.,"B88,-!.7A0F<;:+9=#$FB4>BE"E1$%7#E3
@r7418
AAGGCGGNGCNGCTTTATTTAATGGCATCAATGCATTAANTGCTTATAACGCCGCATTGNTTGCAAAAATTCTCAAAGTNAGCGTTGAAGAATTTAGCCCTTCACTCGCCAGAGAAATCTACGAGATGTNTGAAGCGGTTAGTATGCAGCCGTCACTTAGAAGT
+
"(')(($"$&!)+*%+!*%'*'(&$&&$#!(#$*))+#+$##'"$(&"'#$*")*%(&&)&+!)&)+%%#&*"%+(&***+(%(#!'&'$*"#*&"%*&*')((''(+)"(+*+"(&')#+*"%'+#%)))&*&$%)&+*$%%$+('*$'(&)(&*('%!)*$!
@r7419
TGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGA
+
/:$CF5?E%*34D($,H77:G,"D%9AD'7E/<C-%@B.(-:-F.G53*(
@r7420
GTTTCGGNATTTTTNATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGAGTCGGCTAGCCTGGTTAGC
+
G1>+75,;F@28D;:/-?8.47(>@(-<*FE$$CC/AD,2>22<$3E6-%H$D?:9"=6,9G'0BH@/9D6:74A71.#
@r7421
NTTTGCCCAAAGCGCATTNCATAATCTTTCAGGGTTATGCGTTGTTCCATACA
+
#6;;-$(2($&2<5,6/!3?F7C:G/:;1<@2:A3>+H#<:8FCB728/+:2$
@r7422
AANNANGNCCTGTAAGAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAAT
+
''%$!"*)$)+#)&(&$&%))&#+*#(*#)++'!"$++*$+"&##")##+''"#*+"
@r7423
GCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTT
+
69H;?(7;#B*<9)&%.DE+0*8%?HF'/E'&(&33-"-1FG&#>+FH,6+1=&,%2&4?
@r7424
CAGGCGCTCCTGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACTCCAGCGTATCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCC
+
(%'F%%-#*A03%/.F-&=-A@"*??4E+862(-G$,9F&-?BB:9B;H"-%C;A4.3-@:;;/,:G@&%/13%62=&?5&3!.(G-4E?3+FD+HH#8=.$$.9?=27;EF!!E@H!85HH:E10?B;E
@r7425
GGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATACA
+
;(%:,8=4;-C2/%4%CH85#'20>0.$7):0?*:F;1%B7;>%%*
@r7426
CANGNGGTNTTACTTCTGCTATTTCGCAGGTCNTNGAGTTTCT
+
$("'()$"%&#)#+'"!$!$+("#&+&(&++!)$""()+*$)*
@r7427
CTCACAACAATGAGTGGCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTANTGC
+
+$@-<::#$5>F1)24H&320G$*;+7B@.:58)/.>0/48A9A'?&!&4@@$"C$=
@r7428
NNNAGAACNGTCCNNAACACTTNATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAG
+
%!$$#'*&#))&#"%')#%#!#&%'+')&!&))&&$"#!)()($++'%!"+#(!')$'#'+##
@r7429
CCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTNACCNGGCAGGGGCGACAGTATCAGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCC
+
HF),B><12HB(?B:-?B>-$7$%C<"</4*D@B;3C>D#7>F+8,,'7(;;H99157?>;><H8#?B6*++F5<!=&--B!$:*1H"4<H,!3>-4"=C@?GF&/@%E>9F4C,<<ADD!6!/"=;)B&H8!G<-4>5+6"7F!(<?>..<F2?$<G/11@*""1(/)&#1&?%6274FD*?09-"80.;3D)-4&3%0$#B%/+,07>%//;3597,&68",+5BG56)$+EC!-61E<$$2/CF57.1
@r7430
GTCAGCCGNACCGCGACATCACTCNGGTTAAGGATGAAACCATGCAGGAGATTAACNC
+
&+'%#$'!%%+'!+")!$'*'*%&*'"+*$*'+#')!!*#&)#%($"$*#(*%&+%("
@r7431
NTNGCGGCCAGAATCTCTATCTGGATAATCTGGAGGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGATNTTTTGGTTCATCAGTGC
+
&)$"(&*$+##%"%#!!!+'"&*)$#)&)"!#(*%&&&)'$%&#!)&+"'!$#)&*("%*''%'%*$"+)*)*"(+!%)+'&+)($!)!%)**#&%"&(#%$+#!""'"))&!%
@r7432
TCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACC
+
.7@;9+CH.<:0@ED@7,!1;)D1.7"2=2(%D(F>#!$5":1%
@r7433
CTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATC
+
9GDH;>01B&$2G@1;$E%/0),+G9:D&GF3H$*#6%0H/D864&-E!41=2E4%%
@r7434
GGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAA
+
-721,%<H(G493%8G?:'5%%:*'8,'253%+6@D7;=+'8;G,19(%19A,AA:1H@,/:H-28$"F(??>6B<$)5*)
@r7435
AGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGGTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGNACGTTGGCTGGTCATATTCATCCGCG
+
5$D&69(0=0@&60FA?97A4B*B>0(5'5HG).<411578:+;-A0>&31$7?51,/<H!EG61B;"G9BD1724;&@!2+?$%/,F@'B;#&FF=9&21:;!
@r7436
AATGTTTTATCTTNCTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAAATGTTTNTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGCAAAT
+
9++.(.6&)(&9E8F?FG,?5+@7C#(G4/%):#GB92=4ABG2()2;!*ECE3"&),F(?0*DD'E7A=,-98:)>+#"B*#""05(*93,33$?AGGB/(!'):/-EA;6>02955?->BA/@:8)1;>@0%)$&/15/*31?&0GA71>957C3$65,F/'>)/.FF5&2*6F,A&(:$?/6<F)
@r7437
TTGACTACTATGTTAATCTGAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGT
+
/$%*25DA<468?!>F%>GAF4@F"'1>,A*$A'4.@/>3)2=B&1:<./)287</H&#H4D$A>+#2DDFC8''7G,F<;HC$6%G9/'3"'C!&%?4.35FE7"0($H4.045&$;
@r7438
NGCNNANNNACCNAAAATTTTGGTATATGCTTNNATNAATTTTTTCGTAATAGCACATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATNAACGTNTTTTCTGACCGTACCGCGANTACATTTCAGTCTGCGTGCTACTTCTGT
+
*(!#''%"(!(($'!"'#%)!*&*#(#(()'!!#'#&+#$&'"+(&+(#(*%&%('$$+"!$)""+)**!#"''"#(#$$&!+'#%+*#'!""(*%$"&&"+&)"*&)$*!(+)""*"#!%$*%#&!#**$++'&$)$(++""%#%)+(%")&'!+!&#!!"%"#*#(**##&$+"$$'+""'*$
@r7439
ANCNNNNTGNAGNNNNNNATAAANNNTNNCTGNTTGNNCGACNTNCCNNNNNNTCCNGNNGCGCCANNNGGNNANTNNAANNATAGCCTCANNCCAANCTNCAANCTNTTNTNNTATATGANGANAANGANNANCCT
+
#$!!##$#$!"$#!#"#!""$#"!!#!#"""#!""#!!""!!!#!"$!!"!#$#!$"#$!##!#"$$#!#$!!$#"!#!$""""$#!"!!"#!""$#$##$!$!"!$#!$#"!#"#"$###"$#"$#!$"$"$#$#$
@r7440
GGGNNGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCNGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCNGAAATCCACTGAAAGCANAGCGGCTGGCTGAGGAGATAAATAATAGACGAGGGGCTG
+
)''!&+!)!%+$$%"'$*"*)+*()*(#&**%)!+)%)!#(''*+(%+!$%(!&("&$'##"'%$+)$"!!$&$&(%+)&)$*&(#'%!#&)#$#&(+&%!%)((#%+!(!!'"&)"(&#+"#$"++%&'&%*(+"%%$!)"'+('+$(#+$#''#!%)"%)*$$$$'!*''+#$&($('(!((%''$!&!))!(+#$'""#!+''(#&$"!(+$#!""#!)%"%%"("#!(%%&)$!)'+##%%(#!$$"$!#)#%&#(
@r7441
CTGTCGGGCATAGCTGATATTTTCAGGGTCATCAAAAACACCACGTATCACCGCACCTGACTGCTCACCGGATGTAATGGTGGCTGACGTTCCCATGTACCCGCGTATCGTTTCATCGNCGCGGGCAATGGCAGCATCGAACAGG
+
9,$E7E6)#=07.3777:*:><2&7>")3:9==AHC'.&8E0D"(692GB:A&92A3E31!D5:'5&A#F6B$%6)9?4*%(6G-B.6-)E0/5*HG-G>=$F3.:B,H2?A>)?7,=;17"<7+3*$>GA4<DCDG?#0#'(!2
@r7442
AGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCAATATCAAANCGGGCCATT
+
.476D$A)F5-8-A!B@!!@?:.G&6@;8E"8E@;?=GH3/G>,G>;%(:<1*7%'/#)+'@;8>?,%/9,EB2%@A?:H)/%B45&=03$C7BFF"@)
@r7443
TCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGA
+
9!),?'5%+!72534/GB/%'./'G3H3)(5&B%A>*!C!7'+?.&DEF9$#?C-70</,=;@#1G%!;1;;"#8.=6C!84G$,1-9>"3/D2<&>FB>>/."EG+A!5/*F/C*&.#5(FFH@0>(1,F)<8%1<!7!"&#)!9"15C2BD<H#%($GE?(<,'?<<>+).6?-14,4@73".,;(<$$<9&=&F,E8-9=:F7%G!EE-A#BE4)5!@!4
@r7444
AANTATANCNGGNCTATCCGTATGACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAATGGATGCAAGC
+
%&!!&'*!%&('#%!+)+"%')(%(++#('"$$*&'$!&%*''"%%+#*#%("'$'!)$'+#$)**')+"""&*!""$$""&'$$
@r7445
NACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTT
+
%HE'-H""&?!G)$:2FB<3%CEF!/';@11'4,=H;*!9:/)<AHE0,)/H?=9E4$)'%=@1.$C0A@-5$,<-'!=E",$:H425-$;.?/;/..2(6<9F%7-?@7+<.!<,A+78?2$,A)<)36>C&A25FA6DC)3;8%9/?G);
@r7446
GNTNNTATGNNTAACAGAGTCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCGTTTGCTATCTC
+
*#""!'&')"%*&"(*&$(+%(**''%&*'&+$!!+!!+*&%#)!+)%%$)**+$"&$$&+"!"!*(#"&+)'+&%'%
@r7447
GAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCAC
+
45%71@<)0@/:=H4?B!B>F9AE1%B$D75.1AG)-A:GE?=C9**(639/(7:+,5(:095-E.?.%-
@r7448
GCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAANGCGACGTGCGTCCTCAAGC
+
!,":254E/#)"0!"&'3?C>H<.B.>3"-3:0;8>&55*C$'4?"=CC#3%>.D*,:3?0GB9/1>%E9.-&95ECB*%E$@'9:0DAG=$<%F#G'=;+:H)#(;D%3H2-2F@F>>C)A&&="-.//<"/."
@r7449
TCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCC
+
=E:,+-48?("!/:D!/329!$)(7/()1--<,!/9-1*"#*D3860B6D18&8B%
@r7450
NCCCAAGCCAATCCCAAAAGAATCTGACGTAAAAACCTTCAACTA
+
=16;F7=E(D>G=?0$A=/<(A1),D-01*23F*+23,'+7A"!,
@r7451
ACATCTGCAATCGCGGCCAGTACAAAAGCGNTGTTCGCAATCTGGGTATTGTTTGTT
+
F*<=8C4/1#+%1;@H#H%96H#"?<1B<..HF6$7<&076C%>1D2;#!):BF"!.
@r7452
AAGGAGGTCANACCANATTGAAACGATANAAACGATAATGCAAACTACGCGCCCTCGTANCACATGGAAGGTTTTACCAATGGCTCAGGTTGCCA
+
'%+%(!+(%!'$%+&##!$$#&(+#&(&"*#*#%!%+)$(*&"%$()"+('#$$!%+'''&*+$$+&$)!)**)*'*&%#*'+"$''"#($!&&)
@r7453
GCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCGCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATNTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAANNAACTCTTCTGTCGAAGTGATAT
+
*D?/4):..)*=@#2893!#*H;1$?1="G20#+1#2C5$D%F2>7A25H:87C9C@%?%!1;9+<E$8(;49>5D/@G3937%=%G33A!H:1%+/-')8/%H%.;'<G!87-/.,:!.(>!>9G.EH%:6B$((/#=G?377$3,+A=@;B(;)*=",-2?63!AF:5%(80=H-"$<C458A-%(-H9-GHB.$9>'2%+&&+/4=3G&"0!DDH!%);F*8,7-@C8?GC9%3
@r7454
CTTAAATTTGGNGACAAAGAGACGCCGTTTGGCCTCAAATGGACG
+
.=A$40G41%FA&<445:A5HH<$0A4$E/.;C4%*->9<=95!C
@r7455
ANNNAACTTTGCCGGACANGAGCGTAATGTGGCAGATCTCGATGATGGCTACGCCAGACTATCAAATATGCTGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACAGTTTANAGTGCTGCTTGCCATTCNGCGCAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGA
+
&%#()((+")**)&$"%!*'+'!&$((**$*%"*&&#%#("*")*"()!")'+!#!)$*('&+("""!#!"#')*('*()%$+$*)#%)(&)#(*)+!&%"!(#*!#**&$($'"&&)%$(%(!"''!'*#&&*(&#+"#$&%!'%!#&*++%#+$*'(%+)'&%&')&!*$$!#)+'#)
@r7456
GCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTANCTTCCGCTCCT
+
;D?%%=#057!H+4/A9"24F%B>2'259FH)7?@&5;6+B4#-)"3B'7=7D.,FE$<G4$>E.B5$?G*3@/,*#8.?D=6B>&>=@
@r7457
CTAAGGNATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGCGGCGTGTTTGTGCATNCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCNTGAACGAAAACCNCCCGCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAGTTTTTAA
+
(*!"!$"'&+*#%%)"+(#"*$%#$*+("##%(%)$!)+%*"()+!(*(&+&((*$#$*)$*$!+)%#(&+(++$&#)&(+%!$$!&'+)!#$'("##+*"!'%$!&+%*'*+#&%("&$%+'!'!))!'%&&#*)*(*"$""+'((&%*('%&!%#+!$(''&$#"%&((*$+%("#'%''!*&"#)"%#')!"*)&**(!!&$&+#'(!"+%#(+&&!"!"'&%!!)!*(!+!+!$)&"#+"!%!#))(''#'!+!%%#&!"(&!"'!$''"$+""*)$&($&&&'!"%#(()'&$&(*'!'*#%!"#&%)!(($*++''"#%#+"'!&(%+$+''+%+&&&*('!%+++
@r7458
TACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCNACCTGCA
+
-!/&,:#9G5>3#D2;)/;;.,>,00B3";D(F#<&6;;6*+E(@H8C#
@r7459
CGTTCNNTATGCCNNCCAGTCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGTAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTG
+
&''()"&)''&*&&%)*&"+#++&'%'"&"*'++(+&#$)+)$&%&)'%"*%#%"&&)&*%+&$&&+$"'+$%*$!$)&%%+$#$#+$)%)$$$"*&"$!''$&+$"!*+"$'$)(%&'%#+))#%('#$'(*!$)"##+&''*!*)&'""*&"
@r7460
TGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATA
+
.>-#,';$2@;4>=3H.GD9%<B=>+@B@)8'3<,9$F='=7(;(8E!3<<!*H7'#$'')(7&1.@'BB;1-3/7<.15B3.DF0#D!/B)24:0H8H<"5##75&:H2(2#5)<A:;(%<:?!>(/08&/=:%(H3'#+3:';?B,3*9-E9-/%+1,**95?)5*9,(!&C,>62@*D(7'FH8=D!1D.:4(C/)>011*C'?*42/)4&H"/;2,&.G:0?G;-)-52A-$D,F@H1
@r7461
TTTACCGCCGGAGCCACCCTTGCAGCATGGGGGGCAGCCATTGGGGCCGGTGGTATGACCGGCATCCTGTTTTCTCTCGGTGC
+
%"27&84G%!#/2<!8H,AE!?5C.<#?##5%8"/:2E(1H*8=C&'G=<(ED/F01DEH03-&@*.886?CD1=!/EG7AD<
@r7462
TGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAG
+
:@70*2:/:)3A";>57="#?35?!)7#$D"$''5'8C@9-:=8>,:E0+
@r7463
ACATTGTNNNNAAGGAATAGTCATTCCAACCATCTGCGCGTAGGAATGCCTTATTTTTTTCTACTGCAGG
+
)#&%**)&%$$+*#*%"+)"+#%#)"%"%%$$$($'#"%""*!+('*'$'#)!!"&)'*((&%"!()#")
@r7464
NTNACCGGCTCACCTTTTTCGTTCTGCTCATTACACAAAAAATAACGTTCTCCACCGACCTCTGTCAAGTCGATTTCCCAGAGCACCANGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGATATCCTGCATCAGTTCACCACCTG
+
"*#3>4'",4-D@!$=D>':.;'&"+,/</:23;;4;40,4AE9-H/(<)3&#C"C<@#4?H"9867"8%H2;#"DEB?F81;/)9?2:-C829.2/8$-$)@#$6G00*.E),9@=;(:-AH4<%8(D=/D::84:.F9-C4DA*HB0$%2B>1)FC@:(BA
@r7465
GGAGGCTGCATTATCCANGCCGGAGGCGGTGGNGGCTTCACGCACTG
+
,AA;9.9A)E<A16:;>&"7@3FA!G!A?'"H=C9BD#%<E+#84*7
@r7466
AGACGTATCCAGANTCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCTGCCACNCG
+
B$6618(@45:=$:(38%-9G$,0$E.84B.>+'G5<G6"6@!3-.!<<</&8GC"'<<H%,5?%.H+)-G#4@(H<56)A0+/.$6;#6G,GH"&,4=H%A.@5BD8:*#1B)A7+:B0@F+"8D:H05:)*(33=#*15H7G
@r7467
GCGGCAGCCCCCAGGACAATCTGGAATACGCCACCTGACTTGGCCCCGGCGACTCTGGGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGA
+
9'8%74###0%$/11BAFB6GF<:@D"8-;D.4<DH<"D82="-!FA%!1%7D',@>B'(GF"51*E/B4E27D;/522C-<1,?06-#2@0%"",244&*'+GG#110B*?F$5%+C3
@r7468
ACCTGACCCAGCAAAAGGTACACAATAGTTTTATATTGGACTCAAGAAT
+
C;(4>82'B(+A#<"=='4A=G'/@)GE?;1<&?D=F>!/%FA@.--2H
@r7469
TGACATACATTAATAAATANTAACAATATGAAATTTCAANTCATTGTTTAGGG
+
5,)"(;-94)))CC$1C<%$')'D*$4+.8(9A4$@G@1BC##HB=5+<DE:.
@r7470
CCCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTGGCGGCAACA
+
#;7D7-$)3=/4(33.E#>G3*,7*A77E.6H6<&0278)@F%&.A=*)1:05(/-!&3="5>:D,B7B6*@F38##48>.&$(.
@r7471
GATTNNGNCNGCAGGCGTCGTAAAAAGGGNCAGCGTTGATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCNGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTGGTG
+
$$()!!#&)!+"%&!#%("'"(()+#*+!"#")&#*%"+$"+(!'!"+!#""*+#%!%&"$)('))&!($!&+)%*$(%'!#$#!')*%#!"&'(+!')!$+#%%##%&$$((&&$+$'+*+%""$#')!%&$''"$)$)'"!(*($$+))+""!+)(!"'('##"!*)&$+*&!)$
@r7472
AAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGTGCTGTCGAACAGGGTGATGATGCGTGGCACAAATTACGGCTCGGNGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTNACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGG
+
0E:64&2$03B'!6>=;*?"5:F9)E0.;#=)$=1A:D8="CG7-=H00EG9H)(&/'AH&F*A8D'/00F?@3+*%H$G@A1H'D"?F7!(F(18#6E8695:*%4&0%")5=(15##!*E;)HH!<'?A>D!H$B:>231,!E,&?<2,2;74*B.@G3".A9,4G(.285@0<3+8.7!C97/!B@HE@+35!@0(E,C)7
@r7473
GTTATCCCCGCTNCCCCGGATGTGGCGGACATGACGTAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGCGAT
+
(?,:;@BH5GA3;#3$:H7$((5G/G93=G*9#(68.%&'()H"3!;.1#5-!FDA:3)1*)%$492./+3=<1G?EDB;=,%E1H<A-13%+"+C>-,!="%B'D'%HB'A
@r7474
ATGTGCATCGTTTTAATTATTACCGGACACTCCCGCAGAGAATTTCCCCGTCAGG
+
"*E>H;6C4>?G$$)*7C40H4%)H--,"E3(4'0'&?<:.>(:-=*-+4:3F6F
@r7475
TNGATACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAGTAGACTATATCGTTGGTATA
+
(#&!'+)&!$("(%!!*+(&%%&$(&!*+**)!)#++!*(%&")!'(*!)%#'$"+"!))#++$)++++"+!"#"%#%'!)
@r7476
AAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGA
+
;8945?G?1-B=/#6@3F?;B2+A20*1$9'A;*3!'(2=
@r7477
NAAATACCGGAANATCTCGGTAACTGCATATTCTGCATTAAAAAATNAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGG
+
"?D80C50..9><@4DG&!(>(-ABG+*=5H"=/C05/0H-%=$-9=)=A0BBB!>7:=81:%0625E%,36=%A#88(2B5F2'%
@r7478
CCACCATCAGTTCAAGACGCCGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGAAGACA
+
9!E<'.>GG+&:D.83>?75+'=.-9/GDDF>&H,FD?.+2.&!1>*A17?35:2;"1*.4BH;-/,<:+HB/<E)7,).E?422>D?..!C)A;>-!"0E710D(077@@2/%06?F(<19(+7!51H!*0)!%&>-5)$#()-30))B:44#&
@r7479
GTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTAAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAACAAT
+
-9DH,<G88)F?1/5/9>F$:GH?1..)2A+<%%8'!F&'/$(:G5@')6"+@/:8A7-6E-0/0@)D$=@(3,<.E1!+,5-#+0DG&"1:!<D?D0,9,6A"H<90-0#CD29">!>$2=G+"2$88,)D$42>@+5F59,H,&
@r7480
NTCTTCCCTNGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAG
+
""A5C/@,99E5.@0F.BC!?>13(8C>?1(C4BH<-2<C%%$CE0E7/C/1/=37-8<83>4
@r7481
AACTCAAACTGTACCGTCGGGTCNTAAACGGCAAGATGCGGCGTGGC
+
+@7!H#B16$,5=CH;D?BC$*?-!@$E?2GH;=G>5+3@6#F6,F0
@r7482
CCGGAAACTACTGTCTGGCTTTTTTTGATTTCAGAATTAGCCTGACGGGCAATGCTGCGAAGGGCGTTTTCCTG
+
H'%.$0:(6;C#&7G(9,&)A:'"6H)&@D89>B-'HBHC/%=BB=B'&'D3D,2-196CDG-".-F?9DH*C3
@r7483
CGCGCATAGGCNGGTTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTTCTCCTCCTCTGTTGATTGTCGCAGCCCGGATTCAAATGCTGCAGCCGCCCAGGCGGNCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTC
+
)0:.#5.)AF#),@63;*'?2&-6=A8G>:$>0+"30)E:&:;:*>/=05E.@7'*E09(#4(;@.1488)BF8B.6'H0>%.AC@?;=6;,4G;C*-6'GCG7$8EC<,:"#*'.<".,857D%!C&9.?/3E7<4+2@4;"(D#*>.>(11*4&2<"9D;'6?<!.5-1##.'!>*><9),=*-0F?!$=;$E7$+HC%#0HG?1$7,2'.+)=
@r7484
AAGCAGGACCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGT
+
C(:F;'(FH"2$)(F7<7C%HG1?8'<@-F$-(='&C"!05'
@r7485
CGGTGAGACGTGGGAGGCGAAAATTGGCGAACGTCCGTGAAGTGNTGGCAGAGCGGAAAGAGAATTATTCAGCGCCCGTTCCTGACCGTGTGGCNTACCTCCCGGTATCGACTCCCAGCTGGA
+
<A<=1!5!>DF3/%:G4G(G7$D&;@-HF9/@)#)*E2;F4B*#%#D39<(+=*2A:04;>,H$F+&3-%GG&:AE777C>52D$=#@1*$&D7+4/F5>(;;?;H#,B&(/;+!A<$6!&<:
@r7486
GCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTNTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGTTTNTCTGCGGGTTATT
+
E-@*!0F$H$,#8>;6.='*B0!%>&5)BF'F@/6<'/>G1A+0?&,!DH=*49/#,=EFG83BF;A0-0=+9(-F2=7,)>%0'%8)E-F))?2FEBH+/D6>;&1;@."A(9,:4D%(',9.3C<+;8((G*H#0&9&3G/(3D4);"<)!??1(7:73F=H?H/:76",A'&581>"=/CB");?2*7ECD1%"@7;H7A)&/#$*&=H$:.;5$7,D!2DBG3A'*)+$2A8()B3'H)#0*<":60B4:@0G9+)D3B'7)GH2<6H%5?6,<2;>,,@!E$$!%/CC9&)62@AF.E17=DF9.&,4<;46E01.5?#CGD1?F*,9*E(9==EE!B*(?<@<D9%<'/=G&,"++AG+*%>,6#'?EBH!9/88=;6!C,!"DDG$H
@r7487
CCTTCACGCTTCATACGCGGGTCATAGTTGGCANAGTACCA
+
)'*('*!$++%*+&*&!)+"+*'+'*+%'(&$()!(&$'#!
@r7488
ATGCTCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGCCATCGTCAACGACNTTC
+
03,(2?&29E;9>/$81/6F@3"69C.8G70%0>!>66$0@"#/)6156BB3*//@:C2%=+9G.C),+9*3##4&!?C!!E/$-%9</*./D#;8"CH$%B@04'A/H5'H%%2@B9G16%CE
@r7489
GAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAA
+
/$36=<8<(6E"0&@A")>!22:$84:&;=8%5G'5%B;>!?*/0F8?!.F?&>AAD//@49'+(5@>4"<.?:'81=*
@r7490
TCAACTCACTAATGTATGGGAATTGTTTTGATGTAACCACATACTTCCTGCCTTCATTAAGGGCTGCGCACAAAACCATAGATTGCTCTTCTGTAAGGTTTTGAATTACTGATCGCACTTTATCGTTTTGCNTCTTAANGCGTTTTCTTAGCTTAAATCGCT
+
;4F%E/8A"8+E8>9F.)=(6*/$%"=A8;1!4G;@B74@;2?:6H++;E2-D<#>G4>B68+3GG&"$B-B<3<9F'$.F!(!/@=;/>3/)80?%$'%D-%!02'%,#-"GGEA9HDH8:HGFE+)*9.5.<)8'C0+$1+9>&3A+B)!12A/A&+7D/
@r7491
TCCCTGCTGGCGCATAAAGATGAGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACAAGGTTACGTATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCGGATAAATTCGCACAGCAGCAACGGGCAAAACGCAGGGCCGCCATTGATGCGAAAAGCCCGGGGCTGACTGACCGGCAGGCAGAACGGGA
+
=G''-&'E..*??:@HFE<E9"6/7'A#@/.E+$'GHD(.11<"*@:%8>H1((E>2!F51-A9%8B,"+1'/65'3.;F8$"$F.5>)=>'9H4%8@!!56F1*E)6;6:CFH!.!76!("431=H)F1"+!&=?=3G/D#B7!HG.E$+D+416:!>@E5%"+&EC2B=<A,B%>9',1%(E+7>7#%+:('1%?
@r7492
GACTACGACTATTGATAAAAATCAATGGTGTGGACAATTCAAG
+
F9F?431(+#'79#)+45;/&,)#C&F00G/<57GA9CE(HB-
@r7493
ACAGTACGGGTACCTGACGGCCAGTCCACACTCCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTC
+
2C#649AA'!<GC9"9349?#$&B",ABE@;=$'0F.:#C:AH#4G93/;7"'&/2!CA*A<##-(5E"%B>8CE*+'F:0G48<:>H>%C86>,D8)H
@r7494
TACCCGCAGAACANCAACCCGCAACATCCGCTTTCCTAACCAAATGATTGAACAAATTAACATCG
+
"*+('+)!%#*#&&##"&+$()"+*(&'(!')+)%%+&#&**$)&!!")))))%&%+**+*')(*
@r7495
TCGCTCATCAGTTCTGCGCAGCAGTGCNCACACACGTGAACTTCCNGCACATGCAGCTTCNNACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTT
+
7+'BA18;<C@E*<G('&<'&$;<6%+2-;76#0;3E;BB*=#,B/&B4#HH+;62/)(+0070D56@!#69'6.=.?+@4E(/:.GA&!-8E6B9G#5*54@&*?C$$6$!+@<3!-%8>
@r7496
CTNANNAGTGATNCGATAGCTGAAAACTGTACGATAAACGGNACGCTGAGGGCAAANATCGTCGGGGNCATTGTAAAG
+
$()%!!)(%)()')&+!)(!(%$"$"#&"*$%!+$%))"*"##**'(+!'"!$'#)()""&%&%&*%*)!*''("*#%
@r7497
TCTTTTGTCCACGGATNAAGGCCGTACTGGTTGGCAACGATCAGTAATGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTGATCAGTTC
+
%'&+)&!+++!")#!%+&'&!''%")(+"+"($()&'&&%&$&!$")+(+"$#))!!)!#&"%"+'+&("#+)$#""!'&%*"!'&*(%%*+(*&(('&("%!*%+!#++!")
@r7498
NCGGNNGTNATCCGNCNTCCTGAGCAGGAGCAGACTCCGCCGGAGGGATTNGAATCCTCCGGCTCCGAGACGG
+
!')&!"&*!"$$##'!#%$#$+'*(*&')(*"$#+!&+&('!(#*&#"*+!)+#*%)*'((%!""&'+!#*+*
@r7499
AAAGGTCTGCGTGGCTGCACTTTTTACCTGCGAGATACTGT
+
72929-.64=B+,+&B)G-H<')F54C'DG.>82161=BB%
@r7500
CTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATGGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTT
+
5<5:01;.$#H()A77!=%9?<&-G57F8-G2F*?7)+%A+?!B-0+(A".9G<,##,$%.;2,A)E@5"/)'+(4@!(1*&DD)3'.A5,*79
@r7501
GATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACNTCAATGCAGAAACAGTCATCCTCGGCANACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCNCCGATGCCCAGATAGCGCCAGCTTGG
+
"%+!"'!(#'&"+))'+%)!*(""!#%#!)&"$*+*&''*'&$+&))$(+"+%'"&!&!*+!!&($*#+&*!(##&$*+($%+!##$$"&'))')')'(*"+'*%*'+(*%*#'%#"!!"#!$**)*%(#%$*)*!*'#)$"&&&*'!"'+*+&"()%%
@r7502
NGATGCTAANGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCA
+
#05#*?(B#?A(3)D)@.8&E!&;2:8>?H+C1$0,?!B<*2481A".E"=(@-.)!"C%F#.D:05*
@r7503
NTGTGCCGTCTTTCNGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGNTT
+
+#!!&!("&+'*"#+!&+&*'#%)&+'"""+&%"#*(+)&$"*(#$#+&%(('!()!)&(+$"&$)"*
@r7504
ATTCGGTACAGAGCGTGGCGTTAAGTGCTCAGACGAAGCGAGACTGNCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGNCGTTAGTTTCTCCGGTGGCAGGACGTAAGCATATTTGCTCTNGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCNATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATATNAACCCG
+
+#'$"#+'!&!"!(!!!(%#)((***)(%+)&'+"(%"**&$#%!&)'&+)$+$(&))%(%#$(%$&%%&##&!$%#*+!%%*'"*!%%%+"+*&&'++'(**"$&$*)*'#$"(#&"*+$&#+#''+&($+$#%!#'&)($&)#)*)(&$)$("+$$*'('&!%$$+'&(($**"&%'%*"!&)##!#)))'*)!!!")!''+#!($"&'(%*"($!%('#"(%"$+$'#"%&+#"!&+!&(#*(+)$!"*+&$(++%$"!("%"$''!!&!!)'(#$"$(+")(#*
@r7505
NTAAAACACCTAAGTTCTCACCGAATGTCTCAATATCNGGACG
+
+%(+%$(%*(!$'$&$+'&+"#$)*&*!%&&!$+)!##($$($
@r7506
ATAATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACA
+
?80@C/,.:;>G2#D-6FF1:"#B*DCG*><5C,H5#53H/;
@r7507
CGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTTGGCTTTATCTCAATATTATANGGATCATAGCTGGCAACTAATTCAGTCCAGTAAATATCCTCAATAGGCAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAAT
+
!&("=,::#H/A3BH7,#741-%>/#9(39("%)4'%"<&38!?)&0@F>,:4",B?F!CG@5H39+/;(A"9=5+D?36;+HF9AG&06B-1,=HG31G6/-25C%;>4?E>0!.A;+!D+D$E3,+1!5'H;0/0B!/D:A+/%$'65$@,C.?,-*).<"?"-!1<"E484@E<0)GG:4+73762!E7$4=4+&4'=4F,G4.<0/?.8/4H"->1,*
@r7508
GAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATCCGGTAATGGTG
+
#)-$F%6-$'-65CB;>93@#+9&0;68<3*826+)G58+;F)G5443F&@H+
@r7509
AAGAGCNTACGANNNATNANCNCTNNNTNNNACNCATNGNNGCTANNTCNNNANNNGNNGNNGNCTT
+
#!"$$!!"##!#!!$#$$"#$$$!"!#$"#"$"""$#!#!"#$#$!!#""####"$#!#"""#"!!#
@r7510
TTTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCTGGTC
+
A8'/GG>54E6;!*'&D.-<6<)/&'/'F7"=<1()FE$>:1)G33AG9>?%142%G:/"$@<'G7:%;D#5:E%2D6A)'A1BD&/'$D#+07F$/!0(-5?=:'72DH*$*C(=<@
@r7511
CGCGNTNCGTTTTTTCGTCTCGTCGCTNGCAGCCTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAAAGCCAACGGCAGCACCGNCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCA
+
$*(('*!!++#*+%"+)%'&'%'$+%**"$(!)!+)*!)#!)+#*!"+)"#*%*%%"(&()*""#"$$'%*!!#$&!+*'+""'+%%%'+&%"*%%$+#*+"$$#&'++%+&"!#($&!$#%$$!#'"$%('*+)*((%'+!%+#+")+$)&$%'"&((&!&''#)*!((("$%"*)&#'%"*)&!**"*)'*"!+)(!(
@r7512
CCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCNGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAA
+
40>$1B7#69A0=?(>A%@2?-E$<EF)F!=)49C"?67!95#731?8:-A?"6"(F675+;#;:,5AF-2>;%:96DB7B8&?1-!!F?8@'B)'A'63$1@H*<"
@r7513
CGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTAT
+
8=1;$8$;=+<FCB.'+C/3?4;!.2F$F;6"#/2(F(GEA(B+05%&G@;)5=5!?)>&>F$<G?C$)5AE$&D@(=?@,C$,->?(7.,&9>(&>*H7;D@G@4'0B51711C;@7C+%"6<6@A8E70.9-(A$$-CH<)2'7-H28*7E6>E?/%"7"E3//H!*##21B16>2=9;!?6HA&0'9>3#$:A7+C*>3;E76E028'9A8(+8-@E28"HG37C6'@7(/05@B>A&H.1>7,
@r7514
NNCTGACTCCNGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCA
+
$%E@(!/;19?E+G,718/*,:>-?B<76'?/8("4>,HF1"E-:/>*/AD<20
@r7515
CGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACCGGGCGA
+
<;@3A:A<"=:/:9<)?&>&A0/808/**7)1G&=10A0D0)#2F".,?<@%)EEEC*>0$%"8A?-8(6&G1"E<@2B?>&E7A3%0HB
@r7516
GAGGGGGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTG
+
+%*!"#%"&#&$+)$"))!)!%+")$')#())$")))$*%#)*"$#)%)')&&(*"$&")%+&"'*$$!#$+&)*()&!&+'&#$'$)*%+)$)$'!($)*%&*))*+
@r7517
NNNNGNNNATGANCNACGGGCAAAACGCAGGGCCGCCATTGATGCGAAAAGCCGGGGGCTGA
+
"%"!&(#)($"'#*!*+#$$!+!##&$)%+%"&%+*'+)!(+"%)++!''&)&$+'"(#'*(
@r7518
AGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGTCG
+
8#:96D?2C#:(F6H)1&340'?:"!,@DD#343@<(H6$HA998
@r7519
AGTNATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAA
+
)#"+*$&&%#*'&!$&)%&(!$('#!!#'!!#*!#$%!#$'
@r7520
CGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGC
+
-,?G)@0#HG<)-,+%>4-FE6B"D(<GG>!.68H!2&>0#
@r7521
TCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGC
+
1-D#A(13$21H!7@*9F<?G*>:9*B.:/-9619(B4';CEEDF('A0,E;0*DC'?)%2;
@r7522
ACTTNATAGAGCATAAGCAGCGCAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTGAGCCGACTATT
+
2+B".61=-4HB>$<B8E710'A$E@'=76B-#.5=/(A-@C!.D"E#!5%E=)8HE<+9@#E%+4;4$/>?GC>=;.57)A:'B&'/0-3/*!4
@r7523
GNACGCTGGTCAGCCGNACGCGGGCGCTGCAGCCGNACTCGGGGATGACCGGTTACAACGGCATCATCGCCTGTCTGCAACAGGCTGCCAGCGATCCGATGGTGG
+
(!+%%!&$'+'(&!'!&$+&""%')%(+$+$(!")&*+$$+(""&*+)$*+*'#*%!&%+&&!#+(&&""&+!&%")#&)(#&$!!$($$&#)$%(#))"$#$(#
@r7524
GAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTT
+
4A5"A)FB<5)=6!E34&:8#CH,%!!BHE%;)(+G0>=EB%=:=0,C3&)+9H=5+0":E=153F@.20B?D:@.B>@;7#(E!>F%#676H*BD(%;2%C$'>":D;.?'2%H2GG9.,6E
@r7525
CTGCACAAAACATATAGATGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTT
+
32F5B=G9$/@9;3?<GE$=9#A!89**%)<5$@0%,-9A:H)0'1?2E@9D65<E+.9(F8$H!F/19(
@r7526
CGGGTTCTGGCTTTTCGGGAANACGGGATCACCACGATGGAACAGGTTNACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCGA
+
)+*)+'#"*))%$%'"$*"$$"((#$&+'&'$%"*'%"(*+$%'#!##%'#"$)"*#*%!*#)!()&)+%%(!&&!%$$"$(+$
@r7527
ACTACACAAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAAT
+
>+(@%9;89#"+;=D.)A=?(6+-(:025BG-:2,D2),/H0;.=?)FF$D6BD9E!=E6)7DF*7<<8$0'<=E5#(
@r7528
NTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTT
+
($,EG37A>0,A*A;=.$HH3G0+?/20?@4+%.?!'2%C'2=',07G)&(6=><2"?=)#6:'93><?3/$*;<3*%?*G;=0-9(9
@r7529
TCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGTCTCTGGAANCATTCAGAGCAATTGAGGCAGCGTTGGTGAAGCACGATAATAATANGAAGGATTATTCCCTGGTGGTTGACTGAGCACCATAACTGCTAATCATTCAAACTATTTAGTCTNTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAAC
+
E@#2!2:,D$*?0<'G7+,H9$'CBF!(21G7+5G0$.4$5D68E+A702C.H2)09:(;4A9*DEG-!)8?FA1BC3=9&;G)=)?27<:!8)'<,?6:2#&66"8#*(5"1://1-.504?#G'/10;1,+#8$6-+20100)/'+<!.0@+,;FH87;1>-(F/?.!?F$"#2$8HF872+>6%54!8-C,.)*/$/#FC<609D<<3'!F&%%FD9GB7C#$9G,<)4/-5AA=;.15<!>*0
@r7530
AGTCGATTTCNNGCTNCTGNTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAA
+
'(%&&$(!'("#"#'#(&%!)+'(*)&%!)&$%+)&")"$('!'&+)$%))*$*#$'*&)&&#"#$)%%&#"$%'&#&!!!%+(&"&)!(!)'#*+'!$$
@r7531
ATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCTACGAAGTCCGTGGCTATCTATCGGCTTATNAGTACTTGA
+
+++'#"('!%)&'(+&$+%!")'#!)+$*)%*%%#$('+"*""%&*$#("!'*()*'"+!'!%(&))*+))+*))()'"
@r7532
GGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAA
+
"(*+)#'&%!#"#)+*$$!!($"&!#($&$)(&&*$+(*(*$&!++)%$$)&!#%+%#+&''#'&&+"&)#%+)%*$'&
@r7533
ACACCGGGGNGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCNGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATT
+
7&7<*;,5@62D;F$$F-(+A,E0?%+7E'0F%AB/)F#H@0+F@,"&:71<43E#;@3#9F)8G2<%#D7&9?E=C&GDF&:01'0!%9=<%7$'"D8>(7$$3,C->>3>9=;B<'<A/>D=G7*!;<<(41'+;F,2*9<,)!4*>D7E>5?H0*&./0%?@;-1(?(
@r7534
TAACAGAAANGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGTTTGCGCCTACCCGGATATTATCGTGAGGATGCGNCNT
+
)5A186.A+!$A'7D$;143%F$9%-B@!EBGD:;8BB,D&4!AADEC7?<:+!=5,*2+:F238"F;CB61B:H;7>3#'9"5(-"$!#.B<9
@r7535
TGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTNTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCCGGAGGATTCAAATCCCTCCGGCGGAG
+
)*&(!&++)%+'*&%$$!!&+&'""'*(+(#&%'+$")"#('+"*))!"(%+!$#!#''#()+%&&$!("+))!$)+*'(#"+%+*+%$*&*$&&*&'$!"!!($$#+**&"!!(%()!&$$#!'%&#)+#*'#*)*'+%+&'*"%)&"+)))#+++++#!"*%$&##)+#*+!!)*%"$"&*)#(*'$&)&!"!+)&*'$*('(#(**("+"#!+&!&%*()*$*')%++%#+
@r7536
GTAAATCNGCGTGATTTCCNCACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCCGGGAGGCGGCACTGGCAAGCAACTGACCTGCACTGCAGTT
+
C-*<+#E>3/176(:9#<42#5.6,%<0,=;%,&.053<B;4@G,.3/=(4<H;'%CG9<$A9<"78D(4,93.7F>H,D;-;.4.,%:"CB7.E-83(?92*'G-&:;E31E-E%(H7G!A7%+A,84B@"!=6+-!)+*;480E$?<H
@r7537
CANGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATTGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCG
+
G1$-"B?H*"=3C13-67F/(<("2A5.%6'D921,2-BG)%?!#81775A/)!EB'@(D-D'#EF698+1)@4$!.&3<'2/C9(FG##&H$(+6=)B'7ED?,F*>+=*-+1G/G0+GH6#C)?+74+@+G:'?,>$"1#(=(C:;5&=/;<11:B9(&613/$"0FA..7)93%G
@r7538
GGCCAGCTAGGGATCAGCAGCCTGACGGATGCGGTNTCCGCCGANAGCCTGACTGCCCAGGAGGCCCTCGCGACGCTGGCATTATCCGGTGATGATGACGGACCACGAC
+
%?>AC7E46:C7</C9&E4(,'B=/->#7,(1H%G@17#@><A:,$"5+H.,2H'E4)B8".$7E!8%'<%1D5(567<069/D/49G1#6?2A%'.$(H6C7G-1D#;
@r7539
TGAGGCGGAATATATGCGTCACCTTCGCCAATAAATTCATTAGTTCCGGCCAGCAGATTATAAATTT
+
'977282&HD8&@D90(CED=93=&.H87A(D2=#4.7H/94+4):1><-"89?<2+F"><@?17A7
@r7540
CTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTGGTGCTGGATACCGAGGCTGCAGTGTACAGC
+
H:59+.#9%(*CF72#<=DB"*FGC=,9'D--!32%#;?('2B&A2+C!#?%E2%/BC0&)86?1:%6&78@.-B)G'B)B:E5)72D<)4/A)>/2CA0&?:=!&#8-9,*HF*704/1)-6"F0(*2)'<
@r7541
CCAGAATGCCAGCAGGACCGCACTTTGTTACGNAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAA
+
:3!>E='A-8,1H'(B426*'5FDH=341D0+'<&+-)-)B/7/3+9C4.:6'6.!7C+?4!<'C9-E0#1B(+936G>$9FC&4(@
@r7542
TTCCNGNAGANNNCNNNNGNNTTGGNTNNATCNGNNAGNTTTGATATNNNCTGNNNNNATG
+
"$$$###$!#!!!#"!#!#"#"!##!!""###$!!!$""!#""$!#$$!##"$#!"!$"!!
@r7543
NCTCAAAANGAAGTNNGNCNCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGNGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGCTTCTACTGGTATTGNCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCGATNTCGATACTCGTTCTTAACTCAACAG
+
$$$(*"!"!()##"()*"#%$'+#((**"#)%"$'&'!+$$$'*'(!%"))"("'(*!(!'#(&+)("&)#$("")#')'#%!%'*#&*()*#&"%#$+'$"'('!"%+#&$$!*&%+'*+!('%"%)$)'+(%!'$!'##**&$'*(''$$##"+*))+*!*)%&+)#+%+&++!+(#*"!&#*'('&$#+)#$+'"!+#%$+)*'(('%)$)#'%#%!
@r7544
NATACCGGCGCAGTGTTCTGCGGAAACCTAACATTGATTCAGG
+
%G7/6+/4E=C?B6D,CBD?4@979E'F.9,@-+/),GD@<2:
@r7545
TCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCA
+
"<D=)%F+7@79.*&%/E$)$F?B?ACAD;=)11A0592:<61.7%*"(560,=%(0DE
@r7546
NTCGTTGACCCTGAGCAGGCTGTTGAGCCAGGTGATTTCTGCATAGCC
+
)+$*""(%*(+()$#")''++*#*($"#(&#''#&$!#+*$%$!)!'%
@r7547
GGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATTGACG
+
%E&E0&)-G490B4<@>;*79G1?AE=)57D;8&#&%&G&1B-*@C3<-63>";G>:)G1F5E2:,%;H!G;=0:(F.)0$AD%@-'@,;;5A
@r7548
TTTCACTAATGGGCGTGGCTTCTGGTGCCTGNGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGNTGATATTGAACAGGAAGGCTCTCCGACGTTCCTGGGTGACAAGCGTATTGAAGGCTCGGTCTGGCCAAAG
+
A%!66<;+*&0)>06201&.3!>.F:*7.#@5B+#;!E)=:856:D*@@#A2%;A1;?5=98<4E,93*,9=*$./83-!>8&+44/5D6/499=?E272"#,7,-$5*FG'9B)9>5E2.#%:86$:'8G32=*C"A?=!':=05<03F?E=F8AF5H4DD487%=$?<<()77F:&
@r7549
GCAGTGCAGGTCAGTTGCTTGCCAGTGCCGNNTCCCGGCGTCTGGNCACNCAGACCGCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACNGTAATTAC
+
D145=HG?88@#!+;$;?2&C1?B9@;A0=/0=;"4$5<0.B13C,>6FAG<1F+F-%CA"A8)EC61B-?.@<21&,DAG:#=",)$<C@E(07&H>#%>
@r7550
GTTAGCTTTGGTTGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATTGGCACATTGGCAGCTAATCCGGANTCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTNAATTTTTAAGAGCGTCACCTTCATGGTGG
+
2-#.</3=<?+HA9>;6/$B99,6&/@:A4#C>EG3=.$>%#C-A8E5;E#-7!?25/1=ACG4(9-(7/3181/.,),,/@6A"</$02+,94@G4+(DA9:6;-819C6"D6B2"%8B<"&;6,#8&'G1B9#&,%"G#&<>32>,H%#:$G6$%C%?*=@H=G!9(?-#>BCA<'$8.DG/+@EE
@r7551
GAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGC
+
+='37,C3B,!(0(2D9!6/GE&G7@=:25F!"3!3G2F0>1<!5@@#DH@C/;G*&))E:;AB59
@r7552
ATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAAT
+
8<#BC43%>,G4+/<5F$+B."?HB=B,4!!$)>#1-<!7=E$#.A&?-B
@r7553
GAGGNTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGGGATATGTCAAGCCGAAGCATGNAGTGAATCCGCAGATGACCCTGCGNCGCCTGCCGNATGAAGATCCGCAGAATCTGGCGGACCCGGCTNACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGA
+
6CHH,$;?C:2/9H2!70EA0/#3(<&26BC:H:-H@0$7#,6C#2!!:(5=9'9?D##H=+2)#;7AF2CA'<.=7)>+C*70('+6>C(1)!03)=87>$#?$&<@;1=!H;<C':-G<%..$0BF484>D,=:=E,C+,*5/+2-5;6(9593>)F!,20(/'-63GFA(18F/=1*D&&/$>6B;A+,3,A'/3"849"E/
@r7554
CATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGAAGCTGACCACAGACCCTACGTCGGGGCTGACGGCGATGGCTCGCCAGTTCCATATCG
+
1'F(0;E'+!5.7A.9188)%E55<B$.EGFD,%D$GF6@5'?.,%7-A$&BB.();"&"<<&51'#'<D85=/-480+*8=>A$.(H8/(?000H5.!
@r7555
TGAACTGATACCGGGGTTGCTGAGTGAATATATCGAACAGTCAGGTTAACANGCTNCGGCATTTTGGCCGCGCCGGGCTTCGCTCACTG
+
:/7,0'/H+%*0>CHF>(4D"3A*:D!164/E'.:>#80"6<F0&63D#//9'>"*F33A-D@*F)7C"=@%&H"/E>H'G0&/22D(:
@r7556
NTTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACNTGGTACA
+
.'E2:70F.++F/*+D5-+,09>*1=(,%=3>6+5H=2!*G6FB;:2<(9<F
@r7557
GCACACCNCCCGGACAGGCTCCATCGGCGTCATTATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGTGTGG
+
7!-+5GE+>6@=$<6=#)79-:B">=:"*4#H+CF!$3>5B)9/.F@D<%1B=1F'36#793=06&/'4$E2!2%@-#>)
@r7558
NAGTGTTCGACAGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGNGACCCGACTGGCGTNCCATGCTTGCCGGG
+
!)$+!%)(&)+%#"%()*+#+#$($&+$'!$*)('#!)#+(#(%&+%%&%&!(#"%!&+(*#'*+&!*+)+(#"*''+!#'"'
@r7559
CCTTTCACCACCGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGA
+
4(4?7.H4<>A>)=E3$-<%:$A&'/8=3@.&3!#=0GE!1'8C86=.:$1<*9-887H4GA:G"4*9G30)3&$'D'(2
@r7560
ACAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCT
+
%>0#!E0*%%$58382E%$"A,E,2&61A7HE)F!3*A2'6$C?+'(!;<F#&<*B6>DH9C66D72G
@r7561
ACAGAAAGGATTTCCAGCCCCCGTGCTCTTCCAGAAACGACTCCAGTACCG
+
/2>=$5H"@(6D2'4;2%?6F<)G9#7:GC42!9=0>@(65797/=$6F#%
@r7562
GAAGACAGTGCTCATGCTGCCCTGCTGACGCTTCAGGCAGAACGCCGGACGCTGGAGAAGCNTGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCNGGGATTTGTGGAAGGCGGAGAGTCAG
+
0,%4)A357H1/6/6?&(4)!?($/!!(%/9/-?:(#8+*7<238!@%%70';.5&=<;E)<-@0>F0?)22&54*"@AD;;'=17G2@F?.!"G!(:#@%/+"0,3H,DA;=#G()$"847-
@r7563
CAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACA
+
?@93@>@;"@A3G8<-:+)?B#&1?:$"*F>(E5+EC4F?'88
@r7564
TGCCGCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGAGGATNCCGTTGACGCACT
+
<0.&D7,25(:2E3E9%@&>+C,#/?4/5)A?17&220<&7%$+6/<689':9'-E1B0143?6+2&F.1#!@92E-,
@r7565
GGNACTCGCGANGCTGGCNTTGTCCGGTGATGATGACGGACCACGACAGGCCCGCAGTTNTCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGG
+
1?2=!4%E<H()E8G/A.B>)G55/D<726346G)+6?C77D#;.*%$;"+*G%8:2'!33"2!34CB3;G<H*01H+541!<BE,+H:CH6D=D@"#$1:DFHDF-
@r7566
TTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGA
+
,A>09>$+2'+!24,@?GC6@/3>"&0:B);.0732%6A<@/B!*C.0>"?G
@r7567
GCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTG
+
A.;=#E<?<)CA3+:E(A6G::<A?60F/;HF=@38?)G/6<9C$%*,5@H-@;.)2$=D14*?2>8@"/"+.'B6A;E#"2.?9=*22%)7/?#,$/8345076C&><&13<1CF.3@H02!8=EA'*!/%33%FGG3F&=C"23%&D80!.60&43E-.7"$#B@&)AF5E?HC*D6'*G+&D%"/F
@r7568
CGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACAACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTG
+
-%.G22D;/+>HE?,6C690"1%&09:C!#G4<"<8+0,(#>$0&,1@4=/8*.$.1(0B=;2A6(H9BC'0H.=97G
@r7569
AGAACGTCGTTGNCGATGGCGTGCATTTTCCCGTCTTTACCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGTCTGCGTGCTACTTCTGTCTGATTTC
+
@FDD8.)?9>.<9F!A8"'7;9./4?</3;@="8=<"!D,5&=-31)&E<,</;&+-0)9=?5:78-B8*-<6A<7-92>%2$:"9E'D7@.C@C76%677H&0#?
@r7570
NTGAGNNNGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCNGCGTGATGATGNTGCCG
+
)*'%)$""+'+%""(!(!+$#&*)$"'*)+!&#*#$&#)!+'!&#'"*"(*(%#!#$%$%&)("*(#$'!('"'++*&")#)$'*(%
@r7571
GTGGTATGGCAAAAAGCACCGNGATAACACGCTCACCATGAAGCGTTTCAC
+
28#.@1+0C.15.;*7E'DE=0-'2B=<7<C#@@9:2+#*8C7/>,)-$D7
@r7572
AAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCT
+
CD*DF,'/0/B3&25#:A,FH)H2#@=&4001(7*=#=:@,+%>#%385G=/9($/>4#94%$-'>@F/:<-67F1810;B+D56D
@r7573
GCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCNCTGNTGCG
+
'+%%!#*$!$(!)$"$)&$$"*&*!%*#(&)$!")+$(#(#%((&$*'!'%
@r7574
TTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTANTAAACTCAATGTC
+
/H?$#9)1*:*+0=E;?-2>6%'GEG9/=%H(*HFA'%)>G/B%.<F-6?:A/286)6D<@)4G":..5*B.#<&6!;1396.4FF,G5;%
@r7575
ACTNTGTGATNTATNGNNNNATCNNCNGNNCNCGTNATCGNAANNCN
+
"$$!###!!##$$$!$"#"!"$!"$"##!#"$"##!#"!$!#"!$!!
@r7576
TGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGNAGACGAGGATATTGCGCTAACAGNAGGGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACNAGCAGCGTGAGTATTACGAAGGTGTTATCCCGAATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGANGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCA
+
5D6/57-36,9-:1?E8>/4-(82)*43;(8@''4*48/76&)'+$3'"?)?A<;,"<$>2?!'>5@,#++B+-3A!#G=1)-/8:3=;CH36;4:9//2%B18#F"D3%1+$C5'$:B4:-1B*1",=5>CB&#:E<;&<-F:HD41.%@&'.,58/=(.*23:1<2#<*H65@+!@A/H!)4-CD3+.=?=#1=(2>F#4;$28-9G36'C;*4#:*8&3H>>&%CAD%8>65A8?;<+D'>&:9"#,$&0'3$A82
@r7577
TATTACAACCCCTACAGTTTGATGNGTATAGAAATGGATCCACTCGTTATTCTCGGACGAGTGTTCAGNAATGAACCTCTGGAGAGAACCATGT
+
1$1@5@)E<)E/#=7D:G@+4B#)9&D1:5)'G:78<H4##%AC<.>*A8A.F+2,((CC,1EA"#4<:G@F!1%G4$74E%1GA<)6:%-9>A
@r7578
AACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTGCCGCCGTCATAAAATGGTATGCNGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGCCGGNAGGTTGAAGAACTCCGGCAGGCCAGCGAGGCAGA
+
##H!(E&GC!C1&;6F<%9H?$>/6:8@5F;4.E49#04;;/>3'7>D@.G:F:-)9$!/=*>9#.#@3=>0.$/F105&')D%.@*6,'?$).*4,G)E&:G<922B&544,:?("$!0?C39>&)&7/=@6B?3A>@&'>&:D>D*185/<0-=-0>::G)76
@r7579
AAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGG
+
B%F(0FG..F%/"!?:978=0?"-&.3'!-5H12E3%>64!C
@r7580
GACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTT
+
30B95CF</!=%><ED,47?1D&/:.&H6-A7(%C-'(-5=63?$
@r7581
GTTTCGAGGCCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATG
+
GA@82!G08891>H'-:7)-=F-FA1$(B=5)?..?::.>'#+?6G9/*=
@r7582
NATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGCAGCTTCGCCCGTTCCGTGCTGTC
+
!)(FF0"$.:F32=-?72)C8?%"79F183D;!+68%/'$)EE4,?6H-#>D!)HG+C/9>>.,0.(-/4%?0DE#7/":
@r7583
TGAGCAGGAAGTGCTTACCACCTGTCCCACGGAGGCAATTTCTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGTATGTATGANTTTGTGGTGAATAATGCCCCT
+
1+D/5C=&8=!&&#A17-%1==?E<>=65)+#;B$8)3@='.FD4=;+4+$(>G<1!(A31.1/!?9C-0?.A71;H9$H3C-!A:!5-H(.F!B9/B?<EH8377
@r7584
TCATTACTGGATCTATCAACAGGAGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGAGGTAACTTTGCCGGACAGGAGCGTAATTTGGCAGATCTCGATGATGGNTACGCCAGACTATCAAATATGCTGCTNGAGGCTTATTCGGGCGCAGATCTGACCAAGNGACAGTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAATGGACAGAATCACCGATTCTCAACTTAGCGA
+
%2!*(98H5(%6;<(1":;059*:H"6?7:,&$4/3:F$2,9&67*9EH7A:B&:4A'(<C:8*=H@G6C3#@#;=8*;/B'$:?E;'D"+F&1A3.>E5'"H@1+%D-2*-/9?"DG":,,*!@0+&&$?A'35+9:)F68FE;76%6&1<A"9"1G+0)1<F5?@:;##C&#.4*(3G>4"#.9$6'7:GG:5@812#>3*:)F?+:E,F9GG374AA;6%-B7"&C5?58?6#B.,06$*E2D?1>A<EF8H-,76<
@r7585
CAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGTCTGCCAGTTCTGCCTCT
+
4?,F?HBF"(4*D%4)H(,2&3(B>%&F@1!E@,?(!%";36=@=$$;DC9&H
@r7586
NCGGAGTCAGACAGCAACCGGAAGTTTACTGTGGAAGACGCCATCAGAACNGGCGCGTTTCTGGTGGCTATGTCCCTGTGGCATAACCATCCGCAGAAGACG
+
!??CF-+?(010E/G)A+$:05*..32+D<:$,8?.6("8A&4/GA>6C//@>B)8545(6/:#1F<0!0041-/3<0%/*"1>7+:"GH@/(F?AC<,!5'
@r7587
ATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTTGCGGTATGAGCCGGGTCACTGTTGCCCTGCGGCTGGTAATGG
+
@0)3./%H6@$3%9:+-CBD3)#/E8(B*+7#1<39"01)E>>2CB2?)=E1F3A5-2&+9FA#!4$&0C:1.11%8%9/7
@r7588
CATCACGCATGACGGTGATCGCATCGNTGCTGTTAACAAGTTCATCAGCCAGTCCGGCATNAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCCGGTATATGCCGACACCTTCTGCGCAAACATCTGGCNGCTTGCGTCCATCCGGGACTGCAGTGTCTCCCGGACGTCATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTNANGGCTGCCGCTGTAAANCAGCGTGATTTTCACACCCTGTTTCTCC
+
D,;C)CH62+?(>?31D!,@:+*%%#/H9>769B,'#5H,"*<!6G;-&)/=0>&?E!!6FA/7;>CH5E"H%+=GF<5!BF8-,7335+633>/:+!=F'&)AB!3,1/7?=?6?D<<=-;1!:0AH2'60'4H+'(E:0+9C$B4&A7<502H/1<5H>AH5>$$G9#190@C=#'1/58@52*H1:6@0G.&$0BA#E@)4DF"5?3A1?,;1325*/2?;*7>-F2?C2'0H)1;+4">=5E<(CEA<3=B6%0&;"#A?/&0,C>&(>";>)9&5H
@r7589
NTTGCTGTATGCCGGTTTAAACGTTCCGTCCCAGATACCGCTGTATTGCCGCGTCTGCGGGTT
+
&G+;5CFH5.7$@"B4G5,'.E1.G9>#.#18%8:18:"70>./0DH@H**-)56B2<C7/+'
@r7590
GTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTG
+
<?;=C.-A/<C1+75HCA.D,D#3H2G'&)C-72*'@!2.<4A6748?$.2@A%60)"D1DC/526$017AA5<
@r7591
GCGGCGTGACANCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCATGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATAC
+
=8A1/==:E#&,F200+"5B!#/578<=*1#086!#8$$>-*;CB@:3(@86<(G:<?+;8=&4%<5H3C&C;&$.6=..,2:@D-2?$BD.&B735+-(.H4&$E4
@r7592
AGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAATAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGATAATCATCACCTGCAGGTT
+
5/13<!"4<3#"'@)1("3A**AD81(,<2883"?;.1H>'G?","<+7",CH%#5,!2=2D7#=+/*'>37:'0/-.3%!/#%#@2!.#1H8##0$78!"$2G+6>9D/!6<58&HF(9+0H%',?F"CD?++=4G!80E;()6:+;>H;%)A8D,F05,7%*/$58<G>B"$9?.)'FD=$F3**BB93CB9A"5;B/$#;/''0)09*$"$+9398/AA:D$F!3.E)#1?10$C?'8,+
@r7593
TCAAAAAACGCGGCGGCCACCAGTGCNGNTGCGGGGAAAAGGTCAGAAACGAATGCTGCAGCGTCACAACAATCA
+
27>>?GB/3"@,$E$3+1?:7;";'>22=C!7"G3%=9@'(G1B.GE'D+$*D''6:/#<?*%HF7;5:+0+'%9
@r7594
TTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTG
+
$CCB$9(G9*F0#B1?&3/D95G7+=A'-0A/=77B;>$98),@,%=);8'
@r7595
GATGAAAGTCCGGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTG
+
1@?'>.6(+(>5EG>B>@&')<$+G;*(H*=+6A:.3H$G40,$",D6#&6=+%?,
@r7596
ACCCTGNGTGCTGGTTCCTTTAACTGTGGAAAAACTTCCTGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCAT
+
:C6+:*/.C2,E:7<,7'38$<F2)2=&7,4<"9@(H:<AH%%,9))F*,:B,%C;!=;)1(!?8"9)#>$1/=F7>)2'15(F
@r7597
AGCGTGGCGTNAAGTGGTCAGACGAAGCGAGACTGGCTCTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAA
+
C48G?/)2948D.(:((9/A5?@3!'#19D'2'-?(1#G4'=60C7D/>E+,&6@5C9A"(EA*3@?3+E,:#2GB<183@
@r7598
GCGTGGCTTCTGGTGCCTAGGCGGTAAAGCGGCAAAAAACTACCGTGAAAA
+
:5?317#!.9<C3300!(+%)A:0&$,=BA6D03?C!0D.AB&AF=4EBA+
@r7599
TGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCT
+
9B*".>'9#(2A4E?68?C&EA91)B("H4G.*A:%!-<&<5D
@r7600
CTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTTCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAA
+
C/;H1#)=DC,?"?3-$)G4.7.(#6"H#:G?;-/,BC09?H:8%&<2A'A!28.$+3B;B1$8"C:!<0>E#'-:4,*1>8(!-/43(65>/*$!+67%%/9!GF5*E#>0H*="&BH2C"'9&%1%"8%/-;H.6*!+43;A&(2#7)-?F)/0#8EH6./:74:120>.37.*
@r7601
TTCGCCGTCACTGCCTTACCGATACTGCGGACCCAGCCACGGAACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATCAAACCACGCCAGCAGCGCCTGCTGCCCCT
+
41*3E"4/<@/,5.)2D"/%-:=9G:(!B!8'=F78/"3'@)?G6A)5A8FFH-.!C8;-;:":<.*C$ED9H:/.F@AGDCA59D>F;55@52B$@4D+H;!A770&9&H4*,?"%&@F/@!D'3F(+B
@r7602
AGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCT
+
<68<9%<!@*1F-C(A,:C)>,D;@%B5<&H#=*$%.#4&8,9@G/)76=(F
@r7603
ATGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAANCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTNTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGC
+
)(6>G0D(+)<"GHB(51132!'64,?/"B4$1G,5:$+0*(2*D242HD:8%&F7A2%A%<=<6&+7(3%=B1C;A2!3.549E?$3:4&/D<C;%:'04(?*/2@?"=76+6<(">:2#D*32.
@r7604
ATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAANTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCGGAGTTTGCTNGGCACTGATACATAACTCTTTTCCAATAATTGGGGAACTCATTNAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCG
+
3#042CC'H2DGB-E1&,;)B%.;'A7).<6D=0A01>FG1G+)8EG=F+@=;!=*BA7@5/0!1;/?$,>/77@()9":=""&=2.,*23(0!%(9H(;+<$3F-A&@*8D"*E=1"?5-=+C(4#8*>E)7<(<):HE*H$&+735!8%1C."505F>H;H!9A/AF?<C")/!&6-EH%D@G19)'2BH+4#H(2:(
@r7605
GNNATACCAACATATCCGGTGTCACGGTGGTGTTCCGGGCTCGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCTTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAAATATGAAACGCCGNTCACCCGCACCATTACGTCTGCAAACATCGNCCGTCTGCGCTTTACCTTCG
+
&&"+"'($"'""&'#+)!(%#$+"!(%)")"'!#'+"(%$+&+!"')+"+$$#"(*'+!*%"#($""!+'#&'+"(!+"!*$')!$&+!#+&)")')%&+"#+!!+!!&!"(!$'$((##%''%%(!%"&'"(#%#(#''%#&!*$"+)"""*)(&)'%**)!)*%")!*'%'**$%'$+
@r7606
GCCGTACTGGTTGGCAACGATCAGNAATGCGATGAACTGCGCA
+
D,A"E@"'/<!"%<GG/G61/,#F!.'GE=%A5?A0BA>7<"8
@r7607
CTGCTGGTTCAGATACAACGTAACGGTGGCTGGGTGACGNAAAAAGACATC
+
3*%<;!*4F/<$4;'&66!>$93%7;D5*FF=<,16C8+3E="()+9)0#G
@r7608
CAACCAAATCGCCCACCGAGATAAGCAGGTCTTTTTTGTTGTCGAATCCAATCG
+
/=H>0';%/9560(!'ECF7-#7,B"=>>?&E8B>=%+B<%!4?.3>-1G-%9*
@r7609
CACTTATCACTGGCATCCTTCCACTCTTTCGANAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAGCTCGACTTTTTTCAGCAGCTCNTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAA
+
-H"@D<:;@286"6CB,:4#6:HE!H-&2A%'C@?#1<D(%B;8,%!3&C%AD?E+1%&,,A3>(%5D,%H9H6&7'41*;+FA%7':4*EB:=5EA02""A:G77E#).,B,E2!/9.433B;A?@F,!/6$!5'3.
@r7610
CCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGAC
+
C1D,"A25;:#;D.8E$05&,G2BCHD/824<.%..))>+*9=-28(CC"+54D?2A;
@r7611
CNNGCATCNGNNNGACACNGCCGTTGACNANANTNGCACCGAGAGAAAACAGGACGCCGGTCATACCACCGGCCCCNATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTANAGAATGATCCNGCAATGGCGGCAGCCCNCAGGACAATCTGGAATACGCCACCTGACTT
+
*"$(#$)(!&''!%)*%*!!%(("('('#&()#("+'*%!(#'+*(&*&%+'#*#*#(''**"+%!(+%('*+$'#(#+$'$(%#*&+$($*!&+)"'("$!*%%'%")"%+!%!%)%*)*'*()"'%+*!"'')#+"+%)(!$!#+*!($'*%!("*)+)!$&()#&#!"(*&&
@r7612
GACNAACTGCGTAATCGGTAGTAAGCGCCNCCTCTTTTCATCTCAC
+
?;&&;BF&9@@)G$6H38:;:@87"?$%E)"3"B>;H=D3F1>;C=
@r7613
CACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTC
+
HH0'-7@!!)3+*C*<!36#=EB)$9+/3.!075,E.@"2F);(5#"H#9F&(,1G5'?
@r7614
TTTGGAATAACCGACACGGGCAGACTTCACCACATTCANCTCACGGATGTAGTCGCTGCCCATCG
+
6)#A91.#%($!/%F+"7H3G-+&6,-0:+G1"D'$56'%028:'6$@:/9B*9?525-/1"4-6
@r7615
TCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTTCGCCAG
+
>E&,B+:.#:=&5@)59A&>:50?G;$,F"<=$83G@&=F)(!B0.)%8.3$G?D<F!?156<02/C"H!G'%B+G-5E@'/+
@r7616
GGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCTGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTTACTCGATTGGTTCGCTTATCAAACGCTNCGCTGCTAAAAAAGCCGGAGTAGAAGATGGTAGAANTCA
+
)(<=9(G/"$:;DH/8<DH3D4.3F%@4.1E;H=7=47:%-,+*>2F3,B')/)/75>53;D5'/5?*<1"BH@?"&H.%F3.1<>!B<E38&#2/4G',B*DDHA-9&FE:&+)).ED1'=0&150&-<+9'A>"!&20A';)(*+27C+,F*>/9A+/#"E-%23G7C@")''+2F73""(,@+?2E-@&=.;$@4H=E*>H-6D-@%=&*AC&EB;AA*44.?)B?44;1H'G'$'B19!=8?D.B@'>/'F6.6144/D*41H1#16H171.
@r7617
ANTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAACATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAANCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCATAGGTTTTACGCAGAATGGCAAGCATCNCTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTACCACATTACGCTCCTGTNCGGCAAAGTTACCT
+
!&78#03B/94@CE49437&5'80?;6'&H;.499+!F=;25*B=*A%&)C88@"H0=%C!&8&):&4,12*+:=AH73<B1G:>*!)7F:D&(C:*-3*F=0:/.6!5@>&?>G;,)%40(,&C4?76=;6.&*08E;>5-2'+.@D>*<0.2%HE9#5.'))=E10B)=0>=,.%</4$/4G,G-DG)B7>-ACH<!/*H255G500)'66''GA#,G',.>8"D3E98/D;,&FFA!B0!2+07'6=<*&+;FB.4*C,+<F3)DB+)DHA"('A:7HB#:(623'&CH?%=A)3./)11)<4E*)C8</6B"B97*F@)"<>-@.;&2).&/0)5#3//>BD?@8A69;?1*=B.>.#1:6(:
@r7618
GGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAANAATCCGCAGGCCAGAATCAAAGTTAACCGNGGGGATTTGCCCGTAATCAAGATGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAAAAAGGGGCAGCGTTCNTCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTA
+
+&!&+#&##"((*!)!!$(&)*&!')+%"))()(")%($))#*!$)#*+!$"*&"'#+$##+!&'!+$''($)(%$!+%*+!+*%&)(*!(&%#!&'(%)!*(()%&$(&($#!&"!+$)#&*'$%+$!$'"+!!)'!''%#(!&+#")'%(!!**+&*$&"+!'%#'%!$+($&"#(+(!*+&(&(&#''
@r7619
TCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACNACCGCAA
+
;*72@2.8=70F0*5$=E9(&+=*C(B;'4DH-@<=4;C#!+>.>C4/#;BDE8@,9'@9E+E5#.;*@;55>3
@r7620
CAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTNTTAAACCGC
+
E.*>F'3:7G0"B,C<;&/?%$504F)G6->7AD(84*)9H=!G<H
@r7621
CTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGC
+
=*$$07<+,(G4B%.B4,,)0;8(-G15/'3#3?,,C8?C4:88;+G5D<7F/E67"6AHCH:2FA@726+%%(%H32CBEE2102H3B5E'@2%#D=?4&1><F@+
@r7622
GAGTAGTATTNAACTTAACGGGGCNTCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATNAATGCATATATAGTATCGCCGAACGAT
+
"@")?),?+G;D@)A;5(4>%&">"A)HH49!E)/4/784)9!(3FF,B"78.17#>>FG;=A@1EE69>>B<=-)EC%#5%,.A;+HC.4+A*H-'&C16H?'%+/+3(E8C9;88(2$()$&=6/A:8"<):(C=)/@%/6E6&%"+?(:H2
@r7623
TCCAAGCCAGANATGACAACTTCCGCCATAATCCGGCGAAACCCGATCTACCCAGAAATTTTCTTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCA
+
C2C*>.;H6;A38@69!1&$:$0(?0#8<#%F7+,,(.'(63@-/+8&.0BG<AE9.?14"-%*2:622E>7F@3022EH7DH2.C"#>*!>*-*??$9!?@7,H5,AH=:+)A(<<83.864@FH,!=>;A:(3D=$BB(<#A7
@r7624
TNTATCNNACTCAGTGCGCNNTCTANNTTCGTNGNTNCGGTATGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTNTTGCGCTTACCCCAAGCAACAGGGGATTTGCTGCTTTCCATTG
+
'!(&('&$(*"$&%'%!')%"*%&'!!*#"%(#%"%$&$$))+"!("+)$'!"(#(!%%'*'#"""##(*(+""&($!)!**+!$#!&&!)&)''+("(""'")#(&!!!+'+)')(+#)!
@r7625
CCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCNACTGAGGATGGTAATNAAGCGATGAAACATACTGAACTCNGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCNCCGCTGTTTTT
+
;H6=,!2=;=H+5B'DA5F%AE/</,EG(%+'@!9/'94;=8"7F*%B>:)*4H6<).*/BBB*(43#@5:,6B,+A-?2.,#*@E?:(-)=02/6E7D'C/60)&#+)BADD&8/6&>A)3:1>)B7;4.1>:+3;,.FC>@HB8<#371.%0;>6GAC>GDA;3(!9&,@/($<)H?-*G0&<(9B@"G$AE)G0.'*4+)!D!:+;%F,#
@r7626
GTTTGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCG
+
%H!6F/-5,C:<&1/AF#H98!@@A589":D";9+A(&3>=22(.29.(G
@r7627
CTGGAGTGGAAAGCGAGATGGGGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCT
+
=,!&85'ADD?!GF4+F13-<,FE.?B#*&5H96D>/=HD7"#%36$1H&3##'8>-
@r7628
ATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCAACCTT
+
%C?)%,?C4$?*F8@5?,1@:,$A,/>'A8E?0<B"6"%@HE?86!GC264D0D066@
@r7629
ANGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGNCTCCATCGGCGTCATGATGGCTCACAGTAATT
+
*#CH7%*94?+@*03-D;*C!!E!899(G!A0;-=$%4!1$E8<%)C;2,-1B=!1=>A.0-6B(<?B5588%*<@!#87H<77?:B%!6':+FE.;;>,4:1"B&C)EG7
@r7630
CNNTANAGTGGCCTTAAGNTTTGGCNNNTTNCAATGTATAAATAACAGAATAAACAGTGCACTGTGTATT
+
$!""%"%%&($#**)%$##%)(%!(&"#'**+"(&$+&*#(++!$!&(")*(("+)(%(%##'$(&%)'(
@r7631
ATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACTACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACNTGTAACAGA
+
%@$E"@"3:,G:@'$2'8-A)*0$/'5"?F!:$<G49!',!*7@5.D,!B#7-H).=3$:5D51A*BC?'@=E5:82$0(34(/;<0"(0:(F4:?(#+E-(
@r7632
AANCCTNTNNTTATNNTCACNTNCAATGTTTTTGACGGTGTTTTCCGCGTTACCCGCAGCGTTAACGGTGATGGTGTGTCCGTGTGAACCAATACTGAAAGAATGGGCATGAGCACCGTTAACAACCGGATGCTGGTGCGCACCAATACCAACTGT
+
*)$!#($$!"!!'%#$)!%)"&!+&$#*"$('+)+"%!!$*)"+)%*("*!##!#))!&$!&*)'+$""+)%(!%$%"$%#*$%$!'(+$*&&+#)#*&!&&&(%&"'"!(#!&*#+#*#'&)$'$&#$'*)+*%)%'"$&!#)'**'))$)(%%$
@r7633
CGTTTTCACGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCNGCCGCAANCGCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCG
+
%+!*&%"!+'*("+&($($*!)$*'%$"'!!(%)$)#"%(&'#'")&%$+'))+!"*(*)*!$%(!+()!+)+)!'!$!*%%"#("))'&##&%"(($*"$"%"!%)"!'%+")'*'%**&$*&!+"+$&'"*+''!$*!#"'+!+$&()%&$!'''#()'"+
@r7634
ATCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAA
+
--4$$G9-+>2&"A/AC=H&/:#-C:!>'##C)><"5'D(!
@r7635
TTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGAACTTAGCTTNGATTTCTGCGATCTTCGCCAGAG
+
D8C!5):@G%8EG*>D"<'.'"E71=DAB4"ACD6(#$(<:F>&#5?9BB2/#CH'#*!139E9#+*57'02*D28G/;F:7:3/%6970"*%=*6(H+!=2"-+9D#8'>F>%,$:01?.*"@3)(,$/G6"',0.2;H0*G4;'
@r7636
GTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGC
+
4&2?3G7DH6?1:F<16C-,?7&0&A("50>&DG56/6GC4/
@r7637
GAGCAAAATTAAAGCAATAAGNAGGGGTCTGCCTGATGCTCCAATTGAAGACATCACCACAAAAGAAATTGCGGCAATGCT
+
/'+6/-EG'5E6G08+,0>(#,H.@7;(9D"C0/H2?3$-365#A7#&&6$*;=C&HDG#/BC):2E(@"G477<6-<;)2
@r7638
GTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAA
+
C7%?3B98-EG2*!$1;:82.B3A(A%-A:<E+AF5!;57"E2'',A1
@r7639
CATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCNGCGGGTATAGGTTTTATTGA
+
&8D(/E4*A'7:',+>?*AF70481@?B+>H(D6A+!/1D8.$'3%D/)&9@98F5=&(C%A"5+"2C->+<F(:.A=3(3>;,F-82=,;-E
@r7640
CAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCNCTCTAAAGCTTCAGTTGAAGATATTAAGAAC
+
0>B15'%)=EA+*C3(!CBB9@>$0>+,?<H5F>179"&DH<D!<29=CE(>:+B8;;@&.:CC/488AD
@r7641
ACAAGAGTCTGGTTCAGAAGATACATCGCTCTAAAGCTTCANTTGAAGATATTAAGAACAGNCTCGCAGATGACGAATCATTGGGATTCCCATCTTTTTTGTTTGTTGAAGGCGACACCATTGNTTTTGCCAGAACTGTTTTCGGGCCGACCACATCCGATCTGACAGATTTTTTAATCGGGAAAGGAATGTCATTAAGCAGTGGAGAGCGCGTTCAGATNGAGCCACTG
+
E038:/1(2?G1!G1%/D5$=6(CB@>F37;?+11-)9=54!37:G!#3E<#55!@$)FF*"3%$7@!A@2C4>/:>72-;/2D.#4E!8+'<)'FGB5,D8292''D*/'2#/C+'#6F???7'>(9,BB.'B63/)(5!A>AF"$%3HG7(-/!%%(%<+2))46*7C"69;+?67100'@6>5G,AA%<66)&&@&H*<7?6@0>,1<"8(9#C0G1F2,E4EE5=<
@r7642
NNAAATAAATTNTGNCNTNNCCCGANAAGCTNAATGGCATCGTTCCNGTGGTGGGCNTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCCTGGACTTNGAGCAGGACAATGAATCCTGTACATGCCGGATTTACCGCAAGGACCGTANTCATCCGATCTGCGTTACCGAATGGATGGATGAATGCNGCCGCNAACCATTCAAAACTCGCGAAGGCAGAGAAATCACNGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATAAAGCCATGATTCAGTGTGCCCGTCTGG
+
&"(%)"%&'))!'"!&"$'"%*$'$#'&*#!++"!+"!((+'(!#"&'%#**$#*&'#"*$#%#!#(*)#)*+(!"*!'"!)$*+#"&$')"(*)##&#("*+"!!"#)$"&%)*+$)*($+$*$#'$"#(*'(#((*(+*%'#!)#*%%("(")$""+&)%*%)%*!*#$'()')*)*%$(!&&!)'%%+)*&)'#!)&#+(("#"#%)!)#"(%&!&($#&$$)&&'((!#%'")(%$$%'"#$)"''&$+%)$%*)*&!'*#!)(#%#)!)$!#%!('&'&($*"$#"!'+&(#!#$'('$"+#%+
@r7643
NCATCCCGTCAGGCGAACCAGATGTTTCTGTGCTCGCTGGAAGANGCCATCGTTCGCCGCGTGGTGAC
+
"()+#)&$$%(+'%$'+$#$*#*)%#&#(*"!%!&(!%"+%+'%)#+*+()(""'#$+(%)$)#!#&+
@r7644
TTGACGCTTCAGGCAGAACTCCGGACGCTGGAGAAGCATGCCGGAGCAAATGAGAAAATCAGCCANCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTC
+
#8?5:"@=1*B=;>3B1>?C8*1>2(%@+A2+41F0D29+6'F*F7=C?.).1CC(H.-.$<$#/HG>=)B.4D2F-(-="4!=9%@:41,D-1(C/%*&$H=>,&-@1E69<GCF5DB$EB2)@E@H?C8G5H'.0'5F
@r7645
CAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCT
+
A;/F4;*;02<H+9D31=EF-!=7EBH8H2&4/2?+E%!9C49.)2>785$
@r7646
TGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACCATCCATTGGAGGCCAT
+
A>5F!/-<B#664A$A(F:C8!9=!1BGE3/C6<)5ADC3-;AF4DF52338(&(&2/A$3EFH/./+1G
@r7647
CTCGGTGGTTCTCGTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCTAGGACG
+
#.>?;/$)6/(D>7A05*1A10-?C5DDC(1:B@DG6*@0=B.C$8H7"?>G%:$7GFHC'G)>?>BF%6;+AH!"A$0,;E-D0<"F)(AFE;D5/)GE)69
@r7648
TCACCGCACCGATAACATCGCATCATGCAGCTTCCCNCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACT
+
+/AE=(;-G?0;50+(:=D!?7>+)8*53?2-+CA-7-B*@&?.@&GA!>78$4B?,0>=<C>$",1!!/?;(!'(E;'(1
@r7649
GGTGAATGGTGACACGCCGNCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATANCAGGTGCTGGCGCGATGGGAC
+
+(!%"%+%!'"(#)!%+#(%!!')&#%&'+((%)+&%''+#$'!%)""++**''%)!!(()+%)!&*)!('!$!")*+%""##'&#&(%%*
@r7650
NCATAAAATACCTTGATACTGTGGCGGATGAAATCGGTTCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAG
+
(%)@??::G!?7':>!497E)?CH$144,!D/@=3!D.,<&<6A1++-64B:6F!&6)39D:-*G<$F?"?@@,*1
@r7651
CAAGNAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTT
+
#%$*)"#+'&%&)!+&*$""&*""##*!!(''%&(#''"(*%+!#%+!(('+&!*&%
@r7652
NNCNNGGNNAGNCTNTCGGATANNNGTGNNGTNACNCATGTNGNNNNANNGTNNGCCGACNNNNANNACGNNNNNCTCNNNACNNNNGNNNNGNGNAGGNNNGNNANCNGTGTNANGNNGNTGNNTNNNNATCAGCTGNNGGCANTANNNACNNNNGNCGGNGAGNNNNNTCANGTNCCNAGACTAGTGACANNTNNNGANCNNGTGNACGNNGTGAGAGNNNNANNNNANNTNACNNTNAAAGCNNNAGNGAANGCNNNAATGCNNGTNNTNANNNNCAGTNNCANNGCATNNNNGAANNGCTNANTCCACNTNGTCCTNNNNCANNNNNGATNGNCANTNNNTNCAGTANANNCGTCGNGGCNCCNNGGNGANNNNGCANGTCTNCGNTACCGGATTNNTCCNNNTNCNNNNNATCNNANNNGNAAGCNGNTNANNNGCNTNAANNATNNGNCCNNNACGGCAN
+
!"$!$"$"""#"$$!"#"#!$$"$$"!##"$$!!!###$$#$"##"!##""!!!"##!##!!!!#$!"#$"$!$"#"!#!$!"##!###$$"$!$!!"#!#"$$$#"#!"$#"$$!#$""!#"!$!"!!"$##"""$$!!!$$$!$#"!#!$$!!$##$"#"##$"!"$!$$#!#$#$###"!$#"##$$!$"#"!#!##!#!!$$#!"!$###""$""!!"#"!!$$"#!!"##"""$"#"""##$$"$###$!!!""!"$!"#!!#$$"####"!#!!"#$!#$""#$!#"!!!!!$$#!#$"#!"""$"#$"$!!!"!#$""$!""$#!#"!$!#$"#!!"###!$!#!!"$$#$"$"$"$##"!"$$##$$!$#$#!$!"$$$"##"$"#$#$#"$!$$$#$"!""#""!$#""!"$##!#!"$$$"##"!#"!"$$!!!"$$"$"!"#$#$!!$$$#!#""
@r7653
GAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCA
+
'=#A+CD$7H9/C&2)#;=9$-C@:,@30"E5CH+E#>/G'B,'(/@,'#54/<'1@5=3C"C#8&31/;/+'51
@r7654
TAAGTTATCTCTGNCGGTGTTGACANAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCAC
+
&'*!)*$+!$!#)"$%**$*)!)"!)*+'&)+"$#'*#)+"()#%!+++#+++)(&!#**!+%$)&+&!
@r7655
GTGATGCGCGGCTCCGTGCCGCCAAAGCCGTCCGGCACTGACTGGT
+
:;DC4>9/,9C;'+%))*>)A5AHG0H"'?EB<'@@&@B#:CD*@(
@r7656
NGACGNACNACAAGTCCGGCACGTTGCGTTTTGAGGATNTGCTCTGGCCGGAGGCTGCCAGCGACGA
+
#)%"*#"*$+'"$##'+#(!#"#$'*&*!+*('*'*###%%%*'+"!)$(%'$%"#"+'&$*#*#')
@r7657
TTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTTACCCTCGAACAACGGNTGGGAGACGGCGACAGAGCTTGTTCAAGATACGCAGGCCATTGCCC
+
D&(0%;/6:1*8/?F-<=,!'&F7D7:E*4HA#@<C'=;<A0!4@0G7='8':3?:7&')==(#17&B6$H251C7'D-H03A%G$%&#*=D)@<A-++8:)#%=5?EG4F
@r7658
CTTTATAGANNGTNAGCNGNGNAACACCCTTATCTGGTTGCCGACGGATGGTGATGCCGAGAACTTTATGAAAACCCACGTTG
+
*$%%!*)%'#"%)#"*##&"''++*##$*&##()!*'%)*"%#*&*#!$)!%**&#*#!*'$$$)#()&)!))!!#"$$&()$
@r7659
CGCAGCCGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGC
+
EH@084($%5B>AE%:,:%6*G)%%5&A,B!#B>"(2A7%B2:$<9(24D0!,:
@r7660
GAGAGCAAAGGTGGATGGAGATGANCCTCTGGTTCATCGAATAAAACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCT
+
H*2<81'4C(6+*A9BH/2-.42:,2%-:;-6!(:<6BH<-'<,104#2B()BA!(*@>625-1"/-*4DC%79#7#:C03D$#?3136G""59#73B-?(#'3C'6)5+73==$"
@r7661
TGTCGAGCTNAATATTCTATATTGTTGTTCTTTCTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCTAACATTTATCTGCATAATACCTTCNGAGCATTTATTANGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTA
+
5GF$@B1)"75H?.6D?<3H9A-6E;.*B2C'/"?18+A84%:)'4*#H;B0#@9++&$*%/H0@0$9G34*87.-*,3;.*E05%&+H115'%!H6<GA<%62;G6G!4G8'/:9"7%6@8'5!)G#$"E%C03B;5D5C:?)$.0'#BA()0$=@
@r7662
TCTTTGTCGTAATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAAC
+
+'(!"&#+%"+)*'#)!*!#(+)$"!)"%+!%"%$'"!"&*%!'%&#)"!)')"!(*%&
@r7663
NATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAA
+
!BC#/-.)08G50D=2*$)%3::A&-&FE@:,D!/$*&:D*(>C7(>81A;=#0@5*%FG%$%?6/=>)99EF-2+#3:/
@r7664
GGCTGATGGTGCGATAGTCTTCACCATGTCAAACATCCACTCTGCGTCGGTCAGGT
+
.49"*'#B"-"+=-;<#F%1.:6"FEB0!3.4<+-F<3FFD5HG7(;A=">6<6/F
@r7665
GAAAAAGGCCTTCCCCAGCACCTGTNTGAATCGCTATGCATCGATNATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGAGTTTGATGACGATGGTTTCAGGAGCGCATGGCAGAACANATCCGGTACATGGTTGAAACCATTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAGCGAATGAGTACTGCA
+
+$!'"$G(ED$ADD1$2!9:(7)-$/E#49:3=(9?1G%90/F%;5742#;C0:2#6,C'>?)<"<3.E$H*D!"16??!,#$3'E(*E/%H*$9568AHB;AG66:.,)7"8'.F-06HG$/6)$4GB-F"0$:;G)-#-7/</,44%)C")'*@H4,:>!D%/)"H>!.2FFG43;!H8A9+/)7F3?B)$7$!ED5>5<-><
@r7666
CTCCTGTTTAGTTACGAGCGAGATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTATCAGGCAGCTTTGTTGTTCAGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCG
+
+!*+&&()'*&"#$(+)!&""%"#!('(+"!+!*)#%%'*$#++''"%%"*!!!)*!(!*(**'')#++#"!$*&#')"!+#!#!&#&""*%&("(+++%&!'#$&""#%""#(""'**""*$%"%&"")&$')!#'+&'!&*#$'!&#*!*$"%)!&%!#"'!)(!&%+"!&
@r7667
TCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATCGGGAAAAAGTTTTGTTCAACACACCAAGCTCAATCAACTC
+
6,"56G(8C&69!=0@B.F"6.>G!+2+%C'C"+3E)AAFB,.;H(/A00505',AA1#986,G)B>)>5)6-*8($#%)@A'#H;/!
@r7668
TGATGAAAACTTTTCAAATATGGAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTNAAGTGGACGATGATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATCTGCTTCGACTGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGAGGTTCATCTGCATC
+
.AA:+H&5/!=3>0%15.6)!#<?C3.D)42B6"D#+1.>$H.EG)(':$2!(9G2;A,47(>G*$CA3>=,"B3;E5?049H/9""&;4%1*7+9<2(=)GG;00"C=-$3:+0?1D>?D>2>C0-H-H9H(.G3>>2>=>,&%H5C?1;<!6HFBA:1-!;&<C*G'++B-A!&!('"<B8H:&274,)!1E'+21E02,2BHGGAG))>628'>#7-3A4:)C:47":D,&10C?4;,1)ED'00
@r7669
GAACAGAGTGGCACGGTGAATGATGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGNGGTGAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTG
+
(1<.713HBG"8;@/:'1)9F?G'#?4#*A2D9$0B(*,)3)1:#D-924B-E6"*%0:6F97#&5+FF!#.0&?&2?#:)1.91?99@E67,;"!,>*&*!'E'"..64BGA9?G.GBHA?<7'CF,D42C&+@99!=%=&.90A;3+==:C$D-(EG(!7GC=C4$+,,9(<?G'#)9
@r7670
CACTGCTGAGCTGCACTATCCCCTTTCTCGTTGTGTCCGCATCCTCAAGC
+
@4;*F=3C,<G?9HB()E,E#/;)!C6&>5=FC0!,15?'$@=4#9,;H'
@r7671
GAGCTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTG
+
4>1=/EEA&5"!=3B;)EF++A)A.8C9;=9B5HG"5-:$0!!CG!67:2H"
@r7672
ACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACC
+
29HH5=7G8&E%DH2F%:;2!3(@B0%%+6=0=5H+C*<6-2*9.)#G4&;/-+
@r7673
TCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAAACCCCGT
+
1%0'HC/+%"9.,7&4($"&?=@'>-@65&!<H69?D);F3987#&DE75+C27@0"3)692871E+5E%%G#B3
@r7674
ATCTGTCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACC
+
+%%'+&++&!!+$"($$%!)&##'&$'$$*!"$'!+&+!&(&#'$$*+**%"&#()$)
@r7675
CCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATA
+
38<2+'F8F&1$=E7H*#-009AH-3!;?-7"09H305H?-4/8<&
@r7676
CATTCGTTTTATACCTCTGAATCAATATCAACCTGGTGGTGAGCAATGG
+
C>,5=#'<49-0-5;#91?,A'!0@;G;G92C!/.=4198*-!"H1/:)
@r7677
AAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGTGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGTACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGGTATATGAAAGAGAC
+
%=-,"*19<9:E%+,-5-0*&B3A/H/&H5=&=$8#F<?C:'89G:8$';B#7&<)A.0-D/7!=5@;"FE/C!E=$AEG/5/?/G<B*GD-G=43E+01#=2!F9!$4C1/':"5%3=?-30;&!=)D5+6H@0@.@@45A/,E:<;)!$(88&.F="=D"+><.A9:47676=0:>+?/$>FG!G*;,H<*0;E8*$7=9)21<1
@r7678
TGATTTCCGTATGCTTCAACGAGCATGTCTNGAATGGTTTTTACTGAGAACGTCATGCGGCCTCANTTCTGCTATTTCGCAGGTCTTTGAGTTTC
+
9CBF<&A=H>BF1/82?CD*8$,HF2@'8D$7!"F+5%'%,,%"!(3!?=>,")3?+!$#@9$;/<!>H!>=H@"$2#HA>6>"F1E-5#).<-@
@r7679
TGNCATGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTC
+
D5@C3#4F69%/;%5F)E9'E8B9;E+&;,C.#)@55HB2";+A3"8=&<59AGC5?'$",$3;@A%6,H,D24H.D*#C#
@r7680
TGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAACGAATC
+
>6<=)</>*F.7,,,*4/5/;?.7!>!3,-(>'B/);!8C'%05'EA$E!7D=0*8.;
@r7681
ACGGCGTCTCTTTGTCNCCAAATTTAAGATACTGCTCCTCCCCGCAATGCGGGCAG
+
0A6DD*9="!;CH$;>!0<7;%@0@,6((6??8CG+?@H?'*DH@<8+&C!*"E,"
@r7682
ATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGA
+
27,//9:F8?"8(%8**C15G8%!,.40B%!E7462F1<H0H(G1B8F?E8<(B###D$,92A
@r7683
ATGTGATAACCGTCCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTNAGGAATTATTTTATTGTCTATTGTATCATGCTAAATGACAATTTGCTTATGGAGTAATCTTTTAATTTTAAATAAGTTATTCTCCTAGCTTCATCAAATAAAGAGTCGAATGATGTTGGCGAAATCACATCGTCACCCATTGGATTGTTTATTTGTATGCCAAGAGANTTACAGCAGTTATACATTCTGCCATAGATTATAG
+
7%=>C7$B$,B@8:C))%-+F(+BE?78/E3";65HH+,HCBE&;-3.D819/$?(6!=:0FD";/+78&/92H4%-A)%%4%$/;5$A0@)C*76G;:5?!-CC$*'@-@@'?C0;=(D+="GGH.4.7":?##;).,H-H?6!>6*>)%1!6("+CH(3@43(,1*$+(G9+F)*,DG5$F+$&&BG@%,$*%@B-F-)/=+-F>BCF!$=/3&#!'B#80)&#*8'+8<<6,4C88B0%18+H9;7$0E;"!F.B&+-5/251%"43,>B1'<0.4(,;#D(G1%"-%6A'A2=:#<8E67B>81=%@#GEB16E,84!6<
@r7684
GATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAAGTCTGACTAACTTTTTT
+
<(H(8H?!F8.$B!@@"9:G*4'>%=B2G&)&C=E:;<#168*/5.8%$A:!7!
@r7685
CGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGAGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGNTGGCCTGCCGCAGTTCTTCAACCTCCCGGCGCA
+
"8:7;))7'.D*.&59D2,>";F?HF79"82B'1(9?8*"86B-DC,D-:$D@"+F8;%!/7'*G53>0351'G!BB&-$%1GDA'F>7.D:<G8;FDEG+(-E+-7?6$HE:751>3.=37&%$>'*@6$'A<%+3>D/D/!>.3/=674=/CH:,?G+('6.80#6;*6@=/A.71:>(@/5"848'=9A4C=%)*5'/?4'
@r7686
GCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGGGCGAGTGGCAGCGAC
+
)+'(/'*0*:/;E0.130)*$H.-&(@%!#BC"3<4+G!@6F4B=-A)?:"?"1>;=:E=1==/B#7&H,(9@$@=59G-+=0E05?F3D1A69&C&*H!62(
@r7687
ACNGATAAGTTCCAGATCCTCCTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGATATAGCCTGGTGGT
+
$'"+*&%#%($!!"&%""%)'*+)%)&&%$'!%&)&!*#'&"&)&$()&(%&%+!*&&#'&(#('!(#+"*%"#'*#+)")++$*)'$("()#"#"'$'$"#)&)'$%'%"$(($'*!!%!+++$
@r7688
AACCAACGCATCATCAAGTGCCGGTCGTGCAGCTTCGTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAAC
+
+'@%88509AC<9A<.#!&A98$H$=.2,24#*8:#92@(G9#("F49D,,D..H)<@D;17%6$#;*9#.6F4'734
@r7689
GGCGACAGTATCGGCCGTATCCCATTCAGGGGAGCGGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGA
+
DDH0B9B-?C;/:,,8!+D/"!,8?59,$5>$:'GEC*G6BC63>F/$"433.F#(8(9H(73,2FH,."2F:@1G%$4/$
@r7690
TGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGTTTCTGTCGACC
+
3.&8.BFD9*@B/)F6A:"+!C+B2B6+CA8;,890?/2*GBG8.8426G?1(/A=9"(6';%/.,=CDE97F&D?2B0!#$.(';@0
@r7691
CGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCTTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTGATTTCTCTGCCTNCGCGAGTTTTGAATGGTTCGCGGCGGCATTCATCCATCCATTCGGTAACGCAGATCGGATGATTACGGTCCTTGCGGTAAATCCGGCATGTACAGGATTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGG
+
3(!>+%=!5(DC!%1-A$$$+">E?(D<1*H)=7+/'+1G/+--%+FDCH@100-8+3,,+7==@:.0<67*A&80>?GB9)-+031+4&3BC5&575=HG<1AG/;(.C(--&H<5D.G<6FFG,GB7+((@EG.'@#A"HH5'@/70F8#G#4<>-.)B58<BG&E$6)3($>7('8(;+.>C1#&-45@>(96G"0?HGAG'5>@!GG'B?</$>#!5.5,D?1/<2F%#C&6)#>G$+4D63:6E5>8,80!DG*.3!4>F1>B4<)@!7E7H*?B9+#/359<)GEH-(%D+3:85%D50B:/">959$=
@r7692
TGCCGGTATCGATTCCCAGCTGGACCGNTACGAAATGCGCGTATGGGGATGGGGGCCNGGTGAGGAAAGCTGGCTGATTGACCGGCAGATTATTATGGGCCGCCACGACGATGAACAGACGCT
+
++&"$)'&$*''#%*!$+&)$!'*'#%""))!$"#+$((#%%%*)+'%''#$'+!%%#(("$&$('!++&")#+*'%*"%)+"&%!"''*+&)()&"'"!$####)'"&%$!('$%&#!&'('
@r7693
CGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGG
+
(1-1<%/@$?"$+7ED*H?;1B9&5>G%H68D+#A4G'#1'@<HH(&&'A#;&?>FG?$*+A/>;3)@:@C*D,73*7382&)33!$2E2#478H6A:0<7#!!=8+<+CB<GDF>9"9.0E&,?A&81<F
@r7694
TNNTNNNTNNNTATGTNCATCCTTGNTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGC
+
&!#"")"*!&#(&($%!#+""$%+$('&*!&+*$#(#(*#$')+#*""*++()'#)'+$$("#+)&+(%!$!!(+
@r7695
GTTTCCTTTGGTGCTACTGCTGCCGGTTTGTTTTGAACAGTAAACGTCTGTTGAGCACATCCT
+
<@92?.*%90.26H+!';$!1>3'A0*8?+,%>529C$B#?G8,:97;BA?*66C1H!30==C
@r7696
GCTGNCGTCNNCCACACTCAGCAACTGCGTGGACTTCAGGTTGTCCTTCGCTTCGCGCGGGGTATGCCCCTTACTGCTTCCTTTACCTATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCNCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCAC
+
'")%"&!))"%+&*&'()*'!%"*%$")$+%''"$"+&%**')%#$"#&"))!+%+%'++((!+)((+*&'")'$"%#&"*)%!&!'"$"'!+''!'"#%#)("(((#*(+!!!"&#%!!'"+%('%$#)"('!+#"%$*(#)!"+))''))"&%%$%%&(!$$#'+*#+*!'%#$!$"!"&!#)%")(*"')(!"'))'&#"$)#"$!(#%&!'##%#
@r7697
TGTTCCATACTGGCTCCAGCCAGNACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAAACTGTGAGCATGAGCCCCCGTGTTATTCGTCGNTTTGGTGCCGTAATCGAAACTGCC
+
)D<,99A$;"--3'&>H4/<,#>("'#28<DG,)>3B)7=!,,:4(*8-F3-'C1>><<*++/E8D=G%"6'D5@;D8$@C3#E3DE7$02?9"*H:10;1,A43;C:F68D/6'G+<D.;8$<$;4++22B1"#2(56?#&$8
@r7698
TGGTAAAACTGCAACTCAATTAATGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCT
+
>A:!'97C:B->#G)/D745&,+#8'#7#G(+2#58D;":*4=/D?3F9&4H:.:0=,2#60;C<"0@(<5F9CD'0A%0F9>C4E?2/;5=48@15B$6*4(1/0B>6#%>F==95H71F&%28-$<C)E0
@r7699
TGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTGATAAAAATCAATAGTGTGGA
+
17&*@*A>+/8=<,-&G-3-.$A0?&:?997?-G,!)#8C"G=2<-00BG#/.0D<5%2)A>#
@r7700
CANGCCNTTGCCCGTTACGGTCGTAATGTTACGAAGANGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGCTGGAAACGCAGAC
+
'(%'$&!$+$()+)*##+*&"!#'""$(#%+*$'+)$!)#(!!&"'#!+&#)#'$#%+&'&#)#""**(*)"("+$!!#*+""+"&'""+++!)$(((#!*)&*&+(%%(*!"+)!*!+&*%
@r7701
CTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCT
+
=D7(@0&%3<@/#--55D3C3>G(?,?#6C9+C*F6&56%AF-8DD3FD9G,)1:.A(=*A2;A+1("-$*89()($G9D)77E;@%H4A=#G+9(A:?@2?3/.+H/?.78H#4
@r7702
CAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCAGCGCACATGGTACAGCANGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTA
+
>BC80B?<A3-HH?;(HE6?C!#"8=3:0=!D;3%G5;0);2'1(2@B#*2HH8>220!B,9D313//->,)-A$688-?G*@+6A?HD#AB'40G@88"903!2'B,-4(8G3CD*-C6=F$=<2;#
@r7703
AATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAATTCAGTCAACTCCCTGAANTGTNTTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATTTCAGCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTNTCAGAAATTCA
+
*5?.B<@F7+00-%A'5@:%$C++(:)"+155B1;3;A;FC$G6,?E%$-*%31@CF',F#F<(/*)G+B*A#$+8G*--:3F9H<CG=)/!G<3)'-AA3.12-0A3/6<%F/C',@HCA>@5F2%7%BG!B?#%*C3D4;7*H8>#7-HB6"=?3*&(E&%)G$1(5;HF>?)9.3/D#G;(!AG)'#1D>C:21?=81++@D.B840<<8&'<%A&!E-AB0=,9>GA*<57*5/HD<".?$>,DB(E?#C-(F#;F"$"<
@r7704
AAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATT
+
1-:'D/;/25H3,:"EGHGB(&AA:7%%7?%-9:'0((31B,5:;=*@2'+@E-G8
@r7705
AATTATCGTGCTTCACCAACGCTGCCTCAATTGCTCTGAATGCTTCCAGAG
+
%+&!)+*!(%#'$)!)(+&*&+)+('#*"%#)(!'("")#"!$(#(**&(!
@r7706
NTTGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGGGCTGTTGGTGGCGGCGCATCC
+
!*#D5.)H=4-2>H(&(!749G2852DH2:A>,$6"!)5$C/AF-15A*$&8B4(C0.BD
@r7707
NATGGATCATTTTTCCATTTTTCAATAACATTANTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTNTTGAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGAATNGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGAT
+
#+!+')&$$'+&*'&)('#&%%*+&*')'+&(!)++"""$$#&%'"$'&"$*#&'*"%!($&*)!*)&'(')&$"%(*&+$%!*)*)'#+'&!+"**$*!"*)'!)'#$+($&$"'+&"$+(&+("%+*'*'$&$+))+&+%!$$''**"%*#*#'&#)$$&!!)!%#*(+!)%#(&(#&*'')%#
@r7708
CATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGC
+
E3A&4)8D;;?!)=6<0<+!)D./48-"#"<.4'4;B,4.:>B=,H7,*=
@r7709
TTCTTTTGTGCAAGTCTGACTAACTTTTTTATACCAATGTTTAACATACTTTCATTTGTAANAAACTCAATGTCATTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATATATTTCTAAATCGCCTT
+
=!'5,?=:$3A=7"<H1-%'HDCA6E!118&:D@)!;><9<=:->0F-1*;AHF%09.A&3/1;HA$44#)5+9FBA"D*F;B&**F)%27?%D/(G!!<A3E?B5@/=1#(1+95B'<H,DD">G(1,.?2??H'*F.
@r7710
GAAATTAAGCGATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGAT
+
$B>.-B.C+AB('F'/>:H=-9*@-G8),==A7%#%+55'?50A%?@11
@r7711
TGAGAGAATCGGTATTCCTCATGTGTGGCATGTTTTCGTCTTTGCTCTTGCATTTTCGCTAGCAATTAATGTGCATCGAT
+
F:$(C#&8!,B(5.61B?:9&14A&&@"HE-.*7CG>)@%%9,%>0(=)/-=5F",%,#84<?;78?7#FH6!9DG!G(<
@r7712
GCTTTTCCGCGCCAGCGTGAAAGCAGTGTGGACTGGCCGTCNGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGG
+
?/=$&.G+1H:%H;0H)"&$/D.!1A,./@+DC1:8)3:(*%!=*!@/3&(7<?10C(3D2#4-,'*9=-;$)&)//+8+F!/,)2;67$B$B9,/+
@r7713
GCTTCATCCGGATTCTCTGAGCCCACCGTGTTCACCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACC
+
(?D*#D0F?6<))A1B+($1:2&=$=!-#'(;:E)!)G)#.4+6*4*E4:;#/CA//7'&,'5.,$0"/$A3=.EBA1$ACH,!;;%>#D
@r7714
AAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTATTGTTCGCCATCCTGGGAAGACT
+
5D!57=6$>#(61,C)"#8D#*#F7A"'B6+&>!*F)&+)(+?H2?9,$.+:"$D?@(!;',)G00;'(,(=9/,D6&(?6
@r7715
AAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATTTGATACGAGGGCGCGTANTTTGCATTATCGTTTNTATCGTTTCAATCTGGTCTGACCTCCTTGTGTTTTGTTGATGATTTAT
+
B!;505G#3+G2=%"1D3H06@F93G@F2167":F@!!A?3>90!E#07)C*%&:B"G?;=F(!D0HH!#0A3=2.!+CF%'8<6!4E9;:<53@*))+3$1#1B!':B<,('*."4E<81E!@B*H+;.?C$@G&%.#F-H29)D>."-@,
@r7716
NAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCAAGAACTTCACAACTTCCCTGACAAAC
+
"+&+#)!+$#%&$*+$%&)($(+&%*!%$)"+%$+('&$#+)'(*)*+#+#'+)'+!#&+*&+!%*#"!*+!()&!!$+(*$#%*!!%($%%))%((((!&$*!"($#&##*%*%)$(&(%&"%&*&&'$"+!("&(#!'(+*+)%
@r7717
TAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTNACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTT
+
'=0D#B;E:3.&+H.B4#)27*GA"$-,E!*D5F6<-B!%2B'1E12?%)*?>#&$B9<7>::@/)$2BB#"8A@D7FC+'=$?#B57+8,=H5)*&A.8'#2@#@>2((7861?
@r7718
TATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATGTGCCATCTCGATACTCGTTCTTAACTCAACAGAAGATGCTTTGTGCATACAGCCCCT
+
G!9A>=!7.H)C<5=42$&F24'9F'138CD,/2B;"&'5<D&&:A'.11C=8;7B5=&CH#5AH.D4C"13/<$$C7!3%%90$=77$,96/'")
@r7719
CAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGNAANCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCGTAAACACCCAGCAGCAT
+
7B)7=F:&)'A(6#/5?#%6CE73*EA0@&:.#?#AB-C$0"H'7$C'B8"3>14:$5/D.0%?*EG/C$4%H880!09C6#1=4$?F"A@<<C6,*76H2<CF5>=)=$:$G?H%15#0$;AF%-B-*<B008-%68CAE.8"
@r7720
ATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATG
+
=<2AE=7$7);&95&-E*4*(F$C!!),8A7'G7>.5/=*)@6!5&C!G*F,$DC'!@/-5=@@G-)4&EB8&>
@r7721
TTTTTCCTTAGGTGAAAGCATTGACTACTATGTTAATCTCAGNAAATTAAGCGATAGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGNAAGCGTC
+
(*(#+%#'"%%*&(!*(%(*%(*+$&"'%'+#("&**&!$!+&$'#))#)&#$'''#)!&()#)#!'+&%!"$#&)&%&'%)&%)'+$+)#"&!+%!!"#++*"#'*$)$'+'&'%!%"#!"&('%)(')+!#&!'(#'
@r7722
TCANTANTCCNTTNTTACAATNTNGTNNCTNACTGTCTTTGGTGAGCATGGTGAAAAATGCGATATC
+
&#&''&!('('%"!('*&%$(!%#'&&"#*!+"#!(!"&+#!*##+#")$$%#$"#*$'###&!$"*
@r7723
GGTGACCACCGGCCATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTANAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATG
+
5<A8>7G7$:C%B('G=+.A@:+0:/B1"D04?#C''<0A+GC"31+6!E:728&53.0:A;9;:6=BGEA$0D3#080/?8";:G9D?""B(C507D;-'2.*):E*<=+*F(EE,#!11G$>-302>7@&C3=D$-B7G"D+@;)
@r7724
TGTGGANGTAAGCGTGAACACGGTNAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAA
+
1:E=7!461>C$@;F%-:(&9*#>H?:@0H7"49@AG$7@+1'#.F8'':&.B@0CCA(=E4
@r7725
GCGTGGTGTGCAACCAGCANAAAAGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAG
+
58B9)@*(!0F2C7&0+-H)!##$5:4!:DGH(5%05;9=>!3-(6FF$(D?F*528B:9::5A+-'>"7@@!-+:5>13+4;H@$'H6<5-FC"6(/!'-/!:,02)>@>?>EA+=$;8+?=%)GFHC!/1-.3?$E8:G5/:$/
@r7726
CAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATCCAGNGAGGATAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGA
+
0&;9C%,8.$(D")H'43(48<B,/!D13:E-$$#"=+%A5%!!*F#>.=FBH%7.BF#35E(@$,"FDCH./A:))9<'!E!A7E9?!)!=/D5-A!5"8FG-;!@B73?E"B6'-CG/F3$*62#1%.A?7H+@81(3H!,.6E/9,;7'
@r7727
NTTNTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATTATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATGTCG
+
!)#%+"'!)'"!$#(("*%+!'(%*"!*#!%'()(&"'"#$+'"*&&#+('*'(*(#"%)*'"!$%%$$'+(&(&*#+#&%)#"#)$+#!"($&"$**#++'+#"#&(!+&('&%!)"
@r7728
GCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCAC
+
('@:01*,-$(!FH?)47,5C,$)+=&<+@.).),=%+H:3#D"2#<9/#0-DEA>9:6G&+8
@r7729
AGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATG
+
-#4,&3-6A*)..>2()&E?@+$-=+@8?.'';A4():*94A<G"17/649<'084'$G6#5C9!$>B=GD2HC1(+
@r7730
CGGGGGCAGGCACACCGCGCCGGGCTGTGGCTGATTAAAACAGAACTGTTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGAAGGGCTTCGCCATGTACNGGGCGATGTTATTGAAATCTGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCNGGACGCTGACGCTCGACCGTGAAATC
+
,.F;4G*4FE+B:BC*80-/<*&G,2!'A!-C9+@8:)%;?*91@(=#'@-5;),'('9,/)<:HEH@0HE<0::$A"A:;>>@-?GH5/6+12*93>=B-FE;DB@*H="*?3E%$(E-(>9>H,)?3,.9-G7?(E>$*2;-8A=$@A5,79,D=(A;5=!368D*6)7B75$6A9>C2GEH%6H>5%8<C"&GB4"=/=E138*3+'98H
@r7731
ACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCATGTCCGCCA
+
1%(FEF@>:</EF9*-9@5'=(A0,9G@"+*?3-:(:"0#A>G@!D4!,/!)74H.CDFD8:8#
@r7732
ATGAAGACCTTCCGCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCG
+
(:<?9&=%2A&3:8A!:@'F,A#:'G"F+(=21'!B)6%HD%/A%G,E;'+@9)%&H45%2A<"@'D0F'8B(77F>8A?:)!?CF:F3"+'$E6111$(<-A:B/=>E)C;62C4@+A5!<#E/-08?%/8
@r7733
TGATCCTGACCCTGTTCACGCTTACGTCCACATGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGA
+
FC;#)<#".#%G8:>7(*,"+1@?;80+*.(@8=*.'$'16FE0+,)"-=$B:$!/#:@&9?3=.@(-4@1.;402C:F'?G%?:<@,&,H5<"4G.+1&2H>0$G?54,+B-CE25#D(H"8:@
@r7734
TTAACACACGTGCGAACTGTCCATGAATTTCTGNAAGAGATACCCCTCTAAGTAATGAGGTGTTAAGGANGCTTTCATTTTCAATGTCGGCTAATCGATTTGGCCAT
+
+H89)?%E:8D81A7*:==@8)8"CE+<E>=D&.6-32!$#$A&?:,80#)>.<(9E+9'@+&2-%97(D!!9=7;9=+*$;"6/;@4-@5A,0:7+%1)<-:#?;/
@r7735
NTTCTTTTTGACGCTGTTTTCCACGTACNGTCCGGAATACACGACGATGGCCACATCGCCATACATCCCCTTAT
+
"-)FC56.@9=A258)/F&B3)>"GG2*;F%>+3/&$<6*":-0E6=+!-3*9A<30F8H%-DD.628;E>1:C
@r7736
AGGTCTTTTTTGTTGTCGAATCCAATCGTATCCACTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAAT
+
39/6G>":*.$'&65:."*6B3A?BH">9H=0G960$;B/>0<)?C54.#65/GD"0E),%;7&+%+#8'*);4<31+''*#73A9(6<C+?7=(G!>;;!=FD2E(&'E
@r7737
GCGGCGCTTTGAGCACGGTGTGACGGACTGTTACACACTGTTCCGGGATGCTTATCATCTGGCGGGGATTGAGAT
+
.G;C!A3H2,++5%5?A.2?:&836@B(+'0%2,28#6(.$=G=,?5C.8&D-<!7,9*/@C++G(H#)/"<!?+
@r7738
CGCATCATCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAATC
+
-DC/';85**%-#H+DG#$2F&F69H;.;'8$1%#C9G*G35C%E)%?D)+>;E-3-<6
@r7739
TGACATCACTGCNATCTTCTTACCGGTTATGCAGGTCGTAGTGGGNGGCACACAAAGCGTTGCAC
+
55F1@*,20@D(%%5%(@&*H$#*.="4":>90@G"40B(5H2D<!(/BB4,.'96!##-05-+*
@r7740
CATGAAAAGCAAAATCATCAGGGAGCTACAGGCTCCTTTTTTATTATTCGCATTCAC
+
1>+?G?HE(#';'F0*@1B,&@D8D$#3B;(*F,=)1'E#D/"+#+%.;)4(-6F2!
@r7741
NTTGCGAGGCTTNGTGCTTCTCTGGANTGCGACAGGTTTGATGAC
+
!?9'5&2DF1*2=77BH(B1(.$+:$:&"9D;40B1"<*D<443D
@r7742
NATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTA
+
&E20-<:-!-?03!.'/$'3761G/E?%,(0?"12-.A@++@@)?2E+
@r7743
CGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTNATG
+
+&#+%'%!!*%"##%'*#$!&#*)&!)(#)(&"+'!"*%!"!)#&(+(%"'+"+&
@r7744
AAGAATATCCCTGCCAACCTGAGTCAGTTCAGTCAGGCTGGCNGCATCATTTTCCGCAAAATACGGTAA
+
!+87%%@#?<12&1-?/#BA&'&B?1.G:9"9="/8&*%D8+=$*A<G<1<AG(>$/&&4'2)(!G5:;
@r7745
AGCAGNTCGCCCGTGAAGAGAAAGAGGNAGAACTGGCAGACGACATGGAAAAAGGCCTGCCC
+
.?+7+=!<$$GDE0G627(&DA.@)/)$$885D'&@DH-""8'*D/64!?,9/-H!88+G**
@r7746
GGCAGCGGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCGTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGC
+
7)4$)78H:($=B%!,,B,/.:$2C%&-F0'AA@34>/;H156@02D3GF97)(#@2@';H)DD=7$'+<C"&*;4<E$+2><42"H**1C;*0B7&3=-038?/*5@%%2@%%"HB(.&&&B''!,472>/95:0).0*%)-=?.?F7F#=4C:;(?1>%1%@G<)**E;+E.94E57'5CC-*:,02$8-A/537HF!9C2#
@r7747
GCCTGCCGTTAACCGTCGCCGCTGAAAGGGGGATGTATGGCCATAAAAGGTCTTGAGCAGGCCGTTGAAAACCTCAGCCGTATCAGCAAAACGGCGGTGCCTGGTGCC
+
1'$&?4=,(G$=83,A&(G=6,1C*0E2+**&*9=>B(FE,@G#:G195E<C(1?F=",%G?3&03%!("&D1C8%<7"E.%;F46@)H)G-5%9&CA)$<B("3:2D
@r7748
ATGCGTGGCACAAATTACGTCTCGGCGTCATCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCNGAAAGAAGTGGCCTGACATGAAAATGTCCTACTTCCACACCCTGCTTGCTGAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGC
+
EH77-366%844."'D&D++/:C-B"8+5!8&7?<8?&*0&8+-/;E=>/CH.-.#4%G;&<%/<5/'5D&!DC7</F;7-(-BG3BA2&;"HG9(2G)F7AG'4F3E0/3!,/!:@DG5F:C0%G;61E%(125=;308*<B+A)%+($,A9'("-.)0
@r7749
GCCAATGACCNGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATA
+
4=3*+8!.+1@DF;D<$D!9972;$:>/E)>+7"?:,&=4=DH+2=>':5FA-5!=F)&E-8+47D9"()
@r7750
CCGGAGAGCAGGGGCAGCAGGNGCTGCTGGCGTGGTTTAATGAANGTGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCACGGTCGATGTGTTCCGTGGCTGGGTCAGCAGTATCGGTAAGGCGGTGACGGCGAAGGAAGTGATCACCCGCACGGTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATC
+
!;C-6B+48A,A=+(;*/H#2?C#01%0$D5F8E=,@<C&=D!:>;(#<A+2@H&2,FGCG'H;<3#7-E$.*7/G(=,?!C73"4*6.A62E>(0C'9F47#?FFAH8C"5**#&E>/6*!D?@#0#+&0#>:G@0=$%-!?.E6>454G+6GF.#H#,*</:1$3"5$G722$<9#(>3>4F.';E%F?E1"<+42B:-
@r7751
CACTGGCCTGGGGAGAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCCCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGG
+
>>+AGB"0=E"8+1D)/$+2B0B4-&6A%!<C#&1+4>&??$;;=;24#7H3<7<D$$03;!A4B)"8H-@%A<<";;'5-1D4%",+C2F)H</(B(,!,'+/@$-%9(+4H)F2*+:1?C*6#>1#,2
@r7752
NTGNTATGCNNCTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAAGCTGTCT
+
#'"!%##&'!%+!##&'%$(+!$%&$!%%*&"$*#%)'%!$"&!#(!*%%(*&(#%*%%&)
@r7753
TGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGG
+
=6)@#<@9@4B,'))<@7$@%E82;*+G*@".;$<;!-H:<'<>4G,.1D*;2E&6<!@!@1&E#;9H95)/"-',55*6:0-@?D*7
@r7754
GTAANCCNGTGCNCTGTTCCGTNCCNNCANNGCCGTNAACGANA
+
*'()$"*&$#*"#(*&(%**)*#*(&*&%$(#)'#&(')#('&+
@r7755
CTTCNNNCNNNCGACGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCNGGATGGCTTCAGCCCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTNAATCC
+
'(!$!""$&"%')'++*&"#((+(!'&#''%#%##)"!%"&&''!&&($*%'&!*'**"($*&"'"#''+#*&'!%!%'!$%$$'"#*'$!($'"%$(#*(%+("!")&!#!'&+*(*)%)
@r7756
CCACGCAACCAGCTTACNGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGC
+
+DD@-CFC"E8<4&*<4$-3?9!/,@9=%A&4;<%4F#>'F)!7<)E?%%.
@r7757
GCCAGTGCTTTAGCGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTTCATGTCAGGCCACTTCTTTCCGGAGCGGGGTTTTGGTATCACGTTGTGAACATCT
+
<GC??+(G"E>//062G$::=;%'(,<H$'9&'B<$-6#,8,"D''C:=B!=D/#'12G*!?'@911'"="F?7('$91G3><("&-9=<BADD)2.@3$4!$5":!"B=1B',F-#978D!6)>*C+6F)2
@r7758
NANTACCTGCATAACCAGTAANAAGATAGCAGTGATGTCAAACGACGCAGC
+
"(!%+*#''#&$"#$$)#'"')#$#!$+)%#+)#((((+!"""$)!"()&(
@r7759
GCCCGGACAGGCTCCATCGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGGAGAAACAGGGT
+
-4)*;*E4B.@B%=B*#-/73!<%<(7-'&!&3&419@9H@#;$@8'H+!D,H+?%4H(&A86F"'2'C
@r7760
TTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAA
+
>@A@2+?+6,?#,&@#9@3D-9.A2D;;.-!5E881G6+6E*/(DH;6!=(/0A-16*>;47=&(
@r7761
GAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGNATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGACGATGTGATTTCGCC
+
G8:AB:A?H/2*D330*>583AH)>+A>0!<94$1;-)$*-&8795<?#8D:3=F;&F5.-)1!C;@;%(&E/9:,)#2E>6+*3)2$3%G,1=(E@A-;9)0;
@r7762
CNTGCAGACNAGTCGNTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGGGTGTCCCATCGCGCCAGCACNTGATATTCCCCGCTGTCTGCAG
+
**&'(#%%'")*"#&%+'!!%#)('")!++%("'(#$&*)!$&''%*&#)"""*$+&!%+"$+)"(")&(+''%#+!+(&$*&"%)#+!&!)'*$!#()%"+'$"%((#'#$&+%!)"*)("#"$
@r7763
AAAGCCTCGCTTTCAGCACCTGTCGTTACCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAA
+
AEHFA$@F9!#!1;-3);F&&A>01'<0-6"4'/*:#G6!A!F29*32+28DA81*BG*85+@-%"DC2EEHC+@7$E?3G42*28&'&<<B?508>>@"%B+3
@r7764
ACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATACTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGAT
+
H8>A4H!3CG;<?>5+)#;E)-:E";:6*F;#D)?/)4+!%C%@!4;92@>;!.4H>$"!#!GD>)(>>%(:,;C86=/,E,D6@GA4$"-56;#H8*AC*3/H*/AG%#9'5+$%8D>B'*E6#7;3-6'H=6
@r7765
NANGTCCGCACGAGATACATGGTAAGTCGCGGTCTCTTTCTC
+
"))'+++)!'$*+%*&%'"+%!+++%$&%)#"+('*#&*#&'
@r7766
NAATNCCNGATNANCTATCGCGACGAAACTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTCACGGCAACGG
+
"*%&!))'%*$&($#+%!(+")"%+')!%('&++'!+!)+)"+)"%'(#()()(&(+!"("*)*"&%*!+(!()+"%
@r7767
AAGCATAAGCACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCTGCTTTTGTGAAAGGGATGCGGCTAACGTATGA
+
,9GE$%//)'6E;'8F=1C4D6=EA8'('=8.%GEC0%!24;BD=2%7)):"$(:9$,<%?$*>$%.+=AE8!E8*@G$),92/7"%D9/F;$/H/)?5$G%'&57"9E=FGC)7-C!0$;51,C.=427=E<+(3+8
@r7768
GGTCTGCGTCAACTCCCCAGTCGTCANGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTNAAT
+
E*>6?H>3-6">D2-2@&(':=7>,5("@*GC";*>-#;<B3/D<5H"4#>CA2H$5C@658&?B(,?;-
@r7769
CTTCATCTAGCGGTTAAAATATNACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTTGTATTTC
+
;.))=#1%>8!3(<>$CA4>C8$@D@2!,EB+))&G0AE0/4#"F>47/$=18(2>-!&%C.$D:-7%)G$-*9>6$+A@?GF5$<,A!
@r7770
CATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGNTTAACGGCTTCATTCATGGACG
+
>6-<&%%59#$FCH!%5?88"!:*!A$(>>@15&%C2#*/5ABE36.*#/;A11*?+C8!:.=+><$<8G*:E=8
@r7771
CGCAAACCGAAATCACGAACGTAGAAAGCGCACTAAATCCGATAGACCTTACAGTGCT
+
8+0);8:+C*@*+F:/)".:1A$1:-5<G#E+E/%'08H?H3'%5$516:!9(1&528
@r7772
TCANAACAGAAGATGCTTTGTGCATACAGCCCCTCGTTTATTATTTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGGAAATACCCAGCCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACA
+
!)!'(+*%%&'&%$'#%*)"$'&(+''#'#*%+$"'(%+%'*&($*&)#!'*#!("%'(*(')#&$+(#%*'&*%!)!(!+'$&$##&("*)&&)+)"'""'&*(&&)%&'+)+")"#)+$!%+&!"*'#!)(%+!!!&))(+'$)(#+!&)&))$#'&&()!&&!+"!%+!%'"%%')")%'#$!)%)$&%!$&(+*'*(
@r7773
ATCCTTTGGTTCCCATACNGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAA
+
;/=7..1'</!G/=2!BB,$+'H,9,(&/0)43'<#C(+3F5)G2'%$H=>0,'%9145A3%),&-
@r7774
AGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTAGGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTC
+
0$G&14)2@G$<0#HD4;B-',7F#7A-CE0<;%5%;"GHCD.E-&8!0-)*&@/B.EB%28'!3-)!85>%(A#"6'$E$5=9/
@r7775
GTTTATTACAAATGAAAGTATGTTANACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATNTTTAACTGAATCATCTATTA
+
+&#&$($($"!*'"+$#*+#&'$$'%%+!*(&*+(+%$!)#)"#++"'(#!**"$""('%!+$$!+%#!"$%!*)$%)%!((#'""+$(!$%&+)+"#
@r7776
NTCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGNGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATNCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAGGAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGATTGCAAAATT
+
$2+?#?D4/89%4E".(8H0D1G="$",G,0.$!/G80>=;=)$):E<*($,A/(5(/'9&GD3G+>4.D?!0*/1!E;4@$?+FCA(A3*.F?@E%B9110-7=="@&3:<(1F/(=0C*H,FF$(-)!?H/9A76(.;+!9%B/F3*/A)39)9E?7804*81B3B',/'70;)CH'6,*#'=H,=D;:+*&?3358,5H#(!<7029:-&-C>%4"@?8::;-=9>H(2>395#+?@39+!:7;!</7>%3>D:&8+GD#"-<4$-BBG$GG34C8;-A,/B8"E37(D"0'41$3%:54
@r7777
CAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCTACAACGACGGCAATGTACCCGGTTTCACTTGAAA
+
'1+'#>-GA1BD=(#+=$9A+!&.&*3GGD/B&A54>5!E<'2#0C6":+66(@0>*9#D4CGG@E/%7-'62/6H;8)6;+!$7D*<?/@:9=#G
@r7778
AACGGCTACTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTAATCCACGGCACGGGCCAGTGCGAACGAGTCGTGGGCGT
+
-9@.-:*AH'/+GA77H5#5;,@86:F858'9:6>6F49/D0&6>$D=71/2>'D(/52-.+GCG9<878;'?.41;89*1H1)7D17:"+:=H/#>ED=./#&F(684E34;6/1H9+:!2;.279!:"&#7$%1=2F
@r7779
GTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGGCTNGGTGTCTCGTATGAGCAGCTTTCCAGGAATTACGCCCAGATGAGCT
+
@<$7.4H'573BD.;8"#6G1?F=*0#)7G>G%G)1<&(/#)+'*(2@6/4<>6.9:.63*=%94*)1@<15C;>2=6"##&,*&B;.
@r7780
AAACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATA
+
,FG$E$/0$&0GHH2E$#A71D$BDG@.')--'!%<)H2&H.
@r7781
ATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTT
+
3$D41&11,>6&!;CG+G%D6EBHBH>*D%%5A#130'2FA@A3A="G#.E$E'21?H7$:/F47C3*;;E2F38#!+&"CA86
@r7782
ATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTC
+
;,4<"G=G)@:HB0D'510"95<H<%A#)H0/!>@?29<F&>
@r7783
AAATTGGTTTCGTATTTGGGGAGCAATGGCGATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTNTACTCCGTTACAAAGCGAGGCTGGGTATTTCCCGGCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCA
+
%'=@:E9';,2;6&E3C?&BCB;9/F0>-:@.E%56<>CGG(/&!C7B+!(##7+;!FDC+0G>./--,&7(F/#6E?!=1.)2*F9/,.!=/1&,6"CF*>B"?0<=E:B(@%39H?+.'C1@%>8;;%0A)B>+$-)::&/,4<<*7-;1)+%409H04(':1-&7-=%(?#.>+@<!)E#67.-$;>'
@r7784
CGCCGTCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACACGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGA
+
8D;.1!864#G7B9?&.,45;71&GH$+4>)<(B0F5;CD7<!(C9-!63H30'+%?;1/D(@@#D'@=8"H*?C+;$F#??"#%4/<2*7,,2/<@1(B*C2?+8364G#:8;19=2&H%/%?(,EE2%FB."=+0/!/3<4;@A+7+0@>=
@r7785
NACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTACAACACGCTGATGGCGGCGGCGAAAAA
+
#)/.6?D,@D"4'/=3F?5ED"4"%86:!G%9:;,AA/%160FA>?@.D*8+)-59,<1B##'1)A9(.,7,+
@r7786
CTGATTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCACCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCANCGGNAAGCCCCCTGAACATGGGGATCATCCCGCCGAAGGAGTC
+
;7D5HF>$:G:@G.@4D0/8)7'!@C!$@D;5828)39BB.5#'6B=>7!?<!EC5GBC)!"('2-EG97.*A=.F07#6?$0$!"!5+,:E/F%+EG;4>30H:/3<=!6.!2:)-;6<@,.F#9:43G)#,@?-E$@!(42&"-&H"(?)**D=@!9DD@%3(.B>)<:EE3
@r7787
GCCTTTTCCCTGACACCGGACGGAAAGCTGACCGCTAAAAATGCGGATATCAGTGGCAGTGTGAATGCGAANTCCGGGACTC
+
(F9131#?2=4=<G#G3"4":&@*ED+%*B:9><0=/>H&/C(HB-(:5A)<;('F+*E?;$-/F"(-3B455,H*#@)!,"
@r7788
ANGTGGTGAAATTCCCGNTGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGCATACGGCGTGAACGTCTTCCGAAAGAGCTGG
+
'$(&+"&(%+(%()'"#!*$(%$(+&#%++$#&&&&!!&&$)$#&&%&)!#'&"&%(*)(*'**("$%*+!&"%$#%""$'!(%!"&"+%"**+
@r7789
NGAAAANAACNNGCNNNCATANNNGCGGCCGNTNNNNGNANANNCAGNANNNTGNNNTANNGANNNGGANNNTGTNNTNNAAGNNTCNCNGTGANTNNGTCAAGCAANCACNACAANCNNTAAGNTNNTNNATGTGNNNNAGNNAANGCGNNTTANNGNNTANCGANTGNGGNNNAGNNNNNNANNCNNNNANNCNNANCNGNNANANCNNNACNCCTNCNTTACNANNNCA
+
#$$#"#!#!##"""""!!$!$!!!!#!""$"$#!!!$$##"##!"$#!#"!!#$!$"##!$$$!"!$"#!$$#$"!!$"""#$#$!!"$!!#"#!#$$$!!#"$#$!!$""!#"$$!#"!##$!"$!##$$"##""#"""$#""!!#$#"!#"#"!!"!!!"!$#!!#$#"$#!!!$"!"!"""!##!!"""#"$#!"##$""!""#$#""$$#!"#$!##!!"#$$#!#"#
@r7790
GCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCTAATGGGTGACGATGTGATTTCGCCAACATCATTCGACTCTTGATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAATAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGTCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGNAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAA
+
#7&C*7?%8*#+C'B+4)4?H!,-(<(1A&05=1@+90)68.A.;@(DA?A>8G"$0F7B.+H&7=5.*!%-7%*;'1&,-B5$H-)FB1:H?#?38"0,1',!*C7>A<?90-60G9)B*C$8G.;8744>8:$(A7!B/GA-A?*!2-;="(-D+&G7%%$&5:@/*8HH:;A#36EH@#&/C$1=)!(5769&.+2F3729H('G<';</8DA529F!>#H=59>'!B&@('48?H8,C+F:A7:G@H$8.=C14535/BD(3/85;E.*;/&=.=CG,5.*;E0+$65.5:9:?FH@-:;E(>6/%<62$)B;,/;BC+5C!?(6,#A&&3>)/@?18#)>HH$!$,6-;27":@7H3A-:F:BDA+4@$2!57,EFDD9..-FB*=?.7>?%!5&$HH&=6H25;41BH)"5+-C"8(.4.387$9-F!DF>1#F%
@r7791
NGAATACCGANTCTCTCATTAACATATTCAGGCCAGTTATCTGGGCTTAAAACCAGAAGTCCAACCCAGATAACGATCATATACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCNGAGAATAACGAGTGGATCCATT
+
!#'+'("#"$!'(+)"&*+&%"%$%$*")"(!(+$%$&!"&&'$!+!!(&%**(*&+&#((''%!#+*")#"%*+%*'+"")&$'$%!#*#'+%&'(#"$*"*##+#*$#&##)+#'&)'$##$#(%')&&*)!%'&''#(#!)
@r7792
CGTCATCCTCCGTCATGTCCGCCACATCCGGGGAAGCGGGGA
+
+"!"*%'*&)'((&)$'%&$+)%+$&)+&(%"*""**$%'**
@r7793
ATGCCTAAAGTTATAAAATCGAGCAATCCATTTACGAATGTTTGCTGGGT
+
C#9DG50065:'*G.)B#(G87$=%7-/55?:H*,EA,':5)DBEB%B?:
@r7794
CTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAA
+
:81<#1>A*D7(5220&5!B@C/&8&#F704G'?'?/7"BG/-@8H%(9=*D;3.%-/9,E2=A-&C>B!C?$G%<G(-B@
@r7795
NGCCANCANCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGAT
+
&!#'("($"&$+$$"$*#!*''+#%"(!!"((&(+**("+$%&#&*#)&"%
@r7796
NCNCCATCGTGTTANNTACGCCGAAGGGNGAAAGATNTTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAAATGCAGGG
+
!&$"('%&**##*%$#!+"&')%(%((+''&&(%)&%*#*&(#)**&!%*(*&+"&"#)"#$)*#(++)!&%&#+)(*!%#'(&)+*#&#)))(#$((!(""%("*&+%%"$%)#(*))*
@r7797
TCAAATANGCNGAACTGGCAGACGACATGGAAAAAGGCCTGCCCCAGCACCTGTTTGAATCGCTATGCATCGA
+
#%(#*%&$*(#+%()!+'+!(&)%''*)+!#%$&&&(+#'##'#()'!"%)$!&(!+!!)%)*##(!*$$!#)
@r7798
TTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCAGAACTGGCGC
+
-1E;B#&-6H2;(8!@?4%"#6/>1((H)D8#?&3:<=>B4.2%/FDH5&B,058F71C
@r7799
CTNCTCACGGGGGACAGAAAGCGTCACNCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTCTTTCAGAAGGGACCGAAGCCAATCCATACCGGGTTTCACCCAGCGGAAGGT
+
)&'FD'4&1</<?>-*6)AAF:C"54A<:D=++;,D2.F1E,235;&C,9*(3*+9'(!"7"#F,2*,<,3%A!'.72)D0.2?*6E*C<=@+,'0E*-F1'&*8B*>EG,HB;>!F/8?!9BB><-&A-8F)!7"8,7E@89B1;1&:/:3
@r7800
NTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCGTGCCNTCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATTCAGCGCCAGCGGATTATCGCCATACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCNGTTCTG
+
!:?B-$(7%-*!A'%68:!<>C$0!D;AC+)'A3749C8!!,;FD$1(5C*2!2"&.C079$*"E)88.31#E+0#9E-.F4*3=0B!3-:1EGA!A<2,9@6//<"#$4;%C;7=D%H+2"2F+B%C=/(7-<A9?"897)&!CCD=C;0HD5#*9-'+90'?<E",$9=,%B@=
@r7801
CGCACCGNAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGTTCATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCC
+
3$GF*>%!4E5C,E>8:;="#G">;E'GG*A$+;$EGH,=!=D57>=/;28!G02D&'5DF&9-E%5C?DCCGH(EF%"?2)H;+3E4#CA>?;41)HAF*C6<,!*E-A0!9FF=)%@
@r7802
TGCCGTTTATGATCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGNCGCCAGTATCAATATCAAACCGGGCCATTA
+
5'>F&<6H-#&;.:>1."56AC-:#&=!4:E&:&?(?C@7"()#>H>88.5?+3@;7(DD%.'41HH#2$8?1>H)F+F&D:6@E9';;0"DAG(-0*9#?;H$?$,"7AGF$=!!2,$>D838&5;)4.93,!!28!(H:@#=+C"
@r7803
CAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCANGCAGGAACACTTCGAAATGCAGCTCCGCCTGCCAGGTATCGCTGTCCAGCTCTTCGCCCGTGTATTCAGCGCCGGTGAGATAAACGGCAACTGCCGGAAAATCCGCCTCATCAAAAAC
+
.5C37++;62==9:5>%A/$C5"):2D$>++7F3&B)'1'A6/B,6=+3"E+1G".1G4CC99);),<'B>9D=D;@+.D%7/(9;G/G,$=:60D7=(@0,!*,=D:.+-'(H:54E.0.85&='65351!*:9.(;91,-1D%'D@>/9/71*6/+G+F'95@!0&E+8D*E5#,.CA88E>@:29ED&018;2>H
@r7804
GAGACGTGGGAGGCGAAANATGGCGAACGTCCGTGAAGTGATGGCAGAGCGGAAAGAGCATTATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGA
+
4&211F*=&;+B$?.@95C6*H*,.+*1(4G@>.%$'A))/1@2@>3-66BHF%*>(*0-"+1HGD-&9!"3$5853,DFD$$9-A(-0E.517(AE&31=(5*";!;)3!(D>+59>%(D=>.1>8!!8GC+32+#"CH*?,#
@r7805
CGCCGTTCCGCTACANCCAATTTCAGCGCCCTGAAGGACCGCCATAATGCCGTTGAGGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGNCTTTGGCTGT
+
F$*:6CE2+$@,;)#6'EC)>/B=9=6HD#(#5);E,:7?-GG"0)(->7=1B<;4-1C5A(>.1@9@E2;,1*8),/D+G.C5D3./'"F8:8,@C5C%(4+H@2G>00<D"+-1%>%!?8@>B27E(8))"(-8B:9!9B9/=3@B2;!EFE3/0>*&C.%<18G;F3?D;
@r7806
GGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTCACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGGCANCACAATATCGTGATGACAGAGGCAGGGAGTGGGACAAAATTGAAATCAAATAATGA
+
"<H>!F?'/&2A;0C'7;-EEG><:7+63=,2@0)8;C82C9;8$'(9"50A+92#(*(08%'5$*3!53#.H'3C#D88G6=D$+?=C.*5A8@;9B($7:,$FH'@2749@;GA=,#C0C8,,7%((8494))/3HH%2H(5#A=*3;B$!/0(94H)C!$+CC@:*8';@8%!*$#>/8:G9##
@r7807
ATTNTCTTTTNTNAATTNCACATTATCCTGAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGA
+
!)!#%"!&%'%'%!')(!+&"**++!&&(!)!+%)#!(!*$(!$"#$&(*$$$"#%*(%%+&)+)!$%+%!()#%"&%%"&"'**&*()*$!)"!%'$"&'%')'(&$$+%'!%$"%&!%+("))$%*+
@r7808
GCAAATCCGAAGGCCAGACGGGCACACTGAANCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACT
+
/F(<?(%-A:.63((B!#43&A0%3?,.(9(71:B&@D=4!'C<<!G9G,@&7232!+&&#C@#%=,9-<
@r7809
NANNNTNNNTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTG
+
#)'!#("!+""$!#+!"+$($"%$("!%!'+'+('#'''&$'$!%!(#)
@r7810
TTATTGCTGNCTTGACGTTTCTAATCGGAAGCAGAACGCACCGACTGGCCAANATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTAGTT
+
*&***$"))"+)!'#)+#'*($")&!*(('%+%#$)'%"#&$##!*'&'")&!'#$&($!+(%"'""#"!"'!'*$'%'$"%&('")&'$(!)&(!*!*$$)+$*&#(%%))$+#)")'#+!!($)"
@r7811
CTTATTACAGGATGTGCTCAACATACGTTTACTGTTCCAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATTTCTTCGNTTCTGGAATTGGGCAGAAGAAAACTGTC
+
C,:?G$?*G<*@A?F4)8'1C:D>90,*'"H7A<,/)$)+>0+')7=7,$C;,H%B#2H(,<&A;:/?$6:A.C=G2+5)=H9AD7D!C#6.C-,2.*G5)%90>19"E#@;%&1<"GF$HH;>
@r7812
ACCTTTTGCTGGGTCAGGTTGTTCTTTAGGAGGAGTAAAAGGATCA
+
6,39,$!%#!+!,)4@)H01,D%4B,6!)-,CD@C$AH98C/"G"'
@r7813
CATTCGTGCATCGTCAGAACTGACACNGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGNAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTGTCGAACAGGGGGATGANGCGTGGCACAAATTACGGCTCGGCGTCNTCACCGCTTCAGAAGTTCACAACGTGATAGCAAAACCCCGCTCCGGAAACAAGTGGCCTGACATGAAAATGTCCTACTTCCAAACCCTGCTTGCTAAGGTTTGCACCGGTGTGGCTCCGGAAGTTAACGCTAAAGCACTGGCCTGGGGAAAACAG
+
+'"#(**'**"!(!%"&$"%)"$%*!$+"#$*#'*+('!(+!*&"""&"#((*")+"'!$"#&$'&&)#!'"&!&+*($)*$#%)!*$&+!'%&&)""!&$))&$"$$"%*&$)#*+'$$*')#!*&!*'#$#)(!("*)*&()%'($&*%+%(""(%!!"&!"&)+%!#))$+"(#!&"&)"*#+)!#")+#*&*!+)"**+''%'&"#(*&!$)*#%'*$*(%#!*(#!%#"#*$+%!#"%#*"%*$))'+*""&)%*$)#)&%&+!'"'(''+&%&#*#!*(&*)%'+))*"$#%"("#!*$#((*'"$(%&%(%&'&*$)+("&)"!"#)'*$#(
@r7814
NGATTTGGAGGGCAGTTGCGGTCGTGGAACCCACCGAGTGAAAGTGTGGATGCAGCCCTGTTGCCCAACTTTACCCNTGGCAATGCCCGCGCAGACGATCTGGTACGCNATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCNTCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAG
+
!8$BG&><7=%-/.0D:8(%!H6"+A28.&C@.&=758$1(1H02H"H2)E@:(7C>"H'"@/=E!"&"E=@,!C.7D5%/"??1?E.-(8F+220!A32(>8(E=H75C1HD"1:;#E(1<#7?8=>E!F1D02D0;7';7&>;BF'G;!A28-%%>2-F0+5=..3;+F?0./D4#H.<7G$2=%#,8,',+5*"C14"#4<3,GB77!G"6C!/7<H;&2"%#?B?85G4$5'+)=,G")&4=B,*#9+B9(.%&FED(F.3C@FB!8,#@@5D5=?%!68>+A&0'G*E9&./=)>
@r7815
CGTTTTGTTGAAATAGGACAGGGTTGAGTTGCCCTGATACCAGGCATACGCCAGCGCANCGGTCGCCACCGCCAGCGAGGTGGCCCCCACCATCGGCAGGGTGATCGCACCGGCAAGC
+
0'B=D"+8ACH(G&E)>(B)0#:G'<#("@BFDB#F=?C=G51?940%-+G3723.6:)"H(!.#D8D=:3H#@#3?65:)C5476:23;F*C7-+3,<E3<&&D&6E9?*5%4&2"2
@r7816
NTGCATCAACTTAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAANCTCATGTCAACGAAGAACAGAANCCGCAGAACAACAACCCGCAACATCCGCTTTNCTAACCAAATGATTGAAC
+
":&B",>.3=$1:2?,A%5"?2>E>9?.@A5=)B43+,,-783D0A)6;F7='0..&.E).#@@<%27("!+!(@<<7HD(.#D$D.&,=;).E6C"4<(*<G)8HC==<#=F.?'43G>$C.H$H'@&$:-+@)CFB,
@r7817
GCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTCAGGATGACGTCCGGGAGACACTGCAGTCCCGGATG
+
+4@4./H55@B6'6-F1$F:%A9;4?#%/')G9%-$++,73FB!B6%0.?H#=@7E5H/@-''<,"5("%*;&F>?,
@r7818
TTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAG
+
B!0!H1B"4A@(*@(<>5(E#$GB//.;#*EA5>$EC(D6:HCG1.$/?H);17E
@r7819
CCNGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCNCTGCGGTGATCTGCGCGTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTAATAACTTAATGTTTTTATTTAAAATACCNTCTGAAAAGAAAGGGAACGACAGGTGCTG
+
(#+&$###*"!!(**%(#%'&+)($!$*+)!$%+("%(%+'!*'*!!!$&*$#&%*+"%""((#**'+"(+%(*!()*(($+"'"#%%*#+!'(%!%)"$&++$"'!*((((*()&"++!)"""%&$(!)#$&*+#&*$!+)&*&#"*%+#"+&&%$!))&*&)$&)&+)!&'"#*!#+""+!&%&#%+%!'&!$!*$')(*$!*#)$"$*+"&$#&&!(&#)"$#%*!)(*&%)"%!&'''+'%%#'&&&''++"'$**!+"#
@r7820
GTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACG
+
,0,EA<*2CFF*;,6@=*)#+@D+7H0),'."0")0@@3-$G74H7>4#0.<+?'$,(8E04C;@)B2D+))BH4@;7GA>%4#>*
@r7821
GTCNTGNGCTTCCNNATATTAAACGGGCGCGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTGAAAGGTGATGTNTTTTTC
+
##*"###))%&&*##*+)+%('!%###(!+!'+#)#+!*##!!%$$)()&&"*#&%+$+%)&'%#&&!&"'(!!('("''))%'%(%)$*+'*""&"$+!$++"
@r7822
GGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTA
+
11$F1-G='$0G2;?E:-":C;>(&8.55'4)=8:%;!"8#)?G
@r7823
TGATANTAATAATATTAAAAATTNCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGGAAAGAT
+
8-6/72!H+>"-610*33,2/#5B-;H8;B"0G5$#70;8-@&'&4"):@'9?&C1F">*AFH/+.G65FH3;'F
@r7824
AAAGCAANAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACAT
+
+*$+")&+#''+&*(!")+$(#"#))($$#((%%$#'!"""*(&
@r7825
GTAATTGCCGCGTTCGCCAGCTTCAGTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAA
+
331(*%G6)H9F6'+$?<&:B=)#%G><;(;@,07.?0':68'%6E*"B0==;%<0@"(!1!@D5&;8-@H<=D8(7E.'*A":EA(&
@r7826
ATAATCTTCNCAGCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTANGATAGGTTGAAATCAAGAGAAATCACATATCAGCAATACAG
+
*'*''#&!')'(&+*#!#&(#*"#*(&*&(')%*#"&%&%%+#%$*"'$#!!'+$)(+%(*$()%##"!+"&!(!#(!+#%#"!%+&'#+'&$*)++(*)''(+$##%'(#!&%!#+)%*+%#)'#!+##*+""'"!%(!&$('+&'$$)'
@r7827
CATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATANTGACTCCTATTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGG
+
H+"4</5:7%<&1,#)*GG!*D7:C<?,(?)HB5(%$*)%A01>0&9A<F5'3AC2CC=>16.=1CA&3AC!<DC)14(H%4%&GD@>H6:5DDFC'";B""H9%0B(D3+D?/26+F@>H02H6@?3H<A6(070/*'D+
@r7828
CTATAATCTATGGCAGANTGTATAACTGCTGTAACTCTCTTGGCATA
+
!0)@3G=EH+#G!4@6HA%7)@>&G!/<F-5@DH=<?A;0#0.6/9'
@r7829
AACTAATGACTTTTCGCCAACGACATCTACTAATCTTGTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCANATATTTCTGG
+
'&''++%)&(+)%&&#*#&#$&(%&$&+)$%#$'%$"$&*&#*&$+"*"%"%#)"!$%)"%#('+'#$$'+&*(("*&$!$)')!!"&&+(&!'
@r7830
TCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGAAGGTGGCA
+
F,#"+#B5%3AD1:C)2;@F6)=32;=&.=63!E??,G(8A%.
@r7831
AATGTCCTACTTCCACACCCTGCTTGCTGANGTTTGCACCGGTGTGGCT
+
0/H>&C22'@18206F,.)C:"*;,GFEC*GE"C;2@A9B)<@2493G,
@r7832
CGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCNACTCCGTGCCGCCGG
+
FGHGH</G<G17!+!:,96C<92G8ED"4);E<%#+H?>4-!(E'6'%HC8C!*H8=1;(
@r7833
TCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCACCATGGTGATGAT
+
'%1@,790*!E@8)4(/-FH9.D33@5,+?=9="E1FC:E@=5EC$!)0*?.'<=;92
@r7834
GCTNNAATCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATTTTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCACGGCAGCAATCAGGATTGCAATCATNGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGA
+
(%'&$#(+)*&"*$!(!+!%!'*!'(*%)"""+!'#"*#"+!)*('&#)''*"+*!%%'((&*%!%+$&$'*#*&(%&$$$%%"(+&$$!%$+&)++")'*)%&)+'!!&*%%(+&#!("*%)(*%#+'+*#$#%(%('+"(#+"""*$((")!%$$*))*%!#()+$$'!$'$!$)#$%
@r7835
GGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTATCAACTATCTGATGCAATTTGCAC
+
>6%.?-"9<90+#"?/#43%1"%2<<-:?D?37.=6%E13,4=,F"*$0'-1&95(B$-0/H*"
@r7836
NNATNAANCNAGTNAGNNNCNCTTNGTCNCNNCNATGNGNAGCNCNNNGCNGNCNNNTNNCTNNA
+
"!!!!#$#$$#$#$$"$!#"#$"$!"$"!$#$""#"!#$!$$!"#$$!$##"#$!""$!$$"!!#
@r7837
TGAGAACNTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGNTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGTGTTTGTTTGC
+
4?02=B2:$<?G6:$H=;6%4!%(B#??7*D+!HD5>4-D3":88);=>@+!<,FA8F%G8!(9-<5-;D&E@$<"8?037A113:2&>E=5D:E<.B907GGDB!%GHC!-&AE:92!;6;)@&8C2+8$1H2$=9+D!?.,1A=?
@r7838
AAACGTCACAACGTCTCACATTAAATTTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATNACATTTCAGCAATACAGGGAAAATCTTGCTAAAACAAGAGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATACATTACTAAGAGCA
+
G0E2'@-C<4?(!*&052,3%#!EF:*4G'"96D*@#!B**56'9;.4*>:",!1&*2>A2:C;-5/"/>223$3'9A@;2%1%FF(..:/F'H!-)8:C:!EE76*;/BG-B/F=:*?'/GD&01.14G%35*G2;D/6-D-A08!2@"8F1.:,8)4$B=5:2,6;/0.E03B+"F.6D6&3*6;HB-6((5$(<6(D?GC)">2+#0=4:;7,18EHEC.E371.B?46>%$4?D8DH);<7;$D,*D+!%:@"#F32H,@B>HH'4'5F2%>-!.33.;51:4BD1C
@r7839
GCAATGGCAGCATCGAACAGGTTATCCGANGGCAAGNGAAATCAGCCACAGCGCCTCCCGTTCTTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGTCACGAAACGCCGTTCCCGGCAGCACAAATACCACAGGTTCATCCCTCGTGGCGTGAAGTGCATCAGTATGCAGCT
+
@+0$(EDHE@AEE+;:6."8&+H7("6*DD7?4%'A'2(-!--"G&4B;F91#,F"+'%,5',3?HG0%C4/9.@H@#<;&7;&),G=E:A!1$06=>99?(7A@A%.D<+/>8EG&.?;35$#E5GF8F5F&99);BA>#3@(65<0+9&>/"@+D%-(8:9"'-!#G%ABE8@!?0*81G,6@=E+."0
@r7840
GNCGCNTTNNGNTTCNCAGGTGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGGAGACAAAAATCACCTTGCGCTAATGCTCNGTTACAGGTNACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATNCAAAATCTAATTTACTATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAAGTTGGCATTATAGAAAAGCATTGCTTATCAATTTGTTGC
+
'*#(($'#$$%"&#($)"*(')))&+(%)!%&!%%*(%#!)"%%(%!%+&)"&%*&$$)+#'$*!!+*&'&&*%$&"&')!"!*)+#$&$!!*%'&'+(!'&+*"*$$*&*'+"'(($!'&)#)))&!%#&&)&&!'&"++!""'&&#%*$$$+*)&*'+'%)!%*"'")(%%++!!)!('&++'#('!#(&&**)(+#"!""+")!##*&+#$#%*'"(+''%*'+!%&''%&&)*"#'#*%%'+$%"($'+*+"($"+&%*&'(!)*$*#"+%*)!+*
@r7841
TGNATCCCNGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCT
+
"$'$)#&)!+")#!!#'*!)*#')%!!(+**&"!$*%#+"'$#%('*'"#&+!(($%*%&")!"#*$
@r7842
GCAACTAATTCAGTCCAGTAAATATCCTCAATAGGGAATAATATATGCTTTCCATTCCATC
+
/,HC(*?"=C-6B4&5',(+7(37G")6G*;;=#:5-%D@058'CH$B55A3!D@8B>H>D
@r7843
NTNGNGGNNGNTNCNGNATCTNTCAANAGNCGTCATTATGACAAATACAGCAAAAATACTCAACTTCGGCAGANGTAACTTTGCCGGACAGGAGCGTAATGTGGCAGANCTCGATGATGGTTACGCCAGACTATCAAATATGCNGCTTGAGGCTTATTCGGGCGCAGATCTGACCAAGCGACANTTTAAAGTGCTGCTTGCCATTCTGCGTAAAACCTATGGGTGGAATAAACCAA
+
"('*''%(##('#('%&)'(#"$%$(#%'#*'+&"'(&*!+*!"!+)(+$+'$#)&*#'#'()*(*#%%%(*$%!++#+))%!#$(*!+')%)##'+#"*&(+$)&$$($")#(!*$$'&)"+!"*&&&$!*+!"$)$($"$!(+*"!!#$)&'#%!("&"$*!*%$"*"%%**$#$#%+*+'!%"&+%%''$+("%#%$+$"*$+$+))#"&(""+$%((+&&%"!'##'*!"&%
@r7844
CGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGC
+
908H:D=A=/%#A1";3<:,'5EE$0:A>%1#!D7F>6B2$9=#34$.#(1C4F2GH*<@*$=G(<)6$<#8-$"B!DBG0H6>31A=)F?D',2&=B8"H.D.A2:)/8G1-';4648)9B3)!-;"54C7:DF-H&@8=D,),.03&>4$"<48+?"73.<A1>=<;>59'>>"=$&#E7G(035#FC#-H4/;=/F6
@r7845
CCAGTTCGTCGCGGCTTTTCCGGACACAGTTCCGGATGGTCAGCCCGAAGCGCAT
+
.):$0/$1&+;<'2&9E5.@1+E9F-D!'+24?3:5(HDA=7)E-!&&(##(/1D
@r7846
GCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGANTTCATTAGTAAT
+
7'.2AA64+8)@@./3H4F(EG!!;,?8+2E4("=3,@3.$5+-1$FE(2C8
@r7847
TGCGATGAACTGCGCATCGCTGGCATCACCTTTAAATGCCGTCTGGCGAAGAGTGGTG
+
F3*0#"*).9:2=8;6"5?0&/<0B619+/@9%;G-,*0.%$F)A9!-)H/%,*&=--
@r7848
CTGCAAACATCGACCGTCTGCGCTTTACCTTCGTTNTACAGGCACTGGTGGAAACCACCTC
+
BA)G?CF2E;A#'F"AH&%&&DA-/:CB#<*@H%=":89?!A$F)484(,3F/?>?+F><+
@r7849
GTATCCCATTCAGGGGAGCNGTTTTGAACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATGGTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTNAACGGAAACAGTTACGCCGATCCGGAGCAGGAG
+
59)B6*4*,+7>8?.<1;3C>!*"96*%?#DA?=?.11=<3E09G/8>3..,E$1D2=1+D0CA>%E.>>5*A%A'=1F@<;64;H2A-(0!D+=9"94"G)/&-/%=!(55,.'AH?$#!@:-/%?-!E7$4FH*@!9H&BD:51H*D:C1/>6@,4%5C:.8C.-47)C4"-F'G55HD"8,'.-(G9;.,(,<H*#(9#>.)E9539C?G+#0F
@r7850
TCGCGATAGATGATCGGGGATTCAGTAACATTCACNCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCCCAGGCCAGTGCTTTAGCGTTAACTTC
+
6")@%(,,63&)23&4;:1;3C&:2&GF!*AD8ED#''5<F7=14H1(;5(EE)3/FD?1$/G=<3=A?=E50D&'&7'-)8$B:&>A133G-589FD0*1*3,.2&'$4A#5
@r7851
TCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGTAGTGGTGGAAACCGCATTCTGTACATTCGTGCTGTCGCGGATCGCAGGTGA
+
DF<"D"))=G!=H$161!.D1.!"9'<9B/B?'-)60>H-6@%8;".>5E58H'?3=+/"('<G-:;BBFG,C)G4%F8C:1+1$$CA2B2=2G%9:)>*F"-D:FH3D=%
@r7852
ACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACG
+
,34((EC@"825D:A,)%;4$E8>*1'2>8&)'=F7"E+)(37@/9ED-%*D>,&83H5?9
@r7853
TAACNNCACNGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCANTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGATCCAG
+
!!$)!"!%*%+(#($&#"+*''")$)&)'&)"*)")(!&%'%!(+$+((*$*#)*$&'"$(#$#+%&*)'(#!($$)&$)""$%$%&+"(!%)'""'$+&$!()!&'&#)+!&$!&+')**"$%)('!"$"&$()%((#!')"&%*"+!""$*%+#+!&%('#%+%
@r7854
CCAGGCATGATTCTGTTCCGCATAATTACTCCTGATNATTAATCCTTAANTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTA
+
$@!$"7@#:BC5?1('"0+'(D0C?/3F&#H.:G8.=826E'7,G4#E6.40*)?*=%B<17;9/<*?8EH93@2&7<;')2F0,,G<8&";*FE#,;A'2$8,>&@&+?.1>3%86>%;/@;F526EB7G-5%$06778@C210E/3$114.#=,*=&G2>815"9H?0/&2=#)!C>+;."F/H#+G9G-DFA<
@r7855
AGATGGCCTTTTTCTGAAAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCC
+
6H"%?'!;*$+'F8#=+&FC,?/:B0,3<.A%6H;=4$+0F+C;1'F9D=2H:%>H$&5&
@r7856
ACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTC
+
&$96>=;#?)9.2D4E2(B3069$EB1,;$H3'&@6,H35+
@r7857
TGCGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGNAAGTGGCAATCCGGTCAGCNTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTNCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGGGAACGACGACGGCACGTATGCCANCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGNCCGCACTTTGACGGCGAACAGAGTGGNACGGTGAATNGTGTCACGCCGCCAGCGGTGCAGCN
+
7C;"01-83?AA/-1@H$+=:?H@/8&*4754&D9F4BA:=2?,555(&;H%?.1"=34#%9EC285>*$+)6/?(B>2,G';6!),D'5"!6+50"B$$(A:D@5G9"#*?H+B%,<4<""%<#+:E%:?G.#@6F&;AH/)CB(6%4CED+@GEC)H-#6A>#E=,6"1!%/8&>"098<5)#+<H9/!'6F*A"DG$9*1="@'?+=!&C)@>7HC6D'-H@:''5%D'$>#0/E#%)B!-D0,"B96@!"5'/6&15HG/%5@5"06#:2&5;$64G-@?4+4<)(="6;!*8B+F?.E0>7$8/CC99@A@"6A2&>"C"&-D/<@CF<6F,;/10<C1937#%":/9=@;7C?C;2D?<DGE>DD=F57CG<D,E%G"E(H16."71E3),BGHA&>7EE+1B;$5&.F+>:+)?D6<<
@r7858
GNCCGTGCGTGTTGACTATGTTACCTCTGGCGGTGATAATGGTTGCNTGTACTAAGGAGGTTGTATGG
+
!!B#&1/F'3BD+<EB-C!/<:2++2D,C8*!"1%/;(!A'$3@(4506>-77-*0+,$=&$??>/34
@r7859
TCGTTTGATTACGGGACGAAAACAACAGGCNGTTTCGATT
+
E34$=?D+"!6&*./8"");A?0;?8E760.+'"$!&6<(
@r7860
GTATGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACATTTA
+
5$+C6#A=*/FD6#A&>1C1E?B.D#7G!<@DA";A>"*9%CCB??D0
@r7861
GCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAAC
+
7";*40G:H<#3((E,*106B@21FED%2:%2B-99D'4=8C0>44#
@r7862
GGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCT
+
'/5?:)-0$A@65:*/8%%.1.D3A*H0FF&5DA/4'88-#!F'#0>:B"4D:/$.'?4D!=6?D.;'2&?C/>(@?5?!.49@,!D11B-F&C4.H);'0@&CB
@r7863
CTTAACAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTTATTTTAATAAAATTAAGGGTTACTATATGTTGGAGTTTAGTGCTATTGAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACNAGCAGATGGTTGGAATGACTATTC
+
+)%:;%7<?E*:%;28H==$++B&DB+/@4-?5'%,(B5)0@@7(B;,6%+7.;!94G)4-G,C-E0*;9B)H&B#+H3%1D.HH7H#D2.;@CD+628)**F6F?G1#.&E252D><3DE%*@C%6@;C,/#,<DC3>H<#98400"=7/7-E1)"#4C+H(@
@r7864
CTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATG
+
2H>6-85A79%'@F@<5764728")<;*/A'-B@.F:<>((DHCE)(D1H<9-G"*/?6(6.)4':H=#<&CH
@r7865
AGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATNTCTGAAAATGGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACTATTTCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGC
+
$;E,7F*A4>"@$)01C+.5@G3=!3((;=#<-6ED"55(!/"3D2@H=&4?*=D;;?*H@6-H:F*,G':DB%H"9!$,57E)0@C,,8'43<3:A="3:=3B(88/.%7,%$&=E4"89H*,"05AB)#.+*2F%799G+@/?99;E2B*','+##=54B=*?&A9,F">#E:#.4+2.!<?F6;4(D'36,8E)F$29,$-?>:A45+6A--3E0F7/G2/??.:$:&EE<1'45!+?
@r7866
AGTGAGGGCAACGGCCTTGAACTGAAATGCCCGTTTACCTCCCGG
+
8#$3>H79+;<&+0>9$=E.6FC72B=G7/%)8B=#GC<,D1)-G
@r7867
GGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCGGGTGACTCACTGAA
+
*;9H#A,:/G49-()*0)4-9+(,32&B#-3-B-H68B60+G"*<DC(HB5G.107-4.;C'9-A/D<,F0FAH<5CC0>;;10$8#4C46178F8!=ACDF+33E+C.
@r7868
AGGACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGNATACAGGTTGTGAACATCCANTNACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGNATATACCGCTCACCGTATTGCCGGTTGATATCAACC
+
+"*".5832>G'3EB$.CF'6(6;9A'@A7B88#;(30":%+H.DE%/';=A&-*=$!,9$A..1&4+H+"4)2&,="6C5<))&2&)A0+;"=,5()1G/5GB9&;F.G?H-2*-;&AH%1H;>G&613FD4AD4G,F4-*>?;#C"-=F->?E@F,)HG#3>F(82?8#B
@r7869
CATCTGNCTATCAGNTCNTGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACACGCAT
+
$*$(&)!(&#)$$(&&)'"*+$!#(!+"+'$("#)+#%%#(#&+$!"$()"&*!)***#!$#$#%%'(("+$&%#)'!$!'$#&*(!$*!&!%$!%)'+")&%(#!*#%')%%
@r7870
TCACCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGAGCCAAGTTGCTGCGTTTCTCACCAATAAAAAAC
+
#=.>?FH@<(2+5#%:5C4-=DH@%C>F-2>,((1B+?(-D?H$6*F739/&B(!!E@:"'B2(8>E#2:E%$8=#"7C(A!2GH+5/A%+%EC*/2E$%8!?>:>*+A3$35+47ED!+5@06C!&BD
@r7871
CTTTCAGACGTTGACTGGTCGCGTCTGGCAAAAGNTAAAGACCTGACGCCCGGCGAACTGACCGCTGAGTCCTATGACGACANCTA
+
":D9%;;0689*,=$'*H@G5(%F%%$8<E.('7E$D.BA=5C&1!4C9,!86E+9;F"/2G/9(89&=&=;$(@/(+;<935<5#
@r7872
TTTCGTAATAGCGCATCTCTTTCACTCCAGCCGCGATGAACCATGAGAACGTCGTTGACG
+
,2$A>9-!&G20,"675H#"?*GG<,(D)&E6)#D'EF169&<7(.%;!%D/A9=%6(55
@r7873
TATCTTGGTACGGCGCTGTACTGGATANCCGCCAGTATCAATATCAAACCGGG
+
8#E>8A5C<&'%8,-)A<E#-2<)(=+(F!$+D7F.$&A##':-*A'-G=E)#
@r7874
TCATTCGCCATCCTGAGAGACGGGATTTACGTGCATNCAGTGCATCACGCATGAC
+
8%3#"-?(-3"?/%/;&849$'9D&*;5%#/:F<BD*'7,"2$>A+*4%A,6:"8
@r7875
CAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATT
+
C&'<583%#:1#,*/"/8@*56+99F(>62*-$#'$F77DC-+010+A
@r7876
ATCATCTGANACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTA
+
A774BBC('28#9E*C#>$?"%?@>G<*>%B.9FG%85F('3$FG6'<7&%=%C'?E'H45HD*>G#7C7
@r7877
CGCCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACC
+
)*+&()'$"$(%()("+$+%!#'""%!%(#%)&!(!%&%")%''
@r7878
TTCTGCCGCNGTTGCCGAGGAAGCTGCACGNCCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGC
+
3+9;D":9&HAC#8-C)/#+E&:"!<<!(DB0-4;0?5%.<D&7<HE/21@/35:!/,4?<5<:=B'&A%!/D.D>2#=-"#@+77@DH-B3E-218.9*;0E,+E"=@,,*<%+DHF#@D!.!$E5&@B217F.9D6H8+CHD)<=+/)@30
@r7879
GCTGGATCNCAGTGCGCTGCTGGCGAGCCTGCAGGAAGAGGATGGTGCAGCAANCAACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGGCGCTGCCCGTTCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAACAGTGCAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTTCCGTGTCTGACCTGAAAAAATATATTGCAGAGCTGGAAGTGCAGACCGGCATGACACAGCGACGCAGGGGACCTGCAGGATTTTATGTATGAAAACGCCCACCA
+
'(+$#)'$*(#!&%%+(#&"%$!%'&**$"!%)!(&&!&!')$*!+)%($'"!&&)#$'&*#*'"&&+'%'*($!'%'()''()&'")''$$"((!$!#&%$)!#(**)"&$%$(#$$((+##"(#$!$%(&!+!'('""**++'##$#("#$+!$&)##)"'#$("+(((#+&'&%$!*))##$&(%!'(!(!#!&"!%$%'&"(#!#++&'$%*(")$'!((%$%*!"*+'!'#+%)!%"'"&$%%%%$'&!&$')%&"#'*"%*"&%)++)$#&!$*!+*)!"'(&$'*"&#)"(%)(#&''$&&(')%#(+$'&#%"*("
@r7880
CAGTTATTTACCTACGACAGGACACACCNTCTTGAGCCTACAACCTNAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCGT
+
2'-.G/99F&-@=(F%;&@5@*2DC&:'?%AC&+A49"717AE)5C3A/7&.BA?H5=+5?$%?6CE,0CC=,!<493FA6!-(5G0
@r7881
NAGTCCTANCCGNTNCCACANANANGCCTTTTATCCACATCCGCCGCACCAAGACGTTTCCCCATGCCGTNGCGCGGANGGGTCAGCATATC
+
!"%)$#%"&&'&(*#"&"('!'%$"#&*&+"+%"&'%))"*%)"'"!''$"+#%!$%(!"!''*!'&"'&)(!&%''+%*'+*!&!+()+)&
@r7882
AGCANNTGCTCNNTGATTGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGAT
+
(*(&$$$#'"'&!%&'+)('$('%++!$%(%#!)"'%)$%*#%%%&)$*#)#+#"%)*$)$&'(&+)'%'%'*
@r7883
ACAGCATTTAATACAGAGCCGTGTTTATTGAGTCGGTATTCAGAGTCTGACCAGAAATTATTAATCTGGTG
+
G%$>8=,4H%)=A&0%E&#/5?&&57/9<G*%3'73;*B4$(H2+>@C@+++#$FHE:3?!8<0+5<4G2F
@r7884
CGCAATGCTTGGAACTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGACATGGCTCGATTGGCGCGCC
+
?-;2G>+9',&,@=>58>>0H'A;D>'7C1%3E5((4EC6#"DB>-,47"@E%!>$B$>CB%E"=9"*!+(>-4>?6=(F/9*:1<+FCC)A4<E"61=BC&-60'!=B/<!"A<7(;G+8>C%;84<AC<A*;!(<=@6DG5=2@,284A?C->
@r7885
TTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTTATTGTCTATTGTATCATGCTAA
+
70+D3.&7!?B<)G,*3C?,<C1%;5!71E99H9*EDA.!C$/;G&AA94AH*,-((C'D?/'(3D$C2
@r7886
AGGATTTTATGTATGAAAACGCCCACCATTCCCACCCTTCTGGGGCCGGACGGCATGACATCGCTGCGCGAATATGCCGG
+
:-5-(%8)>#@5:8"$B"G>=(3@:>=>A$#A2!/15F7#>*-)%(A9/(-:B=H)!.'4=B:1C98("8%+6"-=/H>$
@r7887
TTCTTTAATCTCGATTACGACAAAGAAATTCTGGNTAAAGCTCTTGCCCATAAAGCAGATGATTAATCATCGAACTGGTNAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAANACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAA
+
@C$)'G8.6H%+4@3?/CA6-D?#E@!%:5D<$=(3258&'B)4/"#(.D6:5C&=(6*+2.04A#D15).E03*3GE+66#0.E#A"1,#!0/H1F&0&'77154A1*>(?)1?H.)@D"FG*59$H8?2:'>.>D#:H$C*B>!(;ED9=%='H)>2-12!!G(05D'")*"H)=7#-.G
@r7888
CCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTGTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATCATCGCAGATTACAATAACATCGCCCGGTACATGGCAAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGT
+
#0F7E55@%3$<A,/:")HA693E0GA1"#9!@G)(89$:AA*02F5BD/>2H)7"&2;F9*)!=>F:3###;0>@>!@<1.A07!*(85!)C;>&H:B)>E?&2?DD%E5,A%>0A20,0G:::;D(6H!0A)61)B;,H-'5C397*;;>)#G;-67<()A=BAAEEE?2;@++<"(F=-"$D(4@#!(61$07(37?>/5G,H)D:&H-F7#&*
@r7889
ACTGTGAGCCACTCCGGCCATGGCGTACGCACTGACCTGCTTACTGATTTGTAAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCAGGCTCTCATAGTGAAACGTATCCTCCCCGGTC
+
EC6"#'DB$B2?;,F"E-)C5>-3<5H/7D4=(38!G-CCF<'94C"<+B(9.E)@><A@C8153;C0C<#+'3>1;0=!A@#,@)+:0;5>+>>#:A$%'D0CB30&0E,:*&9!#6),9>(1
@r7890
ATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCA
+
))3F/F@@-D746@D!8;&G<>*/A*HH8C/6#96;,C=1<2>0*.5=C";?D8D$@CA!&$4?,)(5@4"C:G2E4
@r7891
GCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATGTCGGACGGAACGTTTAAACCGGCATACAGCAACAACATG
+
3@$*,;=0:E)5.3D%A=>A%!$@-/%G0D;/7/-H67CAC/84>2>F*76!9+H2)76$0,:6(9'%D,'F5&;D+6;E<8*)1%)3
@r7892
GTATTGTTCGGGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGTTAAACGTGCGTTTTCGCTCAACGTCAATG
+
474B7$CD.=G7@)?$@5?@E@,;&>;-F;20C73<@/;*7%%=8;)15+$20=+<&(DD8.F5BD6)AEB(7A1.DE?)5,$/1?BG5?';@;454.D,7@9EGF+9'D6C+,6DD)E86":?G:.%E)H;@<:/'!<:=<H/C+@+*1D9!(B6(1-E:@5;8,-'.H><')
@r7893
TCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGAAGGGGACGGTGGTCAGGTTGTGGTGATTGGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGCNGGCGGTTTTGTCATTTATGGAGCGTGAGGA
+
B?!H@A!%+!5(1G=*)"?&$.!5#9,7F@2;?E3&.3/157D)A,8'0'>&>)4G7C,G)54H228"$CB+1;,+503E<)3>2<6+55:G32%9C3#$H%8+<%,&=$(83'A>E@/G3/3?5D9&9%B(B'#
@r7894
TTTCCACCATGCGATGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCG
+
#5072D0"4H(/?=H3BBB;:"3!(!,25*+;CD<)'1A//!@+5<1BD)7=9170!H,;6>/1$6>3+,=2#,)?B5B-F)+&.8
@r7895
ATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGTTTCATNGCANCGTTTGA
+
D%%&+3BBH*HE@.;8.(4=A'@BC(F.'<=EF;&?1%G9-:=0B&-5?6'AD++;,D<99?/F-#,/2(D.-G$$1$:D?1%E@:>&D+CF$9$@7;7D21!)"@*9/B*EH>E-.F(7DH-E!=8#A&>9,9&1/H?#
@r7896
TCGGAACAGCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCATCA
+
$A'$;+C:9?&9E.'>6=#5.(5G+D253(%.,,(;,>57#A/E/4;>)''AA
@r7897
ACAAACACGCCGCCGCGANCGTCGCGTAGAGAAACAGGCTCAATGGAAAGCAGCNAATCCCCTGTTGGTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTNTTCNCTCGC
+
E-3H809F#"84A:B$25D(;?F:@!#)F*8(F&4.E,4*!/;1B?-(D2C$48H7;"&A.:78G'B02F#411'+G)1$H(B*G*6F5:@,E@22?9>3D&;4$D,8<"
@r7898
AAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTT
+
8A:9E1@=?A*@<!45>56GH4*>"783D9"3B9'>,*.4A:
@r7899
ATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAAT
+
B.?HC0;?7D41824G(..&GB8%9(8>(96*<7A%-DC(9!9'5HAA*F:GFG'B"'(?&0+9C$GF!><9)4
@r7900
CTTCCATCCTTAACCGGAGGTGGGAATATCCTGCATTCCCGAACCCATCGACGANCTGTTTCAAGGCTTCTTGGACGTCGCTGCCGTGCGTTCCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACACGCAAGAAAAAACC
+
;(79B-7+()#-<C(E%CA?A?2,;*$,-?5C<"$?*(3!($4E49/;G/,)G<=A$CA(FGF9$)/G0H:+!8=6!-=59;#D=&+&:/(+E>12");H$F(=1E>A5@:;>/C$H-=;$,2HB:,34A+?1:9)5#H$FH+*73%8@=-
@r7901
ACCTCNGNACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGGGTTAAATGGTTTGNCAGAATTGTCAGATTTCCACTTTTCAT
+
&*$*&"#!+*('!)#("%*&#'+)**+"%)*$"++%#$'"*)+*%+"%&"#)#*(#$)(++!)(#%(#!*(&+'($&)#)+"&)%!$(*')##%**$
@r7902
TCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGTCTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACCTTTACG
+
6H;#7%",B=7CE8C??FA#/@'?G<6957-#:H24;.3D)&6'B7@)G3!$!H>;HH78EED04:F45F&,=;5D9<<!,5BB)<D5.#
@r7903
CCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCCCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAANTCAAATTAAACCACACCTATGGTGTATGCATTTATTTGCATACATTCAATCAATTGTTATCTAAGGAAAT
+
8E="0)/EB&2>9<-CBD$?CA4,!B2<&>/):#H4$>7A.H+4@H?@DD2==5F7;(4.4:H.&D?"E(@6197=D2"E6"D/.-FC=(99G;C%B$5GD9<:3*-23=1+C=4;:9@%F'1A:<E.12%?)?G05B@;1::#F?1).)-8HC0?6>50("<(!$E65)C71+4#)F<)$;9-@F)G","&(.%'!0!?6G:)#6D?<4B'2$G5#<*#,4'2?./'B%F?2H8/,#H:".C3((3B>.#''0*-D=;63$-+1@+H/(:#-(!$2?@E1490'$==H)9+*""=!++5.H%.;'G"/2580/$/DC8@#=F8(51<#/=H%F(,9:>E0B:/%!
@r7904
CGAATACCTGAAAATTTATCGAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTAC
+
-7,(4C$.,DDC!:D<,+2',.+5DC5.@'05'8:(B+C2B"+$4+3;8),*6%;*(".H8"6;*5."7#)(,1$B7$
@r7905
ANACCCGCCAGCGGTCGTGCTGTATTGTCTCACGAACAGGAT
+
$%#FA0$.%B62$(1,2)-!=E9"-A!@-7-?E&#*->'FG/
@r7906
TTANGANANCGTAAGGAATTATTATTATGTAAACACCAGGCATGATTCTGTTCCGCATAATTNCTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCAT
+
'$#)'"#%%+*"*)+)'"$'+!&('%+!'&&%%!'"&%'"'&!$(")*"#!!#&%)!$%"!$)!+!(!!)'%%))")$%#+"*"+'$"%!!*$''!&''%$'$$)#('%*%(%&%)!%(!()%+)%$+%*
@r7907
NGAATGTTTGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCNGCCNCAAATTTTGGCTGCATCGACAGTTTT
+
"&$++"!++$*&%()%'(%%'!!&$%'"+$'#("'+#)'&%)"*!%%$)!$!'!*%)%&*#*(**++!+$)!$
@r7908
CCCACGTTGAGCCGACTATTCGTGATATTCCGNCGCTGCTGGCGCTGGCCCCGTGGTATGGCAAAAAGCACCGGGATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGC
+
0045?H;(>6A03>18E#"(<151?1>";(HAG.<.!"&A9G-0>C@!3-?2**:B#C&*B""-8+E&'A6.D%C&3C1?;,>#$262$?2/-HH&(9&980*(.0;+H)."86#/&@=%&<.6EE1-?4'&+1FGG=+'>4<)2A:)71(*5=8A>"<4G(%D1,3/F#9C-#1
@r7909
ACATGGTTTGTTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCNCTCGTCTATGTATCCATTGAGCATTGCCGNAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTANTGCTTTAATTTTGCTCTGTAATT
+
+$&')$&#!!"+!))&#$*)+%!#'"'+'*#"'"'*'%"'%(%++*)#%)%&!$')"#(()&#!!"#)"!$)&%#'$#$*"("'$)("!")&%'*%+*#"%&#+&%!+%#"$"'(++$!&()&+#!)))#*()!!#")'(&(&+#$%(()&)($+&+#)!%!&#++'#*+)%%*$""!+##"!%$*')"!#''%&+)%'
@r7910
GCAATACAGGGAAAATCTTGCTAAAGCAGGAGTTTTCCGATGGGTTACANATA
+
E9D?;#FA8>(;D0#A*=??H5E4AF@7+9;2C*="90)'(:7A1+!0/*1&$
@r7911
CGNNNCNACAGTTTCCGGATAAAAACGTCGATGACATTTGCCGTAGNGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCAATCGGCATGTTGAACGGCGTGT
+
$)'(*''$"+!"'**!*$))*##+$#"+!'#&)(+')#*")!!'$$$+*("$%$!!!"$"*!&%$&(($%$%&)#&'&$+&$#!!)&)+'*"$'''+#$('#'$("!%)"')!'(+#&(!$$(*!!)'&%%'#+'
@r7912
ACGCCAATCCGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATNTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATG
+
H(8D;8(4H5HF2?=EC%1CDC(#H)G3-H3/'?1(D3'#F9=@"E293G8"7=8H,B%E#CH2?*#6.=*!<==@$8%5!7D@)!<@C6*6-?A;H!/3?,-79F?,;<<,%@.:19=13E'="=2(&%7FF!9$",<#DBED9*C38.C@+&5>:
@r7913
AGGATAAATGCAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTT
+
8G-815,<2G@7D""<FA65/<'".C,E'2D3GB1$>0C*%*"'09/,-!33$97&,'
@r7914
GACGTACACCGTGCTCAGCCTGTTTTTCAGCGATCCGGATATGCATCCGCTGGATTTCA
+
$G+D3+2-0=#H17:B?4F#9"%H/,A2"*6';<F.<*;BD,C"F%?4050F%97E,GB
@r7915
NCCANATTGTTCNNTGCGNAGGNNNACNNNATNCNNNNAAGANNGNNTNCNNAN
+
#"""$!$#"#"##!$$#$!###!!"$!!$!""##!"!"#"$!$#"!#"$#"#"#
@r7916
CNCCCTATTGAGGATATTTACTGGACTGGATTAGTTGCCAGCTATGATCCATATAATGTTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTT
+
)!+*&#)+)+""#((*#&$#"+())+#)$"#'%*$'$&&&&&($$$%%&!++$"+!))"!%'('%)'&%%%'%#%)*$%+)""'+($!#!'##$#$&&+%$#+#&%$!'#!
@r7917
TGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAG
+
>;!A0D;71DA8!<1$1B$FCA0C$1$=9C83=<4G%>,7>H=)6@4+#=6G++H1&$?D#H.<>B.$7.6?FGF;?(//!,)">@"#,+;%,+534"'3HE9:1:+.E?"/C+H(:)$:3=%
@r7918
TGTNGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATAATGC
+
@@<F%9!G&'=#,C.HG;&&::+&2(0A9A%,40G35F6-/4((&(7)F@%@/!!*4*&3%BA0(EH'."$C'
@r7919
TAATGTGCATCGATCATCAGCTATTGCCAGCGCCAGATATAAGCG
+
>2?>D.F%=3"0??F/#35B:H*<1AC&93BF&0:7G?A.,5B.6
@r7920
TACTGTTCCTTCAGGCGCTGTTCCGTGGCTTCCCGTTCTGCCTGCCGGTCAGTCAGCCCCCGNCTTTTCGCATCAATGG
+
="/'(6)),F,$'!&H:H!F93)"$0":&%$'A-CHF.A,@.5'C>89$<1+(:3"#BG4;&7#64-@ED"<E2:*/=7
@r7921
TATCGCGTCCAANTGATTAGCCGCATCGGGCAGGAAGCAGTAGAC
+
(H%89+7,H%"48;GH3ED'&D+?$;>9&,F(4(C:?(&E&&:(<
@r7922
ACCGNTGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCG
+
;%7A?6C0GG0("+B;1*$0".44C2A!7@;$?-HA.C*@2F+;
@r7923
TGCATCGCTCAGTGTTGATCTGATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTN
+
+!82@.-B16C@$/;1@=)2,&"74(!H"B71.4)G%?*?1*#BA);@):"2:/=4
@r7924
TAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCG
+
1B6B@,=.B;-8B/!GA411D5!AAH5AH"3*/G82,$1><<+?=!"!=$.G.H,A=;')?$9>)
@r7925
ACCAATCGAGTCAGTACCGATGTAGCCGATGAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAAAGAACCAGGCGATAATGGCGCACATCGTTGCGACGATTACT
+
2"C(-BB:C*.DE&*DB)HE%'6D%G5(C83>9#;F@H;4;2C4E<33*!H$E=H2D<*;85!-F>%G0=+>88C*-C1=7G=3')7'42>.>":C1G;8&*!>G8D(E+CG>!$"78=-!&47GE*:$:0D?
@r7926
CTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAA
+
H0.<!71)D$).(@48/0864*F::?+FB"())B3:+'H/ACAC-),<264%("!9->%,)D-)/@0
@r7927
GGCATGATATTGACTTATTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGGAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACA
+
+D>H!/A-4H@'/=8F6A'65?D/)35D#2,/*2((02/%(D&=59,C4(<)5,7?*"0C.*:)B">C@"0;@&A3.($#,A.>GF?4?0F+AB?-B':(!/4%,6+5)$!8%,H4<9*):@$A.-=;&5A/1G29447$=#:%C1@>2<A1DC0:B!</,$GHFE6>!0#2?*,"*A>D=%!$4CB.
@r7928
AAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGG
+
DD!F'/%D;81F1A"$;"<F>3C8@5=-./)=$2=A*G862/"*&<3$3)#*9.=18*AA?AE>B)8(<%B$=*C=,%/5B:?09C4?'+7::-::.#/!>':.#"<=#)D.,-+4B>#=9%,;*,
@r7929
CTGTACTGGATAGCCGCCNGTATCAATATCAAACCGGGCCATTATTA
+
)(#+'+#%)')##)+*'!&'+("%"!!$+($&'**&("+'*!#'#'&
@r7930
CATCGATGGCCATACGACCGGAGCCTATCCAGTCGCAGTTCCCCCAGGCACTGCGGGCTTCCTGAAAACTGAAGCGCGCTTTTGAAGGTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGG
+
.5&8#!AB%2(59:4#'./@>D?;'5)983E6)0+8..)<C8#99C<AB<E)E8+$6;7$7%)&3#04@0<G#:2C+2C.=-?-?D3/1+(78E,#/'6>F@B1%GB5-?$F,6'1;<5#>#"D,=.:=?F:!3*3:/(#9?.2$HA?B,FD'03$
@r7931
GAGCCGTGTAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGANTGGCTTGGGTTTATTT
+
*++"#$&+('+#%$"&"&$'(&)&+"&!)!(#)'$)(*)+)*+""&'+&)"!%&"&%*"
@r7932
ACGATGAAACCATGCAGGAGATTAACACTCTGCTGATCNCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGNCGCGACANTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAGGCTCTTGGATTCCTGAAACAGAAAGCCGCAGAGCAGA
+
>@F330'#&*+A5''32F$@F*D%4!/H1',C,C-F8>4DGB6=*96H-HD7;G9*"2'4;0%%*4&>,D,,,''D666C@)1./=66!B+35"()*1(!--#%"$('&!7)*E!87!09%DE")#!7-,,<@!D#--H*E$"D.1%H6%G3H7/HEGE;&..-81E-,;=255$2C.;5
@r7933
TTTATCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGC
+
,$=02'*0F,:/E<:.)!:7&/F474*$4;3&&E3'D":7B?:41$#!>;
@r7934
GCGGTGATAGATTTAACGTATGAGCACAAAAAAGAAACCAT
+
7#5+($"<1H:(A-#7$;9&12D43)9!/:-E<+H;+,*,)
@r7935
NGNTGCGCCTGTTAGCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCCTTGCCCGTCATACACTTGCTCCTTTCANTCCGAACTTAGCTTTGATTTCTGCGATCTTCGCCAGAGCCTGTGCACGATTTAGAGGTCTACCGCCCATGACAGGGAGTTNTTTTA
+
!D2'+C$4&))1"92+<!6C("F;)942,9F6'B#5?1G;'CD8$"*(22$567GB+/-*<F8E15DBB-,&D5&&*2().5D'?60/779,G?(6GA=:<);/1''$/@B4"!(:>;5:B0503$;F%2@/"4#CG,)4*(-*)-8H%-GCD0=B"!3EF%%;44(-F!;H2*.(9"5BGAC$45='F-
@r7936
TATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCTCTGACGGGGAACTTC
+
8.0H1)/C0,<=1&=;E7&@$?"7-BB+3G>D@6)B);BD#0BAAB$?6?)CG701F#3G/@;GH;&%3C-=63%(<5(;(+DE%C@+3=1
@r7937
NCTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAG
+
!7-C#>4>-@"#EA:!:60#?G7C"5B*H)0&@,AF>.=*:"!:8,2;,(/G='=1B++7D9!?#"9!'<,H"1E(35!<,?BC#0'A!;;5#3-F?$#-DA9!B>C$*2'
@r7938
TTTTCAGCGTCGCTTCATAATCCTTTTTCGCCGCCGCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGT
+
++*&*'('%)"$#)!(*+%$**$!&*#!+$*#"()#'*&*&%##&(*$"+(+(**("%+$%(*+'+*#"(&)$!"'#(##%(++*#$$(&)&(+'($(+&')"++#")+'#+
@r7939
CCNGCACAGTTCACCGACGTGGCCACGCAGCTTGCAGGCGGGCAAAGTCCGTGGCTGATCCTG
+
@/":HF,037F=;.,9(%&,+$@A!5++G5/44AE0BA7:HB1,/&2A=)/H(?1B;>*"C'6
@r7940
GTNGAGCCGTGTAGTTGAAGGTTTTTACGTCNGATTCTTTTGGGATTGGCTTGGGTTTATTNCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTNGGTGATACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTTCTG
+
'"!($)(&+##%%&!)$!($$'$$(!*&&&"*+*#(('((*($*&''(%)%*&#!"!+)&'$+)*&%'!'("%$*$*+$*&+($%#%&#()('+!$$#$&"*$(+)))!!$)&&#%*!$!%+)!**!(*(("%#$)$'$*!*!*$)$$$$$!&
@r7941
AATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGNTATCTGATTCCAGGCTTTGGCTT
+
:>5E7GB<,6!G4(@;4$3CG/H,AF?(7=B/,0)3"6+$2;H8)'C$>@((;*+$,F%!:;3,6:4;7+(2;=&9=@-0"),6A-
@r7942
GCNTCCCGAAGGCTTCAGCGACCTTGGCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACACTGGCTGATGGACGCAATCTGAGCCTCACCGCTTANCCCNGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCTGC
+
11E1>#HH59HA**!@2(F+$.+9>/-56?B93&)8=C(B)D0A-H352027B>9H)555GH5+99B=G@9E4':85::/--!;47,1!;?9F1A72#>+%-"B$@G/B7>7<9*C/A3D&5#22D#G,%A1#*",8@E?,B5A-$#G2.-<?%5<#!3/#5.361E/>97;
@r7943
AACGCCTTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGACGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAANGTACGCCATTGCAAACGAAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCNAGAATGGCGGCCAACAGGTCA
+
B6*D3#G895#6")-!3;.3-0>4+6#(G%*=;A+"0/1$1+(F30/<H=07)E-1=8H!/+%8:F+:)4!>'6-?*C'/=:HG<;;=(#HFF.#<5D2H.*02E7&%%9*>CCA-6>+;((73@98=:6!%*(*".02%',.A8"'7-1$&*9C2@5D#!#F.H*>(E,#H.3.6<%D1)=,-<G2$6<)*32<?-6H6E@=(4.HCG>F@=D(;5-C1B<3?=&&;;.(EE70"H:B!3!E:DG(%%?2E%!(86B4$A4G8%G8E7EAE/=($$EGEAD7@-"3"A3'3B7":#1E.E(+A?>#C,&9/22/:@'1
@r7944
TGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGA
+
=5&)#A3:%A"$$ADE<?1*'FE<1E@2+-;B+8B7:9:C272">D6$,':'?5"4
@r7945
AATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCAAC
+
A/9G55B18@>C,"-66=)CD5,3-:2H2<1"-B6#D!80A$FH762;(&7@7A56<!-,A@,;B/E+?@'8HED4C0CH!B!-6=)
@r7946
GNTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGGTTACCGCAGCATTAAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATA
+
!"&+%))'*))"'$#"*(#*$('#$!*+$!*'!&$!#"(!"'###+"%**'$"!+%&"$+&$(*$&$%"'#$*%+!%"+)(**&##*+(&$*'!#")+*)&'%$+#''(!)*$(&
@r7947
CTTCAAGAACTAATAAGCCGATAGATAGCCACGGACTTCGNAGCCATTTTTCATAAGTGTTAANTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGGAAAGGTATGCATGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAA
+
#7EGBA"("'G'0,1';<E5;5G".1%("*43,);8#';*?F$?/?CF>3D)?3H'<"'?;-6*@6@$:F<)#=($8;D)H0:?1)?)=:)G"=9@&3,-:*2)%%-/2C2=<>/C<D14H,?3D$9<40<+B@*'22,68(G%8#2;:F$!
@r7948
AGCAACCCGAACAATACCGGCGACAGCCGGAACTGCCGTGCCGGTGAGC
+
E@&D+E%3*0H)!;%3$/C=75%!1-7.4*#5FB+/D/.F8E9FD4=6A
@r7949
ATTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGA
+
%::#!A7G::+7@#'0A6>=,#5#,)G,2>)H3GD1-B68+<.H1E3'+-BD2,
@r7950
TTTGCACGTATTGCCGCCGCTTCTGCCGCACTTTTGCTCTGCGAT
+
85)D8'3A*;%"0HG*;!03+)/A'&)D>+4?3)?BB?*:D5:0/
@r7951
CCGAAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATGCGCGTGGGGTCACGCGTGGTTTCTCAGGAGATCAGCACGGCAGACGCAG
+
<@,-<!3%$4#42!4C5B!>.C"50@;;@/7%0A5=AHB3B(=491.$H9A5#:82(%+1C*/=>1;+B49A080.$!9($@4();?*(9C,3;-(AA??>>)6!1;:65-!C8D9#7=E>06?*$$C%@5CF+&?-"9A5'(!@:AF%AF-DH?!E5F)2A'1,6H%D
@r7952
CATATATGAATGAACGCTGCAGAGGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTAATCTTGGCCAGTCGGCGCGTTCTGCTTCC
+
DE1E*=836F>++>E>"C5!%DF"F?C7A&=BG<8%.0)?F!H!1?9)A.F&H90B-.,&>).6B+@6H&>!G<DBE8A196-"@A9@>.-#2<B+?%7D%'DGD09$3G2HB35C@E%61;?#E=C4:5CH$EA<C:)*.3#F+7$F%#?:<6BD!1H>C*6*#73>#64!/3'2>+;6,BD:E$51>'-GH"
@r7953
TATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGT
+
32H;&D3+"G/@'/F;2.9??H..<<5-""?)"CH.9+:7+90!&+"?"&.@D866"/=9/-53A83=!/7:>G@2<'!>B-20A2$,6@&/AA.3"$#@&7A*10EB-F+6%%DE:+?8:#8&)6&FG6>"0A18G15C,=#G!!H;<1)*)0$-
@r7954
GGCCTGAAGAGCTAATCGTTCGGCGATACTATANATGCATNAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGGATAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAAATATGGAAAACTNC
+
"@63'A5CF//6'@3#7!DC(!).&F3&4.$B=D"A<';$?'3%&A%$9&/)*(;7+E((/9A)7E:7(>AC259>:(#38E2$%0FC$2927*?-8(''@7%,<?:-&,3/"?:(&!A+B=+6:&01:H(G2H$*
@r7955
NGTAATAGANTTTTNTGTGNNTNACNNGGNNNANCCNNCTNNTNTNGGCANNCCANNCCNTNTANCNCTCGNNGNGTNTCNNGNNC
+
!$!#$$!!$"$"$"!#$!!"$$#!$!#"$"#""!###$#$""##$"!"##$!#!"""#!!#$#!$"""##$""$!!#""#"$""##
@r7956
GANNATGCNTCNTCGNCATTNCNNNNCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTT
+
*("''#%*'"##))*"$&%'$$!#%!+*)'+!!))&**!)&'(%!$""'#(%$((($++&%&(+)'&#
@r7957
AGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGA
+
0*><CF$,6!@F*2!905#H$$$8E&!56>6%=016F2",-A.
@r7958
CGTCTGTTGAGCACATCCTGTAATAAGCAGGGCCAGCGCAGTAGCGAGTTGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTAAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAAT
+
9$'-<-:7:G0'?-/*A44+@#-')?<F!9?,4F@2!D4=)8@9,@6E=F9/!,!"AF$?"%;426?$""=$7)#E?-$.>6**0=9BE1;D="H5:!!$&C0-<:>7?;@B6%<-B9G*"5=5!$"/4<:G3,&=.HC%B*%0+8"(>*$01<,(-9=B1F83G>#8
@r7959
GTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCT
+
*A/#EA&H!#;8(-4HC1FB+A:-.;.'8">%&")"6HBH@#:
@r7960
GCTTGCGGGTAAANAACCGAAGAATGCGACACTGACGGCGCNGG
+
8%C%:-!5,##&F71D'3>=#=03#"*=+5-H!;<8-1DG"3*"
@r7961
TCATTCAGTGTTTCCTGCCGGATNTCCTGCATCAGTTCANCA
+
729C=*'$:@<8D4F4C#/-=A:8/%;<E";7/:&@=8C4<6
@r7962
GNGNNATCCNNGCTCNANAAGNTCACAACGTGATAGCNAAACC
+
&'$%&'((%"(*(&'%%!'(%"+$"*"*&(!+")'')$$&+!%
@r7963
CGGTCAGCATCGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCT
+
/%?04$C7"B%)*(+7<DA#%14#',9*$!?8'A'H7:3@!+D?*(,7=<8%9<E22B$88#"B*8H5(<>@+(24'8>25."/!2D8>3*D
@r7964
TGNNCNGTGAAGTTGAAGGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTNTGGTNCNTTTCGTTGNAAGGTA
+
(("#)"'$*!*+)(*+!&!+++&++$&&("(!(#&(#)%(+*+"(#%%$&&)&*+!&'#!#(!$(+"%'%$)**$)$#($#%'
@r7965
GAGCTCTTCATCATTTCAAGCTATTAAATATTGNTAACAGGTANCGTTTGGAGGCAGGGAAGCANTTGAGTGAAGTGATT
+
':853=->%?6%C1(4+24,$2$D(F?:$13DA)1E,)/AEGH,C8?-FGBC$;5'EH+3/C/4->H0FB;H."2D1!3A
@r7966
GGCATTGCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCC
+
A&E2:',4B!;E!9?03.".,&+DG'%)E+@*2-:0"!)2,9$0?$AG6EE?.A'CB,"%97<67EH5'C.:@*;$//2-B+.G9991.9#<+
@r7967
CNGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCNGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCNGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTT
+
*<G;F,5059C<'#HG9B4!7*@!7;*?6D.@$8;/(C@.:6"+2>D+?&,:6;,=+(=?'*..4=9!"'4C??@,%"7$&F0A,3'"B4$=56>GF56.4@E:<8'?(6&4B'2=$?21).".)6?-3(0;:($?2D+H#5"!-)F&3<1C=)B-D96:.&(("'2?H3-->-71?!F#F15E"F,2>55(#-GF:>1@F<G!
@r7968
ACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCNTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATNATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAAGGC
+
58?/'$):<.9B-/%60*./F@*#5B;**5CH=GD.23?#07F-F7)40!;0;$-(47.44'-!/<3F=A*/F@E>4<2E(A!.+20&:?'AF!%6B:D:;E049%3.G7,D#-!40D*9(5.=B5'%-<.5=7+%-8:G<#(9#-(!<?0(<DF&5#F1C67"6#F>=$B(@6,#?'%<4><=+>;;4F'!<-7097/G?6!.*!.4'#0G=79.3A
@r7969
ANGAATGAACGATGCAGAGGCAATGCCGNTGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAANGCTCCAAGCTCAACAAAACTAAGGGCATAGACAATAACTACCGATGTCATATACCCATACTCTCTA
+
'+"'(#)%'"%$&)&*#%**''%!*)!*&)%+(#'"&'$#&%##*#$)!**!("$(*)*("#'"$*'&#(&%%&%**!'!%*!)##"+)'!)$"$%!$)#('**#''%+*!!$+'!("'+!(!#'!!%&$$*#$*+!"!#&%)"+"(%+*&$#&*&$"(#
@r7970
TGNACCCCGNTGGCAAATCGGCATTCGCGGAGGCCGTCGGTCGGGC
+
&*!&)!&!&!((+%%"%%%&#(+&'**##+''++!)(#&$"%)((+
@r7971
GAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACG
+
+#25?BF/3$.958>=D#F6)+CG&,<G4DD:'5;B<34+F96C@7?($88
@r7972
CTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACC
+
H+*4/"%;*?DH)6@/'HD990,)62".(3<0A-,:B1--=:H2>,;GE(58)#4B50:H
@r7973
NGNNAGCGNGCNNNNGTCANGCTGAGCCTGTTTCTGCGGGAANGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCCTGCCGGGATGTCATCCGCGGAGTATGCCGACTGGCACCGCTTTTACAGTACCCATTATTTTCATGATGTTCTGCTG
+
")#""%()$"'))!#*'%"#*%"+&%*$$(+*("!%*))")$"(+((!'%'#'*&$%!#%))&)%+&#("+!'('%#"$(#&)*''(+'%'!'$)$#%%#++#!)#(+!$(!!"*$$*&))#)&&$")"$#"($+!'#""&(+#$'$((""%#%'++(#&&%%**$')+$(*#+##*+)$#)($*'#((+(")
@r7974
GCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGAATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAANCGCTCAATAAACCTGTCTGTTTTCCTTAATTCTCTGCTGGCTGAT
+
>"*9,3+%A9C17.H#0(>)@+>A3+1@D>?15/:3@#+D+<.%.$H>""46;<#3(5&D*A.5(.5CC+@'?/$#:.A91#,>-1@?(==G$45&$A7")+,*G;07923DE.HF;F%>-#CD=;*1;;3'>=:*#B@A1%?('"$8+65?:-,$B8'!E71>E@&4-%&8D1-*#))64:D!
@r7975
GCTNACTGGTNGTNAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTAT
+
*%)"$$'#*(!)%!+&#&+("*&(#%*%+(+$*'*)#(+!#%%+)!'!$++"*"+)*!%%*"!%'')+(+)$"))#'(%&&
@r7976
GAAACCACCTCAAAGGGTGACAGGAATCCGTCGGAAGTCCGCCTGCTGGTTCAG
+
-%H7G535#:'389"%?EDA=<4)+-!#7C-2F.49*+GF1!0!.H(65!"@"9
@r7977
AAGCTAATTTCGGACTGANAGGAGCAAGTGTATGACGGGCAAAGAGGCNATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGA
+
:G9%67<&F:G?1F7=<G@G4>*A;;EE./H8#.<C3)5E@(#45,94C/*:A8%EE:E'E.;1"H%B*B/)'"?"9F4=;<G5#30:D<E3(
@r7978
AGATAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGCCCGGCTTCATCCGGATTCTCTGNGCCCACCC
+
&%'#+%"'!%%(*%&&+%'))%%"#)"*()&&+$+&')#(&&)"$#"(')%+')%#!+"!'+&(+'+($!*$'#!))!%%'&)"#'"))!'''"
@r7979
GTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTGTGATANATAATGTTCTGTTAAAATA
+
-!DA/117.8:/&>,B0**G*9-5:(BC&*;,+.9'-+$5%&B'B,44&4D+$%A7>B%"/=B
@r7980
CCGGAGAGCAGGGGCAGCAGGCGCNGCTGGCGTGGTTTAATGAAGGCGATACCCGTGCCTATAAAATCCGCTTCCCGAACGGCNCGGTCGATGTGTTCCGTGGCTGGGTCAGCAGT
+
7D"28#'4:,E1'D'%'<#!3A-(G:3"D9$%$;B?A4-4D7<5=;?.9C2A7F>4E9*<D8$HH3$:9,!</H-/E"(B1-C)E!2.;)-1=$+A$$46$%)"D0;>!.5&)<,B
@r7981
CAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTNCATGGATACAGGTTGTGAACATCCAATG
+
A*>$/AE,;0'!F#'87)C'"4+,7/"(1>F:A%;)/)62=35#2%@:A/;,+;9#C55D#&68E$
@r7982
GTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTNTGATTTCTTTCACGATC
+
-/$B3';<D:H9*=)<6!/9""?7<+=&82"2D-*A:E-+2:23-!B4C8%<:+;:1+9!71
@r7983
TCAAGAGAAATCACATTTCAGCAATACAGGGAAAANCTTGCTCAAGCAGGAGTTTTCCGATGGGTTACAAATATCCATGAACATANAAG
+
5A>2;A(%</.<&8;'0?!,G.".8A!$!.B+!)D),D=?)'A<%$F%67$5,-D&4/'F&AE$5G=0H).,/+*:G++&'-%GB5'DH
@r7984
ATAGTTACGCTGCGGCCTTTTACACATGATCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCNCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGNCTGGA
+
?A77"@"(E097<G=(9*7#*)8B0)H:-?ED3*%F-*9EG1EB-)C9B8?:<&0$6!(%F/79D,;19!'E$A''/B7>$B8B+>)=A;&!+64<7*C.85$87/9%0BF:>7*D-?'<.G<;<G-F))0C=.
@r7985
NNNNTGGCACCGCTTTTACAGTACCCATTATTTTTATGATGTTCTGCTGGATNTGCACTTTTCCGGGCTGACGT
+
!$%!*+")(%*'*!)&$"+)'!"%(%('"*)$!$*"'%(+#%$'"%!""*(!'%*!**#&'"(!+((#$&"%*+
@r7986
CAGCGANGGAATATCACGAATAGTCGGCTCCACGTGGGTTTTCATAAAGTTCTCGGCATCACCAGCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTA
+
<G?>G$GH,C$*"$/+4'EC!?7$(7,019#&6-%A9;A2(;*(8'4>4F<!+?D!(68#904C'>#-%G4><;B<"=G.2'8*1<"('%%C"H-E112#2/98#,(
@r7987
CGCTGNAATCCACGGTCTGCGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTGCAGCCAAAGGCATCC
+
A97B0&&<22!G83*"D+-0;<5?;+H9(3$0/3'#@21847-D?"?>:!)C3#96'G72092-**E"9.5067G4'1D77'H,0*@(90<:F-+;H,
@r7988
TGGCAACCTGAGCCATTGGTAAAACCTTCCATGTNATCCGAGGG
+
2$C@F>!9<!B<%"FD>?G@C"6*%3<D4"":HE?/"F!2'1&&
@r7989
TACCGCACCTGATGCCGGGTGACTCACTGAACCTGCAGAGGGCTCA
+
+1=0+,'D7=+=2;6<DC:0FB.%3*-?#@,/A,3.%D())'G:-F
@r7990
TGCNGGCACCATGCAACAAACTGCCCGGGTGATGGCAGAAATGGTCGATNCTGCCGANGAGCTACGCGCATTNCTGCGT
+
##)&+')*+$&(!!+"*##*!+#*"%(&+&)&$(&)*#!%!&*!#$$"$(#!*"$!*%*'")"%!$*$%+!''&##)#)
@r7991
AAAACGTCACAACGTCTCACATTATATTTACTATCTAGCC
+
$+#($?:/,6938"EEBCA2A4.GG,A9?+G#/%)/G/HH
@r7992
NGNNTNNNNNNNNGGNANCGNNNANNCNGAACNANNTCNNNNNG
+
##!"$!$!$"!!!"#""$#$#"$$###$!"!$!##$##!"##$$
@r7993
GCCAGTGCCGCCTCCCGGCGTCTGGTCACGCAGACCGCCCGGACAGGCTCCATNGGCGTCATGATGGCTCACAGTAATTACGGTGCTGCGCTGTAGAAACAGGGTGTGGAAATCACGCTGATTTACAGCGGCAGCCATAAGGTGGATGGCAACCCCTACAGCCATCTTNCGGATGACGTCCGGGAG
+
'EB!#4&C++,8,)1<A1%2G.H/,3=)05G*:1%F75)+97B7H*2%2,-&'7G7)HB392'+2@0$'6-@'35(%6B!:)C$D81H?;D:(!8?/6)#*H'%5)#%9D%=":94(8$08+->/A&'*;G>.+(/-D,4&HG;'14.A/0=FH?7")?>5'8.#GF6,=@**F2*!G.C?-;"9'
@r7994
ANCTNCANGAAACNTGGGTAGGTNANCGGGNATTTNAGTNANAGCCNNNTNCCGACNC
+
*'('#%"'&)&()%*"(&#&%#%#*""%&))$&#)!&&)&##()*$$#"(#%*%$')(
@r7995
NCCATCGGGGTAAANCCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGA
+
!12D09D0<2;+BBFEC75/)++>8A?/5'D*68=2H)7;?6?+106&%428A&5.@G&00'.@10A(7+<$.D@G?8EB-!D5,)?1.5"&C6B9:AB-/#7-5-B*D(H,=@0!86E@+()E5>/%?7+$-BB)/'GHH(3EE#)(
@r7996
GTTACAATATACTACTAACCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACAGGGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCANCAACGAGGTGTCTTGCTNCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAANATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTACTTCCGTATNCTTCACCCAGGCTGTGCCGNTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCGACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGC
+
(>5FA@-+H7(=#:08E#D3$*+0D<5>&7B?9:<F*,-.B.!/%(&'--4A:>71?9B3$9%3=5*!/4=9A7-,'=/6*;0*527B$)'7A%)C<!"''AA&?GB!#C&G,&GD.-833)!=F:H0"9;&:3!,,.7(>0F7D>F+!0(/2>5:)=//8H*:F,6H1G2*;.8+@(&0,.F7-8!*,1833CD),;6<7,FF@9C-;='B3<FF-"F-9*)B2'G?7?&3"7-6=AH2,$;:A14-29.A-=*G-:;?BH<G2/9!-';2*2EH/H+;A->40-,6?:*%0+*2F)0:=(/7G;?(.<F><"6*D+C%E7(2<$'4-''?:(@))3@H@;'6D$CB.740;,.0!$C&=+3")1;8#F!*,GC6D%G+'A"<<1/,G.=34*D9"(H2+C?)26,45*C102!H$.#863%85C7E<@*E%4"E4%!F&+C9/5ED?)"@&#C&8:639#&6='
@r7997
ACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATNCCAGGACAACTTCTNGTCCGGTAACGTGCTGAGCCCGGNCAAACTCCGCGATAAGTGGACCAA
+
?%B!;-!<55%+&$664/<52#,4@#0E0D';F:7+,B)6:.04%=(4:&+)2=>E79+F9696A=9'=0GA$C=H$<@8H!A'!H!-1#46-67'CBD7
@r7998
CTGGCCGTTACGCCACCAATAATCCTCACGATGAAAGTCCGGCATCTCNATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCGTCA
+
$()+'&(#!$"*$"*(*"(#&#'(%$*%()"''+)&'+)#((*'+#()(&'**""+$$)+%(+'$$!#'*&&+(%&*!*!!()"(&#''+"'(!#)""
@r7999
NGCTNCTGGCCGGCCCTCCGGAACTGTNTCCGGAAAAGCCGCGACGANCTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTTAACG
+
$&*%!))'&$#$'$()+'*$+#&(+'!(#)#'*!+)%+''$')(&)"'*('++#+#$*(")$&+'+)*+'!"("#$!#&'$+)*('&)()+(')(*&!%!#%""&(%"$!&"(**+"$'**&+$"*'&#(
@r8000
AGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCATCCTGAAGCGGCGCAATATGCTCACTGGCTACCTGCATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTGCTTCCGTAT
+
':CEF;#:6$-DDF"=A>6B8"!?!-#C@8<0<&::/0!#689!B2D+925HH>#44G+)D*4G)3A$<=EG:&11CG;DG@=!%<.*!D8F(6)-F!6;?..(316=-F2#,E<5)<?F&5;#9#-1#!*5"?*
@r8001
GCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATNATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCACCGCGTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCT
+
B9D(GC@*5)4D!?)12?0+@&/=.D'8#;?=?#G"@D+"0!,3$>?*F$5"9(<$+=7<#:F!7)1H??.7**$&#20.6<589+*C?!ECHD:E2#=!HF=8"-C1E!*/&,A#)9!G=B5%8H,%!7;D#&B#-6GH2!7*./"21*"5./:"C8*,%6"A;'+5(/97/.4B/
@r8002
CTCTGCNGGAGTGTCCGGGAATAATTAAAACAATGCACACAGGGTTTAGCGCGTACACGTATTGCATTATGCCAACGCCCCGGTGCTGACACGGAAGAAACCGGGCGTTATGATTTAGCGTGGAAAGATTTGTGTNGTGTTCTGAATGCTCTTAGTAATGAATTATCAAAGGTATAGTAATATCTTTTA
+
!1,E'+8&@/=')2;*;0G3EE>2!@&">7@G0&$$866@&9*.>,,;1/B98@.76*BFF#$36?=&D&$8=H=D2#;E1H*,3,*;/8,%&%)=*8&=17.-1,-1$0F-GF=<;,')-"(-;G6,EC7!B(*1#+9"7;8-,HGG&C%1@@>5@'<0HA9*6&7.@26%0&)0A95@,=3*=.DA0
@r8003
AACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGNTTCTTTNATCNCGATTACGACAAAGAAATTCTGGCTAAAGCTCTTNCCCATAAAGCAGATGATTAATCATCGAACTGGTGAGCAAAGATANAAAATATGTTATCTGCCACGCCGATTATCCCTT
+
?0C@B'56$A*1(0.2%A*A4$+24=%E9-=5GBF2'0&,"4@D!!"8BH1BB-(64(G185"*7BAH&4$!-9!+1@((9(0"7&-"C4<:6!)4D1<G;74$F.63D//AG#*>>-3@0>D:;*=H/6G+!79978=0#E26,"B?B3=;9($+<4""
@r8004
GGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCAC
+
>""(C95G0'@>640C07)#?3F1%+F,B<$BF2,'.C):.1!GA"(;6.H,-,D)@;.CD(=6%FHA)/C:,;
@r8005
TTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGATCANATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGTACANGGCATCGGGGCAATCCTTGCGTTTGCANTGG
+
D:)*B'.9H8'8:=/+8*&!#>&4!H65:7%?/65F;0D%8@:D.F5B:)<$473*.9@=+%7%:%5(&@7.#/(:2HF:C,/963,%0*/>(=0GD7C7'H+:608C0:!-"@#E?C.1>D*9D(-;2D>>-3?!"AH8.$GD*8''<EDF7>3&4E;4*.80".2G,.%)?3#>(#++"$E#$."(2"6?5.<#9!D<6,GF/06*%/
@r8006
TACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGCCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCG
+
)2C:EDHG%!)9C,EFBBB4);@@A1:+2E-2F52$+"F1$:#.'63!@=:6>A$$E"6E*3<F*>/7@/48H*;41,#1F$:*0:F#A@D92?9F2?$GGF6<*==)C"(.'(A84F55&?F/:?32615&0H6-55<#@0+5:B!,><9@%"!0E/.B/>H=-+G@4%#(!385)%$CC'.;B+8"30&*6?&>5"<,(@@+HC<'.4HC,F%@GA"G/<.
@r8007
TCCCCTTCGTCTGCCGTGCTGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTTCCCCGTAC
+
+#)8:>#:EE#F3=?<)*$=6.G;:42G?#;'5,+"?1(0;:04C/*74&+A7>-,).B3:352GE
@r8008
CAATCCCNCAATTTGAGGGNTGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGG
+
+3-G45'C<-A"6+1&H0<:"7**+C+F>?D'#90'20>9:.9GA/>5+85B<4AF'1$8D6
@r8009
GAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCGCTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTC
+
;;&*#/$DB;73)<;7<><?$1%CB1$2/D%FC4A7$G):GA<#?A05!*+F4""@&G$1);;.9GHEFAF(@61A0<H4-/>&H9=9#"F.1;5+!C014'#+$(<%!;0!B846.F10"==8AB!/-7"(8?3;@6!
@r8010
TTAANCTANTNNATNCTNTCGTCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCNCGGCTTCATCCT
+
$%'#$('%!%#&('%"#!'*!&+"!('+"%+)"!'$*%)&!('($'+**%*$%&"*"(*#&!'+(!*()*)(#%&*!"**!&'#'!"&*&")&"#&(&")$#)
@r8011
TAATAATAGATGATTCAGTTAAATATGAAGGTAATTTCTT
+
4):(%G%;E!,,*+E=$B?)F'94C&,<$(1'-<D.H/<-
@r8012
ACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCCTGCGCATCNGGATATTAAACGGGCGNGGCGGCAGGTTACCCATCACCACCGAGGCCAGATACTGCGAGGTGGTTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGG
+
>-0:183B780!G@!,0/D"G292"D35&0/";:H66%6*/=@:6(%ED&C)*=$95&FDE!>G+*2@GD55-;=?C?2%:#=;-&!BH4""7#H9%,D@82'5)-@,7E24714/:.-(0):"H6#;+7GF.'"04:0#9B:(@-#8$=(C><7#8=:CB!.656$(.'6)&27H%*9=.?*G<&F>G7B)C.E<")"$="42;1*;$<3F;%>H;/46'6G@+
@r8013
AATGCGCTTACTGATGCGGAATTACGNCGTAAGGCCGCAGATGAGCTTGTCCATNTGACTGGGGGAATTAACCGTGGTGAGGCGATCACT
+
%D.&,:70.3#2583+,C-D@+==?D9<,?EG+5E@4;%E<2F.(465?"95D?<B$H"F>':'$*E)&62.5$D:%1%?10E)0=+?8*
@r8014
GTCATGGTCGATTTCAATTTCTATTGTTGCTTTCCAGTCGTAATCAATGATGTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATCGCCCTCACACTGCAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGACTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTGTTTATAC
+
D(4:"'!#C$AD427E/A4;+??0>)'6)>>(C:?+2)-H3'7*;B7F9$"7H#/'./&F3B-!H$(CE(DC+8#5*!8$=-9%%58,3&0=?&0#9(;:1H,*,G?!6)8$#&>.GH3F!B:,1F97.:DD*=8G'2E*71$)(-H)686$H)3F'@&C70@9FD08'5B>)2;GE<9"D)0#-)?<>!*5-31A#5B?5>;+'CD)G7'4+6*)G,,;."#!9C/2"'G99DG,
@r8015
CTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCC
+
()C>5!(<F4:+95H$0="?&&A+)$=>;>#C40=34,*3E&$&.,H$4
@r8016
NACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGNTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTTGGCGGAGAAACCATAATTGCATCTACTCGTCGC
+
%G,:@<(,#GC8637$3@;.9,-G0?%4(#A<<!3H2=G2$6"=<)F@/54>"B.;FH:55:-",)-%C+63%E4=.F433/.3@"@$>(52*5#=H0*!%.<'&5;!.9.!+28EC869B>CB<3+84H(-CA!"9>$A<'!@*2!.(,938%EA89:4@8()@;F*&!314?"*3(-"=14E7<A6>0".E)$%>#6,802?1//'5.<>:43:;6:#:>A3HFD=>12H<HC+6FG8!6<+;C1*5-B$5>"+4/7AG(;"AD?;>(>(9@*F+@;"@@?6.'=(#1#>1A9;7$664<,$>.@C.0,BE?"-0@A!*F#
@r8017
NGCTGACCATCGGTGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCATC
+
!@7,.$E5@4;7?B<0;67>F@+1$&E:37D0>.()3%#<GH$13-@&/'?#*0533!:(HD%",/8=)
@r8018
TNGNANCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGA
+
"#$%(*+&##&&#))+)&'&(**(""#%'!+*+#+*!!&+"#('&)"'*+$%"&!+*'$#%)(+!)''%+**&)
@r8019
TNTTCTNTNATTCGCATTCACCCTCAAGCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCNTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGANCTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAG
+
"$&*$(")"+!&'(((*!((''*("!$!&*%)*&&'$*)*&&!+&)!&"&!!)&)&$%+*%%$("!"+**(%&&"%'(%"%!('$%*+(+&#*&!!!*+"#*!('$+&"'&&'(!)#'#$%"%#&!%(#(+'*$*#*%)#(%#*%'#&%!(+*!"++#"#!+*+'&)(&!&'(*'%%)+#&#*'!%!#+')(!*!(%"%)+**#!$"+)+()*"+*+*+"*"+$%)($*%)(*&""+###%*#+%(&++'+''$"*(()("+"+)+%('()$&&!)$#%'!)$+*%*+#'()!+(&*(&+'#)((&'"+&(&&$(#*!%*%
@r8020
ATGGTTTTTATGCGACTTACCGCAGCAAAAATAAAGGGAAAGATAAGCGCTCAATAAACCTGTCTG
+
+"*#"$&"+)!'#("+"''(()'&'*'!&$%'')$(()*$"+%%)&(("#"*++&#($(!#&%(*'
@r8021
TGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGANACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCT
+
@/@&##$@!9CD/?7@(?1+(-D-9)"G(;E1&77E/@,G=!*&*?"75G:9,&-?=?H3;2E89(8:%D"1,1H1
@r8022
TGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTG
+
A:<#'=D&C,84(C:&38D,F+B:!H;A5G:#51;;C)F#1&2,!;*$"GC-*H7#G5/@A,6
@r8023
NGGGCAGTCCGGCGGTAACGGATGCTTCTTCCCGGCACCNTGCAACAAACNGCCCGGGTGATGGCANAAATGGTCGATTCTGCCGACGGGCTANGCGCATTCCTGCGTTAACCTGTTCCATCGTGGTGATCCCGTTTT
+
%"9)C,;;:0""E8G+-<G.,-:9;F#$0;?&H:#''"$+)&?F(/%@D:-'/85(G6=,'**4BB;>)8G3<A&%A!23C4/E8B'5;>C4<7.6$==&8!C805"C*3;,.+H)GEF*-*./.#D0=;G-F9ACE%
@r8024
CCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGG
+
!<$,E,90FG='/0-3H=H*&69B:H;EH67<%!:<8-.(&$79-
@r8025
ACCAATTCAATGNANAAGNCCGCGAGAAATCCCCAGTCGTCATGCATTGCCTGCTCNGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGANCCTCTCTGTTTACTGATAAGTTCCAGATCC
+
'&(((((%&!$*!(!%"(!*##&!"+'('&*(&++"$))(#'(!(*'+!!&%'(*)))*#!'#(!'((#&"'")""&(+%!&#%$$&*(&)$)""*#%+!#)'(%')%"(*+$"'%$)(#&(*'%%"#"'*
@r8026
CNCANCGATCAAGCCATGAATGTAACGTNACGGAATTATCACTGTTGATNCTCGCTGTC
+
%"!&&$+('#&&)!&)#&'*#%'&!''$(!($)&#)#(#('**%'%+%"))*!'#&'*)
@r8027
TTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTANTTTNCCTCTGGCGGTGATAATGGTTGCATGTAC
+
F;D?;0<=/F/2!BF5$:7&1&D1*B=>D-/4>=%4-=5:'!D)=5(E4&#>H.7C$FB9*0@;A2"%(B%,8,FB0-E3)2&7@AF'("=2C7$BA==$)BF=A>
@r8028
ACCATGCAGGAGATTAACACTCTGCTGATCGCCCTGGATAAAACATGGGATGACGACT
+
11#4.F:68&A)91D<B*=!"D51;(H4/E<"B1:D*3737A30:GF@$4%5++;+04
@r8029
ATCATCNTNTAGGANGCNACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCA
+
#&$''("*"$$&!*!+'$*'%*(*(((#&'*#+$"'!+*)"(!(#&!*%&"$+&#
@r8030
NAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCNATGTGCCAATCGCGGGGGGTT
+
&)$+#)&!))%(&$%+'!!($#*#'*##*""*+&'*')'"((&*()!$!$##"'#&""(
@r8031
ANGGTGCTCGGTGGTGTGGCGCAGATGCTGGCACCGAAAGCCAGAACTCCCCGTATACAGACAACGGATCACGGTAAGCAGAACANCTATTGCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGT
+
)(+&&&&!(&"%+#&#%&)#!+$!'&%"%!"#+(&*#&'*!()"%!"%!&$#*)"&!"!'"&()+&$((%&#%&)$#)#!)+&"(*'+'(&#!'(##%($%+*$##&")&&$$*!)#)#*(#++*&*%&+*"+$#+#
@r8032
TCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATC
+
B?-0C/C:<7=A964H@?,%H&17C@21E6*%6-;;$#,@4@8B*=DC>5&<
@r8033
GCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGNNGTGGAGGCAGACGTGGCG
+
/1A(,)C/E="A/?B%!)+)(%<E.-4G;,E9D6@#H<,E!&%%,'.F%$>96<.D(>1+-$,$4G3D7:5"D09@-&,&%<'&+H(4F<G)0*F("6:871:+C(&H#""8)!H*9:?5G5<=DA;%#@,@@#C0&-20$C62;0/0;'?*=,>#9+30FC(8EF2.*H2<$73,+1G.>DB/7H3%")7=*>.6&&<$.!H8DD;6:7
@r8034
NNGAAACTGCGTGTTGAGCTTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCGTANTGCNAAACTGGAAAGCAACGAAGTCCGTGAAGACG
+
%"2DFE&'48$6%8:5=%A(8AC'$(%2>H-"'9<"%'#F,3>*(16!B;6#:3=+&7#.,-@2-#'F:=#>!'>49<49>&3&-E>,*-'.F;;<3*4!GC4E'A*;*.G;F!B!8C5=?5."-*"3>,
@r8035
CGATTTCGTCTACCGCTTCCTGCCCGATGCNGCTAATCAGTTCGACGCGATACGGAACGAGATTTCCGCTTTNGTGCTGGTTGCACACCACGCATTGCTTGTGAATANTGCGTTC
+
6)&6*>D,@$H6A'(AD$&)8*&!77.#&.;@(6E85,!H$0A13..1BE)GB@2>/5;"6'45A:B)+7:A-@-02&&!F'1G/5*(%;4C*&11B0:D!/0,1:1*$!=)#78
@r8036
NCNACGCATCATCCCCCTGTTCGTCAGNTCTCACATCGATCCCGG
+
%*"0!C;3<86>,/0.9*$&1B-:235GC0).7#96#?458!.4!
@r8037
TGCTTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGAT
+
*-==;:#@H!H=$)$16::$#7"8$D7>G?"47*'H27"B;2"!H2F45BD:-*)"!&#7:
@r8038
CACTGACTGACNGACTGCTTTGANGTGCAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCT
+
6F-C4<-"14(3G<'$&B0$,6@D>3G-1C752'4*;GH80$D/G&%F1D/F29:>3;7C?C!AF<1B#5,)0@&)G+-97GE-??@@!=$
@r8039
GGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCNGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTC
+
*2:->G4H@?F.F?+'C1.(049+=D-B0&"<1!67>";A9A/-,.-@/>(%08(A;D1/?=E.B@5&A.A8-!)0E/<C7+3!G,>/&53?4!>;.'(+<*<A4#G%81*2?9!5H'B'9>;)2AA*!7-/)!=7!414;)F>%:5.?:5)72+=>7=-4?A")&2==#C;/'C-B)5E:GHC;-$E!7G8)
@r8040
NCTTGCAGTACTACTNGGGAATGAGTTGCAATTATTGCTACACCATTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGAGAGCAAAGGTGGATGCAGATGAACCTCTGGTTCATCGAATAAAANTAANGACTTTTCGCCAACGACATCTACTANTCTTGTGATAGTAAATAAAACAA
+
!GGBEG<@.9*&G!D,#=;!CA8;/@8)DD>+5=@A*=(;9=0$8<G36&G5.5EG7$81:61.;&D(A50'$#08"/G2/C=3-%+4;4%G+3A3-532$"E-?@27D49$B1;0<H;34#))9G9E9E10CD5'H?@@.,F:83D?,@1*3(#*-"%572@C9/-8G6H9E?+G/,2F!1+CA.-
@r8041
AGATAGACTTTCTCCGTGGTGANGGGATAGCTCTCACGGAAAAAGAGACG
+
D:%D9**GD+13?/9/@1<,#<"G?&*A2?=83A0=35G$4,%.,/AC%)
@r8042
ACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCANAAAAGAAATTACCTTCATATT
+
6.A8$:$BH-3"B4!!E6CG':"5056;C:3,D3EH7$>F92-0.$4<+E<A(A.A%<<,*3:G0'B(D;-%*
@r8043
TCGTTCNTNTTGGNCACTCNCCNTNNTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGC
+
#&!!*!!*!&)*'"$)%')!')!!&$+(#%$$%*%*#!+'()$%!&&)$"&$%&%*&$#))%('%'()+'(&'*"%&$$)+*%"#$"!)(*$%!+'"")'"
@r8044
NAAAAAAANTAAGGCNTTCCGACTAGCAGATGGTTGGAATGACCATTCCTTTGTTNCAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGATATCGGAAATGTTAAAATTGGTTTTGTAGGTCATAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAAAAAT
+
#$")(&&&%''*)*("&)*(!*$%+&!$%%!((!'"(!)%)!#"($()+!(!()'$$**()+$)'!+"#)"'+!&+'#*%)#))&&)%!'$)((++$"$'+#!*!&+')')#!!$'+$(&!)+&$"&"&(*(+#)(+%$)&&$&$$)+%#+(!''"'*++"+%%(#+%#((&!(##
@r8045
TATGAAATAACGTTCTGCGGTTAGTAGTATATTGTAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAAGTTCTATGACTCAAATGTTCATAGTGTTTACATCACNGCCAATTGCTTTTAAGACTGAACGCTTGAAATATAGTTTTTCGTCATGTTTTGAGTCTGCTGTTGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCATCTATAATTGGCATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATAACCAAATGAAGCCATAGGCATTTNTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGCTTGATCTTCAAATGTTGTATTGATTAAATCAATTGGATGGAATTGTTTATCATAAAAAATTAATGTTTGAATGTGATAACCGTC
+
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
@r8046
TCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATNATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGG
+
@>8<#C?<2/(C>:H8*7+<D&E5(&@?CCH7?*3;C9?1*C#)675<+@-HEC@65-H>4,-7>*&*0=9$;<*<G8E&@$@&H49DB*><(>A0G**/389E1+/7>/BF"4.%%<=&3?)2*5GD&+
@r8047
AGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAG
+
>+&'(*=;6C1-'-%C6,4%-E>12(><G$2.:<F7/%(@C@("*'
@r8048
CTGGGCTTTGTAGGTAATGGCGTTATCACGGGAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGAT
+
8.B-$9;6;1).;32>&==$H8(=?.H&041C-<;"B%.3.;-A7>2%8'>7<>6.33/6"=A=!C$BG?91
@r8049
GGTGACTCTGCTCATACATCAATCTCTCTGAACGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGTAAAGCGCCACGCTCCTTAATCTGCTGCAATGCCACAGCGTCCTGACTTTTCGGAGAGAAGTCTTTCAGGCCAAGCTGCTTGCGGTAGGCATCCCACAACGACAACGGGAAAGAAGCTGGTAGCGTCCGGCGCCTGTTGATTTNAGTTTTGGGT
+
AD?4/8B/G=)+6$B!<1H!><2#9!H2A+,)G1.742E@F.A-A0)>3>=B9-2!"=F,B"D'.+.*254(/<7"93(?*#1D+3+>?:)GC0&)<?5+,%F@49)/0B2#9"!4C",9H7)$F>'$%.5)B"?=;&/A7!>G$!"GB*6E<)-&6"5E375!$;B>#9/.6A>B:=5H9D018B;0"3H+?3C0=F'@>)><#6>5*2!/&$<)H?$,6/$4<B2A.<-(?2DC*=H9'/@)=11-:F+=?ED!E7!-:=5@8C6-!A#E"-$8C!;50'D35D+CBD%>3+3;4!/B#/=,>3/909D!H617C-&+$G)%546
@r8050
TCCNGAGCAGCCGGACCTATCTGCCCGTTCGTGCCGTCGTTGTNAATCACGACATGGTTATTCTGCTCAAACGT
+
(%(!%*%+!#%$*)*%+*)%(!#*(%&"!&&&()!#)%'%%&'$#$&!%&$#'(%'(%"&+*)('*%!!*'!%$
@r8051
CGGTNTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACG
+
G?C?5!9D,<9??+-8D?(394;F3#G.DG%1#":/9H,*B9?D-5B>9>'/;=C36@H'<C0F7!<E(:!@D
@r8052
AAATGCGATATCGGAAATGTTNAAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATT
+
:H3BD9=;+D3-?F46G='%"!B5+<+G@F!E@:F4@0<A156*'??H-&6E@1AEF6?4"H*D
@r8053
AGTANGCACTTATTCATNAATAGATAAAAAATTCAGTCAA
+
5>))G;%#;#5=1="C=H(8GB=-&.'3HF(:BD&%!FF,
@r8054
TCACAAGGGCCGGCGACCTGAGCAGCTGATGCACTGGCATCGCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGTGCCACCACGGACGCGT
+
9A)%$HD"?"F@,,(%9,")E*E&,9$&+;";C60C64=::G/3-&BF1A.1GB*5/<2;(2=C7&1BCB:-B#'/H1C&%>$6)C<A'0>
@r8055
TTAGATGGTATTAGTGACCTGTAACAGAGCATTAGNGCAAGG
+
@02'F7?DF4<'/A(B?E%9.E-D@H*54<2.-22?G/8?1D
@r8056
NCCCTTGNNATGATCTATGGCAGNATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAATCCAATGGGTGA
+
(%#"*!$#(*(!'(+"*%*'(#('&+%"$&#%(!%)(+#!&'#'"!&'"+)(#$"*+)*#%(''('))!$!*(#&"(
@r8057
CAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAA
+
263G;<!:857?(68#G>'>&)G1?(#.BE<%'*882*!=:8?DDF#,
@r8058
NCCTCGTGGCGTTGCAAATTATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCC
+
!('!+))!&%'!%"**"%!)&*#)#)*%'(#!)'"$#))''!!*'#!+"*(!&!'(#$%
@r8059
ACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGC
+
F31$2#>@;<13D*"?,??E=F$AGD443%2C6+6?8+7;C>.@!?
@r8060
AACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGC
+
E.@D@2B!%A<'#+'F-A4'&,38E.1H4.=B+812!5;-<#@-4&)E5;<*D!*)9620*G'.;E
@r8061
TTACCGCAGCATTAAAGCAGCAGGATGTTGTTCNTAACCTTGCCGGGAATGG
+
@5)#-;<=GC.+23BG+@D6@01/>61?E*&!)DB@<36F)2.#F58F>?,:
@r8062
ATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGNGCCGTACCAAGATAA
+
$+&+FD:+'E%/,C2B97>@4G#!"8AF-#1A7#*"8?%"4@#5!8!,A<C*HD21>/
@r8063
CAAAATTATTATCACGAGTACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCNAATATTACATAACAATCCTCGCACTC
+
0!0B,'8FC?F/(10AB3!?;<(!-@A@-4"H,*>>%,"G&E5%6'F+F3E!;+;6G7;>,:#E71)"(F;74<1(7.>6<&4%@+,(3;FC;,B2-:;
@r8064
AACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGA
+
B92?+)3$0A;'D51@)#-"&:;()H,=*H,FA@$"C:'/3#B
@r8065
TCAGGAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGATAAAAGTGCCGCAGCCGCAGAGTCCTNAAAAAACGCGGCGGCCA
+
*%%+'%(("*")+%$))"%#)#%$#!$!($#!#(#+#%+*'+&"$(")"#!'$"$++*'!"!*#$+!'"!&+'+(%"$)#*$%)'+&"&*$&#('&((
@r8066
CCATGTGCGTGACGGACATCGGGAAACGCCAAAGGAGATTATGTACCGAGGAAGAATGTCGCTGGACGGTATCGCGAAAATGTA
+
A:42+=G7&":,.H1=8'3E?.G&E,,..9><,.@,$4*/6(7#6A@(75G%?G"73D>DF>8F!B/"+)0$6BG1?G%'&EE"
@r8067
GCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTC
+
DE&!@.B/-8-?$-+B7+/G':C49298G":F?6&$/E+9-0:8@$
@r8068
CAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGAT
+
;1A"/G'/G5:>7E%<173'$EF'"07;%G6EB('9EBF,D98?)G7(%C'*-!A1)*H7.,/F
@r8069
CGTAGTATGTTCTAGCGGGTTTGTTTTTATCTCGGAGATTATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGT
+
D%,=C<F=4;*;!)6F=H:FE)'D6*(%&'1C@DE71!416+B"9A!&,5/)?A;<B7<=7?H!=31),A:249#F1HHH:!ADH:>,;8&F@;?/"'@?$G9%0++36F:$G
@r8070
TACTTGCCAGTGCCGCCTCCCGGCGTNNGGTCACGCAGACCGCNCGGACAGGC
+
(%+&%$+$%+%*))'*%"!#''&*%((%%()&('*+)'#(!%!"*&$*")'#$
@r8071
TCANNANNGGTGTGNTCAGNCAGANACNGGCAACTTTCCCGGCGAGCCTGGCTA
+
'%'%%&%#()'*$*$(**)"'#%!$)*!+$$&$%%&'+('#'''++&%)&"$)&
@r8072
CGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGNAGGTCG
+
G8</&!:@-@8<?EB>)6-3-.#*(5*%4D%-=*2E62B-'>>.@0-H>!27%+)5BGH#7C1*$,)<78H6+8>6!1:?<;0F;FH3,1"2;!?3##*17D
@r8073
NATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCGGATCTGCACAA
+
#:A#30"H?'<=0)(8.F+#90H&%"CG6,9<5HF'#!F(?>/37";E>A.E#8##@%)4A==6*3*?:4FA;#!G=4FH83-&9F46EE)
@r8074
GGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTAC
+
/1A296+;-HH50:GE+#B$&"::;B(A(8*.%+;<+:<33)#-@2/=6FC,8C>%=@992FG5!C2$(=#6/<D=?A>5;:+(C7:
@r8075
NNNGCCGGAGATATTTTAACAGAACATTATCTATCAGAAAAAGGCCATCTCTCAGCGCCTCTNAACAAGGTCACCAATACGGAGATAGCTGAAGAGATGTCANATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTTGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAATCATGCCTGGTGTTTAC
+
(##,>*=-:%@3+>"AD5%-4:H0-;>0')-<<2>'25)?)B=%<5).1(E81<"0@6.875/DG!>$1?65<=G@3C6+76<H%8F?5/?!%2>=?*CHG:,.?;5G0#;4A>(1DA+B<D:E;F-21,2&??<+!57#*!#9;,!)*D"AGG?E?9"DF&/%)!7%;7:/8+!$D6E;2,1$&!DH0AG2HC4?@E'>8(>5/"%$A>@5.92.*#>
@r8076
TATCTCCGGCAGATTTCNGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCA
+
8(D$/:6F/9/8=F'G<C'0;E,&CD+?F;@H05B@.0-;0<<1D/$2(+&A1
@r8077
GCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCTATT
+
8)==#927-9+C*)7()G#49B?=>6BC).;G+'B;-%8,'0(=>)2C!#850?'1,),30C16F)1<1=72@$05)D+4/0/$D9#7)=523?$6(H))"A?5B.4A06;)4#FB>7>$6;1'):?)-D*?>&<!+G479?!5D9<5A
@r8078
CNCGGTACCGGACGGTGCGAACGAGTCGTGGGCGTACTTTATGGGGC
+
(!&**&))"$(%'!$)(*'+#)*(#)!%'')$%"*(*$#!&)*))'!
@r8079
NNTNCNTAAATCGGNAAGCNTNCCGCGAAAGAGCAGATTTATAACCGCNTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACATCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCNAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACG
+
("%')"!%'*'*$($$&&!"#!)*+"'&+(+*+%)!#%%"*+(*%&)#**)#+'*%$&##%"***"($'")&"!#($+#$$%+$'&*)+*%(*(&***%+"("#%%&+''!")#&+!$%'()!$($"*"#'"&+(&!)+'##!*((%#+)&#))+'&#!+*%!&!)#&#)'"("&$&'$%%*"!(!%&+")(!!*(&#)"+$*"!!!#"#!$"+
@r8080
GGAGGGANCTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAGCTAT
+
,76+F/-F*$'9)?*9353B4)$+D<:A$"19,A*'G;&//2D#56'4A$0%B'=B@2D8.6:>D@E717H
@r8081
GCTAAAGCACTGGCCTGGGGAAAACAGTACGAGAACGACGCCAGAACCCTGTTTGAATTCACN
+
1/!F6-029@=4+8#4=.!$(07,!:"9=8@7/*DF6GD35=>.HH'4GEH24(1.=<)/>E@
@r8082
NCNGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTT
+
%(!+)$#(+(*+"*$'%+&&"##&$!')$#''"'")!*"$'!!!#")!)!)#)+*&!$+%$%"$#""&*!!*$'(+
@r8083
TGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGANGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGNGGGATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACNTA
+
*$*+)#('('#'(+*#'$#($*%)*'!&+*'$#'#)!+%)!+*'$!'"!')!+!$)"'&'$&))#)%)$)*)"'##*)*&+!)#!%(&('"*'%')!()$&%#()%()*()%$%""&+'*)"(!#&!)($'&''!))#"#')#+(&$*'#+&$")!#&#$+*'#)"&
@r8084
TTTACCCATTCCTCACGCTCCATAAATGACAAAACCGCCCGCAGGCGGTTTCACATANAACATTTTGCATCAGCGACCAATCACCACAACCTGACCACCGTCCCCTTCGTCTGC
+
,*ADC(*8>!%,<+:A4.3'3?B../&!3+5+4=/$?0??*0/,AA;<&+8B0&H>1#4*=(6""&!*="(0E("%).2H80@=>035;&551.5>D><C599!A#->;E/,-/
@r8085
TGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTAGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACG
+
@@=G=66/B7D"-%'26<7<:D"7-7%'E+7ED?+!6:35A1(15D%FE<E<'!6;"3$%*!:&63=D48*6,18#,9:.->3*%"1!!(+#E6??20G#;)B>1*3%AF.&6$&849HDA67H$*)1""$$6D+GF=B;+59,0
@r8086
TCGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCTCCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCT
+
'A/%D*$+)2A3'+*7E'8H?"&FC6H?6*-E#01H.6GH:8$025>1)+-5%!1<=:CD8?660D8&.!D5<9C,58(!G(1*)96-F=!3F?A+&.-A!#!&=20B#3!?C(@;1;,(0+"+F:&$26>C(:
@r8087
TTTACTGATAAGTTCCAGATCCTCNTGGCAACTTGCACAAGTCCGACAACCCTGAACGACCAGGCGTCTTCGTTC
+
@,(>+G;<&DHH'10'HG$0G728,9%";@&&?DB)!C=>,-1E43?52/03'=7B<3."#534F%C;B3*=47,
@r8088
GCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAG
+
'3!D112-9-,<D(=45(A9)&,,:7H0&7F9"'=+9)'*.=*'$>
@r8089
AAACAGNAGCGGAACGGAGCGCCTCTGCCGCGGCAGACGCAAAAACAGCGGCGGCGGGTAGTGCGTCAACGGCATCCACGAAG
+
<<8"!9H64+(7C(2,G9F&6B2AH><4-,:8,C":-'0A7G7D#<@,/-!E+(7!9%2H9=H>C+>!<B'10*1?;G=->)/
@r8090
TTCACCCATTGGATTGTTAATTTNTATGCCAAGAGAGTTACAGCAGTTATACATTCTGCCATAGATTATAGCTAAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCATCGTCTTTC
+
(?/G@(5-F&F:C(<1*"6D6C7(3324D'628%5E2++D8..$"3-#,D<C"71%$!'9&)::'#<2(*)&3,E'93724-9-EH7!4"$,H2=0-5>272E00?,@:GH8E,7,)?9*&,:0+>
@r8091
TCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGANCGAATACTTTTTATATGAGGAGGGCTGTTNTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATG
+
($=H=BA7!B++FE*1F:#F"A@-'3@F3/5F>();GA0!&>4BG$,=1!=3E09'"DAG54<)B10++265BE,9(<%#@D$)-/?EF(<*8@!C3)6/G&$(0)*-"H5A,B>4'AF#?;:%)3-#>A69E:B$H!=.-4
@r8092
GCAACACAGCAATANAAATGCGCCGCNTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTT
+
G$/+'50@.B:G?D-?1-80)%8+;E:>&$<)G3D*6AF7?9.E<A)&)/E48B>!77'=?>D%13!93E"(#':"1%.;5>+9+&+=4@F;,8#<+.00.09&
@r8093
TNTGGACTGGCCGTCAGGTACCCGNACTGTCANCGTGACCGANGACC
+
'#(+")')")!%%$")##**(+$#!#'#"!&**(&$(*%!%$*"+&'
@r8094
CAAGGACTCCTTCGGCGGGATGATCCCCATGTTCAGGGGGCTT
+
!H=7B5B?5;D7A!-#:%$A563+4BA,#=3F-4".-3F&:?B
@r8095
GATTTATGTTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGCAC
+
(DD)$4E.5?HD"*>+,-$7=(&;D>"4?%";A!,#5$CF*;)6;&<$=?>
@r8096
CGTTAACAAAATAATCTTCCTTGTGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCA
+
F<.=1<2$H7$"=A7:&D?CFG3((H+&5""$'+'"#$<8')#GD:3<E4)C%9"1F4)@F9D;"@@?)$C6%)6(C'
@r8097
CCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGTTATCGGTGCTCATGCCCATTCTTTCAGTATTGGTTCACACGGACACACCATCACNGTTAACGCTGCGGGTAACGCGGAAAACACCGTCAAAAACATTGCATTTAACTATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTNGCCGGAACTAATGAATTTATTGGTGAAGGTGACGCATATATTCCGCCTCATACCGGTCTGCCTGCNAACAGTACCGATATTGCACCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCANCAGTGATGAGGCATCGTGGCATCTCGTTGAAGACCATCGGGGTAAAACCGTCTATGACGTGGCTTCCGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCNGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGA
+
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
@r8098
NGGANGNNCGTGAAGTGNTGTCAGTTNGGAATCNGNANGATTCAGCGCCCGTTCCTGACCGTGTGGCTTACCGGCCGGTATCG
+
$*%"!%%&&%&%$%)"(!(%"&*'#!!($$%#$'(!&#")+*#!&((!%#$$("(!"+*(!!*$""#)'((+"*%)(*(((!&
@r8099
ATGAGAACGTCGTTGACGATGGCGTGCATTTTCCCGTCTTTATCATCAACGTATTTTCTGACCGTACCGCGACTACATTTCAGACTGCGTGCTACTTCTGTCTGATTTCCGTATGCTTCAACGAGCATGTCTGGAATGGTTTTTACTGAGAANGTC
+
#(D%A,<%D--F.H;0F9HA*/CC7)?4>/&EG@%(<>(,1/@@0.0D))#&1)C2!C.,@97CG69!EC@="?E(,AC.1'H&@05E&'(!0#(-3F$$(>)6%1>+BB8#:&#ABC'E),)3%',6;BC%C*BA;"G'G<!8707;)5'<(9.2
@r8100
AGNANNCCTGGCATGCCCAGCGTAACANCACACACATGTCGCGGTGGTTACGTCCGTCACGTTCACGCANCAGGCGGNTATCGTTAGCCNACCCAGCAAAATTCGGTTTTCTNGCTGATGGTGCGATAGTCTTCACCATG
+
&)*!#"((+%*!#*('!$!!!!))#"!#)&#'*"#'#&*"(+')+%!**&"*+'*"+&"*#(&%&##'(*+&!*)&!*&#*#()(#!#+)%&)""#(*(%'"*(%#"$"""##&"!'*#*(+&*&!#!%)%'(*'*#))!
@r8101
GGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGGTTTCTGTTTTAA
+
'C1"'>-B6@C.21?H+7F21G+9"4B>):(<+0.'@10:B7@<&*/==*13$;*G/H?%B19<9*=>>B<
@r8102
TCCGTTACGTTACATTCATGGCTTGATCGCTTCGAAAAAA
+
+)""!&#'!(%#%)%%%"*(&))(#%&#'#(&+!%")+##
@r8103
TCTCCGGTGTGAAAGAACACCAACAGGGGTGTTACCACTACCGCAGGAAAAGGAGGACGTGTGGCGAGACAGCGACGAAGTATCACCGGCATAATCTGCGAAAACTGCAAATACC
+
28<F9!'#66!)(D"+"7H3*!;)A,D<84=HF-(6-D?<.959(,E7-A26D9F+:HC#92=$D)3#40E22!A0.=C#)&;0:)D'>.%@2.#H=0.$BC:D&B20&HCD6'>
@r8104
GCGGGCTGGCTGTCTCGTATGAGCAGCTTTCCCGGAATTACGCCCAGATGAGCTACTCCACAGCACGGGCCAGTGCGAACGAGTCGTGGGCGTACTTTAT
+
$%*)+#!!('&'*)+$("!()%!%#)"*'('''"($++"#!+#+++!#"#%&%&$$)+%!$*")"+!+!""(*))#!!')##&**!")!'(")+)')''%
@r8105
GNTACTATATGTTGGAGTTTAGTGTTATTAAAAGAGGCGGGTATATTCCTGCAGTAGAAAAAAATAAGGCATTCCTACGAGCA
+
'"?F1>0F-;#6";GB"%6.>-9#6E0"D:*"4539E=;*63EFA8A8<E2)'>//60F")0*#C#5CC?%1;3C.>+&:;)F
@r8106
GCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAATCGAACAAGACCCGTTAGTAACTATCGA
+
<'660&3@C#*.9/H8G4/:=4>-&&@=,6(%30H>/=+"498&9>-/?;/"##$B1*D(&>+/
@r8107
ATTATCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACCGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGATTTCGAC
+
*4=('H6F%56>@=4@(2&+&A?.;@EGH60;#=8-H#28+-8A)!(H3/51!=#H@?994E(H$=''G2*D?/8HF=?@?)493;A9<<E>9/<4<>)$0
@r8108
GTTANCAAGTTACTACCGGATTTTGTAAAAGCAGCCCTNCTCATATAA
+
E':G$%.6=*HH?+'579?D%)7!C@E&#5+"<8G:0>D2G??!(D;F
@r8109
ATGNNNTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTT
+
!%(&($+"+%**)+%$((&%+$+(%&*)**"*"&")&+'''''$)&"&%+)&**
@r8110
TTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATAAAAACATTAAGTTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAACTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCACCGCA
+
F#,*BG2!C?,##<7),AH2*B5!:@:(-BB8H940+!>&9%C0$AC(&/.B"A'9/"7,A:,H649"F,&%6B*$HC,2H4H6A1?DC):$"">%?BH$,>6=@B!'67C,GD0B9E663E&>,<7):8#$"016/*;;A:./!B@&.70#<(4:?H9E*B?855';8:B/#1G<8<E44AGH-C13*$'$>+
@r8111
AATTCACTATCGNNACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATANTGAAACTGAGATCAAGCAAAAGCATTCACTAACCNCCTTTCCTGTTTTCCTAATCAGNCCGGCATTTCGCGGGCGATATTTTCACAGCTATTTCAGGAGTTCAGCCATGAACGCTTATTACATTCAGGATCGTCT
+
2EH!ED9'3.G5E?4##>G!"+/E96.E-&+'5F76&A.8&#9(8H3.D@&58,=58&;51;?&6!-%/=19C;!%C1?(=E:6>%:.?+@<>/@58+<G-@?-HE6,&61!'HC5/)H"(0-;/(<7@,0#';7(1>FC*<B'B*7D&;&$5A&=:@!)$$(&(9E@9."296'AHD0&%@&/7!'</64?)-=%+1H:%B!)'+6?C,'E@H52
@r8112
NCCTCTGCATGATNATGCGACGGCGGCGGTAAGCCGGGTCCGCGAGATTCTGCGGATCNTCATCCGGCAGGC
+
!('*+)(#(%$((#)&'$!%'##&")#)+&%'')*++"('#%(#'%$+'#')&+#$%*(!'!*"&#('()%&
@r8113
TGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAAATGTCATATCCTATCATCTGGT
+
A6<7C*504C4<;'E%;*<3#C-!$@E:,<(CE@,?6GA3?8@')=H3:A)8@/'$#.*,)85>%
@r8114
GGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACNCATACTTTCGTCGCGATAGATGATCGGGGATTCAGTAACANTCACGCCGNAA
+
=%$%@.5;@G3/<2:,-9%)!<=$.G6E8:/+;9HFG@&.<4"<;@B:<C%H32E0H5+&74&+!&8%A46AC5E.$80+>=(*A,40$6!2.1&1GE#0-33/10;(-,96@
@r8115
CGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCGACGGCGGTCTGTGGCNCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGT
+
G%"4&2&%D$?@08;4A)$?+/"(.<&).&$<EB%-:-%?2%E.0"&A"!?6<",D)0;-'/3=BA</58F-&2'F%735?)F'4/:"5+B%E$H6&HG*4C%&:."(C..'D;,!)AAH@*GE9"@/0<+G*A:8.%4HH"?C1<;18"/"'+?;B6;4<09;F1.+(
@r8116
NATGNGCAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCNTTTCTTTTCAGAGGGAATTTTAAATAAAAACATTAAGTTATGAC
+
$%!#!$+&*"!"$%%#%+)$)#(#))*))$$%$"$&+"'*+++&#'+&##)!#&#"%!#+"'"#!'+*"(&#+"$'!"(!&&#!#'#))%(!#+)'%+$+'"&"!!#'(#'*
@r8117
TCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTCTCGCCCCT
+
5EG!8/94.*-HC,>*'D&5"&-0/E>8<)@7F*B4%%&,:(<F$B
@r8118
GTGTGGACAATTCAAGCGATGCAATGGATGCAAGCTGCAATCGGAATGCATGGTTAAGCCTAAAGAAATGTTTACTGTAANGGAAGATGGGAANTATGTCGATAAAT
+
5C5;'%7B.22,F51G-'+<"@>?)5F#8?)F4;$(%HE#9>;*?A7>C"#+<F=5E<5.:G"?('6?1E>;4;5E+.CGDC5+",+?B?%:H9"5<%7F->H?4.3
@r8119
TCCCCACACCCAGCATGCGTACCTTTCCGCCATAACTGTAGTGAATGTCTGT
+
9;D963<"EG?3!078%8:=9H:0)A/H82C18*">'0=/64D!?D$=HC2G
@r8120
GTTCACGTCCGGCTGCGCCGCGCTGGCGTTCTCGCCCTCCGTCGCTGGGCGGCGACCTCGCGGGTTTTCGCTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGACAGCGAGGCTTTTTGGCC
+
%6D0<-4,#/E>B5<.>,=CF99346F#CF)HA%@6#AF!H2F?#C.23B9'AA;.?*6:+=-?;*!/-F&(-&0)96*;>G*C&,1-(:!0?=#D8=!!+:#A=1D61'FC.A,+$.';B?%92/33>(/G>;4/$/(B=<;2-#,G01E>12&00."-$D):*H)#!74.>=2:?1F"FD&1!,D@8CG?BH5
@r8121
AGACGATCTGGTACGCAATAACGGCTATGCCGCCAACNCC
+
.%D<89%:3.C=4H-"'0:H/&H13:'21#G,(0)9>F(;
@r8122
GCANGTTGTGATATGTAGATGATAATCATTATCACTTTACGGGTCCTTTACGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGC
+
@"=/0+1+5&'7+$9#;16"G6E?)4%,-1<)A<H'398&H4:?&<HH,*)1+*6=<+003H0C#$+5G!55"H?='"*98+#A4='H'G"3B&9(B)%:8-%D$1B<'6-3F*',"4B+"'G$E98%
@r8123
TCGACTTTTTCCAGCAGCTCCTTGCCGAGATNGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGC
+
C+$H$GF$G7=@'.;-+A,5)D8;>..*"'2+B?DH6"1+DG17$B!17A=;12/'.B0(E63A*-8G1G"E*=93E11)9(949
@r8124
ATAGAANGGCGCTGGGAAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCNACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCAAAATGCTGCTNGGTG
+
$$&*'$#+#(%+*&")&&)"$%"##!)'!#++')#'$%&!$$"")(&%!(!+$'+(!*&%)#+%"&(*!'*!%#''()+'&#$"$*%**'++&*))#+&('$%##!$"**&&)%!+**"(!$*''$'
@r8125
TTTGCTGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCGCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTG
+
4C>HD%<6!"1%'<1,4@1&"#0%>%H3!12:</6B!E":HA&081=7:**8'F<".@"7)>6%*8.(0*AC63;*:&F-G7=@$4CG0+7EB40#;>+B
@r8126
GGTTGATATTGATTCAGAGGTATAGAACGAATGAGTACTGCACTCGCAACGCT
+
:H'-H"@89?F,4+<'-)04,H&+AC8#,FA8F-<(;,BGB.1.D-?49;067
@r8127
CNGCCCANCGCATTCATGATGGCCCGCTGAAAGGGCAGTGTTTCCCAGCGCCCTTCCTGGTATGCGGATTCTTTCGGGAGATAGTAATTAGCATCCGCCCATTCAACGGCGGTCTGTGGCTCCGGCCTGAACAGTGAGCGAAGCCCGGCGCGGACAAAATGCCGCAGCCTNTT
+
$-&'E4DC?=6144F(&G:'<$GA4#A98*&")4)8F23#C84BB0%F)H2$,B#/=!(9C@'%5@#AFA2?H)>+78"?)DD&8(1D"89!B:&6A@$G>064B6*73B/0=2-%$D$+(*;A=FAG.H35D1#55;-+:"603H*+;>1'&)6?E3E*;?1?=!.%<@6/*
@r8128
CTGCTGANGTGCTCAGTATCACCGCCAGTGGTATTTATGTCA
+
E%0@DACA&8/:2(8/"1&)>(BF61"/<&6';2,/$70*B@
@r8129
TATCTGAAAGTACTGATGAACGGTGCGGTGATTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATTGTT
+
B'&#8()"&)+!6C)'B*%#&'!?$HDC919F)(50//+##*G)E62':?:%2;E:$26=?;#4G4BG&F,G-4A")'"#=
@r8130
GTTATCGCCGGGAGGGGAANATCAGAAGTGGAACGGCANATCCTGGGTGAAGGATACGGAAGCAGAAAAANTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTGGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAGGNA
+
:0>5C.B8'E+8=B6!@*B.@!3#8B"%>(?=9HEA"DFH1:3%3"H/2+5>!"-D@D/H@BG)85:5B6"7,*5"88/30'A&*74)!<*0@#"#F&%6-'BHA'(?A47/>(-/4F*73H31$'&$</.5%3B+0>9;>$90D66>)::625H:.3CFAB+7(&>C)7'&E%;">.-?B7+/
@r8131
GGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACGCTGCATGACATG
+
;:#$4C@0>+:>$E&;$=!4,)+G>&>(@)/.7H=*7;9$+>816&;:!9+:-&9557C>.#*4DD=+-(>"@A5'$;&
@r8132
GCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCGCAGGTGAA
+
@=82DB5<&,@D$4)',0+(,7<DHF0A<:1&C=G,AD!9$65*3!E+BG5CD5?57:C4$C+-*<:745$1!DH"$4!$=>)919-)!&1G".33#H.
@r8133
CAGTTCATTCAGCGTATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGCCAGTACANAAGCGGTGTTCGCAATCTGGGTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGC
+
'G<*%7B6FF(C&GB0A;6B'1!;?3D2"6<)?D,2B;B"(61.(8(*>=!7(2476,-1C,610/)('G)?EA&>1A$/;/1>?H(7761)A(/>7-1=-/27#H3--29!63C59;E?,%(8&*F
@r8134
AAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCNTCCCAGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGAAGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCACTCGACTGCTTCGTTTATGCGCTGGCGGCGCTGCGCATCAGTNTTTCCCGCTGGCAGCTGGATCTCAGTGCGCTGCTGGCGNGNCTGCAGGAAAAGGATGGTGCAGCAACCNACAAGAAAACACTGGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAAATTGCCGC
+
)),:.+E<A"<:+#F@$CDE-+)740/&2,)3H,>+70E1B=7-"+G=8+=DE=.A0$:D7H#9D*H")!/6?+*7@C0A1BG486'$D4A4.6(@)40(B-/(&/G78(D&D>>0@+A55@0<BA!>:5.3/*6H5A00E;<7$H8A+&&#B?D9B50=7?$C/6G'6"=0H9'@?A#!H7,$$768&A<1*+<F?C7@$341H89+F>@;C"<(.>AB-.D#*-<0B:7!C"71<3??/G-@%F+,-48&</>+?EC3CF)1G7##:?$9A>2;*E6G($//66)$6F<5D+80F&.3B>B64F/,ECA095@?B3=<%,F3+*D:D3H#+B+2C4-A%7F)7362!$=,%!A..!7="'E<1C)7@/G13&8$"/1((B'AAC-<;#D7)"+;H4E<)&/-=HH)'>6@96*52'.)>*@*E
@r8135
AGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGC
+
GD?@''F.&8>'"#*%/.=745:4#=+')=&!4/*6-E?/"
@r8136
GCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGANATTGCGGCAATGCT
+
$+%($$)(&#'!%+)"%!'&%(!%'"+)&')(*""%'!+!+$"#$+&()!)"&"%($+#*"(%)#'%*
@r8137
AACAGAACCCGCAGAACAACAACCCGCAACATACGCCTTCCTAACCAAATGA
+
3+H0/D'8#/-897!@%9/4H70'+B&D@C4$A+,70/H#>:$:9#1-80"/
@r8138
ACNTTGNCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCCGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCA
+
#"#+(+&$)&"*+"(!+#!"$#'!#)%)&(!'$)!)$)*#++')'!!#'#%'##$'+()#)!"#)**$''&*&'*)$++)(""#'&"&(&'%((+(%##'%+%$#&&+')"()''(+#)'#'+'%'%()'")+##$!""+%($#)++%(&*+##(###&++&"+&'#!)+&+&*++#+'&%)*%!!(+**'+#)$!%&*)!)$'+*!"#'+*+
@r8139
NATCTGCTCCATCACGCTGTANAACACATTTGCACCGCGAGTCTGTCC
+
%+)!&'$$"#%!#(*(&'&*$#%#+!"($"%'#+"(+*#)!!%#+&#&
@r8140
TAACGTAAAAACAACTTCAGACAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGAAGAACAGAACCCGCAGAA
+
A!-BA1)%5&<)G*D2F:AFDE>;+5<!B6=C0=3/)2<*0(;D@!'#A:7C0/9%2<1+):"0&EG(C3)+/2*+BA')$+5D&'
@r8141
TGTAATGGTTGCTGTTCCATACTGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCAT
+
=3.2@$?'-FDCB3.H'!'FF05:(<?A$;C=A)H&EGDD>?150>):+4F71=96!<B--0FDCA#&
@r8142
CCCATCCCCATCTTGTCTGCGACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTTTGGCGATGATAATGGTTGCATGTACTAAGGAGGTTGTATGNAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGACAGCTAAAGATCTCGGCGTATATCAAAGCGCGATTAACAAGGCCATTCATGCAGGCCGAAAGATTTTTTTAACTATAAACGCTGATGGAAGCGTTTATGCGGAAGAGGTAAAGCNCTTCCCGAGTAACAAAAAAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGNAAATCAAATTAAACCACACCTATG
+
F,85'>4=6@:-,*(?(E10%BCF0+;2!/G?$#%*'+3=A*%5!.!F$#8=E&1;&BGA(>7*&ED:+97/D8@>+496%86(F%-;-E8A$7D28F'E!28H-?632-B%C?2F&!*B6F/;!:<*2**"E?-FH:3>%2*'C7"6&))B(;!%!@$4<9F,'5G&"G16."H#+@,'5GE-8&,$9/6E':-@2!&C3G;*DC/8E<31$92:A7<54&D!G5/&<H>H$*?5;?2?.62&69/24(/@$-<2'&G(E>-*1DG#/8%2+G8C+#61+D$5&=-1+!E6'G*2F>1@+8.#$H@*A;G$2B%@"*-2B+$;--80H4$D!)F*GA(EH51"FFH=(6@.G<</%':A*497G53345C@#-+=A';;)@D2=DA!"=#!F&8,(A6=.+122&#FCG&8'@'H:&@(4/F34>DB""1'4<.A*E%F=':&2(.D&<!B88*/A1;$;)F9&7-3D1E#*.-@G#@7C;>*8C)
@r8143
CGAAAATGTCAGCCAGCTGCTTTTTGTTGACTTCCATTGT
+
+?A+G+7);@:7"F,/.62;$9A1>%D7)4'$0G7?83$(
@r8144
ATGGGTCGCGAATACGCTAAAAGATTACGAATTATTACATGCCTTAGCTATAATCTATGGCAGAATGTATAACTGCTGTAACTCTCTTGGCATACAAATAAACAANCCAATGG
+
G02H-?:?.8(#,B?7119A;'!7B-'%28(,A:5FHCC60D.70+1:@?7G-3),B)+;%C'B*<1.-)9+)3@C/!/&C#EHA"'CA0A%1+?!*315.68::'1%-;$8(
@r8145
ATAGATACAACTCACNAAACATAGCAATTCAAATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATA
+
+%!"&#'!'$+))(+*##*'(#'&(%&+'*''')**&'#$&+*&+%*++()")+++)'$!+#**%*+'*%+%!&#"$**"('+"!!)")(&"!)('!"%*$$")*)$&+"#%
@r8146
ANANGNTGNTCAAGCCCTGTATCAGGACATGGTACGAGCTAAAAGATTCGATACNGGCTCTTGTTCTGAGTCATGCGAAATATTTGGAGGGCAGCTTGNTTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGT
+
$$)$&%'#"+'$('*&$#$")$)&+%%!($'&#!)*#+&''($+##*%*'$!%+$!%'""!)#&(!+&(&!"'"$*++#"!#$%$!#!)&#&($!#"*"!&'!#&$'+"+#('$#'(!%'%(%%%)"$%($#!'"+"!+$*$"!'(#
@r8147
AAACAACAGCATAAATAACCCCGCTCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGNG
+
#?!B?H!#+14B0B3"(-4A==&#::4D53G2.+*'2*!B=?#E@'4!<)-8!'9-7)5+G*B$2"4)1-=C
@r8148
GACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGAAANGAAGTGGTCTGATATCGTAGATGGATGTCGAACAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCA
+
,C)F48$$@+031DHBB7.!>,,5&'6@,D5"G39H"*4@BA0&>%:CDF@G(:%5#<-1&:;$<3<-C@C@<93,F)H")F.>$&2":,7.-9F2>/E0G*"$2F'44?>;C-1(+/)#GH77&8>6;>C$$-
@r8149
GAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTNCACATCAAAGCAGTCTGTCAGTCAGT
+
018FG'@5#8+9$(4A*%&F*5?:.9'$>D!>C6+GA.&)'F?1,E3E-A'/D0$%'BBB./(#&BG.86?)"$)1&!*-"D:*1%F$+8%$F<2
@r8150
ACAATTTTGAATCGAATGATTGGTGCAATCACCAACCCAGAAAACAATGAATNTT
+
H1029>0"D3D&4>,:B!:34>634%-A>B!9;$/4)75B/H@6EF/(CH"'9#!
@r8151
GAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCT
+
+#+HB?60?AH*,@&1!(*1#@>-;8;*#">837;7;H)#H@F(A!1
@r8152
CAACACGCTGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAGCCGAAACANTCCAGCGTGAAGGTGTCTGCGGGCGATCGTCAGG
+
03A"076-"39<EBA@D%3)>@@+#7.AB$#9$&86F%(A4$;EB#3A&@&@HB%324!(GC#,E$==7+'7:(@HE"E)$34E;B2<.(422$!
@r8153
CGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAANCATTGTAACAANGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTNTTTCTACTGCAGGAATATACCCGCCTCATTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAA
+
6@E)30.>(/A--.0<F8"?#@..2-/6=.:;1:/E5(;$,8H!#85)B00-+$"#C94"BAD?D,B"(B=9?$=*<%H>$?&C;2;D%187913A7..)5+GG6D!C50%3D0.7?-/,A"5*?BCB9:=/;CG#H3==1FG@>6D9$.BC'$433)=(8H/<,H#-9/3!.A)!3+BH#/)&<=5>
@r8154
GTGACTCANTGGATATAGTCATTAAGCCAAAATTTAAAAG
+
%(H0?8$@1C"30;)35*5H@?)F,E8D8G23/H3&<B!$
@r8155
CGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGNCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGA
+
-6<C4<2"53:.'G,$&%@AD"A+H&-$84)??;A8//+:(4DH$9;',GB0%9HF8.1<*&388:*"<;00===?!225>=:AA!.@<<!!',F<1GA.@)$:6%FDGEBF51-5-8'&E#4@;,B;&@6CBB0-%+=D@2/*=
@r8156
GCGCGGCAACGTCCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTG
+
/,':=&+8<6%A2?518.A'=B85"@C.F825D?<G,15D?3227AD:$9A-3,301H99;2G?B
@r8157
AATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCGGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCC
+
'0"A0F6;7&$$AB/DFGH43*<>GH2'E($#70>4D'7<?9!*47)1%8A5-10(/(/=#-!:E;A6!708!D@)"8=*0)++-CA,%6#:.=3@41:45?,D3-H0G%*BF(F';9?G/C39394#GGC"27/##4"2
@r8158
TCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACGGTCAGCGTGGTGCTCTGCCCTTTCNCCACC
+
-$6!;-(',$&;H;A(C>C=.$;:'*/6,$"9(G(1E/63;#;'*HG$=)E&$+>+D584<#-$(
@r8159
TTCCGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATA
+
H&6$(#$G/D9E3D/A,9.#=11&7E3-7!&6E'C=*&5;-"
@r8160
ATACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGGCCTGGTGTCTGTGGGATAT
+
H-%<E1>H%'@**=E6A,"3:B#3B51,#A!!+.HC9?<8FE;)3(4!F(/F&?8&3@!.C">(""-<'7CE
@r8161
GCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGCAACCAACAGCACGTCTGAATCGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCAC
+
3"<7-//5,&+=3-%<@90"'E9+AFA+('"*,0#81#A1!,6--C!F$;3#+%@<4<8H#A!4/C(;!$AF5)<*397@5&D%10?@>H"=F%FE2/0>8+/#:)"!H1!EBFB,D&>5$3(?=A<5(F?"-3F
@r8162
TGGNNTTTNNANNATCNGNGNGAACACCNGTACCGCCTCGTTCGCCGCGNCATCATAAATCACCGCANCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCAGCTGA
+
$$)%%*)$$(%"!%&!#''$'&("*$)*#&+"(%)*##&)"")$('&"+'**+"()#)"**)(!''($"#$((+"+"*)%(+%&&$+!*$+"(&*'%#')$$#&+&(&+**&('++)"!
@r8163
TTGATATGGTTTACGAGTATTGCCGGCGAGNCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCNGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCNGATGAGCTTGTCCATATGACTGCGAGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTNTAAATCGTGCACAGGCTCTGG
+
1#6B7G/B&8E:-A)@)92$"&.-7C4=-@G>94,-/)4</-%F*@$#C7)9:>;D>'H?A"+*&F>*G.%-4D,3F*9-D567H"&!+*=2GH:>!B2$D&GC)+/BG-"!2G!AAD>B+?C90!3*-=A4>8#A%#!9G(B.$.AH,55D/*!E@DF6)AD8(D#$<;8-D>D;)C"F-'4/@C7%$2)%&C%*&6E"4)&,,?1="E!27-,A912H%$*28?4D.!5>B'(9/.#/,53=%3%$)=CH,@&?@+B1/3$FE2/
@r8164
ATGAGGATATGAACAGATGTCAAACATCAAAAAATACGTCATTGATTACGACTGGANAGCATCAATAGAGATTGAAATCGACCATGACGTAATGACAGAG
+
"A73*5$%"#>F''9AA97,D4D+')<>5386)5&3&E:""&>A:B)(!8>$#07<(/93--66.%'%:9/5>1(7!&4#;8,G?.H>/#A?2;>/",9C
@r8165
NCAANTNNTTTNTAATATGTCGGCATTATAAAAAAGCATTGCTNATCAATTTGTTGCAAC
+
&#)"$(!"%&$"))%((&%&#$&(+&%'***%+#&#("!*'!#(#%"!)&!&(($!$+#*
@r8166
NATATTTTAACAGAACATTATCTATCAGAAAAAGGCNATCTCT
+
'G5?-/FB8$<G4*;>-EG5(/+A!&?0B*0">C1>#'&A:"+
@r8167
TNCTCTNCTGNANACTGCGNNNNTACNTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGC
+
""'()#!!%*!'"#*$')'#'#!#(!%'+(&&)(&$%"+!&""&'#$!#&!"()%)*&*)"$
@r8168
NNAANNCCANNANCTNATTNCNANNNACCTNNANCGTNNTNNGANCANNNNTNTGNNCAAATGNTNNNGCAATNCNNGGNNAANNGGCGNAACNTCNNGNGNCNCCCNNNNNNNTGNNGNANNNNANCTGNANTNNANCGNGGGGANACNNNNTGNCNTNNNGCCGGNGNNNNNNANTANNNNANGNANNGGTNGC
+
#!#$$!!"$$""$$$#$"##"$#!!!!##$$!$!$#"!$#!"#"##"!$!!$!"$!$""##$#"$!$"#$#$!$$###$#!#!$!#""!##$"#$#!$$$#$!"!##!#!""$#$#"!#$$!!#!$$!#!$!$!!#""#!"$$!"!""#!$""$!!!!##""$$!##!"!!#$"!$"$$$!!$"$!$!$$##$!#$
@r8169
ACTCANAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAACTGACGACCCTTCTGTGGTGAAACCGGATGCTGCAATTCAGAGCNGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGA
+
(&(&*++#!%"*$))&"#*%)*''+%#+$+"(%!'(%#&!)%!!'#$)*&))"&!#(++#*"%'+")*"*+&#(%%'$%&*&*+**#*#$%'&#&&%%!#'+!(*&&'!#%*'%*&(#%#(*+"*(%(&"+#'$"*''$!&%!*)#)*+%%!)*$"$+#+&')$*&($!($&#&"('#)(&(#+("!#!+(('%*+)%+(+$&)$'#*!$+!)*+'&%&+'("%")"*!()($$!)#!&&""'&!'%'&)+%&&'
@r8170
TGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGT
+
='&?)&="/5G:E>(F)9E)(H=G$'C;0#&0E'"$A31&;4@@B,,B(H%!&4F#:G8C?#A30@D)!'$$:7"8;>1$1D@65.*'!>:E33
@r8171
CNNNNTNANGNGTNCNNCNATTNNGGNNGTCNCNCCGNNGANNCCN
+
##"#!#!$#!"$$!##"$##$$!##$$!$#!!#!!$""#!"#$$""
@r8172
GTTGATTTCCTGAAACGGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGC
+
?AH?6:;!7!!=8DA/E>5F!A1*>2F/D@@(6H.'6&9F5F30B*B2)$EC77,+<6/.;6/9.6E.HF.-3
@r8173
GCCTNAAANGCCNNNNCNNCAAAAANAGCGGGNNGACNANCANCANACGCCNCCCCGGTGTCNAGCTT
+
)!#"%&&)!&$("$$('!%(&&*#"*&(%())#!('#%''&"!!(&*($#'!"()#*#($()%%+(&#
@r8174
TCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTT
+
+",3?45GFC%<8!:F&!6!94>9)?:&161>H+@(*55)B<=$)'E;6/31B@F+;"7$24.*#,"=?(.29A<@?B=$*43)<*(177H!A":D!/A-8HE(:@+7(#G;*0@G4@B''"'<!/0@8+%0@D
@r8175
TGAGCGTGCAGCCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCCTGCCCGCATTGCGGGGAGGAGCAGTANCTTAAATTTGGCAACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGNATGACCCCTCCAGCGTGTTTTATCTCTGCGNGCATAATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGNGANAAGACCGGGATCTGGANCCGTGATGG
+
-<8G9/B+;</5HFF=D#;1A!*"/D<D6+2E8@AHE*3>H1CG%)B*)AEBBH31:?G@)F2@0(2G1D3@,8&F"C.7?&$E'DH+G81C+1*/19=<+1.F8461C$6!7.>./4D<8?;/>BE?@C87/%"*,C?/"A.,CG20-5>DA9'$9@=2&58,4,DF$79"*5,AB@,D!:?EHA>F!,21(26E)C9CE@!D7&D:>"8B2G#4#!#6E<'A/:A6/36.4%5!9/?(.G0EAD
@r8176
TCAANAGTCGGTGGATGTGGCGGGNTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGA
+
*"$+"''*$*!!($*('"%)+")#$*$$!*(*)$"$$!#!("!*"(!"&&'+$&"#*'%(#*(**"
@r8177
CGCTGCAGAACACGCAGCTGCAGAGCGCCATTGTGAAGGCGATGTATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAANTTGCCGCGTATTACGCCGCAGCGCCGGTCCGGCTGNGAGGCG
+
49#8-&..<+.%%0?3'>;+-)D9"1G$C)("!$%2>@(%F-E4+1*&5/B&8@/EF:C((F&F")4315E)>%G'FA%&$<!='CEG4.5%E8$?'G?6H-"H)8'/+DD+<"%5H=-&+5*CA7F7%G'@"'#/43")"3B,G*(DCC?+=:56G1-3(2#1&+31+3,C3(443,%#80-&#EEE*EB'*+=
@r8178
GAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAAA
+
GF@#%59=F!3F8=/<!/;')B43-A2<$A#D*&%E16A$
@r8179
AAAGCTGCGCCGGGAGGTTGNAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATTCTNTACTTTCGTGCTGTCGCGGATCGCAGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGCGGCGTTTTCCGGAACTGGAAAACCG
+
$%F#,,"$0+9@A-!G#E5.-&(C=1<08@%<!4#99"#/$A2D.'4@3.D;&9-<*=,C0!C%AA@7<76>F&*&*"1'($D)D@E-6H&5.H97!)#"C=CD@?25@'?7=DG3>:A=6--C3)'%)@.'16-A5;E'B(D/)<&*>E&'5!@8(!%GB"A.(EFH2:+*E%7,"?/"H&H*0A2"4B@5(90B@/<3.3'+E1%(75+@=$!3)E',A+5B>*G!,,#H<"$,=;97C5%;)'3A=6!0"=!9<(
@r8180
NNCGGGNCNTAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGG
+
$"(()('*%(&+'*#$*!*$)%%((!*#%'+*!!&$'!*%&'+&*)"))*'%$&")'*"&*&''!#'+()&%*"!)!"+(##"%(("*
@r8181
GGATACATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTG
+
$6.D:6A!F2)6:-$<(>&+1)=1BD))8!-6<F$59<32E9B>6";(.15$
@r8182
NTCCTCAANCTGCTCTTGTGTTAATGGTTTCTTTTTTGTNCTCATACGTTAAAT
+
"7#0?'"53+85'0D=9B:42>?'.G!&%3.)3$-")92;''4>?F;E&E)6!$
@r8183
ATCAGGCTTTTTTTTGTTTCTTCCGCCTCCCGGATCCGGAACAGTTTTTCTNCTTCCGTAT
+
,322(/D>F:@-0';/D5?EC5B#@4(A:-)<2'.9E$,1A'792B4CG.@3G@E>7E:5E
@r8184
GTCGCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCACGTCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCNNCAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATNCCTGGAATTAATCNCATTCCCCTGGTTCAGAGCTGTACGTGGAAACCATGAGCAAATGATGATTGATTGCTTATCAGAGNGTGGAAACGTTAATCACTGGCTGCTTAA
+
+E02EF1:&+%.CC:A19!+-5F/.@'"H)EA*&>*'?,5-&G*7,?HH='=/*,A"#E,=2C)15C3"F:>A@%3310G9+0H0#>-:,A1FDD2:2.0*/DF*>2#&6%F;;4?3:4?,2E-%:=<?6>46:?,/$D5)61+6HD:FA?1@G::,/!?)E>2"&DG+5<>65<AE7?,F1<'!3FD30///%9).8<'D4/91G5H!*(1'C,,1E3"&,>B2AA/=E>(FE;<G'$;7BG:<(;B56GB()$7$+70'1@=C*H#62<!D590+:5.373(,H9#;8G34("1)@G?)0'$?+(66B@!8%C>/?"6&:H!.E)>0=7+.BD*$(G*:<;5E)$/83=&5BB@$G=A/G,.*&.7:!))G2@#@&C;>D5;%4
@r8185
TAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTA
+
D*9F9!EH$#(*%:2@A.5AF!10(;C&$08A@C&;$*8;4(
@r8186
TAGTTAAATCACTGAATCCGGGAGCACTTTTTCTATTAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACCATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAAGTAAT
+
=,3$E2H#2#EH?'@C(B8(@(0D80!,B/351@-">;==H(1?+45)(<>08>-1@4"1)019!<61/5$0331E1F3#8"(%4>)&-BG53&)G%4":&1(=*8/BE8E%C5-E?E;?,&D04951/=,
@r8187
CCAGCGCCANCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAANTTCTCGGCATCACCATCC
+
75EG"A80(,7FB@0".'27H/)CB<2G6?3D%9<%=D6/,.,'=.*>8%EB1/%A#/(!-)5.FB'?1C%?H:7);
@r8188
CAGTCGTAGNTAAATAACTGACCTGTCGAGCTTAATATTCTATATTGT
+
(#+**&(#"%!'(!+('%#+%$*+"#"#'&!%($)('*&"%&($%$'%
@r8189
ANTANTTNNAGCNGGAATCGNNNGNNGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAACTCTTTCGTAAANGTTANAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGCTACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTANGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCGAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTG
+
*!)&!))!$%!'!('$&***#("&!"$$(+(&#(#"!+%(++*$($))'"+++*)"))+$#(%!!**$'"(+"&"#%(&+'"!"#*++!$&#+"+'"$+$)!%('$%!'&(*'%$'&#+&'(!'**+*!!*%)()!&$!*&%)#&*(&'!")")"$+'('%+$+&+##'"!&%'&'*"*'##&&%##$*($"%($$$!*"*"()&!*#&$+)#)*'#(((*&$$&'%$"!&"(#*""!"%(#(+(#+'&+!!"!"#+!&!%+!"$)$&()"*%!$!#"!'$$)!&
@r8190
ACAACTTGTATTACATTGACAGTTAAGCAGTTAATTTTATCACCTCTNAAATATANCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAANACCATGTGAAAGAAGACTTAAAGATTGATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGGATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGAC
+
6#F'@H='#F6GG1-%HB6(B=4<B8C'+=$#E<&G*'<':&:*"G25-C*F58?&5=-'&E@D!',&F%-CD7E>D/;D??@,:C+%D8F$A9@=.)?CE"E=/&E6.'$H62(!B%H-"55F:@4$.77EF+04,,'$58=7"C?,E.->%5B#A):A)!;B&-"B.A.636=3+/+B(&3H/-.)108%+,83CH%8@6?(,EDC=4$-(7,+=05>E4E5:A=%3,<%>>:!6#3";)>G5A2:90+/(*31DAD&1A0+99A0<-;
@r8191
GTGANCNGCNGCNGTCACNNTTTGCNGTGCAGAGAACTGAGCGCGGTGAGTGCCTNCATTGTACTCTCCACNCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAG
+
'&'("*!*'#"'%("'%"$$%)&()'&)"%+"()$&""&#**!$("!#'*(&!!)%+(#&)&#'*''#&&*$)#&$(%!&")#(%"'(&&*!%*#"!")!)#"'$)(!%%!(&$"(*%*!%((&*"%+)!!!'("+$#+&+#%)%"&!!)#+'''(*($)"&*#
@r8192
CTNTATTTGATGAAGCCAGGAGAATAACTTATTTAAAATTAAAAGATTACTCCATAAGCAAATTGTCATTTAGCATGATACAA
+
32E#<=G2,G*%@4E;H8#<0=H;$34HD:.-EG"A>+!-G/E'D=A0G81>+4H17E,;F42H/352>3!;@-%:D3,.3EC
@r8193
ACAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATNGAGCCTGTTT
+
)(@91;G&,EC4%6#4&?<;175(=;34%7C;=*9<B606$9%3C!9):#31:%40A"9%@(B6D.4!4*F3B";0
@r8194
TATCGGTGGCAGCCTGTTGCAGANGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAA
+
)4*9"'*#2!:/D/(4G,4=;?#(9BCAHEG9E""<F6,?<35H$:*;H&=%"8(41)6%"D%93#B-?B892@C#>,A!-98,+&6*;(9,6**9E>'<@)@7$&DB:,7@4057#5'35F*1,4;,"D0).G?-=
@r8195
ATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTG
+
<>%6FB8--E290".8':642>%5G!<.A!"'F',<0=5(F<?'%@$G;$D3)=)%%$4G7A3/D8;!B9:=*6@)/.6H-7EEE-"G
@r8196
GATGCCGNACATTACCGGGCAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGC
+
*:?0*?1.12#E.?<&*@6%,0.G=#4)6B9:E(%D/*!,18E&;;-*>*'8!7E77
@r8197
NAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGCTTC
+
'C*&C)CB?5(@&76$!!-)@&C$!E>;F6>1<@AF1>/0A.B2%4&.4,,$*(2@A!>-@:B!35=C0=3B/7#$C+8'9%$*D(<9
@r8198
TCCGGCACGATCTCNTCAAAACTNGCCATGTACTTTTCATCCCGCTCAATCNCGACATAATGCAGG
+
<&81+:%82#.!,&C'(E6+$E.5BD35#,03*<91%-5?H%();!>>3=3?"4;2433CB>.2(@
@r8199
GAATTGAGCAAGAATCTTCANCGAATTAGGGGAATTTTCACTCCCCTCAGAACATAACATAGTAAATGGATTGAATTATGAAGA
+
$-51!EE(*9%+#*G!(.A32+(<((/FF%C.51*F>+=5<./''55*+/D5@;A;4#"3-@*-+/'-@'$-):=4DDG-9-!F
@r8200
ACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAA
+
51#<2BH8+HE;&*"$+D257EA:+A'8%>-#'<:G<;)*@9:)?9*7&,<D/D@<C<3A-1<?0?C+G)(7*=.$F!FG7+)$F.%?G/<+$')F%E0
@r8201
CCGNGGACGCTGAACGATCTTCTCTGTGCCCTGACGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGGAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTG
+
)((*%*%$((#+"&!#"'++&#!(%%!'($&+"*!"(#%(#&"&*&!+!%"!!!#+'"!"%%!'$#''""$!++#$(!"$')!!!&+#!*)$)"+'&%$##(!#&#)#%+%(!&$($+&#&&((!#)&&)&!+'*''$(+#&+%*''!(!%#$%)&#$!(%%)''*+""#$(!**%!)#++(!+'"%("$
@r8202
NCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGG
+
($B2<9A8'(%%5++B(%2*>1%B1@96+G&/62-($)B)++44*<21
@r8203
TNANNTTNTCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGNCATGATTACGCCAGTTGNACGGACACGAACTCATCAGGGTCAGCCAGCAGCATCAGCGG
+
**)*!("!)&)&('*%(*&+&!#*%!"()%%#+(!)")!##%")++*+&(!+%%(($$(%&&'(++('&+%")&&$+)(&!%+"&*+"*$##%'))'&'$!*"%'+$&#'!'*(
@r8204
GAATNNACTGCTCACCACCAGGTTGATATTGATTCAGAGGTATAAAACGANTGAGTACTGCACTCGCAACGCTGGCTGGGAAGCNGGCTGAACGTCTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTT
+
"*$$$%(+!$#"")'*%#()&'"*)&%"!$+*!"(+!&'$")'&%)++&**#"*++%"&&#!'*!%$)*'!&#)#!#*&'#%$"+"'$+%$$&%"%"""*%*$$'!&#!%+#)')!$&%%&(%(+%!#"+#%#"(&")%"
@r8205
GCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGNTCACGAACACATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATNGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAANGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGC
+
E37.@1@-*2)#9F1*?@=%;+"65=<@F2/,@)>B"'D-=8BD$E8F&=2A0,C0>:4H2C!'H=19",/3(00@C#?5##-/<"4,8/H<.=*)-(::!7#BG0#3%;5*H")/F.F%E#D3G)41-76#7B=H/><E'!7<.1:/2(.6D54(2G/>1133H&0F0$3#&-'+C94E'/!,H833D$2325!!6676%36C>E3C;/+!;*?$<*.?$/%5+4!,',8:H@?A@@#@.=F-D#5=:*9*H.#?@=*C.G88A=.DF%-@&D>;#,<;98H%8,:5"6+!3=<;FF5"C%(=E'%+=81FB2C"@2"95ED=+5HD@;&@D(;?+C?76E.0*>!;<;/HBC:G7<8
@r8206
GNTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATC
+
(+()))+%"(($(*%*$#"$*!)&*&$*!!*&'+$(()+*"'*'*##$&)&+)(+#)
@r8207
ATTACCNTCACCGCCAGTTAATCCNGAGAGTCAGCAATGTTCCTGAAAACCGAATCATTTGAACATAA
+
500G6(AD7H66+1,71?,">=9!/79(7-.C:D,*FF-.C=<C+$FC6DG'FB#D+B@F27A74#3+
@r8208
AAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGC
+
-0GF>&;-2*7B99<A@4G&,"8&CF;'2/,>/.:*>:CF0@CGCB1%,FB15,E96->B'94.).=753B-,D-2-?F@0E$04.1;!B3@C?$<*%7H3F6G>1$-'AA1!C-@@3*CG+#
@r8209
GGGCGCTGTACGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACN
+
)B!:=:7)20&@(3)=?$4H0@0$?*,#)G67,%7.6!*#6A+<'$:#FCG:E"5*$<@DB$,&>,)'3)$9<6:+$
@r8210
AATGGCATATTGCATGGTGTGCTCCGTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTNAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGT
+
7D%;:&#B,7/G"$#4!&&,+;7!>/0H&<40A&/H/5!@1E'$0(&AF,G!!H7++?'0;B<0EF14'/9?FA,#$>6-(A&"06(7!2(8C2;>+>4AE.?8>.8>5+4#8*306<C81)/>:3C,.?3-A8+69E1:@:7%)""
@r8211
GCACTCGAACGACGAAGAAAAGAACGCGAAAAAGCTGAAAAAGCAGCAGAGAAGAAACGACGACGAGANGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGGTACTGGATTAAACAAGCCC
+
;(D7B2$0H6@18H0G&B39"EEG5*GH0>88;H0<(G'?F5.>9FD8>(05G?.53'1*4?$"C#6"5GF8@%9/A?(&$8HD/)@<2?;3&0&>+-!,'!5?:=-"G,:,!D:&'C&AB6E;E*;58',)0(*F=A:%+B4C#
@r8212
AACTGCGAATCATTCAAACTANTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGGGAT
+
E(:F8!5F,//?744>GC0-#76)($#>G61;@H/)H1#+:.?$FH#<';,"615$$04:(4A7;G6?1!8D.B4&A7$C&9H(8A#&G+&/2",&9"EA7!+?)=707C"$*=?9-D7'1;A-)6.62AD"2AB@/EE%D01,*566/)*5/35
@r8213
ACTTCGTCGCTGTCTCGCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTGGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCAT
+
4:4>7EDC3;6:G=$AA"H!*79D=B(B;&'@-9/1.G?*>73H?+/B7<!H6.F+!EG;'D;9HH&.&'$,%*/$43<37&>)4-2B!&=7F>4CG9#5#45%%?0<9:<D!(')DCB'H)1H;8:'&C4%&F<,4'H&>"5,D%%39CH:%$F'D"0'1
@r8214
ACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTT
+
3HA51.):4GGG9;<$@E3+;CB/B4'(5:.?85%3+2:)3*>59.<@!?#F&*6F%1@%-BF,8?<"B;
@r8215
CTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCANCTT
+
$5*G*C716F;(1>=1@92''.,7D'1A8$1"+G#9/!>)?-+A<D$B
@r8216
NGNCCGNCNTAACGGCGCAGTTACATGAGACTCTGCCTGATGGCGCTGTAATTCATTTTGTTCCCAGAGTCGCCGGGGCCNAGTCAGGTGGCGTATTCCAGATTGTCCTGGGG
+
#*""(#!'"*+%!(*&!(!'&%"&$""(!++")'$)"#+)''+#("))#%"!''!+(!&(&()%!**'++'##)#*!'%!)!$"#*!%*"+&&&*&#&()*#)#+(+%!!%*+
@r8217
GGTGGGCGTTGATGGCTCGTCCCGCATNNTCAATGAAAACCAGCAGTTTGATGGCATGGACTTTGAGCAGGACAATGAANCCTGTACATGCCGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGNCGCGAACCAATCAAAACTCGCGANGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAAC
+
?,,-C0:;:82:B;)93C/$FBDG72-A#9H3/#-%1&"E7*G#4'@G,8D%)6##>-4'*2ED/,GB!)=)'&701!7.@C<)126'(514'4B>C?7$-/1*22,5?<<6*8&61-5/@-A6G2().'B.;D$/F;0B'"'3";/)7>%5<@8;%&@@>+:3G)D3C,/B!*H;D").<%D15?1#769'=-=3#.<:!7C#$;2?D0<B6G?+?/
@r8218
NGGTGACGCGCCCAGCTCTGAGCCTCAAGACGATCCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGAAAGGGGGTTAGTGA
+
#!*=4="1;%):5*6:6#$9CCG3A7"3'D'2?313C:8?A7G-/=C0:$E"+C&3C<E+8C#,!;>'&&<9#5(4H0B%HG>G<49>%E+&$A6F,5A"@)</(<=+(3-&9#GAB<B.%+5<#2=0B'82E%.;#
@r8219
NAATTTAAAAGTGNNNTANGAAAGCTCGCCAAGGATANTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATG
+
(&))$("&()'")#!'%!)&**)&%)!+(+'"(%)&)%*")!$*'))$"+&&'%+$%%"(%"''#('(!++$!%(&!'###"(##!)&+#(
@r8220
GCNTTATGCCAACGCCCCGGTGCTGACACGGAANANACCGGACGTTATGGGTTAGCGTGGAAAGATTTGTGTAGTGTTCTGAATGCTCTTAGTAATG
+
**%%&&+'$))"'*"+"+''#$")$'()#)*!)(%!&++(#&"$(#%*!+)"!#''&"*&+(+#)&(#*+"#(%!%$%*("(*'+%$'*(*))""++
@r8221
GCNTAACGNCNCGNNTNTAGCGTTATTGGTATGCGGTNAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAAT
+
**!!)*)&**$&*!%&!#%$+"%$)+'+(##&&!"%&%)%*%(!%*#*"%)!'+%#$"%)$#*'!('!(*#"*+#$+(+'##%$&&'(')"(*$!$!*!%!$+)#$%*(*
@r8222
GAAATTTTAAATATTATTATTATCATTCATTATGTATTAAAATTAGAGTTGTGGCTTGGCTCTGCTAACACGTTGCTCATAGGAGATATGGTAGAGCCGCAGACACGTCGTATGCAGGAACGTGCTGCCGCTGGCTGGTGAACTTCCGATAGTGCGGG
+
16?-<F@E*(8/'C:9'5F0!*(!78!;4!6/G&+A9G&8A9+F-*:?;7622&90(F:?>.*!B34CH$;>*,B=9@9')%ED,(CD5#,6A%<#;;%24,+'2-@E8%9"0*)A&>G>>"/-8'BDF(7@2,"HA$-8#231*/A$'F*+9?613'
@r8223
ATGCTGAAATTGAACGAAAAGCTGCGCCGGGAGGTTGAAGAACTGCGGCAGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGC
+
H7#'<2AAEG2&*8@,52BC;676F(,H86>GA)=A2+=$:5'4)?.F)F8:F%?<5!<9%@.>:*E#=/"16'F@E->:E6%<=7$@(3,GDD2*
@r8224
GTGATGTCAAACGACGCAGCTGACTTCTTTTCTTTCACNACTTCCCCACACCCAG
+
;=@(GG,AF#"=$$5E'>;+;8/<9E88"-7C4HA%.D%23$"=5)*G!$.%=!8
@r8225
TTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCCGTGTTATTC
+
-?@>,7&EBA>)C:4>4,;/8"*91=H-?H!,6A-8+!#H:G&78*"A,?/9#?#)D*-,#'#6C=192(=C-4&5:<B38%3/!7?
@r8226
ACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCNATATCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCT
+
7B%'*&6A),F1?$B=.0HGF;(E/><+)(+!EF6$C5H@4HA?2"FB/?4).5F>=?*AA,@)%H#10,6314H:=E98(+@:3$6#D!07'/FA<G-C5C$!A;9:$<F.E3E'>3*>63;;EF.H3
@r8227
TACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATA
+
A*-341%,&'!0%("/?7A("=7+(E?6D)'>$>%:=$;9A3A?,)-G5$#$
@r8228
CTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGC
+
<>/*6@2'D(*EG3!G>"1F(7%$0A7875%>$'&&9!?C6+67"B)="(G;)0/*:G:*@8'#8B@C.A3<G'-4(%G0:26&+A2-?+;?!H1"B&=&9C:.%DE;90E92$!!7A!
@r8229
GGCCAGCATGCCACGTAAGCGAAACAAAAACGGGGTTTACCTTACCGCAATCGGTAC
+
@-/'=)BFB.-=19-:($DDG8(6CF$56A<,"E6?3-%-)1-*18$4'+6-BAH1G
@r8230
TNNATGTTACGTCATAAAGCCATTATTCAGTGTGCCCGTCTGGCCTTCGGATTTGCTGGTATCTATGACAAGGATGAAGCCGAGCGCATTGTCGAAAATACTGCATACACTGCAGAANGTCNGCCGGAACGCGACATCACTCCGGTTAACGATGAAACCATGCAGGAGATTAACACTCTGCTGATNGCCCTGGATAAAACATGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGA
+
#&!;."*)G*?F0)=).1'69EGD@3D)%24$,)5:DH?(H;#@,H&(9%4,>5-6!'5,4C#<!*!$*3H>E=%E:/@F:9-<B+)F4+/(:G,2A*%#G7G,E$@H)0%$1)GE<*"E.9B%9+*&C/-!&9E=%8$EC+!3="AEB*#.,4"EA09>:*)#C<B8)(,+'A2"D$01:3C9"7:-,;<H<96"<;!EC!+"--2B'!>);!>/+C1F!/#B@>+$3D&?&3B4++111=)"3F&='5#2-&,''!;!A.:772
@r8231
TTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCG
+
,G>A*C#:16&9)7$H*#@+3)=(0-<D(%+65G$?>E/(4E38@?D$G?E)&>%">75F-G#9)C3@""0'*26/.F0>G2,.!C*"1!G#>."4(
@r8232
GTNATCATCGAACTNGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAANACGAGTTTGGAAAGCCAGTTGATCATCAGCTGGTAATCTGGAA
+
#*!+(!!+)+'""*('%"&!"*&("#'("))$+&(%()("("$**+(*+!))%!%)&#&*)#"&!)##%$"%*&+$!$%(%*"!#*%$'+#)'""'#*$&$#%#%))#'&(%!
@r8233
ANNCCGGCGCNGGNTTCTTCAGNATTTCAAGCTATTAAATATTGCTAACAGGTATCGNTTGGAGGCAGGGAAGCACTTGAGTGAAGTGAT
+
"!"%$&!)!(!)%("'$*#)'!!'+)$'!"+'($+$$(+"%&%$!(**)(!#!!"&&#'+*+&#&++(("%!'')%#+%+$"+#&!')"%
@r8234
GNNNGNTCAGNATATGGAGNNCGNCTACTCCGTGTTTGAGCAGTCACTGCTGCNGTATATCGC
+
')$$*&*%((&'"(")%)"&*)'"%*)+'!"&+***&+##%"#+%$$!%)"$$&%#!('"#('
@r8235
ANTNCGNAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCAGGCGTTTGACGAACCAGCCTACCCAAAACTTGCTGTCGCGTATCCATCGGGTGTGCTTCCTGATATGCNAGGCTGGACAATCAATGGGAAACC
+
%%!%(("&+$%+#))"*%%")'*%!##++!)(*+$')))$"$))$$$)%+")%&(+)*$%&"&($#*$%'&+"$())&*%'*)*$*"''#"!+"'&&$!)(##"'!&')+'%!&*'(+#+)%')#)+"!%*&$!'$%%$+!*#)$&*#"&#!+#$)*+!%%+"*!*+)+$%'&(&!(()$&"*%#)(&(##"))&%"(""#%*!+#*((('%(!&$+!($'()!%*
@r8236
GTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGGGCAGCTTCCTCGGCAACGGCGGCAGNAAATTCTGCCAGGGCGGCAAAAACGTCCGAGA
+
$'=(?/&C($=&=FA=(9B*43!7H>;06>G@2)0D@>3-+!")='1$50'G(345?'$DH-#%74>4--".7B7G/E*9*0A$5A@9>H<(6HE(H.<4'/>&#>%)=-89?"2B/"H8A"9,=$<>C?)<!.'<9747-?:2-'B+7
@r8237
AGCAAACTNATCGCTTATCTGCTTCTCATAGAGTCTTGCAGACAAACTGCGCAACTCGNGAAAGGTAGGCGGATCCCCTTCGAAGGAAAGACCTGANGC
+
;#6/9%@<2G)!E9))<+5B(;!36,9BB<D7=D5;*?5"H*/*21&!D<''!HG%D/%7=7<=<!/6*!;H$94+(0.?%>39GCEF42;"7*AE@78
@r8238
TNNATTCTANGCNNGNGNTGCGACCGANATNNNNNCGNCNNNNNANNCNNNNTNCTANNCATNNNNNNNANTNACATCCNGNNNNNTNNNNCNGNGGGGGTNGAGGNTNGNGNAGTANNGCNNAGNANNAGNCGCNNNNNN
+
"!#"$!$$!"$"$"$##!$#!"$##$$"!#!"#$#$#"#$$$"#!""$#"!!!#$!!!$$"#!$""""!!##$#!#$$!!$"##""#"$#!#"$!!$#$#"#$!"#!!!#!!!$!"""!"$$"!!#"$"$!""$#!$##"!
@r8239
CCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAAAAAAGAAAAGATTATTCGTCATTCTGGCGAATCCTCTGACCAGCCAGAAA
+
2'44<8.?B8&3$"&G-4"+'-==?.B;73.$*('HG@1#'B4((&%0B#&7A*H233(G2.DHE2A$(-*@/4B6>/%4+9#<6/E4)82AC(8<!9&>,H!#21:F89B"H4*>:*;$?=0>A'-H.2571E*"-
@r8240
TTCGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGAGCGTCGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGGATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGACCGCCATA
+
.BH1'44)5*>-$2759;#@5;(3#9;->5-#$@))-).4#2D'<-H54>+=-;;HHF0D"!(0+(A6:G1H(=/0#B4=E=A(7AEC-,#11-"!*@0D8'@,<0D%?>-"102C@D'"H!B2'7;7@&4(0%?6H<*457:!8=+/4"C@E85/:8#=!</159;)7<?@%1;.0HF44>#"C=*':<6G/2!-%G3>>D87CA;#2G+9@<=C#5)*8E4%%<G?7.2)@H8;"9"92*A&>E.
@r8241
CTGGCAAAAAATTCCGTTGCAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTCCGGCAGGTGCGCCGATCCCGTGGCCATCAGATATCGTTCCGTCT
+
(3.9C;#=BB#:*A*D&1)B<G<*$/-CA@D*4"8,-;>:G59#CFB75:C>B>2(>,E#A-D56H:0?7;C!@>?:)+0E@88;C&H)$%?FF+@>5,/"0:7:0#1
@r8242
AGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGTGTGAGCACTGCTGCGCAGAACTGATGAGCGATCCGAATAGCTCGATGCACGAGGAAGAAGNTGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTG
+
86GC="5!0>4C?62>=7<A;*39#:*B:,3,9).+=&7"$-15/BC)A-89=9B;4')"7E%%'4%D3,G1A'0)0=4+!)<$@*%?CG6-603A/?<,$><"&@::,6C",!6E*2=87%,DF<H*A(70*3-*/,*(AA<3=(0./H89)E9(E03BHEE:H9;"&8?CA3"**9+&%1EG;%3:$=?;981'#050%3+2D/G0?-1:.HH41%D("B&!3(2;.9":*4"
@r8243
ATGTAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTCGGGGGGAGGCTGCATTATCCA
+
'H$9(D#3-=.@2..5%<G+H")"=A,0.9);5GB?-9"=:G/18G/98/ACB<45FE!*>A/6+!C*<1E!2D1'B(9!>#>-E:-AH1*"D,':CEB=(*6D24;-%7.E8$H&A3GE2@21@5509F-"G?=H>.!B!$:8'1%4C==!H"83DC
@r8244
GANCNNACTGNCNGGAGAATCCAGATGGATGGACAAACACGCCGCCGCGAACGTCGNGCAGAGAAACAGGCTCAATGG
+
!*%*$!)*(!"*#+$'"(&*&$$'"*")!"'$&!"#+)(#*$!%$+*&%&++"$#!*!(*+&&'$)"&!'+*%"**!+
@r8245
CAGAACTGATGAGCGANCCGAATAGCTCGATGCACGAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGTGCTCTCCAGAGTGTGGAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACT
+
*9!E(8:&)+%@33037D0";,F*#E%"<+F@)<FD9!37"*D40!@/$>*2.<G77?./9G70?,@0$;$!:A'&*#'!9E)5+39#+'&E+2H+1G2)A%EA"@F56<010)$."&*5(:71(1++AC+/'!<630)<5?2FGHB.D3?3/H%2(=>8B",'3&%'4=)4!((%AAC&H5@41<)49!"65.1@1E#*'D--@-E<!5=>AF=-$F$@057;D%(4*$,,G0!GGC=DH@9!1H<@
@r8246
TAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATNTTCATCGAATTAGGGGAATTTTCACTCCC
+
9*C/*8&<G01(3HG*C?G;15H11F&?=G@=H--B9/.6'2&?6*"B"="@;,8:;11A-7-5BBE-<@3:(%--"<-FE7+G,,1+:D?@+2FB!=9@G88'8(+16/.
@r8247
TAGACAATAAAATAATTCCTGAAGATATTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTT
+
&/B1EG.+97'##725$4$"#H4A40>("<H0?"6F("4"H0#7A8D)$1#*(2C6<(!?>G'27E$6G9,"67.0GA":+:)B)1=:/C)1@6'@2)+++0HC1FA%+F8<,@%;69@@<:
@r8248
NNACGGGGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAA
+
#.,0%D&,0AE07?",(#A:E.&H=$%-#(=.HG$,D)CCDF3$7-05%*(08G4$8#*C>$5*G;F-+H-8:#:=75$'*+/(=A2$C&6&&3&,D)9"F(GF'8-A4'1+:E
@r8249
ACAGTGCNGGCTGAATACCACAAACAGANTGAAAGCAACCTGCAACGTATTGAGCGCAAGAATCNGCGCACATGGTACAGCAAGCCTGGC
+
=3=C$+;-@*7B2-'=#>BD#88B1%/H+;E11"::B<F<?A:7$.@45,H$(&'5?/4!.;H;4A(HE1@:G?!(3);C<H4*;%6C;B
@r8250
CGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCNTGA
+
B2713)A4"+0'>:)5(E%FEG,*9;C@(""2!?B$B@EB7?)7B(D:"D0@D
@r8251
CGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATNAAATATTGCTANCAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAG
+
,:??9+DEG3!E.G@EHDD16-!)&6@CB<(4,922>DH!:/6A$4*=,;GG>)DC,1!C3)($#D(7;&(C4+@+'3%:#;0F$@/?7+D8'54=C6@G293)B*:B81#(7-4
@r8252
ATATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCATG
+
G(EE8)2;>F&+<<0:?$E60,$G?>6)C>D=&@2!;1<9>8@3
@r8253
GAGCTGACGGAGNATAACCCCAGCAGACTGGAGGAGTTTTCGAAAGAGTGGAAGGATGCCAGNGATAAGTGGAATGCCATGTGGGCTGTCAAAATTGAGCAGACCAAAGACGGCAAACATTATGTCGCGGGTATTGGCCTCAGCATGGAGGACACGGACAACCTGAGCCAGTTT
+
;F#6$60>>,7?:85><@8A*H!)7-29B75:,$="G9**04"BA.+8/?/BA:69A/(6$"'"!(#.B)D5.G#//)>=*?,(FG5#)73/.&=?@?;A%7)3#H!6&4"57,B;AG?F7"?&""<;!/++E,GAB=*GE#H>//B,="$E=G$1G0$A=7=3BF)3:-GE<+
@r8254
GAGATAGCAAATGCTTACGATAACGTAAGGAATTATTACTATGNAAACACCAGGCNTGATTCTGTTCCGCATAATTACTCCTGATAATTAATCCTTAACTTTGCCCACCTGCCTTTTAAAACATTCCAGTATATCACTTTTCATTCTTGCGTATCAATATGCCATCTCTTCTGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGCAACCTTTTTTATATCCCTTTTAAATTTTGGCTTAATGACNATATCCAATGA
+
9?H;.4"+'!C&*F<7H,?!;2'1*B+?@CD*749=+.81;*C<+.D-*96!%>5DF:G*7?)D5H+#-%#%-$:#H9+5F7=!3G#)"FD73+%/%);?:"3%5H=/79)C'>#,;-28C,;70B3B=+65=:B%B'@%G1<#G=BB.C"#(.,.)/9'2#7"EA@D0*(<@,+8/!D$#=109B>H<8#&:%DA>9>1=2=G$("E&0:&%'!9H:->@,H(?"95,6*A.F?/.)7,&E.*+8<-&$8/F66'3?GD*5H);F(;-5@G),!;?/:4$0*,'H;.0:,6.2843E&6+*C$F!C?82'G".*#!&FEF->A'66D?3@BHF#G9F-<B%><%!G&%1>;A2G=7C8:04H5!"4E/20E.&"
@r8255
GCGCATCGCNGAGCAGAAATCGCTGAGCACATCCCACGCCTTACGCTGTGTGGTCAGGTACG
+
03A=6D=:"%<<9!.@!H&3'.-%G2CBG!D::?!AAB@>&&:/>?0:'&GB)D0*?>$#.1
@r8256
NTTTNANAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTNGAGGGAT
+
##'#*!#++!'%!%(+#%)()(&("#&)*!)+"*'##%$##$*%*'*)!)'+%##$#%)!#")')
@r8257
GATGTGCAACCGACGACGACCAGCGGCAACATCATCACGNAGA
+
E?-/C<6$"4"<>C$9=D@9F,..$9.$H#C3EG38850:>,*
@r8258
GCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTCCGTGAAGCCACCACCGCCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATT
+
H%1<(3<$88+D@/FC<H<ED-@>7<:G7@#9A%*5C5B+361G%ECE(EHC'!6%8,++:%.F"*.(9C3FG>(1:9+:@9!:/0F=.D7+*0;&A(B,"@>:$)D<56<D:=#!EE>C&?,4?8H#76;>0"4@B5F+FA8"A'9*C/3.#+=7#3&>="E32!E#$2#2G.EE5=C)'*"*%%:-:BG!>)*7GD@;$6,77&)*(0E0,-7&FA77#?38)A/<!21G;)3CFF;+72B"0/:E#E8<+'D8%63A?##G,78/1599.010AGH:5*2=E8=9"3=+$*#+E=7B,/H2$?<!'/*#(G#+&)E0C!@*F(4E0,G6.D1H@74'>7032@4(A#;F(352*)19BC$G.%H#,
@r8259
NCAAGTTTTNAACNGNAGCNTNNNNGCNNACNNCANCNCGNNNNNGNNNTCNGNCAN
+
##"$!$$"$$#$#!!"!"!!#"!"#$!#!!#"!$###!#$"$#!!!"!#$$#!!"#!
@r8260
CAATGTTGTGCAGATCCGGTNTCTTNTCTNCATGCAGACATCACGAAGGTGTTTATGTAGATGAAGGNATAGATATAGAGTCGGCATA
+
?C#*=2BG(:8%H()/=:F18)!>:=3;,%DG-13&:=*'.5)"0/4,?C*'4C12:.=2&=+&D-H>5)!G!=<7+85$!EG3./&G
@r8261
ATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCG
+
+2B;A+G'$G7*C!3/@208"E%2"@6((52,;)5?2:F816+-.!.D:D3@':;755>6@8&&F&*74D5#<2<6G!$33&&-H.DC
@r8262
AACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTGAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACNGCTTCGCAGGCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAA
+
4H3C)<4#E4D+&-H?+##74&%7E*7'F3E,;63;$.&D5B1?=?6?40BA7.(&F+G.*.C.*+1'4',,8G$,4.!D"*2/1)/=%0".<,:0#&@!<#1(2$8&H((B>337'<;82!06D@*F==4-=-.H++C;9&G.?#300;!2554)%-(
@r8263
TNCCNNCGTTTCGTCNGTAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGT
+
(#$('"()&"&)*$&%#!'#+%!&))**)!"'+)'!*(")#+%$')))%'&)$&%%"''$($$!
@r8264
AATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATT
+
5E#/)5(C"?)H=A?+CB1G&7FHHD8#F1C6(-*B$:$3#7@:B2@0.=3"<:,,"&9
@r8265
NGTCGNTTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCG
+
"*(%(%+$"!!%+&!%%')$*)'"($+&*'((('++)'++$%"!&+&*)'#'%$"!%$'*')*
@r8266
CAATTAAAAGTGATGAAGAATGAACATCCCGCGTTCTTCCCTC
+
0"%(0<C793=(9/+<H@2:%B#4!@A<DE->$&=#;>%D48'
@r8267
TCGTCAGCCGGAACGCGANATCACTCCGGTTAACGATGAAACC
+
GA?C=F**(FG(D>%9!0FE)5<7/3A%EE=F/;0-8'+"B!?
@r8268
GGCAACCATGTTATCCAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCNAGCACCATACTGACACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAAGGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATCCGGCAATGGCGGCAGCCCCCAGG
+
<!:#=F;H>:!!'"+6</G:FE)>%8>"94+(;8D%$(,FFH"D+:)HCD+A=E><11G&@E%6EGC,883>1>'71>G3$.H2C>74CA*D")4:6G":G7,:%4=-+0%/=>7F7F16&*!.0A56,7B$0+/DF<#/+FA6F"#84F@*/@*1%'E-1GFD+7B@.)D)2!-:A&!5='3-&7B+76DF&-"'+G><#(#18B#F/G),*/E)C=#4A7;C993#)>*1F=0
@r8269
TCGGATCGCCAACAACATGCCGGAACAGTACGACGAAAAGCCGCNGGTACAGCAGGTAGCGCAGNTCATCAACGGTGTGTTCAGCCAGTTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAG
+
F03B)E1<&9@@"8CG;'G?5!+FD4GFC=0%(7.6?D+6491F(&9$+43B%!8)C#;!!BD&?@3G2"=A1//?$'21$=0F9/69+)/H))2(.DC-):$0A!12;)F>$6..$/?+%;B*'5$*9>=)+"2$A
@r8270
CTATTANTTTAGTTCCATCGTGCCGCGACTGCAATATGGGAGAGAAAGGTCAAGTTTTCGCAGTAGATGAGGTACACCAAGCGATTCATCCCTATATCGACAAGGACATTTTTTTTCGTGAGCAATGGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATG
+
;@/.G-?*?<.D;8+.!!8E29A:$#220CB#=?H&8G--<2<.-CB&:;EG+>6E325(6:'B.@)*%?@)@;'8?BE)7@H&-$"?B+F$E=$2@0(-A1(<+3-1?E'09-F'C<D@(A>H:57D9-4::6&)!+D.(0G7A*#'/49$>,@(%6*61$'8)*:GH8*2(2/#@
@r8271
GNCAGGNCGACTNGTACCCNTANTGTCANCGTGACCGATGACCATCCTTTTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGGACTGATGAACGGTGCGGTGATCTATGATGG
+
"!*!'($*(&(&"))&$""$&&#"'"&$#+#)&(+$'$$*"+%+'''!)&(''"!$!#"(+&""&(""'*!"$&(')(%!(+%(+$#("+#)*+$*"'*&&)#)+!#*'%)&+#*)+()#&''++)&+%#!*&)+'((*#*+(%%$$"($&$##%*)$"&%+))''%!#%&&(&'
@r8272
AGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTTCATCAGAGAAAGA
+
EF<2;"?-BF6@$0EA0,H,G74?-DD<?C$A0B#<$1%E@&,86HFD0"!9*G
@r8273
GTCGNCCCACAGGAACTGATCACCACTCTTCGCCAGACGGCA
+
+"*1C3)D*/&6"E,11#C92.>:,1##6@>C#'8&9?G$0D
@r8274
CATCTGTGCGGNGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTT
+
76*=,"$)3G(->!,(0=D(6>F7D=:*#5/A(2;?CDC%7,8!CG$3H>HB5(?:B3%<G7$2"5)&A4.6)B01H%1/>!:$2',F76%(33*!&
@r8275
ATNTGGTGAAGTTTTTCCTCTGTNATTACGTCATGGTCGATT
+
*(#+"!(*$$'('(%"$$+%*!"%*)##&'+'+#($*&#%*$
@r8276
GCTGCCGTTGGCATTCTTGCGGTTGCTGCTGACCAGACCAGCACCACGCTGACGTTCTACAAGTCCGGCACGTTCCGTTTTGAGGATGTGCTCTGNCCGGAGGCTGCCAGCGACGAGACGAAAAAACGGACCGCGTTTGCCGGAACGGCAATCAGCATCCTTTACCCTTCATCACTAAAGGCCGCCTGTGCGGCTTTTTTTACGGGAT
+
))-)9);(H$:'678*);;,"*2'B5G%!**$B>7>!B$!>H.+GE.1$+&A9):<%3<%8>%AE?&0C6-9*(::0$#G8CD/-)E!597,%D!BH;G%&:/?<BC"-E9006->(6;(?7CE@0!;(/5%$;5B9-;!H>C.'3?4>,@/#E,:.)",!*07):00#5*@H3=*DDF.D/-->30@.+=C5,.8C>F?@<3$@31-
@r8277
TGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGAAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGG
+
G35F/*-@2E&;'&35%C<->,&,>@5+8+0*=1!B9#&$86;A?8/?>1?@F-7@2&!88-(00<$2);G#/,./HA'2(-7=
@r8278
AAAAAATCGGACTTGNCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATGAG
+
,/85)4CH:8)):G2?H.;"@9@0C"8E6E?3--+'-@C?'"!C'E6<D$2",DD>
@r8279
GCTTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCANATGCGCATACAGTTGGTATTGGTGC
+
;%F917>D76G/"H"5D#(,+A7@$9B&H>%/9;7%+06A..E899D:E#0H-@.@!B0H3B0;*=D9*$(,@1;(63F8"@$">#-@@;E?F$:AG$E-E
@r8280
TCTNCTGCACCNACGCNTTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGAGAAGCGGTATGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCGTCACCACCTTCG
+
"(##*(**(%'!+%$'#&%&)++#"()!$$&!$+'')+'"')$$+#&)+%&)+$+)%#!!)(&$"*#(&!*!))*(+%'!)+%!"%%%#%&!&!&"##$%+!")'+*%'"+*$$%+%'$*)$&)&(&#"!&'#"'$%+#)'!')%$%$"*!&+!'(&)')#+$"*%!!*)))+$
@r8281
GGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTNGTCTCGNACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTAGCCGA
+
D<12>#69=%9:CC@C?!@418D67%:<D.*;,2:%!&=:.%!E%0=C'93!:?;G7BH#7A6(?1D-+:'B=8+#6',F?A71)8>.?"
@r8282
CAANCANATGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGANAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCNTTCAAATCTATAATNGGTTTCAGA
+
)$&%&'"+#)(&%%#%"$'+%(*&'$"%*#+!&#*$"&"*"##'+"+*%#+*#")!&)+((&#"%#*"!*%&(""+&(%&'+&%(%#"")(&'**"&+*+*%"#)+**)(*(#(%$%#+%"*$!%"+"()+"()$(&#&+"++%&+!!)+(%'$)'#&*)(%!*"''!'&")&&!*+*#+"+$('+#(*%+)%*+&$$**($#'"%))'!"$')++#%**)'!
@r8283
GATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAGCCGCACTCAGGCGGCCTTGATAGTCATATCATCTNAATCAAATATTCCTGATGTATCGATATCGG
+
&+!(("(#)!!$$$$$$&'!*$*'&()$#$$!%!%(!$))'++##!)$$+)*$&"%$$!+!$)*+%!(#""")(($&*)"(%*&++(+'($'$)+%&$(!%'))$$%**"*'
@r8284
TATATTGTGAGGCTTGCATAATGGCATTCAGAATGAGTGAACAACCACGGACCATAAAAATTTATAATCTGCTGGCCGGAACTNATGAATTTATTGGTGAAGGTGACG
+
+1=/*.!(!%3-(C3*@$H:%3B,6.4%&'>@'2A-755%%4,-/F%GA1,F,=(*D%2=(FD'#<#<2++4(9:.<:5C>GG0+&"C@$6=')/?";C###3H#>21
@r8285
GTGGACATAGTTAATCCGGGAATACAATGACGATTNATNGCACCTGACATACNTTAATAAATATTAACAATATGAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAAC
+
>6*?B-)=2=4D,>58'*F2#)D<&?10)%2!.((3>,C9D&1E@D8!&9GBE9(C'%:/H0F$(C)7-@;"886*9BDGEC0<B#?F59.2>5((C'3$G.2%4D/#%1.H?0*8<,A0?$@H3;!,$#9<
@r8286
ATGTGTAAAAGGCCGCAGCGTAACTATNACTAATGAATTC
+
?8?&$6/!>:#1+&20='$E,B;%H)"%?"C)E#0&=C@#
@r8287
TGTAGGATATTCCCACCTCCGGTTAAGGCTGGAAGAGAGTATCTCTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGAAGAGGATCAGAAATGG
+
'(#+)+'#*'#*"!(!"%(*!+!)*!(*!!#$$'+'&)%&%#"*(""((%)%'+!!%'))'"%&("(++&'#+$%&%)*&#!+*$&'$&(&"$)$")+(*#'%)!%()"))'#&*"+'&
@r8288
CCNTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGNGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGNTGTCTCTGGAAGCATTCAGAGCAATTGAGGCAGCGTTTGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTGGTTGACTGATCACCA
+
**+**!*!*#%&(!%&*)$&(#&))#'*#%!#!#!'*'%#+"$%+(%%#$%+!'(%%##+$%+$&$*#%(%')!"+"(((&%$**#!)'#*(+')+*)'"*$##'!$#"$'')#"$!$**'!'+"$)$('*)%#(#""$"$%*%'&!*!&+*##%'$*#$%)"%+'&$'$"(%)"*+*%%#'
@r8289
ACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTNAATGGTGTNACGCCGCCAGCGGT
+
G8<;"+*)850C7/2F'D(:="$@GE%B+H9F743!$9!'C*#-*,-C$(&0.3,=>(4=4?%F;!H!&*@8>>DF0#<&#*=;9F)/3@;E+?1BDC"A4)3C
@r8290
GACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTACGGCTCACCTGCTGGNTGCCGAACTGCTGCGAGTCCACCTGCACGCCGACCAGTGCCGTGTTCGGGTAGCACTGTTTCNCATCGATGATTTCAGTGTATGACGACCAGAGCGTTTTGTTCTGCAGCTGGTCTGTG
+
#*+$*+!"!+&&"))!!)!!+#"()('"#*%&++&($!"!))'%$$#'+!$&)(($'(((%&*+'%%++%%#*%$("+!*%(!&"*"%&(+'#*)")%"*)#!$++*("""%%"&!+"''!**#!"%!$%()*)&")&+#('$$!!*$&*!)$!("%**!#!%!)(!"$%#"&!
@r8291
CGAGACACCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCNGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAG
+
4<9G@.H9$C$@)8'#H+44(=%$'0?#A-D=B!89$.44=$E6@?.=,H3>#C3"8)5B*G=+;#@?=,2*>='B@@4H#;#9,821*&AFB1.F*G5:(:EFH>8HD884$#H>/*F1D=%$;#$CB)46G1<
@r8292
NNGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGGCGG
+
!$--1AF?D&D'3$DG/1F/**;,#6,=>#.&9E:"'5$2+D"@;E.'<)84.(?&25*>$7.9!@)
@r8293
CCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATT
+
6&)5?=G?0116>$!HGA/$A'./F.AF?A5$**>EE#-'#6->)
@r8294
CCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTATCTGAAAGTACTGATGAACGGTGCGGTGATTTA
+
196549,/07$#DF@)<#:B8A-884CG3/,@E.&/ED4*&*F;;!?>A$$&%;;=D$+3D%80,+;A?-,'!21.9:?$>(C<,G@H(6:07AE,5
@r8295
GGAACAATATGAATTACAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGACGTCCCGCCCG
+
@HG,$2DB>)?+:5=+%2A9D>B5%<"56%=,G<.G*;,?82(3<6#F$#G8D+:3#/-?#.5%17HD%''A%$C)5H+>#
@r8296
GTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGNCACGTTTATTGAGCGCTT
+
3!7>044%(:(=:6#8,#37D)'&4<G7,&9?1(29#35?!*>5$72(;"0:D(,=70A6<@%!,F;C#"3/(9-9B.24=7!@438:GFG461F6"G5&E@GE"?D?D:><.<>9@=+=>&2G*
@r8297
GCGGTTTAAGACCGGCTGCACGGCGCTCNATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGTTTTGCGCACTCTTTCTCGTAGGTAC
+
;37H1F/7.3,.<6A0-!09.D@-)1BFF$G/D=*HF#@44/-F#@'9HC"$:'$>AC"6=A5/-*/D6(=7!3#"0*'H9?:22C6:&3(45+68((+7=)';>
@r8298
AATATTGGACTCAAGAATGCTGCCAGCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCATTTATTGGTTGTNTGAGAGT
+
"G7?!E7D#-=DG85+%&C.!/HH4D8D0H<-".?>=/+D/&)FB*49(*%3**-*>).>4+;4D>G6"%,/G8;&7'?CC9G#=H')7F5G:@+
@r8299
AGAAGNTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTTGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCGTTACCCCATTGATGTG
+
$%"%%"''+'())*&(($&&)!"+#!!(#%(#%)*)%*')#'#)+#)!"!!!()$$!(#((('+"#+!*##***#(%#%(($%+%%)"""%'"'"%)*&!)#*%*%$!&+&'*'+)$)+)+(!$*%)'*)
@r8300
TCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAAC
+
'2G7:A&0,G==FH(!@FHF+GH8&2D?GE8:-#*%F:$*:A'H
@r8301
CCATATTTGAAAAGTTTNCATCACTACTTAGTTTTTTGATAGCTTCAAGCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATGCTGAAATGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTATTGCTGGCAGCATTCTTGAGTCCAATATA
+
/)&2G(*G7+#79B5'BBE%E5GH2E98&H0:118:0H&7D5;"(B8A;<&95)G>*F)$:<78A$+>3-A<'*%"?6$@?H0G.=;#A#,5'106F1*-AE-9$G$+4/3>'>2G!-)E<,352%+>%;.&'C5;D0?=4G$3"@9/B=,=2"5"5B$8833.4-
@r8302
CTGGCATTTNTGTCGCGCTGGGCTTTGTAGGAAATGGCGTTATCACGGTAATGATTAACAGCCCATGACAGGCAGACGATGATGCAGATAACCAGAGCGNAGATAATCGCGGTGACTCT
+
-5((?+6:-BA=C>G-9C3(D"8+00:-$">!?G..&H-7498#8$0.3E9#H?8CHA!(./!-7*!G&H$D>9*:H"H+*44,"A$,7-,,G#@?59$*+$<H7!>4230;4"F2;+F
@r8303
GGATACCTTGATTCTGGATACGTCTGAACTGGTCACGGTCGTGGCACTGGTGAAGCTGCATACTGATG
+
D-8*.4F8?4&B*(2#?.;?(7%2--BE&DE=7&?'.H!(.%?(H;-(,!#@!,7$=)+/4@'&BB5G
@r8304
TCTGAAAATAGCCCGGCGNCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTATGTGGTTTCCGT
+
@A,7H7&'?<635-0G1.071H0B>!BECA$:!(#@,!&=5>!6:%9,CC;,E:4C=0G;9%7%2-G*=/@$HF(-1=5,5;C&04:+*&#5$+2F/%@%1#>&("$C8CAH9="@4G,5"94#*<0B'/0"68=70H?@,%)D+1H0&9."@;!@,=1>->G+-9
@r8305
TAGTCATAAAACTCTCCATTTTGATAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACTGCTTAACTGTCAATGTAATACAAGTTGTTTGATCTTTGCAATGA
+
'&CG&))=*:$)E<G:+60=("94=0/CG/;%':??--'C;B"78A5E-A>8BH-G)66>2@"6"9!1.F).<#.;A2D=,@+%92>B.)$<7(C;B><:0<C*-@=?E<;00$,<1
@r8306
GTCGCCTTCGTGGNTGCCGTTGACGCACTCCNCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGC
+
5813F6:>+-/AG1D6-16*))6.87F,H"G4"21%G$8!78855<"%730(B?C8!1B,H:%F8=7H
@r8307
CGATGATGCATATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTG
+
H="4/!%!(14E-7;8C/?<+&%?F;*7G/8>,8&#&>@2+C)7#=(%5CBA#D-''<B37(&#
@r8308
CTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGNAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTTCNCGGNAACGGCGGCAGAAAATTCTGCCAGGGCGGCAAAAACGT
+
?-+C3H"+A5$29$?D+897<5?+7?7.15D8#26D"!@3?H9)7(;,%19&64'9B9-+?1>04)<%E#:B01/59<.'#0@);&H>=/3-,4,>:/#3<B@)A:)56?:6675#F%1D085H<#"D$?+E%9="%EB7>%1?.C!83G!<F$#)3!&@'.,6
@r8309
NTGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCG
+
'%"9).;+:6!+@F//?GE4*#@",B?<;?&,@EDF)2*?"F.,B+&"%A:7E66C
@r8310
TCTACGATATCAGACCACTTCATTTCGCNTAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCATTGCAAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCT
+
=51751%0;F);>.34FF67,0.4?:;764G:4E<G(19/#1*'*D!+"F,(8;D*G4&,%C,5"?40?4==B:8/27"9G$<7)5(A511-'0&F=79>?1'=..05A22;5H4H0);-@>(G/D=*-'.8G1C(-%,93;4C.-H<4FA>
@r8311
NNCTCGTGAAAGGTAGGCGGATNCCCTTCGAAGGAAAGACCT
+
%!&+)'*$%$#'*)%#($%*)(**#*#$)&'*!'(%))')!"
@r8312
TNNGGNNNCGGNGGTGNTGGGCAACCTGCCGCCGCGCCCGTTTAATATCCGGATGCGCAGGATGACGCCGGACAGCA
+
*!#**&!&#)%##'%(+$**#+*$)'$""#(+"(!+"#")(&$'$!&*#+**+#!)$+)+#(&(*)!$#(*%)*"%'
@r8313
AGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTAT
+
3-A2D0AB!:2=/#.E194$;C2-="51H'F<A=9?4"E&
@r8314
NATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATT
+
!71'$&:A;&8F!)#7%G@6BG!>2BFA%/ECCG0)/;EC':0&8/-*=9D6#D:45<9=B/$+?+#'9H?*<>D&H7A-D@>%-'?001&$!;%8
@r8315
TGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGANAACTGAAGCTGGCGANCGCGGCAATTACTGAAATGCAGATGCGTCAGCGTGATGT
+
'$+)%&#$"%!*((!')*'"'(&"%'&"&###*')''%%'$)(++%#!!'%%(+()+'*&*#&$)#&"$#("))*$##*'+"+*$(("!%$+"*)(')!%%$%&("''$($&)!*)%*%(*%++*(%!!"'"+&'$&+*"$"*)#!+$#"(&$!&"%*&#&%#*)#(!*+'+(#%$)'#$*)$++*$)#+%%$%()!$)!(#"'%%*!$"+%!$)&'#"$('%*$+$
@r8316
CTTCTCNGGCATAAGTCGGACACCATGGCATCACAGTATCGTGATG
+
8F6:1%9+H0(5'94FG59*#,,A,!9))(.FEB.#"60@*0*D:%
@r8317
CTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTNGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGNTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGT
+
1312(CF6>B8A)#G702(:&A.'*)(D+.%-',CA<5#0=')!(:>@<:0HAC6;3'/0.9#B87-'17')D.H(AA$)9!@&C%*28F,9*,C5!@67FF$45FD=5*"!F26G'4#2*(B?6+>.<C819<CE;EC"E-DBB@/%G%C13:20!>#.!8*BF:<?6DF;(H+F1:C,+/?G"F,->E.>
@r8318
CACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGA
+
-HG0"-D7H,7@C!('A+#.<EF-"232$.:#G7$&+3.,C8?*@5C!?6:;=
@r8319
CNTTGACGTTGAGCGAAAACGCACGTTTACCATGATGATTCGGGAAGGTGTGGCNATGCACGC
+
(+#&)#(+$&++$*&")*%($"++"'&!!')("!$*)$&&)($*)#(#'*+&$*!)+*$$)$&
@r8320
CNGNGANNCNAANAACTCGATGCNNNANGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATNTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCA
+
"%)#')#!$&*'"'"*(*%"*$'!#!!%+'%"("($#)!+*&!!#*)"+('(%)('$#$""+'$)$'++*%%")+++('()%$)!%*$#'#%*+"&&+)'(
@r8321
CCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATTAGCCTGCGGGCAAAAGATGAGGCCGGAGNT
+
(,2@><$6B*+#B3.$<+9G<%B68G<=3?G(E&50/6B77A;#3=.1!*7E8DC$:FD5>5/G0>6@G3$D-&
@r8322
NNNGCNNNGNGCACNTNGNGGCGANTCAGGATNCCNNAGANCTGNNNATTGCAACGAAGGAAGAAACGTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTGATACATCAACTGCACCTNATATTGAGTGGCCTGCTGTCCCT
+
(!(*)!$#!$&#)%($'%()&(("#$#(%!#$&*%*!$*)!*(%)&$$+((!!"&$+)!+*+"+)"*$"*%$$%&%+$"#'"**#&(!$"#!&('"!%'"'))))%*%&&*"&$(()**'*+'+)!%"+!++&!*"&$*()("*')"&"(!%+%(("&
@r8323
GCCAGAGCACATCCTCAAAACGGAACGTGCCGGACTTGTAGAACGTCAGC
+
A6)<"1.DD2A8'74H>1+C&E#0H.=?D*2,.#%!3F!8:A":@/)!!-
@r8324
TTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGATACCTGTTANCAATATTTAATAGCNTGAAA
+
37-2:(;=@F;./A$+1)+G."'10A,80)FE&,'B0(,:30G+5?4%2D(=E4*&3%H?$2+8AG7B$$>H!0?&G?
@r8325
GAAAGGAAGCCGCCAAAGTTGCCGACGTTATTGCGGAACTTACAACCGCTCAGGCNTTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTGTAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATCCGTTTCCGTCGGCGTGGANAGTACAAAGGAGGCACTCACCGCGCTCAGTTCGCTGCACTGCTCACTGCGCCAGCGGCTG
+
7'B263>@H&<>E(A5+&>F.H,#G9"5B%("..;%#<9*='>'0+2<60D26"#6<6#@99A=</1@6F"A)53,F0DF$AGG#=?61=(35F,/*6A,;08>)2B:9:-:;%5C(?)F)6?;;@;@+4@(3#;3DC+F<7D#!;4EBE7&A%"!%;:77H1*5)'+:,H,A0-!?6#(%H/!+>E'/:&;GAE5B72+CB)#:>6>$7<(1(!@=.C6*"-,2:@D.-,?A1$:.C$7?D=22'B(@@>4%2%?5A#47H(G7&/28.*>72#"D407!&
@r8326
CAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGTTTGCCGGGTCAATAAATGCNATTCGATTGGCGGCAACCAGAAACTGGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTNGGTCTGCTCAATTTTGACAGCCCACATGGCATTCCACTCATCACTGGCATCCTTCCACTCTTTCGAAAACTCCTCCAGTCTGCTGGCGTTATCCTCCGTCAG
+
@+$%31F$6%=8(::+*DGE=F6;D'+=B%<>F=F;1#E9.-?'5:4):;B(7.482*$0B#&A+4H'?.-$;&>26"0;@B-%C&/%E4H,,6(<0%$'#D3--G>2%&%8@5>@868>=+@8%7A9-:;$<H2.//'4<"H!-G+G-?1>G(&E:!=F!:02G95?1)+<B>)76<C@278(1!@,):,87@>66B%'A$)(,#B2?6E'C!48#0/B767;;/?*0E.3+"#5:!6-9:D/3937<H<F-#(?5)8#&A)5G;$7;H#=#812,;BDF31F@
@r8327
NNACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGT
+
"!&D-315(2@6EH+<#'<&G#1681=1.F;:G@G,=+>=77B55)HF1<%<62'0*
@r8328
AACGGACGTTATCCGGAAGATGGCTGTAGGGGTTGCCATCCACCTTATGGCTGCCGCTGTAAATCAGCGTGATTTCCACACCCTGTTTCTCNAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCG
+
#!B>-8!2(!;G#1!;55;3;,F&4?AB)79%>-&8;;,2EC"2HC937"$/"##'DB3("9@-B)>+);F+:.)C'4.:0)<D?+&<;CG;784;:<7+0;A23+CH1F1!"AFDGA6B84-0@1<))6"
@r8329
TTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCA
+
A6+32&#64>@,:30*3;C=4&=G;D$E@FC:8(D5E)/H9C$)A;2D.#9!D*6/%>4!/E
@r8330
TTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCA
+
98-!$)414@0EA.B2(2(@'#,$=2*E&+B>2)E?-B(#$%&-3EE)D#>>%;4+DF&%D5
@r8331
TCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGNAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCANTGCGTGAAGCCACCACCGCCTCCGGCGTGGATAA
+
>B&6)8B/G*AE%6<$0/C2@&?04'9!FHA2""?%E..!//D"3HF9>.8.>%;..;H3",'2.%F%@,E,*&A;)#-8?:1$G"+3B:%C!1?"'G6(&=)E+3-$:)"DA4-#C%/6:(41<D!3C<+(5/===#34.*D0==144#/<<28;G!+.*-'"AHF5*C>)/F.6#&5*BH-F5-(DE6$#!-</%4%2G)66<?6?)".:@H9=;0-G2/;**@A@;-54#/&=B8H$<=&,#2A/"%$"%8"8"C?+$4*87=A
@r8332
TATTTCTGGATATTGTCATAAAACAATTTAGTGAATTTATCATCGTCCACTTGAATCTGTGGTTCATTACGTCTTAACTCTNCATATTTAGAAATGAGGCTGATGAGTTCCATATTTGAAAAGTTTTCATTACT
+
>#A>-='%&9:;A2717?/>HA'-+:.,D6"EAH*F4A(6&#,F-2D9FA'E4(6;E%05+5';#DE#7#D(#!F&.,+#=G,92?A.#CEH55''*D4/.($@@-3(E/,#/('$=H5)88#$-B4&6+G,#<
@r8333
CATGCAATATGCCATTGCAGGGTGGCCTGTTGCTGGCTGCCCTTCCGAATCTTTACTTGAANGAATCACCCGTAAATTACGTGACGGATGGAAACGCCTTATCGCCATACTTAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTNTCCAGACTAAATTCACTATCGACACTTTTATTGGCGATG
+
AD>1>D$1"2;2C+;-(E/08CHB@<"/FB)>*=2*7#B-)0$><C68-79#,-H.%A*1"/=/7,4F4H=.3,0'6G95?D!@*$H3838'8*D0>F>+5AB()7-.8)E%.5@$>B3(*D<A/"C&=9!=B&'A((A,H>/+B3"8*C9G;>;3=>E)#G%5)7-0(/C3:E=-"0G*BF#43>*;3A"*HA!
@r8334
GCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCA
+
7!:AF+$,0&673.F=E6'(%G79.@C7>)8&>-:2"CDC.*+8>(C!=-B%8,.&=87.(*H4D-BG06:-(*'F"0=0
@r8335
AGCGACATGGTTTGNTGTTATATGGCCTTCAGCTATTGCCTCTCGGAATGCATCGCTN
+
@C;9C;<9("9FE;.++'E973GDF0"110D6?1:!-4%B0"+%7119:%95G?!>,F
@r8336
AGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAG
+
.-A<7=5*4A7$8/,/4EAA7#@9G17B16$F,=$<&H0%92(A9,?CB%>'--7,*:B-!@"%15DA!/)42B7+'7E;H&B5$1((-.1=#C(A2DE/;.
@r8337
CCGTNGATGNCTGTCAGNGCNNNTNGNNGCNNNTNGCNTNCGNGGGCNTCNAGACATNGTNCGNTCNCGANANNNNGN
+
$$#"!$!"$###$!$##!!#!"###""""!$"!#$######$#$##$"$$!!!!!!""!!$#$#!#"!!##$!!"$""
@r8338
CTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAA
+
>:C")4,FDC9.3+205@<";-(2$(<BBGB?!E-'G$F<C<H(($2?/$*0>C#9$A>1"90
@r8339
ATGCGAACTCCGGGACTCTCAGTAATGTGACGATAGCTGAAAACTGTACGATAAACGGTACGCTGAGGGCAAAAATCGTCGGGGACATTGTAAAGTCGGCGAGC
+
+*6H#"$*),22(,8D#+#B6);1E'"#&G//@";$G&HE.0<E>%(HD6"3;C*G'-48&+F47F#>5;)&84984>G,F&A-'2,+174(00<<'%#8(B:$
@r8340
CTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAGCATCCGTTACCGACGAACTGCCAAACGTCAGCGAGCTGNTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGANATCAAACGCGCACTACT
+
5-4)*>4FHBED'98B#,9-:G,#532-B5*'2B<?5$:B"6?59:D"&=$:D;4"5%*">?!><7+D:8?'!02";A<1)3)CH622D>":4,;=4*"E/EF,;D@4F@2D64#9&):'E>E36CD)3>):E=(>HF'#82.0&H5."50"1.$%'-+)!$H
@r8341
GCCAATCGAGCCATGTCGTCGTCCACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCNATTTTGTTAAGCAACGCACTCTCGA
+
?0E:42C2=?4H72B/0;$H;0<@*%91!-9:&,51#%)&<1)FH1=:,81.+A!-9$C5DC"1*2&'(BF=,1(C,%?C@60E?6(@A(#0D3=8D/,H*08/%D*::>%E,C0G$?&,)8B01)"9<;(8+<5"7-D5<A/:21*/;$:($(E6<H52C1*B88,189),88B
@r8342
AGGATTATTCCCTGGTGGTTGACTGATCACCATAACTGCTAATCATTCAAACTATTTAGTCTGTGACAGAGCCAACACGCAGTCTGTCACTGTCAGGAAAGTGGTAAAACTGCAACTCAATTACTGCAATGCCCTCGTAATTAAGTGAATTTACAATATCGTCCTGTTCGGAGGGAAGAACGCGG
+
;$9"5"D(($G=C837#/%)B3A'&2(87>,58<8H7/&&:,!E2/@8*5+024)@"%$(CG@.C,0D$CA<%A@;)C#C)#&49(>2%#D6#!);5!D090D%8!@<B2E@E#?*(7+F!6-97;3'C(99:2&)A!,.B,(D'?C3024A+FE4H315/9-1"(-B,).".47?@-&=78D04
@r8343
GTAATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTCTTCCTGCAGGCTCGCCA
+
B5;71!<=$C2!14,A;C'B43-,D@&B7E.BC4;,8*="4">;/*H4F#(9D?!"2&:
@r8344
ANNNCGATATCGCGGATGAANCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCT
+
(!"!&+)%*'))#$+#+&)*(*&%$!++#%+)'"%*+$'#!$"((&*($)!+!+)'*!#"++((*(+'!)
@r8345
TCGTATCCAGTTTGTTCATCAGGTTCGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAAC
+
B,-;+&+E',?#/-B6?C;BBF&?,=D"0,11$&9./9GA?@E49H<6*=A>4>A)".=4/#%"8,@@E.'/7*C5-B20*&5*=FC!13:H<@0987B:HA?'B@@5-B0(:9CH64.<>81G<%"-
@r8346
TAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAAT
+
#.(8'>*"B%1,7!8D!4(1'6HD5.-(>;F1G+GE?5G?57
@r8347
TCATANNGCNATNNGTNNNNNGGNTCNNNNNNTNTAAGNGAANNNNNCNCCTNANTNCNNNCCGNNNNCNNNNTGCNCCGNGTNGGNCNTANNANCNNNNATNNGTTGTNNCNNCNTCCNGGATA
+
!#!$#!""$"!#"!!#!!#!!$#"##"$!""!"!"!"#!""$!$"!###""#"$"!$$!"$$$""#!$$#!#!$#!"!"$$$$##""$#$$#!#$#"$"!!##$#"$$#!#$"#$!$$#"#!#!!
@r8348
ACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCANCTGNCTCAGCACGCGCCGNCAGCACATCCGCCGGACAGGCTGCAACGTCAGCTCAGGAAGCGTCCTCCGGCGCAGAAGCTGCATCAGCAAAGGCCACTGAAGCGGAAAAA
+
;AF=HC)*5,C.$7'A%@8&6(=8%H>HF+F>='7-75(1%/;&/.@G$;E)-B8##D)'DE5%*H6AC'4H83@37D(3!H43)F8'F:C=>?*##E%#%A':E%E)#%B?#(!!B"DF$59$&G4E/-A0/6>&CC:HE.9%/@!G9)&HAF"@6<,/65";"-2("E/8FD1FF3<=.051@37
@r8349
CATGAAATCCCGGGCGNTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTACGCATACTTTCGTCGCGATAGATGATCGGGNATTCAGTAACATTCACGCCGGAAGTGAATTCAAACAGGGTTCTGGCGTCGTTCTCGTACTGTTTTCCACAGG
+
E5<DE#?4AA*2BE?E,.C"3BBA&86'/,@H&=C$3/1&?91$B-:10D#3C4..G-0C.88'D==<24C:9A<?";?8!=-H4C.,F!487$&=6("FH.$#,,..$42;5)AD$2+F/:/2!G/,11:G3)6$A?(!,:?D&F-(7,&;("5H=,75)'9=5D=7D:"(*6BB:G:3!<6/$
@r8350
AAGATGATGGCTANACCAGCGCGAAGACGATGTAAAAACGATGAATGCCGGGAATGGTTTCACCCTGCATTCGCTAATCAGTGGTGGT
+
4(2C2,#D7>B/,+"!4$)04=GGH4-/4FBE)2,2A43;,-HH(BH3F:/,C6$5##E,.,-;5&&0?'0"2@H*DG?&-'+BA/7D
@r8351
TNNGACNTTNAGAGNATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTT
+
&!&(*$&%*"!(#(%*"+()(!($*+!"(*$*+'%"%&"%')%+$!#%&"*+#(&'"+'"
@r8352
GTATTGTCTGAAGTTGTTTTTACGTTGAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGACGTGGTTTGATGGCCTCCACGCACGTTGTGATATGAAGATGATAATCATTATCACTTTACGGGTCCTTTCCGGTGATCCGACAGGTTACCCTTCCAGTTGTTT
+
H?32'4,0'C&3;-EH2G)&H*60+:6&%%6E*&H:>:%-A=2:*@?:,).;:>,2$B$C6%+/,/CB$H@3*$?*%,7H.!2?>7$=:7D7D=G/1$$<%&>#%?63G34<D5"2'*,<@0390F33!5B(H;?":99+FD-41(+2F06B9,G6)H85>+A'H6<,B$1<G>66(,GD@
@r8353
TTTGTCTTCTTGCGCTAATTTTTTGTCNTCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGNCCTGCATAACCAGTAANAAGATAGCAGTGATGNCAAACGACGAAGCTGACTTCTTTTCTTTCACNACTTCCCCACACCCAGCATGCATACCTTTCCGCCATAACTGTAGTGAATGTNTGTTATGAGCGAGGAGCGGAAGTTGACACTTATGAAAA
+
*+"'(%+%#)"!$%&)"+&*#&&((*"##*%!&)$#+*++!!(%$$'%%++"*+&&))"(%#%*"*!$*#%!##)%("+%%%(+$%%)#%''*%")'+%+'#*!((')'+!%*'+'%!$&%)%$'#&"$*%#*+*)'&%+$+!!%&'++%+('%'#")#'"#+'#)&)"+!#"#!'(+&##)$+%*((!'$*&$&##($)!$*&#''&*&*""!%%**!*$'))"!"$+$%##+!+#*$$**!#&!)!)(((#&*'#
@r8354
GCGAGGGTGATCGGAGTAATCAGTANATAGCTCTNCGCCTACAATGACGTCATAACCATAATTTCTGGTTTTCTGACGTCCGTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATT
+
5B(8:31*#+6-&@/E+400:'0H/EC)#</<#0"1A<BB(*<;A"!7)4E1>500;"8+/?;)"56!'&@9@=F;D"4C"!!"%=@;!4EHF;*D%50<(&7)-GD?G0FA<C;9<!<)B4E-3/+:93(E?(DF)=
@r8355
CTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAAGAGCCCCGCCAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTNTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCTCACTGCCGGTCAGCATCG
+
6""@%>*F='="-3/1'C;+!%H''"8(4!$"45/,5C#G6229';1<F9D7,*$9@F'?%/>+:0B@0GD/),$*,HB1??=&.D%)'>F+#0)!8:$91E55E!>BAFC6C.(C44&)0HB<%.':);AB5A>5>H4.'<E78A3=H>5FH(,(&A942)D--)77!9?)-3-#7:;%";=H?D?6;@#-$%,+<-G:80,/A9$
@r8356
GGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACNGTGCGTGAAC
+
/"63A,@G-/>?:/C'3%=:06!7430==@!#F0.?+%1GA9#:HF??
@r8357
NACATCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCNGNCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATAC
+
!()#%+#%+'(#$!()#!")($*(+*"(&&++"!'(%*'!"#&(&+)*'&$%+!+#$#%!(*%*$!$(##()$+"(%"'*!'"%%#!+*("*%"!&!&**')$*!&("#!+$"!)'&%*%*!+*#
@r8358
CGGCTGCGCTGATCNCACCTCATTTTCATGTCCGGTCAGCAC
+
3#B,+8*56"!==0>#$@6D#;9%+E7)!$9;9=69/<&.G4
@r8359
NNTTTTTTGATAGCTTCAANCCAGAGTTGTCTTTTTCTATCTACTCTCATACAACCAATAAATG
+
$!-#452%-4%;!1*872#5.=:02C5<"3"AC'?5E/:.E6;?0F6H@&6EC-8#42--.>3$
@r8360
GTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGAATAGTCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACA
+
0!9&2#.+:58=*5)@<*'-.FC812;)2G(9,:;:+EH"+-$:E%%??-H=2)+EF5<#@+#!+,E#=->A4(<@-3B(:56>006,93.G0?79-'*8.E9/,&B$,5F-%)D2/5'/'%"&027#A>!8?"H4+4),'$.*84C1-,?D@H/C5@)E))9&*$)63($86((&;>*?G05?B?#B/$2@B0B?:A2*;62G#)7=2C*19?%0&/CG1D:"@().<C0<7@$0GC;H?2EH.:"@>*BDG'&&?8"#>.770
@r8361
ACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGGATCTTCATC
+
E<<%)@>B.'A"<(C"5;2$DD;8>*9%(C<CG!,7GB?*-%5&;
@r8362
TNTNCTNGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGGAGGCGA
+
##&!!&"'+&")))%%*!$+$)"&&*)&*&*+$+++%"*"*%('+$#'%%&(#%()'!&
@r8363
TTTTTTGTTTGTTGAAGGCGACACCATTGGTTTTGCCAGAACTGTTTTCGGGCCGANCACATCCGATCTGACAGATTTTTTAATCGNGAAAGGAATGTCATTAAGCAG
+
EEE@":3F?1$8%'G83?"+65D+502D55-;<=B1#4B=CFB0+%6G>C'!9-=&$$G+C+#@)9B%502%FH.@!0:3).85B,E->0@.?;?&>H28F3,B:!!-
@r8364
CAGCTACGGTGTGTTCAGCCAGTTACTGGCAACTTTNCCGGCGANCCTGG
+
$&!##+!(')$(&()%*"!$&*#)&%(%*$%*(!$(('"$#"''+&(&#)
@r8365
TTNTCCGCCTGCTGCGCCAGCGCGTTCAGGCGCTCCNGATACGTAACCTTGTCGCCAAGTGCAGCCAGCTGGCGTTTGTACT
+
D8#ED-6#*AAB2GD#"*G>4?$##@/D5H2540;*#&11'%7@C%#E-#66!.04:)<"0%$!B'%GB*?(0=('1'2H@5
@r8366
GCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTTACCGCCCGGACTGTCAG
+
B.E=&=&('2$D.G*8E;<8GH68@9#;+F1434:F;$FBH.2!#%G5C31(/E@!=&8.21?&1'%4)F?F3(D!H*H>80"=&2%>DHF@D0,-3D7875,;B8H0CC&.F;=EF;(E+8A'C%"G42-C/2*F-$%11A9?@5!5:&4F8B%=51#$)6F232H&%>(3=D2=1$H1;D0DH-(/,#:#H,=4=39*,0(?&*%-12'?F*C%C<>B;0B32?:ED.(,'GF(8HD=8:C%*B>C(0;->&
@r8367
NGAACACTGCCCTTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAG
+
$";;%&=)$898!@6550G%15H?C33.@80,(&>157777=5'209/A5;!&-&>-6E(
@r8368
CACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCGGGGCTGACAGTTCAGAAAGCGTGACNGTCACA
+
E=0'03BEEC7*%G-&7"5&**182*H#$G.%A*26F<#D!1>$"1414'0A?#>D"-*-1<3($27->35H7)9<AD&./?H3H$,(-%'!DG37*C*-7B54$910-G/<-=+5(!$C2*4*E69@"E"")7.EFD6H+C=5!/"0A)&!7!!57:5
@r8369
CTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCGTATCTTCAACAAGCTCTGTCGCCGTCTCCCAGCCGTTGTTCGAGGGTCAATNCAGTTCACCNCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCT
+
FDGD+3+H6C7-G:;(#?98>#%02&4.*75C2/HFHH-+"CB7C)/E&1,/:C.B(*/?;G754BCD(#2'AB5C5/"'8AB/6CC:9#05#$"1D/)%%A6E2?=F(/,%21D5)=A%D:7,0?,E.6?A.(44/1%+)*57AF:/.?8%35'(<35(!&=($57G-"/4<C&B-9G-"%E8?H<#.!>?A#/.&=(3D*'<:">.H8')&#"&9;H;?@G-,03+-4C01-C?
@r8370
NCCTGGGGACGCATAATAGCTTNTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAG
+
"*8:&)2)>2+7#66*AH;<46,GH)63@4*'C!6'69.%E<8'*!1;(!&4&,#G>%1"FD7";E4+%B?,<0G&5
@r8371
GANTATGATNGCCGCTGCCAGAAAAATGCATTCCGTGGTCGTCATACCTGGTTTC
+
%'"*$%*%($$&(++)(%'&#"$!&)&(*&"(+(&!%&+'$(()*$&!'&!#$#+
@r8372
NNGATNTCATTAAGTTCCGGNTCGGTGGTTTCGAGGCCATAAAGTCAG
+
"%$#!+%&!!&*(($)#%)("!&(("!"&#(%"++"%$'&'$!"#(#(
@r8373
GATCCTCTTCAAAAGGCNACCTGTTACTGGTCGATTTAAGTCAACCTTTACCGCTGATTCGT
+
%<$H1C=63@B?>,.&<@:2=%-G6/'7/,/E1*C4%7,,'-#<&A5#45F>*8<>17"D*8
@r8374
CCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATA
+
5'""?72A*EG!$.D<#H-74$1G>A*8B=B-@;<<;"7C98.&8G/62.?D-
@r8375
AATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGANCGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACACCGCTTTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGGTGAATGAACTGGCAGCAGCGCTCGGGAATGATCCAGATTTTGCTACCNCCATGACTAACGCGCNTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGG
+
(F:""*+BF(&4A;0,!</GB%A,):1$E"',!("HE<B+='?'*/GHE2-633(</%>'D4#<'E<"C&!87H*G3H"<!FA=/BA5%<CA'G8'-2<6712;")CH%<#=)#036%(=@3HG,G;!!D->D:53$%+#8050A;&7F)?D)(B"?<%3C)$.:-E.@(EB/9@756.1FDAGF0%BD?E=2,,G!2;*G1'#92:#1'+;(5?:2+3""0B#;/G@4@E:-4ABG=4&A>15;9/1%F<A.E15C;5"8#!1/=608/$<>;5"(*@
@r8376
TTNNNTNTCATAATTGTTATACCAAATGTCATATCCTATAATCTGGTTTTTGTTTTTTTGAATAATAAATGTTACTGTTC
+
'(!"!%&"(%(##(++"%'&!")$'$)$'')!$#""#!(*""%#'+"$("#)'%$)&%"("%('""(#++$$$)"'%+!(
@r8377
TTTCATAAGAAAGCTCTGAATCAACGGACTGCGANAATAAGTGGTGGTATCCAGAATTTGTCACTTCAAGTAAAAACAC
+
F.@+*732E/@-4/@@E#"?>*E@2?&857HCD?.;47A2>$)G&&=&@#7()010"1#GH%%',"*D55&-0/$D9"2
@r8378
NNNNAATNACTCANTNANNNAANNNNNNNTNNNGANNNANNNNATTANCNTNTGTTNAGANNTTCTTNCA
+
!!!#"#"""!$$""$###!!""#""""#$##!$$#$"!#"!"!#$$"!###!!"""!$##$"$####"#$
@r8379
CAGAAACCCCCGGTATGACCGTGAAAACGGCCCGCCGCATTCTGGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGCANGGGGCACCGGCACCGCT
+
%-%E;GCH%6&-5DA<"$%G*.(G8/$?H16<!)C);+!>,+A=55#FE03F(++41G$G'%$B8A&<*EDG8-,D'?A'/B1$D91A09?&*C.;,E$1,5,D'/E(:?G$H4,1661D/
@r8380
TGAATGAACGAGGCGCGCCCGCCGGGTAACTCACGGGGTATCCANGTCCATTTCTGCGGCATCCAGC
+
*=C%:&,GE=1=0,$&%H/D-48"G:(E;#D!&*@;/G:/#/0=8:*8)3@3C@A#A;G)><,:1?9
@r8381
ACCGGTAGTTAACCAGCCAGCCGCCGCACGTTCCTGCATACGACGTGTCTGCG
+
($$#(!&))'!"+!*$)*#"%)&"&#(*)(+&&*$(*"(*%!!*!*#*#'&)'
@r8382
GAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGCTGCCTCTCACTTTTGGCGTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCTATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCATCATCAAAAGCNGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTCCCGCCCAGGCACCAGA
+
:A"$(*>3B9+C:+'A499+:&)!D"3@D&".<0$H&>A-#3683%A1CF)(<0%D.76B-<>#1.-!($;,EB!3EA!14''978"(9,4A3,.3=(,1>.+:2;C54(@'C<6F99@8$"77#)3;).0$-($*>)3@@$$!)'&4C*E'1%-*(-/)<*27&4-;G000&=HE!A((EC.*(AA':!7E=1"*+FE%E'9BAFA),?'(8$'"=82#*AA0;;=B!'/@FG+B<6%7'86
@r8383
TNAAACCGGTCCGGCCATCACGCTCACATAACGTCCACGCTGGCTCT
+
&!F3FH#7?HB)9+-*.',?7#B)""@C#/3&4=)!4HD*4.$C/>=
@r8384
TCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACA
+
@/-<9@%5-D%-:>&*&,?.7>;F.A4B(@,$1HE<FH$5$?6=H-
@r8385
AACCAAGATAGCACTCGAGCGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAA
+
HF=;D912)C9D#F+B.%'58&G:*+0$G7C4/!F%9A&2BA?14/;/F=#?E<<?G@6<D2"!>!$!;F'02=B39G2(:)B)E3H+:!D@D
@r8386
TGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTCTCAG
+
G=7H-7C=:5((/G>-?A!F>%C-51F42/%$%=',<"3$D::%!B>+7;.4>8*#6D2&.83@+G$)!"5:-1?8.+<+6H6*";'#((,G!$4C+<$
@r8387
TAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCA
+
H-G;BF2$#:+7H"$H',3/+6(A)((--8(&0BDD(:3+!D07@0&%)->)D,<!-A@?)B%"03C
@r8388
CTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTA
+
)8>8C:G&B*099&?%:0%&.)H=D6F)2(H!6'.;.2&,"&C.)&(9H8$"(AB3/A1$;E4%$C
@r8389
CCGGTTTTATGTCNCGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGANTGCCGTCCACCATCGGATCGCTGGCAGC
+
CE$;C1*G@E/"+#<A)A9%G&?)B281,7'G>@D:&B*)E*&6!6A)=!$E/C:>@&76';;#H49$CD32'B2,$1$)!A8';&5-!,4%F>2,?1/"9#<=6G4/1&3522-E>!
@r8390
ATCACCAAATGCGTACAGGCGTCATCGCCGCCCAGCAACAGCACAACCCGAACTGAGCCNTAGCCACTGGCTGTCCTGAATTNATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACNACGTCCTGCCGTTTTGCNCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGG
+
''$++"&(+%%"*"+&"#+"$(&!+"$")'$('%$$&*#+(&)#'#*(&&$++'"'%(+'+++)!$'*)$)&$"*"*&##*!(%#%&!!$)'('$'&'$"&")"%$$)%*##!**!&"(+''$&##$$$($%+"+%%'+#*(!!(((%&+#$!*+(%'(##$()""#&*#")+)%(&))'+$%(#()#)+**&(!+!(#'%$&&&&#%(#+((&(')%'&'"+((!*%!$$(%)*'&!%#"&&()(+%%#$%+#!("%)"$**#&$$+&&"#&%%"+%"+")!#%
@r8391
ATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAAGCCGCATAGCAGAAGGTGGCAGCATGACACCGGAN
+
'5A7H;48.B#:019;)FF@,01#-HD(C5#F(*3:>./$D#5/!/&#3F1*;3)'B@+.<>G15%,A&:?(-'2!D=2E>=<=">&./D/1C
@r8392
NCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGNGCCGCACAGCT
+
+&(&*#!$$!*'())$"##!+(*!'$)*#%*!'%#(%+$($"%$&$#!$"(##%&&+"+'(
@r8393
CAGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATGCCGGTCTGCACTTCCA
+
6=;.8'A#+,'3D.A?,?!3F413>AH@&02=$*(=(0%/E/5<CE@H>-:?<2@F4B.25&D<A,*@A/A$:&@-0/&'#(=+7
@r8394
TCGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCTGATGGACGCAATCTGAGCCTCACCGCTTACCCCCGCCTTAACCAGTGCGCTGAGTGACTCGCTGGTCTGGNTAAACGTCAGCCCTGCCGCCTGCCCGGCACTGGACAGGACCAGCATACGATCTGCCG
+
("+*(!*)((##))*#*&%%%%!%'$"+((!+"!!+$)"*$#(##""*+!+)'&'"&$*$")"#"(&"#!*(#!+++(#)'))'""!$$**%"))%#*!'&(!"'+"'%!+"&%+!%*)&%'+'$%$##)#$$!""''*"(#$+)*$)'&&*$##*&&+'&$!*!$%(#("$*%!!'(
@r8395
NNANCCACAACTCTAATNTTAATACATAATGAATGATAATAATAATATTAAAAATTTCCTGTGTAACTAATTTACTAT
+
#(&"%+*%*%+'!((""&)+'$&#"!)%)"+(%+(!"!"!!*%)#")'()"!!&&*)!*"+&""#!#&%&"!&*&(%&
@r8396
CNTTNNCTNTNGNCGNNAGTATCNACTGNNGAGNGTNANACCNCNANGANTCNTANTTANGNNCNNGGNNCCGTNNNNGNTGCACTANANTANANAATCTCNNAGGGTANGNNTNNNNNNAGGCGNCN
+
#!$#$#"#!"""!$$"!$#$$!"$$"$#""!##!#$##"$$$"$#$$$#!!$"$$#$!#$!!####$""$$"#$!"""#"$$$#$##!$!#$!#"#!$#$"""!!$"""!#!"###"!!!!$$##!#!
@r8397
TGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGGCTGGCTAGCAGAAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACTCAAAACATGACGAAAAACTATATTTCATGCGTTCAGTCTTAAAAGCAATTGGCGGTGATGTAAACACTATGAAC
+
AD4:?$*>4.8>.G4@$;>D.*@.4-$$,CC0+?FE"+6'H>"-49E'17=-E*47"8A?2=1>;F%.09!4+0$/%-<?2GG-+069GAB%3/",8'!&A61H5>9%=FA$'@/54)A'9+7DG*,?9/F'5>807:$>/E$;"'344E=3HF:=B6&F12.>487(3*28<E6*->B=#+G?)30/F+,!)6@4?2.1:$8>.+-3/;&9C>DB*6E4G?!%)E,B;H=@<!D)'G)(84&3BH58/88514)%#?,7F:H,)6*-;*9/.08C53/D??'>&1?D5$)"DB7"FABD%C'&<3D=6/?;H')8F6':#
@r8398
TCATTCTTGCGTAGCAATATGCCATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGGTTAAAAATAATATCCTTGGC
+
;FH10@<8..-,9BD.:+D598;88A?4#?.#*939DD-"7E1F-8&4B($<$"87>6F;<@-"2A'G87*'B#@%EGF-7!9A925)!<B7/-@A<$&6?9'E.E7:$#:74$"<HA=D'51H765+=BB*8B4FE5C55A.=#;'A<#%&,4137GH?!64#+A;67.C2!@AA(:@2H>5F
@r8399
TTCAATTCGAATATTGGTTACGTCTANATGTGCTATCTGNGCCCATATCATCCAGTGGTCGTAGCNGTCGTTGATGTTCTCCGCTTCGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCNTGTGACTCGGAAGTGCATTTATCATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGCAATA
+
$?5:8:5G9/'EH>,**C.(0/D4;,4,,=64#,,$0E'*:@+3A=<";ED=G6HH*90GF@H!DB%0#/@46:>E"061/&"-D/HD98!=1#C((68D6:D.821:%*$C+*AB3D0-92$!$'"C/#(FF+9($BDC(//0"<.0>FC#<!26:=<'B5C=<)+G5++0-;,E#<H@H@F$7F"<%><83$@(,31+6!E+8.1C?/9:FC1%3-2B#B>
@r8400
GGAAGCTGGCTGAACGTGTCGGCATGGATTCTNTCGACCCACAGGAACTGATCACCACT
+
>B/+D),**$:"&9.,#84;E3:36@!*?$*0)$$#4<@=9!$D%8!'7H69,CHE1&%
@r8401
ACAATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCNACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGAT
+
)(;4B'E8C*(=!%@B0C;%&H42-&@5,:0;:-3F=CG3916;9H;*?+"9!)(9<1'1&=$6?B=%?D,/9B?%#=<DE$D(F*<%C*0D2<;848G;@">*(5B4#&+%)D5/0>4189&91>/0C)7HD@=(383"C-C%A><5(&B*3D)&';#
@r8402
ACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTNTCGCACGGGCAACATGTGACGCCGACTGCGATATCGCGGATGAAGCAACGCGG
+
D0'+4H$!,(%;.#D'-!,94;=HB,@5/>#6,AE@%&1+$7A(A@"G9!G+(D(<:/!H#E9$&#:=%+"0>"#(!1'>?:-79)A@351"8BB>5;=,46//(";1G71B>9*0.&"!6?C89!',)-+C#$:G<E&:F8#-FE4E4B#:*1<9
@r8403
AGACAANAAANGACCTCTTCATCATTTCAAGCTATTAANTATTGCTAACATGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAAAGAAANTCTT
+
&)*#"&&'&"#&(+(+("&"(*(!'+)&#)!#!)'&#!+%$*#++++#"&)*#!!*%!+"&%'&&+$#'"#'()(''*+$(*!+*$%#+)%&!$)*+"%&'"$!$#(
@r8404
TTATAGCGGTCCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAAGGCAGCAAA
+
(+)''%&#""&"'(#$(%"'*##%+*%+$+('%#++)$!'#)#*"')*+('$))$'((($%'$!!#)!)%((*
@r8405
CCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCNCCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCTCACGGACGCGAAGAACAGGCACGCGTGCTGGCAGAAACCCCCGGTATGACCGNGAAAACGGCCCGCCGCATTCTNGCCGCAGCACCACAGAGTGCACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGANGCAGG
+
++:8*9C%C1>&>41)G3?G@*1F>4#A37=?A'3909+%!"7"A0;0+4::C>/&,C1;E<AC:<0*;)>&%E<A2,0/($%/F3AA:6HBH<*3'$$-:*0HC3?$>%4$)4,;>#@'*/%G!??3B9#*5!&'?F>,#9A/030?*+-9HE/47)D0F*%EE9.D?"7;91=:%<=?!9-F/&%:#C-23)F7E6#(,EB?3<H>+B66G7D=("$C&@*-8*#9/G-365(;"3'/$:;+<=!:F1!84:E.!
@r8406
AAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGNAAAGCTGAGTATTGGTTTATTTGGCGATTATTATCTTCAGGAGAATAATGGAA
+
3,A3A?*-9F1,;65?0.C@(09)3F?B:H1@*E:(<0;)*57A-*&$4H&A7;7<1>=8#!.&,;6>'2.5*;!8-H:B:DB$%-'$>G$162@)
@r8407
NNAGANTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCA
+
%!$%)#+$+"*!+)+)**))!%)'"*)$"%))'+'!)+")!!)#*&&!*%''"+')*%%*)"#('&+&$"$$
@r8408
AATCACCGCACCGTTCATCAGTACTTTCAGATAACACAACGAATACGTTGTCCTGCAGCTGACAGTACGCTTACT
+
;5-0944+.A=>.D5DHC>"-B&!7=*=>(&;&AF9D>*H:6$5H>HHH@/-%@C(!9512C&C+1,=?"(7EEA
@r8409
CGGACACAACNAGAAAGGGGATAGTGCAGCTCAGCAGTGCAA
+
4;!F&=HD<D?(*:!.77.?#=&4$?BAC&5=)@CCE)(!=0
@r8410
AGGAATGTTTTCACTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCNAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCGCT
+
)=H,=)-BG,E.<="62@.?.4.?GC,D<G(4$:$H98B;H7G#@D-$+D.'.%:<)66A5!$(&D2D58@0-@"EC'0&39B,C+=4''1406-;;,B,EG'&5=.H(+-EH!B-1*>/B/B.C5-$5C%#A0<=:/#B3AC%!6
@r8411
GCGTATTAACCAACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTCATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTC
+
;@?=!0#=C%,/H7,)@DH1890/(=CF+D5;:81)956'*!+5!GD312+,6EG0-E.6,"D:%DG''=%9<0/*<);(!"EG!?G.+E5+'=20?3"=!,<4"C04&2B+H<5*+6#@".&?F-@452".D>-<>A8%4$1?#/;8/8>2@D7:D/00@8E!EH&B87''3%!CDEC761@!2
@r8412
GNGCACATCCTGTAATAAGCAGGGCCAGCGCNGTAGCGAGTNGCATTTTTTTCATGGTGTTATTCNCGATGCTTTTTGAAGTTCGCAGAATCGNATGTGTTGANAATTAAACAAACCATAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTT
+
5F3#"C1@*2?"$5!B<%2$B=*<E'!>74'7-#)B"9-:CHA3A"=!!A,*EA@429*G4=&E-D0/)/>E;.C'@&'41$00$4,%?FG3-++'8F"@8BH6)"!!.F%7;40D&6FD#0,',)2!!3G-#.#&<>=0+>E?(H;12>3'758;0H03F@8''@$8#@7G9.'8:)?!'8>?=BE/3,*"F1/3<(1H>,)H.!$?+";78E00%#!6?<?6<7E:?>
@r8413
AAATAATAAATGTTACTGTTCTTGCGGTTTGGAGGANTTGATTCAAATTCAAGCGAAATAATTCAGGGTCAAAATATGTAT
+
#7//@779.5#B9?>8=%3>(:B'>E$6DC-+"G</5GA&D<7%*;..4@6GC;7G"D8F9H,-E<36F3;5C'=*@42=3
@r8414
ATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATA
+
4<+-B*45B:F?($=/&#E')B*'&>B:*;&$$/%D""?(<0/
@r8415
GGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCACCGAGAGAAAACAGGATGCCGGTCATACCACCGGCCCCAATGGCTGCC
+
(6GE2;3E!@B&29%"$5729C/$;*4=@6*D9-0H857"3@A8F%=,1!,&?A5A@%>AF%$D?D257,C397<"C;"61H#B('$<;630089/;
@r8416
TNNNGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCATACCACTGACCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTCCGGCTGGAAGGCCACCGTNAGCGTGGTGCTCTGCCCTTTCACCACNGAGGTGCTGGCAGGCGTCACGGTCATGCCGGTTGCCGCTGTTACCGTGCTGCGATCTTCTGCCATCGAC
+
()#')+*'"*"$'&%!+%*!"+&%+%!"$"%'"'')!#)!$(&*%%('##+*(&%'($#&$&*'+#**+**'''+%%#&++'""+*"(&#%&+"'%+"(%'+%'#(#*(+'+'#"())$(%$+!))$%!#+!*$)#*+&+!""()(**$+"*'$#"&%!*&($$'*$%'+!'%"&#'!&%"#'%!+*)+!&"%#$"'"'"*)!+'+%#%+!!'&#'&(&(+#)(*))*&+
@r8417
NTTTGATAGTCTGGCGTAACCATCATCGNGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAAACGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGANCCCCCATTCAAGAACA
+
#1)E1$C#754+G4H;*9;+H@H95B#5/8,ACABB,F1F',;$/D611?:CF!&)*##@&)@::)421,++A8?9(.FC/,6&0A!F7C9D6=8E5-CB%C-A#&:B-G,H0,>,G/+>09@+%D5%FC->$'4.5:9<=-?;31$*%79<3;"8!48.;68.E2%)-CB!32A85'7D:0-9(/)7#+@1$GC38*5<D)#8"FA#,!B!9C&.HB,F18?!$@;CH8:7915@1+A)F467-*6D@+,.)-=7-%D"0
@r8418
GCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGGCCGTGGCAGTCGCATCCCAAACGGATGTTACGTCATTAAGCC
+
<&7.&%#0>H*#07:92F,H<8<+/9F'"&/$D.F>:1;8:;%DD==*<-=A<&;,,0;C#?.<A183C$B?,3+C+*7'2*17!(
@r8419
ACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGG
+
C=;5$E+/1?:!!?@7=FF-0E(!:9C3H4D)/<7&.,$?51F7@B(=@68*=4&@4
@r8420
GGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCNNATGCCTGGTATCAGGGCAACTC
+
+%'+*)'$"!!'*+$*'*#&$%+(!)+&!("(%!(+&$+"$)%+!!"(!$&$*+"$*(#"
@r8421
NNNNAAGNCNAGGTAANGNNATCTNTANCATANAGATGCNNNNNCNNNNATNANNTNNGNAAACTNTCTTGAGNTTNNAANNGTNATNCGNACNCTNNNNCCNNNNNNGCNNTNAGNNNNANCNCANNTNNN
+
!#$##"!!$"$!"$$!"$#"!"$$#!!$$#"####!"#!"$#$$#"#$!##!#!#!"!$$!"!###!#$$"$!!!"##!"#"!##"$$#$""$"!#"#!$!"!!!!"""!"#$!"$!"$"$!"""$!!#!""
@r8422
AGTGCGCGTTTGATTTCCACGGATAAGACTCCGCATCCGGATACANGCCTCGCCGG
+
,6$2),FC3$H/..!+953@*35#&-%BEH0$D644FH>A63DB-4E#(3-+GC#;
@r8423
ACGCTTATTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACT
+
-3(";8!:4DFA;&?C3#?%!+)@$$)C<83D+4!@!D-'!.+8325B2>.
@r8424
GAATACAATGACGATTCATCGCACCTGACATACATTAATAAATATTAACAATATGAAATTTCANCTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTGCGAACTTCAAAAAGCATCGGGAATAACACCATGAAAAAAATGCTNCTCGCTACTGCGCTGGCCCTGCTTATTACAGGNTGTGCTCAACAGACGTTTACTGTTCAAAACAAACCGGCAGCAGTAGCACCAAAGGAAACCATCACCCTGACATCATT
+
+!&'%+'%""!)"+'"+&*("!"%)!('%#$$%'#)!&''*))%"'%%%&&)(+!#+)""+(!%+"!!&)%"+('%*%$*%(()&)*#*%&*''(+*$+#%'(%('&'+")$'$*'%$*&!*("%$%%*%!"%((*%"*+!+"("(!(*!%*+$*'#($&(+'#"')#(&#)&+"###"(!#%(*&(!#&$'##(*"((!!)++%'$"++*!#*+)''+'$#)&#'&*(!')*!("!#%&)#"&%*(&"'+'$&''!($*&++
@r8425
ACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGA
+
3DE'/"AC3)0?BA/@*?2-7?=EB)'1**%D=A<'C(!6+,'7@F(&==.8>/*>2?D3D@>E)5E'E?%BG:4C+7$
@r8426
GGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTNACGCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATNAGCCTGGTTGACGGAAGTGGCAATCCGGTCAGCGTTGAGGTTCAGTCCNTCACCGTCGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAA
+
&=+'-/DC5$'/;CEB10=*(!G**93E*E%+<2''/8/56$1=1/=*=6.?G)0&<G@BH7AE;=!%<,4,(65>5-<;/("3,DH/,9E,F@G:F878C=<6(D%0D@<E!52B:DC-3&017$AH.*!G#0,7--%H'.,;G"D"!>B#'FCF:?+<?D'!@1H3-:.C#:(',A7&8#)>H68F;4)'H8''=+)/?!36<)$&6<9,.@2?.E.51:9)C'08H,#>)'9$H/='4,+@@&=,/9.FH?C"&!B<H9@'3/)DF4$3-<%,H:11FD8,BEE$G(66("#%!F4;H1$D$G7<5C/>3:,>(&=*7+BF<#F+><)@+'0948"$6
@r8427
CGGACGTTTTTGCCGCCCTGGCAGAANTTTCTGCCGCCGTTGCCGAGGAAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCTGCCTCT
+
4)A5=1H>F!!EC:;%03FC6<"4(9>7H:@7=A3G1$$0&G&C;"3*&/*-A5'=D4%FF2@H,!2&-&8=/+)7$$24A2B@07,:8HB'D6G5F1.,H35G
@r8428
TGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAAT
+
*CFC.6H!.?4/)G)55:<-">7<D;48'A?6@G4DE44G$B)-%=#:E('E-(=G$
@r8429
TCTGCCGTACTCTGTGCCACCACGGACGCGTTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAA
+
B!51-)#/B>((*@/9E1<H#>196*$-$:8G.>)A**-3@H?55@"2?5D.4,#=<1:;D<5/D;#>+:)#'?@92!@4E%#=E$G&?:4?&2G$F-1F$&);*0(.3$9)%
@r8430
CNGCCCGNGNNNNNTTTTCCAANATGCTGCTGGGTGTTTATGCCTACTTTATA
+
)"#&')#"(&'""!)#%#&($)#&+*%++!%+&)+*)!(%**)("&+&*&)"+
@r8431
NCACCCGNGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGANGGCACC
+
#))(+**)*%'!'('&%!'+*%#&#"%'*&)!"%(%&&')&+''#(%"'+&'*&&$#'!"&"*$+#&*%*&&!)$)%"*&"("%&'("'"("#()&
@r8432
CCGCCGGACTGCGTGATGTTATTCTCCTCACTGCGGCCCATATCCACCTCAACCGGATCGAAGGCTTCACCGGTCATGGTGTATTTGCCCTTAAGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGGCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGG
+
)2327>#<$7D7,),:G.2A+12F<%#E58'B3&2EC<>E5-)B?+'4$.@'"!+7#6/=2C<$F.3>-9:(*%>(:HC/E.+$C/-!:A.6+<.?H0'66!5,5')$=@/%!7&7D%$(B61%+%H-2FHH)!*G#2-GB2@6E(3*33C8EH?#C;><+@F!ABB1#+='47"C.::1
@r8433
AGTACCCAATGATCCCATGCAATGAGAGTTGTTCCGTTGTGGGGAAAGTTA
+
B1:B16@F&,7#&?9:@5%*2>=/'1C*DB.(8%1!<FH/<H26H3)6(,E
@r8434
AACTCCACCCTTCGTCCGTCTTTCTGTACTGTTGCCACCCGTTTACCTGT
+
9>4>#>*(>B'0%B358985E(0>!2H.B7?':A-DD761'%B=:(>6=+
@r8435
NGCGNGCNGNTNTNACNCNNATNCNGGGNGTTTCTGCCTGCACGCNTGACTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGNCTGTTTTCT
+
&&)&!))"$%%!()(*"!"!)&')!%)&!+*&$*&%&+'%%)!&#+%&'("#*!+*$!$')"$+)'&%$"(&'"#!('$&"$'%)%&&"!')#")#)%)%%*&'($!)*'
@r8436
GNTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATGGGATCATTTGGTACTGTGGGTTTAGTGGTTGTAAAAACAC
+
!+)*!%#))!*((!&"*'%+&+(#+&#%''"!&)**)"#(*)$#)+$!()*'#'%+*)*(#)$!*(+'((#(#*"""+&"%)#$&&*(
@r8437
GCCAGTCGGCTCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGNCGGAAAAGGAGATAGCAAATGCTTACGNTAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATTCTNTTCCGCATAATTACTC
+
8%0A4%.1CGB.(.&&?4C2(!:-#;EA>!,5,"C'F/+!4"0-76E"1G/.-!#(;-0%(9?D5/DG17*=H:C@4!8/<*=H90?@0&1;)E3@=B:06*C6(&)8&;:F-!E::68=424&.CHA"4B&C:8.?D.6!51=B88E&!A,.<?/#9FF&@%4@2+1ED,'+6C346>/'%65>$?4A'927(7)E45.23>C6$)3H/01@4-3$;C@E%GA#"
@r8438
GAACTCATCAGCCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCAC
+
H8?H19&34?.=27(-G,93:,%<!9:/6A+5%H(=<F-74','-4!.16C@
@r8439
CGCAGAATCTGGCGGACCCGGCTTACCGCCGCCGTCGCATCATCATGCAGAACATGCGTGACGAAGAGCTGGCCATTGCTCAGGTCGAAGAGATGCAGGCAGTTTCTGACGTGCTTAAGGGCAAATACACCATGACCGGTGAAGCCATCGATCCGGTTGAGGTGGATATGTGCCGCAGTGAGGAGAATAACATCACGCAGTCCGGCGGCACGGAGTGGAGCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATNTCATCGTGTTCGATCCGAAAGGCTGGGCGCTGTTCCGTTCCTTCAAAACCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACAGCGGTGAAAGACCTGGGCAAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGAGAGNNCGTGGAAAACCGCGTCTAAAAGAAC
+
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
@r8440
TGACGAAGAGCCTGAAGATGATGTGNTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATAACGGAGG
+
A6+-G'4,>E;6G,664!.'C+8.%>(8/$=)5C4:;A/?%*?"4-"$F>D?-"%5BBD,"5&&F8-3F7538$,84:,@0D'!<704FHH6=51BF>)=):!"EG48&%3);$@?65B##5E),
@r8441
ATTCTGGCAAAAAATTCCGTTGCNGATGTTCTTGAATACCTTGGGGCCGGTGA
+
9E2*D6F5$H9*>?C+?!7''0E7A%*0A*F-:4#=<F;35;37(2A="17C&
@r8442
TATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATG
+
7H3!4(%!H@E0G+?0$EF$=+D$#HD.>),G<&4.'D,*G6$1/CH6$,.@@#3H36
@r8443
GGAATGACTATTCCTTTGTTACANTGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAAAATGCGANATCGGA
+
(HB+2$=BAA6)"4'3@>&%6G3*C@G*-&CF#&9C5;;%>8A*))A!3H%+6,9%/&%.EG6%>F3FC%D1$5
@r8444
TNAGCNANGCCGCCATATTCTGTGCAATACCATCAAAGGTCTGCGTGGCTGCACTTTTTACCTGCGACATACTGTCCGTGGCGCTCTCTNCCCACTCACTCCAGCCGGACTTCAGGCCTGCCATCCA
+
##()*"$"+%#'(#*'"*')%+%+&&))!%$)+%'+"%"$%$%!%+!+#+(%''%)('")+!'&##)$%+"#*'(#"*#$*"+!'#%(('#**)"'%!)$+#"$!*&'%(%$')#!%()(!#$"'%+
@r8445
CNTTATTGGTATGCGGTAAAACCGCACTCAGGTGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCT
+
%$+)&%+*(%$%+#&"+'*)$*''%#)')%!(#!*#)'!(*%+('#&%+"(#$))))'#'*+&!$&)')('++#+&"'%+!%)*&()$('*)(
@r8446
ACACCGGATCTGCACAACATTGATAACGCCCAATCTNTTTGCTCAGACTCTAACTCATTGATACTCATTTA
+
=A645-H;0%7.<<C/"?%$F',8E$05GC**)G)G)EE6CB8DG,>,3F6BF-<B1.=6+"C5;#B6$,9
@r8447
NGCANAANAACTGCGTGGACTTCAGGTTGTCCTNCGCTTCGCGCGGGGTATGCCCCTNACTGCTTCCTTTACCCATTCCTCACGCTCCATAAATGACAA
+
*')!"*$$++%!&%(&&"+$#+&!#)+*+$%!'%'%*!**'+('(((&*'$))%"!*!(#"!$"$+*&!'&)&#$#$*#"$(&%%'&'!("))!$$&(*
@r8448
ATCCTNAATGTTCGGTGATGCCTATTAATTTAGTTCCATCGTGCCGCGACTGCAAT
+
)0>&CA8D9%6-)$!-*0=46#*@"@/."7<#;52$9+;#(D4,-89#6365!/6E
@r8449
TGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGC
+
-@#<88,F*&)1>6C(9EC=4+-,G-F+"C,&/(<#?B7?$%B>8)0"?8HF6"<.6<"B8$2(D%;=$/+,=?;=.B%
@r8450
CCAGACGCGACCCGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGNTCCCCTTATAAACCCACGCAGGGTGGTCCNGTCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAANGACATAAGTCAGATCGGCTGAACTCCACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGCCNCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGA
+
:*9!=!/)))'276C#C2&$"F7/'C5(+H6*G:8A!C@?*#8=G"B$!6C0H$409!A63%$4"3+A,%(BE0G$(G(>76C*D)>!;*E6E;%43/#59225;A5.23-G8G867=&B8>+,?E)'0=$27AH<5,*)=C3C9;%6E%0+,.?#.64(+>B.@:H,-$42?)HB?'E0E,FC.!9C@7AC,39=-'!G)6-H!59/H"CF6(G5/'9?F91=!75/8=.>H)@0'3@<B6A@F7:2G6#,'5%27H-C+H8?7<F6?@0$?10A'%A'8+6951::'?G.B'(.1@@+8.1&.>9@+6?2!(:C@H8<*5@$
@r8451
GCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCT
+
,F''(;61G4;#4#87G9G19:!";+<!9**54E:G$-1?-2(>?&D*5#%'"?G/
@r8452
CGTTTTAATTATTCCCGGACACTGCCGGAGAGAAGTTCCCCGTCNGGGC
+
'F"0AA#4$-561"C:(5(FA$.'1!>08&5>?/?2#4%@D=H5'<#"E
@r8453
CCTTTCGGCATACCATTTTATGACGGCGNCAGNGTCANAAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATG
+
F-G9E)2.4*:B:/>'4:5*B8.=.7(!&E:;.2CB'ACC+=$(@"FC(=)B6:E+D2"3(1G6G8((225196$>79?16F@7B=<3H?4C#<FCD5440.8E#0(@"<:$FA=?23?13G&@362'5-
@r8454
CGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCC
+
.992BH67=)B84.+:47%&#)=6A77,>E6"<<D'@B1D89H,"=6=6@,#-A8"&@#61B>G$2@73DD(+*?%+2AA3.:*@+B$">&,H@@8&*0&4705'2*6?A($#61)A82!-C@#45):*;#64H89',68
@r8455
TTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTA
+
)4='$,*<'<=-,:-E*$(%.90%'9C8'-97(;.GB,,$@?C;
@r8456
GAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCT
+
7&.8'B0:"=,B-*B921E78D.<*8FE%,>07(96H4,-@-$&-
@r8457
ANAANTAGNNCNCCCGGANTCAGTGATTTAACTATACCTTTTGAGGTGACG
+
$$'(#!$'###&'##&!&!'&)(+($(##"!*%("$**%#%)''((%&&'+
@r8458
CTGCTCGTTGAGTTTTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAATATCCTCGTTCTCCTGGT
+
>2?%8(><87>(<F=BCC!,/$0ECA42'4?9>%F1$1:,+HC5,C5*<A#@439,#,'>9#(+-36*#7G-D@G7.:$=?16
@r8459
AGTTCCAAGCATTGCGATTTTGTNAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAATGTGTAAGAGCGGGCTTATTTATGCTGTTGTTTTTTTGTTACTCGG
+
8?!/'/D5G,H7.1C$4E#(9;G;CB")7>1E)5$E$A#;C#.49>6E$<'!'.?.:;0HE1(B7'58"#<%!GC/E77FB3-;)(0""27E'B8A%=7.&'$95>%8.BHA5$8E3"A'")@EC86;(#0/;7706F%A88%%*=5E,3!'$.*'+H-6?%D52>%2(&CF@:&.(F16A=@51(8&<6"*G@!&-.*5(6><)-D:*1F<8DF?-
@r8460
NCNNNAGAGGCNACCNNGGNANNNGNNNNAGAGNNAGNNNNNGN
+
!$!#!$"$$##!"#$##!!$#$!$!"!$"!$"!!!"$$$!"!"#
@r8461
ANGANCGGTGAAGNCGTCNAANCGGNTNTAGTGGATATGGGC
+
"%#&#*&)$*)"''!)$'$&*'*%)$(%)&+('&%*'"+#"+
@r8462
NAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTT
+
).000D>"=H&HHB,FGCC(-.>5#407D3&'9&/<A*A,)8@5$@#F&1+=FD;268A;-5#=<C:<6>CFD8>*>BG"9
@r8463
NNNNTNCCNNNTCTNGNCNNCGGNTTTANGTNCGANGNNNNGANGNNGNTCNGNNNNNAATNNTNCTNTNNNNAGNGCN
+
$!#!$#"#$##"$$$!"$!#"#"!"#$$!!!!"$#!!#$""$!"$"!$$"#!$!!#$$$"#!!$!#$!###"!#$!$$!
@r8464
ACCGGCGCTGCGGCGTAATACGCGGCAATTTCACCAATCCAGCCGGTCAGCC
+
,D(-0:6:"*'1*,3-3(/3D>>)4&G?+.%";4D6C&3.3.$6-FH;*H'/
@r8465
TAAAAACACCTCACGAGTTAAAAGACCTAAGTTCTCACCGAATGTCTCAATATCCTGACGGATAATATTTA
+
'F@A=+>/H2;:4ED!G=/992!5&=%%)(G2>@C#B@AG@8D*">B&:+:2#'A:7>&.6;@@'HE7+?>
@r8466
TTATTNCNNGCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTATCCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAA
+
'(%&)'&*!!'"+%+"#"+"%&"'!+&#("+'!*')!#!)(%"""##()+)!!"***()!"#$+$("(!'(&&!*)*)%'###+)!**'"!+!%*++#'!%+&+&#(%%$(&$!$'**$&)$)("'*!!&$"(#"+'&!&)#**+)$"!!*&(($#*#%(('$%"($)*""'!#!&+!"&""("*'!#&+)###'"''"!
@r8467
CTCCGGCTCCGAGACGGTGCTGGGTACGGAAGTGAANTATGACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGTGTA
+
41:;)=!6:).')BH8B;%4%<(H'F))8%@DB@$A3%+46/>:&64+#'F:A:DB<??<)2D(6-G805FGF4+2+?'++<B&B"!$--:-@/&G(*#-8-D@F4
@r8468
GTANCGCCTGGTTCATTCGTGCCCTTCTCGANTTCGCCGGACTAAGTAGCAATCTCGCTTNTATNANGAGCGTGTTTNTCGGCTACATCGGTACTGACTCGATTG
+
!(#+##'&+'$()#)!+$##*"&*++$'+))$'+$)(+$"#!$&)'$&**!&'"'**#*+"""")&$)+$&!*!%#'+$%#$!)#'%%!!**)#(&*&)&#'"()
@r8469
TCAAATCCATGTGGGATGCGGTGATGGNTATTGGTCGTCNTGATACCGCGCAGGAGATGCTGATTAAGGNAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTT
+
?1979HBB1"?<A,9#6A27%$E'<>,14.6520#$B-1!094#G99EE$58,@B")4@9)F;=::-G;D96++(#"'.!!"4*9"&2&3,A=)H4GA/FH)$*+%4E(;(;!1.A=,@)A26"+;+*51$
@r8470
GGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCATGGTTTCATCGTTAACCGGAGTGATGTCGCGTTCCGGCTGACGTTCTGCAGTGTATGCAGTATTTTCGACAATGCGCTCGGCTTCATCCGTGTCATAGATACCAGCAAATCCGAAGGCCAGACGGGCA
+
G#C1;/2#1-B+DB,6;7==/;>2>?&7?A3#':#,<A6-EH#511<)+"AE>)1@A2C72<8':>GE>:8"A'D:8(%D?A$#1/<F4$'9F7,74=&-<*$E=%2/@C+/%%F=92;6.5-.C-+,<9B>26C&G@'D;8.*+><%9,,3(CB/G<78D(=/B!DHD(%C.$C.7$&.*<E9C1E$@50A#C=D$-FAH3$A=E1+:G0<>:?3&,CA1#$2G8>H(9C9#7G*0#1$CEE*,.9
@r8471
GCNGGANCNACNGACNGCGTTTNANTGGGCGGATGCTNTTTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGTCNCTGGGAANCAC
+
*""%'*#%$'$)$'$!#()!'("&++!%#''+#())'$'!$*!%*''+"+(!%+$'$&))*!(*(%)&%'%(!**+)(++%&"&&!'"%
@r8472
CATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACAAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGNTTNGGTAAGGTTTGGGATCCCTAGCATCGTCAC
+
<7%-?+$+?-:?F&*-)/=GA4F<@2G,)83A(*88@12+D5H69<H6B>/3FC-$8A:3%7#-98.01#9C%2+#%!$.(8$H8?=('35<H5G,B'*;?9D6H3@4.0@'1"CAH%/56-?4-(//-?4#D>'A<9B/C(>(2
@r8473
AATTTTGGCTTAATGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTA
+
><EG.;'&;:"%227.2EG,$1=,A/0;$#4-9A8=H<$BF1(@:F<BBDD*+8)4<=C#&C62"-A)43?),,)"$GA=)7(ED,CC"CBD2&
@r8474
NTTGNGATATNCCGCAGAAACGTTGTATGAAATAACGTTCTGCGGTTAGTAGTATATTGTNAAGCTG
+
%(((#(())&%+*#&"&*&+&(%('+$#*!("*!%$%"!"#(*&#'$'*()(("*)%')%)&%$*''
@r8475
CTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGC
+
0-=>2<%>8A7F!54!)D!%A$-?:F2$2.F84$:0A'-/*0/F0C/!04@9+E
@r8476
GGGNTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAAAGATGAACGTGTCCGCGCCTTTGATTTCTTTCACGATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCNTCAAAGGGATAAT
+
++')''#*#*#$!+)!*"''')#&)'#($'%%('$#"!$$$(+!"++$#%$#!+!!)+%$$)*$$$$%!%'%&&#+#&+)'"*"&'!%(!)$)!#&'&&%#$&(**'('()#!)"!'(+*'+*$$)"+*"'"'*"##)*!(&)"''#*'(#&+(+"%$#$%'"*"&(")!'"'*%)&"!!'('+)&%#!"++*!&"&*+*%$*"##$$)$!&)$(('*%***!"$!+*#)(%!$$$"%#('!#!!)'&&$)#!#%'%#!$''$#)+*('#!#)!+"&%(+(#+"#
@r8477
NTCGGTTATCCAGATCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCNGTCGAGAATACTGTCAATTTCACCTNCGATCCGCGANAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCACCGGAGT
+
(?!H+37$2BB@)=*1BE)@%,83$5A-E5@0-C!#7D0(*-)97B4?3(>E:57E;+*D#8)9)'-<0H6!9;8D&E=:#"DC$"2;09@G<-C(H)5=&F$+F$$.7@&!8G'D38+0E0*E2?(G+
@r8478
GANTATCTATGACTGTACGCCACTGTCCCTAGGACTGCTATGTGNCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCACTGTTGCCA
+
$*")"+$"&()+"!%"*'$*&"&%#!#'"!('""$)%*(#"$$%&&!*"#$&"$!#*+'&$$++'%+)%(#"!+$*#+&#'"%&("!#(*'"$
@r8479
AAGAGCGTCACCTTCATGGTGGTCAGNCCGTCCTGCTGATGTGCTCAGTATCACC
+
?*%E8>$#9C%<+>,%4D%.@-++,;1GD"!0*F:441D-3D=%H</"4G7B!26
@r8480
CTGCCACGGCCCCNTGATTTNTCTGCCTTCGCGAGTTTTGAATGGTTCGCGGCGGCACTC
+
'(+*!"%)!*'!(#*#&"+&++$$(")$+%#%!)*)"('%&)+&())$''$("+*'*)**
@r8481
CGGCGGGTATAGGTTTTATTGATGGCCTCATCCACACGCAGCAGCGTCTGTTCATCGTCGTGGC
+
%2!:?#.;;B%3@@".<:4DD5(?)C89<?"+@+86E2G:;-+$82?%=:F>!/)A!4?=B5>G
@r8482
GCTGAATACAGCGTATGGGAGNTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGA
+
6HEE:0&G<42993%."H(-"$(A7*=/+,78*7#,%/%)70E/#A*),C+D0>,?CDEA(<3F
@r8483
CNTNNNAGTTNCAATNGANCTGGCTGTTGTTACCGGGCCACGAGTTGGTGATTTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTTATGCTCTCGGAATATCAATGAANGAAACACTTGATAAATGCAAAGAGATTCTTGGC
+
*!$#&!*%))"(('&#&'!+&&%("$+""%($+$$&($"++#&$&'%**"#"'&%&!(&(")%"#""+%*)#%'('#*%$**'%"'%)!&*##($("#**'!%#)&*$"'(%#()***!$&"()+"&%$'#*+**"!$**&$")*&(+$&((+$'#!$+)*)%(+%"$""#$'!#()$+%)(''''%**)'!"#'!%"&%
@r8484
GAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCTGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCC
+
(CA>!E+"E:AB,00A95&2.G'$!;8>65DF*>57=C2?A@%H%B"HG%B3F-7+9@.D20-H4+;288DE!8&-.?)93$3#6,>B9<H>0G5B;"H7'G/8HCE%'@B;1=;64=#:F@:6G:%:30.A*-'C:+D/>;;DC53C&??:/-B7,-&6;5;7
@r8485
NACCGTGCTTTAAAAAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTT
+
"59;7E'>D;,D;;:&D,;1+E'4!D"%F1)E#/*0@4C&15!(D(@-..4B0<'=<7%0&0@H&,5/!/,%-A
@r8486
ACGTTNGCCNNNGTCCTCTCACANGTCGATTTCCCAGAGCACCACGCTGGCCGANNGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGG
+
(&$)'#!%("!"($(&('%"""(#"+)**!#+&!$"#&+)'#&$!$!(!(*$&&'#(!"*%'')&"+*+!#*('()"%'!'&)#%!$%")"+!*
@r8487
CCCCTGTTGGTGTTNTTTCACATCGGAGACACCATCGATTCCAGTAANGTTGATTTGGTCGGAANCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCAACA
+
;"H>)8-(F8C.93C/).*3(.2)?EDF<7$G>FG;.!5%2(8-?$HBFF917>.@C/4#F;".$1=H#H-?<.2C9&-,#6;7AD@H='5.5#DB7>B3-9.E)*,2
@r8488
CTGGCGGATNACGCAGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGTCCATTTGAGGCCAAACGGCGTCT
+
HBG?7;":D5+"5;C8G)-%,5G%'83:/A!$'@BD<0/5D&+-=4=-40*'%4!HD-'"2)>6:'<=08&A&'5F-=A.')D405
@r8489
CGNCACGCATTGCTTGTGAATATTGCGTTCATTAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTCCGCACGAGAAACATGGTAAGTCGCGGTCTCTTTCTCTGATGAAGGCGTTTACGGCTTGTTGGGCTTGTTTAATCCAGT
+
)!*4->@6@G+H*A8*;6A@H&>&$C;4+/D;C"'7<3C/:81C88DH4)'.!.D>*:C0#61<@?C&@<3-'D7,*$.%6,5+A5..FD#&3(&86:&3-:153'"$%6F&D#3>$0$#D4*F>F#HB>E<+7E/'!F44/E*HCF8#C2G#00H>:&=,(.3>F5A/)?1%.@@H5".A8
@r8490
TTNTGGTGATTGNTCGCTGATGCAAAATNTTTTATGTGAAACCGCCTGCGGGCGGTTTTGT
+
*"!+%"&"'$&'!)%&)$++#*!#*+##*"*'&)&#(!*#)#)&'##**('')&')'&*&'
@r8491
CCCTTAGTTTTGTTCAGCTTNGAGCTTTGTTTTTCTGCGGGTTATTGCTTCTTTCCAGCATAAGCGGCTACCNGATACCCACTATCGACATCGGCATTGCCTCTGCATCGTT
+
0D#95=E8F=(H9.+3B';7B3<341;&A<+C"7">)%%E+!G4.AC#<259@*!$<,;%/D-#AH=@"0%#%E/5=+,)H>>'&E;G8G2=%.F.H6?*69$E1AF-C7;"
@r8492
AAAGGCCGGNGGATTGCCGCNGCTGGTAATGGNGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGT
+
F6/3$3A40%H?G9"G),DG?*E!'-<8;,B%%?6E4AF!B-7,F=.9?2%,."F+#G:64#8$D*C(B1$):/0%2+86)0/5B("BG-;)6?>;2A<H@>E.5%CF=<:#)>)H
@r8493
CATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGNAATCAGATTTGTTCGTGACCGA
+
"C#5!1&FG9>*#B+H9@H5$*-=!!,20,*'$=('*;D8H"#H&8B9-83@*((6@H7A
@r8494
AGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGGCTACATCGGTACTGACTCGATTGGT
+
B%$+$0/>;??)<71<BF0:;;**E-55,$4D/>'3-%1G=;1B%@3;:A-='858$;=AHBC
@r8495
CCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAATAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAACCGACTTTAGAAATATCAACAGCAGACNCAAAACATGACGAAAAACTATA
+
0HB&E8?4?@!+2*+"%D=,;B6C"@F9&9.+)%A<<5H-35G7G-C7;!*@A5@$B6%#71:>C0;G-4#F2B8F1D*&/!.*AB&784H#74=>0'$,.+;"&@@6%C<0@6D6#?8;*AF8''00:<.FF*?:&$(/:)>4:;4@3
@r8496
NCCAGCNGGCNGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAA
+
#$=06E/=<9"5+,-F<)41!5?,G*<H+!9F14HF;$)=B+1@>%'1851,)F5>3A+"H57$E'=F.$<9!9A=
@r8497
CAACCGCTCAGGCATTTGCTGCATTTATCCTTCGTGATATCGGACGTTGGCTGGTCATATTCATCCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGT
+
G*A$><#-@<:721%G%(H;,C.*A.::;,:/8+?('*5'F'6#1B2#.)GC:!!2?&(A'$'!<,?24>C.)%,>$6!09)A'*5-H'E26)(7?%23F2+-=$#!(=+)8/(=.8A?->5#)
@r8498
CAGTCGCGGCACGATGGAACTAAATTAATAGGCNTCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAATGANCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGATGAAAGAAGCATGTCAACGTAATATGTTCTAG
+
.))?1#5+:(&"1H23,#,:)3=@?&8;8F5,72)3+H(14"=)(6B)!1F:1=.1C)0<$F$77E?<:0*"0D0!9AAC2';C+>B)ED4A?+%"!0HC>"H#F097@:@#3C5?F/=,G:<B'4G:=3A0:#9E0>D<5(GCAF2#=-D>*H-'-3$0
@r8499
GCGANNGNNNNAACNNGCTNCNATCCTNCGGTACCNCGGTGATAAGCCTGGTTGACGGAAGTGGCAATCCAGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACG
+
"'&*)#&#'"&&&)!%*)'&*&$**))($'(*('"%')'+#*&&%"&*"$&""&!#+(+!+))!($*"!%&'&($"))%#)(%$!!$*$"#&*(**(+%'+"*('($$)*'$+"($#*!!!*)$+'&+%!'*&(+
@r8500
GCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTCATTCTCCTCACTGCGG
+
#D857&@,1F>(;HE#>8ACAH>4?>*+?'758!8->!,+DC;.E.5F.4<8C%1$E0>F/3?B=B()C>(@)=-AF;/H9*)*0,)G!2*59F5?:&A6G)75!B2C(4&-
@r8501
TCCANTACCGTAGCCTCCTCACGGGGGACAGAAAGCGTCACGCTGTACGTTTTCAGGTTGGCATTCAGCCCGGCAGGCGCTCGCTGAGAATAGCCATCACCAAAGCGCACCTTTATTACAGAAGGGCCCGAAGCCAA
+
'*(#'#*+#)!!&*''$##!&%"(("!)!$'*#%#'#*''"(%+%$###%$"'%#'('%("%*#$*$()&!'*$+)"))&$)+$&+$%)%!(#('"#'+&'+)*'#*!(!*)&+*$!+'$*'"%!'!+)!*&##*&'
@r8502
TNTTGCTATTTCANNCNNNNCACGCAGTTTCCCTACTGTTAGAGCAATATCCTCGTTCTCCTGGTCGCGGCGTTTGANGTATTGCTGGTTTCTTTCCCGTTCCTCCAGCAGTTCCAGCACAATCGATTGTGTTNCNAGTTCATAGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCNGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCCGTTTACTGATAAGTTCCAGATCC
+
$!(*"**#*$*)%$#'#$$'+'#"*'!$+#+%*!$!)'&+'!##(!*)**(+))+"($$&)'#"''+!($'+'($)$)(+*&+$*)$)+"'(#!)*)*'*("!#''#!*!)))#'#!+&)'*)*#)&'("))&&+*+"#&+&+#"')%!#$&#+&!'(*&#$+&!&#&)*$)&#'"&'$"*'""&++$#$"&&*&)!+$*#+'#%!!+"+'#($*+&"('$$'!#"%%#+'*!&$%'"!!#)'(#'"''++$'%")(!!+")('
@r8503
TCAGGGTCAGCCAGCAGCATCAGCAGTGCTGACTGAATTATGGTGAACTCACG
+
0(&:G*A$:H2<C'/F29=9,<D%E'!,,%A7-*BA&F;+&:?>4H)3.///$
@r8504
TAACACNATGTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATCAAA
+
,*.@G!&578*9#%!H62?5*71/>,="591+*0!;)(:C*3>-B=87@-*1F'7'"E8<-$F29(HG,<B')771(4
@r8505
GTCACCGGGATGGCGGAAGATATGCAGAGTCTGGTCGGCGGA
+
#2;!1"2D*=A),(:=70#>'1H*."4'@:'3?>2*AC3%6H
@r8506
CCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTACGATTGGTTTGGTTGGGTCTGGAATNATTTGCTGTACTGCGTGAAT
+
-"@<;$')DG333C;.:!6(9@F"-#3";:#1@>+!&91;GE4/G9C+6&EB<%D+*:(@)"8+3";"'?**)<;F&&-7#:57)//,(0-9#<B7'F04C
@r8507
AGAGCTGTCGAACAGGGGGATGATGCGTGGCACAAATTACGGCTCGGCGTCATCACC
+
-H4/5<=BB))3C?A=!!4&848F&$FD@+?C*#C@GB5@$%3$.@+AC:'6?#6B8
@r8508
NGGCCTTTTACACATGACCTTCGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAA
+
!4@!H65G-F%)*07EF6F-5,"FB-@C;:040#;*+);#4"0C:7;7/!9D>2!
@r8509
CGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGTCGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACG
+
$$>?1#8CH9DC><D)70/63B45:#?G-@.#85(+D6A4&@;;FF>9C!+%>&F=5E&8+1=?24<<>(G142(+/<A=0#4E$$H1(.-?1!77>1=&&0',GD'1C#BA*A;6,C?=
@r8510
ANCGGGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCTGGCGTACNTTTGTCTCACGGGCAACCTGTGACGCCNACTGCG
+
)(''!+$*"&&$'"#&(#*#'*$+(&')$$(!$$!"#+%))('#(#'&#$%*"%&(#*(%((""&'(')#!*!)#*'"!&#+''&
@r8511
GAACAGAGTGGCACGGTGAATGGTGNCACGCCGCCAGCGGTGCAGCAC
+
*C,</*'*0>!+71F:>9%'EG@-)C01/:,.G22?G+/5&:G899?/
@r8512
TGGATAACCCACTGTTATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGCCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCG
+
/)/>1@@1D&)56/$$E<2=:->F04.=<9!/?$G=2!/<33$06(0,?7C5/A:(6./,D.2+HA><#BB0<!$'-/)0#1.;@#'H?1$%,9A,"$1H5&C@./"&&)=)4)D
@r8513
TTACTATCTAGCCACAGATAATATTCACATCGTGTTAGAAAACGAGAACACCGTGTTAATAANAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAAC
+
,?C&<1:72?"%C7CD'$B>A1'"/F%;8=(1H-HH;;B=@'!%%11BB@6<)3.F'D0#B;>!G=),#25='1=%=)@D*4DB(**-H.:;(1*(7E8#/B4
@r8514
ATCGTTAACAAAATAATCATNCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGC
+
+)A"$=>*-+>G4,@,F(&34F92C2A1/6B%=GDA>G7*)7BF!*4B777+3<!$$;B37F!8AG#HB
@r8515
AAGGCCATCTCTCAGCGCCTCTGAACAAGGTCACCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTNATATACTGGAATGTTTTAAAAGGCAGGT
+
H*.<#%1A203:3,89@7B0.:0:&F0(@?'6$'!:F?##>%,@HH&F/?,.#:B*<//&03D+.**'GG!*#7$?;8H)?5@</>)F8>$D:<7<@,#9G<(*$F&/8(1E8"(
@r8516
NNTCACAACGTGATAGCAAAACCCCGCTCCGGAAAGAAGTGGCCTGACATGAAAANGTCCTACTTCCACACCCTGCTNGCTGAGGTTTGCACCGGTGNGG
+
!+!)&(&+(&$'+#+#%$&()$%*+$'&#&%((*##)!#)!$%+)+(++%)&$$&(&*)+%#$#!(+'#*(%+&&(&&+&%)'%##%++(%&+$$*(!$$
@r8517
TGTAAGCTGACTTTATGGCCTCGAAACCANCGAGCCGGAACTTCATGAAAT
+
97D,4)'<F3*?:C37CBBF=HF*C1",84.HB<%<H%/:;45;$=;$C!#
@r8518
CGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAATTTCAAAGGTTAGTTTTTTCATGACTTCCCTCTCCCCCAAATAAAAAGGCCTGCGATTACCAGCAGGCCTGTTATTAGCTCAGTAATGTAGATGGTCATCTTTTAACTCCATATNCCGCCAATACCCGTTTCATCGCGGCACTCTGGCGACACTCCTTAAAAACCAGGTTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCA
+
F3(F9H$B<7,A7$E2A1!.5A-;3'&,"08)HB6,;>6=309%;/,+<#;;'1!@F+@"FB<+09</)1>#35<$>8*7H8,6';2$4/'&5*;"DG-#$$?80,/23GFB1$F&$'A6%A=0C@/(!B&#5/A(:%(/A9+2?(''/B+<+G;4$2-##A0-"2H>*1$6F#7D&)<7G7)2!DA.E:;(%6</><H"3#C>&171AF"2GD'2$760<H-+&$:B?&4=#D)*:8'?E4=/920:<>/@2(/7%3A?.5@2054@2H++=D8CE5E)5'?91=
@r8519
CGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCC
+
:447+H$7-&B+@D?HBD#'&1C!%3-5(8/GE6B<+<=7B)F$1H!:D"A5%5(<-;(B"1
@r8520
CAGACATCATTGATTCAGCATCAGAAATAGAAGAATTACAGCGCAACACAGCAATAAAAATGCGCCGCCTGAACCACCAGGCTATATCTGCCANTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAA
+
C#E06G><<&+!95<)&&:?6H"#D$)/-<:$!)4E435!58,;2!/=6=10:7#D;27?3+4G'(7G=CH8;))#);*"(5%22,2*3D(@;&<@=;"&9/6=45(:A3:260?5)#G9!3"F";$H#H&?
@r8521
ATCNGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAAT
+
5%D1*$#5-F*,G?1:0$B7$-?@6=4//<<:9)*645:HC#"$#)7*C;
@r8522
CAAAATGAATAAAGAACAATCTGCTGATGATCCCTCCGTGGATCTGATTCGTGTAAAAAATATGCTTAATAGCACCATTTCTATGAGTTACCCTGATGTTGTAATTGCATGTATAGAACATAAGGTGT
+
BFBH&?,>0"<G0:D0,,6".F:4?1!:=:19)#!-5'F/5C-;F?=5"/7*#0942;8%).9!283!F:7/&D1?A1/)2H!6)74A&32"!1A;DD2:HBE@9<8.*,-"6+4,#$9,F-C!)FG&
@r8523
GGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGT
+
-)1,$#'H:$-FE8@3?C.(17@13</.,7>H'$G1HD50H
@r8524
TGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGAAAAGAGTTATGTATCAGTGCCTAGCAAACTCGGAAGATTTTTTCAGAGGGATCTAGAATATGATGAAAGATAGAAAATTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCTAGAGACAGTGGCGTACAGTCATAGNTGGTCGGTGGGAGGTGGTACAAATTCTCTNATGCAAAAAATCTGTAAAATCGGTAGCAACTGGAAATCANTCAACACCCGCACTATCGG
+
B5&+%--"F?&,?E+1'/E8<#::25A3$*E,D)$G+0,"F!<,2$7)C+E!G8B.E!0-40*H"H8)B@?*5A"4+?5(,@H/1)!?&DH;%D?E7?$F2$AA?5.0DB3C240H$@C>-?()?)&:%>.58C3/,,BA>B(3D54G963C@H=!./6999@84G;=(;?>?H)9'>&7%'"%5:6)$,1>2E:/0H''%=$0(AA44:7B%/D$H01B;8+!#*(7$--(*)53+,965C&@;H:"'/72@2C<6<@HH4G4(F.>B7GA!E?@7G6-9G=EACH:F5E<*C17<.<D$$=:9/B)5E-C?=:&B+2G-5(>6E)7/11/H+D+=(*B9$!!1A;=>%/H:@-:F9&@(81A&@:4(:4'?0*,,!B88$&565C..3F-($?1"-+1-*(3*:8
@r8525
CCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAACTCCGGGTTGAT
+
>**>)@><548D0$%:7F?C0!+4*3;<F',E=5)*$&D2>4FD>@#$3.28
@r8526
GGCTTGCCNTANCNNNGNNTGNAATCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAANAATCGGCGAAACGTACAGCGC
+
)#'')*$&##&$'#&!($(*##)&+(*(+"$&!)$%$*&**)$*)&*#(*!+'$*$'%%#)(())&)$'%#)#)"*)'*+"''&%(()(
@r8527
AAAAATGCATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGNAAAAACTNCACCAGATTAATAATTTCTGGT
+
$*+((((#&*)&#"*##*#')*))"*%%$$'*"#*&+$!$$*#$'(%!%%('$'!#%$!&'+&'&&!*"**'$$(%"&)%(#!$*()#)&()!&&+*+##)(
@r8528
CCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGC
+
H?=5A#57'E%31F,?H29<(B5<A'HD$(=G9::=<?81;F,*0?&5./
@r8529
TTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGTCATGTTTTTCTGGCATTTTCATGTCTTACCCCCAATAAGG
+
.D@=%%/305*5'@G<@C62;),A@54;H,:'F-:")E'1!B!,=9*CH6,E**$+#?-7#CD1B.H.%F7GD3-6A2G)DC3#49HE"C,D:<;-*)+9+</B:=)0A5,6"-*1"(!.=-;G'2,G;1"$&,5%#45F06F0<?.
@r8530
GGCGCAGTGTTCTGCGGNAACCTAACATTGATTCAGGTACAGGGAGAAGGCGCATGAGACTCGAAAGCGT
+
6+C2C#;=%'G2*E8?>:)%AD(9.HD1.)<A>:)%/5+@<3"'/:CB$?1>3B497BH:8%C'/?7DA!
@r8531
AGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGNGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCC
+
C+@9'*C.@?<G=/-6*;+F0=!$394E4512E8CA$"D+:<4>!>H7$&)-?2%,A$'-==&->;>%>E<EC7CH'5?$,37/:H1A&4E&G0/84>)B:'/-;A%DC.B#3*)F*2734.<%,76+?,9.;=9'F6;4.<<==@(-)=90DAG<@FG.B=84'@&3C)%7A+,!B9;F)D)"<3;A
@r8532
CGGAAGATATGCNGAGTCTGGTCGGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTTGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCNGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTGACGAGTGCGGTTATAGCNGTCCGG
+
5!FAB128<6E5'6:>1)4(=F3*'<1=B>>+'<>,H9C=:"E=01=,#?@.8@"8C2H(;!06@*A4F,!D"+=(>4F=-3,9#D94.11FD5+FH88)(D64D,G=-4(;!?$(6D5D1*37'50?F&%:C"D$"".?E),1@"0*1G4?1+%H*!H6G(FE21:4H390<0'%H7::8<<G&3B;/;.9CD;;>31E24)-1-'*64><%3H@&@H70:;#5?E7;A9@'==*3;H>)$H1&:D'3B#$!#"AH=*B.D;<F/A0.$28#0EC0F:14F)G3,6$
@r8533
GTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAANCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAAT
+
G>>72,>#?8F)-<"80="4"$.8.8+3@FA;";:893GGF2D'8)AD+'"/'=B0$4.>=%@;0DF$6?$D./A$2A5-"39H0D6,A9F;<>@)E&,(34,1@-7<!4D.6FFDA8B7'3)7$?<!*@:#E27)'=-1>D&E0:D<+/.82<</$.9-<0507&1&+:&
@r8534
NCTGCAATCCCTCCTCATCTTTGCAGGCAAGTCCGATTTNTTGCGTTGATTTTTTAATGCAGAATATGCAGTTACCGAG
+
">AD"6@D24:G+BG8;;/=9<,@!6%F2B!.G!2456HF1B*?4"!AH&DF.3#4G4-C362@*'3%,%9'&,H=?F$
@r8535
TGCCCAAAGCNCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTANCACCGCCAGAGGTAAAATAGNCAACACGCAC
+
:<:?*>E%+H+;@04:&$@/%7*@/B@&8!;"B#;:8(<3#B?B+02'G#,.:392&E$(0@&&+?*6</*H1H@-<(H/G9H=.<+<.0B4-.=H5&!1<%5,/8G
@r8536
NGCATCTCAATCCCCGCCAGATGATAAGCATCCCGGAACAGTGTGTAACAGTCCNTCACACCNTGCTCAAAGCGCNGCCCGGTGAGATGCNGCACACAGCAGAACTTATGAATCGTCCCCCGGCAGNCCAGCCACCACGGCAAATCACTCTGCACCTGCANCCGCCGGTCGGCCTCACTCAGCCAGGGCAGA
+
%-9H)8%36<F0)9>*!<B"HA5)36D!G;"&='B3<+#=?60.D:%,2+1A+="6.H<:*"H/30D#:4DDD-4=D#2F"9EF**">E!:"$.',#?,$A'%?;5(/!'HD?A@1?=F<D2H)!D2:'A++8)1:)%$,0*:#H@26GA,8C-0<1%<#:8H63:CG.&2%E!70!2C/0,9./C7!(C$0
@r8537
NATGGTTTCCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGNTCAACCAAATCGCCCACCGAGATAAGCAGGT
+
!;9.-?:.3;<).5(1-9#H6C@4@F1#5:$(&/%H'1G'*&BF>#<A0:;-,.G7,A=B/B-!76D;!E?3)/2&4**!!?(G?$2(9++4<8<$A00"20./A
@r8538
GAGAATTAACATTCCGTCAGGAAAGCTNGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTTGGTT
+
*%927&9=-*>);%()#3!E7-='<$62C8)$-G'?*)<@2DC/;?.#A*./?,-?-E*/#-6$$DH(E7-F$9&E),F1)<BG(/-&;?ACA7GF%.%66))+*-
@r8539
NNNNNTCCNGNNGCCGNNCNNNNNGNANACNNANCTCGANGNC
+
"##$"!#$"$#"!##$#!$!$!!!$"$!$#!"#!$$$!$"""$
@r8540
CGACTCCCATCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGGTGAG
+
>../A:&)7?F;)=(E%?,:5<1/7$1>'FAH&$,A;<-G38G>AC?A5C</,)=
@r8541
TTGATTTTGCTGTTTCAAGCTCAACACGCAGTTTCCCTACTGTTAGCGCAANA
+
?4"CC/<=#2D3>-5+1H2*:AE#0;":=&%&,D35C:?*C-%FE87D!@!)H
@r8542
CTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGA
+
,8#B<6=!,1"FC8)(G,@/=39*E@B&-/@-6#@@-",4$A;H+2>0>?!'#85+.5"@"DA15%$D?)+!
@r8543
AACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTG
+
8A)+B.C?1521@&@-7885/?=@!=9<#?C8"0!A?BHC:4DA"G4?.#<(A%*0#6""*$@66#/E.1("#<#8"27.FG;/<"/#G"$>7;9<:G=<."61DE$&H<D&?F29<8?,0F-.CE",:E
@r8544
CATCTACATAAACACCTTCGTGATGTCTGCATGGAGACAAGACACCG
+
,?E&9*+#/@,>8<E:A087-@(</;13*4'%$'#70CE"AH+&;73
@r8545
AACCGAANCATTTGAACATAACNGTGTGACCGTCACGCTTTCTGAACTGTCAGCCCAGCAGCGCATTGAGCATCTCGCCCTGATGAAACGGCAGGCAGAACAGGCGGAGTC
+
+(++#%#"'#*!&&)+*!%(&)+"#!*(%"!#+!"""%"""!#%(+#$&(#!$'#'*)'''%*"!$)+#**'+&)%)'+"#"''!%&'&#(%"&$##%%+&$"!&$''%()
@r8546
TAAGGTATTTTTATGACGAGCAAAGNAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGCGCCTGCAATGACCCCGCTGATGCTGGACACCTCCAGCCGTAAGCTGGTTGCGTGGGATGGCACCACCGA
+
%*'(*%*(#+'#"$*&$""!#"$')'&#('$*'*"#)'$#%"##((#$$'"$++*$&'&*(&%$##%)*$"%"#!*'"%%$(&(!'(("#)#+)&&+*$&!'+%()"+')'(#"$!)+!+!*'+++%&+*%+"$"!"'')#""'*%#)()'+&$(!+('!(!()$)+(+$)*!#"&
@r8547
TTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCTTTGTCTCACGGGCAACCTGTGACGCCGACTGCGATATCGCGGNTGAAGCAACGCGGTTAATGGCCATTGCGGCGGCACCAGGCACCGCCGTTTTGCTGATACGGCTGAGGTTTTCAACGGCCTGCTCAAGACCTTTTATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCANCTGCCGCACCTCATCA
+
=44H19B4%,GFHE-B?#@<7*DF$?;&&$4*28+&:C6C7),A3'%+2%7,@(@@5$0*6?B0/04.!6#,34*!46(2'.>DD)E*#1H2H8D1%)&;((=7/'&>(,.8##G5=@G,3)=95&A/-E);6'!6G3%60>H'=(/*,:H!B#C'AD!4(FA3GF%%5B5A.'!@D@-%H/;6>21#(H?!%)6/B$&-35-G(5CG4((<H&2.(3?%(%E13%?;:A.H(;G;=22!#!=!8A+4>--:(F'9*(*E8D/>%%)H"40F(>47#%%.+6+#6@0"(G:6(%,3F36?'+$,=!'0%1G&%&'$8C0.7=-<;1:%"(25DDD.C95%'(>"<;8;6=HB/"'6&'-#%
@r8548
ATTGCTCGTGGTGATATCCGTCAGGCAATCGACCGTTGCAGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTC
+
;F4$>A1-BBA-101,-0!B!=*7>+:7127>$$5=?!%,13:?6$;"*@72*A(5:C6).H<,$-</3=D%<'6>:D=
@r8549
CTGCCTCCACCGCGGCCACGAAAGCGTCAGAGNCCGCCACTTCAGCACGATATGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAGAAACGAACGCAT
+
0:@(>98F*8&(H@B'/"E+;!C$>5$<>18;,&%50.(><.D>?7&5A)A>&4D,()5G>;$$(-8#:A:9,>8,:9.?B/"5='C.,>)77/!><7F
@r8550
TAAATGCGTGGGGGCAGCAGGGCGATCCGGCGTCGGTATCGTTCCGGATTGCCGCACCGGCAGCACCGTCGAGGATTG
+
*$(+#'"$'#'+(&$)+"+"("#$"*%+%'%+()$+*"#"!$&)%$#"'("#($&!$#$##%+))'+(&$')*!+'()
@r8551
GGTAACACCCCTGTTGGTGTTCTTTCACACCGGAGACACCATCGATTCCAGTAAGGTTGATTTAGTCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACANCGC
+
+&"+%&(+&#+*%%&!!(*++%)!'&"&#+'+!+*#'+!%&$(!#+!$')$!)#$+!%"+'&)""#+$%*(+'(""+!%'%#)+'*&%%%'&&%#$#+)&#)+'&$''()'
@r8552
NGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACT
+
!+DD)=.8!G*!)G$HC>!DB=E>'#?&+);))8>30A0=>C;;4.!.!F*?EBA$2%92C6HE00"+D;B)8B<
@r8553
NAAGCNGTGNCNGNCGGCATANNCCGTGGATNACATCCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCAGTTTCAGGGCAAAACTCAGCTTACCGCCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGTTCAGGGGCATTATTCACCACAAACTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTNTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAG
+
!)&*#''&""(""!+")$+$++)*(')((*+'#&%*!&*!!))%!'$*+%("($#()(+)#&('$(+%!'!&%'&"#()&!!*""($*"!(+$'"&)$!%#''$$+*)**$$)!*)#+)#&((**)*!*")(+()*%#%(((#%')(#&"#+(&"+%!#('!"'+!&*+$"$")+'*%'!+++$''&+"%)+'(+)$#'("(%'*)'(!%(%*$"!&*"*'#+*"*(#+'#)$)!#")*'!**!$%%!*+%$##(#'&"((+*"()%"!(#(!!')!'+*$"(#($+(&!$$"%+*$$+**#!)"!!*#*#'+"+!%%)+('(*$)+&!*)&
@r8554
ANGNCGCTGGCGTTTGTACTCCAGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGACTCCTCCAGTACCGCGAACTGACTCTCCGCCTTCCACAAATCCCGGCGCTGCTGGCTGATTTTCTCATTTNCTCCGGCATGCTTCTCCAGCGTCCGGAGTTCTGCCTGAAGCGTCAGCAGGGCAGCATGAGCACTGTCTTCCTGACGATCGCCCGCAGACACCTTCACGCTGGCCTGTTTCGGCTTTTTCAGNGTCGCTTCATA
+
*!&!!*+#%''""#((+)$$)'"()#*($(&()%#"")"!)$!#***!&%("(#+#)')&#'&+"'"''#))*%&!)"(*''*+$!'&(!##+$*$)!%(+(&)&**"'*""'$+&"(#%!!'$$#($)!''"+)+%*"$$&')&*'+%'*#&%!%!#**&#"+&'"*+!+)&&"&!%%&%"*$+"$$')#+%%#%()+'$#&&"(!*'")%&!"%('+&'$')%+%"!''$+%%'+!#)$#*("$"*%*&++*&"('$%&('&%+!$%)*"*""*%#*"#""(&'!+!"'
@r8555
NGNGGGAGNGTGTGCGTCGCTGNCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGNAGTAAATTGCGGCGTGAT
+
#*%+""&+!'%*##"+'$!$"((++"'&)$#**""$%+%*$(+'#&%(&**%#*'#$**")%###+)'*%++#++*'%*%+!+(&$)*)+("$*)&"!!*#""*%$)+"&(
@r8556
ATCATGTAGACGCTTATGCTGGAAAGAAGCAATAACCCGCAGAAAAACAAAGCTCCAAGCTCAACAAAACTATGGGCATAGACAATAACTACCGATGTCA
+
@.6/A*'28-5*<B!D"/+%((<4?>9.:FF%1/+@@)B9%"D)BFH&?)6-))$(GB',(GG1""$<5EC*3F4(G4;#!+-434E&6+@=A#2&%CHB
@r8557
CNTTTGCCAGTAGTACTGCAAGAGGTTCCAAANTCCTGCNTGTGGAAAGTCCTCCGCTCAAGAGAAGCAATAAATATTATCCGTCCG
+
'"'&""+)*"'("$)#!"'#+&&+++##*#'&%$$##$('"'*&*)"$'!&'&%"#"($%##&%'&%#"+$"'*()*"!("'#!#&+
@r8558
GATGAATGCCGCCGCGAACCATTCAAAACTCNCGAAGGCAGAGAAATCACGGGGCCGTGGCA
+
@9D5/E#+'H1@,F0=H;92/@E2E250&#F9))C0G15<2@$H"#4?(?A62,2BA(:.=-
@r8559
ANCTGAGAAGACAGCGGAAGCTGTGGGCGTTGATAAGTCGCAGATCAGCAGGTGGAAGAGGGACTGGATTCCAAAGTTCTCAATGCTGCTTGCTGTTCTTGAATGGGGGGTCGTTGACGACGAC
+
'&G:>:+(@1G()//*5.-E.&H+)E'HE<"HG&?E<A#67@&%'G2(55)*C24,0C";<39;A%612?B<8E,<&#A+7)97:H&@FF@<.H6)@C.?"!8)"0'&F+3*B(#;3#"/"*-6
@r8560
GANGTTCATGTCGTTGGCAAGNGCCCATACCNGTTTTATGTCACG
+
(#!E<(*==E6H;6>>,3&-28!D/0&7&:.(;?;.CGC=<G(+.
@r8561
GATTTTAAACTATTGCTGGCAGCATTCNTGAGTCCAATATAAA
+
0==F>?:(F1):H,5$=+1-"(!==<%F9!57.*H+,E.?9($
@r8562
NTGAAAGTCACCAATGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAG
+
#2C2$D++@8->(D,B@1'/0*F3DCG3"5D:.87$C!3')9/$-C=3#+)*3=,.0;
@r8563
TTCAATGAGTCAANATCATNCCNTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATANAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCNTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATNTCAACCGCACGGCCTGTACCATGGCAANCTCTGCANCTTGCCCCCGGC
+
&+0)71=<=+<!?A)DDC@*;+4D,%37G&/*":.<1532/$$;-+F%'1A&+FC<77!<>+?$A,2"2,5?H.?C(C+C38?6?)+EC"&C5'0B'2;402/5,(F80<H/673(6?4E6B6F%=+8#6/=+*@;,E(=C-#.&<H;5"=$HGD!!.3%27-%-9437%E#9<,)F?$02"#3*@;E!28H%G+F2D1<#&#94/-%0E2%"C'8'!%#H9CD+F)$6((22@%(;A6?!7AH)-,.@5)0:*/+EA/B-22G:&,5)('=/!!%H(+G@#535=;E+46!H#(".:);(.*D7&G77>#"1$*5>!E!DC6*.-E821:A9'H=95.D)D$6
@r8564
CGCCTTTCCTGATAAGNAGAATGGCATCGTTCCGGTGGTGGGCGTTGATGGCTGGTCC
+
7797")GE5&DD!FBA2;5;.19D7)0<!/)=5D9,.""H3%3:3'7/7#5=069-,>
@r8565
GGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATATACCGCCCGTCAGGAAGAACTGAACAAGGCACTGAAAGACGGGAAAATCCTGCAGGCGGATTAC
+
85852-3<3+.7>"$@$5A"$7C147148-B092C8D0(:,C=G<CC;E>0:?5#7D.=3.7)D)A-85G,<2#%284?8',8@=-A,><9<4EH9A??+
@r8566
CAGAATNTGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTNCGCC
+
+C/"*G@E;06+#"4F'7/GDE1A;%+$0/H(1$!F4<'*2-,;&3)1.9-G(%/?8<?;07.5*6?HEE9.'!4$%,-5
@r8567
GCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCC
+
)>$33@<0/2)(1B*>DA'0&#(H@)<18;-CFAD8@+%1+8G2-0';'4*#0BG.%?);4-$A&!9@%).G&1+H->17<#"E)';6?B8:-551+E9(
@r8568
NNGTTGTTGATTATTATTTGAATCAATTCCAATTNCCTGAAGTCTTTCATCTATAATTGGC
+
&$+")++($%'**'$+!!')#(#)*!)+'(**%*"%!!+%'&((("#"*"()+*&&+(&+&
@r8569
NTGCTGAACCGGCGCGAGGCTGACGAAGAGCCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTT
+
!C70<;%2B9?0.G+.?5/'6$D;E1F=2GB3</*$?=;5,4$B-:G3?-=G*<D@0>E/!2>8.(,2"&GG34?9G!$4$,5F5%$
@r8570
GCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATGCCCAGCACGAACATTC
+
>'8#BGC$7:5/=94E30,3=&%%9D@:.FDG8G-!)$/8)=8-/@@>=.1)+0G#!?:@=)-4,8)=0C?'#-.&"!"%@:$)C/&::!,+E-);H)++.+5B@B2C8HG).B7.2."<&%-G17-E="7%$B);0B"/+<HH>6!*<*1"7$>'HG:(F.CF"!F%4;F/CDFE5E*!F%%+6-$-,:8,9='$D%GA89D+#-*%.FG
@r8571
GAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGC
+
288%()-*,($;H+D39A?3B;$H=H=4,CA7>%E&G6%)2D7+5@"BH+6;.$&)A4E9;64*'?%GD;<5)4<84D//?<C1!36;/+5(*/,0:6#86
@r8572
GCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCC
+
$00E-1E<FGG-'<0)H29,!#')6?/05/A1202#>5%>?9EG1>!%/02%4"E95.+A7-@D8?%!@
@r8573
TTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCNGGGCCATGTAAGCTGACTTNATGGCCTCGAAACCACCGAGCCGGAACTTCA
+
#?$(?.F(@'9!*B&!8-G910$?F'518%FH;.-26!,'<H0EA>E@-.2.63,C*A;B+*A/89'),@3.B,#>E)E7+9B&;#B38A'.6--"49<DB.>)*4?HA%*->B!A&??,7F#%(/4-(=:0E4"%$!D-E.&>??24.B87?50%-GC9"*
@r8574
TGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATNCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCA
+
6C*C-!E#F#1+FD!";);$'%3-A'/0BB!<)9";&1;?<=0E/32"H0=$2-676"()E=,:A,6,$-E+6E5"04@8B:8A?9/E5A0F?"<094H2$'/1,4>=::1132,1(9.5@6:A5"8'<=62C,
@r8575
TCAGNTTTGANCTNGCANCNGGNGNCNNNNNCANNTTNNNCTNNTTNNAGGNCNNCTNTANNNNTTCNNNGNNNNNCNTTNGTNGGNTGGTNATANN
+
"!##!!"####"#!#!#!!"""$#!!""###!!$$"$"$$$""!""#!#$"""!$!$$#"!##!$$$#!$!!"$"!$$!"!!!#!"!$"$""!$"#"
@r8576
TGCGCTTCGGGCTGACCATCCGGAACTGTGTCNGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCTGAACGAACAGTTCACCGNTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTA
+
0,G);&56>%88.7#5)'9?7'%1),47%H%D"!.2#=D7-=F50<EBDHA62*9'.E!D(>B3*F=>5<2&#00=*>)!,)63;="-5@83D;H%#43D9/$"4=7G:E9G<67;/2.)#7=0;#D1
@r8577
CAGCGATATACCGCAGCNGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAAT
+
/$7:F'8?+"&:6&0.100,G%C$D6:,,&"?.<?=;,?-,>GA5@H8C"2-6/*&009*1A,5;3*5"72G560;2DC68&82G",<'7-A23$)(*$#'+#-B8+!6$;4$H2)!4'0<-.E:93$+8>':#&?'0&&-
@r8578
NATGACATCGCTGCGCGAATATGCCGGTTATCACGGCGGTGGCAGCGGATTTGGANGGCAGTTGCGGTCGTGNAACCCACCGAGTGAAAGT
+
("*+#'!!$*%*)*$$*&#($'#!(#(#)'#($$&$%#"#%)*)%'"*'''+"(%*#*#!##*$!('+*!%(&!!&+%+"&'!%!!#((#)
@r8579
ACCGGGGGGATTTGCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTGAAAAGGGGC
+
-+;E/F;0!&$<B%2E":*57-6AEH4&'(F&$';H*:;9HHA6@?4;);9>-#=FA;B,A*E(H+:2G+(#)5%/6-
@r8580
TTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGCTTTCTGGGTTGGTGATTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGT
+
2$BA7$F6)G$52?9@@'1(+'#4:#.H<(H6(=+8>9C<F7!59:(5*<;FF?$</>>D7)!,4B;)6-/9(E?9:*75=++<0<&0.A0E@"?FD//9H@H"5E*+?E99>$G?E>:=()@3,G>!.<=-A
@r8581
TGAAANGAATTCTAAGCGGAGATCGCCTAGTGATTTTAAACTANTGCTGGCAGCATTCTTGAGTCCAATATAAAACTATTG
+
@7(!GF?0/2G;G-.8.FG?G*F6E7#2&58(-#72D#;*>0E!-8#*B3:?4<:3C:@:5EB*544%%F6916:4$5<6!
@r8582
TTCACATCTGGACAGCGTACAGCCCGTTCACCACCTGGGTGCNGATTGTCAAAGACTGGATGAAAACGAAAGGGGATACGGGAAAACGTAAAACCTNCGTNAACACCACGCTCGGTGAGACGTG
+
4>:'0(+6<@7:,?CB"4.5/%818#(=A698)&7H!!:0B$B<1%*7+5:&@G%9*$#&*@2&+=0?@"13%B7"(7%(3.'6?",@91D5>2&;!#6%<&;CG+F/*F5,E%=0/EFDA:?+
@r8583
ANTTNCGCAGANNTAACGGGCATCAGNAAAGTCCAGCTCCTGCT
+
"&$)"')'*&'"(!#+&#)'&$&)((&"%("!(+(*+*)$!##*
@r8584
TTATAACCGACCCAAACGATGAATCCGTCAGTACGCGAGTCGCCACTGCCGGAGCCTTCATANGCAATATCAACAACGA
+
:5:CF#.E230*8,F324B(=A*E!1=7;?)4+*@4-)?H)1E)"+4H=)#54D*!18!=)18!!+$9);92?A%:C)3
@r8585
GGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACA
+
H/B(6/!-$;)%:B0FF.G4?":;&4FA,;(-5-#0$=(D9>"B4/E--=)>9D7?.%1$F@'@8&*@59+@!+2+E>'8@(14@9)%BA-2F0BH-?5#)@,?,!4(3E053D.%80H>8)AHA8.*;+
@r8586
CAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCT
+
0;(B$$>4ADD83B(&9D<"2=!6FA%,"$?F/,+4!!B73-->H=F.G$D9
@r8587
AAACAGCCCTCCTCATNTAAAAAGTATTCGTTCACTTCCGAT
+
0)?<G6GA,<5,2(5C/@;-7H>B"3A";G8"5'5GFC3!?6
@r8588
ANTTAGCTTNNCCCACCTGCCTTTTAAAACATTCCAGTNTATCACTTTTCATTCTTGCGTAGCAATATGCCATCTCNNCAGCTATCTCAGCATTGGTGACCTTGTTCANAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAAGGTTCTGTTAAAATATCTCC
+
!!$'$!$''"!+%")%"#&'!+(#%++'%)+$#&(+#!&'"()"%'+&%&%!#(#$%*"*%(*#%!!$%$''!%*+*$'%%("!%()!%!(#$#'%&!&+*(!!'(#$$'$++*"!'""'*!)($!%(+(+*!(("%*%+&&)'%$'))('+(%'#%%&!"*+
@r8589
NNANATCAAGACTTACGGCTGACGAATACCTGANAATTTACCAAGCAGCAGAATCATCACCATGTTG
+
"#'%')+$*%(#+"##'&+)#$%"'&$'"#"($"$$&!$)'('!)!%')'*)&($%$*)%&&#+)($
@r8590
ANCGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAANAA
+
$(#(+#$#)%!%+##)**("%+)##)!%$++%$&)#!(%+$#"(#*%$&$)*&#!+)"("()"$""'$*!++'"""&!*$$*'&)*&*%'*'&$$"+$)!&$&")$%!'))%$&
@r8591
NATCGCTNNTTGNAGAATGGGGATTTGNCTTCATTAGACTTATAAACCTTCATGGAAT
+
"&%((*#""(&'!#+)("%#'!'+(%&#"!($#&*'%$!)"+*$&(&+)"#%!#!&)'
@r8592
GNCNACGATTGCTTGAAGCTATCAAAAAACTATGTAGTGATGAAAACTTTTCAAATATGGAACTCATCAGNCTCATTTCTAAATATGAAGAGTTAAGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCANTAAATTGTTTTA
+
%!*#%(%$($'+')"!(#$*(#)$#'#$$$(*%#+!)$"'%#%#')+!*%!#+&&&))#&!)+#')!'#'%!+!'*$$%%(""#!$$("$&*"$$(**&&!&((%"*%"('(!!)&"&&#$!!$#++"$("*#**'#*+##+'$"&+"'*&
@r8593
CTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGT
+
<4'-0+D:/DE3662:.@9A4,C<?DG$:,FE885#?.95C#(2%"#H"(36!/D,D8+=/%)9B1(.D9%C"7"=2(8EA>2&+;,".E:D=EE>/:7%<?/A6F-?/1/<"3?;C;B82EA(H@7+&:"6=/-+F6,7:1;2A':<1?2B)2(H=G*C$H77G-9B&3(G'5=9.$B.GF#D@75)9B&7GG*CG=&C?*H5)&8+@8=$G3
@r8594
GTGTTGTCCGGCAGGAAGTTCTTTTTGACGCCGTTTTCCACGTNCTGTCCGGAATACACGACGATGGCCACATCGCCA
+
)(&+!)$!'")""&$!$(()$$(+"$"!!'"!(##*##$!+#&"**!%&)(#"(*+&*##"$&*)#'(#*(*'&(($+
@r8595
GNGATGTGGCCATCGTCGTGTNTTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGNGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAAT
+
##G<G01G1%,D#/&,@0"4/CHA-8'H/6B/D:=%A>?(ED,C&#$,.:B6@>H'3H7"+7B>H!8A+/81$D1?&%!!$=7*<HF=B$&?%"-8.B;-6?'&>FE20.4>+</>A,:&?@3C21@G;C5*1.4H:@+=.A;)5#C-0B2==7E%:B>>>0;F*(9BF*$7@C4.64/@?;;/&/"FF726)0"A3G0B0>8H#G93>E%D,:+=G:4C2.=@55<FG/F?2,A2?CC&H.&#<G2?A;1>"-2-*H,(<;E?3>1=.+"@.B#-?39*B?(B5?;#<G%
@r8596
NTGTGGACTGGCCGTCAGGTACCCGTACTGTCACCGTGACCGATGACCATCCTTTTGATCGCCAGATAGT
+
-2D88;=72F%?)-"-DD2'6E1*/83++5%*D!-#,8%':%94G?2E#EAA!./=E0G4(D!DG$2H&7
@r8597
TGTCACGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGCAGNCAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGGCGTGAGTTTCCTGCTCCG
+
6*D7?-<E)E/9H<+*G<D=6=0<E,,*6CD/"#8D-A:6/73;")?#H?6?G6G>9'>)!H*'A<5-*A('8,(>9D7&$:%B%%)45?06"E/><5'6B4DC5&.DD1.9"EE;F)2B
@r8598
CACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGTAATCGCAGGCCTTTTTATTTGGGGGAGAGGGAAGTCATGAAAAAACTAACCTTTGAAATTCGATCTCCAGCACATCAGCAAAACGCTATNCACGCAGTACAGCAAATCCTTCCAGACCCAACCAANCCAATCG
+
@9?7G2*BEG?A(B=-C.3B>*<(GB'"7:,4/HEE4B4<7%@2-5&/-3F(B:>=*,'.1BG1FD65&61B!!70G!0=@G2@HCG-(EG>-:0!!1/897?#F"6"@!";/)F8C:@?B,2%3(+1A8B/#(-?E,BH9:!AA=19?'H+9/*1GD*5%8D..)!9DE6<A.5'(>?%D*-?"$>@56&(>>0;E";607B0"=,>))008.,=>D23:H&'A3;3EC28+>,#;;,E43*;@HB$H
@r8599
CTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATTGATAGCCACGGACTTCGTAGNCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATTCACTACAGTTATGGCGCACAGGTATGCANGCTGGGTGTGGGGAAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTANTGGTTATTCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCANT
+
(1#A!H4+;/'301"!-0E#3G"24C#%3<E>7-A10&/8$)'>#C&<GC)4&<C*G'+C$3.)<-:27'C"23;/H'?9H/C3A/>'+H:HHDC6<24A0A73&:7%?:D(A8,1@'0<(/315)&E':@:=AH?@>145,4H:A19H:'C/10EA*7!E9B9.E8H$,"$%(B!3;3G7+CE15C#-$"H*('C*@2H*:>H,0GH9;>;:-/,?02BBAB6#:>D,4#:3AFD5E'$B"9H"-?HE+9A4
@r8600
NCAATGCTGAGATAGCTGAAGAGATGGCATATTGCTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTANGCGGAACAGAATCATGCCTGGTGTTTACATAGTAATAATTCCTTACGTTATCGTAAGC
+
#C<1C06D),5A9"*'#0"+7"8951G7!03<G!>@6A4;"#318B8AFH=*=38A7%3$>20=%19=%F9#3&(6=F6H.D*03(:#G'=6H+6!-/#'3/;&#1''7%@;4&#<8)90/<D)/*F-?;;6?/.>?:!<*;'%=C/7AH*%8H8E3('H461=/.5.E>,)7CD1
@r8601
NNNANCANCACGTCTGNNACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGAGCGGAACNCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCGAGATTGCGAACACCGCTNTTGTACTGGCCGCGATTGCAGATGTTATCGACGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGCGCTCGGGAATGNTCCNGATTTTGCTACCACCATAACTAACGCGCTTGCGGGTAAACAACCGAAGAATGCGACACTGACGGCGCT
+
"$!$*'*'"**)((&&("'%$*'%"+"'&*!"#!*%*')+'$)$&((""*)(!"&&$&+)!"&!'!&!*'$!'+(")!&!$+"!*$'+'''"%$$#"%($)("!"#%#)$'&'"%&!$%(*'$$!("'%**&)%'*$$*%)*'*!%+(#%"$+$"#$"#!))!))%&+++"(+!**!#$"!%%$*")&'($()%+)*)+''"++''%)""#)!)$'*%!**!'+)%$*#$('"##%!#%!#&*'!&&%*'#)))((#&'"("*&)%#%+!#!*$+''%'#$'*"!'$#")%+)*($'$*#$(&"!&$&#+*&+)"$$+%%$(!&%
@r8602
CACCGACCATCTATGACTGTACGCCACTGTCNCTAGGACTGCTATGTGCCGGAGCGGACATTACAAACGTCCTTCTCGGTGCATGCCATTGTTGCCAATGACCTG
+
B7,.>0761*$2!>#DE%F<F"D*!3G)+&BH>9+CF#@DA%;?(3@0:9-%/(/4;1&546%DG.7+,9%;6-EEH&.A(94?7(-2C4'5:)6%(G6$E&562
@r8603
CGGTTAAAATATTACTTCAAATCTTNCTGTATGAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGNTTGTATTTCCCTCCAGAANGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTANGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCAGACCAGATTGAAACGATAAAAACGATAATGCAAACTACGCGCCATCGTATCACATGGAAGGTTTTACCAATGGCTC
+
@$/AC71D).3<E<-6C5<"H8'9(!B3+C//')8&>(7G<.%8C.?'&'H7"H<;AC7;888&GD=*6@,6#,)<!A87105E<%@/A&,@>G'F"(H1@C(D($7D'-/2G/%+$%1FDG!AH%E2E@7D(4*8E7-;A=4+CB2C<4E0-"*B<?0(/&4=-+(F2$7'5<+7#%#$,(.%*.(!1D#A/7";>3*%?@FA@8HE%;8=+98E;'?39BF4;475C1.82.2!C&*)C8!C#D'D?2*/9(*G=(>-
@r8604
AGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCC
+
HEG?)5),1B!?!%C77).F(<-!FH,,>$=<,A0?DD874/&0;&0A5(='E+(G'+/2%@,%G*%GHG>4')5*0)01<"?<03@E*F9.9(F$'
@r8605
TTGGGATGGCAATTTTTACGCCTGTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCATAAATCACCAACTCGTTGCCCGGTAACAACAGCCAGTTCCAGTGCNAGTCTGAGCCAACATGGTGATGATTCTGCTGCTTGATAAATTTTCAGNTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCNAGTGGCAGCGACATGGT
+
-G;"-/((0"@1HGD,<G=@)):D9!DA*"4F,%/$2F0"%.9<)C=9C37H?+:BD7!/@@2?#)?5EC?)F8,*/,#+28-@"/F5/4=%-"'623;)2/>#E/-'0>0-11@2(7>9<+4>)827&,2B24#4($%3"#34)!E'B8%47>&:91)B84#'&*/DD(F:(4==7C77!<9;"B0'(9(5?.B58+#&H@@,/!FC+055-#3<&AH7/!C!'&21##C!;71
@r8606
GAACCATGTATATGATCGTTATCTGGGTTNGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAATGAGAGAATCGGTATTC
+
%2H(2CB%1.9;B:&.EC26*4:G=*C=!3AA*"G%+,35%E5793!B92?E!)8#/@:G2F&@.@D"5C9C>+2BH,#E2"&59!'(1%
@r8607
GGCAAATATGAGCCANCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGG
+
0*3';$F3)B2+*77,F&"<33F'3-*62>=@4:*=.E-145'+2E+H#6#CD&7
@r8608
CATGAAGCGTTTCACTAATGGGCGTGGNTTCTGGTGCCTGGGCGGTAAAGCGGCAAAA
+
+3%>H$:;)@/FG!?<9&-#"3,6F>H=?*"3-"))$:0/+6()@H64%0;2)G,*+3
@r8609
TGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGTACCATTCAGAACTGGCAGGAACAGG
+
*$4>;CH%E!*A+-7"G9%2+"?F"0$#9$1&,%>2-669-7B7+B-"H7,/";=H@':=-%/4BFG(E@)E0B0
@r8610
ATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCAT
+
92!<>0-@'!#@H8#A:!A5D&">//&(0(;*/1)#*5-5):###=*8-@H=='147F".E5012#=<G)F.
@r8611
NNCGNGTANTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGNC
+
)!)%%"#&)*%+!!$('!$&#%"*!'%&'*+(!)%'$#%$%'&$#*")
@r8612
NANANNTCNGAATNNCNTNCNNGNNCCTTGCNGTNTAGANCNNATNGNGNNCNNNCGCNNNGNG
+
#$"#!$!!""!#""!!!$"#"#!!!$#$!!"!##!$#$#!!!#$$"#!$!$"$$##"!"#""$$
@r8613
CGCNTTTGTATTCNGCACTGNTGAGATAAACGGCAACTGCCGGAAANTCCGCCTCATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATNCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGTTTCATCGCTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGT
+
&)$)&")"&%'&#%)'''!%%+"+!*+"#'&#&)%$)%$(#)!'!+$&+*'*$"!&"*"+#*%+(*$*$#%!'&(!+'"%#&)))%%&+$*+$##"(*$%'(##!$+((*+(!"(!+$+*#)()%%"%%)+"+&*)'%'"!)+#()$%%&'$+"!*+$*'"+'*%(*##"($%(#%!$"+%%!*&%%!*"%(#*+!!(+*(*%+#"&!)%%)+(%&&&!&)%')(+(%)!"$++!&"!)%&$*%+)#$#'&'+')(!#(*$)!%!('")%%)(+!'&$#"(*&&%*'#$*"%+#)'$(*#
@r8614
CGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGC
+
F9.09CF:AD;/5>H/)5G.7F3@/+.+(!2'*C:C)3%)'6
@r8615
GCGTATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAG
+
B/5H?/9>F>-;<$"HBF?*!&B-#0)=&63:73@B)7.'%62#4?=*>FD:B#40=*5>@-0.3#7:1#A%8
@r8616
CNATAATNNNNGNCGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTA
+
%")%$'(&%'!*!!+%&*!+!%!'((&$!#"#'&"$*(("!$&!*+*(&&&$'+$"$$++%)('*"!+)")#)&+&"#''()$(+**+'%!*(#*+%#$$&)#
@r8617
ACGCCNGTGCTGGAAACTGAGGGGAATACAAACATATCCGGTGTCACGGAGGTGTTCCGGGCT
+
)'%(+)"##$"(+$*++&''##'**$"!*$'##''+"(#+*!''+!('+'&(&&(%%%##"#&
@r8618
GCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCAGATTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTATCTTGGTACGGCGCTGTACTGGATAGCCGCCAGTATCA
+
73*E7-G0'<@/7+?,!C??*483.>45=<>A(32%5;57A-=#<5*$;?=5?F9?%1&A#8D+2-1(:(>,*+C;"-#.4A>%"?9)21;B,73(4?##$)&G#'F2/=*'1>!-=-*G2:AG6@@2B(+E1H6!A?G2@$!*6.&/=262<.*$,F04:B5,',%@-0H3>*)5*?"GF18=.8!
@r8619
GGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGT
+
=!&56)$E&9;!))!3,!!=&@1%97?2+H,9*!6:;(&,4<?+*,,%)&+?&43%C
@r8620
CAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCANTATCAGGCANCTTTGTTGTTCT
+
H)*8#?<-5!F9*14@,"?-7E3$8"*&#8B2?H&!3B,29*"351D5H8;/'>)/04:G.(-/./!>A;;%3;F=A9B
@r8621
GATGGATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTNANAAAGAACTTCCTGTCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCT
+
?6"/@2=A;>=.=1$</B#B#E>3)E+@66#H>;2/./8(+**'+$=@;>,21%$!4$+A<?%C9#9116!-+H1&!#/</7*G"#-8G<<1E."<<7F15:HB,)7=+643))2'<0'A<4B<)
@r8622
TNNCCTGAAGAGACGTATGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCANC
+
)("'$+++(%'$*()+"''&$*!+'(##""*#!'("%'(+''&!*!#!&#))$*#(+#&('$()!$$('$+#"'!"%!##'
@r8623
CCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGT
+
BB)11+@CF+$84F98>&-)6<3?:)H5!'9E.GFB8&<(>3.#)/1128%%0D/1DF
@r8624
TTATGACGAAGAAGAACGGAAACGCCTTAAACCGGTANATTTTCATAAATAGCGAAAACCCGCGAGGTC
+
@9C)5!60-<5.H)!:"A7)%AE-65?%>A9-F,A"$B1<.1+-;8=A.EA;>)#:AH,>;6?.867"<
@r8625
GTTCTGTTTACCAAGTTCTCTGGCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACNATGCA
+
><@9)<$:03?1@*@91))C1;!65=BC=D570,C4%0?3,>?9!D=F;EH2-&F)<!(>%@:@25E.D)?'05(*C9B.273EBD.F%'"6-F,4;:B?$E.3-@7=9,?
@r8626
CCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGC
+
D;33-F6=C!$8-5@/4C8$F<F?**AC>;$6#*)!F%=/)5".>04%",E"=5>*A
@r8627
NCGCTCCATAAATGACCAAACGGCCCGCAGGCGGTTTCACATAAAACATTTTGCATCAGCGACCAATCACCACAACC
+
"3<74B'*E$EG#575:'A:02:/$G;0$6B$3?<$?2070%9*$/&BHE3D.."E<!%,0,/+2B@-8-B;70"4%
@r8628
ATGGCCATACATCCCCCTTTCAGCGGCGACGGTTAACGGCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACNACTTCCGCCATCATCCGGCGAAACC
+
8>669&"/:=./5!F-895=EA-?"@%A5!1=:G2;*,=-+'<1=7-,<4",<159/"3<5:=,&6(H($@E4+E#+>73<.*518&&,'B!=6CE-=
@r8629
GTTTTCGTCGCCAAATCCGTACCGGATGCACTGGCACTGTGGGTGTGCGACTTNATTCCATCCTGTTCCTG
+
?15A0226)017#@*!*C7B6/)-A=788D,4<<@:($;)$?=!3B1/;670:+C>/-3D&7%C,D*=G(#
@r8630
GNTNGTCGCTANTCGCTGGGNGAACAACTGAACCGNGATGTCAGC
+
#""$**&#$"')+#)'(&*)$+*&%)$"#(!$&&&"#(%'*))("
@r8631
TCCGGTGTCTTGTCTCCATGCAGACATCACGAAGGTGTTT
+
5-"H&3<)/5!'=C;:4;,F60:E/<5FG;5+"B>./*A,
@r8632
TGATTTGAGTTTTGGGTTTAGCGTGACAAGTTTGCGAGGGTGATCGGAGTAATCAGTAAATAGCTCTCCGCCTACAATGACGT
+
@?CAB+0H,8&G&2BG@%,#4.DB'&(;3?,:,G&0C:>4?)$A"($<A2?>@B=/1+DE?8H90F=>5757.+?235"C5D9
@r8633
AAGGCCATCTCTCAGCGCCTCTGAACAAGNTCACCAATGCTGAGANAGCTGAAGAGATGGCATATTGCTACGCAA
+
-2@B6;BH3*E@B);60=E)G96$GG?C9BH8)EH@$D<HGBFE98*0(FA4!@9D?!!A$E3#-E;?@.5;!B&
@r8634
AGCNCNGTAGACNAAATNTACCCNTGGCAATGCCCGCGCAGACGATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATNACATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGNGGATGAAGCCCGTGCCTTTTCCCGCGANGTTGAAGCGGCATGGNAAGAGTTTGCCGAGGATGACTGCTGCTGCATTGACGTTGAGCGA
+
&)')&&$("'"("))"'$+$("!&%*&'"%($!)''$&*%((*(*%*'%!'%'(%"("!!%!"%%%#"##$'"**#&$$"**$'##++'%%&)(%!++%()!)(!#(*+!!&$'&+""$!*')'&##%%")++$*(%&*#'(!+))'%+&!+*+('%$*&'''&#'()"+"!&'("%%(+##%&'%%(%*$+!+(%(+)#)*)"&''$)%%'$*)$#(+"&+"&(*!!&+""')#%$#!%+%)*$"*&*!
@r8635
TCAGGTGGCCCAATCTCTTCACCGGTTGACGAAAACCAGAGAATGCC
+
BD/C5-F<62=210"@A+B2AG9:2G="1%"0!8+.F*4@6$"F%5?
@r8636
NGCNTTNNGTNGGATTCCATTGTTNATTCCACGGACAAAAACAGAGAAAGGAAACGACAGAGGCCAAAAAGCCTCGCTTTCAGCACCTGTCGTTTCCTTTCTTTTCAGAGGGTATTTTAAATNAAAACATTAAGNTATGACGAAGAAGAACGGAAACGCCTTAAACCGGAAAATTTTCATAAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGGGGCGCAGCCGGA
+
"'*&(#!"%*!*%!$+*%$*#)!%&*)#*'%!&$*(&"&)!+*++$$*"&)!&%)+*"(%"*)#"#!#!'(%&('#*#()!)*'*%#$'$*%%)"$(#%&(!*#"#'%""##%+%'%+&*+&&!'")"&##"#%#('*()'(%$#&")#")+%$&'"!+%%(')#"!$)%('+(&"+$+%(&!'!$&(+()"(%*+!&'%'#&*##!)+!%*($))%!'!*)(!%%("!+)%%')(++&)'*!!"!%!$
@r8637
TGTTGAGTCTNCTGCTCAGCCTTCTTTCGGGCGGCTTCAAGCGCAAGACGGGCCTTTTCACTCATCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAA
+
<G?C0%*F:2*-3G44%44D43E9F3?0H*12H5"2>>8!F&*)G<$AF+H*)H*$GC6D#@(?HD&+,176FD4B4E?900/@&8C#-+(2D,9:)/0"%@>4'B3?*57,B851>&*F?F>(6HD.,0<-3,,356:'H6(8>6%$>&9!FF;@962AD
@r8638
TAGCCCACCCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTCTTAACCATGTCAAACATCCACTC
+
*G/#5:D8E3:6<@FF5>89))1,<-*A(8-!96<)*:<4$DA<%"CD;4?')(.9=(81'B3#%%6C3/
@r8639
AATAAAAAACGCACTACATAATACTGTNAAACACAACATANGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTCACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGT
+
%F#3-29-'"0?1;CBA&D8*.?8>%=56B!>73B:'==<50AE;$$G8==<9*"8(.!,DB9H?%##*%+87B,=1@4/3#";3@&"=.<FC-""C;=*@,*#$FF$:23A.3AD9+305)H<=3.=C/!D<.C2)4-:,A@0'>16/,H:F/&9@#-8-+(;3%+.;0$+E$:*7F)&4"8C
@r8640
CTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGCAGTCGGCC
+
B9DC10B(!:B64)==0)-F6:88<74F0+#8"DG8BE2<A#2F0!-,&2(0%!:G47*<6?:2F,FA12;C'?B"+D)"C6D<1%F#B<-"C;1G7,BG@4(0$<"<:271/4?G(6%6>8,H<,FC72@!.G=#?#!"91&,G>64%,1,C=&4<>E4<3<68?ABF#<6>)**C
@r8641
TNCNNNTGCGNCAGCCGGACCGCTATAACCGCACTCGTCACCGCGATAGGTCGAGGTGCAGGTGTTGGCCAGCATGA
+
&"'%(%"##''+'*#*+#)+!#(*"&)&#)$*)#&&*&&*#%&*%#('*""$#"'"!*#!+(%'(&#+)+#'(*+!#
@r8642
ACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAA
+
B$&>!:2H3",B8H75+BE9!1),%;4CFF0:53?*=E<#'><F:%%8!B(7DH7.;2+>9',83,GE:),#D5&3B+>2.=-+?!4?/.2408GG(7@A89;;.3#1
@r8643
CCGCCCAGGCGGGCGGTTTAAGACCGGCTGCACGGCGCTCCATCGTTTCACGGACCTGCT
+
HC7AG9B=!+G&C<2AA*!.FABA)G/-,15$+A$C05C/F#/F!H%.=+%@)6+%H.?5
@r8644
GACCCTCAAATTGGGGGATTGCTATCCCTCAAAACAGGGGGACACAAAAGACACTATTACAAAAGAACAAAGAAAAGATTATTCG
+
(#-.%:-*-.'4B(AC..:>-'(9=;"(#1H?1B"7")>1=,F6?4>?2!EG?@D=<C"D?,-E::#/1;,645!618-9477"B
@r8645
GGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTCGGCNTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTTTATCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGNATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATCCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGA
+
"A1/?F<%2)B>;1$<1/DBG*1*8C3(&-2C:E1)C95F(#D3(?1<'<,7*2;@$;,(2<*;161#+4>+36%"'A*>C!)9D?9A)%BHD66:)5H:A0'<=,!*9@+A?DC':24?;E?C6/0;9F'";#6#AD0.3G<&$*A!0*2E)B5586?*!C3<?*1BA>(9.@C(0$5@81":AD9/+,7..)82<@$/!3;+-F1$+D?"G!,HH$-GH'73<?6'#)F!*21="%5?.'@22D"-F>:8H+@F,0!2.("'6<<.6CG+"7&%0A#H$*=)+<;52+3C-7E&$H:D?"'D+/"EC1;.,2,)B&>%F:8+@-<G2/>
@r8646
CCTGAAGTGTCAAGTACATCGCAAAGTCTCCGCAATTACANGCANGAAAAAACCGCCATCAGG
+
G/(F+)+0A61DE-:2.43!1G&5',(@E("2,9$<0E:<6$,?/B:!53)B;4H/E?5)&?0
@r8647
TCAGCGGCGACGGTTAACGNCAGGCGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGNGACGGGCTGGAGCCTTCAACGCGCACGCCCTG
+
@:)@)C"C5="=<!+2CC3%,).8FDFFHC%,3-@D#C<(FH3:9)/81>*<G$='$#!?H:!*99$(,;"'4:,'6D*0F40C-4?!=21/1;)&5C3"@4345'A7#BG>%$?BB%8B/7+8A8%?2/<38?&%2/)*3>A-=@7:G!)BA:+(!+&1A$=1.902ED',F)8+:4..&,.7:"!)4':%A=<
@r8648
GCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATTTCCAGCTTTTGTGAAAGGGATGCGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAAC
+
%H*%572-03/H$CF0807$,C8"8)+?811-<27%1?FH/7'.>7*@:1#+AB,BDE-&C@$691($AG,EF5ED):.!.6A*;4F,G39<>0")1C@!3%2=9:*)<2<5&#0B5+?+4"C>A=A9!)F;)#947A4D:*/(=,
@r8649
AGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGAGATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTT
+
G-E-26%G8$=64;,%1!4D!@D05$!">8-)<G@,='><#<"1)83+7/>6":E#">.+*&:".-!%<*G.98=H&E;>,$2-&-37!<,?@1E)7??:H3:5$>#A+G9,>@05=41#)!68C@-?5?9;;B'.4";,8>C=
@r8650
CGGAGCCACAGACCGCCGTTGAATGGGCGGATGCTAANTACTATCTCCCGAAAGAATCCGCATACCAGGAAGGGCACTGGGAAAAACTNCCCNTTCAGCGGGCCATCATGAATGCGATGGGCAGCGACTACATCCGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTT
+
+"&!!!&!'#$()%+%'$(&'$+$+*!('$#(("+!()"&+&**!($+&'&("%'""$'"%'#(($"!*+"!)+!*"%#!%$"&'+$+)"'$)!'')&$"%)!*+'$'"('"$!#"!("!&%"%)"*((!)+)!&$#"+!&$$(*'"''*"%#!"$!)(%**#)#'!(%&%
@r8651
TTATTTATCGAAAACGGACAGTCAGGGCAGCCACAGTCACTCATTGTCCGGTACAGCCGTGAGTGCCGGTGCACAT
+
A!&CHB1:0/D9399F3D"9:A;"8D;:2'CD==F;0&.0H."@"#FG55&*@0C!4.?='AH5;%/0(&2*+F"@
@r8652
GGCCATACTACTAAATCCTGAATAGCTTTAAGAAGGTTATGTTTAAAACCATCGCTTAATTTGCTGAGATTAACATAGTAGTCAATGCTTTCACCTAAGGAAAAAAACATCTCAGGGAGTTGACTGAATTTTTTATCTAT
+
2%"-$D5#?B(A6/3(7;1"(C5841A$:&5,$"32(*0B;HE!EB7C<E'B+'@1?(?)E>B&?=H>%F%78=(27/'/('$17C:C07&*3G1.'A@'1;/+5F3@=4G>4/;A)08"/<E7(.(*54A9H5'+:C*9
@r8653
TCTGCAAACGCAGCAAACTCACCATTACCGGATACAACCGGAATGTTGACCTTGCCTGCAGCAACTCCGTTCACGGTGATGGTCATACCACTGNCCGACACGGTGGCTTTTGTTTTATCCGCAGACACCGCACGAAAGCTCTTGTCGGTTACGCCCTC
+
+$"&&+(%'%$*#'())*+((%"'#()$+!#'$(%")#(!')"#")#!+)()$+$#%!*%("!)*$*"&%(##$(#)++&%&&)+((#!&(&+&!#+$"$'$#(('''!%)$%"&+#')"&(*$$#"#!%"$#!%)&#))('*"%(+&$**%'+%$+*
@r8654
AATCAAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACA
+
8F%A-3:&-4$.7E<99"A3$H<A0!3!0@;.'?8%*8+@4-HC>$87
@r8655
CTGGAAGACCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAANTGGTCGTCGCGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCNGAGCAGT
+
:916GB./G*3D8H385)$$!=>0@D/*',B@")!G>C*7,(A07C/!=E"E*5-3:)&95$AHD4#/=,6&0$!>E$H-5:3C2::)>H-7;'&592*>">58DC8*A748.*!9=?"CE@>=BA)54=01<D7'&'/5@AB33'=$%EC4:)HE3B5D6HD5:H:.82F%9"+3E?B>A?A11C=G.E6?2""G1/
@r8656
GGTTCACACGGACACACCATCACCGTTAACGCTGCGGGTAACGCGGAAAANACCGTCAAAAACATTGCATTTAACTATATTGT
+
;*A!A?$)>?A=)F/C/&5!+.,4-'1!7CH+:33*$9-D@-&=/GAC?+C*'9H>&!FG68=E:;4+B.3#7A(!):6<B8/
@r8657
NNTCATTCANCCNATTCAGTGCGTCAGGTGACGCGTCGATAACATCTGCAATCGCGGNCAGTACAAAAGCGGTGTTCGCAATCTGGNTATTGTTTGTTCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGAC
+
%#*!&)(#&!((#(+#&)()#)!'*"(#+'))"&)+!!&*!+)"++!()!'$%$)*(+"++(+$"'*#&)%&$&%##$#$)))+#%'+#(!*+'$&'(#)&#'+'#&'#$&##!'')+(##%"+&("%%)!#"%*"'#!#&)$(
@r8658
AACAGACGAAGAGTNTCATACGTTAGCCGCATCCCTTTCACAAAAGCTGGAAATAATGGTGGCGAAAGCAGAAGCAGATGAGAGAAACCAGGTATGACNACCACGGAATGCATTTTTCTGGCAGCGGGCTTCATATTCTGTGTGCTTATGCTTGCCG
+
D-@>C-:)E/?14?E8%;)+(H63=D<7;2->#B:A+!)'"65H>=='(=<0?02CF'*F+.$&'%65"G681*CH5(0C,246?AG5%,*@A;;5@AG!.H+BE*D;$3"#;*D76!?$<)(.+(2+C?0*2@6>;/2,BA%=C?H-?"8"*"94=
@r8659
ANCNTNCCCNGANNTNNNNNTGNCTTGANNCGCNAGNNGTNNATCGCGNTNCAGCCNNNNNAAN
+
!""!#!"$$""!#$!$##!!$"$#$$!$#$!#$"$#!!$"!"##!"!$"#!#"!"##"!$##$"
@r8660
GATGCCATTAAATAAAGCACCAACGCCTGACTGCCCCATCCCCATCTTGTCTGCNACAGATTCCTGGGATAAGCCAAGTTCATTTTTCTTTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGNTGCTCTNGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTA
+
41*,B@H<=+#)5G6</)<!!<+;6B!'$*48@@0HD/20G/?&"?E+F;A6&B;166EBE8"6HEA-:=A-&A#8+&2)7",#8$+H*B5?>3.A-B7B@1"(CF(@E%7F"!4E0C#).*E#:0=G%@$/"?/.+!H(A6#$:A.!G&7%E9"$0!F!5F@18."&*44
@r8661
CATCGNTTTATTACCATCCTCAGTTGATGCTGCAGCGCATAGCCCAGCTCTTTCGGAAGACGTTCACGCCGTATCCGCTCAATATTTTGTTTAAACGCCGTGGTACAGCGGCACCGCCATCGGGATTTTCACCACATCAATGGGGTAACGGTTTTTCCCAGCCACACACTGCATGACATGCCACCGGCCATTTTTCAGTTGCTG
+
7*=D2'+-3@EH,957A7-H7CD'17*?"HB/,##B)@?#D#?G6@E0-42<<#)"!D(GDF>0/2?C$<H/"87"+(5#8&:$A+1:&>B=#:BD524<1,#5?6'H788!0#3/"+:!?.<5A5,+:#B/A3!2?>A31,4+<F0;*CE'!4>8G7E%$B0%0<>9BC!/)9H18?9?&E'::/-1>F70D:ED)(C$D5<E
@r8662
GCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCNTAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACGCCAAAAAATATATTTATCTGC
+
H8=2#;*8?;G4%@5B*#>'#&)2<#G8*&65F/3!=1+6:E*)0.D>>&%)"C7&(;4.568>'E67-(A%!@7BH-3EH*H&-+$!8HH/'8.6
@r8663
NAAAATATCTTGANANTGTGCCGGATGAAATCGGTTCGCGACNAGTAGA
+
$:2F3-,">":&7!((;EB#+)/6:,?;84A?5)"/HBG5G#0(D2'9'
@r8664
CCGGANGCTGGTGCGCACCAATACCAACTGTATGCGCATGTGCACCGGCACTCACGGCTGTACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTAACTGTGGATAAACTTCCTGTAATG
+
!'$(&#')(+!%)!'"%'*')!"$#+"$"!+(&'!("!*&!""!#%(&(!"+$("%%!#*"'$)!%#)(&)!&+%!%+&+)$*(*)*$(+#!&!+*#"!*+!&*)#")&$*')&*%+%#$$%("($$&)&*""$!#!&$"%('$%**""$++*#'(&%''#"'+
@r8665
ACCAAAAAAGCCAGTGATTCTGCATTCTGGCTTGAGGTTGAAGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTT
+
41</F?$)**68A)78*1->5!)=379#6=>890@?!1%5?@&",4;8/815F"%A9B'H;8>@"&8/*D7$@D<0?%81.*3
@r8666
CTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACC
+
<2:BBF7=#-;D<3'.0>D#F7"?3=<,D,-0E8H%;/,C
@r8667
CNNAGCTATATGCNATCTCTTCAGCTATCTCAGCATTGGTGACCTTGTTCAGAGGCGCTGAGAGATCGCCTTTT
+
'$!&*)'%+%!('%)#!(+'#')*%!#%'*$"')&"!&+(*'+&++$$(')$"!"*)'$%+$+$*&()*&!&$%
@r8668
CCGGACAGGCTGCATCGTCAGCTCAGTAAGCGTCCTCCGGCGCAGAAGCGGCATCAGCAAAGGCCACTGAAGCGGAAAAAAGTGCCGCAGCCGCAGAGTCCTCAAAAAACGCGGCGGCCACCAGTGCCGGTGCGGCGAAAACGTCAGAAACGAATGCTGCAGCGTCACAACAATNAGCCGCCACGTCTGCCTCCACCGCGGCCACGAAAGCGTCAGAGGCCGCCACTTCAGCACGAGATGCGCTGG
+
FA-/"C#3;H93&-C)<9+='>"&D0D/#,.!6759(!$&-B.=1CG3?<.1$6!)H;!3:)>@*%8#?9HH/.>E/;>B;.*7/97)84D(;-0)';$1@C$F5C,,C95?+A$8@%$/3?&?'/AG%.A/7E?+$?:$*>B83+;.'@)@78??(A-@C,$8A"#%(7$4F.;4)>5613@?D-B9E0(7-+=B!)E<-C22+CC0$=)E)!6%;"1)/>!9*C=0.G0H+9):G?)*2>-C/G
@r8669
CGGGTCAGTATGCTGCGTGTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACCGATGCAGGATATCCGGCAGGAAACACTGCATGAATGCACCCGTGCGGAGCAGTCGGCCAGCGTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTT
+
@F;,B55"<<)=@4$$1/!80$5GA<&.2(G87H@+@(85,5G<'H#&;".@92G>%G=G$5.@!B9G!@%/7DE5(A>:0!4#%&?55,,&&HEC:'A'>$<8.(-!2027%6*-3#B::9<:2:<8;6-<D8+;DGF"@&77H08-A8.21E=-.7"?5A
@r8670
GATGTCGTCTGCTTNCTTATACNCAGCCTCTGCCTTAATCAGCATCTCCTGCGCG
+
D+7B:'$H@;.);%//=>?!*>4D%*+7),$4*'!!5&?F&5%-E5BBC%'7C"F
@r8671
TCGACATCATTACGCATCGCTATTACGGGGTTGGAGGTCAATGGGTTCAGGATGCAGGTGAGTATCTGCATATGATGTCTGACGCTGGCATTCGCATCAAAGGAGAGTGAGATCGGTTTTGTAANAGATAACGCTTGTCAAAATGCTGAATTTCGCGTCGTCNTCACAGCGATGCCAGAATCTGTAGTGTCAGATGATGACCGTACTCAAAAATCGGGTTGAGTATTATCTTACTGTTTC
+
9H#067F??7,+!383>4>H54,('F(!&G,HF"3("@/C-:,.&F58#;!B3EEB#5DF=9>3=,5,"%;+0:8,'42!%6%)0E-'H65)B39@CF'0<"@/,#-1F4.%45-%:-2.B5.8-C60D#@78?A20F'4>D>E'A8#A:F)(,#,*:+H"/(A1,-*$E(9DA@".<6'1G!#<2"7#"+,*&E@&HE?0@>1G"3;3-"@E)1%0+7<C7D"?*?4;G<G7#$#:(E;
@r8672
TATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTGTTCG
+
DCC#12E,-)?;9/5$0*(";)?.'B==&C65/;;=*(G%!
@r8673
TGCGGCGGTCAGGTCTTCTGCTGTCCNCCACTTGCTGCCGCTCTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCA
+
*B/-+H<E,!*.,*/-=-'8(-$,12"0;.A=8E&;C:G/)B)A5'/0=;<<+>6A1=E'2(,'C?,1'@46GB,9@(,8!BHED!)=B9.E-:%$(
@r8674
AACCGGAATGTTGACCTTGCCTGCAGCAACGCCGTTCACGGTGATGGTCAAACCACNGACCGACNCGGTGGCTTTTGTTTTATCCGCA
+
0*HD=HE8E74&:&-5:H02-":':-2$24!#3?=(!)DH@,,@.C3G'90=7:<A%#5BF+++<=#G"C-7C7944AF1A!?@?4A?
@r8675
ATGACAGGTAAACGGGTGGCAACAGTACAGAAAGACGGACGAAGGGTGGAGTTTACGGCCACTT
+
H1'3D-?7@G#G'$%/,>4,%7?8&4D:862-H+-$9!%)+E6#'D.;!;":.G*;2$H")E+7
@r8676
TAANCTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTCCGGCAAAGTTA
+
:<+'(=-56H3=A"*G:#.B$6%.GD&"'0F,!'CHC16G3759>-8&"9A-+F,*.BG6,9G;D%E")1@*<=0;,/G3!/*?1?C,&;C@4D08/:./"GB,010B=#7,*
@r8677
NCAGGNTNTNGCCNNACCCCGNNGGCGGCATGNTNNNGANGNNAAGCTGGCCTGCAAG
+
$#&)"!#!%"(%%##"*!"*''#(&('!*!!$$*"%#&)$"!+)&+!%#+&#$!$"&$
@r8678
AAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACC
+
<!D+#7*')1>+@56<(?7$.$##CG>+C:@3=@B/')-)2:0C?58)EAB5E4C0
@r8679
GGNNAGTAGNNGANNAGTTNNNANNTNNTANACATNNCNTAGCGCANTANNNNNNNGNCNTGTACNGNNNNNNCANTNNTTNNACGTNNGAGANCGGANNCGANNATNN
+
"#!"""!!"##"$###!""$!##!!"!##$"$#"#"!"!$#$!"$$###"$"#$!!#!"#"$"!##""!#$!"$!#""##!!$$"$!""#!!##!$"##$!#$$$$$$$
@r8680
GGAACAACGCATAACCCTGAAAGATTATGCAATGCGCTTTGGGC
+
0:F-.D7-AC/7>$2'!,B825>G6'@6B2$H."@'&>%?,3F%
@r8681
TCAGGACATNGTACGAGCTAAAAGATTCGATACCGGCTCTTGT
+
/)@:!6#(A@!BE@6!6'(:41.B">.*33>":89,@E26/HD
@r8682
CATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATGGTGAACTCACGCGCCGGATCGCCGGTGGTCACCCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATGCCTTCGCGCTGTGCGTCCGCATCCTGAATGCAGCCATAGGTGCGCAGACCGCGTGC
+
>,6&<5)HD*9,=4?6+??A?6B2?-2EGB2=.6-"B363G0=#.;8#;&.=>*+"4'D14,BH0C4-#2@%:/5H)&6F&!;")G)'7=:3,!0<-:,7(?BD*'=,#?//%@D82?6AE3+8#.H*G2#=72#-.AE=:(G9@A9.:%30@B:#5C@>84+C'=
@r8683
GNTATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTATTCCCGGATTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCACACAGGG
+
#"+"%!**(&&$'#"(*####(&&(*(#(+&#$+(#)##!"#)#$!&'%&*%"*(!!*!#"(%$"(####'!(")'!")%%&#($%%!!')))#&$+"$%+"%*'+#)(*($$&"&$##(+''$'&"
@r8684
TGAATCAGATCCACGGAGGGATCATCAGCNGATTGTTCTTTA
+
$:4""659C5CH)?8591.B&BH3BH0).:=8HH?>HC/)3#
@r8685
CCCGGATGGGAGTAAGCGTATTGCTAAANTGGAAAGCAACGAAGTCCGTGAAGACGAAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCAAGCACTGCACTGGTGACCTGGAAGAGTTTCTGCGGCAGTTAANCGAACAAGACCCGTTAGTAACTA
+
%+%+F$!<E0(3;35=!1E96$%9(>$.3G7>!3");,0%=@5++":*F:@D!8;(?8?,9H/""/:=HHH32(E=-=")03@62&)D;G@7/2F%6+!@,9>&2#.@'00E5E.6'%3+3EH@6/,A1'<F"<-31>&,;!G&;F:F6'4G7#!)9%:38#D(AF#.>G
@r8686
CGGATTCACTTCATGCTTCGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTCACCGGAAACAATCGGCG
+
;7E(G<G=>97.&FB:.(4*02*;DC"94@440E@9&7'#2D6D54#++('-)+0-G059:*B18:$#64/)8C'<1H5;DC<#7=4G4,22-<7
@r8687
ANCACAAACAGATTGAAAGCAACCTGCAACGTATTGAGCGC
+
(+(1*(6(F-<-1D08.B.<+%CA:421E&1<-%9A@>ADB
@r8688
CGGCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGACTCTGCATATCTTCCGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTACTGGTGCCTTTGCCATTCAGTTCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACNGGCTCACCTTTTTCGTTCTGCTCATTACA
+
1)@H'&C71G4?G8):+2,5CD=D@8*5'5$?7<!(3%%2+.B<2EHE)1%'H%;+</>AD#D1!3?(D,,B1$#*81+#;>#(BB17BDAAE%%)DH09=>3&5A5=/1.1.1#A:F,1&9;%E"6F&==+DB72D&$)8)6'F9?%#.)&"/4A1<B=1/C58'E=7+('H=.2+:-8<2D>(5(/G3!1G9H+2(&238)H+@E2$(9'*B=>.@>F)+$&$"'$#5%&5*FA476#275$/=7)6!7G2F.BA>*#&"
@r8689
TGAGCATAGAATTAACCGTCACCTCAAANGGTATAGTNAAATCACTGAATCCGGGGGCACTTTTTCTAT
+
'%!D"*!:.$*FA+-(4#-0(:?D%4BDG/0).E2?@&(!<%!%/51'7HB79$+E4<<G#&@/A:))-
@r8690
CCGCCGCAATGGCCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCAAAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATCAAGCTG
+
1/:+.'@#(.4HG7D0H#+D!'%E;4?-/'(4FF=)65-5&>)5@(."$!+B-G"9@>:F<"5H!2?')-G*:9C5?E'436;2%:47=EH7"@770*H;1,A:6%C7:+!:H'-6@C==22)*%5:9-+..?#>%&71<1%+G-8F5(7*#D)GF/2C=.<;)8%#:3'GC.7D2=74/F-GGG
@r8691
CTGCCGGAAAGGCGGAATTCTCACCGGCCCCAAGGTATGCAAGNA
+
0%,;'":%=6@*D5:#6+;<=E@"4.'(74$.@5!"?81G#A70B
@r8692
ATNNCNTAATCNNCNNANTGCACATTANCCTGAATGTTCNGTGATGCCTATTACT
+
*"!#&#&*!)*!'&(%'+')+$")"(&$*(#&'%)&#+)$(#"+"$$&()$%*#*
@r8693
NTANNCGGTTGNNNTNNGGTNGNNTNCAANNNNAATAANCGANTNGTANNNANNCTANANANNTNCNNTGCNNCGANCNGTTANATATAGCNNNNNGATTGNNGNNANNNATNAGNGATGNNCGNGANNGNTNGGNANNTATNCCNCACNTGGNNCACAAANNGNNTTNNCTCNNNCNATNNGANTNTNTNATTTTTTGNNGNNNCAAC
+
##$!!#$$!$"!#!$!!$$$$$#$#""#!!"#"##!!$"$"!$##$#$!###!!###!"$"!##"$!##!"""$"#!"!#"$$"!$$#!#"$#!#!$#"##"""!!#!!!$$#"$!$$!$$"$#"$$"$"###$#!"#!"##!"""$"##$$#!$$$####$"!!""$#!#"$#"!#$$!"!$#!$##$$"!##$"$$$"$!!!!!!"!
@r8694
GGNNTNCGNATNGCCNNTTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTNAACCATGCATTCCGATTGCAGCTTGCATCCATTG
+
"&(%$"*)"'""**)"!+''+*(*%!*'&#+)%+($()'#"&!)+&**&+)&$'$*)&("!)#'*'%%!+!(##(*%(*)""+#!&$('"*&#*#'&+)'(!
@r8695
AAAATACTGTGGGACAGCAAAAAGCGACGCAATGAGGCAC
+
H#"80H#>5-B1&#0*&*,>/*H9F6G&E8.@&,D$F?>9
@r8696
AGCTTTGGTGGTTTGTGGCAGTCGTAGTNCTGAACGAAAACCCCCCNCGATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTGAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTANGTCAACACCGCCAGAGATAATATATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTNTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTC
+
>(,6#:-:C@33H2/D%*35A"5=,6/5C:1'@0.4%"C"74=79=>;@%(A?EAB1=-/C"%CB.=/6B$&#,+GCH===,DEB:E7%=H.?;9A),1887#6'-6792):=,@!H755"G=&23-H(F#->(:?3EAC>BF)60)$$/59>F&0$2;E,.'2)23&95;94+9C3=H%4(D!@<$1>?4)9($6#E.?'@;&,=,)&;(9)5F7+#0-E;7B#C4G*=#7$")$,9:%;E'9<%2-<(793A82=F.@4!18EH1*AD-9!6":'>"B(>3'<-$8!::H#"@'46/2E)%.=<(+5'<.//C82%F$06+5'FA12$2CA?*#==/>E8.=$GFGE-?&-'G42-A9-CA,*D<19-BH@93,
@r8697
AGTCAACCACCAGGGAATAATCCTTCATATTATTATCGTGCTTCACCAACGCTGCCTCAATTNCTCTGAATGCTTCCAGAGACACCTTATGTTCTATACATGCAATTACAACATCAGGGTAACTCATAGAAATGGTGCTATTAAGCATATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTC
+
E(0>A0+F:0C280!918+:*%)17C<"=7*8;6#0C*'%%$.*'<&D115A/,"5+-6+("'H6*@?G-(3)D=G.#*'</.=--,9,H80.7C@&&E";5%H1+0E15%"9".;(9@#AD)7?@*($*G9F"2%71=86!!'>>$>$A6%@/#F9.1+881(5B6=7723!>B-?A;$-4#+*,=$?-F3G#AF
@r8698
TTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAA
+
G$>%.2/:&F.13C82GG./C9*1BA2-,4G-:$;8!B4<0:$*/-395!)!"3DH2$1"3'?9)@'0=72*EC=2:3//3'8)9AF4;1;2
@r8699
ATNGGNGTNNTTCNGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATCATCCGGCATCACCACATTACTGCGGTTATAGGTCCACGTCTTATCCGACGGTCGGTCCTGCACGAACGT
+
%&"*"'&)&!$!'%#+&*#!**(%)%*("!!%%'*+&!%*)%%$%(++*(!*'##*'##'!&*!(%%!'!&)%!%&+)$$**)#!+#"'(*#%'+"!)%()%)%)%'+$$(!++"+##+"!
@r8700
NNNNCTNCNTCCGNNGGGTGATCCCCATGTTCAGGGGGCTT
+
$%"$)(")!$*%#&$()'+$*'+")*'*&+%"#%!"%#%$+
@r8701
TGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGTCACNGTGGTGT
+
F-D&8050F*?D@AB/9H:1F@,&DA!C3>,379G#'"7G?,B&,7*'H-7"9'%0A@7E7.<?DB;2$>
@r8702
CGCACGCCCTGTCCGGCATAGCTGATATTTTNAGGGTCATCAAAAACACCACGTATCACCGCACC
+
@4D!G&*88847';&;DCA%;.$+F?)D"@C93E-/==37:E'4/-DD'%C?53,F=D"CA"((G
@r8703
CAGGATACGGATAACGGCTATTCCGTGTTTGAGCAGTCACTGCTGCGGTATATCGCTGCCGGG
+
1-HF%:!D$B('=5>9/!"+;;;;$1/1&3@12G'G<F@-1(6,;1F-?B*"GH$0:&H.:3"
@r8704
ATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGNTCAGCCACGGACTTTGCCCGCCTGCAAGC
+
(+)3D46E;20+?/,+C*%*&5?(+2(5;="-&E'6;%A4"&GF1->HA1E,8%A.@>AA$@A!#7,,"(3<?*+-(0
@r8705
GAACTTCCTGCCGGACAACACGACGGTGCTGGGGAACACTCAGGCACGCGGTCTGC
+
)BH@GB;ED;BG=*HG;/7>!$#+!2&7,,(F!,G(?)'7E592-G"E<B*?334:
@r8706
TAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCNTCGATAACCAGAAGACCTGCCCGTGCCATTTTANCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTT
+
?C..8:D=;&:C!<$<;..*+)0"18+EC6*1%:H9CC4))%?!(:A.,.EC%)@51.5H)(6"&FF$8A%9ACGH9D5333C*;=AF"8!,9.-#$34:;")8H'1*B6C'
@r8707
GAANAAANTTNGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAG
+
%''!)*($%$"&+&($((#!)$'!%%)'#!!!'!)!)#"*((+*%(#"!%"+*$%!%!*
@r8708
TATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCANATATTCCTGATGTATCGATATCGGTAATTCTTATT
+
*@<,B8=3>!.:HE3;@&5:6#9=$67$G(8.B34+?'.'-%:=$%!7&-:;+:=!/D1D#",;!/FE*/742%H*,+=*?450:.8.
@r8709
TCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTGAAAATAGTCCACCGTAAACGTACCATGTCCACCTTCCGCACGGGCCGGAGTGACTGTCACCGCAAGTGCGGCCAAG
+
;?:F:*5/.B<''H#!2=49,"-)AH="='H1%53!.(%2H1=<?:(,!$2>6%2-E@7G0H%3'"!;:F2&.F(/#?A7<@;:%:,7+*%2@:*1;:A.<5>4+;?//5'3/8A3*
@r8710
NCTCGGTGGTGAAAGGGCNGAGCACCACGCTGACCGTGGCCTT
+
#"EG-<>&.79,"'69&$GG.!3-*0!+GD%H=4<C1*%17B'
@r8711
AAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAACATCTAATTTAATATATTGATATTTATATCATTTTACGTTTCTCGTTCAGCTTTTTTATACTAATTTGGCATTAGAAAAAAGCATT
+
1H43A*(#9B2@<1H/!F<F/2G"E?B11F%;5'G?&-A&//;;-#@?6==A%+=<>D44<-$C6*@07<4)CB%/6CDA;4(8$9*)D-,:!F+#@#B?;C,:.*HH0"?9808B*=':?.?/!H$DA=;4?3)E4@6.<;#8%G80&:G=6&>+)?!#E*H!"C+'"%=E-(<&/!FG:#A@7!?0(B?735@1%+?*FH$3%7F44?-.D;%3C>FF
@r8712
TCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAG
+
(/-%=6("2*9?,#@,C<F@<B*<:D1C-!0)";6A?1>A+
@r8713
GCTGAACACACCGTTGATGATCTGCGCTACCTGCTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTATTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCTAGNTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTGCTTG
+
19)5BF4.ACE;B#B?.5,,/8-FFG595":*1@6D>&1)<&+>4<BB'0CC,#:9&$%!<(%*6B"C-28#@$(2?@=?.44-56?5AHB=5!'0)F+H:C&!&6"E!FH:+?"47#4'9;7B.<*@%CB'G+*.:?2)A#@6:9F*F?EG3?6:0$":/7$@.>&H;*-+%>'H$<&D>@*7-3C@E/<G+0)3.<3A-D&@+,A+>)@'*
@r8714
TGCTGGGTTTCTGTTTTAACAACATTTTCTGCGCCGCCACAAATTT
+
-)C$8F)08$8,G)2<1?7%:D(0<8&4E.7(&C%%8)E*@<25&%
@r8715
TAATGANTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATAAGCAATGCTNTTTTATAATGCCAACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATATTTTNAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCNAGAGAAGCACAAAGCCTCGCNATCCAGTGCAAAGCTTTGTGTGCCACCCACT
+
D53@A?5H*67+,,B!':4!!-='BC<'=<$F.DF?A1GA!F*#>!>>>'!(-%D7;E170A6:$:%/)G=4@:E%&7!)<E!<@G11B>6('':2@-+23@@:4-78)F'>8(GA+1/:*GA-*6&<AA>"$.33#%7F:@:>,0,7C9,9?,$386%"3C/38<1-9($>6*!%1$;0#;##?>014GC*D(G:=*59%"C5*'=17#@:G$&)$-+2/A!,6E**F=7H#24E4?H%69>"-,B@9A-!7H$82<DC!/%=B8H;A?;>0#B2:!>0/+B>73(-%G/.!=A7B2!#4:+E66,A+?#7!.@B<0D$D#1A*%G>6!.'8;;(5B$4/3;%,6B@:94
@r8716
ATAAGAAAGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATTTGTCAC
+
+*!(+#("#(('(#+%*"!%***+!&"#)"+&"("!#!'+((+'#)**'"'(%*+!"#(&
@r8717
CGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACNCTTTCCATGCCGCTTCAACCTCGC
+
C9C.C6'/8,908.E;E:@)(;4?==H%?D29,G$?8(#'#50*H/=C!F:.(92&,''9%!@03B%*9$E=F%
@r8718
AGCCTGTTTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCATTTCGCA
+
"*+()*&%%""%''%+$&))#%$#(%+'!)#+"'+(+&)!&*)%''%"(&#)'!'"
@r8719
TGTGACCGCATTCANAATGTTGTCTGCGATTGACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACANTGCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCNTTGAATAGCCGACNCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCNCAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACNATGGCAATCTCTGCATCTTGCCCCCGGCGTCGCGGCACTACGGCAATAATCCGCATA
+
%+7:?=5-56/!1A3.%8:.6=C2248"EG"E.97$%G77D3=5$218.*3(@28-.*$35;$!?H':%3A1+:$.2$/<'(F<=@8!:55"D@F21C:+$0GB;G:>F+,13D=!#B?>B=F@#&$'';2271,9A<25,!D*F,>!C.0G,?,D347.0H>2,D.:"58755+GA5?2*.:$%3=.%=&=:;C@#A<;2D/0D6:.(8#/<1C9*4;=@!@?==/157544+(;?EF;36A9G*-F*2B4.,47B-'%,1##C6;#,<7*4<&G&E;6225;$<)-<?*=(AB)042'A2"@E"8B9;%!
@r8720
NTTNGNACTGCTGGATGAACGGGAAAGAAACCAGCAATACATCAAACGCCGCGACCAGGAGAACGAGGATATTGC
+
$#$"*"+&$"##"&('$&!)*"$#$+'+)""$)+#)#%$+%#'+('*!*")!""$$'+&$")+"+&#"+#'+*&*
@r8721
ATAAAAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGCCGGGAGTGAAAATTCCCCTAATTCGATGAAGATTCTTGCTCAATTGTTATCNGCTATNCGCCGACCAGAACACCTTGC
+
6D):;G<=DH./(:$;1)1<9B!7>7/5:H6E#/78.!*79+4H*E##<1<03)#?H+8,46>=.,@G/D8%0!1E;(')@8*%9,;$%**"%)2*B$>3%(4=36F5!F7'<!;BA6?8E/!90)A
@r8722
TCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCANGAACACGTCGTTCATGAATATCTGGT
+
,G(!*9=*#10"0+E=1'>3+0"<"/B0'/7=>(D2A:.'!('3#/9B&*9.?-D1C98/5+-@;FD!!12&HB,.69+&@2+)&=0;%:;.?4@-+9
@r8723
CNNNNNATCTCNNACGACANTTCNGNAANNNGNAANCNCNGCATNTNNNNAGGTAGNCANNNCTANATNNNNTAANNNATTCCNTNGNNCTNCNNCGGANGNCCNGATANNAGCGAACNNT
+
!"###!#"!"$!!!!$!!#"$!"!#!!#"!#$!"#""!$"!$!$!!$#!!$"!!#$"$"$#!"!$$""!"!"!!$!"$"#"$$###!#!#"!!!##!#$"$"!!#!#$$"#$$$"$"$!"$
@r8724
CCCGGCAAGCATGGCACGCCAGTCGGGTCGCCCCATCTCACGCGCCACTTTCAGGGCAAAACTCAGCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCC
+
E(*7/$:+*6CE,H8,*D*;C"<'B/8H$4F"1":G;G1&>'8BA,<B,6894#F'$B)(:!=D$::@*G1@3/6!A$C6)0HEG<12;?."7)<7=&!0*?C%:A'F&8
@r8725
GAGAACCTTCCTGTTCAATACCATCATCAAAAGCAGCAAGTTCATCATAACCCGCCACATCCACCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGTCCATTAGTGAAACGNTTCATGGTGAGCGTGTTATCCCGGTGCTTTTTGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACGA
+
1@+2<C;E#;4E.DD7E93'(<C?!&",<-C<F).>1<6<09)";/A6;%3$DB,('53AD0;+H&66#36>:B1C(9)%H#8B)6@68=)@(2'3F,(40>'<+7&C"G),:D-,&+&&32H(.=6:2./>F"-D)GC(,;8:*'4!@CDH,#!13,A(0&27.@="881=G)?G"@0-.1<84*0'>1=$B,8(3G6<227)+9CC5
@r8726
TGAAAGCGAGGCTTTTTGGCCTCNGTCGTTTCCTTTCTCTGTTTTTGTCCGTGGAATGAACAATGGAAGTCAACAAAAAGCAGCTGGCTGACATTTTCGGTGCGAGTATCCGT
+
%9?D23A2G<!E)43<%67-+(F&#H#"*H,#<&B?-'2@2<$?'.?G/7HHCB9B.6C).91!(752(?!4*-B"$G(%1=H%@;A(97C@&1':&=246/FG*%.,>@$DH
@r8727
TGTTCTGAGGGGAGTGATAATTCCCCTAATTCGATGAAGATTCTTNCTCAATTGTTATCAGCTATGCGCCGACCAGAACA
+
&08<-CGE48$>9))+4"26?6?*=+&D3D:@B:*%"=(&,=!**<!4%,E+A>E@>.5>>-&)C8-8040.+F?/)!.2
@r8728
AGNATGATNNGCTGACGGACAGTGTGGGGGTGATGGCTTCCCTGGGGTTCGCCGCGTCGCAAAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTNCACTATGAGAGCCTGCGTGGACGTNATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTA
+
$%"!"%'''''+(%#&$"+'*%%$%%'+$+(#(*&&$*%'+""$$%%''(*#&%++#+$'#'&#((!$(""%"&#$*"'"!+&&)!!"&"##!$&(&#!$!$&)$))##(*%#%$&$((#%!#((+'(%'%*#+&"+'&+""'('&)%"%"&!""('")++"
@r8729
CGGTGCGGCGAAAACGNCAGAAACGAATGCTGCAGCGTCACAACAA
+
45">55BB"2-2'"B)H6!10"$$BF/@-HF#@#$H10-5&@F8',
@r8730
GTNTTGCTTTGCTCGACATCCATCTACGATATCAGACCACTTCA
+
E@-$&.:3EFC6$?(GH3%%A/),E85A)2%@H34.7&4;>4B#
@r8731
AGTATCNACGCNNNNNNNNGTNTTNGNNNNNNNNANGNGNCNGNTGTNTNNTNCCANANNGTCNGNGANCNATTNCTNNNNNCNGNACCTCNNATGTATNANCNGCNNNNNCCNNGNNTTNNGTCANNNNCTNNGNNANNNNATTCNTNGAAGTNNTNTNNCNNNNCANCNNGGNTGNNNTNGGCAGGNNATNNNTNATTGTCTANATN
+
#!$#"$$$$$$!$"##"$$#$$!$$""$$#!!!#""##!"#$$"!$$""#!!$#"#"!$###$"#!!"""!#$!!#!!"$#!#"$#$#!"$!!"$#"#$!#"##"#!!""$"$#$"!"!$#""#!$!!!$!$!$##"!!"!!$$$#"!"$#"#$#$$!!!!$"!#$""!!"#$!$$$"""##!#""!$""$"$!"#!#"$#$!""!$""
@r8732
CCTAAACAATGAGTTGAAATTTCATATTGTTAATATTTATTAATGTATGTCAGGTGCGATGAATCGTCATTGTANTCCCGGNTTAACTATGTCCACAGCCCTGACGGGGAACTTCTCTGCGGGAGTGTCCGGGAATAATTAAAACGATGCA
+
<;/9D'%65..2'&0"/G/0*>.D4E0E<D=1+'B.H:5/55*25-?:*,;B="C5)-5-!4H6'+48(=-H7149+:8B9%B$A%/#&B:!%%A'-.0FBH(:+CD4(3@<6@F*&<)<1%<$D>-#3<3D,$64%-"*-E0HH=,H4<D
@r8733
AGGCGTCGGCTATTCAAGGATGCNAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTNCCCAACCCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGGTGGTGCAATGCCACANAGAAGAGTCAATCGCAGACAACATTTTG
+
/B6=.0C3&;#3H",$=;G=);@0?G<&1)G<'C-F'&>7E>442=!:F!+D""&-@E0)9;9:@)G)<9>1<=4@=@&0''+@="1!2&$$2C5#F6H&+0*-E*-D1G14>C9*26C@@1@4B-'F=H3=CB>%*(4>@3!%FCF&;=%C&%54/<)C<6@#E6
@r8734
GNTAATGCGCGGGTTGTCCTTTCGCGCCGCAGGNGTCGTAAAAAGGGGCAGCGTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCAACTGAAAAATGGCCGGTGGCATGTCATGCAGCGTGTGGCTGGGAAAAACCG
+
81(D;*D&2F!7=F%)411H5C'@8H5-2D-$/(B/F2#=69#2)6*0))1B%<C+&,5+*4*30.@(F%C:@/9%'8*B=B7?6&%2$9DA30EB->!<>=?;@C7B'B!B!7F&&#/<A+:92"#-@3=9;*@%'8(B4H.CBB5>D-'/326?7E8%#'F/.98"=(+,")2D
@r8735
TNTNNGTTCNNCTATCGGATCGCCACACTCACAACAATGAGTGNCAGATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCNGATGC
+
(&*$%("$'*!*))&&+(!+()+#)")($'++$+))"+(!)()&!!*"*('%+#&$+&'!)))"&"$"+($)"(%**$'&**#'!++&(()(!)*'*!()+)%"&)&''#&(%*+("
@r8736
GTGTGGCGCAGATGCTGGNACCGNAAGCCAGAACTCCCCGTATACAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATA
+
6138F9/GH61B1C;;1/@406+3:!@E)E3@=:CG=57FB(:F*.>G6/;B0CAC6,3"DB:5+846$*33#)*(G6H5%+".>)%3!=;C$
@r8737
GGNTNTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTGAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTCTGGTCAGCTTCCCGAAGGCTTCAGCGACCTT
+
*)$%#+#+&)'%$+#+$'%#!$(&$%%*!%'!($')$+*$##'&+%&)#%+*&+&'+%)"%)!!'*)+!*#))$*#!++'("%%!$!&%!'&(#$*$)(%+*)(!!*")&***$#("%'$%(##+#+#!+#(#*(&*&*&*('!&*("')"**)!($&#%!#"'$+&!!&+(&+&)"*$)+*#%!%&'#+
@r8738
CCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCCACGCCAG
+
>3/8'<03#CE,("59#);'9A<"!.-&)5:"892225$3C"":>.21A+@7%*56:0F
@r8739
ACTCGTTGGAATGAATACACAGTNCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAAAGGCCACTNTNAGGCAGCTTTGTTGTTCTGTTTACCAAGTTCTCTGGCAATCATCGCCGGCGTTCGNATTGCCCATTTATCGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGGCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATATATCACCTTAAA
+
-C9@C69D79.+@882.8%?,FF531E<-C(,.G%C(!F.47)7E31!6/-C$=<-#G009,&(#/%E"HC==!4?@$@:,$DE@C&29.GB0&B06;*?@C:F"/%7'H85-"*5%3B1.H<'C>E8A:GF%A,:6'&1??!%$7-6-7;%*G88>%!%0+8G!&9:G'"=D8'<(73D-7":-E9:&B2.2G*'"'B<A>#1=,A#7:6-(;1FA@4B'%'*.@%(-*"8&0'4-@AE(&;CC54?.1>=8'30=3@F!'&C?0?D('.8FGE0-B3>;#7,.7*!B>>(0!=0&5+69GF48FE/@$'08E?FF$>+B7>9'(2BH!.48+2<%+,%61)02,?AA8CGE,A/DA%*(>
@r8740
CGAGTCACAGGAGAATGGAATGGAGAGCCATTCAACAGAGTTATCGAA
+
0B?9-@&2?+&@G=9@>*H,5-E7;@///A7(+'@?H11!+@E11"F=
@r8741
TTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTTCA
+
5&9A)EG0H-5*+!0'AD$)5299&(0E:('2/0/B17-:$/*G6D=5(3-'>7*2.F5&
@r8742
ACTNNAAGANCTGNGAANTAGCAGAAGTGAGNCCGCATGACGTT
+
!%)$!$($*%)*+&*$)'"$('&**)*(("!(+%##)'&+')+"
@r8743
AAACCTTCAACTACACGGCTCACCTGTGGGATATCCGGTGGCTAAGACGNCGTGCGAGGAAAACACGGTGAT
+
45%BG3&)$6G;011F'BEFH3"4,*+$4"1&'/D%F?7<C*D3C25,/@.=BC?>!=/GH)3.$D5>+D3#
@r8744
TTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCAT
+
CB,,95=2%)=6-@(=E0%3E.<D9!)"=6B$/H722(H:.:6@,C'./(64.?,+E;"-F<A50'<+C8/+/0*,'>4"1GG71)79:C@E!E%DH--CE<@@0*5BBB7*/6D!-8$'10F0
@r8745
AAATATCCGGGTTATTCGGGAAGTGAACGGCACCGGGAAGCGGTTCATCCCCTTCCGGCGTAGTGTGAAGCGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGGTTTCGGTAAGGTAAACCCCGTTTTTGTTTCGCTTACGTGGCATGCNGGC
+
&$;?%7E:3(($*6(A1<>'D&!'&?)'E5DA>$E45G429>C/>=:0DAE'=>8/-.74!0,&=@:#5E7(8:G(#A"0=%F5&?1:9)..6.%,#=3;7>@+1+"B?F,5@";H25:@->3$-$9C!:+1A%H4&85<F&H-F+?<?"=GC)"4
@r8746
TTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGGCATACCATTNTATGACGGCGGCAGA
+
;'F/+'1&F:6G;9!H@D,(/G>1#F6<=<1$+$G.5DGA/-F6E76'3E3BAG9AG!+'D#D+27%6AD/=,F>F
@r8747
CTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCC
+
4E#7%&G""*4H)!G>":67<E86C78>1BHF7').1F854H;?H%<F,:7FBD
@r8748
GATGCACTGGAGAAGCATGANACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGCTTTTCCGGCAGTCGCCGTTTATCTCACCGGCGCTGAATACACGNGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGANCTGCATATCGAANTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGG
+
1-=C*E><=;0+,:0(#70&#F*?5;1>H")CC;H'5*B,:-F3=:"0)(,0B(!D%EB1,.<(FG2@E++0D-B>8+&5>*!92>7,B6(60@D5E;#21HE//C>)+E.&'CH&!#'F5&?.F0>D50//DB5D%;+0.<92*1>29.;16-F9+/01DF7<C92.6%:*G<E#HH7H2'%*F$%769!4A:%3/.!=83A8?**3@'0'9@*DH/-0:666D/9EG
@r8749
TTACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCAGCGAAGCGTTT
+
4/E':4!$&('<(,:6F2$<DB6(A-95$6.H<3F:(H.,.4GG)%->:11-=8(2:"CE
@r8750
ANTNACTTGTGCNNNATTGATTTCCACGGCTAAGACTCCGCATCCGGAT
+
&"&!%!('()%)$"$#+#"'"+!+'*#%((%'%"&(!("#(*%*+')%'
@r8751
AAGAGGCAGCAAAATCATCAGAAACGAACGCATCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGC
+
1"!*AF."3=-!21?26!?;&F0F<:#5-H73F0724@@GC.<(.F93B@(4G4-%5'"++</!3</-7=*%8
@r8752
CCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGA
+
+%"$((%!"#$"##$&%"!%!$+&)(!"()&)"$+$$$$%%$(
@r8753
GTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGG
+
)B,-9F9@07/H/6'3@D%2C$AA@?F2?>@E>D.9&)7%H7!=95.G4>!;7;C);*>""<&
@r8754
GAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACAAGCCGTAAACGCCTT
+
(C;CE12(%6A)5&69.$1+=3%4(>6-G?C)1H!$93A=164'3(<8>-D1*./*-(6305"@-&$9:0$63CC&'5*F7A15D&;'3FE3.@(::"
@r8755
GGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCANGCCGCCAGCGGTGCAGCACCTGACCGCAGAAGTCACTGGAGACAGCGGGGAATATCAGGTGCTG
+
9(FB/6F*4!F6';A;F96*??'D8><4:5:-A7?)21@*?<-:.%?*-3,+#,6=",D?#6H+7C92B&$;,;2*6D0'DDB:!?.),#4B'6;F199A.@5CB2C$'.?E*H&6-*1,"/1H2%#DC/2-,<1/;790>'<CH*=?(A$-?&'3GE$F$A(1F5%?%G"G6>"G2EBC<A$F):8*,9<,.D"*!*=-E0;(3/B)B?@<6;B.??C?2);A,<)$A76+=<./9-F
@r8756
TCGTACCATGTCCGGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTC
+
$41%9?9%0!%',);@#:>:&2BG#-HB5!/H1-#/@H<BA>+<<)-/)/F+6"*-0H%#ED%
@r8757
GAAGCCATCACCCNCACACTGTCCGTCAGCTCATNACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATC
+
?*G&*B6GFA26F2?5/B%B4&'72/038;*BC="0"44*G0HH%:-64=,?H;E01(:?D>4/+%@,DC64754E'/8:
@r8758
ATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATG
+
E<95C:!<.</D<D;<<9E=;=#$$&D18A?!&*=@<!,+6%
@r8759
AGTTCCCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCC
+
<'5=4&0A*04).55+G("8B+>3F;8+(<F":D,8"+F"!9%B<')*.,!'08G;)=<+@267<
@r8760
AAATCTTTCCACGCTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTGTGTGCATNGTTTTAATTATTCCCGGACACTCCCGCAGTGAAGTTCCCCGTCAGGGCTGTGGACATAGTTA
+
6!197#G%D.1-5)E?7;7"%-)!<<69("F;A)4((<-<F0178?=/":7<4AC'C$*)G3D$60A43A7;?7"%:BCG*/99=A$&8?!!5<,'1!HC;<A<!)7H.D$@?G40,2,+<.3A"H""*&=)+7;)H'$!4/2-@>HCA.!;+BCA11$>)$
@r8761
TGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAA
+
1367=)*)+#&B?#=6=1+-=4DE6061(8&'2(59*D&'+?+7D
@r8762
TCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAAC
+
.#12D%'/1D;1*#7-!(08'=>>!>'75.,;!.*,@A$&/;@'86H@9/GH->E0/HA5;=)%1/18H0%@3(%<E<"%5>EC'1."(,!9!/=,E?(0!@.('B:7&:6+-.$D55(;$0E16#?'*>=29C.=.(4+>:=21/&&19'/+<!FH=<'9C3*"2CEB>B56A5?'1&4+G58CDE&E!(*-8A6B*<A6#72&63(G'#9:
@r8763
TNNAGGATNGCNTNTNTCGTGCTGAAGTGGCGGCCTCTGA
+
)!!%&$'&#)!!"&%(&*+++"()+##(("")!+&*!%!!
@r8764
ATGCNGNNNTNNNTGCAAAAAAGTGGGGAAGTGAGTAATGAAATTATTTCNAACATTTATNTGCATCATACCTCCCGAGCATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGGTAGTTTTTTCATTGTACTTTACCTTCATCTCTGTTCATTATCATCGCTTTTAAAAC
+
%'%*%(!%!%(%#(%++*"'&(+''+(")#!(%'$!%)%'#)!'*"')!*$#(&&"#&!$'"+)"$)($$#)&)#$$$#)'+#*&'&)!)"'++%*!!!($)%+%"'%(*"(&+*(#"(!%+())(($'!$%"!')#&#'#&)$#+)%%#*%$!#'!"&!$)+*)+*(!!&$+)!(
@r8765
GCGTTGANNNGTAACCGACGACGACCAGCGGCAACATCATCACGCAGAGCATCATTTTCAGCTTTAGCATCAGCTAACTCCTTCGTGTNTTTTGCATCGAG
+
(*$)*(*(%"&#"+&()*(("*+)*%+###!+'*&*#)!)!+++)*&'!&&'!$!"$%&(!#'*#+*"#'()*$#&%!($*&"&"'*!("$*&"*'"$%+"
@r8766
AGCTCTGAATCAACGGACTGCGATAATAAGTGGTGGTNTCCAGTATTTGTCACTTCAAGTAAAAACACCTCACGAGTTA
+
6"'""44:C?>?"'))3F#)H=B7=A&F'(#8H<*(9!B&)'-810;6)G$;='$"!@<9/2>!18GFB!HG6:"4*C5
@r8767
NCNTATGCACATTTAAGTCGCTTGAAATTGCTATAAGCAGAGCA
+
')++##'$'*"'*)*#'("($"&%!*%"''++*&#&&&#"%(#'
@r8768
GCCATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGC
+
:-F,,E20*"@6(#)G4"??1<H:@9>D(G%<<A10+%%$!;;46D8AH=G2=5"B";5*;()4;.7'>7D$.-9%G-.D.)E)H&72>#=7G>>C)GC+#)'6()H+"*-HG
@r8769
TTCTCCCGTATTGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACGNTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTT
+
(0EH52G#9.$&&+(1--.*6A>D-#B+.,?-B(563&,B4>08E"7737?9%4F);G4)3@;;BDHA;=27'H*-.%0<)1C*>);9*<@#@6+0@4":*+,@<3EC"*(->(A0!0A*"3?GB'!,@'3"4G&8!*5"&<$?5&1$<9#&A@2E<%6=8!=4B5F!F<%<%4<3)"6;G5F=G=3"B.79+7CB08G
@r8770
GNCNTGCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTT
+
'%$!##+%$+&'*&+$+#")&&'(&%$"+!)"+'+'*"#"
@r8771
TTTTTCCATGTCGTCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGC
+
&&-F%?96=2>$"8&(.,!=@*#BA195=;4F$5(23(/C7$C!2:+.($;H8(=<&)3"A>,3
@r8772
AGTTTATNNGTTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAACCAATTTTAACATTTCCGANATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGAAATGCCTTATTTTTTTCTACTGCAGGAATATANCCGCCTCTTTCAATAACACTAAACTCCAACATATAGTAACCCTTAATTTTATTAAATTAACCGCAANTTATTTGGCGGCAACACAGGATCTCTCTTTTAAGTTACTCTCNATTACATACGTTTTCCATCTAAAAATTAGTANTATTGAACTTAACGGTGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTTTGGATANCCCACTGTTATTCATGTTGCATGGTGCACTGTTTA
+
"!"()&)"#((+(+$+'$*%)*($!$)+%$')*$+%+&*'+*+#$'$#*#"&+((+')&)!&&('$#%!)($*#)+%+)'$%%%"%'+!(#(+!(')&#*"$$$(+*+)&!&#"!((''($#+$%'%#''!$*'#)'*'"")+"*'!)'!%(($)&")!#!*!$#*"'&$(%*%#&%##()*(+)%(+)!(*++%!!+*"#'#"!!!($+$)#%*%(+*'+**($*%+$%"+###!"%#(&#&'*&+(*"&&*)*%*$*("+!+'"")&!"+)**'#&(**&&)%##$%&$&)$&**"'%!)##!!#(%)$&#)&+(!#('&)#"()*'%#*(%!"'#((+(%&*(%")!'(++#&+''")#*)#+!+())'&(*+#!$*%#$#"+*!"(*'*)')*)'&*')'*+!(+%)*!(#%##%!'(%!'"()'+%*
@r8773
GCCCGTTATATCTGCGAAAAGACCGGGATCTGGACCCGTGATGGNATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGNCTGAATCAGTTGTTGATTGAGTCTCTTTGGTCATTCGCCATCCTGA
+
#-4'>A4)?)2A(7,4&H6@6*CB>@!!6,737)DDE"'1H<D1/&>;&<G#CA+<(?&9'F(54,CD206&"54&;A=F,C6"42?=&D1A,(&@D=F&""5)9A.:715$C)F');%#G',:618%$535H-?387:1!3G-H;0.<"35$;8A.%=;@/8B*0B'),=;19;
@r8774
CCAGCAAAATTCGGTTTTCTGGCTGATGGTGCGATAGTNTTCACCATGTCAAACATCCACTCTGCGGCGGTCAGGT
+
B7#G<:/+A""@CC)88B!/+6):F3<CG1"$='9G06?=,%0/ED<'B22H?@'!#38*.&.,/9,EF8G&7?*7
@r8775
ACCCNTAAATTACGTGACGGATGGAAACGCCTTANCGACATACTTAATCAGCCNGGAGTNCCAAAGAATGGATCAAACACNTATGGCTAT
+
E.1"0<=$&!%?C+DF1!(</DA6,$?@;8:8!%E"#GHC.F&G52=6:@:>=:<D'*A;>",>).%/./DD9)@#/+"?E5!EFCF1B2
@r8776
GGCTNCAGGCCGGTTGAGGCNGCGTTGGTGAAGCACGATAATAATATGAAGGATTATTCCCTGGTG
+
*"#%()((*#"'!&*+*)#%!'*&+"%+#("*&!#(!+#!!+#)"*))&%&)("!+'&&&)&)!*#
@r8777
CATACAGATAACCATCTGCGGTGATNAATTATCTCNGGCGGTNTTGACANAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGCCCTGAAGAAGGGCAGCANTCAAAGCAGAAGGCTTTGGGG
+
*%&(++#%)'!'*!%!)())$%#*('!*&$&++!*"))!&#+"'!*(!'%!$$&+(("+&#'#%%+#)&#")!!*#!''#&&+$"#'#'&'"&#"#&)+*)''+'$%)&#!*$$!*!'((#+)#$!%)#")""&!%)(!"*&+"&'*+)+"+'*%$)##)&(#)*$"*
@r8778
NAANANTTGGGATGACGACTTATTGCCGCTCTGTTCCCAGATATTTCGACGCGACATTCGTGCATCGTCAGAACTGACACAGGACAAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGAAA
+
&&##)"!(+%$*)!)**+&*'&!#*$!$"(('!%!'%+"#%%!()(+("'''""(#(!#+*()!%+*)+#*)&&%&#()"&$##)"$"**+"!*+#$(%*'(*$+"%(!(!#))"%")!&(
@r8779
NTACGAACGCCATCGACTTACGCGTGNGCAGGCCGACGCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACC
+
$)'#'%)&''*+**)+!"+#"!$!!$*)+$("('+&*)+!%&%!)+"%$(*#*+&!"+!*%&+"%')(%%+"%%()%'+*$$+)#
@r8780
CNTTTTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAAC
+
####'*)''$(#+%+!'+)'!)"+)&%(!)()("$'+*(*"&'
@r8781
TGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCT
+
<7@+:;=D'$!F$>@B>75:+-9E'%9B%33A@229.?#!-*#92%EE&0>6*C>HD$":3@F5@7/)4#2<@.3(FH4D'.58%';B?B;
@r8782
AAAACTCGCCATGTACTTTTCATCACGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATNCGCGTGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTNACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACT
+
+:?"#=27?4*:0B-,6:E*:57#H/&5H"H?=+H->0B5C;DB<!>;'>,'$A&;85*H.()7"-&0&F3@+H'E(>)"<;03+(%$D,',0*!8'%7,?,H8?>G7%A1#'-DA>(E)=0((D*CBF7$.*-54G<85#=B&063A58/%1B@CE(778+59HG->A&G!;).5
@r8783
TNACCGCTGAGTNCTATGACGACAGCTATCTCGATGATGA
+
$$27/F!(3"1@D%/70@0:C-:+>%+H,71+>:;DB'*A
@r8784
CAGCACCGTCTCGGAGCCGGAGGTTTCAAATCCCNCCGGCGGAGTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCGGATATGTTGGTNTTCCCCTCAGTGTCCAGCACCGGCGTACTGTTTCAGCAGCACGCTATTT
+
26*)%G'.%9&!1FA9?B;1!35CC'9<;51E%--<>CB@-C-(-!+<4.*.,6"HD85-#9?)%+9,-;B6)9>E771#%8#(>F*:,::9,&:F0)5)2E.6$E":49&5?#9!7>D)@5@$3E)F&>G$;!,H%6/.,E2+C3
@r8785
ACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACT
+
#BCH2-5FE-H0!5'6'C#;#5*&HA+(--#1"E-7069$$2!<6"E7>=(AAC,(.$:30/<9F7!15)@):54
@r8786
AAATCAAATAATGATTTTATTTTGACAGATAGTGACATGTTCGT
+
6",$7%"=*AH,&&<"*8:)@!5=>%45B&F=D2&2B9F:GD%&
@r8787
AGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACNTTCGCGGCGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCACCGCGATTGGCACATTGGC
+
);7G43#3$;B?;,;=,A7=C)+:41@/CD)$:F.2H2:4E8BDFD<3(H<20%++8-C1-@D>#57#-&09.A#9H'4B,=9:H="-?'&H**81&H'93B?1F7-2$@G$+=C>"#+=4;(H8<.>=@7.*.?/8''@4*<?';0H5;-E)
@r8788
CGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTG
+
*9B$76,F4;C%/'H(!,48F<#?984%.=1)$F"@:G),/$/8,!'7-A;>+0!<3)3*,
@r8789
TGCTGTACTGCGTGAATAGCGTNTTGCTGATGTGCTGGAGATCGAATTTCAAAGG
+
D6*B(-*508(?30*4#:G20=1H247-E8&+450,$D&G%@$F7C7&<$%>;8?
@r8790
CACGAAACGCCGTTCNCGGCAGGACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTNACCAGTGCCACGACCGTGACCAGT
+
)879205?@E6!!FH%':E$-H8(E*4$=#)>6A0'5;.3D<H%12(=A4&56+6FE<F$+9B/1;@,792<%>/C.G.<1)A+=G!1H01."H9A$=F6@
@r8791
ATGCAGGCCTNCNCGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGAAATCCCGGGAGGTAAACGGGC
+
3D4$2@1AFF7A>2:&@!3//D219G81F70(?*B17B%3$CCA.2)3.4GG+D:@C490,(E89F,.GA:66,)H0H,;()-%&>9.6%/<5-HHD5!H!#(.<B%?"C#<(3=,9=A:.<)C)/7'A90G*,ACC26A?:7+E/.C4&$%D%G;;-E1C
@r8792
GGGTCAGGATCACGTTTCCCCGACCCGCTGGCATGTCAACAATAC
+
/:/38/2:A<5(*94%/C9>D3=9H("$(F,.<*E(;G=7>93,,
@r8793
CGCAGTAAATTGCGGCGTGATTCGNCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTNACANCGGCACC
+
2G,"+?$2:#8!EB/)!*,:"7?="D:,5?3';B$'9;3C'/B/D-)3;*+F%23F@>!/"!A,=7G+"D-AB)B8$&@@E%"(#.
@r8794
GAGCAGAATAACCATGNGGTGATTAACAACGACGGCACGAACGGG
+
,FC%CE34$5H07(5?)EF3=A&5>=2*.:56,*6D,)G=6C*1=
@r8795
CANNTGCCTTGTTCCTTTGCCGCGAGAATGGCGGCCAACAGGT
+
)!!#(#"(+)+"'%%*(+"&'"%!+&+%))+()'"+(''*#(#
@r8796
AGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTG
+
35!F;#9!?#=82+('#HF384"+)1A)#&/(-%H)(CA&F5A>-0G=+96>)%B:F<**;5*%F?A,3/4)G>96
@r8797
GTGGTGCTCTGGGAAATCGACCTGACAGAGGTCGGTGGAGAACGTT
+
=(:-D#5*),*$/G+%&<%:=$H?>)>B>8>$*57C:.)H<8=/87
@r8798
ACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGNCTGTCATAACACTGTGTTACCTGGCTAANCAGAATCTATAACCGACCCCAACGATGAATCCGTCAGTACGCCAGTCGCCACTGCCGGAGCNTTCA
+
F<+5$A/-/0%!)4@:!0B@!34?(GD(F?:#)A>F/*5%H)1?+C<*2E#</-@.)C'FE8.&(.1>5->-#=*'8.&<<A*&@!2$6>D'&EE<F,9:!(>G3&*,*:H),3&F50$E6A502H%?EG"+>8/'H<5>B:B,<<C,.#!3++&AG:>=(?F)0'E<:5$5'!GF:FA!#
@r8799
CANNTANTATTCCCTATTGAGGATATTTACNGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAANGNCAAGGCCAATATCTAAG
+
))"#%$#+''*!)!#)""$!#)!)**!!'*$*!$"#"$$+($!&(*$!(!&#%'*'$#!+&($"#+"$*%$'%(''#)((#&"'+)!(+!)#*)$(
@r8800
ANTTTTATNNCCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATG
+
&!)'#%#$%"++&'''!#'%$!#""!&)*'$'$(&'*+)!(($*$*%('$)#")!$'$!&*""&%$%&!&"')#(*"((
@r8801
TTCCCAGATATTTCGCCGCGACATTCGTGCATCGTCAGAACTGACACAGGCCGAAGCAGTAAAAGCTCTTGGATTCCTGAAACAGCAAGCCGCAGAGCAGAAGGTGGCAGCATGACACCGGACATTATCCTGCAGCGTACCGGGATCGATGTGAGAGCTNTCGAACAGGGGGATGATGCGTGGCACAANTTACGGCTCGGCGTCATCACCGCTTCAGAAGTTC
+
97="G>@:944?F#%DBE'#G44/?,G2.=9A+<#+1/AC:7F*>C.2!8)G!",4'0-F*&.-C>=3=6!2+#(@1!+@H?1,4F"C/9&2@>BD&"=D1<"G$"D;0+4H4H;#0<B)G4E.4(>$H?$&"C>&--"5<4)(<16'F7;7A<#5->B6956.$C-&<>@9"'("E?5?'/*2E?+4F5$!;'(6))#+:+::&;GH0;1#<;=8E"15//:
@r8802
GNACCGGNATAACACGCTCACCATGAAGCGTATCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAA
+
+&)&#+)&(&&+)!#(+!)#"$(*($(""')"'%"*#&&&$&%)+&!)")"$""#'!"$*")()*+*!''+!%%+$)&"##)$)%#)+"%)*
@r8803
NTGAATTCAGGACAGACAGTGGCTACGGCTCAGTTTGGGTTGTGCTGTTGCTGGGCGGCGATGACGCCTGTACGCATTTGGTGATCCGGTTCTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACTGGCTAA
+
&)(%#)'+"'&%#'&)"+)%+"!'*$%(!&!'"()*+)+)(!%#&%&+#(#$+#%)'#&++%)!+$%&*&*&$(($&)+#+!%'')!+%!)*+)+!(%!!&&$!*(#'#%)!(&$$'#'%!%+$#(&"%&#%!)(%"##"+
@r8804
CGGATCGCCGGTGGTCACNCAGTTTTTCGGGTAACGGGCAGAGGCGTTAATG
+
A3!./$4H/<7*.3<1:)/5<8"$6.04@0")68>##E,)6A*0BD-0-)>3
@r8805
ACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTT
+
E:-D?'):3(#,B>%@7AH1?%*"$1''>,)1",=@=>(-=E;2-&D20
@r8806
CCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTCGCATGACTCGGNACAAGAGCCGGTATCGAATTTTTTAGATCGTACCATGTCCTGATACAGGGCTTGATAATCATTTTCTGAATACATTTTCGCGATACCGTCCTGCGACATTCTTCCTCGGTACATAATCTCCTTTGGCGTTTCCCGATGTCCGTCACGCACATGGGATCCCGTGATGNCCTCATTAAACACACGCTGCAATCCCTCCTCATCTTT
+
-#9$EF+$>>-36.#<;E0,)4*3<!3>2F#><.G62C%;#-(:B*H>*7!,&=9.)"5928E3/0.E@H5;F<01B$597;!<&8?*1C?#C'81$<9BD(5",<D4D40-E(G,!"A6*;,%$C;"6@C66?G;@E*1.>?5+#:$C@5"BH6)B/,475B?9!??;<G$H"G&-E$$B0/22AD3'"%511E@,*B>A<7'E::#CB6@0C5)9;/+/C)4,"'/;F0(,(C>3=4/?9A.EE)*'+8-,C1=E&D7:,41BEC(E,9"'A*>(5#H22B",&
@r8807
TTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGC
+
5++7":@%<5"1/=C('2H;"&B(B%<<G:#>4&@#-+->H@>E$E8:1C<D,</9
@r8808
GGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTNCGTCTTCTGCGGATGGTTATTCCACAGGGACATCGCCACCAGAAACGCGCCGGTTCTGATGGCGTCTTCCACAGTAAACTTCCGGTTGCTGTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAG
+
3F*/9DD(:F:@(=AE',0%1*G<%)DEC+1<'2,.(9?.-(0$D/F><2HHG)5(2>H$7H,>)H>%/C<9=1C0+B/'8?<<8E48($:9%;&602G;;.,*EE+94:9$=?)H::>"</)!:6D"70!@8-?<;:)-FB+2>D!(=+3;5&?).?FF-@2+,.60,,!&'%;D;F7CC;%@>GA)0/5A0D&AFD8,>7'@B+;"2#H.4).,75A0!#?!7>
@r8809
GGCCTGCATAATGTCGTGANTGAGCGGGATGAAAAGTACATGGCGAGTTTTGACGAGATCGTGCCGGAGTTCATCGAAAAAATGGACGAGGCACTGGCTGAAATTGGTTTTGTATTTGGGGNGCAATG
+
C!*'H;B*#A@!;%$:.:5-@A',D<1>8?(6EHA75"-26=:5%26$:GD4F#G3-5#-E!=@1F&/,+F,.*"18F.>CDA,*:!F%<$0E?)=;);433!*@<B!*D-:AC'299B$>'A(59#1
@r8810
TTTTTTACCAATGTTTAACATACTTTCNTTTGTAATAAACTCAATGTCCTTTTCTTCAATGTAAGATGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAA
+
2+':*#D:3868C8@:--@)!1:8!?+D#'!7E7,:0#;!&24;<5%AFG7>/:A2*'5838B+BF;%97:E10:+3(.B5###%&/2E7A,-%5"8>95CC7C2H9$,$(>G)'695CB."5093*<?D:4=+/6<:1@<B-HD??E
@r8811
ATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGC
+
'<'4'H3D),25/?!H37-<63;&;$.7)F>?:F&<+5<9==';@>+9G@'"H(F&#%/>(,E!
@r8812
TCNNGNAGGTAAACTCATCACCCCCANGTCTGGCTATGCAGAAATCACCTGGCTCAACAG
+
*$!&)!+%$*&%"&+$$$)#('+!!*#&*((#$$&&"%&(")%($+*"*)&(%!+&+(("
@r8813
AGCAACCAACAAGAAAACACTNGAAGATTACGCCCGTGCCTTATCCGGAGAGGATGAATGACGCGACAGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAANAGTACAGANAGACGGACGAANG
+
+C7H6D#;?&'55#<=B)//@6+(/2EAF?.EE2)4@59A2,A/0:00":=0E@<#:G@15H-F%@D>-'=G>4E,>//<><5+%:GH%%>/5E-0?5@F3>+1)2'7%0%7'=F&@D-%C/<<./?BG>7.=2>3@F&-G0!5A$3F#!568
@r8814
TGGCTGCTATGGGGATGGCGCAATCACAAGCCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAACTCAGCCAGAACGACAAACAAAAGGCTA
+
4#*+F:G;E0@;%DC4%CE69G/0,&A0?$)*,0"*C0",)=#&>?B9:&E!"8/D%-7'687"-(G'B<>!-=D167(?38,",3E'>+<7G*6,
@r8815
GTCGTATGCAGGAACGTGCTGCGNCTGGCTGGTGAACTTCCGATAGTGCGGGTGTTG
+
/7,:;0$&@)4&!6:.=G)%$.!6H'5:C3"/#(05,8!(:)$>3H61;#@*-5,G-
@r8816
NTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATNGCTGAAACGGTCGATTGCCTGACGG
+
'+!**%++$"'$)#&(")&)**")'$!(*(##')*$'&$($&"+(%#)#$($&+$&&!%+)$&+"**#+!!(!%&$$'!"$'$$'%+#("!*&!&$$($))&!*##%$+##*$&$"'"+#+'+")!!!!$&!&#)*!)!+)+#!'*%)+
@r8817
TATCAGAAAAAGGNCATCTCTCAGCGCCTCTGATCAAGGTCACCAATGCTG
+
$D324,85@".:$@>-&)=6&.F*B@A4/B9!3!6FB/#)*7"."E4!6@$
@r8818
TATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGT
+
/!;!=1&5,7FG?E!7('.(A$'.1!$%D%F'-2G2='AF>C'7F#,?<,8?;>0"2:+G#G)';0.+(?'355,*F#*!4>,;,)C?:&0:(&55633%!F:!13H3#->"!D&+'$#*2/C,$080FG/E+8,2
@r8819
TGCGCCGACCAGAACACCTTGCCGATCAGCCAAACGTCTCTTCAGGCCACTGACTAGCGATAACTTTCCCCACAACGGAACAACTCTCATTGCATTGGATCATTGGGTACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGGCAGAA
+
75'/A=B7#1@(5=#1.+48>:<17/:'3B7/+G>882%$G(+7%".B>#*A'H5A1>.E)9<#C@+A"#E/E3!7-5F>)D&H4.80$A@E@!(;A-<()3..20@$78(G-(@3,8!!87$%;=(;58;/B*(*#!6A@%B9>5.:F<(4-B2.<$+C15&*-=B41;07&A=D+8%CF935<A*98?C.>3%6<+$:4)<"?:833+5&0@G(?H.GG1.H.$G65?@EF/?3A8A.B5A?9@.23#/950;(*1?C<H(F&?@>)>'.>;'="7B<>-,>50$C*,"1*/6+<&/:C/.!B1/A-?05&>)8
@r8820
GTTACAGCAGTTATACATTCTGCCATAGATTATAGCTNAGGCATGTAATAATTCGTAATCTTTTAGCGTATTCGCGACCCAT
+
7)E/A9'=62.AE*'7@%CB$(?=D7&B@&&-DD52C6)A1FC5E2/<F!)BEC+$H#(;#6/<:>!=:(578#A5)3@'8;
@r8821
GTGATTTCCACACCCTGTTTCTCCAGCGCAGCACCGTAATTACTGTGAGCCATCATGACGCCGATGGAGCCTGTCCGGGCGGTCTGCGTGACCAGACGCC
+
2HH!89>"?H%@D&E2>$,>2+"1'A3/"'*-B&B#36E!D.4AC?5%H=$?H#+7A@"$06.C<,7-%>B4"(07>+)/;B"$H/E1:H<A);H8<::!
@r8822
AAGGAANGNAGTCCGCTGCNTCCTCTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAATGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCACTGTTGCAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTAATTTAATATATNGAT
+
*')&($!)&)%&'!***&&!'($*$+*'#+'"+$&$$!++'$(%#+*%!($*&#$#'+"))$)&*)!%&*(#*(*&#+(%$*%"#%")%'+$*%!!%%+++&!$$")%%!&&'&'#$+#'&("$*"#&())#'+!*!#''%#+*%+#(&$%%"!+(%*%%(+'!+!"$%)+$#&$&$''#%)&')&#&)*)))$&"$"%#'##%"+)*%"(#%"$*&#'#$*'(+$*")!&+(#"!'+&$#++%%(&!"'+!"++(%"&(+$+&)#"$+!%#(!)&#*%!*&$(+%"'!&"&!+*'
@r8823
ACCGGTTTTATGTCACGCACACGGGCGATGATGTCAGCGCAGTCAAATGCCCCCGCCACCATCCCGCCGGGCGTGTCCATATCGAGCAGAATGCCGTCCACCATCGGA
+
3FEA!#91+:7!B<*3"DD:A?@)-1#A*=H+*GD((2GC'&4),71%<$B4-@8@:C#9*=%1(-.A+91,@!#D@FC#$9)>8G1(H(:85@)3%%,76"1=/!0/
@r8824
GNCGGAGTTCGTGCTTACCGCAGAATGCAGCCATACCGAATCCGGCTTGTGATTGCGCCATCCCCATAGCAGCCATC
+
#"$#++&!*&&(!""&)$#(#)(&$#*&%%#)")"&)$!$*((%)$$+"%&*%%&"!'!!+%%(+#%++#(%%#"!!
@r8825
ANCCTGCTNGGACNNGNCGGTATATGCCGACACCTTCTGCGCAAACATCT
+
%#"(("%#!)*$"!'%*)(*(%+'*+(''%*!&%'(""$**"#!"*%!"+
@r8826
AACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGC
+
/7-!35-?DA$F9+/8&E(@;*??!:&+;*69F%>>6?/*E@G%6;0F75+61624#@C4>+/FD,+CG1B$(6C7%4D9!/5)!D3.>@"*)2;*:B6<??8C:BBBB-C+!H7!D)F
@r8827
NGCNCTGGCGTATGGCTGATATCAGGGCAACTCAACCCTGTCC
+
!'*!())&!#&#%#'+&!)&!'$&('!&!##!""$&$&&%'"#
@r8828
AGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGA
+
4'?%.<#H2E<01,3<A;>>@&/C2F;0FE04$474(!<A64(D'$50.B28*B?B3B'G)*'/&&4//,;)
@r8829
AGTTGGAGAAGTCATTCAAATCTATAATAGGTTTCAGATTTGCTTCAATAAATTCTGACTGTAGCTGCTGACANGTTGCGGTTGAACT
+
$$)D+6A-CFH9C7,5;%.&%#D#A&>4C*)1>1%=H)$2'$@9&=*)H&HH(G79#%.?3-::6#41<G;5:;0,5!#57;(@#D*D
@r8830
GCCGAGCTCAGCACGTTACCGGACCAGAAGTTGTCCTGGCATGCCCAGCGGAACAGCACACACATGTC
+
D!93&H'+3=#FCD@0H2#:-5?'+H:B5./%:6)&%8!F?E2<$#5!=)6.#5:F@:0<D-E%7>?@
@r8831
TCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATC
+
#H69*,"%!ED5-6H3?#!()%(>#A>0'!4/E=&$2#>4+@E,4=.H#-61===<2;#%-!'D2D("!/*#6E()*(#'")G0;4=%0(?
@r8832
GTTNAGNNCCACNANTANANNNANANAATNNNNCNNNATCATANTTNNNTNCNNNGACNNCNANTCATGCNGNNNNANCTTNNAGNNNTNNNNNGNANGCNNGNCNTGNNNGCGNANNGNCNCTNTTNTTTNNNNAGGNNNCNGGTGNNGTTTNTCAGGNATANATNNAGGNCTCCACNAGNNNNANNNAAATAANNNCCNNCGTNNCNNNNCNCTNGTNTANTNAANGNCTAANCGTNAGATCCNNCNANGGTNAAGNNTNATNCNNTGNCN
+
!$!#!$##!$$#$!"#$#$$"!##!!$!!$!"##!!""#!"#"$!!!#$!!$"$!$$#!$$"$#!#"$"$"#$!"$!"!$!""$#"#!"$$"#"!##""$!$$!"!!$#!#"#$$#"!"""!!"$##$!!$#"$#!$#$#$"#$"##$!##"#""$!$$!#!""#$$"$!!###$"#$$"$#"$#$"#"""$$"!!#""!""!#$$#$$!#"$##"$"!!$!##!!#$"!#$$$"!#$$#!"!!$##""!!#!!!"!"$#!!!#$#!#$!#$#
@r8833
ACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTNCTNAGGTGCCGGATCCAGAGCTGGATGCGTGGATGGAGTCCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTGGCCAGCGGCTATGACTACCGGCGCGACGATGATGCGGGCNTGTGGAGTTCAGCCGATCTGACTTATGTCATTACCTATGAAATGTGAGGACGCTATGCCTGTACCAAATCCTACAATGCCGGTGAAAGGTGCCGGGACCACCCTGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGACGNTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTGACGCCCGGCGAACTGA
+
.2DGG*34*9-!A+6?C?)(,2EH2/<&A2.%?/C0/#0B6)+!B6#*H5@-&'$F=3EC*&B:=6EF4'1!84D.+2H?59AD4DF-H2AF<!%?%/C.8#.AB0B0F0'F:0G-%9..7+)*1=/G+'(:G??)@=4/E0.'<&D&#'-A!F0E92B;C,)0(9(D=;&6H)"'B#H/7:$1'>->)023B7.E)1(7<B!F13!'>3<:,ABE#.<?>//+9F>@6#5%>4H)>8+&"?#+7=C3@+,CF3:?,-A3H.$)52$=5>=8@:G,%H!:7*%2+''@'?+H%$/GEGG%1>97@$43=@1B<FAG"0%F&FE!=:"H*3GH"?)&>4EH*)*(38G@AE?(<;(E%<244($#+.8!/A&,D,C@/!7AHC982H*E<./?!8?+(@2E27.;69*?G13.H5C)1&;="3-<,D5
@r8834
TATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGNCAGG
+
+C;)@*?G<6H#E#>3(+$@D#F?4DH1,/0(F="<698=@#D+(/2C@%8E.EG?"3;5D0-
@r8835
ATGGCTCGATTAACGCGCCAAGTTGCTGCGATTNTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATTACTGGATCTATCAACAG
+
++"&#"&")"*"%*!+'*(+#*$*!%+!(#!("&&')(&%#)*$'+%+)&!(*&!"%(#%!*+%++*))"(*'#!(+)"!*(")'$$&"&*+$+#*&"!$!"*!#)(&*!%%#!$)+(+"
@r8836
CCAGCACTGTAAGGTCTATCGGATTTAGTGCGCTTTCTACGTTCGTGATTTCGGTTTGCGATTC
+
9%&G4*<,9H38F<H?-616#!-HH>$?'C#3@)0FD8>73=7?=32=3141")"<>"%G(CG@
@r8837
NCCGGTGTCCGGCACGCTGGTCAGCCGGACGCCGGCGCTGCAGCCGTACTCGGGGATGACCGGNTACAACGGC
+
""=94>*%=*8.+:E5;A/8:(E.EB<@"?&9B@4>5!1/0:CC-958?!+8!9*:H&&2?,%-#7.3DF1@/
@r8838
CTCTTCGGTATATTTCAGCCGTGACGCTTCGNTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGAGTCTGCTTCTCAGCCTTCTTTCGGGC
+
+)#(!!#*&')&!#"$'$%)%%&!)!!&&!&)'%!$%$+"'*!&)"%$+*%''*%&!&"&+(*"*)$!+*"""**(*$!((##'#$"&"+#"*
@r8839
GCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAAC
+
')*+&%!))++$*++()+$**%(&$!&&'*"'%+(!($'(#$''*
@r8840
GNAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCTCTGGGTGAACAACTGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTG
+
)!%8F(4;*&+#:!H!C$#"8:"1E.2@E@,-.CC.D$>."5)?9)<39''4&"82+#4=G()C>9$?;D8&!.4**=*;+%*<)@0%3(D$2)93/"D*19<;!D**#5&;CE8A%2)'E>E*"1$@>9G7)8+
@r8841
NTGNNNNGATTGTGGCGATCCGATAGACGAACGAANACGCCTGG
+
%)%$"##%("%)+'+&$+"'!%$$(!*)'&'+'))!%&&'&+"'
@r8842
CGCGCCGACTGGCCAAGATTAGAGAGTATGGGTATATGACATCGGTAGTTATTGTCTATGCCCTTAGTTTTGTTGAGCTTGGAGCTTTGT
+
BC"<)"<4A"ED2H>0)@4%!!((B47E$35&./8AG#/%4:F3?5EG)#F<2H'0G3@':%#>4.7*B,?E7)3'7/2#328:26A:;1
@r8843
CAACTNACTCAGCACGCGACGCCAGCACGTCCGCCGNACAGGCT
+
6(),;?=3;>'8@2:%9A+G8./*C-'/C(9'&G!FG5-524>;
@r8844
TTGCTGGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACAGGTGCTGGGGCAGGCCTTTTTCCATGTCGNCTGCCAGTTCTGCCTCTTTCTCTTCACGGGCGAGCTGCTGGTAGTGACGCGCCNAGCTCTGAGCCTC
+
H%55C,A&(>,,,H)=#?=;H>3*551(/6:F".#!67)"B51E6E(*B<+B6>/E'1GB<E1:=C*@!6H,:.F,65,2#.@/#FHA2@.53/(7-C;69%C6'=4#<&&--?2985C9C6+'GD9")),8$=C-@)A+C-@52"
@r8845
NCTGANAGTCCCNGCTGTCTGCAGTGACTTCNGCGGTNAGGTGCTGCACCGCTGGCGGCGTGACACCATTCACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCG
+
''#&#"*%&'*(!&$(+*+&!*+''%*)')%+*)#!')("((!+(!&$++(#'&!#%&")+!%#!!+(!%*#(!$$#%#+!'!')(%&*'%%$)$!()))$'"#'''$*&'##')(('"&#$+%*!!*&*)"&$#"''$#(%%&%!(!*+)'(&(**$(+#($"&++&*&#+&)")%(#"%$('&(#%('%"'%"$(*(&((++%'"!%+)%(()&#'#
@r8846
CCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCNCAAATTCGCNTACACGCATCCTGCTGGTTGACTGGCCTATTACCACAAAGCCATTCCCGGCAAGGTTAGGAACAACATCCTGCTGCTTTAATGCTGCG
+
>E)7B%=3.03++!@'2$.H0;:?2+3*<#HH#5>7!5/C'262:"!;0>6)H:"EB;.52"(#;<(@+<*"A5?#;:*E-<7?:!.:3AG=&C00)8#<9$:7/66-5BH61;B9?A&##8*A?1*3:/::$D,/DB=GB.%&5,$4?:#
@r8847
AATCAGAATCAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTCATCAAGCTCCTCTTTCAGCTCT
+
!!$#((*(*+*!**&((*!+")*#'#!%$$("""%*%$$))"%"&"'#'%#'*''!%(*''+"$$)$*"((%!&)%+$%))$!('!&)%&$('%+*')&#!%&$#*$(+%*"%)+%+)")(**&%&#&*+
@r8848
AAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGAT
+
C>638HHB=%E5=B*'6''6@D+6@%"@GG0E8H//;H%3-==C;*44C'0-%(*6*?888%>B="H)'4#F:7#E::&"F-)+**35+$,*+(3E?FH5-+"8-A2,9',9)/>:-,0D+F=2$02G26,"7$=-%719%B2<80"@@+C;")4-84(3@%01*:77!GEG#745E2'@"<*0%<E$4:2''3.D1-FD%8(G<+;<.>EE>",//7)1-C
@r8849
TTTGAGACTNCTGATGATATTTCTAAAGTCGGTTTTTTTTCTTCGTTTTCTCTAACTATTTTCCATGAAATACATTTTTGATTATTATTTGAATCAATTCCAATTACCTGAAGTCTTNCATCTATAATTGGCATTGTATGTATTGGTTTATTGGA
+
6+$@(:C70/5'!%&9A"A%*=)5//)/%!/H?=CD-1G.F=G+)4G0(;"9.0)(/>'4.F?@0->.?#&!E4)0G5;!*6E&0>%G3A-=#)*EFCC!B%9D';0'6+"6'?><$D94G;C90<;87F$G&?*&G(+27F'77H%+D&C0;A>
@r8850
TCAANGTATCCGGCTGCGCTGAACTCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCCTGACCGGCAGTTTCATCCGTGTNATCAAGCTCCTCTTTCAGCTCTGCCACACGGAGNGCCAGTTCTTCTTTCGTCCCCGTCAGGCT
+
$@3-.&(-::;E1EE8?//+=B'G1<70GDG-D-77<GF@+*3>)-81F$3;!(4E&A8=)$8B$&+:%;+"EA6D2$2>1!+436#-"8&*@$7@1B(&->70+D66:$+/H4?;5'4=7223997?3A.%GBH/"1*.#3%:&3@%#<)+41)/#G0.27*
@r8851
AGGAGGGGTCTGCCTGATGCTCCACTTGAAGACATCACCACAAAAGAAATTGCG
+
.,A=4:.=356E3&@<9*#?;BGCDG2/)B*9@7'=1)!&'=@G,<$""*;38&
@r8852
AAACCATTCTTCATAATTCAATCCATTTACTATGTTATGTTCTGAGGGGAGTGAAAATTCCCCTAATTCGATNAAGATTCTTGCTCAATTGTTATCAGCT
+
3D@#/4>;6)C)#>+/,9;,60.>@7@25E67AF;>+<@::+>,1.=$085-$DF0<02(#@?&G/A?2AF0/)%6GB*'.C1113'!?70B2*'A%@;$
@r8853
AACAAGGTCACCAATGCTGAGATATCTGAAAANATGGCATATTGNTACGCAAGAATGAAAAGTGATATACTGGAATGTTTTAAAAGGCAGGTGGGCAAAGTTAAGGATTAATTATCAGGAGTAATTATGCGGAACAGAAT
+
D>/)B81-E%?=&@,1F-E!D#%A06!H.+8AGE6%0$C&G8E)-:H*>6>+.B6$G#)4)1/H83>H'68H+BBB(+FF7..#4D1+=5=*B<D:"*/,.)18&$48EG0G)+*)4+=3;3%CH*D1/&0!8/>!<)&"
@r8854
AANTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGTCAGGGCAGCCANAGTCACTCATTGTCCGGTNCAGCCGTGAGTG
+
%&!+#+&"!)""$%!$&+*!#!*)&$$%*#&(("$&!%*&'"$'&')%"!#)+((+%""$"&()*&!*+&+&"()*&#*&%%!%)'"#)"!$*!#$%)%)(&('#$%
@r8855
AGTCNCCGGGGCCAAGTCAGGTGGCGTATTCCAGATTGTCCTGGGGGCTGCCGCCATTGCCGGATCATTNTTTACCGC
+
,+8&#<(C&*F/.1'B>E;7,&40C,@2=$1!D,@!,,DH7#1%+G//H88";&(4?B"C%3<FGA-!".7*@3'$5,
@r8856
ATATCATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATTCCTTCGCTACC
+
5'#?8:16-C6,;?30$BC!?2GDE5>#"F"(D+<A+;CG.B>/E"E4$$26A/'EF0FE&"
@r8857
GNTCCTCTTTCAGCTCTGCCACACGGAGCGCCAGTTCTTCTTTCGTCCCCGTCAGGCTGACATCACGNTTCAGTTGTTCACCCAGCGAGCGGAGACGGGCAATCAGTTCATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGG
+
65%"?>*.4)<H4H":,7&A3CE?C$*.F"F'=)*454/:'8>1:'0-=4$E6?>2;)!>+GFEGC&/;'.,7#68;EB55:8"+G2=>6%"A8*-0+8/FC1G=D*G6<A+%6;=8<>,D?815<H>CG4@3(3+G0D*G888*83A*>8+=F?
@r8858
GTGCCTCCTTTNTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTC
+
?A446,386/:BAD=5)-/7A2E6!>*6;4>?DD8&E,;='9CA(*!(G#@.B*9-4+6</*E1<DE0%<$#*=-05$5#4G3<4
@r8859
GCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTCCCCGGATGTGGCGGACATGACGGAGGATGACGTAATGCTGATGACAGTATCAGAAGGGATCGCAGGAGG
+
B=@!DA7/=8+7!;)">FB?12&(0).!!.=>>095FC*0/>G<#4#95+81-D=?"F8A@23<B@CFCD:?A=8C>6/7@G(#A+75$E>*:"'>5;$9E%$C&@$98CD(5<,=!42
@r8860
NNNNNATGNANNNTNCCTCNNCNNAAGNNANTTTTNNNNANNNCNNNNCTANAAN
+
!#$"!""$!##$$$!$$$!"#$!###!#$!!$"$"!!$""#!"""#$!"!""$"!
@r8861
NCTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACT
+
#!C&!.&'8)%D!F47$+*6/251*.G#6"77::1D'<&;62G:9A82
@r8862
GACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAA
+
*7C+H21"G.2:"%5D9/66EC/':(5>0<48';63%GG+=F$5G<1646H=%+,BF8;4A$26)B+0@H5'"')C,=E8($@B:?G"#-(&4D7AD+611'E4*)B4/+?"'<')E"5&#8$H:);50E><1
@r8863
CCAGCTTTCCTCACCCGGCCCCCATCCCCATACGCGCATTTCGTAGCG
+
483)@,;=$;!B?H6*(>4!*-=/&F-#<$;0.=&#8%G#3-20*,"?
@r8864
CGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGC
+
7H74HE8G)$822**G=,++=('!2>B685!)<C.?A-D8;3>E>CGFH1F,)A3>H&4H4<@2,BE783G+)=H8B">$HA94744%
@r8865
CTCTGCTCCTGCTCACGAGCCCGGAACACCACCGTGACACCTGATA
+
!4$3@&$/-)A=/8(*"65(@&12A4,=;FD-6C/9)A=&+'B&?-
@r8866
TGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCA
+
D#6!;-B0/A4<>03.0%;>9H8)DE4H'45.)C4:@B8G98@&<6!?<&!!(.H<<-&389;FE:-/E
@r8867
GCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCCNANAGTTNTCAGCTATCGTCACATTACTGAGAGTCCCGGAGNTCGCAT
+
?4@9#3;3.!<H.*91(H>=-9.-&/:7+&$,'9FA;$/$G0@7<(:6;:3-DEE<,77,!@F8$+5;D@5/?<C18/?#GGD60#>#;-9&)A7%D5&>.,"4>9
@r8868
TGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCACCGGCGNTTATGTCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCG
+
@>?%<+=<:"@*B0(B4;C>8>*90*GF@>4+4C'$18C?@G,GF,*(-,H-275#=2"9(5)7E;CF1D6"6@+?22A<&+'$E42@09CF4
@r8869
ACTTAGTATAAAAAAGCTGAACGAGAAACGTAAAATGATATAAATATCAATACATTAAAGTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTA
+
;$<CC9A1@;>7$.H<>6GFF#8<@*3GF(431',B(=/)0F5)+91&?*%<GC4@HC19).7@63679?7&,/<'%>B?$3E."D$2.61@9:&"4?/:>!@?8:-D9%GE&E(DG0-A(C81,%"262E>@H8
@r8870
AGTGGAGCATCAGGCAGACCCCTCCTTATTGCTTTAATTTTGCTCTGTAATTTATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGAAAAT
+
9BDBC3"G>0/=@C@5*F0=C.4DC+.7A>F=*7?9;='","+/=7E"(F7?!?17D2?@7F40/!5%>%1&A7(CF;B*-8:>!.))?7@';F-GF'>#=!0@4C."'7;G5$$F>D>'1HD7G*%("!'7$1:@3A<A==#)=;2243A#BD,*!08AC02-?%<8-49E&99";$<BD8
@r8871
GTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTNTGCTGGTCCTGTCCAGAGCCGGGCAGGCGGCAGGGCTGACGNTTAA
+
,,*/1HD',H)->,@(*C=/3E#8B920E#DE%=78%HB,GB3<8/D?,6$@?%=07".*.0*../"<$777(.A741(7%4+C=C
@r8872
GTGGTTTCCANCAGTGCCTGTACACCGANGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCAGCACCGTCTCGGAGCNGGAGGATTCAACTCCCTCCGGCGGA
+
D8#=:#G/<CDH3.:0!#:;F><F<1%E4F+2&+"-6288+.1%#G5@";,(7-"?D)B1F>*.&&6%G#A7644,#!'.1G1&-=1!:.9<+2C4,:)>/90,<#9D?GC/B$@,&>%7)'&0FB#<#(H>$!*>B;78*E.=-'3
@r8873
CATTTATTAAGCATTTCGCTATAAGTTCTCGCTGGAAGAGG
+
=@0EDE(!4H3>8:9>A=&D=&G'53=ED+1F1$G2#1?%%
@r8874
TCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAG
+
HD<19*#D39!$F'51@6$%*,'C;=-F#'F.??18!?4!,;?,="<0>!?-<&3=1'2>$#@,#:/HE#E#.5..@*0+>'9F(='4@H42;5H6EC>$,CA9*/4B>
@r8875
TCCTGAGACAATACAGCACGACCGCTGGCGGGTTTCCCCTTGATTGTCCAGCCTCGCATATCAGGAAGCACACC
+
G#+''#A/8B788HG1H7(A>$G@.FAC,2@=@39"#:$"F=73:('?B>3"!9"?A>7>@9:#8537,.@H%A
@r8876
ACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCAGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCG
+
F3#E5'9:B)52B46?@(!9?<;%#0CB15+@86"@'**()&H%)(F%"G%<$.<*?;@*16"$?H<H/%3,0>=%52:65G$"2F3FE4&%.5G2=7G8A)B0G!A&>?)E%6EB#C3;$;AED@&)AB8(2D"HA:+)D8G1=,<A)F$%
@r8877
NANATTCNTCCGAAGTGGTGGAAACCGCATTCTGTACTTTCGTGCTGTCGCGGATCNCTGGTGAAATTGCCAGTATTCTCGACGGGCTCCCCCTGTCGGTGCAGAGGCGTTTTCCGGAACTGGAAAACCGACATGTTGATTTCCTGAAACGGGATATCATCAAAGCCANGA
+
#)#%"*(!!&!+)'%'*'%"*"+'#!'!)+"!+$'$&+"'!(&$"$&$#'+++#'&'$'"'(+*($")%*$&$(+"$"+*)(&%!*#"")#$*%)'(#+&#*+"+(!*"#!'($(+%%&$#%!&+)&(**'#')#+$*#'&%!(%*#!)*%))!#+'"'#(!&(*++&!()
@r8878
CGTGTAGCATCCGTGCAGATCGCCAACTACCCAAATATTTCGGTATTTGCTGCCATCAATTTTTTCGTAATAGCGCATCTCTTTCACTCCATCCGCGATGAACCATGAGAACGTCGTTGACGATGGCGTGCATTTTC
+
@#HCH/0=,F,-$"2)+3BC?ED(==+&%6(31.GHB,$!31$CCD!8+-G>E$:,577EC&6'/A=(:'7@:!D>!#C<8&F3.=3#)72=#/+$-C)?9*3&=!9)$.@;HG+,H2",18-9),4>>,+EF-H=B
@r8879
ACAAGCGTTATCTTTTACAAAACCGATCTCACTCTCCTTTGATGCGAATGCCAGCNTCAGANATCATATGCAGATACNCACCTGCATCCTGAACCCATTGACCTCCAACCCCGTAATAGCGATGCGTAA
+
+>)-;B1-B61#.E=28+G?A82/24C<:"!,"('&&8*B$8DF-9@B@:4<A2:)&C-.AC=:.G+!HH$"'(*0E:<3$&)D@0,-FG:!HC=7-%$"2.,#&*@6:$?)FCE%*&$$@,58&/6;%
@r8880
CGGATCACCGGAAAGGACCCGTAAAGTGATAATGATTATCATCTACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATTAATTATGACGCAGGTATCGTATTAATTGATCTGCATCAACTTAACGTAAAAACAACTTCAGTCAATACAAATCAGCGACACTGAATACGGGGCAACCTCATGTCAACGNAGAACAGAACCCGCAGAACAACAACCCGCAACNTCCGCTTTCCTAACCAAATGATTGAACAAATT
+
7A&B9*.A!,A4;(%F9D7?E?'55-*#3*&#D6E"5A!A(.#/&H4:'7G+2"%()7$+&"D'8;C27<E=9#DC$&<-D*7C,?F#8G.$/%$2&&4<';C=AA0<'G8+)@GD:5HD##CE#43D;:3B(+2-)16;EB0,B=5:?<'(*<4@8%;B2,!<(?AG9"0;>=$-=-10GG&8?"5?%@4;*589>555H=/242G+6/@B":<2#92F08&<0A>@8-2E;<*A9E-&;%D;>$7C*)@,@"0>5?0"'H>B
@r8881
TGCAAGCGCACAAAAGAAAACCCGCGCATAGGCGGGNTCAAGCATCAGCGGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCTCTGCTGTCACTCTT
+
>"<!2%5+C#24E5;H3D$6HFH@4/:+%4*<1EA")D<=@'@A4=.5**%$#E.;(H:G=!-4FE-<3:6G,9?6.>'F.6*F3<@!(#9+!B%13@!6#,H+,9(4+
@r8882
AATTGCATCTACTCGTCGCGAACCGATTTCATCCGGCACAGTATCAAGGTATTTTATGCGCGCACGAAAAGCATCAGGTCTTTCCTTCGAAGGGGATCCGCCTACCTTTNACGAGTTGCGCAGTTTGTCTGCAAGACTCTATGNGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGGCATAAGTCGGACACCATGG
+
,BB41;>1"6H71?#+().,8F#A4:5&2'616#''+F='H5B-"*2=6,1;"##D?-AE9)1);9E1'"9B0F.9>278.!:049B&+G.F!5!4-4C?CD9%&<=7>*4A%37@)"%-:&G34+H,/2$*(5(82,)1B9>>$'%-A5B;=%+D$63%5#)$C.1"<5AGFCB&===<C3/!C>?C*B2;DF='?HCEC%9
@r8883
CGCTGGCGTTCTCGCCCTNCGTCGCTGGGCGGCGACCTCGCGGGTTNTCACTATTTATGAAAATTTTCCGGTTTAAGGCGTTTCCGTTCTTCTTCGTCATAACTTAATGTTTTTATTTAAAATACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAG
+
2>)(*<.&,<*5H28/*#21!$>6'7?%;$1,?#H='&%4#-,;A-97-%A#"128'=F$G!;@/+"*E#$.C6F,>!8/)+65+:7<%"4%D&A<FG--1#>'/EA6G",GEA>02$)G4'!5.%(='/-1227FD=1F>5-2#E)/)90&9G6C#4CBC6+)
@r8884
GTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCANAACTCCATCTGGATTTGTTCAGTACGCTCGGTTGNCGCCGGGCGTNTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGCCGTCGTCNACGACCCCCCATTCAAGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCNCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTTCCGCTGTCTTCTCAGTTCCAAGCATTGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACNCCATAGGTGTGGTT
+
:H#=94,C&2#.BF(&;#!0D"<;G6'#A:G86@F+94'!%E7DCG+*.7G"$=?F(8#C5"1)0$+0@3?'2,$;*H+A8C&6A!>E,F%5)(++&G1'E510;#@A=F9$7+4=2F<?A:G@DHF?-14EDD9A+GD/88-E,)0/):)G((G=1,5#&*8+"#&8(/92>6HGH><C-0?,27<"6$$=)20(*G,:?+(4F2"7%649)6C*:@D@4?"BFDB(74;&AHAC<8950>6)@.:);,*2+5@*2>11G)+!.,7)''BC::H+5'5??,:(-G7(2C:8):!!D%$*<5?<B:E'5-@$.E7C"@AG-.>-&,3<G"6/2$;376,-D(809%6F;;)D3?BB"7-#$%%=:9EDDC816&E,25F&G*A&;70/(,?160BHCD+(B6F$/@<
@r8885
CAACGTGATAGCAAAACCCCGCTCCGGNAAGAAGTGGCCTGACATGAANATGTC
+
08:1;E%02,@=9GG'77,6)(;AE1C<'1$%D=(>A<1!D<%"!=:(G2<%08
@r8886
GGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGT
+
D3$$*@30!G*C+89/C*2-?AF).E"<:42+F>,+?4$5C#7*,&3AB6(57&C8'
@r8887
GANNNGCGCCGTCAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCTTTAGTCATGGTGGTAGCA
+
&!&##'+$(+!*!!+**'!!%*%)$("&*!(!"&&%'"$#)&!!&&%!!*$)+*&!''$&(!%&%"!
@r8888
TGTTTTCTCTCGGTGCCAGTATGGTGCTCGGTGGGGTGGCGCA
+
E6-';)A<4<-0#;+64B&>=3;"%!6E'&5;%?DF&E$5=,'
@r8889
TTNNCGTCGTACTGTTCCGGCATGTTGCTGGCGATCCGACGCCTCTGCTCACGGTCAAAGTTAACCATCTGTGCGGCGATGTT
+
#"##+*#+""+%++)$*$$&+'&)"""#)**&(!!&"%+$!&%+$**&#+&&%$&!$!""#""+%)#)#*+($+#"%('#"'(
@r8890
GCCTGACCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTNCAGCGGTCAGGAGG
+
5;$F)01#-"3?#)A#>>-.4;%!D":)G225B?'?C6.5HCEH6E1!8E,:%B@D@
@r8891
CGTCCACACTGCTTTCACGCTGGNGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGCGTACCGTTTATCGTACAGTTTTCAGCTATCGTCACATTACNGAGAGTCCCGGAGTTCGCATTCACACTTCCACTGANATCCGCATTTTTAGCGGTCAGCTTTCCGTCCGGTGTCAGGGAAAAGGCCGGAGGATTGCCGCCGCTGGTAATGGTGGGGGCCGTCAGGCGCTTCAGGAACACGTCGTTCATGAATATCTGGTTGCCCTGCGCCACAAACATCGGCGTTTCATTCCCGGTTGCCGGGTCA
+
#6@(>=,"7=,=$,F'<1A@C94A;!&5:24.-B4:.A'3E04#+1!%3F.-E1<E?)!1?8&<B60=499'@&)A"C'1&$>9-%/8"7"B4+:';3H!D)007>E>A:/H</94.;(7A2#35<$&&?1B$+1,CD.8.+@FD"/)"DH7A3)>''(-$/4$H*$F68=2G*-;C*C(#7%(&$"@9G(=4G7>B.,0,(67;5''%H&-8/4%3*+4?*G30H4,6?($G;H2EG*%1.1;&+!$?+;9<2)'0*:=H-D5-:@0AD?F*8,@6BF(H":F=="E<8<)A.E+0/")741;%5+(H@*G5,=:,C0#0'9>6)
@r8892
CTTGNGCTTGAAGCCGCCCGAAAGAACGCTGAGCAGCAGACTCA
+
)#'((%)+#$%#(%"%(&))*)!$*""'($+("#!$'%%#!*%*
@r8893
NCNNTCTNANANNANGGATGNTNNNNANNAGTCNTNTNTGANNTNTTGNCGANTGNGGNTTNNTCNTNNTGNTNNGNTTGNACNTGNNGGNNANGTNTGNTTTTNANGNN
+
##!"!"$#$#!""$"###$#!#"#"!$!$$$$#!##$##$"!$"#"##$##"!#$"$$$$#$#$##$!!!!!!"#$$!"#"#$$$#"!"$!""$#$##$!""$##!#"#$
@r8894
TTTCTGCCANCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCANAGTTGA
+
?D"%&/%"-51,%:@&(!*%7'%4D@1$)6':C<?1(8:3*=-6G8>9;3>.58
@r8895
TTTAGCTACGCTNTCGAGTCTCATGCGCCTTCTCCCTGTACCTGNATCAATGNTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTNCACTGCTGGCGTATGACCAAAG
+
:AB2.-!)#"->7ECH5''>0';#DCC'B45E04'77F*<"'$G2@$>E@5#*'A:+'<60<1BD*0700+16-14+9F+3".#:12>94*&=@A,(B546G$691&=/57;53G'>?78-)C/;2,;)13@G426%>
@r8896
CCAGAAAAGCAAGCATCAACTCCAATAAAGCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATT
+
$):HB"*E3)(GC4$(DH=,1(A7CF/9)=5BC,<.4<8;HH%#A&A7DF=-;'>AC*':)>$26<#6(=5#B-C81CE0:=/A
@r8897
CGGAACGGCAATCAGCATCCTTTACCNTTCATCACTAAAGGCCGC
+
)@(E,%.63B+?A+'CB&74%<)595>G7EA7E:H@H;D3D9;0(
@r8898
GACGTNCGGCGCACAGAAGCTATTATGCGTCCCCAGGTAATGAATGATTGCCTCTTTGCCCGTCATACACTTGCTCCTTTCAGTCCGA
+
"'(+)*+%"")#&*'()&)"&$!"+$!##+"#!*!&$!&!!()'#')!&$(%#('*!")$!"&+#$"*&*!)"$)+*#)$'+'"%++%
@r8899
TACCGCAGNAGTGNCNANTAAAAGNCGGANTAGCCGTTATCCGTATCCTGAGCCGTCTGC
+
$&'($$()!)%'*'%)&''$*%%$""&(*+%)*%!)!!#"(#*("$(&$"$%($*)"'$#
@r8900
GCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTGAAGGGAACGAGTTTTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTNGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCGGGTTGATATCAACCAGCAATACGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATNTTCACAACCTGTATCCATGAAAATGTAATGCACGTCTT
+
34$*-*%'=!'@(-:F.!?*>C9)>F=-E=%>"7853;2C!H2*?(&(7#9H*0(<(!+4+"F35#9:)!F,)C<&:>=3+!=D>(>:<2#5%">?:<1*8>%:3?3#"%C!D@,=G;@:8A2,::%;366$E&=51&1A)!-#.2:>9,B/0?%:8,:2<#-%F#<#7'9+9#;,$)2D:H,=*=B1@!3>1</%"$!D%,*0,26;;DD*@HB@DH=3(FAGD;/C;)-;!C%8-4#:C,9#;?EC--98+"#4>64,8#/07;6-7AH4'E2E92"2$7+=A:4-*!)>.@0-)E0B3&%-A#>27.0"$H5?.AA/H3@0;+*:DH$2+<(B/B?15H6G#7%@9@5&=9"@"!-B25C
@r8901
CAAACCCTTCCNTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATCGCCGGAACGCTGCAACTNAGCAACATACGCAATCTGCTCCGCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCGGAAGGCTTCAGCGACCTTGTCCACCTCCACGCCGGATGCAGAGGAGAAACGCGCCACACTCTGGCT
+
,;&?6G2?.F0=2E42&*=D=*)H63?*#&H:&E!8A<)@&9FF1*8,3-3-9#AF+";+,&E4G8-E*')8>5&&+(7@%!E7'C5%0.B%.G'2(&(-/6%D&G:F3)=5-0<&#&A@C"?-G:?-/*>/%1D!+%F5(DB.9)@-)?@#F&7A1=1D,3!+FBH,FF)!9?E-!7F#6=3C1$088+>!&8H$*4##>H5#GC7H#"1&C+!@*E6?-:&8:$
@r8902
CGGTGGGCTTTTTTGTGGGTTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACA
+
E?$<%A>F+-!#8);F/?5AE32-040#97@%>52;E:*9,:)HB$2*H#58+4$F=;366F4?
@r8903
GGTCTTTTTTGTTGTCGAATCCAATCGTATCCAGTTTGTTCATCA
+
CH--6<:7>()6)-173&/D#F+(38).07ED)2<7G3%0B+.4?
@r8904
GTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAATCACTGGCTTTTTT
+
+'(%$"%&*))#&$!)*%*('"$'&##+*%+%#$'&$*'+')'!%(#!&'*%+$!"%!($')
@r8905
TNAAAANANCCATNNNNTNNNGCNCCCACTTNCNTNNNGNNCNTTNANNNANNNAANNNNNTTTCCNNNANGCACTNNNANNNNNNNTNANGCNNCANNCAGNNGCCANNNGNNNGNNNGTNNNTGCNTATGNNATNANTTGTNTNTNACGNNTANNNTGNAANAACNGAATNGCATGNAGCCNNNNNTCTACNNNGCTTCATCN
+
##!###$$"!!##$!"#$""""#!####!$$$#!$!##!!!#$$#!!#!!$!"#"#!##!$"##$!$"$"#$##$#!!"$$#"""$!$$#$"##$!$"!"$$!"$!$$!!"""!#!!$$$$!"#$"$"!""$##!#$"$$#"!"###"$#!$$$$"!##$$!!!$"""#"#$"!$#!$"#!#""""$"$!"""""##"$""$##$
@r8906
AATTNCACCAATCCAGCCGGTCAGCCTTTCCCGCTGCTCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGTGGCGGCATACATCGCCTTCACAATGGCGCTCTGCAGCTGCGTGTTCTGCAGCGTGTCGAGCATCTTCATCTGCTCCATCACGCCGTAAAACACATTTGCACCGCGAGTCTGTCCC
+
0$(?'/-(7+B14,D;?.'5C,H7!*3#ED46048*8#+>>ED7C1+4@1(!+;-C.H:=G0+F2/!9G3@",!D+H.*1,:G$:?9)..F>43*F'@>6"!9#<4@+';FBB;B)<2&?5-.2?,*,02<?-'*!$2=-4>EB)9#>2.(7+EA91<E9:56:.47/2>@H%7'C)>,@DH#BDG4B=81-';=!*H<H42>!C.=',%F*H.F5A
@r8907
GNCNCGTCANGTTGAATGGCATGGTCTCTGGCTGGATGCAGAAACCTGGAAGTGTGTGTTTACCGCA
+
!'($*%)+)!%!+%#**)"##(%!""+)!'"&(&)**##+!)&'%+#'!%$!+')%*($%'!*#+$'
@r8908
ATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAA
+
+'D;B);D;@B1:66#28,:D<=7<H2-85%360:DE2;D?"4&D,%$(#.64DF;2*+;H=
@r8909
GCACATCAGCAAAACGCTATTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAAGCA
+
0,.A7=B.F9=8=*00696A9:20.3$&8CE;,A(8B/>H!(94#4F!%/8#9'C-89=6GAB*D1;H))1=#
@r8910
CGCAGGTACAGCAGGTANCGCAGAACATCANCGGTGTGTTCAGCCAGNTACTGGCAACTTTCCCGGCGAGCCTGGCTAACCGTGACCAGAACGAAGTGAACGNAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAAACGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGA
+
;54-C.-@%/$!7?#D#A$$*.(168@2.&&45#>C(<&>A8FA+$8(:330?B503=*$8D9*::"F,&34$F0>8501/D@+'F3,>*A'.BB!=!@D:4@DCG/G05G,*#"6'=<"1!145!14E@E8@9,6#6A!:9E)5@:B9*36A(3C;D3*%;C)+=3E"4!"71126/0$C22-:?14/7A1>F:
@r8911
TTTTACTGCTTCGGCCTGTGACNGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCAGGGCGATCAGCAGAGTGTTAATCTCCTGCAT
+
:2D!'275"0??=+<-/3/FB2,%(AE%7)FB+&E&@<*D>;G+E!*4.<H&4;&(:-F&H:E'F6'6D>%766:;H<D21",6=-AD39#EF30@&#*&8"!!E-GB/?A5@&@-"5BD#:6B/GC<D@+G
@r8912
GCGGTCCGGCTGTCGCNGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAANGCCTGAGCGGTTGTAAGTTNCGC
+
1#8D99EH>*?19,<0.E5%@DF:H03%3+F82+2'94@3$;A>CE%A1:5D".$:("/9+2;4HBG<.%9%:$EC9?@84#:<"@#<'>B4
@r8913
CAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGAT
+
8,C9E6A1?.4DC97%@<B7FA97H!#DA)G17*4!>7>@.*;/*<%
@r8914
TGGTACAGCAAGCCTGGCGAACGCGGCATAACATGCAGTGGACGCCAGAAAATTAAGGGAAAATCGATTCCTCTTATCTAGTTACTTAGATATTGGCCTT
+
7/6(<F$/FB4+D2*5+$-A;#5>B1;B:>-?*4?64">6%2C9),));3*E:+-+FF$-=0"G.5HH;D'D(@.2C%)6+"'2D'9=8=G$>80@!(E%
@r8915
GAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCTGTACCAGCCGGGGGCAGGCACACC
+
11&#4B*+<+,.5,@9G?--+*-+'C1+46=(&'@C55'AF>E%:A@,+>.**C;0F:H8,C@:HH'71>84C.,A$8(H(-"9)-EE!-)D>!:+1@/7C*%8+)=B88,>+!.(*8!
@r8916
TCCTTCCCGTTCTTCCCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCTTCGATAACCAGAAGACCTGCCCGTGCCATTTTAGCCGCGTCGCCTGATTTATGCTGGTTACTGTTGCGCCTGTTAGCGCGGCAACGTCCGGCGNACAGAAGCTATTATGCGTCCCCAGGTAATGAATAATTGCCTCTTTGCCCGTC
+
/=A)C?9.&)<@"5("""613E5?B)3:/F'.46E"#"@",C.'&/A=DB7E2EE?+;H(G%?*"6:*6;/6$?@D.A"6"?B!(#71+D.-D+$<#>76&,E;=4!:&5ABB2*3H-H*<34@)(?<;$4E*"'<4-%&".>!8BG$7H&=$*E3H$D#4$89'84BH03#'=D*)H@===#;DGG@B.9<11(7#%>,"E$E
@r8917
AAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGA
+
40><@)7AF62GA#*!3)=;0!7GB&)!/C03CH*;.<8,"/"F
@r8918
CANGTNACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTT
+
))!**!&(*+(&!'$)&"%*++)"(""##%+#(('*"''%)%&$%#"&)()#
@r8919
CTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTG
+
G&8!*(9:83B6%D=7CH!5@"F-D7GD4>.1.*(+#7@0.@:'H;A.75#*=B4G3?
@r8920
NGCATCGTATTGTAGTTTTCCATATTTAGCTTTCTGCTTCCTTT
+
&+%''(*&!(%+("!%)*&((('!&&'%%$+"")&%&%"'+$!+
@r8921
GCGAAAAGATTTAGACTGTGAATTGTTTTATTCTGAACTAAAACGTCACAACGTCTCACATTATATTTACTATCTANCCACAGATAATATTCACATCGTGTTAGAAAACGATAACACCGTGTTAATAAAAGGACTTAAAAAGGTTGTAAATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAGAGAAATCACATTTCAGCAATACAGGGAAAATCTTGCTAAAGCAGGAG
+
>!0:5(@F'C+6!H(1#>(@D9>F(52,-;(.9B/A@2.9?3G+HH>$"E7!382)C@)'<(G65$7B-D685-7):C('*E>0.53A)?BC"$<3E*/<D72=?B6>?,BG7.)-%2=D27@021@@()#*=3)96"8&0">"E&'(63.A>56E1DD:EF;8?!()&?1>6-9-+0BE+)2H.A!<<!&@%6'+-;&;=<)&%%G>+-C))&C%F;&46(G7E0:4!&F+@$"/6E7)''-;7;EF"'*$E6<%.
@r8922
ATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGNGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCTGTCAGTCAGTGCGTGAAGCCACCA
+
E8(@0=0)1<-'#F*&1%7;HH&)"%$"+A'G;4A@'>(&(7,?1(D>&$#@CD@#@?'G':3$ECF.G+)/"H(9BF#AG&-4!0@F<.+0D5GA5;&%DC/."?@*0G<6/&,.?"07'E!>CC$F)@;'G'(EB,AG,%7068><*1&23'<*8EA(
@r8923
AGACCCAACCAAACCAATCGTAGTNNCCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTG
+
09C(9;B/4%=G:H%253:?;-?/!F)8(H=-=7DDD>;5#=,F=@HC*(D29"25=4C3(>AHC*/G(3)"9"10>,@,B*8H2CD!?H'"05('$;?!+4'(%#:A(H@A@378H&9?"F+!)+*8DG34++>56.
@r8924
TTTTTTCATAAATTGCTTTAAGGCGACGTGCGTCCTCAAGCTGCTCTTGTGTTAATGGTTTCTTTTTTGTGCTCATACGTTAAATCTATCACCGCAAGGGATAAATATCTAACACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTTGTATGGAACAACGCATAACGCTGAAAGATTATGCAATGCGCTTTGGGCAAACCAAGA
+
=-H<4H$D4$B&1=:?D-">HC&;E7!;?37&#;9?4+H;=3G66*$<*FA1,38.%D2>('*D:C37!<(#(!+2-:>!)9">!"H3)%6D>?24A#*9G/%@+*6G5$(7-4"8A&(8A)G(@>-!"1:8(1*>H0H#H:CG$+7#624?05<AC@4D/&,%H'<D,94"DB('5;C=4)G(-7;@89&#"))/BB8>3!-A?)!"42736;5"C2$:H%,1F%C45<5
@r8925
TCGCCGTCAAAGTGCGGCCCGTTANCCACGATGGCCTCTTTTTCCGGCACATGCTGNACGGCGGTGATGGCATACGTGCCG
+
:'6;:1F?;>H;0)!<C@AD2*<F985458*?(1#/#DC$?.?)47'=':F,D.A2-;'.95)F0&26#&40G<+(?HC1B
@r8926
TGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGA
+
F%E":(8#F0(B&D?E8+&;=G3D9.1.B+GG25(@:--.
@r8927
GGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCT
+
,F8-'4#<3,(<1?;!#-)D!-B;-"9>3G!:C(!.#)"/,4-%7!EA-550H
@r8928
GCACCGGCAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTC
+
4;CEF8-*D2HH>65<=9C=F%G/B*.=2$$6)(7.)9;++=%6&*
@r8929
ACCACGAAGCCGCACGACTCCGCAGGCGCACATCGCCGGGCGTGCTAGCCAGAATCGCTGATTCTGTCTGTGTCATGGGATTTACTGCGAAAGTTTGTTAATGGAAAGGAAGCCGCC
+
7(>*',;"'*9-)#1(E/&>F0DC:"-H,9$A1,B6:<B4CE166,0$$>>39G"@B'/F?.,57=29H:9EH;9-#8>?C!68G&2-A4?-:(%1F5:D-@/3@-8:CC6*FD2+A
@r8930
GACGAGCAAAGAAACCTTTACCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCAT
+
G3&4C4A()9EH"94+AE>=:H8:3>H;-)/84?=84/;*@;-9&0!;DF94'!=%*>
@r8931
NCAGCACCTGATATTCCCCGCTGTCTGCAGTGACTTCTGCGGTCAGGTGCTGCACC
+
#HG:85"%#"2:"#G":DE2>0&@''E7.,AD'C='2))@"-(;=62)"(7;F*08
@r8932
CCTGAACCAGTAAAACAACTTCCTGTCATGGGCGGTAGACCTCTAAATCGTGCACAGGCTCTGGCGAAGA
+
1'H"8$@$,A)=65?8D&F/58:&>=0$E;9FH-G(%:2E#0-=?6D&<(CC;#/9-9=H?9C/5"2>?@
@r8933
AAGCTATTAAATATTGCTAACAGGTATCGTTTGGAGGCAGGGAAGCACTTGAGTGAAGTGATTACTCAA
+
<0**7@3#,&?!=&8424B6;(2"E/!&:86:57@!C#05+.,;(1)DGFGC;<);>)(>H/F*#@E?D
@r8934
CTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTG
+
@;.F$:8?G0?>'#G">&3.&#189@9*,D*&%$18/">5B1-,>GA3*E(!BD=
@r8935
TATTCTTGTTCTCTGGTCAAATTATATAGTTGGAAAACAAGGATGCATATATGAATGAACGATGC
+
5-+??0C'/)5+%F&9B%::-H5BF*=",74A;EAA1'E!&-"=*.$*#%1%C84/E6E&,H!0B
@r8936
ACCNGGAGTTCCGGAAACGAAATTTGCATATACCCANTGCTCAAGAAAAAAAATGTCCTTGTCGATATAGGGATGAATCGCTTGGTGTACCTCATCTACTGCGAAAACTTGACCTT
+
):3-0&50*GB8($G2=B::7-5D),$?2BB326@25:"<%>2$A:77:A2BG>>023>:,<$*&3*/HA%=B.1"DC'!*@9!"F842C!3><,@B$**,'7E7E<);-+(%)-=
@r8937
TNNTTCAGCGTATTCAGTGCGTCAGGNGACGCGTCGATAACATCTGCAATCGCGGCCAG
+
*!!ED=>3GF03%"H?63G<56):%>4+.%7*!#17"&0GDA2!25H%E<#A?BB.6(9
@r8938
CATTAANGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGNGAAACAAAAACGGGGTTTACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACG
+
$()"%+"*$$$+)#)$%)+''+!*%#%+"*#*+!*(#%("##'&*&!)#"+#&&#!!++*#*"'&)&!)'+'))'$*)$("(!%$&!'*&*"!#!*+")!%*!''&#"*'')+*&"$"*%+""*('**)#)'
@r8939
CATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCG
+
7.H;:;##F1E9-+F3?>GE13?;4!@@.B5?&4:)3A**A11D$C&:/0B=F>
@r8940
AATAATGCCCCNNAACAGACAGAGGACGCNGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAAGCTGAGTTTTGCCCTGAAACTGGCGCGTGAGATGGGGCGACCCGACTGGCGTGCCATGCTTGCCGGGATGTCATCCACGGAGTATGCCGACTGGCACCGCTTTTACAGTACC
+
AAD1B+."1!9@"EA>*(!@G9G@8="95@0A5-/E$4")F*)07B!@D?479>'0H?*BD'06+>)G(A(>@(HA?,A6@C/%#&1<F6>3&)8&!H8H??;H*'5?D,G53D"'$)6?-.0@2F1.-<2<D1.AE;G>',F.1,(4FFH6F'0&5/%7"(G-1+0G$E<.CD"4*5!%54G&*
@r8941
NTTATTGCTACACCACTGCGTGCATCGAGTAAGTCGCTTAATGTTCGTAAAAAAGCAGA
+
"2ED63?11?#125,<=5;=/D#A2<*A"<+H!;)??<3,G7D*@F'+=G7(!*C)=%-
@r8942
TCGGGATCACCCGGAACAGCCCATGTTTTTTCGAGCGTTC
+
*$->75A$)G:"061!H0AE0/.!06!G53%&D$>@D&+"
@r8943
TAATATCCGGATGGGCAGGATGACGCCGGACAGCACCANAGACCAGCTGCAGAACAAAACGCTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGC
+
0#3A:!.8'/68%;:)<?19DE#F02F<;1A5:"AH88A4A<F*31$0/:2DA<#F;A+60/9@H/-:",=,H#D7:A>=@FA6@,147@93'"6<=#/";0$-3.6!>02)0>6%EF>A/>(,B$.$%>425'2H"1)8D;.=&':E)74:A6*+B'F3/
@r8944
AANNATNGTGCNTGNNTTTTAACCACATCAGGCTCGGTNGTTCTCGTGTACCCCTACAGCGTGAAATCGGATAAACTATTACAACCCCTACAGTTTGACGAGNATAGAAATGGATCCACTCGTTCTTCTCGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGGGTTGGACTTCTGCTTTTAAGCCCAGATAACTGGCCTGAATATGTTAANGAGAGA
+
&"$#*'$%*#%#)*"")++)*##"*+(%'"#+"&(*%+&%#+%&*")+*)%*+!'(&!$&"(((+()$$*)+$%$*"!"+($("*"()$%(((!(""$+)(%""%"%))&'%"%$!'"#%++#&*%%+#$)$"!+*#'"&"%"#)%(!((&&%*(#+&!&#(**(*"%)+&+*%%)&&%*'''%(&!'%!&(+')'$#&*$*'&''+!(&($&+()&#%&%$%))+('%))"*!%$&'"$'
@r8945
AACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGT
+
A%1!,8?89@8F$/8;/.=F@+DCC?+8"9%0!H/%5.D;*E!C>#@795D/HF4/94D8&*(>29=63AD&D+
@r8946
GGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAA
+
0<7<24#-'FEF>0&B7>!%+8>)1"7&%@D#B6H8-C!!"/.'"?
@r8947
CCATACAACCTCCTTAGTACATGCAAACATTATCACCGCCAGAGGTAAAATAGTCAACACGCACGGTGTTAGATATTTATCCCTTGCGGTGATAGATTTAACGTATGAGCACAA
+
959@@C9C!$F48!)?4C31:D$F*#"(8?12>+,B=;H#:.(>-3A/0%C60-!!;E2&444G'2;EH.-+A"A%B#!$)&40286(HF.",E,231E./;;$#,4CAG-6A'
@r8948
AAACTNATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACANCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAGCTTGGCTTGGAGCCAGTTGGTGNGGTCATGGANTTACCTTCAACCTCAAGCCANAATGCAGAATCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGTGAGAACATCCCTGCCTGAACATGAGAAAAAACAG
+
,9/#=;6D6?&.A+,F78!6,2.5D91+"64:3>216?5AG!A!=-$A$1>4@,CBF>EBB9()@+#9"9>0)#%A!,=);4B6#9&#D+G()258C4@<;++-8)03;/8!>5/DH!+F@=.1;?4>BE)8=+&/></H&2@,,!>H;-$?A@7D4CD2%';%>=?$;7?4.-,10!-00!H?4&G/CC051H%E,(47:=0%!0B1*)*$95!:E>5F4GF705<F%2)#820><42&)@"2G:,*CC*=!&G;<
@r8949
CNGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGANACGGGTATTGGCGNTATATGGAGTTAAAAGATGACCATCTACATTACTGAGCTAATAACAGGCCTGCTGGNAATCG
+
*"(+%++"&'(***!#'(!&+)%%"$(&$(*")*$*$*&"*'$+**"'+%(%+)(##*##+!%$!$!$+$*$+%$"$*&&+&$%&!+$+(&)!($*(#()(!%)!+#((&"(&*
@r8950
GAACTACAGGCTGACAGTCCGGGCGGTAAATGCGTGGGGGCAGCAGG
+
G$&CE:#)$CFE7!,B$.*.>>1.03H-H35C-!C*/<5AB!;F(,C
@r8951
TGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGNGGTGATTAACAACGACGGAACGAACGGGCAGATAGGTCCGGCTGCTCTGAAGGCG
+
(:.8=7;/#+7$G.G8-$E%":E=9(,7>GB0#(C&,$CDC>C99A4<A07(<&/!1?<(%'H<52+,&=(,/25:(1")%A,%+0GE.H,3
@r8952
NNATNATTTTCATAACGCTTTTCTAATTTAACCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGTCCTGTCGTAGGTAAATAACTGACCTGTCGAGCT
+
&"#"!C:3B=+370'D0*8/@457:*=?$8;?;!6=."E>)C+C<FG?F%$*%F>;"(3"E*C-0(E'09&DFA!=/@903=3,>>;@'*38><!H*5&#B,B<<$06C,2H8
@r8953
ATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATGTGGATAAATGGGCGCTGTATGTCATCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACNGA
+
20,D,8A5D>73'H5-HH<G.3;=A(3<:;D/-,4??6=(H"546;F"%(->E:,1!-(<$G:5%2?;H:8>9*=7F2:5%==#5!,D000+:4&7%,'<6AB$65;E5+(/E<9G/&E9-8#%F;5
@r8954
AGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGACGTGCTGANGTCCCNCCCGGCAA
+
*(=62>,)B%<D>=G>;46+29!-4G%6=D1D+*D>D;44#*7-)BF&.C3539$1"A,
@r8955
CTGTTGGTGCGGTCATGGAATTACCTTCAACCTCAAGCCAGAATGCAGAANCACTGGCTTTTTTGGTTGTGCTTACCCATCTCTCCGCATCACCTTTGGTAAAGGTTCTAAGCTCAGGCGAGAACATCCCTGCCTGAACATGAGAAAAAACAGGGTACTCATACTCACTTCTAAGTGACGGCTGCATANTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTAAATTCTTCAACGCTAACTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATTAAATAAAGCACCAACGCCTGACTGCC
+
3-E5GFB.9081)"%.C0>:0=-5(%G=6,3<+2E):/F<.8!;&1F6;-6&&"0435HC);88@;'H/@8<7>(19'D8+!2@H;#5-6%@;3$/>AH)-G'9)'+;4)-3!=<;-76&5B.#D-*@5G2+F!A(HGD7,$.FDF=?G0';=*:G&<,;58(!/6,%8#'GA>9,!4%/39!*%198;@:12-2&$D<F:G;+,F>>,,?.+(<-(HA+?*'=DE?><3"G;E=2-+>?<>.->0G1;C,<+G?-))!A/"<0;G>4/E4%&GH;!FB5*"8198DB9B,/B#2<G,;DG!(A=81624,B!=(C$%A93%?"$&B'-2@8<;8A
@r8956
AACCAATCGAGTCAGTACCGATGTAGCCTATAAACACGCTCGTTATATAAGCGAGATTGCTACTTAGTCCGGCGAAGTCGAGAAGGGCACGAATGAACCAGGCGATAATGGCGCACATCGTTGCGTCGATTACTGTTTTTGTAAACGCACCGCCATTATATCTGCCGCGAAGGTACGCCATTGCAAACGCAAGGATTGCCCCGATGCCTTGTACCTTTGC
+
#.(11?3):-+,/&5ED.31<>BF>$:+G/'%EF,*76%:8*H@'?')6<@68*37$H3%F34>!6F(1:>!7+54.8&)26C>=<$52F*;;;:176-2)&;?9AF*12''1/"@>8'G;G;=9#3+<;5%8'EC!G>@2H;.7E>+1ED67D'BC'A4"?F#AH'*C5GH$<,0/C$@C=H*$?D:#";@*BG31>#F'7(3A587%0(7((F1.-39
@r8957
TTNGATNTTTGCAATGATTCTTATCAGAAACCATATAGTAAATTAGTTACACAGGAA
+
05*>&/@?D?0!CD1.-0512;585%3<,&/,5<#G&=)*:!2C%*C<?*9.!D)51
@r8958
NTCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAAGT
+
18"6H0:##G8076,7#6DH13;F.06;G<HD?%#HE&#5
@r8959
TCAGAACGGGAAGCCACGGAACAGCGCCTGAAGGNACAGTATGGCGATAATCCGCTGGCGCTGAATAACGTCATGTCAGAGCAGAAAAAGACCTGGGCGGCTGAAGAC
+
#?&/6BG6?!7B!731A*.;%'=/9G<61<;6147#)4(>DGG1AH$<"5089(7G6(9"-"E1F9HF3C%H&=#.64$C*B-+<G%-54-EH(.).)-7.=84G&=7
@r8960
GCTTACGATAACGTAAGGAATTATTACTATGTAAACACCAGGCATGATT
+
@=6B::H2#7C>@,'6<)#3HFF=2EC5"#C:)B2E'$2"G50@B$#:,
@r8961
NTCGGCCAGCGTGGTGCTCTGGGAAATCGNCCTGACAGAGGTCGGTGGAGAACGTTATTTTTTGTGTAATGAGTAGAACNAAAAAGGTGAGCCGGTCACCTGGCA
+
!E%4H+4,.=D6,#'?;E!9+*.)+%H;H=<&"%G+*0+<7H<)**45EG2('/B!33G#!.,.B;$G)9FD/DE'C=.2/B=0)(G?G>5+$'*%2*.F$F.53
@r8962
NAGCTTCAGCTCCCATACGCTGTATTCAGCAACACNGTCAGGAACACGGNTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGT
+
!FC36*6H256",3@6/=&>A+"5$;<4AG.C/4,G#%8H0)BB3&'0>(AC=4;/H6C:#"91'-!D"62$H75=G79#=)EG%*<<=#A**<%F765CDH.-2@38#0!@>4)B19+*A"86'";5F$7=B,B4E"
@r8963
GCATCCAGTGCATCACGCATGACGGTGATCGCATCGGTGCTGTTAACAAGTTCATCAGCC
+
B2*0/13?;9?,*0/,#%*CFC@BF;A=A6B(9+,F;,0C-=D.+5%=2@&>":?;0(&B
@r8964
GACGGATAATATTTATTGCTTCTCTTGAGCGTANGACTTTCNACATGCAGGATTTTGGAACCTCTT
+
(13$E!G2&57"CB7.8H5H7C>F:DH>,.,72@*-(C&$C?.="0<9*<5:!6(H;"6,=EF:D%
@r8965
AAACGTCTGTTGAGCACATCCCGTAATAAGCAGCGCCAGCGCAGTAGCGAGTAGCATTTTTTTCATGGTGTTATTCCCGATGCTTTTTGAAGTTCGCAGAATCGTATGTGTAGAAAATTTAACAAACCCTAAACAATGAGTTGAAATTTCATATTGTTAAT
+
?:-7=+F0EB('5C!230:$30!*C)-%'9==.&>,!$:)&G/(AC<676(:7/"BD!C+57%?D<6,GH/E%G*=8,<1>4;7:-')D>1,4>?6&G<CG9AEHD:0G/2;2&)+96;<7)<E3;$+40.1"85#*&+B%B&,#B0));,8/A:!*="C$
@r8966
CAGAGCGCCATTGTGAAGGCTATGTATGCCGCCACTATTGAGAGTGAGCTGGATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGTGTATTACGCCGCAGCGCCGGTCCGGCTGGGAGGCGNAATAGTACCGCACCTGATGGCGGGTGACTCACTGAACCTGCAGACGGCTCAGGATACGGATAACGGCTACTCCGTGTTTGAACAGTCACTGCTGCGGTATATCGCTGCCGGGCTGGGTGTCNCGTATGAGCAGCTTTCCCGGAATTACGCCCAGANGAGCTACTCCACGGCACGGG
+
+@0&=-1.,)&=&,(=GHC3:H&%395-43&7;A1/9H"+.*C$?-3!@(BF@&4E?+.A(BB.D3&*2G6/0G"B(83*#)4,"5>#/GF31E>,/5=)46B4?$4G(H/<1-4!C<$87B:GF)-1'DA!4);B1"/$B48:;G0!4?G"?$<7)7*"BH38H?F,*A3;GA1(=?*)8BDD"AD*B63%H<,AF%@HDG/&*@$E8@#-,.E.F(#@"$*F)8>'@-A59F*/6)-EH;);(D?%>F565?;GEF2!G3@,5H16"891@8:":(321!=E2H3"/@5&?>"9>8>6<*!E/<CF"5!-=>73G$#D9;2<3'AB$8:C.(,CD+#21F-AG)(H</EE
@r8967
ACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGA
+
.172%2B#10;2?'6+=0A=;89BD:4(1CBDB/&H?&//F?6/89?#&=B@31
@r8968
GGTATCGCCTTCATTAAACCACGCCAGCAGCGNCTGCTGCCCCTGCTCTC
+
A7A'-:,!A:'@H+<$&2'21.!&8!-1CC:AC%*/8!2>/."4A8AG/6
@r8969
TATCCTCCCCGGTCATCACTGTGCTGCTCTTTTGCGACGCGGCGAACCCCAGGGAAGCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTNCTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCC
+
@7/*%9:)9##1,622(-8=".+?9@D;(A)304;,(588.<37B57#G8>-H33G%7@76'=):#9#HB('GCB1&:E<7>5?.8$54/$93<8H05C*)$029,!G/CE/,5E?-33;9<-=%#84BG24;1
@r8970
ACGGTCGGTCCTGCACGAACGTCAGCGTCTGCCCGTTCCATACCGGC
+
A38#@H'D>@8#A>A<(8<45'AF',5&,+A-/&27%#<>CE)#(/*
@r8971
CTCAAATCAACAGGCGCCGGACGCTAGCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTAACGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCNGCAGATTAAGGAGCGTGGCGC
+
E)?>'+#B),9B3AD?6#8@-;H>A.7)#)1F9$B3<#8A0%"6<!4A<5@&=+/)7FB?!+2A!G/?2!))C""54A)9E;HC;);.8.*.<,:/C472'//5FB646<4'EHC&$7"FF+5D$!662@9=&9C+?7'%7@
@r8972
TTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACATGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAAGAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGCATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAAC
+
,#"(/#B(.<=52!50C;5E45DB+93,@,)+$="%,)%58%2*@6$)!(/E#DC,7EH%B3?0#C6%;=0H#A7A+?6A4>D6FGA1=":%&@+*,$:6H?64:9822/;HF,/D913CDD$175@'8'A'5.=7?$&)?(3F>/B,+07;(03<AA.B"&D,2/AH>/7'C?#<*;3EBFH/,79&;$$,7,#C&%8$0-+$#0/>*H<C."B**598C::=>30B:%909<*&/9B3==>=B(@A%6+3,9836-)>&7&C8F#'26&*%
@r8973
TACGGTGGAAACGGTACTTGCCCTCTCTGTACAAAACATATAGATGATTAAACCCAATATTACATAACTATCCTCGCACTCGCGGGGATTTATTTNATCTGAACTCGCTACGGCGGGTTTTGTTTT
+
+()"$*$!'#%(*)$!()")(+$''!"(&%!++)$+&!""*#%"'*%%!)#"(+"'*%#+#$++$$(($))!$"$)%$)*#)!!!)!$$'")$"$#%#)"'(%*$+"(%&!$"$%#''(%(#*$+%
@r8974
GACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTG
+
32*><GD@3>A14,C8E;<>=,<!*>>C"(68*A$+-!=EDH890DH$"DA=;E,
@r8975
GNNNNGGCTGNCTGATANGANTGNGTTTGTNGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGGTAA
+
!)!"!&))&*"($*%'&"*"$''&*$'+(*%&&"*#%%(!#)**"(#*"')"%%%%%$#!!"'"#''($(!)#%"'%((*&#')#*!+%$(#))()(+*+&('"$%"
@r8976
GCACCTGCAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCCTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACG
+
+(5@*(;=>B;0<:;)!GABH6049*>$,>*#?A-"@+A-*32)75D%-#&729/91DC75)GE"!/02(*$"7$/F04D/(A?(@G&&F?="!8=;+EF0).2;>E$+>5DCA<>&(4@,<CD#8A*E#8+!'F?+&76H.1?F4*.6CF%8>?-/9HD0.><7)'3>)<553CCD++#3)D&A5-846652H#C(&F&
@r8977
ATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTATATCTGCGAAAAGACCGGGATTTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCA
+
%>!E-A4A$A-)*;@3?A$.#%:0&1'H7(E#AAAE<.B>@7,A:D!1"!H3/?&&G/=2B678A=78G,B'04!2B%-.,):4CD;#5+*'#'1!1$>762A#2-:9:6'<,C=?G?6G:G%'.27=<*"&E.,)$0@6>,-
@r8978
CAGNGNNATNCTGCCGGTTGACGGTTTTCCTCCATCGCACGCCGGGACCATCACCGTGTATGAAGATTCACAACCGGGGACGCTGAATGATTTTCTCTGTGCCATGNCGGAGGATGATGCCCGGCCGGAGGTGCTGCGTCGTCTTGAACTGATGGTGGAAGAGGTGGCGCGTAACGCGTCCGTGGTGGCACAGAGTACGGCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCNGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTGACTCAGCACGNGCCGCCAGCACGTCCGCCGGACAGTCTGCATCGTCCGCTCAGGAAGCGTCCTCCGGCGCAGAAGCNGCATCAGCAAAG
+
''&!&#!$"#%++#&'$*+%!''&+#)("+&+!")!+'(#!"$)$('$"#"!!!#$+$!+$$$$#('+*&""'!&**"+")%(%%$"++""&$)*#"&+&&#&())'(#("&%!"%&)'&&)*$)(%%*'*+'$#%"#"$(%'!%"*+'+#%++%""*%)$)""(&%"'+(&"!%*!$#!(##)'!"%)%&"#)&&+("+%)%*")"("!&!')&"#"+#(&""!("**)*+*!+'$")*+"%#)+%$$%+*!*)*"$$((&+"*%+)&+*$)%!+&#$)()'%%&+!'*$(*$%!*)&(!(#!&#&%#*'$*%%!$"%$#$%!!###'#+$&+"!"%'*!#()("'%+')*+$&*%!**!&"%$
@r8979
ATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAANTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAATGCCTATGGCTTCATTTGGATATCAGAGCTATGG
+
820G0";(>A#E1;5/B0>#>3.$71GC>8!0/GG60*7!+,F7>?<E<A80A/GD!2&31&5?)#09!&G0BB4E%8H$CF*>BD?4;*:@$&?8/E5D*5,+(%?3,,6!,#/1B:.8+&#)1"?51#,6=,B1*3H&H7(%'.>G.H3G"?5"2HG!F1>C#F34-21>!87<2"C9,<;&9H@51)29!%A<?0065&<3'D;;@)<9+1!)3&2@6&<"9&5>:(E)F6
@r8980
CTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATCATCTGAATCAAATATTCCTGATGTATCGATATC
+
,<8/F:2!'..8&9,E&"C@13-<G>)B#>$4'%)*A24+F&E1>"6A((*1/.3$)!@A-#+=6=*>?BFH(/<4)&A3&'59?G&A/5#;(6!)$F%AF%?7=3@$$GDG"5>:-%/52E*
@r8981
GGTCGCTGATGCAAAATGTTTTATGTGAAACCGCCTGNGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGCAGTTGCTGAGTGTGATCGATGCCA
+
7(8?5(/;+CF3.C/A$B==",FE=+,*BAF((?-22.-A05CG/3,"4>>!!8!%+F";!+=HB</9!/A7*5@42H+8E0+7(,G?%%:BHA)6,$',$<"C7"5D$;<?FCF6'9=/864"@1+!98-3>D>$GFF<3>1+8%A?(3D"<53>D
@r8982
CGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGCGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCAATATCATGCCGTTAATATGTTGCCATCCGTG
+
+#%%!$!!')""#!%%)#(+&#"##'!(+&)"**&!('&*"!#&*#*((*!&%+%"&%"&$#++#+$(+)#!)&*"$!&$'&+""#$$'$#"&*""($$"$%!$#%!%!")*"#"!$&#(!#%*$*+*)%%
@r8983
TCCATTCAAGAATCCCAAAGGGATATTTTCGATCGCTTGTTTCAGTTTCGTTCAG
+
(%')"*'#&+)*&"(#!"+)#)%+%*'&#$$%%&"+%&#&')*#"+"&&($"'+%
@r8984
GTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGCAGGATATCCGGCAGGAAACACTGAATGAATGCACCCGTGCGGAGC
+
/(@6-!A1?&;E5+?>E4+&#E;$9?G/*78$/<6-3B*),71C@;2E0=F-G/1#C+<!EA6E-/1HB4#.=5GB=;',FH
@r8985
GAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTTCCTGTCATGGGCG
+
G",)=!45!:F+:4/5@=+02D.BF!6H"++D;=@8*AB.:!'49H?%;.H$#<01A
@r8986
GCCTCTGCATCGTTCATTCATATATGCATCCTTGTTTTCCAACTATATAATTTGACCAGAGAACAAGAATAACCCGGCCTCAGCGCCGGGTTTTCTTTGCCTCACGATCGCCCC
+
+GG5.>'.ABB");A7G"?91/$$"H?<CD(A1:(F+D>(152.$A8/8*:2#<4!"##B::G'@277>=CCA'(=FF63H;7%A:9E:G+#$C7.E!4)E8+4)+98'C5!%)
@r8987
GTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTCCTGAACGAAAACCCCCCGCGATNGGCACATTGGCAGCTAATCCGGAATCGCACTTACGGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTGCTGATGTGCTCAGTATCACCGCCAGTGGTATTTATGTCAACACCGCCAGAGATAATTTATCACCGCAGATGGTTATCTGTATGTTTTTTATATGAATTTATTTTTTGCAGGGGGGCATTGTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATC
+
-,$-(&GE!6">!F',D,BD#:C!>*D)-/F(+:2(3$@4',32>=9F?)0*6E&!AA>@19:?($7-2''6?C$*DF==$#@+C'FE&"E-?:(67.&";8$@H,3+=+"BH."'(D$B";$&7>42=->6!B#4=@9(E6"0&9.+"2$8'<(/G3(B'!:6A<:A<=#=*>83%D6/$?4608@6#H&+@5>&883;(@2H2632(;CD1F<>77!=B<68D.0H'=%!)?DAF103$,D5!9C2%F8*G.6?(;7=,6+B+1#H">'"&A!'/E>@+4@'/60:?*@0=BH93<DGA!"E(/!505*D(#/*:>F;@#07<($+94G#6+3H.B&&3&@,F$.02-D808;&&(6C*6=H>9E8F,-DC#"1G0A'72*E"@'F!G):@:%3=
@r8988
CCGATGTTTGTGGCGCAGGGCAACCAGATATTCATGAACG
+
0F%$;5H/>**70";H('C(0==%EC-(-A/<B!+#98;'
@r8989
GACGGCTNCCCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCNANCGCAGTGTCACTGCGCGCCTGTGCNCTCTGTGGTGCTGCGGCCAGAAT
+
%(%*)!"&$+%)&()#'+''*)$+&"$!$+"$"(&*")!)'+*"+%##'&#)*&+#!+%(*#')(!"*+"*)*$%!$+)$+$"$"*#+#+%"+($)'+"&%
@r8990
GCNNNGANNNCGNTTGNTATCNANGCGTCACCTGACGCACTGAATACGCTGAATGAACTGGCCGCAGNGCTCGGGAAT
+
%&#%""((#$)%%!$%!&$()'"&%("+*#''*&!&$*%('%()(!)"')*''"!("$+"#!(&"('!'))*$+'#&'
@r8991
CCGTGATTTGTGCCNCGCATCATCCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAAT
+
*/05.G$D=,:=6=4=#$0>&*+?<D%6;8)*A9:;$-#&'&G/!/EGA-==E&;G2563?#G2GC!35DGG
@r8992
ACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAAT
+
9/#=@<<-3?G?:57G$3-#<!4#/:H'6,$9:(,@>)/:4$+?@,*9+7>*F0*D<2E9;--G89F?1;-.8#A-%A+>13',">9(+!%3*48#D%2?D<+<D"!?7.5+GD>(-"0<+@=&BD<>5D?&(?<!8H2H8A<72=.B1"8A1>/G")@"A)<9
@r8993
AGGCCAGCGAGGCAGATCTCCAGCCAGGAACTATTGAGTACGAACGCCATCGACTTACGCGTGCGCAGGCCGACNCACAGGAACTGAAGAATGCCAGAGACTCCGCTGAAGTGGTGGAAACCGCATT
+
"$2*8A6&,9C;6@'"9<=GD%D2E4.!B*,@-5):/H#%"#).;4(;H,5E;)7F;24=95*59(9/60CB2$CAHAC:9)/5FG28C&%>F&A;"B.#;4;$AGB-D7FG&/;9?".;.>A6,'&
@r8994
NGGGGNGNGNNTTGATGGCTGGTCCCGCATCATCAATGAAAACCAGCAGTTTGATGGCAT
+
(("#&"&"(&"+&'!#)#+)&#'()$!#))"))*!*+%"+&&'*((*"%*+#&*""*#")
@r8995
NAGANNAGCNATNANNTGTNNNGGCTNNNNANNNNACTNNNGNGNANNGACTNNNNGNCN
+
!$##$#$!!#$!!!!"$!!!!!##"!!"!"#!!$"$"#!$"$!$$#$!#"#$!"#!#!#"
@r8996
AAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCATTCGTG
+
C5=<G4-5A$/E?$+0)2'&C?;%7')80@8#DGE#A8<B88-058$F7<1
@r8997
NGAAATAAGAGTAGCCTTTGCCTCGCTATACATTTCTAAATCGCCTTGTTTTTCTATCGTATTGCGAGAATTTTTAGCCCAAGCCANTAATGGATCATTTTTCCATTTTTCAATAACATTATTGTTATACCAANTGTCATATCCTATAATC
+
%2EEF711-(1$>F!8CD8$)1/HH**3G+&)#4A+2)-)@!A5AC":.<B/9A?G=A6-9=2%<+@EG-#/**A+EF*;D$#2H7-,/*B&8)#*@B3*2@C7/=5/0!,$(6-&(F*BA,<=+;)BD-BCH+!FB(2*A1!@#(%7*"4
@r8998
CCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAA
+
F2E/;4*/2GFF$7;F(/G32EA!AA/G*>>4>?C$)==GFCHA,9<*123'2#&AC/!0E
@r8999
ACGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCC
+
#(;$4/>!'*$;2@A6<'A9,E3F!6-"%!86"2:=D*:H:E>+CH!"5
@r9000
AGAACACCTGTACCGCCTCGTTCGCCGCGCCATCATAAATCACCGCACCGTTCATCAGTACTTT
+
48(AG?,=%:"-2;?H-5)<1%DEE!$$1D<D39?8C2$,5'B"9>/=2*/$0:A-<:EH#3C#
@r9001
ACCAGGNTGATATTGATTCAGAGGTATAAAACGAATGAGTACTGCACTCGCAACGCTGGCTGGGAAGCTGGCTGAACGTGTCGGCATGGATTCTGTCGACCCACAGGAACTGATCACCACTCTT
+
;>501919#3C?CA$H;DE07##?6&B;-:1<1""%:0F'))6:-.$CE2/H7="&HB?3BG'B;*7>!>$>2B5?H7))'D=9@?6'>G#95;"GC78/40#"0("0A#>D-#"5C@2"05'2
@r9002
TGCTGAATTAAGCGAATACCGGAAGCAGAACCGGATCACCAAATG
+
*>D+2HAF+*@<8)!);9%A0=2%F-<2-G3/7(6F),F44?D*>
@r9003
TGGGAGTAAGCGTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAAC
+
2(-F<42/>&-5'%*A,9(A>4!"=,-?0#()<&C323#4;F!)!&6->25;7)=
@r9004
NATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCAGCAAAGATGAGGAGG
+
'DE><';)49!A065DE81G,2;*C=F&!&+F),"!?@''/?&?,&449?D!?<+23*"/5-.#)16#:8523
@r9005
AGCATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGNCGAATTTGCGGNGCTATTAGAGCTTATA
+
*(&+'#%'""*"*++#"##""%#$%+)(*#%#+*%%')!$#$$'%&*"(((#%)*(&&'*))!#+'$!(*&(''$++&%#&+!(")*&%)+$)'("$$()%
@r9006
NTATTTTTTGATGTTTGACATCTGTTCATATCCTCACAGATAAAAAATC
+
%H,F:3D09A@C4H3A"9E1!0<"8/6"8'.'0B>+6D"#G73B,"1$*
@r9007
AGTAAACAGAACAACAAAGCTGCCTGATAGTGGCCTTTATTTTTGG
+
#&+&&(''*$!#!++##!'*$&#*++"!#%$!*%!(*&!&!*"!)*
@r9008
CAAATCAANAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTGTGGGATGCCTACCGCAAGCAGCTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAG
+
32HH,.#%2,8/#90-788FDE@(<B/1;34360)2H=A:6#%(A?A,6G(G(.%62():75,?<(@5<+.91=AB759A<&":;;#975C;4H/FG(-"<G*9HF20F88=H+-?9FB5
@r9009
GTTCTTCAACCTCCCGGCGCAGCTTTTCGTTCAATTTCAGCATCCCTTTCGGCATACCATTTTANGACGGCGGCAGAGTCATAAAGCACCTCATTACCCTTGCCACCGCCTCCCAGAACGGGCATTCCCTGTTCCTGCCAGTTCTGAATGGTACGGATACTCGCACCGAAAATGTCAGCCAGCTNCTTTTTGTTGACTTC
+
G502;(&5G%#B5,6+-(C2<.#43EH+1)1H>6#+&D+1%'6<><&B"=-1=..*$/'G7G(01E8%%/;/!F+$.>F'%D;H"757+C=*",893HA4:C'"$5C4@&64=83B*)1'&H&0$>6>)7)>**!@/F+=<3#6?:0*2)@@?&)G67"1:)++',(-!EG)E!A$+D&$HC",=-B<4<E5.363E:(1
@r9010
NAATCAATATCAACCTGGTGGTGAGCAATGGTTTCAACCATGTACCGGATGTGNTCTGCCATGCGCTCCTGAAACCATCGTCATCAAACGCACGGGTAATGGA
+
!EA>6:@.596!%-:'&$7$F@H7.=D3=$$D*">EB*&+2/C9>5-($6;7!C++*4@'=-(96==0'C=,BD!A.$/:+DE++@G==>GF6G2<&#/F"(<
@r9011
TATAAGCGATTTAAGCTAAGAAAACGCATTAAGATGCGAAACGNTAAAGTGCGATCAGTAATTCA
+
@!4#C"-HG?/(,4D*=3+3%@=&%&@17-@H<+6),9&:H/@4F#A6>;>A)C%%G2?4/.+'A
@r9012
NNTNGACNGAGNNGNCCNNNCANCNNTNCNANTNGTGGNTANCGG
+
!###!!#$$$#!"#"$!$!""#"$#$#$!!""#$#$$#$!$#""$
@r9013
TCTGCTTCCTTTTGGATAACCCACTGNGATTCATGTTGCATGGTGCACTGTTTATACCAACGATATAGTCTATTAATGCATATATAGTATCGGCGAACGATTAGCTCTTCAGGCTTCTGAAGAAGCGTTTCAAGTACTAATAAGCCGATAGATAGCCACGGACTTCGTAGCCATTTTTCATAAGTGTTAACTTCCGCTCCTCGCTCATAACAGACATNCACTACAGTTATGGCGGAAAGGTATGCATGCTGAGTGTGGGGA
+
2(/+H.B1G7.+0:#%D?#587B=>D(#88H3B).F#((E?%0=(;G,15)22D?)).3&/B)?HA$";$),A3/9)"6#3B$>+:(1=!>G(.3$"E%.!8):A*G80=3(:->,2GEF7D'"+;C1E%?<%=?/E%',<!3.+E%%8*(.H',"--52EF3=&&F.<&,;51(@8/C$:'!2,("G8HD2('H7;41@5*8%A*C:C5BEH7@=F9A8=,*!092H95.%<2610.$((<+3==D95=-CF(2-E&;6&
@r9014
GGTTTTTACGTCAGATTCTTTTGGGATTGGCTTGGGTTTATTTCTGGTGCGTTTCGTTGGAAGGTATTTGCAGTTTTCGCAGATTATGTCGGTG
+
.;C4<5=$647)$D$?E%"+4=C;6),G2G!,8;H@,F076(E,),%5"!E(FE?7:,3%(1@<0$2H=0-!H21G8E)*A=7?3H4)D"<4&C
@r9015
ACGTCCTGCCACCGGAGAAACTAACGACATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACTCCAGAGCCAGTCTCGCTTCGTCTGAC
+
?,7!+1H,F-:C4)%G66"%8,7"&<(=%(;<?=.?=B+(8>381-?6!@E>%A.2;&*B@3%;C)H!+!,@#G#2)2+(%&:91,HH7972+"
@r9016
GTGAACGGCACCGTGAAGCGGTTCATCCCCTTCCGGCGTAGTNTGAAGTGGTTATAAATCTGCTCTTTCGCGGTATCCGTACCGATTTCGGTAAGGTAA
+
?+/7-6<,<5=#C(/(-"?#B"&46A?%5**8"?0$E59"7+@F@#6?*.0:=BH/:E;3-/B46%%166?6(9D6/.:65G7,0%DD<F0'C9:4F9%
@r9017
AAAGCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGACAGTACGTGGAAAACGGCGTCAAAAAGNACTT
+
,>>11>:=A=CF43/1&6!E2$G'0:7@:1=G;7D<B0HD/&D011,<,D<<A6+,>6:7>2*1/%?)-7<71!$3!9<'$5+-(1ABG
@r9018
CCGCCGGAGCCACCCTTGCAGCATGGGNGGCAGCCATTGGGGCCGCTGGTATGACCGGCATCCTGTTTTC
+
C#H6):C+*B(,6'.?4.B*H/0..=A34)>#7BE&:?2.3*2/-%?ED4:)@%6E40%F19<!$#9!05
@r9019
TACGCCTTTCCTGATAAGCAGAATGGCATNGTTCCGGTGGTGGGCGTTGATGGCTGGTCCCGC
+
+*")+*((%+(#*%)*%+)%#+!+)'%#(!#"$+'))*!*$&+'+#%#)**)++%'%""%$#%
@r9020
AACCGCCGGTGGCATAGCCGCGCATCAGCCGGTAAAGATTCCCCACGCCAATCTGGCTGGTTGCCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCNCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGACAATGGCGCTGCCGATACTCCCGAC
+
B'%=$-56E6"9;)>57*C@>*6.3895'/)(GCF@<F1%6E/!4,)$=0#/.?DFB;9;&*+$-3*9CH."A'F?-$>3$;9(91<6'=3%"*%/"G096#<2)"+A:#H@%C66<43=$!#E)@B38-*.;2!A,&*D8$9D@6C4?C$&+F"#'B/"4C?1+GF8)2,H>#</A9%HE/,8())+DF;.H(6C@4!@!8G2EH1B99-BC7&(:*F8E48.5!4=D<-$/).,C,59E0#=F0:
@r9021
CACCGCTTTGCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAGCGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGATCATACGTGGACTNGTCA
+
>#,5)1#.F;*6-=6E@E<BED8@0'.21#D?9-?.;,!#)$.8%;<'-(DFAA8?=3B<:BG@%*B-@(4%3H:+*@DH#*#;!#HCC?DF4.F;-.<(?9E3&(;)3F*-2)2@8?E%;#972;D&BB!D$8!6-3$DB+49C"?A-D-#30>8'@&F<*09+*CH<@5%&<%<EH*BCFED,8B%E7,0$/;'>18
@r9022
AGTCAGTANGGAACAGCAACCATTNCAGNAAGTTTATCCACAGTTAAAGGAACCAGCACACAGGGTATTGCTTATTTATCGAAAACGGACAGT
+
=)#.-F1%&70!&0,$G"$!:/"*E;25+5"D7E;.++F346),F%)>-5B&6=+1C+B3@B7B.@:';,176DF*&G,=/?G=1%:223"<&
@r9023
TTTTCGAGCGTTCATACACAATGGTCGGGTCAATCCCGCCAGTATCCCAGCAGATACGGGATATCGACATTTCTGCACCATTCCGGCGGGTATAGGTTTTAT
+
>'2*4!48C4#?<3@(3F139F,7?>#%+85F:18./&E=D&.F,1BFDGGG6=5=H&7<=05,,C;(G751+"0&+#1,)8*!C@./#9$?;%?D92%*$#
@r9024
NCGCATGTTTACCATGATGATTCGGGAAGGTGTGGCCATGCACGCCTTTAACGGTGAACNGTTCGTT
+
%(&)%#+(%'("#!!&("$$!&%'$("('$'!"'!!)')!"*"!(%&&$(&"(#)"%$&'&*%&&%)
@r9025
TGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAANGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGAC
+
GE70':6EF*&.A%.!>8'-1.HE*4B=G#9+'!.F".;&:9?=A%*FC<2003"?6+;=4'*')%<?<*7#7!&?!>@!@995?E+<BCA$#@1;18>$>.'2>D,+FG
@r9026
NATTTTTTACACGAATCAGATCCACGGAGGGATCATCAGCAGATTGTTCTTTATTCATTTTGTCGCTCCATGCGCTTGCTCTTCATCTAGCGGTTAAAATATTACTTCAAATCTTTCTGTATGAAGATTTGAGCACGTTGG
+
/=>"#)"*<5A&&*:A74!B:%6)6A55<GC-3!A0F)&*;*7G+4492$&H:G6C,:;>!92."3-(=42<.-B545(%..>%"?+!D6,$$C=5&D4@/!3#&AD9CD5-B>>C2B)E!,6D=0'E)?1,288F=*@/H
@r9027
TGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAAT
+
+<D:<0!(A/6@F&@"%5)=45"(44=6DF*H++G(<-G$6=2!"@G;1
@r9028
GNGNGTATTGCCGTTGCTGTCTTTGACGCACTTGCGGTGNCAGTCACTCCGGCCCGTGCGNAAGGTGGAC
+
#!&(+&*#'!)$'&(*&&%'($")"#!))')(#"%+#'''%+$+"%+)&$!'%***++()"($)**"+*%
@r9029
AATAATCTTTTCTTTTTTCTTTTGTAATAGTGTCTTTTGTGTCCCCCTGTTTTGAGGGATAGCAATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGNTGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTATTCCACCCNTAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTGGTCAGATCTGCGCCCGAATAAGCCTCAAGCAGCATATTTGATAGTCTGGC
+
@=<>D>+%&9?.,FF:61>3&*;+GB".D&+(81:/05!'3!D5&"7<.>H709H;'%:G#:DD'9?-$?">@&"D6&9?4-48+?)H7D*8<%,6C3";;1D>00C4-/6)/02.7#$"#=<E'-="*!,$*BC25&2F:!<B#'%7/);G+!!0*:$GA",2=@$";G0,HH-31B>)1?-$EF$$9&H5!1,,<19B86.0&(#,8&,,%&@,,-F!%*9$!'.;05/F>1*EFADD8'D;)G-3,25C;<&#9HD=,$!7;.+(.'?B0@)6CH$9:H6HE0&2%>(3>?5G<651#=02$'8B3+6GDD,%:?661"G7+?CH;7)D25A;1@C*H"G>*).$=352>#E$@E.+A(?3&@-(4F("@?%#2%$/HD?B>790
@r9030
CGATATCGAAGCCTACGCGCTGAACGCCAGCGGTGTGGTGAATATCATCGTGTTCGATCCGAGAGGCTGGGCGCTGTTCCGTTCCTTCAAAGCCGTCAAGGAGAAGCTGGATACCCGTCGTGGCTCTAATTCCGAGCTGGAGACCGCGGTGAAAGACCTGGGCAAANCGGTGTCCTATAAGGGGATGTATGGCGATGTGGCCATCGTCGTGTATTCCGGCCAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTGCCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTNCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCNGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATNCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGATGCTGGCTGACCCTGATGAGTTCGTGTCCNTACAACTGGCGTAATCATGNCCCTTCGGGGC
+
1.839:E+*<#$"?=+16&9;,.:<BB3""5'$D(%A&--4*6H'"G#*&/($#&4,E&87&3/GB4/0B7$;7)."222D>6#A-6C%89#&(4=%)#+'7<$(&@7@C,%+:1"(0#05'3"+225H6?;@E6&G-"$B/*!G:,>=/>;8G+%755E"F2&!69$8;,>;.FE)4E&2+#7:"8%"72!CFH=1:#-)59&255A@6"!=7!;#!5*4>5)0%490.%D9C=.52;0$CFAADD:$C2-!&E49$2!-*48<3:3#5E(HHB4@#1@GD8<HGCD#9+8/:$;03./0B+EG@/G)+4.@;A(E)*/*CE(-&"1B&E475,+!H:)&2)"$E.;;6B.9D94B?A-'E?=265&:G7'"%7:H>75B:,E0.C-!9:0-@/0,3G'D&C*C)/0A8B"/E0>&%1,*!%<9%!,<55A-6%:&*H8=406(9.4#9>)3G#+/1&@!4":!'40%?)&3)#..$&!%7'4:09((D=%*!-%:.
@r9031
TTTATGATGGCGCGGCGAACGAGGCGGTACAGGTGTTCTCCCGTATCGTTGACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACGCTTA
+
%)&+#&'")*"'')!(*)***)*#&#*$+"+"$()%"**&!&'*)'*#"!)!"&)+++#)#+%!$+!+#!"%'%)*'($!("$""""!'!(&&'$&$($
@r9032
AAATACTGCATACACTGCAGAACGTCAGCCGGNACGCGACATCACTCCG
+
:A+-<>81(*63G$<H=%0!$@B@-:9F/6495H!%F)(#15:>F;F+,
@r9033
CCAGACTCTTGTCATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGATTTTAT
+
9-,;HB)4%20=9/*$(5)@<=+5D*&D/;B"BE!3BFE660#)/D"?-B7'@.
@r9034
AACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTG
+
#EC>:F0/>4)8@G6.$3B57F?8)2&:@B(?:'FEFA@E((/A<!>*'0?))#2H+?;"*
@r9035
TCATGTCCGCCACATCCGGGGNAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCAAGCCCTGCCGCTTTCTGCATCAGCACATCATCTTCA
+
-+;B<.1HE3C:4#)FG,=(5,B9%1G':4D,0.FGAB)05A?7GA:80GE<6>#,>7B?+)1@.@&58:.G$#!>G0?3(E@9FD9(3"=8!E+0H5#(+(#:9-/
@r9036
ATAGGCGGGTTCAAGCATCAGCNGCTCATTAAAGGCCATGCTGGCAATATGCGGGAGATTACGCAGCNCTGCTGTCACTCTTCTCCT
+
6<5,4:-C/F5D441!D<3E*?58#)8%@%!G9>'A$<18?)/CD<<(/E8H$*E686!H4*:3F,79:%9@=D7,=$6;36<34-C
@r9037
ATTCGTGATATTCCGTCGCTGCTGGCGCNGGCCCCGTGGTATGGCAAAANGCACCGGGATAACAC
+
5:!.8H;F"5D:28(4(DH,E;B)AC8B@EEEE.:9&/%DFA#2'=$:7C%3"'(*@!;9>?)##
@r9038
CGATATGATCCTGATGCAGCTGNATGGCGTTGGCGGCATAGCCG
+
3.("7<@#$D$/F"=:6.B)AG(>C.E6=2A.>B..(D-735:5
@r9039
GTTTGAATTCACTTCCGGCGTGAATGTTACTGAATCNCCGATCATCTATCGCGACGAAAGTATGCGTACCGCCTGCTCTCCCGATGGTTTATGCAGTGACGGCAACGGCCTTGAACTGAAATGCC
+
%(:H>F7G+HFC%F2>!"(D*;@?#HB4E8'"?'-.+.B>6=*0C;+FG#'D.-53#;;H'<$,2?+$%36D3'$+=$$&0!0A)%<4H0%&+1F(H%#0)2/=98G/7;'8&>@*F8',;=/F=
@r9040
NCATGTTTACCAGTCCCGGAATTTGNGAGAGATAGACTTTCTCCGTGGTGAAGGGATAGCTCTCACGGAAAAAGAGACGCAGAAACAGCGGATCAAACTTAAATTTGTCCGCTGCTCATTTGCCGCCAGCAGTTGGGCGGTTGTGTACATCACATAAAAAAATNCCGTAAAAAAAGCCGCACAGGCGGCCTTTAGTGATGAAGGGTAAAGGATGCTGATTGCCGTTCCGGCAAACGCGGTCCGTTTTTTCGTCTCGTCGCTG
+
#9*#-<4/C)&A*@?&?3+B6='B35D",G+8396G0<FB:---(-7"?8BA$&<CB3+&-!@%1@6)!@H1>C0A$.$)!4#;.=89"5BDG<<'*H,BF'/!/+@/!H(1.*/,!DBCH6*D)@/088#-1?;0++)/??8&7<6+8$&==89)*39DB7=.4#E!2&*!22@>'31)("/E*F!D*EH#+"*!7>99/&;/@EG;D>?@?09G*2@:<5&?E@@/(8*3(6&?24$$+")EF4#*%H6D8/B#&,G(*(
@r9041
ATTAACTTGGCTGACGCCGCCTTGCCCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTGTGGTGATGTCTTCAAGTGGAGCATCAGGCAGACCCCTCCTTATTG
+
F844H!('8H,!4!B1A-22+@&*(@*)B,(H,>#-2"-<G&%)HF;C<>'$'(;=.='9(5E$H48/(+!+%<+(!#)$*"$,.;-F&H79-.533(BE<9,$E"E8:/(E
@r9042
AGTGCCTCGTCCATTTTTTCGATGAACTCCGGCACGATCTCGTCAAAACTCGCCATGTACTTTTCATCCCGCTCAATCACGACATAATGCAGGCCTTCACGCTTCATACGCGGGTCATAGTTGGCAAAGTACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCA
+
>B=%$3A;E'$:>EA97H-'AD$)@&@8B+B80#3%?&8'G88C#H++45*6BG;51'5A%(0/.!0#'E$8C8C5.,A'$825A.+:"F+A!30>>+82,9;#$D('=0E@)>&;5*509.;CB!!.H>GC7-F.*3'E#D4%=-!>%'"G%4.=!19A23G'?>@#H7/CFE9-H4
@r9043
ATACNGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATNCCGGACTGGCTGATGAACTTGTTAACAGCACCGAT
+
F"B(834)3('74*(=D'/&-,A)8>&56:C)>;?8A0BF%%.:9F4B46D)@/0?#8F:9'F8F1@2DD2%B<9.6
@r9044
CGCGAACGACGTCAGCGGAAGCACCACTATCTGGCAATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTCCCCGACGATTTTTGCCCTCAGGGTACCGTTTATCGTACAGTTTTCAGCTAT
+
65:D"9"48!8H.4A2-&041:H+%"-;#:HF5*,8E:G'-=HH');6,33=37>C8(1:51&H!6-,<%9G1,EC#!C-%AA39H!C--GE@G=C8.H)G'%";8D7@-8<EE(%5*20:/."C8*&AC<*@FE<H*796G(4=:H65+<,##7@?2"(04A@66G'3@37F&2&/E390<53($H$E*C4!3/
@r9045
NCGTGACGGTCACACCGTTATGTTCAAATGATTCGGTTTTCAGGCACANCGCTG
+
!+)"'$#"!((''+%)#&)"&*%+)%+%(*$%)"*+%+&&**'+&$$++&$)("
@r9046
CTGCTTCCGGTATTCGCTTAATTCAGCACAACGGAAAGAGCACNGGCTAAC
+
)D5,#@=D/8G7=,?('DB)%C#)132)=(75)CF6,B>+,"64?B1,-33
@r9047
CTCTGGTCGTCATACACTGAAATCATCGATGTGAAACAGTGCTNCCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGT
+
9"@6GB#EH7H)/4E1=1'9?E%F,1G=D@G.95A-$8"D7A'*+79@-1+5F--1E6A89";(5>90$.B<?>;>)68%-8):@8>1/C98->$4"F%=HA71
@r9048
GGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGACAGCCTGANTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGAGCAGAGTCACCGCGATT
+
,'7+.;4/-&,'1F28%:E11BGB3,(G;,;"$69%+G<38&2G"""*80?H>:*8A$@;6-<>+*B*):974?=,0()D@9;9/AH9>,@&06F9%@:5/2A#'907A.
@r9049
NNNATATTAATATCCATTTTTTATAAGCGTCGACGGCTTCACGAAACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGNCTGGATAGCCATAAGTGTTTGATCCATTCTTTGGGACTCC
+
$"$+)%+$(%)&#'()(&*(&''')+''!&(+*($$"(##$$*+!&$)#"'%"*"(%"$+$(%)$##'"'+*(%++*(&%'##*+(+#(%("$#!+#"""*&#!'%$*'")'$)*%%"""#'!"&$""
@r9050
GTGCCGATCTCCTGAGAAACCACGCGTGACCCCACGCGCATTCCCCCGTNCAGAACAGGCAGAACATTGCCCTGGGCAACCATGTTATACAGTGAGGAGAAATAGGTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAG
+
01)53A0(!CB<,==63;G=<C!4;,E(42!@%H+&2*G18G$#6!9-5?E;2?38!'GCBA*2H356?4F/G-E/>7(1@)!=CE(;7*%?;>0E;&9<F&0(:6CG1&8:G6F-A>GD&G55&!H"!-<=<%-:!A,3F)E:3@2*E'C,.F6H.@<$8F/D
@r9051
ATATAAAAAAGGTTGCCAAGGATATTATTTTTAACCCGTCACCTCAATTTTCAGACATT
+
,%,=)&43403&E$AH/D(-,G6@25A*0!5G4EG+)#6#1D,5=>D.1G*0&E4E5+D
@r9052
AATCNANCNANCNCNNNCNGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTNCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGATAATCGTGAAGA
+
'*&("*)&!()%!'(*!$$+(+'"(('+'$$"&"!#(*+)&(#*!!(#)"'%+(*%)#"*&!*""+'+!#$&!&!'*!)!*!$$$&%(!('!'%$))&+""%%))%%%'%*(+!!##))!&#%+&+)(+#*(&("*%"'(%
@r9053
TTTNGGGNGANNGAATTACACCACGTGGATTGGCATCAGAGC
+
#'&!((&#$$$&+$*(%)#&"#**)"'(*(%&#%#%$+)%"&
@r9054
TGCCGGGACCACCATGCGTGGGTTTATAAGGGGAGCGGTGACCCTTACGCGAATCCGCTTTCAGNCGTTGACTGGTCGCGTCTGGCAAAAGTTAAAGACCTG
+
@;2H""'>5E/619&H?98*2$/$0$("E)328)?F:A"@D.G4F!/&DG7=<6)FE!9.+D,(@:FA++(G+HA8(A4A7>4#:6!'A(%!E<#62%=,()
@r9055
CAGGCTGTCAGCCTTATGCTCGAACTGAACATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGACGGATATCACCACGATCAATCATAGGT
+
1(&0(62@0'49'445>+#8+9A9>$/4EG0@2DD)E#2#>E.2"?HE2F:@E"E"3%0#FG7A9%=-')?=H=&H.?1(*B>$D0C)D;4),D6>8>6&>$('(."::D:B
@r9056
GATATAGCCTGGTGGTTCAGGCGGCGCATTTTTATTGCTGTGTTGCGCTGTAATTCTTCTATTTCTGATGCTGAATCAATGATGTCTGCCATCTTTCATTAATCCCTGAACTGTTGGTTATTACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTTCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGGCAATTGTCATCGACGTTTTTATCCGGAAACTGCTGTC
+
>76@*)&!-,3."B?44"#2A9.)G'3:&$'"@F=<6&.!/:9""4?:)&C?9>/H4<7=9*A.81A"(,;'$(70?$EG8=F97<*2%%@D(/8!0%8G3CA4%<F>;H*4A'&@G)>%(<1C%",G>&B#*,$&?4$'2"0:9EC*3(HBH7@H?!,6>'8G8?52*.&,16G63)B708EE6DE6&8,<-<8=9;498>:"/.H'AE<09;5<;>A##4%290-0"?-$8=;?H?C"&0*(1&-/C8A-)H:?:E*/A7#+)$/'"A:C?9'.9C7'.B35"1=%<H8H4)=BA((>7"85<)<1>-5DD6'E'9*%.G1E@B/E+%:E/#""
@r9057
TAGATACCAGCAAATCCGAAGGCCAGACGGGCACACTGAATCATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGACCCGTGATTTCTCTGCCTT
+
0DD:/&*F6..4CF70C".,GB""%?#!+HG#;0+.5!G8%')E!6(/@9:&GBC8/G'>B+)4C.#D+$>70,&349H7:F2+(H910,HH%8#4@8.%!.?5!>
@r9058
GTTCATCCCTGAAAGGTGGCGGCAGCGTGCTTGTGGTGGGTAACCGTCGTATTCCCGGCGCGTTTATTCAGCA
+
CHD0368/4D*,6A*+"';81(:G-3<5&-.B/.9CH$%)-H7;.!2@2H%67#%2F<;EB&;F@H842=(A=
@r9059
TNGAANANANNNCGNTGACATGCTTGTTTCATCAGGTGAAAAATGTCCATTTTGTGGTGATATAGGACAGACAA
+
%(*%)(&#)$$!(*"*+!+)($!$)%'*"('%*'')$+'+%'!"+)$()%)"*$)$$'(+"!+*+)((&"(%$(
@r9060
CCGGAGAGGATGAATGACGCGACCGGAAGAACTTGCCGCTGCCCGTGCGGCACTGCATGACCTGATGACAGGTAAACGGGTGGCAAC
+
9H('B</A>GBG)F4;'#4;@?E;:*>:,;7:C3@EAC'>B(04?<!!(E*;!/'>AF(=D6<)A4)B,(#*9CC%0?'E>HG@*-C
@r9061
AACGGCAGCCACGNAGGCGACAGAGGCTGCGGGAAGTGCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCGNCGGCAATACGTGCAAAA
+
)()$&)*($&'%'!#%&+#*$"*$#%%"'**''*+$'*#"&)&)")#$"$%*"#$!'$%)#'+&#*&%'&)'#+%'#"*')!'#"($#%&*#"*
@r9062
GGGAACTGTGGGTTTAGTGGTTGTAAAAACACCTGACCGCTATCCCTGATCAGTTTCTTGAAGGTAAACTCATCACCCCCAAGTCTGGCTATGCAGAAATCACCTGGCTCAACAGCCTGCTCAGGGTCAACGAGAATTNACATTCCGTCAGTAAANCTTGGCTTGGAGCCTGTTGG
+
7G::,<#+/8D'?+->2!%?E*7)7'3!*%<C-*A4..F"A/F+>;E+::"H4C1%-'>&/$E6.53GH#!7',4"'C&"0A6EH!80!52F,/(-?.3=$)BB-)#),>A4<@>#@76'>=@$218!HB*'>HH45>A)?6@HF&:0G&,H'2E8/$1-C%#-8(B6+2CB5@#!
@r9063
CAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCACCAGTAACCAGCATAAATCAGGCGACGCGGNT
+
==H#B-($:>=5)@*3B1B;?.)!G0HD74083:">':E8")@(2EEF!-$19HH0+9)+"F"C)@(8D@#"!:!&%;4C9G46.)F/=4E76.A7305%
@r9064
GGNNGATTTACNGGAACCGGCGGCAAATATGAGCCAGCGGGGATTGTTCACCGTGGTGAGTTTGTCTTCACGAAGGAGGC
+
''#%)(&(&(&#+"!&(!'!&%"(!(*"+(!"%#'(*%!!!$$+*")%"#&$)(**&&'')&!$$%*'#%)&)')#%#%%
@r9065
CGNCCTCCACGGGTTCAAAAACGTGAATGAACGAGGCGCGCCCGCCGGGTAACT
+
2,6>'G:%!;HG)*;/EH1#,A"+5(/@A63>9-1HB5G&B&9*?6B'/B5F%"
@r9066
GCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCCTGGTTCAATCGTGCCCTTCTCCACTTCGCCG
+
*B!2+64"B0*G3F50?50%?5:H=(#*!65AF*E6;@G."7?72:6;D(;'H385@3,:4B!1!C1-*E$3177E-906'CFD
@r9067
CCCGTATCTGCTGGGATACTGGCGGGATTGACCCGACCATTGTGTATGAACGCTCGAAAAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGNCTACGGAAAGCCGGTGGCCAGCATGCCACGTAAGCGAAACA
+
-!"93<+!1!&>%)&4'*A3<5'-/<HCG1<$%6>G<6==/-@F<:@!B*:./!'7(+G*C:0'9)/9,9581)<1.06FHC'&3)!D2>A*F-EG&$6#?$0.*77#A>+C+H(D446AG9E1),!<5=F0)6D5!'1C9-)7
@r9068
AGAANTCGNGACGCNGGNGAAGCATGCCGGAGCAAATGAGAAAATCAGCCAGCAGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCNGTCTNCACAGGAGAAATCCCTGCTGGCGCATAAAGATGNGACGCTGGAGTACAAACGCCAGCTGGCTGCACTTGGCGACA
+
(&*&##&##')*)###(!+'&"+'#%)#+*+#%!%"$#&(+)*+#)("&*!"#!()%!'')#%'%+"%)%*)'&&#+!#"***")'(!%(#"!#%#(&#'(+''&"!##!("%#*'+*%*((!&$"$%((!"'*(*#&)%(&+")!'#!!&!*(('*()"%""!%)&'!#*'(("&!)')(+!%(+"!(!$+&#%*+$()"+%
@r9069
AACACATCGACCGTGCCGTTCGGGAAGCGGATTTTATAGGCACGGGTATCGCCTTCATTAAACCACGCCAGCAGCGCCTGCTGCCCCTGCTCTCCGGGCATCC
+
7&':H..C?2#H.+,G%AB'>5G7B46,DD.?;>"G507<;;$?,D/7)A,);*C%:$2-A75D01(2"@2>E<FH$G*9"H).(F7'31.;B3%7$''.9(B
@r9070
GCCTAGCANNCTCNGAAGATTTTTTCAGAGGGATCTANAATATGATGAAAGATAGAAAATTACNACGNTTATCGGAAGTGAACGAATACTTTTTATATNAGGAGG
+
$()(%#&$""')*"+*#+%$%'&&**$%"+$*&!(**'**+&!'*#)*'&'&"'%#*#$&&('#$'+!!&&%)*%&+'*%*"%%**$&*+%"*+'!)(%#+)!%&
@r9071
TTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCNAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGACGACTGGGGATTTGACGCAGACCNTTTCCATGAATTGGTAACACCATCGATTGTGCTG
+
GE96F-AE?82*.$#GG/35>2&D)$D8(D)A?)=$?'+<@%"$/,;4)*9%1;=%5?1+:10:064/#36$)=(F&D2+B7-$:*(G#/<5-HD'DFD$&/($B*B!37F=0B/=)454$0@58.%1%'4<*;7$23?5,(0&,A855%!#)+$D;;>/947C*@EDF%4.5F@B$-C75FA8&?3.>5%,":;<B<@"!C*""F9#B/9G/';*6H5CF"E(#*=6
@r9072
TTTTACCAATGGCTCAGGTTGCCATTTTGAAAGAAGTATTCGATCAAGTGCGA
+
;><4-!E582=G94><B(/.6/0/*%=,:<'8=71)>=G8<"?"%6<>08+A;
@r9073
GCAATCATTGCCGGCGTTCGTATTGCCCATTTATCGACATATTTCCCATCTTCCATTACA
+
4#D@4)54;8.4?+@42;%77G7E9)/";(9)!+9+CD%H+8H659C1B*.G53#C//0$
@r9074
CTTAGCGAGATTACAAAGTTACCTGTCAAACGGTGCAATGAAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAGNCGGCATGTT
+
@35>%60%C@@F8<C%*!0-?9H9E6#=@<-5$E;=5@G'<)2@<>=E@>0D'%;.69>5B69H-%%=$34;*F*BC3(%!1->,B9<+'(@<!.
@r9075
TTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCNGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCG
+
=/4!58B+?:)?'.5E,C1*/3<#F$A+!2?"4:F':)$-8&>C6E4G0(3((=*)6FG38<>+E/A$#3H*!+;DF-:++A10%@>6E0=<):<(=0"*;#<7EB"HC,7&H>99?/2!+.6)C/&>0:%@#
@r9076
GGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAANCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAG
+
717*#?A07#H>/A*7!&35A#;)#<E>E1?H0G).;G"#++1'(&%&/-$C%/<>1(8'28>;4#"<9(=;D2B-?
@r9077
ACTTTTGCCAGACGCGACCAGTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCGCTCCCCTTATAAACCCACGCAGGGTGGTCCCGGCACCTTTCAC
+
&,):/7+D+2?.21#+#HD<7;*1FD8!DHB6*>'<>,G?8HD#E$1?+6(<2%,*6=3'+)GB!<%C%>)F$?G1%-*1/(;D&A"H13B47>C*#75)
@r9078
CTCAGCAAATTAAGCNATGGTTTTAAACATAACCTTCTTAAAGCTATTCAGGATTTAGTAGTATGNCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCATGTGNGTTAAATGGTTTGCCAGAATTNTCAGATTTCCACTTTTCATTTAATAGAAAAAGT
+
'32#;&H#+&((%7<1'"',6,?<!/<=)A%-/32E<55-;"$!4+$CG=82C6/,7"D89BA2?>.-:@3(3-%HE-)*D73A+#BFAE124(A4='7*3!-:<G817D(2-F=EGG.5H6'*#"@B4H7(?/4.G8;5&-/)=1D;6)/3A2A%816#C(!D/H$HD5/F39%&<2(9H,0?!,.@>#AF%+(%.>';@1783.%7H-<-5$%>$H>
@r9079
AAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGA
+
#2"FD%A?-=.(3,008#$#:,.<G,H-*0,73*(>"%&G-CH+##&A3
@r9080
AGCAGGTCCGTGAAACGANGGAGCGCNGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTTGAATCCGG
+
;+#"G)A'(2=)><;3<>@.><.))>/'5*0#8+/1H>DH.C3:153<:46%+>476.6"11+?,9%92A#*48@2E:@
@r9081
GCCGTTGCCGAGGAAGCNGCACGACCGGCACCTGATGATGCGTTCGTTTCTGATGATTTT
+
-)%()<<AB%#749=BH6'&0,8:;A?<>G?D'F9-:81(-;/-G?D%!?8)7@C)FB>"
@r9082
NTGTTGAACCGCTCAGNCTGTGAGCATGAGCCCCCGTGTTATTCGTCGATTTGGTGCCGTAATCGAAACTGCCTGTTGTTTTCGTCCCGTAATCAAACGACGATGTGGTTTTCGTCCCCAAATCNGTACCGGNTGCACTGGCACTGTGGGTGTGCGACTTAATTTCATCCTGTTCCTGAGACA
+
*+E?-H>8@>G5GC4D7C9@D;@;<0+>-/8%:,AC6:#ED8+>."?C$:;;1B/!@#@G:*&'"HEHEDA99:+.H/#&3GC:%17?315B1GDG<?+!((5;>+-*9A58"@2(*!3&B5#3G5D03,/)"0C;6/6HD.(<;H>6:F6"A2B29)@C)&C."8@/#A329GD+4'@"G&:
@r9083
TTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCGCTGTTTTTGCGTCTGCCGCGGCAGAGGCGCTCCGTTCCGCTGCTGTTTCAGATGACCTGGCATTCGTCTCGGACGTTTTTGCCGCCCTGGCAGAATTTTCTGCCGCCGTTGCCGAGGAAGCTGCA
+
744+F''76G30<+"&#6$5"B<&+!AA'DF%,C'25@8,#@G7"C*+;9"-&H!+:A*0+(8?-85@@)"$)#>,%EF,:<&#'&'C7*8,""#:1G'37>3$<78&11D92F,/=?A+/9$&:/')"2D!:..C4$%%,B=87'*/9=2;/;%'B#?>CG85CG5HG>BE8*/856:BD@"0%/2;5@+%F;;!E032#(0?
@r9084
CACCGTGCCACTCTGTTCGCCGTCAAAGTGCGGCCCGTTATCCACGATGGNCTCTTTTTCCGGCACATGCTGCACGGCGGTGATGGCATACGTGCCGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCTGCGTCGGCAGCTTCAGCTCCCATACGCTGTA
+
D15<=$"14?$-9--GC55@"02-+@'@1;4&<#8!278B0+046*.+6(-21C;EG&!:3446#+!5(!8F-3<$G37=E:(>"%:0<"FF<-3<:='F"'A$4E><5.,))$A(E&0>&CA620):=.=:$@.&7E%4-&A$.153$,.G/G?59C6E/D5%D&7"2?+*C/
@r9085
ACTCAANNTGAGATCAANCAAAAGCATTCACTAACCCCCTTTCCTGTTTTCCTAATCAGCCCGGCATNTCGCGGGCGATATTCTCACAGCTATNTCAGGAGTTCAGCCATGAACGC
+
$&&""*!!"(+**$!(!"&$#+)*$"&"((&(")'++%$"&)!*$&)*)%%!'&)*%#"$+%%()#++$%%*))(%)*&*$+&+!%(%%%+()#$$'!)&+(+&$("$*#&+*'&&
@r9086
CTGAACACACCAGNGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTANCCATTACCAGCCGCAGGGCAACAGTGACCCGGCTCATACCGCAACCGCGCCCGGCGGATTGAGTGCGAAAGC
+
.H82,37C!?!C4'2B<656,($::E.=B(C.@E$3GH#>)&?<1)0'3)-(:*3*),"D:22#()8;=!8!B?:A6-4G?-6?*6<;/%:*3$%$H:3>C$>-#)(5&9',:<0(#!+!>#
@r9087
CCATAGGTGTGGTTTAATTTGATTTTCAGGGCTGGAANGTGTAAGAGCGGGGTTATTTATGCTGTTGTTTTTTTGTTACTCGGGAAGGGCTTTACCTCTTCCGCATAAACGCTTCCATCAGCGTTT
+
F52<(%C5)$&7.>+,!G=0&4/=8HC@:)D4G2>..>'920&03:*:?-9E17#0:E#F?.B972<%A9?GE:4>;H.'"!8EE7#*5#<9,<AG61D'>*>BDC4(*D/+4<29B>#'5,(@(E
@r9088
GTAACGTCACCACGCGGCGAACGATGGCCTCTTCCAGCCAGCACAGAAACATCTGGCTCGCCTGACGGGATGCGACGAATT
+
4HE0+1$;*5$:AA07?""#<6;CB37G:@%($'<5=9B"18(.$,+(3-D9)=2#0E?CH/.%(8)'<9E:)0=35)FFD
@r9089
AAAGGCGTCGGCTAGTCAAGGATGCCAGCAAACGCAGCATATCGCGCT
+
+))))()#)%'*("*)$(%%)!(*%***"*)%$)%()"*"%#$$#('*
@r9090
ACAGTTCAGGGATTAATGAAAGATGGCAGACATCATTGATTCAGCA
+
)+$A,9+#50=!3$$$CA(,*5=G*!B@=@@@;'7@8@D7'5"E6=
@r9091
TTCGTGCTCATCTTTCCTTCCCGTTCTTCCCTGGTAGCAAACCG
+
@FC08*:;6:A3<'/2E&#*>0.&<F3H!5G0@FC0F$:*6A,*
@r9092
TTCAAATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATNAATTCATATAAAAAACATACAGATAACGATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATA
+
@B)4G-@=&:14&)82%$=B*1DEB?*2%=0=#/='=<4.FA/?(3)("0E$2+;8H"6-G8!7>*A<B20/"4C%0-B>C0"F%=?*8/;EB0'F2./.!:$C%A@;#:H.A,0"BDF<<A12.+?(/
@r9093
CGGTTTTTCCCAGCCACACGCTGCATGACATGNCACCGGCCATTTTTCAGNTGCTGAATAAACGCGCCGGGAATACGACGGTAACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGNCCCTTTTTACGACGCCTG
+
D>83&34H(;<A>B<A9*:'3D%&6%'&*6!=FEGE=<9=!>FC=*#.*8.<<+;(H7D;&*:3B?,HF,C;B41B,0=+?B.#DA:=?<DC;3*$+<,F%2$:G),6:GB3=11;0C,D4";B0BC<2*"3@)%#*;+)6B>+>/:
@r9094
GCCACACGTCCTCCTTTTCCTGCGGTAGTGGTAACACCCCTGTTGGTGTTCTTTCACA
+
A3A4<&;>48=1.:>7AD;E=73%)965$H7C1#0$C;E3AC=F=BEC:;G3/$',(F
@r9095
TNNTTAGNANNTAACCTCTGGAGAGAACCATGTATATGATCGTTATCTGG
+
)!$)$'(!#!!$#"+!)*("&#"'$)($*#+"!"#!$")$(*&!"'"#%#
@r9096
CGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGG
+
H5!>#'B4B-"??7.@+/@)D@A#B%8@0%C>1)7&=>.E?/5)
@r9097
TCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACT
+
C7?+'>/&1F=%3%$A'@0?5:GB3<:).4#2(H1'H'1(#($1D-):;.4
@r9098
TTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGT
+
7#:@A8/449.=1HBD-%?*)B:-'#G?!D3%,BA0)12B.E3%A/&F@GA(#4
@r9099
CAGACAACGGATAACGGTAAGCAGAACACCTATTTCTCCTCACTGGATAACATGGTTGCCCAGGGCAATGTTCTGCCTGTTCTGTACGGGGAAATACGTGTGGGGTCACGCG
+
4,2H":)A'HF!D'25('?&2C>'G<%@)H43C<B:-7)6>D+A?6"::($:-.H&7'(C(B$)?)9<,*2C#C()%+6?4."CF$85+3*29*?B+,#.AA#+4C-&'5<%
@r9100
CTCAACCCGATGTTTGAGTACGGTCATCATCTGACACTACAGACTCTGGCATCGCTGTGAAGACGACGCGAAATTCAGCATTTTCACAAGCGTTATCTTNTACAAAACCGATCT
+
,7G.A61E'6A-4@::EE6&-C$?"!G)AA)E&8C;G=1.+!A0"74*"%"78#E572G;:98#B-*6A"/G/E<>A/.77A6(<B!+GGH<:5?-78A=()*5;%%!*(4,>4
@r9101
TCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCGGGGATACCGGTGTGAGTCATCTGAAAGGGATTAACGTGAAGTACCGTTATGAG
+
$%=2EG7>+=3)5?39?=?:.(=(%G/*%6A4%2,1<0/-#-H.6-?D79=1D*B898<9:&<08)1EB9&E(F((4D*2&69/E32%6)5
@r9102
GNGGANNTCNCNATGGTGGTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGNTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTG
+
"#'##&!%*!#!)%(%'((**+''$$*&$*)#)&&#%"%#%"'""##('!*"'###)!(+"*%"(!!#"$)!#"'(%$"%""$%!!)*&)*('#()*#"'$(+'!&+#!"(#"""')#(#$(+)!(
@r9103
GCCTGCACGGCGCTCCATCGTTTCACGGACCTGCTGGGCAAAAATTTCCTGATAGTCGTCACCGCGNTTTGCGCACTCTTTCTCGTAGGNACTCCGTCCGGCTTCTATCAG
+
#+(#!+#&'#'""&()"*')*&!)'$$&'*!"'*("*''%&+!'$)#'#"(+%)&))*$(*%"+!'&&#)%(*%'$+&(+"%'!($#)('&&)*)*%'$)%&$%()&#%*%
@r9104
ACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTCGCCGTCGCCGCAGTAAATTGCGGCGTGATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGAC
+
=/7$'$F+DB-;D)79!2.G+1DA@697GF:9C=,5#E9@4-)='/.1!2A%*&6)93:B5B<4GB'):1B*</.6'@:=&!+,$88@@+3>=<-5**1(=2(EA*&8=<%FG;/B9&9;/7>9&B!G<0;
@r9105
GCCGTGCAGCATGTGCCGGAAAAAGNGGCCATCGTNGATAACGGGCCGNACTTTGACGGCGAACAGAGTGGCACGGTGAATGGTGTCACGCCGCCAGCGGTGCNGCACCTGACCGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTNAAGGGCGTGAGTTTCCTGCTCCGTCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCANGCAACTGGCGC
+
*4G;B!$0&;&(4'03>,F=9G)GD!GE85%>%@"#(1:9F7=EA4#/$*F<(5&2F4=%E1-EE'?"<A<+("##6<5E4=54%:1603<@3<-@!'0*>AA87<FGC?1%*8D'"D+.894($(=F*C@%/*99%A%=3FGF-A<D791<#;:5A3/61?.7<?=670)9F""*/#)+>9"!6@5B.&2G6+'*$;2G@*<.E#6%B"5A."H!8'GBE?&/-#;$,"&-+<54)2&D5):<5':B87;!%84G3&+3G'$?E:D?&0!?!GB%%.4&DGE!&<&,G43.
@r9106
ACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGC
+
AF0"&#;@9-6%1C=7#*/8&7$;@7DF):-25-;@*&E>.0;2%0DF($?AH02((8,9';%+AHB18-E"5B5,"=$C*-9%)";AG%=>C/;'F*DC"99D'"+#2256%#*.);8#>>C6GA:%1>D@E->@$/'%0/@97;5H%-B260$?7*!9A&(@<>-"?+6H2;
@r9107
CNGTATCAGTCATTTCTCGCACATTGCAGAATGGGGATTTGTCTTCATTAGACTTATAAACCTTCATGGAATATTTGTATGCCGACTCTATATCTATACCTTCATCTACATAAACACCTTCGTGCTGTCTGCATGGAGACAAGACACCGGATCTGCACAACATTGATA
+
&!6GCB*-.'2=CC$8H./3;2%CH>7B7>,G(6(:!D?F>1-;E'B#)3ED*"*,@3,&,*('C0E+6<$@!%>/@7FGE(!6=04H8@@B*)96<9A#.2@.!97)38!5>F%(1C06DCA-702.-35!!71",7DG+;==0198),:@-4<56+F;%-(!<H-=
@r9108
CGGATTATNGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGGTACAGGCCGTGCGGTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGAGTGCGGAAGATGCAAAGGCGTCGGCTATTCAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACGATGCTAGGGATCCCAAACCTTACCCAACCCACCTGTTCG
+
H7"G<(6D&%:4D06/?69,3;7@@H@72,2;FB1':G".@+D/7C=>-'/8B&AF/6(=B-1="-FG!3&)9.H688)H6BD.G+&219;E!B'=F7#,G"(')5#E'4-=6=7==#""7'9DG44=':A;B9':*F?>A=:((=-!7&!$D0?$-*>/)C%65'G8+&&8!+?<6?3,5H%"-E85AE86(>E.@#%?+!(EE>;/E<FA.?%9D9/)1
@r9109
AATTCCTAGGCAGGTCATNCGCAACAGTGGCATGCACCGAGAAGGA
+
),/D&3$H47B;>,E9H>5E#E68=:3%0+H)-D*;';.&,9G:+?
@r9110
NAAAGGATAGTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACA
+
#==78D&FF(C8E.@*+A@&C$?(>&E>-&&=B+F(%23@/64*+73B)";&69;H'D,6AA5-9+@13'6/54F0>@#A5=0;3;0/4&G@@21@+"/
@r9111
TTATCTCCTCAGCCAGCCGCTGTGCTTTCAGTGGATTTCG
+
(725>)+>>@).36:+D2/8/CG&?+?.6A9+5)B@37(>
@r9112
TCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGNCTGCAACAGGCTGCCAGCGATCCGATGGTGNNCGGCATTCTGCCCGATATGGANACGCCCGGCGGGATNGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACANAAAACCGGTA
+
?4B%96FC6&(5A4;B@GG':D.;<$A;A<52:GC,)D'G;9=A5$%;=!6)5A01$+;8+.339C>6+5",-33+-,:*<&-*."@38'%HA,+H:61!F5>2@+3<D(/%6://B$$3/3/=(*52?75?&(&<A-AH?"H&71.919+$+B,CH!HA0A=E4?&6.12-!50?+"H5G*F)>C('"EE.7!29.=!,1@(+'AE@+2+A-=H3B,;ED&>"6.="99(#A/&$4*0.E
@r9113
AGGAAACACTGAATGAATGCACCCGTGCGGAGCATTCGGCCAGCGTGGTGCTCTG
+
*94>(H1=4$5,=)C=4##8*F84;>A.-><A7%;B26E*5H;;)<8.$(1@:G2
@r9114
GANNGGTATATGCAAATTTCGTTTCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCNCGGCG
+
!$!#*$+%!%"#)"&+(#'"%*'**$"*%!"+(&((!*!$"+*+'"((%*)&")!!!"$*!$(+)(!'
@r9115
NAATAGCGAAAACCCGCGAGGTCGCCGCCCAGCGACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCAGATCA
+
((=,:=0E+"7=2G'B!!,$4&);-E@2:$57H8*E$6F%C,532;=8%>>9&8.??C3@6;;?(-/3""H,'=%:?1;*A.:>+H
@r9116
NNGCTTTGATATACGCCGAGATCTTTAGCTGTCTTGGTTTGCCCAAAGCGCATTGCATAATCTTTCAGGGTTATGCGTTGTTCCATACAACCTCCTTAGTACATGCAACCATTATCACCGCCAGAGGTA
+
""<"1+>>-67-;C=)6#A0%15"0*@>?3.-422E<,#,EB.E8*;;<.<CE<3$;G=??'-A!*"49&D92,BE<,@G:68.<==*'2H:93(26+B<G>.7,6.C0/:B838<*(&%88$=4:H<4
@r9117
AAATAATTCAGGGTCAAAATATGTATCAATGCAGCATTTGAGCAAGTGCGATAAATCTTTAAGTCTTCTTTCCCATGGTTTTTTAGTCATAAAACTCNCCA
+
5>.G$:;0&A%@?C:<54H+-#?4*>-))!(G'>F;8.!4>"B*8F<7/5HG3<(.G,.91G'(*#9<4+7'34H-?'?/BHDD-8&B9!:78AG#?&.)4
@r9118
TGNGGCTAACGTATGAAATTCTTCGTCTGTTTCTACTGGTATTGGCACAAACCTGATTCCAATTTGAGCAAGGCTATG
+
&'!((+)&)%#)&'!**)%*+'"+)'*#(#&*!&+%)+(!+("&""''#%)$!"**%"($++!++$!#$)(!"+!$"$
@r9119
AGCAACCCCTACAGCCATCTTCCGGATGACGTCCGGGAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCGCAGAAGGTGTCGGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTCCAGTGTACAGCGGTCAGGAGGCCATTGNTGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGCCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTG
+
!/=!%3;($-"39;(>26E=*)<7<;)D/@F(:#4-.2F18+8)/C=38G>5E=.7CCF#$'5#H=D+76388:#+:C%1E4>#E81GFF>!E>/0C:8.!%',<23#D6E:AC%@EF**&D210(D%>H*.@DDD>;BC113&:B4(&D@<$%<5H)9G*'A-64B(A7-#".H*:#H-'G0)C>@@53;"@H4/-%!!;67$,!H71/$B#0EH@B%%$DB6B:09*'*7?06'3()9!C;02GF3#((2'>C@*6)/)'-:>!F==6E3@*D)'/F.E<7=+A?5-C6$2=@#1481-5@8
@r9120
GCGCGCCAAGTTGCTGCGATTCTCACCAATAAAAAACGCCCGGCGGCAACCGAGCGTTCTGAACAAATCCAGATGGAGTTCTGAGGTCATT
+
$?>HB)/A6%&1=%4:89H%0=9/.=0;%+!;,.<#!9;$=$33/F<$3D#"4B"+1?7==-3@2+/,F<#&-/.=+;#GF9CC;$!4"E3
@r9121
GCAGTGGAGAGCGCGTTCAGATAGAGCCACTGATGAGGGGAACC
+
G'A!2:*-''A5!*4:H)395/(AAD(:>DB3:2#&?:B9/F1%
@r9122
TNCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGCCCAAAGAG
+
$&+(&''(%+!!)&&+%*$$&+%**%%')!"!+%+%!&*%)&#'#&%)&#*(
@r9123
TAAGCAGGCCCATAGCTTCCTGTTTTGGTCTAAGCTGCGGTTGCGTTCCT
+
8*62"6AE0B%*3/-,",HD#E!(<D#+=!7D3*E>+<$9C2:?5!'278
@r9124
GGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGNTGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGT
+
=(C38#4,;.&G5;E%CE)-A7$B6F-/=?&21;8A@*??:H6D4A<H%'AC-&.0"-HF@&D0E#)6B">21'%$4%$G$CA3G%29./DCA)C=.<5B(8&C321B)H./B#A%!&&<@"4A!3+':)+&',E<6-1(8E+E",4CG1;.4<3<@(5B=<$)1@$?66++*;?)</#:9H/+;7A9892>?B@12/
@r9125
NAAGCTNTTTCCGCTTTTTCGCGTTCTTTACTTCGTCGTTCGAGTGCTATC
+
#%!$((!%+))+&#)(*)&*$!'%%")%'*!)(!"&"+)$$*($!+)$$"*
@r9126
TTTAGCTTTCTGCTTCCTTTTGGATAACCCACTGTTATTCATGTTGCATGGTGCA
+
69D(B'$%<./;D8%%%"*/+3C<*553%8<../3H/$+*8!'?5%&>D<G;7//
@r9127
AAACCAGAGAATGCCATCACGGGTCCAGATCCCGGTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGANGACGCNGGCATTATGCTCGCAGAGATAAAACACGCTGGAGGGGTCATCCGGCGT
+
>9+::"-1/AE'(->C@AC'*&..=2!>0:4=9'>62D5?C6&$*#52%1F&>DH?;48'(@42*$"0D+C>E%G3-(#7#'3#&/!A#1@;>3<4>@36=(-:1C%;$'5G?!4/$/(7:F.5>8F9G<9>,-5D">!H2
@r9128
CATAGCGTCCTCACATTTCATAGGTAATGACATAAGTCAGATCGGCTGAACTCNACAAGCCCGCATCATCGTCGCGCCGGTAGTCATAGNCGCTGGCCACCATACTGGTGATCAAATCTGACAGTGCCGGGATATCGCTCATCACCGGATAAATCCGGGACTCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCG
+
(,E*CF=%G:,#,#9<CB/A-B,/'BD&"G5E5<G">-%&GE=#H+A'=>C:"*H1)>:="@F?,5.$D9.'.=%A@*4:4*D,CE1&9!B::'3)C8H1F:C/)F15<1C5G-&$-8*?*D@.7?1-D;&6+9#/!0E1H./2*.F7/F:9%A1:;-*"%#*#@%=6F5/3E>1""4$&%$;-%/<0)45@HA7'=&AH7$-"/&*1H!A9$C&
@r9129
CTGAAGAGNTGGCATATTGCTACGCAAGAATGAAAAGTGAT
+
+!&1&5;3A'8&$%D'8$:GG5A5E)C.C,()E@.H1/7B0
@r9130
AATGTTAAATTCTCAAGAAACACGCATCTTATAGAAACGTCCTATGATAGGTTGAAATCAAG
+
'CD9%%<+CH8!+/1+$H+5"9,AF46=15:F&G:/-'478=0=DD'0E@D?+D-1H-@(B$
@r9131
CCCGGATTTATCCGGTGATGAGCGATATCCCGGCACTGTCAGATTTGATCACCAGTATGGTNGCCATCGGCTATGACTACCGGCGCGACGATGATGCGGNCNAGTGGAGTTCAGCCGATCTGACTTATGTCATTNCCTATGAA
+
(+)6234388*4:''&:H5/:F<(/-C6C!'%,:4AG,7+;%'?G9)4@"!13(9":+3A7,?!</--06)289%:>+&G&)3?:"%>(-=F6>=3EFD1!!%*@:.@09FE0F!%4&=6=A(+<H#$$$'/61A!A!E8C8%
@r9132
GATAACCGTCCTTNAAANAAGTCGTTTCTGCAAGCTTGGCTGTATAGTCAACTAACTCTTCTGTCGAAGTGATATTTTTAGGCTTATCTACCAGTTTTAGACGCTCTTTAATATCTTCAGGAATTATTTT
+
@(H95G?/@E-5G-9DF2D*,%#$A5?)F%?%:(80D,*.,65H751C96<2(!G347*!8"$,8(A9"7D$"8@0=D-$$%@/12D./?F'=4<-C!%,*D*!5!'GAB01;<1!/<"AF=$+(C,7B(
@r9133
GCTCACCTGTGGGATATCCGGTGGCTAAGACGTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGCGAGCTTTAACGTGCGCTAACTGCGGTCAGAAGCTGCATGTGCTGGAAGTTCACGTGT
+
1+A@1C#H%3)+/BB*2$-(8*F'8,BC*=@E7FE73?0F?F<H=?<8+#;50F#/,&*4?#30E=%8H//*@H8H3651:$HH"C4<?3+563C%3D4C)/,&+<6!!7@.G,;*>8D9C>$EH11?<'=FH3B3,2H4G>,$80B=E8
@r9134
GATTTTTCGTCTCGTCGCTGGCAGCCTCCGGCCAGAGCACATCCTCAAAAC
+
(!/(@4#A:830;$G,!0#EB)0>BG0%!)(GB#;>$?DBF-+@+,AF&'7
@r9135
ACTGTCCGTGGCGCTCTCTTCCCACTCACTCCAGCCGGACTTCAGGCCT
+
)*+%$%)##&&!$"*("(*+)%"#)+*'&"'(!)*%&$*%+#"#$+%*)
@r9136
GTGTTGAGCCTGAAACAGCAAAATCAAAACTCAACGAGCAGCGTGNGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCGTATTGCTAAACTGGAAAGCAAC
+
93*F;706)EBB50;;59/8C'8(?A19208'D15,1,?<4F/+#"861/'8.>2#5#$($=@%BA*HG57+?3&"@B7A;&4'1,(!G6;+F<E;DG83E<"-
@r9137
ATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGANAAAATA
+
;0#F:2?%-@=!$%?G5*-2?85>>/=.(@-81/CF"#,)$,4B*-*CBG!-6>76("#,5
@r9138
GNNCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGCGGTATCAGGACGACCAATATCCAGCACCGCATCCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGG
+
*%",57/D#"64-2><&3H"!D#''C#3B747:0G/<'=H/.E,:299A"'C7-AF/EF-F8.21D1A&G,,H'%:B;&@>%,E=.H3#G@<>*4/G374.G$;&>F4!+;6=CB:@9E"1+5;<>202B0F'%1%3,H:,@.'0*2E>G:B8E+-17E)#7#%6),!=,<
@r9139
GCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCANTTGGTCACTTCGACGTATCGTCTGGAAATCCAA
+
E>28!)?.+1D-400A=):(21D*,.:A/@HAD#@8&?.@,9/).&&7)9/2BH$&+3A;EH@':FB(548>%!>F?4=F!-&H15
@r9140
AGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTAAAGCAGCAGG
+
!+?.AH</)G9,E**=-D:.<4E#(H,;8*=".F&:B;1B7>38D7A#4%77G6
@r9141
GGGATATTACGTCAGCGAGGACGGGTATCCTGGCTGGATGCCGCAGAAATGGACATGGATACCCCGCGAG
+
'9D-6!;(-!9E6"BG,4!8,DAH,<+!0308!+.@8H)@B68,)DH(F(8'BF/F=@78H?!:B&/+H7
@r9142
TCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATANGATGACAATGTCGCCCCAAGACCATCT
+
:5C!*:,)/%?3#-;6)D4B$B$:H9&'"$88C=:2B0+01/%&8;+B47&H#$@):)#>B;78>8+(2$<3(34%-G:+GC
@r9143
TATGGGCGCAGCTAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAG
+
65&BG809*G/G1D@#71A&@4>-7F?;'4",$D'%905<0%?0;E7AC/73E:G!"
@r9144
CCATTAACCGCGTTGCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGAGACAAAGGTACGCCGGAAACTGGTAAAGGAAAGGGCCAGGCTGAAAAGGGCCACGGTCANAAATCCGCAGGCCAGAATCAAAGTTAACCGGGGGGATTTGCCCGTAATC
+
:%=E)>2C'.7@;+?4>31<7B3E>-8.&7.-?E8''?@861.>4+.6,+*C&%2B==(3$&*,A3B$GE;F?70C0=@'6:.B,0184(/"G6AH0#?<*E5B2FA((-'2/@H)6C%9>8&A(E*4HH"1$D@&=+<?61GF=-7:./$7=$$*2C$=(BD#$:"
@r9145
TATGAACGCTCGAAAAANCATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTAC
+
?2#F%CC+@2*H!;23)H)4/1,H@#3$8526A(,&468D*7&(C#''%>?%#7EC;@*!:3;
@r9146
TGCTGGCGGCAAATGAGCAGCGGACAAATTTANGTTTNATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGA
+
=*0H84=0A$%!)A$7<B3?=GD'0-<FDH&.3E13:&")=>D6@0!9/AH5?$C8"B*8?:#CC-68!6<7AB%>68G6B(1(A!6F94
@r9147
TTNGAAGGAACGGAACAGCGCCCAGCCTTTCGGATCGAACACGATGATATTCACCACACCGCTGGCGTTCAGCGCGTAGGCTTCGATATCGTCGGTCGGGTCATACGTGGACTTGTCACGCTTGCTCCACTCCGTGCCGCCGGACTGCGTGATGTTACTCTCCTCACTGCGGCCCA
+
7$7<A5-+2DA'740(A&50,%G73G3E)%'/?++"?:=%2HGG!HC@A5!#B:34H!FFB+59;'&=#@@3?C0951G6GA3+*:FF"193*;,94AA>;15H-@"<(E/D+?,G%?"34A+0+C@@%A.HD4A<!$)9<*B<(&%2)7E-F?8!5B6H5G8C)30%@3;46<=3
@r9148
TTCACACAAGAGCAGCTTGAGGACGCACGTCGCCTTAAAGCAATTTATGAAAAAAAGAAAAATGAACT
+
),";717A<+>'$(-4/&%!9EA8<$(FB;4',G:,!BC1F!"#8F&-CC66:GC3#*67H0&/5*#A
@r9149
TGGAATAACCGACACGGGCAGACTTCACCACATTCACCTCACGGATGTNGTCGCTGCCCATCGCATTCTT
+
:>%E:?6:C>GF?+$=<.-:;HB6-0C*4/=7!>>F8:*4:%3=,(3#)6*-3'D0EEE2/C/)5)?'/F
@r9150
NGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGGACGTTTGTAATGTCCGCTCCGGCACATAGCAGTCCT
+
+'"%)(%)%!&#(%"&"'"&))$!(')'('*##!$"")**$$#''$##%+"'++"!*"#'!&(!$(+((&""'$((&&""")()$!'(!%%**("+
@r9151
CGATAACTCTGTTGAATGGCTCTCCATTCCATTCTCCTGTGACTCGGAAGTGCATTTATNATCTCCATAAAACAAAACCCGCCGTAGCGAGTTCAGATAAAATAAATCCCCGCGAGTGCGAGGATTGTTATGTAATATTGGGTTTAATCATCTATATGTTTTGTNCAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTGCACGGTATCAGTCATTTCTCGCACATTGCAGAATGGCGATTTATCTTC
+
;!4FA0<F3<,>7+%C"!D/D)%@6-*!&!CB@##!#%H<FB>;'C72=G&*"2A$;G>$.4.$<<%H38/=85?4H#?.B<.$),=%9GC)$%D@@1(463>/+:"0.4*60/.H(H><6C0F'B@5.>2.<&-G(D':D4.(=.1B:!E+EB99'"62@#*E0=.?8!+C.!)B(5"'<22F(B$."(11%/,FD<CD;E6B%57>E3E)"%"@E:8A)E'B7H<:&D0)="+8&&@)C#2!>5)!)8DBD8&/"1G'
@r9152
NNACCNCNAAANGATGNTNGNNANACAANCNNNNNCGANGCCNNNNNCGTNNGCTCCAANCTTNGNCCGNAAGGTATNNANNGACNNCGCAANNGCNNCTNNCGCCNGAACTGNCTNGANNNTGNNCANAGNCNCGGCNCCNGGANNTNTNCGNNNTTTNCNNN
+
"!##"$!#"!$!#$#$"#"$"!#!#$#"""!!#!"$"$##$$!#"$!#"!#!#$$#!$$#""$"#"!##!#!"$$#$"$$!$#$#!#!"#$#$"#$$##$!$#$$"!$###!!!##!#"$!###""!$$!$"$#$$$!#"###$#!"$"$$"#"!"!!#!$""#
@r9153
AGCCCGCCGGAACCGGTGGGCTTTTTTGTGGGGTGAATATGGCAGTAAAGATTTCAGGAGTCCTGAAAGACGGCACAGGAAAACCGGTACAGAACTGCACCATTCAGCTGAAAGCCAGACGTAACAGCACCACGGTGGTGGNGAACACGGTGGGCTCAGAGAATCC
+
./5G6(!5F#,(!$7%/>?.,D2G.&<8;;.@<0/@E!6&2)+.6;7)A79+,GC>:/)(.65B3E:A<0CG7C?@!<!9)(?D8(9$70.F4((*#G+B69?09A;75+>G70'039+F0;"?E%2=@!,BD*C"!(.==$8@%,5?CA5C,<%0?FAGAG.,&6
@r9154
TAAATATCTANCACCGTGCGTGTTGACTATTTTACCTCTGGCGGTGATAATGGTTGCATGTACTAAGGAGGTCGTATGGAACAACGCATAACCCTGAAAGATTATGCAATGNGCTTTGGGCAAACCAAGACAGCNAAAGATCTCGGCGTATATCAAAGCGCGATCAACAAGG
+
HHE;H;5D918>@4C-&<3,2,3@!/6<><$FF!1%7!+,8D;$$"<-:&"2>1C2.?#&%H;EF+@!($#*A8E7($H*F#B#:'E<-%9<83%*G=&"9B4('75F.B4*/@;D/%H)5:9;-C1G5FH'E0AG;:@,*@EFD1!*2%$-)#,7!:0.19B"7D*3"*>8
@r9155
GGTCCATTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGAAGTGGAACGGC
+
6:8'%@$*B=%(*<-)>,%D$0A#F58F&#$3E<A"#*7E,F*2+1,,A)8/EE2:&>632D=
@r9156
AATATACCCGCCTCTTTCAATAACACTAAACTCCAACATAAAGTAACCCTTCATTT
+
9H7,-/CC<?:G/9G>?"C429)$CF&'&>H(HB(8='%$;?41;!&'7,4>9+--
@r9157
NNATNNGNCATGNGAACGTCGNTGACGATGGCGTNCATTTTCCCGTCTTTATCATCAACGTATTTTCT
+
&$#'""$%$()(#($&$*#'"#+%*'"#!(#)'+)#"#"**$+#!+$(!+!&$*$)'$$'%&)+""*"
@r9158
TATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATATCAACCGCACGGCCTGTACCATGGCAATCTCTGCATCTTGC
+
.@7C)%C-6,&"H(=AG48CG/2$+7,6FC1D1&")1"11-4E(C>?7.F*<>:<64E*CB5G9.BA;&9&!=<#/>%&$?6E--$)B9?@*-=+H1/FCC#66.;E:1GBDD901A*.1;34",9$<5G%;7<3!=
@r9159
ATGTTTTGTACAGAGAGGGCAAGTACCGTTTCCACCGTACTCGTGATAATAATTTTNCACGGTATCAGTC
+
1D@CH$#B&321:A#,.?'@E2.04"/:.*+D#8>#BE.?1,5/&5?D%$?"</04?,1&3AH.B%8?H+
@r9160
NGGCGTGNAGTGCAGNTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTNGCGACTGGCGTACTGACGGATTCATCGCTGGGGTCGGTTATAAATTCTG
+
.5H/H<08@"'=;?!EH3BB/?2C5#><5DH4;&G"%#%B9A@+?&>6((6A4("D5##6'9'C-2$H%>5'//%D&HF#21-&G)%,2C?04$'7;)$5&??=<G6+G0B.E6020H13+5?/'!<
@r9161
NCGNNAGCANNTNTTGGTCACNCGNNNCGNNCAACNNGANCNNGTNNNACNTTNNTGGNCGNGANNTNAACTNNANTCTNGANTTNANNNAGTACCCNANTNANNANGACGNNNNTAANTNNNNGNNCCNNNNANTTNNGGNAG
+
"$""#"!##!#$!!!$!$$$""$"#!#$#!#"$#!!#"#$"$##"!!#$"""#!!$""!!!!!$!!"!""!#!#$!$$""!#!##"$#$!""$!#$$"##$$#"#"!!$$!"#$!#""#$#$"!#!!#""#!"##$$"$#"!#$
@r9162
ATATAGGACAGACAAAANATCTAGATCATTTTCTTCCTAT
+
>:+.AF6..B>F'.;-@4%?>:)'"*4)"+97GD#+..9*
@r9163
GTCTGCGGCTCTACCATTTCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAATACATAATGAATGATAATAATAATANTAAAAATTTCCTGTGTAACTAATTTACTATATGGTTTCTGATAAGAATCATTGCAAAGATCAAACAACTTGTATTNCATNGACAGTTAAGCAGTTAATTTTATCACCTNTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTTTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATNTATC
+
5/;!'B9/9/+G@(F/3&F21&.*,&6,9*374FHDB+"G-9958;C(!>7F;.+<#7)&'28+4'4==+C)6E8/7C+$D341!E(.FA>&H.FF>G4&#8<(!6("':@C8#D06/;C(&8#55#*(!3">ADC;!9B,H,9AF0?3A<2;5&>8=-):H7:C;-7@$,):&.>:9A:7EF15)&F+,#9F(FE((C5,<DC">#G3/B=>*%;?:'+?7,2#+B4DE!9"-0&("A&:-#3D90%@E6=#<+-"G9=AG*6*1E%&)#H=??<HB)*9=)!4<D.$H62
@r9164
CTGTACCCCTACAGCGAGAAATCGGATAAACTATTACAACCCCTACAGTTTGATGAGTATATAAATGGATCCACTCGTTA
+
%H:-05H+.?8%9>5,A(A1)@9<0-C81.00-$;9?+-D*9.@G134*(1&C96(.<2,(1@2A=8@:(%G:*)A#1C3
@r9165
NGAGCGCGGTNAGTGCCTCCTTTGTACTGTCCACGCCGACNGAAACGGATGGCGCTGTT
+
%+.G?71(*G6..0-,31#"A=">A=&')&C2=99@A':C746;&)4-<:F373.!291
@r9166
NGCAGGCGGCGAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCC
+
!78C$"%;:!$(?8*$'3/B@#9,E=.,&6.5H3-!G)%E26#9/BGG/%1#8"
@r9167
CAGGTCGATTTCCCAGAGCACCACGCTGGCCGACTGCTCCGCACGGGTGCATTCATTCAGTGTTTCCTGCCGGNTATCCTGCATCAGTTCACC
+
8E"><81G/$=@D):3/.!4$5-89B@/A/872H53*5.<F>A"-,>"F?9"B$:!:CHC(.5H/D>+HG=.:C>#/*57?:F;?@):0D.=;
@r9168
GCTTCATCCGCGATATCGCAGTCGGCGTCACAGGTTGCCCGTGA
+
$<H?&=7?76#/(>67>!6H!%/C8+3D%.@3;F8:*3F!$.<:
@r9169
TGGCCAGTCGGCGTGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATG
+
@$"24;7%+%5803,'@4A''9@/6$+1>57"1%'0&/5=9>@E)')"&#-/;$.B@!%:1.:<(
@r9170
AGAAGATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGAACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTANGACGTCATTGTAGGCGGAGAGCTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAATCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGTCGTTG
+
-0!?!D7EB8C,&*H;:H2*B79E.ECD:4,B..-4&7F#'1F6)*72?6<-*&#D11%E,3-E4&-/:955?=<=;:+%37B8:2#6C%7E;:;>H1F#+A;-1<0C>"#"="$@)1D<8?CCC,*2!G1HGE(/*F-20@#87*6'&C&E/6A#H''E=H'B8A6/,><=#/?9'1.?H3G9:"/*@A&B&$%(A7&1<:;D1%/7@9-&%.05=(#5=2>E<6>D+
@r9171
GGCTGACGTACACCGTGCTCAGCCTGTGTTTCAGCGATCCGGATATGCATCCGCTGGATTTCAGTCTGCTGAACCGGCGCGAGGNTGACGAAGAGNCTGAAGATGATGTGCTGATGCAGAAAGCGGCAGGGCTTGCCGGAGGTGTCCGCTTTGGCCCGGACGGGAATGAAGTTATCCCCGCTTC
+
3D.0@)$G>)4=&?((-;1A:'2&AA*HF68@-"D5*E5H#:'!E*;B?2%&;87D<:&>1-*H?&!$G<8AGE%.8#+3*3-H+3@(5(*2+&(<F/F214!;@H,E-1%57-<&:H5<0%G;#)B!*49(:C7%++9-81.6-B8)!(D*"<D%A?A<<;#987'G85-1=?3*+B"!1:%D
@r9172
ANCGNCNTGTGCGCGGCGNNNCCAGCGGCNGTTATTGCAGTANNNCGNTCAACATGGCAGACAGCCGGTCGCAGGCGTCAGGGACGTTTGAGCAGAATAACCATGTGGTGATTAACAACGACGGCACGAACGGGCAGATAGGTCCGGNTGCTCTGAAGGCGGTG
+
*$(*!#'$&$*)%'&&(""""&##%**'*#&*&"'!!)#*'*#!#)&""&)$++!!&%+#%("'++'+$'&$+'**))(#+&%#!"$**'!'('*'")+&+'!!+('"(#)+!&*"!'**&%+*&%$%!%&*+#%$%#*)%""#++"+&*#&$(#*'"##+!!*
@r9173
TAGTTGGAAAACAAGGATGCATATATGAATGAACGATGCAGAGGCAA
+
G??3%"$5:D/A/0(@987D-A$71:2:;;6D15,1":@G))?)0.+
@r9174
AGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCA
+
3%"6"65&A!''(1G&-0BG"89+*9:$57%)G/'H#-A"G#!D.98);;-%
@r9175
CTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGG
+
@32#%HE#1*+F?+$G+%:2)CF/3D*&E<2BBA8?F8/G+%AA7BF!"&?5C=!2'168/3..&
@r9176
TAAGCAGCACGCTTTTTAAGCCATCCACCGGACCTTCAATCGGCC
+
$'/81.!:37G>'9-!77'7>*DB2E&HFHDE6F7,HH"C(E67A
@r9177
AAGCTGCACGACCGGCACTTGATGATGCGTTCGTTTCTGATGATTTTGCCGCCTCTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCG
+
83D3?7-"(6.#>$()0,F&C=C?@7CD>:>0+<535-!8G4?*0C(!AA/3,.1)H%HA!01C@6:E,0D)39'C(<=D=)24:9C:&
@r9178
GCGCCGCCACAAATTTTGGCTGCATCGACAGTTTTCTTCTGCCCAATTCCAGAAACGAAGAAATGATGTCAGGGTGA
+
>200"&B1)@>B61<&$/8,C052E.3;F&GF0H=E%:-64;<=H#$@F,A&7(F7G00>"!"A98-!$+D'<941!
@r9179
AATCTTCCAGTGTTTTCTTGTTGGTTGCTGCACCATCCTC
+
<-3G%/'%%G!&-.*5F?677@A275D<2:G#0(A!/%@=
@r9180
NGTTTCTGATAAGAATCATTGNAAAGATCAAACAACTTGTATTACATTGACAGTTAAGCAGTTANTTTTATCACCTCTAAAATATATCAGCATCTAGCATGCAACCTATCAAAATGGAGAGTNTTATGACTAAAAAACCATGGGAAAGAAGACTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCCTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGA
+
'?:-7,$A<89<66</#3=-#'1DGG##F.3=E<)270%7@59B-;G005G$!&8)0,3!2(@:2.$%*666A%6?0G2E=0F@.4F@%<.E$F%G7&%H66*9H.6<"F:?7!F*-G!6-F1/17<"7#&+5#<8:9BE&E&7&>B3+2(82B'@./-'*E%48&92+=D4(DA=A5683*%%@2=5<(7H*;8=F;B"(95?G+D3:)G1;62;95E?A=*2(@E@9B<##;5F4G+B+(,4//@1=3)
@r9181
NAAATGGCCGNAGGCATGTCATGCAGCGTGTGGCTGNGAAAAACCGTTACCCCATTG
+
!(&%$($*&("#&+#'($+)"%%#"''+"+)+!+&#(*'$'$+%%&"&'""++"%#(
@r9182
TTCATTGTCCTGCTCAAAGTCCATGCCATCAAACTGCTGGTTTTCATTGATGATGCGGGACCAGCCATCAACGCCC
+
5;@F45(!8::61:0>+21=7$4%366.5%D(-3HH&4!B%;203'(=/#FE4#>A0;6<%H14D?0@:87&H'-@
@r9183
CCNCNCTTTCNTGAGGTGCGCAATTTGTCTNCNAGACTNTATGAGAAGCAGATAAGCGATAAGTTTGCTCAACATCTTCTCGGTCATAAGTCGGACACCATGGCATCACAGTATCGTGATNACAGAGGCAGGGAGTGGGACAAAATNGAAANCAAATAATGATTTTATTTTGACTGATAGTGACCTGTTCGTTGCAACAAATTGATACGCAATGCTTTTTTATAATGC
+
$#!$"(#$)&""!&%&#%'"'(#$)%()%*)%(*&'$&!'(+%)!+!"*)'()"%')("#&!"'&&#&)(*%&#"&"'+)"#"'$)#*$$""&(!*))'%"'$%"")(*'+)%+#$$"'%%)%%!$*'&"+)&&)((!%(*$#&$'+&$(*&(!!*++$+('+')+%%"&"%%&'**+)%%#'%)+$%*+*!*&!%+$!+!(*''*$))!&(#$'%'++%&*#!&%&)
@r9184
TTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGT
+
=E48"7;828G<5D&#:(3>.9-25B5#G=D6=,!'G)CE=2"1C*<9D@CBF@6,,*@.5CF5H
@r9185
AATGGAATGGAGAGCCATTCAACAGAGTTATCGAAGCGGAGAACATCAACGACTGCTACGACCACTGGATGATATGGGCGCAGATAGCACATGCAGACGTAACCAATATTCGAATTGAAGAACTGAAAGAAC
+
FF$&E$,.06=@%;%3,G($-101<0F?%1E+4)%:G?)G>C)?=54:!E/G>:#>%7D?5A-?-B!8"!.@0#59:=AC;E&'0=G?BD:>>D&/2;'("!,A$B5#+2:%537F<!5>-=6+%G*$+4;<
@r9186
ATCAGCGTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTC
+
;?69F<3C=E&HBH0(%<)<7D+,3F2,B:8G&,6@-=)!#B
@r9187
NCCNTTCAGTNCAAAACCGCTCCCCTGAATGGGATACGGCTGATACTGTCGCCCCTGCCAGGTGACCGGCTCNCCTTTTT
+
(%)*"(%&%)$+*"*&#!($$!&&$"")$(+%#+*#)(!&&#""!#(*'$'&$&&*!&$$%'+$(+!+)+$+(&%+$&&'
@r9188
GTGTTGTAATCCGCCTGCAGGATTTTCCCGTCTTTCAGTGCCTTGTTCAGTTCTTCCTGACGGGCGGTATATCTCTCCAGCGGCGTCTGCAGCCGTTCGTAAGCCTTCTNCGCCTCTTCGGTATATTTCAGCCGTGACGCTTCGGTATCGCTCTGCTGCTGCGCATTTTTGTCCTGTTGA
+
-"<0@!668@@=G9&/6.0195;'CA'7C$*A&B,@$A<>58GC-5*.=A#4!"9C1;/:HBA@H0&39<0BA0(<%%08',D=(!(?C7$.8.@%BH%6D6A9.A,-=$<;25)7:4'*&/3AG*#;4<G6'C5E/3?5(75'G&?#'2+-"@##'/#.=@2G=+4CCA=>%($/A68?
@r9189
ATTACTCAAAGAAACTCTTNCGTAANAGTTATAAGGAAATATAGTTCAACCGCAACGTTTCAGCAGATACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCTAAT
+
B=G$!=.$AA7$AFG(+ED<=4@%EC>7C?&)F?(7)6'-&?<E"6='9.54(DE2.3@<28>C=D,(!F2*#8A;2!*,8F59FBF?'%&D9;+*-B+D(BHB96D,154)(F.0B>C5<(6$G:G'0
@r9190
ACAGGCCAACATTGAGTTATTTTCAGGACACAAACACAAGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGC
+
/2%:/2B<1)$:(/6+/3A(!!8.CD/(#.+H$*69=3*;<3147;=)24%(@C?1?;>EA'9D0+'G/"=&*F@.!+3<'*:3!31#2D?6:.@4;/!0
@r9191
AACATCTTTTCATCGCCAATAAAAGTGGCGATAGTGAATTTAGTCTGGATAGCCATAAGTGTTT
+
+7+"6&3("D:3#3/94?D70HB=93?:/3).A+3;#%H0/:@"$.D4"F6#$"$B2C-A#AGG
@r9192
NAGACGACGGCAGTGNGCGGCTGGTCAGCACGGCCCGGACGACGGAAACCACATACCGCTTCACGCAACTGGCGCTGGGGAACTACAGGCTG
+
!!*&+**+)%+)%*%+$$&(*#*$(#$))"*%*((&('%!%'&"*!"*+&"+$%#&$)&#+'+!!$'$$"'&&*("(""+%+%!))*$!#!$
@r9193
GGCCCCGTGGCGTTGCAAATGATCGATGCATAGCGATTCAAACATGTGCTGGGGCAGGCCTTTTTCCA
+
EG3/-*44F/,94H)%4$,!'8424;G"84-F)7("7!"F!1G)$#=7B3)?F6+%D%E.2"B)1AC)
@r9194
ACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCGTGCTGNGTCAGTTGCATCAGTCACAAGGGCCGGC
+
;'@"<!!7GE96@(%=0/38,1?/(?+:(?G9""$4!!($C>.G6>"?->=+8,0.=-AE3%0+0)CC.F!
@r9195
TAGCATCGTCACAGCGCGANATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCCTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATGTCAACCGCACGGCCTGTACCATGG
+
5A"$?0E'-B?:@#9+G<H#E?3,3'6/;"AH0#G&080!?4CD(2821.,>8<$,;CB7($*0#"&2;=@.G1&<!(<9;.7@H!&!4#F*A!"<!9""76C5#.0?<'=,E'2/4*--'4>4H0A(+%AAHF1%#)F
@r9196
ATCGAGCTATTCGGATCGCTCATCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAAAGCTCGCTCGACGCTTTCTTGTTCGTAACTTCGATTTTGGTCAATCACCTTGTTTTCCTCGCACGACGTCTTAGCCACCGGATATCCCACAGGTGAGCCGTGT
+
H?3(7DEH=)=<'7499B+8<6785C<:<0")+4+FF(.5B0(!-4?"+CB6G!08G>6#;"C-B+"((98-%-)A:;E66F8+<E!G>%>!&>95#+/EGCG#<+'(G&61.2GBG55@6A!*(,G*/$1%4F!#F#?'2>>B$'F&@G-0;<5:9;++=-DC(<$6A4,B:/7-.?&E8*;B.11!8$00"B?E<)77>
@r9197
TCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATAAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCAT
+
=/<FEH1+9.(G<4E&?0#A3.$*09C)<#.)"!>)3-!G1#%4"2>"*8.<;;;;34',)#)>#CA.)2"A5,%C'"<0#>>%6"'H>$*5%D*A
@r9198
TAGTTGGCNATTATTATCTTCAGGAGAANAATGGAAGTTCTATGACNCAATTGTTNATAGTGTTTACATCACCGCCAATTGCTTTTAAGACTGAACGCATGAAATATAGTTTTTCGTCATGTTT
+
:'=8>*7+H'88-C*F)2!.8GE32)&7)?!61+4*G=H(*#;&%70C4&>!A@3#%.H26?4G8=..>+H3G7!C<6@/,(A&)<"GE(G/.:/52>,F02>+9"/.!6=8A.:D(EHB2,F@
@r9199
GCCAGNATTGTCAGATTTCCACTTTTCATTTAATAGAAAAAG
+
,%F?97DE="93&<=74@(H#!3B4H0+5>+!<D8996>F10
@r9200
GTAGGCGATCTGGTCGTTGATTTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAAGTGAT
+
8D@7'=?85;G<5'(B<3:H0&C5/F68HA6,5'569F!$1!5/)4+=>3@G@0BA&B?F@71D13FA-/1HA*)&%@F5.?D/3*7;*(0@6>59
@r9201
TGTCTCCTGGGCAGTCAGGCTGTCGGCGGACACCGCATCCGTCAGGCTGCTGATCCCAAGCTGGCCT
+
*'*&++'%'+('!)%'&)'&!&##)$*!"'!)+%)+%"$#)#(*#&*+!+!"#*&()%%*($)$('+
@r9202
GGGGCCGGTGAGAATTCGGCCTTTCCGGNAGGTGCGCCGATCCCGTGGC
+
G,4$,-4%C$?"CEBG/6@07!')B&7!4$H+%*6@#2'.+))H"G@FA
@r9203
CTTTTGAGGCCAGCGCATCTCGTGCTGAAGTGGCGGCCTCTGACGCTTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCT
+
&8$BA6#/E)9=.3EA3&>!0)A/9#,;<2+E#)'.7<-DF19%9$69C#5E/FH@E;1=&?)22*!6%3!3?7"8/:$EB!>03B+09E9)8166C)!53,'@/4@!*GB9,BB2&2:C8?G!#G=G)$<&$;E8>9*3G.8(@3#7@(%+8=A#BGBD6
@r9204
AGCCGCATCGGGCAGGAAGCAGTANACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCATTAAAAACCATTCCAGACATGCTCGTT
+
(+)!(")!$+&%'$)#)'''(#)($'$"'+$%++'"%+++()"#*%&*!"(*$($"#"%*&'%"!)!'#$'!(""'%#())#%+++%+%+(%%+++$'!)+"("(&$'$(("&"*)&!")!*&#$"!#'*"$#%$&&#$+)!('&'+#*&'%#')&!'#("+))+!)()!*$&$)$&)*
@r9205
CCATCGTANGGATGNCNNNCGGAAGACACTGCAGTCCCGGATGGACGCAAGCCGCCAGATGTTTGCCCAGAAGGTGTCGGNATATACCGGCCTN
+
(#*'*%)!!"(')$$%)"&'''!('+%#)!+%"!)!*$'!*(#+%%("%#$)&&+!()$&$+&'($)*"&)++')#&&)$*)&!+'"#!+#%("
@r9206
CGATGGTCTTCAAGGAGATGCCATGATGCCTCATCACTGTTGAAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGCAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCG
+
,&(*+&'+C/&E-+;G&D6%1940*92@67B#-5-#)18.9&6#$#!!;8?;%>H,*?$)(9D::"F"/52>&%9!!0A$&EG03$4E/.#83$'9',8%$7,A/'A*%)76*#0C-@"64+%F4<H#B
@r9207
NATGTCGATAGTTACTAACGGGTCTTGTTNGANTAACTGCCGCAGAAACTCTTCCAGGT
+
+$!)($%)'$)&%*"(!*'!!+(+*%#+++'!()+%)&)%)#"(*#!"!('")''!&%&
@r9208
CGTCGTCGTTCTCACGGATACTCACGCAGCGGAACAGTCGCTGGCGCAGCGTCGGCAGCTTCAGCTCCCANACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTTATCAGCGCGGTACCGGAGGATGGCAGCGTGATTTCACGGTCGAGCGTCAGCGTCCGGGTCTGGCTNTTCACCGCCAGCACACGACCACCGGTGCTGATACCGGCATAGTCATC
+
GC>G13@;G3<!#7GC7A=-&?&F1H'H1.5)%C&+*9C=C81+BE2%"(')17070-2H0@)%F-;%H*G&6/867+D*F-%-#@A')052;@$59=32)C2E9HH:1(G/:63&')<1D:8DB6!@*<3FH.>4$@;5H;DH"="0<(0BC?(,$FA<(?G4HCG-"H$BFHE!,D(=$5-C=(/E&D-)E-F4'#A<FF(8=>=,C.(>396>?A9?-"F&G?#:H18:,70);47*3,E4C:<2*7841/C>*ED,3D0"B%?:+.+%)?<&-8-)./*;F)55D3:1@G3
@r9209
AGTTTTCCGATGGGTTACAAATATCCATGAACATAAAAGATATTACTATACCTTTGATAATTCATTATTAAGAGCATTCAGAACNCTACACAAATCTTTCCACGNTAAATCATAACGTCCGGTTTCTTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCT
+
0)D.7(9><7)#?24;.(4++&C>"5")#,?;0DC*4;<430;F?H-,7;0=7:&"=H;'4810-&H(9E==)@@->**H8+7C8%!6**$&0;:7B%$>;,E19C700G?EA&:+<21((2#4:%!&7(F.5-##41,<;B/5EB-H9*B,A(<A+7=;7/7'1.D=.%>0"@/%+;3"&:
@r9210
TAATCTTCCGANTTTGCTAGGCACTGATACATAACTCTTTTCCAATAATTGGGG
+
&0+CG9%7>=)@1'))CC*&@1C;27*4!5@-=%:873G0',A&58,2-?$C/G
@r9211
CGACATATTTCCCATCTTCCATTACAGGAAACATTTCTTCAGNCTTAACCATGCATTCCGATTGCAGCTTGCATCCATTGCATCGCTTGAATTGTCCACACCATTGATTTTTATCAATAGTCGTAGTCATACGGATAGTCCTGGTATTGTTCCATCACATCCTGAGGATGCTCTTCGAACTCTTCAAATTCTTCTTCCATNTATCACCTTAAATAGTGGATTGCGGTAGTAAAGATTGTGCCTGTCTTTTAACCACATCAGGNTCGGTGGTTCTCGTGTACCCCTACAGCNAGAAATCNGATAAACTATTACAACCCCTACAGTTTGATGAGTATAGAAATGGATCCACTCGTTATTCACGGACGAGTGTTCAGTAATGAACCTCTGGAGAGAACCA
+
<B,BG3D4>364G?)8:AC-/$C/">=+'/=#)5$*?.8=8FFD@9"G@"-0:0--=6%>=""5<C;.*)'%)E7?$?FD</G097D?#$G00,=A<&?',".2.(B?6;<.65211>E7HB0B%-@5$8(?F?/F,+#03+247H-<#E*1:!H&-G8(2$4D-@=D95,4@-<B'G19!%*3#;C6'76C.F,C/%<H0>E-D($>$*";1?>%$6?30<#("D-4$=@H0"->D-37($/2.',!"&201<@0!!1.@>A":@'@,--0*H8/"0!.3?$G#%<-<)H!69G',#F2B5@;4'33D!%/>5DG$C=%,/5=<+5>4(FG6(%F&).%58G%C/=3B/0E>G7G;&8G::3&+-1=8/<65?83!*H">)A/;@>2B,3&C,>'-
@r9212
NCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACG
+
*>4<B21H,61*CGC"H"5?260F?'7-?5520)3/5;$D;4AG/)
@r9213
TGTCCGCTCCGGCACATAGCAGTCCTAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGGTGGTACA
+
G<"FF/7@7DH8A0(-)5D$'B@#A"A5DE<9#B*7"9C#35C=/#!G.#C7*<@"#8/$$->08A-":?>C
@r9214
ATTCCTCTGCTGGCCAGGATTTTTTCGTAGCGATCAAGCCATGAATGTAACGTAACGGAATTATCACTGTTGATTCTCGCTGTCAGAGGCTTGTGTTTGTGTCCTGA
+
H>)#:=@067-,>,D#C=%4-7@/B&%%*9"/C)5/?(E;A15EE+#"8;#C.9)75?/<>(C!!-'-*@70,'-,'?D70.2E>5'+>*;B/:AG/A!#>=?+(,-
@r9215
TGTTGTTTTCGTCCCGTAATCAAACGACGGTNTGGTTTTCGTCCCNAAAT
+
?.8E)&B?3,7C32337%+=8=).59*D5'</53)E-C#+,'A5DH#$CF
@r9216
CTTAATAGTATTGGTTGCGTAACAAAGTGCGGTCCTGCTGGCAT
+
&B:.!D&DC*5G/'18!'#.3$%:7?;C6C3%76/*C.=,#'G;
@r9217
TTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTTTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCNCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCT
+
CD1/E%".2C*8"9,9*?27;E7*B<07GC;9&<7,"2#,2>GDED5+&&/A)=4-9E?#:A%3!3'B/&>AH.@4.6.&)-6%6A"7?6-!*"?;+35#-)G=8,!53#*H"1)A2C<@H+5&A6-A+#8-
@r9218
GNNGACGCGTCGATAACATCTGCAATCGCGGCCAGTACAAAAGCGGTGTTCGCAATCTGG
+
(&&.-E0C3-$1)6$:H>27$)9<))/63##(+=3?'47<-5!3B4$A1;C!77D:E;*F
@r9219
TCTTTCATTAATCCCTGAACTGTTGGTTAATACGCTTGAGGGTGAATGCGAATAATAAAAAAGGAGCCTGTAGCTCCCTGATGATTTTGCTTTNCATGTTCATCGTTCCTTAAAGACGCCGTTTAACATGCCGATTGCCAGGCTTAAATGAGTCGGTGTGAATCCCATCAGCGTTACCGTTTCGCGGTGCTTCTTCAGTACGCTACGG
+
.$@5BB=$?H,5D.EAG)F8'AB2H89/B(&-8DE5';5HF(8(F7442B'6%E"+/0*<D;567H:,.%*?8%%+'"+),'+H1.$F0-""C677*"5%1B*5511DCH&!:!)A.;:'"AE,.1A=0=/A)3)(F66>A$;;GEE-B'71,=:EB-83)!46:FF4%2E,"65@67,(2<E=43&3;FB6":3#.'C6C1;9'CF2
@r9220
TAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCGCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGAGCAGCAGANTCAACAGGACAAAAATNCGCAGCAGCAGAGCGATACCGAANCG
+
<8#:1D14$,=/$)CHC5B#<D+(D&==(0/F39$?C,@)*?+7?,=C.,9B7F-.2<A5!7H;+6F<$:6'-/H&32#F,$->?@'D?@<7@;/"/F5"/A@BB'A!&</,&==8</!2/'&/=B?@$3B/;<='3%7AC,9.FA<#7,1@;,-D.;3C2@:%"7GG1-928:7-(58
@r9221
GATAAATTCACTAAATTGTTTTATGACAATATCCAGAAATATC
+
5$&8<'E885/6F/9?&-8-/E!,)9=-E(H<5/;.G#86'4#
@r9222
CGGTACGCCCCGTCCAAGCCAGAGATGACAACTTCCGCCATCATCCGGCGAAACCCGATCTANCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCG
+
*H-%7@*A=B&-&89!9$G;#<#%CD!)$2?1;=49?E&2+!%/&5515:")3.=E<B(/'/D#E0)-$5?%3H.%-64>"():4D=>AH5>80:"":1/*#>BC@,:F'7*:.?G.?&7#(=%>/-'?
@r9223
ATTCAGTTAAATATGAAGGTAATTTCTTTTGTGCAANTCTGACTAACTTTTTTATACCAATGTTTAACATACTT
+
;C2C7$6$5C=?4B@05B28"F$&=&,<&(./,B$;,BA*E?.F,(BH4<;0F5D,7-2:3)$+E'H?&'482E
@r9224
GGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTTG
+
8!'E2.*$-@-86(%9E1'2=?<&85!@&CC*1>D#54H.G6CB7>$.#8H-B/$@:A;:?&##0C"*8)$@,'
@r9225
ATCCGCATAAGCGAATGTTGCGAGCACTTGCAGTACCTTTGCCTTAGTATTTCNTTCAAGCTTTGCCACGCCACGGTATTTCCCCGATACCTTGTGTGCAAATTGCATCAGATAGTTGATAGCCTTTTGTTTGTCGTTCTGGCTGAGT
+
+18A::+34%@4==E,"1C+2#E4?:&?+7(B%"'GG$?('<*9)%$1A?:>*+01''!).)(37='??/*15E82/?"=52*5(HG1,6H83*:G!/4D'"?3E,C:9>#2H(7A.;/-&F0;GG-2B13</(?2':%,*/0?3!B3
@r9226
AATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGGCCGGGTTATTCTTGTTCTCT
+
"3H?)521),H$>47)5%5F+DE27>$?4*52*6<33D=2C1A3+E0,.$"%9-#=<@@*@)"*@*&CC%%AE#=,#39/>&41
@r9227
AGAAATGCAGGGTGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGNCCGGCGGCTGCAGATGCAGAGTGATTTGCCGTGGTGGCTGGTCTGCCGGGGGACGATTCATAAGTTCC
+
62()%=A7@$(4(2G#4:&,$@+0-.8,B@>6+5@/+<!F4B).0'3B9('437-28HE5B:!(9+&>BG(23$*3,A@)7?D9#"#<&68!7!8:1))4+&7=D/H99&B%6?(0B)'#=+*1?@!:,'4EG0&H>GED
@r9228
GGCAATGCCGATGTCGATAGTGGGTATCATGTAGCCGCTTATGCTGGAAAGA
+
5*?3?7$"@F5CH3AAE0)=H"%,.#3F(27&>$G<#;59"F/42D#A%6,0
@r9229
CTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGGGGTGATACTGAGCACATCAGCAGGACGCACTG
+
@F9=!/#&F(:'++/;'.B+(CFA.+%"D(*$;09%C94D31/+DEA'2?5</D/)AGB1398G'@2:D(54B>*!(6;/FB.&GD5.91$,10AG65,A1%7<53;GHF0G0*49>>)9@'
@r9230
TTGAACAAATTAACATCGCTCTTGAGCAAAAAGGGTCCGGGAATTT
+
$B>E;6'+C@G/+3B+-6='6@D)+%56C>B*(H'(@,744&-4#/
@r9231
GGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATNCGCTGCAGCATCAACTGANGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTGTTTTTGATGAGGCGGATTTTCCGGCAGTTGCCGTTTATCTCACCGGCGCTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTNCATATCGAAGTTTTCCTGCCTG
+
GG"#)*C!HB@,65/GBC45E:-49=A@15&:!G2)F#*%<<"DG!(E7.2@>6.0-2=;826?3,?E-=1()4"#@4$"<.82?21!-""="/&%1C;/.4!%3<8+)6/>)CA@#DF37=<*C%C?$:42'B,1*>:3$,1$(70475!26*:?2B.()1*>8D685$)#,2&D!0'0=2332(+%=/D4E30<2@(7$ABH6F4%6*@<%@<?9*;/*89&53*7.7%F5C*C$1($&+?*?C*#E6(5)B)F@*+0EBG6--7+E3=,@-?"-2-$*>!+*0A6'BG&8=9E:C<$96.G%:5'><CD!)G-(>=120=
@r9232
CGCGCTGGGCTTTGTAGGTAATGGCGTTATCACGGTAATGATTAA
+
8,'7D!./&F(0#>B8?;'3G&"8+?=-7@&F1/6%'.F1.>4/A
@r9233
TTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAG
+
7383$5&5.&+6#G36&C04*>#&*';A&1@@$@<!>+-65@G9&,2*(!/+;/4&E,;,!>F
@r9234
TATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCA
+
.F!H3838#H$$*67*+863.5'5-G&()#55#4818FD0:@1,F!A7="38?7
@r9235
TCTCTGAGGGTGAAATAATNGCACGCCGTTCAGCGGTGTCTGNCGTCGGGGGGAGGC
+
?""9E%%.8BF193=)4-0,?%,+;=0&1>C5#=;499G)&2-6$?2E)%43"D,8"
@r9236
GNAAGTCNCTGCAAAGCCNAAAGTATGNNNNNNTNGNCCCNANCNNNNATNNATCANNNNANGCTGNNGNCNTGNANTTNCNNNNTNANNCGGANNNAGNN
+
$"#"$!"$#$#"#!$$$"!"#!##!$#$"""##""$""""""!##""!!##$#!"!!#!$$$#"$"$!""#"!"$!"#$$!$##""$$!"$#"##!"$!!"
@r9237
GTNACTNGNGTTGCNTNTCGGCACTGATGAACCAAANCAGCACAGCAGCACATCGCCC
+
*'"#&&&(#*$#%##$())+!#'*"+"%($)$+&#$&"*(%!!"!(+)*%$&&"*!*%
@r9238
NTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTG
+
!+!&%%'($#+("''%****$*"'#*&*+'%)(+""%)$)!+!&*$$#$
@r9239
TGTCATGCTGCCACCTTCTGCTCTGCGGCTTTCTGTTTCAGGAATCCAAGAGCTTTTACTGCTTCGGCCTGTGTCAGTTCTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAAC
+
<=D".@G2@7F/H@&1;23$:*22CE(16!%(CG!%>DC<<G.-5EA23"54-)D@F")AC%)'B7"E1#)8?9'6G/#-F"/;-)%G;8,(@.$'G/&G"B5<%29:"><("5&(&*
@r9240
CAAAGCTAAGNTCGGACTGAAAGGAGCAAGTGTATGACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTTGCCGCGCTAACAGGCGCAACAGTAACCAGCATAAATCAGGCGACGCGGCTAAAATGGCACGGGCAGGTCTTCTGGTTATCTAAGGTAAGGTCTGGCGAACGGTGTNTTACCGGTTTGNTACCAGGGAAGAACGGGAAGGAAATANGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAACGGGTATTGGCGGTNTATGGAGTTAAAAGATGACCATCTACATTACTGANCTAATAACNGGCCTGCTGGTAATCGCAGG
+
'5*+-F9;48C$>5'%<$$.%H"%E?>;.B/*3C+"83"8,$1$H"05A6BB2(4"D.3&#@4B)E3D;9#-%C*:B2A6@8!;#=3#*-/A#,G$%A:?ABB$(1='/H:H0<22,054C4$27/"8)':?7)'/;>9/#=E:-0<2E2"DHF2)DB37+E3+9/0+%CD-6=8EB)?0F8:3#+A063+34>?:>=''2F(C8"@>37GF+=DC#95B#?-&?+B=,A<7,9;+1;)CG67'*!=*C*<:*-.0G??0(+@BG:6!2-+&%8HB*8@DF>$1C!4,@E!6=3188BFAB#!6A0A5F:B-%62#!51AB@5=DH+:H0+HHE?#"*"6:&"0?,?GH<%&"FC(4F46F3"C6-?%%C-E
@r9241
GCGAACGAGGCGGTACAGGTGTTCTCCCGTATAGTTGACATGCCAGCGGGTCGGGGAAACGTGA
+
::(2;"?3&=D2$10E:()=$D"1AH"+:H#=?)G+?+G>?6";?>))%!/920E-8-F4>@16
@r9242
GGGGGGATTGAGANGCCGGACTTTCATCGTGAGGATGACTGGTGGCGTAACGGCCAGAATCTCTATCTGGATAATCTGTAGGCGACGGGGCTGTATCTGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGAC
+
64)?F7%501E$2,!">!&<F,D4#5+A;7+2-<A&;2E3=-G.(5B$<F*=G::*.<,%#D#*(G24*G1D2*-'-E'(H5*@<)HH76;-9'3%/36??%@"/G&6%*##D@26G0G'BC!%*%-#*.;C(=(&G5B=4)5D<47,?5G:%06@.<)!.$1>C6!H76'@;4(="6G>@:AGA%&G2
@r9243
TCTCCAGTGCATCCAGTACGGCTGCACGGAGTTCAGTATGT
+
?.E6D0=-8'(96H@05E27387$&!56'&(&AF2H3B*%2
@r9244
AATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGATTGCCACGGATGGCAACATATTAACGGCATGATATTGACTTGTTGAATAAAATTGGGTAAATTTGACTCAACGATGGGTTAATTCGC
+
'8"+<;#0F;3&@:08#E)+#"F63E..#9$8C%@53%5<,1-@#A/$:-2-0?+4+>8%;..';3H3G<&-77G"E9<?6<$?+>1"-?=%10=B@30DC#F&(A0+:&B$>(6/=694:7E2:H+)A&:1
@r9245
CTTCGAATGAGCTCTGGACATGCAATNGTTTTATTTACTATCNCAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAG
+
D9H1,#/@>D:G,'$091,E=;#'*7G=!*&:A2'1&H<5/:DF-D+<-<<(!G9C6?<=.7)2CH8'F@1G/!?0<9=
@r9246
GAAGGAAGAAACCTCGTTGCTGNAAGCCTGGAAGAAGTATCGGGTGTTGCTGAACCGTGTT
+
E/H#*F-"'#19!D<%.@.EG>?)0:8?B84C?6!/(C->8524D<&@H&'0G+2G1)#"!
@r9247
GCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAA
+
HB;-C,CE'B%'F6=!%F'(%5A-!&<5$+*#93A#/=F73?",+";
@r9248
NNGNCNNANANNGCNGNTTNATNNAGNTNGNTANNGNNCTGANGN
+
$"$"""!"!$!!$!"!##$!""""$"!##$"$#$"$#$$""#!""
@r9249
TGAATCGTCCCCCGGCAGACCAGCCACCACGGCAAATCACTCTGCACCTGNAGCCGCCGGTCGGCCTCACTCAGCCAGGGCAGACCACCGGGGTGGCTGTGGACCAGCGCCACAATCTCACCNTGCATTTCTGCCTGCAGCCAGTCTTCCGGCGACATACGGAAATAGCCTCCGGCTCACCGGAGATATTCACGCAGGGGAAATATCTTTCCCCCTCCGGCGTGCTTACCACGAAGCCGCACGACTCCGCTGGCGCACATCGCCGGGCGTG
+
H)A9/%)A(,=,>"="$$"2F.,'?/.(9%:,F5/.&/)&)8:)-?9E;2-*7@)=+<C.E9C8:.E40-;!;-E5))7>"!9F13,44'CEA"B*$%'5!@G%(1E>=FF$C<;F18C("F<9'C:"494C85?3B5-=H1:.9?FD5>?D?@621%BB-2$"B#*179'F-F0,@"D4E9+/#,1&5D.G66-"'%A"B=<H4*C*C@>09*F7-+-E##9"@G-&?#3&.*$CE)7G#8G):;5*=$504/5#2CB#@C;3?4(7%2)
@r9250
CNTTNACCTGCGNNCTGAGTGACTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACAGGACCAGCATACGATCTGCCGTCAGTCCNGCCTGNTTGCCGGAAAGGACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTGCCGTGATACCAGGCATACGCCAGC
+
)#)*%)'$&$"$&++(&+'"*!)#)'**'#!&&%!)**!"#*$)%'")$%%+"$("+($&*&(!&*$($()#%$')%(%+#!("+&&"!'$'&%"%"$&**(+%&*$"%##"%%'*+%+"!*#+(()#&'*!#%%&"((+"!(*%+&!%$'("("%%)#$+!$$$*&("!''+*%!%!*
@r9251
CTCAAGAATGCTGCCANCAATAGTTTAAAATCACTAGGCGATCTCCGCTTAG
+
D!C">H:@8,2/<1GA1,1F8@'H*/@A68;G+><!6D&8F,.H,DBD$,$-
@r9252
ACCTTTGATGGTATTGCACAGAATATGGCGGCGATGCTGACCGGCAGTGAGCATAACTGGCGCAGCTTCACNCGTTCCGTGCTGTCCATGATGG
+
'F6<3&A2,/;)28,BG$8:4+1G=.95B4"+2,H;A+D@/$6-&G:1C$-&1#90D<?B(@'%/EB;/1)"H652'6%>C8$;0.:'&-+:%1
@r9253
AGACGATGATGCAGATAACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTNAG
+
*F=CGB2=3'*3/C:.:3H',451&?C!,6%,@***7832%2?#@F>F9#;&!3&>C.;.8(G?2@*;#96::F4587#!,%.8H(!C(!:06;(/2,*-&:0!5B;%@6
@r9254
GCCCTTAAATGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCG
+
,7&$B//&2?,109>>!1DE(=E/:"3"436275(937)%-2>-5%3D%H<.@)F6>EH"8/<,D#=,/.+.FB15>=28?&*<G=B9$"*D4#'$F$08+F8C7#A4#<EGA"-/1/:+,)!*E+C0A$?3:>E
@r9255
GACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTGAATACCGTCTCAATAAACACGGCT
+
F3?',!$5;(;>-C>1/C96!<7?D.H00B:H-6('6+6'BC>-46%*6H;-H49<-<$@!E@7#6C/H-:
@r9256
NACACAGAATATGAAGCCCGCTGCCAGAAAAATGCATTCCGTGGTTGTCATACCTGGTTTCTCTCATCTGCTTCTGCTTTCGCCACCATCATNTCCAGC
+
#?//'/@BGBBE6$"(1#:?'=3@:%C86=.4!/.1/9%EC:-72/=;(D,3B+-0*C9>A:B)G1@-737$,&-C9'"E$CA9;4%%"9H:#*%=,6.
@r9257
TCTTTCGTAAAAGTTATCAGGAAATATAGTTCCACCGCAANGTTTCAGCA
+
$?.<&($"B$B?<609)9=G?4EAE%:;%#(569%@%'H@.1/@9)0EA+
@r9258
TGGTTCCGNAANATGATGACAATGTCGCCCCAAGACCATCTCTATGAGCTGAAAAAGAAACACCAGGAATGTAGTGGCGGAANTGGAGATA
+
(**))!'"!%')+&+%'#!("++!&)+(*+%%"#!$#&)&*&($$'"$&$*"$'**'#'()&#%*&$$*'&#!')#&"+"&$)(+!)$"##
@r9259
ATAGCAATTCAGATCTCTCACATACCAAACAATTCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATA
+
,75'%A0B%=6,;;@.3&2GG/7#>D0*&A'=>3B;F)@B+:G+/)*DCF2E$0*F/25%;<H+G5>-@19AA40$
@r9260
TTNNGGTTGTGGTGATTGGTCGCTGATGNAAAATGTTTTATGTGGAACCGCCTGCGGGCGGTTTTGTCATTTATGGAGCGTGAGGAATGGGTAAAGGAAGCAGTAAGGGGCATACCCCGCGCGAAGCGAAGGACAACCTGNAGTCCACGCAGTTGCTGAGTGTG
+
')!!*++'!%*$')%&!('#+)$&!%!(#&$&$($&$+)'%#&)*#**$%"!(*+*#+++"&(++!++#)"'!*%#!+)()(*"+%!+$#'$&$(''&!'"%$%#!+(#''(#")()&$%+"#(%"&+)#+(%($')"#(#((+)&*$"%')'%*&(&%$%&)(
@r9261
TTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGNTGATTGTTGTGACGCTGCAGCATTCGTTTCTGACGTTTTCGCCGCACCGGCACTGGTGGCCGCCGCGTTTT
+
:=*H?><,&&,=A:00$6H051BA!.7$+#*D&;B7=?HF?/G85=1*':'0%D%:6D@:FA@6HF@(DA$<="+*;4*+?8,/%#;E3!73,.)B;C)%-'+3
@r9262
AGGTCGCCGCATCGACCTTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAG
+
#2E(''&>+A#/',#:E*5<'29EC33E3<<5E=/->3*'3*!6<(>?=.</>/";;-6;.AA6
@r9263
TCAAAACGGAACGTNCCGGACTTGTAGAACGACAGCGTGGTGCTGGTCTGGTCAGCAGCAACCGCAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGNGCTTTCGCACTCAATCCGCCGGGCGCGG
+
;FF'@>"C=?<20?6()#@;&6<#4)%+>H1&8A1H=>G00FD1!1$2+1!(?$&(G7#;%+.B26C'27GF6)EE2H=.$80-'+:!#?2*-;D+F$24:?<F:%;5@*+=8/7&0E7/84!::"(H$(D-81A-.D!9/4*4$+B@:+&#$+-''!5E;6"9C6+-!+F#B!A$*!HG'H#=
@r9264
CAGCAAATGCCTGAGCGGTTGTAAGTTCCGCAATAACGTCGGCAACTTTGGCGGCTTCCTTTCTATTNANAAACTTTCGCAGTAAATCCCATGACACAGACAGAATCAGCGATTCTGGCTAGCACGCCCGGCGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGNGGGAAAGATATTTCCCCTGCGTGAATATCTCCGGTGAGCCGGAGGCTATTTCCGTATGTCGCCGGAAGACTGGCTGCAGGCAGAATTGCAGGGNGAGATTGTGGCGCTGGTCCACAGCCACCCCGGTGGTCTGCCCTGGCTGAGTGAGGCCGACC
+
A@G;4698:"GED0;*<;&&E-3??*!E+.E6"=*18")4@9H(31&F1A!E<".?6D-9+-!$0@>B@-<&F#:>:1F%+7H/A3'=&"F<!92/$A3@1(36G30!H4B,7%67"23+()45D>#,3!;&5D++.=E$=4C)&)-$C6*)':E(D&9?/C<88-?21":)6&=3EF-=8/&9($*(6,(4'6C=@$D?90F,"8@#@0%1?%?-?C+(>4F51/?5H$F!!E-3EE.9@>C(B7"D+%4(<EC$BH4*!=/,A0)9?2,91F+*/1-!8!A=:/?2"7&9!C4B,2ECE;)#6!;%0)@+3A>9>1*<=3<-B0<?:"A"6$?
@r9265
NTAACGGTTTTTCCCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGTTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCACGCTGCCGCCACCTTTCAGGGATGAACGCTGCCCCTTTTTACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTA
+
!.CE-DG/%//$2A,E1913-)A;7A8607(>.=F)+*970(6*G@/?C$DFA%";*@/'3/4&FBA23&9?DE",?'E%'+92*+).%0&#&D%1080??B%#+4A556-1-/#/;#'D7+;:5DAB9':/E&7EGD0,2*7-+;*:$F!C*!/,"%2='*%'D97$:D/%CG3+&:FB<<)#%19B==;
@r9266
CACCACAGACCAGCTGCATAACAAAACGCTCTGGTCGTCA
+
='AE7)<4@016-/(GF1*CC,G&/4='?9=4(#=,1;*)
@r9267
TTGACAGTCCGGGCGGTAAATGCGNGGGGGCAGCAGGGCGATCCGGCGTCGNTATCGTTCCGGATTACCGCACCGGCAGCACCGTCGAGGATTGATCTGACGCCGGGCTATTTCCAGATAANCGCCANGCCGCATCT
+
$D8./-"76:.#$)C:3C,=)G4.C4:A#C$05:1"3#*?AF/?2#F2<!9<@((>>$&B7E&%H>!0*/.G$&3;2B,DA-@(A+D?9C247&/%!=5;3B/.5(E.2??5871D2A1=6C9*71#/D7?('6HF9
@r9268
CCCGTAAAGTGATAATGATTATCATCNACATATCACAACGTGCGTGGAGGCCATCAAACCACGTCAAATAATCAATTATTACGCAGGTATCG
+
++%*(+*)!'#&%)$!('+(#+++*!*!'"('#"'#%!$!(+'*$#')*&"&%+!+$%)"'#)($%#+&%((%!((%&***'#!*!%!!&%'
@r9269
TCTTCGCTGCTNAAACANCCGGAGTAGAAGNTGGTAGAAATCAATA
+
+*+'*+(+"#$*%#((#+*((*))'&!+*$!!'&&"'$')*("(!#
@r9270
GCCAGAAAAACATGACCTGTTGGCCGCCAATCTCGCGGCAAAGGAACAAGGCATCGGGGCAATCC
+
8'7/D",51A&%#1G5E@.H*#@:0?4*0-8F%G.!(?->E?#:F$H>7=AA?G!H.")9D)2)-
@r9271
TTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTGCGTGAACAGGTGGGTTGGGTAAGGNTTGGGATCCCTAGCATCGTCACAGCGCGTTATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCC
+
.(0.&*&H/"/0"D3A9<@=/"*GF&/@+)6-B1"07=#B";/954EFG;%?"+*2<(:H(4(-%=C48)GA>/-F?D$;B.#E;173.8;+"GA7EF"@)<-E31?AHG"->@.;/(?2'3@0@5$A59*=4%%./'H)"2A2.@E>.A1G'.,#C9&)&!2E*A.
@r9272
TTNNCATAACAATAATGTTATTGAAAAATGGAAAAATGATCCANTAATGGCTNGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATNTATAGCGAGGCAAAGGCTACTCTAATTTCATCTTACATTGAAGAAAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTCAGACTTGCACAAAAGAAATTACCTTCATATTTAACTGAATCATCT
+
"**#!+''%'&(+'%)'$(+(")"*)%#%!+!!&'$*++"($!&+'#$&$$*)""'$!)+"%&""+'(+%)")"%&+*"&!!+$+#&*$%)!&(($)&!$+!$!(*+)(!*%+!%&)'!$#'+(!)!+!*(#%#**)"'*+*+!'*(#+''*(&+#)!&''*++'("&+'!!&)'$&&*''%&(+"'!%(+!*%+'##('#""''%#(*!$$#+)"%"*#(")"'")$+$**&%!&$*!%+)%$#!&"+#"#*
@r9273
TAACACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAA
+
)BA4H4+3'09F=@:/H-&$-'6/D5&E*/!7D"<;&B1H0$:-588G0G?+3@,<(=-&&$D6'$>DE7#80&F,C*'
@r9274
CCTGGTAGCAAACCGGTAATACACCGTTCGCCAGACCTTACCT
+
>'*D92(&(A!H7('6"(,4)5F-0C&GD01C24)2&6A,0:'
@r9275
ATCTNTTTNNGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGG
+
)$(*%(#&)$+!('(%&("$'$!++%(*$)(*+"('&"$!!*''$%('(&'+'*#)""&
@r9276
AACACGATGTGAATATTATCTGTGGCTAGATNGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAA
+
93*D?+/8<?H""0H$?1+@#8E/<+BHE&$-G3.0B5/D06$;4*G%;%G)4:D?B@F-94BC;44#2><A
@r9277
CGGAACTGCCGTGCCGGTGTGCAGATTAATGACAGCGGTGCGGNGCTGGGATATTACGTCAGCGAGGA
+
?'(,D$G.+%3;8-03*AD2"#$4?=&&1=/A:4!30BE!07:7?<*6A("E"#8&$7/<##'(&A),
@r9278
GATAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCNAAGACGAAAACATGNCACACATGAGGAATACCGATTCTCTCATTAACATATTCAGGCCAGTTATCT
+
1?E=65.%;13@5&2/B6$!:6())7=H(',/G&$,>=D"F?*-.D?@&*#H:%"&G@>)77C3=E+3B(20E(!<9>??-)6C>*"/,H@'H3:(0"5E&"61<'B1
@r9279
CAGAGAGAGGCTGATCACTATGCAAAAACAACTGGAAGGGTAACCTGT
+
.1.E8(7%79F<DG&-+(3,31'=$%4#?!'>D#?+B;/60+(+C'::
@r9280
TCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATANTACTAGCCGCAGAACGTTATTTCATACAACGTTTCTGCGGCATATCACAAAACGATTACTCCATAACNGAGACAGCAGGCCACTCAATATCAGGTGCAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCC
+
4+>#F*;E(B;0?4:@%#,-A"?%-0)%1?8"-)H*D/!;&-(61*C-04$,)#9.#'=*8/+.G)->@2(G@@8,>>E<939E:-9+3A")84&B4B'A$-!'?='EA455*(-C;83<E>@.E40*!7%>&$AG'24++-/<*>9=,40)%>#&4>%<GGF4=7B;F7>$&6)D3+:D<+':+G00).>#6&2?:<:<2?
@r9281
CTCATACATACCAGACAGCCGGTACACCACGTTTTCAGCATGAGAAATTGCCTCCGTGGGCCAGGTGGTAANCACTTCCTGCTCA
+
6#C5<@30=?/'<E7=6'"?081!.=6A5'")#F#<4H2A%(-E;BC03(1:."C6E=-&D$'5-%/#H"=?1*@AA.>+74=%B
@r9282
AAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGCTGA
+
;>.?H1,+.."7D:%@<-'2<<3E&G.)>,6*/#"1,0%$?(
@r9283
GCCGTAGCGTACTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAA
+
('+''&+'&!+*"%%('+'##()")'&(&'&"%"+'!%('"*$)$#"(!($$+#&"+)*&*(&'#&
@r9284
GTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATNCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGNGCTGACA
+
8:5;%(#13)3+))H%+6C85H,B;7.2-G.=A%,+B(CCA,FAD8,H#:%>EG@E8'#,19)1@;$D&A&9D&38<5,915)$9?<C)"E!>##>#FA>D341B31??8BB>4.G<=35
@r9285
GATCGCTGGCAGCCTGTTGCAGACGGGCGATAATGCCGTTGTAACCGGTCATCCCCGAGTACGGCTGCAGCGCCCGCGTCCGGCTGACCAGCGTGCCGG
+
+$($"%%%!$&'""*)$)(%*)&!+!#"%&"$#+#!%%+$"+)+*&+&"*+*)%"++%+)+#)&%!$"%%+%%!#**'+)''$#'#&&(&''%+*($)*
@r9286
NNNTTGNCCAGCCTCGCATATCAGGAAGCACACCCGATGGATACGCGACAGCAAGTTTTGGNTAGGCTGGTTTGTCAAACGCC
+
!#!(')&&+*$)$)#$'%"!(##!)'(!(&$&)'""'#)$(*')"%$'$(*%#(#+(&+&'&!#)$!%'++*"*&'''&(*!+
@r9287
ACGNCNAATGCTNNGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACNTTNATGGTGGT
+
&'#&#!('+$!*(&$"!&"#(!*+!'!+#!""((*"+$"+%$)%#$%$$*%'!)##!&))!&+"+$((&#"++"(#$##%%)&$'*)$*)+*!)%")$%**+
@r9288
CATCGGGGTAAAACCGTCTATGACGTGGCTTACGGCGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATTTTACCTGGTTATCGCCGGGAGGGGAATATCAGCAGTGGNACGGCACAGCCTGGGTGAANGATACGG
+
@B7B+C.@DD@-G)7'A"?;/H:8>F.%%44-!"D5"0>/63&14F'"#-FD0*;.+$H%77#=C-/0'3B#G;20HH52+(09(1C265@!2400;21*+B=A%EE<;&BGACC$&#=;=,$+5%<);'A--D#&35+(GEH')
@r9289
CCACCTGTTCACGCACTGTTAAGCCGCTGTATGACGCTCTGTTGGTGCAATGCCACAAAGAAGAGTCAATCGCAG
+
961",=-H+90.+*>'29=7F>BA03A8&<90,G+49'%E*-G$)!3:?;)E1/F#6.2$*"@@D6-+H#,$?/.
@r9290
GGTCAGCACATTNTCCCGNCTGAGAGGGGTGTCCTGACCGGCAGTTTCATNCGTGTC
+
:=&9D!*5(=!F><3,EA->G9B22<E&+F3##6<*.;G'6DB1"D7679E=7+0?H
@r9291
CCGGAGAACAGGCCACCATCACGCATCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGC
+
/'D5=*4E%?#;3.*>!&3$$?92H5%&#6!"#;B!9B,@,(E0D2HC547G:3"<=4#3@98CH>G&F<.8$/D('1&<C,52C6
@r9292
GCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCA
+
G!3D5;'%7BD0'5(@9;=1?BA8D5!5.9C<<A5#/38GB+)-$781(618);9@G<A!2&7BH/@G>0929G3=FD9--($FD:<C=C9)
@r9293
TNCCAGCAGCTCCTTGCCGAGATGGGATTCGGTTATCTTGCCTTTGAAAAAATCCAGGTAACCTTCCGCATCATCGCTCGCCCGACCGACGGCCTCCACGAATGCNGATTTGCCAACGGTGTTCACACTGCGGATATAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGC
+
*$C'A(A'/"13E70@,GF3&?:H*#,9,%%1$:8@>220!F@"@A-<9@0H7,(0:5'-H>&90.;#?:;8>C%$)A,5A+0(($2.GBF4247A!/'%F%01=8(:-G/1E/'6'!++%&=03CBE6*$+-473&/68F7D?841H';D*+&94/8;F>;;#>.DH%F5&';&00
@r9294
GCATAAAGCAGATGATTAATCATGGAACTGGTGAGCAAAGATAAAAAATATGTTATCTGCCACGCCGATTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCANAAAACGGGATCGTGAAAGAAAT
+
6,'/,G01+4?H##G3C(A,+954#H(8%1>(A7A(/B2.70<2:!E<=9A:2)20)&7F7>C*+F4>B?"1<696?D6F@'<*G,-H0*8$-00!=:(@>*&>!9C+*?010A./G9="=7</!$-C@E0,%:?B2(CA.5D&"A"+%6#H/'3.#00#@=C2G;#4F@62"
@r9295
GGTTGAGGTGGATATGGGCCGCAGTGAGGAGAATAACATCA
+
3.(H.C*9D'.">6@/%:CC<,:5-%%=<"46#4!8D-37=
@r9296
CACCGGCTCCGGCGTGGATAATGCAGCCTCCCCCCGACGGCAGACACCGCTGAACGGCGTGCGATTATTTCACCCTCAGAGAGAGGCTGATCACTATGC
+
/=.!;;7#776-0,0?'C->!'%=A$<(C%E+90,C.47+;)8?>!::'C8+9B+?B099@':;11'H-E.-&A)0?-*6;F9;4C?1,,)G+',%#.E
@r9297
NGGTGNAGTTGATGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTNTTCCTTCGTTGCAATTTCCAGNTCTGCAGCATCCTG
+
!-">:8&#6??69$E&B@5C>4F4.G(3D2);!)90:-<++/&65*6<$,/HG3C"./+8$$889F;5ED$B=-C@H2-#):=$!!$H!ECH#.(-G#7"98?7!D"#
@r9298
TATCGTCTGGAACTCCAACCATCGCAGGCAGAGAGGTCTGCAAAATGCAATCCCGAAACAGTTCGCAGGTAA
+
=(/88==0C:0@#!G+$@H)@!(791C:F&5!*F"(4*8H7@?C:?,;B-6;H8&G;86'7F?!;+>:>#:7
@r9299
ATCGAGATTAAAGAACCAGCCACCGCCATTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTNTCCATGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCA
+
844<H.@G@9$'B/%E*-"*>;@-:9>.=4A/96&'@%:2+=>B;2C35%?A/0H'$007$8C5)B"#6+;#!4(=@8C*-G%!47&D-8)E3'2$';0!)3F"'GD"!+</+&>4@!2(H<7-0?<4+E:>=!<4"0
@r9300
TNNGANTTGCACCAGTGAATCCCCGCATTTTATGCGTTTTCATGTTGCNTGCCCGCATTGCGGGGAGGAGCAGTATCTTAAATTTGGCGACAAAGAGACGCCGTTTGGCCTCAAATGGACGCCGGATGACCCCTCCAGCGTGTTTTATCTCTGCGAGCATAATGCCTGCGTCANCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTNATATCTGCGAAAAGACCGGGATC
+
&"$$!!%""$&+)%**)$#'+$'$%&"!%$%%%')((*$$"*))%&'#$)%#)%%%#'##&&*%)(%""%")(#&#*%"!#"%"++"((+*#"'&!'*+&&*(#(!'&%'(&%&&&&)+!*)()%#+"'!*)#*'**)%++!#!+!&+!)(!*+!%"%(%('$'*!!#&)"$$!!#+('*#$#%(++&(#'!*))#!()!()%#"(*+"*'""$%%"$$"&*'!'&*+"%))
@r9301
TTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAANAATCTTCCGAGTTTGCTAGGCACTGATACATAACTCTTATCCAATAAT
+
DBF3&%6D($8$#@9'=G*&0,7-@=2:>0,C3./?$A"$F=6B#3FE3GH860&3"3>84D!<E#7%',DCF<1!G/8=AH'.%5,2<3/3#.:.*G)37;A>
@r9302
CTGCTGCTTGATAAATTTTCAGGTATTCGTCAGCCGTAAGTCTTGATCTCCTTACCCCTGATTTTGCTGCGCGAGTGGCAGCGACATGGTTTGTTG
+
0>2FHDD7C%<8$AH$0D"H/99$$-'2(/%:+7G"@<,AF+13A9=HE6:=6.+#><.8/;>5/>D,/H@CF65='A)0-351"&/E6(.!64;2
@r9303
AGGTAATTCCATGACCGCACCAACAGGCTCCAAGCCAAGCTTTCCTGACGGAATGTTAATTCTCGTTGACCCTGAGCAGTCTGTTGAGCCAGGTGATTTCTGCATAGCCAGACTTGGGGGTGATGAGTTTACCTTCAA
+
A/8/<?9*?994*9HF7>BD7*5H0GFB1E*?5.;"=B("@3%A#@F'505+;9B;G536+,C#81D1%!&8,%G%EA>1%=/1!G969'''-;3(8B/3%C%B"+.,+@F59?);3#F;-3D.F3A6"HEFA)*:=A
@r9304
ACCAGGCATTTTTTCGCGTCACCCACATGCTGTACTGCACCTGGGCCATGTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCATGGAATCCCGGGAGGTAAACGGGCATTTCAGTTCAAGGCCGTTGCCGTCACTGCATAAACCATCGGGAGAGCAGGCGGTTCGCATACTTTCGTCGCG
+
<.!,;0%&!C>&GE2"$!,.C..G25,,%#,11$7-+65$H&$+;1)EB*6EG>C&<#4(:"<1G1>;*F9D!2,E,)G6:-*HG643BABC<7+?C9@;$D5%?:)6#84;9C<@/.5E.<#.4@#@C$:83!"<7@@E(=051'DA/CF)D@9)$=0*;A=53@<()B:<:(,,A#(/9C72$'61'9
@r9305
ATTAATAGGCATCACCGAACATTCAGGATAATGTGCAATAGGAAGAAAATGATCTATATTTTTTGTCTGTCCTATATCACCACAAAATGGACATTTTTCACCTGAT
+
1%)8H%6%-0@!)-;*6DF'6)6$<C2;,'E<>*::%-=:/(BF<7!299.9F>&>GC)/8*'AE5B<2BB>2F#$0:452HEEA&<1&E%0.,"6=&E$$=3@69
@r9306
TTAATAGAAAAAGTGCTCCCGGATTCAGTGATTTAACTATACCTTTTGAGGTGACGGTTAATTCTATNCCCAGCACGAACATTCATGCTTTTATCGGGCGGAATGGGTGTGGTGAAACAACAATTTTGAATGGAATGATTGGTGCAATCACCAACCCAGAAAACAGTGAATATTTTTTCTCTGAAAATAATAGACTTATCGAGTCAAGAATCCCAA
+
*E/;>?#&H"*!)+.7209>1A,'0?H617=5"2A;E15'A92/%,,?DH)FB:G+11E(;6$C.:B?:6!F::%*,C8*/7(0$?-&.!34"+47A9%'3*7'"DB?+E3249=,B>'/BF%@(G73-?)B64%,%%D)80@G+98(0##G"&5B84-+?7!8C%#*&'$4?139"3(,,F*23B"7.-0)34G$=4*A<*<!*,>BE*!;5!03
@r9307
NTNCGNTNCACTCCTGAAGTGTCAAGTACATCGCAAAGTCTCCNCAATTACACGCAAGAAAAAACCGC
+
##!&)#*$+)$+)+!!+"&()+#%")')(%!)*!')#*&)"%$'#)"$!(%%%*$%$##!)("$(%&(
@r9308
GNANAAGAGCAGCACAGTGATGACCGGGGAGGATACGTTTCACTATGAGAGCCTGCGAGGACGTTATGTGAGCGTGATGGCCGGACCGGTTTTACAAATCAGTAAGCAGGTCAGTGCGNACGCCATGGCCGGAGTGGCTCACAGTCGGTGGTCCTGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCNGGTATATGAAAGAGACGACCACTGCCAGGGACGAANGTGCAATGCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGAC
+
*'#!+(#$()#%'$())#&%(%*'$+"'((#%&&!*#!(+$"'"(&$*'(+#))#$)*!$*%(*(&###*+)!!(+!&&&+(%+(!!)'$*'))'+&#!)*))*#")""&))$+#)#!'(#)&''$())&$&""!)#'*&*%$"#+&%&*%)#+!(&!$($(!(+"$!'!'"!#!(**%$'%&'&"!)"(!&"%*)!()*(*%#)*+'')$#$+++(#+!!$&*#)()+'#'&'''))!&%*!$%)#*)))!+&&!*()*$!'!$$''*('&("!#!'('*+(%!)*+!##!((#''$%!)$%"&$)'#%+')$$!('(%"%$+#')+#++$)#
@r9309
CCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGATCCTCCTGGCAACTTGCACAACTCCGACAACCCTGAACGACCAGGCGTCTTCGTTCATCTATCGGATCGCCACACTCACAACAATGAGTGGCAGAT
+
A*'&13CF*8:*'4)%85:,7-'B04#>9'943!+$0!-&@5*E'D&8'*&/>0F38H/&C?8&CC$$%&"78/$C@!=&0':)7(BA=$!":;"4$A%GH=H.'6E1C;A(,(&#:2",:6F!(C&)9+F&<&,=<@=/+$&#B"1.HG/9>GAG-EHH).:-2!!7A:(@9D(>%G7G<8E3E,<$&0)/9D=B"<8!!5#%%1934A777EGB@#"<DA'/0(23-D:BB=;+:F5)6C1+4:*C9")+:
@r9310
AATAGTTTAAAATCACTAGGCGATCTCCGCTTAGAATTCATTTCAGCAGTTATTGGTTGTATGAGAGNAGATAGAAAAAGACAACTCTGGCTTGAAGCNATCAAAAAACTAA
+
@0<B:9==G@+."-+00)/-&-!#%$30C"C3<-G3=:9<:8=E%,!*+2(00=#A62/(@==5A#*1B/EH:>'8/;>HH4G8&;E4#G!HHD)899H/,(1E3A4@!=D$
@r9311
TNAGGACTACAACTGCCACAAACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAA
+
&*;H8*4B:%(+"@"6H3$-"7+<3#1%==@(&:%!/!>#.E!74B/1)C$@"E>3"AC:@@B@7
@r9312
AGTGCTACCCGAACACGGCACTGGTCGGCGTGCAGGTGGACTCGGAGCAGTTCGGCAGCCAGCAGGTGAGCCGTAATTATCATCTGCGCGGGCGTATTCTGCAGGTGCCGTCGAACTATAACCCGCAGACGCGGCAATACAGCGGTATCT
+
.,*H)/$7&A42C4++!$;;4(25&C'8#E8'H<D4:=57)?.*D+!?40;$=-.C#F1<12261$/?:29$&%+(!5*3!1=)*>/'C='E;1%,@520?3E?.?049<+$C%("+C<+/+)4+D/!;8D51/BG#:<8E-2=?"8C$C
@r9313
AGCGTCTCATCTTTATGCGCCAGCAGGGATTTCTCCTGTGCAGACAGCTGGCGACGTTG
+
@=&'@&F:$B%9$>=6)C5:<3),G11;*0HHA!$B$D'(24A75<8:-1D8(5#D%E"
@r9314
GATGGCGTCTTCCACAGTAAACTTCTGGTTGCTGTCTGANTCCGCCTGTTCGGCCT
+
+&7CD$E;)/C'A7#:0''?;.=3BGD414F7E7E2;!%>9*2&#.68!+#0DH'*
@r9315
GGCGGAACGGTGGTCCGGCGTAAGGTTTACGCCCGTTTTCTGGATGCGGTGAACTTCGTCAACGGAAACAGTTACGCCGATCCGGAGCAGGAGGTGATCAGCCGCTGGCGCATTGAGCAGTGCAGCGAACTGAGCGCGGTGAGTGCCTCCTTTGTACTGTCCACGCCGACGGAAACGGATGGCGCTGTTTTTCCGGGACGTATCATGCTGGCCAACACCTGCACCTCGACCTATCGCGGTG
+
HA/-4&>>GD)/5/6C82.;7+E&$=";&18$;?G'/<9?$D2%?%(H.!0$!B1%%91:9$('.119CGE.#*C+..D:<C8$1=24.?G,+/F.EC&>;%7E$348D2(15>HH"%(?*@#'">)D,'C5;($%23B09>2-!9$0>>7;,=)E?4#H&#=#7&(CA&3EC*'-,'/H$<86?.1@F6=%4>//$&0A31/7#*3&D)5E="/F(+06(>""$80H/,$@+C)!#@'+2
@r9316
CAGCGTCGGCAGCTTCAGCTCCCATACGCTGTATTCAGCAACACCGTCAGGAACACGGCTTACTTTTACCTTCACGCCGTCGGTGACGGACTGAACCTCCACGCTGACCGGATTGCCACTTCCGTCAACCAGGCTT
+
=28B'("G,*,9E-C"E-5"%(8(-6&:>#@D0A/G7A0+;$?H.30B?C0?>:&B<#C%'3%,@C#-:!(/H>D/0"<A'19)3/$72$*2->8&88G/8$2-7*.?%":'-/#B4==D'#,#9??04B'*$/>(
@r9317
GTNTTGCTGGTTTCTTTCCCGTTCATCCAGCAGTTCCAGCACAATCGATGGTGTTACCAATTCATGGAAAAGGTCTGCGTCAAATCCCCAGTCGTCATGCATTGCCTGCTCTGCCGCTTCACGCAGTGCCTGAGAGTTAATTTCGCTCACTTCGAACCTCT
+
%%!"(+)$*))#"'%&*"($'(*+%!&!#$!*$&!"!*#'&"#'%+#!+&&$+*"!$)&'&'*''+!$(+#*"!&(##%(&(%%)((+#)$!&&*'$"&&((**#('+*!%&&*'%($%+!!*()'!#**)++$*!%)!$&()!%'&$)(%$&&)!'"%**
@r9318
TAAATAGATACAACTCACTAAACATAGCAATTCAGATCTNTCACCTACCAAACAATGCCCCCCTGCA
+
B<<E<(,5"E15-F#:A@.<1@2G+(C3!E,#:0;?40,:HH!"=1*?A?$D32+8,)#61>C0#/B
@r9319
TGACTATCAAGGCCGCCTGAGTGCGGTTTTACNGCATACCAATAACGCTTCACTCGAGGCG
+
/8.BD$6816,9-)7H.,D0B8>E>&8)/=#(*1>/%79,:,F#C,1"<++G665F"B!-C
@r9320
CANGTCNTANCNCNTNGAACCAAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCNCCTTACGCTAATGCTCTGTTAC
+
'$(#(&"((#&%%$*#*"(%'!&!'&++#%"'*%(*%#$(#&*#+()+*+!#&%$##*$(%*((+)#$'%!$+*'$)!#&'*''!""!##")**)$$*+!&&(+&$#'!*%)#!$$'%*%#(+!&$(!!)"""
@r9321
CACCGTTCATCAGTACTTTCAGATAACACATCGAATACGTTGTCCTGCAGCTGACAGTACGCTTACTTCCGCGAACGACGTCAGCGGAAGCACCACTATCTGGCGATCAAAAGGATGGTCATCGGTCACGGTGACAGTACGGGTACCTGACGGCCAGTCCACACTGCTTTCACGCTGGCGCGGAAAAGCCGCGCTCGCCGCCTTTACAATGTC
+
HF567GG-0#!9%=#H1H;=F63<(-5:%C'512"(+H!),A)2A1B,1=B<902=')*'1#(:C@089:9@+><H.G4!%B!9&-.+D.FBAF:?+2)7&56<C8%-?*D&8@6562='F/41.F0"1)B%*"1,;*0DGH!:3&7*C8'CH,#7#F2A(1>!@@#:6HE852)"75-D3+HC1$?D9-?1,G,1F8',5C>E)E(53$C<;
@r9322
AAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGA
+
B./)'%D8862).#G>61%0(*:.(>%A'6>0*7/7!G=F
@r9323
TCCNTTATTCTCCTGAAGATAATAATCGCCAAATAAACCAATACTCAGCTTTACAATATACTACTAACCGCAGAACGTTATTT
+
,*#AG,,&./43B?D69<8.DH&H@<CC02=$1C6F7@@#&AA!(@D%!+.,2#,7-!AB:='209='26!50)C&4=$CF+"
@r9324
TACGTTGATTATTGATTTCTACCATCTTCTACTCCGGCTTTTTTAGCA
+
+'H9?A2.F:'(44#A3!!F=5;.#"-!7(&4216.'+56E3?6-'"-
@r9325
TGTGGGACGTCCGTCGATGGCAGAAGATCGCAGCACGGTAACAGCGGCAACCGGCATGACCGTGACGCCTGCCAGCACCTCGGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGC
+
84%#0$#*D>"3=!A"G:36G/2%.30;6H'"-/)1BHH-/#%:98$(D312(*7.%73-E$/:/?G;"9B#3""#!HC37'324(5&;;1>#5B3)-2FD8)8H5@BB%#%H@5"><&B""B3F.30D3#D,
@r9326
GGCAGATATAGCCTGGTGATTCAGGCGGCGCATNTTTATTGC
+
+#"$""*!$#&*!#$)!)"%)()$"(!$%&+'"'&(+*$!#!
@r9327
ANGNNTCATTTTTCTGGTACGGAAAGTGATGCGAAAAANACAGC
+
$#'!%"*%#+'(#****#!&())&+'*(("&'%'#(!"&&*&")
@r9328
GTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGACAACATTTTGAATGCGGTCACACGTTAGCAGCATGANTGCCACGGATGGCAACATATTAACGGCATGATATTGAC
+
GA.1B5AE.)!,A=.!/)C/H9A@9+E@65C"9-62?5GB;4E."%7F42'/')4C'02,GF#2;GD.6+G8G+=B(G@6C)FC!#D%<=(6@2?-")?,G,F(@;&/2(
@r9329
CCATGCGCTTGATCTTCATCTAGCGGTTAAAATATTNCTTCAAATCTTTCTGTATGAAGATTTGAGCTCGTTGGCNTTACATACATCTGNCGGTTGTATTTCCCTCCAGAATGCCAGCAGGACCGCACTTTGTTACGCAACCAATACTATTAAGTGAAAACATTCCTAATATTTGACATAAATCATCAACAAAACACAAGGAGGTCA
+
B*&'@=28!"3B!'&;5*C2?&4B+"=5@293.;;;+)<1.8$E/3E7)81=8361"66@+17)#,A#AE;70:*:))%&1=E=-G%,9+A)%H59),#EC?36H#:(5F#B*.#4*,(0A6=<E!4/#.$BBG2C*$1#4D78#24H46E3%(7+!7=A0$B%+84?B7%7E8!"6&96E3)1+9';+745!(1,$H&E*,*&33+
@r9330
CGCGNCTCATAAGGCGGCGTCCACANAAAGGATTTCCNGCCCC
+
"'&!!(%')+')#$&*'$#*$&#)++%+'*"$*()'*!"#'#"
@r9331
GAAATCCACGGTCTGNGTTTCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTA
+
.C'&<=2;"$/C670!6?65'!02.=64+<#F!/"D))+(.)E/%4C*:-*<+*&6H1;215<+>$9;/<98<-D$/G,)-A?C!.2,>2"FE5E"A@;<CH$9C)(:EC&G1'/#?
@r9332
GGGAGATCAAGACTTACGGCTGACGAATACCTGAAAATTTATTAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAAATGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTATGCGANATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAA
+
$,=,04.F-A2D%<5!G')*F7@4C!3A)#+40>(EC/-</>G453FC>F7G<AB28FEB#68@%+4>!H2+-E>6%,B7G4*/D:E1GE>D7=::%?=6<;>9#"C<9@E79EH&-D,<BA$H*;'?5/H#!0?=>0..(&AH2(-B$9&B*?#.A$-7>5B'3D#=34&;!
@r9333
TTCTTCTTTTTGACCTANAAAACCAATTTTAACATTTGCGATATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACCATCTGCTCGTAGGAATGCCTTATTTTTT
+
F"/)1)201;BD(/<E,A:D-&FB.&C!D"GH7$;<+34F%/.%5'<+?6D642?D90";-%4%5#0'*/G%863E8DB5?4C%$E)5<='6)'+$B8%#A1;#'54<=B=@,;E;2''F;'-6H5#AD#!%2C#'</8;*C
@r9334
TCTGTTCCACGAATCAGCGGTAAAGGTTGACTTAAATCGACCAGTAACAGGTGGCCTTTTGA
+
;*C@D$AC(%AG1;>4<0%B'H,1?0*#2#:(7G$CH?&<8GA1/.:04"@D,&>*B:(601
@r9335
TGNATGATGATGCGACGGCGGCGGTAAGCCGGGTCCGCCAGATTCTGCGNATCTTCATCNGGCAGGCGACGCAGGGTCATCTGCNGATTCACTTCATGCTTCGGCTTGAC
+
('(&+-<)4+>-AH$2)(%43%66?9($/DH*;<B!6&H!(8#82*H<GGE!#3-:/"5$=:<-=":%9%D:':;.:,!G!*3$+6%E(>820DHG!HD#CBE3-!;BD@
@r9336
GTTTCCTGCTCCGGCTGACCGTAACAGCGGACGACGGCAGTGAGCGGCTGGTCAGCACGGCCCGGACGACGGAAA
+
<7"7$5&D22-BE2B1&A'4@%EG8##@*3%)&+*262!GCF680A<D:DC-9%%,&%"+!)!:56&(21A#=G<
@r9337
TTAATTCTCGCAGTCATATGGACAAGCTCATCTGCGGCCTCACGGCGTAATTCCGCATCAGTAAGCGCATTGGCCCGCATGT
+
1B!/C0$H%A=$<G+F>G"F6*&#?3H=1C<:'@@$7A5?05>C!D8>&,)'2:"428E9<?F/,5'<:*8+@7G+$6F?>C
@r9338
TGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCC
+
$36=H3>+@.1(+.'A2!A59)B&A/1#&9)H"(4"!%@HA<.+<A(*AH?"?:,%#HD!EEH0C*+E($!9G3=D))>#$580H8-:A&B)/BCC14E0H=8B#==/B
@r9339
ANNCNNAACGGCGTCTCTTTGNCGCCAAATTTAAGATACTGCTCCTCCCGGCAANGCGGGCAGGCAACATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGGTGCCTCTCACTTTTGGCGTGGAGCCACGGATG
+
"!*%!%+#+)%*$'*%%&(&('(!()*!!+'%%#"!*!*'#&+(+!#*+)(+%+)$!!+%$##")%*$#'%&'+&&+#%&"*"%%*)!#%)!)%##$)&$+$**"++(&)&'"*%!+%$**)!#(+%+$&$"$&'$)%$"#%$%"(!*'$&)%
@r9340
GCTGAGCACATCCCACGCCTTACGCTGTGTGGTCTGGTACGCATTACAGGTGATGCGCGGCTCCGTGCCGCCAAAGNCGTCCGGCACTGACTGGTCGCAGTACTGGCCG
+
;4,A'E6#-7F=+F7%=?&4'-<C2D+2B":</A51!!%0"H?DC&.,B+3G*?/:1':@+);%BB)H50%+D>E,!"C*-69B?<+*%6%"C30E)-=59-C0G!(&?
@r9341
GGTTCNTTTGATNACCNAGCNAGCGGAGACGGGCAATCAGTTCATCTTTCGTNATGGACTCCTCCACAGAGAAACAATGGCCCCGAAGGGCCATGATTACGCCAGTTNTACGGACACGAA
+
$)*)&'!')$!'"'%"!'')"+"#!(*+&*%*%#+#!&'#'('&#!'#''&!(#(%&"(*#++$(*"'!+**"'#*("++#"%*+)%*$!!')*&#+*(+"&%$%!"&*!"!!%$((%$&
@r9342
ATCAAAAACAGCGGGGCGACCATCAAAAAACGTCGCCCCGGTGTCATGCTTCTCCAGTGCATCCAGTACGGCTGCACGGAGTT
+
>@;:,+&3(-B-8E@FA9)/G13/#B<0,.:%>>:1#0&"/3'G*/?+%+1;0>!.)4:#B):B'0*9B=7F-74?@3:%*>#
@r9343
NTATGCCGGACAGGGCGTGCGCGTTGAAGGCTCCAGCCCGTCCCNGTTTGTCCGGACTGA
+
#+"!*"*$*(%%&+$*#!&!"'#$('$$&+*+(++*('+)'*)!'$**!$!!((+#$%&)
@r9344
GATGTGCAGGTTATGGTGATTAAGAAACAGGCGCTGGGCA
+
+"'$*&#(*'"((%!'&)('*!***!!+++!(*##&*+!!
@r9345
TATTGCANCGCCAGATATTCCGGCTGGCTTTGTGGCTGTTTTCAACAGTGATGAGGCA
+
,!6#A.6@0<6%F$$B':.&('4),5$&(6*F:-'!6'-<.2&80+>/'2/098@'2@
@r9346
CTTGAATAGCCGACGCCTTTGCATCTTCCGCACTCTTTCTCGACAACTCTCCCCCACAGCTCTGTTTTGGCAATA
+
6?:!&*G#1G945(=:3A$5'&5@3HD4<%1H-%3!>C9+0!4*%9DF1!D)!,@,$F4"/E62@74#7<*@6:-
@r9347
GACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAGTGGCTGAAACAGTTGTTGATTGAGTCTCTTTGGTNATTCGCCATCCTGAGAGAC
+
3*:?D?:651=1E7'&@F%+F)=<..D/1+A&F?.+$;=E3@C4C239A7H7<:2C8H!+/9:9+/(B+,<DA68G&8+4"(/(%5G))8=;*82/.C171@809>7G(86$2*B">(.&,H@F;F;-6&F3457,'2'=2;%+'-8-
@r9348
CACGCATCATNCCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAANGTCCGGGGTCACGC
+
0;7)-1B,??H!G,(A'8:E.#:E7.>C$,'A('+FDCE:3;('5@79?=%2-(;;0&822G93;9'0GH!"%
@r9349
GNGAGCGTCATGNGGNCNCACTTCTGCTATTTCGCAGGTCTTTGAGTTTCTGTTNGTACTCTGCCTTGATCGCCTTGCACTCTTCGATAGTCCAGCGATGGCGGTTAT
+
)$%'&))&''$'(!$#($&((*'*(+"$('+")#!+)*()!'$(#)'+*)!)+%"''#%&#"!$+("''+$)(%''""($!%!("''&!'&%('#%'&!(#'#$*)&"
@r9350
CTTGTTCAGAGGCGCTGAGAGATGGCCTTTTTCTGATAGATAATGTTCTGTTAAAATATCTCCGGCCTCATCTTTTGCCCGCAGGCTAATGTCTGAAAATTGAGGTGACGGG
+
+@/'=#!;1-7%6'&*5"=<$3=614!.G0*CD07;1%A-E1A+.:F>=2<'7?F5(D:/#CA:D1)3H/56+BA0$&0:59B4%:?91F59==@*:$'3F,<H2E%,G3*G
@r9351
TTCAAACATTAATTTTTTATGATAAACCATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGA
+
F$%/7+50H75A+1?6$86"A%13"$*?.)994;<2&@356"=%FA68:(;G@E6?(&EH*'09H*.*;2(E0@.!
@r9352
CGCCATCCCGGTGACCATACCGTACAGGTTAGAAACCGTCAGCGTGGGGCGCGTA
+
B;D+A+2*++-<.)+G6B)C#.'E3%/?H9/(;9!7%0&*'7@63<$.!4=#.F.
@r9353
ATTCCGCCGTATACGTTTGCCATCGATGTGCAGGTTATGGTGATT
+
F6%;'',/9"&+H/BH'B9)@<?6H:B5=#3%<1)&&?+<9HG87
@r9354
AAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTCCGGATTTGCTGCCAATGTGCCAATCGCGGGGGGTTTTCGTTCAGGACTACAACTGCCACACACCACCAAAGCTAACTGACAGGAGAATCCAGATGGATGCACAAACACGCAGCCGCGAACGTCGCGCAGAGAAACAGGCTCAATGGAAAGCAGCAAATCCCCTGTTGNTTGGGGTAAGCGCAAAACCAGTTAACCGCCCTATTCTCTCGCTGA
+
<%#H<=&-90/(A6>+#9E,('*A6/*8+;8%,A8)-AA-1?9.+E#(#C(('H?*!/B$33&5;1G7!G.91+7:*#)$F#2B0.F*HG5*6DF-AHAGD5&7"%99'!&6&&%'!B#<%E8ED;A$B79#$8+?"!)(4-7D':)<@50>:/B*>8F%4E1$&,3!;%5,E*19<72E>'>9&A+EGA)7++A&H-<(0-(%!?(:9.D!!.<0+/).1"%$*!/$D9AA8/"G374/DH335E5=6*/7!"961,";C5E7?+8A#@2
@r9355
TTNTNGNANCANNNANCNNCNACATCNTNNNNTNGNANTNCTNNANCCNAGTNGACNNCNGCNG
+
"$"#"$!$!#""!#$"##!!#!$$#"$"!!""##!!""$$$""!!$$""!$"$$!$$$$#"!"#
@r9356
ACAGTAGGGAAACTGCGTGTTGAGCTTGAAACAGCNAAATCAAAACTCAACGAGCAGCGTGAGTATTACGAAGGTGTTATCCCGGATGGGAGTAAGCNTATTGCTAAACTGGAAAGCAACGAAGTCCGTGAAGACGGAAACCAGTTTCTTGTTGTTCGCCATCCTGGGAAGACTCCTGTTATCA
+
/#,1,H-.9?/1:1@<*43'?;'2+!!A)7#&672C%/@33A#B:%&#8".?-;(2"&8+5841=.D2E!A9:;H<,?+=,6B43+,%88'33*#.D9!3@2&0#A);E,-:FD/:,<11$2F-4&2-A(=0&2)2$/9D$7E:*)7)9=8"6(+8:2!G,H@60%(/3).(3'6A;90/2+&=
@r9357
CAACTCATTTAAGCCTGGCAATCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAANATGAAAAGCAAAATCATCNGGGAGCTACAGGNTCC
+
%#:<E;?7G"!,.<E2<="1@;<F7*G=$#4BF?"B$;1*;)?F%"-.-:?<,7"+HD880+*D.1*?.&A9AA'1D$%4*@=0C?/0?6A@H
@r9358
ATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTG
+
7;&0<*A#F)>G"$#!-4*0G%E@AH0(6673'?09@.)01&@+9G7%B(01,2G;#H2;G?E'-;%C$H
@r9359
TTCATCCCGCGTNGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGNCACGACCGTGACCAGTTNAGACGTATCCAGAATNAAGGTATCCGGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATNTGCCCGGCTGAGAGGGGTGTCCT
+
;:C'C6)6F?'/><3%G'-C!+9B$<?8&B(-:;-0>'4('4G8D!5CDC-)-)<;<G-==(<3/%/>-=.E3$G;@#H676'8A(8/,9/?A(,DF)(;F43$,82E0;"'6?5/-*00>7BF/:6G)<+#::(75/+>.C@<0,@(<,'!0$3?H@
@r9360
AGCCAAGTTAATCAGATCAACACTGAGCGATGCATTCCGAGAGGCAATAGCTG
+
G22+1?GF&03HF/C@D'C5&1/0?,=;A&0%$/#%D0E-G;(:G*)"G6<$"
@r9361
AATGCNTTCCGTGGTTGTCATACCTGGTTTCTCTCATCTCCTTNTGCTTTCGCCAC
+
7)"46=B6H2*.HD!7%;90&?AA%4.CFFG=9#<+*$.$4D%=D=%)#@/&?B8>
@r9362
TTTCGTGGCCGCGGTGGAGGCAGACGTGGCGGCTGATTGTTGTGACG
+
9.-D=-5)%DH2GC7,+$$H.A26.2)79>B"<@,*,:G(?!E6)=<
@r9363
AGCACAACCCAAACTGAGCCGTAGCCACTGTCTGTCCTGAATTCATTAGTAATAGTTACGCTGCGGCCTTTTACACATGACCTTTGTGAAAGCGGGTGGCAGGAGGTCGCGCTAACAACCTCCTGCCGTTTTGCCCGTGCATATCGGTCACGAACAAATCTGATTACTAAACACAGTAGCCTGGATTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCG
+
=?1=-=>@B(3,>+)F:#H1!">BCH385>G?D(@5+='--8;2BCA,EF/&C@$A;9-"&';4&AA2,.D&F7D;6#45*AG$/8&60%A($F%$56GD'612A;)?E6;G<E$99H(3H"%D!/?*;5&8+,*(D+?G$*.&4"8.F.3HC!7%)BH3&$/"GH"9!!,?8(5'%1$5:.B;$"B-2"?5FB'&"</"#+8G#!99D?7FD;F?C/%//B6;BFB4?H"+)+F;0:4!;)5>09391G32AA?@G34<E<F,,,,)04'AB-<23?%=)926;6<#!/<./277,
@r9364
ACNTCGGGNTTTTNAGCTAATGAAATTTAGCTACGCTTNCGAGTCTCATGCGCCTTCTCCCTGTACCTGAATCAATGTTAGGTTTCCGCAGAACACTGCGCCGGTATCGATATACATTTGGTTGGCAAACTTGAGTGGTTTCACTGCTGGCGTATGACCAANGATGAACGTG
+
!""&%#)##$)"()!')!+*%%!"%+*&#%$'&(*)($+%%%%#'!$+(+#"##$+*)#)&&'&#&"%)(*)!*'&#)%)#"&""%"!'!#(#'+&()&$(""((#++$$*$+%)*(+#("#*)&()'*'!%)($'&($&)*''"*%#%&&)*$!$(&)%&%(*!'#)'&#%
@r9365
TACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGNCGGGATATGTCAAGCCGAAGCATGAAGTGAATCCGCAGATGACCC
+
8/0*"-23!8-"CB"&D740H??-+A%+#757B)$0D6D&-C,C,"9*),58"'$>5/93?46;$&.":.%.76%"EHE6%.4$&4:!*:C<?=C"6=H26:+#$/@2.<>*
@r9366
AAGCCTGCTCAGGGTCAACGAGAATTAACATTCCGTCAGGAAAG
+
3+F*2.'$?'->E5)E;%F=?D32E>F=-0BH+"4<B3#%4.76
@r9367
GGTATTCAGCCAGCACTGTAAGGTCTATCGGATTTAGTNCGCTTTCTACGTTCGTGATTTCGGNTTGCGATTCAGCGAGAGAATAGGGCGGTTAACTGGTTTTGCGCTTACCCCAACCAACAGGGGATTTGCTGCTTTCCATTGAGCCTGTTTCTCTGCGCGACGTTCGCGGNGGCGTGTTTGTGCATCCATCTGGATTCTCCTGTCAGTTAGCTTTGGTGGTGTGTGGCAGTTGTAGTC
+
-(%<A7>2B((.,4CC.5;G1.+:E'D;&$-46=$!(E8761>901C",*';%,G2.A;3%FBHFE$"7H=069G!=B.4-<'(:H:F+B?3F8A$AD61>"<30F05.*5;08=/F+987?<(/*-%$&1E244;$?003&$1<"0A(?61/&.2H+/.2G8(/!F*E.H6BH<.%(#')<?/=E3F5H23G!!&C,D.D;*#%>4G("&370=,"EHB$.-)A'$B;+!H+&4'''.+
@r9368
GGACTATCCGTATGACTACGACTATTGATAAAAATCANTGGTGTGGACAATTCAAGCGATGC
+
?,$>-94/E8&48/56G-6@#:D<-"G/9F5&??*":B,G$/B)9?:39F"8%7H%8(AD;"
@r9369
CCCCTGTTCGACAGCTCTCACATCGATCCCGGTACGCTGCAGGATAATGTCCGGTGTCAT
+
67+%>&5;1#-*.E<<90"(5$5D/*33/,C(6$9@'=C:D>B2(%/&/2:>!#+&,60%
@r9370
GTTTTTCTGGCATCTTCATGTCTTGCCCCCCATAAGGGGATTTGC
+
>!?7$;:7B@!<&**@4;F26B8+840=4'4,6'="1:>80#A<!
@r9371
CNNNTGNCTGCNCCTGGCGANAAGNTTGCGNATCAGGAGCGCCTGAACGCGCTGGCGCAGCAGGCNGATAAATTCGCACAGCNGCAACGGGCAAAACGCAGGGCCGCCATTGATG
+
*!#!''!&&*#%"#))$*()#*$%'(#!'*$+)&#'!"&+$('#'**+#+'$!)+%*))+$%!*%##%!(%%*&!(#$#!)"#)*$(+%)#)(!*+$)*+#)*'%$#"#$#$*#)
@r9372
TCTGGTCGTTGATCTGAGTCTGGATGCGGCCAGATTTGACGAGCAGATGGCCAGAGTCAGGCGTCATTTTTCTGGTACGGAAANTGATGCGAAAAAAACAGCGGCAGTCGTTGAACANTCGCTGAGCC
+
*)+'%'&!(*)%('%$+&(%$"+'#+%+%'!(((&$'*&&!$%*!$&')''&&%!#)*+')#'(%$*!+')+$#&##&&()!#(!)&)((&$$$&!#'""&%+'%*"$'!!!&#'!$(#)'*+*)+)$
@r9373
NAACGGNNGGCTGCTGGTGCGCACCAATACNAACTGTATGCGCATGTGCACCGGCACTCACGGCTGNACCGGACAATGAGTGACTGTGGCTGCCCTGACTGTCCGTTTTCGATAAATAAGCAATACCCTGTGTGCTGGTTCCTTTA
+
!*(''%$"%*!+))"#+%'+*)#+('%%'+$*%#$*#!&&'!&#%("$*+*"!'!"&&$"!(!*#*($)&"%"$&$!%$($&!)(!"$"*#&"&$&)'&%'##&'+&!))%"'('(%"%&#("('##++&++"'%%'$!%%'%#'*
@r9374
GTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGNGAATAGCGNTTTGCTGATGTGCTGGAGATCGAATTTCAAAGG
+
.71>%666E15E5#A5#&>)$$<">"BFA&5#:F,H<1"7)8>1?:>$-GFE;;@-A;@9B0:#&&7AA)-$(%4?$3
@r9375
TGCCCGGAGAGCAGGGGCAGCAGGCGCTGCTGGCGTGGTTTAATGAAG
+
:3&4'(>E?9/<E,AA%0:-!H:!%D!<#(!&@)3/D&F$A<$G4G,?
@r9376
ANTNNNGTCGTTTCTGGAAGAGCACGGGGGCTGGAAATCCTTTCTGTGGACGCCGCCTTATGAGTGGCGGCA
+
*&("%+#($$*'#"!%&!#+'+)"'#*)"+%)%"()!#()$$#%!)(#)**)%*%**&%('*"#*&'+$&$(
@r9377
NGNNTNCTCTGGNGACNGCNGGNNTAANTCCTTNAACGCTNACTTTNAGAATTTTTGCAAGCAA
+
"*%('%%*)&&')'%$!*!(*&$"$#$!%$!')$+)%$!&$#'*%(%#+("#+!+")%!"(()!
@r9378
GCCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCNGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATGCGCCGCCACCAACAGCCCCGCNAATGGCGCTGCCGATACTCCCGACAATCCCCACCATTGCCTGCTTAAGCAGAATTTCTGTCATCATGGACAGCACGGAACGGGTGAAGCTGCGCCAGTTCTGCT
+
$22FB>D!>,&E:+B*=##1!+=H5-4<HB*H)9(B!'H/1(.43/*)7112A9<!4:;!"8GA*>.'DA.?(;1<,14<:-:>H1CH+2=<EH77"(@@:;7@%@F@GC/%1B=?'-:CB#>)F)!*CA.25:A77>E39!1)'?$GD7%+"-B509=5=:7!&31=.==3=-!E:%HF0(B2D2/;32:7;@-9//"9G@,>;5E";4=$,'1H=+</D-$57H0#0B84$;$0HD"<3A
@r9379
GTTGTGGGGAAAGTTATCGCTAGTCAGTGGCCTGAAGAGACGTTTGGCTGATCGGCAAGGTGTTCTGGTCGGCGCATAGCTGATAACAATTGAGCAAGAATCTTCATCGAATTAGGG
+
<>D5<G9F'4;05-,6FC&+@$A2+'/$F?AAG@'G8G30(@AF-G3>70&;07%69F,*C3*??>0@D/@+:=15-5F&%D0<39($'/1*!:C:$4+&F94E$$%"-D%.4B5?$
@r9380
TAGAGTCTGAGCAAAAAGATTTGGNGTTATCAATGTTGTGCAGATCC
+
6"2B&<=*:0B<?#E!"4.37A1/FG3(0-/40%/H.?2(%0A->(,
@r9381
AACTGGAAAACCGACATGTTGATTTCCNGAAACAGGATATCATCAAAGCCATGAACAAAGCCGCGCTGGATGAACTGATACCGGGGTTGCTGAGTGATTATA
+
C%1@'?:=)#@6A-*8(H5.9G/2$!,<54%2@#B/09-4<?-8D+B;38G'-.83@D#!D7'(E!%GG8=7);<>59'::B?/6;DHH(090,;C#/"H4F
@r9382
TGGGATCAGCGCAGCCGGATACCTTGATTCTGGATACGTCTGAACTGGTCA
+
)4?H,-.F:?0G2-=E?0,HA4GCF-"6%G4D86>%.?5=7F%30646)0#
@r9383
TTTCTGTCCCCCGTGAGGAGGCTACGGTACTGGAGTCGTTTCTGGAAGAGCACGGGGGNTGGAAATCCTTTC
+
0B9-6'".&134-9*1<196$1566+EF&?,D*EEE=)=8#"&?7?.E8?$H39$;&:;;H!%@+(-$H5<,
@r9384
ACGTCAGCATATTTGCTCTGGCTAATGGAGCAAAAGCGACGGGCAGGTAAAGACGTGCATTACGTTTTCATGGATACAGGTTGTGAACATCCAATGACATATCGGTTTGTCAGGGAAGTTGTGAAGTTCTGGGATATACCGCTCACCGTATT
+
3+A,<8"7?B67?$6'C3=*>;#?2E).;,&=8="7H%":15A:4%AB-+GE.=E5247*+-H!$7A:B"0-D"+'5#6G..,.E##$B>28"ED-/6,<E1&-?$>:,$<(@@D(?:C5A#28@)2:7#++>25"H;)&;"90>:&!.9$B
@r9385
CTGGGTAATNCGCGGGTTGTCCTTTCGCGCCGCAGGCGTCGTAANAAGGGGCAGCGTTC
+
+!'?2G@D.;8(#,?GG4.4C),5"01.,4+#"(),3>><@+7$:@F"1F="67DEHB7
@r9386
TGCTACACCATTGCGTGCATCGAGTNAGTCGCTTAATGTT
+
H#D,)H?30)A(E6G3;9?"<,=)&@7=2A(A"6.4!9E=
@r9387
AAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGCGCTTGAGGATGCGGACACAACGAGAAAGGGGATAGTGCAGCTCAGCAGTGNAACCAACAGCACGTCNGAAACGCTTGCTGCAACGCCAAAGGCGGTTAAGGTGGTAATGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACTGACCGGAACGCCAACAGCACCAACCGCGCTCAGGGGAACAAACAATACCCAGATTGCGAACAC
+
<?9/+$(216)EC4G8%G?(8"*.5/G//0(H'"D-$>'1<;B1@B9$/#(A"<&E!:DF.F"4"174H;/$;1ED67(6F'&=;D&0<*3E:>#:0,BC(=H"/7-)42H?@4<$6/&4:D$G2-04!.0'4:>B?';&73($BDE<&>:B#G!3!((59?$*#/#)::&(<@@C&8FE+E,G(2-=A)"D@/?.G03F/.0B*:DH;A.18/7+.;$,##F">#@$2))#;E29.7+58%*@/",.-C%@H8HE
@r9388
NTGTGGGTAGTTGGCGATCTGCACGGATGCTANACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGTGGTGCAGAGAACGTTGAATGCCTGGAATTAATCACATTCCCCTGGTTCAGAGCTGTACGTGNAAACCATGAGCANATGATGATTGATNGCTTATCAGAGCGTGGAAACGTTAATCACTGGCTGCTTAATGGCGGTGGCTGGTTCTTTAATCTCGATTACGACAAAGAAATTCTGG
+
)*#.(D61.4(FB4'FGGBG45:@"@+C26(89>5?'"5?4:B67G<(>FA-E>?B&2#("A=?>+9H2A13D%;.03>D<>/D>!@C!1#.1C')E$4'4C0#4"*E?"368FE(D,),21B./DE)2?462H&5HB21"CD/&-+F7><44=B*<?02<9A,(4G=>:#9D.?G0"G!?C?+A=$+A)>'"/C5E7($!2><6;F2D#C&":%;#$&E94"97A$C=>6D3'G2$+>#*&.*(E-1:6?>5(+9.??9B%'"*29(9;,E(!<6#"H$'%E'779&;+%&
@r9389
ACATGGTTCTCTCCAGAGGTTCATTACTGAACACTCGTCCGAGAATAACGAGTGGATCCATTTCTATACTCATCAAACTGTAGGGGTTGTAATAGTTTATCCGATTTCTCGCTGTAGGGGNACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATAT
+
=9>AE*79"9(,1(,,%CBB1>$-8G73?1/)$A/;394?7!D7HE>A*C)<5F"D'3>/4??HC//EA)"0!?$$?BH'4)E"G66>F>%)%.7+2%G:F9B*2"#=$428;8-#E0B;"/0(GB(.-@?'5:2/<(!6-B.:&D*'39:B+"1FD<E4317H60<.4B7;-6<?#ED&9429<=,:C5!0#@5;C(&(?5
@r9390
NGTNTANNTCAGCCACACGCTGCATGACATGCCACCGGCCATTTTTCAGNTGCTGAATAAACGCGCCGGGAATACGACGGTTACCCACCACAAGCA
+
'%$!*!)%+$!%$!&"!'!%*&"+&#*+()%!"**'+%"*++!(%'))'(#($%&%(*+)'('!*+$(#"!"#*%$#+))'%$%)%#*!+$(%)&)
@r9391
NCCTTTCTGTTATCCGAAATCCACTGAAAGCACAGCGGCTGGCTGAG
+
#>%4'3'G-6)6+&B1/'8>0((:/898/.3D=)+F6F.8AB7,6E(
@r9392
ATCATTGGGATTCCCATCTTTTTTCTTTGTTGAAGGCGACACCATTGGTTTTGC
+
F%-9:B!2B4GFA0'<>&A%+5)4(,.='D@G9A4-<4E;A/9(9:B95E8/D7
@r9393
TTTNCTGTGTAACTAATTTACTATATGGTTTNTGATAAGAATCATTGCAAAGATCAAANAACTTGTATTACATTGACAGTTAAGCAGGTAATTTTATCACCTCTAAAATATATCAGCATCTAGCA
+
7+7>0DD"F?7<%+D7)6C&893):-'"7.'=$@4+-*)<*H49C%.#;@(,&63D2&!)0;C<0A'$=C*/"H$083F6@'<13<)!D3$.+G8:A<D.(4D#/:B-%B(6EEC'04(@>C!''
@r9394
CGNANTGANATAANTCAGATCGGCTGAACTCCACAAGCCCGCNTCATCGTNGCGCCGGTAGTCATANCCGCTGGCGACCATACTGGTGATCAAATCTGACAGTGCCGGGATNTCGCTCATCACCGGATAAATCCGGGACTCCATCCN
+
%&#*"%'*"+(*!#+%(*"$%))$$("'&"#!)"*+$("%'*%"+(&)'$+#*$&$%$(!'%)!+++'%#$')*!$!&'!&++&""$*+)%*+!()#((!(&$'!%+$+($+%*"+*)'$!&!!"+)*&#)'!+(("))&$"+"*$)
@r9395
GTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAACCTGTCGCACTCCAGAGAAGCACAAAGCCTCGCAATCCAGTGCAAAGCTTTGTGTGCCACCCACTACGACCTGCATAACCAGTAAGAAGATAGCAGTGATGTCAAACGACGCGGCTGACTTCTTTTCTTTCACGA
+
(4BF06:6/?H(=7?*&G:EBBH4.737A&6ABB:&">"?)."3;$-6*#)'G5CF7E2H,BA@C=@8"'-C&0#F94>=ED90A>2E>8$EA0CF+8%?;7G(!#2(3/:E0A2=>7D*C8,9==3H4=9&++"F'2>1#%<C1>B<$$?H((64';3.@AE>F#79A.70G>;0H%<5:&5@.;/*C7521G@==3%A?7
@r9396
AGAGNAAATCATTCAGCGTCCCCGGTTGTGGATCTTCATACACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGATGACACTGTACTGACCGTACTCCACATCCATGCTGTAACGTCCGGCTTCATCCGGATTCTCTGAGCCCACCGTGTTCATCACCACCGTGGTGCTGTTACGTCTGGCTTTCAGCTGAATGGTGCAGTTCTGTACCGGTTTTCCTGTGCCGTCTNTCAGGACTCCTGAAATCTTTACTGCCATATTCACCCCACAAAAAAGCCCACCGGTTCCGGCGGGCTGTCATAACACTGTGTTACCTGGCTAATCAGAATTTATAACCGACCCCAACGATGAATCCGTCAGTACGC
+
#'2;/F;/<D+$:B+9D)E-=BG'>,<C/5D3'8&G<#4FB#6):8&=%+>+E808?:9;.>,+71B%'$!D9:D&)18,#4"11>H%@*9)/7A'&?%;&""02*0-%.=;1B0'43)2.($3,@2)/8+4!+A9-G1A<%H))C"1H#'3/!$F">(H/E1AE'G%66/;6A$1!&F!*!B7D5'B/4/>"A,7;!7'!C&;H$2".@719-?-18/G?/#H+17%1F&E+./ADE$/7*@2?(>$4C"0<"&&'@A1)187(9/"#&6/D&*G3E>#HGB=G>(?3A'+44@.8F=2%55$F<!F##F&<@3*7%'=EH0,4,85)(E%"4FB3=?0:?!+/7:<5%#"B)AB3!+(?)./E0G88.$1A39=)8
@r9397
NTANNNCTTCACCACGGAGAAAGTCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGCTNTACGTTTCGCCGATTGNTTCCGGT
+
')%##!%)+%'+&)(&'!+(++*$&!(##+%""%''"&()%*%'*$&)*$'('"&)&#&!(*)"!$)(((**%*&+$+!+*'(#)&+$
@r9398
AAGAAAGGAGACGACAGGTGCTGAAAGCGAGGGTTTTTGGCCTCT
+
,42.05D41&)()++4%E>&<F9.=?G>%A9);505>>*2@)45A
@r9399
CNNANCTTNTTCCCGATGGAATGGAAAGCATATANTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGNTCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTT
+
)!%)!#%'!+($%%&&)#!"$#$#)+#)$(**&++!&+(%+)*'&+)+%#)$)!(&&*&$+&""%!!!#"##(+"*##(#!+!%')*)"''!#'%+#)"+')(#$"!"!%("%%&'#('+$"*"*%!"*&#)(&*#)!*"*$#!)"(''""")++$&$!#
@r9400
AGAAGGGTGGGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCNCCTGCGTCGCTGTGT
+
=)+#DG%59D"?F0B6$>9!@!"88D.2C1+,$FA#C,&)<=71+;E9?&;%<@:?."17.)A.
@r9401
TGNAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTNGAAGATATTAAGAACAGC
+
&#"&+"'$')!&"(!#++#"'#"*$)"))('&#+((!!+!'""('"(#$("!%(#(#($)!$#+"!$%&!#&(&*('#*%(%*&'!*%#+($!)
@r9402
NAGCCGAAGCCCTTCTGCGCGGACGCTGAAATCCACGGTCTGCGTTNCCAGCAGTTCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGC
+
"!)'=6!=!$9<4<.@)*@'<#%/6>2D9D=E4&0<H3$+@GC$4$$";@*@)3D8*1G/5'=#13,?0G+;,#>2B;(6$-'.((&%;"4&E9
@r9403
TTCCGTCGGCGTGGACAGTACAAAGGNGGCACTCACCGCGCT
+
F!1%%<!.E%,.!)9$/E4;!C/1G:,0BAB8+@C>!4%;<B
@r9404
NCCNAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTCACTTCCCGAATAACCCGGATATTTTTGATCTGACCGANGCGCAGCAGCTGACTGCTGAAGAGCAGGTCGAAAAATGGGTGGATGGCAGGAAAAAA
+
#EG7+-!D%372"#E>#-)$5+>@5>;EF*!?',()!..'@4+2F6.%8$H3G-7-5D.-B=H=/?07#)=&E!-F?&?@/7A/=+A3E;A9'37?#A?:5,E;=31G4C=G%=0E9&,?%0<-2$6-9E:'?3H4A5'!9=&:!+E+%?G);&/5;>#>84!$B6+&$HEA)CB>/,7'&B4@#
@r9405
AGTGCCGGTGCACATGCGCATACAGTTGGTATTGGTGCGCACCAGCATCCGGTTGT
+
7DG(F=>&&>!&0EH4,<%0'@=!?#1F34GH<9:--C1(&'D8:?-8*C8E>6,%
@r9406
TCATTACTCACTTCCCCACTTTTTTGCAGAAAGAACAACAATATAGAATATTAAGCTCGACAGGTCAGTTATTNNCCTACGACAGGACACACCCTCTTGAGCCTACAACCTTAGTAGTTGGTAACCTGACAAAGGTTAAATTAGAAAAGCGTTATGA
+
8=*1CH:1<6')+H.6'#2B;5<>0?$G%+.C>8",,!2&#;7G#:196ECC(C3D1-.D,9'D1$"0GB2+F/?CB53'?@D$BF2>E@<G/H#3&0F"5">'B51,1>"$E9DD.,A49*B:((E!A#/;".A:@:#G;8'4+F0,;)$<18'E0
@r9407
TTGCTGAACACACCAGTGTAAGGGATGTTTATGACGAGCAAAGAAACCTTTACCCATTACTAGCCGCAGGGCAACAGTGACC
+
6?/9<4(-:DF&7E>C5>36)9"2$%8<(#>/?G'5%/B(F<G=B;C7BG26?27C2%>3E7A1.&<-;+C(;*G#>#F588
@r9408
AGTTTACCAGCCAGCCGCAGCACGTTCCTGCATACGACGTGTCTGCGGCTCTACCATATCTCCTATGAGCAACGTGTTAGCAGAGCCAAGCCACAACTCTAATTTTAAT
+
)())!+%&$$#))$%)'+#$)&!$'&+'$*+!&(#)(&()&%%'(#("&&*"*&!!("+!#*&("!&#$#)&%'(")%)&#)$))+($(*"''*')"%%&$+!'$%!+$
@r9409
NGNGNNNGTTTCCAGCAGATCTGTTTTAATCAGCCACAGCCCGGCGCGGTGTGCCTGCCCCCGGCTGGTACAGCCAAAGGCATCCATCTTCGTAACATTACGACCGTAACGGGCAATGGCCTGCATATCTTNAACAAGCTCTGTCGCCGTCTCCCAGCCGTT
+
!*!#("*''+")%%"'(+!%!)$$)!$"!!*+*)+&%&"%&**"$*""#!#+#)')$#!)*'!)%*##&+)!$)++)%!()""'###&*)*&&!#(%()!+!+(+)'!)!)'"*&""'#!%+!*'&%&)#++(((+*!%)$')")!$'&#*$"((*!#**"(
@r9410
NGGTNNGNCNNNCAGNAACGGGCGCNGNTGCAATGGCATATTGCATGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTANGCGGTAAAACCGCACTCAGGCGGCCTTGATAGTCATATAATCTGAATCAAATATTCCTGATGTATCGATATCGGTAATTCTTATT
+
"()!$$&#'*&!(*$!&$'(&%'&(!#$&+%*!)#*)!*&'!!++))"+#*#()(!$$"(!#(+&&*&&&!)#+$%!&&")#""$!#)*)#+#*(#*)"((!$&!)(&"%*$**(+'$!#(&#$#*#!")*(+*(+''(#%#)$)"%"#!$%%)'$%!!)!&!!"(#++"(&+%*&$""++&"$!*++
@r9411
NACCCCATTGATGTGGTGAAAATCCCGATGGCGGTGCCGCTGTACCACGGCGTTTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCCAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGAGAAGCATGACACCGG
+
%279G9)8B*>*D@16?0H*H7+-.7GE"$+'D3@G$8)?#A/CHAFC)5F>-:A'1+EC7-GH3CFE&B29F+D::DFE25E(/0!A.1'%+$"!)H@?G>A!*D9%&,@06-9#D<%A5))',15<".H4G8=!+&@@;'HG9//D)41G=H1=<:00.25+E'(B6-<79-4/7+;110@H4!A&,"7'(*!8(83)-==
@r9412
CACCAACCGCGCTCAGGGGAACAAACANTACCCAGATTGCGAACACCGCTTTTGTACTGGG
+
F-5,?!B>36"B2-!:/FCD$1?87A>$5.-;B)%"D<G+B%'A5!B)/=4H)5#C"9,+*
@r9413
AAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATGCTCTGCGTGATGATGTTGCCGCTGGTCGTCGTCGGTTGCACATCAAAGCAGTCNGTCAGTC
+
7$A<@D3%=*7,D<79?.,7E$B</'A2(5F0D/,'%@,>.6+$-47%):D$(*D=#.":!<<!2+C#91=2C6+6?'01-+!-H#;E091(88%1-FH>,@0G"
@r9414
NNGGTGNGCTGCATNCCGGTATGGAACGGGCAGACGCTGACGTTCGTGCAGGACCGACCGTNGGATAAGACGTGGACCTATAACCGCAGTAATGTGGTGATGCCGTATGATGGCGCGCCGTTCCGCTACAGCCAATTTCAGCGCCCTGAAGGAC
+
!"(*%'*(%$(%&'$'+#(+&'+##$+#*!'))")%"$&+"##+++!&&#"%!'%*++!&("!%(')!)#'&&+%"#("&*$&'$*"(##$$(*!#'%%*)($)"')%&$'#!(%)'")+'"$""+#$&#($"&'*&)%%+)'""&%$"+'+&%
@r9415
CGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGGATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAAT
+
4G'G204'04@(&D-BGB=G!4%:@'0/-6!&;'>!&5G*+B#/."!;&8%0<&A71@&!<<=))."+G6:)4+9+H+HCA)1F2.3F*!0A*>G-?;<AF)<*7;A@@*+?FD.6",-#0,C%'%1D".
@r9416
GCATTGCTTGCAAAAATTCTCAAAGTTAGCGTTGAAGAATTTAGCCCTTCAATCGCCAGAGAAATCTACG
+
=,2(G*D)E/1/2(?<*-!3+#+F*93&';0!8/6:DA<35<!?#+-$G7F:+F>18?+*)"E=/234=>
@r9417
AATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATAAATGCTCGGAAGGTATGATGCAGA
+
988F6-B#<!7#@11?@9.*#8)?D/5E"!(8(@'2<=@92/%!;=,?!!)+>@&2.=@C0CE!E/B+17E3()
@r9418
AGTGCCGTGTTCGGGTAGCACTGTTTCACATCGATGATTTCAGTGTATGACGACCNGAGCGTTTTGNTCTGCAGCTGGTCTGTGGTGCTGTCCGGCGTCATCC
+
+D%$FEE2,:H?9+>E$A+6597-"==*93D)D7@$)E-F0$:27F3?5#@C=).3-)!<8$"59;A%(,5+C8);<!(819H0'4G>*E&<;G7@!.H.209
@r9419
NAGTNNGTNGTGAATAATGCCCCTGAACAGACAGAGGACGCCGGGCCCGCAGAGCCTGTTTCTGCGGGAAAGTGTTCGACGG
+
'*(($%%$*+"')'$"'#*("*%("(&'#&)+!$*"))'!)!$$*"!(&#"##&))))++&)(!))%%%%!!+((("%+%%+
@r9420
CGTTAACTTCCGGAGCCACACCGGTGCAAACCTCAGCAAGCAGGGTGTGGAAGTAGGACATTTNCATGTCAGGCCACTTCTTTCCGGNGCGGGGTTTTGCTATCACGTTGTGAACTTCTGAAGCGGTGATGACGCCGAGCCGTAGTTTGTGCCACGCATCATCCCCCTGTTCGACAGCTCTCACATC
+
+H724DC$7=>4C61DE!H+);A1HEDE930BDE#E#;19FGA?:(/?=1%<5$A'6AH;<(22>/'?$6G%/H"-C&4>668,+GB"00&<./CGD$<8<.<9!6>F):9!;8-:0H';)!B)C*1%(D@-%H5D"*.%HA4:&DH,B-7);=-D"$F%C,-/>C=<1&AF%+507-<=:D5;A,.
@r9421
TCACGNAGTGTANCAAGCGTGACAAGTCCACGTATGACCCGACCGACGATATCGAAGC
+
#*"''#$%(&!(&$+$$%(*$+))+!"!%%+)')"+&""*'"+)*+''"!(+**""!#
@r9422
CCNTGNNGANATANTNNTGANANNNCTTNAGTACCNGANCTATTNCGNANTCTTGACCTTTCTCTCCCATATTGCAGTCGCGGCACGATGGAACTAAATTAATAGGCATC
+
)$!&$!$*(%#&$)##%(*'"!#""")!")#**%$"!*#%*'#'%()%&"!+*(!$'$*'+!!(%$'"+"")$*$$)#(&$&()%$#&#!&##$)"!'!)"'&$%*"&$(
@r9423
GTTATCAGTTCCCTCCGACCACGCCAGCATATCGAGGAACGCCTTACGTTGATTATTNATTTCTACCATCTTCTACTCCGGCGTTTTTNGCAGCGAAGCGTTTGATAAGCGAACCAATCGAGTCAGTACCGATGTAGCCGATAAACACGCTCGTTATAT
+
5=>)6-(,D!'<C20879.A,+;&:6=3)*3#2!;.=E4%2-(8?D3=BC+(&7(+F+)F6E@8BF+!&/,'-6B*<";>!7:G.->#';6*>??8->9C':<G&4&0F%-!E<F2A'%F'G:H,"-*=0;'!%+6<2;,0<9=-<;.@722*!&22C+
@r9424
ANCGTNTGCTNNCNNGATNNNCACCGTGTNTNGANNTGGC
+
$#$"#$"##"$"!"###"$###!"#!##$!#$""!#$!!!
@r9425
TACCCAGAAATTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCAACTCATCAGTCCGGACAAACAGGGACGGGCTGGAGCCTTCAACGCGCACGCCCTGTCCGACATAGCTGATATTTTCAGGGTCATCAAAAACACCACGT
+
6H-)?%!00H<37B@888@32$)>!3(6G#C.A%$4#5&#(CCA8BB>0&;-93H9@00&>ED2*!,;=F0F?=/<F$8?3">ABE$>3?3"!195,?E$4AG,<(<<GCD&@,$E>4:(@?=6=G6<H>D(@E':&*#0@)&<D(70B5/G-3
@r9426
TCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTAAAGCTGAAAATGATNCTCTGC
+
/DA@&5%=!<387"-F#"4<(14'1*!E0:"A?)1(!%"=6B$(%8<=G$&-H6<(=),;/2.C(E.?;#:%$!2&-;,#5./D8@FE7'@;@(3%E4-:3@@)F&3"E/&!E->:1(;7)D=H:)"&4,.8#D2F7F218.-D8D=A$1>,6DE44G%:#6<-+9";B:;=C2)FFF@F,39583":409##DF8=:.:05:/8";B@"5(F#/:8>
@r9427
TAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCAGCCTGGCCCTTTCCTTTACCAGTTTCCGGCGTACCNTTGTCTCACGGGCAACCT
+
1!<,*!B(EB+8H!2B&7#4-#D;&3#<33@93&7,#43##1/HDB;C03*G*&1<;+(@4B;/FHC;AG9:C%.GBC59#,8$<A@+=;209-;#=>A
@r9428
CGAGTTTTGAATGGTTCGCGGCNGCATTCATCCATCCAATCGGTAACGCAGATCGGATNATTACGGTCCTTGCGGTAAAT
+
0-E?+7+?F2H;389./&,?,?9&,H#.FA0B>F=%/$-'(:8(!3#"0<*B661F09@-F>:98/+?$+-0-?H3,A,3
@r9429
AAACGTGATCCTGACCCTGTTCGCGCTTACGTCCACACGGCATTCGGCAGATATTCCGCCGTATACGTTTGCCAGCGATGTGCAGGNTATGGTGATTAAGAAACAGGCGCTGGGCATCAGCGTGGTCTGAGTGTGTTACAGAGGTTCGTCCGGGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAG
+
F,+!@(4#-?="1!'?1$"1-)56A=1*C487"E?+8#?E*A)F9?")F2;745.B;$4/;1?:!C14&#EC&16*$3&#90)(C?&4/&F/)@>/&':A:BC:?D,+9!=(9#C-&96<)5)HD(9.B@@"1E)>?+"*<-B&-C7%=7.&2CB$-',(<"H@+@!*497=G;:"4F:98F;#0+"?57=(/E=$'1BG9#G.'=;0!1?D!BEGCB9"?7=BB9%!F%))-;1H#%'(@>7
@r9430
TTCAAAGAAGCGGGCGGAACGGTCAGANAGATTGATGTATGAGCAGAGTCACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCATGGGCTGTTAATCATTACCGTGATAACGCCATTACCTACANAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACGCGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTTGCTGCGCTCGATGCAAAATACACGAAGGAGTTAGCTGATGCTANAGCTGAA
+
#,HG0CG6$4(),?(:-+'9*-GE9#!&%H4?=AE=%>$&%8E2"(*F87.10=,(/*E(0+B0@!4D4>BA=<4'B5,89@!$(?1%A*E;7(,+(FH30!H"48E):+20*+5F=6863*D1D).@%#.<?:<F@..43:=-:1147::.,A$65F*<&*G<7)A#&6#7<@1=66AD87@/&BG;>'2+=;&#+F-<H-6+$/;,"9/D:%:?$*0<+)-B-/(&@5($25G$7/@;+'+3?3'?>+A-,'!$HE-)3;++49CB;%3#
@r9431
GATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTGTTGAGTTAAGAACGAGTATC
+
7',G<C)?@!*3A'6@3GC"C97310C6B*#6!HDC%@/,@");(:;,)5H>)/BA8E/.01"
@r9432
ATAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGGCAAAAAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTA
+
8"D0!1G<H4DE:6C<6AC.(A4E?0F5&&GF=;'!>H$),.*($>$)<=+661=9"F:-<19$$-,/FE(,:EH>4*'C0'"/1G)>5=35;'(F8"*5E#&9&3
@r9433
TCCTGACTGTTCGCGCCCAGAATAAAATCCATCGCTGACTGCGTATCCAGCTCACTCTCAATAGT
+
'G$.D<&"5-2=<D.5>@)00B@DD<<63,)D>D?>98A<7!#!7+9#7<G+->&/6H?<8+!*E
@r9434
AGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTA
+
+-(EE+.7','F27E&1?#<.98A!%B=/!AG)G)$E315,--%8+BHH
@r9435
NGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCNATCCGTTTCCGTC
+
"3=%E7"6,0?>)A+:D&0<0.805!5G?/.,!&3*$EC/&&7@3F'H6"D5:
@r9436
TCAACGGCATTATGGCGGTCCTTCAGGGCGCTGAAATTGGCTGTAGCGGAACGGCGCGCCATC
+
.<;4)1<!2E#C&B;(#&"7:(9G+F.<5'$(58G28;=84FA"")?#0?!'+<E2@)'??:0
@r9437
ACTNTGTCCGGAAAAGCCGCGACGAACTGGTATCCCAGGTGGCCT
+
/4>92".>B>CHA$.'A96@"F6D@/<HCEGHF<"$8$;@=<'1$
@r9438
NGCGACGGGGCTGTATCAGGTGCCGTTGTCAGCGGCACAGCCGGGCGATGTGCTGCTGTGCTGTTTTGGTTCATCAGTGCCGAATCACGCCGCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTG
+
+$&*"*%#(**(%"%(+&#*!%$+&)++*#&#(!()*)%$&""'#&*!$"*)*"*$#)&""*$)&*#%%#!%&!'#('+&&++'*"%*'$'#%$(+$&)"$+*(!)&*#**+)&&%#&#$$!$$%!+&*%++!!#$)&#$(+
@r9439
CATTAAACCACGCCAGCANCNCCTGCTGCCCCTGCTCTCCGGGCATCCACG
+
:0G/3635G!)=0-4>C(*.:73.45*D81!)H=C)D!C(+#&>6A,-,$E
@r9440
CGTNGATTATTGATTTCTACCATCTTCTACTCCGGCTTGTTTAGCAGCGAAGCGTTTGATAA
+
:;>2>0626%"789.*"(,B)?8F;/FD0>>43.$(*HF3E/),;=0?93H#%+-</F847%
@r9441
ANTCCATGGCTCNCTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCCGAGAAGATGTTGAGCAAACTTATCGCTTATCTG
+
$"''%"$)&&%"$"+&$"!""$"+$''%$(**$!%'(%))$+#('*#)#&"'!%'&+*&(''+%(**%('''*(%$"+)$(%&'(#()
@r9442
GCGAAGCATTCAAAACTCGCGAAGGCAGAGAAATCNCGGG
+
(E')"D$9&+>C/0G$H2C1&G+99G-4,5:!B;#CF1<E
@r9443
NCATGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGANCGCATTCAAAATGTTGTCTGCGATTGACTCTTCTTTGTGGNATTGCACCACCAGAGCG
+
!:#)++>%-$4-/8>CA9=>9!@>6<C0-9E24#<FA05E(9D?86;+<FC(1'D25+;81#=4C!<+AH?5=%A7'@<2E?(!%$A5%F#EH(A!'=)"5$77)F.$AG
@r9444
AANCCTTTGTCAGGTTACCAACTACTAAGGTTGTAGGCTCAAGAGGGTGTGT
+
#*!'(%'+)*%**$)')')##"*'**#&#(')")(%!(!'$"*'+!'+&'*!
@r9445
AGGAGGNGAANAGNGACAGCAGAGCTGCGTAATCTCCCGCATATTGCCAGCATGGCNT
+
'&)$%*"*%)!')+$'$)#%"+&"*"((')!$+$!!(")"!("*$"'''"+')+&)''
@r9446
TCGGNGACNCCATCCACGCATCCAGCTCTGAATCCGGCACCTGAGCAGGCAGGAAAACTTCGATATGCAGCTC
+
&)$*'(%&"+#!'(*&*!!$()'*)%)(")&'!#++#*'%+%*!&!(!("$("")"!%!&'$+!)*%*("*!#
@r9447
ANNTTTTNANNTTNACNNNTNTGCNNNNNATCGNGGNNNCCT
+
##!$!#$!#!""#!$"$!#$!$#!!$!$"#!""""""#!$!"
@r9448
GCAATTTGCACACAAGGTATCGGGGAAATACCGTGGCGTGGCAAAGCTTGAAGGAAATACTAAGGCAA
+
D=2.0?A#&A>*&".>8FF6='&=4>(-&5,><CD67293(:8)G:*G3204G@;$.,6F$<;++?C2
@r9449
GTGAATATTATCTGTGGCTAGATAGTAAATATAATGTGAGACGTTGTGACGTTTTAGTTCAGAATAAAACAATTCACAGTCTAAATCTTTTCGCACTTGATCGAATACTTCTTTAAAAATGGCAACCTGAGCCATTGGTAAAACCTTCCATGTGATACGAGGGCGCGTAGTTTGCATTATCGTTTTTATCGTTTCAATCTGGTCTGACCTCCTTGT
+
/C?G&3EC058B3!4%&!#;3D8D++!<(!("':9%2#*05,69+9@-1?2;H=6++@7#"'HC,.C,!;;"(+$7FE22E51C8AD"C7G!?<C;7(.2$7.3@G$8,)D,C($0%!<+78G;5<>5!H@?)(->&E3?;8.</4/*F1)+19&6>05+>5C(E$E)0=-DB0%0==,'E#E07B5'%<0H;/F-7F75;#+?C3C;F&?!%".'
@r9450
ACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACC
+
HD:8?60B&?733D#HHD848+2)"H5:8+'$)="7&H*'+2F5<+D(2
@r9451
GGTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGGCCATTGCCCGTTACGGTCGTAATGTTACGAAGATGGATGCCTTTGGCT
+
),D$>3A8A:803/0>-@?H6)D"!E@.3?E#3*=;5+)'D&2'<@*#8'?1?,GC8.(+3C!DF->'8!(2;@?D$+/<E>),3C2,%(3E.CC#/8G$70FH&*/>(.#@EC'
@r9452
TCAGGAAATTTTTGCCCAGCAGGTCCGTGAAACGATGGAGCGCCGTGCAGCCGGTCTTAAAC
+
((BHBHA5&"?4%0)-?6-9.+1.A4?5E6"9;>C900<:(%H$4E@(570&7&F)+A3/7G
@r9453
CGCCCTGAAGGACCGCCATAATGCCGTTGAGCTGAACTGGATTGACCCTCGAACAACGGCTGGGAGACGGCGACAGAGCTTGTTGAAGATACGCAGG
+
CH*9BF38AB<4-,/(6?"8G)GB8#-2%$?4)-4(+D(9>)@0&.("#!@++%H(H8$H18B!(!9;:CC%9C%D0HE7'F*H6-DH.$@/?-(-7
@r9454
AGTATCGAGATGGCACATAGCCTTGCTCAAATTGGAATCAGGTTTGTGCCAATACCAGTAGAAACAGACGAAGAATT
+
':->1>5*-,(21B4"9?8-9:?8=*)311?3838,'1+215394/(FA*<)4)CC8)0?A7@C6&$C>2A-B$53+
@r9455
TGCCGTTAATATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACCGCATTCAAAATGTTGTCTGCGATTNACTCTTCTTTGTGGCATTGCACCACCAGAGCGTCATACAGCGGCTTAACAGTNCGTGAACAGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCG
+
8<+HH/.1@74#BBB!:'?6$*218$"C5E"G&#1'F@;E'?ED&83("73-A."=:8&?6D?"<,'FF&9B793#8<(BE5$/2842(.E='7A@'3A6,A=;FD'>?*F:>C07CD'A91@F6:<?-DHCG>.*$0-6"A@1$;+=!7%%B$1C;@'B+.=='A<9F&G;G/42E0G-C6'&#.77FB2
@r9456
TGGAAAGATTTGTGTAGTGTTCTGAATGCTCTTAGTAATGAATTATCAAAGCTATAGTAATATCTTTTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAGCAAGATTTTCCCTGTATTGCTGAAATGTGATTNCTCTTGATTTCAACCTATCATAGGACGTTTCTATAAGATGCGTNTTTCTT
+
F"F-#<<2D88(BF?*?$1"@#A<2BB!C&"-?57(("A-D()"C74C".0<7F?!D.D$C3('*2?7&2!<=;D#('*37.C0:C*;%*F6F55780&!;5')?-?B.9@A;A3)C69#6FH<@E)EC@1./;8'9@?/2%C!*0"2-6+80(FE,A.65BB;',&=$'<F'GC.2<7>'E:F#C.C@(7&B>C
@r9457
ATGTTGCCAGCACTTGCAGTACCTTTGCCTTAGTATTTCCT
+
63@B+HE>FE5D+$E"(&HH",7@4A)?,+7&)?0,1@C:1
@r9458
TTCCGTGTCAGCACCGGGGCGTTGGCATAATGCAATACGTGTACGCGCTAAACCCTNTGTGCATCGNTTTAATTATTCCCGGACACTCCCGCAGAGAAGTTCC
+
1@E5,)*D$FC=4+A)10(H*6@'F..<-$<67>"*"&>+3@(C-E$::HGD?=2:6D=%=G/CHG18=<++9BC('F<"=B/!($"(3D?>?>/8;+E=$30
@r9459
GCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGGAACGGGNAGACGCTGACGTTCGTGCAGGACCGACCGTCGGATAAGACGT
+
B!53&G3@$+.(@@)">51G?!-*B)FB"9G7)#D.06=6E@#4%<!'8$B"6.!DD-:.A+:2A4D/B,/=8;7+4H;C%#$B0B6*G66@/17)=-E9:9'?#H)?.$H%E"B<4.B%4B3&!,%)&6E%-/AA.(9($D1;":>F<5#7HC-7
@r9460
GAACTGGCAGGAACAGGGAATGCCCGTTCTGCGAGGCGGTGGCAAGGGTAATGAGGTGCTTTATGACTCTNCCGCCGT
+
E)A4784.*H5E@;@5":6749B$$<(528'02&-!@)E4DH$08#98<)!$G94H)5#F/(:@><<8+&@H-A!.!8
@r9461
TTTATATGAATTTATTTTTTGCAGGGGGGCATTNTTTGGTAGGTGAGAGATCTGAATTGCTATGTTTAGTGAGTTGTATCTATTTATTTTTCAATAAATACAATTGGTTATGTGTTTTGGGGGCGATCGTGAGGCAAAGAAAACCCGGCGCTGAGG
+
9,%!+F%F9$0A7/=-:B2)"5=C?/@(04@&CB%-FB48*6=923-1A,DE-.#?*9()#9',5D%506?8:.%*/5*?(7.7E>.592>:8#&C="'C00.?D:#>@5.'#.!9"C5!41B"4,?G*H%)*;H1EE=@2;9@"7:#82A+E255
@r9462
TGTTGATAGATCCAGTAATGACCTCNGAACTCCATCTGGATTTGTTCAGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGC
+
.=G/,#!B<2BE0*15:.7GG%<,)7#6!$@<AHA:>+D<2%C(D7$23F%>CE+;047(D7ED>(E<9?'C)FGE9>&+-H>1G;70>-C:"?#DA!E5,@F
@r9463
GTGATGNGAAAAAAACAGCGGCAGTCGTTGAACAGTCGCTGAGCCGACNGGCGCTGGCTGCACAGAAAGCNGGGATTTCCGTCGGGCAGTATAAAGCCGCCATGCGTATGCTGCCTGCACAGTTCACCGACGTGGCCACGCAGCTTGCNGGCGGGCAAAGTCCGTGGCTGATCCTGCTGCAACAGGGGGGGCAGGTGAAGGACTCCTTCGGCGGGATG
+
3=A&5@82-7;'@&7B1C/7H/5E")(3;85>HCD</>)7;7A,&C?&A!.F2-.4$5>/57/@D#7)C87%,)*%3AD,!5-=G:'<'$.53("9E/8C64%%+07A6<97?<>:A(.@"%)FD/4%&##54C#8F4'."-,$FA?F-B7>D"!H2')A&4<@=@9=4=%/?'"-'!B(/8FB$9CA76((H6E$>-@AC@0>;A<7;A'F%&$?)=
@r9464
NCNNACAGATGGTTAACTTTGACCGTGAGCAGATGCTTCGGATCGCCAACAACATGCCGGGACAGTACGACGAAAAGCCGCAGGGACAGCAGGTAGCGCAGATCATCCACGGTGTGTTCAGCCANTTACTGGCAACTTTCCCGGCGAGTCTGGCTAACCGTGACCAGAACGAAGTGAACGAAATCCGTCGCCAGTGGGTTCTGGCTTTTCGGGAAANCGGGATCACCACGATGGAACAGGTTAACGCAGGAATGCNCGTAGCCCGTCGGCAGAATCGACCATTTCTGCCATCACCC
+
()!#)+)$+)"$''+!*!(*#&('+!$*%+#("&((%&+'!!$"')"#'(!&$)$#'"%&(+#+!%$)#"*"#))#+%$&#!$(()"!"(##()*+))'&!)&"!!%#!&$*''))("!''##!**%+*+)$($)$)(*#+('%$"%)'+$!)+#!)%'$+&))!%'&#''$%*)(&!%!#*&!($'%&!!)'"&'*"($*&%$('&('#!('(%!#*#("'#($"$&"'*&+"##")+)"*&!&%'#+&"(&(%#*+$'*#'&'$%()"'!)%%+$'((%('!""()%('&)(**
@r9465
GGTTACCTCCTTCGTGAAGACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCCGCCGGTTCCCGTAAATCCTCCGGTTGCAAAATGGAATTTCGCCGCAGCGGCCTGAATGGCTGTACCGCCTGACGCGGATG
+
*E</B8D@#&(HD3(CC-F85#<88*"$(7!@,2=&(':&5#%)G44/AB7*68@-02>'6/"?&'1<*+$7'E6F@3%124,G-&3!7':,@BA#?"0;4C8%0(-4%;=D?=F$B9D<=>0""9*9)=9!"DF,7374((D
@r9466
CNTGGAGCCACGGATGGACTTTGGCCAGACCGAGCCTTCAATACGCTTGTCACCCAGGAACGTCGGAGAGCCTTCCTGTTCAATATCA
+
)'@3(+A5>5"(@0+#(;A.GD4@!(5'@"(@+9)+&+@+:43&43=0>--0@4F'6A=7"GB</9:/+A)03F!H%3A@7484G%65
@r9467
CCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGTAATTGGAATTGATTCAAA
+
&.+.B<136D+G,+&$C/;EF3H="+HF$<+?#>,(+/5+G7A=7G48B=2."3*?!&H
@r9468
NGGNCTTNCCGGCAGGTGCGCCGATCCCGTGGCCATCNGATATCGTTNCNTCTG
+
):,$5+<(=C,8H&F$"8+'BA>2%#8/4>$E5@.134!C8>?@,2??$F84G,
@r9469
TTTTGCCCTTAAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCG
+
68824-$CC%AD-8$G=7%9BADF0@7B1<>+#3%9+;*B66E3,1%9F<@F07H>D=52A""'(F:"%'
@r9470
GTGGCTGATTAAAACAGAANTGCTGGAAACGCAGACCGTGGATTTCAGCGTCGGCGCAGA
+
#%%+!#%""**$%$"##*&'&$+%"%)'&*!$((($+"))()'!*!''#++&+"%'#'*$
@r9471
CCAGTAGAAACNGACGAAGAATTTCATACGTTAGCCGCATCCCTTT
+
=+8!C(+!%;#23G%79EC/2+8?@<A(F9-&H6+>7&F?'BED*B
@r9472
GACCGTCACGCTTTCTGAACTGTCAGCCCTGCAGCGCATTGAGCAT
+
B=8+B2"0A#0-;/';C.//*?%F2B0<<3;C?=B*B&;>"6H#A<
@r9473
TTTGGAGGGCAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTATCGGTGCGGTGANTGCAAAGAAGATAA
+
(>*99$9H!$*HE<$<3D#32*D-3#%@B@$?"6!%5.2;FE7/;0!-"49C65(',0=249!#9(/H)).&E$/AG&39D;
@r9474
ATCCACACGCAGCAGCNTCTGTTCATCCTCGTGGCGGCCCATAATAATCTGCCGGTCAATCAGCCAGCTTTCCTCACCCGGCCCCCATCCCCA
+
E;A&-=D7<?G4B#1>-*=GAD'<7(A-EE,>;(!F0C7F(,&0C=1=G('A:/&0@=3!$H?:D*CG!"+>.F"$;52<73"E:;.6;'1'"
@r9475
CCGTCGGCAGAATCGACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATGGTGCCGGGAAGAAG
+
-H<3B3')3H*E%31=)2'6;/.@F8?:)(...D+.#2"$;1*9.)1"**70B=E,(A2%%$9B>
@r9476
CTGTTGGCGTTCCGGTCANTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTANCACCTTAACCGCCTTTGGCGTT
+
D!*5-#79>@/C.=5#,@BC2'?#62H>8*'81#9,-3#B=$'#H')452E%$B32C04%8DF0)+08+G9=#-=B48FE/./3*
@r9477
GTATGCCGCATTGCACTTTCGTCCCTGGCAGTGGTCGTCTCTTTCATATACCCGNGAGTGATTTCCGTC
+
H9);4G4+,3G45E#0H5&FF'H=273H))9",&+9$2!8:/E8='9&7$7:$%%>;-:5-7G7-()<!
@r9478
ANCANNTGNNCGNGNNTNNNNTNCGNTNTNNNNAAGNGANANNNNGNACNTCCNCATCNGGTTANNNATATNNNNNNNNNCTCNNNGCTNANNNCNNGNNCGNCCCNNNTAAGGNTTNNGTCATGAANGCTGCNNTNGGNANTTNTNNATTNGNNAATAGGATGNNNGTGNTCNGCGANNCNGNANNCTNNGTCNNNGNCNGNGNTACGNNTCCNTNTNCNNNNNCTGNANTCACCNCNNGNNCAGGNTTNNAGTNCNNCTNNNTANANNNNNCNNTNAANNNNNTNAAAAANTGN
+
$"#"##!"##"$!"!#$!""!!"!###"!""##"$$!$###"$$""#$$#"$#!#!"#"!#!#$!!!#"#"!$$$#!!$"$$#""$"#!#!"!"#!#!""$#!"$!"!""$""#!!#!!$###""#$"$"$""$!#"!"$!""$"#"!!$""#"#!$"!$"!""$!"!#!"!""##""!!#$"!$""#!"$!#$""###!"##!!$#$""#$$$"$!!"#$""$!!"#####"!$##$!"##"#$#$#$$#""##$##""$!!"##!$#"#"!$""$$""$$$"!!!$""####$"
@r9479
GNNCAATCTAGGGGAAACCCGCCAGCGGTCGTGCTGTATTGTCTCAGGAACAGGATGGAATTAAGTCGCACACCCACAGTGCCAGTGCATCCGGTACGGATTTGGGGACGAAAACCACATCGTCGTTTGATTACGGGACGAAAACAACAGGCAGTTTCGATTACGGCACCAAATCGACGAATAACACGGGGGCTCATGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGCTCATGCCCACACAAGTGGTTTAAGGATGAA
+
!#&7>(AFC5.../8,(?;&>'.07&D-2(")5".5.-CE0&;:3H>%;CFG@C>FD@0$.;*$5E$D1DG??5FFF=A66@9;:$"%>5+E$5':=3'H*'("#-:88/?!BCE0?6/@4,9E'4("!,A1%:70H+DEH,H?@5",/0CF,;(9*26/!A.?;B&AB'4#=<934":.6'@F'3;H*A!&E<>-!7=/7C-'.5?$F+5-3/*</?C<:3F1E!3$!=!9;E<C"*.E"&?>E<@0D<B+$E@#A-%",6B*8
@r9480
ATCATCCGGCGAAACCCGATCTACCCAGAAATTTTTCTCNCCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTC
+
,8.,9E<-:;"4/C+.,;$5H;D,H+$?'(1;G2)664<,)5"$;#(B+/!$;%&6,C(1/1GAB&;$*"C18&*81F7<H
@r9481
NGNGCAACTTANCCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAGANCCGGNCCGGCGGCAGGGCTGACGTTTAACCAGACAAGCGACTCACTCANCGCACNGGTTAAGGCGGGGGTAAGCGGTGAGGCTCAGATTGCGTCCATCAGCCAGAGTGTGGCGCGTTTCTCCTCTGCATCCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGGGANGCTGACCACAGACCCGACGNCGGGGCTGACGTCGATGGCTCGCCAGTTCCATAACGTGTCGTCGGAG
+
""%%'!%*($$!$+#!(("+&(()(()''!+%)$'&("''&!)$)()#)'!)(('"&++*)*)#%"!++'("$"()#+!(&)(&+)#"$)&$()%#%&*%*%*#!!*"'%*)%+'#')+&!*'('&'+&%#+%%#+"&%!$$"'!#%'*+$'$*+)#'"'('#&"*++#$%#*+&$'*'#+"!*+()$#%#!$$$%%+%(%)$%"()$+*&"()"*!'&")"%+'!$#!!'+'!!*!+%!#*#+'''+(%+()#'(+#*#'*"'"*")%!&)+!$##'%&$%$)$$)''!&$&**#'')((&%&#"%$%+"$#(%!&&)!+$*'&')+("'!
@r9482
ANNTNANTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGA
+
#"$'(!"+"#(*&*')%)$"!)#!)(+))$$*'#*('&%*"&'*
@r9483
NGTAACCTGCCGCCGCGCCCGTTTAAGATCCGGANGCGCAGGATGAC
+
#+)%"$(!)')(*#%!##*+)!%')"&"#+&'$*()*%("!'("'!&
@r9484
GTTTGTNCCCCTGAGCGCGGTTGGTGCTGTTGGCGTTCCGGTCAGTGCCGGACTGTCCAGTGGGCTTTTCTGTTCGTTTCATCCATTACCACCTTAACCGCCTTTGGCGTTGCAGCAAGCGTTTCAGACGTGCTGTTGGTTGCACT
+
''='FB&,$"%7<:)(3D&2'<0,+#E#,8?C?G?@C7+G=A93B8:F@!;B4";2343$:9:22;.0?@'GG**>$AF&<G9)'E-B7C?0D:+3,":0C.&,%@%/3H'-(:<1B%?-F0B>;5=;D@!,6H++$7&#38#"D/
@r9485
GATGATATGACTATCAAGGCCGCCTGAGTGCGGTTTTACCGCATACCAATAACGCTTCNCTCGAGGCGTTTTTCGTTATGTATAAATAAGTAGCACACCATGCAATAT
+
$>&"1GB>7)C3$/C9&:.<=91(&DFDC+!#.)8G6G*1;)>5AC!&@9/&FF8><-ACE&D(CHF/<HG:&*><<&C84.*'1BD8>:&HAH*;D6/C!62D6/A;
@r9486
ACGAGAGAGGTACACCGACAAATGGCAGCGACGCACACACTCCCTCTGGCGTCACCGGGCATGGCGCGCATCTGCCTTTGCGGGGANTTACAACGATTTGGTCGCCGCATCGACCNTCGTGTGAAAACGGGGGCTGAAGCCATCCGGGCACTGGCCACACAGCTCCCGGCGTTTCGTCAGAAACTGAGCGACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTT
+
7700HBA#5,$&D$!$B-;@A#)@<.!%@)/*3F.2H3G(+7G337#B&4:)#6)7F)2H&!F&.'A>C$BA?:+H@7)'21,2!BE:3>>C;F-:,9"':57"G:F.'!++A#E6?-B6<.?G#4)&%&@#5E&>;6*4&+;F>+-5'&"4&F4./;A2/=#*$/D</"66!GB'&='1>C/0!:$8B&$3F$B*'?3A*,C!:&4#!3'!(74.C?DB.(9**!(?E%)B+5)'$A-H$D
@r9487
CCTNCTCAAAGTCTGACAGTTCAGCAAGATATCTGATTCCAGGCTTTGGCTTTAGCCGCTTCGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATNCCCTCGCCCGAAAT
+
'%%!(%+"!%+%%*)#%)*!&&()+%#*$)(%&&$"')#''()#*&(*#!#&+&+(#$#""""&&$!$*!)#$!"&&$!*()'*("+%&%)))+'%!#'"')$++&#'*)+!"%
@r9488
NNGGTGGNAANNNTNANTGGTTTNNTACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTCATTCCGGTCTGCNCNTCCAGCTCTGCAATATATTTTTTCAGGTCAGACACGGAAGTGGCCGTAAACTCCACCCTTCGTCCGTCTTNCTGTACTGTTGCCACCCGTTTACCTGTCATAAGGTCATGCAGTGCCGCACGNGCAGCGGCAAGTTCTTCCTGTCGCGTCATTCATCCTCTCCGGATAAGGCACG
+
!!(#*(#!&&!!"**'%()!$)%""%*+$%%!"##!#&#("(&"(+$#!#!$$*!*$$++"%+%))%"&""&"'!)#$+')%'$)#*$#*'+(&+**)*"!)$'**"&&$+%#$()%%+(++!))(!'"#)'*'*+$%$(&)(!%(("#$')&%$+!&*(%)'+&"(&&)&*'%+$))$*"#%+'*"#!%(*()%%&)%!*)"&*%!##""(($)''!(!##&%'%!'%')&&$$(%$)+)!$%)*$'&')+
@r9489
TTAATATATCGCCAAATACAGGTAGCTTGGCTNCTACCTTCACCGTTGTTNGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGNTCTATCTGAACGCGCTCTCCACTGCTTAATGACAT
+
0:<159G:(2D,-?0,/A%140DB<GF);#&*F8%?=D>.5FB4<9=2;-6D?G/.>C>6&$$-?D=/C:&&3-)?/.+,E94"62&F+H;?'.*G%6C.G;B909396-D=,>'<38'-9*#;H#@'59B9H3*$0CG/0:
@r9490
CNGGCAGTTTCATCCGTGTCANCAAGCTCCTCTTTTAGCTCTGCC
+
'"667;-@4(9<9*"#%*?C$<+$1G5A!C*-2#F+"*)55$8'3
@r9491
AAAAAATTCTGGCTAAAGCTCTTGCCCATAAAGCAGATGATT
+
<D;%>?5*B".18!76*5"G46#*G-G0@F0=>>H39>B%19
@r9492
GAGGNCATAAAGTCAGCTTACATGGCCCAGGTGCAGTACAGCATGTGGGTGACGCGAAAAAATGCCTGGTACTTTG
+
*A1<-/'9H,A?2)E5$A4/)H2(1"DF/D!,$D!+C>''($+$/!3?A*-AC"/-)13,C"B9G'1196D+&;@9
@r9493
GCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGG
+
8;-6.D*8D'ED&6D%2!2(!#(<=9.6,$4=-3H1D=>619@10=C6F-E"8+)!4>>%G>!B0(#DG"8#H&5.%6B#=":DCA#;5D<B!;)0BFF'*G!=!"-8F@F(!.?F;,$@;=?,9.5(=;
@r9494
NTATGTTCATGGATATTTGTAACCCATCGGAAAACTCCTGCTTTAG
+
"$H!/@'@@D0'@="D/;;+D#!/;/B%<!?C:="H;"D"03.>0+
@r9495
TNCTGANAAACCACGCGTGACCCCACGCGCATTTCCCCGTACAGAACAGGCAGAANATTGCCCNGGGCAACCATGTTATCCAGTGAGGAGAA
+
*&**($"&'%%&((*)+('%"&!#"$"$%#&'"$)*&'&)''!(%!(!$))'!$$*&(&)%$)$'(%)+!$*!%'*&$&#)!+!#$!++$*'
@r9496
ATTTTTNAAGAAGTATTCGATCAAGTGCGAAAAGATTTAGACTGTGAA
+
?9=9DE=?/?2A3%$'F1:G(-='<H#3#;9B,.-@?%3<?,2FA)B+
@r9497
ATATNCNTNCGCGACAGCCGGACCGCTATAACCGCACTCGTCACCGCGATANGTCGAGGTGCAGGTGTTGGCCAGCATGATACGT
+
*%**!%&(#)')+&'&$"%)+%'+#"&$)()!'()'$'*'&#)&&"%)&!$''%+&%"(#*!(')))((%&#''#'&!#$#'"%#
@r9498
CCAGCCGGAGGGCGTAACCGACNAGAGCTTNCGTGCGGTGTCTGCGGATAAANCAAAAGCCACCGTGTCGGTCAGTNGTATGCCCATCACCGTGAACGGNGTTGCTGCAGGCAAGGTCAACAGTCCGGTTGTATCCGGTAATGGTGAGTTTGCTGCGGTTGCAGAAATTACCGTCACCGCCAG
+
4EAB?@0H"G(G+B3-!'E@,.7-&>>+4&GHF;%54/>%,-)>%D7%>8D<(,%>G=%<F>$D>3*6056$9$!G$/1EA:D?+&@)03(:(&:375,!56#67B;-9(H=/HC#!E8D+8".(03/C9>0*=,!D%DB@!A83:/<(D/3/6+(32:;!7/<HD*").&-%:6.A*6.2.>
@r9499
CATGTCGCTGCCACTCGCGCAGCAAAATCAGGGGTAAGGAGATCAAGACTNACGGCAGACGAATACCTGAAAATTTATCAAGCAGCNGAATCATCACCATGTTGGCTCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATNTATGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCAACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGCAAAGAGATTCTT
+
E-'AFCDGDE@+)8!4,?!1>79!G%7B@*5BE&177A>&##%1$2,+:6G!!F$3"@(%4%)1.0&..6&+".02'65A<.5"*67HB1*)9(E5!3>;.>0.E8%HGF(<E*GD5G/*<",#!67))B-H3=*(/$C4#7F#$@+D/0!74$&AA"EBF#8-CE4@.7D;&E.":&-,DC.7(+/D7=@8C4)E:%!+9"'.,#=D84#<H5G640+07!E/*$0.1:=@0EC<6<)/"2H$3"*,8>=;HB+B%G=AH:9-?=+H5F+E&6(3>43:(68HF3?=HA.D1!&/E('9/
@r9500
CGCCGTCAGCCCCGACGTCGGGTCTGTGGTCAGCTTCCCGAAGGC
+
-G1,H.*;F75C7%+'E3)B1834EG;FEC.%$HE5(.H=E+66#
@r9501
TCCGTCATCATCACCGGATAATGCCAGCGTCGCGAGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATCCGTCAGGCTGCTGATNCCAAG
+
HD'A@4C4;EC8?D0ADH>;4E>H0&!H'@<=(6:'E=5@9'5838->G><#6*4(/G">),(;$=::!:?.G-3(:*.>,+10B':(,?FBF(;B
@r9502
TNGNANTNANTGCTTTCACCTAAGGAAAAAAACATTTCANGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTANAAAACCAATTTTAACATTTCCGATATCGCATTTTTCACCAT
+
'#"%)!)!!!+%(()!%(+!#(+#!#&&'#!*&"&(&()#$'')!&(('"&)$++$)"%'"#()%'!")&*&*(!("")!#'(%%$$)$"&!$"$&#**'%%#!)+)+&!))'')!&!*+'(*$*)+''#()!#%!'*")((
@r9503
GAACCAAGATAGCACTCGAACGACGAAGTAAAGAACGCGAAAAAGCGGAAAAAGCAGCAGAGAAGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGCCTTAAAGCCCCGCAGTTACTGGATTAAACAAGCCCAACACGCCGTAAACGCCTTCATCAGAGAAAGAGACCGCGACTTACCATGTATCTCGTGCGGAACGCTCACGTCTGCTCAGTGGG
+
)+H9B9A$@.%#%"DH)D!+C!#"6%2$'"AH<..?@C#5.3%##<>!*3%>.=;'@&#%$&12E.B/">%G"7H+%<&?=DC<A?#4G6C5/BH/0.D4;8(</D<D*BC?/("!3**=G>#?;=2G%."5+<6'=##8%.,@G8.0G4*GC)<('08G30>AE8(<3F5$@%&0A2;<4?D$+!3:1(:'>#B94EB'1/FBED7G?F1#4DA=27>C)@EH+;CFD7%>&<'-):A6
@r9504
CTGACGATGCACGAATGTCGCGGCGAAATATCTGGGAACAGAGCGGCAATAAGTCGTCATCCCATGTTTTATCCA
+
>@*4$$CE'*08E652,9;6,#:7%=3&G,:39?#4$4*<5(@?46:80=2"8%%A>:F<C?6//-514:17<?+
@r9505
CAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTACCCGTCTCCGCTCGCTGGGTGAAC
+
(>'F*7B31H,6&(,"6C.'FAE>D@7.=63D#EC"523F/C9&9FG<A?9:!1H8$>8%$!7:(4B/,+4E0%$4%#/&5+%("F#.<C3:+:D%0!:"@==,E*?2D1D<0H$0*@?/;>.C!)9*0B750#:HG1!C;501!9;5D;
@r9506
TCTGCCCAGGTCTCCNGCGTGCCCATGTTCTCTTTCAGGCGGCGGGTCTGGTCA
+
$=!-E7>1F3CDG!?@)%>,'8(08.5BBA/<=DF!40+?;!24$-26,/5>-@
@r9507
GATTGCGCCATCCCCATAGCAGCCATCACATCAGTACCGGAAAGAGAGTCAGAAGCCGTGGNCCGTGGTGAGTCGCTCATCATCGGGCTTTTTGGCGAATGAAATTTAGCTACGCTTTCGAGTCTCA
+
AG.5'-DF13/AH@)6B(,,=)#BG$4!#:/%$8(A#$,5;H:#EF0G*7+7#3C(%+;1(03!47!$#C3)E?B0(54&5((=7GD$;04)/8)+@!3H/*<.6,E+E/*/F:51&1!F2::(E#6
@r9508
CCCATCGTCTTTCTGATTTAANAATAGATGATTCAGTTAAATA
+
+(*(($#"'!(""&(%')#&)$)+)##!&*&'!%&('%$%!+*
@r9509
CGAGTATCCGTACCATTCAGAACTGGCAGGAACAGGGAATGCCCGNTCTGCGAGGCGGTGGCAAGGGTA
+
*?*-?-#(.<E=<3=.7.1FF,$'C;3!**2+5&->2$D&A&%)F>(F-)HF0C8BD=/1#6)4(.GF?
@r9510
TAATCAGCCAGGAGTCCCAAAGAATGGATCAAACACTTATGGCTATCCAGACTAATTTCACTATCGCCACTTTTATTGGCGATGAAAAGATGTTTCGTGAAGCCGTCGACGCTTATAAAAAATGGATATTAATACTGAAACTGAGATCAAGC
+
4FG)$C>,:8'+>4.)F1/?H%&($9244-8":<!=%$E,=<-)F':8%03B@C%;@!*H:@!@--1G&8205)G#<(H+C!6$:10%37:<(#6>3;5;6-).GH=:!??16>.7E2%;2?:DF;287CD(7G?&/?#1=+E=@+=.>54C
@r9511
NNCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACGCAACGATGTGCGCCATTATCGCNTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATC
+
(..BF>E*/,EF@7;:>FHF34=;7.,"6#6/3+FG69=C)D/164+>9=7B"%./'.!3!$;,=A66?;;1E*@.)1%4$B9(>E%4'F)"-189-:<B(A+D=0&(5B*2CG"A5?;(0//>?G7C6@3#00*?&
@r9512
GNGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTNGGGGCCATTGTTTCT
+
*#@%G(238!?;A,?,;)+))'F-A(,"D1D.(@'*?6GG)*C.:@%5*>)H*98#2>E+)1A6'"(+%F:9)G.39:"F=;DAHA.,B-#D027>#:#C$F-2>;%E26<D8=<!E0067
@r9513
NNGAGANTCNNNNNAANNCTATNNCNCNNNNATANGACTNNNGGNCGTNNNAGNTGNCNNANGTNNNAGGNNNGNACCNNNNNNNGNANNTNGAGNAGAGNNCNTNCANAANCAANGNNNAAANAACAGGGNG
+
!#!!"#"#$"!!"###""#"$"#$"!"!!!"#!!$##$!#$"##!#!$!!!!!!#$#$$!$!!$$""""$"#"$$$#$#!$!#$$$"!""$"#!$"!$$"#!#"#!!#"!$!"$!!$#$"$"!##"!##!!!!
@r9514
CCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACNANTCAACGTCTGAAAGCGGATT
+
FA;>6=C-3==$>7:#!@A!AD&E?4!.49//HDB8FC+7!<7;E%6+H&!70=851A*
@r9515
NACAGGCGCGCAGTGACACTGCGCTGGATCGTCTGATGGAGGGGGCACCGGCA
+
+!#*+%"%(!!#)'#%#'!++'%#&*!&''&+)*"#%'("('*$+()**"'#%
@r9516
GTAGAACGTCAGCGTGGTGCTGGTCTGGTCAGCCGCAACCGNAAGAATGCCAACGGCAGCACCGTCGGTGGT
+
778;<6<1H<*0,&56.96=DF*.H)@H765D4$;=5#A>G87H7+3@+05D:;;>0(=,,6H.:<60;>0-
@r9517
TNACCGCACTCGTCACCGCGATAGGTGGAGGTGCAGGTGTTGGCCAGCATGATACGTCCCGGAAAAACAGCGCCATC
+
'"<D6=,;69;#+H4*$1D8:-%('-9F?!4F.H),01BG-A()5HCD;';/)F$D4BA@66+@GF1&BF)',G'>'
@r9518
ACGTCCTCCTTTTCCTGCNGTAGTGGTAANACCCNTGTTGGTG
+
1(?"E;F''@.+%%HF<65F$@1$%6<%#<E"&D9A=B0033#
@r9519
ATGCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGCTCGCCCCGCTGTTTTTGATGAGGCGGATTTTTCGGCAGTTGCCGTT
+
3-.)$)<5+$=*<,D&H'*$.!DG7G4$D=<GA";"(H2>!,"4A+"#)35501@$7G?'6(G"80G,DED7%%984)(9'/5?B48.<
@r9520
TACCCTCTGAAAAGAAAGGAAACGACAGGTGCTGAAAGCGAGGCTTTTTGGCCTCTGTCGTTTCCTTTCTCTTTTTTTGTCCGTGGAATGAACAATGGAAGTCA
+
AG5BB38-DF/8)D-H6%A)66A3"),:FAH!#CE@9D500'A&B37:AG'6&+*AD!-))G>7.&!"-0A/'#D4!+2&(H)2687%=(>A>G<7!$A*-=5=
@r9521
CATGGCCGGAGTGGCTCACAGTCGGTGGTCCGGCAGTACAATGGATTACCGTAAGACGGAAATCACTCCCGGG
+
B4@;%0,>,2@,=E.)&783++.>3)-3F9/@':;6<60E6>=3?)*;#8!*CE9&$3'2*1/-#@11?):6(
@r9522
TATATTAAAGGTCTTAGGGGCAACAGATATTGAAGNGGAGCTT
+
B#8H'%#-.G0@:!2+*D5$74"/(9>-&$=CG:&,<((/7:H
@r9523
NTGTTCTGCTTACCGTTATCCGTTGTCTGTATACGGGGAGTTCTGGCTTTCGGTGCCAGCATCTGCGCCACACCACCGAGCACCATACTGGCANCGAGAGAAAACAGGATGCCGGTCCTACCACCGGCCCCAATGGCTGCCCCCCATGCTGCAAGGGTGGCTCCGGCGGTAAAGAATGATGCGGCAATGGCGGCAGCCCCCAG
+
!5F@-?"*(C1+42(*@1<(%D-:,@+*=)'B1%D;C:%</@*1""(3DAA;'"GE&'6;#@/F/<+)';:.4+0B=<=98)2=$(:!;0B2+3=&*C@E8=":61:()2&""H"%.@8+!22-.>B8/1H:/!*C>?*.?0>H:8C2E:/75=?-'+;#BA+"2=--&(++1G?7B<#-;(/9=G?#:H*:07H$-6CA4*#
@r9524
GTNNGTNGNATACGCAGTCAGCGATGGATTTTATTCTGGGCGCGAACAGTCAGGAGCAGCGGGAAAGGCTGACCGGCTGGATTGGTGAAATTGCCGCGTATTACGNCGCAGCGCCGGTCCGGCTGGGAGGCGCAAAA
+
*&&$*!$%#(&(++%%"""$#$*%++!)"%!+(%%%($*#(+*"+("!&(!"#(*%&)#!*"+$%)"""%)&$%'!*'$((*%'%#$+*+$(!!++**(%&"'*'!*")!**$")('#'!#++)+&#(+%"*%%'&(
@r9525
NNACAGAGAANCAATGGCCCNGAAGGGCCATGATTACGCCAGTTGTANGGACACGAACACATCAGGGTCAGCCAGCAGCATCAGCGGTGCTGACTGAATCATAGTGAACTC
+
#+&'!(!""'%"!)"$*'!#*'&"!"%+!''+$%%((%&*+&'+)+#$%))'&$+!%"!!%%'%%#*+"*)((&)()"*+'*+!'(#))&"))(*)!'*"$%&(&'%+#+)
@r9526
TTNAGCAGGAAGTGCTTACCACCTGGCCCACGGAGGCAATTTGTCATGCTGAAAACGTGGTGTACCGGCTGTCTGGNATGTATGAGTTTGTGGTGAATAAT
+
1A<#C4F=8E2A??C0%'!D*8@C>GC<:A"'@A;<,A#&46327#)G1(:?,G%8!%(H4.!$A)F@FCD(#6D@$D22$4)3#378+$:5)3@@FDH=,
@r9527
TGCTCAGACTCTAACTCATTGATACTCATTTATAANCTCCTTGCA
+
#4"D3G?G57"8D>%4*@)53/8-C,C:@+5:G8;235;)!-GB5
@r9528
CGGAGTAGACGAAAGTGATTCCGCCTACCCGGATATTATCGTGAGGATGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATTTTTT
+
4#-?C?;F.F2C9:"87.DE=;;<1!:09F*.");"2#>$B.9E'B:/D$51#4AE.0E)*6&:"3>?4#.*C!8:4)*!30-!A%=5-%<33%1!A>E=75E)*G4=H2
@r9529
AAGCGTAGCTAAATTTCATTCGCCAAAAAGCCCGATGATGAG
+
0=&C(+DCD!D@?#'=545<.!4&6>@50CA@/#>1)*683F
@r9530
ANGGCGTCAATGACCCAGGCTGAGCAATTCCCNGACCCTTTTTG
+
&!(*#%!)*+$+**)%"$%#+&$'((!++%$%()+*#$*"'#%$
@r9531
NTTACGCNGCAGCGCCGGTCCGGCTGGGAGGCGCAAAAGTACCGCACCTGATGCCG
+
/D+-@C55=2/)?7;F"F0&$H)#65"C++A$?)5"8/D419+C+G/:@/E*)860
@r9532
CTGGTTGCCGCCAATCGTATCGCATTTATTGACCCGGCAAAC
+
2GC&21E18:H4/63&&:-$8)@+940:-"5B!'A!'=@?'=
@r9533
CGNCGCNGNACNNGNNNNAGNTCGTATTGTTGACATGCCAGCGGGTCGGGGAAACG
+
%#&(()!#"""!"&"%#""%(#*++*#)(&$&)($#+)*+)+$'"+$(+&)""&!'
@r9534
ANGGCGCNTNACNNATNCTTGATNGTNNTGATATCCGTCAGGCAATCGACCGTTGCAGCAANATCTGG
+
"$##)&&$(#*###&*$%)&($(!'*&%+%(&)%&+$%"(**'+")!*)!$)""!$**$)+!)++&+'
@r9535
ACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCTTTTGGTTCCCATACCGTATAACCATNTGGCTGTCCAAGCTCCGGGTTGATATCGACCTGCAATNCGGTGAGCGGTATATCCCAGAACTTCACAACTTCCCTGACAAACCGATATGTCATTGGATGTTCACAACCTGTATCCATGAAAACGTAAT
+
7.!1.D'?%8@E'#&0AC(!:='7(';'&02=9D)#@6&(-4:25F!C?7).)9A$3%"16G=20@1%#9B0E1!$G1=&0@/7$!;&%+3'DE('2F132D,:"$G+::!+,#F4)'$B$=;.#*%:5,9)'.<4-$G#,FG+9?9)$<?78HG-0E3;,5"F>(.$.936>7D</7AC!9($:/91:F%,;6:F2D:F9!
@r9536
NGNTTNNAGAGNGNCGGCTGTCGCGGATGAATATGACCAGCCAACGTCCGATATCACGAAGGATAGATGCAGCA
+
#''')%%(#(*!&"&+)!#$(%$""#*)'&(#)'*)%%$"('$$)%!%!(!+%#(#$%+$#%"&)("!+)"+*+
@r9537
GACNTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGANCC
+
'!#'+)%')*'*#!!)%*%"&'%('&"+*!&+&$!$!(""'%%*!)$)"*##
@r9538
TAAAATATTACTTCAAGTCTTTCTGTATGAAGATTTGAGCACGTTGGCCTTACATACNTCTG
+
DF3;;*:!,%-((%1"38%5,B?AC<2,<"/?4>7,!A%.H3>#%;):,&E<79F>C4>:4D
@r9539
GGGTGCAGCACCTNACNGCAGAAGTCACTGCAGACAGCGGGGAATATCAGGTGCTGGCGCGAT
+
!&+("!!%!$(#$"$%*"'%("%*$%#(('("%"%%'$)"%%((++$+)'"%!&)(!%+!")#
@r9540
CCGTTTTAAAAGCGATGATAATGAACAGAGATGAAGGTAAAGTACAATGAAAAAACTACCTCTTCCAGCGAGAACTTATAGCGAAATGCTTAATA
+
426%7/>H7'?<((&9,6'5$E!=1F(D5%592HE68%4&0?A)E514?*B8"B-8FC<,:C<#>0%7%;+B?C9()%4;.$:B=0DF09;#A/+
@r9541
TAGTAAGGGGCNTACCCCGCGCGAAGCGAAGGACAACCTGAAGTCCACGC
+
!D'.=+4G.D1HE$2557F$@#=<C@%&F;>=:9=:A+:.C=,6(1E8(!
@r9542
TCAATCAACAACTGTTTCAGCCACTGCTTCGCANGNTNACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGCTGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCCGNTCTTTTCGCAGATATAACGGGCATCAGTAAAGTCCAGCTCCTGCTGGCGGATGACGCAGGCATTNTGCTCGCAGAGATAAAACAC
+
&D='16.%=/"=*1'92"<>0#8E*)4G&!0+BA@,6A)F>%$$59"-)/8!1.''6;H*47EH(FFE?=#D;9H2FA)4>A6&6&;8>1@<2-4BBD)?!;FC81=&9?8C994%(35>--30D2"*>,15-0@#/#>+%6;:!3)52;>3F07.>D8*))*"8!C;G*:,%(<0E6(B40&H$-F"7:&H6&0!,/'69(C7$.#@%*!#
@r9543
TTTATAAGTCTAATGAGGACAAATCCCCATTNTGCAATGTGCGAGAAATGACGGATAC
+
/13H<G'$(@=E=6'/"??G(5G&!7#H6,0,,%G2(?*E>3++(F@)3&'0!!&C90
@r9544
ACCGNCANNANGTGNGGTACNTNCGCNCCNCCCNGCCGGACCGGCGCTGCGG
+
#*()')#!"%%()**&('*(*'"!((+$(()+"!)(&)#"#%+$"!$#"!$+
@r9545
GCGAATAGACCGGGATCTGGACCCGTGATGGCATTCTCTGGTTTTCGTCATCCGGTGAAGAGATTGAGCCACCTGACAGGGCACCACGTCAGTAACGTCAGCCTGCGAAGCAG
+
8G6)>!1#7:+2$B2-?7#.=%172C2F0/(4@1+75>,G!#+8#(:EC')5;?+AEE-:DH&H+9*H%%#+D1!9,?+H!H@92,1,2%%('9%/%2"7@;(?&;H(3!E.3
@r9546
ACAACATATAGTAACCCTTAATTTTATTAAAATAACCGCAATTTATTTCGCGGCAACACAGGATCTCTCTTATAAGTTACTCTCTATTACATACGTTTTCCATCTAAAAATTAGTAGTATTGAACTT
+
#)!+$5#<%!9$,(D'2><+93EB:!4D8%;B81ECHF-5<8;??23;3196,E:C,0F+C?@2A.)>!A94+B+>77-+@@0B!@4#0?@82/(!6-1A;%3$"HC:7-G3,E&)@'8)'>F49;B
@r9547
GCACGTCNTTACCTGCCCGTCGCTTTTGCTCCATTANCCAGAGCNAATATGCTGACGTCCTGCCACCGGAGA
+
071?B=-2H%A+6.5?G9HC<:FE*C'8*2)284A(!0D24DD310H!=$1G'!%G3/B5%9:5DC%1F0#F
@r9548
CAGGAATCTGTCGCAGACAAGATGGGGATGGGGCAGTCAGGCGTTGGTGCTTTATTTAATGGCATCAATGCATTAAATNCTTAT
+
B&=A%E=G!)"2&"&H5":@&>$);8D7,(5"/,AAC"=3;9%;88?8D.')#.#G2B$"=#BGD2$)F#9+,DG=12#C@4,/
@r9549
GATCCACGGAGGGATCATCAGCAGATTGTTCTTNATTCATT
+
-(8!&&')5G"5AE8>C"$>/(8=,<#@8A98,':E*,AD%
@r9550
AGAATATGGNCNGCAGCGCCATCAGGCAGAGTCTCATGTAACTGCGCCGTTAACCCGGAAGTGCTGACGTCCCGCCCGGCAATCCGTACCTGATACCAGCCGTCGCTCAGTTTCTGACGAAACGCCGGGAGCTGTGTGGCCAGTGCCCGGATGGCTTCAGCNCCCGTTTTCACACGAAGGTCGATGCGGCGACCAAATCGTTGTNAATCCCCGTAAAGGCAGATGCGCGCCATGCCCGGTGACGCCAGAGGGAGTGTGTGCGTCGCTGCCATTTGTCGGTGTACCTCTCTCGTTTGCTCAGTTGTTCAGGAATATGGTGCAGCAGCTNGCCGTCGCCGCAGTAAATTACGGCGTNATTCGGCACTGATGAACCAAAACAGCACAGCAGCACATCGCCCGGCTGTGCCGCTGACAACGGCACCTGATACAGCCCCGTCGCNTCCAGATTAT
+
*!%(&*((#")&$&+()*()*)+#)$#!(*'%'*"*)$*"#!!%")+(++#*)#&&#((#&%*&('+$'")*&&%&#+*'*"+)&(%()#$(+'#)*')#""'*#&+%*&)+)$!"'+!#!'))!%*)!$"+$$&$&)&*&+&$$#'%!)*!'"'&$('$%)$#!'*"!+"'%)#'"+"(&&+#$%*$(!'#+"$"#+#$)($%#&*"**)*&&!&*)+!#%)!)"$)((%&'+#)')+'%#))!')!*()))%''%#%'')*$$%*&&"%+%(*!*+%&*&""#"&%+"&%+"!##%#!!&!*%**)#)($!!(("!)"##$##$"'$'*%*#!"%!$$$%%$)!#*!)'*!++&)%$(+*'&#&!!!$('%*"'%!*&!"!$!')+*#*)%*')"$+++''((!%)(%"+$#%''&+"+')#""%$+)($#'+)+")!*)%%&%*%)!
@r9551
TTACATTCAGGATCGTCTTGAGGCTCAGAGCTGGGCGCGTCACTACCAGCAGCTCGCCCGTGAAGAGAAAG
+
8581"A-!#.D@&6)/0%<8/6(H)@"A+(0#>&%'!03@-):1C(/B#6:&A@C68.C>4D'(2E;/=)G
@r9552
GGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCANACCGGACTCCTCCTGCGATCCCGTCTGATACTGTCATCAGCATTACGTCATCCTC
+
'E+='-E78,@(9($>1+1"*09@2<&:G3'=C"E@(?>375.(1".C;/%(+865*2>2H5#"#-AEB3D3.-<-6<@#GE,C=##9?&,,=+C";=</28@/#2/<G;/;4?&'B%0-E2F",1@G4)(5H;<6(7F44F1-'A.8+EH/%3*?.<>5*'5;,F+F$CG.E316>()#@@2E1::?!0*?;286C=-D,@?*6F9'5%#D$:<*87C>B*+F'#%=0).CEA!@ECFB>?GA6'0<?!3#?FDD?3#4$#%F&ECD#B?&5?HD=#<<D;($)*A(5/CE1/)'2=*<9)H&1@?9G#>=A!<?(3:EG(,%?C86"*6H@EF/6?3CDH#11#E&.7"*5'DA="A(+<-"'@=(7%,D@64AH(>..F
@r9553
NGTGAGCAGGAGCAGACTCCGCCGGAGGGATTTGAATCCTCCGGC
+
,3(!D#H6/H7;C7;!A8)&'9":HF,/:<@4E,.61">G$-C6G
@r9554
GGCGGTCAGGTCTTCTGCTGTCCCCCACTTGNTGCCGCTNTGAATTGCAGCATCCGGTTTCACCACAGAAGGGTCGTCAGTTTCTGGCTGGTCAGAGGATTCGCCAGAATGACGAATAATCTTTTCTTTTTTCTTTT
+
+$0F?##'0<@9E034GD.C5@E,=$>1G$E0*C(<G>B,%;0H5:0F)5-2)/;!E2.!C+/6(E=B7=,'($C@!E,"$7"%G#-(?<5FG58H',:7<(B#0:-8(1(!!#00+9;#7#2@;,;8#51%E>,G*
@r9555
NTGNGNTTCGACANAGANNGNCAAATNGCAATCACTGAAGCTATACAGGCCAAC
+
"&%#&%(*#(!*(#)'")!*!&*!&&"%(+*$$+)(%!)'+(#&&$&+$++'$$
@r9556
ATTCCCGGATGTAATGGTGGCTGACGGTCCCATNTACCCGCTTATCGTATCATCGGCGCGGGCAATGACAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTCTGGCCAGGCCGCGCTCTGTCATTTCNGCTGCCACACCGGCGGANACA
+
!%!'+!++'")!+$($#!"!'$+%%)#%'""+(+"!'+!#&+!)))*"#$"*(#!(++*"$!**!)!%)*$#'$%!$%#"+!)"(#*(&+"%+$%)''"%$#$$!#!*'(+!%$*+'()+$($!%&++)*(!")+!%#$)%%&#))*(%+)$"))&)&$*(+%%$%++$'$"%$)+(&+
@r9557
TGNNTTGTGACTCAGCCGCCGTCATAAAATGGTATGCCGAAAGGGATGCTGAAATTGAACGAAAAGCTGCGNCGGGAGGTTGAANAACTGCGGCAGGCCAGCGCGGCAGATCTCCAGCCAGGAACTATNGAGTACGAACGCCATCGNCTTACGCGTGCGCAGGC
+
$*'(+%'!''*(*#(***!)$*#)$$'&&#'+%)'#$"'++%$!"#)"!!(*!&$"!#%))!"(!*%!$!$!'!)"$)&+#*!'(")#)"*!$#!$$#*+$$*(%$&$&*"*$*#$#($"&$)+!"!(*%)!!#%'&'+)#&'($#)"%#%"(+(++%!**#*!
@r9558
GCTTCATTTGGATATCAGAGCTATGGCTGGCTAGCANNAAAGCAAGCATCTACTCCAATAAACCAATACATACAATGCCAATTATAGATGAAAGACTTCAGGGAATTGGAATTGATTCAANTAATAATCAAAAATGTATTTCATGGAAAATAGTTAGAGAAAACGAAGAAAAAAAAC
+
&(FH/E@7*B$-B<)>':/82E?(F997'"A@C9CA'2)3C==+8$*!1G#0%D!*0E9H->&A@'@A;1H#D02B4G34&5454B(D1!*(A$9D537&"A.$-9)7-&66"H:-*E.A!G97:DF)1=@$C%94H,>&?!?(=;:&5*DGE=(&59(3>>41%+8=5$C.8-'=H
@r9559
TNTACAGCGGTATCTGGGACGGAACGTTTAAACCGGCATACAGCAACAACATGACCTGGTGTCTGTGGGATATGCTGACCCATCCGCGCTACGGCATGGGGAAACGTCTTGGTGCNGCGGATGTGGATAAATGGGCGCTGTATGTCGTCGGCCAGTACTGCGACCAGTCAGTGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATCACCTGTAATGCGTACCTGNCCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGATGCGCTGTATGCCGGTATGNAAAGGGCAGACGCTGACGTTCGTGCAGGACCGACAGTCGGATAAGANGTG
+
!")&+#(#*#!$)**"&$&)('")$'##&(!&#!!'%%&(#%!*!!&)$!"*%+%!(%('''&%#!'(&%#!'+*)($'(#$%&'%&++%))&#+"#+(""!#%($(&!&$)&+'$(%'!##"&"&%$+(('+%$!))$$&%!$"#!"%)&#"##($+'&+&")!#"%!'#($#)!#(%%#"*"%$"$(%')"&*"#++%"$#&)!*')"""#(##%(!'%*'&+()&%)"))'$!!"$(**('&("$'$)$#++%))"#"$($!*'#($*"#'$**!%$*"*!%%')+&++"&#$&&)##!+$%#""&!*"#'(&")%"&($'$*&%)+%#)!!&%*&)+&%
@r9560
TGAGGAAAATTTCTGGGTAGATCGGGTTTCGCCGGATGATGGCGGAAGTTGTCA
+
B7F39-59@-:;?1F=)6?@)*&=A56%<,@HD/6&)1@4$@*8!A$:HEA+$E
@r9561
NNCGAGTTTGGNCCACTTATCGCGGAGTTTGGCCGGGCTCAGCACGCTACCGGACCAGAAGTTGTCCTGGCANGCCCAGCGGAACAGCACACACATGTCGCGGTGGTTACGACCGTCACGTTCACGCATCAGG
+
&'E*@;388>7,E##HGB:8(&():-&+4>/'B"32H880H9,7.=38D9%5@??D-G*3)'/E)71:3!1?6.2#7,D#,0.#.).(6F?>)=++146&,DD"5?39D;5%F*@4$:,=32'82/H/-A<4/
@r9562
AAGTCGTGAAAGAAAAGAAGTCAGCTGCGTCGTTTGACATCACTGCTATCTTCTTACTGGTTATGCAGGTCGTAGTGGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCGACAGGTTTGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTG
+
9%)&=;+@H+"487.55/83$)8A&%13++08C2.&""@D9;<B&7>"A#5,7%*A!:1$2*A)@#,GH8AE*4''%C&8&8!0?/:74,:)@#97;7>043$,):9'>4"#>%:=EG4B.$B7,+HFC8E1EC9*1=D5&G-=+HF07?("08D0!G"71GDH,?*B542AH"H'A)2)($4HF"D$D=D#71
@r9563
TTACGCGCCACCTCTTCCACCATCAGTTCAAGACGACGCA
+
G3D*3$#2E8)4:8-@/6."?<-4#B:4<#=57-'766DH
@r9564
TCTATGNGAAGCAGATAAGCGATAAGNTTGCTCAACATCTTCT
+
F+3#.H>*H0F<!G@G89'=)#D$,:$)?/H/$!*@>G@/2<3
@r9565
GGGCGGTCNGCGTGACCATACGCCGGGAGGCGGCACTGGCAAGCGACTG
+
1024CEB21>/C18F&'<=,#%/2%$F4*'!+1?'?;+*=1!CC(%01E
@r9566
CTAGGNTCNNTTNTCTCNGTCANCTGCTNNNNNNNGNNGANNGTGTGCGGNTNNNNNNNAGNNNNATTCGGCTNNTCACNNNATNNCNNTCANNNNNTNGNNANGNANNGTCNTGANCNTGNNANANNNG
+
##!"$""#"#$!$!#!#"#$!#!!!$!!"$!$!!!$!##$!"!!##$$$$#$$#!!$"!#$""!!!!$#!#"!!##!!$!!"#$$#$"""$$$!!!!$!$!!"$$#$"!$!!"!!$!"$!!#$##$"""!
@r9567
GACNANNTACGTGAGGTGAATGTGGTGAAGTCTGCCCGTGTCGGTTATTCCGAAATNCTGCTGGGTGTTTATGCCTACTT
+
'*'''*&'"($#+("!&)$!##'%%#'%&"'"%*&$**%"*$(#"&&)"$"+($'%+)''$&$!('"'&%))*"&)%*%*
@r9568
NGANCNGAAGTTGTCCTGGCACGCCCAGNGGAACAGCACACACATGTGGCGGTGGTTACGTCCGTNACGTTCACGCATCAGGCGGATATCGTTAGCCCACCCAGCAAAATTCGGTTTTCTGACTGNTGGTGCGATA
+
#)&#)"'%+!)%&&(+&%&)$#'"'"+*!'$%#%&(%*")!"'!&%$+$&$'$+*)"$&)**'(")'(*$('(+)*+%##()($$*)+#(+#!#"+#!&'('+"+""$&###"*'*+$!+*)*&(*&"&$'!%'%$
@r9569
NGNTNNANNNGCCATANNTCNTNANNGCNGGCAGGNNNNAANCNNNTNANNCNATNATATCTN
+
!!!$#"#!!!"##!!#""$!"!!$$#$#!!$$#$#"!$"#$##""""#!!"""$"#$!#"$""
@r9570
AAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTNTTTCATCTTACATTGAAGANAATGACATTGAGTTTATTACAAATGAAAGTATGTTAAACATTGGTATAAAAAAGTTAGTTAGACTTGCACAAAA
+
DH-H--5$B'DDH%HC:8/0G7@5@8#@0FA=E&(C)F3,B7!"A3D+?<,2!H;:/7>1F%B&5==>(&.)6@6"G%.D?+=%AE-1<7HCH(HBHG/:=9%0<,11!.A0B",GH>(/=B44EACB-":8F?'8/#2A;,.**H1C>G=!)A%9@H$0E<4=D8+A,46E-(7E7,?F-5,F6+F=+(503!G34
@r9571
GGCAATTCNNNCCGCANCGAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCATACCGGACTCCTCCTGCGATCCCTTCTGATACTGTCATCAGCGTTACGTCATCCTCCGTCATGTCCGCCACATCCGGGGA
+
*!%$%!&)!#!&%*$)!&!+(&*"$#+)+&))$*%*(!!('%)'*%"))!$#$%)((++%#&(!#!%()&#$$%&+(+(+$(#)"&'#&)"'+%%("%(*$+('+"%!&("(&%')"&($+'*#"#!%"%&'$!*""#$
@r9572
GAGNACCCAGCGAGCGGAGACGGGCANTCAGTACATCTTTCGTCATGGACTCCTCCACAGAGAAACAATGGCNCCGAAGGNCCATGATTACGC
+
(&)+&%#$+#($!)'%""&%#$!')")+&(**'%(!&((*"'$*$!)"+**&%&'#+$)$%%(+!)"'&#)%&*"+*+)(&'$+)#$((&&)*
@r9573
GAGTGCAGGTATNCAGATTAATCCGGCAGCGTCCGTCGTTGTTGATA
+
<;522&<<.8(&2<H7<&:%%(3#F"537*9=F9)0:;.2</E;C"7
@r9574
NGGCNNNAGNNGGTGNTNNNGNGNTCNAGTNGTNNNNNATANNNNGCCTCNANNCANNCGNNNNN
+
""!"!""$#"!"$"$$$#"$#""!###$$!!#$$""!!!#$#!!!$"!"!"!!!$"!!"""#!#!
@r9575
ATGAGTGTCTTCTGCTTGATTCCTCTGCTGGCCACGATTTTT
+
>:4):*E'('C""1CE685<:64D"+@;6(H>E5=9BB!.:.
@r9576
AGCGTGAAGCTGGTATCTCCGGCAGATTTCTGCCCCTGCCCGGTCGCAGTCCAGTCTGCATCTTCATCATCGAGATAGCTGTCGTCATAGGACTCAGCGGTCAGTTCGCCNGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACC
+
H<D6&8B48"0>+.G:94"H,D2$A<!:AEG8H*/="CH.&G,<C:B--<=.6,='G("!1:)D@E%A&3=2<F#%;!A*.##/+D8!3A./$0.?,.11@(?HA?#0G%853>@",D>(207-"42,8$@-37%,;*2?E38H5
@r9577
NAAGGTGATGTCTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCAGCAGGCGGACTTCCGACGGATTCCT
+
.>HBF7E#@2H65.<D,4-8<H'36,12,79AA487*A(?:)+.=/'A%.+$A6"'"77%:@<:G-;(80=<4B(A2'
@r9578
NCCNNGCCCGTTTAATATCCGGATGCCCAGGATGACGCCG
+
%#**%+"%"*'""&$$!$("($$)$%'*#)&#$!$+"#%(
@r9579
CATTGTATGTATTGGTTTATTGGAGTAGATGCTTGCTTTTCTGCTAGCCAGCCATAGCTCTGATATCCAAATGAAGCCATAGGCATTTGTTATTTTGGCTCTGTCAGCTGCATAACNCCAAAAAATATATT
+
4;!+.F00D(.(9B0C?:GHA(>F=,B":3B>160"B:3',2C7>A0>8HF6@-;76&&'''8-5)5(!>>$>4D%!7BE*(1(A05B5D#CGA"69%):8GD2"1F@3)(@4)'6034A!(&A;98-1,8
@r9580
TCNGCATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATGACCAAAGAGACTCAATCAACAACTGTTTCAGCCACTGCTTCGCAGNCTGACGTTACTGACGTGGTGCCCTGTCAGGTGGCTCAATCTCTTCACCGGATGACGAAAACCAGAGAATGCCATCACGGGTCCAGATCCC
+
HC)(0F.77.-!($D3E8!6H2,:5D@DBE/+)1,H/C3<?$#HH#,84CG:";1%H:"*-%D3+'@7?+*E&;;>??0E4$.&'=>:28)A"&)9B&')<>37;47>1"%E$%=?$=:%&?C+@7/14F704>=)12<1+/9-%G+)$0%6$*7&(/<D</3%!>*99H5@+<6A,%2D8'/E9=8-8+2-BG'H78,$B<)$,#@3,G-/62221=1/:+'D%F)AD4%1C7FA.8@6+>.&#F+B+DBE5:!"EC@;>'.!>)CA>%CE97*<*+A!2'/&FGEH-;!G9;B</5<C,(6%D')BA494C
@r9581
ATGGTAAAGAAATATGGCACTCNATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGNCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGGAGATATCCTCGCATGGTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAACTGCATATTCTGCATTAAAAAATCAACGCAAAAAATCGGACTTGCCTGCAAAGATGAGGAGGGATTGCAGCGTGTTTTTAATNAG
+
G(.H>E'304C6,G!,!!@",<42#%2E8(H%5B(G/';23A*-$<.(,8:<$;110$;'("#G-'9E(1;D5;-$36@&.2)+5.713D"<2#7:-4(,=A;?@01=%C?:4A<92((5="$&0**%/:"E!3-3"$..:)F!7-7D7E3-'0>C;EAC-?4#(E.86<49/"$@.1D)8,;*>;*>$;A?*C.C&6<"%#%)37$;61'H5-E*<*.A"1*AG&#>H67,;@H6%8'="%*12*EEB$*"==#+7%+&<$3B>&1E9#!A=:);'E**'AE")(60#0+&1H+D:60C>>,<1()*-@6=FA%!.(5G2.!<'.+.3-&C&CG$7@"B75'C07B42<4#2-
@r9582
CAATTCAGATCTCTCACCTACCAAACAATGCCCCCCTGCAAAAAATAAATTCATATAAAAAACATACAGATAACCATCTGCGGTGATAAATTATCTCTGGCGGTGTTGACATAAATACCACTGGCGGTGATACTGAGCACATCAGCAGGACGCACTGACCACCATGAAGGTGACGCTCTTAAAAATTAAGACCTGAAGANGGGCAGCATTCAAAGCAGAAGGCTTTGGGGTGTGTGATACGAAACGAAGCATTGGCCGTAAGTGCGATTC
+
=8A60>>FHA<.(.C6A0>?F4D77-=5F7*7,)5$DG@E&8?$<"A6<"20.3#+.E'D@B6*AA;8;(4AB:,?H(9A';1H?64H72*3'=?;058'$,CA+93.;),A.0$C+=$C2C>"<>+-3")9*)"33;5=+>H'A060#0-9A>6.,5:G?H3%7)(24)3='7"+%=5&=2G/8':D3',+2G680/-C5!HF)2,5719AB@D;>87@/D*1="E=(9(F:(-,6!4H?FC$182<%>.+2)5+2#7,DH)HDB'-#>
@r9583
AAAGATAACGCTTGTGAAAATGCTGAATTTCGCGTCGTCTTCACAGCGATGCCAGAGTCTGTAGT
+
>#!&5A73'%:=7.9GC!3+;7':,!@4G=,;,"=57E;;@8!4"4E$F8774:43+<)B1"D?.
@r9584
ATACGGCGTGAACGTGTTCCGAAAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGNATGGTAATAAAGCGATGAAACATACTGAACTCCGTGCAGCCGTACTGGATGCACTGGNG
+
'&%$+$#$'#%'"%)%%)*#+!%#)%$(&$(+*$)'"#(+)*%+"#**&)+"+&$$&!$*+()*%*%&)+)'+!#)*&&&+(('('$'%%(*"$)"*%)+'+%#&**"&&(#(!&"
@r9585
NGTCCGCTGTTACGGTCAGACGGAGCAGGAAACTCACGCCCTTCACCACCTTCGGTGTGTCCCATCGCGCCAGCAC
+
$=,C#!E:&5-&B=="-,,,*/D'E$5;?260,0""DE;4%+/%.(.'68$5@,</+'!%*%179984814?4;DC
@r9586
GTCCTGTTCGGAGGGAAGAACGCGGGATGTTCATTCTTCATCACTTTTAATTGATGTATATGCTCTCTTTTCTGACGTTAGTCTCCGACGNCAGGCTTCAATGACCCAGGCNGAGAAANTCCCGGACCCTTT
+
+'(!&("&!&'"$""+"#)(#('%&!%)"(')'$&(&"(*#*&"(+$*"'!'&*%+"*'%$)*'#$)$&*""$***+*+(%&*(($+#)'&$)(%**!$+)($"(*%&'#""'++"%)#%&(&*+(%')!!(
@r9587
NTGTTTTCAACNGTGATGAGGCATCGTGGCATCTCGTTGAAGACCAT
+
#1'&8#,&F3=?8DE>EF:!292+(FC-/5%B5CHCD#):%5(1,7C
@r9588
TTTGCTACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATG
+
G!(+<1,3CAB#281A0+1@8>9@F":<;H*>D:(%!B8';2+G#!(@<<68F))+D>0=,*5/6'0EAB.;F$9-69
@r9589
GCCGCAGCGCCNGTCCGGCTGTGAGGCGCAAAAGTACCGCACC
+
&0G7?/=/$F0F5A49H3>E<DCFA@;*A+08%51$@G$5,E9
@r9590
CCCATTCAAGAACAGAAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCGACTTATCAACGCCCACAGCTN
+
,.'&1H2EGB:$!&=.>''62A$!@C+<G)/BA)G+D:%476?,G)HE=&$?GG2;*C7EC/A..,B5-B>*3),6FEH$,3C#6A9>CC
@r9591
CATTACCGGACAACTGCNGCGGCACCTCAACTCCGATTTAATGAACGCAATATTCACAAGCAATGCGTGGTGTGCAACCAGCACAAAAGCGGAAATCTCGTTCCGTA
+
)F6G2:.E,FH/2B,4$*;C!B:G)/9%+25*069@2504F71"3=>F<=<;:AG.+E4$C))0C=9"+)$;<.>F?"F<H9='EED0!!*&G$,1@AA","8#(+4
@r9592
CGTATGTAATAGAGAGTAACTTAAAAGAGAGATCCTGTGTTGCCGCCAAATAAATTGCGGTT
+
2('-20'"C,"'A8'32F@?+A4#HAC)BA#!:1=+354..GG@)A3:7,>E;"/&:7;(G7
@r9593
CACCGTTGATGATCTGCGCTANCTGNTGTACCTGCGGCTTTTCGTCGTACTGTTCCGGCATGTTGTTGGCGATCCGACGCATCTGCTCACGGTCNAAGTTAACCATCTGTGCGGCGATGTTTTTCATAGATCCACCCCGTAAATCCAGTCTGTGTTTGTCAGGTCGAGTTTTGGTTTGCTGGCTGTCACGCCTGCCTGTTTCTTGTTACGGTTGATTTCGAGNTTGGTCCACTTA
+
!+9?7E4H*E6!:!809?6B1$$.C:EF*23<$/-FH?"3.6FF*H/$&/*2A+?.?'!*D)G(:0"&F41C*%&>5BGC2#"B*;#<853E5#+'/)<A&GG'"C;>?,'A<?.<BB1=G#9F+96@@+)5B(:(<$D%2A-3*E#9(2>#3HHGH>C=6+C-3(D./;DA+)B33+6AE'BAE';2A;4F:E=+!/<@!!;0/8!/;HAD)'@/)D1=(,HH(>"-#G93'"(
@r9594
NGGAAAACNNNATAANCACGATGGAACAGGTTAACGCAGGAATGCGCGTAGCCCGTCGGCAGAATCAACCATTTCTGCCATCACCCGGGCAGTTTGTTGCATNGTGCCGGGAAAAAGCA
+
#'*'%*#&%""%&!""(+)#"%&(+(('%"!#'((!%*'++(*$*"''))&$!%$'#+*"*)""+'+%'&%$"*#'(!"*#!+*$(&#)&*!%!%)%"(#'$%%%!"&"&)("!*%&"&
@r9595
CCATCCTCTTCCTGCAGGCTCGCCAGCAGCGCACTGAGATCCAGCTGCCAGCGGGAAATACTGATGCGCAGCGCCGCCAGCGCATAAACGAAGCAGTCGAGTGCCTCATTGCGTCGCTTTTTGCTGTCCCACAGTATTTTTTTCCTGC
+
G=&.&4;!H>A:;'0;)1"H,(6@C;'?./1A5%6;7;7"8=G!H%*#":BE(><H'.$:>8;F8,6B)32A&C&&'.;(1&AG/E:9@;-0C0/83)'20E!-DC4587'6-);9#(6D3;;;!-G>,-B07?H1E!!%)G"(64D<
@r9596
TNNTANNNTGGNCNTCTATGNTATNCTCAGNAANTTAAGCGATGGTTTTAAACATAACCTTCTNAAAGCTATTCAGG
+
&'""("'#'"($"#!'&*%)&)%%!)&(**&'#(%*$"+'"'("&+)$$#($("*%++")!"%(''%"%$##$!#!'
@r9597
CTAGATTACCTGCTGATGATCAACTGGNTTTCCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTNCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGC
+
'"*%#%*+'"$!)*&*+))("(#&)$!)('%)#("%*(+)*'(%+#(#+*!'&$!#!#+)&!#($&*"$*&"!%()$(*#)*+"%&&#+(%+!'"(&%)%+!!+#!+'%&""+*%%*&%)!"#!$#$)%!+!)(
@r9598
CCACCGGTNCTGATACCGGCATAGTCATCATCGCAGATTTCAATAACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACGCTGAAATCCACGGTCTG
+
DC6?!<,H"&)%0?25'&5C+'!#<?E,#4BE"&"5?1921)G9C8B*,'!F&H60B(;BB="$5>46ED:!E-+*G?./3&78CF3/E0=:/=5$,<;75
@r9599
AAATTGATGGCAGCAAATACCGAAATATTTGGGTAGTTGGCGATCTGCACGGATGCTACACGAACCTGATGAACAAACTGGATACGATTGGATTCGACAACAAAAAAGACCTGCTTATCTCGGTGGGCGATTTGGTTGATCGGGGTGCAGAGAACGTTGAATGCCTGGAA
+
>,)0G@'+59'.9)".-8BA"3G62@E75C+!$A/-*#6D".355'BDE,?HC:1$7/9-":;C$(,50,B"$C12!-+,'!4$:3F:?A0>==BA$?+54(:DF@#47&;,86<1'-A.#:<E@#@4?C<.<"D/EF7(=6@,7%+?(G?-'?*>+@0>4#;#?+(;:<
@r9600
GATCTGGTACGCAATAACGGCTATGCCGCCAACGCCATCCAGCTGCATCAGGATCATATCGTCGGGTCTTTTTTCCGGCTCAGTCATCGCCCAAGCTGGCGCTATCTGGGCATCGGGGAGGAAGAAGCCCGTGCCTTTTCCCGCGAGGTTGAAGCGGCATGGAAAGAGTTTGCCGAGG
+
=B<D*14H)B9,HC8<'1(4@F<$=.<3!1)B?;G#/55/850(&0A!HD(H689B-7$=/2>054>":6%,%075%#64*='2H!'.!#G+'22+D9"BF:%5>;.-$C((*>13:.%<G'5B7$A>*58)?%H6HA$,2&4(F->!:/GH)=C,A1E(%CD,9233F95"-0D/39
@r9601
ANACANTTNAANCNTTCTNTNNTTNNCNAANNGNNGGGNNANNANNTNTGC
+
!$$"!""###$!#!#$"!#"$"##!##$#$!!#$""""#"$$##!!#""$"
@r9602
AAATAACCCCGNTCTTACACATTCCAGCCCTGAAAATCAAATTAAACCACACCTATGGTGTATG
+
+%>.)9E0E6/.A';><-:-/@;/(><B7FG/!H'<,+5:,/;B#3;HH(/A6,20&/;E"!3A
@r9603
NGNCTTGGGNCCCCATCCCCATCTTGTCTGCNACAGATTC
+
!("'(%#!!('+&*!"&')&(#!*)*#'!!'('*%))$'$
@r9604
TCGGCGGGATGNTCCCCATGTTCAGGGGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGACGGCAGATCGTATGCTGGTCCTGTCCAG
+
57$'A=@-0)F<!H6G<9F"74>:-?+%!8?=H#3H"0F$+?><;3>:9<,"FH>9C)5+B@?:.*=6*#8;6B:H973F7<!12+1E--3G5C.@'083B1=<$=$1&C<AE0G!-7.%H8>G50D6)7;FF0F&+0.&9&:/0>?#?;H198"C@FG'=/C,'D'B8'BH)9,!63/+3&0?#)%+79+#13&F:B>5:>0=5
@r9605
AGCGAATCAGCAACTCACAAAACGGGATCGTGAAAGAAATCAAAGGCGCGGACACGTTCATCTTTGGTCATACGCCAGCCGTGAAACCACTCAAGTTTGCCAACCAA
+
A>(B;D5*542:!6(375=!DA&7G(*2:3">)F7$!D6>H69;9B12&913F1'2*!55B8;(.5$?C<1107;#@!=&C<D/23(46FE,)!!(>.H:?7F"--B
@r9606
TCCGCGCTACGGCATGGGGAAACGTCTTGGTGCGGCGGATG
+
'$-0?6)>D02GG-5&3G,F/+&!$#-'7&'D3H.3,&43$
@r9607
GGACTNTAGCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAAAGAGNTTCTTTGAGTAATCACTTCACTCAAGTGCTTCCCTGCCTCCAAACGAT
+
!2-6D9,$(<<*B'->@%D;3G5C2??/?:+DE.ED$A!&-3<*"9-"-<1*9+B"@"<G=D/4H5=A0;+!6D(EC5C4:B!'9,7:E156?D*62!%0%F+"E;:&*'
@r9608
AGAGCAAAAGTGCGGCAGAAGCGGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCGC
+
H58E>#D@2HH73>5&;4%CGBH4-80?EB+,(,*3D6F3-6B>H6%;=G-;./<-9;#9@<../?-..3',H3)B*(#562
@r9609
TCTGTGTCTGAATTTCATCACGGGCACCCTTGCGGGCCATGTCATACACCGCCTTCAGAGCAG
+
A'?91B;!5?9;2E*73#&H!"9GD41.3F)C*/FHG21,'HF7$',.:<+-&D6;G=$(+-:
@r9610
AGACGTAATGAACCACAGATTCAAGTGGACGATGATAAATTCACTAAANTGTTTTATGACAATATCCAGTAATATCTGCTTCGAATGAGCTCTGGACATGCAATT
+
E')4%3G3C=E!#@>GA)74<1/411&-)6<-!B#!0&>65F4-"),3@G2,((06>&$6'0B7882A.G*=8<<$!=@:(51-E/E-5C;"C&-3.!"7)5!CE
@r9611
TCAAACACAGACTGGATTTACGGGGTGGATCTATGAAAAACATCGCCGCACAGATGGTTAACTTTGACCGTGAGCAGNTGCGTCGGA
+
">$#0E=H)@+*D)EA?64B/%$6"6BE10F52/2"<'01!$A83B/EH8+.7+4'HF=-5$*.>0*%?!,=C50E.9A#*?A363(
@r9612
GACAGACTCCAGCCAGAACTGTTCATCCTTAAACCACTTGTGTGGGCATGAGCACCCGCGGCCCCTGTTGAACCGCTCAGACTGTGAGCATGAGCCCCC
+
"($!+&%'!(*&'(!!""+$*"%)$&*#((*)%%"$%%!$$&&(&+)*")!&+"!'%'$$$+#%%*$$'%)'(%((!%%!$*!)&&&)*$%"'"!*'$#
@r9613
NTTTCTGCCAGCACGCGTGCCTGTTCTTCGNGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCTGTTTTCTGCCGCAACCGCTGCGGTGATCTGCGCGTTCAAGTCCGGCTGCGCCGCGC
+
#)'+"'*)''&%")&()'+$#()*'%!&'$&&"()&*++#*%!#"(%&#$#%#$&%"($$(*$&#'*()%$+!+##&"")(*#("!&#*##"#&)+'%!%%$)"'**"'&%&&'#!"'%"!*&#)*(*&(
@r9614
ATGTTCAATTCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTNTCGTTTGGAGGCAGGGA
+
$:)F37%-*!@)0:7,#3$..+(*9/+=#,'%C?#'!%?#7B+-/0+=44*7!B3"E4?"E$9F."5F<C,G($'<&5*3$G?E1?,B2"C3B/2(!@8)C?
@r9615
GTTNACNNNGNTCTCNGGCNATNNTTGCNTNCGGTCGTATTGCC
+
%*'$%)!!"#!&(##"(()#"#""#'%'%##%#)+!'!!+#"))
@r9616
GGCGCAATCACAAGNCGGATTCGGTATGGCTGCATTCTGCGGTAAGCACGAAC
+
?03%!:HGB%-6/B)B-/*7*D-FC'4<7A8;:B*4AF;@5.E@"?3%;3647
@r9617
TCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCCCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGCGTGACGCTTTCTGTCCCCCGTGAGGAGNCTACGGTA
+
1,E"H<!<95!$*7;C8-'?3/>@!)13#?C?E9::D7>(FG";*'=H8A3H4+0,2=GG::/#@&F.>3!!#>!--(%,<7F.HD7C8+-74&2%";G933;'7/<+,H5;>7;2>
@r9618
GNCCGTNTTCCTGCTGAGGTGTCATTGAACAAGTCCCATGTCGGCAAGCATANGCACACA
+
*%&*(*&!*#$$(*&&*+)$()&)*%""'(#)$"'%)+!%($#&$'*!#%!)&%*)()(+
@r9619
ACTTCCTGCCGGACNACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCAGGATGCGGACGCACAGCGCGAAGGCATTAACGCCTCTGCCCGTTACCCGAAAAACTGGGTGACCACCGGCGATCCGGCGCGTGAGTTCACCATGATTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGC
+
0<(<!?"C$9#E!>=85,*+#"(:'*;=73&.36)D7H7&&@1#4?8*?G&;&&+#%1)2-!>9%%5*40,>72D79+=7(A;<D%:1F/*?&>8!/G8HH0E<.26/&D.F:-4/H($7"#BGA)277)6C9'%<&!19;/+7E*1(B97%HD:*+3++%/06B4"1D,8'!1*C#B3GBB*C*!'-/B'&=!4,?9$7-F&6$>B6+#.FF%(%&%>)/(?)3@8.#05'($G:86-6
@r9620
NCCGTGGTGTGCAACCAGCACAAANGCGGAAATCTCGTTCCGTATCGCGTCGAACTGATTAGCCGCATCGGGCAGGAAGCAGTAGACGAAATCGAATCAAACCANAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTAAGGCCGCNTGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATC
+
$(:$"FB)H/":;7"+72BC-)DC(3=8AG)92F907.F=6@==8B5;:0:9?>3E'';>4G#)36;5:8)4*:;(<>>7$8E3@C-*"4@%FG@>AE$.7$8+A.'D6;G%%"BAC+?*C003;85DB(&9=A5+7&C&A)C7<A77B#3+7(0);7AC4H@058E+&(HB0-A4B:.(A&@<1D@356@$,=?69%HE-93:(BD/.!@F'!$5>$=73A!=*.@E0&,@('=!E97G$A"!1%DE&=$B>0+
@r9621
CANNTCATGGANGNANNNCGCACNNGTTNACGACGCCTGCGGCGCGAAAGGACAACCCGCGCATTACCCAGCTTGATTACGGGCAAATCCCCCCGGTTAACTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTTTCA
+
*'$(%$(!'**"#!")!&#'"%&#%&%)"+'+"(*+"&$("#**!%!('!&$"#&")#%*"$+$+((%'%(&'+(*')$*&""))'(()#+"&$"%+%#)"%$%)"%#'%+$!"''"(!%"")+&""$'%&&#)(("$*"")
@r9622
TCTCTGTTCATTATCATCGCTTTTAAAACGGTTCGACCTTCTAATCCTATCTGACCATTATAATTTTTTAGAATGGTTTCATAAGAAAGCTNTGAATCAACGGACTGCGATAATAAGTGGTGGTATCCAGAATT
+
C<$8G4.B46#3'%(/H&=@!C0'9&A+!A3*A%+?/03%)<;&@FH12,"G9CF9:H+#8"-D:%*B19&)A4!7:?&H;+*!F6)460"-F%-+!:@#.+C4:D7:?393:H'=6%)2=3/+F9E#5<;C34
@r9623
AATACGCGNAGTCATACGGATAGTCCTGGNATTGTTCCATCACATCCT
+
#)$$*$)("""+&%(%"!+'"+*%)&+)*"#+#$(+%"#%$+!*%+)+
@r9624
CGTTTCGTGTCTCTGCCGGTGTGGCAGCCGAAATGACAGAGCGCGGCCTGGCCANAA
+
7(A.?622'8?FH4'"F%9"<7B5'G.*0EG3!?@,>BG)'A7E:>H;$*H<6D79'
@r9625
CCGGACATTACCGGACAACTGCTGCGGCACCTCAACTCCGATTTAATGAACGCAANAT
+
5??523CG)"5123HE/C#;-1G$=1C4?!')266D>!C)<%-4$?E+HA)@@<E7/"
@r9626
TTGGTCAATCACCTTGTTTTCCTCNCACGACGTCTTAGCCACCGGAT
+
)!432AH1(8,%&F-A;:-(,A*F8.0-GA9<72?@!F8."@69HF3
@r9627
AAACTACCGTGAAAAGTCGGTGGATGTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACA
+
2/1F,7+75D178%()0"D>@D)5"D!)H<<.?1?"#$0;63=3'638C=D'8C"72:*741>G&?"D@H>)
@r9628
NNTTCTCCGNANNNNCANTGTNGNANNNNCANTTGNGNNNCGNNATTNNGNCGTGCTNCNNCGNN
+
$!"$####$$"$#"!!##"#$$!"#$$$"$$$##!"#"#""""##!#$!"$####$$$!#$"!#"
@r9629
AGGCTTTGGCTTTAGCCGCTTNGGTTCATCAGCTCTGATGCCAATCCACGTGGTGTAATTCCCTCGCCCGAAATGGTCATCACAGTATTTGGTG
+
B@7:'BF#+1?/1&2,#A",90;+.AD7=%/%D,=D.$98B3$F?G8.0>/3C)=!FA$?>@)*HC4@>3$<C6:#*:4<=!3H2)HG)2B1G=
@r9630
GCAACCTTTTTAAGTCCTTTTATTAACACGGTGTTATCGTTTTCTAACACGATGTGAATATTATCTGTG
+
',=<1*%"86&E"0-!C'$.8<7E2A<)3/1C39D)+#H*1,2BD;9?$G2.B,.9>2!,72:$,"7,4
@r9631
AAGCATTTGCTATCTCCTTTTCCGCCACTACATTCCTGGTGTTTCTTTTTCAGCTCATAGAGATGGTCTTGGGGCGACATTGTCATCATATGCAGGAACCATGATTGCAATCCTGATTGCTGCCTTGACGTTTCTAATCGGAAGCAGAACGCGCCGACTGGCCAAGATTAGAG
+
0!!"5?7;5'0".--(01.8-*&D7<4G=HBE;>A:",F)$.GD":B(8/-)DC>&A5714,=3&"2?'/B*'%;1*4<9@FA('$&BH.&8?(<,7(E)=?*)$:*;"A30<B7F#7#DGG)!-)';;)F5DG/>':'EEH('40D!=.5GH.003!3D@-@!4!>#D&,@<
@r9632
TTTAGCTACGCTTTCGAGTCTCATGCGCCTTCTCCCTGTACCTGAAT
+
G,2*5&04$C3??7)-9-0=*'"9'095#?@$A9>B9&<".HF?-4>
@r9633
NCAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATA
+
!D/7=("'*3*).7DG>#8"%A;#?<59D9>D57*#>H4@.9$)<D&9=@)1-:)%G4@7%2'<9.
@r9634
ACGNCAGCGTCTGCCCGTTCCATACCGGCATACAGCGCATCG
+
:(B.%#FGG?=B?"%#:0(A8%=;:<?#G144:-;/6!@A-/
@r9635
AATGGGTGTGGTAAAACAACAATTTTGAATGGAATGATTGGTGCAATNACCAACCCAGAAAACAATGAATATTTTTTNTCTGAAAATAATANACTTATCGAGTCAAGAATCNCAAAGGGATATTTTCGATCGCTTNTTTCAGTTTCGTTTAGT
+
,AF-!<&4B.#6:4'%4!G-/B9?5;&8H%&<-961G=1!&:)F>1B1,"!-&('1%-;#C&)()"A(HF5'8)@=76$=@!C4,(D8F*1.FE7,%7F,(>?!54<!3>#;F)+5)@@D3<"2<6B0!<$';6(@+GEB<@974)3691"7#
@r9636
CAGCTTGGGCGATGACTGAGCCGGAAAAAAGNCCCNACGATATGATCCTGATGCAGNTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCGTCTGCGCGGGCATTGCCACGGGTAAAGTTGGGCAACAGGGCTGCATCCACACNTTCACTCGGTGGGTTNCACGACCGCAACTGCCCTCCAAATCCGCTGCCACCGCCGTGATAACCGGCATATTCGCGCAGCGATGTCATGCCGTCNGGCCCCAGAAGGGTGAGAATGGTGGGCGTTTTCATACATAAAATCCTGCAGGTCCCCTGCGTCGCTGTGTC
+
,D$&C#D55;&*?F=;+EG?2#:F$"%/HF905/.)A?;%2A<F)=1G#=H(,0E.H;:0'>?1=5&!AE@E-:61FG8)0A9>3&5D"#3BH7B@?-)?7HE"+)C?H+=@-G5H&/6D-:B-#8(9E8+0)<F5.+$66+-;4-!!5@G;:/..+7+!D4:=+?H'5@#DE5>B?%F:*"2AB;7=#E/<;A'>+C.*:&FGBC=--#=#A89+%48,0/&<?*H:4:'!@;D%6:+5"3H(-6)<&G:64EH1)98A/7,0>D+.#*+.2A,6#'E$+$7E.&%H!$E2#BC)A3F*.779635:>%62<D/B$
@r9637
GANTAGCCGACATTGAAAATGAAAGCGTCCTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCA
+
135.&@);=&<?-?(H8B"@2?=?7DFECG)D=?.5!8<B78:-/FH)!?'"C6#+9<#0D<DA=F;BHA@6>
@r9638
CCCAGCACCTGTTTGAATCGCTATGCATCGATCATTTGCAACGCCACGGGGCCAGCAAAAAATCCATTACCCGTGCGTTTGATGACGATGGTTTCAGGAGCGCATGG
+
62?*"<,=!.@*$>F?0;*@/,9;4,0F'=H#2G&)3=7$@!E0@6DF=@=AD0<5&038.?D&?*0"0?#C4&?@(2E..?'C<#(8F#F*F.<7"3@968-D7A7
@r9639
TTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCNATTACTGATAGAACAAATCCAGGCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACG
+
@D)%=!E9B%8B4;'C3!"*>5D3-A-!2@D=1?=7@*(22CG<9>2F3$D?0-7?'5::3"!:9C<E7;B$591>%<8"9HEF-!5/4162F)&/$1%E*8=BGAH<GD&'26&,.%9BEH%.>=@9505+@4!D;E$+,%
@r9640
TTGCCCGTGCATATCGGTCACGTACAAATCTGATTACTAAACACAGTAGCCTGGAGTTGTTCTATCAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAAC
+
*)F&-&C'5:D("'B35C;AE+.;&$;,'-E2;$=D"<%?.7-4<@&/"5/6%G;$CCA!B3'H2A;&76""977+622G.40C/!7:3A44!4'!H7C:-E.>(H&0C"8&BD#(:F9>:/86$$F"(!!D(!9!A%""5
@r9641
TNCGTNTTGAGTTCAGCGCAGAGTTTGAACAGGTGGTGAACTGATGGAGGATATCCGGCAGGNANCACTGAATGAATGCACCCGT
+
&!(""#&+*'(&!'#()#$&'$'$*"#(&%'&*+'%%%)#++%"'%"""%#(%)$(!'#%**'#*(#!'"'!"'+"$)&&"')*&
@r9642
CGNGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTT
+
*!+%($"*$)####)!#%"&$&$+&%+'$)"%!!&$*+%*#())#%+*(*"$+)#+&+(!*%%)#&'&
@r9643
GGTTGCTGATGCGCTTCGGGCTGACCATCCGGAACTGTGTCCGGAAAAGCCGCGACGAACNGGTATCCCAGGTGGCCTGAACGAACNGTTCACCGTTAAAGGCGTGCATGGCCACACCTTCCCGAATCATCATGGTAAACGTGCGTTTTCGCTCANCGTCAATGCAGCAGCAGTCATCCTCG
+
H?"E72?*G?*8%'73.D#31!(/#*417-'>:*'4,C,26*</,2-"E;A;F+%A8,8H<F7=/+A32?)<F;E8?@6%::28>+H=F-B'BB''=#F)'1>58/$6@G$+>;A(7?#8)EA%0"E5<=C"-'::.A!!*D/H%E=B:"@)>6&'49F?BB0C8$&%?D-D?$=)DF=:G@
@r9644
ATGAGTGGCGGCAGATAAAGGTGACCTGCGCAAAATGGTCGTCGCGGGTCAGTAT
+
..55?#BD)71D#/6AG&4E3&F7,91@/0=8H.5>730G0"<.=F<%07$426<
@r9645
TCAGGCTCCCTNTGANGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGGCGTCGGGGGGAGGCTGCATTATCCACGCCGGAGGCGGTGGTGGNTTCACGCACTGACTGACATAC
+
*'*'"$)&!#*$#*&))+'!()$!*%!&(*+%)$+)"#'%#!+*#&')+!(#)('%')*'($*"#+##*"*$!'#%''*'**!!+*($!&"!$+!$'!+%"%#*(()%*&(+%"+#
@r9646
CCGGCGTNGCGGCACTACGGCAATAATCCGCATAAGCGAATG
+
A&(B6*16/1'BE4,%$%</:?0C3E+!D(,*3H36=@,;?B
@r9647
AGGCACTGGCTGAAATTGGTTTTGTATTTGGGGAGCAATGGC
+
),G'$)?:=/'AG+0+5G26-H2"<-*,47ED>6F&11"$6;
@r9648
TATATCAGCANCTAGCATGCAACCTATCAAAATGGANAGTTTTATGACGAAAAAACCAT
+
E5%,:H@(*(>$;>+H=+5':=E'$,;'43C'E;5F1")2&,=?H*:4;?-B$"/B=1'
@r9649
TTTCCACCAGTGCCTGTACACCGNAGGTAAAGCGCAGACGG
+
AA6-@A$%=2<!+D:).345!-;-@#+A9D!:=H!9<:A7F
@r9650
AAGAGCTGGGCTATGCGCTGCAGCATCAACTGAGGATGGTAATAAAGCGATGAAACAT
+
=H)*E?'B"<+57"/@G87;43''.28B:=E6C1)&7GE(F,(0!006'2:@H:10HD
@r9651
CGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTTAGATAACAATTGATTGAATGTATGCAAATAAATGCATACACCAT
+
-**:++G"D#@B:D=<B;6.'438?-&//0407.#F9=+%A29F4=*:1GF"EFE*FD8'#/223&A%)5$C'=.;#-F,H2/6.<EBE6'=":;
@r9652
TCGTCAGCCTCGCGCCGGTTCAGCAGACTGAAATCCAGCGGATGCATATCCGGATCGCTGAAAAACNGGCTGATCACGGTGTACGTCAGCCCGGAAAAGTGCATATCCAGCAG
+
2>#C5E*-$2=@.5@>07=4$'+/.)4<$@()4;04?+@.H=?$-3;54.CD22.)+#9>.7=;<08#(%@9%G,<;F4<8;A=#0$6<@ADD4:2$=!B<:;$E-@>/F6?@
@r9653
TTCTTTAATCTCGATTACGACAAAGAAATTCTGGCTTAAGCTCTTGC
+
=:7%#7>F11C9G@?+?@E*5>*?(*EF=#*G39'(*..-"('F?AH
@r9654
TGTTGGCCTGTATAGCTNCAGTGATTGCGATTAGCCTGTCTCTGCCTAATCCAAACTCTTTACNCGTCCTTGGGTCCCTGNAGCAGTNATATCCANTGTTTCTTATATAAAGGTTAGGGGGTAAATCCCGGCGCTTATGACTTC
+
":=2+#F!F'2G%:020'AB6";.@E3A&C/):.3:((D?*1BD:-@@DG9,:5#@?2(+<#/=5HE/A'A$$#3#$D?"1A=E4"8?EG+<A!="D:&<3HG3B7=G1F@-'D*D#60.F4'8@+B#<A8!!10ED=G(86.B
@r9655
TCACCTCCGGCNACGGANCGNCGTAACTGTTTCCGTTGACGAAGTTCACCGCATCCAGAAAACGGGCGTAAACCTTACGCCGGACCACCGTTCCGCCGACCAGANTCTGCATATCTTCC
+
%)*''%')"(*"!&#"*&*&&*+*)#$%#("*%"!(*+%*$#!%$+#'("%$'("(('+&*&'(%)$((#+&(#'#+"&+&+*"'#&!$*("%+**$)(*")"#*#%"+'(+%&#"%*&
@r9656
TTATCGAAGGTAAGGTCTGGCGAACGGTGTATTACCGGTTTGCTACCAGGGAAGAACGGGAAGGAAAGATNAGCACGAACCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAAA
+
*/:&D5AB($6-)0?)%C(7-&31GC4(=GG'==70*C7C*)A529H2=1306+3,"-CA.F7H?"%'<+)'C%=B79(8@<-$A<A0H7H&A0G7D!D:E,.8%A5+"A/.82>G!<@
@r9657
GNATCCCCCAATTTGAGGGATGTTTTATCCCTCGTTTTAGGGGATTTTCCCTCGTTTTGAGGGATGCACCATTCTGAGATGTTTTTATTTGGTCCAAACATGCCGCCTTGCTGCTTGATAATATTCATTCTGACGAGTTCTAACTTGGCTTCATTGCACCGTTTGACAGGTAACTTTGTAATCTCGCTAAGTTGAGAATCGGTGATTCTGTCCATTGGTTTNTTCCACCCATAGGTTTTACGCAGAATGGCAAGCAGCACTTTAAACTGTCGCTTG
+
%%75)"860*"!=F+@H2E)$738C*E:>2-!/F6(@#4!BGB$=7DD*B4*?DA,(H'.D($AD;2+H)G+!?C4H?0/D=$>/6#3D:>>,+03BA401$9*6B53=?014DF&*B9C717#.GBBG:29002#.%."=,(;;)@"1DH<1<?#';6569F.4981C,2"2!$E&5";6%&H#8A5-!72@>)<1<F#;(&AB@=;,D2*0E=>))E%31C/1F2<=8742$??24"9!GD+,>8G=&%G>&"7052F8$FD%.29=1<B.<>2
@r9658
GCGGTATCAGCATCGCAGAGCAAAAGTGCGGCAGAAGCNGCGGCAATACGTGCAAAAAATTCGGCAAAACGTGCAGAAGATATAGCTTCAGCTGTCNCGCT
+
$6D+@A?@=)G'&,1664#D:>+?68-/4)!#%H3E4'EC<-3C/8@8C+;;1-F<6#$.0'3%-@C6?2&@-,!D2FHA"G2C?<3A-GB6-7.<:)>6%
@r9659
NACTCAATGCTCTTACTTGTTNTGCGGATATAAAAAATCCCGAAACCGTTATGCAGGCTCTAACTATTACCTGCGAACTGTTTCGGGCTTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACAACGAGNGAATTAACCCATCGTTGAGTCAAATTTACCCAATTTTATTCAATAAGTCNATATCATGCCGTTAANATGTTGCCATCCGTGGCAATCATGCTGCTAACGTGTGACNGCATTNAAAATGTTGTCTGCGA
+
+*!+%'"!&)$(&)*!#*&"('&#++!+$%"&#'+'#'*$&'$%#'&"()#'$&#*+($$$($"+*%&*&+#*&)+(()*$$##+%&("((&"'()&$$!')&(!#("&*!#+'"'+)%(*'#)!$%$%&"*!*"!!&%(*&++&()#$*%"'*$#'+*'((*)'")'+"+'""*'!!+#*+)+&*()"%+!)"&'+"%#+)*%!'!**'+'((!&&"(*&#"+&('+&'!#%!%!))#$!%)'+"$%+)+)!)"$+"&#"%#%#%&(#(&#!)!'%&$"')+#)#+%&#&#')'%'(#%#'(&&$$%&'"%!)&*+)(&'$%$(()$'+($'+
@r9660
GCTGGGTGAAACCCGGTATGGATTGGCTTCGGTCCCTTCTGTAAGAAAGGTGCGCTTTGGTGATGGCTATTCTCAGCGAGCGCCTGCCGGGCTGAATGCCAACCTGAAAACGTACAGC
+
B7%C5HA+-1$-:07/8BA7&$*#?':)-%.0$-68C;-GC:&B2=,+C#6.*8(G8!:87G-2#:A=?@CBH*6:0D&>5H!<5.G+C!A>78CG&'A>;-+-)-)+2<164+**DB
@r9661
NNAATGCGCCGCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAACGAAGACGCCTGGTCGTTCAGGGTTGTCGGACTTGTGCAAGTTGCCAGGAGAATCTGGAACTTATCAGTAAACAGAGAGGTTCGAAGTGAGCGAAATTAACTCTCAGGCACTGCGTGAAGCGGCAGAGCAGGCAATGCATGA
+
##7*+H0$G;@1.)4A9A0F2H#>02.)#+9D":2$&)$C7G#!?42A=#?G9()::*D3,-*<'66=<<%F-&#C@2=6:%4-G/B8GF$C.#=;&E5$./:?#,.491)-+'/9"0#7@.$'G"E>1H&"?/@#%&+8EC%#DH;&4,E14!9%.*(HF'<>1'/H!!=?*+GE'*)"<%8>,F,="=/*.ED+-B'F(805!.(9@E":#*
@r9662
NNNANANTGANCTGTCAAACNGGNCNNTGACACCAAGTTNGAACTGGTCAGTATANNTATTATCAAGCAGCAAGGCGGCATGTTTGGACCAAATAAAAACATCTCAGAATGGTGCATCCCTCAAAACGAGGGAAAATCCCCTAAAACGAGGGATAAAACATCCCTCAAATTGGGGGATTGCTATCCCNCAAAACAGGGGGACACA
+
$"!)*&$&"*#%#"')*#)!"&#%$""*'*#$'(!(&$)"*$$*)")%%"(##!'"$+$*!!'#!*')"%(&)""%(%(!"(&##$*''"#"$#'*)'(*#$(!'&*%"+&#*+%&+')'')$)!(%#++#!)')()*%!#)")*())+)'+%!+$!$++''(%&''%%"%*%*$'$$*!)$!#$)!#($%!"%#+')!%$#"+$
@r9663
AAAACAGGAAAGGGGGTTAGTGAATGCTTTTGCTTGATCTCAGTTTCAGTATTAATATCCATTTT
+
D$04=HF!3D,C:':60/<<9.":*,-0*C5:/'8;&/<A%?BB@/#.;49*F?81%F?!-0@4;
@r9664
CTTCTAAGTGACGGCTGCATACTAACCGCTTCATACATCTCGTAGATTTCTCTGGCGATTGAAGGGCTANATTCTTCAACGCTANCTTTGAGAATTTTTGCAAGCAATGCGGCGTTATAAGCATTTAATGCATTGATGCCATT
+
$*)%'+'"%*#""**)(&$$&!&)%&++*$*''$&("#")'"%$#'$(+)+$!+%%++'"+''*#'+*!#$*()#"))!$!)&#"&(&)(!*($()#*&!&'%(*''")(!%(#%)!!))&+&$'*")%"#$$*#%"("+#'(
@r9665
GTNTAANGGCATCGTTCCGGTGGTGGGCTTTGATGGCTGGTCCAGCATCATCAATGAAAACCANCAGTTTGATGGTATGGACTTTGAGCAGGACAATGAATCCTGTACATGCNGGATTTACCGCAAGGACCGTAATCATCCGATCTGCGTTACCGAATGGATGGATGAATGCCGCCGCGAACCATTCAAAACTCGCGAAGGCAGAGAAATCACGGGG
+
(#"!+*&"!++!)&)!%+!($$%#+&$(#*!")*"""&)&"'#+%$#'%!+"%&!#+&%*+($&+#%#+$""*$*#!$"(%+))'"&%!))&&$+((!&%$(&+*''*'!$&*)+''&&")#&$'*'###&&+"*#$&*$&+$'++$*"%+*')"&%)(*"$("*+**'+)"))(($(%%&+#(!$$"'$&(((++(!'(%%((!!#&+(*"#+*')
@r9666
CAGCCGGACGCGGGCGCTGCAGCCGTACTCGGGGATGACCGGTTACAACGGCATTATCGCCCGTCTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCATTCTGCTCGATATGGACACGCCCGGCGGGATGGTGGCGGGGGCATTTGACTGCGCTGAC
+
/D3-0""5??-%>=CC,',%5B)5B<;>5F#(3A6!26),?7@;:E4/!,H9+H8'@-(8?7)!D:6(7;4$%87'5+$2*E7$,6BBF<)@EE#!'-/D4%F<B$&F)B#:;>?,5C:CB1)5#%#3G$3?;HA=2*FHF?D.*/4A"AG80?#3DEC-
@r9667
CACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGCG
+
.E@#E;:E6)F(BFBHHBB7G&158<051*G,/A8=5&!H9E4:B***@E((FB2!93A6H,*()+8,810-6=*2&$2:'A(70&?(@291<$-*,H?>6&'
@r9668
GTCGCTGGTCTGGTTAAACGTCAGCCCTGCCGCCTGCCCGGCTCTGGACNGGACCAGCATACGATCTGCCGTCAGTC
+
#(+!%#"+*'+)!+'$#&+%%+(!"'($"(*#(+&'*')'&'%'""#*#!)""*)%+*)$!+&+%)%!!*%!(#*!(
@r9669
ANCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTG
+
&*B9<+*G2*D*-CC2%,>)GEH>"%=&"-1@D+>47HF)$49%2)'H,67%918BB@(""2(9$';@'B1;AB
@r9670
CGCCGCAGCGCCGGTCCGGCTGGGAGGCNCAAAAGTACCGCACCTGCTGCCGGGTGCCTCACTGAAC
+
;+?57-@4&C)$-B65+1,A+;A;=A5?F!F>!*6906(4;&6$)/+&F1(EGF<;*H&EC5B."!/
@r9671
CCAGAAGTATATTAATGAGCAGTGCAGATAGAGTTGCCCATATCGANGGGCAACGCATGCAA
+
=G!*(2B@2.++3&<;6<5><$C1%3(98H#./1$7A&;F.!7?>2-.@-8#$A3('2-@%1
@r9672
ATNGNANAANGTNNGGCTNTAACACGCTCACCATGAAGCGTTTCACTAATGGGCGTGGCTTCTGGTGCCTGGGCGGTAAAGCGACAAAAAACTACCGTGAAAAGTCGGTGGATNTGGCGGGTTATGATGAACTTGCTGCTTTTGATGATGATATTGAACAGGAAGGCTCTCCGACGTTCCTNGGTG
+
"*(!%&#)')*#"#""##+#&%'#%%*!+%#$%*"))!%%$*(&*#)#$+!!&%'!*$%"("%#)"#('$'*+(%"(++&)%#('&&+!!%%)!#*$"$%)&')&%&((+#&#!!+)#$++$$)$%"!&*)+*$*'%(((#(+)!##($$!"+)'(!*)*)'#!%)%+&#"$(')(%*!)(""%'%
@r9673
CCTTTTCACTNATCCCAGTAACGCGCCCGCGCTTCATCGT
+
D6D!-G3!83E!+2#AE#4-"F1@(HH&%/$%!##GBH$9
@r9674
AGTCTGGTTCAGAAGATAAATCGCTCTAAAGCTTCAGTTGAAGATATTAAGAA
+
G=H6+%E:"7E+2=%7:H.=8D'.2+96D5/(9?>?G3;>G'!&GC%="4B).
@r9675
NCCGGAACTCCGGGTGCTATCAGTTTTTATGTTGAATGCCCGGCGAACTGGAGGCAGGAAGACAAACACAGAGCTCTTCATCATTTCAAGCTATTAAATATTGCTAACAGGTATCGTTTGGAG
+
+'*"$)$*)$#*($#*$%)+')+))&&#+#'"#(&*+!&(%("*&$"**$!*""*("'"+#(#!+#'))"$+"+'"($&%$#**('!#($"*$%#*++"(%#"&)!"$'$"**#%##("&)*(
@r9676
AGGGATCGCAGGAGGAGTCCGGTATGGCTGAACCGGTAGGC
+
7GA8>):A8@6,A=E5'''2,@DD=71,1=%<(%B(%44"9
@r9677
GGCAGGAAGNAGTAGACGAAATCGAATCAAACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATNAAGGCAGAGTACCAACAGAAACTCAAANACCTGCGAAATAGCAGAAGT
+
C/#*!E-8)/G(<52<B<)'/+'+6BG4<?%47=.62G"+?6?H),,.?4@.F&#$6GHC-5+$@11/<=F4#.=&%A9G;CE+>;&/,@#>40B!<H'&7'<&/E-9$/)H=D7$%A3:&4
@r9678
NCATGCTTACGGGCAAATCCCCCCGGTTAANTTTGATTCTGGCCTGCGGATTTTTGACCGTGGCCCTTNTCAGCCTNGCCCTTT
+
$*!&$!*%#+*&!)&%&()#+&$(+#""*'!*%"*&")+"$%$+%&#%+!)'&!(+(#+!(()')''+*")%#"!!*$'&$&('
@r9679
TAGATGTTCCGGTATTTGCAAATCGAATGGTTGTTGCTTCCACCATGCGAGGATATCTTCCTTCTCAAAGTCTGACAGTTCAGCAAGATATCTG
+
'.F-"#G');'?A-@@A/>C'37(+8D%:0G4B,"1#.B9GE#E-%6996-<;('=59,C.8E'B"F,6%0?-9H$'!CH:@75:.#B'*,5.?
@r9680
GCANTNCTTTCNGACGTNTTNNCCGNACCGGCACTGGTGGCCGCCGCGTTTTTTGAGGACTCTGCGGCTGCGGCACTTTTTTCCGCTTCAGTGGCCTTTGCTGATGCCGCTTCTGCGCCGGAGGACGCTTCCTGAGCTGACGATGCAGCCTGTCCGGCGGACGTGCTGGCGGCGC
+
(($#$%!$)%%&#$(%)#**&!'"%!"*%+&%!)&**(%((!(+%)%&&)!##+"$")'(+'"(*&'$+'$!*''**%+(#+)'%&%$%"#%!&&$'&'%#+)"+"+))$*%(($*%+*%(&#&&!(%+)!"%!(&")"$"*+'%"+$')!+(*#'((&)&*$)#$)'$$$+)"'
@r9681
ATAAAAAAGGTTGNCAAGGATATTATTTTTAACCCGTCACCTCAATTTT
+
B1/(7,(?0F=/.B'&,31.D+5CE=B<+@60?6@;3!4-%B'H=C@F?
@r9682
CCGGAAGCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCNGCTTCCCTCCCGAAGTCGAAACCNAGCTGCCCTCCAAATATTTCGCATGACTCAGAACANGAGCCGGTATCGA
+
%E+%C!#1,7"<,4.FFE;.H760;0@>B>$C";)6C+($D?"+0;D=(:(8-<,*6#H*+?<4*08$'68)0(4B'>#"=35)'*&7$A4+2;AGBE%1);5F<E97+%/5)6/<9@8D2D(*@52
@r9683
CCGGCGTGGAGGTGGACAAGGTCGCTGAAGCCTTCGTGAAGCTGACCACAG
+
9@63'+3$-!9H2+5?2:-('>-49&7"%.51/H1&&'%.+(C1>/<21>A
@r9684
GTACGNCAGACGCGAAGAAATCAGCCGGCGATGCCAGTGCATCAGCTGCTCAGGTCGCCGGCCCTTGTGACTGATGCAACTCACTCAGCACGCNCCGCCAGCACGTCCGCCGGACAGGCTGCA
+
(D)525?+77E@5*"$1*3AF=7B%')G(!GF6G<6!"A2)FC?7;?,-CH>B853!:999H2?#-F+$$6AG*#G,=9-$@+#!F=D6*=&&,D?6<-6F@2,6=<+:/A,63;CC7@:@D$
@r9685
CTTTTTCCGTCACCCAGCCACCGTTACGTTGTATCTGAACCA
+
HGF!3H)&*F-/;++FCBG'@A&<"%.#4(3=8=02BB7FE"
@r9686
NCCGGAAAATTTTCATAAATAGCGAAAACCCGCNAGGTCGCCGCCCAGCNACGGAGGGCGAGAACGCCAGCGCGGCGCAGCCGGACGTGAACGCGCANATCACCGCAGCGGTTGCGGCAGAAAACAGCCGCATTATGGGGATCCTCAACTGTGAGGAGGCT
+
'3%-G!4"0>B+:@6.F,,$0-1"F9>8?B&=%-:%7DH>2()5E'<?F).=!+.)9>/?4F+=7<FHA5H!&+>"6F2:80E?#5A;!!7(H;@D6$GEEBG7<-%>(A0E=,>B'>!>:=;.89/4HC2002GC!$%B&3)05@=5,8)(34'$AB/F,
@r9687
GTTCATCAGCCAGTCCGGCATCAATGGCCTCCTGACCGCTGTACACTGCAGCCTCGGTATCCAGCACAACCTGCACGGACAGGCC
+
.0%3?*.43G73:HH"-'H'G/D.8"5#6(#*F82E,@;5*@,B'((+5A,#A(.4&%'%.8+E,6=(21+&A+C-5A<:C&G@<
@r9688
GGGTAAAACCGTCTATGACGTGGCTTCCGGGGCCGCGTTATTTATTTCTGAACTCGGTCCGTTACCGGAAAATT
+
G/H8B?%&!:/'FH>:%/0B7FC8B?0'F4;;:;5%/<509+D=-?AB6%!>,H4+5+C1#2=4G%.8)%90*H
@r9689
TATTGATAAAAATCAATGGTGTGGACAATTCAAGCGATGCAAT
+
BB0093>=*2>:'3C3<!6@>!!"%G%E8=6DH#5BC!>?5A.
@r9690
CAAGGGTGCCCGTGATGAAATTCAGACACAGATGCGTGATGG
+
HC1F(-;D9,C./C#D,0B4$"#H.&1A2D*9,*5!D"F(6G
@r9691
CTTCACGCAGTGCCTGAGAGNTAATTTCGCTCACTTCGAACCTCTCTGTTTACTGATAAGTTCCAGAT
+
>+<-/&<)1:A,*?)?='2?5!$6!D0A>A=31H2%8&-D-/<DD)>#/0+@,07;D,E7HA<@&-(:
@r9692
GCCCAGGTCTTTCACCGCTGTCTCCAGCTCGGAATTAGAGCCACGACGGGTATCCAGCTTCTCCTTGACGGCTTTGAAGGAACGGAACAGCGCCCAGCCTATCG
+
DGA9#<5#:.5%!#<-;'*)<A&:):((7DCD@H99,?/>!58@*$F<6AH74A>)'G.;;417HEE/#6"*#9F'FE/:*,A=+>FA"7-$-<3F?>'<!:/"
@r9693
ACNANTCAACGTCTGAAAGCGGATTCGCGTAAGGGTCACCNCTCCCCTTATANACCCACGCAGGGTGGTCCCGGCACCTTTCACCGGCATTGTAGGATTTGGTACAGGCATAGCGTCCTCACATTTCATAGGTAATGACATAA
+
"$!%%+)"(''%"*)$')&*"!$#(!"*!+"&*##"&$())'$&#'**$*''$+"%$*++*#)&*)#""+'"$*#'%$)("*#'(%!%)#(!&%)%#)!#*!%!')!$")+#)'''($'%!$*'($#*(*"('#"+)*"''*$
@r9694
TAAACCACGCCAGCAGCGCCTGCTGCACCTGCCCTCCGGGCAN
+
2*:>(+@+0,:(E7'2#@!*6@4)D*A>@2!12$6DB/6&F(/
@r9695
AGATATTNCTGGATATTGTCATAAAACAATTTAGTGAATTTA
+
:;2327:';97&!E4719A./8)3:FF7A-$.,86?C'1+?'
@r9696
AGCCAGGAACTATTGAGTACGAACNCCATCGACTTACGCGTGCGCAGGCCG
+
HC(+(FC2?9;>5D0FH$G<">@B;>4%D;-E+B5;/D?D25';,4?<0)&
@r9697
CATTTACGAATGTTTGCTGGGTTTCTGTTTTAACAACATTT
+
(1G"8;,E9%02697@5E;$!E(:!<B=>6.*.6,"4.C+8
@r9698
GGCAGCACAAATGCCACAGGTTCATCCCGCGTGGCGTGAAGTGCATCAGTATGCAGCTTCACCAGTGCCACGACCGTGACCAGTTCAGACGTATCCAGAATCAAGGTATCCGGCTGCGCTG
+
4D!FDA*<C%!1@F9&+#%.$@(@4<%0G>)'C;(7B6.#'$@C1FD0A"2!7@6?$C,1)4:(9.'###D0/2@B!92D;6-GE?;;+0D$/95H*A"=62D!B*AG!)A'C&:C$3+%E
@r9699
GCGCGCCCGCCGGGTAACTCACGGGGTATCCATGTCCATTTCTGCGGCATCCAGCCAGGATACCCGTCCTCGCTGACGTAATATCCCAGCGCCGCACCGCTGTCATTAATCTGCACACC
+
-$"%>/?+<1.%#82=29:&.0-7($7?->=G$+6,0'>"&>'6%0E67;9+@;.!?/$1+G>#D1<&%6:C@96E3E=1(8&%2-60-+@G,;@)8D-)!@C@B0*#2-B$?>AD!29
@r9700
GGTGGTTTCCACCAGTGCCTGTACACCGAAGGTAAAGCGCAGACGGTCGATGTTTACAGACGTAA
+
;9.?//?%7+$>)H,72%=90A8(<F#/58HD?:8G/+)G!$H2BD37*!-HG2)893*F#!05:
@r9701
CAGCACCGTCGAGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTATGAGTTCTGGTTCTCGGAATAGCAGANTGCGGATATCAGACAGGTTGAAACCAGCACGCGTTA
+
3'=8G(B37!</"F<+&351'-$97G!H;8=7F@12"0FG9;*0AG.4#*+B$#0/."%@823=#+'2*@:6B@6!5@0927!%&8H3?+FB?@(8=&81:5,3G%?</F<:(.1,+<"#-E;0.%1!@0<3+:*2G.HB6%;6>(.;,/C
@r9702
TGANGCAGGTATCGTATTAATTGATCTGCATCAACNTAACGTAAAAANAACTTCAGACANTACAA
+
#*)%+%++!+&#&#+))"*)'&*$"$"((&!$)%!$!($$&%(%$*'#"#))#*()!''!%&*#%
@r9703
GGGTGGCACACAAAGCTTTGCACTGGATTGCGAGGCTTTGTGCTTCTCTGGAGTGCNACAGGTTAGATGACAAAAAATTAGCGCAAGAAGACAAAAATCACCTTGCGCTAATGCTCTGTTACAGGTCACTAATACCATCTAAGTAGTTGATTCATAGTGACTGCATATGTTGTGTTTTACAGTATTATGTAGTCCGTTTTTTATGCAAAATCTA
+
$*A6<<A0?<=81&9$GC9C?*<9=*5)9>$"C03>!!9C(8#"(/0!555:"4%1FC5F==?B1?>--26;!038&?+9?>D=$$6"F@<H/3*4BH5G"H%4)7"&<$/@3,,"&$E8B-50,E4(<3,)75"07D;F(D-H-5+867)B$)#38AG(0)G>D*-&B)6:)/=6B9E?,+!8/(!-$4>)--3*0)(/@?>4%-.#/D95G4
@r9704
ATNCCGCGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCNCAATACGTTGCAGGTTGCTTTCAAT
+
+#'+(+$++$)*()%'"$('#!"!++#*(()!%#"%'##%!&"(*)#**$!$#)*!$#&(')*&!%)#%*"*"#
@r9705
GTTAATCATTACCGTGATAACGCCATTACCTACAAGGCCC
+
2G/C'7"4BE";C>5@H=68,?;6/!4.@8=:58+3&H13
@r9706
ACTTCCCGCAGCCTCTGTCGCCTTCGTGGATGCCGTTGACGCACTCCCCGCCGCCG
+
B##G@?>;50%>896.38.+8><AH.13><?7H'868FC@;63.D1,)B9G8*&?'
@r9707
GGAACGAGTTNTAATCTGTCAGTGCAGAACGCGCCGCCGACGTATGGAGTGCCATATTTCTTTACCATATCGATAAATGGCTTCAGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGTTCCGGGTTGNTATCAACCTGCAATACG
+
**1A:*@/C/1;5;6*DE?F%1G&70>(@6)H96FD=+&9/G,-G!=57/3<";#-DG)E,(@4F&">.H46A+3E393(DG!AF.-?95/45=1D/*GD!F=%B$#!H:5G0D:6)@;,H$*-6".F2F8:9*)<=H4%.>A@<*E>7-D914!C@=F@B>/@$AG-0,!:C)DA3
@r9708
TGCGCCATTTAAGCTGACTTTATGGCCTCGAAACCACCGAGCCGGAACTTCAT
+
D$:(@D9:%"2?1B"=4EE5F'B)'H7><9FD*H;2/?&4;+BH1!86*50B&
@r9709
NGCCGGACTTCAGGCCTGCCANCCAGTTCCCGCGAAGCTGGTCTTCAGCCGCCCAGGTCTTTTTCTGCTCTGACATGACGTTATNCANCGCNAGCGGATTATCGCCATACTGTTCCTTCNGGCGCTGTTCCGTGGCTT
+
+%8<:1+G<10*76.<'8!E<C>/@'C*D"'-7./F026FB79((>4EB6=D0.G7;)'/&9$H1.H7?HH30176B+1CF7?C/80+?-:-4D:<054#H?=6B-71088<=%0#B'&:F>'C.:+3;3!>C<:799
@r9710
ATTTNTTCAATCATTTGGTTAGGAAAGCGGATGTTGCGGGTTGTTGTTCTGCGGGTTCTGTTCTTCGTTGACATGAGGTTGNCCCGTATTCAGTGTCGCTGATTTGTATTGTCTGAAGTTGTTTTTACGTTAAGTTGATGCAGATCAATTAATACGATACCTGCGTCATAATTGATTATTTGAC
+
64)+/A4=F!:'+F>#/1$"-C171$E6DF*-3)408D%'(1&A@-(),B6G(:.,663&@<B-*-6-:!-'5EG,%A!12AG.$$HH@-DA0#A0&-133H$&AA7%#84@61?24A#8%,4;(E-C=/,0+G58!)83:(BD6/>*A?:=&4$/?,F6@GGC90=481D$+;4/,6*;'+<7
@r9711
TCTGCAGTGACTTCNGCGGTCAGGTGCTGCACCGCTGGCGGCGTGACACCATNCACCGTGCCACTCTGTTCGCCGTCAAAGTGCTGCCCGTTATCCACGATGGCCTCTTTTTCCGGCACATGNTGCNCGGCGGTGATGGCATACNTGCCGTCGTCGT
+
09=$+@/*/,96)<3B!,)*@5?D3,@7C)$>.&:(@%*<#,"D04(GB&.6@#/+:8F)<+592!D+8'4@"'<2H&6%B*>5D6?5B'"693H"064H!)$'+"47C@02.7A8%GAD37*%'8137,:@5$%H/-0,;F4.E%%A;/%1,2"&6
@r9712
GNTCNCGNANTNTGGANNTANATTANGNCCATCTACATTACTGAGC
+
#"&#%)))!)*$'&)*($(*$(""$&("(+))#+""'!&#+%)&*%
@r9713
CAGCGCCCGTTCCTGACCGTGTGGCTTACCTGCCGGTATCGACTCCCAGCTGGACCGCTACGAAATGCGCGTATGGGGATGGGGGCCGGG
+
.50@@-C/-E$2*%0#0,8>GG&D-@1E0-FAG+F-5"C@(A,B:A)&&&-@%>!E075(,@?H-!:->!(02#!HG3(,<D#((&C,50
@r9714
TAAAAGGATCAAATGCACTAAACGAAACTGAAACAAGCGATCGAAAATATCCCTTTGGGATTCTTGACTCGATAAGTCTATTATTTTCAGAGAAAAAATATTCATTGTTTTCTGGGTTGGTGNTTGCACCAATCATTCCATTCAAAATTGTTGTTTTACCACACCCATTCCGCCCGATAAAAGCATGAATGTTCGTGCTGGGCATAGAATTAACCGTCACCTCAAAAGGTATAGTTAAATCACTGAAT
+
>'$B"-0DCE+:#F)'B'F9$GD012!.EF+@F@1*10:*'CA;B/12=*5-%?1&%E8;1(65!<;-=H*FC16A>H88A$D;9B*@1E$(4AC;@7)-*@H*92(B')#"FH6<99E#E$CBH>AH&7&)D3%918@%.<.!3C6,==GG#B%E:4'<>$,H*AD@"($C<2%D@EFG9(7HEF;/(/1!!+2:EB#<>5E2$2!$6'1,FB"C"E/"32>H#9+:56E9$9:F7F%7E(G*H71+
@r9715
AAACTTTACAGAAGAGCAATCTATGGTTTTGTGCGCAGCCCTTAATGAAGGCAGGAAGTATGTGGTTACATCAAAACAATTCCCATACATTAGTGAGTTGATTGAGCTTGGTGTGTTGAACAAANCTTTTTCCCGATGGAATGGAAAGNATATATTATTCCCTATTGAGGATATTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGNCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCNTAAT
+
;)2>48*8&:;BH;2D#",=+#&=D<3<+:5.55*2F6H@)475@17;*3/14*16>1!,,C/)'<(D/<6".C!A>4*5>5.=$0-!>5<H%E6,"C48"H8G#7!A&C@3EG:28ED.D?EH=.3B6!7-,;-<F4-H0E*@?DBGFC)?#"+@',";%/>C&23-/;?64@#:+>'14+$B@;,"':"'47)=#9+E!!&F6-B&$DEB6//($)@4&->8/46EEDE,8"4AA"58";+#FF59;@!GD82/1@-"##A3%-C:AB?'E;>85
@r9716
CGTATCCTTCACCCAGGCTGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCANGTAAAATTNTCCG
+
>';6"!/>%?-=3#'>E&B<4*+A1FD7+1>:1(!@<=D?9A;#DB%F(B>*6$)::6;;,CB*BG#@%;-$C;
@r9717
TGGTGTTGTGTGTGAGTTCGACTGGAATGATGGAAATGGTCAGGAAGGATGGCNTCCAATGGATGGTAGCAA
+
B(-&5!?$!.BBDH=).3<DD0#9!$B4%55;E)@$4H43+C.0=$8>F3F%)%F"++8@:0?+0G06/,66
@r9718
ATCTTCTGCCATCGACGGACGTCCCACATTGGTGACTTTCACCGTGCGGGTGATC
+
:3<534!9'/@">-%!%$5#F3:6='41B'/<;H)/$$6A<64'!-;90&'&484
@r9719
CGCCACGGTATTTCCCCGATACCTTGTGTGCANATTGCATCAGATAGTT
+
2'@,2B7.DD6!%FC*?'3#<9A9"':8F=CF",9%A;:0;@93)+!/5
@r9720
GTAAATTCACTAAATTGTTTTATGACAATATCCAGNAATATCTGCTTCGAATGAGCT
+
&11!&"@2)D*H/C7;@,0?((F@87#.)6@H5/</AHDB<<2E)$)5F8#""E#:H
@r9721
CNCNCCNCAATTTACTGCGGCGACGGCGAGCTGCTGCACCATATTCCTGAACAACTGAGCAAACGAGAGAGGTAC
+
*%("''&+$(#)#(&!!!%*"()$#(+#!(#!&+()&!''&'+)++*%#*!$&%+)+%"$%%*'*(())(!!$)$
@r9722
CCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCA
+
'3-'B"E@"B'?E4F1#%-##@B25?(:?G>;-A;::D*::H%8A885+*F799/7%&4D
@r9723
NTGACTATATCCAATGAGTCAAAAAGCTCCCCTTCAATATCTGTTGCCCCTAAGACCTTTAATATATCGCCAAATACAGGTAGCTTGGCTTCTCCTTTCACCGTTGTTCGGCCGATGAAATGCATATGCATAACATCGTCTTTGGTGGTTCCCCTCATCAGTGGCTCTATC
+
!$*!++"$%&(*"&!(%$(**!&!$*!+*$+!)"#+"$)'%'#+&&"%'%#'%)'!%)*)'+%$+*$&!)$"%)"*$)"')'*'%(*$*")+&$+"($$!%!$(&'%(+&(!+)))'&("#$('+$+!%#$(&&"#$)#'%%"&%)!&$''')$+*'#+((#"*%*$$&!(
@r9724
GGGCTTGCCGGTGCGATCACCCTGCCGATGGTGGGGGCCACCTCGCTGGCGGTGGCGACCGGTGCGCTGGCGTATGCCTGGTATCAGGGCAACTCAACCCTGTCCGATTTCAACAAAACGCTGGTCCTTTCCGGCAATCAGGCGGGACTGA
+
/F9(2%.11"%G3"7(<17D=3+8@A%B>():1*A8*E.DA65)/"BG.(%+)H/FACHH*F:CHC8'(31ABD+;FH?<84.<)H+DD2G93-(8(;7"5&:C?1H3"?%)A=G8<76HF//D-630+F2#5#6(1GC!D!##'<7;22"
@r9725
TCCTCAAANANCGCGGCGNCCACCAGTGCCGGTGCGGCGAAAACGTCA
+
F#)+<$D7/$%%0G3E*03G01?&D3021/A)0H/2$8:)4%%=H2&!
@r9726
CGGTCCCGGACGAACCTCTGTAACACACTCAGACCACGCTGATGCCCAGCGCCTGTTTCTTAATCACCTTAACCTGCACATCGCTGGNAAACNTATACGGCGGAATATCTGCCGAATGCCGTGTAGACGTAAGCGTGAACAGGGTCAGGATCACGTTTCCCCGACCCGCNGGCATGTCAACAGTACGGGAGAACACCTGTACCGCCTCGTTCGCCGCGCC
+
;.+@(!@,*(!F!#($>F=73C&&@5634>*<A("F.,)(2%+/"6F@4E#5<.>-2?'B>B)H*4=G$52=.CF313<73&=.?173A=:>CE*4>:=?;0;13@G'=.8*7&?9*C+8+@A=39*G9;*!BH7H)D#H$<)(F015)F-@2@C4$)8=7!*%"@2A@;&%)!%+E1?"CFF28@)7E%D?,@%EB=1E/5>$2!"0H%>*<H#1.#$(
@r9727
TCGCGACGAGTAGATGCAATTATGGTTTCTCCGCCAAGAATCTCTTTGCATTTATCAAGTGTTT
+
B2'D3)6&HBE1*BD,-CD!:4=+5!6A)9$49!;0*;6BA2.78*-&!C?"841.)$C%27,(
@r9728
CCAAACTCGTATTCGTCAAAGGGATAATCGGCGTGGCAGGTAACA
+
$D;;E:9A9*085B7'))--D01*3/#?'5C5@;74/<*!2(.37
@r9729
TCACTTCAAGTAAAAACACCTCACGAGTTAAAACACCTAAGTTCTCAC
+
$458)8,'@B39@45GE)7'(B8BA"H9',E2BB9))#5-)5EH92G;
@r9730
CAGATTATAGGATATGACNTTTGGTATAACAATAATGTTATTGA
+
HD)%0@5=A6$3':+3$'48E-H)B(D(7?('0D?+)*A0G%C@
@r9731
GCCCGTAATCAAGCTGGGTAATGCGCGGGTTGTCCTTTCNCCCCGCAGGCGT
+
/.@'-G:A417#$*17%!<7*G2";+,**;/'+&:2F)9FA<%G:-,!$%(;
@r9732
GCCGGCTGATTTCTTCGCGTCTGCCGTACTCTGNGCCACCACGGACGCGTTACGCGCCACCTCTTNCACGATCAGTTCAAGACGACGCAGCACCTCCGGCCGGGCATCATCCTCCGTCATGGCACAGAGAAAATCATTCAGCGTCCCCGGTTGTGAATCTTCATANACGGTGATGGTCCCGGCGTGCGATGGTGGAAAACCGTCAACCTGCAGGA
+
@#5.&)-:!3";6'=4-#4H"1E8G$G=!E@("D8,-+#*%A#1H.12;90::-/>8#+.-B><.A*#'$$7E1(@=7!;567)F0"+H?H91$F=F@DE%)FC9?.,3<+E.3A;3B<"4F!8>6(((;0-;@96F):C27-C:"A0E64;!C/3?/77D;%%#06"=/6$).#,%1"F2:1A-0$1.5*&##F!;,#53G+7&/+C=4#)??2
@r9733
AGCCTCTGACAGCGAGAATCAACAGTGATAATTCCGTTACGTTACATTCATGGCTTGATCGCTACGAAAAANTCCTGGCCAGCAGAGGAATCAAGCAGAAGACACTCATAAATTACAGAGCAAAATTAAAGCAATAAGGAGGGGTCTGCCTGATGCTCCACTTGAAGACAT
+
8#-C)@9<(=1!8C8<7!DG-A?D>>+=A>-BA$B2."5)".5<F3-EDF3%&0-B($.,H".FF2G7".-4>:0#=FCB469$'G;/+6E1,:>D@4;3;F.5GCA;H<H'?(+A%372(A&C"0'AA@90(0,C1B:&HB!"%;5?04<<"5">=C(."6C'147E1-+
@r9734
ATGATGACGGACCACGACAGGCCCGCAGTTATCAGGTCATGAACGGCATCGCCGTGCTGCCGGTGTCCGGCACGCTGGTCAGCCGGACGCGGGCGCTNCAGCCGTACTCGGGGATGACNGGTTACAACGGCATTATCGCCCGTNTGCAACAGGCTGCCAGCGATCCGATGGTGGACGGCAT
+
=CBH!#,?'#9.3.H07;>B'51C!85A(>B-D%;0?=:1'34950."A+%-<>,@(1+/24-5B<."8!/H:D7*'@05/D(F.&.E,*#.3H+G@8+-C63=..D9++@G'(BHH7F+F@%58=4324@0,$G@"18C->"173*+!.#C"5)'8=52/F:%:-25%%()&'>+>H@"3
@r9735
NTTANAGGANNCACTGGAGAAGCATGACACCGGGGCGACGTTTTTTGATGGTCGCCCCGCTG
+
!!%)$"**%!"+$%(#'"&&((!$)*!)"&##++$")#((!***((#+*'"#")(*(!*$%$
@r9736
ATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGNCACTTNGACGTATCGTCTGGAACTCCANCCATCGCAGGCAGAGAG
+
76F=;234@@D/A;C1=.1$:=)EDH+='!(.".B?@&CE*,-)H&:@.'/2@4H'2@1=G@%@=><,387.(7'45CD39.!31
@r9737
GAGGAAGAAGATGATGGCTAAACCAGCGCGAAGACGATGTAAAAACGATGAANGCCGGGAATGGTTTCACCCTGCATTCGCTAATCANTGGTGGTGCTCTCCAG
+
<37$3;0A;DC<5@CA9@H$76@=,$09G''4C"G"?&7CF!<-786>/CG*#"F6*H;#=?>162"&B9D'E55H+'%3DFH).-A<DDE>>@H)B+8ED7G5
@r9738
ATAAAATGCGGGGATTCACTGGCTGCACGCTCAATCTGACAGG
+
B>!CG-63G/15(2;*E!C::33("B2-+FAEA>F$9*(H0.3
@r9739
CGGAAGCTGTGAAGTTCTGGGATATACCGCTCACCGTATTGCAGGTTGATCTCANCCCGNAGCTTGGACAGCCAAATGGTTATACGGTATGGGAACCAAANGATATTCAGACGCGAATGCCTGTTCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGGTCTGCACTGTCAGATTAAAACTCGTTCCCTTCACCAAATACNGTGAT
+
"'%+$"%!$*+!$)%$$%(((+&$!&'$'#&"&#&)"(#'+"*$(%'&*($&&)&#!"!*#+!)++""()$#!($&#%'*"&&'+"&!'%%+*#'!(#+(&"+"#+"&*'$!(&')%)!*%)*#&%"+((%#!+%&!%!+))!$$*%+""'!+(+#%++('("$$("#!*"#!'#++!*#%!&#("")(&)($$#&&*%'")$""$#&'!&%'#)*&(!*%&('""*($%
@r9740
NTNNNCTCGTCTATGTATCCATTGAGCATTGCCGCAATTTCTTTTG
+
)*$")')(+%&+$&"'''"!*+!++$$)#"$"%"%(&!!*&%(%($
@r9741
GGATGATATGGGCGCAGATAGCACATGCAGACCTAACCAATATTCGAATTGAAGAACTGAAAGAACACCAAGCCGCCTGATGGC
+
=B@3BH4*%,3E:G6"C-(1.C."#8/=6&*,B6%H>3F@HAH1>">C.>&-H+'@32+#*B92@96(.:F>*",'.##,"#<&
@r9742
CTCTTCACGCAGTACAGCAAATCCTTCCAGACCCAACCAAACCAATCGTAGTAACCATTCAGGAACGCAACCGCAGCTTAGACCAAAACAGGAAGCTATGGGCCTGCTTAGGTGACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTG
+
>/,7*.?41!,):$'A!&?#2&&<+C)!35H6'#78#H$3C(9@%+,$9<4F@73;2H4,%*?A>9(A/)?>$$D422(%=!G#:/6222,'/A.)$H%@64939A1;?&(,?%@:%A6)B6!#5*CHDA:&+<'&9'")16E&988-
@r9743
GATTTTTTATCTGTGAGGATATGAACAGATGTCAAACATCAAAAAATACATCATTGATTACGACTGGAAAGCATCAATAGAAATTGAAATCGACCATGACGTAATGACAGAGGAAAAACTTCACCAGATTAATAATTTCTGGTCAGACTCTG
+
/2A'607C>6C@"06"%=58><46-9867+-F5##F(;D*<'<5!.!)/=$))>(;0+@+0;'7B%;0G:?,2HB#+!#=?"*/%C5#D$,2!8<":CD"G<<<6?D#>/(G9:-E3,&?(0A609%@"*/9E'5D@:1,/C,ACG08F:H!
@r9744
ATTAAGCGATGGTTTTAAACATAACCTTNTTAAAGCTATTCAGGATTTAGTAGTATGGCCAAATCGATTAGCCGACATTGAAAATGAAAGCGTCTTTAACACCTCATTACTTAGAGGGGTAACTCTTTCAGAAATTCATGGACAGTTCGCACGTGTGTTAAATGGTTTGCCAGAAT
+
1>.H?--F)(%@E<&@7/!+2F,GD(8!64@996%#6,B-C,"1?4-H""HBC:">"?:4>&+A.:#)55)$;>90D:>C+D:211A8$8%1(H.7G):B))*H(-)26G1$5=7DG!5@39A)./0H7F1;E:7"B3D/H.-H'C;2,274,88F"BGH@B,'G1D-<9,9:07-
@r9745
NNACCTTACCGAAATCGGTACGGATACCGCGAAAGAGCAGATTTATAACCGCTTCACACTACGCCGGAAGGGGATGAACCGCTTCCCGGTGCCGTTN
+
(+'"%!+&&($"+'%"+&))*"&)"$(+&!)!$!%*%$+(**!"*()"%$%#+#)&#!")%((%$%)'+++(!#+**!$*+#))&!**&$)#!"%)'
@r9746
AGNAACNGAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGATCTGNAAGAGGAGCTTGA
+
&!)#"*%+'+'')("%"++&&$"+)&#%(&"&+*&$++)&'+*)&+%(+&"+)"+""(*)!)!'#+!#('+#++*!'$*)+"
@r9747
CAGTTGNTGTATCAACACGGTTCAGCAACACCCGATACTTCTTCCAGGCTTCCAGCAACGAGGTTTCTTCCTTCGTTGCAATTTCCAGATCTGCAGCA
+
B0,<F=&:-*',$G,D($3($>%5FE22"AB*0'+'*A-#%&%9+=HBFB0'4:<'66"!)CC5+(@H$1C07?>('-0:*B-.%;F!-G5@-ED?.7
@r9748
TGGATGAAACGAACAGAAAAGCCCACTGGACAGTCCGGCACT
+
5:390>,$=77#<$.:");B+CA:F5A2<2C14<!/A/%4<B
@r9749
AGAAACGACGACGAGAGGAGCAGAAACAGAAAGATAAACTTAAGATTCGAAAACTCGC
+
967,;8:%&%8///A@FD(G"7)@#H<%<;;+,)'B+<-;E>1;'%B479*#-?F/;!
@r9750
CGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGNGTATGGGAGCTGAAGCTGCCGACGNTGCGNCAGCGACTGTTCC
+
B$"H5+B$:G#!B:#7BF%6"$!'!-("*A),8;H&,936BB,5.;AF7%*BD2!'/F#G+#!D.2)>3"E3FG,='((HA5F5;G;5B<-%
@r9751
NGGNCCCGGAACAGGCATTCGCGTCTGAATATCCTTTGGTTCCCATACCGTATAACCATTTGGCTGTCCAAGCTCCG
+
"$'(!!$$%+()!!%*"+&#%(&(+&")+(!)#!(+%+"+!+()$!**'+#)$'&&%'"#($)%)+*+("+'#''&*
@r9752
TCTGAATACCGACTCAATAAACACGGCTCTGTATTAAATGCTGTATTAATCATGCTGGCGCAACATGCTCTGCTTATA
+
?2@&2"4)<1C:,';$>(4%:8EH0:5,88=+2'808/H"<;D0,21DA@*1(8/)&0D&+B;)7C(=G#-,0<0.;E
@r9753
CTATGAACAATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCAA
+
HA;H=,DC:+&-.@D+7.4/>!C'0:FE?3==6C$3F/.A?2&>2?>HC.!%A0E6C
@r9754
NAGCAATCAATCATCATTTGCTCATGGTTTNCACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTCTCTGCACCACGATCAACCAAA
+
#+)#+*(""'+""'#+&"%'%&"$$#%*"&*#&"(*&(")$)$(!*&"!")("(!&)#$'")''#$($(&+'#"%&#%!"!"&&$'&$$'!+)""+"$)((&&'!
@r9755
NCACCCAGGCGGTGCCGTTCCACTTCTGATATTCCCCTCCCGGCGATAACCAGGTAAAATTTTCCGGTAACGGACCGAGTTCAGAAATAAATAACGCGGCGCCGGAAGCCACGTCATAGACGGTTTTACCCCGATGGTCTTCAACGAGATGCCACGATGCCTCATCACTGTTGAAAACAGCCACAAAG
+
%<13B.E%',+;),597"C/A()'?F)G(84:,8F=0GG#>!$E):1,=)C/$G16@'-E4'@84!%")4.=+<5%/6D=E3,.,!-F5'G:E,C"4&'?1A<,G;&$5,/"-;0$%2.4<(15?%0%49A;D;,#+F=1F$$/)$8@F;>*/&93=&<7-&98H-+DA=-)>6",8B>/?,+',$-F
@r9756
GAACGAGGCCGCAACGAAAGGGTTTGATGACCAGACCCGCCGCCTGAAAGANAACATGGGCACGCTGGAGACCTGGGCAGACCGGACTGCGCGGGCATTCAAATCCATGTGGGATGCGGTGCTGGATATTGGTCGTCCTGATACCGCGCAGGAGAT
+
.2A!&4B>@!0A/?9-FB8,;,7AB"!E.0(+)96;"7/&47("=<,:$1-.@C<D,!?32$8H(<?>/%)$#G=?$")9A(/1%<*6AG<#@96)*63C$A%;7!E3E<?41/!3(11<!5=264F0"=$G7E((5F$!%4#$"62/5=;;GC8@
@r9757
TTTACTGGACTGAATTAGTTGCCAGCTATGATCCATATAATATTGAGATAAAGCCAAGGCCAATATCTAAGTAACTAGATAAGAGGAATCGATTTTCCCTTAATTTTCTGGCGTCCACTGCATGTTATGCCGTGTTCGCCAGGCTTGCTGTACCATGTGCGCTGATTCTTGCGCTCAATACGTTGCAGGTTGCTTTCAATCTGTTTGTGGTATTCAGCCAGCACTGTAAGGTCTATCGGACTTAG
+
H9:5@=.D'HD)2A('C=1,E,9.770B"E4))$C=DH&E3'7#'#/;%5'@"=3<D19H#CAD.@;"(875.'F<4@?1$8B?9,(%&7C.-=5(-FB3>E64:"$<$)8/6=D9@)B+?<6"2E29;&D<F#*D5+)210H&$,<6D<#."C</75:0D.;1C3-52H1HH2,=-9'E69"EC14*C*@48F2$%0!2E2E"&F36?B)*EG:46"6'#D=*%4.(E7!6@&E#7+%@89:$-
@r9758
AACTGAATGGCAAAGGCACCAGTACGCGCCCCACGCTGACGGTTTCTAACCTGTACGGTATG
+
(F'3:>9$316GDD$3#($A$G("#06)+)501B;:,7-5(B))-&,H4:07,A(4)?5"D9
@r9759
NTTNCNAACGTTGTTNACAAGGCNGATCTAAAAGTAATAATAATGGCCCGGTTTGATATTGATACTGGCNGCAATCCAGTACAG
+
!%%"'$%*&(#"*%$&$&*&")*###*!&%+)%'#($%$*#$"+'"(#+$)"*)*+'(()%&'!#)&&*"&*$+!$(#"&(#**
@r9760
GCATTCACACTGCCACTGATATCCGCATTTTTAGCGGTCAG
+
60#GBG*=HHE0,G(<@C(&6=26;<07D""$1?!!&+4H"
@r9761
NGGTCATACCGGGGGTTTCTGCCAGCACGCGTGCCTGTTCTTCGCGTCCGTGAGCCTCCTCACAGTTGAGGATCCCCATAATGCGGCNGTTTTCTGCCGCAACCGCTGCG
+
%791E!<D<5D66&43DB5/'*?#G3*)!HAC6"%'7(EG2/**=1@>%"-!(,&>+3&88."F*B#25$DF/$A0F&EA#<1$=>#G7)FB@43!66F$FFH#2!F"-=
@r9762
GACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTC
+
=:F@;A/?,?%"*!'C78C%H#HHB8E70E/':$865%&F-F:C/73"'>$'GG,#'0*(@HB5<3;.
@r9763
NCNNANNCNTGNACTCNNGGCNNNNCATNGNCGNNNAGTGACNCGTGNAGNANCNANNGNGNTNNAGTGNNNAGNANGAAANNNNNTNGTGNANATTNNNANGTNNNNTNTGGANATTGNNTNGNNAGANGNTNGNCGGNCCAAGTCNNGTNNGGNAANATNNNTNN
+
!#$"#"!""!"""!#!$"$!!$!"""#$#$##"!#""$#!$!"$"#"!$#"$!$!$"!$"$"#!!"#"!!"""$"$$$#"#!!##"$#"!""!$#$!#$"###!"#""$#"!$$"$$#$#"$"#$"$$!"$!!!!$""$$!$$!##""!"!$!!##$#$"#"!$$$!
@r9764
GCCGTTAACGATTTGCTGAACACACCAGTGNAAGGGATGTTTA
+
F(AB(.2/6!2..7!88>C50)8<#3(8-5;*8F;!(7947?3
@r9765
CAANAATCAGCCGCCACGTCTGCCTCCACCGNGGCCACGAAAGCGTCAGAGGCCGNCACTTCAGCACGAGNTGCGCTGGCCTCAAAAGAGGCAGCAAAATCATCAAAAACGAACGC
+
6?!4&!7*"4.-H+&048('2;&('H$=%#0;*.'?B&,,;58FC)-(?/8!C!/*+!)*#'%.)'<B>D,,#6*1G@'G+)5:&6@#."AG(HA4/D*F!&:9;'G&H5='0H1H
@r9766
ATTGCCGGAAAGNACCAGCGTTTTGTTGAAATCGGACAGGGTTGAGTTACCCTGATACNAGGCA
+
0(<-@!2-;H34'-8.=>7%?FC(,0ECEH-($4/$.F6%)+13ADG*$,2,3F$:'5ECF7+"
@r9767
CGGGATGAACCTGTGGCATTTGTGCTGCCGGGAACGGCGTTTCGTGTCTCTGCCGGTGTGGCAGCNG
+
F;58GB(;&'<'.*9H695C8/21)3&G2EGB&;-$8)2>34C;@(!1%=-;+8A($56??@H=C.,
@r9768
AAGTTACCTGTCAAACGGTGCAATGGAGCCAAGTTAGAACTCGTCAGAATGAATATTATCAAGCAGCAAG
+
?%)'4&;51)'.+%F2'05/<BEHB=:7!B'&4>(7-E3.;-2(@?9%3E*(>"$.>'%G-++B3D(D;/
@r9769
TGTACTGGATAGCCGCCAGTATCAATATCAAACCGGGCCATTATTATTACTTTTATATCCGCA
+
;6=2401(@A;'549"/@-5C%?71?.+1/H/*FD+'B=C<7/.E5+9;)36-F&;D93B%5.
@r9770
TTAAACAAAATATTGAGCGGATACGGCGTGAACGTCTTCCGAAAGAGCTGGGCTATGCGCTGCA
+
)BE$:H=<<,9"C9ED<!8%1F7%/(H<A$0A,&);3.$G%%,E&A;*)1>D-96;@'7)&HF#
@r9771
TCCACTGCTTAATGACATTCCTTTCCCGATTAAAAAATCTGCCCGATCGGATGTGGTCGGCCCGAAAACAGTTCTGGCAAAACCAAT
+
@$GH"D-;D4.0!<7>3?+*;/;"D2+&&087"'#%)#F$$)6::$?C*;%1+E%B:/?0F=<-"B1@7"376-<+>329@8-+:-&
@r9772
NTGGCTGAGGAGATAAATAATAAACGAGGGGCTGTATGCACAAAGCATCTTCTA
+
#%+'$+!'#)'##$')+"$*&(%!$!"+&(%($'$%$))$!!%&)("))!*'&&
@r9773
ATATCTGCTTCGAATGAGCTCTGGACATGCAATTGTTTTATTTACTATCACAAGATTAGTAGATGTCGTTGGCGAAAAGTCATTAGTTTTATTCGATGAACCAGA
+
<!%-?%?!#(+>9-=!+D)"$2+5@3?%79+:&"D'F;"?H#8G.!(8B(DD3.,=:*#F(2A9"<"=;!0-134H8C=H*C#$+1(#9=*:E/H0DH*98<:G?
@r9774
CAGTGTCGCATTCTTCGGTTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAA
+
C7DHF(4<0%23<<00,C9.=12"&6E#D,-$=+2=D!3BD9)D14!4)."A.A@*
@r9775
AAGATGAAAACGCATAAAATGCGGGGATTCACTGGCTGCACGCTCANTCTGACAGGTGCCT
+
<.E"GEF.GH1/&>#;B5>B$4&=0F;*!@A3"<H.89DE)"1A%<@"?>F::75-1#'4G
@r9776
GCTTAATGNCATTCCTTTCCCGATTAAAAAATCTGTCAGATCGGATGTGGTCG
+
G#*E;1'>"7=(+>>A?27$C"0**@0H/4*F26?3F"+@69>3/#7#.B=)4
@r9777
GCCATCACCCCCACACTGTCCGTCAGCTCATAACGGTACTTCACGTTAATCCCTTTCAGATGACTCACACCGGTATCCCCGCCCGACAACGACGGCAATGTACCCGGTTTCACTTG
+
6F*++F8;>)96*6<7*,!;$=&;).")39,4;6%4&@3GC&G%+.<>68*EF&21A)+'C7,.>&/!96$,8E;0@$3A:B4*D'::*52C">F+BB?7,E8.8H8/,)"!D(B(
@r9778
CCNTCGCGTTNTTTACTTCGTCGTTCGAGTGCTATCTTGGTTCCACACTCTGGAGAGCACCACCACTGATTAGCGAATGCAGGGTGAAACCATTCCCGGCATTCATCGTTTTTACATCGTCTTCGCGCTGGTTTCGCCATCATCTTCTTCCTCGTGCATCGAGCTATTCGGATCGNCCATCAGTTCTGCGCAGCAGTGCTCACANACGTGAACTTCCAGCACATGCAGCTTCTGACCGCAGTTAGCGCACGTTAA
+
!!!+"""&'!(+!)%!)&*%#"('&'+++**&)%'*&%*#!+&)&'"$&#'+!+(*$+('#!)&(++'&#$("#*##$#"*%#%&+!)%#*"'+)%(("$%!+'+#'!(()#"%+%))*%!!%&&%*"$(%&)#$*!&+%#+*"'+(%)"#!"'$'%$+'"%%&(&))!((!%#%%)$#)$&))+%&!$#""!"!()'("'++"*(%"'#%%%%%$#)%")(+(&'$)'$%"!*"%+*$(++&&'*')"%"'*+(
@r9779
CGACTTGTTCTGATTATTGGAAATCTTCTTTGCCCTCCAGTGTGAGGGCGATT
+
+2G<#/;<+,/:(D"(8.@/$$:=;&AA'2:7A0A$"'8E4C/8,:'/1/2@&
@r9780
ACTAAGTTGGCATTATAAAAAAGCATTGCTTATCAATTTGTTGCAACGAACAGGTCACTATCAGTCAAAATAAAATCATTATTTGATTTCAATTTTGTCCCACTCCCTGCCTCTGTCATCACGATACTGTGATGCCATGGTGTCCGACTTATGCCNGAGAAGATGTTGAGC
+
-*?,0+*EC62/E;8"4(1E+1.12EE#EBAEA.>.5%0$&*><31?B!E6)!FF54/6.0(:E&F@B(D6)D3)$<FF<+2#/2DH+B&,9E8)83"3=2FC39H70;%/8?80.%>$?94+2E+,H2.D942AG3'&)D<<58*?D<"8F3&GC0>*F"(90&?$@#16
@r9781
NNGNGGCGNCGGGGAGTGCGNCAACGGCATCCACGAAGGCGACAGAGGCTGCGGGAAGTGCGGTA
+
)#&!#'()*+$)'+%+%$)&)#%#%&%!$%!*!%&'"#))(!((%#!(##(#))&""!&((()+)
@r9782
GGGNATNANGGAAGTGGAACGGCACAGCCTGGGTGAAGGATACGGAAGCAGAAAAACTGTTCCGGATCCGGGAGGCGGAANAAACAAAAAAAAGCCTGATGCAGGTAGCCAGTGAGNATATTGCGCCGCTTCAGGATGCTGCAGATCTGGAAATTGCAACGAAGGAAGAAACCTCGTTGCTGGAAGCCTGGAAGAAGTATCGGGTGTTGCTCAACCGTGTTGATACATCAACTGCACCTGATATTGAGTGGCCTGCTGTCCCTGTTATGGAGTAATCGTTTTGTGATATGCCGCAGNAACGTTGTATGAA
+
"&'"*&"%&'+%'#)("')$%*"(%"(($$"#!'!%!+)+(+#$!"#(+%*%"%"+'+(%)''"('$)("'$#'"*+"##'#)%$)%()#'$$)*+($&'(('"$%&!#)*%"('$'%&%$(&)'((("+!)(##)+")$%$!+#%()!&"$'+#"!$*()*&%+**)##!(##"&*%%%#'$'%$+"#*"$!%%$)&&&+()'+!)+%*(+((("%))&$)(+")*$!&%#%($#$"&*+!%+&&!$&#'!"*#"($((*'+#'%#*)&#%+&'!##!!&(%)#*!"#)!"(!""'%#+#"))&'&!'+
@r9783
CGGCGAAAAATAAATTACCGTTTTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATT
+
1?6#4<:76>"H6F?/<*C!-3":#E('C-6(1A/A%..@E-F4D#+3.A%)6@&;F!FD>$?,BH(?5%=7322-6B4H61<++%@>3@9?7
@r9784
GCGGTTATCTTCTTTGCATTCACCGCACCGATAACATCGCATCATGCAGCTTCCCTCCCGAAGTCGAAATCAAGCTGCCCTCCAAATATTTNGCATGACTCAGAACAAGAGCCGGTATCGAATCTTTTAGCTCGTACCATGTCCTGATACAGGGCTTGA
+
C'1(:@7-$+;%(:0FF$<>#D:0H:777?9*@"+@+"$'F!&>HFA<#,:(9A368:'4?E,"?5#(B6%3G.C>48?%,D(&(;53.>#=E/,2630<*8@=!D>.,+@(9*+C:A10:(!1@::+06D"<H!<BC8*F$/+,.,=:,D;C'$1E/@
@r9785
TGGTTGACGGAAGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAANGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTCTTCCGCTGCGTGNGTATCCGTGAGAACGACGACGNCACGTATGCCATCACCGCCGTGCAGCATGTGCCGGAAAAAGAGGCCATCGTGGATAACGGGCCGCACTTTGACGGCGAACAGAGTGGCACGGT
+
..=)2!;#+B'@4B-A9&F>$G/%(',"3*%7/>$==D72!,H5G5))&?$$'6B,=-,;C1,31'5("?#3;AC$>;5.';>4&%>2A4:9E"1&7;(;0H:3:%=#51-'/,/7&E#429B$%+)>',#)7'1>22,@1<.);3:%D/.@>;&!.H0$4B=0=:#DB10.C8=DD80:"C""78G;"7G8&3=1:EC+9?E2G((/?/-A)<(H>*,"'-(%&#3;A=$$8$6E)2=#.24C.3>?<D'727D1<>?/"9*B!9)+9=C
@r9786
TCAGACTTGCAATGGAACTGGCTGTTGTTACCGGGCAACGAGTTGGTGATTTANGCGAAATGAAGTGGTCTGATATCGTAGATGGATGTCGAGCAAAGCAAAACAGGCGTAAAAATTGCCATCCCNACAGCATTGCATATTGATGCTCTCGGAATATCAATGAAGGAAACACTTGATAAATGC
+
A5"#35.AAFHAC?@6.175=8>6E-B'EG=E%7*D($-"*<!9D6B2?')#E=10@BFF9:75=#C,0).101@E=CD3?.=+9,EA*B<9-*;8(53(%B-#7D'2D,<.9.=?/<((;@"08-;'*65>D-/,+$%?E@B"?.-?(-+?.;77(*C,0",DB+.--BA&3F#ADD%8G/)
@r9787
TATTGCATGGTGTGCTCCTTATTTATGCATAACGAAAAACGCCTCGAG
+
)52*-"DD-9GD+)=25<8"(-&+C?6AH6B11:,!2/6E6<'2!"8=
@r9788
GCCCGGCGGCATGGTGGCGGGGGCATTTGACTGCGCTGACATCATCGCCCGTGTGCGTGACATAAAACCGGTATGGGCGCTTGCCAACGACATGAA
+
:6*-@+'B$?/E"/<+);#(!$,3+<HA!3-<.?$.>*#%"#@G:G1HEA67B$?)@G)&A$4<&;H=83,F6E3+/5(?7H'-<'/*D'0'+D):
@r9789
GCCTGAACCACCAGGCTATATCTGCCACTCATTGTTGTGAGTGTGGCGATCCGATAGATGAA
+
G$$2(1"9G:%>*:%+3DE",!'&+*5@H*59E#=,CG./97,5(<G2&)!%&'GG?560AF
@r9790
GCTTTCACCTAAGGAAAAAAACATTTCAGGGAGTTGACTGAATTTTTTATCTATTAATGAATAAGTGCTTACTTCTTCTTTTTGACCTACAAAATCAATTTTAACATTTCCGATATCGCATTTTTCAC
+
G%,?>1$#D4D+5HF;$>!!?6:)(201<1'97#2FD#*3'<A3)G!?0<'-';-GF&!?+E:(D-')4*B!H#,E"8D/F,);)27:&B=>2!EGCF4BA978F=F/87B6;=>")F4.57@<DH&.
@r9791
GGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTGCATTNTGGCCAGGCCGCGCTCTGTCATTTCGGCTGCCACACCGGCAGAGACACGAAACGCCGTTCCCGGCAGCACAAATGCCACAGGTTC
+
G0(3:(5#:G?#023!)F,:BE.?2(6..4?&2(<0<,20AH8;B&23C6CC45:+/4;%7.5&(+/>:50&H@2#7,<6;7>'9D5>&>*7/0DG<3!B>>0E">.=<0;$1))0H)6,2&GE*<@
@r9792
GTTGATGATTTATGTCAAATATTAGGAATGTTTTCACTTAATAGTATTGNTTGCGTAACAAAGTGCGGTCCTGCTGGCATTCTGGAGGGAAATACAACCGACAGATGTATGTAAGGCCAACGTGCTCAAATCTTCATACAGAAAGATTTGAAGTAATATTTTAACCNCTAGAT
+
):.DB8:B=4)*3#'5/9%E7-C12F:>%59GH<E(2.2G9)"/""0$4+G<B)))*'8($.B!=;%F?+"3A)93='2=#9;)G(HG/?3-C@0&7/3'A(.-5.:21578=HH?37F#D?(4*%##@-$HE0071(E%6A%4:(,'0*%:63)-(C;94*71+%-F::/CH
@r9793
GCAAATGAGAAAATCAGCCAGCNGCGCCGGGATTTGTGGAAGGCGGAGAGTCAGTTCGCGGTACTGGAGGAGGCGGCGCAACGTCGCCAGCTGTCTGCACAGGAGAAATCCCTGCTGGCGCATAAAGATGAGA
+
G-':6(EE?'E3#A03=1G;,G1$7=$'36;6.53$=F#*<F?B@=,5*G14'5D(.!#>>8=#9HF$20$<':G21@C1@)+2(;,GEC&%@7%).@*.<H,552(A!>=.(.C"F7?A:7<.F/-+'9B-B
@r9794
CGGGAAAAGGCACGGGCTTCTTCCTCCCCGATGCCCAGATAGCGCCAGCTTGGGCGATGACTGAGCCGGAAAAAAGACCCGACGATATGATCCTGATGCAGCTGGATGGCGTTGGCGGCATAGCCGTTATTGCGTACCAGATCG
+
4H:H@88-:*,94>%BE6F#$:73CGF'F:G.HC-'#%3$33F/;.##16>0)8611D+<!=8F;1@E2*,C3,,.!$94=GC"$DB;>$#D#6A=#59G$4?%;-7-(H7B*;9/?(4AHB$H=">-$DAC$!',"FC7*/HD
@r9795
GGCTGCGCTGATCCCACCTCATTTTCATGTCCGGTCAGCACATTTTCCCGGCTGAGAGGGGTGTCC
+
2*C5D2-B<1;$A1F/E&=51),9%*&.5D(-D=,00"17E3;F9;/,!E($+"=110C#(4%?D5
@r9796
NTTACGACGCTTATCGGAAGTGAACGAATACTTTTTATATGAGGAGGGCTGTTTTTACAAAATCCGGTAGTAACTTGCTAACCAATTCCTAGGCAGGTCATTGGCAACAGTGGCATGCACCGAGAAGNACGTTTGTAATGTCCGCTCCGACACATAGCAGTCCTAGGGACAGTGGCGNACAGTCATAGATGGTCGGTGGGAGGTGNTACAAATTCTCTC
+
$E/50*1&*8<6@(?;'E&*!$<D?51++)AB=#C-F.871!B-8)*@07)3$5003FG;+>./-@5;<D;089!F-"&F'A&:0755&0:23A$B--/?"&65$=9#=.+">9"@.53);G%34,@"!/,2HC*:5-.CH#30)A!?"DA)H?70?#%/-9FG+HC&A<5?;$B8==*"*2.0,'-D*6/AE@$2%.5G?",69%#G6+$8,BF7B6>
@r9797
NTANCCGCGCCNNGNNTCGCNNANGNTNATNGNGGGAACNNCNNNNCANNGTNNNNNGNANGGANNGTNNNNNCTANNTNTCGANNGNATCNNCNNCCAGCGNANGGNNNNNTGANACGTNGNCTNGTCAGGGTNNTATCNTNNNNNCGNNNANNANNGNNNNCNTCTGTGATGNNANNATGGANGGNTCCNNCANCNNTGNTNGANNNAGANTNGNCCNNGNTGNNCNNNNNTNNNNT
+
#!$"!$""#$#!!"$$"$##$"$$!$#!"$!$""!"$#!""""!$$$!"!"#$!!!!$!!#$$""!#""#!""#"$"!#!!$""#$##"##!"!!!!$!#!"#$"$##$$#!"!$!$$!!""!$""#$$$""$!"!"$$$"!!$!$"$#""$$#$$$""#!#$###$$"##$$#"!#"""$$#""!!"#$$""$""$$"!$!#!"#!!"$!$$#"!!!#"##!$#!"!##$$!"$#"#!
@r9798
ATGCCACTGTTGCCAATGACCTGCCTAGGAATTGGTTAGCAAGTTACTACCGGATTTTGTAAAAACAGCCCTCCTCATATAAAAAGTATTCGTTCACTTCCGATAAGC
+
>DBA9&3@>*GF-C*+HG"C>E-@#.-3,!?%+8@$"/$F7#26#3-%(.AC1>6)!0>H6/'9)!0!B'E7;@8+/#(=/"+A&0=70C/A%A#FG$!:=2@D?827
@r9799
CCGGCAGCAGTAGNACCAAAGGAAACCATCATCCTGACATCATTTCTTCGTTTCTGGAATTGGGCAGAAGAAAACTGTCGATGCAGCCAAAATTTGTGGCGGCGC
+
68'%E&3</4;AGG7H1=8G,?,"=D,*2*1%3&<32/4!%H8><:;4=H'-12:#4AE.*8@&.@:!"#0;A*$6G,,@.7-"G"6B*/(D85@4>33A#2/8/
@r9800
NTGATTTTATTTTGACTGATAGTGACCTGTTCGTTNCAACAAATTG
+
!5F,:H(GD$+0!1E$6C!<-?&>73&%39;B2C?7/B;5:C7/!"
@r9801
TTCTCACCGAATGTCTCAATATCCGGACGGATAATATTTATTGCTTCTCTTGAGCGTAGGACTTTCCACATGCAGGATTT
+
/&//5(A-G+>%FG?E;/93H@0=7<@D2,88CAH1#E'#*A,:.D,1?:1:F/3%F?*C43/.$&+F<.("B/C+0?<5
@r9802
ATAAGCNTGTCTGTNTTCCTTAATTCTCNGCTGGCTGATAATCATCACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATC
+
D6?.#$$D.)@AGD@656<F5D7?B21+,;'H?D"))B>=8D=63"*10#"@!67E.E"H*#5F';)>AC(025095"+&$'"383H
@r9803
GAAGATTTGAGCACGTTGGCCTTACATACATCTGTCGGTT
+
'2,D8$29>7>7G"C":<F!-.<,F&AAE54FB:C>.4,D
@r9804
TNAACTGTGCAGGCAGCATACGCATGGCGGCTTTATACTGCCCGACGGAAATCCCCGATTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGANTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGT
+
9E)):3AHC5=<C.,$0CD)#*"B=A>99#E#!?$)9(/F,'1#@D966./)47C;(?$%D!;=8)5GE>$##8"BF*D!57:!3/&=B*DD%(,%3*<>+@HH/!33)D%%7"'),+-.F='4C<40%0@?4:/9>A6#>8,1D0$,(G1%#E+8B?'&.%G-HF;">B:
@r9805
TTTCCATCCGTCACGTAATTTACGGGTGATTCGTTCAAGTAAAGATTCNGAAGGGCAGCCAGCAACAGGCCACCCTGCAATGGCATNTTGCAAGGTGTGCTCCTTATTTATACATAACGAAAAACGCCTCGAGTGAAGCGTTATTGGTATGCNGTAAAACCGCA
+
28&B3(<;BF&*$C/;=*++0(,CD"0<9:+%?)B#+0B17:85)0G1/=-(>17&8@<1H2%7#<!%7*!>D/4>;*D676@8F/.7//,8,E-2D0@#083-=#;A-6H<4/>.0605>9);,88A1?4/A6-5A#AE('DH+5<;@7CF#/C(=E:%3A>5
@r9806
CGGCCCGAAAACAGTTCTGGCAAAACCAATGGTGTCGCCTTCAACAAACAAAAAAGATGGGAATCCCAATGATTCGTCATCTGCGAGGCTGTTCTTAATATCTTCAACTGAAGCTTTAGANCGATTTATCTTCTGAACCAG
+
)CCA&H6H-5.6*E:>%8D<!<,*/;1=/+)!7F@C)D&C#>A4:4D0&BC7823/D82?31.:%@27%*:-.7&<B6%"9;7;=B:-D>2",."(+3.HE+?;7(GH!-2(5-G8EE'<55C>%:C08FH&AG9*F$<6E
@r9807
CGTGGCAAAGCTTGAAGGAAATACNAAGGCAAAGGTACNGCAAGTGCTCGCAACATTCGCTTATGCGGATTATTGCCGTAGTGCCGCGACGCCGGGGGCAAGATGCAGAGATTGCCATGCTACAGGCCGTGCGTTTGATATTGCCAAAACAGAGCTGTGGGGGAGAGTTGTCGAGAAAGA
+
0('0;C@2GG!AH)+!&D&).):&"')&9;?1A'FE9A:>@+@'0)7@$6G9-%A/E63B:B=&+29*-/@45>15$?*B=&>#,4"?7(H!%-F4;>AF43@?.AAF6<@81-A-?C8.5:?@4)&#;,D/0!A<((ADC9D#7#/!38-!'(B28>3)<0=;-F7?.E.#C80<)868
@r9808
GGCAGTTTCGATTACGGCACCACATCGACGAATAACACGGGGGCTCCTGCTCACAGTCTGAGCGGTTCAACAGGGGCCGCGGGTGC
+
<F.+%/86:?D"G%581(@9:+,B32C8H(5B:4B:$!"!7-+G5A$2/E/<,@AAAA0C82=B7!$#-1(.-D,!F:&?>82:@4
@r9809
NNTGNGCTTTCAGTGGATTTCGGATAACAGAAAGGCCGGNAAATACCCAGCCTNGCTTTGTAACGGAGTAGACGNAAGTGATTGCGCCTACCCGGATATTATCGTGAGGGTGCGTCATCGCCATTGCTCCCCAAATACAAAACCAATTTCAGCCAGTGCCTCGTCCATT
+
'"%(!%+*"++!"'(*#+!"'&%%$#(+"+"*%)%%('*+*"%(%%&%)%*+&((&&$&'$)*%'#""$+!*+"#!(*')(&%#)'"'$*"!'!*&!)&#+'#'+&$+)!(#+#*&$+$%$!'*$#*!"*!%$#(%$'&)*%)"++'"+!%%("&($&"&!&$$#+(!"
@r9810
TCATCAAGTGCCGGTCGTGCAGCTTCCTCGGCAACGGCGGCAGAAAATTCTGCCAGGGCGG
+
@C<:G)',?6"!DFD%3<7%!3:?FA!<?#:2C.>>./0(?-2<@;,%<49@66<7:<H2@
@r9811
TCCCAGTAACGCGCCCGCGCTTCATCGTTAACAAAATAATCATCCTTGCGCAGATTCCAGATGTCGTCTGCTTTCTTATACGCAGCCTCTGCCTTAATCAGCATCTCCTGCGNGGTATCAGGACGACNAATATCCAGCACCGCATGCCACATGGATTTGAATGCCCGCGCAGTCCTGTCTGCCCAGG
+
2C'3@;B'D1#,E,+.'+8&:%%:4)3$.)B#:-4#C';D'3*;9;*=2A,@:+7.F7C<*:35!>:-<1#GF'6HF1<H3:F+!G#4/G"A-(5F#9):+?;&D)67/&<4G3>C,)F3+>-%)A1G%7:>B,?5@=-%)<)3G01C%39,*0D.1.G;F3HG"$?B$$/2/>-/20?47A1C(;-
@r9812
ACGGACGTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGTGAAGGTAAAAGTAAGCCGTGTTCCTGACGGTGTTGCTGAATACAGCGTATGGGAGCTGAAGCTGCCGACGCTGCGCCAGCGACTGTTCCGCTGCGTGAGTATCCGTGAGAACGACGACGGCACGTATGCCATCACCGCCGTGCAGCACGTGCCGG
+
+'CC<D906CBB6@GA'">*,&2%+%4*9E;2,F$@=9;A6&:&@EF/@3G!&/GG2/7B$@*)>#A*,@)E'103:+5=G.>A9!'6#<H)90&5H'<C!$4<9..'?6+!)?8.16DA5*3%-#(>##-+"<G./*78!0*9+,3)G27/E#)570H)8@=:BB1B:89?02*?")#0/5>+!'(5A(395>'>'B41#*%;!,0
@r9813
TTGGCCAGTCGGCGCGTTCTGCTTCCGATTAGAAACGTCAAGGCAGCAATCAGGATTGCAATCATGGTTCCTGCATATGATGACAATGTCGCCCCAAGA
+
(ED$H2.76H43329HA(7//4!!3H-A+<+<,25(%*;!19!5<?D,G$#6%,)B133"8$C3$:".6.B03-=11:@..GC31+/3</A,>-4H##.
@r9814
GAAAGGAGCAAGTGTATNACGGGCAAAGAGGCAATTATTCATTACCTGGGGACGCATAATAGCTTCTGTGCGCCGGACGTT
+
5#-#C/+;G9@3A0-A2EC+3*69-2%6'>"4C&3:'%>D00',,:!0+7-/8@8,#@H;32(>">6!F*98)$3<8GE'=
@r9815
ACGAGGCTCTACGAATCGAGAGTGCGTTGCTTAACAAAATNGCAATGCTTGGAACTGAGAAGACA
+
+$&()#$"'#!"')&'$)'"%"'$+*$'&)$$+%)+%&*)*"'&"+!*')&+*%'!'(+)(!")'
@r9816
NCGANGCGAGACTGGCTCTGGAGTGGAAAGCGAGATNGAGAGACAGGGCTGCATGATAAATGTCGTTAGTTTCTCCGGAGGCAGGACGTCAG
+
)5>7&B#D<737D=>">H1&<&3:+CHG0&25='*G&BC93%($EF@(2E;'5..8=3G+-%G2#B?-=9:?A4.B:+-1;7/?+=H2.$E$
@r9817
CGCAAAATACGGTAATTTATTTTTCGCCGTGGAAAGCCCTGCCAGCGCCGTCAGTGTCGCATTCTTCGGNTGTTTACCCGCAAGCGCGTTAGTCATGGTGGTAGCAAAATCTGGATCATTCCCGAGCGCTGCGGCCAGTTCATTCAGCGTATTCAGTGCGTCAGGTGAC
+
+?.9G?&F"'058"@%;%/$4++A@+35)>G*F>0?=!">%;'%?%%5A*-5*"B(=<'2/GE>0,-F$!2>#HC<'8:31:=&395.9:4+;.G8D%5".03/78%-D"19#C-&G$.=:!1:$*&94CB;569AD/>+2#A%AC41F<G!AG/;D:)$0@EGF,3<0
@r9818
GTANCGNNAANGNATGTCGCTGCCACTCGCGCAGCAAAATCAGGGGTAGGGAGATCAAGACTTACGGCTGACGAATACCTGNAANTTTATCAAGCAGCAGAATCATCACCATGTTGGCTCAGACTTGCAATGGAAC
+
"('!$!$"&"%!"*&+(**&&()"('!'&(&()'"#*)!!(&)%$#)!&&!$'&&'!')$!'!&)%!*)&(!#**&+$#$"#+)"!'+#%$"!$%&!%'"%(%!$''$'(%$(%#&!%")%'(%&')%&(##"#(!
@r9819
CAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCTCGGAGAAAGTCTATCTCTCACNAATTCCGGGACTGGTAAACATGGCGCTGTACGTTTCGCCGATTGTTTCCGGTGAGGTTATCCGTTCCCGTGGCGGCTCCACCTCTGAATTTACGCCGG
+
4-/7A8A1/:"BB25?A?/B2+46+:467)FAH'35<D'&70A()'4*%<H,&@1#E*4<:-=6=8(@E<!$.,E43'E..0%;,(4:"05>:$(2F/"<C"0$7:8&8(,=1&=(ED+A(E?BA<8G./CC5A0(%6H-&"'110"/6GC:A.!&G7B4!,?$F)26/2=F@F3-8%/72/
@r9820
AATTGAGTCATAGAACTTCCATTATTCTCCTGAAGATAATAATCGCCNAATAAACCAATACTCNGCTTTACAATATACTACTAACCGCAGAACGTTATTTCATACA
+
*DB<.4*37@'2D&+E"?D2>EB3G721?)+)";:(G:5,A%;?/5.'4$);E&20?HD1@C90)6C7-'%8ED=-081,4)/?/#7704H7%#11B.837F:*E*
@r9821
CTGAATACACGGGCGAAGAGCTGGACAGCGATACCTGGCAGGCGGAGCTGCATATCGAAGTTTTCCTGCCTGCTCAGGTGCCGGATTCAGAGCTGGATG
+
)G&C:H(=5>$*.)14,5(H:%;>.B+%'AE-$E09"/1A(F?.$5028G=(F&*(A!3C=@3C/A/(6B!E.*?93H3=5'("F$!$8;<!D,";,#3
@r9822
GGTGGTCTGCCCTGGCTGAGTGAGGCCGACCGGCGGCTGCAGGTGCAGAGTGATTTGCCGTGGTGGCTGGTCT
+
*-C.<3858EGF"+,D6$G>,F>5B<D)$C@7!.@"F:-#+FE6222;//44#?FE#=0!"CBFE6$&$B5CG
@r9823
GAAGACATCACCACAAAAGAAATTGCGGCAATGCTCAATGGATACATAGACGAGGGCAAGGCGGCGTCAGCCAAGTTAATC
+
9DA)/GA?HG75@B.BC05A%"0F>:50.;>?),>#<",->-$%2=DB"A036D43&F*A''<B..9;/F,A3G6:70!72
@r9824
CACCNCTTATTATCNCAGTCCGTTGATTCAGAGCTTTCTTATGAAACCATTCTAAAAAATTATAATGGTCAGATAGGATTAGAAGGTCGAACCGTTTTAAAAGCGATGATAATGA
+
:E3/,A4%/13@@-B!&H@E5E);F85E00#3$B=B5?4FHB.;<4%,B#0C/7!$,E2-;H0(!%3,"9&H%H;"8$6E.*F(:-7.E.>7$H#*(>7C'E84G&,G&D(8A.<
@r9825
GCAAATTAAGCGATGGTTTTAAACATAACCTTCTTAANGCTATTCAGGATTTAGTAGTATGGCCAAATCGAT
+
6C"@D.&D,+:&98):F8#(A08</$"#H0!</G4$2'>!0!AG0>2=$4(2:"H>F8,,FE-H(G/(;;8#
@r9826
GGTACTTGCCCTCTCTGTACAAAACATNTAGNTGATTAAACCCAATATTACATAACAATCCTCGCACTCGCGGGGATTTATTTTANCTGAACTCGCTACGGCGGGTTTTGTTTTATGGAGATGATAAATGCACTTCCGAGTCACAGGAGAANGGAATGGAGAGCCATTCAACNGAGTTATCGAAGCGGAGAACA
+
+C2<G-G)%5%&?#&6%?H6>#:50EEG6EA%"%-@;)-FH;!/:4$-&.F%"6F61779!$9#>9DE/:69C$%*<.&/*9B=>>1<?9%9/)726H$208!&B.DC*BC#"22,>+7/64<D/1":$!*A#;@D@F.(99:@%D(D3%-G5-+@()#!9B$2=@2+,!*31%/'.D=>'74F.GG@HBF)A%
@r9827
CTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGA
+
-@A29#*=83GF,4>&=G3%C+@-1;3"7:2D&"9F6=)?:"C4?1"'73D:)&/?.&0"G3H'$AH'.70
@r9828
AGAACTGAACAAGGCACTGAAAGACGGGAAAAGCCTGCAGGCGGATTACAACACGCCGATGGCGGCGGCGAAAAAGGATTATGAAGCGACGCTGAAAAAG
+
0&=G%C2!$&H+A3!09"=8FD#>1B)6(6/"H84E7;<7!0%'>07>!((#*?5G:&7;3,0.D%%0%86#094?1+..(EBF+0"4.=;>B>-C6F&+
@r9829
GGAGAGGGAAGTCATNAAAAAACTAACCTTTGAAATTCGTTCTCCAGCACATCAGCAAAACGCTATTCA
+
+2*.%B7DF/'03%:9?<+8"!%!.<336EEEAG'D!'D,)*3$,761F(F8;?<$0F4$!?&G'B"//
@r9830
TGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATCTGGATTTGTTCNGAACGCTCGGTTGCCGCCGGGCGTTTTTTATTGGTGAGAATCGCAGCAACTTGGCGCGCCAATCGAGCCATGTCGTCGTCAACGACCCCCCATTCANGAACAGCAAGCAGCATTGAGAACTTTGGAATCCAGTCCCTCTTCCACCTGCTGATCTGCNACTTATCAAC
+
?79"*"(0(H6>BF)=D(G4@+9+/>*:E)1E+0*D/)$,=.!A84?4F!BH7DC19&'=5'3&5'4(B!D5';AB2$-5$'#8G%%/;>G&-3?5@5C4C5*+*!D7::B"G?7?99"20HH+#&%D?#-&:B@G#%B)3>/0,&*E6*>(='FE<=8@.+>).E@5*:/'%$E@(?.59)?!B&07'=B15)6CFA/:-*B)"92%?502,&A;$C;G/;20"<=!"*G:$(A3!G?0F,?96<"F9,CH9!?G+&
@r9831
AGTTGTAGTCCTGAACGAAAACCCCCCGCCATTGGCACATTGGCAGCTAATCCGGAATCGCACTTACTGCCAATGCTTCGTTTCGTATCACACACCCCAAAGCCTTCTGCTTTGAATGCTGCCCTTCTTCAGGGCTTAATTTTTAAGAGCGTCACCTTCATGGTGGTCAGTGCGTCCTNCTGATGTGCTCAGTATCACCGCCAGTGGNATTTATGTCAACACCGCCAG
+
@+/8,EAF<?0(B20'H+&6@*$5B:%>54!=@:G%DB5-B1C+.(#A:%>+C;20E&/9!86+0!F'75;14!/27B@.,4@<-6(+>.?@?.15,3F#B7(*:H7C47;2:!70D;@*F:.+B;F653G2)-D=;99?1"B@>7++@<@6A&1:,34!#%6.039H"1(!.44'9'8'&.?5HBBD+11**;)<1%7%,/#70:#6$$>H4$4)5/@AC38&13CG
@r9832
NGATATCAGGTGCTGGCGCGATGGGACACACCGAAGGTGGTGAAGGG
+
%/"%;"G!-9>D?646<!&E.-+G+G,;;=<;3.,@,;4#$%<H#*1
@r9833
CGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGT
+
1D:>$4%%;H.0.,#',21$*/(=A!1!,@#$>37*<>"%@;/?D%<4
@r9834
ANGAAACTCTTTCGTAAAAGTTATAAGGAAATATAGTTCTACCGCAACGTTTCAGCAGCAACAGTCAGAATTTATTGAAGCAAATCTGAAACCTATTATAGATTTGAATGACTTCCCCAATTATTGGNAAAGAGTTA
+
)"?D9"96*&*0;G*#&#HF)C-'3A*#;H/#+&'E></'0-1!'2,.!GCD(;5=5&!$(:3D-$*5-!%D#G(8628&!F',3#=8.5(/D5F#;063*F5D(;*<7"0=#(?$=;8*'DG>3-+&93*D)&"C;
@r9835
NNATACTNGCTCAGTTTGTCCGTGTCCTCCATGCTGAGGCCAATACCCGCGACATAATGTTTGCCGTCTTT
+
'##!!%*'+$(("%)''(%"#)("!*!#%'!)%**()&*"''$$*+(%))&"!(&!*("%)%#'#'&&"*#
@r9836
GCGCCAGTTTCAGGGCAAAACTCANCTTACCGTCGAACACTTTCCCGCAGAAACAGGCTCTGCGGGCCCGGCGTCCTCTGTCTGNTCAGGGGC
+
$.@!HC%2-GEC1G7DFBH?8)77G$"1"H53H&CA/BF#9<!$E5?3!2&!?'%HB$10+="H>5(->'02=:"9B!:)'31#0'E77@!'*
@r9837
TCGTTGAAGCATACGGAAATCAGACAGAAGTAGCACGCAGACTGAAATGTAGTCNCGGTACGGTCAGAAAATACGTTGATGATAAAGACGGGAAAATGCNCGCCATCGTCAACGACGTTCTCATGGTTCATCGCGGATGGAGTGAAAGAGATGCGCTATTACGAAAAAATTGATGGCAGCAAATA
+
.D:1';#C2/"*@@,(C$0>.=587/79!%,D6><H#;.8,<GG2"/?,,3).+7=';+EC1#D/9",>==%05:"/%$>C(67GH9%+!?$G#C%1(D&/3=>)H4)55*-,4"3B?3D?//1,93B:#E.2B0<D+%@G;)"CH09%;5.3')B0+*3:-32"+6DD3>?<+2*,-(1,C85'
@r9838
ATTTGTTTTGGTAAAGAGAAAAGTTTTTCCATCGNTTTTATGAATATACAAATAATTGGAGCCAACCTGCAGGTGATGATTATCAGCCAGCAGAGAATTAAGGAAAACAGACAGGTTTATTGAGCGCTTATCTTTCCCTTTATTTTTGCTGCG
+
1A+=2B9D!-;@$HH3.(DG6>$+'(:&5-G45<..<!-9A7G>/B@D<>6F<D@7)+$6A<!CC9$30B,D'9DH?;*-7,>"8G,?"+G9C)9/@:AG<*?CD$,6>@&D*?B@B%2:<('E?<&:@1D&H*&,'F*6@$<3?&/06;=FD
@r9839
CCGTCAGGCGAGCCAGATGTTTCTGTGCTGGCTGGAAGAGGCCATCGTTCGCCGCGTGGTGACGTTACCTTCAAAAGCGCGCTTCAGTTTTCAGGAAGCCCGCAGTGCCTGGGGGAACTGCGACTGGATAGGCTCCGGTCGTATGGCCATCGATGGTCTGAAAGAAGTTCAGGAAGCGGTGATGCTGATAGAAGCCGGACTGAGTACCTACGAGAAAGAGTGCGCAAAACGCGGTGACGACTATCAGGAAATTTTTGCCCAGCAGGTCCGTCAAACGATGGAGCGCCGTGCAGCCGGTCTTAAACCGCCCGCCTGGGCGGCTGCAGCATTT
+
7:7%57'C@$A4+C-")?>(3+#D;-<-:E?38'4;G+<#G:97/$@8$,H,3F1,F<!61@#*!?CFA'5F8/#5H(/!<5!$80%F"D(A>(3#=(D+++BF)<%1'!2!*<30D6<$/1C$E-$5#,$>$E:4H#$$&$G"%-D7(HC%H1)&>6680@%&(145.A3#('8+5)))=G9B,/C"6C>:56A4&-6((A5G/A33-&*:0)?:*CFC'47=1F194"&(H80).&6F/,G=;/+-!#F65%&#H*G0)(>,0F07*9:;!-<;&-)*$CB!#)-GC@4"<(-3<*7<7';'&&'F<)6<C#C6F!3B(*B"G7&+E./
@r9840
CAGGTGGCCTGAACNAACAGTTCACCGTTAAAGGCGTGCATGGCC
+
;;0-;/;=(E.9(0>(*B&7!2#:47%<,*'AA'7/?(?%4A?.;
@r9841
GCNAGATNCCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGAC
+
''%%!&($+%#(###!!'!"++&'(''&+('%%#$""#!!'()!"!)+(#)"+$'#!"+(#
@r9842
CTGGTAGTGACGCGCCCAGCTCTGAGCCTCAAGACGATNCTGAATGTAATAAGCGTTCATGGCTGAACTCCTGAAATAGCTGTGAA
+
H7)%C2GAG*;$!"%?,B/D4F-""D-*BB%"5='H4'A1#?2*#70F-+>+3+,4!F/)84.9E&)"*#49@E61$-$FDH--#H
@r9843
GACCGGCAGTGAGCAGAACTGGCGCAGCNTCACCCGTTCCGTGCTGTNCATGATGACAGAAATTCTGATTAAGCAGGCAATGGTGGGGATTGTCGGGAGTATCGGCAGCGCCATTGGCGGAGCTGTTGGTGGCGGCGCATCCGCGTCAGGCGGTANAGCCATTCAGGCCGCTG
+
+"&$+"%$*&'$&#!!'#$!**)$)'*+&*'+(*++""%&+')###+!*&$(#%+&%'#&+"+$&'+"&%'$'!%#$)$+&%&"!'!'+('#"'%('$*$(#'!!)+&$%**((#!!*%''"%*)+*+$*$&'%+$&*'%&+%)+$)'")*&*(#(**'$)'$+"$#$)+)#!
@r9844
NNGTTNNAGCNCGGCNCNTTTATACNCGNCATNTNGCNANCCNCNNCTTNNTTNNTNNNNTGGN
+
##"!!#$##$$$#$"!!!!$!""!!!$#!#"$!$##$!###"""$"#$$$"#$!#"!""##$$"
@r9845
GTTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGATAATCGATGCACATTGATTGCTAGCGAAAATGCAAGAGCAAAGACGAAAACATGCCACACATGAGGAATACCGATTCTCTCATNAACAT
+
&+*$#"&$*&+*'")"('&*"('%'"(%'##!&!$'"$)($&$&%&()*("'!#(+)%%*$'$&+&*%+#%*+%&"')&!)(('#(*)%++!"&)#$++)&+)+#&%''""$!"$#$+#$&+%"%#&$"#&*'"%#(+&#($)%$&'$(&++
@r9846
ACGTCTCTCGTCAGGTTGAATGGCATGGTCGCTGGCTGGATGCAGAAAGCTGGAAGTGTGTGTTTACCGCAGCATTCAAGCAGCAGGATGTTGTTCCTAACCTTGCCGGGAATGGCTTTGTGGTAATAGGCCAGTCAACCAGCAGGATGCGTGTAGGCGAATTTGCNGAGC
+
E,4:"D6%.$/6*=;$%..*$?H%."+%/85E)!8C9=:<A""%<37;3)$?)-*;8F46C1<B3D#>=H"92A%C>$+6=<A;8$-79'%-5&/;,9-H#4!.@;7=+F-"'/;B(0)6H#35(E@=)5BF59E3)26.79HEC%023"9C&+E#.3B.,*8F>>&;;7.
@r9847
GGTGGTGAAAGGGCAGAGCACCACGCTGACCGTGGCCTTCCAGCCGGAGGGCGTAACCGACAAGAGCTTTCGTGCGGTGTCTGCGGATAAAACAAAAGCCACCGTGTCGGTCAGTGGTATGACCATCACCGCGAACGGCGTTGCTGCAGGCAAGGTCAACATTCCGGTTGTATNC
+
@'/!*4/*G,A4!!-:B05'4&#2E/A&>2DF22,7F<D/FCC3!4&3#5.0?=36C*(8,8@0:'C-?&%B#G)!E365"0&(5($"193A-%7'4,0!5"6@)"@2?$(=0D"+01F1!(:/25</?(#0+-:'0+6A;9-C4'H0F;;1(C+&/A/<4,7@@6&52#CA#,H
@r9848
TTTAGTGATGATGGGTAAAGGATGCTGNTTGCCGTTCCGGCA
+
,*G()"3'H-A2>.*+,'(0$:?-7DF23991F:!B3F1H@A
@r9849
TATGCTCTCTTTTCTGACGTTAGTCTCCGACGGCAGGCTTCAATGA
+
/>-:@"-8H#&;(D!7>&#!&),'5&%'7=<$=-G*&>0'%$G$'D
@r9850
TTCAGTCAGCACCGCTGATGCTGCTGGCTGACCCTGATGAGTTCGTGTCCGTACAACTGGCGTAATCATGGCCCTTCGGGGCCATTGTTTCTCTGTGGAGGAGTCCATGACGAAAGATGAACTGATTGCCCGTCTCCGCTCGCTGGGTGAACAACTNAACCGTGATGTCAGCCTGACGGGGACGAAAGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGAC
+
26$3=>:0",5*.<G3)$C;,+A?161>'7B-1/::(CF+8F?2B6$,)!987.-0:&.#9-.7A4;$".FCG&%A*?/.=B!E/@="%4>#<)=.?:62&D8@2F<:H@9?7(G;.)!AF5!';E"@,G1D8&2?9C&3@E3(.85EA(6>E--,"3,A>4%-576$0;F696,=0(=B:<7:201DD=8.H98329/2<";7F(9)F%3*B4*"4-)7<)5A!'5$!21:C+/
@r9851
GTGCACGATTTAGAGGTCTACCGCCCATGACAGGAAGTTGTTTTACTGGTTCAGGGATAGCCTCACCACGGTTAATTCTCGCAG
+
>%G8/24;BDF)7$DGH@@$&H%13>)"028-"8"8H#*%<=(/:*$D!&0".F#?8BF9D))0G:&?C'@HFE!;@@;*:C)@
@r9852
GATGACGCATCCTCACGATAATATCCGGGTAGGCGCAATCACTTTCGTCTACTCCGTTA
+
B?@H>*(#AG*,5'G6D30-A"0/.&=+@C*F?BB*;47&!$D>=7*5!D!A094(;C8
@r9853
TTCGATTTCGTCTACTGCTTCCTGCCCGACGCGGCTAATCAGTTCGACGCGATACGGAACGNGATTTCCGCTTTTGTGCTGGTTGCACACCACGCATTGATTGTGAATATTGCGTTCATNAAATCGGAGTTGAGGTGCCGCAGCAGTTGTCCGGTAATGTCCGGCATCCCACTGAGCAGACGTGAGCGTTC
+
A"41-"4&/C#2*,/!(>H7=@2A*%.49!D"F;'):;<64/*.4E83)?C4=A6=)*!;4#(>G.$-.#.1.0/8+87.%F9@!&2-))>=/;7%3E4&"F$AE#C/9-1CC/);@$$3C,AD/%E=/!F03%G!3#&:/;!4"?%-=H@(>B5::6*14..+$+?A&CC5':#BA%4(E64?)(#C2>1
@r9854
AAATGGTTATACGGTATGGGANCCAAAGGATATTCAGGCGCGAATGCCTGTNCTGAAGCCATTTATCGATATGGTAAAGAAATATGGCACTCCATACGTCGGCGGCGCGTTCTGCACTGACAGATTAAAACTCGTTCCCTTCACCAAATACTGTGATGACCATTTCGGGCGAGGGAATTACACCACGTGGATTGGCATCAGAGCTGATGAACCNAAGCGGCTAAAGCNAAAGCCTGGAATCAGATATCTTGCTG
+
+%**$"'*#*'%++$&!*$#'%!%)&&)++$$&%"&%&$)+&"!$!#$!$$('&"+"&&$")!+('!"*)!#)+')('#(&)!%%#((#""")$)"%(($%($$""$"+!#'+(!!*"+!&)+*+)*'++'"*%*(!)%%"!"")"!)#)%*%(&+!&$!'((''%&*+!#(!()$$&!(&%!!"*+*'%%*"%"&)$+!'"'!%"(#$&"'+!+))%+!+*%&($'(&*)'%*"$"()$('&!(&"#&"$)!'
@r9855
TTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTG
+
-#*?*G2/1$$*9;002/'-=DD#$?%+7%)A6HC-9%E=+F:.C@;>76A(!7!BBF/7<7<''6*85(%E!1G6=*C.51C:.*E;/#4&'("%68C!5F6:;.37*;E.9G
@r9856
NCCGCGTTTTGCGCACTCTTTCTCGTAGGTACTCAGTCCGGCTTCTATCAGCATCACCGCTTCC
+
+%*"#+$'**(&&&$)%%!(%%#)#+*$$'*$&&##$)!%%)")(*+*#&")&)##!&#+")"$
@r9857
NGGCTGGGCTCTGCTAACACGTTGCTCATAGGAGNTATGTT
+
",?@B@2?6?A'-F+&H$?,?(D&:E2#%2B?955<F."2C
@r9858
GTGGCAATCCGGTCAGCGTGGAGGTTCAGTCCGTCACCGACGGCGT
+
&8'<?BG&G246"5C)0>A#</F2H@/==A@10D4B1&0)!02G1F
@r9859
CTTAGTTCTCTGCTGGCTGATAATCATNACCTGCAGGTTGGCTCCAATTATTTGTATATTCATAAAATCGATGGAAAAACTTTTCTCTTTACCAAAACAAATGACAAGAGTCTGG
+
GA1$&;E11(D/0*)-*"8E74%)F28+>>*A56+>G9F"F":C(E>>.91.4.'C<).A'(*&-'&83/;E535C?9/C2HH#:B")7+&<","/$$2/H284("FH<;7BH"G
@r9860
CCCGCCACATCCANCGACTTTTCACGGTAGTTTTTTGCCGCTTTACCGCCCAGGCACCAGAAGCCACGCCCATTAGTGAAACGCTTCATGGNGAGCGTGTTATCCCGGTGCTTTTNGCCATACCACGGGGCCAGCGCCAGCAGCGACGGAATATCACNAATAGGCGGCTCAACGTGGGTTTTCATAAAGTTCTCGGCATCACCATCCGTCGGCAACCAGATGAGGGTGTTGCGCTGCTTATGCTCTATAAAGTAGGCATAAACACCCAGCAGCATTTTGGAATAACCGACACGGGCAGACTTCAC
+
?=$=-$E%4!"5%/B70B-5?.7;=1'7<#C9H&".<.03=D$#='#!5)8#=8-.H<$7/!A!%=,#(7=&*%#F6.?"*-8&GG:0"7;.&=9E%/.&EA('F7'B,*%F5HA(AG'4:+',@>9F*8B#4".@E<,6"@F-*G."+'1:("6';F)+.2?,1E!($6B%1F6=B<4BE)4&.A?)C,,#B'#15/3@=2E'0&F(F6HC1$#?F<(:$AG6(')C<6>.$)B8!C"6)A;%/;>5.*#<'%=/0'30@'>3,AC"#+(75.:C:)/3>5"B&#G<3)9AE/3GB:5&4H67E
@r9861
CTTCTTCCTCGTGCATCGAGCTATTCGGATCGCTCANCAGTTCTGCGCAGCAGTGCTCACACACGTGAACTT
+
F+-.CF'-@D/,>1F(9)**E9<>G;.D<&&!(=&0F#H:<4(9/%.A??C;%>G:701<+4"(&$!63%<$
@r9862
GTGTCCTGAATATAACTCAATGTTGGCCTGTATAGCTTCAGTGATTGCGATTCGCCTGTCTCTGCCTAATCCAAACTCTTTACCCGGCCTTGGGT
+
?F@?.@9'7E76$$$2=1:=!3.$$,.+$0"FB%@299%3?96G+1.70@%2;+$!,3CBB:%@)1>&G2+FA7B1,-;)DA2=,".!C+>D%!5
@r9863
TGAACCGTGATGTCAGCCTGACGGGGACGAANGAAGAACTGGCGCTCCGTGTGGCAGAGCTGAAAGAGGAGCTTGATGACACGGATGAAACTGCCGGTCAGGACACCCCTCTCAGCCGGGAAAATGTGCTGACCGGACATGAAAATGAGGTGGGATCAGC
+
A27'*HA7#1B4;1G-1)8':--H.(&/=:=>!G75.>)&41&5HD7B?1>)BB9D2,01&93?4G.-$4.*G#,,:D8+$-43=A;<6#>.;'H82BB*A4A!40:73"CGH2?G>F./((G>8?)6#<=+)G'B'.!'&D9/9F9DB0,E.DG5-E/C
@r9864
TACCAGGGAAGAACGGGAAGGAAAGATGAGCACGAACCTGNTTTTTAAGGAGTGTCGCCAGAG
+
"5C)/6C!>&.H,8!1E9!2C0&7+1>$9E90=1-+('/#>>F),"0(.'3G=CF;G!>A#">
@r9865
GACAAACTCACCACGGTGAACAATCCCCGCTGGCTCATATTTGCC
+
AF"CG6%G8=>HE27F>?"4>*::,A6:D0<7=@&72'0A4H(E4
@r9866
NANTTTCCTCACCGATGGTCAGCGTGTCTCCACGCCGCAGCTGCCGCACCTCATCAGTCCGGACAAACAGGGACGGGCTG
+
(("&+!!+#*%'#%&%**&*'!+*!!&"$)&"#"(*)#"*)*)!"%%$!%(&+%'&*"%!!$!$#*+($#!!**$%#(*%
@r9867
TNCGTNGCTNGNCGNCAACGAGATGCCACGATGCCTCATCACTGTTGCAAACAGCCACAAAGCCAGCCGGAATATCTGGCGGTGNAATATCGGTACTGTTTGCAGGCAGACCGGTATGAGGCGGAATATATGCGTCACCTTCACCAATAAATTCATTAGTTCCGGCCAGCANATTATAAA
+
&%('(!)!$#'&)!$***+!#'+(&+('*(*+"%'&*!+(&%!*%#"*)%"*%'$&&"!)'"#)'(*'")'&*+%+$!)!#$$$''%(*#'$#&+$!%$*))*%'#(!%'+$#(''((*+*+("#&#"')!$"$%&&"+%))#$(&'%'*%)#('$%'*#)(!(*++(*&#("+"#)!++
@r9868
GNTTTGCATCTTAATGCGTTTTCTTAGCTTAAATCGCTTATATCTGGCGCTGGCAATAGCTGAGAATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACGAACACATGCCACACATGAGGAATACCGATTCTCTCATTAACAT
+
&#*4GA!48;;H0%@.!BA$A>+&AD'E6<D9"6;#!F5';&6C<)1?*;4A17G0<*'$68';)E4)*/!(;E,H@;2+-;5F+=9E!74-4HDB4+'8&;;C283$/;:%D@">71)/>D8$&D.%!-7/<,D7E'.8%.=!%".CH$'D
@r9869
ATGCCTGCGTCATCCGCCAGCAGGAGCTGGACTTTACTGATGCCCGTTAT
+
'C;F-?/97#+.-$#*%H+E5=H#>=>-E=@H:#+*+:69,8-&B,$)@.
@r9870
NTATTAGATTTTGCATAAAAANCGGACGACATAATACTGTAAAACACAACATATGCAGTCACTATGAATCAACTACTTAGATGGTATTAGTGACCTGTAACAGAGCATTAGCGCAAGGTGATTTTTGTCTTCTTGCGCTAATTTTTTGTCATCAAANCTGTCGCANTCC
+
&"+!&*'!(!)$+)'))"$#!++%%*!&&')&!+!#$#*%+"+%+!)!*'#(*)**"&"&!*!()*"*(!*!'%%+'(%!**+**)(')(($%(%$)$*)%&!*'+$+)!#&$#%$(+%#+&&*$#!!"$+&&(*'+$%%+"%#%$++*%*)+'%%)!")&##&&+*++
@r9871
ATATACCGGCCTGTCCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATTGATGCCGGACTGGCTGATGAACTTGTTAACAGCACCGATGCGATCACCGTCATGCGTGATGCACTGGATGCACGTAAATCCCGTCTCTCAGGATGGCGAATG
+
HC#E,@EC+:%@*F?99A(79'0*4'5(%8;'&,.G:C'%;$?1D37-859*G8,AD-E'CF4B81'CD/(?0!G!@8<.?$#5;/G1C(:*"H.5<$,=0(9"5()!)*5!8/./6;#H.(H'1(;H7)A=.&58!H*22BE);*!@DCC#E7(=($'<01.?4'6'1&:#
@r9872
GNAAAATNTGCAGCGGACAAATTTAAGTTTGATCCGCTGTTTCTGCGTCTCTTTTTCCGTGAGAGCTATCCCTTCACCACGGAGAAAGNCTATCTCTCACAAATTCCGGGACTGGTAAACATGGCGNTGTACGTTTCGCCGATCGTTTCCGGTGAGGTTATCC
+
*!!*()&!"+"*$$()*"$)#(""!)$)&$#!+((*!"!(&$+%%$*)+!&++)%$*+)+)'+''$'((#!%&"+++#!!()'#')$#+$%!+"+$!'+*"+*(+"!*($%!#&)*#*()#*"(+)#('"!%)'*$*%!)*#$$!+')*+$!!*#()*!%)*!
@r9873
TTTTGTGCAAGTCTGACTNACTTTTTTATACCAATGTTTAACATACTTTCATTTNTAATAAACTCAATGTCATTTTCTTCAATGTAAGATNAAANAAGAGTAGCCTTTGCCTCGCTATACATTTCTAA
+
>.-6C&&<)BH&+,E:A.AB1*!F=;H):-$D24(G%@H!.502+EG=A95-1:=@'H7E"=3=E9$(92A+22E501G0<GH4C*?!D2&='C(/0@&D5/&A7?H(B.#5-CCF(H?<+4;8<G''
@r9874
NGAGNANGNGNNAGTGNTTGCGCCTACCCGGATATTATCGTGAGGATGCGT
+
!(%$#*"*!"%!)(%&#+$$'&!&*'"$#$"(&"*#(#+"*&"'(#!&"(+
@r9875
AGAAACTCAAAGACCTGCGAAATAGCAGAAGTGAGGCCGCATGACGTTCTCAGTAAAAACCATTCCAGACATGCTCGTTGAAGCATACGGAAATCAGACAG
+
&DEA)0;H):B.AC67!GH#=%H;3$:=-)&<0=(',3:=.H1B,,//#F>#.6A9B.@+*!AE!E#&;-+72<3D.H!/H'/&/)>0ED3%4%;+8235!
@r9876
TTGATCGCCAGATAGTGGTGCTTCCGCTGACGTCGTTCGCGGAAGTAAGCGTACTGTCAGCTGCAGGACAACGTATTCGATGTGTTA
+
:,(E)?'H4=$:471,*9+8>"?'9F<,?;6>2.7#*%;17!E4)H+DG@3B29*6/+;H$&!?"F5H#&4G#H!%9?5<?(:<;E(
@r9877
GCTGCTGAAACGTTGCGGTTGAACTATATTTCCTTATAACTTTTACGAANGAGTTTCTTTGAGTAATCACTTCACTC
+
7=A)-;;+30$;,.FH?."A'"<=35%C/<4'(B+4B@%'@A4C2,>C+4*/G''2HH5:5"<8D%..B?&)#-@43
@r9878
ANTGGAAATCAAACGCGCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGA
+
+"%*+!)'#"'#'"&%+%(&'''**%+"*$+*'+!*+*&)"&"')*#)$*+&%&'(!($!('"&)!"*+%$!'%#("++!!%&%%#&(!*)(&+"&++'"$(!
@r9879
ATGCAATTATTGTGAGCAATACACACGCGCTTCCAGCGGCAGTATAAATGCCTAAAGTAATAAAACCGAGCAATCCATTTACGAATGTTTGCTGGG
+
3+,?#:F3,.(A0%@45+<*75)45>+AAE=E2;C+;.+&@'1#D2,$A8F-?#=?596#C,%=*,<.>3=(:'/G1:=D6@54??"6D#.#&;&/
@r9880
NTATTTCGCTTGAATTTGAATCAATTACTCCAAACCGCAAGAACAGTAACATNTATTATTCAAAAAAACAAAAACCAGATTATAGGATATGACATTTGGTATAACAATAATGTTATTGAAAAATGGAAAAATGATCCATTAATGGCTTGGGCTAAAAATTCTCGCAATACGATAGAAAAACAAGGCGATTTAGAAATGTATAGCGAGGCAAAGGCTACTCTTATTTCATCTTACATTGAAGAAAATGNCAT
+
)+#!"+!+#'!(%#"+(+"&'*)!!$%*'!*(#%))%(%$)')))$&!!(*+)!)(#$#*("!(*#'*)+'!(""&'"!#*'*#!+%&'#!*$"!!*(!!'%+#*$%*!+)"&%""!)+&)++&)(#+$!)*+$&''*'*)((&'*'+$"(+%+$$$!(*!)*'&%#(*!%%**'!*!++"!'(&*"&'!$$'++(**+&()*$**)+!##'"%!(#(&"'!&'(+*(*+')!$#(+%&*"+"$&&%#(")
@r9881
CATGGCTTTATGACGTAACATCCGTTTGGGATGCGACTGCCACGGCCCCGTG
+
*H@<*2+#!8@2E62A0&;G@24B6EA?1F/G&+)=.F2":F3%A6H4(&BH
@r9882
TGTATTCCGGACGGTACGTGGAAAACGGCGTCAAANAGAACTTCCTGCCGGACAACACGATGGTGCTGG
+
B1485C>/+4>4!H=/;#7)@*,F7$"HA'%327$(7!9?#+;G*@6'(&/;#;.#6<A*C=FD?D9A.
@r9883
NNTCCTGTCACCCTTTGAGGTGGTTTCCACCAGTGCCTATACACCGAAGGTAAAGCGCAGACGGTCGATGTTTGCAGACGTAATGGTGCGGGTGATCGGCGTGTCATATTTCACTTCCGTACCCNGCACCGTCTCGGAGCCGGAG
+
#%H8<+6:G81437?.A*<4?5-1576HD.?1-G16%/#,<71A4;,H'"0*63-8(+8&':;2',>":(707E(.-H:87?HA%E=>4635G?3&8C4;>!=<419;7A''/6B70?C?:<+1H#(H"(53C3H<54#E@=?A"
@r9884
GCGGATCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGC
+
3-<'@&B&3+-0C;E%=2@6.,>74>47=&"H2B=G8>2&)81#(#<-05D-$
@r9885
NTGNCAGNCCTCNTGNAATAGCTGTGAAAATATCGCCCGCGAAATGCCGGGCTGATTAGGAAAACAGGANAGGGGGTTAGTGAATGCTTTTGCTTGATCTCA
+
#)(!&)#""(&%&*$!'+"(*$*!"'"!)%)$#*&+&#+""%$%!!#%+')!$$)#)%'(!&%)&'#(++)"!#+""*!%*'(*"#'&$++"#+"$%%()%(
@r9886
GGTTTGATATTGATACTGGCGGCTATCCAGTACAGCGCCGTACCAAGATAACGCGTGCTGGTTTCAACCTGTCTGATATCCGCAATCTGCTTTTCCGAGAACCAGAACTCAAACTGTACCGTCGGGTCATAAACGGCAAGATGCGGCGTGGCGGTTATCTGAAAATAGCCCGGCGTCAGCTCAATCCTCGACGGTGCTGCCGGTGCGGCAATCCGGAACGATACCGACGCCGGATCGCCCTGCTGCCCCCACGCATTNACCGCCCGGACTGTCAGCCTGTAGTTCCCCAGCGCCAGTTGCGTGAAGCGGTANGTGGTTTCCGTCGTCCGGGCCGTGCTGACCAGCCGCTCACTGCCGTCGTCCGCTGT
+
?)F@1&D-+<F364!H/F02B.:'&;153A,0<6)4=->HF%&E,7!8#G)&</<9(5(:92F'9D&GFE26+E+2?-A9B/0>(6DG)E=#E3E3;;A937A'."?G-&!1F"5B7F(,&=7;!6#969/&$&0H,E4#.-E73B48.".<$./:C6=*6+27.>AE(<$$:7CE"-,$)4930#=&:2>-?-#2-.)#3A1/202'526-ABBF;3>*0%726?:3H99,=15#)4*?;>6?"9<>',0C:A-81!,*.5>,?;",#-86@(D.724H'+-%#>A:EE:6@H7D32&?EA<5?73%C2-;6672'F4:'0>73/-B.59>1C!20;0(1D3G8%>.:;8?'3-<@!*=(&?35)?:
@r9887
CATTTATCATGCAGCCCTGTCTCCCCATCTCGCTTTCCACCCCAGAGCCAGTCTCGCTTCGTCTGACCACTTAACGCCACGCTCTGTACCGAATGCCTGTATAAGCTCTAATAGCTCCGCAAATTCGCCTACNCGCATCCTGCTGGTTGACTGGCCT
+
G1,!A3BD.1@2A-83<9+$DE%%1F+5F*!.,"@),(;09D.B0*EC.G3.HBC12&)/(5#?!7+-=./-!A;224)GH:6$4&$5C*5E=2B?7EB('2C6";7D<("+'1A9*?8)18<5=-3-EB'/H"/>!7A?:&B+-*2'',)5?%>,/
@r9888
TGCCGGACGGCTTTGGCGGCACGGAGCCGCGCATNACCTGTAATGCGTACCTGACCACACAGCGTAAGGCGTGGGATGTGCTCAGCGATTTCTGCTCGGCGAT
+
>B:"74,C4:''.*$.&C"->7>B8-"G86%*53F)75"/)8:,:(2,.DH4+(56<BB5@BBAH<#.5!H9H/>=8$H24=;0@1-+G)<+.!G-F"7<1B'
@r9889
GGATTTCTCCTGTGCAGACAGCTGGCGACGTTGCGCCGCCTCCTCCAGTAC
+
@)2+?-$(#%E'?*7D4G>/(;>AA8*$@<=:8'-!H:D%!/8G950:A,!
@r9890
GGGCGATAATGCCGTTGTAACCGNTCATCCCCGAGTACGGCTGCAGCGCCCGGGTCCGGCTGACCAGCGTGCCGGACACCGGCAGCACGGCGATGCCGTTCATGACCTGATAACTGCGGGCCTGTCGTGGTCCGTCATCATCACCGGATAATGCCAGCGTCGCGNGTGCCTCCTGGGCAGTCAGGCTGTCGCCGGACACCGCATC
+
GC9&(&B1@$E%AE0.$63?$&3"FH$94$5;1.7@D4%&G%87E,//7:31'+8>(/:*C*G*..&?E0;&;%A0>&$$2E7$E(,;55*)15+<B+7=4!:ED#5B!!#'+G&.31D15CC*B;0$="%09%G<<!)&C(.$>?!/5HH2B".,C#"#2,>:4/E>.==3<2CFE7>"=.<!@.#A-;=;?$+(#0G=1'&0)
@r9891
TAGGGACAGTGGCGTACAGTCATAGATGGTCGGTGGGAGNTGGTACAAATTCTCTCATGCAAAAAATATGTAAAATCGGTAGCAACTGGAAATCATTCAACACCCGCACTATCGGAAGT
+
B5D+'E+)D9#F$.;7A9#)>F9872F0AA)?0:&;,6)=A-!3356B63&9!=><5),265*,E!#)H6*G=A6'?)5H$A8.B&%5=@%35;0#35-HGF&D:H-,E-20!@F2C''
@r9892
NNTGAAGAAGCACCGCGAAACGGTAACGCTGATGGGATTCACACCGACTCATTTAAGCCTGGCANTCGGCATGTTAAACGGCGTCTTTAAGGAACGATGAACATGAAAAGCA
+
!",/#$=1A;1/?=4*(1B?4@:BB<?$E/27%3@@%A<9=<B22#.@E4B07E9D)6&B(@;34"@*)$@:&D(>5&(%@5@8CB1CC#1A(1.7HA?3G7B:E23<<.$*
@r9893
GACCTAACGCGGTGACGAGTGCGGTTATAGCGGTCCGGCTGTCGNGGATGAANATGACCAGCCAACGTCCGATATCACGAAGGATAAATGCAGCAAANGCCTGA
+
1CH3,D(E%B9#E?AGG,!@0H*0+E5$(%&@!534,?.:(&%>>23B+#5HB.-:@6<0;&'6<)'(B/GC86>&A?*25#?+'3E%F")!?@/&&$):'#2,
@r9894
ANAGTCTGTAGTGTCAGATGATGACCGTACTCAAACATCGGGTTGANTATTATCTTACTGTTTCTTTACATAAACATTGCTGATACCGTTTAGCTGAAACGNCATNCATTGCAAGGAGTTTATAAATGAGTATCAATGAGTTAGAGTCTGAGCAAAAAGATTGGGCGTTATCAATGTTGTGCAGATCCGGTGTCTTGTCTCCATGNAGACATCACGAAGGTGTTTATGTAG
+
&(+%%"($"(*+!"&&'%!'***(+!%#))*!+%%!")$+!)(&!#)&#"#&$())&&$%#"&*'(*$('*#($!%#)'##')%'!%+#))+)(&*%)$%#+)'+')&$"#&*'&''!#*%*'&&('!'!%+&+(#(''"##&((&'&&'+&&&)"'$!#''*(#%#%+&'!##%(%!(+)'!!*(##*%!"&#*%)%!%*+"''"*'$*(')&#"")$%*"*#&++#%')
@r9895
NNTATCAGNTACCGNTTGCCGGGCGGGACGTCAGCACGTCNGGGTTAACGGCGC
+
''()*(*)''$"!)"+%+"&$#(#'+#%+&!"(&*)"+)#&")$#&*+(!('"+
@r9896
CGATGCCTTGTTCCTTTGCCGCGAGACTGGCGGCCAACAGGTCATGTTTTTCTGGCATCTTCATGTCTTACCCCCAATAAGGGGATTTGCTCTATTTAATTAGGAATAAGGTCGATTACTGATAGAACAAATCCAGNCTACTGTGTTTAGTAATCAGATTTGTTCGTGACCGATATGCACGGGCAAAACGGCAGGAGGTTGTTAGCGC
+
<&>F!,)";/3H/!,2F%C7&BA4'G?G7;;$69'3+43?F8"=<2=1)*.+.D4)!B@*::C@>DA"4C!=0'-.+5/4'5$7&+<BFD#F<HE=G!2(/@B;$,/;)8ACGG>#6/B2>C:(</H))+,B4"?7,2&7D(!"G&-)&"?2>*02"C/F=?.:(,<5!#8FD2'%"6&;B:C6,;$<><>/+*EC3+G/;7CD14?/
@r9897
CAGAGCGTCATACAGCGGCTTAAGAGTGCGTGAACNGGTGGGTTGGGTAAGGTTTGGGATCCCTAGCATCGTCACAGCGCGATATGCTGCGCTTGCTGGCATCCTTGAATAGCCGACGCCTTTGCA
+
*)">>=6".+C92<*C<=,*5)=D"*C;,BG/'C4GC.>>E@2>F$83;5C341B@G;=;F>4)+G1H*=;0DB9;,*4G1BC9<<,<6%6=#<B$CF*%8:;</@3474*(H@B9,::-0E;-8!
@r9898
NNCANNNNANNNGGNAGNNGCNTNTNNCNCATTCNTNCTNNNANTGGNNGNNCNCNCTANNGCNACANCCTTNCNNNAGAGGGCNGGGTCCNNNANTCTCNCNNNCNNNATNNNNCGNATACCGNCANNTGCGCTGNCNANCANTTTNNNNNTACNNGNANNNNAATNAGCN
+
!#$$"!#"#!!!#""!"!!"$#"$$$$#!$#$$"##!"$"#!$##!!$"#"!""!#$!!#$"$#$"#!""!""$$$!#"$#$#!#""!$!#!#!"#$$$#"#!""$$!#$!!$$$!$"$$###$#!$!!"!$#$$#""!"!$##$"$!#""!""!#"$#"#"#$#!!"$"#!
@r9899
NNNNTNNGNTAGNACTGTATCGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGCAANGAAGTCCGTGGCTATCTATCGGCTTATTAGTACTTGAAACGCTTCTTCAGAAGCCTGAAGAGCTAATCGTTCGGCGATACTATATATGCATTAATAGACTATATCGTTGGTATAAACAGTGCACCATGCAACATGANTAACAGTGGGTTATCCAAAAGGAAGCAGAAAGCTAA
+
!("%*'#*!!$"#&*''))&!+%"#&#%#)&(%$#*!!#'&(!(%*%"'!&%!%&)"%++#''#(*!")"'%"$&%%+!)("&+&&&%%*)$"#*%"%(%#$+(+&#')"'*#%!)&!$"*%#&(*'!))!')#''*&$**!+"*&*+%$!$&"")&'(+&$('!)&!!'&%#!(*('''%'!(*%'$"$(('()!#&(&)&))"')!)$+!()!''$+"$$!'++%)#*#()*'%#$%()*+''&(
@r9900
AAATTGGTTTTGTAGGTCAAAAAGAAGAAGTAAGCACTTATTCATTAATAGATAAA
+
.6#'4>"@*&DC(89C+:1>54C.6)'189&=,DA;H'E-$60B(+A7B>.'!D#;
@r9901
ACCGGACTNCTCCTGCGATCCCTTCTGATACTGTCATCAGCATTACGTCATCCTCCGTCA
+
:'<*D&F@12*AH9;5H).E;9:5.F8$%&5'*D2A##&%70A@729-H&C1=:"9/:<:
@r9902
GCATTGCNCNGNGTNTNCATTCCNNCGAGTGAATACANGGAGCAATGTCGCTCGTAANTAAACAGGAGCCG
+
!%)"))'!$#$"(('$)*%*(%%#!#+#+)"(&)&%##)!"#%*)'*&!*$''*+%%(''+**&'!$'#&+
@r9903
TCTGAGTGTGTTACAGAGGTTCGTCCGNGAACGGGCGTTTTATTATAAAACAGTGAGAGGTGAACGATGCGTAATGTGTGTATTGCCGTTGCTGTCTTTGCCGCACTTGCGGTGACAGTCACTCCGGCCCGTGCGGAAGGTGGACATGGTACGTTTACGGTGGGCTATTTTCAAGTGAAACCGGGTACATTGCCGTCGTTGTCGGGCNGGGTTACCG
+
-CFB5=A7*7?-HD*A.#HC6@*9AG%@E4F5&;!".:<".7(=:03C#E+.<CA3-770*18HF;+BG%7H$F?<@;.9F+)-+C9:&3<%&$3C0#*>8%7F;:H,19(;F?%*B&:18B'/+,>(?(!+0A>?E6D7*)*!7!.&,!'(F(@',;G4,714F<+A0?=B5,)4,9:<#(C/>9!EAH1(#H8B!>&5=C89G:74>)*>+B4:?
@r9904
TTCCTGAAGATANTAAAGAGCGTCTAAAACTGGTAGATAAGCCTAAAAATATCACTTCGACAGAAGAGTTAGTTGACTATACAGCCAAGCTTGCAGAAACGACTTTTTTAAAGGACGGTTATCACATTCAAACATTAATTTTTTATGATAAACAATTCCATCCAATTGATTTAATCAATACAACATTTGAAGATCAAGCAGATAAATATATTTTTTGGCGTTATGCAGCTGACAGAGCCAAAATAACAAAT
+
H-A>19"H>)+87"*3@H)0%BFFDB/0;7E)/F1#<A?8&::."<E5GD#'*<,40A/,4A)C41)/1(:";<EH">&!#=-,G:&F+(;,G,!);=D1B4*B&-G$AC5EG)D@*&?"6'B<B6(-<3AG8E/H:3#,GC"36/5-E;>0C/%B<AF?A-E(B4GHE1">@8,GG4G>G%+GD7?8A#.5.AC&<,?-B=-1B"((DB+%>&/HA.-E*=E@?BAC:0/>)F*7=%;0;,60&=D,@9D
@r9905
GGCAGAGGCTGCGTATAAGAAAGCAGACGACATCTGGAATCTGCGCAAGGATGATTATTTTGTTAACGATGAAGCGCGGGCNCGTTACTGGGATGAGTGAAAAGGCCCGTCTTGCGCTTGAAGCCGCCCGAAAGAAGGC
+
<=@3*+$C)8&6;&&C10>%7"88!+E7;8=AGG@H%(=36/%##,/%8&+,+$(139-9C/-*DE!%H>1GA?,HH579+87?,/F0B)>63#<FA86!>"49*?AA.B'%#/C?50&94G!=;%6&<02'E/&+-'.
@r9906
AACCGGATGCTGCAATTCAGAGCGGCAGCAAGTGGGGGACAGCAGAAGACCTGACCGCCGCAGAGTGGATGTTTGACATGGTGAAGACTATCGCACCATCAGCCAGAAAACCGAATTTTGCTGGGTGGGCTAACGATATCCGCCTGATGCGTGAACGTGACGGACGTAACCACCGCGACATGTGTGTGCTGTTCCGCTGGGCATGCCAGGACAACTTCTGGTCCGGTAACGTGCTGAGCCCGGCCAAACTCCGCGATAAGTGGACCAAACTCGAAATCA
+
=);3"A(&'481?$3184"&/7<"*6')*D*<A;AG4&+')!A"!4-E<$0C</5-?;/!4/-/--EA(,55<7D##8?G@6!(%9!5+=@6@F>FA6#>2@(;(46C)11!B5B%"EG-(B1F/F$"(31F4/4**F?7+A$<9.467:77/.E+/D<#0G?'77%C#&+*94)<**?)>&BE=A=%1A1A@=?1;?BB$*"B.&.>)BH<#,4E04("4HD3)E?9@)4/,/17E,%(88+:6.*-19=?0':+("7$E*#6B/)49@>896CF=36
@r9907
CCTCTGGCGTCACCGGGCATGGCGCGCAACTGCCTTTACGGGGATTTACAACGATTTGGTCGCCGCATCGACCTTCGTGTGAAA
+
;D+)CGB(1/,1(&.?4!<(F1":+.G1?2(!$A*335,'A5.*14@H,9/!9"4&+;D/>D!.(*:0=H#H7)E+'B<,'3-4
@r9908
GCTGAACGAGAAACGTAAAATGATATAAATATCAATATATTAAATTAGATTTTGCATAAAAAACGGACTACATAATACTGTAAAACACAACATATGCAGTCACAATGAATCAACTACTTAGATGGTATTA
+
;D%?1/D+C(2;?>!36?.F<%D;4&-$1@>'8!'=8"-'"07'D%*4:*.7"CDG0,CE@.'E:'+?5.5:E29+5GB-4DE4CDDC71>CCF9@&.(2!9#1D3G2':%45,D*-,*2B:)$GD*%5F
@r9909
CTGAGTNTGANCGATGCCATCAGCGAAGGGCCGATTGAAGGTCCGGTGGATGGCTTAAAAAGCGTGCTGCTGAAACAGTACGCCGGTGCTGGACACTGAGGGGAATACCAACATATCCGGTGT
+
&+!*#%))%&"'%$!$(*!$(&*(!''("*#&'(+&**!*(#%)+(&$+'$&(!()*!$&!*!$*)$#*(&')"$!!%'%!'#")$##&#(!("!*&&#$&)!""%&+$+**(!&+(!*++#'
@r9910
ATCGATGCACATTAATTGCTAGCGAAAATGCAAGAGCAAAGACG
+
*><D+'AAHC0),2B)!;6F=./;3+46A&C,.;.!"$5,3HD@
@r9911
AACCATAACCGCCATCGCTGGACTATCGAAGAGTGCAAGGCGATCAAGGCAGAGTACCAACAGAAACTCAAAGACCTGCGAAATAGCAGAAGTGANGCC
+
3$#26?+.,;'5,E:&?>H'=9:&<!A:F@-D.9=951!">3B:4;%49B+#$!'C%16=5')/$85<9H9;.+%<:,8)=?*-%$)'*8+)*;&&2GE
@r9912
ATTGGCATCAGAGCTGATGAACCGAAGCGGCTAAAGCCAAAGCCTGGAATCAGATATCTTGCTGAACTGTCAGACTTTGAGAAGGAAGATATCCTCGCATGNTGGAAGCAACAACCATTCGATTTGCAAATACCGGAACATCTCGGTAA
+
=$8./8'"@8.7%G;*;/16A36#%3%2>:59=+H:;6%5!*B4;7C4=.,>-H?'!3.GHF$7#3=<&<A5?-'3C@C&2+(FF52H&&7191"73-#*8?4'EBEA#$"),!<+%9@=&=,F1<H:2<8-C+,)</9(2;%)=&B/1
@r9913
NAACTAATGACTTTTCGCCAACGACATCTACTAATCTTNTGATAGTAAATAAAACAATTGCATGTCCAGAGCTCATTCGAAGCAGATATTTCTG
+
";8"5.A/%*E7>H1A25&69:!%E+A@>H:9@D@A@3C510=H0#5.40.':$A1*0?=*0):<=4D"D=G1D*+?G(2/4A:55!;5(B@,%
@r9914
CAACCAACAGCACGTCTGAAACGCTTGCTGCAACGCCAAAGGC
+
:G?!<2!7.C/+.H%%@3$?G%0H$<5:0<3$96EF%E'A'9?
@r9915
CCGAACTGCTCCGAGTCCACNTGCACGCCGACCAGTGCCGTGTTCGG
+
E@/7+5)G!D>E3'1?0+14;$(7HE->9?0*??H(>4H,"G*C1B*
@r9916
NCNATGCATNGCGATTTTGTTAAGCAACGCACTCTCGATTCGTAGAGCCTCGTTGCGTTTGTTTGCACGAACCATATGTAAGTATTTCCTT
+
"&%*+#%"%%(#)*)$"$)"**+*#*+)"#*'*+$$!#++'*&"#!*!$#+++'"+!'#*++&"&%"*&$"+%%%(*%"#$"%%!!()!'#
@r9917
TTNNNCNTCCATNGCCNTGNNNAGCGCCNATNGNGNNNTNGNGTNTCNNNAACNNNANANTNTNCNNGCNCAGTCNGNNANCGCNGCCNTNNGNCNTNAGNGNGANGCNANCNNCGNCNNANNACCTNNCNNCNACGNANGGNTNNCAGCNTGAGGCNNAGNNGNGNNNATNNNNNCGGCNNTTNGCATCNNNGANTCTCGTTN
+
##"""""#!####"#!##$#!!####$"!$###"##!!"!$!$"#!$$!$"#$!$!#$$""#""!!!""!$#"$$!""!!!$!#$$###$$#!""""#!#!#"$"$"$"$!#$"!!"$$"#!!!$#$$##"$$#!#!!"""#!$!"$###"$"!!$$!!$""!"#$!!!$"!""!!!#!!#!"""#$#$###$$#!#"!"$!$"
@r9918
NTNAGNGNTNTATGTTAAGAATACGCTCACNGATGCAAAACGATA
+
&"#&&(*"&%%)")!($%*%&##$#)"!%!!+#)%*%%%*&!#$*
@r9919
ACATGGGGATCATCCCGCCGAAGGAGTCCTTCACCTGCCCCCCCTGTTGCAGCAGGATCAGCCACGGACTTTGCCCGCCTGCAAGCTGCGTGGCCACGTCGGTGAACTGTGCAGGCAGCATACGCATAGCGGCTTTATACTGCCCGACGGAAATCCCCGCTTTCTGTGCAGCCAGCGCCTGTCGGCTCAGCGACTGTTCAACGACTGCCGCTGTTTTTTTCGCATCACTTTCCGTACCAGAAAAATGACGCCTGACTCTGGCCATCTGCTCGTCAAATCTGGCCGCATCCAGACTCAAATCAACGACCAGATCGCCTACCGGTTCAGCCAT
+
C0EED:@2H!3HB6F0#3$1)?)D"?%*9E27E'C?!C7/0B:,"F$(/D0AA5#-F8?A"-:?/3FD<85'8)03&B5B,5(.F$4?)&E,C8*H!<E&(.;?.+79C=9(!C1)H5.B#%!BF>7D$79$B9(4D08>B:A7D1*C>&',FH:F,2$4&(0"$(<,&-$!$8!G//;A1#7+"G$"@?);53>%$H8GF=(D:=)'>C8F2E47.2F/2%+**4):/64B4;"FD$>6B/;,?E.EB8(B2!07DD@=*'!7&=G</7)H3/-'D.!.3?(H$C7C+(5F)52*$3H"ED.3.3FG-.B,*D'"*B7*41/)#H?>0"D
@r9920
GCATGCATACCTTTNCGCCATAACTGTAGTGAATGTCTGTTATGAGCGAGGAGCGGAAGTTAACACTTATGAAAAATGGC
+
B+?6"7C0651.D@'(1!:?*,,B*H=&$'<7&!<F!5B86@4>>3)DE$14H=?A%<#9-E9??=(%B5"H:#<3<*0+
@r9921
TCATANACTTGCNCCTTTCAGTCCGAACTTAGCNTTGATTTCTGCGATCTTCGCCAGAGC
+
.'2:.-%<-13>*-12#H9,#$0+F45+:9,H@>%""?)BA(/,7>5(942)71/8?=&7
@r9922
CGTCATGTCCGCCACATCCGGGGAAGCGGGGATAACTTCATTCCCGTCCGGGCCAAAGCGGACACCTCCGGCA
+
:'./6#5<4:="3A51E0%EF'7*FD'-18)2%1$1%(A+&)+<:C>%5G*.G6E;3*C/D="@='!'(7&-2
@r9923
CGTTAACTTCCGATAAGCGTCGTAATTTTCTATCTTTCATCATATTCTAGATCCCTCTGAAAAAATCTTCCGAGT
+
F,5$@&FG;)1A8,A$"1%)!H%&/?:>!'@.?1$%6:-;+!.5>5G#3(>5@1&,/-2&5<<9&9#122&'$,)
@r9924
ANAAACTGTAGGGGTTGTAATAGTTNATCCGATTTCTCGCTGTAGGGGTACACGAGAAC
+
!")<9>8.(DA$$++*E?>5;G(F;5.4)GF/F9+6D%A19A;G?'31<%3D:>22A++
@r9925
GCATATTGCCAGCATGGCCTTTAATGAGCCGCTGATGCTTGAACCCGCCT
+
HB+E#!.:A>2.31C>>!9$)%H005+3#=G1H<A33>C%!G.6!)03-D
@r9926
ATGTACCGGGCGATGTTATTGAAATCTGNGATGATGACTATGCCGGTATCAGCACCGGTGGTCGTGTGCTGGCGGTGAACAGCCAGACCCGGACGCTGACCCTCGACCGTGAAATCACGCTGCCATCCTCCGGTACCGCGCTGATAAGCCTGGTTGACGGAAGTGGCAANCCGGTCAGCGTGGAGGTTCAGTCCGTTACCG
+
D,=,"A&..G48?'E<B>8$:(7GG6H>30!73,CC!5@A:E13F('F!,=@:</F4F>#>7#,,*:<!@F962D2G'<0#@49,&,?)F>@F).#94$!0E&::(%1)+#F?CD)0<F'',G!1<<GE-%/0%)??E=G<E28!18G&%(B22.D7#8<2B+AG!E,71,&C=!H!?05+7B/;@CGB+&4&!%-(;>!:
@r9927
GCAGAATTGGACATGGATACCCCGTGAGTNACCCGGCGGGCGCGCCTCGTTCATTCACGTTTTTGAACCCGTGGAGGACGGGA
+
@/0"@*((;E.0?H<7085E?+E.38A;H=45;<<9<2@:"&9<6,5H5/'D""<=>538$2*D(&*42(F?'=8:#2/2'5&
@r9928
CGGGATGCGTGTAGGCGAAGTTGCGGAGCTATTAGAGCTT
+
57$136:91(-F;@.7H0%;&<4$#)F@=E1)&-"!/%?!
@r9929
GATCCCGTTTTGTGAGTTGCTGATTCGTTCGCGGTTCCAGATTACCTGCTGATGATCAACTGGCTTTCCAAACTCGTATTCGTCAAANGGATAATCGGCGTGGCAGATAACATATTTTTTATCTTTGCTCACCAGTTCGATGATTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGAATTTCTTTGTCGNAANCGAGATTAAAGAACCAGCCACCGCCNTTAAGCAGCCAGTGATTAACGTTTCCACGCTCTGATAAGCAATCAATCATCATTTGCTCATGGTTTCTACGTACAGCTCTGAACCAGGGGAATGTGATTAATTCCAGGCATTCAACGTTC
+
-8;'H808B&&2,G%3%03@%"D".B9$3B85$,H<+<E@38;+<8D4-@B1AB7#B/:*;$7'-E1@1'3;.G@:F%=/$(%5:"!(6F:80:B(-$/(21,(:4G*7GE%D2F..H$"5#AC4"(=9%+%A'8G,%)D#5331@H#3<5HA">91H?,4H!'B?'?<,6G+$!@67>=D<409,6?91<&:'HD>7G/=:1='4@(:2)2"&#H5>,6++A&E$C+H?8;%7:/1FD#&"=HF<*E85)".E%',.!/+8ECA<:!3-*E?(,%??A$B8--'+'.D>:);=3%H*A+'#*7?6-A+7F+*83"F;)8,&3D;H#%!*-;F.";HCD-F2
@r9930
CTGGCAGCCTCCGGCCAGAGCACATCCTCAAAACGGAACGTGCCGGNNTTGT
+
)#4,-'*5CE4;E$D&#4,EH?$"9=#3;G5C@A+*14C,(?%"7<=-5.+E
@r9931
TATCAATGCAGCATTTGAGCAAGNGCGATAAATCTTTAAGTCTTCTTTCCCAGGGTTTTTTAGTCATAAAACTCTCCATTTTGANAGGTTGCATGCTAGATGCTGATATATTTTAGAGGTGATAAAATTAACNGATTAACTGTCAATGTAATACAANTTGTTTGATCTTTGCAATGATTCTTATCAG
+
1>;93:-*'?/#,@=8EF;/!<G0(7E3!@+;,=:>D,/>>*0,;8>#!?(-.?-4?C,48,6"7C>9.<0.#0>!&$#4CG12G4D(G&E-G7(>2G&H8;?-(66#><?;@(<D0&!4A"=@H,.)#71%:&GDG&)!9E63%71(;:D%!6EE$47G"-:6;8H0,***<D!#)%CF5G$20C-
@r9932
GGCGGGTCTGGTCATCAAACCCTTTCGTTGCGGCCTCGTTCGCCGCCTGCAATGCCCCGGCTTCATNGCC
+
:-/$B683F/E%D&G<B801%*'G!$5+1)H.D,2G0;A390(H2;38C9/0F&GG811C-G(1:79@E5
@r9933
NNTATANGNNGANGNTACNNGNGTGCNNNNNTNGANNTTTNTNNNCCCGNGGNNANACATNNNANTTCNNGTANNNNTNCCNNANTGNNTCNGGTNNCNATTCTNNNNGNNCNNCNGNNNCCANNGGGNGTATNTACNAGGTGGTAGNGTANGGTNTGNNNNNTNTNANANNTNNCNNCAGANATNNCNGNTCNNNGNNGNCGCANTTNAAGNNANNGNNNCTNNNNGCNNNANCNNNCAGCCCNNANNACCNCNNNNCNA
+
$"$$$$!#!!$#!$#!!!!"#!"$#$$"#$$"!$$"$""$!!!"#$##$!#$#$##!"!!!##$$##"!"#$"##$"#"!#!!!!$!"$$!!!#!"!"#"$"$!!"##$!!$""!###"#$$"$$!#"$!$"$#"!""!"$$#!"$$###$#"$"!$$$"#!!!#"!!!#!!!"$!#!!#"!#"$!#""$!$!#!#!#"$!$"##""#!$#"!$!$!"$!#"$!!!"!$$"!""$#$!$$!$"##"!"#!!!!$#$#"#!"
@r9934
CTTTCCAGTTTAGCAATACGCTTACTCCCATCCGGGATAACACCTTCGT
+
.//*:;%!=&-&*?2:<!3"9;@*#=D=A=F=DAD*2-</&>,02G<2/
@r9935
AGGAATAGTCATTCCAACCATCTGCTCGTAGGNATGCCTTA
+
0G36CA+1@;D.5/28'&&A972>/A#<#329@5F):'#06
@r9936
GGGTTAATTCGCTNGTTGTNGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACGTATCGTCTGGAACTCCANCCATCGCAGGCAGAGAGGTCTGCAANATGCAATCCNGAAACAGTTCGCAGGTAATAGTTNGAGCCTGCATAACGGTTTCGGGATTTTTTATATCTGCACAACAGGTAAGAGCATTGAGTCGA
+
+(+&&&"('%#*$'"+)!$"%$(!!)*!!)""!"(#+('&%"&))%&&"$"+#'))#')"!&$#*$!&!#+)!%%'$!!)#""$**'$*'")$#)#(&)*"+%)&"$("&*%++#(*%($&#)%%#""%!*")"$*)##!*#&&#&"*!!*)""+%"')+#$''*"$&'!%')'$$('(#'"('(%!)$##(+'"%%'#%$+&))!"&&!'#$***%*
@r9937
CCGTGCAGGTTGTGCTGGATACCGAGGCTGCAGTGTACAGCGGTCAGGAGGCCATGGATGCCGGACTNGCTGATGAACTTGTTAACANCACCGATGCGATCACCGTCATTCGTGATGCACTGGATGCACG
+
A,C0B?B%5<2"(2&8+89%4;GD.BCC/:@7?'&,C9=H'!55E(&0F9&D"F4@BF'G)-/-E=79<?0H3+%B:A>#*+;2+A&+.A+F>*/<*.@:G/B5()CC=67A*,@,0.//3#!G2FH=+"
@r9938
CAGTTGTTTTTGCATAGTGATCAGCCTCTCTCTGAGGGTGAAATAATCGCACGCCGTTCAGCGGTGTCTGCCGTC
+
AA4!F("D'H7(<A8C'#E#0-'&7A4<1!69>#D5%B=""8-?@:-(03E6=4#FF%0//%@?(?2:HH()D0+
@r9939
AAGCAGCATATTTGATAGTCTGGCGTAACCATCATCGAGATCTGCCACATTACGCTCCTGTTCGGCAAAGTTACCTCTGCCGAAGTTGAGTATTTTTGCTGTATTTGTCATAATGACTCCTGTTGATAGATCCAGTAATGACCTCAGAACTCCATC
+
++&:9(1B&:C,)+<E#,G,*1H!4="5F86;"DF*1.AD*>>@#.,E#:E?A:*?/>F132#3;.0E,6,)B0?$4<@8/)+8(5?-:G@?31B#C!7=78*.352!=?8;$,3:H<;H2%H+E5F";,*9G#(A!+(:-B/38(9E-,5':F..
@r9940
TACCAGACAACCGTTACACCACGTTTTCAGCATGAGAAATTGCNTCCGTGGGCCAGGTGGTAAGCACTTCCTGCTCAATCTGTTTAACGGCTTCATTCATGGACGGCATCTGCGTCTTCTGCGGATGGTTATGCCACAGGGAC
+
$D&>&9H&8G#;1#-*;"(&F=/!=1-+.??%(%1C;)<)+!%F-,#=3AG+/0'CB0(7>A7EH&4)-C+F%88B/@&3F6')%8&&"BGB.5.E>*D.26:C8=+5;"-F;?")=@?<E<H/"#@5H*?B&1:F0G32+<$
@r9941
ACACGCCGATCACCCGCACCATTACGTCTGCAAACATCGACCGTCTGCGCTTTACCTTCGGT
+
4$"%0C/!.9#C@7B#6-1H2?B&3)&.@=)1<CC4;",A-7"!C@(8/%(@<F4$A5?E$$
@r9942
GAAATTTCAACTCATTGTTTAGGGTTTGTTTAATTTTCTACACATACGATTCTG
+
C-A&'@9B4F09D?#A:=$D8/725'<-HF73.5-8@;C(H-/8/4-?:5"#G8
@r9943
GATNGNANNNTTCAATNACATCGCCCGGTACATGGCGAAGCCCTTCTGCGCCGACNCTGAAATCCACGGTCTGCGTTTCCAGCAGTTCTGTT
+
#))$'$%%#%(+(+')+*)!)&#!%*&%+%%#"++$%+#+**'+(%())#%*"*")&$&*!+)%(($(!%)%*'("%"#)$&&"$+&'!$('
@r9944
TCAGNGGTCAGTTCGCCGGGCGTCAGGTCTTTAACTTTTGCCAGACGCGACCAGTCAACGTCTGA
+
,.5CF923<;)<"5GA''2+/HH&>=6G674E.G!FB8:H><9*27008",9<(H3D=$5%6D'/
@r9945
GTCGTGCGAGGAAAACAAGGTGATTGACCAAAATCGAAGTTACGAACAAGAAAGCGTCGAGAGAGCTTTAACGTGCGCTAACTGCGGTCAGAA
+
?+30G!D>#-6,H*32$>5!:9)!$DG"!$$0&GF%H!(381/:'H('C.7""!@<A46)AC=E6E&5)9.<CA69)BA.1#E9.(/C>&#4=
@r9946
GCACTTTTGCTCTGCGATGCTGATACCGCACTTCCCGCAGCCTCTGT
+
1+*&2!D)F;<;#2F:E0#!@(*/4:-?;!C)10?*5C+C+5+>2=;
@r9947
AAAATGCGCANCAGCAGAGCGATACCGAAGCGTCACGGCTGAAATATACCGAAGAGGCGCAGAAGGCTTACGAACGGCTGCAGACGCCGCTGGAGAGATANACCGCCCGTCAGGAAGAACTGAACAAGGCACTG
+
0DA,+#HHA87%')-6!$63-<B48*',40%6$1*B(B'84$=F(*!3-3G"#:%??F??,?1($<<>)0H-8%&H."54+.A3"0H<BB).$B)H,34;'%C0B??F9"+86G(4&&F@G09;$":7#8&=6#
@r9948
TACGCCAGCAGTGAAACCACTCAAGTTTGCCAACCAAATGTATATCGATACCGGCGCAGTGTTCTGCGGANACCTAACATTGATTCAGNTACAGGGAGAAGGCGCATGAG
+
F!G18G26($;%C52-:E3,B=?5E8C*)'.G24?D$&"-?1D-!/'@!&D(!@G8F'/3(98%072.D<=-D"2->F-+9B&(CEG?,CH=-#>*4<!F/6,$)'*84+
@r9949
CGAGCAGATGGTTGGAATGACTATTCCTTTNTTACAATGTTTTATCTTACTGTCTTTGATGAGCATGGTGAAA
+
@474?.*>,+//.)+.F(08/+='B#/>'2C%G3?,"=+4A>5:(.4=!!55>E(<F;42,"!(DG8F#)=;+
@r9950
TCAACACCCGCACTATCGGAAGTTCACCAGCCAGCCGCAGCACGTTCC
+
/&7!!H.F0B@FGCA+C!C0&8EC@H)$*)0477HE0(";>@7@8$+(
@r9951
CAGCTTGATTTCGACTTCGGGAGGGAAGCTGCATGATGCGATGTTA
+
G*@''!;'*/9-"%EC:&2A!7+=.$-=/'!A(!"8E@DCF&C-:<
@r9952
GTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAATAA
+
/B89!)/()&@H46:$/E=#;'>D1!B%=EH5$5>970:..<A(328!24#0B30(21;AH:%'9
@r9953
TTATTTTTTGTGTAATGAGCAGAACGAAAAAGGTGAGCCGGTCACCTGGCAGGGGCGA
+
D%=9.G!(42(>$!&B<E3!3>*:H2'7F810D:D!E;!%7F1)>AA/D$*D!H23C:
@r9954
NATAGTACGTGGAAAACGGCGTCAAAAAGAACTTCCTACCGGACAACACGATGGTGCTGGGGAACACTCAGGCACGCGGTCTGCGCACCTATGGCTGCATTCA
+
"&!('D+B0??5$G72DA%>;B."9.$<!@%&*-((B:$')A?-H7>2-C3!/EA$!$#$D3?CC*0$#*5B+?07$&45(EC='B:-C1HD7?;-55.'.7G
@r9955
ANATCGCATTTTTCACCATGCTCATCAAAGACAGTAAGATAAAACATTGTAACAAAGGAATAGTCATTCCAACC
+
(!+#)$("*"$''$***'*###!)+$$**$%+'"$$)($%$&+&)'((##'+&#*"+!$!#&!+'#'!$"()*$
@r9956
CAAGAATGCCAACGGCAGCACCGTCGGTGGTGCCATCCCACGCAACCAGCTTACGGCTGGAGGTGTCCAGCATCAGCGGGGTCATTGCAGGCGCTTTCGCACTCAATCCGCCGGGCGCGGTT
+
C(D;%<&&0$H08,<7G6C0+!<:9#8<'3+AC3H-A&AF#FH3B&@.;@.-"#;!/?<9@;.5$"#DE!!.1G<*E9(57,*#9A:/,+&/)(#<:"1="?7CF5;(E;$>;5"51CF>8=
@r9957
CCGACTCTTCACGATTATGGACTCAATGCTCTTACCTGTTGTGCAGATATAAAAAATCCCGAAAC
+
;G%H5&'H@2B8%7%;87F1/-E1="#C3B?&A1.'C>2%9:!4:8CF3<-/?8G$,F+2?BF5(
@r9958
ACATGCCAGCGGGTCGGGGAAACGTGATCCTGACCCTGTTCACGCTT
+
=)6/>>0G<8.70"'8B#?3FD=D.9@(75B8A5&6*/F$B;=/H;<
@r9959
AANCCCGAAACAGTTCGCAGGTAATAGTTAGAGCCTGCATAACGGTTTCGGGATTTTTT
+
:7B'>"A;=($7*3>5-90#<!);*.D-&)&:10:,9.43C<<'"G$;D!B(29+0EC.
@r9960
ACAACATCCTGCTGCTTTAATGCTGCGGTAAACACACACTTCCAGCTTTCTGCATCCAGNCAGCGACCATGCCATTCAACCTGACGAGAGACGTCACCTAAGCAGGCCCATAGCTTCCTGTTTTGATCTAAGCTGCGGTTGCGTTCCTGAATGGTTACTATGATTGGTTTGGTTGGGTCTGGAAGGATTTGCTGTACTGCGTGAATAGCGTTTTGCTGATGTGCTGGAGATCGAAT
+
@=A$5'(7,-'1BE:34@11'=<@F1=:&"A.//:<$%:0+;D1256H%72(?.$%@A5H9D1-"6=/A%@H)+:7<>!(+G?4.)!2!#7D5.+EDE9GE%0#-@41C!E>..AFAG4*$&6BG+:7&3B'=(%3%C9&+++'!>#/8#(.)H!,89,163*-6HB//HA)@+?>,B?7#991#9:FG/D2F(,7>4DF(6+@@?.:D>)24:275>B"$7<(F*1A?36$*8*9
@r9961
TGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTNGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAACCTCCCGG
+
(3);D)%#$4=0@770H-"E7(9GB6D81.DD%#435?",EA47,/.BB6?2'3<=>)BD4<FH"?4#7$):)73$1+1?@.<0B-/7B,AE&9/.(E0C3D
@r9962
CTCAACGTCAATGCAGCAGCAGTCATCCTCGGCAAACTCTTTCCATGCCGCTTCAACCTCGCGGGAAAAG
+
>3D(3%)"6@7;9*8"3C/6C1E8!%C*;&F"9-9>/$B2.9D@..'<%$FF</1>/41G>=@-?!5D,G
@r9963
GTCTGACTCCGCCTGTTCTGCCTGCCGTTTCATCAGGGCGAGATGCTCAATGCGCTGCAGGGCTGACAGTTCAGAAAGCGTGACGGTCACACCG
+
G(%9/0;@1D1%$#1#/)>7HC9(76)8@-)D9D9.1,4168)D43B;8EH'%8?HG(&)7#($<>6/E",59+4?E>,8=",./+>4@.$!E,
@r9964
NNCGTTTTTTATGNAAAATCTAATTTAATATATTGATATTTNTATC
+
#+!&+"&%$)"#&)$+%"!!%'$#'*&)*!*&+#&)+(&$#"#)!)
@r9965
CGNTGANTAATCATCTGCTTTATGGGCAAGAGCTTTAGCCAGA
+
E'#1/:7D.>'8B4&@(9;&">%1>,.A"7C;"EF;2.!"6'+
@r9966
CAGATANAAAATCGCCCTCACACTGGAGGGCAAAGAAGATTTCCAATAATCAGAACAAGTCGGCTCCTGTTTAGTTACGAGCGACATTGCTCCGTGTATTCACTCGTTGGAATGAATACACAGTGCAGTGTTTATTCTGTTATTTATACATTGTAAGCCGCCAAAAAT
+
**9H0B4@&@=0(E.#A)B0+)?5,3'+/C"<8=181)2;2.)5&1.;2%.E5',)7-74%:(8-"-:8D<+=@'9$$:GB"$!!G1E@%*9E<91B4H>+=#/%;-C/'?3$:A<=7=-'3?#C*#%6,#"<BE<&E667,6.=8.F,"#$E31,/4//32(>13(9
@r9967
GTGGCTCCGGCCTGAAGAGTGAGCGAAGCCCGGCTCGGACAAAATGCCGCAGCCTGTTAACCTGACTGTTCGATATATTCACTCAGCAACCCCGGTATCAGTTCATCCAGCGCGGCTTTGTTCATGGCTTTGATGATATCCCGTTTCAGGAAATCAACATGTCGGTTTTCCAGTTCCGGAAAACGCCGCTGCACCGACAGGGGGAGCCCGTCGAGAATACTGGCAATTTCACCTGCGATCCGCGACAGCACGAAAGTACAGAATGCGGTTTCCACCACTTCAGCGGAGTCTCTGGCATTCTTCAGTTCCTGTGCGTCGGCCTGCGCACGCGTAAGTCGATGGCGTTCGTACTCAATAGTTCCTGGCTGGAGATCTGCCTCGCTGGCCTGCCGCAGTTCTTCAAC
+
.</1A?>7?+A9F'<;/CGG$%%3GAD2;B3B9:B8%2+7D.%&&#2%&G>@325(HA$157=C65@=?@(G+5@@C;#2(=7+6HC&GG1,&CA+?#!F-6%<5<>$4/90-6>=':9,$/B!DD9A@7@A)5B%5D.@.)B52DH1608C>&B7&F8,B+BG!6DAE+<3*#-0#+.E'@079@6=7<)>D8?@-=BB(86;>3,0++%3"/;;A.9,;1*(D>,-."6/B=6,!G9'A4G+634?GC>F)F9;D+-*):G#;8B*D)3;C,::0%>4*9;=>9";/F=+A."<4/G1'/)CC5*,/,;379"@$A*D>:C.1@,.FB/%(1HGBHC+&'1<-A;(!4!4A5D3@G)%7&F.C<4/G%CE=@=D;;79<5B23%=(*$50"@0!>0."<'9F
@r9968
TGTNCCCCTACAGCGAGAAATCGGATAAANTATTACAACCCCTACAGTTTGATGAGTATA
+
#0+B#/BG%!?>BHD2/H*,(F6;>5%!66&8;)#"@B-,:...02G87""?2)<!)>+8
@r9969
CTTAAAGATTTATCGCACTTGCTCAAATGCTGCATTGATACATATTTTGACCNTGAATTATTTCGCTTGAATTTGAATCAATTCCTCCAAACCGCAAGAACAGTAACATTTATTATTCAAAA
+
7##3<'EG"*63$E/E:(?&8B.FA"='!"'%4>/$"G26F;#"(HE%A*3%<A#!(H(1H<*C:43@%").5,(9=48BG.%#(EGHF$H4+9CG!!9A&1C(9-.)A<H82>&'F+5=E>
@r9970
GNNCCACGGCACCTGCAGAATACGCCCGCGCAGATGATAATTCCGGCTCACCTGCTGGCTGCCGAACTGCTCC
+
&%%"%)$&(#(+%(!%"#&*$"$)"#+#)%*&"!"!$$'")&%+"$""$("#&'')!#&'+!$&)'+%$%#!(
@r9971
ATCGCCGGCTGATTTCTTCGCGTCTGCCGTCCTCTGTGCCACCACGGACGCGTTACGCGCCA
+
B55#C+4$B/G!-8H&0$&F(579#<9-962+4103%2@DF-0,)$));F*<"9;3?;:!A5
@r9972
NCGCNNATCGTTTCATCGGCGCGGGCAATGGCAGCATCGAACAGGTTATCCGAGGGCAAGTGAAATCAGCCACAGCGCCTCCCGTTATTG
+
&%''$!48B9*+%4(;$;#E#-:0.00G(=9.0621A926&+1C+,<E?@"1FC3<0)$8$3C("+4?(0;C9%/BB7=6@$043$>.=2
@r9973
NNTCAATTTCAGCATCCCTTTCGGCATANCATTTTATGACGGCTGCAGAGTCATNAAGCACCTCATTACCCTTGCCACCGCCTCGCAGAACNGGCATTCCCTGTT
+
$+$#")+%"''###$*+"$!($#%"%"%&!*!!+!#$(&(+$!')%%"%!'+("))**()#*&#))$*!+**%'*$&*+"!*+&$&)&&+*$"!#)%'+!#()#'
@r9974
TTTCTCTGGCATTTTTGTCGCGCTGGGCTTTGTAGGTAATGGCGTTNTCACGGTAATGATNAACAGCCCATGACAGGCAGACGATGATGCAGATNACCAGAGCGGAGATAATCGCGGTGACTCTGCTCATACATCAATCTCTCTGACCGTTCCGCCCGCTTCTTTGAATTTTGCAATCAGGCTGTCAGCCTTATGCTCGAACTGACCATAACCAGCGCCCGGCAGTGAAGCCCAGATATTGCTGCAACGGTCGATTGCCTGN
+
$+)+#*!%(*((''#*$&+#!&!)$+'*('"")&*!#(#%("*+*%#$'#"$(!''%!&$%%!!+*$""&+(#&$&!&+)**"*#'%!))''##")+"$#'%!%%"))#'#**)#%'#!($*&%)(#)"*))*&+&)+%&(")*%"("'#+#$!')*"%&"%*))%!$&$'*&*!('&''))%+!"*'(+#*(%!*%'+)#*(&"+#("#()*#')%#"&%(()+)*(&"+&+'#*#)"*%!%#)*+&(!%#)%&'#&$'!+
@r9975
ATATGGTTTACGAGTATTNCCGGCGAGGCCTGTATCCGGATGCGGAGTCTTATCCGTGGAAATCAAACGCGCACTACTGGCTGGTTACCNACCTGTATCAGAACATGCGGGCCAATGCGCTTACTGATGCGGAATTACGCCGTAAGGCCGCAGATGAGCTTGTCCATATGACTGCGNGAATTAACCGTGGTGAGGCGATCCCTGAACCAGTAAAACAACTT
+
=;5A><;EE*>1!?(H"33GBD6(CF4EH60F..05)+$918<%+3=,A5FCD+,F"#H;;!C@/7B'4"7DE6*;$(+497('&7)?+,2:=D,#=.F0'#"6$.9,8$C'2C42C=C,$1G%4+%"#4>CB2,9/>+-E'CE-%)8DG":H)&*F@#.&9EH<G/8H"F0"D+F+1<FBE?+G*%C?5@;;6$?"*D74(*8;931,!06*@*&$(1:*
@r9976
CAGTAATCGACCTTATTCCTAATTAAATAGAGCAAATCCCCTTATTGGGGGTAAGACATGAAGATGCCAGAAAAACATGACCTGTTGGCCGCCATTCTCGCGGCAAAGGAACNAGGCATCGGGGCAATCCTTGCGTTTGCAATGGCGTACCTTCGCGGCAGATATAATGGCGGTGCGTTTACAAAAACAGTAATCGACCCTACGATGTGCGCCATTATCGCCTGGTTCATTCGTGCCCTTCTCGACTTCGCCGGACTAAGTAGCAATCTCGCTTATATAACGAGCGTGTTTATCGG
+
<+)2D&G@E85D1F!&</34;'5D)G0@EB.H;$>H)0B%F<#94'#C35)+'D#%30BHE+$-"A29!6HHG3&+*&B-4-&4H!$%#*H;4+6B(*/D)?D02HE+5-84B1%@8$F63>#,>B/C4@E$9/37/,@*H".=(4B8#-;-*:F.:*F*@94=3.45>)2*B7#E=),2=>,$@)D88:57,(8HF$$."F3%@#:D5A&CG,230//B='@33("G<G-34=-5,::>>&.D1'+/(*H,.4-)9B<<6;!31/9'B1CE!7=?5,E:9>>>'.B6'2*=(D4-
@r9977
CCCAGCCCGGCAGCGATATACCGCAGCAGTGACTGCTCAAACACGGAGTAGCCGTTATCCGTATCCTGAGCCGTCTGCAGGTTCAGTGAGTCACCCGGCATCAGGTGCGGTACTTTTGCGCCTCCCAGCCGGACCGGCGCTGCGGCGTAATACGCGGCAATTTCACC
+
C@=0"(G*4=&;887/H#C,4#.:CA&=B;BC-;/>F<9'B7*:26?65-;172=05#EH*:9)A4H7E>'H-8(?.08?92<G*H@%/+/581=6-#</!87A@==)G>:"@.6DF;(<F-?"08C15!.'#6E0)->B2#)9*0*=9-&'3&--'(D+-G#%<CD
@r9978
GANCCTGGTTTTTAAGGAGTGTCGCCAGAGTGCCGCGATGAACCGGGT
+
%*!+%($(+&(!)(%#*)('+*&!!%(!'%'!*%!+$!+&**+%&)"#
@r9979
NCTATNAAATGAAAAGTGGAAATCTGACAATTCTGGCAAACNATTTAACACACGTGCGAACTGTCCATGAATTTCTGAAAGAGTTACCCCTCTAACT
+
';09$-.7AC#G48ED-H!A03)37D:07=>1%2B"C91&;&(#)?06A3>G/D6(()>"6&5C<>+G*)D%H4?/?FGG>*3!8-HD7FC8G(&6!
@r9980
CCNCNTCATCACCCCTGTGCCNGATACAAAACCGGTATGGGCGCTTGCCAACGACATGAACTGCAGTGCAGGTCAGTTGCTTGCCA
+
%!!))'$)(((*"%#&#&)(#"*%!)!+%#%)))#+%(&""(&*$%+&)$!'#&#(&+)()!&++#&)((*&"*$!&%&%(**'$$
@r9981
CATTCAGGCCGCTGCGGCGAAATTCCATTTTGCAACCGGAGGATTTACGGGAACCGGCGGCAAATATGAGCCAGCGGGGNTTGTTCACCGTGGTGAGTTNGTCTTCACGAAGGAGGCAACCAGNCGGATTGGCGTGGGGAATCTTTACCGGCTGATGCGCGGCTATGCCNCCGGCGGTTATGNCGGTACACCGGGCAGCATGGCAGACAGCCGGTCGCAGGCGTCCGGGACGTTTGAGCAGAATAACCATGTGGTGATTANCAACGACG
+
+>G@8C):47&2EH572)G,:.68/1H-/&='B48+%$@<3;&')59D0G=$=%$C>(>&)71#*4;%!3,8,:FH,(@%=%>3-91<0!&FFG@/1)>58"HA7=<0,HE;2C5917#B*@1&A?@H>8/(&/+/7<)@;E60*>2C$F,%@*%%.%?14:?(6.<$',+"<#@:/?23)HE3%3=<A?1:/9#5+;#>8#&F00C)A641B+5B*6>D*"C"8%85H3:@%=C81F421D..2%$2128BA,6C@%>)%:6);"5@2
@r9982
GTAATGGGTAAAGGTTTCTTTGCTCGTCATAAACATCCCTTACACTGGTGTGTTCAGCAAATCGTTAACGGCATCAGATGCCGGGTTACCTGCAGCCAGCGGTGCCGGTGCCCCCTGCATCAGACGATCCAGCGCAGTGTCACTGCGCGCCTGTGCACTCTGTGG
+
87*6@0D+A6'$(/3;)'%,''"9(<<C7FH$=@$567C&5B47A*;H4%@%)<,=9HGE9>@HE<30C;GA2."1&"1%D@.-%30:FE4-E-'8A&4;,,B/(!7022,4A012-@'<(F-$0@EG@)@:6"2H2*1/#F$::E->?#:/3=F#"G*@A)4A8
@r9983
CGCCTNTNGAANNNTCAACAGCAGNCTCAAAACATGACGAAACACTATATNTCATGCGTTCAGTCTTA
+
()#'%!'("**"%+('*%&!*(!+'!)(&(!"+$+&+!$$%'%%(%(!+%)&&*$')'"!')&!$!#!
@r9984
TTGAATAAAACTGGGTAAATTTGACTCAACGATGGGTTAATTCGCTCGTTGTGGTAGTGAGATGAAAAGAGGCGGCGCTTACTACCGATTCCGCAGTTGGTCACTTCGACN
+
<:A=),"7G+=":<+5#F7)E6*":$>17@D$#07=)ECH@4?+E42B,'6$';GH>%1&&0?(=./9?E15.$14#1'34%.+;<F/-H<6F#('(5!5(#7H><#-35B
@r9985
GCGGCATACCTCAGTGGCGTGGAGTGCAGGTATACAGATTAATCCGGCAGCGTCCGTCGTTGTTGATATTGCTTATGAAGGCTCCGGCAGTGGCGACTGGCGTACTGACGGATTCATCGTTGGGGTCGGTTATAAATTCTGA
+
4%%*:5GG&&;4//H:F81F,3*H&3(;HAE16%@?"'-D'/?91$F>,13H06*(!,#B#$6G237*H:;9/;D44(22F38,C1D"?&7;/4&7$.,D&F%)=-C599D,@5D'7&4=0$C04"?9D6;#??A#E>F4?C
@r9986
CGATGTGCGCCAGCGGAGTCGTGCGGCTTCGTGGTAAGCACGCCGGAGGGG
+
)'0B2*@,(;!4"C5H2A(<31?66A$13>(/&/3$+&)>D.FH./,A7<B
@r9987
NCTGGCAGGGCTTTCCACGGCGAAAAATAAATTACCGTATTTTGCGGAAAATGATGCCGCCAGCCTGACTGAACTGACTCAGGTTGGCAGGGATATTCTGGCAAAAAATTCCGTTGAAGATGTTCTTGAATACCTTGGGGCCGGTGAGAATTCGGCCTTTACGGCAGGTGCGCCGATCCCGTGGCGATTAGATATCGTTCCGTCTGGCTACGTCCTGATGCAGGGGCA
+
!++&"'!"*&#*&)+&%!'%&!')'+(&%%)"$)&($(+"%+($)$&$(%$'&'&'&"!$&#'''%#$&)$""+%"))#'#)*)*+)$"+()("))&")'*)+#"#'+!#)+"("'*(')!"%$$(&#$$%+%*)&'&&*"+"#+'*#)!)"$(*+"!()***'%*&+#!%'()%*!!%+'!&"%'#%#)+"+*#*)'%#+'*)%%+()&#+'%$())'&%'!%($(!
@r9988
CCNATTTCTCGCTGTAGGGGTACACGAGAACCACCGAGCCTGATGTGGTTAAAAGACAGGCACAATCTTTACTACCGCAATCCACTATTTAAGGTGATATATGGAAGAAGAATTTGAAGAGTTCGAAGAGCATCCTCAGGATGTGATGGAACAATACCAGGACTATCCGTATGACTACGACTATTAA
+
)*'+)*%+("+$$$"!#("!*%*)'!*)!*)&%&*"(!#+&*&)%!"$*""#$#($'!))"$!%%)(#*%$(%&*(+'$"'!&)%&&+)#(*)$#&!()!"&'$+&**#++$%('&*'##%(&$)!*(#*"+#%'"'()($*#+%#&#('*"++(%)!##'&+!!$&!$+$*(*$""#))#!")&("
@r9989
ATNNNNNNTGNNTCTGNGCNGNTTNNNNGNNANNTNGCTATNNGNTAT
+
!$!"!$""$#"!!#$#!!!!"!"#""!#!"$###$!"!"$$""$#"$#
@r9990
NCGAANAAACATGGGCTGTTCCGGGTGATCCCCATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGTCAGCATGCCACGTAAGCGAAACAAA
+
#+)()#&&"!))&'$##*!*#('($"$#$"&+$)*%"*)#*(#**%+)$'"'$#'$#++%')"#(&#$(%)$$"+(#"&')"%&*!"*&$!"'
@r9991
GACGGCTGGTATCAGGTACGGATTGCCGGGCGGGACGTCAGCACGTCCGGGTTAACGGCGCAGTTACATGAGANTCTG
+
/C((:9/8*8#38+3H8"$46H/E0=0+'-7&@,!:D?+27649E9'!9$4>+G)D<,H**;#2>AB=)-?02/./$G
@r9992
AGCACGTCAGAAACTGCCTGCATCTCTTCGACCTGAGCAATGNCCAGCTCTTCGTCACGCATGTTCTGCATGATGATGCGACGGCGGCGGTAAGCCGTGTCCGCCAGATTCTGCGGANCTTCATCCGGCAGGCGACGCAGGGTCATCTGCGGATTCACTTCATGCTTNGGCTTGACATATCCCGGCGTAAATTCAGAGGTGGAGCCGCCACGGGAACGGATAACCTNACCGGAAACAATCGGCGAAACGTACAGCGCCATGTTTACCAGTCCCGGAATTTGTGAGAGATAGACTT
+
9%H0DHF+2('*>2$BE)0(D,?:&75"(E<9E-H*!1>$0@08)>BG*:C*AA27@DBE-!8"<EGG2#:B79#)05D*3-0@H2B>"0?86-G2@:,65!"H4(>82<;H#$1B1$1E!6#6?.>;1&*%G7%GH./2BA,>)0$E:;-2&43>C3%;$,;8:F2!>7*4H&''(&CH%>'/G9&.FF6F,G@A33/';/-<5'"?2G3)##0#+'??<8A'4:3.-$(GH&$;,D<C;A9A5;)?%H)0:.2.".0F1;*6"H2205A;;GD6%A%7@)!=25)&1;HC9,:
@r9993
TNNGTTANAGTNAGTAACTTAAAAGAGAGATCCTGTGTTGCNGCCAAATAAATTGCGGTTATTTT
+
%"!)&!%%)%!#+&%&#)"*$'*#(+!(*#)(#!((&%)!!)"!)*!()&+&*))&#+(++%*$&
@r9994
TTATCCCTTTGACGAATACGAGTTTGGAAAGCCAGTTGATCATCAGCAGGTAATCTGGAACCGCGAACGAATCAGCAACTCACAAAACGGGATGGTGAAAGAAATCAAAGGCGCGGACACGTTCA
+
)58)7ED#G.G)CF/!@29/>)@9<C?8E?>#@1%@<.DE1C<7B(B5#:>.A=;BE.DC2D$?)%7:A/07'C@:D.>!-G-:EG476!E#/5%A+,?&+)=?7F'2+:6796>B2'B@F0$&0
@r9995
ATCCGTTNCCGCCGGACTGCCAAACGTCAGCGAGCTGGTTGATATGGTTTACGAGTATTGCCGGCGAGGCCTGTATCCGGAAGCGGAGTCTTATCCGTGGAAATCAAACGCNCACTACTGGCTGGTTACCAACCTGTATCAGAACATGCGGGCCAATGC
+
#'$))(%"(*&$+&***!$$!+)"%%#&"#%'!%!&$$))+)*#"'*%&&$#&("+(&#+!+%++#+)!'"(&"&'($)((#*&*+#&$#$$&'!'+$%&!$#(((!%+&(+'($$(%!+%#!))%!"($%!'"*"&$$'#!%+!)&+)#(%(#%"$')
@r9996
ACTNAAGGATGCCAGCAAGCGCAGCATATCGCGCTGTGACCATGCTAGGGATCCCAAACCTTNCCCGACCCACCTGTTCACGCACTGTTAAGCCGCNGTATGACGCTCTGGTGGTGCAATGCCACAAAGAAGAGTCAATCGCAGA
+
'!)()+#+"%")%##)"$)'(%*+)(&'$#'+""!''*())!"&(*++%)+($'('%&&'%"(%$!$!$!(#'%#&$$*"+'&%!!&"''*+(%%$"!"+!(''&"($&#**!!(#$+#+"#+++&!!#$+%**+#$$+&!$"%#
@r9997
GCCGCTGTGCTTTCANTGGATTTCGGATAACAGAAAGGNCGGGAAATACCCAGNCTCGCTTTGTAACGGAGTAGACGAAAGTGATTGCGNCTACCCGGA
+
@!6;5'9,@FA=H-G<72)50G@2B@>7#$/%?H-F;497++D='.G?/(4@#"F#@<(+E=4#F&;&96A,?H/0E?1,6986%1D1$27D(@@*6#9
@r9998
CATTAAAGGGGCATCCGTCTACGGAAAGCCGGTGGCCAGCATGCCA
+
BD1FC>5*F>%84@$5G#(=H--3'4=4+%-A5DE1?@/E;2)"&7
@r9999
AATCTGCTCCNCCGACACGTTATGGAACTGGCGAGCCATCGCCGTCAGCCCCGACGTCGGGTCCGTGGTCAGCTTCCCGAAGGCTTCAGCGACCTTGTCCACC
+
D+%4F$/G$<1BA#$7"FA(C2$;B+79,@F%+<88B%0?&3<+BC83&-:+,4C?HF=E;97/'>/.)&4E,*,G3=7@4=5BE75+72D-*!C&*'%)<%0
@r10000
AACTGTTTCGGGATTGCATTTTGCAGACCTCTCTGCCTGCGATGGTTGGAGTTCCAGACGATACGTCGAAGTGACCAACTGCGGAATCGGTAGTAAGCGCCGCCTCTTTTCATCTCACTACCACA
+
893H?F//$,B%'@B/(4'9!&.8#2G082.$EHE@:*2@((B;62#C$/-1B#+:;C%=<>G31D47587EB,.("5&)%>;=>"-.?0:9+7)?G01:G'!&#3C=.1'%(;1#(02?*%'((